PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 27497027-3 2016 Zevalin( ) (ibritumomab tiuxetan) is a radioactive drug product, which is the combination of a beta-emitting isotope, (90)Y, linked to the anti-CD20 monoclonal antibody (mAb), rituximab. ibritumomab tiuxetan 12-32 keratin 20 Homo sapiens 144-148 26025778-0 2015 p53-Based Strategy for Protection of Bone Marrow From Y-90 Ibritumomab Tiuxetan. ibritumomab tiuxetan 59-79 transformation related protein 53, pseudogene Mus musculus 0-3 25705531-0 2015 Late Occurrence of PML in a Patient Treated for Lymphoma with Immunomodulatory Chemotherapies, Bendamustine, Rituximab, and Ibritumomab Tiuxetan. ibritumomab tiuxetan 124-144 PML nuclear body scaffold Homo sapiens 19-22 25677780-2 2015 (90)Y ibritumomab tiuxetan ((90)Y-IT), an anti-CD20 radionuclide-conjugated antibody, has demonstrated clinical efficacy in DLBCL with a favorable toxicity profile. ibritumomab tiuxetan 6-26 keratin 20 Homo sapiens 47-51 25395425-0 2015 Ibritumomab consolidation after 3 cycles of CHOP plus radiotherapy in high-risk limited-stage aggressive B-cell lymphoma: SWOG S0313. ibritumomab tiuxetan 0-11 DNA damage inducible transcript 3 Homo sapiens 44-48 25705531-4 2015 We report the case of a 66-year-old woman who developed PML a year after completion of therapy with rituximab, ibritumomab, and bendamustine. ibritumomab tiuxetan 111-122 PML nuclear body scaffold Homo sapiens 56-59 25440606-2 2014 Two products targeting the CD20 antigen are approved in the treatment of non-Hodgkin B-cell lymphoma (NHBL): iodine 131-tositumomab and yttrium 90-ibritumomab tiuxetan. ibritumomab tiuxetan 136-167 keratin 20 Homo sapiens 27-31 25596049-7 2014 Ibritumomab tiuxetan (Zevalin) is an anti-CD20 mouse monoclonal antibody labeled with Yttrium-90 (Y-90). ibritumomab tiuxetan 0-20 keratin 20 Homo sapiens 42-46 23875170-3 2013 Today, two products targeting the CD20 antigen are approved: (131)I-tositumomab (Bexxar( )), and (90)Y-ibritumomab tiuxetan (Zevalin( )). ibritumomab tiuxetan 103-123 keratin 20 Homo sapiens 34-38 25379535-2 2014 In a clinical field, two successful examples of this treatment protocol are currently extended by (90)Y-ibritumomab tiuxetan (Zevalin) and (131)I-tositumomab (Bexxar), both of which are anti-CD20 monoclonal antibodies coupled to cytotoxic radioisotopes and are approved for the treatment of non-Hodgkin lymphoma patients. ibritumomab tiuxetan 104-124 keratin 20 Homo sapiens 191-195 21571787-1 2011 UNLABELLED: Targeted radioimmunotherapy with (90)Y-labeled ibritumomab tiuxetan is a novel therapeutic approach for CD20-positive relapsed or refractory non-Hodgkin lymphoma (NHL). ibritumomab tiuxetan 59-79 keratin 20 Homo sapiens 116-120 23049552-0 2012 RIT with Y90-Ibritumomab Tiuxetan in Follicular Non-Hodgkin Lymphoma: Evaluation of Recent Outcomes in a Single Institution. ibritumomab tiuxetan 13-33 Ras like without CAAX 1 Homo sapiens 0-3 22628300-1 2012 To exploit the B-lymphocyte antigen-CD20 binding capacity of the Ibritumomab tiuxetan (IBTN) monoclonal antibody (mAb) for imaging, the over-expression of B cells in non-Hodgkin"s lymphoma (NHL) (a myeloproliferative disorder of the lymphatic system) was investigated. ibritumomab tiuxetan 65-85 membrane spanning 4-domains A1 Homo sapiens 15-40 22628300-1 2012 To exploit the B-lymphocyte antigen-CD20 binding capacity of the Ibritumomab tiuxetan (IBTN) monoclonal