PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
19717617-3	2009	To determine which protein directly binds to jasmonoyl-isoleucine (JA-Ile)/coronatine (COR) and serves as a receptor for jasmonate, we built a high-quality structural model of COI1 and performed molecular modeling of COI1-jasmonate interactions.	jasmonoyl-isoleucine	67-73	RNI-like superfamily protein	Arabidopsis thaliana	176-180
25648767-4	2015	When heterologously expressed in oocytes, GTR1 transports jasmonoyl-isoleucine and gibberellin in addition to glucosinolates.	jasmonoyl-isoleucine	58-78	Major facilitator superfamily protein	Arabidopsis thaliana	42-46
24859518-5	2014	The neomycin-dependent reduced JA-Ile level is partially due to increased CYP94B3 expression and subsequent JA-Ile turn-over to12-hydroxy-JA-Ile.	jasmonoyl-isoleucine	31-37	cytochrome P450, family 94, subfamily B, polypeptide 3	Arabidopsis thaliana	74-81
19740496-4	2009	The coi1 mutant identified the F-box protein that is now known to be the receptor for jasmonoyl-isoleucine, the active form of jasmonate hormone.	jasmonoyl-isoleucine	86-106	RNI-like superfamily protein	Arabidopsis thaliana	4-8
23852442-2	2013	Jasmonoyl-isoleucine, an amino acid conjugate of jasmonic acid (JA), is perceived by the protein complex composed of the F-box protein CORONATINE INSENSITIVE1 (COI1) and JASMONATE ZIM DOMAIN (JAZ) proteins, leading to the ubiquitin-dependent degradation of JAZ proteins.	jasmonoyl-isoleucine	0-20	RNI-like superfamily protein	Arabidopsis thaliana	160-164
22215670-2	2012	Jasmonoyl-isoleucine (JA-Ile) has been identified as a specific ligand binding the COI1-JAZ co-receptor to relieve repression of jasmonate responses.	jasmonoyl-isoleucine	0-20	RNI-like superfamily protein	Arabidopsis thaliana	83-87
20025249-3	2010	Mutants of Arabidopsis and tomato have helped to define the pathway for synthesis of jasmonoyl-isoleucine (JA-Ile), the active form of JA, and to identify the F-box protein COI1 as central regulatory unit.	jasmonoyl-isoleucine	85-105	coronatine-insensitive 1	Solanum lycopersicum	173-177
18547396-4	2008	We have recently shown that jasmonoyl isoleucine (JA-Ile) promotes physical interaction between Arabidopsis JAZ1 and COI1 (the F-box component of SCF(COI1)) proteins, and that the JA-Ile-dependent COI1-JAZ1 interaction could be reconstituted in yeast cells (i.e. in the absence of other plant proteins).	jasmonoyl-isoleucine	28-48	jasmonate-zim-domain protein 1	Arabidopsis thaliana	108-112
18547396-4	2008	We have recently shown that jasmonoyl isoleucine (JA-Ile) promotes physical interaction between Arabidopsis JAZ1 and COI1 (the F-box component of SCF(COI1)) proteins, and that the JA-Ile-dependent COI1-JAZ1 interaction could be reconstituted in yeast cells (i.e. in the absence of other plant proteins).	jasmonoyl-isoleucine	28-48	RNI-like superfamily protein	Arabidopsis thaliana	117-121
18547396-4	2008	We have recently shown that jasmonoyl isoleucine (JA-Ile) promotes physical interaction between Arabidopsis JAZ1 and COI1 (the F-box component of SCF(COI1)) proteins, and that the JA-Ile-dependent COI1-JAZ1 interaction could be reconstituted in yeast cells (i.e. in the absence of other plant proteins).	jasmonoyl-isoleucine	28-48	RNI-like superfamily protein	Arabidopsis thaliana	146-155
18547396-4	2008	We have recently shown that jasmonoyl isoleucine (JA-Ile) promotes physical interaction between Arabidopsis JAZ1 and COI1 (the F-box component of SCF(COI1)) proteins, and that the JA-Ile-dependent COI1-JAZ1 interaction could be reconstituted in yeast cells (i.e. in the absence of other plant proteins).	jasmonoyl-isoleucine	28-48	RNI-like superfamily protein	Arabidopsis thaliana	150-154
