PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
18685225-0	2008	Arabidopsis CYP85A2 catalyzes lactonization reactions in the biosynthesis of 2-deoxy-7-oxalactone brassinosteroids.	Brassinosteroids	98-114	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	12-19
19704566-1	2008	BAK1 and BKK1 are two functionally redundant leucine-rich repeat receptor-like protein kinases (LRR-RLKs) involved in brassinosteroid signal transduction by their direct interactions with the BR receptor, BRI1.	Brassinosteroids	118-133	BCL2 antagonist/killer 1	Homo sapiens	0-4
18694562-0	2008	Sequential transphosphorylation of the BRI1/BAK1 receptor kinase complex impacts early events in brassinosteroid signaling.	Brassinosteroids	97-112	BCL2 antagonist/killer 1	Homo sapiens	44-48
18694562-1	2008	Brassinosteroids (BRs) regulate plant development through a signal transduction pathway involving the BRI1 and BAK1 transmembrane receptor kinases.	Brassinosteroids	0-16	BCL2 antagonist/killer 1	Homo sapiens	111-115
18694562-1	2008	Brassinosteroids (BRs) regulate plant development through a signal transduction pathway involving the BRI1 and BAK1 transmembrane receptor kinases.	Brassinosteroids	18-21	BCL2 antagonist/killer 1	Homo sapiens	111-115
18694562-3	2008	We demonstrate that BR-dependent activation of BRI1 precedes association with BAK1 in planta, and that BRI1 positively regulates BAK1 phosphorylation levels in vivo.	Brassinosteroids	20-22	BCL2 antagonist/killer 1	Homo sapiens	78-82
18653891-1	2008	Brassinosteroids (BRs) bind to the extracellular domain of the receptor kinase BRI1 to activate a signal transduction cascade that regulates nuclear gene expression and plant development.	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	79-83
18653891-1	2008	Brassinosteroids (BRs) bind to the extracellular domain of the receptor kinase BRI1 to activate a signal transduction cascade that regulates nuclear gene expression and plant development.	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	79-83
18621007-6	2008	It also impedes BAK1-dependent host immune responses to diverse other MAMPs and brassinosteroid signaling.	Brassinosteroids	80-95	BRI1-associated receptor kinase	Arabidopsis thaliana	16-20
18599455-7	2008	arf2 mutants are less sensitive to changes in endogenous BR levels, whereas a large proportion of genes affected in an arf2 background are returned to near wild-type levels by altering BR biosynthesis.	Brassinosteroids	57-59	ADP ribosylation factor 4	Homo sapiens	0-4
18599455-7	2008	arf2 mutants are less sensitive to changes in endogenous BR levels, whereas a large proportion of genes affected in an arf2 background are returned to near wild-type levels by altering BR biosynthesis.	Brassinosteroids	185-187	ADP ribosylation factor 4	Homo sapiens	119-123
18236008-1	2008	Squalene synthase (SQS) catalyzes the condensation of two molecules of farnesyl diphosphate (FPP) to produce squalene (SQ), the first committed precursor for sterol, brassinosteroid, and triterpene biosynthesis.	Brassinosteroids	166-181	squalene synthase 1	Arabidopsis thaliana	0-17
18467490-2	2008	BRs signal through a cell surface receptor kinase, BRI1, and a GSK3-like kinase, BIN2, to regulate the BES1/BZR1 family of transcription factors, which directly bind to target gene promoters to activate or repress gene expression and mediate BR responses.	Brassinosteroids	0-3	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	51-55
18467490-2	2008	BRs signal through a cell surface receptor kinase, BRI1, and a GSK3-like kinase, BIN2, to regulate the BES1/BZR1 family of transcription factors, which directly bind to target gene promoters to activate or repress gene expression and mediate BR responses.	Brassinosteroids	0-3	Protein kinase superfamily protein	Arabidopsis thaliana	81-85
18467490-2	2008	BRs signal through a cell surface receptor kinase, BRI1, and a GSK3-like kinase, BIN2, to regulate the BES1/BZR1 family of transcription factors, which directly bind to target gene promoters to activate or repress gene expression and mediate BR responses.	Brassinosteroids	0-3	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	103-107
18499742-0	2008	Loss-of-function mutations in the Arabidopsis heterotrimeric G-protein alpha subunit enhance the developmental defects of brassinosteroid signaling and biosynthesis mutants.	Brassinosteroids	122-137	G protein alpha subunit 1	Arabidopsis thaliana	61-84
18499742-2	2008	Previous studies indicated that GPA1 is involved in brassinosteroid (BR) response.	Brassinosteroids	52-67	G protein alpha subunit 1	Arabidopsis thaliana	32-36
18499742-2	2008	Previous studies indicated that GPA1 is involved in brassinosteroid (BR) response.	Brassinosteroids	69-71	G protein alpha subunit 1	Arabidopsis thaliana	32-36
18499742-3	2008	Here we provide genetic evidence that loss-of-function mutations in GPA1, gpa1-2 and gpa1-4, enhance the developmental defects of bri1-5, a weak allele of a BR receptor mutant, and det2-1, a BR-deficient mutant in Arabidopsis.	Brassinosteroids	157-159	G protein alpha subunit 1	Arabidopsis thaliana	68-72
18499742-3	2008	Here we provide genetic evidence that loss-of-function mutations in GPA1, gpa1-2 and gpa1-4, enhance the developmental defects of bri1-5, a weak allele of a BR receptor mutant, and det2-1, a BR-deficient mutant in Arabidopsis.	Brassinosteroids	157-159	G protein alpha subunit 1	Arabidopsis thaliana	74-80
18499742-3	2008	Here we provide genetic evidence that loss-of-function mutations in GPA1, gpa1-2 and gpa1-4, enhance the developmental defects of bri1-5, a weak allele of a BR receptor mutant, and det2-1, a BR-deficient mutant in Arabidopsis.	Brassinosteroids	157-159	G protein alpha subunit 1	Arabidopsis thaliana	85-91
18726001-2	2008	BIN2 is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling.	Brassinosteroids	66-81	Protein kinase superfamily protein	Arabidopsis thaliana	0-4
18182375-2	2008	In Arabidopsis, the steroid hormone (brassinosteroid (BR)) binds to the extracellular domain of a receptor kinase (BRI1) to initiate a phosphorylation/dephosphorylation cascade that controls gene expression and plant growth.	Brassinosteroids	37-52	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	115-119
18726001-3	2008	Genetic studies suggested that BIN2 is inhibited in response to BR perception at the cell surface to relieve its inhibitory effects on downstream targets; however, little is known about biochemical mechanisms of its inhibition.	Brassinosteroids	64-66	Protein kinase superfamily protein	Arabidopsis thaliana	31-35
18726001-5	2008	Exogenous application of a BR biosynthesis inhibitor and an active BR increased and decreased the amount of BIN2 proteins, respectively.	Brassinosteroids	27-29	Protein kinase superfamily protein	Arabidopsis thaliana	108-112
18726001-7	2008	Exogenous application of different plant growth hormones revealed that BIN2 depletion is specifically induced by BR through a functional BR receptor, while treatment of a proteasome inhibitor, MG132, not only prevented the BR-induced BIN2 depletion but also nullified the inhibitory effect of BR on the BIN2 kinase activity.	Brassinosteroids	113-115	Protein kinase superfamily protein	Arabidopsis thaliana	71-75
18726001-7	2008	Exogenous application of different plant growth hormones revealed that BIN2 depletion is specifically induced by BR through a functional BR receptor, while treatment of a proteasome inhibitor, MG132, not only prevented the BR-induced BIN2 depletion but also nullified the inhibitory effect of BR on the BIN2 kinase activity.	Brassinosteroids	137-139	Protein kinase superfamily protein	Arabidopsis thaliana	71-75
19704727-0	2008	Brassinosteroid-independent functions of the BRI1-associated kinase BAK1/SERK3.	Brassinosteroids	0-15	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	45-49
19704727-0	2008	Brassinosteroid-independent functions of the BRI1-associated kinase BAK1/SERK3.	Brassinosteroids	0-15	BRI1-associated receptor kinase	Arabidopsis thaliana	68-72
18175930-0	2008	Brz220 interacts with DWF4, a cytochrome P450 monooxygenase in brassinosteroid biosynthesis, and exerts biological activity.	Brassinosteroids	63-78	Cytochrome P450 superfamily protein	Arabidopsis thaliana	22-26
18175930-0	2008	Brz220 interacts with DWF4, a cytochrome P450 monooxygenase in brassinosteroid biosynthesis, and exerts biological activity.	Brassinosteroids	63-78	Cytochrome P450 superfamily protein	Arabidopsis thaliana	30-59
18453531-6	2008	In rice, the orthologues of SVP and AGL24 are OsMADS22, OsMADS47, and OsMADS55 and these three genes are involved in the negative regulation of brassinosteroid responses.	Brassinosteroids	144-159	K-box region and MADS-box transcription factor family protein	Arabidopsis thaliana	28-31
18453531-6	2008	In rice, the orthologues of SVP and AGL24 are OsMADS22, OsMADS47, and OsMADS55 and these three genes are involved in the negative regulation of brassinosteroid responses.	Brassinosteroids	144-159	AGAMOUS-like 24	Arabidopsis thaliana	36-41
19704727-0	2008	Brassinosteroid-independent functions of the BRI1-associated kinase BAK1/SERK3.	Brassinosteroids	0-15	BRI1-associated receptor kinase	Arabidopsis thaliana	73-78
18054220-2	2008	We have reported that the synthetic brassinosteroid (22S,23S)-3beta-bromo-5alpha,22,23-trihydroxystigmastan-6-one, designated as 2, is a potent antiviral in vitro and reduces the incidence of murine herpetic stromal keratitis, although it does not exert an antiviral effect in vivo.	Brassinosteroids	36-51	arylsulfatase A	Mus musculus	126-130
18045813-8	2008	The TDE1 gene was found to be identical to the DE-ETIOLATED 2 gene known to be involved in brassinosteroid (BR) biosynthesis, and the tde1 probacula-defective phenotypes were recovered in the presence of BR application.	Brassinosteroids	91-106	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	47-61
18045813-8	2008	The TDE1 gene was found to be identical to the DE-ETIOLATED 2 gene known to be involved in brassinosteroid (BR) biosynthesis, and the tde1 probacula-defective phenotypes were recovered in the presence of BR application.	Brassinosteroids	108-110	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	47-61
18045813-8	2008	The TDE1 gene was found to be identical to the DE-ETIOLATED 2 gene known to be involved in brassinosteroid (BR) biosynthesis, and the tde1 probacula-defective phenotypes were recovered in the presence of BR application.	Brassinosteroids	204-206	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	47-61
19704770-1	2008	Brassinosteroids (BRs) are perceived by Brassinosteroid Insensitive 1 (BRI1), that encodes a leucine-rich repeat receptor kinase.	Brassinosteroids	0-16	brassinosteroid LRR receptor kinase	Solanum lycopersicum	71-75
18596112-6	2008	Gibberellin induced expression of GhTUB1 and GhTUB3, ethylene induced expression of GhTUB5, GhTUB9, and GhTUB12, brassinosteroids induced expression of GhTUB1, GhTUB3, GhTUB9, and GhTUB12, and lignoceric acid induced expression of GhTUB1, GhTUB3, and GhTUB12.	Brassinosteroids	113-129	tubulin beta-9 chain	Gossypium hirsutum	34-40
18596112-6	2008	Gibberellin induced expression of GhTUB1 and GhTUB3, ethylene induced expression of GhTUB5, GhTUB9, and GhTUB12, brassinosteroids induced expression of GhTUB1, GhTUB3, GhTUB9, and GhTUB12, and lignoceric acid induced expression of GhTUB1, GhTUB3, and GhTUB12.	Brassinosteroids	113-129	tubulin beta-9 chain	Gossypium hirsutum	104-110
18596112-6	2008	Gibberellin induced expression of GhTUB1 and GhTUB3, ethylene induced expression of GhTUB5, GhTUB9, and GhTUB12, brassinosteroids induced expression of GhTUB1, GhTUB3, GhTUB9, and GhTUB12, and lignoceric acid induced expression of GhTUB1, GhTUB3, and GhTUB12.	Brassinosteroids	113-129	tubulin beta-9 chain	Gossypium hirsutum	104-110
19704770-1	2008	Brassinosteroids (BRs) are perceived by Brassinosteroid Insensitive 1 (BRI1), that encodes a leucine-rich repeat receptor kinase.	Brassinosteroids	18-21	brassinosteroid LRR receptor kinase	Solanum lycopersicum	71-75
19704770-1	2008	Brassinosteroids (BRs) are perceived by Brassinosteroid Insensitive 1 (BRI1), that encodes a leucine-rich repeat receptor kinase.	Brassinosteroids	0-15	brassinosteroid LRR receptor kinase	Solanum lycopersicum	71-75
17588517-5	2007	We demonstrated that bri1-9 is retained in the ER through interactions with several ER chaperones and that ebs1 mutations significantly reduce the stringency of the retention-based ER quality control, allowing export of the structurally imperfect yet biochemically competent bri1-9 to the cell surface for BR perception.	Brassinosteroids	306-308	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	21-27
17905899-5	2007	Compared with the wild type, the null mutant siz1-3 is smaller in stature because of reduced expression of genes involved in brassinosteroid biosynthesis and signaling.	Brassinosteroids	125-140	DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain-containing protein	Arabidopsis thaliana	45-49
17681126-1	2007	Brassinosteroid (BR) signaling requires the BIN2 kinase-promoted interaction of 14-3-3 proteins with the transcriptional regulators BZR1 and BZR2, which are subsequently redistributed to the cytoplasm by BRs.	Brassinosteroids	0-15	bridging integrator 2	Homo sapiens	44-48
17681126-1	2007	Brassinosteroid (BR) signaling requires the BIN2 kinase-promoted interaction of 14-3-3 proteins with the transcriptional regulators BZR1 and BZR2, which are subsequently redistributed to the cytoplasm by BRs.	Brassinosteroids	17-19	bridging integrator 2	Homo sapiens	44-48
17681130-3	2007	How BR-regulated phosphorylation controls the activities of BZR1/BZR2 is not fully understood.	Brassinosteroids	4-6	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	60-64
17681130-3	2007	How BR-regulated phosphorylation controls the activities of BZR1/BZR2 is not fully understood.	Brassinosteroids	4-6	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	65-69
17565582-2	2007	DET2, an Arabidopsis steroid 5d-reductase, is considered to catalyze a major rate-limiting in brassinosteroid (BR) biosynthesis.	Brassinosteroids	94-109	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	0-4
17565582-2	2007	DET2, an Arabidopsis steroid 5d-reductase, is considered to catalyze a major rate-limiting in brassinosteroid (BR) biosynthesis.	Brassinosteroids	111-113	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	0-4
17848588-5	2007	Analyses of the BR-insensitive mutant bri1-116 and BR-hypersensitive mutant bzr1-1D identified five proteins (PATL1, PATL2, THI1, AtMDAR3, and NADP-ME2) affected both by BR treatment and in the mutants, suggesting their importance in BR action.	Brassinosteroids	51-53	PATELLIN 1	Arabidopsis thaliana	110-115
17848588-5	2007	Analyses of the BR-insensitive mutant bri1-116 and BR-hypersensitive mutant bzr1-1D identified five proteins (PATL1, PATL2, THI1, AtMDAR3, and NADP-ME2) affected both by BR treatment and in the mutants, suggesting their importance in BR action.	Brassinosteroids	51-53	PATELLIN 2	Arabidopsis thaliana	117-122
17848588-5	2007	Analyses of the BR-insensitive mutant bri1-116 and BR-hypersensitive mutant bzr1-1D identified five proteins (PATL1, PATL2, THI1, AtMDAR3, and NADP-ME2) affected both by BR treatment and in the mutants, suggesting their importance in BR action.	Brassinosteroids	51-53	thiazole biosynthetic enzyme, chloroplast (ARA6) (THI1) (THI4)	Arabidopsis thaliana	124-128
17848588-5	2007	Analyses of the BR-insensitive mutant bri1-116 and BR-hypersensitive mutant bzr1-1D identified five proteins (PATL1, PATL2, THI1, AtMDAR3, and NADP-ME2) affected both by BR treatment and in the mutants, suggesting their importance in BR action.	Brassinosteroids	51-53	NADP-malic enzyme 2	Arabidopsis thaliana	143-151
17873094-0	2007	Nucleocytoplasmic shuttling of BZR1 mediated by phosphorylation is essential in Arabidopsis brassinosteroid signaling.	Brassinosteroids	92-107	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	31-35
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	0-2	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	85-89
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	110-133
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	135-139
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	0-2	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	193-197
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	0-2	Protein kinase superfamily protein	Arabidopsis thaliana	255-283
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	0-2	Protein kinase superfamily protein	Arabidopsis thaliana	285-289
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	164-179	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	85-89
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	164-179	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	110-133
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	164-179	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	135-139
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	164-179	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	193-197
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	164-179	Protein kinase superfamily protein	Arabidopsis thaliana	255-283
17873094-2	2007	BR acts by modulating the phosphorylation status of two key transcriptional factors, BRI1 EMS SUPPRESSOR1 and BRASSINAZOLE RESISTANT1 (BZR1), through the action of BRASSINOSTEROID INSENSITIVE1/BRI1 ASSOCIATED RECEPTOR KINASE1 receptors and a GSK3 kinase, BRASSINOSTEROID INSENSITIVE2 (BIN2).	Brassinosteroids	164-179	Protein kinase superfamily protein	Arabidopsis thaliana	285-289
17873094-8	2007	We propose that the spatial redistribution of BZR1 is critical for proper BR signaling in plant growth and development.	Brassinosteroids	74-76	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	46-50
17583510-4	2007	Here we demonstrate that the Arabidopsis thaliana Brassinosteroid Insensitive 1 (BRI1)-associated receptor Kinase 1 (BAK1), which operates as a coreceptor of BRI1 in brassinolide (BL)-dependent plant development, also regulates the containment of microbial infection-induced cell death.	Brassinosteroids	50-65	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	81-85
17583510-4	2007	Here we demonstrate that the Arabidopsis thaliana Brassinosteroid Insensitive 1 (BRI1)-associated receptor Kinase 1 (BAK1), which operates as a coreceptor of BRI1 in brassinolide (BL)-dependent plant development, also regulates the containment of microbial infection-induced cell death.	Brassinosteroids	50-65	BRI1-associated receptor kinase	Arabidopsis thaliana	117-121
17583510-4	2007	Here we demonstrate that the Arabidopsis thaliana Brassinosteroid Insensitive 1 (BRI1)-associated receptor Kinase 1 (BAK1), which operates as a coreceptor of BRI1 in brassinolide (BL)-dependent plant development, also regulates the containment of microbial infection-induced cell death.	Brassinosteroids	50-65	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	158-162
17521414-0	2007	BEN1, a gene encoding a dihydroflavonol 4-reductase (DFR)-like protein, regulates the levels of brassinosteroids in Arabidopsis thaliana.	Brassinosteroids	96-112	NAD(P)-binding Rossmann-fold superfamily protein	Arabidopsis thaliana	0-4
17521414-0	2007	BEN1, a gene encoding a dihydroflavonol 4-reductase (DFR)-like protein, regulates the levels of brassinosteroids in Arabidopsis thaliana.	Brassinosteroids	96-112	dihydroflavonol 4-reductase	Arabidopsis thaliana	24-51
17521414-0	2007	BEN1, a gene encoding a dihydroflavonol 4-reductase (DFR)-like protein, regulates the levels of brassinosteroids in Arabidopsis thaliana.	Brassinosteroids	96-112	dihydroflavonol 4-reductase	Arabidopsis thaliana	53-56
17521414-6	2007	Analyses of brassinosteroid profiles demonstrated that BEN1 is indeed responsible for regulating the levels of several brassinosteroids, including typhasterol, castasterone and brassinolide.	Brassinosteroids	119-135	NAD(P)-binding Rossmann-fold superfamily protein	Arabidopsis thaliana	55-59
17521414-7	2007	In vivo feeding and in vitro biochemical assays suggest that BEN1 is probably involved in a new mechanism to regulate brassinosteroid levels.	Brassinosteroids	118-133	NAD(P)-binding Rossmann-fold superfamily protein	Arabidopsis thaliana	61-65
17588517-5	2007	We demonstrated that bri1-9 is retained in the ER through interactions with several ER chaperones and that ebs1 mutations significantly reduce the stringency of the retention-based ER quality control, allowing export of the structurally imperfect yet biochemically competent bri1-9 to the cell surface for BR perception.	Brassinosteroids	306-308	EMS-MUTAGENIZED BRI1 SUPPRESSOR 1	Arabidopsis thaliana	107-111
17027118-2	2007	Brassinosteroid insensitive1 (BRI1)-assocaiated receptor kinase (BAK1) is one of the key components in the BR signal transduction pathway due to its direct association with the BR receptor, BRI1.	Brassinosteroids	0-15	BRI1-associated receptor kinase	Arabidopsis thaliana	65-69
17027118-4	2007	This article provides the first piece of evidence that AtBAK1 can greatly affect growth and development of rice plants when ectopically expressed, suggesting that rice may share similar BR perception mechanism via BRI1/BAK1 complex.	Brassinosteroids	186-188	BRI1-associated receptor kinase	Arabidopsis thaliana	55-61
17027118-4	2007	This article provides the first piece of evidence that AtBAK1 can greatly affect growth and development of rice plants when ectopically expressed, suggesting that rice may share similar BR perception mechanism via BRI1/BAK1 complex.	Brassinosteroids	186-188	BRI1-associated receptor kinase	Arabidopsis thaliana	57-61
17039368-7	2007	Among the three recombinant enzymes, only AtST4a was catalytically active with brassinosteroids.	Brassinosteroids	79-95	sulfotransferase 4A	Arabidopsis thaliana	42-48
17039368-4	2007	AtST4a was specific for biologically active end products of the brassinosteroid pathway.	Brassinosteroids	64-79	sulfotransferase 4A	Arabidopsis thaliana	0-6
17052323-0	2006	The rice SPINDLY gene functions as a negative regulator of gibberellin signaling by controlling the suppressive function of the DELLA protein, SLR1, and modulating brassinosteroid synthesis.	Brassinosteroids	164-179	Tetratricopeptide repeat (TPR)-like superfamily protein	Arabidopsis thaliana	9-16
17138693-0	2006	C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis.	Brassinosteroids	82-97	Cytochrome P450 superfamily protein	Arabidopsis thaliana	34-41
17138693-0	2006	C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis.	Brassinosteroids	82-97	cytochrome P450, family 90, subfamily D, polypeptide 1	Arabidopsis thaliana	46-53
17138693-2	2006	We report the functional characterization of two BR-biosynthetic P450s from Arabidopsis thaliana: CYP90C1/ROTUNDIFOLIA3 and CYP90D1.	Brassinosteroids	49-51	Cytochrome P450 superfamily protein	Arabidopsis thaliana	98-105
17138693-2	2006	We report the functional characterization of two BR-biosynthetic P450s from Arabidopsis thaliana: CYP90C1/ROTUNDIFOLIA3 and CYP90D1.	Brassinosteroids	49-51	cytochrome P450, family 90, subfamily D, polypeptide 1	Arabidopsis thaliana	124-131
17006513-0	2006	BRX mediates feedback between brassinosteroid levels and auxin signalling in root growth.	Brassinosteroids	30-45	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	0-3
16905670-9	2006	We further illustrate that RPN9 functions at least in part through regulation of auxin transport and brassinosteroid signaling, two processes that are crucial for vascular formation.	Brassinosteroids	101-116	proteasome 26S subunit, non-ATPase 13	Homo sapiens	27-31
17006513-7	2006	Moreover, embryonic or post-embryonic brassinosteroid application fully or partially, respectively, rescues the brx phenotype.	Brassinosteroids	38-53	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	112-115
17006513-8	2006	Further, auxin-responsive gene expression is globally impaired in brx, demonstrating that brassinosteroid levels are rate-limiting for auxin-responsive transcription.	Brassinosteroids	90-105	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	66-69
17006513-9	2006	BRX expression is strongly induced by auxin and mildly repressed by brassinolide, which means that BRX acts at the nexus of a feedback loop that maintains threshold brassinosteroid levels to permit optimal auxin action.	Brassinosteroids	165-180	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	0-3
17006513-9	2006	BRX expression is strongly induced by auxin and mildly repressed by brassinolide, which means that BRX acts at the nexus of a feedback loop that maintains threshold brassinosteroid levels to permit optimal auxin action.	Brassinosteroids	165-180	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	99-102
17003466-3	2006	BR binding to the extracellular domain of the receptor BRI1 induces kinase activation and hetero-oligomerization with the second transmembrane kinase BAK1.	Brassinosteroids	0-2	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	55-59
17003466-3	2006	BR binding to the extracellular domain of the receptor BRI1 induces kinase activation and hetero-oligomerization with the second transmembrane kinase BAK1.	Brassinosteroids	0-2	BRI1-associated receptor kinase	Arabidopsis thaliana	150-154
17003466-5	2006	In the presence of BR, the kinase BIN2, which is the Arabidopsis homolog of GSK3 (glycogen synthase kinase 3), is inhibited by an unknown mechanism, leading to dephosphorylation of BES1 and BZR1 inside the nucleus.	Brassinosteroids	19-21	Protein kinase superfamily protein	Arabidopsis thaliana	34-38
17003466-5	2006	In the presence of BR, the kinase BIN2, which is the Arabidopsis homolog of GSK3 (glycogen synthase kinase 3), is inhibited by an unknown mechanism, leading to dephosphorylation of BES1 and BZR1 inside the nucleus.	Brassinosteroids	19-21	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	181-185
17003466-5	2006	In the presence of BR, the kinase BIN2, which is the Arabidopsis homolog of GSK3 (glycogen synthase kinase 3), is inhibited by an unknown mechanism, leading to dephosphorylation of BES1 and BZR1 inside the nucleus.	Brassinosteroids	19-21	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	190-194
16960392-0	2006	CYP724B2 and CYP90B3 function in the early C-22 hydroxylation steps of brassinosteroid biosynthetic pathway in tomato.	Brassinosteroids	71-86	cytochrome P450 724B1-like	Solanum lycopersicum	0-8
16960392-0	2006	CYP724B2 and CYP90B3 function in the early C-22 hydroxylation steps of brassinosteroid biosynthetic pathway in tomato.	Brassinosteroids	71-86	cytochrome P450 90B3	Solanum lycopersicum	13-20
16960392-10	2006	These findings strongly suggest that CYP724B2 and CYP90B3 function in the early C-22 hydroxylation steps of brassinosteroid biosynthetic pathway in tomato.	Brassinosteroids	108-123	cytochrome P450 724B1-like	Solanum lycopersicum	37-45
16960392-10	2006	These findings strongly suggest that CYP724B2 and CYP90B3 function in the early C-22 hydroxylation steps of brassinosteroid biosynthetic pathway in tomato.	Brassinosteroids	108-123	cytochrome P450 90B3	Solanum lycopersicum	50-57
17080598-3	2006	Several key elements of BR response have been identified using both genetic and biochemical approaches, and molecular models that parallel Wingless (Wnt), transforming growth factor beta (TGF beta) and receptor tyrosine kinase (RTK) signalling in animals have been proposed.	Brassinosteroids	24-26	transforming growth factor beta 1	Homo sapiens	155-186
16872648-0	2006	Tomato cytochrome P450 CYP734A7 functions in brassinosteroid catabolism.	Brassinosteroids	45-60	castasterone 26-hydroxylase	Solanum lycopersicum	23-31
16872648-4	2006	Transgenic tobacco plants that constitutively overexpressed CYP734A7 showed an extreme dwarf phenotype similar to BR deficiency.	Brassinosteroids	114-116	castasterone 26-hydroxylase	Solanum lycopersicum	60-68
16872648-10	2006	These results indicated that CYP734A7 is a C-26 hydroxylase of BRs and is likely involved in BR catabolism in tomato.	Brassinosteroids	63-65	castasterone 26-hydroxylase	Solanum lycopersicum	29-37
16632588-0	2006	Inhibition of brassinosteroid biosynthesis by either a dwarf4 mutation or a brassinosteroid biosynthesis inhibitor rescues defects in tropic responses of hypocotyls in the arabidopsis mutant nonphototropic hypocotyl 4.	Brassinosteroids	14-29	Cytochrome P450 superfamily protein	Arabidopsis thaliana	55-61
16632588-0	2006	Inhibition of brassinosteroid biosynthesis by either a dwarf4 mutation or a brassinosteroid biosynthesis inhibitor rescues defects in tropic responses of hypocotyls in the arabidopsis mutant nonphototropic hypocotyl 4.	Brassinosteroids	14-29	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	191-217
16632588-0	2006	Inhibition of brassinosteroid biosynthesis by either a dwarf4 mutation or a brassinosteroid biosynthesis inhibitor rescues defects in tropic responses of hypocotyls in the arabidopsis mutant nonphototropic hypocotyl 4.	Brassinosteroids	76-91	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	191-217
16632588-8	2006	Treatment with brassinazole, an inhibitor of BR biosynthesis, also partially rescued the tropic defects in nph4-103.	Brassinosteroids	45-47	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	107-111
16632588-14	2006	These results strongly suggest that BR deficiency suppresses nph4-103 defects in tropic responses of hypocotyls and differential growth of leaves and that BR negatively regulates tropic responses.	Brassinosteroids	36-38	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	61-65
16672972-2	2006	BRs bind to the plasma membrane receptor kinase BRI1, and act through a signalling pathway that involves a glycogen synthase kinase-3-like kinase (BIN2) and a serine/threonine phosphatase (BSU1).	Brassinosteroids	0-3	bridging integrator 2	Homo sapiens	147-151
16672972-3	2006	Previous models proposed that BIN2 negatively regulates BR signalling by controlling the stability and subcellular localization of the related transcription factors BES1 and BZR1 by phosphorylation, in a manner reminiscent of the canonical Wnt signalling pathway of metazoans.	Brassinosteroids	56-58	bridging integrator 2	Homo sapiens	30-34
16699538-3	2006	Recent studies have demonstrated that BR binding to the extracellular domain of BRI1 induces kinase activation and dimerization with another receptor kinase, BAK1.	Brassinosteroids	38-40	BCL2 antagonist/killer 1	Homo sapiens	158-162
16531479-0	2006	Diurnal regulation of the brassinosteroid-biosynthetic CPD gene in Arabidopsis.	Brassinosteroids	26-41	Cytochrome P450 superfamily protein	Arabidopsis thaliana	55-58
16531479-7	2006	Diurnal changes in the expression of CPD and CYP85A2 are accompanied by changes of the endogenous BR content during the day, leading to brassinolide accumulation at the middle of the light phase.	Brassinosteroids	98-100	Cytochrome P450 superfamily protein	Arabidopsis thaliana	37-40
16531479-7	2006	Diurnal changes in the expression of CPD and CYP85A2 are accompanied by changes of the endogenous BR content during the day, leading to brassinolide accumulation at the middle of the light phase.	Brassinosteroids	98-100	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	45-52
16792696-9	2006	Affymetrix GeneChip array analysis showed that the expressions of many of the genes involved in the biosynthesis of plant hormones (e.g. ethylene, brassinosteroid, gibberellic acid) were significantly changed in the 35S::XERICO plants.	Brassinosteroids	147-162	RING/U-box superfamily protein	Arabidopsis thaliana	221-227
16824178-6	2006	ARL is upregulated by brassinosteroid (BR) and this induction is impaired in the BR-insensitive mutant bri1, but not in the BR-deficient mutant det2.	Brassinosteroids	22-37	ARGOS-like protein	Arabidopsis thaliana	0-3
16824178-6	2006	ARL is upregulated by brassinosteroid (BR) and this induction is impaired in the BR-insensitive mutant bri1, but not in the BR-deficient mutant det2.	Brassinosteroids	22-37	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	103-107
17080598-3	2006	Several key elements of BR response have been identified using both genetic and biochemical approaches, and molecular models that parallel Wingless (Wnt), transforming growth factor beta (TGF beta) and receptor tyrosine kinase (RTK) signalling in animals have been proposed.	Brassinosteroids	24-26	transforming growth factor beta 1	Homo sapiens	188-196
17080598-3	2006	Several key elements of BR response have been identified using both genetic and biochemical approaches, and molecular models that parallel Wingless (Wnt), transforming growth factor beta (TGF beta) and receptor tyrosine kinase (RTK) signalling in animals have been proposed.	Brassinosteroids	24-26	ret proto-oncogene	Homo sapiens	202-226
17080598-3	2006	Several key elements of BR response have been identified using both genetic and biochemical approaches, and molecular models that parallel Wingless (Wnt), transforming growth factor beta (TGF beta) and receptor tyrosine kinase (RTK) signalling in animals have been proposed.	Brassinosteroids	24-26	ret proto-oncogene	Homo sapiens	228-231
16407451-8	2006	DWF4:GUS activity was increased by treatment with brassinazole, a BR biosynthetic inhibitor, and decreased by exogenous application of bioactive BRs.	Brassinosteroids	66-68	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-4
16407451-0	2006	The regulation of DWARF4 expression is likely a critical mechanism in maintaining the homeostasis of bioactive brassinosteroids in Arabidopsis.	Brassinosteroids	111-127	Cytochrome P450 superfamily protein	Arabidopsis thaliana	18-24
16407451-2	2006	Arabidopsis (Arabidopsis thaliana) DWARF4 (DWF4) catalyzes a flux-determining step in the BR biosynthetic pathways.	Brassinosteroids	90-92	Cytochrome P450 superfamily protein	Arabidopsis thaliana	35-41
16407451-2	2006	Arabidopsis (Arabidopsis thaliana) DWARF4 (DWF4) catalyzes a flux-determining step in the BR biosynthetic pathways.	Brassinosteroids	90-92	Cytochrome P450 superfamily protein	Arabidopsis thaliana	43-47
16407451-3	2006	Thus, it is hypothesized that the tissues of DWF4 expression may represent the sites of BR biosynthesis in Arabidopsis.	Brassinosteroids	88-90	Cytochrome P450 superfamily protein	Arabidopsis thaliana	45-49
16407451-11	2006	Thus, it is likely that the DWF4 promoter serves as a focal point in maintaining homeostasis of endogenous bioactive BR pools in specific tissues of Arabidopsis.	Brassinosteroids	117-119	Cytochrome P450 superfamily protein	Arabidopsis thaliana	28-32
16412086-7	2006	Furthermore, 35S::MIF1 seedlings were demonstrated to be non-responsive to gibberellin (GA) for cell elongation, hypersensitive to the GA synthesis inhibitor paclobutrazol (PAC) and abscisic acid (ABA), and hyposensitive to auxin, brassinosteroid and cytokinin, but normally responsive to ethylene.	Brassinosteroids	231-246	mini zinc finger 1	Arabidopsis thaliana	18-22
16829549-6	2006	rack1a mutants displayed reduced sensitivity to gibberellin and brassinosteroid in seed germination, hypersensitivity to abscisic acid in seed germination and early seedling development, and hyposensitivity to auxin in adventitious and lateral root formation.	Brassinosteroids	64-79	Transducin/WD40 repeat-like superfamily protein	Arabidopsis thaliana	0-6
16183327-2	2005	Recent studies, particularly of the BRASSINOSTEROID INSENSITIVE1 RLK, have begun to shed light on the mechanistic details of RLK activation, including the possible role of ligand binding.	Brassinosteroids	36-51	TXK tyrosine kinase	Homo sapiens	65-68
16183327-2	2005	Recent studies, particularly of the BRASSINOSTEROID INSENSITIVE1 RLK, have begun to shed light on the mechanistic details of RLK activation, including the possible role of ligand binding.	Brassinosteroids	36-51	TXK tyrosine kinase	Homo sapiens	125-128
15994910-0	2005	The Rice brassinosteroid-deficient dwarf2 mutant, defective in the rice homolog of Arabidopsis DIMINUTO/DWARF1, is rescued by the endogenously accumulated alternative bioactive brassinosteroid, dolichosterone.	Brassinosteroids	9-24	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	104-110
16123046-2	2005	Its biological role in the brassinosteroid signaling pathway was first established by its capability to specifically suppress a weak brassinosteroid insensitive 1 (bri1) allele, bri1-5, when overexpressed.	Brassinosteroids	27-42	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	164-168
16123046-2	2005	Its biological role in the brassinosteroid signaling pathway was first established by its capability to specifically suppress a weak brassinosteroid insensitive 1 (bri1) allele, bri1-5, when overexpressed.	Brassinosteroids	27-42	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	178-184
16214889-0	2005	The UGT73C5 of Arabidopsis thaliana glucosylates brassinosteroids.	Brassinosteroids	49-65	don-glucosyltransferase 1	Arabidopsis thaliana	4-11
16214889-5	2005	Transgenic plants overexpressing UGT73C5 displayed BR-deficient phenotypes and contained reduced amounts of BRs.	Brassinosteroids	51-53	don-glucosyltransferase 1	Arabidopsis thaliana	33-40
16193053-4	2005	Arabidopsis DWARF1 (DWF1) is responsible for an early step in brassinosteroid biosynthesis that converts 24-methylenecholesterol to campesterol.	Brassinosteroids	62-77	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	12-18
16193053-4	2005	Arabidopsis DWARF1 (DWF1) is responsible for an early step in brassinosteroid biosynthesis that converts 24-methylenecholesterol to campesterol.	Brassinosteroids	62-77	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	20-24
15973517-2	2005	To begin to understand the role of BR-mediated responses in the development of cotton fibers we have characterized the BIN 2 genes of cotton.	Brassinosteroids	35-37	Protein kinase superfamily protein	Arabidopsis thaliana	119-124
16024588-0	2005	Arabidopsis CYP85A2, a cytochrome P450, mediates the Baeyer-Villiger oxidation of castasterone to brassinolide in brassinosteroid biosynthesis.	Brassinosteroids	114-129	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	12-19
16024588-2	2005	Heterologously expressed Arabidopsis thaliana CYP85A2 in yeast mediated the conversion of CS to BL as well as the C-6 oxidation of brassinosteroids (BRs).	Brassinosteroids	131-147	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	46-53
16024588-5	2005	Biochemical, physiological, and molecular genetic analyses of Arabidopsis CYP85A2 loss-of-function and overexpression lines demonstrated that CS has to be a bioactive BR that controls the overall growth and development of Arabidopsis plants.	Brassinosteroids	167-169	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	74-81
16126860-0	2005	A brassinosteroid-hypersensitive mutant of BAK1 indicates that a convergence of photomorphogenic and hormonal signaling modulates phototropism.	Brassinosteroids	2-17	BRI1-associated receptor kinase	Arabidopsis thaliana	43-47
15994910-8	2005	Based on these observations, we discuss an alternative BR biosynthetic pathway that produces DS when Dim/dwf1 is defective.	Brassinosteroids	55-57	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	101-104
15994910-8	2005	Based on these observations, we discuss an alternative BR biosynthetic pathway that produces DS when Dim/dwf1 is defective.	Brassinosteroids	55-57	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	105-109
15935775-1	2005	The leucine-rich-repeat receptor serine/threonine kinase, BRI1, is a cell-surface receptor for brassinosteroids (BRs), the steroid hormones of plants, yet its activation mechanism is unknown.	Brassinosteroids	95-111	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	58-62
15998311-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE 1 (BRI1) receptor serine/threonine kinase for hormone perception and signal transduction.	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	134-138
15998311-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE 1 (BRI1) receptor serine/threonine kinase for hormone perception and signal transduction.	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	134-138
15998311-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE 1 (BRI1) receptor serine/threonine kinase for hormone perception and signal transduction.	Brassinosteroids	103-118	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	134-138
15998311-8	2005	These findings support a role for TRIP-1 in the molecular mechanisms of BR-regulated plant growth and development, possibly as a cytoplasmic substrate of the BRI1 receptor kinase.	Brassinosteroids	72-74	TGF-beta receptor interacting protein 1	Arabidopsis thaliana	34-40
15998311-8	2005	These findings support a role for TRIP-1 in the molecular mechanisms of BR-regulated plant growth and development, possibly as a cytoplasmic substrate of the BRI1 receptor kinase.	Brassinosteroids	72-74	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	158-162
15935775-1	2005	The leucine-rich-repeat receptor serine/threonine kinase, BRI1, is a cell-surface receptor for brassinosteroids (BRs), the steroid hormones of plants, yet its activation mechanism is unknown.	Brassinosteroids	113-116	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	58-62
15935775-3	2005	Removal of BRI1"s C terminus leads to a hypersensitive receptor, indicated by suppression of dwarfism of BR-deficient and BR-perception mutants and by enhanced BR signaling as a result of elevated phosphorylation of BRI1.	Brassinosteroids	11-13	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	216-220
15894717-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) for hormone perception and signal transduction.	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	103-131
15894717-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) for hormone perception and signal transduction.	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	133-137
15908602-3	2005	Five BR-specific biosynthesis genes (DET2, DWF4, CPD, BR6ox1, and ROT3) and two sterol biosynthesis genes (FK and DWF5) were up-regulated in BR-depleted wild-type plants grown under brassinazole, a BR biosynthesis inhibitor.	Brassinosteroids	5-7	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	37-41
15908602-3	2005	Five BR-specific biosynthesis genes (DET2, DWF4, CPD, BR6ox1, and ROT3) and two sterol biosynthesis genes (FK and DWF5) were up-regulated in BR-depleted wild-type plants grown under brassinazole, a BR biosynthesis inhibitor.	Brassinosteroids	5-7	Cytochrome P450 superfamily protein	Arabidopsis thaliana	43-47
15894717-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) for hormone perception and signal transduction.	Brassinosteroids	0-16	BRI1-associated receptor kinase	Arabidopsis thaliana	143-175
15894717-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) for hormone perception and signal transduction.	Brassinosteroids	0-16	BRI1-associated receptor kinase	Arabidopsis thaliana	177-181
15908602-3	2005	Five BR-specific biosynthesis genes (DET2, DWF4, CPD, BR6ox1, and ROT3) and two sterol biosynthesis genes (FK and DWF5) were up-regulated in BR-depleted wild-type plants grown under brassinazole, a BR biosynthesis inhibitor.	Brassinosteroids	5-7	brassinosteroid-6-oxidase 1	Arabidopsis thaliana	54-60
15894717-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) for hormone perception and signal transduction.	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	103-131
15908602-3	2005	Five BR-specific biosynthesis genes (DET2, DWF4, CPD, BR6ox1, and ROT3) and two sterol biosynthesis genes (FK and DWF5) were up-regulated in BR-depleted wild-type plants grown under brassinazole, a BR biosynthesis inhibitor.	Brassinosteroids	5-7	Cytochrome P450 superfamily protein	Arabidopsis thaliana	66-70
15894717-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) for hormone perception and signal transduction.	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	133-137
15908602-3	2005	Five BR-specific biosynthesis genes (DET2, DWF4, CPD, BR6ox1, and ROT3) and two sterol biosynthesis genes (FK and DWF5) were up-regulated in BR-depleted wild-type plants grown under brassinazole, a BR biosynthesis inhibitor.	Brassinosteroids	5-7	Ergosterol biosynthesis ERG4/ERG24 family	Arabidopsis thaliana	114-118
15908602-3	2005	Five BR-specific biosynthesis genes (DET2, DWF4, CPD, BR6ox1, and ROT3) and two sterol biosynthesis genes (FK and DWF5) were up-regulated in BR-depleted wild-type plants grown under brassinazole, a BR biosynthesis inhibitor.	Brassinosteroids	54-56	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	37-41
15908602-5	2005	However, their response to fluctuation of BR levels was highly reduced (DWF4) or nullified (the other eight genes) in a bri1 mutant.	Brassinosteroids	42-44	Cytochrome P450 superfamily protein	Arabidopsis thaliana	72-76
15908602-5	2005	However, their response to fluctuation of BR levels was highly reduced (DWF4) or nullified (the other eight genes) in a bri1 mutant.	Brassinosteroids	42-44	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	120-124
15894717-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) for hormone perception and signal transduction.	Brassinosteroids	18-21	BRI1-associated receptor kinase	Arabidopsis thaliana	143-175
15894717-1	2005	Brassinosteroids (BRs) regulate multiple aspects of plant growth and development and require an active BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED RECEPTOR KINASE1 (BAK1) for hormone perception and signal transduction.	Brassinosteroids	18-21	BRI1-associated receptor kinase	Arabidopsis thaliana	177-181
15894717-3	2005	To determine if early events in BR signaling share this mechanism, we used coimmunoprecipitation of epitope-tagged proteins to show that in vivo association of BRI1 and BAK1 was affected by endogenous and exogenous BR levels and that phosphorylation of both BRI1 and BAK1 on Thr residues was BR dependent.	Brassinosteroids	32-34	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	160-164
15894717-3	2005	To determine if early events in BR signaling share this mechanism, we used coimmunoprecipitation of epitope-tagged proteins to show that in vivo association of BRI1 and BAK1 was affected by endogenous and exogenous BR levels and that phosphorylation of both BRI1 and BAK1 on Thr residues was BR dependent.	Brassinosteroids	32-34	BRI1-associated receptor kinase	Arabidopsis thaliana	169-173
15773850-8	2005	We propose that CYP72C1 controls BR homeostasis by modulating the concentration of BRs.	Brassinosteroids	33-35	cytochrome p450 72c1	Arabidopsis thaliana	16-23
16011030-1	2005	Gene CPD (constitutive photomorphogenesis and dwarf) encodes a cytochrome P450 steroid side-chain hydroxylase (CYP90) involved in biosynthesis of brassinosteroids (BRs) in Arabidopsis thanalia.	Brassinosteroids	146-162	Cytochrome P450 superfamily protein	Arabidopsis thaliana	111-116
16011030-5	2005	Also it shared high homologies with the Arabidopsis CYP90 in all known functional domains,including steroid-binding region closely related to BR biosynthesis, indicating a high conservatism of the putative CDP gene between annual herb and perennial woody plant species.	Brassinosteroids	142-144	Cytochrome P450 superfamily protein	Arabidopsis thaliana	52-57
15773851-0	2005	BAS1 and SOB7 act redundantly to modulate Arabidopsis photomorphogenesis via unique brassinosteroid inactivation mechanisms.	Brassinosteroids	84-99	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-4
15773851-0	2005	BAS1 and SOB7 act redundantly to modulate Arabidopsis photomorphogenesis via unique brassinosteroid inactivation mechanisms.	Brassinosteroids	84-99	cytochrome p450 72c1	Arabidopsis thaliana	9-13
