PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
30959081-3	2019	In the current study, inhibitory effects on AGEs formation were investigated using bio-enzymatically synthesized nanoformulations of gold (AuNPs) and silver (AgNPs) by physiologically important enzyme, beta galactosidase.	aunps	139-144	galactosidase beta 1	Homo sapiens	202-220
31082647-8	2019	The colour response of the electrochromic cell was also CEA concentration dependent and more sensitive when the hybrid device was set-up with a photoanode with AuNPs.	aunps	160-165	CEA cell adhesion molecule 3	Homo sapiens	56-59
30862041-7	2019	In-situ real time circular dichroism (CD) spectra showed that L-NIBC-AuNPs could inhibit the conformation transition process of amylin from random coils to alpha-helix, while D-NIBC-AuNPs could only delay but not prevent the formation of alpha-helix; however, they could inhibit the further conformation transition process of amylin from alpha-helix to beta-sheet.	aunps	69-74	islet amyloid polypeptide	Homo sapiens	128-134
30862041-7	2019	In-situ real time circular dichroism (CD) spectra showed that L-NIBC-AuNPs could inhibit the conformation transition process of amylin from random coils to alpha-helix, while D-NIBC-AuNPs could only delay but not prevent the formation of alpha-helix; however, they could inhibit the further conformation transition process of amylin from alpha-helix to beta-sheet.	aunps	69-74	islet amyloid polypeptide	Homo sapiens	326-332
28471199-8	2017	RESULTS: Chitosan nanotransporter with anthracycline antibiotics (CHIT-Zn-DOXO-Fe2O3-AuNPs) was designed and subsequently studied by biophysical methods.	aunps	85-90	chitinase 1	Homo sapiens	66-70
29191423-6	2018	The anodic and cathodic peak potentials of Cyt c/CS-MPA-AuNPs/SAMs-Au electrode were at 0.006V and -0.043V (vs. Ag/AgCl), respectively.	aunps	56-61	cytochrome c, somatic	Homo sapiens	43-48
29191423-6	2018	The anodic and cathodic peak potentials of Cyt c/CS-MPA-AuNPs/SAMs-Au electrode were at 0.006V and -0.043V (vs. Ag/AgCl), respectively.	aunps	56-61	methionine adenosyltransferase 1A	Homo sapiens	62-66
30298819-2	2019	The gold nanoprobe (AuNPs-peptide-Ru1) consisted of a specific peptide tagged with a ruthenium(II) complex (Ru1) and gold nanoparticles (AuNPs) conjugated with the peptide via the strong Au-S bond between the AuNPs surface and the thiol group of the peptide.	aunps	20-25	Scm like with four mbt domains 1	Homo sapiens	34-37
21752633-1	2011	A novel nanoparticle-based electrochemiluminescence (ECL) immunosensor was designed for highly sensitive and selective detection of human cardiac troponin I (cTnI), an important Acute Myocardial Infarction (AMI)-related biomarker, by using N-(aminobutyl)-N-(ethylisoluminol)-functionalized gold nanoparticles (ABEI-AuNPs) as labels.	aunps	315-320	troponin I3, cardiac type	Homo sapiens	138-156
28098753-3	2017	In this work, we developed a lactate biosensor based on the immobilization of lactate oxidase (LOx) onto N,N"-Bis(3,4-dihydroxybenzylidene) -1,2-diaminobenzene Schiff base tetradentate ligand-modified gold nanoparticles (3,4DHS-AuNPs) deposited onto screen-printed carbon electrodes, which exhibit a potent electrocatalytic effect towards hydrogen peroxide oxidation/reduction.	aunps	228-233	lysyl oxidase	Homo sapiens	78-93
28098753-3	2017	In this work, we developed a lactate biosensor based on the immobilization of lactate oxidase (LOx) onto N,N"-Bis(3,4-dihydroxybenzylidene) -1,2-diaminobenzene Schiff base tetradentate ligand-modified gold nanoparticles (3,4DHS-AuNPs) deposited onto screen-printed carbon electrodes, which exhibit a potent electrocatalytic effect towards hydrogen peroxide oxidation/reduction.	aunps	228-233	lysyl oxidase	Homo sapiens	95-98
