PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
17000675-4	2006	RESULTS: Levels of S100A11 were significantly higher in pancreatic cancer (n=22) and IPMN (n=18) bulk tissues than in nonneoplastic bulk tissues (n=22; P<0.0001 for both).	ipmn	85-89	S100 calcium binding protein A11	Homo sapiens	19-26
32939577-7	2020	Capturing KRAS and GNAS could also provide genetic evidence in patients with IPMN-associated PDA and undergoing pancreatic surveillance.	ipmn	77-81	KRAS proto-oncogene, GTPase	Homo sapiens	10-14
32939577-7	2020	Capturing KRAS and GNAS could also provide genetic evidence in patients with IPMN-associated PDA and undergoing pancreatic surveillance.	ipmn	77-81	GNAS complex locus	Homo sapiens	19-23
32934653-5	2020	We identified KRAS and GNAS mutations in 35 (57%) and 40 (66%) IPMN cases, respectively.	ipmn	63-67	KRAS proto-oncogene, GTPase	Homo sapiens	14-18
32934653-5	2020	We identified KRAS and GNAS mutations in 35 (57%) and 40 (66%) IPMN cases, respectively.	ipmn	63-67	GNAS complex locus	Homo sapiens	23-27
32541631-9	2020	CONCLUSIONS: Serum anti-p53 antibody can serve as a surrogate marker for TP53 alterations and help predict the presence of HGD/INV in cases with IPMN, in combination with CEA and CA 19-9.	ipmn	145-149	tumor protein p53	Homo sapiens	24-27
31404021-5	2019	RESULTS: TP53 mutation rates in D-PDC, C-PDC, and noninvasive IPMN were 67%, 66%, and 10%, respectively.	ipmn	62-66	tumor protein p53	Homo sapiens	9-13
30357576-6	2019	RESULTS: Nuclear SOX9 expression was detected in the epithelial cells of 98% HG IPMN, 93% LG IPMN, 83% PDAC, and 60% BP.	ipmn	80-84	SRY-box transcription factor 9	Homo sapiens	17-21
30357576-6	2019	RESULTS: Nuclear SOX9 expression was detected in the epithelial cells of 98% HG IPMN, 93% LG IPMN, 83% PDAC, and 60% BP.	ipmn	93-97	SRY-box transcription factor 9	Homo sapiens	17-21
30447255-4	2019	The overall HHLA2 positivity was 95% (19/20) in low grade PanIN and 70.73% (29/41) in IPMN.	ipmn	86-90	HERV-H LTR-associating 2	Homo sapiens	12-17
28412205-6	2017	SLC2A1/GLUT1 expression in the mural nodules was recognized in the basal and basolateral cytomembrane of tumor cells and was expressed in 15.4% (2/13) of the IPMN-low, 15.4% (2/13) of the IPMN-int, 71.4% (20/28) of the IPMN-high and 84.6% (22/26) of the IPMN-inv groups.	ipmn	158-162	solute carrier family 2 member 1	Homo sapiens	0-6
28412205-6	2017	SLC2A1/GLUT1 expression in the mural nodules was recognized in the basal and basolateral cytomembrane of tumor cells and was expressed in 15.4% (2/13) of the IPMN-low, 15.4% (2/13) of the IPMN-int, 71.4% (20/28) of the IPMN-high and 84.6% (22/26) of the IPMN-inv groups.	ipmn	158-162	solute carrier family 2 member 1	Homo sapiens	7-12
24714692-8	2014	Analyses of the DNA methylation status of MUC1, MUC2 and MUC4 were useful for differential diagnosis of human pancreatic neoplasms, with specificity and sensitivity of 87% and 80% for PDAC; 100% and 88% for intestinal-type IPMN; and 88% and 77% for gastric-type IPMN, respectively.	ipmn	223-227	mucin 1, cell surface associated	Homo sapiens	42-46
24714692-8	2014	Analyses of the DNA methylation status of MUC1, MUC2 and MUC4 were useful for differential diagnosis of human pancreatic neoplasms, with specificity and sensitivity of 87% and 80% for PDAC; 100% and 88% for intestinal-type IPMN; and 88% and 77% for gastric-type IPMN, respectively.	ipmn	223-227	mucin 4, cell surface associated	Homo sapiens	57-61
24714692-8	2014	Analyses of the DNA methylation status of MUC1, MUC2 and MUC4 were useful for differential diagnosis of human pancreatic neoplasms, with specificity and sensitivity of 87% and 80% for PDAC; 100% and 88% for intestinal-type IPMN; and 88% and 77% for gastric-type IPMN, respectively.	ipmn	262-266	mucin 1, cell surface associated	Homo sapiens	42-46
24714692-8	2014	Analyses of the DNA methylation status of MUC1, MUC2 and MUC4 were useful for differential diagnosis of human pancreatic neoplasms, with specificity and sensitivity of 87% and 80% for PDAC; 100% and 88% for intestinal-type IPMN; and 88% and 77% for gastric-type IPMN, respectively.	ipmn	262-266	mucin 4, cell surface associated	Homo sapiens	57-61
33275808-7	2021	Finally, for the first time, we discovered that GPA33 is expressed in the intestinal-type IPMN, thereby suggesting a novel target for cancer therapy.	ipmn	90-94	glycoprotein A33	Homo sapiens	48-53
