PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 6638670-3 1983 Boluses of VIP injected intravenously (0.1 to 10 micrograms X kg-1) reversed in a dose-dependent manner the increase in lung resistance (RL) and the decrease in dynamic lung compliance (Cdyn) induced by an intravenously administered infusion of 5-hydroxytryptamine (5HT) (5 to 30 micrograms X kg-1 X min-1). cdyn 186-190 vasoactive intestinal peptide Felis catus 11-14 3616142-6 1987 Both an increase and a decrease of this level of Ptp induced an increase of RL and a decrease of Cdyn. cdyn 97-101 lithostathine Bos taurus 49-52 28558784-16 2017 significantly suppressed all RL values of MCh at 0.78 ~ 25 mg/mL and enhanced Cdyn values of MCh at 3.125 ~ 25 mg/mL compared to OVA-sensitized and -challenged control mice. cdyn 78-82 modifier of chinchilla Mus musculus 93-96 27060978-8 2016 The combined effects of RLX + TFF2 + DEX significantly reversed peribronchial inflammation score, airway epithelial damage, subepithelial extracellular matrix accumulation/fibronectin deposition and total lung collagen concentration (by 50-90%) and also normalized the reduction of cDyn. cdyn 282-286 relaxin 1 Mus musculus 24-27 28482384-5 2017 Result: Compared with CVVH, HVHF had the capacity to improve significantly the index of Cdyn(HVHF (2.3+-0.5) vs. CVVH (1.5+-0.5) ml/(cmH(2)O kg), 1 cmH(2)O=0.098 kPa, P<0.05)and Rrs(HVHF (22.0+-1.9) vs.CVVH (29.5+-1.5) cmH(2)O/(L s), P<0.05)at the time of 6 h, and decreased lung water accumulation(index of EVLWI in HVHF (22.7+-2.1) vs.CVVH (39.5+-2.6) ml/m(2,) P<0.01) at the time of 6 h, and the plasma concentration of cytokines(IL-6, IL-10, TNF-alpha)in the HVHF group had an obvious decline compared with those in the CVVH group at the time of 6 h( (200+-55) vs. (280+-61), (74+-17) vs. (102+-21), (54+-13) vs. (73+-21) pg/ml, all P<0.05). cdyn 88-92 interleukin 6 Homo sapiens 442-446 28482384-5 2017 Result: Compared with CVVH, HVHF had the capacity to improve significantly the index of Cdyn(HVHF (2.3+-0.5) vs. CVVH (1.5+-0.5) ml/(cmH(2)O kg), 1 cmH(2)O=0.098 kPa, P<0.05)and Rrs(HVHF (22.0+-1.9) vs.CVVH (29.5+-1.5) cmH(2)O/(L s), P<0.05)at the time of 6 h, and decreased lung water accumulation(index of EVLWI in HVHF (22.7+-2.1) vs.CVVH (39.5+-2.6) ml/m(2,) P<0.01) at the time of 6 h, and the plasma concentration of cytokines(IL-6, IL-10, TNF-alpha)in the HVHF group had an obvious decline compared with those in the CVVH group at the time of 6 h( (200+-55) vs. (280+-61), (74+-17) vs. (102+-21), (54+-13) vs. (73+-21) pg/ml, all P<0.05). cdyn 88-92 interleukin 10 Homo sapiens 448-453 28482384-5 2017 Result: Compared with CVVH, HVHF had the capacity to improve significantly the index of Cdyn(HVHF (2.3+-0.5) vs. CVVH (1.5+-0.5) ml/(cmH(2)O kg), 1 cmH(2)O=0.098 kPa, P<0.05)and Rrs(HVHF (22.0+-1.9) vs.CVVH (29.5+-1.5) cmH(2)O/(L s), P<0.05)at the time of 6 h, and decreased lung water accumulation(index of EVLWI in HVHF (22.7+-2.1) vs.CVVH (39.5+-2.6) ml/m(2,) P<0.01) at the time of 6 h, and the plasma concentration of cytokines(IL-6, IL-10, TNF-alpha)in the HVHF group had an obvious decline compared with those in the CVVH group at the time of 6 h( (200+-55) vs. (280+-61), (74+-17) vs. (102+-21), (54+-13) vs. (73+-21) pg/ml, all P<0.05). cdyn 88-92 tumor necrosis factor Homo sapiens 455-464 27060978-8 2016 The