PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
1587994-3	1992	Moreover, the SHR showed greater sensitivity to CCl4 stimulation in the sympathetic nervous system than the WKY, resulting in a decreased hepatic blood flow in the acute stage and a depleted CA in the adrenal gland, a lowered blood pressure (BP) and a released non-esterified fatty acid (NEFA) from peripheral adipose tissue in the chronic stage.	esterified	265-275	C-C motif chemokine ligand 4	Rattus norvegicus	48-52
2100741-3	1990	Removing the associated lipid from the perfusate albumin reduced the amount of non-esterified fatty acid (NEFA) transfer rather than enhanced it.	esterified	83-93	albumin	Cavia porcellus	49-56
28871187-9	2017	The underlying mechanism may depend on increased hepatic glycolytic flux due to increased pkm2 expression and consequent conversion of pyruvate to non-esterified fatty acid synthesis due to increased CS activity and ACLY levels.	esterified	151-161	citrate synthase	Rattus norvegicus	200-202
3084268-1	1986	A method for determination of reserve albumin equivalent for binding of warfarin as previously described [1] has been used for assessing the influence of non-esterified fatty acid concentration (NEFA) on binding of warfarin to human serum albumin (HSA).	esterified	158-168	albumin	Homo sapiens	233-246
28871187-9	2017	The underlying mechanism may depend on increased hepatic glycolytic flux due to increased pkm2 expression and consequent conversion of pyruvate to non-esterified fatty acid synthesis due to increased CS activity and ACLY levels.	esterified	151-161	ATP citrate lyase	Rattus norvegicus	216-220
26705406-11	2015	A fat tolerance test evidenced delayed plasma triglyceride clearance and greater transient availability of non-esterified fatty acids (NEFA) during the post-prandial state in the apoCIII mice plasma.	esterified	111-121	apolipoprotein C-III	Mus musculus	179-186
28440767-8	2017	In a univariate analysis, ZAG levels positively correlated to 24-h urinary free cortisol (p=0.001), body mass index (p=0.02), non-esterified fatty acids (p=0.05), glucose (p=0.003), LDL-C (p=0.028), and type 2 diabetes mellitus (p=0.016), and were inversely related to total adiponectin levels (p=0.035).	esterified	130-140	alpha-2-glycoprotein 1, zinc-binding	Homo sapiens	26-29
26853749-3	2016	Treatment with pharmacological doses of FGF21 acutely reduced plasma non-esterified fatty acids (NEFAs), liver TG content, and VLDL-TG secretion.	esterified	73-83	fibroblast growth factor 21	Mus musculus	40-45
26356502-3	2015	Of particular interest is the intertwined regulation of glucose and non-esterified fatty acids (NEFA), due to the association between disturbed NEFA metabolism and insulin resistance.	esterified	72-82	insulin	Homo sapiens	164-171
24204574-6	2013	The plasma levels of non-esterified fatty acids were significantly lower in the Herp(-/-); apoE(-/-) mice when they were eight and 16 weeks old.	esterified	25-35	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	Mus musculus	80-84
22738231-2	2012	As observed with many enzymes, Ypc1p can also catalyse the reverse reaction, i.e. condense a non-esterified fatty acid with PHS (phytosphingosine) or DHS (dihydrosphingosine) and thus synthesize ceramides.	esterified	97-107	phytoceramidase	Saccharomyces cerevisiae S288C	31-36
17291802-9	2007	In addition, it was observed that central administration of both VIP and PACAP induced a reduction in respiratory quotient and increased plasma non-esterified fatty acid concentrations.	esterified	148-158	vasoactive intestinal peptide	Gallus gallus	65-68
22944699-2	2012	The hydrolytic cleavage of triacylglycerol by adipose triglyceride lipase (ATGL) generates non-esterified fatty acids, which are subsequently used as essential precursors for lipid and membrane synthesis, mediators in cell signaling processes or as energy substrate in mitochondria.	esterified	95-105	patatin like phospholipase domain containing 2	Homo sapiens	46-73
