PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
9361193-3	1997	Treatment of these two cell types with BMP-2 for 4 weeks in the presence of beta-glycerophosphate and ascorbic acid results in mineralization of their matrix.	beta-glycerophosphoric acid	76-97	bone morphogenetic protein 2	Homo sapiens	39-44
9322963-5	1997	Levels of alkaline phosphatase activity in BMSC expanded with FGF-2 were significantly lower (56%) than control and, after stimulation with ascorbic acid, betaGlycerophosphate and dexamethasone, FGF-2 expanded BMSC deposited approximately 3-fold more mineralized matrix than control cells.	beta-glycerophosphoric acid	155-175	fibroblast growth factor 2	Homo sapiens	195-200
8079661-4	1994	In this report, we describe the effects of TGF-beta 1 on first subcultures of fetal rat osteoblasts obtained from calvarial bones and cultured from confluence with ascorbic acid and beta-glycerophosphate.	beta-glycerophosphoric acid	182-203	transforming growth factor, beta 1	Rattus norvegicus	43-53
7768987-3	1995	NF1 showed a relatively higher specific ALP activity, which has further increased in response to dexamethasone + beta-glycerophosphate (beta GP) (Dex medium) coordinately with a decrease in cell proliferation.	beta-glycerophosphoric acid	113-134	neurofibromin 1	Rattus norvegicus	0-3
7768987-3	1995	NF1 showed a relatively higher specific ALP activity, which has further increased in response to dexamethasone + beta-glycerophosphate (beta GP) (Dex medium) coordinately with a decrease in cell proliferation.	beta-glycerophosphoric acid	113-134	orosomucoid 1	Rattus norvegicus	136-143
8608800-3	1996	mRNA for the osteoblast-specific protein osteocalcin was well as granulocyte colony-stimulating factor (G-CSF), transforming growth factor-beta 1 (TGF-beta 1), and tumor necrosis factor-alpha (TNF-alpha) was produced by the MG-63 and SaOS-2 cells, like primary human cells, in the presence and absence of L-ascorbate and beta-glycerol phosphate.	beta-glycerophosphoric acid	321-344	bone gamma-carboxyglutamate protein	Homo sapiens	41-52
8080278-3	1994	The kinetic studies on the ALP activity with varying the p-nitrophenyl phosphate or beta-glycerophosphate concentrations showed that the inhibition of the enzyme activity by treatment with these oxidizing agents is mainly due to a decrease in the Vmax value rather than a change in the Km value.	beta-glycerophosphoric acid	84-105	alkaline phosphatase, placental	Homo sapiens	27-30
8400287-1	1993	Murine bone marrow cells synthesize bone proteins, including alkaline phosphatase (ALP), collagen type I, and osteocalcin, and form a mineralized extracellular matrix when cultured in the presence of beta-glycerophosphate and vitamin C.	beta-glycerophosphoric acid	200-221	bone gamma-carboxyglutamate protein 2	Mus musculus	110-121
8126008-5	1994	It was inhibited by [ethylenebis(oxyethylenenitrilo)]tetraacetic acid and beta-glycerophosphate at concentrations routinely used to stabilize p70S6K and p90rsk.	beta-glycerophosphoric acid	74-95	ribosomal protein S6 kinase B1	Rattus norvegicus	142-148
8260697-1	1993	In the presence of beta-glycerophosphate and vitamin C, cultures of normal mouse bone marrow cells form three-dimensional structures that stain positive with the Von Kossa technique and express alkaline phosphatase (ALP), collagen type I, and osteocalcin.	beta-glycerophosphoric acid	19-40	bone gamma-carboxyglutamate protein 2	Mus musculus	243-254
1341708-9	1992	Cathepsin B activation by BK or L-Arg but not des-Arg9-BK was inhibited by L-NMMA (inhibitor of NO synthesis), and the activation by L-Arg was enhanced by beta-glycerophosphate (beta-GP: inhibitor of phosphatases), while the activation by BK or des-Arg9-BK was inhibited by beta-GP.	beta-glycerophosphoric acid	155-176	cathepsin B	Rattus norvegicus	0-11
1381978-8	1992	While the level of c-src protein decreased approximately 2.5-fold in hypertrophic chondrocytes after 17 days of beta-glycerophosphate treatment, the specific activity of pp60c-src kinase increased approximately 3-fold in the cells that could be induced to mineralize but remained unchanged in cells that did not exhibit this property.	beta-glycerophosphoric acid	112-133	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	19-24
1328198-7	1992	In long-term (11-17 day) cultures of osteoblasts in the presence of beta-glycerophosphate and L(+)-ascorbate, hOP-1 markedly increased the rate of mineralization as measured by the number of mineral nodules per well (20-fold increase at 20 ng of hOP-1/ml).	beta-glycerophosphoric acid	68-89	bone morphogenetic protein 7	Homo sapiens	110-115
1311309-5	1992	rsk kinase is inhibited by low concentrations of heparin as well as by beta-glycerophosphate and calcium.	beta-glycerophosphoric acid	71-92	ribosomal protein S6 kinase A3 L homeolog	Xenopus laevis	0-3
1642142-4	1992	In the presence of ascorbic acid and beta-glycerol phosphate, insulin has a dose-dependent effect on the morphology of the mineralized bone matrix produced.	beta-glycerophosphoric acid	37-60	insulin	Bos taurus	62-69
1328261-6	1992	The p34cdc2-cyclin complex can be solubilised by 80 mM beta-glycerophosphate (in the standard MPF extraction buffer) or by high salt concentrations.	beta-glycerophosphoric acid	55-76	cyclin-dependent kinase 1 L homeolog	Xenopus laevis	4-11
1328261-6	1992	The p34cdc2-cyclin complex can be solubilised by 80 mM beta-glycerophosphate (in the standard MPF extraction buffer) or by high salt concentrations.	beta-glycerophosphoric acid	55-76	proliferating cell nuclear antigen S homeolog	Xenopus laevis	12-18
2016285-12	1991	The stimulated MBP-phosphorylating activity of p44mpk in cytosols from maturing oocytes was partly stabilized by the presence of the phosphatase inhibitor beta-glycerol phosphate.	beta-glycerophosphoric acid	155-178	myelin basic protein	Homo sapiens	15-18
2016285-12	1991	The stimulated MBP-phosphorylating activity of p44mpk in cytosols from maturing oocytes was partly stabilized by the presence of the phosphatase inhibitor beta-glycerol phosphate.	beta-glycerophosphoric acid	155-178	interferon induced protein 44	Homo sapiens	47-50
2494945-0	1989	The binding of beta-glycerophosphate to glycogen phosphorylase b in the crystal.	beta-glycerophosphoric acid	15-36	glycogen phosphorylase B	Homo sapiens	40-64
34906295-6	2021	Results 30 mmol/L of beta glycerophosphate had the best effect in inducing EndoMT, and the expression of PCSK9 mRNA and protein was up-regulated when EndoMT occurred.	beta-glycerophosphoric acid	21-42	proprotein convertase subtilisin/kexin type 9	Homo sapiens	105-110
34906295-6	2021	Results 30 mmol/L of beta glycerophosphate had the best effect in inducing EndoMT, and the expression of PCSK9 mRNA and protein was up-regulated when EndoMT occurred.	beta-glycerophosphoric acid	21-42	mannosidase endo-alpha	Homo sapiens	150-156
35354793-4	2022	During mouse vascular smooth muscle cell (VSMC) calcification induced by beta-glycerophosphate (beta-GP), the pyroptosis level was increased, as evidenced by the upregulated expression of pyroptosis-related proteins (cleaved CASP1, GSDMD-N, and IL1B) and pyroptotic cell death (increased numbers of PI-positive cells and LDH release).	beta-glycerophosphoric acid	73-94	caspase 1	Mus musculus	225-230
35426795-6	2022	Cultured mouse aortic smooth muscle cells were treated with 10 mmol/L beta-glycerophosphate for 14 days to induce calcification, and the changes in BI-1 and OPA1 protein expressions were examined using Western blotting and cell apoptosis was detected using TUNEL staining.	beta-glycerophosphoric acid	70-91	transmembrane BAX inhibitor motif containing 6	Mus musculus	148-152
35426795-6	2022	Cultured mouse aortic smooth muscle cells were treated with 10 mmol/L beta-glycerophosphate for 14 days to induce calcification, and the changes in BI-1 and OPA1 protein expressions were examined using Western blotting and cell apoptosis was detected using TUNEL staining.	beta-glycerophosphoric acid	70-91	OPA1, mitochondrial dynamin like GTPase	Mus musculus	157-161
2155777-9	1990	In "prophase extracts", spontaneous activation of the cdc2 kinase is inhibited by beta-glycerophosphate and NaF, but not by okadaic acid, inhibitor 1 and inhibitor 2 or divalent cation chelation.	beta-glycerophosphoric acid	82-103	cyclin-dependent kinase 1 S homeolog	Xenopus laevis	54-58
2292433-2	1990	Hydroxyl radicals abstract hydrogen atoms from glycerol-2-phosphate with a specific rate constant of (7.0 +/- 1.5) x 10(8) M-1s-1 forming the beta-phospho radical as the major product.	beta-glycerophosphoric acid	47-67	tumor associated calcium signal transducer 2	Homo sapiens	123-129
29331905-6	2018	In this system, IL-4, an anti-inflammatory cytokine, was loaded in TNT and IFN-gamma, a pro-inflammatory cytokine, was located between two hydrogel layers of chitosan/beta-glycerophosphate disodium and carboxymethyl chitosan/genipin.	beta-glycerophosphoric acid	167-197	interferon gamma	Homo sapiens	75-84
34906295-1	2021	Objective To investigate the protective effect of proprotein convertase subtilisin/kexin type 9 (PCSK9) knockdown on endothelial-to-mesenchymal transition (EndoMT) induced by beta glycerophosphate, dexamethasone, and L-ascorbic acid in human aortic endothelial cells (HAECs).	beta-glycerophosphoric acid	175-196	proprotein convertase subtilisin/kexin type 9	Homo sapiens	50-95
34906295-1	2021	Objective To investigate the protective effect of proprotein convertase subtilisin/kexin type 9 (PCSK9) knockdown on endothelial-to-mesenchymal transition (EndoMT) induced by beta glycerophosphate, dexamethasone, and L-ascorbic acid in human aortic endothelial cells (HAECs).	beta-glycerophosphoric acid	175-196	proprotein convertase subtilisin/kexin type 9	Homo sapiens	97-102
34906295-1	2021	Objective To investigate the protective effect of proprotein convertase subtilisin/kexin type 9 (PCSK9) knockdown on endothelial-to-mesenchymal transition (EndoMT) induced by beta glycerophosphate, dexamethasone, and L-ascorbic acid in human aortic endothelial cells (HAECs).	beta-glycerophosphoric acid	175-196	mannosidase endo-alpha	Homo sapiens	156-162
34906295-6	2021	Results 30 mmol/L of beta glycerophosphate had the best effect in inducing EndoMT, and the expression of PCSK9 mRNA and protein was up-regulated when EndoMT occurred.	beta-glycerophosphoric acid	21-42	mannosidase endo-alpha	Homo sapiens	75-81
34398360-7	2021	Combined with the results of Alizarin Red S staining, we discovered that beta-glycerophosphate (beta-Gp)-induced the osteoblastic differentiation of VSMCs was significantly reversed by gAd treatment.	beta-glycerophosphoric acid	73-94	orosomucoid 1	Rattus norvegicus	96-103
35272550-0	2022	MiR-140-5p upregulation suppressed beta-glycerophosphate-induced vascular smooth muscle cell calcification via targeting TLR4.	beta-glycerophosphoric acid	35-56	microRNA 140	Homo sapiens	0-7
35272550-0	2022	MiR-140-5p upregulation suppressed beta-glycerophosphate-induced vascular smooth muscle cell calcification via targeting TLR4.	beta-glycerophosphoric acid	35-56	toll like receptor 4	Homo sapiens	121-125
35272550-2	2022	METHODS: The calcium nodules formed in transfected and beta-glycerophosphate (beta-GP)-treated VSMCs were observed using Alizarin Red S staining, and alkaline phosphatase (ALP) activity was determined.	beta-glycerophosphoric acid	55-76	alkaline phosphatase, placental	Homo sapiens	150-170
35272550-2	2022	METHODS: The calcium nodules formed in transfected and beta-glycerophosphate (beta-GP)-treated VSMCs were observed using Alizarin Red S staining, and alkaline phosphatase (ALP) activity was determined.	beta-glycerophosphoric acid	55-76	alkaline phosphatase, placental	Homo sapiens	172-175
35255258-9	2022	RESULTS: Irisin alleviated VSMCs calcification induced by beta-glycerophosphate.	beta-glycerophosphoric acid	58-79	fibronectin type III domain containing 5	Homo sapiens	9-15
35184400-10	2022	In vitro experiments revealed that OMD mRNA was upregulated in SMCs stimulated with IFNgamma, BMP2, TGFbeta1, phosphate and beta-glycerophosphate, and by administration of recombinant human OMD protein (rhOMD).	beta-glycerophosphoric acid	124-145	osteomodulin	Homo sapiens	35-38
2494945-1	1989	The binding of beta-glycerophosphate (glycerol-2-P) to glycogen phosphorylase b in the crystal has been studied by X-ray diffraction at 3 A resolution.	beta-glycerophosphoric acid	15-36	glycogen phosphorylase B	Homo sapiens	55-79
2822412-1	1987	If confluent fibroblasts are infected with the swine alpha-herpes virus, pseudorabies virus, ribosomal protein S6 becomes phosphorylated after a lag of approximately 2 h. When cell-free extracts were prepared from such cells in the presence of glycerol 2-phosphate and EGTA, a ribosomal protein S6 kinase activity was found to appear at approximately the same time as the phosphorylation in vivo.	beta-glycerophosphoric acid	244-264	ribosomal protein S6	Homo sapiens	93-113
557464-15	1977	By inhibiting alkaline phosphomonoesterase with 0.1 mM of L-p-bromotetramisole or 16 mM of beta-glycerophosphate, 3beta-HSD was shown to be exclusively NAD-linked.	beta-glycerophosphoric acid	91-112	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	Rattus norvegicus	114-123
2415245-10	1986	Addition of the phosphatase inhibitor glycerol-2-phosphate partly prevented breakdown of the newly formed 5-fluorouridine 5"-monophosphate and enabled measurement of OPRT.	beta-glycerophosphoric acid	38-58	uridine monophosphate synthetase	Homo sapiens	166-170
20964-1	1977	The pH dependence of the human prostatic acid phosphatase-catalyzed hydrolysis of p-nitrophenyl phosphate and beta-glyceryl phosphate has been studied over a wide range of pH and the values of Km and V calculated with the aid of the Cleland HYPER program.	beta-glycerophosphoric acid	110-133	acid phosphatase 3	Homo sapiens	31-57
3030755-2	1987	In postribosomal extracts of these cells, prepared in the presence of glycerol 2-phosphate and EGTA, a ribosomal protein S6 kinase was detected.	beta-glycerophosphoric acid	70-90	40S ribosomal protein S6	Mesocricetus auratus	103-123
191438-1	1977	Peptidyldipeptide hydrolase [angiotensin I-converting enzyme, EC 3.4.15.1] was inhibited by inorganic and organic phosphorus compounds tested, except for beta-glycerophosphate, 5"-AMP, and 5"-ADP, at the reagent concentrations used.	beta-glycerophosphoric acid	154-175	angiotensin I converting enzyme	Homo sapiens	29-60
34016793-1	2021	In the present study, the effects and mechanism of action of U50,488H (a selective kappa-opioid receptor agonist) on calcification of rat vascular smooth muscle cells (VSMCs) induced by beta-glycerophosphate (beta-GP) were investigated.	beta-glycerophosphoric acid	186-207	orosomucoid 1	Rattus norvegicus	209-216