antibody (mAb) for imaging, the over-expression of B cells in non-Hodgkin"s lymphoma (NHL) (a myeloproliferative disorder of the lymphatic system) was investigated. ibritumomab tiuxetan 87-91 membrane spanning 4-domains A1 Homo sapiens 15-40 21034409-10 2010 Ibritumomab Tiuxetan and Tositumomab are murine anti-CD20 monoclonal antibodies, not chimeric antibodies. ibritumomab tiuxetan 0-20 keratin 20 Homo sapiens 53-57 21575926-0 2011 (90)Y ibritumomab tiuxetan (Zevalin) combined with BEAM (Z -BEAM) conditioning regimen plus autologous stem cell transplantation in relapsed or refractory low-grade CD20-positive B-cell lymphoma. ibritumomab tiuxetan 6-26 keratin 20 Homo sapiens 165-169 21210565-4 2004 Because of its specific presence on non-Hodgkin lymphoma tumor cells, the antigen is a therapeutic target of different anti-CD20 Abs, such as rituximab for monotherapy or combination therapy with a chemotherapeutic agent, or tositumomab ((131)I-labeled) or ibritumomab ((90)Y-conjugated) for radioimmunotherapy (RIT), all of which are approved by the United States Food and Drug Administration for the treatment of this disease (4). ibritumomab tiuxetan 257-268 membrane-spanning 4-domains, subfamily A, member 1 Mus musculus 124-128 19858392-0 2009 Quantitative PCR analysis for Bcl-2/IgH in a phase III study of Yttrium-90 Ibritumomab Tiuxetan as consolidation of first remission in patients with follicular lymphoma. ibritumomab tiuxetan 64-95 BCL2 apoptosis regulator Homo sapiens 30-35 20542986-1 2010 PURPOSE: This study aimed to evaluate the efficacy and safety of the treatment with (90)Y-ibritumomab tiuxetan following a short-course of rituximab with cyclophosphamide-adriamycin-vincristine-prednisone (R-CHOP) in high-risk elderly patients with previously untreated diffuse large B-cell lymphoma (DLBCL). ibritumomab tiuxetan 90-110 DNA damage inducible transcript 3 Homo sapiens 208-212 20542986-5 2010 Eight (50%) of the 16 patients who achieved less than a complete response with CHOP improved their remission status after (90)Y-ibritumomab tiuxetan administration. ibritumomab tiuxetan 128-139 DNA damage inducible transcript 3 Homo sapiens 79-83 19858392-0 2009 Quantitative PCR analysis for Bcl-2/IgH in a phase III study of Yttrium-90 Ibritumomab Tiuxetan as consolidation of first remission in patients with follicular lymphoma. ibritumomab tiuxetan 64-95 immunoglobulin heavy locus Homo sapiens 36-39 19427037-2 2009 The success of anti-CD20 antibody drugs such as Rituximab, Ibritumomab, and Tositumomab has promoted the development of new generation of anti-CD20 antibodies for therapeutic applications. ibritumomab tiuxetan 59-70 keratin 20 Homo sapiens 20-24 19427037-2 2009 The success of anti-CD20 antibody drugs such as Rituximab, Ibritumomab, and Tositumomab has promoted the development of new generation of anti-CD20 antibodies for therapeutic applications. ibritumomab tiuxetan 59-70 keratin 20 Homo sapiens 143-147 18773247-0 2009 Radioisotopic localization of (90)Yttrium-ibritumomab tiuxetan in patients with CD20+ non-Hodgkin"s lymphoma. ibritumomab tiuxetan 42-62 keratin 20 Homo sapiens 80-84 19642457-2 2009 90Y ibritumomab tiuxetan (Zevalin) combines the specificity of rituximab for the CD20 antigen and the therapeutic effect of beta irradiation. ibritumomab tiuxetan 4-24 keratin 20 Homo sapiens 81-85 19819920-2 2009 A number of trials have shown significantly