PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
34953047-13	2022	miR-223-3p exhibited its oncogenic role partly by decreasing FBXW7 expression, and consequently promoted the invasion and metastasis of breast cancer cells.	mir-223-3p	0-10	F-box and WD repeat domain containing 7	Homo sapiens	61-66
34979347-12	2022	miR-223-3p negatively regulated Foxo1 to suppress the expression of inflammatory factors.	mir-223-3p	0-10	forkhead box O1	Rattus norvegicus	32-37
33817227-0	2020	MiR-223-3p regulates cell viability, migration, invasion, and apoptosis of non-small cell lung cancer cells by targeting RHOB.	mir-223-3p	0-10	ras homolog family member B	Homo sapiens	121-125
34753389-8	2021	The fibroblast growth factor receptor 2 (FGFR2) was the target of miR-223-3p.	mir-223-3p	66-76	fibroblast growth factor receptor 2	Homo sapiens	4-39
34738867-8	2021	Collectively, we concluded that BMSCs-exo upregulated miR-223-3p to degrade NLRP3 in EPCs, which further reversed the cytotoxic effects of LPS treatment on EPCs to ameliorate LPS-induced AUI.	mir-223-3p	54-64	NLR family, pyrin domain containing 3	Mus musculus	76-81
33522355-6	2021	Luciferase reporter assay was used to detect the binding activity between miR-223-3p and DUXAP8.	mir-223-3p	74-84	double homeobox A pseudogene 8	Homo sapiens	89-95
33522355-11	2021	Moreover, miR-223-3p inhibition or CXCR4 over-expression partly restored the proliferation, migration, and invasion activities of DUXAP8-downregulated PTC cells.	mir-223-3p	10-20	double homeobox A pseudogene 8	Homo sapiens	130-136
34753389-8	2021	The fibroblast growth factor receptor 2 (FGFR2) was the target of miR-223-3p.	mir-223-3p	66-76	fibroblast growth factor receptor 2	Homo sapiens	41-46
34753389-10	2021	Moreover, FGFR2 levels in cells were negatively regulated by miR-223-3p.	mir-223-3p	61-71	fibroblast growth factor receptor 2	Homo sapiens	10-15
34753389-11	2021	Finally, si-FGFR2 significantly reversed the promotion of miR-223-3p inhibitor on cell viability and the inhibition of cell apoptosis.	mir-223-3p	58-68	fibroblast growth factor receptor 2	Homo sapiens	12-17
34713722-12	2021	MiR-223-3p mimic reduced while the miR-223-3p inhibitor increased the expression of GAS5 and P2Y12 in MEG-01 cells.	mir-223-3p	35-45	purinergic receptor P2Y12	Homo sapiens	93-98
34713722-12	2021	MiR-223-3p mimic reduced while the miR-223-3p inhibitor increased the expression of GAS5 and P2Y12 in MEG-01 cells.	mir-223-3p	0-10	purinergic receptor P2Y12	Homo sapiens	93-98
34698362-14	2021	The results from dual luciferase assay confirmed that miR-223-3p was a direct target of KCNQ1OT1.	mir-223-3p	54-64	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	88-96
34237309-11	2021	Overexpression of FOXO3a abated the glycolysis level and alleviated the radioresistance caused by enhancing miR-223-3p to a certain extent.	mir-223-3p	108-118	forkhead box O3	Homo sapiens	18-24
34713722-12	2021	MiR-223-3p mimic reduced while the miR-223-3p inhibitor increased the expression of GAS5 and P2Y12 in MEG-01 cells.	mir-223-3p	35-45	growth arrest specific 5	Homo sapiens	84-88
35020847-8	2022	The stimulatory effect of MIR155HG on human degenerative NP cell pyroptosis was significantly reversed by pretreatment with miR-223-3p mimic or NLRP3 siRNA.	mir-223-3p	124-134	microRNA 155	Homo sapiens	26-32
34150044-7	2021	In SH-SY5Y cells, miR-223-3p can specifically inhibit the HDAC4 expression.	mir-223-3p	18-28	histone deacetylase 4	Homo sapiens	58-63
