PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 33157220-5 2021 Results presented here showed that these steroidal compounds are able to decrease rate of hydroxylation of essential CYP17A1 substrate - progesterone, while some compounds completely inhibited enzyme activity. substrate - 125-136 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 117-124