PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2469637-0	1989	DMC1: a monoclonal antibody produced from histiocytosis X cells which reacts with the native CD1a molecule of human epidermal Langerhans cells.	dmc1	0-4	CD1a molecule	Homo sapiens	93-106
28476890-8	2017	On the basis of these findings, we describe models for how sequence imperfections may affect base triplet recognition by Rad51/RecA family members, and we discuss how these models and our results may relate to the different biological roles of RecA, Rad51, and Dmc1.	dmc1	261-265	RAD51 recombinase	Homo sapiens	121-126
34009315-0	2021	RAD51 supports DMC1 by inhibiting the SMC5/6 complex during meiosis.	dmc1	15-19	structural maintenance of chromosomes 5	Arabidopsis thaliana	38-44
34009315-3	2021	Here we show that RAD51 functions as an interacting protein to restrain the Structural Maintenance of Chromosomes5/6 (SMC5/6) complex from inhibiting DMC1.	dmc1	150-154	structural maintenance of chromosomes 5	Arabidopsis thaliana	118-124
34009315-6	2021	This study not only identified the long-sought-after function of RAD51 in meiosis but also discovered the inhibition of SMC5/6 on DMC1 as a control mechanism during meiotic recombination.	dmc1	130-134	structural maintenance of chromosomes 5	Arabidopsis thaliana	120-126
30301803-0	2018	Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase.	dmc1	29-33	DNA helicase SRS2	Saccharomyces cerevisiae S288C	63-67
30301803-5	2018	Here, we show that the meiosis-specific recombinase Dmc1 is a potent inhibitor of Srs2.	dmc1	52-56	DNA helicase SRS2	Saccharomyces cerevisiae S288C	82-86
30301803-6	2018	Biochemical and single-molecule assays demonstrate that Dmc1 acts by inhibiting Srs2 ATP hydrolysis activity, which prevents the motor protein from undergoing ATP hydrolysis-dependent translocation on Dmc1-bound recombination intermediates.	dmc1	56-60	DNA helicase SRS2	Saccharomyces cerevisiae S288C	80-84
30301803-6	2018	Biochemical and single-molecule assays demonstrate that Dmc1 acts by inhibiting Srs2 ATP hydrolysis activity, which prevents the motor protein from undergoing ATP hydrolysis-dependent translocation on Dmc1-bound recombination intermediates.	dmc1	201-205	DNA helicase SRS2	Saccharomyces cerevisiae S288C	80-84
30301803-7	2018	We propose a model in which Dmc1 helps contribute to cross-over formation during meiosis by antagonizing the antirecombinase activity of Srs2.	dmc1	28-32	DNA helicase SRS2	Saccharomyces cerevisiae S288C	137-141
31371435-6	2019	Remarkably, RAD-51 from Caenorhabditis elegans, an organism without Dmc1, has acquired "Dmc1-like" amino acids.	dmc1	68-72	DNA repair protein RAD51 homolog	Caenorhabditis elegans	12-18
31371435-6	2019	Remarkably, RAD-51 from Caenorhabditis elegans, an organism without Dmc1, has acquired "Dmc1-like" amino acids.	dmc1	88-92	DNA repair protein RAD51 homolog	Caenorhabditis elegans	12-18
28476890-8	2017	On the basis of these findings, we describe models for how sequence imperfections may affect base triplet recognition by Rad51/RecA family members, and we discuss how these models and our results may relate to the different biological roles of RecA, Rad51, and Dmc1.	dmc1	261-265	RAD51 recombinase	Homo sapiens	127-131
28476890-8	2017	On the basis of these findings, we describe models for how sequence imperfections may affect base triplet recognition by Rad51/RecA family members, and we discuss how these models and our results may relate to the different biological roles of RecA, Rad51, and Dmc1.	dmc1	261-265	RAD51 recombinase	Homo sapiens	244-248
