PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
3933143-1	1985	Fifteen polychlorinated dibenzofuran (PCDF) congeners were administered in a dose-response fashion to immature male Wistar rats and ED50 values for body weight loss, thymic atrophy and the induction of the hepatic microsomal cytochrome P-448-dependent monooxygenases, aryl hydrocarbon hydroxylase (AHH) and 4-chlorobiphenyl hydroxylase were determined.	Dibenzofurans, Polychlorinated	8-36	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	225-241
3106647-8	1986	These two reciprocal relationships would be the expected result from inhibition of uroporphyrinogen decarboxylase, a known experimental effect of PCB and PCDF in mice.	Dibenzofurans, Polychlorinated	154-158	uroporphyrinogen decarboxylase	Mus musculus	83-113
3933143-2	1985	There was an excellent correlation between the in vivo quantitative structure-activity relationships for these PCDFs and their in vitro activities as AHH inducers in rat hepatoma H-4-II E cells and as ligands for the 2,3,7,8-TCDD receptor protein.	Dibenzofurans, Polychlorinated	111-116	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	150-153
3928357-0	1985	Formation of polychlorinated dibenzofurans and dioxins during combustion, electrical equipment fires and PCB incineration.	Dibenzofurans, Polychlorinated	13-42	pyruvate carboxylase	Homo sapiens	105-108
3933143-5	1985	Since body weight loss and thymic atrophy in the rat are representative toxic responses to PCDFs and related toxic halogenated aryl hydrocarbons, the correlations noted above support the use of the in vitro AHH induction assay as a short term quantitative test system for this class of toxic halogenated aryl hydrocarbons.	Dibenzofurans, Polychlorinated	91-96	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	207-210
3928357-5	1985	From these experiments and from accidents involving PCB fires, it is known that PCDFs are the most important toxic compounds associated with PCBs.	Dibenzofurans, Polychlorinated	80-85	pyruvate carboxylase	Homo sapiens	52-55
3922333-0	1985	Genetically mediated induction of aryl hydrocarbon hydroxylase activity in mice by polychlorinated dibenzofuran isomers and 2,3,7,8-tetrachlorodibenzo-p-dioxin.	Dibenzofurans, Polychlorinated	83-111	cytochrome P450, family 1, subfamily a, polypeptide 1	Mus musculus	34-62
3925096-1	1985	Realization that polychlorinated biphenyl-(PCB)-containing (askarel) transformer fires can produce toxic polychlorinated dibenzofuran (PCDF) and polychlorinated dibenzodioxin (PCDD) isomers has led to efforts to develop guidelines for cleanup of structures contaminated by soot from these fires.	Dibenzofurans, Polychlorinated	105-133	pyruvate carboxylase	Homo sapiens	43-46
3925096-1	1985	Realization that polychlorinated biphenyl-(PCB)-containing (askarel) transformer fires can produce toxic polychlorinated dibenzofuran (PCDF) and polychlorinated dibenzodioxin (PCDD) isomers has led to efforts to develop guidelines for cleanup of structures contaminated by soot from these fires.	Dibenzofurans, Polychlorinated	135-139	pyruvate carboxylase	Homo sapiens	43-46
3922333-4	1985	These results indicate that AHH responsiveness in mice segregates with the induction of AHH activity by PCDF isomers and may also segregate with the toxic potency of the isomers; i.e., toxic potencies of 2,3,7,8-TCDF, 1,2,3,7,8-PCDF, and 2,3,4,7,8-PCDF in AHH-responsive strains of mice may be much greater than those in AHH-nonresponsive strains of mice.	Dibenzofurans, Polychlorinated	104-108	cytochrome P450, family 1, subfamily a, polypeptide 1	Mus musculus	28-31
3922333-4	1985	These results indicate that AHH responsiveness in mice segregates with the induction of AHH activity by PCDF isomers and may also segregate with the toxic potency of the isomers; i.e., toxic potencies of 2,3,7,8-TCDF, 1,2,3,7,8-PCDF, and 2,3,4,7,8-PCDF in AHH-responsive strains of mice may be much greater than those in AHH-nonresponsive strains of mice.	Dibenzofurans, Polychlorinated	104-108	cytochrome P450, family 1, subfamily a, polypeptide 1	Mus musculus	88-91
3922333-4	1985	These results indicate that AHH responsiveness in mice segregates with the induction of AHH activity by PCDF isomers and may also segregate with the toxic potency of the isomers; i.e., toxic potencies of 2,3,7,8-TCDF, 1,2,3,7,8-PCDF, and 2,3,4,7,8-PCDF in AHH-responsive strains of mice may be much greater than those in AHH-nonresponsive strains of mice.	Dibenzofurans, Polychlorinated	104-108	cytochrome P450, family 1, subfamily a, polypeptide 1	Mus musculus	88-91
3922334-0	1985	Genetically mediated induction of aryl hydrocarbon hydroxylase activity in human lymphoblastoid cells by polychlorinated dibenzofuran isomers and 2,3,7,8-tetrachlorodibenzo-p-dioxin.	Dibenzofurans, Polychlorinated	105-133	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	34-62
3922334-6	1985	The experimental evidence indicated that AHH inducibility by the organochlorine compounds reflected the genetic susceptibility of the cells to the phenomenon of induction, and PCDF isomers found at relatively high concentrations in tissues of mammals exerted the highest values of AHH induction.	Dibenzofurans, Polychlorinated	176-180	aryl hydrocarbon receptor repressor	Homo sapiens	281-284
6412664-0	1983	A comparative study of polychlorinated dibenzofurans, polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin on aryl hydrocarbon hydroxylase inducing potency in rats.	Dibenzofurans, Polychlorinated	23-52	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	123-151
