PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
34769192-0	2021	Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-beta1: Induction of Cystathionine gamma-Lyase and Cystathionine beta-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways.	reactive sulfur species	13-36	transforming growth factor beta 1	Bos taurus	94-103
34748908-0	2021	Rhodanese Rdl2 produces reactive sulfur species to protect mitochondria from reactive oxygen species.	reactive sulfur species	24-47	thiosulfate sulfurtransferase RDL2	Saccharomyces cerevisiae S288C	10-14
34769192-0	2021	Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-beta1: Induction of Cystathionine gamma-Lyase and Cystathionine beta-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways.	reactive sulfur species	13-36	cystathionine gamma-lyase	Bos taurus	118-143
34769192-0	2021	Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-beta1: Induction of Cystathionine gamma-Lyase and Cystathionine beta-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways.	reactive sulfur species	13-36	cystathionine beta-synthase	Bos taurus	148-175
34769192-0	2021	Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-beta1: Induction of Cystathionine gamma-Lyase and Cystathionine beta-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways.	reactive sulfur species	13-36	SMAD family member 2	Bos taurus	208-217
34769192-0	2021	Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-beta1: Induction of Cystathionine gamma-Lyase and Cystathionine beta-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways.	reactive sulfur species	13-36	SMAD family member 2	Bos taurus	227-234
34769192-0	2021	Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-beta1: Induction of Cystathionine gamma-Lyase and Cystathionine beta-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways.	reactive sulfur species	13-36	activating transcription factor 4	Bos taurus	235-239
31436417-12	2019	Reactive sulfur species are thus likely unrecognized immune-mediators with potential as therapeutic agents through these interactions with IDO1.	reactive sulfur species	0-23	indoleamine 2,3-dioxygenase 1	Homo sapiens	139-143
30187770-0	2019	Reactive Sulfur Species Emerge as Gliotransmitters to Support Memory via Sulfuration-Dependent Gating of NR2A-Containing N-Methyl-d-Aspartate Subtype Glutamate Receptor Function.	reactive sulfur species	0-23	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	105-109
30415410-3	2019	Here, we address how reactive sulfur species-the gaseous messenger H2S and polysulfides-affect N-type inactivation of the mammalian Kv channels Kv1.4 and Kv3.4.	reactive sulfur species	21-44	potassium voltage-gated channel subfamily A member 4	Homo sapiens	144-149
30415410-3	2019	Here, we address how reactive sulfur species-the gaseous messenger H2S and polysulfides-affect N-type inactivation of the mammalian Kv channels Kv1.4 and Kv3.4.	reactive sulfur species	21-44	potassium voltage-gated channel subfamily C member 4	Homo sapiens	154-159
30509490-0	2019	Reactive sulfur species impair Ca2+/calmodulin-dependent protein kinase II via polysulfidation.	reactive sulfur species	0-23	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	31-74
30509490-2	2019	Herein, we show that polysulfidation of CaMKII at Cys6 limits its enzyme activity following reactive sulfur species (RSS) stimulus.	reactive sulfur species	92-115	calcium/calmodulin dependent protein kinase II gamma	Homo sapiens	40-46
30394289-1	2019	We have recently reported that Ca2+/calmodulin (CaM)-dependent protein kinase IV (CaMKIV) is inactivated by reactive sulfur species via polysulfidation of the active-site Cys residue.	reactive sulfur species	108-131	calcium/calmodulin dependent protein kinase IV	Homo sapiens	82-88
31527361-0	2019	[Development of fluorescent probes for detecting reactive sulfur species and their application to development of inhibitors for 3MST].	reactive sulfur species	49-72	mercaptopyruvate sulfurtransferase	Homo sapiens	129-132
28115653-2	2017	The current consensus is that reactive persulfides and polysulfides produced by cystathionine gamma-lyase (CSE) and cystathionine beta-synthase are highly nucleophilic and thus cadmium may be captured by these reactive sulfur species.	reactive sulfur species	210-233	cystathionine gamma-lyase	Bos taurus	80-105
28115653-2	2017	The current consensus is that reactive persulfides and polysulfides produced by cystathionine gamma-lyase (CSE) and cystathionine beta-synthase are highly nucleophilic and thus cadmium may be captured by these reactive sulfur species.	reactive sulfur species	210-233	cystathionine gamma-lyase	Bos taurus	107-110
28115653-2	2017	The current consensus is that reactive persulfides and polysulfides produced by cystathionine gamma-lyase (CSE) and cystathionine beta-synthase are highly nucleophilic and thus cadmium may be captured by these reactive sulfur species.	reactive sulfur species	210-233	cystathionine beta-synthase	Bos taurus	116-143
28115653-7	2017	The knockdown of CSE and/or cystathionine beta-synthase decreased the levels of reactive sulfur species in the cells and increased the degree of HSP70 induction and cytotoxicity caused by exposure to cadmium.	reactive sulfur species	80-103	cystathionine gamma-lyase	Bos taurus	17-20
28115653-7	2017	The knockdown of CSE and/or cystathionine beta-synthase decreased the levels of reactive sulfur species in the cells and increased the degree of HSP70 induction and cytotoxicity caused by exposure to cadmium.	reactive sulfur species	80-103	cystathionine beta-synthase	Bos taurus	28-55
25807370-0	2015	Reactive Sulfur Species-Mediated Activation of the Keap1-Nrf2 Pathway by 1,2-Naphthoquinone through Sulfenic Acids Formation under Oxidative Stress.	reactive sulfur species	0-23	kelch like ECH associated protein 1	Homo sapiens	51-56
25807370-0	2015	Reactive Sulfur Species-Mediated Activation of the Keap1-Nrf2 Pathway by 1,2-Naphthoquinone through Sulfenic Acids Formation under Oxidative Stress.	reactive sulfur species	0-23	NFE2 like bZIP transcription factor 2	Homo sapiens	57-61
25452233-4	2014	We also found that hydrogen sulfide-related reactive sulfur species (RSS) function as potent nucleophiles to eliminate electrophilic modification of H-Ras and suppress the onset of chronic heart failure after myocardial infarction.	reactive sulfur species	44-67	HRas proto-oncogene, GTPase	Homo sapiens	149-154
33641584-0	2021	Reactive sulfur species inhibit the migration of PDGF-treated vascular smooth muscle cells by blocking the reactive oxygen species-regulated Akt signaling pathway.	reactive sulfur species	0-23	AKT serine/threonine kinase 1	Homo sapiens	141-144
31952233-3	2020	This review focuses on Nrf2 activation and its involvement with the protective defense systems under electrophilic stresses integrated with our recent findings that reactive sulfur species (RSS) mediate detoxification of electrophiles.	reactive sulfur species	165-188	NFE2 like bZIP transcription factor 2	Homo sapiens	23-27
31166132-2	2019	We found that reactive sulfur species (RSS), such as cysteine persulfides produced by cystathionine [Formula: see text] (CSE), capture environmental electrophiles through formation of sulfur adducts.	reactive sulfur species	14-37	cystathionase (cystathionine gamma-lyase)	Mus musculus	121-124
30790656-2	2019	ROS are chemically and functionally similar to reactive sulfur species (RSS) and both ROS and RSS have been shown to be metabolized by the antioxidant enzymes, superoxide dismutase and catalase.	reactive sulfur species	47-70	catalase	Homo sapiens	185-193
29220697-0	2018	Metabolism of hydrogen sulfide (H2S) and Production of Reactive Sulfur Species (RSS) by superoxide dismutase.	reactive sulfur species	55-78	superoxide dismutase 1	Homo sapiens	88-108