PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 2482075-2 1989 Increasing binding of MBP to DMPG bilayers resulted in an increasing motional restriction of PG spin-labeled at the C-5 atom position in the acyl chain, up to a maximum degree of association of 1 MBP molecule per 36 lipid molecules. Carbon 116-117 myelin basic protein Bos taurus 22-25 2482076-9 1989 Both the fragments and the MBP decreased the lipid chain mobility as recorded by the C-5 atom and C-12 atom position nitroxide-PG spin-labels, in a manner which followed the protein binding curves. Carbon 85-86 myelin basic protein Bos taurus 27-30 2621423-4 1989 The retention times of the molecular species on the C18 reversed-phase column were longer with increasing carbon chain length and decreasing degree of unsaturation of fatty acyl chain. Carbon 106-112 Bardet-Biedl syndrome 9 Homo sapiens 52-55 2611236-3 1989 The latter two conformers may be distinguished by smaller but still significant differences in the carbon chemical shifts at the C-2" and C-4" positions. Carbon 99-105 complement C4 Bos taurus 138-141 2557833-3 1989 The results obtained indicate that: (i) membrane-entrapped microperoxidase undergoes rapid reversible electron transfer at a glassy carbon electrode; (ii) the electrochemical process is diffusion-controlled; (iii) entrapped microperoxidase acts as "solid-state" promoter in the electrochemistry of soluble cytochrome c and of azurin. Carbon 132-138 cytochrome c, somatic Homo sapiens 306-318 2610336-3 1989 158, 228-232) for measuring cholesterol 7 alpha-hydroxylase activity was modified by using a C-18 reverse-phase column to separate 7 alpha-hydroxy-4-cholesten-3-one and 4-cholesten-3-one and by adding 7 beta-hydroxycholesterol to each reaction mixture as an internal recovery standard. Carbon 93-94 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 28-59 2604035-5 1989 Because of the wide linear range of this method (0.2-700 micrograms/ml), trace levels of C-10, C-14, C-16, C-18, and C-20 alkyl sulfates can be accurately measured in the presence of high concentrations of C-12 alkyl sulfate (SDS). Carbon 89-90 Bardet-Biedl syndrome 9 Homo sapiens 107-111 2553290-10 1989 The epoxidizing peroxyl radicals could not be detected but their precursors, carbon-centered radicals, were detected by using the ESR spin trapping technique in incubations of 15-lipoxygenase with 15-HPETE. Carbon 77-83 arachidonate 15-lipoxygenase Homo sapiens 176-191 2605196-3 1989 The compound (5,5,5-trifluoro-4-oxopentyl)trimethylammonium bicarbonate (1) inhibits acetylcholinesterase with Ki = 0.06 X 10(-9)M and pseudocholinesterase with Ki = 70 X 10(-9)M. Replacement of the nitrogen of 1 by carbon (compound 2) increases Ki for 1 200-fold for acetylcholinesterase but does not significantly alter Ki for pseudocholinesterase. Carbon 62-68 acetylcholinesterase (Cartwright blood group) Homo sapiens 85-105 2605196-3 1989 The compound (5,5,5-trifluoro-4-oxopentyl)trimethylammonium bicarbonate (1) inhibits acetylcholinesterase with Ki = 0.06 X 10(-9)M and pseudocholinesterase with Ki = 70 X 10(-9)M. Replacement of the nitrogen of 1 by carbon (compound 2) increases Ki for 1 200-fold for acetylcholinesterase but does not significantly alter Ki for pseudocholinesterase. Carbon 62-68 acetylcholinesterase (Cartwright blood group) Homo sapiens 268-288 2677036-5 1989 Insulin was suppressed by 55% only during hypothermia, peaking with rewarming in C+ at 2,849 +/- 911 vs. 639 +/- 251 pmol/L in C- (P less than 0.05); as with glycemia, values were comparable after 2 h postop. Carbon 81-82 insulin Homo sapiens 0-7 2551897-1 1989 Porcine submaxillary beta-galactoside alpha(1----2)-fucosyltransferase is known to transfer a fucosyl residue from guanosine 5"-diphosphofucose (GDP-fucose) to the 2-OH group of beta-D-galactopyranosides with inversion of configuration at the fucopyranosyl anomeric carbon. Carbon 266-272 fucosyltransferase 2 Homo sapiens 38-70 2561133-5 1989 These results suggest that the replacement of a carbon atom into an oxygen atom in the side chain structure of 1,25-D3 results significant decrease in the binding affinity to DBP and that 22-oxa-1,25-D3 is transported as a complex-form not with DBP but with lipoprotein to the target tissues. Carbon 48-54 D-box binding PAR bZIP transcription factor Homo sapiens 175-178 11538326-4 1989 If the carbon abundance is high and grain surface reactions are the dominant formation route, H2CS would be expected to form instead of H2S, and the abundances of H2CS have been observed to be high where those of H2S are low in L134N and TMC 1. Carbon 7-13 transmembrane channel like 1 Homo sapiens 238-243 2561133-5 1989 These results suggest that the replacement of a carbon atom into an oxygen atom in the side chain structure of 1,25-D3 results significant decrease in the binding affinity to DBP and that 22-oxa-1,25-D3 is transported as a complex-form not with DBP but with lipoprotein to the target tissues. Carbon 48-54 D-box binding PAR bZIP transcription factor Homo sapiens 245-248 2551729-7 1989 The 30 kDa N-tryptic fragment (residues 4-281) and the re-associated N,C-tryptic complex bind to lactotansferrin lymphocyte receptor with a dissociation constant of 44 nM and 39 nM, respectively, similar to the value obtained for the native lactotransferrin (Kd = 46 nM). Carbon 71-72 lactotransferrin Homo sapiens 241-257 34034434-1 1989 The assignment of the proton and carbon spectra of the cyclic peptide cyclo(-Phe1 -Pro2 -Thr3 -Lys(Z)4 -Trp5 -Phe6 -) was accomplished by the application of multiple quantum proton-detected heteronuclear correlation spectroscopy. Carbon 33-39 transient receptor potential cation channel subfamily C member 5 Homo sapiens 104-108 2794167-6 1989 Milk fat concentration was increased by even-carbon, medium-chain triglyceride supplementation relative to odd-carbon, medium-chain triglyceride supplementation (3.44 vs. 2.99%). Carbon 45-51 Weaning weight-maternal milk Bos taurus 0-4 2751989-7 1989 Calculations are carried out for C-14, C-16, and C-18 chains. Carbon 0-1 Bardet-Biedl syndrome 9 Homo sapiens 49-53 2757954-4 1989 An analogous substitution pattern on the steroid D-ring or the carbon side chain (C20, C21) seems to have a significant influence on the association of positive patchtest results. Carbon 63-69 TBL1X/Y related 1 Homo sapiens 87-90 2793970-3 1989 The reversed-phase (C18) chromatographic analysis with amperometric detection (glassy carbon electrode in oxidative mode, +0.6 V vs. Ag/AgCl) was found to be useful for the measurement of both baclofen and alpha-baclofen from 10 ng/ml to 10 micrograms/ml in these complex biological samples. Carbon 86-92 Bardet-Biedl syndrome 9 Homo sapiens 20-23 2468678-6 1989 Double patch-clamp experiments on pairs of acinar cells, under conditions of strong cytosolic Ca2+ and pH buffering, showed that C-7, C-8, and C-9 alcohols blocked completely and reversibly the electrical conductance of junctional channels. Carbon 94-95 complement C7 Rattus norvegicus 129-132 2468678-6 1989 Double patch-clamp experiments on pairs of acinar cells, under conditions of strong cytosolic Ca2+ and pH buffering, showed that C-7, C-8, and C-9 alcohols blocked completely and reversibly the electrical conductance of junctional channels. Carbon 94-95 complement C9 Rattus norvegicus 143-146 2468678-2 1989 In intact acini, alcohols with a chain of seven, eight, or nine carbons (C-7, C-8, and C-9) induced dye uncoupling and increased basal amylase release. Carbon 64-71 complement C7 Rattus norvegicus 73-76 2784981-5 1989 An average root-mean-square deviation of 1.6 A was obtained for the alpha-carbons of the first 63 residues in the calculated ensemble of C5a structures, while the alpha-helices were determined with an average root-mean-square deviation of 0.8 A for the alpha-carbons. Carbon 74-81 complement C5a receptor 1 Homo sapiens 137-140 2647491-10 1989 The haploid offsprings with the defective aldolase allele fba1::URA3 lack aldolase enzymatic activity and fail to grow in media containing as a carbon source metabolites of only one side of the aldolase reaction. Carbon 144-150 fructose-bisphosphate aldolase FBA1 Saccharomyces cerevisiae S288C 58-62 2918517-4 1989 It was found that the chemical oxidative dealkylation of N-masked NFLXs proceeded when anion-stabilizing groups (e.g., CN, COR, COOR) are present on the alpha carbon of the nitrogen atom. Carbon 159-165 distribution of corticosterone in adrenal cortex cells Mus musculus 123-126 2725527-2 1989 Earlier studies of the S14-containing chromatin region demonstrated that a cytosine residue at position 625 (C-625) in the 3" untranslated exon was hypermethylated in hepatic DNA derived from hypothyroid animals. Carbon 109-110 thyroid hormone responsive Rattus norvegicus 23-26 2914926-1 1989 The distance between the heme iron of ferrous cytochrome P-450-CAM and a fluorine label attached to the 9-methyl carbon of its substrate, (1R)-(+)-camphor, has been determined using 19F NMR. Carbon 113-119 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 46-62 2653438-9 1989 We conclude that aromatase attacks the 19-carbon of 19,19-difluoroandrost-4-ene-3,17-dione, as originally postulated. Carbon 42-48 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 17-26 2784981-5 1989 An average root-mean-square deviation of 1.6 A was obtained for the alpha-carbons of the first 63 residues in the calculated ensemble of C5a structures, while the alpha-helices were determined with an average root-mean-square deviation of 0.8 A for the alpha-carbons. Carbon 259-266 complement C5a receptor 1 Homo sapiens 137-140 3233207-19 1988 In DMPG the sn-1 C = O group seems to be more accessible to water, indicating a different conformation of the glycerol backbone. Carbon 17-18 solute carrier family 38 member 3 Homo sapiens 12-16 2853233-2 1988 Cyc mRNA levels are found to depend primarily on the presence of acetate as a reduced carbon source in the culture medium. Carbon 86-92 uncharacterized protein Chlamydomonas reinhardtii 0-3 2852136-2 1988 In aerobically grown wild-type yeast cells, Va is the predominant form of subunit V. The COX5b gene alone does not produce enough Vb to support a respiration rate sufficient to allow growth on nonfermentable carbon sources. Carbon 208-214 cytochrome c oxidase subunit Vb Saccharomyces cerevisiae S288C 89-94 2908851-7 1989 MOCA ring-oxidation and methylene carbon oxidation showed varied cytochrome P-450 selectivity and accounted for 14 to 79% of total oxidation products. Carbon 34-40 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 65-81 3223959-7 1988 It is concluded that both leukocyte 5-lipoxygenase and omega-hydroxylase exhibit a substrate specificity towards monohydroxylated fatty acids with respect to their double bonds and/or the carbon position of the alcohol function. Carbon 188-194 arachidonate 5-lipoxygenase Homo sapiens 36-50 3254896-2 1988 In NZB/WF1 mice over 9 weeks of age, many circulating carbon-laden macrophages were seen to have penetrated the walls of blood vessels, and to have then entered the thymic parenchyma. Carbon 54-60 TP53 regulated inhibitor of apoptosis 1 Mus musculus 7-10 3388956-5 1988 Particular attention was devoted to conformations about C-O bonds in different acyclic fragments, which demonstrated well-defined differences between 2",3"-seco derivatives on the one hand (conformational "rigidity") and derivatives with DHP and AC acyclic chains on the other (rotation about the C(1")-O(4") bond). Carbon 56-57 dihydropyrimidinase Homo sapiens 238-241 3138238-8 1988 Based on these findings, it is proposed that 4-ene- and 4-hydroxy-VPA are products of a common P-450-dependent metabolic pathway, in which a carbon-centered free radical at C-4 serves as the key intermediate. Carbon 141-147 complement C4A Rattus norvegicus 173-176 3365259-2 1988 In this study, it has been observed that the nodules show a large decrease in an additional cytochrome P-450, cytochrome P-452, which is very active in the hydroxylation of lauric acid at C-11 and C-12. Carbon 188-189 cytochrome P450, family 4, subfamily a, polypeptide 1 Rattus norvegicus 110-126 3365259-2 1988 In this study, it has been observed that the nodules show a large decrease in an additional cytochrome P-450, cytochrome P-452, which is very active in the hydroxylation of lauric acid at C-11 and C-12. Carbon 197-198 cytochrome P450, family 4, subfamily a, polypeptide 1 Rattus norvegicus 110-126 3063399-1 1988 A 870 bp promoter fragment of the PDC1 gene that includes the carbon source dependent regulatory regions was investigated using 5" and 3" promoter deletions. Carbon 62-68 indolepyruvate decarboxylase 1 Saccharomyces cerevisiae S288C 34-38 3137220-3 1988 In the crystal structure of native calmodulin alpha-carbons at positions 3 and 146 are 37 A apart. Carbon 52-59 calmodulin 1 Homo sapiens 35-45 3062132-3 1988 The macrocycle for vitamin B12 is smaller by one carbon than that for chlorophyll and protoheme. Carbon 49-55 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 27-30 3260238-6 1988 DAB cytochemistry caused approximately 40% of microsome-associated "complex" glycosylated [35S]alpha 1-antitrypsin ([35S]c-AT) to shift in a Percoll density gradient. Carbon 4-5 serpin family A member 1 Homo sapiens 95-114 3260238-10 1988 If in addition to Tf/HRP also an excess of non-conjugated transferrin was present in the medium, [35S]c-AT was not accessible for Tf/HRP, showing the involvement of the transferrin receptor (TfR) in the process. Carbon 35-36 transferrin Homo sapiens 58-69 3236220-2 1988 The bacterial strain mA3 capable of utilizing 3-aminophenol as the sole source of carbon, energy and nitrogen for growth was isolated from an enrichment culture and identified as an Arthrobacter species. Carbon 82-88 cholinergic receptor, nicotinic, alpha polypeptide 3 Mus musculus 21-24 3338873-8 1988 Injection of carbon particles showed that the development of capillaries in 7-day-old tumors was more extensive than in 3-day-old tumors, and suggested that the anti-tumor activity of rTNF-alpha depends upon a fully developed fine network of induced capillaries in the tumor. Carbon 13-19 tumor necrosis factor Rattus norvegicus 184-194 3349155-1 1988 In rats with CCl4-induced liver cirrhosis the clearance rate of colloid carbon particles was more than 2 times lower than in control animals. Carbon 72-78 C-C motif chemokine ligand 4 Rattus norvegicus 13-17 3429448-8 1987 An alignment of P-450(11 beta) and P-450(SCC) to give maximum matching showed four highly conserved regions (C-1, C-2, C-3, and C-4). Carbon 42-43 complement C4 Bos taurus 128-131 3280855-7 1988 During calcium citrate therapy, serum calcium was significantly higher, while C-PTH and serum alkaline phosphatase were significantly reduced. Carbon 78-79 parathyroid hormone Homo sapiens 80-83 2827010-1 1988 sra5 mutations in Saccharomyces cerevisiae were previously shown to suppress the inefficient growth of ras2 strains on nonfermentable carbon sources and to result in deficient low-Km cyclic AMP (cAMP) phosphodiesterase activity. Carbon 134-140 3',5'-cyclic-nucleotide phosphodiesterase PDE2 Saccharomyces cerevisiae S288C 0-4 3429448-8 1987 An alignment of P-450(11 beta) and P-450(SCC) to give maximum matching showed four highly conserved regions (C-1, C-2, C-3, and C-4). Carbon 43-44 complement C4 Bos taurus 128-131 3556837-1 1987 The metabolism of saturated nitriles, including acetonitrile, has been assumed to occur by a cytochrome P-450-dependent oxidation at the alpha-carbon, yielding a cyanohydrin intermediate which may spontaneously degrade to hydrogen cyanide and an aldehyde. Carbon 143-149 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 93-109 3040523-7 1987 ADR6 codes for a 4.4-kb RNA which is present during growth both on glucose and on nonfermentable carbon sources. Carbon 97-103 Swi1p Saccharomyces cerevisiae S288C 0-4 16665477-8 1987 A positive relationship between levels of PGA and those of pyruvate during steady-state photosynthesis under various conditions suggests that an elevated concentration of PGA increases the carbon input into the C(4) cycle through the conversion of PGA to PEP and consequently the level of total intermediates of the C(4) cycle can be raised to mediate higher photosynthesis rate. Carbon 189-195 phosphoenolpyruvate carboxylase 2 Zea mays 255-258 3611100-3 1987 13C NMR chemical shift results as a function of pH for a series of carboxyl 13C-enriched saturated fatty acids (8-18 carbons) bound to bovine serum albumin (BSA) are presented. Carbon 117-124 albumin Homo sapiens 142-155 3313003-2 1987 Expression of the ENO1 gene is quantitatively similar in cells grown on glucose or gluconeogenic carbon sources. Carbon 97-103 phosphopyruvate hydratase ENO1 Saccharomyces cerevisiae S288C 18-22 3313003-5 1987 A complex positive regulatory region was located 445 base pairs (bp) upstream from the transcriptional initiation site which was required for ENO1 expression in cells grown on glycolytic or gluconeogenic carbon sources. Carbon 204-210 phosphopyruvate hydratase ENO1 Saccharomyces cerevisiae S288C 142-146 3313003-12 1987 Based on these studies, we conclude that the negative regulatory element plays the critical role in maintaining the constitutive expression of the ENO1 structural gene in cells grown on glucose or gluconeogenic carbon sources. Carbon 211-217 phosphopyruvate hydratase ENO1 Saccharomyces cerevisiae S288C 147-151 3117041-11 1987 It is concluded that an early action of vasopressin on the liver cell is to increase the flux of carbon from phospholipids, including the phosphoinositides, to diacylglycerols. Carbon 97-103 arginine vasopressin Homo sapiens 40-51 2821168-3 1987 The synthesis of lipoamide dehydrogenase in yeast is subject to carbon catabolite repression since both the level of the LPD1 transcript and the accumulation of the lipoamide dehydrogenase subunit polypeptide were greatly reduced in wild-type cells grown on glucose compared to those grown on a variety of non-fermentable carbon sources. Carbon 64-70 dihydrolipoyl dehydrogenase Saccharomyces cerevisiae S288C 121-125 3625445-3 1987 On the other hand, saturated, monoenoic and dienoic mycolic acids with carbon atoms ranging from C36 to C50 contained constituents of fatty acid moiety at C44. Carbon 71-77 alpha-1-B glycoprotein Mus musculus 155-158 16665199-8 1987 Results of this study implied that galactinol synthase is an important regulator of carbon partitioning between sucrose and raffinose saccharides in developing soybean seeds. Carbon 84-90 galactinol synthase Glycine max 35-54 3806608-1 1987 Mammals metabolize the tobacco alkaloid (S)-nicotine primarily to the lactam (S)-cotinine by a pathway involving an initial cytochrome P-450 catalyzed two-electron oxidation at the prochiral 5"-carbon atom. Carbon 194-200 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 124-140 3783588-3 1986 Modification of the positions 5 and 6 with an alkyl group of 5-10 carbons markedly decreased the IC50 values for 5-lipoxygenase inhibition to the order of 10 nM. Carbon 66-73 arachidonate 5-lipoxygenase Homo sapiens 113-127 3782334-0 1986 Dependence of the separation of some biological substances on the carbon content of C18 chemically bonded phases. Carbon 66-72 Bardet-Biedl syndrome 9 Homo sapiens 84-87 3537717-1 1986 There are two yeast enolase genes, designated ENO1 and ENO2, which are expressed differentially in vegetative cells grown on glucose and in cells grown on gluconeogenic carbon sources. Carbon 169-175 phosphopyruvate hydratase ENO1 Saccharomyces cerevisiae S288C 46-50 3731110-9 1986 The high tumorigenic activity of 7MB[c]ACR 3,4-dihydrodiol in both tumor models suggests that a bay-region 3,4-diol-1,2-epoxide may be an ultimate carcinogenic metabolite of 7MB[c]ACR. Carbon 19-20 acrosin prepropeptide Mus musculus 39-42 16347047-1 1986 Mucor fragilis grown on bovine blood powder as the sole carbon source abundantly produced beta-N-acetylhexosaminidase. Carbon 56-62 beta-hexosaminidase subunit beta Bos taurus 90-117 3519679-0 1986 Defective suppression by insulin of leucine-carbon appearance and oxidation in type 1, insulin-dependent diabetes mellitus. Carbon 44-50 insulin Homo sapiens 25-32 3271870-4 1986 In addition, cytochrome P-450 preferentially oxidized the carbon to nitrogen bond of monoalkylhydrazines; this reaction resulted in the formation of aldehyde metabolites (via hydrazone intermediates). Carbon 58-64 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 13-29 16664671-2 1986 Viable seeds of wild type maize (Zea mays L.) as well as the mutant shrunken-2 (sh2) were found to mature when grown in culture with reducing sugars or sucrose as the carbon source. Carbon 167-173 glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic/amyloplastic Zea mays 68-78 16664671-2 1986 Viable seeds of wild type maize (Zea mays L.) as well as the mutant shrunken-2 (sh2) were found to mature when grown in culture with reducing sugars or sucrose as the carbon source. Carbon 167-173 glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic/amyloplastic Zea mays 80-83 16664671-3 1986 However, wild type and sh2 kernels had greater germination, starch content, and seed weight when sucrose, rather than reducing sugars, was the carbon source. Carbon 143-149 glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic/amyloplastic Zea mays 23-26 3007100-3 1985 The reactions of iron porphyrin--a model for cytochrome P-450--with various carbon-centered and peroxyl radicals generated by pulse radiolysis are examined. Carbon 76-82 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 45-61 3954771-0 1986 Inactivation of B12 and folate coenzymes by butyl nitrite as observed by NMR: implications on one-carbon transfer mechanism. Carbon 98-104 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 16-19 2418018-14 1986 Electron microscopy of rotary shadowed, carbon-coated replicas of TSP mAb complexes confirms the Ca2+ sensitivity of mAb binding and has been used to localize the epitopes for both mAbs on the three-dimensional structure of TSP. Carbon 40-46 thrombospondin 1 Homo sapiens 66-69 3739050-1 1986 Energy-filtered transmission electron microscopy (EFEM) was used to image the distributions of uranium and carbon in uranyl acetate stained catalase crystals. Carbon 107-113 catalase Homo sapiens 140-148 33874234-4 1985 The fungus readily utilizes the soluble protein bovine serum albumin (BSA) as sole nitrogen and carbon source, and produces lower yields on less soluble plant and animal proteins. Carbon 96-102 albumin Homo sapiens 55-68 4084506-5 1985 The positions of the C = N stretch in the deuterated pigment and the deuterated pigments regenerated with 11-cis-15-deuterioretinal or 11-cis-retinal containing 13C at carbon 15 are indicative that the Schiff-base linkage is protonated in rhodopsin, bathorhodopsin, and isorhodopsin. Carbon 21-22 rhodopsin Homo sapiens 239-248 3927906-1 1985 A cell-free human polymorphonuclear leukocyte preparation containing both 15- and 5-lipoxygenase activities was found to oxygenate phosphatidylcholine at carbon-15 of the arachidonic acid moiety. Carbon 154-160 arachidonate 15-lipoxygenase Homo sapiens 74-96 4044832-7 1985 The LTB4 omega-hydroxylase was inhibited significantly by carbon monoxide, ferricytochrome c, SKF-525A, and Triton X-100, but was not affected by alpha-naphthoflavone, azide, cyanide, catalase, and superoxide dismutase. Carbon 48-49 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 4-26 3891021-7 1985 Twitcher mice which were previously given colloidal carbon intravenously, had some Mac-1 positive cells which contained carbon particles both in the CNS and PNS. Carbon 52-58 integrin alpha M Mus musculus 83-88 4004905-8 1985 The other enzymatic rate constants are 0.016 min-1 for C(+)P(-), 0.74 min-1 for C(-)P(+) and 0.028 min-1 for C(-)P(-). Carbon 55-56 CD59 molecule (CD59 blood group) Homo sapiens 45-50 4004905-8 1985 The other enzymatic rate constants are 0.016 min-1 for C(+)P(-), 0.74 min-1 for C(-)P(+) and 0.028 min-1 for C(-)P(-). Carbon 55-56 CD59 molecule (CD59 blood group) Homo sapiens 70-75 4004905-8 1985 The other enzymatic rate constants are 0.016 min-1 for C(+)P(-), 0.74 min-1 for C(-)P(+) and 0.028 min-1 for C(-)P(-). Carbon 55-56 CD59 molecule (CD59 blood group) Homo sapiens 70-75 4053093-8 1985 These cleavage reactions might be attributed to SN2-like reactions on the acetal carbon atom and to base-induced eliminations, and they were enhanced by collision-induced dissociations. Carbon 81-87 solute carrier family 38 member 5 Homo sapiens 48-51 4004259-1 1985 Studies of the rates of aldehyde oxidase-mediated oxidation of iminium ion (I) and its specifically labeled counterpart containing deuterium at the methine and methylene carbons of its seven-membered ring (I-d3), are reported. Carbon 170-177 aldehyde oxidase 1 Homo sapiens 24-40 2985592-4 1985 The anomeric carbon region of the spectrum (approximately 90-105 ppm) of glycated cytochrome c was superimposable on that of N alpha-formyl-N epsilon-fructose-lysine, and contained three peaks characteristic of the alpha- and beta-furanose and beta-pyranose anomers of Amadori adducts to peripheral lysine residues on protein (pK alpha approximately 10.5). Carbon 13-19 cytochrome c, somatic Homo sapiens 82-94 3891021-7 1985 Twitcher mice which were previously given colloidal carbon intravenously, had some Mac-1 positive cells which contained carbon particles both in the CNS and PNS. Carbon 120-126 integrin alpha M Mus musculus 83-88 3921236-11 1985 Studies with space-filling models of the drugs the metabolism of which is associated with debrisoquine 4-hydroxylase in the literature indicated that all can be fitted to a general structure in which a basic nitrogen is about 5 A away from the site of carbon hydroxylation and a hydrophobic domain is near the site of hydroxylation. Carbon 252-258 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 90-116 3995008-5 1985 The distributions of carbon chain lengths for the saturated or 3-keto intermediates when acetoacetyl-labeled trypsinized enzyme is incubated with limiting malonyl coenzyme A or NADPH, respectively, show large fractions both of unreacted enzyme and of C16 or longer intermediates. Carbon 21-27 galectin 1B Gallus gallus 251-254 3997069-8 1985 Similar ligand specificity was also demonstrated in the binding study at 4 degrees C. The binding of 125I-m-AAT and c-AAT followed saturation kinetics with an apparent Kd of 1.3 X 10(-6) M and 1.7 X 10(-6) M, respectively. Carbon 18-19 glutamic-oxaloacetic transaminase 2 Rattus norvegicus 108-111 3997069-8 1985 Similar ligand specificity was also demonstrated in the binding study at 4 degrees C. The binding of 125I-m-AAT and c-AAT followed saturation kinetics with an apparent Kd of 1.3 X 10(-6) M and 1.7 X 10(-6) M, respectively. Carbon 18-19 glutamic-oxaloacetic transaminase 2 Rattus norvegicus 118-121 4036165-7 1985 The alkoxy chain length for optimal mono-oxygenase inhibition and complex formation with cytochrome P-450 appeared to be about five or six carbon atoms. Carbon 139-145 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 89-105 4000960-2 1985 The results show that despite distinct differences in structure and the glycosyl bond stability, the hydrolysis of wyosine proceeds via cleavage of the C-N bond by A-1 mechanism, analogously to simple nucleosides. Carbon 152-153 BCL2 related protein A1 Homo sapiens 164-167 3998237-8 1985 Milk fat from cows fed sunflower seed rations contained less carbon-14:0, 16:0, and 16:1 fatty acids but more carbon-18:0. Carbon 61-67 Weaning weight-maternal milk Bos taurus 0-4 3998237-8 1985 Milk fat from cows fed sunflower seed rations contained less carbon-14:0, 16:0, and 16:1 fatty acids but more carbon-18:0. Carbon 110-116 Weaning weight-maternal milk Bos taurus 0-4 12096754-6 1985 The complex with C10 (bisintercalator containing a 10-carbon atom linker chain) is slightly more stable than the C8 complex since its estimated binding site lifetime is 5-10 ms at 29 degrees C. Base pairs adjacent to the bound C10 are destabilized, relative to free d(AT)5.d(AT)5, but other base pairs in the C10 complex are little affected. Carbon 54-60 homeobox C10 Homo sapiens 17-20 2988200-1 1985 In the particles enriched with plasmatic membranes of target cells (human erythrocytes, skeletal muscles and adipocytes of rats) ATP was steadily formed within 1 min of incubation of the particles with insulin (4 microgram/ml) in the medium containing Tris-HCl buffer, pH 7.5, ADP, Mg2+, inorganic phosphate, NaF, during NADH oxidation in presence of cytochrome c and oxygen (30 degrees). Carbon 12-13 insulin Homo sapiens 202-209 4077872-8 1985 For example, on carbon, individual fibrinogen molecules retain their trinodular structure and adsorb randomly until a monolayer forms. Carbon 16-22 fibrinogen beta chain Homo sapiens 35-45 3977857-9 1985 These data implicate aspartate aminotransferase in the transfer of amino acid carbon and nitrogen from the mitochondria to the cytosol, and suggest that oxaloacetate, via phosphoenolpyruvate carboxykinase, can serve as an intermediate on the route of pyruvate formation for muscle alanine synthesis. Carbon 78-84 glutamic-oxaloacetic transaminase 2 Rattus norvegicus 21-47 3002335-4 1985 Compounds which contain heteroatoms at two adjacent carbon atoms such as alpha-amino acids, peptides, EDTA and o-phenanthroline are shown to inhibit the phosphatase reaction of glyceraldehyde-3-phosphate dehydrogenase. Carbon 52-58 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 177-217 6525177-1 1984 The idea that sp3 lone pairs of electrons on a heteroatom direct the departure of a leaving group from an adjacent tetrahedral carbon centre is shown to be untenable as a general principle, and the permissive evidence in favour of it to be accounted for by the principle of least nuclear motion. Carbon 127-133 Sp3 transcription factor Homo sapiens 14-17 3914938-4 1985 Primary metabolism involves hydroxylation of the alicyclic rings at several carbon atoms by cytochrome P-450-mediated monooxygenase. Carbon 76-82 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 92-108 6470514-6 1984 This and other features of the composition of the unsaturated fatty acids indicate that the delta 6-desaturase that produces the monounsaturated fatty acids of human sebum requires a substrate having a straight chain of at least 12 carbon atoms extending from the carboxyl group. Carbon 232-238 fatty acid desaturase 2 Homo sapiens 92-110 6440489-0 1984 Methene bridge carbon atom elimination in oxidative heme degradation catalyzed by heme oxygenase and NADPH-cytochrome P-450 reductase. Carbon 15-21 cytochrome p450 oxidoreductase Homo sapiens 101-133 6440489-2 1984 Biliverdin IX alpha is formed by elimination of one methene bridge carbon atom as CO. Purified NADPH-cytochrome P-450 reductase alone will also degrade heme but biliverdin is a minor product (15%). Carbon 67-73 cytochrome p450 oxidoreductase Homo sapiens 95-127 6592593-2 1984 The H atom on C-20 was in back next to C-18 in the crystal structures of both of the compounds, and C-22 was found to be cis-oriented ("left-handed") to C-13 in euphol and trans-oriented to it ("right-handed") in tirucallol. Carbon 14-15 Bardet-Biedl syndrome 9 Homo sapiens 39-43 6525029-0 1984 Conformational equilibria in flunitrazepam due to sp2-sp2 carbon-carbon single bond rotational isomerism. Carbon 58-64 Sp2 transcription factor Homo sapiens 50-53 6525029-0 1984 Conformational equilibria in flunitrazepam due to sp2-sp2 carbon-carbon single bond rotational isomerism. Carbon 58-64 Sp2 transcription factor Homo sapiens 54-57 6525029-0 1984 Conformational equilibria in flunitrazepam due to sp2-sp2 carbon-carbon single bond rotational isomerism. Carbon 65-71 Sp2 transcription factor Homo sapiens 50-53 6525029-0 1984 Conformational equilibria in flunitrazepam due to sp2-sp2 carbon-carbon single bond rotational isomerism. Carbon 65-71 Sp2 transcription factor Homo sapiens 54-57 24277281-1 1984 Compounds containing a terminal carbon-carbon triple bond, ranging in structure from the 17alpha-ethynyl substituted contraceptive steroids to acetylene gas, when administered to rats cause a selective and rapid time dependent loss of up to 50% of hepatic cytochrome P-450. Carbon 32-38 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 256-272 6542186-1 1984 The biological oxidation of several tributyltin derivatives, by a cytochrome P-450 dependent monooxygenase enzyme system with reduced nicotinamideadeninedinucleotidephosphate as the essential cofactor, produced carbon-hydroxylated compounds identified as alpha-, beta-, gamma- and delta-hydroxybutyldibutyltin derivatives. Carbon 211-217 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 66-82 24277281-1 1984 Compounds containing a terminal carbon-carbon triple bond, ranging in structure from the 17alpha-ethynyl substituted contraceptive steroids to acetylene gas, when administered to rats cause a selective and rapid time dependent loss of up to 50% of hepatic cytochrome P-450. Carbon 39-45 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 256-272 6698175-0 1984 Effect of carbon particles on the recovery of bone marrow stem cells after irradiation in LPS-resistant C3H/HeJ mice. Carbon 10-16 toll-like receptor 4 Mus musculus 90-93 6611155-1 1984 Deuterium labeling of 7-ethoxycoumarin on the carbon undergoing oxidation by cytochrome P-450 results in a redirection of metabolism from O-deethylation to ring hydroxylation at C6 (Harada, N. et al (1984) J Biol Chem 259, 3005-3010). Carbon 46-52 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 77-93 6427214-6 1984 In decreasing order of reactivity were the complexes with A-I, C-I, C-III-1, C-III-2, C-II, and A-II. Carbon 63-64 NLR family pyrin domain containing 3 Homo sapiens 96-100 6427214-6 1984 In decreasing order of reactivity were the complexes with A-I, C-I, C-III-1, C-III-2, C-II, and A-II. Carbon 68-69 NLR family pyrin domain containing 3 Homo sapiens 96-100 6430582-2 1984 The serum HDL2-C levels in the insulin-treated group were significantly higher than those in the normal group in which the total cholesterol (TC), triglyceride (TG), obesity index and age were matched whereas there was no difference between the serum HDL2-C levels in the oral agent-treated group or group treated by diet only and those in the normal group. Carbon 14-16 insulin Homo sapiens 31-38 6743275-14 1984 A mechanism for the metabolic activation of oct-1-yne is proposed, consisting in (a) microsomal hydroxylation of the carbon atom alpha to the acetylenic bond and (b) oxidation to yield octyn-3-one as the reactive species. Carbon 117-123 solute carrier family 22 member 1 Homo sapiens 44-49 6424574-1 1984 The activity of chymase was markedly inhibited by fatty acids with carbon chain lengths of 14-22 at doses greater than 0.02 microM, irrespective of the number of double bonds. Carbon 67-73 chymase 1 Homo sapiens 16-23 6698175-2 1984 Injection of carbon particles reduced damage and accelerated recovery of marrow hemopoietic stem cells, indicating that LPS-resistant mice can react normally to RES-blockade. Carbon 13-19 toll-like receptor 4 Mus musculus 120-123 6417145-3 1983 Freeze-dried, unstained human plasma fibronectin molecules deposited at pH 7.0-7.4 onto carbon films and examined by scanning transmission electron microscopy appeared relatively compact and pleiomorphic, with approximate average dimensions of 24 nm X 16 nm. Carbon 88-94 fibronectin 1 Homo sapiens 37-48 6708544-5 1984 In addition, spectral studies with rat adrenal mitochondria and a soluble preparation of human placental cytochrome P-450scc showed that binding of the 22-amine derivative to the enzyme produces difference spectra characteristic of nitrogen bonding to the heme; this indicates that the heme is positioned close to C-22 in the steroid-enzyme complex. Carbon 314-315 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 105-124 6417145-10 1983 We conclude that (a) the shape assumed by the fibronectin molecule can be strongly affected by solution conditions and by deposition onto certain surfaces; and that (b) the images of fibronectin seen by scanning transmission electron microscopy at neutral pH on carbon film are representative of molecules in physiologic solution. Carbon 262-268 fibronectin 1 Homo sapiens 46-57 6417145-10 1983 We conclude that (a) the shape assumed by the fibronectin molecule can be strongly affected by solution conditions and by deposition onto certain surfaces; and that (b) the images of fibronectin seen by scanning transmission electron microscopy at neutral pH on carbon film are representative of molecules in physiologic solution. Carbon 262-268 fibronectin 1 Homo sapiens 183-194 6643454-5 1983 With [2-13C] acetate as substrate, resonances and line splittings due to 13C-13C spin coupling of the C-2, C-3, and C-4 carbons of glutamate were well resolved. Carbon 120-127 complement C4A Rattus norvegicus 116-119 6619872-10 1983 The findings are interpreted in the context of the hypothesis that enzymes common to the malate-aspartate shuttle and the tricarboxylic acid cycle are physically complexed in brain, so that inhibition of aspartate aminotransferase, a component of the complex, impedes the flow of carbon through both metabolic pathways. Carbon 280-286 glutamic-oxaloacetic transaminase 2 Rattus norvegicus 204-230 6853506-3 1983 The 1/fT1p values of C-1 (1100 +/- 120 s-1) and C-2 (712 +/- 290 s-1) and the previously determined tau c (0.74 ns) yield Mn2+ to carbon distances of 5.7 +/- 0.3 and 6.1 +/- 0.5 A, respectively. Carbon 130-136 AKT interacting protein Homo sapiens 6-10 6139726-0 1983 Somatostatin stimulates clearance and hepatic uptake of colloidal carbon in the rat. Carbon 66-72 somatostatin Rattus norvegicus 0-12 6348555-3 1983 Conversely, growth on a non-fermentable carbon source such as ethanol or glycerol results in derepression of ADR2, and repression of ADC1. Carbon 40-46 alcohol dehydrogenase ADH1 Saccharomyces cerevisiae S288C 133-137 6223225-5 1983 Formation of mutagenic activity and of total organic halogen (TOX) is linearly related to humic concentration in the range of 0.2-1.6 mg/ml total organic carbon (TOC), and to chlorine concentration in the range of 0.1-1.0 chlorine equivalents per mole of carbon. Carbon 154-160 thymocyte selection-associated high mobility group box Rattus norvegicus 62-65 6223225-5 1983 Formation of mutagenic activity and of total organic halogen (TOX) is linearly related to humic concentration in the range of 0.2-1.6 mg/ml total organic carbon (TOC), and to chlorine concentration in the range of 0.1-1.0 chlorine equivalents per mole of carbon. Carbon 255-261 thymocyte selection-associated high mobility group box Rattus norvegicus 62-65 6687691-9 1983 In the second half of the C-propeptide, there was complete conservation of a 37 amino acid sequence and conservation of 50 out of 51 amino acids in the same region, an observation which suggested that the region serves some special purpose such as directing the association of one pro alpha 2(I) C-propeptide with two pro alpha 1(I) C-propeptides so as to produce the heteropolymeric structure of type I procollagen. Carbon 26-27 collagen type I alpha 2 chain Homo sapiens 397-415 6358796-6 1983 The PDC1 mRNA levels found in different mutants and in cells growing in media containing carbon sources other than glucose or ethanol suggest that the amount of PDC1 mRNA in yeast cells is affected by a number of different factors. Carbon 89-95 indolepyruvate decarboxylase 1 Saccharomyces cerevisiae S288C 4-8 6296095-5 1983 This indicates that oxygenation of the acid at C-5 occurred before the elimination of hydrogen and suggests that removal of the pro-S hydrogen at C-10 in 5-hydroperoxy-6,8,11,14,17-eicosapentaenoic acid initiates its transformation to trans-5(S),6(S)-oxido-7,9-trans-11,14,17-cis-eicosapentaenoic acid (leukotriene A5). Carbon 47-48 homeobox C10 Homo sapiens 146-150 6578391-10 1983 P24 from C-ALL cell spent medium was present in the 35-45% fraction of a saturated ammonium sulfate (SAS) partition of spent medium. Carbon 9-10 transmembrane p24 trafficking protein 2 Homo sapiens 0-3 6358796-6 1983 The PDC1 mRNA levels found in different mutants and in cells growing in media containing carbon sources other than glucose or ethanol suggest that the amount of PDC1 mRNA in yeast cells is affected by a number of different factors. Carbon 89-95 indolepyruvate decarboxylase 1 Saccharomyces cerevisiae S288C 161-165 6896331-0 1982 Identification of a new C-23 oxidation pathway of metabolism for 1,25-dihydroxyvitamin D3 present in intestine and kidney. Carbon 24-25 dopamine receptor D3 Gallus gallus 87-89 16662735-4 1982 The results indicate that inhibition of glutamine synthetase and thereby inhibition of photorespiratory nitrogen cycling restricts the sink capacity for glycolate in the photorespiratory carbon cycle. Carbon 187-193 glutamate-ammonia ligase Homo sapiens 40-60 6815172-1 1982 The exchange of glycine carboxyl carbon with CO2 catalyzed by the combination of chicken liver glycine decarboxylase (P-protein) and aminomethyl carrier protein (H-protein) was markedly inhibited by various divalent cations, although extents of inhibition by individual metal ions varied considerably. Carbon 33-39 glycine decarboxylase Gallus gallus 95-116 6815172-1 1982 The exchange of glycine carboxyl carbon with CO2 catalyzed by the combination of chicken liver glycine decarboxylase (P-protein) and aminomethyl carrier protein (H-protein) was markedly inhibited by various divalent cations, although extents of inhibition by individual metal ions varied considerably. Carbon 33-39 glycine cleavage system protein H Gallus gallus 162-171 6962833-2 1982 It was found that the binding ability with the ACM antisera was markedly decreased by the following structural changes in ACM: N,N-didemethylation of the rhodosamine moiety; 6-O- or 4-O-methylation; removal of the methoxycarbonyl group at C-10; hydroxylation at C-1, C-2 or C-11. Carbon 48-49 complement C2 Oryctolagus cuniculus 267-270 6962833-2 1982 It was found that the binding ability with the ACM antisera was markedly decreased by the following structural changes in ACM: N,N-didemethylation of the rhodosamine moiety; 6-O- or 4-O-methylation; removal of the methoxycarbonyl group at C-10; hydroxylation at C-1, C-2 or C-11. Carbon 123-124 complement C2 Oryctolagus cuniculus 267-270 6896331-1 1982 Evidence is presented for the existence of a new C-23 oxidation pathway for the metabolism of the hormonally active form of vitamin D3, namely 1 alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3). Carbon 49-50 dopamine receptor D3 Gallus gallus 132-134 6896331-1 1982 Evidence is presented for the existence of a new C-23 oxidation pathway for the metabolism of the hormonally active form of vitamin D3, namely 1 alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3). Carbon 49-50 dopamine receptor D3 Gallus gallus 171-173 6896331-9 1982 It is proposed that the newly discovered C-23 pathway for metabolism of 1,25(OH)2D3 by the target intestinal mucosa and kidney may play a prominent role under physiological conditions of controlling the tissue levels of this hormonally active form of vitamin D3. Carbon 41-42 dopamine receptor D3 Gallus gallus 81-83 7109856-7 1982 The triglyceride carbon number distribution of milk from the above species (with the exception of the Weddell seal) was determined by gas liquid chromatography and compared to that predicted by the 1-random-2-random-3-random fatty acid distribution hypothesis. Carbon 17-23 Weaning weight-maternal milk Bos taurus 47-51 6126183-1 1982 The membrane potential (DeltaPsi) and the pH gradient (DeltapH) across the membrane of the insulin-secretory granule were determined in studies in vitro from the uptake of the permeant anion thio[(14)C]cyanate or the permeant base [(14)C]methylamine. Carbon 200-201 insulin Homo sapiens 91-98 6801051-6 1982 Correlation of the structures of the five analogues with their activities indicates that the enzyme requires a syn orientation of the carbon-oxygen bonds about C-2 and C-3 for activity, which is optimized by an anti relationship between the hydroxyl groups at C-1 and C-2 of the cyclopentanetriol monophosphates. Carbon 134-140 complement C2 Oryctolagus cuniculus 160-171 6127053-5 1982 Since especially P17 is able to use a large number of different substrates at low concentrations, assessment of maximal colony counts of this organism by growth experiments in various types of tap water may give information about the concentrations of easily assimilable organic carbon. Carbon 279-285 family with sequence similarity 72 member B Homo sapiens 17-20 6801051-6 1982 Correlation of the structures of the five analogues with their activities indicates that the enzyme requires a syn orientation of the carbon-oxygen bonds about C-2 and C-3 for activity, which is optimized by an anti relationship between the hydroxyl groups at C-1 and C-2 of the cyclopentanetriol monophosphates. Carbon 134-140 complement C2 Oryctolagus cuniculus 260-271 6124097-2 1982 A number of trends which differentiate 5-lipoxygenase from cyclo-oxygenase were observed: (a) In general, the potency of the acetylenic acids to inhibit 5-lipoxygenase increased with the carbon chain length up to carbons. Carbon 187-193 arachidonate 5-lipoxygenase Homo sapiens 39-53 6124097-2 1982 A number of trends which differentiate 5-lipoxygenase from cyclo-oxygenase were observed: (a) In general, the potency of the acetylenic acids to inhibit 5-lipoxygenase increased with the carbon chain length up to carbons. Carbon 187-193 arachidonate 5-lipoxygenase Homo sapiens 153-167 6124097-2 1982 A number of trends which differentiate 5-lipoxygenase from cyclo-oxygenase were observed: (a) In general, the potency of the acetylenic acids to inhibit 5-lipoxygenase increased with the carbon chain length up to carbons. Carbon 213-220 arachidonate 5-lipoxygenase Homo sapiens 39-53 6808582-1 1982 A method was used which combines immunocytochemical techniques with surface replication by carbon films in order to localize fibronectin and N-acetyl-beta-hexosaminidase on cell surfaces of human fibroblasts in vitro. Carbon 91-97 fibronectin 1 Homo sapiens 125-136 6275815-5 1981 The short carbon chain paraffins with a high degree of chlorination increased the concentration of liver microsomal cytochrome P-450, inhibited the metabolism of 7-ethoxyresorufin but increased the metabolism of benzo(a)pyrene, especially the formation of the 4,5-diol metabolite. Carbon 10-16 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 116-132 7133987-3 1982 Calcium effects within the cell are mostly mediated through binding of the ion to low molecular weight proteins that form an evolutionary family including parvalbumin, calmodulin, troponin C, the alkali and regulatory light chains of myosin, the S-100 protein and the vitamin D-dependent intestinal calcium-binding protein. Carbon 0-1 calmodulin 1 Homo sapiens 168-178 7133987-3 1982 Calcium effects within the cell are mostly mediated through binding of the ion to low molecular weight proteins that form an evolutionary family including parvalbumin, calmodulin, troponin C, the alkali and regulatory light chains of myosin, the S-100 protein and the vitamin D-dependent intestinal calcium-binding protein. Carbon 0-1 S100 calcium binding protein B Homo sapiens 246-251 7030898-2 1981 The delta C-P correlated inversely with duration of diabetes (tau = -0.27, p less than 0.01) and daily insulin requirement (tau = -0.22, p less than 0.05) in the 50 IDDM studied of whom 28 exhibited a measurable delta C-P. Carbon 10-11 insulin Homo sapiens 103-110 6788083-6 1981 The large magnitude of these KIEs requires that carbon-oxygen bond scission be far advanced in the transition states for these reactions; therefore in the transition states for the first irreversible steps in these reaction sequences, scission of the glycosidic bond must be essentially complete for the reactions catalyzed by lysozyme and beta-glucosidase A, which are thought to proceed via SN1 and SN2 mechanisms, respectively. Carbon 48-54 solute carrier family 38 member 3 Homo sapiens 393-396 6456145-5 1981 The most effective inhibitors of rhodopsin regeneration were molecules whose structure could be superimposed on 9-cis or 11-cis retinal up to carbon atom 11. Carbon 142-148 rhodopsin Homo sapiens 33-42 6456145-8 1981 The most effective inhibitors were the all-trans C17-aldehyde (beta-ionylideneacetaldehyde) or C18-ketone (beta-ionylidenepent-3-ene-2-one) which, compared to retinal, lack two or three carbon atoms from the end of the poylene chain. Carbon 186-192 Bardet-Biedl syndrome 9 Homo sapiens 95-98 6794031-1 1981 The in vivo flux of carbon through the pentose shunt is investigated as a function of different 6-phosphogluconate dehydrogenase (6Pgd) and glucose-6-phosphate dehydrogenase (G6pd) genotypes by using differential radioactive labeling of the C-1 and C-6 positions of glucose. Carbon 20-26 Zwischenferment Drosophila melanogaster 140-173 6794031-1 1981 The in vivo flux of carbon through the pentose shunt is investigated as a function of different 6-phosphogluconate dehydrogenase (6Pgd) and glucose-6-phosphate dehydrogenase (G6pd) genotypes by using differential radioactive labeling of the C-1 and C-6 positions of glucose. Carbon 20-26 Zwischenferment Drosophila melanogaster 175-179 6794031-2 1981 Alternative 6Pgd-G6pd genotypes are shown to differ in relative in vivo carbon flux through the pentose shunt. Carbon 72-78 Zwischenferment Drosophila melanogaster 17-21 7240172-0 1981 Chemical and carbon-13 nuclear magnetic resonance studies of the blood group M and N active sialoglycopeptides from human glycophorin A. Carbon 13-19 glycophorin A (MNS blood group) Homo sapiens 122-135 6788083-6 1981 The large magnitude of these KIEs requires that carbon-oxygen bond scission be far advanced in the transition states for these reactions; therefore in the transition states for the first irreversible steps in these reaction sequences, scission of the glycosidic bond must be essentially complete for the reactions catalyzed by lysozyme and beta-glucosidase A, which are thought to proceed via SN1 and SN2 mechanisms, respectively. Carbon 48-54 solute carrier family 38 member 5 Homo sapiens 401-404 7205871-7 1981 These results establish that cathechols responsible for the production of the poison oak/ivy contact dermatitis in humans undergo a sequence of reactions in the presence of human serum albumin that lead to covalent attachment of the catechols to the protein via carbon-nitrogen bonds. Carbon 262-268 albumin Homo sapiens 179-192 7032741-4 1981 The product of this reaction is probably the same as that obtained from the metabolism of MAM by alcohol dehydrogenase, namely, an unstable aldehydic derivative which decomposes rapidly to carbonium ions. Carbon 189-198 aldo-keto reductase family 1 member A1 Rattus norvegicus 97-118 7008840-0 1981 Hydrogen-1 and carbon-13 nuclear magnetic resonance of the aromatic residues of fd coat protein. Carbon 15-21 golgi phosphoprotein 3 Homo sapiens 83-95 7035837-5 1981 This agreed with observations that hexokinase activities were like wild-type during growth on non-fermentable carbon sources in hex2 mutants. Carbon 110-116 protein phosphatase regulator REG1 Saccharomyces cerevisiae S288C 128-132 7432488-3 1980 In the belief that the key to biological Pb(II) methylation lies in methyl transfer to Pb(II) from a carbonium ion donor (for example, S-adenosylmethionine), we recently initiated chemical and biological studies on the reactions of CH3+ donors with neutral and anionic Pb(II) compounds. Carbon 101-110 submaxillary gland androgen regulated protein 3B Homo sapiens 41-47 7432488-3 1980 In the belief that the key to biological Pb(II) methylation lies in methyl transfer to Pb(II) from a carbonium ion donor (for example, S-adenosylmethionine), we recently initiated chemical and biological studies on the reactions of CH3+ donors with neutral and anionic Pb(II) compounds. Carbon 101-110 submaxillary gland androgen regulated protein 3B Homo sapiens 87-93 7432488-3 1980 In the belief that the key to biological Pb(II) methylation lies in methyl transfer to Pb(II) from a carbonium ion donor (for example, S-adenosylmethionine), we recently initiated chemical and biological studies on the reactions of CH3+ donors with neutral and anionic Pb(II) compounds. Carbon 101-110 submaxillary gland androgen regulated protein 3B Homo sapiens 87-93 6246663-1 1980 Effects of carbon monoxide, nitrogen, ferricytochrome c and p-hydroxymercuribenzoate were studied on cholesterol 7 alpha-hydroxylase activity of swine hepatic microsomes. Carbon 4-5 cytochrome P450 family 7 subfamily A member 1 Sus scrofa 101-132 7397450-5 1980 Thus the restriction imposed on the free rotation of the phenyl ring about the carbon-imino nitrogen bond by the introduction of two ortho substituents appears to result in increased agonist activity on the histamine H(2)-receptor. Carbon 79-85 histamine H2 receptor Cavia porcellus 207-230 16661286-10 1980 The apparent lack of cooperation between the mesophyll and bundle sheath cells may have been due to inadequate levels of NADP-malic enzyme required for shuttling carbon as CO(2) from the PEP carboxylase products to the Calvin cycle. Carbon 162-168 NADP-dependent malic enzyme Zea mays 121-138 7378190-2 1980 Our results showed that "sub-critical" concentrations of long carbon chains of saturated and unsaturated FFA potentiated the platelet aggregation induced by "critical" concentration of thrombin. Carbon 62-68 coagulation factor II, thrombin Homo sapiens 185-193 7378190-3 1980 However, we suggest that: a) exogenous long carbon chains of FFA could enhance the platelet membrane lipids and increase the ciclic Endoperoxides, Prostaglandins and Thromboxan A2 synthesis; b) exogenous long carbon chains of FFA could induce the platelets more "sensitive" to aggregating effect of "critical" concentrations of thrombin. Carbon 44-50 coagulation factor II, thrombin Homo sapiens 328-336 6778858-3 1980 In the exchange reaction of the carboxyl carbon of glycine wih CO2 catalyzed by the purified P-protein in the presence of H-protein, the pH optimum was 6.7, Km for glycine was 6.6 mM, and Km for H-protein was 7.4 microM. Carbon 41-47 OCA2 melanosomal transmembrane protein Rattus norvegicus 93-102 7400119-7 1980 The difference CD spectra of HSA in the presence and absence of T4 bound at the highest affinity site showed that the peak at 292 nm might be induced by an intrinsic dissymmetry owing to an asymmetric carbon atom in the T4 molecule, while a CD band at 325 nm might be due to perturbation of the beta-ring chromophore of T4 by certain intrinsic loci of HSA at the binding site. Carbon 201-207 albumin Homo sapiens 29-32 7400119-7 1980 The difference CD spectra of HSA in the presence and absence of T4 bound at the highest affinity site showed that the peak at 292 nm might be induced by an intrinsic dissymmetry owing to an asymmetric carbon atom in the T4 molecule, while a CD band at 325 nm might be due to perturbation of the beta-ring chromophore of T4 by certain intrinsic loci of HSA at the binding site. Carbon 201-207 albumin Homo sapiens 352-355 6244852-2 1980 Characteristic absorption bands of the solubilized crystals could be attributed to the cytochrome oxidase-cytochrome c complex with heme a:c ratio of 2:1. Carbon 5-6 cytochrome c, somatic Homo sapiens 106-118 