32703409-5	2020	Interestingly, five days after treatment of primary osteoblasts with ascorbic acid and beta glycerophosphate, protein levels of both DLL1 and NICD increased transiently, indicating that DLL1 activates NOTCH1 in primary cultured osteoblasts.	beta-glycerophosphoric acid	87-108	delta like canonical Notch ligand 1	Rattus norvegicus	186-190
33434566-9	2021	TGF-beta1 together with the mineralization medium (MM: consisting of ascorbic acid, dexamethasone and beta-glycerophosphate) increased the Alizarin Red-stained area on days 7 and 14.	beta-glycerophosphoric acid	102-123	transforming growth factor beta 1	Homo sapiens	0-9
32839065-1	2020	The main goal of this study was to explore the beneficial effect of nerve growth factor (NGF)-overexpressing of human adipose-derived mesenchymal stem cells (hADSCs) encapsulated in injectable chitosan/beta-glycerophosphate/hydroxyethylcellulose (CS/beta-GP/HEC) hydrogel for spinal cord regeneration.	beta-glycerophosphoric acid	202-223	nerve growth factor	Homo sapiens	68-87
32839065-1	2020	The main goal of this study was to explore the beneficial effect of nerve growth factor (NGF)-overexpressing of human adipose-derived mesenchymal stem cells (hADSCs) encapsulated in injectable chitosan/beta-glycerophosphate/hydroxyethylcellulose (CS/beta-GP/HEC) hydrogel for spinal cord regeneration.	beta-glycerophosphoric acid	202-223	nerve growth factor	Homo sapiens	89-92
33126695-1	2020	Thermosensitive chitosan/beta-glycerophosphate (CS/BGP) systems have been developed as injectable hydrogels.	beta-glycerophosphoric acid	25-46	citrate synthase	Homo sapiens	48-50
33713163-6	2021	RTEF-1 significantly ameliorated beta-glycerophosphate (beta-GP)-induced VSMCs calcification, as detected by alizarin red staining and calcium content assay.	beta-glycerophosphoric acid	33-54	TEA domain transcription factor 4	Homo sapiens	0-6
33501637-6	2021	Levels of CD90 were significantly decreased in the presence of liposomes filled with ascorbic acid, beta-glycerophosphate and dexamethasone (Lipo-Mix) with respect to normal differentiation medium (DM), while CD73 and CD29 expression were enhanced, suggesting osteogenic commitment.	beta-glycerophosphoric acid	100-121	Thy-1 cell surface antigen	Homo sapiens	10-14
33430198-0	2021	Influence of the Degree of Deacetylation of Chitosan and BMP-2 Concentration on Biocompatibility and Osteogenic Properties of BMP-2/PLA Granule-Loaded Chitosan/beta-Glycerophosphate Hydrogels.	beta-glycerophosphoric acid	160-181	bone morphogenetic protein 2	Rattus norvegicus	57-62
33365058-0	2021	Metformin alleviates beta-glycerophosphate-induced calcification of vascular smooth muscle cells via AMPK/mTOR-activated autophagy.	beta-glycerophosphoric acid	21-42	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	101-105
33365058-0	2021	Metformin alleviates beta-glycerophosphate-induced calcification of vascular smooth muscle cells via AMPK/mTOR-activated autophagy.	beta-glycerophosphoric acid	21-42	mechanistic target of rapamycin kinase	Homo sapiens	106-110
33365058-8	2021	The results of the present study suggested that metformin may alleviate beta-glycerophosphate-induced calcification of VSMCs, which may be attributed to the activation of AMPK/mTOR signaling pathway-dependent autophagy.	beta-glycerophosphoric acid	72-93	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	171-175
33365058-8	2021	The results of the present study suggested that metformin may alleviate beta-glycerophosphate-induced calcification of VSMCs, which may be attributed to the activation of AMPK/mTOR signaling pathway-dependent autophagy.	beta-glycerophosphoric acid	72-93	mechanistic target of rapamycin kinase	Homo sapiens	176-180
32703409-5	2020	Interestingly, five days after treatment of primary osteoblasts with ascorbic acid and beta glycerophosphate, protein levels of both DLL1 and NICD increased transiently, indicating that DLL1 activates NOTCH1 in primary cultured osteoblasts.	beta-glycerophosphoric acid	87-108	notch receptor 1	Rattus norvegicus	201-207
32202266-4	2020	We showed the feasibility of the biomimetic CAV hydrogel to induce mineralization in simulated media including simulated body fluid (SBF), glycerol phosphate calcium salt hydrate (CaGP) solution and cell co-cultured systems.	beta-glycerophosphoric acid	139-170	caveolin 2	Homo sapiens	44-47
31974677-9	2020	RESULTS: ANCR could inhibit beta-glycerophosphate (beta-GP)-induced VSMCs osteoblastic differentiation and mineralization due to decreased expressions of Runt-related transcription factor 2, bone morphogenetic protein-2, and formation of mineralized nodule, and attenuate high calcitriol-induced mice model of arterial calcification.	beta-glycerophosphoric acid	28-49	Angelman syndrome chromosome region	Homo sapiens	9-13
31974677-9	2020	RESULTS: ANCR could inhibit beta-glycerophosphate (beta-GP)-induced VSMCs osteoblastic differentiation and mineralization due to decreased expressions of Runt-related transcription factor 2, bone morphogenetic protein-2, and formation of mineralized nodule, and attenuate high calcitriol-induced mice model of arterial calcification.	beta-glycerophosphoric acid	28-49	runt related transcription factor 2	Mus musculus	154-189
31974677-9	2020	RESULTS: ANCR could inhibit beta-glycerophosphate (beta-GP)-induced VSMCs osteoblastic differentiation and mineralization due to decreased expressions of Runt-related transcription factor 2, bone morphogenetic protein-2, and formation of mineralized nodule, and attenuate high calcitriol-induced mice model of arterial calcification.	beta-glycerophosphoric acid	51-58	Angelman syndrome chromosome region	Homo sapiens	9-13
31974677-10	2020	Furthermore, ANCR could significantly increase LC3 and autophagy protein 5 expression in beta-GP-stimulated VSMCs, and the effect could be inhibited by 3-methyladenine, a pharmacological inhibitor of autophagy.	beta-glycerophosphoric acid	89-96	Angelman syndrome chromosome region	Homo sapiens	13-17
32355545-5	2020	To determine the expression of H19 in calcified VSMCs, we induced VSMCs calcification with 10 mM beta-glycerophosphate.	beta-glycerophosphoric acid	97-118	H19 imprinted maternally expressed transcript	Homo sapiens	31-34
31145871-6	2019	Compared to those of the controls, ectopic CTRP13 treatment significantly attenuated the calcium accumulation and alkaline phosphatase activity in the abdominal aorta of CRF rats, and beta-glycerophosphate induced the formation of arterial rings and of vascular smooth muscle cells (VSMCs) and decreased the number of VSMCs that transitioned from a contractile to an osteogenic phenotype.	beta-glycerophosphoric acid	184-205	complement C1q like 3	Homo sapiens	43-49
32045827-6	2020	MC3T3-E1 cells were differentiated into osteocyte-like cells (MCT3-E1-OLCs) by treatment with various agents including beta-glycerophosphate and ascorbic acid.	beta-glycerophosphoric acid	119-140	solute carrier family 16 (monocarboxylic acid transporters), member 3	Mus musculus	62-66
31831178-4	2020	Most recent observations revealed that the effect of beta-glycerophosphate on osteogenic signaling requires ORAI1, a Ca2+-channel accomplishing store-operated Ca2+-entry (SOCE), which is stimulated by Ca2+-sensor STIM1.	beta-glycerophosphoric acid	53-74	ORAI calcium release-activated calcium modulator 1	Homo sapiens	108-113
31831178-4	2020	Most recent observations revealed that the effect of beta-glycerophosphate on osteogenic signaling requires ORAI1, a Ca2+-channel accomplishing store-operated Ca2+-entry (SOCE), which is stimulated by Ca2+-sensor STIM1.	beta-glycerophosphoric acid	53-74	stromal interaction molecule 1	Homo sapiens	213-218
31831178-7	2020	As a result, 24 h exposure to beta-glycerophosphate (2 mM) significantly enhanced transcript levels of ORAI1 and STIM1 as well as SOCE, effects significantly blunted or virtually abrogated by 1.5 mM MgCl2 and by 50  muM GdCl3.	beta-glycerophosphoric acid	30-51	ORAI calcium release-activated calcium modulator 1	Homo sapiens	103-108
31831178-7	2020	As a result, 24 h exposure to beta-glycerophosphate (2 mM) significantly enhanced transcript levels of ORAI1 and STIM1 as well as SOCE, effects significantly blunted or virtually abrogated by 1.5 mM MgCl2 and by 50  muM GdCl3.	beta-glycerophosphoric acid	30-51	stromal interaction molecule 1	Homo sapiens	113-118
31831178-7	2020	As a result, 24 h exposure to beta-glycerophosphate (2 mM) significantly enhanced transcript levels of ORAI1 and STIM1 as well as SOCE, effects significantly blunted or virtually abrogated by 1.5 mM MgCl2 and by 50  muM GdCl3.	beta-glycerophosphoric acid	30-51	latexin	Homo sapiens	216-219
32015442-0	2020	Beta-Glycerophosphate-Induced ORAI1 Expression and Store Operated Ca2+ Entry in Megakaryocytes.	beta-glycerophosphoric acid	0-21	ORAI calcium release-activated calcium modulator 1	Homo sapiens	30-35
31536138-7	2020	EGR-1 siRNA decreases the bone mineralization induced by sKL or ascorbic acid/glycerol 2-phosphate in MC3T3 cells.	beta-glycerophosphoric acid	78-98	early growth response 1	Mus musculus	0-5
31920640-4	2019	In beta-glycerophosphate (beta-GP)-stimulated human aortic smooth muscle cells (HASMCs), the calcium level was increased and the expression of the calcification-related proteins OPG, OPN, Runx2, and BMP2 were all up-regulated, followed by autophagy induction and apoptosis.	beta-glycerophosphoric acid	3-24	basic transcription factor 3 pseudogene 11	Homo sapiens	178-181
31920640-4	2019	In beta-glycerophosphate (beta-GP)-stimulated human aortic smooth muscle cells (HASMCs), the calcium level was increased and the expression of the calcification-related proteins OPG, OPN, Runx2, and BMP2 were all up-regulated, followed by autophagy induction and apoptosis.	beta-glycerophosphoric acid	3-24	secreted phosphoprotein 1	Homo sapiens	183-186
31920640-4	2019	In beta-glycerophosphate (beta-GP)-stimulated human aortic smooth muscle cells (HASMCs), the calcium level was increased and the expression of the calcification-related proteins OPG, OPN, Runx2, and BMP2 were all up-regulated, followed by autophagy induction and apoptosis.	beta-glycerophosphoric acid	3-24	RUNX family transcription factor 2	Homo sapiens	188-193
31920640-4	2019	In beta-glycerophosphate (beta-GP)-stimulated human aortic smooth muscle cells (HASMCs), the calcium level was increased and the expression of the calcification-related proteins OPG, OPN, Runx2, and BMP2 were all up-regulated, followed by autophagy induction and apoptosis.	beta-glycerophosphoric acid	3-24	bone morphogenetic protein 2	Homo sapiens	199-203
31920640-4	2019	In beta-glycerophosphate (beta-GP)-stimulated human aortic smooth muscle cells (HASMCs), the calcium level was increased and the expression of the calcification-related proteins OPG, OPN, Runx2, and BMP2 were all up-regulated, followed by autophagy induction and apoptosis.	beta-glycerophosphoric acid	26-33	basic transcription factor 3 pseudogene 11	Homo sapiens	178-181
31920640-4	2019	In beta-glycerophosphate (beta-GP)-stimulated human aortic smooth muscle cells (HASMCs), the calcium level was increased and the expression of the calcification-related proteins OPG, OPN, Runx2, and BMP2 were all up-regulated, followed by autophagy induction and apoptosis.	beta-glycerophosphoric acid	26-33	secreted phosphoprotein 1	Homo sapiens	183-186
31920640-4	2019	In beta-glycerophosphate (beta-GP)-stimulated human aortic smooth muscle cells (HASMCs), the calcium level was increased and the expression of the calcification-related proteins OPG, OPN, Runx2, and BMP2 were all up-regulated, followed by autophagy induction and apoptosis.	beta-glycerophosphoric acid	26-33	RUNX family transcription factor 2	Homo sapiens	188-193
31920640-4	2019	In beta-glycerophosphate (beta-GP)-stimulated human aortic smooth muscle cells (HASMCs), the calcium level was increased and the expression of the calcification-related proteins OPG, OPN, Runx2, and BMP2 were all up-regulated, followed by autophagy induction and apoptosis.	beta-glycerophosphoric acid	26-33	bone morphogenetic protein 2	Homo sapiens	199-203
31886199-0	2019	Melatonin Attenuates beta-Glycerophosphate-Induced Calcification of Vascular Smooth Muscle Cells via a Wnt1/beta-Catenin Signaling Pathway.	beta-glycerophosphoric acid	21-42	Wnt family member 1	Homo sapiens	103-107
31886199-0	2019	Melatonin Attenuates beta-Glycerophosphate-Induced Calcification of Vascular Smooth Muscle Cells via a Wnt1/beta-Catenin Signaling Pathway.	beta-glycerophosphoric acid	21-42	catenin beta 1	Homo sapiens	108-120
31243813-9	2019	Treatment with beta-glycerophosphate (beta-GP) and ascorbic acid (A.A) enhanced osteoblastic differentiation and mineralization in Bif-1 -/- mice.	beta-glycerophosphoric acid	15-36	SH3-domain GRB2-like B1 (endophilin)	Mus musculus	131-136
31243813-9	2019	Treatment with beta-glycerophosphate (beta-GP) and ascorbic acid (A.A) enhanced osteoblastic differentiation and mineralization in Bif-1 -/- mice.	beta-glycerophosphoric acid	38-45	SH3-domain GRB2-like B1 (endophilin)	Mus musculus	131-136
31920640-5	2019	Meanwhile, we further revealed that beta-GP induced apoptosis of human osteoblasts and promoted differentiation of osteoblasts through Wnt/beta-catenin signaling.	beta-glycerophosphoric acid	36-43	catenin beta 1	Homo sapiens	139-151
31949434-4	2019	In this study, we conducted a chitosan/beta-glycerophosphate (CS/beta-GP) hydrogel as a VEGF-sustained release system and explored its effects on dental pulp stem cells (DPSCs).	beta-glycerophosphoric acid	39-60	vascular endothelial growth factor A	Homo sapiens	88-92
31829291-5	2019	Calcification induction of yVSMCs was conducted by the treatment of beta-glycerophosphate (beta-GP).	beta-glycerophosphoric acid	68-89	orosomucoid 1	Rattus norvegicus	91-98
31385016-9	2019	As a result, beta-glycerophosphate treatment increased ORAI1 and STIM1 transcript levels and protein abundance as well as SOCE in HAoSMCs.	beta-glycerophosphoric acid	13-34	ORAI calcium release-activated calcium modulator 1	Homo sapiens	55-60
31385016-9	2019	As a result, beta-glycerophosphate treatment increased ORAI1 and STIM1 transcript levels and protein abundance as well as SOCE in HAoSMCs.	beta-glycerophosphoric acid	13-34	stromal interaction molecule 1	Homo sapiens	65-70
31385016-10	2019	Additional treatment with ORAI1 inhibitor MRS1845 or SGK1 inhibitor GSK650394 virtually disrupted the effects of beta-glycerophosphate on SOCE.	beta-glycerophosphoric acid	113-134	ORAI calcium release-activated calcium modulator 1	Homo sapiens	26-31
31385016-10	2019	Additional treatment with ORAI1 inhibitor MRS1845 or SGK1 inhibitor GSK650394 virtually disrupted the effects of beta-glycerophosphate on SOCE.	beta-glycerophosphoric acid	113-134	serum/glucocorticoid regulated kinase 1	Homo sapiens	53-57
