PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 30867382-1 2019 Elobixibat is a novel small-molecule that acts as an inhibitor of the ileal bile acid transporter (IBAT), and used for chronic constipation in Japan. elobixibat 0-10 solute carrier family 10 member 2 Homo sapiens 99-103 26197999-8 2015 Another study, in 36 patients with CC treated with high dose elobixibat; 15 mg or 20 mg/day or placebo for 14 days, was evaluated for changes in GLP-1. elobixibat 61-71 glucagon Homo sapiens 145-150 30129377-0 2018 Elobixibat, the first-in-class Ileal Bile Acid Transporter inhibitor, for the treatment of Chronic Idiopathic Constipation. elobixibat 0-10 solute carrier family 10 member 2 Homo sapiens 31-58 30204504-6 2018 Areas covered: Rationale for IBAT inhibitor in therapeutics, and preclinical and clinical pharmacology of elobixibat: In vitro, elobixibat is a highly potent, selective IBAT inhibitor. elobixibat 128-138 solute carrier family 10 member 2 Homo sapiens 29-33 30204504-6 2018 Areas covered: Rationale for IBAT inhibitor in therapeutics, and preclinical and clinical pharmacology of elobixibat: In vitro, elobixibat is a highly potent, selective IBAT inhibitor. elobixibat 128-138 solute carrier family 10 member 2 Homo sapiens 169-173 21545606-0 2011 Randomised clinical trial: The ileal bile acid transporter inhibitor A3309 vs. placebo in patients with chronic idiopathic constipation--a double-blind study. elobixibat 69-74 solute carrier family 10 member 2 Homo sapiens 31-58 33278408-8 2021 Additionally, these uptakes were decreased by elobixibat, a selective ASBT inhibitor. elobixibat 46-56 solute carrier family 10 member 2 Homo sapiens 70-74 35626847-6 2022 Attempting to reduce the total bile acids, we initiated off-label use of the ileal bile acid transporter (IBAT) inhibitor Elobixibat (Goofice ), later converted to Odevixibat (Bylvay ). elobixibat 122-132 solute carrier family 10 member 2 Homo sapiens 77-104