PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
35604136-3	2022	We show crystal and cryo-EM structures of the gastric proton pump in complex with four different P-CABs, tegoprazan, soraprazan, PF-03716556 and revaprazan, at resolutions reaching 2.8 A.	YH 1885	145-155	ATPase H+/K+ transporting subunit alpha	Homo sapiens	54-65
33075311-11	2020	However, indomethacin and revaprazan combination significantly preserved TJPs and inactivated Rho-GTPase, MLC, and ERK.	YH 1885	26-36	modulator of VRAC current 1	Homo sapiens	106-109
33075311-11	2020	However, indomethacin and revaprazan combination significantly preserved TJPs and inactivated Rho-GTPase, MLC, and ERK.	YH 1885	26-36	mitogen-activated protein kinase 1	Homo sapiens	115-118
21401892-3	2011	Since the exact relationship between HSP27 phosphorylation and biological function remains unknown in NSAID-induced gastropathy, we hypothesized that revaprazan, a novel acid pump antagonist, can secure significant cytoprotection from NSAID damages through HSP27 accentuation.	YH 1885	150-160	heat shock protein family B (small) member 1	Rattus norvegicus	37-42
21401892-3	2011	Since the exact relationship between HSP27 phosphorylation and biological function remains unknown in NSAID-induced gastropathy, we hypothesized that revaprazan, a novel acid pump antagonist, can secure significant cytoprotection from NSAID damages through HSP27 accentuation.	YH 1885	150-160	heat shock protein family B (small) member 1	Rattus norvegicus	257-262
21401892-6	2011	HSP27 siRNA abolished these cytoprotective privileges of revaprazan.	YH 1885	57-67	heat shock protein family B (small) member 1	Rattus norvegicus	0-5
33131095-10	2020	Despite the slight increases of serum miR-122 for each drug, tegoprazan and revaprazan were well tolerated considering other safety parameters including AST and ALT levels.	YH 1885	76-86	solute carrier family 17 member 5	Homo sapiens	153-156
21401892-7	2011	Indomethacin, 40 mg/kg, po, administration provoked significant levels of gastric damages accompanied with decrement in HSP27, while rats administrated with revaprazan prior to indomethacin imposed the accentuation of HSP27, of which levels were significantly correlated with the prevention of the indomethacin-induced gastric damages.	YH 1885	157-167	heat shock protein family B (small) member 1	Rattus norvegicus	218-223
21401892-8	2011	CONCLUSION: HSP27 phosphorylation with resultant decrease in HSP27 level was one of the mechanisms of indomethacin-induced cytotoxicity, of which post-translational modifications were prevented with revaprazan administration in the presence of indomethacin.	YH 1885	199-209	heat shock protein family B (small) member 1	Rattus norvegicus	12-17
21401892-8	2011	CONCLUSION: HSP27 phosphorylation with resultant decrease in HSP27 level was one of the mechanisms of indomethacin-induced cytotoxicity, of which post-translational modifications were prevented with revaprazan administration in the presence of indomethacin.	YH 1885	199-209	heat shock protein family B (small) member 1	Rattus norvegicus	61-66
20880169-8	2010	Serum gastrin levels were rapidly normalized by 100 and 150 mg/day of revaprazan on days 1 and 7, but were significantly higher in the 200 mg/day revaprazan group.	YH 1885	70-80	gastrin	Homo sapiens	6-13
20880169-8	2010	Serum gastrin levels were rapidly normalized by 100 and 150 mg/day of revaprazan on days 1 and 7, but were significantly higher in the 200 mg/day revaprazan group.	YH 1885	146-156	gastrin	Homo sapiens	6-13