PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 32613412-0 2021 miR-144-3p increases radiosensibility of gastric cancer cells by targeting inhibition of ZEB1. mir-144-3p 0-10 zinc finger E-box binding homeobox 1 Homo sapiens 89-93 32613412-7 2021 It was found that miR-144-3p overexpression or silencing ZEB1 dramatically inhibited the proliferation activity of GC cells under 6 Gy radiation, increased the levels of pro-apoptotic Bax and caspase-3 proteins (p < 0.05) and decreased the anti-apoptotic protein Bcl-2 level (p < 0.05), resulting in an increase in the apoptosis rate of cells. mir-144-3p 18-28 BCL2 associated X, apoptosis regulator Homo sapiens 184-187 32613412-7 2021 It was found that miR-144-3p overexpression or silencing ZEB1 dramatically inhibited the proliferation activity of GC cells under 6 Gy radiation, increased the levels of pro-apoptotic Bax and caspase-3 proteins (p < 0.05) and decreased the anti-apoptotic protein Bcl-2 level (p < 0.05), resulting in an increase in the apoptosis rate of cells. mir-144-3p 18-28 caspase 3 Homo sapiens 192-201 32613412-7 2021 It was found that miR-144-3p overexpression or silencing ZEB1 dramatically inhibited the proliferation activity of GC cells under 6 Gy radiation, increased the levels of pro-apoptotic Bax and caspase-3 proteins (p < 0.05) and decreased the anti-apoptotic protein Bcl-2 level (p < 0.05), resulting in an increase in the apoptosis rate of cells. mir-144-3p 18-28 BCL2 apoptosis regulator Homo sapiens 263-268 32613412-8 2021 miR-144-3p was confirmed to be ZEB1 targeting site by dual luciferase report. mir-144-3p 0-10 zinc finger E-box binding homeobox 1 Homo sapiens 31-35 32613412-10 2021 CONCLUSION: miR-144-3p expression was down-regulated in GC, and it can increase the radiosensitivity of those cells by inhibiting ZEB1 expression. mir-144-3p 12-22 zinc finger E-box binding homeobox 1 Homo sapiens 130-134 33526055-0 2021 MiR-144-3p-mediated dysregulation of EIF4G2 contributes to the development of hepatocellular carcinoma through the ERK pathway. mir-144-3p 0-10 eukaryotic translation initiation factor 4, gamma 2 Mus musculus 37-43 33452670-9 2021 Moreover, by targeting ANO1, miR-144-3p inhibited the activation of NLRP3 inflammasome inflammatory signals in myocardial cells. mir-144-3p 29-39 anoctamin 1, calcium activated chloride channel Mus musculus 23-27 33452670-9 2021 Moreover, by targeting ANO1, miR-144-3p inhibited the activation of NLRP3 inflammasome inflammatory signals in myocardial cells. mir-144-3p 29-39 NLR family, pyrin domain containing 3 Mus musculus 68-73 33452670-10 2021 Collectively, the present study provides a novel insight into the role of miR-144-3p in the inhibition of MIRI, suggesting that the miR-144-3p/ANO1 axis may be a putative therapeutic target in myocardial ischemia. mir-144-3p 74-84 anoctamin 1, calcium activated chloride channel Mus musculus 143-147 33452670-10 2021 Collectively, the present study provides a novel insight into the role of miR-144-3p in the inhibition of MIRI, suggesting that the miR-144-3p/ANO1 axis may be a putative therapeutic target in myocardial ischemia. mir-144-3p 132-142 anoctamin 1, calcium activated chloride channel Mus musculus 143-147 33417281-5 2021 The binding affinity between miR-144-3p and CEP55 was identified using in silico analysis and luciferase activity determination. mir-144-3p 29-39 centrosomal protein 55 Homo sapiens 44-49 33417281-10 2021 CEP55 was targeted by miR-144-3p, which suppressed cervical cancer cell proliferation, invasion and migration and promoted apoptosis via CEP55. mir-144-3p 22-32 centrosomal protein 55 Homo sapiens 0-5 33417281-10 2021 CEP55 was targeted by miR-144-3p, which suppressed cervical cancer cell proliferation, invasion and migration and promoted apoptosis via CEP55. mir-144-3p 22-32 centrosomal protein 55 Homo sapiens 137-142 33417281-13 2021 Collectively, hBMSCs-derived EVs-loaded miR-144-3p impedes the development and progression of cervical cancer through target inhibition of CEP55, therefore providing us with a potential therapeutic target for treating cervical cancer. mir-144-3p 40-50 centrosomal protein 55 Homo sapiens 139-144 33526055-0 2021 MiR-144-3p-mediated dysregulation of EIF4G2 contributes to the development of hepatocellular carcinoma through the ERK pathway. mir-144-3p 0-10 mitogen-activated protein kinase 1 Mus musculus 115-118 33526055-8 2021 The regulation of EIF4G2 by miR-144-3p was performed by luciferase reporter assay and WB. mir-144-3p 28-38 eukaryotic translation initiation factor 4, gamma 2 Mus musculus 18-24 33434322-11 2021 miR-144-3p expression was increased in WT WD mice and human NASH, but reduced in KitW-sh WD mice, and was found to target ALDH1A3. mir-144-3p 0-10 aldehyde dehydrogenase family 1, subfamily A3 Mus musculus 122-129 33381152-0 2020 MiR-144-3p Targets FoxO1 to Reduce Its Regulation of Adiponectin and Promote Adipogenesis. mir-144-3p 0-10 forkhead box O1 Homo sapiens 19-24 33459113-6 2021 The interaction between GAS6-AS2 and miR-144-3p was confirmed by dual-luciferase reporter assay and RNA pull down assay. mir-144-3p 37-47 growth arrest specific 6 Mus musculus 24-28 33459113-6 2021 The interaction between GAS6-AS2 and miR-144-3p was confirmed by dual-luciferase reporter assay and RNA pull down assay. mir-144-3p 37-47 arylsulfatase A Mus musculus 29-32 33459113-12 2021 GAS6-AS2 up-regulated MAPK6 by sponging miR-144-3p in NSCLC tissues and cells. mir-144-3p 40-50 growth arrest specific 6 Mus musculus 0-4 33459113-12 2021 GAS6-AS2 up-regulated MAPK6 by sponging miR-144-3p in NSCLC tissues and cells. mir-144-3p 40-50 arylsulfatase A Mus musculus 5-8 33459113-12 2021 GAS6-AS2 up-regulated MAPK6 by sponging miR-144-3p in NSCLC tissues and cells. mir-144-3p 40-50 mitogen-activated protein kinase 6 Mus musculus 22-27 33381152-0 2020 MiR-144-3p Targets FoxO1 to Reduce Its Regulation of Adiponectin and Promote Adipogenesis. mir-144-3p 0-10 adiponectin, C1Q and collagen domain containing Homo sapiens 53-64 33215418-11 2020 Furthermore, PBX3 was verified to be a target gene of miR-144-3p. mir-144-3p 54-64 PBX homeobox 3 Homo sapiens 13-17 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 35-45 NFE2 like bZIP transcription factor 2 Homo sapiens 160-164 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 35-45 actin alpha 1, skeletal muscle Homo sapiens 166-175 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 35-45 fibronectin 1 Homo sapiens 181-183 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 35-45 NFE2 like bZIP transcription factor 2 Homo