7388122-3 1980 The application of our method to the rhodopsin/Meta II transition reveals signals which can tentatively be ascribed to the disappearance of the C = C-band of the protonated N-retinylidene Schiff base in rhodopsin. Carbon 144-145 rhodopsin Homo sapiens 37-46 7388122-3 1980 The application of our method to the rhodopsin/Meta II transition reveals signals which can tentatively be ascribed to the disappearance of the C = C-band of the protonated N-retinylidene Schiff base in rhodopsin. Carbon 144-145 rhodopsin Homo sapiens 203-212 7388122-3 1980 The application of our method to the rhodopsin/Meta II transition reveals signals which can tentatively be ascribed to the disappearance of the C = C-band of the protonated N-retinylidene Schiff base in rhodopsin. Carbon 148-149 rhodopsin Homo sapiens 37-46 7388122-3 1980 The application of our method to the rhodopsin/Meta II transition reveals signals which can tentatively be ascribed to the disappearance of the C = C-band of the protonated N-retinylidene Schiff base in rhodopsin. Carbon 148-149 rhodopsin Homo sapiens 203-212 6966256-1 1980 The influence of PSK, a protein bound polysaccharide from Coriolus versicolor on various immunological parameters was studied, PSK was found to enhance B cell activity as measured by the spleen plaque-forming cell assay in mice, and to stimulate mouse macrophages as determined by an enhancement of carbon clearance and an increase in the phagocytosis of opsonized sheep red blood cells by peritoneal mouse macrophages in vitro. Carbon 299-305 TAO kinase 2 Mus musculus 127-130 6898442-2 1980 The kinetic constants, kcat and Km, for the hydrolysis of these peptides revealed that this serine protease preferentially hydrolyzes peptides containing P1 amino acids which have medium to large hydrophobic side chains, except for those which are disubstituted on the first carbon of the side chain. Carbon 275-281 coagulation factor II, thrombin Homo sapiens 92-107 490561-4 1979 Incubation of all these analogues with chymotrypsin showed very little or no degradation up to 3 h. The results indicate that an increase in the chain length by one carbon atom in position 4 or 5 of angiotensin II increased resistance to degradation by chymotrypsin without any increase in in vivo duration of action. Carbon 165-171 angiotensinogen Rattus norvegicus 199-213 43143-10 1979 Carbon atoms C-2, C-3 and C-4 of the acetoacetate produced were derived from the carbon skeleton of the 4-methyl-2-oxopentanoate, but the acetoacetate carboxy group was derived from the incorporation of CO2. Carbon 81-87 complement C4A Rattus norvegicus 26-29 518847-1 1979 Proton and carbon-13 nuclear magnetic resonance (1H and 13C NMR) spectra of rhodopsin-phospholipid membrane vesicles and sonicated disk membranes are presented and discussed. Carbon 11-17 rhodopsin Homo sapiens 76-85 573135-9 1979 From the lecithins used pancreatic phospholipase A2 preferentially splits substrate molecules with nine carbon atoms in the acyl chain. Carbon 104-110 phospholipase A2 group IB Homo sapiens 35-51 37902-6 1979 Experiments on reconstituted vesicles containing internal (entrapped) cytochrome c indicate that turnover of enzyme oxidising entrapped cytochrome c in the presence of N,N,N",N"-tetramethyl-p-phenylenediamine or 2,3,5,6-tetramethyl-p-phenylendediamine is at a very much lower rate than enzyme oxidising external ferrocytochrome c. Carbon 17-18 cytochrome c, somatic Homo sapiens 70-82 37902-6 1979 Experiments on reconstituted vesicles containing internal (entrapped) cytochrome c indicate that turnover of enzyme oxidising entrapped cytochrome c in the presence of N,N,N",N"-tetramethyl-p-phenylenediamine or 2,3,5,6-tetramethyl-p-phenylendediamine is at a very much lower rate than enzyme oxidising external ferrocytochrome c. Carbon 17-18 cytochrome c, somatic Homo sapiens 136-148 28309616-0 1979 Carbon assimilation patterns and growth of the introduced CAM plant Opuntia inermis in Eastern Australia. Carbon 0-6 calmodulin 3 Homo sapiens 58-61 456423-5 1979 For example, the elongation of the L-ACPH structure by one carbon, or a change in the configuration of the amino group from L- to D-, caused a significant decrease in GABA inhibition. Carbon 59-65 acylaminoacyl-peptide hydrolase Homo sapiens 37-41 28309923-8 1978 It appears that the shift of the field curve to higher concentrations is caused by the imcomplete availability of the 50 mum particulate carbon fraction to the daphnids. Carbon 137-143 latexin Homo sapiens 121-124 642003-0 1978 Resonance Raman spectroscopy of chemically modified retinals: assigning the carbon--methyl vibrations in the resonance Raman spectrum of rhodopsin. Carbon 76-82 rhodopsin Homo sapiens 137-146 284349-3 1979 These effects show that the strength of the C=N bond and the degree of protonation of the Schiff base nitrogen are the same in bathorhodopsin, rhodopsin, and isorhodopsin. Carbon 44-45 rhodopsin Homo sapiens 132-141 723635-4 1978 In this report, we shall primarily examine the role of insulin, the hormone of carbon storage, in maintaining glucose homeostasis during a 24-hr period. Carbon 79-85 insulin Homo sapiens 55-62 999000-0 1976 Infrared spectrophotometric observations of the adsorption of fibrinogen from solution at optically transparent carbon film electrode surfaces. Carbon 112-118 fibrinogen beta chain Homo sapiens 62-72 16386053-0 1976 Stereochemical specificity at carbon-20 and -22 of hydroxylated cholesterols for side-chain cleavage by adrenocortical cytochrome P-450scc. Carbon 30-36 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 119-138 561741-0 1977 [Effect of carbon baths on blood pressure level of aldosterone, renin, minerals in the blood and catecholamines in the urine of patients with essential hypertension]. Carbon 11-17 renin Homo sapiens 64-69 836496-5 1977 The in vivo antagonistic activity of [1-sarcosine,8-O-methylthreonine]angiotensin II is reduced considerably by shortening the chain length by one carbon atom as is in V. Carbon 147-153 angiotensinogen Rattus norvegicus 70-84 836393-5 1977 In mitochondria, both NADH and NADPH are used and acetyl-CoA is the only donor of two-carbon-atoms unit. Carbon 86-92 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 Mus musculus 57-60 176191-0 1976 Letter: Hydride transfer from NADH models to sp3-hybridized carbon. Carbon 60-66 Sp3 transcription factor Homo sapiens 45-48 8458-3 1976 Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1). Carbon 159-165 CD59 molecule (CD59 blood group) Homo sapiens 122-127 8458-3 1976 Aminooxyacetate attacks the Schiff base linkage of the enzyme several times faster (k1 = 3700 M-1 min-1 and k2 = 1000 M-1 min-1) than it attacks the aldehydic carbon of free P-pyridoxal (k = 290 M-1 min-1). Carbon 159-165 CD59 molecule (CD59 blood group) Homo sapiens 122-127 932041-4 1976 The labeled glycine was incubated with D-amino acid oxidase, an enzyme which, in the catalysis of the conversion of glycine to glyoxylic acid, specifically removes the hydrogen in the S configuration at carbon atom 2 of glycine. Carbon 203-209 D-amino-acid oxidase Rattus norvegicus 39-59 8429-4 1976 Both dihydropteridine reductase and phenylalanine hydroxylase activities were found to be higher in cells adapted to a medium containing L-phenylalanine or L-tyrosine as the sole carbon source than in those grown in L-asparagine. Carbon 179-185 quinoid dihydropteridine reductase Homo sapiens 5-31 941178-7 1976 GLC determinations show that hydroxylation has occurred at C-4-C-6-C-2. Carbon 2-3 complement C2 Oryctolagus cuniculus 67-70 951870-10 1976 The 25 degrees C adsorption isotherms of fibrinogen obtained for both the glass and LTI-carbon powder adsorbents are not amenable to Langmuir type analysis but indicate multilayer sorption with a possible change in binding mechanism after the completion of the first sorbed monolayer. Carbon 88-94 fibrinogen beta chain Homo sapiens 41-51 1023892-7 1976 c - 60 out of 68 patients (88%) submitted to chemotherapy for advanced neoplasms show a close correlation between CEA response to the chemotherapy and clinical response (p less than 0.001). Carbon 0-1 CEA cell adhesion molecule 3 Homo sapiens 114-117 170263-2 1975 The stereochemistry at carbon 21 was established after cleaving the side chain and oxidizing the resulting two epimers of tritiated glycolate with glycolate oxidase of known (2-pro-S) stereospecificity. Carbon 23-29 hydroxyacid oxidase 2 Homo sapiens 147-164 1176433-1 1975 Mycobacterium convolutum strain NPA-1 can utilize n-propylamine (NPA), isopropylamine (IPA), and 1,3-propane diamine (PD) as sole source of carbon, nitrogen, and energy. Carbon 140-146 URB1 ribosome biogenesis homolog Homo sapiens 32-37 179287-8 1975 The reaction mixture contained either 14beta-ol-17-one or 17alpha-ol-14-one derivatives, since oxidation by hydroxysteroid oxidoreductase was limited to the hydroxyl group attached to a carbon atom having the S-configuration. Carbon 186-192 oxidoreductase Saccharomyces cerevisiae S288C 123-137 54032-6 1975 (3) AFP was found to be synthesized from late G1 phase to the end of the S phase for 9 hours in C-4 and 25 hours in A-1. Carbon 96-97 alpha fetoprotein Homo sapiens 4-7 807971-1 1975 The chlorinated hydrocarbons DDT and PCB"s (polychlorinated biphenyls), ubiquitous pollutants of the marine environment, have been observed to reduce the cell division rate of marine phytoplankton, thereby indirectly reducing the total photosynthetic carbon fixation in treated cultures. Carbon 21-27 pyruvate carboxylase Homo sapiens 37-40 1180218-2 1975 The carbon is desorbed with CS2 at dry ice temperature or with a thermal desorption technique. Carbon 4-10 chorionic somatomammotropin hormone 2 Homo sapiens 28-31 1151304-0 1975 The distribution of natural stable isotopes of carbon as a possible tool for the differentiation of samples of TNT. Carbon 47-53 chromosome 16 open reading frame 82 Homo sapiens 111-114 164885-2 1975 Carbon-13 spin-lattice relaxation times (T1) have been determined for the carbon in the octapeptide hormone [5-isoleucine]-angiotensin II in aqueous solution. Carbon 0-6 angiotensinogen Homo sapiens 123-137 164885-2 1975 Carbon-13 spin-lattice relaxation times (T1) have been determined for the carbon in the octapeptide hormone [5-isoleucine]-angiotensin II in aqueous solution. Carbon 74-80 angiotensinogen Homo sapiens 123-137 235426-11 1975 Provided the source of cytochrome P-450 was the same, the ratio between 11beta- and 18hydroxylation was constant under all conditions and was not significantly different in the presence of metopirone, carbon monoxide, cytochrome c or different steroids. Carbon 17-18 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 23-39 1167554-4 1975 Proportions of carbons 16:0, 16:1, 18:0, 18:1, 18:2, and trans-monoene fatty acids of the milk fat were (1) 30.31, 3.24, 10.15, 30.48, 2.59, 7.91; (2) 26.37; and (3) 26.30, 3.72, 10.56, 30.10, 2.96, 9.84. Carbon 15-22 Weaning weight-maternal milk Bos taurus 90-94 4474832-1 1974 Long-chain saturated fatty acids (C(13) to C(18)) and fatty alcohols (C(12) to C(18)) were well utilized by three different soil isolates of Cladosporium resinae as the sole carbon and energy sources in static liquid cultures. Carbon 174-180 Bardet-Biedl syndrome 9 Homo sapiens 79-84 4812443-4 1974 Insulin further stimulates the conversion of glucose carbons into CO(2), but not into glyceride-glycerol. Carbon 53-60 insulin Homo sapiens 0-7 24493083-0 1971 [Differences in the light-activation of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase and of ribulose-5-phosphate kinase between plants containing the Calvin and those containing the C4-dicarboxylic acid pathway of photosynthetic carbon reduction]. Carbon 240-246 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase Zea mays 40-95 5158898-2 1971 In epididymal adipose tissue synthesizing fatty acids from fructose in vitro, addition of insulin led to a moderate increase in fructose uptake, to a considerable increase in the flow of fructose carbon atoms to fatty acid, to a decrease in the steady-state concentration of lactate and pyruvate in the medium, and to net uptake of lactate and pyruvate from the medium. Carbon 196-202 insulin Homo sapiens 90-97 19396987-8 1974 (4) It is postulated that with pyruvate as substrate, recycling of carbon via pyruvate carboxylase, phosphoenolpyruvate carboxylase and pyruvate kinase (ATP: pyruvate phosphotransferase, EC 2.7.1.40) is an important, energy-requiring, mechanism for the transfer of the proportion of NADH not directly associated with gluconeogenesis. Carbon 67-73 pyruvate carboxylase Homo sapiens 78-98 4357878-0 1973 Cytochrome c: observation of numerous single-carbon sites of the reduced and oxidized species by means of natural-abundance 13C nuclear magnetic resonance spectroscopy. Carbon 45-51 cytochrome c, somatic Homo sapiens 0-12 17794201-2 1972 Reduced carbon in lower Onverwacht cherts (Theespruit formation) is anomalously heavy (the average value of delta(13)C(PDB) is -16.5 per mil). Carbon 8-14 PDB1 Homo sapiens 119-122 5275374-3 1970 This reaction can be formulated as an abstraction of hydrogen from the C-21-hydroxyl group to form a C-21-alkoxy radical, followed by a 1,5-H.shift from the C-16 atom and beta-scission of the C-16-alkoxy radical leading to the loss of a C(2) fragment (C-20 and C-21) with the formation of the double bond between C-16 and C-17. Carbon 71-72 TBL1X/Y related 1 Homo sapiens 101-105 5275374-3 1970 This reaction can be formulated as an abstraction of hydrogen from the C-21-hydroxyl group to form a C-21-alkoxy radical, followed by a 1,5-H.shift from the C-16 atom and beta-scission of the C-16-alkoxy radical leading to the loss of a C(2) fragment (C-20 and C-21) with the formation of the double bond between C-16 and C-17. Carbon 71-72 TBL1X/Y related 1 Homo sapiens 101-105 5275374-3 1970 This reaction can be formulated as an abstraction of hydrogen from the C-21-hydroxyl group to form a C-21-alkoxy radical, followed by a 1,5-H.shift from the C-16 atom and beta-scission of the C-16-alkoxy radical leading to the loss of a C(2) fragment (C-20 and C-21) with the formation of the double bond between C-16 and C-17. Carbon 101-102 TBL1X/Y related 1 Homo sapiens 71-75 13971355-0 1962 Transfer of carbon from formate to amino acids of milk protein in the intact cow. Carbon 12-18 casein beta Bos taurus 50-62 5773090-3 1969 Albumin was reacted in vitro with aspirin labeled with (14)carbon at the acetyl-1 or the carboxyl carbon. Carbon 59-65 albumin Homo sapiens 0-7 5773090-3 1969 Albumin was reacted in vitro with aspirin labeled with (14)carbon at the acetyl-1 or the carboxyl carbon. Carbon 98-104 albumin Homo sapiens 0-7 5714494-0 1968 [Action of fasting and insulin on the synthesis of fatty acids beginning with glucose specifically marked with carbon and hydrogen]. Carbon 111-117 insulin Homo sapiens 23-30 17781583-2 1970 Carbon detected in concentrations of 157 micrograms per gram had a delta(13)C per mil (PDB) value of + 20. Carbon 0-6 PDB1 Homo sapiens 87-90 17731763-2 1969 The solubilities at 25 degrees C of the normal C(9) (220 parts per billion) and C(10) (52 parts per billion) alkanes decrease with increasing carbon number. Carbon 142-148 homeobox C10 Homo sapiens 80-85 4295239-3 1968 The aerobic level of NAD-linked LDH of S. aureus remained constant and was independent of the carbon source. Carbon 94-100 AT695_RS04475 Staphylococcus aureus 32-35 4295239-4 1968 In contrast, the level of LDH produced in an anaerobic environment was variable and was dependent on the carbon source. Carbon 105-111 AT695_RS04475 Staphylococcus aureus 26-29 4295239-5 1968 Growth anaerobically on pyruvate, as the sole fermentable carbon source, resulted in a maximal level of LDH activity, a value about eightfold greater than the aerobic level. Carbon 58-64 AT695_RS04475 Staphylococcus aureus 104-107 33582332-0 2021 Light-absorption enhancement of black carbon in the Asian outflow inferred from airborne SP2 and in-situ measurements during KORUS-AQ. Carbon 38-44 Sp2 transcription factor Homo sapiens 89-92 13871326-0 1961 [The use of lysozyme in association with vitamins K and C]. Carbon 56-57 lysozyme Homo sapiens 12-20 33934792-0 2021 Fluorescence-infrared absorption dual-mode nanoprobes based on carbon dots@SiO2 nanorods for ultrasensitive and reliable detection of carcinoembryonic antigen. Carbon 63-69 CEA cell adhesion molecule 3 Homo sapiens 134-158 33555100-5 2021 EQCM measurements also show that the carbon structure, with the presence of sp2 carbons, affects the charge storage mechanism by favoring counter-ion adsorption on SLG electrode versus ion exchange mechanism in amorphous porous carbons. Carbon 37-43 Sp2 transcription factor Homo sapiens 76-79 33555100-5 2021 EQCM measurements also show that the carbon structure, with the presence of sp2 carbons, affects the charge storage mechanism by favoring counter-ion adsorption on SLG electrode versus ion exchange mechanism in amorphous porous carbons. Carbon 80-87 Sp2 transcription factor Homo sapiens 76-79 13140324-0 1954 Elution and displacement analysis of insulin and adrenocorticotropic peptides on pre-treated carbon. Carbon 93-99 insulin Homo sapiens 37-44 33545646-0 2021 A key role of inner-cation-pi interaction in adsorption of Pb(II) on carbon nanotubes: Experimental and DFT studies. Carbon 69-75 submaxillary gland androgen regulated protein 3B Homo sapiens 59-65 33910144-0 2021 Microwave regeneration of granular activated carbon saturated with PFAS. Carbon 45-51 phosphoribosylformylglycinamidine synthase Homo sapiens 67-71 33555100-5 2021 EQCM measurements also show that the carbon structure, with the presence of sp2 carbons, affects the charge storage mechanism by favoring counter-ion adsorption on SLG electrode versus ion exchange mechanism in amorphous porous carbons. Carbon 228-235 Sp2 transcription factor Homo sapiens 76-79 33910144-1 2021 This study investigated the regeneration of PFAS-saturated granular activated carbons (GACs) by microwave (MW) irradiation. Carbon 78-85 phosphoribosylformylglycinamidine synthase Homo sapiens 44-48 34048654-0 2021 Charge Transport in and Electroluminescence from sp3-Functionalized Carbon Nanotube Networks. Carbon 68-74 Sp3 transcription factor Homo sapiens 49-52 33740669-8 2021 Both XCom software and EGSnrc simulation code were used to obtain the theoretical calculations that are significantly important to be able to understand the shielding properties of impregnated activated carbons (AC1 and AC2) for gamma-rays. Carbon 203-210 adenylate cyclase 1 Homo sapiens 212-215 33740669-8 2021 Both XCom software and EGSnrc simulation code were used to obtain the theoretical calculations that are significantly important to be able to understand the shielding properties of impregnated activated carbons (AC1 and AC2) for gamma-rays. Carbon 203-210 adenylate cyclase 2 Homo sapiens 220-223 33740669-10 2021 The calculated data showed that impregnated activated carbons (AC1 and AC2) are very appropriate and consistent to be one of the candidates for shielding materials of gamma-rays. Carbon 54-61 adenylate cyclase 1 Homo sapiens 63-66 33740669-10 2021 The calculated data showed that impregnated activated carbons (AC1 and AC2) are very appropriate and consistent to be one of the candidates for shielding materials of gamma-rays. Carbon 54-61 adenylate cyclase 2 Homo sapiens 71-74 33215508-12 2021 Meanwhile, overexpression of duck TLR3 significantly promoted the transcription of IFN-beta, IRF7, TRIF, Mx, STAT1 and STAT2 mRNA after stimulation with poly(I:C). Carbon 160-162 TIR domain-containing adapter molecule 1 Anas platyrhynchos 99-103 33497733-7 2021 In ALV-J and poly(I:C) stimulated CEFs cells, the expression level of STAT1, IFN-alpha, IFN-beta, TLR3 and TLR7 were increased after IRF7 overexpressed, while the results were just the opposite after IRF7 interfered, which indicating that IRF7 may be associated with Toll-like receptor signaling pathway and JAK-STAT signaling pathway. Carbon 20-22 interferon alpha 1 Homo sapiens 77-86 33497733-7 2021 In ALV-J and poly(I:C) stimulated CEFs cells, the expression level of STAT1, IFN-alpha, IFN-beta, TLR3 and TLR7 were increased after IRF7 overexpressed, while the results were just the opposite after IRF7 interfered, which indicating that IRF7 may be associated with Toll-like receptor signaling pathway and JAK-STAT signaling pathway. Carbon 20-22 interferon alpha 1 Homo sapiens 88-96 33497733-7 2021 In ALV-J and poly(I:C) stimulated CEFs cells, the expression level of STAT1, IFN-alpha, IFN-beta, TLR3 and TLR7 were increased after IRF7 overexpressed, while the results were just the opposite after IRF7 interfered, which indicating that IRF7 may be associated with Toll-like receptor signaling pathway and JAK-STAT signaling pathway. Carbon 20-22 toll like receptor 7 Homo sapiens 107-111 33497733-7 2021 In ALV-J and poly(I:C) stimulated CEFs cells, the expression level of STAT1, IFN-alpha, IFN-beta, TLR3 and TLR7 were increased after IRF7 overexpressed, while the results were just the opposite after IRF7 interfered, which indicating that IRF7 may be associated with Toll-like receptor signaling pathway and JAK-STAT signaling pathway. Carbon 20-22 interferon regulatory factor 7 Homo sapiens 133-137 33497733-7 2021 In ALV-J and poly(I:C) stimulated CEFs cells, the expression level of STAT1, IFN-alpha, IFN-beta, TLR3 and TLR7 were increased after IRF7 overexpressed, while the results were just the opposite after IRF7 interfered, which indicating that IRF7 may be associated with Toll-like receptor signaling pathway and JAK-STAT signaling pathway. Carbon 20-22 interferon regulatory factor 7 Homo sapiens 200-204 33497733-7 2021 In ALV-J and poly(I:C) stimulated CEFs cells, the expression level of STAT1, IFN-alpha, IFN-beta, TLR3 and TLR7 were increased after IRF7 overexpressed, while the results were just the opposite after IRF7 interfered, which indicating that IRF7 may be associated with Toll-like receptor signaling pathway and JAK-STAT signaling pathway. Carbon 20-22 interferon regulatory factor 7 Homo sapiens 200-204 33740669-7 2021 In this article, we review the basics of the impregnated activated carbons (AC1 and AC2), as well as the link between the structural behaviors and the gamma shielding properties in terms of both quality and efficiency. Carbon 67-74 adenylate cyclase 1 Homo sapiens 76-79 34048654-1 2021 The controlled covalent functionalization of semiconducting single-walled carbon nanotubes (SWCNTs) with luminescent sp3 defects leads to additional narrow and tunable photoluminescence features in the near-infrared and even enables single-photon emission at room temperature, thus strongly expanding their application potential. Carbon 74-80 Sp3 transcription factor Homo sapiens 117-120 33684425-10 2021 In addition, a separate group of animals neonatally treated with saline or Poly I:C from P5-7 demonstrated increased TNFalpha protein levels in the hippocampus but not prefrontal cortex, verifying increased TNFalpha in the brain produced by Poly I:C. Carbon 82-83 tumor necrosis factor Rattus norvegicus 117-125 33684425-10 2021 In addition, a separate group of animals neonatally treated with saline or Poly I:C from P5-7 demonstrated increased TNFalpha protein levels in the hippocampus but not prefrontal cortex, verifying increased TNFalpha in the brain produced by Poly I:C. Carbon 82-83 tumor necrosis factor Rattus norvegicus 207-215 34015920-4 2021 Our results suggested that the phosphorus was substituted into carbon sites form P-N/P N bonds with four coordination, which contribute P 2p level donor states in the band gap to enhance light absorption and reduce charge separation. Carbon 63-69 peripheral myelin protein 2 Homo sapiens 136-140 34016779-1 2021 The quest for planar sp2-hybridized carbon allotropes other than graphene, such as graphenylene and biphenylene networks, has stimulated substantial research efforts because of the materials" predicted mechanical, electronic, and transport properties. Carbon 36-42 Sp2 transcription factor Homo sapiens 21-24 34016779-3 2021 We report the bottom-up growth of an ultraflat biphenylene network with periodically arranged four-, six-, and eight-membered rings of sp2-hybridized carbon atoms through an on-surface interpolymer dehydrofluorination (HF-zipping) reaction. Carbon 150-156 Sp2 transcription factor Homo sapiens 135-138 34014968-4 2021 The total mean carbon sequestered at the national level, considering the cumulative number of natural resource based activities, for the year 2017-18 was estimated to be 102 MtCO2. Carbon 15-21 mitochondrially encoded cytochrome c oxidase II Homo sapiens 174-179 34014968-5 2021 The annual mean carbon sequestration is projected to increase to about 132 MtCO2 by 2020 and 249 MtCO2 by 2030. Carbon 16-22 mitochondrially encoded cytochrome c oxidase II Homo sapiens 75-80 34014968-5 2021 The annual mean carbon sequestration is projected to increase to about 132 MtCO2 by 2020 and 249 MtCO2 by 2030. Carbon 16-22 mitochondrially encoded cytochrome c oxidase II Homo sapiens 97-102 34015802-4 2021 This reactivity provides a mechanistically alternative tactic for sp2 carbon-boron bond assembly where the elementary steps of transition-metal mediated C-H activation and reductive elimination from azine-organometallic intermediates are replaced with a direct, Minisci9-style, radical addition. Carbon 70-76 Sp2 transcription factor Homo sapiens 66-69 34014968-7 2021 The cumulative carbon sink created by drought proofing activities is projected to be 56 MtCO2 in 2020, 281 MtCO2 in 2025 and 561 MtCO2 in 2030. Carbon 15-21 mitochondrially encoded cytochrome c oxidase II Homo sapiens 88-93 34014968-7 2021 The cumulative carbon sink created by drought proofing activities is projected to be 56 MtCO2 in 2020, 281 MtCO2 in 2025 and 561 MtCO2 in 2030. Carbon 15-21 mitochondrially encoded cytochrome c oxidase II Homo sapiens 107-112 34014968-7 2021 The cumulative carbon sink created by drought proofing activities is projected to be 56 MtCO2 in 2020, 281 MtCO2 in 2025 and 561 MtCO2 in 2030. Carbon 15-21 mitochondrially encoded cytochrome c oxidase II Homo sapiens 107-112 33957045-3 2021 AoiQ represents the first biochemically reconstituted FDH that can halogenate an enolizable sp3-hybridized carbon atom. Carbon 107-113 Sp3 transcription factor Homo sapiens 92-95 34008940-1 2021 A dual-response (near-infrared, alternating magnetic field) multifunctional nanoplatform was developed based on urokinase plasminogen activators (uPA)-loaded metal-organic-framework (MOF)-derived carbon nanomaterials (referred to uPA@CFs below) for thrombolytic therapy. Carbon 196-202 plasminogen activator, urokinase Homo sapiens 112-144 34008940-1 2021 A dual-response (near-infrared, alternating magnetic field) multifunctional nanoplatform was developed based on urokinase plasminogen activators (uPA)-loaded metal-organic-framework (MOF)-derived carbon nanomaterials (referred to uPA@CFs below) for thrombolytic therapy. Carbon 196-202 plasminogen activator, urokinase Homo sapiens 146-149 34008940-1 2021 A dual-response (near-infrared, alternating magnetic field) multifunctional nanoplatform was developed based on urokinase plasminogen activators (uPA)-loaded metal-organic-framework (MOF)-derived carbon nanomaterials (referred to uPA@CFs below) for thrombolytic therapy. Carbon 196-202 plasminogen activator, urokinase Homo sapiens 230-233 33987977-0 2021 Metformin Carbon Dots for Promoting Periodontal Bone Regeneration via Activation of ERK/AMPK Pathway. Carbon 10-16 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 88-92 33714159-1 2021 An innovative label-free electrochemical aptasensing platform has been designed for detection of insulin using functionalized mesoporous silica thin-film (MSTF) coated on a glassy carbon electrode through the one-step electrochemically assisted self-assembly (EASA) method. Carbon 180-186 insulin Homo sapiens 97-104 34008404-0 2021 Stereospecific Iron-Catalyzed Carbon (sp2)-Carbon (sp2) Cross-Coupling of Aryllithium with Vinyl Halides. Carbon 30-36 Sp2 transcription factor Homo sapiens 38-41 34008404-0 2021 Stereospecific Iron-Catalyzed Carbon (sp2)-Carbon (sp2) Cross-Coupling of Aryllithium with Vinyl Halides. Carbon 30-36 Sp2 transcription factor Homo sapiens 51-54 33881025-0 2021 Cobalt encapsulated in bamboo-like N-doped carbon nanotubes for highly sensitive electroanalysis of Pb(II): enhancement based on adsorption and catalysis. Carbon 43-49 submaxillary gland androgen regulated protein 3B Homo sapiens 100-106 33881025-4 2021 The novel constructed Co/N-CNTs are used as a modifier on a bare glass carbon electrode for the electrochemical detection of Pb(ii). Carbon 71-77 submaxillary gland androgen regulated protein 3B Homo sapiens 125-131 33690769-1 2021 The selective and efficient C-H methylation of sp2 and sp3 carbon centres has become a powerful transformation in the synthetic toolbox. Carbon 59-65 Sp3 transcription factor Homo sapiens 55-58 33985525-3 2021 In this work, hollow carbon nanosphere modified with polyethylene glycol-graft-polyethylenimine (HPP) was elaborately synthesized. Carbon 21-27 familial progressive hyperpigmentation 1 Homo sapiens 97-100 34056000-10 2021 In the radical gastrectomy for distal gastric cancer, carbon nanoparticle laparoscopy was not only helpful for the localization of small tumors but also for the thorough dissection of lymph nodes after the surgery, and the postoperative adverse reactions of carbon nanoparticle laparoscopy were also less, which was of great significance for the improvement of intestinal flora and the reduction of serum levels of EGFR, IL-32, and gastrin 17 in gastric cancer patients. Carbon 54-60 epidermal growth factor receptor Homo sapiens 415-419 33980877-5 2021 We found that c-9, t-11-CLA diet-fed AD model mice significantly exhibited (1) a decrease in amyloid-beta protein (Abeta) levels in the hippocampus, (2) an increase in the number of microglia, and (3) an increase in the number of astrocytes expressing the anti-inflammatory cytokines, interleukin-10 and 19 (IL-10, IL-19), with no change in the total number of astrocytes. Carbon 14-15 interleukin 10 Mus musculus 308-313 33980877-5 2021 We found that c-9, t-11-CLA diet-fed AD model mice significantly exhibited (1) a decrease in amyloid-beta protein (Abeta) levels in the hippocampus, (2) an increase in the number of microglia, and (3) an increase in the number of astrocytes expressing the anti-inflammatory cytokines, interleukin-10 and 19 (IL-10, IL-19), with no change in the total number of astrocytes. Carbon 14-15 interleukin 19 Mus musculus 315-320 33970328-7 2021 Young"s modulus of carbon, silicon, germanium, and tin nanotubes are obtained as 1029, 159.82, 83.23, and 83.15 GPa, respectively, using the density functional theory. Carbon 19-25 glycophorin A (MNS blood group) Homo sapiens 112-115 33890963-0 2021 A carbon dot doped lanthanide coordination polymer nanocomposite as the ratiometric fluorescent probe for the sensitive detection of alkaline phosphatase activity. Carbon 2-8 alkaline phosphatase, placental Homo sapiens 133-153 33949617-0 2021 PEG-PEI-modified gated N-doped mesoporous carbon nanospheres for pH/NIR light-triggered drug release and cancer phototherapy. Carbon 42-48 NOC2 like nucleolar associated transcriptional repressor Homo sapiens 68-71 33947836-6 2021 KEGG function analysis of these genes revealed that they were mainly enriched in the HIF-1 signaling pathway, NOD-like receptor signaling pathway, central carbon metabolism in cancer, and PPAR signaling pathway. Carbon 155-161 hypoxia inducible factor 1 subunit alpha Homo sapiens 85-90 33965456-9 2021 In-silico molecular docking analysis showed that increasing the aliphatic carbon chain length facilitates binding to HDAC6 residues, which might be important for the inhibitory potential of HDAC6. Carbon 74-80 histone deacetylase 6 Homo sapiens 117-122 33965456-9 2021 In-silico molecular docking analysis showed that increasing the aliphatic carbon chain length facilitates binding to HDAC6 residues, which might be important for the inhibitory potential of HDAC6. Carbon 74-80 histone deacetylase 6 Homo sapiens 190-195 33904737-1 2021 A new class of cyclazine analogues with periphery reminiscent of an aza[10]annulene framework, tethered internally by an sp3 carbon, is presented. Carbon 125-131 Sp3 transcription factor Homo sapiens 121-124 33949586-1 2021 The transition-metal-aided stereoselective construction of sp3-carbon-rich heterocyclic scaffolds using strained-ring systems has received considerable attention in recent years due to the prominent presence of these scaffolds in myriad natural products, bioactive molecules, and pharmaceutical components. Carbon 63-69 Sp3 transcription factor Homo sapiens 59-62 34025187-9 2021 The chemical shift of carbon in NCS2 group for Compound 1 and 2 were found at 200.82 and 197.79 ppm. Carbon 22-28 cytosolic thiouridylase subunit 2 Homo sapiens 32-36 33938102-2 2021 Here we developed a modular in vitro platform for the continuous conversion of CO 2 into complex multi-carbon compounds, such as monoterpenes (C10), sesquiterpenes (C15) and polyketides. Carbon 103-109 homeobox C10 Homo sapiens 143-146 33934328-3 2021 By analyzing the accumulation of 26 intracellular metabolites and the expression of 90 genes related to central carbon metabolism and stress response, we confirmed that the process oscillation was attributed to intracellular metabolic oscillation with phase difference, and the expression of HXK1, HXT1,2,4 and PFK1 was significantly different from other genes in the Embden-Meyerhof-Parnas pathway, indicating that glucose transport and phosphorylation could be key nodes for regulating the intracellular metabolism under oscillatory conditions. Carbon 112-118 6-phosphofructokinase subunit alpha Saccharomyces cerevisiae S288C 311-315 33742144-8 2021 RESULTS: shRNA suppression of LDHA generated a time-dependent decrease in LDH activity with transient shifts in intracellular lactate levels, a decrease in carbon flux from pyruvate into lactate and compensatory shifts in metabolic flux in glycolysis and the Krebs cycle. Carbon 156-162 lactate dehydrogenase A Homo sapiens 30-34 33994363-9 2021 The LDH-A/B DKO transcripts reflect a flow of carbons away from glycolysis toward the production of acetyl-CoA. Carbon 46-53 lactate dehydrogenase A Homo sapiens 4-9 33946464-2 2021 A high temperature of RTA (300-700 C) was applied to graphene under an argon atmosphere to form defects on sp2 carbon lattices. Carbon 112-118 Sp2 transcription factor Homo sapiens 108-111 33861279-5 2021 For Boc-Met-enkephalin, we show that ZULF-TOCSY allows one to observe all expected cross-peaks between carbonyl carbons and alpha-CH protons, while the popular HMBC method provides insufficient information. Carbon 112-119 proopiomelanocortin Homo sapiens 8-22 33910904-5 2021 Observations and model results constrain the cumulative Southern Ocean sink over 1850-2100 to 158 +- 6 petagrams of carbon under the low-emissions scenario Shared Socioeconomic Pathway 1-2.6 (SSP1-2.6) and to 279 +- 14 petagrams of carbon under the high-emissions scenario SSP5-8.5. Carbon 116-122 SUMO specific peptidase 6 Homo sapiens 192-196 33922744-9 2021 The results of XPS spectroscopy showed that the contribution of sp3 hybridized carbon increases after etching. Carbon 79-85 Sp3 transcription factor Homo sapiens 64-67 33513281-1 2021 A fundamental and ubiquitous phenomenon in chemistry is the contraction of both C-H and C-C bonds as the carbon atoms involved vary, in s-p hybridization, along sp 3 to sp 2 to sp. Carbon 80-81 Sp3 transcription factor Homo sapiens 161-165 33513281-1 2021 A fundamental and ubiquitous phenomenon in chemistry is the contraction of both C-H and C-C bonds as the carbon atoms involved vary, in s-p hybridization, along sp 3 to sp 2 to sp. Carbon 80-81 Sp2 transcription factor Homo sapiens 170-174 33513281-1 2021 A fundamental and ubiquitous phenomenon in chemistry is the contraction of both C-H and C-C bonds as the carbon atoms involved vary, in s-p hybridization, along sp 3 to sp 2 to sp. Carbon 88-89 Sp3 transcription factor Homo sapiens 161-165 33513281-1 2021 A fundamental and ubiquitous phenomenon in chemistry is the contraction of both C-H and C-C bonds as the carbon atoms involved vary, in s-p hybridization, along sp 3 to sp 2 to sp. Carbon 88-89 Sp2 transcription factor Homo sapiens 170-174 33513281-1 2021 A fundamental and ubiquitous phenomenon in chemistry is the contraction of both C-H and C-C bonds as the carbon atoms involved vary, in s-p hybridization, along sp 3 to sp 2 to sp. Carbon 88-89 Sp3 transcription factor Homo sapiens 161-165 33513281-1 2021 A fundamental and ubiquitous phenomenon in chemistry is the contraction of both C-H and C-C bonds as the carbon atoms involved vary, in s-p hybridization, along sp 3 to sp 2 to sp. Carbon 88-89 Sp2 transcription factor Homo sapiens 170-174 33513281-1 2021 A fundamental and ubiquitous phenomenon in chemistry is the contraction of both C-H and C-C bonds as the carbon atoms involved vary, in s-p hybridization, along sp 3 to sp 2 to sp. Carbon 105-111 Sp3 transcription factor Homo sapiens 161-165 33513281-1 2021 A fundamental and ubiquitous phenomenon in chemistry is the contraction of both C-H and C-C bonds as the carbon atoms involved vary, in s-p hybridization, along sp 3 to sp 2 to sp. Carbon 105-111 Sp2 transcription factor Homo sapiens 170-174 33513281-4 2021 Instead, we establish that this structural trend is caused by a diminishing steric (Pauli) repulsion between substituents around the pertinent carbon atom, as the coordination number decreases along sp 3 to sp 2 to sp. Carbon 143-149 Sp3 transcription factor Homo sapiens 199-203 33513281-4 2021 Instead, we establish that this structural trend is caused by a diminishing steric (Pauli) repulsion between substituents around the pertinent carbon atom, as the coordination number decreases along sp 3 to sp 2 to sp. Carbon 143-149 Sp2 transcription factor Homo sapiens 208-212 34007509-1 2021 This work reveals the As(V) adsorption behaviors onto iron oxide (Fe3O4) nanoparticles modified activated carbon (AC), originally developed from biochar (BC), as a green adsorbent denoted by FAC. Carbon 106-112 FA complementation group C Homo sapiens 191-194 33968889-9 2021 Both X-rays and Carbon ions promoted the exposure of HMGB1, IL-10, and TGF-beta in a time-dependent manner. Carbon 16-22 interleukin 10 Mus musculus 60-65 33968889-11 2021 Besides, compared with X-rays, carbon ions increased the exposure of HMGB1 while relatively reduced the exposure levels of immunosuppressive factors IL-10 and TGF-beta. Carbon 31-37 interleukin 10 Mus musculus 149-154 33948363-5 2021 As to the mechanism, mass-spectrometric analysis indicated that the LHPP interacting proteins were mainly enriched in regulation of energy metabolism, including Carbon metabolism, Oxidative phosphorylation, and Glycolysis. Carbon 161-167 phospholysine phosphohistidine inorganic pyrophosphate phosphatase Homo sapiens 68-72 33829753-3 2021 Herein, we report an effective CO2RR electrocatalyst that features Ag single-atom coordinated with three nitrogen atoms (Ag1-N3) anchored on porous concave N-doped carbon (Ag1-N3/PCNC), which is identified by X-ray absorption spectroscopy. Carbon 164-170 thioredoxin domain containing 12 Homo sapiens 172-175 33863803-5 2021 Multidimensional analyses of 138 samples allowed us to classify the effects of insulin into three distinct expression responses: a common set was present in all three groups and included genes encoding several lipid/cholesterol biosynthesis enzymes; a set of obesity-attenuated genes linked to tissue remodelling and protein translation was selectively regulated in the two non-obese states and several post obesity-enriched genes encoding proteins involved in e.g. one carbon metabolism were only responsive to insulin in the women who had lost weight. Carbon 470-476 insulin Homo sapiens 79-86 33885083-5 2021 The analyses of structural properties and binding energies have shown that all carbon atoms are in sp3 hybridization in hydrogenated Me-graphene with strong and stable C-H bonds, resulting in a boat-like favorable conformation for fully-hydrogenated Me-graphene. Carbon 79-85 Sp3 transcription factor Homo sapiens 99-102 33919207-1 2021 Carbon nanomaterials are a group of materials characterized by sp2/sp3 carbon backbone which, combined with surface atoms and/or chemical groups, ensures peculiar physical chemical features for a wide range of applications. Carbon 0-6 Sp2 transcription factor Homo sapiens 63-66 33919207-1 2021 Carbon nanomaterials are a group of materials characterized by sp2/sp3 carbon backbone which, combined with surface atoms and/or chemical groups, ensures peculiar physical chemical features for a wide range of applications. Carbon 0-6 Sp3 transcription factor Homo sapiens 67-70 33919207-1 2021 Carbon nanomaterials are a group of materials characterized by sp2/sp3 carbon backbone which, combined with surface atoms and/or chemical groups, ensures peculiar physical chemical features for a wide range of applications. Carbon 71-77 Sp2 transcription factor Homo sapiens 63-66 33919207-1 2021 Carbon nanomaterials are a group of materials characterized by sp2/sp3 carbon backbone which, combined with surface atoms and/or chemical groups, ensures peculiar physical chemical features for a wide range of applications. Carbon 71-77 Sp3 transcription factor Homo sapiens 67-70 33876365-3 2021 Our energetic calculations show that OH additions to carbon-carbon double bonds of i-PME are more favorable reaction pathways than H-abstraction reactions from the various CH sites of the titled molecule. Carbon 53-59 cystatin B Homo sapiens 85-88 33876365-3 2021 Our energetic calculations show that OH additions to carbon-carbon double bonds of i-PME are more favorable reaction pathways than H-abstraction reactions from the various CH sites of the titled molecule. Carbon 60-66 cystatin B Homo sapiens 85-88 33875998-1 2021 The inaccuracy of the most widely used potentials in calculating the phonon transport of sp3 carbon materials hinders the use of molecular dynamics simulations for revealing the underlying mechanism of phonon transport in diamond and related materials. Carbon 93-99 Sp3 transcription factor Homo sapiens 89-92 33581204-0 2021 Efficacy of treated sodium alginate and activated carbon fibre for Pb(II) adsorption. Carbon 50-56 submaxillary gland androgen regulated protein 3B Homo sapiens 67-73 33877193-6 2021 The dimeric organolead hydride exhibits transfer of both hydride ligands to the carbon atom of CS2 to give a dithiol ligand [CH2S2]2- bridging both organolead units. Carbon 80-86 chorionic somatomammotropin hormone 2 Homo sapiens 95-98 33759524-6 2021 This work not only reports the discovery of an all-sp2-carbon supramolecular pi-organogelator with negative curvature but also demonstrates the power of three-dimensional electron crystallography for the structural determination of submicrometer-sized molecular alignment. Carbon 55-61 Sp2 transcription factor Homo sapiens 51-54 33784456-3 2021 Sanderson"s electronegativity equalization principle provides insight into the shortening of the C-H covalent bond lengths for both sp3- and sp2-hybridized carbon atoms. Carbon 156-162 Sp3 transcription factor Homo sapiens 132-135 33784456-3 2021 Sanderson"s electronegativity equalization principle provides insight into the shortening of the C-H covalent bond lengths for both sp3- and sp2-hybridized carbon atoms. Carbon 156-162 Sp2 transcription factor Homo sapiens 141-144 33784456-4 2021 To the best of our knowledge, this neutron diffraction study has revealed the largest extents of sp3 and sp2 C-H bond shrinkages with a 3-sigma rule being satisfied. Carbon 109-110 Sp2 transcription factor Homo sapiens 105-108 33997699-2 2021 Herein, we report the successful synthesis of N-doped porous carbon (abbreviated as NC) from straw waste through the Maillard reaction to activate sp3-sp2 conversion efficient for the simultaneous removal of chlortetracycline (CTC) and hexavalent chromium (Cr(VI)). Carbon 61-67 Sp3 transcription factor Homo sapiens 147-150 33924395-3 2021 QSAR analysis attributed the good correlation with different types of atoms like non-ring Carbons and Nitrogens, amide Nitrogen, sp2-hybridized Carbons, etc. Carbon 144-151 Sp2 transcription factor Homo sapiens 129-132 33997699-2 2021 Herein, we report the successful synthesis of N-doped porous carbon (abbreviated as NC) from straw waste through the Maillard reaction to activate sp3-sp2 conversion efficient for the simultaneous removal of chlortetracycline (CTC) and hexavalent chromium (Cr(VI)). Carbon 61-67 Sp2 transcription factor Homo sapiens 151-154 33965350-4 2021 That error is probably caused by a dysmetabolic signal from the foregut, stimulated by food, that limits entry of 2-carbon fragments into the tricarboxylic acid cycle, the accumulation of lactate and, in turn, increases in glucose and insulin. Carbon 116-122 insulin Homo sapiens 235-242 33838695-7 2021 CASE PRESENTATION: A 76-year-old Japanese man with ACC who was treated with carbon ion radiotherapy for a primary oropharynx tumor presented with three metastatic lesions in the lung. Carbon 76-82 amyloid beta precursor protein Homo sapiens 1-2 33838695-7 2021 CASE PRESENTATION: A 76-year-old Japanese man with ACC who was treated with carbon ion radiotherapy for a primary oropharynx tumor presented with three metastatic lesions in the lung. Carbon 76-82 amyloid beta precursor protein Homo sapiens 26-27 33897464-3 2021 Short-chain (<6 carbon) fatty acids target FFAR2/GPR43 and FFAR3/GPR41. Carbon 16-22 free fatty acid receptor 2 Homo sapiens 43-48 33897349-6 2021 RYR2 mutations were identified in five cases with BECTS, including one heterozygous frameshift mutation (c.14361dup/p.Arg4790Pro fs*6), two heterozygous missense mutations (c.2353G > A/p.Asp785Asn and c.8574G > A/p.Met2858Ile), and two pairs of compound heterozygous mutations (c.4652A > G/p.Asn1551Ser and c.11693T > C/p.Ile3898Thr, c.7469T > C/p.Val2490Ala and c.12770G > A/p.Arg4257Gln, respectively). Carbon 52-53 ryanodine receptor 2 Homo sapiens 0-4 33837208-0 2021 Synthetic control over the binding configuration of luminescent sp3-defects in single-walled carbon nanotubes. Carbon 93-99 Sp3 transcription factor Homo sapiens 64-67 33837208-1 2021 The controlled functionalization of single-walled carbon nanotubes with luminescent sp3-defects has created the potential to employ them as quantum-light sources in the near-infrared. Carbon 50-56 Sp3 transcription factor Homo sapiens 84-87 33897464-3 2021 Short-chain (<6 carbon) fatty acids target FFAR2/GPR43 and FFAR3/GPR41. Carbon 16-22 free fatty acid receptor 2 Homo sapiens 49-54 33897464-3 2021 Short-chain (<6 carbon) fatty acids target FFAR2/GPR43 and FFAR3/GPR41. Carbon 16-22 free fatty acid receptor 3 Homo sapiens 59-64 33897464-3 2021 Short-chain (<6 carbon) fatty acids target FFAR2/GPR43 and FFAR3/GPR41. Carbon 16-22 free fatty acid receptor 3 Homo sapiens 65-70 33656348-4 2021 It is noteworthy that the melting points and IDRs of these cocrystals exhibit an odd-even alternation with the carbon chain length of the acids. Carbon 111-117 odd-skipped related transcription factor 1 Homo sapiens 81-84 33592745-1 2021 A sandwich-type electrochemical immunosensor was developed for the detection of CEA where hollow magnetic silica coated nickel/carbon (Ni/C@SiO2) nanocomposites was used as an immobilized carrier and gold nanoparticle-coated PANI microsphere (CPS@PANI@Au) as electrochemical transducer. Carbon 127-133 CEA cell adhesion molecule 3 Homo sapiens 80-83 34040734-5 2021 The radical nature of the open-shell superatomic [Cu7Al6](Cp*)6 cluster 3 is reflected in its reactivity towards addition of one Cu core atom leading to the closed shell superatom [Cu8Al6](Cp*)6 (4), and as well by its ability to undergo sigma(C-H) and sigma(Si-H) activation reactions of C6H5CH3 (toluene) and (TMS)3SiH (TMS = tris(trimethylsilyl)). Carbon 50-51 PYD and CARD domain containing Homo sapiens 312-315 34040734-5 2021 The radical nature of the open-shell superatomic [Cu7Al6](Cp*)6 cluster 3 is reflected in its reactivity towards addition of one Cu core atom leading to the closed shell superatom [Cu8Al6](Cp*)6 (4), and as well by its ability to undergo sigma(C-H) and sigma(Si-H) activation reactions of C6H5CH3 (toluene) and (TMS)3SiH (TMS = tris(trimethylsilyl)). Carbon 50-51 PYD and CARD domain containing Homo sapiens 322-325 33476663-3 2021 One-carbon metabolism (OCM), a biochemical pathway that is influenced by folate and vitamin B12, facilitates the methylation of As. Carbon 4-10 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 92-95 32779379-0 2021 Exposure to environmental black carbon exacerbates nasal epithelial inflammation via the reactive oxygen species (ROS)-nucleotide-binding, oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3)-caspase-1-interleukin 1beta (IL-1beta) pathway. Carbon 32-38 NLR family pyrin domain containing 3 Homo sapiens 211-216 32779379-0 2021 Exposure to environmental black carbon exacerbates nasal epithelial inflammation via the reactive oxygen species (ROS)-nucleotide-binding, oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3)-caspase-1-interleukin 1beta (IL-1beta) pathway. Carbon 32-38 caspase 1 Homo sapiens 218-227 32779379-0 2021 Exposure to environmental black carbon exacerbates nasal epithelial inflammation via the reactive oxygen species (ROS)-nucleotide-binding, oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3)-caspase-1-interleukin 1beta (IL-1beta) pathway. Carbon 32-38 interleukin 1 beta Homo sapiens 228-245 33544162-0 2021 Novel voltammetric tumor necrosis factor-alpha (TNF-alpha) immunosensor based on gold nanoparticles involved in thiol-functionalized multi-walled carbon nanotubes and bimetallic Ni/Cu-MOFs. Carbon 146-152 tumor necrosis factor Homo sapiens 19-46 33544162-0 2021 Novel voltammetric tumor necrosis factor-alpha (TNF-alpha) immunosensor based on gold nanoparticles involved in thiol-functionalized multi-walled carbon nanotubes and bimetallic Ni/Cu-MOFs. Carbon 146-152 tumor necrosis factor Homo sapiens 48-57 33544162-4 2021 Herein, a novel, sensitive, and selective voltammetric TNF-alpha immunosensor was prepared by using gold nanoparticles involved in thiol-functionalized multi-walled carbon nanotubes (AuNPs/S-MWCNTs) as sensor platform and bimetallic Ni/Cu-MOFs as sensor amplification. Carbon 165-171 tumor necrosis factor Homo sapiens 55-64 33254052-1 2021 In this study, an ultra-sensitive and selective Thrombin biosensor with aptamer-recognition surface is introduced based on carbon nanocomposite. Carbon 123-129 coagulation factor II, thrombin Homo sapiens 48-56 33199105-2 2021 In this work, residue activated carbon (RAC) was successfully synthesized from catechol distillation residue by a simple activation process based on two steps. Carbon 32-38 AKT serine/threonine kinase 1 Homo sapiens 40-43 33500094-2 2021 TiH2, carbon and copper powders were used as starting materials in which In-Situ reaction between carbon and TiH2 occurs to form TiC nanoparticles. Carbon 6-12 RuvB like AAA ATPase 2 Homo sapiens 109-113 33500094-2 2021 TiH2, carbon and copper powders were used as starting materials in which In-Situ reaction between carbon and TiH2 occurs to form TiC nanoparticles. Carbon 98-104 RuvB like AAA ATPase 2 Homo sapiens 0-4 33705096-0 2021 Synergistic Effect of N-Doped sp2 Carbon and Porous Structure in Graphene Gels toward Selective Oxidation of C-H Bond. Carbon 34-40 Sp2 transcription factor Homo sapiens 30-33 33656034-5 2021 In this review we target sp, sp2 and sp3 carbon fluorination, chlorination, bromination and iodination reactions using electrolysis as a redox medium. Carbon 41-47 Sp3 transcription factor Homo sapiens 37-40 34027041-0 2021 Targeting one-carbon metabolism requires mTOR inhibition: a new therapeutic approach in osteosarcoma. Carbon 14-20 mechanistic target of rapamycin kinase Homo sapiens 41-45 33792148-0 2021 ROCK inhibitor attenuates carbon blacks-induced pulmonary fibrosis in mice via Rho/ROCK/NF-kappa B pathway. Carbon 26-32 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 88-98 33705096-0 2021 Synergistic Effect of N-Doped sp2 Carbon and Porous Structure in Graphene Gels toward Selective Oxidation of C-H Bond. Carbon 34-35 Sp2 transcription factor Homo sapiens 30-33 33656031-5 2021 At the same time, N-doped carbon in the Ge/NC-A microspheres can greatly improve the electrical conductivity and the structural stability. Carbon 26-32 CEA cell adhesion molecule 4 Homo sapiens 43-47 33470790-1 2021 Carbon nanothreads, which are one-dimensional sp3-rich polymers, combine high tensile strength with flexibility owing to subnanometer widths and diamond-like cores. Carbon 0-6 Sp3 transcription factor Homo sapiens 46-49 33470790-2 2021 These extended carbon solids are constructed through pressure-induced polymerization of sp2 molecules such as benzene. Carbon 15-21 Sp2 transcription factor Homo sapiens 88-91 33600164-1 2021 The functionalization of single-walled carbon nanotubes (SWCNTs) with luminescent sp3 defects has greatly improved their performance in applications such as quantum light sources and bioimaging. Carbon 39-45 Sp3 transcription factor Homo sapiens 82-85 33686862-3 2021 This complex undergoes intramolecular cyclization (C C into Sc-imidazolyl insertion) with exo-selectivity, generating a beta-all-carbon-substituted quaternary center in the polycyclic imidazole derivative. Carbon 129-135 amyloid beta precursor protein Homo sapiens 118-124 33689323-4 2021 In addition, the current protocol allowed to effortlessly introduce the sp3-gem-dibromide carbon adjacent to the sterically demanding spiroketal center. Carbon 90-96 Sp3 transcription factor Homo sapiens 72-75 33729711-7 2022 The effects of different carbon sources, such as glucose, N-acetylglucosamine (NAG), N-acetylgalactosamine (NAGA), and inulin, were compared with results showing that the optimal carbon sources for butyric acid production were NAG, a major component of mucin in the human intestine, and glucose. Carbon 179-185 alpha-N-acetylgalactosaminidase Homo sapiens 108-112 33656848-5 2021 Characterization by X-ray photoelectron and absorption spectroscopies indicated the occurrence of tribologically induced rehybridization of carbon-carbon bonds from sp3 to sp2. Carbon 140-146 Sp3 transcription factor Homo sapiens 165-168 33656848-5 2021 Characterization by X-ray photoelectron and absorption spectroscopies indicated the occurrence of tribologically induced rehybridization of carbon-carbon bonds from sp3 to sp2. Carbon 140-146 Sp2 transcription factor Homo sapiens 172-175 33656848-5 2021 Characterization by X-ray photoelectron and absorption spectroscopies indicated the occurrence of tribologically induced rehybridization of carbon-carbon bonds from sp3 to sp2. Carbon 147-153 Sp3 transcription factor Homo sapiens 165-168 33656848-5 2021 Characterization by X-ray photoelectron and absorption spectroscopies indicated the occurrence of tribologically induced rehybridization of carbon-carbon bonds from sp3 to sp2. Carbon 147-153 Sp2 transcription factor Homo sapiens 172-175 33656848-6 2021 This mechanically induced structural transformation coincided with the dissociative surface reaction between hydrogen (oxygen) gas molecules and sp2 carbon-carbon bonds that are highly strained, which results