PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 23858977-7 2013 By in vitro experiments the absence of haemolytic activity of RBV tripalmitate-loaded PHEA-EDA-DPPE-GAL nanoparticles and their specificity toward HepG2 were demonstrated by using a competitive inhibition assay in the presence of free GAL and assessing nanoparticle uptake in the presence of free GAL and/or non-galactosylated nanoparticles. cyclohexenoesculetin-beta-galactoside 100-103 ectodysplasin A Homo sapiens 91-94 23557737-6 2013 Gal/GalNAc/Man3-core-bi-/tri-antennary-complex, Sia2-3Galbeta1-4GlcNAc, and high-mannose glycans were conjugated mainly to proteins from PN7 rd1 and PN14 wt retinae, respectively. cyclohexenoesculetin-beta-galactoside 0-3 phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide Mus musculus 141-144 23098908-3 2012 In the present study, the molar ratios of GalNAc or Gal to HP were analyzed for serum IgA from IgAN patients. cyclohexenoesculetin-beta-galactoside 42-45 CD79a molecule Homo sapiens 86-89 23243126-7 2012 Heterologously expressed and affinity-purified GALS1 could transfer Gal residues from UDP-Gal onto beta-1,4-galactopentaose. cyclohexenoesculetin-beta-galactoside 68-71 glycosyltransferase family protein (DUF23) Arabidopsis thaliana 47-52 23112793-7 2012 Furthermore, a GalR1-GalR2-5-HT1A heterotrimer is postulated to explain why only galanin (1-15) but not galanin (1-29) can antagonistically modulate the 5-HT1A receptors in the dorsal hippocampus rich in gal fragment binding sites. cyclohexenoesculetin-beta-galactoside 81-84 galanin receptor 1 Homo sapiens 15-20 22944432-2 2012 High-performance liquid chromatography (HPLC) identified that PTPa and PTPb was composed of Ara, Glc, Gal, Man and GlcUA in the proportion of 2.4:1.2:0.6:0.4:1.1 and 2.1:1.7:0.5:0.6:1.7, respectively. cyclohexenoesculetin-beta-galactoside 102-105 protein phosphatase 2 phosphatase activator Homo sapiens 62-66 22944432-2 2012 High-performance liquid chromatography (HPLC) identified that PTPa and PTPb was composed of Ara, Glc, Gal, Man and GlcUA in the proportion of 2.4:1.2:0.6:0.4:1.1 and 2.1:1.7:0.5:0.6:1.7, respectively. cyclohexenoesculetin-beta-galactoside 102-105 protein tyrosine phosphatase receptor type B Homo sapiens 71-75 22965229-3 2012 While searching for an enzyme responsible for the biosynthesis of Gal(alpha1-4)GalNAc, we identified a mutation in the A4GALT gene encoding Gb3/CD77 synthase (alpha1,4-galactosyltransferase). cyclohexenoesculetin-beta-galactoside 66-70 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 119-125 22965229-3 2012 While searching for an enzyme responsible for the biosynthesis of Gal(alpha1-4)GalNAc, we identified a mutation in the A4GALT gene encoding Gb3/CD77 synthase (alpha1,4-galactosyltransferase). cyclohexenoesculetin-beta-galactoside 66-70 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 140-143 22965229-3 2012 While searching for an enzyme responsible for the biosynthesis of Gal(alpha1-4)GalNAc, we identified a mutation in the A4GALT gene encoding Gb3/CD77 synthase (alpha1,4-galactosyltransferase). cyclohexenoesculetin-beta-galactoside 66-70 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 144-157 22965229-3 2012 While searching for an enzyme responsible for the biosynthesis of Gal(alpha1-4)GalNAc, we identified a mutation in the A4GALT gene encoding Gb3/CD77 synthase (alpha1,4-galactosyltransferase). cyclohexenoesculetin-beta-galactoside 66-70 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 159-189 23112793-7 2012 Furthermore, a GalR1-GalR2-5-HT1A heterotrimer is postulated to explain why only galanin (1-15) but not galanin (1-29) can antagonistically modulate the 5-HT1A receptors in the dorsal hippocampus rich in gal fragment binding sites. cyclohexenoesculetin-beta-galactoside 81-84 galanin receptor 2 Homo sapiens 21-26 23112793-7 2012 Furthermore, a GalR1-GalR2-5-HT1A heterotrimer is postulated to explain why only galanin (1-15) but not galanin (1-29) can antagonistically modulate the 5-HT1A receptors in the dorsal hippocampus rich in gal fragment binding sites. cyclohexenoesculetin-beta-galactoside 81-84 5-hydroxytryptamine receptor 1A Homo sapiens 27-33 22492969-2 2012 T-synthase (C1GALT1) transfers Gal to generate core 1 and core 2 mucin O-glycans; POFUT1 transfers O-fucose to particular epidermal growth factor-like repeats and is essential for canonical Notch signaling; and MGAT1 (GlcNAcT-I) transfers GlcNAc to initiate hybrid and complex N-glycan synthesis. cyclohexenoesculetin-beta-galactoside 31-34 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Homo sapiens 0-10 24750884-4 2012 GP-C1 consisted of Gal, Ara, Man, Rha, Glc, and GlcA in the proportions of 2.1:1.0:0.3:0.5:0.4:0.9. cyclohexenoesculetin-beta-galactoside 19-22 glypican 1 Homo sapiens 0-5 22492969-2 2012 T-synthase (C1GALT1) transfers Gal to generate core 1 and core 2 mucin O-glycans; POFUT1 transfers O-fucose to particular epidermal growth factor-like repeats and is essential for canonical Notch signaling; and MGAT1 (GlcNAcT-I) transfers GlcNAc to initiate hybrid and complex N-glycan synthesis. cyclohexenoesculetin-beta-galactoside 31-34 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Homo sapiens 12-19 21707612-7 2012 Analysis of hepatic gene expression showed that both conjugates significantly reduced Gal/LPS-mediated expression of chemoattractants, such as monocyte chemotactic protein 1 (MCP1) and RANTES. cyclohexenoesculetin-beta-galactoside 86-89 C-C motif chemokine ligand 2 Homo sapiens 143-173 22519357-3 2012 This work contains a modified dynamic model for GAL system in S. cerevisiae, which includes a novel mechanism for Gal3p activation upon induction with galactose. cyclohexenoesculetin-beta-galactoside 48-51 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 114-119 22519357-4 2012 The modification enables the model to simulate the experimental observation that in absence of galactose, oversynthesis of Gal3p can also induce the GAL system. cyclohexenoesculetin-beta-galactoside 149-152 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 123-128 21981750-5 2012 In contrast, ABO alloantibodies required a minimum trisaccharide Gal(NAc)alpha1-3(Fucalpha1-2)Gal epitope and recognize the elongated type-specific tetrasaccharides. cyclohexenoesculetin-beta-galactoside 65-68 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Homo sapiens 13-16 22107987-8 2012 COX inhibitors reduced the expression of TNF-alpha mRNA and the activity of NF-kappaB which were elevated by Gal/LPS treatment. cyclohexenoesculetin-beta-galactoside 109-112 tumor necrosis factor Mus musculus 41-50 21707612-7 2012 Analysis of hepatic gene expression showed that both conjugates significantly reduced Gal/LPS-mediated expression of chemoattractants, such as monocyte chemotactic protein 1 (MCP1) and RANTES. cyclohexenoesculetin-beta-galactoside 86-89 C-C motif chemokine ligand 2 Homo sapiens 175-179 21707612-7 2012 Analysis of hepatic gene expression showed that both conjugates significantly reduced Gal/LPS-mediated expression of chemoattractants, such as monocyte chemotactic protein 1 (MCP1) and RANTES. cyclohexenoesculetin-beta-galactoside 86-89 C-C motif chemokine ligand 5 Homo sapiens 185-191 22529896-0 2012 GalNAc/Gal-binding Rhizoctonia solani agglutinin has antiproliferative activity in Drosophila melanogaster S2 cells via MAPK and JAK/STAT signaling. cyclohexenoesculetin-beta-galactoside 0-3 hopscotch Drosophila melanogaster 129-132 23028834-11 2012 Similar adaptation features were found in our previous work when rewiring HIS3 to the GAL system and switching cells from galactose to glucose. cyclohexenoesculetin-beta-galactoside 86-89 imidazoleglycerol-phosphate dehydratase HIS3 Saccharomyces cerevisiae S288C 74-78 22529896-0 2012 GalNAc/Gal-binding Rhizoctonia solani agglutinin has antiproliferative activity in Drosophila melanogaster S2 cells via MAPK and JAK/STAT signaling. cyclohexenoesculetin-beta-galactoside 0-3 Signal-transducer and activator of transcription protein at 92E Drosophila melanogaster 133-137 23205153-3 2011 We present a dynamic model for GAL system in Saccharomyces cerevisiae, which includes a novel mechanism for Gal3p activation upon induction with galactose. cyclohexenoesculetin-beta-galactoside 31-34 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 108-113 23205153-4 2011 The modification enables the model to simulate the experimental observation that in absence of galactose, oversynthesis of Gal3p can also induce the GAL system. cyclohexenoesculetin-beta-galactoside 149-152 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 123-128 21561106-5 2011 We could show that hFcgammaRIIIa expressed by HEK cells was mostly bearing multifucosylated biantennary Asn162-glycans with a major fraction terminating with GalNAc residues replacing the more common Gal. cyclohexenoesculetin-beta-galactoside 158-161 Fc gamma receptor IIIa Homo sapiens 19-32 22379801-5 2011 METHODS: By using lactose as the main carbon source and X-Gal as chromogenic agent in the medium, cold-adapted strains producing beta-galactosidase were detected. cyclohexenoesculetin-beta-galactoside 58-61 galactosidase beta 1 Homo sapiens 129-147 21890741-1 2011 The yeast transcriptional activator Gal4 localizes to UAS(GAL) sites even in the absence of galactose but cannot activate transcription due to an association with the Gal80 protein. cyclohexenoesculetin-beta-galactoside 58-61 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 36-40 21753146-5 2011 Gal-1 and Gal-8 were both expressed during plasma cell differentiation, and both Gals promoted the formation of plasma cells. cyclohexenoesculetin-beta-galactoside 81-85 galectin 1 Homo sapiens 0-5 21753146-8 2011 Furthermore, synthetic type 1 LacNAcs that were able to block the binding of both Gals greatly reduced the effect of exogenously added recombinant Gal-1 and Gal-8 on promoting Ab production. cyclohexenoesculetin-beta-galactoside 82-86 galectin 1 Homo sapiens 147-152 21753146-8 2011 Furthermore, synthetic type 1 LacNAcs that were able to block the binding of both Gals greatly reduced the effect of exogenously added recombinant Gal-1 and Gal-8 on promoting Ab production. cyclohexenoesculetin-beta-galactoside 82-86 galectin 8 Homo sapiens 157-162 22233036-6 2011 GC analysis indicated that HM1, HM2, HM3, HM4 and HM41 were composed of Rha, Ara, Xyl, Man, Gal and Glc. cyclohexenoesculetin-beta-galactoside 92-95 cholinergic receptor muscarinic 1 Homo sapiens 27-30 22233036-6 2011 GC analysis indicated that HM1, HM2, HM3, HM4 and HM41 were composed of Rha, Ara, Xyl, Man, Gal and Glc. cyclohexenoesculetin-beta-galactoside 92-95 cholinergic receptor muscarinic 2 Homo sapiens 32-35 22233036-6 2011 GC analysis indicated that HM1, HM2, HM3, HM4 and HM41 were composed of Rha, Ara, Xyl, Man, Gal and Glc. cyclohexenoesculetin-beta-galactoside 92-95 cholinergic receptor muscarinic 3 Homo sapiens 37-40 22233036-6 2011 GC analysis indicated that HM1, HM2, HM3, HM4 and HM41 were composed of Rha, Ara, Xyl, Man, Gal and Glc. cyclohexenoesculetin-beta-galactoside 92-95 cholinergic receptor muscarinic 4 Homo sapiens 42-45 21146503-11 2011 OL-GAL was found as potent as galardin (K(i) equal to 1.8nM for OL-GAL and 1.45nM for GAL) and selectivity for that MMP was attained (2-3 log orders of difference in inhibitory potency as compared to other MMPs). cyclohexenoesculetin-beta-galactoside 3-6 matrix metallopeptidase 2 Homo sapiens 206-210 20439727-5 2010 The enzyme T-synthase transfers Gal to GalNAcalpha1-Ser/Thr to form the core 1 structure Galbeta1-3GalNAcalpha1-Ser/Thr, a precursor for core 2 and extended core 1 O-glycans that might serve as selectin ligands. cyclohexenoesculetin-beta-galactoside 32-35 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 Mus musculus 11-21 20644332-6 2010 To further explore the effect of SirT1 activation on oxidative stress-induced aging, senescence-associated beta-galactosidase (SA-beta-gal) expression in RV-treated human umbilical vein endothelial cells (HUVECs) with or without H(2)O(2) treatment was evaluated. cyclohexenoesculetin-beta-galactoside 112-115 SH3 domain binding protein 5 Homo sapiens 127-134 19726412-0 2010 Bulbar involvement in patients with antiganglioside antibodies against NeuNAc(alpha2-3)Gal. cyclohexenoesculetin-beta-galactoside 87-90 immunoglobulin kappa variable 2-24 Homo sapiens 71-86 19726412-1 2010 BACKGROUND: Reactivity against terminal NeuNAc(alpha2-3)Gal, common to several gangliosides such as GD1a, GT1b and GM3, has rarely been reported. cyclohexenoesculetin-beta-galactoside 56-59 immunoglobulin kappa variable 2-24 Homo sapiens 40-55 19726412-3 2010 The authors suggested a correlation between NeuNAc(alpha2-3)Gal reactivity and bulbar involvement. cyclohexenoesculetin-beta-galactoside 60-63 immunoglobulin kappa variable 2-24 Homo sapiens 44-59 19726412-7 2010 RESULTS: Reactivity against NeuNAc(alpha2-3)Gal, shared by GM3, GD1a and GT1b gangliosides, was detected in 10 patients: isolated in one patient, and concomitant with reactivity against other gangliosides in the remaining patients. cyclohexenoesculetin-beta-galactoside 44-47 immunoglobulin kappa variable 2-24 Homo sapiens 28-43 19726412-10 2010 CONCLUSIONS: Reactivity against the NeuNAc(alpha2-3)Gal epitope is rare and is generally found in association with reactivity against the disialosyl epitope. cyclohexenoesculetin-beta-galactoside 52-55 immunoglobulin kappa variable 2-24 Homo sapiens 36-51 20572145-3 2010 3,4-Cyclohexenoesculetin beta-D-galactopyranoside (S-Gal) is a commercial histologic stain, which forms a black precipitate in the presence of beta-gal and ferric ions, suggesting potential detectability by MRI. cyclohexenoesculetin-beta-galactoside 0-49 galactosidase beta 1 Homo sapiens 143-151 20572145-3 2010 3,4-Cyclohexenoesculetin beta-D-galactopyranoside (S-Gal) is a commercial histologic stain, which forms a black precipitate in the presence of beta-gal and ferric ions, suggesting potential detectability by MRI. cyclohexenoesculetin-beta-galactoside 51-56 galactosidase beta 1 Homo sapiens 143-151 20336366-2 2010 The Xyl can be modified by 2-O-phosphate in both CS and HS, whereas the Gal residues can be sulfated at C-4 and/or C-6 in CS but not in HS. cyclohexenoesculetin-beta-galactoside 72-75 complement component C6 Cricetulus griseus 115-118 19887452-3 2010 Ionizing radiation (IR) causes activation of ERK, in turn generating intracellular reactive oxygen species (ROS) with induction of senescence-associated beta-galactosidase (SA-beta-gal) activity. cyclohexenoesculetin-beta-galactoside 157-161 mitogen-activated protein kinase 1 Homo sapiens 45-48 19887452-3 2010 Ionizing radiation (IR) causes activation of ERK, in turn generating intracellular reactive oxygen species (ROS) with induction of senescence-associated beta-galactosidase (SA-beta-gal) activity. cyclohexenoesculetin-beta-galactoside 157-161 SH3 domain binding protein 5 Homo sapiens 173-180 19508952-5 2009 Several tungstate-type PMs inhibited Gal: alpha2,3-sialyltransferase-I (ST3Gal-I) activity at sub-nanomolar levels. cyclohexenoesculetin-beta-galactoside 37-40 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 Homo sapiens 72-80 20816162-5 2010 T-synthase activity is commonly measured by its ability to transfer [3H]Gal from UDP-[3H]Gal to an artificial acceptor GalNAcalpha-1-O-phenyl to form [3H]Galbeta1-3GalNAcalpha-1-O-phenyl, which can then be isolated and quantified. cyclohexenoesculetin-beta-galactoside 72-75 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Homo sapiens 0-10 20807639-3 2010 Glucuronyl transfer to the Gal residue, the final biosynthetic step in the common linkage region, is catalyzed by a key enzyme, beta1,3-glucuronyltransferase, which is termed glucuronyltransferase I (GlcAT-I). cyclohexenoesculetin-beta-galactoside 27-30 beta-1,3-glucuronyltransferase 3 Homo sapiens 200-207 20149189-13 2010 CONCLUSION: It is possible that the T-antigen and Tn-antigen related to GalNAc are non-Gal antigens, but, fortunately, not only alpha-Gal but also GalNAc were found to be decreased in the KO-pig. cyclohexenoesculetin-beta-galactoside 72-75 GLA Sus scrofa 128-137 20387497-7 2009 CONCLUSION: By injecting of 50% CCl4 olive solution intraperitoneally, acute-on-chronic liver failure model could be induced by D-gal, LPS/D-gal in rats. cyclohexenoesculetin-beta-galactoside 130-133 C-C motif chemokine ligand 4 Rattus norvegicus 32-36 19540883-5 2009 In contrast, N-glycan with Gal (21.3%) and GlcNAc (16.2%) terminal residues linked to Manalpha(1,3) branch were detected on beta3GnT2 expressed in silkworm larvae. cyclohexenoesculetin-beta-galactoside 27-30 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 124-133 19500344-12 2009 Asialoglycopolypeptide was regioselectively and quantitatively sialylated by catalytic reaction at the terminal Gal residue to obtain alpha2,6-sialoglycopolypeptide using ST6Gal1. cyclohexenoesculetin-beta-galactoside 112-115 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 Rattus norvegicus 171-178 19245254-3 2009 The alpha3Gal-T enzyme belongs to the alpha3Gal/GalNAc-T family that includes human blood group A and B glycosyltransferases, which transfer GalNAc and Gal, respectively, to the Gal moiety of the trisaccharide Fucalpha1-2Galbeta1-4GlcNAc. cyclohexenoesculetin-beta-galactoside 10-13 beta-1,4-N-acetyl-galactosaminyltransferase 1 Homo sapiens 48-56 19332879-5 2009 Of the 8 proteins tested, only Mre11 was unable to cause DSBs even though it binds to UAS(GAL) at GAL2. cyclohexenoesculetin-beta-galactoside 90-93 MRX complex nuclease subunit Saccharomyces cerevisiae S288C 31-36 19332879-5 2009 Of the 8 proteins tested, only Mre11 was unable to cause DSBs even though it binds to UAS(GAL) at GAL2. cyclohexenoesculetin-beta-galactoside 90-93 galactose permease GAL2 Saccharomyces cerevisiae S288C 98-102 19245254-3 2009 The alpha3Gal-T enzyme belongs to the alpha3Gal/GalNAc-T family that includes human blood group A and B glycosyltransferases, which transfer GalNAc and Gal, respectively, to the Gal moiety of the trisaccharide Fucalpha1-2Galbeta1-4GlcNAc. cyclohexenoesculetin-beta-galactoside 44-47 beta-1,4-N-acetyl-galactosaminyltransferase 1 Homo sapiens 48-56 18824562-1 2008 T antigen (Galbeta1-3GalNAcalpha1-Ser/Thr), the well-known tumor-associated antigen, is a core 1 mucin-type O-glycan structure that is synthesized by core 1 beta1,3-galactosyltransferase (C1beta3GalT), which transfers Gal from UDP-Gal to Tn antigen (GalNAcalpha1-Ser/Thr). cyclohexenoesculetin-beta-galactoside 11-14 Core 1 Galactosyltransferase A Drosophila melanogaster 150-186 18946736-5 2008 Livers of galactosamine/lipopolysaccharide (Gal/LPS)-exposed Fas wild-type mice highly expressed both Fas and FasL and revealed marked hepatocellular apoptosis that was almost completely blocked by soluble TNFalpha-receptor; this was also almost absent in Gal/LPS-exposed Fas lymphoproliferation mutant mice. cyclohexenoesculetin-beta-galactoside 44-47 tumor necrosis factor Mus musculus 206-214 18824562-1 2008 T antigen (Galbeta1-3GalNAcalpha1-Ser/Thr), the well-known tumor-associated antigen, is a core 1 mucin-type O-glycan structure that is synthesized by core 1 beta1,3-galactosyltransferase (C1beta3GalT), which transfers Gal from UDP-Gal to Tn antigen (GalNAcalpha1-Ser/Thr). cyclohexenoesculetin-beta-galactoside 11-14 Core 1 Galactosyltransferase A Drosophila melanogaster 188-199 18834968-1 2008 Lysyl hydroxylase 3 (LH3, encoded by PLOD3) is a multifunctional enzyme capable of catalyzing hydroxylation of lysyl residues and O-glycosylation of hydroxylysyl residues producing either monosaccharide (Gal) or disaccharide (Glc-Gal) derivatives, reactions that form part of the many posttranslational modifications required during collagen biosynthesis. cyclohexenoesculetin-beta-galactoside 204-207 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 Homo sapiens 0-19 19014615-4 2008 In the GAL regulatory system of Saccharomyces cerevisiae, the inhibition of glucose is accomplished through two regulatory mechanisms: one through the transcriptional repressor Mig1p, and the other through regulating the amount of transcriptional activator Gal4p. cyclohexenoesculetin-beta-galactoside 7-10 transcription factor MIG1 Saccharomyces cerevisiae S288C 177-182 19014615-4 2008 In the GAL regulatory system of Saccharomyces cerevisiae, the inhibition of glucose is accomplished through two regulatory mechanisms: one through the transcriptional repressor Mig1p, and the other through regulating the amount of transcriptional activator Gal4p. cyclohexenoesculetin-beta-galactoside 