PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
12421475-5	2002	Isoverbascoside 20 micromol/L strikingly suppressed cell tumorigenicity, activities of alkaline phosphatase (ALP), and lactate dehydrogenase (LDH), and caused G0/G1 arrest.	isoacteoside	0-15	alkaline phosphatase, placental	Homo sapiens	87-107
12421475-5	2002	Isoverbascoside 20 micromol/L strikingly suppressed cell tumorigenicity, activities of alkaline phosphatase (ALP), and lactate dehydrogenase (LDH), and caused G0/G1 arrest.	isoacteoside	0-15	alkaline phosphatase, placental	Homo sapiens	109-112
12421475-6	2002	The expression of G1 S checkpoint related proteins, p53, p21/WAF1, and p16/INK4, were up-regulated after MGC 803 cells were treated with isoverbascoside 20 micromol/L for 4-8 h. Contrarily, the expression of C-myc protein was suppressed after 8 h treatment.	isoacteoside	137-152	tumor protein p53	Homo sapiens	52-55
12421475-6	2002	The expression of G1 S checkpoint related proteins, p53, p21/WAF1, and p16/INK4, were up-regulated after MGC 803 cells were treated with isoverbascoside 20 micromol/L for 4-8 h. Contrarily, the expression of C-myc protein was suppressed after 8 h treatment.	isoacteoside	137-152	cyclin dependent kinase inhibitor 1A	Homo sapiens	57-60
12421475-6	2002	The expression of G1 S checkpoint related proteins, p53, p21/WAF1, and p16/INK4, were up-regulated after MGC 803 cells were treated with isoverbascoside 20 micromol/L for 4-8 h. Contrarily, the expression of C-myc protein was suppressed after 8 h treatment.	isoacteoside	137-152	cyclin dependent kinase inhibitor 1A	Homo sapiens	61-65
12421475-6	2002	The expression of G1 S checkpoint related proteins, p53, p21/WAF1, and p16/INK4, were up-regulated after MGC 803 cells were treated with isoverbascoside 20 micromol/L for 4-8 h. Contrarily, the expression of C-myc protein was suppressed after 8 h treatment.	isoacteoside	137-152	cyclin dependent kinase inhibitor 2A	Homo sapiens	71-74
12421475-6	2002	The expression of G1 S checkpoint related proteins, p53, p21/WAF1, and p16/INK4, were up-regulated after MGC 803 cells were treated with isoverbascoside 20 micromol/L for 4-8 h. Contrarily, the expression of C-myc protein was suppressed after 8 h treatment.	isoacteoside	137-152	cyclin dependent kinase inhibitor 2A	Homo sapiens	75-79
12421475-6	2002	The expression of G1 S checkpoint related proteins, p53, p21/WAF1, and p16/INK4, were up-regulated after MGC 803 cells were treated with isoverbascoside 20 micromol/L for 4-8 h. Contrarily, the expression of C-myc protein was suppressed after 8 h treatment.	isoacteoside	137-152	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	208-213
34715512-0	2021	Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade.	isoacteoside	72-87	mitogen-activated protein kinase 8	Rattus norvegicus	175-178
9525102-1	1998	Four phenylethanoids isolated from the stems of Cistanche deserticola, acteoside (1), 2"-acetylacteoside (2), isoacteoside (3) and tubuloside B (4), significantly suppressed NADPH/CCl4-induced lipid peroxidation in rat liver microsomes.	isoacteoside	110-122	C-C motif chemokine ligand 4	Rattus norvegicus	180-184
34715512-0	2021	Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade.	isoacteoside	72-87	AKT serine/threonine kinase 1	Rattus norvegicus	183-186
34715512-0	2021	Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade.	isoacteoside	72-87	mechanistic target of rapamycin kinase	Rattus norvegicus	187-191