in the formation of carbon-hydrogen groups (carbonyl or ether groups together with silicon atoms having higher oxidation states). Carbon 149-155 Sp2 transcription factor Homo sapiens 145-148 33656848-6 2021 This mechanically induced structural transformation coincided with the dissociative surface reaction between hydrogen (oxygen) gas molecules and sp2 carbon-carbon bonds that are highly strained, which results in the formation of carbon-hydrogen groups (carbonyl or ether groups together with silicon atoms having higher oxidation states). Carbon 156-162 Sp2 transcription factor Homo sapiens 145-148 33656848-6 2021 This mechanically induced structural transformation coincided with the dissociative surface reaction between hydrogen (oxygen) gas molecules and sp2 carbon-carbon bonds that are highly strained, which results in the formation of carbon-hydrogen groups (carbonyl or ether groups together with silicon atoms having higher oxidation states). Carbon 156-162 Sp2 transcription factor Homo sapiens 145-148 33729711-7 2022 The effects of different carbon sources, such as glucose, N-acetylglucosamine (NAG), N-acetylgalactosamine (NAGA), and inulin, were compared with results showing that the optimal carbon sources for butyric acid production were NAG, a major component of mucin in the human intestine, and glucose. Carbon 179-185 N-acetyl-alpha-glucosaminidase Homo sapiens 108-111 33189326-4 2021 Raman spectrum elucidates the phonon contribution of ZnS and breathing mode of kappa-point phonons and sp2 bonds of carbon atoms of rGO. Carbon 116-122 Sp2 transcription factor Homo sapiens 103-106 33331111-0 2021 Self-Pillared Ultramicroporous Carbon Nanoplates for Selective Separation of CH4/N2. Carbon 31-37 chimerin 2 Homo sapiens 77-83 33223238-0 2021 Nitrogen and fluorine co-doped green fluorescence carbon dots as a label-free probe for determination of cytochrome c in serum and temperature sensing. Carbon 50-56 cytochrome c, somatic Homo sapiens 105-117 33721901-4 2021 Expression of DIN6 and DIN10, the carbon (C) starvation-responsive genes, was upregulated when nitrate was oversupplied under Pi starvation, which suggested that the plants recognized the oversupply of nitrate as C starvation stress because of the reduction in the C/N ratio. Carbon 34-40 glutamine-dependent asparagine synthase 1 Arabidopsis thaliana 14-18 33213923-4 2021 The addition of biosolids materials to the thick compost cover at rates higher than 100 t ha-1 significantly reduced C:N ratio of the substrates, available phosphorus, and some of the nutrient cations, while notably increasing inorganic carbon and the potential solubility of Ni and Cu. Carbon 117-118 Rho GTPase activating protein 45 Homo sapiens 90-94 33595573-3 2021 Here we demonstrate via a combined molecular beams and ab initio investigation that corannulene can be synthesized in the gas phase through the reactions of 7-fluoranthenyl (C16H9 ) and benzo[ghi]fluoranthen-5-yl (C18H9 ) radicals with acetylene (C2H2) mimicking conditions in carbon-rich circumstellar envelopes. Carbon 277-283 PAXIP1 associated glutamate rich protein 1 Homo sapiens 122-125 33694163-2 2021 Here, we report a two dimensional covalent organic frameworks (2D-COFs), poly (perylene-imide-benzoquinone) nanorod through in-situ condensation on flexible actuated carbon cloth (PPIBNR-FACC) to function as a light harvester material for highly selective radical-radical coupling to vinyl sulfides (i.e. C-S bond activation). Carbon 166-172 FA complementation group C Homo sapiens 187-191 33279288-5 2021 More importantly, 10c possessed improved drug-like properties compared to those of ETR with an increased Fsp3 (Fraction of sp3 carbon atoms) value. Carbon 127-133 Rho GTPase activating protein 9 Homo sapiens 18-21 33684901-2 2021 Herein, we developed IrP2 nanocrystals uniformly anchored in P,N-codoped carbon nanosheets (IrP2@PNC-NS) as highly active OER electrocatalysts. Carbon 73-79 iron responsive element binding protein 2 Homo sapiens 21-25 33684901-2 2021 Herein, we developed IrP2 nanocrystals uniformly anchored in P,N-codoped carbon nanosheets (IrP2@PNC-NS) as highly active OER electrocatalysts. Carbon 73-79 iron responsive element binding protein 2 Homo sapiens 92-96 33678722-0 2021 Cytochrome c/multi-walled carbon nanotubes modified glassy carbon electrode for the detection of streptomycin in pharmaceutical samples. Carbon 59-65 cytochrome c, somatic Homo sapiens 0-12 33243574-8 2021 The rate constants obtained for the degradation of MB by C-TiO2 and C-BiPO4 at 20 C were 9.739 x 10-7 mM min-1 and 1.111 x 10-7 mM min-1, respectively. Carbon 57-58 CD59 molecule (CD59 blood group) Homo sapiens 106-117 33307410-5 2021 On the other side, PMS adsorbed on SWCNT could be efficiently activated through accepting pi electron in the sp2 carbon matrix of SWCNT rather than the electrons at dangling bonds to generate OH radicals attributed to the strong interaction between PMS and SWCNT. Carbon 113-119 Sp2 transcription factor Homo sapiens 109-112 33662383-4 2021 Very long chain PUFAs (VLC-PUFAs,n-3, >= 28 carbons) are at the sn-1 of this PC molecular species and interact with rhodopsin. Carbon 44-51 rhodopsin Homo sapiens 116-125 33707435-2 2021 Here we show that in 2015, a large isotopic fractionation between DIC and POC, a DIC and N deficit in AMZ waters indicate the predominance of in situ dark carbon fixation by sulfur-driven autotrophic denitrification in addition to anammox. Carbon 155-161 solute carrier family 25 member 10 Homo sapiens 66-69 33280844-0 2021 Taguchi optimization design of diameter-controlled synthesis of multi walled carbon nanotubes for the adsorption of Pb(II) and Ni(II) from chemical industry wastewater. Carbon 77-83 submaxillary gland androgen regulated protein 3B Homo sapiens 116-122 33404454-6 2021 By analyzing the relative content of carbon bonds using the area of intensity of the Raman peaks and a simulation of crystal morphology, we suggest that the number of graphene surface layers would be monolayers in nanodiamonds, comprising two kinds of C-C bonds, one being sp3 bonds of diamond in the core and the other being sp2 bonds of graphene on the surface. Carbon 37-43 Sp3 transcription factor Homo sapiens 273-276 33404454-6 2021 By analyzing the relative content of carbon bonds using the area of intensity of the Raman peaks and a simulation of crystal morphology, we suggest that the number of graphene surface layers would be monolayers in nanodiamonds, comprising two kinds of C-C bonds, one being sp3 bonds of diamond in the core and the other being sp2 bonds of graphene on the surface. Carbon 37-43 Sp2 transcription factor Homo sapiens 326-329 33379006-1 2021 To promote the development of molecular imprinting technique in the separation and analysis of protein, novel bovine serum albumin (BSA) surface imprinted nitrogen-doped magnetic carbon nanotubes (N-MCNTs@MIPs) are developed by this paper. Carbon 179-185 albumin Homo sapiens 117-130 33641906-0 2021 Mesoporous silica coated carbon nanofibers reduce embryotoxicity via ERK and JNK pathways. Carbon 25-31 mitogen-activated protein kinase 1 Homo sapiens 69-72 33641906-0 2021 Mesoporous silica coated carbon nanofibers reduce embryotoxicity via ERK and JNK pathways. Carbon 25-31 mitogen-activated protein kinase 8 Homo sapiens 77-80 32772808-5 2021 Compared with untransformed plants, the atpA-overexpressing tobacco showed an increased resistance to B. cinerea, characterized by reduced disease incidence, defense-associated hypersensitive response (HR)-like reactions, balanced reactive oxygen species, alleviated damage to chloroplast ultra-structure of leaf cell, elevated levels of ATP content and cpATPase activity, enhanced expression of carbon metabolism-, photosynthesis-, and defense-related genes. Carbon 396-402 ATP synthase CF1 alpha chain Nicotiana tabacum 40-44 33229094-8 2021 Agricultural soils with lower contents of organic carbon exhibited higher adsorption capacities towards p-ASA/ROX, which indicates that soil minerals play a key role in the adsorption of phenylarsonic acid compounds while organic matter could have strong inhibitory effect. Carbon 50-56 MAX network transcriptional repressor Homo sapiens 104-113 33310569-0 2021 Adsorption of Pb(II) and Cd(II) by magnetic activated carbon and its mechanism. Carbon 54-60 submaxillary gland androgen regulated protein 3B Homo sapiens 14-20 33716999-1 2021 Non-rainfall moisture (fog, dew, and water vapor; NRM) is an important driver of plant litter decomposition in grasslands, where it can contribute significantly to terrestrial carbon cycling. Carbon 176-182 zinc finger protein, FOG family member 1 Homo sapiens 23-26 33577317-2 2021 The success of our approach rested on an early decision to apply chemical network analysis to identify the strategic bonds that needed to be forged, as well as the efficient construction of the carbon framework through iterative Csp2-Csp3 cross-coupling, followed by an intramolecular inverse-demand Diels-Alder cycloaddition. Carbon 194-200 regulator of calcineurin 2 Homo sapiens 229-233 33015997-3 2021 The resulting (P^N)arylgold(III)C(sp) complexes have enabled the first study of reductive elimination on (P^N)gold(III) systems demonstrating that C(sp 2 )-C(sp) bond formation occurs at higher rates than those reported for analogous phosphine-based monodentate systems. Carbon 32-33 U6 snRNA biogenesis phosphodiesterase 1 Homo sapiens 15-18 32077934-5 2021 We also show that the RyR2 N-terminus domain interacts with the C-terminal channel pore region in a Ca2+-independent manner. Carbon 64-65 ryanodine receptor 2 Homo sapiens 22-26 33015997-3 2021 The resulting (P^N)arylgold(III)C(sp) complexes have enabled the first study of reductive elimination on (P^N)gold(III) systems demonstrating that C(sp 2 )-C(sp) bond formation occurs at higher rates than those reported for analogous phosphine-based monodentate systems. Carbon 32-33 Sp2 transcription factor Homo sapiens 147-153 33603190-6 2021 Compared to TLR3 alone, binding affinity to poly (I:C) is further increased in TLR3-CLEC18A and TLR3-CLEC18A(S339R) complexes. Carbon 52-54 C-type lectin domain family 18, member A Mus musculus 84-91 33603190-6 2021 Compared to TLR3 alone, binding affinity to poly (I:C) is further increased in TLR3-CLEC18A and TLR3-CLEC18A(S339R) complexes. Carbon 52-54 C-type lectin domain family 18, member A Mus musculus 101-108 33854884-1 2021 Extraordinary properties and great application potentials of carbon nanotubes (CNT) and graphene fundamentally rely on their large-scale perfect sp2 structure. Carbon 61-67 Sp2 transcription factor Homo sapiens 145-148 33603190-5 2021 In this study, we further demonstrate that CLEC18A and its mutant CLEC18A(S339R) associate with TLR3 in endosome and bind poly (I:C) specifically. Carbon 43-44 C-type lectin domain family 18, member A Mus musculus 66-73 33565536-1 2021 To overcome the shuttle effect in lithium-sulfur (Li-S) batteries, an sp/sp2 hybridized all-carbon interlayer by coating graphene (Gra) and hydrogen-substituted graphdiyne (HsGDY) with a specific surface area as high as 2184 m2 g-1 on a cathode is designed and prepared. Carbon 92-98 Sp2 transcription factor Homo sapiens 73-76 33672069-4 2021 The ratio of the sp2 hybridization carbon and sp3 hybridization carbon in the hydrogenated Si-DLC films, sp2/(sp2 + sp3) ratio, increased rapidly from ~0.2 to ~0.5 for SR doses of less than 20 mA h. SR exposure significantly changed the local structure of carbon atoms near the surface of the hydrogenated Si-DLC film. Carbon 35-41 Sp2 transcription factor Homo sapiens 17-20 33674148-4 2021 This leads to insulin resistance and spares muscle protein, because being the main supplier of carbon for new glucose production. Carbon 95-101 insulin Homo sapiens 14-21 33080499-2 2021 In the resultant Ge@C-CMK composite, the unique lane-like pore structure that cooperates with the amorphous carbon surface can not only mitigate the volume expansion of germanium particles, but also improve the electrical conductivity of germanium as well as facilitate Na+/K+ diffusion. Carbon 108-114 C-X-C motif chemokine ligand 9 Homo sapiens 22-25 33672069-4 2021 The ratio of the sp2 hybridization carbon and sp3 hybridization carbon in the hydrogenated Si-DLC films, sp2/(sp2 + sp3) ratio, increased rapidly from ~0.2 to ~0.5 for SR doses of less than 20 mA h. SR exposure significantly changed the local structure of carbon atoms near the surface of the hydrogenated Si-DLC film. Carbon 64-70 Sp3 transcription factor Homo sapiens 46-49 33672069-4 2021 The ratio of the sp2 hybridization carbon and sp3 hybridization carbon in the hydrogenated Si-DLC films, sp2/(sp2 + sp3) ratio, increased rapidly from ~0.2 to ~0.5 for SR doses of less than 20 mA h. SR exposure significantly changed the local structure of carbon atoms near the surface of the hydrogenated Si-DLC film. Carbon 64-70 Sp2 transcription factor Homo sapiens 105-108 33672069-4 2021 The ratio of the sp2 hybridization carbon and sp3 hybridization carbon in the hydrogenated Si-DLC films, sp2/(sp2 + sp3) ratio, increased rapidly from ~0.2 to ~0.5 for SR doses of less than 20 mA h. SR exposure significantly changed the local structure of carbon atoms near the surface of the hydrogenated Si-DLC film. Carbon 64-70 Sp2 transcription factor Homo sapiens 105-108 33387951-7 2021 The linear models revealed that the amount of dissolved organic carbon and of the water-soluble ions in rain samples, Ca2+, SO42-, NO3-, increases with the volume swept by the falling drops. Carbon 64-70 NBL1, DAN family BMP antagonist Homo sapiens 131-134 33672069-4 2021 The ratio of the sp2 hybridization carbon and sp3 hybridization carbon in the hydrogenated Si-DLC films, sp2/(sp2 + sp3) ratio, increased rapidly from ~0.2 to ~0.5 for SR doses of less than 20 mA h. SR exposure significantly changed the local structure of carbon atoms near the surface of the hydrogenated Si-DLC film. Carbon 64-70 Sp3 transcription factor Homo sapiens 46-49 33672069-4 2021 The ratio of the sp2 hybridization carbon and sp3 hybridization carbon in the hydrogenated Si-DLC films, sp2/(sp2 + sp3) ratio, increased rapidly from ~0.2 to ~0.5 for SR doses of less than 20 mA h. SR exposure significantly changed the local structure of carbon atoms near the surface of the hydrogenated Si-DLC film. Carbon 64-70 Sp2 transcription factor Homo sapiens 105-108 33672069-4 2021 The ratio of the sp2 hybridization carbon and sp3 hybridization carbon in the hydrogenated Si-DLC films, sp2/(sp2 + sp3) ratio, increased rapidly from ~0.2 to ~0.5 for SR doses of less than 20 mA h. SR exposure significantly changed the local structure of carbon atoms near the surface of the hydrogenated Si-DLC film. Carbon 64-70 Sp2 transcription factor Homo sapiens 105-108 33522533-3 2021 Here, by means of first-principles calculation, we report our newly discovered carbon monolayer 123-E8Y24-1 with robust Dirac nodal line states, which possesses a tetragonal lattice with P4/mmm symmetry and contains 8 sp2 carbon atoms (graphene: E8) and 24 sp carbon atoms (grapheyne: Y24) in the crystalline cell. Carbon 79-85 Sp2 transcription factor Homo sapiens 218-221 33522533-3 2021 Here, by means of first-principles calculation, we report our newly discovered carbon monolayer 123-E8Y24-1 with robust Dirac nodal line states, which possesses a tetragonal lattice with P4/mmm symmetry and contains 8 sp2 carbon atoms (graphene: E8) and 24 sp carbon atoms (grapheyne: Y24) in the crystalline cell. Carbon 222-228 Sp2 transcription factor Homo sapiens 218-221 33522533-3 2021 Here, by means of first-principles calculation, we report our newly discovered carbon monolayer 123-E8Y24-1 with robust Dirac nodal line states, which possesses a tetragonal lattice with P4/mmm symmetry and contains 8 sp2 carbon atoms (graphene: E8) and 24 sp carbon atoms (grapheyne: Y24) in the crystalline cell. Carbon 222-228 Sp2 transcription factor Homo sapiens 218-221 33438711-1 2021 An unprecedented Ru(ii)-catalyzed Csp2-H bond activation and annulation reaction of phenylindazolones with diaryl-substituted alkynes and dialkyl-substituted alkynes provided efficient routes for the construction of all-carbon quaternary-centered indolo[1,2-a]quinazolinones and quaternary carbon-centered indazolo[1,2-a]indazolones, respectively. Carbon 220-226 regulator of calcineurin 2 Homo sapiens 34-38 33438711-1 2021 An unprecedented Ru(ii)-catalyzed Csp2-H bond activation and annulation reaction of phenylindazolones with diaryl-substituted alkynes and dialkyl-substituted alkynes provided efficient routes for the construction of all-carbon quaternary-centered indolo[1,2-a]quinazolinones and quaternary carbon-centered indazolo[1,2-a]indazolones, respectively. Carbon 290-296 regulator of calcineurin 2 Homo sapiens 34-38 33708393-3 2021 Based on this, herein alpha,omega-alkanedi-carb-oxy-lic acids (DAn, where n represents the number of carbon atoms in the molecule, n = 2-6, 8-11) were designed as homologous additives to interfere with the self-assembly of pimelic acid (DA7) to further induce the form II compound, which differs from form I only in conformation. Carbon 101-107 NBL1, DAN family BMP antagonist Homo sapiens 63-66 33507752-2 2021 Specifically, the presence of chemisorbed hydrogen atoms forming an sp3-hybridized C-H bond is known to increase the reactivity of neighboring carbon atoms toward additional hydrogenation with wide-ranging applications from materials science to astrochemistry. Carbon 143-149 Sp3 transcription factor Homo sapiens 68-71 33502182-3 2021 Here, we demonstrate a bottom-up synthesis of three novel nanographenes (1-3) with well-defined defects in which seven-five-seven (7-5-7)-membered rings were introduced to their sp2 carbon frameworks. Carbon 182-188 Sp2 transcription factor Homo sapiens 178-181 33567275-0 2021 Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation. Carbon 16-22 T cell immunoglobulin and mucin domain containing 4 Mus musculus 0-4 33567275-4 2021 Here, we identify by a targeted screening of phagocyte receptors the phosphatidylserine receptors T cell immunoglobulin mucin 4 (Tim4) and Tim1 as the pattern-recognition receptors for carbon crystals. Carbon 185-191 T cell immunoglobulin and mucin domain containing 4 Mus musculus 98-127 33567275-4 2021 Here, we identify by a targeted screening of phagocyte receptors the phosphatidylserine receptors T cell immunoglobulin mucin 4 (Tim4) and Tim1 as the pattern-recognition receptors for carbon crystals. Carbon 185-191 T cell immunoglobulin and mucin domain containing 4 Mus musculus 129-133 33567275-4 2021 Here, we identify by a targeted screening of phagocyte receptors the phosphatidylserine receptors T cell immunoglobulin mucin 4 (Tim4) and Tim1 as the pattern-recognition receptors for carbon crystals. Carbon 185-191 hepatitis A virus cellular receptor 1 Mus musculus 139-143 33567275-5 2021 Docking simulation studies reveal spatiotemporally stable interfaces between aromatic residues in the extracellular IgV domain of Tim4 and one-dimensional carbon crystals. Carbon 155-161 T cell immunoglobulin and mucin domain containing 4 Mus musculus 130-134 33561155-4 2021 Since the chlorine atoms present in bisphenol C (BPC) exist in a pi-pi conjugated system due to the presence of an adjacent C = C double bond, we intended to prove that BPC is also a bifunctional ERalpha-agonist and ERbeta-antagonist exhibiting greatly enhanced agonist/antagonist activities. Carbon 46-47 estrogen receptor 1 Homo sapiens 196-203 33561155-4 2021 Since the chlorine atoms present in bisphenol C (BPC) exist in a pi-pi conjugated system due to the presence of an adjacent C = C double bond, we intended to prove that BPC is also a bifunctional ERalpha-agonist and ERbeta-antagonist exhibiting greatly enhanced agonist/antagonist activities. Carbon 46-47 estrogen receptor 1 Homo sapiens 216-222 33561155-4 2021 Since the chlorine atoms present in bisphenol C (BPC) exist in a pi-pi conjugated system due to the presence of an adjacent C = C double bond, we intended to prove that BPC is also a bifunctional ERalpha-agonist and ERbeta-antagonist exhibiting greatly enhanced agonist/antagonist activities. Carbon 51-52 estrogen receptor 1 Homo sapiens 196-203 33561155-4 2021 Since the chlorine atoms present in bisphenol C (BPC) exist in a pi-pi conjugated system due to the presence of an adjacent C = C double bond, we intended to prove that BPC is also a bifunctional ERalpha-agonist and ERbeta-antagonist exhibiting greatly enhanced agonist/antagonist activities. Carbon 51-52 estrogen receptor 1 Homo sapiens 216-222 32795825-7 2021 The synergies between the sp2-hybridized carbon surface and the active sites (such as phenolic OH and defects) facilitated the oxidation of 1-NA on graphite. Carbon 41-47 Sp2 transcription factor Homo sapiens 26-29 33421954-8 2021 Additionally, the flexible C-17-side-chain with appropriate hydroxy groups is considered to be important for the inhibitory activity of apotirucallane against hCES2. Carbon 27-28 carboxylesterase 2 Homo sapiens 159-164 33582801-0 2021 Genome-wide analysis in response to nitrogen and carbon identifies regulators for root AtNRT2 transporters. Carbon 49-55 nitrate transporter 2:1 Arabidopsis thaliana 87-93 33557113-3 2021 Therefore, in the present study, we examined the effect of MIA induced by polyinosinic:polycytidylic acid (Poly I:C) on the CX3CL1-CX3CR1 and CD200-CD200R axes, microglial trajectory (MhcII, Cd40, iNos, Il-1beta, Tnf-alpha, Il-6, Arg1, Igf-1, Tgf-beta and Il-4), and schizophrenia-like behaviour in adult male offspring of Sprague-Dawley rats. Carbon 114-115 C-X3-C motif chemokine ligand 1 Rattus norvegicus 124-130 33475637-0 2021 A new two-dimensional all-sp3 carbon allotrope with an indirect band gap and superior carrier mobility. Carbon 30-36 Sp3 transcription factor Homo sapiens 26-29 33475637-2 2021 However, there are only very few reported structures for stable 2D all-sp3 carbon allotropes. Carbon 75-81 Sp3 transcription factor Homo sapiens 71-74 33475637-3 2021 Here, we proposed a new 2D all-sp3 carbon allotrope, named as TTH-carbon. Carbon 35-41 Sp3 transcription factor Homo sapiens 31-34 33475637-3 2021 Here, we proposed a new 2D all-sp3 carbon allotrope, named as TTH-carbon. Carbon 66-72 Sp3 transcription factor Homo sapiens 31-34 33475637-9 2021 The proposed structure richens the 2D all-sp3 carbon allotropes and its properties make it a promising material for nanoelectronic and photoelectronic devices. Carbon 46-52 Sp3 transcription factor Homo sapiens 42-45 33475642-2 2021 Tetraethyl orthosilicate (TEOS) and resorcinol/formaldehyde (RF) assemble upon dictation by Ag+ and pyridyl-functionalized surfactants, producing porous carbon tubes (RF1) with a high surface area of 696 m2 g-1 and accessible mesopores ~15 nm in size. Carbon 153-159 mitochondrial translation release factor 1 Homo sapiens 167-170 33242714-2 2021 A biosensing event occurred when a hairpin target probe recognized miR-196b as a result of the opening of an electrode hairpin probe on a polydopmine-gold (PDA-Au) composite-modified screen-printed carbon electrode. Carbon 198-204 microRNA 196b Homo sapiens 67-75 33086215-3 2021 Here we report a gold nanoparticles-hosted mesoporous nitrogen doped carbon matrix, which is prepared using bovine serum albumin (BSA) through calcination. Carbon 69-75 albumin Homo sapiens 115-128 33086215-5 2021 Gold nanoparticles at N-doped bovine serum albumin carbon (AuNPs@NBSAC)-modified three-electrode strip-based flexible sensor system has been developed, which displayed effective, sensitive and selective for simultaneous detection of uric acid (UA) and dopamine (DA). Carbon 51-57 albumin Homo sapiens 37-50 33474940-1 2021 In a specifically designed molecular structure, two sp2-hybridized carbon atoms align their unhybridized 2pz orbitals in the same orientation to form an extremely long C2pz-C2pz sigma-single bond that goes beyond 3 A in length. Carbon 67-73 Sp2 transcription factor Homo sapiens 52-55 33007334-5 2021 Moreover, the IFP35 gene was significantly induced in vivo for 120 h following the infection of infectious spleen and kidney necrosis virus (ISKNV), and its mRNA and protein level was also significantly induced in vitro following the treatment of poly I:C, IFNh, IFNc, as well as IFN-gamma. Carbon 254-255 interferon induced protein 35 Homo sapiens 14-19 33559290-5 2021 Furthermore, the oxidative esterification involving SP3 C-H bond functionalization is also demonstrated using the same catalyst. Carbon 56-57 Sp3 transcription factor Homo sapiens 52-55 33183429-5 2021 The results of this study show that thyroid cancer surgery with nano-carbon to negatively develop the parathyroid glands significantly reduces the incidence of serum PTH and blood calcium decline, and largely protects the parathyroid glands. Carbon 69-75 parathyroid hormone Homo sapiens 166-169 31293218-7 2021 Three successive runs were conducted in the natural pH (6.8) of 150 mL 100 mg L-1 phenol solution which indicated that the synthesized GrO-3/HKUST-1 composite had satisfactory reusability due to the prevention of carbon deposit and negligible Cu2+ leaching (8 ppm). Carbon 213-219 C-X-C motif chemokine ligand 3 Homo sapiens 135-140 33358038-5 2021 A significantly higher signal for autoantibodies against Rho GDP-dissociation inhibitor 2 (ARHGDIB) was detected in recipients with c-aABMR as compared to recipients with no rejection. Carbon 9-10 Rho GDP dissociation inhibitor beta Homo sapiens 57-89 33358038-5 2021 A significantly higher signal for autoantibodies against Rho GDP-dissociation inhibitor 2 (ARHGDIB) was detected in recipients with c-aABMR as compared to recipients with no rejection. Carbon 9-10 Rho GDP dissociation inhibitor beta Homo sapiens 91-98 33321351-6 2021 Structural analysis showed that activations generated point defects in sp2-carbon structures of biochar, with the material obtained after KOH activation showing a high surface area (569 m2 g-1), an important feature for the use as soil amendment. Carbon 75-81 Sp2 transcription factor Homo sapiens 71-74 32949301-5 2021 Cells were basally stimulated with agonists Pam2CSK4 (Pam; TLR2), polyinosinic/polycytidylic acid (Poly I:C; TLR3), and lipopolysaccharide (LPS; TLR4) for 24 h. Supernatants were evaluated with ELISA for cytokines TNFalpha, IL-6, and IL-1beta. Carbon 0-1 tumor necrosis factor Homo sapiens 214-222 32949301-5 2021 Cells were basally stimulated with agonists Pam2CSK4 (Pam; TLR2), polyinosinic/polycytidylic acid (Poly I:C; TLR3), and lipopolysaccharide (LPS; TLR4) for 24 h. Supernatants were evaluated with ELISA for cytokines TNFalpha, IL-6, and IL-1beta. Carbon 0-1 interleukin 6 Homo sapiens 224-228 32949301-11 2021 Poly I:C induced IL-6 and TNFalpha primarily at the basal side at lower but on both sides at higher concentrations. Carbon 7-8 interleukin 6 Homo sapiens 17-21 32949301-11 2021 Poly I:C induced IL-6 and TNFalpha primarily at the basal side at lower but on both sides at higher concentrations. Carbon 7-8 tumor necrosis factor Homo sapiens 26-34 33476136-8 2021 Two pathways including the direct one-step acid attack at the Pt-C bond (SE2) and stepwise oxidative-addition on the Pt(II) center followed by reductive elimination [SE(ox)] are proposed. Carbon 65-66 fucosyltransferase 2 Homo sapiens 73-76 33476136-9 2021 A detailed density functional theory (DFT) study of these protonations along with experimental UV-vis kinetics suggests that a one-step electrophilic attack (SE2) at the Pt-C bond is the most likely mechanism for complexes 1, and changing the nature of the ancillary ligand can influence the selectivity in the Pt-C bond cleavage. Carbon 173-174 fucosyltransferase 2 Homo sapiens 158-161 33476136-9 2021 A detailed density functional theory (DFT) study of these protonations along with experimental UV-vis kinetics suggests that a one-step electrophilic attack (SE2) at the Pt-C bond is the most likely mechanism for complexes 1, and changing the nature of the ancillary ligand can influence the selectivity in the Pt-C bond cleavage. Carbon 314-315 fucosyltransferase 2 Homo sapiens 158-161 33535440-6 2021 We conclude that the structure of CNM determines the content and/or ratio of sp2 and sp3-hybridized carbon atoms in the material. Carbon 100-106 Sp3 transcription factor Homo sapiens 85-88 33321578-6 2021 Based on voltammetric findings, carbon paste electrode containing graphite powder, paraffin oil, MWCNTs, and DAB was constructed and used for thrombin monitoring after investigation of the DAB oxidation mechanism for the first time. Carbon 32-38 coagulation factor II, thrombin Homo sapiens 142-150 33535440-7 2021 The experimental and literature data demonstrated that sp3-hybridized carbon atoms on the surface are probably the preferable site for catalytic conversion of alcohols. Carbon 70-76 Sp3 transcription factor Homo sapiens 55-58 33513183-4 2021 The results showed that long-term application of NPK plus manure significantly increased soil organic carbon (SOC), total P and available P at all three sites compared with the NPK and CK treatments. Carbon 102-108 tachykinin precursor 1 Homo sapiens 49-52 33526773-3 2021 Normally, the eliminated beta-hydrogen has to be attached to a sp3-carbon. Carbon 67-73 Sp3 transcription factor Homo sapiens 63-66 33526773-4 2021 We envision that the hydrogen elimination from sp2-carbon is possible by using thoroughly designed reaction systems, which may offer a new strategy for the preparation of allenes. Carbon 51-57 Sp2 transcription factor Homo sapiens 47-50 33572605-1 2021 In this study, we successfully synthesized two types of meso/microporous carbon materials through the carbonization and potassium hydroxide (KOH) activation for two different kinds of hyper-crosslinked polymers of TPE-CPOP1 and TPE-CPOP2, which were synthesized by using Friedel-Crafts reaction of tetraphenylethene (TPE) monomer with or without cyanuric chloride in the presence of AlCl3 as a catalyst. Carbon 73-79 pyrin domain containing 1 Homo sapiens 218-223 33572605-1 2021 In this study, we successfully synthesized two types of meso/microporous carbon materials through the carbonization and potassium hydroxide (KOH) activation for two different kinds of hyper-crosslinked polymers of TPE-CPOP1 and TPE-CPOP2, which were synthesized by using Friedel-Crafts reaction of tetraphenylethene (TPE) monomer with or without cyanuric chloride in the presence of AlCl3 as a catalyst. Carbon 73-79 pyrin domain containing 2 Homo sapiens 232-237 33411321-4 2021 The C-10 relative configurations for the pair of C-10 epimers (1 and 2) were established by comparing the magnitude of the computed 13C NMR chemical shifts (Deltadeltacalcd.) Carbon 4-5 homeobox C10 Homo sapiens 49-70 33553104-1 2020 Carbon nanodots (C-dots) with sp2/sp3 framework and diameter of <10 nm contain abundant functional groups or polymers on their surface. Carbon 0-6 Sp2 transcription factor Homo sapiens 30-33 33509226-7 2021 Metabolomics microarray analysis and transcriptome sequencing analysis revealed that GOLPH3L promotes central carbon metabolism in breast cancer by stabilizing the p53 suppressor SERPINE1. Carbon 110-116 tumor protein p53 Homo sapiens 164-167 33439615-0 2021 Coaxial Ni-S@N-Doped Carbon Nanofibers Derived Hierarchical Electrodes for Efficient H2 Production via Urea Electrolysis. Carbon 21-27 solute carrier family 5 member 5 Homo sapiens 8-12 33079413-3 2021 Mechanistical studies indicate that a key step for the radical relay processes is transformations of the aromatic hydrocarbons to the aryl sp2-hybridized carbon-centered radicals via deprotonation of the corresponding aryl radical cation intermediates with bases. Carbon 119-125 Sp2 transcription factor Homo sapiens 139-142 33553104-1 2020 Carbon nanodots (C-dots) with sp2/sp3 framework and diameter of <10 nm contain abundant functional groups or polymers on their surface. Carbon 0-6 Sp3 transcription factor Homo sapiens 34-37 33553904-4 2021 Simultaneously, the removal efficiencies of NO3 --N were 42.8 and 68.4% in these two CWs, while the BbFA content in the substrate and plants with the addition of carbon was lower than that in the Control group. Carbon 162-168 NBL1, DAN family BMP antagonist Homo sapiens 44-47 33461437-2 2022 In this paper, the effects of H2O and CO2 on the simultaneous removal of H2S and SO2 for the by activated carbon (TL-1) were studied. Carbon 106-112 TNF superfamily member 15 Homo sapiens 114-118 33367431-5 2021 Here, we report the preparation, characterisation and in vivo evaluation of tetrazine-functionalised boron-rich carbon dots, which show very fast clearance and low tumour uptake after intravenous administration in a mouse HER2 (human epidermal growth factor receptor 2)-positive tumour model. Carbon 112-118 erb-b2 receptor tyrosine kinase 2 Homo sapiens 234-268 33506074-0 2021 Population of Exciton-Polaritons via Luminescent sp3 Defects in Single-Walled Carbon Nanotubes. Carbon 78-84 Sp3 transcription factor Homo sapiens 49-52 33436009-8 2021 Key rate-limiting enzymes in central carbon metabolic pathways were also found to be malonylated in S. aureus, namely pyruvate kinase (PYK), 6-phosphofructokinase, phosphoglycerate kinase, dihydrolipoyl dehydrogenase, and F1F0-ATP synthase. Carbon 37-43 AT695_RS09030 Staphylococcus aureus 118-133 33467037-3 2021 Although the individual size of WS2 crystallites is found smaller, the joining of grain boundaries due to sp2-bonded carbon nanostructures (~3-6 nm) in GO to reduced graphene-oxide (RGO) transformed film, facilitates the expansion of domain size in continuous fashion resulting in full coverage of the substrate. Carbon 117-123 Sp2 transcription factor Homo sapiens 106-109 33167270-0 2021 A novel electrochemical immunosensor based on acetylene black/epoxy-substituted-polypyrrole polymer composite for the highly sensitive and selective detection of interleukin 6. Carbon 46-61 interleukin 6 Homo sapiens 162-175 33466581-7 2021 In addition, among the carbon sources that drive OXPHOS, glutamine is a very potent inducer of IL6 production. Carbon 23-29 interleukin 6 Mus musculus 95-98 33356271-6 2021 Infrared spectra suggest that hydrogenation products were likely to be formed with sp3 carbon and NH bonding. Carbon 87-93 Sp3 transcription factor Homo sapiens 83-86 33436009-8 2021 Key rate-limiting enzymes in central carbon metabolic pathways were also found to be malonylated in S. aureus, namely pyruvate kinase (PYK), 6-phosphofructokinase, phosphoglycerate kinase, dihydrolipoyl dehydrogenase, and F1F0-ATP synthase. Carbon 37-43 AT695_RS09030 Staphylococcus aureus 135-138 33436009-8 2021 Key rate-limiting enzymes in central carbon metabolic pathways were also found to be malonylated in S. aureus, namely pyruvate kinase (PYK), 6-phosphofructokinase, phosphoglycerate kinase, dihydrolipoyl dehydrogenase, and F1F0-ATP synthase. Carbon 37-43 AT695_RS13775 Staphylococcus aureus 164-187 33413430-4 2021 Interestingly, NK-4 augmented TNF-alpha production by THP-1 macrophages in combination with LPS, Pam3CSK4, or poly(I:C). Carbon 101-102 tumor necrosis factor Homo sapiens 30-39 33440348-0 2021 Multiwalled carbon nanotubes co-delivering sorafenib and epidermal growth factor receptor siRNA enhanced tumor-suppressing effect on liver cancer. Carbon 12-18 epidermal growth factor receptor Homo sapiens 57-89 33440348-1 2021 OBJECTIVE: This study aimed to investigate the effects of multiwalled carbon nanotubes (MWNTs) co-delivering sorafenib (Sor) and epidermal growth factor receptor (EGFR) siRNA (MWNT/Sor/siRNA) on tumor growth in liver cancer (LC). Carbon 70-76 epidermal growth factor receptor Homo sapiens 163-167 33435425-3 2021 DLC films have been deposited by various methods and many deviate from the DLC regions present in the ternary diagrams proposed for sp3 covalent carbon, sp2 covalent carbon, and hydrogen. Carbon 145-151 Sp3 transcription factor Homo sapiens 132-135 33435425-8 2021 The number of carbon atoms in the sp3 covalent carbon without bonding with hydrogen and the logarithm of the hydrogen content were inversely proportional. Carbon 14-20 Sp3 transcription factor Homo sapiens 34-37 33435425-8 2021 The number of carbon atoms in the sp3 covalent carbon without bonding with hydrogen and the logarithm of the hydrogen content were inversely proportional. Carbon 47-53 Sp3 transcription factor Homo sapiens 34-37 33325996-1 2021 Recently, we uncovered the genetic components from six carbon fixation autotrophic pathways in cleaned ultra-small size fractions from marine samples (<0.22 micrometres) gathered worldwide by the Tara Oceans Expedition. Carbon 55-61 TRIO and F-actin binding protein Homo sapiens 196-200 33068589-0 2021 TLR3 inhibitor and tyrosine kinase inhibitor attenuate cigarette smoke/poly I:C-induced airway inflammation and remodeling by the EGFR/TLR3/MAPK signaling pathway. Carbon 78-79 epidermal growth factor receptor Homo sapiens 130-134 33326518-5 2021 Besides FT-IR, the analysis of sp3 carbon (from XPS) turned out to give reasonable insights into capping agent removal. Carbon 35-41 Sp3 transcription factor Homo sapiens 31-34 33191503-2 2021 In this work, the synthesis of a novel bithiophene-bridged donor-acceptor-based 2D sp2 -carbon-linked conjugated polymer (2D CCP) is demonstrated. Carbon 88-94 Sp2 transcription factor Homo sapiens 83-86 33080102-3 2021 Strong agostic interactions with the "C-H"-groups of the cyclohexyl substituents result in an unusual low spin square planar Co II complex, which is unreactive towards external substrates. Carbon 38-39 mitochondrially encoded cytochrome c oxidase II Homo sapiens 125-130 32436837-8 2021 The most important changes occurred in the HIF1alpha and NF-KB signaling pathways targeted genes and in central carbon metabolism pathway genes such as HKs, PFKL, and solute transporters. Carbon 112-118 hypoxia inducible factor 1 subunit alpha Homo sapiens 43-52 33191503-0 2021 Thiophene-Bridged Donor-Acceptor sp2 -Carbon-Linked 2D Conjugated Polymers as Photocathodes for Water Reduction. Carbon 38-44 Sp2 transcription factor Homo sapiens 33-36 33189040-2 2021 To overcome this, current study designed polyaniline functionalized activated carbon (PANi-FAC) composite as capacitive anode with strategic electrocatalytic capability, and was comparatively assessed with SSM-PANi and bare SSM as anodes in three double chambered MFCs respectively. Carbon 78-84 FA complementation group C Homo sapiens 91-94 33285407-2 2021 Through integrating strategies of reducing aromatic character/increasing the fraction of sp3 carbons together with scaffold hopping, we designed and synthesized two new series of thieno[2,3-d]pyrimidine and thiazolo[5,4-d]pyrimidine derivatives for use as PI3K inhibitors. Carbon 93-100 Sp3 transcription factor Homo sapiens 89-92 33518602-5 2021 The 13C-NMR signal at C-10, a quaternary carbon, was correlated with cytotoxicity. Carbon 41-47 chemokine (C-C motif) ligand 6 Mus musculus 22-26 32820441-0 2021 Clay-activated carbon adsorbent obtained by activation of spent bleaching earth and its application for removing Pb(II) ion. Carbon 15-21 submaxillary gland androgen regulated protein 3B Homo sapiens 113-119 32820441-7 2021 Clay/carbon nanocomposites were prepared by carbonizing and activating the spent bleaching earth served as adsorbents for the efficient removal of Pb(II) from wastewater. Carbon 5-11 submaxillary gland androgen regulated protein 3B Homo sapiens 147-153 33309651-3 2021 This was followed by oxidative fragmentation of ring B to the 9,10-secotigliane derivative 6 and oxidation of the endocyclic Delta6 double bond to the C-6/C-10 oxygen bridged 7-oxotigliane 7. Carbon 151-152 homeobox C10 Homo sapiens 155-159 33383149-9 2021 The soluble levels of TNFalpha and IFNgamma were significantly (P <= 0.05) raised in Poly I:C or ConA challenged mice than control mice. Carbon 92-93 tumor necrosis factor Mus musculus 22-30 33531997-0 2021 Carbon ion triggered immunogenic necroptosis of nasopharyngeal carcinoma cells involving necroptotic inhibitor BCL-x. Carbon 0-6 BCL2 like 1 Homo sapiens 111-116 33531997-8 2021 Moreover, carbon ion induced a robust (up to 28 folds) p-MLKL in the PR-NPC cells as well as sensitive cells (up to 6-fold) coupled with a lower level of BCL-x expression and increased GM-CSF implicated in resculputure of immune system. Carbon 10-16 BCL2 like 1 Homo sapiens 154-159 33531997-9 2021 These results suggested that carbon ion could induce necroptosis of NPC cells, especially in PR-NPC cells, and its mechanisms involve BCL-x. Carbon 29-35 BCL2 like 1 Homo sapiens 134-139 32818675-2 2021 In this paper, a novel structure of nitrogen-doped carbon nanotubes-encapsulated cobalt nanoparticles (Co@NCNTs) is synthesized by a simple dual-template strategy using silica colloid and tri-block copolymer (polyethylene oxide-polypropylene oxide-polyethylene oxide, PEO-PPO-PEO, F127) as hard and soft templates, respectively. Carbon 51-57 protoporphyrinogen oxidase Homo sapiens 272-275 33084047-5 2021 An input of ~8 Mg ha-1 carbon with the soil amendments had only minor effects on soil carbon content after four years, likely because of fast microbe-mediated turnover. Carbon 23-29 Rho GTPase activating protein 45 Homo sapiens 18-22 33383149-9 2021 The soluble levels of TNFalpha and IFNgamma were significantly (P <= 0.05) raised in Poly I:C or ConA challenged mice than control mice. Carbon 92-93 interferon gamma Mus musculus 35-43 33517959-3 2021 100 mug/mL carbon black was used to treat HELFs(CB), DN-ERK HELFs(CB-DN-ERK), DN-JNK HELFs(CB-DN-JNK), and HELFs without any black carbon treatment were considered as control group. Carbon 11-17 mitogen-activated protein kinase 1 Homo sapiens 56-59 33338317-8 2021 The conductance of the PBIT-based molecule is higher than that of the tripodal anchor having sp3 carbon atoms in the carrier transport pathway. Carbon 97-103 Sp3 transcription factor Homo sapiens 93-96 33059156-1 2021 To explore the mechanisms that mineralize poorly bioavailable natural organic carbon (OC), we measured the mineralization of OC in two lake waters over long-term experiments (up to 623 days) at different pH and iron (Fe) levels. Carbon 78-84 bone gamma-carboxyglutamate protein Homo sapiens 86-88 32866342-1 2020 The synthetically versatile pinacol boronic ester group (Bpin) is generally thought of as a bulky moiety due to the two adjacent quaternary sp 3 -hydribized carbon atoms in its diol backbone. Carbon 157-163 Sp3 transcription factor Homo sapiens 140-144 33370481-3 2022 This research work introduces a modified interdigitated electrode (IDE) sensing surface constructed with single walled carbon nanotube (SWCN) to detect the cardiac biomarker, C-reactive protein (CRP). Carbon 119-125 C-reactive protein Homo sapiens 175-193 33370481-3 2022 This research work introduces a modified interdigitated electrode (IDE) sensing surface constructed with single walled carbon nanotube (SWCN) to detect the cardiac biomarker, C-reactive protein (CRP). Carbon 119-125 C-reactive protein Homo sapiens 195-198 33458503-2 2021 Using first-principles calculations, we proposed a stable spiral structure of carbon nitride, namely spiral-C3N, which is composed of sp2-hybridized carbon and pyridine nitrogen with a 60 helical symmetry along the z-direction. Carbon 78-84 Sp2 transcription factor Homo sapiens 134-137 33458503-8 2021 Such a new three-dimensional spiral framework of sp2-hyperdized carbon and nitrogen atoms not only enriches the family of carbon nitride materials but also finds application in energy conversion and storage. Carbon 64-70 Sp2 transcription factor Homo sapiens 49-52 33307694-2 2020 Two hydrogenation and one C-C bond coupling products are identified as isomers of [H3C-Pt-H(CO2)]- by a synergy between anion photoelectron spectroscopy and quantum chemical calculations. Carbon 26-27 parathyroid hormone Homo sapiens 87-91 33307694-2 2020 Two hydrogenation and one C-C bond coupling products are identified as isomers of [H3C-Pt-H(CO2)]- by a synergy between anion photoelectron spectroscopy and quantum chemical calculations. Carbon 28-29 parathyroid hormone Homo sapiens 87-91 32902091-0 2020 Forming All-Carbon Quaternary Stereocenters by Organocatalytic Aminomethylation: Concise Access to beta2,2-Amino Acids. Carbon 12-18 ATPase H+ transporting V0 subunit a2 Homo sapiens 99-104 32902091-2 2020 We report here a novel organocatalytic enantioselective aminomethylation of ketenes with stable and readily available N,O-acetals, providing beta 2,2 -amino esters bearing an all-carbon quaternary stereogenic center in high enantiomeric ratios with a catalytic amount of chiral phosphoric acid. Carbon 179-185 immunoglobulin kappa variable 3-25 (pseudogene) Homo sapiens 141-149 33284633-2 2020 The Cu-(2,2,6,6-tetramethylpiperidin-1-yl)oxyl system showed a great ability to activate the C-H bond on the alpha- and beta-carbons of a carbonyl group, and the in situ-generated enone intermediate in this reaction could be further transformed to construct isobenzofuranones with the catalysis of Pd(dba)2 (dba = dibenzylideneacetone). Carbon 125-132 DBA2 Homo sapiens 298-306 33300805-1 2020 Readily available aryldimethylsulfonium triflates react with zinc powder under nickel catalysis via the selective cleavage of the sp2-hybridized carbon-sulfur bond to produce salt-free arylzinc triflates under mild conditions. Carbon 145-151 Sp2 transcription factor Homo sapiens 130-133 33403271-0 2020 Multifunctional Binding Sites on Nitrogen-Doped Carboxylated Porous Carbon for Highly Efficient Adsorption of Pb(II), Hg(II), and Cr(VI) Ions. Carbon 68-74 submaxillary gland androgen regulated protein 3B Homo sapiens 110-116 33252234-1 2020 A dual platform for forging sp2-sp3 and sp3-sp3 carbon bonds via catalytic beta-scission of aliphatic alcohol derivatives with both aryl and alkyl halides is disclosed. Carbon 48-54 Sp2 transcription factor Homo sapiens 28-31 33252234-1 2020 A dual platform for forging sp2-sp3 and sp3-sp3 carbon bonds via catalytic beta-scission of aliphatic alcohol derivatives with both aryl and alkyl halides is disclosed. Carbon 48-54 Sp3 transcription factor Homo sapiens 32-35 33252234-1 2020 A dual platform for forging sp2-sp3 and sp3-sp3 carbon bonds via catalytic beta-scission of aliphatic alcohol derivatives with both aryl and alkyl halides is disclosed. Carbon 48-54 Sp3 transcription factor Homo sapiens 40-43 33252234-1 2020 A dual platform for forging sp2-sp3 and sp3-sp3 carbon bonds via catalytic beta-scission of aliphatic alcohol derivatives with both aryl and alkyl halides is disclosed. Carbon 48-54 Sp3 transcription factor Homo sapiens 40-43 33335403-6 2020 The expression of some apoptotic and autophagy-related genes such as Bax, Bcl2, Beclin1 and ATG7 was significantly induced by carbon-ion beam irradiation alone and was further enhanced when the beam was combined with 5-FU. Carbon 126-132 BCL2 associated X, apoptosis regulator Homo sapiens 69-72 33335403-6 2020 The expression of some apoptotic and autophagy-related genes such as Bax, Bcl2, Beclin1 and ATG7 was significantly induced by carbon-ion beam irradiation alone and was further enhanced when the beam was combined with 5-FU. Carbon 126-132 BCL2 apoptosis regulator Homo sapiens 74-78 33426319-6 2020 Soil organic carbon (SOC) in 0-15 cm soil depth was found to be greater by 16.32% in CA3 than CT plots, whereas SOC was higher by 38.77% and 61.22% in CA6 and CA9. Carbon 13-19 carbonic anhydrase 3 Homo sapiens 85-88 33426319-9 2020 Microbial biomass carbon (MBC) values of the 0-15 cm soil depth were increased over CT by 18.57%, 47.08%, and 71.5% for CA3, CA6, and CA9 respectively. Carbon 18-24 carbonic anhydrase 3 Homo sapiens 120-123 32836125-0 2020 Electro-assisted adsorption of Cs(I) and Co(II) from aqueous solution by capacitive deionization with activated carbon cloth/graphene oxide composite electrode. Carbon 112-118 mitochondrially encoded cytochrome c oxidase II Homo sapiens 41-47 33328306-5 2020 Gene edited PK-15 cell lines were used to show the dsRNA-sensing pathogen recognition receptors (PRRs) TLR3 and RIG-I specifically respond to poly(I:C) and SeV respectively, subsequently triggering apoptosis through pathways that converge on IRF3 and culminate in the cleavage of caspase-3. Carbon 149-150 toll-like receptor 3 Sus scrofa 103-107 33196163-1 2020 This work demonstrates the use of an sp2-bonded carbon microspot boron doped diamond (BDD) electrode for voltammetric measurement of both pH and analyte concentration in a pH-dependent speciation process. Carbon 48-54 Sp2 transcription factor Homo sapiens 37-40 33196163-5 2020 In contrast, it was only the surface integrated quinones (Q) in sp2-bonded carbon regions of the BDD electrode that were responsible for the voltammetric pH signal. Carbon 75-81 Sp2 transcription factor Homo sapiens 64-67 33218476-2 2020 Herein, an immunosensor has been developed for monitoring IL-6, which is fabricated by Au nanoparticles (Au NPs)-thionine (THI)-carboxylated multi walled carbon nanotubes (CMWCNTs) as the substrate with high conductivity. Carbon 154-160 interleukin 6 Homo sapiens 58-62 32987067-3 2020 To meet this demand, 5-fluorouracil-chitosan-carbon quantum dot-aptamer (5-FU-CS-CQD-Apt) nanoparticle was successfully synthesized for specific targeted delivery of 5-FU anti-cancer drug used in breast cancer treatment and this was done by following facile water-in-oil (W/O) emulsification method. Carbon 45-51 LYPLA2 pseudogene 1 Homo sapiens 85-88 33306353-0 2020 sp3-Functionalization of Single-Walled Carbon Nanotubes Creates Localized Spins. Carbon 39-45 Sp3 transcription factor Homo sapiens 0-3 33306353-1 2020 Chemical functionalization-introduced sp3 quantum defects in single-walled carbon nanotubes (SWCNTs) have shown compelling optical properties for their potential applications in quantum information science and bioimaging. Carbon 75-81 Sp3 transcription factor Homo sapiens 38-41 33021232-6 2020 Their surfaces turn from hydrophobic ones rich of sp2-bonded carbon into hydrophilic ones rich of carboxyl derivatives and hydroxyl groups as the crystallization temperature increases. Carbon 61-67 Sp2 transcription factor Homo sapiens 50-53 33324507-2 2020 A commercially available filter uses the adsorption potential of activated carbon for removing heavy metals like Pb(II). Carbon 75-81 submaxillary gland androgen regulated protein 3B Homo sapiens 113-119 33344820-0 2020 Copper-Catalyzed Oxidative Cleavage of the C-C Bonds of beta-Alkoxy Alcohols and beta-1 Compounds. Carbon 0-1 BCL2 related protein A1 Homo sapiens 81-87 33415004-8 2020 When used in combination with miR-29b mimic, carbon ion beam markedly inhibited invasion, migration, and proliferation of OSA cells and promoted apoptosis by inhibiting AKT phosphorylation in a Sp1/PTEN-mediated manner. Carbon 45-51 AKT serine/threonine kinase 1 Homo sapiens 169-172 33415004-9 2020 Taken together, miR-29b mimic improved the radiosensitivity of OSA cells via the PTEN-AKT-Sp1 signaling pathway, presenting a novel strategy for the development of carbon ion beam combination therapy. Carbon 164-170 AKT serine/threonine kinase 1 Homo sapiens 86-89 32897834-0 2020 AtFLL2, a member of the FLO2 gene family, affects the enlargement of leaves at the vegetative stage and facilitates the regulation of carbon metabolism and flow. Carbon 134-140 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 24-28 32818758-0 2020 CRP-binding bacteriophage as a new element of layer-by-layer assembly carbon nanofiber modified electrodes. Carbon 70-76 C-reactive protein Homo sapiens 0-3 32721695-6 2020 More importantly, further redox experiments manifested that the carbon framework (defects, sp2-hybrid carbon, etc.) Carbon 64-70 Sp2 transcription factor Homo sapiens 91-94 32472581-2 2020 We found that a household fluorescent bulb was able to excite diaryl ketone, which then selectively abstracts a H atom from an sp3-C-H bond. Carbon 131-132 Sp3 transcription factor Homo sapiens 127-130 32472581-6 2020 This reaction also can even be performed for the alkynylation of unactivated sp3-C-H bonds, in this case with a preference of the more substituted carbon. Carbon 147-153 Sp3 transcription factor Homo sapiens 77-80 32721695-6 2020 More importantly, further redox experiments manifested that the carbon framework (defects, sp2-hybrid carbon, etc.) Carbon 102-108 Sp2 transcription factor Homo sapiens 91-94 33260358-4 2020 The HL1 ligand results from the condensation of salicylaldehyde and 1-(2-aminoethyl)piperazine, while a new organic ligand, H2L2, was formed by the dimerization of HL1 via a coupling of two piperazine rings of HL1 on a carbon atom coming from DMF solvent. Carbon 219-225 asialoglycoprotein receptor 1 Homo sapiens 164-167 33128823-4 2020 Our transcriptomic and proteomic analysis of patient muscle suggests a stepwise mechanism where first, the integrated stress response associated with increased FGF21 and GDF15 expression enhances the metabolism modulated by serine biosynthesis, one carbon metabolism, TCA lipid oxidation and amino acid availability, while in the second step mTOR activation leads to increased mitochondrial biogenesis. Carbon 249-255 fibroblast growth factor 21 Homo sapiens 160-165 32584476-6 2020 This was further substantiated by pharmacological inhibition of the primary astrocytic GABA transporter subtype 3 (GAT3), by (S)-SNAP-5114 or 1-benzyl-5-chloro-2,3-dihydro-1H-indole-2,3-dione (compound 34), leading to significant reductions in oxidative GABA carbon metabolism. Carbon 259-265 solute carrier family 6 member 13 Homo sapiens 87-113 32584476-6 2020 This was further substantiated by pharmacological inhibition of the primary astrocytic GABA transporter subtype 3 (GAT3), by (S)-SNAP-5114 or 1-benzyl-5-chloro-2,3-dihydro-1H-indole-2,3-dione (compound 34), leading to significant reductions in oxidative GABA carbon metabolism. Carbon 259-265 solute carrier family 6 member 13 Homo sapiens 115-119 32919657-1 2020 A selective and cost-effective biosensor based on catalase immobilized antimonene quantum dots modified glassy carbon electrode (Cat@AMQDs-GCE) is designed for the first time to determine hydrogen peroxide (H2O2). Carbon 111-117 catalase Homo sapiens 50-58 33150721-0 2020 Hierarchical Multicavity Nitrogen-Doped Carbon Nanospheres as Efficient Polyselenide Reservoir for Fast and Long-Life Sodium-Selenium Batteries. Carbon 40-46 Fas activated serine/threonine kinase Homo sapiens 99-103 32827965-10 2020 These results suggested a possible mechanism of carcinogenic: Cd-induced upregulation of CDK6 in esophageal cell lines caused PKM2 overphosphorylation inhibiting PK activity, thereby shunting glucose-derived carbon into the pentose phosphate pathway and promoting the production of NADPH and reduced glutathione (GSH) to neutralize ROS, which finally results in the inhibited apoptosis. Carbon 208-214 cyclin dependent kinase 6 Homo sapiens 89-93 33260358-4 2020 The HL1 ligand results from the condensation of salicylaldehyde and 1-(2-aminoethyl)piperazine, while a new organic ligand, H2L2, was formed by the dimerization of HL1 via a coupling of two piperazine rings of HL1 on a carbon atom coming from DMF solvent. Carbon 219-225 asialoglycoprotein receptor 1 Homo sapiens 164-167 32805118-3 2020 The quaternary carbon is a predominant feature of natural product structures and has been associated with more effectively and selectively binding to target proteins compared to planar compounds with a high sp2 count. Carbon 15-21 Sp2 transcription factor Homo sapiens 207-210 33174871-2 2020 The surface sp2 : sp3 ratio of two types