34199723-7	2021	The miR-223-3p level was significantly related to an increased risk of occurrence of the ischemic EP within 30 days (odds ratio (OR) = 15.74, 95% confidence interval (CI): 2.07-119.93, p = 0.008) and one year (OR = 3.18, 95% CI: 1.40-7.19, p = 0.006), respectively.	mir-223-3p	4-14	epiregulin	Homo sapiens	98-100
34199723-10	2021	Adding miR-223-3p and miR-126-3p to miR-223-3p ratios as predictors into the model calculating the ischemic risk significantly increased the predictive accuracy for combined ischemic EP within one year more than using only clinical ischemic risk parameters.	mir-223-3p	36-46	epiregulin	Homo sapiens	183-185
35608154-0	2022	MiR-223-3p alleviates trigeminal neuropathic pain in the male mouse by targeting MKNK2 and MAPK/ERK signaling.	mir-223-3p	0-10	MAP kinase-interacting serine/threonine kinase 2	Mus musculus	81-86
35608154-0	2022	MiR-223-3p alleviates trigeminal neuropathic pain in the male mouse by targeting MKNK2 and MAPK/ERK signaling.	mir-223-3p	0-10	mitogen-activated protein kinase 1	Mus musculus	96-99
35608154-8	2022	The relationship between miR-223-3p and MKNK2 was tested by a luciferase reporter assay.	mir-223-3p	25-35	MAP kinase-interacting serine/threonine kinase 2	Mus musculus	40-45
35608154-12	2022	Additionally, miR-223-3p overexpression decreased the phosphorylation levels of ERK1/2, JNK, and p38 protein in TGs of CCI-ION mice to inhibit MAPK/ERK signaling.	mir-223-3p	14-24	mitogen-activated protein kinase 3	Mus musculus	80-86
35608154-12	2022	Additionally, miR-223-3p overexpression decreased the phosphorylation levels of ERK1/2, JNK, and p38 protein in TGs of CCI-ION mice to inhibit MAPK/ERK signaling.	mir-223-3p	14-24	mitogen-activated protein kinase 8	Mus musculus	88-91
35608154-12	2022	Additionally, miR-223-3p overexpression decreased the phosphorylation levels of ERK1/2, JNK, and p38 protein in TGs of CCI-ION mice to inhibit MAPK/ERK signaling.	mir-223-3p	14-24	mitogen-activated protein kinase 14	Mus musculus	97-100
35608154-12	2022	Additionally, miR-223-3p overexpression decreased the phosphorylation levels of ERK1/2, JNK, and p38 protein in TGs of CCI-ION mice to inhibit MAPK/ERK signaling.	mir-223-3p	14-24	mitogen-activated protein kinase 1	Mus musculus	148-151
35608154-13	2022	CONCLUSIONS: Overall, miR-223-3p attenuates the development of TN by targeting MKNK2 to suppress MAPK/ERK signaling.	mir-223-3p	22-32	MAP kinase-interacting serine/threonine kinase 2	Mus musculus	79-84
35608154-13	2022	CONCLUSIONS: Overall, miR-223-3p attenuates the development of TN by targeting MKNK2 to suppress MAPK/ERK signaling.	mir-223-3p	22-32	mitogen-activated protein kinase 1	Mus musculus	102-105
35435116-10	2022	We found that both electroacupuncture and miR-223-3p were able to fortify LIF/STAT3 signaling pathway, then the fact of miR-223-3p combination to LIF 3"-UTR sequence was validated via our dual-luciferase assay.	mir-223-3p	42-52	LIF, interleukin 6 family cytokine	Rattus norvegicus	74-77
35435116-10	2022	We found that both electroacupuncture and miR-223-3p were able to fortify LIF/STAT3 signaling pathway, then the fact of miR-223-3p combination to LIF 3"-UTR sequence was validated via our dual-luciferase assay.	mir-223-3p	42-52	signal transducer and activator of transcription 3	Rattus norvegicus	78-83
35435116-10	2022	We found that both electroacupuncture and miR-223-3p were able to fortify LIF/STAT3 signaling pathway, then the fact of miR-223-3p combination to LIF 3"-UTR sequence was validated via our dual-luciferase assay.	mir-223-3p	42-52	LIF, interleukin 6 family cytokine	Rattus norvegicus	146-149
