PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21115691-7	2010	Mice deficient in IL-1RI signaling showed reduced expression of IL-10 and type I IFN and increased susceptibility to dextran sulphate sodium-induced colitis and failed to mount a protective type I IFN response after TLR9 ligand (CpG) administration.	dextran sulphate sodium	117-140	interleukin 1 receptor type 1	Homo sapiens	18-24
18005362-0	2008	Lactobacillus casei prevents the development of dextran sulphate sodium-induced colitis in Toll-like receptor 4 mutant mice.	dextran sulphate sodium	48-71	toll-like receptor 4	Mus musculus	91-111
18849965-9	2008	Mice lacking Atg16L1 in haematopoietic cells are highly susceptible to dextran sulphate sodium-induced acute colitis, which is alleviated by injection of anti-IL-1beta and IL-18 antibodies, indicating the importance of Atg16L1 in the suppression of intestinal inflammation.	dextran sulphate sodium	71-94	autophagy related 16-like 1 (S. cerevisiae)	Mus musculus	13-20
18849965-9	2008	Mice lacking Atg16L1 in haematopoietic cells are highly susceptible to dextran sulphate sodium-induced acute colitis, which is alleviated by injection of anti-IL-1beta and IL-18 antibodies, indicating the importance of Atg16L1 in the suppression of intestinal inflammation.	dextran sulphate sodium	71-94	interleukin 1 beta	Mus musculus	159-167
18849965-9	2008	Mice lacking Atg16L1 in haematopoietic cells are highly susceptible to dextran sulphate sodium-induced acute colitis, which is alleviated by injection of anti-IL-1beta and IL-18 antibodies, indicating the importance of Atg16L1 in the suppression of intestinal inflammation.	dextran sulphate sodium	71-94	interleukin 18	Mus musculus	172-177
19821118-1	2009	The aim of this study was to investigate the cellular and molecular expression of tartrate resistant acid phosphatase (TRAP) as a marker of activated macrophages in macrophage dependent dextran sulphate sodium (DSS)-induced colitis in rats.	dextran sulphate sodium	186-209	acid phosphatase 5, tartrate resistant	Rattus norvegicus	82-117
19821118-1	2009	The aim of this study was to investigate the cellular and molecular expression of tartrate resistant acid phosphatase (TRAP) as a marker of activated macrophages in macrophage dependent dextran sulphate sodium (DSS)-induced colitis in rats.	dextran sulphate sodium	186-209	acid phosphatase 5, tartrate resistant	Rattus norvegicus	119-123
18662832-3	2008	Less severe histological abnormalities and clinical scores were detected in dextran sulphate sodium (DSS)-induced colitis in IFN-gamma(-/-), compared to Wt, mice.	dextran sulphate sodium	76-99	interferon gamma	Mus musculus	125-134
18495601-0	2008	[Activation of nuclear factor-kappa B and its modulalorg effects on intercellular adhesion molecule-1 expression in mice with dextran sulphate sodium-induced rat colitis].	dextran sulphate sodium	126-149	intercellular adhesion molecule 1	Mus musculus	68-101
18495601-1	2008	OBJECTIVE: To investigate the changes in the activity of nuclear factor-kappaB (NF-kappa B) in mice with dextran sulphate sodium (DSS)-induced rat colitis and its modulalorg effect on intercellular adhesion molecule-1 (ICAM-1) expression.	dextran sulphate sodium	105-128	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	57-78
18495601-1	2008	OBJECTIVE: To investigate the changes in the activity of nuclear factor-kappaB (NF-kappa B) in mice with dextran sulphate sodium (DSS)-induced rat colitis and its modulalorg effect on intercellular adhesion molecule-1 (ICAM-1) expression.	dextran sulphate sodium	105-128	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	80-90
18495601-1	2008	OBJECTIVE: To investigate the changes in the activity of nuclear factor-kappaB (NF-kappa B) in mice with dextran sulphate sodium (DSS)-induced rat colitis and its modulalorg effect on intercellular adhesion molecule-1 (ICAM-1) expression.	dextran sulphate sodium	105-128	intercellular adhesion molecule 1	Rattus norvegicus	184-217
18495601-1	2008	OBJECTIVE: To investigate the changes in the activity of nuclear factor-kappaB (NF-kappa B) in mice with dextran sulphate sodium (DSS)-induced rat colitis and its modulalorg effect on intercellular adhesion molecule-1 (ICAM-1) expression.	dextran sulphate sodium	105-128	intercellular adhesion molecule 1	Rattus norvegicus	219-225
17466962-0	2007	Inhibition of lipopolysaccharide-induced release of interleukin-8 from intestinal epithelial cells by SMA, a novel inhibitor of sphingomyelinase and its therapeutic effect on dextran sulphate sodium-induced colitis in mice.	dextran sulphate sodium	175-198	immunoglobulin mu binding protein 2	Mus musculus	102-105
17768420-4	2007	This is consistent with higher levels of monocyte chemotactic protein-1, interleukin (IL)-6 and granulocyte monocyte colony-stimulating factor (GM-CSF) in the inflamed colon from the TNF-alpha(-/-) mice, compared to the Wt mice, following dextran sulphate sodium (DSS) challenge.	dextran sulphate sodium	239-262	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	144-150
17451462-0	2007	Acid sphingomyelinase inhibition suppresses lipopolysaccharide-mediated release of inflammatory cytokines from macrophages and protects against disease pathology in dextran sulphate sodium-induced colitis in mice.	dextran sulphate sodium	165-188	sphingomyelin phosphodiesterase 1, acid lysosomal	Mus musculus	0-21
16552705-6	2006	First, using a quantitative polymerase chain reaction (PCR), western blotting, and zymography, we determined which MMPs were relevant to experimental colitis induced in mice by dextran sulphate sodium.	dextran sulphate sodium	177-200	matrix metallopeptidase 3	Mus musculus	115-119
16981178-5	2006	IL-15 blockade in chronic dextran sulphate sodium-induced colitis resulted in aggravation of the disease with a significantly 2.1-fold increased epithelial damage score compared to controls.	dextran sulphate sodium	26-49	interleukin 15	Homo sapiens	0-5
