PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 8212570-5 1993 Unique features of BICP4 were two large clusters of glutamic acid residues near the end of region 3, and the displacement of a polyserine tract to region 5, which in all other ICP4 homologs residues near the end of region 1. polyserine 127-137 transcriptional regulator ICP4 Bovine alphaherpesvirus 1 19-24 24216761-7 2014 Using comparative proteomics of wild-type (WT) and KSSR mutant CK2beta, we identified an uncharacterized cellular protein, C18orf25/ARKL1, that also binds CK2beta through the KSSR motif and show that this involves a polyserine sequence resembling the CK2beta binding sequence in EBNA1. polyserine 216-226 EBNA-1 Human gammaherpesvirus 4 279-284 32240172-4 2020 RAN translation of the CAG sense and CUG anti-sense RNAs produces six distinct repeat peptides: polyalanine (polyAla, from both CAG and CUG repeats), polyserine (polySer), polyleucine (polyLeu), polycysteine (polyCys), and polyglutamine (polyGln). polyserine 150-160 RAN, member RAS oncogene family Homo sapiens 0-3 32240172-4 2020 RAN translation of the CAG sense and CUG anti-sense RNAs produces six distinct repeat peptides: polyalanine (polyAla, from both CAG and CUG repeats), polyserine (polySer), polyleucine (polyLeu), polycysteine (polyCys), and polyglutamine (polyGln). polyserine 162-169 RAN, member RAS oncogene family Homo sapiens 0-3 31740453-8 2020 The END-1,3 proteins share a region upstream of their zinc finger and an unusual amino-terminal poly-serine domain exhibiting high codon bias. polyserine 96-107 GATA-type domain-containing protein Caenorhabditis elegans 4-9 26578877-4 2015 In addition, WAG-HCN1 has a stretch of six amino acids, directly following the deletion, where the wild-type sequence (GNSVCF) is changed to a polyserine motif. polyserine 143-153 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 Rattus norvegicus 17-21 35102230-1 2022 Repeat-associated non-AUG (RAN) translation of mRNAs/transcripts responsible for polyglutamine (polyQ) diseases may generate peptides containing different mono amino acid tracts such as polyserine (polyS) and polyleucine (polyL). polyserine 186-196 RAN, member RAS oncogene family Mus musculus 27-30 35102230-1 2022 Repeat-associated non-AUG (RAN) translation of mRNAs/transcripts responsible for polyglutamine (polyQ) diseases may generate peptides containing different mono amino acid tracts such as polyserine (polyS) and polyleucine (polyL). polyserine 198-203 RAN, member RAS oncogene family Mus musculus 27-30 35102230-3 2022 However, whether the RAN translation-related polyS and polyL have the ability to propagate remains unclear, and if they do, whether the exogenous polyS and polyL exert toxicity on the recipient cells is also not known yet. polyserine 45-50 RAN, member RAS oncogene family Mus musculus 21-24 35102230-9 2022 Thus, the RAN translation-related proteins containing polyS and polyL have the potential to propagate and the proteins generated by all polyQ diseases might exert universal toxicity in the recipient cells. polyserine 54-59 RAN, member RAS oncogene family Mus musculus 10-13 30387551-0 2018 The Golgi "casein kinase" Fam20C is a genuine "phosvitin kinase" and phosphorylates polyserine stretches devoid of the canonical consensus. polyserine 84-94 FAM20C golgi associated secretory pathway kinase Gallus gallus 26-32 30387551-0 2018 The Golgi "casein kinase" Fam20C is a genuine "phosvitin kinase" and phosphorylates polyserine stretches devoid of the canonical consensus. polyserine 84-94 Casein kinase II subunit beta Gallus gallus 47-56 28750098-10 2017 We further studied a poly-serine stretch present in the N-terminal region of MSSN and observed that the voltage-activation curves of BKCa channels either containing or lacking this poly-serine stretch were leftward shifted by beta1-subunit in a similar way. polyserine 21-32 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 226-231 28750098-10 2017 We further