31385016-11	2019	Moreover, the beta-glycerophosphate-induced MSX2, CBFA1, SOX9, and ALPL mRNA expression and activity in HAoSMCs were suppressed in the presence of the ORAI1 inhibitor and upon ORAI1 silencing.	beta-glycerophosphoric acid	14-35	msh homeobox 2	Homo sapiens	44-48
31385016-11	2019	Moreover, the beta-glycerophosphate-induced MSX2, CBFA1, SOX9, and ALPL mRNA expression and activity in HAoSMCs were suppressed in the presence of the ORAI1 inhibitor and upon ORAI1 silencing.	beta-glycerophosphoric acid	14-35	RUNX family transcription factor 2	Homo sapiens	50-55
31385016-11	2019	Moreover, the beta-glycerophosphate-induced MSX2, CBFA1, SOX9, and ALPL mRNA expression and activity in HAoSMCs were suppressed in the presence of the ORAI1 inhibitor and upon ORAI1 silencing.	beta-glycerophosphoric acid	14-35	SRY-box transcription factor 9	Homo sapiens	57-61
31385016-11	2019	Moreover, the beta-glycerophosphate-induced MSX2, CBFA1, SOX9, and ALPL mRNA expression and activity in HAoSMCs were suppressed in the presence of the ORAI1 inhibitor and upon ORAI1 silencing.	beta-glycerophosphoric acid	14-35	alkaline phosphatase, biomineralization associated	Homo sapiens	67-71
31385016-11	2019	Moreover, the beta-glycerophosphate-induced MSX2, CBFA1, SOX9, and ALPL mRNA expression and activity in HAoSMCs were suppressed in the presence of the ORAI1 inhibitor and upon ORAI1 silencing.	beta-glycerophosphoric acid	14-35	ORAI calcium release-activated calcium modulator 1	Homo sapiens	151-156
31385016-11	2019	Moreover, the beta-glycerophosphate-induced MSX2, CBFA1, SOX9, and ALPL mRNA expression and activity in HAoSMCs were suppressed in the presence of the ORAI1 inhibitor and upon ORAI1 silencing.	beta-glycerophosphoric acid	14-35	ORAI calcium release-activated calcium modulator 1	Homo sapiens	176-181
31502564-0	2019	Adiponectin inhibits vascular smooth muscle cell calcification induced by beta-glycerophosphate through JAK2/STAT3 signaling pathway.	beta-glycerophosphoric acid	74-95	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
31502564-0	2019	Adiponectin inhibits vascular smooth muscle cell calcification induced by beta-glycerophosphate through JAK2/STAT3 signaling pathway.	beta-glycerophosphoric acid	74-95	Janus kinase 2	Homo sapiens	104-108
31502564-0	2019	Adiponectin inhibits vascular smooth muscle cell calcification induced by beta-glycerophosphate through JAK2/STAT3 signaling pathway.	beta-glycerophosphoric acid	74-95	signal transducer and activator of transcription 3	Homo sapiens	109-114
31502564-4	2019	This study aims to explore the effect of APN on vascular calcification by using a cell model induced by beta-glycerophosphate (beta-GP).	beta-glycerophosphoric acid	104-125	adiponectin, C1Q and collagen domain containing	Homo sapiens	41-44
31502564-4	2019	This study aims to explore the effect of APN on vascular calcification by using a cell model induced by beta-glycerophosphate (beta-GP).	beta-glycerophosphoric acid	127-134	adiponectin, C1Q and collagen domain containing	Homo sapiens	41-44
31354482-8	2019	CA1 was also highly expressed in human AS tissues and in rat vascular smooth muscle cells (VSMCs) with beta-glycerophosphate ( beta-GP)-induced calcification.	beta-glycerophosphoric acid	103-124	carbonic anhydrase 1	Homo sapiens	0-3
31354482-8	2019	CA1 was also highly expressed in human AS tissues and in rat vascular smooth muscle cells (VSMCs) with beta-glycerophosphate ( beta-GP)-induced calcification.	beta-glycerophosphoric acid	127-134	carbonic anhydrase 1	Homo sapiens	0-3
31212828-5	2019	Upon stimulation in osteogenic medium containing 50 mug/mL of ascorbic acid (AA) and 7.5 mM of beta-glycerophosphate (beta-GP), human osteosarcoma Saos-2 cells initiated mineralization, as evidenced by Alizarin Red-S (AR-S) staining, TNAP activity, and the partial translocation of AnxA6 from cytoplasm to the plasma membrane.	beta-glycerophosphoric acid	95-116	secreted LY6/PLAUR domain containing 1	Homo sapiens	218-222
30829051-8	2019	Upregulation of PGC-1alpha inhibited, whereas PGC-1alpha depletion promoted beta-glycerophosphate-induced mtROS production and calcium deposition.	beta-glycerophosphoric acid	76-97	PPARG coactivator 1 alpha	Homo sapiens	46-56
31004580-9	2019	TNAP activity in calcifying VSMCs was ~100-fold lower than that of bone-forming osteoblasts and cultures treated with beta-glycerophosphate, a TNAP substrate, did not calcify.	beta-glycerophosphoric acid	118-139	alkaline phosphatase, liver/bone/kidney	Mus musculus	0-4
31004580-9	2019	TNAP activity in calcifying VSMCs was ~100-fold lower than that of bone-forming osteoblasts and cultures treated with beta-glycerophosphate, a TNAP substrate, did not calcify.	beta-glycerophosphoric acid	118-139	alkaline phosphatase, liver/bone/kidney	Mus musculus	143-147
31212828-5	2019	Upon stimulation in osteogenic medium containing 50 mug/mL of ascorbic acid (AA) and 7.5 mM of beta-glycerophosphate (beta-GP), human osteosarcoma Saos-2 cells initiated mineralization, as evidenced by Alizarin Red-S (AR-S) staining, TNAP activity, and the partial translocation of AnxA6 from cytoplasm to the plasma membrane.	beta-glycerophosphoric acid	95-116	annexin A6	Homo sapiens	282-287
30271655-4	2018	Cultured mouse C2C12 cells were treated with 10 mM beta-glycerophosphate (BGP] at different periods of time to induce hyperphosphatemia.	beta-glycerophosphoric acid	51-72	carcinoembryonic antigen-related cell adhesion molecule 1	Mus musculus	74-77
30207376-6	2019	We observed an early increase in PLD1 gene and protein expression along with the increase in the PLD activity in vascular muscle cell line, during calcification induced by ascorbic acid and beta-glycerophosphate.	beta-glycerophosphoric acid	190-211	phospholipase D1	Rattus norvegicus	33-37
30170182-8	2019	More importantly, enhanced mitochondrial biogenesis attenuated the beta-GP-induced phenotypic transformation of VSMCs into an osteogenic phenotype through inhibition of the PDK4/oxidative stress-mediated apoptosis pathway, whereas disruption of mitochondrial biogenesis by zidovudine aggravated beta-GP-induced apoptosis in VSMCs.	beta-glycerophosphoric acid	67-74	pyruvate dehydrogenase kinase 4	Homo sapiens	173-177
30607145-1	2018	Erythropoietin (EPO) was successfully incorporated into a bioadhesive thermosensitive hydrogel based on trimethyl chitosan (TMC)/beta-glycerophosphate (GP) for prevention and treatment of oral mucositis in cancerous patients.	beta-glycerophosphoric acid	129-150	erythropoietin	Homo sapiens	0-14
30607145-1	2018	Erythropoietin (EPO) was successfully incorporated into a bioadhesive thermosensitive hydrogel based on trimethyl chitosan (TMC)/beta-glycerophosphate (GP) for prevention and treatment of oral mucositis in cancerous patients.	beta-glycerophosphoric acid	129-150	erythropoietin	Homo sapiens	16-19
30607145-1	2018	Erythropoietin (EPO) was successfully incorporated into a bioadhesive thermosensitive hydrogel based on trimethyl chitosan (TMC)/beta-glycerophosphate (GP) for prevention and treatment of oral mucositis in cancerous patients.	beta-glycerophosphoric acid	152-154	erythropoietin	Homo sapiens	0-14
30607145-1	2018	Erythropoietin (EPO) was successfully incorporated into a bioadhesive thermosensitive hydrogel based on trimethyl chitosan (TMC)/beta-glycerophosphate (GP) for prevention and treatment of oral mucositis in cancerous patients.	beta-glycerophosphoric acid	152-154	erythropoietin	Homo sapiens	16-19
29895327-4	2018	Here, we demonstrate that MSC-CM inhibits beta-glycerophosphate (beta-GP)-induced vascular calcification through blockade of the bone morphogenetic protein-2 (BMP2)-Smad1/5/8 signaling pathway.	beta-glycerophosphoric acid	42-63	bone morphogenetic protein 2	Homo sapiens	129-157
29932916-4	2018	FGF21 inhibited beta-glycerophosphate (BGP) induced mineralization in VSMCs as determined by calcium concentration and Alizarin Red S. FGF21 suppressed BGP-induced BMP2/Smad signaling pathway components as well as osteoblast differentiation markers.	beta-glycerophosphoric acid	16-37	fibroblast growth factor 21	Homo sapiens	0-5
29932916-4	2018	FGF21 inhibited beta-glycerophosphate (BGP) induced mineralization in VSMCs as determined by calcium concentration and Alizarin Red S. FGF21 suppressed BGP-induced BMP2/Smad signaling pathway components as well as osteoblast differentiation markers.	beta-glycerophosphoric acid	16-37	fibroblast growth factor 21	Homo sapiens	135-140
29932916-4	2018	FGF21 inhibited beta-glycerophosphate (BGP) induced mineralization in VSMCs as determined by calcium concentration and Alizarin Red S. FGF21 suppressed BGP-induced BMP2/Smad signaling pathway components as well as osteoblast differentiation markers.	beta-glycerophosphoric acid	16-37	bone morphogenetic protein 2	Homo sapiens	164-168
29932916-4	2018	FGF21 inhibited beta-glycerophosphate (BGP) induced mineralization in VSMCs as determined by calcium concentration and Alizarin Red S. FGF21 suppressed BGP-induced BMP2/Smad signaling pathway components as well as osteoblast differentiation markers.	beta-glycerophosphoric acid	39-42	fibroblast growth factor 21	Homo sapiens	0-5
29932916-4	2018	FGF21 inhibited beta-glycerophosphate (BGP) induced mineralization in VSMCs as determined by calcium concentration and Alizarin Red S. FGF21 suppressed BGP-induced BMP2/Smad signaling pathway components as well as osteoblast differentiation markers.	beta-glycerophosphoric acid	39-42	fibroblast growth factor 21	Homo sapiens	135-140
29932916-4	2018	FGF21 inhibited beta-glycerophosphate (BGP) induced mineralization in VSMCs as determined by calcium concentration and Alizarin Red S. FGF21 suppressed BGP-induced BMP2/Smad signaling pathway components as well as osteoblast differentiation markers.	beta-glycerophosphoric acid	39-42	bone morphogenetic protein 2	Homo sapiens	164-168
29851201-10	2018	In addition, beta-GP induced increased expression of P-GSK-3beta/GSK-3beta and c-myc, which were all downregulated in the beta-GP + Klotho group.	beta-glycerophosphoric acid	13-20	glycogen synthase kinase 3 beta	Rattus norvegicus	55-64
29851201-10	2018	In addition, beta-GP induced increased expression of P-GSK-3beta/GSK-3beta and c-myc, which were all downregulated in the beta-GP + Klotho group.	beta-glycerophosphoric acid	13-20	glycogen synthase kinase 3 beta	Rattus norvegicus	65-74
29851201-10	2018	In addition, beta-GP induced increased expression of P-GSK-3beta/GSK-3beta and c-myc, which were all downregulated in the beta-GP + Klotho group.	beta-glycerophosphoric acid	13-20	MYC proto-oncogene, bHLH transcription factor	Rattus norvegicus	79-84
29851201-10	2018	In addition, beta-GP induced increased expression of P-GSK-3beta/GSK-3beta and c-myc, which were all downregulated in the beta-GP + Klotho group.	beta-glycerophosphoric acid	13-20	Klotho	Rattus norvegicus	132-138
29436118-7	2018	In a rat cultured vascular smooth muscular cell (VSMC) calcification model induced by beta-glycerophosphate (beta-GP), CST inhibited the increase in ALP activity, calcium content and OCN protein and the decrease in SM-alpha-actin expression.	beta-glycerophosphoric acid	86-107	cortistatin	Rattus norvegicus	119-122
29436118-7	2018	In a rat cultured vascular smooth muscular cell (VSMC) calcification model induced by beta-glycerophosphate (beta-GP), CST inhibited the increase in ALP activity, calcium content and OCN protein and the decrease in SM-alpha-actin expression.	beta-glycerophosphoric acid	109-116	cortistatin	Rattus norvegicus	119-122
29895327-4	2018	Here, we demonstrate that MSC-CM inhibits beta-glycerophosphate (beta-GP)-induced vascular calcification through blockade of the bone morphogenetic protein-2 (BMP2)-Smad1/5/8 signaling pathway.	beta-glycerophosphoric acid	42-63	bone morphogenetic protein 2	Homo sapiens	159-163
29895327-4	2018	Here, we demonstrate that MSC-CM inhibits beta-glycerophosphate (beta-GP)-induced vascular calcification through blockade of the bone morphogenetic protein-2 (BMP2)-Smad1/5/8 signaling pathway.	beta-glycerophosphoric acid	42-63	SMAD family member 1	Homo sapiens	165-172
29895327-4	2018	Here, we demonstrate that MSC-CM inhibits beta-glycerophosphate (beta-GP)-induced vascular calcification through blockade of the bone morphogenetic protein-2 (BMP2)-Smad1/5/8 signaling pathway.	beta-glycerophosphoric acid	65-72	bone morphogenetic protein 2	Homo sapiens	129-157
29895327-4	2018	Here, we demonstrate that MSC-CM inhibits beta-glycerophosphate (beta-GP)-induced vascular calcification through blockade of the bone morphogenetic protein-2 (BMP2)-Smad1/5/8 signaling pathway.	beta-glycerophosphoric acid	65-72	bone morphogenetic protein 2	Homo sapiens	159-163
29895327-4	2018	Here, we demonstrate that MSC-CM inhibits beta-glycerophosphate (beta-GP)-induced vascular calcification through blockade of the bone morphogenetic protein-2 (BMP2)-Smad1/5/8 signaling pathway.	beta-glycerophosphoric acid	65-72	SMAD family member 1	Homo sapiens	165-172
29391410-9	2018	beta-glycerophosphate increased expression of osteopontin but no other genes related to calcification.	beta-glycerophosphoric acid	0-21	secreted phosphoprotein 1	Bos taurus	46-57
29442285-13	2018	beta-glycerophosphate, was identified interacting with BMP-2 in a synergistic manner.	beta-glycerophosphoric acid	0-21	bone morphogenetic protein 2	Homo sapiens	55-60
29138798-4	2018	The results of the study demonstrated that Hey1 expression in odontoblast-lineage cells (OLCs) was upregulated by stimulation of osteoblastic/odontoblastic differentiation medium containing ascorbic acid, beta-glycerol phosphate and dexamethasone.	beta-glycerophosphoric acid	205-228	hes related family bHLH transcription factor with YRPW motif 1	Homo sapiens	43-47
28857396-3	2017	The phosphate donor beta-glycerophosphate (BGP) in human endothelial cells increased ET-1 production, endothelin-converting enzyme-1 (ECE-1) protein, and mRNA expression, which depend on the AP-1 activation through ROS production.	beta-glycerophosphoric acid	20-41	endothelin 1	Homo sapiens	85-89
28857396-3	2017	The phosphate donor beta-glycerophosphate (BGP) in human endothelial cells increased ET-1 production, endothelin-converting enzyme-1 (ECE-1) protein, and mRNA expression, which depend on the AP-1 activation through ROS production.	beta-glycerophosphoric acid	20-41	endothelin converting enzyme 1	Homo sapiens	102-132
28857396-3	2017	The phosphate donor beta-glycerophosphate (BGP) in human endothelial cells increased ET-1 production, endothelin-converting enzyme-1 (ECE-1) protein, and mRNA expression, which depend on the AP-1 activation through ROS production.	beta-glycerophosphoric acid	20-41	endothelin converting enzyme 1	Homo sapiens	134-139