sapiens 198-202 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 35-45 snail family transcriptional repressor 1 Homo sapiens 214-219 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 35-45 kelch like ECH associated protein 1 Homo sapiens 253-288 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 35-45 kelch like ECH associated protein 1 Homo sapiens 290-295 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 104-114 NFE2 like bZIP transcription factor 2 Homo sapiens 160-164 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 104-114 actin alpha 1, skeletal muscle Homo sapiens 166-175 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 104-114 fibronectin 1 Homo sapiens 181-183 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 104-114 NFE2 like bZIP transcription factor 2 Homo sapiens 198-202 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 104-114 snail family transcriptional repressor 1 Homo sapiens 214-219 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 104-114 kelch like ECH associated protein 1 Homo sapiens 253-288 33274006-10 2020 In addition, after transfection of miR-144-3p mimics or inhibitor, western blot assay demonstrated that miR-144-3p negatively regulated the expression of total NRF2, alpha-SMA, and FN in cells, and NRF2, NICD, and Snail in the nucleus without affecting Kelch-like ECH-associated protein 1 (KEAP1). mir-144-3p 104-114 kelch like ECH associated protein 1 Homo sapiens 290-295 33274006-11 2020 Finally, we confirmed that transfection of shMALAT1 inhibited NRF2 expression, and its mediated EMT could be rescued by miR-144-3p inhibitor; transfection of pcDNA3.1-MALAT1 promoted NRF2 expression, and its mediated EMT could be reversed by miR-144-3p inhibitor. mir-144-3p 120-130 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 45-51 33274006-11 2020 Finally, we confirmed that transfection of shMALAT1 inhibited NRF2 expression, and its mediated EMT could be rescued by miR-144-3p inhibitor; transfection of pcDNA3.1-MALAT1 promoted NRF2 expression, and its mediated EMT could be reversed by miR-144-3p inhibitor. mir-144-3p 120-130 NFE2 like bZIP transcription factor 2 Homo sapiens 183-187 33274006-12 2020 In summary, we demonstrate that MALAT1 regulates miR-144-3p to facilitate EMT of LECs via the ROS/NRF2/Notch1/Snail pathway. mir-144-3p 49-59 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 32-38 33274006-12 2020 In summary, we demonstrate that MALAT1 regulates miR-144-3p to facilitate EMT of LECs via the ROS/NRF2/Notch1/Snail pathway. mir-144-3p 49-59 NFE2 like bZIP transcription factor 2 Homo sapiens 98-102 33274006-12 2020 In summary, we demonstrate that MALAT1 regulates miR-144-3p to facilitate EMT of LECs via the ROS/NRF2/Notch1/Snail pathway. mir-144-3p 49-59 notch receptor 1 Homo sapiens 103-109 33274006-12 2020 In summary, we demonstrate that MALAT1 regulates miR-144-3p to facilitate EMT of LECs via the ROS/NRF2/Notch1/Snail pathway. mir-144-3p 49-59 snail family transcriptional repressor 1 Homo sapiens 110-115 33116843-0 2020 miR-144-3p Contributes to the Development of Thyroid Tumors Through the PTEN/PI3K/AKT Pathway. mir-144-3p 0-10 phosphatase and tensin homolog Homo sapiens 72-76 33116843-0 2020 miR-144-3p Contributes to the Development of Thyroid Tumors Through the PTEN/PI3K/AKT Pathway. mir-144-3p 0-10 AKT serine/threonine kinase 1 Homo sapiens 82-85 33116843-11 2020 miR-144-3p and PTEN were related to TNM stage, lymph node metastasis and differentiation degree of TC patients. mir-144-3p 0-10 teneurin transmembrane protein 1 Homo sapiens 36-39 33116843-18 2020 Conclusion: Inhibition of miR-144-3p expression can up-regulate PTEN and affect cell proliferation, invasion and apoptosis, which may be a potential therapeutic target for TC. mir-144-3p 26-36 phosphatase and tensin homolog Homo sapiens 64-68 33155199-7 2020 Overexpression of NORAD stimulated proliferative and migratory potentials in ACHN and A498 cells, which were partially abolished by co-overexpression of miR-144-3p. mir-144-3p 153-163 non-coding RNA activated by DNA damage Homo sapiens 18-23 32563146-11 2020 HDAC8 was a direct target of miR-144-3p in NB cells, and miR-144-3p suppressed the progression of NB through down-regulating HDAC8. mir-144-3p 29-39 histone deacetylase 8 Homo sapiens 0-5 32275930-8 2020 Mechanistically, we found that BAG5 modulated FN1 expression at the translational level and promoted invasion via suppression of miR-144-3p, which targeted the 3" untranslational region (UTR) of FN1 transcript. mir-144-3p 129-139 BAG cochaperone 5 Homo sapiens 31-35 32275930-8 2020 Mechanistically, we found that BAG5 modulated FN1 expression at the translational level and promoted invasion via suppression of miR-144-3p, which targeted the 3" untranslational region (UTR) of FN1 transcript. mir-144-3p 129-139 fibronectin 1 Homo sapiens 195-198 33061623-8 2020 Bioinformatics analysis and a luciferase assay demonstrated that EBLN3P directly interacts with miR-144-3p to attenuate miR-144-3p binding to the 3"-untranslated region of DOCK4. mir-144-3p 96-106 endogenous Bornavirus like nucleoprotein 3, pseudogene Homo sapiens 65-70 33061623-8 2020 Bioinformatics analysis and a luciferase assay demonstrated that EBLN3P directly interacts with miR-144-3p to attenuate miR-144-3p binding to the 3"-untranslated region of DOCK4. mir-144-3p 96-106 dedicator of cytokinesis 4 Homo sapiens 172-177 33061623-8 2020 Bioinformatics analysis and a luciferase assay demonstrated that EBLN3P directly interacts with miR-144-3p to attenuate miR-144-3p binding to the 3"-untranslated region of DOCK4. mir-144-3p 120-130 endogenous Bornavirus like nucleoprotein 3, pseudogene Homo sapiens 65-70 33061623-8 2020 Bioinformatics analysis and a luciferase assay demonstrated that EBLN3P directly interacts with miR-144-3p to attenuate miR-144-3p binding to the 3"-untranslated region of DOCK4. mir-144-3p 120-130 dedicator of cytokinesis 4 Homo sapiens 172-177 32917949-0 2020 Overexpression of miR-144-3p alleviates polycystic ovaries syndrome through targeting expression of HSP-70. mir-144-3p 18-28 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 100-106 32917949-12 2020 Furthermore, increased expression of HSP-70 rescued the effects of miR-144-3p on ovarian granulosa cell growth and apoptosis. mir-144-3p 67-77 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 37-43 32917949-14 2020 To sum up, miR-144-3p might function as a novel target for PCOS treatment via targeting HSP-70. mir-144-3p 11-21 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 88-94 32563146-11 2020 