PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2515604-3	1989	t-PA with a low content of mannose (man-t-PA) was obtained by treatment with alpha-mannosidase, which cleaves terminal mannose from the carbohydrate side chains of the molecule.	Mannose	27-34	plasminogen activator, tissue type	Homo sapiens	0-4
2515604-3	1989	t-PA with a low content of mannose (man-t-PA) was obtained by treatment with alpha-mannosidase, which cleaves terminal mannose from the carbohydrate side chains of the molecule.	Mannose	27-34	plasminogen activator, tissue type	Homo sapiens	40-44
2515604-3	1989	t-PA with a low content of mannose (man-t-PA) was obtained by treatment with alpha-mannosidase, which cleaves terminal mannose from the carbohydrate side chains of the molecule.	Mannose	119-126	plasminogen activator, tissue type	Homo sapiens	0-4
2515604-3	1989	t-PA with a low content of mannose (man-t-PA) was obtained by treatment with alpha-mannosidase, which cleaves terminal mannose from the carbohydrate side chains of the molecule.	Mannose	119-126	plasminogen activator, tissue type	Homo sapiens	40-44
2515604-4	1989	About 50% of the total mannose was removed from the native t-PA.	Mannose	23-30	plasminogen activator, tissue type	Homo sapiens	59-63
2575378-0	1989	Involvement of protein kinase C in activation of human granulocytes and peritoneal macrophages by type 1 fimbriated (mannose specific) Escherichia coli.	Mannose	117-124	proline rich transmembrane protein 2	Homo sapiens	15-31
2575378-6	1989	In the present study, we used three inhibitors of PKC to examine the possible involvement of the enzyme in activation of human granulocytes and peritoneal macrophages by type 1 fimbriated (mannose-specific) Escherichia coli in the absence of opsonins.	Mannose	189-196	proline rich transmembrane protein 2	Homo sapiens	50-53
2516782-7	1989	The sugar chain of intracellular t-PA was analyzed with endoglycosidase H and N-glycanase, which reduced the molecular weight of t-PA by 4.5-10 kDa, indicating the intracellular presence of a high-mannose type sugar chain and a complex-type sugar chain of t-PA.	Mannose	197-204	plasminogen activator, tissue type	Homo sapiens	33-37
2561054-3	1989	Evidence is presented that the high-mannose-type oligosaccharides with seven, eight and nine mannose residues from both forms of gp120 are recognized by the serum lectin, and that these reactivities are unrelated to CD4 recognition.	Mannose	36-43	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	129-134
2516782-7	1989	The sugar chain of intracellular t-PA was analyzed with endoglycosidase H and N-glycanase, which reduced the molecular weight of t-PA by 4.5-10 kDa, indicating the intracellular presence of a high-mannose type sugar chain and a complex-type sugar chain of t-PA.	Mannose	197-204	plasminogen activator, tissue type	Homo sapiens	129-133
2516782-7	1989	The sugar chain of intracellular t-PA was analyzed with endoglycosidase H and N-glycanase, which reduced the molecular weight of t-PA by 4.5-10 kDa, indicating the intracellular presence of a high-mannose type sugar chain and a complex-type sugar chain of t-PA.	Mannose	197-204	plasminogen activator, tissue type	Homo sapiens	129-133
2516782-8	1989	t-PA secreted from the monensin-treated cells possesses a high-mannose type sugar chain only.	Mannose	63-70	plasminogen activator, tissue type	Homo sapiens	0-4
2583526-7	1989	The difference could be due to decreased glycosylation of the vaccine strain E2 protein, as revealed by [3H]mannose incorporation studies.	Mannose	108-115	ubiquitin conjugating enzyme E2 B	Homo sapiens	77-87
2690078-4	1989	The addition of mannose is completely abolished in the early secretory mutant sec53, attenuated in the late-endoplasmic reticulum-blocked sec18, and unaffected in sec7, which is blocked late in the Golgi phase of secretion.	Mannose	16-23	phosphomannomutase SEC53	Saccharomyces cerevisiae S288C	78-83
2690078-4	1989	The addition of mannose is completely abolished in the early secretory mutant sec53, attenuated in the late-endoplasmic reticulum-blocked sec18, and unaffected in sec7, which is blocked late in the Golgi phase of secretion.	Mannose	16-23	AAA family ATPase SEC18	Saccharomyces cerevisiae S288C	138-143
2554567-4	1989	The release of this component was effectively blocked by 10 mM 1-deoxynojirimycin, an inhibitor of oligosaccharide processing, demonstrating a requirement for processing of high mannose precursor oligosaccharides in the secretion of gp65.	Mannose	178-185	neuroplastin	Homo sapiens	233-237
2627938-0	1989	The interaction of a lung surfactant protein (SP-A) with macrophages is mannose dependent.	Mannose	72-79	surfactant protein A1	Homo sapiens	46-50
2627938-6	1989	Two mannose-dependent recognition mechanisms might mediate SP-A uptake by macrophages.	Mannose	4-11	surfactant protein A1	Homo sapiens	59-63
2627938-8	1989	Second, as SP-A is a mannose-specific lectin itself it could bind to mannose residues on the macrophage"s cell surface.	Mannose	21-28	surfactant protein A1	Homo sapiens	11-15
2627938-8	1989	Second, as SP-A is a mannose-specific lectin itself it could bind to mannose residues on the macrophage"s cell surface.	Mannose	69-76	surfactant protein A1	Homo sapiens	11-15
2816909-0	1989	Time-dependent cleavage of a high-mannose form of Ii to p25 in an intracellular compartment.	Mannose	34-41	tubulin polymerization promoting protein	Homo sapiens	56-59
2816909-1	1989	The cleavage of a high-mannose form of Ii to p25 was demonstrated in an intracellular compartment of B cells.	Mannose	23-30	tubulin polymerization promoting protein	Homo sapiens	45-48
2816909-5	1989	p25 molecules were reduced to about 10,500 daltons by treatment with endoglycosidases F or H. We conclude that p25 was generated from a high mannose form of Ii in the endoplasmic reticulum or cis-Golgi.	Mannose	141-148	tubulin polymerization promoting protein	Homo sapiens	0-3
2816909-5	1989	p25 molecules were reduced to about 10,500 daltons by treatment with endoglycosidases F or H. We conclude that p25 was generated from a high mannose form of Ii in the endoplasmic reticulum or cis-Golgi.	Mannose	141-148	tubulin polymerization promoting protein	Homo sapiens	111-114
2757392-7	1989	Apolipoprotein B-100 was calculated to contain 5-6 mol of high-mannose type and 8-10 mol of complex type oligosaccharides per mole protein.	Mannose	63-70	apolipoprotein B	Homo sapiens	0-20
2684655-3	1989	Terminal alpha 1-3-linked outer chain mannose residues failed to be added to N-linked glycoproteins in sec7 cells at the restrictive temperature.	Mannose	38-45	homeodomain mating type protein alpha2	Saccharomyces cerevisiae S288C	9-18
2574581-3	1989	The carbohydrate of gp120 recognized by lectins was thus arranged in at least four types of glycans: a high mannose type glycan, a bisected hybrid or complex type glycan, a biantennary fucosylated complex type glycan and a triantennary bisected complex type glycan.	Mannose	108-115	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	20-25
2561625-7	1989	The generation of superoxide in the IFN-gamma treated nonadherent monocytes stimulated by E. coli 0-128 was significantly reduced by addition of mannose.	Mannose	145-152	interferon gamma	Homo sapiens	36-45
2679798-4	1989	One of these molecules is the promastigote surface protease, or gp63, which is also a dominant surface antigen; this enzyme is thought to be involved in binding to the macrophage via the cell receptors for mannose and fucose and for the third component of complement.	Mannose	206-213	leishmanolysin like peptidase	Homo sapiens	64-68
2787353-3	1989	rIL-2 also binds OVA, a glycoprotein which contains approximately 50% high mannose chains at a single glycosylation site, and to yeast mannan.	Mannose	75-82	interleukin 2	Rattus norvegicus	0-5
2787357-3	1989	We show that it consists of an IL-1 alpha precursor bound to the plasma membrane via a lectin-like interaction that is specifically dissociated with D-mannose.	Mannose	149-158	interleukin 1 alpha	Mus musculus	31-41
2787357-5	1989	Treatment of macrophages with D-mannose before fixation depleted detectable IL-1 biological activity associated with the membrane.	Mannose	30-39	interleukin 1 complex	Mus musculus	76-80
2787353-5	1989	The conclusion that rIL-2 is a lectin is further supported by the observation that the sequence of IL-2 shares 27% homology with a 33-residue sequence of the carbohydrate-binding domain of human mannose-binding protein.	Mannose	195-202	interleukin 2	Rattus norvegicus	20-25
2787353-5	1989	The conclusion that rIL-2 is a lectin is further supported by the observation that the sequence of IL-2 shares 27% homology with a 33-residue sequence of the carbohydrate-binding domain of human mannose-binding protein.	Mannose	195-202	interleukin 2	Homo sapiens	21-25
2787353-6	1989	The potential physiologic relevance of the carbohydrate binding activity is further elucidated by studies which show that 1) binding of soluble rIL-2 to immobilized uromodulin is enhanced at a pH of 4 to5 in the presence of divalent cations, and 2) neither uromodulin nor the high mannose glycopeptide Man5GlcNAc2Asn blocks the binding of rIL-2 to the IL-2R.	Mannose	281-288	interleukin 2	Rattus norvegicus	144-149
2500441-6	1989	Only mannose was detected in the sugar analysis, with an estimated content of 4.5% w/w corresponding to 2 mannose residues per molecule of IGF-I.	Mannose	5-12	insulin like growth factor 1	Homo sapiens	139-144
2753912-4	1989	Pulse-chase experiments, endo-beta-N-acetylglucosaminidase H treatment, and analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis have indicated that LPL is synthesized in the endoplasmic reticulum as a glycoprotein of Mr = 55,500 bearing two N-oligosaccharide side chains of the high mannose-type.	Mannose	301-308	lipoprotein lipase	Mus musculus	166-169
2525556-3	1989	The enzyme was shown to transfer GlcNAc in beta 1-4 linkage to the D-mannose residue of GlcNAc beta 1-6 (GlcNAc beta 1-2) Man alpha-R where R is either 1-6Man beta-(CH2)8COOCH3 or methyl.	Mannose	67-76	tubulin beta 3 class III	Homo sapiens	43-51
2525556-3	1989	The enzyme was shown to transfer GlcNAc in beta 1-4 linkage to the D-mannose residue of GlcNAc beta 1-6 (GlcNAc beta 1-2) Man alpha-R where R is either 1-6Man beta-(CH2)8COOCH3 or methyl.	Mannose	67-76	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	43-49
2525556-3	1989	The enzyme was shown to transfer GlcNAc in beta 1-4 linkage to the D-mannose residue of GlcNAc beta 1-6 (GlcNAc beta 1-2) Man alpha-R where R is either 1-6Man beta-(CH2)8COOCH3 or methyl.	Mannose	67-76	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	112-120
2525124-3	1989	UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity in these preparations attaches GlcNAc to the mannose residue-linked alpha 1-6 to the beta-linked core mannose of the following Man9GlcNAc oligosaccharide as shown by the arrow.	Mannose	118-125	mannosidase alpha class 1A member 1	Homo sapiens	200-204
2789334-4	1989	Glycosylation of the EGF precursor was determined by (i) the direct incorporation of [3H]mannose and [3H]glucosamine, (ii) metabolic labeling in the presence or absence of glycosylation inhibitors, (iii) enzymatic cleavage of the precursor by N-glycanase or endoglycosidase II, and (iv) lectin chromatography.	Mannose	89-96	epidermal growth factor	Homo sapiens	21-24
2525124-3	1989	UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity in these preparations attaches GlcNAc to the mannose residue-linked alpha 1-6 to the beta-linked core mannose of the following Man9GlcNAc oligosaccharide as shown by the arrow.	Mannose	175-182	mannosidase alpha class 1A member 1	Homo sapiens	200-204
2721453-6	1989	Analysis of [3H]mannose-labeled oligosaccharides on Concanavalin-A-agarose showed 85% binding for those from TSH alpha, 70% for free alpha, and 50% for those from TSH beta.	Mannose	16-23	glycoprotein hormones, alpha subunit	Mus musculus	109-118
2775533-1	1989	Mannosephosphate isomerase (MPI) showed a higher activity than hexokinase (HKM) in its ability to phosphorylate mannose in the spleen, thymus, brain, liver, striated muscles, kidneys, and testes from BALB/c mice.	Mannose	112-119	mannose phosphate isomerase	Mus musculus	0-26
2775533-1	1989	Mannosephosphate isomerase (MPI) showed a higher activity than hexokinase (HKM) in its ability to phosphorylate mannose in the spleen, thymus, brain, liver, striated muscles, kidneys, and testes from BALB/c mice.	Mannose	112-119	mannose phosphate isomerase	Mus musculus	28-31
2721453-6	1989	Analysis of [3H]mannose-labeled oligosaccharides on Concanavalin-A-agarose showed 85% binding for those from TSH alpha, 70% for free alpha, and 50% for those from TSH beta.	Mannose	16-23	thyroid stimulating hormone, beta subunit	Mus musculus	163-171
2718376-2	1989	In pulse/chase labeling experiments of hamster cells with [35S]methionine, Sindbis glycoproteins PE2 and E1 became endo H resistant in two steps at 12.5 and 20.0 min after a 5-min pulse, suggesting that the glycoproteins required this period of time to be transported to the Golgi compartments containing the enzymes which process the high mannose side chains acquired in the endoplasmic reticulum.	Mannose	340-347	ETS2 repressor factor	Homo sapiens	97-100
2507816-6	1989	Mucin, N-acetylneuraminic acid and N-acetyl-D-galactosamine inhibited the adhesion of P. aeruginosa to injured tracheas, but not N-acetylglucosamine, L-fucose, D-mannose and D-galactose.	Mannose	160-169	solute carrier family 13 member 2	Rattus norvegicus	0-5
2656293-1	1989	A glycosylated form of recombinant human insulin-like growth factor I (IGF-I) expressed in Saccharomyces cerevisiae was shown to contain mannose as the only carbohydrate constituent.	Mannose	137-144	insulin like growth factor 1	Homo sapiens	41-69
2656293-1	1989	A glycosylated form of recombinant human insulin-like growth factor I (IGF-I) expressed in Saccharomyces cerevisiae was shown to contain mannose as the only carbohydrate constituent.	Mannose	137-144	insulin like growth factor 1	Homo sapiens	71-76
2759096-3	1989	At this temperature, aminopeptidase N (EC 3.4.11.2) and sucrase-isomaltase (EC 3.2.1.48-10) both accumulated intracellularly, predominantly in their transient, high mannose-glycosylated form characteristic of the newly synthesized enzymes prior to the molecular processing taking place in the Golgi complex.	Mannose	165-172	alanyl aminopeptidase, membrane	Sus scrofa	21-37
2759096-3	1989	At this temperature, aminopeptidase N (EC 3.4.11.2) and sucrase-isomaltase (EC 3.2.1.48-10) both accumulated intracellularly, predominantly in their transient, high mannose-glycosylated form characteristic of the newly synthesized enzymes prior to the molecular processing taking place in the Golgi complex.	Mannose	165-172	sucrase-isomaltase	Sus scrofa	56-74
2665812-7	1989	In the presence of methylmercuric hydroxide, the CR1 translation product, unlike most translation products, had the same molecular weight in gel electrophoresis as the high-mannose-containing pro-CR1 and was 15-20K larger than nonglycosylated CR1.	Mannose	173-180	complement C3b/C4b receptor 1 (Knops blood group)	Homo sapiens	49-52
2665812-7	1989	In the presence of methylmercuric hydroxide, the CR1 translation product, unlike most translation products, had the same molecular weight in gel electrophoresis as the high-mannose-containing pro-CR1 and was 15-20K larger than nonglycosylated CR1.	Mannose	173-180	complement C3b/C4b receptor 1 (Knops blood group)	Homo sapiens	196-199
2665812-7	1989	In the presence of methylmercuric hydroxide, the CR1 translation product, unlike most translation products, had the same molecular weight in gel electrophoresis as the high-mannose-containing pro-CR1 and was 15-20K larger than nonglycosylated CR1.	Mannose	173-180	complement C3b/C4b receptor 1 (Knops blood group)	Homo sapiens	196-199
2469767-3	1989	In this report we show that native and recombinant human MBP can serve in an opsonic role in serum and thereby enhance clearance of mannose rich pathogens by phagocytes.	Mannose	132-139	myelin basic protein	Homo sapiens	57-60
2469767-4	1989	MBP binds to wild-type virulent Salmonella montevideo that express a mannose-rich O-polysaccharide.	Mannose	69-76	myelin basic protein	Homo sapiens	0-3
2744219-0	1989	Carbohydrate moieties of small placental hCG: requirement of mannose structure for biological activity.	Mannose	61-68	chorionic gonadotropin subunit beta 5	Homo sapiens	41-44
2665372-3	1989	The first type, including all strains containing FLO 1, FLO 4, FLO 5, FLO 8 and TUP 1, were partially inhibited by mannose only.	Mannose	115-122	flocculin FLO1	Saccharomyces cerevisiae S288C	49-54
2665372-3	1989	The first type, including all strains containing FLO 1, FLO 4, FLO 5, FLO 8 and TUP 1, were partially inhibited by mannose only.	Mannose	115-122	flocculin FLO1	Saccharomyces cerevisiae S288C	56-61
2665372-3	1989	The first type, including all strains containing FLO 1, FLO 4, FLO 5, FLO 8 and TUP 1, were partially inhibited by mannose only.	Mannose	115-122	flocculin FLO5	Saccharomyces cerevisiae S288C	63-68
2665372-3	1989	The first type, including all strains containing FLO 1, FLO 4, FLO 5, FLO 8 and TUP 1, were partially inhibited by mannose only.	Mannose	115-122	FLO8	Saccharomyces cerevisiae S288C	70-75
2665372-3	1989	The first type, including all strains containing FLO 1, FLO 4, FLO 5, FLO 8 and TUP 1, were partially inhibited by mannose only.	Mannose	115-122	chromatin-silencing transcriptional regulator TUP1	Saccharomyces cerevisiae S288C	80-85
2665372-9	1989	It is proposed that this indicates two entirely distinct mechanisms of flocculation, probably involving a mannose-specific lectin in the FLO 1 type and a broad specificity lectin in the NewFLO type.	Mannose	106-113	flocculin FLO1	Saccharomyces cerevisiae S288C	137-142
2657387-8	1989	These results were consistent with a role for the Sec59 protein in the transfer of mannose to dolichol-linked oligosaccharide.	Mannose	83-90	dolichol kinase	Saccharomyces cerevisiae S288C	50-55
2712832-0	1989	Kinetics of the glycation of bovine serum albumin by mannose and fucose in vitro.	Mannose	53-60	albumin	Homo sapiens	36-49
2712832-1	1989	Glycation of bovine serum albumin was measured for mannose and fucose at 37 degrees C. Mannose as well as fucose demonstrated an initial rapid increase in rate of formation of total adducts followed by a slower secondary reaction.	Mannose	51-58	albumin	Homo sapiens	20-33
2712832-1	1989	Glycation of bovine serum albumin was measured for mannose and fucose at 37 degrees C. Mannose as well as fucose demonstrated an initial rapid increase in rate of formation of total adducts followed by a slower secondary reaction.	Mannose	87-94	albumin	Homo sapiens	20-33
2503497-1	1989	Interferon-gamma produced by the human myelomonocyte cell line HBL-38 contained galactose, mannose, fucose, N-acetylglucosamine, and N-acetylneuraminic acid as sugar components.	Mannose	91-98	interferon gamma	Homo sapiens	0-16
2925680-3	1989	Class E Thy-1- cells produce truncated high mannose oligosaccharides that lack 4 mannose residues from the alpha 1,6-branch of the core beta-linked mannose residue; three of the missing residues are potential phosphorylation sites.	Mannose	44-51	thymus cell antigen 1, theta	Mus musculus	8-13
2925680-3	1989	Class E Thy-1- cells produce truncated high mannose oligosaccharides that lack 4 mannose residues from the alpha 1,6-branch of the core beta-linked mannose residue; three of the missing residues are potential phosphorylation sites.	Mannose	81-88	thymus cell antigen 1, theta	Mus musculus	8-13
2736558-4	1989	The mannopyranose units have the chair conformations 4C(D) with C-5" and C-2" deviating from the best plane through the other four atoms of the ring by -0.68 and +0.53 A in the nonreducing group, and C-3 and O-5 deviating from the mean plane through the other four atoms by +0.57 and -0.66 A, respectively, in the "potentially" reducing residue.	Mannose	4-17	complement C2	Homo sapiens	73-76
2736558-4	1989	The mannopyranose units have the chair conformations 4C(D) with C-5" and C-2" deviating from the best plane through the other four atoms of the ring by -0.68 and +0.53 A in the nonreducing group, and C-3 and O-5 deviating from the mean plane through the other four atoms by +0.57 and -0.66 A, respectively, in the "potentially" reducing residue.	Mannose	4-17	complement C3	Homo sapiens	200-211
2538547-7	1989	Therefore, probably half of the glycan moieties of gp120/160 are composed of high mannose and biantennary chains, the other half being triantennary species.	Mannose	82-89	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	51-60
2744219-5	1989	Alpha-Mannosidase and endoglycosidase H hydrolyzed mannose and the high mannose-GlcNAc moieties, respectively, from alpha- and beta-subunits of SP-hCG, but not from the subunits of authentic hCG.	Mannose	51-58	chorionic gonadotropin subunit beta 5	Homo sapiens	147-150
2744219-5	1989	Alpha-Mannosidase and endoglycosidase H hydrolyzed mannose and the high mannose-GlcNAc moieties, respectively, from alpha- and beta-subunits of SP-hCG, but not from the subunits of authentic hCG.	Mannose	72-79	chorionic gonadotropin subunit beta 5	Homo sapiens	147-150
2643568-4	1989	Four genes, draA, draC, draD, and draE, were required for full mannose-resistant hemagglutination expression.	Mannose	63-70	EGF containing fibulin extracellular matrix protein 1	Homo sapiens	24-28
2518593-10	1989	In the canine model of NCL lipid bound mannose clearly predominated, the GP component being in low amount on average.	Mannose	39-46	nucleolin	Canis lupus familiaris	23-26
2563273-0	1989	Mitogenic stimulation of human B lymphocytes by the mannose-specific adhesin on Escherichia coli type 1 fimbriae.	Mannose	52-59	adhesin	Escherichia coli	69-76
2563273-1	1989	Escherichia coli type 1 fimbriae contain in association with the major structural protein a lectin-like adhesin moiety that mediates attachment of E. coli to mannose-containing receptors on the surface of host cells.	Mannose	158-165	adhesin	Escherichia coli	104-111
2563273-2	1989	We have investigated the lymphocyte mitogenic activity of this mannose-specific adhesin by comparing the ability of purified wild type type 1 fimbriae containing the adhesin and mutant type 1 fimbriae lacking the adhesin to stimulate proliferation in human lymphocytes.	Mannose	63-70	adhesin	Escherichia coli	80-87
2563273-2	1989	We have investigated the lymphocyte mitogenic activity of this mannose-specific adhesin by comparing the ability of purified wild type type 1 fimbriae containing the adhesin and mutant type 1 fimbriae lacking the adhesin to stimulate proliferation in human lymphocytes.	Mannose	63-70	adhesin	Escherichia coli	166-173
2463989-9	1989	Removal of high mannose oligosaccarides by endo-beta-N-acetylglucosaminidase H treatment reduced the apparent Mr of the precursor but not the mature protein.	Mannose	16-23	O-GlcNAcase	Homo sapiens	48-76
2482280-11	1989	In the dog model of NCL lipid bound mannose clearly predominated, the GP component being concentrated in the cytoplasm and on the periphery od some storage granules.	Mannose	36-43	nucleolin	Canis lupus familiaris	20-23
2562506-3	1989	The results obtained indicate that ovalbumin glycopeptides containing four to seven mannose residues and bovine lactotransferrin glycopeptides containing four to nine mannose residues were completely hydrolyzed by the enzyme.	Mannose	84-91	ovalbumin	Bos taurus	35-44
2562506-3	1989	The results obtained indicate that ovalbumin glycopeptides containing four to seven mannose residues and bovine lactotransferrin glycopeptides containing four to nine mannose residues were completely hydrolyzed by the enzyme.	Mannose	167-174	ovalbumin	Bos taurus	35-44
2562506-3	1989	The results obtained indicate that ovalbumin glycopeptides containing four to seven mannose residues and bovine lactotransferrin glycopeptides containing four to nine mannose residues were completely hydrolyzed by the enzyme.	Mannose	167-174	lactotransferrin	Bos taurus	112-128
2563273-2	1989	We have investigated the lymphocyte mitogenic activity of this mannose-specific adhesin by comparing the ability of purified wild type type 1 fimbriae containing the adhesin and mutant type 1 fimbriae lacking the adhesin to stimulate proliferation in human lymphocytes.	Mannose	63-70	adhesin	Escherichia coli	166-173
2535487-1	1989	Poly-L-lysine modified with mannose derivatives, the residual cationic charges of which being neutralized by N-acylation, were synthesized and used as carriers of a macrophage activator (N-acetylmuramyl dipeptide, MDP).	Mannose	28-35	dipeptidase 1	Homo sapiens	214-217
2810237-3	1989	The antiluteolytic signal in bovine conceptus secretory proteins (bCSP) is bovine trophoblast protein-1 (bTP-1), a group of 7 isomers of N-linked glycoproteins in two size classes (22,000 high-mannose and 24,000 complex types) that are related immunologically to ovine trophoblast protein-1 (oTP-1).	Mannose	193-200	interferon tau-2	Bos taurus	82-103
2674322-5	1989	The expression of FSHA and MSHA correlated very well with the direct binding of vibrios to fucose- and mannose-coated agarose beads, respectively.	Mannose	103-110	glycoprotein hormones, alpha polypeptide	Homo sapiens	18-22
2494430-4	1989	At least a subset of the N-linked oligosaccharides in extracellular t-PA was resistant to endo-beta-N-acetyl-D-glucosaminidase H, which removes immature, high-mannose-type oligosaccharides.	Mannose	159-166	chromosome 20 open reading frame 181	Homo sapiens	68-72
2535725-5	1989	Pulse-chase studies in EECC-infected cells demonstrated that processing of gp80 to gp70 was delayed and that this retardation of envelope glycoprotein processing could be simulated in 61E-infected cells by treatment with the glucosidase inhibitor N-methyldeoxynojirimycin, a compound that causes retention of oligosaccharides in the high-mannose form.	Mannose	338-345	interleukin 6 receptor	Homo sapiens	75-79
3143729-8	1988	Further, biosynthetically labeled, intracellularly cleaved polypeptides corresponding to the high mannose precursor or mature forms of MGA were not detected.	Mannose	98-105	maltase-glucoamylase	Homo sapiens	135-138
2654926-0	1989	Effects of mannose and fructose on the synthesis and secretion of insulin.	Mannose	11-18	insulin	Homo sapiens	66-73
3142872-8	1988	The association of t-PA with endothelial cells could be inhibited 80% by the mannose-terminated glycoprotein ovalbumin, suggesting that the mannose receptor plays a major role in the recognition of t-PA by endothelial liver cells.	Mannose	77-84	plasminogen activator, tissue type	Rattus norvegicus	19-23
3142872-8	1988	The association of t-PA with endothelial cells could be inhibited 80% by the mannose-terminated glycoprotein ovalbumin, suggesting that the mannose receptor plays a major role in the recognition of t-PA by endothelial liver cells.	Mannose	77-84	plasminogen activator, tissue type	Rattus norvegicus	198-202
3192517-4	1988	Following metabolic labeling with 32P, immunoisolation of the EGF receptor, and digestion with Pronase radioactivity was determined to be present on high mannose type oligosaccharides by concanavalin A chromatography.	Mannose	154-161	epidermal growth factor receptor	Homo sapiens	62-74
2463783-4	1988	On the contrary, human IgM was not bound by this column despite reports that it contains high-mannose type glycan chains.	Mannose	94-101	immunoglobulin heavy constant mu	Mus musculus	23-26
3192517-7	1988	Last, an acid hydrolysate of [3H]mannose-labeled EGF receptor contained two radiolabeled fractions, as analyzed by thin layer electrophoresis, and the radioactivity in one of these fractions was substantially reduced by alkaline phosphatase treatment prior to electrophoresis.	Mannose	33-40	epidermal growth factor receptor	Homo sapiens	49-61
3143483-8	1988	SAP is a glycosylated protein with a high mannose content; therefore mannose and other sugars were tested for inhibition of binding.	Mannose	42-49	amyloid P component, serum	Mus musculus	0-3
2469444-6	1988	These residues may be linked beta 1-2, beta 1-4, or beta 1-6 to one, two, or three different mannose residues.	Mannose	93-100	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	29-37
2469444-6	1988	These residues may be linked beta 1-2, beta 1-4, or beta 1-6 to one, two, or three different mannose residues.	Mannose	93-100	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	39-47
2469444-6	1988	These residues may be linked beta 1-2, beta 1-4, or beta 1-6 to one, two, or three different mannose residues.	Mannose	93-100	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	52-60
3143483-8	1988	SAP is a glycosylated protein with a high mannose content; therefore mannose and other sugars were tested for inhibition of binding.	Mannose	69-76	amyloid P component, serum	Mus musculus	0-3
3143483-9	1988	Specific binding of SAP was inhibited by less than 1 mM concentrations of mannose 6-P, mannose 1-P, and mannose; however, other monosaccharides did not inhibit the binding.	Mannose	74-81	amyloid P component, serum	Mus musculus	20-23
2467679-1	1988	A partial purified polymerase from S. anatum was used for the synthesis of polysaccharide [-6) [14C]Man(beta 1-4)Rha(alpha 1-3)Gal(alpha 1-]n and its analogues containing D-glucose residue instead of D-galactose or D-mannose.	Mannose	215-224	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	104-112
3140897-8	1988	Chemical modification of hexokinase by iodoacetamide in the presence of mannose resulted in the modification of six sulfhydryl groups per mol of hexokinase with retention of the phosphotransferase activity.	Mannose	72-79	hexokinase	Saccharomyces cerevisiae S288C	25-35
3140897-8	1988	Chemical modification of hexokinase by iodoacetamide in the presence of mannose resulted in the modification of six sulfhydryl groups per mol of hexokinase with retention of the phosphotransferase activity.	Mannose	72-79	hexokinase	Saccharomyces cerevisiae S288C	145-155
2977291-4	1988	Lec1 cells form only high mannose-type N-linked oligosaccharides because they lack GlcNAc transferase I activity.	Mannose	26-33	adhesion G protein-coupled receptor L2	Homo sapiens	0-4
2460142-6	1988	PRP contained fucose, mannose, galactose, glucosamine and sialic acid accounting for 8.0% of the dry weight.	Mannose	22-29	complement component 4 binding protein alpha	Homo sapiens	0-3
2467679-1	1988	A partial purified polymerase from S. anatum was used for the synthesis of polysaccharide [-6) [14C]Man(beta 1-4)Rha(alpha 1-3)Gal(alpha 1-]n and its analogues containing D-glucose residue instead of D-galactose or D-mannose.	Mannose	215-224	adrenoceptor alpha 1D	Homo sapiens	117-126
2467679-1	1988	A partial purified polymerase from S. anatum was used for the synthesis of polysaccharide [-6) [14C]Man(beta 1-4)Rha(alpha 1-3)Gal(alpha 1-]n and its analogues containing D-glucose residue instead of D-galactose or D-mannose.	Mannose	215-224	adrenoceptor alpha 1D	Homo sapiens	117-124
3207996-12	1988	Only glucose derivatives with a sufficiently bulky substituent in position C-2, such as the glucokinase substrates glucose and mannose and the inhibitors mannoheptulose, glucosamine, and N-acetylglucosamine, protected glucokinase against inhibition by alloxan by binding to the active site of the enzyme.	Mannose	127-134	glucokinase	Homo sapiens	92-103
3063258-7	1988	In conclusion, CEA appears to be synthesized as a 145 kDa high-mannose immature form, the protein core accounting for about half of its molecular mass.	Mannose	63-70	CEA cell adhesion molecule 3	Homo sapiens	15-18
3052595-7	1988	Insulin also enhanced mannose metabolism.	Mannose	22-29	insulin	Homo sapiens	0-7
3198249-0	1988	Fibronectin: source of mannose in a highly purified respiratory mucin.	Mannose	23-30	fibronectin 1	Homo sapiens	0-11
3049586-1	1988	Purification of the alpha-mannosidase which removes one specific mannose residue from Man9GlcNAc.	Mannose	65-72	alpha-mannosidase	Saccharomyces cerevisiae S288C	20-37
3262613-2	1988	Interleukin 3 (IL-3) derived from mouse T cells was biosynthetically labeled with either [35S]methionine or [3H]mannose, affinity-purified using various anti-IL-3 antibodies, and analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.	Mannose	112-119	interleukin 3	Mus musculus	0-19
3262613-2	1988	Interleukin 3 (IL-3) derived from mouse T cells was biosynthetically labeled with either [35S]methionine or [3H]mannose, affinity-purified using various anti-IL-3 antibodies, and analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.	Mannose	112-119	interleukin 3	Mus musculus	15-19
3198249-0	1988	Fibronectin: source of mannose in a highly purified respiratory mucin.	Mannose	23-30	LOC100508689	Homo sapiens	64-69
3211159-0	1988	Evidence that serum amyloid P component binds to mannose-terminated sequences of polysaccharides and glycoproteins.	Mannose	49-56	amyloid P component, serum	Homo sapiens	14-39
3178837-4	1988	Protein P35 was found to be a Con A-binding protein rich in mannose.	Mannose	60-67	interleukin 12A	Homo sapiens	8-11
3211159-5	1988	SAP did not bind to the alkali-insoluble fraction of zymosan, which is predominantly a glucan polymer, and its binding to zymosan extract which had been absorbed with concanavalin A was markedly reduced, suggesting that mannose residues are involved in the binding of SAP to zymosan.	Mannose	220-227	amyloid P component, serum	Homo sapiens	0-3
3211159-6	1988	We also demonstrated that SAP binds to the glycoproteins ovalbumin, thyroglobulin, beta-glucuronidase and C3bi, which contain mannose-terminated sequences, while it did not bind to native and desialized preparations of ovomucoid, alpha 1-acid glycoprotein and glycophorin, which lack terminal mannose residues.	Mannose	126-133	amyloid P component, serum	Homo sapiens	26-29
3211159-6	1988	We also demonstrated that SAP binds to the glycoproteins ovalbumin, thyroglobulin, beta-glucuronidase and C3bi, which contain mannose-terminated sequences, while it did not bind to native and desialized preparations of ovomucoid, alpha 1-acid glycoprotein and glycophorin, which lack terminal mannose residues.	Mannose	293-300	amyloid P component, serum	Homo sapiens	26-29
3264883-14	1988	All results are consistent with the conclusion that the gp39 molecule is an integral membrane glycoprotein composed of heterogeneous N-linked oligosaccharides of both the complex and high mannose types.	Mannose	188-195	chitinase 3 like 1	Homo sapiens	56-60
2900246-5	1988	The times of maximal labeling of hepatocyte plasma membrane DPP IV were 6-9 min for [3H]L-fucose, 20 min for [3H]D-mannose, and 25 min for [35S]L-methionine.	Mannose	113-122	dipeptidylpeptidase 4	Rattus norvegicus	60-66
3211159-10	1988	These findings indicate that mannose-terminated oligosaccharides of polysaccharides and glycoproteins represent a new class of ligands for SAP and suggest that SAP may function as a mannose-binding protein.	Mannose	29-36	amyloid P component, serum	Homo sapiens	139-142
3211159-10	1988	These findings indicate that mannose-terminated oligosaccharides of polysaccharides and glycoproteins represent a new class of ligands for SAP and suggest that SAP may function as a mannose-binding protein.	Mannose	29-36	amyloid P component, serum	Homo sapiens	160-163
3211159-10	1988	These findings indicate that mannose-terminated oligosaccharides of polysaccharides and glycoproteins represent a new class of ligands for SAP and suggest that SAP may function as a mannose-binding protein.	Mannose	182-189	amyloid P component, serum	Homo sapiens	139-142
3211159-10	1988	These findings indicate that mannose-terminated oligosaccharides of polysaccharides and glycoproteins represent a new class of ligands for SAP and suggest that SAP may function as a mannose-binding protein.	Mannose	182-189	amyloid P component, serum	Homo sapiens	160-163
2847350-0	1988	Tissue plasminogen activator is endocytosed by mannose and galactose receptors of rat liver cells.	Mannose	47-54	plasminogen activator, tissue type	Rattus norvegicus	0-28
3261962-11	1988	Pulse-chase labeling showed that the first detectable form of PPH had a Mr 90,000 which corresponded to the high-mannose precursor as assessed by its sensitivity to endo-beta-N-acetylglucosaminidase H. Within 15 min of chase and prior to complex glycosylation, dimerization due to the formation of interchain disulfide bonds occurred (Mr 180,000).	Mannose	113-120	enolase 1	Homo sapiens	62-65
3403721-3	1988	At least three phenotypes were revealed: one in which sucrase-isomaltase protein accumulated intracellularly probably in the endoplasmic reticulum, as a membrane-associated high-mannose precursor, one in which the intracellular transport of the enzyme was apparently blocked in the Golgi apparatus, and one in which catalytically altered enzyme was transported to the cell surface.	Mannose	178-185	sucrase-isomaltase	Homo sapiens	54-72
2847350-6	1988	Ovalbumin, mannan, mannose, fructose, and EDTA, but not galactose, effectively inhibited uptake in liver endothelial cells of both native and diisopropyl fluorophosphate-inhibited tPA, but had very little effect on the uptake of tPA modified in the carbohydrate side chains.	Mannose	19-26	plasminogen activator, tissue type	Rattus norvegicus	180-183
2847350-6	1988	Ovalbumin, mannan, mannose, fructose, and EDTA, but not galactose, effectively inhibited uptake in liver endothelial cells of both native and diisopropyl fluorophosphate-inhibited tPA, but had very little effect on the uptake of tPA modified in the carbohydrate side chains.	Mannose	19-26	plasminogen activator, tissue type	Rattus norvegicus	229-232
3360775-3	1988	Dinitrophenol-derivatized beta-glucuronidase (DNP-beta-glucuronidase), a ligand for the mannose receptor, was endocytosed by one population of J774 E clone cells, and mannose-derivatized monoclonal anti-DNP IgG (Man-IgG) was internalized by a second set of cells.	Mannose	88-95	glucuronidase, beta	Mus musculus	26-44
2970619-5	1988	Efficient uptake of acid alpha-glucosidase was achieved by using the mannose-6-phosphate receptor on the cell surface as a target for an enzyme precursor with phosphorylated high-mannose types carbohydrate chains purified from human urine.	Mannose	69-76	sucrase-isomaltase	Homo sapiens	25-42
2967294-2	1988	UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I catalyzes an essential first step in the conversion of high mannose to hybrid and complex N-glycans (Schachter, H. (1986) Biochem.	Mannose	147-154	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Oryctolagus cuniculus	0-86
2838571-3	1988	The initial step in gcI synthesis involved the glycosylation of a 95K protein (p95) to form a high-mannose, simple N-linked glycoprotein of Mr 158K (gp158), which was detected only in the presence of the glycoprotein processing inhibitor castanospermine.	Mannose	99-106	nibrin	Homo sapiens	79-82
3360775-3	1988	Dinitrophenol-derivatized beta-glucuronidase (DNP-beta-glucuronidase), a ligand for the mannose receptor, was endocytosed by one population of J774 E clone cells, and mannose-derivatized monoclonal anti-DNP IgG (Man-IgG) was internalized by a second set of cells.	Mannose	88-95	glucuronidase, beta	Mus musculus	50-68
3383434-1	1988	The carbohydrate moiety of human serum amyloid P component was analyzed and found to consist of equal amounts of galactose and mannose (total 4.0%), of glucosamine and galactosamine in a ratio of 7:1 (total 2.7%) and sialic acid (3.9%).	Mannose	127-134	amyloid P component, serum	Homo sapiens	33-58
2835824-4	1988	PGK transformants behaved phenotypically as predicted by the properties of their wild type parent: mannose was no longer toxic, but instead was metabolized via glycolysis to lactic acid, and cell growth was no longer dependent on glutamine oxidation.	Mannose	99-106	phosphoglycerate kinase 1	Cricetulus griseus	0-3
3367907-2	1988	The carbohydrate chains of NB are processed from the high-mannose form (NB18) to a heterogeneous form of much higher molecular weight, designated NBp.	Mannose	58-65	NUBP iron-sulfur cluster assembly factor 1, cytosolic	Homo sapiens	27-29
3127078-6	1988	These findings suggest that mannose/N-acetylglucosamine-specific glycoprotein receptors expressed on hepatic reticuloendothelial cells participate in clearance of t-PA from the circulation but that galactose-specific glycoprotein receptors probably do not.	Mannose	28-35	plasminogen activator, tissue type	Homo sapiens	163-167
3126186-3	1988	On the other hand, carbohydrate processing of beta-galactosidase and beta-glucuronidase was markedly altered by swainsonine, consistent with a blockage by the inhibitor of the removal of the alpha-1,3- and alpha-1,6-linked mannose residues which occurs in normal processing.	Mannose	223-230	galactosidase, beta 1	Mus musculus	46-64
3126186-3	1988	On the other hand, carbohydrate processing of beta-galactosidase and beta-glucuronidase was markedly altered by swainsonine, consistent with a blockage by the inhibitor of the removal of the alpha-1,3- and alpha-1,6-linked mannose residues which occurs in normal processing.	Mannose	223-230	glucuronidase, beta	Mus musculus	69-87
3346233-9	1988	The Man8GlcNAc isomer produced by endomannosidase action was found to be processed by Golgi enzymes through a different sequence of intermediates than the rough endoplasmic reticulum-generated Man8GlcNAc variant, in which the terminal mannose of the middle branch is absent.	Mannose	235-242	mannosidase endo-alpha	Homo sapiens	34-49
3346233-10	1988	Whereas the latter oligosaccharide is converted to Man5GlcNAc via Man7GlcNAc and Man6GlcNAc at an even rate, the processing of the endomannosidase-derived Man8GlcNAc stalls at the Man6GlcNAc stage due to the apparent resistance to Golgi mannosidase I of the alpha 1,2-linked mannose of the middle branch.	Mannose	275-282	mannosidase endo-alpha	Homo sapiens	131-146
2450948-4	1988	This human mannose-binding protein bears 51% overall homology (allowing three gaps) with a rat mannose-binding protein C and 48% homology (allowing seven gaps) with a rat mannose-binding protein A.	Mannose	11-18	mannose binding lectin 2	Rattus norvegicus	95-120
2450948-4	1988	This human mannose-binding protein bears 51% overall homology (allowing three gaps) with a rat mannose-binding protein C and 48% homology (allowing seven gaps) with a rat mannose-binding protein A.	Mannose	11-18	mannose binding lectin 1	Rattus norvegicus	171-196
3355864-2	1988	High-mannose precursors of Mr = 30,000 and 34,000 comprised a significant fraction of intracellular SP-A in vivo and in vitro.	Mannose	5-12	surfactant protein A1	Rattus norvegicus	100-104
3355864-6	1988	In the presence of either alpha,alpha"-dipyridyl or cis-4-hydroxy-L-proline, high mannose precursors accumulated intracellularly and were not secreted after 16-18 h. Thus, high-mannose precursors in proximal intracellular pool(s) and sialylated forms in lamellar body-enriched fractions represent two major intracellular storage forms of SP-A in vitro and in vivo.	Mannose	82-89	surfactant protein A1	Rattus norvegicus	338-342
3355864-6	1988	In the presence of either alpha,alpha"-dipyridyl or cis-4-hydroxy-L-proline, high mannose precursors accumulated intracellularly and were not secreted after 16-18 h. Thus, high-mannose precursors in proximal intracellular pool(s) and sialylated forms in lamellar body-enriched fractions represent two major intracellular storage forms of SP-A in vitro and in vivo.	Mannose	177-184	surfactant protein A1	Rattus norvegicus	338-342
3345516-9	1988	The binding of SBA to the cell was reduced by preincubation of the lectin with galactose, completely blocked by incubation with N-acetylgalactosamine, and unaffected by incubation with glucose or mannose, demonstrating that SBA was recognizing a N-acetylgalactosamine-containing component of the cell surface.	Mannose	196-203	lectin	Glycine max	15-18
2907838-7	1988	In contrast, human prostatic acid phosphatase, a glycoprotein with a high content of mannose, hybrid and complex oligosaccharides is completely deglycosylated under identical experimental conditions.	Mannose	85-92	acid phosphatase 3	Homo sapiens	19-45
3339713-2	1988	Pulse-chase, tunicamycin treatment, and carbohydrate trimming experiments revealed that VGF is synthesized as a 19-kilodalton (kDa) precursor which is rapidly modified to a high-mannose-type 22-kDa protein.	Mannose	178-185	VGF nerve growth factor inducible	Homo sapiens	88-91
2893745-3	1988	Castanospermine, an inhibitor of glucosidase I, induced a high mannose-glycosylated form of microvillar aminopeptidase N (EC 3.4.11.2) of increased molecular mass, indicating the blocked removal of glucose residues.	Mannose	63-70	aminopeptidase N	Oryctolagus cuniculus	104-120
2893745-6	1988	240, 777-782], this molecular form of aminopeptidase N was at least as abundant in cell-free translation as its normal high mannose-glycosylated counterpart, ruling out degradation taking place in the rough endoplasmic reticulum.	Mannose	124-131	aminopeptidase N	Oryctolagus cuniculus	38-54
2456179-9	1988	Later, the yolk granules, which contain vitellogenin synthesized in the liver and taken up from the plasma, show a clear affinity for con A. Con A staining disappears when mannopyranoside is added.	Mannose	172-187	vitellogenin	Gasterosteus aculeatus	40-52
2449168-0	1987	The role of C-4-substituted mannose analogues in protein glycosylation.	Mannose	28-35	complement C4A (Rodgers blood group)	Homo sapiens	12-15
2970569-6	1988	Incorporation studies with labelled leucine and mannose showed that the inhibitor did not significantly affect protein synthesis, but it did inhibit mannose incorporation into AGP and sialyltransferase.	Mannose	48-55	orosomucoid 1	Rattus norvegicus	176-179
2970569-6	1988	Incorporation studies with labelled leucine and mannose showed that the inhibitor did not significantly affect protein synthesis, but it did inhibit mannose incorporation into AGP and sialyltransferase.	Mannose	149-156	orosomucoid 1	Rattus norvegicus	176-179
3354262-6	1988	Acid-stable, heat-stable polypeptides of bovine milk had the lowest carbohydrate content (4 mg/100 mg protein), whereas the highest content was found in ewe"s milk (7.30 mg/100 mg protein) mainly as a result of the high galactose, mannose and glucosamine content.	Mannose	231-238	Weaning weight-maternal milk	Bos taurus	48-52
2891709-9	1988	Additional experiments were performed to determine the electrophoretic mobility and hydrophobicity of cell-associated and released forms of Thy-1 labeled overnight with [3H]mannose.	Mannose	173-180	Thy-1 cell surface antigen	Homo sapiens	140-145
2445475-4	1987	These and other properties indicate the gp90 carries mainly high mannose or hybrid N-linked carbohydrate chains.	Mannose	65-72	galectin 3 binding protein	Homo sapiens	40-44
3674885-1	1987	A high-molecular-weight mucin-glycoprotein (MG1) was isolated from human submandibular-sublingual saliva and was comprised of 14.9% protein, 29.0% N-acetylglucosamine, 9.4% N-acetylgalactosamine, 10.5% fucose, 24.2% galactose, 0.9% mannose, 4.0% N-acetylneuraminic acid, and 7.0% sulfate.	Mannose	232-239	LOC100508689	Homo sapiens	24-29
3442689-4	1987	The monosaccharides glucose, fructose, and mannose and the nonmetabolizable sugars 2-deoxyglucose and sucrose inhibited the enhancement of Ca2+-permeability.	Mannose	43-50	LOW QUALITY PROTEIN: carbonic anhydrase 2	Cavia porcellus	139-142
3321055-1	1987	The yeast Saccharomyces cerevisiae X2180 strain with the mnn1 mnn2 mnn9 mutations, all of which affect mannoprotein glycosylation, synthesizes N-linked oligosaccharides having the following structure: (Formula: see text) whereas the mnn1 mnn2 mutant extends the alpha 1----6-linked backbone of some of the core oligosaccharides by adding 20-30 mannose units.	Mannose	344-351	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	57-66
3321055-1	1987	The yeast Saccharomyces cerevisiae X2180 strain with the mnn1 mnn2 mnn9 mutations, all of which affect mannoprotein glycosylation, synthesizes N-linked oligosaccharides having the following structure: (Formula: see text) whereas the mnn1 mnn2 mutant extends the alpha 1----6-linked backbone of some of the core oligosaccharides by adding 20-30 mannose units.	Mannose	344-351	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	57-61
3674885-1	1987	A high-molecular-weight mucin-glycoprotein (MG1) was isolated from human submandibular-sublingual saliva and was comprised of 14.9% protein, 29.0% N-acetylglucosamine, 9.4% N-acetylgalactosamine, 10.5% fucose, 24.2% galactose, 0.9% mannose, 4.0% N-acetylneuraminic acid, and 7.0% sulfate.	Mannose	232-239	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	44-47
3667605-7	1987	The latter released a water-soluble mannose-labeled moiety which eluted from Bio-Gel P-6 in a manner similar to Glc3Man9GlcNAc2.	Mannose	36-43	exosome component 9	Homo sapiens	85-88
3321055-2	1987	Membrane fractions from the mnn1 mnn2 and mnn1 mnn2 mnn9 mutants are equally effective in catalyzing transfer from GDP-[3H]mannose to add mannose in both alpha 1----2 and alpha 1----6 linkages to an oligosaccharide having the following structure: (Formula: see text) but neither membrane preparation can utilize the homologous mnn1 mnn2 mnn9 oligosaccharide as an acceptor.	Mannose	123-130	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	28-32
3321055-2	1987	Membrane fractions from the mnn1 mnn2 and mnn1 mnn2 mnn9 mutants are equally effective in catalyzing transfer from GDP-[3H]mannose to add mannose in both alpha 1----2 and alpha 1----6 linkages to an oligosaccharide having the following structure: (Formula: see text) but neither membrane preparation can utilize the homologous mnn1 mnn2 mnn9 oligosaccharide as an acceptor.	Mannose	123-130	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	33-37
3321055-2	1987	Membrane fractions from the mnn1 mnn2 and mnn1 mnn2 mnn9 mutants are equally effective in catalyzing transfer from GDP-[3H]mannose to add mannose in both alpha 1----2 and alpha 1----6 linkages to an oligosaccharide having the following structure: (Formula: see text) but neither membrane preparation can utilize the homologous mnn1 mnn2 mnn9 oligosaccharide as an acceptor.	Mannose	123-130	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	42-46
3321055-2	1987	Membrane fractions from the mnn1 mnn2 and mnn1 mnn2 mnn9 mutants are equally effective in catalyzing transfer from GDP-[3H]mannose to add mannose in both alpha 1----2 and alpha 1----6 linkages to an oligosaccharide having the following structure: (Formula: see text) but neither membrane preparation can utilize the homologous mnn1 mnn2 mnn9 oligosaccharide as an acceptor.	Mannose	123-130	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	47-56
3321055-2	1987	Membrane fractions from the mnn1 mnn2 and mnn1 mnn2 mnn9 mutants are equally effective in catalyzing transfer from GDP-[3H]mannose to add mannose in both alpha 1----2 and alpha 1----6 linkages to an oligosaccharide having the following structure: (Formula: see text) but neither membrane preparation can utilize the homologous mnn1 mnn2 mnn9 oligosaccharide as an acceptor.	Mannose	123-130	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	28-37
2820530-4	1987	Endoglycosidase H and F digestion of immunoprecipitated pro-MPO demonstrated the presence of five N-linked--high-mannose oligosaccharide side chains and no complex mannose units.	Mannose	113-120	myeloperoxidase	Homo sapiens	60-63
3498532-5	1987	Hepatic uptake is dependent upon Kupffer cell recognition of mannose-containing oligosaccharide structures on the RTA moiety of immunotoxin.	Mannose	61-68	MAS related GPR family member F	Homo sapiens	114-117
3498532-6	1987	Mannose-containing blocking agents given with immunotoxin were shown to prolong circulation time of the immunotoxin in blood including those species with higher RTA-monoclonal antibody ratios and reduce liver uptake.	Mannose	0-7	MAS related GPR family member F	Homo sapiens	161-164
3620482-2	1987	One mannose-binding protein (MBP 1) has a native Mr of 700,000 with subunits of Mr 32,000 and has specificities for N-acetylglucosamine, N-acetylmannosamine and glucose as well as for mannose and fucose.	Mannose	4-11	mannose binding lectin 2	Homo sapiens	29-34
2959666-10	1987	Biochemical analysis of the internalized ligands indicates that: (a) the subunit molecular mass of both beta-glucuronidase and beta-galactosidase decrease upon cell association relative to the input form of the enzymes, and (b) the beta-glucuronidase molecules experience a limited dephosphorylation such that high-mannose-type oligosaccharides containing two phosphomonoesters are converted to single phosphomonoester forms.	Mannose	315-322	glucuronidase beta	Homo sapiens	104-122
2959666-10	1987	Biochemical analysis of the internalized ligands indicates that: (a) the subunit molecular mass of both beta-glucuronidase and beta-galactosidase decrease upon cell association relative to the input form of the enzymes, and (b) the beta-glucuronidase molecules experience a limited dephosphorylation such that high-mannose-type oligosaccharides containing two phosphomonoesters are converted to single phosphomonoester forms.	Mannose	315-322	galactosidase beta 1	Homo sapiens	127-145
2959666-10	1987	Biochemical analysis of the internalized ligands indicates that: (a) the subunit molecular mass of both beta-glucuronidase and beta-galactosidase decrease upon cell association relative to the input form of the enzymes, and (b) the beta-glucuronidase molecules experience a limited dephosphorylation such that high-mannose-type oligosaccharides containing two phosphomonoesters are converted to single phosphomonoester forms.	Mannose	315-322	glucuronidase beta	Homo sapiens	232-250
2891508-5	1987	The intracellular pool size of the transient, high mannose glycosylated form of aminopeptidase N was unaffected by forskolin, indicating a normal synthesis in the rough endoplasmic reticulum.	Mannose	51-58	alanyl aminopeptidase, membrane	Sus scrofa	80-96
3620482-2	1987	One mannose-binding protein (MBP 1) has a native Mr of 700,000 with subunits of Mr 32,000 and has specificities for N-acetylglucosamine, N-acetylmannosamine and glucose as well as for mannose and fucose.	Mannose	184-191	mannose binding lectin 2	Homo sapiens	29-34
3620482-3	1987	The other mannose-binding protein (MBP 2) has a native Mr of 200,000 with subunits of Mr 28,000 and is specific only for mannose and fucose.	Mannose	10-17	HIVEP zinc finger 2	Homo sapiens	35-40
3620482-3	1987	The other mannose-binding protein (MBP 2) has a native Mr of 200,000 with subunits of Mr 28,000 and is specific only for mannose and fucose.	Mannose	121-128	HIVEP zinc finger 2	Homo sapiens	35-40
3676256-3	1987	The delipidated high-density product obtained had a nominal molecular weight of about 10(6) and an overall composition characteristic for a mucin glycoprotein, viz., a high content of serine and threonine, about 80% carbohydrate by weight, the absence of mannose or uronic acid, measurable ester sulfate, and a Pronase-resistant domain of molecular weight (1.75-3.0) X 10(5) which contains essentially all of the saccharide residues.	Mannose	255-262	mucin	Canis lupus familiaris	140-145
3440085-4	1987	In the mutant designated D-1, which has a defect in dolichol mannosyl transferase, both mannose incorporation into gp46 and ConA binding to gp46 was reduced compared with L6, without markedly affecting the gelatin adhesion properties of gp46.	Mannose	88-95	serpin family H member 1	Rattus norvegicus	115-119
3305746-0	1987	Macrophage migration inhibition induced by MDP, LPS, PMA, and MIF/MAF: reversal by macrophage migration enhancement factor (MEF), L-fucose, L-fucosyl BSA, D-mannose, and D-mannosyl BSA.	Mannose	155-164	macrophage migration inhibitory factor	Homo sapiens	62-65
3305746-0	1987	Macrophage migration inhibition induced by MDP, LPS, PMA, and MIF/MAF: reversal by macrophage migration enhancement factor (MEF), L-fucose, L-fucosyl BSA, D-mannose, and D-mannosyl BSA.	Mannose	155-164	MAF bZIP transcription factor	Homo sapiens	66-69
3113515-4	1987	The PAI-1 could not be removed by incubating ECM in high salt (2 mol/L NaCl), sugars (1 mol/L galactose, 1 mol/L mannose), glycosaminoglycans (10 mmol/L heparin, 10 mmol/L dermatan sulfate), or epsilon-aminocaproic acid (0.1 mol/L).	Mannose	113-120	serpin family E member 1	Bos taurus	4-9
3305746-2	1987	The monosaccharides L-fucose and D-mannose were also shown to reverse MIF and additionally to stimulate alveolar macrophage (AM) migration in the absence of MIF.	Mannose	33-42	macrophage migration inhibitory factor	Homo sapiens	70-73
3305746-2	1987	The monosaccharides L-fucose and D-mannose were also shown to reverse MIF and additionally to stimulate alveolar macrophage (AM) migration in the absence of MIF.	Mannose	33-42	macrophage migration inhibitory factor	Homo sapiens	157-160
3305746-6	1987	It was found that L-fucose, D-mannose, L-fucosyl BSA, and D-mannosyl BSA could reverse migration inhibition caused by MIF as well as by these metabolic activators.	Mannose	28-37	macrophage migration inhibitory factor	Homo sapiens	118-121
2960375-6	1987	Methylation analysis and enzymatic digestions showed that both terminal GlcNAc residues on (GlcNAc)2Man3GlcNAc were attached to the mannoses in beta 1,2 linkages.	Mannose	132-140	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	144-152
2885431-1	1987	Uropathogenic E. coli that express mannose sensitive adhesins adhere to agglutinated urinary Tamm-Horsfall protein (THP) and to exfoliated transitional epithelial cells coated with THP.	Mannose	35-42	uromodulin	Homo sapiens	116-119
3301851-9	1987	GnRH decreases [2-3H]mannose incorporation into secreted rLH.	Mannose	21-28	gonadotropin releasing hormone 1	Rattus norvegicus	0-4
3620493-2	1987	We show here that ASF-like proteins are produced in the rat during intestinal secretion triggered by intake of a 500 mg dose of mannose, sorbitol, glycine or alanine.	Mannose	128-135	proteasome 26S subunit ubiquitin receptor, non-ATPase 4	Rattus norvegicus	18-21
2885431-1	1987	Uropathogenic E. coli that express mannose sensitive adhesins adhere to agglutinated urinary Tamm-Horsfall protein (THP) and to exfoliated transitional epithelial cells coated with THP.	Mannose	35-42	uromodulin	Homo sapiens	181-184
2440862-5	1987	Approximately one-half of the phosphate in FRTL-5 cell or bovine thyroglobulin can also be released by enzymatic deglycosylation and can be located in Pronase-digested peptides which contain mannose, are endo-beta-N-acetylglucosaminidase H but not neuraminidase-sensitive, and release a dually labeled oligosaccharide containing mannose and phosphate after endo-beta-N-acetylglucosaminidase H digestion.	Mannose	191-198	thyroglobulin	Bos taurus	65-78
3497198-1	1987	The site-specific glycosylation patterns of two H-2K alleles, k and b, were determined on splenic T cells metabolically labeled with [3H]mannose.	Mannose	137-144	histocompatibility 2, K1, K region	Mus musculus	48-52
2440862-5	1987	Approximately one-half of the phosphate in FRTL-5 cell or bovine thyroglobulin can also be released by enzymatic deglycosylation and can be located in Pronase-digested peptides which contain mannose, are endo-beta-N-acetylglucosaminidase H but not neuraminidase-sensitive, and release a dually labeled oligosaccharide containing mannose and phosphate after endo-beta-N-acetylglucosaminidase H digestion.	Mannose	329-336	thyroglobulin	Bos taurus	65-78
3499144-9	1987	The intracellular form of alpha 1-inhibitor3, with an apparent Mr of 173,000, is characterized by oligosaccharide side chains of the high-mannose type.	Mannose	138-145	alpha-1-inhibitor III	Rattus norvegicus	26-44
3611070-7	1987	This binding can be inhibited with EDTA, mannose, fucose, mannan, beta-glucuronidase, and bovine serum albumin conjugated to fucose.	Mannose	41-48	albumin	Homo sapiens	97-110
3499144-11	1987	After labelling hepatocytes with radioactive sugars, [3H]mannose was found in both forms of alpha 1-inhibitor3, whereas [3H]fucose and [3H]galactose were incorporated only into the form found in the medium.	Mannose	57-64	alpha-1-inhibitor III	Rattus norvegicus	92-110
3611196-7	1987	The two major glycoprotein families (DGI and DGII/III) were both found to be synthesized with co-translational addition of 2-4 high mannose cores later processed into complex type chains.	Mannose	132-139	desmoglein 1	Bos taurus	37-40
3664521-1	1987	The capsular polysaccharide from Klebsiella Serotype K40 contains D-galactose, D-mannose, L-rhamnose, and D-glucuronic acid in the ratios of 4:1:1:1.	Mannose	79-88	keratin 40	Homo sapiens	53-56
3584121-1	1987	Serum mannan-binding protein (MBP), a lectin specific for mannose and N-acetylglucosamine, was revealed to activate the complement system as measured by passive hemolysis using sheep erythrocytes coated with yeast mannan.	Mannose	58-65	myelin basic protein	Ovis aries	6-28
3584121-1	1987	Serum mannan-binding protein (MBP), a lectin specific for mannose and N-acetylglucosamine, was revealed to activate the complement system as measured by passive hemolysis using sheep erythrocytes coated with yeast mannan.	Mannose	58-65	myelin basic protein	Ovis aries	30-33
3108266-10	1987	The GPIIb precursor is then processed with conversion of high-mannose to complex type carbohydrates yielding the mature subunits GPIIb alpha (Mr 116,000) and GPIIb beta (Mr 25,000).	Mannose	62-69	integrin subunit alpha 2b	Homo sapiens	4-9
3108266-10	1987	The GPIIb precursor is then processed with conversion of high-mannose to complex type carbohydrates yielding the mature subunits GPIIb alpha (Mr 116,000) and GPIIb beta (Mr 25,000).	Mannose	62-69	integrin subunit alpha 2b	Homo sapiens	129-134
3108266-10	1987	The GPIIb precursor is then processed with conversion of high-mannose to complex type carbohydrates yielding the mature subunits GPIIb alpha (Mr 116,000) and GPIIb beta (Mr 25,000).	Mannose	62-69	integrin subunit alpha 2b	Homo sapiens	129-134
3296598-7	1987	Glucokinase activity was protected from alloxan toxicity only by D-glucose and D-mannose; the alpha anomer of D-glucose provided significantly greater protection than the beta anomer.	Mannose	79-88	glucokinase	Rattus norvegicus	0-11
3568359-2	1987	In the presence of D-mannose, glucose can be accurately measured by either the hexokinase procedure or the glucose oxidase procedure.	Mannose	19-28	hexokinase 1	Homo sapiens	79-89
3296597-6	1987	The result showed that insulin, 200 mU/l, induced a shift in composition of neutral sugars by decreasing the amount of galactose relative to glucose and mannose.	Mannose	153-160	insulin	Homo sapiens	23-30
3104329-8	1987	TRH caused a 2-fold increase in secretion of [3H]mannose-labeled TSH glycopeptides due almost exclusively to a specific increase in structures that bound to ConA-Sepharose and eluted with 10mM alpha-methylglucoside, corresponding to biantennary complex or unusual hybrid species.	Mannose	49-56	thyrotropin releasing hormone	Mus musculus	0-3
3818665-3	1987	The endomannosidase was fully active in the presence of 1-deoxynojirimycin and EDTA which inhibited exoglycosidase release of glucose and mannose, respectively, and these agents were, therefore, included in the standard assay.	Mannose	138-145	mannosidase endo-alpha	Homo sapiens	4-19
2881925-5	1987	In the wild-type cells, Thy-1 can be labeled with [3H] mannose, [3H]galactose, [3H]fucose, [3H]ethanolamine, and [3H]palmitic acid.	Mannose	55-62	Thy-1 cell surface antigen	Homo sapiens	24-29
3803395-1	1987	The capsular polysaccharide of Klebsiella serotype K40 contained D-mannose, D-glucuronic acid, D-galactose, and L-rhamnose in the approximate molar ratios 1:1:1:2.	Mannose	65-74	keratin 40	Homo sapiens	51-54
3816803-4	1987	The results show that the N-linked carbohydrate chains of colligin are exclusively the high-mannose type, of which (Man)8(GlcNAc)2 and (Man)9(GlcNAc)2 make up 77%.	Mannose	92-99	serine (or cysteine) peptidase inhibitor, clade H, member 1	Mus musculus	58-66
3109375-7	1987	Pulse-chase analysis indicated a slow post-translational processing of the high mannose precursor (Mr 215,000) to yield the mature brush-border form (Mr 160,000) of LPH.	Mannose	80-87	lactase	Homo sapiens	165-168
3801415-5	1986	SGP-2 was shown to be 23.7% carbohydrate and consisted of 1% fucose, 3.5% mannose, 4.1% galactose, 7.1% N-acetylglucosamine, and 8.0% N-acetylneuraminic acid.	Mannose	74-81	clusterin	Homo sapiens	0-5
3479094-0	1987	Stimulation of mannose incorporation into rat osteoblastic osteosarcoma cells by parathyroid hormone.	Mannose	15-22	parathyroid hormone	Rattus norvegicus	81-100
3309140-1	1987	The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not.	Mannose	454-461	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	4-9
3551999-7	1986	Sulfation and phosphorylation occurred on POMC within 5 min after its synthesis and were concomitant with the processing of the N-linked carbohydrates from the high mannose to the complex structure.	Mannose	165-172	proopiomelanocortin	Rattus norvegicus	42-46
3780745-2	1986	When the cells were incubated with either [3H]mannose, [3H]galactose, or [3H]fucose, all the radioactive precursors were incorporated into the beta subunit of haptoglobin.	Mannose	46-53	haptoglobin	Homo sapiens	159-170
3780745-3	1986	[3H]Mannose-labeled haptoglobin was purified from the culture medium by immunoaffinity chromatography, and [3H]oligosaccharides were prepared by strong alkali-borohydride treatment.	Mannose	4-11	haptoglobin	Homo sapiens	20-31
3315863-7	1987	Human alpha-AT secreted into the culture broth contains, in addition to core carbohydrate, variable numbers of mannose outer chains, typical of secreted yeast proteins such as invertase.	Mannose	111-118	serpin family A member 1	Homo sapiens	6-14
3032924-1	1987	cDNA clones encoding rat liver mannan-binding protein (MBP), a lectin specific for mannose and N-acetylglucosamine, were isolated from a rat liver cDNA library carried in lambda gt 11, by screening with affinity purified polyclonal rabbit anti-rat liver MBP antibodies.	Mannose	83-90	mannose binding lectin 1	Rattus norvegicus	31-53
3032924-1	1987	cDNA clones encoding rat liver mannan-binding protein (MBP), a lectin specific for mannose and N-acetylglucosamine, were isolated from a rat liver cDNA library carried in lambda gt 11, by screening with affinity purified polyclonal rabbit anti-rat liver MBP antibodies.	Mannose	83-90	mannose binding lectin 1	Rattus norvegicus	55-58
3305909-9	1987	Insulin proreceptor, a 210 kDa high-mannose glycopolypeptide, acquires insulin binding function (t1/2 approximately equal to 45 min) then is proteolytically cleaved (t1/2 approximately equal to 3 hr) into subunits of the mature alpha 2 beta 2 receptor.	Mannose	36-43	insulin	Homo sapiens	0-7
3536911-5	1986	The equatorial hydroxyl groups on the C-3 and C-4 of the mannose ring are important in the lectin-ligand interaction, and the axial hydroxyl group on the C-2 contributes to a lesser extent.	Mannose	57-64	complement C3	Rattus norvegicus	38-41
3536911-5	1986	The equatorial hydroxyl groups on the C-3 and C-4 of the mannose ring are important in the lectin-ligand interaction, and the axial hydroxyl group on the C-2 contributes to a lesser extent.	Mannose	57-64	complement C4A	Rattus norvegicus	46-49
3827834-6	1986	Mannose, galactose, glucosamine and galactosamine represent 17%, 21%, 24% and 10% respectively of the sugar content of GPIIb.	Mannose	0-7	integrin subunit alpha 2b	Homo sapiens	119-124
3827820-1	1986	The insulin receptor is synthesized as a 190,000-Mr single-chain precursor that contains exclusively asparagine-N-linked high-mannose-type carbohydrate chains.	Mannose	126-133	insulin receptor	Homo sapiens	4-20
3827820-9	1986	The mature alpha- and beta-subunits of the insulin receptor are known to contain both high-mannose-type and complex-type oligosaccharides.	Mannose	91-98	insulin receptor	Homo sapiens	43-59
3021061-0	1986	Stimulation by dolichol phosphate-mannose of N-acetylglucosaminyl-lipid biosynthesis by membranes from class E Thy-1-negative mutant mouse lymphoma cells which are defective in dolichol phosphate-mannose biosynthesis.	Mannose	34-41	thymus cell antigen 1, theta	Mus musculus	111-116
3818580-2	1986	Compositional analyses of the purified glycoproteins showed that GPIIb and GPIIIa contain 15% and 18% carbohydrate by weight, respectively, which consists of galactose, mannose, glucosamine, fucose, and sialic acid.	Mannose	169-176	integrin subunit alpha 2b	Homo sapiens	65-70
3818580-2	1986	Compositional analyses of the purified glycoproteins showed that GPIIb and GPIIIa contain 15% and 18% carbohydrate by weight, respectively, which consists of galactose, mannose, glucosamine, fucose, and sialic acid.	Mannose	169-176	integrin subunit beta 3	Homo sapiens	75-81
3818580-7	1986	The neutral oligosaccharides, which comprised about 14% of the total oligosaccharides released from GPIIb and about 52% of that from GPIIIa, were found to be of the high mannose-type, in that they contained 5 or 6 mannose residues.	Mannose	170-177	integrin subunit alpha 2b	Homo sapiens	100-105
3818580-7	1986	The neutral oligosaccharides, which comprised about 14% of the total oligosaccharides released from GPIIb and about 52% of that from GPIIIa, were found to be of the high mannose-type, in that they contained 5 or 6 mannose residues.	Mannose	170-177	integrin subunit beta 3	Homo sapiens	133-139
3821722-5	1986	Uteroferrin, as purified from uterine secretions of pigs, possesses mainly high mannose (predominantly Man5 and Man6) chains.	Mannose	80-87	acid phosphatase 5, tartrate resistant	Sus scrofa	0-11
3771529-15	1986	The PN-I precursor was also sensitive to endoglycosidase H, suggesting that it contains N-linked carbohydrates of the high mannose form.	Mannose	123-130	serpin family E member 2	Homo sapiens	4-8
3096320-1	1986	Mannose toxicity in honeybees is due to a marked shortage of mannosephosphate isomerase that leads to a large accumulation of mannose-6-P and a marked depletion of ATP.	Mannose	0-7	mannose-6-phosphate isomerase	Ceratitis capitata	61-87
3021451-8	1986	This result indicates that part of 5"-nucleotidase keeps one or two high-mannose or hybrid chains in the mature form, even after prolonged pulse-chase labeling.	Mannose	73-80	5' nucleotidase, ecto	Rattus norvegicus	35-50
3530846-4	1986	Inactivation of purified glucokinase was antagonized by glucose, mannose, and 2-deoxyglucose in order of decreasing potency but not by 3-O-methylglucose.	Mannose	65-72	glucokinase	Rattus norvegicus	25-36
3530846-8	1986	The finding that glucokinase is inactivated by alloxan and protected by glucose with discrimination of its anomers similar to inhibition of glucose-stimulated insulin secretion by alloxan supports this hypothesis and appears to explain the mechanism for inhibition of hexose-stimulated insulin secretion by this agent and the unique role of glucose and mannose as protecting agents.	Mannose	353-360	glucokinase	Rattus norvegicus	17-28
3818560-3	1986	Compositional analysis showed that GPIV contains large amounts of acidic and hydroxy amino acids, but only very small amounts of cystine and methionine, and 28.1% (w/w) carbohydrate consisting of galactose, glucosamine, and sialic acid as the principal sugars with smaller amounts of fucose, mannose, and galactosamine.	Mannose	292-299	CD36 molecule	Homo sapiens	35-39
3463967-9	1986	The beta-glucuronidase cDNA will provide a useful tool to study the mechanism of mannose phosphorylation and other aspects of the sorting of lysosomal enzymes to lysosomes.	Mannose	81-88	glucuronidase, beta	Rattus norvegicus	4-22
3092742-4	1986	High resolution gel filtration on TSK HW-40(S) resolved the neutral high mannose population into species of the type Man9-5 N-acetylglucosamine.	Mannose	73-80	tsukushi, small leucine rich proteoglycan	Homo sapiens	34-37
3091101-9	1986	Ratios of radiolabeled mannose/methionine demonstrate a 7-fold greater mannose content in the cellular precursor of beta-galactosidase than in total protein.	Mannose	23-30	galactosidase, beta 1	Rattus norvegicus	116-134
3557071-7	1986	Gas-liquid chromatographic analysis of teleocalcin demonstrated that mannose was the principal sugar present (1.86%) and glucosamine was the only hexosamine identified (2.49%).	Mannose	69-76	stanniocalcin	Oncorhynchus mykiss	39-50
2944109-4	1986	The apparent molecular mass of opsin was increased by approximately 2500 in the presence of Cas; the incorporation of [3H]mannose into opsin was enhanced about 2.3-fold without a significant effect on [14C]leucine incorporation, relative to controls.	Mannose	122-129	rhodopsin, gene2 L homeolog	Xenopus laevis	31-36
2944109-4	1986	The apparent molecular mass of opsin was increased by approximately 2500 in the presence of Cas; the incorporation of [3H]mannose into opsin was enhanced about 2.3-fold without a significant effect on [14C]leucine incorporation, relative to controls.	Mannose	122-129	rhodopsin, gene2 L homeolog	Xenopus laevis	135-140
3789744-1	1986	Mannose-labeled epiglycanin was prepared by incubation of TA3-Ha ascites cells with [2-3H]mannose, removal of the epiglycanin by incubation of viable cells with L-1-p-tosylamino-2-phenylethyl chloromethyl ketone-trypsin, and isolation of the large epiglycanin glycopeptides by gel filtration.	Mannose	0-7	mucin 21	Mus musculus	16-27
3789744-1	1986	Mannose-labeled epiglycanin was prepared by incubation of TA3-Ha ascites cells with [2-3H]mannose, removal of the epiglycanin by incubation of viable cells with L-1-p-tosylamino-2-phenylethyl chloromethyl ketone-trypsin, and isolation of the large epiglycanin glycopeptides by gel filtration.	Mannose	0-7	mucin 21	Mus musculus	114-125
3789744-1	1986	Mannose-labeled epiglycanin was prepared by incubation of TA3-Ha ascites cells with [2-3H]mannose, removal of the epiglycanin by incubation of viable cells with L-1-p-tosylamino-2-phenylethyl chloromethyl ketone-trypsin, and isolation of the large epiglycanin glycopeptides by gel filtration.	Mannose	0-7	mucin 21	Mus musculus	114-125
3789744-10	1986	Incubation of nonlabeled epiglycanin under similar conditions with the same enzyme preparation followed by passage through Column P-4, gave two peaks, based upon total mannose content.	Mannose	168-175	mucin 21	Mus musculus	25-36
3789744-12	1986	Its composition indicated that approximately 80% of the mannose content of epiglycanin had been removed by the enzyme treatment, whereas no change was noted in the proportion of the other carbohydrate components.	Mannose	56-63	mucin 21	Mus musculus	75-86
3827834-5	1986	Mannose, galactose and glucosamine account for 45%, 13% and 28% respectively of the sugars of GPIIIa, whereas galactosamine was not detected.	Mannose	0-7	integrin subunit beta 3	Homo sapiens	94-100
3091101-9	1986	Ratios of radiolabeled mannose/methionine demonstrate a 7-fold greater mannose content in the cellular precursor of beta-galactosidase than in total protein.	Mannose	71-78	galactosidase, beta 1	Rattus norvegicus	116-134
3091101-12	1986	Ratios of radiolabeled mannose/methionine in the cellular precursor of beta-glucuronidase are 2-fold greater than ratios in the total glycoprotein.	Mannose	23-30	glucuronidase, beta	Rattus norvegicus	71-89
2941420-9	1986	Apo(a) contained 28.1% carbohydrate by weight represented by mannose, galactose, galactosamine, glucosamine, and sialic acid in an approximate molar ratio of 3:7:5:4:7, respectively.	Mannose	61-68	lipoprotein(a)	Homo sapiens	0-6
2426082-10	1986	TSH secreted in the presence of TRH had a lower sulfate to mannose ratio [28 +/- (+/- SE) 4% of control; P less than 0.05] and a lower sialic acid to mannose ratio (63 +/- 8% of control; P less than 0.05).	Mannose	59-66	thyrotropin releasing hormone	Mus musculus	32-35
2426082-10	1986	TSH secreted in the presence of TRH had a lower sulfate to mannose ratio [28 +/- (+/- SE) 4% of control; P less than 0.05] and a lower sialic acid to mannose ratio (63 +/- 8% of control; P less than 0.05).	Mannose	150-157	thyrotropin releasing hormone	Mus musculus	32-35
3461457-10	1986	The FA-1 revealed a positive reaction with periodic-Schiff reagent and contained glucose and mannose, which together constituted 18.8% of the total antigen mass.	Mannose	93-100	SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)	Mus musculus	4-8
3720670-2	1986	Both drugs disrupted the processing of asparagine-linked oligosaccharides such that the secreted hCG forms contained mostly high mannose rather than complex oligosaccharide chains.	Mannose	129-136	chorionic gonadotropin subunit beta 5	Homo sapiens	97-100
3788408-2	1986	The pure alpha 1 acid glycoprotein (AGP) preparation from streptozotocin diabetic rat sera showed diminished sialic acid content and lower ratios of galactose to mannose and galactose to fucose.	Mannose	162-169	orosomucoid 1	Rattus norvegicus	9-34
3788408-2	1986	The pure alpha 1 acid glycoprotein (AGP) preparation from streptozotocin diabetic rat sera showed diminished sialic acid content and lower ratios of galactose to mannose and galactose to fucose.	Mannose	162-169	orosomucoid 1	Rattus norvegicus	36-39
3720670-4	1986	Both FCCP and methylamine also inhibited the incorporation of [35S] methionine and [3H]mannose into hCG subunits.	Mannose	87-94	chorionic gonadotropin subunit beta 5	Homo sapiens	100-103
3013314-4	1986	Treatment with isoproterenol or dibutyryl cAMP for 2 h affected glycosylation of immunoadsorbable lipoprotein lipase, so that the ratio of [3H]galactose to [14C]mannose in the heparin-releasable enzyme increased from 3.8 (control) to 13.0 (isoproterenol-treated).	Mannose	161-168	lipoprotein lipase	Rattus norvegicus	98-116
2424841-10	1986	gp55 is a glycoprotein containing a complex carbohydrate moiety with fucose, mannose, galactose, and glucose, either as terminal nonreducing units or substituted in positions indicated by methylation data.	Mannose	77-84	neuroplastin	Homo sapiens	0-4
2947571-7	1986	Thus, in their presence, alpha 1PI and alpha 1AGP with a mixture of both high-mannose and complex-type oligosaccharides were secreted.	Mannose	78-85	serpin family A member 1	Rattus norvegicus	25-34
2947571-7	1986	Thus, in their presence, alpha 1PI and alpha 1AGP with a mixture of both high-mannose and complex-type oligosaccharides were secreted.	Mannose	78-85	orosomucoid 1	Rattus norvegicus	39-49
3711662-3	1986	We have found remarkable similarities between the macrophage receptor(s) for promastigotes and a previously characterized eucaryotic receptor system, the mannose/fucose receptor (MFR), that mediates the binding of zymosan particles and mannose- or fucose-terminal glycoconjugates to macrophages.	Mannose	154-161	signal regulatory protein alpha	Homo sapiens	179-182
3711098-7	1986	The major carbohydrate residues of asialo-gpL115 are galactose and N-acetylgalactosamine in approximately equimolar amounts (25 and 22 residues/100 amino acids, respectively) plus severalfold lower amounts of N-acetylglucosamine, fucose, and mannose.	Mannose	242-249	sialophorin	Homo sapiens	42-48
3084653-5	1986	The p32 precursor was rapidly processed by addition of high-mannose-containing core N-linked sugars to intracytoplasmic precursor intermediates of 38,000 (p38) and 40,000 (p40) daltons, which undergo further processing to yield a mature surface receptor with heterogeneous apparent m.w.	Mannose	60-67	complement component 1, q subcomponent binding protein	Mus musculus	4-7
3086231-4	1986	Mannose-derived simple sugars inhibited the binding of SAP to macrophages and consequently prevented the enhanced SAP-dependent listericidal activity.	Mannose	0-7	amyloid P component, serum	Mus musculus	55-58
3086231-4	1986	Mannose-derived simple sugars inhibited the binding of SAP to macrophages and consequently prevented the enhanced SAP-dependent listericidal activity.	Mannose	0-7	amyloid P component, serum	Mus musculus	114-117
3529502-2	1986	Insulin release from the isolated islets was 26.2 microU/5 islets/hr in carbohydrate-free medium and increased by the addition of D-glucose or D-mannose.	Mannose	143-152	insulin	Homo sapiens	0-7
3099750-8	1986	The intracellular C1 Inh contains N-linked oligosaccharide units of the high-mannose type as demonstrated by endoglycosidase H-sensitivity.	Mannose	77-84	serpin family G member 1	Homo sapiens	18-24
3085511-5	1986	Moreover, granule AAT contains a reduced amount of N-acetylglucosamine and an increased amount of mannose, compared with plasma AAT.	Mannose	98-105	serpin family A member 1	Rattus norvegicus	18-21
3084653-5	1986	The p32 precursor was rapidly processed by addition of high-mannose-containing core N-linked sugars to intracytoplasmic precursor intermediates of 38,000 (p38) and 40,000 (p40) daltons, which undergo further processing to yield a mature surface receptor with heterogeneous apparent m.w.	Mannose	60-67	mitogen-activated protein kinase 14	Mus musculus	155-158
3084653-5	1986	The p32 precursor was rapidly processed by addition of high-mannose-containing core N-linked sugars to intracytoplasmic precursor intermediates of 38,000 (p38) and 40,000 (p40) daltons, which undergo further processing to yield a mature surface receptor with heterogeneous apparent m.w.	Mannose	60-67	interleukin 12b	Mus musculus	172-175
3010996-2	1986	We report that recombinant interferon (rIFN gamma) and IFN alpha/beta mediate distinct, antagonistic effects on expression of a lectin-like receptor for mannose and fucose (MFR) on mouse peritoneal macrophages (M phi).	Mannose	153-160	interferon gamma	Rattus norvegicus	39-49
2420791-12	1986	Structural analysis of these reaction products indicated that the purified soluble form of ER alpha-mannosidase shows little specificity for which mannose residues it removes from Man9GlcNAc.	Mannose	147-154	estrogen receptor 1	Rattus norvegicus	91-99
3711061-1	1986	Lysosomal acid alpha-mannosidase from porcine kidney was found to contain mannose (4.8%), galactose (0.9%), fucose (0.5%), N-acetylglucosamine (3.1%), and mannose 6-phosphate (0.1%).	Mannose	74-81	mannosidase alpha class 2B member 1	Homo sapiens	0-32
2420791-6	1986	Like the membrane-bound ER alpha-mannosidase, the soluble alpha-mannosidase can hydrolyze alpha-linked mannose from both p-nitrophenyl alpha-mannoside (Km = 0.14 mM) and high mannose oligosaccharides, is not inhibited by the mannose analogues swainsonine and 1-deoxymannojirimycin, is stabilized by MnCl2 or CoCl2, and does not bind to concanavalin A-Sepharose.	Mannose	103-110	estrogen receptor 1	Rattus norvegicus	24-32
3010996-2	1986	We report that recombinant interferon (rIFN gamma) and IFN alpha/beta mediate distinct, antagonistic effects on expression of a lectin-like receptor for mannose and fucose (MFR) on mouse peritoneal macrophages (M phi).	Mannose	153-160	interferon alpha	Mus musculus	55-64
2469930-0	1986	The role of fimbriae of uropathogenic Escherichia coli as carriers of the adhesin involved in mannose-resistant hemagglutination.	Mannose	94-101	adhesin	Escherichia coli	74-81
3457370-2	1986	Ovalbumin synthesized in mouse L-353 cells is glycosylated, as judged by incorporation of [3H]mannose and susceptibility to endo-beta-N-acetylglucosaminidases.	Mannose	94-101	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	0-9
3457370-5	1986	Approximately 50% of the [3H]mannose incorporated into ovalbumin secreted by L cells is found in such hybrid structures.	Mannose	29-36	ovalbumin (SERPINB14)	Gallus gallus	55-64
3964668-8	1986	The carbohydrate portion of the lectin contains mannose; no hexosamines could be detected.	Mannose	48-55	LOW QUALITY PROTEIN: lectin	Glycine max	32-38
3081567-4	1986	The duodenal alkaline phosphatase had a low content of this fraction, although the content of this fraction obtained from duodenal explants was increased markedly when explants were cultured with swainsonine, which is an inhibitor of alpha-mannosidase II, and this leads to the accumulation of high-mannose-type and hybrid-type sugar chains in the pathway of sugar chain processing.	Mannose	299-306	mannosidase, alpha, class 2A, member 1	Rattus norvegicus	234-254
3007151-8	1986	Results from digestion with endoglycosidase H, incubation with tunicamycin and metabolic labelling with [3H]mannose indicated that myeloperoxidase contained high mannose oligosaccharide side chains.	Mannose	108-115	myeloperoxidase	Homo sapiens	131-146
3837694-8	1985	Human FIF activity was significantly reduced in the presence of several sugars including alpha-methyl-D-mannoside, L-xylose, N-acetyl-D-glucosamine, D-mannose, L-rhamnose but not L-fucose.	Mannose	149-158	apoptosis inhibitor 5	Homo sapiens	6-9
4052441-7	1985	The immunoadsorbable lipoprotein lipase in the intracellular compartment has a [14C]mannose to [3H]galactose ratio of 0.15 and this ratio increased 6-fold in monensin-treated cells.	Mannose	84-91	lipoprotein lipase	Rattus norvegicus	21-39
2866240-1	1985	The "high-mannose" glycosylated forms of aminopeptidase N (EC 3.4.11.2), maltase-glucoamylase (EC 3.2.1.20), and sucrase-isomaltase (EC 3.2.1.48, EC 3.2.1.10) have been purified.	Mannose	10-17	maltase-glucoamylase	Homo sapiens	73-93
2866240-2	1985	The high-mannose glycosylated form of sucrase-isomaltase was found to have a lower specific activity than the complex glycosylated form, whereas no difference was observed for the two other enzymes.	Mannose	9-16	sucrase-isomaltase	Homo sapiens	38-56
2866240-3	1985	The change in glycosylation from high-mannose to complex form thus seems to be of importance for the enzymatic activity of sucrase-isomaltase either by direct structural involvement or by a general stabilization effect on the protein conformation.	Mannose	38-45	sucrase-isomaltase	Homo sapiens	123-141
3003043-2	1985	The serum mannan-binding protein (MBP) is a lectin specific for mannose and N-acetylglucosamine.	Mannose	64-71	mannose binding lectin 2	Bos taurus	10-32
3003043-2	1985	The serum mannan-binding protein (MBP) is a lectin specific for mannose and N-acetylglucosamine.	Mannose	64-71	mannose binding lectin 2	Bos taurus	34-37
3003043-7	1985	Both bound with high affinity (Kd = 10(-8) M) to glycoproteins terminated with mannose and/or N-acetylglucosamine residues in the presence of calcium, although conglutinin preferred N-acetylglucosamine rather than mannose.	Mannose	214-221	conglutinin	Bos taurus	160-171
2864287-3	1985	The conversion from transient (high mannose glycosylated) to mature (complex glycosylated) form was 1.7-times slower for sucrase-isomaltase than for aminopeptidase N, indicating a slower rate of migration from the rough endoplasmic reticulum to the Golgi complex.	Mannose	36-43	sucrase-isomaltase	Sus scrofa	121-139
2864287-3	1985	The conversion from transient (high mannose glycosylated) to mature (complex glycosylated) form was 1.7-times slower for sucrase-isomaltase than for aminopeptidase N, indicating a slower rate of migration from the rough endoplasmic reticulum to the Golgi complex.	Mannose	36-43	alanyl aminopeptidase, membrane	Sus scrofa	149-165
4043085-9	1985	Apolipoprotein-B in low-density lipoproteins was calculated to contain five high-mannose chains in total.	Mannose	81-88	apolipoprotein B	Homo sapiens	0-16
3906028-3	1985	Glucokinase proved to be a glucomannokinase with Km values of 0.04 mM for both glucose and mannose.	Mannose	91-98	glucokinase	Saccharomyces cerevisiae S288C	0-11
4074717-3	1985	In primary cultures of thyrotropic tumor cells incubated for 60 min with [3H]mannose, primarily Man9GlcNAc and Man8GlcNAc were found on TSH + alpha subunits, whereas Glc1Man9GlcNAc and Man9GlcNAc were prominent on free beta subunits.	Mannose	77-84	glycoprotein hormones, alpha subunit	Mus musculus	136-147
4074717-4	1985	After preincubation of cells for 16 h in the presence or absence of glucose followed by a 60-min pulse of [3H]mannose, there was an 8-fold increase in labeled TSH + alpha but only a minimal change in free beta or total proteins.	Mannose	110-117	glycoprotein hormones, alpha subunit	Mus musculus	159-170
3899013-1	1985	Homogenates of insulin-producing tumoral cells catalyzed the phosphorylation of glucose, mannose, and fructose.	Mannose	89-96	insulin	Homo sapiens	15-22
3161507-5	1985	The binding of IgM and IgG coated red blood cells to liver macrophages could not be blocked by potent inhibitors for mannose- and galactose-specific macrophage lectins such as mannan, D-mannose-bovine serum albumin, N-acetyl-D-galactosamine, D-galactose-bovine serum albumin, or asialofetuin.	Mannose	184-193	immunoglobulin heavy chain 6	Rattus norvegicus	15-18
4026327-1	1985	Two binding proteins which recognize and bind mannose and N-acetylglucosamine (mannan-binding proteins, MBP) have been isolated from chicken liver to near homogeneity mainly by affinity chromatography on a column of Sepharose 4B-mannan.	Mannose	46-53	myelin basic protein	Gallus gallus	104-107
4052025-7	1985	The carbohydrate of eosinophil peroxidase seemed associated exclusively with the large subunit and comprised mannose (4.5%, w/w) and N-acetylglucosamine (0.8%, w/w).	Mannose	109-116	eosinophil peroxidase	Homo sapiens	20-41
4031068-3	1985	From 6 to 22 h, there was a progressive increase in the incorporation of [3H]mannose into the insulin proreceptor (190,000 mol wt) and the mature subunits (210,000, 135,000, and 95,000 mol wt).	Mannose	77-84	insulin	Homo sapiens	94-101
3927903-5	1985	Pulse-labelling of cultured medullary thyroid carcinoma cells with [3H]-mannose indicate that detectable quantities of carbohydrate-containing forms of calcitonin are produced in these cells.	Mannose	72-79	calcitonin related polypeptide alpha	Homo sapiens	152-162
3890955-0	1985	Anomeric specificity of mannose phosphorylation by hexokinase.	Mannose	24-31	hexokinase 1	Homo sapiens	51-61
3890955-1	1985	In rat parotid or pancreatic islet homogenates incubated at 7 degrees C, hexokinase displayed a greater affinity for but a lower maximal velocity with the alpha-anomer, as distinct from beta-anomer, of D-mannose.	Mannose	202-211	hexokinase	Saccharomyces cerevisiae S288C	73-83
3890955-2	1985	The anomeric specificity of mammalian hexokinase was similar in the case of D-mannose and D-glucose, but represented a mirror image of that of yeast hexokinase.	Mannose	76-85	hexokinase 1	Homo sapiens	38-48
3160588-0	1985	Secretion of high-mannose-type alpha 1-proteinase inhibitor and alpha 1-acid glycoprotein by primary cultures of rat hepatocytes in the presence of the mannosidase I inhibitor 1-deoxymannojirimycin.	Mannose	18-25	serpin family A member 1	Rattus norvegicus	31-59
3873494-5	1985	Ii-c is resistant to deglycosylation by Endo H, which is specific for high-mannose N-linkages, but can be digested with Endo F, a glycosidase capable of cleaving both complex and high-mannose N-linked oligosaccharides.	Mannose	75-82	myosin, heavy polypeptide 14	Mus musculus	0-4
3925457-6	1985	This protein presumably is the high-mannose precursor of sucrase-isomaltase.	Mannose	36-43	sucrase-isomaltase	Homo sapiens	57-75
3888115-8	1985	Cathepsin D heavy chain is heterogeneous, having three major species with pI"s of 5.7, 5.3, and 4.9; all forms are glycosylated with high mannose-type chains [approximate size: Man5(GlcNAc)2] and are partially phosphorylated.	Mannose	138-145	cathepsin D	Homo sapiens	0-11
4005322-7	1985	Cathepsin D contains 6.4% carbohydrates consisting of mannose, galactose, fucose and glucosamine at a ratio of 3:9:2:2.	Mannose	54-61	cathepsin D	Oryctolagus cuniculus	0-11
3971914-4	1985	Both forms are converted to mature PRL by digestion with endoglycosidase H and, thus, appear to contain only asparagine-linked, high mannose-type carbohydrate moieties.	Mannose	133-140	prolactin	Bos taurus	35-38
3884512-3	1985	The addition of exogenous plasma fibronectin to the cell lines or oral epithelial cells enhanced binding of S. pyogenes but suppressed binding of mannose-sensitive E. coli.	Mannose	146-153	fibronectin 1	Homo sapiens	33-44
3884512-4	1985	These findings are consistent with the notion that exogenously acquired fibronectin on the surface of host cells modulates bacterial adherence by providing attachment sites for certain pathogens, such as S. pyogenes, and by blocking receptors for others, such as mannose-sensitive E. coli.	Mannose	263-270	fibronectin 1	Homo sapiens	72-83
3972840-2	1985	Most of the uteroferrin isolated from either uterine secretions or allantoic fluid has endoglycosidase H-sensitive carbohydrate chains with either five or six mannose residues.	Mannose	159-166	acid phosphatase 5, tartrate resistant	Sus scrofa	12-23
2859851-5	1985	The results show that both types of cells possess Thy-1 molecules with three N-linked carbohydrate chains, of which one is of "high-mannose" type and the other two of triantennary and biantennary "complex" type.	Mannose	132-139	thymus cell antigen 1, theta	Mus musculus	50-55
3893560-1	1985	Pregnant rabbit mammary gland explants cultured with insulin, prolactin and cortisol synthesize and secrete transferrin radiolabelled with [3H]leucine or [3H]mannose.	Mannose	158-165	prolactin	Oryctolagus cuniculus	62-71
3919149-7	1985	The glycoproteins of purified RS virus (GP1, VGP48 and GP26) contain mannose, galactose and fucose as well as glucosamine, but the quantity of mannose in GP1 is low when compared to that of the other three sugars.	Mannose	69-76	GTP binding protein 1	Homo sapiens	40-43
3919149-7	1985	The glycoproteins of purified RS virus (GP1, VGP48 and GP26) contain mannose, galactose and fucose as well as glucosamine, but the quantity of mannose in GP1 is low when compared to that of the other three sugars.	Mannose	143-150	GTP binding protein 1	Homo sapiens	154-157
2579069-6	1985	When alpha 1-antitrypsin was immunoprecipitated from the cell lysates, sodium dodecyl sulfate-polyacrylamide gel electrophoresis fluorographic analysis demonstrated that the conversion of the high-mannose precursor to the hybrid form in swainsonine-treated cells occurred more rapidly (by about 10 min) than the conversion to the complex form in control cells.	Mannose	197-204	serpin family A member 1	Homo sapiens	5-24
3882690-3	1985	The latter enzyme is very specific and removes a single mannose residue from Man9GlcNAc, whereas the alpha-mannosidase activity of Fraction I removes several mannose residues from Man9GlcNAc oligosaccharide.	Mannose	158-165	alpha-mannosidase	Saccharomyces cerevisiae S288C	101-118
3882690-5	1985	The mannose analog of 1-deoxynojirimycin (50-500 microM), dideoxy-1,5-imino-D-mannitol, inhibits the oligosaccharide alpha-mannosidase activities of Fractions I and II to about the same extent, but has no effect on the nonspecific alpha-mannosidase which acts on p-nitrophenyl-alpha-D-mannopyranoside.	Mannose	4-11	alpha-mannosidase	Saccharomyces cerevisiae S288C	117-134
3882690-5	1985	The mannose analog of 1-deoxynojirimycin (50-500 microM), dideoxy-1,5-imino-D-mannitol, inhibits the oligosaccharide alpha-mannosidase activities of Fractions I and II to about the same extent, but has no effect on the nonspecific alpha-mannosidase which acts on p-nitrophenyl-alpha-D-mannopyranoside.	Mannose	4-11	alpha-mannosidase	Saccharomyces cerevisiae S288C	231-248
2856927-4	1985	During chase, this band converted to a molecular ratio (Mr) = 25,000 polypeptide, probably derived from the latter by trimming of glucose or mannose residues from the three high-mannose glycan units of Thy-1.	Mannose	178-185	thymus cell antigen 1, theta	Mus musculus	202-207
3917691-0	1985	Phosphorylated high mannose-type and hybrid-type oligosaccharide chains of human thyroglobulin isolated from malignant thyroid tissue.	Mannose	20-27	thyroglobulin	Homo sapiens	81-94
3917691-2	1985	It was revealed that sialylated hybrid-type oligosaccharides were present in thyroglobulin from normal thyroid tissue, whereas, in the case of thyroglobulin from malignant thyroid tissue, phosphorylated high-mannose type and hybrid-type oligosaccharides each containing one phosphate group in a diester linkage were present instead of sialylated oligosaccharides.	Mannose	208-215	thyroglobulin	Homo sapiens	143-156
3881127-1	1985	D-Mannose derivatives have been synthesised which are crosslinked through their C-4 hydroxyls to propyl-2-amine.	Mannose	0-9	complement C4A (Rodgers blood group)	Homo sapiens	80-83
2942205-3	1985	The sst1 phenotype was first observed in a pleiotropic fdp mutant which does not grow on mannose, sucrose, glucose or fructose, and in its partial spontaneous revertant (Q6R2) which acquired the capacity to grow on glucose but retained the mutant phenotype with respect to fructose.	Mannose	89-96	aspartyl protease BAR1	Saccharomyces cerevisiae S288C	4-8
4053569-2	1985	The hexose (galactose + mannose) content of Macaca transferrin is 4.7 mole per mole of protein.	Mannose	24-31	INHCAP	Macaca fascicularis	51-62
3918878-4	1985	We synthesized a probe by covalently linking D-mannose to bovine serum albumin (BSA).	Mannose	45-54	albumin	Homo sapiens	65-78
2856916-1	1985	Earlier studies have shown that the majority of Escherichia coli isolates from urinary tract infections which possess a D-mannose-resistant adhesin contain gene sequences homologous to the pap pilus gene sequences encoded on the recombinant plasmid pRHU845.	Mannose	120-129	putative antirestriction protein	Escherichia coli	189-192
3937748-3	1985	In vitro uptake of beta-galactosidase in hepatocytes and nonparenchymal liver cells was saturable, Ca2+-dependent and it could be partly inhibited by mannose or alpha-methyl-mannoside.	Mannose	150-157	galactosidase, beta 1	Rattus norvegicus	19-37
3968538-5	1985	[3H]Mannose-labelled E1, E2, GP59(E1) and GP43(E2) were digested with Pronase and the glycopeptides separated by gel filtration.	Mannose	4-11	small nucleolar RNA, H/ACA box 73A	Homo sapiens	29-37
3968538-5	1985	[3H]Mannose-labelled E1, E2, GP59(E1) and GP43(E2) were digested with Pronase and the glycopeptides separated by gel filtration.	Mannose	4-11	cystatin 12, pseudogene	Homo sapiens	42-50
6210286-17	1984	The initial trimming of glucosyl and mannosyl units from the high-mannose oligosaccharides of the hCG precursors occurred more rapidly for free alpha and CG-alpha than for free beta and CG-beta.	Mannose	66-73	chorionic gonadotropin subunit beta 5	Homo sapiens	98-101
6210286-17	1984	The initial trimming of glucosyl and mannosyl units from the high-mannose oligosaccharides of the hCG precursors occurred more rapidly for free alpha and CG-alpha than for free beta and CG-beta.	Mannose	66-73	chromogranin A	Homo sapiens	154-162
6210286-17	1984	The initial trimming of glucosyl and mannosyl units from the high-mannose oligosaccharides of the hCG precursors occurred more rapidly for free alpha and CG-alpha than for free beta and CG-beta.	Mannose	66-73	chorionic gonadotropin subunit beta 3	Homo sapiens	186-193
6209184-8	1984	The lack of effect of galactose on DBH levels, together with the induced increase of DBH by alpha-methyl-D-mannoside and, to a lesser extent, by inulin, suggest an important rate for the mannose/glucose/N-acetyl glucosamine/fructose receptor in the catabolic clearance of DBH from plasma and explain the abnormal values seen for DBH in diabetes mellitus.	Mannose	187-194	dopamine beta-hydroxylase	Rattus norvegicus	85-88
6209184-8	1984	The lack of effect of galactose on DBH levels, together with the induced increase of DBH by alpha-methyl-D-mannoside and, to a lesser extent, by inulin, suggest an important rate for the mannose/glucose/N-acetyl glucosamine/fructose receptor in the catabolic clearance of DBH from plasma and explain the abnormal values seen for DBH in diabetes mellitus.	Mannose	187-194	dopamine beta-hydroxylase	Rattus norvegicus	85-88
6209184-8	1984	The lack of effect of galactose on DBH levels, together with the induced increase of DBH by alpha-methyl-D-mannoside and, to a lesser extent, by inulin, suggest an important rate for the mannose/glucose/N-acetyl glucosamine/fructose receptor in the catabolic clearance of DBH from plasma and explain the abnormal values seen for DBH in diabetes mellitus.	Mannose	187-194	dopamine beta-hydroxylase	Rattus norvegicus	85-88
6489350-2	1984	Hexokinase D ("glucokinase") displays positive cooperativity with mannose with the same h values (1.5-1.6) as with glucose but with higher K0.5 values (8 mM at pH 8.0 and 12 mM at pH 7.5).	Mannose	66-73	glucokinase	Homo sapiens	15-27
6092383-1	1984	Thyroxine-binding globulin (TBG) synthesis by human hepatoma (Hep G2) cells was demonstrated by pulse labeling with [35S]methionine or [3H]mannose and subsequent immunoprecipitation in the medium or cell lysate.	Mannose	139-146	serpin family A member 7	Homo sapiens	0-26
6092383-1	1984	Thyroxine-binding globulin (TBG) synthesis by human hepatoma (Hep G2) cells was demonstrated by pulse labeling with [35S]methionine or [3H]mannose and subsequent immunoprecipitation in the medium or cell lysate.	Mannose	139-146	serpin family A member 7	Homo sapiens	28-31
6240981-5	1984	The inhibition of glucokinase activity by alloxan was protected by the simultaneous presence of 15 mM hexose such as D-glucose, 3-O-methylglucose, or D-mannose.	Mannose	150-159	glucokinase	Rattus norvegicus	18-29
6481160-2	1984	The CR-7 mutant, which has a decreased ability to incorporate mannose into oligolipid and membrane glycoprotein and an increased membrane fucose, was more sensitive to natural killer (NK) cell lysis than the parental wild type (CHO-WT).	Mannose	62-69	teratocarcinoma-derived growth factor 1 pseudogene 7	Homo sapiens	4-8
6208685-14	1984	After treatment, the electrophoretic mobility of gA2, gA3, and gA6 increased significantly suggesting that these forms contain high-mannose chains cleaved by the enzyme.	Mannose	132-139	electron transfer flavoprotein subunit alpha	Homo sapiens	49-52
6208685-14	1984	After treatment, the electrophoretic mobility of gA2, gA3, and gA6 increased significantly suggesting that these forms contain high-mannose chains cleaved by the enzyme.	Mannose	132-139	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	54-57
6479236-1	1984	Monensin impairs oligosaccharide processing in fibronectin primarily by inhibiting the conversion of oligosaccharides from the high mannose type to the complex type.	Mannose	132-139	fibronectin 1	Homo sapiens	47-58
6088806-3	1984	All pronase-digested glycopeptides of pgC were susceptible to endo-beta-N-acetylglucosaminidase H treatment; thus they have a high-mannose structure.	Mannose	131-138	progastricsin	Homo sapiens	38-41
6746670-8	1984	The carbohydrate of cathepsin B consisted of a single residue of glucosamine and trace mannose.	Mannose	87-94	cathepsin B	Homo sapiens	20-31
6478459-4	1984	The 3,6-dideoxyhexose to D-mannose linkage was shown to possess a steep energy surface with a minimum, which results in good exposure of the dideoxyhexose O-2 and O-4 atoms.	Mannose	25-34	immunoglobulin kappa variable 1D-39	Homo sapiens	155-166
6742851-1	1984	The subcellular distribution of the mannan-binding protein from rat liver, a lectin specific for mannose and N-acetylglucosamine, was studied.	Mannose	97-104	mannose binding lectin 1	Rattus norvegicus	36-58
6725252-3	1984	As described in this report, the latter lectin binds glycopeptides that contain either the repeating N-acetyllactosamine sequence or an outer mannose residue substituted at C-2 and C-6 by N-acetyllactosamine.	Mannose	142-149	complement component 2 (within H-2S)	Mus musculus	173-176
6725252-3	1984	As described in this report, the latter lectin binds glycopeptides that contain either the repeating N-acetyllactosamine sequence or an outer mannose residue substituted at C-2 and C-6 by N-acetyllactosamine.	Mannose	142-149	complement component 6	Mus musculus	181-184
3904632-8	1985	Sensitivity of phosphorylated oligosaccharide chains from precursor, mature and small polypeptides to endo-beta-hexosaminidase H-catalyzed cleavage suggests the presence of high-mannose phosphorylated oligosaccharide chains similar to those present on many other lysosomal enzymes.	Mannose	178-185	O-GlcNAcase	Homo sapiens	107-126
4052441-9	1985	The present results indicate that: the presence of asparagine-linked oligosaccharide (formation of which is inhibited by tunicamycin) is mandatory for the expression of lipoprotein lipase activity; lipoprotein lipase is active also in a high mannose form; and terminal glycosylation and oligosaccharide processing, which is inhibited by monensin, may be important for the appearance of heparin-releasable lipoprotein lipase and secretion of lipoprotein lipase into the medium.	Mannose	242-249	lipoprotein lipase	Rattus norvegicus	169-187
4052441-9	1985	The present results indicate that: the presence of asparagine-linked oligosaccharide (formation of which is inhibited by tunicamycin) is mandatory for the expression of lipoprotein lipase activity; lipoprotein lipase is active also in a high mannose form; and terminal glycosylation and oligosaccharide processing, which is inhibited by monensin, may be important for the appearance of heparin-releasable lipoprotein lipase and secretion of lipoprotein lipase into the medium.	Mannose	242-249	lipoprotein lipase	Rattus norvegicus	198-216
4052441-9	1985	The present results indicate that: the presence of asparagine-linked oligosaccharide (formation of which is inhibited by tunicamycin) is mandatory for the expression of lipoprotein lipase activity; lipoprotein lipase is active also in a high mannose form; and terminal glycosylation and oligosaccharide processing, which is inhibited by monensin, may be important for the appearance of heparin-releasable lipoprotein lipase and secretion of lipoprotein lipase into the medium.	Mannose	242-249	lipoprotein lipase	Rattus norvegicus	198-216
4052441-9	1985	The present results indicate that: the presence of asparagine-linked oligosaccharide (formation of which is inhibited by tunicamycin) is mandatory for the expression of lipoprotein lipase activity; lipoprotein lipase is active also in a high mannose form; and terminal glycosylation and oligosaccharide processing, which is inhibited by monensin, may be important for the appearance of heparin-releasable lipoprotein lipase and secretion of lipoprotein lipase into the medium.	Mannose	242-249	lipoprotein lipase	Rattus norvegicus	198-216
6587337-5	1984	On uteroferrin, however, the majority of the phosphate is in single diester linkages between the mannose and a covering N-acetylglucosamine.	Mannose	97-104	acid phosphatase 5, tartrate resistant	Sus scrofa	3-14
6230110-3	1984	The N-acetylglucosaminyltransferases I and II (enzymes which attach N-acetylglucosamine to either the 3" or 6" core mannose, respectively) were assayed with structurally-defined glycopeptides as specific acceptors and galactosyltransferase was assayed with asialo, agalactosylfetuin (galactose is attached to exposed N-acetylglucosamine termini).	Mannose	116-123	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	4-45
6715343-0	1984	Retinoic acid alters the proportion of high mannose to complex type oligosaccharides on fibronectin secreted by cultured chondrocytes.	Mannose	44-51	fibronectin 1	Homo sapiens	88-99
6325341-11	1984	The LDCL responses which were induced by mixtures of PARG and concanavalin A were also strongly inhibited by mannose, alpha-methyl mannoside, and poly-L-glutamic acid.	Mannose	109-116	poly(ADP-ribose) glycohydrolase	Homo sapiens	53-57
6422851-1	1984	Sequential digestion of human thrombin and antithrombin with neuraminidase, beta-galactosidase, beta-N-acetylglucosaminidase, and endo-beta-N-acetylglucosaminidase D resulted in the successive removal of sialic acid, galactose, N-acetylglucosamine, and mannose and more N-acetylglucosamine residues.	Mannose	253-260	O-GlcNAcase	Homo sapiens	96-124
6422851-1	1984	Sequential digestion of human thrombin and antithrombin with neuraminidase, beta-galactosidase, beta-N-acetylglucosaminidase, and endo-beta-N-acetylglucosaminidase D resulted in the successive removal of sialic acid, galactose, N-acetylglucosamine, and mannose and more N-acetylglucosamine residues.	Mannose	253-260	O-GlcNAcase	Homo sapiens	135-163
6422853-1	1984	Cathepsin D from porcine spleen contained mannose (3.3%), glucosamine (1.4%), and mannose 6-phosphate (0.08%).	Mannose	42-49	cathepsin D	Homo sapiens	0-11
6422853-11	1984	Cathepsin D was bound to a mannose- and N-acetylglucosamine-specific lectin (mannan-binding protein) isolated from rabbit liver with the Ki value of 5.4 X 10(-6) M.	Mannose	27-34	cathepsin D	Oryctolagus cuniculus	0-11
6692539-3	1984	D-Mannose concentration is calculated from the increase in NADH formation after mannosephosphate isomerase (EC 5.3.1.8) is added.	Mannose	0-9	mannose phosphate isomerase	Homo sapiens	80-106
24253332-4	1984	On the other hand, the synthesis of exocellular polysaccharides composed of glucose, galactose, mannose and arabinose etc., was stimulated and a clear increase of the Man/Ara ratio was observed in the presence of GA3.	Mannose	96-103	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	213-216
6320537-5	1984	The aberrant cleavage products, gp75mon and gp30mon, produced in the presence of monensin, carry oligosaccharides where only 1-3 mannose residues have been removed in comparison to the precursor gPr92env (this latter carries predominantly Man9(GlcNAc)2).	Mannose	129-136	tyrosinase related protein 1	Homo sapiens	32-36
6363129-5	1984	Treatment of aminopeptidase N and sucrase-isomaltase with endo F reduced the size of the high mannose forms approximately to those seen in the presence of tunicamycin.	Mannose	94-101	alanyl aminopeptidase, membrane	Sus scrofa	13-29
6363129-5	1984	Treatment of aminopeptidase N and sucrase-isomaltase with endo F reduced the size of the high mannose forms approximately to those seen in the presence of tunicamycin.	Mannose	94-101	sucrase-isomaltase	Sus scrofa	34-52
6368538-1	1984	The yeast Saccharomyces cerevisiae temperature-sensitive lethal mutant alg1-1, has been previously shown to lack the activity necessary for the addition of the first mannose residue in the synthesis of lipid-linked precursor oligosaccharide.	Mannose	166-173	alpha-1,2-mannosyltransferase ALG11	Saccharomyces cerevisiae S288C	71-77
6434908-7	1984	However, the rates of F II of MAF and IFN activities increased proportionally when the sample was applied on a column of higher capacity, suggesting that the molecular structure of the mannose-containing glycosyl moiety of the two molecules may also be similar.	Mannose	185-192	avian musculoaponeurotic fibrosarcoma oncogene homolog	Mus musculus	30-33
6417140-8	1983	However, monensin-treated cells secreted hCG subunits that contained endo H-sensitive oligosaccharides of the high mannose (mostly Man5GlcNAc2) and hybrid types rather than the endo H-resistant complex chains synthesized by control cells.	Mannose	115-122	chorionic gonadotropin subunit beta 5	Homo sapiens	41-44
6643476-0	1983	The binding and processing of mannose-bovine serum albumin derivatives by rabbit alveolar macrophages.	Mannose	30-37	albumin	Oryctolagus cuniculus	45-58
6317500-0	1983	Mannose phosphorylation by glucokinase from liver and transplantable insulinoma.	Mannose	0-7	glucokinase	Rattus norvegicus	27-38
6317500-3	1983	Phosphorylation of alpha,beta-D-mannose by glucokinase occurred with cooperative rate dependence on mannose concentration (nH: 1.50).	Mannose	32-39	glucokinase	Rattus norvegicus	43-54
6317500-8	1983	Islet glucokinase has previously been shown to be chromatographically and kinetically identical to glucokinase from insulinoma and liver; therefore, evidence that glucokinase from these two tissues phosphorylates mannose with cooperative rate dependence and differentiates mannose anomers supports the glucokinase-glucose sensor hypothesis.	Mannose	213-220	glucokinase	Rattus norvegicus	6-17
6317500-8	1983	Islet glucokinase has previously been shown to be chromatographically and kinetically identical to glucokinase from insulinoma and liver; therefore, evidence that glucokinase from these two tissues phosphorylates mannose with cooperative rate dependence and differentiates mannose anomers supports the glucokinase-glucose sensor hypothesis.	Mannose	213-220	glucokinase	Rattus norvegicus	99-110
6317500-8	1983	Islet glucokinase has previously been shown to be chromatographically and kinetically identical to glucokinase from insulinoma and liver; therefore, evidence that glucokinase from these two tissues phosphorylates mannose with cooperative rate dependence and differentiates mannose anomers supports the glucokinase-glucose sensor hypothesis.	Mannose	213-220	glucokinase	Rattus norvegicus	99-110
6317500-8	1983	Islet glucokinase has previously been shown to be chromatographically and kinetically identical to glucokinase from insulinoma and liver; therefore, evidence that glucokinase from these two tissues phosphorylates mannose with cooperative rate dependence and differentiates mannose anomers supports the glucokinase-glucose sensor hypothesis.	Mannose	213-220	glucokinase	Rattus norvegicus	99-110
6317500-8	1983	Islet glucokinase has previously been shown to be chromatographically and kinetically identical to glucokinase from insulinoma and liver; therefore, evidence that glucokinase from these two tissues phosphorylates mannose with cooperative rate dependence and differentiates mannose anomers supports the glucokinase-glucose sensor hypothesis.	Mannose	273-280	glucokinase	Rattus norvegicus	6-17
6361221-3	1983	B1 and B3 are derived from two precursors, P1 (Mr approximately 210,000) and P3 (Mr approximately 185,000) which are nonsialylated, mannose-rich proteins not exposed on the cell surface.	Mannose	132-139	UDP glucuronosyltransferase family 1 member A1	Rattus norvegicus	0-9
6416296-10	1983	Though fructose and mannose also showed significant inhibition of beta-glucuronidase at 10-100 mM, glucose did not show any effect.	Mannose	20-27	glucuronidase beta	Homo sapiens	66-84
6139091-1	1983	A comparative study by gel-permeation chromatographic analysis of oligosaccharides released from the heavy and the light subunits of rat kidney gamma-glutamyltranspeptidase has revealed that high-mannose-type sugar chains are found only in the heavy subunit, and the nonsialylated and nonfucosylated biantennary complex-type sugar chains are included only in the light subunit.	Mannose	196-203	gamma-glutamyltransferase 1	Rattus norvegicus	144-172
6226656-3	1983	Hepatocytes treated with 5 mM 1-deoxynojirimycin accumulated alpha 1-proteinase inhibitor as a 51,000 Mr glycoprotein with carbohydrate side chains of the high mannose type, containing glucose as measured by their sensitivity against alpha-glucosidase, the largest species being Glc3Man9GlcNAc.	Mannose	160-167	serpin family A member 1	Rattus norvegicus	61-89
6385980-2	1983	This result may explain our previous findings of the alpha-anomeric preference in glucose- and mannose-stimulated insulin release, and therefore suggests to support the hypothesis that glucokinase in islets functions as a crucial hexose sensing enzyme for insulin release induced by glucose and mannose.	Mannose	95-102	glucokinase	Rattus norvegicus	185-196
6385980-2	1983	This result may explain our previous findings of the alpha-anomeric preference in glucose- and mannose-stimulated insulin release, and therefore suggests to support the hypothesis that glucokinase in islets functions as a crucial hexose sensing enzyme for insulin release induced by glucose and mannose.	Mannose	295-302	glucokinase	Rattus norvegicus	185-196
6626154-10	1983	The formation of the "metachromatic complex" between Ret-P and Mn(II) or Co(II) inhibited the synthesis of retinyl phosphate mannose (Ret-P-Man) from exogenous and endogenous Ret-P and guanosine diphosphate [14C]mannose when bovine serum albumin was added after the metal ion.	Mannose	125-132	ret proto-oncogene	Rattus norvegicus	53-56
6626154-10	1983	The formation of the "metachromatic complex" between Ret-P and Mn(II) or Co(II) inhibited the synthesis of retinyl phosphate mannose (Ret-P-Man) from exogenous and endogenous Ret-P and guanosine diphosphate [14C]mannose when bovine serum albumin was added after the metal ion.	Mannose	125-132	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	73-79
6626154-10	1983	The formation of the "metachromatic complex" between Ret-P and Mn(II) or Co(II) inhibited the synthesis of retinyl phosphate mannose (Ret-P-Man) from exogenous and endogenous Ret-P and guanosine diphosphate [14C]mannose when bovine serum albumin was added after the metal ion.	Mannose	125-132	ret proto-oncogene	Rattus norvegicus	134-137
6626154-10	1983	The formation of the "metachromatic complex" between Ret-P and Mn(II) or Co(II) inhibited the synthesis of retinyl phosphate mannose (Ret-P-Man) from exogenous and endogenous Ret-P and guanosine diphosphate [14C]mannose when bovine serum albumin was added after the metal ion.	Mannose	125-132	ret proto-oncogene	Rattus norvegicus	134-137
6411700-12	1983	In conclusion, the Mr = 190,000 component appears to represent the high mannose precursor form of the insulin receptor that undergoes carbohydrate processing and proteolytic cleavage to generate the two major subunits.	Mannose	72-79	insulin receptor	Homo sapiens	102-118
6603275-3	1983	Mouse NK activity against YAC-1 target cells was reduced consistently in the presence of D-mannose and NAcGlc only.	Mannose	89-98	ADP-ribosyltransferase 1	Mus musculus	26-31
6307147-1	1983	An investigation of the structure and biosynthesis of alpha-galactosidase A (alpha-D-galactoside glycohydrolase, EC 3.2.1.22) and its N-linked oligosaccharide chains was undertaken by metabolic labeling of Chang liver cells with [2-3H]mannose, immunoprecipitation of the activity, and examination of the resulting immunoprecipitates.	Mannose	235-242	galactosidase alpha	Homo sapiens	54-75
6225773-4	1983	After removal of the peripheral N-acetylglucosamine and galactose residues by exhaustive glycosidase digestion, the residual glycopeptide (GP-A) was found to contain 0.6 mol of fucose, 3 mol of mannose, and 2 mol of N-acetylglucosamine per mol.	Mannose	194-201	glycophorin-A	Bos taurus	139-143
6867011-5	1983	Mannose (C-2 epimer) which is passively absorbed by diffusion did not release GIP.	Mannose	0-7	complement C2	Canis lupus familiaris	9-12
6305937-11	1983	These studies demonstrate that although most of the "high uptake" enzyme in beta-glucuronidase from human spleen binds to receptors through phosphomonoesters of mannose, a significant fraction can interact with immobilized phosphomannosyl receptor and be taken up by fibroblasts through interactions involving mannose 6-phosphate in diester linkage with N-acetyl-D-glucosamine.	Mannose	161-168	glucuronidase beta	Homo sapiens	76-94
6222914-4	1983	The substrate for these studies was bovine rhodopsin labeled by in vitro techniques with [3H]-glucosamine or [3H]-mannose, the former being the derivative most extensively examined.	Mannose	114-121	rhodopsin	Bos taurus	43-52
6304338-5	1983	Second, we characterized the [(3)H]mannose-labeled tryptic peptides of pgD-1 and pgD-2.	Mannose	35-42	phosphoglycerate dehydrogenase	Homo sapiens	71-74
6304338-5	1983	Second, we characterized the [(3)H]mannose-labeled tryptic peptides of pgD-1 and pgD-2.	Mannose	35-42	prostaglandin D2 synthase	Homo sapiens	81-86
6854740-6	1983	Although external labeling with [3H]borohydride and metabolic labeling with [3H]glucosamine suggested that all three proteins were glycosylated, only E1 and E2b were efficiently labeled with [3H]mannose.	Mannose	195-202	dihydrolipoamide branched chain transacylase E2	Homo sapiens	157-160
6882370-8	1983	The present results indicate that the lactoferrin-clearance pathway is distinct from several pathways mediating glycoprotein clearance through recognition of terminal galactose, fucose, N-acetylglucosamine or mannose.	Mannose	209-216	lactotransferrin	Mus musculus	38-49
6840091-2	1983	Direct evidence is given for the presence of glucose, mannose and galactose as the products of hydrolysis of hemoglobins A1a1, A1a2, A1b, A1c and A0.	Mannose	54-61	syntrophin beta 1	Homo sapiens	133-136
6302214-6	1983	Both glucosamine and mannose were components of M26 to M34 but [3H]fucose appeared to be associated mainly with M34.	Mannose	21-28	olfactory receptor family 10 subfamily D member 1	Mus musculus	55-58
6847200-1	1983	Cellular distribution in rat livers of the mannan-binding protein, a liver lectin specific for mannose and N-acetylglucosamine was investigated.	Mannose	95-102	mannose binding lectin 1	Rattus norvegicus	43-65
6847200-5	1983	The receptor resembled the mannan-binding protein in its high affinity for mannan, requirement of Ca2+ for binding, and specificity for mannose and N-acetylglucosamine.	Mannose	136-143	mannose binding lectin 1	Rattus norvegicus	27-49
6403327-6	1983	Incubation of various 35S-labeled alpha forms with excess unlabeled TSH beta showed high combining activity for intracellular alpha with two high mannose units, intermediate activity for media alpha with two complex units, and low activity for intracellular alpha with one high mannose unit or nonglycosylated media alpha.	Mannose	146-153	thyroid stimulating hormone, beta subunit	Mus musculus	68-76
6403327-6	1983	Incubation of various 35S-labeled alpha forms with excess unlabeled TSH beta showed high combining activity for intracellular alpha with two high mannose units, intermediate activity for media alpha with two complex units, and low activity for intracellular alpha with one high mannose unit or nonglycosylated media alpha.	Mannose	278-285	thyroid stimulating hormone, beta subunit	Mus musculus	68-76
6223177-2	1983	The results suggest normal oligosaccharide side chains of high mannose type on lysosomal enzymes in alpha 1-antitrypsin (AAT) deficiency.	Mannose	63-70	serpin family A member 1	Homo sapiens	100-119
6132551-8	1983	The two allelic forms of the arylsulfatase A polypeptides were converted into a 57-kDa form by endo-beta-N-acetylglucosaminidase H, an enzyme specifically removing asparagine-linked oligosaccharides of the high-mannose (and hybrid) type.	Mannose	211-218	arylsulfatase A	Homo sapiens	29-44
6401730-3	1983	Levels of mannose ranged from 0.3 to 1.7 mol/mol of cytochrome P-450 whereas levels of galactose were less than or equal to 0.2 mol/mol of cytochrome P-450 for the five hemoproteins.	Mannose	10-17	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	52-68
6337129-1	1983	The lipid-linked oligosaccharide Glc3-Man9(GlcNAc)2 (Glc, glucose; Man, mannose; GlcNAc, N-acetylglucosamine) serves as a precursor for the biosynthesis of the inner core portion of the asparagine-linked polysaccharide of Saccharomyces cerevisiae mannoproteins.	Mannose	72-79	mannosidase alpha class 1A member 1	Homo sapiens	38-51
6833882-6	1983	We have determined that apoA-IV is a glycoprotein containing 6% carbohydrate by weight (mannose 1.8%, galactose 1.55%, N-acetyl glucosamine 1.55%, sialic acid 1.1%).	Mannose	88-95	apolipoprotein A4	Homo sapiens	24-31
6578391-9	1983	The lectin affinity of P24 derived from lymphoblasts is consistent with the presence of N-linked oligosaccharide chains having N-acetyl glucosamine residues, a mannose core, and a terminal D-galactose.	Mannose	160-167	transmembrane p24 trafficking protein 2	Homo sapiens	23-26
6346428-4	1983	Biosynthetic studies showing the incorporation of all four labeled monosaccharides (fucose, mannose, galactose and glucosamine) into the two major subunits of the insulin receptor suggested that both subunits were likely to contain carbohydrate chains of the complex, N-linked type.	Mannose	92-99	insulin receptor	Homo sapiens	163-179
6757247-7	1982	Invertase Man8GlcNAc (B) and Man9GlcNAc (C) were homogeneous compounds, which differed from the Man9GlcNAc (A) of thyroglobulin by the absence of a specific terminal alpha 1,2-linked mannose residue.	Mannose	183-190	mannosidase alpha class 1A member 1	Homo sapiens	29-33
6819087-4	1982	These results suggest that ZP2 is synthesized as an 81 kd polypeptide chain that is first "core"-glycosylated at asparagine residues with high-mannose-type oligosaccharides, giving rise to a 91 kd intermediate (Endo-H-sensitive), and then processed to complex-type oligosaccharides prior to secretion as mature, 120 kd ZP2 (Endo H-insensitive).	Mannose	143-150	zona pellucida glycoprotein 2	Homo sapiens	27-30
6959991-7	1982	Analysis of the carbohydrates by gas-liquid chromatography demonstrated that the carbohydrate chains of arylsulfatase C were rich in mannose and N-acetyl-glucosamine, suggesting that they are the high mannose-type.	Mannose	133-140	steroid sulfatase	Rattus norvegicus	104-119
6959991-7	1982	Analysis of the carbohydrates by gas-liquid chromatography demonstrated that the carbohydrate chains of arylsulfatase C were rich in mannose and N-acetyl-glucosamine, suggesting that they are the high mannose-type.	Mannose	201-208	steroid sulfatase	Rattus norvegicus	104-119
6292487-4	1982	These results suggested that the oligosaccharide chains of pgC(105) were primarily of the simple high-mannose type.	Mannose	102-109	progastricsin	Homo sapiens	59-62
6815785-2	1982	The mannose-binding lectin obtained from Lens culinaris (LCL) was a particularly efficient inducer of trypsin-sensitive antiviral activity, which qualified as IFN-gamma because it was 90-95% destroyed by pH 2 treatment but not neutralized by anti-IFN-gamma antibodies.	Mannose	4-11	interferon alpha 1	Homo sapiens	159-162
6815785-2	1982	The mannose-binding lectin obtained from Lens culinaris (LCL) was a particularly efficient inducer of trypsin-sensitive antiviral activity, which qualified as IFN-gamma because it was 90-95% destroyed by pH 2 treatment but not neutralized by anti-IFN-gamma antibodies.	Mannose	4-11	interferon alpha 1	Homo sapiens	247-250
6286683-3	1982	32Pi introduced into MEP by metabolic labeling of intact cells is exclusively associated with asparagine-linked oligosaccharides as indicated by sensitivity to endohexosaminidase H. Labeling studies utilizing [2-3H]mannose indicate that approximately one-fifth of the mannose residues of MEP are phosphorylated.	Mannose	215-222	cathepsin L	Mus musculus	21-24
6286683-3	1982	32Pi introduced into MEP by metabolic labeling of intact cells is exclusively associated with asparagine-linked oligosaccharides as indicated by sensitivity to endohexosaminidase H. Labeling studies utilizing [2-3H]mannose indicate that approximately one-fifth of the mannose residues of MEP are phosphorylated.	Mannose	268-275	cathepsin L	Mus musculus	21-24
6809759-8	1982	In addition, there was a minor specie of high mannose-type oligosaccharide bearing 5 mannose residues with an alpha 1,6-linked fucose on the GlcNAcol.	Mannose	46-53	adrenoceptor alpha 1D	Homo sapiens	110-117
6289902-3	1982	The activity on mannose was due to a highly specific mannokinase (ATP:D-mannose 6-phosphotransferase, EC 2.7.1.7) which has been separated from the glucokinase by Ultrogel AcA 54 gel filtration chromatography.	Mannose	16-23	glucokinase	Homo sapiens	148-159
6289902-3	1982	The activity on mannose was due to a highly specific mannokinase (ATP:D-mannose 6-phosphotransferase, EC 2.7.1.7) which has been separated from the glucokinase by Ultrogel AcA 54 gel filtration chromatography.	Mannose	16-23	small nucleolar RNA, H/ACA box 54	Homo sapiens	172-178
6954519-4	1982	The inability of glucosamine and mannose to promote a transport curb in the PGI strain must be ascribed to the fact that the 6-esters of these aldohexoses are converted by their own specific deaminase and isomerase to fructose 6-phosphate, which initiates the pyruvate-tricarboxylate energy-yielding pathway but cannot be converted to glucose 6-phosphate in the mutant.	Mannose	33-40	glucose-6-phosphate isomerase	Cricetulus griseus	76-79
6802821-4	1982	Whereas the mnn2 mannoprotein yields a core composed of 6 fragments that differ in size from each other by single mannose units, only the two smallest species predominate in the mnn1 mnn2 preparation.	Mannose	114-121	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	12-16
6802821-13	1982	Detailed analysis of the major core oligosaccharide from the mnn1 mnn2 mutant revealed that the two mannoses in alpha 1 leads to 3 linkage to the backbone were adjacent to each other and that the oligosacccharide is nearly identical with one isolated from chinese hamster ovary cell membranes (Li, E., and Kornfeld, S. (1979) J. Biol.	Mannose	100-108	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	61-65
6802821-13	1982	Detailed analysis of the major core oligosaccharide from the mnn1 mnn2 mutant revealed that the two mannoses in alpha 1 leads to 3 linkage to the backbone were adjacent to each other and that the oligosacccharide is nearly identical with one isolated from chinese hamster ovary cell membranes (Li, E., and Kornfeld, S. (1979) J. Biol.	Mannose	100-108	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	66-70
6949986-2	1982	SDS-PAGE of 3H-mannose-labeled I-Ak immunoprecipitates revealed that the alpha-chain peak was divided into three regions (alpha 1, alpha 2, and alpha 3), each of which migrated as a distinct individual band when isolated and reelectrophoresed.	Mannose	15-22	cholinergic receptor, nicotinic, alpha polypeptide 3	Mus musculus	122-151
6949986-7	1982	Our results suggest that alpha 1 and alpha 2 have fucose and sialic acid and thus possess complex type oligosaccharides, whereas alpha 3 lacks these sugars and possess high mannose-type saccharides.	Mannose	173-180	cholinergic receptor, nicotinic, alpha polypeptide 3	Mus musculus	129-136
7068641-4	1982	The beta-glucuronidase-derived phosphorylated oligosaccharides are all high mannose-type oligosaccharides whose linkages correspond to previously described prototypical high mannose structures.	Mannose	76-83	glucuronidase beta	Homo sapiens	4-22
7068641-4	1982	The beta-glucuronidase-derived phosphorylated oligosaccharides are all high mannose-type oligosaccharides whose linkages correspond to previously described prototypical high mannose structures.	Mannose	174-181	glucuronidase beta	Homo sapiens	4-22
7042570-6	1982	Nine enterotoxigenic strains of serotypes O7, O15, O25, O115, and O128 gave mannose-resistant hemagglutination of human or calf erythrocytes but lacked CFA/I or CFA/II.	Mannose	76-83	immunoglobulin kappa variable 2-36 (pseudogene)	Homo sapiens	46-49
6283141-6	1982	Similar analysis of GP31 and Gp36 labeled with [3H] mannose showed that the partial proteolytic fragments unique to these proteins were glycosylated.	Mannose	52-59	podoplanin	Homo sapiens	29-33
7037780-9	1982	These results indicate that the alg1-1 mutant is blocked specifically in the addition of the first mannose residue to the lipid-linked oligosaccharide precursor.	Mannose	99-106	ALG11 alpha-1,2-mannosyltransferase	Homo sapiens	32-38
7041974-1	1982	Michaelis constants for MgATP with yeast hexokinase vary from 28 microM with D-mannose to above 4 mM for the slow ATPase reaction, with the different values reflecting the degree of synergism in binding of MgATP and the sugar substrate.	Mannose	77-86	hexokinase	Saccharomyces cerevisiae S288C	41-51
6276375-4	1982	Specificity of the enzyme was evaluated by comparing the effects of mannose and glucose as phosphate acceptors in the phosphotransferase reaction catalyzed by glucose-6-phosphatase.	Mannose	68-75	glucose-6-phosphatase catalytic subunit 1	Homo sapiens	159-180
6276375-5	1982	Untreated glucose-6-phosphatase discriminates against mannose as compared with glucose in that mannose and glucose bind to the enzyme-P intermediate of untreated enzyme, but mannose is not an acceptor of Pi.	Mannose	54-61	glucose-6-phosphatase catalytic subunit 1	Homo sapiens	10-31
6276375-5	1982	Untreated glucose-6-phosphatase discriminates against mannose as compared with glucose in that mannose and glucose bind to the enzyme-P intermediate of untreated enzyme, but mannose is not an acceptor of Pi.	Mannose	95-102	glucose-6-phosphatase catalytic subunit 1	Homo sapiens	10-31
6276375-5	1982	Untreated glucose-6-phosphatase discriminates against mannose as compared with glucose in that mannose and glucose bind to the enzyme-P intermediate of untreated enzyme, but mannose is not an acceptor of Pi.	Mannose	95-102	glucose-6-phosphatase catalytic subunit 1	Homo sapiens	10-31
7053388-5	1982	In addition, a negligible amount of mannose was incorporated into intracellular or secreted vitellogenin.	Mannose	36-43	a1-a	Xenopus laevis	92-104
7053388-9	1982	In contrast to this finding, gas-liquid chromatography of the alditol acetate derivatives of the neutral hexoses of vitellogenin showed that mannose was indeed a major component of the vitellogenin oligosaccharide side chain.	Mannose	141-148	a1-a	Xenopus laevis	116-128
7053388-9	1982	In contrast to this finding, gas-liquid chromatography of the alditol acetate derivatives of the neutral hexoses of vitellogenin showed that mannose was indeed a major component of the vitellogenin oligosaccharide side chain.	Mannose	141-148	a1-a	Xenopus laevis	185-197
6119295-2	1982	The 3P(-) ETEC caused mannose-resistant hemagglutination, adhered to porcine intestinal epithelial cells in vitro, and produced pili.	Mannose	22-29	ETEC	Sus scrofa	10-14
6119295-10	1982	The results were interpreted to indicate that: (i) the epithelial adhesive and mannose-resistant hemagglutinating activities of the 3P(-) ETEC strains may be mediated by an antigen contained in material B; (ii) this antigen either is not pilus associated or is associated with pili that are not demonstrable by the methods used here; (iii) the 3P(-) ETEC strains produce type 1 pili which do not mediate their adhesion to intestinal epithelium of pigs.	Mannose	79-86	ETEC	Sus scrofa	138-142
7309750-11	1981	Proteolytic fragmentation of [3H]mannose-labeled beta-glucuronidase and partial digestion of [3H]leucine-labeled beta-glucuronidase with endo-beta-N-acetylglucosaminidase H suggest that there are 3 glycosylation sites per subunit.	Mannose	33-40	glucuronidase, beta	Mus musculus	49-67
6976315-3	1981	The intracellular form of Qa-1 is distinct from that of the TL glycoprotein in two ways: (1) its polypeptide backbone is approximately 5000 daltons shorter, and (2) it possesses three sites of high-mannose carbohydrate attachment, while TL has only one.	Mannose	198-205	histocompatibility 2, T region locus 23	Mus musculus	26-30
7310815-2	1981	These D-mannosyl peptide analogues were found to be potent competitive inhibitors of the uptake of 125I-labeled D-mannose-bovine serum albumin conjugate by rat alveolar macrophages.	Mannose	112-121	albumin	Rattus norvegicus	129-142
6171633-4	1981	Less glucosamine was demonstrated chemically in a alpha 1-M purified from rats in the first week of deficiency; alpha 1-M from more severely deficient rats showed significant depressions of mannose, galactose, and glucosamine.	Mannose	190-197	pregnancy-zone protein	Rattus norvegicus	112-121
6976784-5	1981	The glucose-dependent portion, supported by D-glucose and D-mannose oxidation, is inhibited by catalase (200 microgram/ml), amobarbital (1 mM) and hexose analogues that block D-glucose uptake.	Mannose	58-67	catalase	Rattus norvegicus	95-103
6790534-6	1981	Rat alpha-1-antitrypsin contains 14.3 residues/mol of N-acetylglucosamine, 5.0 residues/mol of mannose, 4.2 residues/mol of galactose, and 5.8 residues/mol of sialic acid.	Mannose	95-102	serpin family A member 1	Homo sapiens	4-23
7250048-5	1981	Circulating TG bound to Concanavalin A-Sepharose and had a normal MCR, indicating that mannose was present and galactose was not in terminal positions, both properties of glandular TG.	Mannose	87-94	thyroglobulin	Rattus norvegicus	12-14
7032516-5	1981	The inactivation of hexokinase by Procion Green H-4G is competitively inhibited by the adenine nucleotides ATP and ADP and the sugar substrates D-glucose, D-mannose and D-fructose but not by nonsubstrates such as D-arabinose and D-galactose.	Mannose	155-164	hexokinase	Saccharomyces cerevisiae S288C	20-30
7018700-0	1981	D-Mannose as a component of the macrophage surface receptor for macrophage-activating factor(MAF) in mice.	Mannose	0-9	avian musculoaponeurotic fibrosarcoma oncogene homolog	Mus musculus	93-96
6271905-7	1981	HA2 virus infection of MK cells increased fucose and glucose, and decreased mannose and galactose levels.	Mannose	76-83	keratin 32	Homo sapiens	0-3
7241383-4	1981	The blockade of toxin labeling was reversed when the Con-A-AChR complexes were treated with mannose (0.75 M).	Mannose	92-99	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	59-63
7241383-7	1981	We conclude that receptors from denervated rat muscle which bind Con-A (85% of the total AChR) contain two major subpopulations of AChR in the approximate proportions 6:4 that can be distinguished by interactions with lectins having specificity for mannose.	Mannose	249-256	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	131-135
7227306-3	1981	Furthermore, [3H]mannose was incorporated into the 70,000 Mr peak, which corresponds to the parathyroid secretory protein (PSP) recognized as a glycoprotein.	Mannose	17-24	phosphoserine phosphatase	Bos taurus	92-121
7227306-3	1981	Furthermore, [3H]mannose was incorporated into the 70,000 Mr peak, which corresponds to the parathyroid secretory protein (PSP) recognized as a glycoprotein.	Mannose	17-24	phosphoserine phosphatase	Bos taurus	123-126
7227306-8	1981	The incorporation of radioactive mannose into PSP was also greater at low extracellular calcium concentrations.	Mannose	33-40	phosphoserine phosphatase	Bos taurus	46-49
7012150-6	1981	The apparent ubiquitous distribution of mannan-binding protein in mammalian liver is consistent with the proposal that the binding protein is the cellular receptor mediating the hepatic uptake of glycoproteins terminated with mannose and/or N-acetylglucosamine residues.	Mannose	226-233	mannose binding lectin 1	Rattus norvegicus	40-62
7247048-3	1981	The acrosomal membrane fraction (Mf 1) contains about 10% carbohydrates which are composed of fucose, mannose, galactose, N-acetylglucosamine, N-acetylgalactosamine and N-acetylneuraminic acid in the molar ratio 1:3:6:4.5:2:3.	Mannose	102-109	flap structure-specific endonuclease 1	Homo sapiens	33-37
6783117-4	1981	Based on the alpha- and beta-mannosidase digestions and permethylation studies for the oligosaccharide moiety, and on the results obtained after sequential analysis of the peptide chain, the following structure is proposed for the mannose-rich IgM Du glycopeptide: (Formula: see text).	Mannose	231-238	mannosidase beta	Homo sapiens	13-40
7305921-3	1981	The positions of specific galactose residues and asparagine-linked carbohydrate chains containing specific mannose residues in epiglycanin, a glycoprotein of extended conformation from the surface of TA3 mouse mammary tumour cells, were observed in complexes with Ricinus communis toxin and concanavalin A respectively.	Mannose	107-114	mucin 21	Mus musculus	127-138
7305927-4	1981	The amniotic-fluid fibronectins had similar mannose and sialic acid contents to plasma fibronectin, but greater amounts of glucosamine, galactosamine, galactose and fucose.	Mannose	44-51	fibronectin 1	Homo sapiens	19-30
7021369-2	1981	It was shown that hexokinase contained inside permeabilized yeast cells can be used successfully in the phosphorylation of mannose for the production of mannose 6-phosphate.	Mannose	123-130	hexokinase	Saccharomyces cerevisiae S288C	18-28
7002931-5	1980	Proteinase A is a glycoprotein containing 7.5% mannose and 1% of glucosamine and galactosamine.	Mannose	47-54	proteinase A	Saccharomyces cerevisiae S288C	0-12
7459349-3	1980	On the basis of selective enzymatic and partial acid hydrolysis and 1H and 31P NMR studies, Man5P was shown to have the structure P leads to 6 alpha Man1 leads to 3 alpha Man1 leads to 2 alpha Man1 leads to 2 alpha Man1 leads to 2Man (where Man = D-mannopyranose).	Mannose	247-262	LEM domain containing 3	Homo sapiens	149-153
6263438-2	1980	Using an adenylyl cyclase deficient mutant (CA8306B) and a cyclic AMP receptor protein (CRP) deficient mutant (5333B) we have shown that the utilization of mannose is dependent on the cyclic AMP - CRP complex.	Mannose	156-163	catabolite gene activator protein	Escherichia coli	59-86
6263438-2	1980	Using an adenylyl cyclase deficient mutant (CA8306B) and a cyclic AMP receptor protein (CRP) deficient mutant (5333B) we have shown that the utilization of mannose is dependent on the cyclic AMP - CRP complex.	Mannose	156-163	catabolite gene activator protein	Escherichia coli	88-91
6263438-2	1980	Using an adenylyl cyclase deficient mutant (CA8306B) and a cyclic AMP receptor protein (CRP) deficient mutant (5333B) we have shown that the utilization of mannose is dependent on the cyclic AMP - CRP complex.	Mannose	156-163	catabolite gene activator protein	Escherichia coli	197-200
7438137-3	1980	The capsular polysaccharide from Klebsiella K74 is composed of D-glucuronic acid, D-galactose, and D-mannose, and this chemotype includes a total of seven strains, of which four have 1-carboxyethylidene groups (pyruvic acid acetals).	Mannose	99-108	keratin 74	Homo sapiens	44-47
7236228-1	1980	The mannose- and N-acetylglucosamine-specific pathway for the clearance of mammalian glycoproteins has been characterized by using 125I-labelled neoglycoproteins, glycosidase-treated orosomucoid and lysosomal glycosidases (beta-glucuronidase and beta-N-acetylglucosaminidase) as probes.	Mannose	4-11	glucuronidase beta	Homo sapiens	223-241
7236228-1	1980	The mannose- and N-acetylglucosamine-specific pathway for the clearance of mammalian glycoproteins has been characterized by using 125I-labelled neoglycoproteins, glycosidase-treated orosomucoid and lysosomal glycosidases (beta-glucuronidase and beta-N-acetylglucosaminidase) as probes.	Mannose	4-11	O-GlcNAcase	Homo sapiens	246-274
6774767-4	1980	Incorporated mannose was removed only at early time points, suggesting that the structure of fibronectin oligosaccharides was altered due to processing.	Mannose	13-20	fibronectin 1	Homo sapiens	93-104
6774767-11	1980	We conclude that the carbohydrate portion of fibronectin is synthesized as a "high-mannose" intermediate and is subsequently processed to give the characteristic "complex" oligosaccharide chains of fibronectin.	Mannose	83-90	fibronectin 1	Homo sapiens	45-56
6780161-5	1980	This idea was confirmed in the case of alpha 1-acid glycoprotein by isolation of a high mannose containing precursor species of alpha 1-acid glycoprotein from rough fractions of liver.	Mannose	88-95	orosomucoid 1	Rattus norvegicus	39-64
6780161-5	1980	This idea was confirmed in the case of alpha 1-acid glycoprotein by isolation of a high mannose containing precursor species of alpha 1-acid glycoprotein from rough fractions of liver.	Mannose	88-95	orosomucoid 1	Rattus norvegicus	128-153
6780161-7	1980	It is proposed that the high mannose precursor is a form of alpha 1-acid glycoprotein that exists at an early stage in assembly of the glycoprotein and which contains largely unprocessed carbohydrate chains.	Mannose	29-36	orosomucoid 1	Rattus norvegicus	60-85
6780161-8	1980	In addition, evidence is presented from amino acid analyses and gel electrophoresis of the high mannose precursor and another fraction from which it is formed by limited tryptic treatment, that pro-forms of alpha 1-acid glycoprotein with extensions of the polypeptide chain may also exist.	Mannose	96-103	orosomucoid 1	Rattus norvegicus	207-232
6934545-0	1980	A defect in the structure of type I procollagen in a patient who had osteogenesis imperfecta: excess mannose in the COOH-terminal propeptide.	Mannose	101-108	collagen type I alpha 2 chain	Homo sapiens	29-47
6934545-2	1980	The type I procollagen from the patient"s fibroblasts contained 2-3 time more [3H]mannose than the type I procollagen from the normal fibroblasts.	Mannose	82-89	collagen type I alpha 2 chain	Homo sapiens	4-22
6934545-4	1980	Isolation of a collagenase-resistant peptide fragment from the type I procollagen showed that the excess mannose was located in the COOH-terminal propeptide of the protein.	Mannose	105-112	collagen type I alpha 2 chain	Homo sapiens	63-81
7248356-2	1980	It was found that similar to bovine rhodopsin, the protein from wall-eyed pollock contains in its carbohydrate moiety only two types of monosaccharides, i. e. mannose and glucosamine (1,78 +/- 0,13 moles of mannose per one mole of glucosamine).	Mannose	159-166	rhodopsin	Bos taurus	36-45
7248356-3	1980	One mole of rhodopsin contains 9,43 +/- 1,5 moles of mannose and 5,3 moles of glucosamine.	Mannose	53-60	rhodopsin	Bos taurus	12-21
6774978-5	1980	Five oligosaccharides (F1, G, H1, I, and J) were shown to have typical high-mannose type structures (Man alpha 1-)n.Man beta 1-4GlcNAc beta 1-GlcNAc, with n-values of 8, 7, 6, 5, and 4, respectively.	Mannose	76-83	filamin B	Homo sapiens	23-42
