PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2068097-3	1991	The hexanucleotide originally identified is necessary for DNA binding by c-MYC, but not sufficient; the c-MYC target site is a 12-nucleotide-long palindrome.	12-nucleotide	127-140	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	73-78
2068097-3	1991	The hexanucleotide originally identified is necessary for DNA binding by c-MYC, but not sufficient; the c-MYC target site is a 12-nucleotide-long palindrome.	12-nucleotide	127-140	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	104-109
34529889-7	2021	Additionally, a 12-nucleotide insertion was found in GPCR gene of LSDV strains from 2019 outbreaks in India and Bangladesh.	12-nucleotide	16-29	G protein-coupled receptor 166 pseudogene	Homo sapiens	53-57
35176063-5	2022	The N.7 lineage includes several individuals with a 12-nucleotide deletion that removes four amino acids of the ORF7a.	12-nucleotide	52-65	ORF7a protein	Severe acute respiratory syndrome coronavirus 2	112-117
17526645-3	2007	To reveal the mechanisms of KH domain-D/RNA recognition and its functional importance, we have determined the crystal structures of PCBP2 KH1 domain in complex with a 12-nucleotide DNA corresponding to two repeats of the human C-rich strand telomeric DNA and its RNA equivalent.	12-nucleotide	167-180	poly(rC) binding protein 2	Homo sapiens	132-137
26957543-8	2016	We attribute distinct Fpr3 expression in these strains to the presence or absence of a 12-nucleotide in-frame deletion (Fpr3Delta424-435).	12-nucleotide	87-100	formyl peptide receptor 3	Mus musculus	22-26
24376613-2	2013	By additional sequencing in SLC6A3, we identified an intronic 12-nucleotide poly(A) insertion ("PolyA(22)") before the terminal exon that was associated with seizure, "glazing over" behaviors, and episodic biting behaviors in a sample of 138 Malinois.	12-nucleotide	62-75	solute carrier family 6 member 3	Canis lupus familiaris	28-34
19728989-0	2010	Identification of a novel 12-nucleotide insertion polymorphism in the promoter region of ADRA2B: full linkage with the 9-nucleotide deletion in the coding region and influence on transcriptional activity.	12-nucleotide	26-39	adrenoceptor alpha 2B	Homo sapiens	89-95
19728989-4	2010	Transfection of various cell lines with luciferase constructs containing a 5.5 kb fragment of the ADRA2B promoter region indicated that the 12-nucleotide insertion at -4825 resulted in a large reduction of transcriptional activity.	12-nucleotide	140-153	adrenoceptor alpha 2B	Homo sapiens	98-104
19728989-5	2010	Electrophoretic mobility shift assays with oligonucleotide probes corresponding to the two ADRA2B alleles demonstrated that the region where the -4825 del/ins variation occurs binds nuclear proteins and that the 12-nucleotide insertion affects the pattern of bound transcription factors.	12-nucleotide	212-225	adrenoceptor alpha 2B	Homo sapiens	91-97
19505508-4	2009	With respect to syncytin-1, MSRVenv sequences have a 12-nucleotide insertion in the trans-membrane moiety.	12-nucleotide	53-66	endogenous retrovirus group W member 1, envelope	Homo sapiens	16-26
19050726-4	2009	In patients from an unrelated family a 12-nucleotide deletion (c.2997_3008del) in FLNC resulting in a predicted in-frame four-residue deletion (p.Val930_Thr933del) in the seventh repeat of filamin C was identified.	12-nucleotide	39-52	filamin C	Homo sapiens	82-86
19050726-4	2009	In patients from an unrelated family a 12-nucleotide deletion (c.2997_3008del) in FLNC resulting in a predicted in-frame four-residue deletion (p.Val930_Thr933del) in the seventh repeat of filamin C was identified.	12-nucleotide	39-52	filamin C	Homo sapiens	189-198
33501730-3	2021	Here, we report the emergence of a 12-nucleotide deletion in ORF7a, resulting in a 4-amino-acid in-frame deletion.	12-nucleotide	35-48	ORF7a protein	Severe acute respiratory syndrome coronavirus 2	61-66
20651814-1	2010	OBJECTIVE: The present study aimed to estimate the association between susceptibility to migraine and the 12-nucleotide insertion/deletion (indel) polymorphism in promoter region of alpha(2B)-adrenergic receptor gene (ADRA2B).	12-nucleotide	106-119	adrenoceptor alpha 2B	Homo sapiens	218-224
17526645-3	2007	To reveal the mechanisms of KH domain-D/RNA recognition and its functional importance, we have determined the crystal structures of PCBP2 KH1 domain in complex with a 12-nucleotide DNA corresponding to two repeats of the human C-rich strand telomeric DNA and its RNA equivalent.	12-nucleotide	167-180	potassium voltage-gated channel modifier subfamily F member 1	Homo sapiens	138-141
10217141-2	1999	The crystal structure has now been determined at 2.6 A resolution of the complex formed between two tandemly arranged RNA-binding domains of the Sxl protein and a 12-nucleotide, single-stranded RNA derived from the tra polypyrimidine tract.	12-nucleotide	163-176	Sex lethal	Drosophila melanogaster	145-148
16540463-11	2006	Addition of a 12-nucleotide chain to the cap structure increased affinity at high ionic strength for both eIF4E (24-fold) and eIF4E(P) (7-fold), primarily due to a decrease in k(off).	12-nucleotide	14-27	eukaryotic translation initiation factor 4E	Homo sapiens	106-111
16540463-11	2006	Addition of a 12-nucleotide chain to the cap structure increased affinity at high ionic strength for both eIF4E (24-fold) and eIF4E(P) (7-fold), primarily due to a decrease in k(off).	12-nucleotide	14-27	eukaryotic translation initiation factor 4E	Homo sapiens	126-134
