PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
29720122-6	2018	The expression of DKK1 was positively correlated with that of ss-catenin (P < 0.001).	ss-catenin	62-72	dickkopf WNT signaling pathway inhibitor 1	Homo sapiens	18-22
30728831-1	2018	This study demonstrates that FGF10/FGFR2b signaling on distal epithelial progenitor cells, via ss-catenin/EP300, controls, through a comprehensive set of developmental genes, morphogenesis, and differentiation.	ss-catenin	95-105	fibroblast growth factor 10	Mus musculus	29-34
30728831-7	2018	The relationship between FGF10 and ss-catenin signaling was also analyzed through in vitro experiments using IQ1, a pharmacological inhibitor of ss-catenin/EP300 transcriptional activity.	ss-catenin	35-45	fibroblast growth factor 10	Mus musculus	25-30
30728831-13	2018	This study demonstrates that FGF10/FGFR2b signaling on distal epithelial progenitor cells via ss-catenin/EP300 controls, through a comprehensive set of developmental genes, cell adhesion, and differentiation.	ss-catenin	94-104	fibroblast growth factor 10	Mus musculus	29-34
31133633-1	2019	BACKGROUND Transcription factor 7 (TCF7) plays an essential role in Wnt signaling by interacting with ss-catenin.	ss-catenin	102-112	transcription factor 7	Homo sapiens	11-33
31133633-1	2019	BACKGROUND Transcription factor 7 (TCF7) plays an essential role in Wnt signaling by interacting with ss-catenin.	ss-catenin	102-112	transcription factor 7	Homo sapiens	35-39
31105876-11	2019	Conclusion: It is concluded that expression of mutated CDH3 is associated with activation of cSRC, stabilization of ss-catenin and a rounded morphology related to a stemness/EMT phenotype.	ss-catenin	116-126	cadherin 3	Canis lupus familiaris	55-59
29771996-3	2018	Here we show that complete lack of AnxA6 functions resulted in increased ss-catenin activation in Wnt3a-treated murine articular chondrocytes, whereas AnxA6 expressing articular chondrocytes showed decreased ss-catenin activation.	ss-catenin	73-83	annexin A6	Mus musculus	35-40
29771996-3	2018	Here we show that complete lack of AnxA6 functions resulted in increased ss-catenin activation in Wnt3a-treated murine articular chondrocytes, whereas AnxA6 expressing articular chondrocytes showed decreased ss-catenin activation.	ss-catenin	73-83	wingless-type MMTV integration site family, member 3A	Mus musculus	98-103
29771996-3	2018	Here we show that complete lack of AnxA6 functions resulted in increased ss-catenin activation in Wnt3a-treated murine articular chondrocytes, whereas AnxA6 expressing articular chondrocytes showed decreased ss-catenin activation.	ss-catenin	208-218	annexin A6	Mus musculus	35-40
29771996-3	2018	Here we show that complete lack of AnxA6 functions resulted in increased ss-catenin activation in Wnt3a-treated murine articular chondrocytes, whereas AnxA6 expressing articular chondrocytes showed decreased ss-catenin activation.	ss-catenin	208-218	annexin A6	Mus musculus	151-156
30138931-14	2018	CONCLUSION: These data suggested that sh-March8 reduced viability and induced apoptosis of the MKN-45 and AGS cells through the PI3K and ss-catenin stat3 signaling pathways.	ss-catenin	137-147	membrane associated ring-CH-type finger 8	Homo sapiens	41-47
28834900-13	2017	ss-catenin immunostain showed reduced membranous expression in the SCC component, as compared to HCC.	ss-catenin	0-10	serpin family B member 3	Homo sapiens	67-70
28323888-0	2017	LZTS2 and PTEN collaboratively regulate ss-catenin in prostatic tumorigenesis.	ss-catenin	40-50	leucine zipper, putative tumor suppressor 2	Mus musculus	0-5
28323888-0	2017	LZTS2 and PTEN collaboratively regulate ss-catenin in prostatic tumorigenesis.	ss-catenin	40-50	phosphatase and tensin homolog	Mus musculus	10-14
28323888-6	2017	Co-expression of PTEN and LZTS2 in prostate cancer cells shows stronger repressive effect on ss-catenin mediated transcription.	ss-catenin	93-103	phosphatase and tensin homolog	Mus musculus	17-21
28323888-6	2017	Co-expression of PTEN and LZTS2 in prostate cancer cells shows stronger repressive effect on ss-catenin mediated transcription.	ss-catenin	93-103	leucine zipper, putative tumor suppressor 2	Mus musculus	26-31