7-10 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 257-262 18834968-1 2008 Lysyl hydroxylase 3 (LH3, encoded by PLOD3) is a multifunctional enzyme capable of catalyzing hydroxylation of lysyl residues and O-glycosylation of hydroxylysyl residues producing either monosaccharide (Gal) or disaccharide (Glc-Gal) derivatives, reactions that form part of the many posttranslational modifications required during collagen biosynthesis. cyclohexenoesculetin-beta-galactoside 204-207 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 Homo sapiens 21-24 18834968-1 2008 Lysyl hydroxylase 3 (LH3, encoded by PLOD3) is a multifunctional enzyme capable of catalyzing hydroxylation of lysyl residues and O-glycosylation of hydroxylysyl residues producing either monosaccharide (Gal) or disaccharide (Glc-Gal) derivatives, reactions that form part of the many posttranslational modifications required during collagen biosynthesis. cyclohexenoesculetin-beta-galactoside 204-207 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 Homo sapiens 37-42 18358727-0 2008 Trivalent, Gal/GalNAc-containing ligands designed for the asialoglycoprotein receptor. cyclohexenoesculetin-beta-galactoside 11-14 asialoglycoprotein receptor 1 Homo sapiens 58-85 17916362-9 2007 Conversely, overexpression of Sirt1 prevented hydrogen peroxide-induced SA-beta-gal activity, morphological changes and deranged expression of PAI-1 and eNOS. cyclohexenoesculetin-beta-galactoside 80-83 sirtuin 1 Homo sapiens 30-35 17905738-10 2007 p30 associates with gp900 and gp40, Gal/GalNAc-containing mucin-like glycoproteins that are also implicated in mediating infection. cyclohexenoesculetin-beta-galactoside 36-39 centromere protein V Homo sapiens 0-3 17083333-7 2007 Moreover, the combination of the GALR3 rs3,091,367 risk allele and GAL risk haplotypes led to a modestly increased odds ratio (OR) for alcoholism (2.4) as compared with the effect of either GAL (1.9) or GALR3 alone (1.4). cyclohexenoesculetin-beta-galactoside 33-36 galanin receptor 3 Homo sapiens 203-208 17680779-2 2007 A TBP1(E186D) mutation had been described that affected interaction of Tbp1p with TFIIB (transcription factor IIB) and that caused slow-growth, temperature-sensitivity, 3-aminotriazole-sensitivity as well as a gal(-) phenotype. cyclohexenoesculetin-beta-galactoside 210-213 EGFLAM antisense RNA 3 Homo sapiens 2-7 17661401-5 2007 X-Gal staining of Foxl1-Cre; Rosa26R bi-transgenic lines confirm that Foxl1-Cre results in recombination specifically in the gastrointestinal mesenchyme. cyclohexenoesculetin-beta-galactoside 2-5 forkhead box L1 Mus musculus 18-23 17661401-5 2007 X-Gal staining of Foxl1-Cre; Rosa26R bi-transgenic lines confirm that Foxl1-Cre results in recombination specifically in the gastrointestinal mesenchyme. cyclohexenoesculetin-beta-galactoside 2-5 forkhead box L1 Mus musculus 70-75 17341689-5 2007 EPs interaction with S-Gal triggered NO release and activation of PI3-kinase/Akt and ERK1/2 in human coronary endothelial cells (HCAECs) and rat neonatal cardiomyocytes (RCs). cyclohexenoesculetin-beta-galactoside 21-26 AKT serine/threonine kinase 1 Homo sapiens 77-80 17341689-5 2007 EPs interaction with S-Gal triggered NO release and activation of PI3-kinase/Akt and ERK1/2 in human coronary endothelial cells (HCAECs) and rat neonatal cardiomyocytes (RCs). cyclohexenoesculetin-beta-galactoside 21-26 mitogen-activated protein kinase 3 Homo sapiens 85-91 17463158-11 2007 Immunohistochemistry demonstrated that HNF-4alpha depletion in the liver is associated with d-Gal sensitization but not TNF-alpha treatment. cyclohexenoesculetin-beta-galactoside 94-97 hepatic nuclear factor 4, alpha Mus musculus 39-49 17452322-3 2007 Here, we investigated the cellular function of the single galactokinase GAL1 in the multicellular ascomycete Hypocrea jecorina (=Trichoderma reesei) in the induction of the gal genes and of the galactokinase-dependent induction of the cellulase genes by lactose (1,4-O-beta-D-galactopyranosyl-D-glucose). cyclohexenoesculetin-beta-galactoside 58-61 galactokinase Saccharomyces cerevisiae S288C 72-76 16818789-8 2006 Purified Galectin-3 is able to bind directly to Gal-alpha(1,3)Gal-beta(1,4)GlcNAc-R. Galectin-3 can also be affinity isolated from monocytes (and not lymphocytes) using an Gal-alpha(1,3)Gal-beta(1,4)GlcNAc-R-biotin/streptavidin-bead pull-down system. cyclohexenoesculetin-beta-galactoside 9-12 galectin 3 Homo sapiens 85-95 17388629-1 2007 In our efforts to design new anti-cancer vaccines based on the tumor associated carbohydrate antigen dimeric Lex, we have synthesized the fragment GlcNAc-beta-(1-->3)-Gal-beta-(1-->4)-GlcNAc-beta-(1-->O)-Me. cyclohexenoesculetin-beta-galactoside 170-173 fucosyltransferase 4 Homo sapiens 109-112 17400811-3 2007 Ultrasonography revealed a significantly reduced atherosclerotic plaque area in abdominal aortas of rabbits infected through intima with Ad-APN, by 35.2% compared with the area before treatment (P < 0.01), and by 35.8% compared with that in Ad-beta gal-treated rabbits (P < 0.01). cyclohexenoesculetin-beta-galactoside 252-255 aminopeptidase N Oryctolagus cuniculus 140-143 17121853-5 2007 Gal80p, the focus of this investigation, plays a pivotal role both in terms of repressing the activity of Gal4p and allowing the GAL switch to respond to galactose. cyclohexenoesculetin-beta-galactoside 129-132 transcription regulator GAL80 Saccharomyces cerevisiae S288C 0-6 16903855-3 2006 The effects of coinjections of GAL(1-29) and the NPY Y(1) agonist on the expression of c-FOS immunoreactivity in the NTS were also studied. cyclohexenoesculetin-beta-galactoside 31-34 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 87-92 16300412-11 2005 (vi) A 3- or 4-fluoro substituent in beta1,4Gal resulted in poor acceptors for the cloned alpha2,6(N)ST and alpha2,3(N)ST, whereas 4-fluoro- or 4-OMe-Galbeta1,3GalNAcalpha was a good acceptor for cloned alpha2,3(O)ST. (vii) 4-O-Methylation of beta1,4Gal abolished the acceptor ability toward alpha2,6(N)ST but increased the acceptor efficiency considerably toward alpha2,3(N)ST. (viii) Just like LNCaPalpha1,2-FT and Gal-3-O-sulfotransferase T2, the cloned alpha2,3(N)ST which modifies terminal Gal in Galbeta1,4GlcNAc also efficiently utilizes the terminal beta1,3Gal in the Globo backbone. cyclohexenoesculetin-beta-galactoside 44-47 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 153-160 16463070-6 2006 Six out of the eight studied Gal-4/UAS-IP3K1 hybrids displayed abnormal behavioral responses to ethyl acetate, acetone, ethanol or propionaldehyde. cyclohexenoesculetin-beta-galactoside 29-32 Inositol 1,4,5-triphosphate kinase 1 Drosophila melanogaster 39-44 16419090-2 2006 Here we report 6-chloro-3-indoxyl-beta-D-galactopyranoside (S-gal) is more sensitive for beta-gal activity than 5-bromo-4-chloro-3-indolyl-beta-D-galactoside (X-gal), particularly during the early developmental stages of mouse embryos. cyclohexenoesculetin-beta-galactoside 60-65 galactosidase, beta 1 Mus musculus 89-97 17113876-1 2006 The biosynthesis of the core 1 O-glycan (Galbeta1-3GalNAcalpha1-Ser/Thr, T antigen) is controlled by core 1 beta1-3-galactosyltransferase (T-synthase), which catalyzes the addition of Gal to GalNAcalpha1-Ser/Thr (Tn antigen). cyclohexenoesculetin-beta-galactoside 41-44 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 Mus musculus 139-149 16670683-4 2006 In this review, we provide an updated account of Gal4 function, including data from new technologies that have been recently applied to the study of the GAL network. cyclohexenoesculetin-beta-galactoside 153-156 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 49-53 16288808-3 2006 Here, all possible recognition factors of RCA1 of glycan binding were examined by enzyme-linked lectinosorbent (ELLSA) and inhibition assays, using known mammalian Gal/GalNAc carbohydrate structural units and natural polyvalent glycans. cyclohexenoesculetin-beta-galactoside 164-167 von Hippel-Lindau tumor suppressor Homo sapiens 42-46 16326711-1 2006 The human ABO(H) blood group A and B antigens are generated by the homologous glycosyltransferases A (GTA) and B (GTB), which add the monosaccharides GalNAc and Gal, respectively, to the cell-surface H antigens. cyclohexenoesculetin-beta-galactoside 150-153 integrin subunit alpha 2b Homo sapiens 78-112 16326711-5 2006 Furthermore, these structures show that acceptor recognition is dominated by the central Gal residue despite the fact that the L-Fuc residue is required for efficient catalysis and give direct insight into the design of model inhibitors for GTA and GTB. cyclohexenoesculetin-beta-galactoside 89-92 integrin subunit alpha 2b Homo sapiens 241-244 16273243-7 2005 beta-galactosidase expression was measured by X-Gal staining in 7.0% of HMG, 17.0% of HOSM-1 and 11.5% of HOSM-2 cells. cyclohexenoesculetin-beta-galactoside 48-51 galactosidase beta 1 Homo sapiens 0-18 15979597-12 2005 Araf residues were attached to C-3 of alpha-L-(1-->5)-Araf chains and to C-4 of Gal residues. cyclohexenoesculetin-beta-galactoside 83-86 complement C4A (Rodgers blood group) Homo sapiens 76-79 15858075-6 2005 alpha1-Acid glycoprotein (a positive AP protein), alpha1-macroglobulin (a non-AP protein), and alpha1-inhibitor3 (a negative AP protein) also show similar alterations in NeuAc/Gal ratio and decreases in Fuc. cyclohexenoesculetin-beta-galactoside 176-179 pregnancy-zone protein Rattus norvegicus 50-70 15858075-6 2005 alpha1-Acid glycoprotein (a positive AP protein), alpha1-macroglobulin (a non-AP protein), and alpha1-inhibitor3 (a negative AP protein) also show similar alterations in NeuAc/Gal ratio and decreases in Fuc. cyclohexenoesculetin-beta-galactoside 176-179 alpha-1-inhibitor III Rattus norvegicus 95-112 15979597-9 2005 The Rha located in the rhamnogalacturonan core was branched randomly by Gal units. cyclohexenoesculetin-beta-galactoside 72-75 HCL2 Homo sapiens 4-7 15736931-2 2005 Comparison of the crystal structures of UDP-Gal- and UDP-Glc-bound beta4Gal-T1 reveals that the O4 hydroxyl group in both Gal and Glc moieties forms a hydrogen bond with the side chain carboxylate group of Glu317. cyclohexenoesculetin-beta-galactoside 44-47 beta-1,4-galactosyltransferase 1 Bos taurus 67-78 15979597-12 2005 Araf residues were attached to C-3 of alpha-L-(1-->5)-Araf chains and to C-4 of Gal residues. cyclohexenoesculetin-beta-galactoside 83-86 A-Raf proto-oncogene, serine/threonine kinase Homo sapiens 0-4 15947941-1 2005 Staining by 5-bromo-4-chloro-3-indolyl-beta-D: -galactopyranoside (X-gal) typically detects activity of E. coli beta-galactosidase (beta-gal) in transduced tissues that express the LacZ reporter gene. cyclohexenoesculetin-beta-galactoside 48-51 galactosidase, beta 1 Mus musculus 112-130 15680479-3 2005 Anesthesized male Sprague-Dawley rats received intracisternal microinjections of Ang II (3 nmol) with GAL(1-29) (3 nmol) or GAL(1-15) (0.1 nmol) alone or in combination. cyclohexenoesculetin-beta-galactoside 102-105 angiogenin Rattus norvegicus 81-84 15680479-9 2005 The coinjections of Ang II with GAL(1-15) induced an increase in HR not significantly different from the tachycardia produced by each peptide. cyclohexenoesculetin-beta-galactoside 32-35 angiogenin Rattus norvegicus 20-23 15680479-12 2005 The coinjections of Ang II with GAL(1-29) and with DuP 753 restored the transient vasopressor effect produced by GAL(1-29). cyclohexenoesculetin-beta-galactoside 32-35 angiogenin Rattus norvegicus 20-23 15812240-4 2005 Our study suggested that compared with the human alpha 1,2 fucosyltransferase (FT) gene and the porcine antisense alpha 1,3 galactosyltransferase gene, sequence-specific siRNA targeting Gal was capable of suppressing Gal expression markedly, and therefore, significantly inhibiting xenoreactivity and the complement activation with human serum in PIEC cells. cyclohexenoesculetin-beta-galactoside 186-189 fucosyltransferase 2 Homo sapiens 49-77 15736931-7 2005 This alternate conformation now causes a steric hindrance to the O4 hydroxyl group of the Gal moiety of UDP-Gal, probably causing the dissociation of UDP-Gal and the reduced k(cat) of the Gal-T reaction. cyclohexenoesculetin-beta-galactoside 90-93 galactose-1-phosphate uridylyltransferase Bos taurus 188-193 15537482-8 2004 Mean change in ADAS-cog at 6 months was -1.5 (95% confidence interval -2.2, -0.8, p < 0.001) for GAL and +0.2 (-0.6, 0.9, p = 0.72) for PLAC. cyclohexenoesculetin-beta-galactoside 97-100 alkylglycerone phosphate synthase Homo sapiens 15-19 15479235-7 2004 We demonstrate the methodology using the GAL system of Saccharomyces cerevisiae for which the steady-state analysis reveals that Gal3p neither dimerizes nor shuttles between the cytoplasm and the nucleus. cyclohexenoesculetin-beta-galactoside 41-44 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 129-134 15209540-5 2004 Moreover, the marked age-related increase in structures Man (alpha1-2, alpha1-3, alpha1-6) Man, Fuc (alpha1-6) GlcNAc as well as Gal (beta1-3) GlcNAc was observed, whereas staining with terminal NeuAc and GlcNAc showed an inverse correlation. cyclohexenoesculetin-beta-galactoside 129-132 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 134-141 15123291-8 2004 The activity of MCL was not inhibited by the presence of monosaccharides, such as Man, Fuc, Gal, Glc, GlcNAc, and NeuNAc. cyclohexenoesculetin-beta-galactoside 92-95 C-type lectin domain family 4 member D Homo sapiens 16-19 14745002-1 2004 The core 1 beta1-3-galactosyltransferase (T-synthase) transfers Gal from UDP-Gal to GalNAcalpha1-Ser/Thr (Tn antigen) to form the core 1 O-glycan Galbeta1-3GalNAcalpha1-Ser/Thr (T antigen). cyclohexenoesculetin-beta-galactoside 64-67 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 Mus musculus 42-52 15223322-2 2004 We report a 1.9A resolution crystal structure of the Fab of a humanized antibody (hu3S193) in complex with the Le(y) tetrasaccharide, Fuc(alpha 1-->2)Gal(beta 1-->4)[Fuc(alpha 1-->3)]GlcNAc. cyclohexenoesculetin-beta-galactoside 153-156 FA complementation group B Homo sapiens 53-56 15123660-3 2004 A cytosolic extract from Dictyostelium was found to yield, after 2400-fold purification, an activity that could transfer Gal from UDP-Gal to both a Fuc-terminated glycoform of Skp1 and synthetic Fuc conjugates in the presence of Mn(2+) and dithiothreitol. cyclohexenoesculetin-beta-galactoside 121-124 S-phase kinase associated protein 1 Homo sapiens 176-180 15121195-5 2004 The reducing end core (Gal/GlcNAcbeta1-3GalNAcol or Gal/GlcNAcbeta1-3(GlcNAcbeta1-6)GalNAcol) could be deduced from the pronounced glycosidic C-3 cleavage and A(i) type cleavages of the reducing end GalNAcol, together with the non reducing end fragment from the loss of a single substituted GalNAcol. cyclohexenoesculetin-beta-galactoside 23-26 complement C3 Homo sapiens 142-145 15121195-5 2004 The reducing end core (Gal/GlcNAcbeta1-3GalNAcol or Gal/GlcNAcbeta1-3(GlcNAcbeta1-6)GalNAcol) could be deduced from the pronounced glycosidic C-3 cleavage and A(i) type cleavages of the reducing end GalNAcol, together with the non reducing end fragment from the loss of a single substituted GalNAcol. cyclohexenoesculetin-beta-galactoside 40-43 complement C3 Homo sapiens 142-145 14693272-4 2003 X-gal staining of cells exposed to Ad5-lacZ showed that the adenoviral vector was capable of transducing each of the cell lines. cyclohexenoesculetin-beta-galactoside 2-5 Alzheimer disease, familial, type 5 Homo sapiens 35-38 12874307-2 2003 One of the Fab clones, CP33, recognized the 260-kDa galactose- and N-acetyl-D-galactosamine (Gal/GalNAc)-specific lectin of E. histolytica. cyclohexenoesculetin-beta-galactoside 93-96 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 23-27 12847091-6 2003 Enzymatic analysis of the transferase reaction products showed that D4ST-1 far more efficiently transferred sulfate to GalNAc residues in -IdoUA-Gal-NAc-IdoUA-than in -GlcUA-GalNAc-GlcUA-sequences. cyclohexenoesculetin-beta-galactoside 119-122 carbohydrate sulfotransferase 14 Homo sapiens 68-74 12847091-8 2003 Structural analysis of the oligosaccharides, which were isolated after chondroitinase AC-I digestion of the 35S-labeled transferase reaction products, revealed for the first time that D4ST-1, as compared with C4ST-1 and C4ST-2, most efficiently utilized GalNAc residues located not only in the sequence -IdoUA-GalNAc-IdoUA- but also in -GlcUA-Gal-NAc-IdoUA- and -IdoUA-GalNAc-GlcUA-. cyclohexenoesculetin-beta-galactoside 254-257 carbohydrate sulfotransferase 14 Homo sapiens 184-190 12854954-2 2003 However, in the presence of alpha-lactalbumin (LA) it transfers Gal to glucose (Glc) instead to GlcNAc. cyclohexenoesculetin-beta-galactoside 64-67 lactalbumin alpha Homo sapiens 28-45 12854954-2 2003 However, in the presence of alpha-lactalbumin (LA) it transfers Gal to glucose (Glc) instead to GlcNAc. cyclohexenoesculetin-beta-galactoside 64-67 lactalbumin alpha Homo sapiens 47-49 12511570-6 2003 Strikingly, DmGlcAT-I has specificity for Galbeta1-3Galbeta1-4Xyl, whereas DmGlcAT-BSI and DmGlcAT-BSII act on a wide array of substrates with non-reducing terminal beta1,3- and beta1,4-linked Gal residues. cyclohexenoesculetin-beta-galactoside 42-45 Glucuronyltransferase I Drosophila melanogaster 12-21 12653996-9 2003 The average distance between the two domains in CRP-DNA complexes, possessing lac, gal or ICAP sequences, shows an increase, as evidenced by the increase in the average distance between Cys178 and Trp85 to approximately 20 A. cyclohexenoesculetin-beta-galactoside 83-86 catabolite gene activator protein Escherichia coli 48-51 12626393-0 2003 Purification and cDNA cloning of UDP-GlcNAc:GlcNAcbeta1-3Galbeta1-4Glc(NAc)-R [GlcNAc to Gal]beta1,6N-acetylglucosaminyltransferase from rat small intestine: a major carrier of dIGnT activity in rat small intestine. cyclohexenoesculetin-beta-galactoside 57-60 glucosaminyl (N-acetyl) transferase 1 Rattus norvegicus 93-131 12536147-4 2003 As soon as either the Reb1p-binding site or the UAS(GAL) or both are mutated, nucleosomes slip into the promoter of GCY1 paralleled by a reduction of basal transcription activity to about 30% in either single mutant and to <10% in the double mutant. cyclohexenoesculetin-beta-galactoside 52-55 glycerol 2-dehydrogenase (NADP(+)) GCY1 Saccharomyces cerevisiae S288C 116-120 11971859-10 2002 Further, D-Fucbeta1,3Gal-NAcbeta1,3Galalpha-O-Me was a very efficient acceptor, indicating that the C-6 hydroxyl group of the terminal Gal moiety in Globo H is not essential for the enzyme activity. cyclohexenoesculetin-beta-galactoside 21-24 complement C6 Homo sapiens 100-103 11916963-2 2002 In the presence of alpha-lactalbumin (LA), the Gal acceptor specificity is altered from GlcNAc to Glc. cyclohexenoesculetin-beta-galactoside 47-50 lactalbumin alpha Homo sapiens 19-36 11909595-1 2002 A potential tetrasaccharide ligand for E-selectin, (Na(+-)O(3)SO-3)Galbeta-(1-->4)[Fucalpha-(1-->3)]Glcbeta-(1-->6)Gal, an analogue of the ovarian cystadenoma glycoprotein tetrasaccharide fragment, was synthesized in a highly practical way. cyclohexenoesculetin-beta-galactoside 67-70 selectin E Homo sapiens 39-49 12636412-1 2003 A practical sequence is described for converting d-glucosamine into peracetylated Gal(beta-1,4)GlcNTroc(beta1-S)Ph and Neu5Ac(alpha-2,3)Gal(beta-1,4)GlcNTroc(beta1-S)Ph building blocks using a synthetic strategy based on chemoenzymatic oligosaccharide synthesis. cyclohexenoesculetin-beta-galactoside 82-86 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 140-146 12444972-4 2002 Disruption of MRG19 in a gal3 background (this strain shows long-term adaptation phenotype) further delays the GAL induction, supporting the notion that its function is important only under low inducing signals. cyclohexenoesculetin-beta-galactoside 111-114 Csr2p Saccharomyces cerevisiae S288C 14-19 11980897-3 2002 The recombinant soluble form of ST8Sia VI expressed in COS-7 cells exhibited alpha2,8-sialyltransferase activity toward both glycolipids and glycoproteins that have the NeuAcalpha2,3(6)Gal sequence at the nonreducing end of their carbohydrate groups. cyclohexenoesculetin-beta-galactoside 185-188 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Mus musculus 32-41 11980897-7 2002 ST8Sia VI also exhibited activity toward oligosaccharides such as sialyllactose and sialyllactosamine, and the structure of the minimal acceptor substrate for ST8Sia VI was determined as the NeuAcalpha2,3(6)Gal sequence. cyclohexenoesculetin-beta-galactoside 207-210 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Mus