HDAC8 was a direct target of miR-144-3p in NB cells, and miR-144-3p suppressed the progression of NB through down-regulating HDAC8. mir-144-3p 57-67 histone deacetylase 8 Homo sapiens 125-130 32355466-10 2020 In addition, KPNA2 was confirmed to be a direct target of miR-144-3p. mir-144-3p 58-68 karyopherin subunit alpha 2 Homo sapiens 13-18 32727087-10 2020 Among the potential protein targets of the most influenced miRNAs, only aquaporin-1, a target of miR-144-3p was downregulated at 24 h. (4) Conclusion: Besides already known miRNAs, septic AKI upregulated miR-762, which may regulate GTP signaling, and miR-144-3p and downregulated its target, aquaporin-1. mir-144-3p 97-107 aquaporin 1 Mus musculus 72-83 32727087-10 2020 Among the potential protein targets of the most influenced miRNAs, only aquaporin-1, a target of miR-144-3p was downregulated at 24 h. (4) Conclusion: Besides already known miRNAs, septic AKI upregulated miR-762, which may regulate GTP signaling, and miR-144-3p and downregulated its target, aquaporin-1. mir-144-3p 97-107 microRNA 762 Mus musculus 204-211 32727087-10 2020 Among the potential protein targets of the most influenced miRNAs, only aquaporin-1, a target of miR-144-3p was downregulated at 24 h. (4) Conclusion: Besides already known miRNAs, septic AKI upregulated miR-762, which may regulate GTP signaling, and miR-144-3p and downregulated its target, aquaporin-1. mir-144-3p 97-107 aquaporin 1 Mus musculus 292-303 32006596-11 2020 Besides, GATA3 was the target of miR-144-3p and GATA3 could be regulated co-operatively by miR-144-3p and Rian. mir-144-3p 33-43 GATA binding protein 3 Mus musculus 9-14 32006596-11 2020 Besides, GATA3 was the target of miR-144-3p and GATA3 could be regulated co-operatively by miR-144-3p and Rian. mir-144-3p 33-43 RNA imprinted and accumulated in nucleus Mus musculus 106-110 32705159-0 2020 miR-144-3p inhibits the proliferation, migration and angiogenesis of multiple myeloma cells by targeting myocyte enhancer factor 2A. mir-144-3p 0-10 myocyte enhancer factor 2A Homo sapiens 105-131 32705159-10 2020 On the whole, the findings of the present study demonstrate that miR-144-3p exerts antitumour effects by downregulating MEF2A to inhibit the proliferation, migration and angiogenesis of MM cells. mir-144-3p 65-75 myocyte enhancer factor 2A Homo sapiens 120-125 32843584-0 2020 Circulating exosomal miR-144-3p inhibits the mobilization of endothelial progenitor cells post myocardial infarction via regulating the MMP9 pathway. mir-144-3p 21-31 matrix metallopeptidase 9 Mus musculus 136-140 32843584-4 2020 RESULTS: DMexo and miR-144-3p mimic-treated MSCs had elevated miR-144-3p levels and decreased MMP9, Ets1 and PLG expression. mir-144-3p 19-29 matrix metallopeptidase 9 Homo sapiens 94-98 32843584-4 2020 RESULTS: DMexo and miR-144-3p mimic-treated MSCs had elevated miR-144-3p levels and decreased MMP9, Ets1 and PLG expression. mir-144-3p 19-29 E26 avian leukemia oncogene 1, 5' domain Mus musculus 100-104 32843584-4 2020 RESULTS: DMexo and miR-144-3p mimic-treated MSCs had elevated miR-144-3p levels and decreased MMP9, Ets1 and PLG expression. mir-144-3p 19-29 plasminogen Mus musculus 109-112 32843584-6 2020 Finally, the luciferase assay confirmed the direct binding between miR-144-3p and Ets1. mir-144-3p 67-77 E26 avian leukemia oncogene 1, 5' domain Mus musculus 82-86 32626925-0 2020 miR-144-3p inhibits tumor cell growth and invasion in oral squamous cell carcinoma through the downregulation of the oncogenic gene, EZH2. mir-144-3p 0-10 enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens 133-137 32626925-7 2020 Moreover, EZH2 expression was increased, and inversely correlated with the miR-144-3p level in OSCC tissues. mir-144-3p 75-85 enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens 10-14 32626925-8 2020 Notably, EZH2 knockdown inhibited cell proliferation, promoted cell apoptosis, and suppressed the invasion and migration of OSCC cells, whereas EZH2 overexpression partially reversed the anticancer effects mediated by miR-144-3p overexpression. mir-144-3p 218-228 enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens 144-148 32626925-9 2020 On the whole, the findings of the present study suggest that miR-144-3p functions as a tumor suppressor by targeting the EZH2 oncogene, and may thus be considered as a potential diagnostic and therapeutic target for OSCC. mir-144-3p 61-71 enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens 121-125 32505917-13 2020 In MLE-12 cells, the overexpression of miR-144-3p elicited the same effect as NNK regarding the expression of lung cancer biomarker CK19; the silencing of miR-144-3p reversed the effect of NNK on cell cycle distribution and apoptosis. mir-144-3p 39-49 keratin 19 Mus musculus 132-136 32550890-13 2020 The pro-metastatic effect of FABP5 was reduced by miR-144-3p. mir-144-3p 50-60 fatty acid binding protein 5, epidermal Mus musculus 29-34 32550890-16 2020 Moreover, the expression and biological function of FABP5 can be regulated by miR-144-3p in hypoxia. mir-144-3p 78-88 fatty acid binding protein 5, epidermal Mus musculus 52-57 32355466-12 2020 Conclusion: LINC00461 promoted the expression of KPNA2 by competitively binding to miR-144-3p, thereby promoting the invasion and migration of breast cancer cells. mir-144-3p 83-93 long intergenic non-protein coding RNA 461 Homo sapiens 12-21 32355466-12 2020 Conclusion: LINC00461 promoted the expression of KPNA2 by competitively binding to miR-144-3p, thereby promoting the invasion and migration of breast cancer cells. mir-144-3p 83-93 karyopherin subunit alpha 2 Homo sapiens 49-54 33772768-0 2021 miR-144-3p ameliorates the progression of osteoarthritis by targeting IL-1beta: Potential therapeutic implications. mir-144-3p 0-10 interleukin 1 alpha Rattus norvegicus 70-78 30499593-10 2019 The inhibition of miR-144-3p attenuated the inhibitory effect of hemin on lipoxin A4 receptor (ALX)/formyl peptide receptor 2 (FPR2) protein expression (p < 0.05). mir-144-3p 18-28 formyl peptide receptor 3 Mus musculus 74-93 30499593-10 2019 The inhibition of miR-144-3p attenuated the inhibitory effect of hemin on lipoxin A4 receptor (ALX)/formyl peptide receptor 2 (FPR2) protein expression (p < 0.05). mir-144-3p 18-28 formyl peptide receptor 3 Mus musculus 95-98 30499593-10 2019 The inhibition of miR-144-3p attenuated the inhibitory effect of hemin on lipoxin A4 receptor (ALX)/formyl peptide receptor 2 (FPR2) protein expression (p < 0.05). mir-144-3p 18-28 formyl peptide receptor 2 Mus musculus 100-125 30499593-10 2019 The inhibition