15804292-0	2005	Reduced susceptibility to dextran sulphate sodium-induced colitis in the interleukin-2 heterozygous (IL-2) mouse.	dextran sulphate sodium	26-49	interleukin 2	Mus musculus	73-86
16630028-2	2006	Recently it has been demonstrated that p38MAPK (mitogen-activated protein kinase) inhibition using SB203580 is effective in reducing disease in both dextran sulphate sodium (DSS)-induced and 2,4,6-trinitrobenzenesulphonic acid (TNBS)-induced murine colitides, underscoring the importance of this pathway in gastrointestinal inflammation.	dextran sulphate sodium	149-172	mitogen-activated protein kinase 14	Mus musculus	39-46
16162679-0	2006	Role of interleukin 15 in colitis induced by dextran sulphate sodium in mice.	dextran sulphate sodium	45-68	interleukin 15	Mus musculus	8-22
16162679-3	2006	Here we investigated the involvement of IL-15 in the pathogenesis of acute and chronic dextran sulphate sodium (DSS) induced colitis.	dextran sulphate sodium	87-110	interleukin 15	Mus musculus	40-45
16045730-0	2005	Macrophage migration inhibitory factor contributes to the development of acute dextran sulphate sodium-induced colitis in Toll-like receptor 4 knockout mice.	dextran sulphate sodium	79-102	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mus musculus	0-38
16045730-0	2005	Macrophage migration inhibitory factor contributes to the development of acute dextran sulphate sodium-induced colitis in Toll-like receptor 4 knockout mice.	dextran sulphate sodium	79-102	toll-like receptor 4	Mus musculus	122-142
15807847-2	2005	To further investigate this matter, we examined the pathological features of MIF transgenic mice with dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	102-125	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mus musculus	77-80
15804292-0	2005	Reduced susceptibility to dextran sulphate sodium-induced colitis in the interleukin-2 heterozygous (IL-2) mouse.	dextran sulphate sodium	26-49	interleukin 2	Mus musculus	101-105
15804292-4	2005	When exposed to dextran sulphate sodium (DSS) IL-2+/- mice showed a markedly reduced susceptibility to DSS-induced colitis.	dextran sulphate sodium	16-39	interleukin 2	Mus musculus	46-50
15883736-0	2005	The COX-2 inhibitor, rofecoxib, ameliorates dextran sulphate sodium induced colitis in mice.	dextran sulphate sodium	44-67	cytochrome c oxidase II, mitochondrial	Mus musculus	4-9
15601431-0	2004	Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice.	dextran sulphate sodium	63-86	transient receptor potential cation channel, subfamily V, member 1	Mus musculus	0-20
15601431-2	2004	Vanilloid receptor type 1 (TRPV1) has been visualized on nerve terminals of intrinsic and extrinsic afferent neurones innervating the gastrointestinal tract and local administration of a TRPV1 antagonist, capsazepine, reduces the severity of dextran sulphate sodium (DSS)-induced colitis in rats (Gut 2003; 52: 713-9(1)).	dextran sulphate sodium	242-265	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	27-32
15298625-7	2004	Recent studies suggest that the induction of HO-1 expression plays a critical protective role in intestinal damage models induced by trinitrobenzene sulphonic acid or dextran sulphate sodium, indicating that activation of HO-1 may act as an endogenous defensive mechanism to reduce inflammation and tissue injury in the intestinal tract.	dextran sulphate sodium	167-190	heme oxygenase 1	Homo sapiens	45-49
15601431-2	2004	Vanilloid receptor type 1 (TRPV1) has been visualized on nerve terminals of intrinsic and extrinsic afferent neurones innervating the gastrointestinal tract and local administration of a TRPV1 antagonist, capsazepine, reduces the severity of dextran sulphate sodium (DSS)-induced colitis in rats (Gut 2003; 52: 713-9(1)).	dextran sulphate sodium	242-265	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	187-192
15298625-7	2004	Recent studies suggest that the induction of HO-1 expression plays a critical protective role in intestinal damage models induced by trinitrobenzene sulphonic acid or dextran sulphate sodium, indicating that activation of HO-1 may act as an endogenous defensive mechanism to reduce inflammation and tissue injury in the intestinal tract.	dextran sulphate sodium	167-190	heme oxygenase 1	Homo sapiens	222-226
12692058-0	2003	Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats.	dextran sulphate sodium	65-88	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	0-20
15082590-0	2004	Development of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulphate sodium.	dextran sulphate sodium	92-115	transformation related protein 53, pseudogene	Mus musculus	36-39
15082590-3	2004	AIMS: To establish a new colitis associated neoplasia model in p53 deficient mice by treatment with dextran sulphate sodium (DSS).	dextran sulphate sodium	100-123	transformation related protein 53, pseudogene	Mus musculus	63-66
15030510-2	2004	To investigate the mechanisms by which LTbetaR activation contributes to the pathology of chronic inflammation we used a soluble LTbetaR-Ig fusion protein as a competitive inhibitor of LTbetaR activation in the mouse model of chronic colitis induced by oral administration of dextran sulphate sodium.	dextran sulphate sodium	276-299	lymphotoxin B receptor	Mus musculus	129-136
15030510-2	2004	To investigate the mechanisms by which LTbetaR activation contributes to the pathology of chronic inflammation we used a soluble LTbetaR-Ig fusion protein as a competitive inhibitor of LTbetaR activation in the mouse model of chronic colitis induced by oral administration of dextran sulphate sodium.	dextran sulphate sodium	276-299	lymphotoxin B receptor	Mus musculus	129-136
15030527-4	2004	The expression of cathepsin D in intestinal mucosa was analysed by immunohistochemistry in biopsies from IBD and control patients and in a mouse model of dextran sulphate sodium (DSS)-induced acute and chronic colitis.	dextran sulphate sodium	154-177	cathepsin D	Homo sapiens	18-29