27619837-9	2016	STATEMENT OF SIGNIFICANCE: Due to the low ability to cross the blood-brain barrier (BBB) and non-specific interactions with metal ions necessary for normal cellular processes of metal chelator or Abeta inhibitors, we created a novel gold nanoparticle-capped mesoporous silica (MSN-AuNPs)-based H2O2-responsive controlled release system for targeted delivery of the metal chelator CQ and AuNPs (Abeta inhibitor).	aunps	281-286	amyloid beta precursor protein	Homo sapiens	196-201
27619837-10	2016	In this system, CQ and AuNPs are released only upon exposure to conditions in which H2O2 levels are high, such as those in Abeta plaques.	aunps	23-28	amyloid beta precursor protein	Homo sapiens	123-128
27101322-4	2016	When gold nanoparticles/graphene oxide (AuNPs/GO) nanocomposites were modified on the aptamer through the S-Au bond to form a sandwich-like structure, the ECL resonance energy transfer (ECL-RET) could occur between Ru(bpy)3(2+) and AuNPs/GO nanocomposites, resulting in an apparent decrease of ECL signal.	aunps	40-45	ret proto-oncogene	Homo sapiens	190-193
27101322-4	2016	When gold nanoparticles/graphene oxide (AuNPs/GO) nanocomposites were modified on the aptamer through the S-Au bond to form a sandwich-like structure, the ECL resonance energy transfer (ECL-RET) could occur between Ru(bpy)3(2+) and AuNPs/GO nanocomposites, resulting in an apparent decrease of ECL signal.	aunps	232-237	ret proto-oncogene	Homo sapiens	190-193
25290645-2	2015	In this work, a novel method for the determination of MUC 1 in serum was developed based on a sandwich-type electrochemical aptasensor, which combined a dual signal amplification strategy of poly(o-phenylenediamine)-Au nanoparticles (PoPD-AuNPs) hybrid film as carrier and AuNPs functionalized silica/multiwalled carbon nanotubes core-shell nanocomposites (AuNPs/SiO2@MWCNTs) as tracing tag.	aunps	239-244	mucin 1, cell surface associated	Homo sapiens	54-59
21752633-1	2011	A novel nanoparticle-based electrochemiluminescence (ECL) immunosensor was designed for highly sensitive and selective detection of human cardiac troponin I (cTnI), an important Acute Myocardial Infarction (AMI)-related biomarker, by using N-(aminobutyl)-N-(ethylisoluminol)-functionalized gold nanoparticles (ABEI-AuNPs) as labels.	aunps	315-320	troponin I3, cardiac type	Homo sapiens	158-162
20337374-3	2009	The AuNPs/CPNEs combining catalytic activity of ferrocene to ascorbic acid were used for the fabrication of an ultrasensitive aptamer sensor for thrombin detection.	aunps	4-9	coagulation factor II, thrombin	Homo sapiens	145-153
21671657-3	2011	AuNPs of various sizes (20-300 nm) and shapes (spheres, triangular plates, and polygons) can be obtained upon modulating the ratio of gold ions to the Rev peptide.	aunps	0-5	REV3 like, DNA directed polymerase zeta catalytic subunit	Mus musculus	151-154
20973534-9	2010	Specificity of trastuzumab-PEG-AuNPs for HER-2 and internalization in SK-BR-3 cells was demonstrated by comparing the uptake of trastuzumab-PEG-AuNPs or PEG-AuNPs by darkfield microscopy.	aunps	31-36	erb-b2 receptor tyrosine kinase 2	Homo sapiens	41-46
33766574-1	2021	This paper aimed to systemically investigate the role of adenosine triphosphate-binding cassette (ABC transporters) in the detoxification of non-substrate nanoparticles including titanium dioxide (n-TiO2, 5-10 nm) and gold (AuNPs, 3 nm, 15 nm, and 80 nm, named as Au-3, Au-15 and Au-80) in human lung cancer (A549) and human cervical cancer (HeLa) cells.	aunps	224-229	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	98-101