34715512-12	2021	ISOVER decreased the phosphorylation of p38 mitogen-activated protein kinase (p38MAPK) and c-Jun N-terminal kinase (JNK) and increased that of mammalian target of rapamycin (mTOR), thereby attenuating IR.	isoacteoside	0-6	mitogen-activated protein kinase 14	Homo sapiens	40-76
34715512-12	2021	ISOVER decreased the phosphorylation of p38 mitogen-activated protein kinase (p38MAPK) and c-Jun N-terminal kinase (JNK) and increased that of mammalian target of rapamycin (mTOR), thereby attenuating IR.	isoacteoside	0-6	mitogen-activated protein kinase 14	Homo sapiens	78-85
34715512-12	2021	ISOVER decreased the phosphorylation of p38 mitogen-activated protein kinase (p38MAPK) and c-Jun N-terminal kinase (JNK) and increased that of mammalian target of rapamycin (mTOR), thereby attenuating IR.	isoacteoside	0-6	mitogen-activated protein kinase 8	Homo sapiens	91-114
34715512-12	2021	ISOVER decreased the phosphorylation of p38 mitogen-activated protein kinase (p38MAPK) and c-Jun N-terminal kinase (JNK) and increased that of mammalian target of rapamycin (mTOR), thereby attenuating IR.	isoacteoside	0-6	mitogen-activated protein kinase 8	Homo sapiens	116-119
34715512-12	2021	ISOVER decreased the phosphorylation of p38 mitogen-activated protein kinase (p38MAPK) and c-Jun N-terminal kinase (JNK) and increased that of mammalian target of rapamycin (mTOR), thereby attenuating IR.	isoacteoside	0-6	mechanistic target of rapamycin kinase	Homo sapiens	143-172
34715512-12	2021	ISOVER decreased the phosphorylation of p38 mitogen-activated protein kinase (p38MAPK) and c-Jun N-terminal kinase (JNK) and increased that of mammalian target of rapamycin (mTOR), thereby attenuating IR.	isoacteoside	0-6	mechanistic target of rapamycin kinase	Homo sapiens	174-178
32530282-10	2020	FEP results indicate that two natural compounds, cannabisin A and isoacteoside, and an HIV-1 PR inhibitor, darunavir, exhibit a large binding free energy to SARS-CoV-2 Mpro, which is larger than that of 13b, the most reliable SARS-CoV-2 Mpro inhibitor recently reported.	isoacteoside	66-78	NEWENTRY	Severe acute respiratory syndrome-related coronavirus	168-172
32530282-10	2020	FEP results indicate that two natural compounds, cannabisin A and isoacteoside, and an HIV-1 PR inhibitor, darunavir, exhibit a large binding free energy to SARS-CoV-2 Mpro, which is larger than that of 13b, the most reliable SARS-CoV-2 Mpro inhibitor recently reported.	isoacteoside	66-78	NEWENTRY	Severe acute respiratory syndrome-related coronavirus	237-241
30941982-0	2019	Suppression of in vitro and in vivo human ovarian cancer growth by isoacteoside is mediated via sub-G1 cell cycle arrest, ROS generation, and modulation of AKT/PI3K/m-TOR signalling pathway.	isoacteoside	67-79	AKT serine/threonine kinase 1	Homo sapiens	156-159
30908093-3	2020	Phenylethanoids, acteoside (5) and isoacteoside (6) showed significant inhibitory to IL-2 secretion of with respect to phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood T cells.	isoacteoside	35-47	interleukin 2	Homo sapiens	85-89
30908093-3	2020	Phenylethanoids, acteoside (5) and isoacteoside (6) showed significant inhibitory to IL-2 secretion of with respect to phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood T cells.	isoacteoside	35-47	CD28 molecule	Homo sapiens	154-158
31272310-4	2019	Moreover, acteoside and isoacteoside reduced the glutamate-induced increase of caspase-3 activity and also ameliorated the glutamate-induced Bcl-2/Bax ratio reduction in PC12 cells.	isoacteoside	24-36	caspase 3	Rattus norvegicus	79-88