25149534-10	2014	In summary, BCL9-2 induces ER positive breast cancers in vivo, regulates ER expression by a novel ss-catenin independent mechanism in breast cancer cells, and might predict the therapy response to tamoxifen treatment.	ss-catenin	98-108	BCL9 like	Homo sapiens	12-18
25364765-8	2014	BCL2L2, ss-catenin, BIM, CADM1, EZH2, FGFR1, NRAS, PTEN, TP53, and TWIST1 are representative miR-214 targets.	ss-catenin	8-18	microRNA 214	Homo sapiens	93-100
24115331-0	2014	Pax6 mediates ss-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells.	ss-catenin	14-24	paired box 6	Mus musculus	0-4
24115331-8	2014	At the molecular level, the expression of the transcription factor Pax6 is dramatically diminished in the cortical radial glia and the sphere-forming neural stem cells of ss-catenin-deficient mutants.	ss-catenin	171-181	paired box 6	Mus musculus	67-71
24115331-10	2014	The forced expression of Pax6 through lentiviral transduction partially rescues the defective proliferation and neurogenesis by ss-catenin-deficient neural stem cells.	ss-catenin	128-138	paired box 6	Mus musculus	25-29
24115331-11	2014	Thus, Pax6 is a novel downstream target of the Wnt/ss-catenin pathway, and ss-catenin/Pax6 signaling plays critical roles in self-renewal and neurogenesis of radial glia/neural stem cells during neocortical development.	ss-catenin	51-61	paired box 6	Mus musculus	6-10
23129487-1	2012	Elevated levels of nuclear beta-catenin are associated with higher rates of survival in patients with melanoma, raising questions as to how ss-catenin is regulated in this context.	ss-catenin	140-150	catenin beta 1	Homo sapiens	27-39
22968441-10	2013	Downregulation of SH3GL2 interactor USP9X and activated ss-catenin was also evident in the SH3GL2-transfected cells.	ss-catenin	56-66	SH3-domain GRB2-like 2	Mus musculus	18-24
22968441-10	2013	Downregulation of SH3GL2 interactor USP9X and activated ss-catenin was also evident in the SH3GL2-transfected cells.	ss-catenin	56-66	SH3-domain GRB2-like 2	Mus musculus	91-97
24276407-8	2014	Using immunohistochemistry, we confirmed that high ALDH3A1 expression is associated with nuclear staining for ss-catenin and strong homogeneous staining for glutamine synthetase, two classical Wnt/ss-catenin pathway activation markers.	ss-catenin	110-120	aldehyde dehydrogenase 3 family member A1	Homo sapiens	51-58
21928230-10	2012	ss-Catenin colocalized with LEF-1 in the nuclei of podocytes of animals.	ss-catenin	0-10	lymphoid enhancer binding factor 1	Homo sapiens	28-33
22198215-7	2012	ss-catenin/TCF signaling activity was significantly reduced by 5-ASA treatment possibly through a reduction in ss-catenin levels.	ss-catenin	0-10	hepatocyte nuclear factor 4 alpha	Homo sapiens	11-14
22198215-7	2012	ss-catenin/TCF signaling activity was significantly reduced by 5-ASA treatment possibly through a reduction in ss-catenin levels.	ss-catenin	111-121	hepatocyte nuclear factor 4 alpha	Homo sapiens	11-14
22298904-11	2012	Increased ss-catenin activation was demonstrated by nuclear localization of ss-catenin staining in ank/ank chondrocytes.	ss-catenin	10-20	progressive ankylosis	Mus musculus	99-102
22298904-11	2012	Increased ss-catenin activation was demonstrated by nuclear localization of ss-catenin staining in ank/ank chondrocytes.	ss-catenin	10-20	progressive ankylosis	Mus musculus	103-106
22298904-11	2012	Increased ss-catenin activation was demonstrated by nuclear localization of ss-catenin staining in ank/ank chondrocytes.	ss-catenin	76-86	progressive ankylosis	Mus musculus	99-102
22298904-11	2012	Increased ss-catenin activation was demonstrated by nuclear localization of ss-catenin staining in ank/ank chondrocytes.	ss-catenin	76-86	progressive ankylosis	Mus musculus	103-106
22844492-2	2012	PTP1B dephosphorylates ss-catenin in N-cadherin complexes ensuring cell-cell adhesion.	ss-catenin	23-33	protein tyrosine phosphatase, non-receptor type 1	Mus musculus	0-5
22844492-2	2012	PTP1B dephosphorylates ss-catenin in N-cadherin complexes ensuring cell-cell adhesion.	ss-catenin	23-33	cadherin 2	Mus musculus	37-47
