PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
15386188-3	2004	Consistent with these observations, the protein and mRNA expression levels of inducible NO synthase (iNOS) and cyclooxygenase (COX)-2 enzymes were inhibited by 23-hydroxyursolic acid ( 2) in a concentration-dependent manner.	23-hydroxyursolic acid	160-182	nitric oxide synthase 2, inducible	Mus musculus	78-99
30551620-0	2018	23-Hydroxyursolic Acid Isolated from the Stem Bark of Cussonia bancoensis Induces Apoptosis through Fas/Caspase-8-Dependent Pathway in HL-60 Human Promyelocytic Leukemia Cells.	23-hydroxyursolic acid	0-22	caspase 8	Homo sapiens	104-113
15386188-3	2004	Consistent with these observations, the protein and mRNA expression levels of inducible NO synthase (iNOS) and cyclooxygenase (COX)-2 enzymes were inhibited by 23-hydroxyursolic acid ( 2) in a concentration-dependent manner.	23-hydroxyursolic acid	160-182	nitric oxide synthase 2, inducible	Mus musculus	101-105
15386188-3	2004	Consistent with these observations, the protein and mRNA expression levels of inducible NO synthase (iNOS) and cyclooxygenase (COX)-2 enzymes were inhibited by 23-hydroxyursolic acid ( 2) in a concentration-dependent manner.	23-hydroxyursolic acid	160-182	cytochrome c oxidase II, mitochondrial	Mus musculus	111-133
15386188-4	2004	Furthermore, 23-hydroxyursolic acid ( 2) inhibited the LPS-induced DNA binding activity of nuclear factor- kappaB (NF- kappaB), which was associated with a decrease of p65 protein levels in the nucleus.	23-hydroxyursolic acid	13-35	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	168-171
15386188-5	2004	These results suggest that the 23-hydroxyursolic acid-mediated inhibition of iNOS and COX-2 expression, via blocking NF- kappaB activation, may mechanistically responsible for the anti-inflammatory effects of Cussonia bancoensis stem bark in vitro.	23-hydroxyursolic acid	31-53	nitric oxide synthase 2, inducible	Mus musculus	77-81
15386188-5	2004	These results suggest that the 23-hydroxyursolic acid-mediated inhibition of iNOS and COX-2 expression, via blocking NF- kappaB activation, may mechanistically responsible for the anti-inflammatory effects of Cussonia bancoensis stem bark in vitro.	23-hydroxyursolic acid	31-53	cytochrome c oxidase II, mitochondrial	Mus musculus	86-91
32860922-4	2020	23-Hydroxy ursolic acid also preserved blood monocyte mitogen-activated protein kinase phosphatase-1 activity, a biomarker of monocyte health, and reduced macrophage content in the adipose tissue.	23-hydroxyursolic acid	0-23	dual specificity phosphatase 1	Homo sapiens	54-100