of carbon catalysts, including nanodiamond- and graphite-oriented carbons, both have a volcano relationship with the catalytic performance for acetylene hydrochlorination, and the optimized ratios are both around 32-35%. Carbon 44-50 Sp2 transcription factor Homo sapiens 12-15 33174871-2 2020 The surface sp2 : sp3 ratio of two types of carbon catalysts, including nanodiamond- and graphite-oriented carbons, both have a volcano relationship with the catalytic performance for acetylene hydrochlorination, and the optimized ratios are both around 32-35%. Carbon 44-50 Sp3 transcription factor Homo sapiens 18-21 33174871-2 2020 The surface sp2 : sp3 ratio of two types of carbon catalysts, including nanodiamond- and graphite-oriented carbons, both have a volcano relationship with the catalytic performance for acetylene hydrochlorination, and the optimized ratios are both around 32-35%. Carbon 107-114 Sp2 transcription factor Homo sapiens 12-15 33174871-2 2020 The surface sp2 : sp3 ratio of two types of carbon catalysts, including nanodiamond- and graphite-oriented carbons, both have a volcano relationship with the catalytic performance for acetylene hydrochlorination, and the optimized ratios are both around 32-35%. Carbon 107-114 Sp3 transcription factor Homo sapiens 18-21 33174871-0 2020 Generalized reactivity descriptor of defective carbon catalysts for acetylene hydrochlorination: the ratio of sp2 : sp3 hybridization. Carbon 47-53 Sp2 transcription factor Homo sapiens 110-113 33174871-0 2020 Generalized reactivity descriptor of defective carbon catalysts for acetylene hydrochlorination: the ratio of sp2 : sp3 hybridization. Carbon 47-53 Sp3 transcription factor Homo sapiens 116-119 32805118-5 2020 These characteristics, coupled to an increasing awareness to develop sp3-rich molecules, boosted utility of quaternary carbon stereocenters in bioactive compounds. Carbon 119-125 Sp3 transcription factor Homo sapiens 69-72 33065111-5 2020 The regioselectivity of hydroxylation was broken when the reactive carbon was adjoined with an sp1 or sp2 system. Carbon 67-73 Sp2 transcription factor Mus musculus 102-105 32815658-0 2020 Conformation and Aromaticity Switching in a Curved Non-Alternant sp2 Carbon Scaffold. Carbon 69-75 Sp2 transcription factor Homo sapiens 65-68 33107520-7 2020 The planar geometries of aromatic sp2 carbon networks lead to attractive interactions that are "served up on a molecular pizza peel", and adoption of slip-stacked geometries minimizes steric (rather than electrostatic) repulsion. Carbon 38-44 Sp2 transcription factor Homo sapiens 34-37 33330321-0 2020 Carbon Ion Therapy Inhibits Esophageal Squamous Cell Carcinoma Metastasis by Upregulating STAT3 Through the JAK2/STAT3 Signaling Pathway. Carbon 0-6 signal transducer and activator of transcription 3 Homo sapiens 90-95 33330321-0 2020 Carbon Ion Therapy Inhibits Esophageal Squamous Cell Carcinoma Metastasis by Upregulating STAT3 Through the JAK2/STAT3 Signaling Pathway. Carbon 0-6 signal transducer and activator of transcription 3 Homo sapiens 113-118 33330321-5 2020 Therefore, the aim of the present study was to investigate the relationship between carbon ion inhibition of the proliferation and metastasis of esophageal carcinoma cells and the JAK2/STAT3 signaling pathway. Carbon 84-90 signal transducer and activator of transcription 3 Homo sapiens 185-190 33330321-10 2020 Carbon ion beams also regulated CDH1 and MMP2 downstream of the STAT3 pathway and inhibited ESCC cell metastasis, which activated the STAT3 signaling pathway. Carbon 0-6 cadherin 1 Homo sapiens 32-36 33330321-10 2020 Carbon ion beams also regulated CDH1 and MMP2 downstream of the STAT3 pathway and inhibited ESCC cell metastasis, which activated the STAT3 signaling pathway. Carbon 0-6 signal transducer and activator of transcription 3 Homo sapiens 64-69 33330321-10 2020 Carbon ion beams also regulated CDH1 and MMP2 downstream of the STAT3 pathway and inhibited ESCC cell metastasis, which activated the STAT3 signaling pathway. Carbon 0-6 signal transducer and activator of transcription 3 Homo sapiens 134-139 33518858-5 2020 The developed QSAR models identified number of sp2 hybridized Oxygen atoms within seven bonds from aromatic Carbon atoms, the presence of Carbon and Nitrogen atoms at a topological distance of 3 and other interrelations of atom pairs as important pharmacophoric features. Carbon 108-114 Sp2 transcription factor Homo sapiens 47-50 33147023-2 2020 The formation of a benzylic carbocation species possessing a quaternary sp3-carbon center on the fluorene moiety by an intermolecular oxidative Friedel-Crafts reaction of two different arenes successfully triggered the subsequent ring expansion to afford DAPs. Carbon 76-82 Sp3 transcription factor Homo sapiens 72-75 33210901-4 2020 Targeting the hydrogenolysis of the platform chemical 5-hydroxymethylfurfural (5-HMF), here, we design a polyphenylene (PPhen) framework with purely sp2-hybridized carbons that can isolate 5-HMF via pi-pi stacking, preventing hemiacetal and humin formation. Carbon 164-171 Sp2 transcription factor Homo sapiens 149-152 33201879-8 2020 Increasing the levels of maze straw biochar to 47.25 t ha-1 led to an increase in the total organic carbon of soil, however, the overall amount of macroaggregates and MWD were decreased, which is possibly due to localized changes in microbial habitat. Carbon 100-106 1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic Zea mays 55-59 33237691-2 2000 LDL-C and HDL-C levels were inversely correlated with C-reactive protein (CRP) levels i.e. the lower the LDL-C or HDL-C level the higher the CRP levels. Carbon 3-5 C-reactive protein Homo sapiens 54-72 33237691-2 2000 LDL-C and HDL-C levels were inversely correlated with C-reactive protein (CRP) levels i.e. the lower the LDL-C or HDL-C level the higher the CRP levels. Carbon 3-5 C-reactive protein Homo sapiens 74-77 33237691-2 2000 LDL-C and HDL-C levels were inversely correlated with C-reactive protein (CRP) levels i.e. the lower the LDL-C or HDL-C level the higher the CRP levels. Carbon 3-5 C-reactive protein Homo sapiens 141-144 33182305-5 2020 Among the 20 fluorinated chalcones, compound A3/B3 bearing an indole ring attached to the olefinic carbon have been proved to possess the most antimicrobial activity compared to the standard drugs without showing cytotoxicity on human normal liver cell line (L02). Carbon 99-105 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 Homo sapiens 45-50 33125219-2 2020 In this report, we show how an unusual ring contraction process can be harnessed for TDG-based carbonylative C-C bond activations of cyclopropanes. Carbon 109-110 thymine DNA glycosylase Homo sapiens 85-88 33125219-2 2020 In this report, we show how an unusual ring contraction process can be harnessed for TDG-based carbonylative C-C bond activations of cyclopropanes. Carbon 111-112 thymine DNA glycosylase Homo sapiens 85-88 33125219-3 2020 The method involves the transient installation of an isocyanate-derived TDG, rather than relying on carbonyl condensation events as used in previous TDG-enabled C-C bond activations. Carbon 161-162 thymine DNA glycosylase Homo sapiens 149-152 33125219-3 2020 The method involves the transient installation of an isocyanate-derived TDG, rather than relying on carbonyl condensation events as used in previous TDG-enabled C-C bond activations. Carbon 163-164 thymine DNA glycosylase Homo sapiens 72-75 33125219-3 2020 The method involves the transient installation of an isocyanate-derived TDG, rather than relying on carbonyl condensation events as used in previous TDG-enabled C-C bond activations. Carbon 163-164 thymine DNA glycosylase Homo sapiens 149-152 33121247-0 2020 Ascorbic Acid-PEI Carbon Dots with Osteogenic Effects as miR-2861 Carriers to Effectively Enhance Bone Regeneration. Carbon 18-24 microRNA 2861 Homo sapiens 57-65 33000769-2 2020 The AFP aptamer (AFP-Apt), as the recognition molecule, was immobilized on the surface of a screen-printed carbon electrode, which was modified by gold-platinum metallic nanoparticles and reduced graphene oxide-chitosan-ferrocene nanohybrids (Au-Pt NPs/RGO-CS-Fc), to build the AFP electrochemical aptasensor. Carbon 107-113 alpha fetoprotein Homo sapiens 4-7 33000769-2 2020 The AFP aptamer (AFP-Apt), as the recognition molecule, was immobilized on the surface of a screen-printed carbon electrode, which was modified by gold-platinum metallic nanoparticles and reduced graphene oxide-chitosan-ferrocene nanohybrids (Au-Pt NPs/RGO-CS-Fc), to build the AFP electrochemical aptasensor. Carbon 107-113 alpha fetoprotein Homo sapiens 17-20 33000769-2 2020 The AFP aptamer (AFP-Apt), as the recognition molecule, was immobilized on the surface of a screen-printed carbon electrode, which was modified by gold-platinum metallic nanoparticles and reduced graphene oxide-chitosan-ferrocene nanohybrids (Au-Pt NPs/RGO-CS-Fc), to build the AFP electrochemical aptasensor. Carbon 107-113 alpha fetoprotein Homo sapiens 17-20 33172142-3 2020 The electrochemical results obtained showed that AST alone inhibited the acid-induced corrosion of C1018 carbon steel. Carbon 105-111 solute carrier family 17 member 5 Homo sapiens 49-52 33048560-4 2020 Finally, the density functional theory calculation shows that the inert C-N bond activation reaction is not a concerted process; on the contrary, the coupling reaction first generates indole quaternary ammonium salt, and then C-N bond cleavage occurs via an SN2 process. Carbon 72-73 solute carrier family 38 member 5 Homo sapiens 258-261 32946198-2 2020 Heterogeneous B12-electrocatalysts prepared by a simple electrochemical immobilization technique on graphene-oxide (GO) modified glassy carbon and carbon-paper (CP) electrodes, without any non-degradable polymer-binders, showed a highly stable and well-defined surface-confined redox peak at E o "= -0.138 V vs. RHE with a surface-excess value, Gamma B12 = 4.28 n mol cm -2 . Carbon 136-142 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 14-17 32946198-2 2020 Heterogeneous B12-electrocatalysts prepared by a simple electrochemical immobilization technique on graphene-oxide (GO) modified glassy carbon and carbon-paper (CP) electrodes, without any non-degradable polymer-binders, showed a highly stable and well-defined surface-confined redox peak at E o "= -0.138 V vs. RHE with a surface-excess value, Gamma B12 = 4.28 n mol cm -2 . Carbon 147-153 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 14-17 32474321-3 2020 The sp- and sp2-hybridized carbon, high electrical conductivity, direct band gap, and high intrinsic carrier mobility are key characteristics for GDY to serve as a competitive catalyst support. Carbon 27-33 Sp2 transcription factor Homo sapiens 12-15 32898511-8 2020 RESULTS: LPS and TNFalpha significantly reduce cell viability after 1 day and 7 days, Poly I:C after 7 days and 4 weeks. Carbon 93-94 tumor necrosis factor Homo sapiens 17-25 33095990-1 2020 Pressure-induced polymerization of aromatic compounds leads to novel materials containing sp3 carbon-bonded networks. Carbon 94-100 Sp3 transcription factor Homo sapiens 90-93 33081954-2 2020 The aptasensor was prepared by means of immobilizing thiolated CEA aptasensor on gold nanoparticle-deposited glassy carbon electrode. Carbon 116-122 CEA cell adhesion molecule 3 Homo sapiens 63-66 32590178-0 2020 Corn derivative mesoporous carbon microspheres supported hydrophilic polydopamine for development of new membrane: Water treatment containing bovine serum albumin. Carbon 27-33 albumin Homo sapiens 149-162 33099588-4 2020 Specifically, bovine serum albumin (BSA) was used as a template and reducing agent for preparing a BSA-MnO2 nanozyme; then a BSA-MnO2/IR820@OCNC (BMIOC) nanosystem was successfully synthesized by crosslinking BSA-MnO2 on the surface of IR820-loaded carboxylated carbon nanocages (OCNCs). Carbon 262-268 albumin Homo sapiens 21-34 33089846-1 2020 A benign, efficient, regio- and stereoselective protocol for the syntheses of alpha-1-fluoroalkyl-C-glycosyl compounds bearing CF3, C4F9, and C6F13 substituents on the anomeric carbon has been developed by a new methodology starting from 2-acetoxyglycals for the first time. Carbon 177-183 BCL2 related protein A1 Homo sapiens 78-85 33153238-6 2020 The experimental results show that the RP2 of the three attributes of Total Carbon, Total Nitrogen, and Alkaline Nitrogen on the small dataset are 0.94, 0.95, 0.87, respectively, and the RP2 of the attributes of Organic Carbon, Nitrogen, and Clay on the LUCAS dataset are, respectively, 0.95, 0.91, 0.83, And compared with traditional regression models and new prediction methods commonly used in soil nutrient prediction, the multi-task model proposed in this paper is more accurate. Carbon 76-82 RP2 activator of ARL3 GTPase Homo sapiens 39-42 33153238-6 2020 The experimental results show that the RP2 of the three attributes of Total Carbon, Total Nitrogen, and Alkaline Nitrogen on the small dataset are 0.94, 0.95, 0.87, respectively, and the RP2 of the attributes of Organic Carbon, Nitrogen, and Clay on the LUCAS dataset are, respectively, 0.95, 0.91, 0.83, And compared with traditional regression models and new prediction methods commonly used in soil nutrient prediction, the multi-task model proposed in this paper is more accurate. Carbon 220-226 RP2 activator of ARL3 GTPase Homo sapiens 39-42 33140919-3 2020 alpha,beta -Epoxyketones undergo dissociative electron-transfer reactions with C-O bond cleavage, via both stepwise and concerted mechanisms, depending on their structure. Carbon 79-80 amyloid beta precursor protein Homo sapiens 0-10 32898511-11 2020 TNFalpha secretion is increased by Poly I:C and LPS after 1 day but not at later time points. Carbon 42-43 tumor necrosis factor Homo sapiens 0-8 31787028-5 2020 Besides, the steric hindrance of residue Phe363 in PPARgamma pocket was speculated as the main isoform selectivity mechanism for Picrasidine C, which would be helpful for the design of selective derivatives. Carbon 129-142 peroxisome proliferator activated receptor gamma Homo sapiens 51-60 32515848-8 2020 Based on these data they estimated the magnitude of carbon emissions from the 2015 fire season in Saskatchewan was 36.3 +- 15.0 Tg C. Carbon 52-58 transglutaminase 2 Homo sapiens 128-132 32936395-9 2020 SV40-fibroblasts from three healthy controls produced increasing levels of IFN-lambda and IL-6 after 24 h of stimulation with increasing concentrations of poly(I:C), whereas the production of the cytokines was impaired in TLR3 L742F/WT patient SV40-fibroblasts. Carbon 162-164 interferon alpha 1 Homo sapiens 75-78 32936395-9 2020 SV40-fibroblasts from three healthy controls produced increasing levels of IFN-lambda and IL-6 after 24 h of stimulation with increasing concentrations of poly(I:C), whereas the production of the cytokines was impaired in TLR3 L742F/WT patient SV40-fibroblasts. Carbon 162-164 interleukin 6 Homo sapiens 90-94 32806261-0 2020 Anti-PSMA monoclonal antibody increases the toxicity of paclitaxel carried by carbon nanotubes. Carbon 78-84 folate hydrolase 1 Homo sapiens 5-9 32806275-7 2020 This was accompanied with increased inter-layer spacing, disruption of pure graphitic domains and changes in hybridization of carbon atoms (sp2 to sp3). Carbon 126-132 Sp2 transcription factor Homo sapiens 140-143 32924690-8 2020 Taken together, these data demonstrate that the sp3/sp2 carbon ratio is the key determinant for the toxicity of DNDs, which can be a useful tool for the safer-by-design approach of DNDs and the safety assessment of carbon nanoparticles. Carbon 56-62 Sp3 transcription factor Rattus norvegicus 48-51 32806275-7 2020 This was accompanied with increased inter-layer spacing, disruption of pure graphitic domains and changes in hybridization of carbon atoms (sp2 to sp3). Carbon 126-132 Sp3 transcription factor Homo sapiens 147-150 31758294-2 2020 In this contribution, magnetic carbon nanotube functionalized by polythiophene (CNT-Fe3O4-PTh) acts as an efficient and retrievable host for copper nanoparticles to prepare CNT-Fe3O4-PTh-Cu(I) as a nontoxic and inexpensive catalyst. Carbon 31-37 parathyroid hormone Homo sapiens 90-93 31758294-2 2020 In this contribution, magnetic carbon nanotube functionalized by polythiophene (CNT-Fe3O4-PTh) acts as an efficient and retrievable host for copper nanoparticles to prepare CNT-Fe3O4-PTh-Cu(I) as a nontoxic and inexpensive catalyst. Carbon 31-37 parathyroid hormone Homo sapiens 183-186 31758294-8 2020 Copper(I) nanoparticles supported on magnetic carbon nanotube functionalized by polythiophene (CNT-Fe3O4-PTh-Cu(I)), was prepared and used for ligand- and palladiumfree Suzuki-Miyaura cross-coupling reaction in water/ethanol as a green media in short reaction times with good to excellent yields. Carbon 46-52 parathyroid hormone Homo sapiens 105-108 32924690-0 2020 The sp3/sp2 carbon ratio as a modulator of in vivo and in vitro toxicity of the chemically purified detonation-synthesized nanodiamond via the reactive oxygen species generation. Carbon 12-18 Sp3 transcription factor Rattus norvegicus 4-11 32780351-1 2020 Elongation of very long chain fatty acids-4 (ELOVL4) is essential for synthesis of very long chain polyunsaturated and saturated fatty acids (VLC-PUFA and VLC-SFA, respectively) of chain length greater than 26 carbons. Carbon 210-217 ELOVL fatty acid elongase 4 Rattus norvegicus 45-51 32924690-8 2020 Taken together, these data demonstrate that the sp3/sp2 carbon ratio is the key determinant for the toxicity of DNDs, which can be a useful tool for the safer-by-design approach of DNDs and the safety assessment of carbon nanoparticles. Carbon 56-62 Sp2 transcription factor Rattus norvegicus 52-55 32924690-8 2020 Taken together, these data demonstrate that the sp3/sp2 carbon ratio is the key determinant for the toxicity of DNDs, which can be a useful tool for the safer-by-design approach of DNDs and the safety assessment of carbon nanoparticles. Carbon 215-221 Sp3 transcription factor Rattus norvegicus 48-51 32924690-8 2020 Taken together, these data demonstrate that the sp3/sp2 carbon ratio is the key determinant for the toxicity of DNDs, which can be a useful tool for the safer-by-design approach of DNDs and the safety assessment of carbon nanoparticles. Carbon 215-221 Sp2 transcription factor Rattus norvegicus 52-55 33138431-2 2020 The conformation of a single ULCFA, in which the sn-1 unsaturated chain has 32 carbons, in three types of phospholipid bilayers is studied by molecular dynamics simulations. Carbon 79-86 solute carrier family 38 member 3 Homo sapiens 49-53 33045633-4 2020 In this study, we initially showed that PA-X inhibits NF-kappaB transcription that stimulated by poly(I:C). Carbon 104-106 nuclear factor kappa B subunit 1 Homo sapiens 54-63 32857208-0 2020 Radiosensitization of NSCLC cells to X-rays and carbon ions by the CHK1/CHK2 inhibitor AZD7762, Honokiol and Tunicamycin. Carbon 48-54 checkpoint kinase 1 Homo sapiens 67-71 33107167-1 2020 Nearly 2D diamond, or diamane, is coveted as an ultrathin sp3 -carbon film with unique mechanics and electro-optics. Carbon 63-69 Sp3 transcription factor Homo sapiens 58-61 33118523-0 2020 N-doped carbon dots modified with the epithelial cell adhesion molecule antibody as an imaging agent for HepG2 cells using their ultra-sensitive response to Al3. Carbon 8-14 epithelial cell adhesion molecule Homo sapiens 38-71 33149572-5 2020 Results: Our experimental results indicated that the acidic environment facilitated the release of copper (CuNPs and Cu2+) from the dressings, and prepared C/H/GO/Cu dressings exhibited significant in vitro antimicrobial activities against the two tested bacterial strains (ATCC35984 and ATCC25923). Carbon 107-108 histocompatibility 52 Mus musculus 158-162 33052046-2 2020 This film has a high concentration of sp3 carbon (sp3/sp2 carbon ratio of ~1-1.9) with a hydrogen concentration of 25-44 atom %, which qualifies it as hydrogenated diamond-like carbon. Carbon 42-48 Sp3 transcription factor Homo sapiens 38-41 33052046-2 2020 This film has a high concentration of sp3 carbon (sp3/sp2 carbon ratio of ~1-1.9) with a hydrogen concentration of 25-44 atom %, which qualifies it as hydrogenated diamond-like carbon. Carbon 42-48 Sp3 transcription factor Homo sapiens 50-53 33052046-2 2020 This film has a high concentration of sp3 carbon (sp3/sp2 carbon ratio of ~1-1.9) with a hydrogen concentration of 25-44 atom %, which qualifies it as hydrogenated diamond-like carbon. Carbon 42-48 Sp2 transcription factor Homo sapiens 54-57 33052046-2 2020 This film has a high concentration of sp3 carbon (sp3/sp2 carbon ratio of ~1-1.9) with a hydrogen concentration of 25-44 atom %, which qualifies it as hydrogenated diamond-like carbon. Carbon 58-64 Sp3 transcription factor Homo sapiens 38-41 33052046-2 2020 This film has a high concentration of sp3 carbon (sp3/sp2 carbon ratio of ~1-1.9) with a hydrogen concentration of 25-44 atom %, which qualifies it as hydrogenated diamond-like carbon. Carbon 58-64 Sp3 transcription factor Homo sapiens 38-41 33055208-0 2020 A synthetic mimic of phosphodiesterase type 5 based on corona phase molecular recognition of single-walled carbon nanotubes. Carbon 107-113 phosphodiesterase 5A Homo sapiens 21-45 33195197-8 2020 Both Pex9p- and Pex18p-dependent import routes serve the fast metabolic adaptation to changes of carbon sources in baker"s yeast. Carbon 97-103 Pex18p Saccharomyces cerevisiae S288C 16-22 33055208-4 2020 When complexed to a single-walled carbon nanotube, some of the resulting corona phases demonstrate binding specificity remarkably similar to that of phosphodiesterase type 5 (PDE5), an enzyme that catalyzes the hydrolysis of secondary messenger. Carbon 34-40 phosphodiesterase 5A Homo sapiens 149-173 33055208-4 2020 When complexed to a single-walled carbon nanotube, some of the resulting corona phases demonstrate binding specificity remarkably similar to that of phosphodiesterase type 5 (PDE5), an enzyme that catalyzes the hydrolysis of secondary messenger. Carbon 34-40 phosphodiesterase 5A Homo sapiens 175-179 33114759-6 2020 As expected, the (BiO)2CO3-rGO/Nafion nanocomposite-modified glassy carbon electrode ((BiO)2CO3-rGO-Nafion/GCE) achieved low detection limits of 0.24 mug/L for Pb(II) and 0.16 mug/L for Cd(II), in the linear range of 1.0-60 mug/L, and showed some excellent performance, such as high stability, good selectivity, and sensitivity. Carbon 68-74 submaxillary gland androgen regulated protein 3B Homo sapiens 160-166 33134723-2 2020 While the late-stage introduction of various functionalities at certain positions, namely, C-3, C-4, and C-8, has been widely documented, the straightforward introduction of challenging sp3 carbon-linked acyclic aminoalkyl or aza- and oxacyclic appendages at C-6 and C-7 remains largely underexplored. Carbon 190-196 Sp3 transcription factor Homo sapiens 186-189 32996765-4 2020 All the ThO2 nH2O samples prepared presented amounts of residual carbon and water in the range 0.2-0.3 wt % and n 0.5, respectively. Carbon 65-71 THO complex 2 Homo sapiens 8-12 33068167-1 2020 A novel electrochemical carbon cloth (CC) analysis device (eCAD) is proposed for the determination of Pb2+ in environmental water samples, which was assembled using a single-step functional CC as both the sensing and the substrate material. Carbon 24-30 cadherin 1 Homo sapiens 59-63 33083850-1 2020 A disposable electrochemical immunosensors is presented suitable to detect cancer biomarker p53 using screen-printed carbon electrodes modified with a layer-by-layer (LbL) matrix of carboxylated NiFe2O4 nanoparticles and polyethyleneimine, onto which anti-p53 antibodies were adsorbed. Carbon 117-123 tumor protein p53 Homo sapiens 92-95 33077786-3 2020 Here we have tested the capacity of a carbon material composed of amorphous sp3 carbon backbone, embedded with a percolating network of sp2 carbon domains to sustain neuronal cultures. Carbon 38-44 Sp3 transcription factor Homo sapiens 76-79 32996507-3 2020 For the eight concerted routes, the cooperative bimetallic route in which the middle carbon atom is attacked by the nucleophilic oxygen atom (route VI-m) was calculated to be the most favorable, and among the three catalysts examined H2O-CoIII-OTs was found to be the most active, due to the strong hydrogen bonding between the nucleophilic H2O and the ring oxygen atom in the epoxides as well as the extra pi-pi stacking interaction. Carbon 85-91 mitochondrially encoded cytochrome c oxidase III Homo sapiens 238-243 32777598-5 2020 The use of smaller carbon particles allows reaching the ambitious target value of 1 ng L-1 in a millimetric layer. Carbon 19-25 L1 cell adhesion molecule Homo sapiens 87-90 33066381-0 2020 Graphene Domain Signature of Raman Spectra of sp2 Amorphous Carbons. Carbon 60-67 Sp2 transcription factor Homo sapiens 46-49 33066381-1 2020 The standard D-G-2D pattern of Raman spectra of sp2 amorphous carbons is considered from the viewpoint of graphene domains presenting their basic structure units (BSUs) in terms of molecular spectroscopy. Carbon 62-69 Sp2 transcription factor Homo sapiens 48-51 33057182-0 2020 Author Correction: Synergy between the anthocyanin and RDR6/SGS3/DCL4 siRNA pathways expose hidden features of Arabidopsis carbon metabolism. Carbon 123-129 dicer-like 4 Arabidopsis thaliana 65-69 33240780-3 2020 Herein, a three-phase electrocatalyst through in situ fabrication of Au nanoparticles (NPs) located on hydrophobic carbon fiber paper (Au/o-CFP) is designed. Carbon 115-121 complement factor properdin Homo sapiens 140-143 32701182-4 2020 Elucidation of their (electronic) structures by X ray diffraction and quantum chemistry studies revealed planar geometries and strong hyperconjugation interactions primarily from the C-Al sigma bonds to the empty p orbital of the cationic sp2 carbon center. Carbon 243-249 Sp2 transcription factor Homo sapiens 239-242 32701182-6 2020 Here, strong delocalization of pi electrons spanning the whole carbocycle has been verified, thus providing rare examples of pi aromaticity involving saturated sp3 carbon atoms. Carbon 164-170 Sp3 transcription factor Homo sapiens 160-163 32022959-3 2020 Unexpectedly, it was discovered that the UV-vis spectrum of PRPs reveals a distinct linear relationship between the PRP absorption and the pK a value of a corresponding carbon acid, which is likely due to the energy difference among different RPRs. Carbon 169-180 prion protein Homo sapiens 60-63 33049205-3 2020 show the utility of noninvasive metabolic imaging of labeled carbon transfer from pyruvate to lactate to detect early response and FOXM1-mediated resistance to PI3K inhibition in estrogen-receptor-positive breast cancer. Carbon 61-67 estrogen receptor 1 Homo sapiens 179-196 32803946-1 2020 Myeloperoxidase (MPO), a key enzyme released by neutrophils during inflammation, has been shown to catalyze the biodegradation of carbon nanomaterials. Carbon 130-136 myeloperoxidase Homo sapiens 0-15 32803946-1 2020 Myeloperoxidase (MPO), a key enzyme released by neutrophils during inflammation, has been shown to catalyze the biodegradation of carbon nanomaterials. Carbon 130-136 myeloperoxidase Homo sapiens 17-20 32803946-2 2020 In this work, we perform photoluminescence studies on the MPO-catalyzed oxidation of graphene oxide (GO) and surfactant-coated pristine (6,5) single-walled carbon nanotubes (SWCNTs). Carbon 156-162 myeloperoxidase Homo sapiens 58-61 32803946-9 2020 Our sensors show linear response to MPO oxidative machinery, and hold the promise to be used as self-calibrating carbon nanomaterial-based MPO activity indicators. Carbon 113-119 myeloperoxidase Homo sapiens 36-39 32803946-9 2020 Our sensors show linear response to MPO oxidative machinery, and hold the promise to be used as self-calibrating carbon nanomaterial-based MPO activity indicators. Carbon 113-119 myeloperoxidase Homo sapiens 139-142 32910659-2 2020 Despite the employment of carbenoids as nucleophiles in reactions with carbon-centered electrophiles, sp3-type alkyl halides remain elusive materials for selective one-carbon homologations. Carbon 168-174 Sp3 transcription factor Homo sapiens 102-105 32935977-0 2020 Highly Selective and Active Electrochemical Reduction of CO2 to CO on a Polymeric Co(II) Phthalocyanine@Graphitic Carbon Nitride Nanosheet-Carbon Nanotube Composite. Carbon 114-120 mitochondrially encoded cytochrome c oxidase II Homo sapiens 82-88 32705929-10 2020 AOX and GPT3 activities could also buffer against a down-regulation of photosynthetic capacity by preventing a persistent imbalance between photosynthetic carbon gain and the activity of carbon utilizing sinks. Carbon 155-161 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 0-3 32705929-10 2020 AOX and GPT3 activities could also buffer against a down-regulation of photosynthetic capacity by preventing a persistent imbalance between photosynthetic carbon gain and the activity of carbon utilizing sinks. Carbon 187-193 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 0-3 32350932-6 2020 Mechanistic investigations supported by Density Functional Theory (BP86) reveal that dihydrogen formation takes place in an intramolecular fashion through the participation of a methylene C-H bond of the HBMIM Ph2 ligand and a Co II -H bond through formal heterolytic splitting of the latter. Carbon 188-189 mitochondrially encoded cytochrome c oxidase II Homo sapiens 227-232 32851708-4 2020 For the SWCNT TCFs via BACVD, both carbon conversion efficiency and SWCNT TCF yield can reach three orders of magnitude higher than those with the conventional FCCVD. Carbon 35-41 hepatocyte nuclear factor 4 alpha Homo sapiens 14-17 31838952-1 2020 Plants uniquely have a family of proteins called extra-large G proteins (XLG) that share homology in their C-terminal half with the canonical Galpha subunits; we carefully detail here that Arabidopsis XLG2 lacks critical residues requisite for nucleotide binding and hydrolysis which is consistent with our quantitative analyses. Carbon 107-108 extra-large GTP-binding protein 2 Arabidopsis thaliana 201-205 32862661-7 2020 Homozygous LoF variants in either ABCG5 or ABCG8 led to marked elevations in sitosterol and LDL-C. Of those sitosterolemia families, heterozygous carriers of ABCG5 LoF variants exhibited increased sitosterol and LDL-C levels compared to non-carriers. Carbon 36-37 ATP binding cassette subfamily G member 5 Homo sapiens 158-163 32707312-5 2020 Carbon catabolite repression and various transcriptional factors such as XlnR, Cre, Clr, Ace, and gna1 control expression of genes encoding cellobiohydrolase (CBH), endoglucanase (EGL) and beta-glucosidase (BGL). Carbon 0-6 angiotensin I converting enzyme Homo sapiens 89-92 32521046-5 2020 Furthermore, we show that both PIFs and ARF18 directly repress Qua-Quine Starch (QQS), which controls the allocation of carbon and nitrogen. Carbon 120-126 auxin response factor 18 Arabidopsis thaliana 40-45 32940310-2 2020 Here, we predict a new allotrope of graphene, named Me-graphene, composed of both sp2- and sp3-hybridized carbon by topological assembly of C-(C3H2)4 molecules. Carbon 106-112 Sp3 transcription factor Homo sapiens 91-94 32940310-3 2020 With a transitional ratio of sp2- and sp3-hybridized carbon atoms (12 : 1) between those of graphene (1 : 0) and penta-graphene (2 : 1), Me-graphene has transition properties between those of graphene and penta-graphene, such as energy, band gap, and Poisson"s ratio. Carbon 53-59 Sp3 transcription factor Homo sapiens 38-41 32940310-8 2020 The transitional properties related to the ratio of sp2- and sp3-hybridized carbon atoms are inspiring for searching for new graphene allotropes with combinational properties. Carbon 76-82 Sp3 transcription factor Homo sapiens 61-64 32780060-1 2020 Five new N-phenyl-carbazole benzopyrans bearing different substitutions on one of the phenyl rings at the sp3 carbon have been synthesized. Carbon 110-116 Sp3 transcription factor Homo sapiens 106-109 32799169-8 2020 Therefore, NSP1 of PRRSV-2 inhibited the mRNA transcription of ccn1 and ccn2 by blocking the ERK-AP-1 axis in Poly I:C stimulated pig macrophages. Carbon 117-118 mitogen-activated protein kinase 1 Homo sapiens 93-96 32865862-2 2020 Herein, a DSN-coupled graphene nanoarray/gold nanoparticles (GNAs/AuNPs) carbon paper (CP) electrode for the dynamic, sensitive, and real-time analysis of miRNAs is reported. Carbon 73-79 GNAS complex locus Homo sapiens 61-65 32893483-4 2020 The hollow mesoporous carbon spheres supported Ni-N4 catalyst (Ni/HMCS-3-800) exhibits superior catalytic activity toward the electrocatalytic CO2 reduction reaction (CO2 RR). Carbon 22-28 MKKS centrosomal shuttling protein Homo sapiens 66-70 32997231-1 2020 The defects into the hexagonal network of a sp2-hybridized carbon atom have been demonstrated to have a significant influence on intrinsic properties of graphene systems. Carbon 59-65 Sp2 transcription factor Homo sapiens 44-47 32726742-0 2020 Activated carbon and organic matter characteristics impact the adsorption of DBP precursors when chlorine is added prior to GAC contactors. Carbon 10-16 D-box binding PAR bZIP transcription factor Homo sapiens 77-80 33101030-9 2020 Furthermore, docking of AM9338 into the CYP3A4 metabolic enzyme corroborates with our experimental findings, and the modelling results also provide a possible mechanism for the unusual susceptibility of adamantyl secondary carbons to metabolic oxidations. Carbon 223-230 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 40-46 32503020-5 2020 The data bit of carbon-based resistive probe memory, considered as the sp2 filament inside sp3 background, is formed completely underneath the tip edge owing to the localized electric field induced here. Carbon 16-22 Sp2 transcription factor Homo sapiens 71-74 33003408-4 2020 gcr2 deletion reduced cellular growth in glucose but significantly increased growth when xylose was the sole carbon source. Carbon 109-115 Gcr2p Saccharomyces cerevisiae S288C 0-4 32907502-1 2022 Combination of "green" coagulation and powdered activated carbon adsorption was tested for removal of benzophenone (BP), benzophenone-3 (BP-3) and caffeine (CF) from treated municipal wastewater at realistic concentration levels (1 to 2 microg/L). Carbon 58-64 BP3 Homo sapiens 121-135 32902530-4 2020 The photoreduced graphene oxide displayed a fragmented sp2 network due to the formation of a high density of defects (carbon vacancies) and the selective removal of epoxides and hydroxyl groups. Carbon 118-124 Sp2 transcription factor Homo sapiens 55-58 32961733-4 2020 From the four discriminant functions, it can be extracted that the presence of sp3 carbons, ramifications, and secondary amine groups in a molecule enhance antibacterial activity, whereas the presence of 5-member rings, sp2 carbons, and sp2 oxygens hinder it. Carbon 83-90 Sp3 transcription factor Homo sapiens 79-82 32961733-4 2020 From the four discriminant functions, it can be extracted that the presence of sp3 carbons, ramifications, and secondary amine groups in a molecule enhance antibacterial activity, whereas the presence of 5-member rings, sp2 carbons, and sp2 oxygens hinder it. Carbon 83-90 Sp2 transcription factor Homo sapiens 237-240 32503020-5 2020 The data bit of carbon-based resistive probe memory, considered as the sp2 filament inside sp3 background, is formed completely underneath the tip edge owing to the localized electric field induced here. Carbon 16-22 Sp3 transcription factor Homo sapiens 91-94 33195001-2 2020 The catalytic system utilizes the alpha-carbonyl sulfoxonium ylide as both the directing group for ortho-sp2 C-H activation and the acylmethylating reagent for C-C coupling. Carbon 109-110 Sp2 transcription factor Homo sapiens 105-108 32791829-4 2020 These are derived from their highly pi-conjugated structures having semiconducting crystalline sp2 carbon networks with defined nanoarchitectures that afford a strong quantum confinement and weak dielectric screening. Carbon 99-105 Sp2 transcription factor Homo sapiens 95-98 32791829-7 2020 A breakthrough regarding the efficient use of the mobile exciton for PL has recently been achieved by local chemical functionalization of the SWCNTs, in which the chemical reactions introduce local defects of oxygen and sp3 carbon atoms in the tube structures. Carbon 224-230 Sp3 transcription factor Homo sapiens 220-223 33042141-7 2020 High mortality after low dose LPS challenge in Gate-16 -/- Gabarap -/- mice primed with poly(I:C) or polymicrobial sepsis was ameliorated by compound GBP2 deficiency. Carbon 95-97 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2 Mus musculus 47-54 32644794-0 2020 Toxicity alleviation of carbon dots from roast beef after forming protein coronas with human serum albumin. Carbon 24-30 albumin Homo sapiens 93-106 32516461-5 2020 They also suggest that the carbon van der Waals (vdW) radii originally derived for sp3carbons should not be used for the smaller sp2 atoms. Carbon 27-33 Sp3 transcription factor Homo sapiens 83-86 32558106-2 2020 due to the unique structure combines sp- and sp2 hybrid carbon network. Carbon 56-62 Sp2 transcription factor Homo sapiens 45-48 32914690-7 2022 The increase in carbon layers is associated with an increasing number of edge sp3 -type carbon, providing greater curvature, further increase the surface reactivity responsible for high binding efficiency. Carbon 16-22 Sp3 transcription factor Homo sapiens 78-81 32914690-7 2022 The increase in carbon layers is associated with an increasing number of edge sp3 -type carbon, providing greater curvature, further increase the surface reactivity responsible for high binding efficiency. Carbon 88-94 Sp3 transcription factor Homo sapiens 78-81 32901375-5 2020 SA1 and SA2 concentrations correlated well with the traffic-related pollutants NOx (r = 0.64 and 0.78) and equivalent black carbon (r = 0.53 and 0.51). Carbon 124-130 stromal antigen 1 Homo sapiens 0-3 33124270-2 2020 A thermal optical carbon analyzer (IMPROVE-TOR) was employed to measure the mass fraction of organic carbon (OC) and elemental carbon (EC) in PM2.5. Carbon 18-24 RAR related orphan receptor C Homo sapiens 43-46 32917021-1 2020 The steel-wire-carbon-fiber-reinforced plate (SCFR plate) is a relatively new strengthening technology for concrete structures. Carbon 15-21 KIT proto-oncogene, receptor tyrosine kinase Homo sapiens 46-50 32334288-2 2020 Herein, nanoarchitecture of Mxene/carbon nanohorns/beta-cyclodextrin-Metal-organic frameworks (MXene/CNHs/beta-CD-MOFs) was exploited as electrochemical sensing platform for carbendazim (CBZ) pesticide determination. Carbon 34-40 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 106-113 32568423-3 2020 Atomic replacements of the Fe II by other metal(II) ions (e.g., Zn II /Co II ) via synthesizing isostructural trinuclear-complex precursors (Fe 2 Zn/Fe 2 Co), namely the "heteroatom modulator approach", realizes the inhibition of iron atoms aggregating toward nanoclusters with formation of a stable iron-dimer cluster in an optimal metal-nitrogen moiety within the carbon layer, clearly identified by direct transmission electron microscope imaging with X-ray absorption fine structure analyses. Carbon 366-372 mitochondrially encoded cytochrome c oxidase II Homo sapiens 71-76 32743870-5 2020 Here, it is confirmed that ideal graphene is quasi-impermeable to protons, yet the most common defect in sp2 carbons, the topological Stone-Wales defect, has a calculated penetration barrier below 1 eV and H+ -over-D+ selectivity of 7 at room temperature and, thus, explains all experimental results on graphene membranes that are available to date. Carbon 109-116 Sp2 transcription factor Homo sapiens 105-108 32923700-7 2020 We showed stimulation of polyinosinic:polycytidylic acid (poly I:C), which led BEAS-2B to produce interferon (IFN)-beta. Carbon 65-66 IFN1@ Homo sapiens 98-119 32700107-7 2020 The mutation sites of GNAS mutation in PMP are relatively stable, usually at Chr20: 57,484,420 (base pair: C-G) and Chr20: 57,484,421 (base pair: G-C). Carbon 77-78 GNAS complex locus Homo sapiens 22-26 32274831-1 2020 Despite the significant progress of the enantioselective reaction using chiral catalysts, the enantioselective nucleophilic substitution reaction at the chiral sp 3 -hybridized carbon atom of a racemic electrophile has not been largely explored. Carbon 177-183 Sp3 transcription factor Homo sapiens 160-164 32841210-4 2020 It is found that EH1 and EH3 are two different charge states of the same defect, labeled EH-center, that anneals out with an activation energy of ~1.1 eV and whose nature is related to a carbon interstitial. Carbon 187-193 epoxide hydrolase 3 Homo sapiens 25-28 32661062-9 2020 AtGA2ox9 oxidizes carbon-20 to form tricarboxylic acid C20-GAs, whereas AtGA2ox10 produces C19-GA9. Carbon 18-24 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 0-8 32498866-0 2020 Zwitterionic polymer chain-assisted lysozyme imprinted core-shell carbon microspheres with enhanced recognition and selectivity. Carbon 66-72 lysozyme Homo sapiens 36-44 32498866-2 2020 In this work, upon the participating of a zwitterionic polymer chain (Poly (1-vinyl-3-sulfopropylimidazolium), PVSP), a lysozyme imprinted core-shell carbon microsphere (CFC-PVSP@MIPs) was prepared by combining template immobilization method and surface imprinting technology. Carbon 150-156 lysozyme Homo sapiens 120-128 32619684-5 2020 Nonracemic compositions and pronounced stable carbon isotope fractionation (Deltadelta13C > 1%) of PCB congeners were observed, confirming that in situ degradation occurred in the sediment cores. Carbon 46-52 pyruvate carboxylase Homo sapiens 99-102 32738418-4 2020 MATERIALS AND METHODS: The role of CYLD in PD-L1 expression was assessed by knockdown of CYLD in TET cells upon stimulation with interferon gamma (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha) or polyinosinic-polycytidylic acid (poly I:C). Carbon 35-36 tumor necrosis factor Homo sapiens 159-186 32538272-0 2020 Multi-walled carbon nanotubes induce IL-1beta secretion by activating hemichannels-mediated ATP release in THP-1 macrophages. Carbon 13-19 GLI family zinc finger 2 Homo sapiens 107-112 32875086-0 2020 sp2/sp3 Hybridized Carbon as an Anode with Extra Li-Ion Storage Capacity: Construction and Origin. Carbon 19-25 Sp2 transcription factor Homo sapiens 0-3 32875086-0 2020 sp2/sp3 Hybridized Carbon as an Anode with Extra Li-Ion Storage Capacity: Construction and Origin. Carbon 19-25 Sp3 transcription factor Homo sapiens 4-7 32573604-4 2020 Furthermore, under acidic conditions (0.5 mol L-1 of HCl), hydrothermal synthesis (250 C for 1 h) was used for synthesizing new carbon dots (sPOD-CDs) of methylthymol blue (0.08 g L-1)/FeCl3 (0.8 g L-1), which is a simulative enzyme for POD, and it was first used for catalyzing the guaiacol/H2O2 reaction within the FIA system to replace natural HRP in the extinction reaction. Carbon 129-135 L1 cell adhesion molecule Homo sapiens 46-49 32829711-12 2020 CONCLUSIONS: Our study provides evidence that altered CX3CL1-CX3CR1 and/or CD200-CD200R pathways, emerging after prenatal immune challenge with LPS and Poly I:C, might be involved in the aetiology of schizophrenia. Carbon 0-1 C-X3-C motif chemokine ligand 1 Rattus norvegicus 54-60 32736713-1 2020 The homogeneous dumbbell-like Au nanoparticles (DL-AuNPs) with large exposed active surfaces were obtained with a porous N-doped carbon aerogel (NCA). Carbon 129-135 CEA cell adhesion molecule 4 Homo sapiens 145-148 32736713-3 2020 The unique structures of NCA@DL-AuNPs yielded better electrocatalytic activity for the detection of H2O2 both in PBS and released from Hale cells than that of previously reported Au catalysts loaded on carbon materials, which demonstrates that such novel NCA@DL-AuNPs nanocomposite is promising for design of efficient nonenzymatic H2O2 biosensors. Carbon 202-208 CEA cell adhesion molecule 4 Homo sapiens 25-37 32736713-3 2020 The unique structures of NCA@DL-AuNPs yielded better electrocatalytic activity for the detection of H2O2 both in PBS and released from Hale cells than that of previously reported Au catalysts loaded on carbon materials, which demonstrates that such novel NCA@DL-AuNPs nanocomposite is promising for design of efficient nonenzymatic H2O2 biosensors. Carbon 202-208 CEA cell adhesion molecule 4 Homo sapiens 255-267 32573604-4 2020 Furthermore, under acidic conditions (0.5 mol L-1 of HCl), hydrothermal synthesis (250 C for 1 h) was used for synthesizing new carbon dots (sPOD-CDs) of methylthymol blue (0.08 g L-1)/FeCl3 (0.8 g L-1), which is a simulative enzyme for POD, and it was first used for catalyzing the guaiacol/H2O2 reaction within the FIA system to replace natural HRP in the extinction reaction. Carbon 129-135 L1 cell adhesion molecule Homo sapiens 181-184 32573604-4 2020 Furthermore, under acidic conditions (0.5 mol L-1 of HCl), hydrothermal synthesis (250 C for 1 h) was used for synthesizing new carbon dots (sPOD-CDs) of methylthymol blue (0.08 g L-1)/FeCl3 (0.8 g L-1), which is a simulative enzyme for POD, and it was first used for catalyzing the guaiacol/H2O2 reaction within the FIA system to replace natural HRP in the extinction reaction. Carbon 129-135 L1 cell adhesion molecule Homo sapiens 181-184 32806906-4 2020 Here, we show that a large music festival held adjacent to the Traisen River in Austria increased the river"s dissolved organic carbon (DOC) concentration from 1.6 to 2.1 mg L-1 and stream ecosystem respiration from -3.2 to -4.5 mg L-1. Carbon 128-134 L1 cell adhesion molecule Homo sapiens 174-177 32905343-2 2020 In this paper, the adsorption property of two kinds of key SF6 carbon-containing decomposition components (CS2 and COF2) on nitrogen-doped anatase TiO2(101) (N-TiO2) surfaces was simulated and analyzed based on density functional theory. Carbon 63-69 chorionic somatomammotropin hormone 2 Homo sapiens 107-110 32824595-3 2020 Of the various TLR ligands examined, the TLR3-specific ligand polyinosinic:polycytidylic acid (poly I:C), significantly induced TNF production and the upregulation of other TLR transcripts, in particular, TLR2. Carbon 102-103 tumor necrosis factor Mus musculus 128-131 32974200-14 2020 Carbon-ion radiation enhanced CRT expression compared to photon and proton radiation. Carbon 0-6 calreticulin Homo sapiens 30-33 32974200-21 2020 Carbon-ion radiation could induce the highest CRT and PDL1 expression under normoxia. Carbon 0-6 calreticulin Homo sapiens 46-49 32605369-4 2020 Furthermore, the 4-C atom linker is the optimal and produces the most potent inhibitor (Ki, app = 130 +- 40 pM) for NTMT1 to date, displaying over 3,000-fold selectivity over other methyltransferases and even to its homolog NTMT2. Carbon 19-20 N-terminal Xaa-Pro-Lys N-methyltransferase 1 Homo sapiens 116-121 32662651-9 2020 The intra-atomic energy changes that occur in these systems are related to the hybridization of the heavy atoms in an analogous manner to the hybridization of C in CH4 from (2s)2(2p)2 to sp3 hybrid orbitals. Carbon 159-160 Sp3 transcription factor Homo sapiens 187-190 32806906-4 2020 Here, we show that a large music festival held adjacent to the Traisen River in Austria increased the river"s dissolved organic carbon (DOC) concentration from 1.6 to 2.1 mg L-1 and stream ecosystem respiration from -3.2 to -4.5 mg L-1. Carbon 128-134 L1 cell adhesion molecule Homo sapiens 232-235 32375068-9 2020 The organic carbon fraction was a more important controlling factor for PFAS sediment levels than cations content. Carbon 12-18 phosphoribosylformylglycinamidine synthase Homo sapiens 72-76 33986909-0 2021 Making the "C-ACE" for a Culturally-Informed Adverse Childhood Experiences Framework to Understand the Pervasive Mental Health Impact of Racism on Black Youth. Carbon 12-13 angiotensin I converting enzyme Homo sapiens 14-17 33455171-0 2020 Functionalized Carbon Nanotube-Embedded Poly(vinyl alcohol) Microspheres for Efficient Removal of Tumor Necrosis Factor-alpha. Carbon 15-21 tumor necrosis factor Rattus norvegicus 98-125 33455171-3 2020 In this study, a series of functionalized carbon nanotube-embedded poly(vinyl alcohol) (PVA) nanocomposite adsorbents were prepared for TNF-alpha removal for the first time. Carbon 42-48 tumor necrosis factor Rattus norvegicus 136-145 33455171-5 2020 Adsorption tests showed that the carboxylated carbon nanotube-embedded composite microspheres (PVA/MWCNTs-COOH) possessed much better adsorption capacity for TNF-alpha in both simulated serum solution and rat plasma compared to the aminated (PVA/MWCNTs-NH2) and raw carbon nanotube-embedded microspheres (PVA/MWCNTs-raw). Carbon 46-52 tumor necrosis factor Rattus norvegicus 158-167 33455181-5 2020 The modified carbon dots also promote dual-action on HIV-1 treatment by both intracellularly and extracellularly viral blocking by combining with the Duviral drug, along with compressing p24 antigen signals that are better than APBA-CDs and Duviral itself. Carbon 13-19 transmembrane p24 trafficking protein 2 Homo sapiens 187-190 32678601-0 2020 C-N and C-O Bonds Formation in Copper-Catalyzed/Mediated sp3 C-H Activation: Mechanistic Studies from Experimental and Computational Aspects. Carbon 0-1 Sp3 transcription factor Homo sapiens 57-60 32305837-3 2020 A significant enhancement in fluorescence emission band centered at 450 nm was observed in the ethanolic solution of HL1 with addition of Zn2+, while remarkably lower fluorescence emission enhancement was obtained in the case of HL2 in which one methyl group was introduced to the azomethine carbon. Carbon 292-298 asialoglycoprotein receptor 1 Homo sapiens 117-120 32662619-4 2020 Experimental results and theoretical calculation disclose that the implanted Ni nanoparticles and highly graphitic sp2 carbon nanocages together with doped N-heteroatoms not only provide synergetic trapping-catalytic-conversion effect for regulating soluble polysulfides with promoted redox kinetics in the cathode at both room and elevated (55 C) temperature, but also yield Ni-enhanced lithiophilic N-heteroatom active sites in the host framework to control Li deposition and suppress Li-dendrite growth in anodes. Carbon 119-125 Sp2 transcription factor Homo sapiens 115-118 32753658-0 2020 Single-site pyrrolic-nitrogen-doped sp2-hybridized carbon materials and their pseudocapacitance. Carbon 51-57 Sp2 transcription factor Homo sapiens 36-39 32753658-1 2020 Integrating nitrogen species into sp2-hybridized carbon materials has proved an efficient means to improve their electrochemical performance. Carbon 49-55 Sp2 transcription factor Homo sapiens 34-37 31655859-2 2020 In Saccharomyces cerevisiae, inactivation of POR1, encoding VDAC1, produces defective growth in the presence of non-fermentable carbon source. Carbon 128-134 porin POR1 Saccharomyces cerevisiae S288C 45-49 32905515-0 2020 Combination of carbon-ion beam and dual tyrosine kinase inhibitor, lapatinib, effectively destroys HER2 positive breast cancer stem-like cells. Carbon 15-21 erb-b2 receptor tyrosine kinase 2 Homo sapiens 99-103 32905515-8 2020 Altogether, combination of carbon-ion beam irradiation and lapatinib has a high potential to kill HER2-positive breast CSCs, causing severe irreparable DNA damage, enhanced autophagy, and apoptosis. Carbon 27-33 erb-b2 receptor tyrosine kinase 2 Homo sapiens 98-102 32537946-3 2020 Herein, a new design approach is reported to control singlet-triplet energy splitting ( EST ) in graphene quantum dots (GQD)/graphene oxide quantum dots (GOQDs) by varying the ratio of oxygenated carbon to sp2 carbon (gammaOC ). Carbon 210-216 Sp2 transcription factor Homo sapiens 206-209 32305864-4 2020 Herein, we developed an in vivo electrochemical immunosensing device based on glassy carbon rod to simultaneously detect three proinflammatory cytokines (IL-1beta, IL-6 and TNF-alpha). Carbon 85-91 interleukin 6 Homo sapiens 164-168 32305864-4 2020 Herein, we developed an in vivo electrochemical immunosensing device based on glassy carbon rod to simultaneously detect three proinflammatory cytokines (IL-1beta, IL-6 and TNF-alpha). Carbon 85-91 tumor necrosis factor Homo sapiens 173-182 32761338-12 2020 CONCLUSION: QHC combination yielded synergy in promoting Schwann cell differentiation and myelination and the protective effect may involve in the inhibition of ERK signaling pathway, providing scientific evidence for better understanding of combination of Q, H and C in clinical applications. Carbon 0-1 mitogen-activated protein kinase 1 Homo sapiens 161-164 32686320-4 2020 This involves loading metal precursors into HMCS templates using a repeated "drop and drying" process followed by selenization at various temperatures, facilitating not only the preparation of bimetallic selenide/carbon composites but also controlling their structures. Carbon 213-219 MKKS centrosomal shuttling protein Homo sapiens 44-48 31543002-1 2020 Abbreviations A Active ABNR Adopted basis Newton-Raphson CARDs Caspase activation and recruitment domains CTD C-terminal domain dsRNA Double-stranded RNA HEL1 Helicase1 HEL2 Helicase2 HEL2i Helicase2 insertion MD Molecular dynamics NA Inactive P Pincer PDB protein data bank PME Particle mesh Ewald RIG-I Retinoic acid-inducible gene-I RMSD Root mean square deviation RMSF Root mean square fluctuation SD Steepest descent TI Thermodynamic Integration Communicated by Ramaswamy H. Sarma. Carbon 57-58 cystatin B Homo sapiens 275-278 32238907-10 2020 Our results demonstrate that SNP rs2236225 in the CpG site of MTHFD1, which regulates allele-specific gene expression in PBMCs is methylation dependent and may perturb one-carbon metabolism pathway in T2D subjects. Carbon 172-178 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 62-68 32480027-8 2020 Increasing HAs concentration from 0 to 15 mg L-1 at pH 5.5 inhibited aggregations but enhanced dissolution of the uncoated and carbon-coated Cu-NPs. Carbon 127-133 L1 cell adhesion molecule Homo sapiens 45-48 32736477-8 2020 XPS also confirmed the presence of carbon in the form of sp3(C-C), sp2(C=C), C-O, and C=O bonds in the Si-DLC coatings; it showed that postprocessing treatments significantly increased the percentage of oxygen in the Si-DLC coatings. Carbon 35-41 Sp2 transcription factor Mus musculus 67-70 32551529-6 2020 Within a narrow window of c-NP per area vertically aligned carbon nanotubes (VA-CNT) of great lengths are obtained. Carbon 59-65 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 26-30 32613826-4 2020 The sp2 carbon-rich A-PD enhances the electrochemical performance and the overall photon-to-electrical conversion and storage efficiency for self-powered devices by the formation of the bridge of electrons between the ionized polymer and metal ion. Carbon 8-14 Sp2 transcription factor Homo sapiens 4-7 32775930-4 2020 With a further increase of carbon number, (P 1-2, T 1-2) moves to the lower-pressure and -temperature region and (P 2-3, T 2-3) gradually moves to the lower-pressure and higher-temperature region. Carbon 27-33 DNA polymerase epsilon 4, accessory subunit Homo sapiens 43-55 32712310-3 2020 Here, we collate research related to the fraction of sp3 carbon atoms (Fsp3), including related high-throughput screening (HTS) cases, structural modifications based on Fsp3, and strategies to improve it. Carbon 57-63 Sp3 transcription factor Homo sapiens 53-56 32378311-2 2020 The dimeric alumoxane [K{Al(NON Dipp )(O)}] 2 reacts with carbon monoxide to afford the oxygen analogue of 3 , [K{Al(NON Dipp )(O 2 C)}] 2 [ 4 ] 