2985377-0	1985	Inducing potency of aryl hydrocarbon hydroxylase activity in human lymphoblastoid cells and mice by polychlorinated dibenzofuran congeners.	Dibenzofurans, Polychlorinated	100-128	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	20-48
6464025-0	1984	Polychlorinated dibenzofurans (PCDFs): effects of structure on binding to the 2,3,7,8-TCDD cytosolic receptor protein, AHH induction and toxicity.	Dibenzofurans, Polychlorinated	0-29	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	119-122
6464025-0	1984	Polychlorinated dibenzofurans (PCDFs): effects of structure on binding to the 2,3,7,8-TCDD cytosolic receptor protein, AHH induction and toxicity.	Dibenzofurans, Polychlorinated	31-36	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	119-122
6464025-6	1984	Most of the PCDF structure-activity effects noted above were also observed for the induction of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin O-deethylase (EROD) in rat hepatoma H-4-II-E cells in culture.	Dibenzofurans, Polychlorinated	12-16	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	96-124
6464025-6	1984	Most of the PCDF structure-activity effects noted above were also observed for the induction of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin O-deethylase (EROD) in rat hepatoma H-4-II-E cells in culture.	Dibenzofurans, Polychlorinated	12-16	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	126-129
6464025-8	1984	The in vitro quantitative structure-activity data were complemented by in vivo studies which determined the relative activities of selected PCDFs as inducers of hepatic microsomal cytochrome P-448 dependent monooxygenases and their effects on body weight gain and thymus weights in immature male Wistar rats.	Dibenzofurans, Polychlorinated	140-145	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	180-196
6412664-1	1983	The aryl hydrocarbon hydroxylase (AHH) inducing potency of toxic chlorinated aromatic hydrocarbons such as polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was studied in the young male Wistar rats.	Dibenzofurans, Polychlorinated	107-136	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	4-32
6412664-1	1983	The aryl hydrocarbon hydroxylase (AHH) inducing potency of toxic chlorinated aromatic hydrocarbons such as polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was studied in the young male Wistar rats.	Dibenzofurans, Polychlorinated	107-136	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	34-37
6412664-1	1983	The aryl hydrocarbon hydroxylase (AHH) inducing potency of toxic chlorinated aromatic hydrocarbons such as polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was studied in the young male Wistar rats.	Dibenzofurans, Polychlorinated	138-143	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	4-32
6412664-1	1983	The aryl hydrocarbon hydroxylase (AHH) inducing potency of toxic chlorinated aromatic hydrocarbons such as polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was studied in the young male Wistar rats.	Dibenzofurans, Polychlorinated	138-143	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	34-37
6412664-4	1983	The order of AHH inducing ability was TCDD greater than PCDFs much greater than PCBs in kidney, lung, and liver.	Dibenzofurans, Polychlorinated	56-61	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	13-16
6412664-6	1983	The AHH inducibility in the lung and liver, induced by 15 pure PCDF isomers with varying chlorine substitutions was also examined.	Dibenzofurans, Polychlorinated	63-67	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	4-7
98186-0	1978	Polychlorinated dibenzofuran (PCDF) formation from PCB mixture by heat and oxygen.	Dibenzofurans, Polychlorinated	0-28	pyruvate carboxylase	Homo sapiens	51-54
6818356-4	1982	PCDF congeners identified in the patients showed severe toxicity in rats than this PCB, exhibiting stronger enzyme induction and gravimetric changes of the tissues even at very low doses of 1-10 micrograms/kg.	Dibenzofurans, Polychlorinated	0-4	pyruvate carboxylase	Rattus norvegicus	83-86
6462115-6	1982	As association between dermatological signs and plasma levels of higher homologues of PCBs was suggested, but contaminants which have been reported to be present in commercial PCB mixtures (polychlorinated dibenzofurans) should be considered an etiologic factor or co-factor in the development of "PCB-associated" dermatological findings.	Dibenzofurans, Polychlorinated	190-219	pyruvate carboxylase	Homo sapiens	86-89
6462115-6	1982	As association between dermatological signs and plasma levels of higher homologues of PCBs was suggested, but contaminants which have been reported to be present in commercial PCB mixtures (polychlorinated dibenzofurans) should be considered an etiologic factor or co-factor in the development of "PCB-associated" dermatological findings.	Dibenzofurans, Polychlorinated	190-219	pyruvate carboxylase	Homo sapiens	176-179
98186-0	1978	Polychlorinated dibenzofuran (PCDF) formation from PCB mixture by heat and oxygen.	Dibenzofurans, Polychlorinated	30-34	pyruvate carboxylase	Homo sapiens	51-54
99592-2	1978	PCDFs were about a thousand times more potent than PCBs (Kanechlor-500) as inducers of cytochrome P-450.	Dibenzofurans, Polychlorinated	0-5	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	87-103
99592-3	1978	Rats given 10 microgram/kg of PCDFs intraperitoneally for 3 days showed significantly increased hepatic cytochrome P-450 levels.	Dibenzofurans, Polychlorinated	30-35	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	104-120