35435116-10	2022	We found that both electroacupuncture and miR-223-3p were able to fortify LIF/STAT3 signaling pathway, then the fact of miR-223-3p combination to LIF 3"-UTR sequence was validated via our dual-luciferase assay.	mir-223-3p	120-130	LIF, interleukin 6 family cytokine	Rattus norvegicus	74-77
35435116-10	2022	We found that both electroacupuncture and miR-223-3p were able to fortify LIF/STAT3 signaling pathway, then the fact of miR-223-3p combination to LIF 3"-UTR sequence was validated via our dual-luciferase assay.	mir-223-3p	120-130	LIF, interleukin 6 family cytokine	Rattus norvegicus	146-149
35229259-0	2022	Sox9 Promotes Cardiomyocyte Apoptosis After Acute Myocardial Infarction by Promoting miR-223-3p and Inhibiting MEF2C.	mir-223-3p	85-95	SRY-box transcription factor 9	Homo sapiens	0-4
35350836-0	2022	miR-223-3p alleviates TGF-beta-induced epithelial-mesenchymal transition and extracellular matrix deposition by targeting SP3 in endometrial epithelial cells.	mir-223-3p	0-10	Sp3 transcription factor	Homo sapiens	122-125
35350836-6	2022	Overexpression of miR-223-3p in EECs was shown to suppress the effects induced by TGF-beta.	mir-223-3p	18-28	transforming growth factor alpha	Homo sapiens	82-90
35350836-10	2022	In conclusion, miR-223-3p alleviates TGF-beta-induced cell migration, invasion, EMT process and ECM deposition in EECs by targeting SP3.	mir-223-3p	15-25	transforming growth factor alpha	Homo sapiens	37-45
35350836-10	2022	In conclusion, miR-223-3p alleviates TGF-beta-induced cell migration, invasion, EMT process and ECM deposition in EECs by targeting SP3.	mir-223-3p	15-25	Sp3 transcription factor	Homo sapiens	132-135
35572884-0	2022	MiR-223-3p affects myocardial inflammation and apoptosis following myocardial infarction via targeting FBXW7.	mir-223-3p	0-10	F-box and WD repeat domain containing 7	Rattus norvegicus	103-108
35572884-6	2022	Overexpression or inhibition of miR-223-3p was conducted in MI model cells in vitro, and the contents of the inflammatory factors tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-10 (IL-10) in cell supernatant were detected by enzyme-linked immunosorbent assay (ELISA).	mir-223-3p	32-42	tumor necrosis factor	Rattus norvegicus	130-157
35572884-6	2022	Overexpression or inhibition of miR-223-3p was conducted in MI model cells in vitro, and the contents of the inflammatory factors tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-10 (IL-10) in cell supernatant were detected by enzyme-linked immunosorbent assay (ELISA).	mir-223-3p	32-42	tumor necrosis factor	Rattus norvegicus	159-168
35572884-6	2022	Overexpression or inhibition of miR-223-3p was conducted in MI model cells in vitro, and the contents of the inflammatory factors tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-10 (IL-10) in cell supernatant were detected by enzyme-linked immunosorbent assay (ELISA).	mir-223-3p	32-42	interleukin 6	Rattus norvegicus	171-184
35572884-6	2022	Overexpression or inhibition of miR-223-3p was conducted in MI model cells in vitro, and the contents of the inflammatory factors tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-10 (IL-10) in cell supernatant were detected by enzyme-linked immunosorbent assay (ELISA).	mir-223-3p	32-42	interleukin 6	Rattus norvegicus	186-190
35572884-6	2022	Overexpression or inhibition of miR-223-3p was conducted in MI model cells in vitro, and the contents of the inflammatory factors tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-10 (IL-10) in cell supernatant were detected by enzyme-linked immunosorbent assay (ELISA).	mir-223-3p	32-42	interleukin 10	Rattus norvegicus	197-211