higher response rates and longer progression-free survival times in patients treated with the CD20-targeted radioimmunoconjugate yttrium-90-ibritumomab tiuxetan compared with the standard of care. ibritumomab tiuxetan 173-204 keratin 20 Homo sapiens 138-142 18927323-2 2008 90Y-ibritumomab is an antibody targeting CD20 receptors on the surface of lymphocytes. ibritumomab tiuxetan 0-15 keratin 20 Homo sapiens 41-45 19061730-3 2008 This radioimmunotherapeutic agent consists of ibritumomab, a murine anti-CD20 monoclonal antibody, conjugated to the metal chelator tiuxetan for retention of the beta emitter (90)Y. ibritumomab tiuxetan 46-57 keratin 20 Homo sapiens 73-77 18268399-11 2008 CONCLUSION: Treatment with 90Y ibritumomab tiuxetan induced a clinically relevant CR in a patient with CD20-positive cHL. ibritumomab tiuxetan 31-51 keratin 20 Homo sapiens 103-107 18194857-2 2008 90Y-ibritumomab tiuxetan is the only therapy approved for use after rituximab failure and is currently indicated in the EU for the treatment of adults with rituximab-relapsed or refractory CD20-positive follicular B-cell NHL. ibritumomab tiuxetan 0-24 keratin 20 Homo sapiens 189-193 18268399-12 2008 Thus, we will expand treatment of relapsed CD20-positive HL with 90Y ibritumomab tiuxetan at our institution. ibritumomab tiuxetan 69-89 keratin 20 Homo sapiens 43-47 16367911-0 2005 Phase I study of radioimmunotherapy with an anti-CD20 murine radioimmunoconjugate ((90)Y-ibritumomab tiuxetan) in relapsed or refractory indolent B-cell lymphoma. ibritumomab tiuxetan 89-109 membrane-spanning 4-domains, subfamily A, member 1 Mus musculus 49-53 20641770-9 2004 Later, ibritumomab (intact murine anti-CD20 MAb), was labeled with (111)In or (90)Y for NHL imaging and therapy (9, 10). ibritumomab tiuxetan 7-18 keratin 20 Homo sapiens 39-43 20641438-0 2004 (111)In-Ibritumomab tiuxetan (111)In-Ibritumomab tiuxetan ((111)In-2B8) is an immunoconjugate of a murine anti-CD20 monoclonal antibody (MAb) that is chelated to (111)In for imaging of lymphoid malignancies (1-3). ibritumomab tiuxetan 8-28 membrane spanning 4-domains A1 Homo sapiens 111-115 20641438-0 2004 (111)In-Ibritumomab tiuxetan (111)In-Ibritumomab tiuxetan ((111)In-2B8) is an immunoconjugate of a murine anti-CD20 monoclonal antibody (MAb) that is chelated to (111)In for imaging of lymphoid malignancies (1-3). ibritumomab tiuxetan 37-57 membrane spanning 4-domains A1 Homo sapiens 111-115 20641438-11 2004 Ibritumomab was developed as an anti-CD20 MAb and was characterized by Reff et al. ibritumomab tiuxetan 0-11 membrane spanning 4-domains A1 Homo sapiens 37-41 17323056-1 2007 BACKGROUND: In January 2004, EMEA approved 90Y-radiolabelled ibritumomab tiuxetan, Zevalin, in Europe for the treatment of adult patients with rituximab-relapsed or -refractory CD20+ follicular B-cell non-Hodgkin"s lymphoma. ibritumomab tiuxetan 61-81 keratin 20 Homo sapiens 177-181 17287964-5 2007 An example for this is the anti-CD20 antibody ibritumomab tiuxetan, which is coupled to 90Yttrium and shows comparable activity to rituximab. ibritumomab tiuxetan 46-66 keratin 20 Homo sapiens 32-36 16826593-1 2006 Radioimmunotherapy (RIT) with Yttrium-90 (90Y) ibritumomab tiuxetan (Zevalin) combines the tumor targeting attributes of a monoclonal antibody against the CD20 antigen and the pure beta-radiation of 90Y. ibritumomab tiuxetan 47-67 keratin 20 Homo sapiens 155-159 17087138-2 