musculus 0-9 11980897-7 2002 ST8Sia VI also exhibited activity toward oligosaccharides such as sialyllactose and sialyllactosamine, and the structure of the minimal acceptor substrate for ST8Sia VI was determined as the NeuAcalpha2,3(6)Gal sequence. cyclohexenoesculetin-beta-galactoside 207-210 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Mus musculus 159-168 12815232-6 2002 Fluorescence-activated cell cytometry of different CHO glycosylation mutants and western blotting after glycosidase treatments were used to show that anti-LEC10 cell antisera from Mgat3(-/-) mice recognize cellular glycoproteins with complex N-glycans containing both a bisecting GlcNAc and Gal residues. cyclohexenoesculetin-beta-galactoside 291-294 mannoside acetylglucosaminyltransferase 3 Mus musculus 180-185 11866878-4 2002 RESULTS: SC4 was a highly branched polysaccharide with mean molecular weight of 4.5 10(5), composed of Rha, Xyl, Ser, Gal, and GalA in the molar ratio of 1.0 7.0 5.3 1.2 4.2. cyclohexenoesculetin-beta-galactoside 118-121 secretory carrier membrane protein 4 Mus musculus 9-12 11677243-2 2002 Core 1 is synthesized by the transfer of Gal from UDP-Gal to GalNAcalpha1-R by core 1 beta3-galactosyltransferase (core 1 beta3-Gal-T). cyclohexenoesculetin-beta-galactoside 41-44 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 Rattus norvegicus 115-133 11707585-7 2001 Of six beta 4galactosyltransferases (beta 4GalT) in Chinese hamster ovary cells, only beta 4GalT-1 is required to add Gal to GlcNAc beta 3Fuc, identifying beta 4GalT-1 as a new modulator of Notch signaling. cyclohexenoesculetin-beta-galactoside 43-46 beta-1,4-galactosyltransferase 1 Cricetulus griseus 86-98 11502266-7 2001 Alpha-lactalbumin (alpha-LA) inhibited up to 85%, the transfer of Gal to the GlcNAc moiety linked either to Man or GlcNAc. cyclohexenoesculetin-beta-galactoside 66-69 lactalbumin alpha Homo sapiens 0-17 11479316-9 2001 We also show that the CS chain of appican contains in its linkage region the 4-O-sulfated Gal structure. cyclohexenoesculetin-beta-galactoside 90-93 amyloid beta (A4) precursor protein Mus musculus 34-41 11479316-10 2001 Thus, appican is the first example of a specific brain CSPG that contains the E disaccharide unit in its sugar backbone and the 4-O-sulfated Gal residue in its linkage region. cyclohexenoesculetin-beta-galactoside 141-144 amyloid beta (A4) precursor protein Mus musculus 6-13 11535116-6 2001 CG-16 has a preference for the beta-anomer of Gal at the non-reducing end of oligosaccharides with a Gal(beta1-4) linkage >Gal(beta1-3)> or =Gal(beta1-6). cyclohexenoesculetin-beta-galactoside 46-49 galectin 1B Gallus gallus 0-5 11535116-6 2001 CG-16 has a preference for the beta-anomer of Gal at the non-reducing end of oligosaccharides with a Gal(beta1-4) linkage >Gal(beta1-3)> or =Gal(beta1-6). cyclohexenoesculetin-beta-galactoside 46-49 basic helix-loop-helix family member e22 Gallus gallus 105-112 11535116-6 2001 CG-16 has a preference for the beta-anomer of Gal at the non-reducing end of oligosaccharides with a Gal(beta1-4) linkage >Gal(beta1-3)> or =Gal(beta1-6). cyclohexenoesculetin-beta-galactoside 46-49 basic helix-loop-helix family member e22 Gallus gallus 130-137 11535116-8 2001 The binding site of CG-16 is as large as a tetrasaccharide of the beta-anomer of Gal, and is most complementary to lacto-N-tetraose and Gal(beta1-4)GlcNAc related sequences. cyclohexenoesculetin-beta-galactoside 81-84 galectin 1B Gallus gallus 20-25 18429112-4 2001 These methods are followed by protocols for more comprehensive analysis of O-GlcNAc modified proteins, including labeling of O-GlcNAc residues with [3H]Gal, and subsequent product analysis. cyclohexenoesculetin-beta-galactoside 152-155 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 75-83 18429112-4 2001 These methods are followed by protocols for more comprehensive analysis of O-GlcNAc modified proteins, including labeling of O-GlcNAc residues with [3H]Gal, and subsequent product analysis. cyclohexenoesculetin-beta-galactoside 152-155 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 125-133 11535116-5 2001 It was 2.1x10(3) nM and 3.0 times more potent than Gal and Gal(beta1-4)GlcNAc (II)/Gal(beta1-3)GlcNAc(beta1-3)Gal(beta1-4)Glc (lacto-N-tetraose) respectively. cyclohexenoesculetin-beta-galactoside 59-62 basic helix-loop-helix family member e22 Gallus gallus 63-70 11535116-5 2001 It was 2.1x10(3) nM and 3.0 times more potent than Gal and Gal(beta1-4)GlcNAc (II)/Gal(beta1-3)GlcNAc(beta1-3)Gal(beta1-4)Glc (lacto-N-tetraose) respectively. cyclohexenoesculetin-beta-galactoside 59-62 basic helix-loop-helix family member e22 Gallus gallus 87-94 11535116-5 2001 It was 2.1x10(3) nM and 3.0 times more potent than Gal and Gal(beta1-4)GlcNAc (II)/Gal(beta1-3)GlcNAc(beta1-3)Gal(beta1-4)Glc (lacto-N-tetraose) respectively. cyclohexenoesculetin-beta-galactoside 59-62 basic helix-loop-helix family member e22 Gallus gallus 102-109 11535116-5 2001 It was 2.1x10(3) nM and 3.0 times more potent than Gal and Gal(beta1-4)GlcNAc (II)/Gal(beta1-3)GlcNAc(beta1-3)Gal(beta1-4)Glc (lacto-N-tetraose) respectively. cyclohexenoesculetin-beta-galactoside 59-62 basic helix-loop-helix family member e22 Gallus gallus 63-70 11535116-5 2001 It was 2.1x10(3) nM and 3.0 times more potent than Gal and Gal(beta1-4)GlcNAc (II)/Gal(beta1-3)GlcNAc(beta1-3)Gal(beta1-4)Glc (lacto-N-tetraose) respectively. cyclohexenoesculetin-beta-galactoside 59-62 basic helix-loop-helix family member e22 Gallus gallus 87-94 11535116-5 2001 It was 2.1x10(3) nM and 3.0 times more potent than Gal and Gal(beta1-4)GlcNAc (II)/Gal(beta1-3)GlcNAc(beta1-3)Gal(beta1-4)Glc (lacto-N-tetraose) respectively. cyclohexenoesculetin-beta-galactoside 59-62 basic helix-loop-helix family member e22 Gallus gallus 102-109 11502266-7 2001 Alpha-lactalbumin (alpha-LA) inhibited up to 85%, the transfer of Gal to the GlcNAc moiety linked either to Man or GlcNAc. cyclohexenoesculetin-beta-galactoside 66-69 lactalbumin alpha Homo sapiens 19-27 11326337-5 2001 Naturally occurring N-terminal PAH mutations are distributed in a nonrandom pattern and cluster within residues 46-48 (GAL) and 65-69 (IESRP), two motifs highly conserved in PDH. cyclohexenoesculetin-beta-galactoside 119-122 phenylalanine hydroxylase Homo sapiens 31-34 11384981-8 2001 The identity of the reaction products of Lc3 synthase-transfected CHOP2/1 cells was confirmed by thin-layer chromatography immunostaining using antibodies TE-8 and 1B2 that recognize Lc3 and Gal(beta1,4)GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide (nLc4) structures, respectively. cyclohexenoesculetin-beta-galactoside 191-194 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 Mus musculus 41-53 11384981-8 2001 The identity of the reaction products of Lc3 synthase-transfected CHOP2/1 cells was confirmed by thin-layer chromatography immunostaining using antibodies TE-8 and 1B2 that recognize Lc3 and Gal(beta1,4)GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide (nLc4) structures, respectively. cyclohexenoesculetin-beta-galactoside 191-194 microtubule-associated protein 1 light chain 3 alpha Mus musculus 41-44 11384981-8 2001 The identity of the reaction products of Lc3 synthase-transfected CHOP2/1 cells was confirmed by thin-layer chromatography immunostaining using antibodies TE-8 and 1B2 that recognize Lc3 and Gal(beta1,4)GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide (nLc4) structures, respectively. cyclohexenoesculetin-beta-galactoside 218-221 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 Mus musculus 41-53 11384981-8 2001 The identity of the reaction products of Lc3 synthase-transfected CHOP2/1 cells was confirmed by thin-layer chromatography immunostaining using antibodies TE-8 and 1B2 that recognize Lc3 and Gal(beta1,4)GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide (nLc4) structures, respectively. cyclohexenoesculetin-beta-galactoside 218-221 microtubule-associated protein 1 light chain 3 alpha Mus musculus 41-44 11384981-2 2001 The entry point for lacto-series glycolipids is catalyzed by the beta1,3 N-acetylglucosaminyltransferase GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide (Lc3) synthase enzyme. cyclohexenoesculetin-beta-galactoside 120-123 hemoglobin, beta adult major chain Mus musculus 65-72 11384981-2 2001 The entry point for lacto-series glycolipids is catalyzed by the beta1,3 N-acetylglucosaminyltransferase GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide (Lc3) synthase enzyme. cyclohexenoesculetin-beta-galactoside 120-123 hemoglobin, beta adult major chain Mus musculus 112-119 11384981-2 2001 The entry point for lacto-series glycolipids is catalyzed by the beta1,3 N-acetylglucosaminyltransferase GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide (Lc3) synthase enzyme. cyclohexenoesculetin-beta-galactoside 120-123 hemoglobin, beta adult major chain Mus musculus 124-131 11384981-2 2001 The entry point for lacto-series glycolipids is catalyzed by the beta1,3 N-acetylglucosaminyltransferase GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide (Lc3) synthase enzyme. cyclohexenoesculetin-beta-galactoside 120-123 microtubule-associated protein 1 light chain 3 alpha Mus musculus 146-149 11467948-6 2001 The heterogeneous N-linked oligosaccharides of TNFR-IgG contain sialic acid (Sia), Gal, and GlcNAc as terminal sugar residues. cyclohexenoesculetin-beta-galactoside 83-86 TNF receptor superfamily member 1A Homo sapiens 47-51 11467948-8 2001 Treatment of TNFR-IgG with beta1,4GT and UDP-Gal, in the presence of MnCl(2), followed by MALDI-TOF-MS analysis of PNGase F-released N-glycans showed that the number of oligosaccharides with terminal GlcNAc residues was significantly decreased with a concomitant increase in the number of terminal Gal residues. cyclohexenoesculetin-beta-galactoside 45-48 TNF receptor superfamily member 1A Homo sapiens 13-17 12064597-4 2001 Further analysis by sucrose gradient fractionation showed that Cx43 and Cx43/beta-gal were assembled into a sub-hexameric complex, and that Cx43/beta-gal expression also inhibited Cx43 assembly into hemichannels. cyclohexenoesculetin-beta-galactoside 82-85 gap junction protein, alpha 3 Mus musculus 72-76 11360267-5 2001 In addition, a significant negative relationship between glu-gal Hyl urinary level and duration of illness was found in ALS patients. cyclohexenoesculetin-beta-galactoside 61-64 megakaryocyte-associated tyrosine kinase Homo sapiens 65-68 12064597-4 2001 Further analysis by sucrose gradient fractionation showed that Cx43 and Cx43/beta-gal were assembled into a sub-hexameric complex, and that Cx43/beta-gal expression also inhibited Cx43 assembly into hemichannels. cyclohexenoesculetin-beta-galactoside 82-85 gap junction protein, alpha 3 Mus musculus 72-76 12064597-4 2001 Further analysis by sucrose gradient fractionation showed that Cx43 and Cx43/beta-gal were assembled into a sub-hexameric complex, and that Cx43/beta-gal expression also inhibited Cx43 assembly into hemichannels. cyclohexenoesculetin-beta-galactoside 82-85 gap junction protein, alpha 3 Mus musculus 72-76 11133864-4 2001 METHODS: IL-18 detection was performed by using 5-bromo-4-chloro-3-indoyl-ss--D-galactopyranoside (X-Gal) staining on frozen sections of eyes from mice (129/CD1, DBA1, and Balb/c), either of normal phenotype (+/+) or of deficiency (+/-, -/-) in the IL-18 gene which had been replaced by introduced genes including LacZ under the control of an IL-18 promotor. cyclohexenoesculetin-beta-galactoside 101-104 interleukin 18 Mus musculus 9-14 11008489-8 2001 Induction of GAL expression triggers Gal4p-dependent upstream nucleosome disruption. cyclohexenoesculetin-beta-galactoside 13-16 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 37-42 11511811-6 2000 Proton NMR analysis of product showed incorporation of GlcNAc in beta1,3 linkage to the terminal Gal of Gal(beta1-4)Glc(beta1-O-benzyl). cyclohexenoesculetin-beta-galactoside 97-100 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 Mus musculus 65-72 11511811-6 2000 Proton NMR analysis of product showed incorporation of GlcNAc in beta1,3 linkage to the terminal Gal of Gal(beta1-4)Glc(beta1-O-benzyl). cyclohexenoesculetin-beta-galactoside 104-108 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 Mus musculus 65-72 10929004-4 2000 The synthesis was accomplished by C-6 oxidation of Gal from TFD or its alpha-benzyl derivative (BzlalphaTFD), followed by reductive amination between the C-6 aldehyde yielded and the available amine of protein. cyclohexenoesculetin-beta-galactoside 51-54 complement component 6 Mus musculus 34-37 11002187-1 2000 The effect of alpha-NeuAc(2-->6)Gal/GalNAc-specific lectin from Sambucus nigra (SNA) on the release of lysozyme from human neutrophils was studied in vitro. cyclohexenoesculetin-beta-galactoside 35-38 lysozyme Homo sapiens 106-114 10777713-5 2000 The results obtained clearly showed a decrease of GalNAc, Gal, and sialic acid in IgAN compared with non-IgAN and normal controls, and those strongly suggested the possibility that the decreased galactosylation and sialylation of the IgA1 hinge result in its glomerular deposition in IgAN. cyclohexenoesculetin-beta-galactoside 50-53 IGAN1 Homo sapiens 82-86 10873579-3 2000 Src family kinase was translocated into and enriched in GEM fractions when prepared in 0.5 or 0.25% Triton X-100 from cells grown in Gal-containing medium, whereby GM3 synthesis is induced. cyclohexenoesculetin-beta-galactoside 133-136 proto-oncogene tyrosine-protein kinase Src Cricetulus griseus 0-3 10805731-3 2000 Gal4p S699 phosphorylation is necessary for sensitive response to inducer, and its requirement for GAL induction can be abrogated by high concentrations of galactose in strains expressing wild-type GAL2 and GAL3. cyclohexenoesculetin-beta-galactoside 99-102 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 0-5 10837462-1 2000 We have previously reported the molecular cloning of beta1, 3-galactosyltransferase-V (beta3GalT-V), which catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. cyclohexenoesculetin-beta-galactoside 92-95 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase) Mus musculus 189-194 10837462-1 2000 We have previously reported the molecular cloning of beta1, 3-galactosyltransferase-V (beta3GalT-V), which catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. cyclohexenoesculetin-beta-galactoside 92-95 hemoglobin, beta adult major chain Mus musculus 218-225 10939515-6 2000 Our results suggest the presence of N-acetylglucosamine (GlcNAc), Man, Glc, N-acetylneuraminic acid (Neu5Ac)(alpha2-6)- and Neu5Ac(alpha2-3)-linked, N-acetylgalactosamine (GalNAc) and Gal(beta1-3)GalNAc in the oligosaccharides of the goblet cells. cyclohexenoesculetin-beta-galactoside 172-175 immunoglobulin binding protein 1 Homo sapiens 109-117 10777713-5 2000 The results obtained clearly showed a decrease of GalNAc, Gal, and sialic acid in IgAN compared with non-IgAN and normal controls, and those strongly suggested the possibility that the decreased galactosylation and sialylation of the IgA1 hinge result in its glomerular deposition in IgAN. cyclohexenoesculetin-beta-galactoside 50-53 immunoglobulin heavy constant alpha 1 Homo sapiens 234-238 10815756-13 2000 In conclusion, the inhibitory effect of Gal(1-16) on exogenous and endogenous CCK-stimulated pancreatic secretion was found to be more potent in the presence of glucose both in anesthetized and in conscious rats. cyclohexenoesculetin-beta-galactoside 40-43 cholecystokinin Rattus norvegicus 78-81 10207016-6 1999 In addition, the pre-S2 domain of M protein, but not that of L protein, was found to be partially O-glycosylated by a Gal(beta1-3)GalNAcalpha-, Neu5Ac(alpha2-3)Gal(beta1-3)GalNAcalpha-, or GalNAcalpha-residue. cyclohexenoesculetin-beta-galactoside 118-121 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 122-129 10588748-2 1999 GAL(1-15) induced, in the presence of tetrodotoxin, a dose-dependent hyperpolarization in hippocampal CA3 neurons. cyclohexenoesculetin-beta-galactoside 0-3 carbonic anhydrase 3 Homo sapiens 102-105 10583371-8 1999 From the present observations, it can be concluded that the Wistaria agglutinin (WSA) binds to the C-3, C-4 and C-6 positions of GalNAc and Gal residues; the N-acetyl group at C-2 enhances its binding dramatically. cyclohexenoesculetin-beta-galactoside 129-132 complement C3 Homo sapiens 99-107 10427856-2 1999 Among these molecules, the selectins expressed on endothelial cells (E- and P-selectins) and leucocytes (L-selectin) recognize carbohydrate ligands such as sialyl Lewis A or sialyl Lewis X oligosaccharides due to the same positioning of NeuAc, Gal and Fuc residues in both isomeric structures. cyclohexenoesculetin-beta-galactoside 244-247 selectin L Homo sapiens 105-115 10215702-5 1999 Pharmacokinetic analysis revealed that the hepatic uptake clearances of 111In-Suc-CAT, 111In-Gal-CAT, and 111In-Man-CAT were much greater than that of 111In-CAT, whereas that of 111In-PEG-CAT was very small. cyclohexenoesculetin-beta-galactoside 92-96 catalase Homo sapiens 97-100 10215702-5 1999 Pharmacokinetic analysis revealed that the hepatic uptake clearances of 111In-Suc-CAT, 111In-Gal-CAT, and 111In-Man-CAT were much greater than that of 111In-CAT, whereas that of 111In-PEG-CAT was very small. cyclohexenoesculetin-beta-galactoside 92-96 catalase Homo sapiens 97-100 10504403-7 1999 The majority of nonsialylated N-acetyllactosamine antennae bear terminal alpha1-3-linked Gal residues. cyclohexenoesculetin-beta-galactoside 89-92 adrenoceptor alpha 1D Homo sapiens 73-81 10464766-4 1999 The glycoform, referred to as Peak 1, contains the O-linked glycan Neu5Ac(alpha 2-3)Gal(beta 1-3)GalNAc; the Peak 2 glycoform contains the O-linked glycan Neu5Ac(alpha 2-3)Gal(beta 1-3)[Neu5Ac(alpha 2-6)]GalNAc. cyclohexenoesculetin-beta-galactoside 83-87 pseudopodium-enriched atypical kinase 1 Mus musculus 30-36 10215702-5 1999 Pharmacokinetic analysis revealed that the hepatic uptake clearances of 111In-Suc-CAT, 111In-Gal-CAT, and 111In-Man-CAT were much greater than that of 111In-CAT, whereas that of 111In-PEG-CAT was very small. cyclohexenoesculetin-beta-galactoside 92-96 catalase Homo sapiens 97-100 10215702-5 1999 Pharmacokinetic analysis revealed that the hepatic uptake clearances of 111In-Suc-CAT, 111In-Gal-CAT, and 111In-Man-CAT were much greater than that of 111In-CAT, whereas that of 111In-PEG-CAT was very small. cyclohexenoesculetin-beta-galactoside 92-96 catalase Homo sapiens 97-100 9804157-7 1998 Then, beta-gal expression in each photocoagulation-induced CNVM was examined by observing the exposed fundus of the eyes stained with the beta-gal substrate X-Gal. cyclohexenoesculetin-beta-galactoside 159-162 galactosidase, beta 1 Rattus norvegicus 6-14 9887326-4 1999 X-Gal staining of Dp71-null mouse embryos and tissues revealed a very stage- and cell type-specific activity of the Dp71 promoter during development and during differentiation of various tissues, including the nervous system, eyes, limb buds, lungs, blood vessels, vibrissae and hair follicles. cyclohexenoesculetin-beta-galactoside 2-5 dystrophin, muscular dystrophy Mus musculus 18-22 9887326-4 1999 X-Gal staining of Dp71-null mouse embryos and tissues revealed a very stage- and cell type-specific activity of the Dp71 promoter during development and during differentiation of various tissues, including the nervous system, eyes, limb buds, lungs, blood vessels, vibrissae and hair follicles. cyclohexenoesculetin-beta-galactoside 2-5 dystrophin, muscular dystrophy Mus musculus 116-120 9986848-1 1999 We describe a new chromogenic agar medium, ABC medium (alphabeta-chromogenic medium), which includes two substrates, 3, 4-cyclohexenoesculetin-beta-D-galactoside and 5-bromo-4-chloro-3-indolyl-alpha-D-galactopyranoside, to facilitate the selective isolation of Salmonella spp. cyclohexenoesculetin-beta-galactoside 117-161 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 43-46 9765298-0 1998 The centrally acting beta1,6N-acetylglucosaminyltransferase (GlcNAc to gal). cyclohexenoesculetin-beta-galactoside 71-74 glucosaminyl (N-acetyl) transferase 1 Homo sapiens 21-59 9437906-15 1997 The Gal-PEG10-DAG liposomes were cleared from the plasma with a half life of 0.3 h. The plasma elimination could be attributed entirely to increased uptake by the liver. cyclohexenoesculetin-beta-galactoside 4-7 paternally expressed 10 Rattus norvegicus 8-13 10100886-1 1998 We have previously demonstrated that gonadotrophin-releasing hormone (GnRH) induces not only changes in quantity but also in