PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 26905725-3 2016 Arabidopsis spermine (Spm) synthase (SPMS) gene-deficient mutant was previously shown to be rather resistant to the diamine cadaverine (Cad). Cadaverine 124-134 spermidine synthase 3 Arabidopsis thaliana 37-41 26905725-3 2016 Arabidopsis spermine (Spm) synthase (SPMS) gene-deficient mutant was previously shown to be rather resistant to the diamine cadaverine (Cad). Cadaverine 136-139 spermidine synthase 3 Arabidopsis thaliana 37-41 23811823-7 2013 The accumulation of 2-piperidone in the Cyp2e1-null mice was mainly caused by the changes in the biosynthesis and degradation of 2-piperidone because compared with the WT mice, the conversion of cadaverine to 2-piperidone was higher, whereas the metabolism of 2-piperidone to 6-hydroxy-2-piperidone was lower in the Cyp2e1-null mice. Cadaverine 195-205 cytochrome P450, family 2, subfamily e, polypeptide 1 Mus musculus 40-46 24218586-7 2013 The large majority of neurons activated by low concentrations of cadaverine expresses a particular olfactory receptor, trace amine-associated receptor 13c (TAAR13c). Cadaverine 65-75 trace amine associated receptor 13c Danio rerio 119-154 24218586-7 2013 The large majority of neurons activated by low concentrations of cadaverine expresses a particular olfactory receptor, trace amine-associated receptor 13c (TAAR13c). Cadaverine 65-75 trace amine associated receptor 13c Danio rerio 156-163 25938752-3 2015 The vaginal DA (VADA) assay is based on the enzyme diamine oxidase which reacts with putrescine and cadaverine to produce H2O2 in a quantitative manner. Cadaverine 100-110 amine oxidase copper containing 1 Homo sapiens 51-66 25403917-0 2015 Natural variation in the expression of ORGANIC CATION TRANSPORTER 1 affects root length responses to cadaverine in Arabidopsis. Cadaverine 101-111 organic cation/carnitine transporter1 Arabidopsis thaliana 39-67 25403917-6 2015 OCT1 expression was higher in Cvi than in Ler, and oct1 mutants were more sensitive to cadaverine than wild-type plants. Cadaverine 87-97 organic cation/carnitine transporter1 Arabidopsis thaliana 51-55 25403917-7 2015 In oct1 mutants transformed with an ectopic copy of OCT1 originating from either Cvi or Ler, the expression level of the transgene, not its accession, correlated with the cadaverine response. Cadaverine 171-181 organic cation/carnitine transporter1 Arabidopsis thaliana 3-7 25403917-7 2015 In oct1 mutants transformed with an ectopic copy of OCT1 originating from either Cvi or Ler, the expression level of the transgene, not its accession, correlated with the cadaverine response. Cadaverine 171-181 organic cation/carnitine transporter1 Arabidopsis thaliana 52-56 25403917-8 2015 These results suggest that decreased OCT1 expression confers cadaverine sensitivity in some accessions. Cadaverine 61-71 organic cation/carnitine transporter1 Arabidopsis thaliana 37-41 23811823-7 2013 The accumulation of 2-piperidone in the Cyp2e1-null mice was mainly caused by the changes in the biosynthesis and degradation of 2-piperidone because compared with the WT mice, the conversion of cadaverine to 2-piperidone was higher, whereas the metabolism of 2-piperidone to 6-hydroxy-2-piperidone was lower in the Cyp2e1-null mice. Cadaverine 195-205 cytochrome P450, family 2, subfamily e, polypeptide 1 Mus musculus 316-322 23327914-7 2012 RESULTS: (1) The serum contents of TNF-alpha, IL-1, and IL-6 were increased in NTH, putrescine, and cadaverine groups in different degrees at most post injection time points. Cadaverine 100-110 tumor necrosis factor Oryctolagus cuniculus 35-44 23327914-15 2012 The obvious correlation between cadaverine group and NTH group was only found in the contents of IL-1 and IL-6 (r(IL-1) = 0.913, P < 0.01; r(IL-6) = 0.883, P < 0.05). Cadaverine 32-42 interleukin-6 Oryctolagus cuniculus 106-110 23327914-15 2012 The obvious correlation between cadaverine group and NTH group was only found in the contents of IL-1 and IL-6 (r(IL-1) = 0.913, P < 0.01; r(IL-6) = 0.883, P < 0.05). Cadaverine 32-42 interleukin-6 Oryctolagus cuniculus 144-148 23539494-3 2013 In the presence of Brij 76 (1.5 %), Hg(2+) (7.5 muM), and cadaverine (10 muM) at pH 5.0, this SALDI-MS approach allowed the simultaneous detection of T15, T20, T33, and T40, with limits of detection at the femtomole-to-picomole level and sample-to-sample intensity variation <23 %. Cadaverine 58-68 latexin Homo sapiens 73-76 23539494-4 2013 In the presence of Ag(+) (1 muM) and cadaverine (10 muM) at pH 7.0, this technique allowed the detection of randomly sequenced ss- and ds-ODNs at concentrations down to the femtomole level. Cadaverine 37-47 latexin Homo sapiens 52-55 29403792-7 2013 The cadaverine, putrescine and 1, 3-diaminopropane levels were significantly higher in U14 model mice plasma than those in normal mice plasma, especially the putrescine and 1, 3-diaminopropane (P<0.01). Cadaverine 4-14 small nucleolar RNA, C/D box 14C Mus musculus 87-90 29403792-8 2013 The cadaverine, putrescine and 1, 3-diaminopropane levels were significantly higher in U14 mice model urine than those in normal mice urine, especially the cadaverine and 1, 3-diaminopropane (P<0.01). Cadaverine 4-14 small nucleolar RNA, C/D box 14C Mus musculus 87-90 29403792-8 2013 The cadaverine, putrescine and 1, 3-diaminopropane levels were significantly higher in U14 mice model urine than those in normal mice urine, especially the cadaverine and 1, 3-diaminopropane (P<0.01). Cadaverine 156-166 small nucleolar RNA, C/D box 14C Mus musculus 87-90 23327914-7 2012 RESULTS: (1) The serum contents of TNF-alpha, IL-1, and IL-6 were increased in NTH, putrescine, and cadaverine groups in different degrees at most post injection time points. Cadaverine 100-110 interleukin-6 Oryctolagus cuniculus 56-60 18389226-0 2008 CE-LIF determination of salivary cadaverine and lysine concentration ratio as an indicator of lysine decarboxylase enzyme activity. Cadaverine 33-43 LIF interleukin 6 family cytokine Homo sapiens 3-6 22328822-7 2012 