28249986-4	2017	Mek1 downregulates the mitotic recombinase Rad51, indirectly promoting interhomolog strand invasion by the meiosis-specific recombinase Dmc1.	dmc1	136-140	serine/threonine protein kinase MEK1	Saccharomyces cerevisiae S288C	0-4
28249986-4	2017	Mek1 downregulates the mitotic recombinase Rad51, indirectly promoting interhomolog strand invasion by the meiosis-specific recombinase Dmc1.	dmc1	136-140	recombinase RAD51	Saccharomyces cerevisiae S288C	43-48
20421598-7	2010	The pattern of DSB repair in haploids containing Dmc1 and/or Rad51 indicates that Mek1 acts on Rad51-specific recombination processes.	dmc1	49-53	serine/threonine protein kinase MEK1	Saccharomyces cerevisiae S288C	82-86
24465215-0	2014	Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks.	dmc1	84-88	recombinase RAD51	Saccharomyces cerevisiae S288C	19-24
24465215-4	2014	This paradox has recently been explained by the finding that Rad51 protein, but not its strand exchange activity, promotes Dmc1 function in budding yeast.	dmc1	123-127	recombinase RAD51	Saccharomyces cerevisiae S288C	61-66
24465215-10	2014	These results support the idea that down-regulation of Rad51 activity is important during meiosis to prevent Rad51 from competing with Dmc1 for repair of meiotic DSBs.	dmc1	135-139	recombinase RAD51	Saccharomyces cerevisiae S288C	55-60
24465215-10	2014	These results support the idea that down-regulation of Rad51 activity is important during meiosis to prevent Rad51 from competing with Dmc1 for repair of meiotic DSBs.	dmc1	135-139	recombinase RAD51	Saccharomyces cerevisiae S288C	109-114
23759310-9	2013	Moreover, Hormad1 deficiency rescued Dmc1(-/-) oocytes.	dmc1	37-41	HORMA domain containing 1	Mus musculus	10-17
22745819-3	2012	The reduction of DSB formation caused by the pch2 mutation is most prominent in the sae2 mutant background, whereas the impact remains mild in the rad51 dmc1 double mutant background.	dmc1	153-157	Pch2p	Saccharomyces cerevisiae S288C	45-49
22549958-6	2012	Consistent with the hypothesis that ATR activity on chromatin plays important roles in the quality control of meiotic prophase, HORMAD2 is required for the elimination of the asynaptic Spo11(-/-), but not the asynaptic and DSB repair-defective Dmc1(-/-) oocytes.	dmc1	244-248	HORMA domain containing 2	Mus musculus	128-135
15928951-6	2005	Therefore, Mei1 can be positioned upstream of Dmc1 in the genetic pathway that operates during mammalian meiosis.	dmc1	46-50	meiotic double-stranded break formation protein 1	Homo sapiens	11-15
18329363-6	2008	Thus, Hop1 is a meiosis-specific adaptor protein of the Mec1/Tel1 signaling pathway that ensures interhomolog recombination by preventing Dmc1-independent repair of meiotic DSBs.	dmc1	138-142	ATR serine/threonine kinase	Homo sapiens	56-60
18329363-6	2008	Thus, Hop1 is a meiosis-specific adaptor protein of the Mec1/Tel1 signaling pathway that ensures interhomolog recombination by preventing Dmc1-independent repair of meiotic DSBs.	dmc1	138-142	ETS variant transcription factor 6	Homo sapiens	61-65
16818601-0	2006	Red-Hed regulation: recombinase Rad51, though capable of playing the leading role, may be relegated to supporting Dmc1 in budding yeast meiosis.	dmc1	114-118	recombinase RAD51	Saccharomyces cerevisiae S288C	32-37
15917244-1	2005	Rad51 and its meiotic homolog Dmc1 are key proteins of homologous recombination in eukaryotes.	dmc1	30-34	RAD51 recombinase	Homo sapiens	0-5
15928951-0	2005	Mei1 is epistatic to Dmc1 during mouse meiosis.	dmc1	21-25	meiotic double-stranded break formation protein 1	Mus musculus	0-4