35572884-6	2022	Overexpression or inhibition of miR-223-3p was conducted in MI model cells in vitro, and the contents of the inflammatory factors tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-10 (IL-10) in cell supernatant were detected by enzyme-linked immunosorbent assay (ELISA).	mir-223-3p	32-42	interleukin 10	Rattus norvegicus	213-218
33999393-0	2021	Anti-apoptotic Effect of MiR-223-3p Suppressing PIK3C2A in Cardiomyocytes from Myocardial Infarction Rat Through Regulating PI3K/Akt Signaling Pathway.	mir-223-3p	25-35	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	Rattus norvegicus	48-55
35111759-10	2021	Further studies found that miR-223-3p lowers the protein levels of PDE4D and inhibiting PDE4D by AAV9-shPDE4D blocks the WHI-induced myocardial injury mediated by miR-223-3p inhibitor.	mir-223-3p	27-37	phosphodiesterase 4D, cAMP specific	Mus musculus	67-72
35111759-10	2021	Further studies found that miR-223-3p lowers the protein levels of PDE4D and inhibiting PDE4D by AAV9-shPDE4D blocks the WHI-induced myocardial injury mediated by miR-223-3p inhibitor.	mir-223-3p	27-37	phosphodiesterase 4D, cAMP specific	Mus musculus	88-93
35111759-10	2021	Further studies found that miR-223-3p lowers the protein levels of PDE4D and inhibiting PDE4D by AAV9-shPDE4D blocks the WHI-induced myocardial injury mediated by miR-223-3p inhibitor.	mir-223-3p	163-173	phosphodiesterase 4D, cAMP specific	Mus musculus	67-72
35111759-10	2021	Further studies found that miR-223-3p lowers the protein levels of PDE4D and inhibiting PDE4D by AAV9-shPDE4D blocks the WHI-induced myocardial injury mediated by miR-223-3p inhibitor.	mir-223-3p	163-173	phosphodiesterase 4D, cAMP specific	Mus musculus	88-93
35111759-11	2021	Conclusion: miR-223-3p ameliorates WHI-induced RIHD through anti-oxidant and anti-programmed cell death mechanisms via activating AMPK by PDE4D regulation.	mir-223-3p	12-22	phosphodiesterase 4D, cAMP specific	Mus musculus	138-143
35202001-0	2022	miR-223-3p inhibits the progression of atherosclerosis via down-regulating the activation of MEK1/ERK1/2 in macrophages.	mir-223-3p	0-10	mitogen-activated protein kinase kinase 1	Homo sapiens	93-97
35202001-0	2022	miR-223-3p inhibits the progression of atherosclerosis via down-regulating the activation of MEK1/ERK1/2 in macrophages.	mir-223-3p	0-10	mitogen-activated protein kinase 3	Homo sapiens	98-104
35202001-11	2022	MiR-223-3p was co-localized with CD68+ macrophages in vulnerable atherosclerotic lesions.	mir-223-3p	0-10	CD68 molecule	Homo sapiens	33-37
35202001-13	2022	The TNF-a immune-positive areas were reduced by miR-223-3p mimics.	mir-223-3p	48-58	tumor necrosis factor	Homo sapiens	4-9
35202001-15	2022	MiR-223-3p mimics reduced the inflammation and the MEK1/ERK1/2 signaling pathway in vivo and in vitro.	mir-223-3p	0-10	mitogen-activated protein kinase kinase 1	Homo sapiens	51-55
35202001-15	2022	MiR-223-3p mimics reduced the inflammation and the MEK1/ERK1/2 signaling pathway in vivo and in vitro.	mir-223-3p	0-10	mitogen-activated protein kinase 3	Homo sapiens	56-62
35202001-16	2022	C16-PAF reversed the effects of miR-223-3p mimics on inflammation and ERK1/2 signaling pathway.	mir-223-3p	32-42	mitogen-activated protein kinase 3	Homo sapiens	70-76
35202001-17	2022	CONCLUSIONS: MiR-223-3p negatively regulates inflammatory responses by the MEK1/ERK1/2 signaling pathway.	mir-223-3p	13-23	mitogen-activated protein kinase kinase 1	Homo sapiens	75-79
35202001-17	2022	CONCLUSIONS: MiR-223-3p negatively regulates inflammatory responses by the MEK1/ERK1/2 signaling pathway.	mir-223-3p	13-23	mitogen-activated protein kinase 3	Homo sapiens	80-86
