PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
25491532-6	2015	A substantial increase in FAAH activity was discovered toward NAEs in vitro in the presence of some of these synthetic alkamides, such as N-ethyllauroylamide (4).	alkamides	119-128	fatty acid amide hydrolase	Arabidopsis thaliana	26-30
12058332-2	2002	30 minutes after apical loading of 25 microg/ml 1/ 2, about 15 % of these alkamides were detectable on the basolateral side.	alkamides	74-83	interleukin 17F	Homo sapiens	45-52
29063362-0	2018	Piperine-like alkamides from Piper nigrum induce BDNF promoter and promote neurite outgrowth in Neuro-2a cells.	alkamides	14-23	brain derived neurotrophic factor	Mus musculus	49-53
25491532-8	2015	For several of these alkamides, an inhibition of seedling growth was observed with greater results in FAAH knockouts and less in FAAH over-expressing plants, suggesting that these alkamides could be hydrolyzed by FAAH in planta.	alkamides	21-30	fatty acid amide hydrolase	Arabidopsis thaliana	102-106
25491532-8	2015	For several of these alkamides, an inhibition of seedling growth was observed with greater results in FAAH knockouts and less in FAAH over-expressing plants, suggesting that these alkamides could be hydrolyzed by FAAH in planta.	alkamides	21-30	fatty acid amide hydrolase	Arabidopsis thaliana	129-133
25491532-8	2015	For several of these alkamides, an inhibition of seedling growth was observed with greater results in FAAH knockouts and less in FAAH over-expressing plants, suggesting that these alkamides could be hydrolyzed by FAAH in planta.	alkamides	21-30	fatty acid amide hydrolase	Arabidopsis thaliana	129-133
21985290-1	2011	This study aimed to shed light on the anti-inflammatory and hepatoprotective effect of the major alkamides dodeca-2E,4E,8Z,10Z(E)-tetraenoic acid isobutylamides (Alk-8/9), isolated from Echinacea purpurea roots, against acute fulminant hepatitis induced by lipopolysaccharide/D-galactosamine (LPS/D-GalN) in mice.	alkamides	97-106	activin A receptor, type 1	Mus musculus	162-167
21985290-1	2011	This study aimed to shed light on the anti-inflammatory and hepatoprotective effect of the major alkamides dodeca-2E,4E,8Z,10Z(E)-tetraenoic acid isobutylamides (Alk-8/9), isolated from Echinacea purpurea roots, against acute fulminant hepatitis induced by lipopolysaccharide/D-galactosamine (LPS/D-GalN) in mice.	alkamides	97-106	galanin and GMAP prepropeptide	Mus musculus	299-303
17599805-0	2007	Alkamides from Echinacea inhibit cyclooxygenase-2 activity in human neuroglioma cells.	alkamides	0-9	prostaglandin-endoperoxide synthase 2	Homo sapiens	33-49
21092239-2	2010	One likely mode of action is that alkamides from Echinacea bind to cannabinoid type 2 (CB2) receptors and induce a transient increase in intracellular Ca2+.	alkamides	34-43	cannabinoid receptor 2	Homo sapiens	87-90
19111603-13	2009	The polar fraction containing caffeic acid derivatives enhanced arginase activity, while the lipophilic fraction containing alkamides exhibited a potential of inhibiting NO production and iNOS expression.	alkamides	124-133	nitric oxide synthase 2, inducible	Mus musculus	188-192
17965178-7	2007	The involvement of cytokinins in mediating the observed activity of alkamides was tested using Arabidopsis mutants lacking one, two, or three of the putative cytokinin receptors CRE1, AHK2, and AHK3.	alkamides	68-77	CHASE domain containing histidine kinase protein	Arabidopsis thaliana	178-182
17965178-7	2007	The involvement of cytokinins in mediating the observed activity of alkamides was tested using Arabidopsis mutants lacking one, two, or three of the putative cytokinin receptors CRE1, AHK2, and AHK3.	alkamides	68-77	histidine kinase 2	Arabidopsis thaliana	184-188
17965178-7	2007	The involvement of cytokinins in mediating the observed activity of alkamides was tested using Arabidopsis mutants lacking one, two, or three of the putative cytokinin receptors CRE1, AHK2, and AHK3.	alkamides	68-77	histidine kinase 3	Arabidopsis thaliana	194-198
17599805-7	2007	Using an established short-term COX-2 activity assay, all three alkamides were shown to interfere with COX-2 activity.	alkamides	64-73	prostaglandin-endoperoxide synthase 2	Homo sapiens	32-37
17599805-7	2007	Using an established short-term COX-2 activity assay, all three alkamides were shown to interfere with COX-2 activity.	alkamides	64-73	prostaglandin-endoperoxide synthase 2	Homo sapiens	103-108
17599805-9	2007	Instead, increased COX-2 mRNA and protein levels were registered in the presence of the CO2 extract and most of the analyzed alkamides which caused, however, no stimulation of PG formation.	alkamides	125-134	prostaglandin-endoperoxide synthase 2	Homo sapiens	19-24
16547349-2	2006	Alkylamides (alkamides) from Echinacea modulate tumor necrosis factor alpha mRNA expression in human monocytes/macrophages via the cannabinoid type 2 (CB2) receptor (Gertsch, J., Schoop, R., Kuenzle, U., and Suter, A.	alkamides	13-22	cannabinoid receptor 2	Homo sapiens	151-154
16808005-0	2006	Mechanism-based inhibition of human liver microsomal cytochrome P450 2D6 (CYP2D6) by alkamides of Piper nigrum.	alkamides	85-94	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	53-72
16808005-0	2006	Mechanism-based inhibition of human liver microsomal cytochrome P450 2D6 (CYP2D6) by alkamides of Piper nigrum.	alkamides	85-94	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	74-80