99592-9	1978	Following three daily doses of PCDFs (100 microgram/kg), cytochrome P-450 level and p-nitroanisole demethylase activity remained elevated for over 15 days, with a decrease to control levels after 30 days.	Dibenzofurans, Polychlorinated	31-36	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	57-73
27613629-2	2018	In vitro bioassays, based on 7-ethoxyresorufin-O-deethylase (EROD) and the activity of cytochrome P450 1A1 and the aryl hydrogen receptor (AhR) pathway, are employed for the evaluation of bioanalytical equivalents (BEQ) of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) from a wide variety of sample matrices.	Dibenzofurans, Polychlorinated	266-295	aryl hydrocarbon receptor	Homo sapiens	139-142
406956-0	1977	Detailed examination of polychlorinated dibenzofurans in PCB preparations and Kanemi yusho oil.	Dibenzofurans, Polychlorinated	24-53	pyruvate carboxylase	Homo sapiens	57-60
32240844-9	2020	Conversely, serum cytotoxic T lymphocyte-associated antigen-4 (CTLA-4), which is a cytokine related to activated NK cells, was higher in Yusho patients than in healthy subjects and was positively correlated with PCDF blood levels.	Dibenzofurans, Polychlorinated	212-216	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	18-61
32240844-9	2020	Conversely, serum cytotoxic T lymphocyte-associated antigen-4 (CTLA-4), which is a cytokine related to activated NK cells, was higher in Yusho patients than in healthy subjects and was positively correlated with PCDF blood levels.	Dibenzofurans, Polychlorinated	212-216	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	63-69
31444645-6	2019	High sediment PCDD/F concentrations have persisted in Boat Harbour despite implementation of Pulp and Paper Mill Effluent Chlorinated Dioxins and Furans Regulations in 1992.	Dibenzofurans, Polychlorinated	14-20	ataxin 1 like	Homo sapiens	54-58
27613629-2	2018	In vitro bioassays, based on 7-ethoxyresorufin-O-deethylase (EROD) and the activity of cytochrome P450 1A1 and the aryl hydrogen receptor (AhR) pathway, are employed for the evaluation of bioanalytical equivalents (BEQ) of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) from a wide variety of sample matrices.	Dibenzofurans, Polychlorinated	297-302	aryl hydrocarbon receptor	Homo sapiens	139-142
29978112-0	2017	Application of the AhR Reporter Gene Assay for the Determination of PCDD/Fs and DL-PCBs in Feed Samples.	Dibenzofurans, Polychlorinated	68-75	aryl hydrocarbon receptor	Homo sapiens	19-22
29978112-5	2017	The article presents AhR based reporter gene bioassay method for PCDD/Fs and DL-PCBs analysis in feed and its validation results.	Dibenzofurans, Polychlorinated	65-72	aryl hydrocarbon receptor	Homo sapiens	21-24
23424013-1	2013	Polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) cause toxic effects after binding to an intracellular cytosolic receptor called the aryl hydrocarbon receptor (AhR).	Dibenzofurans, Polychlorinated	40-69	aryl hydrocarbon receptor	Homo sapiens	200-225
23690076-4	2013	RePs of 21 polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls that exhibit effects mediated through the AhR were determined by use of the H4IIE-luc assay.	Dibenzofurans, Polychlorinated	46-75	aryl hydrocarbon receptor	Homo sapiens	161-164
23424013-1	2013	Polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) cause toxic effects after binding to an intracellular cytosolic receptor called the aryl hydrocarbon receptor (AhR).	Dibenzofurans, Polychlorinated	40-69	aryl hydrocarbon receptor	Homo sapiens	227-230
23424013-1	2013	Polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) cause toxic effects after binding to an intracellular cytosolic receptor called the aryl hydrocarbon receptor (AhR).	Dibenzofurans, Polychlorinated	71-76	aryl hydrocarbon receptor	Homo sapiens	200-225
23424013-1	2013	Polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) cause toxic effects after binding to an intracellular cytosolic receptor called the aryl hydrocarbon receptor (AhR).	Dibenzofurans, Polychlorinated	71-76	aryl hydrocarbon receptor	Homo sapiens	227-230
22722001-2	2012	Although several research groups have confirmed that polychlorinated dibenzofurans (PCDFs) are formed from PCBs during the thermal desorption of sediments contaminated with PCB, the formation pathways remain poorly understood.	Dibenzofurans, Polychlorinated	53-82	pyruvate carboxylase	Homo sapiens	107-110
22722001-2	2012	Although several research groups have confirmed that polychlorinated dibenzofurans (PCDFs) are formed from PCBs during the thermal desorption of sediments contaminated with PCB, the formation pathways remain poorly understood.	Dibenzofurans, Polychlorinated	84-89	pyruvate carboxylase	Homo sapiens	107-110
19850319-7	2010	Pearson and Spearman correlation analyses showed a relationship between the total TEQ concentration of PCDDs, PCDFs, and dioxin-like PCBs and the total concentration of 56 non-dioxin-like PCB congeners in maternal blood, and also showed an association between the total TEQ concentration of these dioxin-like compounds and the total concentration of 56 PCB congeners in breast milk.	Dibenzofurans, Polychlorinated	110-115	pyruvate carboxylase	Homo sapiens	188-191
22564455-5	2012	Superoxide dismutase (SOD) and peroxidase (POD) exhibited peak enzyme activities at the PCDD/Fs concentration of 1000ng WHO(98)-TEQg(-1)fresh weight.	Dibenzofurans, Polychlorinated	88-95	peroxidase N1	Nicotiana tabacum	31-41