2 containing the hitherto unknown ethenetetraolate ligand, [C 2 O 4 ] 4- . Carbon 132-133 nudix hydrolase 3 Homo sapiens 121-125 32206788-5 2020 In addition, during N assimilation, carbon skeletons are required to synthesize amino acids, thus the combination of NO3- or NH4+ transport and assimilation results in different net charge and numbers of protons in plant cells. Carbon 36-42 NBL1, DAN family BMP antagonist Homo sapiens 117-120 32633314-2 2020 The C-H functionalization of the benzylic sp3 carbon is achieved by di-t-butyl peroxide under air, and the subsequent amination-aerobic oxidation process completes the annulation process. Carbon 46-52 Sp3 transcription factor Homo sapiens 42-45 32584038-5 2020 For UWDM of type 1, beta-3 and 5, where the MIM resides in a relatively spacious void, u is in the 1-3 kT, R in the (1.0-2.5)x106 s-1, and R in the (0.4-2.5)x104 s-1 range; the deuterium is bonded to a carbon atom with tetrahedral coordination character. Carbon 204-210 immunoglobulin kappa variable 2D-28 Homo sapiens 4-32 32584038-6 2020 For UWDM of type 2 and alpha-3, where the MIM resides in a much tighter space, a substantial change in the symmetry of u, and the coordination character of the 2H-bonded carbon, are detected at higher temperatures. Carbon 170-176 immunoglobulin kappa variable 2D-28 Homo sapiens 12-30 32597179-5 2020 As the sp3 hybridized carbon (C1) in these dienes interrupts the conjugation path between the donor to the acceptor, the system conceptually resembles a Frustrated Lewis Pair (FLP). Carbon 22-28 Sp3 transcription factor Homo sapiens 7-10 32410390-3 2020 We demonstrate that plumbagin and structurally related 1,4-naphthoquinones with at least one unsubstituted quinoid carbon (C2 or C3) bind to albumin, an ubiquitously present nucleophile, with minimum recovery of free drug. Carbon 115-121 albumin Homo sapiens 141-148 32638763-4 2020 Our results reveal that the removal of a carbon atom in the BL framework that was originally bonded to a Si atom in the substrate is preferred over that of a sp2-bonded atom. Carbon 41-47 Sp2 transcription factor Homo sapiens 158-161 32707696-3 2020 Carbon nanohorns are conical nanostructures made of sp2 carbon sheets that form aggregated superstructures during their synthesis. Carbon 0-6 Sp2 transcription factor Homo sapiens 52-55 32707696-3 2020 Carbon nanohorns are conical nanostructures made of sp2 carbon sheets that form aggregated superstructures during their synthesis. Carbon 56-62 Sp2 transcription factor Homo sapiens 52-55 32039447-7 2020 SDS-PAGE of immunoisolates obtained from TNF-alpha-treated N2a cells by using anti-C-terminal of APP revealed the presence of SDS-stable complexes between HS and the C-terminal fragment of beta-cleaved APP (betaCTF) migrating in the range 10-18 kDa. Carbon 83-84 tumor necrosis factor Mus musculus 41-50 32493730-0 2020 A requirement for an active proton delivery network supports a compound I-mediated C-C bond cleavage in CYP51 catalysis. Carbon 83-84 cytochrome P450 family 51 subfamily A member 1 Homo sapiens 104-109 32493730-0 2020 A requirement for an active proton delivery network supports a compound I-mediated C-C bond cleavage in CYP51 catalysis. Carbon 85-86 cytochrome P450 family 51 subfamily A member 1 Homo sapiens 104-109 32039447-7 2020 SDS-PAGE of immunoisolates obtained from TNF-alpha-treated N2a cells by using anti-C-terminal of APP revealed the presence of SDS-stable complexes between HS and the C-terminal fragment of beta-cleaved APP (betaCTF) migrating in the range 10-18 kDa. Carbon 166-167 tumor necrosis factor Mus musculus 41-50 32558533-0 2020 Metal-Organic Frameworks-Derived NiS/Fe3O4 Heterostructure Decorated Carbon Nanotubes as Highly Efficient and Durable Electrocatalyst for Oxygen Evolution Reaction. Carbon 69-75 solute carrier family 5 member 5 Homo sapiens 33-36 32679786-1 2020 Two activated carbons (ACs) were prepared from peat using thermochemical K2SO4 activation at 1053-1133 K for 1h, and steam activation at 1173K for 30 (AC-4) and 45 (AC-6) min. Carbon 14-21 adenylate cyclase 4 Homo sapiens 151-155 32310125-5 2020 The present work aims to study the adsorption of BPA from aqueous solutions onto carbonaceous materials, e.g., a synthesized carbon xerogel (RFX), a chemical-activated carbon from Kraft lignin (KLP) and a commercial activated carbon (F400) for comparative purposes. Carbon 81-87 regulatory factor X1 Homo sapiens 141-144 32310125-5 2020 The present work aims to study the adsorption of BPA from aqueous solutions onto carbonaceous materials, e.g., a synthesized carbon xerogel (RFX), a chemical-activated carbon from Kraft lignin (KLP) and a commercial activated carbon (F400) for comparative purposes. Carbon 125-131 regulatory factor X1 Homo sapiens 141-144 32310125-5 2020 The present work aims to study the adsorption of BPA from aqueous solutions onto carbonaceous materials, e.g., a synthesized carbon xerogel (RFX), a chemical-activated carbon from Kraft lignin (KLP) and a commercial activated carbon (F400) for comparative purposes. Carbon 125-131 regulatory factor X1 Homo sapiens 141-144 32293079-2 2020 Microtubular structures were prepared by template deposition on membrane templates, resulting in functional structures rich in sp and sp2 carbons with highly conjugated pi networks. Carbon 138-145 Sp2 transcription factor Homo sapiens 134-137 32483580-1 2020 Cu oxide-modified CeO2 (CuOx-CeO2) with 2 wt% Cu loading amount was the most effective and reusable heterogeneous catalyst for selective one-pot imine synthesis from methylarenes and anilines via direct oxidation of the sp3 C-H bond in the methylarenes with atmospheric air (0.1 MPa) as an oxidant. Carbon 0-1 Sp3 transcription factor Homo sapiens 220-223 32650596-5 2020 In addition, treatment with kuwanon C reduced cytoplasmic nuclear erythroid 2-related factor (Nrf2) expression and increased Nrf2 expression in the nucleus. Carbon 36-37 nuclear factor, erythroid derived 2, like 2 Mus musculus 94-98 32650596-5 2020 In addition, treatment with kuwanon C reduced cytoplasmic nuclear erythroid 2-related factor (Nrf2) expression and increased Nrf2 expression in the nucleus. Carbon 36-37 nuclear factor, erythroid derived 2, like 2 Mus musculus 125-129 32632125-1 2020 Vitamin B12 (B12) is a micronutrient essential for one-carbon (1C) metabolism. Carbon 55-61 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 8-11 32632125-1 2020 Vitamin B12 (B12) is a micronutrient essential for one-carbon (1C) metabolism. Carbon 55-61 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 13-16 32275243-3 2020 The results showed that cropland expansion led to a massive loss of carbon storage (1.76 Tg C) during 2000-2010, which is expected to continue during 2010-2030 in different scenarios. Carbon 68-74 transglutaminase 2 Homo sapiens 89-93 32635329-0 2020 Detection of Pin Failure in Carbon Fiber Composites Using the Electro-Mechanical Impedance Method. Carbon 28-34 dynein light chain LC8-type 1 Homo sapiens 13-16 32092567-9 2020 Combined with environmental parameters of sediments, redundancy analysis indicated that the nrfA functional gene was positively correlated with moisture content, the concentration of NO2--N and NO3-N; the DNRA rates was positively correlated with sediment organic carbon (SOC), C/NO3- ratio and salinity (ranked by explains %). Carbon 264-270 NBL1, DAN family BMP antagonist Homo sapiens 194-197 32092567-9 2020 Combined with environmental parameters of sediments, redundancy analysis indicated that the nrfA functional gene was positively correlated with moisture content, the concentration of NO2--N and NO3-N; the DNRA rates was positively correlated with sediment organic carbon (SOC), C/NO3- ratio and salinity (ranked by explains %). Carbon 264-270 NBL1, DAN family BMP antagonist Homo sapiens 280-283 32409064-2 2020 BPNSs-G2-beta-CD composite modified glassy carbon electrode (BPNSs-G2-beta-CD/GCE) was further coated with NF which served as a protective film to immobilize BPNSs-G2-beta-CD on the electrode surface to achieve high stability. Carbon 43-49 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 9-16 32662335-3 2020 Composed of sp3-carbon atoms, diamond is chemically inert and inherently biocompatible. Carbon 16-22 Sp3 transcription factor Homo sapiens 12-15 32639961-4 2020 In the current study, we identify two understudied yeast genes, YTA6 and YPR096C that when deleted, cell sensitivity to LiCl is increased when galactose is used as a carbon source. Carbon 166-172 uncharacterized protein Saccharomyces cerevisiae S288C 73-80 31566282-2 2020 Carbon-based nanocages consisting of sp2 carbon shells feature a hollow interior cavity with sub-nanometer microchannels across the shells, high specific surface area with a defective outer surface, and tunable electronic structure, much different from the intensively studied nanocarbons such as carbon nanotubes and graphene. Carbon 0-6 Sp2 transcription factor Homo sapiens 37-40 31566282-2 2020 Carbon-based nanocages consisting of sp2 carbon shells feature a hollow interior cavity with sub-nanometer microchannels across the shells, high specific surface area with a defective outer surface, and tunable electronic structure, much different from the intensively studied nanocarbons such as carbon nanotubes and graphene. Carbon 41-47 Sp2 transcription factor Homo sapiens 37-40 31566282-2 2020 Carbon-based nanocages consisting of sp2 carbon shells feature a hollow interior cavity with sub-nanometer microchannels across the shells, high specific surface area with a defective outer surface, and tunable electronic structure, much different from the intensively studied nanocarbons such as carbon nanotubes and graphene. Carbon 281-287 Sp2 transcription factor Homo sapiens 37-40 32677107-5 2020 In this issue of Molecular Ecology, Rog, Rosenstock, Korner, and Klein (2020) show that closely related trees shared relatively more mycorrhizal fungi than distantly related trees in the same experimental site, which correlated to increased carbon sharing. Carbon 241-247 zinc finger and BTB domain containing 32 Homo sapiens 36-39 32314045-0 2020 Seed-specific down-regulation of Arabidopsis CELLULOSE SYNTHASE 1 or 9 reduces seed cellulose content and differentially affects carbon partitioning. Carbon 129-135 cellulose synthase 1 Arabidopsis thaliana 45-70 32219889-0 2020 Multi-color fluorescent carbon dots: Non-size effect dominate graphitized sp2 conjugated domain and surface state energy level co-modulate band-gap. Carbon 24-30 Sp2 transcription factor Homo sapiens 74-77 32314045-6 2020 In terms of effects on carbon partitioning, AtCESA1 and AtCESA9 RNAi lines exhibited distinct effects. Carbon 23-29 cellulose synthase A9 Arabidopsis thaliana 56-63 32314045-9 2020 Taken together, our results indicate that the seed-specific down-regulation of AtCESA1 causes alterations in seed storage compound accumulation, while the effect of AtCESA9 on carbon partitioning is absent or minor in Arabidopsis. Carbon 176-182 cellulose synthase A9 Arabidopsis thaliana 165-172 32430462-5 2020 Transgenic experiments demonstrated that Gl2-like and Gl2 functionally complement the Arabidopsis cer2 mutation, with differential influences on the cuticular lipids and the lipidome of the plant, particularly affecting the longer alkyl chain acyl lipids, especially at the 32-carbon chain length. Carbon 277-283 Protein ECERIFERUM 26-like Zea mays 41-44 32430462-5 2020 Transgenic experiments demonstrated that Gl2-like and Gl2 functionally complement the Arabidopsis cer2 mutation, with differential influences on the cuticular lipids and the lipidome of the plant, particularly affecting the longer alkyl chain acyl lipids, especially at the 32-carbon chain length. Carbon 277-283 Protein ECERIFERUM 26-like Zea mays 54-57 32390323-2 2020 The fabricated carbon material (named methyl-substituted graphdiyne (MGDY)) comprises sp and sp2 carbons in a conjugated-backbone form, as well as methyl groups introduced into the framework as hydrophobic-enhanced functional groups. Carbon 15-21 Sp2 transcription factor Homo sapiens 93-96 32715699-6 2020 The results showed that during 2005 to 2015, the annual carbon storage, oxygen release, hydrological regulation, water resource, and soil retention in the study area was 0.05 kg C m-2 a-1, 0.13 kg O2 m-2 a-1, 83.25x108 m3 a-1, 803 mm a-1, and 95.53 t hm-2 a-1, respectively. Carbon 56-62 BCL2 related protein A1 Homo sapiens 184-187 32715699-6 2020 The results showed that during 2005 to 2015, the annual carbon storage, oxygen release, hydrological regulation, water resource, and soil retention in the study area was 0.05 kg C m-2 a-1, 0.13 kg O2 m-2 a-1, 83.25x108 m3 a-1, 803 mm a-1, and 95.53 t hm-2 a-1, respectively. Carbon 56-62 BCL2 related protein A1 Homo sapiens 204-207 32715699-6 2020 The results showed that during 2005 to 2015, the annual carbon storage, oxygen release, hydrological regulation, water resource, and soil retention in the study area was 0.05 kg C m-2 a-1, 0.13 kg O2 m-2 a-1, 83.25x108 m3 a-1, 803 mm a-1, and 95.53 t hm-2 a-1, respectively. Carbon 56-62 BCL2 related protein A1 Homo sapiens 204-207 32715699-6 2020 The results showed that during 2005 to 2015, the annual carbon storage, oxygen release, hydrological regulation, water resource, and soil retention in the study area was 0.05 kg C m-2 a-1, 0.13 kg O2 m-2 a-1, 83.25x108 m3 a-1, 803 mm a-1, and 95.53 t hm-2 a-1, respectively. Carbon 56-62 BCL2 related protein A1 Homo sapiens 204-207 32629854-1 2020 Carbon-nanofiber-based screen-printed electrodes modified with silver nanoparticles (Ag-NP-SPCNFEs) were tested in a pioneering manner for the direct determination of As(V) at low mug L-1 levels by means of differential pulse anodic stripping voltammetry. Carbon 0-6 L1 cell adhesion molecule Homo sapiens 184-187 32676099-6 2020 A previous study has found that the polyadenylated tail [poly(A)] deadenylation complex, called Carbon catabolite repressor 4-Negative on TATA (CCR4-NOT) regulates the expression of spookier (spok), which encodes one of the ecdysteroidogenic enzymes in the fruit fly Drosophila melanogaster. Carbon 96-102 twin Drosophila melanogaster 144-148 31968136-1 2020 Freestanding Fe/alpha-ketoglutarate-dependent halogenases are oxidoreductases that catalyze the installation of halogen atoms into unactivated sp3 -hybridized carbon centers with high stereo- and regioselectivity. Carbon 159-165 Sp3 transcription factor Homo sapiens 143-146 32548880-3 2020 Previous studies proposed that compounds containing two aromatic groups connected by a carbon chain should act as effective amyloid beta (Abeta) aggregation inhibitors although the optimal length of the carbon chain has not been explored. Carbon 87-93 amyloid beta precursor protein Homo sapiens 138-143 32548880-3 2020 Previous studies proposed that compounds containing two aromatic groups connected by a carbon chain should act as effective amyloid beta (Abeta) aggregation inhibitors although the optimal length of the carbon chain has not been explored. Carbon 203-209 amyloid beta precursor protein Homo sapiens 138-143 32548880-5 2020 In vitro studies showed that compound 8, which has two aromatic groups connected by a two-carbon chain, exhibited significant inhibition of Abeta aggregation through the prevention of elongation and association of Abeta fibril growth. Carbon 90-96 amyloid beta precursor protein Homo sapiens 140-145 32109798-1 2020 In this work, the influence of oxygen-containing surface groups of activated carbon electrodes on the charge efficiency of electro-assisted adsorption of As(V) was investigated. Carbon 77-83 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 154-159 32213413-4 2020 The present work found that visible-light irradiation promoted the breakdown of sp2 structures of GO by hypochlorite, producing alkanes and arenes with short carbon skeletons. Carbon 158-164 Sp2 transcription factor Homo sapiens 80-83 32217393-6 2020 The formation mechanism of hierarchical porous structure is proposed: co-etching effect of sp2/sp3 hybridized carbon produces micropores and meso-/macropores, respectively. Carbon 110-116 Sp2 transcription factor Homo sapiens 91-94 32217393-6 2020 The formation mechanism of hierarchical porous structure is proposed: co-etching effect of sp2/sp3 hybridized carbon produces micropores and meso-/macropores, respectively. Carbon 110-116 Sp3 transcription factor Homo sapiens 95-98 32599804-3 2020 Here, we report the fabrication of an interdigitated sensing device integrated with polyvinyl alcohol (PVA) nanofibers and carbon nanotubes (CNT) for the detection of an inflammatory biomarker, C-reactive protein (CRP). Carbon 123-129 C-reactive protein Homo sapiens 194-212 32538400-5 2020 For the electronically excited CHF3+ ions, the C-F bond cleavage preferentially occurs to predominantly produce CHF2+ + F. Moreover, all TPEPICO images of the CHF2+ ions exhibit identical patterns, with a weak central spot revealing a previously unobserved statistical decomposition pathway, and the predominant ring in the images documents a fast nonstatistical dissociation channel. Carbon 31-32 hes related family bHLH transcription factor with YRPW motif 1 Homo sapiens 112-116 32538400-5 2020 For the electronically excited CHF3+ ions, the C-F bond cleavage preferentially occurs to predominantly produce CHF2+ + F. Moreover, all TPEPICO images of the CHF2+ ions exhibit identical patterns, with a weak central spot revealing a previously unobserved statistical decomposition pathway, and the predominant ring in the images documents a fast nonstatistical dissociation channel. Carbon 31-32 hes related family bHLH transcription factor with YRPW motif 1 Homo sapiens 159-163 32453309-1 2020 The dynamics of the bimolecular nucleophilic substitution (SN2) reactions at nitrogen are less understood than those of their corresponding reactions at carbon. Carbon 153-159 solute carrier family 38 member 5 Homo sapiens 59-62 32086094-0 2020 Multi-walled carbon nanotubes (MWCNTs) transformed THP-1 macrophages into foam cells: Impact of pulmonary surfactant component dipalmitoylphosphatidylcholine. Carbon 13-19 GLI family zinc finger 2 Homo sapiens 51-56 32086094-3 2020 Recently we found that multi-walled carbon nanotubes (MWCNTs) transformed THP-1 macrophages into lipid-laden foam cells via ER stress pathway. Carbon 36-42 GLI family zinc finger 2 Homo sapiens 74-79 32092656-0 2020 Stable sp2 carbon-conjugated covalent organic framework for detection and efficient adsorption of uranium from radioactive wastewater. Carbon 11-17 Sp2 transcription factor Homo sapiens 7-10 32092656-2 2020 In this work, an ultra-stable sp2 carbon-conjugated covalent organic framework (COF-PDAN-AO) is synthesized with amidoxime-substituted monomers for detection and efficient adsorption of uranium from radioactive wastewater. Carbon 34-40 Sp2 transcription factor Homo sapiens 30-33 32092656-7 2020 These results indicate that our sp2 carbon conjugated COF can be potentially used for practical detection and adsorption of uranium from radioactive wastewater. Carbon 36-42 Sp2 transcription factor Homo sapiens 32-35 32374170-4 2020 These C@Sb NPs can increase active sites for initial sodium nucleation through Sb-Na alloy cores, and keep these cores stable through carbon shells. Carbon 134-140 chorionic somatomammotropin hormone 2 Homo sapiens 6-10 32452472-3 2020 The resulting sp2 + sp3 hybrid network structures have a 24- and 36-atom hexagonal unit cell, termed as (6,0)-hP24 and (9,0)-hP36 carbon, and they topologically correspond to two-dimensional graphyne and graphdiyne. Carbon 130-136 Sp2 transcription factor Homo sapiens 14-17 32452472-3 2020 The resulting sp2 + sp3 hybrid network structures have a 24- and 36-atom hexagonal unit cell, termed as (6,0)-hP24 and (9,0)-hP36 carbon, and they topologically correspond to two-dimensional graphyne and graphdiyne. Carbon 130-136 Sp3 transcription factor Homo sapiens 20-23 32518194-3 2020 Consumption of NO3 - as the sole nitrogen source unexpectedly resulted in more rapid transfer of carbon to heterotrophs than when NH4 + was also provided, suggesting alterations in the form of carbon exchanged. Carbon 97-103 NBL1, DAN family BMP antagonist Homo sapiens 15-18 32518194-3 2020 Consumption of NO3 - as the sole nitrogen source unexpectedly resulted in more rapid transfer of carbon to heterotrophs than when NH4 + was also provided, suggesting alterations in the form of carbon exchanged. Carbon 193-199 NBL1, DAN family BMP antagonist Homo sapiens 15-18 32146425-0 2020 Design a fluorometric aptasensor based on CoOOH nanosheets and carbon dots for simultaneous detection of lysozyme and adenosine triphosphate. Carbon 63-69 lysozyme Homo sapiens 105-113 32162747-0 2020 2D sp2 Carbon-conjugated Porphyrin Covalent Organic Framework for Cooperative Photocatalysis with TEMPO. Carbon 7-13 Sp2 transcription factor Homo sapiens 3-6 32196699-0 2020 Fragmentation at sp2 carbon atoms in fragment molecular orbital method. Carbon 21-27 Sp2 transcription factor Homo sapiens 17-20 32196699-1 2020 In the fragment molecular orbital (FMO) method, a given molecular system is usually fragmented at sp3 carbon atoms. Carbon 102-108 Sp3 transcription factor Homo sapiens 98-101 32196699-3 2020 Hence, we propose fragmentation at sp2 carbon atoms in the FMO method. Carbon 39-45 Sp2 transcription factor Homo sapiens 35-38 32196699-7 2020 Numerical verification shows that the present models are as accurate as or better than the standard FMO2 method in total energy with fragmentation at sp3 carbon atoms. Carbon 154-160 Sp3 transcription factor Homo sapiens 150-153 32401494-3 2020 Herein, we demonstrate that the activity of an Fe/2OG enzyme can be redirected when changing the targeted carbon hybridization from sp3 to sp2. Carbon 106-112 Sp3 transcription factor Homo sapiens 132-135 32401494-3 2020 Herein, we demonstrate that the activity of an Fe/2OG enzyme can be redirected when changing the targeted carbon hybridization from sp3 to sp2. Carbon 106-112 Sp2 transcription factor Homo sapiens 139-142 32109845-3 2020 The native caveolin proteins oxidation mechanism was investigated for the first time, at a glassy carbon electrode, using cyclic, square wave and differential pulse voltammetry. Carbon 98-104 caveolin 1 Homo sapiens 11-19 32248414-6 2020 The model of Avrami is found to be the most appropriate model to represent the adsorption of the pollutant in any of the six modified carbons tested, the highest value of the kinetic constant being 0.055 min-1. Carbon 134-141 CD59 molecule (CD59 blood group) Homo sapiens 204-209 31765230-0 2020 Black Carbon Induces Cytotoxicity and NLRP3 Inflammasome Activation in Human Corneal Epithelial Cells. Carbon 6-12 NLR family pyrin domain containing 3 Homo sapiens 38-43 32277415-1 2020 In this work, lovegrass (Cpa), an abundant grass of the Poaceae family, was employed as feedstock for the production of activated carbon in a conventional furnace using ZnCl2 as a chemical activator. Carbon 130-136 carboxypeptidase A1 Homo sapiens 25-28 32277415-4 2020 FTIR analysis identified the presence of O-H, N-H, O-C=O), C-O, and aromatic ring bulk and surface of (Cpa-AC) adsorbent. Carbon 53-54 carboxypeptidase A1 Homo sapiens 103-106 32393056-2 2020 The present study aims to investigate if common polymorphisms of genes required for one-carbon metabolism (MTHFR, MTRR, MTR and RFC-1) and DNA methylation reactions (DNMT1, DNMT3A and DNMT3B) influence D-loop methylation levels. Carbon 88-94 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 114-118 32274584-4 2020 More recently, fluorine-18-labelled NET tracers have drawn increasing attentions from researchers, due to their longer radiological half-life relative to carbon-11 (110 min vs. 20 min), reduced dependence on on-site cyclotrons, and flexibility in the design of novel tracer structures. Carbon 154-160 solute carrier family 6 member 2 Homo sapiens 36-39 32841189-13 2020 There was a significant decrease in uric acid concentration, pro- (IL-1beta, TNF-alpha) and anti-inflammatory cytokine (IL-10) content after treatment in both groups, but more in patients who received carbon enterosorbent with basic therapy. Carbon 201-207 tumor necrosis factor Homo sapiens 77-86 32302698-3 2020 Cell cultures from 15 controls, 14 asthma and 11 COPD patients were stimulated with IL-13 and poly I:C for 24 h. Co-cultivation of epithelial cells with moMphis and moDCs increased TSLP level only in asthma and the effect of IL-13 and poly I:C stimulation differed in all groups. Carbon 0-1 interleukin 13 Homo sapiens 84-89 31868234-2 2020 Binding of the active vitamin D metabolite, 1,25-dihydroxy vitamin D3 (1,25(OH)2 D3 ) to the vitamin D receptor (VDR) induces conformational changes in its C-terminal domain enabling competency for interaction with physiologically relevant coactivators, including SRC-1. Carbon 156-157 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 264-269 31748038-4 2020 After heat treatment, change in C1s spectra from virgin PAN to oxidized form was detected and sp2 carbon is developed. Carbon 98-104 Sp2 transcription factor Homo sapiens 94-97 32400800-1 2020 Graphene, a single atomic layer of sp2 hybridized carbon, is a promising material for future devices due to its excellent optical and electrical properties. Carbon 50-56 Sp2 transcription factor Homo sapiens 35-38 31811736-4 2020 Significant differences in NO3 - -N concentrations were observed between treatments, with greater removal of NO3 - -N observed in dissolved organic carbon treatments compared to control and particulate organic carbon treatments. Carbon 148-154 NBL1, DAN family BMP antagonist Homo sapiens 109-112 31811736-5 2020 At medium and high flow rates, respectively, dissolved organic carbon treatments resulted in greater NO3 - -N concentration decreases of 31.6% and 27.1% compared to 19% and 11.6% in particulate organic carbon treatments and 18.6% and 17.2% in control treatments. Carbon 63-69 NBL1, DAN family BMP antagonist Homo sapiens 101-104 32279742-3 2020 In this respect, this research work aims to develop heteroatom (N, F, P/B) incorporated multi-walled carbon nanotubes (MWCNT), such as NFP-MWCNT and NFB-MWCNT, which can maximize the wound healing efficacy via destroying the wound pathogen and biofilms. Carbon 101-107 serine peptidase inhibitor, Kunitz type, 2 Rattus norvegicus 70-73 31811736-7 2020 Observed increases in NO3 - -N removal with organic carbon amendments, provides support for continued investigation on improving the efficacy of organic carbon amendments as a best management practice for NO3 - -N removal in agricultural drainage ditches. Carbon 52-58 NBL1, DAN family BMP antagonist Homo sapiens 22-25 31811736-7 2020 Observed increases in NO3 - -N removal with organic carbon amendments, provides support for continued investigation on improving the efficacy of organic carbon amendments as a best management practice for NO3 - -N removal in agricultural drainage ditches. Carbon 52-58 NBL1, DAN family BMP antagonist Homo sapiens 205-208 31811736-7 2020 Observed increases in NO3 - -N removal with organic carbon amendments, provides support for continued investigation on improving the efficacy of organic carbon amendments as a best management practice for NO3 - -N removal in agricultural drainage ditches. Carbon 153-159 NBL1, DAN family BMP antagonist Homo sapiens 22-25 32427846-4 2020 Extensive mechanistic studies suggest that the localized spin densities at sp2 carbons of alkenes account for the productive sensitization of alkenes despite their similar triplet levels of alkenes and alkynes. Carbon 79-86 Sp2 transcription factor Homo sapiens 75-78 32581424-2 2020 Here, we designed a -SO3H functionalized polyphenylene (PPhen) framework with purely sp2-hybridized carbons, which exhibited high activity in the hydration of alkynes including challenging aliphatic substrates such as 1-octyne. Carbon 100-107 Sp2 transcription factor Homo sapiens 85-88 32612487-2 2020 In established ionic processes, the boron ate complex is activated by an external electrophile to induce a 1,2-migration from boron to an adjacent sp 3 or sp 2 carbon atom. Carbon 160-166 Sp3 transcription factor Homo sapiens 147-151 32612487-2 2020 In established ionic processes, the boron ate complex is activated by an external electrophile to induce a 1,2-migration from boron to an adjacent sp 3 or sp 2 carbon atom. Carbon 160-166 Sp2 transcription factor Homo sapiens 155-159 32612487-3 2020 Recently, two complementary radical polar crossover approaches have been explored for both classes, 1,2-migrations to sp 2 and sp 3 carbon centers. Carbon 132-138 Sp2 transcription factor Homo sapiens 118-131 32239160-4 2020 Simultaneously, compared with X-ray radiation, carbon ion radiation induced a marked increase in Bax and prominent decreases in cyclin B1 and Bcl-2 in a dose-dependent manner. Carbon 47-53 BCL2 associated X, apoptosis regulator Homo sapiens 97-100 32239160-4 2020 Simultaneously, compared with X-ray radiation, carbon ion radiation induced a marked increase in Bax and prominent decreases in cyclin B1 and Bcl-2 in a dose-dependent manner. Carbon 47-53 BCL2 apoptosis regulator Homo sapiens 142-147 32239160-5 2020 Furthermore, the Akt/mTOR/p70S6K pathway was significantly inhibited by carbon ion radiation in both breast cancer cell lines. Carbon 72-78 AKT serine/threonine kinase 1 Homo sapiens 17-20 32239160-5 2020 Furthermore, the Akt/mTOR/p70S6K pathway was significantly inhibited by carbon ion radiation in both breast cancer cell lines. Carbon 72-78 mechanistic target of rapamycin kinase Homo sapiens 21-25 32239160-6 2020 These results indicate that carbon ion radiation kills MDA-MB-231 and MCF-7 breast cancer cells more effectively than X-ray radiation, which might result from the inhibition of the Akt/mTOR/p70S6K pathway. Carbon 28-34 AKT serine/threonine kinase 1 Homo sapiens 181-184 32239160-6 2020 These results indicate that carbon ion radiation kills MDA-MB-231 and MCF-7 breast cancer cells more effectively than X-ray radiation, which might result from the inhibition of the Akt/mTOR/p70S6K pathway. Carbon 28-34 mechanistic target of rapamycin kinase Homo sapiens 185-189 32329614-0 2020 Part 1: Cost Analysis of Carbon Capture and Sequestration from U.S. Natural Gas-fired Power Plants. Carbon 25-31 PAXIP1 associated glutamate rich protein 1 Homo sapiens 76-79 32415176-1 2020 Penta-graphene is a quasi-two-dimensional carbon allotrope consisting of a pentagonal lattice in which both sp2 and sp3-like carbons are present. Carbon 125-132 Sp3 transcription factor Homo sapiens 116-119 32499803-4 2020 Under normoxia, AOX was important to maintain respiratory carbon flow, to prevent the mitochondrial generation of superoxide and nitric oxide (NO), to control lipid peroxidation and protein S-nitrosylation, and possibly to reduce the inhibition of cyt oxidase by NO. Carbon 58-64 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 16-19 32499803-8 2020 The amount of inactivation of mitochondrial aconitase during hypoxia was also dependent upon AOX amount, perhaps through its effects on NO amount, and this influenced carbon flow under hypoxia. Carbon 167-173 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 93-96 32435713-0 2020 Synthesis of bovine serum albumin capped boron-doped carbon dots for sensitive and selective detection of Pb(II) ion. Carbon 53-59 albumin Homo sapiens 20-33 32435713-0 2020 Synthesis of bovine serum albumin capped boron-doped carbon dots for sensitive and selective detection of Pb(II) ion. Carbon 53-59 submaxillary gland androgen regulated protein 3B Homo sapiens 106-112 32435713-4 2020 The surface of boron doped carbon dots is capped with bovine serum albumin. Carbon 27-33 albumin Homo sapiens 61-74 32443416-3 2020 In vitro, increased TNF-alpha and IL-1ss cytokine mRNA expression was observed in Nano-11-KAg-poly(I:C)-treated porcine monocyte-derived dendritic cells. Carbon 101-103 tumor necrosis factor Homo sapiens 20-29 32088441-2 2020 Herein, three-dimensional (3D) needled carbon fiber felts reinforced silicon oxycarbide (SiOC/CFs) composites with excellent electromagnetic (EM) wave absorption, good oxidation resistance and mechanical properties were successfully prepared through a simple precursor infiltration and pyrolysis (PIP) process. Carbon 39-45 prolactin induced protein Homo sapiens 297-300 32088441-5 2020 The minimum reflection loss (RLmin) of pure carbon fiber felts is -8.4 dB, whose value is decreased to -62.9 dB for the composites with 1 PIP cycle, and to -49.9 dB for the composites with 2 PIP cycles, respectively. Carbon 44-50 prolactin induced protein Homo sapiens 191-194 32323547-3 2020 Various valuable 1,2-dicarbonyl derivatives attached to an indolizine core were easily accessed by the direct dicarbonylation of the sp2 C-H bond. Carbon 137-138 Sp2 transcription factor Homo sapiens 133-136 32415176-5 2020 Our results show that this doping can induce semiconductor, semimetallic, or metallic behavior depending on the doping atom and targeted hybridization (sp2 or sp3-like carbons). Carbon 168-175 Sp3 transcription factor Homo sapiens 159-162 32415176-6 2020 In particular, we observed that nitrogen doping of sp2-like carbons atoms can produce a bandgap modulation between semimetallic and semiconductor behavior. Carbon 60-67 Sp2 transcription factor Homo sapiens 51-54 32352121-2 2020 The hybrid film combines the dual advantages of sp2 (carbon nanograss) and sp3 (nanocrystalline diamond) bonded carbon, possessing not only the excellent electrical characteristics of sp2 carbon but also the exceptional electrochemical stability of sp3 carbon. Carbon 112-118 Sp3 transcription factor Homo sapiens 75-78 32129408-1 2020 We present multiple-bent multi-walled carbon nanotubes (MWCNTs) that enable the picomolar detection of C-reactive protein (CRP), which is considered to be a promising biomarker for various diseases. Carbon 38-44 C-reactive protein Homo sapiens 103-121 32129408-1 2020 We present multiple-bent multi-walled carbon nanotubes (MWCNTs) that enable the picomolar detection of C-reactive protein (CRP), which is considered to be a promising biomarker for various diseases. Carbon 38-44 C-reactive protein Homo sapiens 123-126 32352121-2 2020 The hybrid film combines the dual advantages of sp2 (carbon nanograss) and sp3 (nanocrystalline diamond) bonded carbon, possessing not only the excellent electrical characteristics of sp2 carbon but also the exceptional electrochemical stability of sp3 carbon. Carbon 112-118 Sp2 transcription factor Homo sapiens 184-187 32352121-2 2020 The hybrid film combines the dual advantages of sp2 (carbon nanograss) and sp3 (nanocrystalline diamond) bonded carbon, possessing not only the excellent electrical characteristics of sp2 carbon but also the exceptional electrochemical stability of sp3 carbon. Carbon 112-118 Sp3 transcription factor Homo sapiens 75-78 32352121-2 2020 The hybrid film combines the dual advantages of sp2 (carbon nanograss) and sp3 (nanocrystalline diamond) bonded carbon, possessing not only the excellent electrical characteristics of sp2 carbon but also the exceptional electrochemical stability of sp3 carbon. Carbon 112-118 Sp2 transcription factor Homo sapiens 184-187 32352121-2 2020 The hybrid film combines the dual advantages of sp2 (carbon nanograss) and sp3 (nanocrystalline diamond) bonded carbon, possessing not only the excellent electrical characteristics of sp2 carbon but also the exceptional electrochemical stability of sp3 carbon. Carbon 112-118 Sp3 transcription factor Homo sapiens 75-78 32352121-2 2020 The hybrid film combines the dual advantages of sp2 (carbon nanograss) and sp3 (nanocrystalline diamond) bonded carbon, possessing not only the excellent electrical characteristics of sp2 carbon but also the exceptional electrochemical stability of sp3 carbon. Carbon 112-118 Sp2 transcription factor Homo sapiens 184-187 32155086-2 2020 The voltage between the inner channel of curved sp2 carbon nanostructures and their surroundings scales linearly with nanotube wall curvature and can be boosted/reversed by appropriate outer wall functionalization. Carbon 52-58 Sp2 transcription factor Homo sapiens 48-51 32267704-4 2020 The diaphite nanocomposites represent a new class of high-performance carbon materials that are predicted to combine the superhard qualities of diamond with high fracture toughness and ductility enabled by the graphitic units and the atomically defined interfaces between the sp3- and sp2-bonded nanodomains. Carbon 70-76 Sp3 transcription factor Homo sapiens 276-279 32267704-4 2020 The diaphite nanocomposites represent a new class of high-performance carbon materials that are predicted to combine the superhard qualities of diamond with high fracture toughness and ductility enabled by the graphitic units and the atomically defined interfaces between the sp3- and sp2-bonded nanodomains. Carbon 70-76 Sp2 transcription factor Homo sapiens 285-288 32271545-6 2020 Furthermore, combined with intermediates detected by liquid chromatography quadrupole time-of-flight mass spectrometry and density functional theory calculation results, the degradation pathway of BP-4 involving hydroxylation and C-C bond cleavage was proposed. Carbon 230-231 BP4 Homo sapiens 197-201 32394193-3 2020 Au nanoparticles were loaded on COF-LZUl to immobilise the CRP antibody (anti-CRP) on the surface of a glassy carbon electrode. Carbon 110-116 C-reactive protein Homo sapiens 59-62 32394193-3 2020 Au nanoparticles were loaded on COF-LZUl to immobilise the CRP antibody (anti-CRP) on the surface of a glassy carbon electrode. Carbon 110-116 C-reactive protein Homo sapiens 78-81 32394193-5 2020 The as-synthesised activated carbon-supported bimetallic Pt/Ru/C nanoparticle composite was used to label secondary CRP antibody because it exhibited excellent catalytic behaviour toward hydrogen peroxide. Carbon 29-35 C-reactive protein Homo sapiens 116-119 32319500-1 2020 Bulky sp2-carbon Schwarzites with negative Gaussian curvature are promising structures for practical applications due to their unique properties such as high surface area, large porosity, and stability against graphitization. Carbon 10-16 Sp2 transcription factor Homo sapiens 6-9 32415123-0 2020 Synergy between the anthocyanin and RDR6/SGS3/DCL4 siRNA pathways expose hidden features of Arabidopsis carbon metabolism. Carbon 104-110 dicer-like 4 Arabidopsis thaliana 46-50 32415123-4 2020 We show that mutations in RDR6, SGS3, or DCL4 suppress the anthocyanin defect of tt19 by pushing carbon towards flavonoid biosynthesis. Carbon 97-103 dicer-like 4 Arabidopsis thaliana 41-45 32271545-6 2020 Furthermore, combined with intermediates detected by liquid chromatography quadrupole time-of-flight mass spectrometry and density functional theory calculation results, the degradation pathway of BP-4 involving hydroxylation and C-C bond cleavage was proposed. Carbon 232-233 BP4 Homo sapiens 197-201 31958511-6 2020 Further study showed that TRIM7 interacted with p65 via its C-terminal which is different from GNIP1. Carbon 60-61 tripartite motif containing 7 Homo sapiens 26-31 32087542-1 2020 Heterotrophic denitrification using mariculture solid wastes (MSW) fermentation liquid as carbon source is an economically and environmentally sustainable strategy for NO3--N removal in marine recycling aquaculture systems (RAS). Carbon 90-96 NBL1, DAN family BMP antagonist Homo sapiens 168-171 32087542-3 2020 The optimum C/N of 8 and HRT of 6 h for heterotrophic denitrification was obtained with NO3--N removal efficiency of 97.8% and 94.2%, respectively. Carbon 12-13 NBL1, DAN family BMP antagonist Homo sapiens 88-91 32477294-2 2020 Here, we show that in the fungus Aspergillus nidulans the lack of Drp1 and Fis-1 homologs DnmA and FisA has strong developmental defects, leading to a notable decrease in hyphal growth and asexual and sexual sporulation, with some of these defects being aggravated or partially remediated by different carbon sources. Carbon 302-308 Fis1p Saccharomyces cerevisiae S288C 75-80 32058911-2 2020 Results showed that MEC-AGS yielded a higher proportion of CH4 than MEC (83.8 +- 0.4% vs 82.0 +- 1.0%, P < 0.05) with sodium acetate (NaAc) as the only carbon source. Carbon 155-161 C-C motif chemokine ligand 28 Homo sapiens 20-23 31818358-6 2020 Moreover, the C-terminal region (296-414 residues) of YY1 is responsible for the transcriptional upregulation, which could be enhanced further in the presence of the viral Tat protein. Carbon 14-15 YY1 transcription factor Homo sapiens 54-57 31958511-3 2020 However, it is very interesting that TRIM7, the shortest isoform, only 15 amino acids different from GNIP1 in C-terminal, acts in a completely different way from that of GNIP1 in our present study. Carbon 110-111 tripartite motif containing 7 Homo sapiens 37-42 32016283-2 2020 Platelet SFKs are inhibited by C-terminal Src kinase (Csk), which phosphorylates a conserved tyrosine in their C-terminal tail, and are activated by the receptor-type tyrosine phosphatase PTPRJ (CD148, DEP-1), which dephosphorylates the same residue. Carbon 31-32 c-src tyrosine kinase Mus musculus 54-57 32364266-0 2020 Sulphur doped carbon dots enhance photodynamic therapy via PI3K/Akt signalling pathway. Carbon 14-20 AKT serine/threonine kinase 1 Homo sapiens 64-67 32126245-8 2020 By using this model, we demonstrated that MDA5-IPS1-TRAF6-NFkappaB-cytokines, MDA5-IPS1-TRAF3-IRF3-interferon or TLR22-TRIF-IRF3-interferon, TLR8-MyD88-NFkappaB-cytokines, and TLR3-TRIF-IRF3-interferon pathways were able to response to poly I: C challenge in the muscle cell line of large yellow croaker. Carbon 244-245 interferon-induced helicase C domain-containing protein 1 Larimichthys crocea 42-46 32126245-8 2020 By using this model, we demonstrated that MDA5-IPS1-TRAF6-NFkappaB-cytokines, MDA5-IPS1-TRAF3-IRF3-interferon or TLR22-TRIF-IRF3-interferon, TLR8-MyD88-NFkappaB-cytokines, and TLR3-TRIF-IRF3-interferon pathways were able to response to poly I: C challenge in the muscle cell line of large yellow croaker. Carbon 244-245 TNF receptor-associated factor 6 Larimichthys crocea 52-57 31988475-2 2020 In Streptococcus sanguinis SK36 (SK36) and Streptococcus gordonii DL1 (DL1), spxB expression and H2O2 release are subject to carbon catabolite repression by the catabolite control protein A (CcpA). Carbon 125-131 pyruvate oxidase Streptococcus sanguinis SK36 77-81 31988475-2 2020 In Streptococcus sanguinis SK36 (SK36) and Streptococcus gordonii DL1 (DL1), spxB expression and H2O2 release are subject to carbon catabolite repression by the catabolite control protein A (CcpA). Carbon 125-131 catabolite control protein A Streptococcus sanguinis SK36 191-195 31968132-12 2020 Both intact and C-terminal FGF23 were significantly elevated in WNT1 mutation-positive subjects (p=0.039 and 0.027, respectively) and normal in PLS3 subjects. Carbon 16-17 Wnt family member 1 Homo sapiens 64-68 32204042-12 2020 It revealed that the pro-inflammatory cytokines (TNF-alpha and IL-1beta) were significantly upregulated on PCL nanofibers, while their expression was comparatively lower on poly-l-lysine coated PCL or PVP-I/PCL(c/s) nanofibers. Carbon 38-39 tumor necrosis factor Mus musculus 49-58 32110848-6 2020 Brain 1-carbon metabolites, body weight, food intake, energy expenditure, plasma hormones, and protein expression of hypothalamic neuropeptides are measured. Carbon 8-14 POU class 3 homeobox 3 Rattus norvegicus 0-7 32016283-2 2020 Platelet SFKs are inhibited by C-terminal Src kinase (Csk), which phosphorylates a conserved tyrosine in their C-terminal tail, and are activated by the receptor-type tyrosine phosphatase PTPRJ (CD148, DEP-1), which dephosphorylates the same residue. Carbon 31-32 protein tyrosine phosphatase, receptor type, J Mus musculus 188-193 32016283-2 2020 Platelet SFKs are inhibited by C-terminal Src kinase (Csk), which phosphorylates a conserved tyrosine in their C-terminal tail, and are activated by the receptor-type tyrosine phosphatase PTPRJ (CD148, DEP-1), which dephosphorylates the same residue. Carbon 31-32 protein tyrosine phosphatase, receptor type, J Mus musculus 195-200 32365872-3 2020 In this work, we estimate the dissociation constant of both of them by means of a direct assay on magnetic beads modified with AFP and electrochemical detection on carbon screen-printed electrodes (SPCE). Carbon 164-170 alpha fetoprotein Homo sapiens 127-130 32239073-2 2020 While beta3-amino acids can be readily prepared from alpha-amino acids via one-carbon homologation, the synthesis of beta2-amino acids generally requires multistep efforts. Carbon 79-85 immunoglobulin kappa variable 2D-28 Homo sapiens 6-11 32267268-2 2020 However, due to the coexistence of sp and sp2 carbon atoms in graphyne, some factors playing important roles in determining the ORR activity have received little attention. Carbon 46-52 Sp2 transcription factor Homo sapiens 42-45 32314017-3 2020 When lysozyme was added, the aptamer specifically binds to the lysozyme, causing the signal tag to detach from the magnetic carboxylated carbon nanotubes. Carbon 137-143 lysozyme Homo sapiens 5-13 32342229-5 2020 The downregulated DEGs were significantly enriched for biosynthesis of antibiotics, carbon metabolism and protein digestion, while the upregulated DEGs were mainly enriched for cancer and PI3K-Akt signaling pathway. Carbon 84-90 AKT serine/threonine kinase 1 Homo sapiens 193-196 32233362-3 2020 However, direct use of arenes and alkanes via a twofold oxidative C-H bond activation strategy to access chemoselective C(sp2)-C(sp3) cross-couplings is highly challenging due to the low reactivity of carbon-hydrogen (C-H) bonds and the difficulty in suppressing side reactions such as homocouplings. Carbon 201-207 Sp2 transcription factor Homo sapiens 120-125 32377162-10 2020 Hyperresponsiveness to poly (I:C) in TNIP1-deficient keratinocytes was in part mediated through p38 and JNK pathways. Carbon 31-33 TNFAIP3 interacting protein 1 Homo sapiens 37-42 32377162-10 2020 Hyperresponsiveness to poly (I:C) in TNIP1-deficient keratinocytes was in part mediated through p38 and JNK pathways. Carbon 31-33 mitogen-activated protein kinase 14 Homo sapiens 96-99 32377162-10 2020 Hyperresponsiveness to poly (I:C) in TNIP1-deficient keratinocytes was in part mediated through p38 and JNK pathways. Carbon 31-33 mitogen-activated protein kinase 8 Homo sapiens 104-107 32264767-3 2021 The addition of 0.5 g L-1 zeolite to a continuously-fed membrane photobioreactor increased the microalgal biomass concentration from 0.50 to 0.90-1.17 g particulate organic carbon per L while the average ammonium removal efficiency increased from 14% to 30%. Carbon 173-179 L1 cell adhesion molecule Homo sapiens 22-25 32312976-4 2020 Here we show that a decline of 0.2 +- 0.1 PgC yr-1 in fire emissions during 2008-2014 relative to 2001-2007 also induced an additional carbon sink enhancement of 0.4 +- 0.2 PgC yr-1 attributable to carbon cycle feedbacks, amounting to a combined sink increase comparable to the 0.6 PgC yr-1 budget imbalance. Carbon 135-141 progastricsin Homo sapiens 42-45 32312976-4 2020 Here we show that a decline of 0.2 +- 0.1 PgC yr-1 in fire emissions during 2008-2014 relative to 2001-2007 also induced an additional carbon sink enhancement of 0.4 +- 0.2 PgC yr-1 attributable to carbon cycle feedbacks, amounting to a combined sink increase comparable to the 0.6 PgC yr-1 budget imbalance. Carbon 135-141 progastricsin Homo sapiens 173-176 32312976-4 2020 Here we show that a decline of 0.2 +- 0.1 PgC yr-1 in fire emissions during 2008-2014 relative to 2001-2007 also induced an additional carbon sink enhancement of 0.4 +- 0.2 PgC yr-1 attributable to carbon cycle feedbacks, amounting to a combined sink increase comparable to the 0.6 PgC yr-1 budget imbalance. Carbon 135-141 progastricsin Homo sapiens 173-176 32312976-4 2020 Here we show that a decline of 0.2 +- 0.1 PgC yr-1 in fire emissions during 2008-2014 relative to 2001-2007 also induced an additional carbon sink enhancement of 0.4 +- 0.2 PgC yr-1 attributable to carbon cycle feedbacks, amounting to a combined sink increase comparable to the 0.6 PgC yr-1 budget imbalance. Carbon 198-204 progastricsin Homo sapiens 42-45 32312976-4 2020 Here we show that a decline of 0.2 +- 0.1 PgC yr-1 in fire emissions during 2008-2014 relative to 2001-2007 also induced an additional carbon sink enhancement of 0.4 +- 0.2 PgC yr-1 attributable to carbon cycle feedbacks, amounting to a combined sink increase comparable to the 0.6 PgC yr-1 budget imbalance. Carbon 198-204 progastricsin Homo sapiens 173-176 32312976-4 2020 Here we show that a decline of 0.2 +- 0.1 PgC yr-1 in fire emissions during 2008-2014 relative to 2001-2007 also induced an additional carbon sink enhancement of 0.4 +- 0.2 PgC yr-1 attributable to carbon cycle feedbacks, amounting to a combined sink increase comparable to the 0.6 PgC yr-1 budget imbalance. Carbon 198-204 progastricsin Homo sapiens 173-176 32314017-3 2020 When lysozyme was added, the aptamer specifically binds to the lysozyme, causing the signal tag to detach from the magnetic carboxylated carbon nanotubes. Carbon 137-143 lysozyme Homo sapiens 63-71 32314017-5 2020 The released lysozyme can be recombined with the signal tag adsorbed on the magnetic carboxylated carbon nanotube, allowing more signal tag to be dispersed into the solution. Carbon 98-104 lysozyme Homo sapiens 13-21 32237752-2 2020 The reaction proceeds by the condensation of two molecules of fumaronitrile and one molecule of 1,3-diketone in a remarkable process that involves the cleavage of one C(sp3)-C(sp2) bond in 1,3-diketones and the formation of one carbon-nitrogen bond and four carbon-carbon bonds to construct both the aryl and pyrrole rings of the indole in one step. Carbon 228-234 Sp2 transcription factor Homo sapiens 174-179 32325787-2 2020 The aim is to access the capacity of carbon thin films, with different contents of sp2 and sp1 bonds, to act as a solid lubricant for copper surfaces. Carbon 37-43 Sp2 transcription factor Homo sapiens 83-86 32325861-1 2020 A metastable sp3-bonded carbon allotrope, Penta-C20, consisting entirely of carbon pentagons linked through bridge-like bonds, was proposed and studied in this work for the first time. Carbon 24-30 Sp3 transcription factor Homo sapiens 13-16 32325861-1 2020 A metastable sp3-bonded carbon allotrope, Penta-C20, consisting entirely of carbon pentagons linked through bridge-like bonds, was proposed and studied in this work for the first time. Carbon 76-82 Sp3 transcription factor Homo sapiens 13-16 32321025-7 2020 Our work confirm other estimates of biomass 39 Mg/ha (9-61 Mg/ha) and carbon 0.79 PgC. Carbon 70-76 progastricsin Homo sapiens 82-85 32237752-2 2020 The reaction proceeds by the condensation of two molecules of fumaronitrile and one molecule of 1,3-diketone in a remarkable process that involves the cleavage of one C(sp3)-C(sp2) bond in 1,3-diketones and the formation of one carbon-nitrogen bond and four carbon-carbon bonds to construct both the aryl and pyrrole rings of the indole in one step. Carbon 258-264 Sp2 transcription factor Homo sapiens 174-179 32237752-2 2020 The reaction proceeds by the condensation of two molecules of fumaronitrile and one molecule of 1,3-diketone in a remarkable process that involves the cleavage of one C(sp3)-C(sp2) bond in 1,3-diketones and the formation of one carbon-nitrogen bond and four carbon-carbon bonds to construct both the aryl and pyrrole rings of the indole in one step. Carbon 258-264 Sp2 transcription factor Homo sapiens 174-179 32204673-9 2021 In the optimal conditions (FH2O2 = 3.27 mmol min-1 and [Fe2+] = 0.27 mmol L-1), the photo-Fenton process achieved a percentage of organic carbon removal of 84%, in only 30 minutes of reaction, presenting an interesting potential for real industrial applications, combined, or not, with conventional technologies (as biological treatments, for example). Carbon 138-144 CD59 molecule (CD59 blood group) Homo sapiens 45-50 32236264-3 2020 The results reveal that molecules (employed in OLEDs) with basic units containing C(sp2)-N(sp3) bonds (nitrogen connected to carbon in a triangular fashion) have a natural tendency to fragment at the C-N bond through an S1/S0 conical intersection (CI). Carbon 125-131 Sp2 transcription factor Homo sapiens 82-87 32056967-5 2020 The super-sensitive colorimetric process produced linear regression equation for H2O2 as A = 0.00105C + 0.0630 (C:muM, R2 = 0.9961) with a detection limit of 0.052 muM, whereas for glucose, the linear relationship was A = 0.00084C + 0.0458 (C:muM, R2 = 0.9952) having a detection limit of 0.055 muM. Carbon 224-230 latexin Homo sapiens 114-117 32056967-5 2020 The super-sensitive colorimetric process produced linear regression equation for H2O2 as A = 0.00105C + 0.0630 (C:muM, R2 = 0.9961) with a detection limit of 0.052 muM, whereas for glucose, the linear relationship was A = 0.00084C + 0.0458 (C:muM, R2 = 0.9952) having a detection limit of 0.055 muM. Carbon 224-230 latexin Homo sapiens 164-167 32056967-5 2020 The super-sensitive colorimetric process produced linear regression equation for H2O2 as A = 0.00105C + 0.0630 (C:muM, R2 = 0.9961) with a detection limit of 0.052 muM, whereas for glucose, the linear relationship was A = 0.00084C + 0.0458 (C:muM, R2 = 0.9952) having a detection limit of 0.055 muM. Carbon 224-230 latexin Homo sapiens 164-167 32056967-5 2020 The super-sensitive colorimetric process produced linear regression equation for H2O2 as A = 0.00105C + 0.0630 (C:muM, R2 = 0.9961) with a detection limit of 0.052 muM, whereas for glucose, the linear relationship was A = 0.00084C + 0.0458 (C:muM, R2 = 0.9952) having a detection limit of 0.055 muM. Carbon 224-230 latexin Homo sapiens 164-167 31848088-5 2020 The Fe3O4-g-CN@PEI-beta-CD NC exhibited fast adsorption rates towards TC and maximum adsorption capacity on the basis of the Langmuir model reached 833.33 mg g-1, much higher than that reported by different carbon- and/or nano-based materials. Carbon 207-213 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 19-26 32287294-8 2020 In a cell line representing HER2-overexpressing tumor subtype an elevated expression of TG (<= C-46), phosphatidylcholines (PC) and PE containing short-chained (<= C-16) saturated or monounsaturated fatty acids were observed. Carbon 95-96 erb-b2 receptor tyrosine kinase 2 Homo sapiens 28-32 32287294-8 2020 In a cell line representing HER2-overexpressing tumor subtype an elevated expression of TG (<= C-46), phosphatidylcholines (PC) and PE containing short-chained (<= C-16) saturated or monounsaturated fatty acids were observed. Carbon 125-126 erb-b2 receptor tyrosine kinase 2 Homo sapiens 28-32 32362781-2 2020 Analyses of the Au(I)-C bond in [(NHC)AuL]+/0 (L stands for a neutral or negatively charged ligand), through the Dewar-Chatt-Duncanson model and the charge displacement function, have revealed that NHC is not purely a sigma-donor but may have a significant pi-acceptor character. Carbon 22-23 high mobility group nucleosomal binding domain 4 Homo sapiens 34-37 32435375-4 2020 The seven-carbon linker (compound 15c) was optimal for inhibition of both CK2 and HDAC1. Carbon 10-16 histone deacetylase 1 Homo sapiens 82-87 32062971-3 2020 6:2 FTS was simultaneously transformed to perfluoroalkyl carboxylic acids (C2-C7 PFCAs) of different chain length, with perfluorohexanoic acid (C6) as the predominant one. Carbon 144-146 AKT interacting protein Homo sapiens 4-7 32062971-8 2020 Density functional theory