PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 33859711-7 2021 GGDE reduced the levels of IgE, TNF-alpha, IL-13, eotaxin, and VEGF and mast cell/eosinophil infiltration and prevented the decreases in the levels of involucrin and loricrin in the skin. ggde 0-4 tumor necrosis factor Mus musculus 32-41 33859711-11 2021 In the TNF-alpha/IFN-gamma- (TI-) stimulated HaCaT cells, GGDE decreased the thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) production significantly by inhibiting p-STAT1 and NF-kappaB signaling. ggde 58-62 tumor necrosis factor Homo sapiens 7-16 33859711-7 2021 GGDE reduced the levels of IgE, TNF-alpha, IL-13, eotaxin, and VEGF and mast cell/eosinophil infiltration and prevented the decreases in the levels of involucrin and loricrin in the skin. ggde 0-4 interleukin 13 Mus musculus 43-48 33859711-11 2021 In the TNF-alpha/IFN-gamma- (TI-) stimulated HaCaT cells, GGDE decreased the thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) production significantly by inhibiting p-STAT1 and NF-kappaB signaling. ggde 58-62 interferon gamma Homo sapiens 17-26 33859711-7 2021 GGDE reduced the levels of IgE, TNF-alpha, IL-13, eotaxin, and VEGF and mast cell/eosinophil infiltration and prevented the decreases in the levels of involucrin and loricrin in the skin. ggde 0-4 chemokine (C-C motif) ligand 11 Mus musculus 50-57 33859711-11 2021 In the TNF-alpha/IFN-gamma- (TI-) stimulated HaCaT cells, GGDE decreased the thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) production significantly by inhibiting p-STAT1 and NF-kappaB signaling. ggde 58-62 C-C motif chemokine ligand 17 Homo sapiens 77-118 33859711-11 2021 In the TNF-alpha/IFN-gamma- (TI-) stimulated HaCaT cells, GGDE decreased the thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) production significantly by inhibiting p-STAT1 and NF-kappaB signaling. ggde 58-62 C-C motif chemokine ligand 17 Homo sapiens 120-124 33859711-7 2021 GGDE reduced the levels of IgE, TNF-alpha, IL-13, eotaxin, and VEGF and mast cell/eosinophil infiltration and prevented the decreases in the levels of involucrin and loricrin in the skin. ggde 0-4 vascular endothelial growth factor A Mus musculus 63-67 33859711-11 2021 In the TNF-alpha/IFN-gamma- (TI-) stimulated HaCaT cells, GGDE decreased the thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) production significantly by inhibiting p-STAT1 and NF-kappaB signaling. ggde 58-62 C-C motif chemokine ligand 22 Homo sapiens 130-158 33859711-11 2021 In the TNF-alpha/IFN-gamma- (TI-) stimulated HaCaT cells, GGDE decreased the thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) production significantly by inhibiting p-STAT1 and NF-kappaB signaling. ggde 58-62 C-C motif chemokine ligand 22 Homo sapiens 160-163 33859711-7 2021 GGDE reduced the levels of IgE, TNF-alpha, IL-13, eotaxin, and VEGF and mast cell/eosinophil infiltration and prevented the decreases in the levels of involucrin and loricrin in the skin. ggde 0-4 loricrin Mus musculus 166-174 33859711-8 2021 GGDE also suppressed the SI-induced increases in corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH), and corticosterone (CORT) in socially isolated AD mice. ggde 0-4 corticotropin releasing hormone Mus musculus 49-80 33859711-11 2021 In the TNF-alpha/IFN-gamma- (TI-) stimulated HaCaT cells, GGDE decreased the thymus and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC) production significantly by inhibiting p-STAT1 and NF-kappaB signaling. ggde 58-62 signal transducer and activator of transcription 1 Homo sapiens 206-211 33859711-12 2021 GGDE also reduced VEGF production in HMC-1 cells stimulated with CRH/substance P (SP) by inhibiting p-ERK signaling pathway. ggde 0-4 vascular endothelial growth factor A Homo sapiens 18-22 33859711-8 2021 GGDE also suppressed the SI-induced increases in corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH), and corticosterone (CORT) in socially isolated AD mice. ggde 0-4 corticotropin releasing hormone Mus musculus 82-85 33859711-12 2021 GGDE also reduced VEGF production in HMC-1 cells stimulated with CRH/substance P (SP) by inhibiting p-ERK signaling pathway. ggde 0-4 corticotropin releasing hormone Homo sapiens 65-68 33859711-8 2021 GGDE also suppressed the SI-induced increases in corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH), and corticosterone (CORT) in socially isolated AD mice. ggde 0-4 pro-opiomelanocortin-alpha Mus musculus 88-115 33859711-14 2021 Moreover, GGDE suppressed the LPS-induced production of NO, TNF-alpha, IL-1beta, and IL-6 in BV2 cells. ggde 10-14 tumor necrosis factor Mus musculus 60-69 33859711-14 2021 Moreover, GGDE suppressed the LPS-induced production of NO, TNF-alpha, IL-1beta, and IL-6 in BV2 cells. ggde 10-14 interleukin 1 alpha Mus musculus 71-79 33859711-8 2021 GGDE also suppressed the SI-induced increases in corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH), and corticosterone (CORT) in socially isolated AD mice. ggde 0-4 pro-opiomelanocortin-alpha Mus musculus 117-121 33859711-14 2021 Moreover, GGDE suppressed the LPS-induced production of NO, TNF-alpha, IL-1beta, and IL-6 in BV2 cells. ggde 10-14 interleukin 6 Mus musculus 85-89