PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
33780118-11	2021	MiR-181a-5p promoted the production of IFN-gamma and cytotoxicity in stimulated NK cells from both mice and human.	mir-181a-5p	0-11	interferon gamma	Mus musculus	39-48
34978772-0	2021	MIR-181A-5P Attenuates Ovalbumin-Induced Allergic Inflammation in Nasal Epithelial Cells by Targeting IL-33/P38 MAPK Pathway.	mir-181a-5p	0-11	interleukin 33	Homo sapiens	102-107
34978772-5	2021	The anti-inflammatory effects of miR-181a-5p were evaluated by examining pro-inflammatory cytokines (interleukin (IL)-1beta, IL-6, tumor necrosis factor-alpha (TNF-alpha)) in the culture of RPMI-2650 cells stimulated by ovalbumin, using quantitative real-time reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay.	mir-181a-5p	33-44	interleukin 1 beta	Homo sapiens	100-123
34978772-5	2021	The anti-inflammatory effects of miR-181a-5p were evaluated by examining pro-inflammatory cytokines (interleukin (IL)-1beta, IL-6, tumor necrosis factor-alpha (TNF-alpha)) in the culture of RPMI-2650 cells stimulated by ovalbumin, using quantitative real-time reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay.	mir-181a-5p	33-44	interleukin 6	Homo sapiens	125-129
34978772-5	2021	The anti-inflammatory effects of miR-181a-5p were evaluated by examining pro-inflammatory cytokines (interleukin (IL)-1beta, IL-6, tumor necrosis factor-alpha (TNF-alpha)) in the culture of RPMI-2650 cells stimulated by ovalbumin, using quantitative real-time reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay.	mir-181a-5p	33-44	tumor necrosis factor	Homo sapiens	131-158
34978772-5	2021	The anti-inflammatory effects of miR-181a-5p were evaluated by examining pro-inflammatory cytokines (interleukin (IL)-1beta, IL-6, tumor necrosis factor-alpha (TNF-alpha)) in the culture of RPMI-2650 cells stimulated by ovalbumin, using quantitative real-time reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay.	mir-181a-5p	33-44	tumor necrosis factor	Homo sapiens	160-169
34220972-0	2021	Downregulation of miR-181a-5p alleviates oxidative stress and inflammation in coronary microembolization-induced myocardial damage by directly targeting XIAP.	mir-181a-5p	18-29	X-linked inhibitor of apoptosis	Rattus norvegicus	153-157
34477472-10	2021	Moreover, miR-181a-5p mimic and SHP2 knockdown significantly reversed the MEG8 overexpression-mediated suppression of JAK2/STAT3 signalling, and promotion of M1 polarization.	mir-181a-5p	10-21	Janus kinase 2	Rattus norvegicus	118-122
34477472-10	2021	Moreover, miR-181a-5p mimic and SHP2 knockdown significantly reversed the MEG8 overexpression-mediated suppression of JAK2/STAT3 signalling, and promotion of M1 polarization.	mir-181a-5p	10-21	signal transducer and activator of transcription 3	Rattus norvegicus	123-128
33904366-8	2021	Finally, Sirt1 overexpression significantly inhibited the impact of miR-181a-5p mimic on apoptosis and inhibited differentiation, while silencing Sirt1 eliminated the inhibitory effects of miR-181a-5p on apoptosis and promoted differentiation via PI3K/AKT pathway.	mir-181a-5p	68-79	sirtuin 1	Homo sapiens	9-14
33904366-8	2021	Finally, Sirt1 overexpression significantly inhibited the impact of miR-181a-5p mimic on apoptosis and inhibited differentiation, while silencing Sirt1 eliminated the inhibitory effects of miR-181a-5p on apoptosis and promoted differentiation via PI3K/AKT pathway.	mir-181a-5p	68-79	AKT serine/threonine kinase 1	Homo sapiens	252-255