22564455-5	2012	Superoxide dismutase (SOD) and peroxidase (POD) exhibited peak enzyme activities at the PCDD/Fs concentration of 1000ng WHO(98)-TEQg(-1)fresh weight.	Dibenzofurans, Polychlorinated	88-95	peroxidase N1	Nicotiana tabacum	43-46
22428884-1	2012	The transgenic tobacco plant XD4V-26 carrying the recombinant mouse aryl hydrocarbon receptor XD4V-mediated beta-glucuronidase (GUS) reporter gene expression system was used for assay of dioxins and dioxin-like compounds consisting of polychlorodibenzo-p-dioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls (Co-PCBs) in actually contaminated soils.	Dibenzofurans, Polychlorinated	264-293	aryl-hydrocarbon receptor	Mus musculus	68-93
20821598-1	2010	In birds, activation of the aryl hydrocarbon receptor (AhR) by some polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) results in induction of cytochrome P4501A (CYP1A) expression.	Dibenzofurans, Polychlorinated	114-143	aryl hydrocarbon receptor 1 alpha	Gallus gallus	28-53
20821598-1	2010	In birds, activation of the aryl hydrocarbon receptor (AhR) by some polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) results in induction of cytochrome P4501A (CYP1A) expression.	Dibenzofurans, Polychlorinated	114-143	aryl hydrocarbon receptor 1 alpha	Gallus gallus	55-58
20821598-1	2010	In birds, activation of the aryl hydrocarbon receptor (AhR) by some polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) results in induction of cytochrome P4501A (CYP1A) expression.	Dibenzofurans, Polychlorinated	145-150	aryl hydrocarbon receptor 1 alpha	Gallus gallus	28-53
20821598-1	2010	In birds, activation of the aryl hydrocarbon receptor (AhR) by some polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) results in induction of cytochrome P4501A (CYP1A) expression.	Dibenzofurans, Polychlorinated	145-150	aryl hydrocarbon receptor 1 alpha	Gallus gallus	55-58
22022789-1	2012	The transgenic tobacco plant XD4V-26 carrying the recombinant mouse aryl hydrocarbon receptor XD4V-mediated beta-glucuronidase (GUS) reporter gene expression system was used for assay of dioxins and dioxin-like compounds consisting of polychlorinated dibenzeno-p-dioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls (Co-PCBs) in actually contaminated soils.	Dibenzofurans, Polychlorinated	272-301	aryl-hydrocarbon receptor	Mus musculus	68-93
21913657-4	2011	Since PPARalpha has a role in mediating some of these effects, and there is some overlap in the type of toxicities elicited by perfluoroalkyl chemicals, it has been suggested that a scaling system analogous to the toxic equivalency factor (TEF) system used for polychlorinated dibenzo-p-dioxins (PCDD), polychlorinated dibenzofurans (PCDF), and polychlorinated biphenyls (PCB) could be used for perfluoroalkyl chemicals.	Dibenzofurans, Polychlorinated	303-332	TEF transcription factor, PAR bZIP family member	Homo sapiens	214-238
21913657-4	2011	Since PPARalpha has a role in mediating some of these effects, and there is some overlap in the type of toxicities elicited by perfluoroalkyl chemicals, it has been suggested that a scaling system analogous to the toxic equivalency factor (TEF) system used for polychlorinated dibenzo-p-dioxins (PCDD), polychlorinated dibenzofurans (PCDF), and polychlorinated biphenyls (PCB) could be used for perfluoroalkyl chemicals.	Dibenzofurans, Polychlorinated	334-338	TEF transcription factor, PAR bZIP family member	Homo sapiens	214-238
19440495-7	2009	By analyzing each component of metabolic syndrome separately, the DL-PCB TEQs and total TEQs were associated with all components, and the odds ratios (ORs) in the highest quartile of DL-PCB TEQs in four of the five components were higher than those for PCDDs or PCDFs.	Dibenzofurans, Polychlorinated	262-267	pyruvate carboxylase	Homo sapiens	69-72
19072627-1	2009	The standard gas-phase enthalpies of formation of polychlorinated dibenzofurans (PCDFs) have been predicted by using G3XMP2 model chemistry, density functional theory (DFT), and second-order Muller-Plesset (MP2) theory, coupled with isodesmic reactions.	Dibenzofurans, Polychlorinated	50-79	tryptase pseudogene 1	Homo sapiens	120-123
19072627-1	2009	The standard gas-phase enthalpies of formation of polychlorinated dibenzofurans (PCDFs) have been predicted by using G3XMP2 model chemistry, density functional theory (DFT), and second-order Muller-Plesset (MP2) theory, coupled with isodesmic reactions.	Dibenzofurans, Polychlorinated	81-86	tryptase pseudogene 1	Homo sapiens	120-123
18281078-4	2008	However, the repeatability of the ER-H test decreased with increases in the hydrophobicity of the studied compounds; the standard deviations for PCDEs, PCDFs and PCDDs ranged from 53% to 110%, 57% to 77% and 110% to 130%, respectively.	Dibenzofurans, Polychlorinated	152-157	ERH mRNA splicing and mitosis factor	Homo sapiens	34-38
18470296-9	2008	CONCLUSION: High levels of PCB/PCDF exposure had some adverse effects on pregnancy outcome in Yusho women.	Dibenzofurans, Polychlorinated	31-35	pyruvate carboxylase	Homo sapiens	27-30
18649880-6	2008	Simple and partial correlation analyses revealed that HbA1c correlated with the accumulated TEQs of PCDDs+PCDFs, dioxin-like PCBs and total dioxins.	Dibenzofurans, Polychlorinated	106-111	hemoglobin subunit alpha 1	Homo sapiens	54-58
16628245-14	2006	PCB 126 was selected for study by the National Toxicology Program as a part of the dioxin TEF evaluation to assess the cancer risk posed by complex mixtures of polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs.	Dibenzofurans, Polychlorinated	200-229	pyruvate carboxylase	Rattus norvegicus	0-3
