PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 31455781-7 2019 However, an appropriate length MTS (MethaneThioSulfonate) cross-linking reagent (MTS14) restricted the activation of TREK-1_A286C channels by repeated application of FFA. methanethiosulfonate 36-56 potassium two pore domain channel subfamily K member 2 Homo sapiens 117-123 23731861-4 2013 Internal dynamics of spin labels and their static conformational distributions have been studied mainly by electron paramagnetic resonance spectroscopy and molecular dynamics simulations, with a large body of results for the most widely applied methanethiosulfonate spin label MTSL. methanethiosulfonate 245-265 spindlin 1 Homo sapiens 21-25 30248959-7 2018 The methane thiosulfonate (MTS) assay revealed that cell proliferation was significantly reduced after transient transfection of miR-331-3p precursor and/or NACC1 siRNA in UC cells. methanethiosulfonate 4-25 microRNA 331 Homo sapiens 129-136 30248959-7 2018 The methane thiosulfonate (MTS) assay revealed that cell proliferation was significantly reduced after transient transfection of miR-331-3p precursor and/or NACC1 siRNA in UC cells. methanethiosulfonate 4-25 nucleus accumbens associated 1 Homo sapiens 157-162 30248959-7 2018 The methane thiosulfonate (MTS) assay revealed that cell proliferation was significantly reduced after transient transfection of miR-331-3p precursor and/or NACC1 siRNA in UC cells. methanethiosulfonate 27-30 microRNA 331 Homo sapiens 129-136 30248959-7 2018 The methane thiosulfonate (MTS) assay revealed that cell proliferation was significantly reduced after transient transfection of miR-331-3p precursor and/or NACC1 siRNA in UC cells. methanethiosulfonate 27-30 nucleus accumbens associated 1 Homo sapiens 157-162 28097912-0 2017 Methanethiosulfonate derivatives as ligands of the STAT3-SH2 domain. methanethiosulfonate 0-20 signal transducer and activator of transcription 3 Homo sapiens 51-56 28097912-1 2017 With the aim to discover new STAT3 direct inhibitors, potentially useful as anticancer agents, a set of methanethiosulfonate drug hybrids were synthesized. methanethiosulfonate 104-124 signal transducer and activator of transcription 3 Homo sapiens 29-34 28097912-4 2017 These results suggest that methanethiosulfonate moiety can be considered a useful scaffold in the preparation of new direct STAT3 inhibitors. methanethiosulfonate 27-47 signal transducer and activator of transcription 3 Homo sapiens 124-129 28235784-5 2017 Here, we studied the accessibility of single cysteines substituted along the pre-TM2 and TM2 helix (residues 327-357) of the P2X7R using as readouts (i) the covalent maleimide fluorescence accessibility of the surface-bound P2X7R and (ii) covalent modulation of macroscopic and single-channel currents using extracellularly and intracellularly applied methanethiosulfonate (MTS) reagents. methanethiosulfonate 352-372 purinergic receptor P2X 7 Homo sapiens 125-130 27214582-5 2016 Here we report a new methanethiosulfonate derivative of a TAM radical that reacts rapidly and selectively with an engineered cysteine residue to generate a TAM containing side chain (TAM1) in high yield. methanethiosulfonate 21-41 stromal interaction molecule 1 Homo sapiens 183-187 26356049-2 2016 PREs are commonly generated using paramagnetic spin labels (SLs) that contain an unpaired electron in the form of a nitroxide radical, with 1-oxyl-2,2,5,5-tetramethyl-2,5-dihydropyrrol-3-ylmethyl methane thiosulfonate (MTSL) being the most popular tag. methanethiosulfonate 219-223 spindlin 1 Homo sapiens 47-51 26324677-2 2015 Using the Xenopus laevis oocyte expression system and two-electrode voltage clamp, we performed cysteine-scanning mutagenesis of several pore-lining residues of connexin 26 (Cx26) hemichannels, followed by chemical modification using a methanethiosulfonate (MTS) reagent, to help identify the position of the gate. methanethiosulfonate 236-256 gap junction