PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
20724654-4	2010	Heparin-Sepharose (H-S) affinity chromatography was used for specific PLTP binding, and coeluted proteins were identified with MALDI-TOF mass spectrometry or Western blot analysis.	heparin-sepharose	19-22	phospholipid transfer protein	Homo sapiens	70-74
11039850-3	2000	Synthetic peptides containing a heparin-binding motif and encompassing residues F16-G33 or A74-S95 of TSP1 competed quantitatively with iodine 125-labeled TSP1 for binding to heparinagarose beads.	heparin-sepharose	175-189	thrombospondin 1	Homo sapiens	102-106
11039850-3	2000	Synthetic peptides containing a heparin-binding motif and encompassing residues F16-G33 or A74-S95 of TSP1 competed quantitatively with iodine 125-labeled TSP1 for binding to heparinagarose beads.	heparin-sepharose	175-189	thrombospondin 1	Homo sapiens	155-159
9771418-8	1998	By immunoblotting of heparinsepharose precipitates, TAKA-1 cells were shown to secrete FGF-5 into the medium.	heparin-sepharose	21-37	LOC101834793	Mesocricetus auratus	87-92
21533365-5	1997	This growth factor(s) bound to heparin Sepharose (HS) beads and its effects on cell proliferation were partially blocked by a neutralizing bFGF antibody.	heparin-sepharose	50-52	fibroblast growth factor 2	Mus musculus	139-143
2550068-4	1989	The major cytosolic form present in outdated platelets, PLC-II, was purified to homogeneity by chromatography on Fast Q-Sepharose, cellulose phosphate, heparin-agarose, phenyl-Sepharose, Superose 12, DEAE-5PW, and hydroxylapatite.	heparin-sepharose	152-167	phospholipase C gamma 1	Homo sapiens	56-62
3005456-1	1986	Platelet factor (PF4) prepared from human outdated platelets by heparinagarose affinity chromatography was confirmed to be chemotactic for human neutrophils and in a concentration-dependent fashion caused significant release of lysosomal enzymes (myeloperoxidase, lysozyme, beta-glucuronidase) from human neutrophils treated with cytochalasin B.	heparin-sepharose	64-78	platelet factor 4	Homo sapiens	17-20
6516292-1	1984	A single-step method is described for the isolation of a highly purified antithrombin III (AT III) concentrate at a recovery of over 30% using affinity chromatography on heparin-Sepharose (HS).	heparin-sepharose	189-191	serpin family C member 1	Homo sapiens	73-89
6516292-1	1984	A single-step method is described for the isolation of a highly purified antithrombin III (AT III) concentrate at a recovery of over 30% using affinity chromatography on heparin-Sepharose (HS).	heparin-sepharose	189-191	serpin family C member 1	Homo sapiens	91-97