6774978-5	1980	Five oligosaccharides (F1, G, H1, I, and J) were shown to have typical high-mannose type structures (Man alpha 1-)n.Man beta 1-4GlcNAc beta 1-GlcNAc, with n-values of 8, 7, 6, 5, and 4, respectively.	Mannose	76-83	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	135-141
6998814-6	1980	Insulin secretion was also stimulated by mannose, leucine, alpha-ketoisocaproate, dihydroxyacetone and 3-hydroxybutyrate, but not by fructose or N-acetyl-glucosamine.	Mannose	41-48	insulin	Homo sapiens	0-7
6159379-3	1980	In comparison, the lowest unspecific tissue adsorption and staining was obtained with Protein A-peroxidase in buffer containing glucose and mannose.	Mannose	140-147	AT695_RS02070	Staphylococcus aureus	96-106
7373053-3	1980	Analyses of the oligosaccharide units showed that P-C4 (185) appears to contain both a "complex" and a "high mannose" carbohydrate group, the alpha-chain a "complex" group and the beta-chain a "high mannose" carbohydrate unit.	Mannose	109-116	SUB1 homolog, transcriptional regulator	Mus musculus	50-54
7373053-3	1980	Analyses of the oligosaccharide units showed that P-C4 (185) appears to contain both a "complex" and a "high mannose" carbohydrate group, the alpha-chain a "complex" group and the beta-chain a "high mannose" carbohydrate unit.	Mannose	199-206	SUB1 homolog, transcriptional regulator	Mus musculus	50-54
16661328-8	1980	Since these four lectins have similar sugarbinding properties but different physical properties, the variation in bindings of these lectins to various Rhizobium strains indicates that binding of lectin to Rhizobium is determined not only by the sugar specificity of the lectin but also by its physical characteristics.The binding of lentil lectin and concanavalin A to R. leguminosarum 128C53 could be inhibited by glucose, fructose, and mannose.	Mannose	438-445	LOW QUALITY PROTEIN: lectin	Glycine max	17-23
16661328-8	1980	Since these four lectins have similar sugarbinding properties but different physical properties, the variation in bindings of these lectins to various Rhizobium strains indicates that binding of lectin to Rhizobium is determined not only by the sugar specificity of the lectin but also by its physical characteristics.The binding of lentil lectin and concanavalin A to R. leguminosarum 128C53 could be inhibited by glucose, fructose, and mannose.	Mannose	438-445	LOW QUALITY PROTEIN: lectin	Glycine max	132-138
16661328-8	1980	Since these four lectins have similar sugarbinding properties but different physical properties, the variation in bindings of these lectins to various Rhizobium strains indicates that binding of lectin to Rhizobium is determined not only by the sugar specificity of the lectin but also by its physical characteristics.The binding of lentil lectin and concanavalin A to R. leguminosarum 128C53 could be inhibited by glucose, fructose, and mannose.	Mannose	438-445	LOW QUALITY PROTEIN: lectin	Glycine max	132-138
7407676-0	1980	Mannose containing glycopeptides of cells derived from human teratocarcinoma (line PA 1).	Mannose	0-7	PAXIP1 associated glutamate rich protein 1	Homo sapiens	83-87
6766954-4	1980	Furthermore, although assimilation of beta-galactosidase was inhibited by mannose, methyl mannosides, mannosyl alpha 1 leads to 2 mannose, and mannose-6-phosphate, these compounds did not detectably inhibit the assimilation of beta-glucuronidase.	Mannose	74-81	galactosidase beta 1	Bos taurus	38-56
6766954-4	1980	Furthermore, although assimilation of beta-galactosidase was inhibited by mannose, methyl mannosides, mannosyl alpha 1 leads to 2 mannose, and mannose-6-phosphate, these compounds did not detectably inhibit the assimilation of beta-glucuronidase.	Mannose	130-137	galactosidase beta 1	Bos taurus	38-56
24310138-10	1980	The main neutral sugar was mannose in alpha-glucosidase I, and glucose in alpha-glucosidase II.	Mannose	27-34	alpha-glucosidase	Beta vulgaris subsp. vulgaris	38-55
7362830-4	1980	Antithrombin III was a glycoprotein containing 3.6% glucosamine, 0.2% fucose, 2.5% mannose, 1.6% galactose and 3.9% sialic acid.	Mannose	83-90	serpin family C member 1	Rattus norvegicus	0-16
7439928-4	1980	The fraction eluted by 0.2 M mannose was found to be as active as the crude Nip preparation in inhibiting EL4 tumour cell proliferation in vitro.	Mannose	29-36	epilepsy 4	Mus musculus	106-109
508810-4	1979	A reductive alkylation treatment of the unpurified mucin fraction followed by Sepharose CL-4B chromatography removed contaminating protein and most of the mannose-containing material from the mucin fraction.	Mannose	155-162	solute carrier family 13 member 2	Rattus norvegicus	51-56
508810-4	1979	A reductive alkylation treatment of the unpurified mucin fraction followed by Sepharose CL-4B chromatography removed contaminating protein and most of the mannose-containing material from the mucin fraction.	Mannose	155-162	solute carrier family 13 member 2	Rattus norvegicus	192-197
479351-10	1979	From these studies we conclude that 1) galactose does not elicit IRI secretion per se, yet, like glucose, potentiates GIP and IRI secretion; 2) mannose, despite weak transport across gut or kidney, evokes significant betacytotropic effects; and 3) mannose- and fructose-induced enhancement of glucose disposal might be mediated by a factor(s) other than GIP.	Mannose	144-151	gastric inhibitory polypeptide	Homo sapiens	354-357
314662-2	1979	The carbohydrate content of individual factor VIII bands, measured by reaction with dansyl hydrazine or binding of glucose/mannose specific concanavalin A, was not directly related to the size or von Willebrand activity of factor VIII oligomers.	Mannose	123-130	coagulation factor VIII	Bos taurus	39-50
389723-2	1979	Insulin release and synthesis were stimulated by glucose or mannose but not by allose, altrose, gulose, idose, galactose or talose.	Mannose	60-67	insulin	Homo sapiens	0-7
116230-11	1979	These observations suggest that the recognition marker of beta-galactosidase contains alpha1,2-linked mannose 6-phosphate; terminal alpha1,2-linked mannose residues are known to occur in the high-mannose type oligosaccharides present on beta-galactosidase.	Mannose	102-109	galactosidase beta 1	Bos taurus	58-76
496912-3	1979	The inhibition of endocytosis by mannan indicates that the beta-N-acetylglucosaminidase from mucolipidosis-II and -III patients is recognized by cell-surface receptors specific for mannose.	Mannose	181-188	O-GlcNAcase	Homo sapiens	59-87
315316-4	1979	Furthermore, populations of cytolytic cells which had been pretreated with doses of tunicamycin sufficient to block the incorporation of mannose (or 2-DG) into glycoproteins were still fully susceptible to inhibition by 2-DG.	Mannose	137-144	olfactory receptor family 7 subfamily E member 55 pseudogene	Homo sapiens	146-153
288065-7	1979	Mannan and partially deglycosylated glycoproteins bearing terminal nonreducing N-acetylglucosamine or mannose residues were shown to be potent inhibitors of the cellular uptake of (125)I-beta-hexosaminidase; native orosomucoid and desialylated (galactoseterminated) orosomucoid were not inhibitory.	Mannose	102-109	O-GlcNAcase	Homo sapiens	187-206
288065-8	1979	Of six simple sugars tested, including N-acetylglucosamine, only mannose was an effective inhibitor of the cellular uptake of (125)I-beta-hexosaminidase.	Mannose	65-72	O-GlcNAcase	Homo sapiens	133-152
114170-2	1979	Adsorptive endocytosis of alpha-N-acetylglucosaminidase from human urine by isolated rat hepatocytes is inhibited by glycoproteins, polysaccharides and sugars that are known to bind to cell-surface receptors specific for either terminal galactose/N-acetylgalactosamine residues, terminal mannose residues or mannose 6-phosphate residues.	Mannose	288-295	N-acetyl-alpha-glucosaminidase	Homo sapiens	26-55
114170-4	1979	Recognition of alpha-N-acetylglucosaminidase via receptors recognizing mannose 6-phosphate residues is lost after treatment of the enzyme with alkaline phosphatase and endoglucosaminidase H. The effect of endoglucosaminidase H supports the view that the mannose 6-phosphate residues reside in N-glycosidically linked oligosaccharide side chains of the high-mannose type.	Mannose	71-78	N-acetyl-alpha-glucosaminidase	Homo sapiens	15-44
114170-5	1979	The weak inhibition of endocytosis produced by compounds known to interact with cell-surface receptors specific for mannose residues suggests that this recognition system plays only a minor role in the endocytosis of lysosomal alpha-N-acetylglucosaminidase by hepatocytes.	Mannose	116-123	N-acetyl-alpha-glucosaminidase	Homo sapiens	227-256
446474-9	1979	Cathepsin D-I contained 6.6% carbohydrate, consisting of mannose, glucose, galactose, fucose and glucosamine in a ratio of 8:2:1:1:5 with a trace of sialic acid.	Mannose	57-64	cathepsin D	Rattus norvegicus	0-11
428391-9	1979	Loss of alpha-N-acetylglucosaminidase endocytosis after treatment with endoglucosaminidase H indicated that the recognition site of alpha-N-acetylglucosaminidase is located on N-glycosidically linked oligosaccharides of the high mannose type.	Mannose	229-236	N-acetyl-alpha-glucosaminidase	Homo sapiens	8-37
428391-9	1979	Loss of alpha-N-acetylglucosaminidase endocytosis after treatment with endoglucosaminidase H indicated that the recognition site of alpha-N-acetylglucosaminidase is located on N-glycosidically linked oligosaccharides of the high mannose type.	Mannose	229-236	N-acetyl-alpha-glucosaminidase	Homo sapiens	132-161
286306-1	1979	Placental RNA has previously been shown to direct the synthesis of an asparagine-linked mannose-rich glycosylated form of the alpha subunit of human chorionic gonadotropin (hCG-alpha) in lysates derived from mouse ascites tumor cells.	Mannose	88-95	chromogranin A	Homo sapiens	173-182
83994-4	1979	Features of this structure not previously established include the presence of 2 residues of alpha2,3- and 1 residue of alpha2,6-linked sialic acid and their location relative to the mannose branch points.	Mannose	182-189	adrenoceptor alpha 1D	Homo sapiens	92-107
6726182-6	1984	In infected cells, the counterparts to E1 and E2 were labelled with [3H]mannose and both migrated in gels as sharp bands, indicating that the heterogeneity observed in virion E2 was produced during virus maturation.	Mannose	72-79	small nucleolar RNA, H/ACA box 73A	Homo sapiens	39-48
84796-1	1979	Specificity and cross-reactivity of factor O9 serum and of antibodies against tyvelose (Formula: see text) mannose coupled to bovine serum albumin.	Mannose	107-114	albumin	Oryctolagus cuniculus	133-146
569630-1	1978	Receptor-mediated endocytosis of alpha-N-acetylglucosaminidase by cultured epithelial rat liver cells is inhibited by mannose, L-fucose and most effectively by mannose 6-phosphate.	Mannose	118-125	N-acetyl-alpha-glucosaminidase	Rattus norvegicus	33-62
308696-0	1978	alpha1-Antitrypsin: the presence of excess mannose in the Z variant isolated from liver.	Mannose	43-50	serpin family A member 1	Homo sapiens	0-18
104712-22	1978	beta-Galactosidase A2 contained 7.5% carbohydrate by weight and sialic acid, D-galactose, D-glucosamine and D-mannose were present in the molar proportions 1.1:1.0:1.7:2.7.	Mannose	108-117	galactosidase beta 1	Homo sapiens	0-18
99447-2	1978	The carbohydrate composition of TBG (14.6% by weight) consists of mannose, galactose, N-acetylglucosamine, and N-acetylneuraminic acid in the molar ratios of 11:9:16:10 per mol of glycoprotein.	Mannose	66-73	serpin family A member 7	Homo sapiens	32-35
355255-2	1978	A homogenate of mechanically broken, freshly grown Saccharomyces cerevisiae X2180 cells catalyzes the transfer of mannosylphosphate units from guanosine diphosphate mannose to reduced alpha1 leads to 2-[3H]mannotetraose to yield reduced mannosylphosphoryl [3H]-mannotetraose.	Mannose	165-172	transcriptional co-activator mating type protein alpha	Saccharomyces cerevisiae S288C	184-190
365173-11	1978	It is suggested that glucose, and to some extent mannose, preserves the glucoreceptor mechanism for insulin secretion by influencing an early stage in glucose metabolism, presumably glucokinase activity.	Mannose	49-56	glucokinase	Mus musculus	182-193
687592-2	1978	The composition and molecular weight of the Pronase glycopeptides revealed that rabbit transferrin contains two heteropolysaccharide units, each composed of 2 sialic acid residues, 2 galactose residues, 3 mannose residues, and 4-N-acetylglucosamine residues.	Mannose	205-212	serotransferrin	Oryctolagus cuniculus	87-98
618863-2	1978	Human antithrombin III was found to contain covalently linked N-acetylglucosamine, mannose, galactose, and sialic acid in a molar ratio of approximately 1:1:0.6:1.	Mannose	83-90	serpin family C member 1	Homo sapiens	6-22
80383-3	1978	Whereas CFA/I mediates mannose-resistant hemagglutination of human group A erythrocytes, CFA/II does not.	Mannose	23-30	tubulin folding cofactor A	Homo sapiens	8-11
80383-4	1978	CFA/II mediates mannose-resistant hemagglutination of bovine erythrocytes, and mannose-resistant hemagglutination is rapid only at reduced temperature (4 degrees C).	Mannose	16-23	tubulin folding cofactor A	Homo sapiens	0-3
668697-5	1978	The chemical shifts of the anomeric and mannose H-2 protons give information about the type of glycan structure (mono-, bi-, triantennary) and the presence of terminal sialic acid at each of the antennas.	Mannose	40-47	relaxin 2	Homo sapiens	48-51
663933-1	1978	A mannose-containing sialooligosaccharide has been isolated from the urine of a patient with a newly recognized mucolipidosis which showed a low liver beta-galactosidase activity and hyperglycopeptiduria.	Mannose	2-9	galactosidase beta 1	Homo sapiens	151-169
102578-6	1978	Placenta alpha-N-acetylglucosaminidase has an apparent molecular weight of 304 000 and contains 23.4% carbohydrate consisting of glucose, galactose, mannose, hexosamines and neuraminic acid.	Mannose	149-156	N-acetyl-alpha-glucosaminidase	Homo sapiens	9-38
646806-3	1978	The inhibition of alpha-N-acetylglucosaminidase endocytosis by mannose, p-nitrophenyl alpha-d-mannoside and mannose 6-phosphate was shown to be competitive.	Mannose	63-70	N-acetyl-alpha-glucosaminidase	Homo sapiens	18-47
23338136-4	1978	Glucose and mannose in approximately equimolar amounts were identified as the main sugars of the glycoprotein ATPase, thus confirming previous structural studies.	Mannose	12-19	dynein axonemal heavy chain 8	Homo sapiens	110-116
845158-10	1977	The beta-mannosidase also released [14C]mannose from the Man-GlcNAc-GlcNAc trisaccharide isolated from the lipid-linked oligosaccharides of aorta and released mannose from the disaccharides, Man-(beta1 leads to 4)GlcNAc and Man-(beta1 leads to 4)ManNAc.	Mannose	40-47	mannosidase beta	Homo sapiens	4-20
562233-4	1977	Most of these peripheral sugar chains are linked to two inner D-mannose residues which are substituted at C-3 and C-6, and constitute branching points.	Mannose	64-71	complement C3	Homo sapiens	106-109
562233-4	1977	Most of these peripheral sugar chains are linked to two inner D-mannose residues which are substituted at C-3 and C-6, and constitute branching points.	Mannose	64-71	complement C6	Homo sapiens	114-117
32437-10	1978	The results of carbohydrate and lipid analyses indicated that the oxidoreductase is a glycolipoprotein with fucose, galactose, mannose, and glucosamine as the sugar components and cholesterol and sphingomyelin as the lipid constituents.	Mannose	127-134	thioredoxin reductase 1	Homo sapiens	66-80
845158-10	1977	The beta-mannosidase also released [14C]mannose from the Man-GlcNAc-GlcNAc trisaccharide isolated from the lipid-linked oligosaccharides of aorta and released mannose from the disaccharides, Man-(beta1 leads to 4)GlcNAc and Man-(beta1 leads to 4)ManNAc.	Mannose	40-47	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	196-201
845158-10	1977	The beta-mannosidase also released [14C]mannose from the Man-GlcNAc-GlcNAc trisaccharide isolated from the lipid-linked oligosaccharides of aorta and released mannose from the disaccharides, Man-(beta1 leads to 4)GlcNAc and Man-(beta1 leads to 4)ManNAc.	Mannose	40-47	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	229-234
845158-10	1977	The beta-mannosidase also released [14C]mannose from the Man-GlcNAc-GlcNAc trisaccharide isolated from the lipid-linked oligosaccharides of aorta and released mannose from the disaccharides, Man-(beta1 leads to 4)GlcNAc and Man-(beta1 leads to 4)ManNAc.	Mannose	159-166	mannosidase beta	Homo sapiens	4-20
845158-10	1977	The beta-mannosidase also released [14C]mannose from the Man-GlcNAc-GlcNAc trisaccharide isolated from the lipid-linked oligosaccharides of aorta and released mannose from the disaccharides, Man-(beta1 leads to 4)GlcNAc and Man-(beta1 leads to 4)ManNAc.	Mannose	159-166	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	196-201
845158-10	1977	The beta-mannosidase also released [14C]mannose from the Man-GlcNAc-GlcNAc trisaccharide isolated from the lipid-linked oligosaccharides of aorta and released mannose from the disaccharides, Man-(beta1 leads to 4)GlcNAc and Man-(beta1 leads to 4)ManNAc.	Mannose	159-166	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	229-234
13840-6	1977	The Km for glucose of pea-seed glucokinase was 70 muM and the Km for mannose was 0.5 mM.	Mannose	69-76	glucokinase	Homo sapiens	31-42
14148-6	1977	The binding of thyroid peroxidase to Con A-agarose can be inhibited by sugars in the following order: alpha-methyl-D-mannoside greater than D-mannose greater than alpha-methyl-D-glucoside greater than D-glucose greater than D-galactose.	Mannose	140-149	thyroid peroxidase	Homo sapiens	15-33
868388-1	1977	Ultraviolet light (PRK-2) induces the formation of various amino acids (lysine, asparaginic, as well as traces of some other acids) in mannose, glucose and arabinose solutions containing various nitrates.	Mannose	135-142	protein kinase N2	Homo sapiens	19-24
73630-2	1977	Immunochemical studies indicate that oligomers of alpha1 yields to 2, alpha1 yields to 3, alpha1 yields to 6, and probably also alpha yields to 4 linked mannose residues of sperm carbohydrates are available for antibody binding.	Mannose	153-160	adrenoceptor alpha 1D	Homo sapiens	50-56
1254583-6	1976	Rhodopsin was found to have about 9 mol of mannose and 5 mol of glucosamine per mol of visual pigment.	Mannose	43-50	rhodopsin	Bos taurus	0-9
827294-0	1976	The role of glycosidically bound mannose in the assimilation of beta-galactosidase by generalized gangliosidosis fibroblasts.	Mannose	33-40	galactosidase beta 1	Homo sapiens	64-82
1002996-7	1976	Analysis of the carbohydrate moiety in C5a indicated 4 moles of glucosamine, 3 to 4 moles os sialic acid, 4 moles of mannose and 2 moles of galactose.	Mannose	117-124	complement C5a receptor 1	Homo sapiens	39-42
9199-4	1976	Thus, the aglycon group in the alpha anomers protects position 3, the axial HO-4 in galactopyranosides protects position 2, and the axial HO-2 in mannopyranosides protects position 4 from oxidation.	Mannose	146-162	heme oxygenase 2	Homo sapiens	138-142
949488-11	1976	It is concluded that mannose residues of lipoprotein lipase in heart homogenates and at the endothelial surface of heart capillaries are available to interact with a specific lectin.	Mannose	21-28	lipoprotein lipase	Rattus norvegicus	41-59
1260011-1	1976	A major glycoprotein 36 000 molecular weight) has been isolated from lung lavage of patients with alveolar proteinosis and found to contain five residues of hydroxyproline, fifty residues of glycine, three residues of methionine, 3 mol of sialic acid, 4.4 mol of mannose, 4.0 mol of galactose, 6.0 mol of glucosamine, and 1 mol of fucose.	Mannose	263-270	podoplanin	Homo sapiens	8-23
999941-10	1976	The BR protein contained glucosamine, mannose, galactose, fucose and sialic acids and the PAS-II protein contained glucosamine, mannose, galactose, fucose and glucose.	Mannose	128-135	peripheral myelin protein 22	Bos taurus	90-96
975107-6	1976	Significantly, even after 100% of the fucose and N-acetylneuraminic acid, 75% of the galactose, and 50% of the N-acetylglucosamine and mannose were destroyed by serial periodate oxidation (Smith degradation), the remaining portion of the CEA molecule lost no more antigenic activity than did control samples where periodate was omitted.	Mannose	135-142	CEA cell adhesion molecule 3	Homo sapiens	238-241
182683-12	1976	The actions of mannose on the glucose-6-phosphatase of intact microsomes fully support the postulated transport model.	Mannose	15-22	glucose-6-phosphatase catalytic subunit 1	Homo sapiens	30-51
1084886-7	1976	Specifically, the Z-type alpha-1-AT is deficient in 1 glucosamine residue, 3 neutral sugar residues (1 mannose and 2 galactose), and 2 sialic acid residues.	Mannose	103-110	serpin family A member 1	Homo sapiens	25-35
182183-16	1976	The carbohydrate moiety of ApoB contained mannose, galactose and galactosamine.	Mannose	42-49	apolipoprotein B	Homo sapiens	27-31
956159-6	1976	The molar ratios of the constituent neutral sugars of this glycoprotein (GP-1) are as follows: fucose 3, mannose 5, galactose 5, glucose 1, and xylose 1.	Mannose	105-112	GTP binding protein 1	Homo sapiens	73-77
57824-6	1976	Compositional analyses further indicated that the mannose content of various CEA fractions was directly correlated with Con A binding affinity, amino acid content, morphological type, and CEA specific activity.	Mannose	50-57	CEA cell adhesion molecule 3	Homo sapiens	77-80
57824-6	1976	Compositional analyses further indicated that the mannose content of various CEA fractions was directly correlated with Con A binding affinity, amino acid content, morphological type, and CEA specific activity.	Mannose	50-57	CEA cell adhesion molecule 3	Homo sapiens	188-191
1254583-7	1976	A molar ratio of mannose/glucosamine of about 2 was also found in samples of rhodopsin obtained from two other laboratories.	Mannose	17-24	rhodopsin	Bos taurus	77-86
56198-6	1976	Carbohydrate analysis demonstrated that ApoD is a glycoprotein with glucose, mannose, galactose, glucosamine, and sialic acid accounting for 18% of the dry weight of ApoD.	Mannose	77-84	apolipoprotein D	Homo sapiens	40-44
811665-5	1976	The mannanase acts on unbranched alpha1 leads to 6-mannan to produce mannose and alpha1 leads to 6-mannobiose, with the intermediate formation of alpha1 leads to 6-mannooligosaccharides of various sizes.	Mannose	69-76	transcriptional co-activator mating type protein alpha	Saccharomyces cerevisiae S288C	33-39
813583-7	1975	This finding indicates that the carbohydrate chain of human tyrosinase contains D-mannose.	Mannose	80-89	tyrosinase	Homo sapiens	60-70
788424-1	1976	Somatostatin inhibits in a dose-dependent manner the glucagon secretion in the presence of up to 5 mM glucose, whereas the suppressed glucagon release in the presence of greater than or equal to 10 mM glucose, 10 mM glyceraldehyde, 30 mM fructose or 30 mM mannose is characterized by an increase of hormone release under the influence of somatostatin.	Mannose	256-263	somatostatin	Rattus norvegicus	0-12
1183043-2	1975	Bovine adrenal medulla dopamine beta-hydroxylase, a glycoprotein with terminal mannose residues in carbohydrate moiety, did not precipitate with any lectins tested except concanavalin A.	Mannose	79-86	dopamine beta-hydroxylase	Bos taurus	23-48
1105568-4	1975	Free mannose is an acceptor for the alpha1 leads to 2-mannosyltransferase, the major product being alpha[14C]Man leads to 2Man.	Mannose	5-12	transcriptional co-activator mating type protein alpha	Saccharomyces cerevisiae S288C	36-42
240364-0	1975	Specific inhibition of endo-beta-N-acetylglucosaminidase D by mannose and simple mannosides.	Mannose	62-69	O-GlcNAcase	Homo sapiens	28-56
5773084-12	1969	It is believed that the more rapid utilization of mannose relative to glucose by intact hexokinase-deficient cells may be explained on the basis of the regulatory effect of the PMI reaction on the rate of mannose utilization.	Mannose	205-212	hexokinase 1	Homo sapiens	88-98
1170888-18	1975	On the other hand, GP-1 and GP-2 had nearly identical levels of carbohydrate, 45.1 and 48.0 wt %, and possessed essentially the same percent distribution of carbohydrates: sialic acid, 16.5 plus or minus 0.5; mannose, 10.3 plus or minus 0.4; glucosamine, 11.2 plus or minus 0.1; galactose, 7.9 plus or minus 0.3.	Mannose	209-216	glycoprotein 2	Bos taurus	19-32
5086108-0	1972	13 C magnetic resonance and structural studies on the mannose-containing polysaccharides of some Pichia and Hansenula spp.	Mannose	54-61	histocompatibility minor 13	Homo sapiens	118-121
5366873-0	1969	[Effects of mannose on insulin secretion].	Mannose	12-19	insulin	Homo sapiens	23-30
5773084-8	1969	When human erythrocytes are incubated with mannose rapid accumulation of Man-6-P occurs, a finding indicating that PMI and not hexokinase is the limiting enzyme in the over-all conversion of mannose to fructose by the red cell.	Mannose	43-50	mannose phosphate isomerase	Homo sapiens	115-118
5773084-8	1969	When human erythrocytes are incubated with mannose rapid accumulation of Man-6-P occurs, a finding indicating that PMI and not hexokinase is the limiting enzyme in the over-all conversion of mannose to fructose by the red cell.	Mannose	191-198	mannose phosphate isomerase	Homo sapiens	115-118
1097420-2	1975	The mnn2 mutation, which affects the addition to the polysaccharide backbone of the first side-chain D-mannose unit in alpha1-leads to2 linkage, was located on chromosome II linked to the centromere and the gall locus.	Mannose	101-110	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	4-8
4109596-2	1972	That some mannose and glucosamine residues are acquired by immunoglobulin precursor molecules was demonstrated by the detection of glucosamine and mannose in HH, HHL, and LHHL.	Mannose	10-17	RAB GTPase activating protein 1-like	Mus musculus	162-165
5773084-12	1969	It is believed that the more rapid utilization of mannose relative to glucose by intact hexokinase-deficient cells may be explained on the basis of the regulatory effect of the PMI reaction on the rate of mannose utilization.	Mannose	205-212	mannose phosphate isomerase	Homo sapiens	177-180
5773084-9	1969	The ratio of mannose utilization to glucose utilization in hexokinase-deficient cells was greater than normal, as has been reported previously.	Mannose	13-20	hexokinase 1	Homo sapiens	59-69
5773084-11	1969	Consequently, Man-6-P accumulated only approximately one-third as rapidly as normal in hexokinase-deficient cells incubated with mannose.	Mannose	129-136	hexokinase 1	Homo sapiens	87-97
33892066-8	2021	RESULTS: The average molecular weight of OSP was distributed at 27972 Da, OSP was composed of xylose, mannose, glucose, and galactose with the ratio of 2.9:6.6:166:2.6, with a trace amount of fucose, arabinose and rhamnose.	Mannose	102-109	claudin 11	Mus musculus	74-77
5773084-12	1969	It is believed that the more rapid utilization of mannose relative to glucose by intact hexokinase-deficient cells may be explained on the basis of the regulatory effect of the PMI reaction on the rate of mannose utilization.	Mannose	50-57	hexokinase 1	Homo sapiens	88-98
5773084-12	1969	It is believed that the more rapid utilization of mannose relative to glucose by intact hexokinase-deficient cells may be explained on the basis of the regulatory effect of the PMI reaction on the rate of mannose utilization.	Mannose	50-57	mannose phosphate isomerase	Homo sapiens	177-180
5690539-6	1968	Transferrin has most of its carbohydrate in a single unit composed of 2 residues of mannose, 2 residues of galactose, 3 residues of N-acetylglucosamine and either 1 or 2 residues of sialic acid.	Mannose	84-91	transferrin	Homo sapiens	0-11
14324543-0	1965	D-MANNOSE AS A CONSTITUENT OF THE DNA OF A MUTANT STRAIN OF BACTERIOPHAGE SP8.	Mannose	0-9	Sp8 transcription factor	Homo sapiens	74-77
5357018-7	1969	In ovalbumin glycopeptides with approximate mannose/hexosamine ratios 5:3 and 5:4, one and two N-acetylglucosamine residues respectively were accessible to the action of beta-N-acetylglucosaminidase.	Mannose	44-51	O-GlcNAcase	Homo sapiens	170-198
5357018-9	1969	A mixture of alpha-mannosidase and beta-N-acetylglucosaminidase, acting on an ovalbumin glycopeptide with mannose/hexosamine ratio 5:3.7, removed nearly 4moles of mannose and 1.5moles of N-acetylglucosamine.	Mannose	106-113	O-GlcNAcase	Homo sapiens	35-63
5357018-9	1969	A mixture of alpha-mannosidase and beta-N-acetylglucosaminidase, acting on an ovalbumin glycopeptide with mannose/hexosamine ratio 5:3.7, removed nearly 4moles of mannose and 1.5moles of N-acetylglucosamine.	Mannose	163-170	O-GlcNAcase	Homo sapiens	35-63
5357018-12	1969	The subsequent action of beta-N-acetylglucosaminidase liberated less than 1mole of N-acetylglucosamine and made at least 1mole further of mannose accessible to alpha-mannosidase action.	Mannose	138-145	O-GlcNAcase	Homo sapiens	25-53
5944237-7	1966	Glucokinase catalyses the phosphorylation of glucose, mannose and 2-deoxyglucose.	Mannose	54-61	glucokinase	Rattus norvegicus	0-11
33892066-8	2021	RESULTS: The average molecular weight of OSP was distributed at 27972 Da, OSP was composed of xylose, mannose, glucose, and galactose with the ratio of 2.9:6.6:166:2.6, with a trace amount of fucose, arabinose and rhamnose.	Mannose	102-109	claudin 11	Mus musculus	41-44
33986552-6	2021	We conclude that GMPPA acts as a cellular sensor to maintain mannose homeostasis through allosterically regulating GMPPB.	Mannose	61-68	GDP-mannose pyrophosphorylase Ab	Danio rerio	17-22
33900381-7	2021	Under basal conditions, FATP4/Fatp4 deficiency decreased the levels of ceramides and induced an upregulation of mannose receptor CD206 expression.	Mannose	112-119	solute carrier family 27 (fatty acid transporter), member 4	Mus musculus	24-29
33900381-7	2021	Under basal conditions, FATP4/Fatp4 deficiency decreased the levels of ceramides and induced an upregulation of mannose receptor CD206 expression.	Mannose	112-119	solute carrier family 27 (fatty acid transporter), member 4	Mus musculus	30-35
33900381-7	2021	Under basal conditions, FATP4/Fatp4 deficiency decreased the levels of ceramides and induced an upregulation of mannose receptor CD206 expression.	Mannose	112-119	mannose receptor C-type 1	Homo sapiens	129-134
33650863-5	2021	We found that isolation of UMOD resulted in a significant decrease in the relative quantity of high-mannose and sulfated glycans with a significant increase of neutral fucosylated glycans in the UMOD-depleted urine relative to the undepleted urine, but depletion had little impact on the sialylated glycans.	Mannose	100-107	uromodulin	Homo sapiens	27-31
33272761-3	2021	Patatin was an O-linked glycoprotein that contained fucose monosaccharides, as well as mannose, rhamnose, glucose, galactose, xylose, and arabinose.	Mannose	87-94	Patatin class I	Solanum tuberosum	0-7
33986552-6	2021	We conclude that GMPPA acts as a cellular sensor to maintain mannose homeostasis through allosterically regulating GMPPB.	Mannose	61-68	GDP-mannose pyrophosphorylase B	Danio rerio	115-120
33661628-1	2021	Oligomannoses are evolutionarily the oldest class of N-glycans, where the arms of the common pentasaccharide unit, i.e., Manalpha(1-6)-[Manalpha(1-3)]-Manbeta(1-4)-GlcNAcbeta(1-4)-GlcNAcbeta1-Asn, are functionalized exclusively with branched arrangements of mannose (Man) monosaccharide units.	Mannose	5-12	mannosidase alpha class 2C member 1	Homo sapiens	121-133
33734311-5	2021	We found that FUT8 could fucosylate most of high-mannose and complex-type N-glycans, including highly branched N-glycans from chicken ovalbumin, when the aglycone moiety is modified with a 9-fluorenylmethyloxycarbonyl (Fmoc) moiety or in a suitable peptide/protein context, even if they lack the terminal GlcNAc moiety on the Man-alpha1,3-Man arm.	Mannose	49-56	fucosyltransferase 8	Gallus gallus	14-18
33893702-3	2021	POMGNT2 is a glycosyltransferase which adds beta1,4-linked GlcNAc to the O-mannose (Man) residue to acquire core M3-type glycan.	Mannose	84-87	protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)	Homo sapiens	0-7
33893702-9	2021	Structure-based mutational studies confirmed that amino acid residues of the catalytic domain interacting with mannose or the TPT motif are essential for POMGNT2 enzymatic activity.	Mannose	111-118	protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)	Homo sapiens	154-161
33931731-5	2021	Using metabolomics coupled with FDG-PET imaging and seahorse analysis, we found that CCL5 participates in hippocampal fructose and mannose degradation, glycolysis, gluconeogenesis as well as glutamate and purine metabolism.	Mannose	131-138	chemokine (C-C motif) ligand 5	Mus musculus	85-89
34012659-11	2021	We also observed the increased ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3), which is trimming of N-linked glycans by sequential removal of mannose residues, might result in more non-N-glycosylated form of BST-2.	Mannose	161-168	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	31-88
34012659-11	2021	We also observed the increased ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3), which is trimming of N-linked glycans by sequential removal of mannose residues, might result in more non-N-glycosylated form of BST-2.	Mannose	161-168	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	90-95
34012659-11	2021	We also observed the increased ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3), which is trimming of N-linked glycans by sequential removal of mannose residues, might result in more non-N-glycosylated form of BST-2.	Mannose	161-168	bone marrow stromal cell antigen 2	Homo sapiens	227-232
33205491-4	2021	Results showed that RBP was found to contain 80.6% (w/w) of neutral sugars including D-fucose, D-mannose, D-glucose and D-galactose (1.7:1.4:1.0:1.8), and 12.5% (w/w) of proteins, which composed of glutamine, threonine, serine, etc.	Mannose	95-104	retinol binding protein 4, plasma	Mus musculus	20-23
33661628-1	2021	Oligomannoses are evolutionarily the oldest class of N-glycans, where the arms of the common pentasaccharide unit, i.e., Manalpha(1-6)-[Manalpha(1-3)]-Manbeta(1-4)-GlcNAcbeta(1-4)-GlcNAcbeta1-Asn, are functionalized exclusively with branched arrangements of mannose (Man) monosaccharide units.	Mannose	5-12	mannosidase alpha class 2C member 1	Homo sapiens	136-148
33661628-1	2021	Oligomannoses are evolutionarily the oldest class of N-glycans, where the arms of the common pentasaccharide unit, i.e., Manalpha(1-6)-[Manalpha(1-3)]-Manbeta(1-4)-GlcNAcbeta(1-4)-GlcNAcbeta1-Asn, are functionalized exclusively with branched arrangements of mannose (Man) monosaccharide units.	Mannose	5-12	mannosidase alpha class 2C member 1	Homo sapiens	151-162
33661628-1	2021	Oligomannoses are evolutionarily the oldest class of N-glycans, where the arms of the common pentasaccharide unit, i.e., Manalpha(1-6)-[Manalpha(1-3)]-Manbeta(1-4)-GlcNAcbeta(1-4)-GlcNAcbeta1-Asn, are functionalized exclusively with branched arrangements of mannose (Man) monosaccharide units.	Mannose	121-124	mannosidase alpha class 2C member 1	Homo sapiens	136-148
33661628-1	2021	Oligomannoses are evolutionarily the oldest class of N-glycans, where the arms of the common pentasaccharide unit, i.e., Manalpha(1-6)-[Manalpha(1-3)]-Manbeta(1-4)-GlcNAcbeta(1-4)-GlcNAcbeta1-Asn, are functionalized exclusively with branched arrangements of mannose (Man) monosaccharide units.	Mannose	121-124	mannosidase alpha class 2C member 1	Homo sapiens	151-162
33727664-7	2021	Analyses of structurally defined N-glycans from several yeast strains revealed that the mannose core is key to the upregulation of IL-10.	Mannose	88-95	interleukin 10	Mus musculus	131-136
33401221-0	2021	d-Mannose suppresses osteoarthritis development in vivo and delays IL-1beta-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.	Mannose	0-9	interleukin 1 alpha	Rattus norvegicus	67-75
33401221-0	2021	d-Mannose suppresses osteoarthritis development in vivo and delays IL-1beta-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.	Mannose	0-9	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	147-151
33401221-6	2021	In terms of a downstream mechanism, we showed that d-mannose might attenuate OA degeneration by activating autophagy in IL-1beta-treated rat chondrocytes by promoting the phosphorylation of 5" AMP-activated protein kinase (AMPK).	Mannose	51-60	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	223-227
33401221-7	2021	Our in vitro findings revealed that d-mannose delayed IL-1beta-induced OA degeneration in rat chondrocytes by enhancing autophagy activation through the AMPK pathway.	Mannose	36-45	interleukin 1 alpha	Rattus norvegicus	54-62
33401221-4	2021	We found that incubating interleukin (IL)-1beta-treated rat chondrocytes with d-mannose restrained OA degeneration by elevating cell proliferation, strongly activating autophagy, reducing apoptosis, and downregulating catabolism.	Mannose	78-87	interleukin 1 alpha	Rattus norvegicus	25-47
33401221-7	2021	Our in vitro findings revealed that d-mannose delayed IL-1beta-induced OA degeneration in rat chondrocytes by enhancing autophagy activation through the AMPK pathway.	Mannose	36-45	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	153-157
33401221-6	2021	In terms of a downstream mechanism, we showed that d-mannose might attenuate OA degeneration by activating autophagy in IL-1beta-treated rat chondrocytes by promoting the phosphorylation of 5" AMP-activated protein kinase (AMPK).	Mannose	51-60	interleukin 1 alpha	Rattus norvegicus	120-128
33401221-6	2021	In terms of a downstream mechanism, we showed that d-mannose might attenuate OA degeneration by activating autophagy in IL-1beta-treated rat chondrocytes by promoting the phosphorylation of 5" AMP-activated protein kinase (AMPK).	Mannose	51-60	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	193-221
32662414-9	2021	In addition, the mannose level (binding MNA-M and VVA mannose) was negatively correlated with C3 and complement 4 (C4) levels.	Mannose	17-24	complement C3	Homo sapiens	94-96
32662414-9	2021	In addition, the mannose level (binding MNA-M and VVA mannose) was negatively correlated with C3 and complement 4 (C4) levels.	Mannose	17-24	complement C4A (Rodgers blood group)	Homo sapiens	101-113
32662414-9	2021	In addition, the mannose level (binding MNA-M and VVA mannose) was negatively correlated with C3 and complement 4 (C4) levels.	Mannose	17-24	complement C4A (Rodgers blood group)	Homo sapiens	115-117
32662414-9	2021	In addition, the mannose level (binding MNA-M and VVA mannose) was negatively correlated with C3 and complement 4 (C4) levels.	Mannose	54-61	complement C3	Homo sapiens	94-96
32662414-9	2021	In addition, the mannose level (binding MNA-M and VVA mannose) was negatively correlated with C3 and complement 4 (C4) levels.	Mannose	54-61	complement C4A (Rodgers blood group)	Homo sapiens	101-113
32662414-9	2021	In addition, the mannose level (binding MNA-M and VVA mannose) was negatively correlated with C3 and complement 4 (C4) levels.	Mannose	54-61	complement C4A (Rodgers blood group)	Homo sapiens	115-117
33351779-5	2021	Anti-PLA2R1-IgG4 directly bound mannose-binding lectin in a glycosylation-dependent manner.	Mannose	32-39	phospholipase A2 receptor 1	Homo sapiens	5-11
33671632-9	2021	Hence, we demonstrate that EDEM3 provides a unique ERAD timing to misfolded glycoproteins, not only by its mannose trimming activity, but also by the positive and negative feedback modulated by the protease-associated and intrinsically disordered domain, respectively.	Mannose	107-114	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	27-32
33632285-1	2021	A recent report on long-term dietary mannose supplementation in phosphomannomutase 2 deficiency (PMM2-CDG) claimed improved glycosylation and called for double-blind randomized study of the dietary supplement in PMM2-CDG patients.	Mannose	37-44	phosphomannomutase 2	Homo sapiens	64-84
33632285-1	2021	A recent report on long-term dietary mannose supplementation in phosphomannomutase 2 deficiency (PMM2-CDG) claimed improved glycosylation and called for double-blind randomized study of the dietary supplement in PMM2-CDG patients.	Mannose	37-44	phosphomannomutase 2	Homo sapiens	97-101
33632285-1	2021	A recent report on long-term dietary mannose supplementation in phosphomannomutase 2 deficiency (PMM2-CDG) claimed improved glycosylation and called for double-blind randomized study of the dietary supplement in PMM2-CDG patients.	Mannose	37-44	phosphomannomutase 2	Homo sapiens	212-216
33632285-6	2021	We are concerned that renewed focus on mannose therapy in PMM2-CDG will detract from clinical trials of more promising therapies.	Mannose	39-46	phosphomannomutase 2	Homo sapiens	58-62
33545173-8	2021	In the Manalpha1-2Man complex, supplementary interactions with the reducing mannose residue explain the enhanced affinity for this disaccharide.	Mannose	76-83	mannosidase alpha class 2C member 1	Homo sapiens	7-16
33643289-2	2020	Two proteins with DM9 repeats have been recently identified from Pacific oyster Crassostrea gigas as mannose-specific binding pattern-recognition receptors (PRRs).	Mannose	101-108	Cyclic-AMP response element binding protein B	Drosophila melanogaster	18-21
33546740-3	2021	Ion chromatography (IC) revealed that THP contained glucose, arabinose, mannose, glucuronic acid, galactose and galacturonic acid, in different molar ratios.	Mannose	72-79	uromodulin	Mus musculus	38-41
33144549-5	2021	In addition, rMnn1477-935 was shown to mannosyl-phosphorylate high-mannose type N-glycans (Man7-9GlcNAc2) on recombinant human lysosomal alpha-glucosidase (rhGAA) with remarkably high efficiency.	Mannose	67-74	alpha glucosidase	Homo sapiens	127-154
32926407-9	2021	Osmotic controls L-glucose and D-mannose demonstrate that induction of IL-17A is a substance-independent, tonicity-dose-dependent process.	Mannose	31-40	interleukin 17A	Homo sapiens	71-77
33439436-7	2021	Furthermore, the glycoform analyses of N-glycans linked to 63 kDa and 54 kDa Ara h 1 subunits revealed that both typical high-mannose type and beta-xylosylated type N-glycans are linked to the molecules.	Mannose	126-133	allergen Ara h 1, clone P17	Arachis hypogaea	77-84
32787268-5	2021	Liposomes were surface-functionalized with a glut-1 targeting ligand mannose (MAN) and a cell-penetrating peptide (CPP) to enhance brain-targeting and cellular internalization, respectively.	Mannose	69-76	solute carrier family 2 (facilitated glucose transporter), member 1	Mus musculus	45-51
33525574-5	2021	Competitive BanLec-eGFP binding to high mannose glycans of the influenza vaccine (Vaxigrip ) was shown in a fluorescence-linked lectin sorbent assay (FLLSA) with monosaccharides (mannose and glucose) and wild type BanLec and H84T BanLec mutant.	Mannose	40-47	lectin	Musa acuminata	128-134
33513212-6	2021	The mannosylated extracellular domain of human DSG2 bound directly to the lectin domain of FimH in vitro, and introduction of a mutation in the FimH mannose-binding pocket abolished binding to DSG2.	Mannose	149-156	desmoglein 2	Homo sapiens	47-51
33513212-6	2021	The mannosylated extracellular domain of human DSG2 bound directly to the lectin domain of FimH in vitro, and introduction of a mutation in the FimH mannose-binding pocket abolished binding to DSG2.	Mannose	149-156	desmoglein 2	Homo sapiens	193-197
33537045-2	2020	The resulting high-mannose type (HMT)-FNGs, which carry one GlcNAc residue at the reducing end (GN1-FNGs), are ubiquitously found in developing plant cells.	Mannose	19-26	glycogenin 1	Homo sapiens	96-99
33584780-0	2021	Inactivation of N-Acetylglucosaminyltransferase I and alpha1,3-Fucosyltransferase Genes in Nicotiana tabacum BY-2 Cells Results in Glycoproteins With Highly Homogeneous, High-Mannose N-Glycans.	Mannose	175-182	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like	Nicotiana tabacum	16-49
33399442-4	2021	Here, we begin to test this hypothesis by comparing the effects of O-GlcNAc to other similar monosaccharides-glucose, N-acetyl-galactosamine (GalNAc), or mannose-on alpha-synuclein amyloid formation.	Mannose	154-161	synuclein alpha	Homo sapiens	165-180
32985191-0	2020	Chemical synthesis of ubiquitinated high-mannose type N-glycoprotein CCL1 in different folding states.	Mannose	41-48	C-C motif chemokine ligand 1	Homo sapiens	69-73
33444093-8	2021	beta2-GPI interacted with mannose-binding lectin in mouse plasma and ihBMEC medium, potentially involved in formation of thrombi.	Mannose	26-33	apolipoprotein H	Mus musculus	0-9
33840686-2	2021	C-type lectin receptors (CLRs), the representative PRRs, bind to microbial polysaccharides, among which Dectin-2 and Mincle recognize mannose-containing polysaccharides.	Mannose	134-141	C-type lectin domain family 4, member n	Mus musculus	104-112
33840686-2	2021	C-type lectin receptors (CLRs), the representative PRRs, bind to microbial polysaccharides, among which Dectin-2 and Mincle recognize mannose-containing polysaccharides.	Mannose	134-141	C-type lectin domain family 4, member e	Mus musculus	117-123
33010719-5	2021	Model antigen ovalbumin (OVA) was directly conjugated with mannose to obtain DCs targeting antigen, which was then complexed with polyethylenimine (PEI) through electrostatic interaction to form mannose-functionalized antigen nanoparticles (MAN-OVA/PEI NPs).	Mannose	59-66	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	14-23
33010719-5	2021	Model antigen ovalbumin (OVA) was directly conjugated with mannose to obtain DCs targeting antigen, which was then complexed with polyethylenimine (PEI) through electrostatic interaction to form mannose-functionalized antigen nanoparticles (MAN-OVA/PEI NPs).	Mannose	59-66	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	25-28
33010719-5	2021	Model antigen ovalbumin (OVA) was directly conjugated with mannose to obtain DCs targeting antigen, which was then complexed with polyethylenimine (PEI) through electrostatic interaction to form mannose-functionalized antigen nanoparticles (MAN-OVA/PEI NPs).	Mannose	195-202	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	14-23
33010719-5	2021	Model antigen ovalbumin (OVA) was directly conjugated with mannose to obtain DCs targeting antigen, which was then complexed with polyethylenimine (PEI) through electrostatic interaction to form mannose-functionalized antigen nanoparticles (MAN-OVA/PEI NPs).	Mannose	195-202	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	25-28
33379867-0	2021	Treatment of Rheumatoid Arthritis by Serum Albumin Nanoparticles Coated with Mannose to Target Neutrophils.	Mannose	77-84	albumin	Gallus gallus	37-50
33402096-6	2021	In vivo, D-mannose increased the frequency of Foxp3+ regulatory T cells in unmanipulated B6 mice.	Mannose	9-18	forkhead box P3	Mus musculus	46-51
33288007-4	2021	Recently, we showed that mannan in wheat (Triticum aestivum) grain endosperm has a linear structure of beta-1,4-linked mannose residues.	Mannose	119-126	a1	Triticum aestivum	103-109
33252732-5	2021	To-date, two families of GT-Cs involved in protein glycosylation have been structurally characterized: the family represented by PglB, AglB, and Stt3, which catalyzes oligosaccharide transfer to Asn, and the family represented by Pmt1 and Pmt2, which catalyzes mannose transfer to Thr or Ser.	Mannose	261-268	epiphycan	Homo sapiens	129-133
33375175-6	2020	While the neck/repeat region is involved in oligomeric dimerization, the CRD recognizes the mannose-containing structures present on specific glycoproteins such as those found on the SARS-CoV-2 spike protein.	Mannose	92-99	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	194-199
32985191-4	2020	CCL1 glycopeptide with a high-mannose-type N-glycan as well as a delta-thioLys residue was synthesized chemically.	Mannose	30-37	C-C motif chemokine ligand 1	Homo sapiens	0-4
32985191-2	2020	To demonstrate the accessibility toward a ubiquitinated glycoprotein probe for the study of glycoprotein degradation by UPS, we synthesized ubiquitinated glycoprotein CC motif chemokine 1 (CCL1) bearing a high-mannose type N-glycan, starting from six peptide segments.	Mannose	210-217	C-C motif chemokine ligand 1	Homo sapiens	189-193
32419574-8	2020	We conclude that the mannose-trimming activity of alpha1,2-mannosidase I coordinates the clustering and compartmentalization of CD147 that follows an epithelial injury.	Mannose	21-28	basigin (Ok blood group)	Homo sapiens	128-133
33391194-8	2020	Flow cytometry using the MLP and RSP cells, stained with calcofluor white, which specifically binds glucose/mannose units in beta (1   4) or beta (1   3) linkages, revealed the presence of lower content of polysaccharides containing such residues in the TCOL.	Mannose	108-115	immunoglobulin kappa variable 2D-18 (pseudogene)	Homo sapiens	125-152
33273096-6	2020	ECs that lack miR-223 showed a decrease of high mannose versus sialylated sugars on N-glycoproteins such as the metalloprotease Adam10.	Mannose	48-55	microRNA 223	Homo sapiens	14-21
33273096-6	2020	ECs that lack miR-223 showed a decrease of high mannose versus sialylated sugars on N-glycoproteins such as the metalloprotease Adam10.	Mannose	48-55	ADAM metallopeptidase domain 10	Homo sapiens	128-134
33315098-8	2022	CONCLUSIONS: In IgA nephropathy, the severity of the disease is associated with the level of IgA exposing N-Acetyl-D-Galactosamine, N-Acetyl-D-Glucosamine or mannose whereas C4d deposits are only associated with elevated levels of IgA1 glycoforms exhibiting glycan residues with specificity for mannose and N-Acetyl-D-Glucosamine binding lectins.	Mannose	158-165	immunoglobulin heavy variable 4-38-2-like	Homo sapiens	16-19
33315098-8	2022	CONCLUSIONS: In IgA nephropathy, the severity of the disease is associated with the level of IgA exposing N-Acetyl-D-Galactosamine, N-Acetyl-D-Glucosamine or mannose whereas C4d deposits are only associated with elevated levels of IgA1 glycoforms exhibiting glycan residues with specificity for mannose and N-Acetyl-D-Glucosamine binding lectins.	Mannose	295-302	immunoglobulin heavy variable 4-38-2-like	Homo sapiens	16-19
33315098-8	2022	CONCLUSIONS: In IgA nephropathy, the severity of the disease is associated with the level of IgA exposing N-Acetyl-D-Galactosamine, N-Acetyl-D-Glucosamine or mannose whereas C4d deposits are only associated with elevated levels of IgA1 glycoforms exhibiting glycan residues with specificity for mannose and N-Acetyl-D-Glucosamine binding lectins.	Mannose	295-302	immunoglobulin heavy variable 4-38-2-like	Homo sapiens	93-96
33311467-0	2020	D-mannose suppresses macrophage IL-1beta production.	Mannose	0-9	interleukin 1 alpha	Mus musculus	32-40
33311467-4	2020	Here, we show that D-mannose suppresses LPS-induced macrophage activation by impairing IL-1beta production.	Mannose	19-28	interleukin 1 alpha	Mus musculus	87-95
33311467-6	2020	Phosphomannose isomerase controls response of LPS-activated macrophages to D-mannose, which impairs glucose metabolism by raising intracellular mannose-6-phosphate levels.	Mannose	75-84	mannose phosphate isomerase	Mus musculus	0-24
33098580-1	2020	BACKGROUND: Mannose Phosphate Isomerase MPI-CDG (formerly CDG-1b) is a potentially fatal inherited metabolic disease which is readily treatable with oral D-mannose.	Mannose	154-163	mannose phosphate isomerase	Homo sapiens	58-64
33388127-3	2020	Herein, we provide a brief overview of the progress made on the development of synthetic carbohydrate-based epitope mimics for the elicitation of bnAbs directed to certain regions on Env gp120 protein: the outer domain high-mannose cluster and the variable loops V1V2 and V3.	Mannose	224-231	endogenous retrovirus group K member 20	Homo sapiens	183-186
33388127-3	2020	Herein, we provide a brief overview of the progress made on the development of synthetic carbohydrate-based epitope mimics for the elicitation of bnAbs directed to certain regions on Env gp120 protein: the outer domain high-mannose cluster and the variable loops V1V2 and V3.	Mannose	224-231	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	187-192
33328457-4	2020	In this report, we biochemically identified a CCAAT-box transcription factor (SlNFYA10) that can bind to the promoter of SlGME1, which encodes GDP-Man-3",5"-epimerase, a pivotal enzyme in the D-mannose/L-galactose pathway.	Mannose	192-201	GDP-mannose 3',5'-epimerase	Solanum lycopersicum	121-127
33328457-5	2020	Importantly, SlNFYA10 simultaneously binds to the promoter of SlGGP1, a downstream gene of SlGME1 in the D-mannose/L-galactose pathway.	Mannose	105-114	GDP-mannose 3',5'-epimerase	Solanum lycopersicum	91-97
32853832-2	2020	We used the optimized mannose-functionalized dendrimeric nanoparticle (mDNP)-based platform for macrophage-specific delivery of therapeutics to simultaneously deliver SR-A siRNA (to reduce LDL uptake) and LXR ligand (LXR-L, to stimulate cholesterol efflux) - a novel "Two-pronged" approach to facilitate plaque regression.	Mannose	22-29	macrophage scavenger receptor 1	Mus musculus	167-171
33447557-2	2020	Methods: The PAP was prepared from an inactivated P. aeruginosa-mannose sensitive hemagglutinin (PA-MSHA) strain, a genetically engineered heat-inactivated PA strain with, mannose-sensitive binding activity, which can induce tumor cell apoptosis.	Mannose	64-71	poly(A) polymerase alpha	Homo sapiens	13-16
33447557-2	2020	Methods: The PAP was prepared from an inactivated P. aeruginosa-mannose sensitive hemagglutinin (PA-MSHA) strain, a genetically engineered heat-inactivated PA strain with, mannose-sensitive binding activity, which can induce tumor cell apoptosis.	Mannose	172-179	poly(A) polymerase alpha	Homo sapiens	13-16
33151749-8	2021	It can be concluded that the improvement in obesity complications including insulin resistance in obese adolescent boys after CRT may be due to decrease in plasma levels of mannose and BCAAs and increase urinary metabolites.	Mannose	173-180	insulin	Homo sapiens	76-83
33098580-9	2020	Poor compliance with D-mannose was correlated with recurrence of diarrhea, thrombosis, and abnormal biological parameters including coagulation factors and transferrin profiles.	Mannose	21-30	transferrin	Homo sapiens	156-167
32810478-13	2020	An increase in STT3B activity was associated to the generation of mannose-rich N-glycans.	Mannose	66-73	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)	Mus musculus	15-20
32948893-6	2020	We demonstrate that all three sugar kinases initially affect Mig1 nuclear localization upon addition of glucose, fructose and mannose.	Mannose	126-133	transcription factor MIG1	Saccharomyces cerevisiae S288C	61-65
32948893-7	2020	This initial import of Mig1 into the nucleus was temporary; for continuous nucleocytoplasmic shuttling of Mig1, Hxk2 is required in the presence of glucose and mannose and in the presence of fructose Hxk2 or Hxk1 is required.	Mannose	160-167	transcription factor MIG1	Saccharomyces cerevisiae S288C	23-27
32948893-7	2020	This initial import of Mig1 into the nucleus was temporary; for continuous nucleocytoplasmic shuttling of Mig1, Hxk2 is required in the presence of glucose and mannose and in the presence of fructose Hxk2 or Hxk1 is required.	Mannose	160-167	hexokinase 2	Saccharomyces cerevisiae S288C	112-116
32975514-3	2020	Here, we show that Protein O-Mannose Kinase (POMK), which phosphorylates mannose of core M3 (GalNAc-beta1,3-GlcNAc-beta1,4-Man) preceding matriglycan synthesis, is required for LARGE1-mediated generation of full-length matriglycan on alpha-DG (~150 kDa).	Mannose	73-80	protein-O-mannose kinase	Mus musculus	19-43
33046650-8	2020	Also, the mannan-binding lectin (MBL2), an innate immune lectin that negatively impacts influenza outcomes, recognizes influenza virus-infected cells in a high mannose-dependent manner.	Mannose	160-167	mannose binding lectin 2	Homo sapiens	10-31
33046650-8	2020	Also, the mannan-binding lectin (MBL2), an innate immune lectin that negatively impacts influenza outcomes, recognizes influenza virus-infected cells in a high mannose-dependent manner.	Mannose	160-167	mannose binding lectin 2	Homo sapiens	33-37
32504713-3	2020	In this study, a polysaccharide from the Rhizoma of Atractylodis macrocephala Koidz., designated as RAMP2, with an absolute molecular weight of 4.354 x 103 Da was isolated and found to be composed of mannose, galacturonic acid, glucose, galactose and arabinose.	Mannose	200-207	receptor (calcitonin) activity modifying protein 2	Mus musculus	100-105
33048944-7	2020	In the present study, we designed a probe using Polyamidoamine (PAMAM) fifth-generation (G5) dendrimers conjugated with mannose, Cyanine 7 (Cy7), and hydrazinonicotinamide (HYNIC) for target macrophages with high expression of MRC1 in the tumor.	Mannose	120-127	mannose receptor C-type 1	Homo sapiens	227-231
33048944-9	2020	Our results show that high-density mannose dendrimers are preferentially bound by macrophages treated by IFNgamma and LPS that express lower levels of MRC1 than for macrophages treated by IL-4 that express high levels of MRC1.	Mannose	35-42	interferon gamma	Homo sapiens	105-113
33048944-9	2020	Our results show that high-density mannose dendrimers are preferentially bound by macrophages treated by IFNgamma and LPS that express lower levels of MRC1 than for macrophages treated by IL-4 that express high levels of MRC1.	Mannose	35-42	mannose receptor C-type 1	Homo sapiens	151-155
33048944-9	2020	Our results show that high-density mannose dendrimers are preferentially bound by macrophages treated by IFNgamma and LPS that express lower levels of MRC1 than for macrophages treated by IL-4 that express high levels of MRC1.	Mannose	35-42	interleukin 4	Homo sapiens	188-192
33048944-9	2020	Our results show that high-density mannose dendrimers are preferentially bound by macrophages treated by IFNgamma and LPS that express lower levels of MRC1 than for macrophages treated by IL-4 that express high levels of MRC1.	Mannose	35-42	mannose receptor C-type 1	Homo sapiens	221-225
32590192-7	2020	A dual-targeting delivery liposomal system was designed with dual-modification of PD-L1 nanobody and mannose ligands for co-delivering an mTOR inhibitor (rapamycin) and an anti-angiogenic drug (regorafenib).	Mannose	101-108	mechanistic target of rapamycin kinase	Homo sapiens	138-142
32700756-6	2020	The effects of mannose on the PI3K/AKT and ERK signalling pathways were explored through western blot analysis assessing the expression of phosphorylated (p)-AKT and p-ERK1/2.	Mannose	15-22	AKT serine/threonine kinase 1	Homo sapiens	35-38
32700756-6	2020	The effects of mannose on the PI3K/AKT and ERK signalling pathways were explored through western blot analysis assessing the expression of phosphorylated (p)-AKT and p-ERK1/2.	Mannose	15-22	mitogen-activated protein kinase 1	Homo sapiens	43-46
32975514-3	2020	Here, we show that Protein O-Mannose Kinase (POMK), which phosphorylates mannose of core M3 (GalNAc-beta1,3-GlcNAc-beta1,4-Man) preceding matriglycan synthesis, is required for LARGE1-mediated generation of full-length matriglycan on alpha-DG (~150 kDa).	Mannose	73-80	protein-O-mannose kinase	Mus musculus	45-49
32975514-3	2020	Here, we show that Protein O-Mannose Kinase (POMK), which phosphorylates mannose of core M3 (GalNAc-beta1,3-GlcNAc-beta1,4-Man) preceding matriglycan synthesis, is required for LARGE1-mediated generation of full-length matriglycan on alpha-DG (~150 kDa).	Mannose	73-80	LARGE xylosyl- and glucuronyltransferase 1	Mus musculus	177-183
32450234-15	2020	PCP1.1, PCP1.2 and PCP2.1 were composed of fucose, arabinose, galactose, glucose, mannose, galacturonic acid and glucuronic acid; and PCP2.2 was composed of arabinose, galactose, glucose, galacturonic acid and glucuronic acid.	Mannose	82-89	Purkinje cell protein 2	Homo sapiens	19-23
33003435-5	2020	Silencing MAN1A1 also makes cells softer, suggesting that an increase of high mannose N-glycoforms may change the physical properties of the cell membrane.	Mannose	78-85	mannosidase alpha class 1A member 1	Homo sapiens	10-16
32962735-0	2020	Dietary mannose supplementation in phosphomannomutase 2 deficiency (PMM2-CDG).	Mannose	8-15	phosphomannomutase 2	Homo sapiens	35-55
32962735-0	2020	Dietary mannose supplementation in phosphomannomutase 2 deficiency (PMM2-CDG).	Mannose	8-15	phosphomannomutase 2	Homo sapiens	68-72
32962735-2	2020	While supplying mannose to PMM2-deficient fibroblasts corrects the altered N-glycosylation in vitro, short term therapeutic approaches with mannose supplementation in PMM2-CDG patients have been unsuccessful.	Mannose	16-23	phosphomannomutase 2	Homo sapiens	27-31
32962735-4	2020	This retrospective study analyzes the first long term mannose supplementation in 20 PMM2-CDG patients.	Mannose	54-61	phosphomannomutase 2	Homo sapiens	84-88
32962735-9	2020	A double-blind randomized study is needed to examine the role of mannose in the design of a therapy for children with PMM2-CDG in more detail.	Mannose	65-72	phosphomannomutase 2	Homo sapiens	118-122
32686492-5	2022	The glycosyl residues of ICP-1 were composed of (1 ), (1 4) and (1 6) glucose, (1 5) arabinose, (1 4) galacturonic acid and (1 3,6) mannose.	Mannose	132-139	ATPase phospholipid transporting 8B1	Homo sapiens	25-30
32806600-4	2020	Deploying biochemical-silencing methods and molecular interaction studies in HBV-expressing liver cells, we herein identified the cellular ERGIC-53, a high-mannose-specific lectin, and distinct components of the endoplasmic reticulum (ER) export machinery COPII as crucial factors of viral trafficking and egress.	Mannose	156-163	lectin, mannose binding 1	Homo sapiens	139-147
31785297-3	2020	Galactose (33.47%), beta-d-Glucose (26.71%) and alpha-d-Mannose (18.21%) were the major monosaccharides components presenting in PAP, and a smaller amounts of beta-d-Galactose, d-Fructose, alpha-d-Glucose, alpha-l-Galactose and arabinose were detected.	Mannose	48-63	poly (A) polymerase beta (testis specific)	Mus musculus	129-132
32786531-7	2020	The binding activities of the obtained multi-arm glycopolymers with mannose-specific human lectins, DC-SIGN and MBL, were investigated via surface plasmon resonance spectroscopy.	Mannose	68-75	mannose-binding lectin family member 3, pseudogene	Homo sapiens	112-115
32786538-4	2020	Cu-mediated reversible deactivation radical polymerization (Cu-RDRP) technique was employed for the synthesis of mannose containing star-shaped glycopolymers with varying arm number and length.	Mannose	113-120	steroidogenic acute regulatory protein	Homo sapiens	132-136
32981293-5	2020	For example, increased plasma mannose levels due to decreased uptake in the liver have been identified as a potential biomarker of early insulin resistance by multi-omics approaches.	Mannose	30-37	insulin	Homo sapiens	137-144
32729597-1	2020	High-mannose (Man9GlcNAc2) is the main carbohydrate unit present in viral envelope glycoproteins such as gp120 of HIV and the GP1 of Ebola virus.	Mannose	5-12	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	105-110
32729597-1	2020	High-mannose (Man9GlcNAc2) is the main carbohydrate unit present in viral envelope glycoproteins such as gp120 of HIV and the GP1 of Ebola virus.	Mannose	5-12	GTP binding protein 1	Homo sapiens	126-129
32729597-4	2020	Herein, we report the synthesis of the Man9 epitope with both alpha and beta configurations at the reducing end, and subsequent evaluation of the impact of this configuration on binding to natural receptor of high-mannose, DC-SIGN.	Mannose	214-221	mannosidase alpha class 1A member 1	Homo sapiens	39-43
32824208-3	2020	M2-type macrophages overexpress the mannose receptor CD206.	Mannose	36-43	mannose receptor, C type 1	Mus musculus	53-58
32409323-1	2020	OBJECTIVES: FBXO6, a component of the ubiquitin E3 ligases, has been shown to bind high mannose N-linked glycoproteins and act as ubiquitin ligase subunits.	Mannose	88-95	F-box protein 6	Mus musculus	12-17
32484235-3	2020	Whole genome re-sequencing revealed a mutation in ALG12 (Asparagine-Linked Glycosylation 12) that encodes the mannosyltransferase responsible for adding the eighth mannose residue in an alpha-1,6 linkage to the dolichol-PP-oligosaccharide N-glycosylation glycan tree precursors.	Mannose	164-171	homolog of asparagine-linked glycosylation 12	Arabidopsis thaliana	50-55
32484235-3	2020	Whole genome re-sequencing revealed a mutation in ALG12 (Asparagine-Linked Glycosylation 12) that encodes the mannosyltransferase responsible for adding the eighth mannose residue in an alpha-1,6 linkage to the dolichol-PP-oligosaccharide N-glycosylation glycan tree precursors.	Mannose	164-171	homolog of asparagine-linked glycosylation 12	Arabidopsis thaliana	57-91
32171755-4	2020	Previous data from our lab has shown that endothelial inflammation produces multiple N-glycoforms of ICAM-1, and that a hypoglycosylated, or high-mannose (HM), form of ICAM-1 enhances adhesion of pro-inflammatory monocytes associated with more severe atherosclerosis and adverse cardiac events.	Mannose	146-153	intercellular adhesion molecule 1	Homo sapiens	168-174
32027983-5	2020	However, the extracellular domain (ECD) of M6PR is highly complex, containing 15-mannose receptor homology (MRH) domains.	Mannose	81-88	mannose-6-phosphate receptor, cation dependent	Homo sapiens	43-47
31822129-6	2020	The procedure was also successfully tried on hydrophilic tetra- and hexa-peptides of Ribonuclease B carrying an N-glycosylation site occupied with "high-mannose" N-glycan chains.	Mannose	153-160	hexosaminidase subunit alpha	Homo sapiens	68-72
32470085-7	2020	The other cell line, C1s-/- MGAT1- CHOK1 1.A1, contains a deletion in both the C1s gene and the MGAT1 gene, which limits glycosylation to mannose-5 or earlier intermediates in the N-linked glycosylation pathway.	Mannose	138-145	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Cricetulus griseus	96-101
31958555-6	2020	LCP-1 had a molecular weight of 2.303 x 105 Da and 7.519 x 103 Da, and was composed of mannose (Man), ribose (Rib), rhamnose (Rha), glucuronic acid (GluA), galacturonic acid (GalA), glucose (Glu), galactose (Gal), xylose (Xyl), arabinose (Ara) and fucuronic (Fuc).	Mannose	87-94	lymphocyte cytosolic protein 1	Mus musculus	0-5
31855290-2	2020	Tumour-associated macrophages, expressing the haemoglobin-haptoglobin and mannose receptors CD163 and CD206, are crucial for cancer progression.	Mannose	74-81	CD163 molecule	Homo sapiens	92-97
31855290-2	2020	Tumour-associated macrophages, expressing the haemoglobin-haptoglobin and mannose receptors CD163 and CD206, are crucial for cancer progression.	Mannose	74-81	mannose receptor C-type 1	Homo sapiens	102-107
32363175-6	2020	When we applied this method to the glycoproteomic analysis of glycoengineered Chinese hamster ovary (CHO)-K1 cells with alpha1,6-fucosyltransferase (FUT8) knockout, the results showed that the knockout of FUT8 altered the overall glycosylation profile of CHO-K1 cells with the elimination of core fucosylation and together with increases in high-mannose and sialylated N-glycans.	Mannose	346-353	alpha-(1,6)-fucosyltransferase	Cricetulus griseus	120-147
32363175-6	2020	When we applied this method to the glycoproteomic analysis of glycoengineered Chinese hamster ovary (CHO)-K1 cells with alpha1,6-fucosyltransferase (FUT8) knockout, the results showed that the knockout of FUT8 altered the overall glycosylation profile of CHO-K1 cells with the elimination of core fucosylation and together with increases in high-mannose and sialylated N-glycans.	Mannose	346-353	alpha-(1,6)-fucosyltransferase	Cricetulus griseus	149-153
32272076-5	2020	Moreover, the extensive array of oligomannose glycans on Env shields peptidic B cell epitopes, impedes the presentation of T helper cell epitopes, and attracts mannose binding proteins, which could affect the antibody response.	Mannose	38-45	endogenous retrovirus group K member 20	Homo sapiens	57-60
32308412-0	2020	Mannose Suppresses the Proliferation and Metastasis of Lung Cancer by Targeting the ERK/GSK-3beta/beta-Catenin/SNAIL Axis.	Mannose	0-7	mitogen-activated protein kinase 1	Homo sapiens	84-87
32308412-0	2020	Mannose Suppresses the Proliferation and Metastasis of Lung Cancer by Targeting the ERK/GSK-3beta/beta-Catenin/SNAIL Axis.	Mannose	0-7	glycogen synthase kinase 3 alpha	Homo sapiens	88-97
32308412-0	2020	Mannose Suppresses the Proliferation and Metastasis of Lung Cancer by Targeting the ERK/GSK-3beta/beta-Catenin/SNAIL Axis.	Mannose	0-7	catenin beta 1	Homo sapiens	98-110
32308412-0	2020	Mannose Suppresses the Proliferation and Metastasis of Lung Cancer by Targeting the ERK/GSK-3beta/beta-Catenin/SNAIL Axis.	Mannose	0-7	snail family transcriptional repressor 1	Homo sapiens	111-116
32308412-3	2020	Methods: Here, we performed ex vivo experiments and established a nude mouse model to evaluate the anticancer effects of mannose on NSCLC cells and its effects on the ERK/GSK-3beta/beta-catenin/SNAIL axis.	Mannose	121-128	mitogen-activated protein kinase 1	Mus musculus	167-170
32308412-3	2020	Methods: Here, we performed ex vivo experiments and established a nude mouse model to evaluate the anticancer effects of mannose on NSCLC cells and its effects on the ERK/GSK-3beta/beta-catenin/SNAIL axis.	Mannose	121-128	glycogen synthase kinase 3 alpha	Mus musculus	171-180
32308412-3	2020	Methods: Here, we performed ex vivo experiments and established a nude mouse model to evaluate the anticancer effects of mannose on NSCLC cells and its effects on the ERK/GSK-3beta/beta-catenin/SNAIL axis.	Mannose	121-128	catenin (cadherin associated protein), beta 1	Mus musculus	181-193
32308412-3	2020	Methods: Here, we performed ex vivo experiments and established a nude mouse model to evaluate the anticancer effects of mannose on NSCLC cells and its effects on the ERK/GSK-3beta/beta-catenin/SNAIL axis.	Mannose	121-128	snail family zinc finger 1	Mus musculus	194-199
32308412-6	2020	qRT-PCR was used to evaluate the effects of mannose on the mRNA expression of beta-catenin.	Mannose	44-51	catenin beta 1	Homo sapiens	78-90
32308412-7	2020	Western blotting was conducted to explore the effects of mannose on the ERK/GSK-3beta/beta-catenin/SNAIL axis and nuclear accumulation of beta-catenin.	Mannose	57-64	mitogen-activated protein kinase 1	Homo sapiens	72-75
32308412-7	2020	Western blotting was conducted to explore the effects of mannose on the ERK/GSK-3beta/beta-catenin/SNAIL axis and nuclear accumulation of beta-catenin.	Mannose	57-64	glycogen synthase kinase 3 alpha	Homo sapiens	76-85
32308412-7	2020	Western blotting was conducted to explore the effects of mannose on the ERK/GSK-3beta/beta-catenin/SNAIL axis and nuclear accumulation of beta-catenin.	Mannose	57-64	catenin beta 1	Homo sapiens	86-98
32308412-7	2020	Western blotting was conducted to explore the effects of mannose on the ERK/GSK-3beta/beta-catenin/SNAIL axis and nuclear accumulation of beta-catenin.	Mannose	57-64	snail family transcriptional repressor 1	Homo sapiens	99-104
32308412-12	2020	Using Western blotting, we observed that mannose reduced SNAIL and beta-catenin expression and ERK activation and promoted phospho-GSK-3beta expression.	Mannose	41-48	snail family transcriptional repressor 1	Homo sapiens	57-62
32308412-12	2020	Using Western blotting, we observed that mannose reduced SNAIL and beta-catenin expression and ERK activation and promoted phospho-GSK-3beta expression.	Mannose	41-48	catenin beta 1	Homo sapiens	67-79
32308412-12	2020	Using Western blotting, we observed that mannose reduced SNAIL and beta-catenin expression and ERK activation and promoted phospho-GSK-3beta expression.	Mannose	41-48	mitogen-activated protein kinase 1	Homo sapiens	95-98
32308412-12	2020	Using Western blotting, we observed that mannose reduced SNAIL and beta-catenin expression and ERK activation and promoted phospho-GSK-3beta expression.	Mannose	41-48	glycogen synthase kinase 3 alpha	Homo sapiens	131-140
32308412-13	2020	The ERK agonist LM22B-10 promoted the metastatic ability of NSCLC cells and increased SNAIL and beta-catenin expression in cancer cells, which could be reversed by mannose.	Mannose	164-171	mitogen-activated protein kinase 1	Homo sapiens	4-7
32693897-23	2020	RT-qPCR result showed that 150 mug/mL mannose increased the expression level of GLUT4(P<0.	Mannose	38-45	solute carrier family 2 (facilitated glucose transporter), member 4	Mus musculus	80-85
32693897-29	2020	CONCLUSION: Mannose and inositol can improve the expression of GLUT4 mRNA, which may help to increase glucose uptake by peripheral cells.	Mannose	12-19	solute carrier family 2 (facilitated glucose transporter), member 4	Mus musculus	63-68
32102878-5	2020	The extraordinarily high concentration of the monosaccharide fructose in semen contributes significantly to the effect by competitively inhibiting binding of ligands to alpha1,2-linked mannose residues on Env.	Mannose	185-192	endogenous retrovirus group W member 1, envelope	Homo sapiens	205-208
32213588-6	2020	Exclusive elucidation of differentially expressed membrane glycoproteins and molecular modeling suggested that extended high-mannose glycosylation at the helical domain of transferrin receptor protein 1 promotes conformational changes that improve noncovalent interaction energies and lead to enhancement of cell migration in metastatic cholangiocarcinoma.	Mannose	125-132	transferrin receptor	Homo sapiens	172-202
31917981-2	2020	SHP-1 was mainly composed of galacturonic acid, galactose, rhamnose and arabinose (molar ratio = 46.59%:17.95%:14.77%:13.97%) with small amounts of fucose, glucose, mannose and xylose.	Mannose	165-172	nuclear receptor subfamily 0 group B member 2	Homo sapiens	0-5
31958555-7	2020	The molecular weight of LCP-2 was 2.655 x 105 Da, and its monosaccharide constituents were Man, Rib, Rha, GluA, Glu, Gal, Xyl, Ara and Fuc.	Mannose	91-94	lymphocyte cytosolic protein 2	Mus musculus	24-29
32308412-13	2020	The ERK agonist LM22B-10 promoted the metastatic ability of NSCLC cells and increased SNAIL and beta-catenin expression in cancer cells, which could be reversed by mannose.	Mannose	164-171	snail family transcriptional repressor 1	Homo sapiens	86-91
32308412-13	2020	The ERK agonist LM22B-10 promoted the metastatic ability of NSCLC cells and increased SNAIL and beta-catenin expression in cancer cells, which could be reversed by mannose.	Mannose	164-171	catenin beta 1	Homo sapiens	96-108
31958555-6	2020	LCP-1 had a molecular weight of 2.303 x 105 Da and 7.519 x 103 Da, and was composed of mannose (Man), ribose (Rib), rhamnose (Rha), glucuronic acid (GluA), galacturonic acid (GalA), glucose (Glu), galactose (Gal), xylose (Xyl), arabinose (Ara) and fucuronic (Fuc).	Mannose	96-99	lymphocyte cytosolic protein 1	Mus musculus	0-5
32308412-16	2020	Furthermore, mannose inhibited ERK/GSK-3beta/beta-catenin/SNAIL in tumour tissues obtained from nude mice.	Mannose	13-20	mitogen-activated protein kinase 1	Mus musculus	31-34
32308412-16	2020	Furthermore, mannose inhibited ERK/GSK-3beta/beta-catenin/SNAIL in tumour tissues obtained from nude mice.	Mannose	13-20	glycogen synthase kinase 3 alpha	Mus musculus	35-44
32208424-3	2020	However, our recent studies suggest that hypoglycosylated or high mannose (HM)-ICAM-1 N-glycoforms are also expressed on the cell surface during endothelial dysfunction, and have higher affinity for monocyte adhesion and regulate outside-in endothelial signaling by different mechanisms.	Mannose	66-73	intercellular adhesion molecule 1	Homo sapiens	79-85
32308412-16	2020	Furthermore, mannose inhibited ERK/GSK-3beta/beta-catenin/SNAIL in tumour tissues obtained from nude mice.	Mannose	13-20	catenin (cadherin associated protein), beta 1	Mus musculus	45-57
32308412-16	2020	Furthermore, mannose inhibited ERK/GSK-3beta/beta-catenin/SNAIL in tumour tissues obtained from nude mice.	Mannose	13-20	snail family zinc finger 1	Mus musculus	58-63
32308412-17	2020	Discussion: Collectively, these findings suggest that mannose exerts anti-metastatic activity against NSCLC by inhibiting the activation of the ERK/GSK-3beta/beta-catenin/SNAIL axis, which indicates the potential anticancer effects of mannose.	Mannose	54-61	mitogen-activated protein kinase 1	Mus musculus	144-147
32308412-17	2020	Discussion: Collectively, these findings suggest that mannose exerts anti-metastatic activity against NSCLC by inhibiting the activation of the ERK/GSK-3beta/beta-catenin/SNAIL axis, which indicates the potential anticancer effects of mannose.	Mannose	54-61	glycogen synthase kinase 3 alpha	Mus musculus	148-157
32308412-17	2020	Discussion: Collectively, these findings suggest that mannose exerts anti-metastatic activity against NSCLC by inhibiting the activation of the ERK/GSK-3beta/beta-catenin/SNAIL axis, which indicates the potential anticancer effects of mannose.	Mannose	54-61	catenin (cadherin associated protein), beta 1	Mus musculus	158-170
32308412-17	2020	Discussion: Collectively, these findings suggest that mannose exerts anti-metastatic activity against NSCLC by inhibiting the activation of the ERK/GSK-3beta/beta-catenin/SNAIL axis, which indicates the potential anticancer effects of mannose.	Mannose	54-61	snail family zinc finger 1	Mus musculus	171-176
32308412-17	2020	Discussion: Collectively, these findings suggest that mannose exerts anti-metastatic activity against NSCLC by inhibiting the activation of the ERK/GSK-3beta/beta-catenin/SNAIL axis, which indicates the potential anticancer effects of mannose.	Mannose	235-242	mitogen-activated protein kinase 1	Mus musculus	144-147
32273875-0	2020	Removal of Mannose-Ending Glycan at Asn2118 Abrogates FVIII Presentation by Human Monocyte-Derived Dendritic Cells.	Mannose	11-18	coagulation factor VIII	Homo sapiens	54-59
32273875-3	2020	Here, we investigated whether altering the interaction of factor VIII with mannose-sensitive receptors on antigen-presenting cells may be a strategy to reduce factor VIII immunogenicity.	Mannose	75-82	coagulation factor VIII	Mus musculus	58-69
32273875-3	2020	Here, we investigated whether altering the interaction of factor VIII with mannose-sensitive receptors on antigen-presenting cells may be a strategy to reduce factor VIII immunogenicity.	Mannose	75-82	coagulation factor VIII	Mus musculus	159-170
32273875-9	2020	Further investigations in preclinical models of hemophilia A closer to humans are needed to decipher the exact role of mannose-ending glycans in factor VIII immunogenicity.	Mannose	119-126	coagulation factor VIII	Mus musculus	145-156
32075990-0	2020	Author Correction: Macrophage Mannose Receptor CD206 Predicts Prognosis in Community-acquired Pneumonia.	Mannose	30-37	mannose receptor C-type 1	Homo sapiens	47-52
32109354-1	2020	The high mannose patch (HMP) of the HIV envelope protein (Env) is the structure most frequently targeted by broadly neutralizing antibodies; therefore, many researchers have attempted to use mimics of this region as a vaccine immunogen.	Mannose	9-16	endogenous retrovirus group K member 6, envelope	Homo sapiens	40-56
32109354-1	2020	The high mannose patch (HMP) of the HIV envelope protein (Env) is the structure most frequently targeted by broadly neutralizing antibodies; therefore, many researchers have attempted to use mimics of this region as a vaccine immunogen.	Mannose	9-16	endogenous retrovirus group K member 6, envelope	Homo sapiens	58-61
32119644-6	2020	Silencing MR or deleting mannose residues on Env rescues Env expression in HIV-1-infected macrophages lacking Vpr.	Mannose	25-32	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	45-48
32119644-6	2020	Silencing MR or deleting mannose residues on Env rescues Env expression in HIV-1-infected macrophages lacking Vpr.	Mannose	25-32	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	57-60
32119644-8	2020	Together these results reveal a Vpr-Nef-Env axis that hijacks a host mannose-MR response system to facilitate infection while evading MR"s normal role, which is to trap and destroy mannose-expressing pathogens.	Mannose	69-76	Vpr	Human immunodeficiency virus 1	32-35
32119644-8	2020	Together these results reveal a Vpr-Nef-Env axis that hijacks a host mannose-MR response system to facilitate infection while evading MR"s normal role, which is to trap and destroy mannose-expressing pathogens.	Mannose	69-76	S100 calcium binding protein B	Homo sapiens	36-39
32119644-8	2020	Together these results reveal a Vpr-Nef-Env axis that hijacks a host mannose-MR response system to facilitate infection while evading MR"s normal role, which is to trap and destroy mannose-expressing pathogens.	Mannose	69-76	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	40-43
32119644-8	2020	Together these results reveal a Vpr-Nef-Env axis that hijacks a host mannose-MR response system to facilitate infection while evading MR"s normal role, which is to trap and destroy mannose-expressing pathogens.	Mannose	181-188	Vpr	Human immunodeficiency virus 1	32-35
32119644-8	2020	Together these results reveal a Vpr-Nef-Env axis that hijacks a host mannose-MR response system to facilitate infection while evading MR"s normal role, which is to trap and destroy mannose-expressing pathogens.	Mannose	181-188	S100 calcium binding protein B	Homo sapiens	36-39
32119644-8	2020	Together these results reveal a Vpr-Nef-Env axis that hijacks a host mannose-MR response system to facilitate infection while evading MR"s normal role, which is to trap and destroy mannose-expressing pathogens.	Mannose	181-188	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	40-43
31302751-5	2020	AQP2-L137P was predominantly detected as a high-mannose form of AQP2, whereas AQP2-WT was observed in both non-glycosylated and complex glycosylated forms.	Mannose	48-55	aquaporin 2	Homo sapiens	0-5
31302751-5	2020	AQP2-L137P was predominantly detected as a high-mannose form of AQP2, whereas AQP2-WT was observed in both non-glycosylated and complex glycosylated forms.	Mannose	48-55	aquaporin 2	Homo sapiens	0-4
31825135-7	2020	Functionally, high CD206 enhances mannose-dependent endocytosis and uptake of type-I collagen.	Mannose	34-41	mannose receptor C-type 1	Homo sapiens	19-24
32060313-3	2020	EndoBT-3987 is a key endo-beta-N-acetylglucosaminidase (ENGase) that initiates the degradation/processing of mammalian high-mannose-type (HM-type) N-glycans in the intestine.	Mannose	124-131	O-GlcNAcase	Homo sapiens	26-54
32065582-0	2020	EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD.	Mannose	61-68	ER degradation enhancing alpha-mannosidase like protein 2	Homo sapiens	0-5
32065582-0	2020	EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD.	Mannose	61-68	thioredoxin domain containing 11	Homo sapiens	33-40
31826991-4	2020	Since the presence of head region high mannose glycosites dictates SP-D activity, the ability to predict these glycosite glycan subtypes may be of value.	Mannose	39-46	surfactant protein D	Homo sapiens	67-71
31826991-13	2020	Lung surfactant protein D (SP-D), a key factor in first line innate immunity defence, removes IAV through interaction with hemagglutinin (HA) head region high mannose glycan(s).	Mannose	159-166	surfactant protein D	Homo sapiens	0-25
31826991-13	2020	Lung surfactant protein D (SP-D), a key factor in first line innate immunity defence, removes IAV through interaction with hemagglutinin (HA) head region high mannose glycan(s).	Mannose	159-166	surfactant protein D	Homo sapiens	27-31
32060313-3	2020	EndoBT-3987 is a key endo-beta-N-acetylglucosaminidase (ENGase) that initiates the degradation/processing of mammalian high-mannose-type (HM-type) N-glycans in the intestine.	Mannose	124-131	endo-beta-N-acetylglucosaminidase	Homo sapiens	56-62
32152943-1	2020	CLEC5A is a spleen tyrosine kinase (Syk)-coupled C-type lectin that is highly expressed by monocytes, macrophages, neutrophils, and dendritic cells and interacts with virions directly, via terminal fucose and mannose moieties of viral glycans.	Mannose	209-216	C-type lectin domain containing 5A	Homo sapiens	0-6
31913607-4	2020	The low PMI (mannose 6-phosphate isomerase) level of both osteosarcoma cell lines comparing to normal human osteoblasts is the reason of abnormal metabolic pathway of two osteosarcoma cell lines with mannose treatment.	Mannose	13-20	mannose phosphate isomerase	Homo sapiens	8-11
31823246-10	2020	Molecular modelling of glycopeptide 1 and GpalphaDG1 scFv suggested that their interaction occurs through hydrogen bonds and hydrophobic contacts involving amino acids from scFv (I51, Y33, S229, Y235, and P233) and R8 and alpha-mannose from Glycopeptide 1.	Mannose	228-235	immunglobulin heavy chain variable region	Homo sapiens	53-57
31657484-0	2020	Mannose-capped lipoarabinomannan-induced B10 cells decrease severity of dextran sodium sulfate-induced inflammatory bowel disease in mice.	Mannose	0-7	granzyme C	Mus musculus	41-44
31657484-4	2020	We have recently reported that B10 cells can be induced by ManLAM (mannose-capped lipoarabinomannan), a major cell-wall lipoglycan of M.tb (Mycobacterium tuberculosis).	Mannose	67-74	granzyme C	Mus musculus	31-34
31726133-4	2020	A structural analysis showed that the monosaccharides of EPS H31-2 included d-mannose (Man) and d-glucose (Glc).	Mannose	76-85	H3 clustered histone 3	Homo sapiens	61-64
31901900-3	2020	Using biochemical assays, computer-aided docking/molecular dynamics simulations, and fluorescence microscopy, we found that RSV can operate as a direct inhibitor of glyco-PD-L1-processing enzymes (alpha-glucosidase/alpha-mannosidase) that modulate N-linked glycan decoration of PD-L1, thereby promoting the endoplasmic reticulum retention of a mannose-rich, abnormally glycosylated form of PD-L1.	Mannose	344-351	sucrase-isomaltase	Homo sapiens	197-214
31162802-0	2020	Combined deficiency of factors V and VIII in a Chinese family due to a novel nonsense mutation in lectin mannose binding protein 1.	Mannose	105-112	cytochrome c oxidase subunit 8A	Homo sapiens	37-41
31565801-1	2020	A series of broadly neutralizing antibodies called PGT have been shown to be bound directly to human immunodeficiency virus type-1 via high mannose glycans on glycoprotein gp120.	Mannose	140-147	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	172-177
32152943-1	2020	CLEC5A is a spleen tyrosine kinase (Syk)-coupled C-type lectin that is highly expressed by monocytes, macrophages, neutrophils, and dendritic cells and interacts with virions directly, via terminal fucose and mannose moieties of viral glycans.	Mannose	209-216	spleen associated tyrosine kinase	Homo sapiens	36-39
32342808-7	2020	RESULTS: The study results showed that mannose, methyl stearate, and three unknown metabolites, increased in GSTM1 positive patients; and glycolic acid, porphine, monomethyl phosphate, fumaric acid, and three others unknown metabolites, decreased in GSTM1 positive patients.	Mannose	39-46	glutathione S-transferase mu 1	Homo sapiens	109-114
32741939-3	2020	Because some TLR9-positive immune cells express mannose receptors (MR), the uptake of polypodna by immune cells can be further increased by its modification with mannose.	Mannose	48-55	toll-like receptor 9	Mus musculus	13-17
32741939-3	2020	Because some TLR9-positive immune cells express mannose receptors (MR), the uptake of polypodna by immune cells can be further increased by its modification with mannose.	Mannose	162-169	toll-like receptor 9	Mus musculus	13-17
31766009-1	2020	Mannose Receptor (MR) and DC-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) are two mannose-specific targets for antigens carried by liposomes but DC-SIGN is more specific of DCs.	Mannose	112-119	mannose receptor C-type 1	Homo sapiens	0-16
32306323-4	2020	To analyze the function of EDEM proteins, we expressed and purified recombinant EDEM3 from HEK293 cells and assessed its mannose-trimming activity in vitro.	Mannose	121-128	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	80-85
31682799-0	2020	Mannose is an insulin-regulated metabolite reflecting whole-body insulin sensitivity in man.	Mannose	0-7	insulin	Homo sapiens	14-21
31682799-0	2020	Mannose is an insulin-regulated metabolite reflecting whole-body insulin sensitivity in man.	Mannose	0-7	insulin	Homo sapiens	65-72
31682799-4	2020	However, potential direct effects of mannose on insulin sensitivity in vivo or in vitro are unknown.	Mannose	37-44	insulin	Homo sapiens	48-55
31682799-7	2020	These data suggest that mannose is a marker, and not a mediator, of insulin resistance.	Mannose	24-31	insulin	Homo sapiens	68-75
31682799-9	2020	Mannose was reduced by insulin infusion in proportion to whole-body insulin sensitivity.	Mannose	0-7	insulin	Homo sapiens	23-30
31682799-9	2020	Mannose was reduced by insulin infusion in proportion to whole-body insulin sensitivity.	Mannose	0-7	insulin	Homo sapiens	68-75
31682799-10	2020	Thus, mannose is a biomarker of insulin resistance which may be useful for the early identification of diabetic individuals with insulin resistance and increased risk of its complications.	Mannose	6-13	insulin	Homo sapiens	32-39
31682799-10	2020	Thus, mannose is a biomarker of insulin resistance which may be useful for the early identification of diabetic individuals with insulin resistance and increased risk of its complications.	Mannose	6-13	insulin	Homo sapiens	129-136
32812835-6	2020	While either the presence of complex biantennary or high mannose afucosylated glycoforms significantly increased FcgammaRIIIa binding activity compared to fucosylated glycoforms, they did not similarly increase aggregated Abeta uptake activity mediated by different effector cells.	Mannose	57-64	Fc gamma receptor IIIa	Homo sapiens	113-125
32306330-3	2020	Although Fbs proteins recognize innermost Man3GlcNAc2 structure that is commonly found in most N-glycan structures, they preferentially bind high-mannose-type glycans.	Mannose	146-153	F-box protein 8	Homo sapiens	9-12
32306341-1	2020	ZG16p is a soluble 16-kDa protein abundantly expressed in the pancreas and gut, and has a beta-prism fold structure similar to that of mannose-binding Jacalin-related lectins (mJRLs) such as BanLec, Heltuba, and Artocarpin.	Mannose	135-142	zymogen granule protein 16	Rattus norvegicus	0-5
32306341-2	2020	ZG16p binds to mannose via the well-conserved GXXXD loop among mJRLs and sulfated glycosaminoglycans (e.g., heparin and heparan sulfate) via the basic patch of molecular surface.	Mannose	15-22	zymogen granule protein 16	Rattus norvegicus	0-5
31831667-1	2019	Oligosaccharyltransferase (OST) catalyzes the transfer of a high-mannose glycan onto secretory proteins in the endoplasmic reticulum.	Mannose	65-72	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	0-25
31921220-7	2019	Preclinical investigation of the mechanisms underlying the success of IL-10 gene therapy revealed the unexpected discovery of the powerful anti-nociceptive anti-inflammatory properties of D-mannose, an adjuvant in the non-viral gene therapeutic formulation.	Mannose	188-197	interleukin 10	Homo sapiens	70-75
31756283-7	2019	The presence of the PPO-GP on the surface of the scaffold was tested monitoring the interaction of an analogous mannose containing PPO-GP scaffold and the mannose binding lectin Con-A.	Mannose	155-162	protoporphyrinogen oxidase	Homo sapiens	20-23
31756283-7	2019	The presence of the PPO-GP on the surface of the scaffold was tested monitoring the interaction of an analogous mannose containing PPO-GP scaffold and the mannose binding lectin Con-A.	Mannose	155-162	protoporphyrinogen oxidase	Homo sapiens	131-134
31831667-1	2019	Oligosaccharyltransferase (OST) catalyzes the transfer of a high-mannose glycan onto secretory proteins in the endoplasmic reticulum.	Mannose	65-72	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	27-30
31842258-3	2019	Toward producing a more cost-effective and safe alternative to the commercial mammalian cell-based production systems, we have produced recombinant human IDUA in seeds of an Arabidopsis mutant to generate the enzyme in a biologically active and non-immunogenic form containing predominantly high mannose N-linked glycans.	Mannose	296-303	alpha-L-iduronidase	Homo sapiens	154-158
31738061-0	2019	Chemoenzymatic Synthesis of O-Mannose Glycans Containing Sulfated or Non-Sulfated HNK-1 Epitope.	Mannose	28-37	beta-1,3-glucuronyltransferase 1	Homo sapiens	82-87
31915415-3	2019	Mannan (or mannose)-binding lectin (MBL), a soluble C-type lectin, is traditionally recognized as an initiator of the complement pathway.	Mannose	11-18	mannose binding lectin 2	Homo sapiens	36-39
31842258-8	2019	Although the in planta M6P-tagging process efficiency would need to be improved, an exciting outcome of our work was that the plant-derived mannose-terminated IDUA yielded results comparable to those obtained with the commercial IDUA (Aldurazyme  (Sanofi, Paris, France)), and a significant amount of the plant-IDUA is trafficked by a M6P receptor-independent pathway.	Mannose	140-147	alpha-L-iduronidase	Homo sapiens	159-163
31842258-8	2019	Although the in planta M6P-tagging process efficiency would need to be improved, an exciting outcome of our work was that the plant-derived mannose-terminated IDUA yielded results comparable to those obtained with the commercial IDUA (Aldurazyme  (Sanofi, Paris, France)), and a significant amount of the plant-IDUA is trafficked by a M6P receptor-independent pathway.	Mannose	140-147	alpha-L-iduronidase	Homo sapiens	229-233
31842258-8	2019	Although the in planta M6P-tagging process efficiency would need to be improved, an exciting outcome of our work was that the plant-derived mannose-terminated IDUA yielded results comparable to those obtained with the commercial IDUA (Aldurazyme  (Sanofi, Paris, France)), and a significant amount of the plant-IDUA is trafficked by a M6P receptor-independent pathway.	Mannose	140-147	alpha-L-iduronidase	Homo sapiens	229-233
31817246-5	2019	We demonstrated that mannose-containing glycans increased on glycoproteins in aged mouse brains and identified synapsin-1 as one major carrier of paucimannose in aged brains.	Mannose	21-28	synapsin I	Mus musculus	111-121
31007088-10	2019	In addition, mannose in the structure of MLCMNP improved IL-6, TNF-alpha and IFN-gamma (&gt;16 fold) cytokines genes expression by macrophage/dendritic cells after exposure in 12 h. Immunization of experimental mice (subcutaneously, two times with 2-week intervals) with 5 microg of HBsAg loaded on MLCMNP nanoparticles increased specific total IgG and IgG2a/IgG1 ratio.	Mannose	13-20	interleukin 6	Homo sapiens	57-61
31007088-10	2019	In addition, mannose in the structure of MLCMNP improved IL-6, TNF-alpha and IFN-gamma (&gt;16 fold) cytokines genes expression by macrophage/dendritic cells after exposure in 12 h. Immunization of experimental mice (subcutaneously, two times with 2-week intervals) with 5 microg of HBsAg loaded on MLCMNP nanoparticles increased specific total IgG and IgG2a/IgG1 ratio.	Mannose	13-20	tumor necrosis factor	Homo sapiens	63-72
31007088-10	2019	In addition, mannose in the structure of MLCMNP improved IL-6, TNF-alpha and IFN-gamma (&gt;16 fold) cytokines genes expression by macrophage/dendritic cells after exposure in 12 h. Immunization of experimental mice (subcutaneously, two times with 2-week intervals) with 5 microg of HBsAg loaded on MLCMNP nanoparticles increased specific total IgG and IgG2a/IgG1 ratio.	Mannose	13-20	interferon gamma	Homo sapiens	77-86
31007088-10	2019	In addition, mannose in the structure of MLCMNP improved IL-6, TNF-alpha and IFN-gamma (&gt;16 fold) cytokines genes expression by macrophage/dendritic cells after exposure in 12 h. Immunization of experimental mice (subcutaneously, two times with 2-week intervals) with 5 microg of HBsAg loaded on MLCMNP nanoparticles increased specific total IgG and IgG2a/IgG1 ratio.	Mannose	13-20	immunoglobulin heavy variable V1-9	Mus musculus	353-358
31007088-10	2019	In addition, mannose in the structure of MLCMNP improved IL-6, TNF-alpha and IFN-gamma (&gt;16 fold) cytokines genes expression by macrophage/dendritic cells after exposure in 12 h. Immunization of experimental mice (subcutaneously, two times with 2-week intervals) with 5 microg of HBsAg loaded on MLCMNP nanoparticles increased specific total IgG and IgG2a/IgG1 ratio.	Mannose	13-20	immunoglobulin heavy constant gamma 1 (G1m marker)	Mus musculus	359-363
31299190-2	2019	Mannose-binding lectin/ficolin-associated protein (MAp44), a multifunctional complement regulator, regulates the complement activation by competing with MASP-1, MASP-2 and MASP-3 for MBL and ficolin binding sites.	Mannose	0-7	LOW QUALITY PROTEIN: mannan-binding lectin serine protease 1	Oreochromis niloticus	153-159
31382820-6	2019	QPS1, with a molecular weight of 34.0 kDa, was mainly composed of mannose, rhamnose, galacturonic acid, glucose, galactose, xylose and arabinose at a molar ratio of 2.63:2.40:1.64:6.28:1.95:2.48:5.01.	Mannose	66-73	succinate dehydrogenase complex, subunit C, integral membrane protein	Mus musculus	0-4
31299190-2	2019	Mannose-binding lectin/ficolin-associated protein (MAp44), a multifunctional complement regulator, regulates the complement activation by competing with MASP-1, MASP-2 and MASP-3 for MBL and ficolin binding sites.	Mannose	0-7	mannan-binding lectin serine protease 2	Oreochromis niloticus	161-167
31016744-2	2019	A rare, monogenic disorder in which children with mutations in mannose phosphate isomerase (MPI) develop liver fibrosis led us to explore the function of MPI and mannose metabolism in liver development and adult liver diseases.	Mannose	63-70	mannose phosphate isomerase	Homo sapiens	92-95
31529350-3	2019	ALG12-CDG is due to deficiency of ALG12 alpha1,6-mannosyltransferase that adds the eighth mannose residue on the dolichol-PP-oligosaccharide precursor in the endoplasmic reticulum.	Mannose	90-97	ALG12 alpha-1,6-mannosyltransferase	Homo sapiens	0-5
31395617-5	2019	RESULTS: Two patients in the clinically defined cohort had rare loss-of-function variants in ALG9, which encodes a protein required for addition of specific mannose molecules to the assembling N-glycan precursors in the endoplasmic reticulum lumen.	Mannose	157-164	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	93-97
31529350-3	2019	ALG12-CDG is due to deficiency of ALG12 alpha1,6-mannosyltransferase that adds the eighth mannose residue on the dolichol-PP-oligosaccharide precursor in the endoplasmic reticulum.	Mannose	90-97	ALG12 alpha-1,6-mannosyltransferase	Homo sapiens	34-68
31659013-2	2019	A subset of mannose receptor (CD206)-expressing monocyte-derived DCs was found in skin, and their migratory counterpart is present in skin-draining lymph nodes (sdLNs).	Mannose	12-19	mannose receptor, C type 1	Mus musculus	30-35
31244409-3	2019	The chemical structural analysis revealed that BFP mainly consisted of galactose together with a small amount of uronic acid, mannose, and glucose.	Mannose	126-133	ring finger protein 112	Homo sapiens	47-50
31777307-2	2019	Mannose (Man) was found to bind better to CD206 receptors on the surface of tumor-associated macrophages (TAMs), thereby increasing the number of nano-dandelion engulfed by TAMs.	Mannose	0-7	mannose receptor C-type 1	Homo sapiens	42-47
31533545-7	2019	FLT3 is initially synthesized as a 110 KD protein, which glycosylated in the endoplasmic reticulum to a 130 KD immature protein rich in mannose, and further processed into a mature 160 KD protein in the Golgi apparatus, which could be transferred to the cell surface.	Mannose	136-143	fms related receptor tyrosine kinase 3	Homo sapiens	0-4
31748021-7	2019	Herein, we observed that how anti-cardiac troponin I (cTnI) antibody (Ab) conjugated with the linker, polyethylene glycol (PEG), on the surface of liposomes influenced the affinity of mannose derivatives with transporter and regulated distribution of these vesicles in the heart and brain.	Mannose	184-191	troponin I3, cardiac type	Homo sapiens	54-58
31469191-1	2019	Chemical modification of pseudo-dimannoside ligands guided by fragment-based design allowed to exploit an ammonium-binding region in the vicinity of the mannose-binding site of DC-SIGN, leading to the synthesis of a glycomimetic antagonist (compound 16) of unprecedented affinity and selectivity against the related lectin langerin.	Mannose	153-160	CD207 molecule	Homo sapiens	323-331
31398058-0	2019	High-mannose intercellular adhesion molecule-1 (ICAM-1) enhances CD16+ monocyte adhesion to the endothelium.	Mannose	5-12	intercellular adhesion molecule 1	Homo sapiens	13-46
31398058-0	2019	High-mannose intercellular adhesion molecule-1 (ICAM-1) enhances CD16+ monocyte adhesion to the endothelium.	Mannose	5-12	intercellular adhesion molecule 1	Homo sapiens	48-54
31398058-0	2019	High-mannose intercellular adhesion molecule-1 (ICAM-1) enhances CD16+ monocyte adhesion to the endothelium.	Mannose	5-12	Fc gamma receptor IIIa	Homo sapiens	65-69
31398058-4	2019	Here, we tested the hypothesis that a high mannose (HM) N-glycoform of intercellular adhesion molecule-1 (ICAM-1) on the endothelium mediates the selective recruitment of CD16+ monocytes.	Mannose	43-50	intercellular adhesion molecule 1	Homo sapiens	71-104
31398058-4	2019	Here, we tested the hypothesis that a high mannose (HM) N-glycoform of intercellular adhesion molecule-1 (ICAM-1) on the endothelium mediates the selective recruitment of CD16+ monocytes.	Mannose	43-50	intercellular adhesion molecule 1	Homo sapiens	106-112
31398058-4	2019	Here, we tested the hypothesis that a high mannose (HM) N-glycoform of intercellular adhesion molecule-1 (ICAM-1) on the endothelium mediates the selective recruitment of CD16+ monocytes.	Mannose	43-50	Fc gamma receptor IIIa	Homo sapiens	171-175
31426994-2	2019	Monosaccharide composition analysis indicated that SLP-4 was composed of mannose, rhamnose, galacturonic acid, glucose, galactose, xylose and arabinose in a molar ratio of 0.825:2.030:14.998:0.841:8.260:4.039:6.009.	Mannose	73-80	sphingosine-1-phosphate receptor 4	Homo sapiens	51-56
31446139-0	2019	Association between -221 X/Y polymorphism of mannose-binding lectin (MBL) gene and susceptibility to HTLV-1 infection among people from an endemic region in the Northeast of Iran.	Mannose	45-52	mannose binding lectin 2	Homo sapiens	69-72
31593795-2	2019	We synthesized and manufactured a mannose-modified poly (beta-amino ester) (PBAE) nano-vaccines with easily tuneable and pH-sensitive characteristics to co-deliver the tumour-associated antigen polypeptide Trp-2 and the TLR4 agonist monophosphoryl lipid A (MPLA).	Mannose	34-41	tRNA-Pro (anticodon AGG) 2-6	Homo sapiens	206-211
31495937-1	2019	Bovine alpha-lactalbumin (BLA) was treated by ultrasonic at 150 W/cm2 for different times and subsequently glycated with mannose by dry-heating.	Mannose	121-128	lactalbumin alpha	Bos taurus	7-24
31593795-2	2019	We synthesized and manufactured a mannose-modified poly (beta-amino ester) (PBAE) nano-vaccines with easily tuneable and pH-sensitive characteristics to co-deliver the tumour-associated antigen polypeptide Trp-2 and the TLR4 agonist monophosphoryl lipid A (MPLA).	Mannose	34-41	toll like receptor 4	Homo sapiens	220-224
31401282-2	2019	Physicochemical characterization showed that PSP-1 with the average molecular weight of 1.036 x 106 Da was composed of fucose, arabinose, galactose, glucose, xylose, mannose, galacturonic acid and glucuronic acid in a molar ratio of 18.45:2.15:19.06:1.89:16.07:1.00:5.74:20.09.	Mannose	166-173	paraspeckle component 1	Homo sapiens	45-50
31640729-0	2019	Unsuccessful intravenous D-mannose treatment in PMM2-CDG.	Mannose	25-34	phosphomannomutase 2	Homo sapiens	48-52
31640729-3	2019	RESULTS: We report on a boy with a severe PMM2-CDG who received a continuous intravenous mannose infusion over a period of 5 months during the first year of life in a dose of 0.8 g/kg/day.	Mannose	89-96	phosphomannomutase 2	Homo sapiens	42-46
31376448-4	2019	AGC1 (average molecular weight: 5.2kDa) was predominantly composed of galactose (>60%) along with the presence of several other neutral sugars such as arabinose, xylose, glucose, mannose and rhamnose in minor amounts.	Mannose	179-186	aggrecan	Mus musculus	0-4
31637232-3	2019	One of these PPRs, DC-SIGN, a member of the C-type lectin receptor (CLR) family, has been extensively targeted with Lewis structures and mannose glycans, often presented in multivalent fashion.	Mannose	137-144	C-type lectin domain family 4 member D	Homo sapiens	44-66
31614968-8	2019	The results demonstrated that the structure of MOS5 is a beta-(1,4)-mannotetraose with alpha-(1,6)-galactose attached at the second mannose unit from non-reducing end.	Mannose	132-139	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	57-66
31488546-3	2019	Solid-phase binding competition assays, glycoprotein blotting experiments and glycan array analysis employing the lectin-like domains of cow and mouse CD23 demonstrate that they bind to mannose, N-acetylglucosamine, glucose, and fucose and to glycoproteins that bear these sugars in nonreducing terminal positions.	Mannose	186-193	Fc receptor, IgE, low affinity II, alpha polypeptide	Mus musculus	151-155
31637232-3	2019	One of these PPRs, DC-SIGN, a member of the C-type lectin receptor (CLR) family, has been extensively targeted with Lewis structures and mannose glycans, often presented in multivalent fashion.	Mannose	137-144	C-type lectin domain family 4 member D	Homo sapiens	68-71
31466401-5	2019	High-mannose glycans are the natural ligands of dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), a dendritic cell associated C-type lectin receptor (CLR), which has the ability to efficiently internalize its cargo and direct it to both major histocompatibility complex (MHC)-I and MHC-II pathways for the induction of CD8+ and CD4+ T cell responses, respectively.	Mannose	5-12	CD209 molecule	Homo sapiens	48-127
31073667-2	2019	In this study, we examined orf19.5244 in the genome database of the pathogenic fungus Candida albicans, a homologue of the Saccharomyces cerevisiae mannose-ethanolamine phosphotransferase gene, MCD4, which plays a role in GPI synthesis.	Mannose	148-155	mannose-ethanolamine phosphotransferase MCD4	Saccharomyces cerevisiae S288C	194-198
31286209-2	2019	We evaluated whether a polymorphism in the mannose-binding lectin (MBL) gene at codon 54 influences the occurrence of fallopian tube blockage in relation to exposure to Chlamydia trachomatis.	Mannose	43-50	mannose binding lectin 2	Homo sapiens	67-70
31180129-9	2019	Chicken mucin monosaccharides included l-fucose (Fuc), d-mannose (Man), d-galactose (Gal), N-acetyl-d-galactosamine (GalNAc), N-acetyl-d-glucosamine (GlcNAc), and Neu5Ac (sialic acid).	Mannose	55-64	mucin 2, oligomeric mucus/gel-forming	Gallus gallus	8-13
31399515-3	2019	Mannose-binding lectin-associated serine proteases (MASPs) are key enzymes of the lectin pathway, and MASP-1 and/or MASP-3 are reported to be involved in the activation of FD.	Mannose	0-7	mannan-binding lectin serine peptidase 1	Mus musculus	102-108
30264323-1	2019	Truncated 4"-thionucleosides 1-4 and 4"-oxonucleosides 5-8 as potent and selective A3AR antagonists were synthesized from D-mannose and D-erythronic acid gamma-lactone, respectively.	Mannose	122-131	adenosine A3 receptor	Mus musculus	83-87
31158404-2	2019	This BSP faction was consisted of mannose and glucose at a molar ratio of 2.4:1 approximately, with a molecular weight of 146 KDa.	Mannose	34-41	integrin binding sialoprotein	Homo sapiens	5-8
31308178-5	2019	We provide evidence that cell surface-associated VEGFR2 displays sialylated N-glycans at Asn-247 and, in contrast, that the nearby sites Asn-145 and Asn-160 contain lower levels of sialylated N-glycans and higher levels of high-mannose N-glycans, respectively.	Mannose	228-235	kinase insert domain receptor	Homo sapiens	49-55
31466401-5	2019	High-mannose glycans are the natural ligands of dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), a dendritic cell associated C-type lectin receptor (CLR), which has the ability to efficiently internalize its cargo and direct it to both major histocompatibility complex (MHC)-I and MHC-II pathways for the induction of CD8+ and CD4+ T cell responses, respectively.	Mannose	5-12	CD209 molecule	Homo sapiens	129-136
31466401-5	2019	High-mannose glycans are the natural ligands of dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), a dendritic cell associated C-type lectin receptor (CLR), which has the ability to efficiently internalize its cargo and direct it to both major histocompatibility complex (MHC)-I and MHC-II pathways for the induction of CD8+ and CD4+ T cell responses, respectively.	Mannose	5-12	C-type lectin domain family 4 member D	Homo sapiens	167-189
31466401-5	2019	High-mannose glycans are the natural ligands of dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), a dendritic cell associated C-type lectin receptor (CLR), which has the ability to efficiently internalize its cargo and direct it to both major histocompatibility complex (MHC)-I and MHC-II pathways for the induction of CD8+ and CD4+ T cell responses, respectively.	Mannose	5-12	C-type lectin domain family 4 member D	Homo sapiens	191-194
31466401-5	2019	High-mannose glycans are the natural ligands of dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), a dendritic cell associated C-type lectin receptor (CLR), which has the ability to efficiently internalize its cargo and direct it to both major histocompatibility complex (MHC)-I and MHC-II pathways for the induction of CD8+ and CD4+ T cell responses, respectively.	Mannose	5-12	CD8a molecule	Homo sapiens	360-363
31466401-5	2019	High-mannose glycans are the natural ligands of dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), a dendritic cell associated C-type lectin receptor (CLR), which has the ability to efficiently internalize its cargo and direct it to both major histocompatibility complex (MHC)-I and MHC-II pathways for the induction of CD8+ and CD4+ T cell responses, respectively.	Mannose	5-12	CD4 molecule	Homo sapiens	369-372
31141293-4	2019	However, the EXOs with mannose-conjugated PEG-DSPE (EXO-PEG-man) exhibit excellent intracellular uptake into the DCs and boost the immune response by the incorporation of adjuvant, monophosphoryl lipid A (MPLA) within the EXO.	Mannose	23-30	5'-3' exoribonuclease 1	Mus musculus	13-16
31485527-9	2019	The time of UV irradiation gives the longer energy for the bond formation between the positive C atoms of the carbonyl group and the O atoms of the hydroxyl group at C-6 atoms of mannose and galactose.	Mannose	179-186	complement C6	Homo sapiens	166-169
31412567-4	2019	The four purified polysaccharides (Pe1, Pe2, Pe3, Pe4) from TCBL are mainly composed of arabinose, galactose, glucose, a small amount of xylose, and mannose.	Mannose	149-156	ETS variant transcription factor 3	Homo sapiens	35-38
31123037-8	2019	Gene-metabolite networks revealed a positive association between the hepatic glycan synthesis gene alpha-1,6-mannosyltransferase (Alg12) mRNA and mannose, which are important for protein glycosylation.	Mannose	146-153	asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)	Mus musculus	130-135
30986453-3	2019	CAP-3, an acidic polysaccharide with a molecular weight of 121.34 kDa, was separated and purified from CAPs, which was only composed of glucose and mannose.	Mannose	148-155	serine (or cysteine) peptidase inhibitor, clade B, member 9	Mus musculus	0-5
30936012-5	2019	SP1-1 (4.56 x 105 Da) was mainly composed of mannose, ribose, glucuronic acid, glucose, xylose and arabinose with molar ratios of 2.14:3.61:1:2.86:5.98:36.39.	Mannose	45-52	trans-acting transcription factor 1	Mus musculus	0-5
31353707-5	2019	The results indicated that DIP-1 was consisted of mannose, glucosamine, glucose, galactose and arabinose in a ratio of 1.00:0.42:18.36:14.17:0.81, and its molecular weight was 218.3 kDa.	Mannose	50-57	cyclin D1 binding protein 1	Homo sapiens	27-32
31256876-3	2019	We describe ten unrelated families with bi-allelic mutations in PIGB, a gene that encodes phosphatidylinositol glycan class B, which transfers the third mannose to the GPI.	Mannose	153-160	phosphatidylinositol glycan anchor biosynthesis class B	Homo sapiens	64-68
31136099-6	2019	Postproteomic site-specific N-glycan analyses showed that human complement C3 bears high-mannose and hybrid glycoforms rather than complex glycoforms at Asn85.	Mannose	89-96	complement C3	Homo sapiens	64-77
31136099-7	2019	The abundance of complement C3 with mannose-5 or mannose-6 glycoform at Asn85 was associated with HCC tumor grade.	Mannose	36-43	complement C3	Homo sapiens	17-30
31136099-7	2019	The abundance of complement C3 with mannose-5 or mannose-6 glycoform at Asn85 was associated with HCC tumor grade.	Mannose	49-56	complement C3	Homo sapiens	17-30
31141293-4	2019	However, the EXOs with mannose-conjugated PEG-DSPE (EXO-PEG-man) exhibit excellent intracellular uptake into the DCs and boost the immune response by the incorporation of adjuvant, monophosphoryl lipid A (MPLA) within the EXO.	Mannose	23-30	5'-3' exoribonuclease 1	Mus musculus	52-55
31141731-3	2019	Mannose as primary ligand for the mannose-binding lectin (MBL) activates the lectin pathway of complement.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	34-56
31141731-3	2019	Mannose as primary ligand for the mannose-binding lectin (MBL) activates the lectin pathway of complement.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	58-61
30926436-3	2019	UPP-2 mainly consisted of xylose (64.55%), glucose (23.81%), arabinose (5.90%) and mannose (4.26%), and its main glycosidic linkage types included  2)-alpha-D-Xylp-(1 ,  4)-alpha-D-Glcp-(1 , alpha-D-Xylp-(1  and  2,4)-beta-D-Xylp-(1   .	Mannose	83-90	uridine phosphorylase 2	Mus musculus	0-5
30925286-3	2019	Here we fabricated mannose-functionalized lipid-hybrid polymersomes (MAN-IMO-PS) for co-delivery of ovalbumin antigen both inside the inner core and outside the lipid layer, TLR7/8 agonist imiquimod within the hydrophobic membrane, TLR4 agonist monophosphoryl lipid A in the lipid layer as programmed nanovaccine to synergistically activate immune responses for improving vaccine efficacy.	Mannose	19-26	toll like receptor 7	Homo sapiens	174-178
30925286-3	2019	Here we fabricated mannose-functionalized lipid-hybrid polymersomes (MAN-IMO-PS) for co-delivery of ovalbumin antigen both inside the inner core and outside the lipid layer, TLR7/8 agonist imiquimod within the hydrophobic membrane, TLR4 agonist monophosphoryl lipid A in the lipid layer as programmed nanovaccine to synergistically activate immune responses for improving vaccine efficacy.	Mannose	19-26	toll like receptor 4	Homo sapiens	232-236
30879666-2	2019	LPD2 was composed of arabinose, mannose, glucose, and galactose in a molar ratio of 0.25:0.49:1:0.5 with average molecular weight of 9.64 x 106 Da.	Mannose	32-39	neuroguidin	Homo sapiens	0-4
30737517-1	2019	Branching and processing of N-glycans in the medial-Golgi rely both on the transport of the donor UDP-N-acetylglucosamine (UDP-GlcNAc) to the Golgi lumen by the SLC35A3 nucleotide sugar transporter (NST) as well as on the addition of the GlcNAc residue to terminal mannoses in nascent N-glycans by several linkage-specific N-acetyl-glucosaminyltransferases (MGAT1-MGAT5).	Mannose	265-273	solute carrier family 35 member A3	Homo sapiens	161-168
31060014-1	2019	OBJECTIVE: Mannose-binding lectin (MBL)-associated serine protease1 (MASP1) is the central enzyme in the innate immune system, which has biological functions of antibacterial and anti-inflammatory activities.	Mannose	11-18	MBL associated serine protease 1	Bos taurus	69-74
30822514-0	2019	Production of recombinant human acid beta-glucosidase with high mannose-type N-glycans in rice gnt1 mutant for potential treatment of Gaucher disease.	Mannose	64-71	glucosylceramidase beta	Homo sapiens	32-53
30822514-2	2019	For uptake into macrophages, GBA needs to carry terminal mannose residues on their N-glycans.	Mannose	57-64	lysosomal acid glucosylceramidase	Cricetulus griseus	29-32
30822514-10	2019	The amounts of high mannose-type N-glycans were highly elevated in gnt1-GBA (100%) compared to WT-GBA (1%).	Mannose	20-27	lysosomal acid glucosylceramidase	Cricetulus griseus	72-75
30986866-0	2019	Reduced Mannose-Binding Lectin-Associated Serine Protease (MASP)-1 is Associated with Disturbed Coagulation in Septic Shock.	Mannose	8-15	MBL associated serine protease 1	Homo sapiens	59-66
31049543-2	2019	Structural characterization revealed that PSP-2 with a molecular weight of 144.8 kDa was composed of fucose (21.6%), arabinose (2.5%), galactose (22.4%), glucose (2.2%), xylose (18.8%), mannose (1.2%), glucuronic acid (7.7%) and galacturonic acid (23.6%).	Mannose	186-193	regenerating family member 1 beta	Homo sapiens	42-47
31093777-2	2019	With the knowledge that D-mannose is the natural ligand of mannose receptors and L-fucose is the key calcium chelator for tumor-associated carbohydrate antigens (TACAs) binding to E-selectin, herein, we firstly reported D-mannose polyethylene glycol (PEG) conjugates (Man-PEG) and L-fucose PEG conjugates (Fuc-PEG) co-modified liposomal doxorubicin (DOX-MFPL) to improve tumor-targeting ability.	Mannose	24-33	selectin E	Homo sapiens	180-190
31093777-2	2019	With the knowledge that D-mannose is the natural ligand of mannose receptors and L-fucose is the key calcium chelator for tumor-associated carbohydrate antigens (TACAs) binding to E-selectin, herein, we firstly reported D-mannose polyethylene glycol (PEG) conjugates (Man-PEG) and L-fucose PEG conjugates (Fuc-PEG) co-modified liposomal doxorubicin (DOX-MFPL) to improve tumor-targeting ability.	Mannose	220-229	selectin E	Homo sapiens	180-190
30735778-2	2019	Gas chromatography (GC) indicated that DAP was composed of galactose and mannose with a molar ratio of 1:1.	Mannose	73-80	death-associated protein	Rattus norvegicus	39-42
30877113-0	2019	Molecular Switch Controlling Expression of the Mannose-Specific Adhesin, Msa, in Lactobacillus plantarum.	Mannose	47-54	LPXTG cell wall anchor domain-containing protein	Lactobacillus plantarum WCFS1	73-76
30877113-3	2019	A straightforward correlation between the mannose adhesion capacity and domain composition of the mannose-specific adhesin (Msa) in the two strains has not been demonstrated previously.	Mannose	42-49	LPXTG cell wall anchor domain-containing protein	Lactobacillus plantarum WCFS1	124-127
30877113-3	2019	A straightforward correlation between the mannose adhesion capacity and domain composition of the mannose-specific adhesin (Msa) in the two strains has not been demonstrated previously.	Mannose	98-105	LPXTG cell wall anchor domain-containing protein	Lactobacillus plantarum WCFS1	124-127
30877113-4	2019	In this study, we analyzed the promoter regions upstream of the msa gene encoding a mannose-specific adhesin in these two strains.	Mannose	84-91	LPXTG cell wall anchor domain-containing protein	Lactobacillus plantarum WCFS1	64-67
30877113-12	2019	In Lactobacillus plantarum, interaction is mediated through bacterial surface proteins like Msa, which binds to mannose residues present on the intestinal cells.	Mannose	112-119	LPXTG cell wall anchor domain-containing protein	Lactobacillus plantarum WCFS1	92-95
30552791-3	2019	Here, we present the first structures of a mammalian beta-mannosidase in both the apo- and mannose-bound forms.	Mannose	91-98	mannosidase beta	Homo sapiens	53-69
30995222-5	2019	In complex with mannose-binding lectin-associated serine proteases (MASPs), collectin-11 may initiate the activation of complement, playing a role against pathogens, including T. cruzi.	Mannose	16-23	collectin subfamily member 11	Homo sapiens	76-88
30991766-5	2019	The results showed that PD1-1 is an inulin-type polysaccharide with a molecular weight of 2.6 kDa and is composed of glucose (52.39%), and mannose (45.41%).	Mannose	139-146	programmed cell death 1	Homo sapiens	24-29
30834312-1	2019	Up to ~20% of HIV-infected individuals eventually develop broadly neutralizing antibodies (bnAbs), and many of these antibodies (~40%) target a region of dense high-mannose glycosylation on gp120 of the HIV envelope protein, known as the "high-mannose patch" (HMP).	Mannose	165-172	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	190-195
30156702-0	2019	A glycoform of the secreted purple acid phosphatase AtPAP26 co-purifies with a mannose-binding lectin (AtGAL1) upregulated by phosphate-starved Arabidopsis.	Mannose	79-86	purple acid phosphatase 26	Arabidopsis thaliana	52-59
30156702-0	2019	A glycoform of the secreted purple acid phosphatase AtPAP26 co-purifies with a mannose-binding lectin (AtGAL1) upregulated by phosphate-starved Arabidopsis.	Mannose	79-86	Mevalonate/galactokinase family protein	Arabidopsis thaliana	103-109
30529353-3	2019	The monosaccharide compositions of SCP-1 were d-mannose, d-glucose and l-xylose with a molar ratio of 1.77:0.93:1 and that of the SCP-2 were d-mannose, l-rhamnose, d-glucose and l-xylose with a molar ratio of 5.27:1.21:0.16:1.	Mannose	46-55	stem cell proliferation 1	Mus musculus	35-40
30529353-3	2019	The monosaccharide compositions of SCP-1 were d-mannose, d-glucose and l-xylose with a molar ratio of 1.77:0.93:1 and that of the SCP-2 were d-mannose, l-rhamnose, d-glucose and l-xylose with a molar ratio of 5.27:1.21:0.16:1.	Mannose	141-150	sterol carrier protein 2, liver	Mus musculus	130-135
30521918-2	2019	MLP-1, with a molecular weight of 2,792,624 Da, consisted of arabinose, glucose, xylose, rhamnose, and mannose in a molar ratio of 1:1.13:2.35:6.74:8.85.	Mannose	103-110	ATP binding cassette subfamily C member 6	Rattus norvegicus	0-5
30740857-3	2019	CLEC4M binds to mannose-containing glycans on FVIII.	Mannose	16-23	C-type lectin domain family 4 member M	Homo sapiens	0-6
30740857-3	2019	CLEC4M binds to mannose-containing glycans on FVIII.	Mannose	16-23	coagulation factor VIII	Homo sapiens	46-51
30740857-13	2019	CLEC4M binding to recombinant FVIII was dependent on mannose-exposed N-linked glycans.	Mannose	53-60	C-type lectin domain family 4 member M	Homo sapiens	0-6
30740857-13	2019	CLEC4M binding to recombinant FVIII was dependent on mannose-exposed N-linked glycans.	Mannose	53-60	coagulation factor VIII	Homo sapiens	30-35
30740857-16	2019	Conclusions These findings suggest that CLEC4M is a novel clearance receptor that interacts with mannose-exposed glycans on FVIII in the presence or absence of VWF.	Mannose	97-104	C-type lectin domain family 4 member M	Homo sapiens	40-46
30740857-16	2019	Conclusions These findings suggest that CLEC4M is a novel clearance receptor that interacts with mannose-exposed glycans on FVIII in the presence or absence of VWF.	Mannose	97-104	coagulation factor VIII	Homo sapiens	124-129
30341950-0	2019	Lectin AtGAL1 interacts with high-mannose glycoform of the purple acid phosphatase AtPAP26 secreted by phosphate-starved Arabidopsis.	Mannose	34-41	Mevalonate/galactokinase family protein	Arabidopsis thaliana	7-13
30341950-0	2019	Lectin AtGAL1 interacts with high-mannose glycoform of the purple acid phosphatase AtPAP26 secreted by phosphate-starved Arabidopsis.	Mannose	34-41	purple acid phosphatase 26	Arabidopsis thaliana	83-90
30445446-3	2019	METHODS: By loading miR-146b mimic on mannose-modified trimethyl chitosan [MTC]-conjugated nanoparticles [NPs] [MTC-miR146b], a molecular targeted immunotherapeutic approach was developed to selectively target intestinal macrophages for mucosal regeneration and tumourigenesis in mouse models.	Mannose	38-45	microRNA 146b	Mus musculus	20-28
30445446-3	2019	METHODS: By loading miR-146b mimic on mannose-modified trimethyl chitosan [MTC]-conjugated nanoparticles [NPs] [MTC-miR146b], a molecular targeted immunotherapeutic approach was developed to selectively target intestinal macrophages for mucosal regeneration and tumourigenesis in mouse models.	Mannose	38-45	microRNA 146b	Mus musculus	116-123
30670593-3	2019	MS-based identification with immunochemical confirmation combined with gene ontology enrichment analysis revealed that ERp57 targets, among other substrates, components of the lectin pathway of complement activation: mannose-binding lectin, ficolin-2, ficolin-3, collectin-10, collectin-11, mannose-binding lectin-associated serine protease-1, and mannose-binding lectin-associated serine protease-2.	Mannose	217-224	protein disulfide isomerase family A member 3	Homo sapiens	119-124
30670593-3	2019	MS-based identification with immunochemical confirmation combined with gene ontology enrichment analysis revealed that ERp57 targets, among other substrates, components of the lectin pathway of complement activation: mannose-binding lectin, ficolin-2, ficolin-3, collectin-10, collectin-11, mannose-binding lectin-associated serine protease-1, and mannose-binding lectin-associated serine protease-2.	Mannose	291-298	protein disulfide isomerase family A member 3	Homo sapiens	119-124
30949171-5	2019	Functional activities of the ficolin-3-mediated lectin (F3-LP), mannose binding lectin-mediated lectin- (MBL-LP), classical (CP), and alternative pathways (AP), as well as concentrations of complement activation products C4d and sC5b-9 were determined.	Mannose	64-71	mannose binding lectin 2	Homo sapiens	105-108
30949171-5	2019	Functional activities of the ficolin-3-mediated lectin (F3-LP), mannose binding lectin-mediated lectin- (MBL-LP), classical (CP), and alternative pathways (AP), as well as concentrations of complement activation products C4d and sC5b-9 were determined.	Mannose	64-71	ceruloplasmin	Homo sapiens	125-127
30834312-1	2019	Up to ~20% of HIV-infected individuals eventually develop broadly neutralizing antibodies (bnAbs), and many of these antibodies (~40%) target a region of dense high-mannose glycosylation on gp120 of the HIV envelope protein, known as the "high-mannose patch" (HMP).	Mannose	244-251	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	190-195
30727738-3	2019	In this regard, herein the authors report a direct coupling of mannose probes with bovine serum albumin (BSA) layer on the gold substrate via a squaric acid-mediated reaction under mild conditions, in which the BSA layer provides not only reactive amine groups but also a nonfouling surface property.	Mannose	63-70	albumin	Homo sapiens	90-103
30996807-4	2019	We report herein a straightforward synthetic strategy to afford C-2 substituted trihydroxypiperidines with different alkyl chains starting from low cost d-mannose.	Mannose	153-162	complement C2	Homo sapiens	64-67
30723261-2	2019	In addition, it has been shown that serum sensitive isolates are (partially) protected by the Ixodes Tick Salivary Lectin Pathway Inhibitor (TSLPI) protein; a salivary gland protein that inhibits the function of Mannose Binding Lectin (MBL).	Mannose	212-219	mannose binding lectin 2	Homo sapiens	236-239
30564965-4	2019	Higher reactivity of alpha2M with several lectins was detected in older individuals indicating an increased content of specific monosaccharides: alpha2,6 sialic acid, mannose and N-acetylglucosamine, and multiantennary complex type N-glycans.	Mannose	167-174	alpha-2-macroglobulin	Homo sapiens	21-28
30391591-3	2019	The composition and proportion of BSP-1 and BSP-2 were mannose and glucose in molar ratios of 4.0:1.0 and 3.0:1.0 respectively.	Mannose	55-62	kallikrein related-peptidase 8	Mus musculus	34-39
30525661-2	2019	In this study, the preclinical safety of an HIV-1 gp120 and mannose responsive microbicide delivery system (MRP) is evaluated in C57BL/6 mice.	Mannose	60-67	ATP binding cassette subfamily C member 1	Homo sapiens	108-111
30543411-0	2019	Binding of the Bacterial Adhesin FimH to Its Natural, Multivalent High-Mannose Type Glycan Targets.	Mannose	71-78	adhesin	Escherichia coli	25-32
30543411-3	2019	Here, we characterize the interactions between the fimbrial adhesin FimH from uropathogenic Escherichia coli strains and its natural high-mannose type N-glycan binding epitopes on uroepithelial glycoproteins.	Mannose	138-145	adhesin	Escherichia coli	60-67
30606111-4	2019	Plasma concentrations of MBL were obtained by an enzyme-linked immunosorbent assay (ELISA) using a commercial Human Mannose Binding Lectin kit (MyBioSource, Inc.) that was performed according to the manufacturer"s guidelines, with values &lt; 100 ng/ml considered deficient.	Mannose	116-123	mannose binding lectin 2	Homo sapiens	25-28
30366547-5	2019	As indicated by monosaccharides components analysis, the major component BS-2 mainly consisted of galactose, glucose, and mannose with average molecular weight (Mw) of 1.765 x 104 Da.	Mannose	122-129	alkylglycerone phosphate synthase	Mus musculus	73-77
30584101-1	2019	Heteromannan (HM) is one of the most ancient cell wall polymers in the plant kingdom, consisting of beta-(1-4)-linked backbones of glucose (Glc) and mannose (Man) units.	Mannose	149-156	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	100-109
32254924-6	2018	beta-CD decorated with biotin (CD-B) and/or mannose (CD-M) was attached to the PDMS-POA microchannels via host-guest interactions between the adamantane and beta-CD moieties.	Mannose	44-51	B cell receptor associated protein 31	Homo sapiens	53-57
30806252-3	2019	The results indicated that FPS was mainly composed of mannose; IPS, of glucose; and EPS, of galactose.	Mannose	54-61	farnesyl diphosphate synthetase	Mus musculus	27-30
30241853-2	2018	Chemical analysis demonstrated that SHP was primarily composed of mannose, glucuronic acid, glucose, fucose, galactose, xylose and rahmnose with a molar ratio of 1.00:0.85:0.84:0.58:0.30:0.37:0.15.	Mannose	66-73	nuclear receptor subfamily 0, group B, member 2	Mus musculus	36-39
30534205-0	2018	Fasting plasma mannose levels are associated with insulin sensitivity independent of BMI in Japanese individuals with diabetes.	Mannose	15-22	insulin	Homo sapiens	50-57
30534205-2	2018	In addition, fasting plasma mannose levels (M0) are associated with insulin resistance independent of BMI.	Mannose	28-35	insulin	Homo sapiens	68-75
30534205-3	2018	Since the association between mannose and insulin sensitivity (IS) in those with impaired glucose tolerance remains unknown, we aimed to investigate this association in individuals without severe obesity but with varying degrees of glucose tolerance.	Mannose	30-37	insulin	Homo sapiens	42-49
30287368-3	2018	Results showed that PIP-1 had a high molecular weight, a high intrinsic viscosity and a linear repeating backbone composed of glucopyranose (Glcp), galactopyranose, and mannopyranose joined by alpha-(1   4), alpha-(1   3), and alpha-(1   6) linkages, and single alpha-terminal-D-Glcp as side chains 6-O-linked to the main chain according to the GC-MS and NMR results, and exhibited triple helical structure.	Mannose	169-182	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	20-25
29947113-3	2018	MAN1B1 encodes an alpha1,2-mannosidase that removes the terminal mannose residue from the middle branch.	Mannose	65-72	mannosidase alpha class 1B member 1	Homo sapiens	0-6
29947113-3	2018	MAN1B1 encodes an alpha1,2-mannosidase that removes the terminal mannose residue from the middle branch.	Mannose	65-72	mannosidase alpha class 1A member 2	Homo sapiens	18-38
29069492-1	2018	Zymogen granule protein 16 (ZG16p) is a soluble lectin that binds to both mannose and heparin/heparan sulfate.	Mannose	74-81	zymogen granule protein 16	Homo sapiens	0-26
29069492-1	2018	Zymogen granule protein 16 (ZG16p) is a soluble lectin that binds to both mannose and heparin/heparan sulfate.	Mannose	74-81	zymogen granule protein 16	Homo sapiens	28-33
30251341-2	2018	Mannose-binding C-type lectins, which primarily include mannose receptor (MR, CD206) and dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), are highly expressed on various cancer cells, endothelial cells, macrophages, and dendritic cells (DCs), which make them attractive targets for therapeutic effect.	Mannose	0-7	mannose receptor C-type 1	Homo sapiens	56-72
30251341-2	2018	Mannose-binding C-type lectins, which primarily include mannose receptor (MR, CD206) and dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), are highly expressed on various cancer cells, endothelial cells, macrophages, and dendritic cells (DCs), which make them attractive targets for therapeutic effect.	Mannose	0-7	mannose receptor C-type 1	Homo sapiens	74-76
30251341-2	2018	Mannose-binding C-type lectins, which primarily include mannose receptor (MR, CD206) and dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), are highly expressed on various cancer cells, endothelial cells, macrophages, and dendritic cells (DCs), which make them attractive targets for therapeutic effect.	Mannose	0-7	CD209 molecule	Homo sapiens	89-168
30251341-2	2018	Mannose-binding C-type lectins, which primarily include mannose receptor (MR, CD206) and dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN), are highly expressed on various cancer cells, endothelial cells, macrophages, and dendritic cells (DCs), which make them attractive targets for therapeutic effect.	Mannose	0-7	CD209 molecule	Homo sapiens	170-177
30443026-3	2018	Purified M. tuberculosis mannose-capped lipoarabinomannan (ManLAM) was shown to induce signaling via Dectin-2, an activity that requires the (alpha1   2)-linked mannosides forming the caps.	Mannose	25-32	C-type lectin domain containing 6A	Homo sapiens	101-109
30296068-3	2018	N-Glycans such as high mannose, complex, and hybrid types were identified in buffalo and goat LPO.	Mannose	23-30	lactoperoxidase	Capra hircus	94-97
30389923-3	2018	PDGFRA Y288C, an extracellular domain mutation, is primarily high mannose glycosylated consistent with trapping in the endoplasmic reticulum (ER).	Mannose	66-73	platelet derived growth factor receptor alpha	Homo sapiens	0-6
30464341-6	2018	As a result, the administration of mannose in combination with conventional chemotherapy affects levels of anti-apoptotic proteins of the Bcl-2 family, leading to sensitization to cell death.	Mannose	35-42	BCL2 apoptosis regulator	Homo sapiens	138-143
30464341-7	2018	Finally we show that susceptibility to mannose is dependent on the levels of phosphomannose isomerase (PMI).	Mannose	39-46	mannose phosphate isomerase	Homo sapiens	77-101
30464341-7	2018	Finally we show that susceptibility to mannose is dependent on the levels of phosphomannose isomerase (PMI).	Mannose	39-46	mannose phosphate isomerase	Homo sapiens	103-106
30464341-8	2018	Cells with low levels of PMI are sensitive to mannose, whereas cells with high levels are resistant, but can be made sensitive by RNA-interference-mediated depletion of the enzyme.	Mannose	46-53	mannose phosphate isomerase	Homo sapiens	25-28
30464341-9	2018	In addition, we use tissue microarrays to show that PMI levels also vary greatly between different patients and different tumour types, indicating that PMI levels could be used as a biomarker to direct the successful administration of mannose.	Mannose	235-242	mannose phosphate isomerase	Homo sapiens	52-55
30464341-9	2018	In addition, we use tissue microarrays to show that PMI levels also vary greatly between different patients and different tumour types, indicating that PMI levels could be used as a biomarker to direct the successful administration of mannose.	Mannose	235-242	mannose phosphate isomerase	Homo sapiens	152-155
30377844-6	2018	DLP-1 was composed of D-(+)-galactose, DL-arabinose, and L-(+)-rhamnose with a molar ratio of 3.21:1.11:0.23, and traces of D-xylose, D-glucose, and D-(+)-mannose.	Mannose	149-162	dynamin 1 like	Homo sapiens	0-5
29969638-2	2018	The physicochemical evaluations indicate that FPS is mainly composed of glucose, mannose, galactose, fucose, arabinose and glucuronic acid with the mole percentages of 70.30%, 8.70%, 12.88%, 0.79%, 5.04% and 1.57%, respectively.	Mannose	81-88	farnesyl diphosphate synthase	Homo sapiens	46-49
29752722-4	2018	In our study, we developed a novel DC-targeted siRNA delivery system, man-GNR-siIDO, using as a nanocarrier of siRNA specific for IDO (siIDO) and mannose (man) as a guide molecule for targeting DCs.	Mannose	146-153	indoleamine 2,3-dioxygenase 1	Homo sapiens	80-83
30305426-6	2018	In HeLa cell membranes, stress-independent XBP1s activation increased the population of high-mannose and tetraantennary N-glycans, and also enhanced core fucosylation.	Mannose	93-100	X-box binding protein 1	Homo sapiens	43-47
30344001-2	2018	Starting from libraries of 108 mannose-conjugated peptides, we identified glycopeptides that exhibited up to a 650-fold increase in multivalent binding affinity for DC-SIGN, which is also preserved in cells.	Mannose	31-38	CD209 molecule	Homo sapiens	165-172
30393476-1	2018	Introduction: The association of mannose-binding lectin gene (MBL2) polymorphisms with tuberculosis susceptibility was inconclusive.	Mannose	33-40	mannose binding lectin 2	Homo sapiens	62-66
29981898-5	2018	Using an off-line HPLC-MALDI-TOF-MS approach combined with exoglycosidase digestions and MS/MS, we reveal that the multiple hexose residues of the N-glycans of the gly-12;gly-13;gly-14 triple mutant are not just mannose, but include galactoses in three different positions (beta-intersecting, beta-bisecting and alpha-terminal) on isomeric forms of Hex4-8HexNAc2 structures; some of these structures are fucosylated and/or methylated.	Mannose	212-219	GLYcosylation related	Caenorhabditis elegans	164-170
29981898-5	2018	Using an off-line HPLC-MALDI-TOF-MS approach combined with exoglycosidase digestions and MS/MS, we reveal that the multiple hexose residues of the N-glycans of the gly-12;gly-13;gly-14 triple mutant are not just mannose, but include galactoses in three different positions (beta-intersecting, beta-bisecting and alpha-terminal) on isomeric forms of Hex4-8HexNAc2 structures; some of these structures are fucosylated and/or methylated.	Mannose	212-219	Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Caenorhabditis elegans	171-177
29981898-5	2018	Using an off-line HPLC-MALDI-TOF-MS approach combined with exoglycosidase digestions and MS/MS, we reveal that the multiple hexose residues of the N-glycans of the gly-12;gly-13;gly-14 triple mutant are not just mannose, but include galactoses in three different positions (beta-intersecting, beta-bisecting and alpha-terminal) on isomeric forms of Hex4-8HexNAc2 structures; some of these structures are fucosylated and/or methylated.	Mannose	212-219	GLYcosylation related	Caenorhabditis elegans	178-184
29802924-2	2018	Physicochemical analysis showed that RRP1 was composed of mannose, rhamnose, galacturonic acid, glucose, galactose and arabinose with a relative molar ratio of 0.69:0.11:0.15:1:0.51:7.5 and RRP2 was consisted of mannose, rhamnose, galacturonic acid, glucose, galactose and arabinose (relative molar ratio = 0.15:0.19:1.01:0.18:0.47:1).	Mannose	58-65	ribosomal RNA processing 1	Mus musculus	37-41
30133879-6	2018	We also found that CWH43 is genetically related to TED1, which encodes a protein involved in the removal of the ethanolamine phosphate from the second mannose residue in GPI glycan moieties.	Mannose	151-158	Cwh43p	Saccharomyces cerevisiae S288C	19-24
30133879-6	2018	We also found that CWH43 is genetically related to TED1, which encodes a protein involved in the removal of the ethanolamine phosphate from the second mannose residue in GPI glycan moieties.	Mannose	151-158	Ted1p	Saccharomyces cerevisiae S288C	51-55
29939232-3	2018	Alg1, a beta-1, 4 mannosyltransferase (MTase) physically interacts with Alg2 and Alg11 proteins to form the multienzyme complex which catalyzes the addition of all five mannose to generate the Man5GlcNAc2-PP-Dol intermediate.	Mannose	169-176	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	0-4
29939232-3	2018	Alg1, a beta-1, 4 mannosyltransferase (MTase) physically interacts with Alg2 and Alg11 proteins to form the multienzyme complex which catalyzes the addition of all five mannose to generate the Man5GlcNAc2-PP-Dol intermediate.	Mannose	169-176	GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	72-76
29939232-3	2018	Alg1, a beta-1, 4 mannosyltransferase (MTase) physically interacts with Alg2 and Alg11 proteins to form the multienzyme complex which catalyzes the addition of all five mannose to generate the Man5GlcNAc2-PP-Dol intermediate.	Mannose	169-176	alpha-1,2-mannosyltransferase ALG11	Saccharomyces cerevisiae S288C	81-86
29802924-2	2018	Physicochemical analysis showed that RRP1 was composed of mannose, rhamnose, galacturonic acid, glucose, galactose and arabinose with a relative molar ratio of 0.69:0.11:0.15:1:0.51:7.5 and RRP2 was consisted of mannose, rhamnose, galacturonic acid, glucose, galactose and arabinose (relative molar ratio = 0.15:0.19:1.01:0.18:0.47:1).	Mannose	212-219	ribosomal RNA processing 1	Mus musculus	37-41
29802924-3	2018	Periodate oxidation and Smith degradation analysis revealed that, in RRP1, part of the arabinose and glucose residues were 1   3,6/1   3/1   2,3/1   3,4/1   2,4/1   2,3,4-linked, and the mannose, rhamnose and galactose residues were 1   2,6/1   6/1   2/1 /1   4,6/1   4-linked.	Mannose	187-194	ribosomal RNA processing 1	Mus musculus	69-73
29802924-4	2018	In RRP2, the rhamnose, glucose and galactose residues were linked by 1   3,6/1   3/1   2,3/1   3,4/1   2,4/1   2,3,4 linkages, and the arabinose and mannose residues were 1   2/1   6/1   4-linked.	Mannose	149-156	ribosome binding protein 1	Mus musculus	3-7
29509998-3	2018	Mannose-binding lectins surfactant protein D (SP-D), cyanovirin-N (CV-N) and human mannose-binding lectin (hMBL) also induce salicylic acid (SA)-dependent HR-like cell death in N. benthamiana, and this effect is mediated by the lectin"s glycan binding activity.	Mannose	0-7	surfactant protein D	Homo sapiens	46-50
29509998-3	2018	Mannose-binding lectins surfactant protein D (SP-D), cyanovirin-N (CV-N) and human mannose-binding lectin (hMBL) also induce salicylic acid (SA)-dependent HR-like cell death in N. benthamiana, and this effect is mediated by the lectin"s glycan binding activity.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	83-105
30271438-0	2018	D-Mannose Enhanced Immunomodulation of Periodontal Ligament Stem Cells via Inhibiting IL-6 Secretion.	Mannose	0-9	interleukin 6	Homo sapiens	86-90
30063822-3	2018	Recombinantly expressing glycoproteins in HEK293S (GnT1-) cells results in N-glycans with high-mannose structures that can be processed to leave a single GlcNAc residue.	Mannose	95-102	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	51-55
30271438-6	2018	We found that less IL-6 could be detected in D-mannose-pretreated hPDLSCs.	Mannose	45-54	interleukin 6	Homo sapiens	19-23
30271438-7	2018	In the D-mannose pretreatment group, induced Treg cell number would decrease if increased IL-6 levels could be detected.	Mannose	9-16	interleukin 6	Homo sapiens	90-94
29525161-5	2018	SLP-2, with a molecular weight of 44 KDa, was mainly composed of mannose, galacturonic acid, galactose and arabinose in a molar ratio of 11.5:69.5:9.3:8.2.	Mannose	65-72	synaptotagmin like 2	Homo sapiens	0-5
29683392-1	2018	Polymannose (PM) having a weight-average molar mass (Mw) of 30-53 kDa was synthesized by the polycondensation of mannose using phosphorous acid as the catalyst and characterized by various techniques such as NMR, IR, GPC and polarimetry.	Mannose	4-11	glycophorin C (Gerbich blood group)	Homo sapiens	217-220
30030325-0	2018	Mannose Metabolism Is Essential for Th1 Cell Differentiation and IFN-gamma Production.	Mannose	0-7	negative elongation factor complex member C/D, Th1l	Mus musculus	36-39
30030325-0	2018	Mannose Metabolism Is Essential for Th1 Cell Differentiation and IFN-gamma Production.	Mannose	0-7	interferon gamma	Mus musculus	65-74
30030325-2	2018	In this work, we show that mannose metabolism is essential for IFN-gamma production by mouse Th1 cells.	Mannose	27-34	interferon gamma	Mus musculus	63-72
30030325-2	2018	In this work, we show that mannose metabolism is essential for IFN-gamma production by mouse Th1 cells.	Mannose	27-34	negative elongation factor complex member C/D, Th1l	Mus musculus	93-96
30030325-3	2018	In addition, we demonstrate that the susceptibility of Th1 cells to glycolysis restriction depends on the activation conditions and that under diminished glycolytic flux, mannose availability becomes the limiting factor for IFN-gamma expression.	Mannose	171-178	negative elongation factor complex member C/D, Th1l	Mus musculus	55-58
30030325-3	2018	In addition, we demonstrate that the susceptibility of Th1 cells to glycolysis restriction depends on the activation conditions and that under diminished glycolytic flux, mannose availability becomes the limiting factor for IFN-gamma expression.	Mannose	171-178	interferon gamma	Mus musculus	224-233