16212492-4	2005	BR perception initiates a signaling cascade, acting through a GSK3 kinase, BIN2, and the BSU1 phosphatase, which in turn modulates the phosphorylation state and stability of the nuclear transcription factors BES1 and BZR1.	Brassinosteroids	0-2	bridging integrator 2	Homo sapiens	75-79
15689343-0	2005	Activation of the cytochrome P450 gene, CYP72C1, reduces the levels of active brassinosteroids in vivo.	Brassinosteroids	78-94	cytochrome p450 72c1	Arabidopsis thaliana	40-47
15689343-8	2005	Consistent with the morphological and physiological phenotype, the levels of active brassinosteroids were reduced in the chi2 mutant.	Brassinosteroids	84-100	cytochrome p450 72c1	Arabidopsis thaliana	121-125
15689343-9	2005	Hence, CYP72C1, together with BAS1/CYP72B1, is speculated to regulate active brassinosteroid levels in plants.	Brassinosteroids	77-92	cytochrome p450 72c1	Arabidopsis thaliana	7-14
15689343-9	2005	Hence, CYP72C1, together with BAS1/CYP72B1, is speculated to regulate active brassinosteroid levels in plants.	Brassinosteroids	77-92	Cytochrome P450 superfamily protein	Arabidopsis thaliana	30-34
15689343-9	2005	Hence, CYP72C1, together with BAS1/CYP72B1, is speculated to regulate active brassinosteroid levels in plants.	Brassinosteroids	77-92	Cytochrome P450 superfamily protein	Arabidopsis thaliana	35-42
15721951-0	2005	Synthesis and bioactivity of C-29 brassinosteroid analogues with different functional groups at C-6.	Brassinosteroids	34-49	complement C6	Homo sapiens	96-99
15703058-0	2005	CYP90C1 and CYP90D1 are involved in different steps in the brassinosteroid biosynthesis pathway in Arabidopsis thaliana.	Brassinosteroids	59-74	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-7
15703058-0	2005	CYP90C1 and CYP90D1 are involved in different steps in the brassinosteroid biosynthesis pathway in Arabidopsis thaliana.	Brassinosteroids	59-74	cytochrome P450, family 90, subfamily D, polypeptide 1	Arabidopsis thaliana	12-19
15486337-1	2004	Plant steroid hormones, brassinosteroids (BRs), are perceived by the plasma membrane-localized leucine-rich-repeat-receptor kinase BRI1.	Brassinosteroids	24-40	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	131-135
16492480-10	2005	Following the isolation of det2 and cpd, a great number of BR-deficient mutants were identified.	Brassinosteroids	59-61	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	27-31
15773850-0	2005	shk1-D, a dwarf Arabidopsis mutant caused by activation of the CYP72C1 gene, has altered brassinosteroid levels.	Brassinosteroids	89-104	cytochrome p450 72c1	Arabidopsis thaliana	0-4
15773850-0	2005	shk1-D, a dwarf Arabidopsis mutant caused by activation of the CYP72C1 gene, has altered brassinosteroid levels.	Brassinosteroids	89-104	cytochrome p450 72c1	Arabidopsis thaliana	63-70
15486337-1	2004	Plant steroid hormones, brassinosteroids (BRs), are perceived by the plasma membrane-localized leucine-rich-repeat-receptor kinase BRI1.	Brassinosteroids	42-45	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	131-135
15159624-2	2004	Plant responses to brassinosteroids (BR) are mediated through a plasma membrane-bound leucine-rich repeat (LRR) receptor-like protein kinase known as BRI1.	Brassinosteroids	19-35	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	150-154
15319482-2	2004	It is believed that BRI1 becomes activated through heterodimerization with BAK1, a similar LRR receptor kinase, in response to BR signal.	Brassinosteroids	20-22	BRI1-associated receptor kinase	Arabidopsis thaliana	75-79
15181210-0	2004	GCR1 can act independently of heterotrimeric G-protein in response to brassinosteroids and gibberellins in Arabidopsis seed germination.	Brassinosteroids	70-86	G-protein-coupled receptor 1	Arabidopsis thaliana	0-4
15181210-8	2004	However, the reduced sensitivities toward GA and BR in the single gcr1, gpa1, and agb1 (heterotrimeric G-protein beta-subunit) mutants are additive or synergistic in the double and triple mutants.	Brassinosteroids	49-51	G-protein-coupled receptor 1	Arabidopsis thaliana	66-70
15181210-8	2004	However, the reduced sensitivities toward GA and BR in the single gcr1, gpa1, and agb1 (heterotrimeric G-protein beta-subunit) mutants are additive or synergistic in the double and triple mutants.	Brassinosteroids	49-51	G protein alpha subunit 1	Arabidopsis thaliana	72-76
15181210-8	2004	However, the reduced sensitivities toward GA and BR in the single gcr1, gpa1, and agb1 (heterotrimeric G-protein beta-subunit) mutants are additive or synergistic in the double and triple mutants.	Brassinosteroids	49-51	GTP binding protein beta 1	Arabidopsis thaliana	82-86
14730066-0	2004	The ULTRACURVATA2 gene of Arabidopsis encodes an FK506-binding protein involved in auxin and brassinosteroid signaling.	Brassinosteroids	93-108	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	4-17
15234272-3	2004	In the present study, a synthetic peptide based on the known regulatory phosphorylation site (KKNNLRLS460FSKRMY) in LeACS2 was found to be readily phosphorylated in vitro by several calcium-dependent protein kinases (CDPKs), but not a plant SNF1-related protein kinase or the kinase domain of the receptor-like kinase, BRI1, involved in brassinosteroid signaling.	Brassinosteroids	337-352	1-aminocyclopropane-1-carboxylate synthase 2	Solanum lycopersicum	116-122
15234272-3	2004	In the present study, a synthetic peptide based on the known regulatory phosphorylation site (KKNNLRLS460FSKRMY) in LeACS2 was found to be readily phosphorylated in vitro by several calcium-dependent protein kinases (CDPKs), but not a plant SNF1-related protein kinase or the kinase domain of the receptor-like kinase, BRI1, involved in brassinosteroid signaling.	Brassinosteroids	337-352	SNF1-related protein kinase	Solanum lycopersicum	241-268
15234272-3	2004	In the present study, a synthetic peptide based on the known regulatory phosphorylation site (KKNNLRLS460FSKRMY) in LeACS2 was found to be readily phosphorylated in vitro by several calcium-dependent protein kinases (CDPKs), but not a plant SNF1-related protein kinase or the kinase domain of the receptor-like kinase, BRI1, involved in brassinosteroid signaling.	Brassinosteroids	337-352	brassinosteroid LRR receptor kinase	Solanum lycopersicum	319-323
15040885-0	2004	Arabidopsis RAV1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development.	Brassinosteroids	38-53	related to ABI3/VP1 1	Arabidopsis thaliana	12-16
15102375-3	2004	In plants, brassinosteroids (BRs) are perceived by the cell surface receptor kinase BRI1, which is distinct from the animal steroid receptors.	Brassinosteroids	11-27	brassinosteroid LRR receptor kinase	Solanum lycopersicum	84-88
15102375-3	2004	In plants, brassinosteroids (BRs) are perceived by the cell surface receptor kinase BRI1, which is distinct from the animal steroid receptors.	Brassinosteroids	29-32	brassinosteroid LRR receptor kinase	Solanum lycopersicum	84-88
14730066-2	2004	We have previously determined that the UCU1 gene encodes a SHAGGY/GSK3-like kinase that participates in the signaling pathways of auxins and brassinosteroids.	Brassinosteroids	141-157	Protein kinase superfamily protein	Arabidopsis thaliana	39-43
14730066-5	2004	Physiological and double mutant analyses suggest that UCU2 is required for growth and development and participates in auxin and brassinosteroid signaling.	Brassinosteroids	128-143	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	54-58
15159624-2	2004	Plant responses to brassinosteroids (BR) are mediated through a plasma membrane-bound leucine-rich repeat (LRR) receptor-like protein kinase known as BRI1.	Brassinosteroids	37-39	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	150-154
12473456-7	2003	The structural similarity of deoxycholate and brassinosteroids (BRs) ubiquitous plant steroid hormones, prompted the mass spectrometry (MS) study in order to examine whether BRs can bind to Bet v 1l.	Brassinosteroids	174-177	delta/notch like EGF repeat containing	Homo sapiens	190-193
14605216-2	2003	An Arabidopsis cytochrome p450 monooxygenase encoded by CYP72B1 has been implicated in brassinosteroid catabolism as well as photomorphogenesis.	Brassinosteroids	87-102	Cytochrome P450 superfamily protein	Arabidopsis thaliana	56-63
14605216-3	2003	We expressed CYP72B1 in yeast, coupled with brassinosteroid feeding, and established the biochemical function to be the hydroxylation of BL and castasterone, to give 26-hydroxybrassinolide and 26-hydroxycastasterone, respectively.	Brassinosteroids	44-59	Cytochrome P450 superfamily protein	Arabidopsis thaliana	13-20
14605216-4	2003	Brassinosteroid feeding experiments with wild-type Arabidopsis, a CYP72B1 null mutant, and a CYP72B1 overexpression line demonstrated that carbon 26 hydroxylation of active brassinosteroids is an endogenous function of CYP72B1.	Brassinosteroids	0-15	Cytochrome P450 superfamily protein	Arabidopsis thaliana	66-73
14605216-4	2003	Brassinosteroid feeding experiments with wild-type Arabidopsis, a CYP72B1 null mutant, and a CYP72B1 overexpression line demonstrated that carbon 26 hydroxylation of active brassinosteroids is an endogenous function of CYP72B1.	Brassinosteroids	0-15	Cytochrome P450 superfamily protein	Arabidopsis thaliana	93-100
14605216-4	2003	Brassinosteroid feeding experiments with wild-type Arabidopsis, a CYP72B1 null mutant, and a CYP72B1 overexpression line demonstrated that carbon 26 hydroxylation of active brassinosteroids is an endogenous function of CYP72B1.	Brassinosteroids	0-15	Cytochrome P450 superfamily protein	Arabidopsis thaliana	93-100
14605216-4	2003	Brassinosteroid feeding experiments with wild-type Arabidopsis, a CYP72B1 null mutant, and a CYP72B1 overexpression line demonstrated that carbon 26 hydroxylation of active brassinosteroids is an endogenous function of CYP72B1.	Brassinosteroids	173-189	Cytochrome P450 superfamily protein	Arabidopsis thaliana	66-73
14605216-4	2003	Brassinosteroid feeding experiments with wild-type Arabidopsis, a CYP72B1 null mutant, and a CYP72B1 overexpression line demonstrated that carbon 26 hydroxylation of active brassinosteroids is an endogenous function of CYP72B1.	Brassinosteroids	173-189	Cytochrome P450 superfamily protein	Arabidopsis thaliana	93-100
14605216-4	2003	Brassinosteroid feeding experiments with wild-type Arabidopsis, a CYP72B1 null mutant, and a CYP72B1 overexpression line demonstrated that carbon 26 hydroxylation of active brassinosteroids is an endogenous function of CYP72B1.	Brassinosteroids	173-189	Cytochrome P450 superfamily protein	Arabidopsis thaliana	93-100
14605216-10	2003	CYP72B1 provides an intersection between the light and brassinosteroid pathways mainly by far-red-light-dependent modulation of brassinosteroid levels.	Brassinosteroids	55-70	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-7
14605216-10	2003	CYP72B1 provides an intersection between the light and brassinosteroid pathways mainly by far-red-light-dependent modulation of brassinosteroid levels.	Brassinosteroids	128-143	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-7
14550541-2	2003	The expression pattern of the SAUR-AC1 gene, an early auxin-inducible gene in Arabidopsis, was studied in response to brassinolide (BL), in the presence of a BR-biosynthesis inhibitor, in a BR-deficient mutant, and in combination with auxin.	Brassinosteroids	158-160	SAUR-like auxin-responsive protein family	Arabidopsis thaliana	30-38
14550541-2	2003	The expression pattern of the SAUR-AC1 gene, an early auxin-inducible gene in Arabidopsis, was studied in response to brassinolide (BL), in the presence of a BR-biosynthesis inhibitor, in a BR-deficient mutant, and in combination with auxin.	Brassinosteroids	190-192	SAUR-like auxin-responsive protein family	Arabidopsis thaliana	30-38
12602867-9	2003	Proline accumulation and induction of P5CS1 transcription are simultaneously enhanced in the ABA-hypersensitive prl1 and brassinosteroid-deficient det2 mutants, whereas P5CS2 shows enhanced induction by ABA and salt only in the det2 mutant.	Brassinosteroids	121-136	delta1-pyrroline-5-carboxylate synthase 1	Arabidopsis thaliana	38-43
12602867-9	2003	Proline accumulation and induction of P5CS1 transcription are simultaneously enhanced in the ABA-hypersensitive prl1 and brassinosteroid-deficient det2 mutants, whereas P5CS2 shows enhanced induction by ABA and salt only in the det2 mutant.	Brassinosteroids	121-136	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	147-151
14605216-2	2003	An Arabidopsis cytochrome p450 monooxygenase encoded by CYP72B1 has been implicated in brassinosteroid catabolism as well as photomorphogenesis.	Brassinosteroids	87-102	Cytochrome P450 superfamily protein	Arabidopsis thaliana	15-44
14520562-3	2003	atExt1 is normally expressed in roots and inflorescences, and is induced by wounding, exogenously supplied salicylic acid, methyl jasmonate, auxins and brassinosteroids.	Brassinosteroids	152-168	extensin 4	Arabidopsis thaliana	0-6
12350224-0	2003	Triadimefon, a fungicidal triazole-type P450 inhibitor, induces brassinosteroid deficiency-like phenotypes in plants and binds to DWF4 protein in the brassinosteroid biosynthesis pathway.	Brassinosteroids	150-165	Cytochrome P450 superfamily protein	Arabidopsis thaliana	130-134
12376643-5	2002	Here, we show that induction of expression by the diverse stimuli of touch, darkness, cold, heat, and brassinosteroids (BRs) is conferred to reporter genes by the same 102-bp 5"-untranscribed TCH4 region; this result is consistent with the idea that shared regulatory elements are employed by diverse stimuli.	Brassinosteroids	102-118	Xyloglucan endotransglucosylase/hydrolase family protein	Arabidopsis thaliana	192-196
12468734-3	2002	BR content is increased in both of these mutants and is associated with increased expression of DWARF: The tomato homolog of the Arabidopsis Brassinosteroid Insensitive1 Leu-rich repeat (LRR) receptor-like kinase, named tBri1, was isolated using degenerate primers.	Brassinosteroids	0-2	brassinosteroid LRR receptor kinase	Solanum lycopersicum	220-225
12427989-0	2002	Two putative BIN2 substrates are nuclear components of brassinosteroid signaling.	Brassinosteroids	55-70	chaperonin-containing T-complex subunit CCT3	Saccharomyces cerevisiae S288C	13-17
12427989-2	2002	BIN2 is a GSK3-like kinase in Arabidopsis that functions as a negative regulator of brassinosteroid (BR) signaling.	Brassinosteroids	84-99	Protein kinase superfamily protein	Arabidopsis thaliana	0-4
12427989-2	2002	BIN2 is a GSK3-like kinase in Arabidopsis that functions as a negative regulator of brassinosteroid (BR) signaling.	Brassinosteroids	84-99	serine/threonine protein kinase RIM11	Saccharomyces cerevisiae S288C	10-14
12114546-0	2002	The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis.	Brassinosteroids	92-107	Protein kinase superfamily protein	Arabidopsis thaliana	21-25
12114546-0	2002	The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis.	Brassinosteroids	92-107	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	58-62
12114546-2	2002	BR signaling involves the cell-surface receptor BRI1, the glycogen synthase kinase-3-like kinase BIN2 as a negative regulator, and nuclear proteins BZR1 and BZR2/BES1 as positive regulators.	Brassinosteroids	0-2	Protein kinase superfamily protein	Arabidopsis thaliana	97-101
12114546-2	2002	BR signaling involves the cell-surface receptor BRI1, the glycogen synthase kinase-3-like kinase BIN2 as a negative regulator, and nuclear proteins BZR1 and BZR2/BES1 as positive regulators.	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	148-152
12114546-2	2002	BR signaling involves the cell-surface receptor BRI1, the glycogen synthase kinase-3-like kinase BIN2 as a negative regulator, and nuclear proteins BZR1 and BZR2/BES1 as positive regulators.	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	157-161
12114546-2	2002	BR signaling involves the cell-surface receptor BRI1, the glycogen synthase kinase-3-like kinase BIN2 as a negative regulator, and nuclear proteins BZR1 and BZR2/BES1 as positive regulators.	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	162-166
12114546-4	2002	Here we report that BRs induce dephosphorylation and accumulation of BZR1 protein.	Brassinosteroids	20-23	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	69-73
12114578-8	2002	Both show a mild phenotype in comparison with BR-deficient mutants such as cpd/cbb3, det2, and dwf4.	Brassinosteroids	46-48	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	85-89
12114578-8	2002	Both show a mild phenotype in comparison with BR-deficient mutants such as cpd/cbb3, det2, and dwf4.	Brassinosteroids	46-48	Cytochrome P450 superfamily protein	Arabidopsis thaliana	95-99
12427989-10	2002	We propose that BES1/BZR1 are two nuclear components of BR signaling that are negatively regulated by BIN2 through a phosphorylation-initiated process.	Brassinosteroids	56-58	chaperonin-containing T-complex subunit CCT3	Saccharomyces cerevisiae S288C	102-106
12428015-3	2002	We have isolated two new BR-insensitive mutants (dwarf12-1D and dwf12-2D) after screening Arabidopsis ethyl methanesulfonate mutant populations.	Brassinosteroids	25-27	Protein kinase superfamily protein	Arabidopsis thaliana	64-69
12445121-0	2002	Loss-of-function of a rice brassinosteroid biosynthetic enzyme, C-6 oxidase, prevents the organized arrangement and polar elongation of cells in the leaves and stem.	Brassinosteroids	27-42	6-deoxocastasterone oxidase	Solanum lycopersicum	64-75
12445121-6	2002	The accumulation profile of BR compounds in the brd1 mutants suggested that these plants may be deficient in the activity of BR C-6 oxidase.	Brassinosteroids	28-30	6-deoxocastasterone oxidase	Solanum lycopersicum	128-139
12376657-5	2002	Analysis of endogenous levels of these brassinosteroids revealed that det2 accumulates 22-OH-4-en-3-one.	Brassinosteroids	39-55	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	70-74
12215504-5	2002	SMT2 and the functionally redundant SMT3 act at a branch point in the pathway that mediates sterol and brassinosteroid levels.	Brassinosteroids	103-118	sterol methyltransferase 2	Arabidopsis thaliana	0-4
12215504-5	2002	SMT2 and the functionally redundant SMT3 act at a branch point in the pathway that mediates sterol and brassinosteroid levels.	Brassinosteroids	103-118	sterol methyltransferase 3	Arabidopsis thaliana	36-40
12215504-7	2002	As predicted from SMT2 enzymatic activity, the precursors to brassinosteroid are increased at the expense of sterols in cvp1 mutants, identifying a role for sterols in vascular cell polarization and axialization.	Brassinosteroids	61-76	sterol methyltransferase 2	Arabidopsis thaliana	18-22
12150928-0	2002	BRI1/BAK1, a receptor kinase pair mediating brassinosteroid signaling.	Brassinosteroids	44-59	BRI1-associated receptor kinase	Arabidopsis thaliana	5-9
12150929-0	2002	BAK1, an Arabidopsis LRR receptor-like protein kinase, interacts with BRI1 and modulates brassinosteroid signaling.	Brassinosteroids	89-104	BRI1-associated receptor kinase	Arabidopsis thaliana	0-4
12150929-1	2002	Brassinosteroids regulate plant growth and development through a protein complex that includes the leucine-rich repeat receptor-like protein kinase (LRR-RLK) brassinosteroid-insensitive 1 (BRI1).	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	189-193
12150929-3	2002	Overexpression of BAK1 results in elongated organ phenotypes, while a null allele of BAK1 displays a semidwarfed phenotype and has reduced sensitivity to brassinosteroids (BRs).	Brassinosteroids	154-170	BRI1-associated receptor kinase	Arabidopsis thaliana	85-89
12012249-5	2002	In wild-type Arabidopsis, the level of the BRH1 transcript was rapidly down-regulated by brassinolide, but this effect was abolished in a BR-insensitive mutant deficient in the BRI1 receptor.	Brassinosteroids	43-45	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	177-181
12068128-6	2002	We propose that this potentiation is directly mediated by brassinosteroids (BR) because the BR response and synthesis mutants, bri1-5 and det2-1, respectively, share the same GA sensitivity as gpa1 seeds.	Brassinosteroids	58-74	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	127-133
12068128-6	2002	We propose that this potentiation is directly mediated by brassinosteroids (BR) because the BR response and synthesis mutants, bri1-5 and det2-1, respectively, share the same GA sensitivity as gpa1 seeds.	Brassinosteroids	58-74	G protein alpha subunit 1	Arabidopsis thaliana	193-197
12068128-6	2002	We propose that this potentiation is directly mediated by brassinosteroids (BR) because the BR response and synthesis mutants, bri1-5 and det2-1, respectively, share the same GA sensitivity as gpa1 seeds.	Brassinosteroids	76-78	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	127-133
12068128-6	2002	We propose that this potentiation is directly mediated by brassinosteroids (BR) because the BR response and synthesis mutants, bri1-5 and det2-1, respectively, share the same GA sensitivity as gpa1 seeds.	Brassinosteroids	76-78	G protein alpha subunit 1	Arabidopsis thaliana	193-197
12012249-8	2002	Considering the potential of the RING proteins to participate in regulatory protein complexes, BR-dependent expression of BRH1 may suggest its involvement in later hormonal effects.	Brassinosteroids	95-97	brassinosteroid-responsive RING-H2	Arabidopsis thaliana	122-126
11820813-5	2002	We have positionally cloned the UCU1 gene, which encodes an AtSK protein involved in the cross-talk between auxin and brassinosteroid signaling pathways, as indicated by the responses of ucu1 mutants to plant hormones and the phenotypes of double mutants involving ucu1 alleles.	Brassinosteroids	118-133	Protein kinase superfamily protein	Arabidopsis thaliana	32-36
11820813-5	2002	We have positionally cloned the UCU1 gene, which encodes an AtSK protein involved in the cross-talk between auxin and brassinosteroid signaling pathways, as indicated by the responses of ucu1 mutants to plant hormones and the phenotypes of double mutants involving ucu1 alleles.	Brassinosteroids	118-133	Protein kinase superfamily protein	Arabidopsis thaliana	187-191
11820813-5	2002	We have positionally cloned the UCU1 gene, which encodes an AtSK protein involved in the cross-talk between auxin and brassinosteroid signaling pathways, as indicated by the responses of ucu1 mutants to plant hormones and the phenotypes of double mutants involving ucu1 alleles.	Brassinosteroids	118-133	Protein kinase superfamily protein	Arabidopsis thaliana	265-269
11867704-3	2002	When the leaves of brassinosteroid-related mutants, det2 (de-etiolated2 = cro1) and dwf1 (dwarf1 = cro2) were compared to wild-type plants, an earlier cessation of leaf expansion was observed; a detailed anatomical analysis further revealed that the mutants had fewer cells per leaf blade.	Brassinosteroids	19-34	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	52-56
11867704-3	2002	When the leaves of brassinosteroid-related mutants, det2 (de-etiolated2 = cro1) and dwf1 (dwarf1 = cro2) were compared to wild-type plants, an earlier cessation of leaf expansion was observed; a detailed anatomical analysis further revealed that the mutants had fewer cells per leaf blade.	Brassinosteroids	19-34	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	58-71
11867704-3	2002	When the leaves of brassinosteroid-related mutants, det2 (de-etiolated2 = cro1) and dwf1 (dwarf1 = cro2) were compared to wild-type plants, an earlier cessation of leaf expansion was observed; a detailed anatomical analysis further revealed that the mutants had fewer cells per leaf blade.	Brassinosteroids	19-34	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	84-88
11867704-3	2002	When the leaves of brassinosteroid-related mutants, det2 (de-etiolated2 = cro1) and dwf1 (dwarf1 = cro2) were compared to wild-type plants, an earlier cessation of leaf expansion was observed; a detailed anatomical analysis further revealed that the mutants had fewer cells per leaf blade.	Brassinosteroids	19-34	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	90-96
11867704-4	2002	Treatment of the det2 mutants with the brassinosteroid, brassinolide, reversed the mutation and restored the potential for growth to that of the wild type.	Brassinosteroids	39-54	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	17-21
11319239-0	2001	Selective interaction of triazole derivatives with DWF4, a cytochrome P450 monooxygenase of the brassinosteroid biosynthetic pathway, correlates with brassinosteroid deficiency in planta.	Brassinosteroids	96-111	Cytochrome P450 superfamily protein	Arabidopsis thaliana	51-55
11788763-7	2002	eve1 was found allelic to the brassinosteroid biosynthesis mutant dim/dwarf1.	Brassinosteroids	30-45	ubiquitin family protein	Arabidopsis thaliana	0-4
11553730-8	2001	Furthermore, bin2 mutants displayed an abscisic acid-hypersensitive phenotype that is shared by the bri1 and BR-deficient mutants.	Brassinosteroids	109-111	Protein kinase superfamily protein	Arabidopsis thaliana	13-17
11319239-0	2001	Selective interaction of triazole derivatives with DWF4, a cytochrome P450 monooxygenase of the brassinosteroid biosynthetic pathway, correlates with brassinosteroid deficiency in planta.	Brassinosteroids	96-111	Cytochrome P450 superfamily protein	Arabidopsis thaliana	59-88
11489171-0	2001	Overexpression of DWARF4 in the brassinosteroid biosynthetic pathway results in increased vegetative growth and seed yield in Arabidopsis.	Brassinosteroids	32-47	Cytochrome P450 superfamily protein	Arabidopsis thaliana	18-24
11389832-2	2001	Here, we demonstrate that a dark-induced small G protein, pea Pra2, regulates a variant cytochrome P450 that catalyzes C-2 hydroxylation in brassinosteroid biosynthesis.	Brassinosteroids	140-155	Rac family small GTPase 2	Homo sapiens	41-56
11389832-2	2001	Here, we demonstrate that a dark-induced small G protein, pea Pra2, regulates a variant cytochrome P450 that catalyzes C-2 hydroxylation in brassinosteroid biosynthesis.	Brassinosteroids	140-155	complement C2	Homo sapiens	119-122
11489171-7	2001	Analysis of endogenous BR levels in dwf4, Ws-2 and AOD4 revealed that dwf4 accumulated the precursors of the 22alpha-hydroxylation steps, whereas overexpression of DWF4 resulted in increased levels of downstream compounds relative to Ws-2, indicative of facilitated metabolic flow through the step.	Brassinosteroids	23-25	Cytochrome P450 superfamily protein	Arabidopsis thaliana	36-40
11489171-7	2001	Analysis of endogenous BR levels in dwf4, Ws-2 and AOD4 revealed that dwf4 accumulated the precursors of the 22alpha-hydroxylation steps, whereas overexpression of DWF4 resulted in increased levels of downstream compounds relative to Ws-2, indicative of facilitated metabolic flow through the step.	Brassinosteroids	23-25	Cytochrome P450 superfamily protein	Arabidopsis thaliana	70-74
11489171-7	2001	Analysis of endogenous BR levels in dwf4, Ws-2 and AOD4 revealed that dwf4 accumulated the precursors of the 22alpha-hydroxylation steps, whereas overexpression of DWF4 resulted in increased levels of downstream compounds relative to Ws-2, indicative of facilitated metabolic flow through the step.	Brassinosteroids	23-25	Cytochrome P450 superfamily protein	Arabidopsis thaliana	164-168
11123807-0	2000	Promotive effect of brassinosteroids on cell division involves a distinct CycD3-induction pathway in Arabidopsis.	Brassinosteroids	20-36	CYCLIN D3;1	Arabidopsis thaliana	74-79
11320207-1	2001	Brassinosteroid-insensitive 1 (BRI1) of Arabidopsis thaliana encodes a cell surface receptor for brassinosteroids.	Brassinosteroids	0-15	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	31-35
11320207-1	2001	Brassinosteroid-insensitive 1 (BRI1) of Arabidopsis thaliana encodes a cell surface receptor for brassinosteroids.	Brassinosteroids	97-113	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	31-35
11230564-1	2001	Brassinosteroids (BRs) are plant steroids essential for normal growth and development and can be defined as steroids that carry an oxygen moiety at C-3 and additional ones at one or more of the C-2, C-6, C-22 and C-23 carbon atoms.	Brassinosteroids	0-16	complement C3	Homo sapiens	148-151
11230564-1	2001	Brassinosteroids (BRs) are plant steroids essential for normal growth and development and can be defined as steroids that carry an oxygen moiety at C-3 and additional ones at one or more of the C-2, C-6, C-22 and C-23 carbon atoms.	Brassinosteroids	0-16	complement C2	Homo sapiens	194-197
11230564-1	2001	Brassinosteroids (BRs) are plant steroids essential for normal growth and development and can be defined as steroids that carry an oxygen moiety at C-3 and additional ones at one or more of the C-2, C-6, C-22 and C-23 carbon atoms.	Brassinosteroids	0-16	complement C6	Homo sapiens	199-202
11230564-1	2001	Brassinosteroids (BRs) are plant steroids essential for normal growth and development and can be defined as steroids that carry an oxygen moiety at C-3 and additional ones at one or more of the C-2, C-6, C-22 and C-23 carbon atoms.	Brassinosteroids	0-16	nucleolin	Homo sapiens	213-217
11230564-1	2001	Brassinosteroids (BRs) are plant steroids essential for normal growth and development and can be defined as steroids that carry an oxygen moiety at C-3 and additional ones at one or more of the C-2, C-6, C-22 and C-23 carbon atoms.	Brassinosteroids	18-21	complement C3	Homo sapiens	148-151
11230564-1	2001	Brassinosteroids (BRs) are plant steroids essential for normal growth and development and can be defined as steroids that carry an oxygen moiety at C-3 and additional ones at one or more of the C-2, C-6, C-22 and C-23 carbon atoms.	Brassinosteroids	18-21	complement C2	Homo sapiens	194-197
11230564-1	2001	Brassinosteroids (BRs) are plant steroids essential for normal growth and development and can be defined as steroids that carry an oxygen moiety at C-3 and additional ones at one or more of the C-2, C-6, C-22 and C-23 carbon atoms.	Brassinosteroids	18-21	complement C6	Homo sapiens	199-202
11230564-1	2001	Brassinosteroids (BRs) are plant steroids essential for normal growth and development and can be defined as steroids that carry an oxygen moiety at C-3 and additional ones at one or more of the C-2, C-6, C-22 and C-23 carbon atoms.	Brassinosteroids	18-21	nucleolin	Homo sapiens	213-217
11346939-6	2001	Sterol analyses of the bull-1 mutant indicated that bul1-1 is defective in the delta 7-sterol-C5-desaturation step leading to brassinosteroid biosynthesis.	Brassinosteroids	126-141	sterol 1	Arabidopsis thaliana	52-58
11346939-11	2001	Cellular characterization and rescue experiments with brassinosteroids demonstrated the involvement of the BUL1-1 protein in brassinosteroid-dependent plant growth processes.	Brassinosteroids	54-70	sterol 1	Arabidopsis thaliana	107-113
11346939-11	2001	Cellular characterization and rescue experiments with brassinosteroids demonstrated the involvement of the BUL1-1 protein in brassinosteroid-dependent plant growth processes.	Brassinosteroids	54-69	sterol 1	Arabidopsis thaliana	107-113
11346940-2	2001	Effects of brassinosteroids on microtubules and cell elongation in the bul1 mutant.	Brassinosteroids	11-27	sterol 1	Arabidopsis thaliana	71-75
11346940-7	2001	Molecular analyses showed that the microtubule reorganization observed in brassinosteroid-treated bul1-1 plants did not result either from an activation of tubulin gene expression, or from an increase in tubulin content, suggesting that a brassinosteroid-responsive pathway exists which allows microtubule nucleation/organization and cell elongation without activation of tubulin gene expression.	Brassinosteroids	74-89	sterol 1	Arabidopsis thaliana	98-102
11346940-7	2001	Molecular analyses showed that the microtubule reorganization observed in brassinosteroid-treated bul1-1 plants did not result either from an activation of tubulin gene expression, or from an increase in tubulin content, suggesting that a brassinosteroid-responsive pathway exists which allows microtubule nucleation/organization and cell elongation without activation of tubulin gene expression.	Brassinosteroids	239-254	sterol 1	Arabidopsis thaliana	98-102
11123807-6	2000	Induction was also found to occur in cells of a BR-insensitive mutant, bri1, suggesting that BR induces CycD3 transcription through a previously unknown signal pathway in plants.	Brassinosteroids	48-50	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	71-75
11123807-6	2000	Induction was also found to occur in cells of a BR-insensitive mutant, bri1, suggesting that BR induces CycD3 transcription through a previously unknown signal pathway in plants.	Brassinosteroids	48-50	CYCLIN D3;1	Arabidopsis thaliana	104-109
11123807-6	2000	Induction was also found to occur in cells of a BR-insensitive mutant, bri1, suggesting that BR induces CycD3 transcription through a previously unknown signal pathway in plants.	Brassinosteroids	93-95	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	71-75
11123807-6	2000	Induction was also found to occur in cells of a BR-insensitive mutant, bri1, suggesting that BR induces CycD3 transcription through a previously unknown signal pathway in plants.	Brassinosteroids	93-95	CYCLIN D3;1	Arabidopsis thaliana	104-109
10611382-0	1999	BAS1: A gene regulating brassinosteroid levels and light responsiveness in Arabidopsis.	Brassinosteroids	24-39	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-4
10875920-0	2000	Perception of brassinosteroids by the extracellular domain of the receptor kinase BRI1.	Brassinosteroids	14-30	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	82-86
10875920-4	2000	These results, which indicate that the extracellular domain of BRI1 perceives brassinosteroids, suggest a general signaling mechanism for the LRR receptor kinases of plants.	Brassinosteroids	78-94	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	63-67
10859167-1	2000	Here we report a novel Arabidopsis dwarf mutant, fackel-J79, whose adult morphology resembles that of brassinosteroid-deficient mutants but also displays distorted embryos, supernumerary cotyledons, multiple shoot meristems, and stunted roots.	Brassinosteroids	102-117	Ergosterol biosynthesis ERG4/ERG24 family	Arabidopsis thaliana	49-55
10886771-9	2000	Experiments with tomato seedlings showed that the localized BR-dependent growth response of the hypocotyl elongation zone was accompanied by a specific induction of Lin6 mRNA that is restricted to the corresponding tissues.	Brassinosteroids	60-62	acid invertase	Solanum lycopersicum	165-169
10872231-2	2000	The expression of the OPR3 gene is induced not only by a variety of stimuli, such as touch, wind, wounding, UV-light and application of detergent, but also by brassinosteroids.	Brassinosteroids	159-175	oxophytodienoate-reductase 3	Arabidopsis thaliana	22-26
10611382-2	1999	The adult phenotype of bas1-D phyB-4 double mutants mimics that of brassinosteroid biosynthetic and response mutants.	Brassinosteroids	67-82	Cytochrome P450 superfamily protein	Arabidopsis thaliana	23-27
10611382-3	1999	bas1-D phyB-4 has reduced levels of brassinosteroids and accumulates 26-hydroxybrassinolide in feeding experiments.	Brassinosteroids	36-52	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-4
10611382-6	1999	Seedlings with reduced BAS1 expression are hyperresponsive to brassinosteroids in a light-dependent manner and display reduced sensitivity to light under a variety of conditions.	Brassinosteroids	62-78	Cytochrome P450 superfamily protein	Arabidopsis thaliana	23-27
10069828-0	1999	The Arabidopsis dwarf1 mutant is defective in the conversion of 24-methylenecholesterol to campesterol in brassinosteroid biosynthesis.	Brassinosteroids	106-121	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	16-22
10398719-0	1999	Arabidopsis det2 is defective in the conversion of (24R)-24-methylcholest-4-En-3-one to (24R)-24-methyl-5alpha-cholestan-3-one in brassinosteroid biosynthesis.	Brassinosteroids	130-145	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	12-16
10398719-1	1999	Previously, we have shown that the Arabidopsis det2 (deetiolated2) mutant is defective in the biosynthesis of brassinosteroids (BR) and that DET2 (a steroid 5alpha-reductase) acts early in the proposed BR biosynthetic pathway.	Brassinosteroids	110-126	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	47-51
10398719-1	1999	Previously, we have shown that the Arabidopsis det2 (deetiolated2) mutant is defective in the biosynthesis of brassinosteroids (BR) and that DET2 (a steroid 5alpha-reductase) acts early in the proposed BR biosynthetic pathway.	Brassinosteroids	128-130	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	47-51
10398719-4	1999	The results of these studies indicate the early operating steps of BR biosynthesis as: campesterol --> 4-en-3beta-ol --> 4-en-3-one --> 3-one --> campestanol in Arabidopsis, with det2 deficient in the conversion of 4-en-3-one to 3-one.	Brassinosteroids	67-69	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	191-195
10557222-9	1999	The accumulation of biologically active BRs may result from the inability to utilize these active BRs, the inability to regulate BR biosynthesis in bri1 mutants, or both.	Brassinosteroids	40-42	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	148-152
10069828-3	1999	Feeding tests with brassinosteroid-biosynthetic intermediates revealed that dwf1 can be rescued by 22alpha-hydroxycampesterol and downstream intermediates in the brassinosteroid pathway.	Brassinosteroids	19-34	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	76-80
10069828-3	1999	Feeding tests with brassinosteroid-biosynthetic intermediates revealed that dwf1 can be rescued by 22alpha-hydroxycampesterol and downstream intermediates in the brassinosteroid pathway.	Brassinosteroids	162-177	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	76-80
10069828-4	1999	Analysis of the endogenous levels of brassinosteroid intermediates showed that 24-methylenecholesterol in dwf1 accumulates to 12 times the level of the wild type, whereas the level of campesterol is greatly diminished, indicating that the defective step is in C-24 reduction.	Brassinosteroids	37-52	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	106-110
10069828-7	1999	Our molecular characterization of dwf1 alleles, together with our biochemical data, suggest that the biosynthetic defect in dwf1 results in reduced synthesis of bioactive brassinosteroids, causing dwarfism.	Brassinosteroids	171-187	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	34-38
9990098-0	1999	The tomato DWARF enzyme catalyses C-6 oxidation in brassinosteroid biosynthesis.	Brassinosteroids	51-66	6-deoxocastasterone oxidase	Solanum lycopersicum	11-16
9990098-6	1999	To identify a substrate for the DWARF enzyme, exogenous application of BR intermediates to dx plants was carried out.	Brassinosteroids	71-73	6-deoxocastasterone oxidase	Solanum lycopersicum	32-37
9990098-12	1999	These data show that DWARF is involved in the C-6 oxidation in BR biosynthesis.	Brassinosteroids	63-65	6-deoxocastasterone oxidase	Solanum lycopersicum	21-26
10069828-7	1999	Our molecular characterization of dwf1 alleles, together with our biochemical data, suggest that the biosynthetic defect in dwf1 results in reduced synthesis of bioactive brassinosteroids, causing dwarfism.	Brassinosteroids	171-187	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	124-128
9927639-0	1999	The Arabidopsis dwf7/ste1 mutant is defective in the delta7 sterol C-5 desaturation step leading to brassinosteroid biosynthesis.	Brassinosteroids	100-115	sterol 1	Arabidopsis thaliana	16-20
9927639-0	1999	The Arabidopsis dwf7/ste1 mutant is defective in the delta7 sterol C-5 desaturation step leading to brassinosteroid biosynthesis.	Brassinosteroids	100-115	sterol 1	Arabidopsis thaliana	21-25
9927639-3	1999	Here, we present analysis of a novel BR biosynthetic locus, dwarf7 (dwf7).	Brassinosteroids	37-39	sterol 1	Arabidopsis thaliana	60-66
9927639-3	1999	Here, we present analysis of a novel BR biosynthetic locus, dwarf7 (dwf7).	Brassinosteroids	37-39	sterol 1	Arabidopsis thaliana	68-72
9927639-4	1999	Feeding studies with BR biosynthetic intermediates and analysis of endogenous levels of BR and sterol biosynthetic intermediates indicate that the defective step in dwf7-1 resides before the production of 24-methylenecholesterol in the sterol biosynthetic pathway.	Brassinosteroids	21-23	sterol 1	Arabidopsis thaliana	165-169
9927639-4	1999	Feeding studies with BR biosynthetic intermediates and analysis of endogenous levels of BR and sterol biosynthetic intermediates indicate that the defective step in dwf7-1 resides before the production of 24-methylenecholesterol in the sterol biosynthetic pathway.	Brassinosteroids	88-90	sterol 1	Arabidopsis thaliana	165-169
9761794-4	1998	In addition, we show that dim is deficient in brassinosteroids as well.	Brassinosteroids	46-62	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	26-29
9755157-10	1998	However, reduced KOR-mRNA levels were observed in det2, a mutant deficient for brassinosteroids.	Brassinosteroids	79-95	glycosyl hydrolase 9A1	Arabidopsis thaliana	17-20
9401120-0	1997	The Arabidopsis deetiolated2 mutant is blocked early in brassinosteroid biosynthesis.	Brassinosteroids	56-71	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	16-28
9675902-0	1998	Transcription of the Arabidopsis CPD gene, encoding a steroidogenic cytochrome P450, is negatively controlled by brassinosteroids.	Brassinosteroids	113-129	Cytochrome P450 superfamily protein	Arabidopsis thaliana	33-36
9675902-6	1998	Repression of CPD transcription by brassinosteroids is sensitive to the protein synthesis inhibitor cycloheximide, indicating a requirement for de novo synthesis of a regulatory factor.	Brassinosteroids	35-51	Cytochrome P450 superfamily protein	Arabidopsis thaliana	14-17
9490746-0	1998	The DWF4 gene of Arabidopsis encodes a cytochrome P450 that mediates multiple 22alpha-hydroxylation steps in brassinosteroid biosynthesis.	Brassinosteroids	109-124	Cytochrome P450 superfamily protein	Arabidopsis thaliana	4-8
9490746-2	1998	Dwarfism could be rescued by the application of brassinolide, suggesting that DWF4 plays a role in brassinosteroid (BR) biosynthesis.	Brassinosteroids	99-114	Cytochrome P450 superfamily protein	Arabidopsis thaliana	78-82
9490746-2	1998	Dwarfism could be rescued by the application of brassinolide, suggesting that DWF4 plays a role in brassinosteroid (BR) biosynthesis.	Brassinosteroids	116-118	Cytochrome P450 superfamily protein	Arabidopsis thaliana	78-82
9490746-9	1998	In fact, feeding studies utilizing BR intermediates showed that only 22alpha-hydroxylated BRs rescued the dwf4 phenotype, confirming that DWF4 acts as a 22alpha-hydroxylase.	Brassinosteroids	35-37	Cytochrome P450 superfamily protein	Arabidopsis thaliana	138-142
8612270-0	1996	Brassinosteroids rescue the deficiency of CYP90, a cytochrome P450, controlling cell elongation and de-etiolation in Arabidopsis.	Brassinosteroids	0-16	Cytochrome P450 superfamily protein	Arabidopsis thaliana	51-66
9446185-2	1997	No compound of the 12 tested brassinosteroids exerted higher inhibition of ATPase than digitoxin.	Brassinosteroids	29-45	dynein axonemal heavy chain 8	Homo sapiens	75-81
8754677-5	1996	The bri1 mutant showed multiple deficiencies in developmental pathways that could not be rescued by brassinosteroid treatment including a severely dwarfed stature; dark green, thickened leaves; males sterility; reduced apical dominance; and de-etiolation of dark-grown seedlings.	Brassinosteroids	100-115	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	4-8
8754677-7	1996	The multiple and dramatic effects of mutation of the BRI1 locus on development suggests that the BRI1 gene may play a critical role in brassinosteroid perception or signal transduction.	Brassinosteroids	135-150	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	53-57
8754677-7	1996	The multiple and dramatic effects of mutation of the BRI1 locus on development suggests that the BRI1 gene may play a critical role in brassinosteroid perception or signal transduction.	Brassinosteroids	135-150	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	97-101
34922335-0	2022	MYB42 inhibits hypocotyl cell elongation by coordinating brassinosteroid homeostasis and signaling in Arabidopsis thaliana.	Brassinosteroids	57-72	myb domain protein 42	Arabidopsis thaliana	0-5
33764637-0	2021	Protein farnesylation negatively regulates brassinosteroid signaling via reducing BES1 stability in Arabidopsis thaliana.	Brassinosteroids	43-58	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	82-86
33764637-4	2021	Previous studies demonstrated a role of farnesylation in BR biosynthesis via regulating the ER localization of a key bassinolide (BL) biosynthetic enzyme BR6ox2.	Brassinosteroids	57-59	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	154-160
33800127-4	2021	Brassinosteroids (BR) are a class of plant hormones that impact tolerance to various biotic and abiotic stresses and regulate cereal growth and fertility.	Brassinosteroids	0-16	chromosome 12 open reading frame 73	Homo sapiens	18-20
23956414-8	2013	Likewise, transient expression of ZmMPK5 enhanced BR-induced activities of the antioxidant defence enzymes SOD and APX in a ZmMAP65- 1a-dependent manner.	Brassinosteroids	50-52	MAP kinase 2	Zea mays	34-40
23956414-8	2013	Likewise, transient expression of ZmMPK5 enhanced BR-induced activities of the antioxidant defence enzymes SOD and APX in a ZmMAP65- 1a-dependent manner.	Brassinosteroids	50-52	superoxide dismutase	Zea mays	107-110
23956414-8	2013	Likewise, transient expression of ZmMPK5 enhanced BR-induced activities of the antioxidant defence enzymes SOD and APX in a ZmMAP65- 1a-dependent manner.	Brassinosteroids	50-52	APx1-Cytosolic Ascorbate Peroxidase	Zea mays	115-118
23956414-10	2013	These results suggest that BR-induced antioxidant defence in maize operates through the interaction of ZmMPK5 with ZmMAP65-1a.	Brassinosteroids	27-29	MAP kinase 2	Zea mays	103-109
34693527-4	2022	Here, we report that phytohormone brassinosteroid (BR) and redox signal hydrogen peroxide (H2 O2 ) interdependently promote periclinal division during root ground tissue maturation by regulating the activity of SHORT-ROOT (SHR), a master regulator of root growth and development.	Brassinosteroids	51-53	GRAS family transcription factor	Arabidopsis thaliana	223-226
33232670-4	2020	We reveal that AGO10 expression is precisely controlled temporally and spatially by auxin, brassinosteroids, and light to result in AM initiation only in the axils of leaves at a certain age.	Brassinosteroids	91-107	Stabilizer of iron transporter SufD / Polynucleotidyl transferase	Arabidopsis thaliana	15-20
7580251-5	1995	We determined that TCH4 expression is regulated by auxin and brassinosteroids, by environmental stimuli, and during development, by a 1-kb region.	Brassinosteroids	61-77	Xyloglucan endotransglucosylase/hydrolase family protein	Arabidopsis thaliana	19-23
34089602-2	2021	However, the regulatory mechanism of BRI1 in brassinosteroid (BR)-mediated signaling for shoot growth and wood formation in woody plant is largely unknown.	Brassinosteroids	45-60	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	37-41