33904366-8	2021	Finally, Sirt1 overexpression significantly inhibited the impact of miR-181a-5p mimic on apoptosis and inhibited differentiation, while silencing Sirt1 eliminated the inhibitory effects of miR-181a-5p on apoptosis and promoted differentiation via PI3K/AKT pathway.	mir-181a-5p	189-200	sirtuin 1	Homo sapiens	9-14
33904366-8	2021	Finally, Sirt1 overexpression significantly inhibited the impact of miR-181a-5p mimic on apoptosis and inhibited differentiation, while silencing Sirt1 eliminated the inhibitory effects of miR-181a-5p on apoptosis and promoted differentiation via PI3K/AKT pathway.	mir-181a-5p	189-200	sirtuin 1	Homo sapiens	146-151
33904366-8	2021	Finally, Sirt1 overexpression significantly inhibited the impact of miR-181a-5p mimic on apoptosis and inhibited differentiation, while silencing Sirt1 eliminated the inhibitory effects of miR-181a-5p on apoptosis and promoted differentiation via PI3K/AKT pathway.	mir-181a-5p	189-200	AKT serine/threonine kinase 1	Homo sapiens	252-255
34651657-7	2021	Moreover, the TGF-beta1-induced increase in viability, proliferation, migration, adhesion and collagen production, and the LPS-induced inflammation of LX2 cells were all reversed after MALAT1 knockdown or transfection with miR-181a-5p mimic.	mir-181a-5p	223-234	transforming growth factor beta 1	Homo sapiens	14-23
34942624-15	2022	Activating HMGB1/RAGE reversed the protective effect of miR-181a-5p overexpression on AR and induced the development of asthma.	mir-181a-5p	56-67	high mobility group box 1	Mus musculus	11-16
34942624-15	2022	Activating HMGB1/RAGE reversed the protective effect of miR-181a-5p overexpression on AR and induced the development of asthma.	mir-181a-5p	56-67	advanced glycosylation end product-specific receptor	Mus musculus	17-21
34220972-18	2021	Finally, in vitro rescue experiments revealed that knockdown of XIAP could abolish the protective effects of miR-181a-5p knockdown on hypoxia-induced cardiomyocyte oxidative stress and inflammatory injury.	mir-181a-5p	109-120	X-linked inhibitor of apoptosis	Rattus norvegicus	64-68
34220972-19	2021	CONCLUSIONS: Downregulation of miR-181a-5p alleviates CME-induced myocardial damage by suppressing myocardial oxidative stress and inflammation through directly targeting XIAP.	mir-181a-5p	31-42	X-linked inhibitor of apoptosis	Rattus norvegicus	171-175
35339759-10	2022	miR-181a-5p inhibited NRAS expression at both the mRNA and protein levels.	mir-181a-5p	0-11	NRAS proto-oncogene, GTPase	Homo sapiens	22-26
35468097-9	2022	MiR-181a-5p mimics inhibited the activity of p-ERK1/2, MMP2 and MMP9 in vivo, as shown by Western blotting and immunohistochemistry labeling.	mir-181a-5p	0-11	mitogen-activated protein kinase 3	Homo sapiens	47-53
35468097-9	2022	MiR-181a-5p mimics inhibited the activity of p-ERK1/2, MMP2 and MMP9 in vivo, as shown by Western blotting and immunohistochemistry labeling.	mir-181a-5p	0-11	matrix metallopeptidase 2	Homo sapiens	55-59
35468097-9	2022	MiR-181a-5p mimics inhibited the activity of p-ERK1/2, MMP2 and MMP9 in vivo, as shown by Western blotting and immunohistochemistry labeling.	mir-181a-5p	0-11	matrix metallopeptidase 9	Homo sapiens	64-68
35468097-11	2022	Additionally, miR-181a-5p mimics lowered p-ERK1/2, MMP2 and MMP9 levels in ECA109 cells, which were restored by MEK1-OE lentivirus.	mir-181a-5p	14-25	mitogen-activated protein kinase 3	Homo sapiens	43-49
35468097-11	2022	Additionally, miR-181a-5p mimics lowered p-ERK1/2, MMP2 and MMP9 levels in ECA109 cells, which were restored by MEK1-OE lentivirus.	mir-181a-5p	14-25	matrix metallopeptidase 2	Homo sapiens	51-55
35468097-11	2022	Additionally, miR-181a-5p mimics lowered p-ERK1/2, MMP2 and MMP9 levels in ECA109 cells, which were restored by MEK1-OE lentivirus.	mir-181a-5p	14-25	matrix metallopeptidase 9	Homo sapiens	60-64
