PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21070867-10	2011	GW501516-induced PPARbeta/delta activation can attenuate the inflammatory response induced in human cardiac AC16 cells exposed to the saturated fatty acid palmitate and in mice fed a high-fat diet.	saturated fatty acid palmitate	134-164	peroxisome proliferator activated receptor delta	Homo sapiens	17-25
21478880-3	2011	We show that the saturated fatty acid palmitate, but not unsaturated oleate, induces the activation of the NLRP3-ASC inflammasome, causing caspase-1, IL-1beta and IL-18 production.	saturated fatty acid palmitate	17-47	NLR family pyrin domain containing 3	Homo sapiens	107-112
21478880-3	2011	We show that the saturated fatty acid palmitate, but not unsaturated oleate, induces the activation of the NLRP3-ASC inflammasome, causing caspase-1, IL-1beta and IL-18 production.	saturated fatty acid palmitate	17-47	PYD and CARD domain containing	Homo sapiens	113-116
21478880-3	2011	We show that the saturated fatty acid palmitate, but not unsaturated oleate, induces the activation of the NLRP3-ASC inflammasome, causing caspase-1, IL-1beta and IL-18 production.	saturated fatty acid palmitate	17-47	caspase 1	Homo sapiens	139-148
21478880-3	2011	We show that the saturated fatty acid palmitate, but not unsaturated oleate, induces the activation of the NLRP3-ASC inflammasome, causing caspase-1, IL-1beta and IL-18 production.	saturated fatty acid palmitate	17-47	interleukin 1 beta	Homo sapiens	150-158
21478880-3	2011	We show that the saturated fatty acid palmitate, but not unsaturated oleate, induces the activation of the NLRP3-ASC inflammasome, causing caspase-1, IL-1beta and IL-18 production.	saturated fatty acid palmitate	17-47	interleukin 18	Homo sapiens	163-168
31623832-0	2019	The saturated fatty acid palmitate induces insulin resistance through Smad3-mediated down-regulation of FNDC5 in myotubes.	saturated fatty acid palmitate	4-34	insulin	Homo sapiens	43-50
20022932-2	2010	Here we evaluated the effect of the saturated fatty acid palmitate and the monounsaturated fatty acid oleate on Toll-like receptors (TLR)-2 and -4 and cyclooxygenase 2 (COX-2) expression and examined whether the inhibition of this enzyme modulates fatty acid-induced inflammation.	saturated fatty acid palmitate	36-66	prostaglandin-endoperoxide synthase 2	Homo sapiens	151-167
19521344-6	2009	Interestingly, the saturated fatty acid palmitate, a major component of high fat diets, augmented expression of 12/15-LO in vitro.	saturated fatty acid palmitate	19-49	arachidonate 15-lipoxygenase	Mus musculus	112-120
18770866-1	2008	Fatty acid synthase (FASN) is the enzyme responsible for the endogenous synthesis of the saturated fatty acid palmitate.	saturated fatty acid palmitate	89-119	fatty acid synthase	Mus musculus	0-19
18770866-1	2008	Fatty acid synthase (FASN) is the enzyme responsible for the endogenous synthesis of the saturated fatty acid palmitate.	saturated fatty acid palmitate	89-119	fatty acid synthase	Mus musculus	21-25
18060381-5	2008	In L6 myotubes, inhibition of TLR-4 activity substantially reduced the capacity of the saturated fatty acid palmitate to induce insulin resistance.	saturated fatty acid palmitate	87-117	toll-like receptor 4	Mus musculus	30-35
17337731-6	2007	By contrast, the saturated fatty acid palmitate induced insulin resistance.	saturated fatty acid palmitate	17-47	insulin	Homo sapiens	56-63
11278654-3	2001	The saturated fatty acid palmitate, but not the monounsaturated fatty acid oleate, induced programmed cell death as determined by annexin V positivity, caspase 3 activity, and DNA laddering.	saturated fatty acid palmitate	4-34	caspase-3	Cricetulus griseus	152-161
35508494-2	2022	However, GLP-1 secretion also follows a circadian rhythm which is disrupted by the saturated fatty acid palmitate in vitro and high-fat diet (HFD) feeding in vivo.	saturated fatty acid palmitate	83-113	glucagon	Mus musculus	9-14