12940437-2	2003	The present study was conducted to determine the distinct roles of IL-12 and IL-18 in the development of dextran sulphate sodium (DSS) colitis in mice.	dextran sulphate sodium	105-128	interleukin 18	Mus musculus	77-82
12010883-0	2002	Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage.	dextran sulphate sodium	73-96	interleukin 18	Mus musculus	0-14
12010883-0	2002	Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage.	dextran sulphate sodium	73-96	interleukin 18	Mus musculus	123-137
12010883-6	2002	METHODS: Mice with dextran sulphate sodium (DSS) induced colitis were treated with recombinant IL-18 binding protein (IL-18bp.Fc), a soluble protein that blocks IL-18 bioactivity.	dextran sulphate sodium	19-42	interleukin 18	Homo sapiens	95-100
9517530-0	1998	Insulin-like growth factor-I partially attenuates colonic damage in rats with experimental colitis induced by oral dextran sulphate sodium.	dextran sulphate sodium	115-138	insulin-like growth factor 1	Rattus norvegicus	0-28
10759763-0	2000	Therapeutic effect of intracolonically administered nuclear factor kappa B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	116-139	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	76-79
11196714-4	2000	IL-5 deficient mice were studied using the dextran sulphate sodium (DSS)-induced colitis model and the results compared to a congenic IL-5+/+ strain.	dextran sulphate sodium	43-66	interleukin 5	Mus musculus	0-4
9844047-0	1998	Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines.	dextran sulphate sodium	40-63	negative elongation factor complex member C/D, Th1l	Mus musculus	90-93
9844047-0	1998	Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines.	dextran sulphate sodium	40-63	heart and neural crest derivatives expressed 2	Mus musculus	98-101
11607786-0	2001	Dextran sulphate sodium-induced colitis is ameliorated in interleukin 4 deficient mice.	dextran sulphate sodium	0-23	interleukin 4	Mus musculus	58-71
11607786-9	2001	Dextran sulphate sodium-induced colitis is ameliorated in IL-4 deficient mice.	dextran sulphate sodium	0-23	interleukin 4	Mus musculus	58-62
10337013-0	1999	Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice.	dextran sulphate sodium	122-145	interferon gamma	Mus musculus	0-27
10337013-0	1999	Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice.	dextran sulphate sodium	122-145	tumor necrosis factor	Mus musculus	34-56
10337013-0	1999	Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice.	dextran sulphate sodium	122-145	tumor necrosis factor	Mus musculus	58-61
9504889-0	1997	Selective depletion of neutrophils by a monoclonal antibody, RP-3, suppresses dextran sulphate sodium-induced colitis in rats.	dextran sulphate sodium	78-101	microtubule-associated protein, RP/EB family, member 3	Rattus norvegicus	61-65
33482271-3	2021	Carbon monoxide (CO) is an important gaseous molecule with versatile functions including anti-oxidation and anti-inflammation, and we previous reported the therapeutic potential of a nano-designed CO donor SMA/CORM2 in a dextran sulphate sodium (DSS) induced mouse colitis model.	dextran sulphate sodium	221-244	immunoglobulin mu binding protein 2	Mus musculus	206-209
9030875-0	1997	Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice.	dextran sulphate sodium	95-118	tumor necrosis factor	Mus musculus	18-40
9030875-0	1997	Neutralization of tumour necrosis factor (TNF) but not of IL-1 reduces inflammation in chronic dextran sulphate sodium-induced colitis in mice.	dextran sulphate sodium	95-118	tumor necrosis factor	Mus musculus	42-45
34577566-0	2021	Exacerbation of Liver Tumor Metastasis in twist1a+/xmrk+ Double Transgenic Zebrafish following Lipopolysaccharide or Dextran Sulphate Sodium Exposure.	dextran sulphate sodium	117-140	twist family bHLH transcription factor 1a	Danio rerio	42-49
35331316-5	2022	RESULTS: Chronic colitis models of CagA+ H. pylori-colonized mice treated with 2% Dextran sulphate sodium (DSS) were established to assess the disease activity and pertinent expression of tight junction proteins closely related to mucosal integrity.	dextran sulphate sodium	82-105	S100 calcium binding protein A8	Homo sapiens	35-39
33569850-5	2021	We showed for the first time that miR-21a-5p expression is increased in the peritoneal exosomes of mice with dextran sulphate sodium induced enteritis and that miR-21a-5p expression correlates negatively with E-cadherin expression in enterocytes.	dextran sulphate sodium	109-132	microRNA 21a	Mus musculus	34-41
33569850-5	2021	We showed for the first time that miR-21a-5p expression is increased in the peritoneal exosomes of mice with dextran sulphate sodium induced enteritis and that miR-21a-5p expression correlates negatively with E-cadherin expression in enterocytes.	dextran sulphate sodium	109-132	cadherin 1	Mus musculus	209-219
33491282-7	2021	Conditional ITGB6 transgene expression exacerbated experimental colitis in mouse models of acute and chronic dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	109-132	integrin beta 6	Mus musculus	12-17
32350653-1	2021	PURPOSE: The study aimed to investigate the discrepancy and potential mechanisms of different CLA-producing B. breve on dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	120-143	clasper	Mus musculus	94-97
33075564-3	2021	METHOD: Fibrinogen level was measured in dextran sulphate sodium (DSS)-induced colitis and patients with ulcerative colitis.	dextran sulphate sodium	41-64	fibrinogen beta chain	Homo sapiens	8-18
32805281-5	2020	CCAT2 transgene and control mice were given azoxymethane and dextran sulphate sodium (DSS) to induce colon tumors.	dextran sulphate sodium	61-84	colon cancer associated transcript 2	Homo sapiens	0-5
31772324-3	2020	Using infectious (Citrobacter rodentium) and chemical (dextran sulphate sodium; DSS) murine colitis models, as well as human IBD samples, we find that faecal neutrophil elastase (NE) activity reflects disease severity.	dextran sulphate sodium	55-78	elastase, neutrophil expressed	Homo sapiens	158-177