28857396-3	2017	The phosphate donor beta-glycerophosphate (BGP) in human endothelial cells increased ET-1 production, endothelin-converting enzyme-1 (ECE-1) protein, and mRNA expression, which depend on the AP-1 activation through ROS production.	beta-glycerophosphoric acid	43-46	endothelin 1	Homo sapiens	85-89
28857396-3	2017	The phosphate donor beta-glycerophosphate (BGP) in human endothelial cells increased ET-1 production, endothelin-converting enzyme-1 (ECE-1) protein, and mRNA expression, which depend on the AP-1 activation through ROS production.	beta-glycerophosphoric acid	43-46	endothelin converting enzyme 1	Homo sapiens	102-132
28857396-3	2017	The phosphate donor beta-glycerophosphate (BGP) in human endothelial cells increased ET-1 production, endothelin-converting enzyme-1 (ECE-1) protein, and mRNA expression, which depend on the AP-1 activation through ROS production.	beta-glycerophosphoric acid	43-46	endothelin converting enzyme 1	Homo sapiens	134-139
29182679-7	2017	When murine calvaria-derived MC3T3-E1 cells were cultured in osteogenic medium containing 50 mug/ml ascorbic acid and 5 mM beta-glycerophosphate, Edil3 mRNA and protein expression levels were increased.	beta-glycerophosphoric acid	123-144	EGF-like repeats and discoidin I-like domains 3	Mus musculus	146-151
28860220-15	2017	IL-18 enhances VSMCs osteogenic differentiation and subsequent VC induced by beta-glycerophosphate via TRPM7 channel activation.	beta-glycerophosphoric acid	77-98	interleukin 18	Homo sapiens	0-5
29016732-4	2017	Methods and results: We demonstrate that FGF-2 expression is increased in vascular smooth muscle cells (VSMCs) induced to deposit a mineralized matrix by incubation with beta-glycerophosphate.	beta-glycerophosphoric acid	170-191	fibroblast growth factor 2	Homo sapiens	41-46
28860220-15	2017	IL-18 enhances VSMCs osteogenic differentiation and subsequent VC induced by beta-glycerophosphate via TRPM7 channel activation.	beta-glycerophosphoric acid	77-98	transient receptor potential cation channel subfamily M member 7	Homo sapiens	103-108
29050490-4	2017	After beta-GP treatment, beta-GP promoted clear mineralized nodule changes, and miR-26a and OPG expression were significantly decreased and CTGF, RANKL and ALP expression were increased in VSMCs.	beta-glycerophosphoric acid	6-13	microRNA 26a-1	Homo sapiens	80-87
28497879-4	2017	Pre-osteoblasts exposed to osteogenic media (ascorbic acid, 50 microg/ml and beta-glycerophosphate, 10 mM) showed high protein expression of BMP-5 in cell lysates and cell culture supernatants, which peaked during early time-points of differentiation and declined with onset of mineralization.	beta-glycerophosphoric acid	77-98	bone morphogenetic protein 5	Mus musculus	141-146
28525946-13	2017	From in vitro investigation, we found that the high-glucose (HG), high-lipid (HL), and beta-glycerophosphate (beta-GP) considerably increased the total calcium content, ALP activity, and expression of osteogenic markers in vascular smooth muscle cells (VSMCs).	beta-glycerophosphoric acid	87-108	ATHS	Homo sapiens	169-172
28525946-13	2017	From in vitro investigation, we found that the high-glucose (HG), high-lipid (HL), and beta-glycerophosphate (beta-GP) considerably increased the total calcium content, ALP activity, and expression of osteogenic markers in vascular smooth muscle cells (VSMCs).	beta-glycerophosphoric acid	110-117	ATHS	Homo sapiens	169-172
29050490-4	2017	After beta-GP treatment, beta-GP promoted clear mineralized nodule changes, and miR-26a and OPG expression were significantly decreased and CTGF, RANKL and ALP expression were increased in VSMCs.	beta-glycerophosphoric acid	6-13	cellular communication network factor 2	Homo sapiens	140-144
29050490-4	2017	After beta-GP treatment, beta-GP promoted clear mineralized nodule changes, and miR-26a and OPG expression were significantly decreased and CTGF, RANKL and ALP expression were increased in VSMCs.	beta-glycerophosphoric acid	6-13	TNF superfamily member 11	Homo sapiens	146-151
27480534-6	2016	After incubating rat and human VSMCs with beta-GP in the presence of different doses of CST (10-8 or 10-7 mol/L), CST clearly reversed the beta-GP-induced increases in ALP activity and calcium content and formation of pathological calcified nodes of VSMCs in a dose-independent manner.	beta-glycerophosphoric acid	42-49	cortistatin	Homo sapiens	88-91
27480534-6	2016	After incubating rat and human VSMCs with beta-GP in the presence of different doses of CST (10-8 or 10-7 mol/L), CST clearly reversed the beta-GP-induced increases in ALP activity and calcium content and formation of pathological calcified nodes of VSMCs in a dose-independent manner.	beta-glycerophosphoric acid	42-49	cortistatin	Homo sapiens	114-117
27480534-6	2016	After incubating rat and human VSMCs with beta-GP in the presence of different doses of CST (10-8 or 10-7 mol/L), CST clearly reversed the beta-GP-induced increases in ALP activity and calcium content and formation of pathological calcified nodes of VSMCs in a dose-independent manner.	beta-glycerophosphoric acid	42-49	alkaline phosphatase, placental	Homo sapiens	168-171
27480534-6	2016	After incubating rat and human VSMCs with beta-GP in the presence of different doses of CST (10-8 or 10-7 mol/L), CST clearly reversed the beta-GP-induced increases in ALP activity and calcium content and formation of pathological calcified nodes of VSMCs in a dose-independent manner.	beta-glycerophosphoric acid	139-146	cortistatin	Homo sapiens	88-91
27480534-6	2016	After incubating rat and human VSMCs with beta-GP in the presence of different doses of CST (10-8 or 10-7 mol/L), CST clearly reversed the beta-GP-induced increases in ALP activity and calcium content and formation of pathological calcified nodes of VSMCs in a dose-independent manner.	beta-glycerophosphoric acid	139-146	cortistatin	Homo sapiens	114-117
27480534-6	2016	After incubating rat and human VSMCs with beta-GP in the presence of different doses of CST (10-8 or 10-7 mol/L), CST clearly reversed the beta-GP-induced increases in ALP activity and calcium content and formation of pathological calcified nodes of VSMCs in a dose-independent manner.	beta-glycerophosphoric acid	139-146	alkaline phosphatase, placental	Homo sapiens	168-171
27496540-13	2016	Dental pulp stem cells seeded in chitosan/beta-glycerophosphate/hydroxyapatite hydrogels had a higher alkaline phosphatase activity and better up-regulation of gene expression levels of Runx-2, Collagen I, alkaline phosphatase and osteocalcin than in chitosan /beta-glycerophosphate hydrogels after osteogenic differentiation.	beta-glycerophosphoric acid	42-63	RUNX family transcription factor 2	Homo sapiens	186-192
27496540-13	2016	Dental pulp stem cells seeded in chitosan/beta-glycerophosphate/hydroxyapatite hydrogels had a higher alkaline phosphatase activity and better up-regulation of gene expression levels of Runx-2, Collagen I, alkaline phosphatase and osteocalcin than in chitosan /beta-glycerophosphate hydrogels after osteogenic differentiation.	beta-glycerophosphoric acid	42-63	bone gamma-carboxyglutamate protein	Homo sapiens	231-242
25729272-7	2015	After 4 weeks of treatment in HG group containing beta-GP and rhBMP-7, an inhibitor of vascular calcification, OPG expressions were maintained.	beta-glycerophosphoric acid	50-57	TNF receptor superfamily member 11B	Rattus norvegicus	111-114
25702817-9	2016	Furthermore, PRP stimulated the ALP activity and mineralized nodule formation induced by ascorbic acid and beta-glycerophosphate in a time-dependent manner.	beta-glycerophosphoric acid	107-128	prion protein	Homo sapiens	13-16
25702817-9	2016	Furthermore, PRP stimulated the ALP activity and mineralized nodule formation induced by ascorbic acid and beta-glycerophosphate in a time-dependent manner.	beta-glycerophosphoric acid	107-128	alkaline phosphatase, placental	Homo sapiens	32-35
27346269-9	2016	CONCLUSION: KCa3.1 blocker TRAM-34 can inhibit beta-glycerophosphate induced VSMCs and aortic ring calcification through inhibiting calcium influx, downregulating Runx2 expression and attenuating osteogenic differentiation.	beta-glycerophosphoric acid	47-68	potassium calcium-activated channel subfamily N member 4	Rattus norvegicus	12-18
26467393-4	2015	Human aortic smooth muscle cells treated with beta-Glycerophosphate (BGP, 10mM) suffered cellular senescence by increasing p53, p21 and p16 expression and the senescence associated beta-galactosidase activity.	beta-glycerophosphoric acid	46-67	tumor protein p53	Homo sapiens	123-126
26467393-4	2015	Human aortic smooth muscle cells treated with beta-Glycerophosphate (BGP, 10mM) suffered cellular senescence by increasing p53, p21 and p16 expression and the senescence associated beta-galactosidase activity.	beta-glycerophosphoric acid	46-67	H3 histone pseudogene 16	Homo sapiens	128-131
26467393-4	2015	Human aortic smooth muscle cells treated with beta-Glycerophosphate (BGP, 10mM) suffered cellular senescence by increasing p53, p21 and p16 expression and the senescence associated beta-galactosidase activity.	beta-glycerophosphoric acid	46-67	cyclin dependent kinase inhibitor 2A	Homo sapiens	136-139
26467393-4	2015	Human aortic smooth muscle cells treated with beta-Glycerophosphate (BGP, 10mM) suffered cellular senescence by increasing p53, p21 and p16 expression and the senescence associated beta-galactosidase activity.	beta-glycerophosphoric acid	46-67	galactosidase beta 1	Homo sapiens	181-199
26168053-7	2015	Although no significant differences were detected among media for human BMSCs, beta-GlyP with or without BMP-2 determined a positive trend in ALP levels compared to NaH2PO4.	beta-glycerophosphoric acid	79-88	alkaline phosphatase, placental	Homo sapiens	142-145
26168053-9	2015	beta-GlyP better supported the expression of COL1A1 in human BMSCs, whereas all media enhanced RUNX2 and SPARC expression.	beta-glycerophosphoric acid	0-9	collagen type I alpha 1 chain	Homo sapiens	45-51
26955732-9	2015	CONCLUSION: Human BMP-2, beta-glycerophosphate, L-ascorbic acid, and dexamethasone can induce human heart valve interstitial cells calcification and enhance inflammation in vitro by stimulating the secretion of BMP-2.	beta-glycerophosphoric acid	25-46	bone morphogenetic protein 2	Homo sapiens	211-216
26221600-6	2015	Furthermore, overexpression of Runx2 induces miR-2861 and miR-3960 transcription, and knockdown of Runx2 attenuates beta-glycerophosphate-induced miR-2861 and miR-3960 transcription in VSMCs.	beta-glycerophosphoric acid	116-137	RUNX family transcription factor 2	Homo sapiens	99-104
26221600-6	2015	Furthermore, overexpression of Runx2 induces miR-2861 and miR-3960 transcription, and knockdown of Runx2 attenuates beta-glycerophosphate-induced miR-2861 and miR-3960 transcription in VSMCs.	beta-glycerophosphoric acid	116-137	microRNA 2861	Homo sapiens	146-154
26221600-3	2015	Our recent study showed that miR-2861 and miR-3960 expression increases significantly during beta-glycerophosphate-induced osteogenic transdifferentiation of VSMCs.	beta-glycerophosphoric acid	93-114	microRNA 2861	Homo sapiens	29-37
26221600-6	2015	Furthermore, overexpression of Runx2 induces miR-2861 and miR-3960 transcription, and knockdown of Runx2 attenuates beta-glycerophosphate-induced miR-2861 and miR-3960 transcription in VSMCs.	beta-glycerophosphoric acid	116-137	microRNA 3960	Homo sapiens	159-167
26221600-3	2015	Our recent study showed that miR-2861 and miR-3960 expression increases significantly during beta-glycerophosphate-induced osteogenic transdifferentiation of VSMCs.	beta-glycerophosphoric acid	93-114	microRNA 3960	Homo sapiens	42-50
24793006-9	2014	Reciprocally, MBG reduced runt-related transcription factor 2 (RunX2) expression, which resulted in the inhibition of osteogenesis induced by beta-glycerophosphate/ascorbic acid.	beta-glycerophosphoric acid	142-163	runt related transcription factor 2	Mus musculus	26-61
26221600-4	2015	Overexpression of miR-2861 or miR-3960 in VSMCs enhances beta-glycerophosphate-induced osteoblastogenesis, whereas inhibition of miR-2861 or miR-3960 expression attenuates it.	beta-glycerophosphoric acid	57-78	microRNA 2861	Homo sapiens	18-26
26221600-4	2015	Overexpression of miR-2861 or miR-3960 in VSMCs enhances beta-glycerophosphate-induced osteoblastogenesis, whereas inhibition of miR-2861 or miR-3960 expression attenuates it.	beta-glycerophosphoric acid	57-78	microRNA 3960	Homo sapiens	30-38
24906729-4	2014	The CS-TBA/HA/beta-GP gel showed a higher storage modulus (G") and loss modulus (G"") and a decreased bovine serum albumin (BSA) release rate which was maintained the protein release for a longer time compared with the unmodified chitosan (CS)/HA/beta-GP gel, due to the existence of thiol groups and/or disulfide bonds.	beta-glycerophosphoric acid	14-21	albumin	Homo sapiens	109-122
25015959-4	2014	TNAP activity was enhanced by injection of Zn acetate into a tail vein before harvesting the heart and imaged using electron microscopy of electron dense deposits indicative of the hydrolysis of exogenous beta-glycerophosphate.	beta-glycerophosphoric acid	205-226	alkaline phosphatase, biomineralization associated	Rattus norvegicus	0-4
25458345-9	2014	The findings suggest the combined addition of BMP-2, BMP-6 and BMP-9 to the osteoinductive culture medium containing dexamethasone, beta-glycerophosphate and ascorbate-2-phosphate produces more potent osteoblast differentiation of human MSCs in vitro.	beta-glycerophosphoric acid	132-153	bone morphogenetic protein 2	Homo sapiens	46-51
25458345-9	2014	The findings suggest the combined addition of BMP-2, BMP-6 and BMP-9 to the osteoinductive culture medium containing dexamethasone, beta-glycerophosphate and ascorbate-2-phosphate produces more potent osteoblast differentiation of human MSCs in vitro.	beta-glycerophosphoric acid	132-153	bone morphogenetic protein 6	Homo sapiens	53-58
25458345-9	2014	The findings suggest the combined addition of BMP-2, BMP-6 and BMP-9 to the osteoinductive culture medium containing dexamethasone, beta-glycerophosphate and ascorbate-2-phosphate produces more potent osteoblast differentiation of human MSCs in vitro.	beta-glycerophosphoric acid	132-153	growth differentiation factor 2	Homo sapiens	63-68
25407893-9	2014	RESULTS: Exenatide, an agonist of GLP-1 receptor, attenuated beta-glycerol phosphate (beta-GP) induced osteoblastic differentiation and calcification of human CVSMCs in a dose- and time-dependent manner.	beta-glycerophosphoric acid	61-84	glucagon like peptide 1 receptor	Homo sapiens	34-48
25407893-9	2014	RESULTS: Exenatide, an agonist of GLP-1 receptor, attenuated beta-glycerol phosphate (beta-GP) induced osteoblastic differentiation and calcification of human CVSMCs in a dose- and time-dependent manner.	beta-glycerophosphoric acid	86-93	glucagon like peptide 1 receptor	Homo sapiens	34-48