quality on secreted luteinizing hormone (LH), by increasing [14C]Leu (translation) and [3H]Gal (distal glycosylation) incorporation into newly synthesized hormone. cyclohexenoesculetin-beta-galactoside 216-219 gonadotropin releasing hormone 1 Homo sapiens 37-68 10100886-1 1998 We have previously demonstrated that gonadotrophin-releasing hormone (GnRH) induces not only changes in quantity but also in quality on secreted luteinizing hormone (LH), by increasing [14C]Leu (translation) and [3H]Gal (distal glycosylation) incorporation into newly synthesized hormone. cyclohexenoesculetin-beta-galactoside 216-219 gonadotropin releasing hormone 1 Homo sapiens 70-74 9593693-11 1998 Amino acid sequence homology analysis revealed that this enzyme shared 39% homology with mouse beta-1, 4-galactosyltransferase (EC 2.4.1.38), which catalyzes the transfer of Gal to beta-1,4-GlcNAc in glycoproteins. cyclohexenoesculetin-beta-galactoside 174-177 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 Mus musculus 95-126 9787410-9 1998 The aggregation inhibition effect could partially be blocked by preincubation of PRP with soluble Gal alpha 1-3Gal, Gal alpha 1-3 beta 1-4GlcNAc, lactose, galactose, and glucose, but not by lactosamine, galactosamine, or glucosamine. cyclohexenoesculetin-beta-galactoside 98-101 complement component 4 binding protein alpha Homo sapiens 81-84 9648266-3 1997 The third one, nonasaccharide Neu5Ac(alpha 2-3)Gal(beta 1-4)GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)] GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)]GlcNAc, is a sialylated and internally difucosylated derivative of a trimeric N-acetyllactosamine. cyclohexenoesculetin-beta-galactoside 47-50 tubulin beta 3 class III Homo sapiens 51-59 9648266-3 1997 The third one, nonasaccharide Neu5Ac(alpha 2-3)Gal(beta 1-4)GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)] GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)]GlcNAc, is a sialylated and internally difucosylated derivative of a trimeric N-acetyllactosamine. cyclohexenoesculetin-beta-galactoside 47-50 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 67-75 9648266-3 1997 The third one, nonasaccharide Neu5Ac(alpha 2-3)Gal(beta 1-4)GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)] GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)]GlcNAc, is a sialylated and internally difucosylated derivative of a trimeric N-acetyllactosamine. cyclohexenoesculetin-beta-galactoside 47-50 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 80-88 9648266-3 1997 The third one, nonasaccharide Neu5Ac(alpha 2-3)Gal(beta 1-4)GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)] GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)]GlcNAc, is a sialylated and internally difucosylated derivative of a trimeric N-acetyllactosamine. cyclohexenoesculetin-beta-galactoside 47-50 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 113-121 9648266-3 1997 The third one, nonasaccharide Neu5Ac(alpha 2-3)Gal(beta 1-4)GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)] GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)]GlcNAc, is a sialylated and internally difucosylated derivative of a trimeric N-acetyllactosamine. cyclohexenoesculetin-beta-galactoside 47-50 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 80-88 9648266-3 1997 The third one, nonasaccharide Neu5Ac(alpha 2-3)Gal(beta 1-4)GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)] GlcNAc(beta 1-3)Gal(beta 1-4)[Fuc(alpha 1-3)]GlcNAc, is a sialylated and internally difucosylated derivative of a trimeric N-acetyllactosamine. cyclohexenoesculetin-beta-galactoside 47-50 adrenoceptor alpha 1D Homo sapiens 140-149 9660787-2 1998 SKP1 from Dictyostelium has been known to be modified by an oligosaccharide containing Fuc and Gal, which is unusual for a cytoplasmic or nuclear protein. cyclohexenoesculetin-beta-galactoside 95-98 S-phase kinase associated protein 1 Homo sapiens 0-4 9511986-2 1997 However, we recently found that the murine enzyme UDP-Gal:Gal beta1 -->4GLcNAc (Gal to Gal) alpha1,3 galactosyltransferase (alpha1,3GT) is secreted in a soluble form into media by mouse teratocarcinoma F9 cells (Cho SK, Yeh J-C, Cho M, Cummings RD (1996) J Biol Chem 271: 3238-46). cyclohexenoesculetin-beta-galactoside 54-57 adrenoceptor alpha 1D Homo sapiens 127-137 9374524-8 1997 Gal6p also appears to have a negative effect on the GAL system as a deletion of the gene leads to a 2-5-fold higher expression of the GAL1, GAL2, GAL7, and MEL1 genes. cyclohexenoesculetin-beta-galactoside 52-55 bleomycin hydrolase Saccharomyces cerevisiae S288C 0-5 9374524-8 1997 Gal6p also appears to have a negative effect on the GAL system as a deletion of the gene leads to a 2-5-fold higher expression of the GAL1, GAL2, GAL7, and MEL1 genes. cyclohexenoesculetin-beta-galactoside 52-55 galactokinase Saccharomyces cerevisiae S288C 134-138 9374524-8 1997 Gal6p also appears to have a negative effect on the GAL system as a deletion of the gene leads to a 2-5-fold higher expression of the GAL1, GAL2, GAL7, and MEL1 genes. cyclohexenoesculetin-beta-galactoside 52-55 galactose permease GAL2 Saccharomyces cerevisiae S288C 140-144 9374524-8 1997 Gal6p also appears to have a negative effect on the GAL system as a deletion of the gene leads to a 2-5-fold higher expression of the GAL1, GAL2, GAL7, and MEL1 genes. cyclohexenoesculetin-beta-galactoside 52-55 UDP-glucose:hexose-1-phosphate uridylyltransferase Saccharomyces cerevisiae S288C 146-150 9511986-2 1997 However, we recently found that the murine enzyme UDP-Gal:Gal beta1 -->4GLcNAc (Gal to Gal) alpha1,3 galactosyltransferase (alpha1,3GT) is secreted in a soluble form into media by mouse teratocarcinoma F9 cells (Cho SK, Yeh J-C, Cho M, Cummings RD (1996) J Biol Chem 271: 3238-46). cyclohexenoesculetin-beta-galactoside 58-61 adrenoceptor alpha 1D Homo sapiens 127-137 9041256-8 1997 The hepatoprotective effect is still observed when rIL-10 is injected 30 or 120 minutes after Gal/LPS. cyclohexenoesculetin-beta-galactoside 94-97 interleukin 10 Rattus norvegicus 51-57 9376678-6 1997 An examination of activity present in six human sera revealed a specificity of the serum enzyme toward beta1,3 linked Gal, particularly, the T-hapten without beta1,6 branching. cyclohexenoesculetin-beta-galactoside 118-121 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 103-110 9213396-2 1997 HIV-1 gp120 binding proteins of the CD4-negative and Gal-C-negative, non-productively infectable human glioblastoma cell line D54 were purified by affinity chromatography over a gp120-conjugated sepharose column and identified by peptide microsequencing. cyclohexenoesculetin-beta-galactoside 53-56 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 6-11 9050845-3 1997 Recent experiments have indicated that a direct interaction between Gal3p and Gal80p plays a pivotal role in an early step of GAL induction. cyclohexenoesculetin-beta-galactoside 126-129 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 68-73 9050845-3 1997 Recent experiments have indicated that a direct interaction between Gal3p and Gal80p plays a pivotal role in an early step of GAL induction. cyclohexenoesculetin-beta-galactoside 126-129 transcription regulator GAL80 Saccharomyces cerevisiae S288C 78-84 9214299-3 1997 Protons of the exocyclic hydroxymethyl group on the terminal Gal residue of globotriaosylceramide (Gb3) were replaced with deuterium. cyclohexenoesculetin-beta-galactoside 61-64 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 99-102 9147050-1 1997 We have previously shown that chondroitin 6-sulfotransferase (C6ST) catalyzes transfer of sulfate not only to position 6 of GalNAc residue of chondroitin but also to position 6 of Gal residue of keratan sulfate. cyclohexenoesculetin-beta-galactoside 124-127 carbohydrate sulfotransferase 3 Homo sapiens 30-60 9147050-1 1997 We have previously shown that chondroitin 6-sulfotransferase (C6ST) catalyzes transfer of sulfate not only to position 6 of GalNAc residue of chondroitin but also to position 6 of Gal residue of keratan sulfate. cyclohexenoesculetin-beta-galactoside 124-127 carbohydrate sulfotransferase 3 Homo sapiens 62-66 9147050-8 1997 These observations show that C6ST could transfer sulfate to position 6 of Gal residue of SLN. cyclohexenoesculetin-beta-galactoside 74-77 carbohydrate sulfotransferase 3 Homo sapiens 29-33 9147050-8 1997 These observations show that C6ST could transfer sulfate to position 6 of Gal residue of SLN. cyclohexenoesculetin-beta-galactoside 74-77 sarcolipin Homo sapiens 89-92 9041256-10 1997 CONCLUSIONS: These results indicate that IL-10 protects the liver in the Gal/LPS mouse model. cyclohexenoesculetin-beta-galactoside 73-76 interleukin 10 Mus musculus 41-46 9228276-10 1997 One substrate, Ub-Proline-beta gal, was found to require MCB1 for its breakdown, but it remains unclear whether Mcb1 serves as a ubiquitin receptor in this process. cyclohexenoesculetin-beta-galactoside 31-34 proteasome regulatory particle base subunit RPN10 Saccharomyces cerevisiae S288C 57-61 9061507-9 1996 GAL infusion clearly enhanced the PRL response to TRH (AUC: 5806.3 +/- 743.0 vs 3952.1 +/- 423.9 micrograms.min/L, p < 0.05) and ARG (AUC: 3676.8 +/- 382.6 vs 2638.9 +/- 287.0 micrograms.min/L, p < 0.05), respectively. cyclohexenoesculetin-beta-galactoside 0-3 thyrotropin releasing hormone Homo sapiens 50-53 9033386-5 1997 Lys211 of the K3 mutant, which corresponds to Lys111 of E-selectin, interacts with each of the three bound ligands: the N zeta atom donates a hydrogen bond to the 4-OH of Gal in 3"-NeuAc-Le(x), forms a water-mediated hydrogen bond with the 4-OH of Gal in 3"-sulfo-Le(x), and forms a salt bridge with the sulfate group of 4"-sulfo-Le(x). cyclohexenoesculetin-beta-galactoside 171-174 selectin E Homo sapiens 56-66 9033386-5 1997 Lys211 of the K3 mutant, which corresponds to Lys111 of E-selectin, interacts with each of the three bound ligands: the N zeta atom donates a hydrogen bond to the 4-OH of Gal in 3"-NeuAc-Le(x), forms a water-mediated hydrogen bond with the 4-OH of Gal in 3"-sulfo-Le(x), and forms a salt bridge with the sulfate group of 4"-sulfo-Le(x). cyclohexenoesculetin-beta-galactoside 248-251 selectin E Homo sapiens 56-66 9111137-7 1997 Furthermore, those oligosaccharides which lack only one terminal Gal are exclusively galactosylated on the GlcNAc(beta1,2) Man(alpha1,6) Man(beta1,4) antenna. cyclohexenoesculetin-beta-galactoside 65-68 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 141-148 9111137-7 1997 Furthermore, those oligosaccharides which lack only one terminal Gal are exclusively galactosylated on the GlcNAc(beta1,2) Man(alpha1,6) Man(beta1,4) antenna. cyclohexenoesculetin-beta-galactoside 65-68 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 114-121 9111137-7 1997 Furthermore, those oligosaccharides which lack only one terminal Gal are exclusively galactosylated on the GlcNAc(beta1,2) Man(alpha1,6) Man(beta1,4) antenna. cyclohexenoesculetin-beta-galactoside 65-68 adrenoceptor alpha 1D Homo sapiens 127-135 9061507-12 1996 During GAL infusion, the PRL response to TRH or ARG remained lower (p < 0.01) than that after MCP administration. cyclohexenoesculetin-beta-galactoside 7-10 thyrotropin releasing hormone Homo sapiens 41-44 7844177-11 1994 CHO cells transfected with DNA encoding HM-Gal were exposed to mevalonic acid, which enhances the rate of HMG CoA reductase degradation several fold, and leads to the reduction of the steady state levels of HM-Gal by 80-90%. cyclohexenoesculetin-beta-galactoside 42-46 3-hydroxy-3-methylglutaryl-coenzyme A reductase Cricetulus griseus 106-123 7594218-6 1995 GAL enhanced the GHRH-induced GH rise (2129.5 +/- 362.2 micrograms/l/h, p < 0.05) but SAL pretreatment inhibited this effect (1249.8 +/- 257.1 micrograms/l/h, p < 0.02) so that the GH response to the combined administration of GHRH, GAL and SAL overlapped with that to the neurohormone alone. cyclohexenoesculetin-beta-galactoside 0-3 growth hormone releasing hormone Homo sapiens 17-21 8885835-2 1996 Under the conditions comprising 2.0 x 10(-3) M labeling reagent and 1.0 x 10(-5) M human lysozyme at pH 5.4, 37 degrees C, the reaction time required to reduce the lytic activity against Micrococcus luteus cells to 50% of its initial activity was lengthened by 3.7 times through the substitution of the nonreducing end sugar residue, GlcNAc to Gal. cyclohexenoesculetin-beta-galactoside 344-347 lysozyme Homo sapiens 89-97 8688427-12 1996 (k) C-6 sulfation of Gal on the T-hapten did not affect the acceptor activity. cyclohexenoesculetin-beta-galactoside 21-24 complement C6 Homo sapiens 4-7 8688427-13 1996 (l) C-6 sulfation of GalNAc decreased the activity to 70%, whereas on C-6 sulfation of both Gal and GalNAc the T-hapten lost the acceptor ability. cyclohexenoesculetin-beta-galactoside 21-24 complement C6 Homo sapiens 4-7 8688427-16 1996 (o) The enhancement of enzyme affinity by a sulfo group on C-6 of Gal was demonstrated by an increase (approximately 5-fold) in the K(m) for Gal beta 1,4GlcNAc beta 1,6(Gal beta 1,3)GalNAc alpha-O-Bn in presence of 6-sulfoGal beta 1,- 4GlcNAc beta-O-Me (3.0 mM). cyclohexenoesculetin-beta-galactoside 66-69 complement C6 Homo sapiens 59-62 8694771-6 1996 This (beta 1-3)GalT specifically transfers Gal residues from UDP-Gal to exogenously added L. donovani LPG acceptor. cyclohexenoesculetin-beta-galactoside 15-18 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 6-14 8694771-10 1996 This suggests that more than one (beta 1-3)GalT is involved in the addition of these Gal units and that the solubilized activity is the (beta 1-3)GalT that adds the first beta Gal residue to the acceptor. cyclohexenoesculetin-beta-galactoside 43-46 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 34-42 8694771-10 1996 This suggests that more than one (beta 1-3)GalT is involved in the addition of these Gal units and that the solubilized activity is the (beta 1-3)GalT that adds the first beta Gal residue to the acceptor. cyclohexenoesculetin-beta-galactoside 85-88 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 34-42 8785493-4 1996 The presence of GalNAc in addition to GlcNAc, Fuc, Gal, and Man, in sugar chains of rK1 was confirmed by high pH anion exchange chromatography following acid hydrolysis. cyclohexenoesculetin-beta-galactoside 16-19 keratin 1 Rattus norvegicus 84-87 7494242-1 1995 The primary receptor for human immunodeficiency virus (HIV) is the CD4 molecule; however, in vitro evidence suggests that a neutral glycolipid, galactosyl ceramide (GalCer) or a derivative molecule, 3" sulfogalactosyl ceramide (GalS), may serve as an alternative receptor for HIV type 1 (HIV-1) in cells of neural and colonic origin. cyclohexenoesculetin-beta-galactoside 228-232 CD4 molecule Homo sapiens 67-70 7559635-6 1995 In vitro, the murine alpha 1-3FT can efficiently fucosylate the trisaccharide Gal alpha 1-3Gal beta 1-4GlcNAc (apparent Km of 0.71 mM) to form an unusual tetrasaccharide (Gal alpha 1-3Gal beta 1-4[Fuc alpha 1-3]GlcNAc) described in periimplantation mouse tissues. cyclohexenoesculetin-beta-galactoside 78-81 fucosyltransferase 4 Mus musculus 21-32 7594218-6 1995 GAL enhanced the GHRH-induced GH rise (2129.5 +/- 362.2 micrograms/l/h, p < 0.05) but SAL pretreatment inhibited this effect (1249.8 +/- 257.1 micrograms/l/h, p < 0.02) so that the GH response to the combined administration of GHRH, GAL and SAL overlapped with that to the neurohormone alone. cyclohexenoesculetin-beta-galactoside 239-242 growth hormone releasing hormone Homo sapiens 17-21 7795413-5 1995 In contrast, sialyl or sulfate group on C-6 and sulfate on C-3 of Gal in Gal beta 1,3GalNAc alpha- inhibited almost completely the interaction of PNA with ACGM but had only a slight effect on the interaction of ABA; C-6 substitution with either sialic acid or sulfate on GalNAc alpha- almost abolished the interaction of both HPA and VVA with ACGM. cyclohexenoesculetin-beta-galactoside 66-69 complement C6 Homo sapiens 40-43 7795413-5 1995 In contrast, sialyl or sulfate group on C-6 and sulfate on C-3 of Gal in Gal beta 1,3GalNAc alpha- inhibited almost completely the interaction of PNA with ACGM but had only a slight effect on the interaction of ABA; C-6 substitution with either sialic acid or sulfate on GalNAc alpha- almost abolished the interaction of both HPA and VVA with ACGM. cyclohexenoesculetin-beta-galactoside 66-69 complement C6 Homo sapiens 216-219 7944531-6 1994 The serum disialotransferrin, studied in the present patient, contained two moles of truncated monoantennary Sialyl-Gal-GlcNAc-Man(alpha 1-->3)[Man(alpha 1-->6)]Man(beta 1-->4)GlcNAc (beta 1-->4)GlcNAc-Asn per mole of transferrin. cyclohexenoesculetin-beta-galactoside 116-119 transferrin Homo sapiens 17-28 8031418-2 1994 The tetrameric lectin from Glycine max (soybean) (SBA) has been shown to cross-link and precipitate with N-linked multiantennary complex type oligosaccharides containing nonreducing terminal Gal residues (Bhattacharyya, L., Haraldsson, M., & Brewer, C. F. (1988) Biochemistry 27, 1034-1041). cyclohexenoesculetin-beta-galactoside 191-194 LOW QUALITY PROTEIN: lectin Glycine max 15-21 8056347-4 1994 Gal-Tf could also be produced extracellularly using a fusion of the pre-pro region of the yeast Mf alpha 1 precursor (MF alpha 1) to soluble Gal-Tf; a fusion containing only the pre-region of Mf alpha 1 was synthesized intracellularly, but did not lead to Gal-Tf activity in the culture medium. cyclohexenoesculetin-beta-galactoside 0-3 Mf(Alpha)1p Saccharomyces cerevisiae S288C 96-128 8056347-4 1994 Gal-Tf could also be produced extracellularly using a fusion of the pre-pro region of the yeast Mf alpha 1 precursor (MF alpha 1) to soluble Gal-Tf; a fusion containing only the pre-region of Mf alpha 1 was synthesized intracellularly, but did not lead to Gal-Tf activity in the culture medium. cyclohexenoesculetin-beta-galactoside 0-3 Mf(Alpha)1p Saccharomyces cerevisiae S288C 96-106 1836212-10 1991 Proton NMR analyses of the three products demonstrated that GlcNAc was added in a beta 1-6 linkage to the penultimate GalNAc or Gal, suggesting that this enzyme is capable of synthesizing all beta 6GlcNAc structures found in mucin-type oligosaccharides. cyclohexenoesculetin-beta-galactoside 118-121 mucin 1, cell surface associated Bos taurus 225-230 7512967-6 1994 It was revealed that approximately 40% of the heavy chain of the mouse IgG2b are O-glycosylated at Thr-221A in the hinge region, predominantly with a tetrasaccharide composed of GalNAc, Gal, and two N-glycolylneuraminic acid residues. cyclohexenoesculetin-beta-galactoside 178-181 immunoglobulin heavy constant gamma 2B Mus musculus 71-76 8021969-1 1994 We examined the binding of the gp120 envelope glycoprotein (gp120) of the human immunodeficiency virus (HIV-1) to sulfatide (GalS), galactocerebroside (GalC), and GM1-ganglioside (GM1). cyclohexenoesculetin-beta-galactoside 125-129 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 31-36 8021969-1 1994 We examined the binding of the gp120 envelope glycoprotein (gp120) of the human immunodeficiency virus (HIV-1) to sulfatide (GalS), galactocerebroside (GalC), and GM1-ganglioside (GM1). cyclohexenoesculetin-beta-galactoside 125-129 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 60-65 8021969-2 1994 The gp120 glycoprotein bound to GalS but not to GalC or GM1 by enzyme-linked immunosorbent assay (ELISA) and by an immunospot assay on nitrocellulose paper. cyclohexenoesculetin-beta-galactoside 32-36 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 4-9 8021969-4 1994 In studies to determine whether GalS could be a receptor for gp120 on the surface of cells, gp120 bound to GalS incorporated into the plasma membrane of lymphoid cells as determined by cytofluorometric analysis and immunofluorescence microscopy. cyclohexenoesculetin-beta-galactoside 32-36 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 61-66 8021969-4 1994 In studies to determine whether GalS could be a receptor for gp120 on the surface of cells, gp120 bound to GalS incorporated into the plasma membrane of lymphoid cells as determined by cytofluorometric analysis and immunofluorescence microscopy. cyclohexenoesculetin-beta-galactoside 32-36 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 92-97 8021969-4 1994 In studies to determine whether GalS could be a receptor for gp120 on the surface of cells, gp120 bound to GalS incorporated into the plasma membrane of lymphoid cells as determined by cytofluorometric analysis and immunofluorescence microscopy. cyclohexenoesculetin-beta-galactoside 107-111 