calculations showed that OH oxidizes 6:2 FTS by H-abstraction from the ethyl carbons. Carbon 98-111 AKT interacting protein Homo sapiens 68-71 32182420-2 2020 Spontaneous nanoscale oxidation of surface-abundant nitroso-/nitro- functionalities leads to two distinctly colored carbon dots (CD) which are isolated by polarity driven chromatographic separation. Carbon 116-122 BCL10, immune signaling adaptor Rattus norvegicus 129-131 32182420-9 2020 FI of this conjugated carbon dot, rCD-GAPDH was also found to decrease in presence of Ca2+ and varied in relation to H+ concentrations and could serve as a tool to quantify the intracellular concentrations of Ca2+ and pH value (H+) which can give important information about cell survival. Carbon 22-28 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 38-43 31989122-3 2020 In particular, we show that the initial phase of the degradation involves the transformation of an alkane-type C-C bond into an alkene-type C[double bond, length as m-dash]C bond in the PFAS molecule, which is initiated by the trans elimination of fluorine atoms bonded to these adjacent carbon atoms. Carbon 288-294 phosphoribosylformylglycinamidine synthase Homo sapiens 186-190 32133856-3 2020 Different sp3 carbon-bearing carboxylic acids were successfully employed as substrates, including phenylacetic acid-type substrates, as well as aliphatic carboxylic acids. Carbon 14-20 Sp3 transcription factor Homo sapiens 10-13 31612430-3 2020 The activity of the CAT effector module is controlled by antagonist phosphorylations by the phosphotransferase system on conserved histidines of the two C-terminal PRDs in response to available carbon sources. Carbon 194-200 catalase Homo sapiens 20-23 32162086-0 2020 PtNPs-GNPs-MWCNTs-beta-CD nanocomposite modified glassy carbon electrode for sensitive electrochemical detection of folic acid. Carbon 56-62 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 18-25 32163660-1 2020 Freeze casting, also known as ice templating, is a particularly versatile technique that has been applied extensively for the fabrication of well-controlled biomimetic porous materials based on ceramics, metals, polymers, biomacromolecules, and carbon nanomaterials, endowing them with novel properties and broadening their applicability. Carbon 245-251 carboxylesterase 2 Homo sapiens 30-33 32073757-4 2020 To overcome these obstacles, copeptin, the C-terminal fragment stemming from the ADH precursor, has been increasingly used as a stable clinical measure for ADH. Carbon 43-44 arginine vasopressin Homo sapiens 29-37 32072453-3 2020 Rpn12 contains a N-terminal TPR (tetratrico peptide repeat)-like domain and a C-terminal WH (winged helix) domain. Carbon 78-79 proteasome regulatory particle lid subunit RPN12 Saccharomyces cerevisiae S288C 0-5 31962067-6 2020 Upon DNA binding, the C-terminal last helix of XPA would shift towards the minor groove of the DNA substrate for better interaction. Carbon 22-23 XPA, DNA damage recognition and repair factor Homo sapiens 47-50 32328942-0 2020 Combined Administration of TLR4 (LPS) and TLR3 (Poly I:C) Ligands to CBA Mice Elevates the Content of Osteogenic MSC by 1.6 Times and Increases Content of Bone Marrow MSC to Intermediate Level between Values Attained by Their Individual Administration. Carbon 0-1 toll-like receptor 4 Mus musculus 27-31 32086168-2 2020 In rare cases, the dAdo radical can add to a sp2 carbon to result in the production an adenosylated product. Carbon 49-55 Sp2 transcription factor Homo sapiens 45-48 32023802-5 2020 The C10 and C11 groups were the predominant carbon groups in all the samples. Carbon 44-50 homeobox C10 Homo sapiens 4-7 31997245-8 2020 The major policy inference from this study is that expansion of trade or increase in trade openness as suggest by Environmental Kuznets curve phenomenon will reduce the emission of carbon in MENA region in the long run. Carbon 181-187 ENAH actin regulator Homo sapiens 191-195 31997245-11 2020 Energy consumption is found to increase the emission of carbon in the region; thus, there is need to ensure implementation of policies designed to secure efficient energy use and energy supply at the same actualizing the target of having supportable environment and enlargement of MENA nations" far-reaching projects in renewable energy. Carbon 56-62 ENAH actin regulator Homo sapiens 281-285 32433029-0 2020 High-performance immunosensor for urine albumin using hybrid architectures of ZnO nanowire/carbon nanotube. Carbon 91-97 albumin Homo sapiens 40-47 32433029-1 2020 In this work, the authors reported the hybrid architecture of carbon nanotube (CNT)-zinc oxide (ZnO) nanowire as a multi-functional probe in amperometric immunosensor for the detection of urine albumin. Carbon 62-68 albumin Homo sapiens 194-201 31919735-0 2020 Correction to: Phosphomimetic Mutation of Glycine Transporter GlyT1 C-Terminal PDZ Binding Motif Inhibits its Interactions with PSD95. Carbon 0-1 solute carrier family 6 member 9 Homo sapiens 62-67 31935586-2 2020 Ag nanoparticles were employed in freestanding and binder-free F-GNS electrode (the composite film electrode was labeled as FGA) as catalyst, which were shown to strongly facilitate the decomposition of NaF during charge process in sodium/carbon fluorides (Na/CFx) secondary batteries. Carbon 239-255 fibrinogen alpha chain Homo sapiens 124-127 31935586-2 2020 Ag nanoparticles were employed in freestanding and binder-free F-GNS electrode (the composite film electrode was labeled as FGA) as catalyst, which were shown to strongly facilitate the decomposition of NaF during charge process in sodium/carbon fluorides (Na/CFx) secondary batteries. Carbon 239-255 C-X-C motif chemokine ligand 8 Homo sapiens 203-206 32096912-2 2020 Herein, a sp2 carbon-conjugated covalent triazine polymer (sp2 c-CTP-4), featuring a vinylene bridge and extended pi-conjugation, is prepared as a highly efficient photocatalyst for degradation of methylene blue. Carbon 14-20 Sp2 transcription factor Homo sapiens 10-13 32174438-1 2020 In the current study, poly 4-hydroxyphenyl methacrylate-carbon nano-onions (PHPMA-CNOs = f-CNOs) are synthesized and reinforced with natural protein gelatin (GL) to engineer GL/f-CNOs composite hydrogels under the sonochemical method. Carbon 56-62 nitric oxide synthase 3 Homo sapiens 82-86 32174438-1 2020 In the current study, poly 4-hydroxyphenyl methacrylate-carbon nano-onions (PHPMA-CNOs = f-CNOs) are synthesized and reinforced with natural protein gelatin (GL) to engineer GL/f-CNOs composite hydrogels under the sonochemical method. Carbon 56-62 nitric oxide synthase 3 Homo sapiens 91-95 32174438-1 2020 In the current study, poly 4-hydroxyphenyl methacrylate-carbon nano-onions (PHPMA-CNOs = f-CNOs) are synthesized and reinforced with natural protein gelatin (GL) to engineer GL/f-CNOs composite hydrogels under the sonochemical method. Carbon 56-62 nitric oxide synthase 3 Homo sapiens 91-95 31889430-0 2020 Fibrinogen alphaC-regions are not directly involved in fibrin polymerization as evidenced by a "Double-Detroit" recombinant fibrinogen mutant and knobs-mimic peptides. Carbon 16-17 fibrinogen beta chain Homo sapiens 0-10 32096912-2 2020 Herein, a sp2 carbon-conjugated covalent triazine polymer (sp2 c-CTP-4), featuring a vinylene bridge and extended pi-conjugation, is prepared as a highly efficient photocatalyst for degradation of methylene blue. Carbon 14-20 Sp2 transcription factor Homo sapiens 59-62 32096912-3 2020 sp2 c-CTP-4 exhibits substantial semiconducting properties such as enhanced charge transfer and prolonged lifetime of carriers compared to its counterparts with C N or C C connections, likely due to its extended pi-delocalization with an unencumbered C C bridge. Carbon 4-6 Sp2 transcription factor Homo sapiens 0-3 32280216-0 2020 An Electrochemical Aptasensor Platform Based on Flower-Like Gold Microstructure-Modified Screen-Printed Carbon Electrode for Detection of Serpin A12 as a Type 2 Diabetes Biomarker. Carbon 104-110 serpin family A member 12 Homo sapiens 138-148 32023146-2 2020 OSBPL1 also encodes the truncated variant ORP1S that that contains only the C-terminal lipid binding domain. Carbon 76-77 oxysterol binding protein 2 Homo sapiens 0-6 31967407-6 2020 In particular two proteins, the cellular mRNA deadenylase CCR4 (carbon catabolite repressor 4)-NOT (Negative on TATA) complex subunit 2/9 (CNOT2/9) and the serine hydroxymethyltransferase that catalyzes the reversible interconversions of serine and glycine (SHMT1) were found at dramatic low levels in the thymic epithelia of more malignant subtype, thymic squamous cell carcinoma (TSCC). Carbon 64-70 CCR4-NOT transcription complex subunit 2 Homo sapiens 139-147 32244786-6 2020 Desorption study showed that diclofenac is strongly bonded, albeit with a different degree depending on the modification of the CMK-carbon. Carbon 132-138 C-X-C motif chemokine ligand 9 Homo sapiens 128-131 32357736-2 2020 A pure SP3 carbon bond in the cubic lattice structure is confirmed by Raman spectrum analysis. Carbon 11-17 Sp3 transcription factor Homo sapiens 7-10 32280216-1 2020 Purpose: In the present study, a highly sensitive and simple electrochemical (EC) aptasensor for the detection of serpin A12 as a novel biomarker of diabetes was developed on a platform where flower-like gold microstructures (FLGMs) are electrodeposited onto a disposable screen-printed carbon electrode. Carbon 287-293 serpin family A member 12 Homo sapiens 114-124 32115954-2 2020 The base-promoted reaction is operationally simple and exhibits a broad substrate scope to forge a variety of alkyl-alkyl bonds, including between sterically encumbered secondary and tertiary sp3-carbons. Carbon 196-203 Sp3 transcription factor Homo sapiens 192-195 32075911-0 2020 The C-terminal domain of feline and bovine SAMHD1 proteins has a crucial role in lentiviral restriction. Carbon 4-5 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Bos taurus 43-49 31983437-5 2020 Studies have reported that CRBN recognizes the C-terminal region of the amyloid precursor protein (APP), a protein known for its involvement in the development of Alzheimer"s disease. Carbon 27-28 amyloid beta precursor protein Homo sapiens 72-97 32210295-0 2020 Fluorescent sp3 Defect-Tailored Carbon Nanotubes Enable NIR-II Single Particle Imaging in Live Brain Slices at Ultra-Low Excitation Doses. Carbon 32-38 Sp3 transcription factor Homo sapiens 12-15 32210295-5 2020 To accomplish this, we synthesized fluorescent sp3-defect tailored (6,5) carbon nanotubes which, when excited at their first order excitonic transition (~985 nm) fluoresce brightly at ~1160 nm. Carbon 73-79 Sp3 transcription factor Homo sapiens 47-50 32024695-6 2020 We found here that C-terminally truncated Drosophila TnT (TpnT-CD70) retains binding of tropomyosin, troponin I, and troponin C, indicating a preserved core structure of TnT. Carbon 19-20 wings up A Drosophila melanogaster 101-111 31996302-7 2020 Changes in the fluorescence of AEDANS attached to C-terminal Cys of actin, as well as FRET between Trp residues in actin subdomain 1 and AEDANS, did not show differences in the conformation of the C-terminal segment of F-actin in the presence of different tropomyosins +- cofilin 1. Carbon 0-1 actin Saccharomyces cerevisiae S288C 68-73 32292750-0 2020 Effect of Vitamins C and E Co-Supplementation on Serum C-Reactive Protein Level: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Carbon 19-20 C-reactive protein Homo sapiens 55-73 32041399-0 2020 Investigation of sp2-Carbon Pattern Geometry in Boron-Doped Diamond Electrodes for the Electrochemical Quantification of Hypochlorite at High Concentrations. Carbon 21-27 Sp2 transcription factor Homo sapiens 17-20 32041399-1 2020 An electrochemical sensor that contains patterned regions of sp2-carbon in a boron-doped diamond (BDD) matrix is presented for the quantitative detection of hypochlorite (OCl-) at high concentrations in the alkaline, chemically oxidizing environment associated with bleach. Carbon 65-71 Sp2 transcription factor Homo sapiens 61-64 32041399-2 2020 As BDD itself is unresponsive to OCl- reduction within the solvent window, by using a laser micromachining process, it is possible to write robust electrochemically active regions of sp2-carbon into the electrochemically inert sp3-BDD electrode. Carbon 187-193 Sp2 transcription factor Homo sapiens 183-186 32041399-2 2020 As BDD itself is unresponsive to OCl- reduction within the solvent window, by using a laser micromachining process, it is possible to write robust electrochemically active regions of sp2-carbon into the electrochemically inert sp3-BDD electrode. Carbon 187-193 Sp3 transcription factor Homo sapiens 227-230 32125865-2 2020 In the present study, tracking of human vascular endothelial growth factor (VEGF) was achieved by chemically linking it to photoluminescent carbon dots (CDs). Carbon 140-146 vascular endothelial growth factor A Homo sapiens 40-74 32125865-2 2020 In the present study, tracking of human vascular endothelial growth factor (VEGF) was achieved by chemically linking it to photoluminescent carbon dots (CDs). Carbon 140-146 vascular endothelial growth factor A Homo sapiens 76-80 32125865-3 2020 Carbon dots were synthesized by the hydrothermal method and, subsequently, conjugated with VEGF using carbodiimide coupling. Carbon 0-6 vascular endothelial growth factor A Homo sapiens 91-95 32203557-7 2020 The oxidation process is a reflection of decreases in the number of defects related to sp2 bonds on amorphous carbons and increases in the number of defects associated with ionic impurities, which clearly indicate the interaction between biochar particles and the soil matrix. Carbon 110-117 Sp2 transcription factor Homo sapiens 87-90 31887499-1 2020 Recent studies have shown the effect of nitrate (NO3-) on carbon gas emissions from wetland soils that contradict thermodynamic predictions. Carbon 58-64 NBL1, DAN family BMP antagonist Homo sapiens 49-52 32148046-2 2020 The reaction that operates without the need for any preformed carbon nucleophile proceeds via the combination of two different bond activation processes, i.e. Ni-catalyzed imide activation via C(acyl)-N bond cleavage and (TMS)3Si radical-mediated alkyl halide activation via halogen-atom abstraction. Carbon 62-68 PYD and CARD domain containing Homo sapiens 222-225 32188449-6 2020 DAF-12 and AAK-2 separately promote a shift in the molar ratios between competing enzymes at two key branch points within the central carbon metabolic pathway diverting carbon atoms from the TCA cycle and directing them to gluconeogenesis. Carbon 134-140 Nuclear hormone receptor family member daf-12 Caenorhabditis elegans 0-6 32188449-6 2020 DAF-12 and AAK-2 separately promote a shift in the molar ratios between competing enzymes at two key branch points within the central carbon metabolic pathway diverting carbon atoms from the TCA cycle and directing them to gluconeogenesis. Carbon 169-175 Nuclear hormone receptor family member daf-12 Caenorhabditis elegans 0-6 32044549-3 2020 The aim of the present study was to determine the effects of the carbon/nitrogen (C/N) ratio and moisture content (MC) on the survival of ESBL-producing E. coli during laboratory-scale composting of chicken manure. Carbon 65-71 EsbL Escherichia coli 138-142 32187978-5 2020 Moreover, we observed that this combination greatly inhibited OSA cell motility and invasion, accompanied by the suppression of the Pi3K/Akt and MAPK signaling pathways, which are related to cell proliferation and survival, compared to individual treatments with carbon-ion beam or X-ray irradiation, or ZOL. Carbon 263-269 AKT serine/threonine kinase 1 Homo sapiens 137-140 31806304-10 2020 The biochar rate of 60 t ha-1 is recommended for carbon sequestration in terms of the more pronounced negative priming of native SOC, while the feasible combination between other biochars and soils needs further clarification. Carbon 49-55 1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic Zea mays 25-29 31855815-7 2020 We have demonstrated that the method using the carbon dots for Fe3+ ions detection was rapid, reliable, and selective with a detection limit as low as 0.720 muM and a dynamic range from 5.0 to 500.0 muM. Carbon 47-53 latexin Homo sapiens 157-160 31855815-7 2020 We have demonstrated that the method using the carbon dots for Fe3+ ions detection was rapid, reliable, and selective with a detection limit as low as 0.720 muM and a dynamic range from 5.0 to 500.0 muM. Carbon 47-53 latexin Homo sapiens 199-202 31917986-5 2020 The FTIR (Fourier transform infrared spectroscopy) and 13C CP-MAS NMR (Cross-polarization magic angle spinning carbon-13 solid state nuclear magnetic resonance spectroscopy) analysis revealed that Pb(II) binds to the carboxyl group in case of AA and to the carbonyl & amine group in case of AmAA, which leads to increase in its adsorption efficiency. Carbon 111-117 submaxillary gland androgen regulated protein 3B Homo sapiens 197-203 31917988-6 2020 We find that AIM4 has a binding site in the C-terminal amyloidogenic region (aa: 288-319), with Gly-288 & Phe-289 residues which are also important for TDP-43"s LLPS. Carbon 44-45 TAR DNA binding protein Homo sapiens 156-162 31785912-1 2020 Boron doped ordered mesoporous carbon (BMC) was prepared to improve the adsorption of Pb(II). Carbon 31-37 submaxillary gland androgen regulated protein 3B Homo sapiens 86-92 32057234-5 2020 As an example, the resultant IrP2-rGO displays better HER electrocatalytic performance and longer durability than the benchmark materials of commercial Pt/C under acidic, neutral and basic electrolytes. Carbon 155-156 iron responsive element binding protein 2 Homo sapiens 29-33 32108198-3 2020 The reaction was triggered by addition of a SCF3 radical to a carbon-carbon double bond and involved the formation of a C(sp3)-SCF3 bond, a C(sp2)-C bond, and a C(sp2)-N bond. Carbon 62-68 Sp2 transcription factor Homo sapiens 140-145 32108198-3 2020 The reaction was triggered by addition of a SCF3 radical to a carbon-carbon double bond and involved the formation of a C(sp3)-SCF3 bond, a C(sp2)-C bond, and a C(sp2)-N bond. Carbon 62-68 Sp2 transcription factor Homo sapiens 161-166 32108198-3 2020 The reaction was triggered by addition of a SCF3 radical to a carbon-carbon double bond and involved the formation of a C(sp3)-SCF3 bond, a C(sp2)-C bond, and a C(sp2)-N bond. Carbon 69-75 Sp2 transcription factor Homo sapiens 140-145 32108198-3 2020 The reaction was triggered by addition of a SCF3 radical to a carbon-carbon double bond and involved the formation of a C(sp3)-SCF3 bond, a C(sp2)-C bond, and a C(sp2)-N bond. Carbon 69-75 Sp2 transcription factor Homo sapiens 161-166 32108198-3 2020 The reaction was triggered by addition of a SCF3 radical to a carbon-carbon double bond and involved the formation of a C(sp3)-SCF3 bond, a C(sp2)-C bond, and a C(sp2)-N bond. Carbon 45-46 Sp2 transcription factor Homo sapiens 140-145 32108198-3 2020 The reaction was triggered by addition of a SCF3 radical to a carbon-carbon double bond and involved the formation of a C(sp3)-SCF3 bond, a C(sp2)-C bond, and a C(sp2)-N bond. Carbon 45-46 Sp2 transcription factor Homo sapiens 161-166 32170469-0 2020 Carbon dots-embedded epitope imprinted polymer for targeted fluorescence imaging of cervical cancer via recognition of epidermal growth factor receptor. Carbon 0-6 epidermal growth factor receptor Homo sapiens 119-151 32170469-1 2020 A carbon dots-embedded epitope imprinted polymer (C-MIP) was fabricated for targeted fluorescence imaging of cervical cancer by specifically recognizing the epidermal growth factor receptor (EGFR). Carbon 2-8 epidermal growth factor receptor Homo sapiens 157-189 32170469-1 2020 A carbon dots-embedded epitope imprinted polymer (C-MIP) was fabricated for targeted fluorescence imaging of cervical cancer by specifically recognizing the epidermal growth factor receptor (EGFR). Carbon 2-8 epidermal growth factor receptor Homo sapiens 191-195 32170469-10 2020 Graphical abstract An oriented epitope imprinted polymer embedded with carbon dots was prepared for the determination of the epitopes of epidermal growth factor receptor and targeted fluorescence imaging of cervical cancer. Carbon 71-77 epidermal growth factor receptor Homo sapiens 137-169 32218789-9 2020 IC87114 also attenuated poly I:C-induced increases in numbers of total cells, macrophages, neutrophils and lymphocytes, as well as levels of KC, IL-6 and MIP-1beta in bronchoalveolar lavage fluid. Carbon 1-2 interleukin 6 Homo sapiens 145-149 32034093-0 2020 Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products. Carbon 17-18 coagulation factor II, thrombin Homo sapiens 0-8 32034093-1 2020 Thrombin-derived C-terminal peptides (TCPs), including a major 11-kDa fragment (TCP96), are produced through cleavage by human neutrophil elastase and aggregate lipopolysaccharide (LPS) and the Gram-negative bacterium Escherichia coli. Carbon 17-18 coagulation factor II, thrombin Homo sapiens 0-8 31751971-6 2020 In addition, the content of carbon deposition was found to be higher in the matrix of Ni-P-SiC composite coating than that in the Ni-P-TiC coating. Carbon 28-34 pleckstrin and Sec7 domain containing 4 Homo sapiens 135-138 32053385-1 2020 Since a graphene sheet consists of unsaturated sp2 carbon bonds, the addition reaction for the saturating aromatic bonds can lead to a variety of non-natural two-dimensional (2D) materials. Carbon 51-57 Sp2 transcription factor Homo sapiens 47-50 32029103-1 2020 Carbon dots (CDs) were synthesized from p-aminophenol and ethylenediamine via one-step under mild condition and used as a sensitive fluorescent nanoprobe for the activity determination of N-acetyl-beta-d-glucosaminidase (NAG). Carbon 0-6 N-acetyl-alpha-glucosaminidase Homo sapiens 221-224 32218789-10 2020 Gene expression of IFNbeta, IFNlambda2 and IFN-stimulated genes (ISGs) were upregulated in response to poly I:C and a further increase in gene expression was observed following IC87114 treatment. Carbon 110-111 interferon alpha 1 Homo sapiens 19-26 32218789-10 2020 Gene expression of IFNbeta, IFNlambda2 and IFN-stimulated genes (ISGs) were upregulated in response to poly I:C and a further increase in gene expression was observed following IC87114 treatment. Carbon 110-111 interferon alpha 1 Homo sapiens 19-22 32218789-13 2020 IC87114 decreased poly I:C-induced PD-L1 expression on PBECs and secretion of IL-6 and IL-8 into culture supernatants. Carbon 1-2 interleukin 6 Homo sapiens 78-82 32218789-13 2020 IC87114 decreased poly I:C-induced PD-L1 expression on PBECs and secretion of IL-6 and IL-8 into culture supernatants. Carbon 1-2 C-X-C motif chemokine ligand 8 Homo sapiens 87-91 31794432-0 2020 Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice. Carbon 18-24 glycine decarboxylase Mus musculus 80-101 31794432-3 2020 Gldc functions in the glycine cleavage system, a mitochondrial component of folate metabolism, whose malfunction results in accumulation of glycine and diminished supply of glycine-derived 1-carbon units to the folate cycle. Carbon 191-197 glycine decarboxylase Mus musculus 0-4 31794432-6 2020 Furthermore, ventriculomegaly was rescued by genetic ablation of 5,10-methylene tetrahydrofolate reductase (Mthfr), which results in retention of 1-carbon groups in the folate cycle at the expense of transfer to the methylation cycle. Carbon 148-154 methylenetetrahydrofolate reductase Mus musculus 65-106 31794432-6 2020 Furthermore, ventriculomegaly was rescued by genetic ablation of 5,10-methylene tetrahydrofolate reductase (Mthfr), which results in retention of 1-carbon groups in the folate cycle at the expense of transfer to the methylation cycle. Carbon 148-154 methylenetetrahydrofolate reductase Mus musculus 108-113 31751628-3 2020 Like mammalian NF-kappaB p100, C-terminal truncation allows nuclear translocation of Aq-NF-kappaB and increases its transcriptional activation activity. Carbon 31-32 nuclear factor kappa B subunit 1 Homo sapiens 15-24 32201801-1 2020 Both theory and experiment show that sp2 carbon nanomaterials doped with N have great potential as high-efficiency catalysts for oxygen reduction reactions (ORR). Carbon 41-47 Sp2 transcription factor Homo sapiens 37-40 32016568-6 2020 In the sensing process, SOD and CuInZnS QDs on a glassy carbon electrode (GCE) competed with each other for hydrogen peroxide to produce superoxide during electrochemical luminescence, thus quenching the ECL signal of CuInZnS QDs. Carbon 56-62 superoxide dismutase 1 Homo sapiens 24-27 31862235-9 2020 We also provide a literature survey of more prochiral substrates, all of which have sp2 hybridized carbon and contain a prochiral plane. Carbon 99-105 Sp2 transcription factor Homo sapiens 84-87 31862235-10 2020 An example of a prochiral unnatural substrate for sphingosine kinase 2, fingolimod, has an sp3 hybridized prochiral carbon and also contains a prochiral plane. Carbon 116-122 Sp3 transcription factor Homo sapiens 91-94 31751628-2 2020 Aq-NF-kappaB is most similar to NF-kappaB p100/p105 among vertebrate proteins, with an N-terminal DNA-binding domain, a C-terminal Ankyrin (ANK) repeat domain, and a DNA binding-site profile akin to human NF-kappaB proteins. Carbon 120-121 nuclear factor kappa B subunit 1 Homo sapiens 3-12 31868611-0 2020 Fluorometric determination of amifostine and alkaline phosphatase on amphiprotic molecularly imprinted silica crosslinked with binary functional silanes and carbon dots. Carbon 157-163 alkaline phosphatase, placental Homo sapiens 45-65 31751628-3 2020 Like mammalian NF-kappaB p100, C-terminal truncation allows nuclear translocation of Aq-NF-kappaB and increases its transcriptional activation activity. Carbon 31-32 nuclear factor kappa B subunit 1 Homo sapiens 88-97 31751628-4 2020 Expression of IkappaB kinases (IKKs) induces proteasome-dependent C-terminal processing of Aq-NF-kappaB in human cells, and processing requires C-terminal serines in Aq-NF-kappaB. Carbon 66-67 nuclear factor kappa B subunit 1 Homo sapiens 94-103 31751628-5 2020 Unlike NF-kappaB p100, C-terminal sequences of Aq-NF-kappaB do not inhibit its DNA-binding activity. Carbon 23-24 nuclear factor kappa B subunit 1 Homo sapiens 50-59 31840235-4 2020 Carbon accumulation averaged 1.08 Mg ha-1 yr-1 , while species richness was effectively constant over the studied period. Carbon 0-6 Rho GTPase activating protein 45 Homo sapiens 37-47 31912675-5 2020 RESULTS: The PD-L1 expression was upregulated by C-ion beam in a dose-dependent manner in HeLa and SiHa cells through phosphorylated Chk1. Carbon 49-50 checkpoint kinase 1 Homo sapiens 133-137 31863939-7 2020 Applying granular activated carbon as a post-treatment step could successfully reduce the total DBP concentration from 295.33 mug L-1 to 82.04 mug L-1 in Leachate A, leading to a total DBP removal of 72.2% and a toxicity removal of 50%. Carbon 28-34 D-box binding PAR bZIP transcription factor Homo sapiens 96-99 31863939-7 2020 Applying granular activated carbon as a post-treatment step could successfully reduce the total DBP concentration from 295.33 mug L-1 to 82.04 mug L-1 in Leachate A, leading to a total DBP removal of 72.2% and a toxicity removal of 50%. Carbon 28-34 D-box binding PAR bZIP transcription factor Homo sapiens 185-188 31724223-4 2020 Not only did we determine that Ras signaling inhibited TGF-beta-induced KLF5 acetylation and interfered with TGF-beta function in p15 induction and Myc repression, but also TGF-beta-induced SMAD3 C-terminal region phosphorylation was necessary for TGF-beta to induce KLF5 acetylation. Carbon 196-197 transforming growth factor beta 1 Homo sapiens 55-63 31809770-6 2020 Here, we review the action of these four and multiple other N- and C-terminally truncated forms of GIP with an emphasis on molecular pharmacology, i.e. ligand binding, subsequent receptor activation and desensitization. Carbon 67-68 gastric inhibitory polypeptide Homo sapiens 99-102 31931141-0 2020 APOE alters glucose flux through central carbon pathways in astrocytes. Carbon 41-47 apolipoprotein E Homo sapiens 0-4 31809770-7 2020 Our overall conclusion is that the N-terminus is essential for receptor activation as GIP N-terminal truncation leads to decreased/lost intrinsic activity and antagonism (similar to GLP-1 and GLP-2), whereas the C-terminal extension of GIP(1-42), as compared to GLP-1, GLP-2 and glucagon (29-33 amino acids), has no apparent impact on the GIPR in vitro, but may play a role for other properties such as stability and tissue distribution. Carbon 212-213 gastric inhibitory polypeptide Homo sapiens 236-239 31496028-3 2020 A detailed analysis of the structural and compositional transformations in these processes indicates that the GF experiences considerable exfoliation and defluorination, during which sp2 -bonded carbon is partially recovered despite significant structural defects being introduced. Carbon 195-201 Sp2 transcription factor Homo sapiens 183-186 31874860-5 2020 Conversion from pyruvate to acetate is activated under hypoxic conditions, and ACS recovers carbon that would otherwise be lost from the plant as ethanol. Carbon 92-98 acetyl-CoA synthetase Arabidopsis thaliana 79-82 32075547-3 2021 For the oxidation of aromatic NOM moieties that absorb light at UV254, a lower ozone dose (1.0 g O3/m3) is sufficient, whereas to achieve a measurable reduction (about 20%) of total organic carbon, an ozone dose of 1.5 g O3/m3 is required. Carbon 190-196 immunoglobulin kappa variable 2D-38 (pseudogene) Homo sapiens 97-102 32049440-1 2020 Different from graphene with the highly stable sp2 -hybridized carbon atoms, which shows poor controllability for constructing strong interactions between graphene and guest metal, graphdiyne has a great potential to be engineered because its high-reactive acetylene linkages can effectively chelate metal atoms. Carbon 63-69 Sp2 transcription factor Homo sapiens 47-50 32121126-0 2020 Refinement of Sustainable Polybutylene Adipate Terephthalate (PBAT) with Amorphous Hydrogenated Carbon Films (a-C:H) Revealing Film Instabilities Influenced by a Thickness-Dependent Change of sp2/sp3 Ratio. Carbon 96-102 Sp2 transcription factor Homo sapiens 192-205 32108109-4 2020 This strategy conveniently engages alkyl and aryl halides in a wide range of redox transformations to construct sp3-sp3, sp3-sp2, and sp2-sp2 carbon-carbon bonds under mild conditions with high chemoselectivity. Carbon 142-148 Sp2 transcription factor Homo sapiens 134-137 32108109-4 2020 This strategy conveniently engages alkyl and aryl halides in a wide range of redox transformations to construct sp3-sp3, sp3-sp2, and sp2-sp2 carbon-carbon bonds under mild conditions with high chemoselectivity. Carbon 142-148 Sp2 transcription factor Homo sapiens 134-137 32108109-4 2020 This strategy conveniently engages alkyl and aryl halides in a wide range of redox transformations to construct sp3-sp3, sp3-sp2, and sp2-sp2 carbon-carbon bonds under mild conditions with high chemoselectivity. Carbon 149-155 Sp3 transcription factor Homo sapiens 112-115 32108109-4 2020 This strategy conveniently engages alkyl and aryl halides in a wide range of redox transformations to construct sp3-sp3, sp3-sp2, and sp2-sp2 carbon-carbon bonds under mild conditions with high chemoselectivity. Carbon 149-155 Sp2 transcription factor Homo sapiens 134-137 32108109-4 2020 This strategy conveniently engages alkyl and aryl halides in a wide range of redox transformations to construct sp3-sp3, sp3-sp2, and sp2-sp2 carbon-carbon bonds under mild conditions with high chemoselectivity. Carbon 149-155 Sp2 transcription factor Homo sapiens 134-137 32066999-2 2020 Using ethanol and ammonia as precursors, N-graphene with low relative amount of bonded oxygen and low level of saturated sp3 carbon bonds was produced. Carbon 125-131 Sp3 transcription factor Homo sapiens 121-124 32027803-6 2020 Strikingly, the mass activity and specific activity of H-PtNiCu-AAT NPs (0.977 A mg-1Pt and 1.458 mA cm-2) is 7.1 and 6.9 times higher than that of commercial Pt/C (0.138 A mg-1Pt and 0.212 mA cm-2), respectively. Carbon 61-62 serpin family A member 1 Homo sapiens 64-67 32073082-4 2020 Theoretical calculations indicate that coupling Mo2C, N and CANs into a hybrid results in producing wrinkles on carbon nanolayers, which changes the direction of sp2 hybrid orbitals to push the Gibbs free energy toward zero. Carbon 112-118 Sp2 transcription factor Homo sapiens 162-165 32120988-0 2020 Proinflammatory Effect of Carbon-Based Nanomaterials: In Vitro Study on Stimulation of Inflammasome NLRP3 via Destabilisation of Lysosomes. Carbon 26-32 NLR family pyrin domain containing 3 Homo sapiens 100-105 33828899-1 2020 Atomic resolution X-ray crystallography has shown that an intermediate (the X5P-ThDP adduct) of the catalytic cycle of transketolase (TK) displays a significant, putatively highly energetic, out-of-plane distortion in a sp 2 carbon adjacent to a lytic bond, suggested to lower the barrier of the subsequent step, and thus was postulated to embody a clear-cut demonstration of the intermediate destabilization effect. Carbon 225-231 transketolase Homo sapiens 119-132 32120988-4 2020 In this work, we compared multi-walled carbon nanotubes (MWCNT) and two different types of pristine GP in their potential to activate inflammasome NLRP3 (The nod-like receptor family pyrin domain containing 3) in vitro. Carbon 39-45 NLR family pyrin domain containing 3 Homo sapiens 147-152 31547976-9 2020 Finally, we provided evidence that the C-terminal tail of DHHC5 can be palmitoylated in response to stimulation and such modification is important for its dynamic localization and function in the plasma membrane. Carbon 39-40 zinc finger DHHC-type palmitoyltransferase 5 Homo sapiens 58-63 32166001-2 2020 SLC25A32 transports tetrahydrofolate (THF) as well as FAD into mitochondria and regulates mitochondrial one-carbon metabolism and redox balance. Carbon 108-114 solute carrier family 25 member 32 Homo sapiens 0-8 31788874-1 2020 Copper-catalyzed stereoconvergent allylation of chiral sp3-hybridized carbon nucleophiles with a racemic mixture of acyclic secondary allylic phosphates is reported. Carbon 70-76 Sp3 transcription factor Homo sapiens 55-58 31714778-4 2020 However, not all kinases un- dergo such a large configurational change: The MAPK extracellular signal-regulated protein kinases ERK1 and ERK2 achieve a 50,000 fold increase in kinase activity with only a small motion of the C-terminal region. Carbon 224-225 mitogen-activated protein kinase 3 Homo sapiens 128-132 31714778-4 2020 However, not all kinases un- dergo such a large configurational change: The MAPK extracellular signal-regulated protein kinases ERK1 and ERK2 achieve a 50,000 fold increase in kinase activity with only a small motion of the C-terminal region. Carbon 224-225 mitogen-activated protein kinase 1 Homo sapiens 137-141 31932304-6 2020 The results of these analyses indicated that Opi3 (as well as PEMT) has an N-out C-in topology and contains four transmembrane domains, with the fourth forming a re-entrant loop. Carbon 81-82 phosphatidylethanolamine N-methyltransferase Homo sapiens 62-66 31883308-0 2020 Molecular Engineering of Fully-Conjugated sp2 Carbon-Linked Polymers for High-Efficiency Photocatalytic Hydrogen Evolution. Carbon 46-52 Sp2 transcription factor Homo sapiens 42-45 32043885-1 2020 The first example of metal-free cyanomethylenation from alkyl nitriles of sp3 C-H bonds to afford quaternary carbon centers is described. Carbon 109-115 Sp3 transcription factor Homo sapiens 74-77 31945496-0 2020 Thiol antioxidants sensitize malabaricone C induced cancer cell death via reprogramming redox sensitive p53 and NF-kappaB proteins in vitro and in vivo. Carbon 42-43 tumor protein p53 Homo sapiens 104-107 32081972-5 2020 Double layer absorbers with F1/CB1(ferrite as matching and carbon black as absorbing layer with each thickness of 1 mm) structure showed the best microwave absorption performance in which more than 99% microwave energy were absorbed, with promising minimum reflection loss of -24.0 dB, along with a wider bandwidth of 4.8 GHz and yet with a reduced thickness of only 2 mm. Carbon 59-65 cannabinoid receptor 1 Homo sapiens 31-34 31945496-0 2020 Thiol antioxidants sensitize malabaricone C induced cancer cell death via reprogramming redox sensitive p53 and NF-kappaB proteins in vitro and in vivo. Carbon 42-43 nuclear factor kappa B subunit 1 Homo sapiens 112-121 32001526-4 2020 The C-terminal alpha-helix of SMARCB1, enriched in positively charged residues frequently mutated in cancers, mediates interactions with an acidic patch of nucleosome. Carbon 4-5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Homo sapiens 30-37 31923716-1 2020 Racemic tolvaptan possessing an asymmetric carbon is metabolized to three pairs of monohydroxylate enantiomers of diol form with V2 receptor antagonistic activity via CYP3A. Carbon 43-49 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 167-172 32077676-2 2020 Yin Yang 1 is composed of an N-terminal intrinsically disordered fragment and a C-terminal domain responsible for binding to DNA, composed of four zinc fingers. Carbon 80-81 YY1 transcription factor Homo sapiens 0-10 32080236-6 2020 Graphite, amorphous, and ZrC1-x carbon signatures are observed in the 13C NMR spectra of samples and are determined to vary in intensity with sintering temperature and stoichiometry. Carbon 32-38 solute carrier family 30 member 10 Homo sapiens 25-29 31972090-2 2020 Systematic microstructure investigation reveals that the carbon layers are well-distributed in the MgB2 matrix without agglomeration. Carbon 57-63 secretoglobin family 2A member 1 Homo sapiens 99-103 31972090-3 2020 The thickness of the carbon layers is less than the coherent length of MgB2, which enable them to be transparent to supercurrent. Carbon 21-27 secretoglobin family 2A member 1 Homo sapiens 71-75 31990180-1 2020 The integration of sp2/sp3-bonded carbon has aroused increasing attentions on attaining a great electron field emission (EFE) performance. Carbon 34-40 Sp3 transcription factor Homo sapiens 23-26 31990180-7 2020 This work will promote the development of high-performance cathode EFE material based on hybrid sp2/sp3-bonded carbon, and the method proposed here also provides an effective strategy to construct diamond nanostructure for various applications. Carbon 111-117 Sp3 transcription factor Homo sapiens 100-103 31972090-0 2020 Carbon Coating Layers on Boron Generated High Critical Current Density in MgB2 Superconductor. Carbon 0-6 secretoglobin family 2A member 1 Homo sapiens 74-78 31972090-1 2020 Boron particles with homogeneous carbon coating layer were employed as the precursor to fabricate MgB2 superconductors to generate artificial two-dimensional (2D) flux pinning centers. Carbon 33-39 secretoglobin family 2A member 1 Homo sapiens 98-102 32080236-7 2020 In this study a method is outlined to quantify the stoichiometry of ZrC1-x and free carbon phases, providing an improvement over the sole use and reliance of widely adopted bulk carbon combustion analysis. Carbon 178-184 solute carrier family 30 member 10 Homo sapiens 68-72 31970984-0 2020 High-affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-terminal Proline-rich Domain of SOS1. Carbon 69-70 growth factor receptor bound protein 2 Homo sapiens 55-59 31970984-3 2020 Grb2 consists of an SH2 domain flanked by N- and C-terminal SH3 domains (nSH3/cSH3). Carbon 49-50 growth factor receptor bound protein 2 Homo sapiens 0-4 31845388-3 2020 The unique sp/sp2 carbon-conjugated TA-BGY possesses an extended porous network structure with a BET surface area of approximately 300 m2 g-1 . Carbon 18-24 Sp2 transcription factor Homo sapiens 14-17 32017543-6 2020 Subsequently, the resulting remote carbon-centered radicals formed by C-C cleavage merge with the nickel catalytic cycle to create the challenging C(sp3)-C(sp2) bonds. Carbon 35-41 Sp2 transcription factor Homo sapiens 154-159 32085439-15 2020 Consequently, SUMO3, ALC1, POLE4, PCBP4, MUTYH expression correlated with the higher RBE of carbon ions. Carbon 92-98 DNA polymerase epsilon 4, accessory subunit Homo sapiens 27-32 32140162-10 2020 Temperature, MA/CA, and 1-MCP alter fruit physiology and biochemistry, resulting in compositional changes in carbon- and nitrogen-related metabolisms and compounds. Carbon 109-115 CD46 molecule Homo sapiens 26-29 32085632-2 2020 In this study, the binding mechanism of PFCAs with different carbon lengths to human serum albumin (HSA) was studied at the molecular level by means of fluorescence spectroscopy under simulated physiological conditions and molecular modeling. Carbon 61-67 albumin Homo sapiens 85-98 31672377-0 2020 The study of the interaction mechanism between bovine serum albumin and single-walled carbon nanotubes depending on their diameter and concentration in solid nanocomposites by vibrational spectroscopy. Carbon 86-92 albumin Homo sapiens 54-67 31740260-1 2020 We develop a low-background electrochemical biosensor for one-step detection of uracil DNA glycosylase (UDG) based on the host-guest interaction and iron-embedded nitrogen-rich carbon nanotube (Fe-N-C) that mimics enzyme-mediated electrocatalysis to achieve signal amplification. Carbon 177-183 uracil DNA glycosylase Homo sapiens 80-102 31740260-1 2020 We develop a low-background electrochemical biosensor for one-step detection of uracil DNA glycosylase (UDG) based on the host-guest interaction and iron-embedded nitrogen-rich carbon nanotube (Fe-N-C) that mimics enzyme-mediated electrocatalysis to achieve signal amplification. Carbon 177-183 uracil DNA glycosylase Homo sapiens 104-107 32118154-1 2020 To fully understand the chemical structure of graphene oxide and the oxidation chemistry of sp2 carbon sites, we conducted a practical experiment and density functional theory combined study on the oxidation process of graphite. Carbon 96-102 Sp2 transcription factor Homo sapiens 92-95 33464866-4 2020 In this study, carboxyl and amino groups were respectively introduced onto carbon nanotubes, a nanoreinforcement for synthetic scaffold materials, which were subsequently covalently attached to the RGD/BMP-2 osteogenic peptide. Carbon 75-81 bone morphogenetic protein 2 Mus musculus 202-207 32052190-4 2020 A glass carbon electrode (GCE) modified with Ag-g-C3N4 can immobilize a large number of amino-terminated thrombin binding aptamers (NH2-TBA) through strong Ag-N bonds. Carbon 8-14 coagulation factor II, thrombin Homo sapiens 105-113 31967806-9 2020 Carbon and nitrogen bulk isotope ratios analyzed using isotope ratio mass spectrometry (IRMS) were used to obtain some insight into the production method (organic vs. conventional) and geographic source of the milk powder samples. Carbon 0-6 Weaning weight-maternal milk Bos taurus 210-214 32049977-7 2020 A conserved seven amino acid motif EEGEVFL, which is similar to the monoleucine C-terminal to an acidic cluster motif involved in the basolateral targeting for some growth factors, has been shown to be required for matriptase translocation to the basolateral plasma membrane of polarized MDCK cells. Carbon 68-81 ST14 transmembrane serine protease matriptase Rattus norvegicus 215-225 32053949-1 2020 The interphase layer surrounding nanoparticles can reflect the tunneling effect as the main mechanism of charge transferring in polymer/carbon nanotube (CNT) nanocomposites (PCNT). Carbon 136-142 pericentrin Homo sapiens 174-178 31555812-0 2020 PhosphoSer727 triggers a multi-step inactivation of STAT3 by rapid dissociation of pY705-SH2 through C-terminal tail modulation. Carbon 101-102 signal transducer and activator of transcription 3 Homo sapiens 52-57 32050437-8 2020 Furthermore, the azoR genes had a significant negative relationship with total organic carbon, Hg, and Cr (p < 0.05). Carbon 87-93 NAD(P)H quinone dehydrogenase 1 Homo sapiens 17-21 31593929-1 2020 Graphene, sp2 hybridized allotrope of carbon with a honeycombed lattice structure has found profound applications in biomedicine owing to its unique physico-chemical properties. Carbon 38-44 Sp2 transcription factor Rattus norvegicus 10-13 31784087-0 2020 Kinesin associated protein, DmKAP, binding harnesses the C-terminal ends of the Drosophila kinesin-2 stalk heterodimer. Carbon 57-58 Kinesin associated protein 3 Drosophila melanogaster 28-33 32046086-5 2020 sp3/sp2 carbon bond ratio in the films decreased with the increase of the Cu amount in the films. Carbon 8-14 Sp3 transcription factor Homo sapiens 0-3 32046086-5 2020 sp3/sp2 carbon bond ratio in the films decreased with the increase of the Cu amount in the films. Carbon 8-14 Sp2 transcription factor Homo sapiens 4-7 31784087-0 2020 Kinesin associated protein, DmKAP, binding harnesses the C-terminal ends of the Drosophila kinesin-2 stalk heterodimer. Carbon 57-58 Kinesin associated protein 3 Drosophila melanogaster 91-100 31784087-4 2020 Here, using the Fluorescence Lifetime assay, we show that DmKAP binding selectively reduces the distance between the C-terminal ends of Drosophila kinesin-2 stalk heterodimer. Carbon 117-118 Kinesin associated protein 3 Drosophila melanogaster 58-63 31899612-8 2020 In this study, we employed dissipative particle dynamics, a coarse-grained simulation method with soft core potentials, utilizing the crystal structure information to unravel Abeta dodecamer structures with C-terminal regions. Carbon 207-208 amyloid beta precursor protein Homo sapiens 175-180 31917542-5 2020 The weak/moderate acidic sites present in the mixed metal oxide resulted in excellent catalytic properties towards the sp3-sp2 carbon-carbon coupling reactions. Carbon 127-140 Sp3 transcription factor Homo sapiens 119-122 31917542-5 2020 The weak/moderate acidic sites present in the mixed metal oxide resulted in excellent catalytic properties towards the sp3-sp2 carbon-carbon coupling reactions. Carbon 127-140 Sp2 transcription factor Homo sapiens 123-126 31784087-4 2020 Here, using the Fluorescence Lifetime assay, we show that DmKAP binding selectively reduces the distance between the C-terminal ends of Drosophila kinesin-2 stalk heterodimer. Carbon 117-118 Kinesin associated protein 3 Drosophila melanogaster 147-156 31784087-5 2020 Insertion of a missense mutation (E551K) in the Drosophila kinesin-2alpha stalk fragment, which was shown to reduce the structural dynamics of the stalk heterodimer earlier, also reduced the distances at both the N- and C-terminal ends of the stalk heterodimer independent of DmKAP. Carbon 220-221 Kinesin associated protein 3 Drosophila melanogaster 276-281 31784087-7 2020 Together, these results suggest that the KAP binding could alter the structural dynamics of kinesin-2 stalk heterodimer at the C-terminal end and stabilize the association between the stalk domains. Carbon 127-128 Kinesin associated protein 3 Drosophila melanogaster 41-44 31784087-7 2020 Together, these results suggest that the KAP binding could alter the structural dynamics of kinesin-2 stalk heterodimer at the C-terminal end and stabilize the association between the stalk domains. Carbon 127-128 Kinesin associated protein 3 Drosophila melanogaster 92-101 31927922-0 2020 Unusual electrochemical properties of low-doped boron-doped diamond electrodes containing sp2 carbon. Carbon 94-100 Sp2 transcription factor Homo sapiens 90-93 31927922-6 2020 This work indicates that, the electrochemical proper-ties of low-doped BDD containing sp2 might be due partially to the high level of surface oxygen, the large work function, the low carrier density and the existence of different types of sp2 carbon. Carbon 243-249 Sp2 transcription factor Homo sapiens 86-89 31927922-6 2020 This work indicates that, the electrochemical proper-ties of low-doped BDD containing sp2 might be due partially to the high level of surface oxygen, the large work function, the low carrier density and the existence of different types of sp2 carbon. Carbon 243-249 Sp2 transcription factor Homo sapiens 239-242 31927922-3 2020 However, we found that the poten-tial window and redox reaction in normally doped (1%) BDD and low doped (0.1%) BDD exhibited opposite tendencies depending on the extent of sp2 carbon. Carbon 177-183 Sp2 transcription factor Homo sapiens 173-176 31927922-4 2020 Moreover, we found that contrary to the usual expectations, low-doped BDD con-taining sp2 carbon hinders electron transfer, whereas in line with expectations, normally-doped BDD containing sp2 exhibits enhanced electron transfer. Carbon 90-96 Sp2 transcription factor Homo sapiens 86-89 31821485-3 2020 The current study investigates the importance of the two isoenzymes of pyruvate carboxylase (PYC1 and PYC2) and one of the key enzymes of the glyoxylate cycle (ICL1) for growth on glycerol (C3) as a sole carbon source. Carbon 204-210 pyruvate carboxylase 2 Saccharomyces cerevisiae S288C 102-106 31879997-3 2020 Here, a new strategy is demonstrated to synthesize active and stable Pt-based electrocatalysts for hydrogen evolution by confining Pt clusters in hollow mesoporous carbon spheres (Pt5 /HMCS). Carbon 164-170 MKKS centrosomal shuttling protein Homo sapiens 185-189 31730747-0 2020 Formation of secondary brown carbon in biomass burning aerosol proxies through NO3 radical reactions. Carbon 29-35 NBL1, DAN family BMP antagonist Homo sapiens 79-82 31883592-3 2020 To construct such a versatile platform, the model analyte, carcinoembryonic antigen (CEA), was captured by magnetic Fe3O4 nanoparticles bound with primary antibodies (Fe3O4-Ab1) and then recognized by the detection antibodies conjugated complex containing poly(amidoamine) (PAMAM), carbon nanotube (CNT) and carboxyl functionalized CdSe nanocrystals (NCs) (CNT-PAMAM-CdSe NCs-Ab2). Carbon 282-288 CEA cell adhesion molecule 3 Homo sapiens 59-83 31883592-3 2020 To construct such a versatile platform, the model analyte, carcinoembryonic antigen (CEA), was captured by magnetic Fe3O4 nanoparticles bound with primary antibodies (Fe3O4-Ab1) and then recognized by the detection antibodies conjugated complex containing poly(amidoamine) (PAMAM), carbon nanotube (CNT) and carboxyl functionalized CdSe nanocrystals (NCs) (CNT-PAMAM-CdSe NCs-Ab2). Carbon 282-288 CEA cell adhesion molecule 3 Homo sapiens 85-88 31685543-5 2020 HCC cell lines expressed C-terminal-truncated AR-SV; 28 primary HCC samples abundantly expressed AR-SV. Carbon 1-2 androgen receptor Homo sapiens 46-48 31988506-4 2020 Here we developed a macrophage-specific nanotherapy based on single-walled carbon nanotubes loaded with a chemical inhibitor of the antiphagocytic CD47-SIRPalpha signalling axis. Carbon 75-81 signal-regulatory protein alpha Mus musculus 152-161 31765768-4 2020 rPrx5-Grx derivatives bearing a substituted C-terminal lysine residue (rPrx5-GrxK244A), but not the active site cysteine residue (rPrx5-GrxC185A) or the sub-terminal rPrx5-GrxK230A lysine residue, exhibited significantly reduced Plg-binding. Carbon 44-45 glutaredoxin Rattus norvegicus 0-9 31924668-2 2020 INF2 is regulated by interaction between its N-terminal diaphanous inhibitory domain (DID) and its C-terminal diaphanous autoregulatory domain (DAD). Carbon 99-100 inverted formin 2 Homo sapiens 0-4 31924668-14 2020 CONCLUSIONS: INF2 is cleaved into an N-terminal DID-containing fragment and a C-terminal DAD-containing fragment. Carbon 0-1 inverted formin 2 Homo sapiens 13-17 31502903-0 2020 N6-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon black particles in rats. Carbon 158-164 AKT serine/threonine kinase 1 Rattus norvegicus 76-79 31857182-0 2020 Balanced Th1/Th2 immune response induced by a MSP1a functional motif coupled to multiwalled carbon nanotubes as anti-anaplasmosis vaccine in murine model. Carbon 92-98 negative elongation factor complex member C/D, Th1l Mus musculus 9-12 31988506-5 2020 We demonstrate that these single-walled carbon nanotubes accumulate within the atherosclerotic plaque, reactivate lesional phagocytosis and reduce the plaque burden in atheroprone apolipoprotein-E-deficient mice without compromising safety, and thereby overcome a key translational barrier for this class of drugs. Carbon 40-46 apolipoprotein E Mus musculus 180-196 31645646-7 2020 Our data show that the GRB2 adapter associates with RET51 through interactions with its C-terminal sequences, facilitating recruitment of active ARF6 and GGA3 interaction, and that depletion of GGA3 or ARF6 reduced RET51 recycling. Carbon 88-89 growth factor receptor bound protein 2 Homo sapiens 23-27 31840428-0 2020 Correlation Analysis of C-terminal telopeptide of collagen type II and Interleukin-1beta for Early Diagnosis of Knee Osteoarthritis. Carbon 0-1 interleukin 1 beta Homo sapiens 71-88 31645646-7 2020 Our data show that the GRB2 adapter associates with RET51 through interactions with its C-terminal sequences, facilitating recruitment of active ARF6 and GGA3 interaction, and that depletion of GGA3 or ARF6 reduced RET51 recycling. Carbon 88-89 golgi associated, gamma adaptin ear containing, ARF binding protein 3 Homo sapiens 194-198 31841782-6 2020 Among them, hyperelodione C showed the most potent inhibitory activities and dose-dependent PARP cleavage. Carbon 12-27 poly(ADP-ribose) polymerase 1 Homo sapiens 92-96 32385215-2 2020 The magnetic field could enhance the denitrification efficiency, especially for wastewater with low C/N ratios, and the average removal efficiencies of NO3--N increased by 6.58%. Carbon 100-101 NBL1, DAN family BMP antagonist Homo sapiens 152-155 32460279-3 2020 With the same influent NO3--N concentration of 50 mg/L and the same C/N ratio of 1.5, the NO3--N removal rate with the mixed carbon source (96.53%) was slightly lower than that with sodium acetate (98.15%), but significantly higher than that with glucose (74.69%). Carbon 125-131 NBL1, DAN family BMP antagonist Homo sapiens 23-26 32460279-3 2020 With the same influent NO3--N concentration of 50 mg/L and the same C/N ratio of 1.5, the NO3--N removal rate with the mixed carbon source (96.53%) was slightly lower than that with sodium acetate (98.15%), but significantly higher than that with glucose (74.69%). Carbon 125-131 NBL1, DAN family BMP antagonist Homo sapiens 90-93 32023808-0 2020 C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W). Carbon 0-1 solute carrier family 30 member 8 Homo sapiens 48-53 32023808-2 2020 hZnT8 consists of a transmembrane domain, with its N- and C-termini protruding into the cytoplasm. Carbon 58-59 solute carrier family 30 member 8 Homo sapiens 0-5 31880460-1 2020 Cytochrome c, an essential protein of the electron transport chain, is known to be capable of amplifying the toxicity of carbon nanomaterials via free-radical generation. Carbon 121-127 cytochrome c, somatic Homo sapiens 0-12 32001652-2 2020 Classical substitution reactions via SN1 and SN2 pathways are limited in their ability to generate carbon-carbon bonds (inadequate scope, due to side reactions such as rearrangements and eliminations) and to control stereochemistry when beginning with readily available racemic starting materials (racemic products). Carbon 99-112 solute carrier family 38 member 3 Homo sapiens 37-40 32001652-2 2020 Classical substitution reactions via SN1 and SN2 pathways are limited in their ability to generate carbon-carbon bonds (inadequate scope, due to side reactions such as rearrangements and eliminations) and to control stereochemistry when beginning with readily available racemic starting materials (racemic products). Carbon 99-112 solute carrier family 38 member 5 Homo sapiens 45-48 31616924-2 