14667413-7	2003	We conclude that Rad51 is capable of carrying out a homology search independently, whereas Dmc1 requires additional factors such as Hop2.	dmc1	91-95	Hop2p	Saccharomyces cerevisiae S288C	132-136
12526806-5	2002	Red1 promotes DSB formation in both R- and G-bands and then promotes Dmc1 loading, specifically counteracting disfavoring R-band effects.	dmc1	69-73	adenosine deaminase RNA specific B1	Homo sapiens	0-4
10511544-7	1999	The genes RED1, MEK1, RAD24, RAD17, and MEC1 are required for meiotic prophase arrest induced by a dmc1 mutation, which defines a meiotic recombination checkpoint.	dmc1	99-103	Red1p	Saccharomyces cerevisiae S288C	10-14
10511544-7	1999	The genes RED1, MEK1, RAD24, RAD17, and MEC1 are required for meiotic prophase arrest induced by a dmc1 mutation, which defines a meiotic recombination checkpoint.	dmc1	99-103	serine/threonine protein kinase MEK1	Saccharomyces cerevisiae S288C	16-20
10511544-7	1999	The genes RED1, MEK1, RAD24, RAD17, and MEC1 are required for meiotic prophase arrest induced by a dmc1 mutation, which defines a meiotic recombination checkpoint.	dmc1	99-103	Rad24p	Saccharomyces cerevisiae S288C	22-27
10511544-7	1999	The genes RED1, MEK1, RAD24, RAD17, and MEC1 are required for meiotic prophase arrest induced by a dmc1 mutation, which defines a meiotic recombination checkpoint.	dmc1	99-103	Rad17p	Saccharomyces cerevisiae S288C	29-34
10511544-7	1999	The genes RED1, MEK1, RAD24, RAD17, and MEC1 are required for meiotic prophase arrest induced by a dmc1 mutation, which defines a meiotic recombination checkpoint.	dmc1	99-103	protein kinase MEC1	Saccharomyces cerevisiae S288C	40-44
10511544-10	1999	The mutants in class II, including a dmc1 mutant, confer a dominant meiotic lethal phenotype in diploid SPO13 meiosis in our strain background, and they identify alleles of UBR1, INP52, BUD3, PET122, ELA1, and MSC1-MSC3.	dmc1	37-41	Pet122p	Saccharomyces cerevisiae S288C	192-198
10511544-10	1999	The mutants in class II, including a dmc1 mutant, confer a dominant meiotic lethal phenotype in diploid SPO13 meiosis in our strain background, and they identify alleles of UBR1, INP52, BUD3, PET122, ELA1, and MSC1-MSC3.	dmc1	37-41	elongin A	Saccharomyces cerevisiae S288C	200-204
10511544-10	1999	The mutants in class II, including a dmc1 mutant, confer a dominant meiotic lethal phenotype in diploid SPO13 meiosis in our strain background, and they identify alleles of UBR1, INP52, BUD3, PET122, ELA1, and MSC1-MSC3.	dmc1	37-41	Msc1p	Saccharomyces cerevisiae S288C	210-214
10511544-10	1999	The mutants in class II, including a dmc1 mutant, confer a dominant meiotic lethal phenotype in diploid SPO13 meiosis in our strain background, and they identify alleles of UBR1, INP52, BUD3, PET122, ELA1, and MSC1-MSC3.	dmc1	37-41	Msc3p	Saccharomyces cerevisiae S288C	215-219
11994286-9	2002	Finally, we show that removal of all 4 positively charged amino acids in the 20-44 azurocidin sequence (DMC1: R23Q,H24S,H32S,R34Q), a region previously thought to contain an antimicrobial domain, does not affect the activity of the protein against E. coli, Streptococcus faecalis, and C. albicans.	dmc1	104-108	azurocidin 1	Bos taurus	83-93
9679065-3	1998	Rad52 and RPA foci are distinct from those formed by Rad51, and its meiosis-specific relative Dmc1, in that they are also detected in meiosis during replication.	dmc1	94-98	recombinase RAD52	Saccharomyces cerevisiae S288C	0-5
9021132-7	1997	The other group of seven genes, designated the dmc1 group, is orthologous to the Saccharomyces DMC1 gene.	dmc1	47-51	recombinase DMC1	Saccharomyces cerevisiae S288C	95-99