PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 33154190-10 2021 Luciferase assay was performed to examine the interaction between miR-483-3p and STAT3. mir-483-3p 66-76 signal transducer and activator of transcription 3 Homo sapiens 81-86 32945363-10 2020 The Wnt signaling, antagonist Dikkopf 2 (DKK2), was targeted and negatively regulated by miR-483-3p. mir-483-3p 89-99 Wnt family member 1 Homo sapiens 4-7 32619931-0 2020 MiR-483-3p inhibition ameliorates myocardial ischemia/reperfusion injury by targeting the MDM4/p53 pathway. mir-483-3p 0-10 MDM4 regulator of p53 Rattus norvegicus 90-94 32619931-0 2020 MiR-483-3p inhibition ameliorates myocardial ischemia/reperfusion injury by targeting the MDM4/p53 pathway. mir-483-3p 0-10 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 95-98 32619931-7 2020 MiR-483-3p inhibitor upregulated MDM4 and Bcl-2, but downregulated p53 and Bax in HR-treated H9c2 cells, whereas miR-483-3p overexpression produced the opposite effects.. mir-483-3p 0-10 MDM4 regulator of p53 Rattus norvegicus 33-37 32619931-7 2020 MiR-483-3p inhibitor upregulated MDM4 and Bcl-2, but downregulated p53 and Bax in HR-treated H9c2 cells, whereas miR-483-3p overexpression produced the opposite effects.. mir-483-3p 0-10 BCL2, apoptosis regulator Rattus norvegicus 42-47 32619931-7 2020 MiR-483-3p inhibitor upregulated MDM4 and Bcl-2, but downregulated p53 and Bax in HR-treated H9c2 cells, whereas miR-483-3p overexpression produced the opposite effects.. mir-483-3p 0-10 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 67-70 32619931-7 2020 MiR-483-3p inhibitor upregulated MDM4 and Bcl-2, but downregulated p53 and Bax in HR-treated H9c2 cells, whereas miR-483-3p overexpression produced the opposite effects.. mir-483-3p 0-10 BCL2 associated X, apoptosis regulator Rattus norvegicus 75-78 32619931-8 2020 Moreover, MDM4 siRNA transfection partially reversed the role of miR-483-3p inhibition in HR injury and p53 pathway inactivation of H9c2 cells. mir-483-3p 65-75 MDM4 regulator of p53 Rattus norvegicus 10-14 32619931-9 2020 In summary, by targeting the MDM4/p53 pathway, miR-483-3p inhibition may alleviate myocardial HR injury. mir-483-3p 47-57 MDM4 regulator of p53 Rattus norvegicus 29-33 32619931-9 2020 In summary, by targeting the MDM4/p53 pathway, miR-483-3p inhibition may alleviate myocardial HR injury. mir-483-3p 47-57 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 34-37 34160728-0 2021 miR-483-3p Promotes IL-33 Production from Fibroblast-Like Synoviocytes by Regulating ERK Signaling in Rheumatoid Arthritis. mir-483-3p 0-10 interleukin 33 Homo sapiens 20-25 34160728-0 2021 miR-483-3p Promotes IL-33 Production from Fibroblast-Like Synoviocytes by Regulating ERK Signaling in Rheumatoid Arthritis. mir-483-3p 0-10 mitogen-activated protein kinase 1 Homo sapiens 85-88 34160728-6 2021 Furthermore, miR-483-3p upregulation activated the ERK signaling pathway. mir-483-3p 13-23 mitogen-activated protein kinase 1 Homo sapiens 51-54 34160728-7 2021 The ERK signaling inhibitor PD98059 partly reversed the elevation of IL-33 levels mediated by miR-483-3p overexpression. mir-483-3p 94-104 mitogen-activated protein kinase 1 Homo sapiens 4-7 34160728-7 2021 The ERK signaling inhibitor PD98059 partly reversed the elevation of IL-33 levels mediated by miR-483-3p overexpression. mir-483-3p 94-104 interleukin 33 Homo sapiens 69-74 35222797-7 2022 Overexpression of miR-483-3p in ECs inhibited Ang II-induced endothelial dysfunction, revealed by the decreased expression of TGF-beta, CTGF, ACE1, and ET-1. mir-483-3p 18-28 transforming growth factor alpha Homo sapiens 126-134 35222797-7 2022 Overexpression of miR-483-3p in ECs