29655744-5	2018	HP1 and HP2 had the same monosaccharide species and manganese contents, but differed in their molar rhamnose, arabinose, mannose, glucose, galactose and uronic acid contents (7.32 and 35.9%, as galacturonic acid), Mw (68.7 and 111 kDa, respectively), and contents of K, Cr, Cu, Zn, Pb and Ca.	Mannose	121-128	chromobox 5	Mus musculus	0-3
30073131-10	2018	The extracted polysaccharides composed of mannose, galactose, glucose, arabinose, xylose and rhamanose, with highest percentage of mannose (62.49%) and galactose (25.42%) in SPCA.	Mannose	131-138	coagulation factor VII	Homo sapiens	174-178
29718541-6	2018	Both participate in Nox1 trafficking, as Nox1 advances to the cell surface in two differentially N-glycosylated forms, one complex and one high mannose, in a Sar1/Stx5-dependent and -independent manner, respectively.	Mannose	144-151	NADPH oxidase 1	Homo sapiens	20-24
29718541-6	2018	Both participate in Nox1 trafficking, as Nox1 advances to the cell surface in two differentially N-glycosylated forms, one complex and one high mannose, in a Sar1/Stx5-dependent and -independent manner, respectively.	Mannose	144-151	NADPH oxidase 1	Homo sapiens	41-45
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Mannose	279-286	cytochrome b-245 beta chain	Homo sapiens	0-4
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Mannose	279-286	NADPH oxidase 5	Homo sapiens	9-13
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Mannose	279-286	cytochrome b-245 beta chain	Homo sapiens	75-79
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Mannose	279-286	secretion associated Ras related GTPase 1A	Homo sapiens	133-137
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Mannose	279-286	NADPH oxidase 5	Homo sapiens	171-175
29963999-0	2018	Dibutyryl cAMP- or Interleukin-6-induced astrocytic differentiation enhances mannose binding lectin (MBL)-associated serine protease (MASP)-1/3 expression in C6 glioma cells.	Mannose	77-84	cathelicidin antimicrobial peptide	Homo sapiens	10-15
29963999-0	2018	Dibutyryl cAMP- or Interleukin-6-induced astrocytic differentiation enhances mannose binding lectin (MBL)-associated serine protease (MASP)-1/3 expression in C6 glioma cells.	Mannose	77-84	interleukin 6	Homo sapiens	19-32
29963999-0	2018	Dibutyryl cAMP- or Interleukin-6-induced astrocytic differentiation enhances mannose binding lectin (MBL)-associated serine protease (MASP)-1/3 expression in C6 glioma cells.	Mannose	77-84	mannose binding lectin 2	Homo sapiens	101-104
29963999-0	2018	Dibutyryl cAMP- or Interleukin-6-induced astrocytic differentiation enhances mannose binding lectin (MBL)-associated serine protease (MASP)-1/3 expression in C6 glioma cells.	Mannose	77-84	MBL associated serine protease 1	Homo sapiens	117-141
30135690-5	2018	The serine proteases (MASP-1/2/3, factor D, factor B), which are responsible for the activation of the cascade, are straightforward targets of inhibition, but the pattern recognition molecules (mannose-binding lectin, other collectins, and ficolins), the regulatory components (factor H, factor I, properdin), and C3 are also subjects of drug development.	Mannose	194-201	MBL associated serine protease 1	Homo sapiens	22-52
30087939-1	2018	As observed for the reference PSMA I&amp;T, the natGa/natLu complexes of the respective galactose-, mannose-, and cellobiose-conjugated analogs showed high PSMA affinity.	Mannose	100-107	folate hydrolase 1	Homo sapiens	30-34
30087939-1	2018	As observed for the reference PSMA I&amp;T, the natGa/natLu complexes of the respective galactose-, mannose-, and cellobiose-conjugated analogs showed high PSMA affinity.	Mannose	100-107	folate hydrolase 1	Homo sapiens	156-160
30052682-5	2018	gB possesses seven N-glycosylation sites, and FBXO2 directly binds to these high-mannose moieties through its sugar-binding domain.	Mannose	81-88	F-box protein 2	Homo sapiens	46-51
29784879-0	2018	ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3).	Mannose	44-51	thioredoxin domain containing 5	Homo sapiens	0-22
29784879-0	2018	ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3).	Mannose	44-51	thioredoxin domain containing 5	Homo sapiens	24-29
29784879-0	2018	ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3).	Mannose	44-51	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	73-130
29784879-0	2018	ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3).	Mannose	44-51	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	132-137
29784879-5	2018	However, the molecular mechanism of mannose removal by EDEMs remains unclear, partly owing to the difficulty of reconstituting mannosidase activity in vitro Here, our analysis of EDEM3-mediated mannose-trimming activity on a misfolded glycoprotein revealed that ERp46, an ER-resident oxidoreductase, associates stably with EDEM3.	Mannose	36-43	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	179-184
29784879-5	2018	However, the molecular mechanism of mannose removal by EDEMs remains unclear, partly owing to the difficulty of reconstituting mannosidase activity in vitro Here, our analysis of EDEM3-mediated mannose-trimming activity on a misfolded glycoprotein revealed that ERp46, an ER-resident oxidoreductase, associates stably with EDEM3.	Mannose	36-43	thioredoxin domain containing 5	Homo sapiens	262-267
29784879-5	2018	However, the molecular mechanism of mannose removal by EDEMs remains unclear, partly owing to the difficulty of reconstituting mannosidase activity in vitro Here, our analysis of EDEM3-mediated mannose-trimming activity on a misfolded glycoprotein revealed that ERp46, an ER-resident oxidoreductase, associates stably with EDEM3.	Mannose	36-43	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	323-328
29784879-5	2018	However, the molecular mechanism of mannose removal by EDEMs remains unclear, partly owing to the difficulty of reconstituting mannosidase activity in vitro Here, our analysis of EDEM3-mediated mannose-trimming activity on a misfolded glycoprotein revealed that ERp46, an ER-resident oxidoreductase, associates stably with EDEM3.	Mannose	194-201	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	179-184
29784879-5	2018	However, the molecular mechanism of mannose removal by EDEMs remains unclear, partly owing to the difficulty of reconstituting mannosidase activity in vitro Here, our analysis of EDEM3-mediated mannose-trimming activity on a misfolded glycoprotein revealed that ERp46, an ER-resident oxidoreductase, associates stably with EDEM3.	Mannose	194-201	thioredoxin domain containing 5	Homo sapiens	262-267
29784879-5	2018	However, the molecular mechanism of mannose removal by EDEMs remains unclear, partly owing to the difficulty of reconstituting mannosidase activity in vitro Here, our analysis of EDEM3-mediated mannose-trimming activity on a misfolded glycoprotein revealed that ERp46, an ER-resident oxidoreductase, associates stably with EDEM3.	Mannose	194-201	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	323-328
29784879-7	2018	In a defined in vitro system consisting of recombinant proteins purified from HEK293 cells, the mannose-trimming activity of EDEM3 toward the model misfolded substrate, the glycoprotein T-cell receptor alpha locus (TCRalpha), was reconstituted only when ERp46 had established a covalent interaction with EDEM3.	Mannose	96-103	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	125-130
29784879-7	2018	In a defined in vitro system consisting of recombinant proteins purified from HEK293 cells, the mannose-trimming activity of EDEM3 toward the model misfolded substrate, the glycoprotein T-cell receptor alpha locus (TCRalpha), was reconstituted only when ERp46 had established a covalent interaction with EDEM3.	Mannose	96-103	T cell receptor alpha locus	Homo sapiens	186-213
29784879-7	2018	In a defined in vitro system consisting of recombinant proteins purified from HEK293 cells, the mannose-trimming activity of EDEM3 toward the model misfolded substrate, the glycoprotein T-cell receptor alpha locus (TCRalpha), was reconstituted only when ERp46 had established a covalent interaction with EDEM3.	Mannose	96-103	T cell receptor alpha locus	Homo sapiens	215-223
29784879-7	2018	In a defined in vitro system consisting of recombinant proteins purified from HEK293 cells, the mannose-trimming activity of EDEM3 toward the model misfolded substrate, the glycoprotein T-cell receptor alpha locus (TCRalpha), was reconstituted only when ERp46 had established a covalent interaction with EDEM3.	Mannose	96-103	thioredoxin domain containing 5	Homo sapiens	254-259
29784879-7	2018	In a defined in vitro system consisting of recombinant proteins purified from HEK293 cells, the mannose-trimming activity of EDEM3 toward the model misfolded substrate, the glycoprotein T-cell receptor alpha locus (TCRalpha), was reconstituted only when ERp46 had established a covalent interaction with EDEM3.	Mannose	96-103	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	304-309
29518405-2	2018	Recently, a protein harboring DM9 repeats was identified as mannose-specific lectin (CgCGL1, renamed as CgDM9CP-1) from the Pacific oyster Crassostrea gigas.	Mannose	60-67	Cyclic-AMP response element binding protein B	Drosophila melanogaster	30-33
29738673-1	2018	High-mannose-type N-glycans are an important component of neutralizing epitopes on HIV-1 envelope glycoprotein gp120.	Mannose	5-12	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	111-116
29218650-2	2018	LEP-2a was identified to be a homogeneous component with an average molecular weight of 1.31 x 106 Da, which was consisted of mannose and galactose in a molar ratio of 3.8:1.0.	Mannose	126-133	late cornified envelope 1B	Homo sapiens	0-5
29892304-4	2018	Mannose-binding lectin (MBL)-associated serine proteases (MASPs), which are associated with humoral pattern recognition molecules (MBL or ficolins), are the enzymatic constituents of the LP and AP.	Mannose	0-7	mannose-binding lectin (protein C) 2	Mus musculus	24-27
29892304-4	2018	Mannose-binding lectin (MBL)-associated serine proteases (MASPs), which are associated with humoral pattern recognition molecules (MBL or ficolins), are the enzymatic constituents of the LP and AP.	Mannose	0-7	mannose-binding lectin (protein C) 2	Mus musculus	131-134
29854737-1	2018	Mannose-binding lectin (MBL) is one of the key players in the innate immune system.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
29409894-10	2018	Taken together, these results suggest that MNS1/2-mediated mannose trimming of N-glycans is crucial in modulating glycoprotein abundance to withstand salt stress in plants.	Mannose	59-66	alpha-mannosidase 1	Arabidopsis thaliana	43-47
32290990-2	2018	Among these, 2-deoxy-D-glucose and D-mannose are substrates for hexokinase (HXK).	Mannose	35-44	hexokinase	Arabidopsis thaliana	76-79
29686372-0	2018	Rgg-Shp regulators are important for pneumococcal colonization and invasion through their effect on mannose utilization and capsule synthesis.	Mannose	100-107	nuclear receptor subfamily 0 group B member 2	Homo sapiens	4-7
29686372-4	2018	We find that both of these QS circuits are induced by short hydrophobic peptides (Shp) upon sensing sugars found in the respiratory tract, such as galactose and mannose.	Mannose	161-168	nuclear receptor subfamily 0 group B member 2	Homo sapiens	54-80
29686372-4	2018	We find that both of these QS circuits are induced by short hydrophobic peptides (Shp) upon sensing sugars found in the respiratory tract, such as galactose and mannose.	Mannose	161-168	nuclear receptor subfamily 0 group B member 2	Homo sapiens	82-85
32290990-2	2018	Among these, 2-deoxy-D-glucose and D-mannose are substrates for hexokinase (HXK).	Mannose	35-44	hexokinase	Arabidopsis thaliana	64-74
29137999-4	2018	Lectin microarray analysis demonstrated increased glycosylation of fibrinogen due to aging, with predominant increase in high-mannose or hybrid type N-glycans, as well as tri-/tetraantennary complex N-glycans with greater content of galactose and N-acetylglucosamine residues.	Mannose	126-133	fibrinogen beta chain	Homo sapiens	67-77
29155159-3	2018	PRG1-1 was composed of glucose, galactose, mannose, xylose and fructose, in a molar ratio of 66.5:29.2:3.17: 0.663:0.447, respectively.	Mannose	43-50	PRG1	Homo sapiens	0-4
29330473-8	2018	Compared to healthy controls, diabetic Ndst1 f/f Tie2Cre - mice showed increased glomerular macrophage infiltration, mannose binding lectin complement deposition and glomerulosclerosis, whereas these pathological reactions were prevented significantly in the diabetic Ndst1 f/f Tie2Cre + animals (all three p &lt; 0.01).	Mannose	117-124	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	Mus musculus	39-44
29579062-10	2018	In addition, while Env of viruses enriched with mannose-type glycans were sensitive to Endo-H deglycosylation, Env of untreated viruses were partially resistant, indicating that HIV-1 Env glycans are heterogeneously comprised of complex, hybrid, and mannose types.	Mannose	48-55	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	19-22
29367433-7	2018	N-glycans presented in each chromatographic peak were elucidated using MALDI-TOF/TOF-MS. We detected changes in the N-glycosylation pattern of the lysosomal glycocalyx of NPC1-null versus wt cells which involved high-mannose and sialylated N-glycans.	Mannose	217-224	NPC intracellular cholesterol transporter 1	Homo sapiens	171-175
29507546-6	2018	Moreover, the levels of N-acetylgalactosamine, mannose, galactose, N-acetylglucosamine on CEA showed a downward trend after first experiencing an increase at Stage II with the stages of CRC.	Mannose	47-54	CEA cell adhesion molecule 3	Homo sapiens	90-93
29306566-0	2018	Bispecific chimeric antigen receptors targeting the CD4 binding site and high-mannose Glycans of gp120 optimized for anti-human immunodeficiency virus potency and breadth with minimal immunogenicity.	Mannose	78-85	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	97-102
29306566-10	2018	By contrast, the CD4-langerin and CD4-mannose binding lectin (MBL) CARs uniformly displayed enhanced potency compared with the CD4 CAR against all the genetically diverse HIV-1 isolates examined.	Mannose	38-45	CD4 molecule	Homo sapiens	34-37
29306566-10	2018	By contrast, the CD4-langerin and CD4-mannose binding lectin (MBL) CARs uniformly displayed enhanced potency compared with the CD4 CAR against all the genetically diverse HIV-1 isolates examined.	Mannose	38-45	mannose binding lectin 2	Homo sapiens	62-65
29306566-10	2018	By contrast, the CD4-langerin and CD4-mannose binding lectin (MBL) CARs uniformly displayed enhanced potency compared with the CD4 CAR against all the genetically diverse HIV-1 isolates examined.	Mannose	38-45	CD4 molecule	Homo sapiens	34-37
28742273-5	2018	We also used the same technique to demonstrate that these spectral markers (alpha-helix/beta-sheet ratio, glucose and mannose) are recovering to basal levels upon anti-TNFalpha therapy.	Mannose	118-125	tumor necrosis factor	Mus musculus	168-176
29254034-2	2018	REPS2-A was composed of galactose, arabinose, glucose, and mannose at a molar ratio of 63.1:0.2:18.3:18.3, respectively, with a molecular weight of 7.125x106Da.	Mannose	59-66	RALBP1 associated Eps domain containing 2	Homo sapiens	0-5
29513319-7	2018	As a result, Se-RLFP-1 was found to be mainly composed of mannose, glucose, galactose and xylose in a molar ratio of 1.4 : 7.9 : 1.0 : 1.5, while Se-RLFP-2 was composed of mannose, rhamnose, glucose, galactose and xylose (12.6 : 1.0 : 38.3 : 5.6 : 19.6).	Mannose	58-65	RLF pseudogene 1	Homo sapiens	16-22
29513319-7	2018	As a result, Se-RLFP-1 was found to be mainly composed of mannose, glucose, galactose and xylose in a molar ratio of 1.4 : 7.9 : 1.0 : 1.5, while Se-RLFP-2 was composed of mannose, rhamnose, glucose, galactose and xylose (12.6 : 1.0 : 38.3 : 5.6 : 19.6).	Mannose	172-179	RLF pseudogene 1	Homo sapiens	16-22
29556352-0	2018	The enhanced antitumor-specific immune response with mannose- and CpG-ODN-coated liposomes delivering TRP2 peptide.	Mannose	53-60	tRNA proline 2	Mus musculus	102-106
29274553-6	2018	Unique NOE correlations between core-mannose and the alpha1-3 branch mannose as well as the 3JC-H constant of the glycoside linkage indicate that bisecting GlcNAc restricts the conformation of the 1-3 branch.	Mannose	37-44	adrenoceptor alpha 1D	Homo sapiens	53-61
29274553-6	2018	Unique NOE correlations between core-mannose and the alpha1-3 branch mannose as well as the 3JC-H constant of the glycoside linkage indicate that bisecting GlcNAc restricts the conformation of the 1-3 branch.	Mannose	69-76	adrenoceptor alpha 1D	Homo sapiens	53-61
29274553-7	2018	The angles of the glycosidic bonds between core-mannose and alpha1-6 branch mannose derived from 3JC-H and 3JH-H coupling constants show that terminal GlcNAcs restrict the distribution of the psi angle to 180  and the bisecting GlcNAc increases the distribution of the omega angle +60  in the presence of terminal GlcNAcs.	Mannose	76-83	adrenoceptor alpha 1D	Homo sapiens	60-68
29311272-4	2018	Heterologous expression in yeast (Saccharomyces cerevisiae) revealed that STP8 and STP12 catalyze the high-affinity proton-dependent uptake of glucose and also accept galactose and mannose.	Mannose	181-188	sugar transporter protein 12	Arabidopsis thaliana	83-88
29149729-6	2018	The generated Au@cew NPs are mainly encapsulated by ovalbumin, in which the surface is decorated by abundant hybrid mannose and Galbeta(1 4)GlcNAc-terminated glycan ligands.	Mannose	116-123	ovalbumin (SERPINB14)	Gallus gallus	52-61
29273833-1	2018	BACKGROUND: Mannose-binding lectin (MBL) plays an important role in the innate immune response.	Mannose	12-19	mannose binding lectin 2	Homo sapiens	36-39
29434755-5	2018	The monosaccharide composition of ASPS (Arabic candy: Xylose: Glucose: Mannose) was 7.1:22.3:7.6:1.0.	Mannose	71-78	alveolar soft part sarcoma chromosome region, candidate 1 (human)	Mus musculus	34-38
29193802-0	2018	A Synthetic MUC1 Anticancer Vaccine Containing Mannose Ligands for Targeting Macrophages and Dendritic Cells.	Mannose	47-54	mucin 1, cell surface associated	Homo sapiens	12-16
29732051-5	2018	We demonstrated that the albumin nanoparticles modified with dual ligands, a transferrin receptor (TfR)-binding peptide T12 and mannose, efficiently passed through the BBB via the nutrient transporters (i.e., TfR and the albumin-binding receptor SPARC) that were both overexpressed in the BBB and glioma cells, thus achieving biomimetic delivery to glioma.	Mannose	128-135	transferrin receptor	Mus musculus	209-212
29732051-5	2018	We demonstrated that the albumin nanoparticles modified with dual ligands, a transferrin receptor (TfR)-binding peptide T12 and mannose, efficiently passed through the BBB via the nutrient transporters (i.e., TfR and the albumin-binding receptor SPARC) that were both overexpressed in the BBB and glioma cells, thus achieving biomimetic delivery to glioma.	Mannose	128-135	secreted acidic cysteine rich glycoprotein	Mus musculus	246-251
29324290-1	2018	Mannose binding lectin (MBL) generally plays a protective role during viral infection, yet MBL-mediated complement activation promotes Ross River virus (RRV)-induced inflammatory tissue destruction, contributing to arthritis and myositis.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
29220053-5	2018	Unexpectedly, glycation sites (K47, K91 and K135) added by two mannose molecules were identified in glycated beta-Lg with PEF pretreatment.	Mannose	63-70	beta-lactoglobulin	Bos taurus	109-116
29185694-3	2018	PatA catalyzes the transfer of a palmitoyl moiety from palmitoyl-CoA to the 6-position of the mannose ring linked to the 2-position of inositol in PIM1/PIM2.	Mannose	94-101	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	147-151
29185694-3	2018	PatA catalyzes the transfer of a palmitoyl moiety from palmitoyl-CoA to the 6-position of the mannose ring linked to the 2-position of inositol in PIM1/PIM2.	Mannose	94-101	Pim-2 proto-oncogene, serine/threonine kinase	Homo sapiens	152-156
29193802-1	2018	A MUC1 anticancer vaccine equipped with covalently linked divalent mannose ligands was found to improve the antigen uptake and presentation by targeting mannose-receptor-positive macrophages and dendritic cells.	Mannose	67-74	mucin 1, cell surface associated	Homo sapiens	2-6
28973127-8	2017	The X-ray crystallographic structure reveals that two Orysata lectins bind to one biantennary N-glycan (2:1 binding) where one lectin binds to mannose of the alpha1-3 branch, while the other interacts with an N-acetylglucosamine of the alpha1-6 branch.	Mannose	143-150	adrenoceptor alpha 1D	Homo sapiens	158-166
29303997-0	2018	High-Mannose But Not Complex-Type Glycosylation of Tetherin Is Required for Restriction of HIV-1 Release.	Mannose	5-12	bone marrow stromal cell antigen 2	Homo sapiens	51-59
29303997-9	2018	These results demonstrate that high-mannose modification of a single asparagine residue is necessary and sufficient, while complex-type glycosylation is dispensable, for cell-surface tetherin expression and antiviral activity.	Mannose	36-43	bone marrow stromal cell antigen 2	Homo sapiens	183-191
29170125-6	2018	RAW 264.7 cells internalized the SLP-8348 in a process that was mediated by carbohydrate-receptor interactions since it was inhibited by glucose, mannose or EGTA, a Ca+2 chelating agent.	Mannose	146-153	superkiller viralicidic activity 2-like (S. cerevisiae), pseudogene 1	Mus musculus	33-36
29850447-13	2018	Pretreatment of spermatozoa with mannose decreased the effect of Candida spp.	Mannose	33-40	histocompatibility minor 13	Homo sapiens	73-76
29048873-7	2017	Receptors with signaling capability interact with two distinct sets of mycobacterial glycans: targets for dectin-2 overlap with ligands for the mannose-binding endocytic receptors, while mincle binds exclusively to trehalose-containing structures such as trehalose dimycolate.	Mannose	144-151	C-type lectin domain containing 6A	Homo sapiens	106-114
28973127-8	2017	The X-ray crystallographic structure reveals that two Orysata lectins bind to one biantennary N-glycan (2:1 binding) where one lectin binds to mannose of the alpha1-3 branch, while the other interacts with an N-acetylglucosamine of the alpha1-6 branch.	Mannose	143-150	adrenoceptor alpha 1D	Homo sapiens	236-244
28972165-4	2017	We also found that SP-A directly binds the recombinant extracellular domain of EGFR (soluble EGFR or sEGFR), and this binding, unlike that of SP-D, was not blocked by EDTA, excess mannose, or peptide:N-glycosidase F treatment.	Mannose	180-187	surfactant protein A1	Homo sapiens	19-23
29031045-5	2017	We have determined the crystal structure of homogenously glycosylated human IgG3 Fc with a GlcNAc2Man5 (Man5) high mannose glycoform at 1.8A resolution and compared its structural features with published structures from the other IgG subclasses.	Mannose	115-122	immunoglobulin heavy constant gamma 3 (G3m marker)	Homo sapiens	76-80
29119347-0	2017	N-glycan structures and downstream mannose-phosphorylation of plant recombinant human alpha-L-iduronidase: toward development of enzyme replacement therapy for mucopolysaccharidosis I.	Mannose	35-42	alpha-L-iduronidase	Homo sapiens	86-105
29119347-3	2017	Both strategies effectively prevented N-glycan maturation and the resultant N-glycan structures on the consensus sites for N-glycosylation of the human enzyme revealed high-mannose N-glycans of predominantly Man5 (cgl-IDUA) or Man6-8 (gm1-IDUA) structures.	Mannose	173-180	alpha-L-iduronidase	Homo sapiens	218-222
29119347-3	2017	Both strategies effectively prevented N-glycan maturation and the resultant N-glycan structures on the consensus sites for N-glycosylation of the human enzyme revealed high-mannose N-glycans of predominantly Man5 (cgl-IDUA) or Man6-8 (gm1-IDUA) structures.	Mannose	173-180	alpha-L-iduronidase	Homo sapiens	239-243
29119347-5	2017	Because recombinant lysosomal enzymes produced in plants require the addition of mannose-6-phosphate (M6P) in order to be suitable for lysosomal delivery in human cells, we characterized the two IDUA proteins for their amenability to downstream in vitro mannose phosphorylation mediated by a soluble form of the human phosphotransferase (UDP-GlcNAc: lysosomal enzyme N-acetylglucosamine [GlcNAc]-1-phosphotransferase).	Mannose	81-88	alpha-L-iduronidase	Homo sapiens	195-199
29119347-7	2017	This may be due to the greater number of mannose residues comprising the high-mannose N-glycans of gm1-IDUA.	Mannose	41-48	alpha-L-iduronidase	Homo sapiens	99-107
29119347-7	2017	This may be due to the greater number of mannose residues comprising the high-mannose N-glycans of gm1-IDUA.	Mannose	78-85	alpha-L-iduronidase	Homo sapiens	99-107
28640361-7	2017	After validation, the 3 top metabolites (xanthine, hypoxanthine, and d-mannose) were validated: lower levels of xanthine and hypoxanthine and higher levels of d-mannose were found in PLP and CRC cases versus controls.	Mannose	69-78	proteolipid protein 1	Homo sapiens	183-186
28992081-4	2017	Wnt1 was modified with a complex- or hybrid-type glycan at Asn29 and Asn359 and the high-mannose- or hybrid-type glycan at Asn316.	Mannose	89-96	Wnt family member 1	Canis lupus familiaris	0-4
28782625-0	2017	Shifted Golgi targeting of glycosyltransferases and alpha-mannosidase IA from giantin to GM130-GRASP65 results in formation of high mannose N-glycans in aggressive prostate cancer cells.	Mannose	132-139	golgin B1	Homo sapiens	78-85
28782625-0	2017	Shifted Golgi targeting of glycosyltransferases and alpha-mannosidase IA from giantin to GM130-GRASP65 results in formation of high mannose N-glycans in aggressive prostate cancer cells.	Mannose	132-139	golgin A2	Homo sapiens	89-94
28782625-0	2017	Shifted Golgi targeting of glycosyltransferases and alpha-mannosidase IA from giantin to GM130-GRASP65 results in formation of high mannose N-glycans in aggressive prostate cancer cells.	Mannose	132-139	golgi reassembly stacking protein 1	Homo sapiens	95-102
28640361-7	2017	After validation, the 3 top metabolites (xanthine, hypoxanthine, and d-mannose) were validated: lower levels of xanthine and hypoxanthine and higher levels of d-mannose were found in PLP and CRC cases versus controls.	Mannose	159-168	proteolipid protein 1	Homo sapiens	183-186
28994411-3	2017	3.5 and 3.9 A resolution crystal structures of the HIV-1 Env trimer with fully processed and native glycosylation were solved, revealing a glycan shield of high-mannose and complex-type N-glycans that were used to define the complete epitopes of two bNAbs.	Mannose	161-168	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	57-60
28546465-8	2017	We also identified five branched mannose and N-acetylglucosamine glycans at PD-L1 position N192 in all 22 samples.	Mannose	33-40	CD274 molecule	Homo sapiens	76-81
28577071-2	2017	When whole protein extracts from the worms was applied to a series of the columns immobilized with the modified and unmodified mannose-derivatives, respectively, a protein with a molecular weight of 25,000 was isolated by 4-O-methyl mannose-immobilized column chromatography, and termed as a methylated mannose-binding protein (mMBP).	Mannose	127-134	myelin basic protein	Mus musculus	328-332
28577071-3	2017	mMBP bound weakly to a mannose-immobilized column and moderately to a 3-O-methyl mannose-immobilized column.	Mannose	23-30	myelin basic protein	Mus musculus	0-4
28732858-5	2017	STP-1 had a major molecular weight of 190.4kDa, and comprised of arabinose, galactose, glucose, xylose, mannose, galacturonic acid, and glucuronic acid with molar percentages of 1.94, 30.7, 4.54, 23.2, 17.6, 8.11, and 13.9%, respectively.	Mannose	104-111	transition protein 1	Homo sapiens	0-5
29021891-3	2017	However, a team of researchers led by Dr. Wanjun Chen of the National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health (NIH), USA, have recently shown that d-mannose, a naturally occurring C-2 epimer of glucose is likely beneficial to human health.	Mannose	192-201	complement C2	Homo sapiens	225-228
28472687-5	2017	Glycan array analysis of DBL revealed its affinity toward high mannose N-linked glycans with enhanced affinity for terminal mannose including N-linked glycans of HIV envelope glycoprotein gp120 and has strong anti-reverse transcriptase activity.	Mannose	63-70	MCF.2 cell line derived transforming sequence	Homo sapiens	25-28
28800703-4	2017	Dry-state glycation with mannose after ultrasound pretreatment at 0-600 W significantly reduced the IgG and IgE binding of beta-Lg, with the lowest values observed at 400 W. The decrease in the IgG and IgE binding of beta-Lg was attributed to the increase in glycation extent and the changes of secondary and tertiary structure, which reflected in the increase of UV absorbance, alpha-helix and beta-sheet contents, as well as the decrease of intrinsic fluorescence intensity, surface hydrophobicity, beta-turn, and random coil contents.	Mannose	25-32	beta-lactoglobulin	Bos taurus	123-130
28800703-4	2017	Dry-state glycation with mannose after ultrasound pretreatment at 0-600 W significantly reduced the IgG and IgE binding of beta-Lg, with the lowest values observed at 400 W. The decrease in the IgG and IgE binding of beta-Lg was attributed to the increase in glycation extent and the changes of secondary and tertiary structure, which reflected in the increase of UV absorbance, alpha-helix and beta-sheet contents, as well as the decrease of intrinsic fluorescence intensity, surface hydrophobicity, beta-turn, and random coil contents.	Mannose	25-32	beta-lactoglobulin	Bos taurus	217-224
28322582-1	2017	This study aimed to explore the contribution of high-mannose glycans in the masking of conserved V3 crown (GPG) and V2i epitopes on the hypervariable loops of most exposed distal surface of HIV-1 Env.	Mannose	53-60	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	196-199
28412343-2	2017	The monosaccharide component of PAP1-A was L-rhamnose, L-arabinose, L-fucose, D-xylose, D-mannose, D-glucose and D-galactose in the molar ration of 1.82: 1.53: 1.42: 1.31: 5.24: 1: 12.35.	Mannose	88-97	PDGFA associated protein 1	Mus musculus	32-36
28412343-3	2017	The predicted structure of PAP1-A was established to be a complex polysaccharide with a main chain consisted of alpha-(1 4)-linked galactose partially substituted at O-6 position, with the (1 2)-linked xylose, (1 3)-linked arabinose, (1 3)-linked rhamnose, (1 3,6)-linked mannose, and (1 6)-linked mannose, as branches.	Mannose	272-279	PDGFA associated protein 1	Mus musculus	27-31
28759052-1	2017	D-mannose, a C-2 epimer of glucose, exists naturally in many plants and fruits, and is found in human blood at concentrations less than one-fiftieth of that of glucose.	Mannose	0-9	complement C2	Homo sapiens	13-16
28412343-3	2017	The predicted structure of PAP1-A was established to be a complex polysaccharide with a main chain consisted of alpha-(1 4)-linked galactose partially substituted at O-6 position, with the (1 2)-linked xylose, (1 3)-linked arabinose, (1 3)-linked rhamnose, (1 3,6)-linked mannose, and (1 6)-linked mannose, as branches.	Mannose	298-305	PDGFA associated protein 1	Mus musculus	27-31
28692133-7	2017	The final step of membrane disruption by EtpM-enterocin CRL35 is independent from the receptor, which means that the mannose PTS might not be involved in the pore structure.	Mannose	117-124	w0031	Escherichia coli	41-45
28759052-3	2017	Here we show that supraphysiological levels of D-mannose safely achievable by drinking-water supplementation suppressed immunopathology in mouse models of autoimmune diabetes and airway inflammation, and increased the proportion of Foxp3+ regulatory T cells (Treg cells) in mice.	Mannose	47-56	forkhead box P3	Mus musculus	232-237
28652405-4	2017	Competition binding studies indicated that the CRD binds to monosaccharides with modest affinity and that affinity was greatly enhanced for mannose-linked alpha1-2 or alpha1-4 to a second mannose residue.	Mannose	140-147	adrenoceptor alpha 1D	Homo sapiens	167-175
28652405-4	2017	Competition binding studies indicated that the CRD binds to monosaccharides with modest affinity and that affinity was greatly enhanced for mannose-linked alpha1-2 or alpha1-4 to a second mannose residue.	Mannose	188-195	adrenoceptor alpha 1D	Homo sapiens	167-175
28824637-4	2017	These glycans interact with mannose-specific lectins, especially with dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN).	Mannose	28-35	CD209 molecule	Homo sapiens	70-149
28824637-4	2017	These glycans interact with mannose-specific lectins, especially with dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN).	Mannose	28-35	CD209 molecule	Homo sapiens	151-158
28768165-1	2017	Plasma mannose levels are elevated in subjects with insulin resistance independently of obesity.	Mannose	7-14	insulin	Homo sapiens	52-59
28570782-4	2017	The first examples of mannose and biotin ligands coupled to aqueous carboxy-functionalized gold nanoparticles through a spin label are presented.	Mannose	22-29	spindlin 1	Homo sapiens	120-124
28545809-7	2017	We induced CD163 gene in THP-1 and primary human macrophages using polyethylenimine nanoparticles grafted with a mannose ligand (Man-PEI).	Mannose	113-120	CD163 molecule	Homo sapiens	11-16
28602737-1	2017	Mannose-binding lectin (MBL) is a pattern recognition protein that plays an important role in innate immunity capable of activating the lectin pathway of the complement system.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
28575298-6	2017	We found that while the addition of the first mannose unit by Alg1 was successful with all of the LLO molecules, the Alg2-catalyzed reaction was only efficient if the acceptor LLOs contained a sufficiently long lipid tail of four or five isoprenyl units (C20 and C25).	Mannose	46-53	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	62-66
28630087-11	2017	Functionally, the paucimannosidic HNE glycoforms displayed preferential binding to human mannose binding lectin compared with the HNE sialoglycoforms, suggesting a glycoform-dependent involvement of HNE in complement activation.	Mannose	89-96	elastase, neutrophil expressed	Homo sapiens	34-37
28344090-5	2017	The results show that the weight average molecular weight (Mw) of DCP-2 was 2 273Da with a narrow polydispersity index of 1.01, and it was a heteropolysaccharide and consisted of glucose, galactose, arabinose, rhamnose and mannose with a molar ratio of 3.20:2.54:1.69:1.58:1.00.	Mannose	223-230	decapping mRNA 2	Mus musculus	66-71
28509534-8	2017	It was found that Eprex contained the greatest relative abundance of O-acetylated derivatives, Binocrit expressed the least Neu5Gc, and CIGB-EPO showed the greatest variety of high-mannose-phosphate structures.	Mannose	181-188	erythropoietin	Homo sapiens	141-144
28552883-5	2017	We previously showed that ATF6 represents a novel transmembrane-type ERAD-L substrate requiring both EDEM1/2/3-mediated mannose trimming and SEL1L.	Mannose	120-127	activating transcription factor 6 beta	Gallus gallus	26-30
28552883-5	2017	We previously showed that ATF6 represents a novel transmembrane-type ERAD-L substrate requiring both EDEM1/2/3-mediated mannose trimming and SEL1L.	Mannose	120-127	ER degradation enhancing alpha-mannosidase like protein 1	Gallus gallus	101-110
27998032-4	2017	Furthermore, AtGolS3-OE lines possessed higher cellulose and lower lignin contents, an increase in cellulose crystallinity, and significantly altered hemicellulose-derived carbohydrates, notably manifested by their mannose and xylose contents.	Mannose	215-222	galactinol synthase 3	Arabidopsis thaliana	13-20
29171231-5	2017	The results showed that an anti-angiotensin converting enzyme oligosaccharide, GLP-1-1, was obtained from Trichosanthis Pericarpium based on activity tracking, whose average molecular weight was estimated to 1 367; mainly composed of arabinose, mannose, and glucose at a ratio of 0.2:4.3:10.0.	Mannose	245-252	angiotensin I converting enzyme	Homo sapiens	27-61
29171231-5	2017	The results showed that an anti-angiotensin converting enzyme oligosaccharide, GLP-1-1, was obtained from Trichosanthis Pericarpium based on activity tracking, whose average molecular weight was estimated to 1 367; mainly composed of arabinose, mannose, and glucose at a ratio of 0.2:4.3:10.0.	Mannose	245-252	glucagon like peptide 1 receptor	Homo sapiens	79-86
28743912-7	2017	The structures also rationalize the loss of dolichylphosphate mannose synthase function in dpm1-associated CDG.The generation of glycolipid dolichylphosphate mannose (Dol-P-Man) is a critical step for protein glycosylation and GPI anchor synthesis.	Mannose	62-69	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	91-95
28433181-2	2017	The molecular weight of SPS2p showed only one molecular weight distribution (2.6x104Da) and the monosaccharide composition of SPS2p showed the presence of arabinose, mannose, glucose and galactose at the ratio of 1.31:1.00:3.59:1.59.	Mannose	166-173	selenophosphate synthetase 2	Homo sapiens	126-131
28654657-11	2017	But when GALE was knocked out in tandem with GALK1, N-glycans were exclusively of the high mannose type.	Mannose	91-98	UDP-galactose-4-epimerase	Homo sapiens	9-13
28143661-11	2017	Significant differences were found in both the ascitic and serum levels of amylase and lipase between the untreated rats and the rats treated with adipose-derived stem cell sheets with mannose (P &lt; .05).	Mannose	185-192	lipase G, endothelial type	Rattus norvegicus	87-93
28371030-1	2017	Within the endoplasmic reticulum, immature glycoproteins are sorted into secretion and degradation pathways through the sequential trimming of mannose residues from Man9 GlcNAc2 to Man5 GlcNAc2 by the combined actions of assorted alpha-1,2-mannosidases.	Mannose	143-150	mannosidase alpha class 1A member 1	Homo sapiens	165-169
28143661-12	2017	Fibroblast growth factor 2 gene expression levels were greater in human adipose-derived stem cells treated with mannose than in human adipose-derived stem cells treated without mannose.	Mannose	112-119	fibroblast growth factor 2	Homo sapiens	0-26
28143661-12	2017	Fibroblast growth factor 2 gene expression levels were greater in human adipose-derived stem cells treated with mannose than in human adipose-derived stem cells treated without mannose.	Mannose	177-184	fibroblast growth factor 2	Homo sapiens	0-26
28143661-14	2017	The enhancing effect of mannose on the function of adipose-derived stem cells may be partially explained by induction of fibroblast growth factor 2.	Mannose	24-31	fibroblast growth factor 2	Rattus norvegicus	121-147
28363873-0	2017	Production of recombinant human acid alpha-glucosidase with high-mannose glycans in gnt1 rice for the treatment of Pompe disease.	Mannose	65-72	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	84-88
28385528-0	2017	Mannose-conjugated platinum complexes reveals effective tumor targeting mediated by glucose transporter 1.	Mannose	0-7	solute carrier family 2 member 1	Homo sapiens	84-105
28325338-5	2017	PCS2 was composed of d-galactose, d-mannose, d-(+)-glucose, d-(+)-xylose, l-arabinose and l-rhamnose.	Mannose	34-43	dominant cataract 4	Mus musculus	0-4
28534482-3	2017	We show that Fbs1 is able to bind diverse types of N-linked glycomolecules; however, wild-type Fbs1 preferentially binds high-mannose-containing glycans.	Mannose	126-133	fibrosin	Homo sapiens	13-17
28534482-3	2017	We show that Fbs1 is able to bind diverse types of N-linked glycomolecules; however, wild-type Fbs1 preferentially binds high-mannose-containing glycans.	Mannose	126-133	fibrosin	Homo sapiens	95-99
28363873-11	2017	N-glycan analysis revealed the presence of high-mannose N-glycans on gnt1-GAA.	Mannose	48-55	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	69-73
28363873-12	2017	In addition, the production of high-mannose GAA using gnt1 rice calli as an expression host was characterized, which may aid the future development of therapeutic enzymes for the treatment of Pompe disease.	Mannose	36-43	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	54-58
32263681-5	2017	Through the specific recognition between carbohydrates and glycoproteins in cell membranes, these TMV based vectors show specificity in different cell lines: in the galectin-rich MCF-7 cell line, CDDP@TMV-Man shows enhanced endocytosis and apoptosis efficiency; in the asialoglycoprotein receptor (ASGPR)-overexpressing HepG2 cell line, CDDP@TMV-Lac shows superiority in endocytosis and apoptosis.	Mannose	205-208	asialoglycoprotein receptor 1	Homo sapiens	298-303
28418238-2	2017	The resulting polymers were shown, via multichannel surface plasmon resonance, to interact specifically with human macrophage galactose lectin (MGL; CD301) with high affinity (KD = 1.11 muM), but they did not bind to the mannose/fucose-selective human lectin dendritic-cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN; CD209).	Mannose	221-228	C-type lectin domain containing 10A	Homo sapiens	144-147
28540182-0	2017	Mannose-Binding Lectin (MBL) gene polymorphisms in susceptibility to pulmonary tuberculosis among the Lur population of Lorestan Province of Iran.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
28540182-4	2017	The aim of this study was to investigate mannose-binding lectin (MBL) gene polymorphisms with susceptibility to pulmonary tuberculosis (PTB) in a Lur population of Iran.	Mannose	41-48	mannose binding lectin 2	Homo sapiens	65-68
28264906-3	2017	A gene-regulatory function was revealed in Escherichia coli expressing plasmid-borne NMB0419 and showing significantly increased epithelial adherence compared to the wild type, due to increased expression of mannose-sensitive type 1 pili.	Mannose	208-215	transcriptional regulator	Neisseria meningitidis MC58	85-92
28348411-7	2017	We find that most glycosites in recombinant Env trimers are fully occupied by glycans, varying in the proportion of high-mannose/hybrid and complex-type glycans.	Mannose	121-128	endogenous retrovirus group K member 20	Homo sapiens	44-47
28425428-2	2017	Mannose-binding lectin (MBL), an innate immune protein, could play an important role in the innate response of channel catfish by binding to CCV.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
28251761-8	2017	Mannose residue binds to POMK mainly via the hydroxyl group at C2-position, differentiating from other monosaccharide residues.	Mannose	0-7	protein O-mannose kinase	Homo sapiens	25-29
27165013-4	2017	In vitro surface plasmon resonance assay indicated that Polyman9 dose-dependently inhibits the binding to immobilized mannose residues of plasma mannose-binding lectin-C selectively over that of mannose-binding lectin-A.	Mannose	118-125	mannose-binding lectin (protein C) 2	Mus musculus	145-169
28249163-7	2017	Thus, HIV-1 Env vaccination induced mannose-dependent antibodies with characteristics of V3-glycan bnAb precursors.	Mannose	36-43	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	12-15
28098871-3	2017	The lectin PCL is a mannose binding lectin which induces tumor cell apoptosis and autophagy.	Mannose	20-27	fms related receptor tyrosine kinase 4	Homo sapiens	11-14
28207759-3	2017	Supplementing storage cells with lacking enzyme is accomplished via chronic intravenous administration of recombinant GBA containing mannose-terminated N-linked glycans, mediating the selective uptake by macrophages expressing mannose-binding lectin(s).	Mannose	133-140	glucosylceramidase beta	Homo sapiens	118-121
28207759-3	2017	Supplementing storage cells with lacking enzyme is accomplished via chronic intravenous administration of recombinant GBA containing mannose-terminated N-linked glycans, mediating the selective uptake by macrophages expressing mannose-binding lectin(s).	Mannose	133-140	mannose binding lectin 2	Homo sapiens	227-249
28029038-7	2017	This multiplex cytosensor was further applied for simultaneous quantitative evaluation of the expression levels of mannose and EGFR on MCF-7 cells, revealed that the average numbers of mannose and EGFR per captured MCF-7 cell were 1.2 x 106 and 0.86 x 105 with the relative standard deviation of 5.3% and 4.2%, respectively.	Mannose	115-122	epidermal growth factor receptor	Homo sapiens	197-201
28117590-4	2017	In this study, structural characterization revealed that MC-2 has an average molecular weight of 9.83 kDa and is composed of arabinose (20.9%), mannose (4.5%), glucose (71.9%), and galactose (2.7%).	Mannose	144-151	melanocortin 5 receptor	Homo sapiens	57-61
28011641-6	2017	Here we report the structure of the lectin and EGF domains of L-selectin bound to a fucose mimetic; that is, a terminal mannose on an N-glycan attached to a symmetry-related molecule.	Mannose	120-127	selectin L	Homo sapiens	62-72
28031338-8	2017	Intriguingly, following CLP, Nlrp3-/- peritoneal cells (primarily neutrophils) demonstrate decreased autophagy, augmented phagocytosis, and enhanced scavenger receptor (macrophage receptor with collagenous structure) and mannose-binding leptin expression.	Mannose	221-228	NLR family, pyrin domain containing 3	Mus musculus	29-34
28722428-4	2017	SPR measurements show that the BSA-mannose conjugate with 11 mannoses exhibit the highest affinity to the lectin concanavalin A with a limit of detection of ca.	Mannose	35-42	sepiapterin reductase	Homo sapiens	0-3
28722428-4	2017	SPR measurements show that the BSA-mannose conjugate with 11 mannoses exhibit the highest affinity to the lectin concanavalin A with a limit of detection of ca.	Mannose	61-69	sepiapterin reductase	Homo sapiens	0-3
28029038-7	2017	This multiplex cytosensor was further applied for simultaneous quantitative evaluation of the expression levels of mannose and EGFR on MCF-7 cells, revealed that the average numbers of mannose and EGFR per captured MCF-7 cell were 1.2 x 106 and 0.86 x 105 with the relative standard deviation of 5.3% and 4.2%, respectively.	Mannose	185-192	epidermal growth factor receptor	Homo sapiens	127-131
27863995-2	2017	We have previously developed a potent mannose-modified lipid calcium phosphate (LCP) nanoparticle (NP)-based Trp2 vaccine for melanoma therapy, but because this vaccine can induce a potent anti-tumor immune response only during the early stages of melanoma, poor tumor growth inhibition has been observed in more advanced melanoma models, likely due to the development of an immune-suppressive tumor microenvironment (TME).	Mannose	38-45	tRNA proline 2	Mus musculus	109-113
28046067-4	2017	This activity was inhibited by an excessive amount of mannose, and by the mutation of mannose-binding motif in Dectin-2.	Mannose	54-61	C-type lectin domain containing 6A	Homo sapiens	111-119
27688191-9	2017	The results from this study demonstrate the usefulness of glucose, mannose and galactose as alternative sugar motif on glycoconjugation for GLUT mediated drug design and pharmaceutical R&amp;D, and the obtained fundamental results also support the potential of the GLUT targeted platinum(II)-sugar conjugates as lead compounds for further pre-clinical evaluation.	Mannose	67-74	solute carrier family 2 member 1	Homo sapiens	140-144
27688191-9	2017	The results from this study demonstrate the usefulness of glucose, mannose and galactose as alternative sugar motif on glycoconjugation for GLUT mediated drug design and pharmaceutical R&amp;D, and the obtained fundamental results also support the potential of the GLUT targeted platinum(II)-sugar conjugates as lead compounds for further pre-clinical evaluation.	Mannose	67-74	solute carrier family 2 member 1	Homo sapiens	265-269
28086930-5	2017	METHODS: We investigated mannose-binding lectin-associated serine protease (MASP-2) levels in cerebrospinal fluid (CSF) samples derived from the diagnostic lumbar puncture, which was available for 307 of 792 pneumococcal meningitis episodes included in our prospective nationwide cohort study (39%), and the association between these levels and clinical outcome.	Mannose	25-32	mannan-binding lectin serine peptidase 2	Mus musculus	76-82
28046067-4	2017	This activity was inhibited by an excessive amount of mannose, and by the mutation of mannose-binding motif in Dectin-2.	Mannose	86-93	C-type lectin domain containing 6A	Homo sapiens	111-119
28046067-7	2017	Our study suggests that a glycosylated protein with mannose-related structure is recognized by Dectin-2.	Mannose	52-59	C-type lectin domain containing 6A	Homo sapiens	95-103
27670784-2	2017	Yeast ALG1 (asparagine-linked glycosylation 1) encodes a beta-1, 4 mannosyltransferase that adds the first mannose onto GlcNAc2-PP-Dol to produce a core trisaccharide Man1GlcNAc2-PP-Dol.	Mannose	107-114	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	6-10
27670784-2	2017	Yeast ALG1 (asparagine-linked glycosylation 1) encodes a beta-1, 4 mannosyltransferase that adds the first mannose onto GlcNAc2-PP-Dol to produce a core trisaccharide Man1GlcNAc2-PP-Dol.	Mannose	107-114	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	12-45
27871371-5	2017	In addition, DM1 synthesized much higher amounts of mannose-containing disaccharide trehalose analog (Man-TA) than did the WT and DM2.	Mannose	52-59	immunoglobulin heavy diversity 1-7	Homo sapiens	13-16
28042344-2	2017	We synthesized 68Ga-2-(p-isothiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid (NOTA) mannosylated human serum albumin (MSA) by conjugating human serum albumin with mannose, followed by conjugation with NOTA and labeling it with 68Ga.	Mannose	178-185	albumin	Rattus norvegicus	118-131
27871117-2	2017	SCP-80-I is composed mainly of arabinose, mannose, glucose, and galactose in a molar ratio of 0.369:0.824:10.759:0.333, and has a molecular mass of 18350 Da and beta-glycosides linkages in its molecular structure.	Mannose	42-49	cysteine-rich secretory protein 3	Rattus norvegicus	0-3
27934478-1	2016	Surfactant protein A (SP-A), a lung anti-infective protein, is a lectin with affinity for sugars found on fungal and micrococcal surfaces such as mannose.	Mannose	146-153	surfactant protein A1	Homo sapiens	0-20
27997616-3	2016	Gas chromatography analysis indicated that UP2 contained three kinds of monosaccharides, including mannose, glucose, and galactose at a molar ratio of 1.7:1.0:1.2.	Mannose	99-106	uroplakin 2	Mus musculus	43-46
27934478-1	2016	Surfactant protein A (SP-A), a lung anti-infective protein, is a lectin with affinity for sugars found on fungal and micrococcal surfaces such as mannose.	Mannose	146-153	surfactant protein A1	Homo sapiens	22-26
27934478-4	2016	The presence of mannose on the surface was demonstrated by zeta potential changes according to pH and by a strong aggregation in the presence of concanavalin A. Mannosylated nanoparticles bound to SP-A as demonstrated by dynamic light scattering and transmission electron microscopy.	Mannose	16-23	surfactant protein A1	Homo sapiens	197-201
27788491-0	2016	Pseudomonas aeruginosa-mannose-sensitive hemagglutinin inhibits pancreatic cancer cell proliferation and induces apoptosis via the EGFR pathway and caspase signaling.	Mannose	23-30	epidermal growth factor receptor	Homo sapiens	131-135
27053576-6	2016	By microarray analyses, we show that the C-type lectin receptor DC-SIGNR, like the closely related DC-SIGN we investigated earlier, binds to the beta1,2-gluco-oligosaccharides, as does the soluble immune effector serum mannose-binding protein.	Mannose	219-226	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	145-152
27669574-2	2016	Each binds to high-mannose glycans on the surface envelope glycoprotein gp120, yet the mechanisms by which they engage viral spikes and exhibit inhibition constants ranging from nanomolar to picomolar are not understood.	Mannose	19-26	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	72-77
27782318-1	2016	Mannose-binding lectin (MBL)-associated serine proteases (MASPs) are the enzymatic constituents of the lectin pathway of the complement system.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
26457920-3	2016	Accurate identification of mannose-interacting residues (MIR) may provide important clues to decipher the underlying mechanisms of protein-mannose interactions during infections.	Mannose	27-34	MLX interacting protein	Homo sapiens	57-60
27617431-3	2016	We present 3.5-A- and 3.9-A-resolution crystal structures of the HIV-1 Env trimer with fully processed and native glycosylation, revealing a glycan shield of high-mannose and complex-type N-glycans, which we used to define complete epitopes of two bNAbs.	Mannose	163-170	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	71-74
27378476-2	2016	Here we tested whether the mannose-binding lectin (MBL2), an initiating factor of lectin complement pathway activation, plays a crucial role in STEC HUS.	Mannose	27-34	mannose-binding lectin (protein C) 2	Mus musculus	51-55
28251047-6	2017	Moreover, PNSDS with mannose targeting moieties can selectively accumulate in mice liver, induce specific inhibition of macrophage TNF-alpha expression in vivo, and consequently protect mice from inflammation-induced liver damages.	Mannose	21-28	tumor necrosis factor	Mus musculus	131-140
27585546-5	2016	Mannose-binding lectin (MBL), a recognition subunit, binds to arrays of carbohydrates on the surfaces of pathogens, which results in the activation of MBL-associated serine protease-2 to trigger a downstream reaction cascade of complement system.	Mannose	0-7	MBL associated serine protease 2	Homo sapiens	151-183
27448056-0	2016	Biomarkers: Mannose levels predict insulin resistance.	Mannose	12-19	insulin	Homo sapiens	35-42
27193255-2	2016	Mannanase is an important enzyme that hydrolyses mannose-containing polysaccharides which are abundant in plants.	Mannose	49-56	mannosidase beta	Homo sapiens	0-9
27241848-3	2016	The GNPTAB gene products (the alpha and ss subunits) are responsible for recognition and catalysis of hydrolases whereas the GNPTG gene product (the gamma subunit) enhances mannose phosphorylation of a subset of hydrolases.	Mannose	173-180	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta	Danio rerio	4-10
27241848-3	2016	The GNPTAB gene products (the alpha and ss subunits) are responsible for recognition and catalysis of hydrolases whereas the GNPTG gene product (the gamma subunit) enhances mannose phosphorylation of a subset of hydrolases.	Mannose	173-180	N-acetylglucosamine-1-phosphate transferase subunit gamma	Danio rerio	125-130
27241848-4	2016	Here we identify and characterize a zebrafish gnptg insertional mutant and show that loss of the gamma subunit reduces mannose phosphorylation on a subset glycosidases but does not affect modification of several cathepsin proteases.	Mannose	119-126	N-acetylglucosamine-1-phosphate transferase subunit gamma	Danio rerio	46-51
27373800-4	2016	The mannose substituted Pt(iv) complexes A4 and A5 were also over an order of magnitude more potent towards HeLa, A549, MCF-7 and PC3 than cisplatin and oxaliplatin.	Mannose	4-11	chromobox 8	Homo sapiens	130-133
27557564-1	2016	The innate immunity gene mannose-binding lectin2 (MBL2) has played an important role in hepatitis B virus (HBV) infection, and the relationship between MBL2 variants and hepatocellular carcinoma (HCC) risk has not yet been identified.	Mannose	25-32	mannose binding lectin 2	Homo sapiens	50-54
27557564-1	2016	The innate immunity gene mannose-binding lectin2 (MBL2) has played an important role in hepatitis B virus (HBV) infection, and the relationship between MBL2 variants and hepatocellular carcinoma (HCC) risk has not yet been identified.	Mannose	25-32	mannose binding lectin 2	Homo sapiens	152-156
27525949-7	2016	The putative P. integrifolia lectin protein (PIA) contained three mannose-binding sites.	Mannose	66-73	RPTOR independent companion of MTOR complex 2	Homo sapiens	45-48
27525949-8	2016	The agglutinating activity exhibited by PIA was inhibited by D-mannose.	Mannose	61-70	RPTOR independent companion of MTOR complex 2	Homo sapiens	40-43
26969323-6	2016	The assay measures the inhibitor"s ability to interfere with the binding of murine MBL-A or MBL-C, or of human recombinant MBL, to mannose residues immobilized on the sensor chip surface.	Mannose	131-138	mannose-binding lectin (protein A) 1	Mus musculus	83-88
26969323-6	2016	The assay measures the inhibitor"s ability to interfere with the binding of murine MBL-A or MBL-C, or of human recombinant MBL, to mannose residues immobilized on the sensor chip surface.	Mannose	131-138	mannose-binding lectin (protein C) 2	Mus musculus	92-97
26969323-6	2016	The assay measures the inhibitor"s ability to interfere with the binding of murine MBL-A or MBL-C, or of human recombinant MBL, to mannose residues immobilized on the sensor chip surface.	Mannose	131-138	mannose binding lectin 2	Homo sapiens	83-86
27345527-2	2016	Physicochemical characterization indicated that POP1 had a relative molecular weight of 8.10 x 10(3) Da and consisted of rhamnose (5.74%), arabinose (12.58%), mannose (10.97%), glucose (64.96%), and galactose (6.55%).	Mannose	159-166	POP1 homolog, ribonuclease P/MRP subunit	Homo sapiens	48-52
27438765-1	2016	The dense patch of high-mannose-type glycans surrounding the N332 glycan on the HIV envelope glycoprotein (Env) is targeted by multiple broadly neutralizing antibodies (bnAbs).	Mannose	24-31	endogenous retrovirus group K member 20	Homo sapiens	84-105
27438765-1	2016	The dense patch of high-mannose-type glycans surrounding the N332 glycan on the HIV envelope glycoprotein (Env) is targeted by multiple broadly neutralizing antibodies (bnAbs).	Mannose	24-31	endogenous retrovirus group K member 20	Homo sapiens	107-110
27206797-0	2016	Pseudomonas aeruginosa mannose-sensitive hemagglutinin inhibits proliferation and invasion via the PTEN/AKT pathway in HeLa cells.	Mannose	23-30	phosphatase and tensin homolog	Homo sapiens	99-103
27345421-0	2016	Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance.	Mannose	66-73	insulin	Homo sapiens	85-92
27345421-4	2016	We observed significant correlations between plasma mannose levels, BMI, and insulin resistance (IR).	Mannose	52-59	insulin	Homo sapiens	77-84
26075587-7	2016	alpha2M molecules isolated from sera of CC patients have higher content of alpha2,6 sialic acid, N-acetylglucosamine and mannose residues, and tri-/tetraantennary complex type high-mannose N-glycans.	Mannose	121-128	alpha-2-macroglobulin	Homo sapiens	0-7
26075587-7	2016	alpha2M molecules isolated from sera of CC patients have higher content of alpha2,6 sialic acid, N-acetylglucosamine and mannose residues, and tri-/tetraantennary complex type high-mannose N-glycans.	Mannose	181-188	alpha-2-macroglobulin	Homo sapiens	0-7
27350617-7	2016	In addition, compared to adhesion to IPEC-J2 cells, adhesion to mucin by both LM1 and LGG was characterized by enhanced specific recognition of glycoreceptor components such as galactose, mannose, and N-acetylglucosamine.	Mannose	188-195	lymphomyeloid antigen 1	Mus musculus	78-81
27404661-4	2016	The results show that the MBL2 variant rs5030737 at codon 52 was associated with a low level of mannose-binding lectin and impaired mannose-binding lectin-mannose-associated serine protease (MBL-MASP) functional activity in Crohn"s disease patients.	Mannose	96-103	mannose binding lectin 2	Homo sapiens	26-30
27404661-4	2016	The results show that the MBL2 variant rs5030737 at codon 52 was associated with a low level of mannose-binding lectin and impaired mannose-binding lectin-mannose-associated serine protease (MBL-MASP) functional activity in Crohn"s disease patients.	Mannose	96-103	mannose binding lectin 2	Homo sapiens	26-29
27404661-4	2016	The results show that the MBL2 variant rs5030737 at codon 52 was associated with a low level of mannose-binding lectin and impaired mannose-binding lectin-mannose-associated serine protease (MBL-MASP) functional activity in Crohn"s disease patients.	Mannose	132-139	mannose binding lectin 2	Homo sapiens	26-30
27404661-4	2016	The results show that the MBL2 variant rs5030737 at codon 52 was associated with a low level of mannose-binding lectin and impaired mannose-binding lectin-mannose-associated serine protease (MBL-MASP) functional activity in Crohn"s disease patients.	Mannose	132-139	mannose binding lectin 2	Homo sapiens	26-29
26931382-2	2016	ALG1 encodes a beta1,4 mannosyltransferase that catalyzes the addition of the first of nine mannose moieties to form a dolichol-lipid linked oligosaccharide intermediate required for proper N-linked glycosylation.	Mannose	92-99	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	0-4
26867733-4	2016	Notably, the affinity of CRLL-N was most potent to one of three Man 8 glycans and Man 9 glycan, whereas the affinity of CRLL-C decreased with the increase in the number of extended alpha1-2 linked mannose residue.	Mannose	197-204	adrenoceptor alpha 1D	Homo sapiens	181-189
27206797-0	2016	Pseudomonas aeruginosa mannose-sensitive hemagglutinin inhibits proliferation and invasion via the PTEN/AKT pathway in HeLa cells.	Mannose	23-30	AKT serine/threonine kinase 1	Homo sapiens	104-107
27157141-4	2016	RNA interference (RNAi) of SlDof22 in transgenic lines induced AsA levels, and affected the expression of genes in the D-mannose/L-galactose pathway and AsA recycling.	Mannose	119-128	Dof zinc finger protein 22	Solanum lycopersicum	27-34
27099319-5	2016	Our results show that high-mannose-type and single-GlcNAc-type N-glycans, but not complex-type N-glycans, are capable of inducing more active hIL12 p40, hIL12 p70, and hIL-10 production in human DCs.	Mannose	27-34	interleukin 9	Homo sapiens	148-151
27099319-5	2016	Our results show that high-mannose-type and single-GlcNAc-type N-glycans, but not complex-type N-glycans, are capable of inducing more active hIL12 p40, hIL12 p70, and hIL-10 production in human DCs.	Mannose	27-34	annexin A6	Homo sapiens	159-162
27053713-1	2016	The most common congenital disorder of glycosylation (CDG), phosphomannomutase 2 (PMM2)-CDG, is caused by mutations in PMM2 that limit availability of mannose precursors required for protein N-glycosylation.	Mannose	151-158	phosphomannomutase 2	Homo sapiens	60-80
27099319-6	2016	Significantly higher HLA-DR, CD40, CD83, and CD86 expression levels, as well reduced endocytotic capacity in human DCs, were noted in the high-mannose-type rH1HA and single-GlcNAc-type rH1HA groups than in the complex-type N-glycan rH1HA group.	Mannose	143-150	CD40 molecule	Homo sapiens	29-33
27099319-6	2016	Significantly higher HLA-DR, CD40, CD83, and CD86 expression levels, as well reduced endocytotic capacity in human DCs, were noted in the high-mannose-type rH1HA and single-GlcNAc-type rH1HA groups than in the complex-type N-glycan rH1HA group.	Mannose	143-150	CD83 molecule	Homo sapiens	35-39
27099319-6	2016	Significantly higher HLA-DR, CD40, CD83, and CD86 expression levels, as well reduced endocytotic capacity in human DCs, were noted in the high-mannose-type rH1HA and single-GlcNAc-type rH1HA groups than in the complex-type N-glycan rH1HA group.	Mannose	143-150	CD86 molecule	Homo sapiens	45-49
27151646-3	2016	METHODS: Gene and protein expression of ICAM-1 in primary BRECs cultured in medium containing increasing concentrations of mannose or glucose in the presence or absence of tunicamycin were studied with reverse transcription-polymerase chain reaction and Western blot analysis, and the expression level of ICAM-1 at the surface of BRECs was examined with an immunofluorescence analysis.	Mannose	123-130	intercellular adhesion molecule 1	Bos taurus	40-46
27053713-1	2016	The most common congenital disorder of glycosylation (CDG), phosphomannomutase 2 (PMM2)-CDG, is caused by mutations in PMM2 that limit availability of mannose precursors required for protein N-glycosylation.	Mannose	151-158	phosphomannomutase 2	Homo sapiens	82-86
27053713-1	2016	The most common congenital disorder of glycosylation (CDG), phosphomannomutase 2 (PMM2)-CDG, is caused by mutations in PMM2 that limit availability of mannose precursors required for protein N-glycosylation.	Mannose	151-158	phosphomannomutase 2	Homo sapiens	119-123
26638121-3	2016	The hemagglutinating activity of AAL was maintained after incubation at a wide range of temperature (40 to 70  C) and pH, was shown to be dependent on divalent cations, and was inhibited by d-mannose and d-sucrose.	Mannose	190-199	active avoidance learning	Mus musculus	33-36
26638121-7	2016	In the formalin test, AAL (0.1 mg/kg) inhibited by 48% the licking time in the inflammatory phase, an effect that was recovered by the lectin association with mannose.	Mannose	159-166	active avoidance learning	Mus musculus	22-25
27250970-5	2016	SP-A and SP-D bind glucan and mannose residues from fungal cell wall, but there is still a lack of information on their binding to other fungal carbohydrate residues.	Mannose	30-37	surfactant protein A1	Homo sapiens	0-4
27250970-5	2016	SP-A and SP-D bind glucan and mannose residues from fungal cell wall, but there is still a lack of information on their binding to other fungal carbohydrate residues.	Mannose	30-37	surfactant protein D	Homo sapiens	9-13
27008861-0	2016	Mammalian alpha-1,6-Fucosyltransferase (FUT8) Is the Sole Enzyme Responsible for the N-Acetylglucosaminyltransferase I-independent Core Fucosylation of High-mannose N-Glycans.	Mannose	157-164	fucosyltransferase 8	Homo sapiens	10-38
27240337-3	2016	Locust bean gum (LBG) is a polysaccharide composed of galactose and mannose residues, which may favour specific recognition by macrophages and potentiate phagocytosis.	Mannose	68-75	brain expressed associated with NEDD4 1	Homo sapiens	7-11
27008861-0	2016	Mammalian alpha-1,6-Fucosyltransferase (FUT8) Is the Sole Enzyme Responsible for the N-Acetylglucosaminyltransferase I-independent Core Fucosylation of High-mannose N-Glycans.	Mannose	157-164	fucosyltransferase 8	Homo sapiens	40-44
27008861-7	2016	The production of the homogeneous core-fucosylated Man5GlcNAc2 glycoform of EPO in the FUT8-overexpressed HEK293S GnT I(-/-) cell line represents the first example of production of fully core-fucosylated high-mannose glycoforms.	Mannose	209-216	erythropoietin	Homo sapiens	76-79
27048414-2	2016	Surface-adsorbed salivary agglutinin (SAG) activates the lectin pathway (LP) of the complement system via mannose-binding lectin, while SAG in solution inhibits complement activation.	Mannose	106-113	deleted in malignant brain tumors 1	Homo sapiens	17-36
27192579-0	2016	Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.	Mannose	129-136	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	120-123
27192579-1	2016	The high-mannose patch on HIV Env is a preferred target for broadly neutralizing antibodies (bnAbs), but to date, no vaccination regimen has elicited bnAbs against this region.	Mannose	9-16	endogenous retrovirus group K member 20	Homo sapiens	30-33
26872155-8	2016	The PNGase F coated magnetic beads offered comparable deglycosylation level to the conventional in-solution based method in 10-min reaction times for the model glycoproteins of immunoglobulin G (mostly neutral carbohydrates), ribonuclease B (high mannose type sugars), and fetuin (highly sialylated oligosaccharides) with the special features of easy removal of the enzyme from the reaction mixture and reusability.	Mannose	247-254	N-glycanase 1	Homo sapiens	4-10
27048414-2	2016	Surface-adsorbed salivary agglutinin (SAG) activates the lectin pathway (LP) of the complement system via mannose-binding lectin, while SAG in solution inhibits complement activation.	Mannose	106-113	deleted in malignant brain tumors 1	Homo sapiens	38-41
26442658-1	2016	Mannose-binding lectin (MBL) is a soluble lectin of the innate immune system that is produced by the liver and secreted into the circulation where it activates the lectin complement pathway, enhances phagocytosis of microorganisms by leukocytes, and modulates inflammation.	Mannose	0-7	mannose-binding lectin (protein C) 2	Mus musculus	24-27
26785728-7	2016	By multiplexed capillary gel electrophoresis coupled to laser induced fluorescence detection (xCGE-LIF) we could show that PMM2-iPSC-C3 exhibit the common hPSC N-glycosylation pattern with high-mannose-type N-glycans as the predominant species.	Mannose	194-201	phosphomannomutase 2	Homo sapiens	123-127
26996948-9	2016	PIGG is the enzyme that modifies the second mannose with ethanolamine phosphate, which is removed soon after GPI is attached to the protein.	Mannose	44-51	phosphatidylinositol glycan anchor biosynthesis class G	Homo sapiens	0-4
26773807-6	2016	By using Man9 GlcNAc2 -BODIPY as a cargo compound, the carrier protein was also delivered into the ER with concomitant processing of mannose to Man5,6, by the ER-resident alpha1,2-mannosidase.	Mannose	133-140	mannosidase alpha class 1A member 1	Homo sapiens	9-13
26773807-6	2016	By using Man9 GlcNAc2 -BODIPY as a cargo compound, the carrier protein was also delivered into the ER with concomitant processing of mannose to Man5,6, by the ER-resident alpha1,2-mannosidase.	Mannose	133-140	mannosidase alpha class 1A member 2	Homo sapiens	171-191
26735314-5	2016	Uptake studies performed on F4/80(+) and CD11c(+) cells showed significant uptake and/or binding for lipopeptides containing mannose, and also the lipopeptide without mannose when compared to the control peptides (peptide with no lipid and peptide with no mannose and no lipid).	Mannose	125-132	integrin subunit alpha X	Homo sapiens	41-46
26696414-1	2016	Antagonists of mannose binding lectin (MBL) have shown a protective role against brain reperfusion damage after acute ischemic stroke.	Mannose	15-22	mannose-binding lectin (protein C) 2	Mus musculus	39-42
26985831-11	2016	Modification of the complex heterotrimeric pili of a model probiotic and microbiota isolate with mannose and fucose is of importance for the functional interaction with the host immune lectin receptor DC-SIGN on human dendritic cells.	Mannose	97-104	CD209 molecule	Homo sapiens	201-208
26965057-3	2016	The enzyme transfers a palmitoyl moiety from palmitoyl-CoA to the 6-position of the mannose ring linked to 2-position of inositol in PIM1/PIM2.	Mannose	84-91	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	133-137
26965057-3	2016	The enzyme transfers a palmitoyl moiety from palmitoyl-CoA to the 6-position of the mannose ring linked to 2-position of inositol in PIM1/PIM2.	Mannose	84-91	Pim-2 proto-oncogene, serine/threonine kinase	Homo sapiens	138-142
26787888-6	2016	Specifically, production of IFN-gamma on stimulation of dectin-1, mannose, and Toll-like receptors with Candida albicans and Staphylococcus epidermidis was 2.5- and 2.9-fold higher in high-risk subjects than in low-risk subjects, respectively (P = 0.007 and P = 0.01).	Mannose	66-73	interferon gamma	Homo sapiens	28-37
26932667-3	2016	A mutant variant of mannose binding Allium sativum leaf agglutinin (mASAL) was previously reported to exhibit strong antifungal activity against R. solani.	Mannose	20-27	argininosuccinate lyase	Mus musculus	68-73
26850110-0	2016	High mannose-binding Pseudomonas fluorescens lectin (PFL) downregulates cell surface integrin/EGFR and induces autophagy in gastric cancer cells.	Mannose	5-12	epidermal growth factor receptor	Homo sapiens	94-98
26822404-9	2016	Complementation assays and glycan analysis in yeast alg3 mutant confirmed the reduced enzymatic function of the proteins encoded by the cce2/cce3 alleles - leading to accumulation of M5(ER), the immature five mannose-containing oligosaccharide structure found in the ER.	Mannose	209-216	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	52-56
26837192-1	2016	BACKGROUND: Broadly neutralizing antibodies (bnAbs) directed against the mannose-patch on the HIV envelope glycoprotein gp120 have several features that make them desirable targets for vaccine design.	Mannose	73-80	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	120-125
26503547-4	2016	Single crystal X-ray diffraction analysis to 2.7 A resolution of Fv M6P-1 in complex with Man6P reveals that specificity and affinity is achieved via multiple hydrogen bonds to the mannose ring and two salt bridges to the phosphate moiety.	Mannose	181-188	trophoblast glycoprotein	Homo sapiens	68-73
26580315-0	2016	STD NMR and molecular modelling insights into interaction of novel mannose-based ligands with DC-SIGN.	Mannose	67-74	CD209 molecule	Homo sapiens	94-101
26580315-1	2016	Study of interaction of mannose-based ligands with receptor DC-SIGN using high resolution NMR in combination with molecular modelling showed that four alpha-d-mannoside ligands interact with the binding site predominantly through the mannose moiety.	Mannose	24-31	CD209 molecule	Homo sapiens	60-67
26580315-1	2016	Study of interaction of mannose-based ligands with receptor DC-SIGN using high resolution NMR in combination with molecular modelling showed that four alpha-d-mannoside ligands interact with the binding site predominantly through the mannose moiety.	Mannose	234-241	CD209 molecule	Homo sapiens	60-67
26667170-0	2016	Mannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Induces CD4+ T Cell Anergy via GRAIL.	Mannose	0-7	CD4 molecule	Homo sapiens	73-76
26663535-6	2016	We found that the HexNAc-derived m/z 126 and 144 oxonium ions, differing in mass by H2 O, had completely different structures and that high-mannose N-glycopeptides generated abundant Hex-derived oxonium ions.	Mannose	140-147	hematopoietically expressed homeobox	Homo sapiens	18-21
26667170-0	2016	Mannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Induces CD4+ T Cell Anergy via GRAIL.	Mannose	0-7	ring finger protein 128	Homo sapiens	96-101
26667170-3	2016	We tested whether mannose-capped lipoarabinomannan (LAM)-induced inhibition of CD4(+) T cell activation resulted in CD4(+) T cell anergy.	Mannose	18-25	CD4 molecule	Homo sapiens	79-82
26667170-3	2016	We tested whether mannose-capped lipoarabinomannan (LAM)-induced inhibition of CD4(+) T cell activation resulted in CD4(+) T cell anergy.	Mannose	18-25	CD4 molecule	Homo sapiens	116-119
26611567-4	2016	DC-SIGN binds mannose or fucose-containing carbohydrates from viral proteins such as the HIV envelope glycoprotein gp120.	Mannose	14-21	CD209 molecule	Homo sapiens	0-7
26611567-4	2016	DC-SIGN binds mannose or fucose-containing carbohydrates from viral proteins such as the HIV envelope glycoprotein gp120.	Mannose	14-21	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	115-120
26763148-5	2016	Hereby, it is demonstrated for the first time that CEMP1 has a (C-type) lectin-like activity and specifically recognizes mannopyranoside.	Mannose	121-136	cementum protein 1	Homo sapiens	51-56
27373624-1	2016	In the endoplasmic reticulum (ER), uridine 5"-diphosphate-glucose: glycoprotein glucosyltransferase 1 (UGGT1) recognizes misfolded glycoproteins and transfers a glucose residue to the specific non-reducing end of high-mannose-type glycans.	Mannose	218-225	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	35-101
27373624-1	2016	In the endoplasmic reticulum (ER), uridine 5"-diphosphate-glucose: glycoprotein glucosyltransferase 1 (UGGT1) recognizes misfolded glycoproteins and transfers a glucose residue to the specific non-reducing end of high-mannose-type glycans.	Mannose	218-225	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	103-108
26430078-5	2016	We observed a &gt;80% decline in relative concentrations of the N-tetrasaccharide in MPI-CDG plasma after mannose therapy in 1 patient and in ALG1-CDG fibroblasts in vitro supplemented with mannose.	Mannose	190-197	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	142-146
27082983-6	2016	We show that whole parotid saliva and SAG, when coated to microplates, strongly interact with DC-SIGN and Langerin, probably via mannose and fucose structures.	Mannose	129-136	deleted in malignant brain tumors 1	Homo sapiens	38-41
26522247-3	2016	The results showed that Se-GP11 was composed of mannose, glucose and galactose with a molar ratio of 1:4.91:2.41.	Mannose	48-55	S100 calcium binding protein A10	Homo sapiens	27-31
27082983-4	2016	Both DC-SIGN and Langerin recognise mannose and fucose carbohydrate structures on pathogens and self-glycoproteins to regulate immunity and homeostasis.	Mannose	36-43	CD207 molecule	Homo sapiens	17-25
27082983-6	2016	We show that whole parotid saliva and SAG, when coated to microplates, strongly interact with DC-SIGN and Langerin, probably via mannose and fucose structures.	Mannose	129-136	CD207 molecule	Homo sapiens	106-114
27082983-8	2016	Furthermore, SAG binding to DC-SIGN or Langerin prevented binding to the micro-organisms Candida albicans and Escherichia coli which express mannose and fucose-containing glycan structures.	Mannose	141-148	deleted in malignant brain tumors 1	Homo sapiens	13-16
27082983-8	2016	Furthermore, SAG binding to DC-SIGN or Langerin prevented binding to the micro-organisms Candida albicans and Escherichia coli which express mannose and fucose-containing glycan structures.	Mannose	141-148	CD207 molecule	Homo sapiens	39-47
26440530-3	2016	MALDI-TOF MS analysis showed profound differences in glycosylation traits across the IgA isotypes and cell lines used for production, including sialylation and linkage thereof, fucosylation (both core and antennary) and the abundance of high-mannose type species.	Mannose	242-249	immunoglobulin heavy variable 4-38-2-like	Homo sapiens	85-88
26440530-5	2016	The polymerization propensity of anti-HER2 IgA2m2 could be suppressed by an 18-aa deletion of the heavy chain tailpiece - coinciding with the loss of high-mannose type N-glycan species - as well as by 2 cysteine to serine mutations at positions 320 and 480.	Mannose	155-162	erb-b2 receptor tyrosine kinase 2	Homo sapiens	38-42
26540494-1	2015	The glycoprotein gp120 of the HIV-1 viral envelope has a high content in mannose residues, particularly alpha-1,2-mannose oligomers.	Mannose	73-80	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	17-22
26670049-3	2015	In contrast, reduction of IgG glycosylation beyond the central mannose core is generally believed to result in impaired IgG activity.	Mannose	63-70	immunoglobulin heavy chain (V7183 family)	Mus musculus	26-29
26670049-3	2015	In contrast, reduction of IgG glycosylation beyond the central mannose core is generally believed to result in impaired IgG activity.	Mannose	63-70	immunoglobulin heavy chain (V7183 family)	Mus musculus	120-123
26682982-1	2015	The high-mannose patch on the HIV-1 envelope (Env) glycoprotein is the epicenter for binding of the potent broadly neutralizing PGT121 family of antibodies, but strategies for generating such antibodies by vaccination have not been defined.	Mannose	9-16	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	46-49
26540494-2	2015	Compounds that interact with these high-mannose type glycans may disturb the interaction between gp120 and its (co)receptors and are considered potential anti-HIV agents.	Mannose	40-47	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	97-102
26297290-0	2015	Mannose-binding Lectin (MBL) as a susceptible host factor influencing Indian Visceral Leishmaniasis.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
26260032-2	2015	Mannose-binding lectin/ficolin/collectin-associated protein (MAP-1) is a pattern recognition molecule (PRM)-associated inhibitor of the lectin pathway.	Mannose	0-7	MBL associated serine protease 1	Homo sapiens	61-66
26148749-4	2015	Among a set of 14 lectins, fibronectin mainly reacted with mannose-binding lectins, specifically concanavalin A.	Mannose	59-66	fibronectin 1	Homo sapiens	27-38
26297290-2	2015	Mannose-binding Lectin (MBL) is a complement lectin protein that binds to the surface of Leishmania promastigotes and results in activation of the complement lectin cascade.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
26256325-4	2015	PRM1 (143.2 kDa), PRM3 (105.3 kDa) and PRM5 (162.1 kDa) were heteropolysaccharides because they were composed of arabinose, mannose, glucose and galactose.	Mannose	124-131	protamine 1	Homo sapiens	0-4
26578673-2	2015	These bacteria adhere to mannose residues expressed by CEACAM6 on host cells in a type 1 pilus-dependent manner.	Mannose	25-32	CEA cell adhesion molecule 6	Homo sapiens	55-62
26578673-12	2015	Adherent-invasive Escherichia coli (AIEC) bacteria abnormally colonize the ileal mucosa of CD patients via the interaction of the mannose-specific adhesin FimH of type 1 pili with CEACAM6 mannosylated proteins expressed on the epithelial cell surface.	Mannose	130-137	CEA cell adhesion molecule 6	Homo sapiens	180-187
26277072-1	2015	The glycan shield on the human immunodeficiency virus 1 (HIV-1) envelope (Env) glycoprotein has drawn attention as a target for HIV-1 vaccine design given that an increasing number of potent and broadly neutralizing antibodies (bNAbs) recognize epitopes entirely or partially comprised of high mannose type N-linked glycans.	Mannose	294-301	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	74-77
26770645-0	2015	Erratum: Mannose-capped lipoarabinomannan from Mycobacterium tuberculosis induces IL-37 production via upregulating ERK1/2 and p38 in human type II alveolar epithelial cells.	Mannose	9-16	interleukin 37	Homo sapiens	82-87
26770645-0	2015	Erratum: Mannose-capped lipoarabinomannan from Mycobacterium tuberculosis induces IL-37 production via upregulating ERK1/2 and p38 in human type II alveolar epithelial cells.	Mannose	9-16	mitogen-activated protein kinase 3	Homo sapiens	116-122
26770645-0	2015	Erratum: Mannose-capped lipoarabinomannan from Mycobacterium tuberculosis induces IL-37 production via upregulating ERK1/2 and p38 in human type II alveolar epithelial cells.	Mannose	9-16	mitogen-activated protein kinase 1	Homo sapiens	127-130
26449894-7	2015	GC-MS results also demonstrated a significant overflow of several organic acids (pyruvate, 2-ketoglutarate and propanoate) and sugars (xylitol, mannose and fructose) in the mTNFalpha-producing strain.	Mannose	144-151	tumor necrosis factor	Mus musculus	173-182
26257149-6	2015	Approximately 45% of the bound PSA was eluted by using 0.1 M mannose as elution agent.	Mannose	61-68	kallikrein related peptidase 3	Homo sapiens	31-34
26355090-0	2015	Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.	Mannose	68-75	envelope protein	Simian immunodeficiency virus	54-57
26355090-1	2015	Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) envelope (Env) proteins are extensively decorated with N-glycans, predominantly of the high-mannose type.	Mannose	167-174	envelope protein	Simian immunodeficiency virus	85-88
26355090-2	2015	However, it is unclear how high-mannose N-glycans on Env impact viral spread.	Mannose	32-39	endogenous retrovirus group K member 20	Homo sapiens	53-56
26285173-8	2015	The effects of 2-DG on tube formation, MMP-2 activity, and VEGFR2 protein expression in HUVECs were reversed by mannose, an N-linked glycosylation precursor.	Mannose	112-119	matrix metallopeptidase 2	Rattus norvegicus	39-44
26285173-8	2015	The effects of 2-DG on tube formation, MMP-2 activity, and VEGFR2 protein expression in HUVECs were reversed by mannose, an N-linked glycosylation precursor.	Mannose	112-119	kinase insert domain receptor	Rattus norvegicus	59-65
26285173-9	2015	Mannose also reversed 2-DG-induced accumulation of VEGFR2 in the endoplasmic reticulum.	Mannose	0-7	kinase insert domain receptor	Rattus norvegicus	51-57
26133042-5	2015	H-Ficolin exhibited demonstrable binding to A. fumigatus conidia via l-fucose, d-mannose and N-acetylglucosamine residues in a calcium- and pH-dependent manner.	Mannose	79-88	ficolin 3	Homo sapiens	0-9
26130224-1	2015	The interaction between mannose-binding lectin [MBL]-associated serine protease-2 (MASP-2) and its first substrate, C4 is crucial to the lectin pathway of complement, which is vital for innate host immunity, but also involved in a number of inflammatory diseases.	Mannose	24-31	MBL associated serine protease 2	Homo sapiens	48-81
26130224-1	2015	The interaction between mannose-binding lectin [MBL]-associated serine protease-2 (MASP-2) and its first substrate, C4 is crucial to the lectin pathway of complement, which is vital for innate host immunity, but also involved in a number of inflammatory diseases.	Mannose	24-31	MBL associated serine protease 2	Homo sapiens	83-89
26817023-1	2015	OBJECTIVE: The lysosomal storage disease alpha-mannosidosis is caused by the deficiency of the lysosomal acid hydrolase alpha-mannosidase (LAMAN) leading to lysosomal accumulation of neutral mannose-linked oligosaccharides throughout the body, including the brain.	Mannose	191-198	mannosidase 2, alpha B1	Mus musculus	95-137
26817023-1	2015	OBJECTIVE: The lysosomal storage disease alpha-mannosidosis is caused by the deficiency of the lysosomal acid hydrolase alpha-mannosidase (LAMAN) leading to lysosomal accumulation of neutral mannose-linked oligosaccharides throughout the body, including the brain.	Mannose	191-198	mannosidase 2, alpha B1	Mus musculus	139-144
26296208-1	2015	In the yeast Saccharomyces cerevisiae, members of the Kre2/Mnt1 protein family have been shown to be alpha-1,2-mannosyltransferases or alpha-1,2-mannosylphosphate transferases, utilising an Mn2+-coordinated GDP-mannose as the sugar donor and a variety of mannose derivatives as acceptors.	Mannose	211-218	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	54-58
26270769-0	2015	Potential Use of Thioalkylated Mannose-Modified Dendrimer (G3)/alpha-Cyclodextrin Conjugate as an NF-kappaB siRNA Carrier for the Treatment of Fulminant Hepatitis.	Mannose	31-38	nuclear factor kappa B subunit 1	Homo sapiens	98-107
26062094-4	2015	We identified metal limitation and the alternate carbon source mannose as two environmental indicators likely to be encountered by GAS in the host that significantly induced the Rgg-SHP system.	Mannose	63-70	nuclear receptor subfamily 0 group B member 2	Homo sapiens	182-185
25969530-0	2015	Variants in the Mannose-binding Lectin Gene MBL2 do not Associate With Sepsis Susceptibility or Survival in a Large European Cohort.	Mannose	16-23	mannose binding lectin 2	Homo sapiens	44-48
26296208-1	2015	In the yeast Saccharomyces cerevisiae, members of the Kre2/Mnt1 protein family have been shown to be alpha-1,2-mannosyltransferases or alpha-1,2-mannosylphosphate transferases, utilising an Mn2+-coordinated GDP-mannose as the sugar donor and a variety of mannose derivatives as acceptors.	Mannose	211-218	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	59-63
26091901-3	2015	HPLC analysis showed that PAP consisted of D-mannose, D-ribose, l-rhamnose, D-glucuronic acid, D-glucose and D-galactose, and their corresponding mole percentages were 3.4%, 1.1%, 1.9%, 1.4%, 87.9% and 4.4%, respectively.	Mannose	43-52	regenerating family member 3 alpha	Homo sapiens	26-29
26111224-4	2015	Increasing mannose number (controlled through polymer chain length) and density (controlled through comonomer feed ratio of mannose versus galactose) result in greater interaction with MBL.	Mannose	11-18	mannose binding lectin 2	Homo sapiens	185-188
26111224-4	2015	Increasing mannose number (controlled through polymer chain length) and density (controlled through comonomer feed ratio of mannose versus galactose) result in greater interaction with MBL.	Mannose	124-131	mannose binding lectin 2	Homo sapiens	185-188
26101846-8	2015	Our results showed that alpha-L-fucosidase bound to fucose residue and in particular it prefers N-glycans carrying core alpha1,6-linked fucose and core alpha1,3-linked fucose in N-glycans carrying only a terminal mannose residue.	Mannose	213-220	alpha-L-fucosidase	Drosophila melanogaster	24-42
26089151-3	2015	Here, three hexose transporters (CsHT2, CsHT3, and CsHT4) were cloned from Cucumis sativus L. Heterologous expression in yeast demonstrated that CsHT3 transported glucose, galactose and mannose, with a K(m) of 131.9 muM for glucose, and CsHT4 only transported galactose, while CsHT2 was non-functional.	Mannose	186-193	sugar carrier protein C	Cucumis sativus	33-38
26089151-3	2015	Here, three hexose transporters (CsHT2, CsHT3, and CsHT4) were cloned from Cucumis sativus L. Heterologous expression in yeast demonstrated that CsHT3 transported glucose, galactose and mannose, with a K(m) of 131.9 muM for glucose, and CsHT4 only transported galactose, while CsHT2 was non-functional.	Mannose	186-193	sugar transport protein 14	Cucumis sativus	51-56
26089151-3	2015	Here, three hexose transporters (CsHT2, CsHT3, and CsHT4) were cloned from Cucumis sativus L. Heterologous expression in yeast demonstrated that CsHT3 transported glucose, galactose and mannose, with a K(m) of 131.9 muM for glucose, and CsHT4 only transported galactose, while CsHT2 was non-functional.	Mannose	186-193	hexose carrier protein HEX6	Cucumis sativus	145-150
26200113-5	2015	As starting materials, we used an anti-Her2 antibody produced in transgenic silkworm cocoon, which consists of non-fucosylated pauci-mannose type (Man2-3GlcNAc2), high-mannose type (Man4-9GlcNAc2), and complex type (Man3GlcNAc3-4) N-glycans.	Mannose	133-140	erb-b2 receptor tyrosine kinase 2	Homo sapiens	39-43
26050259-4	2015	A solid-phase binding study using sugar-biotinyl polymer probes revealed that fibrinogen has the highest affinity to mannose (Man) in both the presence and absence of 5 mM Ca(2+).	Mannose	117-124	fibrinogen beta chain	Homo sapiens	78-88
25940980-6	2015	Among potential lifespan-promoting substances, mannose-binding lectin and N-acetylcysteine were found to increase daf-16 expression.	Mannose	47-54	Fork-head domain-containing protein;Forkhead box protein O	Caenorhabditis elegans	114-120
25995448-3	2015	The C-type carbohydrate recognition domain in the extracellular portion of BDCA-2 contains a signature motif typical of C-type animal lectins that bind mannose, glucose, or GlcNAc, yet it has been reported that BDCA-2 binds selectively to galactose-terminated, biantennary N-linked glycans.	Mannose	152-159	C-type lectin domain family 4 member C	Homo sapiens	75-81
26062005-3	2015	To understand how the hydrolytic activity of GIIalpha is enhanced by the mannose 6-phosphate receptor (MPR) homology domain (MRH domain) of its beta subunit, we now report a 1.6 A resolution crystal structure of the MRH domain of GIIbeta bound to mannose.	Mannose	73-80	glucosidase II alpha subunit	Homo sapiens	45-53
26062005-3	2015	To understand how the hydrolytic activity of GIIalpha is enhanced by the mannose 6-phosphate receptor (MPR) homology domain (MRH domain) of its beta subunit, we now report a 1.6 A resolution crystal structure of the MRH domain of GIIbeta bound to mannose.	Mannose	73-80	progesterone receptor membrane component 1	Homo sapiens	103-106
25919894-1	2015	ZG16p is a soluble mammalian lectin that interacts with mannose and heparan sulfate.	Mannose	56-63	zymogen granule protein 16	Homo sapiens	0-5
25919894-4	2015	Saturation transfer difference (STD) NMR and transferred NOE experiments with chemically synthesized PIM glycans indicate that PIMs preferentially interact with ZG16p by using the mannose residues.	Mannose	180-187	zymogen granule protein 16	Homo sapiens	161-166
26261498-0	2015	Mannose prevents acute lung injury through mannose receptor pathway and contributes to regulate PPARgamma and TGF-beta1 level.	Mannose	0-7	peroxisome proliferator activated receptor gamma	Mus musculus	96-105
25878100-2	2015	One such antibody, PGT135, contacts the intrinsic mannose patch of gp120 at the Asn332, Asn392, and Asn386 glycosylation sites.	Mannose	50-57	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	67-72
25970848-1	2015	Monoglucosylated high-mannose-type glycan (Glc1Man9GlcNAc2: G1M9) is well-known as a key glycoform in the glycoprotein folding process, which is specifically recognized by lectin chaperones calnexin (CNX) and calreticulin (CRT) in the endoplasmic reticulum (ER).	Mannose	22-29	calnexin	Homo sapiens	190-198
25970848-1	2015	Monoglucosylated high-mannose-type glycan (Glc1Man9GlcNAc2: G1M9) is well-known as a key glycoform in the glycoprotein folding process, which is specifically recognized by lectin chaperones calnexin (CNX) and calreticulin (CRT) in the endoplasmic reticulum (ER).	Mannose	22-29	calnexin	Homo sapiens	200-203
25970848-1	2015	Monoglucosylated high-mannose-type glycan (Glc1Man9GlcNAc2: G1M9) is well-known as a key glycoform in the glycoprotein folding process, which is specifically recognized by lectin chaperones calnexin (CNX) and calreticulin (CRT) in the endoplasmic reticulum (ER).	Mannose	22-29	calreticulin	Homo sapiens	209-221
26261498-8	2015	Interestingly, competitive inhibition of MR with mannan was associated with elimination of the anti-inflammatory effects of mannose, and reversed effects of mannose of regulation to PPARgamma and TGF-beta1.	Mannose	157-164	peroxisome proliferator activated receptor gamma	Mus musculus	182-191
26261498-0	2015	Mannose prevents acute lung injury through mannose receptor pathway and contributes to regulate PPARgamma and TGF-beta1 level.	Mannose	0-7	transforming growth factor, beta 1	Mus musculus	110-119
26261498-8	2015	Interestingly, competitive inhibition of MR with mannan was associated with elimination of the anti-inflammatory effects of mannose, and reversed effects of mannose of regulation to PPARgamma and TGF-beta1.	Mannose	157-164	transforming growth factor, beta 1	Mus musculus	196-205
26261498-7	2015	Mannose increased PPARgamma and MR expression, and inhibited TGF-beta1 stimulated by LPS.	Mannose	0-7	peroxisome proliferator activated receptor gamma	Mus musculus	18-27
26261498-7	2015	Mannose increased PPARgamma and MR expression, and inhibited TGF-beta1 stimulated by LPS.	Mannose	0-7	transforming growth factor, beta 1	Mus musculus	61-70
26221267-0	2015	Mannose-capped Lipoarabinomannan from Mycobacterium tuberculosis induces IL-37 production via upregulating ERK1/2 and p38 in human type II alveolar epithelial cells.	Mannose	0-7	interleukin 37	Homo sapiens	73-78
26221267-0	2015	Mannose-capped Lipoarabinomannan from Mycobacterium tuberculosis induces IL-37 production via upregulating ERK1/2 and p38 in human type II alveolar epithelial cells.	Mannose	0-7	mitogen-activated protein kinase 3	Homo sapiens	107-113
26221267-0	2015	Mannose-capped Lipoarabinomannan from Mycobacterium tuberculosis induces IL-37 production via upregulating ERK1/2 and p38 in human type II alveolar epithelial cells.	Mannose	0-7	mitogen-activated protein kinase 1	Homo sapiens	118-121
25481681-1	2015	UGGT1 is called as a folding sensor protein that recognizes misfolded glycoproteins and selectively glucosylates high-mannose-type glycans on the proteins.	Mannose	118-125	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	0-5
25691525-7	2015	The presence of glucose/mannose causes the dephosphorylation of P~EIIB(Mpo) and P~PRD2 of ManR, which together lead to the induction of the manLMN operon.	Mannose	24-31	myeloperoxidase	Homo sapiens	71-74
25771043-5	2015	The milk samples from cows with the DGAT1 KK genotype contained more stomatin, sphingomyelin, choline, and carnitine, and less citrate, creatine or phosphocreatine, glycerol-phosphocholine, mannose-like sugar, acetyl sugar phosphate, uridine diphosphate (UDP)-related sugar, and orotic acid compared with milk samples from cows with the DGAT1 AA genotype.	Mannose	190-197	diacylglycerol O-acyltransferase 1	Bos taurus	36-41
25678342-3	2015	Hxt1 was characterized as a high-affinity transporter for glucose, fructose, and mannose;  hxt1 strains show significantly reduced growth on these substrates, setting Hxt1 as the main hexose transporter during saprophytic growth.	Mannose	81-88	hexose transporter HXT1	Saccharomyces cerevisiae S288C	0-4
25481681-3	2015	We have demonstrated that high-mannose-type glycans, in which various hydrophobic aglycons were introduced, act as good substrates for UGGT1 and are useful analytical tools for its characterization.	Mannose	31-38	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	135-140
25912189-11	2015	CONCLUSIONS: We have established the sugar specificity of CL-K1 and demonstrated that it targets high-mannose oligosaccharides on self- and non-self structures via an extended binding site which recognises the terminal two mannose residues of the carbohydrate ligand.	Mannose	102-109	collectin subfamily member 11	Homo sapiens	58-63
25737452-3	2015	Our previous work demonstrated that receptor protein-tyrosine phosphatase zeta (RPTPzeta)/phosphacan is hypoglycosylated in a mouse model of one of these CMDs, known as muscle-eye-brain disease, a disorder that is caused by loss of an enzyme (protein O-mannose beta-1,2-N-acetylglucosaminyltransferase 1) that modifies O-mannosyl glycans.	Mannose	253-260	protein tyrosine phosphatase, receptor type Z, polypeptide 1	Mus musculus	36-78
25737452-3	2015	Our previous work demonstrated that receptor protein-tyrosine phosphatase zeta (RPTPzeta)/phosphacan is hypoglycosylated in a mouse model of one of these CMDs, known as muscle-eye-brain disease, a disorder that is caused by loss of an enzyme (protein O-mannose beta-1,2-N-acetylglucosaminyltransferase 1) that modifies O-mannosyl glycans.	Mannose	253-260	protein tyrosine phosphatase, receptor type Z, polypeptide 1	Mus musculus	80-88
25781619-9	2015	Mannose but not pyruvate rescued GIST cells from 2DG-induced growth arrest, suggesting that loss of KIT integrity is the predominant effect of 2DG in GIST.	Mannose	0-7	KIT proto-oncogene, receptor tyrosine kinase	Homo sapiens	100-103
25658064-1	2015	Three new triazole conjugates derived from d-mannose were synthesized and assayed in in vitro assays to investigate their ability to inhibit alpha-mannosidase enzymes from the glycoside hydrolase (GH) families 38 and 47.	Mannose	43-52	alpha-Mannosidase class II b	Drosophila melanogaster	141-158
26281585-2	2015	The results showed that P1 A had a backbone consisting rhamnose, mannose, glucose and galactose.	Mannose	65-72	zinc finger protein 185 with LIM domain	Homo sapiens	24-28
25736428-2	2015	The VS SAMs were used as a model system to assess the reaction kinetics of bioactive ligands, i.e., glutathione (GSH), N-(5-amino-1-carboxypentyl)iminodiacetic acid (ab-NTA), and mannose, toward the VS groups on the SAM surface.	Mannose	179-186	methionine adenosyltransferase 1A	Homo sapiens	7-11
25793526-8	2015	Preliminary biochemical characterization demonstrates that the component seems to be large (&gt;100kDa), heat and proteinase K resistant, binds in a alpha1-3 mannose independent manner and is highly variant between individuals.	Mannose	158-165	adrenoceptor alpha 1D	Homo sapiens	149-157
25548381-3	2015	The recognition molecules of the lectin pathway of complement activation, mannose-binding lectin (MBL), ficolins, and CL-11, bind to specific carbohydrates on pathogens, triggering complement activation through MBL-associated serine protease-2 (MASP-2).	Mannose	74-81	mannose-binding lectin (protein C) 2	Mus musculus	98-101
25498624-5	2015	GIP-II was composed of galactose, glucose, xylose, and mannose, with glucose was the predominant monosaccharide.	Mannose	55-62	gastric inhibitory polypeptide	Homo sapiens	0-3
25634695-1	2015	Mannose-binding lectin (MBL), a pattern-recognition molecule in serum, recognizes specific hexose sugars rich in mannose and N-acetylglucosamine on bacterium, yeasts, viruses as well as apoptotic cells.	Mannose	113-120	mannose binding lectin 2	Homo sapiens	0-22
25634695-1	2015	Mannose-binding lectin (MBL), a pattern-recognition molecule in serum, recognizes specific hexose sugars rich in mannose and N-acetylglucosamine on bacterium, yeasts, viruses as well as apoptotic cells.	Mannose	113-120	mannose binding lectin 2	Homo sapiens	24-27
24608429-7	2015	The binding of SP-D to sEGFR was suppressed by EDTA, mannose or N-glycopeptidase F treatment.	Mannose	53-60	surfactant protein D	Homo sapiens	15-19
24608429-8	2015	Mass spectrometric analysis indicated that N-glycans in domain III of EGFR were of a high-mannose type.	Mannose	90-97	epidermal growth factor receptor	Homo sapiens	70-74
25586968-1	2015	A comprehensive method for the construction of a high-mannose-type glycan library by systematic chemo-enzymatic trimming of a single Man9-based precursor was developed.	Mannose	54-61	mannosidase alpha class 1A member 1	Homo sapiens	133-137
24608429-5	2015	A ligand blot indicated that SP-D bound to EGFR, and a lectin blot suggested that EGFR in A549 cells had both high-mannose type and complex type N-glycans.	Mannose	115-122	epidermal growth factor receptor	Homo sapiens	82-86
25515338-4	2015	Using AFM tips labelled with mannose, we detect single flocculins on Flo1-expressing cells, showing they are widely exposed on the cell surface.	Mannose	29-36	flocculin FLO1	Saccharomyces cerevisiae S288C	69-73
25548381-3	2015	The recognition molecules of the lectin pathway of complement activation, mannose-binding lectin (MBL), ficolins, and CL-11, bind to specific carbohydrates on pathogens, triggering complement activation through MBL-associated serine protease-2 (MASP-2).	Mannose	74-81	mannose-binding lectin (protein C) 2	Mus musculus	211-214
25548381-3	2015	The recognition molecules of the lectin pathway of complement activation, mannose-binding lectin (MBL), ficolins, and CL-11, bind to specific carbohydrates on pathogens, triggering complement activation through MBL-associated serine protease-2 (MASP-2).	Mannose	74-81	mannan-binding lectin serine peptidase 2	Mus musculus	245-251
25226443-2	2015	In the present study, we demonstrated that phagocytosis mediated by a mouse mannose-binding CLR, SIGNR1 significantly suppressed the LPS-induced secretion of the specific pro-inflammatory cytokines from the resident peritoneal macrophages and the mouse macrophage-like cells that express SIGNR1 (RAW-SIGNR1).	Mannose	76-83	CD209b antigen	Mus musculus	97-103
25468650-7	2015	In plasma, GLA was present as the 46kDa mature form, which lacks the mannose 6-phosphorylated moiety and is not able to be efficiently endocytosed by affected cells.	Mannose	69-76	galactosidase alpha	Homo sapiens	11-14
25483429-1	2015	We hypothesized that the co-entrapment of melanoma-associated antigens and the Toll-like receptor (TLR) ligands Poly(I:C) and CpG, known to be Th1-immunopotentiators, in mannose-functionalized aliphatic polyester-based nanoparticles (NPs) could be targeted to mannose receptors on antigen-presenting cells and induce anti-tumor immune responses.	Mannose	170-177	negative elongation factor complex member C/D, Th1l	Mus musculus	143-146
25483429-4	2015	Mannose-functionalization of NPs potentiated the Th1 immune response.	Mannose	0-7	negative elongation factor complex member C/D, Th1l	Mus musculus	49-52
25155442-12	2015	PRX-102 has a relatively simple glycosylation pattern, characteristic to plants, having mainly tri-mannose structures with the addition of either alpha(1-3)-linked fucose or beta(1-2)-linked xylose, or both, in addition to various high mannose structures, while agalsidase beta has a mixture of sialylated glycans in addition to high mannose structures.	Mannose	99-106	periaxin	Homo sapiens	0-3
25155442-12	2015	PRX-102 has a relatively simple glycosylation pattern, characteristic to plants, having mainly tri-mannose structures with the addition of either alpha(1-3)-linked fucose or beta(1-2)-linked xylose, or both, in addition to various high mannose structures, while agalsidase beta has a mixture of sialylated glycans in addition to high mannose structures.	Mannose	236-243	periaxin	Homo sapiens	0-3
25535195-7	2015	The transgenic lines expressing the SND2 or ANAC075 chimeric activator showed increased glucose and xylose, and lower lignin content, whereas the transgenic line expressing the MYB46 chimeric activator showed increased mannose content.	Mannose	219-226	myb domain protein 46	Arabidopsis thaliana	177-182
25525995-2	2015	Structure characterization revealed that DP1 had an average molecular weight of 1132 kDa and consisted of glucose (56.2%), galactose (14.1%), and mannose (29.7%).	Mannose	146-153	transcription factor Dp 1	Mus musculus	41-44
25477510-6	2015	C. neoformans KTR3, the only homolog of the Saccharomyces cerevisiae KRE2/MNT1 family genes, was shown to encode an alpha1,2-mannosyltransferase responsible for the addition of the second mannose residue via an alpha1,2-linkage to the major O-glycans.	Mannose	188-195	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	69-73
25477510-6	2015	C. neoformans KTR3, the only homolog of the Saccharomyces cerevisiae KRE2/MNT1 family genes, was shown to encode an alpha1,2-mannosyltransferase responsible for the addition of the second mannose residue via an alpha1,2-linkage to the major O-glycans.	Mannose	188-195	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	74-78
26339568-7	2015	This is the first study indicating that beta1 and beta3 integrins bearing high-mannose/hybrid structures are affected by Rapa and CsA.	Mannose	79-86	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	40-55
25226443-2	2015	In the present study, we demonstrated that phagocytosis mediated by a mouse mannose-binding CLR, SIGNR1 significantly suppressed the LPS-induced secretion of the specific pro-inflammatory cytokines from the resident peritoneal macrophages and the mouse macrophage-like cells that express SIGNR1 (RAW-SIGNR1).	Mannose	76-83	CD209b antigen	Mus musculus	288-294
25226443-2	2015	In the present study, we demonstrated that phagocytosis mediated by a mouse mannose-binding CLR, SIGNR1 significantly suppressed the LPS-induced secretion of the specific pro-inflammatory cytokines from the resident peritoneal macrophages and the mouse macrophage-like cells that express SIGNR1 (RAW-SIGNR1).	Mannose	76-83	CD209b antigen	Mus musculus	296-306
25329733-7	2015	Cd stress-induced expression of MAN3 and the consequently increased mannanase activity, led to increased mannose content in cell walls.	Mannose	105-112	Glycosyl hydrolase superfamily protein	Arabidopsis thaliana	32-36
25213400-11	2015	The most mannose rich are the glycans MS2 and GP4, each of them has four mannoses; OPPE1 contains five N-acetylglucosamines and one sulfated glucuronic acid; GP4 contains one sialic acid.	Mannose	9-16	MS2	Homo sapiens	38-41
25213400-11	2015	The most mannose rich are the glycans MS2 and GP4, each of them has four mannoses; OPPE1 contains five N-acetylglucosamines and one sulfated glucuronic acid; GP4 contains one sialic acid.	Mannose	9-16	CD36 molecule	Homo sapiens	46-49
25213400-11	2015	The most mannose rich are the glycans MS2 and GP4, each of them has four mannoses; OPPE1 contains five N-acetylglucosamines and one sulfated glucuronic acid; GP4 contains one sialic acid.	Mannose	9-16	CD36 molecule	Homo sapiens	158-161
25213400-11	2015	The most mannose rich are the glycans MS2 and GP4, each of them has four mannoses; OPPE1 contains five N-acetylglucosamines and one sulfated glucuronic acid; GP4 contains one sialic acid.	Mannose	73-81	MS2	Homo sapiens	38-41
25213400-11	2015	The most mannose rich are the glycans MS2 and GP4, each of them has four mannoses; OPPE1 contains five N-acetylglucosamines and one sulfated glucuronic acid; GP4 contains one sialic acid.	Mannose	73-81	CD36 molecule	Homo sapiens	46-49
25329733-8	2015	Moreover, mannose treatment not only rescued the Cd-sensitive phenotype of the xcd1-2 mutant, but also improved the Cd tolerance of wild-type plants.	Mannose	10-17	Glycosyl hydrolase superfamily protein	Arabidopsis thaliana	79-83
25956563-1	2015	OBJECTIVE: To investigate effect of mannose-binding lectin (MBL) genetic polymorphisms and phenotype in chronic hepatitis C and its impact on response to antiviral therapy in children.	Mannose	36-43	mannose binding lectin 2	Homo sapiens	60-63
26458310-6	2015	Also, 39 common genes, like PFKP (phosphofructokinase, platelet) and DGKH-rs11616202 (diacylglycerol kinase, eta) that enriched in sub-pathways such as galactose metabolism, fructose and mannose metabolism, and pentose phosphate pathway, were identified as the lung cancer oncogenes.	Mannose	187-194	phosphofructokinase, platelet	Homo sapiens	28-32
26458310-6	2015	Also, 39 common genes, like PFKP (phosphofructokinase, platelet) and DGKH-rs11616202 (diacylglycerol kinase, eta) that enriched in sub-pathways such as galactose metabolism, fructose and mannose metabolism, and pentose phosphate pathway, were identified as the lung cancer oncogenes.	Mannose	187-194	diacylglycerol kinase eta	Homo sapiens	69-73
26458310-6	2015	Also, 39 common genes, like PFKP (phosphofructokinase, platelet) and DGKH-rs11616202 (diacylglycerol kinase, eta) that enriched in sub-pathways such as galactose metabolism, fructose and mannose metabolism, and pentose phosphate pathway, were identified as the lung cancer oncogenes.	Mannose	187-194	endothelin receptor type A	Homo sapiens	109-112
26458310-8	2015	Our study suggested that PFKP and DGKH that enriched in galactose metabolism, fructose and mannose metabolism pathway, as well as PIK3R1, RORA, and MAGI3, may be the lung cancer oncogenes.	Mannose	91-98	phosphofructokinase, platelet	Homo sapiens	25-29
26458310-8	2015	Our study suggested that PFKP and DGKH that enriched in galactose metabolism, fructose and mannose metabolism pathway, as well as PIK3R1, RORA, and MAGI3, may be the lung cancer oncogenes.	Mannose	91-98	diacylglycerol kinase eta	Homo sapiens	34-38
25324542-2	2014	Phosphomannomutase2, a homodimer in which each chain is composed of two domains, requires a bisphosphate sugar (either mannose or glucose) as activator, opening a possible drug design path for therapeutic purposes.	Mannose	119-126	phosphomannomutase 2	Homo sapiens	0-19
25403811-1	2014	The anti-HIV lectin actinohivin (AH) specifically interacts with HMTG (high-mannose-type glycan), which is attached to the glycoprotein gp120 of HIV-1 in a process in which the three branched mannotriose chains (D1, D2, and D3) of HMTG exhibit different binding affinities, it being estimated that that of D1 is the strongest, that of D3 is weaker, and that of D2 is undetectable.	Mannose	76-83	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	136-141
25455227-2	2014	Our results showed that the obtained MLP (purity 99.8%) was determined to be composed of d-arabinose, d-xylose, d-glucose, d-rhamnose and d-mannose with molar ratio of 1:2.13:6.53:1.04:8.73.	Mannose	138-147	cysteine and glycine rich protein 3	Rattus norvegicus	37-40
25500577-4	2014	These two enzymes catalyzed the synthesis of 1,2-beta-oligomannan using beta-1,2-mannobiose and d-mannose as the optimal acceptors, respectively, in the presence of the donor alpha-d-mannose 1-phosphate.	Mannose	96-105	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	72-80
24977653-1	2014	Mannose binding lectin (MBL2) is a soluble pattern recognition receptor that is key to generating innate immune responses to invasive infection, including against the cardinal Gram-negative bacterium Neisseria meningitidis.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-28
25479762-11	2014	We also validate the implementation of the Microcystis aeruginosa lectin, microvirin, in this platform and provide refined evidence for its efficacy in specifically recognizing high-mannose-type N-glycans, a class of carbohydrate modification that is distinctive of hGGT1 expressed by many tumors.	Mannose	182-189	gamma-glutamyltransferase 1	Homo sapiens	266-271
25305020-3	2014	In the present study, we purified the glycosylated extracellular domain of calcium-sensing receptor (CaSR) (ECD) (residues 20-612), containing either complex or high mannose N-glycan structures depending on the host cell line employed for recombinant expression.	Mannose	166-173	calcium sensing receptor	Homo sapiens	75-99
25305020-3	2014	In the present study, we purified the glycosylated extracellular domain of calcium-sensing receptor (CaSR) (ECD) (residues 20-612), containing either complex or high mannose N-glycan structures depending on the host cell line employed for recombinant expression.	Mannose	166-173	calcium sensing receptor	Homo sapiens	101-105
25130689-5	2014	The resulting mannose-linked PGMMAs confirm a safe cytotoxic profile and are able to stimulate cytokine production (TNFalpha), membrane protein expression (CD40), and cellular uptake in bone marrow derived dendritic cells.	Mannose	14-21	CD40 molecule	Homo sapiens	156-160
25004930-6	2014	Data analysis revealed marked differences between Fab and Fc glycosylation, especially in the levels of galactosylation and sialylation, incidence of bisecting GlcNAc, and presence of high mannose structures, which were all higher in the Fab portion than the Fc, whereas Fc showed higher levels of fucosylation.	Mannose	189-196	FA complementation group B	Homo sapiens	50-53
25165136-0	2014	Cdc1 removes the ethanolamine phosphate of the first mannose of GPI anchors and thereby facilitates the integration of GPI proteins into the yeast cell wall.	Mannose	53-60	putative lipid phosphatase CDC1	Saccharomyces cerevisiae S288C	0-4
25165136-2	2014	A recent report showed that PGAP5, a human homologue of CDC1, acts as a phosphodiesterase removing an ethanolamine phosphate (EtN-P) from mannose 2 of the glycosylphosphatidylinositol (GPI) anchor, thus permitting efficient endoplasmic reticulum (ER)-to-Golgi transport of GPI proteins.	Mannose	138-145	metallophosphoesterase 1	Homo sapiens	28-33
25165136-2	2014	A recent report showed that PGAP5, a human homologue of CDC1, acts as a phosphodiesterase removing an ethanolamine phosphate (EtN-P) from mannose 2 of the glycosylphosphatidylinositol (GPI) anchor, thus permitting efficient endoplasmic reticulum (ER)-to-Golgi transport of GPI proteins.	Mannose	138-145	putative lipid phosphatase CDC1	Saccharomyces cerevisiae S288C	56-60
25004930-6	2014	Data analysis revealed marked differences between Fab and Fc glycosylation, especially in the levels of galactosylation and sialylation, incidence of bisecting GlcNAc, and presence of high mannose structures, which were all higher in the Fab portion than the Fc, whereas Fc showed higher levels of fucosylation.	Mannose	189-196	FA complementation group B	Homo sapiens	238-241
25142936-4	2014	In brain s-eNPP6 the N-glycans are mainly hybrid and high mannose type structures, reminiscent of processed mannose-6-phosphorylated glycans.	Mannose	58-65	ectonucleotide pyrophosphatase/phosphodiesterase 6	Bos taurus	11-16
25193139-5	2014	Although yeast OS-9 is composed of a well-established N-terminal mannose recognition homology lectin domain and a C-terminal dimerization domain, we find that the C-terminal domain of OS-9 in higher eukaryotes contains "mammalian-specific insets" that are specifically recognized by the middle and C-terminal domains of Grp94.	Mannose	65-72	OS9 endoplasmic reticulum lectin	Homo sapiens	15-19
25193139-5	2014	Although yeast OS-9 is composed of a well-established N-terminal mannose recognition homology lectin domain and a C-terminal dimerization domain, we find that the C-terminal domain of OS-9 in higher eukaryotes contains "mammalian-specific insets" that are specifically recognized by the middle and C-terminal domains of Grp94.	Mannose	65-72	OS9 endoplasmic reticulum lectin	Homo sapiens	184-188
26146546-8	2014	DC interactions with mannose conjugates were found to be calcium dependent and could be inhibited via anti-DC-SIGN antibodies.	Mannose	21-28	CD209 molecule	Homo sapiens	107-114
25313559-0	2014	Extreme high prevalence of a defective mannose-binding lectin (MBL2) genotype in native South American West Andean populations.	Mannose	39-46	mannose binding lectin 2	Homo sapiens	63-67
25313559-1	2014	Mannose-binding lectin (MBL) is one of the five recognition molecules in the lectin complement pathway.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
25213646-2	2014	A previous study demonstrated that mannose glycation (mannosylation) of ovalbumin decreased allergenicity in vivo.	Mannose	35-42	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	72-81
25034232-5	2014	C1 esterase inhibitor (C1INH) is an endogenous human plasma protein that has broad inhibitory activity in the complement pathway through inhibition of the classical pathway by binding C1r and C1s and inhibits the mannose-binding lectin-associated serine proteases in the lectin pathway.	Mannose	213-220	serpin family G member 1	Homo sapiens	0-21
25034232-5	2014	C1 esterase inhibitor (C1INH) is an endogenous human plasma protein that has broad inhibitory activity in the complement pathway through inhibition of the classical pathway by binding C1r and C1s and inhibits the mannose-binding lectin-associated serine proteases in the lectin pathway.	Mannose	213-220	serpin family G member 1	Homo sapiens	23-28
25121780-2	2014	DC-SIGN mediates interactions among dendritic cells, pathogens, and a variety of epithelia, myeloid cells, and endothelia by binding to high mannose residues on pathogenic invaders or fucosylated residues on the membranes of other immune cells.	Mannose	141-148	CD209 molecule	Homo sapiens	0-7
25131860-8	2014	LC-ESI-MS glycosylation analysis showed that the high-mannose glycosylated form of HE4 expressed by P. pastoris has lower biological activity when compared to its complex-glycosylated form produced from HEK293-F cells.	Mannose	54-61	WAP four-disulfide core domain 2	Homo sapiens	83-86
25132301-6	2014	METHODS: N-Glycans were released from ribonuclease B, ovalbumin and gp120 with endoH to give high-mannose and hybrid glycans, and from IgG with endoS to produce biantennary complex glycans, all missing the reducing-terminal GlcNAc residue.	Mannose	98-105	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	68-73
25176311-0	2014	Dectin-2 is a direct receptor for mannose-capped lipoarabinomannan of mycobacteria.	Mannose	34-41	C-type lectin domain containing 6A	Homo sapiens	0-8
25237315-6	2014	It has been hypothesized that cytosolic PNGase (cPNGase) and ENGase in animal cells are involved in the production of high-mannose type FNGs in order to release N-glycans from the misfolded glycoproteins in the protein quality control systems.	Mannose	123-130	N-glycanase 1	Homo sapiens	40-46
25237315-6	2014	It has been hypothesized that cytosolic PNGase (cPNGase) and ENGase in animal cells are involved in the production of high-mannose type FNGs in order to release N-glycans from the misfolded glycoproteins in the protein quality control systems.	Mannose	123-130	endo-beta-N-acetylglucosaminidase	Homo sapiens	61-67
24965454-2	2014	2G12 is a unique, domain-exchanged antibody that binds exclusively to conserved N-linked glycans that form the high-mannose patch on the gp120 outer domain centered on a glycan at position N332.	Mannose	116-123	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	137-142
24842046-5	2014	This interaction, which was blocked by D-mannose, induced cell activation, as manifested by increased mitochondrial activity, interleukin-2 production, and cell proliferation.	Mannose	39-48	interleukin 2	Mus musculus	126-139
24825317-3	2014	Our results show that mannose binding lectin (MBL) that binds to the N-linked mannose residues on gp120, participates in intravesicular packaging of gp120 in neuronal subcellular organelles and also in subcellular trafficking of these vesicles in neuronal cells.	Mannose	22-29	mannose binding lectin 2	Homo sapiens	46-49
24825317-3	2014	Our results show that mannose binding lectin (MBL) that binds to the N-linked mannose residues on gp120, participates in intravesicular packaging of gp120 in neuronal subcellular organelles and also in subcellular trafficking of these vesicles in neuronal cells.	Mannose	22-29	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	98-103
24825317-3	2014	Our results show that mannose binding lectin (MBL) that binds to the N-linked mannose residues on gp120, participates in intravesicular packaging of gp120 in neuronal subcellular organelles and also in subcellular trafficking of these vesicles in neuronal cells.	Mannose	22-29	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	149-154
25060516-2	2014	OBJECTIVE: The aim of this study was to determine whether functional mannose-binding lectin gene (MBL) polymorphisms are associated with the susceptibility to rheumatoid arthritis (RA) or primary Sjogren"s syndrome (pSS).	Mannose	69-76	mannose binding lectin 2	Homo sapiens	98-101
24850474-0	2014	Antitumor effect of nuclear factor-kappaB decoy transfer by mannose-modified bubble lipoplex into macrophages in mouse malignant ascites.	Mannose	60-67	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	20-41
25092655-6	2014	Based on the presence of two rate-limiting steps in mammalian gpERAD, we propose that mammalian cells double check gpERAD substrates before destruction by evolving EDEM2, a novel-type Htm1 homologue that catalyzes the first mannose trimming step from Man9GlcNAc2.	Mannose	224-231	alpha-1,2-mannosidase MNL1	Saccharomyces cerevisiae S288C	184-188
24771334-3	2014	We investigated the effect of genetic variation in the mannose-binding lectin gene, MBL2, on susceptibility and disease severity of IPD in previously healthy children aged &lt;5 years.	Mannose	55-62	mannose binding lectin 2	Homo sapiens	84-88
25092655-0	2014	EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step.	Mannose	68-75	ER degradation enhancing alpha-mannosidase like protein 2	Homo sapiens	0-5
25092655-1	2014	Glycoproteins misfolded in the endoplasmic reticulum (ER) are subjected to ER-associated glycoprotein degradation (gpERAD) in which Htm1-mediated mannose trimming from the oligosaccharide Man8GlcNAc2 to Man7GlcNAc2 is the rate-limiting step in yeast.	Mannose	146-153	alpha-1,2-mannosidase MNL1	Saccharomyces cerevisiae S288C	132-136
25092655-4	2014	Mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 is performed mainly by EDEM3 and to a lesser extent by EDEM1.	Mannose	0-7	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	72-77
25092655-4	2014	Mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 is performed mainly by EDEM3 and to a lesser extent by EDEM1.	Mannose	0-7	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	104-109
25092655-5	2014	Most surprisingly, the upstream mannose trimming from Man9GlcNAc2 to Man8GlcNAc2 is conducted mainly by EDEM2, which was previously considered to lack enzymatic activity.	Mannose	32-39	ER degradation enhancing alpha-mannosidase like protein 2	Homo sapiens	104-109
25092655-6	2014	Based on the presence of two rate-limiting steps in mammalian gpERAD, we propose that mammalian cells double check gpERAD substrates before destruction by evolving EDEM2, a novel-type Htm1 homologue that catalyzes the first mannose trimming step from Man9GlcNAc2.	Mannose	224-231	ER degradation enhancing alpha-mannosidase like protein 2	Homo sapiens	164-169
24850474-5	2014	Here, we developed targeted transfer of a NF-kappaB decoy into TAMs by ultrasound (US)-responsive, mannose-modified liposome/NF-kappaB decoy complexes (Man-PEG bubble lipoplexes) in a mouse peritoneal dissemination model of Ehrlich ascites carcinoma.	Mannose	99-106	nuclear factor kappa B subunit 1	Homo sapiens	42-51
24850474-5	2014	Here, we developed targeted transfer of a NF-kappaB decoy into TAMs by ultrasound (US)-responsive, mannose-modified liposome/NF-kappaB decoy complexes (Man-PEG bubble lipoplexes) in a mouse peritoneal dissemination model of Ehrlich ascites carcinoma.	Mannose	99-106	nuclear factor kappa B subunit 1	Homo sapiens	125-134
24976257-8	2014	Our results lead us to propose that the DC-SIGNR CRD rapidly and reversibly releases glycan ligands and Ca(2+) at reduced pH (behaviour that would be expected for an endocytic receptor), and that the binding of mannose-containing oligosaccharides is more strongly affected by pH than the binding of GlcNAc-containing oligosaccharides.	Mannose	211-218	C-type lectin domain family 4 member M	Homo sapiens	40-48
24884609-9	2014	Site N274 contained high-mannose N-linked glycans in both serum and recombinant ITIH4.	Mannose	25-32	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	80-85
24372710-6	2014	For the three recombinant FVIII products, we compared the binding to the mannose-sensitive endocytic receptor CD206, the dose-dependent endocytosis by immature monocyte-derived dendritic cells (DCs), the activation by FVIII-loaded DCs of a FVIII-specific HLA-DRB1*0101-restricted mouse T-cell hybridoma and the induction of inhibitory anti-FVIII IgG in FVIII-deficient mice.	Mannose	73-80	coagulation factor VIII	Mus musculus	26-31
24746228-10	2014	Surfaces displaying terminal alpha1-2 linked mannose structures were able to increase the inflammatory DC response to a greater extent than did any other terminal glycan structure.	Mannose	45-52	adrenoceptor alpha 1D	Homo sapiens	29-37
24372710-6	2014	For the three recombinant FVIII products, we compared the binding to the mannose-sensitive endocytic receptor CD206, the dose-dependent endocytosis by immature monocyte-derived dendritic cells (DCs), the activation by FVIII-loaded DCs of a FVIII-specific HLA-DRB1*0101-restricted mouse T-cell hybridoma and the induction of inhibitory anti-FVIII IgG in FVIII-deficient mice.	Mannose	73-80	mannose receptor, C type 1	Mus musculus	110-115
25028560-6	2014	The mannose moieties of (99m)Tc-tilmanosept facilitate its binding to mannose receptors (CD206) expressed in reticuloendothelial cells of the SLN.	Mannose	4-11	mannose receptor C-type 1	Homo sapiens	89-94
24790092-2	2014	ZG16p has been reported to bind both to glycosaminoglycans and mannose.	Mannose	63-70	zymogen granule protein 16	Homo sapiens	0-5
24950659-3	2014	The collectins surfactant protein (SP)-A1, -A2, and -D and mannose-binding lectin (MBL) neutralize IAV infectivity, although only SP-A2 can establish an efficient neutralization of poorly glycosylated pandemic IAV strains.	Mannose	59-66	mannose binding lectin 2	Homo sapiens	83-86
24790092-4	2014	We observed that ZG16p preferentially binds to alpha-mannose-terminating short glycans such as Ser/Thr-linked O-mannose, but not to high mannose-type N-glycans.	Mannose	53-60	zymogen granule protein 16	Homo sapiens	17-22
24724545-6	2014	In TGFbeta-induced EMT, levels of high-mannose-type N-glycans were enhanced, antennary N-glycans, and fucosylation were suppressed, and bisecting GlcNAc N-glycans were greatly suppressed.	Mannose	39-46	transforming growth factor, beta 1	Mus musculus	3-10
24901869-2	2014	We further showed that levels of mannose binding lectin (MBL; required for effective macrophage phagocytic function) were reduced in the airways but not circulation of COPD patients.	Mannose	33-40	mannose binding lectin 2	Homo sapiens	57-60
24631548-2	2014	The r-EPS1 and r-EPS2 were homogenous polysaccharides with average molecular weights of, respectively, 204.6 and 202.8kDa, and composed of glucose, mannose and galactose with molar ratios of 18.21:78.76:3.03 and 12.92:30.89:56.19, respectively.	Mannose	148-155	RALBP1 associated Eps domain containing 1	Homo sapiens	4-21
24806833-6	2014	The average adhesion energy per mannose ligand on the probe was 5 kJ/mol, suggesting that a fraction of mannose ligands presented on the SCP bound to the receptor surface.	Mannose	32-39	urocortin 3	Homo sapiens	137-140
24806833-6	2014	The average adhesion energy per mannose ligand on the probe was 5 kJ/mol, suggesting that a fraction of mannose ligands presented on the SCP bound to the receptor surface.	Mannose	104-111	urocortin 3	Homo sapiens	137-140
24631031-8	2014	This divergence was due to a mannose-dependent lactoferrin binding to the bacterial type 1 pili and consequent bacterial aggregation on the intestinal epithelial cell surface.	Mannose	29-36	lactotransferrin	Bos taurus	47-58
24680813-2	2014	The polysaccharide moiety of MT2-A was mainly composed of mannose and trace amount of glucose.	Mannose	58-65	metallothionein 2A	Homo sapiens	29-34
24519966-3	2014	ERManI removes the alpha1,2-linked mannose of the B-chain from properly folded ER glycoproteins, whereas two or more alpha1,2-linked mannose residues are sequentially trimmed from improperly folded glycoproteins so they are recognized by a complex that mediates ER-associated degradation (ERAD).	Mannose	35-42	mannosidase alpha class 1B member 1	Homo sapiens	0-6
24519966-8	2014	The ability of hERManI to remove mannose residues from GlcMan9GlcNAc2 in model glycoproteins, such as Aspergillus oryzae beta-galactosidase and chicken immunoglobulin Y (IgY), was markedly augmented when glycoproteins were denatured.	Mannose	33-40	mannosidase alpha class 1B member 1	Homo sapiens	15-22
24579693-0	2014	Tumour-associated macrophages targeted transfection with NF-kappaB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice.	Mannose	73-80	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	57-66
24579693-2	2014	As NF-kappaB is a key regulator of macrophage polarization, we developed an in vivo TAM-targeting delivery system that combines mannose-modified bubble liposomes/NF-kappaB decoy complexes (Man-PEG bubble lipoplexes) and ultrasound (US) exposure.	Mannose	128-135	nuclear factor kappa B subunit 1	Homo sapiens	3-12
24828077-0	2014	Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV.	Mannose	62-69	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	79-84
24632372-2	2014	HIV-1 gp120 high-mannose has been attributed immunosuppressive roles in human myeloid DCs, but no receptors for high-mannose have so far been reported on human pDCs.	Mannose	17-24	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	6-11
24884664-0	2014	Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain.	Mannose	55-64	interleukin 10	Rattus norvegicus	32-37
24884664-11	2014	mannose pretreatment significantly and dose-dependently prolonged pDNA-IL-10 pain suppressive effects, reduced spinal IL-1beta and enhanced spinal and dorsal root ganglia IL-10 immunoreactivity.	Mannose	0-7	interleukin 10	Rattus norvegicus	66-76
24884664-11	2014	mannose pretreatment significantly and dose-dependently prolonged pDNA-IL-10 pain suppressive effects, reduced spinal IL-1beta and enhanced spinal and dorsal root ganglia IL-10 immunoreactivity.	Mannose	0-7	interleukin 1 beta	Rattus norvegicus	118-126
24884664-11	2014	mannose pretreatment significantly and dose-dependently prolonged pDNA-IL-10 pain suppressive effects, reduced spinal IL-1beta and enhanced spinal and dorsal root ganglia IL-10 immunoreactivity.	Mannose	0-7	interleukin 10	Rattus norvegicus	71-76
24884664-12	2014	Macrophages exposed to D-mannose revealed reduced proinflammatory TNF-alpha, IL-1beta, and nitric oxide, and increased IL-10 protein release, while IL-4 revealed no improvement in transgene uptake.	Mannose	23-32	tumor necrosis factor	Rattus norvegicus	66-75
24884664-12	2014	Macrophages exposed to D-mannose revealed reduced proinflammatory TNF-alpha, IL-1beta, and nitric oxide, and increased IL-10 protein release, while IL-4 revealed no improvement in transgene uptake.	Mannose	23-32	interleukin 1 beta	Rattus norvegicus	77-85
24884664-12	2014	Macrophages exposed to D-mannose revealed reduced proinflammatory TNF-alpha, IL-1beta, and nitric oxide, and increased IL-10 protein release, while IL-4 revealed no improvement in transgene uptake.	Mannose	23-32	interleukin 10	Rattus norvegicus	119-124
24884664-13	2014	Separately, D-mannose dramatically increased pDNA-derived IL-10 protein release in culture supernatants.	Mannose	12-21	interleukin 10	Rattus norvegicus	58-63
24884664-15	2014	co-injection of mannose with a 25-fold lower pDNA-IL-10 dose produced prolonged pain suppression in neuropathic rats.	Mannose	16-23	interleukin 10	Rattus norvegicus	45-55
24884664-16	2014	CONCLUSIONS: Peri-spinal treatment with D-mannose may optimize naked pDNA-IL-10 transgene uptake for suppression of allodynia, and is a novel approach to tune spinal immune cells toward pro-phagocytic phenotype for improved non-viral gene therapy.	Mannose	40-49	interleukin 10	Rattus norvegicus	69-79
24166050-6	2014	In particular, archazolid induced the secretion of the proforms of cathepsin B and D. Archazolid treatment abrogates the cathepsin B maturation process leading to reduced intracellular mature cathepsin B protein abundance and finally decreased cathepsin B activity, by inhibiting mannose-6-phoshate receptor-dependent trafficking.	Mannose	280-287	cathepsin B	Mus musculus	67-78
24166050-6	2014	In particular, archazolid induced the secretion of the proforms of cathepsin B and D. Archazolid treatment abrogates the cathepsin B maturation process leading to reduced intracellular mature cathepsin B protein abundance and finally decreased cathepsin B activity, by inhibiting mannose-6-phoshate receptor-dependent trafficking.	Mannose	280-287	cathepsin B	Mus musculus	121-132
24166050-6	2014	In particular, archazolid induced the secretion of the proforms of cathepsin B and D. Archazolid treatment abrogates the cathepsin B maturation process leading to reduced intracellular mature cathepsin B protein abundance and finally decreased cathepsin B activity, by inhibiting mannose-6-phoshate receptor-dependent trafficking.	Mannose	280-287	cathepsin B	Mus musculus	121-132
24166050-6	2014	In particular, archazolid induced the secretion of the proforms of cathepsin B and D. Archazolid treatment abrogates the cathepsin B maturation process leading to reduced intracellular mature cathepsin B protein abundance and finally decreased cathepsin B activity, by inhibiting mannose-6-phoshate receptor-dependent trafficking.	Mannose	280-287	cathepsin B	Mus musculus	121-132
24917928-0	2014	Changes in fetal mannose and other carbohydrates induced by a maternal insulin infusion in pregnant sheep.	Mannose	17-24	LOC105613195	Ovis aries	71-78
24917928-3	2014	In pregnant sheep, maternal insulin infusions were used to reduce glucose supply to the fetus for both short (2-wk) and long (8-wk) durations to test the hypothesis that a maternal insulin infusion would suppress fetal mannose and inositol concentrations.	Mannose	219-226	LOC105613195	Ovis aries	181-188
24917928-5	2014	RESULTS: A maternal insulin infusion resulted in lower maternal (50%, P &lt; 0.01) and fetal (35-45%, P &lt; 0.01) mannose concentrations, which were highly correlated (r(2) = 0.69, P &lt; 0.01).	Mannose	115-122	LOC105613195	Ovis aries	20-27
24917928-6	2014	A fetal insulin infusion resulted in a 50% reduction of fetal mannose (P &lt; 0.05).	Mannose	62-69	LOC105613195	Ovis aries	8-15
24515582-5	2014	Mannose- or galactose-displaying HFPCNs recognize and tightly bind to DC-SIGN or ASGP-R lectins on the surface of the mammalian cells, DCEK or HepG2 cells.	Mannose	0-7	asialoglycoprotein receptor 1	Homo sapiens	81-87
25199249-10	2014	Treatment with alpha-1,2-mannosidase converted both Man,GlcNAc2 and Man,GlcNAc2 products to a single Man3GlcNAc, form, indicating that the additional mannose on Man,GlcNAc, product comes from an alpha-1, 2 modification.	Mannose	150-157	mannosidase alpha class 1A member 2	Homo sapiens	15-36
24573086-2	2014	The human SGLT5 (hSGLT5), in particular, is localized in the kidney were it is responsible for mannose and fructose reabsorption from the glomerular filtrate as confirmed by more recent studies on hSGLT5 knockout mice.	Mannose	95-102	solute carrier family 5 member 10	Homo sapiens	10-15
24573086-2	2014	The human SGLT5 (hSGLT5), in particular, is localized in the kidney were it is responsible for mannose and fructose reabsorption from the glomerular filtrate as confirmed by more recent studies on hSGLT5 knockout mice.	Mannose	95-102	solute carrier family 5 member 10	Homo sapiens	17-23
24502338-4	2014	We demonstrate here that in RAW264.7 murine macrophages, Hyal-1 is synthesized as a glycosylated precursor that is only weakly mannose 6-phosphorylated.	Mannose	127-134	hyaluronoglucosaminidase 1	Mus musculus	57-63
24580381-3	2014	A mannose-modified LCP NP delivered both tumor antigen (Trp 2 peptide) and adjuvant (CpG oligonucleotide) to the dendritic cells and elicited a potent, systemic immune response regardless of the existence or the stage of tumors in the host.	Mannose	2-9	tRNA-Pro (anticodon AGG) 2-6	Homo sapiens	56-61
24627495-3	2014	The suspected role for the MAN1B1 gene product MAN1B1, also known as ER mannosidase I, is to function within the ER similar to the yeast ortholog Mns1p, which removes a terminal mannose unit to initiate a glycan-based ER-associated degradation (ERAD) signal.	Mannose	178-185	mannosidase alpha class 1B member 1	Homo sapiens	27-33
24627495-3	2014	The suspected role for the MAN1B1 gene product MAN1B1, also known as ER mannosidase I, is to function within the ER similar to the yeast ortholog Mns1p, which removes a terminal mannose unit to initiate a glycan-based ER-associated degradation (ERAD) signal.	Mannose	178-185	mannosidase alpha class 1B member 1	Homo sapiens	47-53
24627495-3	2014	The suspected role for the MAN1B1 gene product MAN1B1, also known as ER mannosidase I, is to function within the ER similar to the yeast ortholog Mns1p, which removes a terminal mannose unit to initiate a glycan-based ER-associated degradation (ERAD) signal.	Mannose	178-185	mannosyl-oligosaccharide 1,2-alpha-mannosidase	Saccharomyces cerevisiae S288C	146-151
23581857-3	2014	In this work, we have investigated ARSA dynamics employing molecular dynamics simulations in response to (1) different pH"s, as, beyond its natural lysossomal environment, it has been recently identified in cytoplasmatic medium and (2) glycan occupancies, including its normal glycosylation state, presenting three high mannose-type oligosaccharides.	Mannose	320-327	arylsulfatase A	Homo sapiens	35-39
24713873-7	2014	We found that two AMPA receptor subunits, GluA2 and GluA4, are sensitive to deglycosylation with Endo H and PNGase F. When we enriched for glycosylated proteins using lectin binding assays, we found that all four AMPA receptor subunits are glycosylated, and were predominantly recognized by lectins that bind to glucose or mannose, N-acetylglucosamine (GlcNAc), or 1-6alphafucose.	Mannose	323-330	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	42-47
24713873-7	2014	We found that two AMPA receptor subunits, GluA2 and GluA4, are sensitive to deglycosylation with Endo H and PNGase F. When we enriched for glycosylated proteins using lectin binding assays, we found that all four AMPA receptor subunits are glycosylated, and were predominantly recognized by lectins that bind to glucose or mannose, N-acetylglucosamine (GlcNAc), or 1-6alphafucose.	Mannose	323-330	glutamate ionotropic receptor AMPA type subunit 4	Homo sapiens	52-57
24421398-0	2014	Mannose supplements induce embryonic lethality and blindness in phosphomannose isomerase hypomorphic mice.	Mannose	0-7	mannose phosphate isomerase	Mus musculus	64-88
24415556-3	2014	UGGT1 is a well-documented enzyme which functions as a folding sensor in the endoplasmic reticulum, by the virtue of its ability to transfer a glucose residue to non-glucosylated high-mannose-type glycans of immature glycoproteins exhibiting non-native conformation.	Mannose	184-191	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	0-5
24556146-0	2014	Monovalent mannose-based DC-SIGN antagonists: targeting the hydrophobic groove of the receptor.	Mannose	11-18	CD209 molecule	Homo sapiens	25-32
24474243-8	2014	Since phosphomannose isomerase (MPI)-CDG patients and their cells improve glycosylation when given mannose, we provided MPI-deficient mice with mannose-supplemented water for 7 days.	Mannose	13-20	mannose phosphate isomerase	Homo sapiens	32-35
24474243-8	2014	Since phosphomannose isomerase (MPI)-CDG patients and their cells improve glycosylation when given mannose, we provided MPI-deficient mice with mannose-supplemented water for 7 days.	Mannose	99-106	mannose phosphate isomerase	Mus musculus	6-30
24474243-8	2014	Since phosphomannose isomerase (MPI)-CDG patients and their cells improve glycosylation when given mannose, we provided MPI-deficient mice with mannose-supplemented water for 7 days.	Mannose	99-106	mannose phosphate isomerase	Homo sapiens	32-35
24556146-3	2014	We report the design and synthesis of d-mannose-based DC-SIGN antagonists bearing diaryl substituted 1,3-diaminopropanol or glycerol moieties incorporated to target the hydrophobic groove of the receptor.	Mannose	38-47	CD209 molecule	Homo sapiens	54-61
24658372-2	2014	Ad.IL3 was further engineered to harbor gene encoding manganese superoxide dismutase (MnSOD) or mannose-binding plant lectin Pinellia pedatisecta agglutinin (PPA), forming Ad.IL3-MnSOD and Ad.IL3-PPA.	Mannose	96-103	interleukin 3	Homo sapiens	3-6
24469452-4	2014	F-box only protein 2 (Fbxo2), a neuron-enriched ubiquitin ligase substrate adaptor that preferentially binds high-mannose glycans on glycoproteins, was previously implicated in APP processing by facilitating the degradation of the APP-cleaving beta-secretase, beta-site APP-cleaving enzyme.	Mannose	114-121	F-box protein 2	Mus musculus	0-20
24658372-2	2014	Ad.IL3 was further engineered to harbor gene encoding manganese superoxide dismutase (MnSOD) or mannose-binding plant lectin Pinellia pedatisecta agglutinin (PPA), forming Ad.IL3-MnSOD and Ad.IL3-PPA.	Mannose	96-103	interleukin 3	Homo sapiens	175-178
24658372-2	2014	Ad.IL3 was further engineered to harbor gene encoding manganese superoxide dismutase (MnSOD) or mannose-binding plant lectin Pinellia pedatisecta agglutinin (PPA), forming Ad.IL3-MnSOD and Ad.IL3-PPA.	Mannose	96-103	interleukin 3	Homo sapiens	175-178
24407290-1	2014	Mannose in N-glycans is derived from glucose through phosphomannose isomerase (MPI, Fru-6-P   Man-6-P) whose deficiency causes a congenital disorder of glycosylation (CDG)-Ib (MPI-CDG).	Mannose	0-7	mannose phosphate isomerase	Homo sapiens	79-82
24407290-1	2014	Mannose in N-glycans is derived from glucose through phosphomannose isomerase (MPI, Fru-6-P   Man-6-P) whose deficiency causes a congenital disorder of glycosylation (CDG)-Ib (MPI-CDG).	Mannose	0-7	mannose phosphate isomerase	Homo sapiens	176-179
24469452-4	2014	F-box only protein 2 (Fbxo2), a neuron-enriched ubiquitin ligase substrate adaptor that preferentially binds high-mannose glycans on glycoproteins, was previously implicated in APP processing by facilitating the degradation of the APP-cleaving beta-secretase, beta-site APP-cleaving enzyme.	Mannose	114-121	F-box protein 2	Mus musculus	22-27
24584735-3	2014	Both WT- and E3-defective C329S-HRD1 decreased the level of high mannose form of ABCG8, a protein that heterodimerizes with ABCG5 to control sterol balance.	Mannose	65-72	synoviolin 1	Homo sapiens	32-36
24584735-3	2014	Both WT- and E3-defective C329S-HRD1 decreased the level of high mannose form of ABCG8, a protein that heterodimerizes with ABCG5 to control sterol balance.	Mannose	65-72	ATP binding cassette subfamily G member 8	Homo sapiens	81-86
24584735-3	2014	Both WT- and E3-defective C329S-HRD1 decreased the level of high mannose form of ABCG8, a protein that heterodimerizes with ABCG5 to control sterol balance.	Mannose	65-72	ATP binding cassette subfamily G member 5	Homo sapiens	124-129
24491912-1	2014	The mannose-binding C-type lectin receptor SIGNR1 appears to be a structural and functional murine homologue of human DC-SIGN, but expression of SIGNR1 and its function in induction of immune responses in dendritic cell (DC) lineages remains unclear.	Mannose	4-11	CD209b antigen	Mus musculus	43-49
24266751-1	2014	Enzyme replacement therapy for MPS IIIB (mucopolysaccharidosis type IIIB; also known as Sanfilippo B syndrome) has been hindered by inadequate mannose 6 phosphorylation and cellular uptake of rhNAGLU (recombinant human alpha-N-acetylglucosaminidase).	Mannose	143-150	N-acetyl-alpha-glucosaminidase	Homo sapiens	31-39
24352591-4	2014	The O-linked HNK-1 epitope on phosphacan almost disappeared due to the knockout of protein O-mannose beta1,2-N-acetylglucosaminyltransferase 1, an N-acetylglucosaminyltransferase essential for O-mannose-linked glycan synthesis, indicating that the reducing terminal of the O-linked HNK-1 is mannose.	Mannose	93-100	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	Mus musculus	13-18
24221747-4	2014	Mammary glands mainly express GLUT1 and GLUT8, and GLUT1 is the predominant isoform with a Km of ~10 mM and transport activity for mannose and galactose in addition to glucose.	Mannose	131-138	solute carrier family 2 member 1	Homo sapiens	51-56
24383474-9	2014	Among Chinese, we identified single-nucleotide polymorphisms associated with upper-lower lobe ratio near DHX15 (rs7698250; P = 1.8 x 10(-10); MAF, 2.7%) and MGAT5B (rs7221059; P = 2.7 x 10(-8); MAF, 2.6%), which acts on alpha-linked mannose.	Mannose	233-240	DEAH-box helicase 15	Homo sapiens	105-110
24383474-9	2014	Among Chinese, we identified single-nucleotide polymorphisms associated with upper-lower lobe ratio near DHX15 (rs7698250; P = 1.8 x 10(-10); MAF, 2.7%) and MGAT5B (rs7221059; P = 2.7 x 10(-8); MAF, 2.6%), which acts on alpha-linked mannose.	Mannose	233-240	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	157-163