34529936-1	2021	Brassinosteroids (BRs) play essential roles in growth and development in seed plants;1 disturbances in BR homeostasis lead to altered mitotic activity in meristems2,3 and organ boundaries4,5 and to changes in meristem determinacy.6 An intricate signaling cascade linking the perception of BRs at the plasma membrane to the regulation of master transcriptional regulators belonging to the BEH, for BES1 homologues, family7 has been described in great detail in model angiosperms.	Brassinosteroids	0-16	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	397-401
34718527-0	2022	Inhibition of 4-Hydroxyphenylpyruvate Dioxygenase expression by brassinosteroid reduces carotenoid accumulation in Arabidopsis.	Brassinosteroids	64-79	4-hydroxyphenylpyruvate dioxygenase	Arabidopsis thaliana	14-49
34948385-8	2021	Combined with a determination of the cellulose content, our results indicated that sucrose-induced BIN2 degradation led to the accumulation of BZR1 and the enhancement of cellulose synthesis, thereby promoting skotomorphogenesis, and that BIN2 is the converging node that integrates sugar and BR signaling.	Brassinosteroids	293-295	bridging integrator 2	Homo sapiens	99-103
34948385-8	2021	Combined with a determination of the cellulose content, our results indicated that sucrose-induced BIN2 degradation led to the accumulation of BZR1 and the enhancement of cellulose synthesis, thereby promoting skotomorphogenesis, and that BIN2 is the converging node that integrates sugar and BR signaling.	Brassinosteroids	293-295	bridging integrator 2	Homo sapiens	239-243
34449890-2	2021	Brassinosteroid (BR) and ethylene (ET) have overlapping functions in a wide range of developmental processes.	Brassinosteroids	0-15	chromosome 12 open reading frame 73	Homo sapiens	17-19
34436598-1	2021	Brassinosteroids (BRs) regulate plant growth, development and stress responses by activating the core transcription factor BRI1-EMS-SUPPRESSOR1 (BES1), whose degradation occurs through the proteasome and autophagy pathways.	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	123-127
34436598-1	2021	Brassinosteroids (BRs) regulate plant growth, development and stress responses by activating the core transcription factor BRI1-EMS-SUPPRESSOR1 (BES1), whose degradation occurs through the proteasome and autophagy pathways.	Brassinosteroids	0-16	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	145-149
34618046-0	2021	CALMODULIN-LIKE-38 and PEP1 RECEPTOR 2 integrate nitrate and brassinosteroid signals to regulate root growth.	Brassinosteroids	61-76	calmodulin-like 38	Arabidopsis thaliana	0-18
34618046-0	2021	CALMODULIN-LIKE-38 and PEP1 RECEPTOR 2 integrate nitrate and brassinosteroid signals to regulate root growth.	Brassinosteroids	61-76	PEP1 receptor 2	Arabidopsis thaliana	23-38
34618046-4	2021	CML38 and PEPR2 are transcriptionally induced by treatments of exogenous nitrate and BR.	Brassinosteroids	85-87	calmodulin-like 38	Arabidopsis thaliana	0-5
34618046-4	2021	CML38 and PEPR2 are transcriptionally induced by treatments of exogenous nitrate and BR.	Brassinosteroids	85-87	PEP1 receptor 2	Arabidopsis thaliana	10-15
34782771-3	2021	Here we tackled this question by studying the effect of brassinosteroid (BR) signalling on the structure of the root meristem.	Brassinosteroids	56-71	chromosome 12 open reading frame 73	Homo sapiens	73-75
34544007-8	2021	Together, this study demonstrates a novel role of ZmPgb1.1 in modulating plant performance to cold stress, and integrates the ZmPgb1.1 response in a model requiring NO and BR to alleviate oxidative stress through ZmMPK5.	Brassinosteroids	172-174	MAP kinase 2	Zea mays	213-219
34089602-2	2021	However, the regulatory mechanism of BRI1 in brassinosteroid (BR)-mediated signaling for shoot growth and wood formation in woody plant is largely unknown.	Brassinosteroids	62-64	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	37-41
34059919-8	2021	At the biochemical level, BEH3 showed weak transcriptional repressor activity and functioned antagonistically to other BES/BZR members by competing for binding to the brassinosteroid (BR) response element.	Brassinosteroids	167-182	BES1/BZR1 homolog 3	Arabidopsis thaliana	26-30
34622177-0	2021	Erratum: Brassinosteroids Regulate Circadian Oscillation via the BES1/TPL-CCA1/LHY Module in Arabidopsis thaliana.	Brassinosteroids	9-25	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	65-69
34622177-0	2021	Erratum: Brassinosteroids Regulate Circadian Oscillation via the BES1/TPL-CCA1/LHY Module in Arabidopsis thaliana.	Brassinosteroids	9-25	Transducin family protein / WD-40 repeat family protein	Arabidopsis thaliana	70-78
34622177-0	2021	Erratum: Brassinosteroids Regulate Circadian Oscillation via the BES1/TPL-CCA1/LHY Module in Arabidopsis thaliana.	Brassinosteroids	9-25	Homeodomain-like superfamily protein	Arabidopsis thaliana	79-82
34059919-8	2021	At the biochemical level, BEH3 showed weak transcriptional repressor activity and functioned antagonistically to other BES/BZR members by competing for binding to the brassinosteroid (BR) response element.	Brassinosteroids	184-186	BES1/BZR1 homolog 3	Arabidopsis thaliana	26-30
35524409-0	2022	Brassinosteroids enhance salicylic acid-mediated immune responses by inhibiting BIN2 phosphorylation of clade I TGA transcription factors in Arabidopsis.	Brassinosteroids	0-16	Protein kinase superfamily protein	Arabidopsis thaliana	80-84
34385302-5	2021	Using a photoconvertible fluorescent protein, Kaede, as a living tag to distinguish newly synthesized BZR1 from existing BZR1, we demonstrated that BR treatment recruits cytosolic BZR1 to the nucleus, which could explain the fast responses of plants to BR.	Brassinosteroids	148-150	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	102-106
34385302-5	2021	Using a photoconvertible fluorescent protein, Kaede, as a living tag to distinguish newly synthesized BZR1 from existing BZR1, we demonstrated that BR treatment recruits cytosolic BZR1 to the nucleus, which could explain the fast responses of plants to BR.	Brassinosteroids	148-150	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	121-125
34385302-5	2021	Using a photoconvertible fluorescent protein, Kaede, as a living tag to distinguish newly synthesized BZR1 from existing BZR1, we demonstrated that BR treatment recruits cytosolic BZR1 to the nucleus, which could explain the fast responses of plants to BR.	Brassinosteroids	148-150	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	180-184
34116634-1	2021	BACKGROUND: Brassinosteroid-insensitive 1 suppressor 1 (BRS1) is a serine carboxypeptidase that mediates brassinosteroid signaling and participates in multiple developmental processes in Arabidopsis.	Brassinosteroids	105-120	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	12-54
34116634-1	2021	BACKGROUND: Brassinosteroid-insensitive 1 suppressor 1 (BRS1) is a serine carboxypeptidase that mediates brassinosteroid signaling and participates in multiple developmental processes in Arabidopsis.	Brassinosteroids	105-120	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	56-60
34386030-2	2021	Here, we demonstrate that AIF2 negatively modulates brassinosteroid (BR)-induced, BRASSINAZOLE RESISTANT 1 (BZR1)-mediated pollen and seed formation.	Brassinosteroids	52-67	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	26-30
34386030-2	2021	Here, we demonstrate that AIF2 negatively modulates brassinosteroid (BR)-induced, BRASSINAZOLE RESISTANT 1 (BZR1)-mediated pollen and seed formation.	Brassinosteroids	69-71	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	26-30
34386030-9	2021	Contrarily, sucrose and BR repressed ectopic accumulation of AIF2, thereby increasing silique length and the number of seeds.	Brassinosteroids	24-26	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	61-65
34386030-10	2021	Taken together, we propose that AIF2 is negatively involved in pollen development and seed formation, and that sucrose- and BR-induced repression of AIF2 positively promotes pollen production and seed formation in Arabidopsis.	Brassinosteroids	124-126	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	32-36
34386030-10	2021	Taken together, we propose that AIF2 is negatively involved in pollen development and seed formation, and that sucrose- and BR-induced repression of AIF2 positively promotes pollen production and seed formation in Arabidopsis.	Brassinosteroids	124-126	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	149-153
35524409-4	2022	Here we showed that the steroid plant hormone brassinosteroid (BR) promotes SA responses by inactivating BR-INSENSITIVE 2 (BIN2), which inhibits the redox-sensitive clade I TGAs in Arabidopsis.	Brassinosteroids	46-61	Protein kinase superfamily protein	Arabidopsis thaliana	105-121
35628619-5	2022	sbi2 restored the sensitivity of brassinosteroid receptor mutants bri1-5, bri1-9, and bri1-235 with ER-trapped BRI1 to brassinosteroids.	Brassinosteroids	119-135	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	66-70
35139225-9	2022	This study demonstrates that C3H15-mediated BR signaling may be parallel to, or even attenuate, the dominant BZR1 and BES1 signaling pathways to control cell elongation.	Brassinosteroids	44-46	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	109-113
35139225-9	2022	This study demonstrates that C3H15-mediated BR signaling may be parallel to, or even attenuate, the dominant BZR1 and BES1 signaling pathways to control cell elongation.	Brassinosteroids	44-46	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	118-122
35524409-4	2022	Here we showed that the steroid plant hormone brassinosteroid (BR) promotes SA responses by inactivating BR-INSENSITIVE 2 (BIN2), which inhibits the redox-sensitive clade I TGAs in Arabidopsis.	Brassinosteroids	46-61	Protein kinase superfamily protein	Arabidopsis thaliana	123-127
35524409-4	2022	Here we showed that the steroid plant hormone brassinosteroid (BR) promotes SA responses by inactivating BR-INSENSITIVE 2 (BIN2), which inhibits the redox-sensitive clade I TGAs in Arabidopsis.	Brassinosteroids	63-65	Protein kinase superfamily protein	Arabidopsis thaliana	105-121
35524409-4	2022	Here we showed that the steroid plant hormone brassinosteroid (BR) promotes SA responses by inactivating BR-INSENSITIVE 2 (BIN2), which inhibits the redox-sensitive clade I TGAs in Arabidopsis.	Brassinosteroids	63-65	Protein kinase superfamily protein	Arabidopsis thaliana	123-127
35615132-0	2022	MdJa2 Participates in the Brassinosteroid Signaling Pathway to Regulate the Synthesis of Anthocyanin and Proanthocyanidin in Red-Fleshed Apple.	Brassinosteroids	26-41	MADS-box protein JOINTLESS	Malus domestica	0-5
35628619-5	2022	sbi2 restored the sensitivity of brassinosteroid receptor mutants bri1-5, bri1-9, and bri1-235 with ER-trapped BRI1 to brassinosteroids.	Brassinosteroids	119-135	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	74-78
35628619-5	2022	sbi2 restored the sensitivity of brassinosteroid receptor mutants bri1-5, bri1-9, and bri1-235 with ER-trapped BRI1 to brassinosteroids.	Brassinosteroids	119-135	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	86-90
35628619-5	2022	sbi2 restored the sensitivity of brassinosteroid receptor mutants bri1-5, bri1-9, and bri1-235 with ER-trapped BRI1 to brassinosteroids.	Brassinosteroids	119-135	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	111-115
35457060-1	2022	The BES1 (BRI1-EMSSUPPRESSOR1) gene family is a unique class of transcription factors that play dynamic roles in the Brassinosteroids (BRs) signaling pathway.	Brassinosteroids	117-133	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	4-8
35457060-1	2022	The BES1 (BRI1-EMSSUPPRESSOR1) gene family is a unique class of transcription factors that play dynamic roles in the Brassinosteroids (BRs) signaling pathway.	Brassinosteroids	117-133	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	10-29
35457060-1	2022	The BES1 (BRI1-EMSSUPPRESSOR1) gene family is a unique class of transcription factors that play dynamic roles in the Brassinosteroids (BRs) signaling pathway.	Brassinosteroids	135-138	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	4-8
35457060-1	2022	The BES1 (BRI1-EMSSUPPRESSOR1) gene family is a unique class of transcription factors that play dynamic roles in the Brassinosteroids (BRs) signaling pathway.	Brassinosteroids	135-138	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	10-29
33963401-5	2021	Expression of HBI1 and BEE2 was induced in response to BR and GA treatment.	Brassinosteroids	55-57	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	14-18
34020507-0	2021	Brassinosteroids inhibit miRNA-mediated translational repression by decreasing AGO1 on the endoplasmic reticulum.	Brassinosteroids	0-16	Stabilizer of iron transporter SufD / Polynucleotidyl transferase	Arabidopsis thaliana	79-83
34020507-5	2021	Here, we show that the plant hormones brassinosteroids (BRs) inhibit miRNA-mediated translational repression by negatively regulating the distribution of AGO1 at the ER in Arabidopsis thaliana.	Brassinosteroids	38-54	Stabilizer of iron transporter SufD / Polynucleotidyl transferase	Arabidopsis thaliana	154-158
34020507-5	2021	Here, we show that the plant hormones brassinosteroids (BRs) inhibit miRNA-mediated translational repression by negatively regulating the distribution of AGO1 at the ER in Arabidopsis thaliana.	Brassinosteroids	56-59	Stabilizer of iron transporter SufD / Polynucleotidyl transferase	Arabidopsis thaliana	154-158
33980131-0	2021	Endogenous level of abscisic acid down-regulated by brassinosteroids signaling via BZR1 to control the growth of Arabidopsis thaliana.	Brassinosteroids	52-68	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	83-87
35629883-5	2022	In turn, brassinosteroid insensitive 1 (BRI1)-associated receptor kinase 1 (BAK1) is a well-established co-receptor for several defence-related PRRs in plants.	Brassinosteroids	9-24	BRI1-associated receptor kinase	Arabidopsis thaliana	76-80
35245283-9	2022	Furthermore, brassinosteroid influences the late ovule initiation through positively regulating PIN3 expression.	Brassinosteroids	13-28	Auxin efflux carrier family protein	Arabidopsis thaliana	96-100
33963401-5	2021	Expression of HBI1 and BEE2 was induced in response to BR and GA treatment.	Brassinosteroids	55-57	BR enhanced expression 2	Arabidopsis thaliana	23-27
33963401-6	2021	In addition, HBI1 or BEE2 overexpressing Arabidopsis plants are less sensitive to the BR biosynthesis inhibitor, brassinazole, and the GA biosynthesis inhibitor, paclobutrazol.	Brassinosteroids	86-88	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	13-17
33963401-6	2021	In addition, HBI1 or BEE2 overexpressing Arabidopsis plants are less sensitive to the BR biosynthesis inhibitor, brassinazole, and the GA biosynthesis inhibitor, paclobutrazol.	Brassinosteroids	86-88	BR enhanced expression 2	Arabidopsis thaliana	21-25
33964457-4	2021	Using the RiD-receptors, we demonstrated that the rapamycin-mediated association of chimeric cytosolic kinase domains from the BRI1/BAK1 receptor/co-receptor, but not the BRI1/BRI1 or BAK1/BAK1 homodimer, is sufficient to activate downstream brassinosteroid signaling and physiological responses and that the engineered RiD-FLS2/BAK1 activates flagellin-22-mediated immune signaling and responses.	Brassinosteroids	242-257	BCL2 antagonist/killer 1	Homo sapiens	132-136
33871651-4	2021	In the light, NF-YCs inhibit BR biosynthesis by directly targeting the promoter of the BR biosynthesis gene BR6ox2 and repressing its transcription.	Brassinosteroids	29-31	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	108-114
33871651-4	2021	In the light, NF-YCs inhibit BR biosynthesis by directly targeting the promoter of the BR biosynthesis gene BR6ox2 and repressing its transcription.	Brassinosteroids	87-89	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	108-114
33098207-0	2021	Overexpression of GmMYB14 improves high-density yield and drought tolerance through regulating plant architecture mediated by the brassinosteroid pathway.	Brassinosteroids	130-145	transcription factor MYB63	Glycine max	18-25
33868337-0	2021	Seed-Specific Expression of Arabidopsis AtCYP85A2 Produces Biologically Active Brassinosteroids Such as Castasterone and Brassinolide to Improve Grain Yield and Quality in Seeds of Brachypodium Distachyon.	Brassinosteroids	79-95	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	40-49
33098207-7	2021	Indeed, GmMYB14-OX plants showed reduced endogenous BR contents, while exogenous application of brassinolide could partly rescue the phenotype of GmMYB14-OX plants.	Brassinosteroids	52-54	transcription factor MYB63	Glycine max	8-15
33967467-9	2021	Additionally, NtBRI1, NtBIN2, and NtBES1 are upregulated showing that the brassinosteroid signaling pathway is activated.	Brassinosteroids	74-89	systemin receptor SR160	Nicotiana tabacum	14-20
33098207-10	2021	GmBEN1 expression was also up-regulated in the leaves of GmMYB14-OX plants under polyethylene glycol treatment, indicating that the GmBEN1-mediated reduction of BR level under stress also contributed to drought/osmotic stress tolerance of the transgenic plants.	Brassinosteroids	161-163	transcription factor MYB63	Glycine max	57-64
33722761-5	2021	Two class A AUXIN RESPONSE FACTORs (ARFs), ARF6 and ARF8, activate the transcription of DWARF4, which encodes a key brassinosteroid (BR) biosynthetic enzyme.	Brassinosteroids	116-131	auxin response factor 6	Arabidopsis thaliana	43-47
33722761-5	2021	Two class A AUXIN RESPONSE FACTORs (ARFs), ARF6 and ARF8, activate the transcription of DWARF4, which encodes a key brassinosteroid (BR) biosynthetic enzyme.	Brassinosteroids	116-131	auxin response factor 8	Arabidopsis thaliana	52-56
33722761-5	2021	Two class A AUXIN RESPONSE FACTORs (ARFs), ARF6 and ARF8, activate the transcription of DWARF4, which encodes a key brassinosteroid (BR) biosynthetic enzyme.	Brassinosteroids	116-131	Cytochrome P450 superfamily protein	Arabidopsis thaliana	88-94
33722761-5	2021	Two class A AUXIN RESPONSE FACTORs (ARFs), ARF6 and ARF8, activate the transcription of DWARF4, which encodes a key brassinosteroid (BR) biosynthetic enzyme.	Brassinosteroids	133-135	auxin response factor 6	Arabidopsis thaliana	43-47
33722761-5	2021	Two class A AUXIN RESPONSE FACTORs (ARFs), ARF6 and ARF8, activate the transcription of DWARF4, which encodes a key brassinosteroid (BR) biosynthetic enzyme.	Brassinosteroids	133-135	auxin response factor 8	Arabidopsis thaliana	52-56
33722761-5	2021	Two class A AUXIN RESPONSE FACTORs (ARFs), ARF6 and ARF8, activate the transcription of DWARF4, which encodes a key brassinosteroid (BR) biosynthetic enzyme.	Brassinosteroids	133-135	Cytochrome P450 superfamily protein	Arabidopsis thaliana	88-94
33683399-0	2021	Identification of a putative candidate gene encoding 7-dehydrocholesterol reductase involved in brassinosteroids biosynthesis for compact plant architecture in Cucumber (Cucumis sativus L.).	Brassinosteroids	96-112	7-dehydrocholesterol reductase	Cucumis sativus	53-83
33247718-11	2021	Importantly, chimeric AtBRI1 replaced with the BR-binding domain of PaBRL1 complemented Atbri1 phenotypes.	Brassinosteroids	24-26	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	88-94
33529338-9	2021	Overexpression of BEH3 results in an osmotic stress-sensitive phenotype, which is reversed by exogenous BR application.	Brassinosteroids	104-106	BES1/BZR1 homolog 3	Arabidopsis thaliana	18-22
33258709-5	2021	ACO2 expression was increased in det2, a brassinosteroid (BR)-deficient mutant; however, it was decreased in bes1-D, a brassinosteroid insensitive 1-EMS-suppressor 1 (BES1)-dominant mutant.	Brassinosteroids	41-56	ACC oxidase 2	Arabidopsis thaliana	0-4
33258709-5	2021	ACO2 expression was increased in det2, a brassinosteroid (BR)-deficient mutant; however, it was decreased in bes1-D, a brassinosteroid insensitive 1-EMS-suppressor 1 (BES1)-dominant mutant.	Brassinosteroids	58-60	ACC oxidase 2	Arabidopsis thaliana	0-4
33491178-0	2021	Two ATAF transcription factors ANAC102 and ATAF1 contribute to the suppression of cytochrome P450-mediated brassinosteroid catabolism in Arabidopsis.	Brassinosteroids	107-122	NAC domain containing protein 102	Arabidopsis thaliana	31-38
33491178-0	2021	Two ATAF transcription factors ANAC102 and ATAF1 contribute to the suppression of cytochrome P450-mediated brassinosteroid catabolism in Arabidopsis.	Brassinosteroids	107-122	NAC (No Apical Meristem) domain transcriptional regulator superfamily protein	Arabidopsis thaliana	43-48
33491178-0	2021	Two ATAF transcription factors ANAC102 and ATAF1 contribute to the suppression of cytochrome P450-mediated brassinosteroid catabolism in Arabidopsis.	Brassinosteroids	107-122	CYP702A7P	Arabidopsis thaliana	82-97
33491178-1	2021	PHYB ACTIVATION TAGGED SUPPRESSOR 1 (BAS1) and SUPPRESSOR OF PHYB-4 7 (SOB7) are two cytochrome P450 enzymes that inactivate brassinosteroids (BRs) in Arabidopsis.	Brassinosteroids	125-141	Cytochrome P450 superfamily protein	Arabidopsis thaliana	37-41
33491178-1	2021	PHYB ACTIVATION TAGGED SUPPRESSOR 1 (BAS1) and SUPPRESSOR OF PHYB-4 7 (SOB7) are two cytochrome P450 enzymes that inactivate brassinosteroids (BRs) in Arabidopsis.	Brassinosteroids	125-141	cytochrome p450 72c1	Arabidopsis thaliana	47-69
33491178-1	2021	PHYB ACTIVATION TAGGED SUPPRESSOR 1 (BAS1) and SUPPRESSOR OF PHYB-4 7 (SOB7) are two cytochrome P450 enzymes that inactivate brassinosteroids (BRs) in Arabidopsis.	Brassinosteroids	125-141	cytochrome p450 72c1	Arabidopsis thaliana	71-75
33491178-1	2021	PHYB ACTIVATION TAGGED SUPPRESSOR 1 (BAS1) and SUPPRESSOR OF PHYB-4 7 (SOB7) are two cytochrome P450 enzymes that inactivate brassinosteroids (BRs) in Arabidopsis.	Brassinosteroids	125-141	CYP702A7P	Arabidopsis thaliana	85-100
33491178-1	2021	PHYB ACTIVATION TAGGED SUPPRESSOR 1 (BAS1) and SUPPRESSOR OF PHYB-4 7 (SOB7) are two cytochrome P450 enzymes that inactivate brassinosteroids (BRs) in Arabidopsis.	Brassinosteroids	143-146	Cytochrome P450 superfamily protein	Arabidopsis thaliana	37-41
33491178-1	2021	PHYB ACTIVATION TAGGED SUPPRESSOR 1 (BAS1) and SUPPRESSOR OF PHYB-4 7 (SOB7) are two cytochrome P450 enzymes that inactivate brassinosteroids (BRs) in Arabidopsis.	Brassinosteroids	143-146	cytochrome p450 72c1	Arabidopsis thaliana	47-69
33491178-1	2021	PHYB ACTIVATION TAGGED SUPPRESSOR 1 (BAS1) and SUPPRESSOR OF PHYB-4 7 (SOB7) are two cytochrome P450 enzymes that inactivate brassinosteroids (BRs) in Arabidopsis.	Brassinosteroids	143-146	cytochrome p450 72c1	Arabidopsis thaliana	71-75
33491178-1	2021	PHYB ACTIVATION TAGGED SUPPRESSOR 1 (BAS1) and SUPPRESSOR OF PHYB-4 7 (SOB7) are two cytochrome P450 enzymes that inactivate brassinosteroids (BRs) in Arabidopsis.	Brassinosteroids	143-146	CYP702A7P	Arabidopsis thaliana	85-100
33352948-3	2020	BRASSINOSTEROIDS INSENSITIVE 2 (BIN2), glycogen synthase kinase 3 (GSK3) like-kinase, negatively regulates BZR1/BES1 transcriptional activity through phosphorylation-dependent cytosolic retention and shuttling.	Brassinosteroids	0-16	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	107-111
33352948-3	2020	BRASSINOSTEROIDS INSENSITIVE 2 (BIN2), glycogen synthase kinase 3 (GSK3) like-kinase, negatively regulates BZR1/BES1 transcriptional activity through phosphorylation-dependent cytosolic retention and shuttling.	Brassinosteroids	0-16	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	112-116
33324437-6	2020	JMJs remove the repressive histone marks from the BRASSINAZOLE RESISTANT1 (BZR1) locus for its activation to balance ABA and BR signaling pathways.	Brassinosteroids	50-52	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	75-79
32611786-0	2020	The BADH acyltransferase BIA1 uses acetyl-CoA for catabolic inactivation of brassinosteroids.	Brassinosteroids	76-92	tripartite motif containing 11	Homo sapiens	25-29
33133168-1	2020	BRASSINOSTEROID INSENSITIVE1-EMS-suppressor 1 (BES1) is an essential regulator downstream of brassinosteroid signaling and plays important roles in plant stress response, growth, and development.	Brassinosteroids	0-15	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	47-51
33133168-1	2020	BRASSINOSTEROID INSENSITIVE1-EMS-suppressor 1 (BES1) is an essential regulator downstream of brassinosteroid signaling and plays important roles in plant stress response, growth, and development.	Brassinosteroids	93-108	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	47-51
32239656-0	2020	SHY2 as a node in the regulation of root meristem development by auxin, brassinosteroids, and cytokinin.	Brassinosteroids	72-88	AUX/IAA transcriptional regulator family protein	Arabidopsis thaliana	0-4
32239656-4	2020	We found that BR increases root meristem size by up-regulating expression of the PINFORMED 7 (PIN7) gene and down-regulating expression of the SHY2 gene.	Brassinosteroids	14-16	AUX/IAA transcriptional regulator family protein	Arabidopsis thaliana	143-147
33113884-9	2020	Furthermore, the prt6 mutant displayed increased sensitivity to ethylene and brassinosteroids, which can suppress Na+ uptake and promote the expression of stress-responsive genes.	Brassinosteroids	77-93	proteolysis 6	Arabidopsis thaliana	17-21
33082970-4	2020	We then generated transgenic lines overexpressing or silencing SlCYP90B3, which encodes a cytochrome P450 monooxygenase that catalyzes the rate-limiting step of BR synthesis.	Brassinosteroids	161-163	cytochrome P450 90B3	Solanum lycopersicum	63-72
33082970-8	2020	Taken together, these results increase our understanding of the involvement of SlCYP90B3 in bioactive BR biosynthesis as well as fruit ripening in tomato, thus making SlCYP90B3 a target gene for improvement of visual, nutritional and flavor qualities of tomato fruits with no yield penalty.	Brassinosteroids	102-104	cytochrome P450 90B3	Solanum lycopersicum	79-88
32947126-0	2020	Brassinosteroids Regulate Circadian Oscillation via the BES1/TPL-CCA1/LHY Module in Arabidopsisthaliana.	Brassinosteroids	0-16	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	56-60
32947126-0	2020	Brassinosteroids Regulate Circadian Oscillation via the BES1/TPL-CCA1/LHY Module in Arabidopsisthaliana.	Brassinosteroids	0-16	Transducin family protein / WD-40 repeat family protein	Arabidopsis thaliana	61-64
32947126-0	2020	Brassinosteroids Regulate Circadian Oscillation via the BES1/TPL-CCA1/LHY Module in Arabidopsisthaliana.	Brassinosteroids	0-16	circadian clock associated 1	Arabidopsis thaliana	65-69
32947126-0	2020	Brassinosteroids Regulate Circadian Oscillation via the BES1/TPL-CCA1/LHY Module in Arabidopsisthaliana.	Brassinosteroids	0-16	Homeodomain-like superfamily protein	Arabidopsis thaliana	70-73
32947126-5	2020	The repression of CCA1 and LHY by BR treatment, which occurred during the night, was compromised in bes1-ko and tpl-8 mutants.	Brassinosteroids	34-36	circadian clock associated 1	Arabidopsis thaliana	18-22
32947126-5	2020	The repression of CCA1 and LHY by BR treatment, which occurred during the night, was compromised in bes1-ko and tpl-8 mutants.	Brassinosteroids	34-36	Homeodomain-like superfamily protein	Arabidopsis thaliana	27-30
32947126-5	2020	The repression of CCA1 and LHY by BR treatment, which occurred during the night, was compromised in bes1-ko and tpl-8 mutants.	Brassinosteroids	34-36	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	100-104
32947126-5	2020	The repression of CCA1 and LHY by BR treatment, which occurred during the night, was compromised in bes1-ko and tpl-8 mutants.	Brassinosteroids	34-36	Transducin family protein / WD-40 repeat family protein	Arabidopsis thaliana	112-115
32669036-3	2020	In comparison with wild-type, under dehydration conditions, the expression levels of genes related to photosynthesis and the metabolism of glucosinolates and trehalose were significantly changed in both d14-1 and kai2-2 mutant plants, whereas the transcript levels of genes related to the metabolism of cytokinins and brassinosteroids were significantly altered in the d14-1 mutant plants only.	Brassinosteroids	318-334	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	213-217
32009278-0	2020	Brassinosteroids regulate outer ovule integument growth in part via the control of INNER NO OUTER by BRASSINOZOLE-RESISTANT family transcription factors.	Brassinosteroids	0-16	Plant-specific transcription factor YABBY family protein	Arabidopsis thaliana	26-31
32786402-1	2020	Brassinosteroid insensitive1 (BRI1), a leucine-rich repeat receptor kinase, is responsible for the perception of the brassinosteroid (BR) phytohormone in plants.	Brassinosteroids	0-15	BRI1	Hordeum vulgare	30-34
32009278-0	2020	Brassinosteroids regulate outer ovule integument growth in part via the control of INNER NO OUTER by BRASSINOZOLE-RESISTANT family transcription factors.	Brassinosteroids	0-16	Plant-specific transcription factor YABBY family protein	Arabidopsis thaliana	83-97
32009278-5	2020	Increased INO expression due to overexpression or increased transcriptional activity of BZR1 in the mutant alleviated the outer integument growth defect in bri1-116 ovules, suggesting that BRs regulate outer integument growth partially via BZR1-mediated transcriptional regulation of INO.	Brassinosteroids	189-192	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	88-92
32009278-5	2020	Increased INO expression due to overexpression or increased transcriptional activity of BZR1 in the mutant alleviated the outer integument growth defect in bri1-116 ovules, suggesting that BRs regulate outer integument growth partially via BZR1-mediated transcriptional regulation of INO.	Brassinosteroids	189-192	Plant-specific transcription factor YABBY family protein	Arabidopsis thaliana	202-207
32009278-7	2020	Together, our findings establish a new role for BRs in regulating ovule development and suggest that BZR1 family transcription factors might regulate outer integument growth through both BRI1-dependent and BRI1-independent pathways.	Brassinosteroids	48-51	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	101-105
32487564-3	2020	Etiolated seedlings of the brassinosteroids-deficient det2-1 (de-etiolated2) mutant accumulated excess protochlorophyllide, resulting in photo-oxidative damage upon exposure to light.	Brassinosteroids	27-43	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	62-75
32333772-13	2020	Our data collectively suggest that light activates the expression of BR biosynthesis genes in the hook region via a phytochrome-signaling pathway and HY5 and that BR biosynthesis is essential for hook opening and petiole development during photomorphogenesis.	Brassinosteroids	69-71	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	150-153
32664862-5	2020	In this study, we found that B1L interacts with TRANSTHYRETIN-LIKE (TTL) protein, which is involved in brassinosteroid (BR)-mediated plant growth and catalyses the synthesis of S-allantoin, and both proteins participate in modulating plant growth and cold tolerance.	Brassinosteroids	103-118	coiled coil protein	Arabidopsis thaliana	48-66
32664862-5	2020	In this study, we found that B1L interacts with TRANSTHYRETIN-LIKE (TTL) protein, which is involved in brassinosteroid (BR)-mediated plant growth and catalyses the synthesis of S-allantoin, and both proteins participate in modulating plant growth and cold tolerance.	Brassinosteroids	103-118	coiled coil protein	Arabidopsis thaliana	68-71
32664862-5	2020	In this study, we found that B1L interacts with TRANSTHYRETIN-LIKE (TTL) protein, which is involved in brassinosteroid (BR)-mediated plant growth and catalyses the synthesis of S-allantoin, and both proteins participate in modulating plant growth and cold tolerance.	Brassinosteroids	120-122	coiled coil protein	Arabidopsis thaliana	48-66
32664862-5	2020	In this study, we found that B1L interacts with TRANSTHYRETIN-LIKE (TTL) protein, which is involved in brassinosteroid (BR)-mediated plant growth and catalyses the synthesis of S-allantoin, and both proteins participate in modulating plant growth and cold tolerance.	Brassinosteroids	120-122	coiled coil protein	Arabidopsis thaliana	68-71
32540000-0	2020	A defect in BRI1-EMS-SUPPRESSOR 1 (bes1)-mediated brassinosteroid signaling increases photoinhibition and photo-oxidative stress during heat stress in Arabidopsis.	Brassinosteroids	50-65	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	12-33
32540000-0	2020	A defect in BRI1-EMS-SUPPRESSOR 1 (bes1)-mediated brassinosteroid signaling increases photoinhibition and photo-oxidative stress during heat stress in Arabidopsis.	Brassinosteroids	50-65	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	35-39
32540004-3	2020	The membrane-localized BR signaling receptor, BRASSINOSTEROID INSENSITIVE1 (BRI1) binds directly to its ligand and initiates series of signaling events that led to the activation of BR transcriptional regulators, BRASSINAZOLE RESISTANT1 (BZR1) and BRI1-ETHYL METHANESULFONATE-SUPPRESSOR1 (BES1/BZR2) to regulate the cellular processes.	Brassinosteroids	46-61	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	76-80
32540004-3	2020	The membrane-localized BR signaling receptor, BRASSINOSTEROID INSENSITIVE1 (BRI1) binds directly to its ligand and initiates series of signaling events that led to the activation of BR transcriptional regulators, BRASSINAZOLE RESISTANT1 (BZR1) and BRI1-ETHYL METHANESULFONATE-SUPPRESSOR1 (BES1/BZR2) to regulate the cellular processes.	Brassinosteroids	46-61	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	213-236
32540004-3	2020	The membrane-localized BR signaling receptor, BRASSINOSTEROID INSENSITIVE1 (BRI1) binds directly to its ligand and initiates series of signaling events that led to the activation of BR transcriptional regulators, BRASSINAZOLE RESISTANT1 (BZR1) and BRI1-ETHYL METHANESULFONATE-SUPPRESSOR1 (BES1/BZR2) to regulate the cellular processes.	Brassinosteroids	46-61	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	248-252
32774340-0	2020	Corrigendum: Arabidopsis G-Protein beta Subunit AGB1 Interacts With BES1 to Regulate Brassinosteroid Signaling and Cell Elongation.	Brassinosteroids	85-100	GTP binding protein beta 1	Arabidopsis thaliana	48-52
32774340-0	2020	Corrigendum: Arabidopsis G-Protein beta Subunit AGB1 Interacts With BES1 to Regulate Brassinosteroid Signaling and Cell Elongation.	Brassinosteroids	85-100	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	68-72
32193788-6	2020	GhMPK6 maintains a high phosphorylation level in elongating fibers, and its phosphorylation was enhanced in fibers by phytohormones brassinosteroid (BR), ethylene and indole-3-acetic acid (IAA).	Brassinosteroids	149-151	mitogen-activated protein kinase homolog D5	Gossypium hirsutum	0-6
32609718-0	2020	Brassinosteroids regulate root meristem development by mediating BIN2-UPB1 module in Arabidopsis.	Brassinosteroids	0-16	Protein kinase superfamily protein	Arabidopsis thaliana	65-69
32609718-0	2020	Brassinosteroids regulate root meristem development by mediating BIN2-UPB1 module in Arabidopsis.	Brassinosteroids	0-16	transcription factor UPBEAT protein	Arabidopsis thaliana	70-74
32109396-0	2020	SUMO Conjugation to BZR1 Enables Brassinosteroid Signaling to Integrate Environmental Cues to Shape Plant Growth.	Brassinosteroids	33-48	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	20-24
32113680-1	2020	Calcium/calmodulin-dependent protein kinase (CCaMK) has been shown to play important roles in brassinosteroid (BR)-induced antioxidant defense and enhancing the tolerance of plants to drought stress.	Brassinosteroids	94-109	calcium dependent protein kinase 1	Zea mays	0-43
32113680-1	2020	Calcium/calmodulin-dependent protein kinase (CCaMK) has been shown to play important roles in brassinosteroid (BR)-induced antioxidant defense and enhancing the tolerance of plants to drought stress.	Brassinosteroids	94-109	calcium dependent protein kinase 1	Zea mays	45-50
32113680-1	2020	Calcium/calmodulin-dependent protein kinase (CCaMK) has been shown to play important roles in brassinosteroid (BR)-induced antioxidant defense and enhancing the tolerance of plants to drought stress.	Brassinosteroids	111-113	calcium dependent protein kinase 1	Zea mays	0-43
32113680-1	2020	Calcium/calmodulin-dependent protein kinase (CCaMK) has been shown to play important roles in brassinosteroid (BR)-induced antioxidant defense and enhancing the tolerance of plants to drought stress.	Brassinosteroids	111-113	calcium dependent protein kinase 1	Zea mays	45-50
32113680-5	2020	The transient gene expression analysis in maize protoplasts showed that Thr420 and Ser454 of ZmCCaMK were important for BR-induced antioxidant defense.	Brassinosteroids	120-122	putative calcium/calmodulin dependent protein kinase	Zea mays	93-100
32220322-4	2020	Arabidopsis thaliana plants that lack the three receptor kinases BRASSINOSTEROID INSENSITIVE 1 (BRI1), BRI1-LIKE 1 (BRL1), and BRL3 ("bri3" mutants) can no longer sense brassinosteroid phytohormones and display severe dwarfism as well as patterning and differentiation defects, including disturbed phloem development.	Brassinosteroids	169-184	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	65-100
32220322-6	2020	Although this effect is brassinosteroid-dependent, it cannot be reproduced with dominant versions of known downstream effectors of BRI1 signaling and therefore possibly involves a non-canonical signaling output.	Brassinosteroids	24-39	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	131-135
32220322-10	2020	Our results thus reveal local and systemic effects of brassinosteroid perception in the phloem: whereas it locally antagonizes CLE45 signaling to permit phloem differentiation, it systemically instructs plant organ formation via a phloem-derived, non-cell-autonomous signal.	Brassinosteroids	54-69	CLAVATA3/ESR-RELATED 45	Arabidopsis thaliana	127-132
32508516-1	2020	Arabidopsis bHLH-type transcription factors-BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1)-play key roles in brassinosteroid (BR) signaling.	Brassinosteroids	44-59	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	92-96
32508516-1	2020	Arabidopsis bHLH-type transcription factors-BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1)-play key roles in brassinosteroid (BR) signaling.	Brassinosteroids	44-59	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	102-126
32508516-1	2020	Arabidopsis bHLH-type transcription factors-BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1)-play key roles in brassinosteroid (BR) signaling.	Brassinosteroids	152-167	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	92-96
32508516-1	2020	Arabidopsis bHLH-type transcription factors-BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1)-play key roles in brassinosteroid (BR) signaling.	Brassinosteroids	152-167	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	102-126
32508516-1	2020	Arabidopsis bHLH-type transcription factors-BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1)-play key roles in brassinosteroid (BR) signaling.	Brassinosteroids	44-46	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	92-96
32508516-1	2020	Arabidopsis bHLH-type transcription factors-BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1)-play key roles in brassinosteroid (BR) signaling.	Brassinosteroids	44-46	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	102-126
32508516-1	2020	Arabidopsis bHLH-type transcription factors-BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1)-play key roles in brassinosteroid (BR) signaling.	Brassinosteroids	44-46	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	128-132
31081597-0	2020	Photoexcited phytochrome B interacts with brassinazoleresistant 1 to repress brassinosteroid signaling in Arabidopsis.	Brassinosteroids	77-92	phytochrome B	Arabidopsis thaliana	13-26
32109396-7	2020	BR treatment stimulates ULP1a degradation, allowing SUMOylated BZR1 to accumulate and promote growth.	Brassinosteroids	0-2	UB-like protease 1A	Arabidopsis thaliana	24-29
32109396-7	2020	BR treatment stimulates ULP1a degradation, allowing SUMOylated BZR1 to accumulate and promote growth.	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	63-67
32143576-0	2020	PcDWF1, a pear brassinosteroid biosynthetic gene homologous to AtDWARF1, affected the vegetative and reproductive growth of plants.	Brassinosteroids	15-30	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	63-71
32114884-0	2020	Brassinosteroids signaling via BZR1 down-regulates expression of ACC oxidase 4 to control growth of Arabidopsis thaliana seedlings.	Brassinosteroids	0-16	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	31-35
32114884-4	2020	Exogenously-applied brassinosteroids (BRs) inhibited the expression of ACO4, and an enhanced ACO4 expression was found in det2, a BR-deficient mutant.	Brassinosteroids	20-36	ethylene-forming enzyme	Arabidopsis thaliana	71-75
32114884-4	2020	Exogenously-applied brassinosteroids (BRs) inhibited the expression of ACO4, and an enhanced ACO4 expression was found in det2, a BR-deficient mutant.	Brassinosteroids	38-41	ethylene-forming enzyme	Arabidopsis thaliana	71-75
32114884-4	2020	Exogenously-applied brassinosteroids (BRs) inhibited the expression of ACO4, and an enhanced ACO4 expression was found in det2, a BR-deficient mutant.	Brassinosteroids	38-40	ethylene-forming enzyme	Arabidopsis thaliana	71-75
32326491-5	2020	Recent studies in the model plant Arabidopsis demonstrated that BR biosynthesis and signal transduction, especially the regulatory components BIN2 and BES1/BZR1, are finely tuned by various environmental cues.	Brassinosteroids	64-66	Protein kinase superfamily protein	Arabidopsis thaliana	142-146
32326491-5	2020	Recent studies in the model plant Arabidopsis demonstrated that BR biosynthesis and signal transduction, especially the regulatory components BIN2 and BES1/BZR1, are finely tuned by various environmental cues.	Brassinosteroids	64-66	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	151-155
32326491-5	2020	Recent studies in the model plant Arabidopsis demonstrated that BR biosynthesis and signal transduction, especially the regulatory components BIN2 and BES1/BZR1, are finely tuned by various environmental cues.	Brassinosteroids	64-66	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	156-160
32050026-0	2020	Corrigendum: ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1.	Brassinosteroids	71-86	transcription termination factor 2	Homo sapiens	31-39
31783407-0	2020	ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with ICE1.	Brassinosteroids	58-73	interactor of little elongation complex ELL subunit 1	Homo sapiens	124-128
31902106-3	2020	Previously, we showed that 14-3-3 proteins directly interact with the Brassinosteroid Insensitive 1 (BRI1), the BR receptor kinase, and are also subject to phosphorylation in a BR-dependent manner.	Brassinosteroids	112-114	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	70-105
31667846-9	2020	Moreover, GhFP1 protein could directly bind to the promoters of GhDWF4 and GhCPD to activate expressions of these BR-related genes.	Brassinosteroids	114-116	cytochrome P450 90B1-like	Gossypium hirsutum	64-70
31783407-6	2020	Formation of the AIF2-ICE1 complex and subsequent upregulation of C-REPEAT BINDING FACTORs (CBFs) negatively regulates dark-triggered, BR-induced leaf senescence.	Brassinosteroids	135-137	interactor of little elongation complex ELL subunit 1	Homo sapiens	22-26
31748330-0	2020	RETRACTION: OST1 Activation by the Brassinosteroid-Regulated Kinase CDG1-LIKE1 in Stomatal Closure.	Brassinosteroids	35-50	ribophorin I	Homo sapiens	12-16
32117357-0	2020	Brassinosteroids Inhibit Autotropic Root Straightening by Modifying Filamentous-Actin Organization and Dynamics.	Brassinosteroids	0-16	actin-7	Zea mays	80-85
31907627-8	2020	JA might rapidly activate RAV1 and KAN1 to repress brassinosteroid (BR) response genes, upregulate KAN1, the C2H2 TF families ZF2, ZF3, ZAT6, and STZ/ZAT10 to repress the biosynthesis, transport, and signaling of auxin to arrest growth.	Brassinosteroids	51-66	related to ABI3/VP1 1	Arabidopsis thaliana	26-30
31907627-8	2020	JA might rapidly activate RAV1 and KAN1 to repress brassinosteroid (BR) response genes, upregulate KAN1, the C2H2 TF families ZF2, ZF3, ZAT6, and STZ/ZAT10 to repress the biosynthesis, transport, and signaling of auxin to arrest growth.	Brassinosteroids	51-66	Homeodomain-like superfamily protein	Arabidopsis thaliana	35-39
31907627-8	2020	JA might rapidly activate RAV1 and KAN1 to repress brassinosteroid (BR) response genes, upregulate KAN1, the C2H2 TF families ZF2, ZF3, ZAT6, and STZ/ZAT10 to repress the biosynthesis, transport, and signaling of auxin to arrest growth.	Brassinosteroids	68-70	related to ABI3/VP1 1	Arabidopsis thaliana	26-30
31641077-0	2020	A mutant allele uncouples the brassinosteroid-dependent and independent functions of BRASSINOSTEROID INSENSITIVE 1.	Brassinosteroids	30-45	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	85-114
31641077-8	2020	Here, we report a BRI1 mutant, bri1cnu4, which differentially affects canonical BR signaling and RLP44 function in the vasculature.	Brassinosteroids	18-20	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	31-39
31641077-8	2020	Here, we report a BRI1 mutant, bri1cnu4, which differentially affects canonical BR signaling and RLP44 function in the vasculature.	Brassinosteroids	18-20	receptor like protein 44	Arabidopsis thaliana	97-102
31641077-11	2020	Consistent with this, the mild BR response phenotype of bri1cnu4 is a recessive trait, whereas the RLP44-mediated xylem phenotype is semi-dominant.	Brassinosteroids	31-33	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	56-64
31641077-12	2020	Our results highlight the complexity of plant plasma membrane receptor function and provide a tool to dissect BR signaling-related roles of BRI1 from its non-canonical functions.	Brassinosteroids	110-112	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	140-144
32093294-3	2020	Here we observed that overexpression of BAK1 in Arabidopsis interferes with the function of high light in promoting plant growth and development, which is independent of the brassinosteroid (BR) signaling pathway.	Brassinosteroids	174-189	BRI1-associated receptor kinase	Arabidopsis thaliana	40-44
32093294-3	2020	Here we observed that overexpression of BAK1 in Arabidopsis interferes with the function of high light in promoting plant growth and development, which is independent of the brassinosteroid (BR) signaling pathway.	Brassinosteroids	191-193	BRI1-associated receptor kinase	Arabidopsis thaliana	40-44
31767691-6	2020	We observed that brassinosteroid application mimicked the auxin response, showing both early and late microtubule array effects, and induced transverse patterning in the axr2-1 mutant.	Brassinosteroids	17-32	indole-3-acetic acid 7	Arabidopsis thaliana	170-174
31639820-0	2020	CIRCADIAN CLOCK ASSOCIATED 1 and ATAF2 differentially suppress cytochrome P450-mediated brassinosteroid inactivation.	Brassinosteroids	88-103	circadian clock associated 1	Arabidopsis thaliana	0-28
31639820-0	2020	CIRCADIAN CLOCK ASSOCIATED 1 and ATAF2 differentially suppress cytochrome P450-mediated brassinosteroid inactivation.	Brassinosteroids	88-103	NAC (No Apical Meristem) domain transcriptional regulator superfamily protein	Arabidopsis thaliana	33-38
31934815-3	2020	Therefore we aimed to rescue the SlSUT2 silencing phenotype by local brassinosteroid application.	Brassinosteroids	69-84	sucrose transporter-like protein	Solanum lycopersicum	33-39
31748330-0	2020	RETRACTION: OST1 Activation by the Brassinosteroid-Regulated Kinase CDG1-LIKE1 in Stomatal Closure.	Brassinosteroids	35-50	phosphomannomutase 2	Homo sapiens	68-72
31797871-0	2019	Brassinosteroid signaling delimits root gravitropism via sorting of the Arabidopsis PIN2 auxin transporter.	Brassinosteroids	0-15	Auxin efflux carrier family protein	Arabidopsis thaliana	84-88