35194762-0	2022	Notch activation suppresses endothelial cell migration and sprouting via miR-223-3p targeting Fbxw7.	mir-223-3p	73-83	F-box and WD repeat domain containing 7	Homo sapiens	94-99
35194762-10	2022	In summary, these results identify that Notch activation-induced miR-223-3p suppresses EC migration and sprouting via Fbxw7.	mir-223-3p	65-75	F-box and WD repeat domain containing 7	Homo sapiens	118-123
34387610-12	2022	Moreover, miR-223-3p increased bortezomib sensitivity by inhibiting BRD4.	mir-223-3p	10-20	bromodomain containing 4	Homo sapiens	68-72
33839256-7	2021	Under TGF-beta stimulation, the overexpression of miR-223-3p enhanced, whereas the inhibition of miR-223-3p inhibited the EMT and MAPK signaling pathways.	mir-223-3p	50-60	transforming growth factor alpha	Homo sapiens	6-14
33839256-7	2021	Under TGF-beta stimulation, the overexpression of miR-223-3p enhanced, whereas the inhibition of miR-223-3p inhibited the EMT and MAPK signaling pathways.	mir-223-3p	97-107	transforming growth factor alpha	Homo sapiens	6-14
33986876-9	2021	miR-223-3p promoted cell proliferation, migration, invasion and EMT, and the western blotting results demonstrated that miR-223-3p inhibition increased the phosphorylation of Yap1 and the protein expression levels of large tumor suppressor kinase 1.	mir-223-3p	0-10	Yes1 associated transcriptional regulator	Homo sapiens	175-179
33986876-9	2021	miR-223-3p promoted cell proliferation, migration, invasion and EMT, and the western blotting results demonstrated that miR-223-3p inhibition increased the phosphorylation of Yap1 and the protein expression levels of large tumor suppressor kinase 1.	mir-223-3p	0-10	large tumor suppressor kinase 1	Homo sapiens	217-248
33986876-9	2021	miR-223-3p promoted cell proliferation, migration, invasion and EMT, and the western blotting results demonstrated that miR-223-3p inhibition increased the phosphorylation of Yap1 and the protein expression levels of large tumor suppressor kinase 1.	mir-223-3p	120-130	Yes1 associated transcriptional regulator	Homo sapiens	175-179
33986876-9	2021	miR-223-3p promoted cell proliferation, migration, invasion and EMT, and the western blotting results demonstrated that miR-223-3p inhibition increased the phosphorylation of Yap1 and the protein expression levels of large tumor suppressor kinase 1.	mir-223-3p	120-130	large tumor suppressor kinase 1	Homo sapiens	217-248
33986876-10	2021	In conclusion, results from the present results suggested that miR-223-3p may promote cell proliferation, migration, invasion and EMT through the Hippo/Yap signaling pathway.	mir-223-3p	63-73	Yes1 associated transcriptional regulator	Homo sapiens	152-155
33608866-0	2021	MiR-223-3p inhibits inflammation and pyroptosis in monosodium urate-induced rats and fibroblast-like synoviocytes by targeting NLRP3.	mir-223-3p	0-10	NLR family, pyrin domain containing 3	Rattus norvegicus	127-132
33608866-14	2021	MiR-223-3p inhibited pyroptosis in MSU-induced rats and FLSs by targeting NLRP3.	mir-223-3p	0-10	NLR family, pyrin domain containing 3	Rattus norvegicus	74-79
33999393-0	2021	Anti-apoptotic Effect of MiR-223-3p Suppressing PIK3C2A in Cardiomyocytes from Myocardial Infarction Rat Through Regulating PI3K/Akt Signaling Pathway.	mir-223-3p	25-35	AKT serine/threonine kinase 1	Rattus norvegicus	129-132
33999393-11	2021	Low expression of miR-223-3p may downregulate PIK3C2A expression, resulting in the inhibition of myocardial cell apoptosis in rats with myocardial infarction via the activation of PI3K/Akt signaling pathway.	mir-223-3p	18-28	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha	Rattus norvegicus	46-53