22944699-2	2012	The hydrolytic cleavage of triacylglycerol by adipose triglyceride lipase (ATGL) generates non-esterified fatty acids, which are subsequently used as essential precursors for lipid and membrane synthesis, mediators in cell signaling processes or as energy substrate in mitochondria.	esterified	95-105	patatin like phospholipase domain containing 2	Homo sapiens	75-79
20460954-1	2011	BACKGROUND: Altered secretion of adipokines and non-esterified fatty acid (NEFA) seems to play a pivotal role in the abdominal obesity-related insulin resistance (IR).	esterified	52-62	insulin	Homo sapiens	143-150
17291802-9	2007	In addition, it was observed that central administration of both VIP and PACAP induced a reduction in respiratory quotient and increased plasma non-esterified fatty acid concentrations.	esterified	148-158	adenylate cyclase activating polypeptide 1	Gallus gallus	73-78
15684343-5	2005	Administration of PRL resulted in an acute increase in colonic temperature in conjunction with increased plasma concentrations of non-esterified fatty acids and, as a result, the normal postnatal decline in body temperature was delayed.	esterified	134-144	prolactin	Ovis aries	18-21
11728630-1	2001	Phosphoenolpyruvate carboxykinase (PEPCK) is the key enzyme in glyceroneogenesis, an important metabolic pathway that functions to restrain the release of non-esterified fatty acids (NEFAs) from adipocytes.	esterified	159-169	phosphoenolpyruvate carboxykinase 2, mitochondrial	Homo sapiens	0-33
11728630-1	2001	Phosphoenolpyruvate carboxykinase (PEPCK) is the key enzyme in glyceroneogenesis, an important metabolic pathway that functions to restrain the release of non-esterified fatty acids (NEFAs) from adipocytes.	esterified	159-169	phosphoenolpyruvate carboxykinase 2, mitochondrial	Homo sapiens	35-40
11589678-1	2001	OBJECTIVE: High non-esterified fatty acid (NEFA) levels impair glucose-stimulated insulin secretion from islets derived from non-diabetic Zucker rats that are genetically predisposed to diabetes.	esterified	20-30	insulin	Homo sapiens	82-89
10952470-2	2000	It is hypothesised that the primary route by which insulin maintains control over glucose production is indirect and is mediated by regulation of non-esterified fatty acid release from the adipocyte.	esterified	150-160	insulin	Canis lupus familiaris	51-58
10768092-7	2000	Hepatic lipase-mediated non-esterified fatty acid release from HDL lipids was enhanced in glycated HDL compared with control HDL (25 +/- 1 vs 16 +/- 1 nmol non-esterified fatty acid hydrolysed/min, respectively, p < 0.0001).	esterified	28-38	lipase C, hepatic type	Homo sapiens	0-14
9566856-7	1998	We conclude that abdominal obesity is associated with a higher resistance to insulin mediated suppression of non-esterified fatty acids in obese subjects.	esterified	113-123	insulin	Homo sapiens	77-84
8582538-1	1995	Our study investigates short- and long-term effects of infusion of non-esterified fatty acids (NEFA) on insulin secretion in healthy subjects.	esterified	71-81	insulin	Homo sapiens	104-111
7867881-2	1994	Fed GLUT 4 transgenic mice exhibited a 32% and 56% reduction in serum glucose and insulin and a 69% and 33% increase in non-esterified fatty acid and lactate levels, respectively.	esterified	124-134	solute carrier family 2 (facilitated glucose transporter), member 4	Mus musculus	4-10
8243878-7	1993	The present results demonstrate that insulin-like growth factor I is capable of mimicking the acute effects of insulin on metabolic substrates (plasma glucose, non-esterified fatty acids, leucine).	esterified	164-174	insulin like growth factor 1	Homo sapiens	37-65
8243878-7	1993	The present results demonstrate that insulin-like growth factor I is capable of mimicking the acute effects of insulin on metabolic substrates (plasma glucose, non-esterified fatty acids, leucine).	esterified	164-174	insulin	Homo sapiens	37-44