31983879-5	2019	We characterized the two genes, SlS5alphaR1 and SlS5alphaR2, which show high homology with DET2, a brassinosteroid 5alpha reductase of Arabidopsis thaliana.	Brassinosteroids	99-114	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	91-95
31681394-8	2019	Furthermore, the expression pattern of genes encoding enzymes that metabolize phytohormones raises the possibility that a drastic change in the homeostasis of phytohormones, such as abscisic acid, brassinosteroid, and gibberellin, may contribute to increasing stress tolerance in hda19-3 and quint plants.	Brassinosteroids	197-212	histone deacetylase 1	Arabidopsis thaliana	280-285
31563783-0	2019	Glutaredoxin S25 and its interacting TGACG motif-binding factor TGA2 mediate brassinosteroid-induced chlorothalonil metabolism in tomato plants.	Brassinosteroids	77-92	glutaredoxin	Solanum lycopersicum	0-12
31803215-3	2019	In Arabidopsis thaliana, the RLCK BOTRYTIS-INDUCED KINASE1 (BIK1) associates with multiple RLKs to regulate pathogen defense responses and brassinosteroid (BR) signaling.	Brassinosteroids	139-154	botrytis-induced kinase1	Arabidopsis thaliana	34-58
31803215-3	2019	In Arabidopsis thaliana, the RLCK BOTRYTIS-INDUCED KINASE1 (BIK1) associates with multiple RLKs to regulate pathogen defense responses and brassinosteroid (BR) signaling.	Brassinosteroids	139-154	botrytis-induced kinase1	Arabidopsis thaliana	60-64
31803215-3	2019	In Arabidopsis thaliana, the RLCK BOTRYTIS-INDUCED KINASE1 (BIK1) associates with multiple RLKs to regulate pathogen defense responses and brassinosteroid (BR) signaling.	Brassinosteroids	156-158	botrytis-induced kinase1	Arabidopsis thaliana	34-58
31803215-3	2019	In Arabidopsis thaliana, the RLCK BOTRYTIS-INDUCED KINASE1 (BIK1) associates with multiple RLKs to regulate pathogen defense responses and brassinosteroid (BR) signaling.	Brassinosteroids	156-158	botrytis-induced kinase1	Arabidopsis thaliana	60-64
31189737-8	2019	Depleting the endogenous BR content reduces plasma membrane localization of TTL3-GFP, while increasing BR content causes its plasma membrane relocalization, where it strengthens the association of BR signaling components.	Brassinosteroids	25-27	tetratricopetide-repeat thioredoxin-like 3	Arabidopsis thaliana	76-80
31290980-0	2019	Sumoylation of BRI1-EMS-SUPPRESSOR 1 (BES1) by the SUMO E3 Ligase SIZ1 Negatively Regulates Brassinosteroids Signaling in Arabidopsis thaliana.	Brassinosteroids	92-108	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	15-36
31290980-0	2019	Sumoylation of BRI1-EMS-SUPPRESSOR 1 (BES1) by the SUMO E3 Ligase SIZ1 Negatively Regulates Brassinosteroids Signaling in Arabidopsis thaliana.	Brassinosteroids	92-108	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	38-42
31290980-0	2019	Sumoylation of BRI1-EMS-SUPPRESSOR 1 (BES1) by the SUMO E3 Ligase SIZ1 Negatively Regulates Brassinosteroids Signaling in Arabidopsis thaliana.	Brassinosteroids	92-108	DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain-containing protein	Arabidopsis thaliana	66-70
31290980-4	2019	T-DNA insertion mutant siz1-2 shows BL (Brassinolide, the most active BR) hypersensitivity and BRZ (Brassinazole, a BR biosynthesis inhibitor) insensitivity during hypocotyl elongation.	Brassinosteroids	70-72	DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain-containing protein	Arabidopsis thaliana	23-29
31519953-1	2019	BES1 and BZR1 were originally identified as two key transcription factors specifically regulating brassinosteroid (BR)-mediated gene expression.	Brassinosteroids	98-113	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	0-4
31519953-1	2019	BES1 and BZR1 were originally identified as two key transcription factors specifically regulating brassinosteroid (BR)-mediated gene expression.	Brassinosteroids	98-113	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	9-13
31519953-1	2019	BES1 and BZR1 were originally identified as two key transcription factors specifically regulating brassinosteroid (BR)-mediated gene expression.	Brassinosteroids	115-117	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	0-4
31519953-1	2019	BES1 and BZR1 were originally identified as two key transcription factors specifically regulating brassinosteroid (BR)-mediated gene expression.	Brassinosteroids	115-117	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	9-13
31381816-4	2019	Transactivation analysis of luciferase reporter gene was performed for ERalpha and AP-1 factors after the brassinosteroid treatment.	Brassinosteroids	106-121	estrogen receptor 1	Homo sapiens	71-78
31381816-4	2019	Transactivation analysis of luciferase reporter gene was performed for ERalpha and AP-1 factors after the brassinosteroid treatment.	Brassinosteroids	106-121	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	83-87
31009078-1	2019	BRI1-EMS-SUPPRESSOR 1 (BES1) functions as a key regulator in the brassinosteroid (BR) pathway that promotes plant growth.	Brassinosteroids	65-80	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	0-21
31009078-1	2019	BRI1-EMS-SUPPRESSOR 1 (BES1) functions as a key regulator in the brassinosteroid (BR) pathway that promotes plant growth.	Brassinosteroids	65-80	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	23-27
31009078-1	2019	BRI1-EMS-SUPPRESSOR 1 (BES1) functions as a key regulator in the brassinosteroid (BR) pathway that promotes plant growth.	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	23-27
31189737-6	2019	TTL3 directly interacts with a constitutively active BRASSINOSTEROID INSENSITIVE1 (BRI1) receptor kinase, BRI1-SUPPRESSOR1 phosphatase, and the BRASSINAZOLE RESISTANT1 transcription factor and associates with BR-SIGNALING KINASE1, BRASSINOSTEROID INSENSITIVE2 kinases, but not with BRI1-ASSOCIATED KINASE1.	Brassinosteroids	53-68	tetratricopetide-repeat thioredoxin-like 3	Arabidopsis thaliana	0-4
31189737-6	2019	TTL3 directly interacts with a constitutively active BRASSINOSTEROID INSENSITIVE1 (BRI1) receptor kinase, BRI1-SUPPRESSOR1 phosphatase, and the BRASSINAZOLE RESISTANT1 transcription factor and associates with BR-SIGNALING KINASE1, BRASSINOSTEROID INSENSITIVE2 kinases, but not with BRI1-ASSOCIATED KINASE1.	Brassinosteroids	53-68	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	83-87
31280329-0	2019	Transcriptional network regulation of the brassinosteroid signaling pathway by the BES1-TPL-HDA19 co-repressor complex.	Brassinosteroids	42-57	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	83-87
31280329-0	2019	Transcriptional network regulation of the brassinosteroid signaling pathway by the BES1-TPL-HDA19 co-repressor complex.	Brassinosteroids	42-57	Transducin family protein / WD-40 repeat family protein	Arabidopsis thaliana	88-91
31280329-0	2019	Transcriptional network regulation of the brassinosteroid signaling pathway by the BES1-TPL-HDA19 co-repressor complex.	Brassinosteroids	42-57	histone deacetylase 1	Arabidopsis thaliana	92-97
31126980-1	2019	APETALA2/ETHYLENE RESPONSIVE FACTOR (AP2/ERF) family transcription factors have well-documented functions in stress responses, but their roles in brassinosteroid (BR)-regulated growth and stress responses have not been established.	Brassinosteroids	146-161	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	37-40
31126980-1	2019	APETALA2/ETHYLENE RESPONSIVE FACTOR (AP2/ERF) family transcription factors have well-documented functions in stress responses, but their roles in brassinosteroid (BR)-regulated growth and stress responses have not been established.	Brassinosteroids	163-165	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	37-40
31344072-2	2019	Enzymes DET2 and CYP90 family are responsible for BR biosynthesis in seed plants.	Brassinosteroids	50-52	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	8-12
31344072-2	2019	Enzymes DET2 and CYP90 family are responsible for BR biosynthesis in seed plants.	Brassinosteroids	50-52	Cytochrome P450 superfamily protein	Arabidopsis thaliana	17-22
31196007-3	2019	Phosphorylated BRASSINOSTEROID INSENSITIVE1 (BRI1), the rate-limiting receptor in BR signalling, transduces BR signals, and we recently demonstrated that modifying BRI1 phosphorylation sites alters BR signal strength and botanical characteristics in Arabidopsis.	Brassinosteroids	15-30	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	45-49
31196007-3	2019	Phosphorylated BRASSINOSTEROID INSENSITIVE1 (BRI1), the rate-limiting receptor in BR signalling, transduces BR signals, and we recently demonstrated that modifying BRI1 phosphorylation sites alters BR signal strength and botanical characteristics in Arabidopsis.	Brassinosteroids	15-30	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	164-168
30908972-0	2019	ABSCISIC ACID-INSENSITIVE 3 is involved in brassinosteroid-mediated regulation of flowering in plants.	Brassinosteroids	43-58	AP2/B3-like transcriptional factor family protein	Arabidopsis thaliana	0-27
31182839-6	2019	We also determined the crystal structures of CYP90B1 complexed with uniconazole6,7 or brassinazole8, which inhibit BR biosynthesis.	Brassinosteroids	115-117	Cytochrome P450 superfamily protein	Arabidopsis thaliana	45-52
30908972-2	2019	A recent study showed that epigenetic repression of ABI3 by brassinosteroid (BR)-activated BRI1 EMS SUPPRESSOR1 (BES1)-TOPLESS (TPL)HISTONE DEACETYLASE 19 (HDA19) repressor complex is a critical event for promoting seed germination and early seedling development.	Brassinosteroids	60-75	AP2/B3-like transcriptional factor family protein	Arabidopsis thaliana	52-56
30908972-2	2019	A recent study showed that epigenetic repression of ABI3 by brassinosteroid (BR)-activated BRI1 EMS SUPPRESSOR1 (BES1)-TOPLESS (TPL)HISTONE DEACETYLASE 19 (HDA19) repressor complex is a critical event for promoting seed germination and early seedling development.	Brassinosteroids	60-75	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	91-111
31128699-8	2019	These results indicated that PeGSK1 is functionally similar to AtGSK1 and inhibited cell growth via the brassinosteroid signaling pathway.	Brassinosteroids	104-119	GSK3/SHAGGY-like protein kinase 1	Arabidopsis thaliana	63-69
30908972-2	2019	A recent study showed that epigenetic repression of ABI3 by brassinosteroid (BR)-activated BRI1 EMS SUPPRESSOR1 (BES1)-TOPLESS (TPL)HISTONE DEACETYLASE 19 (HDA19) repressor complex is a critical event for promoting seed germination and early seedling development.	Brassinosteroids	60-75	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	113-117
30908972-2	2019	A recent study showed that epigenetic repression of ABI3 by brassinosteroid (BR)-activated BRI1 EMS SUPPRESSOR1 (BES1)-TOPLESS (TPL)HISTONE DEACETYLASE 19 (HDA19) repressor complex is a critical event for promoting seed germination and early seedling development.	Brassinosteroids	60-75	histone deacetylase 1	Arabidopsis thaliana	156-161
30908972-2	2019	A recent study showed that epigenetic repression of ABI3 by brassinosteroid (BR)-activated BRI1 EMS SUPPRESSOR1 (BES1)-TOPLESS (TPL)HISTONE DEACETYLASE 19 (HDA19) repressor complex is a critical event for promoting seed germination and early seedling development.	Brassinosteroids	77-79	AP2/B3-like transcriptional factor family protein	Arabidopsis thaliana	52-56
30908972-2	2019	A recent study showed that epigenetic repression of ABI3 by brassinosteroid (BR)-activated BRI1 EMS SUPPRESSOR1 (BES1)-TOPLESS (TPL)HISTONE DEACETYLASE 19 (HDA19) repressor complex is a critical event for promoting seed germination and early seedling development.	Brassinosteroids	77-79	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	91-111
30908972-2	2019	A recent study showed that epigenetic repression of ABI3 by brassinosteroid (BR)-activated BRI1 EMS SUPPRESSOR1 (BES1)-TOPLESS (TPL)HISTONE DEACETYLASE 19 (HDA19) repressor complex is a critical event for promoting seed germination and early seedling development.	Brassinosteroids	77-79	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	113-117
30908972-2	2019	A recent study showed that epigenetic repression of ABI3 by brassinosteroid (BR)-activated BRI1 EMS SUPPRESSOR1 (BES1)-TOPLESS (TPL)HISTONE DEACETYLASE 19 (HDA19) repressor complex is a critical event for promoting seed germination and early seedling development.	Brassinosteroids	77-79	histone deacetylase 1	Arabidopsis thaliana	156-161
31083521-9	2019	Furthermore, BR-induced dephosphorylation of transcription factor BZR1 was decreased in big3-1 big5-1 double mutants.	Brassinosteroids	13-15	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	66-70
31164898-1	2019	Brassinosteroid insensitive 1 (BRI1) is a multidomain plant leucine-rich repeat receptor-like kinase (LRR-RLK), belongs to the LRR X subfamily.	Brassinosteroids	0-15	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	31-35
31164898-2	2019	BRI1 perceives plant hormone brassinosteroids (BRs) through its extracellular domain that constitutes of LRRs interrupted by a 70 amino acid residue island domain (ID), which activates the kinase domain (KD) in its intracellular domain to trigger BR response.	Brassinosteroids	29-45	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	0-4
31164898-11	2019	Furthermore, bri1-235 protein was localized in endoplasmic reticulum rather than plasma membrane, suggestive of a cause for reducing BR sensitive in bri1-235.	Brassinosteroids	133-135	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	13-17
31164898-11	2019	Furthermore, bri1-235 protein was localized in endoplasmic reticulum rather than plasma membrane, suggestive of a cause for reducing BR sensitive in bri1-235.	Brassinosteroids	133-135	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	149-153
30763615-0	2019	The Blue-Light Receptor CRY1 Interacts with BZR1 and BIN2 to Modulate the Phosphorylation and Nuclear Function of BZR1 in Repressing BR Signaling in Arabidopsis.	Brassinosteroids	133-135	cryptochrome 1	Arabidopsis thaliana	24-28
30763615-0	2019	The Blue-Light Receptor CRY1 Interacts with BZR1 and BIN2 to Modulate the Phosphorylation and Nuclear Function of BZR1 in Repressing BR Signaling in Arabidopsis.	Brassinosteroids	133-135	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	44-48
30763615-0	2019	The Blue-Light Receptor CRY1 Interacts with BZR1 and BIN2 to Modulate the Phosphorylation and Nuclear Function of BZR1 in Repressing BR Signaling in Arabidopsis.	Brassinosteroids	133-135	Protein kinase superfamily protein	Arabidopsis thaliana	53-57
30763615-0	2019	The Blue-Light Receptor CRY1 Interacts with BZR1 and BIN2 to Modulate the Phosphorylation and Nuclear Function of BZR1 in Repressing BR Signaling in Arabidopsis.	Brassinosteroids	133-135	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	114-118
30763615-3	2019	We report here that CRY1 inhibits hypocotyl elongation by repressing brassinosteroid (BR) signaling.	Brassinosteroids	69-84	cryptochrome 1	Arabidopsis thaliana	20-24
30673841-7	2019	The gradual retardation of xylem development phenotypes during shoot vegetative growth in the BR-deficient MT tomato mutant recovered completely in response to exogenous BR treatment or genetic complementation of the BR biosynthetic DWARF (D) gene.	Brassinosteroids	94-96	6-deoxocastasterone oxidase	Solanum lycopersicum	233-238
30821966-5	2019	Under optimized conditions, the limits of detection were 1.38-6.75 pg mL-1 for five brassinosteroids in the oilseed rape samples.	Brassinosteroids	84-100	L1 cell adhesion molecule	Mus musculus	70-74
30844693-11	2019	Therefore, our results reveal that BR contents positively regulated tomato drought resistance and that BR signaling intensity via BRI1 was negatively related to the drought resistance.	Brassinosteroids	103-105	brassinosteroid LRR receptor kinase	Solanum lycopersicum	130-134
31057577-13	2019	Consistently, bpc6, bpc4 bpc6, and lhp1 bpc4 bpc4 mutants display brassinosteroid-dependent root growth phenotypes.	Brassinosteroids	66-81	basic pentacysteine 6	Arabidopsis thaliana	14-18
31057577-13	2019	Consistently, bpc6, bpc4 bpc6, and lhp1 bpc4 bpc4 mutants display brassinosteroid-dependent root growth phenotypes.	Brassinosteroids	66-81	basic pentacysteine 6	Arabidopsis thaliana	25-29
30873200-7	2019	While some AP2/ERFs are implicated in growth and developmental processes mediated by gibberellins (GAs), cytokinins (CTK), and brassinosteroids (BRs).	Brassinosteroids	127-143	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	11-14
30388258-0	2019	phyB Interacts with BES1 to Regulate Brassinosteroid Signaling in Arabidopsis.	Brassinosteroids	37-52	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	20-24
30388258-10	2019	Taken together, we suggest that the interaction of phyB with dephosphorylated BES1 may allow plants to balance light and BR signaling by repressing transcriptional activity of BES1 to regulate expression of its target genes.	Brassinosteroids	121-123	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	78-82
30388258-10	2019	Taken together, we suggest that the interaction of phyB with dephosphorylated BES1 may allow plants to balance light and BR signaling by repressing transcriptional activity of BES1 to regulate expression of its target genes.	Brassinosteroids	121-123	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	176-180
30333151-1	2018	BRASSINOSTEROID-INSENSITIVE1 (BRI1) is a leucine-rich-repeat receptor-like kinase that functions as the cell surface receptor for brassinosteroids (BRs).	Brassinosteroids	130-146	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	0-28
30523782-2	2018	We previously demonstrated that Tomato leaf curl Yunnan virus (TLCYnV) C4 induces plant developmental abnormalities at least partically by decreasing the accumulation of NbSKeta, an ortholog of Arabidopsis BIN2 kinase involved in the brassinosteroid signaling pathway, in the nucleus through directing it to the plasma membrane.	Brassinosteroids	234-249	Protein kinase superfamily protein	Arabidopsis thaliana	206-210
30389669-5	2018	BES1 homodimers bind to conserved BRRE- and G-box elements in the BR biosynthetic promoters and inhibit their expression during the day, while elevated PIF4 competes for BES1 homodimer formation, resulting in de-repressed BR biosynthesis at dawn and in response to warmth.	Brassinosteroids	34-36	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	0-4
30389669-6	2018	Our findings demonstrate a central role of PIF4 in BR synthesis activation, increased BR levels being essential to thermomorphogenic hypocotyl growth.	Brassinosteroids	51-53	phytochrome interacting factor 4	Arabidopsis thaliana	43-47
30333151-1	2018	BRASSINOSTEROID-INSENSITIVE1 (BRI1) is a leucine-rich-repeat receptor-like kinase that functions as the cell surface receptor for brassinosteroids (BRs).	Brassinosteroids	130-146	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	30-34
30333151-4	2018	Here, we show that the Arabidopsis (Arabidopsis thaliana) bri1-301 mutant receptor exhibits weak BR-triggered phosphorylation in vivo and absolutely requires its kinase activity for the limited growth that occurs in the bri1-301 mutant.	Brassinosteroids	97-99	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	58-62
30333151-4	2018	Here, we show that the Arabidopsis (Arabidopsis thaliana) bri1-301 mutant receptor exhibits weak BR-triggered phosphorylation in vivo and absolutely requires its kinase activity for the limited growth that occurs in the bri1-301 mutant.	Brassinosteroids	97-99	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	220-224
29932218-6	2018	EMR RNAi in the bri1-5 background led to partial recovery of the brassinosteroid (BR)-insensitive phenotypes as compared with the original mutant plants and increased ER stress tolerance.	Brassinosteroids	65-80	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	16-22
30459799-1	2018	Brassinosteroids (BRs) are essential phytohormones mainly perceived by a single-pass transmembrane receptor-like protein kinase (RLK), BRASSINOSTEROID INSENSITIVE 1 (BRI1).	Brassinosteroids	0-16	cysteine-rich RLK (RECEPTOR-like protein kinase) 6	Arabidopsis thaliana	99-127
30459799-1	2018	Brassinosteroids (BRs) are essential phytohormones mainly perceived by a single-pass transmembrane receptor-like protein kinase (RLK), BRASSINOSTEROID INSENSITIVE 1 (BRI1).	Brassinosteroids	0-16	cysteine-rich RLK (RECEPTOR-like protein kinase) 6	Arabidopsis thaliana	129-132
30459799-1	2018	Brassinosteroids (BRs) are essential phytohormones mainly perceived by a single-pass transmembrane receptor-like protein kinase (RLK), BRASSINOSTEROID INSENSITIVE 1 (BRI1).	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	166-170
30459799-1	2018	Brassinosteroids (BRs) are essential phytohormones mainly perceived by a single-pass transmembrane receptor-like protein kinase (RLK), BRASSINOSTEROID INSENSITIVE 1 (BRI1).	Brassinosteroids	18-21	cysteine-rich RLK (RECEPTOR-like protein kinase) 6	Arabidopsis thaliana	99-127
30459799-1	2018	Brassinosteroids (BRs) are essential phytohormones mainly perceived by a single-pass transmembrane receptor-like protein kinase (RLK), BRASSINOSTEROID INSENSITIVE 1 (BRI1).	Brassinosteroids	18-21	cysteine-rich RLK (RECEPTOR-like protein kinase) 6	Arabidopsis thaliana	129-132
30459799-1	2018	Brassinosteroids (BRs) are essential phytohormones mainly perceived by a single-pass transmembrane receptor-like protein kinase (RLK), BRASSINOSTEROID INSENSITIVE 1 (BRI1).	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	166-170
30459799-1	2018	Brassinosteroids (BRs) are essential phytohormones mainly perceived by a single-pass transmembrane receptor-like protein kinase (RLK), BRASSINOSTEROID INSENSITIVE 1 (BRI1).	Brassinosteroids	135-150	cysteine-rich RLK (RECEPTOR-like protein kinase) 6	Arabidopsis thaliana	129-132
30459799-1	2018	Brassinosteroids (BRs) are essential phytohormones mainly perceived by a single-pass transmembrane receptor-like protein kinase (RLK), BRASSINOSTEROID INSENSITIVE 1 (BRI1).	Brassinosteroids	135-150	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	166-170
30377268-3	2018	Here, we show that the hormone receptor BRASSINOSTEROID INSENSITIVE 1 (BRI1) is required for root vascular cell-fate maintenance, as BRI1 mutants show ectopic xylem in procambial position.	Brassinosteroids	40-55	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	71-75
30377268-3	2018	Here, we show that the hormone receptor BRASSINOSTEROID INSENSITIVE 1 (BRI1) is required for root vascular cell-fate maintenance, as BRI1 mutants show ectopic xylem in procambial position.	Brassinosteroids	40-55	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	133-137
30374363-8	2018	Moreover, DELTA1-PYRROLINE-5-CARBOXYLATE SYNTHASE 1 (P5CS1), TRYPTOPHAN BIOSYNTHESIS 2 (TRP2) or GALACTINOL SYNTHASE 2 (GOLS2), was also specifically regulated by EsNAC1 to retard the vegetative growth of HE lines, but not the brassinosteroid singling pathway in RD26OX lines.	Brassinosteroids	227-242	delta1-pyrroline-5-carboxylate synthase 1	Arabidopsis thaliana	10-51
29932218-6	2018	EMR RNAi in the bri1-5 background led to partial recovery of the brassinosteroid (BR)-insensitive phenotypes as compared with the original mutant plants and increased ER stress tolerance.	Brassinosteroids	82-84	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	16-22
30131420-0	2018	Photoexcited CRYPTOCHROME1 Interacts with Dephosphorylated BES1 to Regulate Brassinosteroid Signaling and Photomorphogenesis in Arabidopsis.	Brassinosteroids	76-91	cryptochrome 1	Arabidopsis thaliana	13-26
29969683-0	2018	Brassinosteroid Signaling Recruits Histone 3 Lysine-27 Demethylation Activity to FLOWERING LOCUS C Chromatin to Inhibit the Floral Transition in Arabidopsis.	Brassinosteroids	0-15	K-box region and MADS-box transcription factor family protein	Arabidopsis thaliana	81-98
29747107-0	2018	Glutaredoxin GRXS16 mediates brassinosteroid-induced apoplastic H2O2 production to promote pesticide metabolism in tomato.	Brassinosteroids	29-44	glutaredoxin	Solanum lycopersicum	0-12
30146155-5	2018	In turn, CLASP, which tethers sorting nexin 1 vesicles to microtubules, sustains brassinosteroid signaling by fostering retrieval of endocytosed BRI1 receptors to the plasma membrane.	Brassinosteroids	81-96	sorting nexin 1	Arabidopsis thaliana	30-45
30146155-5	2018	In turn, CLASP, which tethers sorting nexin 1 vesicles to microtubules, sustains brassinosteroid signaling by fostering retrieval of endocytosed BRI1 receptors to the plasma membrane.	Brassinosteroids	81-96	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	145-149
30131420-0	2018	Photoexcited CRYPTOCHROME1 Interacts with Dephosphorylated BES1 to Regulate Brassinosteroid Signaling and Photomorphogenesis in Arabidopsis.	Brassinosteroids	76-91	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	59-63
30131420-3	2018	Brassinosteroid (BR) is a key phytohormone involved in the repression of photomorphogenesis, and here, we show that the signaling mechanism of Arabidopsis CRY1 involves the inhibition of BR signaling.	Brassinosteroids	0-15	cryptochrome 1	Arabidopsis thaliana	155-159
30131420-3	2018	Brassinosteroid (BR) is a key phytohormone involved in the repression of photomorphogenesis, and here, we show that the signaling mechanism of Arabidopsis CRY1 involves the inhibition of BR signaling.	Brassinosteroids	17-19	cryptochrome 1	Arabidopsis thaliana	155-159
30131420-6	2018	In addition, CRY1 and CRY2 interact specifically with dephosphorylated BES1, the physiologically active form of BES1 that is activated by BR in a blue light-dependent manner.	Brassinosteroids	138-140	cryptochrome 1	Arabidopsis thaliana	13-17
30131420-6	2018	In addition, CRY1 and CRY2 interact specifically with dephosphorylated BES1, the physiologically active form of BES1 that is activated by BR in a blue light-dependent manner.	Brassinosteroids	138-140	cryptochrome 2	Arabidopsis thaliana	22-26
30131420-6	2018	In addition, CRY1 and CRY2 interact specifically with dephosphorylated BES1, the physiologically active form of BES1 that is activated by BR in a blue light-dependent manner.	Brassinosteroids	138-140	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	71-75
30131420-6	2018	In addition, CRY1 and CRY2 interact specifically with dephosphorylated BES1, the physiologically active form of BES1 that is activated by BR in a blue light-dependent manner.	Brassinosteroids	138-140	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	112-116
30131420-8	2018	Our study suggests that the blue light-dependent, BR-induced interaction of CRY1 with BES1 is a tightly regulated mechanism by which plants optimize photomorphogenesis according to the availability of external light and internal BR signals.	Brassinosteroids	50-52	cryptochrome 1	Arabidopsis thaliana	76-80
30131420-8	2018	Our study suggests that the blue light-dependent, BR-induced interaction of CRY1 with BES1 is a tightly regulated mechanism by which plants optimize photomorphogenesis according to the availability of external light and internal BR signals.	Brassinosteroids	50-52	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	86-90
30131420-8	2018	Our study suggests that the blue light-dependent, BR-induced interaction of CRY1 with BES1 is a tightly regulated mechanism by which plants optimize photomorphogenesis according to the availability of external light and internal BR signals.	Brassinosteroids	229-231	cryptochrome 1	Arabidopsis thaliana	76-80
30131420-8	2018	Our study suggests that the blue light-dependent, BR-induced interaction of CRY1 with BES1 is a tightly regulated mechanism by which plants optimize photomorphogenesis according to the availability of external light and internal BR signals.	Brassinosteroids	229-231	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	86-90
29897568-4	2018	In this study, we found that hypocotyl cell elongation is regulated by a network involving ethylene, auxin, and BR signalling, which is mediated by interactions among ERF72, ARF6, and BZR1.	Brassinosteroids	112-114	ethylene-responsive element binding protein	Arabidopsis thaliana	167-172
30065046-4	2018	Here, we show that BR and ABA synergistically regulate stomatal closure through crosstalk between the BR-activated kinase CDG1-LIKE1 (CDL1) and the OPEN STOMATA1 (OST1) of the ABA signaling pathway in Arabidopsis thaliana We demonstrate that the cdl1 mutant displayed reduced sensitivity to ABA in a stomatal closure assay, similar to the ost1 mutant.	Brassinosteroids	19-21	Protein kinase superfamily protein	Arabidopsis thaliana	122-132
30065046-4	2018	Here, we show that BR and ABA synergistically regulate stomatal closure through crosstalk between the BR-activated kinase CDG1-LIKE1 (CDL1) and the OPEN STOMATA1 (OST1) of the ABA signaling pathway in Arabidopsis thaliana We demonstrate that the cdl1 mutant displayed reduced sensitivity to ABA in a stomatal closure assay, similar to the ost1 mutant.	Brassinosteroids	19-21	Protein kinase superfamily protein	Arabidopsis thaliana	134-138
30065046-4	2018	Here, we show that BR and ABA synergistically regulate stomatal closure through crosstalk between the BR-activated kinase CDG1-LIKE1 (CDL1) and the OPEN STOMATA1 (OST1) of the ABA signaling pathway in Arabidopsis thaliana We demonstrate that the cdl1 mutant displayed reduced sensitivity to ABA in a stomatal closure assay, similar to the ost1 mutant.	Brassinosteroids	19-21	Protein kinase superfamily protein	Arabidopsis thaliana	148-161
30065046-4	2018	Here, we show that BR and ABA synergistically regulate stomatal closure through crosstalk between the BR-activated kinase CDG1-LIKE1 (CDL1) and the OPEN STOMATA1 (OST1) of the ABA signaling pathway in Arabidopsis thaliana We demonstrate that the cdl1 mutant displayed reduced sensitivity to ABA in a stomatal closure assay, similar to the ost1 mutant.	Brassinosteroids	19-21	Protein kinase superfamily protein	Arabidopsis thaliana	163-167
30065046-4	2018	Here, we show that BR and ABA synergistically regulate stomatal closure through crosstalk between the BR-activated kinase CDG1-LIKE1 (CDL1) and the OPEN STOMATA1 (OST1) of the ABA signaling pathway in Arabidopsis thaliana We demonstrate that the cdl1 mutant displayed reduced sensitivity to ABA in a stomatal closure assay, similar to the ost1 mutant.	Brassinosteroids	19-21	Protein kinase superfamily protein	Arabidopsis thaliana	246-250
30065046-4	2018	Here, we show that BR and ABA synergistically regulate stomatal closure through crosstalk between the BR-activated kinase CDG1-LIKE1 (CDL1) and the OPEN STOMATA1 (OST1) of the ABA signaling pathway in Arabidopsis thaliana We demonstrate that the cdl1 mutant displayed reduced sensitivity to ABA in a stomatal closure assay, similar to the ost1 mutant.	Brassinosteroids	19-21	Protein kinase superfamily protein	Arabidopsis thaliana	339-343
30065046-7	2018	BR increased phosphorylation of OST1, and the BR-induced OST1 activation was abolished in cdl1 mutants.	Brassinosteroids	0-2	Protein kinase superfamily protein	Arabidopsis thaliana	32-36
30065046-7	2018	BR increased phosphorylation of OST1, and the BR-induced OST1 activation was abolished in cdl1 mutants.	Brassinosteroids	46-48	Protein kinase superfamily protein	Arabidopsis thaliana	57-61
30065046-7	2018	BR increased phosphorylation of OST1, and the BR-induced OST1 activation was abolished in cdl1 mutants.	Brassinosteroids	46-48	Protein kinase superfamily protein	Arabidopsis thaliana	90-94
30099381-0	2018	CDL1-OST1 Interaction as a Focal Point of Brassinosteroid-Abscisic Acid Hormone Signaling Crosstalk.	Brassinosteroids	42-57	ribophorin I	Homo sapiens	5-9
29860272-5	2018	Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner.	Brassinosteroids	132-147	cryptochrome 1	Arabidopsis thaliana	31-35
29860272-5	2018	Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner.	Brassinosteroids	132-147	cryptochrome-interacting basic-helix-loop-helix 1	Arabidopsis thaliana	84-88
29860272-5	2018	Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner.	Brassinosteroids	132-147	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	90-94
29897568-4	2018	In this study, we found that hypocotyl cell elongation is regulated by a network involving ethylene, auxin, and BR signalling, which is mediated by interactions among ERF72, ARF6, and BZR1.	Brassinosteroids	112-114	auxin response factor 6	Arabidopsis thaliana	174-178
29897568-4	2018	In this study, we found that hypocotyl cell elongation is regulated by a network involving ethylene, auxin, and BR signalling, which is mediated by interactions among ERF72, ARF6, and BZR1.	Brassinosteroids	112-114	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	184-188
29275167-0	2018	Abscisic Acid Signaling Inhibits Brassinosteroid Signaling through Dampening the Dephosphorylation of BIN2 by ABI1 and ABI2.	Brassinosteroids	33-48	bridging integrator 2	Homo sapiens	102-106
29860272-5	2018	Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner.	Brassinosteroids	149-151	cryptochrome 1	Arabidopsis thaliana	31-35
29860272-5	2018	Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner.	Brassinosteroids	149-151	cryptochrome-interacting basic-helix-loop-helix 1	Arabidopsis thaliana	84-88
29860272-5	2018	Moreover, we demonstrated that CRY1 physically interacted with the close homolog of CIB1, HBI1, which is known to act downstream of brassinosteroid (BR) and gibberellin acid (GA) signaling pathways to promote hypocotyl elongation, in a blue light-dependent manner.	Brassinosteroids	149-151	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	90-94
29215737-5	2018	Further evidence showed that NIA1 pathway was responsible for BR-induced NO accumulation in Arabidopsis.	Brassinosteroids	62-64	nitrate reductase 1	Arabidopsis thaliana	29-33
28776692-0	2018	Brassinosteroid-mediated apoplastic H2 O2 -glutaredoxin 12/14 cascade regulates antioxidant capacity in response to chilling in tomato.	Brassinosteroids	0-15	glutaredoxin	Solanum lycopersicum	43-55
28776692-7	2018	BR increased transcripts of RESPIRATORY BURST OXIDASE HOMOLOG1 (RBOH1) and GLUTAREDOXIN (GRX) genes, and BR-induced chilling tolerance was associated with an increase in the ratio of reduced/oxidized 2-cysteine peroxiredoxin (2-Cys Prx) and activation of antioxidant enzymes.	Brassinosteroids	0-2	NADPH oxidase	Solanum lycopersicum	28-62
28776692-7	2018	BR increased transcripts of RESPIRATORY BURST OXIDASE HOMOLOG1 (RBOH1) and GLUTAREDOXIN (GRX) genes, and BR-induced chilling tolerance was associated with an increase in the ratio of reduced/oxidized 2-cysteine peroxiredoxin (2-Cys Prx) and activation of antioxidant enzymes.	Brassinosteroids	0-2	NADPH oxidase	Solanum lycopersicum	64-69
28776692-7	2018	BR increased transcripts of RESPIRATORY BURST OXIDASE HOMOLOG1 (RBOH1) and GLUTAREDOXIN (GRX) genes, and BR-induced chilling tolerance was associated with an increase in the ratio of reduced/oxidized 2-cysteine peroxiredoxin (2-Cys Prx) and activation of antioxidant enzymes.	Brassinosteroids	0-2	glutaredoxin	Solanum lycopersicum	75-87
28776692-7	2018	BR increased transcripts of RESPIRATORY BURST OXIDASE HOMOLOG1 (RBOH1) and GLUTAREDOXIN (GRX) genes, and BR-induced chilling tolerance was associated with an increase in the ratio of reduced/oxidized 2-cysteine peroxiredoxin (2-Cys Prx) and activation of antioxidant enzymes.	Brassinosteroids	0-2	glutaredoxin	Solanum lycopersicum	89-92
28776692-10	2018	Our study suggests that BR enhances chilling tolerance through a signalling cascade involving RBOH1, GRXs, and 2-Cys Prx in tomato.	Brassinosteroids	24-26	NADPH oxidase	Solanum lycopersicum	94-99
29432595-2	2018	A loss-of-function mutant, dwf1, showed similar phenotypic abnormalities to brassinosteroid (BR)-deficient mutants.	Brassinosteroids	76-91	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	27-31
29432595-2	2018	A loss-of-function mutant, dwf1, showed similar phenotypic abnormalities to brassinosteroid (BR)-deficient mutants.	Brassinosteroids	93-95	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	27-31
28370079-5	2018	Silencing of RBOH1, WFI1, MPK1, MPK2 and MPK3 all increased the root susceptibility to nematode and attenuated BR-induced resistance against the nematode.	Brassinosteroids	111-113	NADPH oxidase	Solanum lycopersicum	13-18
28370079-5	2018	Silencing of RBOH1, WFI1, MPK1, MPK2 and MPK3 all increased the root susceptibility to nematode and attenuated BR-induced resistance against the nematode.	Brassinosteroids	111-113	whitefly-induced gp91-phox	Solanum lycopersicum	20-24
28370079-5	2018	Silencing of RBOH1, WFI1, MPK1, MPK2 and MPK3 all increased the root susceptibility to nematode and attenuated BR-induced resistance against the nematode.	Brassinosteroids	111-113	Mitogen-activated protein kinase	Solanum lycopersicum	26-30
28370079-5	2018	Silencing of RBOH1, WFI1, MPK1, MPK2 and MPK3 all increased the root susceptibility to nematode and attenuated BR-induced resistance against the nematode.	Brassinosteroids	111-113	mitogen-activated protein kinase 2	Solanum lycopersicum	32-36
28370079-5	2018	Silencing of RBOH1, WFI1, MPK1, MPK2 and MPK3 all increased the root susceptibility to nematode and attenuated BR-induced resistance against the nematode.	Brassinosteroids	111-113	mitogen-activated protein kinase 3	Solanum lycopersicum	41-45
29462426-0	2018	Arabidopsis BRASSINOSTEROID INACTIVATOR2 is a typical BAHD acyltransferase involved in brassinosteroid homeostasis.	Brassinosteroids	87-102	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	12-27
28881416-8	2018	In tomato HMGS-OE seedlings, genes associated with the biosyntheses of C10, C15 and C20 universal precursors of isoprenoids, phytosterols, brassinosteroids, dolichols, methylerythritol phosphate, carotenoid and vitamin E were up-regulated.	Brassinosteroids	139-155	3-hydroxy-3-methylglutaryl coenzyme A synthase	Solanum lycopersicum	10-14
29329424-0	2018	Brassinosteroids regulate pavement cell growth by mediating BIN2-induced microtubule stabilization.	Brassinosteroids	0-16	Protein kinase superfamily protein	Arabidopsis thaliana	60-64
29432171-4	2018	BR perception promotes BRI1 ubiquitination and association with PUB12 and PUB13 through phosphorylation at serine 344 residue.	Brassinosteroids	0-2	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	23-27
29432171-4	2018	BR perception promotes BRI1 ubiquitination and association with PUB12 and PUB13 through phosphorylation at serine 344 residue.	Brassinosteroids	0-2	armadillo/beta-catenin repeat protein	Arabidopsis thaliana	64-69
29432171-4	2018	BR perception promotes BRI1 ubiquitination and association with PUB12 and PUB13 through phosphorylation at serine 344 residue.	Brassinosteroids	0-2	plant U-box 13	Arabidopsis thaliana	74-79
29275167-0	2018	Abscisic Acid Signaling Inhibits Brassinosteroid Signaling through Dampening the Dephosphorylation of BIN2 by ABI1 and ABI2.	Brassinosteroids	33-48	abl interactor 1	Homo sapiens	110-114
29275167-0	2018	Abscisic Acid Signaling Inhibits Brassinosteroid Signaling through Dampening the Dephosphorylation of BIN2 by ABI1 and ABI2.	Brassinosteroids	33-48	abl interactor 2	Homo sapiens	119-123
29324765-2	2018	Here, a det2-9 mutant defective in BR synthesis was identified from an EMS mutant screening for defects in root length, and was used to investigate the role of BR in root development in Arabidopsis.	Brassinosteroids	35-37	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	8-14
29337075-0	2018	Brassinosteroids Dominate Hormonal Regulation of Plant Thermomorphogenesis via BZR1.	Brassinosteroids	0-16	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	79-83
29337075-6	2018	Based on a mutagenesis screen in the model plant Arabidopsis thaliana for mutants with defects in temperature-induced hypocotyl elongation, we show here that both PIF4 and auxin function depend on brassinosteroids.	Brassinosteroids	197-213	phytochrome interacting factor 4	Arabidopsis thaliana	163-167
29337075-7	2018	Genetic and pharmacological analyses place brassinosteroids downstream of PIF4 and auxin.	Brassinosteroids	43-59	phytochrome interacting factor 4	Arabidopsis thaliana	74-78
29337075-8	2018	We found that brassinosteroids act via the transcription factor BRASSINAZOLE RESISTANT 1 (BZR1), which accumulates in the nucleus at high temperature, where it induces expression of growth-promoting genes.	Brassinosteroids	14-30	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	64-88
29337075-8	2018	We found that brassinosteroids act via the transcription factor BRASSINAZOLE RESISTANT 1 (BZR1), which accumulates in the nucleus at high temperature, where it induces expression of growth-promoting genes.	Brassinosteroids	14-30	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	90-94
29084267-3	2017	In this study, we produced transgenic creeping bentgrass (Agrostis stolonifera L.) overexpressing a BR-inactivating enzyme, Arabidopsis thaliana BR-related acyltransferase 1 (AtBAT1), which is known to catalyze the conversion of BR intermediates to inactive acylated conjugates.	Brassinosteroids	100-102	bidirectional amino acid transporter 1	Arabidopsis thaliana	175-181
29375601-0	2017	Arabidopsis G-Protein beta Subunit AGB1 Interacts with BES1 to Regulate Brassinosteroid Signaling and Cell Elongation.	Brassinosteroids	72-87	GTP binding protein beta 1	Arabidopsis thaliana	35-39
29375601-0	2017	Arabidopsis G-Protein beta Subunit AGB1 Interacts with BES1 to Regulate Brassinosteroid Signaling and Cell Elongation.	Brassinosteroids	72-87	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	55-59
29375601-4	2017	An AGB1-null mutant, agb1-2, displays BR hyposensitivity and brassinazole (BRZ, BR biosynthesis inhibitor) hypersensitivity, which suggests that AGB1 positively mediates the BR signaling pathway.	Brassinosteroids	38-40	GTP binding protein beta 1	Arabidopsis thaliana	3-7
29375601-4	2017	An AGB1-null mutant, agb1-2, displays BR hyposensitivity and brassinazole (BRZ, BR biosynthesis inhibitor) hypersensitivity, which suggests that AGB1 positively mediates the BR signaling pathway.	Brassinosteroids	38-40	GTP binding protein beta 1	Arabidopsis thaliana	21-25
29375601-4	2017	An AGB1-null mutant, agb1-2, displays BR hyposensitivity and brassinazole (BRZ, BR biosynthesis inhibitor) hypersensitivity, which suggests that AGB1 positively mediates the BR signaling pathway.	Brassinosteroids	38-40	GTP binding protein beta 1	Arabidopsis thaliana	145-149
28887625-3	2018	Here, the brassinosteroid-responsive RING-H2 (BRH1) gene, which is suppressed by 24-epi-brassinolide treatment, was isolated from Arabidopsis thaliana.	Brassinosteroids	10-25	brassinosteroid-responsive RING-H2	Arabidopsis thaliana	46-50
28865087-5	2017	PUB30 specifically interacted with BRI1 kinase inhibitor 1 (BKI1), a regulator playing dual roles in brassinosteroids signaling, in vitro and in vivo.	Brassinosteroids	101-117	BRI1 kinase inhibitor 1	Arabidopsis thaliana	35-58
28865087-5	2017	PUB30 specifically interacted with BRI1 kinase inhibitor 1 (BKI1), a regulator playing dual roles in brassinosteroids signaling, in vitro and in vivo.	Brassinosteroids	101-117	BRI1 kinase inhibitor 1	Arabidopsis thaliana	60-64
29021807-0	2017	C4 Protein of Sweet Potato Leaf Curl Virus Regulates Brassinosteroid Signaling Pathway through Interaction with AtBIN2 and Affects Male Fertility in Arabidopsis.	Brassinosteroids	53-68	Protein kinase superfamily protein	Arabidopsis thaliana	112-118
29028796-1	2017	The rapid alkalinization factor (RALF) peptide negatively regulates cell expansion, and an antagonistic relationship has been demonstrated between AtRALF1, a root-specific RALF isoform in Arabidopsis, and brassinosteroids (BRs).	Brassinosteroids	205-221	rapid alkalinization factor 1	Arabidopsis thaliana	147-154
29021807-4	2017	Using bimolecular fluorescence complementation analysis, this study demonstrated that the SPLCV-JS C4 protein interacted with brassinosteroid-insensitive 2 (AtBIN2) in the plasma membrane of Nicotiana benthamiana cells.	Brassinosteroids	126-141	Protein kinase superfamily protein	Arabidopsis thaliana	157-163
29021807-6	2017	This interaction led to the re-localization of AtBIN2-interacting proteins AtBES1/AtBZR1 into the nucleus which altered the expression of brassinosteroid (BR)-response genes, resulting in the activation of BR-signaling pathway.	Brassinosteroids	138-153	Protein kinase superfamily protein	Arabidopsis thaliana	47-53
29021807-6	2017	This interaction led to the re-localization of AtBIN2-interacting proteins AtBES1/AtBZR1 into the nucleus which altered the expression of brassinosteroid (BR)-response genes, resulting in the activation of BR-signaling pathway.	Brassinosteroids	138-153	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	75-81
29021807-6	2017	This interaction led to the re-localization of AtBIN2-interacting proteins AtBES1/AtBZR1 into the nucleus which altered the expression of brassinosteroid (BR)-response genes, resulting in the activation of BR-signaling pathway.	Brassinosteroids	138-153	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	82-88
28839160-2	2017	Brassinosteroids Insensitive 1 (BRI1) is required for BR perception and initiation of subsequent signal transduction in Arabidopsis.	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	32-36
28848587-1	2017	Brassinosteroids (BRs) play important roles in plant growth, development, and stress responses through the receptor, Brassinosteroid-insensitive 1 (BRI1), which perceives BRs and initiates BR signaling.	Brassinosteroids	0-16	brassinosteroid LRR receptor kinase	Solanum lycopersicum	117-152
28808238-7	2017	After priming, BR-deficient mutants cyp85a1/a2 and det2 showed significantly longer longevity than the wild type (WT).	Brassinosteroids	15-17	brassinosteroid-6-oxidase 1	Arabidopsis thaliana	36-43
28827608-8	2017	Increased growth temperature specifically impacts on the level of the brassinosteroid receptor BRI1 to downregulate brassinosteroid signaling and mediate root elongation.	Brassinosteroids	70-85	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	95-99
28827608-9	2017	Our results establish that BRI1 integrates temperature and brassinosteroid signaling to regulate root growth upon long-term changes in environmental conditions associated with global warming.Moderate heat stimulates the growth of Arabidopsis shoots in an auxin-dependent manner.	Brassinosteroids	59-74	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	27-31
28848587-1	2017	Brassinosteroids (BRs) play important roles in plant growth, development, and stress responses through the receptor, Brassinosteroid-insensitive 1 (BRI1), which perceives BRs and initiates BR signaling.	Brassinosteroids	18-21	brassinosteroid LRR receptor kinase	Solanum lycopersicum	117-152
28848587-7	2017	An increased BR signaling intensity mediated by SlBRI1 overexpression was therefore positively correlated with carotenoid accumulation and fruit nutritional quality.	Brassinosteroids	13-15	brassinosteroid LRR receptor kinase	Solanum lycopersicum	48-54
28720789-2	2017	To investigate the mechanisms of BR signaling, we previously used the BR biosynthesis inhibitor Brz as a chemical biology tool and identified the Brz-insensitive-long hypocotyl4 mutant (bil4).	Brassinosteroids	33-35	Bax inhibitor-1 family protein	Arabidopsis thaliana	186-190
28718794-1	2017	The BRS1 (BRI1 Suppressor 1) gene encodes a serine carboxypeptidase that plays a critical role in the brassinosteroid signaling pathway.	Brassinosteroids	102-117	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	4-8
28718794-1	2017	The BRS1 (BRI1 Suppressor 1) gene encodes a serine carboxypeptidase that plays a critical role in the brassinosteroid signaling pathway.	Brassinosteroids	102-117	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	10-27