2020 Cerebrospinal fluid (CSF) APOE binds only high-density lipoproteins (HDL), while plasma APOE attaches to lipoproteins of diverse sizes with binding fine-tuned by the C-terminal loop. Carbon 0-1 apolipoprotein E Homo sapiens 26-30 31846310-7 2020 Interestingly, our comparative analysis of non-phosphorylated and phosphorylated rhodopsin structure demonstrated enhanced receptor stability upon phosphorylation at the C-terminal region that leads to the opening of the extracellular part of the transmembrane helices. Carbon 170-171 rhodopsin Homo sapiens 81-90 31913599-4 2020 Herein, we develop a graphitic carbon nitride (g-C3N4)-derived bamboo-like carbon nanotubes/carbon-wrapped Co nanoparticles (BCNT/Co) electrocatalyst by a simple high-temperature pyrolysis and acid-leaching method. Carbon 31-37 craniofacial development protein 1 Homo sapiens 125-129 31913599-4 2020 Herein, we develop a graphitic carbon nitride (g-C3N4)-derived bamboo-like carbon nanotubes/carbon-wrapped Co nanoparticles (BCNT/Co) electrocatalyst by a simple high-temperature pyrolysis and acid-leaching method. Carbon 75-81 craniofacial development protein 1 Homo sapiens 125-129 32013110-4 2020 The p42, p44, p46, p48 and p52 isoform proteins were each able to induce RNase-mediated rRNA cleavage in response to poly(I:C) when overexpressed in HEK293 cells. Carbon 124-126 interferon regulatory factor 9 Homo sapiens 19-22 32013110-4 2020 The p42, p44, p46, p48 and p52 isoform proteins were each able to induce RNase-mediated rRNA cleavage in response to poly(I:C) when overexpressed in HEK293 cells. Carbon 124-126 nuclear factor kappa B subunit 2 Homo sapiens 27-30 31616924-8 2020 CSF APOE held almost ten-fold more abundant C-terminal (Thr289, Ser290 and Ser296) glycosylation (36.8% of CSF peptide283-299 was glycosylated, 3.8% of plasma peptide283-299), with sialylated and disialylated (Neu5Acalpha2-3Galbeta1-3(Neu5Acalpha2-6)GalNAcalpha1-) core 1 structures. Carbon 0-1 apolipoprotein E Homo sapiens 4-8 32064386-0 2020 Comparison of Attachment and Antibacterial Activity of Covalent and Noncovalent Lysozyme-Functionalized Single-Walled Carbon Nanotubes. Carbon 118-124 lysozyme Homo sapiens 80-88 31924745-3 2020 The, so far resolved, disparate structural details have provided insights into linear elongation; however, molecular details like the C-terminal domain of the alpha-chain, the heparin-binding domain on the beta-chain, and other functional domains remain elusive. Carbon 134-135 Fc gamma receptor and transporter Homo sapiens 159-170 32064386-1 2020 Carbon nanotube-lysozyme (LSZ) conjugates provide an attractive combination of high strength and antimicrobial activity. Carbon 0-6 lysozyme Homo sapiens 16-24 31864632-5 2020 Under optimal conditions, the NH2-MWCNT/ZnO modified screen printed carbon electrode (SPCE) exhibits a broad linear response from 0.2 to 803.4 muM, excellent selectivity of 2.71 muAmuM-1cm-2, and a very low limit of detection (LOD) of 0.002 muM. Carbon 68-74 latexin Homo sapiens 143-146 31989332-4 2020 The average values for total biomass and total carbon measured in this study are 866.67 +- 166.10 t ha-1 and 444.68 +- 83.70 t ha-1, respectively. Carbon 47-53 Rho GTPase activating protein 45 Homo sapiens 100-104 31989332-4 2020 The average values for total biomass and total carbon measured in this study are 866.67 +- 166.10 t ha-1 and 444.68 +- 83.70 t ha-1, respectively. Carbon 47-53 Rho GTPase activating protein 45 Homo sapiens 127-131 31989332-5 2020 The average soil organic carbon recorded was 3.73 +- 2.10 t ha-1 and average litter carbon was 0.59 +- 0.20 t ha-1, respectively. Carbon 25-31 Rho GTPase activating protein 45 Homo sapiens 60-64 31864632-5 2020 Under optimal conditions, the NH2-MWCNT/ZnO modified screen printed carbon electrode (SPCE) exhibits a broad linear response from 0.2 to 803.4 muM, excellent selectivity of 2.71 muAmuM-1cm-2, and a very low limit of detection (LOD) of 0.002 muM. Carbon 68-74 latexin Homo sapiens 181-184 31830412-4 2020 HypX has a bipartite structure composed of an N-terminal module similar to N10-formyl-THF transferases and a C-terminal module homologous to enoyl-CoA hydratases/isomerases. Carbon 109-110 HPT Homo sapiens 0-4 31927483-7 2020 We further determined the structure of simian immunodeficiency virus (SIV) Nef harboring this region, demonstrating similar C-terminal alpha-helix, which may contribute to AP-1 binding for MHC-I downregulation. Carbon 124-125 nef protein Simian immunodeficiency virus 75-78 31945731-6 2020 We found that Atg32 C-terminal domain mediates dependency on Tom20, whereas the cytosolic domains of Atg32 and Gem1 facilitate MIM involvement. Carbon 20-21 translocase of outer mitochondrial membrane 20 Homo sapiens 61-66 31980627-3 2020 Kindlin-2, through its C-terminal region, binds to and stabilizes MafA, which activates insulin expression. Carbon 23-24 insulin Homo sapiens 88-95 31974343-0 2020 Regenerable and stable sp2 carbon-conjugated covalent organic frameworks for selective detection and extraction of uranium. Carbon 27-33 Sp2 transcription factor Homo sapiens 23-26 31974343-2 2020 Here we report a sp2 carbon-conjugated fluorescent covalent organic framework (COF) named TFPT-BTAN-AO with excellent chemical, thermal and radiation stability is synthesized by integrating triazine-based building blocks with amidoxime-substituted linkers. Carbon 21-27 Sp2 transcription factor Homo sapiens 17-20 31624846-0 2020 AKINbeta1, a regulatory subunit of SnRK1, regulates organic acid metabolism and acts as a global regulator of genes involved in carbon, lipid and nitrogen metabolism. Carbon 128-134 5'-AMP-activated protein kinase beta-2 subunit protein Arabidopsis thaliana 0-9 31742997-0 2020 Adoption of a Turn Conformation Drives the Binding Affinity of p53 C-Terminal Domain Peptides to 14-3-3sigma. Carbon 19-20 tumor protein p53 Homo sapiens 63-66 31968628-5 2020 The results indicated that the carbon-carbon double bond group at the C2, C3 sites and the carbonyl group at the C4 sites of flavones were essential for thrombin inhibition, whereas the methoxy and O-glycosyl groups reduced thrombin inhibition. Carbon 31-44 coagulation factor II, thrombin Homo sapiens 153-161 31968628-5 2020 The results indicated that the carbon-carbon double bond group at the C2, C3 sites and the carbonyl group at the C4 sites of flavones were essential for thrombin inhibition, whereas the methoxy and O-glycosyl groups reduced thrombin inhibition. Carbon 31-44 coagulation factor II, thrombin Homo sapiens 224-232 31872753-9 2020 We observed that the electrochemical decarboxylative methoxylation of oxazolidine and thiazolidine derivatives with the appropriate N-protecting group occurred in a stereospecific manner even though the reaction proceeded through an sp2 planar carbon center. Carbon 244-250 Sp2 transcription factor Homo sapiens 233-236 31742997-2 2020 A phosphorylated motif within the C-terminal domain (CTD) of p53 is key for binding to the amphipathic groove of 14-3-3. Carbon 34-35 tumor protein p53 Homo sapiens 61-64 31561243-1 2020 Nanoimprinting behaviors of copper substrate and double-walled carbon nanotube (DWCNT) with interwall sp3 bonds are investigated by using molecular dynamics (MD) simulations. Carbon 63-69 Sp3 transcription factor Homo sapiens 102-105 31963914-0 2020 Sustainable Biomass Glucose-Derived Porous Carbon Spheres with High Nitrogen Doping: As a Promising Adsorbent for CO2/CH4/N2 Adsorptive Separation. Carbon 43-49 chimerin 2 Homo sapiens 118-124 31953488-4 2020 Truncated p53 mutants modulated droplet formation, suggesting the importance of multivalent electrostatic interactions among the N-terminal and C-terminal domains. Carbon 144-145 tumor protein p53 Homo sapiens 10-13 32010139-7 2019 Analysis of the binding of chimeric MBP-HA peptides demonstrated that the observed difference between MBP153-161, MBP90-98, and HA peptide epitopes is caused by the lack of anchor residues in the C-terminal part of the MBP peptides resulting in a moderate occupation of P6/7 and P9 pockets of HLA-DRB1*01:01 by MBP153-161 and MBP90-98 peptides in contrast to HA308-316 peptide. Carbon 196-197 major histocompatibility complex, class II, DR beta 1 Homo sapiens 293-301 31953488-5 2020 Second, FRET efficiency measurements for the dimer mutants of p53 revealed that distances between the core domains and between the C-terminal domains were modulated in an opposite manner within the droplets. Carbon 131-132 tumor protein p53 Homo sapiens 62-65 31851480-0 2020 Cu(II) Regulated on-site Assembly of Highly Chemiluminescent Multifunctionalized Carbon Nanotubes for Inorganic Pyrophosphatase Activity Determination. Carbon 81-87 inorganic pyrophosphatase 1 Homo sapiens 102-127 31801692-5 2020 These findings prompted us to re-investigate oxidation of unsaturated fatty acids and fatty alcohols with C9-C16 carbon chain length by CYP4B1. Carbon 113-119 cytochrome P450 family 4 subfamily B member 1 Homo sapiens 136-142 31801692-8 2020 Docking results for the corresponding CYP4B1-substrate complexes revealed that fatty acids can adopt U-shaped bonding conformations, such that carbon atoms in both arms may approach the heme-iron. Carbon 143-149 cytochrome P450 family 4 subfamily B member 1 Homo sapiens 38-44 31911482-4 2020 Two of PHF10 isoforms lacking C-terminal PHD domains contain a cluster of phosphorylated serine residues, designated as X-cluster. Carbon 30-31 PHD finger protein 10 Homo sapiens 7-12 31851480-1 2020 A novel signal-on chemiluminescence (CL) assay for pyrophosphatase (PPase) activity determination was innovatively developed based on Cu(II) regulated on-site assembly of highly chemiluminescent Cu(II), N-(aminobutyl)-N-(ethylisoluminol) (ABEI), gold nanodots and chitosan multifunctionalized carbon nanotubes (Cu(II)/ABEI-Au/cs-CNTs). Carbon 293-299 inorganic pyrophosphatase 1 Homo sapiens 51-66 31851480-1 2020 A novel signal-on chemiluminescence (CL) assay for pyrophosphatase (PPase) activity determination was innovatively developed based on Cu(II) regulated on-site assembly of highly chemiluminescent Cu(II), N-(aminobutyl)-N-(ethylisoluminol) (ABEI), gold nanodots and chitosan multifunctionalized carbon nanotubes (Cu(II)/ABEI-Au/cs-CNTs). Carbon 293-299 inorganic pyrophosphatase 1 Homo sapiens 68-73 31594586-6 2020 The thrombin aptamer2-functionalized magnetic carbon nanotubes (MCNTs-Apt2) were used as a matrix, and Cu-TCPP(Co) MOFs/Au-ssDNA was adsorbed on the MCNTs by the complementary pairing of the partial bases between ssDNA and Apt2. Carbon 46-52 coagulation factor II, thrombin Homo sapiens 4-12 31938922-4 2020 CNTs have an excellent ability to penetrate cell membranes, and the sp2 hybridization of all carbons enables their functionalization with almost every biomolecule or compound, allowing them to target cells and deliver drugs under the appropriate environmental stimuli. Carbon 93-100 Sp2 transcription factor Homo sapiens 68-71 31889000-3 2020 Here we report that Ndel1"s C-terminal coiled-coil region (CT-CC) binds to giant neuron-specific insertion regions present in both AnkG and AnkB with 2:1 stoichiometry. Carbon 28-29 ankyrin 3 Homo sapiens 131-135 31850427-6 2020 The L10-PtZn nanoparticles embedded in a hollow carbon nanocage obtained from one-step annealing of Pt2+-exchanged ZIF-8 showed better electrocatalytic activity and durability toward methanol oxidation under acidic electrolyte conditions than those obtained from commercial Pt/C catalysts. Carbon 48-54 immunoglobulin kappa variable 3-7 (non-functional) Homo sapiens 4-7 31776190-6 2020 This analysis revealed that SIN3 and SAM-S regulate overlapping pathways, many of which involve one-carbon and central carbon metabolisms. Carbon 100-106 Sin3A Drosophila melanogaster 28-32 31776190-6 2020 This analysis revealed that SIN3 and SAM-S regulate overlapping pathways, many of which involve one-carbon and central carbon metabolisms. Carbon 119-125 Sin3A Drosophila melanogaster 28-32 31829619-0 2020 Immobilization and Function of nIR-Fluorescent Carbon Nanotube Sensors on Paper Substrates for Fluidic Manipulation. Carbon 47-53 NOC2 like nucleolar associated transcriptional repressor Homo sapiens 31-34 31950087-1 2020 Carbon-based frameworks composed of sp3 bonding represent a class of extremely lightweight strong materials, but only diamond and a handful of other compounds exist despite numerous predictions. Carbon 0-6 Sp3 transcription factor Homo sapiens 36-39 31829619-3 2020 Here, we have developed a technique for immobilizing nIR-fluorescent single-walled carbon nanotube (SWCNT) sensors on seven different types of paper substrates including nitrocellulose, nylon, poly(vinylidene fluoride), and cellulose. Carbon 83-89 NOC2 like nucleolar associated transcriptional repressor Homo sapiens 53-56 31756441-5 2020 The N4-amino group of Gem is mono-amidated with di-acids containing different carbon chain lengths, which could recognize intestinal MCT1 and are bio-activated at physiological pH independent of the hydrolysis enzymes. Carbon 78-84 solute carrier family 16 member 1 Homo sapiens 133-137 31735212-4 2020 We present here the development of an electrochemical immunosensor based on nanostructured screen-printed carbon electrodes for the quantification of unfolded p53 in plasma samples. Carbon 106-112 tumor protein p53 Homo sapiens 159-162 31578296-0 2020 Conserved CxnC motifs in Kaposi"s sarcoma-associated herpesvirus ORF66 are required for viral late gene expression and are essential for its interaction with ORF34. Carbon 0-1 ORF66 Human gammaherpesvirus 8 65-70 31578296-5 2020 We show that ORF66 is incorporated into the vTA complex primarily through its interaction with ORF34, which is dependent upon a set of four conserved cysteine-rich motifs in the C-terminal domain of ORF66. Carbon 178-179 ORF66 Human gammaherpesvirus 8 13-18 31578296-5 2020 We show that ORF66 is incorporated into the vTA complex primarily through its interaction with ORF34, which is dependent upon a set of four conserved cysteine-rich motifs in the C-terminal domain of ORF66. Carbon 178-179 ORF66 Human gammaherpesvirus 8 199-204 31578296-11 2020 Here, we demonstrate that ORF66 is an essential component of this complex in KSHV and that its inclusion in the complex depends upon its C-terminal domain, which contains highly conserved cysteine-rich motifs reminiscent of zinc finger motifs. Carbon 137-138 ORF66 Human gammaherpesvirus 8 26-31 31947948-5 2020 The diamond micro-crystals with a thick oxidized amorphous sp2-carbon coating were grown at a heating power of 900 W and a hydrogen flow rate of 1500 sccm. Carbon 63-69 Sp2 transcription factor Homo sapiens 59-62 31947948-7 2020 Defective octahedral diamond crystals of 30 mum in size with a thin sp2-carbon surface layer were synthesized on a Mo substrate heated at 1273 K for 1.5 h. When the synthesis duration was doubled, and the substrate temperature was decreased to 1073 K, the denser film with rhombic-dodecahedron diamond crystals was grown. Carbon 72-78 Sp2 transcription factor Homo sapiens 68-71 31947948-8 2020 In this case, the thinnest hydrogenated sp2-carbon coating was detected on the surface of the diamond crystals. Carbon 44-50 Sp2 transcription factor Homo sapiens 40-43 31591766-1 2020 The generation of arylzinc reagents (ArZnX) by direct insertion of zinc into the C-X bond of ArX electrophiles has typically been restricted to iodides and bromides. Carbon 81-82 aristaless related homeobox Homo sapiens 93-96 31825030-5 2020 This makes C18 the smallest all-carbon electron acceptor reported so far. Carbon 32-38 Bardet-Biedl syndrome 9 Homo sapiens 11-14 31839203-4 2020 Here, we report on three individuals who have de novo MN1 variants that lead to a protein lacking the carboxyl (C) terminus and who presented with severe developmental delay, craniofacial abnormalities with specific facial features, and structural abnormalities in the brain. Carbon 112-113 MN1 proto-oncogene, transcriptional regulator Homo sapiens 54-57 31839203-5 2020 An in vitro study revealed that the deletion of the C-terminal region led to increased protein stability, an inhibitory effect on cell proliferation, and enhanced MN1 aggregation in nuclei compared to what occurred in the wild type, suggesting that a gain-of-function mechanism is involved in this disease. Carbon 52-53 MN1 proto-oncogene, transcriptional regulator Homo sapiens 163-166 31839203-6 2020 Considering that C-terminal deletion increases the fraction of intrinsically disordered regions of MN1, it is possible that altered phase separation could be involved in the mechanism underlying the disease. Carbon 0-1 MN1 proto-oncogene, transcriptional regulator Homo sapiens 99-102 31839203-8 2020 On the basis of our findings, we propose the model that C-terminal deletion interferes with MN1"s interaction molecules related to the ubiquitin-mediated proteasome pathway, including RING1, and increases the amount of the mutant protein; this increase leads to the dysregulation of MN1 target genes by inhibiting rapid MN1 protein turnover. Carbon 56-57 MN1 proto-oncogene, transcriptional regulator Homo sapiens 92-95 31839203-8 2020 On the basis of our findings, we propose the model that C-terminal deletion interferes with MN1"s interaction molecules related to the ubiquitin-mediated proteasome pathway, including RING1, and increases the amount of the mutant protein; this increase leads to the dysregulation of MN1 target genes by inhibiting rapid MN1 protein turnover. Carbon 56-57 MN1 proto-oncogene, transcriptional regulator Homo sapiens 283-286 31839203-8 2020 On the basis of our findings, we propose the model that C-terminal deletion interferes with MN1"s interaction molecules related to the ubiquitin-mediated proteasome pathway, including RING1, and increases the amount of the mutant protein; this increase leads to the dysregulation of MN1 target genes by inhibiting rapid MN1 protein turnover. Carbon 56-57 MN1 proto-oncogene, transcriptional regulator Homo sapiens 283-286 31707064-0 2020 Formation of a bovine serum albumin diligand complex with rutin and single-walled carbon nanotubes for the reduction of cytotoxicity. Carbon 82-88 albumin Homo sapiens 22-35 32116227-0 2020 [Electroanalytical and electrocatalytical characteristics of cytochrome P450 3A4 using electrodes modified with nanocomposite carbon nanomaterials]. Carbon 126-132 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 61-80 32116227-2 2020 The role and the influence of graphite working electrode modification with carbon nanotubes on electroanalytical characteristics of cytochrome P450 3A4 have been demonstrated. Carbon 75-81 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 132-151 32116227-3 2020 The conditions for the immobilization of cytochrome P450 3A4 on the obtained screen-printed graphite electrodes modified with carbon multi-walled nanotubes have been optimized. Carbon 126-132 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 41-60 31799972-2 2020 Exposure to LED light (>420 nm) led to the splitting of the dodecahexaene conjugation into two hexatriene subunits, connected through a stereogenic carbon atom. Carbon 148-154 small integral membrane protein 10 like 2A Homo sapiens 12-15 31799972-2 2020 Exposure to LED light (>420 nm) led to the splitting of the dodecahexaene conjugation into two hexatriene subunits, connected through a stereogenic carbon atom. Carbon 148-154 small integral membrane protein 10 like 2A Homo sapiens 32-35 33268711-2 2020 Recently, carborane derivatives, which are carbon-containing boron clusters have attracted attention as new AR ligands. Carbon 43-49 androgen receptor Homo sapiens 108-110 31834374-0 2020 MN1 C-terminal truncation syndrome is a novel neurodevelopmental and craniofacial disorder with partial rhombencephalosynapsis. Carbon 4-5 MN1 proto-oncogene, transcriptional regulator Homo sapiens 0-3 31834374-10 2020 We propose that the condition described here, MN1 C-terminal truncation (MCTT) syndrome, is not due to MN1 haploinsufficiency but rather is the result of dominantly acting C-terminally truncated MN1 protein. Carbon 50-51 MN1 proto-oncogene, transcriptional regulator Homo sapiens 46-49 32552653-1 2020 Myoferlin (MYOF), as a member of the ferlin family, is a type II transmembrane protein with a single transmembrane domain at the carbon terminus. Carbon 129-135 myoferlin Homo sapiens 0-9 31655058-6 2020 RC level estimated by calculated or measured LDL-C was termed as RCe1 or RCe2. Carbon 48-50 Ras converting CAAX endopeptidase 1 Homo sapiens 65-69 33268656-3 2020 Extensive computational studies revealed that the driving force of the facile hydration of 9 is probably release of the ring strain of 9, which arises in part from the bent sp2-hybridized C3a carbon. Carbon 192-198 Sp2 transcription factor Homo sapiens 173-176 32552653-1 2020 Myoferlin (MYOF), as a member of the ferlin family, is a type II transmembrane protein with a single transmembrane domain at the carbon terminus. Carbon 129-135 myoferlin Homo sapiens 11-15 31914597-3 2020 Most of the disease-causing mutations are located in the extended cytoplasmic C-terminus of Slack channels and result in increased Slack current. Carbon 78-79 potassium sodium-activated channel subfamily T member 1 Homo sapiens 92-97 31650666-7 2020 These findings indicate that Gat1 may play an important role in the dual-regulation of the nitrogen and carbon metabolisms in PMA biosynthesis. Carbon 104-110 solute carrier family 6 member 1 Homo sapiens 29-33 31914597-3 2020 Most of the disease-causing mutations are located in the extended cytoplasmic C-terminus of Slack channels and result in increased Slack current. Carbon 78-79 potassium sodium-activated channel subfamily T member 1 Homo sapiens 131-136 31914597-4 2020 Previous experiments have shown that the C-terminus of Slack channels binds a number of cytoplasmic signaling proteins. Carbon 41-42 potassium sodium-activated channel subfamily T member 1 Homo sapiens 55-60 31678645-8 2020 Current mutational pressure directions are different for AAV types, while all of them demonstrate high rates of T to C transitions in the second long ORF. Carbon 0-1 adeno-associated virus integration site 1 Homo sapiens 57-60 31726189-0 2020 Enhanced antibody response to ovalbumin coupled to poly-dispersed acid functionalized single walled carbon nanotubes. Carbon 100-106 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 30-39 31726189-5 2020 Ovalbumin was chemically coupled to AF-SWCNTs that yielded a coupled product that had 0.08% of all carbon atoms in AF-SWCNTs occupied by ovalbumin. Carbon 99-105 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 0-9 31742890-10 2020 In addition, inhibition of AMPK by employing compound C (an AMPK inhibitor) or AMPK1alpha siRNA significantly suppressed SIRT3 expression, suggesting that AMPK was an up-stream protein of SIRT3 in liver fibrosis. Carbon 54-55 sirtuin 3 Homo sapiens 121-126 30758268-1 2020 BACKGROUND: Some micronutrients like folate, vitamin B12, B6, and B2 are the source of coenzymes, which participate in one-carbon metabolism. Carbon 123-129 gastrin releasing peptide receptor Homo sapiens 58-68 32020905-4 2020 In the present study, we examined the effect of acid functionalized single-walled carbon nanotubes (AF-SWCNTs) on the function and expression of two tight junction proteins (ZO-1 and occludin) in the Madin-Darby canine kidney (MDCK) cell line. Carbon 82-88 tight junction protein 1 Canis lupus familiaris 174-191 31742890-10 2020 In addition, inhibition of AMPK by employing compound C (an AMPK inhibitor) or AMPK1alpha siRNA significantly suppressed SIRT3 expression, suggesting that AMPK was an up-stream protein of SIRT3 in liver fibrosis. Carbon 54-55 sirtuin 3 Homo sapiens 188-193 31791492-5 2020 Moreover, 1 mug/mL to 10 mug/mL carbon particle treatments disrupted the keratinocyte differentiation, and up-regulated inflammation- and psoriasis-related genes, such as IL-1beta, IL-6, CXCL1, CXCL2, CXCL3, CCL20, CXCL8, and S100A7 and S100A9, respectively. Carbon 32-38 interleukin 6 Homo sapiens 181-185 31672254-0 2020 Modeling mass transfer for adsorptive removal of Pb(II) onto phosphate modified ordered mesoporous carbon (OMC). Carbon 99-105 submaxillary gland androgen regulated protein 3B Homo sapiens 49-55 31672254-1 2020 Phosphate modified ordered mesoporous carbon (MOMC-NP) has been synthesized and proven to be an effective adsorbent for Pb(II) removal from aqueous solutions. Carbon 38-44 submaxillary gland androgen regulated protein 3B Homo sapiens 120-126 31791492-5 2020 Moreover, 1 mug/mL to 10 mug/mL carbon particle treatments disrupted the keratinocyte differentiation, and up-regulated inflammation- and psoriasis-related genes, such as IL-1beta, IL-6, CXCL1, CXCL2, CXCL3, CCL20, CXCL8, and S100A7 and S100A9, respectively. Carbon 32-38 C-X-C motif chemokine ligand 3 Homo sapiens 201-206 31791492-5 2020 Moreover, 1 mug/mL to 10 mug/mL carbon particle treatments disrupted the keratinocyte differentiation, and up-regulated inflammation- and psoriasis-related genes, such as IL-1beta, IL-6, CXCL1, CXCL2, CXCL3, CCL20, CXCL8, and S100A7 and S100A9, respectively. Carbon 32-38 C-X-C motif chemokine ligand 8 Homo sapiens 215-220 31791492-5 2020 Moreover, 1 mug/mL to 10 mug/mL carbon particle treatments disrupted the keratinocyte differentiation, and up-regulated inflammation- and psoriasis-related genes, such as IL-1beta, IL-6, CXCL1, CXCL2, CXCL3, CCL20, CXCL8, and S100A7 and S100A9, respectively. Carbon 32-38 S100 calcium binding protein A7 Homo sapiens 226-232 31871320-6 2020 As a result, FoxO1 and PGC-1alpha cooperatively upregulate Pck1 expression, therefore directing the carbon flow along the gluconeogenic pathway to glycogen and the pentose phosphate pathway. Carbon 100-106 forkhead box O1 Homo sapiens 13-18 31940105-5 2020 According to this, the carbon dots could be developed to detect mercury (II) and glutathione specifically, and the detection limit of mercury (II) is as low as 0.41 muM. Carbon 23-29 latexin Homo sapiens 165-168 31563141-2 2020 The aurora kinases A (AURKA), B (AURKB), and C (AURKC) are potential therapeutic targets in proliferating cells. Carbon 45-46 aurora kinase C Rattus norvegicus 48-53 31759040-8 2020 Moreover, C-terminal end of the Gasdermin D molecule is also cleaved by the caspase-1. Carbon 10-11 caspase 1 Homo sapiens 76-85 32016894-7 2020 Two major regions of interaction were identified: at the C-terminal tail of rhodopsin (D330-S343) and where the "finger loop" (G69-T79) of arrestin directly inserts into rhodopsin active core. Carbon 57-58 rhodopsin Homo sapiens 76-85 32016894-7 2020 Two major regions of interaction were identified: at the C-terminal tail of rhodopsin (D330-S343) and where the "finger loop" (G69-T79) of arrestin directly inserts into rhodopsin active core. Carbon 57-58 rhodopsin Homo sapiens 170-179 31931996-1 2020 In this chapter, we report a simple and facile method to armor enzymes with carbon nanotubes (CNTs) which are exfoliated, and debundled using bovine serum albumin (BSA). Carbon 76-82 albumin Homo sapiens 149-162 31642038-4 2020 Following insertion of scFv gene into a pET32a-lic vector and expression in Escherichia coli and purification, the purified scFv, was conjugated with carbon dots (C dots) and used for the detection of CD45RA +cells while CD45RA-cells served as negative control. Carbon 150-156 immunglobulin heavy chain variable region Homo sapiens 23-27 31642038-4 2020 Following insertion of scFv gene into a pET32a-lic vector and expression in Escherichia coli and purification, the purified scFv, was conjugated with carbon dots (C dots) and used for the detection of CD45RA +cells while CD45RA-cells served as negative control. Carbon 150-156 immunglobulin heavy chain variable region Homo sapiens 124-128 31290896-3 2020 From the recent mechanistic investigations, we reason that there is a shared initiating mechanism wherein a characteristic SAM methylene radical is proposed to abstract a hydrogen atom from an sp3 carbon or add onto an sp2 carbon center although variations occur thereafter from reaction to reaction, as well as providing a brief insight into some future prospects. Carbon 197-203 Sp3 transcription factor Homo sapiens 193-196 31290896-3 2020 From the recent mechanistic investigations, we reason that there is a shared initiating mechanism wherein a characteristic SAM methylene radical is proposed to abstract a hydrogen atom from an sp3 carbon or add onto an sp2 carbon center although variations occur thereafter from reaction to reaction, as well as providing a brief insight into some future prospects. Carbon 197-203 Sp2 transcription factor Homo sapiens 219-222 31871320-6 2020 As a result, FoxO1 and PGC-1alpha cooperatively upregulate Pck1 expression, therefore directing the carbon flow along the gluconeogenic pathway to glycogen and the pentose phosphate pathway. Carbon 100-106 PPARG coactivator 1 alpha Homo sapiens 23-33 31290896-3 2020 From the recent mechanistic investigations, we reason that there is a shared initiating mechanism wherein a characteristic SAM methylene radical is proposed to abstract a hydrogen atom from an sp3 carbon or add onto an sp2 carbon center although variations occur thereafter from reaction to reaction, as well as providing a brief insight into some future prospects. Carbon 223-229 Sp3 transcription factor Homo sapiens 193-196 31290896-3 2020 From the recent mechanistic investigations, we reason that there is a shared initiating mechanism wherein a characteristic SAM methylene radical is proposed to abstract a hydrogen atom from an sp3 carbon or add onto an sp2 carbon center although variations occur thereafter from reaction to reaction, as well as providing a brief insight into some future prospects. Carbon 223-229 Sp2 transcription factor Homo sapiens 219-222 31514903-0 2020 Magnetic carbon nanotube modified with polymeric deep eutectic solvent for the solid phase extraction of bovine serum albumin. Carbon 9-15 albumin Homo sapiens 112-125 31514903-1 2020 This article described the fabrication of novel magnetic carbon nanotube modified with polymeric deep eutectic solvent (M-CNT@PDES) and its application as extractant for the magnetic solid phase extraction (MSPE) of bovine serum albumin (BSA). Carbon 57-63 albumin Homo sapiens 223-236 31820955-1 2019 With the help of a judicious association between DTE units, an ytterbium ion and a ruthenium carbon-rich complex, we describe (i) the efficient (on/off) switching of pure NIR luminescence with a photochromic unit absorbing in the UV range, and (ii) the associa-tion of electrochemical and photochemical control of this NIR emission in a single system with non-destructive readout. Carbon 83-99 NOC2 like nucleolar associated transcriptional repressor Homo sapiens 171-174 33148863-4 2020 The tracer less commonly used in PET/CT could be carbon-labeled methionine (11C-MET). Carbon 49-55 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 78-83 32021158-6 2019 Results: The results show silver-doped ordered mesoporous carbons to positively condition cell viability, with a cell viability percentage >70% even for 10 wt% Ag, to modulate the expression of inflammatory cytokines and of genes involved in tissue repair (KRT6a, VEGFA, IVN) and remodeling (MMP9, TIMP3) in different cell systems. Carbon 58-65 vascular endothelial growth factor A Homo sapiens 264-269 31741382-0 2019 Quantum-Mechanical/Molecular-Mechanical Studies of CYP11A1-Catalyzed Biosynthesis of Pregnenolone from Cholesterol Reveal a C-C Bond Cleavage Reaction That Occurs by a Compound I-Mediated Electron Transfer. Carbon 59-60 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 51-58 31424204-4 2019 This study reports on the seminal discovery of a thiamin-dependent transketolase responsible for the formation of 2-acetamido-5,6-dihydroxy-6-oxoheptanoic acid, which accounts for the two-carbon extension needed to complete the carbon framework of the azabicycle moiety. Carbon 188-194 transketolase Homo sapiens 67-80 31424204-4 2019 This study reports on the seminal discovery of a thiamin-dependent transketolase responsible for the formation of 2-acetamido-5,6-dihydroxy-6-oxoheptanoic acid, which accounts for the two-carbon extension needed to complete the carbon framework of the azabicycle moiety. Carbon 228-234 transketolase Homo sapiens 67-80 31513829-11 2019 However, when MS animals were exposed to Poly (I:C), a more robust activation of Tlr3, Il6 and Nfkb1 gene transcription was observed in these mice compared with control animals. Carbon 49-50 interleukin 6 Mus musculus 87-90 31513829-11 2019 However, when MS animals were exposed to Poly (I:C), a more robust activation of Tlr3, Il6 and Nfkb1 gene transcription was observed in these mice compared with control animals. Carbon 49-50 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 95-100 31782436-0 2019 Green-emitting carbon dot loaded silica nanoparticles coated with DNA-cross-linked hydrogels for sensitive carcinoembryonic antigen detection and effective targeted cancer therapy. Carbon 15-21 CEA cell adhesion molecule 3 Homo sapiens 107-131 31782436-1 2019 Herein, we have designed bifunctional composite nanospheres for carcinoembryonic antigen (CEA) sensing and targeted drug delivery, based on carbon dot loaded silica nanoparticles coated with DNA-cross-linked hydrogels. Carbon 140-146 CEA cell adhesion molecule 3 Homo sapiens 64-88 31782436-1 2019 Herein, we have designed bifunctional composite nanospheres for carcinoembryonic antigen (CEA) sensing and targeted drug delivery, based on carbon dot loaded silica nanoparticles coated with DNA-cross-linked hydrogels. Carbon 140-146 CEA cell adhesion molecule 3 Homo sapiens 90-93 32002304-1 2020 Mutations of the gene coding for calreticulin (CALR) that cause the loss of the C-terminal KDEL motif abolish its retention in the endoplasmic reticulum and cause CALR to be secreted from cells. Carbon 47-48 calreticulin Homo sapiens 33-45 32002304-1 2020 Mutations of the gene coding for calreticulin (CALR) that cause the loss of the C-terminal KDEL motif abolish its retention in the endoplasmic reticulum and cause CALR to be secreted from cells. Carbon 47-48 calreticulin Homo sapiens 163-167 32002304-2 2020 Specific CALR mutants bearing a novel C-terminus can precipitate the manifestation of myeloproliferative diseases via the autocrine activation of the thrombopoietin receptor. Carbon 9-10 MPL proto-oncogene, thrombopoietin receptor Homo sapiens 150-173 32002304-3 2020 We recently employed the retention using selective hooks (RUSH) technology to monitor CALR trafficking and demonstrated the secretion of C-terminally truncated variants of CALR in vitro and in vivo. Carbon 86-87 calreticulin Homo sapiens 172-176 31820955-1 2019 With the help of a judicious association between DTE units, an ytterbium ion and a ruthenium carbon-rich complex, we describe (i) the efficient (on/off) switching of pure NIR luminescence with a photochromic unit absorbing in the UV range, and (ii) the associa-tion of electrochemical and photochemical control of this NIR emission in a single system with non-destructive readout. Carbon 83-99 NOC2 like nucleolar associated transcriptional repressor Homo sapiens 319-322 31769975-0 2019 Molecular interaction between distal C-terminal domain of the CB1 cannabinoid receptor and Cannabinoid Receptor Interacting Proteins (CRIP1a/CRIP1b). Carbon 37-38 cannabinoid receptor 1 Homo sapiens 62-86 31878192-2 2019 In humans, a POLR2J gene family has been identified that potentially encodes several hRPB11 proteins differing mainly in their short C-terminal regions. Carbon 133-134 RNA polymerase II subunit J Homo sapiens 13-19 31878192-2 2019 In humans, a POLR2J gene family has been identified that potentially encodes several hRPB11 proteins differing mainly in their short C-terminal regions. Carbon 133-134 RNA polymerase II subunit J Homo sapiens 85-91 31878192-6 2019 We demonstrated that the hRPB11balpha interacts with leucine b-Zip domain located on the C-terminal part of ATF4. Carbon 89-90 RNA polymerase II subunit J Homo sapiens 25-31 31769975-5 2019 The three-dimensional model of the distal C-terminal domain of the CB1R was docked with both CRIP1a as well as CRIP1b to study the crucial interactions between CB1R and CRIP1a/b. Carbon 42-43 cannabinoid receptor 1 Homo sapiens 160-164 31769975-1 2019 We have investigated the structure of the distal C-terminal domain of the of the CB1 cannabinoid receptor (CB1R) to study its interactions with CRIP1a and CRIP1b using computational techniques. Carbon 49-50 cannabinoid receptor 1 Homo sapiens 81-105 31769975-1 2019 We have investigated the structure of the distal C-terminal domain of the of the CB1 cannabinoid receptor (CB1R) to study its interactions with CRIP1a and CRIP1b using computational techniques. Carbon 49-50 cannabinoid receptor 1 Homo sapiens 107-111 31769975-2 2019 The amino acid sequence from distal C-terminal domain of CB1R (G417-L472) was found to be unique, as it does not share sequence similarity with other protein structures, so the structure was predicted using ab initio modeling. Carbon 36-37 cannabinoid receptor 1 Homo sapiens 57-61 31769975-3 2019 The computed model of distal C-terminal region of CB1R has a helical region between positions 441 to 455. Carbon 29-30 cannabinoid receptor 1 Homo sapiens 50-54 31769975-5 2019 The three-dimensional model of the distal C-terminal domain of the CB1R was docked with both CRIP1a as well as CRIP1b to study the crucial interactions between CB1R and CRIP1a/b. Carbon 42-43 cannabinoid receptor 1 Homo sapiens 67-71 33479614-6 2020 This study establishes that CYP2D6-expressing live yeast cells can be a powerful tool for the enzymatic C-N, C-C bond cleavage of amino-acids. Carbon 104-105 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 28-34 33479614-6 2020 This study establishes that CYP2D6-expressing live yeast cells can be a powerful tool for the enzymatic C-N, C-C bond cleavage of amino-acids. Carbon 104-105 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 28-34 31857576-7 2019 Our epigenetic findings provide a potential molecular link to reported aberrant 1-carbon metabolism in ESAM and support consideration of methyl-group supplementation in ESAM. Carbon 80-88 endothelial cell adhesion molecule Homo sapiens 103-107 31861855-4 2019 Graphene is a two-dimensional carbon nano-material with sp2 hybrid orbital, which has a large surface area and excellent conductivity and electron transfer ability. Carbon 30-36 Sp2 transcription factor Homo sapiens 56-59 31655647-3 2019 By using BCCPEimBr ionic liquid as the functional monomer, CEA as the template, a molecularly imprinted hydrogel film was prepared on a hollow gold nanoballs/MoSe2 nanosheets modified glassy carbon electrode surface. Carbon 191-197 CEA cell adhesion molecule 3 Homo sapiens 59-62 31857576-2 2019 Reduced concentrations and methyl-flux of methionine in 1-carbon metabolism have been reported in acute, but not recovered, ESAM, suggesting downstream DNA methylation changes could be relevant to differences in SAM pathogenesis. Carbon 56-64 endothelial cell adhesion molecule Homo sapiens 124-128 31909325-7 2019 The enhanced fluorescence upon the addition of cerium ions is due to the intramolecular charge transfer and photoinduced electron transfer processes in the sp2- and sp3-hybridized carbon networks. Carbon 180-186 Sp2 transcription factor Homo sapiens 156-159 31850845-1 2019 APOBEC3G (A3G), an enzyme expressed in primates with the potential to inhibit human immunodeficiency virus type 1 (HIV-1) infectivity, is a single-stranded DNA (ssDNA) deoxycytidine deaminase with two domains, a catalytically active, weakly ssDNA binding C-terminal domain (CTD) and a catalytically inactive, strongly ssDNA binding N-terminal domain (NTD). Carbon 5-6 apolipoprotein B mRNA editing enzyme catalytic subunit 3G Homo sapiens 10-13 31921850-12 2019 We speculate that the phosphatase Glc7/PP1, known to regulate both the cell cycle and carbon metabolism, may play an important role because its regulatory subunits are phospho-regulated in our data. Carbon 86-92 neuropeptide Y receptor Y4 Homo sapiens 34-42 31589798-1 2019 Non-heme iron halogenases are synthetically valuable biocatalysts that are capable of halogenating unactivated sp3 -hybridized carbon centers with high stereo- and regioselectivity. Carbon 127-133 Sp3 transcription factor Homo sapiens 111-114 31627810-0 2019 Nitrogen-doped carbon dots-V2O5 nanobelts sensing platform for sensitive detection of ascorbic acid and alkaline phosphatase activity. Carbon 15-21 alkaline phosphatase, placental Homo sapiens 104-124 31909325-7 2019 The enhanced fluorescence upon the addition of cerium ions is due to the intramolecular charge transfer and photoinduced electron transfer processes in the sp2- and sp3-hybridized carbon networks. Carbon 180-186 Sp3 transcription factor Homo sapiens 165-168 31722405-2 2019 Trl1 consists of three catalytic modules: an N-terminal ligase (LIG) domain; a central polynucleotide kinase (KIN) domain; and a C-terminal cyclic phosphodiesterase (CPD) domain. Carbon 129-130 tRNA-Leu (anticodon AAG) 2-3 Homo sapiens 0-4 31614141-8 2019 Compound C (an AMPK inhibitor) and LY294002 (a PI3K inhibitor) markedly reversed the alleviating effect of 10-HDA on the expression of tight junction proteins, indicating that 10-HDA inhibited LPS-induced BBB dysfunction by triggering the activation of the AMPK/PI3K/AKT pathway. Carbon 0-1 AKT serine/threonine kinase 1 Homo sapiens 267-270 31844082-0 2019 The C-terminal domain of EFA6A interacts directly with F-actin and assembles F-actin bundles. Carbon 4-5 pleckstrin and Sec7 domain containing Homo sapiens 25-30 31844082-3 2019 We previously showed that the C-terminus of EFA6 (EFA6-Ct) is the main domain which contributes to actin reorganization. Carbon 30-31 pleckstrin and Sec7 domain containing Homo sapiens 44-48 31844082-3 2019 We previously showed that the C-terminus of EFA6 (EFA6-Ct) is the main domain which contributes to actin reorganization. Carbon 30-31 pleckstrin and Sec7 domain containing Homo sapiens 50-57 31690630-7 2019 Results from negative stain EM experiments suggest that BAX undergoes secondary and tertiary structural rearrangements and incorporates into the fibers, and that its membrane-associating C-terminal helix is important for the fibrillation process. Carbon 187-188 BCL2 associated X, apoptosis regulator Homo sapiens 56-59 31615841-9 2019 Of note, siRNAs that silenced MAVS and interferon regulatory factor 1 (IRF1) expression reduced OCT3/4 levels after stimulation with poly(I:C); however, an NF-kappaB inhibitor and siRNA-mediated knockdown of proto-oncogene c-Jun did not significantly reduce the mRNA levels. Carbon 140-142 interferon regulatory factor 1 Homo sapiens 39-69 31615841-9 2019 Of note, siRNAs that silenced MAVS and interferon regulatory factor 1 (IRF1) expression reduced OCT3/4 levels after stimulation with poly(I:C); however, an NF-kappaB inhibitor and siRNA-mediated knockdown of proto-oncogene c-Jun did not significantly reduce the mRNA levels. Carbon 140-142 interferon regulatory factor 1 Homo sapiens 71-75 31830125-9 2019 This blockade is independent of the deaminase activity and requires the C-terminal region of mA3. Carbon 72-73 cholinergic receptor, nicotinic, alpha polypeptide 3 Mus musculus 93-96 31890962-8 2019 Variants of MARV GP2 containing the N- and C-terminal halves ("MGP2-FNL" and "MGP2-CMT", respectively) have similar properties. Carbon 43-44 glycoprotein 2 Homo sapiens 17-20 31809527-4 2019 Snf5 and other subunits of SWI/SNF complex were required to activate genes of carbon utilization and other carbohydrates related process specifically under hypoxia. Carbon 78-84 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mus musculus 0-4 31822614-5 2019 To this end, we analyzed the role of a conserved valine-proline (VP) motif in the C-terminal domain of CRY2 (CCT2), which resembles the core COP1-WD40-binding sequences present in the substrates of COP1. Carbon 82-83 cryptochrome 2 Arabidopsis thaliana 103-107 31593347-0 2019 Water-Induced Growth of High-Oriented Mesoporous Graphitic Carbon Nanospring for Fast K-ion Adsorption/Intercalation Storage. Carbon 49-65 Fas activated serine/threonine kinase Homo sapiens 81-87 31593347-1 2019 Here, high-oriented mesoporous graphitic carbon nanospring (OGCS) with graphitic layers that are perpendicular to the axis is prepared by hydrothermal treatment of epoxy resin at 500 C and followed by annealing at 1400 C. It is demonstrated that the water plays an important role in not only forming graphitic carbon nanospring with high [002] orientation and a large amount of active edge-plane sites, but also contributing to the generation of mesoporous structure, which both facilitate fast K-ion adsorption and diffusion. Carbon 31-47 Fas activated serine/threonine kinase Homo sapiens 490-496 33417794-3 2019 Carbon-based materials have been reported to be beneficial to soft tissue sealing, which can be regulated through the hybridization type of carbon atoms (sp2 or sp3), but its internal mechanism is still not clear. Carbon 0-6 Sp2 transcription factor Homo sapiens 154-157 33417794-3 2019 Carbon-based materials have been reported to be beneficial to soft tissue sealing, which can be regulated through the hybridization type of carbon atoms (sp2 or sp3), but its internal mechanism is still not clear. Carbon 0-6 Sp3 transcription factor Homo sapiens 161-164 33417794-3 2019 Carbon-based materials have been reported to be beneficial to soft tissue sealing, which can be regulated through the hybridization type of carbon atoms (sp2 or sp3), but its internal mechanism is still not clear. Carbon 140-146 Sp2 transcription factor Homo sapiens 154-157 33417794-3 2019 Carbon-based materials have been reported to be beneficial to soft tissue sealing, which can be regulated through the hybridization type of carbon atoms (sp2 or sp3), but its internal mechanism is still not clear. Carbon 140-146 Sp3 transcription factor Homo sapiens 161-164 33417794-4 2019 In this work, graphene oxide with both sp2- and sp3-hybridized carbons was electrophoretic deposited on titanium and reduced to regulate the hybridization type of carbon atoms to investigate its effect and possible mechanism on human gingival fibroblasts (HGFs). Carbon 63-70 Sp3 transcription factor Homo sapiens 48-51 33417794-4 2019 In this work, graphene oxide with both sp2- and sp3-hybridized carbons was electrophoretic deposited on titanium and reduced to regulate the hybridization type of carbon atoms to investigate its effect and possible mechanism on human gingival fibroblasts (HGFs). Carbon 63-69 Sp3 transcription factor Homo sapiens 48-51 31822105-1 2019 The recent synthesis of a C18 monocyclic ring constitutes a major breakthrough as a new all-carbon disclosed form. Carbon 92-98 Bardet-Biedl syndrome 9 Homo sapiens 26-29 31817360-4 2019 As GLUL activity is linked to the tricarboxylic acid (TCA) cycle via reversed glutaminolysis, we probed carbon flux through both glycolysis and TCA pathways by means of 13C5 glutamine, 13C5 glutamate, and 13C6 glucose tracing. Carbon 104-110 glutamate-ammonia ligase Homo sapiens 3-7 31817918-5 2019 Further experiments demonstrated that rubioncolin C induced apoptotic and autophagic cell death and inhibited the Akt/mTOR/P70S6K signaling pathway in HCT116 and HepG2 cells. Carbon 38-51 AKT serine/threonine kinase 1 Homo sapiens 114-117 31817918-5 2019 Further experiments demonstrated that rubioncolin C induced apoptotic and autophagic cell death and inhibited the Akt/mTOR/P70S6K signaling pathway in HCT116 and HepG2 cells. Carbon 38-51 mechanistic target of rapamycin kinase Homo sapiens 118-122 31817918-6 2019 Moreover, we observed that rubioncolin C inhibited the TNF-alpha- and LPS-induced NF-kappaB activation upstream of the p65 protein, which contributed to rubioncolin C-induced cell death. Carbon 27-40 tumor necrosis factor Homo sapiens 55-64 31817918-6 2019 Moreover, we observed that rubioncolin C inhibited the TNF-alpha- and LPS-induced NF-kappaB activation upstream of the p65 protein, which contributed to rubioncolin C-induced cell death. Carbon 153-166 tumor necrosis factor Homo sapiens 55-64 31809527-5 2019 snf5 mutant exhibited an altered metabolome reflecting that SWI/SNF plays an essential role in maintaining metabolic homeostasis and carbon flux in C. albicans under hypoxia. Carbon 133-139 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mus musculus 0-4 31809527-9 2019 Among candidates of signaling pathways in which Snf5 might operate, phenotypic analysis revealed that mutants of Ras1-cAMP-PKA pathway, as well as mutants of Yak1 and Yck2 kinases exhibited a similar carbon flexibility phenotype as did snf5 under hypoxia. Carbon 200-206 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mus musculus 48-52 31594641-2 2019 Cyclin-dependent kinase 9 (CDK9), a serine-threonine kinase, is widely implicated in the control of basal gene expression by phosphorylating Serine 2 (Ser2) of the heptad repeat in the RNA Polymerase II (RNA Pol II) C-terminal domain (CTD). Carbon 0-1 cyclin dependent kinase 9 Homo sapiens 27-31 31867286-4 2019 Gene ontology and pathway analysis of DEGs revealed that CcpA exerts an influence predominantly involved in carbon catabolite metabolism and some amino acid catabolite pathways, which has been linked to expression of virulence genes in many pathogens and coordinately regulate the disease progression in vivo studies. Carbon 108-114 catabolite control protein A Streptococcus sanguinis SK36 57-61 31594641-2 2019 Cyclin-dependent kinase 9 (CDK9), a serine-threonine kinase, is widely implicated in the control of basal gene expression by phosphorylating Serine 2 (Ser2) of the heptad repeat in the RNA Polymerase II (RNA Pol II) C-terminal domain (CTD). Carbon 0-1 polymerase (RNA) II (DNA directed) polypeptide F Mus musculus 204-214 31794565-4 2019 In studies to identify regions of MARKs that confer catalytic activity towards variant sites, we found that the C-terminal kinase associated-1 (KA1) domain in MARK1-3 mediates binding to microtubule-associated proteins CLASP1/2; but this interaction is dispensable for zetaXKXGSXXNPsi phosphorylation. Carbon 112-113 microtubule affinity regulating kinase 1 Homo sapiens 159-164 31816912-7 2019 AC1, with the highest specific surface area, possesses the best drug-loading capacity, reaching 679.18 mg/g, but the lowest drug release rate of 32.31% in 96 h. PDA-AC3 has the lowest specific surface area, showing limited drug-loading ability, 82.94 mg/g, but 100% drug release within 72 h. This study suggests that activated carbon has potent applications in agricultural pest control as an inexpensive, effective, controllable, and safe pesticide carrier. Carbon 327-333 adenylate cyclase 1 Homo sapiens 0-3 31295699-0 2019 Influence of a polymer membrane on the electrochemical determination of insulin in nanomodified screen printed carbon electrodes. Carbon 111-117 insulin Homo sapiens 72-79 31725272-7 2019 Also, the Co(II)-TMU-63//activated carbon (AC) asymmetric supercapacitor acted in a broad potential window of 1.7 V (0-1.7 V), exhibiting a high performance with 4.42 kW kg-1 power density (PD) and 24.13 Whkg-1 energy density (ED). Carbon 35-41 mitochondrially encoded cytochrome c oxidase II Homo sapiens 10-23 31867514-5 2019 Density functional theory simulations showed that 4-methylanisole presents a stronger pi-pi interaction and attraction forces with sp2 carbon nanosheets in Fe@C composites than 4-anisaldehyde. Carbon 135-141 sex-specific storage-protein 2 Bombyx mori 131-134 34057492-1 2019 A rapid, simple, selective and highly sensitive simultaneous determination of Cu(II) and Pb(II) via newly fashioned 5,11,17,23-tetra-tert-butyl-25,27-dihydrazinamidecarbonylmethoxy-26,28-dihydroxycalix[4]arene-grafted multi-walled carbon nanotubes-modified carbon paste electrode (CNT-Calix/CPE) by differential pulse anodic stripping voltammetry (DPASV) has been introduced. Carbon 165-171 submaxillary gland androgen regulated protein 3B Homo sapiens 89-95 31400567-0 2019 An impedimetric molecularly-imprinted biosensor for Interleukin-1beta determination, prepared by in-situ electropolymerization on carbon screen-printed electrodes. Carbon 130-136 interleukin 1 beta Homo sapiens 52-69 31400567-1 2019 This work reports the first electrochemical molecularly imprinted polymer (MIP) sensor for Interleukin-1beta (IL-1beta) detection, based on modified commercial screen-printed carbon electrode (SPCE) was successfully demonstrated. Carbon 175-181 interleukin 1 beta Homo sapiens 91-108 31400567-1 2019 This work reports the first electrochemical molecularly imprinted polymer (MIP) sensor for Interleukin-1beta (IL-1beta) detection, based on modified commercial screen-printed carbon electrode (SPCE) was successfully demonstrated. Carbon 175-181 interleukin 1 beta Homo sapiens 110-118 31577968-3 2019 HS-terminated hairpin-DNA aptamer of IFN-gamma was conjugated with AuNPs to prepare aptamer-AuNPs-PAMAM/MoS2 onto glassy carbon electrode (GCE), by using bovine serum albumin as the cross-linker and stabilizer. Carbon 121-127 interferon gamma Homo sapiens 37-46 31693217-6 2019 Interestingly, adiponectin treatment also activated AMPK signalling pathway by increasing the phosphorylation of Thr172 in the AMPK alpha subunit; 10muM of compound C, a potent AMPK inhibitor, blocked the protective effects of adiponectin against HG/HL-induced insulin resistance. Carbon 165-166 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 52-56 31693217-6 2019 Interestingly, adiponectin treatment also activated AMPK signalling pathway by increasing the phosphorylation of Thr172 in the AMPK alpha subunit; 10muM of compound C, a potent AMPK inhibitor, blocked the protective effects of adiponectin against HG/HL-induced insulin resistance. Carbon 165-166 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 127-131 31693217-6 2019 Interestingly, adiponectin treatment also activated AMPK signalling pathway by increasing the phosphorylation of Thr172 in the AMPK alpha subunit; 10muM of compound C, a potent AMPK inhibitor, blocked the protective effects of adiponectin against HG/HL-induced insulin resistance. Carbon 165-166 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 127-131 31693217-6 2019 Interestingly, adiponectin treatment also activated AMPK signalling pathway by increasing the phosphorylation of Thr172 in the AMPK alpha subunit; 10muM of compound C, a potent AMPK inhibitor, blocked the protective effects of adiponectin against HG/HL-induced insulin resistance. Carbon 165-166 insulin Homo sapiens 261-268 28712268-1 2019 BACKGROUND: The 1,2-decanediol (S-Mal) is an organic compound belonging to the 1,2- alkanediol family, with two hydroxyl groups located on the first and second carbon of the alkane chain, probably responsible for the enhanced anti-bacterial efficacy. Carbon 160-166 mal, T cell differentiation protein Homo sapiens 34-37 31542671-2 2019 Previous studies in vitro have shown that a variety of sorbent materials, including carbon, can sorb PCBs; however, PCB sorbents that can be added to food or drinking water to decrease toxin bioavailability in humans and animals have not been reported. Carbon 84-90 pyruvate carboxylase Homo sapiens 101-104 31683196-5 2019 The interacting domains between TRIM59 and nsp11 were further determined to be the N-terminal RING domain in TRIM59 and the C-terminal NendoU domain in nsp11, respectively. Carbon 124-125 tripartite