of miR-144-3p attenuated the inhibitory effect of hemin on lipoxin A4 receptor (ALX)/formyl peptide receptor 2 (FPR2) protein expression (p < 0.05). mir-144-3p 18-28 formyl peptide receptor 2 Mus musculus 127-131 30720179-10 2019 CONCLUSIONS: Taken together, these results demonstrated the tumor suppressive role of miR-144-3p in NB and may advance the understanding of the underlying mechanisms of miR-144-3p and HOXA7 in NB. mir-144-3p 86-96 homeobox A7 Homo sapiens 184-189 30536309-0 2018 MiR-144-3p inhibits the proliferation and metastasis of pediatric Wilms" tumor cells by regulating Girdin. mir-144-3p 0-10 coiled-coil domain containing 88A Homo sapiens 99-105 30536309-9 2018 The interaction between miR-144-3p and Girdin was further verified by dual Luciferase reporter gene assay and Western blot. mir-144-3p 24-34 coiled-coil domain containing 88A Homo sapiens 39-45 30536309-12 2018 CONCLUSIONS: MiR-144-3p, which was up-regulated in pediatric WT, might inhibit the proliferation and metastasis of the cells by directly targeting Girdin. mir-144-3p 13-23 coiled-coil domain containing 88A Homo sapiens 147-153 33772768-5 2021 In this study, we observed a negative correlation between miR-144-3p and IL-1beta expression in OA. mir-144-3p 58-68 interleukin 1 alpha Rattus norvegicus 73-81 33772768-6 2021 miR-144-3p mimic transfection of OA synovial fibroblasts downregulated levels of IL-1beta expression, while blocking the MAPK, PI3K/Akt, and NF-kappaB signaling pathways relating to IL-1beta production, and effectively increased miR-144-3p expression in OASFs. mir-144-3p 0-10 interleukin 1 alpha Rattus norvegicus 81-89 33772768-6 2021 miR-144-3p mimic transfection of OA synovial fibroblasts downregulated levels of IL-1beta expression, while blocking the MAPK, PI3K/Akt, and NF-kappaB signaling pathways relating to IL-1beta production, and effectively increased miR-144-3p expression in OASFs. mir-144-3p 0-10 AKT serine/threonine kinase 1 Rattus norvegicus 132-135 33772768-6 2021 miR-144-3p mimic transfection of OA synovial fibroblasts downregulated levels of IL-1beta expression, while blocking the MAPK, PI3K/Akt, and NF-kappaB signaling pathways relating to IL-1beta production, and effectively increased miR-144-3p expression in OASFs. mir-144-3p 0-10 interleukin 1 alpha Rattus norvegicus 182-190 34934452-5 2022 These data indicated that miR-144-3p plays a role in inhibiting BMSC osteogenic differentiation and that GATA4 inhibits osteogenic differentiation by targeting miR-144-3p expression. mir-144-3p 26-36 GATA binding protein 4 Rattus norvegicus 105-110 34730058-9 2022 The level of miR-144-3p in N1511 cells was upregulated by IL-1beta. mir-144-3p 13-23 interleukin 1 alpha Homo sapiens 58-66 34730058-10 2022 MiR-144-3p knockdown inhibited IL-1beta-induced pyroptosis in N1511 cells, and the expressions of NOD-like receptor family pyrin domain containing 3 (NLRP3), Cleaved caspase-1, Gasdermin D (GSDMD), and Cleaved caspase-3 in IL-1beta-stimulated N1511 cells were increased. mir-144-3p 0-10 interleukin 1 alpha Homo sapiens 31-39 34730058-10 2022 MiR-144-3p knockdown inhibited IL-1beta-induced pyroptosis in N1511 cells, and the expressions of NOD-like receptor family pyrin domain containing 3 (NLRP3), Cleaved caspase-1, Gasdermin D (GSDMD), and Cleaved caspase-3 in IL-1beta-stimulated N1511 cells were increased. mir-144-3p 0-10 NLR family pyrin domain containing 3 Homo sapiens 150-155 34730058-10 2022 MiR-144-3p knockdown inhibited IL-1beta-induced pyroptosis in N1511 cells, and the expressions of NOD-like receptor family pyrin domain containing 3 (NLRP3), Cleaved caspase-1, Gasdermin D (GSDMD), and Cleaved caspase-3 in IL-1beta-stimulated N1511 cells were increased. mir-144-3p 0-10 gasdermin D Homo sapiens 177-188 34730058-10 2022 MiR-144-3p knockdown inhibited IL-1beta-induced pyroptosis in N1511 cells, and the expressions of NOD-like receptor family pyrin domain containing 3 (NLRP3), Cleaved caspase-1, Gasdermin D (GSDMD), and Cleaved caspase-3 in IL-1beta-stimulated N1511 cells were increased. mir-144-3p 0-10 gasdermin D Homo sapiens 190-195 34730058-10 2022 MiR-144-3p knockdown inhibited IL-1beta-induced pyroptosis in N1511 cells, and the expressions of NOD-like receptor family pyrin domain containing 3 (NLRP3), Cleaved caspase-1, Gasdermin D (GSDMD), and Cleaved caspase-3 in IL-1beta-stimulated N1511 cells were increased. mir-144-3p 0-10 interleukin 1 alpha Homo sapiens 223-231 34730058-11 2022 The levels of inflammatory cytokines in N1511 cells were increased by IL-1beta, which were restored by miR-144-3p knockdown. mir-144-3p 103-113 interleukin 1 alpha Homo sapiens 70-78 34730058-12 2022 MiR-144-3p knockdown abolished IL-1beta-induced inactivation of putative kinase 1 (PINK1)/Parkin RBR E3 ubiquitin-protein (Parkin) signalling. mir-144-3p 0-10 PTEN induced kinase 1 Homo sapiens 83-88 34934452-5 2022 These data indicated that miR-144-3p plays a role in inhibiting BMSC osteogenic differentiation and that GATA4 inhibits osteogenic differentiation by targeting miR-144-3p expression. mir-144-3p 160-170 GATA binding protein 4 Rattus norvegicus 105-110 34800749-9 2022 In conclusion, Se deficiency can induce apoptosis and cell cycle arrest of bursa of Fabricius in Broilers by up regulating miR-144-3p targeting STC1 and activating PI3K/AKT pathway, leading to injury of bursa of Fabricius in broilers. mir-144-3p 123-133 stanniocalcin 1 Homo sapiens 144-148 34910830-9 2022 Upregulation of NR2F2 reversed the inhibitory effect of miR-144-3p on surviving PDLCs after LPS treatment. mir-144-3p 56-66 nuclear receptor subfamily 2 group F member 2 Homo sapiens 16-21 34192826-11 2021 Furthermore, the dual-luciferase reporter assay confirmed that miR-144-3p targeted YAP1, and overexpressing YAP1 partially weakened the inhibitive effects of miR-144-3p on NB cells. mir-144-3p 158-168 microRNA 144 Homo sapiens 63-70 34850093-9 2021 Interaction of miR-144-3p and BMP2 was verified by dual luciferase assay. mir-144-3p 15-25 bone morphogenetic protein 2 Rattus norvegicus 30-34 34850093-10 2021 RESULTS: MiR-144-3p was dramatically increased in IL-1beta induced N1511 cells. mir-144-3p 9-19 interleukin 1 alpha Rattus norvegicus 50-58 34850093-11 2021 MiR-144-3p depletion elevated cell viability, suppressed apoptosis, pro-inflammatory cytokine releasing, and extracellular matrix loss in IL-1beta induced N1511 cells. mir-144-3p 0-10 interleukin 1 alpha Rattus norvegicus 138-146 34850093-12 2021 Moreover, miR-144-3p targeted BMP2 to modulate its expression negatively. mir-144-3p 10-20 bone morphogenetic