31272310-4	2019	Moreover, acteoside and isoacteoside reduced the glutamate-induced increase of caspase-3 activity and also ameliorated the glutamate-induced Bcl-2/Bax ratio reduction in PC12 cells.	isoacteoside	24-36	BCL2, apoptosis regulator	Rattus norvegicus	141-146
31272310-4	2019	Moreover, acteoside and isoacteoside reduced the glutamate-induced increase of caspase-3 activity and also ameliorated the glutamate-induced Bcl-2/Bax ratio reduction in PC12 cells.	isoacteoside	24-36	BCL2 associated X, apoptosis regulator	Rattus norvegicus	147-150
31114496-10	2019	Besides, PASE and its major active constituents of phenylethanoid glycosides, including isoacteoside, plantamajoside and acteoside, were found to effectively inhibit angiotensin-converting enzyme (ACE) activation in vitro.	isoacteoside	88-100	angiotensin I converting enzyme	Rattus norvegicus	166-195
31114496-10	2019	Besides, PASE and its major active constituents of phenylethanoid glycosides, including isoacteoside, plantamajoside and acteoside, were found to effectively inhibit angiotensin-converting enzyme (ACE) activation in vitro.	isoacteoside	88-100	angiotensin I converting enzyme	Rattus norvegicus	197-200
33356909-12	2020	As a result, from more than 400,000 compounds, a total of 3 best candidate compounds (Echinacoside, Isoacteoside, K284-4402) were selected and validated for their binding to catalytic site of p110alpha and stability during Molecular Dynamics (MD) simulations.	isoacteoside	100-112	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Homo sapiens	192-201
33356909-13	2020	The binding free energy (calculated from MM-PBSA) of the selected compounds, Echinacoside, Isoacteoside, K284-4402 were -23.43 kcal/mol, -33.02 kcal/mol and -30.57 kcal/mol, respectively, which suggested these compounds bind to p110alpha with higher affinity than Alpelisib which has binding free energy -20.9 kcal/mol.	isoacteoside	91-103	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Homo sapiens	228-237
30668420-0	2019	Plant-derived verbascoside and isoverbascoside regulate Toll-like receptor 2 and 4-driven neutrophils priming and activation.	isoacteoside	31-46	toll-like receptor 2	Mus musculus	56-82
28616865-10	2017	In addition, isoacteoside inhibited LPS-induced transcriptional activity of AP-1 by reducing the levels of phosphorylated JNK1/2 and p38MAPK.	isoacteoside	13-25	mitogen-activated protein kinase 8	Mus musculus	122-128
28616865-9	2017	Furthermore, isoacteoside attenuated the LPS-induced transcriptional activity of NF-kappaB by decreasing the levels of phosphorylated IkappaB-alpha and IKK and NF-kappaB/p65 nuclear translocation.	isoacteoside	13-25	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	170-173
28616865-10	2017	In addition, isoacteoside inhibited LPS-induced transcriptional activity of AP-1 by reducing the levels of phosphorylated JNK1/2 and p38MAPK.	isoacteoside	13-25	mitogen-activated protein kinase 14	Mus musculus	133-140
28616865-0	2017	Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization.	isoacteoside	0-12	toll-like receptor 4	Mus musculus	100-120
28616865-8	2017	KEY RESULTS: Isoacteoside suppressed COX-2, iNOS, TNF-alpha, IL-6 and IL-1beta expression.	isoacteoside	13-25	cytochrome c oxidase II, mitochondrial	Mus musculus	37-42
28616865-11	2017	Isoacteoside blocked LPS-induced TLR4 dimerization, resulting in a reduction in the recruitment of MyD88 and TIR-domain-containing adapter-inducing interferon-beta (TRIF) and the phosphorylation of TGF-beta-activated kinase-1 (TAK1).	isoacteoside	0-12	toll-like receptor 4	Mus musculus	33-37
28616865-8	2017	KEY RESULTS: Isoacteoside suppressed COX-2, iNOS, TNF-alpha, IL-6 and IL-1beta expression.	isoacteoside	13-25	nitric oxide synthase 2, inducible	Mus musculus	44-48