2006 90Y-ibritumomab tiuxetan is a monoclonal antibody directed against the CD20 antigen to which a radioactive isotope of yttrium is attached, used for treating follicular lymphomas (FL). ibritumomab tiuxetan 0-24 keratin 20 Homo sapiens 71-75 16690521-1 2006 Yttrium 90 ((90)Y) ibritumomab tiuxetan (Zevalin), a radiolabeled monoclonal antibody against the CD20 antigen, is indicated for the treatment of patients with relapsed or refractory low-grade, follicular, or transformed B-cell non-Hodgkin"s lymphoma (NHL), including patients with rituximab-refractory follicular NHL. ibritumomab tiuxetan 41-48 membrane spanning 4-domains A1 Homo sapiens 98-110 16321828-2 2006 Especially the commercially available anti-CD20 antibody 90Y-ibritumomab tiuxetan is currently under investigation in various trials including dose escalation and autologous hematopoietic progenitor cell support. ibritumomab tiuxetan 57-81 keratin 20 Homo sapiens 43-47 16540013-3 2006 90Y-ibritumomab tiuxetan utilizes a monoclonal anti-CD20 antibody to deliver beta-emitting yttrium-90 to the malignant B-cells. ibritumomab tiuxetan 0-24 keratin 20 Homo sapiens 52-56 17886241-3 2007 Zevalin is a commercially available variation of the murine anti-CD20 antibody ibritumomab coupled to Yttrium 90 via the tiuxetan chelator. ibritumomab tiuxetan 79-90 keratin 20 Homo sapiens 65-69 17396483-1 2007 Tositumomab/iodine-131 tositumomab (Bexxar) and ibritumomab tiuxetan (Zevalin) are radioimmunoconjugates targeting the CD20 antigen. ibritumomab tiuxetan 48-68 keratin 20 Homo sapiens 119-123 16979437-3 2006 In clinical trials, (90)Y ibritumomab tiuxetan has produced rates of response as high as 83% in patients with relapsed or refractory CD20+ NHL. ibritumomab tiuxetan 26-46 keratin 20 Homo sapiens 133-137 16979439-3 2006 Y-90 ibritumomab tiuxetan (Zevalin) and I-131 tositumomab (Bexxar) both recognize the CD-20 surface antigen found on normal and malignant B cells. ibritumomab tiuxetan 5-25 keratin 20 Homo sapiens 86-91 16203814-1 2005 PURPOSE: Targeted radioimmunotherapy with yttrium-90 (90Y)-labeled ibritumomab tiuxetan (Zevalin, IDEC-Biogen, San Diego, CA) has shown significant activity in the treatment of relapsed or refractory CD20+ non-Hodgkin"s lymphoma. ibritumomab tiuxetan 67-87 keratin 20 Homo sapiens 200-204 15802280-4 2005 (90)Y-Ibritumomab tiuxetan (Zevalin); Schering AG, Berlin, Germany), the first RIT approved for use in relapsed/refractory indolent NHL, comprises the murine anti-CD20 monoclonal antibody ibritumomab, covalently linked to the high-energy beta-emitter, yttrium-90, by the chelator, tiuxetan. ibritumomab tiuxetan 6-17 keratin 20 Homo sapiens 163-167 16091197-4 2005 Other studies in indolent NHL suggest that radiolabeled anti-CD20 antibodies (such as I-131 tositumomab and Y-90 ibritumomab tiuxetan) may be useful in relapsed and refractory disease and have potential utility as part of initial treatment as well. ibritumomab tiuxetan 113-133 keratin 20 Homo sapiens 61-65 16111589-1 2005 PURPOSE: To evaluate two potential approaches to predicting site-specific patterns of recurrence after yttrium-90 ibritumomab tiuxetan radioimmunotherapy (RIT) for CD20+ B-cell Non-Hodgkin"s lymphoma. ibritumomab tiuxetan 114-134 keratin 20 Homo sapiens 164-168 16207072-3 2005 This radioimmunoconjugate consists of the monoclonal IgG1 antibody ibritumomab (the murine parent of rituximab) bound to