35468097-11	2022	Additionally, miR-181a-5p mimics lowered p-ERK1/2, MMP2 and MMP9 levels in ECA109 cells, which were restored by MEK1-OE lentivirus.	mir-181a-5p	14-25	mitogen-activated protein kinase kinase 1	Homo sapiens	112-116
35468097-12	2022	MEK1-OE Lentivirus significantly reversed the function induced by miR-181a-5p mimics in ECA109 cells.	mir-181a-5p	66-77	mitogen-activated protein kinase kinase 1	Homo sapiens	0-4
35468097-14	2022	In short, repressed ERK-MMP pathway mediated by miR-181a-5p can inhibit cell migration, invasion and proliferation by targeting MAP2K1 (MEK1) in ESCC.	mir-181a-5p	48-59	mitogen-activated protein kinase 1	Homo sapiens	20-23
35468097-14	2022	In short, repressed ERK-MMP pathway mediated by miR-181a-5p can inhibit cell migration, invasion and proliferation by targeting MAP2K1 (MEK1) in ESCC.	mir-181a-5p	48-59	matrix metallopeptidase 2	Homo sapiens	24-27
35468097-14	2022	In short, repressed ERK-MMP pathway mediated by miR-181a-5p can inhibit cell migration, invasion and proliferation by targeting MAP2K1 (MEK1) in ESCC.	mir-181a-5p	48-59	mitogen-activated protein kinase kinase 1	Homo sapiens	128-134
35468097-14	2022	In short, repressed ERK-MMP pathway mediated by miR-181a-5p can inhibit cell migration, invasion and proliferation by targeting MAP2K1 (MEK1) in ESCC.	mir-181a-5p	48-59	mitogen-activated protein kinase kinase 1	Homo sapiens	136-140
35610079-8	2022	MiR-181a-5p is targeted by circSLC8A1, and its mimic reversed the effect of circSLC8A1 on the biological function of HKFs.	mir-181a-5p	0-11	solute carrier family 8 member A1	Homo sapiens	27-37
35610079-8	2022	MiR-181a-5p is targeted by circSLC8A1, and its mimic reversed the effect of circSLC8A1 on the biological function of HKFs.	mir-181a-5p	0-11	solute carrier family 8 member A1	Homo sapiens	76-86
35283358-0	2022	MiR-181a-5p alleviates the inflammatory response of PC12 cells by inhibiting high-mobility group box-1 protein expression.	mir-181a-5p	0-11	high mobility group box 1	Rattus norvegicus	77-102
35283358-14	2022	In conclusion, miR-181a-5p attenuated the inflammatory response of LPS-induced PC12 cells by directly inhibiting HMGB1; thus, miR-181a-5p may serve as a therapeutic target in SCI.	mir-181a-5p	15-26	high mobility group box 1	Rattus norvegicus	113-118
35283358-14	2022	In conclusion, miR-181a-5p attenuated the inflammatory response of LPS-induced PC12 cells by directly inhibiting HMGB1; thus, miR-181a-5p may serve as a therapeutic target in SCI.	mir-181a-5p	126-137	high mobility group box 1	Rattus norvegicus	113-118
35339759-12	2022	CONCLUSION: miR-181a-5p was significantly downregulated during the development of RB, and it suppressed the malignant behaviors of RB cells by targeting NRAS.	mir-181a-5p	12-23	NRAS proto-oncogene, GTPase	Homo sapiens	153-157
35092121-11	2022	Moreover, miR-181a-5p is the functional molecule in M1 macrophage-derived exosomes and plays a vital role in inhibiting cell proliferation and promoting apoptosis by targeting ETS1 and STK16.	mir-181a-5p	10-21	E26 avian leukemia oncogene 1, 5' domain	Mus musculus	176-180
35310933-8	2022	Overall, miR-181a-5p promotes osteosarcoma progression via PTEN/AKT pathway and it is a promising therapeutic target to treat osteosarcoma.	mir-181a-5p	9-20	phosphatase and tensin homolog	Homo sapiens	59-63
35310933-8	2022	Overall, miR-181a-5p promotes osteosarcoma progression via PTEN/AKT pathway and it is a promising therapeutic target to treat osteosarcoma.	mir-181a-5p	9-20	AKT serine/threonine kinase 1	Homo sapiens	64-67