protein beta 2 L homeolog Xenopus laevis 161-172 26324677-2 2015 Using the Xenopus laevis oocyte expression system and two-electrode voltage clamp, we performed cysteine-scanning mutagenesis of several pore-lining residues of connexin 26 (Cx26) hemichannels, followed by chemical modification using a methanethiosulfonate (MTS) reagent, to help identify the position of the gate. methanethiosulfonate 236-256 gap junction protein beta 2 L homeolog Xenopus laevis 174-178 26324677-2 2015 Using the Xenopus laevis oocyte expression system and two-electrode voltage clamp, we performed cysteine-scanning mutagenesis of several pore-lining residues of connexin 26 (Cx26) hemichannels, followed by chemical modification using a methanethiosulfonate (MTS) reagent, to help identify the position of the gate. methanethiosulfonate 258-261 gap junction protein beta 2 L homeolog Xenopus laevis 161-172 26324677-2 2015 Using the Xenopus laevis oocyte expression system and two-electrode voltage clamp, we performed cysteine-scanning mutagenesis of several pore-lining residues of connexin 26 (Cx26) hemichannels, followed by chemical modification using a methanethiosulfonate (MTS) reagent, to help identify the position of the gate. methanethiosulfonate 258-261 gap junction protein beta 2 L homeolog Xenopus laevis 174-178 25635140-3 2015 GluN1(F639C)/GluN2A receptors were less inhibited by ethanol than wild-type receptors, and inhibition was restored to wild-type levels following treatment with ethanol-like methanethiosulfonate reagents. methanethiosulfonate 173-193 glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens 0-5 25635140-3 2015 GluN1(F639C)/GluN2A receptors were less inhibited by ethanol than wild-type receptors, and inhibition was restored to wild-type levels following treatment with ethanol-like methanethiosulfonate reagents. methanethiosulfonate 173-193 glutamate ionotropic receptor NMDA type subunit 2A Homo sapiens 13-19 24302985-3 2013 As S4 of the human skeletal muscle voltage-gated sodium channel, hNav1.4, moves in response to depolarization from the resting to the inactivated state, two D4S4 reporters (R2C and R3C, Arg1451Cys and Arg1454Cys, respectively) move from internal to external positions as deduced by reactivity to internally or externally applied sulfhydryl group reagents, methane thiosulfonates (MTS). methanethiosulfonate 356-378 sodium voltage-gated channel alpha subunit 4 Homo sapiens 65-72 24302985-5 2013 Scorpion alpha-toxin binding impedes D4S4 segment movement during inactivation since the modification rates of R3C in hNav1.4 with methanethiosulfonate (CH3SO2SCH2CH2R, where R = -N(CH3)3 (+) trimethylammonium, MTSET) and benzophenone-4-carboxamidocysteine methanethiosulfonate (BPMTS) were slowed ~10-fold in toxin-modified channels. methanethiosulfonate 131-151 sodium voltage-gated channel alpha subunit 4 Homo sapiens 118-125 23731861-4 2013 Internal dynamics of spin labels and their static conformational distributions have been studied mainly by electron paramagnetic resonance spectroscopy and molecular dynamics simulations, with a large body of results for the most widely applied methanethiosulfonate spin label MTSL. methanethiosulfonate 245-265 spindlin 1 Homo sapiens 266-270 23552283-5 2013 Modification of five of these substituted Cys residues (positions 147, 152, 157, 158, and 161) by methanethiosulfonate (MTS) reagents led to reduction of PCFT function. methanethiosulfonate 98-118 solute carrier family 46 member 1 Homo sapiens 154-158 21746847-4 2011 We find that methanethiosulfonate (MTS) reagents irreversibly modify cysteines substituted for TM1 residues K95, Q98, P99, and L102 when applied to the cytoplasmic side of open channels. methanethiosulfonate 13-33 protein phosphatase 1 regulatory subunit 10 Homo sapiens 118-121 23442957-5 2013 Here, we investigated CFTR"s TM1 by applying methanethiosulfonate (MTS) reagents from both cytoplasmic and extracellular sides of the