18547396-4	2008	We have recently shown that jasmonoyl isoleucine (JA-Ile) promotes physical interaction between Arabidopsis JAZ1 and COI1 (the F-box component of SCF(COI1)) proteins, and that the JA-Ile-dependent COI1-JAZ1 interaction could be reconstituted in yeast cells (i.e. in the absence of other plant proteins).	jasmonoyl-isoleucine	28-48	jasmonate-zim-domain protein 1	Arabidopsis thaliana	202-206
18458331-2	2008	An amino acid-conjugated form of JA, jasmonoyl-isoleucine (JA-Ile), stimulates binding of the F-box protein coronatine-insensitive 1 (COI1) to, and subsequent ubiquitin-dependent degradation of, jasmonate ZIM domain (JAZ) proteins that repress transcription of JA-responsive genes.	jasmonoyl-isoleucine	37-57	coronatine-insensitive 1	Solanum lycopersicum	108-132
18458331-2	2008	An amino acid-conjugated form of JA, jasmonoyl-isoleucine (JA-Ile), stimulates binding of the F-box protein coronatine-insensitive 1 (COI1) to, and subsequent ubiquitin-dependent degradation of, jasmonate ZIM domain (JAZ) proteins that repress transcription of JA-responsive genes.	jasmonoyl-isoleucine	37-57	coronatine-insensitive 1	Solanum lycopersicum	134-138
34145662-1	2021	The F-box protein CORONANTINE INSENSITIVE1 (COI1) serves as the receptor for the plant hormone jasmonoyl-isoleucine (JA-Ile).	jasmonoyl-isoleucine	95-115	RNI-like superfamily protein	Arabidopsis thaliana	44-48
34915841-9	2021	CONCLUSION: These results indicate that the PIP5K gene family may be associated with male sterility induced by HT, and the reduction of JA-ILE levels and the abnormal levels of these genes expression may be one reason for the HT-ms anthers having no dehiscence, ultimately leading to the abortion of the anthers.	jasmonoyl-isoleucine	136-142	phosphatidylinositol-5-phosphate 4-kinase type 2 gamma	Homo sapiens	44-49
34746762-3	2021	Jasmonoyl-isoleucine (JA-Ile) is the most bioactive JAs, and perception of JA-Ile by its coreceptor, the Skp1-Cullin1-F-box-type (SCF) protein ubiquitin ligase complex SCFCOI1-JAZ, in the nucleus derepresses the transcriptional repression of target genes.	jasmonoyl-isoleucine	0-20	S-phase kinase associated protein 1	Homo sapiens	105-109
34746762-3	2021	Jasmonoyl-isoleucine (JA-Ile) is the most bioactive JAs, and perception of JA-Ile by its coreceptor, the Skp1-Cullin1-F-box-type (SCF) protein ubiquitin ligase complex SCFCOI1-JAZ, in the nucleus derepresses the transcriptional repression of target genes.	jasmonoyl-isoleucine	0-20	cullin 1	Homo sapiens	110-117
34746762-3	2021	Jasmonoyl-isoleucine (JA-Ile) is the most bioactive JAs, and perception of JA-Ile by its coreceptor, the Skp1-Cullin1-F-box-type (SCF) protein ubiquitin ligase complex SCFCOI1-JAZ, in the nucleus derepresses the transcriptional repression of target genes.	jasmonoyl-isoleucine	0-20	zinc finger protein 346	Homo sapiens	176-179
34145662-1	2021	The F-box protein CORONANTINE INSENSITIVE1 (COI1) serves as the receptor for the plant hormone jasmonoyl-isoleucine (JA-Ile).	jasmonoyl-isoleucine	117-123	RNI-like superfamily protein	Arabidopsis thaliana	44-48
31527254-8	2019	In addition to affecting electrical signaling, expression of the JA pathway marker gene JAZ10 in leaves distal to wounds was enhanced in aha1-7 Consistent with this, levels of wound-response jasmonoyl-isoleucine were enhanced in the mutant, as was defense against a lepidopteran herbivore.	jasmonoyl-isoleucine	191-211	jasmonate-zim-domain protein 10	Arabidopsis thaliana	88-93