17208274-11	2007	In conclusion, the 1999 PCB/dioxin incident was traceable in the plasma profiles (rise of the two specific PCDF congeners), but comparison of the results for both years indicates that the changes were too small to cause an adverse public health effect.	Dibenzofurans, Polychlorinated	107-111	pyruvate carboxylase	Homo sapiens	24-27
16835634-14	2006	PCB 153 was selected for study by the National Toxicology Program as a part of the dioxin TEF evaluation to assess the cancer risk posed by complex mixtures of polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs).	Dibenzofurans, Polychlorinated	200-229	pyruvate carboxylase	Rattus norvegicus	0-3
16835634-14	2006	PCB 153 was selected for study by the National Toxicology Program as a part of the dioxin TEF evaluation to assess the cancer risk posed by complex mixtures of polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs).	Dibenzofurans, Polychlorinated	231-236	pyruvate carboxylase	Rattus norvegicus	0-3
17642293-1	2007	To evaluate chronic effect of polychlorinated biphenyls (PCB) and polychlorinated dibenzofurans (PCDF) on sex hormones and prolactin, serum levels of estradiol, progesterone and prolactin were studied in 71 female patients with Yusho and 23 controls in 2006.	Dibenzofurans, Polychlorinated	97-101	prolactin	Homo sapiens	123-132
16628245-14	2006	PCB 126 was selected for study by the National Toxicology Program as a part of the dioxin TEF evaluation to assess the cancer risk posed by complex mixtures of polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs.	Dibenzofurans, Polychlorinated	231-236	pyruvate carboxylase	Rattus norvegicus	0-3
15858227-1	2005	Non-ortho polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) are ubiquitous environmental contaminants that exert their toxicity mostly through activation of the aryl-hydrocarbon receptor (AhR), and are referred to as AhR agonists.	Dibenzofurans, Polychlorinated	88-117	aryl hydrocarbon receptor	Rattus norvegicus	227-252
15858227-1	2005	Non-ortho polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) are ubiquitous environmental contaminants that exert their toxicity mostly through activation of the aryl-hydrocarbon receptor (AhR), and are referred to as AhR agonists.	Dibenzofurans, Polychlorinated	88-117	aryl hydrocarbon receptor	Rattus norvegicus	254-257
15858227-1	2005	Non-ortho polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) are ubiquitous environmental contaminants that exert their toxicity mostly through activation of the aryl-hydrocarbon receptor (AhR), and are referred to as AhR agonists.	Dibenzofurans, Polychlorinated	88-117	aryl hydrocarbon receptor	Rattus norvegicus	283-286
15858227-1	2005	Non-ortho polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) are ubiquitous environmental contaminants that exert their toxicity mostly through activation of the aryl-hydrocarbon receptor (AhR), and are referred to as AhR agonists.	Dibenzofurans, Polychlorinated	119-124	aryl hydrocarbon receptor	Rattus norvegicus	227-252
15858227-1	2005	Non-ortho polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) are ubiquitous environmental contaminants that exert their toxicity mostly through activation of the aryl-hydrocarbon receptor (AhR), and are referred to as AhR agonists.	Dibenzofurans, Polychlorinated	119-124	aryl hydrocarbon receptor	Rattus norvegicus	254-257
15858227-1	2005	Non-ortho polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) are ubiquitous environmental contaminants that exert their toxicity mostly through activation of the aryl-hydrocarbon receptor (AhR), and are referred to as AhR agonists.	Dibenzofurans, Polychlorinated	119-124	aryl hydrocarbon receptor	Rattus norvegicus	283-286
15720127-3	2005	Multiple regression analysis demonstrated that the difference in the potency of aryl hydrocarbon hydroxylase (AHH) and 7-ethoxyresorufin O-deethylase (EROD) inductions is mostly determined by the polarizabilities of PCDFs.	Dibenzofurans, Polychlorinated	216-221	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	80-108
15720127-4	2005	This suggests that the interaction of a PCDF with the aryl hydrocarbon receptor (AhR) and its interaction with surrounding molecules in the cytosol are dispersion interactions rather than electrostatic interactions.	Dibenzofurans, Polychlorinated	40-44	aryl hydrocarbon receptor	Homo sapiens	54-79
15720127-4	2005	This suggests that the interaction of a PCDF with the aryl hydrocarbon receptor (AhR) and its interaction with surrounding molecules in the cytosol are dispersion interactions rather than electrostatic interactions.	Dibenzofurans, Polychlorinated	40-44	aryl hydrocarbon receptor	Homo sapiens	81-84
15720127-7	2005	A mathematical model is also used to study the differences in AhR binding between PCDFs.	Dibenzofurans, Polychlorinated	82-87	aryl hydrocarbon receptor	Homo sapiens	62-65
12916318-6	2003	To examine TCDD and PCDDs/PCDFs mixture action on cytochrome P450 side change cleavage enzyme (P450 scc) and 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) activity the placental cells were cultured either in basal conditions or with the addition of 25-hydroxycholesterol (25-OH) or pregnenolone (P5).	Dibenzofurans, Polychlorinated	26-31	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	Homo sapiens	146-156