32958515-4	2020	The highest-ranked drug was the macrolide antibiotic Clarithromycin, which has previously been reported to have anti-inflammatory effects in aseptic conditions.Clarithromycin"s effects were validated in several experiments: it influenced NF-kappaB mediated transcription in murine peritoneal macrophages and intestinal enteroids; it suppressed NF-kappaB protein shuttling in murine reporter enteroids; it suppressed NF-kappaB (p65) DNA binding in the small intestine of mice exposed to LPS, and it reduced the severity of dextran sulphate sodium-induced colitis in C57BL/6 mice.	dextran sulphate sodium	522-545	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	238-247
31454000-1	2019	In this study, we aimed at investigating the antiinflammatory activity of the freeze-dried fruit powder of Actinidia arguta (FAA) on dextran sulphate sodium (DSS)-induced ulcerative colitis (UC) in mice and the effect of its extract on lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages.	dextran sulphate sodium	133-156	fumarylacetoacetate hydrolase	Mus musculus	125-128
30375302-3	2019	In this study, microRNA-array differential analysis revealed strongly enhanced expression of miR-24-1-5p in the colon tissue of azoxymethane/dextran sulphate sodium-induced mice that were fed with black raspberry anthocyanins for 9 weeks.	dextran sulphate sodium	141-164	microRNA 24-1	Mus musculus	93-101
30790702-6	2019	Socially defeated mice with KA treatment displayed enhanced vulnerability to subsequent dextran sulphate sodium (DSS)-induced colonic injury and inflammatory disturbance, and this effect was reversed by autophagic inhibition that blocked the NLRP3-suppressive effect of KA.	dextran sulphate sodium	88-111	NLR family, pyrin domain containing 3	Mus musculus	242-247
31060167-1	2019	Objective: To investigate the impact of TNF-related apoptosis-inducing ligand (TRAIL) gene knock-out (TRAIL(-/-)) on Th17 cells in the mice colitis induced by dextran sulphate sodium (DSS).	dextran sulphate sodium	159-182	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	40-77
31060167-1	2019	Objective: To investigate the impact of TNF-related apoptosis-inducing ligand (TRAIL) gene knock-out (TRAIL(-/-)) on Th17 cells in the mice colitis induced by dextran sulphate sodium (DSS).	dextran sulphate sodium	159-182	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	79-84
31060167-1	2019	Objective: To investigate the impact of TNF-related apoptosis-inducing ligand (TRAIL) gene knock-out (TRAIL(-/-)) on Th17 cells in the mice colitis induced by dextran sulphate sodium (DSS).	dextran sulphate sodium	159-182	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	102-107
31061672-0	2019	Gut Microbiota-Mediated NLRP12 Expression Drives the Attenuation of Dextran Sulphate Sodium-Induced Ulcerative Colitis by Qingchang Wenzhong Decoction.	dextran sulphate sodium	68-91	NLR family, pyrin domain containing 12	Rattus norvegicus	24-30
30097122-0	2018	Eupatilin ameliorates dextran sulphate sodium-induced colitis in mice partly through promoting AMPK activation.	dextran sulphate sodium	22-45	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	95-99
31527366-2	2019	The present study aimed to elucidate the expression of TRPV4 in the gastrointestinal tract and the pathogenic roles of TRPV4 in dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	128-151	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	119-124
29969845-0	2018	Peyer"s patches-derived CD11b+ B cells recruit regulatory T cells through CXCL9 in dextran sulphate sodium-induced colitis.	dextran sulphate sodium	83-106	integrin subunit alpha M	Homo sapiens	24-29
29969845-0	2018	Peyer"s patches-derived CD11b+ B cells recruit regulatory T cells through CXCL9 in dextran sulphate sodium-induced colitis.	dextran sulphate sodium	83-106	C-X-C motif chemokine ligand 9	Homo sapiens	74-79
30382081-7	2018	In vivo, inhibition of Cbl with an analgesic drug, hydrocotarnine, increases inflammasome-mediated IL-18 secretion in the colon, and protects mice from dextran sulphate sodium-induced colitis.	dextran sulphate sodium	152-175	Casitas B-lineage lymphoma	Mus musculus	23-26
29992488-4	2018	AhR activation by 6-formylindolo (3,2-b) carbazole (FICZ) represses the abnormal expression of the Par complex in a mouse model of dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	131-154	aryl-hydrocarbon receptor	Mus musculus	0-3
29945292-0	2018	Activating the pregnane X receptor by imperatorin attenuates dextran sulphate sodium-induced colitis in mice.	dextran sulphate sodium	61-84	nuclear receptor subfamily 1, group I, member 2	Mus musculus	15-34
29710547-0	2018	NF-kappaB and Nrf2 pathways contribute to the protective effect of Licochalcone A on dextran sulphate sodium-induced ulcerative colitis in mice.	dextran sulphate sodium	85-108	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	0-9
29710547-0	2018	NF-kappaB and Nrf2 pathways contribute to the protective effect of Licochalcone A on dextran sulphate sodium-induced ulcerative colitis in mice.	dextran sulphate sodium	85-108	nuclear factor, erythroid derived 2, like 2	Mus musculus	14-18
28287113-4	2018	Intestinal epithelial cell (IEC)-specific deletion of TC-PTP was achieved in a mouse model at steady state and in the context of dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	129-152	protein tyrosine phosphatase, non-receptor type 2	Mus musculus	54-60
29680209-4	2018	Our data show that AhR activation by FICZ ameliorated colonic inflammation, decreased IL-6 and claudin-2 expression, and maintained intestinal barrier function in a mouse model of dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	180-203	aryl-hydrocarbon receptor	Mus musculus	19-22
29572384-3	2018	Colitis was induced in CT-1 knockout and wild-type (WT) mice by administration of dextran sulphate sodium (DSS) in the drinking water during 7 days.	dextran sulphate sodium	82-105	cardiotrophin 1	Mus musculus	23-27