31734923-1	2020	The phytohormone (+)-7-iso-jasmonoyl-L-isoleucine (JA-Ile) causes protein-protein interactions (PPI) between F-box Protein CORONATINE INSENSITIVE 1 (COI1) and JASMONATE ZIM DOMAIN (JAZ) transcriptional repressor.	jasmonoyl-isoleucine	4-49	RNI-like superfamily protein	Arabidopsis thaliana	123-147
31734923-1	2020	The phytohormone (+)-7-iso-jasmonoyl-L-isoleucine (JA-Ile) causes protein-protein interactions (PPI) between F-box Protein CORONATINE INSENSITIVE 1 (COI1) and JASMONATE ZIM DOMAIN (JAZ) transcriptional repressor.	jasmonoyl-isoleucine	4-49	RNI-like superfamily protein	Arabidopsis thaliana	149-153
31795159-3	2019	It starts with the perception of the active JA derivative, jasmonoyl-isoleucine (JA-Ile), by the F-box protein COI1 which is part of the E3-ligase SCFCOI1.	jasmonoyl-isoleucine	59-79	RNI-like superfamily protein	Arabidopsis thaliana	111-115
33255380-0	2020	Induction of Jasmonoyl-Isoleucine (JA-Ile)-Dependent JASMONATE ZIM-DOMAIN (JAZ) Genes in NaCl-Treated Arabidopsis thaliana Roots Can Occur at Very Low JA-Ile Levels and in the Absence of the JA/JA-Ile Transporter JAT1/AtABCG16.	jasmonoyl-isoleucine	13-33	ABC-2 type transporter family protein	Arabidopsis thaliana	218-226
33255380-0	2020	Induction of Jasmonoyl-Isoleucine (JA-Ile)-Dependent JASMONATE ZIM-DOMAIN (JAZ) Genes in NaCl-Treated Arabidopsis thaliana Roots Can Occur at Very Low JA-Ile Levels and in the Absence of the JA/JA-Ile Transporter JAT1/AtABCG16.	jasmonoyl-isoleucine	35-41	ABC-2 type transporter family protein	Arabidopsis thaliana	218-226
33255380-7	2020	The mechanism that allows COI1-dependent gene expression at very low JA-Ile levels remains to be elucidated.	jasmonoyl-isoleucine	69-75	RNI-like superfamily protein	Arabidopsis thaliana	26-30
31001304-5	2019	Among these JATs, AtJAT1/AtABCG16, has a dual localization in the plasma membrane and nuclear envelop and mediates the efflux of jasmonic acid (JA) across the plasma membrane and influx of JA-Ile into the nucleus.	jasmonoyl-isoleucine	189-195	ABC-2 type transporter family protein	Arabidopsis thaliana	25-33
31136906-10	2019	The jasmonoyl-isoleucine level increased slightly after 10 h of SGR1 overexpression, and this increase became significant after 18 h. These observations suggest that jasmonate is produced through chlorophyll a degradation and affects the promotion of senescence.	jasmonoyl-isoleucine	4-24	non-yellowing 1	Arabidopsis thaliana	64-68
29125388-1	2018	Perception of the plant hormone jasmonoyl-isoleucine (JA-Ile) involves the formation of a co-receptor complex between COI1, the F-box subunit of a SCF-type E3 ubiquitin ligase, and its substrates, a group of jasmonate ZIM-domain (JAZ) transcriptional repressors.	jasmonoyl-isoleucine	32-52	RNI-like superfamily protein	Arabidopsis thaliana	118-122
30073006-8	2018	The binding of InsP with COI1 stabilizes the conformation of COI1 and promotes the binding between JA-Ile or JAZ1 and COI1.	jasmonoyl-isoleucine	99-105	RNI-like superfamily protein	Arabidopsis thaliana	25-29
30073006-8	2018	The binding of InsP with COI1 stabilizes the conformation of COI1 and promotes the binding between JA-Ile or JAZ1 and COI1.	jasmonoyl-isoleucine	99-105	RNI-like superfamily protein	Arabidopsis thaliana	61-65
30073006-8	2018	The binding of InsP with COI1 stabilizes the conformation of COI1 and promotes the binding between JA-Ile or JAZ1 and COI1.	jasmonoyl-isoleucine	99-105	RNI-like superfamily protein	Arabidopsis thaliana	61-65