15025505-3	2004	QSARs were developed relating aryl hydrocarbon receptor (AhR) binding affinities, aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase induction potencies of PCDFs with DFT descriptors, hydrophobicity, and steric parameters.	Dibenzofurans, Polychlorinated	167-172	aryl hydrocarbon receptor	Homo sapiens	57-60
15025505-4	2004	These QSARs explain around 75% of variation in AhR binding affinities of PCDFs.	Dibenzofurans, Polychlorinated	73-78	aryl hydrocarbon receptor	Homo sapiens	47-50
14632461-10	2003	The approach was applied to published data for binding of 34 polychlorinated dibenzofurans to the aryl hydrocarbon receptor.	Dibenzofurans, Polychlorinated	61-90	aryl hydrocarbon receptor	Homo sapiens	98-123
14524447-4	2003	The total amount of PCDD/F increased from 2.0 ng/kg of ash (0.05 ng of TE/kg of ash, using WHO-TEF) for untreated radiata pine to a maximum of 2700 ng/kg of ash (78 ng of TE/kg of ash) for 0.94% CCA.	Dibenzofurans, Polychlorinated	20-26	TEF transcription factor, PAR bZIP family member	Homo sapiens	95-98
12618327-2	2003	Exposure to a complex environmental PCB/PCDD/PCDF mixture (polychlorinated biphenyls/polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans) during the irradiation phase of photocarcinogenesis was associated with significant (P < or = 0.001) reductions in papilloma incidence and squamous cell carcinoma multiplicity at irradiated skin sites.	Dibenzofurans, Polychlorinated	119-148	pyruvate carboxylase	Mus musculus	36-39
21781665-4	1996	In the PCB mixtures Arochlor 1254 and Clophen A50, potent dioxin-like non-ortho PCBs and polychlorinated dibenzofurans (PCDFs) were found in minor amounts.	Dibenzofurans, Polychlorinated	89-118	pyruvate carboxylase	Rattus norvegicus	7-10
11280982-6	2001	This paper reports on a bench-scale experimental study to characterize a newly built reactor system that was built to: produce levels and distributions of PCDD/F production similar to those achieved by previous researchers; verify similar responses to changes in independent variables; examine the hypothesis that PCB formation rates exhibit trends similar to PCDD/F formation rates as reactor variables are changed; and begin to explore the dependence of PCB formation on temperature and precursor type.	Dibenzofurans, Polychlorinated	360-366	pyruvate carboxylase	Homo sapiens	314-317
10464071-6	1999	Lifetime prevalence of chloracne, abnormal nails, hyperkeratosis, skin allergy, goiter, headache, gum pigmentation, and broken teeth were observed more frequently in the PCB/PCDF-exposed men and women.	Dibenzofurans, Polychlorinated	174-178	pyruvate carboxylase	Homo sapiens	170-173
12627635-1	2003	Four spectroscopic data-activity relationship (SDAR) models for polychlorinated dibenzofurans (PCDFs) and dibenzodioxins (PCDDs) binding to the aryl hydrocarbon receptor (AhR) have been developed based on simulated 13C nuclear magnetic resonance (NMR) data.	Dibenzofurans, Polychlorinated	64-93	aryl hydrocarbon receptor	Homo sapiens	144-169
12627635-1	2003	Four spectroscopic data-activity relationship (SDAR) models for polychlorinated dibenzofurans (PCDFs) and dibenzodioxins (PCDDs) binding to the aryl hydrocarbon receptor (AhR) have been developed based on simulated 13C nuclear magnetic resonance (NMR) data.	Dibenzofurans, Polychlorinated	64-93	aryl hydrocarbon receptor	Homo sapiens	171-174
12627635-1	2003	Four spectroscopic data-activity relationship (SDAR) models for polychlorinated dibenzofurans (PCDFs) and dibenzodioxins (PCDDs) binding to the aryl hydrocarbon receptor (AhR) have been developed based on simulated 13C nuclear magnetic resonance (NMR) data.	Dibenzofurans, Polychlorinated	95-100	aryl hydrocarbon receptor	Homo sapiens	144-169
12627635-1	2003	Four spectroscopic data-activity relationship (SDAR) models for polychlorinated dibenzofurans (PCDFs) and dibenzodioxins (PCDDs) binding to the aryl hydrocarbon receptor (AhR) have been developed based on simulated 13C nuclear magnetic resonance (NMR) data.	Dibenzofurans, Polychlorinated	95-100	aryl hydrocarbon receptor	Homo sapiens	171-174
12627635-6	2003	We used each appropriate SDAR model to classify 41 PCDD and/or 121 PCDF compounds with unknown binding affinities to the AhR.	Dibenzofurans, Polychlorinated	67-71	aryl hydrocarbon receptor	Homo sapiens	121-124
12627635-7	2003	The SDAR models provide a rapid, simple, and valid way to model the PCDF and PCDD binding activity in relation to the AhR.	Dibenzofurans, Polychlorinated	68-72	aryl hydrocarbon receptor	Homo sapiens	118-121
12685749-2	2003	A model equation between GC-RIs (= RI) and these physico-chemical properties (K) of PCDFs was in a form of log K = aRI2 + bRI + c with correlation coefficients (R2) greater than 0.94, except H(c).	Dibenzofurans, Polychlorinated	84-89	ariadne RBR E3 ubiquitin protein ligase 2	Homo sapiens	115-119
11604033-1	2001	Quantitative spectroscopic data-activity relationship (QSDAR) models for polychlorinated dibenzofurans (PCDFs), dibenzodioxins (PCDDs), and biphenyls (PCBs) binding to the aryl hydrocarbon receptor (AhR) have been developed based on simulated (13)C nuclear magnetic resonance (NMR) data.	Dibenzofurans, Polychlorinated	73-102	aryl hydrocarbon receptor	Homo sapiens	172-197
11604033-1	2001	Quantitative spectroscopic data-activity relationship (QSDAR) models for polychlorinated dibenzofurans (PCDFs), dibenzodioxins (PCDDs), and biphenyls (PCBs) binding to the aryl hydrocarbon receptor (AhR) have been developed based on simulated (13)C nuclear magnetic resonance (NMR) data.	Dibenzofurans, Polychlorinated	73-102	aryl hydrocarbon receptor	Homo sapiens	199-202