29475099-0	2018	Andrographolide derivative CX-10 ameliorates dextran sulphate sodium-induced ulcerative colitis in mice: Involvement of NF-kappaB and MAPK signalling pathways.	dextran sulphate sodium	45-68	mitogen-activated protein kinase 1	Mus musculus	134-138
29366768-3	2018	AIM OF THE STUDY: This study aimed to verify the interactions by examining the impact of GP on oral pharmacokinetics of ginsenoside Rb1 (Rb1), the dominant protopanoxadiol (PPD)-type ginsenoside in Ginseng, on a dextran sulphate sodium (DSS) induced experimental colitis model which was characterized by gut dysbiosis, and to delineate the underlying mechanisms in vitro.	dextran sulphate sodium	212-235	RB transcriptional corepressor 1	Homo sapiens	137-140
29053877-0	2018	Transient receptor potential vanilloid 4 channel regulates vascular endothelial permeability during colonic inflammation in dextran sulphate sodium-induced murine colitis.	dextran sulphate sodium	124-147	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	0-40
28987000-4	2018	To monitor further the possible effect of miR-126 deficiency on the function of CD4+ T cells in vivo, we used dextran sulphate sodium (DSS)-induced murine model of acute autoimmune colitis and found that miR-126 deficiency could elevate the pathology of colitis.	dextran sulphate sodium	110-133	microRNA 126a	Mus musculus	204-211
29115460-3	2018	The aim of the present study was to investigate the function of CRF receptor 1 (CRF-R1) in the development of mucosal inflammation induced by dextran sulphate sodium (DSS) and the underlying mechanism.	dextran sulphate sodium	142-165	corticotropin releasing hormone receptor 1	Mus musculus	64-78
29053877-2	2018	The present study aimed to elucidate the function and expression of TRPV4 channels in colonic vascular endothelial cells during dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	128-151	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	68-73
29115460-3	2018	The aim of the present study was to investigate the function of CRF receptor 1 (CRF-R1) in the development of mucosal inflammation induced by dextran sulphate sodium (DSS) and the underlying mechanism.	dextran sulphate sodium	142-165	corticotropin releasing hormone receptor 1	Mus musculus	80-86
28572005-1	2017	We previously reported that reelin, an extracellular matrix protein first known for its key role in neuronal migration, reduces the susceptibility to dextran sulphate sodium (DSS)-colitis.	dextran sulphate sodium	150-173	reelin	Mus musculus	28-34
29057966-1	2017	Mice deficient in the megakaryoblastic leukaemia 1 (Mkl1) gene experience less severe dextran sulphate sodium (DSS)-induced colitis, implying that Mkl1 plays a pathological role in inflammatory bowel disease (IBD).	dextran sulphate sodium	86-109	myocardin related transcription factor A	Mus musculus	22-50
29057966-1	2017	Mice deficient in the megakaryoblastic leukaemia 1 (Mkl1) gene experience less severe dextran sulphate sodium (DSS)-induced colitis, implying that Mkl1 plays a pathological role in inflammatory bowel disease (IBD).	dextran sulphate sodium	86-109	myocardin related transcription factor A	Mus musculus	52-56
29057966-1	2017	Mice deficient in the megakaryoblastic leukaemia 1 (Mkl1) gene experience less severe dextran sulphate sodium (DSS)-induced colitis, implying that Mkl1 plays a pathological role in inflammatory bowel disease (IBD).	dextran sulphate sodium	86-109	myocardin related transcription factor A	Mus musculus	147-151
30298837-0	2018	[TRPV4 regulates vascular endothelial permeability during colonic inflammation in dextran sulphate sodium-induced murine colitis].	dextran sulphate sodium	82-105	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	1-6
30298837-2	2018	The present study aimed to elucidate the function and expression of TRPV4 in colonic vascular endothelial cells during dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	119-142	transient receptor potential cation channel, subfamily V, member 4	Mus musculus	68-73
28535907-3	2017	In this study, we determined the role of A-kinase anchor protein 13 (AKAP13) in mice with dextran sulphate sodium (DSS)-induced colitis upon mucosal injury and restitution, and investigated whether inhibition of Rho-associated coiled-coil containing protein kinase (ROCK), downstream effector of AKAP13, affects these mucosal responses.	dextran sulphate sodium	90-113	A kinase (PRKA) anchor protein 13	Mus musculus	69-75
28320072-4	2017	EXPERIMENTAL APPROACH: CAR expression was assessed in intestinal mucosal biopsies obtained from CD and UC patients, and in C57/Bl6 mice exposed to dextran sulphate sodium (DSS; 3.5% w/v in drinking water) to evoke intestinal inflammation and tissue damage.	dextran sulphate sodium	147-170	nuclear receptor subfamily 1 group I member 3	Homo sapiens	23-26
28380665-3	2017	In the dextran sulphate sodium-induced acute colitis mouse model, FCN-A knockout mice showed much milder disease symptoms with less histological damage, lower expression levels of pro-inflammatory cytokines [interleukin-6 (IL-6), IL-1beta and tumour necrosis factor-alpha (TNF-alpha)], chemokines (CXCL1/2/10 and CCL4) and higher levels of the anti-inflammatory cytokine IL-10 compared with wild-type mice.	dextran sulphate sodium	7-30	ficolin A	Mus musculus	66-71
28455963-5	2017	In this study, TrkC was frequently overexpressed in CRC cells, patients" tumor samples and an azoxymethane/dextran sulphate sodium-induced mouse model of colitis-associated CRCs.	dextran sulphate sodium	107-130	neurotrophic receptor tyrosine kinase 3	Homo sapiens	15-19
28648739-4	2017	GPR35 function was examined in a wound healing model, using young adult mouse colon epithelium (YAMC) cells, and in a dextran sulphate sodium (DSS)-induced mouse model of colitis.	dextran sulphate sodium	118-141	G protein-coupled receptor 35	Mus musculus	0-5