22844492-7	2012	Notably, levels of ss-catenin-Tyr-654 phosphorylation increased ~5-fold in the hippocampus of adult PTP1B(-/-) (KO) mice compared to wild type (WT) mice and this was accompanied by a reduction in the amount of ss-catenin associated with N-cadherin.	ss-catenin	19-29	protein tyrosine phosphatase, non-receptor type 1	Mus musculus	100-105
22844492-7	2012	Notably, levels of ss-catenin-Tyr-654 phosphorylation increased ~5-fold in the hippocampus of adult PTP1B(-/-) (KO) mice compared to wild type (WT) mice and this was accompanied by a reduction in the amount of ss-catenin associated with N-cadherin.	ss-catenin	19-29	cadherin 2	Mus musculus	237-247
22844492-10	2012	Our results implicate PTP1B in structural plasticity within the hippocampus, likely through modulation of N-cadherin function by ensuring dephosphorylation of ss-catenin on Tyr-654.	ss-catenin	159-169	protein tyrosine phosphatase, non-receptor type 1	Mus musculus	22-27
22844492-10	2012	Our results implicate PTP1B in structural plasticity within the hippocampus, likely through modulation of N-cadherin function by ensuring dephosphorylation of ss-catenin on Tyr-654.	ss-catenin	159-169	cadherin 2	Mus musculus	106-116
22024062-5	2011	Additionally, positive correlations of ss-catenin with cyclinD1 and c-myc (r=0.412, p=0.002; r=0.447, p=0.000) and of p53 with bcl-2 (r=0.332, p=0.001) were found.	ss-catenin	39-49	cyclin D1	Homo sapiens	55-63
22457761-11	2012	Furthermore, cytoplasmic ss-catenin was detected in HER2/neu-induced mouse mammary tumors.	ss-catenin	25-35	erb-b2 receptor tyrosine kinase 2	Mus musculus	52-56
22457761-11	2012	Furthermore, cytoplasmic ss-catenin was detected in HER2/neu-induced mouse mammary tumors.	ss-catenin	25-35	erb-b2 receptor tyrosine kinase 2	Mus musculus	57-60
22136118-4	2011	RESULTS: Here we show that stat3, a known oncogene and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.	ss-catenin	67-77	signal transducer and activator of transcription 3 (acute-phase response factor)	Danio rerio	27-32
22136118-4	2011	RESULTS: Here we show that stat3, a known oncogene and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.	ss-catenin	67-77	APC regulator of WNT signaling pathway	Danio rerio	117-120
22024062-5	2011	Additionally, positive correlations of ss-catenin with cyclinD1 and c-myc (r=0.412, p=0.002; r=0.447, p=0.000) and of p53 with bcl-2 (r=0.332, p=0.001) were found.	ss-catenin	39-49	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	68-73
21165564-2	2011	Here we demonstrate that overexpression of Sox4 enhances ss-catenin/TCF activity by increasing the stability of ss-catenin.	ss-catenin	57-67	SRY-box transcription factor 4	Homo sapiens	43-47
21494877-4	2011	In addition, an increase of cyclin D1 expression and a significant decrease of glycogen synthase kinase-3beta (GSK-3ss) and beta-catenin (ss-catenin) were equally observed after 24 and 48 h of EGF treatment.	ss-catenin	138-148	catenin beta 1	Homo sapiens	124-136
21165564-2	2011	Here we demonstrate that overexpression of Sox4 enhances ss-catenin/TCF activity by increasing the stability of ss-catenin.	ss-catenin	57-67	hepatocyte nuclear factor 4 alpha	Homo sapiens	68-71
21165564-4	2011	An siRNA experiment for Sox4 also demonstrated that Sox4 increases the protein levels of ss-catenin and thus activates the Wnt signaling pathway.	ss-catenin	89-99	SRY-box transcription factor 4	Homo sapiens	24-28
21165564-4	2011	An siRNA experiment for Sox4 also demonstrated that Sox4 increases the protein levels of ss-catenin and thus activates the Wnt signaling pathway.	ss-catenin	89-99	SRY-box transcription factor 4	Homo sapiens	52-56
21281469-9	2011	Confirmation of increased Wnt signaling was provided by a TCF/LEF reporter kit and by the finding of the nuclear accumulation of ss-catenin for MDA-MB-231 EpCAM but not Hs578T EpCAM cells.	ss-catenin	129-139	epithelial cell adhesion molecule	Homo sapiens	155-160
22046319-4	2011	In addition, pharmacological inhibition of Porcupine (Porcn), an upstream regulator of Wnt, by IWP1, specifically inhibited ss-catenin dependent signaling.	ss-catenin	124-134	porcupine O-acyltransferase	Homo sapiens	43-52