20178457-7	2010	Addition of antioxidants SOD (superoxide dismutase), Cat (catalase) and NAC (N-acetylcysteine) attenuated H(2)O(2) or the saturated fatty acid palmitate-dependent effects, but not cytokine-induced dysfunction.	saturated fatty acid palmitate	122-152	catalase	Mus musculus	53-56
20178457-7	2010	Addition of antioxidants SOD (superoxide dismutase), Cat (catalase) and NAC (N-acetylcysteine) attenuated H(2)O(2) or the saturated fatty acid palmitate-dependent effects, but not cytokine-induced dysfunction.	saturated fatty acid palmitate	122-152	catalase	Mus musculus	58-66
20185762-4	2010	In C2C12 skeletal muscle cells, the PPARdelta agonist GW501516 prevented phosphorylation of insulin receptor substrate-1 at Ser(307) and the inhibition of insulin-stimulated Akt phosphorylation caused by exposure to the saturated fatty acid palmitate.	saturated fatty acid palmitate	220-250	peroxisome proliferator activator receptor delta	Mus musculus	36-45
20185762-4	2010	In C2C12 skeletal muscle cells, the PPARdelta agonist GW501516 prevented phosphorylation of insulin receptor substrate-1 at Ser(307) and the inhibition of insulin-stimulated Akt phosphorylation caused by exposure to the saturated fatty acid palmitate.	saturated fatty acid palmitate	220-250	insulin receptor substrate 1	Mus musculus	92-120
18281277-2	2008	Exposure of cells to the saturated fatty acid palmitate led to enhanced diacylglycerol levels and the consequent activation of the protein kinase C/nuclear factor kappaB pathway, finally resulting in enhanced interleukin 6 secretion and down-regulation of the expression of genes involved in the control of the oxidative capacity of skeletal muscle (peroxisome proliferator-activated receptor (PPAR)gamma-coactivator 1alpha) and triglyceride synthesis (acyl-coenzyme A: diacylglycerol acyltransferase 2).	saturated fatty acid palmitate	25-55	interleukin 6	Homo sapiens	209-222
32221369-7	2020	Exposure of macrophages to the saturated fatty acid palmitate increased glycolysis and HIF-1alpha expression, which culminated in IL-1beta induction thereby simulating pseudohypoxia.	saturated fatty acid palmitate	31-61	hypoxia inducible factor 1, alpha subunit	Mus musculus	87-97
32221369-7	2020	Exposure of macrophages to the saturated fatty acid palmitate increased glycolysis and HIF-1alpha expression, which culminated in IL-1beta induction thereby simulating pseudohypoxia.	saturated fatty acid palmitate	31-61	interleukin 1 alpha	Mus musculus	130-138
31866205-0	2020	Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade.	saturated fatty acid palmitate	10-40	cyclin dependent kinase 1	Homo sapiens	103-107
31866205-0	2020	Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade.	saturated fatty acid palmitate	10-40	sirtuin 3	Homo sapiens	108-113
31866205-0	2020	Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade.	saturated fatty acid palmitate	10-40	carnitine palmitoyltransferase 2	Homo sapiens	114-118
31623832-0	2019	The saturated fatty acid palmitate induces insulin resistance through Smad3-mediated down-regulation of FNDC5 in myotubes.	saturated fatty acid palmitate	4-34	SMAD family member 3	Homo sapiens	70-75
31623832-0	2019	The saturated fatty acid palmitate induces insulin resistance through Smad3-mediated down-regulation of FNDC5 in myotubes.	saturated fatty acid palmitate	4-34	fibronectin type III domain containing 5	Homo sapiens	104-109
31769755-4	2019	Using siRNA combined with lipidomics and membrane fluidity assays (FRAP and Laurdan dye staining) we further show that the human ACSL1 potentiates lipotoxicity by the saturated fatty acid palmitate: silencing ACSL1 protects against the membrane rigidifying effects of palmitate and acts as a suppressor of AdipoR2 knockdown, thus echoing the C. elegans findings.	saturated fatty acid palmitate	167-197	acyl-CoA synthetase long chain family member 1	Homo sapiens	129-134
31769755-4	2019	Using siRNA combined with lipidomics and membrane fluidity assays (FRAP and Laurdan dye staining) we further show that the human ACSL1 potentiates lipotoxicity by the saturated fatty acid palmitate: silencing ACSL1 protects against the membrane rigidifying effects of palmitate and acts as a suppressor of AdipoR2 knockdown, thus echoing the C. elegans findings.	saturated fatty acid palmitate	167-197	acyl-CoA synthetase long chain family member 1	Homo sapiens	209-214