the chelator tiuxetan and linked by a stable thiourea covalent bond to the beta-emitting radionuclide 90Y. ibritumomab tiuxetan 67-78 LOC105243590 Mus musculus 53-57 15786024-6 2005 90Y-ibritumomab tiuxetan comprises the murine IgG1 anti-CD20 antibody ibritumomab, covalently linked to the beta-emitter 90 Y by a chelator tiuxetan. ibritumomab tiuxetan 0-24 keratin 20 Homo sapiens 56-60 15786026-3 2005 Two anti-CD20 RIT agents have now been approved for the treatment of refractory NHL: 90Y-ibritumomab tiuxetan (Zevalin; Biogen Idec Inc, San Diego, CA, and Schering AG, Berlin, Germany) is approved in both the United States and Europe, and 131I-tositumomab (Bexxar; Corixa Corp, Seattle, WA) is approved only in the United States. ibritumomab tiuxetan 85-109 keratin 20 Homo sapiens 9-13 15844660-4 2004 The radioimmunoconjugate 90Y-ibritumomab tiuxetan is directed against the B-cell antigen, CD20. ibritumomab tiuxetan 25-49 keratin 20 Homo sapiens 90-94 16304400-7 2005 Other studies in NHL have clearly demonstrated that radiolabeled anti-CD20 antibodies (such as I-131 tositumomab and Y-90 ibritumomab tiuxetan) may be useful in relapsed and refractory disease, and have potential utility as part of initial treatment as well. ibritumomab tiuxetan 122-142 keratin 20 Homo sapiens 70-74 15016644-0 2004 Durable responses after ibritumomab tiuxetan radioimmunotherapy for CD20+ B-cell lymphoma: long-term follow-up of a phase 1/2 study. ibritumomab tiuxetan 24-44 keratin 20 Homo sapiens 68-72 15498146-1 2004 Targeted radioimmunotherapy, including yttrium 90-labeled ibritumomab tiuxetan (Zevalin) and iodine I 131 tositumomab (Bexxar), has the potential to increase the cure rate for patients with CD20+ B-cell malignancies who are undergoing autologous hematopoietic stem cell transplantation. ibritumomab tiuxetan 58-78 keratin 20 Homo sapiens 190-194 15342663-10 2004 In addition, a phase I study of a radiolabeled anti-CD20 antibody (ibritumomab tiuxetan) was completed in 2003, and a phase II study for indolent B-NHL will be initiated. ibritumomab tiuxetan 67-87 keratin 20 Homo sapiens 52-56 15016644-1 2004 We previously demonstrated that yttrium-90 (Y-90) ibritumomab tiuxetan (Zevalin) radioimmunotherapy (RIT) was safe and effective for relapsed or refractory CD20(+), B-cell, non-Hodgkin lymphoma (NHL). ibritumomab tiuxetan 50-70 keratin 20 Homo sapiens 156-160 14710396-8 2003 This is a conjugate of an anti-CD20 mAb (ibritumomab, the murine parent of rituximab) with the beta-emitter radionuclide (90)Y. ibritumomab tiuxetan 41-52 membrane-spanning 4-domains, subfamily A, member 1 Mus musculus 31-35 15045033-1 2004 This article will review the clinical development of ibritumomab tiuxetan, a yttrium-90-conjugated monoclonal antibody to CD20, for patients with relapsed B-cell non-Hodgkin"s lymphomas. ibritumomab tiuxetan 53-73 keratin 20 Homo sapiens 122-126 15045033-2 2004 Ibritumomab is the murine parent anti-CD20 antibody that was engineered to make the human chimeric antibody rituximab. ibritumomab tiuxetan 0-11 keratin 20 Homo sapiens 38-42 15023434-1 2004 Anti-CD20 antibodies radiolabeled with I-131 tositumomab (Bexxar) or Y-90-Ibritumomab tiuxetan (Zevalin), are similarly efficacious in treating chemotherapy-refractory non-Hodgkin"s lymphoma. ibritumomab tiuxetan 69-94 keratin 20 Homo sapiens 5-9 14529425-6 2003 Radioimmunotherapy with the rituximab and ibritumomab tiuxetan (Zevalin) regimen was recently approved for the treatment of relapsed or refractory low-grade, follicular or CD20+ transformed NHL, including rituximab refractory follicular NHL. ibritumomab tiuxetan 42-62 keratin 20 Homo sapiens 172-176 12837157-3 2003 Upon relapse 3 years later, the patient was treated again with radioimmunotherapy consisting of 90Y-ibritumomab tiuxetan anti-CD20 monoclonal antibody, with a good response and acceptable bone marrow suppression. ibritumomab tiuxetan 96-120 keratin 20 Homo sapiens 126-130 12837157-0 2003 Use of ibritumomab tiuxetan anti-CD20 radioimmunotherapy in a non-Hodgkin"s lymphoma patient previously treated with a yttrium-90-labeled anti-CD22 monoclonal antibody. ibritumomab tiuxetan 7-27 keratin 20 Homo sapiens 33-37 15154741-2 2003 90Y-ibritumomab tiuxetan consists of the anti-CD20 monoclonal antibody (MAb) ibritumomab covalently linked to tiuxetan for chelation of 90Y for therapy. ibritumomab tiuxetan 0-24 keratin 20 Homo sapiens 46-50 12837157-0 2003 Use of ibritumomab tiuxetan anti-CD20 radioimmunotherapy in a non-Hodgkin"s lymphoma patient previously treated with a yttrium-90-labeled anti-CD22 monoclonal antibody. ibritumomab tiuxetan 7-27 CD22 molecule Homo sapiens 143-147 12837157-1 2003 Ibritumomab tiuxetan is a novel radioimmunotherapeutic agent that has a high response rate in relapsed or chemotherapy-refractory CD20+ B-cell non-Hodgkin"s lymphoma. ibritumomab tiuxetan 0-20 keratin 20 Homo sapiens 130-134 16224429-7 2003 This study indicates that immune-based therapies such as rituximab and ibritumomab-tiuxetan (anti-CD20) and epratuzumab (anti-CD22) are feasible in pediatric cases of mature B-cell NHLs. ibritumomab tiuxetan 71-91 keratin 20 Homo sapiens 98-102 12663713-1 2003 PURPOSE: Radioimmunotherapy (RIT) with yttrium-90 ((90)Y)-labeled anti-CD20 antibody ((90)Y ibritumomab tiuxetan; Zevalin, IDEC Pharmaceuticals Corporation, San Diego, CA) has a high rate of tumor response in patients with relapsed or refractory, low-grade, follicular, or transformed B-cell non-Hodgkin"s lymphoma (NHL). ibritumomab tiuxetan 92-112 keratin 20 Homo sapiens 71-75 12621016-1 2003 UNLABELLED: Ibritumomab tiuxetan is an anti-CD20 murine IgG1 kappa monoclonal antibody (ibritumomab) conjugated to the linker-chelator tiuxetan, which securely chelates (111)In for imaging or dosimetry and (90)Y for radioimmunotherapy (RIT). ibritumomab tiuxetan 12-32 keratin 20 Homo sapiens 44-48 12621016-1 2003 UNLABELLED: Ibritumomab tiuxetan is an anti-CD20 murine IgG1 kappa monoclonal antibody (ibritumomab) conjugated to the linker-chelator tiuxetan, which securely chelates (111)In for imaging or dosimetry and (90)Y for radioimmunotherapy (RIT). ibritumomab tiuxetan 88-99 keratin 20 Homo sapiens 44-48 15154742-2 2003 90Y-ibritumomab tiuxetan was the first RIT to be approved for the treatment of relapsed and refractory B-cell non-Hodgkin"s lymphoma (NHL), and consists of the anti-CD20 murine monoclonal antibody, ibritumomab, covalently bound to the linker tiuxetan, which securely chelates the radioactive isotope 90Y. ibritumomab tiuxetan 4-24 keratin 20 Homo sapiens 165-169 15154742-2 2003 90Y-ibritumomab tiuxetan was the first RIT to be approved for the treatment of relapsed and refractory B-cell non-Hodgkin"s lymphoma (NHL), and consists of the anti-CD20 murine monoclonal antibody, ibritumomab, covalently bound to the linker