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 61-66 8021969-4 1994 In studies to determine whether GalS could be a receptor for gp120 on the surface of cells, gp120 bound to GalS incorporated into the plasma membrane of lymphoid cells as determined by cytofluorometric analysis and immunofluorescence microscopy. cyclohexenoesculetin-beta-galactoside 107-111 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 92-97 8021969-5 1994 These studies indicate that GalS may function as a receptor for gp120 and HIV-1. cyclohexenoesculetin-beta-galactoside 28-32 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 64-69 8252697-3 1993 METHODS AND RESULTS: We used a recombinant adenovirus, Ad.RSV beta gal, which contained the beta-galactosidase (beta-gal) histochemical marker gene. cyclohexenoesculetin-beta-galactoside 67-70 galactosidase, beta 1 Rattus norvegicus 92-110 8252697-3 1993 METHODS AND RESULTS: We used a recombinant adenovirus, Ad.RSV beta gal, which contained the beta-galactosidase (beta-gal) histochemical marker gene. cyclohexenoesculetin-beta-galactoside 67-70 galactosidase, beta 1 Rattus norvegicus 92-100 8314763-1 1993 Apparent kinetic parameters have been measured for the transfer of N-acetyl-D-neuraminic acid (Neu5Ac) from CMP-Neu5Ac to analogues of the Gal(beta 1-4)GlcNAc (type II) and Gal(beta 1-3)GlcNAc (type I) substrates by the rat liver Gal(beta 1-4)GlcNAc alpha 2,6-sialyltransferase and the Gal(beta 1-3/4)GlcNAc alpha 2,3-sialyltransferase. cyclohexenoesculetin-beta-galactoside 139-142 galanin and GMAP prepropeptide Rattus norvegicus 230-277 8314763-1 1993 Apparent kinetic parameters have been measured for the transfer of N-acetyl-D-neuraminic acid (Neu5Ac) from CMP-Neu5Ac to analogues of the Gal(beta 1-4)GlcNAc (type II) and Gal(beta 1-3)GlcNAc (type I) substrates by the rat liver Gal(beta 1-4)GlcNAc alpha 2,6-sialyltransferase and the Gal(beta 1-3/4)GlcNAc alpha 2,3-sialyltransferase. cyclohexenoesculetin-beta-galactoside 139-142 galanin and GMAP prepropeptide Rattus norvegicus 286-335 8471074-8 1993 On the other hand, after absorption of p-nitrophenyl beta-D-galactopyranoside (p-NP beta gal), which is actively absorbed by glucose transport carrier, p-NP beta gal itself appeared mostly on the serosal side. cyclohexenoesculetin-beta-galactoside 60-63 purine nucleoside phosphorylase Rattus norvegicus 79-83 8471074-8 1993 On the other hand, after absorption of p-nitrophenyl beta-D-galactopyranoside (p-NP beta gal), which is actively absorbed by glucose transport carrier, p-NP beta gal itself appeared mostly on the serosal side. cyclohexenoesculetin-beta-galactoside 60-63 purine nucleoside phosphorylase Rattus norvegicus 152-156 1282933-2 1992 The gp120 protein bound to sulfatide (GalS), a sulfated glycolipid autoantigen implicated in sensory neuritis, and to the myelin associated glycoprotein (MAG), an autoantigen in demyelinating neuropathy. cyclohexenoesculetin-beta-galactoside 38-42 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 4-9 1334673-5 1992 A single strand nick was introduced at the centre of a symmetrized gal site and this reduces the binding energy of CRP by about 0.6 Kcal. cyclohexenoesculetin-beta-galactoside 67-70 catabolite gene activator protein Escherichia coli 115-118 1378950-6 1992 However, human GAL showed similar biological activity to the other (amidated) GALs here. cyclohexenoesculetin-beta-galactoside 78-82 galanin and GMAP prepropeptide Homo sapiens 15-18 1581037-0 1992 Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc. cyclohexenoesculetin-beta-galactoside 78-81 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 69-77 1581037-0 1992 Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc. cyclohexenoesculetin-beta-galactoside 78-81 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 69-75 1581037-0 1992 Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc. cyclohexenoesculetin-beta-galactoside 78-81 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 82-88 1581037-0 1992 Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc. cyclohexenoesculetin-beta-galactoside 78-81 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 82-88 1581037-0 1992 Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc. cyclohexenoesculetin-beta-galactoside 78-81 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 82-88 1581037-0 1992 Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc. cyclohexenoesculetin-beta-galactoside 78-81 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 165-173 1581037-0 1992 Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc. cyclohexenoesculetin-beta-galactoside 78-81 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 82-88 1581037-0 1992 Enzymatic in vitro synthesis of radiolabeled pentasaccharides GlcNAc beta 1-3(Gal beta 1-4GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc and the isomeric Gal beta 1-4GlcNAc beta 1-3(GlcNAc beta 1-6)Gal beta 1-4GlcNAc/Glc. cyclohexenoesculetin-beta-galactoside 78-81 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 82-88 8180186-2 1994 The tetrameric lectin from Glycine max (soybean) (SBA) has been shown to cross-link and precipitate with N-linked multiantennary complex type oligosaccharides containing nonreducing terminal Gal residues (Bhattacharyya, L., Haraldsson, M., & Brewer, C. F. (1988) Biochemistry 27, 1034-1041). cyclohexenoesculetin-beta-galactoside 191-194 LOW QUALITY PROTEIN: lectin Glycine max 15-21 8126375-3 1994 Serous cells contained glycoconjugates with terminal Neu5Ac (alpha 2-3) Gal (beta 1-4) GlcNAc, Neu5Ac (alpha 2-6) Gal/GalNAc, Neu5Ac (alpha 2-3/6) Gal (beta 1-3 GalNAc, GlcNAc, and Gal (beta 1-4) GlcNAc sequences. cyclohexenoesculetin-beta-galactoside 72-75 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 77-83 8360147-10 1993 The phosphoglycan attached to the core consists of -PO4-6)Gal(beta 1-4)Man(alpha 1- repeats units which are either unsubstituted (70%) or substituted (30%) at the 3-position of the Gal residues with oligosaccharide side chains containing primarily Gal and some Glc. cyclohexenoesculetin-beta-galactoside 58-61 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 62-70 8360147-11 1993 Thirteen different types of side chains were identified with the structures [Gal(beta 1-3)]x, where x = 1-11, or Glc(1-3)Glc(1-3), or Glc(1-3)Gal(beta 1-3), where glucose is probably in the beta-configuration. cyclohexenoesculetin-beta-galactoside 77-80 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 81-87 8340428-5 1993 This enzyme also cleaved the N,N"-diacetylchitobiose moiety of the sugar chain of human transferrin tetraglycopeptide Asn-Tyr-Asn(GlcNAc)2(Man)3(GlcNAc)2(Gal)2-Lys to yield equimolar amounts of peptide Asn-Tyr-Asn(GlcNAc)Lys and sugar chain (Gal)2(GlcNAc)2(Man)3(GlcNAc). cyclohexenoesculetin-beta-galactoside 154-157 transferrin Homo sapiens 88-99 1448098-10 1992 Although an egd1 null mutant was viable and Gal+, induction of the galactose-regulated genes in the egd1 mutant strain was significantly reduced when cells were shifted from glucose to galactose. cyclohexenoesculetin-beta-galactoside 44-48 Egd1p Saccharomyces cerevisiae S288C 12-16 1425696-7 1992 500-MHz one-dimensional and two-dimensional 1H-NMR spectroscopy revealed their structures to be Sia alpha(2-3)Gal beta(1-4) [HSO3-6]GlcNAc beta(1-3)Gal and HSO3-6GlcNAc beta(1-3)Gal, showing that the sulfate-containing acidic chains are constructed with non-branched N-acetyllactosamine repeats which have sialic acid(s) at the non-reducing end(s) and sulfate at the C-6 position of GlcNAc residues. cyclohexenoesculetin-beta-galactoside 110-113 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 139-147 1425696-7 1992 500-MHz one-dimensional and two-dimensional 1H-NMR spectroscopy revealed their structures to be Sia alpha(2-3)Gal beta(1-4) [HSO3-6]GlcNAc beta(1-3)Gal and HSO3-6GlcNAc beta(1-3)Gal, showing that the sulfate-containing acidic chains are constructed with non-branched N-acetyllactosamine repeats which have sialic acid(s) at the non-reducing end(s) and sulfate at the C-6 position of GlcNAc residues. cyclohexenoesculetin-beta-galactoside 110-113 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 169-177 1425696-7 1992 500-MHz one-dimensional and two-dimensional 1H-NMR spectroscopy revealed their structures to be Sia alpha(2-3)Gal beta(1-4) [HSO3-6]GlcNAc beta(1-3)Gal and HSO3-6GlcNAc beta(1-3)Gal, showing that the sulfate-containing acidic chains are constructed with non-branched N-acetyllactosamine repeats which have sialic acid(s) at the non-reducing end(s) and sulfate at the C-6 position of GlcNAc residues. cyclohexenoesculetin-beta-galactoside 148-151 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 139-147 1400309-1 1992 The enzymatic transfer of Gal in beta 1,3 linkage to the GalNAc moiety of the core structure R1-GlcNAc beta 1,6GalNAc alpha-O-R2. cyclohexenoesculetin-beta-galactoside 26-29 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 33-41 1400309-1 1992 The enzymatic transfer of Gal in beta 1,3 linkage to the GalNAc moiety of the core structure R1-GlcNAc beta 1,6GalNAc alpha-O-R2. cyclohexenoesculetin-beta-galactoside 26-29 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 33-39 1457969-6 1992 The Man alpha 1-6 branch displayed structural heterogeneity in the terminal sequence, with chiefly alpha 2-3-sialylated Gal and/or 4-O-sulphated GalNAc. cyclohexenoesculetin-beta-galactoside 120-123 adrenoceptor alpha 1D Homo sapiens 8-17 1556114-10 1992 The third monosulfated compound has a novel O-sulfate on C-6 of the Gal residue attached to xylitol. cyclohexenoesculetin-beta-galactoside 68-71 complement C6 Homo sapiens 57-60 1370357-6 1992 Phosphorylated oligosaccharides P3, PO4-6[Gal(beta 1-3)[Gal(beta 1-4) Man(alpha 1-, and P4b, PO4-6[Gal(beta 1-3)Gal(beta 1-3)] Gal(beta 1-4)Man(alpha 1-, were also recognized by WIC 79.3 but with considerably lower (approximately 100-fold) affinities. cyclohexenoesculetin-beta-galactoside 42-45 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 46-54 1924399-2 1991 Groups that acted as a fluorescence donor (naphthyl-2-acetyl, Nap) or acceptor (dansylethylenediamine, Dan) were selectively attached to the N terminus of the peptide and a Gal residue [either 6" (shown below), 6, or 8] of the oligosaccharide, respectively. cyclohexenoesculetin-beta-galactoside 173-176 catenin beta like 1 Homo sapiens 62-65 1924399-2 1991 Groups that acted as a fluorescence donor (naphthyl-2-acetyl, Nap) or acceptor (dansylethylenediamine, Dan) were selectively attached to the N terminus of the peptide and a Gal residue [either 6" (shown below), 6, or 8] of the oligosaccharide, respectively. cyclohexenoesculetin-beta-galactoside 173-176 NBL1, DAN family BMP antagonist Homo sapiens 103-106 1850740-6 1991 The carbohydrate analysis of rhCG showing the presence of 2.1, 3.3, 7.38, 4.2, and 27.8 residues of Fuc, GalNAC, GlcNAC, Gal, and Man, respectively, per mole of the hormone was consistent with the presence of 4 N-linked high mannose type carbohydrate hydrate and 4 O-linked simple carbohydrate chains, probably made up of Gal-GalNAC. cyclohexenoesculetin-beta-galactoside 105-108 Rh family C glycoprotein Homo sapiens 29-33 1804533-2 1991 PG-1 contained the sequence----4)GalA- (1----2)-Rha-(1----4)-GalA-(1----, and partial acid hydrolysis gave GalA-(1----4)-Rha, GlcA-(1----4)-Rha, and several di- and oligosaccharides consisting variously of Xyl, Glc, Gal, and Man. cyclohexenoesculetin-beta-galactoside 33-36 galactosidase alpha Homo sapiens 61-65 1804533-2 1991 PG-1 contained the sequence----4)GalA- (1----2)-Rha-(1----4)-GalA-(1----, and partial acid hydrolysis gave GalA-(1----4)-Rha, GlcA-(1----4)-Rha, and several di- and oligosaccharides consisting variously of Xyl, Glc, Gal, and Man. cyclohexenoesculetin-beta-galactoside 33-36 galactosidase alpha Homo sapiens 61-65 2174368-9 1990 Thus, the results reveal that predominantly, the complex type N-glycans of the retroviral envelope glycoprotein display cell-specific variations including differences in oligosaccharide branching, sialylation and substitution by additional Gal(alpha 1-3) residues. cyclohexenoesculetin-beta-galactoside 240-243 melanoma antigen Mus musculus 90-111 1997323-12 1991 However, the alpha-1,3-Man-linked antenna in rTf-1 as well as rTf-2 had the sequence: Neu5Ac(alpha 2-3)Gal(beta 1-3)[Neu5Ac(alpha 2-6)]GlcNAc(beta 1-2)Man. cyclohexenoesculetin-beta-galactoside 103-106 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) Rattus norvegicus 45-50 1997323-12 1991 However, the alpha-1,3-Man-linked antenna in rTf-1 as well as rTf-2 had the sequence: Neu5Ac(alpha 2-3)Gal(beta 1-3)[Neu5Ac(alpha 2-6)]GlcNAc(beta 1-2)Man. cyclohexenoesculetin-beta-galactoside 103-106 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 107-113 1997323-12 1991 However, the alpha-1,3-Man-linked antenna in rTf-1 as well as rTf-2 had the sequence: Neu5Ac(alpha 2-3)Gal(beta 1-3)[Neu5Ac(alpha 2-6)]GlcNAc(beta 1-2)Man. cyclohexenoesculetin-beta-galactoside 103-106 immunoglobulin binding protein 1 Homo sapiens 124-133 1997323-12 1991 However, the alpha-1,3-Man-linked antenna in rTf-1 as well as rTf-2 had the sequence: Neu5Ac(alpha 2-3)Gal(beta 1-3)[Neu5Ac(alpha 2-6)]GlcNAc(beta 1-2)Man. cyclohexenoesculetin-beta-galactoside 103-106 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 142-150 1997323-13 1991 In addition, the alpha-1,6-Man-linked antenna deviated in rTf-2 from the standard structure by having the sequence: Neu5Ac(alpha 2-3)Gal(beta 1-3)GlcNAc(beta 1-2)Man. cyclohexenoesculetin-beta-galactoside 133-136 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 137-143 2019285-10 1991 Since oil granulomata are known to secrete interleukin 6, which has B cell-regulatory properties and is secreted by rheumatoid synovial cells, we tested sera from interleukin 6-transgenic mice, and found a strikingly raised percentage of Gal(O). cyclohexenoesculetin-beta-galactoside 238-241 interleukin 6 Mus musculus 43-56 1699938-2 1990 Pulse-chase experiments with [35S]methionine demonstrated that the reduced amounts of CO I and ND 5 subunits in Gal-32 are not the result of more rapid protein degradation. cyclohexenoesculetin-beta-galactoside 112-115 NADH dehydrogenase subunit 5 Cricetulus griseus 95-99 2201583-1 1990 Rat and human colonic mucin glycoproteins bind to the Gal/GalNAc adherence lectin on the surface of Entamoeba histolytica in vitro, thus inhibiting the organism from adhering to and lysing the target cells. cyclohexenoesculetin-beta-galactoside 54-57 LOC100508689 Homo sapiens 22-27 2159880-2 1990 Spatial structures of the oligosaccharide parts of globotriaosylceramide, Gal(alpha 1-4)Gal(beta 1-4)Glc(beta 1-1)Cer (Cer = ceramide) and isoglobotriaosylceramide, Gal(alpha 1-3)Gal(beta 1-4)Glc(beta 1-1)Cer were investigated in (C2H3)2SO solution by means of laboratory and rotating frame NOE, hydroxyl protons being used as long-range sensors defining the distance constraints. cyclohexenoesculetin-beta-galactoside 74-77 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 105-111 1696497-10 1990 The data indicate that OH groups at C-4 and C-6 of Gal and the OH at C-3 of GlcNAc in Gal beta(1,4)GlcNAc are important for lectin sugar interaction. cyclohexenoesculetin-beta-galactoside 51-54 complement C4A (Rodgers blood group) Homo sapiens 36-39 1696497-10 1990 The data indicate that OH groups at C-4 and C-6 of Gal and the OH at C-3 of GlcNAc in Gal beta(1,4)GlcNAc are important for lectin sugar interaction. cyclohexenoesculetin-beta-galactoside 51-54 complement C6 Homo sapiens 44-47 34846842-3 2021 In this strategy, the O-GlcNAc glycopeptides were first enzymatically labeled with a Gal moiety, followed by chemical oxidation to efficiently introduce the aldehyde groups. cyclohexenoesculetin-beta-galactoside 85-88 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 22-30 1689771-1 1990 An IgM monoclonal autoantibody (M-protein) with anti-Gal(beta 1-3)GalNAc activity from a patient with lower motor neuron disease bound to the surface of motoneurons isolated from bovine spinal cord. cyclohexenoesculetin-beta-galactoside 53-56 IgM Bos taurus 3-6 1689771-1 1990 An IgM monoclonal autoantibody (M-protein) with anti-Gal(beta 1-3)GalNAc activity from a patient with lower motor neuron disease bound to the surface of motoneurons isolated from bovine spinal cord. cyclohexenoesculetin-beta-galactoside 53-56 myomesin 2 Homo sapiens 32-41 1689771-1 1990 An IgM monoclonal autoantibody (M-protein) with anti-Gal(beta 1-3)GalNAc activity from a patient with lower motor neuron disease bound to the surface of motoneurons isolated from bovine spinal cord. cyclohexenoesculetin-beta-galactoside 53-56 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 57-65 15546874-3 2005 In this study, we found that galectin-4 binds to glycosphingolipids carrying 3-O-sulfated Gal residues, such as SB1a, SM3, SM4s, SB2, SM2a, and GM1, but not to glycosphingolipids with 3-O-sialylated Gal, such as sLc4Cer, snLc4Cer, GM3, GM2, and GM4, using both an enzyme-linked immunosorbent assay and a surface plasmon resonance assay. cyclohexenoesculetin-beta-galactoside 90-93 galectin 4 Homo sapiens 29-39 15546874-3 2005 In this study, we found that galectin-4 binds to glycosphingolipids carrying 3-O-sulfated Gal residues, such as SB1a, SM3, SM4s, SB2, SM2a, and GM1, but not to glycosphingolipids with 3-O-sialylated Gal, such as sLc4Cer, snLc4Cer, GM3, GM2, and GM4, using both an enzyme-linked immunosorbent assay and a surface plasmon resonance assay. cyclohexenoesculetin-beta-galactoside 199-202 galectin 4 Homo sapiens 29-39 34647616-6 2022 Interestingly, knocking out alpha-1,6-fucosyltransferase (FUT8KO), which removed core fucose, lowered the content of N-glycans with terminal Gal and increased levels of terminal GlcNAc and Man5 groups on WT antibody. cyclohexenoesculetin-beta-galactoside 141-144 fucosyltransferase 8 Homo sapiens 28-56 34647616-6 2022 Interestingly, knocking out alpha-1,6-fucosyltransferase (FUT8KO), which removed core fucose, lowered the content of N-glycans with terminal Gal and increased levels of terminal GlcNAc and Man5 groups on WT antibody. cyclohexenoesculetin-beta-galactoside 141-144 fucosyltransferase 8 Homo sapiens 58-64 34849833-0 2021 TORC1 signaling modulates Cdk8-dependent GAL gene expression in Saccharomyces cerevisiae. cyclohexenoesculetin-beta-galactoside 41-44 cyclin-dependent serine/threonine protein kinase SSN3 Saccharomyces cerevisiae S288C 26-30 34849833-8 2021 These observations demonstrate that TORC1 signaling regulates GAL induction through the activity of PP2A/Cdc55 and suggest that Cdk8-dependent phosphorylation of Gal4 is opposed by PP2A/Cdc55 dephosphorylation. cyclohexenoesculetin-beta-galactoside 62-65 protein phosphatase 2A regulatory subunit CDC55 Saccharomyces cerevisiae S288C 105-110 34849833-8 2021 These observations demonstrate that TORC1 signaling regulates GAL induction through the activity of PP2A/Cdc55 and suggest that Cdk8-dependent phosphorylation of Gal4 is opposed by PP2A/Cdc55 dephosphorylation. cyclohexenoesculetin-beta-galactoside 62-65 cyclin-dependent serine/threonine protein kinase SSN3 Saccharomyces cerevisiae S288C 128-132 34849833-8 2021 These observations demonstrate that TORC1 signaling regulates GAL induction through the activity of PP2A/Cdc55 and suggest that Cdk8-dependent phosphorylation of Gal4 is opposed by PP2A/Cdc55 dephosphorylation. cyclohexenoesculetin-beta-galactoside 62-65 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 162-166 34849833-8 2021 These observations demonstrate that TORC1 signaling regulates GAL induction through the activity of PP2A/Cdc55 and suggest that Cdk8-dependent phosphorylation of Gal4 is opposed by PP2A/Cdc55 dephosphorylation. cyclohexenoesculetin-beta-galactoside 62-65 protein phosphatase 2A regulatory subunit CDC55 Saccharomyces cerevisiae S288C 186-191 34575073-0 2021 Entamoeba histolytica Trophozoites Interact with the c-Met Receptor at the Surface of Liver Origin Cells through the Gal/GalNAc Amoebic Lectin. cyclohexenoesculetin-beta-galactoside 117-120 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 53-58 34805272-4 2021 Because of this reciprocal distribution of the alpha-gal epitope and anti-Gal in mammals, transplantation of organs from non-primate mammals (e.g., pig xenografts) into Old-World monkeys or humans results in hyperacute rejection following anti-Gal binding to alpha-gal epitopes on xenograft cells. cyclohexenoesculetin-beta-galactoside 244-247 GLA Sus scrofa 259-268 34805272-14 2021 Increasing anti-Gal-mediated protection against zoonotic viruses presenting