33692257-6	2021	PODXL may be a novel, non-invasive diagnostic biomarker for the detection of IPMN.	ipmn	77-81	podocalyxin like	Homo sapiens	0-5
32532597-3	2020	The aim of this study was to clarify transitions in phosphorylated Smad3 signaling during IPMN carcinogenesis.	ipmn	90-94	SMAD family member 3	Homo sapiens	67-72
32424306-6	2020	Volcano plot identified follistatin (FST) as the most upregulated mRNA in IOPN in comparison to the gastric subtype (log2 fold change of 5.34) and the intestinal subtype (that of 5.81) of IPMN/IPNB.	ipmn	188-192	follistatin	Homo sapiens	24-35
32424306-6	2020	Volcano plot identified follistatin (FST) as the most upregulated mRNA in IOPN in comparison to the gastric subtype (log2 fold change of 5.34) and the intestinal subtype (that of 5.81) of IPMN/IPNB.	ipmn	188-192	follistatin	Homo sapiens	37-40
28539816-8	2017	In IPMN with low-grade, intermediate-grade, high-grade dysplasia, associated carcinoma, the expression of hsa-miR-96 was 67%(9/13), 64%(7/11), 43%(3/7) and 27%(7/26) respectively, while the expression of hsa-miR-217 was 77%(10/13), 64%(7/11), 29%(2/7) and 38%(10/26).	ipmn	3-7	microRNA 96	Homo sapiens	106-116
27514845-9	2017	GNAS was positive in 51 patients (47.2%) with IPMN.	ipmn	46-50	GNAS complex locus	Homo sapiens	0-4
24897499-9	2014	In the resected pancreatic tissues, GNAS mutations were detected in 50% of PDAC cases concomitant with IPMN, 33.3% of PDAC cases derived from IPMN, and 66.7% of IPMN cases, while no GNAS mutations were detected in cases of PDAC without IPMN.	ipmn	103-107	GNAS complex locus	Homo sapiens	36-40
24897499-9	2014	In the resected pancreatic tissues, GNAS mutations were detected in 50% of PDAC cases concomitant with IPMN, 33.3% of PDAC cases derived from IPMN, and 66.7% of IPMN cases, while no GNAS mutations were detected in cases of PDAC without IPMN.	ipmn	142-146	GNAS complex locus	Homo sapiens	36-40
24897499-9	2014	In the resected pancreatic tissues, GNAS mutations were detected in 50% of PDAC cases concomitant with IPMN, 33.3% of PDAC cases derived from IPMN, and 66.7% of IPMN cases, while no GNAS mutations were detected in cases of PDAC without IPMN.	ipmn	142-146	GNAS complex locus	Homo sapiens	36-40
24897499-9	2014	In the resected pancreatic tissues, GNAS mutations were detected in 50% of PDAC cases concomitant with IPMN, 33.3% of PDAC cases derived from IPMN, and 66.7% of IPMN cases, while no GNAS mutations were detected in cases of PDAC without IPMN.	ipmn	142-146	GNAS complex locus	Homo sapiens	36-40
16965396-8	2006	Using a suitable cut-off value of 2.5 according to the receiver operating characteristic curve, the incidence of aberrant TFPI-2 methylation in the PPJ by real-time MSP was 18 (62.1%) of 29 PCa patients, one (5.1%) of 17 IPMN and three (14.3%) of 21 CP, respectively.	ipmn	221-225	tissue factor pathway inhibitor 2	Homo sapiens	122-128
17000675-8	2006	In pancreatic juice analyses, cancer-related (n=24; P=0.004) and IPMN-related (n=18; P=0.001) juice expressed significantly higher levels of S100A11 than did chronic pancreatitis-related juice (n=23).	ipmn	65-69	S100 calcium binding protein A11	Homo sapiens	141-148
15879625-10	2005	On the other hand, MUC1 and MUC2 may serve as indicators of the direction of differentiation, i.e., either progression to IDAC or IPMN.	ipmn	130-134	mucin 1, cell surface associated	Homo sapiens	19-23
34674710-3	2021	We recently encountered an extremely rare case of ectopic pancreas in the gastric antrum associated with IPMN possessing a GNAS mutation.	ipmn	105-109	GNAS complex locus	Homo sapiens	123-127
34778955-11	2022	ApoA2-i has the potential to early detect the risk of malignancy of patients with IPMN.	ipmn	82-86	apolipoprotein A2	Homo sapiens	0-5
34944713-7	2021	A two-marker panel of HE4 and CEA significantly outperformed CA19-9 in separating IPMN from chronic pancreatitis (0.841 vs. 0.501).	ipmn	82-86	WAP four-disulfide core domain 2	Homo sapiens	22-25
34172498-9	2021	IPMN showed elevated PGC1alpha, fatty acid beta-oxidation (FAO) gene expression, and FAO-OXPhos.	ipmn	0-4	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	21-30
35018527-3	2022	METHODS: CRISPR/Cas9-mediated GNAS R201H silencing was performed using human primary IPMN-associated pancreatic cancer cells.	ipmn	85-89	GNAS complex locus	Homo sapiens	30-34