24361341-5	2014	Based on differential sensitivity to glycosidases, the doublet was identified as two high-mannose-type glycoforms of NOX1, whereas the broad band represented NOX1 with complex-type N-linked oligosaccharides.	Mannose	90-97	NADPH oxidase 1	Mus musculus	117-121
24239607-3	2014	The carbohydrate specificity of dendritic cell immunoreceptor (DCIR), another DC-expressed lectin, was still debated, but we have recently confirmed DCIR as mannose/fucose-binding lectin.	Mannose	157-164	C-type lectin domain family 4 member A	Homo sapiens	32-61
24239607-3	2014	The carbohydrate specificity of dendritic cell immunoreceptor (DCIR), another DC-expressed lectin, was still debated, but we have recently confirmed DCIR as mannose/fucose-binding lectin.	Mannose	157-164	C-type lectin domain family 4 member A	Homo sapiens	63-67
24239607-3	2014	The carbohydrate specificity of dendritic cell immunoreceptor (DCIR), another DC-expressed lectin, was still debated, but we have recently confirmed DCIR as mannose/fucose-binding lectin.	Mannose	157-164	C-type lectin domain family 4 member A	Homo sapiens	149-153
24576294-2	2014	There is a protein called mannose binding lectin (MBL) that was reported to play an important role in innate immunity.	Mannose	26-33	mannose binding lectin 2	Homo sapiens	50-53
24649404-0	2014	Ursolic acid, a natural pentacyclic triterpenoid, inhibits intracellular trafficking of proteins and induces accumulation of intercellular adhesion molecule-1 linked to high-mannose-type glycans in the endoplasmic reticulum.	Mannose	174-181	intercellular adhesion molecule 1	Homo sapiens	125-158
24649404-7	2014	Ursolic acid induced the accumulation of ICAM-1 in the endoplasmic reticulum, which was linked mainly to high-mannose-type glycans.	Mannose	110-117	intercellular adhesion molecule 1	Homo sapiens	41-47
24649404-9	2014	Thus, our results reveal that ursolic acid inhibits intracellular trafficking of proteins and induces the accumulation of ICAM-1 linked to high-mannose-type glycans in the endoplasmic reticulum.	Mannose	144-151	intercellular adhesion molecule 1	Homo sapiens	122-128
24498414-3	2014	VIP36 specifically interacts with the alpha1,2-linked D1 mannosyl arm without terminal glucosylation, while ERGIC-53 shows a broader specificity and lower binding affinity to the high-mannose-type oligosaccharides, irrespective of the presence or absence of the non-reducing terminal glucose residue at the D1 arm.	Mannose	184-191	lectin, mannose binding 1	Homo sapiens	108-116
24498414-4	2014	In this study, we determined the crystal structure of ERGIC-53-CRD in complex with their binding partner, MCFD2 and the alpha1,2 mannotriose which corresponds to the trisaccharide of the D1 arm of high-mannose-type glycans.	Mannose	202-209	lectin, mannose binding 1	Homo sapiens	54-62
24498414-4	2014	In this study, we determined the crystal structure of ERGIC-53-CRD in complex with their binding partner, MCFD2 and the alpha1,2 mannotriose which corresponds to the trisaccharide of the D1 arm of high-mannose-type glycans.	Mannose	202-209	multiple coagulation factor deficiency 2, ER cargo receptor complex subunit	Homo sapiens	106-111
24491912-1	2014	The mannose-binding C-type lectin receptor SIGNR1 appears to be a structural and functional murine homologue of human DC-SIGN, but expression of SIGNR1 and its function in induction of immune responses in dendritic cell (DC) lineages remains unclear.	Mannose	4-11	CD209b antigen	Mus musculus	145-151
24491912-8	2014	Thus, low levels of SIGNR1 expressed on mouse peritoneal phagocytic cells with an immature DC-like phenotype are primarily involved in uptake of mannose- or fucose-decorated particles, and this uptake leads to cell maturation.	Mannose	145-152	CD209b antigen	Mus musculus	20-26
24498414-4	2014	In this study, we determined the crystal structure of ERGIC-53-CRD in complex with their binding partner, MCFD2 and the alpha1,2 mannotriose which corresponds to the trisaccharide of the D1 arm of high-mannose-type glycans.	Mannose	202-209	adrenoceptor alpha 1D	Homo sapiens	120-128
24124125-6	2014	The OVA-mannose group also had less histamine, MMCP-1, specific IgG, IL-4 and IL-17, and more IL-12p70 (p &lt;= 0.05).	Mannose	8-15	mast cell protease 1	Mus musculus	47-53
24321858-0	2014	Mannose-binding lectin genetic analysis: possible protective role of the HYPA haplotype in the development of recurrent urinary tract infections in men.	Mannose	0-7	pre-mRNA processing factor 40 homolog A	Homo sapiens	73-77
24391218-1	2014	Mannan (mannose)-binding protein (MBP) is a C-type serum lectin that plays a key role in innate immunity.	Mannose	8-15	myelin basic protein	Homo sapiens	34-37
24509175-0	2014	Targeted siRNA silencing of indoleamine 2, 3-dioxygenase in antigen-presenting cells using mannose-conjugated liposomes: a novel strategy for treatment of melanoma.	Mannose	91-98	indoleamine 2,3-dioxygenase 1	Homo sapiens	28-56
24124125-6	2014	The OVA-mannose group also had less histamine, MMCP-1, specific IgG, IL-4 and IL-17, and more IL-12p70 (p &lt;= 0.05).	Mannose	8-15	interleukin 4	Mus musculus	69-73
24391218-2	2014	MBP forms large multimers (200-600 kDa) and exhibits broad specificity for mannose, N-acetylglucosamine, and fucose.	Mannose	75-82	myelin basic protein	Homo sapiens	0-3
24124125-6	2014	The OVA-mannose group also had less histamine, MMCP-1, specific IgG, IL-4 and IL-17, and more IL-12p70 (p &lt;= 0.05).	Mannose	8-15	interleukin 17A	Mus musculus	78-83
24295106-8	2014	Downregulation of Man1alpha1 and Mgat1 in LIM1215 also coincided with the higher degree of incomplete N-glycan processing and accumulation of high mannose type structures as well as bisecting N-glycans when compared to the other two cell lines.	Mannose	147-154	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	33-38
24365146-4	2014	In the absence of p22(phox), Nox1 is transported to the plasma membrane mainly as a form with high mannose N-glycans, although their conversion into complex N-glycans is induced by expression of p22(phox).	Mannose	99-106	NADPH oxidase 1	Homo sapiens	29-33
24334224-4	2014	Our results demonstrated that Thr134, the equivalent O-linked glycosylation site found on endogenous human G-CSF, is the only site modified with a single mannose, allowing glycoengineered P. pastoris to be used as a viable production platform for therapeutic rhG-CSF.	Mannose	154-161	colony stimulating factor 3	Homo sapiens	107-112
24336744-3	2014	SGP-2 is mainly composed of glucose, galactose, mannose, arabinose and galacturonic acid in a molar ratio of 12.19 : 8.68 : 6.03 : 1.00 : 15.24.	Mannose	48-55	clusterin	Homo sapiens	0-5
24274513-4	2014	HMP-1 and HMP-2 were mainly composed of arabinose, galactose, glucose and mannose with the molecular weight of 133 and 100 kDa, respectively.	Mannose	74-81	inner membrane mitochondrial protein	Homo sapiens	0-3
24274513-4	2014	HMP-1 and HMP-2 were mainly composed of arabinose, galactose, glucose and mannose with the molecular weight of 133 and 100 kDa, respectively.	Mannose	74-81	inner membrane mitochondrial protein	Homo sapiens	10-13
24156700-3	2014	LSECtin, a Ca2+-dependent C-type lectin, interacts with mannose, NAcGlc and fucose.	Mannose	56-63	C-type lectin domain family 4 member G	Homo sapiens	0-7
24178944-2	2014	N-acetylglucosaminyltransferase I (GlcNAc-TI) first catalyzes addition of GlcNAc in beta1-2 linkage to the Manalpha1-3-R terminus of the five-mannose structure.	Mannose	142-149	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	35-44
24178944-2	2014	N-acetylglucosaminyltransferase I (GlcNAc-TI) first catalyzes addition of GlcNAc in beta1-2 linkage to the Manalpha1-3-R terminus of the five-mannose structure.	Mannose	142-149	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	84-91
24134734-3	2013	We have shown that, even as single molecules, these compounds efficiently target mannose-binding lectins, such as DC-specific ICAM-3-grabbing nonintegrin (DC-SIGN) important for HIV-1 transmission.	Mannose	81-88	CD209 molecule	Homo sapiens	155-162
24174266-0	2014	Facile removal of high mannose structures prior to extracting complex type N-glycans from de-N-glycosylated peptides retained by C18 solid phase to allow more efficient glycomic mapping.	Mannose	23-30	Bardet-Biedl syndrome 9	Homo sapiens	129-132
24174266-3	2014	Capitalizing on an initial observation that only high mannose type structures were recovered in the flow-through fraction when peptide-N-glycosidase F digested peptides were passed through a C18 cartridge in 0.1% formic acid, we demonstrated here that native complex type N-glycans can be retained by C18 cartridge and to be efficiently separated from both the smaller high mannose type structures, as well as de-N-glycosylated peptides by stepwise elution with increasing ACN concentration.	Mannose	54-61	Bardet-Biedl syndrome 9	Homo sapiens	191-194
24174266-3	2014	Capitalizing on an initial observation that only high mannose type structures were recovered in the flow-through fraction when peptide-N-glycosidase F digested peptides were passed through a C18 cartridge in 0.1% formic acid, we demonstrated here that native complex type N-glycans can be retained by C18 cartridge and to be efficiently separated from both the smaller high mannose type structures, as well as de-N-glycosylated peptides by stepwise elution with increasing ACN concentration.	Mannose	54-61	Bardet-Biedl syndrome 9	Homo sapiens	301-304
24174266-3	2014	Capitalizing on an initial observation that only high mannose type structures were recovered in the flow-through fraction when peptide-N-glycosidase F digested peptides were passed through a C18 cartridge in 0.1% formic acid, we demonstrated here that native complex type N-glycans can be retained by C18 cartridge and to be efficiently separated from both the smaller high mannose type structures, as well as de-N-glycosylated peptides by stepwise elution with increasing ACN concentration.	Mannose	374-381	Bardet-Biedl syndrome 9	Homo sapiens	191-194
23898885-0	2013	Characterization and downstream mannose phosphorylation of human recombinant alpha-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds.	Mannose	32-39	alpha-L-iduronidase	Homo sapiens	77-96
23898885-5	2013	The N-glycan profile showed that cgl-derived IDUA contained predominantly high-mannose-type N-glycans (94.5%), and the residual complex/hybrid N-glycan-containing enzyme was efficiently removed by an additional affinity chromatography step.	Mannose	79-86	alpha-L-iduronidase	Homo sapiens	45-49
24198161-6	2014	The up-regulated genes were mainly enriched in the TGF-beta and cell cycle signaling pathways and down-regulated genes were mainly enriched in the insulin-mediated signal pathway, metabolic pathway of fructose and mannose, and glycolysis/gluconeogenesis pathway.	Mannose	214-221	transforming growth factor beta 1	Homo sapiens	51-59
24198161-6	2014	The up-regulated genes were mainly enriched in the TGF-beta and cell cycle signaling pathways and down-regulated genes were mainly enriched in the insulin-mediated signal pathway, metabolic pathway of fructose and mannose, and glycolysis/gluconeogenesis pathway.	Mannose	214-221	insulin	Homo sapiens	147-154
24217250-2	2013	Langerin binds a diverse range of carbohydrates including high mannose structures, fucosylated blood group antigens, and glycans with terminal 6-sulfated galactose.	Mannose	63-70	CD207 molecule	Homo sapiens	0-8
24358298-6	2013	Expectedly, the solubility of Tat-LSECtin-CRD significantly increased compared to Tat-free LSECtin-CRD (**p &lt; 0.01) with prolonged time, and the Tat-LSECtin-CRD had a significant mannose-binding activity.	Mannose	182-189	C-type lectin domain family 4 member G	Homo sapiens	34-41
24697100-9	2013	CONCLUSION: Combined deletion of tandem repeats B, C and D adjacent to the 3"-terminal of FLO1 increases the conformation stability of flocculin in response to changes of pH, temperature or concentration of mannose in environment, but does not influence the other characteristics of flocculation.	Mannose	207-214	flocculin FLO1	Saccharomyces cerevisiae S288C	90-94
24134734-9	2013	We present an interaction model between DC-SIGN and conjugates-either single molecules, micelles, or polymers-that highlights that the most effective interactions by dynamic micelles involve both mannose heads and lipid chains.	Mannose	196-203	CD209 molecule	Homo sapiens	40-47
24113656-0	2013	O-glycosylation of the non-canonical T-cadherin from rabbit skeletal muscle by single mannose residues.	Mannose	86-93	cadherin 13	Homo sapiens	37-47
24205138-7	2013	Purified serglycin inhibited early steps of both the classical and the lectin pathways of complement by binding to C1q and mannose-binding lectin.	Mannose	123-130	serglycin	Homo sapiens	9-18
23865867-0	2013	Variant MBL2 genotypes producing low mannose-binding lectin may increase risk of Bacillus Calmette-Guerin osteitis in vaccinated newborns.	Mannose	37-44	mannose binding lectin 2	Homo sapiens	8-12
23865867-1	2013	AIM: The aim of this study was to evaluate whether mannose-binding lectin (MBL) plays a role in the development of osteitis after Bacillus Calmette-Guerin (BCG) vaccination as a newborn.	Mannose	51-58	mannose binding lectin 2	Homo sapiens	75-78
24018285-3	2013	The CIAS1 and IL1RN polymorphisms were associated with altered interleukin-1beta serum levels; the MBL2 polymorphism resulted in a decreased serum mannose-binding lectin concentration.	Mannose	147-154	mannose binding lectin 2	Homo sapiens	99-103
24043630-0	2013	The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein.	Mannose	154-161	activating transcription factor 6 beta	Gallus gallus	41-45
24043630-9	2013	In addition, endogenous ATF6 was markedly stabilized in wild-type cells treated with kifunensine, an inhibitor of alpha1,2-mannosidase in the ER, indicating that degradation of ATF6 requires proper mannose trimming.	Mannose	198-205	activating transcription factor 6 beta	Gallus gallus	24-28
24074568-3	2013	Sequence analysis of gp120 showed that most had deletions of 1 to 5 mannose-rich glycans.	Mannose	68-75	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	21-26
23585333-1	2013	Tandem assays of protein and glucose in combination with mannose-functionalized Fe3 O4 @SiO2 and Ag@SiO2 tag particles have promising potential in effective magnetic separation and highly sensitive and selective SERS assays of biomaterials.	Mannose	57-64	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	212-216
23986440-7	2013	When expressed in human cells, ARSK was detected as a 68-kDa glycoprotein carrying at least four N-glycans of both the complex and high-mannose type.	Mannose	136-143	arylsulfatase family member K	Homo sapiens	31-35
23980545-1	2013	The glycosylation of recombinant beta-glucocerebrosidase, and in particular the exposure of mannose residues, has been shown to be a key factor in the success of ERT (enzyme replacement therapy) for the treatment of GD (Gaucher disease).	Mannose	92-99	glucosylceramidase beta	Homo sapiens	33-56
23861212-2	2013	The mannose binding lectin (MBL) and its associated serine protease type 2 (MASP-2) promote the activation of the lectin pathway of the complement system.	Mannose	4-11	mannose binding lectin 2	Homo sapiens	28-31
23861212-2	2013	The mannose binding lectin (MBL) and its associated serine protease type 2 (MASP-2) promote the activation of the lectin pathway of the complement system.	Mannose	4-11	MBL associated serine protease 2	Homo sapiens	76-82
23820013-6	2013	In vitro gene silencing experiments revealed that TPP-PPM/TNF-alpha siRNA NPs with a weight ratio of 40:1 showed the most efficient inhibition of the expression and secretion of TNF-alpha (approximately 69.9%, which was comparable to the 71.4% obtained using OF/siRNA NPs), and its RNAi efficiency was highly inhibited in the presence of mannose (20 mm).	Mannose	338-345	tumor necrosis factor	Homo sapiens	58-67
23820013-6	2013	In vitro gene silencing experiments revealed that TPP-PPM/TNF-alpha siRNA NPs with a weight ratio of 40:1 showed the most efficient inhibition of the expression and secretion of TNF-alpha (approximately 69.9%, which was comparable to the 71.4% obtained using OF/siRNA NPs), and its RNAi efficiency was highly inhibited in the presence of mannose (20 mm).	Mannose	338-345	tumor necrosis factor	Homo sapiens	178-187
24033743-7	2013	GGTA1/CMAH knockout pig samples had increased relative amounts of high-mannose, incomplete, and xylosylated N-linked glycans.	Mannose	71-78	N-acetyllactosaminide alpha-1,3-galactosyltransferase	Sus scrofa	0-5
23852824-9	2013	FV and FVIII likely bind LMAN1 through the high-mannose N-linked glycans under the higher Ca2+ conditions in the ER and dissociate in the lower Ca2+ environment of the ER-Golgi intermediate compartment.	Mannose	48-55	coagulation factor VIII	Homo sapiens	7-12
23852824-9	2013	FV and FVIII likely bind LMAN1 through the high-mannose N-linked glycans under the higher Ca2+ conditions in the ER and dissociate in the lower Ca2+ environment of the ER-Golgi intermediate compartment.	Mannose	48-55	lectin, mannose binding 1	Homo sapiens	25-30
24033743-7	2013	GGTA1/CMAH knockout pig samples had increased relative amounts of high-mannose, incomplete, and xylosylated N-linked glycans.	Mannose	71-78	cytidine monophospho-N-acetylneuraminic acid hydroxylase	Sus scrofa	6-10
23824149-4	2013	The apparent dissociation constant between GOx@Au probes and Con A was detected to be 1.64 nM and was approximately 5 orders of magnitude smaller than that of mannose and Con A, which would arise from the multivalent effect between the probe and Con A.	Mannose	159-166	hydroxyacid oxidase 1	Homo sapiens	43-46
23820740-8	2013	The NR1, NR2A, NR2B, GluR6, and KA2 subunits were all sensitive to treatment with Endo H and PNGase F. The GluR6 KA receptor subunit was significantly more sensitive to Endo H-mediated deglycosylation in schizophrenia, suggesting a larger molecular mass of N-linked high mannose and/or hybrid sugars on GluR6.	Mannose	271-278	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	4-7
23929950-4	2013	Furthermore, we identified SGK196 as an atypical kinase that phosphorylated the 6-position of O-mannose, specifically after the mannose had been modified by both GTDC2 and B3GALNT2.	Mannose	96-103	protein O-mannose kinase	Homo sapiens	27-33
23929950-4	2013	Furthermore, we identified SGK196 as an atypical kinase that phosphorylated the 6-position of O-mannose, specifically after the mannose had been modified by both GTDC2 and B3GALNT2.	Mannose	96-103	protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)	Homo sapiens	162-167
23929950-4	2013	Furthermore, we identified SGK196 as an atypical kinase that phosphorylated the 6-position of O-mannose, specifically after the mannose had been modified by both GTDC2 and B3GALNT2.	Mannose	96-103	beta-1,3-N-acetylgalactosaminyltransferase 2	Homo sapiens	172-180
23820740-8	2013	The NR1, NR2A, NR2B, GluR6, and KA2 subunits were all sensitive to treatment with Endo H and PNGase F. The GluR6 KA receptor subunit was significantly more sensitive to Endo H-mediated deglycosylation in schizophrenia, suggesting a larger molecular mass of N-linked high mannose and/or hybrid sugars on GluR6.	Mannose	271-278	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	107-112
23740650-1	2013	From the stacks: A novel method for construction of a high-mannose-type glycan library by systematic enzymatic trimming of a single synthetic Man9-based precursor was developed.	Mannose	59-66	mannosidase alpha class 1A member 1	Homo sapiens	142-146
23820740-8	2013	The NR1, NR2A, NR2B, GluR6, and KA2 subunits were all sensitive to treatment with Endo H and PNGase F. The GluR6 KA receptor subunit was significantly more sensitive to Endo H-mediated deglycosylation in schizophrenia, suggesting a larger molecular mass of N-linked high mannose and/or hybrid sugars on GluR6.	Mannose	271-278	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	107-112
23814060-8	2013	CL-L1 showed specific binding to mannose-TSK beads in a Ca(2+)-dependent manner.	Mannose	33-40	collectin subfamily member 10	Homo sapiens	0-5
23814060-8	2013	CL-L1 showed specific binding to mannose-TSK beads in a Ca(2+)-dependent manner.	Mannose	33-40	tsukushi, small leucine rich proteoglycan	Homo sapiens	41-44
23703526-0	2013	Identification of a high-mannose ICAM-1 glycoform: effects of ICAM-1 hypoglycosylation on monocyte adhesion and outside in signaling.	Mannose	25-32	intercellular adhesion molecule 1	Homo sapiens	33-39
23703526-5	2013	Production of exclusively HM-ICAM-1 in cells by alpha-mannosidase inhibition increased monocyte rolling and adhesion compared with mature ICAM-1 consistent with high-mannose epitopes providing leukocyte ligands.	Mannose	166-173	intercellular adhesion molecule 1	Homo sapiens	29-35
23814060-9	2013	This binding could be inhibited by mannose and glucose, but not galactose, indicating that CL-L1 binds via its carbohydrate-recognition domain and has ligand specificity similar to that of mannan-binding lectin.	Mannose	35-42	collectin subfamily member 10	Homo sapiens	91-96
23814060-9	2013	This binding could be inhibited by mannose and glucose, but not galactose, indicating that CL-L1 binds via its carbohydrate-recognition domain and has ligand specificity similar to that of mannan-binding lectin.	Mannose	35-42	mannose binding lectin 2	Homo sapiens	189-210
23709226-6	2013	Our structural data, combined with mutagenesis and in vitro binding assays, define the central mannose-binding site on LMAN1 and pinpoint histidine 178 and glycines 251/252 as critical residues for FV/FVIII binding.	Mannose	95-102	lectin, mannose binding 1	Homo sapiens	119-124
23709226-5	2013	To understand the biochemical basis and regulation of LMAN1 binding to glycoprotein cargo, we solved crystal structures of the LMAN1-CRD bound to Man-alpha-1,2-Man, the terminal carbohydrate moiety of high mannose glycans.	Mannose	206-213	lectin, mannose binding 1	Homo sapiens	54-59
23709226-6	2013	Our structural data, combined with mutagenesis and in vitro binding assays, define the central mannose-binding site on LMAN1 and pinpoint histidine 178 and glycines 251/252 as critical residues for FV/FVIII binding.	Mannose	95-102	coagulation factor VIII	Homo sapiens	201-206
23832207-0	2013	The mannose-specific lectin domains of Flo1p from Saccharomyces cerevisiae and Lg-Flo1p from S. pastorianus: crystallization and preliminary X-ray diffraction analysis of the adhesin-carbohydrate complexes.	Mannose	4-11	flocculin FLO1	Saccharomyces cerevisiae S288C	39-44
23832207-5	2013	Here, the crystallization and preliminary X-ray characterization of the apo form and the mannose complex of N-Flo1p and X-ray analysis of N-Lg-Flo1p crystals soaked in alpha-1,2-mannobiose are reported.	Mannose	89-96	flocculin FLO1	Saccharomyces cerevisiae S288C	110-115
23832207-6	2013	The N-Flo1p crystals diffracted to a resolution of 1.43 A in the case of the apo form and to 2.12 A resolution for the mannose complex.	Mannose	119-126	flocculin FLO1	Saccharomyces cerevisiae S288C	6-11
23884105-4	2013	However, the inhibitory effects by mouse MBL-A or ficolin-A were restored by the addition of mannose or N-acetylglucosamine, respectively.	Mannose	93-100	mannose-binding lectin (protein A) 1	Mus musculus	41-46
23467824-3	2013	By screening a series of peptides derived from the BTV16 VP2 protein and expressed as mannose-binding protein fusions, we determined that the linear epitopes recognized by the VP2-specific MAbs 3 G10 and 2B4 were located within the peptides 34EWSGHDVTEIPNRRMF49 and 540KNEDPYVKRTVKPIRA555, respectively.	Mannose	86-93	VP2	Bluetongue virus	176-179
23884105-4	2013	However, the inhibitory effects by mouse MBL-A or ficolin-A were restored by the addition of mannose or N-acetylglucosamine, respectively.	Mannose	93-100	ficolin A	Mus musculus	50-59
23633012-7	2013	The glycans were enzymatically released, purified, and finally analyzed by MALDI-TOF-MS. To simulate changes to glycan profiles after administration in vivo, a therapeutic antibody was incubated in serum with the enzyme alpha1-2,3 mannosidase to artificially reduce the amount of the high mannose glycoforms.	Mannose	289-296	adrenoceptor alpha 1D	Homo sapiens	220-228
23255139-0	2013	A study on anti-mannose binding lectin (anti-MBL) antibodies and serum MBL levels in Indian systemic lupus erythematosus patients.	Mannose	16-23	mannose-binding lectin family member 3, pseudogene	Homo sapiens	45-48
23613470-7	2013	Mass-spectrometric analyses revealed that Wnt11 is modified with complex/hybrid(Asn40)-, high-mannose(Asn90)- and high-mannose/hybrid(Asn300)-type glycans and that Wnt3a is modified with two high-mannose-type glycans (Asn87 and Asn298).	Mannose	94-101	Wnt family member 11	Homo sapiens	42-47
23613470-7	2013	Mass-spectrometric analyses revealed that Wnt11 is modified with complex/hybrid(Asn40)-, high-mannose(Asn90)- and high-mannose/hybrid(Asn300)-type glycans and that Wnt3a is modified with two high-mannose-type glycans (Asn87 and Asn298).	Mannose	119-126	Wnt family member 11	Homo sapiens	42-47
23613470-7	2013	Mass-spectrometric analyses revealed that Wnt11 is modified with complex/hybrid(Asn40)-, high-mannose(Asn90)- and high-mannose/hybrid(Asn300)-type glycans and that Wnt3a is modified with two high-mannose-type glycans (Asn87 and Asn298).	Mannose	119-126	Wnt family member 11	Homo sapiens	42-47
23586857-5	2013	Detailed analysis of SSO1273, one of the most abundant ABC transporters present in the cell surface fraction of S. solfataricus, revealed a novel glycan structure composed of a branched sulfated heptasaccharide, Hex4(GlcNAc)2 plus sulfoquinovose where Hex is d-mannose and d-glucose.	Mannose	259-268	ABC transporter substrate-binding protein	Saccharolobus solfataricus P2	21-28
23615786-5	2013	The presence of the cell-binding domain sequence and the mannose groups within the transferred molecules was revealed by anti-fibronectin monoclonal antibody immunolabelling and FITC-Concanavalin-A staining, respectively.	Mannose	57-64	fibronectin 1	Mus musculus	126-137
23826391-5	2013	Mannose, galactose, and fructose were able to inhibit FGT-1-mediated 2-deoxy-D-glucose uptake (P &lt; 0.01), indicating that FGT-1 is also able to transport these hexose sugars.	Mannose	0-7	Facilitated glucose transporter protein 1	Caenorhabditis elegans	54-59
23826391-5	2013	Mannose, galactose, and fructose were able to inhibit FGT-1-mediated 2-deoxy-D-glucose uptake (P &lt; 0.01), indicating that FGT-1 is also able to transport these hexose sugars.	Mannose	0-7	Facilitated glucose transporter protein 1	Caenorhabditis elegans	125-130
23528733-3	2013	In the presence of Vpu, only the high mannose form of NTB-A was detectable, suggesting that Vpu prevented the formation of the mature form of NTB-A.	Mannose	38-45	SLAM family member 6	Homo sapiens	54-59
23528733-3	2013	In the presence of Vpu, only the high mannose form of NTB-A was detectable, suggesting that Vpu prevented the formation of the mature form of NTB-A.	Mannose	38-45	SLAM family member 6	Homo sapiens	142-147
23858973-2	2013	In the present work, we report on the development of rifampicin (RIF)-loaded nanoparticles and flower-like polymeric micelles surface-modified with hydrolyzed galatomannan (GalM-h), a polysaccharide of mannose and galactose, two sugars that are recognized by lectin-like receptors.	Mannose	202-209	galactose mutarotase	Mus musculus	173-177
23741304-8	2013	SPR-analysis also demonstrated that wild-type GRFT and its single mutant CBS variants have the capacity to expel bound gp120 from the gp120-DC-SIGN complex in a dose dependent manner, a property that was not observed for HHA, another mannose-specific potent anti-HIV-1 CBA.	Mannose	234-241	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	119-124
23422590-0	2013	Delivery of a granzyme B inhibitor gene using carbamate-mannose modified PEI protects against cytotoxic lymphocyte killing.	Mannose	56-63	granzyme B	Homo sapiens	14-24
23741476-1	2013	It has been suggested that genetic variants in mannose binding lectin (MBL2) influence susceptibility and outcome of invasive pneumococcal disease.	Mannose	47-54	mannose binding lectin 2	Homo sapiens	71-75
23734186-8	2013	Significant binding of Bla g 2 to CD206 was observed, which was inhibited by yeast mannan (a known CD206 ligand), free mannose, and a blocking antibody (anti-hMR).	Mannose	119-126	mannose receptor C-type 1	Homo sapiens	34-39
23734186-12	2013	This increased secretion of TNF-alpha and IL-6 and activation of NF-kB, ERK, and JNK was significantly inhibited by the addition of either mannan or mannose.	Mannose	149-156	tumor necrosis factor	Homo sapiens	28-37
23734186-12	2013	This increased secretion of TNF-alpha and IL-6 and activation of NF-kB, ERK, and JNK was significantly inhibited by the addition of either mannan or mannose.	Mannose	149-156	interleukin 6	Homo sapiens	42-46
23734186-12	2013	This increased secretion of TNF-alpha and IL-6 and activation of NF-kB, ERK, and JNK was significantly inhibited by the addition of either mannan or mannose.	Mannose	149-156	mitogen-activated protein kinase 1	Homo sapiens	72-75
23734186-12	2013	This increased secretion of TNF-alpha and IL-6 and activation of NF-kB, ERK, and JNK was significantly inhibited by the addition of either mannan or mannose.	Mannose	149-156	mitogen-activated protein kinase 8	Homo sapiens	81-84
23422590-11	2013	Therefore, these carbamate-mannose modified PEI/PI-9 encoding plasmid complexes have potential clinical utility in the prevention of chronic transplant rejection and inflammatory disease caused by GrB.	Mannose	27-34	serpin family B member 9	Homo sapiens	48-52
23422590-11	2013	Therefore, these carbamate-mannose modified PEI/PI-9 encoding plasmid complexes have potential clinical utility in the prevention of chronic transplant rejection and inflammatory disease caused by GrB.	Mannose	27-34	granzyme B	Homo sapiens	197-200
23456435-4	2013	In mammalian heart, CSQ2 molecules subsequently undergo extensive mannose trimming by ER mannosidase(s), a posttranslational process that often regulates protein breakdown.	Mannose	66-73	calsequestrin 2	Canis lupus familiaris	20-24
23456435-9	2013	Unique to all samples analyzed from HF dog hearts, 20-40 % of all CSQ2 contained glycans that had minimal mannose trimming (Man9,8).	Mannose	106-113	calsequestrin 2	Canis lupus familiaris	66-70
23500721-1	2013	Pinellia ternata agglutinin (PTA) from the tubers of P. ternata is a two-domain monocot mannose-binding lectin.	Mannose	88-95	pre T cell antigen receptor alpha	Homo sapiens	29-32
23462048-10	2013	Endo H-mediated deglycosylation of GluR2 resulted in a significantly smaller pool of GluR2 protein to shift in schizophrenia, reflecting less N-linked high mannose and/or hybrid sugars on the GluR2 protein in this illness.	Mannose	156-163	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	35-40
23462048-10	2013	Endo H-mediated deglycosylation of GluR2 resulted in a significantly smaller pool of GluR2 protein to shift in schizophrenia, reflecting less N-linked high mannose and/or hybrid sugars on the GluR2 protein in this illness.	Mannose	156-163	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	85-90
23462048-10	2013	Endo H-mediated deglycosylation of GluR2 resulted in a significantly smaller pool of GluR2 protein to shift in schizophrenia, reflecting less N-linked high mannose and/or hybrid sugars on the GluR2 protein in this illness.	Mannose	156-163	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	85-90
23462048-11	2013	This was confirmed by immunoisolation of GluR2 and probing with Concanavalin A, a mannose specific lectin; in subjects with schizophrenia GluR2 was significantly less reactive to Concanavalin A. Altered N-linked glycosylation of the GluR2 subunit in schizophrenia suggests abnormal trafficking of AMPA receptors from the ER to the synaptic membrane in schizophrenia.	Mannose	82-89	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	138-143
23462048-11	2013	This was confirmed by immunoisolation of GluR2 and probing with Concanavalin A, a mannose specific lectin; in subjects with schizophrenia GluR2 was significantly less reactive to Concanavalin A. Altered N-linked glycosylation of the GluR2 subunit in schizophrenia suggests abnormal trafficking of AMPA receptors from the ER to the synaptic membrane in schizophrenia.	Mannose	82-89	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	138-143
23319563-5	2013	Using a mouse model of NCC by infection with the related parasite Mesocestoides corti, we have investigated the role of mannose receptor C type 1 (MRC1), a CLR which recognizes high-mannose-containing glycan antigens.	Mannose	120-127	mannose receptor, C type 1	Mus musculus	147-151
23417900-0	2013	Selective targeting of dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) with mannose-based glycomimetics: synthesis and interaction studies of bis(benzylamide) derivatives of a pseudomannobioside.	Mannose	117-124	CD209 molecule	Homo sapiens	23-101
23417900-0	2013	Selective targeting of dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) with mannose-based glycomimetics: synthesis and interaction studies of bis(benzylamide) derivatives of a pseudomannobioside.	Mannose	117-124	CD209 molecule	Homo sapiens	103-110
23417900-1	2013	Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) and Langerin are C-type lectins of dendritic cells (DCs) that share a specificity for mannose and are involved in pathogen recognition.	Mannose	175-182	CD209 molecule	Homo sapiens	0-78
23417900-1	2013	Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) and Langerin are C-type lectins of dendritic cells (DCs) that share a specificity for mannose and are involved in pathogen recognition.	Mannose	175-182	CD209 molecule	Homo sapiens	80-87
23417900-1	2013	Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) and Langerin are C-type lectins of dendritic cells (DCs) that share a specificity for mannose and are involved in pathogen recognition.	Mannose	175-182	CD207 molecule	Homo sapiens	93-101
23417900-5	2013	We show here for the first time that glycomimetics based on a mannose anchor can be tuned to selectively inhibit DC-SIGN over Langerin.	Mannose	62-69	CD209 molecule	Homo sapiens	113-120
23417900-5	2013	We show here for the first time that glycomimetics based on a mannose anchor can be tuned to selectively inhibit DC-SIGN over Langerin.	Mannose	62-69	CD207 molecule	Homo sapiens	126-134
23347838-2	2013	Mannose-modified trimethyl chitosan-cysteine (MTC) conjugate nanoparticles (NPs) were developed via ionic gelation and performed as highly effective polymeric vehicles for oral delivery of TNF-alpha siRNA.	Mannose	0-7	tumor necrosis factor	Mus musculus	189-198
23592124-1	2013	Numerous studies have been done to explore the association between mannose-binding lectin two (MBL2) gene polymorphisms and the risk of tuberculosis (TB).	Mannose	67-74	mannose binding lectin 2	Homo sapiens	95-99
23599794-0	2013	Pseudomonas aeruginosa-mannose-sensitive hemagglutinin inhibits proliferation and induces apoptosis in a caspase-dependent manner in human bladder cancer cell lines.	Mannose	23-30	caspase 8	Homo sapiens	105-112
23339644-7	2013	For N-linked glycosylation, two sites (N386 and N392) in the V4 region were populated with high mannose glycans in the CHO cell-derived 1086.C gp120, while these sites had a mixture of high mannose and processed glycans in the 293T cell-derived 1086.C gp120.	Mannose	96-103	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	143-148
23220107-14	2013	Nanogel-delivered ova with mannose surface decoration was superior to free ova for inducing interferon-gamma production by T-lymphocytes.	Mannose	27-34	interferon gamma	Homo sapiens	92-108
23023834-3	2013	Both families recognize different epitopes on high-mannose glycans, namely, Manalpha(1-2)Man units at the end of the D1 and D3 arms and alpha3,alpha6-mannopentaose at the central branch point of Man-8 or Man-9 for CVNH and OAAH lectins, respectively.	Mannose	51-58	mannosidase alpha class 1A member 1	Homo sapiens	204-209
23042514-4	2013	The PLS2 model is able to predict concentrations of both major sugar components, like glucose and xylose, and minor sugars, such as arabinose and mannose, in biomass hydrolysates.	Mannose	146-153	lymphocyte cytosolic protein 1	Homo sapiens	4-8
23339644-7	2013	For N-linked glycosylation, two sites (N386 and N392) in the V4 region were populated with high mannose glycans in the CHO cell-derived 1086.C gp120, while these sites had a mixture of high mannose and processed glycans in the 293T cell-derived 1086.C gp120.	Mannose	96-103	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	252-257
23464634-7	2013	The present data show that mannose, a recently described inhibitor of hyaluronan synthesis, inhibits dermal fibroblast invasion and prevents the enhanced leukocyte binding to hyaluronan that takes place in cells treated with an inflammatory mediator interleukin-1beta.	Mannose	27-34	interleukin 1 beta	Homo sapiens	250-267
23439277-0	2013	Mannose binding lectin (mbl2) haplotype frequencies in solid organ transplant patients and correlation with MBL protein levels--evaluation of complement-mediated effector pathway deficiency.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-28
23221565-1	2013	The highly conserved cluster of high-mannose glycans on the HIV-1 envelope glycoprotein, gp120, has been highlighted as a target for neutralizing antibodies.	Mannose	37-44	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	89-94
23281814-0	2013	Structural and biochemical characterization of the N-terminal domain of flocculin Lg-Flo1p from Saccharomyces pastorianus reveals a unique specificity for phosphorylated mannose.	Mannose	170-177	flocculin FLO1	Saccharomyces cerevisiae S288C	85-90
23247087-4	2013	To extend the knowledge about flocculation to the protein level, we isolated the N-terminal domain of the Flo1p (N-Flo1p) that contains the mannose-binding domain, which is responsible for the strong interaction (flocculation) of S. cerevisiae cells.	Mannose	140-147	flocculin FLO1	Saccharomyces cerevisiae S288C	106-111
23247087-4	2013	To extend the knowledge about flocculation to the protein level, we isolated the N-terminal domain of the Flo1p (N-Flo1p) that contains the mannose-binding domain, which is responsible for the strong interaction (flocculation) of S. cerevisiae cells.	Mannose	140-147	flocculin FLO1	Saccharomyces cerevisiae S288C	115-120
23205949-4	2013	Deprotection of the acetate protecting groups from the hyperbranched mannose polymers yields water-soluble polymers that interact with mannose binding lectin (MBL), a key protein of the innate immunity complement system.	Mannose	69-76	mannose binding lectin 2	Homo sapiens	135-157
23205949-4	2013	Deprotection of the acetate protecting groups from the hyperbranched mannose polymers yields water-soluble polymers that interact with mannose binding lectin (MBL), a key protein of the innate immunity complement system.	Mannose	69-76	mannose binding lectin 2	Homo sapiens	159-162
23205949-6	2013	Notably, incorporating mannose into the branching repeat unit also increases the interaction of the glycopolymers with MBL compared with glycopolymers with the same branching density but with no mannose at the branch point.	Mannose	23-30	mannose binding lectin 2	Homo sapiens	119-122
22900599-9	2013	CONCLUSIONS: Strain K20 produced EPSs, mainly consisting of mannose, and formed biofilms.	Mannose	60-67	keratin 20	Mus musculus	20-23
23689575-6	2013	These autoantibodies bind to genetically determined, conformational epitopes on PLA2R1, form immune complexes in situ and induce proteinuria, mostly likely via local activation of complement via the mannose-binding lectin pathway.	Mannose	199-206	phospholipase A2 receptor 1	Homo sapiens	80-86
23005037-3	2013	In the present study, mass spectrum analysis demonstrated that the purified native CD147 from human lung cancer tissue was N-glycosylated and contained a series of high-mannose and complex-type N-linked glycan structures.	Mannose	169-176	basigin (Ok blood group)	Homo sapiens	83-88
22820482-7	2013	Furthermore, ligands targeting immune cells (i.e. mannose) or the inflamed colon (i.e. a specific peptide) were grafted on the PEG chain of PCL.	Mannose	50-57	polycystic kidney disease 2-like 1	Mus musculus	140-143
23848537-2	2013	Using this method, a series of 3-deoxycarbasugar analogues of mannose bearing a pyridyl group are rationally designed, prepared and tested for inhibition of Golgi alpha-mannosidase II.	Mannose	62-69	mannosidase alpha class 2A member 1	Homo sapiens	157-183
22899857-5	2013	MPI-CDG patients can be treated with oral mannose supplements, which is converted to mannose-6-phosphate through a minor complementary metabolic pathway, restoring protein glycosylation and ameliorating most symptoms, although liver disease continues to progress.	Mannose	42-49	mannose phosphate isomerase	Homo sapiens	0-3
24367138-9	2013	Characteristic PCa PSA-IgM glycoforms pose the question of the possible role of glycosylation as a framework for immune surveillance and may be of interest in light of recent data indicating mannose-containing glycans as cancer biomarker.	Mannose	191-198	kallikrein related peptidase 3	Homo sapiens	19-22
24047736-2	2013	To explore the role of mannose-binding lectin (MBL), a pattern recognition molecule of the innate immune system, in intrauterine transmission of HBV, we determined MBL levels using an enzyme-linked immunosorbent assay (ELISA) in cord serum of 7 intrauterine-infected neonates and 30 non-infected neonates born to HBV-positive mothers, and 30 control neonates born to HBV-negative mothers.	Mannose	23-30	mannose binding lectin 2	Homo sapiens	47-50
23012214-4	2013	A complex glycoprofile is observed for NLF, including sialic acid, fucose, mannose, and Lewis (Le)(x)  structures, whereas both rLF species display a simpler glycoprofile rich in mannose.	Mannose	179-186	RLF zinc finger	Rattus norvegicus	128-131
23573288-1	2013	Mannose-binding lectin (MBL) is a key soluble effector of the innate immune system that recognizes pathogen-specific surface glycans.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
23129756-0	2012	Mannose-capped lipoarabinomannan from Mycobacterium tuberculosis preferentially inhibits sphingosine-1-phosphate-induced migration of Th1 cells.	Mannose	0-7	negative elongation factor complex member C/D, Th1l	Mus musculus	134-137
23527085-5	2013	The binding of SP-D to HIV particles and gp120 was inhibited by the presence of several hexoses with mannose found to be the strongest inhibitor.	Mannose	101-108	surfactant protein D	Homo sapiens	15-19
23527085-5	2013	The binding of SP-D to HIV particles and gp120 was inhibited by the presence of several hexoses with mannose found to be the strongest inhibitor.	Mannose	101-108	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	41-46
22476631-1	2012	The bisecting GlcNAc is transferred to the core mannose residue of complex or hybrid N-glycans on glycoproteins by the beta1,4-N-acetylglucosaminyltransferase III (GlcNAcT-III) or MGAT3.	Mannose	48-55	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Cricetulus griseus	180-185
22982058-3	2012	In this study, the binding of glycoproteins with specific high-mannose or human N- and O-linked glycan structures to DC-SIGN was tested.	Mannose	63-70	CD209 molecule	Homo sapiens	117-124
22982058-4	2012	Proteins with humanized N-glycans including Man5 structures and O-glycans (up to as many as 24) with single mannose chain length showed DC-SIGN binding that was comparable to that measured for a CHO-produced IgG1 which lacks O-linked mannose.	Mannose	108-115	CD209 molecule	Homo sapiens	136-143
23151632-2	2012	In order to clarify the structural evidence for its specific binding to the alpha(1-2)mannobiose (MB) moiety of the D1 chains of high-mannose-type glycans (HMTGs) attached to HIV-1 gp120, the crystal structure of AH in complex with MB has been determined.	Mannose	134-141	adrenoceptor alpha 1D	Homo sapiens	76-85
23225056-1	2012	OBJECTIVE: To assess the association between single nucleotide polymorphisms (SNPs) of mannose-binding lectin 2 gene (MBL2) (rs1800450, rs1800451 and rs11003125) and protein kinase C-beta 1 gene (PRKC beta 1) (rs3700106, rs2575390) with diabetic macroangiopathy in northern Chinese Han population.	Mannose	87-94	mannose binding lectin 2	Homo sapiens	118-122
23100517-7	2012	Receptor-blocking and cross-linking studies showed that these inhibitory effects of gp120 were mediated by interactions with CD4 and mannose-binding C-type lectin receptors, but not with the chemokine receptors CCR5 and CXCR4.	Mannose	133-140	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	84-89
22607556-2	2012	We wanted to evaluate whether two mannose-specific CBAs, recognizing multiple and often distinct glycan structures on the HIV envelope gp120, can interact synergistically against HIV-1, HIV-2, and HIV-1 strains that were selected for resistance against particular CBAs [i.e., 2G12 mAb and microvirin (MVN)].	Mannose	34-41	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	135-140
22813905-4	2012	These forms of lactoferrin have identical amino acid sequences, but different glycosylation patterns: hmNLF and nNLF have complex glycoprofiles including Lewis (Le)(x) structures, with particularly high levels of Le(x) expressed by nNLF, whereas RLF is simpler and rich in mannose residues.	Mannose	273-280	lactotransferrin	Mus musculus	15-26
22988249-5	2012	The predominance of high mannose N-glycans in ES cells shifted to an equal abundance of complex and high mannose structures, increased sialylation, and increased alpha-Gal termination in the differentiated cell populations.	Mannose	25-32	glycoprotein galactosyltransferase alpha 1, 3	Mus musculus	162-171
22920536-0	2012	Cation clock permits distinction between the mechanisms of alpha- and beta-O- and beta-C-glycosylation in the mannopyranose series: evidence for the existence of a mannopyranosyl oxocarbenium ion.	Mannose	110-123	colony stimulating factor 2 receptor subunit beta	Homo sapiens	59-88
22871093-1	2012	Mannose-binding lectins, such as dendritic cell-specific ICAM-3-grabbing non-integrin (DC-SIGN), are expressed at the surface of human dendritic cells (DCs) that capture and transmit human immunodeficiency virus type-1 (HIV-1) to CD4(+) cells.	Mannose	0-7	CD209 molecule	Homo sapiens	33-85
22871093-1	2012	Mannose-binding lectins, such as dendritic cell-specific ICAM-3-grabbing non-integrin (DC-SIGN), are expressed at the surface of human dendritic cells (DCs) that capture and transmit human immunodeficiency virus type-1 (HIV-1) to CD4(+) cells.	Mannose	0-7	CD209 molecule	Homo sapiens	87-94
22728640-4	2012	IBP consisted of mannose, glucuronic acid, rhamnose, galacturonic acid, glucose, galactose, arabinose with a molar ratio of 4.1:1:1.4:2.7:14.6:6.3:7.9.	Mannose	17-24	trafficking protein particle complex 9	Mus musculus	0-3
22970832-4	2012	In a proof of principle and motivated by the importance of glycan-modified materials, many alkynyl-terminated mannose units were grated onto graphene/TTF-N(3).	Mannose	110-117	ras homolog family member H	Homo sapiens	150-153
22970832-5	2012	The TTF-mannose units could be released efficiently from the graphene matrix by chemical oxidation of TTF-mannose surface units to TTF(2+)-mannose, using Fe(ClO(4))(3) or the electron-deficient tetracationic cyclophane cyclobis(paraquat-p-phenylene) (CBPQT(4+)).	Mannose	8-15	ras homolog family member H	Homo sapiens	4-7
22970832-5	2012	The TTF-mannose units could be released efficiently from the graphene matrix by chemical oxidation of TTF-mannose surface units to TTF(2+)-mannose, using Fe(ClO(4))(3) or the electron-deficient tetracationic cyclophane cyclobis(paraquat-p-phenylene) (CBPQT(4+)).	Mannose	8-15	ras homolog family member H	Homo sapiens	102-105
22970832-5	2012	The TTF-mannose units could be released efficiently from the graphene matrix by chemical oxidation of TTF-mannose surface units to TTF(2+)-mannose, using Fe(ClO(4))(3) or the electron-deficient tetracationic cyclophane cyclobis(paraquat-p-phenylene) (CBPQT(4+)).	Mannose	8-15	ras homolog family member H	Homo sapiens	102-105
23060289-3	2012	We identified beta(1,4)-N-acetylglucosamine oligomers (GlcNAc) and GlcNAc/branched mannose in BSA, IgG, TNF-alpha, and THP, but not in IFN-g.	Mannose	83-90	uromodulin	Homo sapiens	119-122
23060289-5	2012	Small amounts of Siaalpha(2,3)Gal/ GalNAc, Sia(2,6)Gal/GalNAc, and mannose residues were also present in THP and TNF-alpha.	Mannose	67-74	uromodulin	Homo sapiens	105-108
23060289-5	2012	Small amounts of Siaalpha(2,3)Gal/ GalNAc, Sia(2,6)Gal/GalNAc, and mannose residues were also present in THP and TNF-alpha.	Mannose	67-74	tumor necrosis factor	Homo sapiens	113-122
22985026-2	2012	Present study elucidates the role of phenolicglycolipid (PGL-1) and Mannose-capped lipoarabinomannan (Man-LAM) on TCR- and TCR/CD28- mediated signalling.	Mannose	68-75	CD28 molecule	Homo sapiens	127-131
22495737-2	2012	Mannanases (beta-mannanases) hydrolyse beta-(1-4)-linked mannose residues randomly in mannans whilst cellulases (beta-glucanase) hydrolyse beta-(1-4)-linked glucose residues.	Mannose	57-64	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	39-48
22475410-5	2012	Specificity analyses of the CRDs reveal some differences in their preferences for saccharides: CL-11 binds most avidly to l-fucose and d-mannose, whereas CL-L1 shows preference for d-mannose, d-fucose, N-acetylglucosamine, and surprisingly also d-galactose.	Mannose	135-144	collectin subfamily member 11	Homo sapiens	95-100
22475410-5	2012	Specificity analyses of the CRDs reveal some differences in their preferences for saccharides: CL-11 binds most avidly to l-fucose and d-mannose, whereas CL-L1 shows preference for d-mannose, d-fucose, N-acetylglucosamine, and surprisingly also d-galactose.	Mannose	181-190	collectin subfamily member 10	Homo sapiens	154-159
23163040-9	2012	Per oral administration of mannose and probiotic strains together with mannose was established to cause stimulating effect on functional activity of macrophages increasing ingesting and digesting ability of the cells and facilitates reduction of TNF-alpha levels.	Mannose	27-34	tumor necrosis factor	Mus musculus	246-255
23163040-9	2012	Per oral administration of mannose and probiotic strains together with mannose was established to cause stimulating effect on functional activity of macrophages increasing ingesting and digesting ability of the cells and facilitates reduction of TNF-alpha levels.	Mannose	71-78	tumor necrosis factor	Mus musculus	246-255
22495737-2	2012	Mannanases (beta-mannanases) hydrolyse beta-(1-4)-linked mannose residues randomly in mannans whilst cellulases (beta-glucanase) hydrolyse beta-(1-4)-linked glucose residues.	Mannose	57-64	tubulin beta 3 class III	Homo sapiens	139-148
22824309-2	2012	Major goat sperm maturation antigen (SMA2) contains one hexosamine along with mannose, galactose and glucose.	Mannose	78-85	survival of motor neuron 1, telomeric	Homo sapiens	37-41
22895706-6	2012	Increasing TMEM106B expression to model disease results in enlargement and poor acidification of endo-lysosomes, as well as impairment of mannose-6-phosphate-receptor trafficking.	Mannose	138-145	transmembrane protein 106B	Homo sapiens	11-19
22700724-6	2012	Binding was reduced significantly in the absence of Ca(2+) and by preincubation of DC-SIGN with mannan, suggesting that C1q binds to DC-SIGN at its principal Ca(2+)-binding pocket, which has increased affinity for mannose residues.	Mannose	214-221	complement C1q A chain	Homo sapiens	120-123
22723438-3	2012	We recently showed that tumor necrosis factor-alpha increased hypoglycosylated (mannose-rich) N-glycans on the endothelial surface.	Mannose	80-87	tumor necrosis factor	Homo sapiens	24-51
22779691-2	2012	This study investigates the anti-HCMV activities of mannose-binding lectin (MBL) from blocking virus entry and inhibiting virus spread.	Mannose	52-59	mannose binding lectin 2	Homo sapiens	76-79
22723438-5	2012	METHODS AND RESULTS: Staining with the mannose-specific lectins concanavalin A and lens culinaris agglutinin was increased in human aortic endothelial cells exposed to oscillatory shear or tumor necrosis factor-alpha and at sites of plaque development and progression in both mice and human vessels.	Mannose	39-46	tumor necrosis factor	Homo sapiens	189-216
22271390-0	2012	Efficient suppression of murine intracellular adhesion molecule-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation.	Mannose	98-105	intercellular adhesion molecule 1	Homo sapiens	32-65
22571197-7	2012	Moreover, we clearly show that not only the complex type, but also a high-mannose type, of TbetaRII can be localized on the cell surface.	Mannose	74-81	transforming growth factor beta receptor 2	Homo sapiens	91-99
22296677-2	2012	Previous reports have indicated that carriage of common "defective" structural polymorphisms of the host mannose-binding lectin gene (MBL2) greatly increases an individual"s risk of developing the disease.	Mannose	105-112	mannose binding lectin 2	Homo sapiens	134-138
22762710-3	2012	We investigated mannose binding (MBL) during cold ischemia and in tissue samples from explanted lungs with BOS, and assessed MBL and complement proteins in plasma post-lung transplantation relative to BOS staging.	Mannose	16-23	mannose binding lectin 2	Homo sapiens	33-36
22695166-3	2012	Mass spectrum (quadrupole time of flight [Q-TOF]) analyses of multimeric scFv demonstrated extensive heterogeneity due to differential cleavage, variable glycosylation (1 to 9 mannose residues), and the incorporation of minor unidentified adducts.	Mannose	176-183	immunglobulin heavy chain variable region	Homo sapiens	73-77
22466447-4	2012	The study on the function of FLO10 (spsc) by its integrative expression in the non-flocculating industrial yeast indicated severe inhibition in the flocculation of the transformant by mannose and maltose, moderate inhibition by sucrose and glucose and no inhibition by xylose and galactose, and thus the NewFlo type was established.	Mannose	184-191	Flo10p	Saccharomyces cerevisiae S288C	29-34
22733738-4	2012	EBS3 encodes the Arabidopsis ortholog of the yeast asparagine-linked glycosylation 9 (ALG9), which catalyzes the ER luminal addition of two terminal alpha1,2 mannose (Man) residues in assembling the three-branched N-glycan precursor [glucose(Glc)](3)(Man)(9)[N-acetylglucosamine(GlcNAc)](2).	Mannose	158-165	Alg9-like mannosyltransferase family	Arabidopsis thaliana	0-4
22733738-4	2012	EBS3 encodes the Arabidopsis ortholog of the yeast asparagine-linked glycosylation 9 (ALG9), which catalyzes the ER luminal addition of two terminal alpha1,2 mannose (Man) residues in assembling the three-branched N-glycan precursor [glucose(Glc)](3)(Man)(9)[N-acetylglucosamine(GlcNAc)](2).	Mannose	158-165	dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase	Saccharomyces cerevisiae S288C	51-84
22733738-4	2012	EBS3 encodes the Arabidopsis ortholog of the yeast asparagine-linked glycosylation 9 (ALG9), which catalyzes the ER luminal addition of two terminal alpha1,2 mannose (Man) residues in assembling the three-branched N-glycan precursor [glucose(Glc)](3)(Man)(9)[N-acetylglucosamine(GlcNAc)](2).	Mannose	158-165	dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase	Saccharomyces cerevisiae S288C	86-90
22271390-4	2012	Here, we developed an ICAM-1 small interfering RNA (siRNA) transfer method using ultrasound (US)-responsive and mannose-modified liposome/ICAM-1 siRNA complexes (Man-PEG(2000) bubble lipoplexes [Man-PEG(2000) BLs]), and achieved efficient HEC-selective ICAM-1 siRNA delivery in combination with US exposure.	Mannose	112-119	intercellular adhesion molecule 1	Homo sapiens	22-28
22271390-4	2012	Here, we developed an ICAM-1 small interfering RNA (siRNA) transfer method using ultrasound (US)-responsive and mannose-modified liposome/ICAM-1 siRNA complexes (Man-PEG(2000) bubble lipoplexes [Man-PEG(2000) BLs]), and achieved efficient HEC-selective ICAM-1 siRNA delivery in combination with US exposure.	Mannose	112-119	intercellular adhesion molecule 1	Homo sapiens	138-144
22271390-4	2012	Here, we developed an ICAM-1 small interfering RNA (siRNA) transfer method using ultrasound (US)-responsive and mannose-modified liposome/ICAM-1 siRNA complexes (Man-PEG(2000) bubble lipoplexes [Man-PEG(2000) BLs]), and achieved efficient HEC-selective ICAM-1 siRNA delivery in combination with US exposure.	Mannose	112-119	intercellular adhesion molecule 1	Homo sapiens	138-144
22628288-3	2012	Among these, the monoclonal antibody 2G12 binds to clusters of high-mannose-type glycans that are present on the surface of gp120.	Mannose	68-75	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	124-129
22417285-3	2012	AtERF98-overexpressing plants showed enhanced expression of AsA synthesis genes in the d-mannose/l-galactose (d-Man/l-Gal) pathway and the myo-inositol pathway gene MIOX4, as well as of AsA turnover genes.	Mannose	87-96	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	0-7
22550939-7	2012	Mannose functionalization of these nanohybrids showed specificity for both murine and human macrophage-like cell lines RAW 264.7 and human acute monocytic leukemia cell line (THP1), respectively, with a significant level (P &lt; 0.05) of expression of gaussia luciferase (GLuc) and green fluorescent reporter plasmids.	Mannose	0-7	GLI family zinc finger 2	Homo sapiens	175-179
21823122-10	2012	In addition, increased mannose expression was observed and branched N-glycans were prominent, and this correlated well with human Galectin-3 binding.	Mannose	23-30	galectin 3	Homo sapiens	130-140
22584580-6	2012	The starch-degrading activity of PPA and maltose-degrading activity of SI were enhanced to 240 and 175%, respectively, while Glc uptake by SGLT1 was markedly inhibited by PPA at high but physiologically possible concentrations, and the binding was attenuated by the addition of mannose-specific lectins, especially from Galanthus nivalis.	Mannose	278-285	solute carrier family 5 member 1	Homo sapiens	139-144
22562613-4	2012	The permeability of mannosylated LZ liposomes across Caco-2 cell monolayers was significantly enhanced to about 2.5- and 7-folds over those of conventional liposomes and solution, respectively, which might be due to the role of mannose receptor or mannose-binding protein on the intestinal enterocytes.	Mannose	228-235	lysozyme	Homo sapiens	33-35
22290613-2	2012	This study examined efficacy of the innate immune defence via the mannose binding lectin (MBL) in a cohort of 55 dystonic patients prospectively referred to the clinic with laryngeal mucosal complaints, who were placed on local steroids (budesonid inhaler, 400 mug 2 times daily) and antihistamines (fexofenadin 180 mg mostly 3 times daily) with adjuvant lifestyle corrections.	Mannose	66-73	mannose binding lectin 2	Homo sapiens	90-93
22547820-2	2012	Concordant with recent evidence that HIV-1 titers are determined by a race between entry of cell-attached virions and competing inactivation processes, we show that NMAb 2G12, which binds to gp120 N-glycans with alpha (1, 2)-linked mannose termini and inhibits replication after passive transfer into patients, neutralizes by slowing entry of adsorbed virions.	Mannose	232-239	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	191-196
22225939-1	2012	Several studies suggest mannose-binding lectin (MBL) deficiency is associated with various manifestations of aspergillosis.	Mannose	24-31	mannose binding lectin 2	Homo sapiens	48-51
22496445-6	2012	Mannose supplementation of phosphomannose isomerase-deficient CDG-Ib (MPI-CDG) cells and complementation with PMM2 in PMM2-deficient CDG-Ia (PMM2-CDG) cells partially corrected hypoglycosylation based on increased ICAM-1 presence on the plasma membrane.	Mannose	0-7	intercellular adhesion molecule 1	Homo sapiens	214-220
22442036-5	2012	Surprisingly, the majority of the N-glycans of Col-IDUA-SEKDEL were complex N-glycans (i.e. contained xylose and/or fucose) (88 %), whereas complex N-glycans comprised a much lower proportion of the N-glycans of cgl-IDUA-SEKDEL (26 %), in which high-mannose forms were predominant.	Mannose	250-257	alpha-L-iduronidase	Homo sapiens	51-55
22852409-3	2012	The water-soluble hyperbranched polymer (HP) exhibited enhanced fluorescence intensity upon exposure to lectin in the presence of mannose compared to other proteins, such as lysozyme and cytochrome c, because mannose plays a key role in binding both lectin and HP resulting in selective sensing toward lectin.	Mannose	209-216	cytochrome c, somatic	Homo sapiens	187-199
22505413-3	2012	Human p19 and p40 subunits were cloned and coexpressed in N-acetylglucosaminyltransferase I-negative 293S cells, which produce high-mannose-type glycosylated proteins in order to diminish the heterogeneity of modified N-linked glycans.	Mannose	132-139	interleukin 23 subunit alpha	Homo sapiens	6-9
22422887-8	2012	This novel pathway is specific to C1q because mannose-binding lectin, a related collectin, failed to upregulate Mer expression and function.	Mannose	46-53	complement component 1, q subcomponent, alpha polypeptide	Mus musculus	34-37
22505413-3	2012	Human p19 and p40 subunits were cloned and coexpressed in N-acetylglucosaminyltransferase I-negative 293S cells, which produce high-mannose-type glycosylated proteins in order to diminish the heterogeneity of modified N-linked glycans.	Mannose	132-139	interleukin 9	Homo sapiens	14-17
22262853-4	2012	A complete understanding of the physiological relevance of latent TGF-beta1 mannose phosphorylation, however, is still lacking.	Mannose	76-83	transforming growth factor beta 1	Homo sapiens	66-75
22391090-3	2012	PEP contained Mannose, Glucose, and Galactose in a ratio of 4.8:50.9:44.3.	Mannose	14-21	progestagen associated endometrial protein	Homo sapiens	0-3
22382028-5	2012	In the mnn2 mutant, the gene coding the activity of attaching first branching mannose residue to mannan main chain is deleted and therefore the mnn2 mutant has unbranched mannan.	Mannose	78-85	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	7-11
22382028-5	2012	In the mnn2 mutant, the gene coding the activity of attaching first branching mannose residue to mannan main chain is deleted and therefore the mnn2 mutant has unbranched mannan.	Mannose	78-85	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	144-148
22156919-3	2012	Here, we used a series of alpha-galactomannans (GMs) that vary in their mannose-to-galactose ratios for insight into an optimal structural signature for GM binding to gal-1.	Mannose	72-79	galectin 1	Homo sapiens	167-172
22156919-4	2012	Heteronuclear single-quantum coherence nuclear magnetic resonance spectroscopy with (15)N-labeled gal-1 and statistical modeling suggest that the optimal signature consists of alpha-D-galactopyranosyl doublets surrounded by regions of about four or more "naked" mannose residues.	Mannose	262-269	galectin 1	Homo sapiens	98-103
22155215-8	2012	TGA results indicated that mannose grafted to chitosan slightly decreased the thermal stability of chitosan in some extent.	Mannose	27-34	T-box transcription factor 1	Homo sapiens	0-3
22326920-6	2012	Notably, they also used Saccharomyces cerevisiaeO-mannans as acceptors and generated products with more than three mannose residues, suggesting than Mnt1 and Mnt2 could be the mannosyltransferases adding the fourth and fifth mannose residue to the O-mannans in C. albicans.	Mannose	115-122	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	149-153
22326920-6	2012	Notably, they also used Saccharomyces cerevisiaeO-mannans as acceptors and generated products with more than three mannose residues, suggesting than Mnt1 and Mnt2 could be the mannosyltransferases adding the fourth and fifth mannose residue to the O-mannans in C. albicans.	Mannose	115-122	alpha-1,3-mannosyltransferase MNT2	Saccharomyces cerevisiae S288C	158-162
22326920-6	2012	Notably, they also used Saccharomyces cerevisiaeO-mannans as acceptors and generated products with more than three mannose residues, suggesting than Mnt1 and Mnt2 could be the mannosyltransferases adding the fourth and fifth mannose residue to the O-mannans in C. albicans.	Mannose	225-232	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	149-153
22262853-5	2012	Here we investigate the degree of mannose phosphorylation on secreted latent TGF-beta1 and examine its Man-6-P-dependent activation in primary human corneal stromal fibroblasts.	Mannose	34-41	transforming growth factor beta 1	Homo sapiens	77-86
22326920-6	2012	Notably, they also used Saccharomyces cerevisiaeO-mannans as acceptors and generated products with more than three mannose residues, suggesting than Mnt1 and Mnt2 could be the mannosyltransferases adding the fourth and fifth mannose residue to the O-mannans in C. albicans.	Mannose	225-232	alpha-1,3-mannosyltransferase MNT2	Saccharomyces cerevisiae S288C	158-162
22262853-8	2012	Moreover, the efficient processing of glycans on latent TGF-beta1 to complex type structures was consistent with the lack of mannose phosphorylation during biosynthesis.	Mannose	125-132	transforming growth factor beta 1	Homo sapiens	56-65
22380611-4	2012	In particular, the main African mannose-binding lectin deficiency variant (MBL2*G57E, rs1800451) increased the odds of placental malaria (OR 1.6; permuted p-value 0.014).	Mannose	32-39	mannose binding lectin 2	Homo sapiens	75-79
21793733-0	2012	Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice.	Mannose	14-21	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	70-75
22228761-7	2012	The GPI-anchored protein was secreted substantially into medium from PIGV-, PIGB-, and PIGF-deficient CHO cells, in which incomplete GPI bearing mannose was accumulated.	Mannose	145-152	phosphatidylinositol-glycan biosynthesis class F protein	Cricetulus griseus	87-91
22228761-8	2012	In contrast, ALP was degraded in PIGL-, DPM2-, or PIGX-deficient CHO cells, in which incomplete shorter GPIs that lacked mannose were accumulated.	Mannose	121-128	alkaline phosphatase, placental	Homo sapiens	13-16
22228761-9	2012	Our results suggest that GPI transamidase recognizes incomplete GPI bearing mannose and cleaves a hydrophobic signal peptide, resulting in secretion of soluble ALP.	Mannose	76-83	alkaline phosphatase, placental	Homo sapiens	160-163
22209231-2	2012	The lectins griffithsin (GRFT), cyanovirin-N (CV-N) and scytovirin (SVN) inhibit HIV-1 infection by binding to mannose-rich glycans on gp120.	Mannose	111-118	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	135-140
22408387-9	2012	The multiple spots detected for cerebrospinal fluid transferrin were mainly due to heterogeneity of di-antennary and tri-antennary glycans harboring a varying number of terminal N-acetylneuraminic acids and the existence of a high mannose and high N-acetylhexosamine glycosylated species.	Mannose	231-238	transferrin	Homo sapiens	52-63
22212718-5	2012	SGLT-5 mediates sodium-dependent [(14)C]-alpha-methyl-D-glucose (AMG) transport that can be inhibited by mannose, fructose, glucose, and galactose.	Mannose	105-112	solute carrier family 5 member 10	Homo sapiens	0-6
22212718-5	2012	SGLT-5 mediates sodium-dependent [(14)C]-alpha-methyl-D-glucose (AMG) transport that can be inhibited by mannose, fructose, glucose, and galactose.	Mannose	105-112	amelogenin X-linked	Homo sapiens	65-68
22212718-7	2012	SGLT-5 mediated mannose, fructose and AMG transport was weakly (muM potency) inhibited by SGLT-2 inhibitors.	Mannose	16-23	solute carrier family 5 member 10	Homo sapiens	0-6
22212718-7	2012	SGLT-5 mediated mannose, fructose and AMG transport was weakly (muM potency) inhibited by SGLT-2 inhibitors.	Mannose	16-23	solute carrier family 5 member 2	Homo sapiens	90-96
22191536-8	2012	It was found that FBP from human milk contains putative structures that have composition consistent with high-mannose (Hex(5-6)HexNAc(2)) as well as hybrid and complex N-linked glycans (NeuAc(0-1)Fuc(0-3)Hex(3-6)HexNAc(3-5)).	Mannose	110-117	folate receptor alpha	Homo sapiens	18-21
22191536-9	2012	The FBP from bovine milk contains putative structures corresponding to high-mannose (Hex(4-9)HexNAc(2)) as well as hybrid and complex N-linked glycans (Hex(3-6)HexNAc(3-6)), but these glycans mostly do not contain fucose and sialic acid.	Mannose	76-83	folate receptor alpha	Bos taurus	4-7
22227571-5	2012	2DG blocks N-linked glycosylation of MICA/B by a reversible mechanism that can be alleviated by addition of d-mannose; this does not, however, affect the inhibition of glycolysis.	Mannose	108-117	MHC class I polypeptide-related sequence A	Homo sapiens	37-41
22227571-6	2012	Addition of d-mannose restored MICA/B surface expression after 2DG treatment.	Mannose	12-21	MHC class I polypeptide-related sequence A	Homo sapiens	31-35
22227571-9	2012	NK cell-mediated killing assay and staining with a recombinant NKG2D-Fc fusion protein showed that all functional NKG2D ligands induced by histone deacetylase inhibitor treatment were abolished by 2DG treatment and fully reconstituted by further addition of d-mannose.	Mannose	258-267	killer cell lectin like receptor K1	Homo sapiens	63-68
22227571-9	2012	NK cell-mediated killing assay and staining with a recombinant NKG2D-Fc fusion protein showed that all functional NKG2D ligands induced by histone deacetylase inhibitor treatment were abolished by 2DG treatment and fully reconstituted by further addition of d-mannose.	Mannose	258-267	killer cell lectin like receptor K1	Homo sapiens	114-119
21793733-6	2012	We conclude that gp120-GRFT complexes are more immunogenic than the free proteins, for both components, and that occluding the mannose moieties on monomeric gp120 can improve the humoral immune response to this protein.	Mannose	127-134	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	17-22
21793733-6	2012	We conclude that gp120-GRFT complexes are more immunogenic than the free proteins, for both components, and that occluding the mannose moieties on monomeric gp120 can improve the humoral immune response to this protein.	Mannose	127-134	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	157-162
21893569-0	2012	Human ZG16p recognizes pathogenic fungi through non-self polyvalent mannose in the digestive system.	Mannose	68-75	zymogen granule protein 16	Homo sapiens	6-11
21948269-1	2012	This study was undertaken to detect polymorphisms in the goat and sheep mannose-binding lectin encoding gene (MBL2) and to explore allelic variability of this gene in these two species.	Mannose	72-79	mannose-binding lectin (protein C) 2, soluble (opsonic defect)	Ovis aries	110-114
22129043-0	2012	The N-terminal domain of the Flo11 protein from Saccharomyces cerevisiae is an adhesin without mannose-binding activity.	Mannose	95-102	Flo11p	Saccharomyces cerevisiae S288C	29-34
21893569-3	2012	ZG16p appeared to exhibit selective binding to alpha- and beta-linked mannose-polyacrylamide-biotin probes.	Mannose	70-77	zymogen granule protein 16	Homo sapiens	0-5
21893569-7	2012	Finally, we showed that ZG16p recognizes pathogenic Candida and Malassezia species in a polyvalent mannose-dependent manner.	Mannose	99-106	zymogen granule protein 16	Homo sapiens	24-29
21893569-8	2012	We propose that ZG16p is a novel member of mannose-specific JRLs, which recognizes pathogenic fungi through non-self polyvalent mannose in the digestive system.	Mannose	43-50	zymogen granule protein 16	Homo sapiens	16-21
21893569-8	2012	We propose that ZG16p is a novel member of mannose-specific JRLs, which recognizes pathogenic fungi through non-self polyvalent mannose in the digestive system.	Mannose	128-135	zymogen granule protein 16	Homo sapiens	16-21
23019433-1	2012	A series of 15 glycoside-derived tricarbonyl(eta(6)-arene)chromium complexes were prepared in 19-87% yield by heating fully acetylated or methylated aryl O-, S-, N- and C-glycosides of D-glucopyranose and D-mannopyranose with hexacarbonylchromium.	Mannose	205-220	endothelin receptor type A	Homo sapiens	45-48
22170046-5	2012	CASQ undergoes a unique degree of mannose trimming as it is trafficked from the proximal endoplasmic reticulum to the SR.	Mannose	34-41	calsequestrin 1	Homo sapiens	0-4
22148421-9	2012	Mannose-coated transducers display an excellent selectivity toward Con A in the presence of a large excess of bovine serum albumin (BSA).	Mannose	0-7	albumin	Homo sapiens	117-130
21664989-1	2012	The lectin pathway of the complement system is activated following the binding of carbohydrate-based ligands by recognition molecules such as mannose-binding lectin (MBL) or ficolins.	Mannose	142-149	mannose binding lectin 2	Homo sapiens	166-169
22158965-0	2012	Mannose 6 dephosphorylation of lysosomal proteins mediated by acid phosphatases Acp2 and Acp5.	Mannose	0-7	acid phosphatase 2, lysosomal	Mus musculus	80-84
22158965-0	2012	Mannose 6 dephosphorylation of lysosomal proteins mediated by acid phosphatases Acp2 and Acp5.	Mannose	0-7	acid phosphatase 5, tartrate resistant	Mus musculus	89-93
22257062-7	2012	Based on the fact that DCSIGN binds mannose- and fucose-based oligo- and polysaccharides, their structural mimics have been designed and proved to inhibit pathogen-DC-SIGN interaction.	Mannose	36-43	CD209 molecule	Homo sapiens	23-29
22832190-6	2012	RESULTS: The complex-glycosylated and mannose-rich CFTR isoforms were present in all non-CF specimens, whereas no or only the immature CFTR isoform was visible in CF samples.	Mannose	38-45	CF transmembrane conductance regulator	Homo sapiens	51-55
22507872-2	2012	We have shown previously that M. tuberculosis cell wall glycolipids, including mannose capped lipoarabinomannan (ManLAM), directly inhibit polyclonal murine CD4(+) T cell activation by blocking ZAP-70 phosphorylation.	Mannose	79-86	CD4 antigen	Mus musculus	157-160
23140167-2	2012	PGRP belongs to host pattern recognition receptors (PRRs) responsible for pathogen associated molecular patterns recognition, such as lipopolysaccharide, lipoteichoic acid, PGN, and mannose.	Mannose	182-189	peptidoglycan recognition protein 1	Homo sapiens	0-4
22257062-7	2012	Based on the fact that DCSIGN binds mannose- and fucose-based oligo- and polysaccharides, their structural mimics have been designed and proved to inhibit pathogen-DC-SIGN interaction.	Mannose	36-43	CD209 molecule	Homo sapiens	164-171
22160784-11	2012	Therefore, our results suggested that hERManI could recognize tertiary and/or quaternary structures of glycoproteins and remove more alpha-1,2 linked mannoses from misfolded glycoproteins in living cells.	Mannose	150-158	mannosidase alpha class 1B member 1	Homo sapiens	38-45
22187327-6	2012	This is further supported by the biochemical evidence that almost all N-glycans of N54Q ICAM-5 were digested by Endo glycosidase H and peptide:N-glycanase, indicating that almost all of them retain high-mannose-type structures in ER.	Mannose	203-210	intercellular adhesion molecule 5, telencephalin	Mus musculus	88-94
21835783-2	2012	Recent studies have shown that the complement system mediated by the mannan-binding protein (MBP), which is a C-type serum lectin recognizing mannose, fucose and N-acetylglucosamine residues, plays a critical role in the pathogenesis of ischemic acute renal failure.	Mannose	142-149	mannose-binding lectin (protein A) 1	Mus musculus	69-91
21835783-2	2012	Recent studies have shown that the complement system mediated by the mannan-binding protein (MBP), which is a C-type serum lectin recognizing mannose, fucose and N-acetylglucosamine residues, plays a critical role in the pathogenesis of ischemic acute renal failure.	Mannose	142-149	mannose-binding lectin (protein A) 1	Mus musculus	93-96
22080095-1	2012	BACKGROUND: Mannose-binding lectin (MBL) is a pattern-recognition molecule, which functions as a first line of host defense.	Mannose	12-19	mannose-binding lectin (protein C) 2	Mus musculus	36-39
22523468-0	2012	Mouse ficolin B has an ability to form complexes with mannose-binding lectin-associated serine proteases and activate complement through the lectin pathway.	Mannose	54-61	ficolin B	Mus musculus	6-15
22217303-6	2012	The estimated molecular masses of ABP-1 and ABP-2 were 2,000 kDa and 40-70 kDa, respectively, and their sugar compositions consisted mainly of glucose, mannose, xylose, and fructose.	Mannose	152-159	amine oxidase, copper-containing 1	Mus musculus	34-39
22970294-9	2012	Mannose rich N-glycosylated synaptophysin was detected by treating retinal lysates with endoglycosidase H followed by immunoblot analysis.	Mannose	0-7	synaptophysin	Rattus norvegicus	28-41
23139754-1	2012	Mannose-binding lectin (MBL) is a humoral pattern-recognition molecule important for host defense.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
22351007-1	2012	The effectiveness of mannose (using phosphomannose isomerase [pmi] gene) as a positive selection agent to preferably allow the growth of transformed oil palm embryogenic calli was successfully evaluated.	Mannose	21-28	mannose phosphate isomerase	Homo sapiens	36-60
22351007-1	2012	The effectiveness of mannose (using phosphomannose isomerase [pmi] gene) as a positive selection agent to preferably allow the growth of transformed oil palm embryogenic calli was successfully evaluated.	Mannose	21-28	mannose phosphate isomerase	Homo sapiens	62-65
23029318-0	2012	High mannose-binding antiviral lectin PFL from Pseudomonas fluorescens Pf0-1 promotes cell death of gastric cancer cell MKN28 via interaction with alpha2-integrin.	Mannose	5-12	profilin 2	Homo sapiens	38-41
22970294-12	2012	Mannose rich glycosylated synaptophysin was significantly increased after 1 month of STZ-diabetes compared to controls (p&lt;0.05).These data suggest that diabetes increases mRNA translation of synaptophysin in the retina, resulting in an accumulation of mannose rich glycosylated synaptophysin, a transient post-translational state of the protein.	Mannose	0-7	synaptophysin	Rattus norvegicus	26-39
22970294-12	2012	Mannose rich glycosylated synaptophysin was significantly increased after 1 month of STZ-diabetes compared to controls (p&lt;0.05).These data suggest that diabetes increases mRNA translation of synaptophysin in the retina, resulting in an accumulation of mannose rich glycosylated synaptophysin, a transient post-translational state of the protein.	Mannose	0-7	synaptophysin	Rattus norvegicus	194-207
22970294-12	2012	Mannose rich glycosylated synaptophysin was significantly increased after 1 month of STZ-diabetes compared to controls (p&lt;0.05).These data suggest that diabetes increases mRNA translation of synaptophysin in the retina, resulting in an accumulation of mannose rich glycosylated synaptophysin, a transient post-translational state of the protein.	Mannose	0-7	synaptophysin	Rattus norvegicus	194-207
22970294-12	2012	Mannose rich glycosylated synaptophysin was significantly increased after 1 month of STZ-diabetes compared to controls (p&lt;0.05).These data suggest that diabetes increases mRNA translation of synaptophysin in the retina, resulting in an accumulation of mannose rich glycosylated synaptophysin, a transient post-translational state of the protein.	Mannose	255-262	synaptophysin	Rattus norvegicus	26-39
22970294-12	2012	Mannose rich glycosylated synaptophysin was significantly increased after 1 month of STZ-diabetes compared to controls (p&lt;0.05).These data suggest that diabetes increases mRNA translation of synaptophysin in the retina, resulting in an accumulation of mannose rich glycosylated synaptophysin, a transient post-translational state of the protein.	Mannose	255-262	synaptophysin	Rattus norvegicus	194-207
22970294-12	2012	Mannose rich glycosylated synaptophysin was significantly increased after 1 month of STZ-diabetes compared to controls (p&lt;0.05).These data suggest that diabetes increases mRNA translation of synaptophysin in the retina, resulting in an accumulation of mannose rich glycosylated synaptophysin, a transient post-translational state of the protein.	Mannose	255-262	synaptophysin	Rattus norvegicus	194-207
22180208-7	2011	Interestingly, we found that desialylation caused increased binding of haptoglobin and hemopexin to mannose-specific lectins, pointing to the importance of identifying a signature of lectin-binding.	Mannose	100-107	haptoglobin	Homo sapiens	71-82
22157680-2	2011	In a hypomorphic Pmm2 mouse model, we were able to overcome embryonic lethality by feeding mannose to pregnant dams.	Mannose	91-98	phosphomannomutase 2	Mus musculus	17-21
21631672-2	2011	Frequently occurring MBL2 polymorphisms result in mannose-binding lectin deficiency, which increases susceptibility to infection.	Mannose	50-57	mannose binding lectin 2	Homo sapiens	21-25
22167226-1	2011	Mannose-binding lectin (MBL) is a key soluble pathogen recognition protein of the innate immune system that binds specific mannose-containing glycans on the surfaces of microbial agents and initiates complement activation via the lectin pathway.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
22167226-1	2011	Mannose-binding lectin (MBL) is a key soluble pathogen recognition protein of the innate immune system that binds specific mannose-containing glycans on the surfaces of microbial agents and initiates complement activation via the lectin pathway.	Mannose	123-130	mannose binding lectin 2	Homo sapiens	24-27
22167226-10	2011	Here, we show that mannose-binding lectin (MBL), a pattern recognition molecule that initiates the lectin pathway of complement activation, neutralized infection of all four DENV serotypes through complement activation-dependent and -independent pathways.	Mannose	19-26	mannose binding lectin 2	Homo sapiens	43-46
21866443-1	2011	Glucose, maltose, and mannose as sole carbon sources, induced synthesis of glucose dehydrogenase (GDH) in three strains of Pantoea with specific activities from 0.14 to 0.6 U/mg proteins.	Mannose	22-29	hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase	Homo sapiens	98-101
22180208-7	2011	Interestingly, we found that desialylation caused increased binding of haptoglobin and hemopexin to mannose-specific lectins, pointing to the importance of identifying a signature of lectin-binding.	Mannose	100-107	hemopexin	Homo sapiens	87-96
22019001-3	2011	This study focused on four polymorphisms in the mannose binding lectin gene (MBL2) and assessed their significance in tubal damage and female fertility by comparing genotype frequencies among 388 controls and women with tubal factor infertility (n=155) or previous ectopic pregnancy (n=178).	Mannose	48-55	mannose binding lectin 2	Homo sapiens	77-81
22093069-4	2011	EF2863 hydrolyzes the glycosidic bond between two N-acetylglucosamines (GlcNAc) in N-linked glycans of the high-mannose and hybrid type, releasing the glycan and leaving one GlcNAc attached to the protein.	Mannose	112-119	chitinase	Enterococcus faecalis V583	0-6
21917589-7	2011	At high EDEM1 levels, glycoprotein release is prevented and glycan interactions are no longer required, canceling the otherwise mandatory ERAD timing by mannose trimming and accelerating the targeting to degradation.	Mannose	153-160	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	8-13
22525502-10	2011	OPN from metastasis HCC tissues presented lower level of some specific glycan structures such as a2, 3- sialic acid, bisecting GlcNAc, biantennary, muti-antennary and high mannose type N-glycan structure.	Mannose	172-179	secreted phosphoprotein 1	Homo sapiens	0-3
22004528-8	2011	Interestingly, the Fc glycoforms carrying an unusual bisecting sugar moiety such as a mannose or a LacNAc moiety also demonstrated enhanced affinity to FcgammaRIIIa.	Mannose	86-93	Fc gamma receptor IIIa	Homo sapiens	152-164
22004528-10	2011	Our experimental data also showed that the alpha-linked mannose residues in the pentasaccharide Man3GlcNAc2 core was essential to maintain a high affinity of Fc to both FcgammaRIIIa and FcgammaRIIb.	Mannose	56-63	Fc gamma receptor IIIa	Homo sapiens	169-181
22004528-10	2011	Our experimental data also showed that the alpha-linked mannose residues in the pentasaccharide Man3GlcNAc2 core was essential to maintain a high affinity of Fc to both FcgammaRIIIa and FcgammaRIIb.	Mannose	56-63	Fc gamma receptor IIb	Homo sapiens	186-197
21834068-8	2011	The expression of beta1,2N-acetylglucosaminyltransferase I (GlcNAc-TI) mRNA, which converts high-mannose type N-glycans, was significantly increased in degraded mouse cartilage.	Mannose	97-104	mannoside acetylglucosaminyltransferase 1	Mus musculus	60-69
21834068-11	2011	CONCLUSION: These findings indicate that alterations in high-mannose type N-glycans and N-glycogenes in chondrocytes correlate with the release of MMP-13 and ADAMTS-5 during cartilage degradation.	Mannose	61-68	matrix metallopeptidase 13	Mus musculus	147-153
21834068-11	2011	CONCLUSION: These findings indicate that alterations in high-mannose type N-glycans and N-glycogenes in chondrocytes correlate with the release of MMP-13 and ADAMTS-5 during cartilage degradation.	Mannose	61-68	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)	Mus musculus	158-166
21645202-1	2011	Deficiency in human lysosomal alpha-mannosidase (MAN2B1) results in alpha-mannosidosis, a lysosomal storage disorder; patients present a wide range of neurological, immunological, and skeletal symptoms caused by a multisystemic accumulation of mannose-containing oligosaccharides.	Mannose	244-251	mannosidase alpha class 2B member 1	Homo sapiens	20-47
21645202-1	2011	Deficiency in human lysosomal alpha-mannosidase (MAN2B1) results in alpha-mannosidosis, a lysosomal storage disorder; patients present a wide range of neurological, immunological, and skeletal symptoms caused by a multisystemic accumulation of mannose-containing oligosaccharides.	Mannose	244-251	mannosidase alpha class 2B member 1	Homo sapiens	49-55
22505955-2	2011	Recent work has demonstrated that genetic-deficiency of Mannose-binding lectin(MBL) ameliorates reperfusion injury and improves outcome in the acute phase of stroke.	Mannose	56-63	mannose-binding lectin (protein C) 2	Mus musculus	79-82
22008821-6	2011	Moreover, addition of mannose to an IBV vaccine altered both vaccine-induced changes in circulating T-cell populations and IBV specific vaccine and infection-induced antibody responses in chickens with high serum MBL levels.	Mannose	22-29	mannose binding lectin 2	Gallus gallus	213-216
21949237-4	2011	Both PMM2 and MPI compete for the same substrate, Man-6-P. Daily mannose doses reverse most of the symptoms of MPI-deficient CDG-Ib patients.	Mannose	65-72	phosphomannomutase 2	Homo sapiens	5-9
21911496-4	2011	TNFalpha treatment of human umbilical vein endothelial cells increased surface expression of high mannose/hybrid N-glycans.	Mannose	98-105	tumor necrosis factor	Homo sapiens	0-8
21911496-7	2011	A panel of structurally distinct PPARgamma agonists all decreased TNFalpha-dependent expression of endothelial high mannose/hybrid N-glycans.	Mannose	116-123	peroxisome proliferator activated receptor gamma	Homo sapiens	33-42
21911496-7	2011	A panel of structurally distinct PPARgamma agonists all decreased TNFalpha-dependent expression of endothelial high mannose/hybrid N-glycans.	Mannose	116-123	tumor necrosis factor	Homo sapiens	66-74
21911496-8	2011	Using rosiglitazone as a model PPARgamma agonist, which decreased TNFalpha-induced high mannose N-glycan expression, we demonstrate a role for these carbohydrate residues in THP-1 rolling and adhesion that is independent of endothelial surface adhesion molecule expression (ICAM-1 and E-selectin).	Mannose	88-95	peroxisome proliferator activated receptor gamma	Homo sapiens	31-40
21911496-8	2011	Using rosiglitazone as a model PPARgamma agonist, which decreased TNFalpha-induced high mannose N-glycan expression, we demonstrate a role for these carbohydrate residues in THP-1 rolling and adhesion that is independent of endothelial surface adhesion molecule expression (ICAM-1 and E-selectin).	Mannose	88-95	tumor necrosis factor	Homo sapiens	66-74
21911496-9	2011	Data from N-glycan processing gene arrays identified alpha-mannosidases (MAN1A2 and MAN1C1) as targets for down-regulation by TNFalpha, which was reversed by rosiglitazone, a result consistent with altered high mannose/hybrid N-glycan epitopes.	Mannose	211-218	mannosidase alpha class 1A member 2	Homo sapiens	73-79
21911496-9	2011	Data from N-glycan processing gene arrays identified alpha-mannosidases (MAN1A2 and MAN1C1) as targets for down-regulation by TNFalpha, which was reversed by rosiglitazone, a result consistent with altered high mannose/hybrid N-glycan epitopes.	Mannose	211-218	mannosidase alpha class 1C member 1	Homo sapiens	84-90
21911496-9	2011	Data from N-glycan processing gene arrays identified alpha-mannosidases (MAN1A2 and MAN1C1) as targets for down-regulation by TNFalpha, which was reversed by rosiglitazone, a result consistent with altered high mannose/hybrid N-glycan epitopes.	Mannose	211-218	tumor necrosis factor	Homo sapiens	126-134
21911456-8	2011	Mcl-1 loss and cell death were prevented by downregulation of the endoplasmic reticulum (ER) stress-induced protein ATF4 and by incubating cells in the presence of mannose, which reverted 2-DG-induced ER stress but not ATP depletion.	Mannose	164-171	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	0-5
21471331-8	2011	Microsomes containing heterologously expressed CSLD5 transferred mannose from GDP-mannose onto endogenous acceptors.	Mannose	65-72	cellulose synthase-like D5	Arabidopsis thaliana	47-52
21471331-10	2011	With monosaccharides as exogenous acceptors, microsomal preparations from CSLD5-expressing plants mediated the transfer of mannose from GDP-mannose onto mannose.	Mannose	123-130	cellulose synthase-like D5	Arabidopsis thaliana	74-79
21471331-10	2011	With monosaccharides as exogenous acceptors, microsomal preparations from CSLD5-expressing plants mediated the transfer of mannose from GDP-mannose onto mannose.	Mannose	140-147	cellulose synthase-like D5	Arabidopsis thaliana	74-79
21862481-3	2011	A mannose-specific JRL (mJRL)-like gene (TaJRLL1) that is mainly expressed in stem and spike and encodes a protein with two jacalin-like lectin domains was identified in wheat.	Mannose	2-9	mannose/glucose-specific lectin	Triticum aestivum	41-48
22102941-6	2011	DC-SIGN, a mannose-binding C-type lectin expressed on cells in the mucosal tissue of the rectum, uterus and cervix, facilitates early HIV-1 infection after sexual transmission.	Mannose	11-18	CD209 molecule	Homo sapiens	0-7
21882825-6	2011	Blocking the mannose and CIRE receptors prior to the addition of functionalized nanoparticles to the culture inhibited the increased surface expression of MHC II, CD40 and CD86.	Mannose	13-20	CD40 molecule	Homo sapiens	163-167
21835174-2	2011	Prosaposin, the precursor of four sphingolipid activator proteins, is transported from the trans-Golgi network (TGN) to lysosomes as a partially glycosylated (65 kDa) protein with high-mannose/hybrid oligosaccharides.	Mannose	185-192	prosaposin	Homo sapiens	0-10
21882825-6	2011	Blocking the mannose and CIRE receptors prior to the addition of functionalized nanoparticles to the culture inhibited the increased surface expression of MHC II, CD40 and CD86.	Mannose	13-20	CD86 molecule	Homo sapiens	172-176
21838223-2	2011	Robust levels of selectivity for the equatorial OH group of cis-1,2-diol motifs are demonstrated in reactions of seven acceptors derived from galactose, mannose, fucose, and arabinose using a variety of glycosyl halide donors.	Mannose	153-160	suppressor of cytokine signaling 1	Homo sapiens	60-65
21622726-7	2011	These mannose residues were not observed in wild-type cells, suggesting that the addition of these unique mannoses occurred as a compensation of Och1 defect.	Mannose	6-13	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	145-149
21622726-7	2011	These mannose residues were not observed in wild-type cells, suggesting that the addition of these unique mannoses occurred as a compensation of Och1 defect.	Mannose	106-114	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	145-149
21865552-1	2011	Mannose-binding lectin (MBL)-associated serine proteases (MASPs) are responsible for activation of the lectin complement pathway.	Mannose	0-7	mannose-binding lectin (protein C) 2	Mus musculus	24-27
21188635-3	2011	Previously, we described an Arabidopsis alg3-2 glycosylation mutant in which aberrant Man(5)GlcNAc(2) mannose type N-glycans are transferred to proteins.	Mannose	102-109	asparagine-linked glycosylation 3	Arabidopsis thaliana	40-44
21741082-8	2011	FACS experiments confirmed that transfection using these nanoparticles is mannose-dependent, supporting the potential of the approach towards vectorized gene delivery.	Mannose	74-81	acyl-CoA synthetase long-chain family member 1	Mus musculus	0-4
21715597-0	2011	Removal of two high-mannose N-linked glycans on gp120 renders human immunodeficiency virus 1 largely resistant to the carbohydrate-binding agent griffithsin.	Mannose	20-27	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	48-53
21920605-7	2011	Antibodies against mannose binding lectin inhibited C4 deposition and SAG induced no C4 deposition in MBL deficient sera showing SAG activated complement through the MBL pathway.	Mannose	19-26	deleted in malignant brain tumors 1	Homo sapiens	70-73
21819116-2	2011	We describe here a highly convergent chemoenzymatic synthesis of the monoglucosylated glycoforms of bovine ribonuclease (RNase) as specific ligands of lectin-like chaperones calnexin (CNX) and calreticulin (CRT) that are known to recognize the monoglucosylated high-mannose oligosaccharide component of glycoproteins in protein folding.	Mannose	266-273	calnexin	Bos taurus	174-182
21819116-2	2011	We describe here a highly convergent chemoenzymatic synthesis of the monoglucosylated glycoforms of bovine ribonuclease (RNase) as specific ligands of lectin-like chaperones calnexin (CNX) and calreticulin (CRT) that are known to recognize the monoglucosylated high-mannose oligosaccharide component of glycoproteins in protein folding.	Mannose	266-273	calnexin	Bos taurus	184-187
22082268-0	2011	Influence of placental mannose/n-acetyl glucosamine-binding proteins on the interaction of insulin and insulin-like growth factors with their receptors.	Mannose	23-30	insulin	Homo sapiens	91-98
21723917-6	2011	OS-9 and the MPRs use the same four residues (Gln, Arg, Glu, and Tyr) to bind mannose.	Mannose	78-85	OS9 endoplasmic reticulum lectin	Homo sapiens	0-4
22082268-0	2011	Influence of placental mannose/n-acetyl glucosamine-binding proteins on the interaction of insulin and insulin-like growth factors with their receptors.	Mannose	23-30	insulin	Homo sapiens	103-110
21723917-2	2011	Many MRH domains act as lectins and bind specific phosphorylated (MPRs) or non-phosphorylated (glucosidase II beta-subunit, XTP3-B and OS-9) high mannose-type N-glycans.	Mannose	146-153	endoplasmic reticulum lectin 1	Homo sapiens	95-130
21723917-2	2011	Many MRH domains act as lectins and bind specific phosphorylated (MPRs) or non-phosphorylated (glucosidase II beta-subunit, XTP3-B and OS-9) high mannose-type N-glycans.	Mannose	146-153	OS9 endoplasmic reticulum lectin	Homo sapiens	135-139
22082268-2	2011	Mannose/N-acetyl-glucosamine (Man/GlcNAc)-binding proteins from placenta were isolated and their reactivity towards placental insulin and insulin-like growth factor receptors (IR and IGF-Rs) was analyzed.	Mannose	0-7	insulin	Homo sapiens	126-133
22082268-2	2011	Mannose/N-acetyl-glucosamine (Man/GlcNAc)-binding proteins from placenta were isolated and their reactivity towards placental insulin and insulin-like growth factor receptors (IR and IGF-Rs) was analyzed.	Mannose	0-7	insulin	Homo sapiens	138-145
21540232-4	2011	In this side-by-side study DC-SIGN was found to preferentially bind internal mannose residues of high-mannose-type saccharides and the fucose-containing blood-type antigens H, A, B, Le(a), Le(b) Le(x), Le(y), sialyl-Le(a) as well as sulfatated derivatives of Le(a) and Le(x).	Mannose	77-84	CD209 molecule	Homo sapiens	27-34
21697467-0	2011	Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding site.	Mannose	15-22	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	62-67
21697467-0	2011	Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding site.	Mannose	15-22	CD4 molecule	Homo sapiens	80-83
21683706-1	2011	Phosphomannose isomerase (PMI) catalyzes the reversible interconversion of fructose 6-phosphate (Fru-6-P) and mannose 6-phosphate (Man-6-P), providing a link between glycolysis and the mannose metabolic pathway.	Mannose	7-14	mannose phosphate isomerase	Homo sapiens	26-29
21540232-4	2011	In this side-by-side study DC-SIGN was found to preferentially bind internal mannose residues of high-mannose-type saccharides and the fucose-containing blood-type antigens H, A, B, Le(a), Le(b) Le(x), Le(y), sialyl-Le(a) as well as sulfatated derivatives of Le(a) and Le(x).	Mannose	102-109	CD209 molecule	Homo sapiens	27-34
21540232-5	2011	In contrast, Langerin appeared to recognize a different spectrum of compounds, especially those containing terminal mannose, terminal N-acetylglucosamine and 6-sulfogalactose residues, but also the blood-type antigens H, A and B.	Mannose	116-123	CD207 molecule	Homo sapiens	13-21
21540232-7	2011	Notably, Ca(2+)-independent glycan-binding activity of Langerin could not be detected either by probing the glycan array or by isothermal titration calorimetry of the CRD with mannose and mannobiose.	Mannose	176-183	CD207 molecule	Homo sapiens	55-63
21694730-2	2011	The cooperative binding of three segments of AH to three high mannose-type glycans (HMTGs) of HIV-1 gp120 generates specific and strong anti-HIV activity.	Mannose	62-69	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	100-105
22007480-0	2011	[Mannose-binding lectin (MBL) inhibits human cytomegalovirus infection of human MD-DC].	Mannose	1-8	mannose-binding lectin family member 3, pseudogene	Homo sapiens	25-28
22007480-1	2011	OBJECTIVE: To explore the inhibitory effect of different sources, different concentrations of Mannose-binding lectin (MBL) on human cytomegalovirus infection of human MD-DC cells.	Mannose	94-101	mannose-binding lectin family member 3, pseudogene	Homo sapiens	118-121
21799112-2	2011	This antiviral activity is attributed to two homologous carbohydrate binding sites that specifically bind high mannose glycosylation present on envelope glycoproteins such as HIV-1 gp120.	Mannose	111-118	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	181-186
21659516-1	2011	Pannexin1 (Panx1) is an integral membrane protein comprised of three species as follows: an unglycosylated core-Gly0, a high mannose-Gly1, and a complex glycosylated Gly2 species.	Mannose	125-132	pannexin 1	Homo sapiens	0-9
21659516-1	2011	Pannexin1 (Panx1) is an integral membrane protein comprised of three species as follows: an unglycosylated core-Gly0, a high mannose-Gly1, and a complex glycosylated Gly2 species.	Mannose	125-132	pannexin 1	Homo sapiens	11-16
21659516-4	2011	Enzymatic digestion and immunolabeling assays revealed that the Panx1(T307)-RFP was glycosylated primarily to the high mannose species consistent with its retention in the endoplasmic reticulum.	Mannose	119-126	pannexin 1	Homo sapiens	64-69
21659516-4	2011	Enzymatic digestion and immunolabeling assays revealed that the Panx1(T307)-RFP was glycosylated primarily to the high mannose species consistent with its retention in the endoplasmic reticulum.	Mannose	119-126	tripartite motif containing 27	Homo sapiens	76-79
21489885-1	2011	Mannose-binding lectin (MBL) initiates complement on Trypanosoma cruzi through the MBL-associated serine protease 2 (MASP2).	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
21613225-0	2011	Extensive mannose phosphorylation on leukemia inhibitory factor (LIF) controls its extracellular levels by multiple mechanisms.	Mannose	10-17	LIF interleukin 6 family cytokine	Homo sapiens	37-63
21613225-0	2011	Extensive mannose phosphorylation on leukemia inhibitory factor (LIF) controls its extracellular levels by multiple mechanisms.	Mannose	10-17	LIF interleukin 6 family cytokine	Homo sapiens	65-68
21613225-3	2011	In this study, we investigated the mannose phosphorylation status of leukemia inhibitory factor (LIF), a previously identified high affinity ligand for the cation-independent mannose 6-phosphate receptor (CI-MPR), and we analyzed the effects of this modification on its secretion and uptake in cultured cells.	Mannose	35-42	LIF interleukin 6 family cytokine	Homo sapiens	69-95
21613225-3	2011	In this study, we investigated the mannose phosphorylation status of leukemia inhibitory factor (LIF), a previously identified high affinity ligand for the cation-independent mannose 6-phosphate receptor (CI-MPR), and we analyzed the effects of this modification on its secretion and uptake in cultured cells.	Mannose	35-42	LIF interleukin 6 family cytokine	Homo sapiens	97-100
21613225-8	2011	Using mouse embryonic stem cells, we showed that the mannose phosphorylation of LIF mediates its internalization thereby reducing extracellular levels and stimulating embryonic stem cell differentiation.	Mannose	53-60	leukemia inhibitory factor	Mus musculus	80-83
21613225-9	2011	Finally, immunofluorescence experiments indicate that LIF is targeted directly to lysosomes following its biosynthesis, providing another mechanism whereby mannose phosphorylation serves to control extracellular levels of LIF.	Mannose	156-163	LIF interleukin 6 family cytokine	Homo sapiens	54-57
21613225-9	2011	Finally, immunofluorescence experiments indicate that LIF is targeted directly to lysosomes following its biosynthesis, providing another mechanism whereby mannose phosphorylation serves to control extracellular levels of LIF.	Mannose	156-163	LIF interleukin 6 family cytokine	Homo sapiens	222-225
21253888-4	2011	When the LAT1 or LAT2 were expressed in an S. cerevisiae mutant where the main hexose transporters were deleted, the L: -arabinose transporters could not restore growth on D: -glucose, D: -fructose, D: -mannose or D: -galactose.	Mannose	203-210	dihydrolipoyllysine-residue acetyltransferase	Saccharomyces cerevisiae S288C	9-13
21489885-1	2011	Mannose-binding lectin (MBL) initiates complement on Trypanosoma cruzi through the MBL-associated serine protease 2 (MASP2).	Mannose	0-7	mannose binding lectin 2	Homo sapiens	83-86
21489885-1	2011	Mannose-binding lectin (MBL) initiates complement on Trypanosoma cruzi through the MBL-associated serine protease 2 (MASP2).	Mannose	0-7	MBL associated serine protease 2	Homo sapiens	117-122
21314946-7	2011	Also, epitope mapping experiments revealed that GNA and the mannose-specific mAb 2G12 can independently bind from GNAmaize to gp120, whereas GNAmaize cannot efficiently bind to gp120 that contained prebound PHA-E (GlcNAcbeta1,2man specific) or SNA (NeuAcalpha2,6X specific).	Mannose	60-67	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	126-131
21482189-3	2011	In human alveolar A549 epithelial cells, lipoglycans of M. tuberculosis, in particular mannose-capped lipoarabinomannan and phosphatidyl-myo-inositol mannosides, were strong inducers of hepcidin mRNA.	Mannose	87-94	hepcidin antimicrobial peptide	Mus musculus	186-194
21470685-7	2011	Mac-1-dependent, but not Mac-1-independent, transmigration was significantly reduced in the presence of N-acetyl-d-glucosamine and d-mannose, the saccharides that disrupt uPAR/Mac-1 association, but was unaffected in the presence of control saccharides (d-sorbitol and sucrose).	Mannose	131-140	integrin subunit alpha M	Homo sapiens	0-5
21470685-7	2011	Mac-1-dependent, but not Mac-1-independent, transmigration was significantly reduced in the presence of N-acetyl-d-glucosamine and d-mannose, the saccharides that disrupt uPAR/Mac-1 association, but was unaffected in the presence of control saccharides (d-sorbitol and sucrose).	Mannose	131-140	plasminogen activator, urokinase receptor	Homo sapiens	171-175
21384882-3	2011	In a second step, we demonstrate that the presence of functional amine groups in the outer shell of apoferritin allows functionalization with two carbohydrates, N-acetyl-D-glucosamine and d-mannose.	Mannose	188-197	ferritin heavy chain 1	Homo sapiens	100-111
21106560-1	2011	We have recently demonstrated that the mannose-binding lectins, namely banana lectin (BL) and garlic lectin (GL), interacted with the insulin receptors on M210B4 cells--an established mesenchymal cell line of murine marrow origin--and initiate mitogen-activated protein kinase kinase (MEK)-dependent extracellular signal-regulated kinase (ERK) signaling in them.	Mannose	39-46	midkine	Mus musculus	244-283
21106560-1	2011	We have recently demonstrated that the mannose-binding lectins, namely banana lectin (BL) and garlic lectin (GL), interacted with the insulin receptors on M210B4 cells--an established mesenchymal cell line of murine marrow origin--and initiate mitogen-activated protein kinase kinase (MEK)-dependent extracellular signal-regulated kinase (ERK) signaling in them.	Mannose	39-46	midkine	Mus musculus	285-288
21106560-1	2011	We have recently demonstrated that the mannose-binding lectins, namely banana lectin (BL) and garlic lectin (GL), interacted with the insulin receptors on M210B4 cells--an established mesenchymal cell line of murine marrow origin--and initiate mitogen-activated protein kinase kinase (MEK)-dependent extracellular signal-regulated kinase (ERK) signaling in them.	Mannose	39-46	mitogen-activated protein kinase 1	Mus musculus	300-337
21106560-1	2011	We have recently demonstrated that the mannose-binding lectins, namely banana lectin (BL) and garlic lectin (GL), interacted with the insulin receptors on M210B4 cells--an established mesenchymal cell line of murine marrow origin--and initiate mitogen-activated protein kinase kinase (MEK)-dependent extracellular signal-regulated kinase (ERK) signaling in them.	Mannose	39-46	mitogen-activated protein kinase 1	Mus musculus	339-342
21512604-3	2011	Synthetic PIM/LM/LAM substructures are useful biochemical tools to delineate and dissect the fine details of mannose glycophospholipid biosynthesis and their interactions with host cells.	Mannose	109-116	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	10-13
21273394-1	2011	All mammals have 50-100 muM mannose in their blood.	Mannose	28-35	latexin	Homo sapiens	24-27
21273394-7	2011	Under physiological conditions, incoming mannose is more accessible to hexokinase, whereas mannose released within the cells is protected from HK and therefore has a different fate.	Mannose	41-48	hexokinase 1	Homo sapiens	71-81
21384556-2	2011	According to the results of SPR spectroscopy, the mannose-conjugated polyrotaxanes show a higher response than any other mannose conjugate on both surfaces of high- and low-density Con A.	Mannose	50-57	sepiapterin reductase	Homo sapiens	28-31
21380727-1	2011	Mannose-binding lectin was identified as a substrate of tankyrase 2, an enzyme that catalyzes poly(ADP-ribosyl)ation.	Mannose	0-7	tankyrase 2	Homo sapiens	56-67
21380727-4	2011	Using immunoblot analysis and radioactive labeling, we detected tankyrase-2-dependent poly(ADP-ribosyl)ation of mannose-binding lectin.	Mannose	112-119	tankyrase 2	Homo sapiens	64-75
21380727-7	2011	The latter effect was observed using mannose-binding lectin out of human serum, which is free from keratin 1.	Mannose	37-44	keratin 1	Homo sapiens	99-108
21490929-1	2011	BACKGROUND: Allium sativum leaf agglutinin (ASAL) is a 25-kDa homodimeric, insecticidal, mannose binding lectin whose subunits are assembled by the C-terminal exchange process.	Mannose	89-96	argininosuccinate lyase	Mus musculus	44-48
21490929-7	2011	Mannose binding assay confirmed that molecular mannose binds efficiently to both mASAL and ASAL.	Mannose	0-7	argininosuccinate lyase	Mus musculus	81-86
21490929-7	2011	Mannose binding assay confirmed that molecular mannose binds efficiently to both mASAL and ASAL.	Mannose	0-7	argininosuccinate lyase	Mus musculus	82-86
21490929-7	2011	Mannose binding assay confirmed that molecular mannose binds efficiently to both mASAL and ASAL.	Mannose	47-54	argininosuccinate lyase	Mus musculus	81-86
21490929-7	2011	Mannose binding assay confirmed that molecular mannose binds efficiently to both mASAL and ASAL.	Mannose	47-54	argininosuccinate lyase	Mus musculus	82-86
21251052-3	2011	In the present study, the BM45- and VIN13-derived HSP30p-FLO11 wine yeast transformants were observed to be exclusively and strongly flocculent under authentic red wine-making conditions, thus suggesting that this specific fermentation environment specifically contributes to the development of a flocculent phenotype, which is insensitive to either glucose or mannose.	Mannose	361-368	Flo11p	Saccharomyces cerevisiae S288C	57-62
21045008-2	2011	MBL binds to glycoconjugates containing mannose, fucose or N-acetylglucosamine that are present in a wide variety of bacteria, viruses and fungi.	Mannose	40-47	mannose binding lectin 2	Homo sapiens	0-3
21192229-1	2011	OBJECTIVE: This study investigates the role of mannose-binding lectin (MBL) in the susceptibility to HIV-1 infection analyzing polymorphisms located at the MBL2 promoter and exon 1 regions.	Mannose	47-54	mannose binding lectin 2	Homo sapiens	71-74
21347387-10	2011	Collectively, these results suggest that mannose containing oligosaccharides within human non-specific secretory IgA can alter important virulence phenotypes of Vibrio cholerae such as biofilm formation, without affecting viability of the microorganism.	Mannose	41-48	CD79a molecule	Homo sapiens	113-116
21268157-9	2011	This information is of key importance for the development of multivalent synthetic gp120 high-mannose glycoconjugate mimics in the context of vaccine development.	Mannose	94-101	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	83-88
21062743-0	2011	Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps.	Mannose	0-7	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	65-70
21112338-2	2011	Langerin binds to an unusually diverse number of endogenous and pathogenic cell surface carbohydrates, including mannose-containing O-specific polysaccharides derived from bacterial lipopolysaccharides identified here by probing a microarray of bacterial polysaccharides.	Mannose	113-120	CD207 molecule	Homo sapiens	0-8
21112338-3	2011	Crystal structures of the carbohydrate-recognition domain from human langerin bound to a series of oligomannose compounds, the blood group B antigen, and a fragment of beta-glucan reveal binding to mannose, fucose, and glucose residues by Ca(2+) coordination of vicinal hydroxyl groups with similar stereochemistry.	Mannose	104-111	CD207 molecule	Homo sapiens	69-77
21062743-0	2011	Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps.	Mannose	0-7	endoplasmic reticulum lectin 1	Homo sapiens	74-80
21062743-2	2011	EDEM1 was initially suggested to bind N-glycans after mannose trimming, a role presently ascribed to the lectins OS9 and XTP3-B, because of their in vitro affinities for trimmed oligosaccharides.	Mannose	54-61	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	0-5
21062743-10	2011	However, substrate association with XTP3-B was still dependent on mannose trimming upon SEL1L knockdown.	Mannose	66-73	endoplasmic reticulum lectin 1	Homo sapiens	36-42
21062743-10	2011	However, substrate association with XTP3-B was still dependent on mannose trimming upon SEL1L knockdown.	Mannose	66-73	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase	Homo sapiens	88-93
21062743-11	2011	Our results suggest that mannose trimming enables delivery of a substrate glycoprotein from EDEM1 to late ERAD steps through association with XTP3-B.	Mannose	25-32	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	92-97
21062743-11	2011	Our results suggest that mannose trimming enables delivery of a substrate glycoprotein from EDEM1 to late ERAD steps through association with XTP3-B.	Mannose	25-32	endoplasmic reticulum lectin 1	Homo sapiens	142-148
21047777-3	2011	This study describes crystal structures of calcium-dependent complexes of the C-terminal neck and carbohydrate recognition domain of SP-A with d-mannose, D-alpha-methylmannose, and glycerol, which represent subdomains of glycans on pathogen surfaces.	Mannose	143-152	surfactant protein A1	Homo sapiens	133-137
21110947-7	2011	The putative sugar-binding site of ZG16p is occupied by a glycerol molecule, mimicking the mannose bound to Jacalin-related mannose-binding-type plant lectins such as Banlec.	Mannose	91-98	zymogen granule protein 16	Homo sapiens	35-40
21110947-7	2011	The putative sugar-binding site of ZG16p is occupied by a glycerol molecule, mimicking the mannose bound to Jacalin-related mannose-binding-type plant lectins such as Banlec.	Mannose	124-131	zymogen granule protein 16	Homo sapiens	35-40
21110947-8	2011	ZG16b also has a beta-prism fold, but some amino acid residues of the putative sugar-binding site differ from those of the mannose-type binding site suggesting altered preference.	Mannose	123-130	zymogen granule protein 16B	Homo sapiens	0-5
22254261-4	2011	The voltage-dependence of hERG channels steady-state activation and inactivation under four glycosylation conditions, i.e., full glycosylation, reduced sialylation, mannose-rich and N-Glycanase treated, demonstrated that reduced glycosylation modulates hERG channel gating.	Mannose	165-172	ETS transcription factor ERG	Homo sapiens	26-30
21288816-1	2011	Mannose-binding lectin (MBL) targets diverse microorganisms for phagocytosis and complement-mediated lysis by binding specific surface glycans.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
21674342-0	2011	On-resin convergent synthesis of a glycopeptide from HIV gp120 containing a high mannose type N-linked oligosaccharide.	Mannose	81-88	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	57-62
21265802-4	2011	FimH can recognize equally the (single) high-mannose glycan on uroplakin Ia, on the urinary defence protein uromodulin or Tamm-Horsfall glycoprotein and on the intestinal GP2 glycoprotein present in Peyer"s patches.	Mannose	45-52	uroplakin 1A	Homo sapiens	63-75
20969732-9	2011	However, during electroneutral mannose absorption or electrogenic alpha-D-methyl glucoside absorption, Cl(-)(IN) /HCO3(-) (OUT) exchange was reduced in both Pat-1 KO and Dra KO villi.	Mannose	31-38	solute carrier family 26, member 6	Mus musculus	157-162
21076009-7	2011	The binding of N-Flo1p to D-mannose, alpha-methyl-D-mannoside, various dimannoses, and mannan confirmed that the N-terminal domain of Flo1p is indeed responsible for the sugar-binding activity of the protein.	Mannose	26-35	flocculin FLO1	Saccharomyces cerevisiae S288C	17-22
21076009-7	2011	The binding of N-Flo1p to D-mannose, alpha-methyl-D-mannoside, various dimannoses, and mannan confirmed that the N-terminal domain of Flo1p is indeed responsible for the sugar-binding activity of the protein.	Mannose	26-35	flocculin FLO1	Saccharomyces cerevisiae S288C	134-139
21674342-7	2011	This approach has been applied to the solid-phase synthesis of the N-linked high mannose glycosylated form of peptide T (ASTTTNYT), a fragment of the HIV-1 envelope glycoprotein gp120.	Mannose	81-88	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	178-183
22163010-3	2011	Many tumor antigens are heavily glycosylated, such as tumoral mucins, and/or attached to tumor cells by mannose residue-containing glycolipids (GPI anchors), as for example mesothelin and the family of carcinoembryonic antigen (CEA).	Mannose	104-111	CEA cell adhesion molecule 3	Homo sapiens	202-226
22163010-3	2011	Many tumor antigens are heavily glycosylated, such as tumoral mucins, and/or attached to tumor cells by mannose residue-containing glycolipids (GPI anchors), as for example mesothelin and the family of carcinoembryonic antigen (CEA).	Mannose	104-111	CEA cell adhesion molecule 3	Homo sapiens	228-231
21886772-8	2011	FKRP contains N-glycan of high mannose and/or hybrid type; however, FKRP N-glycosylation is not required for FKRP homodimer or multimer formation.	Mannose	31-38	fukutin related protein	Homo sapiens	0-4
21355310-0	2011	[Influence of high glucose and mannose binding lectin complement pathway activation to IL-6 and TNF-alpha"s expression by human renal glomerular endothelial cells].	Mannose	31-38	interleukin 6	Homo sapiens	87-91
21695215-1	2011	Structural variants of the Mannose Binding Lectin (MBL) cause quantitative and qualitative functional deficiencies, which are associated with various patterns of susceptibility to infectious diseases and other disorders.	Mannose	27-34	mannose binding lectin 2	Homo sapiens	51-54
21340397-1	2011	INTRODUCTION: The present study investigated the association between mannose-binding lectin (MBL) gene polymorphism and serum levels with infection by HIV-1.	Mannose	69-76	mannose binding lectin 2	Homo sapiens	93-96
21355310-0	2011	[Influence of high glucose and mannose binding lectin complement pathway activation to IL-6 and TNF-alpha"s expression by human renal glomerular endothelial cells].	Mannose	31-38	tumor necrosis factor	Homo sapiens	96-105
21355310-1	2011	OBJECTIVE: To investigate the effect of high glucose and mannose binding lectin (MBL) complement pathway activation"s effect on expression of Interleukin-6 (IL-6) and Tumor necrosis factor-alpha (TNF-alpha) from human renal glomerular endothelial cells (HRGEC), to explore unknown pathogenesy of diabetic nephropathy.	Mannose	57-64	mannose binding lectin 2	Homo sapiens	81-84
21355310-1	2011	OBJECTIVE: To investigate the effect of high glucose and mannose binding lectin (MBL) complement pathway activation"s effect on expression of Interleukin-6 (IL-6) and Tumor necrosis factor-alpha (TNF-alpha) from human renal glomerular endothelial cells (HRGEC), to explore unknown pathogenesy of diabetic nephropathy.	Mannose	57-64	interleukin 6	Homo sapiens	142-155
21355310-1	2011	OBJECTIVE: To investigate the effect of high glucose and mannose binding lectin (MBL) complement pathway activation"s effect on expression of Interleukin-6 (IL-6) and Tumor necrosis factor-alpha (TNF-alpha) from human renal glomerular endothelial cells (HRGEC), to explore unknown pathogenesy of diabetic nephropathy.	Mannose	57-64	interleukin 6	Homo sapiens	157-161
21355310-1	2011	OBJECTIVE: To investigate the effect of high glucose and mannose binding lectin (MBL) complement pathway activation"s effect on expression of Interleukin-6 (IL-6) and Tumor necrosis factor-alpha (TNF-alpha) from human renal glomerular endothelial cells (HRGEC), to explore unknown pathogenesy of diabetic nephropathy.	Mannose	57-64	tumor necrosis factor	Homo sapiens	167-194
21355310-1	2011	OBJECTIVE: To investigate the effect of high glucose and mannose binding lectin (MBL) complement pathway activation"s effect on expression of Interleukin-6 (IL-6) and Tumor necrosis factor-alpha (TNF-alpha) from human renal glomerular endothelial cells (HRGEC), to explore unknown pathogenesy of diabetic nephropathy.	Mannose	57-64	tumor necrosis factor	Homo sapiens	196-205
21182784-1	2010	BACKGROUND: Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, inhibits influenza A virus infection in vitro.	Mannose	12-19	mannose-binding lectin (protein C) 2	Mus musculus	36-39
22168041-2	2011	In this interaction IL2 acts as lectin binding with two-antenna terminals of 5 or 6 mannose residues in one and the same region of immunoglobulin.	Mannose	84-91	interleukin 2	Homo sapiens	20-23
20817851-1	2010	The LMAN1-MCFD2 (lectin, mannose binding 1/multiple coagulation factor deficiency protein 2) cargo receptor complex transports coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment (ERGIC).	Mannose	25-32	lectin, mannose binding 1	Homo sapiens	4-9
20817851-1	2010	The LMAN1-MCFD2 (lectin, mannose binding 1/multiple coagulation factor deficiency protein 2) cargo receptor complex transports coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment (ERGIC).	Mannose	25-32	multiple coagulation factor deficiency 2, ER cargo receptor complex subunit	Homo sapiens	10-15
20817851-1	2010	The LMAN1-MCFD2 (lectin, mannose binding 1/multiple coagulation factor deficiency protein 2) cargo receptor complex transports coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment (ERGIC).	Mannose	25-32	coagulation factor VIII	Homo sapiens	164-169
20696204-7	2010	More interestingly, Ssalpha-man removes mannose residues from the glycosidic moiety of the bovine pancreatic ribonuclease B, suggesting that it could process mannosylated proteins also in vivo.	Mannose	40-47	tripartite motif containing 21	Homo sapiens	20-27
21209725-5	2010	After purification, the enzyme is modified to reveal terminal mannose residues which facilitate selective uptake of the protein, imiglucerase (Cerezyme( )), in macrophage-rich tissues.	Mannose	62-69	glucosylceramidase beta	Homo sapiens	129-141
21240668-0	2010	Seizures and stupor during intravenous mannose therapy in a patient with CDG syndrome type 1b (MPI-CDG).	Mannose	39-46	mannose phosphate isomerase	Homo sapiens	95-98
21240668-2	2010	Dietary supplementation of mannose can reverse clinical symptoms by entering the N-glycosylation pathway downstream of MPI.	Mannose	27-34	mannose phosphate isomerase	Homo sapiens	119-122
21240668-3	2010	When oral intake of mannose in patients with MPI-CDG is not possible, e.g. due to surgery, mannose has to be given intravenously.	Mannose	20-27	mannose phosphate isomerase	Homo sapiens	45-48
21240668-4	2010	We report a patient with MPI-CDG on intravenous mannose therapy that showed severe depression of consciousness and seizures without apparent cause.	Mannose	48-55	mannose phosphate isomerase	Homo sapiens	25-28
21240668-10	2010	We caution that, in patients with MPI-CDG, life-threatening central nervous system disturbances may occur with intravenous mannose treatment.	Mannose	123-130	mannose phosphate isomerase	Homo sapiens	34-37
21092225-6	2010	RESULTS: SP-A aggregation was dependent on its concentration, the presence of calcium, and was dose-dependently inhibited by mannose.	Mannose	125-132	surfactant protein A1	Homo sapiens	9-13
20952075-5	2010	Functional activity of the complex of mannose-binding lectin and mannose-binding lectin-associated serine protease 2 (MBL-MASP2 complex) was determined by ELISA.	Mannose	38-45	mannose-binding lectin family member 3, pseudogene	Homo sapiens	118-121
20952075-5	2010	Functional activity of the complex of mannose-binding lectin and mannose-binding lectin-associated serine protease 2 (MBL-MASP2 complex) was determined by ELISA.	Mannose	38-45	MBL associated serine protease 2	Homo sapiens	122-127
20952075-5	2010	Functional activity of the complex of mannose-binding lectin and mannose-binding lectin-associated serine protease 2 (MBL-MASP2 complex) was determined by ELISA.	Mannose	65-72	mannose-binding lectin family member 3, pseudogene	Homo sapiens	118-121
20952075-5	2010	Functional activity of the complex of mannose-binding lectin and mannose-binding lectin-associated serine protease 2 (MBL-MASP2 complex) was determined by ELISA.	Mannose	65-72	MBL associated serine protease 2	Homo sapiens	122-127
20956340-8	2010	CL-11 lectin activity was demonstrated by ELISA and showed that CL-11 has preference for l-fucose and d-mannose.	Mannose	102-111	collectin subfamily member 11	Homo sapiens	0-5
20956340-8	2010	CL-11 lectin activity was demonstrated by ELISA and showed that CL-11 has preference for l-fucose and d-mannose.	Mannose	102-111	collectin subfamily member 11	Homo sapiens	64-69
20728940-1	2010	Previous work from our laboratories has demonstrated that purified, recombinant human astrovirus coat protein (HAstV CP) binds C1q and mannose-binding lectin (MBL) inhibiting activation of the classical and lectin pathways of complement, respectively.	Mannose	135-142	mannose binding lectin 2	Homo sapiens	159-162
20705112-1	2010	Mannan (or mannose)-binding lectin (MBL) can bind to monocytes and dendritic cells, but the significance of such interactions is unknown.	Mannose	11-18	mannose binding lectin 2	Homo sapiens	36-39
20798166-10	2010	The recombinant alpha-mannosidase, like the native enzyme, could cleave alpha1-2, 1-3 and 1-6 mannosidic linkage from both high-mannose and truncated complex-type N-glycans.	Mannose	128-135	alpha-mannosidase	Solanum lycopersicum	16-33
20932025-2	2010	In this report we aimed to investigate the potential of mannose-containing glycopolymers to interact with human DC-SIGN and the ability of these glycopolymers to inhibit the interactions between DC-SIGN and the HIV envelope glycoprotein gp120.	Mannose	56-63	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	237-242
20682699-0	2010	Mannan-binding lectin deficiency results in unusual antibody production and excessive experimental colitis in response to mannose-expressing mild gut pathogens.	Mannose	122-129	mannose-binding lectin (protein C) 2	Mus musculus	0-21
20851102-0	2010	2-deoxyglucose sensitizes melanoma cells to TRAIL-induced apoptosis which is reduced by mannose.	Mannose	88-95	TNF superfamily member 10	Homo sapiens	44-49
20825246-5	2010	We mapped the glycosylation sites and calculated the glycosylation occupancy of gp120-OD8; 11 sites from 15 glycosylation motifs were determined as having high-mannose or hybrid glycosylation structures.	Mannose	160-167	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	80-85
20851102-7	2010	Mannose pre-treatment reduced enhanced killing by combination treatments, accompanied by reduced DR5 levels.	Mannose	0-7	TNF receptor superfamily member 10b	Homo sapiens	97-100
20621206-4	2010	MPO has 5 N-linked glycosylation sites, occupied by both high mannose and complex glycan structures.	Mannose	62-69	myeloperoxidase	Homo sapiens	0-3
20639197-8	2010	In addition to functional heterogeneity, endo-beta-N-acetylglucosaminidase H digestion and glycomic profiling revealed that surface beta2 subunit N-glycans at Asn-173 were high mannose forms that were different from those of Asn-32 and N104.	Mannose	177-184	neuronal differentiation 1	Homo sapiens	132-137
20477988-7	2010	In the living cell, VIP36 bound exclusively to the high-mannose form of alpha1-AT.	Mannose	56-63	lectin, mannose binding 2	Homo sapiens	20-25
20542090-10	2010	CONCLUSIONS: The high-mannose-type N-glycan attached in yeast blocks the taste-modifying activity of rMCL.	Mannose	22-29	C-type lectin domain family 4, member D	Rattus norvegicus	101-105
20709295-7	2010	Our studies show that MBL recognizes terminal mannose-containing carbohydrates on flaviviruses, resulting in neutralization and efficient clearance in vivo.	Mannose	46-53	mannose binding lectin 2	Homo sapiens	22-25
20516066-3	2010	Mannose-binding lectin (MBL) and L-ficolin (L-FCN) were selected because they function as opsonins and activate complement.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
20363321-5	2010	Upon DC-SIGN engagement by mannose- or fucose-containing oligosaccharides, the latter leads to a tailored Toll-like receptor signalling, resulting in an altered DC-cytokine profile and skewing of Th1/Th2 responses.	Mannose	27-34	CD209 molecule	Homo sapiens	5-12
20363321-5	2010	Upon DC-SIGN engagement by mannose- or fucose-containing oligosaccharides, the latter leads to a tailored Toll-like receptor signalling, resulting in an altered DC-cytokine profile and skewing of Th1/Th2 responses.	Mannose	27-34	negative elongation factor complex member C/D	Homo sapiens	196-199
20526045-3	2010	Bovine SP-D was purified from BALF using a mannose-Shepharose 6B column.	Mannose	43-50	pulmonary surfactant-associated protein D	Bos taurus	7-11
20605432-1	2010	ArtinM is a D-mannose binding lectin that has been arousing increasing interest because of its biomedical properties, especially those involving the stimulation of Th1 immune response, which confers protection against intracellular pathogens.	Mannose	12-21	negative elongation factor complex member C/D	Homo sapiens	164-167
20805325-7	2010	Importantly, the formation of high mannose N-glycans resulting from inhibition of GlcNAcT-I by GnT1IP markedly increases the adhesion of CHO cells to TM4 Sertoli cells.	Mannose	35-42	MGAT4 family, member C	Mus musculus	95-101
20592033-1	2010	Innate immunity is the first line of host defense against invading pathogens, and it is recognized by a variety of pattern recognition molecules, including mannose-binding lectin (MBL).	Mannose	156-163	mannose binding lectin 2	Homo sapiens	180-183
20592033-2	2010	MBL binds to mannose and N-acetylglucosamine residues present on the glycopolymers of microorganisms.	Mannose	13-20	mannose binding lectin 2	Homo sapiens	0-3
20681675-6	2010	The activity of this purified beta-glucosidase was completely inhibited by 1 mM Hg(2+) or 10 mM Al(3+) ion, and glucose and mannose also affected the activity.	Mannose	124-131	LOC547491	Glycine max	30-46
20511219-7	2010	Interestingly, ER-mannosidase Mns1 was not involved in RTA degradation, but it was dependent on Htm1 (ERAD-related alpha-mannosidase in yeast) and Yos9 (a putative degradation lectin), indicating that mannose trimming by Mns1 is not essential for efficient ERAD of RTA/RTL.	Mannose	201-208	mannosyl-oligosaccharide 1,2-alpha-mannosidase	Saccharomyces cerevisiae S288C	30-34
20712490-4	2010	In our study we investigated the association of single nucleotide polymorphisms (SNPs) in the first exon and promoter region of the mannose-binding lectin gene 2 (MBL2) situated on chromosome 10, with susceptibility to HBV infection.	Mannose	132-139	mannose binding lectin 2	Homo sapiens	163-167
20477988-7	2010	In the living cell, VIP36 bound exclusively to the high-mannose form of alpha1-AT.	Mannose	56-63	serpin family A member 1	Homo sapiens	72-81
20575108-0	2010	Application of champedak mannose-binding lectin in the glycoproteomic profiling of serum samples unmasks reduced expression of alpha-2 macroglobulin and complement factor B in patients with nasopharyngeal carcinoma.	Mannose	25-32	complement factor B	Homo sapiens	153-172
20554962-3	2010	In this study, we show that virulent M. tuberculosis and its cell wall mannose-capped lipoarabinomannan induce PPARgamma expression through a macrophage mannose receptor-dependent pathway.	Mannose	71-78	peroxisome proliferator activated receptor gamma	Homo sapiens	111-120
20615935-3	2010	The CI-MPR recognizes lysosomal enzymes bearing the Man-6-P modification, which arises by the addition of GlcNAc-1-phosphate to mannose residues and subsequent removal of GlcNAc by the uncovering enzyme (UCE).	Mannose	128-135	insulin like growth factor 2 receptor	Homo sapiens	4-10
20615935-3	2010	The CI-MPR recognizes lysosomal enzymes bearing the Man-6-P modification, which arises by the addition of GlcNAc-1-phosphate to mannose residues and subsequent removal of GlcNAc by the uncovering enzyme (UCE).	Mannose	128-135	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	Homo sapiens	204-207
20443635-6	2010	gp130, and a family of 14 related predicted glycoproteins whose polypeptide sequences are rapidly diverging in the Dictyostelium lineage, may contribute a functionally important shroud of high-mannose N-glycans at the interface of the amoebae with each other, their predators and prey, and the soil environment.	Mannose	193-200	Neutrophil migration (granulocyte glycoprotein)	Homo sapiens	0-5
20453072-4	2010	Glucokinase efficiently activates glucose and mannose but activates fructose only to a minor extent.	Mannose	46-53	glucokinase	Homo sapiens	0-11
20453072-5	2010	Hexokinase showed a high efficiency for fructose activation but also activated glucose and mannose.	Mannose	91-98	hexokinase 1	Homo sapiens	0-10
20714287-4	2010	It was found that polysaccharide P32 consisted of rhamnose, arabinose, xylose, mannose, glucose and galactose in a molar ratio of 3.46:49.32:58.91:0.43:2.64: 3.11, respectively.	Mannose	79-86	tubulin polyglutamylase complex subunit 1	Mus musculus	33-36
20575108-0	2010	Application of champedak mannose-binding lectin in the glycoproteomic profiling of serum samples unmasks reduced expression of alpha-2 macroglobulin and complement factor B in patients with nasopharyngeal carcinoma.	Mannose	25-32	alpha-2-macroglobulin	Homo sapiens	127-148
20575108-2	2010	Reduced expression of alpha-2 macroglobulin (AMG) and complement factor B (CFB) was detected in sera of patients with nasopharyngeal carcinoma (NPC) when pooled serum samples of the patients and those of healthy individuals were subjected to affinity isolation using immobilized champedak mannose-binding lectin and analyzed by 2-DE and densitometry.	Mannose	289-296	alpha-2-macroglobulin	Homo sapiens	22-43
20575108-2	2010	Reduced expression of alpha-2 macroglobulin (AMG) and complement factor B (CFB) was detected in sera of patients with nasopharyngeal carcinoma (NPC) when pooled serum samples of the patients and those of healthy individuals were subjected to affinity isolation using immobilized champedak mannose-binding lectin and analyzed by 2-DE and densitometry.	Mannose	289-296	alpha-2-macroglobulin	Homo sapiens	45-48
20575108-2	2010	Reduced expression of alpha-2 macroglobulin (AMG) and complement factor B (CFB) was detected in sera of patients with nasopharyngeal carcinoma (NPC) when pooled serum samples of the patients and those of healthy individuals were subjected to affinity isolation using immobilized champedak mannose-binding lectin and analyzed by 2-DE and densitometry.	Mannose	289-296	complement factor B	Homo sapiens	54-73
20575108-2	2010	Reduced expression of alpha-2 macroglobulin (AMG) and complement factor B (CFB) was detected in sera of patients with nasopharyngeal carcinoma (NPC) when pooled serum samples of the patients and those of healthy individuals were subjected to affinity isolation using immobilized champedak mannose-binding lectin and analyzed by 2-DE and densitometry.	Mannose	289-296	complement factor B	Homo sapiens	75-78
20068595-1	2010	Variants in mannose-binding lectin (MBL2; protein MBL) have shown association with different aspects (eg, lung function, infection, survival) of cystic fibrosis (CF) in some studies but not others.	Mannose	12-19	mannose binding lectin 2	Homo sapiens	36-40
20828009-8	2010	Monosaccharide analysis by GC-MS revealed that TPS1 and TPS2 were composed of arabinose, galactose, glucose, rhamnose, xylose and mannose with molar ratios of 24.2 : 23.6 : 5.9 : 3.2 : 1.8 : 1.1 and 19.3 : 26.9 : 3.2 : 2.7 : 1.3 : 5.5, respectively.	Mannose	130-137	alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1	Saccharomyces cerevisiae S288C	47-51
20828009-8	2010	Monosaccharide analysis by GC-MS revealed that TPS1 and TPS2 were composed of arabinose, galactose, glucose, rhamnose, xylose and mannose with molar ratios of 24.2 : 23.6 : 5.9 : 3.2 : 1.8 : 1.1 and 19.3 : 26.9 : 3.2 : 2.7 : 1.3 : 5.5, respectively.	Mannose	130-137	trehalose-phosphatase TPS2	Saccharomyces cerevisiae S288C	56-60
20450150-1	2010	The unbinding process of three monosaccharides--galactose, glucose, and mannose--from human surfactant protein D (hSP-D) was investigated by the molecular docking and molecular dynamics methods to explore the cause of different dynamic interaction between these monosaccharides and the protein.	Mannose	72-79	surfactant protein D	Homo sapiens	92-112
20450150-1	2010	The unbinding process of three monosaccharides--galactose, glucose, and mannose--from human surfactant protein D (hSP-D) was investigated by the molecular docking and molecular dynamics methods to explore the cause of different dynamic interaction between these monosaccharides and the protein.	Mannose	72-79	surfactant protein D	Homo sapiens	114-119
20450150-4	2010	Glucose and mannose have similar binding conformations with hSP-D.	Mannose	12-19	surfactant protein D	Homo sapiens	60-65
20118070-8	2010	Moreover, recent studies have identified the N-glycan species with which both yeast Yos9p and mammalian OS-9 associate as M7A, a Man(7)GlcNAc(2) isomer that lacks the alpha1,2-linked terminal mannose from both the B and C branches.	Mannose	192-199	Yos9p	Saccharomyces cerevisiae S288C	84-89
20118070-8	2010	Moreover, recent studies have identified the N-glycan species with which both yeast Yos9p and mammalian OS-9 associate as M7A, a Man(7)GlcNAc(2) isomer that lacks the alpha1,2-linked terminal mannose from both the B and C branches.	Mannose	192-199	OS9 endoplasmic reticulum lectin	Homo sapiens	104-108
20589530-2	2010	To understand the mechanism of activation of PEMs by OMLs, in the present study we investigated the role of a mannose-binding C-type lectin receptor, SIGNR1, in production of proinflammatory cytokines by PEMs, in which SIGNR1 acts as a physiological receptor for OMLs.	Mannose	110-117	CD209b antigen	Mus musculus	150-156
20591072-7	2010	These findings indicate differences in the recognition of glycan structures of mannan and IAV by the NCRD and emphasize the importance of the flanking sequences in determining the differing interactions of human SP-D and bovine serum collectins with mannose-rich glycoconjugates on IAV and other pathogens.	Mannose	250-257	surfactant protein D	Homo sapiens	212-216
20307522-7	2010	In non-surviving cancer patients the concentration of IGFBP-3 was significantly reduced and these molecules contained a greater amount of biantennary complex type N-glycans having more mannose, fucose, bisecting GlcNAc and terminal sialic acid residues.	Mannose	185-192	insulin like growth factor binding protein 3	Homo sapiens	54-61
20068595-1	2010	Variants in mannose-binding lectin (MBL2; protein MBL) have shown association with different aspects (eg, lung function, infection, survival) of cystic fibrosis (CF) in some studies but not others.	Mannose	12-19	mannose binding lectin 2	Homo sapiens	36-39
20523973-1	2010	Oral mannose therapy is used to treat congenital disorders of glycosylation caused by a deficiency in phosphomannose isomerase.	Mannose	5-12	mannose phosphate isomerase	Rattus norvegicus	102-126
20036592-4	2010	The enzyme is largely mannose 6-phosphorylated as assessed by mannose 6-phosphate receptor binding (80% bound) and taken up rapidly by immortalized patient lymphoblasts, where clearance of PPT substrates was demonstrated (EC(50) of 0.25 nM after overnight incubation).	Mannose	22-29	palmitoyl-protein thioesterase 1	Homo sapiens	189-192
20228837-0	2010	Inhibition of EGFR pathway signaling and the metastatic potential of breast cancer cells by PA-MSHA mediated by type 1 fimbriae via a mannose-dependent manner.	Mannose	134-141	epidermal growth factor receptor	Mus musculus	14-18
20228837-5	2010	The addition of mannose partially inhibited the PA-MSHA-stimulated cell anti-proliferative effect, cell apoptosis, cell cycle arrest, activation of apoptosis-associated caspases, and even downregulation of the EGFR signaling pathway.	Mannose	16-23	epidermal growth factor receptor	Mus musculus	210-214
20228837-8	2010	In conclusion, this study showed that the involvement of the mannose-mediated EGFR pathway has a critical function in the preclinical rationale for the development of PA-MSHA for the treatment of human breast cancer.	Mannose	61-68	epidermal growth factor receptor	Homo sapiens	78-82
20503257-7	2010	Competition experiments indicated that MBL had a similar affinity for mannose, fructose and fructoselysine.	Mannose	70-77	mannose-binding lectin family member 3, pseudogene	Homo sapiens	39-42
20065073-4	2010	We recently reported that overexpression of EDEM3 enhances glycoprotein ERAD with a concomitant increase in mannose-trimming activity in vivo.	Mannose	108-115	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	44-49
20065073-10	2010	Based on this observation, we conclude that EDEM1 activity trims mannose from the C branch of N-glycans in vivo.	Mannose	65-72	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	44-49
20306342-5	2010	Interestingly, the lectin showed high affinity for glycans which are part of ovarian cancer marker CA125, a high molecular weight mucin containing high mannose and complex bisecting type N-linked glycans as well core 1 and 2 type O-glycans.	Mannose	152-159	LOC100508689	Homo sapiens	130-135
20369831-6	2010	Moreover, with the use of preblocking procedures, the mannosyl groups and P-gp on single HeLa cell could be further detected to be (4 +/- 2) x 10(10) molecules of mannose moieties and 8.47 x 10(6) molecules of P-gp.	Mannose	163-170	ATP binding cassette subfamily B member 1	Homo sapiens	74-78
20080975-7	2010	An enzyme-linked immunosorbent assay confirmed direct binding of BanLec to gp120 and indicated that BanLec can recognize the high mannose structures that are recognized by the monoclonal antibody 2G12.	Mannose	130-137	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	75-80
19862511-2	2010	Peptide human beta-defensin 3-lysozyme showed the best bactericidal activity in vitro, but human beta-defensin 3-mannose-binding lectin showed a significant improvement in angiogenesis and tissue reconstruction.	Mannose	113-120	defensin beta 103B	Homo sapiens	97-112
19920089-6	2010	The gp120 binding activity of these immune sera was due to mannose-specific immunoglobulin, as removal of high-mannose glycans and alpha1,2-linked mannoses from gp120 abrogated serum binding.	Mannose	111-118	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	4-9
19920089-2	2010	Compared to normal mammalian glycoproteins, high-mannose-type glycans are disproportionately represented on the gp120 subunit of Env.	Mannose	49-56	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	112-117
19920089-2	2010	Compared to normal mammalian glycoproteins, high-mannose-type glycans are disproportionately represented on the gp120 subunit of Env.	Mannose	49-56	endogenous retrovirus group K member 20	Homo sapiens	129-132
19920089-6	2010	The gp120 binding activity of these immune sera was due to mannose-specific immunoglobulin, as removal of high-mannose glycans and alpha1,2-linked mannoses from gp120 abrogated serum binding.	Mannose	59-66	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	4-9
19920089-6	2010	The gp120 binding activity of these immune sera was due to mannose-specific immunoglobulin, as removal of high-mannose glycans and alpha1,2-linked mannoses from gp120 abrogated serum binding.	Mannose	59-66	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	161-166
19920089-6	2010	The gp120 binding activity of these immune sera was due to mannose-specific immunoglobulin, as removal of high-mannose glycans and alpha1,2-linked mannoses from gp120 abrogated serum binding.	Mannose	111-118	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	161-166
20460773-5	2010	The steric effect by the alpha-1,6-linked branching mannose residue to the H-1 proton chemical shift of the neighboring 3-O-substituted mannose residue was different from that of the 2-O-substituted mannose residue.	Mannose	52-59	H1.5 linker histone, cluster member	Homo sapiens	75-78
20038440-1	2010	Mannose-binding lectin (MBL) role in the carriage of oropharyngeal bacteria is not known.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
20014043-5	2010	Our study reveals that Snf3, in addition to glucose, also senses fructose and mannose, as well as the glucose analogues 2-deoxyglucose, 3-O-methylglucoside and 6-deoxyglucose.	Mannose	78-85	glucose sensor	Saccharomyces cerevisiae S288C	23-27
20014043-9	2010	Change of isoleucine-374 to valine in transmembrane segment 7 of Snf3 partially abolished sensing of fructose and mannose, while mutagenesis causing a change of phenylalanine-462 to tyrosine in transmembrane segment 10 of Snf3 abolished sensing of fructose.	Mannose	114-121	glucose sensor	Saccharomyces cerevisiae S288C	65-69
20026605-4	2010	Langerin showed outstanding affinity to galactose-6-sulfated oligosaccharides, including keratan sulfate, while it preserved binding activity to mannose, as a common feature of the C-type lectins with an EPN motif.	Mannose	145-152	CD207 molecule	Homo sapiens	0-8
20201808-1	2010	Lysosomal enzymes undergo phosphorylation on their mannose residues in the Golgi apparatus and are recognized by two distinct type I transmembrane glycoproteins designated as the mannose 6-phosphate receptors; MPR300, (Mr 300 kDa) and MPR46, (Mr 46 kDa) that internally transport them to the lysosomes.	Mannose	51-58	insulin like growth factor 2 receptor	Homo sapiens	210-216
19896672-5	2010	In addition, using LC techniques that measure total glycans released from the pure protein combined with new high resolution technologies using mass spectrometry, we have determined the locations and chain lengths of mannose residues on specific peptides derived from tryptic maps of the transferrin-exendin-4 protein.	Mannose	217-224	transferrin	Homo sapiens	288-299