28339048-2	2017	Anterior gradient protein 2 homologue (AGR2) assists in maintaining intestinal homeostasis in dextran sulphate sodium-induced mouse ileocolitis; however, it is unclear whether it modulates intestinal barrier function.	dextran sulphate sodium	94-117	anterior gradient 2	Mus musculus	39-43
28383063-0	2017	Rosmarinic acid suppresses colonic inflammation in dextran sulphate sodium (DSS)-induced mice via dual inhibition of NF-kappaB and STAT3 activation.	dextran sulphate sodium	51-74	signal transducer and activator of transcription 3	Mus musculus	131-136
28008786-7	2017	When dextran sulphate sodium-induced colitic mice were treated with GI7, their symptoms of colitis, as assessed by body weight, colon length, myeloperoxidase activity, intestinal bleeding, and histological damage, were reduced compared to untreated mice.	dextran sulphate sodium	5-28	myeloperoxidase	Mus musculus	142-157
28079248-0	2017	Inhibition of matrix metalloproteinase-9 by a barbiturate-nitrate hybrid ameliorates dextran sulphate sodium-induced colitis: effect on inflammation-related genes.	dextran sulphate sodium	85-108	matrix metallopeptidase 9	Rattus norvegicus	14-40
27921309-4	2017	We report here that the expression of HIF-1alpha and IL-33 was increased significantly in the inflamed mucosa of IBD patients as well as mice with colitis induced by dextran sulphate sodium (DSS).	dextran sulphate sodium	166-189	hypoxia inducible factor 1 subunit alpha	Homo sapiens	38-48
27921309-4	2017	We report here that the expression of HIF-1alpha and IL-33 was increased significantly in the inflamed mucosa of IBD patients as well as mice with colitis induced by dextran sulphate sodium (DSS).	dextran sulphate sodium	166-189	interleukin 33	Homo sapiens	53-58
26990520-0	2016	5-HT3 receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitis.	dextran sulphate sodium	101-124	tachykinin 1	Mus musculus	63-74
27981571-4	2017	Here, we demonstrated that Phd1 deletion in endothelial and haematopoietic cells (Phd1f/f Tie2:cre) protected mice from dextran sulphate sodium (DSS)-induced colitis, with reduced epithelial erosions, immune cell infiltration, and colonic microvascular dysfunction, whereas the response of Phd2f/+ Tie2:cre and Phd3f/f Tie2:cre mice to DSS was similar to that of their littermate controls.	dextran sulphate sodium	120-143	egl-9 family hypoxia-inducible factor 2	Mus musculus	27-31
27981571-4	2017	Here, we demonstrated that Phd1 deletion in endothelial and haematopoietic cells (Phd1f/f Tie2:cre) protected mice from dextran sulphate sodium (DSS)-induced colitis, with reduced epithelial erosions, immune cell infiltration, and colonic microvascular dysfunction, whereas the response of Phd2f/+ Tie2:cre and Phd3f/f Tie2:cre mice to DSS was similar to that of their littermate controls.	dextran sulphate sodium	120-143	TEK receptor tyrosine kinase	Mus musculus	90-94
27707514-4	2017	In this study we investigated mice proficient or deficient for the expression of the CX3CR1 receptor in a model of dextran sulphate sodium (DSS) induced acute colitis.	dextran sulphate sodium	115-138	chemokine (C-X3-C motif) receptor 1	Mus musculus	85-91
29234405-2	2017	Our previous study found that Qingchang Wenzhong Decoction (QCWZD) can significantly improve the clinical symptoms of UC and ameliorate dextran sulphate sodium- (DSS-) induced ulcerative colitis in rats by downregulating the IP10/CXCR3 axis-mediated inflammatory response.	dextran sulphate sodium	136-159	C-X-C motif chemokine ligand 10	Rattus norvegicus	225-229
27626448-5	2016	Dextran sulphate sodium (DSS)-colitis was used as a model for intestinal inflammatory stress, which elicited a strong upregulation and widened crypt distribution of K7 and K20.	dextran sulphate sodium	0-23	keratin 20	Homo sapiens	172-175
27915032-3	2017	Here we determined in mice colon, by real time-PCR and immunological assays, the expression of the reelin signalling system; its response to dextran sulphate sodium (DSS) and the response of wild-type and reeler mice to DSS-treatment.	dextran sulphate sodium	141-164	reelin	Mus musculus	99-105
27510419-7	2017	Four-day treatment with dextran sulphate sodium (DSS) triggered colon inflammation, as evidenced by an increase in local IL6 and mKC mRNA levels, but did not affect the gross architecture of colonic epithelium.	dextran sulphate sodium	24-47	interleukin 6	Homo sapiens	121-124
26431492-5	2015	Here we demonstrate that CHI3L1 (aka Brp39) knockout (KO) mice treated with azoxymethane (AOM)/dextran sulphate sodium (DSS) developed severe colitis but lesser incidence of CAC as compared to that in wild-type (WT) mice.	dextran sulphate sodium	95-118	chitinase-like 1	Mus musculus	25-31
26950306-4	2016	In the present study, we found that Wip1 knockout (KO) mice were more susceptible to colitis induced by dextran sulphate sodium (DSS) than wild-type mice as substantiated by the lower mouse survival ratio, rapid bodyweight loss, increased disease activity index, shorter colon length, and more severe pathology of colons in Wip1KO mice.	dextran sulphate sodium	104-127	protein phosphatase 1D magnesium-dependent, delta isoform	Mus musculus	36-40
26701127-5	2016	In the colon of mice with dextran sulphate sodium-induced colitis and in patients with CD, only IL-36alpha, gamma and IL-38 were induced at relatively low levels and correlated with IL-1beta and IL-17A.	dextran sulphate sodium	26-49	interleukin 36 alpha	Homo sapiens	96-106
26701127-5	2016	In the colon of mice with dextran sulphate sodium-induced colitis and in patients with CD, only IL-36alpha, gamma and IL-38 were induced at relatively low levels and correlated with IL-1beta and IL-17A.	dextran sulphate sodium	26-49	interleukin 1 family member 10	Homo sapiens	118-123
26701127-5	2016	In the colon of mice with dextran sulphate sodium-induced colitis and in patients with CD, only IL-36alpha, gamma and IL-38 were induced at relatively low levels and correlated with IL-1beta and IL-17A.	dextran sulphate sodium	26-49	interleukin 1 beta	Homo sapiens	182-190