31443599-11	2019	These findings suggest that the signaling cross-talk between saturated fatty acid palmitate and TNF-alpha may be a key driver in obesity-associated chronic inflammation via an excessive production of IL-8.	saturated fatty acid palmitate	61-91	C-X-C motif chemokine ligand 8	Homo sapiens	200-204
31373312-8	2019	In cultured primary renal tubular epithelial cells (TECs), administration of saturated fatty acid palmitate resulted in an upregulation of KIM-1, osteopontin, and CD44, which was greatly attenuated by U0126, an inhibitor of extracellular signal-regulated kinase (ERK)1/2.	saturated fatty acid palmitate	77-107	CD44 molecule (Indian blood group)	Rattus norvegicus	163-167
31373312-8	2019	In cultured primary renal tubular epithelial cells (TECs), administration of saturated fatty acid palmitate resulted in an upregulation of KIM-1, osteopontin, and CD44, which was greatly attenuated by U0126, an inhibitor of extracellular signal-regulated kinase (ERK)1/2.	saturated fatty acid palmitate	77-107	mitogen activated protein kinase 3	Rattus norvegicus	224-270
31373312-8	2019	In cultured primary renal tubular epithelial cells (TECs), administration of saturated fatty acid palmitate resulted in an upregulation of KIM-1, osteopontin, and CD44, which was greatly attenuated by U0126, an inhibitor of extracellular signal-regulated kinase (ERK)1/2.	saturated fatty acid palmitate	77-107	hepatitis A virus cellular receptor 1	Rattus norvegicus	139-144
31373312-8	2019	In cultured primary renal tubular epithelial cells (TECs), administration of saturated fatty acid palmitate resulted in an upregulation of KIM-1, osteopontin, and CD44, which was greatly attenuated by U0126, an inhibitor of extracellular signal-regulated kinase (ERK)1/2.	saturated fatty acid palmitate	77-107	secreted phosphoprotein 1	Rattus norvegicus	146-157
30353973-8	2019	Thus, we conclude that the high concentration of the saturated fatty acid palmitate and glucose in vitro influences PC3 cells and stimulates cellular activities related to carcinogenesis such as cell proliferation, migration, and oxidative stress in different ways.	saturated fatty acid palmitate	53-83	chromobox 8	Homo sapiens	116-119
30716364-0	2019	Regulation of Gpr173 expression, a putative phoenixin receptor, by saturated fatty acid palmitate and endocrine-disrupting chemical bisphenol A through a p38-mediated mechanism in immortalized hypothalamic neurons.	saturated fatty acid palmitate	67-97	G protein-coupled receptor 173	Homo sapiens	14-20
30127714-10	2018	Conclusion: Altogether, our results demonstrate that a diet rich in the saturated fatty acid palmitate can modulate levels of alpha-syn, TH, dopamine, and serotonin which all are proteins and neurochemicals that play key roles in increasing or reducing the risk for many neurodegenerative diseases including PD.	saturated fatty acid palmitate	72-102	synuclein, alpha	Mus musculus	126-135
30459603-5	2018	We found that TXNIP mediated the saturated fatty acid palmitate (PA)-induced insulin resistance in C2C12 myotubes.	saturated fatty acid palmitate	33-63	thioredoxin interacting protein	Mus musculus	14-19
29159216-7	2017	The data is related to a research article entitled "MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells" (Yang et al., 2016) [1].	saturated fatty acid palmitate	76-106	microRNA 1271	Homo sapiens	52-60
29852167-0	2018	Saturated fatty acid palmitate negatively regulates autophagy by promoting ATG5 protein degradation in meniscus cells.	saturated fatty acid palmitate	0-30	autophagy related 5	Homo sapiens	75-79
29159216-7	2017	The data is related to a research article entitled "MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells" (Yang et al., 2016) [1].	saturated fatty acid palmitate	76-106	insulin receptor	Homo sapiens	157-161