16815003-1	2007	Based on electrogenerated chemiluminescence (ECL), a novel method for fabrication of alcohol dehydrogenase (ADH) biosensor by self-assembling ADH to Ru(bpy)(3)(2+)-AuNPs aggregates (Ru-AuNPs) on indium tin oxide (ITO) electrode surface has been developed.	aunps	164-169	aldo-keto reductase family 1 member A1	Homo sapiens	85-106
16815003-1	2007	Based on electrogenerated chemiluminescence (ECL), a novel method for fabrication of alcohol dehydrogenase (ADH) biosensor by self-assembling ADH to Ru(bpy)(3)(2+)-AuNPs aggregates (Ru-AuNPs) on indium tin oxide (ITO) electrode surface has been developed.	aunps	164-169	aldo-keto reductase family 1 member A1	Homo sapiens	108-111
16815003-1	2007	Based on electrogenerated chemiluminescence (ECL), a novel method for fabrication of alcohol dehydrogenase (ADH) biosensor by self-assembling ADH to Ru(bpy)(3)(2+)-AuNPs aggregates (Ru-AuNPs) on indium tin oxide (ITO) electrode surface has been developed.	aunps	164-169	aldo-keto reductase family 1 member A1	Homo sapiens	142-145
33232126-14	2020	Iodo-FA and FA-AuNPs both demonstrated excellent concentration-dependent contrast enhancement capabilities (40.5 HU mM-1 and 563.6 HU muM-1, respectively), which were superior to the clinically available agent, iopamidol.	aunps	15-20	PWWP domain containing 3A, DNA repair factor	Homo sapiens	134-139
34560349-7	2022	Based on optimized donor-acceptor pair, a fluorescent turn-on biosensing system is constructed that revealed improved biosensing characteristics compared to Ti3C2-MXene, graphene and AuNPs for the detection of neuron-specific enolase (NSE), including higher sensitivity (~771 mL ng-1), broader linear detection range (0.0001-1500 ng mL-1), better LOD (0.05 pg mL-1), and faster response time (12 min).	aunps	183-188	enolase 2	Homo sapiens	210-233
34224705-6	2021	TEM results show that beta-CD/AuNPs formed were monodispersed and self assembled.	aunps	30-35	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	22-29
34229822-6	2021	AuNPs-dexmedetomidine reduced the neurocognitive effect on anesthetized rats through the regulation of the GSK-3beta signaling pathway.	aunps	0-5	glycogen synthase kinase 3 alpha	Rattus norvegicus	107-116
34087545-4	2021	In this study, through a combination of the advantages exhibited by ordered mesoporous carbon (OMC)@gold nanoparticles (AuNPs) composites and AuPt-methylene blue (AuPt-MB), a disposable ultrasensitive sandwich-configuration electrochemical immunosensor for determination of AFP was designed.	aunps	120-125	alpha fetoprotein	Homo sapiens	274-277
34279016-4	2021	Multiplex sensing is performed by utilizing the distinguishable electrochemical responses of the redox-active species; anthraquinone-2-carboxylic acid (AQ), thionine chloride (TH), and AgNO3 (Ag+) on the PEI-AuNPs conjugates for the detection of MUC1, CA15-3, and HER2, respectively.	aunps	208-213	mucin 1, cell surface associated	Homo sapiens	246-250
34538237-3	2021	RESULTS: RALA/Au nanoparticles were formed by optimising the ratio of RALA to citrate capped AuNPs, with assembly occurring through electrostatic interactions.	aunps	93-98	RAS like proto-oncogene A	Homo sapiens	9-13
34538237-3	2021	RESULTS: RALA/Au nanoparticles were formed by optimising the ratio of RALA to citrate capped AuNPs, with assembly occurring through electrostatic interactions.	aunps	93-98	RAS like proto-oncogene A	Homo sapiens	70-74
34439193-7	2021	In this work, we used AS1411-AuNPs as a carrier for an acridine orange derivative (C8) or Imiquimod (IQ).	aunps	29-34	homeobox C8	Homo sapiens	82-86