membrane. methanethiosulfonate 45-65 CF transmembrane conductance regulator Homo sapiens 22-26 23442957-5 2013 Here, we investigated CFTR"s TM1 by applying methanethiosulfonate (MTS) reagents from both cytoplasmic and extracellular sides of the membrane. methanethiosulfonate 67-70 CF transmembrane conductance regulator Homo sapiens 22-26 21746847-4 2011 We find that methanethiosulfonate (MTS) reagents irreversibly modify cysteines substituted for TM1 residues K95, Q98, P99, and L102 when applied to the cytoplasmic side of open channels. methanethiosulfonate 35-38 protein phosphatase 1 regulatory subunit 10 Homo sapiens 118-121 21306584-0 2011 Effect of verapamil on the action of methanethiosulfonate reagents on human voltage-gated K(v)1.3 channels: implications for the C-type inactivated state. methanethiosulfonate 37-57 potassium voltage-gated channel subfamily A member 3 Homo sapiens 90-97 20109441-4 2010 We also reported Cys-targeting methanethiosulfonate molecules (AMTSn), which, under conditions that spared human AChE, caused total irreversible inhibition of aphid AChE, 95% inhibition of AChE from the malaria vector mosquito (Anopheles gambia), and >80% inhibition of activity from the yellow fever mosquito (Aedes aegypti) and northern house mosquito (Culex pipiens). methanethiosulfonate 31-51 acetylcholinesterase (Cartwright blood group) Homo sapiens 113-117 21525301-4 2011 We use a thiol-reactive methane thiosulfonate (MTS) reagent to modify a conformationally sensitive cysteine residue to demonstrate that hSERT spends more time in an outward facing conformation when transporting DA than when transporting 5-HT. methanethiosulfonate 24-45 solute carrier family 6 member 4 Homo sapiens 136-141 21525301-4 2011 We use a thiol-reactive methane thiosulfonate (MTS) reagent to modify a conformationally sensitive cysteine residue to demonstrate that hSERT spends more time in an outward facing conformation when transporting DA than when transporting 5-HT. methanethiosulfonate 47-50 solute carrier family 6 member 4 Homo sapiens 136-141 21209359-3 2011 Epitope-tagged AE1 R730C at the Xenopus laevis oocyte surface exhibited severely reduced Cl(-) transport insensitive to rescue by glycophorin A (GPA) coexpression or by methanethiosulfonate (MTS) treatment. methanethiosulfonate 169-189 solute carrier family 4 member 1 (Diego blood group)S homeolog Xenopus laevis 15-18 21209359-3 2011 Epitope-tagged AE1 R730C at the Xenopus laevis oocyte surface exhibited severely reduced Cl(-) transport insensitive to rescue by glycophorin A (GPA) coexpression or by methanethiosulfonate (MTS) treatment. methanethiosulfonate 191-194 solute carrier family 4 member 1 (Diego blood group)S homeolog Xenopus laevis 15-18 20664003-4 2010 To test this hypothesis we have begun to obtain structural information about family B GPCRs, using as a prototype the CRF(1), by determining the ability of sulfhydryl-specific methanethiosulfonate derivatives, such as the methanethiosulfonate-ethylammonium (MTSEA), to react with CRF(1) and thus irreversibly inhibit (125)I-Tyr(0)-sauvagine binding. methanethiosulfonate 176-196 corticotropin releasing hormone receptor 1 Homo sapiens 118-124 20664003-4 2010 To test this hypothesis we have begun to obtain structural information about family B GPCRs, using as a prototype the CRF(1), by determining the ability of sulfhydryl-specific methanethiosulfonate derivatives, such as the methanethiosulfonate-ethylammonium (MTSEA), to react with CRF(1) and thus irreversibly inhibit (125)I-Tyr(0)-sauvagine binding. methanethiosulfonate 176-196 corticotropin releasing hormone receptor 1 Homo sapiens 280-286 20109441-4 2010 We also reported Cys-targeting methanethiosulfonate molecules (AMTSn), which, under conditions that spared human AChE, caused total irreversible inhibition of aphid AChE, 95% inhibition of AChE from the malaria vector mosquito (Anopheles gambia), and >80% inhibition of activity from the