protein 2 Rattus norvegicus 30-34 34850093-15 2021 CONCLUSION: Collectively, miR-144-3p could aggravate chondrocytes injury inflammatory response in RA via BMP2/PI3K/Akt axis. mir-144-3p 26-36 bone morphogenetic protein 2 Rattus norvegicus 105-109 34850093-15 2021 CONCLUSION: Collectively, miR-144-3p could aggravate chondrocytes injury inflammatory response in RA via BMP2/PI3K/Akt axis. mir-144-3p 26-36 AKT serine/threonine kinase 1 Rattus norvegicus 115-118 34674715-9 2021 Among them, miR-144-3p directly mediated GABA synthesis and release by targeting Gad1 and VGAT, and miR-495 negatively regulated BDNF expression. mir-144-3p 12-22 solute carrier family 32 member 1 Rattus norvegicus 90-94 34657624-0 2021 MiR-144-3p inhibits gastric cancer progression and stemness via directly targeting GLI2 involved in hedgehog pathway. mir-144-3p 0-10 GLI family zinc finger 2 Homo sapiens 83-87 34657624-13 2021 Meanwhile, miR-144-3p was downregulated and negatively correlated with GLI2 in GC. mir-144-3p 11-21 GLI family zinc finger 2 Homo sapiens 71-75 34657624-16 2021 Enhanced miR-144-3p expression inhibited tumorsphere formation and CD44 expression of GCSCs. mir-144-3p 9-19 CD44 molecule (Indian blood group) Homo sapiens 67-71 34657624-17 2021 Restoration of GLI2 expression partly reversed the suppressive effect of miR-144-3p. mir-144-3p 73-83 GLI family zinc finger 2 Homo sapiens 15-19 34435195-0 2021 Inhibition of miR-144-3p exacerbates non-small cell lung cancer progression by targeting CEP55. mir-144-3p 14-24 centrosomal protein 55 Homo sapiens 89-94 34435195-7 2021 Dual-luciferase reporter assay revealed that miR-144-3p modulated malignant properties of cancer cells by targeting CEP55. mir-144-3p 45-55 centrosomal protein 55 Homo sapiens 116-121 34435195-8 2021 Overexpression of CEP55 partially blocked the inhibitory effect of miR-144-3p on proliferation and migration of A549 cells and induced apoptosis of A549 cells. mir-144-3p 67-77 centrosomal protein 55 Homo sapiens 18-23 34435195-9 2021 CEP55 knockdown modulated the increase in proliferation and migration and the decrease in apoptosis of H460 cells following miR-144-3p inhibition. mir-144-3p 124-134 centrosomal protein 55 Homo sapiens 0-5 34435195-10 2021 These findings demonstrated that miR-144-3p suppresses NSCLC development by inhibiting CEP55 expression. mir-144-3p 33-43 centrosomal protein 55 Homo sapiens 87-92 34192826-11 2021 Furthermore, the dual-luciferase reporter assay confirmed that miR-144-3p targeted YAP1, and overexpressing YAP1 partially weakened the inhibitive effects of miR-144-3p on NB cells. mir-144-3p 158-168 Yes1 associated transcriptional regulator Homo sapiens 83-87 34192826-11 2021 Furthermore, the dual-luciferase reporter assay confirmed that miR-144-3p targeted YAP1, and overexpressing YAP1 partially weakened the inhibitive effects of miR-144-3p on NB cells. mir-144-3p 158-168 Yes1 associated transcriptional regulator Homo sapiens 108-112 34547172-6 2021 This study confirmed that the level of miR-144-3p was significantly reduced following renal I/R injury and H/R injury in vitro, and miR-144-3p was determined to target Nrf2 and inhibit its expression. mir-144-3p 39-49 NFE2 like bZIP transcription factor 2 Homo sapiens 168-172 34547172-6 2021 This study confirmed that the level of miR-144-3p was significantly reduced following renal I/R injury and H/R injury in vitro, and miR-144-3p was determined to target Nrf2 and inhibit its expression. mir-144-3p 132-142 NFE2 like bZIP transcription factor 2 Homo sapiens 168-172 34547172-7 2021 In addition, lncRNA TUG1 can reduce the inhibitory effect of miR-144-3p on Nrf2 by sponging miR-144-3p. mir-144-3p 61-71 taurine up-regulated 1 Homo sapiens 20-24 34547172-7 2021 In addition, lncRNA TUG1 can reduce the inhibitory effect of miR-144-3p on Nrf2 by sponging miR-144-3p. mir-144-3p 61-71 NFE2 like bZIP transcription factor 2 Homo sapiens 75-79 34547172-7 2021 In addition, lncRNA TUG1 can reduce the inhibitory effect of miR-144-3p on Nrf2 by sponging miR-144-3p. mir-144-3p 92-102 taurine up-regulated 1 Homo sapiens 20-24 34547172-7 2021 In addition, lncRNA TUG1 can reduce the inhibitory effect of miR-144-3p on Nrf2 by sponging miR-144-3p. mir-144-3p 92-102 NFE2 like bZIP transcription factor 2 Homo sapiens 75-79 35568918-0 2022 MiR-144-3p inhibits the proliferation and metastasis of lung cancer A549 cells via targeting HGF. mir-144-3p 0-10 hepatocyte growth factor Mus musculus 93-96 34504602-0 2021 Upregulation of miR-144-3p expression attenuates glioma cell viability and invasion by targeting BCL6. mir-144-3p 16-26 BCL6 transcription repressor Homo sapiens 97-101 34504602-7 2021 Luciferase reporter assay was used to assess the association between miR-144-3p and BCL6 and a tumor xenograft model was established for assess tumor growth. mir-144-3p 69-79 BCL6 transcription repressor Homo sapiens 84-88 34542064-13 2022 We identified pyruvate dehydrogenase kinase 4 (PDK4), which is a glucose metabolism key enzyme, was directly targeted by miR-144-3p in CRC cells. mir-144-3p 121-131 pyruvate dehydrogenase kinase 4 Homo sapiens 14-45 34542064-13 2022 We identified pyruvate dehydrogenase kinase 4 (PDK4), which is a glucose metabolism key enzyme, was directly targeted by miR-144-3p in CRC cells. mir-144-3p 121-131 pyruvate dehydrogenase kinase 4 Homo sapiens 47-51 34542064-15 2022 Finally, restoration of miR-144-3p in HCG11-overexpressing DLD-1 5-FU resistant cells successfully overcame the HCG11-faciliated 5-FU resistance via targeting PDK4. mir-144-3p 24-34 HLA complex group 11 Homo sapiens 38-43 34542064-15 2022 Finally, restoration of miR-144-3p in HCG11-overexpressing DLD-1 5-FU resistant cells successfully overcame the HCG11-faciliated 5-FU resistance via targeting PDK4. mir-144-3p 24-34 HLA complex group 11 Homo sapiens 112-117 34542064-15 2022 Finally, restoration of miR-144-3p in HCG11-overexpressing DLD-1 5-FU resistant cells successfully overcame the HCG11-faciliated 5-FU resistance via targeting PDK4. mir-144-3p 24-34 pyruvate dehydrogenase kinase 4 Homo sapiens 159-163 34364983-9 2022 Enhanced miR-144-3p diminished SMC proliferation by binding to the EZH2 3"-untranslated region and thereby inhibiting EZH2 expression. mir-144-3p 9-19 enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens 67-71 34364983-9 2022 Enhanced miR-144-3p diminished SMC proliferation by binding to the EZH2 3"-untranslated region and thereby inhibiting EZH2 expression. mir-144-3p 9-19 enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens 118-122 34364983-10 2022 In addition, EZH2 