20410589-3	2010	AGL-1, one of the AGLs, containing mannose at the non-reducing ends, induced CD1d-dependent IL-2 release.	Mannose	35-42	CD1d1 antigen	Mus musculus	77-81
20410589-3	2010	AGL-1, one of the AGLs, containing mannose at the non-reducing ends, induced CD1d-dependent IL-2 release.	Mannose	35-42	interleukin 2	Rattus norvegicus	92-96
20097424-3	2010	LCs express C-type lectin Langerin that has specificity for mannose, fucose and GlcNAc structures.	Mannose	60-67	CD207 molecule	Homo sapiens	26-34
20097424-8	2010	Langerin recognizes both mannose and beta-glucans present on fungal cell walls and our data demonstrate that Langerin is the major fungal pathogen receptor on human LCs that recognizes pathogenic and commensal fungi.	Mannose	25-32	CD207 molecule	Homo sapiens	0-8
20097424-8	2010	Langerin recognizes both mannose and beta-glucans present on fungal cell walls and our data demonstrate that Langerin is the major fungal pathogen receptor on human LCs that recognizes pathogenic and commensal fungi.	Mannose	25-32	CD207 molecule	Homo sapiens	109-117
20063339-0	2010	Photoassisted synthesis of luminescent mannose-Au nanodots for the detection of thyroglobulin in serum.	Mannose	39-46	thyroglobulin	Homo sapiens	80-93
20063339-1	2010	We have employed mannose-modified gold nanodots (Man-Au NDs) as a luminescence sensor for the detection of the thyroid-cancer marker thyroglobulin (Tg) in homogeneous solutions.	Mannose	17-24	thyroglobulin	Homo sapiens	133-146
20460773-5	2010	The steric effect by the alpha-1,6-linked branching mannose residue to the H-1 proton chemical shift of the neighboring 3-O-substituted mannose residue was different from that of the 2-O-substituted mannose residue.	Mannose	136-143	H1.5 linker histone, cluster member	Homo sapiens	75-78
20460773-5	2010	The steric effect by the alpha-1,6-linked branching mannose residue to the H-1 proton chemical shift of the neighboring 3-O-substituted mannose residue was different from that of the 2-O-substituted mannose residue.	Mannose	136-143	H1.5 linker histone, cluster member	Homo sapiens	75-78
23082493-2	2010	Previous studies indicated that mannose binding lectin (MBL) may modify the development of atherosclerosis.	Mannose	32-39	mannose binding lectin 2	Homo sapiens	56-59
19890709-4	2010	Inactivation of MPR300 resulted in the secretion of large amounts of newly synthesized hydrolases into the medium and also inhibited the endocytosis of mannose 6-phospharylated ligands.	Mannose	152-159	insulin like growth factor 2 receptor	Homo sapiens	16-22
19892432-2	2010	The dendritic cell-specific intercellular adhesion molecule 3 grabbing nonintegrin (DC-SIGN) is a calcium-dependent carbohydrate-binding protein with specificity for mannose-containing glycoconjugates and fucose-containing Lewis antigens.	Mannose	166-173	CD209 molecule	Homo sapiens	84-91
19892432-3	2010	Mannosylated moieties of the mycobacterial cell wall, such as mannose-capped lipoarabinomannan (manLAM) or higher-order phosphatidylinositol-mannosides (PIMs) of Mtb, were previously shown to bind to DC-SIGN on immature dendritic cells and macrophage subpopulations.	Mannose	62-69	CD209 molecule	Homo sapiens	200-207
19884343-1	2010	Alpha-mannosidosis is caused by the genetic defect of the lysosomal alpha-d-mannosidase (LAMAN), which is involved in the breakdown of free alpha-linked mannose-containing oligosaccharides originating from glycoproteins with N-linked glycans, and thus manifests itself in an extensive storage of mannose-containing oligosaccharides.	Mannose	153-160	mannosidase 2, alpha B1	Mus musculus	89-94
20816211-4	2010	Frontal affinity chromatography (FAC) and cell-surface expressed lectin assay revealed that both OS-9 and XTP3-B recognize high-mannose type N-glycans that lack the terminal mannose on the C branch.	Mannose	128-135	OS9 endoplasmic reticulum lectin	Homo sapiens	97-101
20816211-4	2010	Frontal affinity chromatography (FAC) and cell-surface expressed lectin assay revealed that both OS-9 and XTP3-B recognize high-mannose type N-glycans that lack the terminal mannose on the C branch.	Mannose	128-135	endoplasmic reticulum lectin 1	Homo sapiens	106-112
20816221-1	2010	N-acetylglucosaminyltransferase III (GnT-III) transfers N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to core mannose with a beta1,4 linkage, so-called bisecting GlcNAc, in N-glycans.	Mannose	109-116	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-35
20816221-1	2010	N-acetylglucosaminyltransferase III (GnT-III) transfers N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to core mannose with a beta1,4 linkage, so-called bisecting GlcNAc, in N-glycans.	Mannose	109-116	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	37-44
19733219-7	2009	In contrast, high-mannose-type N-glycans and Lewis X were more commonly found in rat brain ICAM-5 than in human ICAM-1 expressed in CHO cells, HEK cells, or mouse myeloma cells and ICAM-3 isolated from human T-cells.	Mannose	18-25	intercellular adhesion molecule 5	Rattus norvegicus	91-97
19958498-1	2009	BACKGROUND: Lysosomal alpha-mannosidase is an enzyme that acts to degrade N-linked oligosaccharides and hence plays an important role in mannose metabolism in humans and other mammalian species, especially livestock.	Mannose	137-144	mannosidase alpha class 2B member 1	Homo sapiens	12-39
19840833-7	2009	The interactions were Ca2+-dependent and inhibited by mannose or monoclonal antibody against the carbohydrate-recognition domain of MBL.	Mannose	54-61	mannose binding lectin 2	Homo sapiens	132-135
19879650-1	2010	DC-SIGN (dendritic cell-specific ICAM-3-grabbing non-integrin) is a myeloid pathogen-attachment factor C-type lectin which recognizes mannose- and fucose-containing oligosaccharide ligands on clinically relevant pathogens.	Mannose	134-141	CD209 molecule	Homo sapiens	0-7
19879650-1	2010	DC-SIGN (dendritic cell-specific ICAM-3-grabbing non-integrin) is a myeloid pathogen-attachment factor C-type lectin which recognizes mannose- and fucose-containing oligosaccharide ligands on clinically relevant pathogens.	Mannose	134-141	CD209 molecule	Homo sapiens	9-61
19801653-1	2009	The specificity of the cation-independent and -dependent mannose 6-phosphate receptors (CI-MPR and CD-MPR) for high mannose-type N-glycans of defined structure containing zero, one, or two Man-P-GlcNAc phosphodiester or Man-6-P phosphomonoester residues was determined by analysis on a phosphorylated glycan microarray.	Mannose	57-64	insulin like growth factor 2 receptor	Homo sapiens	88-94
19801653-1	2009	The specificity of the cation-independent and -dependent mannose 6-phosphate receptors (CI-MPR and CD-MPR) for high mannose-type N-glycans of defined structure containing zero, one, or two Man-P-GlcNAc phosphodiester or Man-6-P phosphomonoester residues was determined by analysis on a phosphorylated glycan microarray.	Mannose	57-64	mannose-6-phosphate receptor, cation dependent	Homo sapiens	99-105
19733219-7	2009	In contrast, high-mannose-type N-glycans and Lewis X were more commonly found in rat brain ICAM-5 than in human ICAM-1 expressed in CHO cells, HEK cells, or mouse myeloma cells and ICAM-3 isolated from human T-cells.	Mannose	18-25	intercellular adhesion molecule 1	Homo sapiens	112-118
19715677-5	2009	Although mannose and pyruvate also increased collectrin protein expression level, neither 2-deoxyglucose, mitochondrial fuels leucine and glutamate, sulphonylurea nor Ca(2+) channel blockers, mimicked the effects of glucose.	Mannose	9-16	collectrin, amino acid transport regulator	Mus musculus	45-55
19732381-3	2009	Here we characterize a new Arabidopsis thaliana mutant lew3 (leaf wilting 3), which has a defect in an alpha-1,2-mannosyltransferase, a homolog of ALG11 in yeast, that transfers mannose to the dolichol-linked core oligosaccharide in the last two steps on the cytosolic face of the ER in N-glycan precursor synthesis.	Mannose	178-185	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	55-59
19732381-6	2009	In addition, the lew3 mutant has low levels of normal high-mannose-type glycans, but increased levels of complex-type glycans.	Mannose	59-66	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	17-21
19787799-6	2009	In addition, a Myc/6xHis-tagged recombinant form of wild-type LMAN1 could bind to D-mannose, but that of the mutant could not.	Mannose	82-91	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	15-18
19787799-6	2009	In addition, a Myc/6xHis-tagged recombinant form of wild-type LMAN1 could bind to D-mannose, but that of the mutant could not.	Mannose	82-91	lectin, mannose binding 1	Homo sapiens	62-67
19787799-7	2009	The p.Trp67Ser mutation was located in the carbohydrate recognition domain (CRD), which is thought to participate in the selective binding of LMAN1 to the D-mannose of glycoproteins as well as the EF-motif of MCFD2.	Mannose	155-164	lectin, mannose binding 1	Homo sapiens	142-147
19787799-8	2009	Taken together, it was suggested that the p.Trp67Ser mutation might affect the molecular chaperone function of LMAN1, impairing affinity for D-mannose as well as for MCFD2, which may be responsible for F5F8D in the patient.	Mannose	141-150	lectin, mannose binding 1	Homo sapiens	111-116
19787799-8	2009	Taken together, it was suggested that the p.Trp67Ser mutation might affect the molecular chaperone function of LMAN1, impairing affinity for D-mannose as well as for MCFD2, which may be responsible for F5F8D in the patient.	Mannose	141-150	multiple coagulation factor deficiency 2, ER cargo receptor complex subunit	Homo sapiens	202-207
19467940-6	2009	RESULTS: HYPD mannose binding lectin haplotype was significantly (p<0.05) more frequent in cystic fibrosis patients with liver disease versus those without liver disease.	Mannose	14-21	MAGE family member A3	Homo sapiens	9-13
19734332-9	2009	A third mannose PTS operon, mpo, was not regulated by glucose or by the level of EII(t)(Man).	Mannose	8-15	myeloperoxidase	Homo sapiens	28-31
19467940-9	2009	CONCLUSIONS: The HYPD mannose binding lectin haplotype may predispose a subgroup of cystic fibrosis patients to a more severe liver involvement impairing the local defence mechanisms whereas the c.834-66G>T adenosine triphospate-binding cassette subfamily B member 4 variant may enhance the activity of the protein and thus exert a protective effect toward liver disease.	Mannose	22-29	MAGE family member A3	Homo sapiens	17-21
19692571-3	2009	Panx2 strongly interacts with the core and high-mannose species of Panx1 but not with Panx3.	Mannose	48-55	pannexin 2	Homo sapiens	0-5
19547928-0	2009	Relationship between tissue plasminogen activator production and specific growth rate in Chinese hamster ovary cells cultured in mannose at low temperature.	Mannose	129-136	chromosome 20 open reading frame 181	Homo sapiens	21-49
19547928-2	2009	Regardless of the temperature or mannose concentration used, an inverse relationship between the specific growth rate and tPA specific production rate was observed, suggesting that tPA production rate would be directly controlled by the growth rate.	Mannose	33-40	chromosome 20 open reading frame 181	Homo sapiens	122-125
19547928-2	2009	Regardless of the temperature or mannose concentration used, an inverse relationship between the specific growth rate and tPA specific production rate was observed, suggesting that tPA production rate would be directly controlled by the growth rate.	Mannose	33-40	chromosome 20 open reading frame 181	Homo sapiens	181-184
19052865-5	2009	We hypothesize that apoptosis induced by treatment of Hep G2 and BEL-7402 cells with PA-MSHA is mediated by the mannose residues of PA-MSHA and is propagated through the extrinsic apoptosis pathway directly through caspase-8.	Mannose	112-119	caspase 8	Homo sapiens	215-224
19625484-6	2009	Here, we demonstrate that human GIIbeta-MRH binds to high-mannose-type glycans.	Mannose	58-65	protein kinase C substrate 80K-H	Homo sapiens	32-39
19625484-9	2009	Our results clearly demonstrate the capacity of the GIIbeta-MRH to bind high-mannose-type glycans and its importance in efficient glucose trimming of N-glycans.	Mannose	77-84	protein kinase C substrate 80K-H	Homo sapiens	52-59
19671700-5	2009	Analysis of tryptic fragments of recombinant human punctin-1 by mass spectrometry identified a peptide derived from TSR1 containing the (36)WDAWGPWSECSRTC(49) sequence of interest modified with two mannose residues and a Glc-Fuc disaccharide (O-fucosylation).	Mannose	198-205	ADAMTS like 1	Homo sapiens	51-60
19671700-5	2009	Analysis of tryptic fragments of recombinant human punctin-1 by mass spectrometry identified a peptide derived from TSR1 containing the (36)WDAWGPWSECSRTC(49) sequence of interest modified with two mannose residues and a Glc-Fuc disaccharide (O-fucosylation).	Mannose	198-205	TSR1 ribosome maturation factor	Homo sapiens	116-120
19692571-3	2009	Panx2 strongly interacts with the core and high-mannose species of Panx1 but not with Panx3.	Mannose	48-55	pannexin 1	Homo sapiens	67-72
19692571-5	2009	Interestingly, Panx2, which is also a glycoprotein and seems to only be glycosylated to a high-mannose form, is more abundant in intracellular compartments, except when coexpressed with Panx1, when its cell surface distribution increases by twofold.	Mannose	95-102	pannexin 2	Homo sapiens	15-20
19718030-4	2009	Mannose-expressing Mycobacterium tuberculosis and human immunodeficiency virus type 1 (HIV-1) induced the recruitment of effector proteins to the DC-SIGN signalosome to activate Raf-1, whereas fucose-expressing pathogens such as Helicobacter pylori actively dissociated the KSR1-CNK-Raf-1 complex from the DC-SIGN signalosome.	Mannose	0-7	CD209 molecule	Homo sapiens	146-153
19718030-4	2009	Mannose-expressing Mycobacterium tuberculosis and human immunodeficiency virus type 1 (HIV-1) induced the recruitment of effector proteins to the DC-SIGN signalosome to activate Raf-1, whereas fucose-expressing pathogens such as Helicobacter pylori actively dissociated the KSR1-CNK-Raf-1 complex from the DC-SIGN signalosome.	Mannose	0-7	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	178-183
19718030-4	2009	Mannose-expressing Mycobacterium tuberculosis and human immunodeficiency virus type 1 (HIV-1) induced the recruitment of effector proteins to the DC-SIGN signalosome to activate Raf-1, whereas fucose-expressing pathogens such as Helicobacter pylori actively dissociated the KSR1-CNK-Raf-1 complex from the DC-SIGN signalosome.	Mannose	0-7	kinase suppressor of ras 1	Homo sapiens	274-278
19718030-4	2009	Mannose-expressing Mycobacterium tuberculosis and human immunodeficiency virus type 1 (HIV-1) induced the recruitment of effector proteins to the DC-SIGN signalosome to activate Raf-1, whereas fucose-expressing pathogens such as Helicobacter pylori actively dissociated the KSR1-CNK-Raf-1 complex from the DC-SIGN signalosome.	Mannose	0-7	connector enhancer of kinase suppressor of Ras 1	Homo sapiens	279-282
19718030-4	2009	Mannose-expressing Mycobacterium tuberculosis and human immunodeficiency virus type 1 (HIV-1) induced the recruitment of effector proteins to the DC-SIGN signalosome to activate Raf-1, whereas fucose-expressing pathogens such as Helicobacter pylori actively dissociated the KSR1-CNK-Raf-1 complex from the DC-SIGN signalosome.	Mannose	0-7	Raf-1 proto-oncogene, serine/threonine kinase	Homo sapiens	283-288
19718030-4	2009	Mannose-expressing Mycobacterium tuberculosis and human immunodeficiency virus type 1 (HIV-1) induced the recruitment of effector proteins to the DC-SIGN signalosome to activate Raf-1, whereas fucose-expressing pathogens such as Helicobacter pylori actively dissociated the KSR1-CNK-Raf-1 complex from the DC-SIGN signalosome.	Mannose	0-7	CD209 molecule	Homo sapiens	306-313
19880800-1	2009	In Saccharomyces cerevisiae, the PMT, KRE2/MNT1, and MNN1 mannosyltransferase protein families catalyze the steps of the O-mannosylation pathway, sequentially adding mannoses to target proteins.	Mannose	166-174	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	38-42
19880800-1	2009	In Saccharomyces cerevisiae, the PMT, KRE2/MNT1, and MNN1 mannosyltransferase protein families catalyze the steps of the O-mannosylation pathway, sequentially adding mannoses to target proteins.	Mannose	166-174	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	43-47
19574302-2	2009	The reaction catalysed by PMI is the first committed step in the synthesis of mannose-containing sugar chains and provides a link between glucose metabolism and mannosylation.	Mannose	78-85	mannose phosphate isomerase	Homo sapiens	26-29
19880800-1	2009	In Saccharomyces cerevisiae, the PMT, KRE2/MNT1, and MNN1 mannosyltransferase protein families catalyze the steps of the O-mannosylation pathway, sequentially adding mannoses to target proteins.	Mannose	166-174	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	53-57
19681073-1	2009	The HIV envelope glycoprotein gp120 takes advantage of the high-mannose clusters on its surface to target the C-type lectin dendritic cell-specific intracellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) on dendritic cells.	Mannose	64-71	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	30-35
19699205-8	2009	Mannose and N-acetylgalactosamine inhibited binding of MBL and L-ficolin to GN5-DPPE, respectively.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	55-58
19699205-8	2009	Mannose and N-acetylgalactosamine inhibited binding of MBL and L-ficolin to GN5-DPPE, respectively.	Mannose	0-7	ficolin 2	Homo sapiens	63-72
19722841-3	2009	DC-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is a pattern recognition receptor with a broad pathogen recognition specificity as a result of its affinity for mannose and fucose carbohydrates.	Mannose	189-196	CD209 molecule	Homo sapiens	0-66
19689135-7	2009	Well-defined recognition systems, namely, mannose derivatives (Man1, Man4, and Man9) with a mannose binding lectin (Concanavalin A) and a stage-specific embryonic antigens-3 (SSEA-3) with a monoclonal antibody (anti-SSEA-3) were chosen to establish this detection tool.	Mannose	42-49	LEM domain containing 3	Homo sapiens	63-67
19689135-7	2009	Well-defined recognition systems, namely, mannose derivatives (Man1, Man4, and Man9) with a mannose binding lectin (Concanavalin A) and a stage-specific embryonic antigens-3 (SSEA-3) with a monoclonal antibody (anti-SSEA-3) were chosen to establish this detection tool.	Mannose	42-49	mannosidase alpha class 1A member 1	Homo sapiens	79-83
19689135-7	2009	Well-defined recognition systems, namely, mannose derivatives (Man1, Man4, and Man9) with a mannose binding lectin (Concanavalin A) and a stage-specific embryonic antigens-3 (SSEA-3) with a monoclonal antibody (anti-SSEA-3) were chosen to establish this detection tool.	Mannose	92-99	LEM domain containing 3	Homo sapiens	63-67
19689135-7	2009	Well-defined recognition systems, namely, mannose derivatives (Man1, Man4, and Man9) with a mannose binding lectin (Concanavalin A) and a stage-specific embryonic antigens-3 (SSEA-3) with a monoclonal antibody (anti-SSEA-3) were chosen to establish this detection tool.	Mannose	92-99	mannosidase alpha class 1A member 1	Homo sapiens	79-83
19487139-8	2009	HFE:CI-MPR binding was mediated through phosphorylated mannose residues on HFE.	Mannose	55-62	homeostatic iron regulator	Homo sapiens	0-3
19487139-8	2009	HFE:CI-MPR binding was mediated through phosphorylated mannose residues on HFE.	Mannose	55-62	insulin like growth factor 2 receptor	Homo sapiens	4-10
19487139-8	2009	HFE:CI-MPR binding was mediated through phosphorylated mannose residues on HFE.	Mannose	55-62	homeostatic iron regulator	Homo sapiens	75-78
19778448-6	2009	Cells transfected with GPC retained surface membrane-associated expression of GP1 as determined by immunofluorescence assay, in addition to secreting the glycoprotein.Secreted GP1 derived from GPC expression has a higher content of high mannose N-linked glycosylation than sGP1 expressed independently from the GP2 portion of the protein.	Mannose	237-244	glycophorin C (Gerbich blood group)	Homo sapiens	23-26
19778448-6	2009	Cells transfected with GPC retained surface membrane-associated expression of GP1 as determined by immunofluorescence assay, in addition to secreting the glycoprotein.Secreted GP1 derived from GPC expression has a higher content of high mannose N-linked glycosylation than sGP1 expressed independently from the GP2 portion of the protein.	Mannose	237-244	GTP binding protein 1	Homo sapiens	176-179
19778448-6	2009	Cells transfected with GPC retained surface membrane-associated expression of GP1 as determined by immunofluorescence assay, in addition to secreting the glycoprotein.Secreted GP1 derived from GPC expression has a higher content of high mannose N-linked glycosylation than sGP1 expressed independently from the GP2 portion of the protein.	Mannose	237-244	glycophorin C (Gerbich blood group)	Homo sapiens	193-196
19722841-3	2009	DC-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is a pattern recognition receptor with a broad pathogen recognition specificity as a result of its affinity for mannose and fucose carbohydrates.	Mannose	189-196	CD209 molecule	Homo sapiens	68-75
19384925-2	2009	In this study, a series of sugars, including sucrose, lactose, trehalose, maltose, fructose, galactose, fucose, mannose, and glucose were studied by modulated DSC and freeze-dry microscopy in order to better understand whether sucrose is unique in any way with respect to this behavior, as well as to explore the physical basis, and the pharmaceutical significance of these multiple transitions.	Mannose	112-119	desmocollin 3	Homo sapiens	159-162
19556306-7	2009	alpha-Mannosidase II inhibitor blocked the processing N-glycans to complex type, but TLR4 with high mannose type appeared on the cell surface, suggesting that TLR4 is destined to locate on the cell surface before processing N-glycans from a high mannose type to a complex type.	Mannose	100-107	toll like receptor 4	Homo sapiens	85-89
19621913-2	2009	This synthetic strategy relies on the ability of mannose-derived nitrone to undergo a highly stereoselective nucleophilic addition of various Grignard reagents to access syn orientation of alkenes, which then smoothly undergo ring-closing metathesis (RCM) to provide this framework.	Mannose	49-56	synemin	Homo sapiens	5-8
19414060-2	2009	METHODS: In the present study, Polygonatum odoratum lectin (designated POL), a mannose-binding specific GNA-related lectin, possessed a remarkable antiproliferative activity toward murine fibrosarcoma L929 cells.	Mannose	79-86	predicted gene, 42368	Mus musculus	71-74
19556306-3	2009	Lectin blot and cell surface biotinylation revealed that TLR4 exhibited the 110 kDa protein with high mannose type N-glycans and the 130 kDa protein with complex type N-glycans and that only the 130 kDa TLR4 with complex type N-glycans was expressed on the cell surface.	Mannose	102-109	toll like receptor 4	Homo sapiens	57-61
19556306-7	2009	alpha-Mannosidase II inhibitor blocked the processing N-glycans to complex type, but TLR4 with high mannose type appeared on the cell surface, suggesting that TLR4 is destined to locate on the cell surface before processing N-glycans from a high mannose type to a complex type.	Mannose	100-107	toll like receptor 4	Homo sapiens	159-163
19556306-4	2009	The cells transfected with a mutant TLR4(C88A) alone expressed only the 110 kDa TLR4 with a high mannose type N-glycan, which did not appear on the cell surface.	Mannose	97-104	toll like receptor 4	Homo sapiens	36-40
19556306-7	2009	alpha-Mannosidase II inhibitor blocked the processing N-glycans to complex type, but TLR4 with high mannose type appeared on the cell surface, suggesting that TLR4 is destined to locate on the cell surface before processing N-glycans from a high mannose type to a complex type.	Mannose	246-253	toll like receptor 4	Homo sapiens	159-163
19556306-4	2009	The cells transfected with a mutant TLR4(C88A) alone expressed only the 110 kDa TLR4 with a high mannose type N-glycan, which did not appear on the cell surface.	Mannose	97-104	toll like receptor 4	Homo sapiens	80-84
19626429-8	2009	Molecular modelling of the jacalin domain and mannose docking confirmed that Ver2 possesses D: -mannose binding capacity.	Mannose	46-53	ver2	Triticum aestivum	77-81
19626429-8	2009	Molecular modelling of the jacalin domain and mannose docking confirmed that Ver2 possesses D: -mannose binding capacity.	Mannose	96-103	ver2	Triticum aestivum	77-81
19275921-5	2009	Therefore we propose that MBL2 polymorphisms responsible for defective production of mannose binding lectin (MBL) protein play a role in the increased susceptibility to high-risk HPV infection but not to cervical cancer onset and development.	Mannose	85-92	mannose binding lectin 2	Homo sapiens	26-30
19538011-4	2009	The mean size of PAM-ACV-lip was significantly smaller than those of conventional ACV liposomes and ManN-ACV-lip due to the more conical packing parameter of mannose-conjugated phospholipid.	Mannose	158-165	peptidylglycine alpha-amidating monooxygenase	Mus musculus	17-20
19556165-2	2009	Inducible nitric oxide synthase (iNOS) and NO are upregulated in murine macrophages stimulated with interferon-gamma (IFNgamma) and mannose-capped lipoarabinomannan (ManLAM), a major lipoglycan in the cell wall of M. tuberculosis.	Mannose	132-139	nitric oxide synthase 2, inducible	Mus musculus	0-31
19556165-2	2009	Inducible nitric oxide synthase (iNOS) and NO are upregulated in murine macrophages stimulated with interferon-gamma (IFNgamma) and mannose-capped lipoarabinomannan (ManLAM), a major lipoglycan in the cell wall of M. tuberculosis.	Mannose	132-139	nitric oxide synthase 2, inducible	Mus musculus	33-37
19346256-0	2009	Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans.	Mannose	104-111	OS9 endoplasmic reticulum lectin	Homo sapiens	6-10
19346256-6	2009	Using frontal affinity chromatography, we demonstrated that the recombinant hOS-9 mannose 6-phosphate receptor homology domain specifically binds N-glycans lacking the terminal mannose from the C branch in vitro.	Mannose	82-89	OS9 endoplasmic reticulum lectin	Homo sapiens	76-81
19346256-9	2009	Thus, we propose a model for mannose trimming and the requirement for hOS-9 lectin activity in glycoprotein ERAD in which N-glycans lacking the terminal mannose from the C branch are recognized by hOS-9 and targeted for degradation.	Mannose	153-160	OS9 endoplasmic reticulum lectin	Homo sapiens	70-75
19520203-0	2009	Mannose addition by yeast Pichia Pastoris on recombinant HER-2 protein inhibits recognition by the monoclonal antibody herceptin.	Mannose	0-7	glutamyl-tRNA(Gln) amidotransferase subunit HER2	Saccharomyces cerevisiae S288C	57-62
19520203-3	2009	This phenomenon is due to glycosylation via mannose of the full-length HER-2 protein that extends over the antigenic epitope, which is recognized by Herceptin.	Mannose	44-51	glutamyl-tRNA(Gln) amidotransferase subunit HER2	Saccharomyces cerevisiae S288C	71-76
19410272-0	2009	Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo.	Mannose	21-28	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	80-85
19410272-3	2009	For example, gp120 mannose residues can induce immunosuppressive responses in vitro, including IL-10 expression, via mannose C-type lectin receptors on antigen-presenting cells.	Mannose	19-26	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	13-18
19410272-3	2009	For example, gp120 mannose residues can induce immunosuppressive responses in vitro, including IL-10 expression, via mannose C-type lectin receptors on antigen-presenting cells.	Mannose	19-26	interleukin 10	Homo sapiens	95-100
19207313-10	2009	Partial normalization of ALS and IGFBP-3 glycosylation was associated with improvement in linear growth in a child with CDG-Ib during initiation of oral mannose therapy.	Mannose	153-160	insulin like growth factor binding protein 3	Homo sapiens	33-40
19395407-0	2009	AMR1, an Arabidopsis gene that coordinately and negatively regulates the mannose/l-galactose ascorbic acid biosynthetic pathway.	Mannose	73-80	ascorbic acid mannose pathway regulator 1	Arabidopsis thaliana	0-4
19195858-2	2009	Not only fructose, but also glucose, mannose, rhamnose and glucosamine could inhibit the lectin.	Mannose	37-44	lectin	Musa acuminata	89-95
19395407-3	2009	A gene that regulates the Man/l-galactose (l-Gal) AsA pathway, AMR1 (for ascorbic acid mannose pathway regulator 1), was identified in an activation-tagged Arabidopsis (Arabidopsis thaliana) ozone-sensitive mutant that had 60% less leaf AsA than wild-type plants.	Mannose	87-94	ascorbic acid mannose pathway regulator 1	Arabidopsis thaliana	63-67
19083115-11	2009	However, when glucose tolerance tests were given, a positive correlation between mannose levels and insulin levels was observed.	Mannose	81-88	insulin	Canis lupus familiaris	100-107
19083115-12	2009	Therefore, plasma mannose levels obtained via glucose tolerance testing may be used as a new diagnostic method for evaluating insulin resistance or deficiency in diabetic dogs.	Mannose	18-25	insulin	Canis lupus familiaris	126-133
19083115-8	2009	Interestingly, plasma mannose levels were affected by plasma insulin levels.	Mannose	22-29	insulin	Canis lupus familiaris	61-68
19518486-5	2009	The P-selectin/P-selectin-glycoprotein-ligand-1 (PSGL-1) bond is controlled by the interface between the epidermal growth factor (EGF) and lectin domains of P-selectin, and the type 1 fimbrial adhesive protein (FimH)/mannose bond is governed by the interface between the lectin and pilin domains of FimH.	Mannose	217-224	selectin P	Homo sapiens	4-14
19083115-9	2009	In the context of feeding and glucose tolerance tests, plasma mannose levels responded to changes in circulating insulin levels.	Mannose	62-69	insulin	Canis lupus familiaris	113-120
19264785-4	2009	2G12 binding to this protein, identified as Pst1, was enhanced by adding the Delta mnn1 deletion to the Delta pmr1 background, ensuring the exposure of terminal alpha1,2-linked mannose residues on the D1 and D3 arms of high-mannose glycans.	Mannose	177-184	Pst1p	Saccharomyces cerevisiae S288C	44-48
19264785-4	2009	2G12 binding to this protein, identified as Pst1, was enhanced by adding the Delta mnn1 deletion to the Delta pmr1 background, ensuring the exposure of terminal alpha1,2-linked mannose residues on the D1 and D3 arms of high-mannose glycans.	Mannose	224-231	Pst1p	Saccharomyces cerevisiae S288C	44-48
19518486-5	2009	The P-selectin/P-selectin-glycoprotein-ligand-1 (PSGL-1) bond is controlled by the interface between the epidermal growth factor (EGF) and lectin domains of P-selectin, and the type 1 fimbrial adhesive protein (FimH)/mannose bond is governed by the interface between the lectin and pilin domains of FimH.	Mannose	217-224	selectin P ligand	Homo sapiens	15-47
19518486-5	2009	The P-selectin/P-selectin-glycoprotein-ligand-1 (PSGL-1) bond is controlled by the interface between the epidermal growth factor (EGF) and lectin domains of P-selectin, and the type 1 fimbrial adhesive protein (FimH)/mannose bond is governed by the interface between the lectin and pilin domains of FimH.	Mannose	217-224	selectin P ligand	Homo sapiens	49-55
19518486-5	2009	The P-selectin/P-selectin-glycoprotein-ligand-1 (PSGL-1) bond is controlled by the interface between the epidermal growth factor (EGF) and lectin domains of P-selectin, and the type 1 fimbrial adhesive protein (FimH)/mannose bond is governed by the interface between the lectin and pilin domains of FimH.	Mannose	217-224	epidermal growth factor	Homo sapiens	105-134
19518486-5	2009	The P-selectin/P-selectin-glycoprotein-ligand-1 (PSGL-1) bond is controlled by the interface between the epidermal growth factor (EGF) and lectin domains of P-selectin, and the type 1 fimbrial adhesive protein (FimH)/mannose bond is governed by the interface between the lectin and pilin domains of FimH.	Mannose	217-224	selectin P	Homo sapiens	15-25
19249874-2	2009	Although SP-D shows a preference for glucose/maltose, the protein also recognizes d-mannose and a variety of mannose-rich microbial ligands.	Mannose	82-91	surfactant protein D	Homo sapiens	9-13
19264337-5	2009	Several carbohydrate-binding agents (CBAs), such as the plant lectins HHA, GNA (mannose-specific) and UDA (N-acetylglucosamine-specific), inhibited dose-dependently the binding of DENV and subsequently viral replication in Raji/DC-SIGN(+) cells (EC(50): 0.1-2.2 microM).	Mannose	80-87	CD209 molecule	Homo sapiens	228-235
19412661-12	2009	Glycoarray analysis suggested that high mannose glycan structures on fetuin A were only detectable in cancer but not normal tissue.	Mannose	40-47	alpha 2-HS glycoprotein	Homo sapiens	69-77
19249874-2	2009	Although SP-D shows a preference for glucose/maltose, the protein also recognizes d-mannose and a variety of mannose-rich microbial ligands.	Mannose	84-91	surfactant protein D	Homo sapiens	9-13
19303067-1	2009	A series of "clickable" mannopyranosides bearing a triflate leaving group at C-2 position were synthesized and tested for their potential as (18)F-labeling precursors.	Mannose	24-40	complement C2	Homo sapiens	77-80
19249874-4	2009	Trimeric neck plus carbohydrate recognition domains from human SP-D (hNCRD) preferred alpha1-2-linked dimannose (DM) over the branched trimannose (TM) core, alpha1-3 or alpha1-6 DM, or D-mannose.	Mannose	185-194	surfactant protein D	Homo sapiens	63-67
19204327-3	2009	FLT3 ITD has also been found partially retained as a high-mannose precursor in an intracellular compartment.	Mannose	58-65	fms related receptor tyrosine kinase 3	Homo sapiens	0-4
19323988-8	2009	Furthermore, Western blotting analysis showed the presence of two isoforms of the protein (70 and 140 kDa), probably corresponding to the high mannose-type SERT and its dimeric form.	Mannose	143-150	solute carrier family 6 member 4	Bos taurus	156-160
19255873-4	2009	Plasma chitotriosidase and MIP-1beta decrease upon successful enzyme replacement therapy (ERT) with mannose-terminated recombinant glucocerebrosidase (alglucerase).	Mannose	100-107	C-C motif chemokine ligand 4	Homo sapiens	27-36
19222173-6	2009	The inhibitory activities of various glycans suggest that UGGT has a strong affinity for the core pentasaccharide (Man3GlcNAc2) of high-mannose-type glycans.	Mannose	136-143	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	58-62
19183188-4	2009	LMAN1 is a mannose-specific lectin that cycles between the endoplasmic reticulum (ER) and the ER-Golgi intermediate compartment.	Mannose	11-18	lectin, mannose binding 1	Homo sapiens	0-5
19129245-1	2009	The serum mannan-binding protein (MBP) is a host defense C-type lectin specific for mannose, N-acetylglucosamine, and fucose residues, and exhibits growth inhibitory activity toward human colorectal carcinoma cells.	Mannose	84-91	myelin basic protein	Homo sapiens	10-32
19129245-1	2009	The serum mannan-binding protein (MBP) is a host defense C-type lectin specific for mannose, N-acetylglucosamine, and fucose residues, and exhibits growth inhibitory activity toward human colorectal carcinoma cells.	Mannose	84-91	myelin basic protein	Homo sapiens	34-37
19255873-4	2009	Plasma chitotriosidase and MIP-1beta decrease upon successful enzyme replacement therapy (ERT) with mannose-terminated recombinant glucocerebrosidase (alglucerase).	Mannose	100-107	glucosylceramidase beta	Homo sapiens	151-162
19255873-12	2009	In conclusion, ERT with mannose-terminated gluocerebrosidase results in prominent corrections of plasma chitotriosidase, a marker of Gaucher cells, and in particular of plasma MIP-1beta, a marker of inflammatory phagocytes.	Mannose	24-31	C-C motif chemokine ligand 4	Homo sapiens	176-185
19124464-7	2009	(iii) EGFR binding to GM3 was enhanced in glycosidase-treated cells that accumulated GlcNAc termini, whereas GM3 did not bind to EGFR from ManIB-knocked down cells that accumulated high mannose-type N-glycans.	Mannose	186-193	epidermal growth factor receptor	Homo sapiens	6-10
19157945-5	2009	In the extreme case of fibroblasts derived from Mpi null mice (&lt;0.001% MPI activity), intracellular Man-6-P levels greatly increased in response to exogenous mannose, and this produced a dose-dependent decrease in the steady state level of the major LLO precursor.	Mannose	161-168	mannose phosphate isomerase	Mus musculus	48-51
19157945-5	2009	In the extreme case of fibroblasts derived from Mpi null mice (&lt;0.001% MPI activity), intracellular Man-6-P levels greatly increased in response to exogenous mannose, and this produced a dose-dependent decrease in the steady state level of the major LLO precursor.	Mannose	161-168	mannose phosphate isomerase	Mus musculus	74-77
19277361-1	2009	Functionalisation of MSN with mannose for PDT applications dramatically improved the efficiency of PDT on breast cancer cells.	Mannose	30-37	moesin	Homo sapiens	21-24
19107881-9	2009	Furthermore, the PSM" protein is N-glycosylated by a mixture of high-mannose and complex type oligosaccharides and therefore trafficked beyond the cis-Golgi compartment.	Mannose	69-76	folate hydrolase 1	Homo sapiens	17-21
19118014-4	2009	Among 28 candidate genes, LMAN1/ERGIC53, a mannose-specific lectin mediating endoplasmatic reticulum (ER)-to-Golgi transit of glycosylated proteins, showed high mutation frequency in MSI-H colorectal cancer cell lines (52%; 12 of 23), carcinomas (45%; 72 of 161), and adenomas (40%; 8 of 20).	Mannose	43-50	lectin, mannose binding 1	Homo sapiens	26-31
19796530-1	2009	OBJECTIVE: The present study aimed to investigate the interactions among salivary S. mutans colonisation, serum mannose binding lectin level (MBL), oral ulcer activity and disease course in patients with Behcet"s disease (BD).	Mannose	112-119	mannose binding lectin 2	Homo sapiens	142-145
19211523-1	2009	This study aimed to investigate the effect of mannose-binding lectin (MBL) on infections with Escherichia coli in chickens.	Mannose	46-53	mannose binding lectin 2	Gallus gallus	70-73
19202265-2	2009	The substrate specificity of the recombinant Endo-LE was the same as that of the native enzyme, showing strong activity towards the high-mannose type N-glycans with the Manalpha1-2Manalpha1-3Manbeta1-4GlcNAcbeta1-4GlcNAc unit.	Mannose	137-144	cytosolic endo-beta-N-acetylglucosaminidase	Solanum lycopersicum	45-52
19154352-9	2009	Our data demonstrate that secreted rmDNase1 and murine parotid DNase1 are mixtures of three different di-N-glycosylated molecules containing two high-mannose, two complex N-glycans or one high-mannose and one complex N-glycan moiety.	Mannose	150-157	deoxyribonuclease I	Mus musculus	37-43
19154352-9	2009	Our data demonstrate that secreted rmDNase1 and murine parotid DNase1 are mixtures of three different di-N-glycosylated molecules containing two high-mannose, two complex N-glycans or one high-mannose and one complex N-glycan moiety.	Mannose	193-200	deoxyribonuclease I	Mus musculus	37-43
19059495-0	2009	Activation of HIV-1 Gag-specific CD8+ T cells by yeast-derived VLP-pulsed dendritic cells is influenced by the level of mannose on the VLP antigen.	Mannose	120-127	Pr55(Gag)	Human immunodeficiency virus 1	20-23
19059495-0	2009	Activation of HIV-1 Gag-specific CD8+ T cells by yeast-derived VLP-pulsed dendritic cells is influenced by the level of mannose on the VLP antigen.	Mannose	120-127	CD8a molecule	Homo sapiens	33-36
19059495-10	2009	These results indicate that lectin receptors recognizing mannose may influence the Th1/Th2 balance of the immune response, resulting in reduced efficiency of CD8(+) T cell activation by a heavily mannosylated antigen presented by DCs.	Mannose	57-64	negative elongation factor complex member C/D	Homo sapiens	83-86
19059495-10	2009	These results indicate that lectin receptors recognizing mannose may influence the Th1/Th2 balance of the immune response, resulting in reduced efficiency of CD8(+) T cell activation by a heavily mannosylated antigen presented by DCs.	Mannose	57-64	CD8a molecule	Homo sapiens	158-161
19075007-6	2009	Recombinant GLT25D1 and GLT25D2 enzymes showed a strong galactosyltransferase activity toward various types of collagen and toward the serum mannose-binding lectin MBL, which contains a collagen domain.	Mannose	141-148	collagen beta(1-O)galactosyltransferase 1	Homo sapiens	12-19
19075007-6	2009	Recombinant GLT25D1 and GLT25D2 enzymes showed a strong galactosyltransferase activity toward various types of collagen and toward the serum mannose-binding lectin MBL, which contains a collagen domain.	Mannose	141-148	collagen beta(1-O)galactosyltransferase 2	Homo sapiens	24-31
19075007-6	2009	Recombinant GLT25D1 and GLT25D2 enzymes showed a strong galactosyltransferase activity toward various types of collagen and toward the serum mannose-binding lectin MBL, which contains a collagen domain.	Mannose	141-148	mannose-binding lectin family member 3, pseudogene	Homo sapiens	164-167
18996748-1	2009	Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, selectively binds distinct chemical patterns, including carbohydrates expressed on Group B streptococcus (GBS).	Mannose	0-7	mannose-binding lectin (protein C) 2	Mus musculus	24-27
19159617-3	2009	Our results show that the pattern of E-cadherin N-glycosylation in mammary carcinoma is characterized by highly branched N-glycans, increase in sialylation and an expression of few high mannose structures.	Mannose	186-193	cadherin 1	Canis lupus familiaris	37-47
19147415-3	2009	It acts by direct binding to mannose residues that are abundantly present on the HIV gp120 envelope and so interrupts the virus entry process.	Mannose	29-36	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	85-90
19171887-7	2009	Mutation of the putative mannose-binding motif within C-type lectin domain of Mincle abrogated Malassezia recognition.	Mannose	25-32	C-type lectin domain family 4, member e	Mus musculus	78-84
18927215-4	2009	Western blot analysis of the whole membrane proteins or proteins expressed at the cell surface showed that Q489H-TSHR expressed in HEK293 transfected cells are restricted to mannose-rich uncleaved receptor.	Mannose	174-181	thyroid stimulating hormone receptor	Homo sapiens	113-117
19101978-1	2009	Mannostatin A is a potent inhibitor of the mannose-trimming enzyme, Golgi alpha-mannosidase II (GMII), which acts late in the N-glycan processing pathway.	Mannose	43-50	alpha-Mannosidase class II a	Drosophila melanogaster	68-94
19101978-1	2009	Mannostatin A is a potent inhibitor of the mannose-trimming enzyme, Golgi alpha-mannosidase II (GMII), which acts late in the N-glycan processing pathway.	Mannose	43-50	alpha-Mannosidase class II a	Drosophila melanogaster	96-100
19118014-4	2009	Among 28 candidate genes, LMAN1/ERGIC53, a mannose-specific lectin mediating endoplasmatic reticulum (ER)-to-Golgi transit of glycosylated proteins, showed high mutation frequency in MSI-H colorectal cancer cell lines (52%; 12 of 23), carcinomas (45%; 72 of 161), and adenomas (40%; 8 of 20).	Mannose	43-50	lectin, mannose binding 1	Homo sapiens	32-39
19021579-7	2008	CLRs such as DC-SIGN (DC-specific intracellular adhesion molecule-3 grabbing non-integrin) recognizes high-mannose-containing structures and Lewis antigens (Le(x), Le(y), Le(b) and Le(a)), whereas the CLR MGL (macrophage galactose/N-acetylgalactosamine-specific C-type lectin) recognizes GalNAc.	Mannose	107-114	CD209 molecule	Homo sapiens	13-20
19421409-5	2009	RESULTS: High mannose, bi and tri-antennary nonbisected and bisected complex N-glycan, N-acetyl glucosamine and galactose were expressed by drusen, retinal pigment epithelium, Bruch"s membrane, and photoreceptors while N-acetyl galactosamine and fucose were absent; treatment with neuraminidase exposed subterminal galactose in both sites and sparse N-acetyl galactosamine residues in drusen alone.	Mannose	14-21	neuraminidase 1	Homo sapiens	281-294
19279679-3	2009	Initially known as the low-affinity receptor for immunoglobulin E (Fc epsilonRII), CD23 displays various other physiologic ligands such as CD21, CD11b/c, CD47-vitronectin, and mannose-containing proteins.	Mannose	176-183	Fc epsilon receptor II	Homo sapiens	83-87
18957309-1	2009	Circulating mannan (or mannose)-binding lectin (MBL) is genetically determined.	Mannose	23-30	mannose binding lectin 2	Homo sapiens	48-51
18991397-5	2008	Excess mannose abolished the binding of SP-D to sMD-2.	Mannose	7-14	surfactant protein D	Homo sapiens	40-44
18991397-5	2008	Excess mannose abolished the binding of SP-D to sMD-2.	Mannose	7-14	small nuclear ribonucleoprotein D2 polypeptide	Homo sapiens	48-53
19021579-7	2008	CLRs such as DC-SIGN (DC-specific intracellular adhesion molecule-3 grabbing non-integrin) recognizes high-mannose-containing structures and Lewis antigens (Le(x), Le(y), Le(b) and Le(a)), whereas the CLR MGL (macrophage galactose/N-acetylgalactosamine-specific C-type lectin) recognizes GalNAc.	Mannose	107-114	CD209 molecule	Homo sapiens	22-89
19021579-7	2008	CLRs such as DC-SIGN (DC-specific intracellular adhesion molecule-3 grabbing non-integrin) recognizes high-mannose-containing structures and Lewis antigens (Le(x), Le(y), Le(b) and Le(a)), whereas the CLR MGL (macrophage galactose/N-acetylgalactosamine-specific C-type lectin) recognizes GalNAc.	Mannose	107-114	C-type lectin domain containing 10A	Homo sapiens	205-208
19021579-7	2008	CLRs such as DC-SIGN (DC-specific intracellular adhesion molecule-3 grabbing non-integrin) recognizes high-mannose-containing structures and Lewis antigens (Le(x), Le(y), Le(b) and Le(a)), whereas the CLR MGL (macrophage galactose/N-acetylgalactosamine-specific C-type lectin) recognizes GalNAc.	Mannose	107-114	C-type lectin domain containing 10A	Homo sapiens	210-275
19021583-1	2008	MBL (mannan-binding lectin; also called mannose-binding lectin) is a circulating C-type lectin with a collagen-like region synthesized mainly by the liver.	Mannose	40-47	mannose binding lectin 2	Homo sapiens	0-3
19021583-1	2008	MBL (mannan-binding lectin; also called mannose-binding lectin) is a circulating C-type lectin with a collagen-like region synthesized mainly by the liver.	Mannose	40-47	mannose binding lectin 2	Homo sapiens	5-26
18848942-8	2008	TFF1 also bound to human serum albumin-conjugated mannose and glucose.	Mannose	50-57	trefoil factor 1	Homo sapiens	0-4
18772280-0	2008	Mutation in the DC-SIGN cytoplasmic triacidic cluster motif markedly attenuates receptor activity for phagocytosis and endocytosis of mannose-containing ligands by human myeloid cells.	Mannose	134-141	CD209 molecule	Homo sapiens	16-23
18067170-6	2008	Furthermore, we demonstrated that all of CD34(+) HSCs of both origins bound specifically to PV Mannose, whereas 33-47% bound to PV Maltose.	Mannose	95-102	CD34 molecule	Homo sapiens	41-45
19017977-5	2008	LPLA(2) is a high mannose type glycoprotein found in lysosomes, suggesting that the released enzyme might be reincorporated into alveolar macrophages via a mannose or mannose phosphate receptor.	Mannose	18-25	phospholipase A2, group XV	Mus musculus	0-7
18980683-6	2008	CONCLUSION: Because mannose is known to block induction of tumor necrosis factor by macrophages, a regimen of mannose either prior to and/or post development of symptoms minimized these responses.	Mannose	20-27	tumor necrosis factor	Homo sapiens	59-80
18980683-6	2008	CONCLUSION: Because mannose is known to block induction of tumor necrosis factor by macrophages, a regimen of mannose either prior to and/or post development of symptoms minimized these responses.	Mannose	110-117	tumor necrosis factor	Homo sapiens	59-80
18702607-2	2008	In mammals, collectin family members (e.g., mannose-binding lectin [MBL]) and the structurally related protein C1q bind to apoptotic cells and stimulate macrophage phagocytosis via a conserved collagenous tail domain.	Mannose	44-51	mannose binding lectin 2	Homo sapiens	68-71
18702607-2	2008	In mammals, collectin family members (e.g., mannose-binding lectin [MBL]) and the structurally related protein C1q bind to apoptotic cells and stimulate macrophage phagocytosis via a conserved collagenous tail domain.	Mannose	44-51	complement C1q A chain	Homo sapiens	111-114
18491227-8	2008	Furthermore, we found that N-glycans of M4 E-cadherin were modified in immature high mannose type, suggesting that it could not depart to Golgi apparatus.	Mannose	85-92	cadherin 1	Homo sapiens	43-53
19057812-1	2008	The present study investigated the prevalence of mutations in the -550 (H/L) and -221 (X/Y) mannose-binding lectin (MBL) gene promoter regions and their impact on infection by human immunodeficiency virus 1 (HIV-1) in a population of 128 HIV-1 seropositive and 97 seronegative patients.	Mannose	92-99	mannose binding lectin 2	Homo sapiens	116-119
18703501-7	2008	Mass spectrometry experiments showed that CA IX contains an intramolecular disulfide bridge (Cys(119)-Cys(299)) and a unique N-linked glycosylation site (Asn(309)) that bears high mannose-type glycan structures.	Mannose	180-187	carbonic anhydrase 9	Homo sapiens	42-47
18272428-8	2008	The saa mutant of strain T141, in which adherence was mannose resistant, did not show a significant decrease in adherence compared to the wild type, suggesting a Saa-independent mechanism of adherence.	Mannose	54-61	STEC autoagglutinating adhesin	Escherichia coli	4-7
18067170-7	2008	In addition, the majority of B cells (CD19(+)), T cells (CD3(+)), monocytes (CD14(+)), and erythrocytes (CD235a(+)) bound to PV Mannose, but a lower percentage interacted with PV Maltose.	Mannose	128-135	CD19 molecule	Homo sapiens	38-42
18067170-7	2008	In addition, the majority of B cells (CD19(+)), T cells (CD3(+)), monocytes (CD14(+)), and erythrocytes (CD235a(+)) bound to PV Mannose, but a lower percentage interacted with PV Maltose.	Mannose	128-135	CD14 molecule	Homo sapiens	77-81
18067170-7	2008	In addition, the majority of B cells (CD19(+)), T cells (CD3(+)), monocytes (CD14(+)), and erythrocytes (CD235a(+)) bound to PV Mannose, but a lower percentage interacted with PV Maltose.	Mannose	128-135	glycophorin A (MNS blood group)	Homo sapiens	105-111
18590741-3	2008	While ERGIC-53 is known to be a lectin-type mannose binding protein, the role of MCFD2 in the secretory pathway is comparatively unclear.	Mannose	44-51	lectin, mannose binding 1	Homo sapiens	6-14
18613275-8	2008	Although the average serum IDUA activity was relatively low at 12.6 +/- 8.1 units/ml in mice with stable expression, a relatively high percentage of enzyme contained the mannose 6-phosphorylation necessary for uptake by other cells.	Mannose	170-177	iduronidase, alpha-L	Mus musculus	27-31
18592362-0	2008	Mannose-binding lectin MBL2 gene polymorphisms and outcome of hepatitis C virus-infected patients.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	23-27
18592362-1	2008	INTRODUCTION: Mannose-binding lectin (MBL) is involved in host"s response to several infections including hepatitis B but little is known about MBL and hepatitis C virus (HCV) infection.	Mannose	14-21	mannose binding lectin 2	Homo sapiens	38-41
18633526-0	2008	Reagent switchable stereoselective beta(1,2) mannoside mannosylation: OH-2 of mannose is a privileged acceptor.	Mannose	78-85	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	35-43
18637753-0	2008	Detrimental effects of mannose-binding lectin (MBL2) promoter genotype XA/XA on HIV-1 vertical transmission and AIDS progression.	Mannose	23-30	mannose binding lectin 2	Homo sapiens	47-51
18637753-1	2008	BACKGROUND: The literature on the involvement of mannose-binding lectin (MBL) in human immunodeficiency virus (HIV) transmission and acquired immunodeficiency syndrome (AIDS) is conflicting.	Mannose	49-56	mannose binding lectin 2	Homo sapiens	73-76
19180724-0	2008	The interaction of mannose binding lectin (MBL) with mannose containing glycopeptides and the resultant potential impact on invasive fungal infection.	Mannose	19-26	mannose-binding lectin (protein C) 2	Mus musculus	43-46
19180724-0	2008	The interaction of mannose binding lectin (MBL) with mannose containing glycopeptides and the resultant potential impact on invasive fungal infection.	Mannose	53-60	mannose-binding lectin (protein C) 2	Mus musculus	43-46
18597806-4	2008	Our data demonstrate that Mermaid interacts with high mannose structures present on HIV-1 gp120 and thereby inhibits HIV-1 binding to DC-SIGN on DCs.	Mannose	54-61	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	90-95
18724009-4	2008	TNSALP (787T) and TNSALP (787T &gt; C) were synthesized similarly as a high-mannose-type 66-kDa form, becoming an 80-kDa form.	Mannose	76-83	alkaline phosphatase, biomineralization associated	Homo sapiens	0-6
18724009-4	2008	TNSALP (787T) and TNSALP (787T &gt; C) were synthesized similarly as a high-mannose-type 66-kDa form, becoming an 80-kDa form.	Mannose	76-83	alkaline phosphatase, biomineralization associated	Homo sapiens	18-24
18474364-1	2008	A series of beta-C-glycosylic ketones were prepared starting from d-glucose, d-xylose, d-mannose, and cellobiose.	Mannose	87-96	colony stimulating factor 2 receptor subunit beta	Homo sapiens	12-18
18566427-5	2008	Digestion of gp120 with endoglycosidase H abrogates the binding of SP-A, indicating that the high mannose structures on gp120 are the target of the collectin.	Mannose	98-105	surfactant protein A1	Homo sapiens	67-71
18602571-2	2008	OBJECTIVE: This study evaluated the effects of mannose-binding lectin-2 (MBL2) alleles on HIV-1 disease progression and central nervous system (CNS) impairment in children.	Mannose	47-54	mannose binding lectin 2	Homo sapiens	73-77
18566427-5	2008	Digestion of gp120 with endoglycosidase H abrogates the binding of SP-A, indicating that the high mannose structures on gp120 are the target of the collectin.	Mannose	98-105	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	120-125
18566427-3	2008	Our data demonstrate that SP-A binds to HIV in a calcium-dependent manner that is inhibitable by mannose and EDTA.	Mannose	97-104	surfactant protein A1	Homo sapiens	26-30
18434410-0	2008	An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies.	Mannose	139-146	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	156-161
18566427-5	2008	Digestion of gp120 with endoglycosidase H abrogates the binding of SP-A, indicating that the high mannose structures on gp120 are the target of the collectin.	Mannose	98-105	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	13-18
18381078-2	2008	In this work, ADAM10 was found to contain high-mannose and complex-type glycans.	Mannose	47-54	ADAM metallopeptidase domain 10	Homo sapiens	14-20
18538572-3	2008	The identification of the ER chaperones GRP94 and BiP as binding partners for the mannose-binding proteins OS-9 and XTP3-B, indicates that these protein complexes bind to aberrant proteins and direct them to the Hrd1 dislocation and ubiquitylation complex in the ER membrane.	Mannose	82-89	heat shock protein 90 beta family member 1	Homo sapiens	40-45
18538572-3	2008	The identification of the ER chaperones GRP94 and BiP as binding partners for the mannose-binding proteins OS-9 and XTP3-B, indicates that these protein complexes bind to aberrant proteins and direct them to the Hrd1 dislocation and ubiquitylation complex in the ER membrane.	Mannose	82-89	growth differentiation factor 10	Homo sapiens	50-53
18538572-3	2008	The identification of the ER chaperones GRP94 and BiP as binding partners for the mannose-binding proteins OS-9 and XTP3-B, indicates that these protein complexes bind to aberrant proteins and direct them to the Hrd1 dislocation and ubiquitylation complex in the ER membrane.	Mannose	82-89	OS9 endoplasmic reticulum lectin	Homo sapiens	107-111
18538572-3	2008	The identification of the ER chaperones GRP94 and BiP as binding partners for the mannose-binding proteins OS-9 and XTP3-B, indicates that these protein complexes bind to aberrant proteins and direct them to the Hrd1 dislocation and ubiquitylation complex in the ER membrane.	Mannose	82-89	endoplasmic reticulum lectin 1	Homo sapiens	116-122
18467454-0	2008	Functional characterization of HFR1, a high-mannose N-glycan-specific wheat lectin induced by Hessian fly larvae.	Mannose	44-51	uncharacterized protein LOC542941	Triticum aestivum	31-35
18571005-1	2008	Functional mannose-binding lectin (f-MBL) plays an important role in the innate neonatal immune system.	Mannose	11-18	mannose-binding lectin family member 3, pseudogene	Homo sapiens	37-40
18348874-1	2008	The possibility of post-translational modifications of mannose binding lectin (MBL) leading to functional impairment of the MBL pathway and the presence of anti-MBL autoantibodies were reported earlier in rheumatoid arthritis (RA).	Mannose	55-62	mannose binding lectin 2	Homo sapiens	79-82
18410496-7	2008	Here we demonstrate that Mid2p contains a single high mannose N-linked glycan at position Asn-35.	Mannose	54-61	Mid2p	Saccharomyces cerevisiae S288C	25-30
18348874-1	2008	The possibility of post-translational modifications of mannose binding lectin (MBL) leading to functional impairment of the MBL pathway and the presence of anti-MBL autoantibodies were reported earlier in rheumatoid arthritis (RA).	Mannose	55-62	mannose binding lectin 2	Homo sapiens	124-127
18348874-1	2008	The possibility of post-translational modifications of mannose binding lectin (MBL) leading to functional impairment of the MBL pathway and the presence of anti-MBL autoantibodies were reported earlier in rheumatoid arthritis (RA).	Mannose	55-62	mannose binding lectin 2	Homo sapiens	124-127
18320567-2	2008	We have identified an ALG3 homolog (HpALG3) coding for a dolichyl-phosphate-mannose dependent alpha-1,3-mannosyltransferase in the methylotrophic yeast Hansenula polymorpha.	Mannose	76-83	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	22-26
18546696-4	2008	The EDB data show that glyoxylic acid, 4-methylphthalic acid, monosaccharides (fructose and mannose), and disaccharides (maltose and lactose) did not crystallize and existed as metastable droplets at low relative humidity (RH).	Mannose	92-99	vesicle associated membrane protein 8	Homo sapiens	4-7
18198210-1	2008	MAb 2G12 neutralizes HIV-1 by binding with high affinity to a cluster of high-mannose oligosaccharides on the envelope glycoprotein, gp120.	Mannose	78-85	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	133-138
18322703-8	2008	Since MAGP-36 is known to bind to mannan, MAGP-36 might be involved in mannose transport in the S3 segment.	Mannose	71-78	microfibril associated protein 4	Rattus norvegicus	6-13
18322703-8	2008	Since MAGP-36 is known to bind to mannan, MAGP-36 might be involved in mannose transport in the S3 segment.	Mannose	71-78	microfibril associated protein 4	Rattus norvegicus	42-49
18473874-1	2008	Mannose-binding lectin (or mannan-binding lectin, MBL) may have an influence on susceptibility to infection in patients given chemotherapy to induce remission or as conditioning before stem cell transplantation.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	50-53
18285495-10	2008	Gas chromatography revealed that recombinant MSP2(P44)-18 is modified by glucose, galactose, xylose, mannose, and trace amounts of other glycosyl residues.	Mannose	101-108	interferon induced protein 44	Homo sapiens	50-53
18436959-2	2008	The wild-type (wt) protein binds with high affinity to mannose-rich oligosaccharides on the surface of gp120 through two quasi-symmetric sites, located in domains A and B.	Mannose	55-62	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	103-108
18272394-6	2008	Mass spectrometric analysis revealed the expression of the full-length protein and that the glycosylated IL-1ra contained high mannose glycoforms that ranged from Man(9)GlcNAc(2) to Man(14)GlcNAc(2).	Mannose	127-134	interleukin 1 receptor antagonist	Homo sapiens	105-111
18653905-1	2008	Mannose-binding lectin (MBL) is an important component of the immune defence able to bind to repeating mannose based structural patterns typical of microbial surface (bacteria, viruses, fungi, parasites) leading to opsonization and phagocytosis, and activation of the complement pathway resulting in lysis of the pathogen.	Mannose	103-110	mannose binding lectin 2	Homo sapiens	0-22
18653905-1	2008	Mannose-binding lectin (MBL) is an important component of the immune defence able to bind to repeating mannose based structural patterns typical of microbial surface (bacteria, viruses, fungi, parasites) leading to opsonization and phagocytosis, and activation of the complement pathway resulting in lysis of the pathogen.	Mannose	103-110	mannose binding lectin 2	Homo sapiens	24-27
18385798-6	2008	In addition, the transcript of GnT-V (the enzyme that catalyzes the addition of N-acetylglucosamine to the core mannose of di- and tri-antennary N-glycans through a beta1-6 linkage) was analyzed by semiquantitative RT-PCR.	Mannose	112-119	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	31-36
18061677-3	2008	The CRD of human Langerin, which was expressed as a soluble protein in the periplasm of E. coli, was crystallized both alone and in the presence of two sugars, followed by X-ray analyses to resolutions of 2.5A for apo-Langerin and to 1.6A and 2.1A for the complexes with mannose and maltose, respectively.	Mannose	271-278	CD207 molecule	Homo sapiens	17-25
18070119-2	2008	The glycolipid lipoarabinomannan (LAM), in particular its mannose cap, has been shown to inhibit phagolysosome fusion and to induce immunosuppressive IL-10 production via interaction with the mannose receptor or DC-SIGN.	Mannose	58-65	interleukin 10	Homo sapiens	150-155
18385798-6	2008	In addition, the transcript of GnT-V (the enzyme that catalyzes the addition of N-acetylglucosamine to the core mannose of di- and tri-antennary N-glycans through a beta1-6 linkage) was analyzed by semiquantitative RT-PCR.	Mannose	112-119	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	165-172
18178556-7	2008	In vivo labeling of the mutant with [3H]Man and in vitro labeling of membranes with GDP-[3H]Man confirmed that NCgl2106/Rv2188c catalyzed the second mannose addition in PIM biosynthesis, a function previously ascribed to PimB/Rv0557.	Mannose	149-156	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	169-172
17960739-8	2007	CD9P-1 was shown to exhibit more than 40 different N-glycans, essentially composed of complex and high mannose-type structures.	Mannose	103-110	prostaglandin F2 receptor inhibitor	Homo sapiens	0-6
18369574-8	2008	Mannose was more effective than DXM in inhibiting MPO activity and restoring SOD activity.	Mannose	0-7	myeloperoxidase	Rattus norvegicus	50-53
17983654-1	2008	Early work examining the interactions of IL-2 and the urinary glycoprotein uromodulin led to the suggestion that IL-2 was a lectin with specificity for high-mannose and mannan ligands.	Mannose	157-164	uromodulin	Homo sapiens	75-85
17983654-1	2008	Early work examining the interactions of IL-2 and the urinary glycoprotein uromodulin led to the suggestion that IL-2 was a lectin with specificity for high-mannose and mannan ligands.	Mannose	157-164	interleukin 2	Homo sapiens	113-117
17983654-3	2008	In an attempt to verify the reported interaction between IL-2 and mannose containing carbohydrate ligands we studied two biologically active forms of IL-2 using various techniques including affinity chromatography, equilibrium dialysis, and NMR methods.	Mannose	66-73	interleukin 2	Homo sapiens	57-61
17983654-3	2008	In an attempt to verify the reported interaction between IL-2 and mannose containing carbohydrate ligands we studied two biologically active forms of IL-2 using various techniques including affinity chromatography, equilibrium dialysis, and NMR methods.	Mannose	66-73	interleukin 2	Homo sapiens	150-154
18215164-0	2008	The relative contribution of mannose salvage pathways to glycosylation in PMI-deficient mouse embryonic fibroblast cells.	Mannose	29-36	mannose phosphate isomerase	Mus musculus	74-77
18215164-3	2008	Imported or salvaged mannose is directly phosphorylated by hexokinase, whereas fructose 6-phosphate from glucose is converted to mannose 6-phosphate by phosphomannose isomerase (PMI).	Mannose	21-28	mannose phosphate isomerase	Mus musculus	178-181
18215164-4	2008	Normally, PMI provides the majority of mannose for glycan synthesis.	Mannose	39-46	mannose phosphate isomerase	Mus musculus	10-13
18215164-6	2008	In PMI-null cells, imported mannose and salvaged mannose make a significant contribution to N-glycosylation.	Mannose	28-35	mannose phosphate isomerase	Mus musculus	3-6
18215164-6	2008	In PMI-null cells, imported mannose and salvaged mannose make a significant contribution to N-glycosylation.	Mannose	49-56	mannose phosphate isomerase	Mus musculus	3-6
18215164-7	2008	When these cells were grown in mannose-free medium along with the mannosidase inhibitor, swainsonine, to block the salvage pathways, N-glycosylation of DNase I was almost completely eliminated.	Mannose	31-38	deoxyribonuclease I	Mus musculus	152-159
18215164-11	2008	From these data, we conclude that PMI-null cells can salvage mannose from both endogenous and external glycoconjugates via lysosomal and nonlysosomal degradation pathways.	Mannose	61-68	mannose phosphate isomerase	Mus musculus	34-37
18800177-1	2008	Beta-mannosidase (EC 3.2.1.25, MANB) dissects the non-reducing end of N-linked mannose moieties of glycoproteins in eukaryotic cells.	Mannose	79-86	mannosidase beta	Homo sapiens	0-16
18800177-1	2008	Beta-mannosidase (EC 3.2.1.25, MANB) dissects the non-reducing end of N-linked mannose moieties of glycoproteins in eukaryotic cells.	Mannose	79-86	mannosidase alpha class 2B member 1	Homo sapiens	31-35
17890101-2	2008	Here, we performed pharmacokinetic studies in mice with two preparations of a monoclonal IgG1 antibody enriched for complex type or high mannose type oligosaccharides at the Fc glycosylation site.	Mannose	137-144	LOC105243590	Mus musculus	89-93
18577465-9	2008	In addition, it shows that both wild type and TDII FGFR3 interact with the mannose-specific lectin ERGIC-53.	Mannose	75-82	fibroblast growth factor receptor 3	Homo sapiens	51-56
18577465-9	2008	In addition, it shows that both wild type and TDII FGFR3 interact with the mannose-specific lectin ERGIC-53.	Mannose	75-82	lectin, mannose binding 1	Homo sapiens	99-107
18003979-3	2008	Although in vitro, at low concentrations, ERManI removes only one specific mannose residue, at very high concentrations it can excise up to four alpha1,2-linked mannose residues.	Mannose	75-82	mannosidase alpha class 1B member 1	Homo sapiens	42-48
18003979-3	2008	Although in vitro, at low concentrations, ERManI removes only one specific mannose residue, at very high concentrations it can excise up to four alpha1,2-linked mannose residues.	Mannose	161-168	mannosidase alpha class 1B member 1	Homo sapiens	42-48
17913713-8	2007	The substantial expression of high mannose and complex type N-glycans terminated with Lewisx and Lewisy sequences suggests that sperm glycoproteins are highly decorated with ligands for DC-SIGN.	Mannose	35-42	CD209 molecule	Homo sapiens	186-193
17658575-0	2007	High-mannose-specific deglycosylation of HIV-1 gp120 induced by resistance to cyanovirin-N and the impact on antibody neutralization.	Mannose	5-12	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	47-52
17658575-3	2007	Genotypic and phenotypic characterization of resistant env clones indicated that 3-5 high-mannose residues from 289 to 448 in the C2-C4 region of gp120 were mutated and correlated with the resistance levels.	Mannose	90-97	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	146-151
17658575-6	2007	For the first time, our data have collectively defined the high-mannose residues on gp120 affecting CV-N activity, and demonstrated that CBA-escape HIV-1 has increased sensitivity to immunoglobulins and sera from HIV patients, and particularly to V3 loop-directed MAbs.	Mannose	64-71	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	84-89
17983270-5	2007	The mannose-binding protein cyanovirin-N, the 2G12 mAb to a mannose-dependent gp120 epitope, and MCLR-specific mAbs inhibited IL-10 expression, as did enzymatic removal of gp120 mannose moieties, whereas inhibitors of signaling via CD4, CCR5, or CXCR4 were ineffective.	Mannose	60-67	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	78-83
17957800-6	2008	A high-mannose form of gp100, as protein or as tumor lysate, not only interacted specifically with DC through DC-SIGN but also resulted in an enhanced antigen presentation to gp100-specific CD4(+) T cells.	Mannose	7-14	premelanosome protein	Homo sapiens	23-28
17957800-6	2008	A high-mannose form of gp100, as protein or as tumor lysate, not only interacted specifically with DC through DC-SIGN but also resulted in an enhanced antigen presentation to gp100-specific CD4(+) T cells.	Mannose	7-14	premelanosome protein	Homo sapiens	175-180
18264945-6	2008	However, the structural characteristics for the aberrant IgA1 showed a drastic increase in the neutral N-glycans; in particular, 25% of the sugar chains in the aberrant IgA1 were the high mannose-type as compared with approximately 5%-6% in the serum IgA1 and tonsillar IgA1.	Mannose	188-195	immunoglobulin heavy constant alpha 1	Homo sapiens	57-61
18264945-6	2008	However, the structural characteristics for the aberrant IgA1 showed a drastic increase in the neutral N-glycans; in particular, 25% of the sugar chains in the aberrant IgA1 were the high mannose-type as compared with approximately 5%-6% in the serum IgA1 and tonsillar IgA1.	Mannose	188-195	immunoglobulin heavy constant alpha 1	Homo sapiens	169-173
18264945-6	2008	However, the structural characteristics for the aberrant IgA1 showed a drastic increase in the neutral N-glycans; in particular, 25% of the sugar chains in the aberrant IgA1 were the high mannose-type as compared with approximately 5%-6% in the serum IgA1 and tonsillar IgA1.	Mannose	188-195	immunoglobulin heavy constant alpha 1	Homo sapiens	169-173
18264945-6	2008	However, the structural characteristics for the aberrant IgA1 showed a drastic increase in the neutral N-glycans; in particular, 25% of the sugar chains in the aberrant IgA1 were the high mannose-type as compared with approximately 5%-6% in the serum IgA1 and tonsillar IgA1.	Mannose	188-195	immunoglobulin heavy constant alpha 1	Homo sapiens	169-173
17921350-13	2007	Bead-to-cell adhesion was inhibited by mannose, which also inhibits Flo11-dependent flocculation in vivo, further suggesting that this in vitro system is a useful model for the study of fungal adhesion.	Mannose	39-46	Flo11p	Saccharomyces cerevisiae S288C	68-73
17890508-12	2007	Taking into consideration such MBL-AJ peculiarities as its carbohydrate specificity, the presence of a conserved region forming the mannose-binding site, common antigenic determinants with human MBL, and participation in defense reactions, it is possible that MBL-AJ belongs to the family of evolutionary conserved mannan-binding proteins.	Mannose	132-139	mannose binding lectin 2	Homo sapiens	31-34
17983270-0	2007	HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells.	Mannose	12-20	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	6-11
17983270-5	2007	The mannose-binding protein cyanovirin-N, the 2G12 mAb to a mannose-dependent gp120 epitope, and MCLR-specific mAbs inhibited IL-10 expression, as did enzymatic removal of gp120 mannose moieties, whereas inhibitors of signaling via CD4, CCR5, or CXCR4 were ineffective.	Mannose	4-11	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	78-83
17983270-5	2007	The mannose-binding protein cyanovirin-N, the 2G12 mAb to a mannose-dependent gp120 epitope, and MCLR-specific mAbs inhibited IL-10 expression, as did enzymatic removal of gp120 mannose moieties, whereas inhibitors of signaling via CD4, CCR5, or CXCR4 were ineffective.	Mannose	4-11	interleukin 10	Homo sapiens	126-131
17983270-5	2007	The mannose-binding protein cyanovirin-N, the 2G12 mAb to a mannose-dependent gp120 epitope, and MCLR-specific mAbs inhibited IL-10 expression, as did enzymatic removal of gp120 mannose moieties, whereas inhibitors of signaling via CD4, CCR5, or CXCR4 were ineffective.	Mannose	4-11	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	172-177
17983270-5	2007	The mannose-binding protein cyanovirin-N, the 2G12 mAb to a mannose-dependent gp120 epitope, and MCLR-specific mAbs inhibited IL-10 expression, as did enzymatic removal of gp120 mannose moieties, whereas inhibitors of signaling via CD4, CCR5, or CXCR4 were ineffective.	Mannose	4-11	CD4 molecule	Homo sapiens	232-235
17983270-5	2007	The mannose-binding protein cyanovirin-N, the 2G12 mAb to a mannose-dependent gp120 epitope, and MCLR-specific mAbs inhibited IL-10 expression, as did enzymatic removal of gp120 mannose moieties, whereas inhibitors of signaling via CD4, CCR5, or CXCR4 were ineffective.	Mannose	4-11	C-C motif chemokine receptor 5	Homo sapiens	237-241
17983270-5	2007	The mannose-binding protein cyanovirin-N, the 2G12 mAb to a mannose-dependent gp120 epitope, and MCLR-specific mAbs inhibited IL-10 expression, as did enzymatic removal of gp120 mannose moieties, whereas inhibitors of signaling via CD4, CCR5, or CXCR4 were ineffective.	Mannose	4-11	C-X-C motif chemokine receptor 4	Homo sapiens	246-251
17983270-5	2007	The mannose-binding protein cyanovirin-N, the 2G12 mAb to a mannose-dependent gp120 epitope, and MCLR-specific mAbs inhibited IL-10 expression, as did enzymatic removal of gp120 mannose moieties, whereas inhibitors of signaling via CD4, CCR5, or CXCR4 were ineffective.	Mannose	60-67	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	78-83
17978585-2	2007	The first of the three mannose groups is attached to an intermediate to generate Man-GlcN-(acyl)PI by the first mannosyltransferase (GPI-MT-I).	Mannose	23-30	phosphatidylinositol glycan anchor biosynthesis class M	Homo sapiens	133-141
17915943-1	2007	In order to investigate the dynamic strength of the interaction between lung surfactant protein D (SP-D) and different sugars, maltose, mannose, glucose, and galactose, we have used an atomic force microscope to monitor the interaction on a single molecule scale.	Mannose	136-143	surfactant protein D	Homo sapiens	72-97
17915943-1	2007	In order to investigate the dynamic strength of the interaction between lung surfactant protein D (SP-D) and different sugars, maltose, mannose, glucose, and galactose, we have used an atomic force microscope to monitor the interaction on a single molecule scale.	Mannose	136-143	surfactant protein D	Homo sapiens	99-103
17915943-3	2007	Under these dynamic conditions, SP-D binds strongest to d-mannose and weakest to maltose and d-galactose.	Mannose	56-65	surfactant protein D	Homo sapiens	32-36
17978585-6	2007	PfPIG-M partially restored cell surface expression of the GPI-anchored protein CD59 in PIG-M deficient mammalian cells, and first mannose transfer activity in vitro; however, this was not the case for GPI14.	Mannose	130-137	GPI mannosyltransferase 1	Sus scrofa	2-7
17653692-1	2007	OBJECTIVE: Mannose-binding lectin (MBL2) is a collectin molecule able to activate the complement system and the subsequent inflammatory mechanisms.	Mannose	11-18	mannose binding lectin 2	Homo sapiens	35-39
17621594-0	2007	VIPL has sugar-binding activity specific for high-mannose-type N-glycans, and glucosylation of the alpha1,2 mannotriosyl branch blocks its binding.	Mannose	50-57	lectin, mannose binding 2 like	Homo sapiens	0-4
17621594-7	2007	Competition with several high-mannose-type N-glycans inhibited VIPL binding, and indicated that VIPL recognizes the Manalpha1-2Manalpha1-2Man sequence.	Mannose	30-37	lectin, mannose binding 2 like	Homo sapiens	63-67
17621594-7	2007	Competition with several high-mannose-type N-glycans inhibited VIPL binding, and indicated that VIPL recognizes the Manalpha1-2Manalpha1-2Man sequence.	Mannose	30-37	lectin, mannose binding 2 like	Homo sapiens	96-100
17407769-2	2007	Easier synthetic access to C1 in mannose, as compared to C3 in galactose, for attachment of affinity-enhancing triazoles rendered a synthetic advantage.	Mannose	33-40	serpin family G member 1	Homo sapiens	27-32
17785817-11	2007	The BTN2A1 of tumor cells such as HEK293T have more high-mannose moieties in comparison to HUVECs, and those high-mannose moieties are instrumental for binding to DC-SIGN.	Mannose	57-64	butyrophilin subfamily 2 member A1	Homo sapiens	4-10
17785817-11	2007	The BTN2A1 of tumor cells such as HEK293T have more high-mannose moieties in comparison to HUVECs, and those high-mannose moieties are instrumental for binding to DC-SIGN.	Mannose	114-121	butyrophilin subfamily 2 member A1	Homo sapiens	4-10
17692467-8	2007	Pgp isolated from MES-SA/Dx5 cells contains at least two different complex N-glycans--one high mannose tree, detected by GNA, and one branched hybrid oligosaccharide-capped with terminal sialic acids, detected by SNA and MAA.	Mannose	95-102	ATP binding cassette subfamily B member 1	Homo sapiens	0-3
17869647-1	2007	Mannose-binding lectin is an important constituent of the innate immune system, the serum levels of which are greatly affected by polymorphisms of the MBL2 gene: three polymorphisms in exon 1, as well as nucleotide variations in the promoter region of the gene, have been associated with protein deficiency and some infectious and autoimmune disease.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	151-155
18051874-3	2007	alpha-1,6-mannosyltransferases gene (och1) encodes the enzyme that initiates the first step of out-chain elongation of high mannose type N-glycan in yeast, which is different from that in human.	Mannose	124-131	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	37-41
17522223-1	2007	Human immunodeficiency virus type 1 (HIV-1) envelope (gp120) binding to DC-SIGN, a C-type lectin that can facilitate HIV infection in cis and in trans, is largely dependent on high-mannose-content moieties.	Mannose	181-188	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	54-59
17592722-12	2007	It was shown that the presence of Fbs1 perturb the activity of PNGase toward high-mannose-type glycopeptides.	Mannose	82-89	F-box protein 2	Homo sapiens	34-38
17592722-12	2007	It was shown that the presence of Fbs1 perturb the activity of PNGase toward high-mannose-type glycopeptides.	Mannose	82-89	N-glycanase 1	Homo sapiens	63-69
17554527-11	2007	The method was evaluated by genotyping two SNPs of the human mannose-binding lectin gene (MBL2) and one SNP of the cytochrome P450 gene CYP2D6.	Mannose	61-68	mannose binding lectin 2	Homo sapiens	90-94
17522223-1	2007	Human immunodeficiency virus type 1 (HIV-1) envelope (gp120) binding to DC-SIGN, a C-type lectin that can facilitate HIV infection in cis and in trans, is largely dependent on high-mannose-content moieties.	Mannose	181-188	CD209 molecule	Homo sapiens	72-79
17606910-6	2007	N-glycan-dependent QC of folding (UDP-Glc:glycoprotein glucosyltransferase, calreticulin, and/or calnexin) was present and active in some but not all protists containing at least five mannose residues in their N-glycans and was absent in protists lacking Man.	Mannose	184-191	calreticulin	Homo sapiens	76-88
17606910-6	2007	N-glycan-dependent QC of folding (UDP-Glc:glycoprotein glucosyltransferase, calreticulin, and/or calnexin) was present and active in some but not all protists containing at least five mannose residues in their N-glycans and was absent in protists lacking Man.	Mannose	184-191	calnexin	Homo sapiens	97-105
17519279-1	2007	GPI mannosyltransferase I (GPI-MT-I) transfers the first mannose to a GPI-anchor precursor, glucosamine-(acyl)phosphatidylinositol [GlcN-(acyl)PI].	Mannose	57-64	phosphatidylinositol glycan anchor biosynthesis class M	Homo sapiens	27-35
17513174-0	2007	Association of polymorphisms in the first exon of mannose binding lectin gene (MBL2) in Brazilian patients with HCV infection.	Mannose	50-57	mannose binding lectin 2	Homo sapiens	79-83
17331070-2	2007	The serotype A mannan contained beta-1,2-linked mannose residues attached to alpha-1,3-linked mannose residues and alpha-1,6-linked branching mannose residues.	Mannose	48-55	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	32-40
17582096-5	2007	Compositional and structural studies of the carbohydrates of bovine milk MUC15 showed that the glycans are composed of fucose, galactose, mannose, N-acetylgalactosamine, N-acetylglycosamine, and sialic acid.	Mannose	138-145	mucin 15, cell surface associated	Bos taurus	73-78
17493577-4	2007	RNAi of VCP induces preferential accumulation of alphaTCR with less mannose residues, suggesting its retention within the ER.	Mannose	68-75	valosin containing protein	Homo sapiens	8-11
17442667-1	2007	Mannan-binding protein (MBP) is a C-type mammalian lectin specific for mannose and N-acetylglucosamine.	Mannose	71-78	myelin basic protein	Homo sapiens	0-22
17442667-1	2007	Mannan-binding protein (MBP) is a C-type mammalian lectin specific for mannose and N-acetylglucosamine.	Mannose	71-78	myelin basic protein	Homo sapiens	24-27
17466984-2	2007	Here, we demonstrate that the disruption of Golgi alpha-mannosidase II activity by swainsonine in human embryonic kidney cells is capable of inducing a novel class of hybrid-type glycosylation containing a partially processed mannose moiety.	Mannose	226-233	mannosidase alpha class 2A member 1	Homo sapiens	44-70
17587672-2	2007	CPE, crude polysaccharide extract isolated from the rhizome of C. xanthorrhiza using 0.1 N NaOH, consisted of arabinose (18.69%), galactose (14.0%), glucose (50.67%), mannose (12.97%), rhamnose (2.73%), and xylose (0.94%), with an average molecular weight of 33,000 Da.	Mannose	167-174	carboxypeptidase E	Mus musculus	0-3
17369495-4	2007	We observed that p110alpha PI-3K was required for phagocytosis of IgG-opsonized and nonopsonized zymosan in differentiated THP-1 cells, and the latter was inhibitable by mannose.	Mannose	170-177	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Homo sapiens	17-26
17502612-8	2007	We demonstrate that entry of FVIII into human dendritic cells (DC) leading to T cell activation, is mediated by mannose-terminating glycans on FVIII.	Mannose	112-119	coagulation factor VIII	Homo sapiens	29-34
17502612-8	2007	We demonstrate that entry of FVIII into human dendritic cells (DC) leading to T cell activation, is mediated by mannose-terminating glycans on FVIII.	Mannose	112-119	coagulation factor VIII	Homo sapiens	143-148
17502612-11	2007	The interaction between FVIII and CD206 was blocked by VWF, suggesting that, under physiological conditions, the intrinsic mannose-dependent immunogenicity of FVIII is quenched by endogenous immunochaperones.	Mannose	123-130	coagulation factor VIII	Homo sapiens	24-29
17502612-11	2007	The interaction between FVIII and CD206 was blocked by VWF, suggesting that, under physiological conditions, the intrinsic mannose-dependent immunogenicity of FVIII is quenched by endogenous immunochaperones.	Mannose	123-130	mannose receptor C-type 1	Homo sapiens	34-39
17502612-11	2007	The interaction between FVIII and CD206 was blocked by VWF, suggesting that, under physiological conditions, the intrinsic mannose-dependent immunogenicity of FVIII is quenched by endogenous immunochaperones.	Mannose	123-130	von Willebrand factor	Homo sapiens	55-58
17502612-11	2007	The interaction between FVIII and CD206 was blocked by VWF, suggesting that, under physiological conditions, the intrinsic mannose-dependent immunogenicity of FVIII is quenched by endogenous immunochaperones.	Mannose	123-130	coagulation factor VIII	Homo sapiens	159-164
17509076-6	2007	By contrast, the K650M mutation affecting the tyrosine kinase 2 (TK2) domain produced heavy phosphorylation of the nonglycosylated and mannose-rich isoforms that impaired receptor trafficking through the Golgi network.	Mannose	135-142	tyrosine kinase 2	Homo sapiens	46-63
17509076-6	2007	By contrast, the K650M mutation affecting the tyrosine kinase 2 (TK2) domain produced heavy phosphorylation of the nonglycosylated and mannose-rich isoforms that impaired receptor trafficking through the Golgi network.	Mannose	135-142	tyrosine kinase 2	Homo sapiens	65-68
17408659-7	2007	High-affinity CFTR inhibition was abolished by MalH-lectin heat denaturation, protease digestion, or competition by mannose or unconjugated lectin.	Mannose	116-123	cystic fibrosis transmembrane conductance regulator	Mus musculus	14-18
17348701-6	2007	These results emphasize the possibility to conjugate mannose at position 6, allowing the incorporation of hydrophobic groups at the anomeric position to interact with hydrophobic residues in the carbohydrate recognition domain of DC-SIGN, increasing binding affinities.	Mannose	53-60	CD209 molecule	Homo sapiens	230-237
17251309-2	2007	Complex oligosaccharides present on Chinese hamster ovary cell-expressed glucocerebrosidase (GCase) are enzymatically remodeled into a mannose core, facilitating mannose receptor-mediated uptake into macrophages.	Mannose	135-142	glucosidase, beta, acid	Mus musculus	93-98
17251309-9	2007	Increased MBL binding was observed for all forms of GCase having larger mannose structures than those of Cerezyme, which could influence pharmacokinetic behavior.	Mannose	72-79	mannose binding lectin 2	Homo sapiens	10-13
17251309-9	2007	Increased MBL binding was observed for all forms of GCase having larger mannose structures than those of Cerezyme, which could influence pharmacokinetic behavior.	Mannose	72-79	glucosidase, beta, acid	Mus musculus	52-57
17123566-5	2007	Moreover, we observed that the NL4.3-2G12-resistant virus, with the N295K mutation in gp120, became significantly more sensitive to several mannose-specific lectins.	Mannose	140-147	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	86-91
17485663-6	2007	In vitro studies have suggested that IgG-G0 antibodies gain the capacity to activate the complement pathway via mannose-binding lectin (MBL), which could contribute to antibody-mediated inflammation.	Mannose	112-119	mannose-binding lectin (protein C) 2	Mus musculus	136-139
17229727-2	2007	Recently, we identified and characterized an ATP-dependent hexokinase (StHK) from the hyperthermophilic archaeon Sulfolobus tokodaii, which can phosphorylate a broad range of sugar substrates, including glucose, mannose, glucosamine, and N-acetylglucosamine.	Mannose	212-219	hexokinase 1	Homo sapiens	59-69
17188016-3	2007	This mutant CD expressed in rodent cells reaches the lysosome and is stable as single-chain polypeptide, bears high-mannose type sugars, binds to pepstatin A and is enzymatically active, indicating that it is correctly folded.	Mannose	116-123	cathepsin D	Homo sapiens	12-14
17892219-5	2007	The mouse-adapted PR8 strain which lacks mannose-containing glycans from the head of its HA molecule was largely resistant to the antiviral activities of SP-D and the MMR in vitro and induced severed clinical disease following intranasal infection of mice.	Mannose	41-48	surfactant associated protein D	Mus musculus	154-158
17892219-5	2007	The mouse-adapted PR8 strain which lacks mannose-containing glycans from the head of its HA molecule was largely resistant to the antiviral activities of SP-D and the MMR in vitro and induced severed clinical disease following intranasal infection of mice.	Mannose	41-48	ATPase, class II, type 9B	Mus musculus	167-170
17222190-5	2007	Using purified recombinant mannose-recognition domain of FimH, we identified a glycosylphosphatidylinositol-anchored receptor, CD48, as a putative HBMEC receptor for FimH.	Mannose	27-34	CD48 molecule	Homo sapiens	127-131
17178768-6	2007	The CL(uptake) in the liver decreased with coadministration of lactoferrin, a ligand for the low-density lipoprotein receptor-related protein (LRP) and the asialoglycoprotein (ASGP) receptors in normal mice, and in lrpap1((-/-)) mice, which have a hereditary deficiency of LRP; In contrast, CL(uptake) was not affected by mannose, whereas that of t-PA decreased with both ligands and in the lrpap1((-/-)) mice.	Mannose	322-329	lactotransferrin	Mus musculus	63-74
17150970-1	2007	The dendritic cell surface receptor DC-SIGN and the closely related endothelial cell receptor DC-SIGNR specifically recognize high mannose N-linked carbohydrates on viral pathogens.	Mannose	131-138	CD209 molecule	Homo sapiens	36-43
17150970-1	2007	The dendritic cell surface receptor DC-SIGN and the closely related endothelial cell receptor DC-SIGNR specifically recognize high mannose N-linked carbohydrates on viral pathogens.	Mannose	131-138	C-type lectin domain family 4 member M	Homo sapiens	94-102
17150970-4	2007	The molecular basis of this enhancement has been investigated by determining crystal structures of DC-SIGN bound to a synthetic six-mannose fragment of a high mannose N-linked oligosaccharide, Manalpha1-2Manalpha1-3[Manalpha1-2Manalpha1-6]Manalpha1-6Man and to the disaccharide Manalpha1-2Man.	Mannose	132-139	CD209 molecule	Homo sapiens	99-106
17222001-4	2007	The method is applied to the analysis of six SNPs in the mannose-binding lectin gene (MBL2).	Mannose	57-64	mannose binding lectin 2	Homo sapiens	86-90
17222001-12	2007	We analyzed six SNPs of the mannose-binding lectin gene (MBL2) using genomic DNA from 27 patients, representing a total of 74 variant nucleotide positions.	Mannose	28-35	mannose binding lectin 2	Homo sapiens	57-61
17024473-7	2007	Methylation analysis of the carbohydrate moieties of Hpf2p indicated that this protein contained both N- and O-linked mannose chains.	Mannose	118-125	Pst1p	Saccharomyces cerevisiae S288C	53-58
17514488-8	2007	SP-D had greater NA inhibitory activity than mannose-binding lectin, which in turn had greater activity than SP-A.	Mannose	45-52	surfactant protein A1	Homo sapiens	109-113
17311586-2	2007	We report that the major GPI that accumulates in mcd4-174 in vivo is Man(2)-GlcN-(acyl-Ins)PI, consistent with proposals that Mcd4p adds phosphoethanolamine to the first mannose of yeast GPI precursors.	Mannose	170-177	phosphatidylinositol glycan anchor biosynthesis class N	Homo sapiens	49-53
17311586-3	2007	Mcd4p-dependent modification of GPIs can partially be bypassed in the mcd4-174/gpi11 double mutant and in mcd4Delta; mutants by high-level expression of PIG-B and GPI10, which respectively encode the human and yeast mannosyltransferases that add the third mannose of the GPI precursor.	Mannose	256-263	mannose-ethanolamine phosphotransferase MCD4	Saccharomyces cerevisiae S288C	0-5
17311586-3	2007	Mcd4p-dependent modification of GPIs can partially be bypassed in the mcd4-174/gpi11 double mutant and in mcd4Delta; mutants by high-level expression of PIG-B and GPI10, which respectively encode the human and yeast mannosyltransferases that add the third mannose of the GPI precursor.	Mannose	256-263	phosphatidylinositol glycan anchor biosynthesis class B	Sus scrofa	153-158
17311586-3	2007	Mcd4p-dependent modification of GPIs can partially be bypassed in the mcd4-174/gpi11 double mutant and in mcd4Delta; mutants by high-level expression of PIG-B and GPI10, which respectively encode the human and yeast mannosyltransferases that add the third mannose of the GPI precursor.	Mannose	256-263	putative glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase	Saccharomyces cerevisiae S288C	163-168
17311586-4	2007	Rescue of mcd4Delta; by GPI10 indicates that Mcd4p-dependent addition of EthN-P to the first mannose of GPIs is not obligatory for transfer of the third mannose by Gpi10p.	Mannose	93-100	mannose-ethanolamine phosphotransferase MCD4	Saccharomyces cerevisiae S288C	45-50
17073943-4	2007	EXO(OVA) can be taken up by DC through LFA-1/CD54 and C-type lectin/mannose (glucosamine)-rich C-type lectin receptor (CLR) interactions.	Mannose	68-75	a disintegrin and metallopeptidase domain 11	Mus musculus	28-30
18045231-5	2007	Glucose/mannose specific lectins bound weaker to eggs when pre-incubated with the glycoprotein bovine lactotransferrin.	Mannose	8-15	lactotransferrin	Bos taurus	102-118
17361091-7	2007	These results may be due to the comparably lower expressions of mannose-bind lectins and some of toll-like receptors (TLRs) such as TLR-5, -6 and -9, necessary mediators to develop Th1 immune responses.	Mannose	64-71	negative elongation factor complex member C/D, Th1l	Mus musculus	181-184
16530268-7	2007	CRD1 and CRD2 showed 34% and 30% identity with that of mannose-binding lectin from Japanese lamprey (Lethenteron japonicum), respectively.	Mannose	55-62	CORD1	Homo sapiens	0-4
17093057-10	2007	Using mutant CHO lines altered in the processing of N-linked carbohydrates, we show that the high-mannose glycoform of contactin strongly binds neurofascin-155, its glial partner at paranodes.	Mannose	98-105	neurofascin	Homo sapiens	144-155
17177443-1	2006	The Golgi glycosyltransferase, N-acetylglucosaminyltransferase I (GnT-I), catalyzes the transfer of a GlcNAc residue from the donor UDP-GlcNAc to the C2-hydroxyl group of a mannose residue in the trimannosyl core of the Man5GlcNAc2-Asn-X oligosaccharide.	Mannose	173-180	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	66-71
17088551-0	2006	Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module.	Mannose	106-113	N-glycanase 1	Mus musculus	69-88
17050773-8	2006	Both in patients with IgAN and in control subjects, IgA binding to the GalNAc-specific lectin Helix Aspersa and to mannose-binding lectin was much stronger for pIgA than for mIgA.	Mannose	115-122	IGAN1	Homo sapiens	22-26
17050773-8	2006	Both in patients with IgAN and in control subjects, IgA binding to the GalNAc-specific lectin Helix Aspersa and to mannose-binding lectin was much stronger for pIgA than for mIgA.	Mannose	115-122	immunoglobulin heavy constant alpha	Mus musculus	22-25
17050773-8	2006	Both in patients with IgAN and in control subjects, IgA binding to the GalNAc-specific lectin Helix Aspersa and to mannose-binding lectin was much stronger for pIgA than for mIgA.	Mannose	115-122	phosphatidylinositol glycan anchor biosynthesis class A	Homo sapiens	160-164
17050773-8	2006	Both in patients with IgAN and in control subjects, IgA binding to the GalNAc-specific lectin Helix Aspersa and to mannose-binding lectin was much stronger for pIgA than for mIgA.	Mannose	115-122	immunoglobulin heavy constant alpha	Mus musculus	174-178
17084390-8	2006	The cytoplasmic/nuclear localization of a plant lectin that has a high affinity for high-mannose and complex N-glycans and specifically interacts with conspecific glycoproteins suggests that N-glycosylated proteins might be more important in the cytoplasm and nucleus than is currently believed.	Mannose	89-96	F-box protein PP2-B11-like	Nicotiana tabacum	48-54
17088551-7	2006	These studies demonstrate that the C-terminal domain binds to the mannose moieties of N-linked oligosaccharide chains, and we further show that it enhances the activity of the mouse PNGase core domain, presumably by increasing the affinity of mouse PNGase for the glycan chains of misfolded glycoproteins.	Mannose	66-73	N-glycanase 1	Mus musculus	182-188
17088551-7	2006	These studies demonstrate that the C-terminal domain binds to the mannose moieties of N-linked oligosaccharide chains, and we further show that it enhances the activity of the mouse PNGase core domain, presumably by increasing the affinity of mouse PNGase for the glycan chains of misfolded glycoproteins.	Mannose	66-73	N-glycanase 1	Mus musculus	249-255
17090929-1	2006	UDP-N-Acetylglucosamine: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT-I) is an essential enzyme in the conversion of high mannose type oligosaccharide to the hybrid or complex type.	Mannose	145-152	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	89-94
16987498-5	2006	The ER stress-induced protein EDEM1 regulates disposal of folding-defective glycoproteins and has been described as a mannose-binding lectin.	Mannose	118-125	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	30-35
16982895-6	2006	A central cluster of hydrophilic CD1d residues (Asp(153), Thr(156), Ser(76), Arg(79)) interacts with the phosphate, inositol, and alpha1-alpha6-linked mannose of the headgroup, whereas additional specificity for the alpha1- and alpha2-linked mannose is conferred by Thr(159).	Mannose	151-158	CD1d1 antigen	Mus musculus	33-37
17042779-0	2006	Saccharomyces cerevisiae alpha1,6-mannosyltransferase has a catalytic potential to transfer a second mannose molecule.	Mannose	101-108	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	25-53
17042779-1	2006	In yeast, the N-linked oligosaccharide modification in the Golgi apparatus is initiated by alpha1,6-mannosyltransferase (encoded by the OCH1 gene) with the addition of mannose to the Man(8)GlcNAc(2) or Man(9)GlcNAc(2) endoplasmic reticulum intermediates.	Mannose	168-175	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	91-119
17042779-1	2006	In yeast, the N-linked oligosaccharide modification in the Golgi apparatus is initiated by alpha1,6-mannosyltransferase (encoded by the OCH1 gene) with the addition of mannose to the Man(8)GlcNAc(2) or Man(9)GlcNAc(2) endoplasmic reticulum intermediates.	Mannose	168-175	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	136-140
17042779-4	2006	The recombinant Och1p efficiently transferred a mannose to Man(8)GlcNAc(2)-PA and Man(9)GlcNAc(2)-PA acceptors, while Man(5)GlcNAc(2)-PA, which completely lacks alpha1,2-linked mannose residues, was not used as an acceptor.	Mannose	48-55	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	16-21
17042779-4	2006	The recombinant Och1p efficiently transferred a mannose to Man(8)GlcNAc(2)-PA and Man(9)GlcNAc(2)-PA acceptors, while Man(5)GlcNAc(2)-PA, which completely lacks alpha1,2-linked mannose residues, was not used as an acceptor.	Mannose	177-184	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	16-21
17042779-6	2006	Analysis of the product revealed that a second mannose was attached at the 6-O-position of alpha1,3-linked mannose branching from the alpha1,6-linked mannose that is attached to beta1,4-linked mannose of Man(10)GlcNAc(2)-PA produced by the original activity of Och1p.	Mannose	47-54	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	261-266
17042779-7	2006	Our results indicate that Och1p has the potential to transfer two mannoses from GDP-mannose, and strictly recognizes the overall structure of high mannose type oligosaccharide.	Mannose	66-74	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	26-31
17042779-7	2006	Our results indicate that Och1p has the potential to transfer two mannoses from GDP-mannose, and strictly recognizes the overall structure of high mannose type oligosaccharide.	Mannose	66-73	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	26-31
17015733-1	2006	The lectin pathway of complement is considered to be the most ancient complement pathway as inferred from identification of ancient homologs of mannose-binding lectin (MBL) and MBL-associated serine proteases (MASPs) in some invertebrates.	Mannose	144-151	mannose binding lectin 2	Danio rerio	168-171
17015733-6	2006	The other is an authentic MBL with mannose specificity.	Mannose	35-42	mannose binding lectin 2	Danio rerio	26-29
16982895-6	2006	A central cluster of hydrophilic CD1d residues (Asp(153), Thr(156), Ser(76), Arg(79)) interacts with the phosphate, inositol, and alpha1-alpha6-linked mannose of the headgroup, whereas additional specificity for the alpha1- and alpha2-linked mannose is conferred by Thr(159).	Mannose	151-158	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6	Mus musculus	130-143
16982895-6	2006	A central cluster of hydrophilic CD1d residues (Asp(153), Thr(156), Ser(76), Arg(79)) interacts with the phosphate, inositol, and alpha1-alpha6-linked mannose of the headgroup, whereas additional specificity for the alpha1- and alpha2-linked mannose is conferred by Thr(159).	Mannose	242-249	CD1d1 antigen	Mus musculus	33-37
16982895-6	2006	A central cluster of hydrophilic CD1d residues (Asp(153), Thr(156), Ser(76), Arg(79)) interacts with the phosphate, inositol, and alpha1-alpha6-linked mannose of the headgroup, whereas additional specificity for the alpha1- and alpha2-linked mannose is conferred by Thr(159).	Mannose	242-249	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6	Mus musculus	130-143
16982895-7	2006	The additional two mannoses in PIM4, relative to PIM2, are located at the distal 6" carbon of the alpha1-alpha6-linked mannose and would project away from the CD1d binding groove for interaction with the TCR.	Mannose	19-27	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6	Mus musculus	98-111
16982895-7	2006	The additional two mannoses in PIM4, relative to PIM2, are located at the distal 6" carbon of the alpha1-alpha6-linked mannose and would project away from the CD1d binding groove for interaction with the TCR.	Mannose	19-27	CD1d1 antigen	Mus musculus	159-163
16982895-7	2006	The additional two mannoses in PIM4, relative to PIM2, are located at the distal 6" carbon of the alpha1-alpha6-linked mannose and would project away from the CD1d binding groove for interaction with the TCR.	Mannose	19-26	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6	Mus musculus	98-111
16982895-7	2006	The additional two mannoses in PIM4, relative to PIM2, are located at the distal 6" carbon of the alpha1-alpha6-linked mannose and would project away from the CD1d binding groove for interaction with the TCR.	Mannose	19-26	CD1d1 antigen	Mus musculus	159-163
16987177-6	2006	This operon was also shown to activate a four-gene cluster located immediately downstream and encoding an Enzyme II (EII(Lev)) for a fructose/mannose sugar : phosphotransferase enzyme, which was found to negatively regulate the expression of fruA.	Mannose	142-149	fructan beta-fructosidase	Streptococcus mutans UA159	242-246
16926040-9	2006	In conclusion, ACLEC is able to attract neutrophils into the mice peritoneal cavity by mechanisms involving interactions of the lectin with cell-specific mannose recognition, leading to the release of COX-2-derived mediators and PAF.	Mannose	154-161	prostaglandin-endoperoxide synthase 2	Mus musculus	201-206
16647263-0	2006	High-mannose-type glycan modifications of dihydrofolate reductase using glycan-methotrexate conjugates.	Mannose	5-12	dihydrofolate reductase	Homo sapiens	42-65
16542855-3	2006	In this report the isolation and characterisation of cDNA transcripts encoding two mannose-binding lectin isoforms MBL-1 and MBL-2 from rainbow trout (Oncorhynchus mykiss) is presented.	Mannose	83-90	C-type mannose-binding lectin	Oncorhynchus mykiss	115-120
16542855-6	2006	The trout MBL-1 and MBL-2 contain the EPN motif of mannose-binding C-type lectins, important for mannose specificity and they are expressed exclusively in liver and spleen, respectively.	Mannose	51-58	C-type mannose-binding lectin	Oncorhynchus mykiss	10-15
16542855-6	2006	The trout MBL-1 and MBL-2 contain the EPN motif of mannose-binding C-type lectins, important for mannose specificity and they are expressed exclusively in liver and spleen, respectively.	Mannose	97-104	C-type mannose-binding lectin	Oncorhynchus mykiss	10-15
17309727-12	2006	In addition, we demonstrate that a plant-made antibody with triantennary high-mannose-type N-glycans has similar Fab functionality to its counterpart with biantennary complex N-glycans, but the former antibody interacts with protein A in a stronger manner and is more immunogenic than the latter.	Mannose	78-85	FA complementation group B	Homo sapiens	113-116
16814399-4	2006	Mannan binding lectin (MBL), the "recognition" molecule of the lectin pathway of complement activation, is homologous in structure to C1q, and binds in a calcium-dependent manner to terminal mannose and GlcNAc residues which have been identified on the oligosaccharides N-linked to the Igs.	Mannose	191-198	mannose binding lectin 2	Homo sapiens	0-21
16814399-4	2006	Mannan binding lectin (MBL), the "recognition" molecule of the lectin pathway of complement activation, is homologous in structure to C1q, and binds in a calcium-dependent manner to terminal mannose and GlcNAc residues which have been identified on the oligosaccharides N-linked to the Igs.	Mannose	191-198	mannose binding lectin 2	Homo sapiens	23-26
17002903-0	2006	Diversity of the MBL2 gene in various Brazilian populations and the case of selection at the mannose-binding lectin locus.	Mannose	93-100	mannose binding lectin 2	Homo sapiens	17-21
17002903-1	2006	The mannose binding lectin (MBL2) polymorphism is responsible for a common immunodeficiency in the human species.	Mannose	4-11	mannose binding lectin 2	Homo sapiens	28-32
16682414-10	2006	In MDCK cells, which produce E-cadherin, a variant lacking both complex and high mannose/hybrid N-glycans functioned like a dominant positive displaying increased interaction with gamma-catenin and vinculin compared with the endogenous E-cadherin.	Mannose	81-88	cadherin 1	Canis lupus familiaris	29-39
16682414-10	2006	In MDCK cells, which produce E-cadherin, a variant lacking both complex and high mannose/hybrid N-glycans functioned like a dominant positive displaying increased interaction with gamma-catenin and vinculin compared with the endogenous E-cadherin.	Mannose	81-88	vinculin	Canis lupus familiaris	198-206
16682414-10	2006	In MDCK cells, which produce E-cadherin, a variant lacking both complex and high mannose/hybrid N-glycans functioned like a dominant positive displaying increased interaction with gamma-catenin and vinculin compared with the endogenous E-cadherin.	Mannose	81-88	cadherin 1	Canis lupus familiaris	236-246
16647263-1	2006	Various high-mannose-type glycan modifications of dihydrofolate reductase (DHFR) were achieved by ligand-based approach using glycan-methotrexate (MTX) conjugates as tight binding glycan bearing ligands for DHFR.	Mannose	13-20	dihydrofolate reductase	Homo sapiens	50-73
16647263-1	2006	Various high-mannose-type glycan modifications of dihydrofolate reductase (DHFR) were achieved by ligand-based approach using glycan-methotrexate (MTX) conjugates as tight binding glycan bearing ligands for DHFR.	Mannose	13-20	dihydrofolate reductase	Homo sapiens	75-79
16647263-1	2006	Various high-mannose-type glycan modifications of dihydrofolate reductase (DHFR) were achieved by ligand-based approach using glycan-methotrexate (MTX) conjugates as tight binding glycan bearing ligands for DHFR.	Mannose	13-20	dihydrofolate reductase	Homo sapiens	207-211
16672288-4	2006	Thus, core fucosylation is prevented by the presence of terminal alpha1-2 mannoses on the 6-antennae but not the 3-antennae of the trimannosyl core.	Mannose	74-82	adrenoceptor alpha 1D	Homo sapiens	65-73
16682406-4	2006	Results from screening of a glycan array demonstrate that only mouse SIGNR3 shares with human DC-SIGN the ability to bind both high mannose and fucose-terminated glycans in this format and to mediate endocytosis.	Mannose	132-139	CD209d antigen	Mus musculus	69-75
16530738-3	2006	The NBS-mediated cleavage of 4,6-O-benzylidene acetals in the galactopyranoside series is therefore shown to conform to the regiochemistry observed in the corresponding gluco- and mannopyranoside series with preferential cleavage of the C6-O6 bond by an ionic mechanism.	Mannose	180-195	nibrin	Homo sapiens	4-7
16704983-3	2006	MCD4 is essential because Gpi10p, the mannosyltransferase adding the subsequent alpha1-2-linked mannose, requires substrates with an ethanolaminephosphate on the alpha1-4-linked mannose.	Mannose	96-103	mannose-ethanolamine phosphotransferase MCD4	Saccharomyces cerevisiae S288C	0-4
16704983-3	2006	MCD4 is essential because Gpi10p, the mannosyltransferase adding the subsequent alpha1-2-linked mannose, requires substrates with an ethanolaminephosphate on the alpha1-4-linked mannose.	Mannose	96-103	putative glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase	Saccharomyces cerevisiae S288C	26-32
16585136-6	2006	The spectra indicate that MUC1F N-glycans have compositions consistent with high-mannose structures (Hex(5-9)HexNAc(2)) and complex/hybrid-type glycans (NeuAc(0-3)Fuc(0-3)Hex(3-8)HexNAc(3-7)).	Mannose	81-88	mucin 1, cell surface associated	Homo sapiens	26-30
16704983-3	2006	MCD4 is essential because Gpi10p, the mannosyltransferase adding the subsequent alpha1-2-linked mannose, requires substrates with an ethanolaminephosphate on the alpha1-4-linked mannose.	Mannose	178-185	mannose-ethanolamine phosphotransferase MCD4	Saccharomyces cerevisiae S288C	0-4
16704983-3	2006	MCD4 is essential because Gpi10p, the mannosyltransferase adding the subsequent alpha1-2-linked mannose, requires substrates with an ethanolaminephosphate on the alpha1-4-linked mannose.	Mannose	178-185	putative glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase	Saccharomyces cerevisiae S288C	26-32
16990181-11	2006	These data indicate that endothelial carbohydrate determinants and corresponding ligands (namely, mannose-specific lectins) may be involved in the regulation of production and deposition of vWF.	Mannose	98-105	von Willebrand factor	Homo sapiens	190-193
16787095-1	2006	The X-ray crystal structures of mannose trimming enzyme drosophila Golgi alpha-mannosidase II (dGMII) complexed with the inhibitors mannostatin A (1) and an N-benzyl analogue (2) have been determined.	Mannose	32-39	alpha-Mannosidase class II a	Drosophila melanogaster	67-93
16740149-1	2006	The low-beta-amylase1 (lba1) mutant of Arabidopsis thaliana has reduced sugar-induced expression of Atbeta-Amy and shows pleiotropic phenotypes such as early flowering; short day-sensitive growth; and seed germination that is hypersensitive to glucose and abscisic acid and resistant to mannose.	Mannose	287-294	RNA helicase	Arabidopsis thaliana	4-21
16740149-1	2006	The low-beta-amylase1 (lba1) mutant of Arabidopsis thaliana has reduced sugar-induced expression of Atbeta-Amy and shows pleiotropic phenotypes such as early flowering; short day-sensitive growth; and seed germination that is hypersensitive to glucose and abscisic acid and resistant to mannose.	Mannose	287-294	RNA helicase	Arabidopsis thaliana	23-27
16787095-1	2006	The X-ray crystal structures of mannose trimming enzyme drosophila Golgi alpha-mannosidase II (dGMII) complexed with the inhibitors mannostatin A (1) and an N-benzyl analogue (2) have been determined.	Mannose	32-39	alpha-Mannosidase class II a	Drosophila melanogaster	95-100
16766650-0	2006	Leishmania beta-1,2-mannan is assembled on a mannose-cyclic phosphate primer.	Mannose	45-52	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	11-19
16766650-6	2006	Analysis of the mannan primer by Fourier transform ion-cyclotron resonance MS and various enzymatic and chemical treatments and comparison with authentic mannose (Man) phosphates indicated the presence of Man-alpha-1,4-cyclic phosphate.	Mannose	154-161	adrenoceptor alpha 1D	Homo sapiens	209-218
16600536-2	2006	Mannosylated bovine serum albumin (Man-BSA) with different numbers of mannoses and other mannosylated derivatives of lysozyme (LZM), soybean trypsin inhibitor (STI), superoxide dismutase (SOD) and bovine gamma-immunoglobulin (IgG) were synthesized.	Mannose	70-78	albumin	Homo sapiens	20-33
16567801-3	2006	UPIa presents a high level of terminally exposed mannose residues (located on Man(6)GlcNAc(2) to Man(9)GlcNAc(2)) that are capable of specifically interacting with FimH.	Mannose	49-56	uroplakin 1A	Homo sapiens	0-4
16567809-3	2006	Langerin binds and mediates uptake and degradation of glycoconjugates containing mannose and related sugars.	Mannose	81-88	CD207 molecule	Homo sapiens	0-8
16708401-2	2006	In this study we investigated whether TLR2 and collectins, surfactant protein A (SP-A) and mannose-binding lectin (MBL), interacted with A. otitidis.	Mannose	91-98	mannose binding lectin 2	Homo sapiens	115-118
16716913-6	2006	The isolated polysaccharide, named CSP-1, which has strong anti-oxidation activity, contains glucose, mannose and galactose in the ratio of 1:0.6:0.75.	Mannose	102-109	common salivary protein 1	Rattus norvegicus	35-40
16567801-4	2006	We have shown that this property is conserved not only in the mouse uroplakins but also in cattle and, even more importantly, in human UPIa, thus establishing the concept that UPIa is a major urothelial receptor in humans and other mammals for the mannose-specific FimH variant.	Mannose	248-255	uroplakin 1A	Homo sapiens	135-139
16567801-4	2006	We have shown that this property is conserved not only in the mouse uroplakins but also in cattle and, even more importantly, in human UPIa, thus establishing the concept that UPIa is a major urothelial receptor in humans and other mammals for the mannose-specific FimH variant.	Mannose	248-255	uroplakin 1A	Homo sapiens	176-180
16567801-5	2006	In contrast, our results indicate that most terminally exposed glycans of mouse UPIb are non-mannose residues, thus explaining the failure of FimH to bind to this UPIb.	Mannose	93-100	uroplakin 1B	Mus musculus	80-84
16691507-4	2006	The three-dimensional structure of such a receptor, p58/ERGIC-53, has been recently solved by x-ray crystallography, which is a mannose-selective lectin and contains two Ca(2+) ions.	Mannose	128-135	lectin, mannose binding 1	Homo sapiens	52-55
16574074-1	2006	The mannose-binding lectin (MBL), a pattern recognition serum protein, participates in the innate immune system of mammals as an opsonin.	Mannose	4-11	mannose-binding lectin family member 3, pseudogene	Homo sapiens	28-31
16423983-0	2006	The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose.	Mannose	93-100	C-type lectin domain containing 6A	Homo sapiens	39-47
16423983-2	2006	The carbohydrate-recognition domain (CRD) of Dectin-2 exhibited cation-dependent mannose/fucose-like lectin activity, with an IC(50) for mannose of approximately 20 mM compared to an IC(50) of 1.5 mM for the macrophage mannose receptor when assayed by similar methodology.	Mannose	81-88	C-type lectin domain containing 6A	Homo sapiens	45-53
16423983-2	2006	The carbohydrate-recognition domain (CRD) of Dectin-2 exhibited cation-dependent mannose/fucose-like lectin activity, with an IC(50) for mannose of approximately 20 mM compared to an IC(50) of 1.5 mM for the macrophage mannose receptor when assayed by similar methodology.	Mannose	137-144	C-type lectin domain containing 6A	Homo sapiens	45-53
16423983-8	2006	Glycan array analysis of the carbohydrate recognition by Dectin-2 indicated specific recognition of high-mannose structures (Man(9)GlcNAc(2)).	Mannose	105-112	C-type lectin domain containing 6A	Homo sapiens	57-65
16616922-0	2006	Mannose hyperbranched dendritic polymers interact with clustered organization of DC-SIGN and inhibit gp120 binding.	Mannose	0-7	CD209 molecule	Homo sapiens	81-88
16616922-0	2006	Mannose hyperbranched dendritic polymers interact with clustered organization of DC-SIGN and inhibit gp120 binding.	Mannose	0-7	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	101-106
16616922-2	2006	Surface plasmon resonance has been used to study the affinity of a glycodendritic polymer with 32 mannoses, to DC-SIGN.	Mannose	98-106	CD209 molecule	Homo sapiens	111-118
16691507-4	2006	The three-dimensional structure of such a receptor, p58/ERGIC-53, has been recently solved by x-ray crystallography, which is a mannose-selective lectin and contains two Ca(2+) ions.	Mannose	128-135	lectin, mannose binding 1	Homo sapiens	56-64
16691507-9	2006	Properties of these modeled complexes were studied to examine the nature of physicochemical forces involved in the complex formation and compared with p58/ERGIC-53-mannose complex.	Mannose	164-171	lectin, mannose binding 1	Homo sapiens	151-154
16691507-9	2006	Properties of these modeled complexes were studied to examine the nature of physicochemical forces involved in the complex formation and compared with p58/ERGIC-53-mannose complex.	Mannose	164-171	lectin, mannose binding 1	Homo sapiens	155-163
16764028-10	2006	0.1 mol/L mannose inhibited TNF-alpha expression induced by oligochitosan.	Mannose	10-17	tumor necrosis factor	Homo sapiens	28-37
16756569-2	2006	In a previous study, we demonstrated that the high mannose type of N-glycan of the envelope glycoprotein is closely related to PERV infectivity with respect to human cells.	Mannose	51-58	endogenous retrovirus group K member 20	Homo sapiens	83-104
16536439-4	2006	The apparent affinity constant of Con A binding to mannose was (8.7 +/- 2.8) x 10(5) and (3.9 +/- 0.2) x 10(6) M(-1) measured by QCM and SPR, respectively.	Mannose	51-58	sepiapterin reductase	Homo sapiens	137-140
16455649-2	2006	PIM glycolipids, having 2-4 mannose residues, can either be channeled into polar PIM species (with 6 Man residues) or hypermannosylated to form LM and LAM.	Mannose	28-35	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	0-3
16518621-5	2006	In this study, we purified an MBL from porcine serum by mannose affinity, ion exchange, and size exclusion chromatography and determined many of its characteristics.	Mannose	56-63	mannose binding lectin 2	Homo sapiens	30-33
16476447-2	2006	The high levels of kinase activity of the FGFR3-mutants cause uncompleted biosynthesis that results in the accumulation of the immature/mannose-rich, phosphorylated receptors in the endoplasmic reticulum (ER) and STATs activation.	Mannose	136-143	fibroblast growth factor receptor 3	Homo sapiens	42-47
16555815-4	2006	In the case of mannose, the high alpha selectivity observed with C-mannosylation was reversed to high beta selectivity if the C-5 alkoxyalkyl group were removed.	Mannose	15-22	complement C5	Homo sapiens	126-129
16431915-0	2006	EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming.	Mannose	102-109	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	0-5
16431915-0	2006	EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming.	Mannose	102-109	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	0-4
16431915-7	2006	Furthermore, overexpression of the E147Q EDEM3 mutant, which has the mutation in one of the conserved acidic residues essential for enzyme activity of alpha1,2-mannosidases, abolishes the stimulation of mannose trimming and greatly decreases the stimulation of ERAD by EDEM3.	Mannose	203-210	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	41-46
16595889-8	2006	Clustering of mannose residues on liposomal surfaces might be important in determining the binding affinity of mannosylated liposomes with MBP.	Mannose	14-21	myelin basic protein	Homo sapiens	139-142
16304048-6	2006	For proteins in the calnexin cycle, removal of the terminal mannose residue of the middle branch of the core N-linked glycan results in degradation.	Mannose	60-67	calnexin	Homo sapiens	20-28
16304048-7	2006	Inhibition of the enzyme that removes this mannose residue prevented pro-alphaIIb degradation in beta3-null murine megakaryocytes.	Mannose	43-50	calcium channel, voltage-dependent, beta 3 subunit	Mus musculus	97-102
16571816-4	2006	Biochemical studies with expressed wild-type (wt) and mutant proteins revealed that the mature GP5 contains high-mannose-type sugar moieties at all three sites.	Mannose	113-120	glycoprotein V platelet	Homo sapiens	95-98
17177794-8	2006	The combined results indicate that IDUA produced in cgl mutant seeds contains glycans primarily in the high-mannose form.	Mannose	108-115	alpha-L-iduronidase	Homo sapiens	35-39
16505041-4	2006	Binding assays were performed with radiolabeled parasites; CPE assays were performed with rabbit corneal epithelial cells as host cells; and the expression of MBP was detected by affinity chromatography of parasite extracts on mannose affinity columns and by immunohistochemical and Western blot analyses.	Mannose	227-234	myelin basic protein	Oryctolagus cuniculus	159-162
16043420-3	2005	Both Flo1-type and NewFlo yeast flocculation are inhibited by mannose.	Mannose	62-69	flocculin FLO1	Saccharomyces cerevisiae S288C	5-9
16221666-2	2006	The biosynthesis of PSMA in transfected COS-1 cells reveals a slow conversion of mannose-rich to complex glycosylated PSMA compatible with slow transport kinetics from the endoplasmic reticulum to the Golgi.	Mannose	81-88	putative N-acetylated-alpha-linked acidic dipeptidase	Canis lupus familiaris	20-24
16221666-3	2006	Importantly, mannose-rich PSMA persists as a trypsin-sensitive protein throughout its entire life cycle, and only Golgi-located PSMA glycoforms acquire trypsin resistance.	Mannose	13-20	putative N-acetylated-alpha-linked acidic dipeptidase	Canis lupus familiaris	26-30
16436111-5	2006	In primary macrophages, CPVL is glycosylated with high mannose residues and colocalizes with markers for endoplasmic reticulum, while in MO it is more disperse and less clearly associated with endoplasmic reticulum.	Mannose	55-62	carboxypeptidase vitellogenic like	Homo sapiens	24-28
17304538-3	2006	For example, calnexin and calreticulin (CRT) are molecular chaperones that recognize monoglucosylated forms of high-mannose-type glycans.	Mannose	116-123	calnexin	Homo sapiens	13-21
17304538-3	2006	For example, calnexin and calreticulin (CRT) are molecular chaperones that recognize monoglucosylated forms of high-mannose-type glycans.	Mannose	116-123	calreticulin	Homo sapiens	26-38
17304538-3	2006	For example, calnexin and calreticulin (CRT) are molecular chaperones that recognize monoglucosylated forms of high-mannose-type glycans.	Mannose	116-123	calreticulin	Homo sapiens	40-43
16092920-2	2005	We have previously shown that M. tuberculosis binds to human monocyte-derived dendritic cells mostly through the C-type lectin DC-SIGN (dendritic-cell-specific intercellular molecule-3-grabbing non-integrin)/CD209, and we have suggested that DC-SIGN may discriminate between mycobacterial species through recognition of the mannose-capping residues on the lipoglycan lipoarabinomannan of the bacterial envelope.	Mannose	324-331	CD209 molecule	Homo sapiens	127-134
16092920-2	2005	We have previously shown that M. tuberculosis binds to human monocyte-derived dendritic cells mostly through the C-type lectin DC-SIGN (dendritic-cell-specific intercellular molecule-3-grabbing non-integrin)/CD209, and we have suggested that DC-SIGN may discriminate between mycobacterial species through recognition of the mannose-capping residues on the lipoglycan lipoarabinomannan of the bacterial envelope.	Mannose	324-331	CD209 molecule	Homo sapiens	136-206
16092920-5	2005	We propose that M. tuberculosis recognition by DC-SIGN relies on both a potential difference of accessibility of lipoarabinomannan in its envelope and, more probably, on the binding of additional ligands, possibly including lipomannan, mannose-capped arabinomannan, as well as the mannosylated 19 kDa and 45 kDa [Apa (alanine/proline-rich antigen)] glycoproteins.	Mannose	236-243	CD209 molecule	Homo sapiens	47-54
16677572-1	2006	OBJECTIVE: To detect the serum level of mannose binding lectin (MBL) and its genovariation in systemic lupus erythematosus (SLE) patients and to investigate the role of MBL in the pathogenesis of SLE.	Mannose	40-47	mannose binding lectin 2	Homo sapiens	64-67
16226049-0	2006	Isolation and characterization of a glucose/mannose-specific lectin with stimulatory effect on nitric oxide production by macrophages from the emperor banana.	Mannose	44-51	lectin	Musa acuminata	61-67
16226049-3	2006	In this study, a glucose/mannose-specific lectin has been purified from the emperor banana by affinity chromatography on Affi-gel blue gel, ion exchange chromatography on Mono S and gel filtration by fast protein liquid chromatography on Superdex 75.	Mannose	25-32	lectin	Musa acuminata	42-48
16415006-1	2006	The C-type lectins DC-SIGN and DC-SIGNR bind mannose-rich glycans with high affinity.	Mannose	45-52	C-type lectin domain family 4 member M	Homo sapiens	31-39
16298151-6	2006	Treatment of AMs with both rabbit anti-mouse SAP polyclonal antibody and mannose-derived simple sugars, separately, blocked the SAP-induced inhibition of mycobacterial growth.	Mannose	73-80	amyloid P component, serum	Mus musculus	128-131
17179669-7	2006	CL-K1 showed Ca(2+)-dependent sugar binding activity of fucose and weakly mannose but not N-acetyl-galactosamine, N-acetyl-glucosamine, or maltose, though mannose-binding lectin (MBL) containing similar amino acid motif.	Mannose	74-81	CDC like kinase 1	Homo sapiens	0-5
16115771-1	2005	Inositol phosphate glycan pseudotetrasaccharides consisting of man-(alpha1-6)-man-(alpha1-4)-glcN-(alpha,beta1-6)-myo-inositol-1,2-cyclic phosphate possessing a sulfate group at either O-6 (compounds 3alpha,beta) or O-2 (compounds 4alpha,beta) of the terminal mannose have been prepared.	Mannose	260-267	adrenoceptor alpha 1D	Homo sapiens	68-76
16115771-1	2005	Inositol phosphate glycan pseudotetrasaccharides consisting of man-(alpha1-6)-man-(alpha1-4)-glcN-(alpha,beta1-6)-myo-inositol-1,2-cyclic phosphate possessing a sulfate group at either O-6 (compounds 3alpha,beta) or O-2 (compounds 4alpha,beta) of the terminal mannose have been prepared.	Mannose	260-267	adrenoceptor alpha 1D	Homo sapiens	83-91
16380916-4	2005	The effect on the cellular targeting of high-mannose and complex oligosaccharide-type oligosaccharide chains was tested with human LAL expressed in Pichia pastoris (phLAL) and CHO cells (chLAL), respectively.	Mannose	45-52	lipase A, lysosomal acid type	Homo sapiens	131-134
16043420-6	2005	We report that Flo11p-dependent flocculation is inhibited by mannose, but not by glucose, maltose or sucrose.	Mannose	61-68	Flo11p	Saccharomyces cerevisiae S288C	15-21
16299314-4	2005	Complement activation is initiated by the classical, alternative, or lectin pathway, with the latter requiring mannose-binding lectin (MBL, also known as mannose-binding protein).	Mannose	111-118	mannose-binding lectin (protein C) 2	Mus musculus	135-138
16208516-0	2005	An analysis of genetic variation across the MBL2 locus in Dutch Caucasians indicates that 3" haplotypes could modify circulating levels of mannose-binding lectin.	Mannose	139-146	mannose binding lectin 2	Homo sapiens	44-48
16299325-0	2005	Noncapsulated Klebsiella pneumoniae bearing mannose-containing O antigens is rapidly eradicated from mouse lung and triggers cytokine production by macrophages following opsonization with surfactant protein D.	Mannose	44-51	surfactant associated protein D	Mus musculus	188-208
16299325-3	2005	Noncapsulated mannose-containing O3 serotypes (K50/n and K55/n), which react efficiently with SP-D in vitro, triggered high levels of interleukin-1beta (IL-1beta) and IL-6 production.	Mannose	14-21	surfactant associated protein D	Mus musculus	94-98
16299325-3	2005	Noncapsulated mannose-containing O3 serotypes (K50/n and K55/n), which react efficiently with SP-D in vitro, triggered high levels of interleukin-1beta (IL-1beta) and IL-6 production.	Mannose	14-21	interleukin 1 beta	Mus musculus	134-151
16299325-3	2005	Noncapsulated mannose-containing O3 serotypes (K50/n and K55/n), which react efficiently with SP-D in vitro, triggered high levels of interleukin-1beta (IL-1beta) and IL-6 production.	Mannose	14-21	interleukin 1 beta	Mus musculus	153-161
16299325-3	2005	Noncapsulated mannose-containing O3 serotypes (K50/n and K55/n), which react efficiently with SP-D in vitro, triggered high levels of interleukin-1beta (IL-1beta) and IL-6 production.	Mannose	14-21	interleukin 6	Mus musculus	167-171
16299325-7	2005	These findings are consistent with in vitro results showing that production of IL-1beta and IL-6 mRNA and IL-6 protein by human macrophages exposed to mannose-bearing Klebsiella O serotypes is significantly increased by SP-D.	Mannose	151-158	interleukin 1 beta	Homo sapiens	79-87
16299325-7	2005	These findings are consistent with in vitro results showing that production of IL-1beta and IL-6 mRNA and IL-6 protein by human macrophages exposed to mannose-bearing Klebsiella O serotypes is significantly increased by SP-D.	Mannose	151-158	interleukin 6	Homo sapiens	92-96
16299325-7	2005	These findings are consistent with in vitro results showing that production of IL-1beta and IL-6 mRNA and IL-6 protein by human macrophages exposed to mannose-bearing Klebsiella O serotypes is significantly increased by SP-D.	Mannose	151-158	interleukin 6	Homo sapiens	106-110
16299325-7	2005	These findings are consistent with in vitro results showing that production of IL-1beta and IL-6 mRNA and IL-6 protein by human macrophages exposed to mannose-bearing Klebsiella O serotypes is significantly increased by SP-D.	Mannose	151-158	surfactant associated protein D	Mus musculus	220-224
16025538-8	2005	This analysis of N-glycans revealed that hEPO was modified to include paucimannosidic glycans containing two or three mannose residues with or without core fucose.	Mannose	118-125	erythropoietin	Homo sapiens	41-45
15946779-3	2005	Mannose binding lectin genes (MBL) and other genes such as those for myeloperoxidase (MPO) and Fcgamma receptor may aid in the control of infection post transplant.	Mannose	0-7	myeloperoxidase	Homo sapiens	69-84
16272342-0	2005	Decoupling of carbohydrate binding and MASP-2 autoactivation in variant mannose-binding lectins associated with immunodeficiency.	Mannose	72-79	MBL associated serine protease 2	Homo sapiens	39-45
15946779-3	2005	Mannose binding lectin genes (MBL) and other genes such as those for myeloperoxidase (MPO) and Fcgamma receptor may aid in the control of infection post transplant.	Mannose	0-7	myeloperoxidase	Homo sapiens	86-89
16311890-3	2005	Unexpectedly, glycoproteins containing high mannose-type N-glycans and a horseradish peroxidase were stained with LEA.	Mannose	44-51	Indole-3-acetic acid-induced protein ARG2-like	Solanum tuberosum	114-117
15987956-5	2005	Here, we show that the dolichylphosphomannose-dependent ALG9 mannosyltransferase is the exception from this rule and is required for the addition of two different alpha-1,2-linked mannose residues to the LLO.	Mannose	38-45	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	56-60
16079417-3	2005	Mutations in phosphomannomutase (PMM2) cause CDG-Ia by reducing the activity of PMM, which converts mannose (Man)-6-P to Man-1-P before formation of GDP-Man.	Mannose	100-107	phosphomannomutase 2	Homo sapiens	33-37
16079417-3	2005	Mutations in phosphomannomutase (PMM2) cause CDG-Ia by reducing the activity of PMM, which converts mannose (Man)-6-P to Man-1-P before formation of GDP-Man.	Mannose	100-107	LEM domain containing 3	Homo sapiens	121-126
16311890-4	2005	LEA blot analysis of the glycoproteins accompanied by treatment with exoglycosidase revealed that the binding site of LEA for the complex-type N-glycans was the N-acetyllactosaminyl side chains, whereas the proximal chitobiose core appeared to be the binding site of LEA for high mannose-type N-glycans.	Mannose	280-287	Indole-3-acetic acid-induced protein ARG2-like	Solanum tuberosum	118-121
16622944-3	2005	N-Glycans, consisting of a large repertoire of sialylated polyantennary chains and high-mannose structures, account for approximately 30% of the weight of human urinary THGP.	Mannose	88-95	uromodulin	Homo sapiens	169-173
16311890-4	2005	LEA blot analysis of the glycoproteins accompanied by treatment with exoglycosidase revealed that the binding site of LEA for the complex-type N-glycans was the N-acetyllactosaminyl side chains, whereas the proximal chitobiose core appeared to be the binding site of LEA for high mannose-type N-glycans.	Mannose	280-287	Indole-3-acetic acid-induced protein ARG2-like	Solanum tuberosum	118-121
16550916-2	2005	We identified the gene for FCMD and MEB, which encodes the fukutin protein and the protein O-linked mannose beta1, 2-N-acetylglucosaminyltransferase (POMGnT1), respectively.	Mannose	100-107	fukutin	Homo sapiens	27-31
16550916-2	2005	We identified the gene for FCMD and MEB, which encodes the fukutin protein and the protein O-linked mannose beta1, 2-N-acetylglucosaminyltransferase (POMGnT1), respectively.	Mannose	100-107	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)	Homo sapiens	150-157
16085208-3	2005	At non-cytotoxic concentrations, MT-II stimulated Fcgamma, complement, mannose and beta-glucan receptors-mediated phagocytosis, whereas MT-III stimulated only the mannose and beta-glucan receptors-mediated phagocytosis.	Mannose	71-78	metallothionein 2	Mus musculus	33-38
15917430-6	2005	Molecular structure comparison for Man9GlcNAc2 recognition by ConA and 2G12 indicates that 2G12 has a more restricted specificity to high mannose glycans of gp120 which correlates with kinetic analysis assessed by surface plasmon resonance (SPR) and ConA inhibits 2G12 binding to gp120 but 2G12 does not inhibit ConA binding to gp120.	Mannose	138-145	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	157-162
16085208-3	2005	At non-cytotoxic concentrations, MT-II stimulated Fcgamma, complement, mannose and beta-glucan receptors-mediated phagocytosis, whereas MT-III stimulated only the mannose and beta-glucan receptors-mediated phagocytosis.	Mannose	163-170	metallothionein 3	Mus musculus	136-142
16151975-0	2005	The metabolisable hexoses D-glucose and D-mannose enhance the expression of IRS-2 but not of IRS-1 in pancreatic beta-cells.	Mannose	40-49	insulin receptor substrate 2	Cricetulus griseus	76-81
15888732-10	2005	The loss of mannose-binding sites was accompanied by the loss of AQN1 in sperm extracts and the significant reduction in the sperm-oviduct binding.	Mannose	12-19	carbohydrate-binding protein AQN-1	Sus scrofa	65-69
15888732-11	2005	The oviductal epithelium was shown by GNA-lectin histochemistry and by SDS-PAGE and lectin blotting of the apical membrane fraction to express mannose components that could be recognized by AQN1.	Mannose	143-150	carbohydrate-binding protein AQN-1	Sus scrofa	190-194
15983039-4	2005	MR transductants generated in glycosylation mutant cell lines lacked most mannose internalization activity, but could internalize sulfated glycans.	Mannose	74-81	mannose receptor C-type 1	Homo sapiens	0-2
15983039-6	2005	Additional studies showed that, although mannose recognition was largely independent of the oligomerization state of the protein, recognition of sulfated carbohydrates was mostly mediated by self-associated MR and that, in SA0-MR, there was a higher proportion of oligomeric MR.	Mannose	41-48	mannose receptor C-type 1	Homo sapiens	227-229
15983039-6	2005	Additional studies showed that, although mannose recognition was largely independent of the oligomerization state of the protein, recognition of sulfated carbohydrates was mostly mediated by self-associated MR and that, in SA0-MR, there was a higher proportion of oligomeric MR.	Mannose	41-48	mannose receptor C-type 1	Homo sapiens	227-229
15983039-9	2005	(i) It is required for mannose recognition; and (ii) it modulates the tendency of MR to self-associate, effectively regulating the avidity of the CR domain for sulfated sugar ligands.	Mannose	23-30	mannose receptor C-type 1	Homo sapiens	82-84
16151975-0	2005	The metabolisable hexoses D-glucose and D-mannose enhance the expression of IRS-2 but not of IRS-1 in pancreatic beta-cells.	Mannose	40-49	insulin receptor substrate 1	Cricetulus griseus	93-98
16109954-6	2005	Their involvement in mannose adhesion was corroborated by the finding that a sortase (srtA) mutant of L. plantarum WCFS1 lost the capacity to agglutinate S. cerevisiae.	Mannose	21-28	class A sortase	Lactobacillus plantarum WCFS1	86-90
16116208-1	2005	Mannan-binding protein (MBP) is a C-type serum lectin that is known to be a host defense factor involved in innate immunity, and recognizes mannose, fucose, and N-acetylglucosamine residues.	Mannose	140-147	myelin basic protein	Homo sapiens	0-22
16116208-1	2005	Mannan-binding protein (MBP) is a C-type serum lectin that is known to be a host defense factor involved in innate immunity, and recognizes mannose, fucose, and N-acetylglucosamine residues.	Mannose	140-147	myelin basic protein	Homo sapiens	24-27
16116208-6	2005	Deglycosylation experiments indicated that the MBP ligands on meprins are high mannose- or complex-type N-glycans.	Mannose	79-86	myelin basic protein	Homo sapiens	47-50
16099912-1	2005	Mannose-binding lectin (MBL), a serum lectin that mediates innate immune functions including activation of the lectin complement pathway, binds to carbohydrates expressed on some viral glycoproteins.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
16240719-1	2005	The Mcd4 protein of Saccharomyces cerevisiae is probably involved in addition of the phosphoethanolamine moiety to the first mannose residue of the glycosylphosphatidylinositol precursor(s).	Mannose	125-132	mannose-ethanolamine phosphotransferase MCD4	Saccharomyces cerevisiae S288C	4-8
15812659-1	2005	The selectable marker gene phospho-mannose isomerase (pmi), which encodes the enzyme phospho-mannose isomerase (PMI) to enable selection of transformed cell lines on media containing mannose (Man), was evaluated for genetic transformation of papaya (Carica papaya L.).	Mannose	35-42	mannose phosphate isomerase	Homo sapiens	54-57
15812659-1	2005	The selectable marker gene phospho-mannose isomerase (pmi), which encodes the enzyme phospho-mannose isomerase (PMI) to enable selection of transformed cell lines on media containing mannose (Man), was evaluated for genetic transformation of papaya (Carica papaya L.).	Mannose	35-42	mannose phosphate isomerase	Homo sapiens	85-110
15812659-1	2005	The selectable marker gene phospho-mannose isomerase (pmi), which encodes the enzyme phospho-mannose isomerase (PMI) to enable selection of transformed cell lines on media containing mannose (Man), was evaluated for genetic transformation of papaya (Carica papaya L.).	Mannose	35-42	mannose phosphate isomerase	Homo sapiens	112-115
16216673-1	2005	The present study investigated the association between mannose-binding lectin (MBL) gene polymorphism and the susceptibility to human T-cell lymphotropic virus (HTLV) infection in a group of 83 HTLV-infected asymptomatic subjects (62 HTLV-1 and 21 HTLV-2) and 99 healthy controls.	Mannose	55-62	mannose binding lectin 2	Homo sapiens	79-82
16006591-7	2005	In contrast, V2R-R113W, -G201D, and -T204N were expressed in the ER and in the basolateral membrane as immature, high-mannose glycosylated, and mature complex-glycosylated proteins.	Mannose	118-125	arginine vasopressin receptor 2	Canis lupus familiaris	13-16
15953573-8	2005	ACL and AGL were inhibited by mannose/glucose and their derivatives.	Mannose	30-37	apolipoprotein C-IV	Mus musculus	0-3
15953573-8	2005	ACL and AGL were inhibited by mannose/glucose and their derivatives.	Mannose	30-37	amylo-1,6-glucosidase, 4-alpha-glucanotransferase	Mus musculus	8-11
15994813-1	2005	Mannose binding lectin (MBL) is a central component of the innate immune response and thus may be important for determining hepatitis B virus (HBV) persistence.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
15997205-10	2005	The recognition of lysosomal proteins by GlcNAc-phosphotransferase is mediated by protein structure, and a specific three-dimensional arrangement of lysine residues exposed on the surface of several enzymes has been shown to be critical for mannose phosphorylation.	Mannose	241-248	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta	Homo sapiens	41-66
15972690-1	2005	The mannose-binding lectin (MBL), a circulating pattern recognition molecule, recognizes a wide range of infectious agents with resultant initiation of the complement cascade in an Ab-independent manner.	Mannose	4-11	mannose-binding lectin (protein C) 2	Mus musculus	28-31
15886209-2	2005	LMAN1 is a type 1 transmembrane protein with homology to mannose-binding lectins.	Mannose	57-64	lectin, mannose binding 1	Homo sapiens	0-5
15950722-2	2005	Two of three human ficolins, L-ficolin and H-ficolin, are serum lectins that form complexes with mannose-binding lectin-associated serine proteases (MASPs) and play important roles in the lectin complement pathway.	Mannose	97-104	ficolin 2	Homo sapiens	29-38
15944324-0	2005	Mannose-containing molecular patterns are strong inducers of cyclooxygenase-2 expression and prostaglandin E2 production in human macrophages.	Mannose	0-7	prostaglandin-endoperoxide synthase 2	Homo sapiens	61-77
15950722-2	2005	Two of three human ficolins, L-ficolin and H-ficolin, are serum lectins that form complexes with mannose-binding lectin-associated serine proteases (MASPs) and play important roles in the lectin complement pathway.	Mannose	97-104	ficolin 3	Homo sapiens	43-52
15939292-2	2005	The pimA gene of mycobacteria encodes a alpha-mannosyltransferase involved in the transfer reaction of the very first mannose from GDP-mannose to the carrier lipid phosphatidyl-myo-inositol, a precursor in the synthesis of LAM.	Mannose	118-125	alpha-(1-2)-phosphatidylinositol mannosyltransferase	Mycobacterium tuberculosis H37Rv	4-8
15896325-2	2005	JEN1 mRNA decay is greatly accelerated upon the addition of a pulse of glucose, fructose or mannose to induced cell cultures.	Mannose	92-99	Jen1p	Saccharomyces cerevisiae S288C	0-4
15944324-1	2005	The induction of cyclooxygenase-2 (COX-2) and the production of PGE(2) in response to pathogen-associated molecular patterns decorated with mannose moieties were studied in human monocytes and monocyte-derived macrophages (MDM).	Mannose	140-147	prostaglandin-endoperoxide synthase 2	Homo sapiens	17-33
15944324-8	2005	Because COX-2 products can be both proinflammatory and immunomodulatory, these results disclose a signaling route triggered by mannose-decorated pathogen-associated molecular patterns, which can be involved in both the response to pathogens and the maintenance of homeostasis.	Mannose	127-134	prostaglandin-endoperoxide synthase 2	Homo sapiens	8-13
15944324-4	2005	Treatment with mannose-BSA, a weak agonist of the MR containing a lower ratio of attached sugar compared with pure polysaccharides, before the addition of mannan inhibited COX-2 expression, whereas this was not observed when agonists other than mannan and zymosan were used.	Mannose	15-22	prostaglandin-endoperoxide synthase 2	Homo sapiens	172-177
15950651-10	2005	Rec-hZPA interaction was disturbed by dextran sulphate (75% inhibition with 10 microM), fucose (67% inhibition with 1.5 microM), and mannose (69% inhibition with 333 mM).	Mannose	133-140	zona pellucida glycoprotein 2	Homo sapiens	4-8
15950652-3	2005	OBJECTIVE: To assess the interaction of human proacrosin/acrosin with mannose residues coupled to a protein backbone.	Mannose	70-77	acrosin	Homo sapiens	46-56
15950652-3	2005	OBJECTIVE: To assess the interaction of human proacrosin/acrosin with mannose residues coupled to a protein backbone.	Mannose	70-77	acrosin	Homo sapiens	49-56
15950652-7	2005	INTERVENTION(S): In vitro binding assay developed to assess proacrosin/acrosin-BSA-mannose interaction.	Mannose	83-90	acrosin	Homo sapiens	60-70
15950652-7	2005	INTERVENTION(S): In vitro binding assay developed to assess proacrosin/acrosin-BSA-mannose interaction.	Mannose	83-90	acrosin	Homo sapiens	63-70
15950652-8	2005	MAIN OUTCOME MEASURE(S): Proacrosin/acrosin binding to BSA-mannose; estimation of binding affinity.	Mannose	59-66	acrosin	Homo sapiens	25-35
15950652-8	2005	MAIN OUTCOME MEASURE(S): Proacrosin/acrosin binding to BSA-mannose; estimation of binding affinity.	Mannose	59-66	acrosin	Homo sapiens	28-35
15950652-9	2005	RESULT(S): All recombinant proteins of acrosin but Rec-6 (residues 1-59 of proacrosin) specifically bound to BSA-mannose.	Mannose	113-120	acrosin	Homo sapiens	39-46
15950652-9	2005	RESULT(S): All recombinant proteins of acrosin but Rec-6 (residues 1-59 of proacrosin) specifically bound to BSA-mannose.	Mannose	113-120	acrosin	Homo sapiens	75-85
15950652-13	2005	CONCLUSION(S): [1] Proacrosin interacts with mannose residues through binding sites located at both the N- and C-terminal portion of the protein, [2] the full-length protein is required for maximal BSA-mannose binding, and [3] binding sites are stabilized by noncovalent bonds and by disulfide linkages.	Mannose	45-52	acrosin	Homo sapiens	19-29
15950652-13	2005	CONCLUSION(S): [1] Proacrosin interacts with mannose residues through binding sites located at both the N- and C-terminal portion of the protein, [2] the full-length protein is required for maximal BSA-mannose binding, and [3] binding sites are stabilized by noncovalent bonds and by disulfide linkages.	Mannose	202-209	acrosin	Homo sapiens	19-29
15718224-0	2005	Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis.	Mannose	87-94	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	49-54
15788399-6	2005	The major sugar chains of ZPB were pauci and high mannose type chains that were similar in structure to the major neutral N-linked chain of the bovine zona.	Mannose	50-57	zona pellucida glycoprotein 4	Homo sapiens	26-29
15616123-1	2005	Human apolipoprotein B100 (apoB100) has 19 potential N-glycosylation sites, and 16 asparagine residues were reported to be occupied by high-mannose type, hybrid type, and monoantennary and biantennary complex type oligosaccharides.	Mannose	140-147	apolipoprotein B	Homo sapiens	6-25