28616865-11	2017	Isoacteoside blocked LPS-induced TLR4 dimerization, resulting in a reduction in the recruitment of MyD88 and TIR-domain-containing adapter-inducing interferon-beta (TRIF) and the phosphorylation of TGF-beta-activated kinase-1 (TAK1).	isoacteoside	0-12	myeloid differentiation primary response gene 88	Mus musculus	99-104
28616865-8	2017	KEY RESULTS: Isoacteoside suppressed COX-2, iNOS, TNF-alpha, IL-6 and IL-1beta expression.	isoacteoside	13-25	tumor necrosis factor	Mus musculus	50-59
28616865-11	2017	Isoacteoside blocked LPS-induced TLR4 dimerization, resulting in a reduction in the recruitment of MyD88 and TIR-domain-containing adapter-inducing interferon-beta (TRIF) and the phosphorylation of TGF-beta-activated kinase-1 (TAK1).	isoacteoside	0-12	toll-like receptor adaptor molecule 1	Mus musculus	165-169
28616865-8	2017	KEY RESULTS: Isoacteoside suppressed COX-2, iNOS, TNF-alpha, IL-6 and IL-1beta expression.	isoacteoside	13-25	interleukin 6	Mus musculus	61-65
28616865-8	2017	KEY RESULTS: Isoacteoside suppressed COX-2, iNOS, TNF-alpha, IL-6 and IL-1beta expression.	isoacteoside	13-25	interleukin 1 beta	Mus musculus	70-78
28616865-11	2017	Isoacteoside blocked LPS-induced TLR4 dimerization, resulting in a reduction in the recruitment of MyD88 and TIR-domain-containing adapter-inducing interferon-beta (TRIF) and the phosphorylation of TGF-beta-activated kinase-1 (TAK1).	isoacteoside	0-12	mitogen-activated protein kinase kinase kinase 7	Mus musculus	198-225
28616865-11	2017	Isoacteoside blocked LPS-induced TLR4 dimerization, resulting in a reduction in the recruitment of MyD88 and TIR-domain-containing adapter-inducing interferon-beta (TRIF) and the phosphorylation of TGF-beta-activated kinase-1 (TAK1).	isoacteoside	0-12	mitogen-activated protein kinase kinase kinase 7	Mus musculus	227-231
28616865-9	2017	Furthermore, isoacteoside attenuated the LPS-induced transcriptional activity of NF-kappaB by decreasing the levels of phosphorylated IkappaB-alpha and IKK and NF-kappaB/p65 nuclear translocation.	isoacteoside	13-25	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	81-90
28616865-13	2017	CONCLUSIONS AND IMPLICATIONS: Isoacteoside blocked TLR4 dimerization, which activates the MyD88-TAK1-NF-kappaB/MAPK signalling cascades and TRIF pathway.	isoacteoside	30-42	toll-like receptor 4	Mus musculus	51-55
28616865-9	2017	Furthermore, isoacteoside attenuated the LPS-induced transcriptional activity of NF-kappaB by decreasing the levels of phosphorylated IkappaB-alpha and IKK and NF-kappaB/p65 nuclear translocation.	isoacteoside	13-25	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	134-147
28616865-13	2017	CONCLUSIONS AND IMPLICATIONS: Isoacteoside blocked TLR4 dimerization, which activates the MyD88-TAK1-NF-kappaB/MAPK signalling cascades and TRIF pathway.	isoacteoside	30-42	myeloid differentiation primary response gene 88	Mus musculus	90-95
28616865-9	2017	Furthermore, isoacteoside attenuated the LPS-induced transcriptional activity of NF-kappaB by decreasing the levels of phosphorylated IkappaB-alpha and IKK and NF-kappaB/p65 nuclear translocation.	isoacteoside	13-25	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	160-169
28616865-13	2017	CONCLUSIONS AND IMPLICATIONS: Isoacteoside blocked TLR4 dimerization, which activates the MyD88-TAK1-NF-kappaB/MAPK signalling cascades and TRIF pathway.	isoacteoside	30-42	mitogen-activated protein kinase kinase kinase 7	Mus musculus	96-100