was highly enriched in the promoter region of p21, and knockdown of p21 expression could rescue the effect of miR-144-3p on SMC proliferation and apoptosis. mir-144-3p 128-138 enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens 13-17 34364983-10 2022 In addition, EZH2 was highly enriched in the promoter region of p21, and knockdown of p21 expression could rescue the effect of miR-144-3p on SMC proliferation and apoptosis. mir-144-3p 128-138 H3 histone pseudogene 16 Homo sapiens 64-67 34364983-10 2022 In addition, EZH2 was highly enriched in the promoter region of p21, and knockdown of p21 expression could rescue the effect of miR-144-3p on SMC proliferation and apoptosis. mir-144-3p 128-138 H3 histone pseudogene 16 Homo sapiens 86-89 34326893-10 2021 In conclusion, our study confirmed the loss or downregulation of miR-144-3p in LSCC, which might contribute to the LSCC tumorigenesis and progression via regulation of the 12 novel targets, such as IL24, ITGA6, and CEP55. mir-144-3p 65-75 interleukin 24 Homo sapiens 198-202 34326893-10 2021 In conclusion, our study confirmed the loss or downregulation of miR-144-3p in LSCC, which might contribute to the LSCC tumorigenesis and progression via regulation of the 12 novel targets, such as IL24, ITGA6, and CEP55. mir-144-3p 65-75 integrin subunit alpha 6 Homo sapiens 204-209 34326893-10 2021 In conclusion, our study confirmed the loss or downregulation of miR-144-3p in LSCC, which might contribute to the LSCC tumorigenesis and progression via regulation of the 12 novel targets, such as IL24, ITGA6, and CEP55. mir-144-3p 65-75 centrosomal protein 55 Homo sapiens 215-220 34226299-0 2021 miR-144-3p inhibited the growth, metastasis and epithelial-mesenchymal transition of colorectal adenocarcinoma by targeting ZEB1/2. mir-144-3p 0-10 zinc finger E-box binding homeobox 1 Homo sapiens 124-130 34226299-9 2021 Finally, we confirmed that ZEB1 and ZEB2 down-regulation collaboratively mediated the inhibitory effect of miR-144-3p on proliferation, invasion and EMT of CRA cells. mir-144-3p 107-117 zinc finger E-box binding homeobox 1 Homo sapiens 27-31 34226299-9 2021 Finally, we confirmed that ZEB1 and ZEB2 down-regulation collaboratively mediated the inhibitory effect of miR-144-3p on proliferation, invasion and EMT of CRA cells. mir-144-3p 107-117 zinc finger E-box binding homeobox 2 Homo sapiens 36-40 34226299-10 2021 In conclusion, our study provided evidence that miR-144-3p could inhibit CRA cell proliferation, invasion and EMT by targeting ZEB1/2. mir-144-3p 48-58 zinc finger E-box binding homeobox 1 Homo sapiens 127-133 34164962-9 2021 MiR-144-3p could bind to LINC00662, and the promoting effect of LINC00662 overexpression was counteracted by miR-144-3p mimic. mir-144-3p 0-10 long intergenic non-protein coding RNA 662 Homo sapiens 25-34 34164962-9 2021 MiR-144-3p could bind to LINC00662, and the promoting effect of LINC00662 overexpression was counteracted by miR-144-3p mimic. mir-144-3p 0-10 long intergenic non-protein coding RNA 662 Homo sapiens 64-73 34164962-9 2021 MiR-144-3p could bind to LINC00662, and the promoting effect of LINC00662 overexpression was counteracted by miR-144-3p mimic. mir-144-3p 109-119 long intergenic non-protein coding RNA 662 Homo sapiens 25-34 34164962-9 2021 MiR-144-3p could bind to LINC00662, and the promoting effect of LINC00662 overexpression was counteracted by miR-144-3p mimic. mir-144-3p 109-119 long intergenic non-protein coding RNA 662 Homo sapiens 64-73 35568918-9 2022 HGF was a direct target of miR-144-3p. mir-144-3p 27-37 hepatocyte growth factor Mus musculus 0-3 35568918-11 2022 Overexpression miR-144-3p suppressed A549 and NCI-H1299 cell proliferation and metastasis, whereas this was reversed by HGF. mir-144-3p 15-25 hepatocyte growth factor Homo sapiens 120-123 35568918-13 2022 CONCLUSIONS: This study reveals miR-144-3p/HGF axis may be involved in the suppression of lung cancer cellular proliferation and development, and miR-144-3p may function as a potential therapeutic target in lung cancer treatment in the future. mir-144-3p 32-42 hepatocyte growth factor Mus musculus 43-46 35568918-13 2022 CONCLUSIONS: This study reveals miR-144-3p/HGF axis may be involved in the suppression of lung cancer cellular proliferation and development, and miR-144-3p may function as a potential therapeutic target in lung cancer treatment in the future. mir-144-3p 146-156 hepatocyte growth factor Mus musculus 43-46 35551606-12 2022 LINC00662 up-regulates SOX2 expression by competitively binding to miR-144-3p, thereby modulating BC cell progression. mir-144-3p 67-77 long intergenic non-protein coding RNA 662 Homo sapiens 0-9 35551606-12 2022 LINC00662 up-regulates SOX2 expression by competitively binding to miR-144-3p, thereby modulating BC cell progression. mir-144-3p 67-77 SRY-box transcription factor 2 Homo sapiens 23-27 35592654-0 2022 Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch. mir-144-3p 10-20 phosphatase and tensin homolog Rattus norvegicus 44-48 35592654-14 2022 ALP staining results revealed that the miR-144-3p mimic group (si-PTEN group) showed significantly higher osteogenic differentiation ability and ALP activity of MSC than the tension group and mimic-NC group (si-NC group). mir-144-3p 39-49 phosphatase and tensin homolog Rattus norvegicus 66-70 35592654-15 2022 Conclusion: miR-144-3p may inhibit apoptosis and promote proliferation and osteogenic differentiation of BMSCs under tension by targeting and regulating PTEN. mir-144-3p 12-22 phosphatase and tensin homolog Rattus norvegicus 153-157 35507744-0 2022 Extracellular vesicles from bone marrow mesenchymal stem cells inhibit apoptosis and autophagy of ischemia-hypoxia cardiomyocyte line in vitro by carrying miR-144-3p to inhibit ROCK1. mir-144-3p 155-165 Rho associated coiled-coil containing protein kinase 1 Homo sapiens 177-182 35624329-9 2022 In addition, miR-144-3p was significantly reduced in the oxygen and glucose deprivation/reperfusion cell model, and miR-144-3p could directly target PTEN to regulate its expression. mir-144-3p 13-23 phosphatase and tensin homolog Homo sapiens 149-153 35624329-9 2022 In addition, miR-144-3p was significantly reduced in the oxygen and glucose deprivation/reperfusion cell model, and miR-144-3p could directly target PTEN to regulate its expression. mir-144-3p 116-126 phosphatase and tensin homolog Homo sapiens 149-153 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 58-68 phosphatase and tensin homolog Homo sapiens 194-198 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 58-68 