PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21790190-3	2011	MeSA reduced CI and enhanced the accumulation of putrescine, spermidine, and spermine, which was associated with increased gene expression levels and activities of arginase, arginine decarboxylase, and ornithine decarboxylase at most sampling times.	methyl salicylate	0-4	arginine decarboxylase	Solanum lycopersicum	174-196
24973956-5	2014	Surprisingly, the MeSA biosynthesis mutant bsmt1-1 treated with egg extract was still repellent to butterflies when compared to untreated bsmt1-1.	methyl salicylate	18-22	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	43-48
22749315-2	2012	Several candidates for this long-distance signal have been identified, including methyl salicylate (MeSA), an SFD1/GLY1-derived glycerol-3-phosphate (G3P)-dependent signal, the lipid-transfer protein DIR1, the dicarboxylic acid azelaic acid (AzA), the abietane diterpenoid dehydroabietinal (DA), jasmonic acid (JA), and the amino acid-derivative pipecolic acid (Pip).	methyl salicylate	100-104	FKBP prolyl isomerase like	Homo sapiens	200-204
22476973-8	2012	For methyl salicylate and capsaicin, drug diffusion in the PSA matrices is the main factor controlled by the release kinetic constant k. The high [SI] diblock content and high plasticizer amount in matrix provide the PSA with a homogeneous and soften microstructure, resulting in a high diffusion rate.	methyl salicylate	4-21	aminopeptidase puromycin sensitive	Homo sapiens	59-62
22476973-8	2012	For methyl salicylate and capsaicin, drug diffusion in the PSA matrices is the main factor controlled by the release kinetic constant k. The high [SI] diblock content and high plasticizer amount in matrix provide the PSA with a homogeneous and soften microstructure, resulting in a high diffusion rate.	methyl salicylate	4-21	aminopeptidase puromycin sensitive	Homo sapiens	217-220
21790190-3	2011	MeSA reduced CI and enhanced the accumulation of putrescine, spermidine, and spermine, which was associated with increased gene expression levels and activities of arginase, arginine decarboxylase, and ornithine decarboxylase at most sampling times.	methyl salicylate	0-4	ornithine decarboxylase	Solanum lycopersicum	202-225
20687805-3	2010	Once in the distal, uninfected tissue of these plant species, MeSA must be converted into biologically active SA by the esterase activity of SA-binding protein 2 (SABP2) in tobacco or members of the AtMES family in Arabidopsis.	methyl salicylate	62-66	salicylic acid-binding protein 2	Nicotiana tabacum	141-161
20687805-3	2010	Once in the distal, uninfected tissue of these plant species, MeSA must be converted into biologically active SA by the esterase activity of SA-binding protein 2 (SABP2) in tobacco or members of the AtMES family in Arabidopsis.	methyl salicylate	62-66	salicylic acid-binding protein 2	Nicotiana tabacum	163-168
20687805-4	2010	In this study, we have identified the potato ortholog of tobacco SABP2 (StMES1) and shown that the recombinant protein converts MeSA to SA; this MeSA esterase activity is feedback inhibited by SA or its synthetic analog, 2, 2, 2, 2"-tetra-fluoroacetophenone (tetraFA).	methyl salicylate	128-132	salicylic acid-binding protein 2	Nicotiana tabacum	65-70
20488836-5	2010	The genes BSMT1 and Cyp72A13 could be connected to the emission of methyl salicylate and (E,E)-4,8,12-trimethyltrideca-1,3,7,11-tetraene (TMTT), respectively.	methyl salicylate	67-84	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	10-15
20488836-5	2010	The genes BSMT1 and Cyp72A13 could be connected to the emission of methyl salicylate and (E,E)-4,8,12-trimethyltrideca-1,3,7,11-tetraene (TMTT), respectively.	methyl salicylate	67-84	cytochrome P450, family 72, subfamily A, polypeptide 13	Arabidopsis thaliana	20-28
20407809-4	2010	Pieris rapae infested AtBSMT1-KO mutant Arabidopsis plants, compromised in the biosynthesis of MeSA, were more attractive to parasitoids than infested wild-type plants.	methyl salicylate	95-99	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	22-29
20407809-6	2010	Furthermore, in line with this, we recorded a positive correlation between MeSA dose and repellence of D. semiclausum when supplementing the headspace of caterpillar-infested AtBSMT1-KO plants with synthetic MeSA.	methyl salicylate	75-79	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	175-182