33999393-11	2021	Low expression of miR-223-3p may downregulate PIK3C2A expression, resulting in the inhibition of myocardial cell apoptosis in rats with myocardial infarction via the activation of PI3K/Akt signaling pathway.	mir-223-3p	18-28	AKT serine/threonine kinase 1	Rattus norvegicus	185-188
33744257-12	2021	Inhibition of miR-223-3p could abate the function of KCNQ1OT1 silence in H2O2-treated SRA01/04 cells.	mir-223-3p	14-24	KCNQ1 opposite strand/antisense transcript 1	Homo sapiens	53-61
33647318-9	2021	In contrast, overexpression of STAT3 diminished the effect of miR-223-3p.	mir-223-3p	62-72	signal transducer and activator of transcription 3	Mus musculus	31-36
33647318-10	2021	Taken together, the results indicate a protective role of miR-223-3p that inhibits both medial and atherosclerotic vascular calcification by regulating IL-6/STAT3 signaling mediated VSMC transdifferentiation.	mir-223-3p	58-68	interleukin 6	Mus musculus	152-156
33647318-10	2021	Taken together, the results indicate a protective role of miR-223-3p that inhibits both medial and atherosclerotic vascular calcification by regulating IL-6/STAT3 signaling mediated VSMC transdifferentiation.	mir-223-3p	58-68	signal transducer and activator of transcription 3	Mus musculus	157-162
33574820-7	2020	The transfection with miR-223-3p mimic significantly suppressed a luciferase activity in HUVEC treated with a Lentivirus vector containing 3" UTR of S1pr1.	mir-223-3p	22-32	sphingosine-1-phosphate receptor 1	Mus musculus	149-154
32522014-9	2021	Dual-luciferase reporter assay was constructed to validate the interaction between miR-223-3p and circABCB10 or PFN2.	mir-223-3p	83-93	profilin 2	Homo sapiens	112-116
33310596-0	2021	CircLRRK1 targets miR-223-3p to inhibit the proliferation, migration and invasion of trophoblast cells by regulating the PI3K/AKT signaling pathway.	mir-223-3p	18-28	AKT serine/threonine kinase 1	Homo sapiens	126-129
32926880-7	2020	Secondly, through in vitro experiments, we found that inhibition of GAS5 with elevated expression of miR-223-3p decreased the proliferative capacity of cardiomyocytes and increased apoptotic capacity and inflammatory factors (P < 0.050).	mir-223-3p	101-111	growth arrest specific 5	Homo sapiens	68-72
32765674-0	2020	miR-223-3p reduces high glucose and high fat-induced endothelial cell injury in diabetic mice by regulating NLRP3 expression.	mir-223-3p	0-10	NLR family, pyrin domain containing 3	Mus musculus	108-113
32765674-6	2020	Flow cytometry was used to observe apoptosis and TargetScan to predict the target relationship between miR-223-3p and NLRP3.	mir-223-3p	103-113	NLR family, pyrin domain containing 3	Mus musculus	118-123
32765674-7	2020	Dual-luciferase reporter gene assay was used to detect the relationship between miR-223-3p and NLRP3.	mir-223-3p	80-90	NLR family, pyrin domain containing 3	Mus musculus	95-100
32765674-12	2020	miR-223-3p reduces the injury of MCMECs and inhibits endothelial cell apoptosis in mice by regulating the expression of NLRP3.	mir-223-3p	0-10	NLR family, pyrin domain containing 3	Mus musculus	120-125
32615662-0	2020	Increased miR-223-3p in Leukocytes Positively Correlated with IL-17A in Plasma of Asthmatic Patients.	mir-223-3p	10-20	interleukin 17A	Homo sapiens	62-68
33145937-0	2020	MiR-223-3p inhibits rTp17-induced inflammasome activation and pyroptosis by targeting NLRP3.	mir-223-3p	0-10	NLR family pyrin domain containing 3	Homo sapiens	86-91
33145937-6	2020	The biological function of miR-223-3p in the NLRP3 inflammasome and pyroptosis was evaluated in T pallidum-infected human umbilical vein endothelial cells (HUVECs).	mir-223-3p	27-37	NLR family pyrin domain containing 3	Homo sapiens	45-50