28720789-2	2017	To investigate the mechanisms of BR signaling, we previously used the BR biosynthesis inhibitor Brz as a chemical biology tool and identified the Brz-insensitive-long hypocotyl4 mutant (bil4).	Brassinosteroids	70-72	Bax inhibitor-1 family protein	Arabidopsis thaliana	186-190
28461403-2	2017	BRASSINOSTEROID INSENSITIVE1 (BRI1), a multidomain transmembrane receptor-like kinase, is a major receptor of brassinosteroids in Arabidopsis (Arabidopsis thaliana).	Brassinosteroids	0-15	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	30-34
28461403-2	2017	BRASSINOSTEROID INSENSITIVE1 (BRI1), a multidomain transmembrane receptor-like kinase, is a major receptor of brassinosteroids in Arabidopsis (Arabidopsis thaliana).	Brassinosteroids	110-126	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	30-34
28438793-0	2017	Brassinosteroid Biosynthesis Is Modulated via a Transcription Factor Cascade of COG1, PIF4, and PIF5.	Brassinosteroids	0-15	Disease resistance protein (TIR-NBS-LRR class) family	Arabidopsis thaliana	80-84
28575660-5	2017	KIB1 directly interacted with BIN2 in a BR-dependent manner and promoted BIN2 ubiquitination in vitro.	Brassinosteroids	40-42	Protein kinase superfamily protein	Arabidopsis thaliana	30-34
28507175-5	2017	Notably, application of brassinosteroids (BRs) partly rescued the stomatal leaf phenotype of spch-5 Transcriptomic analysis combining spch-5 with BR treatments revealed that the expression of a set of SPCH target genes was restored by BRs.	Brassinosteroids	42-45	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	93-97
28507175-5	2017	Notably, application of brassinosteroids (BRs) partly rescued the stomatal leaf phenotype of spch-5 Transcriptomic analysis combining spch-5 with BR treatments revealed that the expression of a set of SPCH target genes was restored by BRs.	Brassinosteroids	42-45	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	134-138
28586421-4	2017	Among the direct targets of FUL, we identified SMALL AUXIN UPREGULATED RNA 10 (SAUR10), a growth regulator that is highly induced by a combination of auxin and brassinosteroids and in response to reduced R:FR light.	Brassinosteroids	160-176	AGAMOUS-like 8	Arabidopsis thaliana	28-31
28586421-4	2017	Among the direct targets of FUL, we identified SMALL AUXIN UPREGULATED RNA 10 (SAUR10), a growth regulator that is highly induced by a combination of auxin and brassinosteroids and in response to reduced R:FR light.	Brassinosteroids	160-176	SAUR-like auxin-responsive protein family	Arabidopsis thaliana	47-77
28586421-4	2017	Among the direct targets of FUL, we identified SMALL AUXIN UPREGULATED RNA 10 (SAUR10), a growth regulator that is highly induced by a combination of auxin and brassinosteroids and in response to reduced R:FR light.	Brassinosteroids	160-176	SAUR-like auxin-responsive protein family	Arabidopsis thaliana	79-85
28507175-5	2017	Notably, application of brassinosteroids (BRs) partly rescued the stomatal leaf phenotype of spch-5 Transcriptomic analysis combining spch-5 with BR treatments revealed that the expression of a set of SPCH target genes was restored by BRs.	Brassinosteroids	42-45	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	201-205
28507175-6	2017	Our results also show that BR-dependent stomata formation and expression of some, but not all, SPCH target genes require the integrity of the bHLH domain of SPCH.	Brassinosteroids	27-29	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	95-99
28438793-0	2017	Brassinosteroid Biosynthesis Is Modulated via a Transcription Factor Cascade of COG1, PIF4, and PIF5.	Brassinosteroids	0-15	phytochrome interacting factor 4	Arabidopsis thaliana	86-90
28507175-6	2017	Our results also show that BR-dependent stomata formation and expression of some, but not all, SPCH target genes require the integrity of the bHLH domain of SPCH.	Brassinosteroids	27-29	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	157-161
28438793-0	2017	Brassinosteroid Biosynthesis Is Modulated via a Transcription Factor Cascade of COG1, PIF4, and PIF5.	Brassinosteroids	0-15	phytochrome interacting factor 3-like 6	Arabidopsis thaliana	96-100
28438793-6	2017	A BR profile assay indicated that BR levels are elevated in cog1-3D seedlings.	Brassinosteroids	2-4	Disease resistance protein (TIR-NBS-LRR class) family	Arabidopsis thaliana	60-64
28438793-7	2017	Quantitative reverse transcription-polymerase chain reaction analyses showed that several key BR biosynthetic genes are significantly up-regulated in cog1-3D compared with those of the wild type.	Brassinosteroids	94-96	Disease resistance protein (TIR-NBS-LRR class) family	Arabidopsis thaliana	150-154
28438793-8	2017	Two basic helix-loop-helix transcription factors, PIF4 and PIF5, were found to be transcriptionally up-regulated in cog1-3D Genetic analysis indicated that PIF4 and PIF5 were required for COG1 to promote BR biosynthesis and hypocotyl elongation.	Brassinosteroids	204-206	phytochrome interacting factor 4	Arabidopsis thaliana	50-54
28438793-8	2017	Two basic helix-loop-helix transcription factors, PIF4 and PIF5, were found to be transcriptionally up-regulated in cog1-3D Genetic analysis indicated that PIF4 and PIF5 were required for COG1 to promote BR biosynthesis and hypocotyl elongation.	Brassinosteroids	204-206	phytochrome interacting factor 3-like 6	Arabidopsis thaliana	59-63
28438793-8	2017	Two basic helix-loop-helix transcription factors, PIF4 and PIF5, were found to be transcriptionally up-regulated in cog1-3D Genetic analysis indicated that PIF4 and PIF5 were required for COG1 to promote BR biosynthesis and hypocotyl elongation.	Brassinosteroids	204-206	Disease resistance protein (TIR-NBS-LRR class) family	Arabidopsis thaliana	116-120
28438793-8	2017	Two basic helix-loop-helix transcription factors, PIF4 and PIF5, were found to be transcriptionally up-regulated in cog1-3D Genetic analysis indicated that PIF4 and PIF5 were required for COG1 to promote BR biosynthesis and hypocotyl elongation.	Brassinosteroids	204-206	phytochrome interacting factor 4	Arabidopsis thaliana	156-160
28438793-8	2017	Two basic helix-loop-helix transcription factors, PIF4 and PIF5, were found to be transcriptionally up-regulated in cog1-3D Genetic analysis indicated that PIF4 and PIF5 were required for COG1 to promote BR biosynthesis and hypocotyl elongation.	Brassinosteroids	204-206	phytochrome interacting factor 3-like 6	Arabidopsis thaliana	165-169
28438793-8	2017	Two basic helix-loop-helix transcription factors, PIF4 and PIF5, were found to be transcriptionally up-regulated in cog1-3D Genetic analysis indicated that PIF4 and PIF5 were required for COG1 to promote BR biosynthesis and hypocotyl elongation.	Brassinosteroids	204-206	Disease resistance protein (TIR-NBS-LRR class) family	Arabidopsis thaliana	188-192
28438793-9	2017	Chromatin immunoprecipitation and electrophoretic mobility shift assays indicated that COG1 binds to the promoter regions of PIF4 and PIF5, and PIF4 and PIF5 bind to the promoter regions of key BR biosynthetic genes, such as DWF4 and BR6ox2, to directly promote their expression.	Brassinosteroids	194-196	phytochrome interacting factor 4	Arabidopsis thaliana	144-148
28438793-9	2017	Chromatin immunoprecipitation and electrophoretic mobility shift assays indicated that COG1 binds to the promoter regions of PIF4 and PIF5, and PIF4 and PIF5 bind to the promoter regions of key BR biosynthetic genes, such as DWF4 and BR6ox2, to directly promote their expression.	Brassinosteroids	194-196	phytochrome interacting factor 3-like 6	Arabidopsis thaliana	153-157
28438793-10	2017	These results demonstrated that COG1 regulates BR biosynthesis via up-regulating the transcription of PIF4 and PIF5.	Brassinosteroids	47-49	Disease resistance protein (TIR-NBS-LRR class) family	Arabidopsis thaliana	32-36
28438793-10	2017	These results demonstrated that COG1 regulates BR biosynthesis via up-regulating the transcription of PIF4 and PIF5.	Brassinosteroids	47-49	phytochrome interacting factor 4	Arabidopsis thaliana	102-106
28438793-10	2017	These results demonstrated that COG1 regulates BR biosynthesis via up-regulating the transcription of PIF4 and PIF5.	Brassinosteroids	47-49	phytochrome interacting factor 3-like 6	Arabidopsis thaliana	111-115
28507175-0	2017	A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development.	Brassinosteroids	74-76	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	37-41
28507175-5	2017	Notably, application of brassinosteroids (BRs) partly rescued the stomatal leaf phenotype of spch-5 Transcriptomic analysis combining spch-5 with BR treatments revealed that the expression of a set of SPCH target genes was restored by BRs.	Brassinosteroids	24-40	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	93-97
28507175-5	2017	Notably, application of brassinosteroids (BRs) partly rescued the stomatal leaf phenotype of spch-5 Transcriptomic analysis combining spch-5 with BR treatments revealed that the expression of a set of SPCH target genes was restored by BRs.	Brassinosteroids	24-40	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	134-138
28507175-5	2017	Notably, application of brassinosteroids (BRs) partly rescued the stomatal leaf phenotype of spch-5 Transcriptomic analysis combining spch-5 with BR treatments revealed that the expression of a set of SPCH target genes was restored by BRs.	Brassinosteroids	24-40	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	201-205
28326087-0	2017	Arabidopsis NAC Transcription Factor JUNGBRUNNEN1 Exerts Conserved Control Over Gibberellin and Brassinosteroid Metabolism and Signaling Genes in Tomato.	Brassinosteroids	96-111	NAC domain containing protein 42	Arabidopsis thaliana	37-49
28545052-2	2017	Brassinosteroid insensitive 1 (BRI1) LIKE3 (BRL3) phosphorylates AtRGS1 in vitro.	Brassinosteroids	0-15	REGULATOR OF G-PROTEIN SIGNALING 1	Arabidopsis thaliana	65-71
28500288-4	2017	DWF4 is one of the main enzymes involved in the BR biosynthesis pathway in Arabidopsis thaliana.	Brassinosteroids	48-50	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-4
28487714-1	2017	Receptor-like kinases BAK1 and BKK1 modulate multiple cellular processes including brassinosteroid signaling and PRR-mediated PTI in Arabidopsis.	Brassinosteroids	83-98	BRI1-associated receptor kinase	Arabidopsis thaliana	22-26
28487714-1	2017	Receptor-like kinases BAK1 and BKK1 modulate multiple cellular processes including brassinosteroid signaling and PRR-mediated PTI in Arabidopsis.	Brassinosteroids	83-98	somatic embryogenesis receptor-like kinase 4	Arabidopsis thaliana	31-35
28289192-2	2017	Here, we demonstrate that the protein kinase BRASSINOSTEROID INSENSITIVE2 (BIN2), a key negative regulator of brassinosteroid (BR) signaling, can phosphorylate Arabidopsis cellulose synthase A1 (CESA1), a subunit of the primary cell wall cellulose synthase complex, and thereby negatively regulate cellulose biosynthesis.	Brassinosteroids	45-60	Protein kinase superfamily protein	Arabidopsis thaliana	75-79
28289192-2	2017	Here, we demonstrate that the protein kinase BRASSINOSTEROID INSENSITIVE2 (BIN2), a key negative regulator of brassinosteroid (BR) signaling, can phosphorylate Arabidopsis cellulose synthase A1 (CESA1), a subunit of the primary cell wall cellulose synthase complex, and thereby negatively regulate cellulose biosynthesis.	Brassinosteroids	45-60	cellulose synthase 1	Arabidopsis thaliana	172-193
28289192-2	2017	Here, we demonstrate that the protein kinase BRASSINOSTEROID INSENSITIVE2 (BIN2), a key negative regulator of brassinosteroid (BR) signaling, can phosphorylate Arabidopsis cellulose synthase A1 (CESA1), a subunit of the primary cell wall cellulose synthase complex, and thereby negatively regulate cellulose biosynthesis.	Brassinosteroids	45-60	cellulose synthase 1	Arabidopsis thaliana	195-200
28326087-6	2017	The fact that AtJUB1 exerts an inhibitory effect on the GA/BR biosynthesis and PIF4 genes but acts as a direct activator of DELLA genes in both, Arabidopsis and tomato, strongly supports the model that the molecular constituents of the JUNGBRUNNEN1 growth control module are considerably conserved across species.	Brassinosteroids	59-61	NAC domain containing protein 42	Arabidopsis thaliana	14-20
28176007-9	2017	All the genes were significantly regulated in response to auxin, whereas only GhMADS3, GhMADS4 and GhMADS7 genes were also regulated by brassinosteroid treatment.	Brassinosteroids	136-151	floral homeotic protein AGAMOUS-like	Gossypium hirsutum	78-85
27940271-4	2017	Expression of the NtEXGT gene in leaves was induced by cytokinins, auxins, brassinosteroids and gibberellins.	Brassinosteroids	75-91	probable xyloglucan endotransglucosylase/hydrolase protein	Nicotiana tabacum	18-24
27988365-3	2017	BKI1 is the only reported inhibitor of receptor kinases in Arabidopsis, which negatively regulates BRI1 in the brassinosteroid pathway.	Brassinosteroids	111-126	BRI1 kinase inhibitor 1	Arabidopsis thaliana	0-4
27988365-3	2017	BKI1 is the only reported inhibitor of receptor kinases in Arabidopsis, which negatively regulates BRI1 in the brassinosteroid pathway.	Brassinosteroids	111-126	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	99-103
28138331-3	2016	Identification of intermediate signaling mutants such as bri1-5 and bri1-9 has contributed drastically to the elucidation of BR signaling pathway using both genetic and biochemical approaches.	Brassinosteroids	125-127	integral membrane protein 2B	Homo sapiens	57-74
28096215-1	2017	Brassinosteroids (BRs) trigger an intracellular signaling cascade through its receptors BR INSENSITIVE 1 (BRI1), BRI1-LIKE 1 (BRL1) and BRL3.	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	88-110
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	120-148
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	150-154
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	0-16	BRI1-associated receptor kinase	Arabidopsis thaliana	176-245
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	0-16	BRI1-associated receptor kinase	Arabidopsis thaliana	247-252
28096215-1	2017	Brassinosteroids (BRs) trigger an intracellular signaling cascade through its receptors BR INSENSITIVE 1 (BRI1), BRI1-LIKE 1 (BRL1) and BRL3.	Brassinosteroids	0-16	BRI1 like	Arabidopsis thaliana	113-124
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	0-16	BRI1-associated receptor kinase	Arabidopsis thaliana	253-257
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	120-148
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	150-154
28096215-1	2017	Brassinosteroids (BRs) trigger an intracellular signaling cascade through its receptors BR INSENSITIVE 1 (BRI1), BRI1-LIKE 1 (BRL1) and BRL3.	Brassinosteroids	0-16	BRI1 like	Arabidopsis thaliana	126-130
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	18-21	BRI1-associated receptor kinase	Arabidopsis thaliana	176-245
28096215-1	2017	Brassinosteroids (BRs) trigger an intracellular signaling cascade through its receptors BR INSENSITIVE 1 (BRI1), BRI1-LIKE 1 (BRL1) and BRL3.	Brassinosteroids	0-16	BRI1-like 3	Arabidopsis thaliana	136-140
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	18-21	BRI1-associated receptor kinase	Arabidopsis thaliana	247-252
28114413-1	2017	Brassinosteroids (BRs) are plant hormones that are perceived at the plasma membrane (PM) by the ligand binding receptor BRASSINOSTEROID-INSENSITIVE1 (BRI1) and the co-receptor SOMATIC EMBRYOGENESIS RECEPTOR LIKE KINASE 3/BRI1 ASSOCIATED KINASE 1 (SERK3/BAK1).	Brassinosteroids	18-21	BRI1-associated receptor kinase	Arabidopsis thaliana	253-257
28096215-1	2017	Brassinosteroids (BRs) trigger an intracellular signaling cascade through its receptors BR INSENSITIVE 1 (BRI1), BRI1-LIKE 1 (BRL1) and BRL3.	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	88-110
28096215-1	2017	Brassinosteroids (BRs) trigger an intracellular signaling cascade through its receptors BR INSENSITIVE 1 (BRI1), BRI1-LIKE 1 (BRL1) and BRL3.	Brassinosteroids	18-21	BRI1 like	Arabidopsis thaliana	113-124
28096215-1	2017	Brassinosteroids (BRs) trigger an intracellular signaling cascade through its receptors BR INSENSITIVE 1 (BRI1), BRI1-LIKE 1 (BRL1) and BRL3.	Brassinosteroids	18-21	BRI1 like	Arabidopsis thaliana	126-130
28096215-1	2017	Brassinosteroids (BRs) trigger an intracellular signaling cascade through its receptors BR INSENSITIVE 1 (BRI1), BRI1-LIKE 1 (BRL1) and BRL3.	Brassinosteroids	18-21	BRI1-like 3	Arabidopsis thaliana	136-140
28695957-2	2017	In Arabidopsis thaliana, brassinosteroids, which function upstream of the TTG/bHLHs/MYBs/GL2 transcriptional network, positively regulate stomatal formation in the hypocotyl.	Brassinosteroids	25-41	Transducin/WD40 repeat-like superfamily protein	Arabidopsis thaliana	74-77
28061864-5	2017	Through bioinformatics analysis, we identified a list of putative homologs of genes known to be involved in BR biosynthesis and signaling in Arabidopsis, such as DWF4, BR6OX2, CPD, BRI1, and BIN2.	Brassinosteroids	108-110	Cytochrome P450 superfamily protein	Arabidopsis thaliana	162-166
28061864-5	2017	Through bioinformatics analysis, we identified a list of putative homologs of genes known to be involved in BR biosynthesis and signaling in Arabidopsis, such as DWF4, BR6OX2, CPD, BRI1, and BIN2.	Brassinosteroids	108-110	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	168-174
28061864-5	2017	Through bioinformatics analysis, we identified a list of putative homologs of genes known to be involved in BR biosynthesis and signaling in Arabidopsis, such as DWF4, BR6OX2, CPD, BRI1, and BIN2.	Brassinosteroids	108-110	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	181-185
28061864-5	2017	Through bioinformatics analysis, we identified a list of putative homologs of genes known to be involved in BR biosynthesis and signaling in Arabidopsis, such as DWF4, BR6OX2, CPD, BRI1, and BIN2.	Brassinosteroids	108-110	Protein kinase superfamily protein	Arabidopsis thaliana	191-195
28695957-2	2017	In Arabidopsis thaliana, brassinosteroids, which function upstream of the TTG/bHLHs/MYBs/GL2 transcriptional network, positively regulate stomatal formation in the hypocotyl.	Brassinosteroids	25-41	HD-ZIP IV family of homeobox-leucine zipper protein with lipid-binding START domain-containing protein	Arabidopsis thaliana	89-92
27523280-2	2016	BZS1 is a B-box zinc finger protein previously characterized as a negative regulator in the brassinosteroid (BR)-signaling pathway and a positive regulator in the light-signaling pathway.	Brassinosteroids	92-107	B-box zinc finger family protein	Arabidopsis thaliana	0-4
27794018-7	2017	Themes covered vary, from interactions between HD-ZIP IIIs and auxin, cytokinin, and brassinosteroids, to the requirement for exquisite spatial and temporal regulation of HD-ZIP III expression through miRNA-mediated post-transcriptional regulation, and interactions with other transcription factors.	Brassinosteroids	85-101	death associated protein kinase 3	Homo sapiens	50-53
27966492-0	2016	Functional analyses of Populus euphratica brassinosteroid biosynthesis enzyme genes DWF4 (PeDWF4) and CPD (PeCPD) in the regulation of growth and development of Arabidopsis thaliana.	Brassinosteroids	42-57	cytochrome P450 90B1-like	Populus euphratica	84-88
27966492-1	2016	DWF4 and CPD are key brassinosteroids (BRs) biosynthesis enzyme genes.	Brassinosteroids	21-37	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-4
27966492-1	2016	DWF4 and CPD are key brassinosteroids (BRs) biosynthesis enzyme genes.	Brassinosteroids	39-42	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-4
28018412-8	2016	Components of auxin, cytokinin, gibberellic acid, jasmonate and brassinosteroid signaling and metabolism pathways were shown to take part in ABI5 regulation and/or to be regulated by ABI5.	Brassinosteroids	64-79	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	141-145
28018412-8	2016	Components of auxin, cytokinin, gibberellic acid, jasmonate and brassinosteroid signaling and metabolism pathways were shown to take part in ABI5 regulation and/or to be regulated by ABI5.	Brassinosteroids	64-79	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	183-187
27803191-3	2016	For example, serk1serk3 double mutant roots are insensitive toward brassinosteroids but have a phenotype different from bri1 mutant roots.	Brassinosteroids	67-83	somatic embryogenesis receptor-like kinase 1	Arabidopsis thaliana	13-23
27523280-2	2016	BZS1 is a B-box zinc finger protein previously characterized as a negative regulator in the brassinosteroid (BR)-signaling pathway and a positive regulator in the light-signaling pathway.	Brassinosteroids	109-111	B-box zinc finger family protein	Arabidopsis thaliana	0-4
27523280-8	2016	In contrast to BR, strigolactone (SL) increases BZS1 level, whereas the SL responses of hypocotyl elongation, chlorophyll and HY5 accumulation are diminished in the BZS1-SRDX seedlings, indicating that BZS1 is involved in these SL responses.	Brassinosteroids	15-17	B-box zinc finger family protein	Arabidopsis thaliana	165-169
27523280-8	2016	In contrast to BR, strigolactone (SL) increases BZS1 level, whereas the SL responses of hypocotyl elongation, chlorophyll and HY5 accumulation are diminished in the BZS1-SRDX seedlings, indicating that BZS1 is involved in these SL responses.	Brassinosteroids	15-17	B-box zinc finger family protein	Arabidopsis thaliana	165-169
27597774-3	2016	Here, we show that the miR319-regulated TCP (TEOSINTE BRANCHED1, CYCLODEA, PROLIFERATING CELL FACTORS) transcription factors, notably TCP4, directly activate YUCCA5 transcription and integrate the auxin response to a brassinosteroid-dependent molecular circuit that promotes cell elongation in Arabidopsis thaliana hypocotyls.	Brassinosteroids	217-232	TCP family transcription factor 4	Arabidopsis thaliana	134-138
27562168-0	2016	Histone deacetylase HDA6 enhances brassinosteroid signaling by inhibiting the BIN2 kinase.	Brassinosteroids	34-49	histone deacetylase 6	Arabidopsis thaliana	20-24
27562168-0	2016	Histone deacetylase HDA6 enhances brassinosteroid signaling by inhibiting the BIN2 kinase.	Brassinosteroids	34-49	Protein kinase superfamily protein	Arabidopsis thaliana	78-82
27562168-4	2016	The hda6 mutant showed a BR-repressed phenotype in the dark and was less sensitive to BR biosynthesis inhibitors.	Brassinosteroids	25-27	histone deacetylase 6	Arabidopsis thaliana	4-8
27597774-4	2016	Furthermore, TCP4 modulates the common transcriptional network downstream to auxin-brassinosteroid signaling, which is also triggered by environmental cues, such as light, to promote cell expansion.	Brassinosteroids	83-98	TCP family transcription factor 4	Arabidopsis thaliana	13-17
27511026-6	2016	Physiological and genetic analysis show a BR-dependent expression of BRL3 in the root meristem.	Brassinosteroids	42-44	BRI1-like 3	Arabidopsis thaliana	69-73
27597774-3	2016	Here, we show that the miR319-regulated TCP (TEOSINTE BRANCHED1, CYCLODEA, PROLIFERATING CELL FACTORS) transcription factors, notably TCP4, directly activate YUCCA5 transcription and integrate the auxin response to a brassinosteroid-dependent molecular circuit that promotes cell elongation in Arabidopsis thaliana hypocotyls.	Brassinosteroids	217-232	Flavin-binding monooxygenase family protein	Arabidopsis thaliana	158-164
27288361-0	2016	nana plant2 Encodes a Maize Ortholog of the Arabidopsis Brassinosteroid Biosynthesis Gene DWARF1, Identifying Developmental Interactions between Brassinosteroids and Gibberellins.	Brassinosteroids	145-161	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	90-96
27354416-6	2016	MAKR5 belongs to a small protein family whose prototypical member, BRI1 KINASE INHIBITOR 1, is an essentially negative regulator of brassinosteroid signaling.	Brassinosteroids	132-147	membrane-associated kinase regulator	Arabidopsis thaliana	0-5
27354416-6	2016	MAKR5 belongs to a small protein family whose prototypical member, BRI1 KINASE INHIBITOR 1, is an essentially negative regulator of brassinosteroid signaling.	Brassinosteroids	132-147	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	67-71
27432888-9	2016	Importantly, TT8 affects stress response, along with brassinosteroid and jasmonic acid biosynthesis, by directly binding to the promoters of key genes of these processes.	Brassinosteroids	53-68	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	13-16
27345161-4	2016	Here, we show that sugar signaling through TOR controls the accumulation of the brassinosteroid (BR)-signaling transcription factor BZR1, which is essential for growth promotion by multiple hormonal and environmental signals [8-11].	Brassinosteroids	80-95	target of rapamycin	Arabidopsis thaliana	43-46
27345161-4	2016	Here, we show that sugar signaling through TOR controls the accumulation of the brassinosteroid (BR)-signaling transcription factor BZR1, which is essential for growth promotion by multiple hormonal and environmental signals [8-11].	Brassinosteroids	80-95	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	132-136
27446127-6	2016	Moreover, BAK1 (BRASSINOSTEROID INSENSITIVE 1-associated kinase 1) RLK, which together with ERf/TMM regulates stomatal patterning and resistance to Pto, was also found to have an unequal contribution with ER in regulating immune responses and resistance to PcBMM.	Brassinosteroids	16-31	BRI1-associated receptor kinase	Arabidopsis thaliana	10-14
27455172-3	2016	Here, we show that CYP85A2, the cytochrome P450 enzyme that performs the last step in brassinosteroid biosynthesis (conversion of castasterone to brassinolide)(4), must be farnesylated to function in Arabidopsis.	Brassinosteroids	86-101	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	19-26
27446127-6	2016	Moreover, BAK1 (BRASSINOSTEROID INSENSITIVE 1-associated kinase 1) RLK, which together with ERf/TMM regulates stomatal patterning and resistance to Pto, was also found to have an unequal contribution with ER in regulating immune responses and resistance to PcBMM.	Brassinosteroids	16-31	receptor lectin kinase	Arabidopsis thaliana	67-70
27324083-0	2016	Overexpression of the brassinosteroid biosynthetic gene DWF4 in Brassica napus simultaneously increases seed yield and stress tolerance.	Brassinosteroids	22-37	Cytochrome P450 superfamily protein	Arabidopsis thaliana	56-60
27329140-12	2016	The PHYB-regulated genes were enriched in components of the auxin, gibberellin and brassinosteroid biosynthesis and signaling pathways, and in transcription factors with putative roles in regulating vegetative development and shade-avoidance responses.	Brassinosteroids	83-98	phytochrome B	Triticum aestivum	4-8
27014317-3	2016	Most recently, CRY1 N terminus (CNT1) has been found to be involved in CRY1 signaling independent of CCT1, and implicated in the inhibition of gibberellin acids (GA)/brassinosteroids (BR)/auxin-responsive gene expression.	Brassinosteroids	166-182	cryptochrome 1	Arabidopsis thaliana	15-19
27338344-9	2016	Ectopic over-expression of GmBRI1b in Arabidopsis BR receptor loss-of-function mutant (bri1-5 bak1-1D) restored hypocotyl growth in etiolated seedlings; increased the growth of stems, leaves, and siliques in light; and rescued the developmental defects in leaves of the bri1-6 mutant, and complemented the responses of BR biosynthesis-related genes in the bri1-5 bak1-D mutant grown in light.	Brassinosteroids	29-31	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	87-93
27338344-9	2016	Ectopic over-expression of GmBRI1b in Arabidopsis BR receptor loss-of-function mutant (bri1-5 bak1-1D) restored hypocotyl growth in etiolated seedlings; increased the growth of stems, leaves, and siliques in light; and rescued the developmental defects in leaves of the bri1-6 mutant, and complemented the responses of BR biosynthesis-related genes in the bri1-5 bak1-D mutant grown in light.	Brassinosteroids	29-31	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	270-276
27338344-9	2016	Ectopic over-expression of GmBRI1b in Arabidopsis BR receptor loss-of-function mutant (bri1-5 bak1-1D) restored hypocotyl growth in etiolated seedlings; increased the growth of stems, leaves, and siliques in light; and rescued the developmental defects in leaves of the bri1-6 mutant, and complemented the responses of BR biosynthesis-related genes in the bri1-5 bak1-D mutant grown in light.	Brassinosteroids	29-31	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	356-362
26808213-0	2016	Immunophilin-like FKBP42/TWISTED DWARF1 Interacts with the Receptor Kinase BRI1 to Regulate Brassinosteroid Signaling in Arabidopsis.	Brassinosteroids	92-107	FK506-binding protein 12	Arabidopsis thaliana	0-12
26808213-0	2016	Immunophilin-like FKBP42/TWISTED DWARF1 Interacts with the Receptor Kinase BRI1 to Regulate Brassinosteroid Signaling in Arabidopsis.	Brassinosteroids	92-107	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	18-24
26808213-0	2016	Immunophilin-like FKBP42/TWISTED DWARF1 Interacts with the Receptor Kinase BRI1 to Regulate Brassinosteroid Signaling in Arabidopsis.	Brassinosteroids	92-107	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	33-39
26808213-0	2016	Immunophilin-like FKBP42/TWISTED DWARF1 Interacts with the Receptor Kinase BRI1 to Regulate Brassinosteroid Signaling in Arabidopsis.	Brassinosteroids	92-107	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	75-79
26808213-3	2016	Using genetic, physiological, and immunological experiments, we show here that FKBP42/TWD1 is necessary for brassinosteroid (BR) signal transduction.	Brassinosteroids	108-123	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	79-85
26808213-3	2016	Using genetic, physiological, and immunological experiments, we show here that FKBP42/TWD1 is necessary for brassinosteroid (BR) signal transduction.	Brassinosteroids	108-123	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	86-90
26808213-4	2016	The twd1 mutant showed reduced BR sensitivity in growth responses and activation of the BZR1 transcription factor.	Brassinosteroids	31-33	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	4-8
26802250-5	2016	Further analyses indicated that TWD1 modulates the BR signal transduction not by altering ER quality control or protein abundance of BRI1; instead, TWD1 appears to be critical in BR-induced interaction of BRI1 and its co-receptor BAK1, as well as BR-induced phosphorylation of these two proteins.	Brassinosteroids	51-53	BCL2 antagonist/killer 1	Homo sapiens	230-234
27249348-1	2016	Gibberellins (GAs) and brassinosteroids (BRs) are important phytohormones that control plant development and responses to environmental cues by involving DELLA proteins and BRASSINAZOLE-RESISTANT1 (BZR1) respectively as key transcription factors.	Brassinosteroids	23-39	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	173-196
27249348-1	2016	Gibberellins (GAs) and brassinosteroids (BRs) are important phytohormones that control plant development and responses to environmental cues by involving DELLA proteins and BRASSINAZOLE-RESISTANT1 (BZR1) respectively as key transcription factors.	Brassinosteroids	23-39	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	198-202
26493403-3	2015	BR homeostasis is maintained in part by transcriptional feedback regulation loops that control the expression of key metabolic enzymes, including the BR-inactivating enzymes BAS1 (CYP734A1, formerly CYP72B1) and SOB7 (CYP72C1).	Brassinosteroids	0-2	Cytochrome P450 superfamily protein	Arabidopsis thaliana	174-178
26517938-1	2016	Brassinosteroid (BR) binding activates the receptor kinase BRI1 by inducing heterodimerization with its co-receptor kinase BAK1; however, the mechanisms that reversibly inactivate BRI1 remain unclear.	Brassinosteroids	0-15	BCL2 antagonist/killer 1	Homo sapiens	123-127
26517938-1	2016	Brassinosteroid (BR) binding activates the receptor kinase BRI1 by inducing heterodimerization with its co-receptor kinase BAK1; however, the mechanisms that reversibly inactivate BRI1 remain unclear.	Brassinosteroids	17-19	BCL2 antagonist/killer 1	Homo sapiens	123-127
26493403-3	2015	BR homeostasis is maintained in part by transcriptional feedback regulation loops that control the expression of key metabolic enzymes, including the BR-inactivating enzymes BAS1 (CYP734A1, formerly CYP72B1) and SOB7 (CYP72C1).	Brassinosteroids	0-2	Cytochrome P450 superfamily protein	Arabidopsis thaliana	199-206
26773002-5	2016	O-GlcNAcylation of the DELLA protein REPRESSOR OF ga1-3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4, JASMONATE-ZIM DOMAIN1, and BRASSINAZOLE-RESISTANT1 (BZR1)-that are key regulators in light, jasmonate, and brassinosteroid signaling pathways, respectively.	Brassinosteroids	263-278	GRAS family transcription factor family protein	Arabidopsis thaliana	37-55
26773002-5	2016	O-GlcNAcylation of the DELLA protein REPRESSOR OF ga1-3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4, JASMONATE-ZIM DOMAIN1, and BRASSINAZOLE-RESISTANT1 (BZR1)-that are key regulators in light, jasmonate, and brassinosteroid signaling pathways, respectively.	Brassinosteroids	263-278	GRAS family transcription factor family protein	Arabidopsis thaliana	57-60
26773002-5	2016	O-GlcNAcylation of the DELLA protein REPRESSOR OF ga1-3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4, JASMONATE-ZIM DOMAIN1, and BRASSINAZOLE-RESISTANT1 (BZR1)-that are key regulators in light, jasmonate, and brassinosteroid signaling pathways, respectively.	Brassinosteroids	263-278	GRAS family transcription factor family protein	Arabidopsis thaliana	71-74
26773002-5	2016	O-GlcNAcylation of the DELLA protein REPRESSOR OF ga1-3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4, JASMONATE-ZIM DOMAIN1, and BRASSINAZOLE-RESISTANT1 (BZR1)-that are key regulators in light, jasmonate, and brassinosteroid signaling pathways, respectively.	Brassinosteroids	263-278	phytochrome interacting factor 3	Arabidopsis thaliana	143-147
26773002-5	2016	O-GlcNAcylation of the DELLA protein REPRESSOR OF ga1-3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4, JASMONATE-ZIM DOMAIN1, and BRASSINAZOLE-RESISTANT1 (BZR1)-that are key regulators in light, jasmonate, and brassinosteroid signaling pathways, respectively.	Brassinosteroids	263-278	phytochrome interacting factor 4	Arabidopsis thaliana	150-154
26773002-5	2016	O-GlcNAcylation of the DELLA protein REPRESSOR OF ga1-3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4, JASMONATE-ZIM DOMAIN1, and BRASSINAZOLE-RESISTANT1 (BZR1)-that are key regulators in light, jasmonate, and brassinosteroid signaling pathways, respectively.	Brassinosteroids	263-278	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	183-206
26773002-5	2016	O-GlcNAcylation of the DELLA protein REPRESSOR OF ga1-3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4, JASMONATE-ZIM DOMAIN1, and BRASSINAZOLE-RESISTANT1 (BZR1)-that are key regulators in light, jasmonate, and brassinosteroid signaling pathways, respectively.	Brassinosteroids	263-278	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	208-212
26493403-3	2015	BR homeostasis is maintained in part by transcriptional feedback regulation loops that control the expression of key metabolic enzymes, including the BR-inactivating enzymes BAS1 (CYP734A1, formerly CYP72B1) and SOB7 (CYP72C1).	Brassinosteroids	0-2	cytochrome p450 72c1	Arabidopsis thaliana	212-216
26493403-3	2015	BR homeostasis is maintained in part by transcriptional feedback regulation loops that control the expression of key metabolic enzymes, including the BR-inactivating enzymes BAS1 (CYP734A1, formerly CYP72B1) and SOB7 (CYP72C1).	Brassinosteroids	150-152	Cytochrome P450 superfamily protein	Arabidopsis thaliana	174-178
26493403-3	2015	BR homeostasis is maintained in part by transcriptional feedback regulation loops that control the expression of key metabolic enzymes, including the BR-inactivating enzymes BAS1 (CYP734A1, formerly CYP72B1) and SOB7 (CYP72C1).	Brassinosteroids	150-152	Cytochrome P450 superfamily protein	Arabidopsis thaliana	180-188
26493403-3	2015	BR homeostasis is maintained in part by transcriptional feedback regulation loops that control the expression of key metabolic enzymes, including the BR-inactivating enzymes BAS1 (CYP734A1, formerly CYP72B1) and SOB7 (CYP72C1).	Brassinosteroids	150-152	Cytochrome P450 superfamily protein	Arabidopsis thaliana	199-206
26493403-9	2015	Moreover, the disruption of BAS1 and SOB7 abolishes the short-hypocotyl phenotype of ATAF2 loss-of-function seedlings in low fluence rate white light, demonstrating an ATAF2-mediated connection between BR catabolism and photomorphogenesis.	Brassinosteroids	202-204	Cytochrome P450 superfamily protein	Arabidopsis thaliana	28-32
26493403-9	2015	Moreover, the disruption of BAS1 and SOB7 abolishes the short-hypocotyl phenotype of ATAF2 loss-of-function seedlings in low fluence rate white light, demonstrating an ATAF2-mediated connection between BR catabolism and photomorphogenesis.	Brassinosteroids	202-204	cytochrome p450 72c1	Arabidopsis thaliana	37-41
26493403-9	2015	Moreover, the disruption of BAS1 and SOB7 abolishes the short-hypocotyl phenotype of ATAF2 loss-of-function seedlings in low fluence rate white light, demonstrating an ATAF2-mediated connection between BR catabolism and photomorphogenesis.	Brassinosteroids	202-204	NAC (No Apical Meristem) domain transcriptional regulator superfamily protein	Arabidopsis thaliana	85-90
26493403-9	2015	Moreover, the disruption of BAS1 and SOB7 abolishes the short-hypocotyl phenotype of ATAF2 loss-of-function seedlings in low fluence rate white light, demonstrating an ATAF2-mediated connection between BR catabolism and photomorphogenesis.	Brassinosteroids	202-204	NAC (No Apical Meristem) domain transcriptional regulator superfamily protein	Arabidopsis thaliana	168-173
26493403-3	2015	BR homeostasis is maintained in part by transcriptional feedback regulation loops that control the expression of key metabolic enzymes, including the BR-inactivating enzymes BAS1 (CYP734A1, formerly CYP72B1) and SOB7 (CYP72C1).	Brassinosteroids	0-2	Cytochrome P450 superfamily protein	Arabidopsis thaliana	180-188
26600518-1	2015	BAK1 is a co-receptor of BRI1 in early signaling pathways mediated by brassinosteroids (BRs) and is thought to play a major role in plant growth and development.	Brassinosteroids	70-86	BRI1-associated receptor kinase	Arabidopsis thaliana	0-4
26600518-1	2015	BAK1 is a co-receptor of BRI1 in early signaling pathways mediated by brassinosteroids (BRs) and is thought to play a major role in plant growth and development.	Brassinosteroids	88-91	BRI1-associated receptor kinase	Arabidopsis thaliana	0-4
26617622-2	2015	Previous reports have indicated that BRs can induce ethylene production and enhance alternative oxidase (AOX) pathway.	Brassinosteroids	37-40	ubiquinol oxidase 4, chloroplastic/chromoplastic	Cucumis sativus	84-103
26617621-2	2015	In the past few years, the growth-promoting hormones brassinosteroids (BR) have emerged as negative regulators of pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI), promoting growth at the expense of defense.	Brassinosteroids	53-69	YME1 like 1 ATPase	Homo sapiens	114-151
26617621-2	2015	In the past few years, the growth-promoting hormones brassinosteroids (BR) have emerged as negative regulators of pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI), promoting growth at the expense of defense.	Brassinosteroids	53-69	YME1 like 1 ATPase	Homo sapiens	153-157
26617621-4	2015	In this work, we describe that activation of PTI by the bacterial PAMP flg22 results in the reduced expression of BR biosynthetic genes.	Brassinosteroids	114-116	YME1 like 1 ATPase	Homo sapiens	66-70
26617622-2	2015	Previous reports have indicated that BRs can induce ethylene production and enhance alternative oxidase (AOX) pathway.	Brassinosteroids	37-40	ubiquinol oxidase 4, chloroplastic/chromoplastic	Cucumis sativus	105-108
26233893-1	2015	Our previous studies indicated that TCP1 is a positive regulator of the brassinosteroid (BR) biosynthesis pathway by mediating the transcription of DWF4, one of the key BR biosynthetic genes in Arabidopsis thaliana.	Brassinosteroids	72-87	T-complex protein 1 alpha subunit	Arabidopsis thaliana	36-40
26387715-5	2015	Here, we demonstrate a role for OPS as a positive regulator of the brassinosteroid (BR) signaling pathway.	Brassinosteroids	67-82	LOW protein: UPF0503-like protein, putative (DUF740)	Arabidopsis thaliana	32-35
25998528-1	2015	MAIN CONCLUSION: Brassinosteroid is necessary for sugar promotion of Arabidopsis hypocotyl elongation in darkness, and sugar positively regulates BRASSINAZOLE RESISTANT1 (BZR1) at both transcription and protein levels.	Brassinosteroids	17-32	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	171-175
25896454-6	2015	These results suggest that BR promotes the partitioning of BRI1 into functional membrane microdomains to activate BR signaling.	Brassinosteroids	27-29	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	59-63
26417008-0	2015	9-Lipoxygenase-Derived Oxylipins Activate Brassinosteroid Signaling to Promote Cell Wall-Based Defense and Limit Pathogen Infection.	Brassinosteroids	42-57	lipoxygenase 1	Arabidopsis thaliana	2-14
26528315-3	2015	SERK1, SERK2, SERK3/BAK1, and SERK4/BKK1 have been well characterized to function as crucial regulators in multiple physiological processes such as brassinosteroid signaling, cell death control, pathogenesis, and pollen development.	Brassinosteroids	148-163	somatic embryogenesis receptor-like kinase 1	Arabidopsis thaliana	0-5
26528315-3	2015	SERK1, SERK2, SERK3/BAK1, and SERK4/BKK1 have been well characterized to function as crucial regulators in multiple physiological processes such as brassinosteroid signaling, cell death control, pathogenesis, and pollen development.	Brassinosteroids	148-163	somatic embryogenesis receptor-like kinase 2	Arabidopsis thaliana	7-12
26528315-3	2015	SERK1, SERK2, SERK3/BAK1, and SERK4/BKK1 have been well characterized to function as crucial regulators in multiple physiological processes such as brassinosteroid signaling, cell death control, pathogenesis, and pollen development.	Brassinosteroids	148-163	BRI1-associated receptor kinase	Arabidopsis thaliana	14-19
26528315-3	2015	SERK1, SERK2, SERK3/BAK1, and SERK4/BKK1 have been well characterized to function as crucial regulators in multiple physiological processes such as brassinosteroid signaling, cell death control, pathogenesis, and pollen development.	Brassinosteroids	148-163	BRI1-associated receptor kinase	Arabidopsis thaliana	20-24
26528315-3	2015	SERK1, SERK2, SERK3/BAK1, and SERK4/BKK1 have been well characterized to function as crucial regulators in multiple physiological processes such as brassinosteroid signaling, cell death control, pathogenesis, and pollen development.	Brassinosteroids	148-163	somatic embryogenesis receptor-like kinase 4	Arabidopsis thaliana	30-35
26528315-3	2015	SERK1, SERK2, SERK3/BAK1, and SERK4/BKK1 have been well characterized to function as crucial regulators in multiple physiological processes such as brassinosteroid signaling, cell death control, pathogenesis, and pollen development.	Brassinosteroids	148-163	somatic embryogenesis receptor-like kinase 4	Arabidopsis thaliana	36-40
27251392-5	2015	RLP23 forms a constitutive, ligand-independent complex with the LRR receptor kinase (LRR-RK) SOBIR1 (Suppressor of Brassinosteroid insensitive 1 (BRI1)-associated kinase (BAK1)-interacting receptor kinase 1), and recruits a second LRR-RK, BAK1, into a tripartite complex upon ligand binding.	Brassinosteroids	115-130	receptor like protein 23	Arabidopsis thaliana	0-5
26371323-4	2015	Loss-of-function ebs7 mutations prevent ERAD of brassinosteroid insensitive 1-9 (bri1-9) and bri1-5, two ER-retained mutant variants of the cell-surface receptor for brassinosteroids (BRs).	Brassinosteroids	166-182	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	81-87
26371323-4	2015	Loss-of-function ebs7 mutations prevent ERAD of brassinosteroid insensitive 1-9 (bri1-9) and bri1-5, two ER-retained mutant variants of the cell-surface receptor for brassinosteroids (BRs).	Brassinosteroids	166-182	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	93-99
26371323-5	2015	As a result, the two mutant receptors accumulate in the ER and consequently leak to the plasma membrane, resulting in the restoration of BR sensitivity and phenotypic suppression of the bri1-9 and bri1-5 mutants.	Brassinosteroids	137-139	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	197-203
26233893-1	2015	Our previous studies indicated that TCP1 is a positive regulator of the brassinosteroid (BR) biosynthesis pathway by mediating the transcription of DWF4, one of the key BR biosynthetic genes in Arabidopsis thaliana.	Brassinosteroids	72-87	Cytochrome P450 superfamily protein	Arabidopsis thaliana	148-152
26233893-1	2015	Our previous studies indicated that TCP1 is a positive regulator of the brassinosteroid (BR) biosynthesis pathway by mediating the transcription of DWF4, one of the key BR biosynthetic genes in Arabidopsis thaliana.	Brassinosteroids	89-91	T-complex protein 1 alpha subunit	Arabidopsis thaliana	36-40
26233893-1	2015	Our previous studies indicated that TCP1 is a positive regulator of the brassinosteroid (BR) biosynthesis pathway by mediating the transcription of DWF4, one of the key BR biosynthetic genes in Arabidopsis thaliana.	Brassinosteroids	89-91	Cytochrome P450 superfamily protein	Arabidopsis thaliana	148-152
26233893-1	2015	Our previous studies indicated that TCP1 is a positive regulator of the brassinosteroid (BR) biosynthesis pathway by mediating the transcription of DWF4, one of the key BR biosynthetic genes in Arabidopsis thaliana.	Brassinosteroids	169-171	T-complex protein 1 alpha subunit	Arabidopsis thaliana	36-40
26233893-1	2015	Our previous studies indicated that TCP1 is a positive regulator of the brassinosteroid (BR) biosynthesis pathway by mediating the transcription of DWF4, one of the key BR biosynthetic genes in Arabidopsis thaliana.	Brassinosteroids	169-171	Cytochrome P450 superfamily protein	Arabidopsis thaliana	148-152
25941233-8	2015	It also affected the activities of BR-induced antioxidant defense-related enzymes, namely ascorbate peroxidase (APX), catalase (CAT), glutathione reductase (GR), superoxide dismutase (SOD) and NADPH oxidase.	Brassinosteroids	35-37	ascorbate peroxidase 2	Zea mays	112-115
26034265-8	2015	Glc may interact with BR via a hexokinase1 (HXK1)-mediated pathway to regulate etiolated hypocotyl elongation.	Brassinosteroids	22-24	hexokinase 1	Arabidopsis thaliana	31-42
26034265-8	2015	Glc may interact with BR via a hexokinase1 (HXK1)-mediated pathway to regulate etiolated hypocotyl elongation.	Brassinosteroids	22-24	hexokinase 1	Arabidopsis thaliana	44-48
25415975-0	2014	BRASSINOSTEROID INSENSITIVE2 interacts with ABSCISIC ACID INSENSITIVE5 to mediate the antagonism of brassinosteroids to abscisic acid during seed germination in Arabidopsis.	Brassinosteroids	0-15	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	44-70
26034265-9	2015	Brassinosteroid insensitive1 (BRI1) is epistatic to HXK1, as the Glc insensitive2bri1-6 double mutant displayed severe defects in hypocotyl elongation growth similar to its bri1-6 parent.	Brassinosteroids	0-15	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	30-34
26034265-9	2015	Brassinosteroid insensitive1 (BRI1) is epistatic to HXK1, as the Glc insensitive2bri1-6 double mutant displayed severe defects in hypocotyl elongation growth similar to its bri1-6 parent.	Brassinosteroids	0-15	hexokinase 1	Arabidopsis thaliana	52-56