18643994-3	2008	Of 14 recombinant AtMES (MES for methyl esterase) proteins tested, five showed preference for MeSA as a substrate and displayed SA inhibition of MeSA esterase activity in vitro (AtMES1, -2, -4, -7, and -9).	methyl salicylate	94-98	methylesterase	Arabidopsis thaliana	33-48
20070566-9	2010	The higher MeSA emissions associate with significantly higher SpSAMT expression, consistent with SAMT gene expression being rate limiting for ripening-associated MeSA emissions.	methyl salicylate	11-15	salicylic acid methyltransferase	Solanum lycopersicum	64-68
20070566-13	2010	Taken together, the results indicate that SlSAMT is critical for methyl salicylate synthesis and methyl salicylate, in turn, likely has an important role in controlling SA synthesis.	methyl salicylate	65-82	salicylic acid methyltransferase	Solanum lycopersicum	42-48
19669626-5	2009	A T-DNA insertion mutation in the AtBSMT1 resulted in reduced methyl salicylate (MeSA) levels upon P. syringae infection.	methyl salicylate	62-79	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	34-41
19669626-5	2009	A T-DNA insertion mutation in the AtBSMT1 resulted in reduced methyl salicylate (MeSA) levels upon P. syringae infection.	methyl salicylate	81-85	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	34-41
19958141-4	2010	A knockout mutant (Atbsmt1) failed to accumulate MeSA following pathogen infection; these plants also failed to accumulate SA or its glucoside in the uninoculated leaves and did not develop systemic acquired resistance (SAR).	methyl salicylate	49-53	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	19-26
19958141-6	2010	Analyses of transgenic Arabidopsis plants overexpressing AtBSMT1 revealed that they accumulate elevated levels of MeSA in pathogen-infected leaves but fail to develop SAR.	methyl salicylate	114-118	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	57-64
19958141-7	2010	Since the levels of SA and its glucoside were reduced in uninoculated systemic leaves of these plants whereas MeSA levels were elevated, AtBSMT1-mediated conversion of SA to MeSA probably compromised SAR development by suppressing SA accumulation in uninoculated leaves.	methyl salicylate	110-114	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	137-144
19958141-7	2010	Since the levels of SA and its glucoside were reduced in uninoculated systemic leaves of these plants whereas MeSA levels were elevated, AtBSMT1-mediated conversion of SA to MeSA probably compromised SAR development by suppressing SA accumulation in uninoculated leaves.	methyl salicylate	174-178	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	137-144
18643994-6	2008	Underexpression by knockout mutation and/or RNAi-mediated silencing of multiple AtMES genes, including AtMES1, -2, -7, and -9, compromised SAR in Arabidopsis and correlated with enhanced accumulation of MeSA in the systemic tissue of SAR-induced plants.	methyl salicylate	203-207	methyl esterase 1	Arabidopsis thaliana	103-109
17916738-2	2007	By stimulating immune responses in mosaic tobacco plants created by grafting different genetic backgrounds, we showed that the methyl salicylate (MeSA) esterase activity of salicylic acid-binding protein 2 (SABP2), which converts MeSA into salicylic acid (SA), is required for SAR signal perception in systemic tissue, the tissue that does not receive the primary (initial) infection.	methyl salicylate	146-150	salicylic acid-binding protein 2	Nicotiana tabacum	207-212
18467465-4	2008	Recently, it has been shown that the tobacco (Nicotiana tabacum) protein SABP2 (salicylic acid binding protein 2) hydrolyzes methyl salicylate to salicylic acid.	methyl salicylate	125-142	salicylic acid-binding protein 2	Nicotiana tabacum	73-78
18467465-4	2008	Recently, it has been shown that the tobacco (Nicotiana tabacum) protein SABP2 (salicylic acid binding protein 2) hydrolyzes methyl salicylate to salicylic acid.	methyl salicylate	125-142	salicylic acid-binding protein 2	Nicotiana tabacum	80-112
