PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
17595105-0	2007	Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium.	Diterpenes, Clerodane	92-101	taste 2 receptor member 46	Homo sapiens	48-56
22802135-0	2012	A chemical proteomics approach reveals Hsp27 as a target for proapoptotic clerodane diterpenes.	Diterpenes, Clerodane	74-94	heat shock protein family B (small) member 1	Homo sapiens	39-44
17917302-0	2007	Clerodane diterpenoids and flavonoids with NGF-potentiating activity from the aerial parts of Baccharis gaudichaudiana.	Diterpenes, Clerodane	0-9	nerve growth factor	Rattus norvegicus	43-46
17595105-5	2007	By further investigation of its agonist pattern, we characterized hTAS2R46 as a bitter receptor broadly tuned to sesquiterpene lactones and to clerodane and labdane diterpenoids as well as to the unrelated bitter substances strychnine and denatonium.	Diterpenes, Clerodane	143-152	taste 2 receptor member 46	Homo sapiens	66-74
11142848-2	2000	The structures were determined by spectroscopic methods as clerodane diterpenes unsaturated at C-3, C-13(16) and C-14.	Diterpenes, Clerodane	59-68	complement C3	Homo sapiens	95-98
28934646-0	2017	Clerodane diterpenoids from Scutellaria formosana with inhibitory effects on NO production and interactions with iNOS protein.	Diterpenes, Clerodane	0-9	nitric oxide synthase 2, inducible	Mus musculus	113-117
27412850-0	2017	In vitro metabolism of the anti-inflammatory clerodane diterpenoid polyandric acid A and its hydrolysis product by human liver microsomes and recombinant cytochrome P450 and UDP-glucuronosyltransferase enzymes.	Diterpenes, Clerodane	45-54	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	154-169
27412850-0	2017	In vitro metabolism of the anti-inflammatory clerodane diterpenoid polyandric acid A and its hydrolysis product by human liver microsomes and recombinant cytochrome P450 and UDP-glucuronosyltransferase enzymes.	Diterpenes, Clerodane	45-54	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	174-201
24033131-2	2013	Compounds 1 and 2 are the first examples of clerodane diterpenoids with an oxygen bridge between C-2 and C-19, and compounds 5-7 are three new diterpenoid artifacts presumably formed during the extraction process.	Diterpenes, Clerodane	44-53	complement C2	Homo sapiens	97-100
8917367-3	1996	The methanol extract of a Brazilian propolis was fractionated by HPLC, and a tumoricidal substance was isolated and characterized as a new clerodane diterpenoid (PMS-1) with a molecular formula of C20H32O3 (MW: 320).	Diterpenes, Clerodane	139-148	PMS1 homolog 1, mismatch repair system component	Mus musculus	162-167
33352228-12	2021	Collectively, our study reveals that new clerodane-type diterpenoid CA suppresses LPS-induced inflammation by promoting TRAF6 degradation, suggesting that CA as the potential therapeutic candidate for the treatment of inflammation associated diseases.	Diterpenes, Clerodane	41-50	TNF receptor-associated factor 6	Mus musculus	120-125
32157723-0	2020	Fragmentation study of clerodane diterpenes from Casearia species by tandem mass spectrometry (QToF and Ion Trap).	Diterpenes, Clerodane	23-32	TRAP	Homo sapiens	108-112
30691220-4	2019	This study aimed to validate the DPP-4 inhibitory activity of clerodane diterpene 16-hydroxycleroda-3,13-dien-15,16-olide (HCD) from Polyalthia longifolia, rutin, quercetin, and berberine, previously selected through molecular docking.	Diterpenes, Clerodane	62-71	dipeptidyl peptidase 4	Homo sapiens	33-38
26821066-0	2016	The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling.	Diterpenes, Clerodane	4-13	notch receptor 1	Homo sapiens	134-140