tiuxetan, which securely chelates the radioactive isotope 90Y. ibritumomab tiuxetan 4-15 keratin 20 Homo sapiens 165-169 12074764-7 2002 Ibritumomab is the murine anti-CD20 antibody that was engineered to develop the human chimeric antibody rituximab. ibritumomab tiuxetan 0-11 keratin 20 Homo sapiens 31-35 12468399-6 2002 The radioconjugated anti-CD20 mAbs ibritumomab tiuxetan and I131-tositumomab also have impressive clinical activity in low-grade B-cell NHL, and the former has demonstrated superior CR rates to rituximab. ibritumomab tiuxetan 35-55 keratin 20 Homo sapiens 25-29 11762415-0 2001 Zevalin: 90yttrium labeled anti-CD20 (ibritumomab tiuxetan), a new treatment for non-Hodgkin"s lymphoma. ibritumomab tiuxetan 38-58 keratin 20 Homo sapiens 32-36 11877765-1 2002 BACKGROUND: Zevalin consists of a murine anti-CD20 monoclonal antibody (ibritumomab) conjugated to the linker-chelator tiuxetan, which securely chelates indium-111 ((111)In) for imaging and dosimetry and yttrium-90 ((90)Y) for radioimmunotherapy (RIT). ibritumomab tiuxetan 72-83 keratin 20 Homo sapiens 46-50 11850494-1 2002 90Y-ibritumomab tiuxetan is a novel radioimmunotherapeutic agent recently approved for the treatment of relapsed or refractory low-grade, follicular, or CD20+ transformed non-Hodgkin"s lymphoma (NHL). ibritumomab tiuxetan 0-24 keratin 20 Homo sapiens 153-157 11762415-1 2001 Zevalin (ibritumomab tiuxetan, IDEC-Y2B8) is a murine IgG1 kappa monoclonal antibody conjugated to tiuxetan (MXDTPA) that chelates Yttrium or Indium and is directed against the CD 20 molecules of B lymphocytes. ibritumomab tiuxetan 9-29 keratin 20 Homo sapiens 177-182 11587375-2 2001 Ibritumomab is the murine parent anti-CD20 antibody engineered to make the human chimeric antibody rituximab. ibritumomab tiuxetan 0-11 keratin 20 Homo sapiens 38-42 11226003-3 2000 Ibritumomab is the murine parent anti-CD20 antibody that is linked through a MX-DTPA chelator to yttrium 90 (90Y) to form the radioimmunoconjugate 90Y-ibritumomab tiuxetan (Zevalin; IDEC Pharmaceuticals, San Diego, CA). ibritumomab tiuxetan 0-11 keratin 20 Homo sapiens 38-42 11226003-3 2000 Ibritumomab is the murine parent anti-CD20 antibody that is linked through a MX-DTPA chelator to yttrium 90 (90Y) to form the radioimmunoconjugate 90Y-ibritumomab tiuxetan (Zevalin; IDEC Pharmaceuticals, San Diego, CA). ibritumomab tiuxetan 147-171 keratin 20 Homo sapiens 38-42 34227176-4 2021 Ibritumomab tiuxetan radioimmunotherapy (RIT) is a radioimmunoconjugate of anti-CD20 monoclonal antibody linked to chelator tiuxetan and radioisotope. ibritumomab tiuxetan 0-11 keratin 20 Homo sapiens 80-84 10541376-7 1999 The Ibritumomab antibody targets the CD20 antigen. ibritumomab tiuxetan 4-15 keratin 20 Homo sapiens 37-41 34204102-1 2021 PURPOSE: We prospectively evaluated the feasibility of SPECT-CT/planar organ dosimetry-based radiation dose escalation radioimmunotherapy in patients with recurrent non-Hodgkin"s lymphoma using the theranostic pair of 111In and 90Y anti-CD20 ibritumomab tiuxetan (Zevalin ) at myeloablative radiation-absorbed doses with autologous stem cell support. ibritumomab tiuxetan 264-271 keratin 20 Homo sapiens 237-241 35158894-2 2022 The first clinically approved TDD modalities in lymphoma patients were anti-CD20 radioimmunoconjugates (RIT) 131I-tositumomab and 90Y-ibritumomab-tiuxetan. ibritumomab tiuxetan 134-145 keratin 20 Homo sapiens 76-80