29159216-7	2017	The data is related to a research article entitled "MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells" (Yang et al., 2016) [1].	saturated fatty acid palmitate	76-106	insulin receptor substrate 1	Homo sapiens	166-171
28584168-2	2017	We tested in primary human myotubes if insulin resistance induced by saturated fatty acid palmitate can be ameliorated by concomitant exposure to unsaturated fatty acid oleate.	saturated fatty acid palmitate	69-99	insulin	Homo sapiens	39-46
28545881-0	2017	High fat-diet and saturated fatty acid palmitate inhibits IGF-1 function in chondrocytes.	saturated fatty acid palmitate	18-48	insulin like growth factor 1	Homo sapiens	58-63
28980863-2	2017	The objective of this study was to determine the effects of the saturated fatty acid palmitate on IAPP levels in human beta-cells.	saturated fatty acid palmitate	64-94	islet amyloid polypeptide	Homo sapiens	98-102
28478227-2	2017	In vessel endothelial cells, saturated fatty acid palmitate (PA) stimulation induced HK-II detachment from mitochondria due to cellular acidification.	saturated fatty acid palmitate	29-59	hexokinase 2	Mus musculus	85-90
27154056-4	2016	Probing the bioenergetics of rat and human myoblasts in real time we show here that the saturated fatty acid palmitate lowers the rate and coupling efficiency of oxidative phosphorylation under conditions it causes insulin resistance.	saturated fatty acid palmitate	88-118	insulin	Homo sapiens	215-222
28644409-4	2017	Quercetin markedly reduced the production of inflammatory mediators (monocyte chemoattractant protein (MCP)-1, interleukin (IL-6), IL-1beta, nitric oxide) by microglia stimulated with saturated fatty acid palmitate and/or lipid-laden microglia-conditioned medium.	saturated fatty acid palmitate	184-214	interleukin 1 beta	Mus musculus	131-139
28282788-3	2017	In the present study, we showed that berberine (BBR) significantly suppressed saturated fatty acid palmitate (PA)-induced NLRP3 inflammasome activation and interleukin-1beta (IL-1beta) release in macrophages, which was one of the most important mediators in the insulin sensitivity of adipose tissue.	saturated fatty acid palmitate	78-108	NLR family, pyrin domain containing 3	Mus musculus	122-127
27900351-4	2016	Further extensive insights into the implications of miRNAs, particularly miR-1271, in HepG2 cells can be found in "MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells" (W.M.	saturated fatty acid palmitate	139-169	insulin receptor	Homo sapiens	220-224
27900351-4	2016	Further extensive insights into the implications of miRNAs, particularly miR-1271, in HepG2 cells can be found in "MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells" (W.M.	saturated fatty acid palmitate	139-169	insulin receptor substrate 1	Homo sapiens	229-234
28377722-4	2017	Herein, we tested the hypothesis that curcumin action in ER protein quality control was related to improvement of insulin resistance in human umbilical vein endothelial cells (HUVECs) cultured with saturated fatty acid palmitate.	saturated fatty acid palmitate	198-228	insulin	Homo sapiens	114-121
27637015-5	2016	In HepG2 cells, BNL-CL2 cells, and murine primary hepatocytes, Rubicon was posttranscriptionally up-regulated by supplementation with saturated fatty acid palmitate.	saturated fatty acid palmitate	134-164	RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein	Mus musculus	63-70
27613089-0	2016	MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells.	saturated fatty acid palmitate	24-54	membrane associated ring-CH-type finger 8	Homo sapiens	0-3
27613089-0	2016	MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells.	saturated fatty acid palmitate	24-54	insulin receptor	Homo sapiens	105-109
27613089-0	2016	MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells.	saturated fatty acid palmitate	24-54	insulin receptor substrate 1	Homo sapiens	114-119
27235148-5	2016	FoxO1 protein was significantly elevated in cultured endothelial cells exposed to the saturated fatty acid palmitate or the proinflammatory cytokine TNF-alpha.	saturated fatty acid palmitate	86-116	forkhead box O1	Mus musculus	0-5
