PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 33110441-11 2020 The putative targets of YZG that treat ODUB mainly involved PTGS1, PTGS2, ALOX5, CASP3, LTA4H, F7 and F10. yzg 24-27 prostaglandin-endoperoxide synthase 1 Homo sapiens 60-65 33110441-11 2020 The putative targets of YZG that treat ODUB mainly involved PTGS1, PTGS2, ALOX5, CASP3, LTA4H, F7 and F10. yzg 24-27 prostaglandin-endoperoxide synthase 2 Homo sapiens 67-72 33110441-11 2020 The putative targets of YZG that treat ODUB mainly involved PTGS1, PTGS2, ALOX5, CASP3, LTA4H, F7 and F10. yzg 24-27 arachidonate 5-lipoxygenase Homo sapiens 74-79 33110441-11 2020 The putative targets of YZG that treat ODUB mainly involved PTGS1, PTGS2, ALOX5, CASP3, LTA4H, F7 and F10. yzg 24-27 caspase 3 Homo sapiens 81-86 33110441-11 2020 The putative targets of YZG that treat ODUB mainly involved PTGS1, PTGS2, ALOX5, CASP3, LTA4H, F7 and F10. yzg 24-27 leukotriene A4 hydrolase Homo sapiens 88-93 28848441-9 2017 Flavin-containing monooxygenase 1 (FMO1) and FMO3 participated in the conversion of YZG-331 in rat LMs. yzg 84-87 flavin containing dimethylaniline monoxygenase 1 Rattus norvegicus 0-33 28848441-9 2017 Flavin-containing monooxygenase 1 (FMO1) and FMO3 participated in the conversion of YZG-331 in rat LMs. yzg 84-87 flavin containing dimethylaniline monoxygenase 1 Rattus norvegicus 35-39 28848441-9 2017 Flavin-containing monooxygenase 1 (FMO1) and FMO3 participated in the conversion of YZG-331 in rat LMs. yzg 84-87 flavin containing dimethylaniline monoxygenase 3 Rattus norvegicus 45-49 27612629-3 2016 The activity of P-gp ATPase was both induced by YZG-331 and verapamil, a typical P-gp inhibitor, but affinity of YZG-331 for P-gp was lower than that of verapamil. yzg 48-51 PGP Canis lupus familiaris 16-20 27612629-3 2016 The activity of P-gp ATPase was both induced by YZG-331 and verapamil, a typical P-gp inhibitor, but affinity of YZG-331 for P-gp was lower than that of verapamil. yzg 48-51 PGP Canis lupus familiaris 81-85 27612629-3 2016 The activity of P-gp ATPase was both induced by YZG-331 and verapamil, a typical P-gp inhibitor, but affinity of YZG-331 for P-gp was lower than that of verapamil. yzg 48-51 PGP Canis lupus familiaris 81-85 27612629-4 2016 The docking analyses further elucidated the binding relationship of YZG-331 and P-gp. yzg 68-71 PGP Canis lupus familiaris 80-84 27612629-5 2016 The directional transport of YZG-331 was disappeared in Caco-2 and MDCK-MDR1 cells when the P-gp activity was blocked. yzg 29-32 PGP Canis lupus familiaris 92-96 27612629-11 2016 The intestine and brain permeability of YZG-331 can be restricted, at least in part, by P-gp. yzg 40-43 PGP Canis lupus familiaris 88-92 17058837-2 2006 METHODS: Intracellular cytokines secreted by Th1/Th2 were measured using flow cytometry in 24 healthy subjects and 31 IgAN patients treated by YZG before and after treatment. yzg 143-146 negative elongation factor complex member C/D Homo sapiens 45-48 17058837-4 2006 After YZG treatment, the level of IFN-gamma increased and IL-10 level decreased (P < 0.01). yzg 6-9 interferon gamma Homo sapiens 34-43 17058837-4 2006 After YZG treatment, the level of IFN-gamma increased and IL-10 level decreased (P < 0.01). yzg 6-9 interleukin 10 Homo sapiens 58-63