studied a poly-serine stretch present in the N-terminal region of MSSN and observed that the voltage-activation curves of BKCa channels either containing or lacking this poly-serine stretch were leftward shifted by beta1-subunit in a similar way. polyserine 181-192 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 226-231 24216761-5 2014 We show that the EBNA1-CK2beta interaction is primed by phosphorylation of EBNA1 on S393 (within a polyserine region). polyserine 99-109 EBNA-1 Human gammaherpesvirus 4 17-22 24216761-5 2014 We show that the EBNA1-CK2beta interaction is primed by phosphorylation of EBNA1 on S393 (within a polyserine region). polyserine 99-109 casein kinase 2 beta Homo sapiens 23-30 24216761-5 2014 We show that the EBNA1-CK2beta interaction is primed by phosphorylation of EBNA1 on S393 (within a polyserine region). polyserine 99-109 EBNA-1 Human gammaherpesvirus 4 75-80 23688307-6 2013 In correlation with the observed variations in the subnuclear distribution of Jmjd6, the structure of Jmjd6 oligomers in vitro changes in the absence of the polyS domain, possibly reflecting the role of the polyS domain in nuclear/nucleolar shuttling of Jmjd6. polyserine 207-212 jumonji domain containing 6, arginine demethylase and lysine hydroxylase Homo sapiens 102-107 24216761-7 2014 Using comparative proteomics of wild-type (WT) and KSSR mutant CK2beta, we identified an uncharacterized cellular protein, C18orf25/ARKL1, that also binds CK2beta through the KSSR motif and show that this involves a polyserine sequence resembling the CK2beta binding sequence in EBNA1. polyserine 216-226 casein kinase 2 beta Homo sapiens 63-70 24216761-7 2014 Using comparative proteomics of wild-type (WT) and KSSR mutant CK2beta, we identified an uncharacterized cellular protein, C18orf25/ARKL1, that also binds CK2beta through the KSSR motif and show that this involves a polyserine sequence resembling the CK2beta binding sequence in EBNA1. polyserine 216-226 chromosome 18 open reading frame 25 Homo sapiens 123-131 24216761-7 2014 Using comparative proteomics of wild-type (WT) and KSSR mutant CK2beta, we identified an uncharacterized cellular protein, C18orf25/ARKL1, that also binds CK2beta through the KSSR motif and show that this involves a polyserine sequence resembling the CK2beta binding sequence in EBNA1. polyserine 216-226 chromosome 18 open reading frame 25 Homo sapiens 132-137 24216761-7 2014 Using comparative proteomics of wild-type (WT) and KSSR mutant CK2beta, we identified an uncharacterized cellular protein, C18orf25/ARKL1, that also binds CK2beta through the KSSR motif and show that this involves a polyserine sequence resembling the CK2beta binding sequence in EBNA1. polyserine 216-226 casein kinase 2 beta Homo sapiens 155-162 24216761-7 2014 Using comparative proteomics of wild-type (WT) and KSSR mutant CK2beta, we identified an uncharacterized cellular protein, C18orf25/ARKL1, that also binds CK2beta through the KSSR motif and show that this involves a polyserine sequence resembling the CK2beta binding sequence in EBNA1. polyserine 216-226 casein kinase 2 beta Homo sapiens 155-162 23688307-0 2013 The polyserine domain of the lysyl-5 hydroxylase Jmjd6 mediates subnuclear localization. polyserine 4-14 jumonji domain containing 6, arginine demethylase and lysine hydroxylase Homo sapiens 49-54 23688307-3 2013 In the present study we show that an alternatively spliced version of Jmjd6 lacking the polyS (polyserine) domain localizes to the nucleolus, predominantly in the fibrillar centre. polyserine 88-93 jumonji domain containing 6, arginine demethylase and lysine hydroxylase Homo sapiens 70-75 23688307-3 2013 In the present study we show that an alternatively spliced version of Jmjd6 lacking the polyS (polyserine) domain localizes to the nucleolus, predominantly in the fibrillar centre. polyserine 95-105 jumonji domain containing 6, arginine demethylase and lysine hydroxylase Homo sapiens 70-75 23688307-4 2013 Jmjd6 with the