15616123-1	2005	Human apolipoprotein B100 (apoB100) has 19 potential N-glycosylation sites, and 16 asparagine residues were reported to be occupied by high-mannose type, hybrid type, and monoantennary and biantennary complex type oligosaccharides.	Mannose	140-147	apolipoprotein B	Homo sapiens	27-34
15788390-1	2005	The solution structure of the 48-kDa IIA(Man)-HPr complex of the mannose branch of the Escherichia coli phosphotransferase system has been solved by NMR using conjoined rigid body/torsion angle-simulated annealing on the basis of intermolecular nuclear Overhauser enhancement data and residual dipolar couplings.	Mannose	65-72	haptoglobin-related protein	Homo sapiens	46-49
15760896-9	2005	These results suggest that the degradation of LQT2 mutant channels is mediated by the cytosolic proteasome in a process that involves mannose trimming, polyubiquitination, and deglycosylation of mutant channels.	Mannose	134-141	potassium voltage-gated channel subfamily H member 2	Homo sapiens	46-50
15711012-4	2005	However, CL-43, a bovine serum lectin, which evolved through duplication of the surfactant protein D gene in ruminants, prefers mannose and mannose-rich polysaccharides.	Mannose	128-135	surfactant protein D	Homo sapiens	80-100
15853952-2	2005	After binding mannose containing carbohydrate structures of foreign antigen, mbl initiates and regulates the inflammatory responses.	Mannose	14-21	mannose binding lectin 2	Homo sapiens	77-80
15537386-1	2005	GnTI (N-acetylglucosaminyltransferase I) is a Golgi-resident enzyme essential for the processing of high-mannose to hybrid and complex N-glycans.	Mannose	105-112	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	0-4
15537386-1	2005	GnTI (N-acetylglucosaminyltransferase I) is a Golgi-resident enzyme essential for the processing of high-mannose to hybrid and complex N-glycans.	Mannose	105-112	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	6-39
15657036-5	2005	Intracellular FGE contains a high mannose type N-glycan, which is processed to the complex type in secreted FGE.	Mannose	34-41	sulfatase modifying factor 1	Homo sapiens	14-17
15657036-5	2005	Intracellular FGE contains a high mannose type N-glycan, which is processed to the complex type in secreted FGE.	Mannose	34-41	sulfatase modifying factor 1	Homo sapiens	108-111
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Mannose	145-152	myelin basic protein	Homo sapiens	0-22
15819890-2	2005	Among them, a beta1,2-linked N-acetylglucosamine residue is introduced to the central mannose moiety of the core-fucosylated oligosaccharide by N-acetylglucosaminyltransferase VII.	Mannose	86-93	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	14-21
15634673-2	2005	Mannan-binding protein (MBP) is a C-type serum lectin and activates complement through the lectin pathway when it binds to ligand sugars such as mannose, N-acetylglucosamine, and fucose on microbes.	Mannose	145-152	myelin basic protein	Homo sapiens	24-27
15632136-5	2005	Yeast GPI7 is involved in the transfer of EtNP to the second mannose, but the corresponding mammalian enzyme has not yet been clarified.	Mannose	61-68	mannose-ethanolamine phosphotransferase LAS21	Saccharomyces cerevisiae S288C	6-10
15623507-0	2005	PIG-V involved in transferring the second mannose in glycosylphosphatidylinositol.	Mannose	42-49	phosphatidylinositol glycan anchor biosynthesis class V	Sus scrofa	0-5
15623507-4	2005	Therefore, four Dol-P-Man-dependent mannosyltransferases, GPI-MT-I, -MT-II, -MT-III, and -MT-IV for the first, second, third, and fourth mannoses, respectively, are required for generation of GPI.	Mannose	137-145	metallothionein 4	Homo sapiens	90-95
15613479-9	2005	Further data showed that the binding of GRFT to soluble gp120 was inhibited by the monosaccharides glucose, mannose, and N-acetylglucosamine but not by galactose, xylose, fucose, N-acetylgalactosamine, or sialic acid-containing glycoproteins.	Mannose	108-115	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	56-61
15632136-9	2005	PIG-O is a transferase that adds EtNP to the third mannose, rendering GPI capable of attaching to proteins.	Mannose	51-58	PIGO	Sus scrofa	0-5
15623507-6	2005	Here we report the cloning of PIG-V involved in transferring the second mannose in the GPI anchor.	Mannose	72-79	phosphatidylinositol glycan anchor biosynthesis class V	Sus scrofa	30-35
15632136-10	2005	We further found that the overexpression of hGPI7 decreased the level of PIG-O and, therefore, decreased the level of EtNP transferred to the third mannose.	Mannose	148-155	phosphatidylinositol glycan anchor biosynthesis class G	Homo sapiens	44-49
16851402-2	2005	Recently, it has been experimentally demonstrated that cyanovirin binds mannose oligomers on the surface of glycoprotein gp120.	Mannose	72-79	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	121-126
15536204-8	2005	Epinephrine increased mannose output from the perfused liver of fed rats, but this effect was negated in the presence of a glucose-6-phosphatase inhibitor.	Mannose	22-29	glucose-6-phosphatase catalytic subunit 1	Rattus norvegicus	123-144
15807994-1	2005	PAL is a glucose/mannose-specific lectin isolated from Pisum arvense seeds.	Mannose	17-24	leucine-rich repeat, Ig-like and transmembrane domains 1	Rattus norvegicus	0-3
15728497-6	2005	As shown by surface plasmon resonance spectroscopy, trimeric and tetrameric MBL bound to immobilized mannose-BSA and N-acetylglucosamine-BSA with comparable K(D) values (2.2 and 0.55 nM and 1.2 and 0.96 nM, respectively).	Mannose	101-108	mannose binding lectin 2	Homo sapiens	76-79
16233790-6	2005	Many macrophage cells strongly express mannose and mannose receptor-related receptors, and receptor-mediated gene transfer via the mannose receptor using a PV-Man glycopolymer is a versatile means of targeted gene delivery into these cells.	Mannose	39-46	mannose receptor C-type 1	Homo sapiens	131-147
15576633-4	2005	In contrast, hOAT4 synthesized in mutant CHO-Lec cells, carrying different structural forms of sugar moieties (mannose-rich in Lec1 cells, sialic acid-deficient in Lec2 cells, and sialic acid/galactose-deficient in Lec8 cells) were able to traffic to the cell surface.	Mannose	111-118	solute carrier family 22 member 11	Homo sapiens	13-18
15576633-7	2005	Processing of added oligosaccharides from mannose-rich type to complex type is important for enhancing the binding affinity of hOAT4 for its substrates.	Mannose	42-49	solute carrier family 22 member 11	Homo sapiens	127-132
15647440-0	2005	Association of mannose binding lectin (MBL) gene polymorphism and serum MBL concentration with characteristics and progression of systemic lupus erythematosus.	Mannose	15-22	mannose binding lectin 2	Homo sapiens	39-42
15545280-5	2005	Experiments with soluble molecules having the N-terminal two domains of human ICAMs identified glycans of the high mannose type N-linked to the second domain of the dendritic cell-specific ICAM-grabbing nonintegrin lectin-ligands ICAM-2 and ICAM-3.	Mannose	115-122	intercellular adhesion molecule 2	Homo sapiens	230-236
15545280-5	2005	Experiments with soluble molecules having the N-terminal two domains of human ICAMs identified glycans of the high mannose type N-linked to the second domain of the dendritic cell-specific ICAM-grabbing nonintegrin lectin-ligands ICAM-2 and ICAM-3.	Mannose	115-122	intercellular adhesion molecule 3	Homo sapiens	241-247
15545280-7	2005	High mannose glycans were absent in ICAM-1, which did not bind to the lectin, but they appeared in ICAM-1 mutants with additional N-linked glycosylation and lectin binding activity.	Mannose	5-12	intercellular adhesion molecule 1	Homo sapiens	36-42
15545280-7	2005	High mannose glycans were absent in ICAM-1, which did not bind to the lectin, but they appeared in ICAM-1 mutants with additional N-linked glycosylation and lectin binding activity.	Mannose	5-12	intercellular adhesion molecule 1	Homo sapiens	99-105
15647440-1	2005	OBJECTIVE: To determine whether occurrence, characteristics, and progression of systemic lupus erythematosus (SLE) are associated with polymorphism of the mannose binding lectin (MBL) gene and with serum MBL concentration.	Mannose	155-162	mannose binding lectin 2	Homo sapiens	179-182
15654820-9	2005	The interaction between the TSHR and CRD-Fc was calcium-dependent; it was inhibited by mannose (not galactose), and required a glycosylated TSHR A-subunit.	Mannose	87-94	thyroid stimulating hormone receptor	Homo sapiens	28-32
16164026-4	2005	mSIGNR1 has a similar specificity as human DC-SIGN for high mannose-containing ligands present on both cellular and pathogen ligands.	Mannose	60-67	CD209b antigen	Mus musculus	0-7
15714077-3	2005	Enzyme replacement therapy (ERT) with mannose-terminated glucocerebrosidase (imiglucerase, Cerezyme, Genzyme Corporation, Cambridge, MA) reverses or ameliorates many of the manifestations of type 1 Gaucher disease.	Mannose	38-45	glucosylceramidase beta	Homo sapiens	77-89
15607332-0	2005	SLC5A9/SGLT4, a new Na+-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose.	Mannose	87-94	solute carrier family 5 member 9	Homo sapiens	0-6
15607332-0	2005	SLC5A9/SGLT4, a new Na+-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose.	Mannose	87-94	solute carrier family 5 member 9	Homo sapiens	7-12
15488604-4	2005	Binding of MBL to HIV is dependent on the high-mannose glycans on gp120 while host cell glycans incorporated into virions do not contribute substantially to this interaction.	Mannose	47-54	mannose binding lectin 2	Homo sapiens	11-14
15681508-1	2005	The case history is presented of a woman with multiple respiratory infections and mannose binding lectin (MBL) deficiency but no evidence of bronchiectasis who developed a chronic Burkholderia multivorans infection.	Mannose	82-89	mannose binding lectin 2	Homo sapiens	106-109
15520001-0	2004	Excess mannose limits the growth of phosphomannose isomerase PMI40 deletion strain of Saccharomyces cerevisiae.	Mannose	7-14	mannose-6-phosphate isomerase PMI40	Saccharomyces cerevisiae S288C	61-66
15605233-6	2005	RESULTS: We found that lysozyme binds in a reversible manner to the Man beta(1-4) GlcNAc beta(1-4)GlcNAc moiety in the tri-mannosyl core structure of high mannose/hybrid and tri-antennary carbohydrate classes where GlcNAc is N-acetylglucosamine and Man is mannose.	Mannose	155-162	lysozyme	Homo sapiens	23-31
15605233-6	2005	RESULTS: We found that lysozyme binds in a reversible manner to the Man beta(1-4) GlcNAc beta(1-4)GlcNAc moiety in the tri-mannosyl core structure of high mannose/hybrid and tri-antennary carbohydrate classes where GlcNAc is N-acetylglucosamine and Man is mannose.	Mannose	256-263	lysozyme	Homo sapiens	23-31
15826378-1	2005	Small mannose-binding lectin (MBL)-associated protein (sMAP) is a component of the complex consisting of MBL and MBL-associated serine proteases (MASPs) in the lectin complement pathway.	Mannose	6-13	mannose-binding lectin (protein C) 2	Mus musculus	30-33
15826378-1	2005	Small mannose-binding lectin (MBL)-associated protein (sMAP) is a component of the complex consisting of MBL and MBL-associated serine proteases (MASPs) in the lectin complement pathway.	Mannose	6-13	RIKEN cDNA 1110004F10 gene	Mus musculus	55-59
15826378-1	2005	Small mannose-binding lectin (MBL)-associated protein (sMAP) is a component of the complex consisting of MBL and MBL-associated serine proteases (MASPs) in the lectin complement pathway.	Mannose	6-13	mannose-binding lectin (protein C) 2	Mus musculus	105-108
15826378-1	2005	Small mannose-binding lectin (MBL)-associated protein (sMAP) is a component of the complex consisting of MBL and MBL-associated serine proteases (MASPs) in the lectin complement pathway.	Mannose	6-13	mannose-binding lectin (protein C) 2	Mus musculus	105-108
15606100-4	2004	These compounds were designed to map onto biantennary sectors of high-mannose-type oligosaccharides carried by glycoprotein M6P/IGF2R ligands.	Mannose	70-77	insulin like growth factor 2 receptor	Homo sapiens	124-133
15452110-2	2004	This study investigated the role of lysosomal mannose 6-phosphorylated proteins in tumor necrosis factor (TNF)-induced apoptosis.	Mannose	46-53	tumor necrosis factor	Homo sapiens	83-104
15452110-2	2004	This study investigated the role of lysosomal mannose 6-phosphorylated proteins in tumor necrosis factor (TNF)-induced apoptosis.	Mannose	46-53	tumor necrosis factor	Homo sapiens	106-109
15452110-11	2004	These observations highlight the hitherto unrecognized role of some mannose 6-phosphorylated proteins such as tripeptidyl peptidase 1 in the apoptotic cascade triggered by TNF.	Mannose	68-75	tripeptidyl peptidase 1	Homo sapiens	110-133
15452110-11	2004	These observations highlight the hitherto unrecognized role of some mannose 6-phosphorylated proteins such as tripeptidyl peptidase 1 in the apoptotic cascade triggered by TNF.	Mannose	68-75	tumor necrosis factor	Homo sapiens	172-175
15447943-0	2004	Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2.	Mannose	4-11	toll-like receptor 2	Mus musculus	67-87
15522202-2	2004	WWS is due to defects in protein O-mannosyltransferase 1 (POMT1), which catalyzes the transfer of mannose to protein to form O-mannosyl glycans.	Mannose	98-105	protein O-mannosyltransferase 1	Homo sapiens	25-56
15452134-1	2004	GPI7 is involved in adding ethanolaminephosphate to the second mannose in the biosynthesis of glycosylphosphatidylinositol (GPI) in Saccharomyces cerevisiae.	Mannose	63-70	mannose-ethanolamine phosphotransferase LAS21	Saccharomyces cerevisiae S288C	0-4
15522202-2	2004	WWS is due to defects in protein O-mannosyltransferase 1 (POMT1), which catalyzes the transfer of mannose to protein to form O-mannosyl glycans.	Mannose	98-105	protein O-mannosyltransferase 1	Homo sapiens	58-63
15544801-5	2004	However, we demonstrated recently that the molecular recognition of ManLAM terminal mannose units by human pulmonary surfactant protein A (hSP-A) carbohydrate recognition domains depends on the presence of the lipid moiety of the ManLAMs as proposed by Sidobre et al.	Mannose	84-91	surfactant protein A1	Homo sapiens	107-137
15548047-2	2004	Mannose-modified SPG can also wrap PANIs to give nanofibers having a lectin affinity.	Mannose	0-7	SPG16	Homo sapiens	17-20
15483660-1	2004	The mannose-binding lectin MBL2 plays an important role in the innate immune system.	Mannose	4-11	mannose binding lectin 2	Homo sapiens	27-31
15351237-1	2004	Mannose-binding C-type lectin (MBL) is an important component of innate immunity in mammals.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	31-34
15494315-0	2004	Glucose and sucrose act as agonist and mannose as antagonist ligands of the G protein-coupled receptor Gpr1 in the yeast Saccharomyces cerevisiae.	Mannose	39-46	Gpr1p	Saccharomyces cerevisiae S288C	103-107
15381182-0	2004	Mannose binding lectin enhances IL-1beta and IL-10 induction by non-lipopolysaccharide (LPS) components of Neisseria meningitidis.	Mannose	0-7	interleukin 1 beta	Homo sapiens	32-40
15381182-1	2004	Mannose binding lectin (MBL) is a key molecule in the lectin pathway of complement activation, and likely of importance in our innate defence against meningococcal infection.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
15271988-6	2004	dPOMT2 transferred a mannose to the dystroglycan protein only when it was coexpressed with dPOMT1.	Mannose	21-28	twisted	Drosophila melanogaster	0-6
15271988-6	2004	dPOMT2 transferred a mannose to the dystroglycan protein only when it was coexpressed with dPOMT1.	Mannose	21-28	rotated abdomen	Drosophila melanogaster	91-97
15351237-2	2004	Mannose-binding lectin (MBL), an acute phase protein, acts as an opsonin for phagocytosis and also activates the mannan-binding lectin complement pathway.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
15367629-9	2004	The nature of these mutations was entirely different from that of mutations that are known to appear in HIV-1 gp120 under the pressure of other viral entry inhibitors such as dextran sulfate, bicyclams (i.e., AMD3100), and chicoric acid, which also explains the lack of cross-resistance of plant lectin-resistant viruses to any other HIV inhibitor including T-20 and the blue-green algae (cyanobacteria)-derived mannose-specific cyanovirin.	Mannose	412-419	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	110-115
15450746-5	2004	Secretory IgA glycans bind gut bacteria, and an unusual cluster of mannose residues on gp120, the surface coat protein of the HIV virus, is recognized by the novel "domain-swapped" IgG 2G12 serum antibody.	Mannose	67-74	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	87-92
15470093-2	2004	Assembly of Saccharomyces cerevisiae GPIs includes the addition of a fourth, side-branching mannose (Man) to the third Man of the core GPI glycan by the Smp3 mannosyltransferase.	Mannose	92-99	glucose-6-phosphate isomerase	Homo sapiens	37-40
15470093-2	2004	Assembly of Saccharomyces cerevisiae GPIs includes the addition of a fourth, side-branching mannose (Man) to the third Man of the core GPI glycan by the Smp3 mannosyltransferase.	Mannose	92-99	phosphatidylinositol glycan anchor biosynthesis class Z	Homo sapiens	153-177
15470093-6	2004	Repression of CaSMP3 expression leads to accumulation of a GPI precursor glycolipid whose glycan headgroup contains three mannoses and bears a phosphodiester-linked substituent on its first Man.	Mannose	122-130	glucose-6-phosphate isomerase	Homo sapiens	59-62
15208306-0	2004	Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo.	Mannose	26-33	glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase	Saccharomyces cerevisiae S288C	6-11
15208306-8	2004	Our data indicate that hSmp3p functions as a mannosyltransferase that adds a fourth mannose to certain Man(3)-GPIs during biosynthesis of the human GPI precursor, and suggest it may do so in a tissue-specific manner.	Mannose	84-91	phosphatidylinositol glycan anchor biosynthesis class Z	Homo sapiens	23-29
15377434-5	2004	RESULTS: DC-SIGN, a dendritic cell-specific adhesion receptor and a type II transmembrane mannose-binding C-type lectin, is very important in the function of dendritic cells (DC), both in mediating naive T cell interactions through ICAM-3 and as a rolling receptor that mediates the DC-specific ICAM-2-dependent migration processes.	Mannose	90-97	intercellular adhesion molecule 3	Homo sapiens	232-238
15377434-5	2004	RESULTS: DC-SIGN, a dendritic cell-specific adhesion receptor and a type II transmembrane mannose-binding C-type lectin, is very important in the function of dendritic cells (DC), both in mediating naive T cell interactions through ICAM-3 and as a rolling receptor that mediates the DC-specific ICAM-2-dependent migration processes.	Mannose	90-97	intercellular adhesion molecule 2	Homo sapiens	295-301
15117936-4	2004	The MBP was isolated by chromatography on the mannose affinity gel.	Mannose	46-53	myelin basic protein	Homo sapiens	4-7
15243942-1	2004	Mannose-binding lectin (MBL) is a serum collectin believed to be of importance in innate immunity.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
15150274-5	2004	Carbohydrate content analysis revealed that complex type-specific Golgi apparatus (GA) oligosaccharides were present on pig Duox2-Q686X, whereas human truncated Duox2 carried only high mannose-type sugar chains characteristic of the ER.	Mannose	185-192	dual oxidase 2	Homo sapiens	161-166
15294975-7	2004	ERAD-mediated degradation of the mutant p41 is dependent on mannose trimming and inhibition of mannosidase I stabilizes Ii.	Mannose	60-67	mitogen-activated protein kinase 1	Homo sapiens	40-43
15070860-0	2004	The binding of VIP36 and alpha-amylase in the secretory vesicles via high-mannose type glycans.	Mannose	74-81	lectin, mannose-binding 2	Rattus norvegicus	15-20
15070860-1	2004	Vesicular integral protein of 36 kDa (VIP36) is an intracellular lectin recognizing high-mannose type glycans and is highly expressed in salivary glands, especially the parotid gland, which secretes alpha-amylase in large quantities.	Mannose	89-96	lectin, mannose-binding 2	Rattus norvegicus	0-36
15070860-1	2004	Vesicular integral protein of 36 kDa (VIP36) is an intracellular lectin recognizing high-mannose type glycans and is highly expressed in salivary glands, especially the parotid gland, which secretes alpha-amylase in large quantities.	Mannose	89-96	lectin, mannose-binding 2	Rattus norvegicus	38-43
15236335-3	2004	Among the carbohydrates and glycoproteins tested, D-mannose, fucoidan, dextran sulfate, and fibronectin were the most potent inhibitors of oocyte penetration (90% or more inhibition), while L-fucose and vitronectin inhibited the penetration rate to a lesser extent (around 50% inhibition).	Mannose	50-59	vitronectin	Bos taurus	203-214
15117936-8	2004	recombinant MBP possesses mannose binding activity, and (ii).	Mannose	26-33	myelin basic protein	Homo sapiens	12-15
15044389-5	2004	Using the osteosarcoma-derived MHH-ES1 cell line we successfully expressed a recombinant BM-40 that bears at least in part the bone-specific high-mannose N-glycosylation in addition to complex type and hybrid structures.	Mannose	146-153	secreted protein acidic and cysteine rich	Homo sapiens	89-94
15296462-5	2004	A33 antigen naturally expressed in the SW1222 human colon cancer cell line (A33) also possessed a high abundance of high mannose glycans (72%).	Mannose	121-128	glycoprotein A33	Homo sapiens	0-3
15296462-5	2004	A33 antigen naturally expressed in the SW1222 human colon cancer cell line (A33) also possessed a high abundance of high mannose glycans (72%).	Mannose	121-128	glycoprotein A33	Homo sapiens	76-79
15044389-8	2004	BM-40 carrying high-mannose structures binds collagen I with higher affinity, suggesting that differentially glycosylated forms may have different functional roles in vivo.	Mannose	20-27	secreted protein acidic and cysteine rich	Homo sapiens	0-5
15161239-2	2004	The glycosylation cystatin (glycocystatin) contained a polysaccharide chain that was composed of 50 DP of mannose residues.	Mannose	106-113	cystatin C	Gallus gallus	18-26
15130779-1	2004	N-Acetylglucosaminyltransferase (GnT)-III catalyzes the attachment of an N-acetylglucosamine (GlcNAc) residue to mannose in beta(1-4) configuration in the region of N-glycans and forms a bisecting GlcNAc.	Mannose	113-120	mannoside acetylglucosaminyltransferase 3	Mus musculus	0-41
15148380-8	2004	Galectin-15 protein was functional in binding lactose and mannose sugars and immunologically identical to the unnamed Mr 14,000 (14K) protein from the ovine uterus that forms crystalline inclusion bodies in endometrial epithelia and conceptus Tr.	Mannose	58-65	galectin 15	Ovis aries	0-11
14973265-12	2004	In conclusion, the binding of glycodelin-A to sperm involves mannose, fucose, and possibly E- selectin residues, while that of glycodelin-F involves mannose, fucose, and N-acetylglucosamine but not the selectin residue.	Mannose	61-68	progestagen associated endometrial protein	Homo sapiens	30-42
15033941-5	2004	The Glut2 transporter inhibitors phloretin and cytochalasin B added following 30-min mannose uptake reduced the previously accumulated D-mannose, whereas these two agents increased the cell to external medium 3-O-methyl-glucose (3-OMG) concentration ratio.	Mannose	85-92	solute carrier family 2 member 2	Gallus gallus	4-9
15033941-5	2004	The Glut2 transporter inhibitors phloretin and cytochalasin B added following 30-min mannose uptake reduced the previously accumulated D-mannose, whereas these two agents increased the cell to external medium 3-O-methyl-glucose (3-OMG) concentration ratio.	Mannose	135-144	solute carrier family 2 member 2	Gallus gallus	4-9
15136555-6	2004	The dominant specificities found for SIGN-R1 and SIGN-R3 are mannose- and fucose-related, as expressed on high mannose type N-glycans and Lewis(a/b)/Lewis(x/y)-type sequences, respectively, with subtle differences between the receptors.	Mannose	61-68	CD209b antigen	Mus musculus	37-44
15136555-6	2004	The dominant specificities found for SIGN-R1 and SIGN-R3 are mannose- and fucose-related, as expressed on high mannose type N-glycans and Lewis(a/b)/Lewis(x/y)-type sequences, respectively, with subtle differences between the receptors.	Mannose	61-68	CD209d antigen	Mus musculus	49-56
15136555-6	2004	The dominant specificities found for SIGN-R1 and SIGN-R3 are mannose- and fucose-related, as expressed on high mannose type N-glycans and Lewis(a/b)/Lewis(x/y)-type sequences, respectively, with subtle differences between the receptors.	Mannose	111-118	CD209b antigen	Mus musculus	37-44
15136555-6	2004	The dominant specificities found for SIGN-R1 and SIGN-R3 are mannose- and fucose-related, as expressed on high mannose type N-glycans and Lewis(a/b)/Lewis(x/y)-type sequences, respectively, with subtle differences between the receptors.	Mannose	111-118	CD209d antigen	Mus musculus	49-56
14985347-7	2004	Various models trying to explain how Gpi7p, a plasma membrane protein, directs the addition of ethanolamine phosphate to mannose 2 of the GPI core have been formulated and put to the test.	Mannose	121-128	mannose-ethanolamine phosphotransferase LAS21	Saccharomyces cerevisiae S288C	37-42
14985347-2	2004	Here we confirm that the ethanolamine phosphate side chain added by Mcd4p to the first mannose is a prerequisite for the addition of the third mannose to the GPI precursor lipid and demonstrate that, contrary to an earlier report, an ethanolamine phosphate can equally be found on the majority of yeast GPI protein anchors.	Mannose	87-94	mannose-ethanolamine phosphotransferase MCD4	Saccharomyces cerevisiae S288C	68-73
14985347-2	2004	Here we confirm that the ethanolamine phosphate side chain added by Mcd4p to the first mannose is a prerequisite for the addition of the third mannose to the GPI precursor lipid and demonstrate that, contrary to an earlier report, an ethanolamine phosphate can equally be found on the majority of yeast GPI protein anchors.	Mannose	143-150	mannose-ethanolamine phosphotransferase MCD4	Saccharomyces cerevisiae S288C	68-73
15148336-3	2004	The mannose-binding lectin (MBL, also known as mannose-binding protein) is an oligomeric serum molecule that recognizes carbohydrates decorating a broad range of infectious agents including S. aureus.	Mannose	4-11	mannose-binding lectin (protein C) 2	Mus musculus	28-31
15128528-5	2004	Phosphoenolpyruvate:mannose phosphotransferase system (PTS) components of mannose PTS, including the phosphocarrier protein HPr and EII(Man), were lacking in ethanol-adapted cells, providing strong evidence that mannose PTS is absent in ethanol-adapted cells, and this represents a metabolic advantage to O. oeni cells during malolactic fermentation.	Mannose	20-27	haptoglobin-related protein	Homo sapiens	124-127
15128528-5	2004	Phosphoenolpyruvate:mannose phosphotransferase system (PTS) components of mannose PTS, including the phosphocarrier protein HPr and EII(Man), were lacking in ethanol-adapted cells, providing strong evidence that mannose PTS is absent in ethanol-adapted cells, and this represents a metabolic advantage to O. oeni cells during malolactic fermentation.	Mannose	74-81	haptoglobin-related protein	Homo sapiens	124-127
14748740-4	2004	In the present study, we show that the 145 kDa form of GC-C contains sialic acid and galactose residues and is present on the PM (plasma membrane) of cells, whereas the 130 kDa form is a high mannose form that is resident in the endoplasmic reticulum and serves as the precursor for the PM-associated form.	Mannose	192-199	natriuretic peptide receptor 3	Homo sapiens	55-59
15112051-8	2004	Moreover, properly folded glycoproteins with mannose-trimmed glycans can be deglucosylated in the Golgi by endomannosidase, thereby releasing calreticulin and permitting formation of complex OS.	Mannose	45-52	mannosidase endo-alpha	Homo sapiens	107-122
14726380-4	2004	FVIII expression is limited by unstable mRNA, interaction with endoplasmic reticulum (ER) chaperones, and a requirement for facilitated ER to Golgi transport through interaction with the mannose-binding lectin LMAN1.	Mannose	187-194	coagulation factor VIII	Homo sapiens	0-5
14726380-4	2004	FVIII expression is limited by unstable mRNA, interaction with endoplasmic reticulum (ER) chaperones, and a requirement for facilitated ER to Golgi transport through interaction with the mannose-binding lectin LMAN1.	Mannose	187-194	lectin, mannose binding 1	Homo sapiens	210-215
15112051-8	2004	Moreover, properly folded glycoproteins with mannose-trimmed glycans can be deglucosylated in the Golgi by endomannosidase, thereby releasing calreticulin and permitting formation of complex OS.	Mannose	45-52	calreticulin	Homo sapiens	142-154
14752117-8	2004	The C1" of the modeled donor mannose is within hydrogen-bonding distance of both the hydroxyl of Tyr(220) and the O2 of the acceptor mannose.	Mannose	29-36	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	4-7
15100290-5	2004	Also, when another carbohydrate was present in CDR1, CDR2, or CDR3 of the L chain, the V(H) CDR2 glycan remained high mannose.	Mannose	118-125	cerebellar degeneration related protein 1	Homo sapiens	47-51
15100290-5	2004	Also, when another carbohydrate was present in CDR1, CDR2, or CDR3 of the L chain, the V(H) CDR2 glycan remained high mannose.	Mannose	118-125	CDR3	Homo sapiens	62-66
14711836-6	2004	LSECtin binds to mannose, GlcNAc, and fucose in a Ca(2+)-dependent manner but not to galactose.	Mannose	17-24	C-type lectin domain family 4 member G	Homo sapiens	0-7
14970226-6	2004	Monosaccharides with equatorial 4-OH groups competed as well as D-mannose for gp120 binding to DC-SIGN, regardless of how the other hydroxyl groups were positioned.	Mannose	64-73	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	78-83
14752117-8	2004	The C1" of the modeled donor mannose is within hydrogen-bonding distance of both the hydroxyl of Tyr(220) and the O2 of the acceptor mannose.	Mannose	133-140	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	4-7
15078900-8	2004	Additional studies using immature monocyte-derived dendritic cells demonstrated that although mannose-binding C-type lectin receptors and CD4 are the principal receptors for gp120, other mechanisms may account for virus capture.	Mannose	94-101	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	174-179
14966117-5	2004	Disruption of FPS1, the aquaglyceroporin gene, reduced glucose-independent uptake by only about 25%, and the residual uptake was nearly completely inhibited by hexoses, including glucose, galactose, mannose, and fructose but not pentoses or disaccharides.	Mannose	199-206	Fps1p	Saccharomyces cerevisiae S288C	14-18
14718532-4	2004	Here we report efficient binding of purified ERGIC-53 to immobilized mannose at pH 7.4, the pH of the ER, but not at slightly lower pH.	Mannose	69-76	lectin, mannose binding 1	Homo sapiens	45-53
15021250-6	2004	In addition, the clinical variability of patients with mutations in the genes encoding fukutin, protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase 1 and the fukutin-related protein has been significantly expanded.	Mannose	113-120	fukutin related protein	Homo sapiens	171-194
14640982-5	2004	The rate of N-glycan conversion from high-mannose into complex form in a glycosylation mutant (N555) of AE1 C843A, and thus the rate of trafficking from the endoplasmic reticulum to the Golgi, were comparable with that of AE1 (N555).	Mannose	42-49	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	104-107
15003531-0	2004	Actinohivin, a novel anti-human immunodeficiency virus protein from an actinomycete, inhibits viral entry to cells by binding high-mannose type sugar chains of gp120.	Mannose	131-138	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	160-165
15003531-8	2004	The above results indicate that high-mannose type saccharide chains of gp120 are molecular targets of AH in its anti-HIV activity.	Mannose	37-44	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	71-76
14640982-5	2004	The rate of N-glycan conversion from high-mannose into complex form in a glycosylation mutant (N555) of AE1 C843A, and thus the rate of trafficking from the endoplasmic reticulum to the Golgi, were comparable with that of AE1 (N555).	Mannose	42-49	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	222-225
14978109-3	2004	As a consequence of this binding, specific functional inhibition of the classical pathway and impaired mannan-binding lectin to mannose were observed.	Mannose	128-135	mannose binding lectin 2	Homo sapiens	103-124
15004183-1	2004	Human mannose-binding lectin (MBL) provides a first line of defense against microorganisms by complement activation and/or opsonization in the absence of specific Ab.	Mannose	6-13	mannose binding lectin 2	Homo sapiens	30-33
14693913-7	2004	Using hBSSL as a platform to study Pichia"s O-glycosylation capabilities, we found that nearly all of these sites were occupied by mannose-containing O-glycans, whose structures, after beta-elimination and purification, were assigned by (1)H NMR and, in some cases, by linkage-specific exoglycosidases and methylation analysis.	Mannose	131-138	carboxyl ester lipase	Homo sapiens	6-11
15009185-6	2004	Sugar binding assays revealed that N-acetyl-lactosamine, mannose and N-acetyl-glucosamine residues widely expressed in human placenta had the strongest binding affinity to both the purified and recombinant PP13/galectin-13, which also effectively agglutinated erythrocytes.	Mannose	57-64	galectin 13	Homo sapiens	206-210
15009185-6	2004	Sugar binding assays revealed that N-acetyl-lactosamine, mannose and N-acetyl-glucosamine residues widely expressed in human placenta had the strongest binding affinity to both the purified and recombinant PP13/galectin-13, which also effectively agglutinated erythrocytes.	Mannose	57-64	galectin 13	Homo sapiens	211-222
14709599-7	2004	The accumulation pattern suggested a deficiency of the ALG1 beta1,4 mannosyltransferase, which adds the first mannose residue to lipid-linked oligosaccharides.	Mannose	110-117	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	55-59
14610228-1	2004	Enzyme replacement therapy for Gaucher disease uses a recombinant glucocerebrosidase (Cerezyme) whose oligosaccharide chains have been remodeled to expose the core mannose residues.	Mannose	164-171	glucosylceramidase beta	Rattus norvegicus	66-84
15086552-2	2004	Langerin/CD207 is a mannose-binding C-type lectin that is specifically expressed by LC.	Mannose	20-27	CD207 antigen	Mus musculus	0-8
15086552-2	2004	Langerin/CD207 is a mannose-binding C-type lectin that is specifically expressed by LC.	Mannose	20-27	CD207 antigen	Mus musculus	9-14
15144709-2	2004	MBL can bind to glycoproteins terminated with mannose and N-acetylglucosamine present in the cell walls on a variety of microorganisms.	Mannose	46-53	mannose binding lectin 2	Homo sapiens	0-3
14707091-3	2004	In this study, we have studied the mannose-binding potential of murine Mphi and identified the dendritic cell-specific ICAM-3-grabbing nonintegrin homolog, SIGN-related 1 (SIGNR1), as a major MR on murine resident peritoneal Mphi.	Mannose	35-42	CD209b antigen	Mus musculus	172-178
14617637-2	2004	It has been demonstrated that the transfer of GlcNAc to the 2-OH position of the mannose residue is catalyzed by the enzyme, protein O-mannose beta1,2-N-acetylglucosaminyltransferase (POMGnT1), but the enzymatic basis of the transfer to the 6-OH position is unknown.	Mannose	81-88	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)	Homo sapiens	184-191
14705935-8	2004	The mutation of residues from the primary binding site of CRT, i.e., those interacting with glucose, appears to be far less tolerated as compared to mutations in residues that interact with the mannose residues of the glycan.	Mannose	194-201	calreticulin	Homo sapiens	58-61
14570881-0	2004	Variation of high mannose chains of Tamm-Horsfall glycoprotein confers differential binding to type 1-fimbriated Escherichia coli.	Mannose	18-25	uromodulin	Homo sapiens	36-62
14570881-2	2004	Recent experimental evidence indicates that the defensive capability of THP relies on its single high mannose chain, which binds to E. coli FimH lectin and competes with mannosylated uroplakin receptors on the bladder surface.	Mannose	102-109	uromodulin	Homo sapiens	72-75
14570881-10	2004	These results demonstrate for the first time that the species variations of the glycomoiety of THP can lead to the differential binding of THP to type 1-fimbriated E. coli and that the differences in high mannose processing may reflect species-specific adaptation of urinary defenses against E. coli infections.	Mannose	205-212	uromodulin	Homo sapiens	95-98
14570881-10	2004	These results demonstrate for the first time that the species variations of the glycomoiety of THP can lead to the differential binding of THP to type 1-fimbriated E. coli and that the differences in high mannose processing may reflect species-specific adaptation of urinary defenses against E. coli infections.	Mannose	205-212	uromodulin	Homo sapiens	139-142
15316281-9	2004	N-cadherin from WM35 (primary tumor site) possessed high-mannose and biantennary complex type glycans with alpha2-6 linked sialic acid.	Mannose	57-64	cadherin 2	Homo sapiens	0-10
14711620-3	2004	Certain sugars, including glucose, fructose, and mannose, repress the promoter of JEN1, which encodes a lactate-pyruvate transporter, in a dose-dependent manner.	Mannose	49-56	Jen1p	Saccharomyces cerevisiae S288C	82-86
15113002-2	2004	Previous mutational analysis suggested that 2G12 recognized a novel cluster of high-mannose type oligosaccharides on HIV-1 gp120.	Mannose	84-91	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	123-128
15467395-4	2004	We have found that IL-2 recognizes a high-mannose type glycan on the alpha subunit of the IL-2 receptor as well as a peptide portion of this subunit.	Mannose	42-49	interleukin 2	Homo sapiens	19-23
15467395-4	2004	We have found that IL-2 recognizes a high-mannose type glycan on the alpha subunit of the IL-2 receptor as well as a peptide portion of this subunit.	Mannose	42-49	interleukin 2	Homo sapiens	90-94
15352424-1	2004	Deficiency of mannose binding lectin (MBL), a C-type lectin with structural similarities to C1q, has been shown to predispose to the development of systemic lupus erythematosus (SLE).	Mannose	14-21	mannose binding lectin 2	Homo sapiens	38-41
15352424-1	2004	Deficiency of mannose binding lectin (MBL), a C-type lectin with structural similarities to C1q, has been shown to predispose to the development of systemic lupus erythematosus (SLE).	Mannose	14-21	complement C1q A chain	Homo sapiens	92-95
14687936-4	2004	Competition with D-mannose and with antibodies directed against the lectin binding site of MBL indicate that the 60 kDa form represents an intracellular association of MBL through its lectin moiety.	Mannose	17-26	mannose binding lectin 2	Homo sapiens	168-171
12887296-1	2003	Mannose- or mannan-binding lectin (MBL) is a member of the collectin protein family, which includes lung surfactant proteins SP-A and SP-D.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	12-33
14744025-1	2003	beta-D-Mannoside beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) catalyses the attachment of an N-acetylglucosamine (GlcNAc) residue to mannose in the beta(1-4) configuration in N-glycans, and forms a bisecting GlcNAc.	Mannose	143-150	mannoside acetylglucosaminyltransferase 3	Mus musculus	63-70
14744025-1	2003	beta-D-Mannoside beta-1,4-N-acetylglucosaminyltransferase III (GnT-III) catalyses the attachment of an N-acetylglucosamine (GlcNAc) residue to mannose in the beta(1-4) configuration in N-glycans, and forms a bisecting GlcNAc.	Mannose	143-150	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9	Mus musculus	158-166
14697291-2	2003	C1 inhibitor (C1 Inh) inhibits the earliest steps of the classical and the mannose binding lectin pathways.	Mannose	75-82	serine (or cysteine) peptidase inhibitor, clade G, member 1	Mus musculus	0-12
14697291-2	2003	C1 inhibitor (C1 Inh) inhibits the earliest steps of the classical and the mannose binding lectin pathways.	Mannose	75-82	serine (or cysteine) peptidase inhibitor, clade G, member 1	Mus musculus	14-20
15082929-12	2003	These data and the current knowledge about the identity of genes mutated in the vtc lines suggest that an alternative pathway is present in plants, which can bypass the deficiency of GDP-mannose production of the vtc1-1 mutant and possibly circumvent other steps in the D-mannose pathway to synthesize vitamin C.	Mannose	270-279	Glucose-1-phosphate adenylyltransferase family protein	Arabidopsis thaliana	213-219
14581539-1	2003	C-type lectins such as DC-SIGN and L-SIGN, which bind mannose-enriched carbohydrate modifications of host and pathogen proteins, have been shown to bind glycoproteins of several viruses and facilitate either cis or trans infection.	Mannose	54-61	CD209 molecule	Homo sapiens	23-30
14581539-1	2003	C-type lectins such as DC-SIGN and L-SIGN, which bind mannose-enriched carbohydrate modifications of host and pathogen proteins, have been shown to bind glycoproteins of several viruses and facilitate either cis or trans infection.	Mannose	54-61	C-type lectin domain family 4 member M	Homo sapiens	35-41
14568388-4	2003	MBL binds to a range of sugars including N-acetyl-D-glucosamine, mannose, N-acetyl-mannosamine, fucose and glucose.	Mannose	65-72	mannose binding lectin 2	Homo sapiens	0-3
12812916-8	2003	MAP17 is responsible for mannose transport expression in oocytes by rat kidney cortex mRNA.	Mannose	25-32	PDZK1 interacting protein 1	Rattus norvegicus	0-5
12847103-5	2003	Measurements of the incorporation of radioactive mannose into ricin sulf-2 showed that ricin reached the ER in cells depleted of epsilon-COP.	Mannose	49-56	extracellular sulfatase Sulf-2	Cricetulus griseus	68-74
12957931-11	2003	We propose that in S. thermophilus, the general and specific glucose/mannose PTS proteins are not involved in glucose transport but might have regulatory functions associated with the phosphotransfer properties of HPr and IIAB(Man).	Mannose	69-76	haptoglobin-related protein	Homo sapiens	214-217
12933871-1	2003	Variant alleles in the mannose-binding lectin (MBL) gene (mbl2) causing low levels of functional MBL are associated with susceptibility to different infections and are common in areas where malaria is endemic.	Mannose	23-30	mannose binding lectin 2	Homo sapiens	47-50
12933871-1	2003	Variant alleles in the mannose-binding lectin (MBL) gene (mbl2) causing low levels of functional MBL are associated with susceptibility to different infections and are common in areas where malaria is endemic.	Mannose	23-30	mannose binding lectin 2	Homo sapiens	97-100
12933871-5	2003	Distinct calcium-dependent binding of MBL to the membrane of P. falciparum-infected erythrocytes, which could be inhibited by mannose, was observed.	Mannose	126-133	mannose binding lectin 2	Homo sapiens	38-41
15180092-11	2004	The third study shows that low serum levels of the complement-activating serum lectin, mannan (mannose) binding protein (lectin) (MBP = MBL), are associated with a higher erythrocyte sedimentation rate (ESR) (p=0.006), joint swelling score (JS score) (p=0.019), limitation of joint motion score (LM score) (p=0.027), and annual increase in radiographic destruction score (R score) (p=0.053).	Mannose	95-102	myelin basic protein	Homo sapiens	130-133
15180092-11	2004	The third study shows that low serum levels of the complement-activating serum lectin, mannan (mannose) binding protein (lectin) (MBP = MBL), are associated with a higher erythrocyte sedimentation rate (ESR) (p=0.006), joint swelling score (JS score) (p=0.019), limitation of joint motion score (LM score) (p=0.027), and annual increase in radiographic destruction score (R score) (p=0.053).	Mannose	95-102	mannose binding lectin 2	Homo sapiens	136-139
14685143-8	2003	RESULTS: Outer segment membranes of RPE-deprived retinas exposed to lactose were significantly more organized than both control RPE-deprived retinas and those exposed to mannose.	Mannose	170-177	ribulose-5-phosphate-3-epimerase S homeolog	Xenopus laevis	36-39
14629470-5	2003	The interaction was mediated via high mannose-containing asparagine-linked oligosaccharides that are densely situated within the B domain of FVIII, as well as protein-protein interactions.	Mannose	38-45	coagulation factor VIII	Homo sapiens	141-146
12913002-5	2003	The interdomain carbohydrate recognition domain-neck angle is significantly less in SP-A than in the homologous collectins, surfactant protein D, and mannose-binding protein.	Mannose	150-157	surfactant protein A1	Homo sapiens	84-88
12941144-3	2003	We investigated the possibility that mannose-binding lectin (MBL), a soluble lectin that functions as a recognition molecule in innate immunity and that binds to HIV, could block trans infection mediated by DC-SIGN.	Mannose	37-44	mannose binding lectin 2	Homo sapiens	61-64
12887296-1	2003	Mannose- or mannan-binding lectin (MBL) is a member of the collectin protein family, which includes lung surfactant proteins SP-A and SP-D.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	35-38
12887296-1	2003	Mannose- or mannan-binding lectin (MBL) is a member of the collectin protein family, which includes lung surfactant proteins SP-A and SP-D.	Mannose	0-7	surfactant protein A1	Homo sapiens	125-129
12887296-1	2003	Mannose- or mannan-binding lectin (MBL) is a member of the collectin protein family, which includes lung surfactant proteins SP-A and SP-D.	Mannose	0-7	surfactant protein D	Homo sapiens	134-138
12832074-4	2003	Surface-expressed E2 contained trans-Golgi modified complex/hybrid type carbohydrate and migrated diffusely between 70 and 90 kDa while intracellular E1 and E2 existed as high mannose 35 kDa and 70 kDa precursors, respectively.	Mannose	176-183	small nucleolar RNA, H/ACA box 73A	Homo sapiens	150-159
12672701-2	2003	A critical step in the biosynthetic pathway leading from high mannose to these complex structures includes the transfer of N-acetylglucosamine (GlcNAc) to a mannose residue by the inverting N-acetylglucosaminyltransferase I (GnT-I).	Mannose	62-69	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	225-230
12672701-2	2003	A critical step in the biosynthetic pathway leading from high mannose to these complex structures includes the transfer of N-acetylglucosamine (GlcNAc) to a mannose residue by the inverting N-acetylglucosaminyltransferase I (GnT-I).	Mannose	157-164	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	225-230
12734200-6	2003	CA125 is also N-glycosylated, expressing primarily high mannose and complex bisecting type N-linked glycans.	Mannose	56-63	mucin 16, cell surface associated	Homo sapiens	0-5
12831843-3	2003	Previously, we demonstrated that a hexose (mannose) and two amino sugars (N-acetylglucosamine and N-acetylgalactosamine), when covalently conjugated to bovine serum albumin (BSA) (functional neoglycoproteins, ngps), mimicked mZP3 and induced the AR [Biol.	Mannose	43-50	albumin	Mus musculus	159-178
12831843-3	2003	Previously, we demonstrated that a hexose (mannose) and two amino sugars (N-acetylglucosamine and N-acetylgalactosamine), when covalently conjugated to bovine serum albumin (BSA) (functional neoglycoproteins, ngps), mimicked mZP3 and induced the AR [Biol.	Mannose	43-50	zona pellucida glycoprotein 3	Mus musculus	225-229
12853121-8	2003	Functional studies showed that degraded SP-D had lost its calcium-dependent lectin properties, i.e. neither bound to mannose nor agglutinated bacteria.	Mannose	117-124	surfactant protein D	Homo sapiens	40-44
12736254-4	2003	We also show that misfolded alpha1-antitrypsin NHK contains labeled Glc1Man9GlcNAc and Man5-9GlcNAc released by endo-beta-N-acetylglucosaminidase H in pulse-chase experiments with [2-3H]mannose.	Mannose	186-193	serpin family A member 1	Homo sapiens	28-46
12626394-5	2003	The langerin CRD shows specificity for mannose, GlcNAc, and fucose, but only the trimeric extracellular domain fragment binds to glycoprotein ligands.	Mannose	39-46	CD207 molecule	Homo sapiens	4-12
12778468-7	2003	CpG-ODN treatment resulted in reduced levels of IL-4, but increased levels of IFN-gamma, IL-12 and inducible NO synthase in infected spleen cells, which was magnified by encapsulation in mannose-coated liposomes.	Mannose	187-194	interferon gamma	Mus musculus	78-87
12626400-5	2003	Previous studies have shown that DC-SIGN binds HIV gp120 that contains high-mannose-type N-glycans.	Mannose	76-83	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	51-56
12770793-2	2003	Polymorphism of codon 54 of the mannose binding lectin (MBL) gene, whose presence of the minority allele leads to significant reduction of serum MBL concentration, was investigated in 128 Japanese patients with type I diabetes and 78 healthy volunteers by restriction fragment length polymorphism method.	Mannose	32-39	mannose binding lectin 2	Homo sapiens	56-59
12770793-2	2003	Polymorphism of codon 54 of the mannose binding lectin (MBL) gene, whose presence of the minority allele leads to significant reduction of serum MBL concentration, was investigated in 128 Japanese patients with type I diabetes and 78 healthy volunteers by restriction fragment length polymorphism method.	Mannose	32-39	mannose binding lectin 2	Homo sapiens	145-148
12717434-2	2003	LMAN1 is a mannose-binding type 1 transmembrane protein localized to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC; refs.	Mannose	11-18	lectin, mannose binding 1	Homo sapiens	0-5
12626394-6	2003	Langerin extracellular domain binds mammalian high mannose oligosaccharides, as well mannose-containing structures on yeast invertase but does not bind complex glycan structures.	Mannose	51-58	CD207 molecule	Homo sapiens	0-8
12595462-4	2003	by a mycobacterial cell wall lipoglycan known as mannose-capped lipoarabinomannan (ManLAM) in mouse macrophages costimulated with gamma interferon (IFN-gamma).	Mannose	49-56	interferon gamma	Mus musculus	130-157
12707349-0	2003	Origin of mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 involved in the lectin complement pathway traced back to the invertebrate, amphioxus.	Mannose	10-17	MBL associated serine protease 1	Homo sapiens	61-65
12653690-2	2003	DC-SIGN (dendritic cell-specific ICAM-grabbing non-integrin, where ICAM is intercellular adhesion molecule) is a recently described mannose-specific C-type lectin expressed by dendritic cells.	Mannose	132-139	CD209 molecule	Homo sapiens	0-7
12653690-2	2003	DC-SIGN (dendritic cell-specific ICAM-grabbing non-integrin, where ICAM is intercellular adhesion molecule) is a recently described mannose-specific C-type lectin expressed by dendritic cells.	Mannose	132-139	CD209 molecule	Homo sapiens	9-59
12713659-3	2003	Similarly to inhibitors of alpha-mannosidases, geldanamycin stabilized a high mannose PrPC glycoform and prevented the subsequent processing into complex structures.	Mannose	78-85	prion protein	Homo sapiens	86-90
12713659-6	2003	In scrapie-infected neuroblastoma cells, however, high mannose PrPC glycoforms were preferred substrates for the formation of PrP-scrapie (PrPSc).	Mannose	55-62	prion protein	Homo sapiens	63-67
12713659-6	2003	In scrapie-infected neuroblastoma cells, however, high mannose PrPC glycoforms were preferred substrates for the formation of PrP-scrapie (PrPSc).	Mannose	55-62	prion protein	Homo sapiens	63-66
12558975-5	2003	Basigin was found to bind to high mannose-carrying cell recognition molecules, such as myelin-associated glycoprotein, L1, the beta2-subunit of Na+/K+-ATPase and an oligomannosidic neoglycolipid.	Mannose	34-41	basigin	Mus musculus	0-7
12628695-3	2003	We describe an ELISA-like assay, based on biotinylated mannose-conjugated bovine serum albumin (BSA), which specifically binds to the cell mannose receptor.	Mannose	55-62	albumin	Homo sapiens	81-94
12565922-0	2003	Chemoenzymatic synthesis of high-mannose type HIV-1 gp120 glycopeptides.	Mannose	33-40	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	52-57
12565922-2	2003	Thus, the high-mannose type glycopeptides [gp120 (336-342)] containing Man(9), Man(6) and Man(5) moieties, respectively, were synthesized in satisfactory yields via transglycosylation to the acetylglucosaminyl peptide, using the recombinant Arthrobacter Endo-beta-N-acetyl-glucosaminidase (Endo-A) as the key enzyme.	Mannose	15-22	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	43-48
12565922-2	2003	Thus, the high-mannose type glycopeptides [gp120 (336-342)] containing Man(9), Man(6) and Man(5) moieties, respectively, were synthesized in satisfactory yields via transglycosylation to the acetylglucosaminyl peptide, using the recombinant Arthrobacter Endo-beta-N-acetyl-glucosaminidase (Endo-A) as the key enzyme.	Mannose	15-22	endo-beta-N-acetylglucosaminidase	Homo sapiens	254-288
12565922-2	2003	Thus, the high-mannose type glycopeptides [gp120 (336-342)] containing Man(9), Man(6) and Man(5) moieties, respectively, were synthesized in satisfactory yields via transglycosylation to the acetylglucosaminyl peptide, using the recombinant Arthrobacter Endo-beta-N-acetyl-glucosaminidase (Endo-A) as the key enzyme.	Mannose	15-22	endo-beta-N-acetylglucosaminidase	Homo sapiens	290-296
12734794-0	2003	Glucose-mannose-binding lectins isolated from Brazilian beans stimulate the autophosphorylation of the insulin receptor in vitro.	Mannose	8-15	insulin receptor	Homo sapiens	103-119
12558975-5	2003	Basigin was found to bind to high mannose-carrying cell recognition molecules, such as myelin-associated glycoprotein, L1, the beta2-subunit of Na+/K+-ATPase and an oligomannosidic neoglycolipid.	Mannose	34-41	myelin-associated glycoprotein	Mus musculus	87-117
12519401-1	2003	The purpose was to evaluate the possible association of serum mannose binding lectin (s-MBL) levels on type of triggering microbe, duration of diarrhoea, incidence and course of reactive arthritis (ReA) caused by Salmonella, Yersinia and Campylobacter.	Mannose	62-69	mannose binding lectin 2	Homo sapiens	88-91
12506357-0	2003	Sperm surface hyaluronan binding protein (HABP1) interacts with zona pellucida of water buffalo (Bubalus bubalis) through its clustered mannose residues.	Mannose	136-143	complement C1q binding protein	Rattus norvegicus	42-47
12506357-4	2003	Recently, we have demonstrated the specificity of clustered mannose as another ligand for HABP1 (Kumar et al., 2001: J Biosci 26:325-332).	Mannose	60-67	complement C1q binding protein	Rattus norvegicus	90-95
12506357-7	2003	This data suggests the specific interaction of HABP1 with ZP, through clustered mannose residues.	Mannose	80-87	complement C1q binding protein	Rattus norvegicus	47-52
12506357-10	2003	This suggests that sperm surface HABP1 may act as mannose binding sites for zona recognition.	Mannose	50-57	complement C1q binding protein	Rattus norvegicus	33-38
12432463-0	2003	Mannose-specific lectin activity of parasporal proteins from a lepidoptera-specific Bacillus thuringiensis strain.	Mannose	0-7	hemocytin	Bombyx mori	17-23
12432463-5	2003	Lectin activity of our isolate was strongly inhibited by preincubation with D-mannose, but not with the six other monosaccharides: D-galactose, D-glucose, L-fucose, N-acetyl- D-glucosamine, N-acetyl- D-galactosamine, and N-acetylneuraminic acid.	Mannose	76-85	hemocytin	Bombyx mori	0-6
12670046-1	2003	Fungal roselipins, discovered as inhibitors of diacylglycerol acyltransferase (DGAT), consist of three parts; highly methylated C20 fatty acid, mannose and arabinitol.	Mannose	144-151	diacylglycerol O-acyltransferase 1	Homo sapiens	47-77
14610287-4	2003	Langerin is a type II lectin with mannose specificity expressed by LCs in epidermis and epithelia.	Mannose	34-41	CD207 molecule	Homo sapiens	0-8
12508063-6	2003	AtSTP1 transports glucose, galactose, xylose, and mannose, but not fructose.	Mannose	50-57	sugar transporter 1	Arabidopsis thaliana	0-6
12496440-6	2003	Arg-Gly-Asp-Ser peptide and neo-glycoproteins galactose-BSA and mannose-BSA inhibited the Der f-induced IL-6 and TNF-alpha productions and enhanced accessory function of AMs.	Mannose	64-71	interleukin 6	Homo sapiens	104-108
12496440-6	2003	Arg-Gly-Asp-Ser peptide and neo-glycoproteins galactose-BSA and mannose-BSA inhibited the Der f-induced IL-6 and TNF-alpha productions and enhanced accessory function of AMs.	Mannose	64-71	tumor necrosis factor	Homo sapiens	113-122
14605497-3	2003	However, macrophage-targetted enzyme replacement using intravenous mannose-terminated human glucocerebrosidase (imiglucerase, Cerezyme) is highly effective in ameliorating many of the manifestations of Gaucher"s disease and is a treatment in widespread use.	Mannose	67-74	glucosylceramidase beta	Homo sapiens	112-124
12670046-1	2003	Fungal roselipins, discovered as inhibitors of diacylglycerol acyltransferase (DGAT), consist of three parts; highly methylated C20 fatty acid, mannose and arabinitol.	Mannose	144-151	diacylglycerol O-acyltransferase 1	Homo sapiens	79-83
12488138-3	2002	We report here that a mixture of hypochlorous acid (HOCl) and nitrite (NO 2 - ) induces nitration, oxidation, and chlorination of tyrosine residues in human SP-A and inhibits SP-A"s ability to aggregate lipids and bind mannose.	Mannose	219-226	surfactant protein A1	Homo sapiens	175-179
12608536-1	2003	PURPOSE: To improve target specificity and uptake of liposomes by macrophages, one can improve high-affinity receptor binding to mannose determinants with their 175-kDa mannose receptor (MR), which is mainly influenced by the length and flexibility of the spacer between the carbohydrate head group and liposome surface.	Mannose	129-136	mannose receptor C-type 1	Homo sapiens	169-185
12935358-3	2003	Co-operative signaling by TLR1 and TLR2 is observed using either non-capped or mannose-capped LAM as a stimulus.	Mannose	79-86	toll like receptor 1	Homo sapiens	26-30
12935358-3	2003	Co-operative signaling by TLR1 and TLR2 is observed using either non-capped or mannose-capped LAM as a stimulus.	Mannose	79-86	toll like receptor 2	Homo sapiens	35-39
12399458-5	2002	Endo180 is shown to bind in a Ca(2+)-dependent manner to mannose, fucose, and N-acetylglucosamine but not to galactose.	Mannose	57-64	mannose receptor C type 2	Homo sapiens	0-7
12485445-0	2002	Mannose binding lectin (MBL) polymorphisms associated with low MBL production in patients with dermatomyositis.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
12499404-5	2002	Treatment of the alpha-GalA with the alpha-mannosidase resulted in the exposure of a Man-6-P residue on a nonreduced end of oligosaccharide chains after the removal of phosphodiester-linked nonreduced-end mannose.	Mannose	205-212	galactosidase alpha	Homo sapiens	17-27
12499404-5	2002	Treatment of the alpha-GalA with the alpha-mannosidase resulted in the exposure of a Man-6-P residue on a nonreduced end of oligosaccharide chains after the removal of phosphodiester-linked nonreduced-end mannose.	Mannose	205-212	alpha-mannosidase	Saccharomyces cerevisiae S288C	37-54
12485445-0	2002	Mannose binding lectin (MBL) polymorphisms associated with low MBL production in patients with dermatomyositis.	Mannose	0-7	mannose binding lectin 2	Homo sapiens	63-66
12485445-3	2002	Here we focused on mannose binding lectin (MBL), which is one of several proteins involved in clearance of apoptotic cells and could thereby lessen photosensitive autoimmunity.	Mannose	19-26	mannose binding lectin 2	Homo sapiens	43-46
12235155-7	2002	Both proteins contain a DXD motif found in the active site of many glycosyltransferases, and mutations in this motif in Mnn9p or Van1p reveal that both proteins contribute to mannose polymerization.	Mannose	175-182	mannosyltransferase complex subunit MNN9	Saccharomyces cerevisiae S288C	120-125
12473150-3	2002	The carbohydrate-binding ability of MBL can be inhibited by simple sugars like mannose, fucose and N-acetylglucosamine, but its greatest avidity appears to be for repeating mannose-based structural patterns typical of microbial surfaces.	Mannose	79-86	mannose binding lectin 2	Homo sapiens	36-39
12473150-3	2002	The carbohydrate-binding ability of MBL can be inhibited by simple sugars like mannose, fucose and N-acetylglucosamine, but its greatest avidity appears to be for repeating mannose-based structural patterns typical of microbial surfaces.	Mannose	173-180	mannose binding lectin 2	Homo sapiens	36-39
12235155-7	2002	Both proteins contain a DXD motif found in the active site of many glycosyltransferases, and mutations in this motif in Mnn9p or Van1p reveal that both proteins contribute to mannose polymerization.	Mannose	175-182	Van1p	Saccharomyces cerevisiae S288C	129-134
12409145-2	2002	In response to a high glucose concentration (27.5 mM), PAI-1 mRNA increased within 2 h, peaked at 4 h, remained elevated for another 4 h, then decreased to basal levels at 24 h. On the other hand, mannose at the same concentration (22.5 mM mannose plus 5.5 mM glucose) as an osmotic control had little effect on PAI-1 mRNA expression.	Mannose	197-204	serpin family E member 1	Rattus norvegicus	55-60
12414893-7	2002	IL-8 production by HCG was not affected by inhibitors of protein kinases A and C. In contrast, this stimulation was attenuated by D-mannose, which inhibits binding to C-type lectins.	Mannose	130-139	C-X-C motif chemokine ligand 8	Homo sapiens	0-4
12409145-2	2002	In response to a high glucose concentration (27.5 mM), PAI-1 mRNA increased within 2 h, peaked at 4 h, remained elevated for another 4 h, then decreased to basal levels at 24 h. On the other hand, mannose at the same concentration (22.5 mM mannose plus 5.5 mM glucose) as an osmotic control had little effect on PAI-1 mRNA expression.	Mannose	240-247	serpin family E member 1	Rattus norvegicus	55-60
12406749-8	2002	Carbohydrate competition experiments indicated that glucose, glucosamine, mannose, and fructose were taken up by the same system as NAG.	Mannose	74-81	N-acetyl-alpha-glucosaminidase	Homo sapiens	132-135
12478387-1	2002	The Saccharomyces cerevisiae Och1p is required for the initiation of the mannose outer chain elongation of cell wall mannoproteins.	Mannose	73-80	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	29-34
12384422-5	2002	The O-regions of the O8 and O9 LPSs consist of a mannose homopolysaccharide (MHP), while that of O111 consists of a heteropolysaccharide (not including mannose), and K-12 LPS lacks an O-region.	Mannose	49-56	toll-like receptor 4	Mus musculus	31-34
12784674-9	2002	In "02, it is clarified that a glycosylation enzyme, POMGnT1 which modifies GlcNAc onto ser/thr-mannose, is defective in 6 MEB patients.	Mannose	96-103	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)	Homo sapiens	53-60
12244146-7	2002	Monocyte-derived macrophages on an SP-A substrate demonstrated enhanced pinocytosis of mannose BSA and phagocytosis of Mycobacterium tuberculosis lipoarabinomannan-coated microspheres.	Mannose	87-94	surfactant protein A1	Homo sapiens	35-39
12202476-0	2002	Role of N-linked oligosaccharide flexibility in mannose phosphorylation of lysosomal enzyme cathepsin L.	Mannose	48-55	cathepsin L	Homo sapiens	92-103
12202476-6	2002	Mutagenesis of residues that surround Lys-54 and Lys-99 and demonstration of mannose phosphorylation of a glycosylated derivative of green fluorescent protein provide strong evidence that the cathepsin L phosphorylation signal is a simple structure composed of as few as two well placed lysine residues.	Mannose	77-84	cathepsin L	Homo sapiens	192-203
12228272-7	2002	Alveolar macrophages isolated from BCG-vaccinated guinea pigs produced significantly more IL-8 mRNA and protein when stimulated for 24 h with heat-killed H37Ra, heat-killed H37Rv, and H37Rv cell wall, but not mannose-capped lipoarabinomannan (ManLAM), than did cells stimulated with media alone.	Mannose	209-216	interleukin-8	Cavia porcellus	90-94
12244199-3	2002	Other collectins, such as mannose-binding lectin and the collectin-like C1q, have been shown to bind to apoptotic cells and drive ingestion through interaction with calreticulin and CD91 on the phagocyte in vitro.	Mannose	26-33	calreticulin	Mus musculus	165-177
12244146-8	2002	The newly expressed MR likely came from intracellular pools because: 1) up-regulation of the MR by SP-A occurred by 1 h, 2) new protein synthesis was not necessary for MR up-regulation, and 3) pinocytosis of mannose BSA via MR recycling was increased.	Mannose	208-215	mannose receptor C-type 1	Homo sapiens	20-22
12244146-8	2002	The newly expressed MR likely came from intracellular pools because: 1) up-regulation of the MR by SP-A occurred by 1 h, 2) new protein synthesis was not necessary for MR up-regulation, and 3) pinocytosis of mannose BSA via MR recycling was increased.	Mannose	208-215	mannose receptor C-type 1	Homo sapiens	93-95
12244199-3	2002	Other collectins, such as mannose-binding lectin and the collectin-like C1q, have been shown to bind to apoptotic cells and drive ingestion through interaction with calreticulin and CD91 on the phagocyte in vitro.	Mannose	26-33	low density lipoprotein receptor-related protein 1	Mus musculus	182-186
12244146-8	2002	The newly expressed MR likely came from intracellular pools because: 1) up-regulation of the MR by SP-A occurred by 1 h, 2) new protein synthesis was not necessary for MR up-regulation, and 3) pinocytosis of mannose BSA via MR recycling was increased.	Mannose	208-215	surfactant protein A1	Homo sapiens	99-103
12244146-8	2002	The newly expressed MR likely came from intracellular pools because: 1) up-regulation of the MR by SP-A occurred by 1 h, 2) new protein synthesis was not necessary for MR up-regulation, and 3) pinocytosis of mannose BSA via MR recycling was increased.	Mannose	208-215	mannose receptor C-type 1	Homo sapiens	93-95
12244146-8	2002	The newly expressed MR likely came from intracellular pools because: 1) up-regulation of the MR by SP-A occurred by 1 h, 2) new protein synthesis was not necessary for MR up-regulation, and 3) pinocytosis of mannose BSA via MR recycling was increased.	Mannose	208-215	mannose receptor C-type 1	Homo sapiens	93-95
12234361-6	2002	C-type lectins such as DC-SIGN contain a lectin domain that recognizes in a Ca2+-dependent manner carbohydrates such as mannose-containing structures presented on the glycoproteins ICAM-2 and ICAM-3.	Mannose	120-127	intercellular adhesion molecule 2	Homo sapiens	181-187
12473263-5	2002	Addition of glucose (100mM) or mannose (100mM), and to some extent galactose (100mM), but not fructose (100mM) to the co-cultures, partly inhibited the monocyte IL-6 co-culture response, but such addition did not inhibit the in vitro monocyte lipopolysaccharide (LPS)-generated IL-6 secretion.	Mannose	31-38	interleukin 6	Homo sapiens	161-165
12473263-6	2002	When mannose was added to the co-cultures, monocyte IL-6 mRNA expression was eradicated in malignant co-cultures and reduced to a low level in benign co-cultures.	Mannose	5-12	interleukin 6	Homo sapiens	52-56
12055199-6	2002	By contrast, IM persists as a mannose-rich polypeptide that interacts with the endoplasmic reticulum resident molecular chaperone calnexin.	Mannose	30-37	calnexin	Homo sapiens	130-138
12110688-6	2002	The binding interface is constituted of three stacked alpha1--&gt;2-linked mannose rings for Man-9 and two stacked mannose rings for hexamannoside with the rest of the saccharide molecules pointing to the solution.	Mannose	75-82	mannosidase alpha class 1A member 1	Homo sapiens	93-98
12234361-6	2002	C-type lectins such as DC-SIGN contain a lectin domain that recognizes in a Ca2+-dependent manner carbohydrates such as mannose-containing structures presented on the glycoproteins ICAM-2 and ICAM-3.	Mannose	120-127	intercellular adhesion molecule 3	Homo sapiens	192-198
12222658-5	2002	Significant TNF-stimulating activity was found in the extractable polysaccharide fraction, which was hydrolyzed and found to contain glucose, galactose, arabinose, rhamnose, and mannose.	Mannose	178-185	tumor necrosis factor	Rattus norvegicus	12-15
12161184-3	2002	Administration of mannose-terminated glucocerebrosidase (Cerezyme) resulted in the reduction of GL-1 levels in the livers of these animals.	Mannose	18-25	glucosidase, beta, acid	Mus musculus	37-55
11986323-1	2002	N-Acetylglucosaminyltransferase III (GlcNAc-TIII), the product of the Mgat3 gene, transfers the bisecting GlcNAc to the core mannose of complex N-glycans.	Mannose	125-132	mannoside acetylglucosaminyltransferase 3	Mus musculus	70-75
12072528-0	2002	The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.	Mannose	4-11	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	113-118
12072529-0	2002	The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1--&gt;2 mannose residues on the outer face of gp120.	Mannose	118-125	adrenoceptor alpha 1D	Homo sapiens	104-110
12072529-0	2002	The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1--&gt;2 mannose residues on the outer face of gp120.	Mannose	118-125	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	156-161
12072529-8	2002	Consistent with this finding, the binding of 2G12 to gp120 could be inhibited by monomeric mannose but not by galactose, glucose, or N-acetylglucosamine.	Mannose	91-98	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	53-58
12112240-4	2002	Disruption of the H. polymorpha PMI40 homologue (HpPMI40) resulted in the auxotrophic requirement for D-mannose.	Mannose	102-111	mannose-6-phosphate isomerase PMI40	Saccharomyces cerevisiae S288C	32-37
12112240-5	2002	The heterologous expressions of HpYPT1 and HpPMI40 were able to complement the temperature-sensitive phenotype of S. cerevisiae ypt1-1 mutant and the mannose auxotrophy of S. cerevisiae pmi40 null mutant, respectively, indicating that the H. polymorpha genes encode the functional homologues of S. cerevisiae YPT1 and PMI40 proteins.	Mannose	150-157	mannose-6-phosphate isomerase PMI40	Saccharomyces cerevisiae S288C	186-191
12112240-5	2002	The heterologous expressions of HpYPT1 and HpPMI40 were able to complement the temperature-sensitive phenotype of S. cerevisiae ypt1-1 mutant and the mannose auxotrophy of S. cerevisiae pmi40 null mutant, respectively, indicating that the H. polymorpha genes encode the functional homologues of S. cerevisiae YPT1 and PMI40 proteins.	Mannose	150-157	Rab family GTPase YPT1	Saccharomyces cerevisiae S288C	34-38
12112240-5	2002	The heterologous expressions of HpYPT1 and HpPMI40 were able to complement the temperature-sensitive phenotype of S. cerevisiae ypt1-1 mutant and the mannose auxotrophy of S. cerevisiae pmi40 null mutant, respectively, indicating that the H. polymorpha genes encode the functional homologues of S. cerevisiae YPT1 and PMI40 proteins.	Mannose	150-157	mannose-6-phosphate isomerase PMI40	Saccharomyces cerevisiae S288C	45-50
12036889-5	2002	Binding of Pg 1 to isolated TF was inhibited by 6-aminohexanoic acid and alpha-methylmannoside, suggesting that Pg 1 L-lysine binding sites and the biantennary, mannose-containing N-linked oligosaccharide chain are involved in this interaction.	Mannose	161-168	coagulation factor III, tissue factor	Homo sapiens	28-30
12033803-6	2002	Furthermore, a calibration model using a PLS1 was proposed for the quantification of mannose in the samples obtained by precipitation with 60% ethanol aqueous solutions.	Mannose	85-92	plastin 1	Homo sapiens	41-45
11916969-6	2002	Mannose, glucose, maltose, and inositol, at millimolar concentrations, competed for human SP-D binding to the bacterial membrane.	Mannose	0-7	surfactant protein D	Homo sapiens	90-94
11960993-6	2002	Competition binding studies using monosaccharides demonstrate that CG2958 interacts specifically with fucose and mannose.	Mannose	113-120	lectin-24Db	Drosophila melanogaster	67-73
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	Mannose	144-151	myelin basic protein	Homo sapiens	108-111
11850428-5	2002	The crystal structures of MBP-A soaked with monosaccharides and disaccharides and also the structure of the MBP-A trimer cross-linked by a high mannose asparaginyl oligosaccharide reveal that monosaccharides or alpha1-6-linked mannose bind to MBP-A in one orientation, whereas alpha1-2- or alpha1-3-linked mannose binds in an orientation rotated 180 degrees around a local symmetry axis relating the 3- and 4-OH groups.	Mannose	144-151	myelin basic protein	Homo sapiens	108-111
11934491-7	2002	Binding of Lf was not inhibited by transferrin (Tf) and Lf moiety molecules (mannose, galactose, and lactose) but by Lf.	Mannose	77-84	lactotransferrin	Bos taurus	11-13
11872745-1	2002	VIP36, an intracellular lectin that recognizes high mannose-type glycans (Hara-Kuge, S., Ohkura, T., Seko, A., and Yamashita, K. (1999) Glycobiology 9, 833-839), was shown to localize not only to the early secretory pathway but also to the plasma membrane of Madin-Darby canine kidney (MDCK) cells.	Mannose	52-59	lectin, mannose binding 2	Canis lupus familiaris	0-5
11872745-8	2002	Furthermore, the overproduction of VIP36 greatly stimulated the secretion of a major apical secretory glycoprotein of MDCK cells, clusterin, which was found to carry at least one high mannose-type glycan and to be recognized by VIP36.	Mannose	184-191	lectin, mannose binding 2	Canis lupus familiaris	35-40
11872745-10	2002	These results indicated that VIP36 was involved in the transport and sorting of glycoproteins carrying high mannose-type glycan(s).	Mannose	108-115	lectin, mannose binding 2	Canis lupus familiaris	29-34
11996831-3	2002	From D-lyxose, D-mannose and 6-deoxy-L-mannose (L-rhamnose) are obtained mixtures of ketoses and C-2 epimeric aldoses.	Mannose	15-24	complement C2	Homo sapiens	97-100
11999341-0	2002	Immunoregulatory activities of lactoferrin in the delayed type hypersensitivity in mice are mediated by a receptor with affinity to mannose.	Mannose	132-139	lactotransferrin	Mus musculus	31-42
11868814-8	2002	The lectins Con A and PSA recognized purified sperm surface PH-20 after Western blotting, suggesting that mannose is a major sugar within or at the terminal end of the linked glycan.	Mannose	106-113	sperm adhesion molecule 1	Homo sapiens	60-65
12849009-4	2002	Soluble proteins such as C1q, mannose-binding lectin, surfactant proteins A and D, C-reactive protein, C3bi, beta2-glycoprotein I and growth arrest specific gene-6 bind to apoptotic cells and act as "opsonins" thus favouring their clearance.	Mannose	30-37	C-reactive protein	Homo sapiens	83-101
11834744-7	2002	X-ray crystallographic structures of CLC protein in complex with the inhibitors showed that p-chloromercuribenzenesulfonate bound CLC protein via disulfide bonds with Cys(29) and with Cys(57) near the carbohydrate recognition domain (CRD), whereas N-ethylmaleimide bound to the galectin-10 CRD via ring stacking interactions with Trp(72), in a manner highly analogous to mannose binding to this CRD.	Mannose	371-378	Charcot-Leyden crystal galectin	Homo sapiens	37-40
11834744-7	2002	X-ray crystallographic structures of CLC protein in complex with the inhibitors showed that p-chloromercuribenzenesulfonate bound CLC protein via disulfide bonds with Cys(29) and with Cys(57) near the carbohydrate recognition domain (CRD), whereas N-ethylmaleimide bound to the galectin-10 CRD via ring stacking interactions with Trp(72), in a manner highly analogous to mannose binding to this CRD.	Mannose	371-378	Charcot-Leyden crystal galectin	Homo sapiens	130-133
12815230-1	2002	UDP-GlcNAc:alpha6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II (GnT II; EC 2.4.1.143) is a medial-Golgi resident enzyme that catalyses an essential step in the biosynthetic pathway leading from high mannose to complex N-linked oligosaccharides.	Mannose	209-216	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	74-80
12655775-2	2002	The most prominent cycling lectin is the mannose-binding type I membrane protein ERGIC-53 (ERGIC protein of 53 kDa), a marker for the ERGIC, which functions as a cargo receptor to facilitate export of an increasing number of glycoproteins with different characteristics from the ER.	Mannose	41-48	lectin, mannose binding 1	Homo sapiens	81-89
11906616-1	2002	BACKGROUND/AIMS: The mannose-binding lectin (MBL) gene was reported to play an important role in determining the clinical outcome of persistent hepatitis B virus (HBV) infection.	Mannose	21-28	mannose binding lectin 2	Homo sapiens	45-48
11707454-3	2002	Incubation of HepG2 human hepatoma cells in glucose-free medium resulted in an increased HO-1 mRNA content, reaching a maximum of approximately 25-fold over control cells after 12 h. The glucose-dependent induction of HO-1 mRNA was concentration-dependent (k(12) approximately 0.5 mm) and was attenuated by fructose, galactose, mannose, and 2-deoxyglucose, but not by the non-metabolizable glucose analog, 3-O-methylglucose.	Mannose	328-335	heme oxygenase 1	Homo sapiens	218-222
12545205-7	2002	The positive reaction of N-cadherin from the WM35 cell line with Galanthus nivalis agglutinin (GNA), Datura stramonium agglutinin (DSA) and Sambucus nigra agglutinin (SNA) indicated the presence of high-mannose type glycans and biantennary complex type oligosaccharides with alpha2-6 linked sialic acid.	Mannose	203-210	cadherin 2	Homo sapiens	25-35
12511980-10	2002	The results of our study indicate that a receptor with an affinity for mannose is essential for the mediation of adjuvant lactoferrin function in the generation of DTH.	Mannose	71-78	lactotransferrin	Bos taurus	122-133
11784324-1	2002	Hyaluronan-binding protein 1 (HABP1), a ubiquitous multifunctional protein, interacts with hyaluronan, globular head of complement component 1q (gC1q), and clustered mannose and has been shown to be involved in cell signalling.	Mannose	166-173	complement C1q binding protein	Homo sapiens	0-28
11784324-1	2002	Hyaluronan-binding protein 1 (HABP1), a ubiquitous multifunctional protein, interacts with hyaluronan, globular head of complement component 1q (gC1q), and clustered mannose and has been shown to be involved in cell signalling.	Mannose	166-173	complement C1q binding protein	Homo sapiens	30-35
11868369-4	2002	Surfactant proteins A and D (pulmonary collectins) function as host defense lectins and play important roles in innate immunity in the lung-Collectins including SP-A, SP-D and mannose-binding proteins can bind CD14.	Mannose	176-183	surfactant protein A1	Homo sapiens	0-27
11868369-4	2002	Surfactant proteins A and D (pulmonary collectins) function as host defense lectins and play important roles in innate immunity in the lung-Collectins including SP-A, SP-D and mannose-binding proteins can bind CD14.	Mannose	176-183	CD14 molecule	Homo sapiens	210-214
12153112-1	2002	A cell-associated mannose-resistant hemagglutinating factor (HAF) was extracted from enteroinvasive Escherichia coli (EIEC) serotype O124:H- by sonication.	Mannose	18-25	coagulation factor XII	Homo sapiens	61-64
11737072-1	2001	Variant alleles of the mannose binding lectin (MBL) gene are associated with increased susceptibility to infection and polymorphisms of tumour necrosis factor and lymphotoxin alpha genes (TNF, LTA) are associated with increased severity of infection.	Mannose	23-30	mannose binding lectin 2	Homo sapiens	47-50
11749971-3	2001	By making use of electrospray mass spectrometry, the molecular mass of ZmERabp1 was determined to be 20,243 Da comprising a sugar moiety of 1865 Da, corresponding to a high mannose-type glycan structure.	Mannose	173-180	auxin-binding protein 1	Zea mays	71-79
11726395-5	2001	The effect of SP-A could be inhibited by high concentrations of mannose, but was not affected by the removal or addition of lipopolysaccharide (LPS).	Mannose	64-71	surfactant protein A1	Homo sapiens	14-18
11737072-1	2001	Variant alleles of the mannose binding lectin (MBL) gene are associated with increased susceptibility to infection and polymorphisms of tumour necrosis factor and lymphotoxin alpha genes (TNF, LTA) are associated with increased severity of infection.	Mannose	23-30	lymphotoxin alpha	Homo sapiens	163-180
11737072-1	2001	Variant alleles of the mannose binding lectin (MBL) gene are associated with increased susceptibility to infection and polymorphisms of tumour necrosis factor and lymphotoxin alpha genes (TNF, LTA) are associated with increased severity of infection.	Mannose	23-30	tumor necrosis factor	Homo sapiens	188-191
11814014-3	2001	In lactoferrin-a, the glycans linked to Asn-233 and Asn-545 were of the high-mannose type, whereas those present at Asn-368 and Asn-476 were complex-type ones.	Mannose	77-84	lactotransferrin	Bos taurus	3-14
11713608-5	2001	The two cathepsin L-secreting phenotypes were distinct in that they displayed differences in cathepsin trafficking, expression of mannose 6-phosphate/insulin-like growth factor receptor and expression of proliferin, a mannose-phosphorylated angiogenic factor.	Mannose	130-137	cathepsin L	Mus musculus	8-19
11732993-6	2001	The lectins MSL-1, MSL-2 and MSL-3 contained 5.7, 5.4 and 4.5% neutral sugars, respectively, and the sugar composition of the lectins was glucose and mannose for MSL-1 and galactose for both MSL-2 and MSL-3.	Mannose	150-157	MSL complex subunit 1	Rattus norvegicus	162-167
11737599-8	2001	Exposure of various cell types to high glucose or mannose (25 mmol/L) led to increased expression of importins alpha3, alpha5/hSRP1, and alpha7 in different cultured cells, while up-regulation of other importin alpha isoforms was less consistent.	Mannose	50-57	karyopherin subunit alpha 1	Homo sapiens	126-131
11737599-8	2001	Exposure of various cell types to high glucose or mannose (25 mmol/L) led to increased expression of importins alpha3, alpha5/hSRP1, and alpha7 in different cultured cells, while up-regulation of other importin alpha isoforms was less consistent.	Mannose	50-57	karyopherin subunit alpha 3	Rattus norvegicus	101-109
11748728-1	2001	The HXT5 gene encodes a functional hexose transporter that has moderate affinity for glucose (K(m)=10 mM), moderate to low affinity for fructose (K(m)=40 mM) and low affinity for mannose (K(m)&gt;100 mM).	Mannose	179-186	hexose transporter HXT5	Saccharomyces cerevisiae S288C	4-8
11712863-3	2001	Mannose-binding lectin (MBL) is a key factor in innate mucosal defenses and has several key single nucleotide polymorphisms (SNPs).	Mannose	0-7	mannose binding lectin 2	Homo sapiens	24-27
11739758-3	2001	The present study describes first, ManR, a new sigma(54)-associated activator, and second, Ell(t)(Man), a new sigma(54)-dependent PTS permease of the mannose family, both involved in sensitivity to mesentericin Y105, since interruption of their corresponding genes led to resistance of L. monocytogenes EGDe.	Mannose	150-157	elongation factor for RNA polymerase II	Homo sapiens	91-94
11744633-1	2001	The C-type carbohydrate-recognition domains of E-selectin and rat serum mannose-binding protein have similar structures.	Mannose	72-79	selectin E	Homo sapiens	47-57
11744633-2	2001	Selectin/mannose-binding protein chimeras created by transfer of key sequences from E-selectin into mannose-binding protein have previously been shown to bind the selectin ligand sialyl-Lewis(X) through a Ca(2+)-dependent subsite, common to many C-type lectins, and an accessory site containing positively charged amino acid residues.	Mannose	9-16	selectin E	Homo sapiens	84-94
11744633-2	2001	Selectin/mannose-binding protein chimeras created by transfer of key sequences from E-selectin into mannose-binding protein have previously been shown to bind the selectin ligand sialyl-Lewis(X) through a Ca(2+)-dependent subsite, common to many C-type lectins, and an accessory site containing positively charged amino acid residues.	Mannose	100-107	selectin E	Homo sapiens	84-94
11536148-4	2001	However, a variable proportion (5% to 15%) of high-mannose (Man5 to Man9) oligosaccharides were present.	Mannose	51-58	mannosidase alpha class 1A member 1	Homo sapiens	68-72
11710528-0	2001	Differential and cell-type specific microheterogeneity of high mannose-type Asn-linked oligosaccharides of human transferrin receptor.	Mannose	63-70	transferrin receptor	Homo sapiens	113-133
11710528-1	2001	The structural analysis of high mannose-type Asn-linked (N-linked) oligosaccharides of the human transferrin receptor (hTR) from D-[2-3H]mannose metabolic-radiolabeled human cells--A431, K562, BeWo, and HL60--was investigated.	Mannose	32-39	transferrin receptor	Homo sapiens	97-117
11710528-1	2001	The structural analysis of high mannose-type Asn-linked (N-linked) oligosaccharides of the human transferrin receptor (hTR) from D-[2-3H]mannose metabolic-radiolabeled human cells--A431, K562, BeWo, and HL60--was investigated.	Mannose	32-39	telomerase RNA component	Homo sapiens	119-122
11710528-3	2001	The composition analysis of hTR glycopeptides revealed that Con A-I contains both mannose and fucose, whereas Con A-III has mannose exclusively.	Mannose	82-89	telomerase RNA component	Homo sapiens	28-31
11676606-6	2001	Detailed carbohydrate analysis revealed high-mannose structures on sCD154 purified from Pichia pastoris, whereas CD154 purified from Chinese hamster ovary E1A contained heterogeneous populations of complex carbohydrates.	Mannose	45-52	CD40 ligand	Homo sapiens	68-73
11690653-9	2001	In addition, the present study demonstrates that the recombinant hST3Gal I polypeptides transiently expressed in COS-7 cells are glycosylated with complex and high mannose type glycans on each of the five potential N-glycosylation sites.	Mannose	164-171	tumor-suppressor, HELA cell type	Homo sapiens	65-69
11687298-1	2001	Dietary mannose is used to treat glycosylation deficient patients with mutations in phosphomannose isomerase (PMI), but there is little information on mannose metabolism in model systems.	Mannose	8-15	mannose phosphate isomerase	Homo sapiens	84-108
11710528-6	2001	Our results demonstrate that the high mannose-type oligosaccharides of hTR ranged in size from Man5-R to Man9-R with cell-type specific patterns.	Mannose	38-45	telomerase RNA component	Homo sapiens	71-74
11710528-6	2001	Our results demonstrate that the high mannose-type oligosaccharides of hTR ranged in size from Man5-R to Man9-R with cell-type specific patterns.	Mannose	38-45	mannosidase alpha class 1A member 1	Homo sapiens	105-109
11687298-1	2001	Dietary mannose is used to treat glycosylation deficient patients with mutations in phosphomannose isomerase (PMI), but there is little information on mannose metabolism in model systems.	Mannose	8-15	mannose phosphate isomerase	Homo sapiens	110-113
11687298-1	2001	Dietary mannose is used to treat glycosylation deficient patients with mutations in phosphomannose isomerase (PMI), but there is little information on mannose metabolism in model systems.	Mannose	91-98	mannose phosphate isomerase	Homo sapiens	110-113
11687298-12	2001	Mannose supplements had little effect on the specific activity of phosphomannomutase (Man-6-P&lt;--&gt;Man-1-P) in different organs, but specific activity of PMI in brain, intestine, muscle, heart and lung gradually increased &lt;2-fold with increasing mannose intake.	Mannose	0-7	mannose phosphate isomerase	Homo sapiens	158-161
11721968-7	2001	To clarify the binding mechanism, we compared mannose conjugates and a monomer of mannose regarding their effects on endocytosis and enhancement of CD14 and CD86 expression.	Mannose	46-53	CD14 molecule	Homo sapiens	148-152
11693915-12	2001	The Pad1p overexpressing transformants also showed a 22-25% faster glucose consumption rate, a 40-45% faster mannose consumption rate, and a 24-29% faster ethanol production rate in the dilute acid hydrolysate of spruce.	Mannose	109-116	phenylacrylic acid decarboxylase PAD1	Saccharomyces cerevisiae S288C	4-9
11530187-1	2001	Serum amyloid P component (SAP) binds in vitro Ca(2+)-dependently to several ligands including oligosaccharides with terminal mannose and galactose.	Mannose	126-133	amyloid P component, serum	Homo sapiens	0-25
11530187-1	2001	Serum amyloid P component (SAP) binds in vitro Ca(2+)-dependently to several ligands including oligosaccharides with terminal mannose and galactose.	Mannose	126-133	amyloid P component, serum	Homo sapiens	27-30
11530187-6	2001	Binding studies indicated that galactose, mannose and fucose moieties contributed to the SAP reacting site(s).	Mannose	42-49	amyloid P component, serum	Homo sapiens	89-92
11574402-9	2001	The nonmetabolizable glucose analog 2-deoxyglucose, which has no mitogenic effect, induced HSL approximately 1.3-fold, whereas mannose was similar to glucose, stimulating HSL expression 1.7- to 2-fold.	Mannose	127-134	lipase E, hormone sensitive type	Rattus norvegicus	171-174
11590221-2	2001	We show that human macrophages synthesize PAF-AH as a premedial Golgi precursor containing high mannose N-linked glycans.	Mannose	96-103	phospholipase A2 group VII	Homo sapiens	42-48
11721968-7	2001	To clarify the binding mechanism, we compared mannose conjugates and a monomer of mannose regarding their effects on endocytosis and enhancement of CD14 and CD86 expression.	Mannose	46-53	CD86 molecule	Homo sapiens	157-161
11721968-7	2001	To clarify the binding mechanism, we compared mannose conjugates and a monomer of mannose regarding their effects on endocytosis and enhancement of CD14 and CD86 expression.	Mannose	82-89	CD14 molecule	Homo sapiens	148-152
11721968-7	2001	To clarify the binding mechanism, we compared mannose conjugates and a monomer of mannose regarding their effects on endocytosis and enhancement of CD14 and CD86 expression.	Mannose	82-89	CD86 molecule	Homo sapiens	157-161
11490002-6	2001	Transfection experiments of HeLa cells and biochemical analyses revealed that cathepsin W is exclusively "high mannose-type" glycosylated and is mainly targeted to the endoplasmic reticulum (ER).	Mannose	111-118	cathepsin W	Homo sapiens	78-89
11567096-1	2001	Rat corticotropin-releasing factor receptor 1 (rCRFR1) was produced either in transfected HEK 293 cells as a complex glycosylated protein or in the presence of the mannosidase I inhibitor kifunensine as a high mannose glycosylated protein.	Mannose	210-217	corticotropin releasing hormone	Rattus norvegicus	4-34
11567096-1	2001	Rat corticotropin-releasing factor receptor 1 (rCRFR1) was produced either in transfected HEK 293 cells as a complex glycosylated protein or in the presence of the mannosidase I inhibitor kifunensine as a high mannose glycosylated protein.	Mannose	210-217	corticotropin releasing hormone receptor 1	Rattus norvegicus	47-53
11560994-0	2001	C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells.	Mannose	8-15	calreticulin	Homo sapiens	58-70
11560994-0	2001	C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells.	Mannose	8-15	LDL receptor related protein 1	Homo sapiens	75-79
11560994-3	2001	Here we provide evidence that C1q and mannose binding lectin (MBL), a member of the collectin family of proteins, bind to apoptotic cells and stimulate ingestion of these by ligation on the phagocyte surface of the multifunctional protein, calreticulin (also known as the cC1qR), which in turn is bound to the endocytic receptor protein CD91, also known as the alpha-2-macroglobulin receptor.	Mannose	38-45	mannose binding lectin 2	Homo sapiens	62-65
11560994-3	2001	Here we provide evidence that C1q and mannose binding lectin (MBL), a member of the collectin family of proteins, bind to apoptotic cells and stimulate ingestion of these by ligation on the phagocyte surface of the multifunctional protein, calreticulin (also known as the cC1qR), which in turn is bound to the endocytic receptor protein CD91, also known as the alpha-2-macroglobulin receptor.	Mannose	38-45	calreticulin	Homo sapiens	240-252
11560994-3	2001	Here we provide evidence that C1q and mannose binding lectin (MBL), a member of the collectin family of proteins, bind to apoptotic cells and stimulate ingestion of these by ligation on the phagocyte surface of the multifunctional protein, calreticulin (also known as the cC1qR), which in turn is bound to the endocytic receptor protein CD91, also known as the alpha-2-macroglobulin receptor.	Mannose	38-45	calreticulin	Homo sapiens	272-277
11560994-3	2001	Here we provide evidence that C1q and mannose binding lectin (MBL), a member of the collectin family of proteins, bind to apoptotic cells and stimulate ingestion of these by ligation on the phagocyte surface of the multifunctional protein, calreticulin (also known as the cC1qR), which in turn is bound to the endocytic receptor protein CD91, also known as the alpha-2-macroglobulin receptor.	Mannose	38-45	LDL receptor related protein 1	Homo sapiens	337-341
11560994-3	2001	Here we provide evidence that C1q and mannose binding lectin (MBL), a member of the collectin family of proteins, bind to apoptotic cells and stimulate ingestion of these by ligation on the phagocyte surface of the multifunctional protein, calreticulin (also known as the cC1qR), which in turn is bound to the endocytic receptor protein CD91, also known as the alpha-2-macroglobulin receptor.	Mannose	38-45	LDL receptor related protein 1	Homo sapiens	361-391
11545593-0	2001	Trichoderma reesei alpha-1,2-mannosidase: structural basis for the cleavage of four consecutive mannose residues.	Mannose	96-103	mannosidase alpha class 1A member 2	Homo sapiens	19-40
11545593-3	2001	mannosidases cleave only one mannose to produce the Man8B isomer, an alpha-1,2-mannosidase from Trichoderma reesei can sequentially cleave all four 1,2-linked mannose sugars from a Man(9)GlcNAc(2) oligosaccharide, a feature reminiscent of the activity of Golgi mannosidases.	Mannose	29-36	mannosidase alpha class 1A member 2	Homo sapiens	69-90
11518779-13	2001	In conclusion, a significant modulation of several human MC functions exerted by serum IgA with increased exposure of GalNAc, Neu5Acalpha2,6GalNAc, and mannose residues isolated from IgAN patients is reported for the first time.	Mannose	152-159	IGAN1	Homo sapiens	183-187
11568477-0	2001	Evidence for clustered mannose as a new ligand for hyaluronan- binding protein (HABP1) from human fibroblasts.	Mannose	23-30	complement C1q binding protein	Homo sapiens	80-85
11509633-5	2001	This interaction involves the carbohydrate recognition domain of MBL, because it was calcium dependent and inhibited by mannose and by mAb against this domain of MBL.	Mannose	120-127	mannose binding lectin 2	Homo sapiens	65-68
11390392-2	2001	IL-2 initially binds a high mannose-type glycan and a specific peptide sequence of the IL-2 receptor alpha-subunit and sequentially forms a high affinity complex of IL-2.IL-2 receptor alpha-, beta-, and gamma-subunits.	Mannose	28-35	interleukin 2	Homo sapiens	0-4
11485330-1	2001	Altering the carbohydrate binding properties of surfactant protein D (SP-D) [e.g., by replacing its carbohydrate recognition domain (CRD) with that of either mannose binding lectin (MBL) or conglutinin] can increase its activity against influenza A virus (IAV).	Mannose	158-165	surfactant protein D	Homo sapiens	70-74
11472912-6	2001	The S. cerevisiae mnn2 mutant, with a mannan content similar to that of gms1Delta, also showed high coflocculation (35%) and was sensitive to mannose inhibition.	Mannose	142-149	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	18-22
11384997-6	2001	Both DC-SIGN and DC-SIGNR bind ligands bearing mannose and related sugars through the CRDs.	Mannose	47-54	C-type lectin domain family 4 member M	Homo sapiens	17-25
11469797-6	2001	The results showed that beta 1,4-GalT widely affects N-glycan processing by competing with GnT-IV, GnT-V, and alpha-mannosidase II in cells and also by some other mechanisms that suppress the conversion of high-mannose-type sugar chains to the hybrid type.	Mannose	211-218	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	Mus musculus	24-37
11472912-7	2001	Coflocculation of P. damnosus and gms1Delta (or mnn2) also could be inhibited by gms1Delta mannan (with unbranched alpha-1,6-linked mannose residues), concanavalin A (mannose and glucose specific), or NPA lectin (specific for alpha-1,6-linked mannosyl units).	Mannose	132-139	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	48-52
11530213-4	2001	We show that GTP gamma S inhibits the synthesis of dolichol-phosphate-mannose, which is the donor of the mannose residues for GPI biosynthesis.	Mannose	70-77	glucose-6-phosphate isomerase	Homo sapiens	126-129
11530213-6	2001	All the data obtained suggest the involvement of classical heterotrimeric G proteins in the regulation of GPI-anchor biosynthesis through dolichol-phosphate-mannose synthesis via the activation of adenylyl cyclase and protein phosphorylation.	Mannose	157-164	glucose-6-phosphate isomerase	Homo sapiens	106-109
11401985-3	2001	We found a cluster of six genes, termed sfpA, sfpH, sfpC, sfpD, sfpJ, and sfpG, which mediate mannose-resistant hemagglutination and the expression of fimbriae.	Mannose	94-101	w0006	Escherichia coli	40-44
11356840-0	2001	The essential Smp3 protein is required for addition of the side-branching fourth mannose during assembly of yeast glycosylphosphatidylinositols.	Mannose	81-88	glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase	Saccharomyces cerevisiae S288C	14-18
11356840-3	2001	We report that temperature-sensitive smp3 mutants accumulate a GPI containing three mannoses and that smp3 is epistatic to the gpi11, gpi13, and gaa1 mutations, which normally result in the accumulation of Man(4)-GPIs, including the presumed substrate for the yeast GPI transamidase.	Mannose	84-92	phosphatidylinositol glycan anchor biosynthesis class Z	Homo sapiens	37-41
11356840-3	2001	We report that temperature-sensitive smp3 mutants accumulate a GPI containing three mannoses and that smp3 is epistatic to the gpi11, gpi13, and gaa1 mutations, which normally result in the accumulation of Man(4)-GPIs, including the presumed substrate for the yeast GPI transamidase.	Mannose	84-92	glucose-6-phosphate isomerase	Homo sapiens	63-66
11356840-3	2001	We report that temperature-sensitive smp3 mutants accumulate a GPI containing three mannoses and that smp3 is epistatic to the gpi11, gpi13, and gaa1 mutations, which normally result in the accumulation of Man(4)-GPIs, including the presumed substrate for the yeast GPI transamidase.	Mannose	84-92	glycosylphosphatidylinositol anchor attachment 1	Homo sapiens	145-149
11356840-7	2001	Smp3-related proteins are encoded in the genomes of Schizosaccharomyces pombe, Candida albicans, Drosophila melanogaster, and Homo sapiens and form a subgroup of a family of proteins, the other groups of which are defined by the Pig-B(Gpi10) protein, which adds the third GPI mannose, and by the Alg9 and Alg12 proteins, which act in the dolichol pathway for N-glycosylation.	Mannose	276-283	phosphatidylinositol glycan anchor biosynthesis class Z	Homo sapiens	0-4
11568522-7	2001	Partial enteral nutrition alone increased mucosal weight, villus width and cross-sectional area, LPH activity, mRNA expression, and high mannose LPH precursor (proLPHh) abundance compared with TPN (P&lt;0.05).	Mannose	137-144	lactase	Homo sapiens	145-148
11337510-2	2001	Serum mannose-binding protein (MBP) initiates the lectin branch of the complement cascade by binding to sugars on the surfaces of microorganisms and activating two MBP-associated serine proteases (MASP-1 and MASP-2).	Mannose	6-13	myelin basic protein	Homo sapiens	31-34
11337510-2	2001	Serum mannose-binding protein (MBP) initiates the lectin branch of the complement cascade by binding to sugars on the surfaces of microorganisms and activating two MBP-associated serine proteases (MASP-1 and MASP-2).	Mannose	6-13	myelin basic protein	Homo sapiens	164-167
11337510-2	2001	Serum mannose-binding protein (MBP) initiates the lectin branch of the complement cascade by binding to sugars on the surfaces of microorganisms and activating two MBP-associated serine proteases (MASP-1 and MASP-2).	Mannose	6-13	MBL associated serine protease 1	Homo sapiens	197-203
11337510-2	2001	Serum mannose-binding protein (MBP) initiates the lectin branch of the complement cascade by binding to sugars on the surfaces of microorganisms and activating two MBP-associated serine proteases (MASP-1 and MASP-2).	Mannose	6-13	MBL associated serine protease 2	Homo sapiens	208-214
23105314-1	2001	A C-type mannose specific lectin (LRP) isolated from plasma of fresh water fishLabeo rohita showed 500 times higher specificity towards cell surface oligosaccharide (LAM) ofMycobacterium tuberculosis (H37Rv).	Mannose	9-16	LDL receptor related protein 1	Homo sapiens	34-37
11278778-11	2001	In addition to these Alg11-related proteins, Alg11p is also similar to Alg2p, a protein that regulates the addition of the third mannose to the core oligosaccharide.	Mannose	129-136	ALG11 alpha-1,2-mannosyltransferase	Homo sapiens	45-51
11444772-3	2001	Enterococcus faecalis has been shown previously to produce an endo-beta-N-acetylglucosaminidase activity which cleaves high mannose-type glycans in glycoproteins between the N-acetylglucosamine residues of the pentasaccharide core.	Mannose	124-131	O-GlcNAcase	Homo sapiens	67-95
11448753-3	2001	Root NR was activated by anoxia or by addition of uncoupler (CCCP) or mannose.	Mannose	70-77	nitrate reductase [NADH]-like	Cucumis sativus	5-7
11448753-12	2001	Our data indicate that, as in barley roots, anoxia, uncouplers, and mannose feeding activate cucumber root NR, at least partly, by enhancing NR dephosphorylation via a decrease in the internal level of ATP and a concomitant cellular acidification.	Mannose	68-75	nitrate reductase [NADH]-like	Cucumis sativus	107-109
11448753-12	2001	Our data indicate that, as in barley roots, anoxia, uncouplers, and mannose feeding activate cucumber root NR, at least partly, by enhancing NR dephosphorylation via a decrease in the internal level of ATP and a concomitant cellular acidification.	Mannose	68-75	nitrate reductase [NADH]-like	Cucumis sativus	141-143
11278778-11	2001	In addition to these Alg11-related proteins, Alg11p is also similar to Alg2p, a protein that regulates the addition of the third mannose to the core oligosaccharide.	Mannose	129-136	ALG2 alpha-1,3/1,6-mannosyltransferase	Homo sapiens	71-76
11432403-1	2001	PROBLEM: Asymmetric IgG antibodies (AAb) possess a mannose-rich oligosaccharide residue bound to one of the Fab regions, making them unable to activate immunoeffector mechanisms.	Mannose	51-58	FA complementation group B	Homo sapiens	108-111
11390503-7	2001	Mannose binding lectin and lung surfactant protein A, other ligands of C1qR(P), also enhanced ingestion of suboptimally opsonized IgG-fAbeta, whereas control proteins did not.	Mannose	0-7	CD93 antigen	Mus musculus	71-78
11406099-7	2001	It is concluded that both rat intestinal and renal apical membrane have a concentrative, saturable, electrogenic and Na(+)-dependent D-mannose transport mechanism, which is different from SGLT1.	Mannose	135-142	solute carrier family 5 member 1	Rattus norvegicus	188-193
11292596-6	2001	The dissociation constant of Man-BSA and MBP decreased dramatically with increasing density of mannose, but the Michaelis-Menten constant of hepatic uptake of Man-BSA was not so sensitive to the change in density.	Mannose	95-102	myelin basic protein	Homo sapiens	41-44
11254551-2	2001	The objective of this investigation was to examine the role of mitogen-activated protein (MAP) kinase (MAPK) and nuclear factor kappaB (NF-kappaB) signaling pathways in the regulation of iNOS and NO* by a mycobacterial cell wall lipoglycan known as mannose-capped lipoarabinomannan (ManLAM).	Mannose	249-256	nitric oxide synthase 2, inducible	Mus musculus	187-191
11311123-1	2001	The key glycolytic HXK2 gene, coding for the enzyme hexokinase 2 (Hxk2p), is expressed when cells of the yeast Saccharomyces cerevisiae are grown on a fermentable medium using glucose, fructose or mannose as a carbon source.	Mannose	197-204	hexokinase 2	Saccharomyces cerevisiae S288C	19-23
11311123-1	2001	The key glycolytic HXK2 gene, coding for the enzyme hexokinase 2 (Hxk2p), is expressed when cells of the yeast Saccharomyces cerevisiae are grown on a fermentable medium using glucose, fructose or mannose as a carbon source.	Mannose	197-204	hexokinase 2	Saccharomyces cerevisiae S288C	52-64
11311123-1	2001	The key glycolytic HXK2 gene, coding for the enzyme hexokinase 2 (Hxk2p), is expressed when cells of the yeast Saccharomyces cerevisiae are grown on a fermentable medium using glucose, fructose or mannose as a carbon source.	Mannose	197-204	hexokinase 2	Saccharomyces cerevisiae S288C	66-71
11361219-2	2001	OBJECTIVE: To determine whether variant alleles of the mannose binding lectin (MBL) gene causing low serum concentrations of MBL are associated with increased susceptibility to rheumatoid arthritis (RA) and erosive outcome in an inception cohort of patients with early polyarthritis.	Mannose	55-62	mannose binding lectin 2	Homo sapiens	79-82
11361219-2	2001	OBJECTIVE: To determine whether variant alleles of the mannose binding lectin (MBL) gene causing low serum concentrations of MBL are associated with increased susceptibility to rheumatoid arthritis (RA) and erosive outcome in an inception cohort of patients with early polyarthritis.	Mannose	55-62	mannose binding lectin 2	Homo sapiens	125-128
11359567-9	2001	The fact that the man1 mutant was not pathogenic suggests that blocking mannose synthesis could be fungicidal in the mammalian host and thus an excellent target for antifungal drug development.	Mannose	72-79	LEM domain containing 3	Homo sapiens	18-22
11278527-7	2001	These results suggest that removal of the terminal mannose from the central branch acts as a timer in dictating the degradation of transport-incompetent, glycosylated Ig subunits in a calnexin-independent way.	Mannose	51-58	calnexin	Homo sapiens	184-192
11414366-4	2001	Mannose-binding lectin (MBL) is also a collagenous lectin in serum that is specific for GlcNAc and mannose binding.	Mannose	99-106	mannose binding lectin 2	Homo sapiens	0-22
11414366-4	2001	Mannose-binding lectin (MBL) is also a collagenous lectin in serum that is specific for GlcNAc and mannose binding.	Mannose	99-106	mannose binding lectin 2	Homo sapiens	24-27
11436565-0	2001	[Modification of a method for detecting the post-phoretic activity of mannose (Mpi, EC 5.3.1.8)- and glucose (Gpi, EC5.3.1.9)-6-phosphate isomerase].	Mannose	70-77	mannose phosphate isomerase	Homo sapiens	79-82
11350186-6	2001	Short-term low-dose oral mannose supplementation improved her transferrin IEF pattern and normalized her antithrombin III activity, further substantiating the beneficial effect of mannose in CDG-Ib.	Mannose	25-32	serpin family C member 1	Homo sapiens	105-121
11312005-1	2001	Leishmania donovani GP36 glycoprotein is the main antigen of the FML Fucose Mannose Ligand (FML) complex specifically recognized by sera of kala-azar human patients.	Mannose	76-83	podoplanin	Homo sapiens	20-24
11254728-8	2001	Purified human S100A8/A9 complex and recombinant human annexin I showed carboxylate-dependent binding to immobilized bovine lung carboxylated glycans and recognized a subset of mannose-labeled endothelial glycoproteins immunoprecipitated by mAbGB3.1.	Mannose	177-184	S100 calcium binding protein A8	Homo sapiens	15-21
11308323-4	2001	The purified glycosylated bovine beta-casein was specific only to Concanavalin A, and the oligosaccharide structure of glycosylated beta-casein was of high-mannose type.	Mannose	156-163	casein beta	Bos taurus	33-44
11308323-4	2001	The purified glycosylated bovine beta-casein was specific only to Concanavalin A, and the oligosaccharide structure of glycosylated beta-casein was of high-mannose type.	Mannose	156-163	casein beta	Bos taurus	132-143
11084042-1	2001	Phosphomannose isomerase (PMI) catalyzes the reversible interconversion of fructose 6-phosphate and mannose 6-phosphate, which is the first step in the biosynthesis of activated mannose donors required for the biosynthesis of various glycoconjugates.	Mannose	7-14	mannose phosphate isomerase	Mus musculus	26-29
11374071-5	2001	The level of the high-mannose form of AQP2-A147T in the plasma membranes was low, indicating that this mutation has a less severe effect on proper folding.	Mannose	22-29	aquaporin 2	Homo sapiens	38-42
11295122-1	2001	OBJECTIVE: To investigate the relationship between mannose-binding protein(MBP) gene codon 54 (GGC/GAC) polymorphism and the patterns of glomerular immune deposition in IgA nephropathy (IgAN) and explore its functional significance.	Mannose	51-58	myelin basic protein	Homo sapiens	75-78
11295122-1	2001	OBJECTIVE: To investigate the relationship between mannose-binding protein(MBP) gene codon 54 (GGC/GAC) polymorphism and the patterns of glomerular immune deposition in IgA nephropathy (IgAN) and explore its functional significance.	Mannose	51-58	gamma-glutamylcyclotransferase	Homo sapiens	95-98
11327242-2	2001	OBJECTIVE: To determine whether low mannose binding lectin (MBL) is associated with poor prognosis in rheumatoid arthritis (RA) and whether patients with RA have increased frequency of MBL deficiency.	Mannose	36-43	mannose binding lectin 2	Homo sapiens	60-63
11076950-1	2001	Interleukin-2 (IL-2) specifically recognizes high-mannose type glycans with five or six mannosyl residues.	Mannose	50-57	interleukin 2	Mus musculus	0-13
11076950-1	2001	Interleukin-2 (IL-2) specifically recognizes high-mannose type glycans with five or six mannosyl residues.	Mannose	50-57	interleukin 2	Mus musculus	15-19
11223423-0	2001	Synthesis of active high mannose-type lipoprotein lipase in human adipose tissues.	Mannose	25-32	lipoprotein lipase	Homo sapiens	38-56
11248658-8	2001	In addition, pro cat K demonstrated susceptibility to treatment with N-glycosidase F, suggesting the presence of high-mannose-containing oligosaccharides.	Mannose	118-125	cathepsin K	Homo sapiens	17-22
11357226-2	2001	In the present study the effects of biomedically relevant hexose sugars (glucose, fructose, galactose, mannose) and sucrose disaccharide on the expression of COX-1 and COX-2 genes were evaluated in granulation tissue fibroblasts, hypertrophic scar fibroblasts and keloid fibroblasts.	Mannose	103-110	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	158-163
11357226-2	2001	In the present study the effects of biomedically relevant hexose sugars (glucose, fructose, galactose, mannose) and sucrose disaccharide on the expression of COX-1 and COX-2 genes were evaluated in granulation tissue fibroblasts, hypertrophic scar fibroblasts and keloid fibroblasts.	Mannose	103-110	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	168-173
11357226-7	2001	On the other hand, COX-2 mRNA expression in granulation tissue fibroblasts was decreased dramatically in the presence of fructose, mannose and sucrose and moderately in the presence of galactose.	Mannose	131-138	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	19-24
11231270-9	2001	The carbohydrate of chanterelle basidiolipids consists solely of mannose, i.e. Cc1, Man alpha-3 or -6Man alpha; Cc2, Man alpha-3(Man alpha-6)Man alpha-.	Mannose	65-72	C-C motif chemokine ligand 14	Homo sapiens	79-82
11260138-6	2001	TLR4-negative renal epithelial cells, A498, are non-responsive to purified LPS, however, they respond to viable bacteria via a mannose-sensitive attachment-mediated pathway.	Mannose	127-134	toll like receptor 4	Homo sapiens	0-4
11260159-10	2001	Polyamine oxidase shows only one N-glycosilation site whose carbohydrate moiety seems to be composed of a branched chain of seven ordered sugars, i.e. two N-acetyl-D-glucosamine-, three mannose-, one fucose- and one xylose-residues.	Mannose	186-193	polyamine oxidase	Homo sapiens	0-17
11162499-5	2001	The sis1 mutant also displays glucose and mannose resistant phenotypes and has an osmo-tolerant phenotype during early seedling development.	Mannose	42-49	Protein kinase superfamily protein	Arabidopsis thaliana	4-8
11179331-13	2001	Unlike CD14 binding, EDTA and excess mannose attenuated the binding of MBP-A to rough LPS.	Mannose	37-44	mannose binding lectin 1	Rattus norvegicus	71-76
11525517-5	2001	The effects of Pi status on Ugp expression were confirmed using leaves of both pho1-2 and pho2-1 mutants of Arabidopsis (Pi-deficient and Pi-accumulating, respectively) and by feeding the leaves with D-mannose, which acts as a sink for Pi.	Mannose	200-209	UDP-GLUCOSE PYROPHOSPHORYLASE 1	Arabidopsis thaliana	28-31
11173531-5	2001	In COS-1 cells transfected with the cDNAs, DPPX-S and DPPX-L were initially synthesized as 113-kDa and 117-kDa forms, respectively, with high-mannose type oligosaccharides, which were then converted to 115-kDa and 120-kDa forms, mostly with the complex-type sugar chains.	Mannose	142-149	dipeptidyl peptidase like 6	Rattus norvegicus	43-47
11173531-5	2001	In COS-1 cells transfected with the cDNAs, DPPX-S and DPPX-L were initially synthesized as 113-kDa and 117-kDa forms, respectively, with high-mannose type oligosaccharides, which were then converted to 115-kDa and 120-kDa forms, mostly with the complex-type sugar chains.	Mannose	142-149	dipeptidyl peptidase like 6	Rattus norvegicus	54-58
11169219-3	2001	Both in vivo and in vitro the maximum production of CSFs occurred 6 h after initiation of stimulation, and returned to the background levels by 48 h. Mannose 6-P, mannose 1-P and mannose, and not other sugars inhibited the SAP-induced production of CSFs by macrophages which suggests that SAP interaction with macrophages was mediated by specific glycoprotein-receptors.	Mannose	163-170	amyloid P component, serum	Mus musculus	223-226
11169219-3	2001	Both in vivo and in vitro the maximum production of CSFs occurred 6 h after initiation of stimulation, and returned to the background levels by 48 h. Mannose 6-P, mannose 1-P and mannose, and not other sugars inhibited the SAP-induced production of CSFs by macrophages which suggests that SAP interaction with macrophages was mediated by specific glycoprotein-receptors.	Mannose	163-170	amyloid P component, serum	Mus musculus	289-292
11226175-0	2001	PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER.	Mannose	26-33	GPI mannosyltransferase 1	Sus scrofa	0-5
11226175-3	2001	In particular, mammalian and protozoan mannosyltransferases needed for addition of the first mannose (GPI-MT-I) have different substrate specificities and are targets of species- specific inhibitors of GPI biosynthesis.	Mannose	93-100	phosphatidylinositol glycan anchor biosynthesis class M	Homo sapiens	102-110
11226175-8	2001	PIG-M has a functionally important DXD motif, a characteristic of many glycosyltransferases, within a domain facing the lumen of the endoplasmic reticulum (ER), indicating that transfer of the first mannose to GPI occurs on the lumenal side of the ER membrane.	Mannose	199-206	GPI mannosyltransferase 1	Sus scrofa	0-5
11367522-1	2001	Mannose-binding lectin (MBL), a serum lectin specific for mannose or N-acetylglucosamine (GlcNAc), which contains both a collagen-like domain and a carbohydrate-recognition domain (CRD), plays a role in innate immunity by acting as an opsonin and activating complement in association with MBL-associated serine protease (MASP) via the lectin pathway.	Mannose	58-65	mannose binding lectin 2	Homo sapiens	0-22
11367522-1	2001	Mannose-binding lectin (MBL), a serum lectin specific for mannose or N-acetylglucosamine (GlcNAc), which contains both a collagen-like domain and a carbohydrate-recognition domain (CRD), plays a role in innate immunity by acting as an opsonin and activating complement in association with MBL-associated serine protease (MASP) via the lectin pathway.	Mannose	58-65	mannose binding lectin 2	Homo sapiens	24-27
11327611-4	2001	No sera recognized the 100-kd high mannose precursor form of the TSHR.	Mannose	35-42	thyroid stimulating hormone receptor	Homo sapiens	65-69
11160338-7	2001	However, other proteins that are structurally homologous to SP-A, mannose-binding lectin and complement protein 1q, did not.	Mannose	66-73	surfactant protein A1	Homo sapiens	60-64
11342172-1	2001	We show that cell surface glycans, sialic acid and mannose-containing species, are involved beside glycosaminoglycans (GAGs), heparan sulfate and chondroitin sulfate in the binding of full length (1--68) RANTES not only to CCR5 positive human primary lymphocytes or macrophages but also to CCR5 negative monocytic U937 cells.	Mannose	51-58	C-C motif chemokine receptor 5	Homo sapiens	223-227
11342172-1	2001	We show that cell surface glycans, sialic acid and mannose-containing species, are involved beside glycosaminoglycans (GAGs), heparan sulfate and chondroitin sulfate in the binding of full length (1--68) RANTES not only to CCR5 positive human primary lymphocytes or macrophages but also to CCR5 negative monocytic U937 cells.	Mannose	51-58	C-C motif chemokine receptor 5	Homo sapiens	290-294
11179430-1	2001	The Lec35 gene product (Lec35p) is required for utilization of the mannose donor mannose-P-dolichol (MPD) in synthesis of both lipid-linked oligosaccharides (LLOs) and glycosylphosphatidylinositols, which are important for functions such as protein folding and membrane anchoring, respectively.	Mannose	67-74	mannose-P-dolichol utilization defect 1	Homo sapiens	4-9
11179430-1	2001	The Lec35 gene product (Lec35p) is required for utilization of the mannose donor mannose-P-dolichol (MPD) in synthesis of both lipid-linked oligosaccharides (LLOs) and glycosylphosphatidylinositols, which are important for functions such as protein folding and membrane anchoring, respectively.	Mannose	67-74	mannose-P-dolichol utilization defect 1	Homo sapiens	24-30
11179430-1	2001	The Lec35 gene product (Lec35p) is required for utilization of the mannose donor mannose-P-dolichol (MPD) in synthesis of both lipid-linked oligosaccharides (LLOs) and glycosylphosphatidylinositols, which are important for functions such as protein folding and membrane anchoring, respectively.	Mannose	67-74	mevalonate diphosphate decarboxylase	Homo sapiens	81-99
11179430-1	2001	The Lec35 gene product (Lec35p) is required for utilization of the mannose donor mannose-P-dolichol (MPD) in synthesis of both lipid-linked oligosaccharides (LLOs) and glycosylphosphatidylinositols, which are important for functions such as protein folding and membrane anchoring, respectively.	Mannose	67-74	mevalonate diphosphate decarboxylase	Homo sapiens	101-104
11179430-8	2001	By testing the water-soluble MPD analog mannose-beta-1-P-citronellol in an in vitro system in which the MPD utilization defect was preserved by permeabilization with streptolysin-O, it was determined that Lec35p is not directly required for the enzymatic transfer of mannose from the donor to the acceptor substrate.	Mannose	40-47	mevalonate diphosphate decarboxylase	Homo sapiens	29-32
16233148-2	2001	N-Acetylglucosaminyltransferase I (GnT-I), which catalyzes the transfer of an N-acetylglucosamine residue from UDP-N-acetylglucosamine to the alpha1,3-linked mannose on Man5GlcNAc2 (M5), is a critical enzyme for the synthesis of high-mannose-type to complex-type glycan structures in N-linked glycan processing.	Mannose	158-165	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	35-40
11714623-5	2001	Other cell surface receptors including mannose binding protein on macrophages and DC-SIGN on dendritic cells also interact with gp120 on virus particles but do not actively promote fusion and virus entry.	Mannose	39-46	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	128-133
16233148-5	2001	The relative activity of MBP-fused GnT-I toward high-mannose-type N-linked oligosaccharides was 100% for Man5GlcNAc2, 52% for Man3GlcNAc2, 17% for Man6GlcNAc2.	Mannose	53-60	myelin basic protein	Homo sapiens	25-28
16233148-5	2001	The relative activity of MBP-fused GnT-I toward high-mannose-type N-linked oligosaccharides was 100% for Man5GlcNAc2, 52% for Man3GlcNAc2, 17% for Man6GlcNAc2.	Mannose	53-60	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	35-40
16233148-9	2001	Immobilization of MBP-fused GnT-I on the amylose resin led to an 80% yield of the high mannose-type-of oligosaccharide.	Mannose	87-94	myelin basic protein	Homo sapiens	18-21
16233148-9	2001	Immobilization of MBP-fused GnT-I on the amylose resin led to an 80% yield of the high mannose-type-of oligosaccharide.	Mannose	87-94	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	28-33
11190675-0	2001	MR60/ERGIC-53, a mannose-specific shuttling intracellular membrane lectin.	Mannose	17-24	lectin, mannose binding 1	Homo sapiens	0-4
11190675-0	2001	MR60/ERGIC-53, a mannose-specific shuttling intracellular membrane lectin.	Mannose	17-24	lectin, mannose binding 1	Homo sapiens	5-13
11135118-5	2000	Transport of D-galactose and D-mannose is also up to 60% less in Atstp1 seedlings compared to wild type, but transport of D-fructose, L-arabinose and sucrose is not reduced.	Mannose	29-38	sugar transporter 1	Arabidopsis thaliana	65-71
11125826-3	2000	Whilst D-mannose showed a beta-relaxation similar in strength to D-glucose, its deoxy sugar, L-rhamnose showed a relatively weak beta-relaxation.	Mannose	7-16	amyloid beta precursor protein	Homo sapiens	24-30
11102520-2	2000	An alternate glucosidase II-independent deglucosylation pathway exists, in which endo-alpha-mannosidase cleaves internally the glucose-substituted mannose residue of oligosaccharides.	Mannose	147-154	mannosidase endo-alpha	Homo sapiens	81-103
11159927-2	2000	Analysis of the attached carbohydrates shows those present on IgG1-Lec 1 were mannose terminated.	Mannose	78-85	LOC105243590	Mus musculus	62-66
11135118-6	2000	Germination of Atstp1 seed shows reduced sensitivity to D-mannose, demonstrating that AtSTP1 is active before germination.	Mannose	56-65	sugar transporter 1	Arabidopsis thaliana	15-21
11135118-6	2000	Germination of Atstp1 seed shows reduced sensitivity to D-mannose, demonstrating that AtSTP1 is active before germination.	Mannose	56-65	sugar transporter 1	Arabidopsis thaliana	86-92
10915796-7	2000	This residue is the mannose cleaved from Man(9)GlcNAc(2) by the endoplasmic reticulum alpha1, 2-mannosidase I to form Man(8)GlcNAc(2) isomer B.	Mannose	20-27	mannosidase alpha class 1A member 2	Homo sapiens	86-107
11089535-5	2000	Carbohydrate residues of the G2320R Tg mutant were of the high-mannose ER type, as shown by sensitivity to the treatment with endoglycosidase H. Molecular chaperones, GRP94, GRP78, and calreticulin, were all accumulated in the rdw rat thyroid glands.	Mannose	63-70	thyroglobulin	Rattus norvegicus	36-38
10931938-4	2000	Strains with a nonfunctional IPT1 allele lacked mannose-(inositol-phosphate)(2)-ceramide in their plasma membranes, bound significantly less DmAMP1 compared with wild-type strains, and were highly resistant to DmAMP1-mediated membrane permeabilization.	Mannose	48-57	inositolphosphotransferase	Saccharomyces cerevisiae S288C	29-33
10921916-7	2000	The interaction between CD45 and GII is dependent on the active site of GII, is mediated through the carbohydrate on CD45, and can be inhibited with mannose.	Mannose	149-156	protein tyrosine phosphatase receptor type C	Homo sapiens	24-28
10913141-1	2000	Mannose-binding protein (MBP; mannose-binding lectin) forms part of the innate immune system.	Mannose	30-37	myelin basic protein	Rattus norvegicus	0-23
10913141-1	2000	Mannose-binding protein (MBP; mannose-binding lectin) forms part of the innate immune system.	Mannose	30-37	myelin basic protein	Rattus norvegicus	25-28
11069660-9	2000	Gpr1 displayed a very low affinity for glucose (apparent Ka = 75 mM) and responded specifically to extracellular alpha and beta D-glucose and sucrose, but not to fructose, mannose or any glucose analogues tested.	Mannose	172-179	Gpr1p	Saccharomyces cerevisiae S288C	0-4
10946292-1	2000	Mannose (or mannan)-binding lectin (MBL) is an oligomeric serum lectin that plays a role in innate immunity by activating the complement system.	Mannose	0-7	mannose-binding lectin family member 3, pseudogene	Homo sapiens	36-39
10954751-5	2000	TbGPI10 also rescued the inviability of GPI10-disrupted S. cerevisiae, indicating that TbGPI10 is the orthologue of PIG-B/GPI10 that is involved in the transfer of the third mannose to GPI.	Mannose	174-181	putative glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase	Saccharomyces cerevisiae S288C	2-7
10954751-5	2000	TbGPI10 also rescued the inviability of GPI10-disrupted S. cerevisiae, indicating that TbGPI10 is the orthologue of PIG-B/GPI10 that is involved in the transfer of the third mannose to GPI.	Mannose	174-181	phosphatidylinositol glycan anchor biosynthesis class B	Sus scrofa	116-121
10954751-5	2000	TbGPI10 also rescued the inviability of GPI10-disrupted S. cerevisiae, indicating that TbGPI10 is the orthologue of PIG-B/GPI10 that is involved in the transfer of the third mannose to GPI.	Mannose	174-181	putative glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase	Saccharomyces cerevisiae S288C	40-45
10972885-4	2000	In addition to being insensitive to glucose and sucrose, the sis4/aba2 and sis5/abi4 mutants also display decreased sensitivity to the inhibitory effects of mannose on early seedling development.	Mannose	157-164	NAD(P)-binding Rossmann-fold superfamily protein	Arabidopsis thaliana	61-65
10972885-4	2000	In addition to being insensitive to glucose and sucrose, the sis4/aba2 and sis5/abi4 mutants also display decreased sensitivity to the inhibitory effects of mannose on early seedling development.	Mannose	157-164	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	75-79
10972885-4	2000	In addition to being insensitive to glucose and sucrose, the sis4/aba2 and sis5/abi4 mutants also display decreased sensitivity to the inhibitory effects of mannose on early seedling development.	Mannose	157-164	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	80-84
10972885-5	2000	Mutations in the ABI5 gene, but not mutations in the ABI1, ABI2 or ABI3 genes, also lead to weak glucose- and mannose-insensitive phenotypes.	Mannose	110-117	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	17-21
10929130-5	2000	MNN2 is an alpha-1, 2-mannosyltransferase catalyzing the addition of the first mannose to the branches on the poly l,6-mannose backbone of the outer chain of cell wall N-linked mannans.	Mannose	79-86	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	0-4
10913359-0	2000	Accessibility of the high-mannose glycans of glycoprotein gp120 from human immunodeficiency virus type 1 probed by in vitro interaction with mannose-binding lectins.	Mannose	26-33	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	58-63
10900005-6	2000	Activation of peripheral blood T cells results in the mannose 6 phosphorylation of CD26.	Mannose	54-61	dipeptidyl peptidase 4	Homo sapiens	83-87
10913359-0	2000	Accessibility of the high-mannose glycans of glycoprotein gp120 from human immunodeficiency virus type 1 probed by in vitro interaction with mannose-binding lectins.	Mannose	141-148	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	58-63
10913359-1	2000	The direct interaction of mannose-specific plant lectins with gp120 of HIV-1 was studied by surface plasmon resonance.	Mannose	26-33	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	62-67
10913359-5	2000	These results demonstrate that mannose-specific plant lectins are powerful tools to study the accessibility and elucidate the function of the gp120 glycans in the recognition and infection of the host cells by HIV-1.	Mannose	31-38	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	142-147
10913312-9	2000	These results suggest a role for an additional, mannose-specific, ER lectin in targeting secretory proteins to the proteasome for destruction.	Mannose	48-55	endoplasmic reticulum lectin 1	Homo sapiens	66-75
10913825-4	2000	We examined the enzyme activity of a glutathione S-transferase fusion of each VIG9 gene to synthesize GDP mannose in the cell extracts of a heterologous Escherichia coli expression system.	Mannose	106-113	mannose-1-phosphate guanylyltransferase	Saccharomyces cerevisiae S288C	78-82
10959866-2	2000	The method involves the 1--&gt;2-migration of the thioglucopyranosyl portion of the nonreducing disaccharide with inversion of configuration at C-2 of the mannopyranose ring and concomitant formation of the methyl glucopyranoside.	Mannose	155-168	complement C2	Homo sapiens	144-147
10801802-7	2000	Mannose and EDTA inhibited SP-D binding to CD14 but did not decrease SP-A binding.	Mannose	0-7	surfactant protein D	Rattus norvegicus	27-31
10801802-7	2000	Mannose and EDTA inhibited SP-D binding to CD14 but did not decrease SP-A binding.	Mannose	0-7	CD14 molecule	Rattus norvegicus	43-47
10891274-8	2000	In addition, the structure provides direct confirmation for the conversion of the ligand-binding site of the mannose-binding protein to an asialoglycoprotein receptor-like specificity suggested by Drickamer and colleagues.	Mannose	109-116	asialoglycoprotein receptor 1	Homo sapiens	139-166
10900005-9	2000	These results indicate that internalization of CD26 after cross-linking is mediated in part by M6P/IGFIIR and that the interaction between mannose 6-phosphorylated CD26 and M6P/IGFIIR may play an important role in CD26-mediated T cell costimulatory signaling.	Mannose	139-146	dipeptidyl peptidase 4	Homo sapiens	47-51
10900005-9	2000	These results indicate that internalization of CD26 after cross-linking is mediated in part by M6P/IGFIIR and that the interaction between mannose 6-phosphorylated CD26 and M6P/IGFIIR may play an important role in CD26-mediated T cell costimulatory signaling.	Mannose	139-146	dipeptidyl peptidase 4	Homo sapiens	164-168
10900005-9	2000	These results indicate that internalization of CD26 after cross-linking is mediated in part by M6P/IGFIIR and that the interaction between mannose 6-phosphorylated CD26 and M6P/IGFIIR may play an important role in CD26-mediated T cell costimulatory signaling.	Mannose	139-146	dipeptidyl peptidase 4	Homo sapiens	164-168
10929130-9	2000	MNN1 is an alpha-1,3-mannosyltransferase that adds the terminal mannose to the outer chain branches of N-linked mannan, masking mannosylphosphate.	Mannose	64-71	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	0-4
10801790-6	2000	When degradation or mannose trimming was inhibited, heavy chain formed a prolonged interaction with immunoglobulin heavy chain binding protein, ERp57, and protein disulfide isomerase.	Mannose	20-27	protein disulfide isomerase family A member 3	Homo sapiens	144-149
10878382-6	2000	In addition, two other CXCR-2 variants of 38 and 40 kDa were found to occur exclusively intracellular and to carry N-glycosylations of high mannose or hybrid type.	Mannose	140-147	C-X-C motif chemokine receptor 2	Homo sapiens	23-29
10781593-0	2000	Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositol.	Mannose	81-88	phosphatidylinositol glycan anchor biosynthesis class F	Sus scrofa	15-20
10781593-0	2000	Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositol.	Mannose	81-88	PIGO	Sus scrofa	25-30
10781593-9	2000	Therefore, mammalian cells have redundant activities in transferring phosphoethanolamine to the third mannose, both of which require PIG-F.	Mannose	102-109	phosphatidylinositol glycan anchor biosynthesis class F	Sus scrofa	133-138
10781593-5	2000	Pig-o knockout F9 embryonal carcinoma cells expressed very little GPI-anchored proteins and accumulated the same major GPI intermediate as the mouse class F mutant cell, which is defective in transferring phosphoethanolamine to the third mannose due to mutant Pig-f gene.	Mannose	238-245	PIGO	Sus scrofa	0-5
10781593-8	2000	A minor GPI intermediate seen in Pig-o knockout but not class F cells had more than three mannoses with phosphoethanolamines on the first and third mannoses, suggesting that this GPI may account for the low expression of GPI-anchored proteins.	Mannose	90-98	PIGO	Sus scrofa	33-38
10781593-8	2000	A minor GPI intermediate seen in Pig-o knockout but not class F cells had more than three mannoses with phosphoethanolamines on the first and third mannoses, suggesting that this GPI may account for the low expression of GPI-anchored proteins.	Mannose	148-156	PIGO	Sus scrofa	33-38
10919356-2	2000	Metabolic labeling experiments with [32]phosphate revealed that only the proform of cathepsin H acquired Man 6-P residues on its high mannose type oligosaccharide, and that most of the phosphorylated procathepsin H was secreted into the medium without having undergone significant intracellular dephosphorylation.	Mannose	134-141	cathepsin H	Homo sapiens	84-95
10793139-0	2000	Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose.	Mannose	181-188	mannose-ethanolamine phosphotransferase GPI11	Saccharomyces cerevisiae S288C	53-59
10748175-3	2000	As the sole provider of lumenal mannose, the Vrg4 protein functions as a key regulator of glycosylation in the yeast Golgi.	Mannose	32-39	GDP-mannose transporter	Saccharomyces cerevisiae S288C	45-49
10833030-4	2000	Ovalbumin was found to be glycosylated mainly with high-mannose and hybrid structures, consistent with profiles obtained on the intact glycoprotein by electrospray.	Mannose	56-63	ovalbumin (SERPINB14)	Gallus gallus	0-9
10788349-2	2000	Peroxidase-labeled concanavalin A (ConA) and wheat germ agglutinin (WGA) were used, as they specifically bind to saccharide residues most frequently encountered in biofilms matrices: D-glucose or D-mannose for ConA and N-acetyl-D-glucosamine or N-acetylneuraminic acid for WGA.	Mannose	196-205	peroxidase-like	Triticum aestivum	0-10
10880465-3	2000	Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a pheromone-response-pathway-dependent reporter (FUS1) in cells lacking a basal signal (ste4).	Mannose	110-117	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	36-40
10880465-3	2000	Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a pheromone-response-pathway-dependent reporter (FUS1) in cells lacking a basal signal (ste4).	Mannose	110-117	mannose-6-phosphate isomerase PMI40	Saccharomyces cerevisiae S288C	42-47
10880465-3	2000	Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a pheromone-response-pathway-dependent reporter (FUS1) in cells lacking a basal signal (ste4).	Mannose	110-117	mannose-1-phosphate guanylyltransferase	Saccharomyces cerevisiae S288C	49-53
10880465-3	2000	Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a pheromone-response-pathway-dependent reporter (FUS1) in cells lacking a basal signal (ste4).	Mannose	110-117	dolichyl-phosphate beta-D-mannosyltransferase	Saccharomyces cerevisiae S288C	55-59
10880465-3	2000	Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a pheromone-response-pathway-dependent reporter (FUS1) in cells lacking a basal signal (ste4).	Mannose	110-117	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	61-65
10880465-3	2000	Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a pheromone-response-pathway-dependent reporter (FUS1) in cells lacking a basal signal (ste4).	Mannose	110-117	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	67-72
10880465-3	2000	Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a pheromone-response-pathway-dependent reporter (FUS1) in cells lacking a basal signal (ste4).	Mannose	110-117	phosphatidylinositol N-acetylglucosaminyltransferase SPT14	Saccharomyces cerevisiae S288C	74-79
10880465-3	2000	Partial loss-of-function alleles of PGI1, PMI40, PSA1, DPM1, ALG1, MNN10, SPT14, and OCH1, genes required for mannose utilization and protein glycosylation, activated a pheromone-response-pathway-dependent reporter (FUS1) in cells lacking a basal signal (ste4).	Mannose	110-117	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	85-89
10880465-4	2000	Pathway activation was suppressed by the addition of mannose to hexose isomerase mutants pgi1-101 and pmi40-101, which bypassed the requirement for mannose biosynthesis in these mutants.	Mannose	53-60	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	89-93
10880465-4	2000	Pathway activation was suppressed by the addition of mannose to hexose isomerase mutants pgi1-101 and pmi40-101, which bypassed the requirement for mannose biosynthesis in these mutants.	Mannose	53-60	mannose-6-phosphate isomerase PMI40	Saccharomyces cerevisiae S288C	102-107
10880465-4	2000	Pathway activation was suppressed by the addition of mannose to hexose isomerase mutants pgi1-101 and pmi40-101, which bypassed the requirement for mannose biosynthesis in these mutants.	Mannose	148-155	glucose-6-phosphate isomerase	Saccharomyces cerevisiae S288C	89-93
10880465-4	2000	Pathway activation was suppressed by the addition of mannose to hexose isomerase mutants pgi1-101 and pmi40-101, which bypassed the requirement for mannose biosynthesis in these mutants.	Mannose	148-155	mannose-6-phosphate isomerase PMI40	Saccharomyces cerevisiae S288C	102-107
10880465-6	2000	Activation of FUS1 transcription in the mannose utilization/protein glycosylation mutants required some but not all proteins from three different signaling pathways: the pheromone response, invasive growth, and HOG pathways.	Mannose	40-47	Fus1p	Saccharomyces cerevisiae S288C	14-18
10880465-8	2000	Because loss of pheromone response pathway components leads to a synthetic growth defect in mannose utilization/protein glycosylation mutants, we suggest that the Sho1 --&gt; Ste12 pathway contributes to maintenance of cell wall integrity in vegetative cells.	Mannose	92-99	osmosensor SHO1	Saccharomyces cerevisiae S288C	163-167
10880465-8	2000	Because loss of pheromone response pathway components leads to a synthetic growth defect in mannose utilization/protein glycosylation mutants, we suggest that the Sho1 --&gt; Ste12 pathway contributes to maintenance of cell wall integrity in vegetative cells.	Mannose	92-99	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	175-180
10898509-2	2000	We now show that the selective advantage of the oxidized mannan-MUC1 is due to the presence of aldehydes and not Schiff bases, and that oxidized mannan-MUC1 binds to the mannose and not scavenger receptors and is internalized and presented by MHC class I molecules 1,000 times more efficiently than when reduced.	Mannose	170-177	mucin 1, cell surface associated	Homo sapiens	152-156
10793139-0	2000	Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose.	Mannose	181-188	mannose-ethanolamine phosphotransferase GPI13	Saccharomyces cerevisiae S288C	65-71
10793139-0	2000	Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose.	Mannose	181-188	mannose-ethanolamine phosphotransferase GPI13	Saccharomyces cerevisiae S288C	129-135
10691991-8	2000	Both glycans are xylose containing biantennary complex types that share the common core structural unit, Man1--&gt;6(Man1--&gt;3) (Xyl1--&gt;2)Man1--&gt;4GlcNAc1--&gt;4(Fuc1--&gt;3)GlcNAc for the major form, with an additional N-acetylglucosamine residue being linked, in the minor form, to one of the terminal mannose units of the core structure.	Mannose	311-318	LEM domain containing 3	Homo sapiens	105-109
10749748-9	2000	This effect was reversed when SP-A was incubated with either polyclonal rabbit anti-rat SP-A antibody or D-mannose.	Mannose	105-114	surfactant protein A1	Rattus norvegicus	30-34
10791783-5	2000	The glycan linked to Asn-281 of bovine lactoferrin-a was found to consist of fucose, galactose, and N-acetylgalactosamine in addition to mannose and N-acetylglucosamine.	Mannose	137-144	lactotransferrin	Bos taurus	39-50
10865191-4	2000	Mannose-capped LAM (MAN-LAM) acted in a different way in that TNF-alpha, GM-CSF, and IL-10 were upregulated after restimulation of MAC.	Mannose	0-7	tumor necrosis factor	Homo sapiens	62-71
10865191-4	2000	Mannose-capped LAM (MAN-LAM) acted in a different way in that TNF-alpha, GM-CSF, and IL-10 were upregulated after restimulation of MAC.	Mannose	0-7	colony stimulating factor 2	Homo sapiens	73-79
10865191-4	2000	Mannose-capped LAM (MAN-LAM) acted in a different way in that TNF-alpha, GM-CSF, and IL-10 were upregulated after restimulation of MAC.	Mannose	0-7	interleukin 10	Homo sapiens	85-90
10683235-4	2000	Concanavalin A was selected as the lectin due to the high mannose content of the oligosaccharide chain on AE1.	Mannose	58-65	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	106-109
10691991-8	2000	Both glycans are xylose containing biantennary complex types that share the common core structural unit, Man1--&gt;6(Man1--&gt;3) (Xyl1--&gt;2)Man1--&gt;4GlcNAc1--&gt;4(Fuc1--&gt;3)GlcNAc for the major form, with an additional N-acetylglucosamine residue being linked, in the minor form, to one of the terminal mannose units of the core structure.	Mannose	311-318	LEM domain containing 3	Homo sapiens	117-121
10691991-8	2000	Both glycans are xylose containing biantennary complex types that share the common core structural unit, Man1--&gt;6(Man1--&gt;3) (Xyl1--&gt;2)Man1--&gt;4GlcNAc1--&gt;4(Fuc1--&gt;3)GlcNAc for the major form, with an additional N-acetylglucosamine residue being linked, in the minor form, to one of the terminal mannose units of the core structure.	Mannose	311-318	LEM domain containing 3	Homo sapiens	117-121
10731714-4	2000	Protease digestion of bovine pancreatic RNase A and bovine a-lactalbumin was depressed in solutions (1 mM or so) of free N-glycans of both the high-mannose and complex types.	Mannose	148-155	ribonuclease pancreatic	Bos taurus	40-47
10671537-8	2000	With mannose removal, the glucose-untrimmed mutant forms of alpha(2)PI, which failed to bind to calnexin, were degraded by proteasomes.	Mannose	5-12	serpin family F member 2	Homo sapiens	60-70
10715554-12	2000	Both glycosylated truncated hFSH-R variants were sensitive to peptide-N-glycanase F and endoglycosidase H but insensitive to neuraminidase indicating that these variants possess high mannose type oligosaccharides.	Mannose	183-190	follicle stimulating hormone receptor	Homo sapiens	28-34
10679232-5	2000	Mannose, but not the nonmetabolized hexoses, 3-O-methylglucose or 2-deoxyglucose, increases glucokinase protein content.	Mannose	0-7	glucokinase	Homo sapiens	92-103
10671537-0	2000	Mannose trimming targets mutant alpha(2)-plasmin inhibitor for degradation by the proteasome.	Mannose	0-7	serpin family F member 2	Homo sapiens	32-58
10671537-10	2000	Our findings show that modification of oligosaccharides of the mutant forms of alpha(2)PI determines their recognition by the degradation apparatus and that mannose trimming is important for targeting the mutant alpha(2)PI proteins for the degradation pathway.	Mannose	157-164	serpin family F member 2	Homo sapiens	212-222
10652252-1	2000	The ER-Golgi intermediate compartment (ERGIC) marker ERGIC-53 is a mannose-specific membrane lectin operating as a cargo receptor for the transport of glycoproteins from the ER to the ERGIC.	Mannose	67-74	lectin, mannose binding 1	Homo sapiens	53-61
11310976-5	2000	In addition, glycophorin A from erythrocytes of a patient with CDA II but not CDA I exhibited a significant deficit of mannose and N-acetylglucosamine suggesting that its N-glycosylation site was also partly unglycosylated.	Mannose	119-126	glycophorin A (MNS blood group)	Homo sapiens	13-26
10783607-2	2000	Underlying the carbohydrate-deficient glycoprotein syndrome (CDGS) type 1b is a defect in phosphomannose isomerase (PMI), an enzyme of mannose metabolism.	Mannose	97-104	mannose phosphate isomerase	Homo sapiens	116-119
11310976-5	2000	In addition, glycophorin A from erythrocytes of a patient with CDA II but not CDA I exhibited a significant deficit of mannose and N-acetylglucosamine suggesting that its N-glycosylation site was also partly unglycosylated.	Mannose	119-126	SEC23 homolog B, COPII coat complex component	Homo sapiens	63-69
10580131-8	1999	Removal of mannose residues continues in the Golgi with the action of alpha1, 2-mannosidases IA and IB that can form Man(5)GlcNAc(2) and of alpha-mannosidase II that removes the alpha1,3- and alpha1,6-linked mannose from GlcNAcMan(5)GlcNAc(2) to form GlcNAcMan(3)GlcNAc(2).	Mannose	11-18	mannosidase alpha class 1A member 1	Homo sapiens	70-102
10661407-1	2000	We have identified a type II Ca2+-dependent lectin displaying mannose-binding specificity, exclusively expressed by Langerhans cells (LC), and named Langerin.	Mannose	62-69	CD207 molecule	Homo sapiens	149-157
11212708-0	2000	[Mannose-binding lectin(MBL) deficiency].	Mannose	1-8	mannose-binding lectin family member 3, pseudogene	Homo sapiens	24-27
10585852-7	1999	However, in contrast to TRP-1, tyrosinase presents a homogeneous high-mannose glycoform, also.	Mannose	70-77	tyrosinase	Mus musculus	31-41
10647178-5	1999	The crystal structures of Heltuba in complex with Man alpha 1-3Man and Man alpha 1-2Man, solved at 2.35 A and 2.45 A resolution respectively, reveal the carbohydrate-binding site and the residues required for the specificity towards alpha 1-3 or alpha 1-2 mannose linkages.	Mannose	256-263	adrenoceptor alpha 1D	Homo sapiens	54-61