26701127-5	2016	In the colon of mice with dextran sulphate sodium-induced colitis and in patients with CD, only IL-36alpha, gamma and IL-38 were induced at relatively low levels and correlated with IL-1beta and IL-17A.	dextran sulphate sodium	26-49	interleukin 17A	Homo sapiens	195-201
27115526-4	2016	The aim of this study was to investigate the role of PTPN2 in colon epithelial cells by performing dextran sulphate sodium (DSS)-induced colitis in PTPN2xVilCre mice.	dextran sulphate sodium	99-122	protein tyrosine phosphatase, non-receptor type 2	Mus musculus	53-58
27413386-0	2016	Qingchang Wenzhong Decoction Ameliorates Dextran Sulphate Sodium-Induced Ulcerative Colitis in Rats by Downregulating the IP10/CXCR3 Axis-Mediated Inflammatory Response.	dextran sulphate sodium	41-64	C-X-C motif chemokine ligand 10	Rattus norvegicus	122-126
27413386-0	2016	Qingchang Wenzhong Decoction Ameliorates Dextran Sulphate Sodium-Induced Ulcerative Colitis in Rats by Downregulating the IP10/CXCR3 Axis-Mediated Inflammatory Response.	dextran sulphate sodium	41-64	C-X-C motif chemokine receptor 3	Rattus norvegicus	127-132
27610005-5	2016	Colitis was induced in wild-type (WT) and Nlrp3-/- mice by treatment with dextran sulphate sodium (DSS).	dextran sulphate sodium	74-97	NLR family, pyrin domain containing 3	Mus musculus	42-47
27057168-0	2016	Pharmacological Inhibition of Gal-3 in Mesenchymal Stem Cells Enhances Their Capacity to Promote Alternative Activation of Macrophages in Dextran Sulphate Sodium-Induced Colitis.	dextran sulphate sodium	138-161	lectin, galactose binding, soluble 3	Mus musculus	30-35
26431492-5	2015	Here we demonstrate that CHI3L1 (aka Brp39) knockout (KO) mice treated with azoxymethane (AOM)/dextran sulphate sodium (DSS) developed severe colitis but lesser incidence of CAC as compared to that in wild-type (WT) mice.	dextran sulphate sodium	95-118	chitinase-like 1	Mus musculus	37-42
24795796-0	2014	A Probiotic Preparation Duolac-Gold Ameliorates Dextran Sulphate Sodium-induced Mouse Colitis by Downregulating the Expression of IL-6.	dextran sulphate sodium	48-71	interleukin 6	Mus musculus	130-134
26031185-2	2015	We hypothesized that prior voluntary exercise would attenuate colonic inflammation and ameliorate clinical symptoms in dextran sulphate sodium (DSS)-induced ulcerative colitis by increasing glucocorticoid production and up-regulating PPAR-gamma activity in the colon.	dextran sulphate sodium	119-142	peroxisome proliferator activated receptor gamma	Mus musculus	234-244
25183423-4	2014	Dextran sulphate sodium (DSS)-induced colitis leads to accumulation of bile acids in inflamed colon tissues via activation of the intestinal peroxisome PPARalpha-UGTs pathway.	dextran sulphate sodium	0-23	peroxisome proliferator activated receptor alpha	Homo sapiens	152-161
25968904-2	2015	Here we report that the non-muscle-myosin-II (NMII) heavy chain Myh9 accumulates at epithelial injury sites in mice distal colon treated with dextran sulphate sodium (DSS).	dextran sulphate sodium	142-165	myosin, heavy polypeptide 9, non-muscle	Mus musculus	64-68
25825652-4	2015	METHODS: The temporal expression of GHSR/ghrelin was determined in dextran sulphate sodium (DSS) induced colitis in Wt mice.	dextran sulphate sodium	67-90	growth hormone secretagogue receptor	Mus musculus	36-40
25825652-4	2015	METHODS: The temporal expression of GHSR/ghrelin was determined in dextran sulphate sodium (DSS) induced colitis in Wt mice.	dextran sulphate sodium	67-90	ghrelin	Mus musculus	41-48
25293413-2	2015	Using mice deficient in C1q/mannose-binding lectin (MBL) or C3, we demonstrated an important role for these opsonins and/or the classical pathway C3 convertase in providing protection against mucosal injury and infection in a model of chronic dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	243-266	mannose-binding lectin (protein C) 2	Mus musculus	24-50
25293413-2	2015	Using mice deficient in C1q/mannose-binding lectin (MBL) or C3, we demonstrated an important role for these opsonins and/or the classical pathway C3 convertase in providing protection against mucosal injury and infection in a model of chronic dextran sulphate sodium (DSS)-induced colitis.	dextran sulphate sodium	243-266	mannose-binding lectin (protein C) 2	Mus musculus	52-55
24486481-11	2014	Treating mice with a rodent specific PXR agonist, pregnenolone 16alpha-carbonitrile (PCN), attenuated the intestinal barrier dysfunction observed in the dextran sulphate sodium (DSS) model of experimental colitis, an effect that occurred independent of the known anti-inflammatory effects of PCN.	dextran sulphate sodium	153-176	nuclear receptor subfamily 1, group I, member 2	Mus musculus	37-40
24966911-0	2014	Role of far upstream element binding protein 1 in colonic epithelial disruption during dextran sulphate sodium-induced murine colitis.	dextran sulphate sodium	87-110	far upstream element (FUSE) binding protein 1	Mus musculus	8-46
24374874-2	2014	We hypothesized that NIRF probes activatable by cathepsins or metalloproteinases will detect and quantify dextran sulphate sodium (DSS)-induced acute colonic inflammation in wild type mice or chronic colitis in interleukin-10 (IL-10)-null mice ex vivo or in vivo.	dextran sulphate sodium	106-129	interleukin 10	Mus musculus	211-225
24117005-3	2014	In this study, we found that TRAIL-R-deficient mice exhibited a higher incidence of colitis and colitis-associated cancer than that of wild-type (WT) mice, and TRAIL-R expression was down-regulated in WT mice that were fed dextran sulphate sodium.	dextran sulphate sodium	223-246	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	29-34
