PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 25019556-6 2014 A total of three potential inhibitors of SFRP4 were found, namely cyclothiazide, clopamide and perindopril. Clopamide 81-90 secreted frizzled related protein 4 Homo sapiens 41-46 25019556-8 2014 The findings suggest the possible treatment of diabetes mellitus type 2 by inhibiting the SFRP4 using the inhibitors cyclothiazide, clopamide and perindopril. Clopamide 132-141 secreted frizzled related protein 4 Homo sapiens 90-95 2682268-3 1989 The venoconstrictor response to bradykinin was attenuated after oral administration of both the thiazide-like diuretic clopamide (0.5 mg/kg) or cyclosporine-A (30 mg/kg), and by concomitant local infusion of cyclosporine-A (1-10 micrograms/min). Clopamide 119-128 kininogen 1 Canis lupus familiaris 32-42 2682268-5 1989 infusion of the renin inhibitor H-77 (0.1 mg/kg/h) reversed the inhibition of bradykinin by both clopamide and cyclosporine-A. Clopamide 97-106 renin Canis lupus familiaris 16-21 2682268-5 1989 infusion of the renin inhibitor H-77 (0.1 mg/kg/h) reversed the inhibition of bradykinin by both clopamide and cyclosporine-A. Clopamide 97-106 kininogen 1 Canis lupus familiaris 78-88 6137325-6 1983 Increases in LDL-C caused by chlorthalidone monotherapy were prevented or reversed by the addition of a beta-blocker, usually propranolol or atenolol (n = 18); increases in LDL-C during clopamide monotherapy were reversed after the addition of the beta-blocker pindolol (10 mg/day, n = 17). Clopamide 186-195 component of oligomeric golgi complex 2 Homo sapiens 173-178 5064563-0 1972 [Effect of clopamide and ethacrynic acid on renin secretion in the dog]. Clopamide 11-20 renin Canis lupus familiaris 44-49 7043175-2 1982 Compared to placebo conditions, clopamide monotherapy significantly increased serum low-density lipoprotein cholesterol (LDL-C) by 13% (p less than 0.025). Clopamide 32-41 component of oligomeric golgi complex 2 Homo sapiens 84-119 7043175-2 1982 Compared to placebo conditions, clopamide monotherapy significantly increased serum low-density lipoprotein cholesterol (LDL-C) by 13% (p less than 0.025). Clopamide 32-41 component of oligomeric golgi complex 2 Homo sapiens 121-126 7043175-6 1982 These findings suggest that antihypertensive combination treatment with low doses of clopamide and pindolol is not only effective and well tolerated, but may also avoid the increase in serum LDL-C levels occurring when the thiazide-like diuretic is given alone. Clopamide 85-94 component of oligomeric golgi complex 2 Homo sapiens 191-196 6032108-0 1967 The effects of a substituted sulphamoyl diuretic "clopamide" (DT 327) on insulin release in vitro. Clopamide 50-59 insulin Homo sapiens 73-80