33145937-8	2020	Moreover, miR-223-3p showed a notable inhibitory effect on recombinant Tp17 (rTP17)-induced caspase-1 activation, resulting in decrease in IL-1beta production and pyroptosis, which was accompanied by the release of lactate dehydrogenase (LDH) in HUVECs.	mir-223-3p	10-20	caspase 1	Homo sapiens	92-101
33145937-8	2020	Moreover, miR-223-3p showed a notable inhibitory effect on recombinant Tp17 (rTP17)-induced caspase-1 activation, resulting in decrease in IL-1beta production and pyroptosis, which was accompanied by the release of lactate dehydrogenase (LDH) in HUVECs.	mir-223-3p	10-20	interleukin 1 alpha	Homo sapiens	139-147
33145937-10	2020	Moreover, NLRP3 overexpression or knockdown largely blocked the effects of miR-223-3p on T pallidum-induced inflammasome activation and pyroptosis in HUVECs.	mir-223-3p	75-85	NLR family pyrin domain containing 3	Homo sapiens	10-15
32838617-4	2021	Thrombin/fibrinogen-induced exosome and microvesicle generation was inhibited by miR-223-3p transfection, and this effect was reversed with a RISC inhibitor.	mir-223-3p	81-91	coagulation factor II, thrombin	Homo sapiens	0-8
32838617-4	2021	Thrombin/fibrinogen-induced exosome and microvesicle generation was inhibited by miR-223-3p transfection, and this effect was reversed with a RISC inhibitor.	mir-223-3p	81-91	fibrinogen beta chain	Homo sapiens	9-19
32493731-6	2020	Mechanistically, we found that myeloid-derived miR-223-3p suppresses the target gene interleukin-6 (Il6), associated with the maintenance of the proinflammatory macrophage phenotype during injury.	mir-223-3p	47-57	interleukin 6	Mus musculus	85-98
32493731-6	2020	Mechanistically, we found that myeloid-derived miR-223-3p suppresses the target gene interleukin-6 (Il6), associated with the maintenance of the proinflammatory macrophage phenotype during injury.	mir-223-3p	47-57	interleukin 6	Mus musculus	100-103
32656268-0	2020	miR-223-3p Inhibits Antigen Endocytosis and Presentation and Promotes the Tolerogenic Potential of Dendritic Cells through Targeting Mannose Receptor Signaling and Rhob.	mir-223-3p	0-10	mannose receptor C-type 1	Homo sapiens	133-149
32656268-0	2020	miR-223-3p Inhibits Antigen Endocytosis and Presentation and Promotes the Tolerogenic Potential of Dendritic Cells through Targeting Mannose Receptor Signaling and Rhob.	mir-223-3p	0-10	ras homolog family member B	Homo sapiens	164-168
32656268-9	2020	The miR-223-3p mimic increased TGF-beta1 production in OVA-treated DCs (P < 0.01).	mir-223-3p	4-14	transforming growth factor beta 1	Homo sapiens	31-40
32656268-11	2020	In addition, the miR-223-3p mimic significantly upregulated CD103 in DCs, indicating the promotion of tolerogenic DCs.	mir-223-3p	17-27	integrin subunit alpha E	Homo sapiens	60-65
32656268-12	2020	The miR-223-3p mimic downregulated Rhob protein in OVA-induced DCs.	mir-223-3p	4-14	ras homolog family member B	Homo sapiens	35-39
32656268-15	2020	Conclusion: These data suggest that miR-223-3p has an inhibitory effect on the antigen uptake and presentation capacities of BMDCs and promotes Treg cell differentiation, which is, at least partially, through targeting MR signaling and Rhob.	mir-223-3p	36-46	ras homolog family member B	Homo sapiens	236-240
30821011-9	2019	Moreover, the activated RIP3 reversed the inhibition of RIP3 and MLKL expression and the levels of TNF-alpha, IL-1beta, and lactate dehydrogenase, which were induced by transfection with miR-223-3p in a H 2 O 2 -induced model.	mir-223-3p	187-197	receptor interacting serine/threonine kinase 3	Homo sapiens	24-28