26923440-0	2016	Induction of Gnrh mRNA expression by the omega-3 polyunsaturated fatty acid docosahexaenoic acid and the saturated fatty acid palmitate in a GnRH-synthesizing neuronal cell model, mHypoA-GnRH/GFP.	saturated fatty acid palmitate	105-135	gonadotropin releasing hormone 1	Homo sapiens	13-17
26135354-5	2015	XBP1 inhibition potentiated cell death induced by pro-inflammatory cytokines or the saturated fatty acid palmitate in MIN6 beta-cells.	saturated fatty acid palmitate	84-114	X-box binding protein 1	Mus musculus	0-4
26162692-10	2015	Finally, the antagonistic effect of Rs-LPS on TLR4 was demonstrated by our in vitro studies showing that Rs-LPS inhibited IL-6 secretion from macrophages and endothelial cells stimulated by LPS or LPS plus saturated fatty acid palmitate.	saturated fatty acid palmitate	206-236	toll-like receptor 4	Mus musculus	46-50
26162692-10	2015	Finally, the antagonistic effect of Rs-LPS on TLR4 was demonstrated by our in vitro studies showing that Rs-LPS inhibited IL-6 secretion from macrophages and endothelial cells stimulated by LPS or LPS plus saturated fatty acid palmitate.	saturated fatty acid palmitate	206-236	interleukin 6	Mus musculus	122-126
24584118-4	2014	Netrin-1, whose expression is induced in macrophages by the saturated fatty acid palmitate, acts via its receptor Unc5b to block their migration.	saturated fatty acid palmitate	60-90	unc-5 netrin receptor B	Mus musculus	114-119
24892004-2	2014	It has been shown that exposure to saturated fatty acid palmitate can cause insulin resistance in skeletal muscle cells.	saturated fatty acid palmitate	35-65	insulin	Homo sapiens	76-83
24532802-4	2014	We have shown previously that IL-1beta secretion is induced in primary macrophages exposed to the dietary saturated fatty acid palmitate in combination with LPS.	saturated fatty acid palmitate	106-136	interleukin 1 beta	Homo sapiens	30-38
26075729-1	2015	Elevated levels of serum saturated fatty acid palmitate have been shown to promote insulin resistance, increase cellular ROS production, and trigger cell apoptosis in hepatocytes during the development of obesity.	saturated fatty acid palmitate	25-55	insulin	Homo sapiens	83-90
24584118-4	2014	Netrin-1, whose expression is induced in macrophages by the saturated fatty acid palmitate, acts via its receptor Unc5b to block their migration.	saturated fatty acid palmitate	60-90	netrin 1	Mus musculus	0-8
24396871-2	2013	We recently showed that a lipotoxic shock caused by exposure of beta-cells to the saturated fatty acid palmitate strongly increases Nur77 expression.	saturated fatty acid palmitate	82-112	nuclear receptor subfamily 4 group A member 1	Homo sapiens	132-137
23850687-0	2013	Saturated fatty acid palmitate induces extracellular release of histone H3: a possible mechanistic basis for high-fat diet-induced inflammation and thrombosis.	saturated fatty acid palmitate	0-30	H3 clustered histone 7	Mus musculus	64-74
24512852-2	2013	We recently showed that a lipotoxic shock caused by exposure of beta-cells to the saturated fatty acid palmitate strongly increases Nur77 expression.	saturated fatty acid palmitate	82-112	nuclear receptor subfamily 4 group A member 1	Homo sapiens	132-137
24052904-6	2013	Moreover, increased caspase-1 dependent IL-1beta secretion with increased expression of NLRP3 inflammasome and phospho-NFkappaBp65 were observed in LGALS3(-/-) peritoneal macrophages stimulated in vitro by lipopolysaccharide and/or saturated fatty acid palmitate.	saturated fatty acid palmitate	232-262	caspase 1	Mus musculus	20-29
24052904-6	2013	Moreover, increased caspase-1 dependent IL-1beta secretion with increased expression of NLRP3 inflammasome and phospho-NFkappaBp65 were observed in LGALS3(-/-) peritoneal macrophages stimulated in vitro by lipopolysaccharide and/or saturated fatty acid palmitate.	saturated fatty acid palmitate	232-262	interleukin 1 beta	Mus musculus	40-48
24052904-6	2013	Moreover, increased caspase-1 dependent IL-1beta secretion with increased expression of NLRP3 inflammasome and phospho-NFkappaBp65 were observed in LGALS3(-/-) peritoneal macrophages stimulated in vitro by lipopolysaccharide and/or saturated fatty acid palmitate.	saturated fatty acid palmitate	232-262	NLR family, pyrin domain containing 3	Mus musculus	88-93
