PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 32244340-3 2020 When active, dNTP triphosphohydrolase activity of SAMHD1 degrades dNTPs into their 2"-deoxynucleoside (dN) and triphosphate subparts, steadily depleting intercellular dNTP pools. 2"-deoxynucleoside 83-101 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens 50-56 33988981-1 2021 SAMHD1 is a fundamental regulator of cellular dNTPs that catalyzes their hydrolysis into 2"-deoxynucleoside and triphosphate, restricting the replication of viruses, including HIV-1, in CD4+ myeloid lineage and resting T-cells. 2"-deoxynucleoside 89-107 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens 0-6 33988981-1 2021 SAMHD1 is a fundamental regulator of cellular dNTPs that catalyzes their hydrolysis into 2"-deoxynucleoside and triphosphate, restricting the replication of viruses, including HIV-1, in CD4+ myeloid lineage and resting T-cells. 2"-deoxynucleoside 89-107 CD4 molecule Homo sapiens 186-189 31296733-1 2019 Vertebrate protein SAMHD1 (sterile-alpha-motif and HD domain containing protein 1) regulates the cellular dNTP (2"-deoxynucleoside-5"-triphosphate) pool by catalysing the hydrolysis of dNTP into 2"-deoxynucleoside and triphosphate products. 2"-deoxynucleoside 112-130 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens 19-25 12081495-20 2002 The covalent 2"-deoxynucleoside inactivators of CD38 are powerful inhibitors by acting as good substrates for formation of the covalent intermediate but are poor leaving groups from the intermediate complex because hydrolytic assistance of the 2"-hydroxyl group is lacking. 2"-deoxynucleoside 13-31 CD38 molecule Homo sapiens 48-52 20854794-2 2011 Six fused-pyrimidine ribonucleosides and one 2"-deoxynucleoside were assessed for their abilities to inhibit [(3)H]uridine transport in the yeast Saccharomyces cerevisiae producing recombinant hCNT1, hCNT2 or hCNT3. 2"-deoxynucleoside 45-63 solute carrier family 28 member 1 Homo sapiens 193-198