11604033-11	2001	The QSDAR models provide a rapid, simple and valid way to model the PCDF, PCDD, and PCB binding activity in relation to the aryl hydrocarbon receptor (AhR).	Dibenzofurans, Polychlorinated	68-72	aryl hydrocarbon receptor	Homo sapiens	124-149
11604033-11	2001	The QSDAR models provide a rapid, simple and valid way to model the PCDF, PCDD, and PCB binding activity in relation to the aryl hydrocarbon receptor (AhR).	Dibenzofurans, Polychlorinated	68-72	aryl hydrocarbon receptor	Homo sapiens	151-154
11337868-1	2001	Induction of cytochrome P4501A (CYP1A) mRNA by polychlorinated dibenzo-p-dioxin (PCDD), polychlorinated dibenzofuran (PCDF), and polychlorinated biphenyl (PCB) congeners was measured in a zebrafish liver (ZF-L) cell line.	Dibenzofurans, Polychlorinated	88-116	cytochrome P450, family 1, subfamily A	Danio rerio	13-30
11337868-1	2001	Induction of cytochrome P4501A (CYP1A) mRNA by polychlorinated dibenzo-p-dioxin (PCDD), polychlorinated dibenzofuran (PCDF), and polychlorinated biphenyl (PCB) congeners was measured in a zebrafish liver (ZF-L) cell line.	Dibenzofurans, Polychlorinated	88-116	cytochrome P450, family 1, subfamily A	Danio rerio	32-37
11337868-1	2001	Induction of cytochrome P4501A (CYP1A) mRNA by polychlorinated dibenzo-p-dioxin (PCDD), polychlorinated dibenzofuran (PCDF), and polychlorinated biphenyl (PCB) congeners was measured in a zebrafish liver (ZF-L) cell line.	Dibenzofurans, Polychlorinated	118-122	cytochrome P450, family 1, subfamily A	Danio rerio	13-30
11337868-1	2001	Induction of cytochrome P4501A (CYP1A) mRNA by polychlorinated dibenzo-p-dioxin (PCDD), polychlorinated dibenzofuran (PCDF), and polychlorinated biphenyl (PCB) congeners was measured in a zebrafish liver (ZF-L) cell line.	Dibenzofurans, Polychlorinated	118-122	cytochrome P450, family 1, subfamily A	Danio rerio	32-37
10473785-3	1999	The content of polychlorinated dibenzofurans (PCDFs) and dibenzo-p-dioxins (PCDDs) in the bleaching filtrate in terms of the nordic toxicity equivalent (N-TEQ) was 33.5, 1.15, 0.56, and 0.014 pg/L for the E, C, H1, and H2 bleaching stages, respectively.	Dibenzofurans, Polychlorinated	15-44	enoyl-CoA hydratase 1	Homo sapiens	205-221
15992156-6	1999	Alternate-substituted (1,3,6,8- and 2,4,6,8-) alkyl polychlorinated dibenzofurans (PCDFs) and substituted diindolylmethanes (DIMs) bind the AhR and induce a pattern of AhR-oestrogen receptor (ER) inhibitory cross-talk similar to that observed for TCDD including inhibition of mammary tumour growth at doses < 1.0 mg/kg/day.	Dibenzofurans, Polychlorinated	83-88	aryl hydrocarbon receptor	Homo sapiens	140-143
15992156-6	1999	Alternate-substituted (1,3,6,8- and 2,4,6,8-) alkyl polychlorinated dibenzofurans (PCDFs) and substituted diindolylmethanes (DIMs) bind the AhR and induce a pattern of AhR-oestrogen receptor (ER) inhibitory cross-talk similar to that observed for TCDD including inhibition of mammary tumour growth at doses < 1.0 mg/kg/day.	Dibenzofurans, Polychlorinated	83-88	aryl hydrocarbon receptor	Homo sapiens	168-171
21781665-4	1996	In the PCB mixtures Arochlor 1254 and Clophen A50, potent dioxin-like non-ortho PCBs and polychlorinated dibenzofurans (PCDFs) were found in minor amounts.	Dibenzofurans, Polychlorinated	120-125	pyruvate carboxylase	Rattus norvegicus	7-10
8310450-1	1994	A considerable body of research over the past fifteen years establishes that in laboratory animals the Ah (aromatic hydrocarbon) receptor (AhR) mediates most, if not all, toxic effects of halogenated aromatic hydrocarbons such as polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and polyhalogenated biphenyls.	Dibenzofurans, Polychlorinated	265-294	aryl hydrocarbon receptor	Homo sapiens	103-137
7992230-4	1994	Exposure to contaminated rice oil containing large doses of polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs) also resulted in massive elevation of CYP 1A1 in human placenta but formation of DNA adducts directly from this exposure has not previously been reported.	Dibenzofurans, Polychlorinated	97-126	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	173-180
8310450-1	1994	A considerable body of research over the past fifteen years establishes that in laboratory animals the Ah (aromatic hydrocarbon) receptor (AhR) mediates most, if not all, toxic effects of halogenated aromatic hydrocarbons such as polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and polyhalogenated biphenyls.	Dibenzofurans, Polychlorinated	265-294	aryl hydrocarbon receptor	Homo sapiens	139-142
7992230-4	1994	Exposure to contaminated rice oil containing large doses of polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs) also resulted in massive elevation of CYP 1A1 in human placenta but formation of DNA adducts directly from this exposure has not previously been reported.	Dibenzofurans, Polychlorinated	128-133	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	173-180
7992230-5	1994	The purpose for comparing the two populations was to test the hypothesis that if CYP 1A1 induction results in the metabolic activation of endogenous compounds, then DNA adducts should also be present in PCB/PCDF exposed tissues exhibiting high CYP 1A1 activity and some of the adducts detected in the placental DNA from smokers may be identified as those derived from the metabolic activation of endogenous compounds.	Dibenzofurans, Polychlorinated	207-211	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	81-88