24052904-6	2013	Moreover, increased caspase-1 dependent IL-1beta secretion with increased expression of NLRP3 inflammasome and phospho-NFkappaBp65 were observed in LGALS3(-/-) peritoneal macrophages stimulated in vitro by lipopolysaccharide and/or saturated fatty acid palmitate.	saturated fatty acid palmitate	232-262	lectin, galactose binding, soluble 3	Mus musculus	148-154
23904453-6	2013	Mechanistic studies showed that the saturated fatty acid palmitate activated extracellular signal-regulated kinase (ERK) and inhibited Sort1 protein by mechanisms involving Sort1 protein ubiquitination and degradation.	saturated fatty acid palmitate	36-66	mitogen-activated protein kinase 1	Mus musculus	77-114
23904453-6	2013	Mechanistic studies showed that the saturated fatty acid palmitate activated extracellular signal-regulated kinase (ERK) and inhibited Sort1 protein by mechanisms involving Sort1 protein ubiquitination and degradation.	saturated fatty acid palmitate	36-66	mitogen-activated protein kinase 1	Mus musculus	116-119
23904453-6	2013	Mechanistic studies showed that the saturated fatty acid palmitate activated extracellular signal-regulated kinase (ERK) and inhibited Sort1 protein by mechanisms involving Sort1 protein ubiquitination and degradation.	saturated fatty acid palmitate	36-66	sortilin 1	Mus musculus	135-140
23904453-6	2013	Mechanistic studies showed that the saturated fatty acid palmitate activated extracellular signal-regulated kinase (ERK) and inhibited Sort1 protein by mechanisms involving Sort1 protein ubiquitination and degradation.	saturated fatty acid palmitate	36-66	sortilin 1	Mus musculus	173-178
23850687-4	2013	Here, we show that histone H3, a major protein component of chromatin, is released into the extracellular space when mice are fed a HFD or macrophages are stimulated with the saturated fatty acid palmitate.	saturated fatty acid palmitate	175-205	H3 clustered histone 7	Mus musculus	19-29
23531513-7	2013	JNK and endoplasmic reticulum stress responses to the saturated fatty acid palmitate were attenuated as well, an effect mimicked by the knockdown of PPARgamma.	saturated fatty acid palmitate	54-84	mitogen-activated protein kinase 8	Homo sapiens	0-3
23531513-7	2013	JNK and endoplasmic reticulum stress responses to the saturated fatty acid palmitate were attenuated as well, an effect mimicked by the knockdown of PPARgamma.	saturated fatty acid palmitate	54-84	peroxisome proliferator activated receptor gamma	Homo sapiens	149-158
23349493-6	2013	In vitro stimulation of LGALS3(-/-) peritoneal macrophages with lipopolysaccharide (LPS) and saturated fatty acid palmitate caused increased caspase-1-dependent IL-1beta production and increased phosphorylation of NF-kappaB p65 compared with WT cells.	saturated fatty acid palmitate	93-123	lectin, galactose binding, soluble 3	Mus musculus	24-30
23349493-6	2013	In vitro stimulation of LGALS3(-/-) peritoneal macrophages with lipopolysaccharide (LPS) and saturated fatty acid palmitate caused increased caspase-1-dependent IL-1beta production and increased phosphorylation of NF-kappaB p65 compared with WT cells.	saturated fatty acid palmitate	93-123	caspase 1	Mus musculus	141-150
23349493-6	2013	In vitro stimulation of LGALS3(-/-) peritoneal macrophages with lipopolysaccharide (LPS) and saturated fatty acid palmitate caused increased caspase-1-dependent IL-1beta production and increased phosphorylation of NF-kappaB p65 compared with WT cells.	saturated fatty acid palmitate	93-123	interleukin 1 beta	Mus musculus	161-169
23349493-6	2013	In vitro stimulation of LGALS3(-/-) peritoneal macrophages with lipopolysaccharide (LPS) and saturated fatty acid palmitate caused increased caspase-1-dependent IL-1beta production and increased phosphorylation of NF-kappaB p65 compared with WT cells.	saturated fatty acid palmitate	93-123	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	224-227