18226820-4	2008	On the other hand, the overexpression increased the levels of methyl salicylate (MeSA) and methyl salicylate 2-O-beta-D-glucoside (MeSAG), and also induced SA carboxyl methyltransferase1 (AtBSMT1) expression, whose products catalyze the conversion of SA to MeSA.	methyl salicylate	62-79	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	188-195
18226820-5	2008	Our data indicate that reduced resistance by AtSGT1 overexpression results from a reduction in SA content, which is at least in part caused by increases in MeSAG and MeSA levels at the expense of SA.	methyl salicylate	156-160	UDP-glucosyltransferase 74F2	Arabidopsis thaliana	45-51
17916738-3	2007	Moreover, in plants expressing mutant SABP2 with unregulated MeSA esterase activity in SAR signal-generating, primary infected leaves, SAR was compromised and the associated increase in MeSA levels was suppressed in primary infected leaves, their phloem exudates, and systemic leaves.	methyl salicylate	61-65	salicylic acid-binding protein 2	Nicotiana tabacum	38-43
17404454-12	2007	After ethanol fixation, the RFP and GFP fluorescence proved remarkably robust to subsequent exposure to either methyl salicylate or BABB.	methyl salicylate	111-128	tripartite motif containing 27	Homo sapiens	28-31
17566109-3	2007	Here, we report that PDF1.2, PR-1 (pathogenesis protein), and PROPEP genes were differentially expressed in the leaves of intact plants sprayed with methyl jasmonate and methyl salicylate and in excised leaves supplied through cut petioles with peptides derived from the C terminus of each of the encoded proteins.	methyl salicylate	170-187	plant defensin 1.2	Arabidopsis thaliana	21-27
17404454-13	2007	The optimized optical clearing procedure of ethanol fixation followed by methyl salicylate clearing preserved the fluorescence of constitutive RFP in whole xenograft tumour specimens, about 1 cc in dimension, indicating successful extension from cell plating experiments to whole tissue samples.	methyl salicylate	73-90	tripartite motif containing 27	Homo sapiens	143-146
17364628-27	2007	9) For patients with an ocular exposure of methyl salicylate or salicylic acid, the eye(s) should be irrigated with room-temperature tap water for 15 minutes.	methyl salicylate	43-60	nuclear RNA export factor 1	Homo sapiens	133-136
15599762-5	2005	While headspace VOC analysis showed an increase in (Z)-3-hexenyl acetate and methyl salicylate with lox and pal induction, respectively, MPI accumulation was not observed with an increase in mpi transcripts.	methyl salicylate	77-94	linoleate 9S-lipoxygenase1	Zea mays	100-103
16719518-4	2006	Geraniol, linalool, methyl salicylate, benzyl alcohol, and 2-phenylethanol exhibited significant antifungal activities toward Colletorichum camelliae Massea, although cis-3-hexenol and linalool oxides showed weaker activities by comparison.	methyl salicylate	20-37	suppressor of cytokine signaling 3	Homo sapiens	167-172
33106972-10	2020	We did however see evidence for residual priming, as plants treated with MeSA and infested with whiteflies produced significantly higher levels of POD activity than whitefly infestation alone.	methyl salicylate	73-77	peroxidase	Solanum lycopersicum	147-150
9429234-10	1997	Furthermore, UGT1A6*2 metabolized 3-O-methyl-dopa and methyl salicylate at 41-74% of that of the wild-type, and a series of beta-blockers at 28-69% of the normal level.	methyl salicylate	54-71	UDP glucuronosyltransferase family 1 member A6	Homo sapiens	13-19
34715565-12	2021	Although more research is needed before industrial application, it is concluded that methyl salicylate can be used to improve beta-carotene contents in chia sprouts.	methyl salicylate	85-102	chitinase acidic	Homo sapiens	152-156
34512679-5	2021	Wounding did not activate the LeDES promoter, but auxins and methyl salicylate triggered LeDES expression, indicating a hormone-mediated function of DVEs.	methyl salicylate	61-78	9-divinyl ether synthase	Solanum lycopersicum	89-94
34512679-9	2021	Taken together, our results suggest an important role for LeDES as a determinant in the defense response during M. javanica parasitism, and indicate two functional modes: directly via DVE motility inhibition effect and through signal molecule-mediated defense reactions to nematodes that depend on methyl salicylate.	methyl salicylate	298-315	9-divinyl ether synthase	Solanum lycopersicum	58-63