34410104-6	2021	The peptide-functionalized nanocomplex showed a higher uptake of AuNPs@MGS in comparison with AuNPs@G or AuNPs@S alone in uPAR-overexpressing cells and exhibits no toxicity when analyzed with MTT assay.	aunps	65-70	plasminogen activator, urokinase receptor	Homo sapiens	122-126
34825014-0	2021	Etching of AuNPs Through Superoxide Radical Dismutation by Cu-Zn Superoxide Dismutase Resulted in Remarkable Changes of its Localized Surface Plasmon Resonance.	aunps	11-16	superoxide dismutase 1	Homo sapiens	59-85
34160212-5	2021	Both in vitro and in vivo experiments demonstrated that such Au-RRVR nanoparticles could be simultaneously induced by furin and acidic pH to form large aggregates within tumorous tissue resulting in improved tumor accumulation and retention, which can further activate the PA and PTT effect of AuNPs for sensitive imaging and efficient therapy of tumors.	aunps	294-299	furin, paired basic amino acid cleaving enzyme	Homo sapiens	118-123
34825014-6	2021	Objectives: In this approach, a colorimetric detection method for SOD activity was developed based on the carboxylic stabilized AuNPs.	aunps	128-133	superoxide dismutase 1	Homo sapiens	66-69
35587543-6	2022	Using linear sweep voltammetry (LSV) and cyclic voltammetry (CV) techniques, PANI- AuNPs- GOX- PPMP/Au electrode exhibited a superior sensing property with a wider linear range of 0.005 to 16.0 mM, and a lower detection limit (LOD) of 0.001 mM compared to PANI-GOx-PPMP/Au Electrode and PANI- GOX- PPMP/AuNPs/Au Electrode.	aunps	303-308	hydroxyacid oxidase 1	Homo sapiens	90-93
35533848-4	2022	The effect of AuNPs on MET release was evaluated using UV-Vis and Laser-Induced Breakdown Spectroscopy (LIBS) techniques.	aunps	14-19	SAFB like transcription modulator	Homo sapiens	23-26
35390524-1	2022	The aim of the study was to investigate in vivo whether the application of immobilized superoxide dismutase (SOD) and catalase (CAT) could enhance DNA repairing systems and reduce level of CPD (cyclobutane pyrimidine dimers) and 6-4PP ((6-4) pyrimidine-pyrimidone photoproducts), and whether the immobilization on gold (AuNPs) and silver (AgNPs) nanoparticeles affects the outcome.	aunps	320-325	catalase	Rattus norvegicus	128-131
35587543-6	2022	Using linear sweep voltammetry (LSV) and cyclic voltammetry (CV) techniques, PANI- AuNPs- GOX- PPMP/Au electrode exhibited a superior sensing property with a wider linear range of 0.005 to 16.0 mM, and a lower detection limit (LOD) of 0.001 mM compared to PANI-GOx-PPMP/Au Electrode and PANI- GOX- PPMP/AuNPs/Au Electrode.	aunps	303-308	hydroxyacid oxidase 1	Homo sapiens	261-264
35587543-6	2022	Using linear sweep voltammetry (LSV) and cyclic voltammetry (CV) techniques, PANI- AuNPs- GOX- PPMP/Au electrode exhibited a superior sensing property with a wider linear range of 0.005 to 16.0 mM, and a lower detection limit (LOD) of 0.001 mM compared to PANI-GOx-PPMP/Au Electrode and PANI- GOX- PPMP/AuNPs/Au Electrode.	aunps	303-308	hydroxyacid oxidase 1	Homo sapiens	293-296
35450327-0	2022	Covalently grafting first-generation PAMAM dendrimers onto MXenes with self-adsorbed AuNPs for use as a functional nanoplatform for highly sensitive electrochemical biosensing of cTnT.	aunps	85-90	troponin T2, cardiac type	Homo sapiens	179-183
35101823-7	2022	Using E. coli O157:H7 as a model target, a good linear relationship is observed between temperature increase and bacteria concentration from 1.00 x 105-1.00 x 109 cfu mL-1 (R2 = 0.9877) with a detection limit of 1.97 x 104 cfu mL-1, which is three orders of magnitude lower than of the MPBA-AuNPs-based colorimetric assays.	aunps	291-296	L1 cell adhesion molecule	Mus musculus	167-171