yellow fever mosquito (Aedes aegypti) and northern house mosquito (Culex pipiens). methanethiosulfonate 31-51 acetylcholinesterase (Cartwright blood group) Homo sapiens 165-169 20109441-4 2010 We also reported Cys-targeting methanethiosulfonate molecules (AMTSn), which, under conditions that spared human AChE, caused total irreversible inhibition of aphid AChE, 95% inhibition of AChE from the malaria vector mosquito (Anopheles gambia), and >80% inhibition of activity from the yellow fever mosquito (Aedes aegypti) and northern house mosquito (Culex pipiens). methanethiosulfonate 31-51 acetylcholinesterase (Cartwright blood group) Homo sapiens 165-169 19714254-8 2009 Herein, we report that, under conditions that spare the human AChE, a methanethiosulfonate-containing molecule at 6 microM irreversibly inhibited 95% of the AChE activity extracted from An. methanethiosulfonate 70-90 acetylcholinesterase (Cartwright blood group) Homo sapiens 62-66 19714254-8 2009 Herein, we report that, under conditions that spare the human AChE, a methanethiosulfonate-containing molecule at 6 microM irreversibly inhibited 95% of the AChE activity extracted from An. methanethiosulfonate 70-90 acetylcholinesterase (Cartwright blood group) Homo sapiens 157-161 19714254-11 2009 This type of inhibition is fast ( approximately 30 min) and due to conjugation of the inhibitor to the active-site Cys of mosquito AP-AChE, according to our observed reactivation of the methanethiosulfonate-inhibited AChE by 2-mercaptoethanol. methanethiosulfonate 186-206 acetylcholinesterase (Cartwright blood group) Homo sapiens 134-138 19714254-11 2009 This type of inhibition is fast ( approximately 30 min) and due to conjugation of the inhibitor to the active-site Cys of mosquito AP-AChE, according to our observed reactivation of the methanethiosulfonate-inhibited AChE by 2-mercaptoethanol. methanethiosulfonate 186-206 acetylcholinesterase (Cartwright blood group) Homo sapiens 217-221 19456123-7 2009 Treatment of CP12 with a methane thiosulfonate derivative spin-label (MTSL) led to the labeling of the cysteine residues involved in the C-terminal bridge only as revealed by mass spectrometry. methanethiosulfonate 25-46 uncharacterized protein Chlamydomonas reinhardtii 13-17 18272676-6 2008 Moreover, M3c residues at or below A651(NR2B, A7 in SYTANLAAF) react with external methanethiosulfonate (MTS) reagents approximately 500 to 1000-fold faster in the presence than in the absence of agonists NMDA and glycine. methanethiosulfonate 83-103 glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens 40-44 19538299-3 2009 Using stable transfected Madin Darby canine kidney type I cells, induced to express claudin-2, we show that paracellular cation transport can be blocked by sulfhydryl-specific methanethiosulfonate (MTS) and that SCAM can be used to identify residues that line paracellular pores. methanethiosulfonate 198-201 claudin 2 Canis lupus familiaris 84-93 18628241-6 2008 Cysteine mutants at those positions confirmed the accessibility of hSERT/F556 to different methanethiosulfonate (MTS) reagents, suggesting its presence in a hydrophilic environment of the protein. methanethiosulfonate 91-111 solute carrier family 6 member 4 Homo sapiens 67-72 18311924-1 2008 We report the involvement of transmembrane domain 4 (TM4) of hASBT in forming the putative translocation pathway, using cysteine-scanning mutagenesis in conjunction with solvent-accessibility studies using the membrane-impermeant, sulfhydryl-specific methanethiosulfonate reagents. methanethiosulfonate 251-271 solute carrier family 10 member 2 Homo sapiens 61-66 19381710-3 2009 We have combined SCAM with investigation of the charge-dependent effects of methanethiosulfonate (MTS) reagents on the functional permeation properties of cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channels. methanethiosulfonate 76-96 CF transmembrane conductance regulator Homo sapiens 155-206 19381710-3 