PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 33511099-13 2020 The consistent kinetic and structural results expose adipoyl phosphonate as a valuable pharmacological tool for specific in vivo inhibition of the DHTKD1-encoded OADH, a new member of mammalian family of 2-oxo acid dehydrogenases, up-regulated in some cancers and associated with diabetes and obesity. adipoyl phosphonate 53-72 dehydrogenase E1 and transketolase domain containing 1 Homo sapiens 147-153