35092121-11	2022	Moreover, miR-181a-5p is the functional molecule in M1 macrophage-derived exosomes and plays a vital role in inhibiting cell proliferation and promoting apoptosis by targeting ETS1 and STK16.	mir-181a-5p	10-21	serine/threonine kinase 16	Mus musculus	185-190
34999393-8	2022	Mechanistically, PRP had the similar effects as miR-181a-5p antagomir on RSV-induced apoptosis and inflammation in HEp-2 cells via upregulating BCL2, MLL3 and SIRT1, which could be reversed by miR-181a-5p mimic.	mir-181a-5p	48-59	BCL2 apoptosis regulator	Homo sapiens	144-148
34999393-8	2022	Mechanistically, PRP had the similar effects as miR-181a-5p antagomir on RSV-induced apoptosis and inflammation in HEp-2 cells via upregulating BCL2, MLL3 and SIRT1, which could be reversed by miR-181a-5p mimic.	mir-181a-5p	48-59	lysine methyltransferase 2C	Homo sapiens	150-154
34999393-8	2022	Mechanistically, PRP had the similar effects as miR-181a-5p antagomir on RSV-induced apoptosis and inflammation in HEp-2 cells via upregulating BCL2, MLL3 and SIRT1, which could be reversed by miR-181a-5p mimic.	mir-181a-5p	48-59	sirtuin 1	Homo sapiens	159-164
34999393-8	2022	Mechanistically, PRP had the similar effects as miR-181a-5p antagomir on RSV-induced apoptosis and inflammation in HEp-2 cells via upregulating BCL2, MLL3 and SIRT1, which could be reversed by miR-181a-5p mimic.	mir-181a-5p	193-204	complement component 4 binding protein alpha	Homo sapiens	17-20
35073549-0	2022	Role and mechanism of miR-181a-5p in mice with chronic obstructive pulmonary disease by regulating HMGB1 and the NF-kappaB pathway.	mir-181a-5p	22-33	high mobility group box 1	Mus musculus	99-104
35073549-0	2022	Role and mechanism of miR-181a-5p in mice with chronic obstructive pulmonary disease by regulating HMGB1 and the NF-kappaB pathway.	mir-181a-5p	22-33	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	113-122
35073549-16	2022	Briefly, miR-181a-5p targets HMGB1 to inhibit the NF-kappaB pathway, thus alleviating the inflammatory response in COPD mice.	mir-181a-5p	9-20	high mobility group box 1	Mus musculus	29-34
35073549-16	2022	Briefly, miR-181a-5p targets HMGB1 to inhibit the NF-kappaB pathway, thus alleviating the inflammatory response in COPD mice.	mir-181a-5p	9-20	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	50-59
33001231-15	2021	miR-181a-5p was in part responsible for the downregulation of occludin in placentas from d-GDM pregnancies.	mir-181a-5p	0-11	occludin	Homo sapiens	62-70
34951340-0	2022	MiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN/AKT pathway.	mir-181a-5p	0-11	NDRG family member 2	Homo sapiens	89-94
34951340-0	2022	MiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN/AKT pathway.	mir-181a-5p	0-11	phosphatase and tensin homolog	Homo sapiens	118-122
34951340-0	2022	MiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN/AKT pathway.	mir-181a-5p	0-11	AKT serine/threonine kinase 1	Homo sapiens	123-126
34951340-11	2022	Rescue experiments showed that restoring NDRG2 abolished the effects caused by miR-181a-5p in breast cancer cells.	mir-181a-5p	79-90	NDRG family member 2	Homo sapiens	41-46
34951340-12	2022	In conclusion, miR-181a-5p facilitated tumor progression through NDRG2-induced activation of PTEN/AKT signaling pathway of breast cancer, suggesting that focusing on miR-181a-5p may provide new insight for breast cancer therapy.Abbreviations Brdu: Bromodeoxyuridine; CCK-8: Cell Counting Kit-8; miRNA: microRNAs; mut: mutant; RT-qPCR: real-time quantitative polymerase chain reaction; UTR: untranslated region; WT: wild-type.	mir-181a-5p	15-26	NDRG family member 2	Homo sapiens	65-70