2009 We have combined SCAM with investigation of the charge-dependent effects of methanethiosulfonate (MTS) reagents on the functional permeation properties of cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channels. methanethiosulfonate 76-96 CF transmembrane conductance regulator Homo sapiens 208-212 19381710-3 2009 We have combined SCAM with investigation of the charge-dependent effects of methanethiosulfonate (MTS) reagents on the functional permeation properties of cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channels. methanethiosulfonate 98-101 CF transmembrane conductance regulator Homo sapiens 155-206 19381710-3 2009 We have combined SCAM with investigation of the charge-dependent effects of methanethiosulfonate (MTS) reagents on the functional permeation properties of cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channels. methanethiosulfonate 98-101 CF transmembrane conductance regulator Homo sapiens 208-212 19194505-6 2009 Herein we report the development of a methanethiosulfonate-containing small molecule that, at 6.0 microM, irreversibly inhibits 99% of all AChE activity extracted from the greenbug aphid (Schizaphis graminum) without any measurable inhibition of the human AChE. methanethiosulfonate 38-58 acetylcholinesterase (Cartwright blood group) Homo sapiens 139-143 19194505-6 2009 Herein we report the development of a methanethiosulfonate-containing small molecule that, at 6.0 microM, irreversibly inhibits 99% of all AChE activity extracted from the greenbug aphid (Schizaphis graminum) without any measurable inhibition of the human AChE. methanethiosulfonate 38-58 acetylcholinesterase (Cartwright blood group) Homo sapiens 256-260 18487206-0 2008 Cysteine substitution mutagenesis and the effects of methanethiosulfonate reagents at P2X2 and P2X4 receptors support a core common mode of ATP action at P2X receptors. methanethiosulfonate 53-73 purinergic receptor P2X 2 Homo sapiens 86-90 18272676-6 2008 Moreover, M3c residues at or below A651(NR2B, A7 in SYTANLAAF) react with external methanethiosulfonate (MTS) reagents approximately 500 to 1000-fold faster in the presence than in the absence of agonists NMDA and glycine. methanethiosulfonate 105-108 glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens 40-44 14522974-0 2003 Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites. methanethiosulfonate 0-20 ATP binding cassette subfamily B member 1 Homo sapiens 75-89 17428985-3 2007 We used cysteine-scanning mutagenesis, radiolabeled 2-azido ATP binding, and methanethiosulfonate (MTS) compounds to identify amino acid residues involved in ATP binding and gating of the human P2X1 receptor. methanethiosulfonate 77-97 purinergic receptor P2X 1 Homo sapiens 194-207 17428985-3 2007 We used cysteine-scanning mutagenesis, radiolabeled 2-azido ATP binding, and methanethiosulfonate (MTS) compounds to identify amino acid residues involved in ATP binding and gating of the human P2X1 receptor. methanethiosulfonate 99-102 purinergic receptor P2X 1 Homo sapiens 194-207 16092934-4 2005 hNET and the mutants were also resistant to methanethiosulfonate (MTS), ethylammonium (MTSEA) and MTStrimethylammonium (MTSET). methanethiosulfonate 44-64 solute carrier family 6 member 2 Homo sapiens 0-4 16092934-4 2005 hNET and the mutants were also resistant to methanethiosulfonate (MTS), ethylammonium (MTSEA) and MTStrimethylammonium (MTSET). methanethiosulfonate 66-69 solute carrier family 6 member 2 Homo sapiens 0-4 16891366-2 2006 Cytoplasmic-side methanethiosulfonate (MTS) reagents blocked K(+) permeation in native Kir1.1 channels, expressed in Xenopus oocytes. methanethiosulfonate 17-37 potassium inwardly rectifying channel subfamily J member 1 S homeolog Xenopus laevis 87-93 16891366-2 2006 Cytoplasmic-side methanethiosulfonate (MTS) reagents blocked K(+) permeation in native Kir1.1 channels, expressed in Xenopus oocytes. methanethiosulfonate 39-42 potassium inwardly