RESULTS: All of the haplotype variants of LOXL1 (141R-153G, 141R-153D, 141L-153G, and 141L-153D) showed beta-aminopropionitrile-inhibitable amine oxidase activity toward elastin, type I collagen, and cadaverine, indicating that each LOXL1 variant functions as an amine oxidase. Cadaverine 200-210 lysyl oxidase like 1 Homo sapiens 42-47 20855735-8 2010 By measuring cadaverine production, we discovered that the PA4115 mutant had significantly reduced lysine decarboxylase activity. Cadaverine 13-23 hypothetical protein Pseudomonas aeruginosa PAO1 59-65 20855735-10 2010 Cadaverine increased the rate of killing and lysis of the PA4115 mutant in the presence of both antibiotics. Cadaverine 0-10 hypothetical protein Pseudomonas aeruginosa PAO1 58-64 20167857-4 2010 However, cadaverine, the most widely used substrate for TGase activity assay, is not isozyme specific. Cadaverine 9-19 transglutaminase 1 Homo sapiens 56-61 19627092-3 2009 Two examples of enzymatic reactions were investigated: the hydrolysis of arginine to ornithine catalyzed by arginase and the oxidation of cadaverine to 5-aminopentanal by diamine oxidase, in which the substrates have a higher affinity to the macrocycle than the products ("substrate-selective assays"). Cadaverine 138-148 amine oxidase copper containing 1 Homo sapiens 171-186 19627092-9 2009 Through the sequential coupling of a "product-selective" with a "substrate-selective" assay it was furthermore possible to monitor a multistep biochemical pathway, namely the decarboxylation of lysine to cadaverine by lysine decarboxylase followed by the oxidation of cadaverine by diamine oxidase. Cadaverine 204-214 amine oxidase copper containing 1 Homo sapiens 282-297 20439985-1 2010 In this report, we assessed the steady-state enzymatic activity of lysyl oxidase-like 2 (LOXL2) against the substrates 1,5-diaminopentane (DAP), spermine, and fibrillar type I collagen. Cadaverine 119-137 lysyl oxidase like 2 Homo sapiens 67-87 20439985-1 2010 In this report, we assessed the steady-state enzymatic activity of lysyl oxidase-like 2 (LOXL2) against the substrates 1,5-diaminopentane (DAP), spermine, and fibrillar type I collagen. Cadaverine 119-137 lysyl oxidase like 2 Homo sapiens 89-94 20439985-1 2010 In this report, we assessed the steady-state enzymatic activity of lysyl oxidase-like 2 (LOXL2) against the substrates 1,5-diaminopentane (DAP), spermine, and fibrillar type I collagen. Cadaverine 139-142 lysyl oxidase like 2 Homo sapiens 67-87 20439985-1 2010 In this report, we assessed the steady-state enzymatic activity of lysyl oxidase-like 2 (LOXL2) against the substrates 1,5-diaminopentane (DAP), spermine, and fibrillar type I collagen. Cadaverine 139-142 lysyl oxidase like 2 Homo sapiens 89-94 20439985-2 2010 We find that both DAP and spermine are capable of activating LOXL2 to the same extent and have similar Michaelis constants (K(m) approximately 1 mm) and catalytic rates (k(cat) approximately 0.02 s(-1)). Cadaverine 18-21 lysyl oxidase like 2 Homo sapiens 61-66 20439985-5 2010 In addition, we identified an antibody inhibitor (AB0023) of LOXL2 enzymatic function and have found that the inhibition occurs in a non-competitive manner with respect to both spermine and DAP. Cadaverine 190-193 lysyl oxidase like 2 Homo sapiens 61-66 19821519-7 2010 The porin inhibitor cadaverine was added to study the porin-mediated influx of toluene. Cadaverine 20-30 porin Pseudomonas putida 4-9 17826755-3 2007 DESIGN AND METHODS: DAO activity was measured by using cadaverine coupled to O-dianisidine oxidation in 50 healthy individuals. Cadaverine 55-65 amine oxidase copper containing 1 Homo sapiens 20-23 11942921-5 2002 To relate the effects of polylysine on contractility in smooth muscle to physiologically relevant material, we investigated the ability of naturally occurring positively charged polyamines, histones, cadaverine, putrescine and spermidine to activate the Mg2+ ATPase activity of unphosphorylated smooth muscle myosin. Cadaverine 200-210 mucin 7, secreted Homo sapiens 254-257 16936095-8 2006 tTgase activity was assayed by incorporation of biotinylated cadaverine into fibronectin. Cadaverine 61-71 transglutaminase 2 Homo sapiens 0-6 16936095-8 2006 tTgase activity was assayed by incorporation of biotinylated cadaverine into fibronectin. Cadaverine 61-71 fibronectin 1 Homo sapiens 77-88 14570723-4 2003 The inhibitory capacity of the antibodies on tTG activity was checked by a fluorometric assay based on the incorporation of monodansyl cadaverine into casein and by tTG-catalysed cross linking of biotinylated cadaverine to gliadin. Cadaverine 135-145 transglutaminase 2 Homo sapiens 45-48 18251895-8 2007 A biotin-labeled cadaverine incorporation assay showed that TGase activity occurred in S1 (containing soluble proteins), S2 (proteins released by both cell walls and membranes) and S3 (membrane intrinsic proteins) fractions. Cadaverine 17-27 transglutaminase 1 Homo sapiens 60-65 15972954-6 2005 TSP-2-null mice had reduced tTG activity in skin, as measured by incorporation of fluorescein isothiocyanate-labeled cadaverine, and a threefold increase in acetic acid-extracted dermal collagen. Cadaverine 117-127 tumor suppressor region 2 Mus musculus 0-5 15138821-7 2004 Both a colorimetric and a radiometric assay for TGase activity, the former carried out in the presence of biotinylated cadaverine and the latter in the presence of polyamines labelled with radioactive isotopes and resulting in the isolation of glutamyl-polyamines, further confirmed that the thylakoid enzyme is indeed a calcium-dependent transglutaminase (Thyl-TGase). Cadaverine 119-129 transglutaminase15 Zea mays 48-53 15221502-12 2004 This function of diamine oxidase is to be considered as part of a general defence function, of which the prevention of histamine and cadaverine accumulation from the gastrointestinal tract is a well-known aspect. Cadaverine 133-143 amine oxidase copper containing 1 Homo sapiens 17-32 18494907-9 2003 Labelled cadaverine as an exogenous substrate for