34951340-12	2022	In conclusion, miR-181a-5p facilitated tumor progression through NDRG2-induced activation of PTEN/AKT signaling pathway of breast cancer, suggesting that focusing on miR-181a-5p may provide new insight for breast cancer therapy.Abbreviations Brdu: Bromodeoxyuridine; CCK-8: Cell Counting Kit-8; miRNA: microRNAs; mut: mutant; RT-qPCR: real-time quantitative polymerase chain reaction; UTR: untranslated region; WT: wild-type.	mir-181a-5p	15-26	phosphatase and tensin homolog	Homo sapiens	93-97
34951340-12	2022	In conclusion, miR-181a-5p facilitated tumor progression through NDRG2-induced activation of PTEN/AKT signaling pathway of breast cancer, suggesting that focusing on miR-181a-5p may provide new insight for breast cancer therapy.Abbreviations Brdu: Bromodeoxyuridine; CCK-8: Cell Counting Kit-8; miRNA: microRNAs; mut: mutant; RT-qPCR: real-time quantitative polymerase chain reaction; UTR: untranslated region; WT: wild-type.	mir-181a-5p	15-26	AKT serine/threonine kinase 1	Homo sapiens	98-101
34951340-12	2022	In conclusion, miR-181a-5p facilitated tumor progression through NDRG2-induced activation of PTEN/AKT signaling pathway of breast cancer, suggesting that focusing on miR-181a-5p may provide new insight for breast cancer therapy.Abbreviations Brdu: Bromodeoxyuridine; CCK-8: Cell Counting Kit-8; miRNA: microRNAs; mut: mutant; RT-qPCR: real-time quantitative polymerase chain reaction; UTR: untranslated region; WT: wild-type.	mir-181a-5p	166-177	NDRG family member 2	Homo sapiens	65-70
34951340-12	2022	In conclusion, miR-181a-5p facilitated tumor progression through NDRG2-induced activation of PTEN/AKT signaling pathway of breast cancer, suggesting that focusing on miR-181a-5p may provide new insight for breast cancer therapy.Abbreviations Brdu: Bromodeoxyuridine; CCK-8: Cell Counting Kit-8; miRNA: microRNAs; mut: mutant; RT-qPCR: real-time quantitative polymerase chain reaction; UTR: untranslated region; WT: wild-type.	mir-181a-5p	166-177	phosphatase and tensin homolog	Homo sapiens	93-97
34951340-12	2022	In conclusion, miR-181a-5p facilitated tumor progression through NDRG2-induced activation of PTEN/AKT signaling pathway of breast cancer, suggesting that focusing on miR-181a-5p may provide new insight for breast cancer therapy.Abbreviations Brdu: Bromodeoxyuridine; CCK-8: Cell Counting Kit-8; miRNA: microRNAs; mut: mutant; RT-qPCR: real-time quantitative polymerase chain reaction; UTR: untranslated region; WT: wild-type.	mir-181a-5p	166-177	AKT serine/threonine kinase 1	Homo sapiens	98-101
33907874-12	2021	Moreover, overexpressed PDCD4 abolished the inhibition on inflammation and apoptosis caused by miR-181a-5p overexpression.	mir-181a-5p	95-106	programmed cell death 4	Homo sapiens	24-29
33360253-13	2021	CONCLUSION: miR-181a-5p suppression activated Wnt/beta-catenin pathway and sequentially attenuated cerebral ischemic injury by targeting En2.	mir-181a-5p	12-23	catenin (cadherin associated protein), beta 1	Mus musculus	50-62
33360253-13	2021	CONCLUSION: miR-181a-5p suppression activated Wnt/beta-catenin pathway and sequentially attenuated cerebral ischemic injury by targeting En2.	mir-181a-5p	12-23	engrailed 2	Mus musculus	137-140
33529508-12	2021	MiR-181a-5p directly bound to ANRIL and was upregulated by irradiation in a dose-dependent manner.	mir-181a-5p	0-11	CDKN2B antisense RNA 1	Homo sapiens	30-35
33529508-15	2021	The overexpression of ANRIL partially reversed COS-induced apoptosis and the inhibition rate; the upregulation of miR-181a-5p could counteract the impact of ANRIL regulation in cells.	mir-181a-5p	114-125	CDKN2B antisense RNA 1	Homo sapiens	22-27