28616865-13	2017	CONCLUSIONS AND IMPLICATIONS: Isoacteoside blocked TLR4 dimerization, which activates the MyD88-TAK1-NF-kappaB/MAPK signalling cascades and TRIF pathway.	isoacteoside	30-42	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	101-110
28616865-13	2017	CONCLUSIONS AND IMPLICATIONS: Isoacteoside blocked TLR4 dimerization, which activates the MyD88-TAK1-NF-kappaB/MAPK signalling cascades and TRIF pathway.	isoacteoside	30-42	toll-like receptor adaptor molecule 1	Mus musculus	140-144
25975581-4	2015	The anti-inflammatory effect of isoacteoside was investigated in HMC-1 cells by studying the following markers: phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI)-induced interleukin (IL)-1beta, IL-6, IL-8, and tumor necrosis factor alpha (TNF-alpha) secretion and mRNA expression by ELISA and RT-PCR, respectively.	isoacteoside	32-44	interleukin 6	Homo sapiens	213-217
25975581-4	2015	The anti-inflammatory effect of isoacteoside was investigated in HMC-1 cells by studying the following markers: phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI)-induced interleukin (IL)-1beta, IL-6, IL-8, and tumor necrosis factor alpha (TNF-alpha) secretion and mRNA expression by ELISA and RT-PCR, respectively.	isoacteoside	32-44	C-X-C motif chemokine ligand 8	Homo sapiens	219-223
25975581-4	2015	The anti-inflammatory effect of isoacteoside was investigated in HMC-1 cells by studying the following markers: phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI)-induced interleukin (IL)-1beta, IL-6, IL-8, and tumor necrosis factor alpha (TNF-alpha) secretion and mRNA expression by ELISA and RT-PCR, respectively.	isoacteoside	32-44	tumor necrosis factor	Homo sapiens	229-256
25975581-4	2015	The anti-inflammatory effect of isoacteoside was investigated in HMC-1 cells by studying the following markers: phorbol 12-myristate 13-acetate and calcium ionophore A23187 (PMACI)-induced interleukin (IL)-1beta, IL-6, IL-8, and tumor necrosis factor alpha (TNF-alpha) secretion and mRNA expression by ELISA and RT-PCR, respectively.	isoacteoside	32-44	tumor necrosis factor	Homo sapiens	258-267
25975581-6	2015	Isoacteoside significantly suppressed the production and mRNA expression of proinflammatory cytokines including IL-1beta, IL-6, IL-8 and TNF-alpha in PMACI-stimulated HMC-1 cells without cytotoxicity.	isoacteoside	0-12	interleukin 1 beta	Homo sapiens	112-120
25975581-6	2015	Isoacteoside significantly suppressed the production and mRNA expression of proinflammatory cytokines including IL-1beta, IL-6, IL-8 and TNF-alpha in PMACI-stimulated HMC-1 cells without cytotoxicity.	isoacteoside	0-12	interleukin 6	Homo sapiens	122-126
25975581-6	2015	Isoacteoside significantly suppressed the production and mRNA expression of proinflammatory cytokines including IL-1beta, IL-6, IL-8 and TNF-alpha in PMACI-stimulated HMC-1 cells without cytotoxicity.	isoacteoside	0-12	C-X-C motif chemokine ligand 8	Homo sapiens	128-132
25975581-6	2015	Isoacteoside significantly suppressed the production and mRNA expression of proinflammatory cytokines including IL-1beta, IL-6, IL-8 and TNF-alpha in PMACI-stimulated HMC-1 cells without cytotoxicity.	isoacteoside	0-12	tumor necrosis factor	Homo sapiens	137-146
25975581-7	2015	It was found that anti-inflammatory effects of isoacteoside are mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B pathways.	isoacteoside	47-59	caspase 1	Homo sapiens	86-95
25975581-7	2015	It was found that anti-inflammatory effects of isoacteoside are mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B pathways.	isoacteoside	47-59	mitogen-activated protein kinase 14	Homo sapiens	157-160