transglutaminase (TGase) could be incorporated into CEs during maturation. Cadaverine 9-19 transglutaminase 1 Homo sapiens 50-66 18494907-9 2003 Labelled cadaverine as an exogenous substrate for transglutaminase (TGase) could be incorporated into CEs during maturation. Cadaverine 9-19 transglutaminase 1 Homo sapiens 68-73 14755941-1 2003 Our study showed that the administration in pre-treatment of some polyamines (especially spermine and spermidine and almost null agmatine, putrescine and cadaverine) reduced the contractile effects of angiotensin II (Ang II) in isolated rat aorta. Cadaverine 154-164 angiotensinogen Rattus norvegicus 201-215 14755941-1 2003 Our study showed that the administration in pre-treatment of some polyamines (especially spermine and spermidine and almost null agmatine, putrescine and cadaverine) reduced the contractile effects of angiotensin II (Ang II) in isolated rat aorta. Cadaverine 154-164 angiotensinogen Rattus norvegicus 217-223 11485548-5 2001 Founder lines with >1000-fold overexpression of ODC in the heart were established, resulting in a 50-fold overaccumulation of putrescine, 4-fold elevation in spermidine, a slight increase in spermine and accumulation of large amounts of cadaverine compared with littermate controls. Cadaverine 240-250 ornithine decarboxylase, structural 1 Mus musculus 51-54 10379569-4 1999 DAO is the enzyme which catalyzes the oxidation of agmatine, cadaverine, and putrescine with the production of NH and H2O2. Cadaverine 61-71 D-amino acid oxidase Bos taurus 0-3 10892867-6 2000 External tTgase activity was measured by the ability to form polymerized fibronectin and the incorporation of biotinylated cadaverine into fibronectin. Cadaverine 123-133 transglutaminase 2 Homo sapiens 9-15 10892867-11 2000 Incorporation of biotinylated cadaverine was markedly increased when HTM cells were treated with TGF-beta for 24 hours before seeding. Cadaverine 30-40 transforming growth factor beta 1 Homo sapiens 97-105 11040105-3 2000 In ODC transgenic hearts, putrescine and cadaverine levels were highly elevated ( identical with 35-fold for putrescine), spermidine was increased 3.6-fold, but spermine was essentially unchanged. Cadaverine 41-51 ornithine decarboxylase, structural 1 Mus musculus 3-6 7625228-2 1995 In the present study the activity of plasmatic histaminase was analysed, with histamine and with cadaverine as substrates, in a group of 23 schizophrenic patients and compared with that of healthy controls (n = 32). Cadaverine 97-107 amine oxidase copper containing 1 Homo sapiens 47-58 9410884-7 1997 A novel assay was developed to measure externalised tTgase activity which is cell mediated, inhibited by preincubation of cells with anti-tTgase antibody and relies on the incorporation of biotinylated cadaverine into fibronectin. Cadaverine 202-212 fibronectin 1 Homo sapiens 218-229 7625228-4 1995 On the other hand, when cadaverine was used as substrate plasma histaminase was significantly reduced in female schizophrenics but not in males. Cadaverine 24-34 amine oxidase copper containing 1 Homo sapiens 64-75 7823945-4 1995 Exogeneous expression of c-myb in transfected cell lines abrogated erythroid differentiation induced by cadaverine or cytosine arabinoside as assessed by hemoglobin production. Cadaverine 104-114 MYB proto-oncogene, transcription factor Homo sapiens 25-30 8125959-9 1994 alpha-Difluoromethylornithine, a selective inhibitor of ornithine decarboxylase, inhibited both cadaverine and putrescine export. Cadaverine 96-106 ornithine decarboxylase 1 Homo sapiens 56-79 8125959-11 1994 The cumulative data suggested that cadaverine formation may be caused by the action of intracellular ornithine decarboxylase upon lysine to produce cadaverine, which is then effluxed from the cell with a high degree of efficiency. Cadaverine 35-45 ornithine decarboxylase 1 Homo sapiens 101-124 8125959-11 1994 The cumulative data suggested that cadaverine formation may be caused by the action of intracellular ornithine decarboxylase upon lysine to produce cadaverine, which is then effluxed from the cell with a high degree of efficiency. Cadaverine 148-158 ornithine decarboxylase 1 Homo sapiens 101-124 1458548-3 1992 The observed partitioning ratios go through a minimum value with 1,5-diaminopentane, the best substrate of diamine oxidase of the compounds tested. Cadaverine 65-83 amine oxidase copper containing 1 Homo sapiens 107-122 7517727-3 1994 With this method and diamine substrates cadaverine or putrescine, or polyamine substrates spermidine or spermine as substrates, DAOX was localized species-independently but substrate-dependently in the basolateral cytoplasm and/or plasma membrane of small intestinal enterocytes of rats, mice and gerbils. Cadaverine 40-50 amine oxidase, copper containing 1 Rattus norvegicus 128-132 8366761-2 1993 ODC and polyamines (putrescine, spermidine, spermine, and cadaverine) have an essential role in cell proliferation. Cadaverine 58-68 ornithine decarboxylase 1 Homo sapiens 0-3 1417947-1 1992 Three electrophilic homologous aminoalkylaziridine analogues of putrescine, cadaverine, and 1,3-diaminopropane were synthesized and found to represent a mechanistically distinct class of irreversible inhibitors of diamine oxidase. Cadaverine 76-86 amine oxidase copper containing 1 Homo sapiens 214-229 1503383-4 1992 Previous radiometric methods for DAO used tritiated putrescine or cadaverine as substrate. Cadaverine 66-76 amine oxidase copper containing 1 Homo sapiens 33-36 16668466-11 1991 The activity of diamine oxidase, the cadaverine degrading enzyme, started to increase at the third day and reached a maximum between the fourth and fifth day of germination. Cadaverine 37-47 copper amino oxidase Glycine max 16-31 1850732-5 1991 Evidence that N-(3-aminopropyl)cadaverine can also act as the amine substrate for deoxyhypusine synthase in intact cells was obtained by incubating putrescine- and spermidine-depleted Chinese hamster ovary cells with [3H]cadaverine. Cadaverine 31-41 deoxyhypusine synthase