10647178-5	1999	The crystal structures of Heltuba in complex with Man alpha 1-3Man and Man alpha 1-2Man, solved at 2.35 A and 2.45 A resolution respectively, reveal the carbohydrate-binding site and the residues required for the specificity towards alpha 1-3 or alpha 1-2 mannose linkages.	Mannose	256-263	adrenoceptor alpha 1D	Homo sapiens	75-82
10580135-5	1999	In addition to the well-understood role of mannose 6-phosphate receptor in lysosomal protein sorting, the vesicular integral protein of 36 kDa (VIP36) functions as a sorting receptor by recognizing high-mannose type glycans containing alpha1--&gt;2Man residues for transport from Golgi to the cell surface in polarized epithelial cells.	Mannose	43-50	lectin, mannose binding 2	Homo sapiens	106-142
10580135-5	1999	In addition to the well-understood role of mannose 6-phosphate receptor in lysosomal protein sorting, the vesicular integral protein of 36 kDa (VIP36) functions as a sorting receptor by recognizing high-mannose type glycans containing alpha1--&gt;2Man residues for transport from Golgi to the cell surface in polarized epithelial cells.	Mannose	43-50	lectin, mannose binding 2	Homo sapiens	144-149
10551804-0	1999	Mannose-dependent endoplasmic reticulum (ER)-Golgi intermediate compartment-53-mediated ER to Golgi trafficking of coagulation factors V and VIII.	Mannose	0-7	cytochrome c oxidase subunit 8A	Homo sapiens	141-145
10701081-8	1999	Concanavalin A lectin was used to isolate two groups of apolipoprotein H molecules bearing biantennary and truncated hybrids and high mannose and hybrid oligosaccharides.	Mannose	134-141	apolipoprotein H	Homo sapiens	56-72
11810515-3	1999	It has been found that the gp120 oligosaccharides are essential in HIV infection and that high-mannose type oligosaccharides present in the gp120 molecule are especially critical.	Mannose	95-102	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	140-145
10563827-0	1999	Selective Recognition of Mannose by the Human Eosinophil Charcot-Leyden Crystal Protein (Galectin-10): A Crystallographic Study at 1.8 A Resolution.	Mannose	25-32	Charcot-Leyden crystal galectin	Homo sapiens	57-87
10563827-0	1999	Selective Recognition of Mannose by the Human Eosinophil Charcot-Leyden Crystal Protein (Galectin-10): A Crystallographic Study at 1.8 A Resolution.	Mannose	25-32	Charcot-Leyden crystal galectin	Homo sapiens	89-100
10574991-0	1999	Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol.	Mannose	106-113	phosphatidylinositol glycan anchor biosynthesis class N	Homo sapiens	0-5
10574991-0	1999	Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol.	Mannose	106-113	mannose-ethanolamine phosphotransferase MCD4	Saccharomyces cerevisiae S288C	38-43
10574991-5	1999	In the Pig-n knockout cells, the first mannose in the GPI precursors was not modified by phosphoethanolamine.	Mannose	39-46	phosphatidylinositol glycan anchor biosynthesis class N	Sus scrofa	7-12
10561578-2	1999	Cathepsin E (CE), a nonlysosomal, intracellular aspartic proteinase, exists in several molecular forms that are N-glycosylated with high-mannose and/or complex-type oligosaccharides.	Mannose	137-144	cathepsin E	Rattus norvegicus	0-11
10561578-2	1999	Cathepsin E (CE), a nonlysosomal, intracellular aspartic proteinase, exists in several molecular forms that are N-glycosylated with high-mannose and/or complex-type oligosaccharides.	Mannose	137-144	cathepsin E	Rattus norvegicus	13-15
10578050-1	1999	Serum mannan binding protein (MBP), a mannose/N-acetylglusosamine-specific lectin, is important in innate immunity.	Mannose	38-45	myelin basic protein	Homo sapiens	6-28
10578050-1	1999	Serum mannan binding protein (MBP), a mannose/N-acetylglusosamine-specific lectin, is important in innate immunity.	Mannose	38-45	myelin basic protein	Homo sapiens	30-33
10551804-2	1999	ERGIC-53 is a homo-hexameric transmembrane lectin localized to the ERGIC that exhibits mannose-selective properties in vitro.	Mannose	87-94	lectin, mannose binding 1	Homo sapiens	0-8
10537138-4	1999	On the other hand, the effects of other inhibitors, swainsonine and deoxymannojirimycin, were much lower, suggesting that the high mannose-type carbohydrate side-chain is essential to the expression of a fully functional hSR.	Mannose	131-138	HSR	Homo sapiens	221-224
10510295-12	1999	The combinatorial effect of the entire region leads to the regulated transcription of GLK1, i.e., silent in media with glucose and other preferred carbon sources, such as fructose or mannose, and increased levels of expression upon glucose depletion.	Mannose	183-190	glucokinase	Saccharomyces cerevisiae S288C	86-90
10595536-1	1999	Endo-beta-N-acetylglucosaminidase H hydrolyzes the beta-(1-4)-glycosidic link of the N,N"-diacetylchitobiose core of high-mannose and hybrid asparagine-linked oligosaccharides.	Mannose	122-129	O-GlcNAcase	Homo sapiens	5-33
10595536-1	1999	Endo-beta-N-acetylglucosaminidase H hydrolyzes the beta-(1-4)-glycosidic link of the N,N"-diacetylchitobiose core of high-mannose and hybrid asparagine-linked oligosaccharides.	Mannose	122-129	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	51-60
10529229-0	1999	Selective recognition of mannose by the human eosinophil Charcot-Leyden crystal protein (galectin-10): a crystallographic study at 1.8 A resolution.	Mannose	25-32	Charcot-Leyden crystal galectin	Homo sapiens	57-87
10529229-0	1999	Selective recognition of mannose by the human eosinophil Charcot-Leyden crystal protein (galectin-10): a crystallographic study at 1.8 A resolution.	Mannose	25-32	Charcot-Leyden crystal galectin	Homo sapiens	89-100
10529229-6	1999	Interestingly, the CLC protein demonstrates no affinity for beta-galactosides and binds mannose in a manner very different from those of other related galectins that have been shown to bind lactosamine.	Mannose	88-95	Charcot-Leyden crystal galectin	Homo sapiens	19-22
10559446-3	1999	Calreticulin carries two glycans of the typical ER high-mannose form.	Mannose	56-63	calreticulin	Homo sapiens	0-12
10559958-3	1999	Here we show that a cathepsin-Z-related glycoprotein binds to the recycling, mannose-specific membrane lectin ERGIC-53.	Mannose	77-84	lectin, mannose binding 1	Homo sapiens	110-118
10521541-0	1999	Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides.	Mannose	146-153	alpha-1,3-mannosyltransferase MNT2	Saccharomyces cerevisiae S288C	0-5
10521541-0	1999	Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides.	Mannose	146-153	alpha-1,3-mannosyltransferase MNT3	Saccharomyces cerevisiae S288C	10-15
10521541-0	1999	Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides.	Mannose	146-153	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	63-68
10521544-3	1999	The recombinant enzyme removes a single mannose residue from Man9GlcNAc and [1H]-NMR analysis indicates that the only product is Man8GlcNAc isomer B, the form lacking the middle-arm terminal alpha 1,2-mannose.	Mannose	40-47	mannosidase alpha class 1A member 1	Homo sapiens	61-65
10521544-5	1999	The properties and specificity of this human alpha 1,2-mannosidase are identical to the endoplasmic reticulum alpha 1,2-mannosidase from Saccharomyces cerevisiae and differ from those of previously cloned Golgi alpha 1,2-mannosidases that remove up to four mannose residues from Man9GlcNAc2 during N-glycan maturation.	Mannose	257-264	mannosidase alpha class 1A member 2	Homo sapiens	45-66
10521544-5	1999	The properties and specificity of this human alpha 1,2-mannosidase are identical to the endoplasmic reticulum alpha 1,2-mannosidase from Saccharomyces cerevisiae and differ from those of previously cloned Golgi alpha 1,2-mannosidases that remove up to four mannose residues from Man9GlcNAc2 during N-glycan maturation.	Mannose	257-264	mannosidase alpha class 1A member 2	Homo sapiens	110-131
10521535-0	1999	The sugar binding activity of MR60, a mannose-specific shuttling lectin, requires a dimeric state.	Mannose	38-45	lectin, mannose binding 1	Homo sapiens	30-34
10456901-3	1999	Rat SP-D but not rat SP-A bound the conidia, and the binding was inhibited by EDTA, mannose, glucose, maltose, and inositol.	Mannose	84-91	surfactant protein D	Rattus norvegicus	4-8
10456838-2	1999	Previously, we demonstrated that a hexose (mannose) or two amino sugars (glucosaminyl or galactosaminyl residues) when covalently conjugated to a protein backbone (neoglycoproteins) mimicked the mouse ZP3 glycoprotein and induced the AR in capacitated mouse spermatozoa (Loeser and Tulsiani, Biol Reprod 1999; 60:94-101).	Mannose	43-50	zona pellucida glycoprotein 3	Mus musculus	201-204
10460833-4	1999	The results revealed that VE-cadherin carries predominantly sialylated diantennary and hybrid-type glycans in addition to some triantennary and high mannose-type species.	Mannose	149-156	cadherin 5	Homo sapiens	26-37
10589993-1	1999	Two types of rat mannose-binding proteins (MBPs), MBP-A (serum type) and MBP-C (liver type), have similar binding specificity for monosaccharide and similar binding site construct according to the X-ray structure, but exhibit different affinity toward natural oligosaccharides and glycoproteins.	Mannose	17-24	mannose binding lectin 1	Rattus norvegicus	50-55
10461918-9	1999	This metabolic process strongly depends on the availability of glucose or mannose as hydride donors for the regeneration of the NADPH that is required for the reduction of GSSG by glutathione reductase.	Mannose	74-81	glutathione-disulfide reductase	Rattus norvegicus	180-201
10423401-3	1999	One large clone hybridized to both SP-A and SP-D cDNAs and was found by polymerase chain reaction (PCR) to contain sequences from one of the mouse mannose-binding lectin genes (Mbl1).	Mannose	147-154	mannose-binding lectin (protein A) 1	Mus musculus	177-181
10484609-4	1999	Steady-state and pulse-chase labeling experiments established that human HL was synthesized as an ER-associated precursor containing high mannose N-linked glycans.	Mannose	138-145	lipase C, hepatic type	Homo sapiens	73-75
10482662-3	1999	Furthermore, D-Man induced the release of cytochrome c from mitochondria.	Mannose	13-18	cytochrome c, somatic	Homo sapiens	42-54
10589993-3	1999	Binding of a number of mannose-containing di- and tri-saccharides and high-mannose type oligosaccharides indicated that MBP-C has an extended binding area of weak interaction with the second and the third mannose residues, whereas MBP-A recognizes just a single mannose residue.	Mannose	23-30	mannose binding lectin 2	Rattus norvegicus	120-125
10589993-1	1999	Two types of rat mannose-binding proteins (MBPs), MBP-A (serum type) and MBP-C (liver type), have similar binding specificity for monosaccharide and similar binding site construct according to the X-ray structure, but exhibit different affinity toward natural oligosaccharides and glycoproteins.	Mannose	17-24	mannose binding lectin 2	Rattus norvegicus	73-78
10589993-3	1999	Binding of a number of mannose-containing di- and tri-saccharides and high-mannose type oligosaccharides indicated that MBP-C has an extended binding area of weak interaction with the second and the third mannose residues, whereas MBP-A recognizes just a single mannose residue.	Mannose	75-82	mannose binding lectin 2	Rattus norvegicus	120-125
10406849-0	1999	Vesicular-integral membrane protein, VIP36, recognizes high-mannose type glycans containing alpha1--&gt;2 mannosyl residues in MDCK cells.	Mannose	60-67	lectin, mannose binding 2	Canis lupus familiaris	37-42
10589993-3	1999	Binding of a number of mannose-containing di- and tri-saccharides and high-mannose type oligosaccharides indicated that MBP-C has an extended binding area of weak interaction with the second and the third mannose residues, whereas MBP-A recognizes just a single mannose residue.	Mannose	75-82	mannose binding lectin 2	Rattus norvegicus	120-125
10589993-3	1999	Binding of a number of mannose-containing di- and tri-saccharides and high-mannose type oligosaccharides indicated that MBP-C has an extended binding area of weak interaction with the second and the third mannose residues, whereas MBP-A recognizes just a single mannose residue.	Mannose	75-82	mannose binding lectin 2	Rattus norvegicus	120-125
10589993-5	1999	These findings explain the higher affinity of MBP-C for natural high-mannose type oligosaccharides as compared to MBP-A.	Mannose	69-76	mannose binding lectin 2	Rattus norvegicus	46-51
10406849-3	1999	It was found that VIP36 recognizes high-mannose type glycans containing alpha1--&gt;2 Man residues and alpha-amino substituted asparagine.	Mannose	40-47	lectin, mannose binding 2	Homo sapiens	18-23
10406849-4	1999	The binding of Vip36 to high-mannose type glycans was independent of Ca(2+)and theoptimal condition was pH 6.0 at 37 degrees C. The concentration at which half inhibition of the binding by Man(7-9).GlcNAc(2).	Mannose	29-36	lectin, mannose binding 2	Homo sapiens	15-20
10406849-7	1999	These results indicate that VIP36 functions as an intracellular lectin recognizing glycoproteins which possess high-mannose type glycans, (Manalpha1--&gt;2)(2-4).Man(5).	Mannose	116-123	lectin, mannose binding 2	Homo sapiens	28-33
10457454-6	1999	Their glycoform patterns were highly similar except for the conspicuous decrease in quantity of four glycoforms in the ovalbumin containing less mannose, compared to that of the other with more mannose.	Mannose	145-152	ovalbumin (SERPINB14)	Gallus gallus	119-128
10423515-2	1999	The intrinsic fluorescence intensities of bovine pancreatic RNase A, bovine alpha-lactalbumin, and aromatic amino acids were markedly depressed in solutions (1 mM or so) of free N-glycans of both the high-mannose and complex types.	Mannose	205-212	ribonuclease pancreatic	Bos taurus	60-67
10423515-2	1999	The intrinsic fluorescence intensities of bovine pancreatic RNase A, bovine alpha-lactalbumin, and aromatic amino acids were markedly depressed in solutions (1 mM or so) of free N-glycans of both the high-mannose and complex types.	Mannose	205-212	lactalbumin alpha	Bos taurus	76-93
10409699-1	1999	We have isolated a full-length cDNA clone encoding a human alpha1, 2-mannosidase that catalyzes the first mannose trimming step in the processing of mammalian Asn-linked oligosaccharides.	Mannose	106-113	mannosidase alpha class 1A member 2	Homo sapiens	59-80
10456178-3	1999	A mannose rich precursor form of LH and FSH receptor is accumulated inside target cells.	Mannose	2-9	follicle stimulating hormone receptor	Homo sapiens	40-52
10383441-0	1999	Identification of amino acids that modulate mannose phosphorylation of mouse DNase I, a secretory glycoprotein.	Mannose	44-51	deoxyribonuclease I	Mus musculus	77-84
10408727-1	1999	The outer envelope glycoprotein (gp120) from subtypes A-E of HIV-1 was purified using a specific high mannose-binding lectin, Galanthus nivalis agglutinin.	Mannose	102-109	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	33-38
10422843-7	1999	These results suggest that flexibility is required for the adjustments of protein-protein contacts necessary for the phosphoryltransfer between the phosphorylcarrier protein HPr, IIA(Man), IIB(Man), and the incoming mannose bound to the transmembrane IIC(Man)-IID(Man) complex.	Mannose	216-223	haptoglobin-related protein	Homo sapiens	174-177
10472796-6	1999	A significant proportion of the labeled alpha1,2-mannosidase was immunoprecipitated by alpha1,6-mannose antibodies in wild-type, deltapep4 and rer1/deltapep4 cells with endogenous levels of alpha1,2-mannosidase, and in wild-type, deltapep4, rer1 and rer1/deltapep4 cells overexpressing alpha1,2-mannosidase.	Mannose	96-103	protein retrieval receptor	Saccharomyces cerevisiae S288C	143-147
10472797-3	1999	alpha-Mannosidases IA and IB trim Man9GlcNAc2 to Man5GlcNAc2, while alpha-mannosidase II acts after GlcNAc transferase I to remove two mannose residues from GlcNAcMan5GlcNAc2 to form GlcNAcMan3GlcNAc2 prior to extension into complex N-glycans by Golgi glycosyltransferases.	Mannose	135-142	mannosidase, alpha, class 2A, member 1	Rattus norvegicus	68-88
10353843-0	1999	Introduction of mannose binding protein-type phosphatidylinositol recognition into pulmonary surfactant protein A.	Mannose	16-23	surfactant protein A1	Homo sapiens	83-113
10208935-2	1999	This protein, designated gp250, was the sole viral glycoprotein detected in the culture medium after [3H]mannose labeling of the infected cells.	Mannose	105-112	sortilin related receptor 1	Homo sapiens	25-30
10342863-6	1999	Deglycosylation studies revealed that the higher-molecular-mass CRES proteins (19 and 17 kDa) were the result of N-linked glycosylation, caused by the presence of high mannose residues.	Mannose	168-175	cystatin 8 (cystatin-related epididymal spermatogenic)	Mus musculus	64-68
10233903-7	1999	Using an immunofluorescence staining procedure, cross-linking of CD66b induced the redistribution of CD11b on neutrophils with distinct areas of CD11b clustering via a process susceptible of inhibition by D-mannose.	Mannose	205-214	CEA cell adhesion molecule 8	Homo sapiens	65-70
10233903-7	1999	Using an immunofluorescence staining procedure, cross-linking of CD66b induced the redistribution of CD11b on neutrophils with distinct areas of CD11b clustering via a process susceptible of inhibition by D-mannose.	Mannose	205-214	integrin subunit alpha M	Homo sapiens	101-106
10233903-7	1999	Using an immunofluorescence staining procedure, cross-linking of CD66b induced the redistribution of CD11b on neutrophils with distinct areas of CD11b clustering via a process susceptible of inhibition by D-mannose.	Mannose	205-214	integrin subunit alpha M	Homo sapiens	145-150
10233903-9	1999	Such a type of interaction is presumably instrumental for neutrophil cytolytic activity in that the lysis was inhibited by D-mannose and enhanced by the MoAb VIM-12, which mimics the cooperation between CD11b and GPI-anchored molecules by specifically interacting with CD11b lectin-like sites.	Mannose	123-132	integrin subunit alpha M	Homo sapiens	203-208
10397151-9	1999	Electrospray ionisation mass spectrometry (ESMS) indicate that the N-glycans of baculovirus derived Fc gamma RIIa are core mannose oligosaccharide side chains.	Mannose	123-130	Fc gamma receptor IIa	Homo sapiens	100-113
10224141-10	1999	Expression studies of fusion proteins lacking the collagen and N-terminal domains produced in Escherichia coli affirmed that CL-L1 binds mannose weakly.	Mannose	137-144	collectin subfamily member 10	Homo sapiens	125-130
10390051-1	1999	A mannose-binding lectin was isolated from the blood serum of Atlantic salmon (Salmo salar).	Mannose	2-9	lectin	Salmo salar	18-24
10390051-7	1999	Binding experiments using biotinylated lectin revealed that it specifically recognizes and binds to mannose on the surfaces of two salmon pathogens, Vibrio anguillarum and Aeromonas salmonicida, implying an immunological role for this lectin in Atlantic salmon.	Mannose	100-107	lectin	Salmo salar	39-45
10390051-7	1999	Binding experiments using biotinylated lectin revealed that it specifically recognizes and binds to mannose on the surfaces of two salmon pathogens, Vibrio anguillarum and Aeromonas salmonicida, implying an immunological role for this lectin in Atlantic salmon.	Mannose	100-107	lectin	Salmo salar	235-241
10224226-3	1999	The MR is believed to mediate both endocytosis of glycoproteins and phagocytosis of microorganisms, which bear terminal mannose, fucose, N-acetylglucosamine, or glucose residues.	Mannose	120-127	mannose receptor C-type 1	Homo sapiens	4-6
10360417-3	1999	We propose that the sugar moiety structure of PSA which is increased in PCA is a multiantennary complex type with branched N-acetylglucosamine beta(1-&gt;4) mannose.	Mannose	157-164	kallikrein related peptidase 3	Homo sapiens	46-49
10191200-7	1999	Western blots and enzymatic digestions confirmed that the 284R protein is a glycoprotein, which contains only N-linked oligosaccharides, both high mannose (48 kDa) and complex types (67 kDa).	Mannose	147-154	284R	Bovine adenovirus 3	58-62
10216230-9	1999	These results indicate (1) the glucan-binding sugar chain of Tip1p is a GPI derivative, and (2) the GPI anchor is cleaved at the glycosyl moiety, and the resultant mannose reducing end is probably used to link Tip1p to cell wall glucan.	Mannose	164-171	putative lipase	Saccharomyces cerevisiae S288C	61-66
10216230-9	1999	These results indicate (1) the glucan-binding sugar chain of Tip1p is a GPI derivative, and (2) the GPI anchor is cleaved at the glycosyl moiety, and the resultant mannose reducing end is probably used to link Tip1p to cell wall glucan.	Mannose	164-171	putative lipase	Saccharomyces cerevisiae S288C	210-215
10328552-3	1999	The binding of MBL to these cell lines was sugar-specific and calcium-dependent, since it was almost completely inhibited in the presence of 10 mM EDTA or 50 mM mannose.	Mannose	161-168	mannose binding lectin 2	Homo sapiens	15-18
10085239-5	1999	Fructose, galactose, mannose, 2-deoxyglucose and xylitol were found to maintain the mRNA content of both AS and the glucose-regulated protein GRP78 in a state of repression, whereas 3-O-methylglucose did not.	Mannose	21-28	heat shock protein family A (Hsp70) member 5	Homo sapiens	142-147
10320038-7	1999	Although mannose-6-phosphorylated LPIP is increased 13-fold in brains of patients with JNCL, this form of LPIP did not have any enzyme activity.	Mannose	9-16	CLN3 lysosomal/endosomal transmembrane protein, battenin	Homo sapiens	87-91
10066452-2	1999	MBP activates the complement pathway through its interaction with mannose-rich carbohydrates on various microorganisms and a common opsonic defect has been shown to be associated with a low serum concentration of MBP.	Mannose	66-73	myelin basic protein	Homo sapiens	0-3
10217406-2	1999	Carbohydrate analysis revealed that the glycosylated moiety of rAch was composed of 50 mol mannose and 2 mol N-acetylglucosamine residues.	Mannose	91-98	acyl-CoA thioesterase 12	Rattus norvegicus	63-67
9920905-1	1999	Rat serum mannose-binding protein (MBP-A) functions as part of the innate immune system by targetting complement toward potentially pathogenic microorganisms.	Mannose	10-17	mannose binding lectin 1	Rattus norvegicus	35-40
10095773-1	1999	Shortly after synthesis, p58, the rat homologue of the mannose-binding lectin ERGIC-53/MR60, which localizes to pre-Golgi and cis-Golgi compartments, forms dimers and hexamers, after which an equilibrium of both forms is reached.	Mannose	55-62	lectin, mannose-binding, 1	Rattus norvegicus	25-28
10069839-0	1999	Mannose inhibits Arabidopsis germination via a hexokinase-mediated step.	Mannose	0-7	hexokinase	Arabidopsis thaliana	47-57
10026209-4	1999	Altered sedimentation of intracellular complexes following treatment with the specific proteasome inhibitor lactacystin, and in combination with mannosidase inhibition, revealed that the removal of mannose from attached oligosaccharides abrogates the release of misfolded alpha1-antitrypsin from calnexin prior to proteasomal degradation.	Mannose	198-205	serpin family A member 1	Homo sapiens	272-290
10026209-4	1999	Altered sedimentation of intracellular complexes following treatment with the specific proteasome inhibitor lactacystin, and in combination with mannosidase inhibition, revealed that the removal of mannose from attached oligosaccharides abrogates the release of misfolded alpha1-antitrypsin from calnexin prior to proteasomal degradation.	Mannose	198-205	calnexin	Homo sapiens	296-304
10026209-7	1999	A model is proposed in which the removal of mannose from multiple attached oligosaccharides directs calnexin in the selection of misfolded alpha1-antitrypsin for degradation by the proteasome.	Mannose	44-51	calnexin	Homo sapiens	100-108
10026209-7	1999	A model is proposed in which the removal of mannose from multiple attached oligosaccharides directs calnexin in the selection of misfolded alpha1-antitrypsin for degradation by the proteasome.	Mannose	44-51	serpin family A member 1	Homo sapiens	139-157
10188822-5	1999	RESULTS: The protein isolated by use of mannose affinity matrices was SP-D.	Mannose	40-47	surfactant protein D	Equus caballus	70-74
9837919-5	1998	In contrast, all of the TSHRs synthesized in mutant CHO-Lec1, 2, and 8 cells (mannose-rich, sialic acid-deficient, and galactose-deficient oligosaccharides, respectively) bound TSH and produced cAMP in response to TSH with an affinity and an EC50 similar to those in TSHR expressed in parental CHO cells (CHO-TSHR; sialylated oligosaccharides).	Mannose	78-85	thyrotropin receptor	Cricetulus griseus	24-28
9972879-0	1999	Delivery, distribution, and neuronal uptake of exogenous mannose-terminal glucocerebrosidase in the intact rat brain.	Mannose	57-64	glucosylceramidase beta	Rattus norvegicus	74-92
9878780-2	1999	alpha-Glucosidase I encoded by CWH41 cleaves the terminal alpha1, 2-linked glucose and alpha-glucosidase II encoded by ROT2 removes the two alpha1,3-linked glucose residues from the Glc3Man9GlcNAc2 oligosaccharide precursor while the alpha1,2-mannosidase encoded by MNS1 removes one specific mannose to form a single isomer of Man8GlcNAc2.	Mannose	292-299	mannosyl-oligosaccharide glucosidase	Saccharomyces cerevisiae S288C	31-36
9884406-4	1999	UDP- N- acetylglucosamine:alpha-3-d-mannoside beta-1, 2- N- acetylglucosaminyltransferase I (GnT-I) is essential for the conversion of high mannose-type N- glycans to hybrid- and complex-type ones.	Mannose	140-147	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	93-98
10082671-3	1999	A second, termed pH 1.3, containing myo-inositol glucosamine and mannose acted reciprocally to inhibit the cAMP-dependent protein kinase phosphorylation of INH-1 and DARPP-32 in a dose-dependent manner in the low micromolar range.	Mannose	65-72	protein phosphatase 1 regulatory inhibitor subunit 1A	Homo sapiens	156-161
10082671-3	1999	A second, termed pH 1.3, containing myo-inositol glucosamine and mannose acted reciprocally to inhibit the cAMP-dependent protein kinase phosphorylation of INH-1 and DARPP-32 in a dose-dependent manner in the low micromolar range.	Mannose	65-72	protein phosphatase 1 regulatory inhibitor subunit 1B	Homo sapiens	166-174
10048546-7	1999	RESULTS: Protein isolated by use of mannose-affinity matrices was identified as surfactant protein A (SP-A).	Mannose	36-43	pulmonary surfactant-associated protein A	Equus caballus	80-100
10048546-7	1999	RESULTS: Protein isolated by use of mannose-affinity matrices was identified as surfactant protein A (SP-A).	Mannose	36-43	pulmonary surfactant-associated protein A	Equus caballus	102-106
9892640-1	1999	Mannan-binding protein (MBP), a Ca2+-dependent mammalian lectin specific for mannose and N-acetylglucosamine, is an important serum component associated with innate immunity.	Mannose	77-84	myelin basic protein	Homo sapiens	0-22
9892640-1	1999	Mannan-binding protein (MBP), a Ca2+-dependent mammalian lectin specific for mannose and N-acetylglucosamine, is an important serum component associated with innate immunity.	Mannose	77-84	myelin basic protein	Homo sapiens	24-27
10190023-8	1999	As a glycoprotein, thyroglobulin contains 8-10% total carbohydrate with galactose, mannose, fucose, N-acetyl glucosamine and sialic acid residues.	Mannose	83-90	thyroglobulin	Homo sapiens	19-32
9990335-10	1998	The following differences were observed in KCS secreted mucins compared to normal samples: an increase in the proportion of mucin with low buoyant density; a decrease in mannose content detected with Concanavalin A lectin; an increase in N-acetylglucosamine structures detected with Lycopersicon esculentum lectin; increased migration and lack of evidence for distinct subunit structure on agarose gels.	Mannose	170-177	mucin	Canis lupus familiaris	56-61
9972491-17	1998	These results indicate that the terminal sequences of oligosaccharide side-chains in spermatocytes and, principally, in spermatids are: fucose, mannose, Neu5Ac2,3Gal1,3GalNAc, Gal1,3GalNAc, Gal1,4GlcNAc, Neu5AcGalNAc and GalNAc (in O-glycosylated proteins); mannose (in N-glycosylated proteins) and GlcNAc (in both protein types).	Mannose	258-265	galectin 1	Homo sapiens	176-180
9756928-0	1998	Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae.	Mannose	96-103	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	22-26
9851992-2	1998	The FLO1 gene, which encodes a cell wall protein, is considered to play an important role in yeast flocculation, which is inhibited by mannose but not by glucose (mannose-specific flocculation).	Mannose	135-142	flocculin FLO1	Saccharomyces cerevisiae S288C	4-8
9851992-2	1998	The FLO1 gene, which encodes a cell wall protein, is considered to play an important role in yeast flocculation, which is inhibited by mannose but not by glucose (mannose-specific flocculation).	Mannose	163-170	flocculin FLO1	Saccharomyces cerevisiae S288C	4-8
9851992-3	1998	A new homologue of FLO1, named Lg-FLO1, was isolated from a flocculent bottom-fermenting yeast strain in which flocculation is inhibited by both mannose and glucose (mannose/glucose-specific flocculation).	Mannose	145-152	flocculin FLO1	Saccharomyces cerevisiae S288C	19-23
9851992-3	1998	A new homologue of FLO1, named Lg-FLO1, was isolated from a flocculent bottom-fermenting yeast strain in which flocculation is inhibited by both mannose and glucose (mannose/glucose-specific flocculation).	Mannose	145-152	flocculin FLO1	Saccharomyces cerevisiae S288C	34-38
9851992-3	1998	A new homologue of FLO1, named Lg-FLO1, was isolated from a flocculent bottom-fermenting yeast strain in which flocculation is inhibited by both mannose and glucose (mannose/glucose-specific flocculation).	Mannose	166-173	flocculin FLO1	Saccharomyces cerevisiae S288C	19-23
9851992-3	1998	A new homologue of FLO1, named Lg-FLO1, was isolated from a flocculent bottom-fermenting yeast strain in which flocculation is inhibited by both mannose and glucose (mannose/glucose-specific flocculation).	Mannose	166-173	flocculin FLO1	Saccharomyces cerevisiae S288C	34-38
9851992-4	1998	In order to confirm that both FLO1 and Lg-FLO1 are involved in the yeast flocculation phenomenon, the FLO1 gene in the mannose-specific flocculation strain was replaced by the Lg-FLO1 gene.	Mannose	119-126	flocculin FLO1	Saccharomyces cerevisiae S288C	30-34
9851992-4	1998	In order to confirm that both FLO1 and Lg-FLO1 are involved in the yeast flocculation phenomenon, the FLO1 gene in the mannose-specific flocculation strain was replaced by the Lg-FLO1 gene.	Mannose	119-126	flocculin FLO1	Saccharomyces cerevisiae S288C	42-46
9851992-4	1998	In order to confirm that both FLO1 and Lg-FLO1 are involved in the yeast flocculation phenomenon, the FLO1 gene in the mannose-specific flocculation strain was replaced by the Lg-FLO1 gene.	Mannose	119-126	flocculin FLO1	Saccharomyces cerevisiae S288C	42-46
9851992-4	1998	In order to confirm that both FLO1 and Lg-FLO1 are involved in the yeast flocculation phenomenon, the FLO1 gene in the mannose-specific flocculation strain was replaced by the Lg-FLO1 gene.	Mannose	119-126	flocculin FLO1	Saccharomyces cerevisiae S288C	42-46
9815228-4	1998	Preincubation of yeasts with rabbit mannose-binding protein (MBP) resulted in dose-related enhancement of TNF-alpha secretion, through a Ca++-dependent pathway inhibited by D-mannose.	Mannose	173-182	myelin basic protein	Oryctolagus cuniculus	36-59
9815228-4	1998	Preincubation of yeasts with rabbit mannose-binding protein (MBP) resulted in dose-related enhancement of TNF-alpha secretion, through a Ca++-dependent pathway inhibited by D-mannose.	Mannose	173-182	myelin basic protein	Oryctolagus cuniculus	61-64
9815228-4	1998	Preincubation of yeasts with rabbit mannose-binding protein (MBP) resulted in dose-related enhancement of TNF-alpha secretion, through a Ca++-dependent pathway inhibited by D-mannose.	Mannose	173-182	tumor necrosis factor	Oryctolagus cuniculus	106-115
9883672-0	1998	[VIP36 recognizes high-mannose type glycans in relation to apical membrane traffic].	Mannose	23-30	lectin, mannose binding 2	Homo sapiens	1-6
9828106-4	1998	We conclude that bovine alveolar macrophages expose binding sites for SP-A that are specific and that depend on Ca2+ and on mannose residues.	Mannose	124-131	pulmonary surfactant-associated protein A	Bos taurus	70-74
9828106-9	1998	From the fractionated and blotted proteins of the receptor preparation two proteins bound SP-A in a Ca2+-dependent manner, a 40-kDa protein showing mannose dependency and a 210-kDa protein, showing no mannose sensitivity.	Mannose	148-155	pulmonary surfactant-associated protein A	Bos taurus	90-94
9851992-5	1998	The transformant in which the Lg-FLO1 gene was incorporated showed the same flocculation phenotype as the mannose/glucose-specific flocculation strain, suggesting that the FLO1 and Lg-FLO1 genes encode mannose-specific and mannose/glucose-specific lectin-like proteins, respectively.	Mannose	106-113	flocculin FLO1	Saccharomyces cerevisiae S288C	172-176
9851992-5	1998	The transformant in which the Lg-FLO1 gene was incorporated showed the same flocculation phenotype as the mannose/glucose-specific flocculation strain, suggesting that the FLO1 and Lg-FLO1 genes encode mannose-specific and mannose/glucose-specific lectin-like proteins, respectively.	Mannose	106-113	flocculin FLO1	Saccharomyces cerevisiae S288C	172-176
9851992-5	1998	The transformant in which the Lg-FLO1 gene was incorporated showed the same flocculation phenotype as the mannose/glucose-specific flocculation strain, suggesting that the FLO1 and Lg-FLO1 genes encode mannose-specific and mannose/glucose-specific lectin-like proteins, respectively.	Mannose	202-209	flocculin FLO1	Saccharomyces cerevisiae S288C	33-37
9851992-5	1998	The transformant in which the Lg-FLO1 gene was incorporated showed the same flocculation phenotype as the mannose/glucose-specific flocculation strain, suggesting that the FLO1 and Lg-FLO1 genes encode mannose-specific and mannose/glucose-specific lectin-like proteins, respectively.	Mannose	202-209	flocculin FLO1	Saccharomyces cerevisiae S288C	172-176
9851992-5	1998	The transformant in which the Lg-FLO1 gene was incorporated showed the same flocculation phenotype as the mannose/glucose-specific flocculation strain, suggesting that the FLO1 and Lg-FLO1 genes encode mannose-specific and mannose/glucose-specific lectin-like proteins, respectively.	Mannose	202-209	flocculin FLO1	Saccharomyces cerevisiae S288C	172-176
9851992-5	1998	The transformant in which the Lg-FLO1 gene was incorporated showed the same flocculation phenotype as the mannose/glucose-specific flocculation strain, suggesting that the FLO1 and Lg-FLO1 genes encode mannose-specific and mannose/glucose-specific lectin-like proteins, respectively.	Mannose	202-209	flocculin FLO1	Saccharomyces cerevisiae S288C	33-37
9851992-5	1998	The transformant in which the Lg-FLO1 gene was incorporated showed the same flocculation phenotype as the mannose/glucose-specific flocculation strain, suggesting that the FLO1 and Lg-FLO1 genes encode mannose-specific and mannose/glucose-specific lectin-like proteins, respectively.	Mannose	202-209	flocculin FLO1	Saccharomyces cerevisiae S288C	172-176
9851992-5	1998	The transformant in which the Lg-FLO1 gene was incorporated showed the same flocculation phenotype as the mannose/glucose-specific flocculation strain, suggesting that the FLO1 and Lg-FLO1 genes encode mannose-specific and mannose/glucose-specific lectin-like proteins, respectively.	Mannose	202-209	flocculin FLO1	Saccharomyces cerevisiae S288C	172-176
9832639-1	1998	Mannan binding protein (MBP) is a C-type lectin and has a high affinity to mannose and N-acetyl glucosamine.	Mannose	75-82	myelin basic protein	Homo sapiens	0-22
9832639-1	1998	Mannan binding protein (MBP) is a C-type lectin and has a high affinity to mannose and N-acetyl glucosamine.	Mannose	75-82	myelin basic protein	Homo sapiens	24-27
9863582-1	1998	This study set out to investigate whether plasma mannose-binding protein (MBP) deficiency caused by mutations in the MBP gene associates with pyogenic or opportunistic infections in HIV-infected patients.	Mannose	49-56	myelin basic protein	Homo sapiens	74-77
9779815-10	1998	We suggest that the prosequence of myeloperoxidase participates in the intracellular routing of the precursor and that this routing operates on precursors bearing mannose-rich rather than terminally glycosylated oligosaccharides and diverts them from the secretory pathway at a site proximal to the monensin-sensitive compartment of the Golgi apparatus.	Mannose	163-170	myeloperoxidase	Cricetulus griseus	35-50
9756928-0	1998	Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae.	Mannose	96-103	alpha-1,2-mannosyltransferase MNN5	Saccharomyces cerevisiae S288C	31-35
9756928-2	1998	In the mutants mnn2 and mnn5, the addition of the first and second of these two mannoses, respectively, is defective.	Mannose	80-88	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	15-19
9756928-2	1998	In the mutants mnn2 and mnn5, the addition of the first and second of these two mannoses, respectively, is defective.	Mannose	80-88	alpha-1,2-mannosyltransferase MNN5	Saccharomyces cerevisiae S288C	24-28
9726975-0	1998	Structural analysis of sequences O-linked to mannose reveals a novel Lewis X structure in cranin (dystroglycan) purified from sheep brain.	Mannose	45-52	dystroglycan 1	Homo sapiens	98-110
9771885-3	1998	Oligosaccharide chains, containing N-acetylglucosamine, mannose, galactose and sialic acid were found on recombinant gp51-p30.	Mannose	56-63	centromere protein V	Homo sapiens	122-125
9748349-8	1998	The complete glycan core structure (Man3-GluN) of typical GPI anchors including a mannose side chain and the inositolphosphate moiety was required for maximal insulin-mimetic activity of the PIG compounds with some variations possible with respect to the type of residues coupled to the terminal mannose/inositol as well as the type of linkages involved.	Mannose	82-89	insulin	Sus scrofa	159-166
9726975-4	1998	Mannose-linked Lewis X is the latest in an increasing list of oligosaccharide recognition "tags" that have been shown to be expressed on cranin (dystroglycan) purified from brain.	Mannose	0-7	dystroglycan 1	Homo sapiens	145-157
9694859-0	1998	Lysine-based structure responsible for selective mannose phosphorylation of cathepsin D and cathepsin L defines a common structural motif for lysosomal enzyme targeting.	Mannose	49-56	cathepsin D	Homo sapiens	76-87
9737720-4	1998	The accumulation of c-fos, JunB, and nur-77 mRNA occurs at physiological concentrations of glucose (3 to 11 mM), requires a 1-2 h period, and is mimicked by other nutrient stimuli including mannose, leucine plus glutamine, and pyruvate.	Mannose	190-197	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	20-25
9737720-4	1998	The accumulation of c-fos, JunB, and nur-77 mRNA occurs at physiological concentrations of glucose (3 to 11 mM), requires a 1-2 h period, and is mimicked by other nutrient stimuli including mannose, leucine plus glutamine, and pyruvate.	Mannose	190-197	nuclear receptor subfamily 4, group A, member 1	Rattus norvegicus	37-43
9746360-5	1998	Our results indicate that the asparagine-linked oligosaccharides of rat liver cathepsin L are of the oligomannose type, having two to six mannose residues.	Mannose	106-113	cathepsin L	Rattus norvegicus	78-89
9972287-2	1998	Glucose, mannose, fructose, glyceraldehyde and dihydroxyacetone all at 8 mM, significantly enhanced the release of insulin elicited by basal concentrations of these carbohydrates (2 mM).	Mannose	9-16	insulin	Homo sapiens	115-122
9724629-0	1998	DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate.	Mannose	50-57	dolichyl-phosphate mannosyltransferase subunit 2, regulatory	Homo sapiens	0-4
9724629-0	1998	DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate.	Mannose	50-57	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	132-136
9694859-0	1998	Lysine-based structure responsible for selective mannose phosphorylation of cathepsin D and cathepsin L defines a common structural motif for lysosomal enzyme targeting.	Mannose	49-56	cathepsin L	Homo sapiens	92-103
9694859-2	1998	In this study, the involvement of specific lysine residues in mannose phosphorylation of cathepsin D was explored by site-directed mutagenesis.	Mannose	62-69	cathepsin D	Homo sapiens	89-100
9680411-2	1998	Glycosylation of the derived acceptor with reactive groups only at C-6 with an ortho ester of d-mannose proceeded smoothly in dichloromethane in the presence of trimethylsilyl trifluoromethanesulfonate, and the degree of branching was up to 0.6.	Mannose	94-103	complement C6	Homo sapiens	67-70
9700129-5	1998	This effect was abolished by the presence of 100 mM mannose (for SP-A) or maltose (for SP-D) in the culture medium, which suggested that the CRD regions of SP-A and SP-D may interact with the carbohydrate structures on the surface molecules of lymphocytes.	Mannose	52-59	surfactant protein A1	Homo sapiens	65-69
9700129-5	1998	This effect was abolished by the presence of 100 mM mannose (for SP-A) or maltose (for SP-D) in the culture medium, which suggested that the CRD regions of SP-A and SP-D may interact with the carbohydrate structures on the surface molecules of lymphocytes.	Mannose	52-59	surfactant protein A1	Homo sapiens	156-160
9700129-5	1998	This effect was abolished by the presence of 100 mM mannose (for SP-A) or maltose (for SP-D) in the culture medium, which suggested that the CRD regions of SP-A and SP-D may interact with the carbohydrate structures on the surface molecules of lymphocytes.	Mannose	52-59	surfactant protein D	Homo sapiens	165-169
9639537-1	1998	Cells synthesize the GPI anchor carbohydrate core by successively adding N-acetylglucosamine, three mannoses, and phosphoethanolamine (EtN-P) onto phosphatidylinositol, thus forming the complete GPI precursor lipid which is then added to proteins.	Mannose	100-108	glucose-6-phosphate isomerase	Homo sapiens	21-24
9639537-2	1998	Previously, we isolated a GPI deficient yeast mutant accumulating a GPI intermediate containing only two mannoses, suggesting that it has difficulty in adding the third, alpha1,2-linked Man of GPI anchors.	Mannose	105-113	glucose-6-phosphate isomerase	Homo sapiens	26-29
9639537-2	1998	Previously, we isolated a GPI deficient yeast mutant accumulating a GPI intermediate containing only two mannoses, suggesting that it has difficulty in adding the third, alpha1,2-linked Man of GPI anchors.	Mannose	105-113	glucose-6-phosphate isomerase	Homo sapiens	68-71
9639537-2	1998	Previously, we isolated a GPI deficient yeast mutant accumulating a GPI intermediate containing only two mannoses, suggesting that it has difficulty in adding the third, alpha1,2-linked Man of GPI anchors.	Mannose	105-113	glucose-6-phosphate isomerase	Homo sapiens	68-71
9679138-1	1998	ERGIC-53, a homo-oligomeric recycling protein associated with the ER-Golgi intermediate compartment (ERGIC), has properties of a mannose-selective lectin in vitro, suggesting that it may function as a transport receptor for glycoproteins in the early secretory pathway.	Mannose	129-136	lectin, mannose binding 1	Homo sapiens	0-8
9603208-5	1998	Experiments using two deglycosylating enzymes, N-glycopeptidase F and endoglycosidase H, clearly indicated that the 103.5-kDa species represented a partially unglycosylated form of GluR2/3 subunits containing the high-mannose type of oligosaccharide moiety, whereas receptors present in synaptosomal fractions were composed of subunits with complex oligosaccharides.	Mannose	218-225	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	181-186
9715405-1	1998	N-Acetylglucosaminyltransferase III (GnT III) catalyses the addition of N-acetylglucosamine through a beta 1-4 linkage to the mannose of the trimannosyl core, resulting in conversion of the concanavalin A (Con A)-reactive glycan into a non-reactive state.	Mannose	126-133	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-35
9715405-1	1998	N-Acetylglucosaminyltransferase III (GnT III) catalyses the addition of N-acetylglucosamine through a beta 1-4 linkage to the mannose of the trimannosyl core, resulting in conversion of the concanavalin A (Con A)-reactive glycan into a non-reactive state.	Mannose	126-133	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	37-44
9684549-2	1998	Dissociation ions specific to stereochemical differences at C2 and C4 in hexose complexes are observed in the MS2 and MS3 spectra, thus allowing unambiguous differentiation of glucose, galactose, mannose, and talose.	Mannose	196-203	MS2	Homo sapiens	110-113
9684549-2	1998	Dissociation ions specific to stereochemical differences at C2 and C4 in hexose complexes are observed in the MS2 and MS3 spectra, thus allowing unambiguous differentiation of glucose, galactose, mannose, and talose.	Mannose	196-203	MS3	Homo sapiens	118-121
9618082-2	1998	Variants of the mannose-binding lectin (MBL) gene have been suggested to predispose to HIV-1 infection.	Mannose	16-23	mannose binding lectin 2	Homo sapiens	40-43
9665336-7	1998	In contrast, normal sperm mannose receptor expression was seen in five men whose abnormal progesterone receptor expression/function and inability to acrosome react after mannose treatment were correlated with their reduced fertility in vitro.	Mannose	26-33	progesterone receptor	Homo sapiens	90-111
9665336-8	1998	In conclusion, surface progesterone receptor aggregation enhances the mannose ligand-stimulated acrosome reaction.	Mannose	70-77	progesterone receptor	Homo sapiens	23-44
9569229-3	1998	The gene encoding human alpha1-antitrypsin (A1AT) was delivered to macrophages in vitro and in vivo by targeting the mannose receptor with mannose-terminal molecular conjugates.	Mannose	117-124	serpin family A member 1	Homo sapiens	24-42
9569229-3	1998	The gene encoding human alpha1-antitrypsin (A1AT) was delivered to macrophages in vitro and in vivo by targeting the mannose receptor with mannose-terminal molecular conjugates.	Mannose	117-124	serpin family A member 1	Homo sapiens	44-48
9881749-2	1998	The monosaccharide composition of MGp showed only mannose, N-acetylglucosamine and a small amount of galactose.	Mannose	50-57	matrix Gla protein	Homo sapiens	34-37
9497351-4	1998	The accumulated effect of these changes is to alter the ligand binding selectivity of the domain so that it resembles E- or P-selectin more closely than it resembles the parental mannose-binding domain.	Mannose	179-186	selectin P	Homo sapiens	124-134
9525910-8	1998	In accordance with these observations, we demonstrated that the glycolytic substrates glucose, mannose, and fructose, as well as the gluconeognic substrates glycerol and dihydroxyacetone, increased the concentration of GR mRNA in primary cultures of hepatocytes from fed rats.	Mannose	95-102	glucagon receptor	Rattus norvegicus	219-221
9529088-7	1998	Hapten inhibition assays with monosaccharides and defined oligosaccharides showed that the inhibitory effects of MBP were abrogated by mannose or high-mannose type oligomannose-oligosaccharide.	Mannose	135-142	myelin basic protein	Homo sapiens	113-116
9529088-8	1998	The latter carbohydrate is the ligand of the 40-kDa glycoprotein of C. trachomatis L2, which is known to mediate attachment, suggesting that the MBP binds to high mannose moieties on the surface of chlamydial organisms.	Mannose	163-170	myelin basic protein	Homo sapiens	145-148
9531299-3	1998	We had previously shown that IgG1 Abs produced in the cell line Lec 1, which attaches a high-mannose intermediate carbohydrate, were severely deficient in complement activation, showed a slightly reduced affinity for Fc gammaRI, and had a reduced in vivo half-life.	Mannose	93-100	LOC105243590	Mus musculus	29-33
9531299-7	1998	While IgG1-Lec 2 was essentially identical to wild type in its capacity to interact with individual components of the classical complement activation pathway, IgG1-Lec 8 demonstrated equivalent maximal binding at lower concentrations and was preferentially bound by mannose-binding protein.	Mannose	266-273	LOC105243590	Mus musculus	159-163
9555075-7	1998	However, when the O-oligosaccharides from the wild type and ldb1 were compared, we found a significant decrease in the tetrasaccharide in the latter, as well as a concomitant increase in the disaccharide, suggesting a defect in the Kre2p/Mnt1p involved in the transfer of the third mannose of these residues.	Mannose	282-289	Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1	Saccharomyces cerevisiae S288C	60-64
9554988-11	1998	However, there were significant differences in the rate of lactate production between the DG and CA3 areas during application of 3 mM glucose, 10 mM mannose and 10 mM fructose.	Mannose	149-156	carbonic anhydrase 3	Cavia porcellus	97-100
9500786-4	1998	For CD3-delta, we describe a process leading to its degradation that includes trimming of mannose residues from asparagine-linked (N-linked) oligosaccharides, generation of ubiquitinated membrane-bound intermediates, and proteasome-dependent removal from the ER membrane.	Mannose	90-97	CD3 delta subunit of T-cell receptor complex	Homo sapiens	4-13
9490653-3	1998	SP-A belongs to the family of collagenous C-type lectins along with mannose binding protein (MBP) and SP-D, both of which have also been mapped to the long arm of chromosome 10.	Mannose	68-75	surfactant protein A1	Homo sapiens	0-4
9559545-4	1998	Besides the core carbohydrates, variable numbers of mannose outer chains were also added to some of the secreted alpha 1-AT.	Mannose	52-59	serpin family A member 1	Homo sapiens	113-123
9559545-5	1998	The human alpha 1-AT secreted in both methylotrophic yeasts was also heterogeneous and hypermannosylated as observed in S. cerevisiae, although the overall length of mannose outer chains of alpha 1-AT in the methylotrophic yeasts appeared to be relatively shorter than those of alpha 1-AT in S. cerevisiae.	Mannose	166-173	serpin family A member 1	Homo sapiens	10-20
9490653-3	1998	SP-A belongs to the family of collagenous C-type lectins along with mannose binding protein (MBP) and SP-D, both of which have also been mapped to the long arm of chromosome 10.	Mannose	68-75	myelin basic protein	Homo sapiens	93-96
9480908-7	1998	Finally, total levels of serum mannose 6-phosphorylated glycoproteins were approximately 45-fold and approximately 15-fold higher than wild type in CI- and CD-MPR-deficient mice respectively, and there were specific differences in the pattern of these proteins when comparing CI- and CD-MPR deficient animals.	Mannose	31-38	mannose-6-phosphate receptor, cation dependent	Mus musculus	156-162
9492274-9	1998	Both intact and trypsin digests of the high-mannose-type oligosaccharide-containing glycoproteins ribonuclease B and ovalbumin had a low affinity (Ki 0.5-1.5 microM) for the mannose receptor.	Mannose	44-51	mannose receptor C-type 1	Homo sapiens	174-190
9468538-9	1998	Intracellular pro-MPO has high mannose oligosaccharide side chains, whereas stored mature MPO was found to have both high mannose and complex oligosaccharide side chains as judged by only partial sensitivity to endoglycosidase H. The propeptide may normally interfere with the generation of certain complex oligosaccharide chain(s) supported by the finding of high mannose side chains in secreted pro-MPO and lack of them in MPODeltapro that contained complex oligosaccharide side chains only.	Mannose	122-129	myeloperoxidase	Homo sapiens	90-93
9468538-9	1998	Intracellular pro-MPO has high mannose oligosaccharide side chains, whereas stored mature MPO was found to have both high mannose and complex oligosaccharide side chains as judged by only partial sensitivity to endoglycosidase H. The propeptide may normally interfere with the generation of certain complex oligosaccharide chain(s) supported by the finding of high mannose side chains in secreted pro-MPO and lack of them in MPODeltapro that contained complex oligosaccharide side chains only.	Mannose	122-129	myeloperoxidase	Homo sapiens	90-93
9871687-1	1998	N-phenyl-carbamate of D-mannonohydroxymolactone (I) was synthesized from mannose and was shown to be the best competitive inhibitor of beta-mannosidase so far reported (Ki = 25 nM).	Mannose	73-80	mannosidase beta	Homo sapiens	135-151
9452447-4	1998	High levels (8-20 mM) of fructose and mannose (but not galactose or L-glucose) also inhibit the release of IL-1 activity, suggesting that metabolism is required for IL-1 inhibition.	Mannose	38-45	interleukin 1 complex	Mus musculus	107-111
9452447-4	1998	High levels (8-20 mM) of fructose and mannose (but not galactose or L-glucose) also inhibit the release of IL-1 activity, suggesting that metabolism is required for IL-1 inhibition.	Mannose	38-45	interleukin 1 complex	Mus musculus	165-169
9675357-1	1998	cis-1,2-Stannylene acetals of D-mannose and L-rhamnose, formed preferentially from the free sugars treated with dibutyltin oxide, are capable of displacing the trifluoromethanesulfonyl (triflyl) leaving groups in carbohydrates to give, with retention of configuration at the anomeric center in the nucleophile, cis-1,2-linked oligosaccharides.	Mannose	30-39	cytokine inducible SH2 containing protein	Homo sapiens	0-5
9675357-1	1998	cis-1,2-Stannylene acetals of D-mannose and L-rhamnose, formed preferentially from the free sugars treated with dibutyltin oxide, are capable of displacing the trifluoromethanesulfonyl (triflyl) leaving groups in carbohydrates to give, with retention of configuration at the anomeric center in the nucleophile, cis-1,2-linked oligosaccharides.	Mannose	30-39	cytokine inducible SH2 containing protein	Homo sapiens	311-316
9973639-6	1998	Partially glycosylated Rh50 (32 kDa) was again isolated from the lysates of K562 cells metabolically labeled with [35S]-methionine or [3H]-mannose using anti-Rh50 antisera.	Mannose	139-146	Rh associated glycoprotein	Homo sapiens	23-27
18020553-3	1998	The enzyme, alglucerase, is glucocerebrosidase derived from human placental tissue; its oligosaccharide chain has been modified to expose terminal mannose residues, facilitating uptake in macrophages.	Mannose	147-154	glucosylceramidase beta	Homo sapiens	12-23
9762360-5	1998	The effect of glucose on translocation is mimicked by mannose which is also phosphorylated by glucokinase as well as by competitive inhibitors of glucokinase (mannoheptulose and 5-thioglucose) which are not phosphorylated.	Mannose	54-61	glucokinase	Homo sapiens	94-105
18470493-2	1998	BothD: -xylose andD: -mannose reduce the cell water content andD: -galactose does occasionally the same but onlyD: -xylose reduces significantly the intracellular sodium concentration, presumably by forming steric hindrances at the outlets of the sodium pumps at the outer surface of the cell membrane.	Mannose	22-29	secretion associated Ras related GTPase 1B	Homo sapiens	60-64
9442926-6	1997	The concentration of mannose (38 +/- 60 micrograms/mg protein) in alpha 2-macroglobulin derived from SLE patients was significantly higher than normal donors (mannose, 4.8 +/- 1 micrograms/mg protein) however, the concentration of glucose in alpha 2-macroglobulin derived from SLE patients when compared to normal donors was not statistically significant, 18 +/- 20 micrograms/mg protein in SLE versus 2 +/- 0.5 micrograms/mg protein in normal donors due to high variation between samples.	Mannose	21-28	alpha-2-macroglobulin	Homo sapiens	242-263
9801926-6	1998	The interleukin-10-increased fluorescein-labelled-dextran endocytosis was mostly mediated via the mannose receptor, as unlabelled mannose and specific antimannose receptor monoclonal antibody inhibited most of the uptake.	Mannose	98-105	interleukin 10	Homo sapiens	4-18
21374492-5	1998	Gp120 oligosaccharides are a mixture of high mannose-, hybrid-, and complex-type N-glycans (3-5).	Mannose	45-52	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	0-5
9453405-6	1998	In RPT cells grown under SHAKE conditions, HSP70 synthesis was detected 1 h after heat stress and decreased below detection by 3 h. In contrast, the uptake of radiolabeled mannose into (glycoprotein) GP62 (Mr 62,000), GP50, and GP38 was observed in control SHAKE cultures and was not further increased after heat stress.	Mannose	172-179	tumor associated calcium signal transducer 2	Homo sapiens	218-222
9453405-6	1998	In RPT cells grown under SHAKE conditions, HSP70 synthesis was detected 1 h after heat stress and decreased below detection by 3 h. In contrast, the uptake of radiolabeled mannose into (glycoprotein) GP62 (Mr 62,000), GP50, and GP38 was observed in control SHAKE cultures and was not further increased after heat stress.	Mannose	172-179	podoplanin	Homo sapiens	228-232
9447247-9	1997	Reaction of r-vWF with carbohydrate-specific lectins demonstrated that r-vWF contained a high proportion of N-glycans composed of mannose, galactose, glucose, N-acetylglucosamine and terminal sialic acid.	Mannose	130-137	von Willebrand factor	Homo sapiens	73-76
9442926-5	1997	Since the interaction of peptide fragments derived from alpha 2-macroglobulin with Con A requires the presence of mannose and/or glucose residues, we have also examined if there are any correlations between the levels of mannose and glucose in alpha 2-macroglobulin and SLE.	Mannose	114-121	alpha-2-macroglobulin	Homo sapiens	56-77
9442926-6	1997	The concentration of mannose (38 +/- 60 micrograms/mg protein) in alpha 2-macroglobulin derived from SLE patients was significantly higher than normal donors (mannose, 4.8 +/- 1 micrograms/mg protein) however, the concentration of glucose in alpha 2-macroglobulin derived from SLE patients when compared to normal donors was not statistically significant, 18 +/- 20 micrograms/mg protein in SLE versus 2 +/- 0.5 micrograms/mg protein in normal donors due to high variation between samples.	Mannose	21-28	alpha-2-macroglobulin	Homo sapiens	66-87
9441811-4	1997	Native SOD and modified SOD with mannose (Man-SOD) or galactose (Gal-SOD) were intravenously given just prior to reperfusion of the grafted liver.	Mannose	33-40	superoxide dismutase 1	Homo sapiens	24-27
9640845-9	1997	CONCLUSION: MBP binds to immune complexes consisting of IgG and IgM-RF, and probably recognizes either the mannose moiety of IgM-RF or the N-acetyl-glucosamine of agalactosyl IgG.	Mannose	107-114	myelin basic protein	Homo sapiens	12-15
9359879-6	1997	Corresponding to these changes in cell structure, rhodopsin transport was blocked between the rER and the Golgi body, as indicated by the accumulation of immature rhodopsin carrying a large high-mannose-type oligosaccharide chain.	Mannose	195-202	neither inactivation nor afterpotential E	Drosophila melanogaster	50-59
9441811-4	1997	Native SOD and modified SOD with mannose (Man-SOD) or galactose (Gal-SOD) were intravenously given just prior to reperfusion of the grafted liver.	Mannose	33-40	superoxide dismutase 1	Homo sapiens	24-27
9441811-4	1997	Native SOD and modified SOD with mannose (Man-SOD) or galactose (Gal-SOD) were intravenously given just prior to reperfusion of the grafted liver.	Mannose	33-40	superoxide dismutase 1	Homo sapiens	24-27
9350059-1	1997	Human B-cell glucokinase displays sigmoidal kinetics towards D-glucose or D-mannose, but fails to do so towards D-fructose.	Mannose	74-83	glucokinase	Homo sapiens	13-24
9378972-8	1997	NK cell Fc gamma RIIIa is glycosylated with high mannose- and complex-type oligosaccharides, while monocyte Fc gamma RIIIa has no high mannose-type oligosaccharides.	Mannose	49-56	Fc gamma receptor IIIa	Homo sapiens	8-22
9368610-6	1997	The rMAFA was found to bind specifically terminal mannose residues in a Ca(2+)-dependent manner.	Mannose	50-57	MAF bZIP transcription factor A	Rattus norvegicus	4-9
9362376-6	1997	The cluster mannoside with six mannose residues connected with a backbone of five lysine groups (M6L5) was, like unlabeled t-PA, able to inhibit 125I-t-PA degradation in the nmol/L range, while the mannoside M5L4 inhibited 125I-t-PA degradation in the micromol/L range.	Mannose	31-38	plasminogen activator, tissue type	Homo sapiens	123-127
9362376-6	1997	The cluster mannoside with six mannose residues connected with a backbone of five lysine groups (M6L5) was, like unlabeled t-PA, able to inhibit 125I-t-PA degradation in the nmol/L range, while the mannoside M5L4 inhibited 125I-t-PA degradation in the micromol/L range.	Mannose	31-38	plasminogen activator, tissue type	Homo sapiens	150-154
9362376-6	1997	The cluster mannoside with six mannose residues connected with a backbone of five lysine groups (M6L5) was, like unlabeled t-PA, able to inhibit 125I-t-PA degradation in the nmol/L range, while the mannoside M5L4 inhibited 125I-t-PA degradation in the micromol/L range.	Mannose	31-38	plasminogen activator, tissue type	Homo sapiens	150-154
9343171-5	1997	Late isolates were shown to be much more sensitive than early strains to neutralization by the mouse serum mannose-binding lectin (MBL) and rat lung surfactant protein D (SP-D) and bound greater levels of these lectins in enzyme-linked immunosorbent assays and Western blot analyses.	Mannose	107-114	mannose-binding lectin (protein C) 2	Mus musculus	131-134
9367184-6	1997	As a result, it was revealed that the Tg fraction eluted at higher ionic strength from a DEAE-cellulose column is apt to contain more of each iodoamino acid, as well as total content of iodine, larger negative zeta-potential, conforming to sialic acid content in the Tg molecule and to a higher content of di-sialo-bi-antennary complex and to high mannose type oligosaccharides.	Mannose	348-355	thyroglobulin	Homo sapiens	38-40
16728190-7	1997	This fluorescence was inhibited in the presence of 0.2 M D-mannose, a competitive sugar, suggesting that FITC-ConA binds specifically to glycocomponents on the inner acrosomal membrane.	Mannose	57-66	CONA	Bos taurus	110-114
9395260-3	1997	Sperm surface mannose lectins can be visualized by their ability to bind a synthetic model zona ligand, fluorescein isothiocyanate (FITC)-conjugated mannosylated bovine serum albumin (BSA) (Man-FITC-BSA).	Mannose	14-21	albumin	Homo sapiens	169-188
9395260-3	1997	Sperm surface mannose lectins can be visualized by their ability to bind a synthetic model zona ligand, fluorescein isothiocyanate (FITC)-conjugated mannosylated bovine serum albumin (BSA) (Man-FITC-BSA).	Mannose	14-21	albumin	Homo sapiens	184-187
9395260-5	1997	In our assay, the addition of mM amounts of mannose monosaccharide to Man-FITC-BSA increases the number of polyvalent mannose ligands bound by individual spermatozoa and increases the rate of the acrosome reactions induced by Man-FITC-BSA, thereby increasing specimen processing efficiency.	Mannose	44-51	albumin	Homo sapiens	79-82
9395260-5	1997	In our assay, the addition of mM amounts of mannose monosaccharide to Man-FITC-BSA increases the number of polyvalent mannose ligands bound by individual spermatozoa and increases the rate of the acrosome reactions induced by Man-FITC-BSA, thereby increasing specimen processing efficiency.	Mannose	44-51	albumin	Homo sapiens	235-238
9300722-0	1997	Induction of TNF-alpha in human peripheral blood mononuclear cells by the mannoprotein of Cryptococcus neoformans involves human mannose binding protein.	Mannose	129-136	tumor necrosis factor	Homo sapiens	13-22
10453527-5	1997	Human EPO protein with highly mannose glycosylated was identified by Western blot methods in both secreted and in cells proteins.	Mannose	30-37	erythropoietin	Homo sapiens	6-9
9350282-2	1997	SAP exhibits multispecific calcium-dependent binding to oligosaccharides with terminal N-acetyl-galactosamine, mannose and glucuronic acid.	Mannose	111-118	amyloid P component, serum	Homo sapiens	0-3
9350282-8	1997	Of several monosaccharides tested only D-mannose interfered with SAP"s inhibition of both HA and infectivity.	Mannose	39-48	amyloid P component, serum	Homo sapiens	65-68
9350282-10	1997	The results indicate that the inhibition by SAP is due to steric effects when SAP binds to terminal mannose on oligosaccharides localized close to the sialic acid-binding site of the HA trimer.	Mannose	100-107	amyloid P component, serum	Homo sapiens	44-47
9350282-10	1997	The results indicate that the inhibition by SAP is due to steric effects when SAP binds to terminal mannose on oligosaccharides localized close to the sialic acid-binding site of the HA trimer.	Mannose	100-107	amyloid P component, serum	Homo sapiens	78-81
9287314-2	1997	Mannose in N-linked oligosaccharides is assumed to be derived primarily from glucose through phosphomannose isomerase (PMI).	Mannose	0-7	mannose phosphate isomerase	Homo sapiens	93-117
9287314-2	1997	Mannose in N-linked oligosaccharides is assumed to be derived primarily from glucose through phosphomannose isomerase (PMI).	Mannose	0-7	mannose phosphate isomerase	Homo sapiens	119-122
9287314-12	1997	PMI may normally be used to catabolize excess mannose rather than to primarily supply Man-6-P for glycoprotein synthesis.	Mannose	46-53	mannose phosphate isomerase	Homo sapiens	0-3
9300722-9	1997	Removal of human mannose binding protein (hMBP) by preincubation of serum with a specific mAb abrogated TNF-alpha induction by MP2 and strongly inhibited its binding to PBMCs.	Mannose	17-24	myelin basic protein	Homo sapiens	42-46
9300722-9	1997	Removal of human mannose binding protein (hMBP) by preincubation of serum with a specific mAb abrogated TNF-alpha induction by MP2 and strongly inhibited its binding to PBMCs.	Mannose	17-24	tumor necrosis factor	Homo sapiens	104-113
9300722-9	1997	Removal of human mannose binding protein (hMBP) by preincubation of serum with a specific mAb abrogated TNF-alpha induction by MP2 and strongly inhibited its binding to PBMCs.	Mannose	17-24	tryptase pseudogene 1	Homo sapiens	127-130
9376178-8	1997	Mannose (20 mM), a substrate of GK, and sorbitol (1 mM), a stimulator of glucose phosphorylation by GK, induced the translocation of GK from the nucleus to the cytoplasm in the presence of 5 mM glucose.	Mannose	0-7	glucokinase	Rattus norvegicus	32-34
9292005-4	1997	gp110 from all sources possessed a high-mannose type of N-glycosylation implying that gp110 has not passed through the Golgi.	Mannose	40-47	ADRM1 26S proteasome ubiquitin receptor	Homo sapiens	0-5
9276464-8	1997	The loss of three mannoses at the alpha-1,6-branch also reduced the Och1p activity.	Mannose	18-26	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	68-73
9276464-9	1997	These results suggest that Och1p is an initiation specific alpha-1,6-mannosyltransferase that requires the intact structure of Man8GlcNAc for efficient mannose outer chain initiation.	Mannose	152-159	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	27-32
9276464-9	1997	These results suggest that Och1p is an initiation specific alpha-1,6-mannosyltransferase that requires the intact structure of Man8GlcNAc for efficient mannose outer chain initiation.	Mannose	152-159	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	59-88
9315725-1	1997	Mannose-binding protein (MBP) belongs to the collectin subgroup of C-type lectins with specificity for mannose and N-acetylglucosamine sugars.	Mannose	103-110	myelin basic protein	Rattus norvegicus	0-23
9315725-1	1997	Mannose-binding protein (MBP) belongs to the collectin subgroup of C-type lectins with specificity for mannose and N-acetylglucosamine sugars.	Mannose	103-110	myelin basic protein	Rattus norvegicus	25-28
9271309-2	1997	Surfactant protein A (SP-A) is a nonimmune opsonin present in the alveolar spaces that binds carbohydrate residues such as mannose.	Mannose	123-130	surfactant associated protein A1	Mus musculus	22-26
12572434-3	1997	By gas chromatography analysis, LOK composes of rhamnose, arabinose, xylose, mannose, glucose and galactose.	Mannose	77-84	serine/threonine kinase 10	Homo sapiens	32-35
9201957-6	1997	Substitutions of negatively charged (Glu195, Glu202, and Asp215) and polar residues (Asn214) of the CRD with alanine but not substitution of the Arg197 with glycine reduced the binding of SP-A to mannose-Sepharose beads and to MSG.	Mannose	196-203	surfactant protein A1	Rattus norvegicus	188-192
9234817-2	1997	This strain exhibited plasmid (pO42)-encoded D-mannose-resistant hemagglutinating activity (MRHA) that was detected only at low temperatures (e.g., 0 degrees C) and only with human erythrocytes.	Mannose	45-54	ERC2 intronic transcript 1	Homo sapiens	31-35
9230118-1	1997	Rat liver mannose-binding protein (MBP-C) is the smallest known member of the collectin family of animal lectins, many of which are involved in defence against microbial pathogens.	Mannose	10-17	mannose binding lectin 2	Rattus norvegicus	35-40
9182588-3	1997	Examination of the electrophoretic mobility of a specifically O-linked protein from mutants and an analysis of their total O-linked mannosyl chains demonstrates that Ktr1p, Ktr3p, and Kre2p/Mnt1p have overlapping roles and collectively add most of the second and the third alpha1,2-linked mannose residues on O-linked oligosaccharides.	Mannose	289-296	alpha-1,2-mannosyltransferase KTR1	Saccharomyces cerevisiae S288C	166-171
9182588-3	1997	Examination of the electrophoretic mobility of a specifically O-linked protein from mutants and an analysis of their total O-linked mannosyl chains demonstrates that Ktr1p, Ktr3p, and Kre2p/Mnt1p have overlapping roles and collectively add most of the second and the third alpha1,2-linked mannose residues on O-linked oligosaccharides.	Mannose	289-296	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	184-189
9182588-3	1997	Examination of the electrophoretic mobility of a specifically O-linked protein from mutants and an analysis of their total O-linked mannosyl chains demonstrates that Ktr1p, Ktr3p, and Kre2p/Mnt1p have overlapping roles and collectively add most of the second and the third alpha1,2-linked mannose residues on O-linked oligosaccharides.	Mannose	289-296	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	190-195
9177294-5	1997	Thus, the presence of sialic acid containing mannose-rich carbohydrate moiety near the antigen binding site of a monoclonal antibody Fab fragment is relevant for defining antibody specificity.	Mannose	45-52	FA complementation group B	Homo sapiens	133-136
9184829-9	1997	In addition, Ibd1 synthesizes a truncated and unbranched outer chain lacking any alpha (1,2) linked mannoses attached to the alpha (1,6) linear backbone.	Mannose	100-108	Bfa1p	Saccharomyces cerevisiae S288C	13-17
9168976-4	1997	Analysis of the carbohydrate chains by BioGel P4 showed that thyroglobulin secreted in the presence of the Ca(2+)-perturbants displayed an increased ratio high mannose/complex chains.	Mannose	160-167	thyroglobulin	Rattus norvegicus	61-74
9186272-10	1997	The mannose structures detected on the proteins by lectins and localization after expression in the cells suggest that only the N-terminal TG fragment (containing the SP) is directed to the endoplasmatic reticulum but is unable to reach the Golgi complex.	Mannose	4-11	thyroglobulin	Homo sapiens	139-141
9127488-5	1997	In contrast with glycoproteins produced in Saccharomyces cerevisiae, our results with specific mannosidase digestions were consistent with previous studies showing that (alpha 1,3)-linked mannose residues were not present in extensions of the core Man8GN2 unit.	Mannose	188-195	transcriptional co-activator mating type protein alpha	Saccharomyces cerevisiae S288C	170-179
9145794-14	1997	The insulin-like growth factor-II receptor ligand complex is likely internalized via a pathway possibly related to mannose-phosphorylated residues as the insulin-like growth factor-II/mannose-6-phosphate receptor has been implicated in the intracellular targeting of lysosomal proteins containing glycosylated residues.	Mannose	115-122	insulin-like growth factor 2	Rattus norvegicus	4-33
9145794-14	1997	The insulin-like growth factor-II receptor ligand complex is likely internalized via a pathway possibly related to mannose-phosphorylated residues as the insulin-like growth factor-II/mannose-6-phosphate receptor has been implicated in the intracellular targeting of lysosomal proteins containing glycosylated residues.	Mannose	115-122	insulin-like growth factor 2	Rattus norvegicus	154-183
9169093-0	1997	Oral ingestion of mannose elevates blood mannose levels: a first step toward a potential therapy for carbohydrate-deficient glycoprotein syndrome type I. Carbohydrate-deficient glycoprotein syndrome type I (CDGS) is an inherited metabolic disorder with multisystemic abnormalities resulting from a failure to add entire N-linked oligosaccharide chains to many glycoproteins.	Mannose	18-25	phosphomannomutase 2	Homo sapiens	207-211
9169093-3	1997	We find that ingested mannose is efficiently absorbed and increases blood mannose levels in both normal subjects and CDGS patients.	Mannose	22-29	phosphomannomutase 2	Homo sapiens	117-121
9169093-3	1997	We find that ingested mannose is efficiently absorbed and increases blood mannose levels in both normal subjects and CDGS patients.	Mannose	74-81	phosphomannomutase 2	Homo sapiens	117-121
9169093-5	1997	Peak blood mannose concentrations occurred at 1-2 h following ingestion and the clearance half-time was approximately 4 h. Doses of 0.1 g mannose/ kg body weight given at 3-h intervals maintained blood mannose concentrations at levels 3- to 5-fold higher than the basal level in both normal controls (approximately 55 microM) and CDGS patients.	Mannose	138-145	phosphomannomutase 2	Homo sapiens	330-334
9169093-5	1997	Peak blood mannose concentrations occurred at 1-2 h following ingestion and the clearance half-time was approximately 4 h. Doses of 0.1 g mannose/ kg body weight given at 3-h intervals maintained blood mannose concentrations at levels 3- to 5-fold higher than the basal level in both normal controls (approximately 55 microM) and CDGS patients.	Mannose	138-145	phosphomannomutase 2	Homo sapiens	330-334
9169093-7	1997	These results establish the feasibility of using mannose as a potential therapeutic dietary supplement (nutraceutical) to treat CDGS patients.	Mannose	49-56	phosphomannomutase 2	Homo sapiens	128-132
9101419-10	1997	It allowed one to isolate two groups of apolipoprotein H molecules bearing biantennary and truncated hybrids and high mannose and hybrid oligosaccharides.	Mannose	118-125	apolipoprotein H	Homo sapiens	40-56
9101419-11	1997	Since Con A affinity chromatography allows fractionation of molecules differing in the extent of carbohydrate branching irrespective of the sialyl residues, we can conclude that mannose residues are masked with other sugars such as galactose-beta (1-4)N-acetylglucosamine, galactose-beta (1-3)N-acetyl-galactosamine and sialic acid linked alpha (2-6) to galactose or to N-acetylgalactosamine, or capped with sulfated residues.	Mannose	178-185	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	242-251
9101419-11	1997	Since Con A affinity chromatography allows fractionation of molecules differing in the extent of carbohydrate branching irrespective of the sialyl residues, we can conclude that mannose residues are masked with other sugars such as galactose-beta (1-4)N-acetylglucosamine, galactose-beta (1-3)N-acetyl-galactosamine and sialic acid linked alpha (2-6) to galactose or to N-acetylgalactosamine, or capped with sulfated residues.	Mannose	178-185	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	283-292
9101419-12	1997	Thus, according to our results apolipoprotein H presents truncated hybryd or hybrid-type carbohydrate chains which bear few unmasked mannose residues as terminal sugar.	Mannose	133-140	apolipoprotein H	Homo sapiens	31-47
9133645-3	1997	Cat-SOD exhibited an excellent inhibitory effect on superoxide anion release from the macrophages, and this effect surpassed those of native SOD and SOD modified with mannose (Man-SOD) which is taken up via mannose receptor-mediated endocytosis by macrophages.	Mannose	167-174	superoxide dismutase 1	Homo sapiens	4-7
9815705-6	1997	Brief periods of exposure ( approximately 30 min) to SPA at the IC50 for growth increased incorporation of [3H]mannose.	Mannose	111-118	surfactant protein A2	Homo sapiens	53-56
9147059-2	1997	We found that the liver-type MBP CRD of rat (MBP-C) bound methyl glycosides of certain mannobioses and -trioses, which are part of the mannose-rich N-glycoside, more tightly than methyl alpha-mannopyranoside.	Mannose	135-142	mannose binding lectin 2	Rattus norvegicus	45-50
9147059-5	1997	From these and other data, we postulate that the binding site of MBP-C has an extended area of interaction, probably the size of a mannotriose, while MBP-A interacts essentially with one mannose residue.	Mannose	187-194	mannose binding lectin 2	Homo sapiens	65-70
9147059-5	1997	From these and other data, we postulate that the binding site of MBP-C has an extended area of interaction, probably the size of a mannotriose, while MBP-A interacts essentially with one mannose residue.	Mannose	187-194	mannose binding lectin 1	Rattus norvegicus	150-155
9126611-8	1997	N-linked oligosaccharide profiling of purified VV and BV WT and S582A mutant hCox-2 showed the presence of high mannose structures, (Man)n (GlcNAc)2, n = 9, 8, 7, 6.	Mannose	112-119	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	77-83
9155088-7	1997	Lectin blotting indicated that cathepsin D is a glycoprotein which is recognized by Galanthus nivalis agglutinin and concanavalin A, suggesting the presence of mannose residues.	Mannose	160-167	cathepsin D	Homo sapiens	31-42
9060831-2	1997	MR is involved in removal of effete cells, phagocytosis of mannose-coated particles, pinocytosis, and antigen presentation.	Mannose	59-66	mannose receptor C-type 1	Homo sapiens	0-2
9074491-4	1997	The mannan-binding protein fraction of bovine serum that eluted with 100 mM mannose from a mannan-Sepharose column was analyzed under reducing conditions by SDS-PAGE.	Mannose	76-83	mannose binding lectin 2	Bos taurus	4-26
9038318-6	1997	Antisense oligodeoxynucleotide (ODN) to mannose receptor (MR) mRNA inhibited the expression and function of MR in macrophages as determined by Western blot analysis and 125I-labeled mannose-bovine serum albumin (BSA) binding, and also inhibited the elevation of cytokine IL-1beta, IL-6, and GM-CSF mRNA levels induced by C. albicans attachment.	Mannose	40-47	interleukin 1 beta	Mus musculus	271-279
9038318-6	1997	Antisense oligodeoxynucleotide (ODN) to mannose receptor (MR) mRNA inhibited the expression and function of MR in macrophages as determined by Western blot analysis and 125I-labeled mannose-bovine serum albumin (BSA) binding, and also inhibited the elevation of cytokine IL-1beta, IL-6, and GM-CSF mRNA levels induced by C. albicans attachment.	Mannose	40-47	interleukin 6	Mus musculus	281-285
9038318-6	1997	Antisense oligodeoxynucleotide (ODN) to mannose receptor (MR) mRNA inhibited the expression and function of MR in macrophages as determined by Western blot analysis and 125I-labeled mannose-bovine serum albumin (BSA) binding, and also inhibited the elevation of cytokine IL-1beta, IL-6, and GM-CSF mRNA levels induced by C. albicans attachment.	Mannose	40-47	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	291-297
9038211-8	1997	Although the high mannose 73-kDa species is capable of binding LH/hCG, our results show that post-translational processing in the Golgi is required for the mature 92-kDa receptor to reach the cell surface.	Mannose	18-25	chorionic gonadotropin subunit beta 5	Homo sapiens	66-69
9202426-0	1997	Arylsulfatase A from human placenta possesses only high mannose-type glycans.	Mannose	56-63	arylsulfatase A	Homo sapiens	0-15
9202426-7	1997	The results indicated that 97% of the arylsulfatase A oligosaccharides were low molecular weight high mannose type glycans possessing up to 5 mannose residues.	Mannose	102-109	arylsulfatase A	Homo sapiens	38-53
9202426-7	1997	The results indicated that 97% of the arylsulfatase A oligosaccharides were low molecular weight high mannose type glycans possessing up to 5 mannose residues.	Mannose	142-149	arylsulfatase A	Homo sapiens	38-53
9202426-10	1997	The remaining 3% of the arylsulfatase A oligosaccharides were of the high mannose type, possessing more than 5 mannose residues.	Mannose	74-81	arylsulfatase A	Homo sapiens	24-39
9202426-10	1997	The remaining 3% of the arylsulfatase A oligosaccharides were of the high mannose type, possessing more than 5 mannose residues.	Mannose	111-118	arylsulfatase A	Homo sapiens	24-39
9202426-13	1997	This study, of arylsulfatase A oligosaccharides separated from the protein part, shows that all glycans of the enzyme from human placenta are of the high mannose type.	Mannose	154-161	arylsulfatase A	Homo sapiens	15-30
9092938-7	1997	Mutagenesis of the glutamine residue at position 244 in the homologous region of alpha-glucosidase to proline results in a protein that is neither transported to the lysosomes nor secreted extracellularly but accumulates in the ER, intermediate compartment and cis-Golgi as a mannose-rich polypeptide similar to mutant sucrase-isomaltase in phenotype II.	Mannose	276-283	sucrase-isomaltase	Homo sapiens	81-98
9030589-3	1997	The GM2AP precursor is synthesized as an 18-kDa peptide, which is singly glycosylated, resulting in 22-kDa high mannose and 24-27-kDa complex glycoforms.	Mannose	112-119	ganglioside GM2 activator	Homo sapiens	4-9
9038177-12	1997	Sequence comparisons with other mannose/GlcNAc-specific C-type CRDs suggest that use of a stacking interaction in the binding of these sugars is probably unique to CRD-4 of the mannose receptor.	Mannose	32-39	mannose receptor C-type 1	Homo sapiens	177-193
9056417-8	1997	This is in line with the finding that the intracellular transport APN is unaffected by the absence of O-glycosylation or by changes in N-glycosylation as the various glycosylated forms of aminopeptidase N are normally converted from the high-mannose form to the complex glycosylated form.	Mannose	242-249	alanyl aminopeptidase, membrane	Homo sapiens	188-204
9061364-2	1997	UDP-N-acetylglucosamine:beta-D-mannoside beta 1-4 N-acetylglucosaminyltransferase III (GlcNAc-TIII, EC2.4.1.144) catalyzes the addition of GlcNAc to the mannose that is itself beta 1-4 linked to underlying N-acetylglucosamine.	Mannose	153-160	mannoside acetylglucosaminyltransferase 3	Mus musculus	87-98
9033386-1	1997	Rat serum mannose-binding protein in which residues 211-213 have been changed to the Lys-Lys-Lys sequence found in E-selectin binds HL-60 cells and the oligosaccharide 3"-NeuAc-Le(x).	Mannose	10-17	selectin E	Homo sapiens	115-125
9020857-9	1997	The enzymes have similar substrate specificities and utilize mannose, methyl-alpha-mannoside, alpha-1,2-mannobiose and methyl-alpha-1,2-mannobiose, as well as Man15-30GlcNAc, derived from mnn2 mutant glycoproteins, as substrates.	Mannose	61-68	alpha-1,2-mannosyltransferase MNN2	Saccharomyces cerevisiae S288C	188-192
8952699-6	1996	The biochemical properties of this isoform are consistent with it being an N-linked glycosylated form of the AR precursor that contains unprocessed mannose residues.	Mannose	148-155	amphiregulin	Homo sapiens	109-111
8943261-13	1996	32PO4 labeling revealed that the glycosylation mutants of ASM were phosphorylated predominantly at mannose residues of oligosaccharides linked to N-84, N-333, and N-393.	Mannose	99-106	sphingomyelin phosphodiesterase 1, acid lysosomal	Mus musculus	58-61
8943270-2	1996	GdA has high mannose-, hybrid-, and complex-type biantennary oligosaccharides including structures with fucosylated or sialylated N, N"-diacetyllactosediamine (GalNAcbeta1-4GlcNAc) sequences, which are rare in other human glycoproteins.	Mannose	13-20	progestagen associated endometrial protein	Homo sapiens	0-3
9027354-4	1996	They allow to observe the existence of two forms of the FSH receptor in the ovaries: a major approximately 87 kDa species corresponding to the mature receptor and a minor approximately 81 kDa species corresponding to a high mannose rich precursor.	Mannose	224-231	follicle stimulating hormone receptor	Homo sapiens	56-68
9032886-5	1996	We found that the antigenicity of the complex form of E2 protein was greater than that of the high-mannose form of E2 protein.	Mannose	99-106	ubiquitin conjugating enzyme E2 B	Homo sapiens	115-125
8977632-2	1996	METHODS: The interaction between AGP-glycoforms and their receptor is a lectin-like interaction confirmed by inhibition of the binding by mannose and N-Acetyl-D-glucosamine.	Mannose	138-145	orosomucoid 1	Rattus norvegicus	33-36
8910412-1	1996	In search of synthetic high affinity ligands for the mannose receptor, we synthesized a series of lysine-based oligomannosides containing two (M2L) to six (M6L5) terminal alpha-D-mannose groups that are connected with the backbone by flexible elongated spacers (16 A).	Mannose	178-186	mannose receptor C-type 1	Homo sapiens	53-69
8920947-8	1996	Mannose also inhibited the expression of MT1-MMP mRNA induced by ConA.	Mannose	0-7	matrix metallopeptidase 14	Homo sapiens	41-48
8955886-1	1996	The serum mannan-binding protein (S-MBP) is a Ca(2+)-dependent C-type animal lectin specific for mannose and N-acetylglucosamine, which plays an important role in first-line host defense.	Mannose	97-104	transmembrane 9 superfamily member 3	Homo sapiens	4-32
8955886-1	1996	The serum mannan-binding protein (S-MBP) is a Ca(2+)-dependent C-type animal lectin specific for mannose and N-acetylglucosamine, which plays an important role in first-line host defense.	Mannose	97-104	transmembrane 9 superfamily member 3	Homo sapiens	34-39
8958059-1	1996	Macrophage phagocytic activity has previously been shown to be increased by binding of modified alpha 2-macroglobulin (alpha 2M) with mannose residues at termini of sugar chains to mannose receptors on macrophages, with a subsequent increase in the number of Fc gamma receptors at the cell surface.	Mannose	134-141	alpha-2-macroglobulin	Ovis aries	96-117
8918452-1	1996	The transfer of mannose to seryl and threonyl residues of secretory proteins is catalyzed by a family of protein mannosyltransferases coded for by seven genes (PMT1-7).	Mannose	16-23	dolichyl-phosphate-mannose-protein mannosyltransferase PMT1	Saccharomyces cerevisiae S288C	160-164
8958059-1	1996	Macrophage phagocytic activity has previously been shown to be increased by binding of modified alpha 2-macroglobulin (alpha 2M) with mannose residues at termini of sugar chains to mannose receptors on macrophages, with a subsequent increase in the number of Fc gamma receptors at the cell surface.	Mannose	134-141	alpha-2-macroglobulin	Ovis aries	119-127
8958059-3	1996	The phagocytosis of IgG-opsonized sheep red blood cells through the action of the Fc gamma receptor by modified alpha 2M was inhibited by mannose and herbimycin A and slightly so by genistein.	Mannose	138-145	alpha-2-macroglobulin	Ovis aries	112-120
9293085-1	1996	The mannose-resistant hemagglutinating factor (HAF) was extracted and purified from a diffuse adherent Escherichia coli (DAEC) strain belonging to the classic enteropathogenic E. coli (EPEC) serotype (0128).	Mannose	4-11	coagulation factor XII	Homo sapiens	47-50
8876135-5	1996	The glycoprotein product of US3 (gpUS3) occurs mostly in a high-mannose form and coimmunoprecipitates with beta 2-microglobulin associated class I heavy chains.	Mannose	64-71	membrane glycoprotein US3	Human betaherpesvirus 5	28-31
8898075-5	1996	On the other hand, the recognition site of FAb 8 apparently consisted of two alpha-1,2-linked oligomannosyl side chains and an alpha-1,6-linked mannose residue that originated from the mannan backbone, Man(alpha)1 --&gt; 2Man(alpha)1 --&gt; 2(Man(alpha)1 --&gt;2Man(alpha)1 --&gt; 6)Man.	Mannose	144-151	FA complementation group B	Homo sapiens	43-46
8863485-10	1996	These results suggest that SP receptors on the human astrocytoma cell line U-87 MG have either a biantennary complex-type or a high mannose-type of carbohydrate chain and may be regulated by GTP-binding protein(s).	Mannose	132-139	tachykinin precursor 1	Homo sapiens	27-29
8845033-8	1996	Both tick salivary gland extracts and D-mannose inhibited IL-2 production by these lymphocytes.	Mannose	38-47	interleukin 2	Mus musculus	58-62
8780401-1	1996	A potential role for the macrophage mannose receptor in human monocyte-derived macrophage fusion was explored by testing the effects of previously described inhibitors of its activity on the formation of interleukin-4-induced foreign body giant cells in vitro Giant cell formation was prevented or reduced in the presence of alpha-man-nan and synthetic neoglycoprotein conjugates according to the following pattern of relative inhibition: mannose-bovine serum albumin (BSA) &gt; N-acetylgucosamine-BSA congruent to glucose-BSA.	Mannose	36-43	interleukin 4	Homo sapiens	204-217
8905625-5	1996	Mannose and fructose, but not galactose, prevented the induction of GRP78 and accumulation of the abnormal GLUT1.	Mannose	0-7	heat shock protein family A (Hsp70) member 5	Homo sapiens	68-73
8905625-5	1996	Mannose and fructose, but not galactose, prevented the induction of GRP78 and accumulation of the abnormal GLUT1.	Mannose	0-7	solute carrier family 2 member 1	Homo sapiens	107-112
8806782-5	1996	On the other hand, an increase in the .NO/O2.- value resulted in nitration of SP-A tyrosine residues, located in the carbohydrate recognition domain (CRD), and decreased the ability of SP-A to aggregate lipids and bind mannose, two functions that require an intact CRD.	Mannose	219-226	surfactant protein A1	Homo sapiens	78-82
8806782-0	1996	Nitration of surfactant protein A (SP-A) tyrosine residues results in decreased mannose binding ability.	Mannose	80-87	surfactant protein A1	Homo sapiens	13-33
8806782-0	1996	Nitration of surfactant protein A (SP-A) tyrosine residues results in decreased mannose binding ability.	Mannose	80-87	surfactant protein A1	Homo sapiens	35-39
8806782-5	1996	On the other hand, an increase in the .NO/O2.- value resulted in nitration of SP-A tyrosine residues, located in the carbohydrate recognition domain (CRD), and decreased the ability of SP-A to aggregate lipids and bind mannose, two functions that require an intact CRD.	Mannose	219-226	surfactant protein A1	Homo sapiens	185-189
8806782-11	1996	However, ONOO., formed by the reaction of .NO and O2.-, nitrates SP-A leading to decreased ability to aggregate lipids and bind mannose.	Mannose	128-135	surfactant protein A1	Homo sapiens	65-69
8797833-8	1996	The alpha-1,6-mannosyltransferase also transferred the alpha-1,6-linked branching mannose unit to the mannan of Saccharomyces cerevisiae.	Mannose	82-89	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	4-33
8880976-7	1996	D-mannose binds mainly to Fc rather than CD18 receptors, and decreased Agg-IgG induced [Ca2+]i and the chemiluminescent response of neutrophils.	Mannose	0-9	integrin subunit beta 2	Bos taurus	41-45
8702831-2	1996	The kinase is quite specific for GalNAc as the phosphate acceptor and is inactive with GlcNAc, ManNAc, glucose, galactose, mannose, GalN, and GlcN.	Mannose	123-130	galanin and GMAP prepropeptide	Homo sapiens	33-37
8888433-9	1996	Both mucin fractions had altered glycosylation patterns: augmentation of beta-galactose, alpha-N-acetyl galactosamine, and mannose coincided with a decrease in alpha-fucose.	Mannose	123-130	solute carrier family 13 member 2	Rattus norvegicus	5-10
8761451-3	1996	Here we demonstrate that IL-2 is a calcium-independent lectin specific for oligomannosidic N-glycans with five and six mannose residues.	Mannose	119-126	interleukin 2	Homo sapiens	25-29
8861954-0	1996	PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor.	Mannose	122-129	phosphatidylinositol glycan anchor biosynthesis class B	Sus scrofa	0-5
8861954-3	1996	We cloned a human gene termed PIG-B (phosphatidylinositol glycan of complementation class B) that is involved in transferring the third mannose.	Mannose	136-143	phosphatidylinositol glycan anchor biosynthesis class B	Sus scrofa	30-35
8690123-8	1996	Sperm agglutination mediated by type IV mucin mAb 33.3 was abrogated completely by D-mannose.	Mannose	83-92	LOC100508689	Homo sapiens	40-45
8878985-0	1996	The entrapment of mannose-terminated glucocerebrosidase (Alglucerase) in human carrier erythrocytes.	Mannose	18-25	glucosylceramidase beta	Homo sapiens	57-68
8864829-6	1996	Carbohydrate analysis of the recombinant hTPO showed that the protein is glycosylated and mannose is the major oligosaccharide.	Mannose	90-97	thyroid peroxidase	Homo sapiens	41-45
8757998-4	1996	Uncleaved gp 130 remained completely sensitive to endo-beta-N-acetylglucosaminidase H (Endo-H) in untreated cells following long chase periods, indicating high-mannose oligosaccharides at all of the 18 N-linked glycosylation sites (Asn-X-Ser/Thr) and retention in the endoplasmic reticulum.	Mannose	160-167	Neutrophil migration (granulocyte glycoprotein)	Homo sapiens	10-16
8832204-7	1996	Mutant pro-LPH-mact lacking the complete transmembrane domain persists as a monomeric, mannose-rich and transport-incompetent molecule that is not secreted into the exterior milieu, accumulates most likely in the ER and is ultimately degraded.	Mannose	87-94	lactase	Homo sapiens	11-14
8757998-6	1996	The heavily glycosylated N-terminal gp93 subunit was not detected by [35S]methionine-labelling but was easily detected along with gp55 after labelling with [3H]mannose.	Mannose	160-167	neuroplastin	Homo sapiens	130-134
8679719-3	1996	Likewise, there were obvious discrepancies between the kinetics of glucose, mannose and fructose phosphorylation by B-cell glucokinase, e.g. in terms of maximal velocity, and the secretory and metabolic responses to these hexoses in intact islets.	Mannose	76-83	glucokinase	Homo sapiens	123-134
8698510-8	1996	The median mannose-sensitive adherence to HT-29 cells was lower for isolates from IgA-deficient individuals than from the controls (9 versus 26 bacteria per cell, P &lt; 0.05).	Mannose	11-18	CD79a molecule	Homo sapiens	82-85
9162528-0	1996	D-mannose dimer introduced human recombinant interleukin- 1 alpha, NEO IL-1 alpha, exhibits altered tissue distribution in mice.	Mannose	2-9	interleukin 1 alpha	Homo sapiens	45-65
8647071-0	1996	Quantitative analysis of the targeting of mannose-terminal glucocerebrosidase.	Mannose	42-49	glucosylceramidase beta	Rattus norvegicus	59-77
8647071-4	1996	Gaucher"s disease is treated by intravenous administration of a modified glucocerebrosidase (Alglucerase), which has exposed mannose residues to promote uptake by target macrophages.	Mannose	125-132	glucosylceramidase beta	Rattus norvegicus	73-91
8645185-5	1996	The K(m) and Ki values for 2-deoxy-D-glucose, D-glucose, D-mannose and D-galactose were 3.7 mM, 2.6 mM, 11 mM and 30 mM respectively, similar to the values for GLUT 1 expressed in mammalian cells.	Mannose	57-66	solute carrier family 2 member 1	Homo sapiens	160-166
8670743-9	1996	Mannose and N-acetyl-glucosamine are major carbohydrate monomers of the oligosaccaride chains of human rhodopsin, and a relatively high percentage of the oligosaccharide chains are galactosylated.	Mannose	0-7	rhodopsin	Homo sapiens	103-112
9162528-0	1996	D-mannose dimer introduced human recombinant interleukin- 1 alpha, NEO IL-1 alpha, exhibits altered tissue distribution in mice.	Mannose	2-9	interleukin 1 alpha	Homo sapiens	71-81
8833334-0	1996	Effect of the quantity and linkage position of mannose (alpha 1,2) residues in capillary gel electrophoresis of high-mannose-type oligosaccharides.	Mannose	47-54	adrenoceptor alpha 1D	Homo sapiens	56-65
8722088-3	1996	Of the three fractions, the amount of TPS-1 accounted for over 60% of total yield of ECP, which was a predominant polysaccharide consisting of arabinose (Ara), mannose (Man) and galactose (Gal) as major neutral monosaccharides.	Mannose	160-167	tryptase alpha/beta 1	Homo sapiens	38-43
8868475-0	1996	ERGIC-53 is a functional mannose-selective and calcium-dependent human homologue of leguminous lectins.	Mannose	25-32	lectin, mannose binding 1	Homo sapiens	0-8
8845173-8	1996	PC attachment by SP-A was calcium- and mannose-dependent as SP-A-mediated attachment was significantly reduced in the presence of EGTA and mannose to 13.1 +/- 1.6% and 19.3 +/- 2.6%, respectively (P&lt;0.05).	Mannose	39-46	surfactant protein A1	Homo sapiens	17-21
8845173-8	1996	PC attachment by SP-A was calcium- and mannose-dependent as SP-A-mediated attachment was significantly reduced in the presence of EGTA and mannose to 13.1 +/- 1.6% and 19.3 +/- 2.6%, respectively (P&lt;0.05).	Mannose	39-46	surfactant protein A1	Homo sapiens	60-64
8845173-8	1996	PC attachment by SP-A was calcium- and mannose-dependent as SP-A-mediated attachment was significantly reduced in the presence of EGTA and mannose to 13.1 +/- 1.6% and 19.3 +/- 2.6%, respectively (P&lt;0.05).	Mannose	139-146	surfactant protein A1	Homo sapiens	17-21
8845173-8	1996	PC attachment by SP-A was calcium- and mannose-dependent as SP-A-mediated attachment was significantly reduced in the presence of EGTA and mannose to 13.1 +/- 1.6% and 19.3 +/- 2.6%, respectively (P&lt;0.05).	Mannose	139-146	surfactant protein A1	Homo sapiens	60-64
8617714-1	1996	The serum-mannan binding protein (S-MBP) is a calcium-dependent C-type lectin specific for mannose and N-acetylglucosamine.	Mannose	91-98	mannose-binding lectin (protein A) 1	Mus musculus	4-32
8617714-1	1996	The serum-mannan binding protein (S-MBP) is a calcium-dependent C-type lectin specific for mannose and N-acetylglucosamine.	Mannose	91-98	mannose-binding lectin (protein A) 1	Mus musculus	34-39
8617714-7	1996	Deglycosylation experiments with N-glycanase and endoglycosidase H indicated that the S-MBP ligands on thymic CD45 are high mannose type or hybrid type N-linked oligosaccharides.	Mannose	124-131	mannose-binding lectin (protein A) 1	Mus musculus	86-91
8617714-7	1996	Deglycosylation experiments with N-glycanase and endoglycosidase H indicated that the S-MBP ligands on thymic CD45 are high mannose type or hybrid type N-linked oligosaccharides.	Mannose	124-131	protein tyrosine phosphatase, receptor type, C	Mus musculus	110-114
8868475-6	1996	Overexpressed ERGIC-53 binds to a mannose column in a calcium-dependent manner and also co-stains with mannosylated neoglycoprotein in a morphological binding assay.	Mannose	34-41	lectin, mannose binding 1	Homo sapiens	14-22
8868475-7	1996	By using a sequential elution protocol we show that ERGIC-53 has selectivity for mannose and low affinity for glucose and GlcNAc, but no affinity for galactose.	Mannose	81-88	lectin, mannose binding 1	Homo sapiens	52-60
8825806-0	1996	Turnover and distribution of intravenously administered mannose-terminated human acid beta-glucosidase in murine and human tissues.	Mannose	56-63	glucosylceramidase beta	Homo sapiens	81-102
8626751-7	1996	Both unglycosylated human granzyme B (26 kDa) and that bearing high mannose glycosylation (32 kDa) were internalized and bound within nuclei, but forms greater than 32 kDa with complex carbohydrate addition were excluded.	Mannose	68-75	granzyme B	Homo sapiens	26-36
8626776-11	1996	These results indicate that P-selectin binds sLeX in a shallow cleft that is similar to the mannose-binding protein saccharide-binding cleft.	Mannose	92-99	selectin P	Rattus norvegicus	28-38
8626776-14	1996	Functionally, it appears that P-selectin has retained a conserved carbohydrate and calcium coordination site that enables it to bind carbohydrate in a manner that is quite similar to that which has been determined for the rat mannose-binding protein.	Mannose	226-233	selectin P	Rattus norvegicus	30-40
8609217-3	1996	Here, we analyze at the molecular level a phenotype of congenital sucrase-isomaltase deficiency in which sucrase-isomaltase (SI) is not transported to the brush border membrane but accumulates as a mannose-rich precursor in the endoplasmic reticulum (ER), ER-Golgi intermediate compartment, and the cis-Golgi, where it is finally degraded.	Mannose	198-205	sucrase-isomaltase	Homo sapiens	66-84
8557671-5	1996	Surprisingly, the pyranose ring of mannose is rotated 180 degrees relative to the orientation observed previously in MBP-A, but the local interactions between sugar and protein are preserved.	Mannose	35-42	mannose binding lectin 1	Rattus norvegicus	117-122
12226203-3	1996	The enzyme was endo-[beta]-mannanase (EC 3.2.1.78), since it hydrolyzed galactomannan into oligosaccharides with no release of galactose and mannose.	Mannose	141-148	LOW QUALITY PROTEIN: mannan endo-1,4-beta-mannosidase 3	Solanum lycopersicum	15-36
8557671-4	1996	Complexes of MBP-C with methyl glycosides of mannose, N-acetylglucosamine, and fucose were prepared by soaking MBP-C crystals in solutions containing these sugars.	Mannose	45-52	mannose binding lectin 2	Rattus norvegicus	13-18
8745411-6	1996	Mammalian cell derived IFN-gamma molecules displayed oligosaccharides with monosaccharide compositions equivalent to complex, sialylated, or high-mannose type N-glycans.	Mannose	146-153	interferon gamma	Homo sapiens	23-32
8557671-9	1996	A second binding site for mannose has also been observed in one of two copies in the asymmetric unit at a sugar concentration of 1.3 M. These structures explain how MBPs recognize a wide range of monosaccharides and suggest how fine specificity differences between MBP-A and MBP-C may be achieved.	Mannose	26-33	myelin basic protein	Rattus norvegicus	165-169
8557671-9	1996	A second binding site for mannose has also been observed in one of two copies in the asymmetric unit at a sugar concentration of 1.3 M. These structures explain how MBPs recognize a wide range of monosaccharides and suggest how fine specificity differences between MBP-A and MBP-C may be achieved.	Mannose	26-33	mannose binding lectin 1	Rattus norvegicus	265-270
8557671-9	1996	A second binding site for mannose has also been observed in one of two copies in the asymmetric unit at a sugar concentration of 1.3 M. These structures explain how MBPs recognize a wide range of monosaccharides and suggest how fine specificity differences between MBP-A and MBP-C may be achieved.	Mannose	26-33	mannose binding lectin 2	Rattus norvegicus	275-280
7492596-7	1995	In particular, a reduced multiantennary complex type sugar chain and an elevated high-mannose or hybrid-type sugar chain in the microsomal fraction were observed in the GGT in cancerous tissues.	Mannose	86-93	gamma-glutamyltransferase 1	Homo sapiens	169-172
8907186-5	1996	The monomeric protein was generated primarily as the 46-kDa pro-CE with a high-mannose-type oligosaccharide chain in the cells.	Mannose	79-86	cathepsin E	Homo sapiens	64-66
8838507-5	1996	Purified human serum lectin MBP was used to quantify the degree of exposed mannose or N-acetylglucosamine residues in the Fc region of anti-LTSRPA IgG of patients with RA and healthy controls.	Mannose	75-82	myelin basic protein	Homo sapiens	28-31
8838507-9	1996	As MBP binding depends on exposed mannose or N-acetylglucosamine residues in the Fc region of the IgG molecule, these studies suggest that defective glycosylation of circulating anti-SK IgG may play a role in the etiology of RA.	Mannose	34-41	myelin basic protein	Homo sapiens	3-6
8950359-8	1996	In contrast, only high mannose-type N-linked glycans are present on the PSMA from LNCaP cells.	Mannose	23-30	folate hydrolase 1	Homo sapiens	72-76
8748159-1	1995	N-Acetylglucosaminyltransferase V (GlcNAc-T V) is a glycosyltransferase which transfers N-acetylglucosamine in beta(1,6) linkage to the alpha(1,6)-linked mannose residue of Asn-linked oligosaccharides.	Mannose	154-161	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	0-33
8748159-1	1995	N-Acetylglucosaminyltransferase V (GlcNAc-T V) is a glycosyltransferase which transfers N-acetylglucosamine in beta(1,6) linkage to the alpha(1,6)-linked mannose residue of Asn-linked oligosaccharides.	Mannose	154-161	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	35-45
8542195-1	1995	It has been proposed that in mammalian systems the glucose analog 2-fluoro-2-deoxy-D-glucose (FDG) is phosphorylated and subsequently converted to the corresponding mannose derivative via the action of phosphoglucose isomerase.	Mannose	165-172	glucose-6-phosphate isomerase	Homo sapiens	202-226
9116059-2	1996	This mannose-rich 34-kDa protein specifically bound human growth hormone (hGH) with the same affinity (kDa = 0.42 x 10(-9) M) than the 51.5 kDa GHBP we purified and characterised from human plasma (kDa = 1.1 x 10(-9) M).	Mannose	5-12	growth hormone 1	Homo sapiens	58-72
8680122-8	1996	Furthermore, we also detected gastrin receptors in the esophageal lesions produced by the oral administration of MAN to rats.	Mannose	113-116	gastrin	Homo sapiens	30-37
8520747-1	1995	Pulmonary surfactant protein D (SP-D) is a hydrophilic glycoprotein with a reduced molecular mass of 43 kDa and a member of the C-type lectin superfamily, along with mannose-binding proteins and surfactant protein A (SP-A).	Mannose	166-173	surfactant protein D	Homo sapiens	32-36
7503563-3	1995	Binding and uptake of bee venom PLA2 by J774E macrophages was shown to be competed by mannose-BSA, glucose-BSA, N-acetylglucosamine-BSA, but not by galactose-BSA, indicating that the binding of bee venom PLA2 is probably mediated by macrophage mannose receptor.	Mannose	86-93	phospholipase A2 group IIA	Homo sapiens	32-36
8787777-7	1995	TAP is composed of mannose, xylose, glucuronic acid and glucose (molar ratio, 4:2:1:0.3), and it contains 2.2% of O-acetyl groups.	Mannose	19-26	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	Mus musculus	0-3
7487100-4	1995	We detected high mannose dimers of the lactase-phlorizin hydrolase precursor molecule after metabolic labeling with [35S]methionine at 37 and 15 degrees C. In addition, both complex-glycosylated lactase-phlorizin hydrolase precursor molecule and the mature microvillus membrane-bound enzyme showed this oligomeric structure.	Mannose	17-24	lactase	Homo sapiens	39-66
7487100-4	1995	We detected high mannose dimers of the lactase-phlorizin hydrolase precursor molecule after metabolic labeling with [35S]methionine at 37 and 15 degrees C. In addition, both complex-glycosylated lactase-phlorizin hydrolase precursor molecule and the mature microvillus membrane-bound enzyme showed this oligomeric structure.	Mannose	17-24	lactase	Homo sapiens	195-222
8847092-1	1995	Specific cytotoxicity of human CD56+NK and LAK cells was quantitatively inhibited by acetylated mannose, galactose and glucose (Scand.	Mannose	96-103	neural cell adhesion molecule 1	Homo sapiens	31-38
8847092-1	1995	Specific cytotoxicity of human CD56+NK and LAK cells was quantitatively inhibited by acetylated mannose, galactose and glucose (Scand.	Mannose	96-103	alpha kinase 1	Homo sapiens	43-46
8656071-11	1995	SDS-PAGE/fluorography demonstrated that wild-type LCAT was synthesized as a high-mannose type of 56 kDa, which was very slowly converted to a mature form of 67 kDa and was secreted into the media.	Mannose	81-88	lecithin-cholesterol acyltransferase	Homo sapiens	50-54
7595054-8	1995	The same saccharides that disrupt CD87/CR3 coupling (NADG, D-mannose, and mannoside) inhibit PMN chemotaxis.	Mannose	59-68	plasminogen activator, urokinase receptor	Homo sapiens	34-38
7595054-8	1995	The same saccharides that disrupt CD87/CR3 coupling (NADG, D-mannose, and mannoside) inhibit PMN chemotaxis.	Mannose	59-68	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	39-42
8608269-2	1995	Structural studies on oligosaccharides from alg3 mutant yeast, which lack the four upper arm mannoses donated by Man-P-Dol (where Dol is dolichol), verified that the new alpha 1,6-branch in endo H-resistant mannan in this strain is efficiently initiated in vivo on the alpha 1,3-linked core residue of the lipid-oligosaccharide form of Man5GlcNAc2 (Verostek et al., J. Biol.	Mannose	93-101	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	44-48
7557068-6	1995	The transient high mannose-glycosylated form of fetal aminopeptidase N was processed to the mature complex-glycosylated form at a markedly slower rate than the enzyme in adult intestine.	Mannose	19-26	alanyl aminopeptidase, membrane	Sus scrofa	54-70
7576538-4	1995	Unlike plasma alpha 1AT, however, treatment of the yeast-produced alpha 1AT with endoglycosidase H decreased the molecular mass to that of recombinant alpha 1AT produced in Escherichia coli, indicating the high-mannose type N-linked glycosylation of the secreted alpha 1AT.	Mannose	211-218	serpin family A member 1	Homo sapiens	66-75
7576538-4	1995	Unlike plasma alpha 1AT, however, treatment of the yeast-produced alpha 1AT with endoglycosidase H decreased the molecular mass to that of recombinant alpha 1AT produced in Escherichia coli, indicating the high-mannose type N-linked glycosylation of the secreted alpha 1AT.	Mannose	211-218	serpin family A member 1	Homo sapiens	66-75
7576538-4	1995	Unlike plasma alpha 1AT, however, treatment of the yeast-produced alpha 1AT with endoglycosidase H decreased the molecular mass to that of recombinant alpha 1AT produced in Escherichia coli, indicating the high-mannose type N-linked glycosylation of the secreted alpha 1AT.	Mannose	211-218	serpin family A member 1	Homo sapiens	66-75
7474508-8	1995	The binding of IgA1 to THP-1 was partially, but definitely inhibited by adding 100 mM melibiose (19.6 +/- 7.7%) and galactose (13.1 +/- 2.9%), but not glucose (2.9 +/- 2.2%), lactose (4.7 +/- 4.7%) and mannose (3.3 +/- 3.3%).	Mannose	202-209	immunoglobulin heavy constant alpha 1	Homo sapiens	15-19
7474508-8	1995	The binding of IgA1 to THP-1 was partially, but definitely inhibited by adding 100 mM melibiose (19.6 +/- 7.7%) and galactose (13.1 +/- 2.9%), but not glucose (2.9 +/- 2.2%), lactose (4.7 +/- 4.7%) and mannose (3.3 +/- 3.3%).	Mannose	202-209	GLI family zinc finger 2	Homo sapiens	23-28
7590884-8	1995	These findings demonstrate that alpha 2-macroglobulin is the essential serum factor in liposome-primed macrophage activation, and that modified alpha 2-macroglobulin with mannose residues at the terminal sugar chain binds to macrophage mannose receptors, but not alpha 2-macroglobulin receptors, and increases Fc gamma receptor-mediated phagocytosis of IgG-opsonized sheep red blood cells.	Mannose	171-178	alpha-2-macroglobulin	Ovis aries	144-165
8563142-14	1995	Binding of the chicken MBP to mannan was inhibited by monosaccharides in the following order of potency: ManNAc &gt; L-fucose &gt; mannose &gt; N-acetylglucosamine.	Mannose	131-138	myelin basic protein	Gallus gallus	23-26
7590884-8	1995	These findings demonstrate that alpha 2-macroglobulin is the essential serum factor in liposome-primed macrophage activation, and that modified alpha 2-macroglobulin with mannose residues at the terminal sugar chain binds to macrophage mannose receptors, but not alpha 2-macroglobulin receptors, and increases Fc gamma receptor-mediated phagocytosis of IgG-opsonized sheep red blood cells.	Mannose	171-178	alpha-2-macroglobulin	Ovis aries	144-165
7570874-0	1995	Leishmania donovani: titration of antibodies to the fucose-mannose ligand as an aid in diagnosis and prognosis of visceral leishmaniasis.	Mannose	59-66	activation induced cytidine deaminase	Homo sapiens	80-83
7474402-2	1995	Study of the oligosaccharide structures of gp120 suggests that the high mannose type of oligosaccharides are essential for HIV-1 infection.	Mannose	72-79	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	43-48
7474402-4	1995	The inhibitory effect was suppressed by addition of high mannose type oligosaccharides of gp120.	Mannose	57-64	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	90-95
7544912-7	1995	Fractionation of pMBP-containing D-mannose eluate from mannan-Sepharose on Superose 6 showed two protein peaks which reacted with anti-C1 s antibodies in ELISA, one of about 650-800 kDa, which in addition contained pMBP-28 and anti-alpha 2M reactive material, the other with an M(r) of 100-150 kDa.	Mannose	33-42	progesterone receptor membrane component 2	Homo sapiens	17-21
7622208-8	1995	Mannose-resistant hemagglutination of human erythrocytes observed in the presence of EAggEC strains was inhibited in the presence of anti-OMP serum.	Mannose	0-7	olfactory marker protein	Homo sapiens	138-141
8528944-0	1995	Glycosylated human recombinant interleukin-1 alpha, neo interleukin-1 alpha, with D-mannose dimer exhibits selective activities in vivo.	Mannose	84-91	interleukin 1 alpha	Homo sapiens	31-50
8528944-0	1995	Glycosylated human recombinant interleukin-1 alpha, neo interleukin-1 alpha, with D-mannose dimer exhibits selective activities in vivo.	Mannose	84-91	interleukin 1 alpha	Homo sapiens	56-75
7629073-9	1995	When expressed in COS7 cells as a secreted protein A fusion protein, the catalytic domain of clone 16 displays alpha-1,2-mannosidase activity using [3H]mannose-labeled Man9GlcNAc as substrate, but the corresponding region of clone 4 is poorly secreted under identical conditions.	Mannose	152-159	testis-specific serine kinase substrate	Mus musculus	225-232
7618283-8	1995	In the presence of DMJ, a mannosidase I inhibitor, MCP is synthesized with N-glycans of the high-mannose type in contrast to the complex oligosaccharides present on MCP of untreated cells.	Mannose	97-104	CD46 molecule	Homo sapiens	51-54
7618283-9	1995	Both MCP with mannose-rich and MCP with complex N-glycans were recognized by measles virus H protein in an in vitro binding assay.	Mannose	14-21	CD46 molecule	Homo sapiens	5-8
7797531-6	1995	Brain alpha-dystroglycan expresses high mannose/hybrid N-linked saccharides, terminal GalNAc residues, and the HNK-1 epitope.	Mannose	40-47	dystroglycan 1	Rattus norvegicus	6-24
7797505-1	1995	UDP-N-acetyl-D-glucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II (EC 2.4.1.143) (GnT II) is a Golgi resident enzyme that catalyzes an essential step in the biosynthetic pathway leading from high mannose to complex N-linked oligosaccharides.	Mannose	221-228	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	47-90
7592547-1	1995	In the previous study involving a yeast expression system, a high molecular mass extracellular domain of human tissue factor (denoted as sTF alpha) with a high content of mannose residues was produced in abundance and 37 kDa sTF beta was obtained in a low yield [Shigematsu et al.	Mannose	171-178	coagulation factor III, tissue factor	Homo sapiens	111-124
7797505-1	1995	UDP-N-acetyl-D-glucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II (EC 2.4.1.143) (GnT II) is a Golgi resident enzyme that catalyzes an essential step in the biosynthetic pathway leading from high mannose to complex N-linked oligosaccharides.	Mannose	221-228	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	107-113
7742312-2	1995	Measurements of kcat/Km showed that glucokinase phosphorylated the sugars in the order glucose = mannose &gt; deoxyglucose &gt; fructose = glucosamine.	Mannose	97-104	glucokinase	Homo sapiens	36-47
7742312-11	1995	The calculated interaction energies of glucokinase with glucose, mannose, deoxyglucose, and fructose agree very well with the measured values of kcat/Km, which indicates that these sugars are recognized by binding to the open conformation of glucokinase.	Mannose	65-72	glucokinase	Homo sapiens	39-50
7742312-11	1995	The calculated interaction energies of glucokinase with glucose, mannose, deoxyglucose, and fructose agree very well with the measured values of kcat/Km, which indicates that these sugars are recognized by binding to the open conformation of glucokinase.	Mannose	65-72	glucokinase	Homo sapiens	242-253
7787299-6	1995	Approximately 7.2% of carbohydrate from PAS-4 was composed of mannose, galactose (Gal), N-acetylglucosamine, N-acetylgalactosamine (GalNAc), and sialic acid, most of the Gal and GalNAc in PAS-4 being released after mild alkaline hydrolysis.	Mannose	62-69	PAS-4	Bos taurus	40-45
7727533-4	1995	Because cell walls of cwh6 are greatly reduced in mannose, and because some cell wall proteins are known to be incorporated into the cell wall through a GPI-anchor dependent mechanism, we propose that Spt14p/Cwh6p is involved in transferring N-acetylglucosamine to a precursor of GPI anchors.	Mannose	50-57	phosphatidylinositol N-acetylglucosaminyltransferase SPT14	Saccharomyces cerevisiae S288C	22-26
7727533-4	1995	Because cell walls of cwh6 are greatly reduced in mannose, and because some cell wall proteins are known to be incorporated into the cell wall through a GPI-anchor dependent mechanism, we propose that Spt14p/Cwh6p is involved in transferring N-acetylglucosamine to a precursor of GPI anchors.	Mannose	50-57	phosphatidylinositol N-acetylglucosaminyltransferase SPT14	Saccharomyces cerevisiae S288C	201-207
7727533-4	1995	Because cell walls of cwh6 are greatly reduced in mannose, and because some cell wall proteins are known to be incorporated into the cell wall through a GPI-anchor dependent mechanism, we propose that Spt14p/Cwh6p is involved in transferring N-acetylglucosamine to a precursor of GPI anchors.	Mannose	50-57	phosphatidylinositol N-acetylglucosaminyltransferase SPT14	Saccharomyces cerevisiae S288C	208-213
7729572-4	1995	Sensory afferent defasciculation and arborization in the neuropil were inhibited by culturing embryos in Fab fragments directed against the mannose-containing surface epitope of sensory afferents.	Mannose	140-147	FA complementation group B	Homo sapiens	105-108
7592547-6	1995	We found that the yield of the beta form of the Asn137-to-Ala mutant (designated as sTF beta NNA) was threefold higher (3 mg/liter) than that of the wild type, suggesting that the replacement of one of the three potential N-glycosylation Asn residues with Ala could be a good way to minimize the addition of mannose repeats.	Mannose	308-315	cystatin B	Homo sapiens	84-92
7782337-5	1995	The indicated mutations have previously been shown to change the carbohydrate binding specificity of surfactant protein A and mannose-binding protein from mannose &gt; galactose to the converse.	Mannose	126-133	surfactant protein A1	Homo sapiens	101-121
7782337-5	1995	The indicated mutations have previously been shown to change the carbohydrate binding specificity of surfactant protein A and mannose-binding protein from mannose &gt; galactose to the converse.	Mannose	155-162	surfactant protein A1	Homo sapiens	101-121
7539797-8	1995	Analysis of this model indicated that the alteration of one E-selectin amino acid, alanine 77, to a lysine residue might shift binding specificity from sLe(x) to mannose.	Mannose	162-169	selectin E	Homo sapiens	60-70
7539797-9	1995	The results presented here show that an E-selectin mutant protein possessing this change displays preferential binding to mannose containing oligosaccharides and that further mutagenesis of this mannose-binding selectin confers galactose recognition in a predictable manner.	Mannose	122-129	selectin E	Homo sapiens	40-50
7539797-9	1995	The results presented here show that an E-selectin mutant protein possessing this change displays preferential binding to mannose containing oligosaccharides and that further mutagenesis of this mannose-binding selectin confers galactose recognition in a predictable manner.	Mannose	195-202	selectin E	Homo sapiens	40-50
7707811-2	1995	A mutation in mannose binding protein (MBP) caused by point mutations in the MBP gene will lead to such a defect.	Mannose	14-21	myelin basic protein	Homo sapiens	39-42
7707811-2	1995	A mutation in mannose binding protein (MBP) caused by point mutations in the MBP gene will lead to such a defect.	Mannose	14-21	myelin basic protein	Homo sapiens	77-80
8529110-2	1995	Alglucerase is a form of glucocerebrosidase enriched with terminal mannose moieties, so as to "target" the preparation to the high-affinity macrophage receptor in patients with Gaucher disease.	Mannose	67-74	glucosylceramidase beta	Homo sapiens	0-11
7536792-4	1995	The binding of modified alpha 2-macroglobulin to macrophages was also reduced by the addition of D-mannose.	Mannose	97-106	alpha-2-macroglobulin	Mus musculus	24-45
7774024-0	1995	Disaccharides as endomannosidase inhibitors: syntheses of alpha-homomannojirimycin and beta-homomannojirimycin linked to D-glucose and D-mannose.	Mannose	135-144	mannosidase endo-alpha	Homo sapiens	17-32
7873598-6	1995	These activities were inhibited by D-mannose, N-acetyl-D-galactosamine, and D-maltose which are haptenic saccharides of authentic hemocytin.	Mannose	35-44	hemocytin	Bombyx mori	130-139
7540906-3	1995	The structure of this domain from rat mannose-binding protein (MBP-A) has been solved by X-ray crystallography (Weis WI, Drickamer K, Hendrickson WA, 1992, Nature 360:127-134) and provided the coordinates for constructing the three-dimensional model of the 129-amino acid Type II AFP from sea raven, to which it shows 19% sequence identity.	Mannose	38-45	mannose binding lectin 1	Rattus norvegicus	63-68
7876089-0	1995	ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells.	Mannose	129-136	lectin, mannose binding 1	Homo sapiens	0-8
7876089-0	1995	ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells.	Mannose	129-136	lectin, mannose binding 1	Homo sapiens	106-110
7876089-1	1995	A mannose-specific membrane lectin (MR60) isolated from human myelomonocytic HL60 cells by affinity chromatography is expressed in intracellular organelles of immature monocytes (Pimpaneau, V., Midoux, P., Monsigny, M., and Roche, A. C. (1991) Carbohydr.	Mannose	2-9	lectin, mannose binding 1	Homo sapiens	36-40
7770063-4	1995	In contrast, two mannose-specific lectins, the mannan-binding protein (MBP) and serum amyloid P component (SAP), isolated from human serum, have inhibitory effects, both in the absence and presence of EGF.	Mannose	17-24	myelin basic protein	Homo sapiens	47-69
7759558-0	1995	Studies on the turnover of exogenous mannose-terminal glucocerebrosidase in rat liver lysosomes.	Mannose	37-44	glucosylceramidase beta	Rattus norvegicus	54-72
7759558-9	1995	Immunoelectron microscopy of rat liver following infusion of mannose-terminal glucocerebrosidase confirmed localization of the delivered enzyme primarily within the lumen of the lysosomes of Kupffer cells and to a lesser extent associated with the lysosomal membrane.	Mannose	61-68	glucosylceramidase beta	Rattus norvegicus	78-96
7759558-10	1995	Enzyme activity was stable in isolated rat liver lysosomes preloaded with mannose-terminal glucocerebrosidase and incubated in the absence or presence of ATP.	Mannose	74-81	glucosylceramidase beta	Rattus norvegicus	91-109
7822772-2	1995	Selective uptake of mannose-terminal glucocerebrosidase by Kupffer cells in rat liver has been previously demonstrated biochemically.	Mannose	20-27	glucosylceramidase beta	Rattus norvegicus	37-55
7822772-14	1995	We conclude that mannose-terminal glucocerebrosidase is delivered to the lysosomes of Kupffer cells in liver and that it is distributed both within the lumen (82%) and over the membrane (18%) of the lysosome, with a slight preferential association with the membrane.	Mannose	17-24	glucosylceramidase beta	Rattus norvegicus	34-52
7849022-3	1995	This adhesion domain in human CD2 contains a single high-mannose N-glycan.	Mannose	57-64	CD2 molecule	Homo sapiens	30-33
7774749-3	1995	Combining prostasomes with 5 mmol/l of any of the hexoses fructose, glucose or mannose (but not galactose) resulted in a prolongation and improvement of the effect by prostasomes (or albumin) for the first 150 min.	Mannose	79-86	albumin	Homo sapiens	183-190
7852489-8	1995	The fraction firmly bound to Con-canavalin-A, which contains hCG with high mannose and hybrid-type carbohydrate chains, was significantly higher in the hyperemesis group (91.07 +/- 2.06%; n = 15) than in the no emesis group (89.61 +/- 2.38%; n = 24; P &lt; 0.04).	Mannose	75-82	chorionic gonadotropin subunit beta 5	Homo sapiens	61-64
7770063-4	1995	In contrast, two mannose-specific lectins, the mannan-binding protein (MBP) and serum amyloid P component (SAP), isolated from human serum, have inhibitory effects, both in the absence and presence of EGF.	Mannose	17-24	myelin basic protein	Homo sapiens	71-74
7770063-4	1995	In contrast, two mannose-specific lectins, the mannan-binding protein (MBP) and serum amyloid P component (SAP), isolated from human serum, have inhibitory effects, both in the absence and presence of EGF.	Mannose	17-24	amyloid P component, serum	Homo sapiens	80-105
7770063-4	1995	In contrast, two mannose-specific lectins, the mannan-binding protein (MBP) and serum amyloid P component (SAP), isolated from human serum, have inhibitory effects, both in the absence and presence of EGF.	Mannose	17-24	amyloid P component, serum	Homo sapiens	107-110
7985893-1	1995	OBJECTIVE: To compare the efficacy of mannose-terminated glucocerbrosidase prepared from natural (alglucerase; Ceredase, Genzyme Corp., Cambridge, Massachusetts) and recombinant (imiglucerase; Cerezyme, Genzyme Corp.) sources in treating type 1 Gaucher disease.	Mannose	38-45	glucosylceramidase beta	Homo sapiens	179-191
7653160-2	1995	Glycan chain analysis performed with the use of a Glycan Differentiation Kit showed that basic forms of arylsulfatase B from human placenta contained mostly high mannose/hybrid type glycans, with 6-O-L-fucose bound to the innermost N-acetylglucosamine residue, whereas acidic forms of the enzyme contained complex type glycans containing fucose and sialic acid.	Mannose	162-169	arylsulfatase B	Homo sapiens	104-119
8597490-7	1995	Three different forms of the LH receptor are physiologically expressed: a mature 85kDa transmembrane species, a 68 kDa high mannose containing species corresponding to a precursor which accumulates inside the cells, and truncated 45-48kDa molecular weight species corresponding to the variant messenger RNAs identified during the cloning of the receptor.	Mannose	124-131	luteinizing hormone/choriogonadotropin receptor	Homo sapiens	29-40
7890120-11	1994	The study shows that both subunits of arylsulfatase A from human placenta possess two high mannose/hybrid type glycans as major structures, with at least one 6-O-L-fucose bound to the innermost N-acetylglucosamine on each.	Mannose	91-98	arylsulfatase A	Homo sapiens	38-53
7768754-1	1995	A D-mannosylated albumin (DMA) neoglycoprotein was assessed to validate experimentally a probe capable of detecting mannose-binding sperm receptors involved in human sperm-egg interaction.	Mannose	116-123	major histocompatibility complex, class II, DM alpha	Homo sapiens	2-24
7768754-1	1995	A D-mannosylated albumin (DMA) neoglycoprotein was assessed to validate experimentally a probe capable of detecting mannose-binding sperm receptors involved in human sperm-egg interaction.	Mannose	116-123	major histocompatibility complex, class II, DM alpha	Homo sapiens	26-29
7768754-12	1995	In conclusion, DMA is a suitable probe to identify human sperm mannose-binding sites crucially involved in sperm-zona interaction.	Mannose	63-70	major histocompatibility complex, class II, DM alpha	Homo sapiens	15-18
7798246-3	1994	Using comparative computer modeling and inverse folding calculations, we have generated and analyzed a detailed three-dimensional model of the extracellular domain of CD69 based on the crystal structure of the mannose binding protein.	Mannose	210-217	CD69 molecule	Homo sapiens	167-171
7798246-5	1994	Compared with mannose binding protein and the selectins, CD69 displays significant deletions in loop regions.	Mannose	14-21	CD69 molecule	Homo sapiens	57-61
7994038-9	1994	However, PBMC treated with D-mannose before fixation resulted in a loss of activity; this loss of activity was associated with release of IL-1 alpha, not IL-1 beta, into the supernatant.	Mannose	27-36	interleukin 1 alpha	Homo sapiens	138-148
7982953-6	1994	Moreover, the substitution of either alpha 1-3 or alpha 1-6 linked mannosyl residues of M5Gn or both by mannose in alpha 1-2 linkage leads to a considerable reduction of their inhibitory power.	Mannose	104-111	adrenoceptor alpha 1D	Homo sapiens	37-59
7982953-6	1994	Moreover, the substitution of either alpha 1-3 or alpha 1-6 linked mannosyl residues of M5Gn or both by mannose in alpha 1-2 linkage leads to a considerable reduction of their inhibitory power.	Mannose	104-111	adrenoceptor alpha 1D	Homo sapiens	37-44
7734844-3	1994	This conformation is stabilized by the formation of a hydrogen bond between the carbonyl oxygen of GlcNAc2 with the O3/O4 hydroxyls of the alpha 1,6-linked mannose residue.	Mannose	156-163	adrenoceptor alpha 1D	Homo sapiens	139-148
7962050-8	1994	Carbohydrate analysis of the invertase-Wbp1 fusion protein using mannose linkage-specific antiserum demonstrated that the fusion protein was efficiently modified by the early Golgi initial alpha 1,6 mannosyltransferase (Och1p).	Mannose	65-72	dolichyl-diphosphooligosaccharide-protein glycotransferase	Saccharomyces cerevisiae S288C	39-43
9492758-4	1994	A key enzymatic step required for branching to occur would be the transfer of a residue of N-acetylglucosamine to the terminal unsubstituted mannose residue of the major rhodopsin oligosaccharide.	Mannose	141-148	rhodopsin	Homo sapiens	170-179
7894166-0	1994	The murine mannose-binding protein genes (Mbl 1 and Mbl 2) localize to chromosomes 14 and 19.	Mannose	11-18	mannose-binding lectin (protein A) 1	Mus musculus	42-47
7894166-0	1994	The murine mannose-binding protein genes (Mbl 1 and Mbl 2) localize to chromosomes 14 and 19.	Mannose	11-18	mannose-binding lectin (protein C) 2	Mus musculus	52-57
7962051-5	1994	Self-modification of Mnn1p with alpha 1,3 mannose epitopes, primarily on O-linked oligosaccharides, is at least partly responsible for the incremental increase in molecular mass.	Mannose	42-49	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	21-26
7813575-4	1994	The mannose glycosylation site on the kringle 1 of tissue-type plasminogen activator is modified to yield a compound with a longer half-life in the blood than native tissue-type plasminogen activator.	Mannose	4-11	plasminogen activator, tissue type	Rattus norvegicus	51-84
7535137-3	1994	In this study, we report the new findings of the mannan-binding property of L-929 PNGase: the de-N-glycosylating enzyme activity of L-929 PNGase was inhibited by yeast mannan and triomannose, Man alpha 1--&gt;3(Man alpha 1--&gt;6)Man, but not by mannose and alpha-methyl-D-mannoside.	Mannose	183-190	N-glycanase 1	Homo sapiens	82-88
7535137-3	1994	In this study, we report the new findings of the mannan-binding property of L-929 PNGase: the de-N-glycosylating enzyme activity of L-929 PNGase was inhibited by yeast mannan and triomannose, Man alpha 1--&gt;3(Man alpha 1--&gt;6)Man, but not by mannose and alpha-methyl-D-mannoside.	Mannose	183-190	N-glycanase 1	Homo sapiens	138-144
7919388-4	1994	We report the presence of a 65-kD precursor of gp91-phox in the membrane fraction of both p22-phox-deficient cell lines, corresponding to the core protein with N-linked carbohydrate side chains in the high mannose form.	Mannose	206-213	cytochrome b-245 beta chain	Homo sapiens	47-56
7813575-4	1994	The mannose glycosylation site on the kringle 1 of tissue-type plasminogen activator is modified to yield a compound with a longer half-life in the blood than native tissue-type plasminogen activator.	Mannose	4-11	plasminogen activator, tissue type	Rattus norvegicus	166-199
7537165-5	1994	Pretreatment of the Caco-2 cells with the beta 1 integrin receptor competitive inhibitors fibronectin or RGD did not inhibit BT; while pretreatment of Caco-2 cells with the LFA-1 (lectin) receptor competitive inhibitor mannose (12 mg/ml) or purified mucin (8 mg/ml) decreased BT compared to control membranes (p &lt; .001).	Mannose	219-226	integrin subunit beta 2	Homo sapiens	173-196
8051137-10	1994	The sugar specificity of STP1 was D-mannose &gt; or = 2-deoxyglucose &gt; D-galactose &gt; or = 3OMG &gt; D-xylose &gt; D-glucose &gt; D-fucose &gt; D-fructose &gt; L-glucose &gt; L-arabinose &gt; D-arabinose, demonstrating that STP1 has a low substrate specificity.	Mannose	34-43	sugar transporter 1	Arabidopsis thaliana	25-29
7873926-1	1994	Serum mannan-binding protein (S-MBP), a lectin specific for mannose and N-acetylglucosamine, activates complement through the classical pathway.	Mannose	60-67	transmembrane 9 superfamily member 3	Homo sapiens	30-35
7873926-5	1994	S-MBP bound to the dMM-treated BHK cells in the presence of Ca2+, and this binding was eliminated by mannose.	Mannose	101-108	transmembrane 9 superfamily member 3	Homo sapiens	0-5
7873929-1	1994	Myelomonocytic lineage cells express an M(r) 60,000 mannose specific lectin, MR60 (Pimpaneau et al.	Mannose	52-59	lectin, mannose binding 1	Homo sapiens	77-81
7829133-0	1994	Identification of a mannose-acetate-specific 87-kDa receptor responsible for human NK and LAK activity.	Mannose	20-27	ADP ribosylation factor like GTPase 4C	Homo sapiens	90-93
7829133-1	1994	Target cell recognition and cytotoxicity of human CD56+ NK and LAK cells is readily inhibited by acetylated mannose.	Mannose	108-115	neural cell adhesion molecule 1	Homo sapiens	50-54
7829133-1	1994	Target cell recognition and cytotoxicity of human CD56+ NK and LAK cells is readily inhibited by acetylated mannose.	Mannose	108-115	ADP ribosylation factor like GTPase 4C	Homo sapiens	63-66
7826422-8	1994	Comparison of the sugar moieties of the glycoproteins used as inhibitors led to suggestion that the specific sugar binding site contains, as a dominant sugar, a "bisecting" glucosamine attached through a beta-1,4-linkage to the beta-linked mannose residue of N-glycosidic chains of a complex or hybrid type.	Mannose	240-247	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	204-210
7827406-5	1994	The enzyme is an alpha 1,2-mannosidase that trims Man9GlcNAc to Man5 GlcNAc (where Man is mannose and GlcNAc is N-acetyl glucosamine).	Mannose	90-97	mannosidase alpha class 1A member 2	Homo sapiens	17-38
7827406-5	1994	The enzyme is an alpha 1,2-mannosidase that trims Man9GlcNAc to Man5 GlcNAc (where Man is mannose and GlcNAc is N-acetyl glucosamine).	Mannose	90-97	mannosidase alpha class 1A member 1	Homo sapiens	50-54
7999926-0	1994	Development of glycosylated human interleukin-1 alpha, neoglyco IL-1 alpha, coupled with D-mannose dimer: synthesis and biological activities in vitro.	Mannose	89-98	interleukin 1 alpha	Homo sapiens	34-53
7999926-2	1994	In order to investigate the effect of carbohydrate introduction on IL-1 activity and to develop IL-1 with less deleterious effects recombinant human IL-1 alpha was chemically coupled with mannose dimers, alpha-D-Man1-6-D-Man[Man2(alpha 1,6)] and alpha-D-Man1-4-D-Man[Man2(alpha 1,4)].	Mannose	188-195	interleukin 1 alpha	Homo sapiens	149-159
7999926-3	1994	About 5 molecules of mannose dimers were introduced per molecule of IL-1.	Mannose	21-28	interleukin 1 alpha	Homo sapiens	68-72
7999926-5	1994	Conversely, antibody against the mannose dimer reacted with only glycosylated IL-1.	Mannose	33-40	interleukin 1 alpha	Homo sapiens	78-82
8185325-10	1994	We found high-mannose-type structures at Asn-57, Asn-82, and Asn-87 of ME20-M, whereas ME20-S contained 73% complex-type and 27% high-mannose-type oligosaccharides at the same sites.	Mannose	14-21	premelanosome protein	Homo sapiens	71-77
8048628-6	1994	These data suggest that the isoelectric and glycoform heterogeneity of active renin are, in fact, closely related and may result from variable and interrelated mannose (Con A affinity) and sialic acid (charge) attachments to renin.	Mannose	160-167	renin	Rattus norvegicus	78-83
8026463-3	1994	Two very polar [3H]mannose-labeled glycolipids named CP1 and CP2 qualified as GPI precursor lipids since their carbohydrate head group, Man alpha 1,2(X--&gt;PO4--&gt;6)Man alpha 1,2Man alpha 1,6Man alpha-GlcN-inositol (with X most likely being ethanolamine) comprises the core structure which is common to all GPI anchors described so far.	Mannose	19-26	ceruloplasmin	Homo sapiens	61-64
8195236-2	1994	Pulmonary surfactant protein D (SP-D) is a member of a family of collagenous C-type lectins that includes the serum mannose binding proteins and surfactant protein A.	Mannose	116-123	surfactant protein D	Rattus norvegicus	0-30
8195236-2	1994	Pulmonary surfactant protein D (SP-D) is a member of a family of collagenous C-type lectins that includes the serum mannose binding proteins and surfactant protein A.	Mannose	116-123	surfactant protein D	Rattus norvegicus	32-36
8034730-6	1994	Mannose-binding proteins and mannose-specific lectins of macrophages bind N-acetylmannosamine, glucose, and N-acetylglucosamine in addition to mannose, indicating that the nature and orientation of the C-2 substituent are not important to these lectins.	Mannose	0-7	complement C2	Homo sapiens	202-205
8034730-6	1994	Mannose-binding proteins and mannose-specific lectins of macrophages bind N-acetylmannosamine, glucose, and N-acetylglucosamine in addition to mannose, indicating that the nature and orientation of the C-2 substituent are not important to these lectins.	Mannose	29-36	complement C2	Homo sapiens	202-205
8034730-7	1994	In contrast, AHL shows a strict requirement for the presence of an axial hydroxyl group at the C-2 position (i.e. mannose).	Mannose	114-121	complement C2	Homo sapiens	95-98
7979173-3	1994	PS1 contains at least 50% carbohydrate, consisting mainly of glucose, galactose and mannose, and about 10% lipid that may correspond to phosphatidylinositol.	Mannose	84-91	presenilin 1	Mus musculus	0-3
8182054-3	1994	We have been investigating the basis for the specific recognition of lysosomal enzymes by UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase by using the precursor form of the lysosomal cysteine protease, cathepsin L, as a model lysosomal enzyme in an in vitro assay for mannose phosphorylation.	Mannose	276-283	cathepsin L	Homo sapiens	210-221
8185316-4	1994	By using brefeldin A to induce colocalization of the UDPGlcNAc: lysosomal enzyme N-acetylglucosamine-1-phosphotransferase with the cathepsin L proteins in the ER, it was shown that the altered proteins were not susceptible to mannose phosphorylation as they exist in the ER.	Mannose	226-233	cathepsin L	Mus musculus	131-142
8185325-10	1994	We found high-mannose-type structures at Asn-57, Asn-82, and Asn-87 of ME20-M, whereas ME20-S contained 73% complex-type and 27% high-mannose-type oligosaccharides at the same sites.	Mannose	14-21	premelanosome protein	Homo sapiens	71-75
12244255-9	1994	Depletion of phosphate from soybean cell cultures by the addition of mannose stimulated VspB expression, even in the absence of sucrose or MeJA.	Mannose	69-76	stem 31 kDa glycoprotein	Glycine max	88-92
7513210-5	1994	PMN preincubated with mannose-6-P or N-acetylneuraminic acid (sialic acid), but not mannose or galactose-6-P, showed reduced adherence to ROS-treated HUVEC, suggesting that carbohydrate molecules were expressed on the latter and served as the ligand for the PMN L-selectin.	Mannose	22-29	selectin L	Homo sapiens	262-272
12244257-6	1994	Both 2-deoxyglucose and mannose, which are phosphorylated by hexokinase but not further metabolized, specifically repressed MS and ICL gene expression relative to a third glyoxylate cycle gene, malate dehydrogenase.	Mannose	24-31	isocitrate lyase	Cucumis sativus	131-134
8135860-3	1994	The uptake of Man-SOD was inhibited significantly at a low temperature and by the presence of mannan, mannose and colchicine, demonstrating the targeted delivery of Man-SOD via mannose receptor-mediated endocytosis.	Mannose	102-109	superoxide dismutase 1	Homo sapiens	18-21
12244257-6	1994	Both 2-deoxyglucose and mannose, which are phosphorylated by hexokinase but not further metabolized, specifically repressed MS and ICL gene expression relative to a third glyoxylate cycle gene, malate dehydrogenase.	Mannose	24-31	malate dehydrogenase, cytoplasmic	Cucumis sativus	194-214
8166967-1	1994	OBJECTIVE: Swainsonine (SW), an inhibitor of mammalian Golgi alpha-mannosidase II, blocks the processing of high mannose to complex type oligosaccharides.	Mannose	113-120	mannosidase alpha class 2A member 1	Homo sapiens	55-81
8054845-5	1994	The bound FVIII was specifically dissociated from LCA-Sepharose by methyl-alpha-D-mannopyranoside, and to a lesser extent by other monosaccharides such as D-glucose, methyl-alpha-D-glucopyranoside, D-mannose, and D-galactose.	Mannose	198-207	coagulation factor VIII	Homo sapiens	10-15
8131846-1	1994	A folding topology for the homodimeric N-terminal domain (IIA, 2 x 14 kDa) of the hydrophilic subunit (IIABman) of the mannose transporter of E. coli is proposed.	Mannose	119-126	colicin Ia immunity protein	Escherichia coli	58-61
8135860-3	1994	The uptake of Man-SOD was inhibited significantly at a low temperature and by the presence of mannan, mannose and colchicine, demonstrating the targeted delivery of Man-SOD via mannose receptor-mediated endocytosis.	Mannose	102-109	superoxide dismutase 1	Homo sapiens	169-172
8106376-9	1994	Competition experiments showed that mannose or mannan effectively impaired Man9 binding to the cells, whereas galactose or fucose was ineffective.	Mannose	36-43	mannosidase alpha class 1A member 1	Homo sapiens	75-79
8177372-5	1994	Chronic exposure of neuroblastoma cells to media containing 30 mM glucose, galactose, or mannose caused a significant decrease in Na+/K+ ATPase transport activity, resting membrane potential, and bradykinin-stimulated 32P incorporation into phosphatidylinositol compared to cells cultured in medium containing 30 mM fructose.	Mannose	89-96	kininogen 1	Homo sapiens	196-206
8110797-10	1994	Double-labeling experiments using 3H-mannose and 35S-methionine showed that cellular apoB contained twice the amount of mannose as medium apoB.	Mannose	37-44	apolipoprotein B	Rattus norvegicus	85-89
7906143-11	1994	In contrast to the other brush border enzymes studied, lactase-phlorizin hydrolase (EC 3.2.1.23-62) was found to occur predominantly as a monomer in its transient, high mannose-glycosylated state.	Mannose	169-176	lactase phlorizin hydrolase	Sus scrofa	55-82
7954662-12	1994	The effect of acetylcholinesterase depended on the presence of divalent cations and was inhibited by mannan and D-mannose, but not D-galactose.	Mannose	112-121	acetylcholinesterase	Rattus norvegicus	14-34
8119690-3	1994	In vivo pulse-chase experiments, followed by subcellular fractionation of the liver and immunoprecipitation, showed that B10 is first synthesized as a high-mannose form of 123 kD and then matured to a complex glycosylated form of 130 kD, which peaks in the Golgi apparatus after 15 min of chase and reaches the plasma membrane with a half-time of 30 to 45 min.	Mannose	156-163	ectonucleotide pyrophosphatase/phosphodiesterase 3	Rattus norvegicus	121-124
8180600-4	1994	The lectin affinity of the carbohydrate moiety of lymphoblast CD9 antigen would indicate the presence of N-linked oligosaccharide chains having groups of N-acetyl glucosamine residues, a mannose core and a terminal D-galactose.	Mannose	187-194	CD9 molecule	Homo sapiens	62-65
8289826-15	1994	We have also shown that mannose, a sugar that can be metabolized by the beta cell, mimics the effects of glucose in the in vivo transfection assays and the in vitro RIPE3b1 binding assays.	Mannose	24-31	MAF bZIP transcription factor A	Homo sapiens	165-172
8025258-1	1994	Insulin-like growth factor II/mannose-6-phosphate (IGF II/Man-6-P) receptors participate in the trafficking of lysosomal enzymes and also in the transduction of the effects of the growth factor via transmembrane-anchored receptor protein.	Mannose	30-37	insulin like growth factor 2	Homo sapiens	51-57
8296163-4	1994	IgA2 myeloma proteins reacted more strongly than IgA1 with the mannose-specific lectin ConA, whereas IgA1 myeloma proteins reacted more strongly than IgA2 with two galactose-specific lectins, Ricinus communis agglutinin I and Abrus precatorius agglutinin.	Mannose	63-70	immunoglobulin heavy constant alpha 1	Homo sapiens	49-53
7507484-5	1994	In vitro translation of UPII mRNA demonstrated that UPII is indeed first synthesized as a 19-kDa precursor, which loses its signal peptide upon insertion into added microsomes; this process is accompanied by the acquisition of high mannose-type oligosaccharides giving rise to a 28-kDa precursor which is completely protected from the digestion by exogenous proteases.	Mannose	232-239	uroplakin 2	Bos taurus	24-28
7507484-5	1994	In vitro translation of UPII mRNA demonstrated that UPII is indeed first synthesized as a 19-kDa precursor, which loses its signal peptide upon insertion into added microsomes; this process is accompanied by the acquisition of high mannose-type oligosaccharides giving rise to a 28-kDa precursor which is completely protected from the digestion by exogenous proteases.	Mannose	232-239	uroplakin 2	Bos taurus	52-56