rectifying channel subfamily J member 1 S homeolog Xenopus laevis 87-93 16631150-4 2006 It is shown that the spectral peaks assigned to the methyl head groups of phosphatidylcholine and sphingomyelin in the (1)H spectra of LDL exhibit line broadening when otherwise free thiol groups of apoB are covalently modified by methanethiosulfonate spin label. methanethiosulfonate 231-251 apolipoprotein B Homo sapiens 199-203 16584200-1 2006 Using cysteine mutagenesis and chemical modification by methanethiosulfonate derivatives, it was demonstrated that the external putative loop, joining transmembrane segments (TM"s) IV-V of rabbit Na+/glucose cotransporter, rSGLT1, forms part of a Na+ binding and voltage sensing domain. methanethiosulfonate 56-76 solute carrier family 5 member 1 Rattus norvegicus 223-229 15840841-1 2005 In this study, the sensitivity of the CB2 receptor to methanethiosulfonate (MTS) derivatives was tested, and a native cysteine residue conferring the sensitivity was identified. methanethiosulfonate 54-74 cannabinoid receptor 2 Homo sapiens 38-41 15840841-1 2005 In this study, the sensitivity of the CB2 receptor to methanethiosulfonate (MTS) derivatives was tested, and a native cysteine residue conferring the sensitivity was identified. methanethiosulfonate 76-79 cannabinoid receptor 2 Homo sapiens 38-41 14609334-3 2003 To apply this approach to the C2 domain of cytosolic phospholipase A(2) (cPLA(2)), single cysteines were introduced at all 27 positions in the three Ca(2+)-binding loops and labeled with a methanethiosulfonate spin-label. methanethiosulfonate 189-209 phospholipase A2 group IVA Homo sapiens 43-80 12963712-0 2003 Methanethiosulfonate ethylammonium block of amine currents through the ryanodine receptor reveals single pore architecture. methanethiosulfonate 0-20 ryanodine receptor 1 Homo sapiens 71-89 11004203-4 2000 The double-barrel model proposed for ClC-0 was recently challenged by a one-pore model partly based on experiments with ClC-1 exploiting cysteine mutagenesis followed by modification with methanethiosulfonate (MTS) reagents. methanethiosulfonate 210-213 chloride voltage-gated channel 1 Homo sapiens 120-125 12879165-0 2003 Methanethiosulfonate-modification alters local anesthetic block in rNav1.4 cysteine-substituted mutants S1276C and L1280C. methanethiosulfonate 0-20 neuron navigator 1 Rattus norvegicus 67-72 11395483-1 2001 The binding affinity of the cocaine analog [(3)H]2 beta-carbomethoxy-3beta-(4-fluorophenyl) tropane (WIN) for the dopamine transporter (DAT) is increased by the reaction of Cys-90, at the extracellular end of the first transmembrane segment, with methanethiosulfonate (MTS) reagents. methanethiosulfonate 247-267 solute carrier family 6 member 3 Homo sapiens 114-134 11395483-1 2001 The binding affinity of the cocaine analog [(3)H]2 beta-carbomethoxy-3beta-(4-fluorophenyl) tropane (WIN) for the dopamine transporter (DAT) is increased by the reaction of Cys-90, at the extracellular end of the first transmembrane segment, with methanethiosulfonate (MTS) reagents. methanethiosulfonate 247-267 solute carrier family 6 member 3 Homo sapiens 136-139 11279063-0 2001 Defining the drug-binding site in the human multidrug resistance P-glycoprotein using a methanethiosulfonate analog of verapamil, MTS-verapamil. methanethiosulfonate 88-108 ATP binding cassette subfamily B member 1 Homo sapiens 65-79 12885876-0 2003 Probing the pore of ClC-0 by substituted cysteine accessibility method using methane thiosulfonate reagents. methanethiosulfonate 77-98 Charcot-Leyden crystal galectin Homo sapiens 20-23 11986364-5 2002 To investigate this mechanism, we used the membrane-impermeable methanethiosulfonates, MTSET and MTS-TEAH, to modify Kir6.2 channels. methanethiosulfonate 64-85 potassium inwardly rectifying channel subfamily J member 11 Homo sapiens 117-123 11790775-1 2002 Intracellular application of certain charged methanethiosulfonate (MTS) reagents