PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
29468758-3	2018	In this study, the inhibitory effects of shikonin on the activity of hCE2 in human liver microsomes are investigated by using fluorescein diacetate (FD), N-(2-butyl-1,3-dioxo-2,3-dihydro-1H-phenalen-6-yl)-2-chloroacetamide (NCEN), and CPT-11 as substrates of hCE2.	ncen	224-228	carboxylesterase 2	Homo sapiens	69-73
33568030-9	2021	Furthermore, the inhibitions of clotrimazole towards hCE2-mediated hydrolysis of FD, NCEN and CPT-11 were all in competitive mode with the Ki values of 0.483 muM, 8.63 muM and 29.0 muM, respectively.	ncen	85-89	carboxylesterase 2	Homo sapiens	53-57
35114918-4	2022	METHODS: The inhibition of hypericin on hCE2 was studied by using N-(2-butyl-1,3-dioxo-2,3-dihydro-1H-phenalen-6-yl)-2-chloroacetamide (NCEN).	ncen	136-140	carboxylesterase 2	Homo sapiens	40-44