PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
14718401-5	2004	Myocardial ET-1 peptide levels were significantly increased in binary transgenic (BT, ET+/tTA+) compared with nonbinary transgenic (NBT, ET+/tTA-; ET-/tTA+; ET-/tTA-) or DOX-treated BT littermates (40.1+/-4.7 versus 2.6+/-1.2 fmol/mL, P<0.003).	tta	90-93	endothelin 1	Mus musculus	11-15
22069466-6	2011	Thus, Env-mediated fusion of these two cell types allows the tTA to diffuse to the target cell and activate the expression of the F-Luc protein.	tta	61-64	endogenous retrovirus group K member 20	Homo sapiens	6-9
17596529-9	2007	Plasma ANG II concentration declined from 101 +/- 3 to 81 +/- 5 fmol/l after TTA treatment (P = 0.005).	tta	77-80	angiotensinogen	Rattus norvegicus	7-13
17596529-11	2007	In the nonclipped kidney, TTA did not change ANG I and moderately reduced ANG II levels.	tta	26-29	angiotensinogen	Rattus norvegicus	74-80
17596529-12	2007	The renal blood flow response to injection of ANG II into the nonclipped kidney was blunted compared with controls and normalized with TTA treatment (10 +/- 2 before vs. 20 +/- 2%, P < 0.001).	tta	135-138	angiotensinogen	Rattus norvegicus	46-52
17596529-13	2007	The results indicate that TTA downregulates the renin-angiotensin system in high renin animals but has no effect in low renin models.	tta	26-29	renin	Rattus norvegicus	48-53
17596529-13	2007	The results indicate that TTA downregulates the renin-angiotensin system in high renin animals but has no effect in low renin models.	tta	26-29	renin	Rattus norvegicus	81-86
17596529-13	2007	The results indicate that TTA downregulates the renin-angiotensin system in high renin animals but has no effect in low renin models.	tta	26-29	renin	Rattus norvegicus	81-86
16040568-5	2005	Herein, the treatments of adult males with the five antiandrogens were shown to affect the increased levels of tTA-driven hCYP1B1 expression in both dose-dependent and repeated experiments.	tta	111-114	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	122-129
16387452-7	2006	A cassette containing both sc rtTS and tTA was introduced into the Blm allele in ES cells and reduction of basal activity was observed upon doxycycline treatment.	tta	39-42	Bloom syndrome, RecQ like helicase	Mus musculus	67-70
14718401-5	2004	Myocardial ET-1 peptide levels were significantly increased in binary transgenic (BT, ET+/tTA+) compared with nonbinary transgenic (NBT, ET+/tTA-; ET-/tTA+; ET-/tTA-) or DOX-treated BT littermates (40.1+/-4.7 versus 2.6+/-1.2 fmol/mL, P<0.003).	tta	141-144	endothelin 1	Mus musculus	11-15
14718401-5	2004	Myocardial ET-1 peptide levels were significantly increased in binary transgenic (BT, ET+/tTA+) compared with nonbinary transgenic (NBT, ET+/tTA-; ET-/tTA+; ET-/tTA-) or DOX-treated BT littermates (40.1+/-4.7 versus 2.6+/-1.2 fmol/mL, P<0.003).	tta	141-144	endothelin 1	Mus musculus	11-15
17171126-6	1999	Circulating growth hormone (GH) and insulin-like growth factor-I (IGF-I) significantly decreased 6 months after surgery in all 14 acromegalic patients: normalization of plasma IGF-I levels was obtained in 4 of 5 patients after the endoscopic procedure and in 4 of 9 patients after TTA.	tta	281-284	insulin like growth factor 1	Homo sapiens	66-71
12100495-4	2002	In the TTA procedure, tyrosinase reacts with biotinyl tyramide, causing the substrate to deposit near the enzyme.	tta	7-10	tyrosinase	Homo sapiens	22-32
12100495-6	2002	In the skin and eye, TTA was highly specific for tyrosinase and served as a sensitive indicator of pigment cell distribution and status.	tta	21-24	tyrosinase	Homo sapiens	49-59
12831835-9	2003	Thus, the differential expression of the tTA-driven hCYP1B1 gene in the transgenic mice was caused by androgen, and it is possible that castrated male and adult female mice expressing the tTA-controlled hCYP1B1 could be used as the basis for a strategy for the detection of androgens and antiandrogens.	tta	41-44	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	52-59
12831835-9	2003	Thus, the differential expression of the tTA-driven hCYP1B1 gene in the transgenic mice was caused by androgen, and it is possible that castrated male and adult female mice expressing the tTA-controlled hCYP1B1 could be used as the basis for a strategy for the detection of androgens and antiandrogens.	tta	41-44	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	203-210
32558605-11	2021	Severe post-operative neuralgia (VAS 7-10) was also significantly more frequent in the TTA group (22.4% vs 2.6% X2 7.07 p 0.0078).Conclusions: MIRA is a safe and effective technique to obtain adequate TDH decompression and is associated with lower morbidity compared to TTA.	tta	87-90	L-threonine dehydrogenase (pseudogene)	Homo sapiens	201-204