Cricetulus griseus 82-104 1799365-0 1991 Competition of homologous substrates, putrescine and cadaverine, in the reaction catalyzed by pea diamine oxidase. Cadaverine 53-63 amine oxidase copper containing 1 Homo sapiens 98-113 1799365-1 1991 The determination of diamine oxidase activity with the ninhydrin reagent was used for monitoring of simultaneous oxidation of two homologous substrates, putrescine and cadaverine, which give different colour products (519 and 417 nm). Cadaverine 168-178 amine oxidase copper containing 1 Homo sapiens 21-36 34331403-8 2021 This genera seems to affect the bile acid metabolism and cadaverine which may account for the improvement in insulin levels. Cadaverine 57-67 insulin Homo sapiens 109-116 34600890-6 2021 Docking and site-directed mutagenesis analyses show that both sTAAR365 and mTAAR9 recognize the two amino groups of cadaverine with the conserved Asp3.32 and Tyr6.51 residues. Cadaverine 116-126 trace amine-associated receptor 9 Mus musculus 75-81 34474093-4 2021 The DAO-1 showed a broad substrate selectivity with tyramine, histamine, putrescine and cadaverine being the most favored substrates. Cadaverine 88-98 amine oxidase copper containing 1 Homo sapiens 4-9 34560100-2 2021 The polyamines putrescine, agmatine and cadaverine, are produced by pyridoxal 5"-phosphate-dependent L-ornithine, L-arginine and L-lysine decarboxylases (ODC, ADC, LDC), respectively, from both the alanine racemase (AR) and aspartate aminotransferase (AAT) folds. Cadaverine 40-50 ornithine decarboxylase 1 Homo sapiens 154-157 34250670-5 2021 Exogenous supply of biotin and a pathway intermediate downstream of BIO1, 7,8-diaminopelargonic acid, suppressed this cadaverine sensitivity phenotype. Cadaverine 118-128 adenosylmethionine-8-amino-7-oxononanoate transaminase Arabidopsis thaliana 68-72 34250670-6 2021 An in vitro enzyme assay showed cadaverine inhibits the BIO3-BIO1 activity. Cadaverine 32-42 adenosylmethionine-8-amino-7-oxononanoate transaminase Arabidopsis thaliana 61-65 34250670-7 2021 Furthermore, cadaverine-treated seedlings displayed reduced biotinylation of Biotin Carboxyl Carrier Protein 1 (BCCP1) of the Acetyl-CoA Carboxylase complex involved in de novo fatty acid biosynthesis, resulting in decreased accumulation of triacylglycerides. Cadaverine 13-23 chloroplastic acetylcoenzyme A carboxylase 1 Arabidopsis thaliana 77-110 34250670-7 2021 Furthermore, cadaverine-treated seedlings displayed reduced biotinylation of Biotin Carboxyl Carrier Protein 1 (BCCP1) of the Acetyl-CoA Carboxylase complex involved in de novo fatty acid biosynthesis, resulting in decreased accumulation of triacylglycerides. Cadaverine 13-23 chloroplastic acetylcoenzyme A carboxylase 1 Arabidopsis thaliana 112-117 2758638-1 1989 This simple, rapid liquid-chromatographic assay of urinary polyamines (putrescine, spermidine, spermine, and cadaverine) involves electrochemical detection with a post-column immobilized enzyme, polyamine oxidase (EC 1.4.3.6) from soybean seedlings. Cadaverine 109-119 polyamine oxidase Homo sapiens 195-212 35308356-11 2022 The purified Odc1 protein decarboxylated lysine into cadaverine, while the recombinant Odc2 protein preferentially produced putrescine from ornithine but also exhibited low lysine decarboxylating activity. Cadaverine 53-63 ornithine decarboxylase 1 Homo sapiens 13-17 35177711-4 2022 Here, we used TAAR9 that recognizes important biogenic amines such as cadaverine, spermine, and spermidine as a model for entry tunnel study. Cadaverine 70-80 trace amine-associated receptor 9 Mus musculus 14-19 35154043-6 2021 In sausages spontaneously fermented and inoculated with Salmonella spp., the presence of cadaverine and putrescine diminished by 62 and 78%, respectively, due to the addition of cava lees. Cadaverine 89-99 carbonic anhydrase 5A Homo sapiens 178-182 35154043-7 2021 The addition of cava lees phenolic extract also showed an anti-aminogenic effect (21% for cadaverine and 40% for putrescine), although in a lesser extent than cava lees. Cadaverine 90-100 carbonic anhydrase 5A Homo sapiens 16-20 35572636-6 2022 Results: Mice lacking CYP1A1 exhibited an altered gut microbiome, a reduced metabolic shift from lysine to cadaverine in the caecal contents and antimicrobial molecule production (Retnlb, Gbp7, and Gbp3), and they were protected against gut barrier disruption when subjected to MRSA challenge. Cadaverine 107-117 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 22-28 35572636-7 2022 These beneficial effects were validated in aryl hydrocarbon receptor (AHR) knockout (KO) mice by cohousing with CYP1A1 KO mice and abrogated after supplementation with cadaverine or Enterococcus faecalis, the primary microbiota genus for cadaverine synthesis. Cadaverine 168-178 aryl-hydrocarbon receptor Mus musculus 43-68 35572636-7 2022 These beneficial effects were validated in aryl hydrocarbon receptor (AHR) knockout (KO) mice by cohousing with CYP1A1 KO mice and abrogated after supplementation with cadaverine or Enterococcus faecalis, the primary microbiota genus for cadaverine synthesis. Cadaverine 168-178 aryl-hydrocarbon receptor Mus musculus 70-73 35572636-7 2022 These beneficial effects were validated in aryl hydrocarbon receptor (AHR) knockout (KO) mice by cohousing with CYP1A1 KO mice and abrogated after supplementation with cadaverine or Enterococcus faecalis, the primary microbiota genus for cadaverine synthesis. Cadaverine 238-248 aryl-hydrocarbon receptor Mus musculus 70-73 35572636-11 2022 Conclusion: This study revealed the unexpected function of host CYP1A1 in microbiota-mediated cadaverine metabolism, with crucial consequences for dysbacteriosis following MRSA-induced abdominal sepsis, indicating that inhibiting CYP1A1 or blocking cadaverine-histamine H4 receptor signaling could be a potential therapeutic target against abdominal sepsis. Cadaverine 94-104 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 64-70 35572636-11 2022 Conclusion: This study revealed the unexpected function of host CYP1A1 in