26034265-9	2015	Brassinosteroid insensitive1 (BRI1) is epistatic to HXK1, as the Glc insensitive2bri1-6 double mutant displayed severe defects in hypocotyl elongation growth similar to its bri1-6 parent.	Brassinosteroids	0-15	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	81-87
25678081-2	2015	In a yeast-two-hybrid (Y2H) screen, we identified a number of novel putative brassinosteroid insensitive 1 (BR1)-associated receptor-like kinase 1 (BAK1) interacting proteins including several proteins related to redox regulation.	Brassinosteroids	77-92	BRI1-associated receptor kinase	Arabidopsis thaliana	148-152
25864910-6	2015	SERK2, for instance, does not function in the brassinosteroid pathway, does not interact with BRI1, but is conserved in its BRI1-interacting domain.	Brassinosteroids	46-61	somatic embryogenesis receptor-like kinase 2	Arabidopsis thaliana	0-5
25864910-9	2015	For instance, the SERK1 or SERK2 extracellular domains are essential for SERK function in male sporogenesis, while the SERK3 extracellular and cytoplasmic domains are essential for SERK3 activity in brassinosteroid and flagellin signaling.	Brassinosteroids	199-214	somatic embryogenesis receptor-like kinase 1	Arabidopsis thaliana	18-23
25864910-9	2015	For instance, the SERK1 or SERK2 extracellular domains are essential for SERK function in male sporogenesis, while the SERK3 extracellular and cytoplasmic domains are essential for SERK3 activity in brassinosteroid and flagellin signaling.	Brassinosteroids	199-214	somatic embryogenesis receptor-like kinase 2	Arabidopsis thaliana	27-32
25864910-9	2015	For instance, the SERK1 or SERK2 extracellular domains are essential for SERK function in male sporogenesis, while the SERK3 extracellular and cytoplasmic domains are essential for SERK3 activity in brassinosteroid and flagellin signaling.	Brassinosteroids	199-214	BRI1-associated receptor kinase	Arabidopsis thaliana	119-124
25864910-9	2015	For instance, the SERK1 or SERK2 extracellular domains are essential for SERK function in male sporogenesis, while the SERK3 extracellular and cytoplasmic domains are essential for SERK3 activity in brassinosteroid and flagellin signaling.	Brassinosteroids	199-214	BRI1-associated receptor kinase	Arabidopsis thaliana	181-186
25778412-6	2015	Furthermore, geldanamycin, an inhibitor of ATPase activity in HSP90, caused BES1 hyperphosphorylation and disrupted the expression of BR-responsive genes.	Brassinosteroids	134-136	heat shock protein 90 alpha family class A member 1	Homo sapiens	62-67
25754244-0	2015	Ethylene mediates brassinosteroid-induced stomatal closure via Galpha protein-activated hydrogen peroxide and nitric oxide production in Arabidopsis.	Brassinosteroids	18-33	succinate-CoA ligase GDP/ADP-forming subunit alpha	Homo sapiens	63-69
25609555-9	2015	BR perception inhibits BIN2 activity, allowing dephosphorylation of BES1 to regulate plant development.	Brassinosteroids	0-2	Protein kinase superfamily protein	Arabidopsis thaliana	23-27
25609555-9	2015	BR perception inhibits BIN2 activity, allowing dephosphorylation of BES1 to regulate plant development.	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	68-72
25649439-0	2015	A recently evolved isoform of the transcription factor BES1 promotes brassinosteroid signaling and development in Arabidopsis thaliana.	Brassinosteroids	69-84	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	55-59
28510978-3	2014	In this study, we have characterized the role of Arabidopsis Qc-SNARE protein AtBS14b in brassinosteroids (BRs) signaling pathway.	Brassinosteroids	89-105	Target SNARE coiled-coil domain protein	Arabidopsis thaliana	78-85
28510978-3	2014	In this study, we have characterized the role of Arabidopsis Qc-SNARE protein AtBS14b in brassinosteroids (BRs) signaling pathway.	Brassinosteroids	107-110	Target SNARE coiled-coil domain protein	Arabidopsis thaliana	78-85
28510978-5	2014	BR biosynthesis enzyme BR6OX2 expression was slightly lower in AtBS14b ox than in wild type plants.	Brassinosteroids	0-2	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	23-29
28510978-5	2014	BR biosynthesis enzyme BR6OX2 expression was slightly lower in AtBS14b ox than in wild type plants.	Brassinosteroids	0-2	Target SNARE coiled-coil domain protein	Arabidopsis thaliana	63-70
28510978-6	2014	Further BR-mediated repression of BR6OX2, CPD and DWF4 was inhibited in AtBS14b ox plants.	Brassinosteroids	8-10	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	34-40
28510978-6	2014	Further BR-mediated repression of BR6OX2, CPD and DWF4 was inhibited in AtBS14b ox plants.	Brassinosteroids	8-10	Cytochrome P450 superfamily protein	Arabidopsis thaliana	50-54
28510978-6	2014	Further BR-mediated repression of BR6OX2, CPD and DWF4 was inhibited in AtBS14b ox plants.	Brassinosteroids	8-10	Target SNARE coiled-coil domain protein	Arabidopsis thaliana	72-79
25647327-0	2015	Calcium and ZmCCaMK are involved in brassinosteroid-induced antioxidant defense in maize leaves.	Brassinosteroids	36-51	putative calcium/calmodulin dependent protein kinase	Zea mays	12-19
25647327-5	2015	Treatment with BR induced increases in gene expression and enzyme activity of ZmCCaMK in maize leaves.	Brassinosteroids	15-17	putative calcium/calmodulin dependent protein kinase	Zea mays	78-85
25647327-6	2015	Transient overexpression and silencing of ZmCCaMK in maize protoplasts demonstrated that ZmCCaMK was required for BR-induced antioxidant defense.	Brassinosteroids	114-116	putative calcium/calmodulin dependent protein kinase	Zea mays	42-49
25647327-6	2015	Transient overexpression and silencing of ZmCCaMK in maize protoplasts demonstrated that ZmCCaMK was required for BR-induced antioxidant defense.	Brassinosteroids	114-116	putative calcium/calmodulin dependent protein kinase	Zea mays	89-96
25647327-9	2015	Furthermore, Ca(2+) was required for BR-induced gene expression and activation of ZmCCaMK, while ZmCCaMK was shown to enhance the BR-induced increase in cytosolic Ca(2+) concentration.	Brassinosteroids	130-132	putative calcium/calmodulin dependent protein kinase	Zea mays	97-104
25866388-5	2015	This BZR1 pattern requires local BR catabolism and auxin synthesis, as well as BR signaling.	Brassinosteroids	33-35	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	5-9
25866388-5	2015	This BZR1 pattern requires local BR catabolism and auxin synthesis, as well as BR signaling.	Brassinosteroids	79-81	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	5-9
25588736-5	2015	In addition, mutations in XLG2 suppressed the seedling lethal and cell death phenotypes of BRASSINOSTEROID INSENSITIVE1-associated receptor kinase1-interacting receptor-like kinase1 mutants in an identical way as reported for Arabidopsis Gb-deficient mutants.	Brassinosteroids	91-106	extra-large GTP-binding protein 2	Arabidopsis thaliana	26-30
26340221-4	2015	Based on these results, we proposed that BZR1 may act as a converging node for crosstalk between BR and sugar signaling in regulating plant growth in darkness.	Brassinosteroids	97-99	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	41-45
25256367-0	2014	Arabidopsis gulliver1/SUPERROOT2-7 identifies a metabolic basis for auxin and brassinosteroid synergy.	Brassinosteroids	78-93	cytochrome P450, family 83, subfamily B, polypeptide 1	Arabidopsis thaliana	22-32
25415975-0	2014	BRASSINOSTEROID INSENSITIVE2 interacts with ABSCISIC ACID INSENSITIVE5 to mediate the antagonism of brassinosteroids to abscisic acid during seed germination in Arabidopsis.	Brassinosteroids	100-116	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	44-70
25077683-5	2014	Expression analyses show that the promoter of one of the key enzymes in BR biosynthesis, CYP90A1/CPD, is highly active in the cells of the reproductive tract that form the pathway for pollen tubes from the stigma to the ovules.	Brassinosteroids	72-74	Cytochrome P450 superfamily protein	Arabidopsis thaliana	89-100
25136063-3	2014	Here, we show that the activity of two homologous brassinosteroid (BR) transcriptional effectors, BRASSINAZOLE RESISTANT1 (BZR1) and BRASSINOSTEROID INSENSITIVE1-ETHYL METHANESULFONATE-SUPPRESSOR1 (BES1)/BZR2, blocks these responses, consequently maintaining normal root development under low phosphate conditions without impacting phosphate homeostasis.	Brassinosteroids	50-65	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	98-121
25136063-3	2014	Here, we show that the activity of two homologous brassinosteroid (BR) transcriptional effectors, BRASSINAZOLE RESISTANT1 (BZR1) and BRASSINOSTEROID INSENSITIVE1-ETHYL METHANESULFONATE-SUPPRESSOR1 (BES1)/BZR2, blocks these responses, consequently maintaining normal root development under low phosphate conditions without impacting phosphate homeostasis.	Brassinosteroids	50-65	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	123-127
25136063-3	2014	Here, we show that the activity of two homologous brassinosteroid (BR) transcriptional effectors, BRASSINAZOLE RESISTANT1 (BZR1) and BRASSINOSTEROID INSENSITIVE1-ETHYL METHANESULFONATE-SUPPRESSOR1 (BES1)/BZR2, blocks these responses, consequently maintaining normal root development under low phosphate conditions without impacting phosphate homeostasis.	Brassinosteroids	50-65	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	198-202
25136063-3	2014	Here, we show that the activity of two homologous brassinosteroid (BR) transcriptional effectors, BRASSINAZOLE RESISTANT1 (BZR1) and BRASSINOSTEROID INSENSITIVE1-ETHYL METHANESULFONATE-SUPPRESSOR1 (BES1)/BZR2, blocks these responses, consequently maintaining normal root development under low phosphate conditions without impacting phosphate homeostasis.	Brassinosteroids	50-65	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	204-208
24719453-4	2014	Glc enhanced BR receptor BRASSINOSTEROID INSENSITIVE1 (BRI1) endocytosis from plasma membrane to early endosomes.	Brassinosteroids	25-40	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	55-59
24899077-3	2014	Both BR and ABA induced increases in RBOH1 gene expression, NADPH oxidase activity, apoplastic H2O2 accumulation, and heat and PQ stress tolerance in wild-type plants.	Brassinosteroids	5-7	NADPH oxidase	Solanum lycopersicum	37-42
25135116-2	2014	The membrane receptor BRI1 is a central player in the brassinosteroid signaling cascade.	Brassinosteroids	54-69	BRI1	Hordeum vulgare	22-26
24838002-2	2014	BRs signal through receptors localized to the plasma membrane and other signaling components to regulate the BES1/BZR1 family of transcription factors, which modulates the expression of thousands of genes.	Brassinosteroids	0-3	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	109-113
24807419-11	2014	We propose that BR signaling is mediated by HSP90 activity and via trafficking of BIN2-HSP90 complexes into the cytoplasm.	Brassinosteroids	16-18	Protein kinase superfamily protein	Arabidopsis thaliana	82-86
24654931-0	2014	The sucrose transporter SlSUT2 from tomato interacts with brassinosteroid functioning and affects arbuscular mycorrhiza formation.	Brassinosteroids	58-73	sucrose transporter-like protein	Solanum lycopersicum	24-30
24386951-8	2014	Further genetic results demonstrated that AGO1 acts downstream of TMM and negatively regulates the SPCH transcripts, but in a brassinosteroid-independent manner.	Brassinosteroids	126-141	Stabilizer of iron transporter SufD / Polynucleotidyl transferase	Arabidopsis thaliana	42-46
24547704-2	2014	In Arabidopsis, the general understanding of BR signaling has been greatly attained by genetic and biochemical approaches that led to the identification of central BR signaling components, from the BRI1 receptor at the plasma membrane to downstream acting BR-regulated BRZ1 and BES1 transcription factors in the nuclei.	Brassinosteroids	45-47	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	278-282
24547704-2	2014	In Arabidopsis, the general understanding of BR signaling has been greatly attained by genetic and biochemical approaches that led to the identification of central BR signaling components, from the BRI1 receptor at the plasma membrane to downstream acting BR-regulated BRZ1 and BES1 transcription factors in the nuclei.	Brassinosteroids	164-166	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	278-282
24920333-0	2014	The Chromatin-Remodeling Factor PICKLE Integrates Brassinosteroid and Gibberellin Signaling during Skotomorphogenic Growth in Arabidopsis.	Brassinosteroids	50-65	chromatin remodeling factor	Arabidopsis thaliana	4-31
24920333-0	2014	The Chromatin-Remodeling Factor PICKLE Integrates Brassinosteroid and Gibberellin Signaling during Skotomorphogenic Growth in Arabidopsis.	Brassinosteroids	50-65	chromatin remodeling factor CHD3 (PICKLE)	Arabidopsis thaliana	32-38
24374469-1	2014	KEY MESSAGE: A closer association of HSP90s with brassinosteroid signaling is suggested by the brassinosteroid-triggered formation of an HSP90-containing macromolecular complex and the direct interaction between HSP90.3 and BES1.	Brassinosteroids	49-64	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	224-228
24732353-0	2014	Overexpression of miR172 suppresses the brassinosteroid signaling defects of bak1 in Arabidopsis.	Brassinosteroids	40-55	MIR172a	Arabidopsis thaliana	18-24
24732353-0	2014	Overexpression of miR172 suppresses the brassinosteroid signaling defects of bak1 in Arabidopsis.	Brassinosteroids	40-55	BRI1-associated receptor kinase	Arabidopsis thaliana	77-81
24732353-6	2014	Taken together with its increased BR sensitivity, these results suggest that miR172 regulates vegetative growth patterns by modulating BR sensitivity as well as by the previously identified developmental phase transition.	Brassinosteroids	34-36	MIR172a	Arabidopsis thaliana	77-83
24732353-6	2014	Taken together with its increased BR sensitivity, these results suggest that miR172 regulates vegetative growth patterns by modulating BR sensitivity as well as by the previously identified developmental phase transition.	Brassinosteroids	135-137	MIR172a	Arabidopsis thaliana	77-83
24620000-10	2014	AtRALF1 also induces two brassinosteroid (BR)-downregulated genes involved in the BR biosynthetic pathway: the cytochrome P450 monooxygenases CONSTITUTIVE PHOTOMORPHISM AND DWARFISM (CPD) and DWARF4 (DWF4).	Brassinosteroids	25-40	rapid alkalinization factor 1	Arabidopsis thaliana	0-7
24620000-10	2014	AtRALF1 also induces two brassinosteroid (BR)-downregulated genes involved in the BR biosynthetic pathway: the cytochrome P450 monooxygenases CONSTITUTIVE PHOTOMORPHISM AND DWARFISM (CPD) and DWARF4 (DWF4).	Brassinosteroids	25-40	Cytochrome P450 superfamily protein	Arabidopsis thaliana	192-198
24620000-10	2014	AtRALF1 also induces two brassinosteroid (BR)-downregulated genes involved in the BR biosynthetic pathway: the cytochrome P450 monooxygenases CONSTITUTIVE PHOTOMORPHISM AND DWARFISM (CPD) and DWARF4 (DWF4).	Brassinosteroids	25-40	Cytochrome P450 superfamily protein	Arabidopsis thaliana	200-204
24620000-10	2014	AtRALF1 also induces two brassinosteroid (BR)-downregulated genes involved in the BR biosynthetic pathway: the cytochrome P450 monooxygenases CONSTITUTIVE PHOTOMORPHISM AND DWARFISM (CPD) and DWARF4 (DWF4).	Brassinosteroids	42-44	rapid alkalinization factor 1	Arabidopsis thaliana	0-7
24620000-10	2014	AtRALF1 also induces two brassinosteroid (BR)-downregulated genes involved in the BR biosynthetic pathway: the cytochrome P450 monooxygenases CONSTITUTIVE PHOTOMORPHISM AND DWARFISM (CPD) and DWARF4 (DWF4).	Brassinosteroids	42-44	Cytochrome P450 superfamily protein	Arabidopsis thaliana	192-198
24620000-10	2014	AtRALF1 also induces two brassinosteroid (BR)-downregulated genes involved in the BR biosynthetic pathway: the cytochrome P450 monooxygenases CONSTITUTIVE PHOTOMORPHISM AND DWARFISM (CPD) and DWARF4 (DWF4).	Brassinosteroids	42-44	Cytochrome P450 superfamily protein	Arabidopsis thaliana	200-204
24467344-4	2014	The 178A roots showed higher TaTRIP1 expression and lower levels of the unphosphorylated form of the brassinosteroid (BR) signaling component BZR1, lower expression of POD genes and reduced POD activity and accumulation of the superoxide anion O2(-) in the root elongation zone compared with the 178B roots.	Brassinosteroids	118-120	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	142-146
25715472-7	2014	In the lower leaves, expansin expression is differentially regulated by brassinosteroids, which inhibit NtEXPA1 and upregulate NtEXPA4.	Brassinosteroids	72-88	expansin-A11-like	Nicotiana tabacum	104-111
25715472-7	2014	In the lower leaves, expansin expression is differentially regulated by brassinosteroids, which inhibit NtEXPA1 and upregulate NtEXPA4.	Brassinosteroids	72-88	expansin-A1-like	Nicotiana tabacum	127-134
24675749-1	2014	The Somatic Embryogenesis Receptor Kinase 3 (SERK3)/Brassinosteroid (BR) Insensitive 1-Associated Kinase 1 (BAK1) is required for pattern-triggered immunity (PTI) in Arabidopsis thaliana and Nicotiana benthamiana.	Brassinosteroids	52-67	BRI1-associated receptor kinase	Arabidopsis thaliana	4-43
24675749-1	2014	The Somatic Embryogenesis Receptor Kinase 3 (SERK3)/Brassinosteroid (BR) Insensitive 1-Associated Kinase 1 (BAK1) is required for pattern-triggered immunity (PTI) in Arabidopsis thaliana and Nicotiana benthamiana.	Brassinosteroids	52-67	BRI1-associated receptor kinase	Arabidopsis thaliana	45-50
24675749-1	2014	The Somatic Embryogenesis Receptor Kinase 3 (SERK3)/Brassinosteroid (BR) Insensitive 1-Associated Kinase 1 (BAK1) is required for pattern-triggered immunity (PTI) in Arabidopsis thaliana and Nicotiana benthamiana.	Brassinosteroids	52-67	BRI1-associated receptor kinase	Arabidopsis thaliana	108-112
24675749-6	2014	Co-silencing SlSERK3A and SlSERK3B resulted in spontaneous necrotic lesions and reduced sensitivity to exogenous BR treatment.	Brassinosteroids	113-115	somatic embryogenesis receptor kinase 3A	Solanum lycopersicum	13-21
24675749-6	2014	Co-silencing SlSERK3A and SlSERK3B resulted in spontaneous necrotic lesions and reduced sensitivity to exogenous BR treatment.	Brassinosteroids	113-115	somatic embryogenesis receptor kinase 3B	Solanum lycopersicum	26-34
24443525-3	2014	Here, we identify the basic helix-loop-helix (bHLH) transcription factor homolog of brassinosteroid enhanced expression2 interacting with IBH1 (HBI1) as a negative regulator of PTI signaling in Arabidopsis (Arabidopsis thaliana).	Brassinosteroids	84-99	ILI1 binding bHLH 1	Arabidopsis thaliana	138-142
24443525-3	2014	Here, we identify the basic helix-loop-helix (bHLH) transcription factor homolog of brassinosteroid enhanced expression2 interacting with IBH1 (HBI1) as a negative regulator of PTI signaling in Arabidopsis (Arabidopsis thaliana).	Brassinosteroids	84-99	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	144-148
24443525-7	2014	Overexpression of the HBI1-related bHLHs brassinosteroid enhanced expression2 (BEE2) and cryptochrome-interacting bHLH (CIB1) partially inhibits immunity, indicating that BEE2 and CIB1 may act redundantly with HBI1.	Brassinosteroids	41-56	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	22-26
24443525-7	2014	Overexpression of the HBI1-related bHLHs brassinosteroid enhanced expression2 (BEE2) and cryptochrome-interacting bHLH (CIB1) partially inhibits immunity, indicating that BEE2 and CIB1 may act redundantly with HBI1.	Brassinosteroids	41-56	BR enhanced expression 2	Arabidopsis thaliana	79-83
24443525-7	2014	Overexpression of the HBI1-related bHLHs brassinosteroid enhanced expression2 (BEE2) and cryptochrome-interacting bHLH (CIB1) partially inhibits immunity, indicating that BEE2 and CIB1 may act redundantly with HBI1.	Brassinosteroids	41-56	BR enhanced expression 2	Arabidopsis thaliana	171-175
24374469-1	2014	KEY MESSAGE: A closer association of HSP90s with brassinosteroid signaling is suggested by the brassinosteroid-triggered formation of an HSP90-containing macromolecular complex and the direct interaction between HSP90.3 and BES1.	Brassinosteroids	95-110	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	224-228
24443525-7	2014	Overexpression of the HBI1-related bHLHs brassinosteroid enhanced expression2 (BEE2) and cryptochrome-interacting bHLH (CIB1) partially inhibits immunity, indicating that BEE2 and CIB1 may act redundantly with HBI1.	Brassinosteroids	41-56	cryptochrome-interacting basic-helix-loop-helix 1	Arabidopsis thaliana	180-184
24443525-7	2014	Overexpression of the HBI1-related bHLHs brassinosteroid enhanced expression2 (BEE2) and cryptochrome-interacting bHLH (CIB1) partially inhibits immunity, indicating that BEE2 and CIB1 may act redundantly with HBI1.	Brassinosteroids	41-56	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	210-214
24443525-12	2014	Hence, HBI1 is a positive regulator of BR-triggered responses, and the negative effect of PTI is likely due to the antagonism between BR and PTI signaling.	Brassinosteroids	39-41	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	7-11
24387668-0	2014	Darkness and gulliver2/phyB mutation decrease the abundance of phosphorylated BZR1 to activate brassinosteroid signaling in Arabidopsis.	Brassinosteroids	95-110	phytochrome B	Arabidopsis thaliana	23-27
24387668-0	2014	Darkness and gulliver2/phyB mutation decrease the abundance of phosphorylated BZR1 to activate brassinosteroid signaling in Arabidopsis.	Brassinosteroids	95-110	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	78-82
25036828-0	2014	BPG3 is a novel chloroplast protein that involves the greening of leaves and related to brassinosteroid signaling.	Brassinosteroids	88-103	DUF399 family protein, putative (DUF399 and DUF3411)	Arabidopsis thaliana	0-4
24587042-0	2014	Elevated levels of MYB30 in the phloem accelerate flowering in Arabidopsis through the regulation of FLOWERING LOCUS T. In Arabidopsis thaliana, the R2R3 MYB-like transcription factor MYB30 is a positive regulator of the pathogen-induced hypersensitive response and of brassinosteroid and abscisic acid signaling.	Brassinosteroids	269-284	myb domain protein 30	Arabidopsis thaliana	19-24
24587042-0	2014	Elevated levels of MYB30 in the phloem accelerate flowering in Arabidopsis through the regulation of FLOWERING LOCUS T. In Arabidopsis thaliana, the R2R3 MYB-like transcription factor MYB30 is a positive regulator of the pathogen-induced hypersensitive response and of brassinosteroid and abscisic acid signaling.	Brassinosteroids	269-284	myb domain protein 30	Arabidopsis thaliana	184-189
24370731-2	2014	In Arabidopsis, the activation of this pathway requires binding of BRs to the receptor kinase BRASSINOSTEROID-INSENSITIVE I (AtBRI1).	Brassinosteroids	94-109	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	125-131
24362628-3	2014	Here, we show that phosphorylation of ARF7 and ARF19 by BRASSINOSTEROID-insensitive2 (BIN2) can also potentiate auxin signalling output during lateral root organogenesis.	Brassinosteroids	56-71	ADP ribosylation factor like GTPase 14	Homo sapiens	38-42
25036120-0	2014	Brassinosteroid-related transcription factor BIL1/BZR1 increases plant resistance to insect feeding.	Brassinosteroids	0-15	SHAGGY-related protein kinase dZeta	Arabidopsis thaliana	45-49
25036120-0	2014	Brassinosteroid-related transcription factor BIL1/BZR1 increases plant resistance to insect feeding.	Brassinosteroids	0-15	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	50-54
24023250-9	2013	A noticeable exception was an increased sensitivity of LR elongation to brassinolide in ahk2 ahk3 mutants indicating antagonistic action of cytokinin and brassinosteroid.	Brassinosteroids	154-169	histidine kinase 3	Arabidopsis thaliana	93-97
25482784-2	2014	We have recently proposed that AtRALF1 negatively regulates root cell elongation and lateral root formation by opposing the effects of brassinosteroid (BR).	Brassinosteroids	135-150	rapid alkalinization factor 1	Arabidopsis thaliana	31-38
24308570-5	2013	Genetic and structural analyses indicated that BAK1 and its homologs play indispensible roles in mediating brassinosteroid (BR) signaling pathway by directly perceiving the ligand BR and activating the receptor of BR, BRI1.	Brassinosteroids	107-122	BCL2 antagonist/killer 1	Homo sapiens	47-51
24019147-0	2013	Identification of BZR1-interacting proteins as potential components of the brassinosteroid signaling pathway in Arabidopsis through tandem affinity purification.	Brassinosteroids	75-90	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	18-22
24019147-3	2013	BZR1 activity is highly controlled by BR through reversible phosphorylation, protein degradation, and nucleocytoplasmic shuttling.	Brassinosteroids	38-40	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	0-4
24164091-0	2014	Transcription factor HAT1 is phosphorylated by BIN2 kinase and mediates brassinosteroid repressed gene expression in Arabidopsis.	Brassinosteroids	72-87	Homeobox-leucine zipper protein 4 (HB-4) / HD-ZIP protein	Arabidopsis thaliana	21-25
24164091-0	2014	Transcription factor HAT1 is phosphorylated by BIN2 kinase and mediates brassinosteroid repressed gene expression in Arabidopsis.	Brassinosteroids	72-87	Protein kinase superfamily protein	Arabidopsis thaliana	47-51
24164091-5	2014	HAT1 and its close homolog HAT3 act redundantly, as the double mutant hat1 hat3 displayed a reduced BR response that is stronger than the single mutants alone.	Brassinosteroids	100-102	Homeobox-leucine zipper protein 4 (HB-4) / HD-ZIP protein	Arabidopsis thaliana	0-4
24164091-5	2014	HAT1 and its close homolog HAT3 act redundantly, as the double mutant hat1 hat3 displayed a reduced BR response that is stronger than the single mutants alone.	Brassinosteroids	100-102	homeobox-leucine zipper protein 3	Arabidopsis thaliana	27-31
24164091-5	2014	HAT1 and its close homolog HAT3 act redundantly, as the double mutant hat1 hat3 displayed a reduced BR response that is stronger than the single mutants alone.	Brassinosteroids	100-102	Homeobox-leucine zipper protein 4 (HB-4) / HD-ZIP protein	Arabidopsis thaliana	70-74
24164091-5	2014	HAT1 and its close homolog HAT3 act redundantly, as the double mutant hat1 hat3 displayed a reduced BR response that is stronger than the single mutants alone.	Brassinosteroids	100-102	homeobox-leucine zipper protein 3	Arabidopsis thaliana	75-79
24072582-2	2013	The main BR-perceiving receptor in Arabidopsis (Arabidopsis thaliana) is BRASSINOSTEROID INSENSITIVE1 (BRI1).	Brassinosteroids	73-88	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	103-107
24019427-5	2013	The PEPR coreceptor BRASSINOSTEROID-INSENSITIVE1 Associated Kinase1 contributes to generation of the Pep-activated Ca(2+) signal and leads to increased defense gene expression and resistance to a virulent bacterial pathogen.	Brassinosteroids	20-35	protein kinase 2A	Arabidopsis thaliana	60-67
24019427-5	2013	The PEPR coreceptor BRASSINOSTEROID-INSENSITIVE1 Associated Kinase1 contributes to generation of the Pep-activated Ca(2+) signal and leads to increased defense gene expression and resistance to a virulent bacterial pathogen.	Brassinosteroids	20-35	RNA-binding KH domain-containing protein	Arabidopsis thaliana	101-104
24019427-7	2013	Nitric oxide and reduced nicotinamide adenine dinucleotide phosphate oxidase-dependent reactive oxygen species generation (due to the function of Respiratory Burst Oxidase Homolog proteins D and F) are also involved downstream from the Ca(2+) signal in the Pep immune defense signal transduction cascade, as is the case with BRASSINOSTEROID-INSENSITIVE1 Associated Kinase1 and CPK5, CPK6, and CPK11.	Brassinosteroids	325-340	RNA-binding KH domain-containing protein	Arabidopsis thaliana	257-260
24019427-7	2013	Nitric oxide and reduced nicotinamide adenine dinucleotide phosphate oxidase-dependent reactive oxygen species generation (due to the function of Respiratory Burst Oxidase Homolog proteins D and F) are also involved downstream from the Ca(2+) signal in the Pep immune defense signal transduction cascade, as is the case with BRASSINOSTEROID-INSENSITIVE1 Associated Kinase1 and CPK5, CPK6, and CPK11.	Brassinosteroids	325-340	protein kinase 2A	Arabidopsis thaliana	365-372
24019427-7	2013	Nitric oxide and reduced nicotinamide adenine dinucleotide phosphate oxidase-dependent reactive oxygen species generation (due to the function of Respiratory Burst Oxidase Homolog proteins D and F) are also involved downstream from the Ca(2+) signal in the Pep immune defense signal transduction cascade, as is the case with BRASSINOSTEROID-INSENSITIVE1 Associated Kinase1 and CPK5, CPK6, and CPK11.	Brassinosteroids	325-340	calmodulin-domain protein kinase 5	Arabidopsis thaliana	377-381
24019427-7	2013	Nitric oxide and reduced nicotinamide adenine dinucleotide phosphate oxidase-dependent reactive oxygen species generation (due to the function of Respiratory Burst Oxidase Homolog proteins D and F) are also involved downstream from the Ca(2+) signal in the Pep immune defense signal transduction cascade, as is the case with BRASSINOSTEROID-INSENSITIVE1 Associated Kinase1 and CPK5, CPK6, and CPK11.	Brassinosteroids	325-340	Calcium-dependent protein kinase family protein	Arabidopsis thaliana	383-387
23852441-5	2013	BR-dependent increases in the expression of some genes (INDOLE-3-ACETIC ACID-INDUCIBLE1 and PHYTOCHROME B ACTIVATION-TAGGED SUPPRESSOR1) were impaired in wild-type plants by a Ca(2+) channel blocker and also in the defense-no-death (dnd1) mutant, which lacks a functional cyclic GMP-activated cell membrane Ca(2+)-conducting channel.	Brassinosteroids	0-2	Cyclic nucleotide-regulated ion channel family protein	Arabidopsis thaliana	233-237
24019427-7	2013	Nitric oxide and reduced nicotinamide adenine dinucleotide phosphate oxidase-dependent reactive oxygen species generation (due to the function of Respiratory Burst Oxidase Homolog proteins D and F) are also involved downstream from the Ca(2+) signal in the Pep immune defense signal transduction cascade, as is the case with BRASSINOSTEROID-INSENSITIVE1 Associated Kinase1 and CPK5, CPK6, and CPK11.	Brassinosteroids	325-340	calcium-dependent protein kinase 2	Arabidopsis thaliana	393-398
23993372-1	2013	Brassinosteroids (BRs) signal through plasma membrane-localized receptor BRI1 and other components including negatively acting BIN2 kinase to regulate BES1/BZR1 family transcription factors, which controls the expression of thousands of genes for various BR responses.	Brassinosteroids	0-16	bridging integrator 2	Homo sapiens	127-131
23993372-1	2013	Brassinosteroids (BRs) signal through plasma membrane-localized receptor BRI1 and other components including negatively acting BIN2 kinase to regulate BES1/BZR1 family transcription factors, which controls the expression of thousands of genes for various BR responses.	Brassinosteroids	18-21	bridging integrator 2	Homo sapiens	127-131
23921992-1	2013	Brassinosteroids (BRs) activate the BRI1 and BAK1/SERK3 membrane receptor complex, which leads to a wide range of changes in gene expression, plant growth and development.	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	36-40
23921992-1	2013	Brassinosteroids (BRs) activate the BRI1 and BAK1/SERK3 membrane receptor complex, which leads to a wide range of changes in gene expression, plant growth and development.	Brassinosteroids	0-16	BRI1-associated receptor kinase	Arabidopsis thaliana	45-49
23921992-1	2013	Brassinosteroids (BRs) activate the BRI1 and BAK1/SERK3 membrane receptor complex, which leads to a wide range of changes in gene expression, plant growth and development.	Brassinosteroids	0-16	BRI1-associated receptor kinase	Arabidopsis thaliana	50-55
23975899-7	2013	Knockdown of the two Arabidopsis AP2A genes or overexpression of a dominant-negative version of the medium AP-2 subunit, AP2M, impaired BRI1 endocytosis and enhanced the brassinosteroid signaling.	Brassinosteroids	170-185	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	107-111
23921992-1	2013	Brassinosteroids (BRs) activate the BRI1 and BAK1/SERK3 membrane receptor complex, which leads to a wide range of changes in gene expression, plant growth and development.	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	36-40
23921992-1	2013	Brassinosteroids (BRs) activate the BRI1 and BAK1/SERK3 membrane receptor complex, which leads to a wide range of changes in gene expression, plant growth and development.	Brassinosteroids	18-21	BRI1-associated receptor kinase	Arabidopsis thaliana	45-49
23921992-1	2013	Brassinosteroids (BRs) activate the BRI1 and BAK1/SERK3 membrane receptor complex, which leads to a wide range of changes in gene expression, plant growth and development.	Brassinosteroids	18-21	BRI1-associated receptor kinase	Arabidopsis thaliana	50-55
23843605-1	2013	Brassinosteroids (BRs) are plant hormones that are perceived at the cell surface by a membrane-bound receptor kinase, BRASSINOSTEROID INSENSITIVE1 (BRI1).	Brassinosteroids	0-16	brassinosteroid LRR receptor kinase	Solanum lycopersicum	148-152
23843605-1	2013	Brassinosteroids (BRs) are plant hormones that are perceived at the cell surface by a membrane-bound receptor kinase, BRASSINOSTEROID INSENSITIVE1 (BRI1).	Brassinosteroids	18-21	brassinosteroid LRR receptor kinase	Solanum lycopersicum	148-152
23843605-1	2013	Brassinosteroids (BRs) are plant hormones that are perceived at the cell surface by a membrane-bound receptor kinase, BRASSINOSTEROID INSENSITIVE1 (BRI1).	Brassinosteroids	118-133	brassinosteroid LRR receptor kinase	Solanum lycopersicum	148-152
23843605-4	2013	As a foundation for understanding the mechanism of BR signaling in tomato (Solanum lycopersicum), we used liquid chromatography-tandem mass spectrometry to identify multiple in vitro phosphorylation sites of the tomato BRI1 and BAK1 cytoplasmic domains.	Brassinosteroids	51-53	brassinosteroid LRR receptor kinase	Solanum lycopersicum	219-223
23814276-7	2013	The results suggest that AGB1 interacts with BIN2, but regulates the BR signalling in a BZR1-independent manner.	Brassinosteroids	69-71	GTP binding protein beta 1	Arabidopsis thaliana	25-29
24494235-7	2013	This lack of hallmark characteristics for BR-inacitivion genes suggests that ATST4a encodes an atypical BR catabolic enzyme.	Brassinosteroids	104-106	sulfotransferase 4A	Arabidopsis thaliana	77-83
23763263-5	2013	Here we report the identification of PAR1-interacting factors, including the brassinosteroid signaling components BR-ENHANCED EXPRESSION (BEE) and BES1-INTERACTING MYC-LIKE (BIM), and characterize their role as networked positive regulators of SAS hypocotyl responses.	Brassinosteroids	77-92	phy rapidly regulated 1	Arabidopsis thaliana	37-41
23937635-9	2013	Our data suggest that topical application of brassinosteroids accelerates wound healing by positively modulating inflammatory and reepithelialization phases of the wound repair process, in part by enhancing Akt signaling in the skin at the edges of the wound and enhancing migration of fibroblasts in the wounded area.	Brassinosteroids	45-61	thymoma viral proto-oncogene 1	Mus musculus	207-210
23814276-0	2013	Arabidopsis heterotrimeric G protein beta subunit, AGB1, regulates brassinosteroid signalling independently of BZR1.	Brassinosteroids	67-82	GTP binding protein beta 1	Arabidopsis thaliana	51-55
23814276-1	2013	The Arabidopsis thaliana heterotrimeric G protein beta subunit, AGB1, is involved in both abscisic acid (ABA) signalling and brassinosteroid (BR) signalling, but it is unclear how AGB1 regulates these signalling pathways.	Brassinosteroids	125-140	GTP binding protein beta 1	Arabidopsis thaliana	64-68
23814276-1	2013	The Arabidopsis thaliana heterotrimeric G protein beta subunit, AGB1, is involved in both abscisic acid (ABA) signalling and brassinosteroid (BR) signalling, but it is unclear how AGB1 regulates these signalling pathways.	Brassinosteroids	142-144	GTP binding protein beta 1	Arabidopsis thaliana	64-68
23814276-4	2013	Expression of bzr1-1 alleviated the effects of a BR biosynthesis inhibitor, brassinazole, in both the wild type and agb1-1, and overexpression of BZR1 alleviated the effects of ABA in both the wild type and agb1-1.	Brassinosteroids	49-51	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	14-18
23796795-4	2013	Recently, it was shown that the initiation of BR signal transduction requires the interaction of BRI1 with its SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE (SERK) coreceptors.	Brassinosteroids	46-48	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	97-101
23733062-8	2013	Previously, it was shown that BSK1 is a substrate of the brassinosteroid (BR) receptor BRI1 (brassinosteroid insensitive 1) and plays critical roles in BR signaling.	Brassinosteroids	57-72	BR-signaling kinase 1	Arabidopsis thaliana	30-34
23733062-8	2013	Previously, it was shown that BSK1 is a substrate of the brassinosteroid (BR) receptor BRI1 (brassinosteroid insensitive 1) and plays critical roles in BR signaling.	Brassinosteroids	57-72	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	87-91
23771896-6	2013	BR activates expression of SHORT HYPOCOTYL UNDER BLUE1, MINISEED3, and HAIKU2, which are known positive regulators of seed size, but represses APETALA2 and AUXIN RESPONSE FACTOR2, which are negative regulators of seed size.	Brassinosteroids	0-2	WRKY DNA-binding protein 10	Arabidopsis thaliana	56-65
23771896-6	2013	BR activates expression of SHORT HYPOCOTYL UNDER BLUE1, MINISEED3, and HAIKU2, which are known positive regulators of seed size, but represses APETALA2 and AUXIN RESPONSE FACTOR2, which are negative regulators of seed size.	Brassinosteroids	0-2	Leucine-rich repeat protein kinase family protein	Arabidopsis thaliana	71-77
23771896-6	2013	BR activates expression of SHORT HYPOCOTYL UNDER BLUE1, MINISEED3, and HAIKU2, which are known positive regulators of seed size, but represses APETALA2 and AUXIN RESPONSE FACTOR2, which are negative regulators of seed size.	Brassinosteroids	0-2	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	143-151
23796795-0	2013	Visualization of BRI1 and BAK1(SERK3) membrane receptor heterooligomers during brassinosteroid signaling.	Brassinosteroids	79-94	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	17-21
23796795-0	2013	Visualization of BRI1 and BAK1(SERK3) membrane receptor heterooligomers during brassinosteroid signaling.	Brassinosteroids	79-94	BRI1-associated receptor kinase	Arabidopsis thaliana	26-30
23796795-0	2013	Visualization of BRI1 and BAK1(SERK3) membrane receptor heterooligomers during brassinosteroid signaling.	Brassinosteroids	79-94	BRI1-associated receptor kinase	Arabidopsis thaliana	31-36
23796795-1	2013	The leucine-rich repeat receptor-like kinase BRASSINOSTEROID-INSENSITIVE1 (BRI1) is the main ligand-perceiving receptor for brassinosteroids (BRs) in Arabidopsis (Arabidopsis thaliana).	Brassinosteroids	124-140	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	75-79
23796795-7	2013	We show that activation of BR signaling by exogenous ligand application resulted in both elevated colocalization between BRI1 and BAK1(SERK3) and an about 50% increase of receptor heterooligomerization in the PM of live Arabidopsis root epidermal cells.	Brassinosteroids	27-29	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	121-125
23796795-7	2013	We show that activation of BR signaling by exogenous ligand application resulted in both elevated colocalization between BRI1 and BAK1(SERK3) and an about 50% increase of receptor heterooligomerization in the PM of live Arabidopsis root epidermal cells.	Brassinosteroids	27-29	BRI1-associated receptor kinase	Arabidopsis thaliana	130-134
23796795-7	2013	We show that activation of BR signaling by exogenous ligand application resulted in both elevated colocalization between BRI1 and BAK1(SERK3) and an about 50% increase of receptor heterooligomerization in the PM of live Arabidopsis root epidermal cells.	Brassinosteroids	27-29	BRI1-associated receptor kinase	Arabidopsis thaliana	135-140
23125315-0	2013	Brassinosteroids regulate the differential growth of Arabidopsis hypocotyls through auxin signaling components IAA19 and ARF7.	Brassinosteroids	0-16	indole-3-acetic acid inducible 19	Arabidopsis thaliana	111-116
23897924-5	2013	Electrophoretic mobility shift assay and chromatin immunoprecipitation revealed that BZR1 bound to a putative BR response cis-element and suppressed the expression of FLD.	Brassinosteroids	110-112	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	85-89
23494613-0	2013	A novel mitochondrial DnaJ/Hsp40 family protein BIL2 promotes plant growth and resistance against environmental stress in brassinosteroid signaling.	Brassinosteroids	122-137	DnaJ heat shock protein family (Hsp40) member B6	Homo sapiens	22-26
23496207-2	2013	Previous analysis demonstrated a positive role for BSK1 and BSK3 in the initial steps of brassinosteroid (BR) signal transduction.	Brassinosteroids	89-104	BR-signaling kinase 1	Arabidopsis thaliana	51-55
23496207-2	2013	Previous analysis demonstrated a positive role for BSK1 and BSK3 in the initial steps of brassinosteroid (BR) signal transduction.	Brassinosteroids	89-104	BR-signaling kinase 3	Arabidopsis thaliana	60-64
23818580-0	2013	Inverse modulation of plant immune and brassinosteroid signaling pathways by the receptor-like cytoplasmic kinase BIK1.	Brassinosteroids	39-54	botrytis-induced kinase1	Arabidopsis thaliana	114-118
23818580-4	2013	BR homeostasis and signaling unidirectionally modulate FLS2-mediated immune responses at multiple levels.	Brassinosteroids	0-2	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	55-59
23818580-7	2013	The bik1 mutant displays various BR hypersensitive phenotypes accompanied with increased accumulation of de-phosphorylated BES1 proteins and transcriptional regulation of BZR1 and BES1 target genes.	Brassinosteroids	33-35	botrytis-induced kinase1	Arabidopsis thaliana	4-8
23818580-12	2013	Thus, BIK1 relays the signaling in plant immunity and BR-mediated growth via distinct phosphorylation by BAK1 and BRI1, respectively.	Brassinosteroids	54-56	botrytis-induced kinase1	Arabidopsis thaliana	6-10
23818580-12	2013	Thus, BIK1 relays the signaling in plant immunity and BR-mediated growth via distinct phosphorylation by BAK1 and BRI1, respectively.	Brassinosteroids	54-56	BRI1-associated receptor kinase	Arabidopsis thaliana	105-109
23818580-12	2013	Thus, BIK1 relays the signaling in plant immunity and BR-mediated growth via distinct phosphorylation by BAK1 and BRI1, respectively.	Brassinosteroids	54-56	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	114-118
23297052-0	2013	Arabidopsis brassinosteroid-overproducing gulliver3-D/dwarf4-D mutants exhibit altered responses to jasmonic acid and pathogen.	Brassinosteroids	12-27	Cytochrome P450 superfamily protein	Arabidopsis thaliana	54-60
23297052-1	2013	KEY MESSAGE : Arabidopsis gulliver3 - D/dwarf4 - D displays growth-promoting phenotypes due to activation tagging of a key brassinosteroid biosynthetic gene DWARF4.	Brassinosteroids	123-138	Cytochrome P450 superfamily protein	Arabidopsis thaliana	40-46
23297052-1	2013	KEY MESSAGE : Arabidopsis gulliver3 - D/dwarf4 - D displays growth-promoting phenotypes due to activation tagging of a key brassinosteroid biosynthetic gene DWARF4.	Brassinosteroids	123-138	Cytochrome P450 superfamily protein	Arabidopsis thaliana	157-163
23297052-4	2013	Brassinosteroids (BRs), steroidal hormones essential for plant growth, are regulated by other plant hormones, including auxin and jasmonates (JA); auxin stimulates the expression of a key brassinosteroid (BR) biosynthetic gene, DWARF4 (DWF4), whereas JA represses it.	Brassinosteroids	0-16	Cytochrome P450 superfamily protein	Arabidopsis thaliana	228-234
23297052-4	2013	Brassinosteroids (BRs), steroidal hormones essential for plant growth, are regulated by other plant hormones, including auxin and jasmonates (JA); auxin stimulates the expression of a key brassinosteroid (BR) biosynthetic gene, DWARF4 (DWF4), whereas JA represses it.	Brassinosteroids	0-16	Cytochrome P450 superfamily protein	Arabidopsis thaliana	236-240
23580754-0	2013	BZR1 and BES1 participate in regulation of glucosinolate biosynthesis by brassinosteroids in Arabidopsis.	Brassinosteroids	73-89	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	0-4
23125315-0	2013	Brassinosteroids regulate the differential growth of Arabidopsis hypocotyls through auxin signaling components IAA19 and ARF7.	Brassinosteroids	0-16	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	121-125
23580754-0	2013	BZR1 and BES1 participate in regulation of glucosinolate biosynthesis by brassinosteroids in Arabidopsis.	Brassinosteroids	73-89	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	9-13
23580754-3	2013	In addition, a significantly higher level of glucosinolates accumulated in the BR-deficient mutant cpd and a dramatically lower glucosinolate content in the transgenic plant DWF4-ox overexpressing the BR biosynthetic gene DWF4 compared with their related wild-types, confirmed the repressing effect of BR on glucosinolate biosynthesis.	Brassinosteroids	201-203	Cytochrome P450 superfamily protein	Arabidopsis thaliana	174-178
23580754-3	2013	In addition, a significantly higher level of glucosinolates accumulated in the BR-deficient mutant cpd and a dramatically lower glucosinolate content in the transgenic plant DWF4-ox overexpressing the BR biosynthetic gene DWF4 compared with their related wild-types, confirmed the repressing effect of BR on glucosinolate biosynthesis.	Brassinosteroids	201-203	Cytochrome P450 superfamily protein	Arabidopsis thaliana	222-226
23580754-5	2013	Furthermore, the observation of reduced content of glucosinolates and lower expression levels of glucosinolate biosynthetic genes in 35S-BZR1/bzr1-1D and bes1-D plants compared with the corresponding wild-types suggested that BZR1 and BES1, two important components in BR signal transduction, are responsible for the inhibiting role of BR in glucosinolate biosynthesis.	Brassinosteroids	269-271	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	142-146
23580754-5	2013	Furthermore, the observation of reduced content of glucosinolates and lower expression levels of glucosinolate biosynthetic genes in 35S-BZR1/bzr1-1D and bes1-D plants compared with the corresponding wild-types suggested that BZR1 and BES1, two important components in BR signal transduction, are responsible for the inhibiting role of BR in glucosinolate biosynthesis.	Brassinosteroids	269-271	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	154-158
23580754-5	2013	Furthermore, the observation of reduced content of glucosinolates and lower expression levels of glucosinolate biosynthetic genes in 35S-BZR1/bzr1-1D and bes1-D plants compared with the corresponding wild-types suggested that BZR1 and BES1, two important components in BR signal transduction, are responsible for the inhibiting role of BR in glucosinolate biosynthesis.	Brassinosteroids	269-271	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	226-230
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	31-33	indole-3-acetic acid inducible 19	Arabidopsis thaliana	200-204
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	31-33	indole-3-acetic acid inducible 19	Arabidopsis thaliana	225-230
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	31-33	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	236-240
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	31-33	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	319-323
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	31-33	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	346-350
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	indole-3-acetic acid inducible 19	Arabidopsis thaliana	225-230