7802430-8	1994	Three different forms of the LH receptor are physiologically expressed: a mature 85 kDa transmembrane species, a 68 kDa high mannose containing species corresponding to a precursor which accumulate inside the cells, and truncated 45-48 kDa molecular weight species corresponding to the variant messenger RNAs identified during the cloning of the receptor.	Mannose	125-132	luteinizing hormone/choriogonadotropin receptor	Homo sapiens	29-40
7508462-4	1994	Quantitative monosaccharide analysis showed that Fel d I was a glycoprotein, containing high levels of fucose, as well as glucosamine, galactose, and mannose.	Mannose	150-157	major allergen I polypeptide chain 2	Felis catus	49-56
7504531-11	1994	Some receptors, for example the mannose and Fc gamma-receptors, are particularly well suited to direct particles to phagolysosomes and trigger a respiratory burst, whereas other receptors, for example the CR1, may not.	Mannose	32-39	complement C3b/C4b receptor 1 (Knops blood group)	Homo sapiens	205-208
8253757-5	1993	Analysis of the delta och1 mnn1 strain oligosaccharides released from total cell mannoprotein revealed that the delta och1 mnn1 mutant eliminates the alpha-1,3-mannose attached to the core and accumulates predominantly a single ER-form oligosaccharide species (Man8GlcNAc2), suggesting a potential use of this strain as a host cell to produce glycoproteins containing mammalian high mannose type oligosaccharides.	Mannose	160-167	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	118-122
8106294-11	1994	IAP in normal mouse was rich in high-mannose type sugar chain (Peak 3) and contained no hybrid-type sugar chain (Peak 4), which was present in inflammatory and tumor-induced IAP.	Mannose	37-44	magnesium transporter 1	Mus musculus	0-3
8253757-5	1993	Analysis of the delta och1 mnn1 strain oligosaccharides released from total cell mannoprotein revealed that the delta och1 mnn1 mutant eliminates the alpha-1,3-mannose attached to the core and accumulates predominantly a single ER-form oligosaccharide species (Man8GlcNAc2), suggesting a potential use of this strain as a host cell to produce glycoproteins containing mammalian high mannose type oligosaccharides.	Mannose	160-167	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	123-127
7504980-6	1993	Mannose, glucose, fucose, and N-acetylglucosamine inhibit HPRG-induced MOLT-3 cell attachment to different degrees, with methyl alpha-D-mannopyranoside being the most potent inhibitor.	Mannose	0-7	histidine rich glycoprotein	Homo sapiens	58-62
8286783-4	1993	Binding of unlabeled SP-A depends on the presence of calcium ions in the medium and involves a mannose-specific mechanism.	Mannose	95-102	surfactant protein A1	Rattus norvegicus	21-25
8256512-4	1993	One member of this gene family, KRE2 (also known as MNT1; Hausler and Robbins, 1992), encodes an alpha-1,2 mannosyltransferase which adds the third mannose onto O-linked glycoprotein side-chains (Hausler et al., 1992).	Mannose	148-155	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	32-36
8222314-1	1993	The IgG of patients with rheumatoid arthritis and mice with pristane induced arthritis (PIA) tends to lack the terminal galactose normally on the conserved N-acetylglucosamine linked beta 1-2 to mannose in IgG.	Mannose	195-202	hemoglobin, beta adult major chain	Mus musculus	183-191
8144855-2	1993	These lectins allowed the isolation of PRL glycoforms containing either biantennary, mannose-rich or fucosylated complex carbohydrate structures, respectively.	Mannose	85-92	prolactin	Homo sapiens	39-42
8144855-3	1993	Endoglycosidase treatment and carbohydrate content of PRL was found to be consistent with N-linked oligosaccharides of mannose-rich structure and complex units terminated in sialic acid.	Mannose	119-126	prolactin	Homo sapiens	54-57
8144855-4	1993	Mannose-rich PRL and PRL with biantennary oligosaccharides promoted cell growth of rat lymphoma cells to a diminished extent compared to non-glycosylated PRL (NG-PRL), indicating that the two major types of carbohydrate structure are able to decrease the intrinsic bioactivity of PRL.	Mannose	0-7	prolactin	Rattus norvegicus	13-16
8223597-1	1993	Man9-mannosidase, a processing enzyme found in the endoplasmic reticulum (ER), catalyses the removal of three distinct mannose residues from peptide-bound Man9-GlcNAc2 oligosaccharides producing a single Man6 isomer [Bause, E., Breuer, W., Schweden, J., Roesser, R. &amp; Geyer, R. (1992) Eur.	Mannose	119-126	mannosidase alpha class 1A member 1	Homo sapiens	0-16
8223597-1	1993	Man9-mannosidase, a processing enzyme found in the endoplasmic reticulum (ER), catalyses the removal of three distinct mannose residues from peptide-bound Man9-GlcNAc2 oligosaccharides producing a single Man6 isomer [Bause, E., Breuer, W., Schweden, J., Roesser, R. &amp; Geyer, R. (1992) Eur.	Mannose	119-126	mannosidase alpha class 1A member 1	Homo sapiens	0-4
8240280-9	1993	Upon insulin stimulation of fat cells in the presence of 2.5 mM mannose, the release of 3-O-methylglucose-transport-stimulating activity was detected (for purified supernatant of adipocytes without insulin, 6.9 +/- 1.12%; with insulin, 41.0 +/- 3.6%) and lipogenesis-stimulating activity (without insulin, 0.93 +/- 0.17, with insulin 2.96 +/- 0.31 nmol/min per mg).	Mannose	64-71	insulin	Homo sapiens	5-12
8240280-9	1993	Upon insulin stimulation of fat cells in the presence of 2.5 mM mannose, the release of 3-O-methylglucose-transport-stimulating activity was detected (for purified supernatant of adipocytes without insulin, 6.9 +/- 1.12%; with insulin, 41.0 +/- 3.6%) and lipogenesis-stimulating activity (without insulin, 0.93 +/- 0.17, with insulin 2.96 +/- 0.31 nmol/min per mg).	Mannose	64-71	insulin	Homo sapiens	198-205
8240280-9	1993	Upon insulin stimulation of fat cells in the presence of 2.5 mM mannose, the release of 3-O-methylglucose-transport-stimulating activity was detected (for purified supernatant of adipocytes without insulin, 6.9 +/- 1.12%; with insulin, 41.0 +/- 3.6%) and lipogenesis-stimulating activity (without insulin, 0.93 +/- 0.17, with insulin 2.96 +/- 0.31 nmol/min per mg).	Mannose	64-71	insulin	Homo sapiens	198-205
8240280-9	1993	Upon insulin stimulation of fat cells in the presence of 2.5 mM mannose, the release of 3-O-methylglucose-transport-stimulating activity was detected (for purified supernatant of adipocytes without insulin, 6.9 +/- 1.12%; with insulin, 41.0 +/- 3.6%) and lipogenesis-stimulating activity (without insulin, 0.93 +/- 0.17, with insulin 2.96 +/- 0.31 nmol/min per mg).	Mannose	64-71	insulin	Homo sapiens	198-205
8240280-9	1993	Upon insulin stimulation of fat cells in the presence of 2.5 mM mannose, the release of 3-O-methylglucose-transport-stimulating activity was detected (for purified supernatant of adipocytes without insulin, 6.9 +/- 1.12%; with insulin, 41.0 +/- 3.6%) and lipogenesis-stimulating activity (without insulin, 0.93 +/- 0.17, with insulin 2.96 +/- 0.31 nmol/min per mg).	Mannose	64-71	insulin	Homo sapiens	198-205
8144855-11	1993	NG-PRL and mannose-rich G-PRL showed higher incorporation in liver than biantennary G-PRL which was preferentially eliminated by the kidney.	Mannose	11-18	prolactin	Homo sapiens	26-29
8144855-11	1993	NG-PRL and mannose-rich G-PRL showed higher incorporation in liver than biantennary G-PRL which was preferentially eliminated by the kidney.	Mannose	11-18	prolactin	Homo sapiens	26-29
8215389-5	1993	The reactivity of endoglycosidase H and N-glycanase and analysis of phosphorylation indicated that both precursor and mature cathepsin C are phosphorylated and N-glycosylated to give a high-mannose-type.	Mannose	190-197	cathepsin C	Rattus norvegicus	125-136
8216218-9	1993	3-O-Methylglucose, D-galactose, D-fructose, D-mannose and D-xylose can mimic the regulatory effect of glucose on the SGLT1 mRNA level in rat jejunum.	Mannose	44-53	solute carrier family 5 member 1	Rattus norvegicus	117-122
8294138-0	1993	Activation of human monocyte/macrophage cytotoxicity by IL-2/IFN gamma is linked to increased expression of an antitumor receptor with specificity for acetylated mannose.	Mannose	162-169	interleukin 2	Homo sapiens	56-60
8294138-0	1993	Activation of human monocyte/macrophage cytotoxicity by IL-2/IFN gamma is linked to increased expression of an antitumor receptor with specificity for acetylated mannose.	Mannose	162-169	interferon gamma	Homo sapiens	61-70
8395519-10	1993	Using glycosylation inhibitors, we could determine that CISP is synthesized as a 175-kDa core protein, is then matured into a 190-kDa high-mannose form and secreted as a 195-kDa mature protein.	Mannose	139-146	thrombospondin 2	Bos taurus	56-60
8256512-4	1993	One member of this gene family, KRE2 (also known as MNT1; Hausler and Robbins, 1992), encodes an alpha-1,2 mannosyltransferase which adds the third mannose onto O-linked glycoprotein side-chains (Hausler et al., 1992).	Mannose	148-155	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	52-56
8256512-5	1993	In contrast to KRE2 null mutants, which produce shortened (two-mannose) chains, mutants harboring a KTR2 gene disruption synthesize O-linked chains with the wild-type patterns of five mannose residues.	Mannose	184-191	mannosyltransferase KTR2	Saccharomyces cerevisiae S288C	100-104
8352755-6	1993	The order of inhibiting potency on the binding of SP-A was: N-acetylmannosamine &gt; L-fucose, maltose &gt; glucose &gt; mannose.	Mannose	121-128	surfactant protein A2	Homo sapiens	50-54
8060671-4	1993	The commercial Endo F-peptide N-glycosidase/glycanyl amidase (PNGase) mixture readily cleaved high mannose and complex oligosaccharides (neutral and sialyated) with common core alpha 1-6 linked fucose found in porcine thyroglobulin including the trimannosyl-chitobiose core structure.	Mannose	99-106	N-glycanase 1	Homo sapiens	20-60
8060671-4	1993	The commercial Endo F-peptide N-glycosidase/glycanyl amidase (PNGase) mixture readily cleaved high mannose and complex oligosaccharides (neutral and sialyated) with common core alpha 1-6 linked fucose found in porcine thyroglobulin including the trimannosyl-chitobiose core structure.	Mannose	99-106	N-glycanase 1	Homo sapiens	62-68
8352560-0	1993	Induction of NK-like activity in T cells by IL-2/anti-CD3 is linked to expression of a new antitumour receptor with specificity for acetylated mannose.	Mannose	143-150	interleukin 2	Homo sapiens	44-48
8373631-0	1993	Human serum mannose binding protein (MBP): development of an enzyme-linked immunosorbent assay (ELISA) and determination of levels in serum from 1085 normal Japanese and in some body fluids.	Mannose	12-19	myelin basic protein	Homo sapiens	37-40
8103073-4	1993	Our results suggest that CD11b and CD18 (receptors for C3bi) serve also as receptors for mannose-specific E. coli on human peritoneal macrophages and may be involved in the lectinophagocytosis of the bacteria by these cells.	Mannose	89-96	integrin subunit alpha M	Homo sapiens	25-30
8103073-4	1993	Our results suggest that CD11b and CD18 (receptors for C3bi) serve also as receptors for mannose-specific E. coli on human peritoneal macrophages and may be involved in the lectinophagocytosis of the bacteria by these cells.	Mannose	89-96	integrin subunit beta 2	Homo sapiens	35-39
8314788-6	1993	The recombinant cytochrome b558 beta-subunit was heterogeneously N-glycosylated as demonstrated by its susceptibility to cleavage with endoglycosidases F and H. In contrast to the neutrophil cytochrome b558, a portion of the N-linked oligosaccharide was of the high mannose type.	Mannose	266-273	CYTB	Spodoptera frugiperda	16-28
8393658-7	1993	Arabinose, xylose, mannose, ribose, fructose and glucose 6-phosphate (but not mannitol) were also able to inactive the ATPase.	Mannose	19-26	dynein axonemal heavy chain 8	Homo sapiens	119-125
8099781-4	1993	(ii) Brefeldin A completely inhibited the transport of all [3H]mannose-labeled proteins releasable by phosphatidylinositol-specific phospholipase C, including Thy-1, to the surface of BN-1010-1 cells.	Mannose	63-70	Thy-1 cell surface antigen	Rattus norvegicus	159-164
8513967-2	1993	The inactivation of glucokinase by glyceraldehyde was blocked by the presence of its substrates such as glucose and mannose.	Mannose	116-123	glucokinase	Rattus norvegicus	20-31
8099781-2	1993	(i) Tunicamycin completely inhibited mannose incorporation into Thy-1.	Mannose	37-44	Thy-1 cell surface antigen	Rattus norvegicus	64-69
8503188-1	1993	We have studied perturbation of the gp120/gp41 envelope complex of HIV-1 in the presence of the mannose-specific lectin succinyl Con A (SC) and compared the effect with that observed in the presence of soluble CD4 (sCD4).	Mannose	96-103	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	36-41
8503188-8	1993	These results suggest that although interacting with different regions of gp120, the mannose-specific lectin alters the conformation of the glycoprotein in a manner similar to that induced by sCD4, causing destabilization of the gp120/gp41 complex.	Mannose	85-92	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	74-79
21573632-4	1993	Results indicate MCA 1315 derived OFA possesses N-glycosylated oligosaccharide chains which are high in mannose.	Mannose	104-111	oncofetal antigen	Mus musculus	34-37
8503188-8	1993	These results suggest that although interacting with different regions of gp120, the mannose-specific lectin alters the conformation of the glycoprotein in a manner similar to that induced by sCD4, causing destabilization of the gp120/gp41 complex.	Mannose	85-92	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	229-234
8486682-4	1993	Bound conglutinin was eluted with GlcNAc, and then the 43-kDa lectin, together with mannan-binding protein (MBP), was eluted with mannose.	Mannose	130-137	mannose binding lectin 2	Bos taurus	108-111
8486682-12	1993	An inhibition assay with biotinylated CL-43, using solid-phase mannan as ligand, revealed the following carbohydrate inhibition pattern: mannose and ManNAc &gt; fucose &gt; GlcNAc &gt; glucose and maltose &gt; galactose &gt; lactose &gt;&gt; GalNAc.	Mannose	137-144	collectin-43	Bos taurus	38-43
21573632-5	1993	This result is in agreement with the high mannose glycosylation of OFA derived from 13-day mouse fetuses.	Mannose	42-49	oncofetal antigen	Mus musculus	67-70
8487290-5	1993	coli H21 was inhibited by prior injection of mannose into mice, suggesting that the clearance of this strain was mediated by mannose-type lectin on the surface of tissue macrophages.	Mannose	45-52	histocompatibility 21	Mus musculus	5-8
8486762-1	1993	Mannose-terminated glucocerebrosidase (alglucerase; Ceredase) was designed for enzyme replacement therapy in Gaucher disease to take advantage of mannose receptor-mediated endocytosis by macrophages.	Mannose	0-7	glucosylceramidase beta	Homo sapiens	39-50
8486762-4	1993	The fact that the binding of alglucerase by macrophages was mediated principally by a receptor distinct from the classical mannose receptor that binds mannose-BSA was confirmed by differential inhibitors, viz., alpha-methyl-glucoside, fucose, and mannose-BSA, and by its independence on Ca2+.	Mannose	123-130	glucosylceramidase beta	Homo sapiens	29-40
8486762-4	1993	The fact that the binding of alglucerase by macrophages was mediated principally by a receptor distinct from the classical mannose receptor that binds mannose-BSA was confirmed by differential inhibitors, viz., alpha-methyl-glucoside, fucose, and mannose-BSA, and by its independence on Ca2+.	Mannose	151-158	glucosylceramidase beta	Homo sapiens	29-40
8486762-6	1993	Endothelial cells also manifest mannose-dependent binding and uptake of alglucerase and may therefore account for a large proportion of the infused alglucerase.	Mannose	32-39	glucosylceramidase beta	Homo sapiens	72-83
8486762-6	1993	Endothelial cells also manifest mannose-dependent binding and uptake of alglucerase and may therefore account for a large proportion of the infused alglucerase.	Mannose	32-39	glucosylceramidase beta	Homo sapiens	148-159
8487290-5	1993	coli H21 was inhibited by prior injection of mannose into mice, suggesting that the clearance of this strain was mediated by mannose-type lectin on the surface of tissue macrophages.	Mannose	125-132	histocompatibility 21	Mus musculus	5-8
8463218-4	1993	Here we report a new method of expression cloning that is applicable to many mutant rodent and human cells, and its application for cloning a human cDNA termed PIG-F (for Phosphatidyl-Inositol-Glycan class F) using a Thy-1-negative mutant murine thymoma cell line of complementation class F. PIG-F takes a part in the step of transfer of ethanolamine phosphate to the GPI intermediate containing three residues of mannose.	Mannose	414-421	phosphatidylinositol glycan anchor biosynthesis class F	Sus scrofa	160-165
8463218-4	1993	Here we report a new method of expression cloning that is applicable to many mutant rodent and human cells, and its application for cloning a human cDNA termed PIG-F (for Phosphatidyl-Inositol-Glycan class F) using a Thy-1-negative mutant murine thymoma cell line of complementation class F. PIG-F takes a part in the step of transfer of ethanolamine phosphate to the GPI intermediate containing three residues of mannose.	Mannose	414-421	phosphatidylinositol glycan anchor biosynthesis class F	Sus scrofa	171-207
8428922-3	1993	N-Acetylglucosaminyltransferase V catalyzes the transfer of GlcNAc from the sugar nucleotide donor UDP-GlcNAc to the 6-OH group of mannose in the synthetic trisaccharide acceptor beta GlcNAc(1--&gt;2)alpha Man(1--&gt;6)beta Glc-O(CH2)7CH3 (Km = 23 +/- 2 microM; Vmax = 116 +/- 3 pmol/h) to form the tetrasaccharide beta GlcNAc(1--&gt;2)(beta GlcNAc(1--&gt;6))alpha Man(1--&gt;6)beta Glc-O(CH2)7CH3.	Mannose	131-138	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-33
8495969-1	1993	Escherichia coli bacteria expressing mannose-resistant fimbriae/haemagglutination induced the production of substantial amounts of tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) from a peripheral human lymphocyte, monocyte, basophil (LMB) cell suspension.	Mannose	37-44	tumor necrosis factor	Homo sapiens	161-170
8495969-1	1993	Escherichia coli bacteria expressing mannose-resistant fimbriae/haemagglutination induced the production of substantial amounts of tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) from a peripheral human lymphocyte, monocyte, basophil (LMB) cell suspension.	Mannose	37-44	interleukin 6	Homo sapiens	176-189
8495969-1	1993	Escherichia coli bacteria expressing mannose-resistant fimbriae/haemagglutination induced the production of substantial amounts of tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) from a peripheral human lymphocyte, monocyte, basophil (LMB) cell suspension.	Mannose	37-44	interleukin 6	Homo sapiens	191-195
8495969-2	1993	In this regard, E. coli bacteria with S-mannose-resistant fimbriae/haemagglutination were the most potent inducers of IL-6 and TNF-alpha secretion, followed by the E. coli strain with P-mannose-resistant fimbriae/haemagglutination.	Mannose	40-47	interleukin 6	Homo sapiens	118-122
8495969-2	1993	In this regard, E. coli bacteria with S-mannose-resistant fimbriae/haemagglutination were the most potent inducers of IL-6 and TNF-alpha secretion, followed by the E. coli strain with P-mannose-resistant fimbriae/haemagglutination.	Mannose	40-47	tumor necrosis factor	Homo sapiens	127-136
7681016-1	1993	The three-dimensional structure of the carbohydrate recognition domain of the human E-selectin endothelial-leucocyte adhesion molecule (ELAM-1) was modelled on the basis of the recently determined X-ray crystallographic structure of the homologous domain found in the rat mannose-binding protein.	Mannose	272-279	selectin E	Homo sapiens	84-94
7681016-1	1993	The three-dimensional structure of the carbohydrate recognition domain of the human E-selectin endothelial-leucocyte adhesion molecule (ELAM-1) was modelled on the basis of the recently determined X-ray crystallographic structure of the homologous domain found in the rat mannose-binding protein.	Mannose	272-279	selectin E	Homo sapiens	136-142
8439291-13	1993	It is concluded that the alpha-mannosidase encoded by MNS1 is the only enzyme responsible for mannose removal in vivo, and that this processing step is not essential for outer chain synthesis.	Mannose	94-101	alpha-mannosidase	Saccharomyces cerevisiae S288C	25-42
8439291-13	1993	It is concluded that the alpha-mannosidase encoded by MNS1 is the only enzyme responsible for mannose removal in vivo, and that this processing step is not essential for outer chain synthesis.	Mannose	94-101	mannosyl-oligosaccharide 1,2-alpha-mannosidase	Saccharomyces cerevisiae S288C	54-58
8381403-10	1993	Furthermore, WGA inhibition was not abolished although most, if not all, VIP receptor oligosaccharides were converted to high mannose type structures by treating IGR39 cells with deoxymannojirimycin.	Mannose	126-133	vasoactive intestinal peptide	Homo sapiens	73-76
8100569-6	1993	In contrast, several lectins (including mannose binding protein) bound to gp120 and blocked CD4-gp120 interactions.	Mannose	40-47	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	74-79
8100569-6	1993	In contrast, several lectins (including mannose binding protein) bound to gp120 and blocked CD4-gp120 interactions.	Mannose	40-47	CD4 molecule	Homo sapiens	92-95
8100569-6	1993	In contrast, several lectins (including mannose binding protein) bound to gp120 and blocked CD4-gp120 interactions.	Mannose	40-47	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	96-101
8466542-1	1993	The anti-inflammatory agent naproxen (Nap) was covalently coupled to human serum albumin (HSA) and to the neoglycoproteins, galactose and mannose terminated HSA, to deliver this drug selectively to different cell types of the liver.	Mannose	138-145	albumin	Homo sapiens	157-160
8501138-7	1993	Our results demonstrate that alterations in glycosylation of N-linked oligosaccharides, resulting in the synthesis of high mannose type sugars on molecules that may interact with the beta 2 integrins, leads to an increased adherence of PMA activated neutrophils to endothelial cells.	Mannose	123-130	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	183-189
8428908-5	1993	In accordance with this, "high mannose"-glycosylated alpha 1-antitrypsin was retained in or transported back to the ER.	Mannose	31-38	serpin family A member 1	Homo sapiens	53-72
8421844-1	1993	Mannan-binding protein (MBP) is a newly discovered serum protein which activates the complement system by the classical pathway by binding to mannose-rich surfaces on microorganisms.	Mannose	142-149	myelin basic protein	Homo sapiens	0-22
8380585-2	1993	This study explores the mechanism whereby ionomycin, a Ca2+ ionophore, and thapsigargin, an ER Ca(2+)-ATPase inhibitor, promote retention of alpha 1-antitrypsin (alpha 1-AT) bearing high mannose, endoglycosidase H (Endo H)-sensitive oligosaccharide side chains within the ER of HepG2 cells.	Mannose	187-194	serpin family A member 1	Homo sapiens	141-160
8380585-2	1993	This study explores the mechanism whereby ionomycin, a Ca2+ ionophore, and thapsigargin, an ER Ca(2+)-ATPase inhibitor, promote retention of alpha 1-antitrypsin (alpha 1-AT) bearing high mannose, endoglycosidase H (Endo H)-sensitive oligosaccharide side chains within the ER of HepG2 cells.	Mannose	187-194	serpin family A member 1	Homo sapiens	162-172
8416944-1	1993	Human serum (MBP) and human recombinant (rMBP) mannose-binding protein bind to mannose-rich, serum-resistant Salmonella montevideo (SH5770), enhance C3 deposition, and render the organisms serum-sensitive.	Mannose	47-54	myelin basic protein	Rattus norvegicus	41-45
8416944-1	1993	Human serum (MBP) and human recombinant (rMBP) mannose-binding protein bind to mannose-rich, serum-resistant Salmonella montevideo (SH5770), enhance C3 deposition, and render the organisms serum-sensitive.	Mannose	79-86	myelin basic protein	Homo sapiens	13-16
8416944-1	1993	Human serum (MBP) and human recombinant (rMBP) mannose-binding protein bind to mannose-rich, serum-resistant Salmonella montevideo (SH5770), enhance C3 deposition, and render the organisms serum-sensitive.	Mannose	79-86	myelin basic protein	Rattus norvegicus	41-45
7680268-0	1993	Mannose-specific lectins bind alpha-2-macroglobulin and an unknown protein from human plasma.	Mannose	0-7	alpha-2-macroglobulin	Homo sapiens	30-51
7680268-1	1993	GNA, the mannose-specific lectin from Galanthus nivalis was confirmed to bind alpha-2-macroglobulin (A2M) but another protein was copurified with A2M from total human plasma.	Mannose	9-16	alpha-2-macroglobulin	Homo sapiens	78-99
7680268-1	1993	GNA, the mannose-specific lectin from Galanthus nivalis was confirmed to bind alpha-2-macroglobulin (A2M) but another protein was copurified with A2M from total human plasma.	Mannose	9-16	alpha-2-macroglobulin	Homo sapiens	101-104
8421844-1	1993	Mannan-binding protein (MBP) is a newly discovered serum protein which activates the complement system by the classical pathway by binding to mannose-rich surfaces on microorganisms.	Mannose	142-149	myelin basic protein	Homo sapiens	24-27
1487325-1	1992	Para-aminophenyl O-alpha-D-mannopyranosyl-(1--&gt;2)-alpha-D-mannopyranosyl- (1--&gt;6)-alpha-D-mannopyranoside linked to bovine serum albumin as an antigen.	Mannose	95-111	albumin	Homo sapiens	129-142
8421063-9	1993	Using an in vitro binding assay, purified CBP bound mannose, galactose, and glucosamine-specific lectins.	Mannose	52-59	CREB binding protein	Homo sapiens	42-45
8142907-1	1993	Models of the lectin-homology domains of the human and murine low-affinity receptors for IgE (Fc epsilon RII/CD23) were built on the basis of sequence similarity with rat mannose-binding protein, the structure of which is known.	Mannose	171-178	Fc receptor, IgE, low affinity II, alpha polypeptide	Mus musculus	94-108
8142907-1	1993	Models of the lectin-homology domains of the human and murine low-affinity receptors for IgE (Fc epsilon RII/CD23) were built on the basis of sequence similarity with rat mannose-binding protein, the structure of which is known.	Mannose	171-178	Fc receptor, IgE, low affinity II, alpha polypeptide	Mus musculus	109-113
1337862-2	1992	Lactotransferrin isolated from a pool of mature bovine milk has been shown to contain N-glycosidically-linked glycans possessing N-acetylneuraminic acid, galactose, mannose, fucose, N-acetylglucosamine, and N-acetylgalactosamine.	Mannose	165-172	lactotransferrin	Bos taurus	0-16
1460044-9	1992	O-Linked glycosylation of LPH appears to occur in the Golgi apparatus, since the earliest detectable forms of LPH, the mannose-rich precursor (pro-LPH) is not O-glycosylated.	Mannose	119-126	lactase	Homo sapiens	26-29
1447191-1	1992	UDP-GlcNAc:alpha 3-D-mannoside beta 1,2-N-acetylglucosaminyltransferase I (GnTI) is an N(in)/C(out) (type II) membrane protein, localized in the medial-Golgi, that initiates the conversion of high mannose N-glycans to complex N-glycans.	Mannose	197-204	mannoside acetylglucosaminyltransferase 1	Mus musculus	0-73
1447191-1	1992	UDP-GlcNAc:alpha 3-D-mannoside beta 1,2-N-acetylglucosaminyltransferase I (GnTI) is an N(in)/C(out) (type II) membrane protein, localized in the medial-Golgi, that initiates the conversion of high mannose N-glycans to complex N-glycans.	Mannose	197-204	mannoside acetylglucosaminyltransferase 1	Mus musculus	75-79
8424457-1	1993	Surfactant protein D (SP-D) is a collagenous calcium-dependent carbohydrate-binding protein that is structurally related to the serum mannose-binding proteins and pulmonary surfactant protein A. SP-D was initially characterized as a biosynthetic product of freshly isolated rat type II cells and first purified in chemical amounts from bronchoalveolar lavage of rats with silica-induced alveolar lipoproteinosis.	Mannose	134-141	surfactant protein D	Homo sapiens	0-20
8424457-1	1993	Surfactant protein D (SP-D) is a collagenous calcium-dependent carbohydrate-binding protein that is structurally related to the serum mannose-binding proteins and pulmonary surfactant protein A. SP-D was initially characterized as a biosynthetic product of freshly isolated rat type II cells and first purified in chemical amounts from bronchoalveolar lavage of rats with silica-induced alveolar lipoproteinosis.	Mannose	134-141	surfactant protein D	Homo sapiens	22-26
8262455-5	1993	In addition, antibodies against PMM-M2+, as well as D-mannose- or N-acetyl-D-glucosamine-terminated oligosaccharides of PMM-M2+ inhibit NK R.	Mannose	52-61	tachykinin receptor 3	Homo sapiens	136-140
8262455-8	1993	The EDTA-released LAK-1 antigen, but not CD2 and CD45, interact with TNF-alpha and cell surface via a mannose-inhibitable interaction dependent on the presence of Ca2+ ions.	Mannose	102-109	terminal nucleotidyltransferase 4A	Homo sapiens	18-23
8262455-8	1993	The EDTA-released LAK-1 antigen, but not CD2 and CD45, interact with TNF-alpha and cell surface via a mannose-inhibitable interaction dependent on the presence of Ca2+ ions.	Mannose	102-109	tumor necrosis factor	Homo sapiens	69-78
1493050-7	1992	Digestion of immunoprecipitated gp120 and gp160 with endoglycosidase H and peptide N-glycosidase F revealed that the envelope glycoprotein in transfected L cells possessed both high mannose and complex N-glycans, analogous to the posttranslational modification of the mature envelope glycoprotein in infected T cells.	Mannose	182-189	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	32-37
1493050-7	1992	Digestion of immunoprecipitated gp120 and gp160 with endoglycosidase H and peptide N-glycosidase F revealed that the envelope glycoprotein in transfected L cells possessed both high mannose and complex N-glycans, analogous to the posttranslational modification of the mature envelope glycoprotein in infected T cells.	Mannose	182-189	endogenous retrovirus group K member 20	Homo sapiens	117-138
1446746-1	1992	Lactase is synthesized as a high-mannose large precursor (200 kDa) which is subsequently complex-glycosylated (215 kDa) and split into the 150 kDa mature form.	Mannose	33-40	lactase-phlorizin hydrolase	Oryctolagus cuniculus	0-7
1460414-1	1992	Serum mannose-binding protein (MBP) is a C-type lectin that binds to terminal mannose and N-acetylglucosamine moieties present on surfaces of certain pathogens and activates the classical complement pathway.	Mannose	6-13	myelin basic protein	Homo sapiens	31-34
1460414-1	1992	Serum mannose-binding protein (MBP) is a C-type lectin that binds to terminal mannose and N-acetylglucosamine moieties present on surfaces of certain pathogens and activates the classical complement pathway.	Mannose	78-85	myelin basic protein	Homo sapiens	31-34
1429701-1	1992	The enzyme rhodanese (thiosulfate sulfurtransferase, EC 2.8.1.1) is inactivated on incubation with reducing sugars such as glucose, mannose, or fructose, but is stable with non-reducing sugars or related polyhydroxy compounds.	Mannose	132-139	thiosulfate sulfurtransferase	Homo sapiens	22-51
1482662-4	1992	Fast atom bombardment mass spectrometry analysis showed the presence of high mannose type and hybrid type oligosaccharides in the HEMPAS transferrin which is in contrast to the complex-type oligosaccharides found in the normal transferrin.	Mannose	77-84	transferrin	Homo sapiens	137-148
1390756-5	1992	In the wild type, we found the same basic structure but more [formula; see text] than 90% of the molecules were modified with one to four alpha-(1--&gt;3)-linked mannoses, which were absent in the strains bearing the mnn1 mutation (structure C).	Mannose	162-170	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	217-221
1445299-1	1992	Human placental annexin I and annexin II were shown to be glycosylated by one-dimensional affinity blotting with the lectin concanavalin A, which recognizes D-mannose and D-glucose residues.	Mannose	157-166	annexin A2	Homo sapiens	30-40
1390756-8	1992	In both mnn1 and wild type 10-15% of the oligosaccharides had an extra alpha-(1--&gt;6)-linked mannose in the outer chain, a structure described in the recently isolated vrg1 mutant [Ballou, L., Hitzeman, R.A., Lewis, M. S., &amp; Ballou, C. E. (1991) Proc.	Mannose	95-102	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	8-12
1518869-9	1992	Collectively, these data demonstrate that the gp120-binding protein is a membrane-associated mannose-binding lectin.	Mannose	93-100	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	46-51
1516707-1	1992	Homogeneous preparations of bovine tryptophanyl-tRNA synthetase (EC 6.1.1.2) contain monosaccharides (mannose, fucose, galactose, N-acetylglucosamine) as revealed by liquid chromatography.	Mannose	102-109	tryptophanyl-tRNA synthetase 1	Bos taurus	35-63
1518869-8	1992	gp120 binding is high affinity (kd, 1.3-1.6 nM) and inhibited by mannan, D-mannose, and L-fucose; once bound, gp120 is internalized rapidly.	Mannose	73-82	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	0-5
1518869-8	1992	gp120 binding is high affinity (kd, 1.3-1.6 nM) and inhibited by mannan, D-mannose, and L-fucose; once bound, gp120 is internalized rapidly.	Mannose	73-82	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	110-115
1326943-7	1992	Biosynthetic labelling experiments in intestinal tissue explants demonstrated that the 184,000-M(r) protein is generated from a single-polypeptide, mannose-rich precursor of ACE (M(r) 175,000) by modification of the carbohydrate side-chains in the Golgi apparatus.	Mannose	148-155	angiotensin I converting enzyme	Homo sapiens	174-177
1386213-6	1992	HLBP14 was eluted from a murine laminin column by lactose, N-acetyllactosamine, and galactose but not by other control saccharides, including glucose, fucose, mannose, and melibiose.	Mannose	159-166	galectin 1	Homo sapiens	0-6
1523886-8	1992	Production of the active form of human tissue-type plasminogen activator was increased in the och1 mutant compared with the parental strain, suggesting the potential advantage of this mutant for the production of mammalian-type glycoproteins which lack mannose outer chains in yeast.	Mannose	253-260	plasminogen activator, tissue type	Homo sapiens	39-72
1628616-1	1992	The Saccharomyces cerevisiae och1 mutant shows a deficiency in the mannose outer chain elongation at the non-permissive temperature.	Mannose	67-74	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	29-33
1628616-4	1992	The OCH1 gene disruptant is not lethal but ts for cell growth, and lacks mannose outer chains.	Mannose	73-80	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	4-8
1634623-3	1992	SP-D exhibits Ca(++)-dependent carbohydrate binding in vitro and is structurally related to the collagenous C-type lectins, including serum conglutinin, serum mannose-binding proteins, and surfactant protein A.	Mannose	159-166	surfactant protein D	Rattus norvegicus	0-4
1380928-5	1992	The rhCG beta was found to contain high mannose type N-linked carbohydrates and 3-4 serine-linked disaccharide chains.	Mannose	40-47	Rh family C glycoprotein	Homo sapiens	4-8
1380928-11	1992	The antibodies held on the ovalbumin affinity adsorbent were specific for the high mannose type carbohydrates such as those present in rhCG beta, rhCG and thyroglobulin and failed to react with transferrin, alpha 1-acid glycoprotein and hCG alpha, all containing complex type carbohydrates.	Mannose	83-90	Rh family C glycoprotein	Homo sapiens	135-139
1322137-4	1992	A stimulatory effect on preproinsulin mRNA levels was also observed in response to mannose and to 4-methyl-2-oxopentanoate.	Mannose	83-90	insulin	Homo sapiens	24-37
1322137-12	1992	Other metabolites (mannose, 4-methyl-2-oxopentanoate and leucine plus glutamine) were also able to increase insulin promoter-driven CAT expression, but galactose and arginine were ineffective.	Mannose	19-26	insulin	Homo sapiens	108-115
1352293-2	1992	The correct intracellular sorting of lysosomal enzymes such as arylsulfatase A depends on the presence of mannose 6-phosphate residues on high mannose type oligosaccharides.	Mannose	106-113	arylsulfatase A	Homo sapiens	63-78
1379912-2	1992	Alglucerase is a mannose-terminated form of human placental glucocerebrosidase, developed to treat patients with Gaucher"s disease.	Mannose	17-24	glucosylceramidase beta	Homo sapiens	0-11
1377774-6	1992	Deletion of the PMI40 coding sequence results in a strain requiring D-mannose for growth.	Mannose	68-77	mannose-6-phosphate isomerase PMI40	Saccharomyces cerevisiae S288C	16-21
1377774-7	1992	The PMI40 gene is located on chromosome V, and its transcription is increased 12-fold when cells are grown on D-mannose as sole carbon source instead of D-glucose.	Mannose	110-119	mannose-6-phosphate isomerase PMI40	Saccharomyces cerevisiae S288C	4-9
1523886-8	1992	Production of the active form of human tissue-type plasminogen activator was increased in the och1 mutant compared with the parental strain, suggesting the potential advantage of this mutant for the production of mammalian-type glycoproteins which lack mannose outer chains in yeast.	Mannose	253-260	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	94-98
1318335-5	1992	C1q coated to microtiter wells induced O2- release, which occurred microtiter wells induced O2- release, which occurred after a lag period of 10 to 20 min, and was then sustained over approximately 1 h. O2- production could be triggered by the purified pepsin-resistant, collagen-like fragment of C1q, but not by mannose-binding protein and pulmonary surfactant protein A, proteins that also contain collagen-like domains.	Mannose	313-320	complement C1q A chain	Homo sapiens	0-3
1318035-12	1992	We conclude from these data that clearance of t-PA by the liver is regulated by at least two pathways, one on parenchymal cells (not galactose/mannose-mediated) and another on liver endothelial cells (mediated by a mannose receptor).	Mannose	143-150	plasminogen activator, tissue type	Rattus norvegicus	46-50
1318035-5	1992	Association of 125I-t-PA with liver endothelial cells was Ca(2+)-dependent and mannose-specific, since ovalbumin (a mannose-terminated glycoprotein) inhibited the cell association of t-PA.	Mannose	79-86	plasminogen activator, tissue type	Rattus norvegicus	20-24
1596516-7	1992	The carbohydrate insulin secretagogues mannose and D-glyceraldehyde have also been found to induce islet PGE2 release, but the non-secretagogue carbohydrates L-glucose and lactate do not.	Mannose	39-46	insulin	Homo sapiens	17-24
1316682-2	1992	Characterization of the processing events involved in the maturation of E2/NS1 revealed that a high-mannose form resident in the endoplasmic reticulum was the most abundant form detected intracellularly.	Mannose	100-107	influenza virus NS1A binding protein	Homo sapiens	75-78
1577805-4	1992	The narrow specificity of the novel mannosidase contrasts sharply with that of the major lysosomal alpha-mannosidase, which is able to catalyze the degradation of oligosaccharides containing diverse linkage and branching patterns of the mannose residues.	Mannose	237-244	mannosidase alpha class 2B member 1	Homo sapiens	89-116
1601034-4	1992	218: 625) and showed that C1qR interacts with the ligands C1q, mannose-binding protein, conglutinin and lung surfactant protein A (SP-A) (Malhotra, R., Thiel, S., Reid, K. B. M. and Sim, R. B., J. Exp.	Mannose	63-70	CD93 molecule	Homo sapiens	26-30
1601034-4	1992	218: 625) and showed that C1qR interacts with the ligands C1q, mannose-binding protein, conglutinin and lung surfactant protein A (SP-A) (Malhotra, R., Thiel, S., Reid, K. B. M. and Sim, R. B., J. Exp.	Mannose	63-70	complement C1q A chain	Homo sapiens	26-29
1500417-3	1992	LGP85 contains about 22.8% carbohydrate and the carbohydrate moiety is composed of mannose, galactose, fucose, glucosamine, galactosamine, and neuraminic acid, in a molar ratio of 40:20:2:23:3:13.	Mannose	83-90	scavenger receptor class B, member 2	Rattus norvegicus	0-5
1577827-10	1992	A recombinant carbohydrate recognition domain (CRD) of human SP-A inhibits the binding of human SP-A to galactosyl ceramide and to galactose- and mannose-bovine serum albumin, indicating that the CRD is directly involved in the binding of SP-A to these ligands.	Mannose	146-153	surfactant protein A1	Homo sapiens	61-65
1577827-10	1992	A recombinant carbohydrate recognition domain (CRD) of human SP-A inhibits the binding of human SP-A to galactosyl ceramide and to galactose- and mannose-bovine serum albumin, indicating that the CRD is directly involved in the binding of SP-A to these ligands.	Mannose	146-153	surfactant protein A1	Homo sapiens	96-100
1577827-10	1992	A recombinant carbohydrate recognition domain (CRD) of human SP-A inhibits the binding of human SP-A to galactosyl ceramide and to galactose- and mannose-bovine serum albumin, indicating that the CRD is directly involved in the binding of SP-A to these ligands.	Mannose	146-153	surfactant protein A1	Homo sapiens	96-100
1555586-9	1992	Placental transferrin receptor from donor B predominantly carried triantennary N-acetyllactosaminic glycans without fucose and hybrid-type oligosaccharides with four or five mannose residues.	Mannose	174-181	transferrin	Homo sapiens	10-21
1500095-0	1992	Identical point mutation leading to low levels of mannose binding protein and poor C3b mediated opsonisation in Chinese and Caucasian populations.	Mannose	50-57	endogenous retrovirus group K member 3	Homo sapiens	83-86
1500095-1	1992	A common opsonic defect occurring in 7% of the Caucasian population is associated with low serum levels of the lectin mannose binding protein (MBP).	Mannose	118-125	myelin basic protein	Homo sapiens	143-146
16668874-0	1992	NO(3) Enhances the Kinase Activity for Phosphorylation of Phosphoenolpyruvate Carboxylase and Sucrose Phosphate Synthase Proteins in Wheat Leaves: Evidence from the Effects of Mannose and Okadaic Acid.	Mannose	176-183	phosphoenolpyruvate carboxylase 2	Triticum aestivum	58-89
16668874-4	1992	Mannose at 50 mm, by blocking the kinase reaction, inhibited the processes of NO(3) (-)-dependent phosphoenolpyruvate carboxylase activation and sucrose phosphate synthase deactivation.	Mannose	0-7	phosphoenolpyruvate carboxylase 2	Triticum aestivum	98-129
16668874-5	1992	Following the addition of mannose, the deactivation of phosphoenolpyruvate carboxylase and the activation of sucrose phosphate synthase, both due to the enzyme-protein dephosphorylation, were at the same rate in low-NO(3) (-) and high-NO(3) (-) leaves, indicating that NO(3) (-) had no effect per se on the enzyme-protein phosphatase activity.	Mannose	26-33	phosphoenolpyruvate carboxylase 2	Triticum aestivum	55-86
1556130-8	1992	LPL was active and secreted when trimming of the mannose residues was inhibited by deoxymannojirimycin and when addition of complex sugars was blocked using Chinese hamster ovary mutants (lec1 and lec2), indicating that these processing events are not necessary for the expression of a functional enzyme.	Mannose	49-56	LOW QUALITY PROTEIN: lipoprotein lipase	Cricetulus griseus	0-3
1518562-5	1992	Endoglycosidase H or F, capable of removing high-mannose and biantennary branched N-linked oligosaccharides, produced a 2-3 kDa decrease in the molecular weight of both NEP 1 and NEP 2.	Mannose	49-56	membrane metallo-endopeptidase	Rattus norvegicus	169-172
1518562-5	1992	Endoglycosidase H or F, capable of removing high-mannose and biantennary branched N-linked oligosaccharides, produced a 2-3 kDa decrease in the molecular weight of both NEP 1 and NEP 2.	Mannose	49-56	membrane metallo-endopeptidase-like 1	Rattus norvegicus	179-184
1488862-1	1992	A therapeutic trial with mannose given intravenously as a 5% solution during 7 consecutive days (daily doses 12.5 g, 25 g and 50 g) was performed in a GPI deficient girl with nonspherocytic hemolytic anemia.	Mannose	25-32	glucose-6-phosphate isomerase	Homo sapiens	151-154
1531653-8	1992	Based on the substrate specificity and colocalization with GlcNAc-1-P transferase, the phosphate methyltransferase is likely to be responsible for the generation of mannose-6-phosphomethyldiester on Dictyostelium oligosaccharides.	Mannose	165-172	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	59-81
1740441-5	1992	Ionomycin blocked processing of alpha 1-antitrypsin at the conversion from the high mannose to the complex glycosylated form without affecting ATP or GTP contents.	Mannose	84-91	serpin family A member 1	Homo sapiens	32-51
1370485-5	1992	Bio-Gel P6 chromatography shows that TSH increases the complex type carbohydrate chains while decreasing the high mannose chains in the secreted thyroglobulin.	Mannose	114-121	thyroglobulin	Rattus norvegicus	145-158
1561701-0	1992	Modulation of interleukin-1 induced thymocyte proliferation by D-mannose.	Mannose	63-72	interleukin 1 alpha	Homo sapiens	14-27
1561701-2	1992	The monosaccharide, D-mannose (4-10 mM), significantly inhibited thymocyte proliferation induced by recombinant interleukin-1 (rIL-1).	Mannose	20-29	interleukin 1 alpha	Homo sapiens	112-125
1561701-3	1992	Mannose also inhibited the proliferation response to native, human IL-1.	Mannose	0-7	interleukin 1 alpha	Homo sapiens	67-71
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	18-25	thyroglobulin	Rattus norvegicus	51-64
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	18-25	thyroglobulin	Rattus norvegicus	97-110
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	18-25	thyroglobulin	Rattus norvegicus	97-110
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	18-25	thyroglobulin	Rattus norvegicus	97-110
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	120-127	thyroglobulin	Rattus norvegicus	97-110
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	120-127	thyroglobulin	Rattus norvegicus	97-110
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	120-127	thyroglobulin	Rattus norvegicus	97-110
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	120-127	thyroglobulin	Rattus norvegicus	97-110
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	120-127	thyroglobulin	Rattus norvegicus	97-110
1370485-4	1992	Evaluation of the mannose and galactose content of thyroglobulin demonstrates that intracellular thyroglobulin has more mannose and less galactose than extracellular thyroglobulin; it also shows that TSH decreases the mannose content of thyroglobulin while increasing its galactose content.	Mannose	120-127	thyroglobulin	Rattus norvegicus	97-110
1730219-9	1992	The presence of the oligomannose structures and the mannose-terminating tetrasaccharide on IL-6 may be important in maintaining a high local concentration of the cytokine while limiting its systemic serum level via interaction with soluble mannose-binding serum lectins.	Mannose	25-32	interleukin 6	Homo sapiens	91-95
1547319-0	1992	Evidence for the presence of high-mannose/hybrid oligosaccharide chain(s) on the mouse ZP2 and ZP3.	Mannose	34-41	zona pellucida glycoprotein 2	Mus musculus	87-90
1299347-8	1992	Second, the proportion of mannose-labelled peptides binding to Con A was smaller in the lpr cells.	Mannose	26-33	Fas (TNF receptor superfamily member 6)	Mus musculus	88-91
1547319-0	1992	Evidence for the presence of high-mannose/hybrid oligosaccharide chain(s) on the mouse ZP2 and ZP3.	Mannose	34-41	zona pellucida glycoprotein 3	Mus musculus	95-98
1641515-5	1992	The deflocculating effects of some sugars suggested that mannose may be involved in the mechanism of flocculation, as for strains of the FLO1 phenotypic group.	Mannose	57-64	flocculin FLO1	Saccharomyces cerevisiae S288C	137-141
1419071-7	1992	Mature BMP-2 and propeptide contain high mannose and complex N-linked oligosaccharides, respectively.	Mannose	41-48	bone morphogenetic protein 2	Cricetulus griseus	7-12
1727734-0	1992	Upregulation of GLUT2 mRNA by glucose, mannose, and fructose in isolated rat hepatocytes.	Mannose	39-46	solute carrier family 2 member 2	Rattus norvegicus	16-21
1727734-4	1992	Interestingly, D-mannose and D-fructose could substitute for D-glucose to elevate the GLUT2 mRNA level, whereas 3-O-methyl-D-glucose, 2-deoxy-D-glucose, and sucrose, which were not metabolized or taken up by the cells, were without effect.	Mannose	15-24	solute carrier family 2 member 2	Rattus norvegicus	86-91
1409531-4	1992	In contrast, the promastigotes of L. enriettii were agglutinated by the neoglycoprotein D-mannose-bovine serum albumin (man-BSA).	Mannose	90-97	albumin	Homo sapiens	105-118
1682263-0	1991	Identification of the leukocyte adhesion molecules CD11 and CD18 as receptors for type 1-fimbriated (mannose-specific) Escherichia coli.	Mannose	101-108	integrin subunit beta 2	Homo sapiens	60-64
1929427-4	1991	There was preferential binding of the [35S]TfR to Con A-Sepharose, indicating the existence of a higher density of high mannose chains on the 35S-labeled TfR.	Mannose	120-127	transferrin receptor protein 1	Ovis aries	43-46
1757461-0	1991	Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans.	Mannose	139-146	mannosidase, alpha, class 2A, member 1	Rattus norvegicus	69-89
1757461-1	1991	Golgi alpha-mannosidase II (GlcNAc transferase I-dependent alpha 1,3[alpha 1,6] mannosidase, EC 3.2.1.114) catalyzes the final hydrolytic step in the N-glycan maturation pathway acting as the committed step in the conversion of high mannose to complex type structures.	Mannose	233-240	mannosidase 2, alpha 1	Mus musculus	0-26
1929427-4	1991	There was preferential binding of the [35S]TfR to Con A-Sepharose, indicating the existence of a higher density of high mannose chains on the 35S-labeled TfR.	Mannose	120-127	transferrin receptor protein 1	Ovis aries	154-157
1657953-9	1991	The mutation impairs several steps in the post-translational processing of the insulin receptor:dimerization of 190-kDa proreceptors into a disulfide linked species, proteolytic cleavage of the proreceptor into alpha- and beta-subunits, and terminal processing of the high mannose form of N-linked oligosaccharide into complex carbohydrate.	Mannose	273-280	insulin	Homo sapiens	79-86
1769547-5	1991	Fetuin strongly inhibited the adherence to rabbit intestinal epithelial cells followed by -mannose and D-glucose.	Mannose	91-98	alpha-2-HS-glycoprotein	Oryctolagus cuniculus	0-6
1815506-4	1991	Pulse chase experiments demonstrated that CEA first appears as a 165 kD high mannose precursor which is trimmed to a 160 kD intermediate and finally transformed into the mature 180 kD glycoprotein.	Mannose	77-84	CEA cell adhesion molecule 3	Homo sapiens	42-45
1898081-8	1991	The studies demonstrate that SP-D is a member of the C-type lectin family, and confirm predicted structural similarities to conglutinin, SP-D, and the serum mannose binding proteins.	Mannose	157-164	surfactant protein D	Homo sapiens	29-33
1656972-2	1991	Mannose appeared to specifically inhibit thrombin binding to mouse embryo (ME) and hamster fibroblasts.	Mannose	0-7	coagulation factor II	Mus musculus	41-49
1932126-2	1991	Incubation of the cells at 4 degrees C for 15 min with yeast mannan or with 50 mM mannose, methyl alpha-glucopyranoside, or N-acetylglucosamine caused the concentration of cathepsin D in the culture medium to increase 30-40-fold; mannose-6-phosphate had no effect.	Mannose	82-89	cathepsin D	Rattus norvegicus	172-183
1936188-1	1991	Rhodopsin"s oligosaccharide chains contain predominantly two types of sugar residues: mannose and N-acetylglucosamine.	Mannose	86-93	rhodopsin	Rattus norvegicus	0-9
1717481-6	1991	The first phenotype revealed a sucrase-isomaltase protein that is synthesized as a single chain, mannose-rich polypeptide precursor (pro-SI) and is electrophoretically indistinguishable from pro-SI in normal controls.	Mannose	97-104	sucrase-isomaltase	Homo sapiens	31-49
1918142-3	1991	Kex2 protein is initially synthesized as a prepro-enzyme that undergoes cotranslational signal peptide cleavage and addition of Asn-linked core oligosaccharide and Ser/Thr-linked mannose in the ER.	Mannose	179-186	kexin KEX2	Saccharomyces cerevisiae S288C	0-4
1746915-5	1991	Lectin affinity absorption indicated p102 was mannose containing glycoprotein, isoelectric point (pI) 4.7 and affinity constant of 2.3 x 10(9) M-1, with 5.9 x 10(5) binding sites per cultured human HT-1080 fibrosarcoma cell.	Mannose	46-53	minichromosome maintenance complex component 3	Homo sapiens	37-41
1650361-3	1991	Inhibition of endoplasmic reticulum glucosidase I and II by dNM and its derivatives resulted in an intracellular accumulation of alpha 1-antitrypsin with glucose-containing high mannose type oligosaccharides (precursor).	Mannose	178-185	mannosyl-oligosaccharide glucosidase	Homo sapiens	36-49
1650361-3	1991	Inhibition of endoplasmic reticulum glucosidase I and II by dNM and its derivatives resulted in an intracellular accumulation of alpha 1-antitrypsin with glucose-containing high mannose type oligosaccharides (precursor).	Mannose	178-185	serpin family A member 1	Homo sapiens	129-148
1872811-1	1991	The specificity of human liver lysosomal alpha-mannosidase (EC 3.2.1.24) towards a series of oligosaccharide substrates derived from high-mannose, complex and hybrid asparagine-linked glycans and from the storage products in alpha-mannosidosis was investigated.	Mannose	138-145	mannosidase alpha class 2B member 1	Homo sapiens	31-58
2060023-3	1991	We examined the ability of the monosaccharides fucose (Fuc), galactose (Gal), glucose (Glc), and mannose (Man) to reverse SSF-mediated suppression of NK activity.	Mannose	97-104	peter pan homolog	Homo sapiens	122-125
1767587-3	1991	One group, termed Flo1 phenotype, was inhibited by mannopyranoses and contained all strains bearing known genes affecting flocculation.	Mannose	51-65	flocculin FLO1	Saccharomyces cerevisiae S288C	18-22
1767587-5	1991	Detailed sugar-inhibition work revealed the probable receptor identity of both Flo1 and NewFlo flocculation, as being non-reducing termini of alpha-(1-3)-linked mannan side branches, two or three mannopyranose residues in length.	Mannose	196-209	flocculin FLO1	Saccharomyces cerevisiae S288C	79-83
1906888-1	1991	Previous studies have shown that tissue-type plasminogen activator (t-PA) in blood is cleared by the liver partially through a mannose-specific uptake system.	Mannose	127-134	plasminogen activator, tissue type	Bos taurus	33-66
1906888-1	1991	Previous studies have shown that tissue-type plasminogen activator (t-PA) in blood is cleared by the liver partially through a mannose-specific uptake system.	Mannose	127-134	plasminogen activator, tissue type	Bos taurus	68-72
1922010-4	1991	In this report we demonstrate that 37k Uf contains two N-linked oligosaccharides which are a mixture of complex and high mannose-type oligosaccharides.	Mannose	121-128	acid phosphatase 5, tartrate resistant	Sus scrofa	39-41
1833390-2	1991	Using a standard pulse-chase protocol, we have detected a 52-kDa polypeptide precursor (p52) within the first 5 min of pulse labeling which contains a high mannose-type N-linked oligosaccharide chains.	Mannose	156-163	nuclear factor kappa B subunit 2	Homo sapiens	88-91
1832562-6	1991	Structural analyses of the mannose-trimming intermediates produced by the alpha-mannosidase revealed that specific intermediates were formed during conversion of Man9GlcNAc2-PA to Man5GlcNAc2-PA.	Mannose	27-34	alpha-mannosidase	Ricinus communis	74-91
1820199-6	1991	The results indicate that the alpha 1-6 mannosyltransferase catalyses the addition of mannose to the alpha 1-3 mannose residue, and thus provide additional new evidence to support the revised structure of yeast mannoproteins proposed by Hernandez et al.	Mannose	86-93	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	30-59
1820199-6	1991	The results indicate that the alpha 1-6 mannosyltransferase catalyses the addition of mannose to the alpha 1-3 mannose residue, and thus provide additional new evidence to support the revised structure of yeast mannoproteins proposed by Hernandez et al.	Mannose	111-118	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	30-59
1714453-2	1991	We have isolated the gene from Saccharomyces cerevisiae encoding an alpha-mannosidase of unique specificity which catalyzes the removal of one mannose residue from Man9GlcNAc to produce a single isomer of Man8GlcNAc (Jelinek-Kelly, S., and Herscovics, A.	Mannose	143-150	alpha-mannosidase	Saccharomyces cerevisiae S288C	68-85
1872418-4	1991	In vitro exposure of human and canine SP-A to ozone led to decreases in 1) self-association of SP-A, 2) SP-A-mediated lipid aggregation, and 3) binding of SP-A to immobilized mannose.	Mannose	175-182	surfactant protein A1	Homo sapiens	38-42
1853566-12	1991	Both virion E1 and E2 were found to contain high-mannose, hybrid-type, and complex-type N-glycans.	Mannose	49-56	small nucleolar RNA, H/ACA box 73A	Homo sapiens	12-21
2032800-4	1991	Epithelial explants bound the soluble ligand 125I-mannose bovine serum albumin (BSA) by a mannose-specific process.	Mannose	50-57	albumin	Homo sapiens	65-78
1776950-3	1991	On the contrary, the PII enzyme had a novel substrate specificity that degraded both high-mannose type and hybrid type oligosaccharides derived from ovalbumin, and the core structure of complex type oligosaccharides derived from human transferrin and porcine pancreatic lipase.	Mannose	90-97	transferrin	Homo sapiens	235-246
2052617-10	1991	We conclude that in newborn rat kidney (i) podocalyxin contains both O- and N-linked oligosaccharides [high mannose or hybrid type, biantennary, and complex (sialylated) type], (ii) podocalyxin is sulfated, and (iii) sulfate is located on both O-linked oligosaccharides and on glycopeptides carrying tri- or tetrantennary N-linked structures.	Mannose	108-115	podocalyxin-like	Rattus norvegicus	43-54
1716973-11	1991	Together, these results suggested that comparatively simple oligosaccharide structures of high-mannose type are sufficient for surface expression of the CD22 antigen and for epitope recognition by mAb HD39.	Mannose	95-102	CD22 molecule	Homo sapiens	153-157
2046678-7	1991	Disruption of the HXT1 gene resulted in loss of a portion of high-affinity glucose and mannose transport, and wild-type levels of transport required both the HXT1 and SNF3 genes.	Mannose	87-94	hexose transporter HXT1	Saccharomyces cerevisiae S288C	18-22
2036379-6	1991	In addition, both D-galactose and D-mannose are transported by GLUTs 1-3 at significant rates; furthermore, GLUT 2 is capable of transporting D-fructose.	Mannose	34-43	solute carrier family 2 member 1	Homo sapiens	63-72
2036379-6	1991	In addition, both D-galactose and D-mannose are transported by GLUTs 1-3 at significant rates; furthermore, GLUT 2 is capable of transporting D-fructose.	Mannose	34-43	solute carrier family 2 member 2	Homo sapiens	108-114
1850740-6	1991	The carbohydrate analysis of rhCG showing the presence of 2.1, 3.3, 7.38, 4.2, and 27.8 residues of Fuc, GalNAC, GlcNAC, Gal, and Man, respectively, per mole of the hormone was consistent with the presence of 4 N-linked high mannose type carbohydrate hydrate and 4 O-linked simple carbohydrate chains, probably made up of Gal-GalNAC.	Mannose	225-232	Rh family C glycoprotein	Homo sapiens	29-33
1850740-9	1991	Furthermore, it implies that the alteration from the complex to high mannose type carbohydrates in rhCG does not affect its proper folding.	Mannose	69-76	Rh family C glycoprotein	Homo sapiens	99-103
2061623-6	1991	These results indicate the presence of mannose, glucose (LCH), sialic acid (WGA), and glucosamine (UEA-1, LEA, WGA) on the surface of all cells of the Meg lineage, a variable presence of galactosamine (DBA, SBA, ECA), and a discrepancy in the presence of some galactosamine compounds between platelets and Megs (DBA, SBA).	Mannose	39-46	protein tyrosine phosphatase non-receptor type 4	Homo sapiens	151-154
1901219-2	1991	Analysis of the plasma enzyme indicated that almost all of the large carbohydrate moiety of LCAT (approximately 25% w/w) was N-linked with part of the high-mannose and part of the complex type.	Mannose	156-163	lecithin-cholesterol acyltransferase	Homo sapiens	92-96
1874921-2	1991	These are based on the highly specific interaction between gp120 and the mannose-specific lectins from Narcissus pseudonarcissus (NPL) and Galanthus nivalis (GNL).	Mannose	73-80	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	59-64
2029525-6	1991	Haptoglobin from both normal and diabetic rats was resistant to digestion by endoglycosidase H from Streptomyces griseus, which cleaves high mannose-type chains.	Mannose	141-148	haptoglobin	Rattus norvegicus	0-11
1718301-3	1991	From inhibition studies with aromatic mannose compounds, it was suggested that in contrast to Salmonella strains E. coli strains exhibit a higher hydrophobicity in the binding region adjacent to the CEA-, NCA- and BGP-binding site.	Mannose	38-45	CEA cell adhesion molecule 3	Homo sapiens	199-202
1705959-6	1991	The present results suggest that the rat cortical SP receptor has either a biantennary complex-type or a high mannose-type of carbohydrate chain, and that the carbohydrate chain is implicated in the SP binding activity of the SP receptor system.	Mannose	110-117	tachykinin receptor 1	Rattus norvegicus	50-61
1705959-6	1991	The present results suggest that the rat cortical SP receptor has either a biantennary complex-type or a high mannose-type of carbohydrate chain, and that the carbohydrate chain is implicated in the SP binding activity of the SP receptor system.	Mannose	110-117	tachykinin receptor 1	Rattus norvegicus	226-237
1718301-3	1991	From inhibition studies with aromatic mannose compounds, it was suggested that in contrast to Salmonella strains E. coli strains exhibit a higher hydrophobicity in the binding region adjacent to the CEA-, NCA- and BGP-binding site.	Mannose	38-45	CEA cell adhesion molecule 1	Homo sapiens	214-217
2004464-0	1991	Interference of D-mannose in glucose measurements by glucose oxidase and hexokinase methods.	Mannose	16-25	hexokinase 1	Homo sapiens	73-83
1713644-5	1991	Decreased uptake of the core sugar mannose into -A.FN was similar to that of glucosamine, yet the percent of label in sialic acid was the same as in + A.FN, suggesting a smaller number of oligosaccharide chains per molecule of -A.FN.	Mannose	35-42	fibronectin 1	Rattus norvegicus	51-53
1828321-5	1991	High-mannose and complex (or hybrid)-type moieties were identified on YF NS1 by analysis with endoglycosidases of known specificity.	Mannose	5-12	influenza virus NS1A binding protein	Homo sapiens	73-76
1847387-3	1991	This chimera also contains a modification to prevent high mannose type N-linked glycosylation on kringle 1 of t-PA.	Mannose	58-65	plasminogen activator, tissue type	Homo sapiens	110-114
1714552-8	1991	They correspond to previously identified glycoproteins binding to the plant lectin concanavalin A and binding also to the endogenous mannose-binding lectin CSL and endogenous membrane-bound mannose-binding lectin.	Mannose	133-140	chorionic somatomammotropin hormone like 1	Homo sapiens	156-159
1993651-3	1991	This 171-residue-long collagenous domain separates a short noncollagenous NH2-terminal region of 25 residues from the 155-residue-long globular COOH terminus revealing the structural relation of conglutinin with mannose-binding proteins, pulmonary surfactant-associated proteins, and a complement component C1q.	Mannose	212-219	conglutinin	Bos taurus	195-206
1993651-7	1991	Conglutinin has the greatest sequence similarity with mannose-binding proteins and pulmonary surfactant-associated proteins.	Mannose	54-61	conglutinin	Bos taurus	0-11
1904231-7	1991	The biochemical studies revealed that the removal of the mannose side chain in t-PA significantly reduced its clearance and degradation in isolated perfused livers.	Mannose	57-64	plasminogen activator, tissue type	Homo sapiens	79-83
1672263-2	1991	Virulence factors of recognized importance in the pathogenesis of urinary tract infection (UTI) include adhesins (P fimbriae, certain other mannose-resistant adhesins, and type 1 fimbriae), the aerobactin system, hemolysin, K capsule, and resistance to serum killing.	Mannose	140-147	alpha-1-microglobulin/bikunin precursor	Homo sapiens	91-94
2269302-1	1990	Pulse/chase experiments with [35S]methionine demonstrated that in the control cells, ALP synthesized as a 63-kDa precursor form was rapidly converted to a 66-kDa form, by processing of its N-linked oligosaccharides from the high-mannose type to the complex type, which was expressed on the cell surface after 30 min of chase.	Mannose	229-236	alkaline phosphatase, placental	Homo sapiens	85-88
1979734-5	1990	Using a phenyl-linkage between sugar and Human Serum Albumin (HSA), various mannose-, fucose-, galactose-and glucose-containing neoglycoproteins were synthesized.	Mannose	76-83	albumin	Homo sapiens	47-60
2089039-1	1990	Rat liver mannan-binding protein (R-L-MBP) is a lectin specific for mannose and N-acetylglucosamine.	Mannose	68-75	mannose binding lectin 1	Rattus norvegicus	10-32
2247068-5	1990	Addition of D-mannose or D-fructose, but not D-galactose, in the presence of 5 mM D-glucose suppressed SGLT1 mRNA levels.	Mannose	12-21	solute carrier family 5 member 1	Sus scrofa	103-108
2247068-11	1990	D-Fructose, D-mannose, and to a lesser extent D-galactose all suppressed GLUT-1 mRNA levels.	Mannose	12-21	glucose transport protein	Sus scrofa	73-79
1967020-8	1990	Despite these differences, recombinant beta-hexosaminidase B does serve as a specific substrate for the mannose phosphorylating enzyme, N-acetylglucosaminyl phosphotransferase.	Mannose	104-111	O-GlcNAcase	Homo sapiens	39-58
2171680-7	1990	Recombinant SP-A was purified from the serum-free media of large scale cultures of transfected, amplified CHO cells by affinity chromatography on mannose-Sepharose.	Mannose	146-153	surfactant protein A1	Rattus norvegicus	12-16
2223825-5	1990	[3H]Mannose-labelled transferrin receptor was isolated from NS-1 cells by immunoprecipitation followed by electroelution from SDS polyacrylamide gels.	Mannose	4-11	transferrin	Mus musculus	21-32
2223825-11	1990	Reverse-phase HPLC analysis of tryptic glycopeptides of the isolated [3H]mannose-labelled transferrin receptor gave three 3H-labelled peaks, indicating that all three potential N-glycosylation sites on the receptor are utilised.	Mannose	73-80	transferrin	Mus musculus	90-101
2221912-6	1990	3H-Labeled phosphorylated high mannose-type oligosaccharides isolated from beta-glucuronidase after 1 h of chase were composed primarily of species with one or two phosphodiester groups, but oligosaccharides with one and two phosphomonoesters became the predominant phosphorylated species with longer chase times.	Mannose	31-38	glucuronidase beta	Homo sapiens	75-93
2400992-0	1990	Evidence that high mannose glycopeptides are able to functionally interact with recombinant tumor necrosis factor and recombinant interleukin 1.	Mannose	19-26	tumor necrosis factor	Mus musculus	92-113
2400992-0	1990	Evidence that high mannose glycopeptides are able to functionally interact with recombinant tumor necrosis factor and recombinant interleukin 1.	Mannose	19-26	interleukin 1 complex	Mus musculus	130-143
2400992-11	1990	Conversely, castanosperimine, a glucosidase I inhibitor which blocks the synthesis of mature high mannose structures, inhibits the biological activity of IL-1.	Mannose	98-105	mannosyl-oligosaccharide glucosidase	Mus musculus	32-45
2400992-11	1990	Conversely, castanosperimine, a glucosidase I inhibitor which blocks the synthesis of mature high mannose structures, inhibits the biological activity of IL-1.	Mannose	98-105	interleukin 1 complex	Mus musculus	154-158
2253330-4	1990	LPL is synthesized in the endoplasmic reticulum as an inactive monomer of Mr 51,000; a high-mannose, inactive monomer of Mr 55,500 is then formed.	Mannose	92-99	lipoprotein lipase	Homo sapiens	0-3
2210070-4	1990	CHX-induced inactivation of glucokinase was blocked by the presence of its substrates (glucose and mannose) and an inhibitor (N-acetylglucosamine), all of which also protected against the inhibitory effect of the drug on glucose-induced insulin secretion.	Mannose	99-106	glucokinase	Homo sapiens	28-39
2119296-1	1990	The insulin receptor was immunoprecipitated from cultured human lymphocytes (IM-9) and rat hepatocytes (Fao) after biosynthetic labeling with [3H]glucosamine or [3H]mannose, and the nature of the carbohydrate units was investigated.	Mannose	165-172	insulin receptor	Homo sapiens	4-20
2209754-10	1990	Administration of [3H]galactose resulted in the labeling of rhodopsin both in vivo and in vitro, in part possibly because of its conversion to mannose and subsequent insertion into the core oligosaccharide on the RER.	Mannose	143-150	rhodopsin	Rattus norvegicus	60-69
2079871-7	1990	Mannose and galactosamine contents of apoB were similar in all fractions while contents of both glucosamine and galactose were highest in the least dense fraction.	Mannose	0-7	apolipoprotein B	Rattus norvegicus	38-42
1974897-6	1990	For aminopeptidase N, this arrest was shown to correlate with a reduced ability of its transient high mannose-glycosylated form to form homodimers as judged from cross-linking experiments, suggesting dimerization to be obligatory for transport out of the endoplasmic reticulum.	Mannose	102-109	alanyl aminopeptidase, membrane	Sus scrofa	4-20
2378933-6	1990	Chromatography of the mannoside-eluted peak on wheat germ agglutinin (WGA) indicated the presence of rABP with high mannose- (44%) and hybrid-type (56%) glycans attached.	Mannose	116-123	sex hormone binding globulin	Rattus norvegicus	101-105
2378933-8	1990	Treatment of rABP forms with exoglycosidases confirmed the presence of externally disposed fucose, sialic acid, mannose, and galactose residues.	Mannose	112-119	sex hormone binding globulin	Rattus norvegicus	13-17
2385230-8	1990	The nonadditivity of sequential treatments with the two exoglycosidases suggests, a heterogeneous population of A2AR containing either complex- or high mannose-type carbohydrate chains.	Mannose	152-159	adenosine A2a receptor	Homo sapiens	112-116
2385230-9	1990	These data suggest the A2AR is a Mr 45,000 glycoprotein with a single carbohydrate chain of either the complex or high mannose type.	Mannose	119-126	adenosine A2a receptor	Homo sapiens	23-27
2141816-2	1990	Here, we determined the in vitro and in vivo bioactivity of recombinant FSH produced by CHO mutant cells deficient in the glycosylation enzyme N-acetylglucosamine transferase-I (NAGT-), resulting in glycoproteins with asparagine-linked (GlcNAc)2(Mannose)5 oligosaccharides, or mutant cells defective in sialic acid transport into the Golgi (ST-).	Mannose	246-253	solute carrier family 5 member 1	Homo sapiens	178-182
1846339-7	1991	The mannose-dependent interaction of SP-A particles with macrophages is not due to the mannose-specific receptor on the cell surface of macrophages as shown in experiments with macrophages exhibiting reduced mannose receptor activity.	Mannose	4-11	surfactant protein A1	Rattus norvegicus	37-41
1673444-2	1991	Glucose, mannose, and 2-deoxyglucose are good substrates of glucokinase which are easily taken up into B-cells.	Mannose	9-16	hexokinase-4	Ictalurus punctatus	60-71
1673444-3	1991	Glucose and mannose are well-known stimuli of insulin release in mammals and fish.	Mannose	12-19	insulin	Homo sapiens	46-53
1824724-0	1991	Molecular cloning and expression of cDNA encoding the enzyme that controls conversion of high-mannose to hybrid and complex N-glycans: UDP-N-acetylglucosamine: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.	Mannose	94-101	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Oryctolagus cuniculus	135-222
2205700-9	1990	Treatment of immunoprecipitated labeled LPL with endoglycosidase H showed that the oligosaccharide chains on her enzyme were of the high-mannose type and not processed as in controls.	Mannose	137-144	lipoprotein lipase	Homo sapiens	40-43
2114451-7	1990	The present evidence for differential effects on intracellular tyrosinase transfer and melanization by different stages of carbohydrate processing inhibition suggests that asparagine-linked oligosaccharides, relating to the first mannose-trimming stages, determine the function of tyrosinase transfer as well as melanization through a specific intracellular recognition process in pigment cells.	Mannose	230-237	tyrosinase	Mus musculus	63-73
1972431-1	1990	Cerebrospinal fluid samples from 239 patients with various neurological disorders were tested for the presence of autoantibodies to an endogenous mannose-binding protein, the cerebellar soluble lectin CSL, by means of an immunoblotting test with rat CSL as antigen.	Mannose	146-153	recombination signal binding protein for immunoglobulin kappa J region	Homo sapiens	201-204
2141203-3	1990	By pulse-chase labeling experiments in the presence of drugs which inhibit N-linked oligosaccharide addition and processing we demonstrate that addition of high mannose precursor oligosaccharides is necessary for transport and cleavage of the viral GP-C glycoprotein.	Mannose	161-168	glycophorin C (Gerbich blood group)	Homo sapiens	249-253
2157473-2	1990	Rat bone marrow-derived macrophages internalized 75% of [125I]myeloperoxidase through a mannose-specific process.	Mannose	88-95	myeloperoxidase	Rattus norvegicus	62-77
1692546-3	1990	Colonic sucrase-isomaltase was purified by immunoprecipitation with selected monoclonal antibodies and identified predominantly as high-mannose and complex glycosylated single-chain precursors endowed with relatively low levels of enzyme activities.	Mannose	136-143	sucrase-isomaltase	Homo sapiens	8-26
2161534-3	1990	In these cells, the EPO-R is synthesized as a minor 62-kDa unglycosylated form and a major 64-kDa form carrying one high-mannose N-linked oligosaccharide.	Mannose	121-128	erythropoietin	Mus musculus	20-23
2158279-4	1990	The oligosaccharide chains of the glycoprotein can be released by treatment with endoglycosidase H, suggesting that gp46 has high-mannose type of glycans.	Mannose	130-137	serpin family H member 1	Rattus norvegicus	116-120
2373515-5	1990	Immunoprecipitation from Chinese hamster ovary cells expressing transfected MCP cDNA showed that E4.3 detects both the mature 66,000 higher MW form of MCP and its 48,000 MW pro-MCP precursor, which lacks O-linked carbohydrate and bears only simple high-mannose-type N-linked carbohydrate.	Mannose	253-260	CD46 molecule	Homo sapiens	151-154
2373515-5	1990	Immunoprecipitation from Chinese hamster ovary cells expressing transfected MCP cDNA showed that E4.3 detects both the mature 66,000 higher MW form of MCP and its 48,000 MW pro-MCP precursor, which lacks O-linked carbohydrate and bears only simple high-mannose-type N-linked carbohydrate.	Mannose	253-260	CD46 molecule	Homo sapiens	151-154
1970823-1	1990	Thy-1 and a number of other proteins are anchored to the outer hemi-leaflet of membranes by a glycolipid moiety containing ethanolamine phosphate, mannose, glucosamine, and phosphatidylinositol.	Mannose	147-154	thymus cell antigen 1, theta	Mus musculus	0-5
1969394-8	1990	These findings indicate that highly purified intestinal mucins possess specific mannosyl receptor sites for bacterial type 1 pili on E. coli CL-49, but that strong hydrophobic interactions between the mucin and the pili stabilize the mannose-dependent binding process.	Mannose	234-241	solute carrier family 13 member 2	Rattus norvegicus	56-61
1367433-6	1990	We found that with one exception, all mutant activators lack the high mannose glycan found at asn 117 of native t-PA.	Mannose	70-77	plasminogen activator, tissue	Mus musculus	112-116
1965946-1	1990	The macrophage mannose receptor (MMR) facilitates the binding and internalization of microorganisms and glycoproteins with terminal mannose residues.	Mannose	15-22	ATPase, class II, type 9B	Mus musculus	33-36
2140264-5	1990	It is calculated that, in addition to the phosphatidylinositol-glycan anchor structure, ecto-5"-nucleotidase of human chorionic cells should carry 4 oligosaccharide side chains per subunit, 3 of which should be of the complex and one of the high mannose type.	Mannose	246-253	5'-nucleotidase ecto	Homo sapiens	88-108
1969394-9	1990	We speculate that the mucin receptors for type 1 pili reside in oligosaccharides of the 118-kilodalton "link" glycopeptide, since this is the only mucin component known to contain mannose.	Mannose	180-187	solute carrier family 13 member 2	Rattus norvegicus	22-27
1972880-1	1990	The close connection between mannose-resistant hemagglutination (MRHA) and adhesion to uroepithelial cells of urinary E. coli with regard to the pathogenesis of urinary tract infection (UTI) prompted us to examine the hemagglutinating ability of 1499 E. coli strains from urine using human blood group OP1 erythrocytes.	Mannose	29-36	bone morphogenetic protein 7	Homo sapiens	302-305
2158304-20	1990	(3) The observation that mannose, inositol monophosphate and glucosamine block the action of insulin of on lipogenesis supports a role of mannose- and glucosamine-containing IP-oligosaccharides as second messengers for this insulin effect.	Mannose	25-32	insulin	Homo sapiens	93-100
2157039-3	1990	Consistent with endoplasmic reticulum and nuclear membrane localization, the bulk of gp110 was sensitive to endoglycosidase H, indicating high-mannose, pre-Golgi, N-linked glycosylation; while consistent with Golgi and plasma membrane localization, gp350/220 was mostly resistant to endoglycosidase H because of complex N- and O-linked glycosylation.	Mannose	143-150	CD68 molecule	Homo sapiens	85-90
2307676-4	1990	The distribution of LPL within the endoplasmic reticulum (ER) and Golgi/post-Golgi secretory pathway was assessed by differentiating between LPL high mannose and complex forms.	Mannose	150-157	lipoprotein lipase	Rattus norvegicus	20-23
2307676-5	1990	After fasting, the majority of LPL is in the high mannose ER form (65%, 0.97 micrograms/g wet weight tissue), whereas the LPL complex form comprises only 35% (or 0.52 micrograms/g).	Mannose	50-57	lipoprotein lipase	Rattus norvegicus	31-34
2307676-7	1990	Kinetic analysis suggests that high mannose LPL disappears with a half-life of t0.5 = 40 min in both fed and fasted rats, indicating that the redistribution of LPL mass during feeding/fasting does not arise by differential retention within ER.	Mannose	36-43	lipoprotein lipase	Rattus norvegicus	44-47
2318210-12	1990	The constituent monosaccharides of the carbohydrate structures of rCD4 were found to be fucose, mannose, galactose, N-acetylglucosamine and N-acetylneuraminic acid.	Mannose	96-103	Cd4 molecule	Rattus norvegicus	66-70
2318210-14	1990	The tryptic map of rCD4 treated with endo-beta-N-acetylglucosamine H demonstrated that only complex-type oligosaccharides are attached to Asn-271, while Asn-300 has high-mannose or hybrid structures attached in addition to complex-type oligosaccharides.	Mannose	170-177	Cd4 molecule	Rattus norvegicus	19-23
2187500-4	1990	Digestion of the purified gp120 and gp160 with endoglycosidases revealed that both proteins are heavily glycosylated and contain complex carbohydrates, in contrast to the intracellular form of gp160 which has been shown to contain mannose-rich immature sugars.	Mannose	231-238	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	26-31
2158304-0	1990	Mannose, glucosamine and inositol monophosphate inhibit the effects of insulin on lipogenesis.	Mannose	0-7	insulin	Homo sapiens	71-78
2158304-15	1990	We also found that the effect of insulin on lipogenesis was blocked by mannose, glucosamine and inositol monophosphate, whereas the insulin effects on 3-O-methylglucose, cyclic AMP and lipolysis were unaffected.	Mannose	71-78	insulin	Homo sapiens	33-40
2158304-20	1990	(3) The observation that mannose, inositol monophosphate and glucosamine block the action of insulin of on lipogenesis supports a role of mannose- and glucosamine-containing IP-oligosaccharides as second messengers for this insulin effect.	Mannose	25-32	insulin	Homo sapiens	224-231
2158304-20	1990	(3) The observation that mannose, inositol monophosphate and glucosamine block the action of insulin of on lipogenesis supports a role of mannose- and glucosamine-containing IP-oligosaccharides as second messengers for this insulin effect.	Mannose	138-145	insulin	Homo sapiens	93-100
2298734-1	1990	Serum mannan-binding protein (S-MBP), a lectin specific for mannose and N-acetylglucosamine, was documented to activate complement through the classical pathway.	Mannose	60-67	transmembrane 9 superfamily member 3	Homo sapiens	30-35
1968615-10	1990	The remaining single oligosaccharide side chain released from the mutant arylsulfatase-A by pronase digestion was normally processed to complex and high-mannose forms.	Mannose	153-160	arylsulfatase A	Homo sapiens	73-88
2111144-4	1990	Two molecular forms of alpha 1-antitrypsin could be identified: a 51-kDa intracellular form, susceptible to endoglucosaminidase H, thus representing the high-mannose type precursor form and a 56-kDa form resistant to endoglucosaminidase H which was secreted into the medium.	Mannose	158-165	serpin family A member 1	Homo sapiens	23-42
2138626-2	1990	The Chinese hamster ovary (CHO) mutant cell line Lec1 is deficient in this enzyme activity and, therefore, accumulates mannose-terminating cell surface ASN-linked oligosaccharides.	Mannose	119-126	adhesion G protein-coupled receptor L2	Homo sapiens	49-53
2138626-3	1990	Consequently, Lec1 cells are sensitive to the cytotoxic effects of the mannose-binding lectin Concanavalin A (Con A).	Mannose	71-78	adhesion G protein-coupled receptor L2	Homo sapiens	14-18
2406237-5	1990	Evidence is presented that gp160 is subject to mannose trimming in the Golgi complex, which is inhibited by 1-deoxymannojirimycin (a specific Golgi alpha-mannosidase I inhibitor).	Mannose	47-54	glutamyl aminopeptidase	Homo sapiens	27-32
2183815-4	1990	Analytical studies suggest that the antibodies are directed against the mannose residues of the HIV-1 glycoprotein (gp) 120 and its precursor gp 160.	Mannose	72-79	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	142-148
2095335-7	1990	Likewise, mannose inhibited both alpha- and beta-man activities equally.	Mannose	10-17	mannosidase beta	Homo sapiens	44-52
2105725-3	1990	Analysis of oligosaccharide units suggested that rat cathepsin E possesses one N-linked carbohydrate unit, probably of the high mannose type.	Mannose	128-135	cathepsin E	Rattus norvegicus	53-64
1690645-2	1990	By lectin affinity immunoelectrophoresis, PAPP-A contained sialic acid, glucose/mannose and N-acetyl-alpha-D-galactosamine.	Mannose	80-87	pappalysin 1	Homo sapiens	42-48
29277605-3	2018	With ATP (Km=104.7muM) as phosphate donor, hexokinase catalyzes the phosphorylation of glucose (Km=24.9muM) and mannose (Km=8.8muM).	Mannose	112-119	latexin	Homo sapiens	18-21
2322386-11	1990	RP2 was shown to be a glycoprotein containing mannose and galactose residues.	Mannose	46-53	RP2 activator of ARL3 GTPase	Rattus norvegicus	0-3
32797887-2	2020	In this work, the mannose was grafted onto the bovine serum albumin (BSA) encapsulated Au NCs (BSA-Au NCs) to produce a mannose functionalized BSA-Au NCs (Man-BSA-Au NCs) as a new fluorescence probe for Concanavalin A (Con A) detection and human breast cancer cell imaging.	Mannose	18-25	albumin	Homo sapiens	54-67
32797887-2	2020	In this work, the mannose was grafted onto the bovine serum albumin (BSA) encapsulated Au NCs (BSA-Au NCs) to produce a mannose functionalized BSA-Au NCs (Man-BSA-Au NCs) as a new fluorescence probe for Concanavalin A (Con A) detection and human breast cancer cell imaging.	Mannose	120-127	albumin	Homo sapiens	54-67
1688937-5	1990	Deglycosylation of LAMP indicates that it contains N-linked high mannose or hybrid sugars and a minor amount of sialic acid.	Mannose	65-72	limbic system associated membrane protein	Homo sapiens	19-23
2104682-5	1990	The mutant gp160 contained N-linked oligosaccharide chains with mannose-rich cores similar to those of the gp160 produced by the wild-type clone.	Mannose	64-71	glutamyl aminopeptidase	Homo sapiens	11-16
33973684-5	2021	Cycloheximide chase assays together with treatment by protein degradation and mannose trimming inhibitors demonstrated that the defect in NKCC2 maturation arise from ER retention and associated degradation (ERAD).	Mannose	78-85	solute carrier family 12 member 1	Homo sapiens	138-143
33798575-2	2021	UP1-1 mainly composed of galactose, mannose and glucose in a molar ratio of 0.8:1.0:4.6 with an average molecular weight of 281 kDa.	Mannose	36-43	major urinary protein 1	Mus musculus	0-5
33776987-9	2020	Analysis of epitope sugars on TLA indicated a high abundance of mannose, fucose, N-acetylglucosamine, and N-acetylgalactosamine.	Mannose	64-71	histocompatibility 2, T region locus 18	Mus musculus	30-33
32796567-3	2020	APCs express mannose receptors on their surface to recognize pathogen specifically and promote cross-presentation of antigen.	Mannose	13-20	amyloid P component, serum	Mus musculus	0-4
29277605-3	2018	With ATP (Km=104.7muM) as phosphate donor, hexokinase catalyzes the phosphorylation of glucose (Km=24.9muM) and mannose (Km=8.8muM).	Mannose	112-119	hexokinase 1	Homo sapiens	43-53
29277605-4	2018	With respect to glucose, mannose and inorganic pyrophosphate respectively are a competitive, and a mixed inhibitor of hexokinase.	Mannose	25-32	hexokinase 1	Homo sapiens	118-128
19723356-0	2010	Immune responses to polyethylenimine-mannose-delivered plasmid DNA encoding a Fasciola gigantica fatty acid binding protein in mice.	Mannose	37-44	glutamatic-oxaloacetic transaminase 2, mitochondrial	Mus musculus	97-123
34891122-7	2022	Our accumulated evidence obtained from scientific databases particularly PubMed and Google Scholar databases indicate that mannose-specific/mannose-binding lectins (MBL) have potent efficacies like anti-infectivity, complement cascade induction, immunoadjuvants, DC-SIGN antagonists, or glycomimetic approach, which can prove useful in the strategy of COVID-19 combat along with the glycobiological aspects of SARS-CoV-2 infections and antiviral immunity.	Mannose	123-130	mannose binding lectin 2	Homo sapiens	165-168
19723356-7	2010	Gene delivery using polyethylenimine-mannose ligand showed significant expression of IFN-gamma and TNF (P &lt; 0.05), but no significant difference in IL-2, IL-4 and IL-5 (P&gt;0.05) cytokine expression was observed between naked-DNA- and mannosylated PEI-DNA-delivered mice.	Mannose	37-44	interferon gamma	Mus musculus	85-94
19723356-7	2010	Gene delivery using polyethylenimine-mannose ligand showed significant expression of IFN-gamma and TNF (P &lt; 0.05), but no significant difference in IL-2, IL-4 and IL-5 (P&gt;0.05) cytokine expression was observed between naked-DNA- and mannosylated PEI-DNA-delivered mice.	Mannose	37-44	tumor necrosis factor	Mus musculus	99-102
28528272-8	2017	The carbohydrates on legumain were shown to be of the hybrid or high mannose type, whereas cystatin E/M was characterized as complex mannose-linked.	Mannose	133-140	cystatin E/M	Homo sapiens	91-101
34891122-7	2022	Our accumulated evidence obtained from scientific databases particularly PubMed and Google Scholar databases indicate that mannose-specific/mannose-binding lectins (MBL) have potent efficacies like anti-infectivity, complement cascade induction, immunoadjuvants, DC-SIGN antagonists, or glycomimetic approach, which can prove useful in the strategy of COVID-19 combat along with the glycobiological aspects of SARS-CoV-2 infections and antiviral immunity.	Mannose	140-147	mannose binding lectin 2	Homo sapiens	165-168
34814011-5	2022	Importantly, D-m treatment prevented relapses in a relapsing-remitting model of EAE, which mimics the most common clinical manifestation of MS. EAE suppression was accompanied by increased frequency of CD4+FoxP3+ Tregs in the central nervous system, suggesting that EAE suppression resulted from Treg cell induction by D-m.	Mannose	319-322	CD4 antigen	Mus musculus	202-205
34662214-5	2022	Here, we utilize N-glycan profiling by nanoLC-chip QTOF mass cytometry to characterize the bacterial neuraminidase-associated compositional shift of the macrophage glycocalyx, which revealed a decrease in sialylated and an increase in fucosylated and high mannose structures.	Mannose	256-263	neuraminidase 1	Homo sapiens	101-114
34716931-5	2022	Thus far, polymorphisms in Fc gamma receptors (FcgammaRs), Mannose Binding Lectin (MBL), Dectin-2, Toll-like Receptors (TLRs) and macrophage colony stimulating factor (M-CSF) have been associated with susceptibility to cryptococcal disease.	Mannose	59-66	mannose binding lectin 2	Homo sapiens	83-86
34814011-5	2022	Importantly, D-m treatment prevented relapses in a relapsing-remitting model of EAE, which mimics the most common clinical manifestation of MS. EAE suppression was accompanied by increased frequency of CD4+FoxP3+ Tregs in the central nervous system, suggesting that EAE suppression resulted from Treg cell induction by D-m.	Mannose	319-322	forkhead box P3	Mus musculus	206-211
34965437-3	2021	Using a genetic approach in yeast cells, we establish that one remodeling event, the removal of ethanolamine-phosphate from mannose 2 via Ted1p (yPGAP5), is essential for cell viability in the absence of the Golgi-localized putative phosphodiesterase Dcr2p.	Mannose	124-131	Ted1p	Saccharomyces cerevisiae S288C	138-143
34873736-2	2022	They were composed of different monosaccharides and the content of monosaccharides varied significantly while DLP-1 (Mw 1.38 x 106  Da) was mainly composed of mannose (71.69%) and glucose (22.89%), and DLP-2 (Mw 1.93 x 106  Da) was constituted by rhamnose (35.05%), arabinose (24.12%), and galactose (25.65%).	Mannose	159-166	prenyl (solanesyl) diphosphate synthase, subunit 2	Mus musculus	110-115
34875536-1	2022	INTRODUCTION: Lysosome-associated membrane glycoprotein 2 (LAMP-2) is a target protein for glycosylation by N-acetylglucosaminyltransferase IV (GnT-IV), which catalyzes the formation of beta1,4GlcNAc branches on the mannose core of N-glycans in choriocarcinoma cells.	Mannose	216-223	lysosomal associated membrane protein 2	Homo sapiens	14-57
34875536-1	2022	INTRODUCTION: Lysosome-associated membrane glycoprotein 2 (LAMP-2) is a target protein for glycosylation by N-acetylglucosaminyltransferase IV (GnT-IV), which catalyzes the formation of beta1,4GlcNAc branches on the mannose core of N-glycans in choriocarcinoma cells.	Mannose	216-223	lysosomal associated membrane protein 2	Homo sapiens	59-65
34875536-1	2022	INTRODUCTION: Lysosome-associated membrane glycoprotein 2 (LAMP-2) is a target protein for glycosylation by N-acetylglucosaminyltransferase IV (GnT-IV), which catalyzes the formation of beta1,4GlcNAc branches on the mannose core of N-glycans in choriocarcinoma cells.	Mannose	216-223	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A	Homo sapiens	144-150
34952645-3	2021	DC-SIGN binds variously crosslinked mannose-rich and fucosylated glycans and lipomannans that are expressed by helminth, protist, fungal, bacterial and viral pathogens including three of the most life-threatening fungi, Aspergillus fumigatus, Candida albicans and Cryptococcus neoformans.	Mannose	36-43	CD209a antigen	Mus musculus	0-7
34800594-1	2022	BACKGROUND: High mannose has previously associated with insulin resistance and cardiovascular disease (CVD).	Mannose	17-24	insulin	Homo sapiens	56-63
34962630-1	2022	Technetium-99m-labeled Tilmanocept or Lymphoseek  (Cardinal Health, Dublin, Ohio) is a soluble, synthetic molecule with a small diameter (7 nm), which is comprised of technetium-99m chelated to a dextran backbone containing multiple units of mannose ligands with a high affinity for CD206, a receptor located on the surface of macrophages and dendritic cells that are found in high concentration in lymph nodes.	Mannose	242-249	mannose receptor C-type 1	Homo sapiens	283-288
34962630-3	2022	The binding of mannose ligand and CD206 results in the internalization of the ligand and receptor into the cell.	Mannose	15-22	mannose receptor C-type 1	Homo sapiens	34-39
34886901-0	2021	ZIP10 is a negative determinant for anti-tumor effect of mannose in thyroid cancer by activating phosphate mannose isomerase.	Mannose	57-64	solute carrier family 39 (zinc transporter), member 10	Mus musculus	0-5
34944979-0	2021	D-Mannose Slows Glioma Growth by Modulating Myeloperoxidase Activity.	Mannose	0-9	myeloperoxidase	Mus musculus	44-59
34944979-4	2021	As expected, we found that D-mannose treatment decreased the number of MPO+ cells and slowed glioma progression compared to PBS-treated control animals with gliomas.	Mannose	27-36	myeloperoxidase	Mus musculus	71-74
34944979-5	2021	Unexpectedly, instead of decreasing MPO activity, D-mannose increased MPO activity in vivo, revealing that D-mannose boosted the MPO activity per MPO+ cell.	Mannose	50-59	myeloperoxidase	Mus musculus	70-73
34944979-5	2021	Unexpectedly, instead of decreasing MPO activity, D-mannose increased MPO activity in vivo, revealing that D-mannose boosted the MPO activity per MPO+ cell.	Mannose	50-59	myeloperoxidase	Mus musculus	129-132
34944979-5	2021	Unexpectedly, instead of decreasing MPO activity, D-mannose increased MPO activity in vivo, revealing that D-mannose boosted the MPO activity per MPO+ cell.	Mannose	50-59	myeloperoxidase	Mus musculus	146-149
34944979-5	2021	Unexpectedly, instead of decreasing MPO activity, D-mannose increased MPO activity in vivo, revealing that D-mannose boosted the MPO activity per MPO+ cell.	Mannose	107-116	myeloperoxidase	Mus musculus	36-39
34944979-5	2021	Unexpectedly, instead of decreasing MPO activity, D-mannose increased MPO activity in vivo, revealing that D-mannose boosted the MPO activity per MPO+ cell.	Mannose	107-116	myeloperoxidase	Mus musculus	70-73
34944979-5	2021	Unexpectedly, instead of decreasing MPO activity, D-mannose increased MPO activity in vivo, revealing that D-mannose boosted the MPO activity per MPO+ cell.	Mannose	107-116	myeloperoxidase	Mus musculus	129-132
34944979-5	2021	Unexpectedly, instead of decreasing MPO activity, D-mannose increased MPO activity in vivo, revealing that D-mannose boosted the MPO activity per MPO+ cell.	Mannose	107-116	myeloperoxidase	Mus musculus	146-149
34944979-8	2021	We found that D-mannose modulated MPO activity via two mechanisms: directly via N-glycosylation of MPO, which boosted the MPO activity of each molecule, and indirectly by increasing H2O2 production, the main substrate for MPO.	Mannose	14-23	myeloperoxidase	Mus musculus	34-37
34944979-8	2021	We found that D-mannose modulated MPO activity via two mechanisms: directly via N-glycosylation of MPO, which boosted the MPO activity of each molecule, and indirectly by increasing H2O2 production, the main substrate for MPO.	Mannose	14-23	myeloperoxidase	Mus musculus	99-102
34944979-8	2021	We found that D-mannose modulated MPO activity via two mechanisms: directly via N-glycosylation of MPO, which boosted the MPO activity of each molecule, and indirectly by increasing H2O2 production, the main substrate for MPO.	Mannose	14-23	myeloperoxidase	Mus musculus	122-125
34944979-8	2021	We found that D-mannose modulated MPO activity via two mechanisms: directly via N-glycosylation of MPO, which boosted the MPO activity of each molecule, and indirectly by increasing H2O2 production, the main substrate for MPO.	Mannose	14-23	myeloperoxidase	Mus musculus	222-225
34944979-9	2021	This increased host immune response acted to reduce tumor size, suggesting that increasing MPO activity such as through D-mannose administration may be a potential new therapeutic direction for glioma treatment.	Mannose	120-129	myeloperoxidase	Mus musculus	91-94
34886901-8	2021	Further studies found that the expression of zinc transport protein ZIP10, which transport Zn2+ from extracellular area into cells, was negatively related to the response of thyroid cancer cells to mannose.	Mannose	198-205	solute carrier family 39 (zinc transporter), member 10	Mus musculus	68-73
34886901-10	2021	Moreover, ectopic expression of ZIP10 in mannose-sensitive cells decrease their cellular response to mannose.	Mannose	41-48	solute carrier family 39 (zinc transporter), member 10	Mus musculus	32-37
34886901-10	2021	Moreover, ectopic expression of ZIP10 in mannose-sensitive cells decrease their cellular response to mannose.	Mannose	101-108	solute carrier family 39 (zinc transporter), member 10	Mus musculus	32-37
34886901-11	2021	Mechanistically, mannose exerted its anti-tumor effect by inhibiting cellular glycolysis; however, this effect was highly dependent on expression status of ZIP10.	Mannose	17-24	solute carrier family 39 (zinc transporter), member 10	Mus musculus	156-161
34482605-8	2021	Although BSC2-overexpression increased the level of mannose in the cell wall, DPM1-overexpression in both BY4741 and bsc2  could confer resistance to CAS and AMB.	Mannose	52-59	Bsc2p	Saccharomyces cerevisiae S288C	9-13
34496641-10	2021	Both inhibitors displayed the highest upregulation of the inflammatory chemokine Ccl5, the most downregulated gene was the one for mannose receptors Mrc1.	Mannose	131-138	C-C motif chemokine ligand 5	Homo sapiens	81-85
34496641-10	2021	Both inhibitors displayed the highest upregulation of the inflammatory chemokine Ccl5, the most downregulated gene was the one for mannose receptors Mrc1.	Mannose	131-138	mannose receptor C-type 1	Homo sapiens	149-153
34533861-5	2021	Leukemia cells express high levels of phosphomannose isomerase (PMI), which mobilizes mannose to glycolysis; consequently, even mannose in the blood can be used as an energy source for glycolysis.	Mannose	86-93	mannose phosphate isomerase	Homo sapiens	38-62
34533861-5	2021	Leukemia cells express high levels of phosphomannose isomerase (PMI), which mobilizes mannose to glycolysis; consequently, even mannose in the blood can be used as an energy source for glycolysis.	Mannose	86-93	mannose phosphate isomerase	Homo sapiens	64-67
34533861-5	2021	Leukemia cells express high levels of phosphomannose isomerase (PMI), which mobilizes mannose to glycolysis; consequently, even mannose in the blood can be used as an energy source for glycolysis.	Mannose	128-135	mannose phosphate isomerase	Homo sapiens	38-62
34533861-5	2021	Leukemia cells express high levels of phosphomannose isomerase (PMI), which mobilizes mannose to glycolysis; consequently, even mannose in the blood can be used as an energy source for glycolysis.	Mannose	128-135	mannose phosphate isomerase	Homo sapiens	64-67
34533861-6	2021	Conversely, suppression of PMI expression or a mannose load exceeding the processing capacity of PMI inhibited transcription of genes related to mitochondrial metabolism and TCA cycle, thus suppressing the growth of leukemia cells.	Mannose	47-54	mannose phosphate isomerase	Homo sapiens	97-100
33779504-7	2021	Gene profiling expression analysis suggested that Gal-3 deletion resulted in differentially modulated expression of the genes encoding beta-glucan, mannose and chitin-responsive pattern recognition receptors, signal transduction, inflammation, and phagocytosis.	Mannose	148-155	lectin, galactose binding, soluble 3	Mus musculus	50-55
34695439-2	2021	B3GLCT mediates modification of proteins with thrombospondin type I repeats (TSR) that contain O-linked glucose beta1-3 fucose and C-linked mannose glycosylation motifs.	Mannose	140-147	beta 3-glucosyltransferase	Homo sapiens	0-6
34749758-8	2021	In addition, we found that D-mannose increased the expression of OT and OTR through polarization of macrophages to the M2 type.	Mannose	27-36	oxytocin receptor	Homo sapiens	72-75
34634664-3	2021	The core of the vaccine platform is the copolymer p(Man-TLR7), composed of monomers with pendant mannose or a toll-like receptor 7 (TLR7) agonist.	Mannose	97-104	toll like receptor 7	Homo sapiens	56-60
34702739-5	2021	Multiagent molecular MRI performed to assess oxidative stress (targeting myeloperoxidase (MPO) using MPO-bis-5-hydroxytryptamide diethylenetriaminepentaacetate gadolinium (Gd)) and phagocytosis (using cross-linked iron oxide (CLIO) nanoparticles) in vivo revealed that d-mannose-treated mice had smaller total MPO-Gd+ areas than those of PBS-control mice, consistent with decreased MPO-mediated oxidative stress.	Mannose	269-278	myeloperoxidase	Mus musculus	73-88
34702739-5	2021	Multiagent molecular MRI performed to assess oxidative stress (targeting myeloperoxidase (MPO) using MPO-bis-5-hydroxytryptamide diethylenetriaminepentaacetate gadolinium (Gd)) and phagocytosis (using cross-linked iron oxide (CLIO) nanoparticles) in vivo revealed that d-mannose-treated mice had smaller total MPO-Gd+ areas than those of PBS-control mice, consistent with decreased MPO-mediated oxidative stress.	Mannose	269-278	myeloperoxidase	Mus musculus	90-93
34702739-5	2021	Multiagent molecular MRI performed to assess oxidative stress (targeting myeloperoxidase (MPO) using MPO-bis-5-hydroxytryptamide diethylenetriaminepentaacetate gadolinium (Gd)) and phagocytosis (using cross-linked iron oxide (CLIO) nanoparticles) in vivo revealed that d-mannose-treated mice had smaller total MPO-Gd+ areas than those of PBS-control mice, consistent with decreased MPO-mediated oxidative stress.	Mannose	269-278	myeloperoxidase	Mus musculus	101-104
34702739-5	2021	Multiagent molecular MRI performed to assess oxidative stress (targeting myeloperoxidase (MPO) using MPO-bis-5-hydroxytryptamide diethylenetriaminepentaacetate gadolinium (Gd)) and phagocytosis (using cross-linked iron oxide (CLIO) nanoparticles) in vivo revealed that d-mannose-treated mice had smaller total MPO-Gd+ areas than those of PBS-control mice, consistent with decreased MPO-mediated oxidative stress.	Mannose	269-278	myeloperoxidase	Mus musculus	310-313
34702739-5	2021	Multiagent molecular MRI performed to assess oxidative stress (targeting myeloperoxidase (MPO) using MPO-bis-5-hydroxytryptamide diethylenetriaminepentaacetate gadolinium (Gd)) and phagocytosis (using cross-linked iron oxide (CLIO) nanoparticles) in vivo revealed that d-mannose-treated mice had smaller total MPO-Gd+ areas than those of PBS-control mice, consistent with decreased MPO-mediated oxidative stress.	Mannose	269-278	myeloperoxidase	Mus musculus	382-385
34634664-4	2021	Thus, p(Man-TLR7) is designed to target relevant antigen-presenting cells (APCs) via mannose-binding receptors and then activate TLR7 upon endocytosis.	Mannose	85-92	toll like receptor 7	Homo sapiens	12-16
34652144-5	2021	In this study, we report on the discovery of a new class of potent glycomimetic DC-SIGN antagonists from a focused library of triazole-based mannose analogues.	Mannose	141-148	CD209 molecule	Homo sapiens	80-87
34561933-0	2021	D-mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF-2alpha-dependent manner.	Mannose	0-9	endothelial PAS domain protein 1	Mus musculus	91-101
34561933-4	2021	Combined with Epas1 gene gain- and loss-of-function, histology, immunofluorescence, quantitative RT-PCR, Western blot, cell viability and flow cytometry experiments were performed to evaluate the chondroprotective effects of D-mannose in OA progression and the role of hypoxia-inducible factor 2 alpha (HIF-2 alpha) in D-mannose-induced ferroptosis resistance of chondrocytes.	Mannose	319-328	endothelial PAS domain protein 1	Mus musculus	303-314
34561933-6	2021	HIF-2alpha was identified as a central mediator in D-mannose-induced ferroptosis resistance of chondrocytes.	Mannose	51-60	endothelial PAS domain protein 1	Mus musculus	0-10
34561933-7	2021	Furthermore, overexpression of HIF-2alpha in chondrocytes by Ad-Epas1 intra-articular injection abolished the chondroprotective effect of D-mannose during OA progression and eliminated the role of D-mannose as a ferroptosis suppressor.	Mannose	138-147	endothelial PAS domain protein 1	Mus musculus	31-41
34561933-7	2021	Furthermore, overexpression of HIF-2alpha in chondrocytes by Ad-Epas1 intra-articular injection abolished the chondroprotective effect of D-mannose during OA progression and eliminated the role of D-mannose as a ferroptosis suppressor.	Mannose	138-147	endothelial PAS domain protein 1	Mus musculus	64-69
34561933-7	2021	Furthermore, overexpression of HIF-2alpha in chondrocytes by Ad-Epas1 intra-articular injection abolished the chondroprotective effect of D-mannose during OA progression and eliminated the role of D-mannose as a ferroptosis suppressor.	Mannose	197-206	endothelial PAS domain protein 1	Mus musculus	31-41
34561933-7	2021	Furthermore, overexpression of HIF-2alpha in chondrocytes by Ad-Epas1 intra-articular injection abolished the chondroprotective effect of D-mannose during OA progression and eliminated the role of D-mannose as a ferroptosis suppressor.	Mannose	197-206	endothelial PAS domain protein 1	Mus musculus	64-69
34561933-8	2021	CONCLUSIONS: D-mannose alleviates osteoarthritis progression by suppressing HIF-2alpha-mediated chondrocyte sensitivity to ferroptosis, indicating D-mannose to be a potential therapeutic strategy for ferroptosis-related diseases.	Mannose	13-22	endothelial PAS domain protein 1	Mus musculus	76-86
34561933-8	2021	CONCLUSIONS: D-mannose alleviates osteoarthritis progression by suppressing HIF-2alpha-mediated chondrocyte sensitivity to ferroptosis, indicating D-mannose to be a potential therapeutic strategy for ferroptosis-related diseases.	Mannose	147-156	endothelial PAS domain protein 1	Mus musculus	76-86
34380178-6	2021	Sugar composition analysis showed that mannose content in adherent mucilage of kjc1 and vtc1 mutants was only 42% and 11% of the wild-type, respectively, indicating a drastic decrease of galactoglucomannan.	Mannose	39-46	Glucose-1-phosphate adenylyltransferase family protein	Arabidopsis thaliana	88-92
34778211-10	2021	The relative abundance of all the three N-glycan types (high-mannose, hybrid, and complex) was determined in FUT8KO comparing to wild-type CHO cells.	Mannose	61-68	alpha-(1,6)-fucosyltransferase	Cricetulus griseus	109-115
34827788-7	2021	Many of the metabolites that were affected by CORT administration, such as mannose and glucose, were previously linked to increases in glycosylation and gluconeogenesis in chickens under conditions of production stress.	Mannose	75-82	CORT	Gallus gallus	46-50
34631661-11	2021	The relatively higher amount of high-mannose abundant sites (N17, N234, N343, N616, N709, N717, N801, and N1134) on HEK-Spike suggests that glycan-shielding may differ among the two constructs.	Mannose	37-44	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	120-125
34735875-0	2021	d-mannose attenuates lipopolysaccharide-induced osteolysis via CPT1A-Mediated lipid metabolic regulation in macrophages.	Mannose	0-9	carnitine palmitoyltransferase 1a, liver	Mus musculus	63-68
34735875-6	2021	Mechanically, d-mannose recovers LPS-suppressed Cpt1a transcription and promotes lipid metabolism of macrophage.	Mannose	14-23	carnitine palmitoyltransferase 1a, liver	Mus musculus	48-53
34735875-7	2021	Treatment with etomoxir, an inhibitor of CPT1A, abolishes the effects of d-mannose on LPS-treated macrophage in vitro and eliminates its protection against osteolysis in vivo.	Mannose	73-82	carnitine palmitoyltransferase 1a, liver	Mus musculus	41-46
34735875-8	2021	Collectively, our results imply that d-mannose attenuates LPS-induced osteolysis by manipulating CPT1A-mediated lipid metabolism in macrophages.	Mannose	37-46	carnitine palmitoyltransferase 1a, liver	Mus musculus	97-102
34536421-5	2021	Crystallographic studies of CD1c complexes with these three new MPM analogs showed anchoring of the lipid tail and phosphate group that is highly comparable to nature-identical MPM, with considerable conformational flexibility for the mannose head group.	Mannose	235-242	CD1c molecule	Homo sapiens	28-32
34474461-2	2021	Nitrobenzoxadiazole and mannose conjugated NBD-Man-CA was found to be selectively recognized by GLUT1 and act as a "molecular carrier" for selective tumor targeting.	Mannose	24-31	solute carrier family 2 member 1	Homo sapiens	96-101
34127216-3	2021	SHPS-1 consisted of arabinose, mannose, glucose, and galactose at a molar ratio of 2.2:15.7:49.3:32.8.	Mannose	31-38	signal-regulatory protein alpha	Mus musculus	0-6
34535746-7	2021	PIGG encodes for a transferase, GPI-ethanolaminephosphate transferase II, which adds ethanolamine phosphate (EtNP) to the second mannose in a GPI-anchor.	Mannose	129-136	phosphatidylinositol glycan anchor biosynthesis class G	Homo sapiens	0-4
34567092-5	2021	The presence in the patient"s serum of the pathognomonic N-linked mannose-deprived tetrasaccharide marker for ALG1-CDG (Neu5Acalpha2,6Galbeta1,4-GlcNAcbeta1,4GlcNAc) further supported this diagnosis.	Mannose	66-73	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	110-114
34246701-5	2021	Here, IMD-0354, inhibitor of NF-kappaB pathway was loaded in mannose modified lipid nanoparticles (M-IMD-LNP).	Mannose	61-68	nuclear factor kappa B subunit 1	Homo sapiens	29-38
34504130-2	2021	Orysata, a mannose-binding lectin from rice, has been reported to exert immunomodulatory activities on insect cells.	Mannose	11-18	lectin-37Db	Drosophila melanogaster	27-33
34511962-4	2021	This susceptibility to mannose depends on the levels of phosphomannose isomerase (PMI).	Mannose	23-30	mannose phosphate isomerase	Homo sapiens	56-80
34511962-4	2021	This susceptibility to mannose depends on the levels of phosphomannose isomerase (PMI).	Mannose	23-30	mannose phosphate isomerase	Homo sapiens	82-85
34511962-5	2021	The cancer cells with lower levels of PMI are more sensitive to mannose than cells with higher levels.	Mannose	64-71	mannose phosphate isomerase	Homo sapiens	38-41
34242650-3	2021	GRP94 binds to SI exclusively via its mannose-rich form compatible with an interaction occurring in the ER.	Mannose	38-45	heat shock protein 90 beta family member 1	Homo sapiens	0-5
34462883-5	2022	The results showed that levels of multi-antennary branched, alpha2,6-sialylated, and galactosylated N-glycans increased, while high-mannose typed and fucosylated N-glycans decreased in the serum of Cav-1-/- mice, compared with that of wild-type mice.	Mannose	132-139	caveolin 1, caveolae protein	Mus musculus	198-203
34380532-0	2021	Mannose supplementation in PMM2-CDG.	Mannose	0-7	phosphomannomutase 2	Homo sapiens	27-31
34380532-2	2021	Our paper "Dietary mannose supplementation in phosphomannomutase 2 deficiency (PMM2-CDG)" has shown that further investigation of mannose in PMM2-CDG is worthwhile alongside other treatment options and should not be dismissed off-hand without the willingness to prove or disprove it in controlled prospective clinical trials.	Mannose	19-26	phosphomannomutase 2	Homo sapiens	79-83
34291736-3	2021	Here, we report that the C-type lectin receptor L-SIGN interacted in a Ca2+-dependent manner with high-mannose-type N-glycans on the SARS-CoV-2 spike protein.	Mannose	103-110	C-type lectin domain family 4 member M	Homo sapiens	48-54
34286584-0	2021	Nanoparticles for Directed Immunomodulation: Mannose-Functionalized Glycodendrimers Induce Interleukin-8 in Myeloid Cell Lines.	Mannose	45-52	C-X-C motif chemokine ligand 8	Homo sapiens	91-104
34987125-0	2021	The correlation between amylin and insulin by treatment with 2-deoxy-D-glucose and/or mannose in rat insulinoma ins-1E cells.	Mannose	86-93	islet amyloid polypeptide	Rattus norvegicus	24-30
34987125-4	2021	Here, we reported the correlation between amylin and insulin in rat insulinoma INS-1E cells by treating 2-deoxy-D-glucose (2-DG) and/or mannose.	Mannose	136-143	islet amyloid polypeptide	Rattus norvegicus	42-48
34987125-10	2021	These data suggest the relative correlation to the synthesis of amylin by cells vs. the secretion into the media, the synthesis of amylin vs. insulin, and the secretion of amylin vs. insulin under 2-DG and/or mannose in rat insulinoma INS-1E cells.	Mannose	209-216	islet amyloid polypeptide	Rattus norvegicus	64-70
34987125-10	2021	These data suggest the relative correlation to the synthesis of amylin by cells vs. the secretion into the media, the synthesis of amylin vs. insulin, and the secretion of amylin vs. insulin under 2-DG and/or mannose in rat insulinoma INS-1E cells.	Mannose	209-216	islet amyloid polypeptide	Rattus norvegicus	172-178
34061468-4	2021	Here, we demonstrate that mannose-functionalized poly- l -lysine glycoconjugates efficiently inhibit the attachment of viral glycoproteins to DC-SIGN-presenting cells with picomolar affinity.	Mannose	26-33	CD209 molecule	Homo sapiens	142-149
34313879-4	2021	The enhancement of MPI expression was in response to DNA damage gene, and ATM inhibitor was verified as a potential drug with a synergistic effect with mannose on HSC-3.	Mannose	152-159	ATM serine/threonine kinase	Homo sapiens	74-77
34313879-6	2021	Finally, mannose could reverse immunophenotyping caused by antibiotics in mice, resulting in the decrease of CD8+ T cells and increase of myeloid-derived suppressor cells (MDSCs).	Mannose	9-16	CD8a molecule	Homo sapiens	109-112
34313879-8	2021	The treatment of ATM inhibitor, immune regulating cells of CD8+ T cells and MDSCs, and oral microbiomes in combination with mannose could exhibit co-inhibitory therapeutic effect for OSCC.	Mannose	124-131	ATM serine/threonine kinase	Homo sapiens	17-20
34313879-8	2021	The treatment of ATM inhibitor, immune regulating cells of CD8+ T cells and MDSCs, and oral microbiomes in combination with mannose could exhibit co-inhibitory therapeutic effect for OSCC.	Mannose	124-131	CD8a molecule	Homo sapiens	59-62
34291736-3	2021	Here, we report that the C-type lectin receptor L-SIGN interacted in a Ca2+-dependent manner with high-mannose-type N-glycans on the SARS-CoV-2 spike protein.	Mannose	103-110	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	144-149
34181654-1	2021	Our previous studies showed that MAN3-mediated mannose plays an important role in plant responses to cadmium (Cd) stress.	Mannose	47-54	Glycosyl hydrolase superfamily protein	Arabidopsis thaliana	33-37
34356378-2	2021	The results showed that GLP-1 and GLP-2 were mainly composed of mannose, glucose, galactose, xylose, and arabinose, with weight-average molecular weights of 6.31 and 14.07 kDa, respectively.	Mannose	64-71	glucagon	Mus musculus	24-29
34181654-6	2021	Moreover, we found that mannose is able to bind to the GNA-related domain of MNB1, and that mannose binding to the GNA-related domain of MNB1 is required for MAN3-mediated Cd tolerance in Arabidopsis.	Mannose	24-31	Glycosyl hydrolase superfamily protein	Arabidopsis thaliana	158-162
34181654-6	2021	Moreover, we found that mannose is able to bind to the GNA-related domain of MNB1, and that mannose binding to the GNA-related domain of MNB1 is required for MAN3-mediated Cd tolerance in Arabidopsis.	Mannose	92-99	Glycosyl hydrolase superfamily protein	Arabidopsis thaliana	158-162
34258484-0	2021	Inactivating the mannose-ethanolamine phosphotransferase Gpi7 confers caspofungin resistance in the human fungal pathogen Candida albicans.	Mannose	17-24	phosphatidylinositol glycan anchor biosynthesis class G	Homo sapiens	57-61
34258484-3	2021	A mutant exhibiting the highest resistance possessed a transposon insertion that inactivates GPI7, a gene encoding the mannose-ethanolamine phosphotransferase.	Mannose	119-126	phosphatidylinositol glycan anchor biosynthesis class G	Homo sapiens	93-97
34332121-6	2021	The dataset created for identifying the EDEM2 glyco-clients carrying high mannose/hybrid N-glycans provides a comprehensive N-glycosites analysis mapping over 1000 N-glycosites on more than 600 melanoma glycoproteins.	Mannose	74-81	ER degradation enhancing alpha-mannosidase like protein 2	Homo sapiens	40-45
35533849-4	2022	RRP consisted of glucose, galacturonic acid, mannose, rhamnose, galactose, arabinose, xylose, and glucuronic acid (molar ratio: 7.78:7.59:4.23:3.22:3.15:1.65:1.00), with Mw of 327.92 kDa.	Mannose	45-52	ribosome binding protein 1	Homo sapiens	0-3
35543349-7	2022	Furthermore, liver metabolomics based on UPLC-QTOF/MS demonstrated that oral administration of GAA had a significant regulatory effect on the composition of liver metabolites in mice exposed to alcohol intake, especially the levels of the biomarkers involved in the metabolic pathways of riboflavin metabolism, glycine, serine and threonine metabolism, pyruvate metabolism, glycolysis/gluconeogenesis, biosynthesis of unsaturated fatty acids, synthesis and degradation of ketone bodies, fructose and mannose metabolism.	Mannose	500-507	glucosidase, alpha, acid	Mus musculus	95-98
35490896-0	2022	Mannose inhibits proliferation and promotes apoptosis to enhance sensitivity of glioma cells to temozolomide through Wnt/beta-catenin signaling pathway.	Mannose	0-7	catenin beta 1	Homo sapiens	121-133
35490896-9	2022	Mannose enhanced the sensitivity of glioma cells to TMZ, indicated by the further inhibited cell viability and colony formation and the aggravated cell apoptosis, which was reversed by overexpression of O6-methylguanine DNA methyltransferase (MGMT).	Mannose	0-7	O-6-methylguanine-DNA methyltransferase	Homo sapiens	203-241
35490896-9	2022	Mannose enhanced the sensitivity of glioma cells to TMZ, indicated by the further inhibited cell viability and colony formation and the aggravated cell apoptosis, which was reversed by overexpression of O6-methylguanine DNA methyltransferase (MGMT).	Mannose	0-7	O-6-methylguanine-DNA methyltransferase	Homo sapiens	243-247
35490896-10	2022	Furthermore, mannose and TMZ inhibited MGMT expression and Wnt/beta-catenin activation.	Mannose	13-20	O-6-methylguanine-DNA methyltransferase	Homo sapiens	39-43
35490896-10	2022	Furthermore, mannose and TMZ inhibited MGMT expression and Wnt/beta-catenin activation.	Mannose	13-20	catenin beta 1	Homo sapiens	63-75
35490896-11	2022	Moreover, activating Wnt/beta-catenin pathway blocked anti-proliferative effect induced by mannose and TMZ, which was further suppressed by overexpressed MGMT.	Mannose	91-98	catenin beta 1	Homo sapiens	25-37
35490896-11	2022	Moreover, activating Wnt/beta-catenin pathway blocked anti-proliferative effect induced by mannose and TMZ, which was further suppressed by overexpressed MGMT.	Mannose	91-98	O-6-methylguanine-DNA methyltransferase	Homo sapiens	154-158
35490896-12	2022	Mannose inhibited glioma growth, suppressed Ki67 and downregulated MGMT and beta-catenin in vivo.	Mannose	0-7	O-6-methylguanine-DNA methyltransferase	Homo sapiens	67-71
35490896-12	2022	Mannose inhibited glioma growth, suppressed Ki67 and downregulated MGMT and beta-catenin in vivo.	Mannose	0-7	catenin beta 1	Homo sapiens	76-88
35490896-13	2022	CONCLUSION: Mannose inhibited MGMT to enhance sensitivity of glioma cells to TMZ, with Wnt/beta-catenin pathway involvement.	Mannose	12-19	O-6-methylguanine-DNA methyltransferase	Homo sapiens	30-34
35490896-13	2022	CONCLUSION: Mannose inhibited MGMT to enhance sensitivity of glioma cells to TMZ, with Wnt/beta-catenin pathway involvement.	Mannose	12-19	catenin beta 1	Homo sapiens	91-103
35490896-14	2022	Our data suggested that mannose could be an innovative agent to improve glioma treatment, particularly in TMZ-resistant glioma with high MGMT.	Mannose	24-31	O-6-methylguanine-DNA methyltransferase	Homo sapiens	137-141
35337516-3	2022	The heteropolysaccharide ARP-1 was composed of fucose, arabinose, galactose, glucose and mannose with a molar ratio of 0.40:14.25:10.22:1.06:0.41.	Mannose	89-96	nuclear receptor subfamily 2, group F, member 2	Rattus norvegicus	25-30
35258157-6	2022	Overexpression of SlIMP3 also increased uronic acid, rhamnose, xylose, mannose, and galactose content in cell wall of fruit.	Mannose	71-78	inositol monophosphatase 3	Solanum lycopersicum	18-24
35603428-3	2022	It is postulated that EthN-P on the third mannose (EthN-P-Man3) is the bridge between GPI and the protein and the second (EthN-P-Man2) is removed after GPI-protein attachment.	Mannose	42-49	glucose-6-phosphate isomerase	Homo sapiens	86-89
35628619-2	2022	In Asn (N)-linked glycosylation, a complex and ubiquitous cotranslational and post-translational protein modification required for the transfer of correctly folded proteins and endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins, ALG12 (EBS4) is an alpha 1, 6-mannosyltransferase catalyzing a mannose into Glc3Man9GlcNAc2.	Mannose	315-322	homolog of asparagine-linked glycosylation 12	Arabidopsis thaliana	252-257
35628619-2	2022	In Asn (N)-linked glycosylation, a complex and ubiquitous cotranslational and post-translational protein modification required for the transfer of correctly folded proteins and endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins, ALG12 (EBS4) is an alpha 1, 6-mannosyltransferase catalyzing a mannose into Glc3Man9GlcNAc2.	Mannose	315-322	homolog of asparagine-linked glycosylation 12	Arabidopsis thaliana	259-263
35586945-5	2022	AMAN-2 functions cell-autonomously to allow for decoration of the neuronal transmembrane receptor DMA-1/LRR-TM with the correct set of high-mannose/hybrid/paucimannose N-glycans.	Mannose	140-147	Alpha-mannosidase	Caenorhabditis elegans	0-6
35524566-3	2022	We herein report for the first time the targeted delivery of CD206-targetable chemically modified mannose-siRNA (CMM-siRNA) conjugates to macrophages and dendritic cells (DCs).	Mannose	98-105	mannose receptor C-type 1	Homo sapiens	61-66
35586945-5	2022	AMAN-2 functions cell-autonomously to allow for decoration of the neuronal transmembrane receptor DMA-1/LRR-TM with the correct set of high-mannose/hybrid/paucimannose N-glycans.	Mannose	140-147	LRRCT domain-containing protein	Caenorhabditis elegans	98-103
35202634-1	2022	In this study, a novel low molecular weight polysaccharide (named LMW-BSP) was extracted from Bletilla striata at 4  C. The results of structural characteristics analysis showed that LMW-BSP was a 23 kDa neutral polysaccharide contained glucose and mannose at a molar ratio of 1.00:1.26.	Mannose	249-256	black spleen	Mus musculus	187-190
35588979-3	2022	The monosaccharide composition of MSP-1 was mannose and glucose at a ratio of 1.00: 1.25.	Mannose	44-51	salivary protein electrophoretic 1, regulator	Mus musculus	34-39
35231685-5	2022	The monomodal distributed mannose-decorated nanoparticles are in the range of nanometric size (RH < 115 nm) with PdI < 0.20 and good encapsulation efficiency (DEE = 46.15% for CL and 76.20% for IMC).	Mannose	26-33	peptidyl arginine deiminase 1	Homo sapiens	113-116
35470665-1	2022	Dense glycosylation and the trimeric conformation of the human immunodeficiency virus-1 (HIV-1) envelope protein limit the accessibility of some cellular glycan processing enzymes and end up with high-mannose-type N-linked glycans on the envelope spike, among which the Man5GlcNAc2 structure occupies a certain proportion.	Mannose	201-208	endogenous retrovirus group K member 6, envelope	Homo sapiens	96-112
35432728-14	2022	The monosaccharide content of ABP included galacturonic acid (45.19%), galactose (36.63%), arabinose rhamnose (12.13%), and mannose (6.05%).	Mannose	124-131	glutamate receptor interacting protein 2	Rattus norvegicus	30-33
35478050-0	2022	Photodynamic therapy using mannose-conjugated chlorin e6 increases cell surface calreticulin in cancer cells and promotes macrophage phagocytosis.	Mannose	27-34	calreticulin	Homo sapiens	80-92
35380569-2	2022	We tested C2 triazole-modified mono- and pseudo-di-mannosides as inhibitors of DC/L-SIGN binding to a model mannosylated protein (Man-BSA) and to SARS-CoV2 spike, finding that they inhibit the interaction of both lectins with the spike glycoprotein in a Surface Plasmon Resonance (SPR) assay and are more potent than mannose by up to 36-fold (DC-SIGN) and 10-fold (L-SIGN).	Mannose	317-324	C-type lectin domain family 4 member M	Homo sapiens	82-88
35378038-2	2022	The first specific mannose-binding lectin-associated serine protease (MASP) inhibitors had been developed from the 14-amino-acid sunflower trypsin inhibitor (SFTI) peptide by phage display, yielding SFTI-based MASP inhibitors, SFMIs.	Mannose	19-26	MBL associated serine protease 1	Homo sapiens	70-74
35378038-2	2022	The first specific mannose-binding lectin-associated serine protease (MASP) inhibitors had been developed from the 14-amino-acid sunflower trypsin inhibitor (SFTI) peptide by phage display, yielding SFTI-based MASP inhibitors, SFMIs.	Mannose	19-26	MBL associated serine protease 1	Homo sapiens	210-214
35411940-3	2022	These glycans can be recognised by mannose-binding lectins, including the mannose receptor (CD206), expressed on macrophages and specialised phagocytic endothelial cells in the spleen to mediate the extravascular haemolysis characteristic of these diseases.	Mannose	35-42	mannose receptor C-type 1	Homo sapiens	92-97
35464439-0	2022	D-Mannose Regulates Hepatocyte Lipid Metabolism via PI3K/Akt/mTOR Signaling Pathway and Ameliorates Hepatic Steatosis in Alcoholic Liver Disease.	Mannose	0-9	thymoma viral proto-oncogene 1	Mus musculus	57-60
35464439-0	2022	D-Mannose Regulates Hepatocyte Lipid Metabolism via PI3K/Akt/mTOR Signaling Pathway and Ameliorates Hepatic Steatosis in Alcoholic Liver Disease.	Mannose	0-9	mechanistic target of rapamycin kinase	Mus musculus	61-65
35464439-4	2022	Meanwhile, D-mannose regulated lipid metabolism by rescuing ethanol-mediated reduction of fatty acid oxidation genes (PPARalpha, ACOX1, CPT1) and elevation of lipogenic genes (SREBP1c, ACC1, FASN).	Mannose	11-20	peroxisome proliferator activated receptor alpha	Mus musculus	118-127
35464439-4	2022	Meanwhile, D-mannose regulated lipid metabolism by rescuing ethanol-mediated reduction of fatty acid oxidation genes (PPARalpha, ACOX1, CPT1) and elevation of lipogenic genes (SREBP1c, ACC1, FASN).	Mannose	11-20	acyl-Coenzyme A oxidase 1, palmitoyl	Mus musculus	129-134
35464439-4	2022	Meanwhile, D-mannose regulated lipid metabolism by rescuing ethanol-mediated reduction of fatty acid oxidation genes (PPARalpha, ACOX1, CPT1) and elevation of lipogenic genes (SREBP1c, ACC1, FASN).	Mannose	11-20	carnitine palmitoyltransferase 1b, muscle	Mus musculus	136-140
35464439-4	2022	Meanwhile, D-mannose regulated lipid metabolism by rescuing ethanol-mediated reduction of fatty acid oxidation genes (PPARalpha, ACOX1, CPT1) and elevation of lipogenic genes (SREBP1c, ACC1, FASN).	Mannose	11-20	sterol regulatory element binding transcription factor 1	Mus musculus	176-183
35464439-4	2022	Meanwhile, D-mannose regulated lipid metabolism by rescuing ethanol-mediated reduction of fatty acid oxidation genes (PPARalpha, ACOX1, CPT1) and elevation of lipogenic genes (SREBP1c, ACC1, FASN).	Mannose	11-20	acetyl-Coenzyme A carboxylase alpha	Mus musculus	185-189
35464439-4	2022	Meanwhile, D-mannose regulated lipid metabolism by rescuing ethanol-mediated reduction of fatty acid oxidation genes (PPARalpha, ACOX1, CPT1) and elevation of lipogenic genes (SREBP1c, ACC1, FASN).	Mannose	11-20	fatty acid synthase	Mus musculus	191-195
35433513-4	2022	In vitro, C5a stimulation enhanced mannose expression in and facilitated bacterial adhesion/colonization to human bladder epithelial cells.	Mannose	35-42	complement C5a receptor 1	Homo sapiens	10-13
35464439-5	2022	PI3K/Akt/mTOR signaling pathway was involved in this effect of D-mannose on lipid metabolism since PI3K/Akt/mTOR pathway inhibitors or agonists could abolish this effect in PMHs.	Mannose	63-72	thymoma viral proto-oncogene 1	Mus musculus	5-8
35464439-5	2022	PI3K/Akt/mTOR signaling pathway was involved in this effect of D-mannose on lipid metabolism since PI3K/Akt/mTOR pathway inhibitors or agonists could abolish this effect in PMHs.	Mannose	63-72	mechanistic target of rapamycin kinase	Mus musculus	9-13
35464439-5	2022	PI3K/Akt/mTOR signaling pathway was involved in this effect of D-mannose on lipid metabolism since PI3K/Akt/mTOR pathway inhibitors or agonists could abolish this effect in PMHs.	Mannose	63-72	thymoma viral proto-oncogene 1	Mus musculus	104-107
35464439-5	2022	PI3K/Akt/mTOR signaling pathway was involved in this effect of D-mannose on lipid metabolism since PI3K/Akt/mTOR pathway inhibitors or agonists could abolish this effect in PMHs.	Mannose	63-72	mechanistic target of rapamycin kinase	Mus musculus	108-112
35464439-6	2022	Overall, our findings suggest that D-mannose exhibits its anti-steatosis effect in ALD by regulating hepatocyte lipid metabolism via PI3K/Akt/mTOR signaling pathway.	Mannose	35-44	thymoma viral proto-oncogene 1	Mus musculus	138-141
35464439-6	2022	Overall, our findings suggest that D-mannose exhibits its anti-steatosis effect in ALD by regulating hepatocyte lipid metabolism via PI3K/Akt/mTOR signaling pathway.	Mannose	35-44	mechanistic target of rapamycin kinase	Mus musculus	142-146
35178612-4	2022	We analyzed the thermodynamic properties of SD1 compared to full-size SVN (produced in E. coli) by isothermal titration and differential scanning calorimetry to characterize the specific interactions between SVN/SD1 and gp120 as well as to high-mannose oligosaccharides.	Mannose	245-252	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	220-225
34998886-2	2022	SCP-1 was a heteropolysaccharide mainly comprising glucose, galactose, fucose, and mannose in a molar ratio of 52.10: 31.10: 15.04: 1.76.	Mannose	83-90	stem cell proliferation 1	Mus musculus	0-5
35306756-5	2022	Furthermore, a Toll-like receptor (TLR) 7/8 agonist-conjugated polymer, anchored on the surface of CuS, is modified with mannose to bind with DCs in the tumor microenvironment.	Mannose	121-128	toll like receptor 7	Homo sapiens	15-43
35306756-7	2022	Mannose-modified polymer-TLR7/8 agonist conjugates are subsequently exposed, leading to the activation of DCs and proliferation of T cells.	Mannose	0-7	toll like receptor 7	Homo sapiens	25-31
35092721-2	2022	In this study, a mannose-modified HMGB1-siRNA loaded stable nucleic acid lipid particle delivery system (mLNP-siHMGB1) was constructed to target liver macrophages with mannose receptor mediation, thereby silencing HMGB1 protein expression and treating NASH.	Mannose	17-24	high mobility group box 1	Mus musculus	34-39
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	ALG3 alpha-1,3- mannosyltransferase	Homo sapiens	72-76
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	79-83
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	ALG11 alpha-1,2-mannosyltransferase	Homo sapiens	86-91
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	ALG12 alpha-1,6-mannosyltransferase	Homo sapiens	94-99
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	RFT1 homolog	Homo sapiens	102-106
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	steroid 5 alpha-reductase 3	Homo sapiens	109-115
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	dolichol kinase	Homo sapiens	118-122
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	125-129
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	dolichyl-phosphate mannosyltransferase subunit 3, regulatory	Homo sapiens	132-136
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	mannose-P-dolichol utilization defect 1	Homo sapiens	139-144
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	Mannose	30-37	ALG13 UDP-N-acetylglucosaminyltransferase subunit	Homo sapiens	147-152
35279850-8	2022	Further differential analysis revealed high-mannose profiles, characteristic for ALG12- and ALG9-CDG.	Mannose	44-51	ALG12 alpha-1,6-mannosyltransferase	Homo sapiens	81-86
35279850-8	2022	Further differential analysis revealed high-mannose profiles, characteristic for ALG12- and ALG9-CDG.	Mannose	44-51	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	92-96
35151934-5	2022	Mannose, as a simple natural ligand, can selectively bind to TAM surface CD206 (macrophage mannose receptor, MMR).	Mannose	0-7	mannose receptor, C type 1	Mus musculus	73-78
35151934-5	2022	Mannose, as a simple natural ligand, can selectively bind to TAM surface CD206 (macrophage mannose receptor, MMR).	Mannose	0-7	ATPase, class II, type 9B	Mus musculus	109-112
34981854-6	2022	Our data demonstrate that FGFR4 has multiple glycoforms, with predominant bands relating to the full-length receptor that has a high mannose- or hybrid-type form and a complex-type glycan form.	Mannose	133-140	fibroblast growth factor receptor 4	Homo sapiens	26-31
34981854-10	2022	Inhibition of glycosylation using NGI-1, an oligosaccharyltransferase inhibitor, reduced both high mannose- or hybrid- and complex-type glycan forms of FGFR4, increased processing and sensitized to apoptosis.	Mannose	99-106	fibroblast growth factor receptor 4	Homo sapiens	152-157
35092721-2	2022	In this study, a mannose-modified HMGB1-siRNA loaded stable nucleic acid lipid particle delivery system (mLNP-siHMGB1) was constructed to target liver macrophages with mannose receptor mediation, thereby silencing HMGB1 protein expression and treating NASH.	Mannose	17-24	high mobility group box 1	Mus musculus	214-219
35092721-2	2022	In this study, a mannose-modified HMGB1-siRNA loaded stable nucleic acid lipid particle delivery system (mLNP-siHMGB1) was constructed to target liver macrophages with mannose receptor mediation, thereby silencing HMGB1 protein expression and treating NASH.	Mannose	168-175	high mobility group box 1	Mus musculus	34-39
35092721-2	2022	In this study, a mannose-modified HMGB1-siRNA loaded stable nucleic acid lipid particle delivery system (mLNP-siHMGB1) was constructed to target liver macrophages with mannose receptor mediation, thereby silencing HMGB1 protein expression and treating NASH.	Mannose	168-175	high mobility group box 1	Mus musculus	214-219
35203704-8	2022	When transfected with the different modified chitosan formulations, significantly (p < 0.05) higher VGF expression was observed in primary astrocytes and neurons using the mannose, Tat peptide, and oleic acid grafted chitosan polymer.	Mannose	172-179	VGF nerve growth factor inducible	Mus musculus	100-103
35296088-8	2022	The decreased AKT/mTOR/HIF-1alpha signaling and glycolytic ability may contribute to the suppression of gammadelta T cells achieved by D-mannose.	Mannose	135-144	thymoma viral proto-oncogene 1	Mus musculus	14-17
35296088-8	2022	The decreased AKT/mTOR/HIF-1alpha signaling and glycolytic ability may contribute to the suppression of gammadelta T cells achieved by D-mannose.	Mannose	135-144	mechanistic target of rapamycin kinase	Mus musculus	18-22
35296088-8	2022	The decreased AKT/mTOR/HIF-1alpha signaling and glycolytic ability may contribute to the suppression of gammadelta T cells achieved by D-mannose.	Mannose	135-144	hypoxia inducible factor 1, alpha subunit	Mus musculus	23-33
35181605-0	2022	D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1.	Mannose	0-9	CD274 antigen	Mus musculus	105-110
35181605-5	2022	Here, we show that D-mannose can significantly facilitate TNBC treatment via degradation of PD-L1.	Mannose	19-28	CD274 molecule	Homo sapiens	92-97
35181605-6	2022	Specifically, D-mannose can activate AMP-activated protein kinase (AMPK) to phosphorylate PD-L1 at S195, which leads to abnormal glycosylation and proteasomal degradation of PD-L1.	Mannose	14-23	CD274 molecule	Homo sapiens	90-95
35181605-6	2022	Specifically, D-mannose can activate AMP-activated protein kinase (AMPK) to phosphorylate PD-L1 at S195, which leads to abnormal glycosylation and proteasomal degradation of PD-L1.	Mannose	14-23	CD274 molecule	Homo sapiens	174-179
35181605-11	2022	Our study unveils a mechanism by which D-mannose targets PD-L1 for degradation and provides methods to facilitate immunotherapy and radiotherapy in TNBC.	Mannose	39-48	CD274 antigen	Mus musculus	57-62
35264966-6	2022	The average molecular weight of ABP was 18.3 kDa and ABP consisted of glucose, mannose, galactose, xylose, galacturonic acid, glucuronic acid at a molar ratio of 37.8:8:2.5:1.7:1:1.	Mannose	79-86	amine oxidase, copper-containing 1	Mus musculus	32-35
35264966-6	2022	The average molecular weight of ABP was 18.3 kDa and ABP consisted of glucose, mannose, galactose, xylose, galacturonic acid, glucuronic acid at a molar ratio of 37.8:8:2.5:1.7:1:1.	Mannose	79-86	amine oxidase, copper-containing 1	Mus musculus	53-56
35112843-6	2022	The two-stage cascade recognition process significantly increases the ER affinity of the CD probe, thus allowing the following evaluation of ER stress by tracking autophagy-induced mannose transfer from the ER to the cytoplasm.	Mannose	181-188	epiregulin	Homo sapiens	207-209
35112843-5	2022	Next, the CD probe can specifically anchor on the ER membrane via recognition between boronic acids and o-dihydroxy groups of mannose in the ER lumen.	Mannose	126-133	epiregulin	Homo sapiens	50-52
35112843-5	2022	Next, the CD probe can specifically anchor on the ER membrane via recognition between boronic acids and o-dihydroxy groups of mannose in the ER lumen.	Mannose	126-133	epiregulin	Homo sapiens	141-143
35201482-0	2022	Mannose enhances the radio-sensitivity of esophageal squamous cell carcinoma with low MPI expression by suppressing glycolysis.	Mannose	0-7	mannose phosphate isomerase	Homo sapiens	86-89
35112843-6	2022	The two-stage cascade recognition process significantly increases the ER affinity of the CD probe, thus allowing the following evaluation of ER stress by tracking autophagy-induced mannose transfer from the ER to the cytoplasm.	Mannose	181-188	epiregulin	Homo sapiens	70-72
35112843-6	2022	The two-stage cascade recognition process significantly increases the ER affinity of the CD probe, thus allowing the following evaluation of ER stress by tracking autophagy-induced mannose transfer from the ER to the cytoplasm.	Mannose	181-188	epiregulin	Homo sapiens	141-143
35136180-2	2022	Alg2 mannosyltransferase adds both the alpha1,3- and alpha1,6-mannose (Man) onto ManGlcNAc2-pyrophosphate-dolichol (M1Gn2-PDol) in either order to generate the branched M3Gn2-PDol product.	Mannose	71-74	ALG2 alpha-1,3/1,6-mannosyltransferase	Homo sapiens	0-4
35142655-6	2022	Mannose treatment of PCa cells induced changes in mitochondrial morphology, caused dysregulated expression of the fission protein, such as fission, mitochondrial 1 (FIS1), and enhanced the expression of proapoptotic factors, such as BCL2-associated X (Bax) and BCL2-antagonist/killer 1 (Bak).	Mannose	0-7	fission, mitochondrial 1	Homo sapiens	114-121
35142655-6	2022	Mannose treatment of PCa cells induced changes in mitochondrial morphology, caused dysregulated expression of the fission protein, such as fission, mitochondrial 1 (FIS1), and enhanced the expression of proapoptotic factors, such as BCL2-associated X (Bax) and BCL2-antagonist/killer 1 (Bak).	Mannose	0-7	fission, mitochondrial 1	Homo sapiens	139-163
35142655-6	2022	Mannose treatment of PCa cells induced changes in mitochondrial morphology, caused dysregulated expression of the fission protein, such as fission, mitochondrial 1 (FIS1), and enhanced the expression of proapoptotic factors, such as BCL2-associated X (Bax) and BCL2-antagonist/killer 1 (Bak).	Mannose	0-7	fission, mitochondrial 1	Homo sapiens	165-169
35142655-6	2022	Mannose treatment of PCa cells induced changes in mitochondrial morphology, caused dysregulated expression of the fission protein, such as fission, mitochondrial 1 (FIS1), and enhanced the expression of proapoptotic factors, such as BCL2-associated X (Bax) and BCL2-antagonist/killer 1 (Bak).	Mannose	0-7	BCL2 associated X, apoptosis regulator	Homo sapiens	233-250
35142655-6	2022	Mannose treatment of PCa cells induced changes in mitochondrial morphology, caused dysregulated expression of the fission protein, such as fission, mitochondrial 1 (FIS1), and enhanced the expression of proapoptotic factors, such as BCL2-associated X (Bax) and BCL2-antagonist/killer 1 (Bak).	Mannose	0-7	BCL2 associated X, apoptosis regulator	Homo sapiens	252-255
35142655-6	2022	Mannose treatment of PCa cells induced changes in mitochondrial morphology, caused dysregulated expression of the fission protein, such as fission, mitochondrial 1 (FIS1), and enhanced the expression of proapoptotic factors, such as BCL2-associated X (Bax) and BCL2-antagonist/killer 1 (Bak).	Mannose	0-7	BCL2 antagonist/killer 1	Homo sapiens	261-285
35142655-6	2022	Mannose treatment of PCa cells induced changes in mitochondrial morphology, caused dysregulated expression of the fission protein, such as fission, mitochondrial 1 (FIS1), and enhanced the expression of proapoptotic factors, such as BCL2-associated X (Bax) and BCL2-antagonist/killer 1 (Bak).	Mannose	0-7	BCL2 antagonist/killer 1	Homo sapiens	287-290
35134154-4	2022	METHODS: A molecular, targeted immunotherapy method was developed by linking mannose-modified trimethyl chitosan (MTC) with Tollip-expressing plasmids via ionic cross-linking, forming MTC-Tollip nanoparticles with a targeting function.	Mannose	77-84	toll interacting protein	Homo sapiens	124-130
35134154-4	2022	METHODS: A molecular, targeted immunotherapy method was developed by linking mannose-modified trimethyl chitosan (MTC) with Tollip-expressing plasmids via ionic cross-linking, forming MTC-Tollip nanoparticles with a targeting function.	Mannose	77-84	toll interacting protein	Homo sapiens	188-194
35432971-2	2022	SCP-1-1 with a molecular weight of 440.0 kDa consisted of glucose and mannose.	Mannose	70-77	stem cell proliferation 1	Mus musculus	0-7
35014832-5	2022	In this study, we first purified the NEU1 from the isolated crystals produced by the HEK293 NEU1-KO cell transiently overexpressing the normal NEU1 and found that the N-glycans were high-mannose or complex types carrying terminal sialic acids.	Mannose	187-194	neuraminidase 1	Homo sapiens	37-41
35014832-5	2022	In this study, we first purified the NEU1 from the isolated crystals produced by the HEK293 NEU1-KO cell transiently overexpressing the normal NEU1 and found that the N-glycans were high-mannose or complex types carrying terminal sialic acids.	Mannose	187-194	neuraminidase 1	Homo sapiens	92-96
35014832-5	2022	In this study, we first purified the NEU1 from the isolated crystals produced by the HEK293 NEU1-KO cell transiently overexpressing the normal NEU1 and found that the N-glycans were high-mannose or complex types carrying terminal sialic acids.	Mannose	187-194	neuraminidase 1	Homo sapiens	143-147
35020773-0	2022	Correction: A Cationic-Independent Mannose 6-Phosphate Receptor Inhibitor (PXS64) Ameliorates Kidney Fibrosis by Inhibiting Activation of Transforming Growth Factor-beta1.	Mannose	35-42	transforming growth factor beta 1	Homo sapiens	138-170
35208951-5	2022	Further in vitro studies confirmed that mannose-, trehalose- and raffinose-treated LBP completely inhibited the hemagglutination ability towards rat red blood cells.	Mannose	40-47	lipopolysaccharide binding protein	Rattus norvegicus	83-86
35045343-3	2022	The catabolism of fOSs has been linked to the activity of a specific cytosolic mannosidase, MAN2C1, which cleaves alpha1,2-, alpha1,3-, and alpha1,6-mannose residues.	Mannose	148-156	mannosidase alpha class 2C member 1	Homo sapiens	92-98
35173766-1	2021	Background: Dolichyl-diphosphooligosaccharide-protein glycosyltransferase non-catalytic subunit (DDOST) is an important enzyme in the process of high-mannose oligosaccharide transferring in cells.	Mannose	150-157	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	12-95
35173766-1	2021	Background: Dolichyl-diphosphooligosaccharide-protein glycosyltransferase non-catalytic subunit (DDOST) is an important enzyme in the process of high-mannose oligosaccharide transferring in cells.	Mannose	150-157	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	97-102
35201482-14	2022	CONCLUSION: In esophageal cancer cell lines with low MPI expression, the administration of mannose was associated with enhanced radio-sensitivity.	Mannose	91-98	mannose phosphate isomerase	Homo sapiens	53-56
35127390-5	2022	After loading celastrol into mannose-modified liposomes, they effectively inhibited the expression of maturation markers, including CD80, CD86 and MHC-II, on DCs both in vitro and in vivo.	Mannose	29-36	CD80 antigen	Mus musculus	132-136
35127390-5	2022	After loading celastrol into mannose-modified liposomes, they effectively inhibited the expression of maturation markers, including CD80, CD86 and MHC-II, on DCs both in vitro and in vivo.	Mannose	29-36	CD86 antigen	Mus musculus	138-142
35127390-5	2022	After loading celastrol into mannose-modified liposomes, they effectively inhibited the expression of maturation markers, including CD80, CD86 and MHC-II, on DCs both in vitro and in vivo.	Mannose	29-36	histocompatibility-2, MHC	Mus musculus	147-153
35452398-9	2022	Whereas, ultra-endurance running and resistance training increased markers of the alternative (factor B and H), classical (C1s), and leptin (mannose binding lectin) pathways, as well as C3 and C6 family proteins, up to 72-h following exercise.	Mannose	141-148	leptin	Homo sapiens	133-139