microbiota-mediated cadaverine metabolism, with crucial consequences for dysbacteriosis following MRSA-induced abdominal sepsis, indicating that inhibiting CYP1A1 or blocking cadaverine-histamine H4 receptor signaling could be a potential therapeutic target against abdominal sepsis. Cadaverine 94-104 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 230-236 3366303-2 1988 Partially purified rat liver ornithine decarboxylase is inhibited by several diamines including putrescine, 1,3-diaminopropane, cadaverine and p-phenylenediamine. Cadaverine 128-138 ornithine decarboxylase 1 Rattus norvegicus 29-52 3122732-0 1987 Cadaverine supplementation during a chronic exposure to difluoromethylornithine allows an overexpression, but prevents gene amplification, of ornithine decarboxylase in L1210 mouse leukaemia cells. Cadaverine 0-10 ornithine decarboxylase, structural 1 Mus musculus 142-165 3122732-1 1987 We recently selected a variant mouse L1210 leukaemia-cell line overproducing ornithine decarboxylase (ODC) (EC 4.1.1.17) as a result of chronic exposure to 2-difluoromethylornithine (DFMO) in the presence of micromolar concentrations of cadaverine. Cadaverine 237-247 ornithine decarboxylase, structural 1 Mus musculus 77-100 3122732-1 1987 We recently selected a variant mouse L1210 leukaemia-cell line overproducing ornithine decarboxylase (ODC) (EC 4.1.1.17) as a result of chronic exposure to 2-difluoromethylornithine (DFMO) in the presence of micromolar concentrations of cadaverine. Cadaverine 237-247 ornithine decarboxylase, structural 1 Mus musculus 102-105 3122732-5 1987 Omission of cadaverine from the culture medium, but leaving 10 mM-DFMO, resulted in an about 10-fold ODC gene amplification within a few weeks. Cadaverine 12-22 ornithine decarboxylase, structural 1 Mus musculus 101-104 6436440-1 1984 1-Piperideine, 5-aminopentanoic acid, and its lactam, 2-piperidone, were identified as metabolites of cadaverine in 10,000 g mouse liver supernatants to which diamine oxidase had been added. Cadaverine 102-112 amine oxidase, copper-containing 1 Mus musculus 159-174 16665078-1 1986 Exposing etiolated pea seedlings to ethylene which inhibited the activity of arginine decarboxylase and S-adenosylmethionine decarboxylase caused an increase in the level of cadaverine. Cadaverine 174-184 antizyme inhibitor 2 Homo sapiens 77-99 3987688-1 1985 The yeast Candida boidinii when grown on spermidine, diaminopropane, putrescine or cadaverine as sole nitrogen source contains an N-acetyltransferase capable of acetylating the primary amino groups of spermine, spermidine, acetylspermidines, acetylputrescine and alpha, omega-diaminoalkanes. Cadaverine 83-93 acetyltransferase Saccharomyces cerevisiae S288C 132-149 3106087-1 1987 When the cyanide complex of the copper protein, pig kidney diamine oxidase, is reduced anaerobically by cadaverine (1,5-diaminopentane), the broad, 480 nm, absorption band characteristic of the resting enzyme is bleached and a new absorption spectrum with features at 457, 429, 403 (shoulder), 360 (shoulder) and 332 nm appears. Cadaverine 104-114 amine oxidase copper containing 1 Sus scrofa 59-74 3106087-1 1987 When the cyanide complex of the copper protein, pig kidney diamine oxidase, is reduced anaerobically by cadaverine (1,5-diaminopentane), the broad, 480 nm, absorption band characteristic of the resting enzyme is bleached and a new absorption spectrum with features at 457, 429, 403 (shoulder), 360 (shoulder) and 332 nm appears. Cadaverine 116-134 amine oxidase copper containing 1 Sus scrofa 59-74 3937520-0 1985 Gene expression of ornithine decarboxylase in L1210 leukaemia cells exposed to DL-2-difluoromethylornithine in the presence of cadaverine. Cadaverine 127-137 ornithine decarboxylase, structural 1 Mus musculus 19-42 3937520-1 1985 Cultured mouse L1210 leukaemia cells treated with DL-2-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase (EC 4.1.1.17), in the presence of micromolar concentrations of cadaverine, started to overproduce ornithine decarboxylase after an exposure of several weeks. Cadaverine 196-206 ornithine decarboxylase, structural 1 Mus musculus 109-132 3841480-1 1985 Hydroxylamine-containing analogues of putrescine and cadaverine have been found effective in inhibiting the mouse liver ornithine decarboxylase, the best among synthesized were 1-aminooxy-3-aminopropane (I50 2.10(-8) M) and 1-aminooxy-4-aminobutane (I50 2.10(-7) M). Cadaverine 53-63 ornithine decarboxylase, structural 1 Mus musculus 120-143 6615435-2 1983 It was found that both phospholipid-sensitive Ca2+-dependent protein kinase and myosin light-chain kinase (a calmodulin-sensitive species of Ca2+-dependent protein kinase) were inhibited to different degrees by polyamines, with an approximate order of inhibitory potency of spermine = 1, 12-diaminododecane greater than spermidine = 1, 10-diaminodecane much greater than cadaverine = putrescine. Cadaverine 371-381 myosin light chain kinase Rattus norvegicus 80-105 6747294-15 1984 The formation of covalent bonds between IgG and C3 and probably C4 was essential for inhibition of immune precipitation, because inhibitors of their formation, such as putrescine, cadaverine, and salicylhydroxamic acid, effectively prevented the inhibition of precipitation. Cadaverine 180-190 complement C4A (Rodgers blood group) Homo sapiens 64-66 6148101-5 1984 For both dansylcadaverine and Glc-Glc-Glc(OH)-cadaverine, 5 and 8 mol of donor were incorporated per mol of amidinated and succinylated beta-casein, respectively. Cadaverine 15-25 casein beta Homo sapiens 136-147 6425061-3 1984 20 mM lysine, 1,2-diaminoethane, 1,3-diaminopropane, 1,4-diaminobutane or 1,5-diaminopentane are able to dissociate C1 into its two entities, C1q and the calcium-dependent C1r2-C1s2 complex. Cadaverine 74-92 complement C1q A chain Homo sapiens 142-145 6430782-2 1984 Dimeric subunits were visualized in UV light as monodansyl cadaverine bound to casein at the position of the transglutaminase activity representing F13A. Cadaverine 59-69 coagulation factor XIII