alpha-gal epitopes and against protozoa, such as Trypanosoma, Leishmania, and Plasmodium, by vaccination for elevating production of the anti-Gal antibody. cyclohexenoesculetin-beta-galactoside 16-19 GLA Sus scrofa 76-85 34639188-5 2021 Moreover, we analysed by immunohistochemistry the expression of the immediate-early gene c-Fos (c-Fos IR) after the administration of GAL(1-15)+ESC in OBX rats in several nuclei involved in MDD. cyclohexenoesculetin-beta-galactoside 134-137 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 89-94 34639188-5 2021 Moreover, we analysed by immunohistochemistry the expression of the immediate-early gene c-Fos (c-Fos IR) after the administration of GAL(1-15)+ESC in OBX rats in several nuclei involved in MDD. cyclohexenoesculetin-beta-galactoside 134-137 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 96-101 34639188-6 2021 GAL(1-15) enhances the antidepressant-like effects of ESC, and the GALR2 antagonist M871 blocked GAL(1-15) mediated actions. cyclohexenoesculetin-beta-galactoside 97-100 galanin receptor 2 Rattus norvegicus 67-72 34575073-6 2021 In the present study, we searched for evidence of interaction between the Gal/GalNAc lectin at the surface of trophozoites with the c-Met receptor expressed at the surface of HepG2 in coculture assays. cyclohexenoesculetin-beta-galactoside 74-77 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 132-137 34575073-10 2021 Our results point to Gal/GalNAc lectin as a ligand of the c-Met receptor at the surface of HepG2 cells. cyclohexenoesculetin-beta-galactoside 21-24 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 58-63 34555499-6 2021 Characterization of the PSGL-1/mIg G2b O-glycans showed that Gal3ST2 preferentially sulfated Gal on the C-6 branch of core 2 structures and Gal3ST4 preferred Gal on the C-3 branch independently if core-1 or-2. cyclohexenoesculetin-beta-galactoside 93-96 selectin P ligand Homo sapiens 24-30 34462883-7 2022 Of them, both mRNA and protein expression levels of the beta-galactoside alpha2,6-sialyltransferase 1 (ST6Gal-I) had dramatically reduced in Cav-1-/- mice organ tissues, which was consistent with the alpha2,6-sialyl Gal/GalNAc level reduced significantly in tissues instead of serum from Cav-1-/- mice. cyclohexenoesculetin-beta-galactoside 216-219 beta galactoside alpha 2,6 sialyltransferase 1 Mus musculus 56-101 34462883-7 2022 Of them, both mRNA and protein expression levels of the beta-galactoside alpha2,6-sialyltransferase 1 (ST6Gal-I) had dramatically reduced in Cav-1-/- mice organ tissues, which was consistent with the alpha2,6-sialyl Gal/GalNAc level reduced significantly in tissues instead of serum from Cav-1-/- mice. cyclohexenoesculetin-beta-galactoside 216-219 beta galactoside alpha 2,6 sialyltransferase 1 Mus musculus 103-111 34462883-7 2022 Of them, both mRNA and protein expression levels of the beta-galactoside alpha2,6-sialyltransferase 1 (ST6Gal-I) had dramatically reduced in Cav-1-/- mice organ tissues, which was consistent with the alpha2,6-sialyl Gal/GalNAc level reduced significantly in tissues instead of serum from Cav-1-/- mice. cyclohexenoesculetin-beta-galactoside 216-219 caveolin 1, caveolae protein Mus musculus 141-146 34462883-7 2022 Of them, both mRNA and protein expression levels of the beta-galactoside alpha2,6-sialyltransferase 1 (ST6Gal-I) had dramatically reduced in Cav-1-/- mice organ tissues, which was consistent with the alpha2,6-sialyl Gal/GalNAc level reduced significantly in tissues instead of serum from Cav-1-/- mice. cyclohexenoesculetin-beta-galactoside 216-219 twinfilin actin binding protein 1 Mus musculus 200-208 34089718-2 2021 The toxin"s B subunit (RTB) is a Gal/GalNAc-specific lectin that attaches to cell surfaces and promotes retrograde transport of ricin"s A subunit (RTA) to the trans Golgi network (TGN) and endoplasmic reticulum (ER). cyclohexenoesculetin-beta-galactoside 33-36 MAS related GPR family member F Homo sapiens 147-150 34555499-6 2021 Characterization of the PSGL-1/mIg G2b O-glycans showed that Gal3ST2 preferentially sulfated Gal on the C-6 branch of core 2 structures and Gal3ST4 preferred Gal on the C-3 branch independently if core-1 or-2. cyclohexenoesculetin-beta-galactoside 93-96 immunoglobulin heavy constant gamma 2B Mus musculus 31-38 34555499-6 2021 Characterization of the PSGL-1/mIg G2b O-glycans showed that Gal3ST2 preferentially sulfated Gal on the C-6 branch of core 2 structures and Gal3ST4 preferred Gal on the C-3 branch independently if core-1 or-2. cyclohexenoesculetin-beta-galactoside 93-96 galactose-3-O-sulfotransferase 2 Homo sapiens 61-68 34555499-6 2021 Characterization of the PSGL-1/mIg G2b O-glycans showed that Gal3ST2 preferentially sulfated Gal on the C-6 branch of core 2 structures and Gal3ST4 preferred Gal on the C-3 branch independently if core-1 or-2. cyclohexenoesculetin-beta-galactoside 158-161 selectin P ligand Homo sapiens 24-30 34555499-6 2021 Characterization of the PSGL-1/mIg G2b O-glycans showed that Gal3ST2 preferentially sulfated Gal on the C-6 branch of core 2 structures and Gal3ST4 preferred Gal on the C-3 branch independently if core-1 or-2. cyclohexenoesculetin-beta-galactoside 158-161 galactose-3-O-sulfotransferase 4 Homo sapiens 140-147 34555499-7 2021 CHST1 sulfated Gal residues on both the C-3 (core 1/2) and C-6 branches of core 2 structures. cyclohexenoesculetin-beta-galactoside 15-18 carbohydrate sulfotransferase 1 Homo sapiens 0-5 35628602-7 2022 The Abeta oligomer detoxifying potential of GAL-201 has been demonstrated by means of single cell recordings in isolated hippocampal neurons (perforated patch experiments) as well as in vitro and in vivo extracellular monitoring of long-term potentiation (LTP, in rat transverse hippocampal slices), a cellular correlate for synaptic plasticity. cyclohexenoesculetin-beta-galactoside 44-47 amyloid beta precursor protein Rattus norvegicus 4-9 35355477-4 2022 In this study, we applied transcription activator-like effector nuclease (TALEN) to knock out the porcine alpha-1, 3-galactosyltransferase gene GGTA1, which encodes Gal epitopes that induce hyperacute immune rejection in pig-to-human xenotransplantation. cyclohexenoesculetin-beta-galactoside 165-168 N-acetyllactosaminide alpha-1,3-galactosyltransferase Sus scrofa 106-138 35355477-4 2022 In this study, we applied transcription activator-like effector nuclease (TALEN) to knock out the porcine alpha-1, 3-galactosyltransferase gene GGTA1, which encodes Gal epitopes that induce hyperacute immune rejection in pig-to-human xenotransplantation. cyclohexenoesculetin-beta-galactoside 165-168 N-acetyllactosaminide alpha-1,3-galactosyltransferase Sus scrofa 144-149 35087020-8 2022 In addition, the proper tuning of the immune secretory phenotype (IL1betalow, IL6low, IL10high) associated with a significant reduction in SA-beta Gal-positive area of aorta from AAV-LAV treated mice. cyclohexenoesculetin-beta-galactoside 147-150 interleukin 10 Mus musculus 86-90 34998886-4 2022 The branches, substituted at the O-2 of Gal and O-3 of Glc, contained (1 6)-2-OMe-alpha-D-Galp, (1 4)-beta-D-Glcp, (1 3)-beta-D-Glcp, and terminated by T-alpha-L-Fucp and T-beta-D-Glcp. cyclohexenoesculetin-beta-galactoside 40-43 galanin-like peptide Mus musculus 90-94 2668417-5 1989 Antibodies from such sera crosslink, via their antigen binding sites, the beta-Gal fusions to the corresponding CAT or DHFR fusions adsorbed to a solid phase as demonstrated by the captured beta-Gal activity. cyclohexenoesculetin-beta-galactoside 78-82 dihydrofolate reductase Mus musculus 119-123 2674159-10 1989 Ten days after the medium change, the amount of CEA released reaches a maximum value of 130 ng/10(6) cells/24 hr, which remains stable for differentiated HT29-D4 cells cultured in glucose-free, galactose-containing medium (Gal-medium) for several months. cyclohexenoesculetin-beta-galactoside 223-226 CEA cell adhesion molecule 3 Homo sapiens 48-51 2467679-1 1988 A partial purified polymerase from S. anatum was used for the synthesis of polysaccharide [-6) [14C]Man(beta 1-4)Rha(alpha 1-3)Gal(alpha 1-]n and its analogues containing D-glucose residue instead of D-galactose or D-mannose. cyclohexenoesculetin-beta-galactoside 127-130 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 104-112 2737211-3 1989 In the present report, twenty three oligosaccharide alditols are described and all possess a type two core consisting of the branched trisaccharide: Gal(beta 1-3)[GlcNAc(beta 1-6)]GalNAc-ol. cyclohexenoesculetin-beta-galactoside 149-152 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 153-161 2737211-3 1989 In the present report, twenty three oligosaccharide alditols are described and all possess a type two core consisting of the branched trisaccharide: Gal(beta 1-3)[GlcNAc(beta 1-6)]GalNAc-ol. cyclohexenoesculetin-beta-galactoside 149-152 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 170-178 2467679-1 1988 A partial purified polymerase from S. anatum was used for the synthesis of polysaccharide [-6) [14C]Man(beta 1-4)Rha(alpha 1-3)Gal(alpha 1-]n and its analogues containing D-glucose residue instead of D-galactose or D-mannose. cyclohexenoesculetin-beta-galactoside 127-130 adrenoceptor alpha 1D Homo sapiens 117-126 2467679-1 1988 A partial purified polymerase from S. anatum was used for the synthesis of polysaccharide [-6) [14C]Man(beta 1-4)Rha(alpha 1-3)Gal(alpha 1-]n and its analogues containing D-glucose residue instead of D-galactose or D-mannose. cyclohexenoesculetin-beta-galactoside 127-130 adrenoceptor alpha 1D Homo sapiens 117-124 4091823-7 1985 carry the same pentasaccharide GalNAc(beta 1-4)[NeuAc(alpha 2-3)]Gal(beta 1-3)[NeuAc(alpha 2-6)]GalNAc -ol(Cad determinant) but in different amounts. cyclohexenoesculetin-beta-galactoside 31-34 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 38-46 2457603-5 1988 Low levels of antibodies to Gal(beta 1-3)GlcNAc-BSA and to Gal(beta 1-3)GlcNAc-BSA were also detected in patients with amyotrophic lateral sclerosis (ALS) and in normal subjects at serum dilutions of up to 1:500, but these did not have the same specificity as the M-proteins, as binding to Gal(beta 1-3)GalNAc-BSA was not inhibited by absorption with Gal(beta 1-3)GlcNAc-BSA. cyclohexenoesculetin-beta-galactoside 28-31 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 32-40 2457603-5 1988 Low levels of antibodies to Gal(beta 1-3)GlcNAc-BSA and to Gal(beta 1-3)GlcNAc-BSA were also detected in patients with amyotrophic lateral sclerosis (ALS) and in normal subjects at serum dilutions of up to 1:500, but these did not have the same specificity as the M-proteins, as binding to Gal(beta 1-3)GalNAc-BSA was not inhibited by absorption with Gal(beta 1-3)GlcNAc-BSA. cyclohexenoesculetin-beta-galactoside 59-62 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 63-71 2457603-5 1988 Low levels of antibodies to Gal(beta 1-3)GlcNAc-BSA and to Gal(beta 1-3)GlcNAc-BSA were also detected in patients with amyotrophic lateral sclerosis (ALS) and in normal subjects at serum dilutions of up to 1:500, but these did not have the same specificity as the M-proteins, as binding to Gal(beta 1-3)GalNAc-BSA was not inhibited by absorption with Gal(beta 1-3)GlcNAc-BSA. cyclohexenoesculetin-beta-galactoside 59-62 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 63-71 2457603-5 1988 Low levels of antibodies to Gal(beta 1-3)GlcNAc-BSA and to Gal(beta 1-3)GlcNAc-BSA were also detected in patients with amyotrophic lateral sclerosis (ALS) and in normal subjects at serum dilutions of up to 1:500, but these did not have the same specificity as the M-proteins, as binding to Gal(beta 1-3)GalNAc-BSA was not inhibited by absorption with Gal(beta 1-3)GlcNAc-BSA. cyclohexenoesculetin-beta-galactoside 59-62 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 63-71 3733704-2 1986 The three lectins, RL-14.5, RL-18, and RL-29, had a similar apparent affinity for lactose and associated with the same critical determinants, which included positions 4 and 6 of Gal and part of Glc. cyclohexenoesculetin-beta-galactoside 178-181 ribosomal protein L14 Homo sapiens 19-24 3733704-6 1986 For RL-29 activity was markedly enhanced by GalNAc alpha 1-3 substitution on Gal, a modification which had little effect with RL-18 and inhibited binding to RL-14.5. cyclohexenoesculetin-beta-galactoside 44-47 ribosomal protein L14 Homo sapiens 157-162 2449247-4 1988 The monoclonal antibody was found to be highly specific to GM2(NeuGc) and the epitope was a non-reducing terminal GalNAc beta 1-4[NeuGc alpha 2-3]Gal structure. cyclohexenoesculetin-beta-galactoside 114-117 cytochrome b5 domain containing 2 Mus musculus 59-69 3304661-3 1987 Under conditions where the gal element would normally be either activating or nonactivating, his3 transcription by T7 RNA polymerase was not stimulated above the level observed in the absence of any upstream element. cyclohexenoesculetin-beta-galactoside 27-30 imidazoleglycerol-phosphate dehydratase HIS3 Saccharomyces cerevisiae S288C 93-97 2426270-9 1986 All fibronectins examined were strongly reactive with monoclonal antibody AH8-28, which binds to Gal beta 1----3GalNAc residues, and this reactivity was localized to both the NH2-terminal half and COOH-terminal half of the S-cyanylation-cleaved fibronectin molecule. cyclohexenoesculetin-beta-galactoside 97-100 fibronectin 1 Homo sapiens 4-15 4091823-7 1985 carry the same pentasaccharide GalNAc(beta 1-4)[NeuAc(alpha 2-3)]Gal(beta 1-3)[NeuAc(alpha 2-6)]GalNAc -ol(Cad determinant) but in different amounts. cyclohexenoesculetin-beta-galactoside 31-34 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 69-77 3003212-3 1985 PNA is highly specific for the terminal carbohydrate linkage Gal beta-(1----3)-Gal NAc which is only exposed to hCG when the O-serine linked oligosaccharide of its unique beta-CTP region is deficient in sialic acid. cyclohexenoesculetin-beta-galactoside 61-64 synuclein alpha Homo sapiens 83-86 3003212-3 1985 PNA is highly specific for the terminal carbohydrate linkage Gal beta-(1----3)-Gal NAc which is only exposed to hCG when the O-serine linked oligosaccharide of its unique beta-CTP region is deficient in sialic acid. cyclohexenoesculetin-beta-galactoside 61-64 chorionic gonadotropin subunit beta 5 Homo sapiens 112-115 3976840-3 1985 Purified podocalyxin from both control and PAN rats was found to contain sialic acid, Gal, GlcNac, and Man but lacked Fuc and GalNac by gas-liquid chromatography. cyclohexenoesculetin-beta-galactoside 86-89 podocalyxin-like Rattus norvegicus 9-20 3934006-3 1985 PNA is highly specific for the terminal carbohydrate linkage Gal beta-(1----3)-GalNAc which is only exposed in hCG when the O-serine linked oligosaccharide of its unique beta-CTP region are desialylated. cyclohexenoesculetin-beta-galactoside 61-64 chorionic gonadotropin subunit beta 5 Homo sapiens 111-114 3922430-6 1985 The glycopeptides which bound to Datura-lectin were degraded by endo-beta-galactosidase (or keratanase) to yield Gal----GlcNAc----Gal and glycopeptides, which were resistant to further endo-beta-galactosidase digestion and which no longer bound to Datura lectin-agarose. cyclohexenoesculetin-beta-galactoside 113-116 galactosidase, beta 1 Mus musculus 69-87 3922430-6 1985 The glycopeptides which bound to Datura-lectin were degraded by endo-beta-galactosidase (or keratanase) to yield Gal----GlcNAc----Gal and glycopeptides, which were resistant to further endo-beta-galactosidase digestion and which no longer bound to Datura lectin-agarose. cyclohexenoesculetin-beta-galactoside 113-116 galactosidase, beta 1 Mus musculus 190-208 6198241-3 1983 When galactokinase-deficient (gall-) yeasts were transformed with these plasmids the resulting Gal+ transformants were heterogeneous with respect to their galactokinase levels. cyclohexenoesculetin-beta-galactoside 95-99 galactokinase Saccharomyces cerevisiae S288C 5-18 3918040-10 1985 The O-linked oligosaccharides from both MAT-B1 and MAT-C1 ASGP-1 have been shown to contain a core tetrasaccharide Gal(beta 1-4)GlcNAc(beta 1-6)(Gal(beta 1-3]GalNAc in which both galactose residues may be linked to additional sugars (Hull, S. R., Laine, R. A., Kaizu, T., Rodriquez, I., and Carraway, K. L. (1984) J. Biol. cyclohexenoesculetin-beta-galactoside 115-118 mucin 4, cell surface associated Rattus norvegicus 58-64 6437450-9 1984 170, 343-349): NeuAc(alpha 2-6)Gal(beta 1-4)GlcNAc(beta 1-2)Man(alpha 1-3)[Gal(beta 1-4)Glc-NAc(beta 1-2)Man(alpha 1-6)]Man(beta 1-4)]Glc-NAc(beta 1-4) [Fuc(alpha 1-6)]GlcNAc. cyclohexenoesculetin-beta-galactoside 31-34 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 35-41 6437450-9 1984 170, 343-349): NeuAc(alpha 2-6)Gal(beta 1-4)GlcNAc(beta 1-2)Man(alpha 1-3)[Gal(beta 1-4)Glc-NAc(beta 1-2)Man(alpha 1-6)]Man(beta 1-4)]Glc-NAc(beta 1-4) [Fuc(alpha 1-6)]GlcNAc. cyclohexenoesculetin-beta-galactoside 31-34 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 51-59 6437450-9 1984 170, 343-349): NeuAc(alpha 2-6)Gal(beta 1-4)GlcNAc(beta 1-2)Man(alpha 1-3)[Gal(beta 1-4)Glc-NAc(beta 1-2)Man(alpha 1-6)]Man(beta 1-4)]Glc-NAc(beta 1-4) [Fuc(alpha 1-6)]GlcNAc. cyclohexenoesculetin-beta-galactoside 31-34 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 51-57 6437450-9 1984 170, 343-349): NeuAc(alpha 2-6)Gal(beta 1-4)GlcNAc(beta 1-2)Man(alpha 1-3)[Gal(beta 1-4)Glc-NAc(beta 1-2)Man(alpha 1-6)]Man(beta 1-4)]Glc-NAc(beta 1-4) [Fuc(alpha 1-6)]GlcNAc. cyclohexenoesculetin-beta-galactoside 31-34 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 51-57 6437450-9 1984 170, 343-349): NeuAc(alpha 2-6)Gal(beta 1-4)GlcNAc(beta 1-2)Man(alpha 1-3)[Gal(beta 1-4)Glc-NAc(beta 1-2)Man(alpha 1-6)]Man(beta 1-4)]Glc-NAc(beta 1-4) [Fuc(alpha 1-6)]GlcNAc. cyclohexenoesculetin-beta-galactoside 31-34 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 51-57 6704415-3 1984 Digestion of these 3H-labeled glycopeptides with endo-beta-galactosidase resulted in the release of smaller size saccharides, which were characterized as having the structure sialic acid----Gal----GlcNAc----Gal. cyclohexenoesculetin-beta-galactoside 190-193 galactosidase beta 1 Homo sapiens 54-72 6226539-0 1983 Sera of i subjects have the capacity to synthesize the branched GlcNAc beta (1 leads to 6)[GlcNAc(beta 1 leads to 3)]Gal ... structure. cyclohexenoesculetin-beta-galactoside 117-120 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 98-104 6584083-2 1983 Chemically, the antigen was identified as ganglioside GD2 [Gal NAc beta 1----4 (Neu Ac alpha 2----8 Neu Ac alpha 2---3) Gal beta 1----4 Glc----ceramide]. cyclohexenoesculetin-beta-galactoside 59-62 neuralized E3 ubiquitin protein ligase 1 Homo sapiens 80-83 6352703-1 1983 A hybrid molecule was constructed by covalently linking, by a disulfide bridge, the hormone insulin to the binding subunit B of the plant toxin ricin (specificity: Gal, GalNAc). cyclohexenoesculetin-beta-galactoside 164-167 insulin Canis lupus familiaris 92-99 6619126-8 1983 Gal(beta 1,3/4)GlcNAc(beta 1,6)]H2GalNAc and NeuAc(alpha 2,3) Gal(beta 1,3)[Gal(beta 1,3/4)GlcNAc(beta 1,6)]H2GalNAc were the predominant species present. cyclohexenoesculetin-beta-galactoside 0-3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 4-10 6619126-8 1983 Gal(beta 1,3/4)GlcNAc(beta 1,6)]H2GalNAc and NeuAc(alpha 2,3) Gal(beta 1,3)[Gal(beta 1,3/4)GlcNAc(beta 1,6)]H2GalNAc were the predominant species present. cyclohexenoesculetin-beta-galactoside 0-3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 22-28 6619126-10 1983 )[Gal(beta 1,3/4)Glc-NAc(beta 1,?)] cyclohexenoesculetin-beta-galactoside 2-5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 6-12 6619126-10 1983 )[Gal(beta 1,3/4)Glc-NAc(beta 1,?)] cyclohexenoesculetin-beta-galactoside 2-5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 25-31 6786888-14 1981 The second O-glycosidically-linked chain was a disialylated tetrasaccharide with the structure, Neu(alpha 2 leads to 3)Gal(beta 1 leads to 3)[NeuAc(alpha 2 leads to 6)GalNAc leads to Ser. cyclohexenoesculetin-beta-galactoside 119-122 neuralized E3 ubiquitin protein ligase 1 Homo sapiens 96-99 11894929-2 1983 We show that, although CRP binding to the gal fragment is weaker than binding to the lac fragment, in each case, stable complexes are formed between one dimer of CRP and one molecule of DNA. cyclohexenoesculetin-beta-galactoside 42-45 catabolite gene activator protein Escherichia coli 23-26 11894929-2 1983 We show that, although CRP binding to the gal fragment is weaker than binding to the lac fragment, in each case, stable complexes are formed between one dimer of CRP and one molecule of