33529508-15	2021	The overexpression of ANRIL partially reversed COS-induced apoptosis and the inhibition rate; the upregulation of miR-181a-5p could counteract the impact of ANRIL regulation in cells.	mir-181a-5p	114-125	CDKN2B antisense RNA 1	Homo sapiens	157-162
32346884-0	2020	Overexpression of miR-181a-5p inhibits retinal neovascularization through endocan and the ERK1/2 signaling pathway.	mir-181a-5p	18-29	endothelial cell specific molecule 1	Homo sapiens	74-81
32346884-0	2020	Overexpression of miR-181a-5p inhibits retinal neovascularization through endocan and the ERK1/2 signaling pathway.	mir-181a-5p	18-29	mitogen-activated protein kinase 3	Mus musculus	90-96
33000228-6	2020	Furthermore, miR-181a-5p was reported as a target of SNHG12 and was negatively regulated by SNHG12.	mir-181a-5p	13-24	small nucleolar RNA host gene 12	Homo sapiens	53-59
33002329-11	2020	Our results suggest that circHivep2 regulates microglia activation in the progression of epilepsy by interfering with miR-181a-5p to promote SOCS2 expression, indicating that circHivep2 may serve as a therapeutic tool to prevent the development of epilepsy.	mir-181a-5p	118-129	suppressor of cytokine signaling 2	Mus musculus	141-146
33251387-17	2020	miR-181a-5p transfection induced expression levels of OGT were diminished compared to those in the control group.	mir-181a-5p	0-11	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	54-57
33000228-6	2020	Furthermore, miR-181a-5p was reported as a target of SNHG12 and was negatively regulated by SNHG12.	mir-181a-5p	13-24	small nucleolar RNA host gene 12	Homo sapiens	92-98
32921988-11	2020	Meanwhile, PVT1 bound to miR-181a-5p in HK-2 cells.	mir-181a-5p	25-36	Pvt1 oncogene	Mus musculus	11-15
32968457-0	2020	miR-181a-5p inhibits the proliferation and invasion of drug-resistant glioblastoma cells by targeting F-box protein 11 expression.	mir-181a-5p	0-11	F-box protein 11	Homo sapiens	102-118
32982425-11	2020	Moreover, miR-181a-5p inhibitor abolished SNHG7 silencing induced inhibition on proliferation, migration and invasion in NSCLC.	mir-181a-5p	10-21	small nucleolar RNA host gene 7	Homo sapiens	42-47
33042355-8	2020	Furthermore, downregulated LATS2 could abolish the alterations in ACC cells induced by miR-181a-5p silencing.	mir-181a-5p	87-98	large tumor suppressor kinase 2	Homo sapiens	27-32
33042355-9	2020	MiR-181a-5p inhibition upregulated LATS2 to suppress malignant behavior of ACC cells in vivo and in vitro.	mir-181a-5p	0-11	large tumor suppressor kinase 2	Homo sapiens	35-40
32461588-0	2020	Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy.	mir-181a-5p	14-25	sirtuin 1	Rattus norvegicus	104-109
32461588-6	2020	Moreover, miR-181a-5p inhibition exerted a seizure-suppressing effect via SIRT1 upregulation.	mir-181a-5p	10-21	sirtuin 1	Rattus norvegicus	74-79
32921988-13	2020	Furthermore, miR-181a-5p antagonist could significantly reverse the anti-fibrotic effect of PVT1 knockdown.	mir-181a-5p	13-24	Pvt1 oncogene	Mus musculus	92-96
32612385-7	2020	The interaction between miR-181a-5p and CBLB was evaluated by luciferase reporter assay and RIP assay.	mir-181a-5p	24-35	Cbl proto-oncogene B	Homo sapiens	40-44
32612385-14	2020	Conclusion: miR-181a-5p enhanced the sensitivity of cells to cisplatin in EAC by targeting CBLB, indicating a promising sensitizer of cisplatin therapy in clinical esophageal cancer.	mir-181a-5p	12-23	Cbl proto-oncogene B	Homo sapiens	91-95
30666158-13	2019	Mechanistic investigations showed that SNHG6 acted as a competing endogenous RNA for miR-181a-5p and attenuated the inhibitory effect of miR-181a-5p on E2F5.	mir-181a-5p	85-96	small nucleolar RNA host gene 6	Homo sapiens	39-44