2718174-2	1989	Like TCDD, these polychlorinated dibenzofurans (PCDFs) induce hepatic benzo[a]pyrene hydroxylase activity (BPH) and possess high affinity for the Ah receptor.	Dibenzofurans, Polychlorinated	17-46	aryl-hydrocarbon receptor	Mus musculus	146-157
7992230-5	1994	The purpose for comparing the two populations was to test the hypothesis that if CYP 1A1 induction results in the metabolic activation of endogenous compounds, then DNA adducts should also be present in PCB/PCDF exposed tissues exhibiting high CYP 1A1 activity and some of the adducts detected in the placental DNA from smokers may be identified as those derived from the metabolic activation of endogenous compounds.	Dibenzofurans, Polychlorinated	207-211	pyruvate carboxylase	Homo sapiens	203-206
7992230-5	1994	The purpose for comparing the two populations was to test the hypothesis that if CYP 1A1 induction results in the metabolic activation of endogenous compounds, then DNA adducts should also be present in PCB/PCDF exposed tissues exhibiting high CYP 1A1 activity and some of the adducts detected in the placental DNA from smokers may be identified as those derived from the metabolic activation of endogenous compounds.	Dibenzofurans, Polychlorinated	207-211	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	244-251
8391339-9	1993	Moreover, the developed methodology for AHH and EROD induction by PCDDs is shown to apply to polychlorinated dibenzofurans, thus, eliminating cross-class comparison problem of traditional structure-activity studies.	Dibenzofurans, Polychlorinated	93-122	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	40-43
1336723-10	1992	A number of structural analogs of TCDD, such as the polychlorinated dibenzofurans, also interact with the Ah receptor, and they produce the same spectrum of responses as TCDD in animal and cell models.	Dibenzofurans, Polychlorinated	52-81	aryl hydrocarbon receptor	Homo sapiens	106-117
8394802-6	1993	Binding of PCDDs and PCDFs to a receptor protein, termed the dioxin or Ah receptor, is necessary for most biological and toxic responses.	Dibenzofurans, Polychlorinated	21-26	aryl hydrocarbon receptor	Homo sapiens	71-82
8394802-10	1993	The sequence in events initiated by the Ah receptor interacting with dioxin-responsive genes and ending with altered patterns of differentiation and growth must be sought in order to understand tissue, species, sex, and interindividual variation in biological responses and the health risk posed by PCDDs and PCDFs.	Dibenzofurans, Polychlorinated	309-314	aryl hydrocarbon receptor	Homo sapiens	40-51
34693345-3	2021	Findings revealed that some PCDF congeners exhibit high probabilities of binding to androgen receptor in its agonistic and antagonistic conformations.	Dibenzofurans, Polychlorinated	28-32	androgen receptor	Homo sapiens	84-101
34693345-4	2021	In depth molecular docking analysis of the receptor-ligand complexes formed by PCDFs with androgen receptor in its agonistic and antagonistic conformations showed that, these complexes were stabilized by electrostatic, van der Waals, pi-effect and hydrophobic interactions.	Dibenzofurans, Polychlorinated	79-84	androgen receptor	Homo sapiens	90-107
34693345-6	2021	This computational study suggests that some PCDF congeners may act as agonists and antagonists of androgen receptor in humans and wildlife via inapproprate binding to the receptor.	Dibenzofurans, Polychlorinated	44-48	androgen receptor	Homo sapiens	98-115
2718174-2	1989	Like TCDD, these polychlorinated dibenzofurans (PCDFs) induce hepatic benzo[a]pyrene hydroxylase activity (BPH) and possess high affinity for the Ah receptor.	Dibenzofurans, Polychlorinated	48-53	aryl-hydrocarbon receptor	Mus musculus	146-157
2825595-0	1987	Synthesis and aryl hydrocarbon receptor binding properties of radiolabeled polychlorinated dibenzofuran congeners.	Dibenzofurans, Polychlorinated	75-103	aryl hydrocarbon receptor	Rattus norvegicus	14-39
3188012-2	1988	Related in structure and toxicity to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), PCDFs have been detected in municipal and industrial effluents, PCB mixtures, and in a variety of antiseptics and preservative solutions.	Dibenzofurans, Polychlorinated	81-86	pyruvate carboxylase	Rattus norvegicus	145-148
2834196-7	1987	Our results revealed a dramatic elevation in placental AHH activity in samples from PCB/PCDF-exposed women.	Dibenzofurans, Polychlorinated	88-92	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	55-58
2834196-7	1987	Our results revealed a dramatic elevation in placental AHH activity in samples from PCB/PCDF-exposed women.	Dibenzofurans, Polychlorinated	88-92	pyruvate carboxylase	Homo sapiens	84-87
2834196-10	1987	EGF receptor-mediated autophosphorylation capacity was significantly diminished in PCB/PCDF placentae, but this effect was not associated with changes in plasma membrane EGF receptor binding properties (Kd and Bmax).	Dibenzofurans, Polychlorinated	87-91	epidermal growth factor receptor	Homo sapiens	0-12
2834196-10	1987	EGF receptor-mediated autophosphorylation capacity was significantly diminished in PCB/PCDF placentae, but this effect was not associated with changes in plasma membrane EGF receptor binding properties (Kd and Bmax).	Dibenzofurans, Polychlorinated	87-91	pyruvate carboxylase	Homo sapiens	83-86
19994994-0	1987	Polychlorinated Dibenzofurans and Dibenzo-p -dioxins and other Chlorinated Contaminants in Cow Milk from Various Locations in Switzerland.	Dibenzofurans, Polychlorinated	0-29	Weaning weight-maternal milk	Bos taurus	95-99