35098710-3	2022	In this work, two kinds of multifunctionalized hydrogel beads, one consisting of chitosan (CS), Co2+, luminol, and gold nanoparticles (AuNPs) (CS-Co2+-Lu-Au), and another consisting of CS, Co2+, luminol, fluorescein, and AuNPs (CS-Co2+-Lu-FL-Au), were prepared via a facile synthesis method.	aunps	221-226	citrate synthase	Homo sapiens	143-145
34649018-1	2022	A novel surface-enhanced Raman spectroscopy (SERS) method for the determination of nitrofurazone was developed using AuNPs/gamma-Al2O3 nanoparticles protected by beta-cyclodextrin (beta-CD) as substrate prepared in our lab.	aunps	117-122	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	181-188
35063159-5	2022	Additionally, the mechanism of AuNPs@LIG synthesis by laser induction was also investigated, and the deposition potential and the deposition time for the SWASV determination of arsenic were also optimized.	aunps	31-36	ubiquitin conjugating enzyme E2 K	Homo sapiens	37-40
35159742-0	2022	A Novel Highly Sensitive Electrochemical Nitrite Sensor Based on a AuNPs/CS/Ti3C2 Nanocomposite.	aunps	67-72	citrate synthase	Homo sapiens	73-75
35159742-3	2022	In this paper, we prepared an electrochemical sensor for highly sensitive and selective detection of nitrite, based on AuNPs/CS/MXene nanocomposite.	aunps	119-124	citrate synthase	Homo sapiens	125-127
33440266-6	2021	Further experiments demonstrated that AuNPs and LPS augmented the production of cytosolic reactive oxygen species (ROS) in p38 and ERK dependent manner, through upregulating and activating NADPH oxidase 2 (NOX2).	aunps	38-43	mitogen-activated protein kinase 14	Homo sapiens	123-126
33934761-0	2021	Preparation of GO/Fe3O4@PMDA/AuNPs nanocomposite for simultaneous determination of As3+ and Cu2+ by stripping voltammetry.	aunps	29-34	PDS5 cohesin associated factor B	Homo sapiens	83-86
33934761-6	2021	The GCE/GO/Fe3O4@PMDA/AuNPs also has good linearity over a wide concentration range from 5 to 500 ppb for As3+ and 0.5-750 ppb for Cu2+.	aunps	22-27	PDS5 cohesin associated factor B	Homo sapiens	106-109
33609598-12	2021	In addition, treatment with AuNPs significantly restored iNOS and COX-2 levels in Abeta-treated hNSCs.	aunps	28-33	inositol-3-phosphate synthase 1	Homo sapiens	57-61
33609598-12	2021	In addition, treatment with AuNPs significantly restored iNOS and COX-2 levels in Abeta-treated hNSCs.	aunps	28-33	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	66-71
33609598-12	2021	In addition, treatment with AuNPs significantly restored iNOS and COX-2 levels in Abeta-treated hNSCs.	aunps	28-33	amyloid beta precursor protein	Homo sapiens	82-87
33611216-0	2021	A label-free electrochemiluminescence immunosensor for carbohydrate antigen 153 based on polypyrrole-luminol-AuNPs nanocomposites with bi-catalysis.	aunps	109-114	mucin 1, cell surface associated	Homo sapiens	55-79
33611216-7	2021	On this basis, an ECL immunosensor for CA153 was constructed by covalently immobilizing anti-CA153 on PPY-luminol-AuNPs modified indium-doped tin oxide (ITO) electrode.	aunps	114-119	mucin 1, cell surface associated	Homo sapiens	39-44
33611216-7	2021	On this basis, an ECL immunosensor for CA153 was constructed by covalently immobilizing anti-CA153 on PPY-luminol-AuNPs modified indium-doped tin oxide (ITO) electrode.	aunps	114-119	mucin 1, cell surface associated	Homo sapiens	93-98
33422879-2	2021	The sensing strategy involves the weak inner filter effect between AuNPs and N-CDs due to aggregation products of MET with AuNPs.	aunps	67-72	SAFB like transcription modulator	Homo sapiens	114-117
33422879-2	2021	The sensing strategy involves the weak inner filter effect between AuNPs and N-CDs due to aggregation products of MET with AuNPs.	aunps	123-128	SAFB like transcription modulator	Homo sapiens	114-117
