PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
33859065-4	2021	The conventional whole-cell patch clamp results showed that fargesin, magnolin, and eudesmin significantly inhibited SOCE and thus human primary CD4+ T lymphocyte proliferation, as well as allergen-induced histamine release in mast cells.	eudesmin	84-92	CD4 molecule	Homo sapiens	145-148
29171326-10	2017	By treating with EDN (10, 20 and 40 muM), expression of caspase-3, caspase-9, Bax, P53 and phosphorylated JNK in A549 cells were significantly upregulated, whereas expression of Bcl-2 and Akt phosphorylation were significantly down-regulated.	eudesmin	17-20	caspase 3	Mus musculus	56-65
29171326-10	2017	By treating with EDN (10, 20 and 40 muM), expression of caspase-3, caspase-9, Bax, P53 and phosphorylated JNK in A549 cells were significantly upregulated, whereas expression of Bcl-2 and Akt phosphorylation were significantly down-regulated.	eudesmin	17-20	caspase 9	Mus musculus	67-76
29171326-10	2017	By treating with EDN (10, 20 and 40 muM), expression of caspase-3, caspase-9, Bax, P53 and phosphorylated JNK in A549 cells were significantly upregulated, whereas expression of Bcl-2 and Akt phosphorylation were significantly down-regulated.	eudesmin	17-20	BCL2-associated X protein	Mus musculus	78-81
29171326-10	2017	By treating with EDN (10, 20 and 40 muM), expression of caspase-3, caspase-9, Bax, P53 and phosphorylated JNK in A549 cells were significantly upregulated, whereas expression of Bcl-2 and Akt phosphorylation were significantly down-regulated.	eudesmin	17-20	transformation related protein 53, pseudogene	Mus musculus	83-86
29171326-10	2017	By treating with EDN (10, 20 and 40 muM), expression of caspase-3, caspase-9, Bax, P53 and phosphorylated JNK in A549 cells were significantly upregulated, whereas expression of Bcl-2 and Akt phosphorylation were significantly down-regulated.	eudesmin	17-20	mitogen-activated protein kinase 8	Mus musculus	106-109
29171326-10	2017	By treating with EDN (10, 20 and 40 muM), expression of caspase-3, caspase-9, Bax, P53 and phosphorylated JNK in A549 cells were significantly upregulated, whereas expression of Bcl-2 and Akt phosphorylation were significantly down-regulated.	eudesmin	17-20	B cell leukemia/lymphoma 2	Mus musculus	178-183
29171326-10	2017	By treating with EDN (10, 20 and 40 muM), expression of caspase-3, caspase-9, Bax, P53 and phosphorylated JNK in A549 cells were significantly upregulated, whereas expression of Bcl-2 and Akt phosphorylation were significantly down-regulated.	eudesmin	17-20	thymoma viral proto-oncogene 1	Mus musculus	188-191
29171326-11	2017	Interestingly, EDN-induced apoptosis could be attenuated by JNK inhibitor.	eudesmin	15-18	mitogen-activated protein kinase 8	Mus musculus	60-63
19277963-2	2009	The compounds including schizandrins, schisandrols, gomisins, fargesin, eudesmin and lirioresinol B dimethyl ether, inhibited 5-LOX-catalysed leukotriene production from A23187-treated rat basophilic leukemia (RBL-1) cells at concentrations of 1-100 microm.	eudesmin	72-80	arachidonate 5-lipoxygenase	Rattus norvegicus	126-131
19277963-2	2009	The compounds including schizandrins, schisandrols, gomisins, fargesin, eudesmin and lirioresinol B dimethyl ether, inhibited 5-LOX-catalysed leukotriene production from A23187-treated rat basophilic leukemia (RBL-1) cells at concentrations of 1-100 microm.	eudesmin	72-80	RB transcriptional corepressor like 1	Rattus norvegicus	210-215