inhibited Ang II-induced endothelial dysfunction, revealed by the decreased expression of TGF-beta, CTGF, ACE1, and ET-1. mir-483-3p 18-28 cellular communication network factor 2 Homo sapiens 136-140 35222797-7 2022 Overexpression of miR-483-3p in ECs inhibited Ang II-induced endothelial dysfunction, revealed by the decreased expression of TGF-beta, CTGF, ACE1, and ET-1. mir-483-3p 18-28 angiotensin I converting enzyme Homo sapiens 142-146 35222797-7 2022 Overexpression of miR-483-3p in ECs inhibited Ang II-induced endothelial dysfunction, revealed by the decreased expression of TGF-beta, CTGF, ACE1, and ET-1. mir-483-3p 18-28 endothelin 1 Homo sapiens 152-156 33659208-0 2020 miR-483-3p, Mediated by KLF9, Functions as Tumor Suppressor in Testicular Seminoma via Targeting MMP9. mir-483-3p 0-10 Kruppel like factor 9 Homo sapiens 24-28 33659208-0 2020 miR-483-3p, Mediated by KLF9, Functions as Tumor Suppressor in Testicular Seminoma via Targeting MMP9. mir-483-3p 0-10 TSC complex subunit 1 Homo sapiens 43-59 33659208-0 2020 miR-483-3p, Mediated by KLF9, Functions as Tumor Suppressor in Testicular Seminoma via Targeting MMP9. mir-483-3p 0-10 matrix metallopeptidase 9 Homo sapiens 97-101 33659208-10 2020 Mechanically, miR-483-3p negatively regulated MMP9 by directly binding to its 3"-UTR. mir-483-3p 14-24 matrix metallopeptidase 9 Homo sapiens 46-50 33659208-13 2020 Conclusions: In general, our study suggested that miR-483-3p could inhibit the cell growth, migration, and invasion of testicular SEM by targeting MMP9. mir-483-3p 50-60 matrix metallopeptidase 9 Homo sapiens 147-151 32682111-0 2020 miR-483-3p promotes cell proliferation and suppresses apoptosis in rheumatoid arthritis fibroblast-like synoviocytes by targeting IGF-1. mir-483-3p 0-10 insulin like growth factor 1 Homo sapiens 130-135 32682111-8 2020 IGF-1 silencing partially restored cell proliferation, the G0/G1-to-S phase transition, and apoptosis suppression in RA FLSs via miR-483-3p inhibition. mir-483-3p 129-139 insulin like growth factor 1 Homo sapiens 0-5 32682111-9 2020 Our results showed that miR-483-3p promotes RA FLSs proliferation by targeting IGF-1, suggesting a potential strategy for diagnostic and treatment strategy for RA. mir-483-3p 24-34 insulin like growth factor 1 Homo sapiens 79-84 32945363-0 2020 miR-483-3p promotes the osteogenesis of human osteoblasts by targeting Dikkopf 2 (DKK2) and the Wnt signaling pathway. mir-483-3p 0-10 Wnt family member 1 Homo sapiens 96-99 32945363-8 2020 In miR-483-3p-overexpressing human osteoblasts, cell viability, DNA synthesis capacity and osteogenesis were promoted, and the protein levels of Wnt1, beta-catenin and cyclin D1 were increased. mir-483-3p 3-13 Wnt family member 1 Homo sapiens 145-149 32945363-8 2020 In miR-483-3p-overexpressing human osteoblasts, cell viability, DNA synthesis capacity and osteogenesis were promoted, and the protein levels of Wnt1, beta-catenin and cyclin D1 were increased. mir-483-3p 3-13 catenin beta 1 Homo sapiens 151-163 32945363-8 2020 In miR-483-3p-overexpressing human osteoblasts, cell viability, DNA synthesis capacity and osteogenesis were promoted, and the protein levels of Wnt1, beta-catenin and cyclin D1 were increased. mir-483-3p 3-13 cyclin D1 Homo sapiens 168-177 31702021-0 2019 miR-483-3p regulates osteogenic differentiation of bone marrow mesenchymal stem cells by targeting STAT1. mir-483-3p 0-10 signal transducer and activator of transcription 1 Mus musculus 99-104 34637043-10 2022 Luciferase reporter gene assay and western blot analysis were performed to detect the interaction between miR-483-3p and IGF-1. mir-483-3p 106-116 insulin like growth factor 1 Homo sapiens 121-126