35430419-1	2022	The insect repellent methyl salicylate elicits excitatory responses upon interaction with CquiOR32, an odorant receptor (OR) from the southern house mosquito, Culex quinquefasciatus.	methyl salicylate	21-38	putative odorant receptor 83c	Culex quinquefasciatus	103-119
35430419-1	2022	The insect repellent methyl salicylate elicits excitatory responses upon interaction with CquiOR32, an odorant receptor (OR) from the southern house mosquito, Culex quinquefasciatus.	methyl salicylate	21-38	putative odorant receptor 83c	Culex quinquefasciatus	121-123
15668381-6	2005	Our biochemical studies reveal that SABP2 has strong esterase activity with methyl salicylate as the substrate, and that SA is a potent product inhibitor of this catalysis.	methyl salicylate	76-93	salicylic acid-binding protein 2	Nicotiana tabacum	36-41
11941466-9	2002	The accumulation of cat1 mRNA was increased substantially by MeJA, while it was reduced by MeSA treatment.	methyl salicylate	91-95	catalase isozyme 1	Solanum lycopersicum	20-24
32629175-8	2021	Further, treatment with the TRPA1 inhibitors TCS-5861528 (1muM) or AP-18 (1muM) blocked the methyl salicylate-induced protective effect in isolated adult cardiomyocytes.	methyl salicylate	92-109	transient receptor potential cation channel, subfamily A, member 1	Rattus norvegicus	28-33
32899966-6	2020	Overall, it could be concluded that MeSa treatment at 0.1 mM could be the most useful tool to increase bioactive compounds with antioxidant properties in table grape and in turn, their health beneficial properties, with additional effects on increasing crop yield, accelerating on-vine ripening process and maintaining quality traits during prolonged storage.	methyl salicylate	36-40	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	253-257
32582454-1	2020	A series of methyl salicylate (MeSA)/beta-cyclodextrin (beta-CD) inclusion complexes (ICs) were prepared at different MeSA concentrations by the co-precipitation method using methyl salicylate for maintaining the quality of fresh produce.	methyl salicylate	12-29	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	56-63
32582454-1	2020	A series of methyl salicylate (MeSA)/beta-cyclodextrin (beta-CD) inclusion complexes (ICs) were prepared at different MeSA concentrations by the co-precipitation method using methyl salicylate for maintaining the quality of fresh produce.	methyl salicylate	175-192	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	56-63
32582454-5	2020	In addition, the MeSA release from ICs of all grades followed a diffusive nature and first-order kinetics at 25  C under all RH conditions, except at 7  C. These results indicate that the use of a MeSA/beta-CD IC in active packaging applications can effective maintain the quality of fresh produce.	methyl salicylate	17-21	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	202-209
30847000-3	2019	In plants, SA binding protein 2 (SABP2), possessing methyl salicylate (MeSA) esterase activity, catalyzes the conversion of MeSA to SA.	methyl salicylate	71-75	salicylic acid-binding protein 2	Nicotiana tabacum	11-31
31690562-4	2020	In a forward genetic screen for C. elegans mutants with defective avoidance response to the plant hormone methyl salicylate (MeSa), we isolated multiple loss-of-function mutations in unc-80 and unc-79 C. elegans NALCN mutants exhibited similarly defective MeSa avoidance.	methyl salicylate	106-130	Protein unc-80	Caenorhabditis elegans	183-189
31690562-4	2020	In a forward genetic screen for C. elegans mutants with defective avoidance response to the plant hormone methyl salicylate (MeSa), we isolated multiple loss-of-function mutations in unc-80 and unc-79 C. elegans NALCN mutants exhibited similarly defective MeSa avoidance.	methyl salicylate	106-130	Uncoordinated protein 79	Caenorhabditis elegans	194-200
31283020-5	2019	The largest effects were obtained with 100, 50 muM, and 40 mM for MeSA, MeJA, and GABA, respectively, which enhanced the activity of the antioxidant enzymes catalase (CAT), ascorbate peroxidase (APX) and superoxide dismutase (SOD), and phenylalanine ammonia-lyase (PAL).	methyl salicylate	66-70	catalase	Homo sapiens	157-165