A chain Homo sapiens 148-152 6615435-2 1983 It was found that both phospholipid-sensitive Ca2+-dependent protein kinase and myosin light-chain kinase (a calmodulin-sensitive species of Ca2+-dependent protein kinase) were inhibited to different degrees by polyamines, with an approximate order of inhibitory potency of spermine = 1, 12-diaminododecane greater than spermidine = 1, 10-diaminodecane much greater than cadaverine = putrescine. Cadaverine 371-381 calmodulin 1 Rattus norvegicus 109-119 6790686-1 1981 Hog kidney diamine oxidase (DAO) interacted with 1,3-diaminopropane, putrescine and cadaverine to arrest proliferation of cultured mammalian cells. Cadaverine 84-94 amine oxidase copper containing 1 Homo sapiens 11-26 6408913-4 1983 The oxidative products of cadaverine might be of importance in various physiological and pathophysiological connections associated with elevated diamine oxidase levels. Cadaverine 26-36 amine oxidase, copper containing 1 Rattus norvegicus 145-160 6805462-6 1982 Spermidine oxidase activity and diamine oxidase activity eluted in a concerted fashion when pregnancy serum was subjected to cadaverine-Sepharose chromatography, gel filtration and ion-exchange chromatography. Cadaverine 125-135 amine oxidase copper containing 1 Homo sapiens 32-47 6790686-1 1981 Hog kidney diamine oxidase (DAO) interacted with 1,3-diaminopropane, putrescine and cadaverine to arrest proliferation of cultured mammalian cells. Cadaverine 84-94 amine oxidase copper containing 1 Homo sapiens 28-31 7238568-7 1981 Mouse amniotic fluid was found to contain high levels of a spermine oxidase having a somewhat different specificity than that in FCS, and this enzyme produced a noncytotoxic immune inhibitor from cadaverine, spermidine and spermine. Cadaverine 196-206 spermine oxidase Mus musculus 59-75 7435118-1 1980 In the ovaries of pre-pubertal rats stimulated by human chorionic gonadotrophin (hCG) the temporal changes in cadaverine and putrescine formation were investigated. Cadaverine 110-120 chorionic gonadotropin subunit beta 5 Homo sapiens 81-84 7435118-3 1980 The results show that the ovary stimulated by hCG, in addition to putrescine, forms cadaverine at a highly increased rate. Cadaverine 84-94 chorionic gonadotropin subunit beta 5 Homo sapiens 46-49 7435118-5 1980 Treatment with aminoguanidine elevated the content of cadaverine in the ovary, suggesting that diamine oxidase has a role as a regulator of the intra-ovary level of cadaverine. Cadaverine 54-64 amine oxidase copper containing 1 Homo sapiens 95-110 7435118-5 1980 Treatment with aminoguanidine elevated the content of cadaverine in the ovary, suggesting that diamine oxidase has a role as a regulator of the intra-ovary level of cadaverine. Cadaverine 165-175 amine oxidase copper containing 1 Homo sapiens 95-110 7205597-2 1980 The diamines (1,3-propanediamine, 1,5-pentanediamine, and 1,6-hexanediamine) dramatically decreased neuroblastoma replication and inhibited the rate-limiting enzyme, ornithine decarboxylase. Cadaverine 34-52 ornithine decarboxylase 1 Homo sapiens 166-189 7190634-0 1980 The dual action of the non-physiological diamines 1,3 diaminopropane and cadaverine on ornithine decarboxylase of HTC cells. Cadaverine 73-83 ornithine decarboxylase 1 Rattus norvegicus 87-110 110032-5 1979 Treatment with aminoguanidine generally elevated the content of cadaverine, indicating a role of diamine oxidase as a regulator of diamine content. Cadaverine 64-74 amine oxidase, copper containing 1 Rattus norvegicus 97-112 7228251-8 1980 The formation of NPYR and NPIP from proline, pyrrolidine, putrescine, spermidine and cadaverine was studied in a model experiment, using minced bacon as the reaction medium. Cadaverine 85-95 neuropeptide Y receptor Y1 Homo sapiens 17-21 486492-8 1979 These experiments indicate that all of the detectable lysine decarboxylase activity in rat and mouse tissues was due to the action of ornithine decarboxylase and that significant cadaverine production in vivo would occur only when ornithine decarboxylase activity is high and lysine concentrations substantially exceed those of ornithine. Cadaverine 179-189 ornithine decarboxylase, structural 1 Mus musculus 231-254 901422-10 1977 Cadaverine (1,5-diaminopentane) and 1,6-diaminohexane were the most potent inhibitors of ornithine decarboxylase among the amines tested. Cadaverine 0-10 ornithine decarboxylase, structural 1 Mus musculus 89-112 646807-1 1978 Rat liver ornithine decarboxylase activity was decreased by administration of putrescine (1,4-diaminobutane) or other diamines, including 1,3-diaminopropane, 1,5-diaminopentane and 1,6-diaminohexane. Cadaverine 158-176 ornithine decarboxylase 1 Rattus norvegicus 10-33 901422-10 1977 Cadaverine (1,5-diaminopentane) and 1,6-diaminohexane were the most potent inhibitors of ornithine decarboxylase among the amines tested. Cadaverine 12-30 ornithine decarboxylase, structural 1 Mus musculus 89-112 32816235-0 2021 Cadaverine and Spermine Elicit Ca2+ Uptake in Human CP Cells via a Trace Amine-Associated Receptor 1 Dependent Pathway. Cadaverine 0-10 trace amine associated receptor 1 Homo sapiens 67-100 402498-2 1977 It metabolises also a variety of diamines such as putrescine and cadaverine and is generally accepted to be identical with histaminase. Cadaverine 65-75 amine oxidase copper containing 1 Homo sapiens 123-134 178010-1 1975 When the diamines putrescine, cadaverine, cystamine and lanthionamine are oxidized by purified pig kidney diamine oxidase in the presence of NADH and either liver or yeast crystalline alcohol dehydrogenase, NADH is oxidized. Cadaverine 30-40 amine oxidase copper containing 1 Sus scrofa 106-121 4963523-0 1967 The inactivation of pea-seedling diamine oxidase by peroxidase and 1,5-diaminopentane. Cadaverine 67-85 amine oxidase copper containing 1 Homo sapiens 33-48 4963523-2 1967 The rate of oxidative deamination of 1,5-diaminopentane by pea-seedling extracts, which contain diamine oxidase [diamine-oxygen oxidoreductase (deaminating), EC 1.4.3.6], was