23580754-5	2013	Furthermore, the observation of reduced content of glucosinolates and lower expression levels of glucosinolate biosynthetic genes in 35S-BZR1/bzr1-1D and bes1-D plants compared with the corresponding wild-types suggested that BZR1 and BES1, two important components in BR signal transduction, are responsible for the inhibiting role of BR in glucosinolate biosynthesis.	Brassinosteroids	336-338	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	142-146
23580754-5	2013	Furthermore, the observation of reduced content of glucosinolates and lower expression levels of glucosinolate biosynthetic genes in 35S-BZR1/bzr1-1D and bes1-D plants compared with the corresponding wild-types suggested that BZR1 and BES1, two important components in BR signal transduction, are responsible for the inhibiting role of BR in glucosinolate biosynthesis.	Brassinosteroids	336-338	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	154-158
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	236-240
23580754-5	2013	Furthermore, the observation of reduced content of glucosinolates and lower expression levels of glucosinolate biosynthetic genes in 35S-BZR1/bzr1-1D and bes1-D plants compared with the corresponding wild-types suggested that BZR1 and BES1, two important components in BR signal transduction, are responsible for the inhibiting role of BR in glucosinolate biosynthesis.	Brassinosteroids	336-338	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	226-230
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	319-323
23580754-6	2013	The disappearance of the repressing effect of BR on glucosinolate content in the myb28, myb34, and myb122 mutants indicated that these three MYB factors are important for the regulation of BR in glucosinolate biosynthesis.	Brassinosteroids	46-48	myb domain protein 28	Arabidopsis thaliana	81-86
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	346-350
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	indole-3-acetic acid inducible 19	Arabidopsis thaliana	225-230
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	236-240
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	319-323
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	346-350
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	indole-3-acetic acid inducible 19	Arabidopsis thaliana	225-230
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	236-240
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	319-323
23125315-3	2013	Here, we demonstrate that high BR concentration or enhanced BR signaling induce the differential growth of etiolated hypocotyls and result in the morphological changes, while auxin-resistant mutants, msg2 (dominant mutant of IAA19) and arf7, are insensitive to the BR effect and can partially suppress the phenotype of bzr1-D (dominant mutant of BZR1 with enhanced BR signaling).	Brassinosteroids	60-62	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	346-350
23125315-5	2013	Systemic microarray analysis revealed that a number of BR-responsive genes showed reduced BR response in msg2, confirming that BR employs auxin signaling components IAA19 and ARF7 to modulate the specific downstream processes.	Brassinosteroids	55-57	indole-3-acetic acid inducible 19	Arabidopsis thaliana	105-109
23125315-5	2013	Systemic microarray analysis revealed that a number of BR-responsive genes showed reduced BR response in msg2, confirming that BR employs auxin signaling components IAA19 and ARF7 to modulate the specific downstream processes.	Brassinosteroids	55-57	indole-3-acetic acid inducible 19	Arabidopsis thaliana	165-170
23125315-5	2013	Systemic microarray analysis revealed that a number of BR-responsive genes showed reduced BR response in msg2, confirming that BR employs auxin signaling components IAA19 and ARF7 to modulate the specific downstream processes.	Brassinosteroids	55-57	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	175-179
23125315-5	2013	Systemic microarray analysis revealed that a number of BR-responsive genes showed reduced BR response in msg2, confirming that BR employs auxin signaling components IAA19 and ARF7 to modulate the specific downstream processes.	Brassinosteroids	90-92	indole-3-acetic acid inducible 19	Arabidopsis thaliana	105-109
23125315-5	2013	Systemic microarray analysis revealed that a number of BR-responsive genes showed reduced BR response in msg2, confirming that BR employs auxin signaling components IAA19 and ARF7 to modulate the specific downstream processes.	Brassinosteroids	90-92	indole-3-acetic acid inducible 19	Arabidopsis thaliana	165-170
23125315-5	2013	Systemic microarray analysis revealed that a number of BR-responsive genes showed reduced BR response in msg2, confirming that BR employs auxin signaling components IAA19 and ARF7 to modulate the specific downstream processes.	Brassinosteroids	90-92	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	175-179
22994632-0	2013	Silencing of tomato RBOH1 and MPK2 abolishes brassinosteroid-induced H2O2 generation and stress tolerance.	Brassinosteroids	45-60	NADPH oxidase	Solanum lycopersicum	20-25
23514038-3	2013	Brz2001 is a brassinosteroid biosynthesis inhibitor in the less-soluble triazole series of compounds that targets DWARF4, a cytochrome P450 (Cyp450) monooxygenase containing heme and iron.	Brassinosteroids	13-28	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	124-139
23514038-3	2013	Brz2001 is a brassinosteroid biosynthesis inhibitor in the less-soluble triazole series of compounds that targets DWARF4, a cytochrome P450 (Cyp450) monooxygenase containing heme and iron.	Brassinosteroids	13-28	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	141-147
23398263-6	2013	We found that the male-sterility phenotype caused by the Atpub4 mutation is temperature-dependent: the mutant plants are sterile when grown at 22 C but are partially fertile at 16 C. Our study also indicates that the AtPUB4-mediated pathway acts in parallel with the brassinosteroid pathway in controlling developmental fates of the tapetal cells to ensure male fertility.	Brassinosteroids	267-282	RING/U-box superfamily protein with ARM repeat domain-containing protein	Arabidopsis thaliana	57-63
23398263-6	2013	We found that the male-sterility phenotype caused by the Atpub4 mutation is temperature-dependent: the mutant plants are sterile when grown at 22 C but are partially fertile at 16 C. Our study also indicates that the AtPUB4-mediated pathway acts in parallel with the brassinosteroid pathway in controlling developmental fates of the tapetal cells to ensure male fertility.	Brassinosteroids	267-282	RING/U-box superfamily protein with ARM repeat domain-containing protein	Arabidopsis thaliana	217-223
22994632-0	2013	Silencing of tomato RBOH1 and MPK2 abolishes brassinosteroid-induced H2O2 generation and stress tolerance.	Brassinosteroids	45-60	mitogen-activated protein kinase 2	Solanum lycopersicum	30-34
22994632-7	2013	BR-induced tolerance and MPK1/2 activation were compromised in RBOH1-, MPK2- and MPK1/2-silenced plants but not in MPK1-silenced plants.	Brassinosteroids	0-2	NADPH oxidase	Solanum lycopersicum	63-68
22994632-7	2013	BR-induced tolerance and MPK1/2 activation were compromised in RBOH1-, MPK2- and MPK1/2-silenced plants but not in MPK1-silenced plants.	Brassinosteroids	0-2	mitogen-activated protein kinase 2	Solanum lycopersicum	71-75
22994632-7	2013	BR-induced tolerance and MPK1/2 activation were compromised in RBOH1-, MPK2- and MPK1/2-silenced plants but not in MPK1-silenced plants.	Brassinosteroids	0-2	Mitogen-activated protein kinase	Solanum lycopersicum	81-85
22994632-7	2013	BR-induced tolerance and MPK1/2 activation were compromised in RBOH1-, MPK2- and MPK1/2-silenced plants but not in MPK1-silenced plants.	Brassinosteroids	0-2	Mitogen-activated protein kinase	Solanum lycopersicum	81-85
22914576-0	2013	BR signal influences Arabidopsis ovule and seed number through regulating related genes expression by BZR1.	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	102-106
23083315-10	2013	Quantitative PCR analysis of BR-related genes in wild-type, pskr1-3 pskr2-1, PSKR1ox and tpst-1 seedlings showed largely unchanged transcript levels of BR biosynthesis genes.	Brassinosteroids	29-31	phytosulfokin receptor 1	Arabidopsis thaliana	77-82
23204503-0	2013	Homeostasis of brassinosteroids regulated by DRL1, a putative acyltransferase in Arabidopsis.	Brassinosteroids	15-31	KTI12-like, chromatin associated protein	Arabidopsis thaliana	45-49
23204503-2	2013	Here, we identified a dominant mutant, dwarf and round leaf-1 (drl1-D), which exhibits weak BR-deficient or BR-insensitive mutant phenotypes, including short and round leaves, prolonged senescence, dwarfed shape, and altered expression levels of the BR-responsive genes.	Brassinosteroids	92-94	KTI12-like, chromatin associated protein	Arabidopsis thaliana	63-67
22525267-6	2012	Although BR signaling pathway is completely disrupted in the serk1 bak1 bkk1 triple mutant, the root growth of the triple mutant is much severely damaged than the BR deficiency or signaling null mutants.	Brassinosteroids	9-11	somatic embryogenesis receptor-like kinase 1	Arabidopsis thaliana	61-66
23020607-0	2013	BAT1, a putative acyltransferase, modulates brassinosteroid levels in Arabidopsis.	Brassinosteroids	44-59	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	0-4
23020607-4	2013	Over-expression of BAT1 resulted in typical BR-deficient phenotypes, which were rescued by exogenously applied castasterone and brassinolide.	Brassinosteroids	44-46	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	19-23
23020607-5	2013	Analyses of BR profiles demonstrated that BAT1 alters levels of several brassinolide biosynthetic intermediates, including 6-deoxotyphasterol, typhasterol and 6-deoxocastasterone.	Brassinosteroids	12-14	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	42-46
23335967-0	2013	Genetic variation in plant CYP51s confers resistance against voriconazole, a novel inhibitor of brassinosteroid-dependent sterol biosynthesis.	Brassinosteroids	96-111	cytochrome P450 family 51 subfamily A member 1	Homo sapiens	27-32
23335967-6	2013	We uncover that voriconazole toxicity in plants is a result of a deficiency in BRs that stems from an inhibition of the cytochrome P450 CYP51, which catalyzes a step of BR-dependent sterol biosynthesis.	Brassinosteroids	79-81	cytochrome P450 family 51 subfamily A member 1	Homo sapiens	136-141
23213252-9	2012	In addition, LOB expression is BR regulated; therefore, LOB and BR form a feedback loop to modulate local BR accumulation in organ boundaries to limit growth in the boundary domain.	Brassinosteroids	31-33	Lateral organ boundaries (LOB) domain family protein	Arabidopsis thaliana	13-16
23213252-9	2012	In addition, LOB expression is BR regulated; therefore, LOB and BR form a feedback loop to modulate local BR accumulation in organ boundaries to limit growth in the boundary domain.	Brassinosteroids	31-33	Lateral organ boundaries (LOB) domain family protein	Arabidopsis thaliana	56-59
23037003-7	2012	They include not only auxin-associated genes (GH3.5, IAA19 and IAA29), but also genes associated with other growth-regulating hormones such as brassinosteroids (BR6ox2), gibberellic acids (GAI), ethylene (ACS8) and cytokinin (CKX5).	Brassinosteroids	143-159	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	161-167
22956280-8	2012	Genome-wide transcriptome profiling of abs1-1D revealed clear reprogramming of metabolic pathways, and it was demonstrated that BR biosynthesis genes were activated in abs1-1D and that the flavonoid biosynthesis pathway was repressed in abs1-1D, as well as in det2-1.	Brassinosteroids	128-130	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	168-172
22956280-8	2012	Genome-wide transcriptome profiling of abs1-1D revealed clear reprogramming of metabolic pathways, and it was demonstrated that BR biosynthesis genes were activated in abs1-1D and that the flavonoid biosynthesis pathway was repressed in abs1-1D, as well as in det2-1.	Brassinosteroids	128-130	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	168-172
23115248-10	2012	This study reveals a mechanism involving BR regulation of microtubules through MDP40 to mediate hypocotyl cell elongation.	Brassinosteroids	41-43	hypothetical protein	Arabidopsis thaliana	79-84
22516478-5	2012	A T-DNA insertional atos9-t mutation blocks the degradation of a structurally imperfect yet biochemically competent brassinosteroid (BR) receptor bri1-9, causing its increased accumulation in the ER and its consequent leakage to the cell surface responsible for restoring the BR sensitivity and suppressing the dwarfism of the bri1-9 mutant.	Brassinosteroids	116-131	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	146-152
22516478-5	2012	A T-DNA insertional atos9-t mutation blocks the degradation of a structurally imperfect yet biochemically competent brassinosteroid (BR) receptor bri1-9, causing its increased accumulation in the ER and its consequent leakage to the cell surface responsible for restoring the BR sensitivity and suppressing the dwarfism of the bri1-9 mutant.	Brassinosteroids	116-131	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	327-333
22516478-5	2012	A T-DNA insertional atos9-t mutation blocks the degradation of a structurally imperfect yet biochemically competent brassinosteroid (BR) receptor bri1-9, causing its increased accumulation in the ER and its consequent leakage to the cell surface responsible for restoring the BR sensitivity and suppressing the dwarfism of the bri1-9 mutant.	Brassinosteroids	133-135	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	146-152
22516478-5	2012	A T-DNA insertional atos9-t mutation blocks the degradation of a structurally imperfect yet biochemically competent brassinosteroid (BR) receptor bri1-9, causing its increased accumulation in the ER and its consequent leakage to the cell surface responsible for restoring the BR sensitivity and suppressing the dwarfism of the bri1-9 mutant.	Brassinosteroids	133-135	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	327-333
23083315-9	2013	Inhibition of brassinosteroid (BR) biosynthesis with brassinazole (BZ) caused a loss of responsiveness to PSK in wild-type, tpst-1 (tyrosylprotein sulfotransferase-1), PSKR1ox12 and CER6:PSKR1-3-1 seedlings, as did the genetic knock-out of BR synthesis in det2-1 and of BR perception in bri1-9, suggesting that BR mediates PSK-dependent growth.	Brassinosteroids	14-29	3-ketoacyl-CoA synthase 6	Arabidopsis thaliana	182-186
23083315-9	2013	Inhibition of brassinosteroid (BR) biosynthesis with brassinazole (BZ) caused a loss of responsiveness to PSK in wild-type, tpst-1 (tyrosylprotein sulfotransferase-1), PSKR1ox12 and CER6:PSKR1-3-1 seedlings, as did the genetic knock-out of BR synthesis in det2-1 and of BR perception in bri1-9, suggesting that BR mediates PSK-dependent growth.	Brassinosteroids	14-29	phytosulfokin receptor 1	Arabidopsis thaliana	168-173
23083315-9	2013	Inhibition of brassinosteroid (BR) biosynthesis with brassinazole (BZ) caused a loss of responsiveness to PSK in wild-type, tpst-1 (tyrosylprotein sulfotransferase-1), PSKR1ox12 and CER6:PSKR1-3-1 seedlings, as did the genetic knock-out of BR synthesis in det2-1 and of BR perception in bri1-9, suggesting that BR mediates PSK-dependent growth.	Brassinosteroids	14-29	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	287-293
23083315-9	2013	Inhibition of brassinosteroid (BR) biosynthesis with brassinazole (BZ) caused a loss of responsiveness to PSK in wild-type, tpst-1 (tyrosylprotein sulfotransferase-1), PSKR1ox12 and CER6:PSKR1-3-1 seedlings, as did the genetic knock-out of BR synthesis in det2-1 and of BR perception in bri1-9, suggesting that BR mediates PSK-dependent growth.	Brassinosteroids	31-33	3-ketoacyl-CoA synthase 6	Arabidopsis thaliana	182-186
23083315-9	2013	Inhibition of brassinosteroid (BR) biosynthesis with brassinazole (BZ) caused a loss of responsiveness to PSK in wild-type, tpst-1 (tyrosylprotein sulfotransferase-1), PSKR1ox12 and CER6:PSKR1-3-1 seedlings, as did the genetic knock-out of BR synthesis in det2-1 and of BR perception in bri1-9, suggesting that BR mediates PSK-dependent growth.	Brassinosteroids	31-33	phytosulfokin receptor 1	Arabidopsis thaliana	168-173
23083315-9	2013	Inhibition of brassinosteroid (BR) biosynthesis with brassinazole (BZ) caused a loss of responsiveness to PSK in wild-type, tpst-1 (tyrosylprotein sulfotransferase-1), PSKR1ox12 and CER6:PSKR1-3-1 seedlings, as did the genetic knock-out of BR synthesis in det2-1 and of BR perception in bri1-9, suggesting that BR mediates PSK-dependent growth.	Brassinosteroids	31-33	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	287-293
23083315-10	2013	Quantitative PCR analysis of BR-related genes in wild-type, pskr1-3 pskr2-1, PSKR1ox and tpst-1 seedlings showed largely unchanged transcript levels of BR biosynthesis genes.	Brassinosteroids	29-31	phytosulfokin receptor 1	Arabidopsis thaliana	60-65
23264517-3	2013	ROTUNDIFOLIA3/CYP90C1 encodes an enzyme which was shown to catalyse C-23 hydroxylation of several brassinosteroids (BRs) - phytohormones involved in, for example, organ growth, cell expansion, cell division, and responses to abiotic and biotic stresses.	Brassinosteroids	98-114	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-13
23264517-3	2013	ROTUNDIFOLIA3/CYP90C1 encodes an enzyme which was shown to catalyse C-23 hydroxylation of several brassinosteroids (BRs) - phytohormones involved in, for example, organ growth, cell expansion, cell division, and responses to abiotic and biotic stresses.	Brassinosteroids	98-114	Cytochrome P450 superfamily protein	Arabidopsis thaliana	14-21
23264517-3	2013	ROTUNDIFOLIA3/CYP90C1 encodes an enzyme which was shown to catalyse C-23 hydroxylation of several brassinosteroids (BRs) - phytohormones involved in, for example, organ growth, cell expansion, cell division, and responses to abiotic and biotic stresses.	Brassinosteroids	116-119	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-13
23264517-3	2013	ROTUNDIFOLIA3/CYP90C1 encodes an enzyme which was shown to catalyse C-23 hydroxylation of several brassinosteroids (BRs) - phytohormones involved in, for example, organ growth, cell expansion, cell division, and responses to abiotic and biotic stresses.	Brassinosteroids	116-119	Cytochrome P450 superfamily protein	Arabidopsis thaliana	14-21
23264517-9	2013	Together, the results show that ROT3 modulates ethylene-induced petiole movement and that this function is likely BR related.	Brassinosteroids	114-116	Cytochrome P450 superfamily protein	Arabidopsis thaliana	32-36
23169658-0	2012	MYBL2 is a substrate of GSK3-like kinase BIN2 and acts as a corepressor of BES1 in brassinosteroid signaling pathway in Arabidopsis.	Brassinosteroids	83-98	MYB-like 2	Arabidopsis thaliana	0-5
23169658-0	2012	MYBL2 is a substrate of GSK3-like kinase BIN2 and acts as a corepressor of BES1 in brassinosteroid signaling pathway in Arabidopsis.	Brassinosteroids	83-98	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	75-79
23169658-6	2012	The loss-of-function mybl2 mutant enhances the phenotype of a weak allele of bri1 and suppresses the constitutive BR-response phenotype of bes1-D.	Brassinosteroids	114-116	MYB-like 2	Arabidopsis thaliana	21-26
23169658-6	2012	The loss-of-function mybl2 mutant enhances the phenotype of a weak allele of bri1 and suppresses the constitutive BR-response phenotype of bes1-D.	Brassinosteroids	114-116	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	139-143
23073004-2	2012	New data show that LEC1, partially in conjunction with abscisic acid, affects auxin synthesis, and both brassinosteroid and light signaling.	Brassinosteroids	104-119	Histone superfamily protein	Arabidopsis thaliana	19-23
23022359-1	2012	Two recent reports show that brassinosteroids control stomata production by regulating the GSK3-like kinase BIN2-mediated phosphorylation of two different stomatal signalling components resulting in opposite stomatal phenotypes.	Brassinosteroids	29-45	bridging integrator 2	Homo sapiens	108-112
22961663-0	2012	Constitutive activation of brassinosteroid signaling in the Arabidopsis elongated-D/bak1 mutant.	Brassinosteroids	27-42	BRI1-associated receptor kinase	Arabidopsis thaliana	84-88
22982312-4	2012	BSK5 transcripts were detected in various tissues, and were induced by abiotic stresses including salt and drought, as well as phytohormones of BR and abscisic acid (ABA).	Brassinosteroids	144-146	kinase with tetratricopeptide repeat domain-containing protein	Arabidopsis thaliana	0-4
23033541-0	2012	An interaction between BZR1 and DELLAs mediates direct signaling crosstalk between brassinosteroids and gibberellins in Arabidopsis.	Brassinosteroids	83-99	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	23-27
22960180-2	2012	Here, we provide evidence that an increase in the BR level increased the quantum yield of PSII, activities of Rubisco activase (RCA) and fructose-1,6-bisphosphatase (FBPase), and CO(2) assimilation.	Brassinosteroids	50-52	ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic	Cucumis sativus	110-126
22822057-0	2012	CYP90A1/CPD, a brassinosteroid biosynthetic cytochrome P450 of Arabidopsis, catalyzes C-3 oxidation.	Brassinosteroids	15-30	Cytochrome P450 superfamily protein	Arabidopsis thaliana	0-11
22822057-6	2012	Enzyme kinetic data of CYP90A1/CPD and DET2, together with those of the earlier studied CYP90B1, CYP90C1, and CYP90D1, suggest that BR biosynthesis proceeds mainly via the campestanol-independent pathway.	Brassinosteroids	132-134	Cytochrome P450 superfamily protein	Arabidopsis thaliana	23-30
22822057-6	2012	Enzyme kinetic data of CYP90A1/CPD and DET2, together with those of the earlier studied CYP90B1, CYP90C1, and CYP90D1, suggest that BR biosynthesis proceeds mainly via the campestanol-independent pathway.	Brassinosteroids	132-134	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	39-43
22822057-6	2012	Enzyme kinetic data of CYP90A1/CPD and DET2, together with those of the earlier studied CYP90B1, CYP90C1, and CYP90D1, suggest that BR biosynthesis proceeds mainly via the campestanol-independent pathway.	Brassinosteroids	132-134	Cytochrome P450 superfamily protein	Arabidopsis thaliana	97-104
22822057-6	2012	Enzyme kinetic data of CYP90A1/CPD and DET2, together with those of the earlier studied CYP90B1, CYP90C1, and CYP90D1, suggest that BR biosynthesis proceeds mainly via the campestanol-independent pathway.	Brassinosteroids	132-134	cytochrome P450, family 90, subfamily D, polypeptide 1	Arabidopsis thaliana	110-117
22463079-0	2012	The cyclophilin ROC1 links phytochrome and cryptochrome to brassinosteroid sensitivity.	Brassinosteroids	59-74	ring-box 1	Homo sapiens	16-20
22463079-5	2012	Mutations at brassinosteroid signalling genes and the application of a brassinosteroid synthesis inhibitor eliminated the roc1 and roc1-D phenotypes.	Brassinosteroids	13-28	ring-box 1	Homo sapiens	122-126
22463079-5	2012	Mutations at brassinosteroid signalling genes and the application of a brassinosteroid synthesis inhibitor eliminated the roc1 and roc1-D phenotypes.	Brassinosteroids	13-28	ring-box 1	Homo sapiens	131-135
22463079-6	2012	The roc1 and roc1-D mutants show altered patterns of phosphorylation of the transcription factor BES1, a known point of control of sensitivity to brassinosteroids, which correlate with the expression levels of genes directly targeted by BES1.	Brassinosteroids	146-162	ring-box 1	Homo sapiens	4-8
22463079-6	2012	The roc1 and roc1-D mutants show altered patterns of phosphorylation of the transcription factor BES1, a known point of control of sensitivity to brassinosteroids, which correlate with the expression levels of genes directly targeted by BES1.	Brassinosteroids	146-162	ring-box 1	Homo sapiens	13-17
22698285-4	2012	We show that BR alters actin configuration and PIN2 localization in a manner similar to that of auxin.	Brassinosteroids	13-15	telomeric repeat binding factor 1	Homo sapiens	47-51
22698285-5	2012	We describe a BR constitutive-response mutant that bears an allele of the ACTIN2 gene and shows altered actin configuration, PIN2 delocalization, and a broad array of phenotypes that recapitulate BR-treated plants.	Brassinosteroids	14-16	telomeric repeat binding factor 1	Homo sapiens	125-129
22525267-6	2012	Although BR signaling pathway is completely disrupted in the serk1 bak1 bkk1 triple mutant, the root growth of the triple mutant is much severely damaged than the BR deficiency or signaling null mutants.	Brassinosteroids	163-165	somatic embryogenesis receptor-like kinase 1	Arabidopsis thaliana	61-66
22561410-2	2012	One of the best-studied leucine-rich repeat receptor-like kinases in plants, BRASSINOSTEROID INSENSITIVE 1 (BRI1), perceives its ligand, the brassinosteroid (BR) hormone, at the cell surface and is constitutively endocytosed.	Brassinosteroids	77-92	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	108-112
22544867-4	2012	We isolated two gain-of-function mutants, brassinosteroid inactivator1-1Dominant (bia1-1D) and bia1-2D, in which a novel BAHD acyltransferase-like protein was transcriptionally activated.	Brassinosteroids	42-57	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	82-86
22544867-6	2012	Exogenous BR treatment rescued the phenotypes of the bia1-1D mutant.	Brassinosteroids	10-12	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	53-57
22544867-7	2012	Endogenous levels of BRs were reduced in the bia1-1D mutant, demonstrating that BIA1 regulates endogenous BR levels.	Brassinosteroids	21-24	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	45-49
22544867-7	2012	Endogenous levels of BRs were reduced in the bia1-1D mutant, demonstrating that BIA1 regulates endogenous BR levels.	Brassinosteroids	21-24	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	80-84
22544867-7	2012	Endogenous levels of BRs were reduced in the bia1-1D mutant, demonstrating that BIA1 regulates endogenous BR levels.	Brassinosteroids	21-23	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	45-49
22544867-7	2012	Endogenous levels of BRs were reduced in the bia1-1D mutant, demonstrating that BIA1 regulates endogenous BR levels.	Brassinosteroids	21-23	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	80-84
22544867-8	2012	When grown in darkness, the bia1 loss-of-function mutant showed a longer hypocotyl phenotype and was more responsive to exogenous BR treatment than the wild-type plant.	Brassinosteroids	130-132	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	28-32
22544867-10	2012	These results indicate that the BAHD acyltransferase family member encoded by BIA1 plays a role in controlling BR levels, particularly in the root and hypocotyl in darkness.	Brassinosteroids	111-113	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	78-82
22685166-9	2012	These results demonstrate that DLT is a GSK2 substrate, further reinforcing that the BIN2/GSK2 kinase has multiple substrates that carry out various BR responses.	Brassinosteroids	149-151	Protein kinase superfamily protein	Arabidopsis thaliana	85-89
22561410-4	2012	Here we developed a bioactive, fluorescent BR analog, Alexa Fluor 647-castasterone (AFCS), and visualized the endocytosis of BRI1-AFCS complexes in living Arabidopsis thaliana cells.	Brassinosteroids	43-45	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	125-129
22535582-0	2012	BZS1, a B-box protein, promotes photomorphogenesis downstream of both brassinosteroid and light signaling pathways.	Brassinosteroids	70-85	gamma-butyrobetaine hydroxylase 1	Homo sapiens	8-13
22331621-7	2012	In addition to PIF4, PAR1 also interacts with PRE1, a HLH transcription factor activated by brassinosteroid (BR) and GA. Overexpression of PRE1 largely suppressed the dwarf phenotype of PAR1OX.	Brassinosteroids	92-107	Prader Willi/Angelman region RNA 1	Homo sapiens	21-25
22331621-7	2012	In addition to PIF4, PAR1 also interacts with PRE1, a HLH transcription factor activated by brassinosteroid (BR) and GA. Overexpression of PRE1 largely suppressed the dwarf phenotype of PAR1OX.	Brassinosteroids	92-107	Prader Willi/Angelman region RNA 1	Homo sapiens	186-192
22213809-11	2012	A transcription factor isolated in the screen is similar to BES1/BLZ1 from Arabidopsis, which is known to be a key transcriptional regulator of the brassinosteroid signalling pathway.	Brassinosteroids	148-163	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	60-64
22466366-4	2012	Here, we show that in addition to MAPKs, SPCH activity is also modulated by brassinosteroid (BR) signalling.	Brassinosteroids	76-91	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	41-45
22196800-3	2012	In Arabidopsis (Arabidopsis thaliana), C-22 hydroxylation of BRs is catalyzed by CYP90B1 (encoded by DWF4) and null dwf4 mutants show severe symptoms of BR-deficiency.	Brassinosteroids	61-64	Cytochrome P450 superfamily protein	Arabidopsis thaliana	81-88
22196800-3	2012	In Arabidopsis (Arabidopsis thaliana), C-22 hydroxylation of BRs is catalyzed by CYP90B1 (encoded by DWF4) and null dwf4 mutants show severe symptoms of BR-deficiency.	Brassinosteroids	61-64	Cytochrome P450 superfamily protein	Arabidopsis thaliana	101-105
22196800-3	2012	In Arabidopsis (Arabidopsis thaliana), C-22 hydroxylation of BRs is catalyzed by CYP90B1 (encoded by DWF4) and null dwf4 mutants show severe symptoms of BR-deficiency.	Brassinosteroids	61-64	Cytochrome P450 superfamily protein	Arabidopsis thaliana	116-120
22196800-6	2012	Defects associated with BR deficiency were reversed and a normal growth habit restored in transgenic dwf4-102 and bsf plants overexpressing CYP724A1.	Brassinosteroids	24-26	Cytochrome P450 superfamily protein	Arabidopsis thaliana	101-105
22196800-6	2012	Defects associated with BR deficiency were reversed and a normal growth habit restored in transgenic dwf4-102 and bsf plants overexpressing CYP724A1.	Brassinosteroids	24-26	cytochrome P450, family 724, subfamily A, polypeptide 1	Arabidopsis thaliana	140-148
21947665-1	2012	Brassinosteroids (BRs) play a crucial role in plant growth and development and DIMINUTO 1 (DIM1), a protein involved in BR biosynthesis, was previously identified as a cell elongation factor in Arabidopsis thaliana.	Brassinosteroids	0-16	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	79-89
22427336-8	2012	In addition, complex formation between the MAMP receptor flagellin sensing2 and its signaling partner brassinosteroid insensitive1-associated kinase1 is observed in flg22-treated lecrk-VI.2-1 mutants.	Brassinosteroids	102-117	lectin receptor kinase a4.1	Arabidopsis thaliana	179-189
21947665-1	2012	Brassinosteroids (BRs) play a crucial role in plant growth and development and DIMINUTO 1 (DIM1), a protein involved in BR biosynthesis, was previously identified as a cell elongation factor in Arabidopsis thaliana.	Brassinosteroids	18-21	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	79-89
21947665-1	2012	Brassinosteroids (BRs) play a crucial role in plant growth and development and DIMINUTO 1 (DIM1), a protein involved in BR biosynthesis, was previously identified as a cell elongation factor in Arabidopsis thaliana.	Brassinosteroids	18-20	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	79-89
22131160-8	2012	On the other hand, dwarf1 seedlings, showing a reduced BR level, exhibited decreased root growth inhibition in response to Cd compared with WT, reversed by the addition of eBL.	Brassinosteroids	55-57	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	19-25
22307275-4	2012	Here we demonstrate in Arabidopsis that brassinosteroid regulates stomatal development by activating the MAPK kinase kinase (MAPKKK) YDA (also known as YODA).	Brassinosteroids	40-55	Protein kinase superfamily protein	Arabidopsis thaliana	152-156
22307275-5	2012	Genetic analyses indicate that receptor kinase-mediated brassinosteroid signalling inhibits stomatal development through the glycogen synthase kinase 3 (GSK3)-like kinase BIN2, and BIN2 acts upstream of YDA but downstream of the ERECTA family of receptor kinases.	Brassinosteroids	56-71	Protein kinase superfamily protein	Arabidopsis thaliana	171-175
22307275-6	2012	Complementary in vitro and in vivo assays show that BIN2 phosphorylates YDA to inhibit YDA phosphorylation of its substrate MKK4, and that activities of downstream MAPKs are reduced in brassinosteroid-deficient mutants but increased by treatment with either brassinosteroid or GSK3-kinase inhibitor.	Brassinosteroids	185-200	Protein kinase superfamily protein	Arabidopsis thaliana	52-56
23124966-2	2012	It has recently been demonstrated that brassinosteroids control stomatal development by regulating both the MAPK kinase kinase YODA and the basic helix-loop-helix transcriptional factor SPEECHLESS.	Brassinosteroids	39-55	Protein kinase superfamily protein	Arabidopsis thaliana	127-131
22087006-2	2012	In Arabidopsis, the regulatory leucine-rich repeat receptor-like kinase (LRR-RLK) BAK1 combines with the LRR-RLKs FLS2 and EFR in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) and the LRR-RLK BRI1 in brassinosteroid (BR)-mediated growth.	Brassinosteroids	224-239	BRI1-associated receptor kinase	Arabidopsis thaliana	82-86
22087006-2	2012	In Arabidopsis, the regulatory leucine-rich repeat receptor-like kinase (LRR-RLK) BAK1 combines with the LRR-RLKs FLS2 and EFR in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) and the LRR-RLK BRI1 in brassinosteroid (BR)-mediated growth.	Brassinosteroids	224-239	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	114-118
23124966-4	2012	Hormone tests, reporter gene studies and mutant analyses revealed that brassinosteroids act upstream of the transcriptional factors CAPRICE and GLABRA2.	Brassinosteroids	71-87	Homeodomain-like superfamily protein	Arabidopsis thaliana	132-139
23124966-4	2012	Hormone tests, reporter gene studies and mutant analyses revealed that brassinosteroids act upstream of the transcriptional factors CAPRICE and GLABRA2.	Brassinosteroids	71-87	HD-ZIP IV family of homeobox-leucine zipper protein with lipid-binding START domain-containing protein	Arabidopsis thaliana	144-151
22301961-4	2012	We hypothesize that EXL1 suppresses brassinosteroid-dependent growth and controls C allocation in the cell.	Brassinosteroids	36-51	Phosphate-responsive 1 family protein	Arabidopsis thaliana	20-24
22214659-0	2012	Arabidopsis ubiquitin conjugase UBC32 is an ERAD component that functions in brassinosteroid-mediated salt stress tolerance.	Brassinosteroids	77-92	ubiquitin-conjugating enzyme 32	Arabidopsis thaliana	32-37
22214659-3	2012	Here, we report that the Arabidopsis thaliana ubiquitin-conjugating enzyme, UBC32, a stress-induced functional ubiquitin conjugation enzyme (E2) localized to the ER membrane, connects the ERAD process and brassinosteroid (BR)-mediated growth promotion and salt stress tolerance.	Brassinosteroids	205-220	ubiquitin-conjugating enzyme 32	Arabidopsis thaliana	76-81
22214659-3	2012	Here, we report that the Arabidopsis thaliana ubiquitin-conjugating enzyme, UBC32, a stress-induced functional ubiquitin conjugation enzyme (E2) localized to the ER membrane, connects the ERAD process and brassinosteroid (BR)-mediated growth promotion and salt stress tolerance.	Brassinosteroids	222-224	ubiquitin-conjugating enzyme 32	Arabidopsis thaliana	76-81
22075146-1	2011	The plasma membrane-localized plant steroid hormone receptor, BRASSINOSTEROID INSENSITIVE 1 (BRI1), is quiescent in the absence of steroids, largely due to a negative regulator, BRI1 KINASE INHIBITOR 1 (BKI1).	Brassinosteroids	62-77	protein phosphatase 1 regulatory inhibitor subunit 1A	Homo sapiens	190-201
23071642-0	2012	Arabidopsis PIZZA has the capacity to acylate brassinosteroids.	Brassinosteroids	46-62	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	12-17
23071642-3	2012	The phenotype of these lines, caused by an overexpression of a putative acyltransferase gene PIZZA (PIZ), was partly rescued by supplying exogenous brassinolide (BL) and castasterone (CS), indicating that endogenous BR levels are rate-limiting for the growth of PIZ overexpression lines.	Brassinosteroids	216-218	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	93-98
23071642-3	2012	The phenotype of these lines, caused by an overexpression of a putative acyltransferase gene PIZZA (PIZ), was partly rescued by supplying exogenous brassinolide (BL) and castasterone (CS), indicating that endogenous BR levels are rate-limiting for the growth of PIZ overexpression lines.	Brassinosteroids	216-218	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	93-96
23071642-3	2012	The phenotype of these lines, caused by an overexpression of a putative acyltransferase gene PIZZA (PIZ), was partly rescued by supplying exogenous brassinolide (BL) and castasterone (CS), indicating that endogenous BR levels are rate-limiting for the growth of PIZ overexpression lines.	Brassinosteroids	216-218	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	100-103
23071642-5	2012	Taking the advantage of relatively high endogenous BR accumulation in a mild bri1-301 background, we found that overexpression of PIZ results in moderately reduced levels of BL and CS and a strong reduction of typhasterol (TY) and 6-deoxocastasterone (6-deoxoCS), suggesting a role of PIZ in BR metabolism.	Brassinosteroids	51-53	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	130-133
23071642-8	2012	Together, our data suggest that PIZ can modify BRs by acylation and that these properties might help modulating endogenous BR levels in Arabidopsis.	Brassinosteroids	47-50	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	32-35
23071642-8	2012	Together, our data suggest that PIZ can modify BRs by acylation and that these properties might help modulating endogenous BR levels in Arabidopsis.	Brassinosteroids	47-49	HXXXD-type acyl-transferase family protein	Arabidopsis thaliana	32-35
21819976-0	2011	Brassinosteroids regulate pectin methylesterase activity and AtPME41 expression in Arabidopsis under chilling stress.	Brassinosteroids	0-16	Plant invertase/pectin methylesterase inhibitor superfamily	Arabidopsis thaliana	61-68
21715650-0	2011	Arabidopsis MSBP1 is activated by HY5 and HYH and is involved in photomorphogenesis and brassinosteroid sensitivity regulation.	Brassinosteroids	88-103	membrane steroid binding protein 1	Arabidopsis thaliana	12-17
21715650-1	2011	Membrane Steroid Binding Protein 1 (MSBP1) can bind steroids in vitro and negatively regulates brassinosteroid (BR) signaling, as well as cell elongation and expansion.	Brassinosteroids	95-110	membrane steroid binding protein 1	Arabidopsis thaliana	0-34
21715650-1	2011	Membrane Steroid Binding Protein 1 (MSBP1) can bind steroids in vitro and negatively regulates brassinosteroid (BR) signaling, as well as cell elongation and expansion.	Brassinosteroids	95-110	membrane steroid binding protein 1	Arabidopsis thaliana	36-41
21571540-10	2011	Interestingly, NAP1;2 was found to be post-translationally modified in response to cellular BR levels.	Brassinosteroids	92-94	nucleosome assembly protein 1;2	Arabidopsis thaliana	15-21
21762167-7	2011	Our findings, in addition to strengthening already known mechanisms, revealed the existence of a new complex signaling framework in which brassinosteroids (BRI1), the module MKK2-MAPK6 and the fine regulation of nitric oxide homeostasis via the co-expression of synthetic (nitrate reductase) and scavenging (hemoglobin) components may play key functions in maize responses to nitrate.	Brassinosteroids	138-154	nitrate reductase [NADH] 1	Zea mays	262-290
21762167-7	2011	Our findings, in addition to strengthening already known mechanisms, revealed the existence of a new complex signaling framework in which brassinosteroids (BRI1), the module MKK2-MAPK6 and the fine regulation of nitric oxide homeostasis via the co-expression of synthetic (nitrate reductase) and scavenging (hemoglobin) components may play key functions in maize responses to nitrate.	Brassinosteroids	138-154	non-symbiotic hemoglobin	Zea mays	308-318
21545406-2	2011	Previously, we isolated the psc1 mutant that partially suppressed coi1 insensitivity to JA, and found that brassinosteroid (BR) was involved in JA signaling and negatively regulated JA inhibition of root growth in Arabidopsis.	Brassinosteroids	107-122	Cytochrome P450 superfamily protein	Arabidopsis thaliana	28-32
21855796-0	2011	The CDG1 kinase mediates brassinosteroid signal transduction from BRI1 receptor kinase to BSU1 phosphatase and GSK3-like kinase BIN2.	Brassinosteroids	25-40	phosphomannomutase 2	Homo sapiens	4-8
21855796-0	2011	The CDG1 kinase mediates brassinosteroid signal transduction from BRI1 receptor kinase to BSU1 phosphatase and GSK3-like kinase BIN2.	Brassinosteroids	25-40	bridging integrator 2	Homo sapiens	128-132
21545406-2	2011	Previously, we isolated the psc1 mutant that partially suppressed coi1 insensitivity to JA, and found that brassinosteroid (BR) was involved in JA signaling and negatively regulated JA inhibition of root growth in Arabidopsis.	Brassinosteroids	124-126	Cytochrome P450 superfamily protein	Arabidopsis thaliana	28-32
21617031-4	2011	As a proof of principle, we quantified the Brassinosteroid Insensitive1 (BRI1) receptor fused to GFP, under control of its own promoter.	Brassinosteroids	43-58	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	73-77
21284753-3	2011	Among the enzymes involved in BR biosynthesis in Arabidopsis (Arabidopsis thaliana), DWARF4 catalyzes the rate-determining step.	Brassinosteroids	30-32	Cytochrome P450 superfamily protein	Arabidopsis thaliana	85-91
21701259-3	2011	Protein phosphatase 2A (PP2A) is involved in auxin, abscisic acid, ethylene and brassinosteroid signaling and now emerges as a positive and negative multilevel regulator of plant HMGR, both during normal growth and in response to a variety of stress conditions.	Brassinosteroids	80-95	protein phosphatase 2 phosphatase activator	Homo sapiens	8-22
21701259-3	2011	Protein phosphatase 2A (PP2A) is involved in auxin, abscisic acid, ethylene and brassinosteroid signaling and now emerges as a positive and negative multilevel regulator of plant HMGR, both during normal growth and in response to a variety of stress conditions.	Brassinosteroids	80-95	protein phosphatase 2 phosphatase activator	Homo sapiens	24-28
21617383-1	2011	The plasma membrane-spanning receptor brassinosteroid insenstive 1 (BRI1) rapidly induces plant cell wall expansion in response to brassinosteroids such as brassinolide (BL).	Brassinosteroids	131-147	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	4-72
21693696-3	2011	Using coimmunoprecipitation and mass spectrometry analyses, we demonstrated that EFR and FLS2 undergo ligand-induced heteromerization in planta with several LRR receptor-like kinases that belong to the SOMATIC-EMBRYOGENESIS RECEPTOR-LIKE KINASE (SERK) family, including BRASSINOSTEROID INSENSITIVE1-ASSOCIATED KINASE1/SERK3 (BAK1/SERK3) and BAK1-LIKE1/SERK4 (BKK1/SERK4).	Brassinosteroids	270-285	EF-TU receptor	Arabidopsis thaliana	81-84
21693696-3	2011	Using coimmunoprecipitation and mass spectrometry analyses, we demonstrated that EFR and FLS2 undergo ligand-induced heteromerization in planta with several LRR receptor-like kinases that belong to the SOMATIC-EMBRYOGENESIS RECEPTOR-LIKE KINASE (SERK) family, including BRASSINOSTEROID INSENSITIVE1-ASSOCIATED KINASE1/SERK3 (BAK1/SERK3) and BAK1-LIKE1/SERK4 (BKK1/SERK4).	Brassinosteroids	270-285	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	89-93
21418356-2	2011	In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation.	Brassinosteroids	35-51	Cytochrome P450 superfamily protein	Arabidopsis thaliana	162-170
21418356-2	2011	In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation.	Brassinosteroids	35-51	Cytochrome P450 superfamily protein	Arabidopsis thaliana	171-175
21418356-2	2011	In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation.	Brassinosteroids	35-51	cytochrome p450 72c1	Arabidopsis thaliana	180-187
21418356-2	2011	In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation.	Brassinosteroids	35-51	cytochrome p450 72c1	Arabidopsis thaliana	188-192
21418356-2	2011	In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation.	Brassinosteroids	35-51	cytochrome p450 72c1	Arabidopsis thaliana	193-197
21418356-2	2011	In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation.	Brassinosteroids	35-51	cytochrome p450 72c1	Arabidopsis thaliana	198-202
21418356-2	2011	In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation.	Brassinosteroids	35-51	Cytochrome P450 superfamily protein	Arabidopsis thaliana	204-212
21418356-2	2011	In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation.	Brassinosteroids	35-51	Cytochrome P450 superfamily protein	Arabidopsis thaliana	213-217
21491949-0	2011	Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells.	Brassinosteroids	57-73	AKT serine/threonine kinase 1	Rattus norvegicus	0-3
21491949-4	2011	All anabolic brassinosteroids tested in this study selectively activated PI3K/Akt signaling pathway as evident by increased Akt phosphorylation in vitro.	Brassinosteroids	13-29	AKT serine/threonine kinase 1	Rattus norvegicus	78-81
21491949-4	2011	All anabolic brassinosteroids tested in this study selectively activated PI3K/Akt signaling pathway as evident by increased Akt phosphorylation in vitro.	Brassinosteroids	13-29	AKT serine/threonine kinase 1	Rattus norvegicus	124-127
21558552-0	2011	PP2A phosphatases: the "on-off" regulatory switches of brassinosteroid signaling.	Brassinosteroids	55-70	serine/threonine protein phosphatase 2A	Arabidopsis thaliana	0-4
21558554-4	2011	We report the identification, in A. thaliana, of a suppressor of bri1, sbi1, which caused selective accumulation of BR-activated BRI1, but not the BR co-receptor BAK1 (BRI1-ASSOCIATED KINASE 1), in the membranous compartment.	Brassinosteroids	116-118	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	65-69
21558554-4	2011	We report the identification, in A. thaliana, of a suppressor of bri1, sbi1, which caused selective accumulation of BR-activated BRI1, but not the BR co-receptor BAK1 (BRI1-ASSOCIATED KINASE 1), in the membranous compartment.	Brassinosteroids	116-118	Leucine carboxyl methyltransferase	Arabidopsis thaliana	71-75
21558554-4	2011	We report the identification, in A. thaliana, of a suppressor of bri1, sbi1, which caused selective accumulation of BR-activated BRI1, but not the BR co-receptor BAK1 (BRI1-ASSOCIATED KINASE 1), in the membranous compartment.	Brassinosteroids	116-118	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	129-133
21336258-0	2011	CESTA, a positive regulator of brassinosteroid biosynthesis.	Brassinosteroids	31-46	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	0-5
21487098-2	2011	They possess BRASSINAZOLE RESISTANT1 (BZR1)-type DNA binding domains--also found in transcription factors mediating brassinosteroid (BR) responses.	Brassinosteroids	116-131	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	38-42
21336258-4	2011	In this study, we identify the transcription factor CESTA as a regulator of BR biosynthesis.	Brassinosteroids	76-78	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	52-57
21336258-6	2011	Loss-of-function analysis and the use of a dominant repressor version revealed functional overlap among CESTA and its homologues and confirmed the role of CESTA in the positive control of BR-biosynthetic gene expression.	Brassinosteroids	188-190	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	104-109