31283020-5	2019	The largest effects were obtained with 100, 50 muM, and 40 mM for MeSA, MeJA, and GABA, respectively, which enhanced the activity of the antioxidant enzymes catalase (CAT), ascorbate peroxidase (APX) and superoxide dismutase (SOD), and phenylalanine ammonia-lyase (PAL).	methyl salicylate	66-70	catalase	Homo sapiens	167-170
30962291-6	2019	Biochemical analysis indicated that UGT71C3 exhibited strong enzymatic activity toward MeSA to form MeSA glucosides in vitro and in vivo.	methyl salicylate	87-91	UDP-glucosyl transferase 71C3	Arabidopsis thaliana	36-43
30962291-8	2019	In agreement, after primary infection of local leaves, ugt71c3 knockout mutants accumulated significantly more systemic MeSA and SA than that in wild-type plants.	methyl salicylate	120-124	UDP-glucosyl transferase 71C3	Arabidopsis thaliana	55-62
30962291-10	2019	Our results suggest that MeSA glucosylation by UGT71C3 facilitates negative regulation of the SAR response by modulating homeostasis of MeSA and SA.	methyl salicylate	25-29	UDP-glucosyl transferase 71C3	Arabidopsis thaliana	47-54
30962291-10	2019	Our results suggest that MeSA glucosylation by UGT71C3 facilitates negative regulation of the SAR response by modulating homeostasis of MeSA and SA.	methyl salicylate	136-140	UDP-glucosyl transferase 71C3	Arabidopsis thaliana	47-54
30846791-3	2019	In many plant species, conversion of MeSA into SA is mediated by MeSA esterases of the SABP2 family.	methyl salicylate	37-41	salicylic acid-binding protein 2	Nicotiana tabacum	87-92
30846791-4	2019	Here we show that the Citrus sinensis SABP2 homologue protein CsMES1 catalyzes the hydrolysis of MeSA into SA.	methyl salicylate	97-101	salicylic acid-binding protein 2	Nicotiana tabacum	38-43
30847000-3	2019	In plants, SA binding protein 2 (SABP2), possessing methyl salicylate (MeSA) esterase activity, catalyzes the conversion of MeSA to SA.	methyl salicylate	71-75	salicylic acid-binding protein 2	Nicotiana tabacum	33-38
25527285-0	2015	Neuropeptide receptors NPR-1 and NPR-2 regulate Caenorhabditis elegans avoidance response to the plant stress hormone methyl salicylate.	methyl salicylate	118-135	G_PROTEIN_RECEP_F1_2 domain-containing protein	Caenorhabditis elegans	23-28
28946463-7	2018	It was demonstrated that lipase is able to hydrolyse AME to methyl 2-hydroxy benzoate (methyl salicylate), which applications include fragrance agents in food, beverages and cosmetics, or analgesic agent in liniments.	methyl salicylate	60-85	PAN0_003d1715	Moesziomyces antarcticus	25-31
28946463-7	2018	It was demonstrated that lipase is able to hydrolyse AME to methyl 2-hydroxy benzoate (methyl salicylate), which applications include fragrance agents in food, beverages and cosmetics, or analgesic agent in liniments.	methyl salicylate	87-104	PAN0_003d1715	Moesziomyces antarcticus	25-31
28535671-3	2017	Treatment with Arg + MeSA not only enhanced the activities of superoxide dismutase, catalase, and peroxidase but also promoted the expression levels of pathogenesis-related protein 1 gene and the activities of defense-related enzymes of phenylalanine ammonia-lyase, polyphenol oxidase, beta-1,3-glucanase, and chitinase during most of the storage periods, which were associated with lower disease incidence and disease index.	methyl salicylate	21-25	catalase isozyme 1	Solanum lycopersicum	84-92
28535671-3	2017	Treatment with Arg + MeSA not only enhanced the activities of superoxide dismutase, catalase, and peroxidase but also promoted the expression levels of pathogenesis-related protein 1 gene and the activities of defense-related enzymes of phenylalanine ammonia-lyase, polyphenol oxidase, beta-1,3-glucanase, and chitinase during most of the storage periods, which were associated with lower disease incidence and disease index.	methyl salicylate	21-25	peroxidase	Solanum lycopersicum	98-108
28535671-3	2017	Treatment with Arg + MeSA not only enhanced the activities of superoxide dismutase, catalase, and peroxidase but also promoted the expression levels of pathogenesis-related protein 1 gene and the activities of defense-related enzymes of phenylalanine ammonia-lyase, polyphenol oxidase, beta-1,3-glucanase, and chitinase during most of the storage periods, which were associated with lower disease incidence and disease index.	methyl salicylate	21-25	phenylalanine ammonia-lyase	Solanum lycopersicum	237-264