24793006-9	2014	Reciprocally, MBG reduced runt-related transcription factor 2 (RunX2) expression, which resulted in the inhibition of osteogenesis induced by beta-glycerophosphate/ascorbic acid.	beta-glycerophosphoric acid	142-163	runt related transcription factor 2	Mus musculus	63-68
24486760-13	2014	CONCLUSION: Our study suggests that down-regulation of miR-125b after beta-glycerophosphoric acid treatment facilitates VSMCs transdifferentiation and calcification through targeting Ets1.	beta-glycerophosphoric acid	70-97	ETS proto-oncogene 1, transcription factor	Homo sapiens	183-187
24607448-11	2014	Adiponectin upregulated TSC2 expression and downregulated mTOR and S6K1 phosphorylation in beta-GP-treated VSMCs.	beta-glycerophosphoric acid	91-98	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
24607448-11	2014	Adiponectin upregulated TSC2 expression and downregulated mTOR and S6K1 phosphorylation in beta-GP-treated VSMCs.	beta-glycerophosphoric acid	91-98	mechanistic target of rapamycin kinase	Homo sapiens	58-62
24607448-11	2014	Adiponectin upregulated TSC2 expression and downregulated mTOR and S6K1 phosphorylation in beta-GP-treated VSMCs.	beta-glycerophosphoric acid	91-98	ribosomal protein S6 kinase B1	Homo sapiens	67-71
24486760-6	2014	In VSMCs, after beta-glycerophosphoric acid treatment, the expressions of cbf beta1, osteocalcin and osteopontin were significantly increased and SM-22beta expression was decreased.	beta-glycerophosphoric acid	16-43	bone gamma-carboxyglutamate protein	Homo sapiens	85-96
24486760-6	2014	In VSMCs, after beta-glycerophosphoric acid treatment, the expressions of cbf beta1, osteocalcin and osteopontin were significantly increased and SM-22beta expression was decreased.	beta-glycerophosphoric acid	16-43	secreted phosphoprotein 1	Homo sapiens	101-112
25012146-5	2014	RESULTS: The expression of endogenous miR-205 was decreased in HASMCs during beta-glycerophosphate-induced calcification.	beta-glycerophosphoric acid	77-98	microRNA 205	Homo sapiens	38-45
24486760-12	2014	Downregulating Ets1 expression by its siRNA inhibited beta-glycerophosphoric acid-induced the VSMCs phenotypic transition and calcification.	beta-glycerophosphoric acid	54-81	ETS proto-oncogene 1, transcription factor	Homo sapiens	15-19
25012146-8	2014	CONCLUSION: The present study shows that miR-205 may negatively regulate the beta-glycerophosphate-induced calcification of HASMCs, at least partially by targeting Runx2 and Smad1.	beta-glycerophosphoric acid	77-98	microRNA 205	Homo sapiens	41-48
25012146-8	2014	CONCLUSION: The present study shows that miR-205 may negatively regulate the beta-glycerophosphate-induced calcification of HASMCs, at least partially by targeting Runx2 and Smad1.	beta-glycerophosphoric acid	77-98	RUNX family transcription factor 2	Homo sapiens	164-169
25012146-8	2014	CONCLUSION: The present study shows that miR-205 may negatively regulate the beta-glycerophosphate-induced calcification of HASMCs, at least partially by targeting Runx2 and Smad1.	beta-glycerophosphoric acid	77-98	SMAD family member 1	Homo sapiens	174-179
24319708-3	2013	The maximum transcription of BMP-2 gene and genes of osteogenic markers (bone sialoprotein, osteopontin, and osteocalcin) was observed in the medium containing sodium beta-glycerophosphate and ascorbic acid.	beta-glycerophosphoric acid	160-188	bone morphogenetic protein 2	Homo sapiens	29-34
24319708-3	2013	The maximum transcription of BMP-2 gene and genes of osteogenic markers (bone sialoprotein, osteopontin, and osteocalcin) was observed in the medium containing sodium beta-glycerophosphate and ascorbic acid.	beta-glycerophosphoric acid	160-188	secreted phosphoprotein 1	Homo sapiens	92-103
24319708-3	2013	The maximum transcription of BMP-2 gene and genes of osteogenic markers (bone sialoprotein, osteopontin, and osteocalcin) was observed in the medium containing sodium beta-glycerophosphate and ascorbic acid.	beta-glycerophosphoric acid	160-188	bone gamma-carboxyglutamate protein	Homo sapiens	109-120
24026476-4	2013	In contrast, the addition of FGF7 facilitated the dexamethasone, ascorbic acid, and beta-glycerophosphate (DAG)-induced increases in bone-like nodule formation and calcium accumulation.	beta-glycerophosphoric acid	84-105	fibroblast growth factor 7	Mus musculus	29-33
24025223-3	2013	In female rat aortic smooth muscle cells (RASMCs), we observed that metformin significantly alleviated beta-glycerophosphate-induced Ca deposition and alkaline phosphatase activity, corresponding with reduced expression of some specific genes in osteoblast-like cells, including Runx2 and bone morphogenetic protein-2, and positive effects on alpha-actin expression, a specific marker of smooth muscle cells.	beta-glycerophosphoric acid	103-124	RUNX family transcription factor 2	Rattus norvegicus	279-284
24025223-3	2013	In female rat aortic smooth muscle cells (RASMCs), we observed that metformin significantly alleviated beta-glycerophosphate-induced Ca deposition and alkaline phosphatase activity, corresponding with reduced expression of some specific genes in osteoblast-like cells, including Runx2 and bone morphogenetic protein-2, and positive effects on alpha-actin expression, a specific marker of smooth muscle cells.	beta-glycerophosphoric acid	103-124	bone morphogenetic protein 2	Rattus norvegicus	289-317
23312504-8	2013	Beta-glycerophosphate administration induced calcium deposition in MMP-2(+/+) aorta-derived cultured SMCs, and this calcium deposition was significantly suppressed in MMP-2(-/-) aorta-derived cultured SMCs.	beta-glycerophosphoric acid	0-21	matrix metallopeptidase 2	Mus musculus	67-72
22457042-0	2013	In vivo chondrocyte and transforming growth factor-beta1 delivery using the thermosensitive chitosan/starch/beta-glycerol phosphate hydrogel.	beta-glycerophosphoric acid	108-131	transforming growth factor, beta 1	Rattus norvegicus	24-56
22457042-1	2013	In present study, the chitosan/starch/beta-glycerol phosphate hydrogel was investigated as an effective carrier for chondrocytes and delivery of transforming growth factor-beta1.	beta-glycerophosphoric acid	38-61	transforming growth factor, beta 1	Rattus norvegicus	145-177
22457042-4	2013	Our collective results showed the potential of chitosan/starch/beta-glycerol phosphate hydrogel for effective delivery of chondrocytes and transforming growth factor-beta1, and preserve chondrocytes" phenotype and functions in vitro.	beta-glycerophosphoric acid	63-86	transforming growth factor, beta 1	Rattus norvegicus	139-171
23977325-4	2013	Inorganic phosphate, glycerol-1-phosphate and glycerol-2-phosphate at physiologically relevant concentrations (5-15 mM) significantly destabilized complexes formed by 14-3-3zeta and phosphorylated HspB6 (pHspB6), presumably, via direct interaction with the substrate-binding site of 14-3-3.	beta-glycerophosphoric acid	46-66	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	Homo sapiens	167-177
23977325-4	2013	Inorganic phosphate, glycerol-1-phosphate and glycerol-2-phosphate at physiologically relevant concentrations (5-15 mM) significantly destabilized complexes formed by 14-3-3zeta and phosphorylated HspB6 (pHspB6), presumably, via direct interaction with the substrate-binding site of 14-3-3.	beta-glycerophosphoric acid	46-66	heat shock protein family B (small) member 6	Homo sapiens	197-202
23312504-8	2013	Beta-glycerophosphate administration induced calcium deposition in MMP-2(+/+) aorta-derived cultured SMCs, and this calcium deposition was significantly suppressed in MMP-2(-/-) aorta-derived cultured SMCs.	beta-glycerophosphoric acid	0-21	matrix metallopeptidase 2	Mus musculus	167-172
23328739-8	2013	beta-Glycerophosphate stimulated calcification of HAoSMCs, which was associated with increased BALP isoforms B/I, B1x and B2.	beta-glycerophosphoric acid	0-21	immunoglobulin kappa variable 5-2	Homo sapiens	109-124
22282470-3	2012	Alkaline phosphatase (ALP) activity and mineralization induced by the presence of beta-glycerophosphate and ascorbic acid were enhanced in POB from aly/aly compared with wild-type (WT) mice.	beta-glycerophosphoric acid	82-103	mitogen-activated protein kinase kinase kinase 14	Mus musculus	148-151
23013274-4	2012	UgpB was demonstrated to bind G3P and glycerophosphocholine with dissociation constants of 0.68 +- 0.02 muM and 5.1 +- 0.3 muM, respectively, while glycerol-2-phosphate (G2P) is not a substrate.	beta-glycerophosphoric acid	148-168	glycerol-3-phosphate-binding periplasmic protein precursor	Escherichia coli	0-4
23013274-4	2012	UgpB was demonstrated to bind G3P and glycerophosphocholine with dissociation constants of 0.68 +- 0.02 muM and 5.1 +- 0.3 muM, respectively, while glycerol-2-phosphate (G2P) is not a substrate.	beta-glycerophosphoric acid	170-173	glycerol-3-phosphate-binding periplasmic protein precursor	Escherichia coli	0-4
23063979-0	2012	Interleukin-24 attenuates beta-glycerophosphate-induced calcification of vascular smooth muscle cells by inhibiting apoptosis, the expression of calcification and osteoblastic markers, and the Wnt/beta-catenin pathway.	beta-glycerophosphoric acid	26-47	interleukin 24	Homo sapiens	0-14
23063979-0	2012	Interleukin-24 attenuates beta-glycerophosphate-induced calcification of vascular smooth muscle cells by inhibiting apoptosis, the expression of calcification and osteoblastic markers, and the Wnt/beta-catenin pathway.	beta-glycerophosphoric acid	26-47	catenin beta 1	Homo sapiens	197-209
23063979-5	2012	IL-24 was applied to a beta-glycerophosphate (beta-GP)-induced rat vascular smooth muscle cell (VSMC) calcification model.	beta-glycerophosphoric acid	23-44	interleukin 24	Rattus norvegicus	0-5
23063979-5	2012	IL-24 was applied to a beta-glycerophosphate (beta-GP)-induced rat vascular smooth muscle cell (VSMC) calcification model.	beta-glycerophosphoric acid	46-53	interleukin 24	Rattus norvegicus	0-5
23063979-10	2012	Our results suggest that IL-24 inhibits beta-GP-induced VSMC calcification by inhibiting apoptosis, the expression of calcification and osteoblastic markers, and the Wnt/ beta-catenin pathway.	beta-glycerophosphoric acid	40-47	interleukin 24	Homo sapiens	25-30
23063979-10	2012	Our results suggest that IL-24 inhibits beta-GP-induced VSMC calcification by inhibiting apoptosis, the expression of calcification and osteoblastic markers, and the Wnt/ beta-catenin pathway.	beta-glycerophosphoric acid	40-47	catenin beta 1	Homo sapiens	171-183
22871591-4	2012	METHODS AND RESULTS: We found that miR-204 was suppressed in mouse aortic VSMCs during beta-glycerophosphate-induced calcification, whereas Runx2 protein levels were elevated.	beta-glycerophosphoric acid	87-108	microRNA 204	Mus musculus	35-42
22871591-5	2012	Overexpression of miR-204 by transfection of miR-204 mimics decreased Runx2 protein levels and alleviated beta-glycerophosphate-induced osteoblastic differentiation of VSMCs, whereas miR-204 inhibition by transfection of miR-204 inhibitors significantly elevated Runx2 protein levels and enhanced osteoblastic differentiation of VSMCs, suggesting the role of miR-204 as an endogenous attenuator of Runx2 in VSMC calcification.	beta-glycerophosphoric acid	106-127	microRNA 204	Mus musculus	18-25
22871591-5	2012	Overexpression of miR-204 by transfection of miR-204 mimics decreased Runx2 protein levels and alleviated beta-glycerophosphate-induced osteoblastic differentiation of VSMCs, whereas miR-204 inhibition by transfection of miR-204 inhibitors significantly elevated Runx2 protein levels and enhanced osteoblastic differentiation of VSMCs, suggesting the role of miR-204 as an endogenous attenuator of Runx2 in VSMC calcification.	beta-glycerophosphoric acid	106-127	microRNA 204	Mus musculus	45-52
22871591-5	2012	Overexpression of miR-204 by transfection of miR-204 mimics decreased Runx2 protein levels and alleviated beta-glycerophosphate-induced osteoblastic differentiation of VSMCs, whereas miR-204 inhibition by transfection of miR-204 inhibitors significantly elevated Runx2 protein levels and enhanced osteoblastic differentiation of VSMCs, suggesting the role of miR-204 as an endogenous attenuator of Runx2 in VSMC calcification.	beta-glycerophosphoric acid	106-127	microRNA 204	Mus musculus	45-52
22871591-5	2012	Overexpression of miR-204 by transfection of miR-204 mimics decreased Runx2 protein levels and alleviated beta-glycerophosphate-induced osteoblastic differentiation of VSMCs, whereas miR-204 inhibition by transfection of miR-204 inhibitors significantly elevated Runx2 protein levels and enhanced osteoblastic differentiation of VSMCs, suggesting the role of miR-204 as an endogenous attenuator of Runx2 in VSMC calcification.	beta-glycerophosphoric acid	106-127	microRNA 204	Mus musculus	45-52
22871591-5	2012	Overexpression of miR-204 by transfection of miR-204 mimics decreased Runx2 protein levels and alleviated beta-glycerophosphate-induced osteoblastic differentiation of VSMCs, whereas miR-204 inhibition by transfection of miR-204 inhibitors significantly elevated Runx2 protein levels and enhanced osteoblastic differentiation of VSMCs, suggesting the role of miR-204 as an endogenous attenuator of Runx2 in VSMC calcification.	beta-glycerophosphoric acid	106-127	microRNA 204	Mus musculus	45-52
22871591-8	2012	CONCLUSION: Our study has shown that down-regulation of miR-204 may contribute to beta-glycerophosphate-induced VSMC calcification through regulating Runx2.	beta-glycerophosphoric acid	82-103	microRNA 204	Mus musculus	56-63
22871591-8	2012	CONCLUSION: Our study has shown that down-regulation of miR-204 may contribute to beta-glycerophosphate-induced VSMC calcification through regulating Runx2.	beta-glycerophosphoric acid	82-103	runt related transcription factor 2	Mus musculus	150-155
21035140-0	2012	The effects of dexamethasone, ascorbic acid, and beta-glycerophosphate on osteoblastic differentiation by regulating estrogen receptor and osteopontin expression.	beta-glycerophosphoric acid	49-70	secreted phosphoprotein 1	Homo sapiens	139-150
21553650-0	2011	Beta-glycerophosphate accelerates RANKL-induced osteoclast formation in the presence of ascorbic acid.	beta-glycerophosphoric acid	0-21	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	34-39
22244632-11	2012	Pulp slices cultured with beta-glycerophosphate showed mineralization with up-regulation of ALP and down-regulation of fibrillin-1.	beta-glycerophosphoric acid	26-47	alkaline phosphatase, placental	Homo sapiens	92-95
22244632-11	2012	Pulp slices cultured with beta-glycerophosphate showed mineralization with up-regulation of ALP and down-regulation of fibrillin-1.	beta-glycerophosphoric acid	26-47	fibrillin 1	Homo sapiens	119-130