33440266-6	2021	Further experiments demonstrated that AuNPs and LPS augmented the production of cytosolic reactive oxygen species (ROS) in p38 and ERK dependent manner, through upregulating and activating NADPH oxidase 2 (NOX2).	aunps	38-43	mitogen-activated protein kinase 1	Homo sapiens	131-134
33440266-6	2021	Further experiments demonstrated that AuNPs and LPS augmented the production of cytosolic reactive oxygen species (ROS) in p38 and ERK dependent manner, through upregulating and activating NADPH oxidase 2 (NOX2).	aunps	38-43	cytochrome b-245 beta chain	Homo sapiens	189-204
33440266-6	2021	Further experiments demonstrated that AuNPs and LPS augmented the production of cytosolic reactive oxygen species (ROS) in p38 and ERK dependent manner, through upregulating and activating NADPH oxidase 2 (NOX2).	aunps	38-43	cytochrome b-245 beta chain	Homo sapiens	206-210
33440266-7	2021	Accordingly, scavenging of ROS or inhibiting the NOX2 dampened NETs release induced by combined AuNPs and LPS treatment.	aunps	96-101	cytochrome b-245 beta chain	Homo sapiens	49-53
33569679-4	2021	AuNPs/Cu-MOF composite was successfully synthesized by amidation reaction between AuNPs functionalized with amino group and Cu-MOFs containing carboxylic acid.	aunps	0-5	lysine acetyltransferase 8	Homo sapiens	9-12
33516376-3	2021	A novel quartz crystal microbalance (QCM) immunoassay method was presented for high sensitivity and selectivity detection of interleukin-6 (IL-6) based on gold nanoparticles functionalized sulfur-doped graphene quantum dot (AuNPs/S-GQD) and hollow ZnS-CdS nanocage (h-ZnS-CdS NC).	aunps	224-229	interleukin 6	Homo sapiens	125-138
33516376-3	2021	A novel quartz crystal microbalance (QCM) immunoassay method was presented for high sensitivity and selectivity detection of interleukin-6 (IL-6) based on gold nanoparticles functionalized sulfur-doped graphene quantum dot (AuNPs/S-GQD) and hollow ZnS-CdS nanocage (h-ZnS-CdS NC).	aunps	224-229	interleukin 6	Homo sapiens	140-144
33076177-2	2021	Herein, a sensitive aptamer-based, sandwich-type surface plasmon enhanced electrochemiluminescence (SPEECL) immunosensor was demonstrated for the detection of cardiac troponin I (cTnI), by means of aptamer conjugated CdS QDs and AuNPs as ECL luminophores and plasmon sources, respectively, in which Tro4 aptamer was used as a capture probe for cTnI and Tro6 aptamer as a detecting probe.	aunps	229-234	troponin I3, cardiac type	Homo sapiens	159-177
33076177-2	2021	Herein, a sensitive aptamer-based, sandwich-type surface plasmon enhanced electrochemiluminescence (SPEECL) immunosensor was demonstrated for the detection of cardiac troponin I (cTnI), by means of aptamer conjugated CdS QDs and AuNPs as ECL luminophores and plasmon sources, respectively, in which Tro4 aptamer was used as a capture probe for cTnI and Tro6 aptamer as a detecting probe.	aunps	229-234	troponin I3, cardiac type	Homo sapiens	179-183
33076177-2	2021	Herein, a sensitive aptamer-based, sandwich-type surface plasmon enhanced electrochemiluminescence (SPEECL) immunosensor was demonstrated for the detection of cardiac troponin I (cTnI), by means of aptamer conjugated CdS QDs and AuNPs as ECL luminophores and plasmon sources, respectively, in which Tro4 aptamer was used as a capture probe for cTnI and Tro6 aptamer as a detecting probe.	aunps	229-234	troponin I3, cardiac type	Homo sapiens	344-348
33076050-4	2021	Meanwhile, g-C3N4 nanosheet loaded with luminol capped AuNPs (Lum-AuNPs@g-C3N4) nanocomposite was used as the ECL signal nanoprobe.	aunps	55-60	lumican	Homo sapiens	62-65