21069266-8	2011	Wnt5a had no effect on total ss-catenin expression levels, but regulated tyrosine phosphorylation of ss-catenin and translocation of ss-catenin from the cytoplasm to the nucleus.	ss-catenin	101-111	Wnt family member 5A	Homo sapiens	0-5
21069266-8	2011	Wnt5a had no effect on total ss-catenin expression levels, but regulated tyrosine phosphorylation of ss-catenin and translocation of ss-catenin from the cytoplasm to the nucleus.	ss-catenin	101-111	Wnt family member 5A	Homo sapiens	0-5
22046319-4	2011	In addition, pharmacological inhibition of Porcupine (Porcn), an upstream regulator of Wnt, by IWP1, specifically inhibited ss-catenin dependent signaling.	ss-catenin	124-134	porcupine O-acyltransferase	Homo sapiens	54-59
22046319-4	2011	In addition, pharmacological inhibition of Porcupine (Porcn), an upstream regulator of Wnt, by IWP1, specifically inhibited ss-catenin dependent signaling.	ss-catenin	124-134	Wnt family member 1	Homo sapiens	87-90
20429785-11	2010	Wnt5a activated the non-canonical Wnt signaling pathway by increasing PKC activity, while Wnt3a mildly activated the Wnt canonical pathway by increasing total ss-catenin content and connexin 43 and cyclin D1 gene expression.	ss-catenin	159-169	Wnt family member 3A	Homo sapiens	90-95
21799872-7	2011	Moreover, the Barx1(-/-) esophagus displays molecular and cytologic features of respiratory endoderm, phenocopying abnormalities observed in mouse embryos with activated ss-catenin.	ss-catenin	170-180	BarH-like homeobox 1	Mus musculus	14-19
30372797-11	2020	hHMSCs activated several molecules in the Wnt/beta-catenin signalling pathway, including ss-catenin and phosphorylated GSK3b, and decreased IFN-gamma-induced expression of DKK1 in hDPCs.	ss-catenin	89-99	catenin beta 1	Homo sapiens	46-58
18231602-3	2008	Strikingly, the Dermo1(Cre/+); beta-catenin(f/-) conditional Knock Out embryos largely phenocopy Pitx1(-/-)/Pitx2(-/-) double knockout embryos, suggesting that ss-catenin signaling in the mesenchyme depends mostly on the PITX family of transcription factors.	ss-catenin	160-170	twist family bHLH transcription factor 2	Homo sapiens	16-22
18231602-3	2008	Strikingly, the Dermo1(Cre/+); beta-catenin(f/-) conditional Knock Out embryos largely phenocopy Pitx1(-/-)/Pitx2(-/-) double knockout embryos, suggesting that ss-catenin signaling in the mesenchyme depends mostly on the PITX family of transcription factors.	ss-catenin	160-170	catenin beta 1	Homo sapiens	31-43
12952568-4	2003	Perturbations in the function of either protein lead to altered gene regulation through the interaction of ss-catenin with T-cell factor (Tcf)/lymphoid enhancer binding protein (Lef) transcription factors.	ss-catenin	107-117	hepatocyte nuclear factor 4 alpha	Homo sapiens	123-136
12952568-4	2003	Perturbations in the function of either protein lead to altered gene regulation through the interaction of ss-catenin with T-cell factor (Tcf)/lymphoid enhancer binding protein (Lef) transcription factors.	ss-catenin	107-117	hepatocyte nuclear factor 4 alpha	Homo sapiens	138-141
35514236-4	2022	NTDs in Lrp6-GOF mutants may be attributed to altered ss-catenin-independent noncanonical Wnt signaling.	ss-catenin	54-64	low density lipoprotein receptor-related protein 6	Mus musculus	8-12
32279067-13	2020	CONCLUSIONS Collectively, Porcupine inhibitor Wnt-C59 attenuates pressure overload-induced cardiac hypertrophic via interruption of the Wnt/ss-catenin signaling pathway, and it might be a promising drug for patients with cardiac hypertrophy.	ss-catenin	140-150	wingless-type MMTV integration site family, member 3A	Mus musculus	46-49
32279067-13	2020	CONCLUSIONS Collectively, Porcupine inhibitor Wnt-C59 attenuates pressure overload-induced cardiac hypertrophic via interruption of the Wnt/ss-catenin signaling pathway, and it might be a promising drug for patients with cardiac hypertrophy.	ss-catenin	140-150	wingless-type MMTV integration site family, member 3A	Mus musculus	136-139
31891587-1	2019	Tankyrase (TNKS) 1/2 are positive regulators of WNT signaling by controlling the activity of the ss-catenin destruction complex.	ss-catenin	97-107	tankyrase	Homo sapiens	0-20