modified and irreversibly inhibited Kir6.2 channels when cysteine substitutions were introduced at positions Ile-210, Ile-211, or Ser-212 within the putative cytoplasmic region. methanethiosulfonate 45-65 potassium inwardly rectifying channel subfamily J member 11 Homo sapiens 117-123 11054653-2 2000 A methanethiosulfonate spin label was used to probe the free cysteine residues of apoB with electron paramagnetic resonance (EPR) spectroscopy. methanethiosulfonate 2-22 apolipoprotein B Homo sapiens 82-86 9062118-8 1997 The cysteine-specific spin-label, methanethiosulfonate spin-label (MTSSL), was attached to yeast iso-1-cytochrome c at the single naturally occurring cysteine102, and the emphasis for this work was on this disulfide-attached spin-labeled prototype. methanethiosulfonate 34-54 threonine ammonia-lyase ILV1 Saccharomyces cerevisiae S288C 97-102 10423365-2 1999 The peptide, which follows the single letter sequence, was reacted with the methanethiosulfonate spin label at the cysteine sulfur. methanethiosulfonate 76-96 spindlin 1 Homo sapiens 97-101 10824857-1 1999 A cysteine-specific methanethiosulfonate spin label was introduced into yeast iso-1-cytochrome c at three different positions. methanethiosulfonate 20-40 threonine ammonia-lyase ILV1 Saccharomyces cerevisiae S288C 78-83 9689064-2 1998 Binding of the cocaine analog, [3H]2-beta-carbomethoxy-3-beta-(4-fluorophenyl) tropane (CFT) to the dopamine transporter is sensitive to polar sulfhydryl-specific derivatives of methanethiosulfonate (MTS). methanethiosulfonate 178-198 solute carrier family 6 member 3 Homo sapiens 100-120 9689064-2 1998 Binding of the cocaine analog, [3H]2-beta-carbomethoxy-3-beta-(4-fluorophenyl) tropane (CFT) to the dopamine transporter is sensitive to polar sulfhydryl-specific derivatives of methanethiosulfonate (MTS). methanethiosulfonate 200-203 solute carrier family 6 member 3 Homo sapiens 100-120 9041453-0 1997 Methanethiosulfonate derivatives inhibit current through the ryanodine receptor/channel. methanethiosulfonate 0-20 ryanodine receptor 1 Homo sapiens 61-79 1667623-0 1991 Improved method for measurement of rhodanese activity using methanethiosulfonate as sulfur donor substrate and its application to human serum. methanethiosulfonate 60-80 thiosulfate sulfurtransferase Bos taurus 35-44 1667623-1 1991 We have developed a sensitive method for the measurement of rhodanese activity in human serum which is based on the colorimetric method for the determination of thiocyanate produced from methanethiosulfonate and cyanide as substrates. methanethiosulfonate 187-207 thiosulfate sulfurtransferase Bos taurus 60-69 34776648-2 2021 Methanethiosulfonate spin label (MTSSL), has become ubiquitous in the SDSL of proteins, however, has limitations owing to its high number of rotamers, and reducibility. methanethiosulfonate 0-20 spindlin 1 Homo sapiens 21-25 32472188-4 2021 We found that alpha5-containing nAChRs are irreversibly blocked by methanethiosulfonate (MTS) reagents through a covalent reaction with a cysteine present only in alpha5. methanethiosulfonate 67-87 immunoglobulin kappa variable 2D-26 Homo sapiens 14-20 32472188-4 2021 We found that alpha5-containing nAChRs are irreversibly blocked by methanethiosulfonate (MTS) reagents through a covalent reaction with a cysteine present only in alpha5. methanethiosulfonate 67-87 immunoglobulin kappa variable 2D-26 Homo sapiens 163-169 32472188-4 2021 We found that alpha5-containing nAChRs are irreversibly blocked by methanethiosulfonate (MTS) reagents through a covalent reaction with a cysteine present only in alpha5. methanethiosulfonate 89-92 immunoglobulin kappa variable 2D-26 Homo sapiens 14-20 32472188-4 2021 We found that alpha5-containing nAChRs are irreversibly blocked by methanethiosulfonate (MTS) reagents through a covalent reaction with a cysteine present only in alpha5. methanethiosulfonate 89-92 immunoglobulin kappa variable 2D-26 Homo sapiens 163-169