DNA. cyclohexenoesculetin-beta-galactoside 42-45 catabolite gene activator protein Escherichia coli 162-165 6809899-4 1982 The neutral glycosphingolipids consisted of glucosylceramide (GlcCer), lactosylceramide (LacCer), GalNAc (beta 1 leads to 4) Gal(beta 1 leads to 4)Glc(beta 1 leads to 1)Cer (GgOse3Cer), and GalNAc(beta 1 leads to 3)Gal(alpha 1 leads to 4) Gal(beta 1 leads to 4)Glc(beta 1 leads to 1)Cer (GbOse4Cer) according to their HPLC behavior. cyclohexenoesculetin-beta-galactoside 98-101 galanin and GMAP prepropeptide Mus musculus 106-157 272643-3 1978 The second fucosyltransferase catalyzes the transfer of fucose to lactotriaosylceramide [GlcNAc(beta1-3)Gal(beta1-4)Glc-Cer] to form a tetraglycosylceramide intermediate of the novel Lea-type glycolipid. cyclohexenoesculetin-beta-galactoside 104-107 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 96-103 39937-3 1979 The following components were identified: Gal(beta 1 leads to 4) [Fuc(alpha 1 leads to 3)]GlcNAc(beta 1 leads to 3)Manol,GlcNAc(beta 1 leads to 3)Manol, and Manol. cyclohexenoesculetin-beta-galactoside 42-45 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 46-52 39937-3 1979 The following components were identified: Gal(beta 1 leads to 4) [Fuc(alpha 1 leads to 3)]GlcNAc(beta 1 leads to 3)Manol,GlcNAc(beta 1 leads to 3)Manol, and Manol. cyclohexenoesculetin-beta-galactoside 42-45 adrenoceptor alpha 1D Homo sapiens 70-77 39937-3 1979 The following components were identified: Gal(beta 1 leads to 4) [Fuc(alpha 1 leads to 3)]GlcNAc(beta 1 leads to 3)Manol,GlcNAc(beta 1 leads to 3)Manol, and Manol. cyclohexenoesculetin-beta-galactoside 42-45 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 97-103 39937-3 1979 The following components were identified: Gal(beta 1 leads to 4) [Fuc(alpha 1 leads to 3)]GlcNAc(beta 1 leads to 3)Manol,GlcNAc(beta 1 leads to 3)Manol, and Manol. cyclohexenoesculetin-beta-galactoside 42-45 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 97-103 272643-3 1978 The second fucosyltransferase catalyzes the transfer of fucose to lactotriaosylceramide [GlcNAc(beta1-3)Gal(beta1-4)Glc-Cer] to form a tetraglycosylceramide intermediate of the novel Lea-type glycolipid. cyclohexenoesculetin-beta-galactoside 104-107 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 108-115 6449508-9 1980 Preliminary evidence has been obtained indicating that sialic acid linked alpha 2-6 to GalNAc or L-fucose linked alpha 1-2 to Gal inhibit the action of the beta 6-N-acetylglucosaminyltransferase on Gal beta 1-3GalNAc-porcine submaxillary mucin polypeptide. cyclohexenoesculetin-beta-galactoside 87-90 mucin Canis lupus familiaris 238-243 857425-1 1977 A human antibody which preferentially agglutinates p erythrocytes is inhibited specifically by the glycolipid sialosylparagloboside, NeuNAc (alpha,2 leads to 3)Gal(beta,1 leads t0 4)GlcNAc(beta,1 leads to 3)Gal(beta,1 leads to 4)Glc-Cer and forms a precipitin band with this compound in agarose gel. cyclohexenoesculetin-beta-galactoside 160-163 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 164-170 857425-1 1977 A human antibody which preferentially agglutinates p erythrocytes is inhibited specifically by the glycolipid sialosylparagloboside, NeuNAc (alpha,2 leads to 3)Gal(beta,1 leads t0 4)GlcNAc(beta,1 leads to 3)Gal(beta,1 leads to 4)Glc-Cer and forms a precipitin band with this compound in agarose gel. cyclohexenoesculetin-beta-galactoside 160-163 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 189-195 857425-1 1977 A human antibody which preferentially agglutinates p erythrocytes is inhibited specifically by the glycolipid sialosylparagloboside, NeuNAc (alpha,2 leads to 3)Gal(beta,1 leads t0 4)GlcNAc(beta,1 leads to 3)Gal(beta,1 leads to 4)Glc-Cer and forms a precipitin band with this compound in agarose gel. cyclohexenoesculetin-beta-galactoside 160-163 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 189-195 857425-1 1977 A human antibody which preferentially agglutinates p erythrocytes is inhibited specifically by the glycolipid sialosylparagloboside, NeuNAc (alpha,2 leads to 3)Gal(beta,1 leads t0 4)GlcNAc(beta,1 leads to 3)Gal(beta,1 leads to 4)Glc-Cer and forms a precipitin band with this compound in agarose gel. cyclohexenoesculetin-beta-galactoside 207-210 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 164-170 857425-1 1977 A human antibody which preferentially agglutinates p erythrocytes is inhibited specifically by the glycolipid sialosylparagloboside, NeuNAc (alpha,2 leads to 3)Gal(beta,1 leads t0 4)GlcNAc(beta,1 leads to 3)Gal(beta,1 leads to 4)Glc-Cer and forms a precipitin band with this compound in agarose gel. cyclohexenoesculetin-beta-galactoside 207-210 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 189-195 857425-1 1977 A human antibody which preferentially agglutinates p erythrocytes is inhibited specifically by the glycolipid sialosylparagloboside, NeuNAc (alpha,2 leads to 3)Gal(beta,1 leads t0 4)GlcNAc(beta,1 leads to 3)Gal(beta,1 leads to 4)Glc-Cer and forms a precipitin band with this compound in agarose gel. cyclohexenoesculetin-beta-galactoside 207-210 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 189-195 33901620-11 2021 However, this effect not only increased the desirable beta 1-4 Gal linkage to GlcNAc but unfortunately in NS0 cells increased the formation of Galalpha1-3 Gal which was shown to increase x3 in the presence of combinations of the MGU supplements. cyclohexenoesculetin-beta-galactoside 63-66 brain protein 1 Mus musculus 54-62 33445163-4 2021 On the other hand, Gal can specifically bind to the asialoglycoprotein receptor (ASGPR) which is highly expressed on membrane of hepatoma cells. cyclohexenoesculetin-beta-galactoside 19-22 asialoglycoprotein receptor 1 Homo sapiens 52-79 33445163-4 2021 On the other hand, Gal can specifically bind to the asialoglycoprotein receptor (ASGPR) which is highly expressed on membrane of hepatoma cells. cyclohexenoesculetin-beta-galactoside 19-22 asialoglycoprotein receptor 1 Homo sapiens 81-86 33854948-3 2021 A novel fusion enzyme, labeled mTfR-GLB1, was designed to act as a ferry across the BBB by fusing beta-gal to the mouse monoclonal antibody against the mouse transferrin receptor and tested in a murine model of GM1-gangliosidosis (beta-gal-/-). cyclohexenoesculetin-beta-galactoside 102-106 transferrin receptor Mus musculus 31-35 33314719-15 2021 The expression of P21 and P53 significantly decreased in SNPC-exo-treated NPC after siRNA transfection (P < 0.05), followed by a higher growth rate (2 times higher on the 5th day and 1.5 times higher on the 7th day) and lower percentage of SA-beta-gal-positive NPC (22.5%). cyclohexenoesculetin-beta-galactoside 247-251 H3 histone pseudogene 16 Homo sapiens 18-21 33854948-3 2021 A novel fusion enzyme, labeled mTfR-GLB1, was designed to act as a ferry across the BBB by fusing beta-gal to the mouse monoclonal antibody against the mouse transferrin receptor and tested in a murine model of GM1-gangliosidosis (beta-gal-/-). cyclohexenoesculetin-beta-galactoside 102-106 galactosidase, beta 1 Mus musculus 36-40 32544584-3 2020 The results indicated: CPS-1 was mainly composed of Ara, Gal, Glc, Xyl, Man, GalA and GlcA in a molar ratio of 1.23:2.14:0.67:0.2:0.29:0.16:0.04 with molecular weight of 3297 kDa. cyclohexenoesculetin-beta-galactoside 57-60 carbamoyl-phosphate synthase 1 Homo sapiens 23-28 33460651-5 2021 Human Gb3/CD77 synthase was long believed to transfer Gal only to GSL acceptors, therefore its GSL products were, by default, considered the only human Stx receptors. cyclohexenoesculetin-beta-galactoside 54-57 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 6-9 33460651-5 2021 Human Gb3/CD77 synthase was long believed to transfer Gal only to GSL acceptors, therefore its GSL products were, by default, considered the only human Stx receptors. cyclohexenoesculetin-beta-galactoside 54-57 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 10-23 33692491-9 2021 Inferring the gene regulatory networks after nerve injury, we revealed that activated transcription factors Atf3 and Egr1 in SNIICs could enhance Gal expression while activated Cpeb1 in SNIIC2 might suppress Mrgprd expression within 2 days after SNI. cyclohexenoesculetin-beta-galactoside 146-149 activating transcription factor 3 Mus musculus 108-112 33692491-9 2021 Inferring the gene regulatory networks after nerve injury, we revealed that activated transcription factors Atf3 and Egr1 in SNIICs could enhance Gal expression while activated Cpeb1 in SNIIC2 might suppress Mrgprd expression within 2 days after SNI. cyclohexenoesculetin-beta-galactoside 146-149 early growth response 1 Mus musculus 117-121 32727849-4 2020 Here, we demonstrate that beta-Gal negatively regulates NEU1 levels in lysosomes by competitively displacing this labile sialidase from PPCA. cyclohexenoesculetin-beta-galactoside 30-34 neuraminidase 1 Homo sapiens 56-60 32907757-6 2020 This anti-Gal mediated effective uptake of vaccines by APC results in 10-200-fold higher anti-viral immune response and in 8-fold higher survival rate following challenge with a lethal dose of live influenza virus, than same vaccines lacking alpha-gal epitopes. cyclohexenoesculetin-beta-galactoside 10-13 APC regulator of WNT signaling pathway Homo sapiens 55-58 32727849-4 2020 Here, we demonstrate that beta-Gal negatively regulates NEU1 levels in lysosomes by competitively displacing this labile sialidase from PPCA. cyclohexenoesculetin-beta-galactoside 30-34 cathepsin A Homo sapiens 136-140 32957489-10 2020 We have reported that DimLex adopts two conformations around the beta-d-GlcNAc-(1 3)-d-Gal bond connecting the Lex trisaccharides. cyclohexenoesculetin-beta-galactoside 87-90 fucosyltransferase 4 Homo sapiens 25-28 32567311-2 2020 The synthetic strategy relies on a chemical alpha(2,6)-sialylation at the internal GalNAc unit of a Gb5 pentasaccharide backbone that furnishes a Neu5Acalpha(2,6)GalNAc-linked hexasaccharide, suitable for an enzymatic alpha(2,3)-sialylation of the terminal Gal residue to construct a heptasaccharide glycan. cyclohexenoesculetin-beta-galactoside 83-86 G protein subunit beta 5 Homo sapiens 100-103 32339574-5 2020 Both GPS-1 and GPS-2 had branches attaching on O-3 of (1 6)-GalA or O-4 of (1 2)-Rha and terminated by either Ara or Gal. cyclohexenoesculetin-beta-galactoside 62-65 G protein pathway suppressor 1 Homo sapiens 5-10 32339574-5 2020 Both GPS-1 and GPS-2 had branches attaching on O-3 of (1 6)-GalA or O-4 of (1 2)-Rha and terminated by either Ara or Gal. cyclohexenoesculetin-beta-galactoside 62-65 G protein pathway suppressor 2 Homo sapiens 15-20 32732027-3 2020 GalKAmu displayed broad substrate tolerance, with catalytic activity towards Gal (100 %), GalN (100 %), GalA (20.2 %), Glc (52.5 %), GlcNAc (15.5 %), Xyl (<5%), ManNAc (58 %), ManF (37.4 %) and l-Glc (80 %). cyclohexenoesculetin-beta-galactoside 0-3 galactosidase alpha Homo sapiens 104-108 32732027-3 2020 GalKAmu displayed broad substrate tolerance, with catalytic activity towards Gal (100 %), GalN (100 %), GalA (20.2 %), Glc (52.5 %), GlcNAc (15.5 %), Xyl (<5%), ManNAc (58 %), ManF (37.4 %) and l-Glc (80 %). cyclohexenoesculetin-beta-galactoside 0-3 mesencephalic astrocyte derived neurotrophic factor Homo sapiens 176-180 32663509-5 2020 While overexpression of B4GALT1 slightly enhanced the levels of large glycans on recombinant EPO, overexpression of B3GNT2 in EPO-expressing CHO cells significantly decreased the recombinant EPO LacNAc content, resulting in N-glycans terminating primarily with GlcNAc structures, a limited number of Gals, and nearly undetectable sialylation, which was also observed in sialyltransferases knock-out-B3GNT2 overexpression cell lines. cyclohexenoesculetin-beta-galactoside 300-304 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 Cricetulus griseus 116-122 32663509-5 2020 While overexpression of B4GALT1 slightly enhanced the levels of large glycans on recombinant EPO, overexpression of B3GNT2 in EPO-expressing CHO cells significantly decreased the recombinant EPO LacNAc content, resulting in N-glycans terminating primarily with GlcNAc structures, a limited number of Gals, and nearly undetectable sialylation, which was also observed in sialyltransferases knock-out-B3GNT2 overexpression cell lines. cyclohexenoesculetin-beta-galactoside 300-304 erythropoietin Cricetulus griseus 126-129 32663509-5 2020 While overexpression of B4GALT1 slightly enhanced the levels of large glycans on recombinant EPO, overexpression of B3GNT2 in EPO-expressing CHO cells significantly decreased the recombinant EPO LacNAc content, resulting in N-glycans terminating primarily with GlcNAc structures, a limited number of Gals, and nearly undetectable sialylation, which was also observed in sialyltransferases knock-out-B3GNT2 overexpression cell lines. cyclohexenoesculetin-beta-galactoside 300-304 erythropoietin Cricetulus griseus 126-129 32502344-0 2020 Dual-Probe Approach for Mass Spectrometric Quantification of MUC1-Specific Terminal Gal/GalNAc In Situ. cyclohexenoesculetin-beta-galactoside 84-87 mucin 1, cell surface associated Homo sapiens 61-65 32502344-7 2020 Herein, we developed a dual-probe approach for mass spectrometric quantification of protein-specific glycosylation using the terminal galactose/N-acetylgalactosamine (Gal/GalNAc) of MUC1 as a model. cyclohexenoesculetin-beta-galactoside 167-170 mucin 1, cell surface associated Homo sapiens 182-186 32502344-13 2020 The mass response of the reporter peptide represented the amount of MUC1-specific terminal Gal/GalNAc. cyclohexenoesculetin-beta-galactoside 91-94 mucin 1, cell surface associated Homo sapiens 68-72 32502344-14 2020 This dual-probe approach was applied for in situ detection of MUC1-specific terminal Gal/GalNAc in three human breast cancer cell lines and 32 pairs of matched breast cancer tissue samples. cyclohexenoesculetin-beta-galactoside 85-88 mucin 1, cell surface associated Homo sapiens 62-66 32502344-15 2020 The relationship between MUC1-specific terminal Gal/GalNAc expression and breast cancer diagnosis/prognosis was also assessed. cyclohexenoesculetin-beta-galactoside 48-51 mucin 1, cell surface associated Homo sapiens 25-29 31756475-7 2020 Gal might be attached to the backbone as a side chain or bound to the linear beta-1,3-D-Glcp side chain. cyclohexenoesculetin-beta-galactoside 0-3 immunoglobulin kappa variable 2D-18 (pseudogene) Homo sapiens 77-85 32239931-3 2020 The integration of localized chemical remodeling and quantitative electrochemistry allows the proof-of-concept QLA examination of exosomal mucin 1 (MUC1)-specific terminal galactose/N-acetylgalactosamine (Gal/GalNAc). cyclohexenoesculetin-beta-galactoside 205-208 mucin 1, cell surface associated Homo sapiens 139-146 32088228-4 2020 Ion chromatography (IC) determined that PTP was mainly composed of Ara:Gal:Glu:Man:GlcA:GalA in a molar ratio of 6.98:16.56:7.25:2.04:1:4.16. cyclohexenoesculetin-beta-galactoside 71-74 protein tyrosine phosphatase receptor type U Homo sapiens 40-43 32239931-3 2020 The integration of localized chemical remodeling and quantitative electrochemistry allows the proof-of-concept QLA examination of exosomal mucin 1 (MUC1)-specific terminal galactose/N-acetylgalactosamine (Gal/GalNAc). cyclohexenoesculetin-beta-galactoside 205-208 mucin 1, cell surface associated Homo sapiens 148-152 32239931-4 2020 In combination with sialic acid (Sia) cleavage manipulation for the exposure of originally capped Gal/GalNAc, QLA has revealed distinct MUC1-specific sialylation capping ratios for MCF-7 and MDA-MB-231 exosomes, as well as when compared to parent cells. cyclohexenoesculetin-beta-galactoside 98-101 mucin 1, cell surface associated Homo sapiens 136-140 31877766-6 2019 In the retrospective cohort, urinary Gal3C-S lectin reactive- (Gal3C-S-) OPN/full-length-OPN, was significantly higher in the stone forming urolithiasis patients than in the healthy volunteers (p < 0.0001), with good discrimination (AUC, 0.953), 90% sensitivity, and 92% specificity. cyclohexenoesculetin-beta-galactoside 37-44 secreted phosphoprotein 1 Homo sapiens 63-76 31722267-3 2020 The GGTA1 gene is responsible for the generation of Gal epitopes on the surface of porcine cells, triggering hyperacute immune rejection in preclinical porcine-to-human xenotransplantation. cyclohexenoesculetin-beta-galactoside 52-55 glycoprotein alpha-galactosyltransferase 1 (inactive) Homo sapiens 4-9 31877766-6 2019 In the retrospective cohort, urinary Gal3C-S lectin reactive- (Gal3C-S-) OPN/full-length-OPN, was significantly higher in the stone forming urolithiasis patients than in the healthy volunteers (p < 0.0001), with good discrimination (AUC, 0.953), 90% sensitivity, and 92% specificity. cyclohexenoesculetin-beta-galactoside 37-44 secreted phosphoprotein 1 Homo sapiens 73-76 31877766-8 2019 In the prospective longitudinal follow-up study, 92.8% of the stone-free urolithiasis group had Gal3C-S-OPN/full-length-OPN levels below the cutoff value after ureteroscopic lithotripsy (URS), whereas 71.4% of the residual-stone urolithiasis group did not show decreased levels after URS. cyclohexenoesculetin-beta-galactoside 96-103 secreted phosphoprotein 1 Homo sapiens 104-107 31877766-9 2019 Therefore, Gal3C-S-OPN/full-length-OPN levels could be used as a urolithiasis biomarker. cyclohexenoesculetin-beta-galactoside 11-18 secreted phosphoprotein 1 Homo sapiens 19-22 30936009-3 2019 Monosaccharide composition analysis based on GC-MS showed that MRP-1 mainly consisted of Rha, Ara, Fru, Xyl, Man and Gal in the molar ratio of 1.5:2.0:3.1:6.0:5.3:1.1. cyclohexenoesculetin-beta-galactoside 117-120 prolactin family 2, subfamily c, member 2 Mus musculus 63-68 31366978-1 2019 Infant gut-associated bifidobacteria has a metabolic pathway that specifically utilizes lacto-N-biose I (Gal-beta1,3-GlcNAc) and galacto-N-biose (Gal-beta1,3-GalNAc) from human milk and mucin glycans. cyclohexenoesculetin-beta-galactoside 105-109 LOC100508689 Homo sapiens 186-191 31397399-7 2019 Subclass enzyme-linked immunosorbent assay analysis further revealed enhanced IgG2 and IgG3 anti-gal titers in patients with PKDL compared to control subjects. cyclohexenoesculetin-beta-galactoside 97-100 immunoglobulin heavy constant gamma 3 (G3m marker) Homo sapiens 87-91 31128121-3 2019 GAL(1-15) is also able to enhance the antidepressant effects induced by Fluoxetine (FLX) in the forced swimming test through interaction between GALR1-GALR2 and 5-HT1A receptors that induced changes in the binding characteristics and mRNA of the 5-HT1AR in the hippocampus. cyclohexenoesculetin-beta-galactoside 0-3 galanin receptor 1 Rattus norvegicus 145-150 31128121-3 2019 GAL(1-15) is also able to enhance the antidepressant effects induced by Fluoxetine (FLX) in the forced swimming test through interaction between GALR1-GALR2 and 5-HT1A receptors that induced changes in the binding characteristics and mRNA of the 5-HT1AR in the hippocampus. cyclohexenoesculetin-beta-galactoside 0-3 galanin receptor 2 Rattus norvegicus 151-156 31128121-3 2019 GAL(1-15) is also able to enhance the antidepressant effects induced by Fluoxetine (FLX) in the forced swimming test through interaction between GALR1-GALR2 and 5-HT1A receptors that induced changes in the binding characteristics and mRNA of the 5-HT1AR in the hippocampus. cyclohexenoesculetin-beta-galactoside 0-3 5-hydroxytryptamine receptor 1A Rattus norvegicus 161-167 31128121-7 2019 GALR2 was involved in these effects, since the specific GALR2 antagonist M871 blocked GAL(1-15) mediated actions at behavioral level. cyclohexenoesculetin-beta-galactoside 0-3 galanin receptor 2 Rattus norvegicus 56-61 30553446-9 2019 The numbers of GalNAc and Gal and the Gal/GalNAc ratio in the HR of the IgAN recipients had significantly lower comparing to the IgAD and non-IgAD healthy donors. cyclohexenoesculetin-beta-galactoside 15-18 IGAN1 Homo sapiens 72-76 31242623-3 2019 The analysis of the data demonstrates that monosaccharides Fuc, Man, Glc, and Gal are able to bind DC-SIGN, although with decreasing affinity. cyclohexenoesculetin-beta-galactoside 78-81 CD209 molecule Homo sapiens 99-106 30553856-5 2019 Monosaccharide composition analysis revealed that ARP was composed of Gal, Ara, Glu, Man, Rha and Fuc at a molar ratio of 53.8:21.3:11.7:6.8:4.3:2.2. cyclohexenoesculetin-beta-galactoside 70-73 arginine-glutamic acid dipeptide repeats Homo sapiens 50-53 30553446-9 2019 The numbers of GalNAc and Gal and the Gal/GalNAc ratio in the HR of the IgAN recipients had significantly lower comparing to the IgAD and non-IgAD healthy