28535671-3	2017	Treatment with Arg + MeSA not only enhanced the activities of superoxide dismutase, catalase, and peroxidase but also promoted the expression levels of pathogenesis-related protein 1 gene and the activities of defense-related enzymes of phenylalanine ammonia-lyase, polyphenol oxidase, beta-1,3-glucanase, and chitinase during most of the storage periods, which were associated with lower disease incidence and disease index.	methyl salicylate	21-25	glucan endo-1,3-beta-glucosidase B	Solanum lycopersicum	286-304
28860658-6	2017	Conversion of acetophenone to methyl salicylate was observed in the medium of CYP1a2-expressing cells.	methyl salicylate	30-47	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	78-84
28860658-7	2017	MOR161-2-expressing cells exhibited significantly greater responses to methyl salicylate than to acetophenone.	methyl salicylate	71-88	olfactory receptor family 8 subfamily B member 12	Mus musculus	0-8
28860658-9	2017	MOR161-2 responded to both acetophenone and methyl salicylate in vivo.	methyl salicylate	44-61	olfactory receptor family 8 subfamily B member 12	Mus musculus	0-8
28860658-11	2017	Our data suggest that CYP1a2 affects OR activation by converting acetophenone to methyl salicylate.	methyl salicylate	81-98	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	22-28
27123900-2	2016	With the goal of enhancing potency and selectivity of the PTP1B inhibitors, a series of methyl salicylate derivatives as ABC type PTP1B inhibitors (P1-P7) were discovered.	methyl salicylate	88-105	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	58-63
27123900-2	2016	With the goal of enhancing potency and selectivity of the PTP1B inhibitors, a series of methyl salicylate derivatives as ABC type PTP1B inhibitors (P1-P7) were discovered.	methyl salicylate	88-105	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	121-124
27123900-2	2016	With the goal of enhancing potency and selectivity of the PTP1B inhibitors, a series of methyl salicylate derivatives as ABC type PTP1B inhibitors (P1-P7) were discovered.	methyl salicylate	88-105	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	130-135
25527285-0	2015	Neuropeptide receptors NPR-1 and NPR-2 regulate Caenorhabditis elegans avoidance response to the plant stress hormone methyl salicylate.	methyl salicylate	118-135	G_PROTEIN_RECEP_F1_2 domain-containing protein	Caenorhabditis elegans	33-38
25527285-4	2015	Here we found that the nematode Caenorhabditis elegans exhibits a strong avoidance response to MeSa, which requires the activities of two closely related neuropeptide receptors NPR-1 and NPR-2.	methyl salicylate	95-99	G_PROTEIN_RECEP_F1_2 domain-containing protein	Caenorhabditis elegans	177-182
25527285-4	2015	Here we found that the nematode Caenorhabditis elegans exhibits a strong avoidance response to MeSa, which requires the activities of two closely related neuropeptide receptors NPR-1 and NPR-2.	methyl salicylate	95-99	G_PROTEIN_RECEP_F1_2 domain-containing protein	Caenorhabditis elegans	187-192
25527285-5	2015	Molecular analyses suggest that NPR-1 expressed in the RMG inter/motor neurons is required for MeSa avoidance.	methyl salicylate	95-99	G_PROTEIN_RECEP_F1_2 domain-containing protein	Caenorhabditis elegans	32-37
25527285-8	2015	Genetic rescue experiments suggest that NPR-2 expressed in the AIZ interneurons is required for MeSa avoidance.	methyl salicylate	96-100	G_PROTEIN_RECEP_F1_2 domain-containing protein	Caenorhabditis elegans	40-45
25527285-10	2015	Our results suggest that NPR-2 has an important role in regulating animal behavior and that NPR-1 and NPR-2 act on distinct interneurons to affect C. elegans avoidance response to MeSa.	methyl salicylate	180-184	G_PROTEIN_RECEP_F1_2 domain-containing protein	Caenorhabditis elegans	92-97
25527285-10	2015	Our results suggest that NPR-2 has an important role in regulating animal behavior and that NPR-1 and NPR-2 act on distinct interneurons to affect C. elegans avoidance response to MeSa.	methyl salicylate	180-184	G_PROTEIN_RECEP_F1_2 domain-containing protein	Caenorhabditis elegans	102-107