19807155-3	2009	Here, we found that acteoside, isoacteoside, and 6-O-acetylacteoside inhibited IL-1beta-activated expression of intercellular CAM-1 (ICAM-1) and vascular CAM-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs); the inhibitory potency was as follows: 6-O-acetylacteoside > acteoside > isoacteoside.	isoacteoside	300-312	interleukin 1 beta	Homo sapiens	79-87
19807155-3	2009	Here, we found that acteoside, isoacteoside, and 6-O-acetylacteoside inhibited IL-1beta-activated expression of intercellular CAM-1 (ICAM-1) and vascular CAM-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs); the inhibitory potency was as follows: 6-O-acetylacteoside > acteoside > isoacteoside.	isoacteoside	300-312	intercellular adhesion molecule 1	Homo sapiens	133-139
24288293-4	2013	In the rat lens aldose reductase assay, acteoside, isoacteoside, and poliumoside exhibited greater inhibitory effects on rat lens aldose reductase with IC50 values of 0.83, 0.83, and 0.85 microM, respectively, than those of the positive controls, 3,3-tetramethyleneglutaric acid (IC50=4.03 microM) and quercetin (IC50=7.2 microM).	isoacteoside	51-63	aldo-keto reductase family 1 member B1	Rattus norvegicus	16-32
24288293-4	2013	In the rat lens aldose reductase assay, acteoside, isoacteoside, and poliumoside exhibited greater inhibitory effects on rat lens aldose reductase with IC50 values of 0.83, 0.83, and 0.85 microM, respectively, than those of the positive controls, 3,3-tetramethyleneglutaric acid (IC50=4.03 microM) and quercetin (IC50=7.2 microM).	isoacteoside	51-63	aldo-keto reductase family 1 member B1	Rattus norvegicus	130-146
19807155-3	2009	Here, we found that acteoside, isoacteoside, and 6-O-acetylacteoside inhibited IL-1beta-activated expression of intercellular CAM-1 (ICAM-1) and vascular CAM-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs); the inhibitory potency was as follows: 6-O-acetylacteoside > acteoside > isoacteoside.	isoacteoside	31-43	interleukin 1 beta	Homo sapiens	79-87
19807155-3	2009	Here, we found that acteoside, isoacteoside, and 6-O-acetylacteoside inhibited IL-1beta-activated expression of intercellular CAM-1 (ICAM-1) and vascular CAM-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs); the inhibitory potency was as follows: 6-O-acetylacteoside > acteoside > isoacteoside.	isoacteoside	31-43	intercellular adhesion molecule 1	Homo sapiens	133-139
19807155-3	2009	Here, we found that acteoside, isoacteoside, and 6-O-acetylacteoside inhibited IL-1beta-activated expression of intercellular CAM-1 (ICAM-1) and vascular CAM-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs); the inhibitory potency was as follows: 6-O-acetylacteoside > acteoside > isoacteoside.	isoacteoside	31-43	vascular cell adhesion molecule 1	Homo sapiens	161-167
19894519-3	2009	RESULT: Both acteoside and isoacteoside could increase the expression of CD11c, CD86, MHC II and CD80 on DCs surface.	isoacteoside	27-39	integrin alpha X	Mus musculus	73-78
19894519-3	2009	RESULT: Both acteoside and isoacteoside could increase the expression of CD11c, CD86, MHC II and CD80 on DCs surface.	isoacteoside	27-39	CD86 antigen	Mus musculus	80-84
19894519-3	2009	RESULT: Both acteoside and isoacteoside could increase the expression of CD11c, CD86, MHC II and CD80 on DCs surface.	isoacteoside	27-39	histocompatibility-2, MHC	Mus musculus	86-92
19894519-3	2009	RESULT: Both acteoside and isoacteoside could increase the expression of CD11c, CD86, MHC II and CD80 on DCs surface.	isoacteoside	27-39	CD80 antigen	Mus musculus	97-101