increased by adding pyridoxal or pyridoxal phosphate. Cadaverine 37-55 amine oxidase copper containing 1 Homo sapiens 96-111 4963523-6 1967 This inactivation only occurred when 1,5-diaminopentane was the substrate and depended on a second thermolabile factor in the extract besides the diamine oxidase. Cadaverine 37-55 amine oxidase copper containing 1 Homo sapiens 146-161 4963523-8 1967 Purified diamine oxidase, when catalysing the oxidation of 1,5-diaminopentane, was rapidly inactivated in the presence of peroxidase. Cadaverine 59-77 amine oxidase copper containing 1 Homo sapiens 9-24 4963523-12 1967 It is suggested that peroxidase catalyses the further oxidation of the product of the oxidative deamination of 1,5-diaminopentane to a compound that inactivates diamine oxidase. Cadaverine 111-129 amine oxidase copper containing 1 Homo sapiens 161-176 4963469-0 1967 Oxidative deamination of 2-hydroxy derivatives of putrescine and cadaverine by pea-seedling and pig-kidney diamine oxidase. Cadaverine 65-75 amine oxidase copper containing 1 Sus scrofa 107-122 32816235-9 2021 Calcium imaging assays after TAAR1 knockdown in these cells with a specific siRNA against TAAR1 showed a consistent reduction in the responses of these cells to cadaverine and spermidine, but not to spermine, suggesting that TAAR1 is activated by cadaverine and spermidine, but not spermine. Cadaverine 247-257 trace amine associated receptor 1 Homo sapiens 90-95 32816235-9 2021 Calcium imaging assays after TAAR1 knockdown in these cells with a specific siRNA against TAAR1 showed a consistent reduction in the responses of these cells to cadaverine and spermidine, but not to spermine, suggesting that TAAR1 is activated by cadaverine and spermidine, but not spermine. Cadaverine 247-257 trace amine associated receptor 1 Homo sapiens 90-95 808238-2 1975 The procedure is based upon the binding of histaminase to cadaverine, a diamine substrate for the enzyme, which is coupled to Sepharose. Cadaverine 58-68 amine oxidase copper containing 1 Homo sapiens 43-54 808238-4 1975 The purification technique has the following characteristics: (1) in optimal experiments, 3000-fold purification of enzyme was obtained; (2) the yield of enzyme was as great as 25%; (3) the binding of histaminase to the amine groups of the cadaverine appears to represent a true "affinity" phenomenon since enzyme bound to DEAE-cellulose under neutral pH conditions was eluted at much lower concentrations of NaCl (less than 0.4 M). Cadaverine 240-250 amine oxidase copper containing 1 Homo sapiens 201-212 33545502-6 2021 Moreover, L-tryptophan, cadaverine and D-pantothenic acid could serve as the diagnostic biomarker for NTCP deficiency. Cadaverine 24-34 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 Mus musculus 102-106 32816235-6 2021 The zebrafish TAAR13c was the only receptor known to bind a polyamine-cadaverine. Cadaverine 70-80 trace amine associated receptor 13c Danio rerio 14-21 32816235-9 2021 Calcium imaging assays after TAAR1 knockdown in these cells with a specific siRNA against TAAR1 showed a consistent reduction in the responses of these cells to cadaverine and spermidine, but not to spermine, suggesting that TAAR1 is activated by cadaverine and spermidine, but not spermine. Cadaverine 161-171 trace amine associated receptor 1 Homo sapiens 29-34 32816235-9 2021 Calcium imaging assays after TAAR1 knockdown in these cells with a specific siRNA against TAAR1 showed a consistent reduction in the responses of these cells to cadaverine and spermidine, but not to spermine, suggesting that TAAR1 is activated by cadaverine and spermidine, but not spermine. Cadaverine 161-171 trace amine associated receptor 1 Homo sapiens 90-95 32816235-9 2021 Calcium imaging assays after TAAR1 knockdown in these cells with a specific siRNA against TAAR1 showed a consistent reduction in the responses of these cells to cadaverine and spermidine, but not to spermine, suggesting that TAAR1 is activated by cadaverine and spermidine, but not spermine. Cadaverine 161-171 trace amine associated receptor 1 Homo sapiens 90-95 33144591-12 2020 TMA and cadaverine inhibited LPS-stimulated TNF-alpha and IL-6 secretion by primary human monocytes. Cadaverine 8-18 tumor necrosis factor Homo sapiens 44-53 33144591-12 2020 TMA and cadaverine inhibited LPS-stimulated TNF-alpha and IL-6 secretion by primary human monocytes. Cadaverine 8-18 interleukin 6 Homo sapiens 58-62 31638822-8 2020 One or two secondary glutamine residues of only P-H, P-D P32, P-C and statherin were hierarchically susceptible to the reaction with monodansyl-cadaverine. Cadaverine 133-154 statherin Homo sapiens 48-79 32488317-3 2020 METHODS AND RESULTS: Condensation of ortho-aminobenzaldehyde (oABA) with delta-1-pyrroline and delta-1-piperideine, the autocyclization products of the DAO-oxidized natural substrates putrescine and cadaverine, generates new quinazoline fluorophores with absorption and excitation maxima of 430 and 460 nm, respectively, and peak emission at 620 nm. Cadaverine 199-209 amine oxidase copper containing 1 Homo sapiens 152-155 32488317-8 2020 CONCLUSIONS: Incubation of DAO with the natural substrates putrescine and cadaverine and oABA generates novel fluorophores increasing the detection limit compared to absorption measurements at least tenfold. Cadaverine 74-84 D-amino acid oxidase Mus musculus 27-30 29274298-6 2018 This allows monitoring the dynamic progress of the conversion of lysine to cadaverine with a temporal resolution of ~30 s. Moreover, the method only requires to sample the very early onset of the reaction (<0.5% of substrate conversion where the host itself is required only at muM concentrations) at comparatively low reaction rates, thus saving enzyme material and reducing NMR acquisition time. Cadaverine 75-85 latexin Homo sapiens 281-284 33405720-11 2019 The incorporation of fluorescently labeled cadaverine derivatives for the detection of active TGase 2 was in accordance with the results of the expression analysis. Cadaverine 43-53 