21336258-6	2011	Loss-of-function analysis and the use of a dominant repressor version revealed functional overlap among CESTA and its homologues and confirmed the role of CESTA in the positive control of BR-biosynthetic gene expression.	Brassinosteroids	188-190	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	155-160
21336258-8	2011	Moreover, we show that CESTA subnuclear localization is BR regulated and discuss a model, in which CESTA interplays with BEE1 to control BR biosynthesis and other BR responses.	Brassinosteroids	56-58	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	23-28
21336258-8	2011	Moreover, we show that CESTA subnuclear localization is BR regulated and discuss a model, in which CESTA interplays with BEE1 to control BR biosynthesis and other BR responses.	Brassinosteroids	56-58	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	99-104
21336258-8	2011	Moreover, we show that CESTA subnuclear localization is BR regulated and discuss a model, in which CESTA interplays with BEE1 to control BR biosynthesis and other BR responses.	Brassinosteroids	56-58	BR enhanced expression 1	Arabidopsis thaliana	121-125
21909364-0	2011	Transcription of DWARF4 plays a crucial role in auxin-regulated root elongation in addition to brassinosteroid homeostasis in Arabidopsis thaliana.	Brassinosteroids	95-110	Cytochrome P450 superfamily protein	Arabidopsis thaliana	17-23
21270057-4	2011	In the BR-insensitive bri1-116 mutant, the expression pattern of the cell division markers CYCB1;1, ICK2/KRP2 and KNOLLE revealed that a decreased mitotic activity accounts for the reduced meristem size; accordingly, this defect could be overcome by the overexpression of CYCD3;1.	Brassinosteroids	7-9	CYCLIN B1;1	Arabidopsis thaliana	91-96
21270057-4	2011	In the BR-insensitive bri1-116 mutant, the expression pattern of the cell division markers CYCB1;1, ICK2/KRP2 and KNOLLE revealed that a decreased mitotic activity accounts for the reduced meristem size; accordingly, this defect could be overcome by the overexpression of CYCD3;1.	Brassinosteroids	7-9	KIP-related protein 2	Arabidopsis thaliana	100-104
21270057-4	2011	In the BR-insensitive bri1-116 mutant, the expression pattern of the cell division markers CYCB1;1, ICK2/KRP2 and KNOLLE revealed that a decreased mitotic activity accounts for the reduced meristem size; accordingly, this defect could be overcome by the overexpression of CYCD3;1.	Brassinosteroids	7-9	KIP-related protein 2	Arabidopsis thaliana	105-109
21270057-4	2011	In the BR-insensitive bri1-116 mutant, the expression pattern of the cell division markers CYCB1;1, ICK2/KRP2 and KNOLLE revealed that a decreased mitotic activity accounts for the reduced meristem size; accordingly, this defect could be overcome by the overexpression of CYCD3;1.	Brassinosteroids	7-9	CYCLIN D3;1	Arabidopsis thaliana	272-277
21289069-2	2011	Recently, two Arabidopsis receptor kinases--BRASSINOSTEROID INSENSITIVE 1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1), the receptor and coreceptor for brassinosteroids--were shown to autophosphorylate on tyrosines.	Brassinosteroids	149-165	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	35-73
21289069-2	2011	Recently, two Arabidopsis receptor kinases--BRASSINOSTEROID INSENSITIVE 1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1), the receptor and coreceptor for brassinosteroids--were shown to autophosphorylate on tyrosines.	Brassinosteroids	149-165	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	75-79
21289069-2	2011	Recently, two Arabidopsis receptor kinases--BRASSINOSTEROID INSENSITIVE 1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1), the receptor and coreceptor for brassinosteroids--were shown to autophosphorylate on tyrosines.	Brassinosteroids	149-165	BRI1-associated receptor kinase	Arabidopsis thaliana	85-108
21289069-2	2011	Recently, two Arabidopsis receptor kinases--BRASSINOSTEROID INSENSITIVE 1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1), the receptor and coreceptor for brassinosteroids--were shown to autophosphorylate on tyrosines.	Brassinosteroids	149-165	BRI1-associated receptor kinase	Arabidopsis thaliana	110-114
21289069-4	2011	Here, we report that the BRI1 KINASE INHIBITOR 1 (BKI1) is tyrosine phosphorylated in response to brassinosteroid perception.	Brassinosteroids	98-113	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	25-29
21289069-4	2011	Here, we report that the BRI1 KINASE INHIBITOR 1 (BKI1) is tyrosine phosphorylated in response to brassinosteroid perception.	Brassinosteroids	98-113	BRI1 kinase inhibitor 1	Arabidopsis thaliana	50-54
21134899-5	2011	BR treatment increased the content of ABA and up-regulated the expression of the ABA biosynthetic gene vp14 in maize leaves, which was blocked by pre-treatments with the NO scavenger cPTIO (2,4-carboxyphenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide) and the nitric oxide synthase inhibitor l-NAME (N(G)-nitro-l-arginine methyl ester.	Brassinosteroids	0-2	9-cis-epoxycarotenoid dioxygenase 1, chloroplastic	Zea mays	103-107
21429230-6	2011	RESULTS: In a candidate gene approach, in which homologues of UGT73C5 were screened for their potential to induce BR deficiency when over-expressed in plants, UGT73C6 was identified as an enzyme that can glucosylate the BRs CS and BL at their 23-O-positions in planta.	Brassinosteroids	114-116	don-glucosyltransferase 1	Arabidopsis thaliana	62-69
21429230-6	2011	RESULTS: In a candidate gene approach, in which homologues of UGT73C5 were screened for their potential to induce BR deficiency when over-expressed in plants, UGT73C6 was identified as an enzyme that can glucosylate the BRs CS and BL at their 23-O-positions in planta.	Brassinosteroids	114-116	UDP-glucosyl transferase 73C6	Arabidopsis thaliana	159-166
21205622-6	2011	Both leaf and root growth were synergistically enhanced in plants ectopically expressing CKX3 and BRASSINOSTEROID INSENSITIVE1, indicating cross talk between cytokinins and brassinosteroids.	Brassinosteroids	173-189	cytokinin oxidase 3	Arabidopsis thaliana	89-93
21258370-0	2011	PP2A activates brassinosteroid-responsive gene expression and plant growth by dephosphorylating BZR1.	Brassinosteroids	15-30	protein phosphatase 2 phosphatase activator	Homo sapiens	0-4
21258370-1	2011	When brassinosteroid levels are low, the GSK3-like kinase BIN2 phosphorylates and inactivates the BZR1 transcription factor to inhibit growth in plants.	Brassinosteroids	5-20	bridging integrator 2	Homo sapiens	58-62
21214652-2	2011	BRs signal to control the activities of the BES1 and BZR1 family transcription factors.	Brassinosteroids	0-3	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	44-48
21909364-1	2011	The expression of DWARF4 (DWF4), which encodes a C-22 hydroxylase, is crucial for brassinosteroid (BR) biosynthesis and for the feedback control of endogenous BR levels.	Brassinosteroids	82-97	Cytochrome P450 superfamily protein	Arabidopsis thaliana	18-24
21909364-1	2011	The expression of DWARF4 (DWF4), which encodes a C-22 hydroxylase, is crucial for brassinosteroid (BR) biosynthesis and for the feedback control of endogenous BR levels.	Brassinosteroids	82-97	Cytochrome P450 superfamily protein	Arabidopsis thaliana	26-30
21909364-1	2011	The expression of DWARF4 (DWF4), which encodes a C-22 hydroxylase, is crucial for brassinosteroid (BR) biosynthesis and for the feedback control of endogenous BR levels.	Brassinosteroids	99-101	Cytochrome P450 superfamily protein	Arabidopsis thaliana	18-24
21909364-1	2011	The expression of DWARF4 (DWF4), which encodes a C-22 hydroxylase, is crucial for brassinosteroid (BR) biosynthesis and for the feedback control of endogenous BR levels.	Brassinosteroids	99-101	Cytochrome P450 superfamily protein	Arabidopsis thaliana	26-30
21909364-1	2011	The expression of DWARF4 (DWF4), which encodes a C-22 hydroxylase, is crucial for brassinosteroid (BR) biosynthesis and for the feedback control of endogenous BR levels.	Brassinosteroids	159-161	Cytochrome P450 superfamily protein	Arabidopsis thaliana	18-24
21909364-1	2011	The expression of DWARF4 (DWF4), which encodes a C-22 hydroxylase, is crucial for brassinosteroid (BR) biosynthesis and for the feedback control of endogenous BR levels.	Brassinosteroids	159-161	Cytochrome P450 superfamily protein	Arabidopsis thaliana	26-30
20616146-7	2010	Thus, SSP has diverged in function after duplication from a component of the brassinosteroid signaling pathway to a paternal regulator of the timing of zygote elongation.	Brassinosteroids	77-92	kinase with tetratricopeptide repeat domain-containing protein	Arabidopsis thaliana	6-9
21145502-3	2010	Overexpression of GATA2 causes constitutive photomorphogenesis in the dark, whereas suppression of GATA2 reduces photomorphogenesis caused by light, BR deficiency, or the constitutive photomorphogenesis mutant cop1.	Brassinosteroids	149-151	GATA transcription factor 2	Arabidopsis thaliana	99-104
21143877-6	2010	We found that the DWARF4 gene which encodes for an enzyme catalyzing a rate-determining step in the BR biosynthetic pathways, is highly expressed in the actively dividing callus, suggesting that BR biosynthesis is necessary for dividing cells.	Brassinosteroids	100-102	Cytochrome P450 superfamily protein	Arabidopsis thaliana	18-24
21143877-6	2010	We found that the DWARF4 gene which encodes for an enzyme catalyzing a rate-determining step in the BR biosynthetic pathways, is highly expressed in the actively dividing callus, suggesting that BR biosynthesis is necessary for dividing cells.	Brassinosteroids	195-197	Cytochrome P450 superfamily protein	Arabidopsis thaliana	18-24
20685730-2	2010	In Arabidopsis, BR biosynthetic det2 mutants exhibited delayed flowering time by at least 10 d compared with the wild type.	Brassinosteroids	16-18	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	32-36
20238175-7	2010	The expression of BnGA1 was significantly induced by the high concentrations of abscisic acid (ABA) and brassinosteroid (BR).	Brassinosteroids	104-119	guanine nucleotide-binding protein alpha-1 subunit	Brassica napus	18-23
20238175-7	2010	The expression of BnGA1 was significantly induced by the high concentrations of abscisic acid (ABA) and brassinosteroid (BR).	Brassinosteroids	121-123	guanine nucleotide-binding protein alpha-1 subunit	Brassica napus	18-23
20861670-6	2010	Overexpression of a constitutively active RabG3b (RabG3bCA) significantly enhances both autophagy and TE differentiation, which are consistently suppressed in transgenic plants overexpressing a dominant negative form (RabG3bDN) or RabG3b RNAi (RabG3bRNAi), a brassinosteroid-insensitive mutant bri1-301 and an autophagy mutant atg5-1.	Brassinosteroids	259-274	RAB GTPase homolog G3B	Arabidopsis thaliana	42-48
20861670-6	2010	Overexpression of a constitutively active RabG3b (RabG3bCA) significantly enhances both autophagy and TE differentiation, which are consistently suppressed in transgenic plants overexpressing a dominant negative form (RabG3bDN) or RabG3b RNAi (RabG3bRNAi), a brassinosteroid-insensitive mutant bri1-301 and an autophagy mutant atg5-1.	Brassinosteroids	259-274	RAB GTPase homolog G3B	Arabidopsis thaliana	50-56
20685730-3	2010	The levels of endogenous BRs in det2 were below 10% of the wild type.	Brassinosteroids	25-28	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	32-36
20693409-0	2010	ZmMPK5 is required for the NADPH oxidase-mediated self-propagation of apoplastic H2O2 in brassinosteroid-induced antioxidant defence in leaves of maize.	Brassinosteroids	89-104	MAP kinase 2	Zea mays	0-6
20693409-4	2010	BR treatment activated ZmMPK5, induced apoplastic and chloroplastic H(2)O(2) accumulation, and enhanced the total activities of antioxidant enzymes.	Brassinosteroids	0-2	MAP kinase 2	Zea mays	23-29
20935478-0	2010	MOTHER OF FT AND TFL1 regulates seed germination and fertility relevant to the brassinosteroid signaling pathway.	Brassinosteroids	79-94	PEBP (phosphatidylethanolamine-binding protein) family protein	Arabidopsis thaliana	17-21
20935478-6	2010	In addition, mft enhances the low-fertility phenotype of det2 in which BR biosynthesis is blocked.	Brassinosteroids	71-73	PEBP (phosphatidylethanolamine-binding protein) family protein	Arabidopsis thaliana	13-16
20570616-0	2010	Induction of hexokinase I expression in normal and diabetic rats by a brassinosteroid isoform.	Brassinosteroids	70-85	hexokinase 1	Rattus norvegicus	13-25
20649916-2	2010	Physiological and gene expression analyses have suggested that BRX is rate limiting for auxin-responsive gene expression by mediating cross-talk with the brassinosteroid pathway, as impaired root growth and reduced auxin perception of brx can be (partially) rescued by external brassinosteroid application.	Brassinosteroids	154-169	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	63-66
20649916-2	2010	Physiological and gene expression analyses have suggested that BRX is rate limiting for auxin-responsive gene expression by mediating cross-talk with the brassinosteroid pathway, as impaired root growth and reduced auxin perception of brx can be (partially) rescued by external brassinosteroid application.	Brassinosteroids	154-169	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	235-238
20649916-7	2010	Consistent with an impact of BRX on brassinosteroid biosynthesis, this phenotype is accompanied by increased brassinosteroid levels.	Brassinosteroids	36-51	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	29-32
20669042-0	2010	Arabidopsis CYP72C1 is an atypical cytochrome P450 that inactivates brassinosteroids.	Brassinosteroids	68-84	cytochrome p450 72c1	Arabidopsis thaliana	12-19
20669042-2	2010	Two P450s in particular, CYP734A1 and CYP72C1, have been identified as brassinosteroid-inactivating enzymes important for steroid-mediated signal transduction in Arabidopsis thaliana.	Brassinosteroids	71-86	Cytochrome P450 superfamily protein	Arabidopsis thaliana	25-33
20669042-2	2010	Two P450s in particular, CYP734A1 and CYP72C1, have been identified as brassinosteroid-inactivating enzymes important for steroid-mediated signal transduction in Arabidopsis thaliana.	Brassinosteroids	71-86	cytochrome p450 72c1	Arabidopsis thaliana	38-45
20669042-8	2010	Heterologous expression of these P450s followed by substrate binding analyses have indicated that CYP734A1 binds active brassinosteroids, brassinolide and castasterone, as well as their upstream precursors whereas CYP72C1 binds precursors more effectively.	Brassinosteroids	120-136	Cytochrome P450 superfamily protein	Arabidopsis thaliana	98-106
20669042-8	2010	Heterologous expression of these P450s followed by substrate binding analyses have indicated that CYP734A1 binds active brassinosteroids, brassinolide and castasterone, as well as their upstream precursors whereas CYP72C1 binds precursors more effectively.	Brassinosteroids	120-136	cytochrome p450 72c1	Arabidopsis thaliana	214-221
20396969-6	2010	Consistent with this, a gene encoding the CYP72C1 enzyme that catabolizes BR was up-regulated.	Brassinosteroids	74-76	cytochrome p450 72c1	Arabidopsis thaliana	42-49
20421456-5	2010	SMT2 and SMT3, which also encodes a C-24 SMT, catalyze the reaction that distinguishes the synthesis of structural sterols from signaling brassinosteroid derivatives and are highly regulated.	Brassinosteroids	138-153	sterol methyltransferase 2	Arabidopsis thaliana	0-4
20421456-5	2010	SMT2 and SMT3, which also encodes a C-24 SMT, catalyze the reaction that distinguishes the synthesis of structural sterols from signaling brassinosteroid derivatives and are highly regulated.	Brassinosteroids	138-153	sterol methyltransferase 3	Arabidopsis thaliana	9-13
20522560-3	2010	Brassinosteroid-INsensitive 2 (BIN2) is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling by phosphorylating BES1 (bri1 EMS suppressor 1) and BZR1 (brassinazole-resistant 1), two highly similar transcription factors critical for bringing about characteristic BR responses.	Brassinosteroids	98-113	Protein kinase superfamily protein	Arabidopsis thaliana	0-29
20522560-3	2010	Brassinosteroid-INsensitive 2 (BIN2) is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling by phosphorylating BES1 (bri1 EMS suppressor 1) and BZR1 (brassinazole-resistant 1), two highly similar transcription factors critical for bringing about characteristic BR responses.	Brassinosteroids	98-113	Protein kinase superfamily protein	Arabidopsis thaliana	31-35
20522560-3	2010	Brassinosteroid-INsensitive 2 (BIN2) is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling by phosphorylating BES1 (bri1 EMS suppressor 1) and BZR1 (brassinazole-resistant 1), two highly similar transcription factors critical for bringing about characteristic BR responses.	Brassinosteroids	98-113	shaggy	Drosophila melanogaster	55-59
20522560-3	2010	Brassinosteroid-INsensitive 2 (BIN2) is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling by phosphorylating BES1 (bri1 EMS suppressor 1) and BZR1 (brassinazole-resistant 1), two highly similar transcription factors critical for bringing about characteristic BR responses.	Brassinosteroids	98-113	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	154-175
20522560-3	2010	Brassinosteroid-INsensitive 2 (BIN2) is an Arabidopsis GSK3-like kinase that negatively regulates brassinosteroid (BR) signaling by phosphorylating BES1 (bri1 EMS suppressor 1) and BZR1 (brassinazole-resistant 1), two highly similar transcription factors critical for bringing about characteristic BR responses.	Brassinosteroids	98-113	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	181-185
20396969-8	2010	In addition, the ARF8 gene expression was significantly reduced by BR but induced by brassinazole, a BR biosynthetic inhibitor.	Brassinosteroids	67-69	auxin response factor 8	Arabidopsis thaliana	17-21
20396969-10	2010	Our observations indicate that at least part of auxin and BR signaling pathways are unified through a transcriptional feedback control of the DLF and ARF8 genes.	Brassinosteroids	58-60	auxin response factor 8	Arabidopsis thaliana	150-154
20435901-0	2010	TCP1 modulates brassinosteroid biosynthesis by regulating the expression of the key biosynthetic gene DWARF4 in Arabidopsis thaliana.	Brassinosteroids	15-30	T-complex protein 1 alpha subunit	Arabidopsis thaliana	0-4
20169349-3	2010	Triple knock-down of the DET2, DWF4, and SMT2 enzymes also resulted in reduction of brassinosteroid (BR)-specific biosynthesis intermediates.	Brassinosteroids	84-99	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	25-29
20169349-3	2010	Triple knock-down of the DET2, DWF4, and SMT2 enzymes also resulted in reduction of brassinosteroid (BR)-specific biosynthesis intermediates.	Brassinosteroids	84-99	Cytochrome P450 superfamily protein	Arabidopsis thaliana	31-35
20169349-3	2010	Triple knock-down of the DET2, DWF4, and SMT2 enzymes also resulted in reduction of brassinosteroid (BR)-specific biosynthesis intermediates.	Brassinosteroids	84-99	sterol methyltransferase 2	Arabidopsis thaliana	41-45
20169349-3	2010	Triple knock-down of the DET2, DWF4, and SMT2 enzymes also resulted in reduction of brassinosteroid (BR)-specific biosynthesis intermediates.	Brassinosteroids	101-103	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	25-29
20400488-0	2010	FERONIA is a key modulator of brassinosteroid and ethylene responsiveness in Arabidopsis hypocotyls.	Brassinosteroids	30-45	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	0-7
20400488-5	2010	In contrast to a previous report, analysis of our feronia knockout mutant shows it also has altered responsiveness to brassinosteroids, with etiolated fer-2 seedlings being partially brassinosteroid insensitive with regard to promotion of hypocotyl elongation.	Brassinosteroids	118-134	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	50-57
20400488-5	2010	In contrast to a previous report, analysis of our feronia knockout mutant shows it also has altered responsiveness to brassinosteroids, with etiolated fer-2 seedlings being partially brassinosteroid insensitive with regard to promotion of hypocotyl elongation.	Brassinosteroids	118-133	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	50-57
20400488-6	2010	Our results indicate that FERONIA-dependent brassinosteroid response serves to antagonize the effect of ethylene on hypocotyl growth of etiolated seedlings, with loss of proper brassinosteroid signaling disrupting this balance and leading to a greater impact of ethylene on hypocotyl shortening.	Brassinosteroids	44-59	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	26-33
20128883-0	2010	ASKtheta, a group-III Arabidopsis GSK3, functions in the brassinosteroid signalling pathway.	Brassinosteroids	57-72	shaggy-like protein kinase 32	Arabidopsis thaliana	0-8
20128883-2	2010	GSK3/shaggy-like kinases (GSK) are critical regulators of intracellular signalling initiated by the binding of BR to the BRI1 receptor complex.	Brassinosteroids	111-113	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	121-125
20128883-3	2010	Three GSKs have already been shown to relay BR responses, including phosphorylation of the transcriptional regulator BES1.	Brassinosteroids	44-46	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	117-121
20169349-3	2010	Triple knock-down of the DET2, DWF4, and SMT2 enzymes also resulted in reduction of brassinosteroid (BR)-specific biosynthesis intermediates.	Brassinosteroids	101-103	Cytochrome P450 superfamily protein	Arabidopsis thaliana	31-35
20169349-3	2010	Triple knock-down of the DET2, DWF4, and SMT2 enzymes also resulted in reduction of brassinosteroid (BR)-specific biosynthesis intermediates.	Brassinosteroids	101-103	sterol methyltransferase 2	Arabidopsis thaliana	41-45
20435901-0	2010	TCP1 modulates brassinosteroid biosynthesis by regulating the expression of the key biosynthetic gene DWARF4 in Arabidopsis thaliana.	Brassinosteroids	15-30	Cytochrome P450 superfamily protein	Arabidopsis thaliana	102-108
20435901-5	2010	Overexpression of a dominant-negative form of TCP1, TCP1-SRDX, with a 12-amino acid repressor sequence fused to TCP1 at its C terminus, results in dwarfed plants resembling BR-deficient or insensitive mutants.	Brassinosteroids	173-175	T-complex protein 1 alpha subunit	Arabidopsis thaliana	46-50
20435901-5	2010	Overexpression of a dominant-negative form of TCP1, TCP1-SRDX, with a 12-amino acid repressor sequence fused to TCP1 at its C terminus, results in dwarfed plants resembling BR-deficient or insensitive mutants.	Brassinosteroids	173-175	T-complex protein 1 alpha subunit	Arabidopsis thaliana	52-56
20435901-5	2010	Overexpression of a dominant-negative form of TCP1, TCP1-SRDX, with a 12-amino acid repressor sequence fused to TCP1 at its C terminus, results in dwarfed plants resembling BR-deficient or insensitive mutants.	Brassinosteroids	173-175	T-complex protein 1 alpha subunit	Arabidopsis thaliana	52-56
20435901-7	2010	BR profile assay (quantitative analysis of BR biosynthetic intermediates) strongly suggests that TCP1 expression level positively coordinates with the function of DWARF4 (DWF4), a key enzyme in BR biosynthesis.	Brassinosteroids	0-2	T-complex protein 1 alpha subunit	Arabidopsis thaliana	97-101
20435901-7	2010	BR profile assay (quantitative analysis of BR biosynthetic intermediates) strongly suggests that TCP1 expression level positively coordinates with the function of DWARF4 (DWF4), a key enzyme in BR biosynthesis.	Brassinosteroids	0-2	Cytochrome P450 superfamily protein	Arabidopsis thaliana	163-169
20435901-7	2010	BR profile assay (quantitative analysis of BR biosynthetic intermediates) strongly suggests that TCP1 expression level positively coordinates with the function of DWARF4 (DWF4), a key enzyme in BR biosynthesis.	Brassinosteroids	0-2	Cytochrome P450 superfamily protein	Arabidopsis thaliana	171-175
20435901-7	2010	BR profile assay (quantitative analysis of BR biosynthetic intermediates) strongly suggests that TCP1 expression level positively coordinates with the function of DWARF4 (DWF4), a key enzyme in BR biosynthesis.	Brassinosteroids	43-45	T-complex protein 1 alpha subunit	Arabidopsis thaliana	97-101
20435901-7	2010	BR profile assay (quantitative analysis of BR biosynthetic intermediates) strongly suggests that TCP1 expression level positively coordinates with the function of DWARF4 (DWF4), a key enzyme in BR biosynthesis.	Brassinosteroids	43-45	Cytochrome P450 superfamily protein	Arabidopsis thaliana	163-169
20435901-7	2010	BR profile assay (quantitative analysis of BR biosynthetic intermediates) strongly suggests that TCP1 expression level positively coordinates with the function of DWARF4 (DWF4), a key enzyme in BR biosynthesis.	Brassinosteroids	43-45	Cytochrome P450 superfamily protein	Arabidopsis thaliana	171-175
20435901-10	2010	The expression of TCP1 appears to be regulated by BR levels.	Brassinosteroids	50-52	T-complex protein 1 alpha subunit	Arabidopsis thaliana	18-22
20023196-6	2009	This metabolic defect significantly compromises the endoplasmic reticulum-associated degradation of bri1-9 and bri1-5, two defective transmembrane receptors for brassinosteroids.	Brassinosteroids	161-177	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	100-117
20035956-0	2010	Brassinosteroids control AtEXPA5 gene expression in Arabidopsis thaliana.	Brassinosteroids	0-16	expansin A5	Arabidopsis thaliana	25-32
20167108-1	2010	BACKGROUND: Arabidopsis thaliana transthyretin-like (TTL) protein is a potential substrate in the brassinosteroid signalling cascade, having a role that moderates plant growth.	Brassinosteroids	98-113	coiled coil protein	Arabidopsis thaliana	24-51
20167108-1	2010	BACKGROUND: Arabidopsis thaliana transthyretin-like (TTL) protein is a potential substrate in the brassinosteroid signalling cascade, having a role that moderates plant growth.	Brassinosteroids	98-113	coiled coil protein	Arabidopsis thaliana	53-56
20387034-1	2010	Brassinosteroids BRs)play important roles in plant growth and development.BRs modulate the phosphorylation status of two crucial transcription factors, BRI1 EMS SUPPRESSOR1 BES1)and BRASSINAZOLE RESISTANT1 (BZR1).Here we show that BES1 functions as a nucleocytoplasmic signal transmitter, and that its subcellular localization modulates the output intensity of the BR signal.BRASSINOSTEROID INSENSITIVE2 (BIN2)and other group II GLYCOGEN SYNTHASE KINASE 3 GSK3)-like kinases phosphorylate BES1 and induce its nuclear export by regulating its binding affinity with 14-3-3 proteins.We identified twelve putative phosphorylation residues in BES1.Two of these residues, Ser 171 and Thr 175, are critical for interaction with 14-3-3 proteins.The other putative phosphorylation sites in the N-terminal region are required for the BIN2-mediated nuclear export of BES1.Mutations of these motifs result in increased nuclear accumulation of BES1 and enhanced BR responses in transgenic plants.Taken together, our results indicate that the spatial redistribution of BES1 is important for regulation of the BR signaling output.	Brassinosteroids	0-16	bridging integrator 2	Homo sapiens	405-409
20387034-1	2010	Brassinosteroids BRs)play important roles in plant growth and development.BRs modulate the phosphorylation status of two crucial transcription factors, BRI1 EMS SUPPRESSOR1 BES1)and BRASSINAZOLE RESISTANT1 (BZR1).Here we show that BES1 functions as a nucleocytoplasmic signal transmitter, and that its subcellular localization modulates the output intensity of the BR signal.BRASSINOSTEROID INSENSITIVE2 (BIN2)and other group II GLYCOGEN SYNTHASE KINASE 3 GSK3)-like kinases phosphorylate BES1 and induce its nuclear export by regulating its binding affinity with 14-3-3 proteins.We identified twelve putative phosphorylation residues in BES1.Two of these residues, Ser 171 and Thr 175, are critical for interaction with 14-3-3 proteins.The other putative phosphorylation sites in the N-terminal region are required for the BIN2-mediated nuclear export of BES1.Mutations of these motifs result in increased nuclear accumulation of BES1 and enhanced BR responses in transgenic plants.Taken together, our results indicate that the spatial redistribution of BES1 is important for regulation of the BR signaling output.	Brassinosteroids	0-16	bridging integrator 2	Homo sapiens	824-828
20387034-1	2010	Brassinosteroids BRs)play important roles in plant growth and development.BRs modulate the phosphorylation status of two crucial transcription factors, BRI1 EMS SUPPRESSOR1 BES1)and BRASSINAZOLE RESISTANT1 (BZR1).Here we show that BES1 functions as a nucleocytoplasmic signal transmitter, and that its subcellular localization modulates the output intensity of the BR signal.BRASSINOSTEROID INSENSITIVE2 (BIN2)and other group II GLYCOGEN SYNTHASE KINASE 3 GSK3)-like kinases phosphorylate BES1 and induce its nuclear export by regulating its binding affinity with 14-3-3 proteins.We identified twelve putative phosphorylation residues in BES1.Two of these residues, Ser 171 and Thr 175, are critical for interaction with 14-3-3 proteins.The other putative phosphorylation sites in the N-terminal region are required for the BIN2-mediated nuclear export of BES1.Mutations of these motifs result in increased nuclear accumulation of BES1 and enhanced BR responses in transgenic plants.Taken together, our results indicate that the spatial redistribution of BES1 is important for regulation of the BR signaling output.	Brassinosteroids	375-390	bridging integrator 2	Homo sapiens	405-409
20387034-1	2010	Brassinosteroids BRs)play important roles in plant growth and development.BRs modulate the phosphorylation status of two crucial transcription factors, BRI1 EMS SUPPRESSOR1 BES1)and BRASSINAZOLE RESISTANT1 (BZR1).Here we show that BES1 functions as a nucleocytoplasmic signal transmitter, and that its subcellular localization modulates the output intensity of the BR signal.BRASSINOSTEROID INSENSITIVE2 (BIN2)and other group II GLYCOGEN SYNTHASE KINASE 3 GSK3)-like kinases phosphorylate BES1 and induce its nuclear export by regulating its binding affinity with 14-3-3 proteins.We identified twelve putative phosphorylation residues in BES1.Two of these residues, Ser 171 and Thr 175, are critical for interaction with 14-3-3 proteins.The other putative phosphorylation sites in the N-terminal region are required for the BIN2-mediated nuclear export of BES1.Mutations of these motifs result in increased nuclear accumulation of BES1 and enhanced BR responses in transgenic plants.Taken together, our results indicate that the spatial redistribution of BES1 is important for regulation of the BR signaling output.	Brassinosteroids	375-390	bridging integrator 2	Homo sapiens	824-828
20387035-0	2010	Predominant actions of cytosolic BSU1 and nuclear BIN2 regulate subcellular localization of BES1 in brassinosteroid signaling.	Brassinosteroids	100-115	Serine/threonine protein phosphatase family protein	Arabidopsis thaliana	33-37
20387035-0	2010	Predominant actions of cytosolic BSU1 and nuclear BIN2 regulate subcellular localization of BES1 in brassinosteroid signaling.	Brassinosteroids	100-115	Protein kinase superfamily protein	Arabidopsis thaliana	50-54
20387035-0	2010	Predominant actions of cytosolic BSU1 and nuclear BIN2 regulate subcellular localization of BES1 in brassinosteroid signaling.	Brassinosteroids	100-115	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	92-96
20035956-5	2010	Expression of AtEXPA5 was enhanced by exogenously applied brassinosteroids.	Brassinosteroids	58-74	expansin A5	Arabidopsis thaliana	14-21
20035956-6	2010	AtEXPA5 expression was reduced in a brassinosteroid-deficient mutant (det2) and a signaling mutant (bri1-301), while it was increased in bzr1-1D, a dominant mutant of a brassinosteroid transcription factor.	Brassinosteroids	36-51	expansin A5	Arabidopsis thaliana	0-7
20035956-6	2010	AtEXPA5 expression was reduced in a brassinosteroid-deficient mutant (det2) and a signaling mutant (bri1-301), while it was increased in bzr1-1D, a dominant mutant of a brassinosteroid transcription factor.	Brassinosteroids	36-51	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	70-74
20035956-9	2010	These findings indicate that AtEXPA5 is a growth-regulating gene whose expression is controlled by brassinosteroid signaling downstream of BZR1 in A. thaliana.	Brassinosteroids	99-114	expansin A5	Arabidopsis thaliana	29-36
20035956-9	2010	These findings indicate that AtEXPA5 is a growth-regulating gene whose expression is controlled by brassinosteroid signaling downstream of BZR1 in A. thaliana.	Brassinosteroids	99-114	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	139-143
20139304-7	2010	Chromatin immunoprecipitation experiments demonstrated that the presence of AtIWS1 is enriched in transcribed as well as promoter regions of the target genes under BR-induced conditions.	Brassinosteroids	164-166	Transcription elongation factor (TFIIS) family protein	Arabidopsis thaliana	76-82
20004136-2	2010	The mechanisms of ligand-induced kinase activation and downstream signal transduction have been studied for only a few RLK pathways, among which the brassinosteroid (BR) pathway is the best characterized.	Brassinosteroids	149-164	TXK tyrosine kinase	Homo sapiens	119-122
20004136-2	2010	The mechanisms of ligand-induced kinase activation and downstream signal transduction have been studied for only a few RLK pathways, among which the brassinosteroid (BR) pathway is the best characterized.	Brassinosteroids	166-168	TXK tyrosine kinase	Homo sapiens	119-122
19919572-0	2010	The chloroplast protein BPG2 functions in brassinosteroid-mediated post-transcriptional accumulation of chloroplast rRNA.	Brassinosteroids	42-57	P-loop containing nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	24-28
20009022-8	2009	BR increases the RNA levels of ILI1 and PRE1 but represses IBH1 through the transcription factor BZR1.	Brassinosteroids	0-2	basic helix-loop-helix (bHLH) DNA-binding family protein	Arabidopsis thaliana	40-44
20009022-8	2009	BR increases the RNA levels of ILI1 and PRE1 but represses IBH1 through the transcription factor BZR1.	Brassinosteroids	0-2	ILI1 binding bHLH 1	Arabidopsis thaliana	59-63
20009022-8	2009	BR increases the RNA levels of ILI1 and PRE1 but represses IBH1 through the transcription factor BZR1.	Brassinosteroids	0-2	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	97-101
20514242-1	2009	Brassinosteroids (BRs) regulate plant growth and development through a complex signal transduction pathway involving BRASSINOSTEROID INSENSITIVE 1 (BRI1), which is the BR receptor, and its co-receptor BRI1-ASSOCIATED KINASE 1 (BAK1).	Brassinosteroids	0-16	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	148-152
20514242-1	2009	Brassinosteroids (BRs) regulate plant growth and development through a complex signal transduction pathway involving BRASSINOSTEROID INSENSITIVE 1 (BRI1), which is the BR receptor, and its co-receptor BRI1-ASSOCIATED KINASE 1 (BAK1).	Brassinosteroids	0-16	BRI1-associated receptor kinase	Arabidopsis thaliana	201-225
20514242-1	2009	Brassinosteroids (BRs) regulate plant growth and development through a complex signal transduction pathway involving BRASSINOSTEROID INSENSITIVE 1 (BRI1), which is the BR receptor, and its co-receptor BRI1-ASSOCIATED KINASE 1 (BAK1).	Brassinosteroids	0-16	BRI1-associated receptor kinase	Arabidopsis thaliana	227-231
19760261-0	2009	Brassinosteroids promote photosynthesis and growth by enhancing activation of Rubisco and expression of photosynthetic genes in Cucumis sativus.	Brassinosteroids	0-16	ribulose bisphosphate carboxylase small subunit, chloroplastic	Cucumis sativus	78-85
20514242-1	2009	Brassinosteroids (BRs) regulate plant growth and development through a complex signal transduction pathway involving BRASSINOSTEROID INSENSITIVE 1 (BRI1), which is the BR receptor, and its co-receptor BRI1-ASSOCIATED KINASE 1 (BAK1).	Brassinosteroids	18-21	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	148-152
20514242-1	2009	Brassinosteroids (BRs) regulate plant growth and development through a complex signal transduction pathway involving BRASSINOSTEROID INSENSITIVE 1 (BRI1), which is the BR receptor, and its co-receptor BRI1-ASSOCIATED KINASE 1 (BAK1).	Brassinosteroids	18-21	BRI1-associated receptor kinase	Arabidopsis thaliana	201-225
20514242-1	2009	Brassinosteroids (BRs) regulate plant growth and development through a complex signal transduction pathway involving BRASSINOSTEROID INSENSITIVE 1 (BRI1), which is the BR receptor, and its co-receptor BRI1-ASSOCIATED KINASE 1 (BAK1).	Brassinosteroids	18-21	BRI1-associated receptor kinase	Arabidopsis thaliana	227-231
19170933-0	2009	Arabidopsis MYB30 is a direct target of BES1 and cooperates with BES1 to regulate brassinosteroid-induced gene expression.	Brassinosteroids	82-97	myb domain protein 30	Arabidopsis thaliana	12-17
19741050-0	2009	A leaky mutation in DWARF4 reveals an antagonistic role of brassinosteroid in the inhibition of root growth by jasmonate in Arabidopsis.	Brassinosteroids	59-74	Cytochrome P450 superfamily protein	Arabidopsis thaliana	20-26
19741050-5	2009	Physiological analysis showed that an application of exogenous BR eliminated the partial restoration of JA sensitivity by psc1 in coi1-2 background and the JA hypersensitivity of psc1 in wild-type COI1 background.	Brassinosteroids	63-65	Cytochrome P450 superfamily protein	Arabidopsis thaliana	122-126
19741050-5	2009	Physiological analysis showed that an application of exogenous BR eliminated the partial restoration of JA sensitivity by psc1 in coi1-2 background and the JA hypersensitivity of psc1 in wild-type COI1 background.	Brassinosteroids	63-65	RNI-like superfamily protein	Arabidopsis thaliana	130-134
19741050-5	2009	Physiological analysis showed that an application of exogenous BR eliminated the partial restoration of JA sensitivity by psc1 in coi1-2 background and the JA hypersensitivity of psc1 in wild-type COI1 background.	Brassinosteroids	63-65	Cytochrome P450 superfamily protein	Arabidopsis thaliana	179-183
19741050-5	2009	Physiological analysis showed that an application of exogenous BR eliminated the partial restoration of JA sensitivity by psc1 in coi1-2 background and the JA hypersensitivity of psc1 in wild-type COI1 background.	Brassinosteroids	63-65	RNI-like superfamily protein	Arabidopsis thaliana	197-201
19473327-2	2009	One of those genes (AtRALF23) is significantly downregulated by brassinolide (BL) treatment of Arabidopsis seedlings or in mutant seedlings expressing a constitutively active form of BES1, a transcriptional effector of the brassinosteroid signaling pathway.	Brassinosteroids	223-238	rapid alkalinization factor 23	Arabidopsis thaliana	20-28
19473327-2	2009	One of those genes (AtRALF23) is significantly downregulated by brassinolide (BL) treatment of Arabidopsis seedlings or in mutant seedlings expressing a constitutively active form of BES1, a transcriptional effector of the brassinosteroid signaling pathway.	Brassinosteroids	223-238	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	183-187
19532123-0	2009	Membrane steroid-binding protein 1 (MSBP1) negatively regulates brassinosteroid signaling by enhancing the endocytosis of BAK1.	Brassinosteroids	64-79	minisatellite binding protein 1	Homo sapiens	36-41
19532123-0	2009	Membrane steroid-binding protein 1 (MSBP1) negatively regulates brassinosteroid signaling by enhancing the endocytosis of BAK1.	Brassinosteroids	64-79	BCL2 antagonist/killer 1	Homo sapiens	122-126
19748302-3	2009	Since its first description in 2001, several independent groups have discovered BAK1/SERK3 as a component of diverse processes, including brassinosteroid signaling, light responses, cell death, and plant innate immunity.	Brassinosteroids	138-153	BCL2 antagonist/killer 1	Homo sapiens	80-84
19395409-0	2009	BIN2 functions redundantly with other Arabidopsis GSK3-like kinases to regulate brassinosteroid signaling.	Brassinosteroids	80-95	Protein kinase superfamily protein	Arabidopsis thaliana	0-4
19170933-0	2009	Arabidopsis MYB30 is a direct target of BES1 and cooperates with BES1 to regulate brassinosteroid-induced gene expression.	Brassinosteroids	82-97	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	65-69
19277500-1	2009	The plasma membrane-localized BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1) are a well-known receptor pair involved in brassinosteroids (BR) signaling in Arabidposis.	Brassinosteroids	30-45	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	60-64
19000166-5	2009	Mutation of either adaptor or of VH1 results in vein pattern defects and in alterations in response to auxin and brassinosteroids.	Brassinosteroids	113-129	BRI1-like 2	Arabidopsis thaliana	33-36
19526717-5	2009	Our experiments showed that the BR-deficient and BR-insensitive Arabidopsis mutants det2, bri1-5 and bri1-9 were more sensitive to ABA than the wild type (Ws-2), especially the det2 and bri1-9 mutants.	Brassinosteroids	32-34	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	84-88
19526717-5	2009	Our experiments showed that the BR-deficient and BR-insensitive Arabidopsis mutants det2, bri1-5 and bri1-9 were more sensitive to ABA than the wild type (Ws-2), especially the det2 and bri1-9 mutants.	Brassinosteroids	32-34	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	90-107
19526717-5	2009	Our experiments showed that the BR-deficient and BR-insensitive Arabidopsis mutants det2, bri1-5 and bri1-9 were more sensitive to ABA than the wild type (Ws-2), especially the det2 and bri1-9 mutants.	Brassinosteroids	32-34	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	177-181
19526717-5	2009	Our experiments showed that the BR-deficient and BR-insensitive Arabidopsis mutants det2, bri1-5 and bri1-9 were more sensitive to ABA than the wild type (Ws-2), especially the det2 and bri1-9 mutants.	Brassinosteroids	32-34	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	101-107
19526717-5	2009	Our experiments showed that the BR-deficient and BR-insensitive Arabidopsis mutants det2, bri1-5 and bri1-9 were more sensitive to ABA than the wild type (Ws-2), especially the det2 and bri1-9 mutants.	Brassinosteroids	49-51	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	84-88
19526717-5	2009	Our experiments showed that the BR-deficient and BR-insensitive Arabidopsis mutants det2, bri1-5 and bri1-9 were more sensitive to ABA than the wild type (Ws-2), especially the det2 and bri1-9 mutants.	Brassinosteroids	49-51	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	90-107
19526717-5	2009	Our experiments showed that the BR-deficient and BR-insensitive Arabidopsis mutants det2, bri1-5 and bri1-9 were more sensitive to ABA than the wild type (Ws-2), especially the det2 and bri1-9 mutants.	Brassinosteroids	49-51	3-oxo-5-alpha-steroid 4-dehydrogenase family protein	Arabidopsis thaliana	177-181
19526717-5	2009	Our experiments showed that the BR-deficient and BR-insensitive Arabidopsis mutants det2, bri1-5 and bri1-9 were more sensitive to ABA than the wild type (Ws-2), especially the det2 and bri1-9 mutants.	Brassinosteroids	49-51	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	101-107
19277500-1	2009	The plasma membrane-localized BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1) are a well-known receptor pair involved in brassinosteroids (BR) signaling in Arabidposis.	Brassinosteroids	30-45	BRI1-associated receptor kinase	Arabidopsis thaliana	95-99
19277500-1	2009	The plasma membrane-localized BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1) are a well-known receptor pair involved in brassinosteroids (BR) signaling in Arabidposis.	Brassinosteroids	144-160	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	60-64
19277500-1	2009	The plasma membrane-localized BRASSINOSTEROID-INSENSITIVE1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1) are a well-known receptor pair involved in brassinosteroids (BR) signaling in Arabidposis.	Brassinosteroids	144-160	BRI1-associated receptor kinase	Arabidopsis thaliana	95-99
19037657-2	2009	Previous studies demonstrated that BREVIS RADIX (BRX), a protein of unknown biochemical function, maintains a rate-limiting brassinosteroid biosynthesis enzyme expression to keep brassinosteroid biosynthesis above a critical threshold.	Brassinosteroids	124-139	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	35-47
19216774-19	2009	The hypersensitivity of exo roots to BR suggests that EXO plays a diverse role in the control of BR responses in the root.	Brassinosteroids	37-39	Phosphate-responsive 1 family protein	Arabidopsis thaliana	24-27
19216774-19	2009	The hypersensitivity of exo roots to BR suggests that EXO plays a diverse role in the control of BR responses in the root.	Brassinosteroids	37-39	Phosphate-responsive 1 family protein	Arabidopsis thaliana	54-57
19216774-19	2009	The hypersensitivity of exo roots to BR suggests that EXO plays a diverse role in the control of BR responses in the root.	Brassinosteroids	97-99	Phosphate-responsive 1 family protein	Arabidopsis thaliana	24-27
19216774-19	2009	The hypersensitivity of exo roots to BR suggests that EXO plays a diverse role in the control of BR responses in the root.	Brassinosteroids	97-99	Phosphate-responsive 1 family protein	Arabidopsis thaliana	54-57
19118534-4	2009	BAK1 is an LRR-RLK, acting in both brassinosteroid signaling and plant defense responses.	Brassinosteroids	35-50	BRI1-associated receptor kinase	Arabidopsis thaliana	0-4
19118534-4	2009	BAK1 is an LRR-RLK, acting in both brassinosteroid signaling and plant defense responses.	Brassinosteroids	35-50	receptor lectin kinase	Arabidopsis thaliana	15-18
19037657-2	2009	Previous studies demonstrated that BREVIS RADIX (BRX), a protein of unknown biochemical function, maintains a rate-limiting brassinosteroid biosynthesis enzyme expression to keep brassinosteroid biosynthesis above a critical threshold.	Brassinosteroids	179-194	DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein	Arabidopsis thaliana	35-47
19899704-4	2009	Among them there activated by cytokinins, ethylene and brassinosteroids two-component signaling systems involving receptor protein kinases as a sensor, and activated by auxin, gibberellins and jasmonates multicomponent SCF-complexes possessing ubiquitin ligase activity.	Brassinosteroids	55-71	KIT ligand	Homo sapiens	219-222
19124768-0	2009	Tyrosine phosphorylation of the BRI1 receptor kinase emerges as a component of brassinosteroid signaling in Arabidopsis.	Brassinosteroids	79-94	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	32-36
19105183-6	2009	In vivo SERK1 phosphorylation was induced by brassinosteroids.	Brassinosteroids	45-61	somatic embryogenesis receptor-like kinase 1	Arabidopsis thaliana	8-13
18980656-8	2009	Similar to cytokinin, brassinosteroid acts post-transcriptionally by increasing the stability of ACS5 protein, and its effects on ACS5 were additive with those of cytokinin.	Brassinosteroids	22-37	acyl-CoA synthetase long chain family member 5	Homo sapiens	97-101
18980656-8	2009	Similar to cytokinin, brassinosteroid acts post-transcriptionally by increasing the stability of ACS5 protein, and its effects on ACS5 were additive with those of cytokinin.	Brassinosteroids	22-37	acyl-CoA synthetase long chain family member 5	Homo sapiens	130-134
18830673-7	2009	A role of BIM1 in embryonic development not only implicates a function for brassinosteroids in this process, but the interaction of BIM1 with DRN, involved with auxin signalling, represents a possible point of hormonal crosstalk in embryonic patterning and the first example of an interaction of components of the auxin and BR signalling pathways.	Brassinosteroids	75-91	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	10-14