30666158-13	2019	Mechanistic investigations showed that SNHG6 acted as a competing endogenous RNA for miR-181a-5p and attenuated the inhibitory effect of miR-181a-5p on E2F5.	mir-181a-5p	137-148	small nucleolar RNA host gene 6	Homo sapiens	39-44
30666158-13	2019	Mechanistic investigations showed that SNHG6 acted as a competing endogenous RNA for miR-181a-5p and attenuated the inhibitory effect of miR-181a-5p on E2F5.	mir-181a-5p	137-148	E2F transcription factor 5	Homo sapiens	152-156
29339719-7	2018	Thus, we demonstrated here that miR-181a-5p suppresses the invasion and migration of cytotrophoblasts, and its inhibitory effects were at least partially mediated by the suppression of IGF2BP2 expression, thus shedding new light on the roles of miR-181a-5p in the pathogenesis of severe pre-eclampsia.	mir-181a-5p	32-43	insulin like growth factor 2 mRNA binding protein 2	Homo sapiens	185-192
29339719-7	2018	Thus, we demonstrated here that miR-181a-5p suppresses the invasion and migration of cytotrophoblasts, and its inhibitory effects were at least partially mediated by the suppression of IGF2BP2 expression, thus shedding new light on the roles of miR-181a-5p in the pathogenesis of severe pre-eclampsia.	mir-181a-5p	245-256	insulin like growth factor 2 mRNA binding protein 2	Homo sapiens	185-192
32765511-12	2020	Nicotine exposure of CD8+ cells induced the expression of miR-150-5p and miR-181a-5p in the naive-memory cells in vitro.	mir-181a-5p	73-84	CD8a molecule	Homo sapiens	21-24
32290769-0	2020	MiR-181a-5p is involved in the cardiomyocytes apoptosis induced by hypoxia-reoxygenation through regulating SIRT1.	mir-181a-5p	0-11	sirtuin 1	Homo sapiens	108-113
32290769-6	2020	On the other hand, miR-181a-5p inhibited apoptosis and elevated Bcl-2 expression while decreasing the expressions of Bax and Caspase 3 in treated cells, but the effects of miR-181a-5p could be rescued by SIRT1.	mir-181a-5p	19-30	BCL2 apoptosis regulator	Homo sapiens	64-69
32290769-6	2020	On the other hand, miR-181a-5p inhibited apoptosis and elevated Bcl-2 expression while decreasing the expressions of Bax and Caspase 3 in treated cells, but the effects of miR-181a-5p could be rescued by SIRT1.	mir-181a-5p	19-30	BCL2 associated X, apoptosis regulator	Homo sapiens	117-120
32290769-6	2020	On the other hand, miR-181a-5p inhibited apoptosis and elevated Bcl-2 expression while decreasing the expressions of Bax and Caspase 3 in treated cells, but the effects of miR-181a-5p could be rescued by SIRT1.	mir-181a-5p	19-30	caspase 3	Homo sapiens	125-134
32290769-6	2020	On the other hand, miR-181a-5p inhibited apoptosis and elevated Bcl-2 expression while decreasing the expressions of Bax and Caspase 3 in treated cells, but the effects of miR-181a-5p could be rescued by SIRT1.	mir-181a-5p	19-30	sirtuin 1	Homo sapiens	204-209
32290769-6	2020	On the other hand, miR-181a-5p inhibited apoptosis and elevated Bcl-2 expression while decreasing the expressions of Bax and Caspase 3 in treated cells, but the effects of miR-181a-5p could be rescued by SIRT1.	mir-181a-5p	172-183	sirtuin 1	Homo sapiens	204-209
32290769-7	2020	In conclusion, miR-181a-5p involved in H/R-induced cardiomyocytes apoptosis through regulating SIRT1, which might become a novel direction for related diseases.	mir-181a-5p	15-26	sirtuin 1	Homo sapiens	95-100
32440218-17	2020	Moreover, miR-181a-5p inhibition or E2F7 overexpression abolished the effect of SNHG7 knockdown on the progression of NSCLC cells.	mir-181a-5p	10-21	small nucleolar RNA host gene 7	Mus musculus	80-85