22244632-12	2012	CONCLUSIONS: Degradation and down-regulation of fibrillin-1 expression took place during the mineralized tissue barrier formation in exposed pulps in vivo and beta-glycerophosphate-induced pulpal mineralization in vitro.	beta-glycerophosphoric acid	159-180	fibrillin 1	Homo sapiens	48-59
21893365-6	2011	Stimulation of B7-H3 with 4H7 antibody considerably increases the numbers of osteoblasts generated from the hMSCs in the presence of inducing medium containing dexamethasone, sodium beta-glycerophosphate and l-ascorbic acid.	beta-glycerophosphoric acid	175-203	CD276 molecule	Homo sapiens	15-20
21419220-6	2011	Mandibuloacral dysplasia type A osteoblasts showed nuclear abnormalities typical of laminopathic cells, but they proliferated in culture and underwent differentiation upon stimulation with dexamethasone and beta-glycerophosphate.	beta-glycerophosphoric acid	207-228	lamin A/C	Homo sapiens	0-31
21454560-5	2011	IGF-I (25 ng/ml) significantly protected VSMCs from beta-glycerophosphate-induced osteogenic differentiation (p < 0.005) and mineral deposition (p < 0.01).	beta-glycerophosphoric acid	52-73	insulin like growth factor 1	Homo sapiens	0-5
21454560-8	2011	Inhibitors of N-linked glycosylation (tunicamycin, deoxymannojirimycin, and deoxynojirimycin) also markedly attenuated the inhibitory effect of IGF-I on beta-glycerophosphate-induced mineralization (p < 0.05) and activation of Akt and MAPK.	beta-glycerophosphoric acid	153-174	insulin like growth factor 1	Homo sapiens	144-149
21454560-8	2011	Inhibitors of N-linked glycosylation (tunicamycin, deoxymannojirimycin, and deoxynojirimycin) also markedly attenuated the inhibitory effect of IGF-I on beta-glycerophosphate-induced mineralization (p < 0.05) and activation of Akt and MAPK.	beta-glycerophosphoric acid	153-174	AKT serine/threonine kinase 1	Homo sapiens	230-233
21553650-6	2011	In addition, beta-glycerophosphate and ascorbic acid together enhanced the induction of COX-2 following RANKL stimulation.	beta-glycerophosphoric acid	13-34	cytochrome c oxidase II, mitochondrial	Mus musculus	88-93
21553650-3	2011	Beta-Glycerophosphate dose-dependently increased RANKL-induced osteoclast formation in the presence of ascorbic acid.	beta-glycerophosphoric acid	0-21	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	49-54
21553650-6	2011	In addition, beta-glycerophosphate and ascorbic acid together enhanced the induction of COX-2 following RANKL stimulation.	beta-glycerophosphoric acid	13-34	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	104-109
21553650-7	2011	Taken together, our data suggest that beta-glycerophosphate and ascorbic acid have synergistic effects on osteoclast formation, increasing RANKL-mediated induction of c-Fos, NFATc1 and COX-2 in osteoclast precursors.	beta-glycerophosphoric acid	38-59	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	139-144
21553650-7	2011	Taken together, our data suggest that beta-glycerophosphate and ascorbic acid have synergistic effects on osteoclast formation, increasing RANKL-mediated induction of c-Fos, NFATc1 and COX-2 in osteoclast precursors.	beta-glycerophosphoric acid	38-59	FBJ osteosarcoma oncogene	Mus musculus	167-172
21553650-7	2011	Taken together, our data suggest that beta-glycerophosphate and ascorbic acid have synergistic effects on osteoclast formation, increasing RANKL-mediated induction of c-Fos, NFATc1 and COX-2 in osteoclast precursors.	beta-glycerophosphoric acid	38-59	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1	Mus musculus	174-180
21553650-7	2011	Taken together, our data suggest that beta-glycerophosphate and ascorbic acid have synergistic effects on osteoclast formation, increasing RANKL-mediated induction of c-Fos, NFATc1 and COX-2 in osteoclast precursors.	beta-glycerophosphoric acid	38-59	cytochrome c oxidase II, mitochondrial	Mus musculus	185-190
21553650-5	2011	While the combination of beta-glycerophosphate and ascorbic acid inhibited RANKL-stimulated activation of ERK and p38, and degradation of IkappaB, it increased the induction of c-Fos and NFATc1.	beta-glycerophosphoric acid	25-46	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	75-80
21553650-5	2011	While the combination of beta-glycerophosphate and ascorbic acid inhibited RANKL-stimulated activation of ERK and p38, and degradation of IkappaB, it increased the induction of c-Fos and NFATc1.	beta-glycerophosphoric acid	25-46	mitogen-activated protein kinase 14	Mus musculus	114-117
21553650-5	2011	While the combination of beta-glycerophosphate and ascorbic acid inhibited RANKL-stimulated activation of ERK and p38, and degradation of IkappaB, it increased the induction of c-Fos and NFATc1.	beta-glycerophosphoric acid	25-46	FBJ osteosarcoma oncogene	Mus musculus	177-182
21553650-5	2011	While the combination of beta-glycerophosphate and ascorbic acid inhibited RANKL-stimulated activation of ERK and p38, and degradation of IkappaB, it increased the induction of c-Fos and NFATc1.	beta-glycerophosphoric acid	25-46	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1	Mus musculus	187-193
21268079-7	2011	Furthermore, oxLDL"s ability to enhance both beta-glycerophosphate-induced Osx expression and alkaline phosphatase activity was prevented when the BASMCs were first transfected with Msx2-specific siRNA.	beta-glycerophosphoric acid	45-66	msh homeobox 2	Bos taurus	182-186
20033237-4	2010	We herein showed that taurine partially restored Axl and Gas6 expression in beta-glycerophosphate (beta-GP)-induced VSMC calcification model.	beta-glycerophosphoric acid	76-97	AXL receptor tyrosine kinase	Homo sapiens	49-52
21268079-3	2011	Thus, by culturing BASMCs in the absence or presence of beta-glycerophosphate and/or oxLDL, we demonstrate that beta-glycerophosphate induces both Runx2 and Osterix (Osx) expression.	beta-glycerophosphoric acid	112-133	RUNX family transcription factor 2	Bos taurus	147-152
21268079-6	2011	Similar to its effect on Osx expression, oxLDL was found to synergistically enhance beta-glycerophosphate-induced Msx2 expression in an extracellular signal-regulated kinase 1 and 2 (Erk 1 and 2)-dependent manner.	beta-glycerophosphoric acid	84-105	msh homeobox 2	Bos taurus	114-118
21268079-6	2011	Similar to its effect on Osx expression, oxLDL was found to synergistically enhance beta-glycerophosphate-induced Msx2 expression in an extracellular signal-regulated kinase 1 and 2 (Erk 1 and 2)-dependent manner.	beta-glycerophosphoric acid	84-105	mitogen-activated protein kinase 3	Bos taurus	136-181
21268079-6	2011	Similar to its effect on Osx expression, oxLDL was found to synergistically enhance beta-glycerophosphate-induced Msx2 expression in an extracellular signal-regulated kinase 1 and 2 (Erk 1 and 2)-dependent manner.	beta-glycerophosphoric acid	84-105	mitogen-activated protein kinase 3	Bos taurus	183-194
20647695-10	2010	High beta-glycerophosphate increased expression levels of osteopontin and osteocalcin as well as calcium staining in HASMCs, but these changes were attenuated by treatment with BMP-7.	beta-glycerophosphoric acid	5-26	secreted phosphoprotein 1	Mus musculus	58-69
20647695-10	2010	High beta-glycerophosphate increased expression levels of osteopontin and osteocalcin as well as calcium staining in HASMCs, but these changes were attenuated by treatment with BMP-7.	beta-glycerophosphoric acid	5-26	bone gamma-carboxyglutamate protein 2	Mus musculus	74-85
20647695-10	2010	High beta-glycerophosphate increased expression levels of osteopontin and osteocalcin as well as calcium staining in HASMCs, but these changes were attenuated by treatment with BMP-7.	beta-glycerophosphoric acid	5-26	bone morphogenetic protein 7	Mus musculus	177-182
20033237-7	2010	These results demonstrate for the first time that taurine stimulates expression of Axl and Gas6 via TAUT/ERK signaling pathway in beta-GP-induced VSMC calcification model.	beta-glycerophosphoric acid	130-137	AXL receptor tyrosine kinase	Homo sapiens	83-86
20033237-7	2010	These results demonstrate for the first time that taurine stimulates expression of Axl and Gas6 via TAUT/ERK signaling pathway in beta-GP-induced VSMC calcification model.	beta-glycerophosphoric acid	130-137	growth arrest specific 6	Homo sapiens	91-95
20033237-4	2010	We herein showed that taurine partially restored Axl and Gas6 expression in beta-glycerophosphate (beta-GP)-induced VSMC calcification model.	beta-glycerophosphoric acid	76-97	growth arrest specific 6	Homo sapiens	57-61
20033237-7	2010	These results demonstrate for the first time that taurine stimulates expression of Axl and Gas6 via TAUT/ERK signaling pathway in beta-GP-induced VSMC calcification model.	beta-glycerophosphoric acid	130-137	solute carrier family 6 member 6	Homo sapiens	100-104
20033237-4	2010	We herein showed that taurine partially restored Axl and Gas6 expression in beta-glycerophosphate (beta-GP)-induced VSMC calcification model.	beta-glycerophosphoric acid	99-106	AXL receptor tyrosine kinase	Homo sapiens	49-52
20033237-7	2010	These results demonstrate for the first time that taurine stimulates expression of Axl and Gas6 via TAUT/ERK signaling pathway in beta-GP-induced VSMC calcification model.	beta-glycerophosphoric acid	130-137	mitogen-activated protein kinase 1	Homo sapiens	105-108
20033237-4	2010	We herein showed that taurine partially restored Axl and Gas6 expression in beta-glycerophosphate (beta-GP)-induced VSMC calcification model.	beta-glycerophosphoric acid	99-106	growth arrest specific 6	Homo sapiens	57-61
20464482-7	2010	SMF in combination with Dex/beta-GP significantly increased the mRNA expression of osteogenic genes, as well as the ALP activity and extracellular calcium concentration at the early stage, followed by obvious calcium deposits later.	beta-glycerophosphoric acid	28-35	PDZ and LIM domain 3	Rattus norvegicus	116-119
19837997-3	2009	Histochemistry revealed morphologically distinct, chondrocyte-like cells, surrounded by a sulfated proteoglycan-rich extracellular matrix in the group treated with bone morphogenetic protein 2 (BMP-2), while cells cultured with dexamethasone, ascorbate-2-phosphate, and beta-glycerophosphate displayed a spindle-shaped morphology and deposited a mineralized matrix.	beta-glycerophosphoric acid	270-291	bone morphogenetic protein 2	Homo sapiens	164-192
19782780-5	2010	METHODS: Expression of endogenous Ang-1 and its binding receptor Tie 2 mRNA was examined in osteoblast-like cells and primary mouse calvarial cells by RT-PCR analysis, and was also monitored during osteoblast differentiation induced by BMP-2 and/or ascorbic acid and beta-glycerophosphate.	beta-glycerophosphoric acid	267-288	angiopoietin 1	Mus musculus	34-39
19782780-5	2010	METHODS: Expression of endogenous Ang-1 and its binding receptor Tie 2 mRNA was examined in osteoblast-like cells and primary mouse calvarial cells by RT-PCR analysis, and was also monitored during osteoblast differentiation induced by BMP-2 and/or ascorbic acid and beta-glycerophosphate.	beta-glycerophosphoric acid	267-288	TEK receptor tyrosine kinase	Mus musculus	65-70
18683233-7	2009	In the case of supplementing Dex and beta-GP to the medium, the level of ALP activity in MSCs cultured on SPV-H was higher than that on PV-H at all time points during the 21-day culture.	beta-glycerophosphoric acid	37-44	alkaline phosphatase, placental	Homo sapiens	73-76
18461557-8	2008	In contrast, oxLDL did not affect either Smad 1/5/8 activation or Runx2 activation but rather, it enhanced both beta-glycerophosphate-induced Osx expression and osteoblast differentiation in an extracellular signal-regulated kinase 1 and 2 (Erk 1 and 2) -dependent manner.	beta-glycerophosphoric acid	112-133	mitogen-activated protein kinase 3	Bos taurus	194-239
19505182-13	2009	When pellets were switched to culture medium containing beta-glycerophosphate, independent of the presence or absence of transforming growth factor beta (TGF-beta), mineralization was observed with a concomitant reduction in VEGF and matrix metalloproteinase (MMP) release.	beta-glycerophosphoric acid	56-77	vascular endothelial growth factor A	Homo sapiens	225-229
19051077-7	2008	beta-glycerophosphate-induced oxidative stress was associated with Cbfa-1 expression followed by ALP expression and activity, meanwhile the VSMCs expressing ALP diffusely calcified their extracellular matrix.	beta-glycerophosphoric acid	0-21	RUNX family transcription factor 2	Rattus norvegicus	67-73
18683233-5	2009	The culture tests using MSCs show that the level of alkaline phosphatase (ALP) activity in the cells cultured on SPV-H increased during the 21-day culture in a medium without Dex and beta-GP.	beta-glycerophosphoric acid	183-190	alkaline phosphatase, placental	Homo sapiens	52-72
18683233-5	2009	The culture tests using MSCs show that the level of alkaline phosphatase (ALP) activity in the cells cultured on SPV-H increased during the 21-day culture in a medium without Dex and beta-GP.	beta-glycerophosphoric acid	183-190	alkaline phosphatase, placental	Homo sapiens	74-77
19949969-6	2009	Stimulation of MSCs for 28 days with ascorbate/beta-glycerophosphate (asc/bGp) induced UCN gene expression at day 14.	beta-glycerophosphoric acid	47-68	bone gamma-carboxyglutamate protein	Homo sapiens	74-77
19949969-6	2009	Stimulation of MSCs for 28 days with ascorbate/beta-glycerophosphate (asc/bGp) induced UCN gene expression at day 14.	beta-glycerophosphoric acid	47-68	urocortin	Homo sapiens	87-90
19254785-5	2009	Treatment of C3H10T1/2 cells with WIF-1 significantly reduced alkaline phosphatase (ALP) activities induced by either osteogenic medium (OM, ascorbic acid and beta-glycerophosphate) or Wnt-3a conditioned medium (CM) in a dose-dependent manner.	beta-glycerophosphoric acid	159-180	Wnt inhibitory factor 1	Mus musculus	34-39
18461557-7	2008	Surprisingly, beta-glycerophosphate alone was found to enhance Osterix (Osx) expression by inducing both Smad 1/5/8 activation and Runx2 expression.	beta-glycerophosphoric acid	14-35	SMAD family member 1	Bos taurus	105-113
18461557-8	2008	In contrast, oxLDL did not affect either Smad 1/5/8 activation or Runx2 activation but rather, it enhanced both beta-glycerophosphate-induced Osx expression and osteoblast differentiation in an extracellular signal-regulated kinase 1 and 2 (Erk 1 and 2) -dependent manner.	beta-glycerophosphoric acid	112-133	mitogen-activated protein kinase 3	Bos taurus	241-252
18461557-7	2008	Surprisingly, beta-glycerophosphate alone was found to enhance Osterix (Osx) expression by inducing both Smad 1/5/8 activation and Runx2 expression.	beta-glycerophosphoric acid	14-35	RUNX family transcription factor 2	Bos taurus	131-136