24117005-3	2014	In this study, we found that TRAIL-R-deficient mice exhibited a higher incidence of colitis and colitis-associated cancer than that of wild-type (WT) mice, and TRAIL-R expression was down-regulated in WT mice that were fed dextran sulphate sodium.	dextran sulphate sodium	223-246	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	160-165
24374874-2	2014	We hypothesized that NIRF probes activatable by cathepsins or metalloproteinases will detect and quantify dextran sulphate sodium (DSS)-induced acute colonic inflammation in wild type mice or chronic colitis in interleukin-10 (IL-10)-null mice ex vivo or in vivo.	dextran sulphate sodium	106-129	interleukin 10	Mus musculus	227-232
24146755-2	2013	Here we report that RASSF1A is a novel regulator of intestinal inflammation as Rassf1a(+/-) , Rassf1a(-/-) and an intestinal epithelial cell specific knockout mouse (Rassf1a (IEC-KO) ) rapidly became sick following dextran sulphate sodium (DSS) administration, a chemical inducer of colitis.	dextran sulphate sodium	215-238	Ras association (RalGDS/AF-6) domain family member 1	Mus musculus	20-27
23582173-3	2013	Significantly, we demonstrate here that IL33 and ST2 are the primary early genes induced in the inflamed colon of BALB/c mice following dextran sulphate sodium (DSS)-induced experimental ulcerative colitis.	dextran sulphate sodium	136-159	interleukin 33	Mus musculus	40-44
23942946-1	2013	The aim of this study was to determine the therapeutic efficacy of lactoferrin (Lf) on dextran sulphate sodium (DSS)-induced experimental colitis in BALB/c mice.	dextran sulphate sodium	87-110	lactotransferrin	Mus musculus	67-78
23668821-3	2013	Chronic colitis was induced in Bim-deficient mice (Bim(-/-) ) with dextran sulphate sodium (DSS).	dextran sulphate sodium	67-90	BCL2-like 11 (apoptosis facilitator)	Mus musculus	31-34
23668821-3	2013	Chronic colitis was induced in Bim-deficient mice (Bim(-/-) ) with dextran sulphate sodium (DSS).	dextran sulphate sodium	67-90	BCL2-like 11 (apoptosis facilitator)	Mus musculus	51-54
23668821-6	2013	Upon chronic dextran sulphate sodium (DSS)-induced colitis, Bim(-/-) animals exhibited an increased infiltrate of lymphocytes into the mucosa compared to wild-type mice.	dextran sulphate sodium	13-36	BCL2-like 11 (apoptosis facilitator)	Mus musculus	60-63
23942946-1	2013	The aim of this study was to determine the therapeutic efficacy of lactoferrin (Lf) on dextran sulphate sodium (DSS)-induced experimental colitis in BALB/c mice.	dextran sulphate sodium	87-110	lactotransferrin	Mus musculus	80-82
23582173-3	2013	Significantly, we demonstrate here that IL33 and ST2 are the primary early genes induced in the inflamed colon of BALB/c mice following dextran sulphate sodium (DSS)-induced experimental ulcerative colitis.	dextran sulphate sodium	136-159	interleukin 1 receptor-like 1	Mus musculus	49-52
23009282-1	2013	AIM: To compare the therapeutic effect of alpha(2) and alpha(4) integrin-blocking antibodies to conventional inflammatory bowel disease drugs methotrexate, 5-aminosalicylic acid and azathioprine in the dextran sulphate sodium mouse colitis model.	dextran sulphate sodium	202-225	immunoglobulin (CD79A) binding protein 1	Mus musculus	42-63
23785429-0	2013	Crucial role for CD69 in the pathogenesis of dextran sulphate sodium-induced colitis.	dextran sulphate sodium	45-68	CD69 antigen	Mus musculus	17-21
22848392-11	2012	In a comparative analysis we observed the PDZK1 downregulation also in the DSS (dextran sulphate sodium) model of colitis.	dextran sulphate sodium	80-103	PDZ domain containing 1	Mus musculus	42-47
22700475-0	2012	Intracolonically administered adeno-associated virus-bone morphogenetic protein-7 ameliorates dextran sulphate sodium-induced acute colitis in rats.	dextran sulphate sodium	94-117	bone morphogenetic protein 7	Rattus norvegicus	53-81
22569277-0	2013	Prophylactic effects of Lonicera japonica extract on dextran sulphate sodium-induced colitis in a mouse model by the inhibition of the Th1/Th17 response.	dextran sulphate sodium	53-76	negative elongation factor complex member C/D, Th1l	Mus musculus	135-138
22924972-2	2013	The purpose of this study was to further build on this evidence by examining the efficacy, mechanism and specificity of a potent, non-competitive and orally active C5a receptor (CD88) antagonist, PMX205, in the dextran sulphate sodium (DSS) model of murine innate colitis.	dextran sulphate sodium	211-234	hemolytic complement	Mus musculus	164-167
22924972-2	2013	The purpose of this study was to further build on this evidence by examining the efficacy, mechanism and specificity of a potent, non-competitive and orally active C5a receptor (CD88) antagonist, PMX205, in the dextran sulphate sodium (DSS) model of murine innate colitis.	dextran sulphate sodium	211-234	complement component 5a receptor 1	Mus musculus	178-182
22722030-1	2012	In the current study, we investigated the effect of the activation of the alpha-7 nicotinic acetylcholine receptor (alpha7 nAchR) on dextran sulphate sodium (DSS)-induced colitis and referred mechanical hyperalgesia in mice.	dextran sulphate sodium	133-156	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	74-114
22722030-1	2012	In the current study, we investigated the effect of the activation of the alpha-7 nicotinic acetylcholine receptor (alpha7 nAchR) on dextran sulphate sodium (DSS)-induced colitis and referred mechanical hyperalgesia in mice.	dextran sulphate sodium	133-156	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	116-128
21413942-0	2011	Dextran sulphate sodium increases splenic Gr1(+)CD11b(+) cells which accelerate recovery from colitis following intravenous transplantation.	dextran sulphate sodium	0-23	integrin subunit alpha M	Homo sapiens	48-53
21590770-0	2011	Role of miR-150-targeting c-Myb in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis.	dextran sulphate sodium	72-95	microRNA 150	Mus musculus	8-15
21590770-0	2011	Role of miR-150-targeting c-Myb in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis.	dextran sulphate sodium	72-95	myeloblastosis oncogene	Mus musculus	26-31