9207017-3	1997	By reducing the VP16 moiety of the previously described tTA to 12 amino acids, potential targets for interactions with various cellular transcription factors were eliminated, as were potential epitopes which may elicit a cellular immune response.	tta	56-59	host cell factor C1	Homo sapiens	16-20
35592033-0	2022	Cell Type-Specific Genetic Manipulation and Impaired Circadian Rhythms in Vip tTA Knock-In Mice.	tta	78-81	vasoactive intestinal polypeptide	Mus musculus	74-77
30999573-1	2019	Visible-light-driven photocatalytic supramolecular enantiodifferentiating dimerization of 2-anthracenecarboxylic acid (AC) through triplet-triplet annihilation (TTA), mediated by the Schiff base Pt(II) complex (Pt-1, Pt-2, and Pt-3) was studied.	tta	161-164	zinc finger protein 77	Homo sapiens	211-215
30999573-1	2019	Visible-light-driven photocatalytic supramolecular enantiodifferentiating dimerization of 2-anthracenecarboxylic acid (AC) through triplet-triplet annihilation (TTA), mediated by the Schiff base Pt(II) complex (Pt-1, Pt-2, and Pt-3) was studied.	tta	161-164	zinc finger protein 135	Homo sapiens	227-231
30155047-4	2016	The EL characteristics of DPASP-doped CBP-based devices at various doping concentrations (0-5%) suggest that the dopant DPASP is responsible for the TTA-type delayed fluorescence in the device; no delayed fluorescence was observed for the device using CBP as the host emitter.	tta	149-152	CREB binding protein	Homo sapiens	38-41
29807909-4	2018	tTA activates hTDP-43, which is placed downstream of the tetracycline response element.	tta	0-3	TAR DNA binding protein	Homo sapiens	14-21
29807909-15	2018	Here, we report on a mouse model that overexpresses human TDP-43 using tTA and attempt to recapitulate features of TDP-43 pathology present in human FTLD.	tta	71-74	TAR DNA binding protein	Homo sapiens	58-64
27387268-1	2016	A system demonstrating Nitric Oxide (NO) activated Triplet-Triplet Annihilation (TTA) upconversion has been devised, based on a substituted [Ru(II)(bpy)3](PF6)2 complex (bpy = 2,2"-dipyridine) bearing a single 1,2-diaminophenyl moiety as an NO activatable triplet photosensitizer (Ru-1), and 9,10-diphenylanthracene (DPA) as a triplet acceptor/emitter.	tta	81-84	sperm associated antigen 17	Homo sapiens	155-158
27387268-1	2016	A system demonstrating Nitric Oxide (NO) activated Triplet-Triplet Annihilation (TTA) upconversion has been devised, based on a substituted [Ru(II)(bpy)3](PF6)2 complex (bpy = 2,2"-dipyridine) bearing a single 1,2-diaminophenyl moiety as an NO activatable triplet photosensitizer (Ru-1), and 9,10-diphenylanthracene (DPA) as a triplet acceptor/emitter.	tta	81-84	Scm like with four mbt domains 1	Homo sapiens	281-285
27387268-7	2016	The energy level of the charge transfer state (CTS) for Ru-1 was also obtained electrochemically, supporting the PET mechanism of triplet state quenching and hence the lack of TTA upconversion with Ru-1.	tta	176-179	Scm like with four mbt domains 1	Homo sapiens	56-60
26874397-1	2016	Thio-ether fatty acids (THEFAs), including the parent 2-(tetradecylthio)acetic acid (TTA), are modified fatty acids (FAs) that have profound effects on lipid metabolism given that they are blocked for beta-oxidation, and able to act as peroxisome proliferator-activated receptor (PPAR) agonists.	tta	85-88	peroxisome proliferator activated receptor alpha	Homo sapiens	236-278
26874397-1	2016	Thio-ether fatty acids (THEFAs), including the parent 2-(tetradecylthio)acetic acid (TTA), are modified fatty acids (FAs) that have profound effects on lipid metabolism given that they are blocked for beta-oxidation, and able to act as peroxisome proliferator-activated receptor (PPAR) agonists.	tta	85-88	peroxisome proliferator activated receptor alpha	Homo sapiens	280-284
26146970-4	2015	RESULTS: Patients who controlled their diabetes with insulin (with or without other oral agents) were significantly more likely to undergo TTA (adjusted odds ratio [aOR] = 7.63; 95% confidence interval [CI], 1.17-49.97; P = .03) compared with patients who controlled their diabetes through noninsulin medications or by diet.	tta	139-142	insulin	Homo sapiens	53-60
25289022-7	2014	In the absence of tetracycline, the tTA binds tet-O-Cre to drive the expression of Cre, which recombines the loxP sites of the ZEG or ZAP transgene and results in reporter gene expression.	tta	36-39	zinc finger CCCH-type containing, antiviral 1	Homo sapiens	134-137
24967741-1	2014	The tip of a scanning tunneling microscope (STM) can be used to dehydrogenate freely-diffusing tetrathienoanthracene (TTA) molecules on Cu(111), trapping the molecules into metal-coordinated oligomeric structures.	tta	118-121	TOR signaling pathway regulator	Homo sapiens	4-7