18060526-5	2008	The results showed that taurine inhibited the beta-glycerophosphate-induced osteoblastic differentiation of VSMCs as evidenced by both the decreasing alkaline phosphate (ALP) activity and expression of the core binding factor alpha1 (Cbfalpha1).	beta-glycerophosphoric acid	46-67	RUNX family transcription factor 2	Homo sapiens	206-232
18500657-4	2008	Levamisole inhibited beta-glycerophosphate-induced mineralization, TNAP and PHEX expression, and the increase in enzymatic activity of NPP1 (5"-nucleotide pyrophosphatase phosphodiesterase 1), but did not inhibit NaH(2)PO(4)-induced mineralization.	beta-glycerophosphoric acid	21-42	phosphate regulating endopeptidase homolog X-linked	Homo sapiens	76-80
18060526-5	2008	The results showed that taurine inhibited the beta-glycerophosphate-induced osteoblastic differentiation of VSMCs as evidenced by both the decreasing alkaline phosphate (ALP) activity and expression of the core binding factor alpha1 (Cbfalpha1).	beta-glycerophosphoric acid	46-67	RUNX family transcription factor 2	Homo sapiens	234-243
17583554-5	2008	hMSCs, induced to differentiate with osteogenic medium (OGM) containing ascorbate, beta-glycerophosphate (beta-GP), and dexamethasone (DEX), showed an increase in mRNA and protein secretion of the ELR(+) CXC chemokines CXCL8 and CXCL1.	beta-glycerophosphoric acid	106-113	C-X-C motif chemokine ligand 8	Homo sapiens	219-224
18166153-4	2008	Retroviral transduction of the sFRP-2 but not other sFRPs also significantly enhanced ALP activity induced by beta-glycerophosphate and ascorbic acid.	beta-glycerophosphoric acid	110-131	secreted frizzled-related protein 2	Mus musculus	31-37
18547474-4	2008	Also when the cells were further cultured in osteogenic medium (containing beta-glycerophosphate, ascorbic acid and dexamethasone) for 40 days, MEPE down-regulation coupled to an increased expression of osteogenic markers, such as osteocalcin and alkaline phosphatase, occurred earlier in PaMCs than in DPMCs.	beta-glycerophosphoric acid	75-96	matrix extracellular phosphoglycoprotein	Homo sapiens	144-148
18547474-4	2008	Also when the cells were further cultured in osteogenic medium (containing beta-glycerophosphate, ascorbic acid and dexamethasone) for 40 days, MEPE down-regulation coupled to an increased expression of osteogenic markers, such as osteocalcin and alkaline phosphatase, occurred earlier in PaMCs than in DPMCs.	beta-glycerophosphoric acid	75-96	bone gamma-carboxyglutamate protein	Homo sapiens	231-242
17583554-5	2008	hMSCs, induced to differentiate with osteogenic medium (OGM) containing ascorbate, beta-glycerophosphate (beta-GP), and dexamethasone (DEX), showed an increase in mRNA and protein secretion of the ELR(+) CXC chemokines CXCL8 and CXCL1.	beta-glycerophosphoric acid	106-113	C-X-C motif chemokine ligand 1	Homo sapiens	229-234
17350357-9	2007	During matrix mineralization induced by beta-glycerophosphate (beta GP), FGF23 expression was transiently upregulated and then decreased to levels lower than in their non-beta GP-treated counterparts.	beta-glycerophosphoric acid	40-61	fibroblast growth factor 23	Rattus norvegicus	73-78
18413270-10	2008	Mineralization induced by beta-GP and Pi decreased TNAP activity in the osteoblast but not in cartilage organoid culture.	beta-glycerophosphoric acid	26-33	alkaline phosphatase, liver/bone/kidney	Mus musculus	51-55
18197755-14	2008	Our data suggest a role for miR-26a in the differentiation induced by treatment with dexamethasone, ascorbic acid, and beta-glycerol phosphate of hADSCs toward the osteogenic lineage by targeting its predicted target, the SMAD1 protein.	beta-glycerophosphoric acid	119-142	microRNA 26a-1	Homo sapiens	28-35
18197755-14	2008	Our data suggest a role for miR-26a in the differentiation induced by treatment with dexamethasone, ascorbic acid, and beta-glycerol phosphate of hADSCs toward the osteogenic lineage by targeting its predicted target, the SMAD1 protein.	beta-glycerophosphoric acid	119-142	SMAD family member 1	Homo sapiens	222-227
17881279-10	2008	Half of Abl resolved with Triton X-100 was demonstrated to have catalytic activity as shown with positive phosphotyrosine staining on the Western blot and competitive elution with a specific phosphate, such as sodium beta-glycerophosphate, from HiTrap-PEP(Taxol), but this was not associated with RACK1.	beta-glycerophosphoric acid	210-238	c-abl oncogene 1, non-receptor tyrosine kinase	Mus musculus	8-11
17881279-10	2008	Half of Abl resolved with Triton X-100 was demonstrated to have catalytic activity as shown with positive phosphotyrosine staining on the Western blot and competitive elution with a specific phosphate, such as sodium beta-glycerophosphate, from HiTrap-PEP(Taxol), but this was not associated with RACK1.	beta-glycerophosphoric acid	210-238	receptor for activated C kinase 1	Mus musculus	297-302
18458444-4	2007	When human mesenchymal stem cells (hMSCs) were cultured on a HAP ceramic in a differentiation medium supplemented with dexamethasone, beta-glycerophosphate and ascorbic acid, hMSCs spread well within 1 h. The alkaline phosphatase (ALP) activity of hMSCs cultured on the Fn-calcium phosphate composite layer significantly increased compared with that of hMSCs cultured on the untreated HAP ceramic.	beta-glycerophosphoric acid	134-155	alkaline phosphatase, placental	Homo sapiens	209-229
16795048-3	2006	VSMCs cultured in plates with FN (0-20 microg/cm2) coating were induced to calcify by 10 mM sodium beta-glycerophosphate (beta-GP).	beta-glycerophosphoric acid	92-120	fibronectin 1	Homo sapiens	30-32
17255529-8	2007	In contrast, Axl-mediated signaling is not enhanced by overexpression of kinase-dead Axl and mineralization is accelerated, although beta-glycerophosphate is still required for this effect.	beta-glycerophosphoric acid	133-154	AXL receptor tyrosine kinase	Homo sapiens	13-16
16956801-7	2007	However, cells expressing LRP5DeltaN-V showed increased alkaline phosphatase activity and bone nodule formation compared to cells transfected with empty vector or LRP5DeltaN-A after osteogenic supplement (OS: beta-glycerophosphate and l-ascorbic acid) treatment.	beta-glycerophosphoric acid	209-230	LDL receptor related protein 5	Homo sapiens	26-36
17917883-6	2007	The treatment induced extracellular calcium deposition and gene and protein expression of osteonectin (ON) and bone sialoprotein (BSP): beta-GlyP induced an increase (c. 2.2-fold) of the ON gene and dexa augmented (c. 2.7-fold) the gene expression of BSP II.	beta-glycerophosphoric acid	136-145	integrin binding sialoprotein	Homo sapiens	111-128
17917883-6	2007	The treatment induced extracellular calcium deposition and gene and protein expression of osteonectin (ON) and bone sialoprotein (BSP): beta-GlyP induced an increase (c. 2.2-fold) of the ON gene and dexa augmented (c. 2.7-fold) the gene expression of BSP II.	beta-glycerophosphoric acid	136-145	integrin binding sialoprotein	Homo sapiens	130-133
17917883-6	2007	The treatment induced extracellular calcium deposition and gene and protein expression of osteonectin (ON) and bone sialoprotein (BSP): beta-GlyP induced an increase (c. 2.2-fold) of the ON gene and dexa augmented (c. 2.7-fold) the gene expression of BSP II.	beta-glycerophosphoric acid	136-145	integrin binding sialoprotein	Homo sapiens	251-257
17882698-3	2007	Cultured human cells showed relatively low alkaline phosphatase (ALP) activity in the presence of dexamethasone (Dex) and beta-glycerophosphate (beta-Gly).	beta-glycerophosphoric acid	122-143	alkaline phosphatase, placental	Homo sapiens	65-68
17882698-3	2007	Cultured human cells showed relatively low alkaline phosphatase (ALP) activity in the presence of dexamethasone (Dex) and beta-glycerophosphate (beta-Gly).	beta-glycerophosphoric acid	145-153	alkaline phosphatase, placental	Homo sapiens	43-63
17882698-3	2007	Cultured human cells showed relatively low alkaline phosphatase (ALP) activity in the presence of dexamethasone (Dex) and beta-glycerophosphate (beta-Gly).	beta-glycerophosphoric acid	145-153	alkaline phosphatase, placental	Homo sapiens	65-68
17882698-5	2007	In porcine cells, beta-Gly alone or a combination of Dex and beta-Gly significantly increased ALP activity; however, addition of VitD3 reduced this activity.	beta-glycerophosphoric acid	18-26	alkaline phosphatase, placental	Homo sapiens	94-97
17882698-5	2007	In porcine cells, beta-Gly alone or a combination of Dex and beta-Gly significantly increased ALP activity; however, addition of VitD3 reduced this activity.	beta-glycerophosphoric acid	61-69	alkaline phosphatase, placental	Homo sapiens	94-97
16795048-3	2006	VSMCs cultured in plates with FN (0-20 microg/cm2) coating were induced to calcify by 10 mM sodium beta-glycerophosphate (beta-GP).	beta-glycerophosphoric acid	122-129	fibronectin 1	Homo sapiens	30-32
16817793-1	2006	beta-glycerophosphate, a phosphate donor, and uremic sera induce osteopontin (OPN) expression in bovine vascular smooth muscle cells (VSMCs).	beta-glycerophosphoric acid	0-21	secreted phosphoprotein 1	Homo sapiens	65-76
16817793-1	2006	beta-glycerophosphate, a phosphate donor, and uremic sera induce osteopontin (OPN) expression in bovine vascular smooth muscle cells (VSMCs).	beta-glycerophosphoric acid	0-21	secreted phosphoprotein 1	Homo sapiens	78-81
16516858-3	2006	When the cells were further cultured in the presence of beta-glycerophosphate, ascorbic acid, and dexamethasone for 14 days, mineralized areas together with osteogenic differentiation evidenced by high alkaline phosphatase activity and osteocalcin contents were observed.	beta-glycerophosphoric acid	56-77	bone gamma-carboxyglutamate protein	Homo sapiens	236-247
16862747-3	2006	We found that when beta-glycerophosphate was added to the culture medium, the mRNA of the dentin sialophosphoprotein (DSPP) gene coding dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) was expressed, and an increase in alkaline phosphatase, an early marker of odontoblast differentiation, was also demonstrated.	beta-glycerophosphoric acid	19-40	dentin sialophosphoprotein	Rattus norvegicus	90-116
16862747-3	2006	We found that when beta-glycerophosphate was added to the culture medium, the mRNA of the dentin sialophosphoprotein (DSPP) gene coding dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) was expressed, and an increase in alkaline phosphatase, an early marker of odontoblast differentiation, was also demonstrated.	beta-glycerophosphoric acid	19-40	dentin sialophosphoprotein	Rattus norvegicus	118-122
16862747-3	2006	We found that when beta-glycerophosphate was added to the culture medium, the mRNA of the dentin sialophosphoprotein (DSPP) gene coding dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) was expressed, and an increase in alkaline phosphatase, an early marker of odontoblast differentiation, was also demonstrated.	beta-glycerophosphoric acid	19-40	dentin sialophosphoprotein	Rattus norvegicus	136-155
16862747-3	2006	We found that when beta-glycerophosphate was added to the culture medium, the mRNA of the dentin sialophosphoprotein (DSPP) gene coding dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) was expressed, and an increase in alkaline phosphatase, an early marker of odontoblast differentiation, was also demonstrated.	beta-glycerophosphoric acid	19-40	dentin sialophosphoprotein	Rattus norvegicus	118-121
16494847-5	2006	Our results indicate that beta-glycerophosphate treatment of OLC cultures decreases Lhx6 transcript levels in vitro.	beta-glycerophosphoric acid	26-47	LIM homeobox protein 6	Mus musculus	84-88
16317517-5	2006	In SaOS-2 cells, TNSALP mRNA measured by real-time RT-PCR reached a peak level at 72 h after the addition of beta-glycerophosphate.	beta-glycerophosphoric acid	109-130	alkaline phosphatase, biomineralization associated	Homo sapiens	17-23
16317517-7	2006	These results suggest that TNSALP, PHEX and MEPE were concordantly induced by beta-glycerophosphate on mineralisation.	beta-glycerophosphoric acid	78-99	matrix extracellular phosphoglycoprotein	Homo sapiens	44-48
16526573-3	2006	We found that when beta-glycerophosphate was added to the culture medium, dentin sialophosphoprotein mRNA coding dentin sialoprotein (DSP) was expressed.	beta-glycerophosphoric acid	19-40	dentin sialophosphoprotein	Homo sapiens	113-132
16526573-3	2006	We found that when beta-glycerophosphate was added to the culture medium, dentin sialophosphoprotein mRNA coding dentin sialoprotein (DSP) was expressed.	beta-glycerophosphoric acid	19-40	dentin sialophosphoprotein	Homo sapiens	134-137
16317517-6	2006	PHEX and MEPE mRNAs were also induced by beta-glycerophosphate.	beta-glycerophosphoric acid	41-62	phosphate regulating endopeptidase homolog X-linked	Homo sapiens	0-4
16317517-6	2006	PHEX and MEPE mRNAs were also induced by beta-glycerophosphate.	beta-glycerophosphoric acid	41-62	matrix extracellular phosphoglycoprotein	Homo sapiens	9-13
16317517-7	2006	These results suggest that TNSALP, PHEX and MEPE were concordantly induced by beta-glycerophosphate on mineralisation.	beta-glycerophosphoric acid	78-99	alkaline phosphatase, biomineralization associated	Homo sapiens	27-33
16317517-7	2006	These results suggest that TNSALP, PHEX and MEPE were concordantly induced by beta-glycerophosphate on mineralisation.	beta-glycerophosphoric acid	78-99	phosphate regulating endopeptidase homolog X-linked	Homo sapiens	35-39
15541395-3	2004	Fibroblast growth factor-2 (FGF-2) stimulated the proliferation of these immature cells and the subsequent production of mineralized calcium was induced by beta-glycerophosphate treatment.	beta-glycerophosphoric acid	156-177	fibroblast growth factor 2	Rattus norvegicus	0-26
15777654-4	2005	Using reversed transcribed PCR, we identified ADAMTS-1, -4 and -5 mRNA expression in cultures of rat osteoblasts treated with ascorbic acid, beta-glycerophosphate and dexamethasone, molecules known to drive osteoblast differentiation.	beta-glycerophosphoric acid	141-162	ADAM metallopeptidase with thrombospondin type 1 motif, 1	Rattus norvegicus	46-65
15625085-4	2005	Cells grown in ascorbate and beta-glycerophosphate produce alkaline phosphatase and osteocalcin and mineralize matrix.	beta-glycerophosphoric acid	29-50	bone gamma-carboxyglutamate protein 2	Mus musculus	84-95
15974530-6	2005	Cultured ICs did not calcify spontaneously, however when the growth medium was supplemented with beta-glycerophosphate (an organic phosphate) it induced the formation of calcified nodules that expressed osteonectin and ALP, but not SM alpha-actin.	beta-glycerophosphoric acid	97-118	alkaline phosphatase, placental	Homo sapiens	219-222
