PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
25130261-7	2014	For EHMC, a Michael-type reaction occurred, which resulted in addition of Boc-lysine or the tetrapeptide to the conjugated double bond.	ethylhexyl methoxycinnamate	4-8	BOC cell adhesion associated, oncogene regulated	Homo sapiens	74-77
31301543-8	2019	When exposed to EHMC alone, E2 and Vtg contents, Esr, Pgr, Vtg1, Cyp19a1 and Hsd17b1 gene expression levels decreased significantly, and T content and Ar and Hsd17b3 expression increased significantly, indicated that EHMC can produce anti-estrogen and androgen effect.	ethylhexyl methoxycinnamate	16-20	vitellogenin	Danio rerio	35-38
31301543-5	2019	Results showed that both EHMC and 3,5DCl2HAcP can lead to the increase of malondialdehyde (MDA) and glutathione (GSH) contents, superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR) activities in visceral mass compared with the corresponding control group, thus produced oxidative stress effect in organism and 3,5DCl2HAcP even showed stronger oxidative stress than EHMC.	ethylhexyl methoxycinnamate	25-29	catalase	Danio rerio	156-164
31301543-5	2019	Results showed that both EHMC and 3,5DCl2HAcP can lead to the increase of malondialdehyde (MDA) and glutathione (GSH) contents, superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR) activities in visceral mass compared with the corresponding control group, thus produced oxidative stress effect in organism and 3,5DCl2HAcP even showed stronger oxidative stress than EHMC.	ethylhexyl methoxycinnamate	25-29	catalase	Danio rerio	166-169
31301543-8	2019	When exposed to EHMC alone, E2 and Vtg contents, Esr, Pgr, Vtg1, Cyp19a1 and Hsd17b1 gene expression levels decreased significantly, and T content and Ar and Hsd17b3 expression increased significantly, indicated that EHMC can produce anti-estrogen and androgen effect.	ethylhexyl methoxycinnamate	16-20	estrogen receptor 1	Danio rerio	49-52
31301543-8	2019	When exposed to EHMC alone, E2 and Vtg contents, Esr, Pgr, Vtg1, Cyp19a1 and Hsd17b1 gene expression levels decreased significantly, and T content and Ar and Hsd17b3 expression increased significantly, indicated that EHMC can produce anti-estrogen and androgen effect.	ethylhexyl methoxycinnamate	16-20	progesterone receptor	Danio rerio	54-57
31301543-5	2019	Results showed that both EHMC and 3,5DCl2HAcP can lead to the increase of malondialdehyde (MDA) and glutathione (GSH) contents, superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR) activities in visceral mass compared with the corresponding control group, thus produced oxidative stress effect in organism and 3,5DCl2HAcP even showed stronger oxidative stress than EHMC.	ethylhexyl methoxycinnamate	25-29	glutathione reductase	Danio rerio	175-196
31301543-5	2019	Results showed that both EHMC and 3,5DCl2HAcP can lead to the increase of malondialdehyde (MDA) and glutathione (GSH) contents, superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR) activities in visceral mass compared with the corresponding control group, thus produced oxidative stress effect in organism and 3,5DCl2HAcP even showed stronger oxidative stress than EHMC.	ethylhexyl methoxycinnamate	25-29	glutathione reductase	Danio rerio	198-200
31301543-8	2019	When exposed to EHMC alone, E2 and Vtg contents, Esr, Pgr, Vtg1, Cyp19a1 and Hsd17b1 gene expression levels decreased significantly, and T content and Ar and Hsd17b3 expression increased significantly, indicated that EHMC can produce anti-estrogen and androgen effect.	ethylhexyl methoxycinnamate	16-20	vitellogenin 1	Danio rerio	59-63
31301543-8	2019	When exposed to EHMC alone, E2 and Vtg contents, Esr, Pgr, Vtg1, Cyp19a1 and Hsd17b1 gene expression levels decreased significantly, and T content and Ar and Hsd17b3 expression increased significantly, indicated that EHMC can produce anti-estrogen and androgen effect.	ethylhexyl methoxycinnamate	16-20	cytochrome P450, family 19, subfamily A, polypeptide 1a	Danio rerio	65-72
31301543-8	2019	When exposed to EHMC alone, E2 and Vtg contents, Esr, Pgr, Vtg1, Cyp19a1 and Hsd17b1 gene expression levels decreased significantly, and T content and Ar and Hsd17b3 expression increased significantly, indicated that EHMC can produce anti-estrogen and androgen effect.	ethylhexyl methoxycinnamate	16-20	hydroxysteroid (17-beta) dehydrogenase 1	Danio rerio	77-84
31301543-8	2019	When exposed to EHMC alone, E2 and Vtg contents, Esr, Pgr, Vtg1, Cyp19a1 and Hsd17b1 gene expression levels decreased significantly, and T content and Ar and Hsd17b3 expression increased significantly, indicated that EHMC can produce anti-estrogen and androgen effect.	ethylhexyl methoxycinnamate	16-20	androgen receptor	Danio rerio	151-153
31301543-8	2019	When exposed to EHMC alone, E2 and Vtg contents, Esr, Pgr, Vtg1, Cyp19a1 and Hsd17b1 gene expression levels decreased significantly, and T content and Ar and Hsd17b3 expression increased significantly, indicated that EHMC can produce anti-estrogen and androgen effect.	ethylhexyl methoxycinnamate	16-20	hydroxysteroid (17-beta) dehydrogenase 3	Danio rerio	158-165