29291349-1	2018	Biosynthesis of the phytohormone jasmonoyl-isoleucine (JA-Ile) requires reduction of the JA precursor 12-oxo-phytodienoic acid (OPDA) by OPDA reductase 3 (OPR3).	jasmonoyl-isoleucine	33-53	oxophytodienoate-reductase 3	Arabidopsis thaliana	155-159
29291349-1	2018	Biosynthesis of the phytohormone jasmonoyl-isoleucine (JA-Ile) requires reduction of the JA precursor 12-oxo-phytodienoic acid (OPDA) by OPDA reductase 3 (OPR3).	jasmonoyl-isoleucine	55-61	oxophytodienoate-reductase 3	Arabidopsis thaliana	155-159
29291349-6	2018	OPR2 was found to reduce 4,5-didehydro-JA to JA, explaining the accumulation of JA-Ile and activation of JA-Ile-responses in opr3-3 mutants.	jasmonoyl-isoleucine	80-86	12-oxophytodienoate reductase 2	Arabidopsis thaliana	0-4
30243225-0	2018	Structural analysis of the woodland strawberry COI1-JAZ1 co-receptor for the plant hormone jasmonoyl-isoleucine.	jasmonoyl-isoleucine	91-111	RNI-like superfamily protein	Arabidopsis thaliana	47-51
30243225-0	2018	Structural analysis of the woodland strawberry COI1-JAZ1 co-receptor for the plant hormone jasmonoyl-isoleucine.	jasmonoyl-isoleucine	91-111	jasmonate-zim-domain protein 1	Arabidopsis thaliana	52-56
30243225-4	2018	The aim of this work was to understand the molecular basis of the interaction between the F. vesca COI1 (FvCOI1) and JAZ1 (FvJAZ1) promoted by JA-Ile using a computational approach.	jasmonoyl-isoleucine	143-149	RNI-like superfamily protein	Arabidopsis thaliana	99-103
30243225-4	2018	The aim of this work was to understand the molecular basis of the interaction between the F. vesca COI1 (FvCOI1) and JAZ1 (FvJAZ1) promoted by JA-Ile using a computational approach.	jasmonoyl-isoleucine	143-149	jasmonate-zim-domain protein 1	Arabidopsis thaliana	117-121
28179150-4	2017	We show that AtJAT1/AtABCG16 controls the cytoplasmic and nuclear partition of jasmonate phytohormones by mediating both cellular efflux of jasmonic acid (JA) and nuclear influx of jasmonoyl-isoleucine (JA-Ile), and is essential for maintaining a critical nuclear JA-Ile concentration to activate JA signaling.	jasmonoyl-isoleucine	181-201	ABC-2 type transporter family protein	Arabidopsis thaliana	20-28
28184233-10	2017	In addition, detailed analysis of differentially expressed genes associated with plant hormones and endogenous phytohormone levels in wild-type and OE-At5g02890 plants indicated that abscisic acid (ABA), jasmonic acid (JA), and jasmonoyl-isoleucine (JA-Ile) biosynthesis, as well as polar auxin transport, were also affected by overexpression of At5g02890.	jasmonoyl-isoleucine	228-248	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	151-160
28137867-2	2017	Below a threshold concentration of jasmonoyl isoleucine (JA-Ile), the active form of JA, the C-terminal Jas motif of JAZ proteins binds MYC transcription factors to repress JA signaling.	jasmonoyl-isoleucine	35-55	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	136-139
28223489-3	2017	It directly controls biosynthesis of jasmonoyl-isoleucine in JA-mediated defense responses and interacts with FIN219-interacting protein 1 (FIP1) under FR light conditions.	jasmonoyl-isoleucine	37-57	FH interacting protein 1	Arabidopsis thaliana	110-138
28223489-3	2017	It directly controls biosynthesis of jasmonoyl-isoleucine in JA-mediated defense responses and interacts with FIN219-interacting protein 1 (FIP1) under FR light conditions.	jasmonoyl-isoleucine	37-57	FH interacting protein 1	Arabidopsis thaliana	140-144