32478689-15	2020	On the other hand, miR-223-3p functioned in AF by targeting PAX6, which was associated with the regulation of apoptosis in AF.	mir-223-3p	19-29	paired box 6	Homo sapiens	60-64
31696486-0	2019	MiR-223-3p promotes the growth and invasion of neuroblastoma cell via targeting FOXO1.	mir-223-3p	0-10	forkhead box O1	Homo sapiens	80-85
31696486-8	2019	MiR-223-3p was able to bind with the 3"-untranslated region of FOXO1, and thereby resulting in a reduction of FOXO1 expression.	mir-223-3p	0-10	forkhead box O1	Homo sapiens	63-68
31696486-8	2019	MiR-223-3p was able to bind with the 3"-untranslated region of FOXO1, and thereby resulting in a reduction of FOXO1 expression.	mir-223-3p	0-10	forkhead box O1	Homo sapiens	110-115
31486492-0	2019	MiR-223-3p inhibits proliferation and metastasis of oral squamous cell carcinoma by targeting SHOX2.	mir-223-3p	0-10	short stature homeobox 2	Homo sapiens	94-99
31486492-10	2019	CONCLUSIONS: MiR-223-3p acted as a tumor suppressor gene in OSCC by targeting SHOX2.	mir-223-3p	13-23	short stature homeobox 2	Homo sapiens	78-83
30821011-9	2019	Moreover, the activated RIP3 reversed the inhibition of RIP3 and MLKL expression and the levels of TNF-alpha, IL-1beta, and lactate dehydrogenase, which were induced by transfection with miR-223-3p in a H 2 O 2 -induced model.	mir-223-3p	187-197	receptor interacting serine/threonine kinase 3	Homo sapiens	56-60
30821011-9	2019	Moreover, the activated RIP3 reversed the inhibition of RIP3 and MLKL expression and the levels of TNF-alpha, IL-1beta, and lactate dehydrogenase, which were induced by transfection with miR-223-3p in a H 2 O 2 -induced model.	mir-223-3p	187-197	mixed lineage kinase domain like pseudokinase	Homo sapiens	65-69
30821011-9	2019	Moreover, the activated RIP3 reversed the inhibition of RIP3 and MLKL expression and the levels of TNF-alpha, IL-1beta, and lactate dehydrogenase, which were induced by transfection with miR-223-3p in a H 2 O 2 -induced model.	mir-223-3p	187-197	tumor necrosis factor	Homo sapiens	99-108
30821011-9	2019	Moreover, the activated RIP3 reversed the inhibition of RIP3 and MLKL expression and the levels of TNF-alpha, IL-1beta, and lactate dehydrogenase, which were induced by transfection with miR-223-3p in a H 2 O 2 -induced model.	mir-223-3p	187-197	interleukin 1 beta	Homo sapiens	110-118
30668544-0	2019	MiR-223-3p promotes cell proliferation and metastasis by downregulating SLC4A4 in clear cell renal cell carcinoma.	mir-223-3p	0-10	solute carrier family 4 member 4	Homo sapiens	72-78
30668544-9	2019	Given that miR-223-3p suppressed the SLC4A4/KRAS axis, miR-223-3p gene therapy could be an effective treatment for renal cancer.	mir-223-3p	11-21	solute carrier family 4 member 4	Homo sapiens	37-43
30668544-9	2019	Given that miR-223-3p suppressed the SLC4A4/KRAS axis, miR-223-3p gene therapy could be an effective treatment for renal cancer.	mir-223-3p	11-21	KRAS proto-oncogene, GTPase	Homo sapiens	44-48
30668544-9	2019	Given that miR-223-3p suppressed the SLC4A4/KRAS axis, miR-223-3p gene therapy could be an effective treatment for renal cancer.	mir-223-3p	55-65	solute carrier family 4 member 4	Homo sapiens	37-43
30668544-9	2019	Given that miR-223-3p suppressed the SLC4A4/KRAS axis, miR-223-3p gene therapy could be an effective treatment for renal cancer.	mir-223-3p	55-65	KRAS proto-oncogene, GTPase	Homo sapiens	44-48
31450504-5	2019	In vitro, miR-223-3p suppressed the translation of IGF1R in neural cells.	mir-223-3p	10-20	insulin-like growth factor 1 receptor	Rattus norvegicus	51-56