polyS domain deleted also interacts with nucleolar proteins. polyserine 15-20 jumonji domain containing 6, arginine demethylase and lysine hydroxylase Homo sapiens 0-5 23688307-6 2013 In correlation with the observed variations in the subnuclear distribution of Jmjd6, the structure of Jmjd6 oligomers in vitro changes in the absence of the polyS domain, possibly reflecting the role of the polyS domain in nuclear/nucleolar shuttling of Jmjd6. polyserine 207-212 jumonji domain containing 6, arginine demethylase and lysine hydroxylase Homo sapiens 102-107 21423665-5 2011 A recent advance reveals that RNA transcripts with expanded CAG repeats can be translated in the complete absence of a starting ATG, and this Repeat Associated Non-ATG translation (RAN-translation) occurs across expanded CAG repeats in all reading frames (CAG, AGC, and GCA) to produce homopolymeric proteins of long polyglutamine, polyserine, and polyalanine tracts. polyserine 332-342 RAN, member RAS oncogene family Homo sapiens 181-184 22573762-0 2012 A vitellogenin polyserine cleavage site: highly disordered conformation protected from proteolysis by phosphorylation. polyserine 15-25 vitellogenin Apis mellifera 2-14 20346000-7 2010 A previously unidentified insertion of three bases in a region coding for a polyserine cluster in exon 1 of the HDAC2 gene was identified in 6/32 adenomas. polyserine 76-86 histone deacetylase 2 Homo sapiens 112-117 16877497-7 2006 The polyserine tract within the phosphatidylserine receptor protein is used as an excellent example of one such case. polyserine 4-14 jumonji domain containing 6, arginine demethylase and lysine hydroxylase Homo sapiens 32-59 19582790-4 2009 Three distinct motifs can be discerned in the SRrp37 protein: (1) a serine-arginine (SR) dipeptide enriched domain, (2) a polyserine stretch, and (3) a potential nucleolar localization signal comprising a long array of basic amino acids. polyserine 122-132 ADP ribosylation factor like GTPase 6 interacting protein 4 Homo sapiens 46-52 16801344-9 2006 This may be relevant to the pathogenesis of human Huntington"s disease, as we have previously shown that both polyserine and polyalanine-containing proteins are modifiers of mutant huntingtin toxicity, with low expression levels of polyalanine-containing proteins having a protective effect. polyserine 110-120 huntingtin Homo sapiens 181-191 11759817-5 2001 No tumor-specific mutation was detected, but polymorphisms were identified in E2F-1 exon 5 and in the polyserine tract of E2F-4. polyserine 102-112 E2F transcription factor 4 Homo sapiens 122-127 12917402-10 2003 Our results suggest that the polyserine (S) domain is most likely the site of phosphorylation in ERD14 responsible for the activation of calcium binding. polyserine 29-39 Dehydrin family protein Arabidopsis thaliana 97-102 14578391-11 2003 Analysis of the Pnn motifs using two-hybrid system assays demonstrated that the polyserine/RS motif within Pnn plays a central but not exclusive role in mediating molecular interactions with identified SR-rich proteins. polyserine 80-90 pinin, desmosome associated protein Homo sapiens 16-19 14578391-11 2003 Analysis of the Pnn motifs using two-hybrid system assays demonstrated that the polyserine/RS motif within Pnn plays a central but not exclusive role in mediating molecular interactions with identified SR-rich proteins. polyserine 80-90 pinin, desmosome associated protein Homo sapiens 107-110 12213201-5 2002 A 27-bp trinucleotide repeat (CAG)(9) encoding polyserine was found in human BHLHB5, but only one CAG was found at the corresponding position in the mouse Bhlhb5 and hamster BETA3 genes. polyserine 47-57 basic helix-loop-helix family member e22 Homo sapiens 77-83 10668804-4 2000 SRm300 also contains a novel and highly conserved N-terminal domain, several unique repeated motifs rich in S, R, and proline residues, and two very long polyserine tracts. polyserine 154-164 serine/arginine repetitive matrix 2 Homo sapiens 0-6