AKT serine/threonine kinase 1 Homo sapiens 199-202 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 58-68 NFE2 like bZIP transcription factor 2 Homo sapiens 203-207 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 58-68 phosphatase and tensin homolog Homo sapiens 306-310 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 58-68 AKT serine/threonine kinase 1 Homo sapiens 311-314 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 58-68 NFE2 like bZIP transcription factor 2 Homo sapiens 315-319 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 240-250 phosphatase and tensin homolog Homo sapiens 194-198 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 240-250 AKT serine/threonine kinase 1 Homo sapiens 199-202 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 240-250 NFE2 like bZIP transcription factor 2 Homo sapiens 203-207 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 240-250 phosphatase and tensin homolog Homo sapiens 306-310 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 240-250 AKT serine/threonine kinase 1 Homo sapiens 311-314 35624329-10 2022 Additional studies showed that changing the expression of miR-144-3p in BMSC-exos significantly affected the regulation of intestinal injury, intestinal cell apoptosis, oxidative stress and the PTEN/Akt/Nrf2 pathway in I/R, suggesting that miR-144-3p in BMSC-exos plays an important role in regulating the PTEN/Akt/Nrf2 during intestinal I/R. mir-144-3p 240-250 NFE2 like bZIP transcription factor 2 Homo sapiens 315-319 35501800-10 2022 Moreover, ZBTB7A was a target of miR-144-3p, which decreased ZBTB7A expression in BC. mir-144-3p 33-43 zinc finger and BTB domain containing 7A Homo sapiens 10-16 35501800-10 2022 Moreover, ZBTB7A was a target of miR-144-3p, which decreased ZBTB7A expression in BC. mir-144-3p 33-43 zinc finger and BTB domain containing 7A Homo sapiens 61-67 35507744-12 2022 BMSCs-EVs-derived miR-144-3p targeted ROCK1 to radically activate the PI3K/AKT/mTOR pathway. mir-144-3p 18-28 Rho associated coiled-coil containing protein kinase 1 Homo sapiens 38-43 35507744-12 2022 BMSCs-EVs-derived miR-144-3p targeted ROCK1 to radically activate the PI3K/AKT/mTOR pathway. mir-144-3p 18-28 AKT serine/threonine kinase 1 Homo sapiens 75-78 35507744-12 2022 BMSCs-EVs-derived miR-144-3p targeted ROCK1 to radically activate the PI3K/AKT/mTOR pathway. mir-144-3p 18-28 mechanistic target of rapamycin kinase Homo sapiens 79-83 35507744-13 2022 Overall, our study elicited that BMSCs-EVs carried miR-144-3p into the I/H cardiomyocyte line to target ROCK1 and stimulate the PI3K/AKT/mTOR pathway, thus inhibiting I/H-induced cardiomyocyte line apoptosis and autophagy. mir-144-3p 51-61 Rho associated coiled-coil containing protein kinase 1 Homo sapiens 104-109 35507744-13 2022 Overall, our study elicited that BMSCs-EVs carried miR-144-3p into the I/H cardiomyocyte line to target ROCK1 and stimulate the PI3K/AKT/mTOR pathway, thus inhibiting I/H-induced cardiomyocyte line apoptosis and autophagy. mir-144-3p 51-61 AKT serine/threonine kinase 1 Homo sapiens 133-136 35507744-13 2022 Overall, our study elicited that BMSCs-EVs carried miR-144-3p into the I/H cardiomyocyte line to target ROCK1 and stimulate the PI3K/AKT/mTOR pathway, thus inhibiting I/H-induced cardiomyocyte line apoptosis and autophagy. mir-144-3p 51-61 mechanistic target of rapamycin kinase Homo sapiens 137-141 35434335-11 2022 Mechanically, circLPAR3 sponged miR-144-3p to prohibit the inhibiting effect of miR-144-3p on LPCAT1, thus promoting OSCC progression. mir-144-3p 32-42 lysophosphatidylcholine acyltransferase 1 Homo sapiens 94-100 35276076-0 2022 miR-144-3p Functions as a Tumor Suppressor in Endometrial Cancer by Targeting PRR11. mir-144-3p 0-10 proline rich 11 Homo sapiens 78-83 35276076-6 2022 Gain-of-function and loss-of-function cell models were established, and the biological functions of miR-144-3p and PRR11 in EC cells were investigated by CCK-8 assay, annexin V/PI double staining assay, Transwell assay, respectively. mir-144-3p 100-110 annexin A5 Homo sapiens 167-176 35276076-9 2022 Functionally, miR-144-3p mimics greatly restrained the proliferation, migration and invasion of EC cells, but enhanced the apoptosis of cancer cells; conversely, PRR11 promoted the proliferation, migration and invasion of EC cells, while reduced the apoptotic rates. mir-144-3p 14-24 proline rich 11 Homo sapiens 162-167 35276076-11 2022 Moreover, rescue experiments demonstrated that PRR11 overexpression partially reversed the inhibitory function of miR-144-3p on the malignant phenotypes of EC cells. mir-144-3p 114-124 proline rich 11 Homo sapiens 47-52 35276076-12 2022 CONCLUSIONS: MiR-144-3p may function as tumor suppressor in EC via regulating PRR11 expression. mir-144-3p 13-23 proline rich 11 Homo sapiens 78-83 35624329-6 2022 Furthermore, the relationship between miR-144-3p and PTEN was confirmed by a dual-luciferase reporter assay. mir-144-3p 38-48 phosphatase and tensin homolog Homo sapiens 53-57 35300565-7 2022 MTT assay, wound healing assay, EdU assay, and Transwell assay were utilized to verify the impact of miR-144-3p modulation on HCC proliferation and EMT via ARRDC1. mir-144-3p 101-111 arrestin domain containing 1 Homo sapiens 156-162 35434335-11 2022 Mechanically, circLPAR3 sponged miR-144-3p to prohibit the inhibiting effect of miR-144-3p on LPCAT1, thus promoting OSCC progression. mir-144-3p 80-90 lysophosphatidylcholine acyltransferase 1 Homo sapiens 94-100 34989308-7 2022 The interaction between miR-144-3p and ATP1B2 was predicted and assessed by using bioinformatic methods and a luciferase reporter gene assay, respectively.Results MiR-144-3p expression was elevated in the schizophrenic rat hippocampus. mir-144-3p 24-34 ATPase Na+/K+ transporting subunit beta 2 Rattus norvegicus 39-45 35402178-11 2022 The B4GALT1-AS1 and miR-144-3p interaction was shown by using rescue experiments. mir-144-3p 20-30 beta-1,4-galactosyltransferase 1 Homo sapiens 4-11 35402178-13 2022 Conclusions: In summary, the progression of NSCLC was facilitated by lncRNA B4GALT1-AS1 via interaction with miR-144-3p and positive regulation of ZEB1 expression. mir-144-3p 109-119 beta-1,4-galactosyltransferase 1 Homo sapiens 76-83 35402178-13 2022 Conclusions: In summary, the progression of NSCLC was facilitated by lncRNA B4GALT1-AS1 via interaction with miR-144-3p and positive regulation of ZEB1 expression. mir-144-3p 109-119 prostaglandin D2 receptor Homo sapiens 84-87 35069905-6 2022 We further confirmed that TOP2A is a direct target of miR-144-3p whose