combined effects of RLX + TFF2 + DEX significantly reversed peribronchial inflammation score, airway epithelial damage, subepithelial extracellular matrix accumulation/fibronectin deposition and total lung collagen concentration (by 50-90%) and also normalized the reduction of cDyn. cdyn 282-286 trefoil factor 2 (spasmolytic protein 1) Mus musculus 30-34 1833368-2 1991 Intravenous injections of ET-1 (0.1-1 nmol/kg) increased transpulmonary pressure (Ptp) and lung resistance (RL) and decreased dynamic compliance (Cdyn) in a dose-related manner. cdyn 146-150 endothelin 1 Felis catus 26-30 8835645-2 1996 Electrical stimulation of the vagus nerve in atropine-treated and propranolol-treated guinea pigs caused a 38.1% decrease in dynamic compliance (Cdyn), which was suppressed by the combination of the tachykinin NK1-receptor antagonist (+/-)-CP-96345 and NK2-receptor antagonist SR 48968. cdyn 145-149 substance-K receptor Cavia porcellus 253-265 1378745-4 1992 The predominant effect of NKA was on Cdyn with little or no effect on RL. cdyn 37-41 tachykinin precursor 1 Homo sapiens 26-29 12617779-13 2003 CONCLUSION: R,R-FMT protected lung against increase of RL and reduction of Cdyn induced by bronchial challenge of ovalbumin in the asthma model of guinea pigs, and inhibited airway inflammation in the sensitized mice. cdyn 75-79 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 114-123 9541491-3 1998 A single exposure of the EC sensitized mice to aerosolized OVA induced eosinophilia in the bronchoalveolar lavage fluid and airway hyperresponsiveness to intravenous methacholine as assessed by measurement of pulmonary dynamic compliance (Cdyn). cdyn 239-243 ovalbumin (SERPINB14) Gallus gallus 59-62 1833368-7 1991 The ET-1 precursor ET-1-(1-38) (big ET-1) caused a significant slowly developing increase in Ptp, RL, and aortic pressure (PAO) and a decrease in Cdyn, whereas a monocyclic ET-1 analogue and ET-1-(16-21) hexapeptide fragment had little or no activity in the airways. cdyn 146-150 endothelin 1 Felis catus 4-8 1833368-7 1991 The ET-1 precursor ET-1-(1-38) (big ET-1) caused a significant slowly developing increase in Ptp, RL, and aortic pressure (PAO) and a decrease in Cdyn, whereas a monocyclic ET-1 analogue and ET-1-(16-21) hexapeptide fragment had little or no activity in the airways. cdyn 146-150 endothelin 1 Felis catus 19-23 1833368-7 1991 The ET-1 precursor ET-1-(1-38) (big ET-1) caused a significant slowly developing increase in Ptp, RL, and aortic pressure (PAO) and a decrease in Cdyn, whereas a monocyclic ET-1 analogue and ET-1-(16-21) hexapeptide fragment had little or no activity in the airways. cdyn 146-150 endothelin 1 Felis catus 19-23 1833368-7 1991 The ET-1 precursor ET-1-(1-38) (big ET-1) caused a significant slowly developing increase in Ptp, RL, and aortic pressure (PAO) and a decrease in Cdyn, whereas a monocyclic ET-1 analogue and ET-1-(16-21) hexapeptide fragment had little or no activity in the airways. cdyn 146-150 endothelin 1 Felis catus 19-23 1833368-7 1991 The ET-1 precursor ET-1-(1-38) (big ET-1) caused a significant slowly developing increase in Ptp, RL, and aortic pressure (PAO) and a decrease in Cdyn, whereas a monocyclic ET-1 analogue and ET-1-(16-21) hexapeptide fragment had little or no activity in the airways. cdyn 146-150 endothelin 1 Felis catus 19-23