10323862-2	1999	The crystal structure of UP1, the amino-terminal domain of human hnRNP A1 containing two RNA-recognition motifs (RRMs), bound to a 12-nucleotide single-stranded telomeric DNA has been determined at 2.1 A resolution.	12-nucleotide	131-144	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	25-28
10323862-2	1999	The crystal structure of UP1, the amino-terminal domain of human hnRNP A1 containing two RNA-recognition motifs (RRMs), bound to a 12-nucleotide single-stranded telomeric DNA has been determined at 2.1 A resolution.	12-nucleotide	131-144	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	65-73
11785296-4	2001	A new 12-nucleotide duplication g.71741ins12nt found in intron 20 of the BRCA1 gene was described.	12-nucleotide	6-19	BRCA1 DNA repair associated	Homo sapiens	73-78
10217141-2	1999	The crystal structure has now been determined at 2.6 A resolution of the complex formed between two tandemly arranged RNA-binding domains of the Sxl protein and a 12-nucleotide, single-stranded RNA derived from the tra polypyrimidine tract.	12-nucleotide	163-176	transformer	Drosophila melanogaster	186-189
7730337-6	1995	Between bp +11 and +40 lies a 12-nucleotide sequence (CCCCGCCCACCC) containing overlapping binding sites for AP2 (CCGCCCACCC) and SP1 (CCCGCC); this region may be important for conferring the basal transcriptional activity of the Ng/RC3 gene.	12-nucleotide	30-43	transcription factor AP-2 alpha	Homo sapiens	109-112
9409529-0	1997	Instability of the 12-nucleotide repeat in c-myb gene of bovine T-lymphoma cells.	12-nucleotide	19-32	MYB proto-oncogene, transcription factor	Bos taurus	43-48
9409529-1	1997	Insertion of a 12-nucleotide repeat in c-myb gene exon 9 was observed in about 15% of sporadic bovine T-lymphomas.	12-nucleotide	15-28	MYB proto-oncogene, transcription factor	Bos taurus	39-44
10079186-4	1999	In addition, a previously unidentified mouse RXRbeta isoform containing a 12-nucleotide insertion in exon 7 was detected.	12-nucleotide	74-87	retinoid X receptor beta	Mus musculus	45-52
9532348-2	1998	Catalano et al reported an association between delusional disorder and the number of a 12-nucleotide (bp) repeat sequence in the first exon of dopamine D4 receptor gene (DRD4), which indicated a possible role of this polymorphism in the pathogenesis of psychotic disorders.	12-nucleotide	87-100	dopamine receptor D4	Homo sapiens	143-163
9532348-2	1998	Catalano et al reported an association between delusional disorder and the number of a 12-nucleotide (bp) repeat sequence in the first exon of dopamine D4 receptor gene (DRD4), which indicated a possible role of this polymorphism in the pathogenesis of psychotic disorders.	12-nucleotide	87-100	dopamine receptor D4	Homo sapiens	170-174
9190893-7	1997	These data suggest that insertion of the 12-nucleotide repeat in codon 359 may result in c-Myb proteins having high- and low-transcription-activating activity.	12-nucleotide	41-54	MYB proto-oncogene, transcription factor	Bos taurus	89-94
7730337-6	1995	Between bp +11 and +40 lies a 12-nucleotide sequence (CCCCGCCCACCC) containing overlapping binding sites for AP2 (CCGCCCACCC) and SP1 (CCCGCC); this region may be important for conferring the basal transcriptional activity of the Ng/RC3 gene.	12-nucleotide	30-43	neurogranin	Homo sapiens	233-236
7982968-9	1994	Furthermore, complementation analysis of the thi6 null strain with the modified THI6 DNAs by a 12-nucleotide linker insertion suggested that a region from amino acids 138 to 187 and that from amino acids 370 to 453 are involved in functional domains of TMP-PPase and Th-kinase, respectively, whereas the COOH-terminal region is necessary for both enzyme activities.	12-nucleotide	95-108	bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase	Saccharomyces cerevisiae S288C	45-49
7982968-9	1994	Furthermore, complementation analysis of the thi6 null strain with the modified THI6 DNAs by a 12-nucleotide linker insertion suggested that a region from amino acids 138 to 187 and that from amino acids 370 to 453 are involved in functional domains of TMP-PPase and Th-kinase, respectively, whereas the COOH-terminal region is necessary for both enzyme activities.	12-nucleotide	95-108	bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase	Saccharomyces cerevisiae S288C	80-84
8382345-4	1993	The motif GGGTGA arranged as a direct repeat with a spacing of six nucleotides or as a palindrome without spacing, or as an inverted palindrome with a 12-nucleotide spacing, confers vitamin D inducibility mediated by VDR alone.	12-nucleotide	151-164	vitamin D receptor	Homo sapiens	217-220
7933107-10	1994	However, when p54 genes from viral clones generated by cell culture passage and coding for p54 proteins with different electrophoretic mobility were sequenced, they showed changes in the number of copies of a 12-nucleotide sequence repeat.	12-nucleotide	209-222	interferon induced protein with tetratricopeptide repeats 2	Homo sapiens	14-17
7933107-10	1994	However, when p54 genes from viral clones generated by cell culture passage and coding for p54 proteins with different electrophoretic mobility were sequenced, they showed changes in the number of copies of a 12-nucleotide sequence repeat.	12-nucleotide	209-222	interferon induced protein with tetratricopeptide repeats 2	Homo sapiens	91-94
8088751-0	1994	Genetic polymorphism of apolipoprotein A-IV in the chimpanzee: common deletion of a conserved 12-nucleotide tandem repeat.	12-nucleotide	94-107	LOC107972172	Pan troglodytes	24-43