32593845-0	2020	Colorimetric detection of insulin in human serum using GO/AuNPs/TX-100 nanocomposite.	aunps	58-63	insulin	Homo sapiens	26-33
33076071-4	2021	Taking advantage of the localized surface plasmon resonance (LSPR) effect along with good conductivity of AuNPs, the developed AuNP/Ag2S/fluorine-doped tin oxide (FTO) owns much higher photoelectric conversion efficiency, and the photocurrent is 5.3 times that of Ag2S FTO.	aunps	106-111	angiotensin II receptor type 1	Homo sapiens	132-136
32969502-3	2021	For the determination of ACE, thiol modified primary aptamer (Apt1) was selected by using the SELEX method and immobilized on the surface of the poly(5-amino-2-mercapto-1,3,4-thiadiazole (P(AMT)) and AuNPs modified SPE (SPE/P(AMT)/AuNPs) via Au-S bonding.	aunps	200-205	lysophospholipase 1	Homo sapiens	62-66
32256179-12	2020	The increase in the immunoreactivity of IL-6 on day 1 was decreased on day 7 in the spleens of mice treated with 20 nm or 50 nm AuNPs.	aunps	128-133	interleukin 6	Mus musculus	40-44
32493592-2	2020	In this study, we developed a molecular beacon based electrochemical aptasensor to realize the ratiometric signal quantification of VEGF in serum by surface modification of nanocomposites of graphene oxide/methylene blue (GO/MB) and AuNPs followed by the attachment of ferrocene-labeled aptamer (aptamer-Fc) against VEGF.	aunps	233-238	vascular endothelial growth factor A	Homo sapiens	132-136
32790812-5	2020	Verapamil and P-gp antibody competitive experiments, combined with the cellular uptake of AuNPs, indicated that larger NanoDDSs were more conducive to intracellular drug accumulation and thus had improved anticancer activities, due to a size mismatch between the nanoparticles and the active site of P-gp, and, therefore, reduced drug efflux was seen.	aunps	90-95	ATP binding cassette subfamily B member 1	Homo sapiens	300-304
32138930-5	2020	A decreased ECL signal was obtained due to the ECL resonance energy transfer (ECL-RET) effect between the CdS:Mn QDs and AuNPs; meanwhile, MUC1 was sensitively detected with a limit of detection of 0.40 fg mL-1.	aunps	121-126	mucin 1, cell surface associated	Homo sapiens	139-143
32138930-5	2020	A decreased ECL signal was obtained due to the ECL resonance energy transfer (ECL-RET) effect between the CdS:Mn QDs and AuNPs; meanwhile, MUC1 was sensitively detected with a limit of detection of 0.40 fg mL-1.	aunps	121-126	L1 cell adhesion molecule	Mus musculus	206-210
32030384-3	2020	Through specific Cu2+-Abeta-hemin coordination, Abeta directed the assembly of Cu2+-PEI/AuNPs-hemin nanoprobes into network aggregates on a microelectrode interface, which promoted the enrichment of Abeta monomers on the microelectrode.	aunps	88-93	amyloid beta (A4) precursor protein	Mus musculus	22-27
32030384-3	2020	Through specific Cu2+-Abeta-hemin coordination, Abeta directed the assembly of Cu2+-PEI/AuNPs-hemin nanoprobes into network aggregates on a microelectrode interface, which promoted the enrichment of Abeta monomers on the microelectrode.	aunps	88-93	amyloid beta (A4) precursor protein	Mus musculus	48-53
32030384-3	2020	Through specific Cu2+-Abeta-hemin coordination, Abeta directed the assembly of Cu2+-PEI/AuNPs-hemin nanoprobes into network aggregates on a microelectrode interface, which promoted the enrichment of Abeta monomers on the microelectrode.	aunps	88-93	amyloid beta (A4) precursor protein	Mus musculus	48-53
31430735-2	2019	The AuNPs on the surface of the Cu2O nanocrystals not only enhance the electrochemical performance, but also serve as the binding sites for the lactose ligand which can specifically bind with Gal-1.	aunps	4-9	galectin 1	Homo sapiens	192-197