15974530-8	2005	ALP activity was considerably increased in beta-glycerophosphate-treated ICs, and this correlated with the calcium content (r = 0.5: p = 0.01).	beta-glycerophosphoric acid	43-64	alkaline phosphatase, placental	Homo sapiens	0-3
15974530-9	2005	Levamisol (an ALP inhibitor) inhibited the beta-glycerophosphate-induced calcification process, as well as the expression of osteoblastic differentiation markers.	beta-glycerophosphoric acid	43-64	alkaline phosphatase, placental	Homo sapiens	14-17
15541395-3	2004	Fibroblast growth factor-2 (FGF-2) stimulated the proliferation of these immature cells and the subsequent production of mineralized calcium was induced by beta-glycerophosphate treatment.	beta-glycerophosphoric acid	156-177	fibroblast growth factor 2	Rattus norvegicus	28-33
15250834-5	2004	The papilla and pulp cells showed mineralization and dentin sialophosphoprotein (DSPP) expression when cultured in the presence of beta-glycerophosphate.	beta-glycerophosphoric acid	131-152	dentin sialophosphoprotein	Homo sapiens	81-85
15542045-5	2004	FGF23 expression in the bone cells increased with increased mineralization over a 20-day treatment period under mineralizing conditions with beta-glycerophosphate, while PHEX expression decreased.	beta-glycerophosphoric acid	141-162	fibroblast growth factor 23	Homo sapiens	0-5
15268910-9	2004	However, when cultured in the presence of 5 mM beta-glycerophosphate, ascorbate, and dexamethasone for 29 days, which are similar conditions to those described by Owen in his differentiation model in rat osteoblasts, a progressive inhibition of MEPE gene expression to 20% of the maximum was observed.	beta-glycerophosphoric acid	47-68	matrix extracellular phosphoglycoprotein	Rattus norvegicus	245-249
14648194-10	2004	After 4 weeks of culture with 2 mM beta-GP and 50 microg/ml AA, HFC formed von Kossa staining-positive calcified deposits on culture dishes, and also expressed Ocn mRNA.	beta-glycerophosphoric acid	35-42	bone gamma-carboxyglutamate protein	Homo sapiens	160-163
15094391-6	2004	Moreover, SVCT2-overexpressing cells exhibited more ability to promote mineralization and increase calcium deposition under the stimulation of 5 mM beta-glycerophosphate.	beta-glycerophosphoric acid	148-169	solute carrier family 23 member 2	Homo sapiens	10-15
15086777-2	2004	Alkaline phosphatase-expressing cells were most frequently observed when the hMSCs were treated with 2.5 ng/ml of basic fibroblast growth factor (bFGF) and 50 ng/ml of bone morphogenetic protein (BMP)-2 for 4 days in culture after a 6-day incubation in osteogenic medium containing dexamethasone, ascorbic acid-2-phosphate, and beta-glycerophosphate.	beta-glycerophosphoric acid	328-349	fibroblast growth factor 2	Homo sapiens	114-144
15086777-2	2004	Alkaline phosphatase-expressing cells were most frequently observed when the hMSCs were treated with 2.5 ng/ml of basic fibroblast growth factor (bFGF) and 50 ng/ml of bone morphogenetic protein (BMP)-2 for 4 days in culture after a 6-day incubation in osteogenic medium containing dexamethasone, ascorbic acid-2-phosphate, and beta-glycerophosphate.	beta-glycerophosphoric acid	328-349	fibroblast growth factor 2	Homo sapiens	146-150
15086777-2	2004	Alkaline phosphatase-expressing cells were most frequently observed when the hMSCs were treated with 2.5 ng/ml of basic fibroblast growth factor (bFGF) and 50 ng/ml of bone morphogenetic protein (BMP)-2 for 4 days in culture after a 6-day incubation in osteogenic medium containing dexamethasone, ascorbic acid-2-phosphate, and beta-glycerophosphate.	beta-glycerophosphoric acid	328-349	bone morphogenetic protein 2	Homo sapiens	168-202
12827032-3	2003	Adrenomedullin and CNP lowered beta-glycerophosphate-induced increase in VSMC growth.	beta-glycerophosphoric acid	31-52	adrenomedullin	Rattus norvegicus	0-14
14624496-2	2003	After a 2-week culture of the BMCs in the presence of beta-glycerophosphate and dexamethasone, many macroscopic mineralized areas with high alkaline phosphatase (ALP) activity were seen on the ZnTCP/HAP ceramic disks.	beta-glycerophosphoric acid	54-75	alkaline phosphatase, placental	Homo sapiens	140-160
14624496-2	2003	After a 2-week culture of the BMCs in the presence of beta-glycerophosphate and dexamethasone, many macroscopic mineralized areas with high alkaline phosphatase (ALP) activity were seen on the ZnTCP/HAP ceramic disks.	beta-glycerophosphoric acid	54-75	alkaline phosphatase, placental	Homo sapiens	162-165
12783985-7	2003	During the chondrogenesis phase, type I collagen and bone sialoprotein were produced in the outer portion of the cartilage bead, which, upon subsequent exposure to beta-glycerophosphate, mineralized and accumulated extracellular bone sialoprotein and osteocalcin.	beta-glycerophosphoric acid	164-185	bone gamma-carboxyglutamate protein	Homo sapiens	251-262
12827032-3	2003	Adrenomedullin and CNP lowered beta-glycerophosphate-induced increase in VSMC growth.	beta-glycerophosphoric acid	31-52	natriuretic peptide C	Rattus norvegicus	19-22
12827032-9	2003	These data suggested that beta-glycerophosphate-induced calcification in VSMCs was inhibited by ADM, CNP, and PTHrP.	beta-glycerophosphoric acid	26-47	natriuretic peptide C	Rattus norvegicus	101-104
12827032-9	2003	These data suggested that beta-glycerophosphate-induced calcification in VSMCs was inhibited by ADM, CNP, and PTHrP.	beta-glycerophosphoric acid	26-47	parathyroid hormone-like hormone	Rattus norvegicus	110-115
12878983-9	2003	Our findings indicate that 15d-PGJ2-induced PPAR-gamma abrogates beta-glycerophosphate-activated Cbfa1 and NF-kappaB.	beta-glycerophosphoric acid	65-86	nuclear factor kappa B subunit 1	Homo sapiens	107-116
12371973-7	2002	RESULTS: beta-glycerophosphate increased osteopontin expression and alkaline phosphatase activity in BVSMC.	beta-glycerophosphoric acid	9-30	secreted phosphoprotein 1	Homo sapiens	41-52
12946103-6	2003	Core-binding factor A1 (cbfa1) is a transcription factor critical for osteoblast differentiation, and we show here that it is activated by the osteoblast differentiation agent, beta-glycerophosphate.	beta-glycerophosphoric acid	177-198	RUNX family transcription factor 2	Homo sapiens	0-22
12946103-6	2003	Core-binding factor A1 (cbfa1) is a transcription factor critical for osteoblast differentiation, and we show here that it is activated by the osteoblast differentiation agent, beta-glycerophosphate.	beta-glycerophosphoric acid	177-198	RUNX family transcription factor 2	Homo sapiens	24-29
12946103-8	2003	Using retardation assays, we show that TNF significantly inhibits cbfal activation by beta-glycerophosphate, manifested by reduced DNA-binding activity.	beta-glycerophosphoric acid	86-107	tumor necrosis factor	Homo sapiens	39-42
12946103-12	2003	In summary, TNF blocks expression of osteoblast differentiation markers and inhibits beta-glycerophosphate-induced activation of the osteoblast differentiation factor cbfa1.	beta-glycerophosphoric acid	85-106	tumor necrosis factor	Homo sapiens	12-15
12946103-12	2003	In summary, TNF blocks expression of osteoblast differentiation markers and inhibits beta-glycerophosphate-induced activation of the osteoblast differentiation factor cbfa1.	beta-glycerophosphoric acid	85-106	RUNX family transcription factor 2	Homo sapiens	167-172
12878983-6	2003	Further examination of downstream osteogenic signaling pathways induced by beta-glycerophosphate and ascorbic acid reveals that induction of osteoblast differentiation by these agents involves activation of the transcription factors Cbfa1 and NF-kappaB.	beta-glycerophosphoric acid	75-96	RUNX family transcription factor 2	Homo sapiens	233-238
12878983-6	2003	Further examination of downstream osteogenic signaling pathways induced by beta-glycerophosphate and ascorbic acid reveals that induction of osteoblast differentiation by these agents involves activation of the transcription factors Cbfa1 and NF-kappaB.	beta-glycerophosphoric acid	75-96	nuclear factor kappa B subunit 1	Homo sapiens	243-252
12878983-9	2003	Our findings indicate that 15d-PGJ2-induced PPAR-gamma abrogates beta-glycerophosphate-activated Cbfa1 and NF-kappaB.	beta-glycerophosphoric acid	65-86	peroxisome proliferator activated receptor gamma	Homo sapiens	44-54
12878983-9	2003	Our findings indicate that 15d-PGJ2-induced PPAR-gamma abrogates beta-glycerophosphate-activated Cbfa1 and NF-kappaB.	beta-glycerophosphoric acid	65-86	RUNX family transcription factor 2	Homo sapiens	97-102
12371973-13	2002	CONCLUSION: beta-glycerophosphate and uremic sera induce calcification and osteopontin expression in BVSMC.	beta-glycerophosphoric acid	12-33	secreted phosphoprotein 1	Homo sapiens	75-86
12114316-6	2002	THP-1 cells or PBMCs induced ALP activity and its gene expression in HVSMCs and the cells with high expression of ALP calcified their extracellular matrix by the addition of beta-glycerophosphate.	beta-glycerophosphoric acid	174-195	alkaline phosphatase, placental	Homo sapiens	29-32
12114316-6	2002	THP-1 cells or PBMCs induced ALP activity and its gene expression in HVSMCs and the cells with high expression of ALP calcified their extracellular matrix by the addition of beta-glycerophosphate.	beta-glycerophosphoric acid	174-195	alkaline phosphatase, placental	Homo sapiens	114-117
10733338-7	1999	In a sharp contrast, when the C1 cells were induced to differentiate into osteoblastic cells by the treatment with beta glycerophosphate (betaGP) and ascorbic acid (AA), noggin mRNA expression remained to be barely detectable.	beta-glycerophosphoric acid	115-136	noggin	Mus musculus	170-176
11156469-3	2001	Passaged HMSCs exhibited the osteoblastic phenotype in vitro, including: (a) an increase in alkaline phosphatase (ALP) activity in response to dexamethasone, ascorbic acid, and beta-glycerophosphate: and (b) mRNA expression for markers of osteoblastic lineage (ALP, osteopontin, osteocalcin, and parathyroid hormone-receptor) and BMP-2, -4, and -6 detected by reverse transcription-polymerase chain reaction.	beta-glycerophosphoric acid	177-198	alkaline phosphatase, placental	Homo sapiens	92-112
11156469-3	2001	Passaged HMSCs exhibited the osteoblastic phenotype in vitro, including: (a) an increase in alkaline phosphatase (ALP) activity in response to dexamethasone, ascorbic acid, and beta-glycerophosphate: and (b) mRNA expression for markers of osteoblastic lineage (ALP, osteopontin, osteocalcin, and parathyroid hormone-receptor) and BMP-2, -4, and -6 detected by reverse transcription-polymerase chain reaction.	beta-glycerophosphoric acid	177-198	alkaline phosphatase, placental	Homo sapiens	114-117
10976989-9	2000	We present evidence, using transient transfection and antibody neutralization approaches, that Lefty-1 modulates the induction of alkaline phosphatase (ALP) after treatment of MC3T3-E1 cells with ascorbate and beta-GP.	beta-glycerophosphoric acid	210-217	left right determination factor 1	Mus musculus	95-102
10920219-2	2000	When cultured in the presence of beta-glycerophosphate (GP) and ascorbic acid (AA), MC3T3 cells underwent spontaneous differentiation into osteoblasts which was confirmed as they expressed osteoblast markers such as alkaline phosphatase (ALP), bone sialoprotein (BSP) and osteocalcin (OC).	beta-glycerophosphoric acid	33-54	bone gamma-carboxyglutamate protein 2	Mus musculus	272-283
10920219-2	2000	When cultured in the presence of beta-glycerophosphate (GP) and ascorbic acid (AA), MC3T3 cells underwent spontaneous differentiation into osteoblasts which was confirmed as they expressed osteoblast markers such as alkaline phosphatase (ALP), bone sialoprotein (BSP) and osteocalcin (OC).	beta-glycerophosphoric acid	33-54	bone gamma-carboxyglutamate protein 2	Mus musculus	285-287
10920219-2	2000	When cultured in the presence of beta-glycerophosphate (GP) and ascorbic acid (AA), MC3T3 cells underwent spontaneous differentiation into osteoblasts which was confirmed as they expressed osteoblast markers such as alkaline phosphatase (ALP), bone sialoprotein (BSP) and osteocalcin (OC).	beta-glycerophosphoric acid	56-58	bone gamma-carboxyglutamate protein 2	Mus musculus	272-283
10920219-2	2000	When cultured in the presence of beta-glycerophosphate (GP) and ascorbic acid (AA), MC3T3 cells underwent spontaneous differentiation into osteoblasts which was confirmed as they expressed osteoblast markers such as alkaline phosphatase (ALP), bone sialoprotein (BSP) and osteocalcin (OC).	beta-glycerophosphoric acid	56-58	bone gamma-carboxyglutamate protein 2	Mus musculus	285-287
10571692-7	1999	Expression of type X collagen, type II collagen, aggrecan core protein, and ALP were inhibited significantly between 2 h and 24 h after the addition of beta-GP.	beta-glycerophosphoric acid	152-159	alkaline phosphatase, placental	Homo sapiens	76-79
11394905-3	2001	Culturing retinoic acid treated ES cells in the presence of the osteogenic supplements ascorbic acid and beta-glycerophosphate resulted in the expression of several osteoblast marker genes, osteocalcin, alkaline phosphatase, and osteopontin.	beta-glycerophosphoric acid	105-126	bone gamma-carboxyglutamate protein 2	Mus musculus	190-201
11394905-3	2001	Culturing retinoic acid treated ES cells in the presence of the osteogenic supplements ascorbic acid and beta-glycerophosphate resulted in the expression of several osteoblast marker genes, osteocalcin, alkaline phosphatase, and osteopontin.	beta-glycerophosphoric acid	105-126	secreted phosphoprotein 1	Mus musculus	229-240
10067843-5	1999	Beta-glycerophosphate-induced matrix mineralization in primary osteoblast cultures was associated with significant increases in Phex mRNA and protein.	beta-glycerophosphoric acid	0-21	phosphate regulating endopeptidase homolog, X-linked	Mus musculus	128-132
10067843-9	1999	These results indicate that Phex is a marker of the fully differentiated osteoblast and that its expression is stimulated during beta-glycerophosphate-induced mineralization in primary osteoblast cultures and down-regulated by 1,25-(OH)2D3, an inhibitor of matrix mineralization.	beta-glycerophosphoric acid	129-150	phosphate regulating endopeptidase homolog, X-linked	Mus musculus	28-32
9824538-4	1998	Moreover, EF cells maintained with IL-6/sIL-6R in the presence of ascorbic acid and beta-glycerophosphate expressed osteocalcin messenger RNA (mRNA) by 2 weeks and formed a matrix containing mineralized collagen fibers by 3 weeks.	beta-glycerophosphoric acid	84-105	interleukin 6	Mus musculus	35-39
9824538-4	1998	Moreover, EF cells maintained with IL-6/sIL-6R in the presence of ascorbic acid and beta-glycerophosphate expressed osteocalcin messenger RNA (mRNA) by 2 weeks and formed a matrix containing mineralized collagen fibers by 3 weeks.	beta-glycerophosphoric acid	84-105	bone gamma-carboxyglutamate protein 2	Mus musculus	116-127