overexpressing can partially reverse the effect of TOP2A in HCC cells. mir-144-3p 54-64 DNA topoisomerase II alpha Homo sapiens 26-31 35069905-6 2022 We further confirmed that TOP2A is a direct target of miR-144-3p whose overexpressing can partially reverse the effect of TOP2A in HCC cells. mir-144-3p 54-64 DNA topoisomerase II alpha Homo sapiens 122-127 35197108-16 2022 miR-144-3p was enriched in TDSC-Exos and promoted tenocyte proliferation and migration via targeting AT-rich interactive domain 1A (ARID1A). mir-144-3p 0-10 AT-rich interaction domain 1A Rattus norvegicus 101-130 35197108-16 2022 miR-144-3p was enriched in TDSC-Exos and promoted tenocyte proliferation and migration via targeting AT-rich interactive domain 1A (ARID1A). mir-144-3p 0-10 AT-rich interaction domain 1A Rattus norvegicus 132-138 34989308-7 2022 The interaction between miR-144-3p and ATP1B2 was predicted and assessed by using bioinformatic methods and a luciferase reporter gene assay, respectively.Results MiR-144-3p expression was elevated in the schizophrenic rat hippocampus. mir-144-3p 163-173 ATPase Na+/K+ transporting subunit beta 2 Rattus norvegicus 39-45 34989308-9 2022 Additionally, miR-144-3p can directly bind with ATP1B2. mir-144-3p 14-24 ATPase Na+/K+ transporting subunit beta 2 Homo sapiens 48-54 33995991-7 2021 The binding profile of NEAT1 to miR-144-3p was evaluated via a combination approach of luciferase activity assay, RNA immunoprecipitation, and RNA pull-down experiments. mir-144-3p 32-42 nuclear paraspeckle assembly transcript 1 Homo sapiens 23-28 34034455-3 2021 The aim of this study is to investigate the effect of miR-144-3p on the invasion and metastasis of lung adenocarcinoma by targeting recombinant insulin receptor substrate 1 (IRS1). mir-144-3p 54-64 insulin receptor substrate 1 Homo sapiens 144-172 34034455-3 2021 The aim of this study is to investigate the effect of miR-144-3p on the invasion and metastasis of lung adenocarcinoma by targeting recombinant insulin receptor substrate 1 (IRS1). mir-144-3p 54-64 insulin receptor substrate 1 Homo sapiens 174-178 34034455-17 2021 Transwell experiment proved that miR-144-3p could inhibit invasion and metastasis of lung adenocarcinoma cells by targeting IRS1 (P<0.05). mir-144-3p 33-43 insulin receptor substrate 1 Homo sapiens 124-128 34034455-18 2021 CONCLUSIONS: MiR-144-3p inhibits the invasion and migration of A549 cells through targeted regulation of IRS1, thus playing an anticancer role in tumors. mir-144-3p 13-23 insulin receptor substrate 1 Homo sapiens 105-109 33847879-0 2021 LncRNA LOC729178 acts as a sponge of miR-144-3p to mitigate cigarette smoke extract-induced inflammatory injury via regulating PHLPP2 in 16HBE cells. mir-144-3p 37-47 PH domain and leucine rich repeat protein phosphatase 2 Homo sapiens 127-133 33847879-12 2021 PHLPP2 was identified as a direct and functional target of miR-144-3p. mir-144-3p 59-69 PH domain and leucine rich repeat protein phosphatase 2 Homo sapiens 0-6 33995991-9 2021 Overexpression of NEAT1 or ROCK2 promoted immune cell (CD4+T cells) proliferation, Th17 cell differentiation, and cell migration in response to stimulus, whereas knockout of the NEAT1 gene induced the expression of miR-144-3p in CD4+T cells. mir-144-3p 215-225 nuclear paraspeckle assembly transcript 1 Homo sapiens 18-23 33995991-9 2021 Overexpression of NEAT1 or ROCK2 promoted immune cell (CD4+T cells) proliferation, Th17 cell differentiation, and cell migration in response to stimulus, whereas knockout of the NEAT1 gene induced the expression of miR-144-3p in CD4+T cells. mir-144-3p 215-225 Rho associated coiled-coil containing protein kinase 2 Homo sapiens 27-32 33995991-9 2021 Overexpression of NEAT1 or ROCK2 promoted immune cell (CD4+T cells) proliferation, Th17 cell differentiation, and cell migration in response to stimulus, whereas knockout of the NEAT1 gene induced the expression of miR-144-3p in CD4+T cells. mir-144-3p 215-225 nuclear paraspeckle assembly transcript 1 Homo sapiens 178-183 33995991-9 2021 Overexpression of NEAT1 or ROCK2 promoted immune cell (CD4+T cells) proliferation, Th17 cell differentiation, and cell migration in response to stimulus, whereas knockout of the NEAT1 gene induced the expression of miR-144-3p in CD4+T cells. mir-144-3p 215-225 CD4 molecule Homo sapiens 229-232 33995991-10 2021 ROCK2 exogenous expression inhibited the expression of miR-144-3p, inducing activation of the WNT signaling pathway. mir-144-3p 55-65 Rho associated coiled-coil containing protein kinase 2 Homo sapiens 0-5 33465419-11 2021 miR-18a-5p and miR-144-3p also had a significant direct correlation with miR-33a-5p, an important modulator of cholesterol homeostasis. mir-144-3p 15-25 microRNA 33a Homo sapiens 73-80 33845716-0 2021 MiR-144-3p inhibits the proliferation, migration and invasion of lung adenocargen cancer cells by targeting COL11A1. mir-144-3p 0-10 collagen type XI alpha 1 chain Homo sapiens 108-115 33845716-4 2021 Overexpressing miR-144-3p inhibited the proliferation, migration and invasion of LUAD cells, which could be reversed by overexpression of COL11A1. mir-144-3p 15-25 collagen type XI alpha 1 chain Homo sapiens 138-145 33845716-5 2021 Overexpressing miR-144-3p inhibits the proliferation, migration and invasion of LUAD cells by silencing COL11A1. mir-144-3p 15-25 collagen type XI alpha 1 chain Homo sapiens 104-111 33898468-0 2021 Elevated Levels of miR-144-3p Induce Cholinergic Degeneration by Impairing the Maturation of NGF in Alzheimer"s Disease. mir-144-3p 19-29 nerve growth factor Mus musculus 93-96 33898468-5 2021 Here, we demonstrated that levels of miR-144-3p are increased in the hippocampi and the medial prefrontal cortex of an APP/PS1 mouse model of AD. mir-144-3p 37-47 presenilin 1 Mus musculus 123-126 33898468-8 2021 The administration of miR-144-3p fully replicated the cholinergic degeneration and synaptic/memory deficits observed in the APP/PS1 mice. mir-144-3p 22-32 presenilin 1 Mus musculus 128-131 33898468-9 2021 The injection of an antagomir of miR-144-3p into the hippocampi partially rescued cholinergic degeneration and synaptic/memory impairments by restoring the levels of tPA protein and by correcting the ratio of proNGF/NGF. mir-144-3p 33-43 plasminogen activator, tissue Mus musculus 166-169 33898468-9 2021 The injection of an antagomir of miR-144-3p into the hippocampi partially rescued cholinergic degeneration and synaptic/memory impairments by restoring the levels of tPA protein and by correcting the ratio of proNGF/NGF. mir-144-3p 33-43 nerve growth factor Mus musculus 209-219