donors. cyclohexenoesculetin-beta-galactoside 26-29 IGAN1 Homo sapiens 72-76 30553446-10 2019 The decreased Gal/GalNAc ratio in IgAN recipients means the increased ratio of galactose-deficient IgA1. cyclohexenoesculetin-beta-galactoside 14-17 IGAN1 Homo sapiens 34-38 30553446-10 2019 The decreased Gal/GalNAc ratio in IgAN recipients means the increased ratio of galactose-deficient IgA1. cyclohexenoesculetin-beta-galactoside 14-17 immunoglobulin heavy constant alpha 1 Homo sapiens 99-103 30553446-12 2019 Overall, decreased GalNAc and Gal contents in HR could play a material pathogenic role in IgAN. cyclohexenoesculetin-beta-galactoside 19-22 IGAN1 Homo sapiens 90-94 29969638-3 2018 The results of methylation analysis indicated that FPS mainly included 1-linked-glc, 1,4-linked-glc, 1,6-linked-glc, 1,3-linked-gal and 1,3,6-linked-man glycosidic bonds. cyclohexenoesculetin-beta-galactoside 128-131 farnesyl diphosphate synthase Homo sapiens 51-54 30593944-3 2019 ScGalK displayed a broad substrate tolerance, with activity towards Gal, GalN, Gal3D, GalNAc, Man and L-Ara. cyclohexenoesculetin-beta-galactoside 2-5 galanin and GMAP prepropeptide Homo sapiens 73-77 30337628-2 2018 However, whether iGb3S deletion changes Gal epitope expression and immunological properties in animals is still not clear. cyclohexenoesculetin-beta-galactoside 40-43 alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase) Mus musculus 17-22 30337628-9 2018 The data from this study suggest that the iGb3S gene likely contributes to Gal epitope expression, but may have a very weak effect on immunological properties of the iGb3S deficient mice. cyclohexenoesculetin-beta-galactoside 75-78 alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase) Mus musculus 42-47 30086537-4 2018 In addition, reducing GRSF1 increased the activity of a senescence-associated beta-galactosidase (SA-beta-gal) and the production and secretion of the SASP factor interleukin 6 (IL6). cyclohexenoesculetin-beta-galactoside 82-86 G-rich RNA sequence binding factor 1 Homo sapiens 22-27 29894864-5 2018 Treatment with DA also suppressed LPS/D-Gal-induced production of TNF-alpha, phosphorylation of c-jun-N-terminal kinase (JNK), cleavage of caspase-3, up-regulation of hepatic caspase-3, caspase-8, and caspase-9 activities and reduced the count of TUNEL-positive hepatocytes. cyclohexenoesculetin-beta-galactoside 40-43 tumor necrosis factor Mus musculus 66-75 29894864-5 2018 Treatment with DA also suppressed LPS/D-Gal-induced production of TNF-alpha, phosphorylation of c-jun-N-terminal kinase (JNK), cleavage of caspase-3, up-regulation of hepatic caspase-3, caspase-8, and caspase-9 activities and reduced the count of TUNEL-positive hepatocytes. cyclohexenoesculetin-beta-galactoside 40-43 mitogen-activated protein kinase 8 Mus musculus 96-119 29894864-5 2018 Treatment with DA also suppressed LPS/D-Gal-induced production of TNF-alpha, phosphorylation of c-jun-N-terminal kinase (JNK), cleavage of caspase-3, up-regulation of hepatic caspase-3, caspase-8, and caspase-9 activities and reduced the count of TUNEL-positive hepatocytes. cyclohexenoesculetin-beta-galactoside 40-43 caspase 3 Mus musculus 139-148 29894864-5 2018 Treatment with DA also suppressed LPS/D-Gal-induced production of TNF-alpha, phosphorylation of c-jun-N-terminal kinase (JNK), cleavage of caspase-3, up-regulation of hepatic caspase-3, caspase-8, and caspase-9 activities and reduced the count of TUNEL-positive hepatocytes. cyclohexenoesculetin-beta-galactoside 40-43 caspase 3 Mus musculus 175-184 29894864-5 2018 Treatment with DA also suppressed LPS/D-Gal-induced production of TNF-alpha, phosphorylation of c-jun-N-terminal kinase (JNK), cleavage of caspase-3, up-regulation of hepatic caspase-3, caspase-8, and caspase-9 activities and reduced the count of TUNEL-positive hepatocytes. cyclohexenoesculetin-beta-galactoside 40-43 caspase 8 Mus musculus 186-195 29894864-5 2018 Treatment with DA also suppressed LPS/D-Gal-induced production of TNF-alpha, phosphorylation of c-jun-N-terminal kinase (JNK), cleavage of caspase-3, up-regulation of hepatic caspase-3, caspase-8, and caspase-9 activities and reduced the count of TUNEL-positive hepatocytes. cyclohexenoesculetin-beta-galactoside 40-43 caspase 9 Mus musculus 201-210 29481398-5 2018 The expression of canonical Wnt after wounding was analyzed using X-gal staining and quantitative real-time polymerase chain reaction. cyclohexenoesculetin-beta-galactoside 68-71 wingless-type MMTV integration site family, member 3A Mus musculus 28-31 28557363-4 2017 The proof-of-concept protocol developed for MUC1-specific terminal galactose/N-acetylgalactosamine (Gal/GalNAc) combines affinity binding, off-on switchable catalytic activity, and proximity catalysis to create a reactive handle for bioorthogonal labeling and imaging. cyclohexenoesculetin-beta-galactoside 100-103 mucin 1, cell surface associated Homo sapiens 44-48 28844534-9 2017 This is the first report demonstrating the presence in SSTs of the OC-116, OC-17 and OCX36 eggshell matrix proteins, and their concomitant presence with Gal/GalNAc and Glc/GlcNAc glycans, as well as with calcium. cyclohexenoesculetin-beta-galactoside 153-156 matrix extracellular phosphoglycoprotein Gallus gallus 67-80 30135938-6 2017 X-gal staining of GLYT2-Cre/R26R double transgenic mouse brains and spinal cords revealed that the Cre activity was primarily distributed in the brainstem, cerebellum, and spinal cord. cyclohexenoesculetin-beta-galactoside 2-5 solute carrier family 6 (neurotransmitter transporter, glycine), member 5 Mus musculus 18-23 27913116-2 2017 Expression of constitutive mutant of Gal3p or overexpression of wild-type Gal3p activates the GAL switch in the absence of galactose. cyclohexenoesculetin-beta-galactoside 94-97 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 37-42 28461138-6 2017 In addition, X-gal staining combined with immunohistochemistry identified intense signals for ASIC4 transcriptional activity in most of the choline acetyltransferase (ChAT)-positive principal neurons located in the basal forebrain cholinergic nuclei. cyclohexenoesculetin-beta-galactoside 15-18 acid-sensing (proton-gated) ion channel family member 4 Mus musculus 94-99 28288814-7 2017 Importantly, 5-HT1A receptors (5HT1A-R) also participate in the GAL(1-15)/FLX interactions since the 5HT1AR antagonist WAY100635 blocked the behavioral effects in the FST induced by the coadministration of GAL(1-15) and FLX. cyclohexenoesculetin-beta-galactoside 64-67 5-hydroxytryptamine receptor 1A Rattus norvegicus 13-19 28288814-7 2017 Importantly, 5-HT1A receptors (5HT1A-R) also participate in the GAL(1-15)/FLX interactions since the 5HT1AR antagonist WAY100635 blocked the behavioral effects in the FST induced by the coadministration of GAL(1-15) and FLX. cyclohexenoesculetin-beta-galactoside 206-209 5-hydroxytryptamine receptor 1A Rattus norvegicus 13-19 27913116-2 2017 Expression of constitutive mutant of Gal3p or overexpression of wild-type Gal3p activates the GAL switch in the absence of galactose. cyclohexenoesculetin-beta-galactoside 94-97 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 74-79 27913116-6 2017 To understand the mechanism of allosteric transition, we have isolated a triple mutant of Gal3p with V273I, T404A, and N450D substitutions, which, upon overexpression, fails to activate the GAL switch on its own but activates the switch in response to galactose. cyclohexenoesculetin-beta-galactoside 190-193 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 90-95 27329245-9 2017 Of note, treatment with the anti-oxidant reagent NAC significantly suppressed SA-beta-Gal activity in androgen-sensitive human prostate cancer LNCaP cells. cyclohexenoesculetin-beta-galactoside 86-89 synuclein alpha Homo sapiens 49-52 27422836-3 2016 A beta-N-acetylhexosaminidase named BbhI, which belongs to glycoside hydrolase family 20 and was obtained from B. bifidum JCM 1254, possesses the bifunctional property of efficiently transferring both GalNAc and GlcNAc residues through beta1-3 linkage to the Gal residue of lactose. cyclohexenoesculetin-beta-galactoside 201-204 O-GlcNAcase Homo sapiens 2-29 27562100-3 2016 One of the substrates of GALT, galactose-1-phosphate (Gal-1P), accumulates to high levels in affected infants, especially following milk exposure, and has been proposed as the key mediator of acute and long-term pathophysiology in CG. cyclohexenoesculetin-beta-galactoside 54-57 galactose-1-phosphate uridylyltransferase Homo sapiens 25-29 27732642-6 2016 Moreover, H2S safeguards the expression of hTERT in a NAMPT and SIRT1 dependent manner and delays the onset of replicative senescence as evidenced by reduced accumulation of age associated SA-beta-Gal and cessation of proliferation. cyclohexenoesculetin-beta-galactoside 196-200 telomerase reverse transcriptase Homo sapiens 43-48 27422836-3 2016 A beta-N-acetylhexosaminidase named BbhI, which belongs to glycoside hydrolase family 20 and was obtained from B. bifidum JCM 1254, possesses the bifunctional property of efficiently transferring both GalNAc and GlcNAc residues through beta1-3 linkage to the Gal residue of lactose. cyclohexenoesculetin-beta-galactoside 201-204 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 236-243 27453399-3 2016 Mucin-related glycopeptides incorporating these motifs were recognized by the monoclonal antibody (mAb) scFv-SM3, with activities depending on both the hydroxylation pattern (Glc/Gal/GlcNAc/GalNAc) of the sp(2)-iminosugar and the peptide aglycone structure (Ser/Thr). cyclohexenoesculetin-beta-galactoside 179-182 LOC100508689 Homo sapiens 0-5 27453399-3 2016 Mucin-related glycopeptides incorporating these motifs were recognized by the monoclonal antibody (mAb) scFv-SM3, with activities depending on both the hydroxylation pattern (Glc/Gal/GlcNAc/GalNAc) of the sp(2)-iminosugar and the peptide aglycone structure (Ser/Thr). cyclohexenoesculetin-beta-galactoside 179-182 immunglobulin heavy chain variable region Homo sapiens 104-108 27073161-4 2016 It was further suggested that GAL10-ncRNA repression of GAL1-10 promoter leakage tunes the bimodal expression pattern of the GAL network. cyclohexenoesculetin-beta-galactoside 30-33 SNR45 Saccharomyces cerevisiae S288C 36-41 26773500-2 2016 Recently, it was shown that c.631C > G mutation in A4GALT, which causes p.Q211E substitution in the open reading frame of the enzyme, broadens the enzyme specificity, making it able also to synthesize Gal(alpha1-4)GalNAc moiety, which constitutes the defining terminal disaccharide of the NOR antigen (carried by two glycosphingolipids: NOR1 and NOR2). cyclohexenoesculetin-beta-galactoside 204-207 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 54-60 25977259-7 2016 In addition, the number of cells with positive staining by Ki-67 and caspase-3 were significantly increased in GAL groups compared with the control group (p = 0.0001). cyclohexenoesculetin-beta-galactoside 111-114 caspase 3 Rattus norvegicus 69-78 26712695-3 2016 Monosaccharide component analysis indicated that MAP-1 was composed of Rha, Ara, Glu, Gal, and GalA in a molar ratio of 1.1:0.4:0.7:0.5:0.3. cyclohexenoesculetin-beta-galactoside 86-89 mannosidase processing 1 Mus musculus 49-54 26915683-2 2016 After conjugating galactose and CMCS to the surface of Fe3O4-NPs, we observed that Gal-CMCS-Fe3O4-NPs were round with a relatively stable zeta potential of +6.5 mV and an mean hydrodynamic size of 40.1 +- 5.3 nm. cyclohexenoesculetin-beta-galactoside 83-86 cerebral malaria susceptibility in CBA/N Mus musculus 32-36 26915683-2 2016 After conjugating galactose and CMCS to the surface of Fe3O4-NPs, we observed that Gal-CMCS-Fe3O4-NPs were round with a relatively stable zeta potential of +6.5 mV and an mean hydrodynamic size of 40.1 +- 5.3 nm. cyclohexenoesculetin-beta-galactoside 83-86 cerebral malaria susceptibility in CBA/N Mus musculus 87-91 26915683-3 2016 Gal-CMCS-Fe3O4-NPs had strong DNA condensing power in pH 7 solution and were largely nontoxic. cyclohexenoesculetin-beta-galactoside 0-3 cerebral malaria susceptibility in CBA/N Mus musculus 4-8 27128635-5 2016 By redistributing cohesin from the nucleolus to the pericentromere (by deleting SIR2), there is increased presence of the kinetochore protein Mif2 at GAL-CEN and restoration of cell viability. cyclohexenoesculetin-beta-galactoside 150-153 Mif2p Saccharomyces cerevisiae S288C 142-146 26773500-2 2016 Recently, it was shown that c.631C > G mutation in A4GALT, which causes p.Q211E substitution in the open reading frame of the enzyme, broadens the enzyme specificity, making it able also to synthesize Gal(alpha1-4)GalNAc moiety, which constitutes the defining terminal disaccharide of the NOR antigen (carried by two glycosphingolipids: NOR1 and NOR2). cyclohexenoesculetin-beta-galactoside 204-207 immunoglobulin binding protein 1 Homo sapiens 208-216 26773500-2 2016 Recently, it was shown that c.631C > G mutation in A4GALT, which causes p.Q211E substitution in the open reading frame of the enzyme, broadens the enzyme specificity, making it able also to synthesize Gal(alpha1-4)GalNAc moiety, which constitutes the defining terminal disaccharide of the NOR antigen (carried by two glycosphingolipids: NOR1 and NOR2). cyclohexenoesculetin-beta-galactoside 204-207 nuclear receptor subfamily 4 group A member 3 Homo sapiens 340-344 26291713-1 2015 When lactose was incubated with G794A-beta-galactosidase (a variant with a "closed" active site loop that binds transition state analogs well) an allolactose was trapped with its Gal moiety in a (4)H3 conformation, similar to the oxocarbenium ion-like conformation expected of the transition state. cyclohexenoesculetin-beta-galactoside 179-182 galactosidase beta 1 Homo sapiens 38-56 25659691-6 2015 Sulfate groups can occupy positions C-2 and/or sometimes C-3 of Gal residues, but a sulfation at C-4 of the galactofucan could not be excluded. cyclohexenoesculetin-beta-galactoside 64-67 complement C3 Homo sapiens 57-60 26079152-4 2015 We have now developed liver-targeted nanoplexes by conjugating poly(amidoamine) (PAMAM) dendrimers with polyethylene glycol (PEG) and lactobionic acid (Gal) (PAMAM-PEG-Gal) which were complexed with AEG-1 siRNA (PAMAM-AEG-1si). cyclohexenoesculetin-beta-galactoside 152-155 metadherin Mus musculus 199-204 26261081-4 2015 The elevations of serum alanine aminotransferase and aspartate aminotransferase, as well as the abnormal hepatic architecture, verified that oral administration of Seleno-Lentinan (SL2-1) markedly alleviated oxidative damage in the liver of mice induced by D-gal. cyclohexenoesculetin-beta-galactoside 259-262 MAP6 domain containing 1 Mus musculus 181-186 25834926-3 2015 Results showed that the total soluble sugar contents of SAP composed of Man, GlcN, Rha, GalN, GlcUA, Glc, Gal, Xyl and Fuc were more than 85% estimated by the phenol-sulfuric acid assay. cyclohexenoesculetin-beta-galactoside 88-91 SH2 domain containing 1A Homo sapiens 56-59 26675134-6 2015 RESULTS: The Bbeta and gamma chains of acute phase fibrinogen showed a mass decrease of 162 Da (Gal) in some 50% of the molecules, and the Bbeta chain showed an additional decrease corresponding to a further loss of NAcGlc. cyclohexenoesculetin-beta-galactoside 96-99 fibrinogen beta chain Homo sapiens 51-61 25965476-5 2015 Monosaccharide analysis showed that GPA1, GPA2 and GPA3 were all composed of Man, Rha, GlcA, GalA, Glc, Gal, Ara and Fuc, besides, GPA2 and GPA3 also contained Xyl. cyclohexenoesculetin-beta-galactoside 93-96 glycoprotein hormone subunit alpha 2 Homo sapiens 42-46 25395016-5 2015 Compared with treatment of Ad-beta-gal or PBS, Ad-APN treatment markedly reduced inducible nitric oxide synthase (iNOS) protein expression, decreased in nitric oxide/superoxide production, blocked peroxynitrite formation and reversed the progression of atherosclerotic lesions. cyclohexenoesculetin-beta-galactoside 35-38 adiponectin, C1Q and collagen domain containing Mus musculus 50-53 25324212-0 2014 Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin. cyclohexenoesculetin-beta-galactoside 29-32 LOC100508689 Homo sapiens 113-118 25359390-6 2014 In addition, two more glyco-oligoamides with non-cooperative hydrogen-bonding centers, that is, beta-D-Glc-Py-gamma-Py-Ind (3; Glc=glucose), beta-D-Gal-Py-gamma-Py-Ind (4; Gal=galactose), and the model compounds beta-D-Man-Py-NHAc (5) and beta-D-Tal-Py-NHAc (6) were synthesized and studied for comparison. cyclohexenoesculetin-beta-galactoside 148-151 transaldolase 1 Homo sapiens 246-249 25324212-0 2014 Delineating binding modes of Gal/GalNAc and structural elements of the molecular recognition of tumor-associated mucin glycopeptides by the human macrophage galactose-type lectin. cyclohexenoesculetin-beta-galactoside 29-32 C-type lectin domain containing 10A Homo sapiens 146-178 25324212-6 2014 NMR data were complemented with molecular dynamics simulations and Corcema-ST to establish a 3D view on the molecular recognition process between Gal, GalNAc, and the Tn-presenting glycopeptides and MGL. cyclohexenoesculetin-beta-galactoside 146-149 C-type lectin domain containing 10A Homo sapiens 199-202 24852094-5 2014 MTT assays in asialoglycoprotein receptor (ASGP-R) over-expressing HepG2 cells demonstrated that half-maximal inhibitory concentration (IC50) values of Gal-PTX-CLMs decreased from 11.7 to 2.9 to 1.1mug/mL with increasing Gal contents from 10% to 20% to 30%, supporting receptor-mediated endocytosis mechanism. cyclohexenoesculetin-beta-galactoside 152-155 asialoglycoprotein receptor 1 Homo sapiens 43-49 24472508-4 2014 And AEP-2 mainly contained Ara, Man, Gal, Glc and GalA. cyclohexenoesculetin-beta-galactoside 37-40 spermatogenesis associated 32 Homo sapiens 4-9 24785355-9 2014 We suggest that the asymmetric expression pattern between GAL1 and GAL3 results in the ability of S. cerevisiae to activate the GAL pathway by conferring nongenetic heterogeneity. cyclohexenoesculetin-beta-galactoside 58-61 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 67-71 25135592-5 2014 We demonstrate that the GAL switch becomes independent of GAL3 by altering the interaction between Gal4p and Gal80p without altering the configuration of UASG . cyclohexenoesculetin-beta-galactoside 24-27 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 99-104 25135592-5 2014 We demonstrate that the GAL switch becomes independent of GAL3 by altering the interaction between Gal4p and Gal80p without altering the configuration of UASG . cyclohexenoesculetin-beta-galactoside 24-27 transcription regulator GAL80 Saccharomyces cerevisiae S288C 109-115 25170304-1 2014 The C-type lectin receptor mMGL is expressed exclusively by myeloid antigen presenting cells (APC) such as dendritic cells (DC) and macrophages (Mphi), and it mediates binding to glycoproteins carrying terminal galactose and alpha- or beta-N-acetylgalactosamine (Gal/GalNAc) residues. cyclohexenoesculetin-beta-galactoside 263-266 C-type lectin domain family 10, member A Mus musculus 27-31 24785355-3 2014 The mechanism ensuring that GAL1 is eventually expressed to turn on the GAL switch in the gal3 strain remains a paradox. cyclohexenoesculetin-beta-galactoside 28-31 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 90-94 24430555-10 2014 Gal epitopes on GGTA1 null pig cells were completely eliminated from the cell membrane. cyclohexenoesculetin-beta-galactoside 0-3 N-acetyllactosaminide alpha-1,3-galactosyltransferase Sus scrofa 16-21 24644545-3 2014 (Marciniak J, Zalewska A, Popko J, Zwierz K, 2006, Clin Chem Lab Med 44: 933-937) method for determination of HEX and GLU activity in synovial fluid, and for determination of: HEX and GLU, as well as MAN, GAL, and FUC activity in human saliva. cyclohexenoesculetin-beta-galactoside 205-208 hematopoietically expressed homeobox Homo sapiens 110-113 24225957-5 2014 In this Gb3 analog,-GalNAc replaces the terminal-Gal residue. cyclohexenoesculetin-beta-galactoside 20-23 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 8-11 23621358-5 2013 By in vitro experiments, the specificity of RBV tripalmitate-loaded PHEA-EDA-PLA-GAL micelles toward HepG2 was demonstrated by using a competitive inhibition assay in the presence of free GAL. cyclohexenoesculetin-beta-galactoside 81-84 ectodysplasin A Homo sapiens 73-76 24318810-4 2014 We reveal that 6-chloro-3-indoxyl-beta-D-galactopyranoside (S-gal) is a more sensitive substrate for beta-gal activity than 5-bromo-4-chloro-3-indolyl-beta-D-galactoside (X-gal). cyclohexenoesculetin-beta-galactoside 60-65 galactosidase, beta 1 Mus musculus 101-109