transglutaminase 2, C polypeptide Mus musculus 94-101 33405720-12 2019 The presence of an irreversible inhibitor of TGase 2 led to attenuated incorporation of the cadaverines, which verified the catalytic action of TGase 2. Cadaverine 92-103 transglutaminase 2, C polypeptide Mus musculus 45-52 33405720-12 2019 The presence of an irreversible inhibitor of TGase 2 led to attenuated incorporation of the cadaverines, which verified the catalytic action of TGase 2. Cadaverine 92-103 transglutaminase 2, C polypeptide Mus musculus 144-151 31509528-7 2019 xlAZIN2 did not behave as an antizyme inhibitor, but it rather acts as an authentic decarboxylase forming cadaverine, due to its higher affinity to L-lysine than to L-ornithine as substrate; so, in accordance with this, it should be named as lysine decarboxylase (LDC) or lysine/ornithine decarboxylase (LODC). Cadaverine 106-116 antizyme inhibitor 2 S homeolog Xenopus laevis 0-7 31509528-7 2019 xlAZIN2 did not behave as an antizyme inhibitor, but it rather acts as an authentic decarboxylase forming cadaverine, due to its higher affinity to L-lysine than to L-ornithine as substrate; so, in accordance with this, it should be named as lysine decarboxylase (LDC) or lysine/ornithine decarboxylase (LODC). Cadaverine 106-116 ornithine decarboxylase, structural 1 Mus musculus 279-302 31088617-4 2019 In this study, we introduced an ATP regeneration system using polyphosphate kinase (ppk) into systems containing cadaverine decarboxylase (CadA) and PdxY for a sufficient supply of PLP, which resulted in enhanced cadaverine production. Cadaverine 113-123 pyridoxal phosphatase Homo sapiens 181-184 31367038-6 2019 We reveal a connection between polyamine and lysine metabolism during stress situations, in the form of a promiscuous enzymatic reaction in which the first enzyme of the polyamine pathway, Spe1p, decarboxylates lysine and forms an alternative polyamine, cadaverine. Cadaverine 254-264 ornithine decarboxylase SPE1 Saccharomyces cerevisiae S288C 189-194 30718646-7 2019 Trace amino acid receptors (TAARs), namely, TAAR1, TAAR8 and TAAR9 were instrumental in provoking the cadaverine-evoked effects. Cadaverine 102-112 trace amine associated receptor 1 Homo sapiens 44-49 30718646-7 2019 Trace amino acid receptors (TAARs), namely, TAAR1, TAAR8 and TAAR9 were instrumental in provoking the cadaverine-evoked effects. Cadaverine 102-112 trace amine associated receptor 8 Homo sapiens 51-56 30718646-7 2019 Trace amino acid receptors (TAARs), namely, TAAR1, TAAR8 and TAAR9 were instrumental in provoking the cadaverine-evoked effects. Cadaverine 102-112 trace amine associated receptor 9 Homo sapiens 61-66 30021117-2 2018 However, ODC also has minor activity towards cell metabolite C6 lysine and yields C5 cadaverine. Cadaverine 85-95 ornithine decarboxylase 1 Homo sapiens 9-12 30021117-7 2018 This corresponds to four-fold decrease in cadaverine yield compared to the native ODC. Cadaverine 42-52 ornithine decarboxylase 1 Homo sapiens 82-85 29080172-2 2018 Here we describe the methods used in a Quantitative Trait Loci (QTL) study that allowed the identification of ORGANIC CATION TRANSPORTER 1 (OCT1) as a determinant of root growth response to cadaverine treatment in Arabidopsis thaliana. Cadaverine 190-200 organic cation/carnitine transporter1 Arabidopsis thaliana 110-138 29941999-2 2018 TAAR13c, the zebrafish olfactory receptor activated by the death-associated odor cadaverine, appears to possess an allosteric binding site for cadaverine, which was assumed to block progress of the ligand towards the internal orthosteric binding-and-activation site. Cadaverine 81-91 trace amine associated receptor 13c Danio rerio 0-7 29941999-2 2018 TAAR13c, the zebrafish olfactory receptor activated by the death-associated odor cadaverine, appears to possess an allosteric binding site for cadaverine, which was assumed to block progress of the ligand towards the internal orthosteric binding-and-activation site. Cadaverine 143-153 trace amine associated receptor 13c Danio rerio 0-7 29080172-2 2018 Here we describe the methods used in a Quantitative Trait Loci (QTL) study that allowed the identification of ORGANIC CATION TRANSPORTER 1 (OCT1) as a determinant of root growth response to cadaverine treatment in Arabidopsis thaliana. Cadaverine 190-200 organic cation/carnitine transporter1 Arabidopsis thaliana 140-144 28102357-1 2017 The death-associated odor cadaverine, generated by bacteria-mediated decarboxylation of lysine, has been described as the principal activator of a particular olfactory receptor in zebrafish, TAAR13c. Cadaverine 26-36 trace amine associated receptor 13c Danio rerio 191-198 28102357-2 2017 Low concentrations of cadaverine activated mainly TAAR13c-expressing olfactory sensory neurons, suggesting TAAR13c as an important element of the neuronal processing pathway linking cadaverine stimulation to a strongly aversive innate behavioral response. Cadaverine 22-32 trace amine associated receptor 13c Danio rerio 50-57 28102357-2 2017 Low concentrations of cadaverine activated mainly TAAR13c-expressing olfactory sensory neurons, suggesting TAAR13c as an important element of the neuronal processing pathway linking cadaverine stimulation to a strongly aversive innate behavioral response. Cadaverine 22-32 trace amine associated receptor 13c Danio rerio 107-114 28102357-2 2017 Low concentrations of cadaverine activated mainly TAAR13c-expressing olfactory sensory neurons, suggesting TAAR13c as an important element of the neuronal processing pathway linking cadaverine stimulation to a strongly aversive innate behavioral response. Cadaverine 182-192 trace amine associated receptor 13c Danio rerio 107-114 27303024-6 2016 Transgenic tobacco (Nicotiana tabacum) hairy roots and Arabidopsis (Arabidopsis thaliana) plants expressing LcL/ODC enhanced the production of a Lys-derived alkaloid, anabasine, and cadaverine, respectively, thus, confirming the function of LcL/ODC in plants. Cadaverine 182-192 ornithine decarboxylase-like Nicotiana tabacum 112-115