motif containing 59 Homo sapiens 32-38 31586237-5 2019 Here within, we study the spatial organization of a large DFNB1 locus encompassing the gap junction protein beta 2 (GJB2) gene, the most frequently mutated gene in this inherited hearing loss phenotype, with the chromosome conformation capture carbon copy technology (5C). Carbon 244-250 gap junction protein beta 2 Homo sapiens 58-63 31586237-5 2019 Here within, we study the spatial organization of a large DFNB1 locus encompassing the gap junction protein beta 2 (GJB2) gene, the most frequently mutated gene in this inherited hearing loss phenotype, with the chromosome conformation capture carbon copy technology (5C). Carbon 244-250 gap junction protein beta 2 Homo sapiens 87-114 31586237-5 2019 Here within, we study the spatial organization of a large DFNB1 locus encompassing the gap junction protein beta 2 (GJB2) gene, the most frequently mutated gene in this inherited hearing loss phenotype, with the chromosome conformation capture carbon copy technology (5C). Carbon 244-250 gap junction protein beta 2 Homo sapiens 116-120 31525435-0 2019 One-carbon metabolism supplementation improves outcome after stroke in aged male MTHFR-deficient mice. Carbon 4-10 methylenetetrahydrofolate reductase Mus musculus 81-86 31525435-3 2019 Deficiencies in one-carbon metabolism, including in methyltetrahydrofolate reductase (MTHFR), have been linked to increased risk of stroke. Carbon 20-26 methylenetetrahydrofolate reductase Mus musculus 52-84 31525435-3 2019 Deficiencies in one-carbon metabolism, including in methyltetrahydrofolate reductase (MTHFR), have been linked to increased risk of stroke. Carbon 20-26 methylenetetrahydrofolate reductase Mus musculus 86-91 31832048-5 2019 Our results indicate that the full length of PP2CA is needed to interact with the GORK C-terminal region. Carbon 48-49 gated outwardly-rectifying K+ channel Arabidopsis thaliana 82-86 31154625-11 2019 Poly I:C stimulation increased mRNA expression of retinoic-acid-inducible protein I (RIG-I), melanoma-differentiation-associated gene 5 (MDA5), IFN-stimulated gene factor 3 (ISG3) complex, and IFN-stimulated genes (IRF7, ISG15, IFIT1, OAS1); nicotine attenuated mRNA expression only in WT cells. Carbon 7-8 interferon regulatory factor 7 Homo sapiens 215-219 31154625-19 2019 In the IRF7-mutant cells, nicotine"s suppressive effects on poly I:C-stimulated immune responses were restrained. Carbon 67-68 interferon regulatory factor 7 Homo sapiens 7-11 32198324-0 2019 Bio-modified carbon paste electrode for the detection of Pb(II) ions in wastewater. Carbon 13-19 submaxillary gland androgen regulated protein 3B Homo sapiens 57-63 31657122-3 2019 In this work, earth-abundant iron pyrite (FeS2 ) nanocrystals grown on carbon fiber paper (FeS2 /CFP) are found to be an electrochemical and photoactive catalyst for nitrogen reduction reaction under ambient temperature and pressure. Carbon 71-77 complement factor properdin Homo sapiens 97-100 32198324-4 2019 In this work, bio-modified carbon paste electrodes were constructed with live cells and thermally dried biomass (extracted protein) from Pseudomonas aeruginosa cells and employed for the detection of Pb(II) ions from wastewater. Carbon 27-33 submaxillary gland androgen regulated protein 3B Homo sapiens 200-206 31780554-3 2019 However, the quantum performance of carbon nanostructures has remained stunted by an inability to alter the sp2-carbon lattice with atomic precision. Carbon 112-118 Sp2 transcription factor Homo sapiens 108-111 31759698-3 2019 Here, we examine the molecular, structural, and genome-wide regulatory consequences of recurrent, single-residue mutations in the putative coiled-coil C-terminal domain (CTD) of the SMARCB1 (BAF47) subunit, which cause the intellectual disability disorder Coffin-Siris syndrome (CSS), and are recurrently found in cancers. Carbon 151-152 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Homo sapiens 182-189 31674615-5 2019 The specific capacitance vs. time-of-reduction of TRFG followed the v-shaped trend, which could be the result of the decreasing content of sp3 carbons and increasing content of structural defects. Carbon 143-150 Sp3 transcription factor Homo sapiens 139-142 31849641-2 2019 Bioactivity-guided fractionation using expression of PTGS2 (COX-2) mRNA as a readout resulted in the isolation of two C13 megastigmane glycosides, gusanlungionoside C (1) and citroside A (3), and the phenylalcohol glycoside phenylmethyl-2-O-(6-O-rhamnosyl)-ss-D-galactopyranoside (2). Carbon 147-166 mitochondrially encoded cytochrome c oxidase II Homo sapiens 60-65 31807680-3 2019 Here, we show that by chemically engineering the well depth of sp3 quantum defects through a series of alkyl functional groups covalently attached to semiconducting carbon nanotube hosts, trions can be efficiently generated and localized at the trapping chemical defects. Carbon 165-171 Sp3 transcription factor Homo sapiens 63-66 31759698-3 2019 Here, we examine the molecular, structural, and genome-wide regulatory consequences of recurrent, single-residue mutations in the putative coiled-coil C-terminal domain (CTD) of the SMARCB1 (BAF47) subunit, which cause the intellectual disability disorder Coffin-Siris syndrome (CSS), and are recurrently found in cancers. Carbon 151-152 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Homo sapiens 191-196 31735942-3 2019 In this work, hierarchically structured Ni(OH)2/NiS/CC nanosheet arrays, with the vertical growth of secondary nanosheets on their surface, are directly fabricated on a carbon cloth via an NH4F-induced method. Carbon 169-175 solute carrier family 5 member 5 Homo sapiens 48-51 31763971-0 2021 Carbon-Carbon Bond Cleavage Catalyzed by Human Cytochrome P450 Enzymes: a-Ketol as the Key Intermediate Metabolite in Sequential Metabolism of Olanexidine. Carbon 0-13 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 47-62 31661244-0 2019 Ultrafast Exciton Trapping at sp3 Quantum Defects in Carbon Nanotubes. Carbon 53-59 Sp3 transcription factor Homo sapiens 30-33 31763971-7 2021 Among 19 cytochrome P450 enzymes tested, CYP2D6, CYP3A4 and CYP3A5 were identified to catalyze carbon-carbon bond cleavage. Carbon 95-108 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 9-24 31763971-7 2021 Among 19 cytochrome P450 enzymes tested, CYP2D6, CYP3A4 and CYP3A5 were identified to catalyze carbon-carbon bond cleavage. Carbon 95-108 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 41-47 31763971-7 2021 Among 19 cytochrome P450 enzymes tested, CYP2D6, CYP3A4 and CYP3A5 were identified to catalyze carbon-carbon bond cleavage. Carbon 95-108 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 49-55 31763971-7 2021 Among 19 cytochrome P450 enzymes tested, CYP2D6, CYP3A4 and CYP3A5 were identified to catalyze carbon-carbon bond cleavage. Carbon 95-108 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 60-66 31763971-9 2021 Its mechanism is proposed that a nucleophilic addition of iron-peroxo species, generated by CYP2D6 and CYP3A4/5, to the carbonyl group caused the carbon-carbon bond cleavage between the adjacent hydroxyl and ketone groups. Carbon 146-159 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 92-98 31763971-9 2021 Its mechanism is proposed that a nucleophilic addition of iron-peroxo species, generated by CYP2D6 and CYP3A4/5, to the carbonyl group caused the carbon-carbon bond cleavage between the adjacent hydroxyl and ketone groups. Carbon 146-159 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 103-109 31758050-4 2019 First, the redox activities of different p53 redox products were qualitatively investigated on carbon-based electrodes. Carbon 95-101 tumor protein p53 Homo sapiens 41-44 31636139-9 2019 NTDs in Pax3 mutants were not associated with abnormal abundance of specific folates and were not prevented by formate, a one-carbon donor to folate metabolism. Carbon 126-132 paired box 3 Mus musculus 8-12 31642313-10 2019 The new jozibrevines A-C (1a-c) exhibited pronounced antiplasmodial activities in the submicromolar range, with 1a being the most potent compound (IC50, 0.012 muM). Carbon 8-24 latexin Homo sapiens 159-162 31604820-5 2019 Moreover, the level of an alternative larger C-terminal fragment (CTF) increased in the APP-S675E cells, whereas the CTF form that was most abundant in cells expressing APPwt or APP-S675A decreased in the APP-S675E cells. Carbon 45-46 amyloid beta precursor protein Homo sapiens 88-93 31648516-5 2019 Beyond mesostructuring, we identify the template-replica interface as a potentially versatile, but generally unexploited handle for tailoring the sp2 hybridized carbon content in the porous replicas under mild carbonization conditions and without specific chemical activation or catalytic graphitization. Carbon 161-167 Sp2 transcription factor Homo sapiens 146-149 31771091-13 2019 Thus using the well-characterized model human lung cancer model cell line (BEAS-2B), poly I:C RNA, LL37 peptide, or LL37-poly I:C complexes were loaded onto ZnO NP and delivered to BEAS-2B lung cells, and the effect on the main cancer regulating cytokine, IL-6 determined by ELISA. Carbon 128-129 cathelicidin antimicrobial peptide Homo sapiens 116-120 31766322-1 2019 Paraphaeosphaeride C is a demethoxy derivative of phaeosphaeride A and exhibits STAT3 inhibitory activity. Carbon 0-20 signal transducer and activator of transcription 3 Homo sapiens 80-85 31177000-4 2019 The carbon nanomaterial is highly dispersible in aqueous solution and can be employed as an effective optical probe for label-free detection of Fe3+ (0.87 muM) via a switched off change. Carbon 4-10 latexin Homo sapiens 155-158 31756921-3 2019 Four major classes of enzymes that attenuate TCR signaling include E3 ubiquitin kinases such as the Casitas B-lineage lymphoma proteins (Cbl-b and c-Cbl), and Itchy (Itch), inhibitory tyrosine phosphatases, such as Src homology region 2 domain-containing phosphatases (SHP-1 and SHP-2), inhibitory protein kinases, such as C-terminal Src kinase (Csk), and inhibitory lipid kinases such as Src homology 2 (SH2) domain-containing inositol polyphosphate 5-phosphatase (SHIP) and Diacylglycerol kinases (DGKs). Carbon 46-47 itchy E3 ubiquitin protein ligase Homo sapiens 159-164 31756921-3 2019 Four major classes of enzymes that attenuate TCR signaling include E3 ubiquitin kinases such as the Casitas B-lineage lymphoma proteins (Cbl-b and c-Cbl), and Itchy (Itch), inhibitory tyrosine phosphatases, such as Src homology region 2 domain-containing phosphatases (SHP-1 and SHP-2), inhibitory protein kinases, such as C-terminal Src kinase (Csk), and inhibitory lipid kinases such as Src homology 2 (SH2) domain-containing inositol polyphosphate 5-phosphatase (SHIP) and Diacylglycerol kinases (DGKs). Carbon 46-47 itchy E3 ubiquitin protein ligase Homo sapiens 159-163 31682407-0 2019 Correction to Mutual Effects of Pb(II) and Humic Acid Adsorption on Multiwalled Carbon Nanotubes/Polyacrylamide Composites from Aqueous Solutions. Carbon 80-86 submaxillary gland androgen regulated protein 3B Homo sapiens 32-38 31518072-2 2019 The mitochondrial 10-formyl-tetrahydrofolate synthetase MTHFD1L catalyzes production of formate, thus generating one-carbon units for cytoplasmic processes. Carbon 117-123 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like Mus musculus 56-63 31616886-2 2019 Herein, from first-principles calculations, we show that a synergistic effect of sp2 and sp3 hybridized C atoms can substantially enhance the Li-storage performance in carbon-based anodes, using bct-C40 as an example, which is constructed with interconnected graphene layers (sp2 hybridized C atoms) and the connecting points are composed of sp3-C atoms. Carbon 168-174 Sp2 transcription factor Homo sapiens 81-84 31616886-2 2019 Herein, from first-principles calculations, we show that a synergistic effect of sp2 and sp3 hybridized C atoms can substantially enhance the Li-storage performance in carbon-based anodes, using bct-C40 as an example, which is constructed with interconnected graphene layers (sp2 hybridized C atoms) and the connecting points are composed of sp3-C atoms. Carbon 168-174 Sp3 transcription factor Homo sapiens 89-92 31616886-2 2019 Herein, from first-principles calculations, we show that a synergistic effect of sp2 and sp3 hybridized C atoms can substantially enhance the Li-storage performance in carbon-based anodes, using bct-C40 as an example, which is constructed with interconnected graphene layers (sp2 hybridized C atoms) and the connecting points are composed of sp3-C atoms. Carbon 168-174 Sp2 transcription factor Homo sapiens 276-279 31616886-2 2019 Herein, from first-principles calculations, we show that a synergistic effect of sp2 and sp3 hybridized C atoms can substantially enhance the Li-storage performance in carbon-based anodes, using bct-C40 as an example, which is constructed with interconnected graphene layers (sp2 hybridized C atoms) and the connecting points are composed of sp3-C atoms. Carbon 168-174 Sp3 transcription factor Homo sapiens 342-345 31616886-7 2019 Our study provides new insights into the functionality of sp2- and sp3-C atoms in carbon-based anode materials and is helpful for the designing of new carbon-based anodes. Carbon 82-88 Sp2 transcription factor Homo sapiens 58-61 31616886-7 2019 Our study provides new insights into the functionality of sp2- and sp3-C atoms in carbon-based anode materials and is helpful for the designing of new carbon-based anodes. Carbon 82-88 Sp3 transcription factor Homo sapiens 67-70 31616886-7 2019 Our study provides new insights into the functionality of sp2- and sp3-C atoms in carbon-based anode materials and is helpful for the designing of new carbon-based anodes. Carbon 151-157 Sp2 transcription factor Homo sapiens 58-61 31616886-7 2019 Our study provides new insights into the functionality of sp2- and sp3-C atoms in carbon-based anode materials and is helpful for the designing of new carbon-based anodes. Carbon 151-157 Sp3 transcription factor Homo sapiens 67-70 31713740-2 2019 Carbon-encapsulated iron nanoparticles were functionalized with bovine serum albumin, coupled to monoclonal antibodies, and then used as magnetic labels. Carbon 0-6 albumin Homo sapiens 71-84 31507020-0 2019 A Highly Warped Heptagon-Containing sp2 Carbon Scaffold via Vinylnaphthyl pi-Extension. Carbon 40-46 Sp2 transcription factor Homo sapiens 36-39 31507020-1 2019 A new strategy is demonstrated for the synthesis of warped, negatively curved, all-sp2-carbon pi-scaffolds. Carbon 87-93 Sp2 transcription factor Homo sapiens 83-86 31609570-5 2019 Dehydrogenation of the thin-film and subsequent transformation of cleaved C-H bonds to non planar sp2 carbon rings were inferred from EELS and XPS results. Carbon 102-108 Sp2 transcription factor Homo sapiens 98-101 31748248-4 2019 Deletion of the C-terminal cysteine-rich domain (c-CRD), where the nuclear export signal resides, increased nuclear enrichment of Yap1 under basal conditions and altered resistance to oxidative stresses but did not affect the role of Yap1 in other stress responses and cellular functions. Carbon 16-17 DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C 130-134 31748248-4 2019 Deletion of the C-terminal cysteine-rich domain (c-CRD), where the nuclear export signal resides, increased nuclear enrichment of Yap1 under basal conditions and altered resistance to oxidative stresses but did not affect the role of Yap1 in other stress responses and cellular functions. Carbon 16-17 DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C 234-238 31748248-8 2019 Yap1 lacks an N-terminal cysteine-rich domain (n-CRD), which is present in other fungal Yap1 orthologs, but has a C-terminal cysteine-rich domain (c-CRD). Carbon 49-50 DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C 0-4 31749073-0 2019 Electrochemiluminescent immunoassay for neuron specific enolase by using amino-modified reduced graphene oxide loaded with N-doped carbon quantum dots. Carbon 131-137 enolase 2 Homo sapiens 40-63 31803219-4 2019 Our recent discovery of stomatal regulation by sugars that is mediated by guard-cell hexokinase (HXK), a sugar-sensing enzyme, has raised the possibility that HXK might be used to increase plant water-use efficiency (WUE; i.e., carbon gain per unit of water). Carbon 228-234 hexokinase 1 Homo sapiens 85-95 31803219-4 2019 Our recent discovery of stomatal regulation by sugars that is mediated by guard-cell hexokinase (HXK), a sugar-sensing enzyme, has raised the possibility that HXK might be used to increase plant water-use efficiency (WUE; i.e., carbon gain per unit of water). Carbon 228-234 hexokinase 1 Homo sapiens 97-100 31803219-4 2019 Our recent discovery of stomatal regulation by sugars that is mediated by guard-cell hexokinase (HXK), a sugar-sensing enzyme, has raised the possibility that HXK might be used to increase plant water-use efficiency (WUE; i.e., carbon gain per unit of water). Carbon 228-234 hexokinase 1 Homo sapiens 159-162 31580681-3 2019 Results revealed that the copper/carbon nanozymes exhibited copper state-dependent peroxidase-, catalase-, and superoxide dismutase-like activities. Carbon 33-39 catalase Homo sapiens 96-104 31737854-7 2019 Specifically, the adsorption of vitamin B12, a representative of middle molecular toxins in human blood, was about 3.7 mg g-1, which was acquired by simulated in vitro hemoperfusion tests and this demonstrated the promising application of the lotus root-type biomass-activated carbon in hemoperfusion. Carbon 277-283 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 40-43 31689955-9 2019 Here, we show that the absence of Asc1 resulted in massive exposure and accessibility of the C-terminal tail of its ribosomal neighbor Rps3 (uS3). Carbon 93-94 ribosomal 40S subunit protein S3 Saccharomyces cerevisiae S288C 135-139 31421177-2 2019 Herein, two enzymes acetylcholinesterase and choline oxidase were covalently immobilized over the gold nanoparticles (AuNPs) embedded graphene oxide (GO; 2D carbon material) nanocomposite modified ITO coated glass plate. Carbon 157-163 acetylcholinesterase (Cartwright blood group) Homo sapiens 20-40 30462864-2 2019 Herein, first a description of conventional molecular magnets coupled with sp2 carbon materials, such as carbon nanotubes and graphenes, is given. Carbon 79-85 Sp2 transcription factor Homo sapiens 75-78 30462864-2 2019 Herein, first a description of conventional molecular magnets coupled with sp2 carbon materials, such as carbon nanotubes and graphenes, is given. Carbon 105-111 Sp2 transcription factor Homo sapiens 75-78 30462864-3 2019 Then, progress on ferromagnetism in sp2 carbon nanomaterials due to the existence of defects or topological structures as the spin units, which makes the sp2 materials themselves act as a novel class of molecular magnets, is reviewed, and a scheme of controllable synthesis of the molecular magnets at the sheared ends of carbon nanotubes is proposed. Carbon 40-46 Sp2 transcription factor Homo sapiens 36-39 30462864-3 2019 Then, progress on ferromagnetism in sp2 carbon nanomaterials due to the existence of defects or topological structures as the spin units, which makes the sp2 materials themselves act as a novel class of molecular magnets, is reviewed, and a scheme of controllable synthesis of the molecular magnets at the sheared ends of carbon nanotubes is proposed. Carbon 40-46 Sp2 transcription factor Homo sapiens 154-157 30462864-3 2019 Then, progress on ferromagnetism in sp2 carbon nanomaterials due to the existence of defects or topological structures as the spin units, which makes the sp2 materials themselves act as a novel class of molecular magnets, is reviewed, and a scheme of controllable synthesis of the molecular magnets at the sheared ends of carbon nanotubes is proposed. Carbon 322-328 Sp2 transcription factor Homo sapiens 36-39 30462864-3 2019 Then, progress on ferromagnetism in sp2 carbon nanomaterials due to the existence of defects or topological structures as the spin units, which makes the sp2 materials themselves act as a novel class of molecular magnets, is reviewed, and a scheme of controllable synthesis of the molecular magnets at the sheared ends of carbon nanotubes is proposed. Carbon 322-328 Sp2 transcription factor Homo sapiens 154-157 31445206-9 2019 NMR studies revealed that there are two exchangeable hydrogens, one of which is on the alpha-carbon, justifying the carbon-centred edaravone radical produced from MPO. Carbon 93-99 myeloperoxidase Homo sapiens 163-166 31445206-9 2019 NMR studies revealed that there are two exchangeable hydrogens, one of which is on the alpha-carbon, justifying the carbon-centred edaravone radical produced from MPO. Carbon 116-122 myeloperoxidase Homo sapiens 163-166 31544921-4 2019 We identified an internal interaction between the WD40 propeller and the C-terminal distal region in RBBP5, which assisted the maintenance of the compact conformation of the MLL1 complex. Carbon 73-74 RB binding protein 5, histone lysine methyltransferase complex subunit Homo sapiens 101-106 31544921-5 2019 We also discovered a vertebrate-specific motif in the C-terminal distal region of RBBP5 that contributed to nucleosome recognition and methylation of nucleosomes by the MLL1 complex. Carbon 54-55 RB binding protein 5, histone lysine methyltransferase complex subunit Homo sapiens 82-87 31727786-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2, and EXO70F1. Carbon 22-23 exocyst subunit exo70 family protein F1 Arabidopsis thaliana 121-128 31545421-2 2019 Protein 4.1B/DAL-1 serves a crucial role in cytoskeletal organization and a number of processes through multiple interactions with membrane proteins via its FERM, spectrin-actin-binding and C-terminal domains. Carbon 190-191 erythrocyte membrane protein band 4.1 like 3 Homo sapiens 13-18 31323332-0 2019 Serine and one-carbon metabolism, a bridge that links mTOR signaling and DNA methylation in cancer. Carbon 15-21 mechanistic target of rapamycin kinase Homo sapiens 54-58 31323332-6 2019 Based on the latest understanding regarding the regulation of metabolic processes by mTOR signaling as well as interaction between metabolism and epigenetics, we further discuss how serine and one-carbon metabolism may serve as a bridge that links mTOR signaling and DNA methylation to promote tumor growth. Carbon 197-203 mechanistic target of rapamycin kinase Homo sapiens 248-252 31357360-0 2019 Nitrogen doped carbon dots for turn-off fluorescent detection of alkaline phosphatase activity based on inner filter effect. Carbon 15-21 alkaline phosphatase, placental Homo sapiens 65-85 31348615-1 2019 For sp2 or sp3 carbon material growth, it is important to investigate the precursors or intermediates just before growth. Carbon 15-21 Sp3 transcription factor Homo sapiens 11-14 31663294-1 2019 Graphene is a 2D sheet of sp2 bonded carbon atoms and tends to aggregate together, due to the strong pi-pi stacking and van der Waals attraction between different layers. Carbon 37-43 Sp2 transcription factor Homo sapiens 26-29 31358210-0 2019 Three-dimensional nitrogen-doped mesoporous carbon nanomaterials derived from plant biomass: Cost-effective construction of label-free electrochemical aptasensor for sensitively detecting alpha-fetoprotein. Carbon 44-50 alpha fetoprotein Homo sapiens 188-205 31421459-2 2019 Methylenetetrahydrofolate dehydrogenase 1 like (MTHFD1L), an enzyme in the folate cycle, is involved in formate generation and therefore in one-carbon metabolism. Carbon 144-150 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 0-41 31358226-6 2019 By the method of anodic stripping voltammetry, the Si@C-based electrode shows a very wide linear dynamic range for target ions (e.g., 0.5-400 mug L-1 for Cd(II) and Pb(II)) and low limit of detections (e.g., 0.068 mug L-1 for Cd(II) and for 0.105 mug L-1 Pb(II)). Carbon 54-55 submaxillary gland androgen regulated protein 3B Homo sapiens 165-171 31358226-6 2019 By the method of anodic stripping voltammetry, the Si@C-based electrode shows a very wide linear dynamic range for target ions (e.g., 0.5-400 mug L-1 for Cd(II) and Pb(II)) and low limit of detections (e.g., 0.068 mug L-1 for Cd(II) and for 0.105 mug L-1 Pb(II)). Carbon 54-55 submaxillary gland androgen regulated protein 3B Homo sapiens 255-261 31737034-8 2019 ALDH1L1, one of the folate-metabolizing enzymes, serves a regulatory function in folate metabolism restricting the flux of one-carbon groups through biosynthetic processes. Carbon 127-133 aldehyde dehydrogenase 1 family member L1 Homo sapiens 0-7 31673017-5 2019 In agreement with GSS activity localization in vivo, we identified six genes encoding arylsulfatase-like enzymes with a predicted C-terminal transmembrane domain, of which five showed GSS activity upon heterologous expression in insect cells. Carbon 130-131 glutathione synthetase Plutella xylostella 18-21 31673017-5 2019 In agreement with GSS activity localization in vivo, we identified six genes encoding arylsulfatase-like enzymes with a predicted C-terminal transmembrane domain, of which five showed GSS activity upon heterologous expression in insect cells. Carbon 130-131 glutathione synthetase Plutella xylostella 184-187 31553327-8 2019 Recently, the C-terminal fragment of pre-provasopressin, copeptin, has emerged to be a surrogate biomarker for AVP as it is more stable in the circulation. Carbon 14-15 arginine vasopressin Homo sapiens 111-114 31666507-4 2019 The results provide direct evidence that diamond surfaces are coated by sp2-, and sp3-bonded amorphous carbon and functional groups of carboxylic acids (e.g., carboxyl, carboxylate, methyl, and methylene), indicating the geosynthesis of organic compounds in deep hydrous fluids. Carbon 103-109 Sp3 transcription factor Homo sapiens 82-85 31666507-6 2019 As a possible scenario, with carbon saturation by reduction of carboxylate groups, I consider tetrahedral H-terminated C groups as templates for the growth of sp3-structured carbon. Carbon 29-35 Sp3 transcription factor Homo sapiens 159-162 31666507-6 2019 As a possible scenario, with carbon saturation by reduction of carboxylate groups, I consider tetrahedral H-terminated C groups as templates for the growth of sp3-structured carbon. Carbon 174-180 Sp3 transcription factor Homo sapiens 159-162 31781330-0 2019 New C-Terminal Conserved Regions of Tafazzin, a Catalyst of Cardiolipin Remodeling. Carbon 4-5 tafazzin, phospholipid-lysophospholipid transacylase Homo sapiens 36-44 31654277-0 2019 Green fluorescent carbon quantum dots functionalized with polyethyleneimine, and their application to aptamer-based determination of thrombin and ATP. Carbon 18-24 coagulation factor II, thrombin Homo sapiens 133-141 31657158-6 2019 The immunoactivity of TNF-alpha and IL-10 of the dorsal portion of the cervical spinal cord (C2-C5) was detected by immunofluorescence, and the expression of TNF-alpha, IL-10, IL-4 and IL-4 receptor (IL-4R) mRNAs was determined by quantitative real-time PCR. Carbon 93-98 tumor necrosis factor Rattus norvegicus 22-31 31649341-3 2019 ratio) nanoboxes supported on functionalized Vulcan carbon (Pt-Ni/C-R2) were synthesized through a facile method for the efficient electrooxidation of methanol. Carbon 52-58 complement C3d receptor 2 Homo sapiens 66-70 31844685-6 2019 The presence of the C-terminal regions of SIX3 and SIX6 proteins, but not their SIX domains or homeodomains as previously thought, were required for interaction with GEMININ. Carbon 20-21 SIX homeobox 3 Homo sapiens 42-46 31844685-7 2019 Interestingly, the disordered C- and N- terminal regions of GEMININ were involved in binding to SIX3/SIX6. Carbon 30-31 SIX homeobox 3 Homo sapiens 96-100 31781330-5 2019 Using bioinformatic methods, we have found conserved C-terminal regions in many tafazzin isoforms and identified new mammalian species that acquired exon 5 as well as rare occasions of intron retention between exons 8 and 9. Carbon 53-54 tafazzin, phospholipid-lysophospholipid transacylase Homo sapiens 80-88 31781330-6 2019 The regions in the C-terminal part arise from frameshifts relative to the full-length TAZ transcript after skipping exon 9 or retention of the intron between exons 10 and 11. Carbon 19-20 tafazzin, phospholipid-lysophospholipid transacylase Homo sapiens 86-89 31781330-9 2019 Arguably, unconventional tafazzin isoforms provide for the optimal balance between the increased biochemical activity of mitochondria (resulting from specific environmental or nutritional conditions) and lifespan maintenance; and the functional role of such isoforms is linked to the modification of the primary and secondary structures at their C-termini. Carbon 346-347 tafazzin, phospholipid-lysophospholipid transacylase Homo sapiens 25-33 31844685-0 2019 SIX3 and SIX6 interact with GEMININ via C-terminal regions. Carbon 40-41 SIX homeobox 3 Homo sapiens 0-4 31464077-4 2019 Compared to commercial Pt/C catalyst, the L10 -W-PtCo/C catalyst shows significant improvement in both initial activity and high-temperature stability. Carbon 0-1 immunoglobulin kappa variable 3-7 (non-functional) Homo sapiens 42-45 31832310-4 2019 Through binding to bromodomains and the phosphorylation-dependent interaction domain of bromodomain protein 4 (BRD4) via the C-terminus, GLTSCR1 blocks oncogenic transcriptional elongation. Carbon 125-126 bromodomain containing 4 Homo sapiens 88-109 31681773-3 2019 By expressing the two Er-MAPK1 domains tagged with the green fluorescent protein in mammalian fibroblasts, the yeast Schizosaccharomyces pombe and the ciliate Tetrahymena thermophila, evidence was obtained that the C-terminal domain contains all the sequence information responsible for the Er-MAPK1 subcellular localization. Carbon 215-216 mitogen-activated protein kinase 1 Homo sapiens 25-30 31637521-1 2019 A glassy carbon electrode (GCE) was coated with N-doped carbon-modified palygorskite and used as an electrochemical sensor for determination of Pb(II) by differential pulse anodic stripping voltammetry. Carbon 9-15 submaxillary gland androgen regulated protein 3B Homo sapiens 144-150 31637521-1 2019 A glassy carbon electrode (GCE) was coated with N-doped carbon-modified palygorskite and used as an electrochemical sensor for determination of Pb(II) by differential pulse anodic stripping voltammetry. Carbon 56-62 submaxillary gland androgen regulated protein 3B Homo sapiens 144-150 31832310-4 2019 Through binding to bromodomains and the phosphorylation-dependent interaction domain of bromodomain protein 4 (BRD4) via the C-terminus, GLTSCR1 blocks oncogenic transcriptional elongation. Carbon 125-126 bromodomain containing 4 Homo sapiens 111-115 31444841-0 2019 Construction of a sp3 /sp2 Carbon Interface in 3D N-Doped Nanocarbons for the Oxygen Reduction Reaction. Carbon 27-33 Sp3 transcription factor Homo sapiens 18-21 31530751-1 2019 Measured cross sections for the production of the PET isotopes C-10, C-11 and O-15 from carbon and oxygen targets induced by protons (40-220 MeV) and carbon ions (65-430 MeV/u) are presented. Carbon 88-94 homeobox C10 Homo sapiens 63-67 31530751-1 2019 Measured cross sections for the production of the PET isotopes C-10, C-11 and O-15 from carbon and oxygen targets induced by protons (40-220 MeV) and carbon ions (65-430 MeV/u) are presented. Carbon 150-156 homeobox C10 Homo sapiens 63-67 31473379-4 2019 Ni(OH)2 NCs@MnO2 NSs CSA modified glassy carbon electrode (GCE) exhibited two satisfying sensitivities of 467.1 and 1249.9 muA mM-1 cm-2 within the two linear ranges of 0.02-16.30 muM and 18.30-118.58 muM, respectively. Carbon 41-47 latexin Homo sapiens 180-183 31473379-4 2019 Ni(OH)2 NCs@MnO2 NSs CSA modified glassy carbon electrode (GCE) exhibited two satisfying sensitivities of 467.1 and 1249.9 muA mM-1 cm-2 within the two linear ranges of 0.02-16.30 muM and 18.30-118.58 muM, respectively. Carbon 41-47 latexin Homo sapiens 201-204 31351351-9 2019 PCB sorption tended to increase with the total organic carbon (TOC) of the particulate matter in the sediment samples. Carbon 55-61 pyruvate carboxylase Homo sapiens 0-3 31554399-3 2019 Co-catalyzed metal-hydride H atom transfer (MHAT) radical cyclization was utilized to form the C-ring and the all-carbon quaternary center at C-10. Carbon 114-120 homeobox C10 Homo sapiens 142-146 31571482-5 2019 Such Ln2@C80 molecules are unstable in the neutral form but can be stabilized by substitution of one carbon atom by nitrogen to give azafullerenes Ln2@C79N or by quenching the unpaired electron on the fullerene cage by reacting it with a chemical such as benzyl bromide, transforming one sp2 carbon into an sp3 carbon and yielding the monoadduct Ln2@C80(CH2Ph). Carbon 101-107 Sp2 transcription factor Homo sapiens 288-291 31571482-5 2019 Such Ln2@C80 molecules are unstable in the neutral form but can be stabilized by substitution of one carbon atom by nitrogen to give azafullerenes Ln2@C79N or by quenching the unpaired electron on the fullerene cage by reacting it with a chemical such as benzyl bromide, transforming one sp2 carbon into an sp3 carbon and yielding the monoadduct Ln2@C80(CH2Ph). Carbon 101-107 Sp3 transcription factor Homo sapiens 307-310 31571482-5 2019 Such Ln2@C80 molecules are unstable in the neutral form but can be stabilized by substitution of one carbon atom by nitrogen to give azafullerenes Ln2@C79N or by quenching the unpaired electron on the fullerene cage by reacting it with a chemical such as benzyl bromide, transforming one sp2 carbon into an sp3 carbon and yielding the monoadduct Ln2@C80(CH2Ph). Carbon 292-298 Sp2 transcription factor Homo sapiens 288-291 31571482-5 2019 Such Ln2@C80 molecules are unstable in the neutral form but can be stabilized by substitution of one carbon atom by nitrogen to give azafullerenes Ln2@C79N or by quenching the unpaired electron on the fullerene cage by reacting it with a chemical such as benzyl bromide, transforming one sp2 carbon into an sp3 carbon and yielding the monoadduct Ln2@C80(CH2Ph). Carbon 292-298 Sp3 transcription factor Homo sapiens 307-310 31571482-5 2019 Such Ln2@C80 molecules are unstable in the neutral form but can be stabilized by substitution of one carbon atom by nitrogen to give azafullerenes Ln2@C79N or by quenching the unpaired electron on the fullerene cage by reacting it with a chemical such as benzyl bromide, transforming one sp2 carbon into an sp3 carbon and yielding the monoadduct Ln2@C80(CH2Ph). Carbon 292-298 Sp2 transcription factor Homo sapiens 288-291 31571482-5 2019 Such Ln2@C80 molecules are unstable in the neutral form but can be stabilized by substitution of one carbon atom by nitrogen to give azafullerenes Ln2@C79N or by quenching the unpaired electron on the fullerene cage by reacting it with a chemical such as benzyl bromide, transforming one sp2 carbon into an sp3 carbon and yielding the monoadduct Ln2@C80(CH2Ph). Carbon 292-298 Sp3 transcription factor Homo sapiens 307-310 31617104-6 2019 In this study, ANG gene was fused with the C-terminal domain of single-chain antigen binding fragment (scFab) of the anti-VEGF antibody and recombinant scFab-ANG protein was expressed and purified using Rosatte (DE3) strain. Carbon 43-44 vascular endothelial growth factor A Homo sapiens 122-126 31444841-0 2019 Construction of a sp3 /sp2 Carbon Interface in 3D N-Doped Nanocarbons for the Oxygen Reduction Reaction. Carbon 27-33 Sp2 transcription factor Homo sapiens 23-26 31444841-2 2019 Herein, we demonstrate a facile approach to prepare three-dimensional (3D) N-doped carbon with a sp3 /sp2 carbon interface derived from ionic liquids via a simple pyrolysis process. Carbon 83-89 Sp3 transcription factor Homo sapiens 97-100 31444841-2 2019 Herein, we demonstrate a facile approach to prepare three-dimensional (3D) N-doped carbon with a sp3 /sp2 carbon interface derived from ionic liquids via a simple pyrolysis process. Carbon 83-89 Sp2 transcription factor Homo sapiens 102-105 31444841-2 2019 Herein, we demonstrate a facile approach to prepare three-dimensional (3D) N-doped carbon with a sp3 /sp2 carbon interface derived from ionic liquids via a simple pyrolysis process. Carbon 106-112 Sp2 transcription factor Homo sapiens 102-105 31444841-3 2019 The tunable hybrid sp3 and sp2 carbon composition and pore structures stem from the transformation of ionic liquids to polymerized organics and introduction of a Co metal salt. Carbon 31-37 Sp2 transcription factor Homo sapiens 27-30 31444841-4 2019 Through tuning both composition and pores, the 3D N-doped nanocarbon with a high sp3 /sp2 carbon ratio on the surface exhibits a superior electrocatalytic performance for the ORR compared to that of the commercial Pt/C in Zn-air batteries. Carbon 62-68 Sp3 transcription factor Homo sapiens 81-84 31444841-4 2019 Through tuning both composition and pores, the 3D N-doped nanocarbon with a high sp3 /sp2 carbon ratio on the surface exhibits a superior electrocatalytic performance for the ORR compared to that of the commercial Pt/C in Zn-air batteries. Carbon 62-68 Sp2 transcription factor Homo sapiens 86-89 31444841-5 2019 Density functional theory calculations suggest that the improved ORR performance can be ascribed to the existence of N dopants at the sp3 /sp2 carbon interface, which can lower the theoretical overpotential of the ORR. Carbon 143-149 Sp3 transcription factor Homo sapiens 134-137 31444841-5 2019 Density functional theory calculations suggest that the improved ORR performance can be ascribed to the existence of N dopants at the sp3 /sp2 carbon interface, which can lower the theoretical overpotential of the ORR. Carbon 143-149 Sp2 transcription factor Homo sapiens 139-142 31373413-4 2019 However, it is capable of rapidly transferring lithium ions and electrons owing to the large contact area with electrolyte and the high concentration sp2 -hybridized carbon coating. Carbon 166-172 Sp2 transcription factor Homo sapiens 150-153 31532667-0 2019 One-Step Facile Synthesis of Nitrogen-Doped Carbon Dots: A Ratiometric Fluorescent Probe for Evaluation of Acetylcholinesterase Activity and Detection of Organophosphorus Pesticides in Tap Water and Food. Carbon 44-50 acetylcholinesterase (Cartwright blood group) Homo sapiens 107-127 31532403-1 2019 We propose a new class of carbon allotropes obtained by combining linear sp carbon chains with sp3 bulk carbon. Carbon 26-32 Sp3 transcription factor Homo sapiens 95-98 31614616-2 2019 Syne-2 contains a C-terminal KASH transmembrane domain and is part of a protein network that associates the nuclear envelope to the cytoskeleton via the binding to actin filaments. Carbon 18-19 spectrin repeat containing, nuclear envelope 2 Mus musculus 0-6 31658734-3 2019 This study proposes the use of PdCl2 as a Pd precursor and activated carbon as the support to fabricate Pd/C catalytic materials (Pd/C-EP-Ar) by using ethanol-which is renewable, easily stored, and safe-combined with AP cold plasma (AP ethanol cold plasma) followed by calcination in Ar gas at 550 C for 2 h. Both Pd/C-EP and Pd/C-HP fabricated using AP ethanol and hydrogen cold plasma (without calcination in Ar gas) respectively, exhibit low CO oxidation reactivity. Carbon 69-75 ras homolog family member V Homo sapiens 330-334 31658734-4 2019 The activity of Pd/C-EP is lower than Pd/C-HP, which is mainly ascribed to the carbon layer formed by ethanol decomposition during plasma treatment. Carbon 79-85 ras homolog family member V Homo sapiens 41-45 31649623-5 2019 The MS analysis revealed IGF-1:Imp-L2 interactions which were not resolved in the crystal structure of this assembly, and they converged with X-ray results, indicating the importance of the IGF-1 N-terminus interaction with the C-terminal (185-242) part of the Imp-L2 for stability of this complex. Carbon 228-229 insulin like growth factor 1 Homo sapiens 190-195 31649651-2 2019 Our previous study has shown that PRRSV glycoprotein GP5 interacts with MYH9 C-terminal domain protein (PRA). Carbon 77-78 glycoprotein V platelet Homo sapiens 53-56 31649651-2 2019 Our previous study has shown that PRRSV glycoprotein GP5 interacts with MYH9 C-terminal domain protein (PRA). Carbon 77-78 myosin heavy chain 9 Homo sapiens 72-76 31649651-2 2019 Our previous study has shown that PRRSV glycoprotein GP5 interacts with MYH9 C-terminal domain protein (PRA). Carbon 77-78 S100 calcium binding protein A6 Homo sapiens 104-107 31646232-1 2019 The glassy carbon electrode was fabricated with multifunctional bis-triazole-appended calix[4]arene and then used for the simultaneous detection of Zn(II), Pb(II), As(III), and Hg(II). Carbon 11-17 submaxillary gland androgen regulated protein 3B Homo sapiens 156-162 31597329-9 2019 However, AMPK inhibitor Compound C pretreatment further promoted the inhibition of SA on autophagy induction and cell damage induced by OGD/R. Carbon 24-25 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 9-13 31646232-0 2019 Calix[4]arene Derivative-Modified Glassy Carbon Electrode: A New Sensing Platform for Rapid, Simultaneous, and Picomolar Detection of Zn(II), Pb(II), As(III), and Hg(II). Carbon 41-47 submaxillary gland androgen regulated protein 3B Homo sapiens 142-148 31594538-5 2019 Furthermore, we confirmed that the LSH-PKM2 interaction occurred at the intersubunit interface region of the PKM2 C-terminal region and the coiled-coil domains (CC) and ATP-binding domains of LSH, and this interaction regulated p53-mediated transactivation in cis in lipid metabolism, especially lipid catabolism. Carbon 114-115 helicase, lymphoid specific Homo sapiens 35-38 31586063-4 2019 Novel records of the isotopic composition of crenarchaeol constrain the global carbon isotope excursion magnitude to -4.0 +- 0.4%, consistent with emission of >3000 Pg C from methane hydrate dissociation or >4400 Pg C for scenarios involving emissions from geothermal heating or oxidation of sedimentary organic matter. Carbon 79-85 progastricsin Homo sapiens 165-169 31499002-0 2019 One-Pot Twofold Unsymmetrical C-Si Bond 2,6-Bifunctionalization of Arenes via Sequential [1,4]-Csp2 to O-Silyl Migration. Carbon 30-31 regulator of calcineurin 2 Homo sapiens 95-99 31499002-1 2019 Twofold unsymmetrical C-Si bond bifunctionalization of 2,6-di(trimethylsilyl) benzyl alcohols has been achieved in one pot via sequential [1,4]-Csp2 to O-silyl migration. Carbon 22-23 regulator of calcineurin 2 Homo sapiens 144-148 31556304-2 2019 The umpolung-like reactivity, between the alpha-carbon of tosylhydrazone and the 3-position of the heterocycle, which is observed in the obtained products, indicates the directed sp3-CH-activation of an alkylated phenol intermediate by the pendant 3-palladated heterocycle. Carbon 42-54 Sp3 transcription factor Homo sapiens 179-182 31586063-4 2019 Novel records of the isotopic composition of crenarchaeol constrain the global carbon isotope excursion magnitude to -4.0 +- 0.4%, consistent with emission of >3000 Pg C from methane hydrate dissociation or >4400 Pg C for scenarios involving emissions from geothermal heating or oxidation of sedimentary organic matter. Carbon 79-85 progastricsin Homo sapiens 213-217 31632276-0 2019 In Vivo Activation and Pro-Fibrotic Function of NF-kappaB in Fibroblastic Cells During Pulmonary Inflammation and Fibrosis Induced by Carbon Nanotubes. Carbon 134-140 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 48-57 31490648-5 2019 The high thiol content of THBP-n enables the formation of a network with a high degree of cross-linking between carbon nanotubes, which provides high-efficiency load transfer that increases the tensile strength and modulus of the resulting films and at the same time a compressible hyperbranched structure that allows for deformation and slip between CNTs and consequently improved elongation. Carbon 112-118 crystallin mu Homo sapiens 26-30 31222848-6 2019 Highly developed pi-conjugated electronic structures are common important features in GDY and graphene; however, the coexistence of sp and sp2 carbons differentiates GDY from graphene. Carbon 143-150 Sp2 transcription factor Homo sapiens 139-142 31514502-2 2019 We found that rhodium-carbynoid species provoke C(sp2)-C(sp2) bond scission in alkenes by inserting a monovalent carbon unit between both sp2-hybridized carbons. Carbon 113-119 Sp2 transcription factor Homo sapiens 48-53 31514502-2 2019 We found that rhodium-carbynoid species provoke C(sp2)-C(sp2) bond scission in alkenes by inserting a monovalent carbon unit between both sp2-hybridized carbons. Carbon 113-119 Sp2 transcription factor Homo sapiens 55-60 31514502-2 2019 We found that rhodium-carbynoid species provoke C(sp2)-C(sp2) bond scission in alkenes by inserting a monovalent carbon unit between both sp2-hybridized carbons. Carbon 113-119 Sp2 transcription factor Homo sapiens 50-53 31514502-2 2019 We found that rhodium-carbynoid species provoke C(sp2)-C(sp2) bond scission in alkenes by inserting a monovalent carbon unit between both sp2-hybridized carbons. Carbon 153-160 Sp2 transcription factor Homo sapiens 48-53 31514502-2 2019 We found that rhodium-carbynoid species provoke C(sp2)-C(sp2) bond scission in alkenes by inserting a monovalent carbon unit between both sp2-hybridized carbons. Carbon 153-160 Sp2 transcription factor Homo sapiens 55-60 31514502-2 2019 We found that rhodium-carbynoid species provoke C(sp2)-C(sp2) bond scission in alkenes by inserting a monovalent carbon unit between both sp2-hybridized carbons. Carbon 153-160 Sp2 transcription factor Homo sapiens 50-53 30773721-1 2019 Graphdiyne is a new member of the family of carbon-based nanomaterials that possess two types of carbon atoms, sp- and sp2 -hybridized carbon atoms. Carbon 44-50 Sp2 transcription factor Homo sapiens 119-122 31807524-13 2019 Photon and proton at 10 Gy increased the most ecto-CRT exposure (P<0.05), while carbon-ion increased most ecto-CRT exposure at 4 Gy rather than 10 or 2 Gy. Carbon 83-89 calreticulin Homo sapiens 114-117 31646216-2 2019 Because of the production process, various elemental impurities such as N, O, H, and so forth are inherent in interstitial sites or the surface carbon (sp2/amorphous) network. Carbon 144-150 Sp2 transcription factor Homo sapiens 152-155 31807524-15 2019 While carbon-ion has significantly stronger effects on increasing ecto-CRT than proton and photon at 2 and 4 Gy, but changed oppositely at 10 Gy (P<0.05). Carbon 6-12 calreticulin Homo sapiens 71-74 31807524-0 2019 Comparison of the effects of photon, proton and carbon-ion radiation on the ecto-calreticulin exposure in various tumor cell lines. Carbon 48-54 calreticulin Homo sapiens 81-93 31807524-4 2019 However, there is limited knowledge describing the effects of proton and carbon-ion radiation on ecto-CRT exposure. Carbon 73-79 calreticulin Homo sapiens 102-105 31807524-5 2019 Hence, we investigated ecto-CRT exposure in multiple human carcinoma cell lines irradiated by proton and carbon-ion in comparison to photon. Carbon 105-111 calreticulin Homo sapiens 28-31 31170652-7 2019 Treatment type and source of carbon were the operational factors with major significance on DBP production, especially in chlorination systems. Carbon 29-35 D-box binding PAR bZIP transcription factor Homo sapiens 92-95 31382095-1 2019 This work reported a ternary quenching strategy based on electrochemiluminescence resonance energy transfer (ECL-RET) between luminol/H2O2 system and MnO2 capped carbon nanospheres (MnO2@C) and Mn2+ released from the reduction of MnO2 and ascorbic acid (AA) consumed superoxide radical (O2 -) for detection of insulin. Carbon 162-168 insulin Homo sapiens 310-317 31102011-1 2019 Fructose is an important alternative carbon source for several tumors, and GLUT5 is the major fructose transporter which mediates most of fructose uptake in cells. Carbon 37-43 solute carrier family 2 member 5 Homo sapiens 75-80 31570332-0 2019 Detection of IgG antibodies to BP180 NC16a and C-terminal domains and LAD-1 in nivolumab-associated bullous pemphigoid. Carbon 38-39 collagen type XVII alpha 1 chain Homo sapiens 31-36 31392609-5 2019 Considering both pools, lower concentrations of DBPs were measured in the pool where a steady state non-purgeable organic carbon concentration was achieved, highlighting the importance of the establishment of a steady state balance of mineralisation versus addition of organic carbon to reduce precursors for DBP formation in pools. Carbon 122-128 D-box binding PAR bZIP transcription factor Homo sapiens 48-51 31392609-5 2019 Considering both pools, lower concentrations of DBPs were measured in the pool where a steady state non-purgeable organic carbon concentration was achieved, highlighting the importance of the establishment of a steady state balance of mineralisation versus addition of organic carbon to reduce precursors for DBP formation in pools. Carbon 277-283 D-box binding PAR bZIP transcription factor Homo sapiens 48-51 31396867-10 2019 eBC/EC ratios larger than one for both protocols were obtained, 1.62 (EUSAAR2) and 1.92 (NIOSH870), and also correlated with the ratio OC/EC for both protocols, especially in the cold season. Carbon 4-6 bone gamma-carboxyglutamate protein Homo sapiens 135-137 31625373-9 2019 Spearman"s correlation assay demonstrated that the correlation between the expression of miR-1296 and blood lipids, including TC, TG, HDL-c, and LDL-c, was TC (r = 0.4951, p = 0.0013), TG (r = 0.054, p = 0.6425), HDL-C (r = 0.3435, p = 0.07522), and LDL-C (r = 0.3307, p = 0.0699. Carbon 216-218 microRNA 1296 Homo sapiens 89-97 31302123-0 2019 Spectroscopic approach for the interaction of carbon nanoparticles with cytochrome c and BY-2 cells: Protein structure and mitochondrial function. Carbon 46-52 cytochrome c, somatic Homo sapiens 72-84 31302123-1 2019 In this study, we employed multiple spectroscopic methods to analyze the effects of carbon nanoparticles (CNPs) on structure of cytochrome c (Cyt c) and mitochondrial function in plant cells. Carbon 84-90 cytochrome c, somatic Homo sapiens 128-140 31302123-1 2019 In this study, we employed multiple spectroscopic methods to analyze the effects of carbon nanoparticles (CNPs) on structure of cytochrome c (Cyt c) and mitochondrial function in plant cells. Carbon 84-90 cytochrome c, somatic Homo sapiens 142-147 31548691-3 2019 Using structural and biochemical studies, along with reassessment of previous cryo-electron microscopy structures, we find that the C-terminal cholesterol attached to Sonic hedgehog (Shh) binds the first extracellular domain of PTCH1 and promotes its inactivation, thus triggering HH signaling. Carbon 132-133 patched 1 Homo sapiens 228-233 31581480-9 2019 Aspartate residues 487 and 441 were identified as caspase cleavage-sites in the C-terminal coiled-coil domain of human tricellulin. Carbon 80-81 MARVEL domain containing 2 Homo sapiens 119-130 31581480-11 2019 Deletion of the tricellulin C-terminal amino acids prevented binding to lipolysis-stimulated lipoprotein receptor (LSR)/angulin-1 and thus should impair specific localization of tricellulin to tTJs. Carbon 28-29 MARVEL domain containing 2 Homo sapiens 16-27 31581480-11 2019 Deletion of the tricellulin C-terminal amino acids prevented binding to lipolysis-stimulated lipoprotein receptor (LSR)/angulin-1 and thus should impair specific localization of tricellulin to tTJs. Carbon 28-29 MARVEL domain containing 2 Homo sapiens 178-189 31548691-5 2019 Thus, Shh inactivates PTCH1 by grasping its extracellular domain with two lipidic pincers, the N-terminal palmitate and the C-terminal cholesterol, which are both inserted into the PTCH1 protein core. Carbon 24-25 patched 1 Homo sapiens 181-186 31173100-8 2019 Furthermore, cep3-1 meristematic cells remained in S-phase longer than wild type cells during a sustained carbon (C)- and N-limitation. Carbon 106-116 Cysteine proteinases superfamily protein Arabidopsis thaliana 13-17 31453699-0 2019 BN-Doped Graphene and Single-Walled Carbon Nanotubes for the Catalysis of SN2 Reactions: Insights from Density Functional Theory Modeling. Carbon 36-42 solute carrier family 38 member 5 Homo sapiens 74-77 31453699-3 2019 The energy profile of the prototype Menshutkin SN2 reaction between ammonia and chloromethane has been analyzed in a variety of carbon-based materials at the DFT (density functional theory) level. Carbon 128-134 solute carrier family 38 member 5 Homo sapiens 47-50 31516609-4 2019 The objective of the present study was to investigate the effects of high-LET carbon ions and low-LET X-rays on the expression of VEGF and MMPs, and to identify the associated mechanisms in the Tca8113 TSCC cell line. Carbon 78-84 vascular endothelial growth factor A Homo sapiens 130-134 31516609-8 2019 These findings indicate that compared with low-LET X-ray irradiation, high-LET carbon ions possess higher biological efficacy in inhibiting the invasive ability of Tca8113 cells via reduction of VEGF, MMP-2 and MMP-9 expression. Carbon 79-85 vascular endothelial growth factor A Homo sapiens 195-199 31309671-1 2019 A highly efficient bifunctional metal-free catalyst was prepared by growth of three-dimensional porous fluorographdiyne networks on carbon cloth (p-FGDY/CC). Carbon 132-138 FYVE, RhoGEF and PH domain containing 1 Homo sapiens 148-152 31616255-2 2019 ELOVL4 is the only family member that catalyzes production of Very Long Chain Saturated Fatty Acids (VLC-SFA) and Very Long Chain Polyunsaturated Fatty Acids (VLC-PUFA) with chain lengths >=28 carbons. Carbon 193-200 ELOVL fatty acid elongase 4 Homo sapiens 0-6 31548257-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2 and EXO70F1. Carbon 22-23 exocyst subunit exo70 family protein F1 Arabidopsis thaliana 120-127 31546855-0 2019 Uniform Dispersion and Exfoliation of Multi-Walled Carbon Nanotubes in CNT-MgB2 Superconductor Composites Using Surfactants. Carbon 51-57 secretoglobin family 2A member 1 Homo sapiens 75-79 31420217-2 2019 Here, we find that lipopolysaccharide (LPS) activates the pentose phosphate pathway, the serine synthesis pathway, and one-carbon metabolism, the synergism of which drives epigenetic reprogramming for interleukin-1beta (IL-1beta) expression. Carbon 123-129 interleukin 1 beta Homo sapiens 201-218 31461267-2 2019 We herein report a multifunctional nanoplatform, carboxymethyl chitosan modified carbon nanoparticles (CMC@CNP), as the carrier for emamectin benzoate (EB, a widely used insecticide), and investigate its sustainable antipest activity. Carbon 81-87 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 107-110 31546937-3 2019 In this work, we functionalized the nanoclusters of carbon-coated iron nanoparticles with four proteins: bovine serum albumin, casein, and gelatins A and B, and we conducted a comprehensive comparative study of their properties essential to applications in biosensing. Carbon 52-58 albumin Homo sapiens 112-125 31667062-6 2019 Pharmacokinetic measurements confirmed appropriate plasma levels of drug in the saracatinib-treated group and Src inhibition was achieved clinically by a significant reduction in the bone resorption biomarker serum cross-linked C-terminal telopeptide of type I collagen. Carbon 228-229 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 110-113 31243973-9 2019 The second section highlights the use of readily available carbon nucleophiles possessing sp, sp2, and sp3 hybridization in a series of enantioselective carbon-carbon bond-forming reactions. Carbon 59-65 Sp2 transcription factor Homo sapiens 94-97 31243973-9 2019 The second section highlights the use of readily available carbon nucleophiles possessing sp, sp2, and sp3 hybridization in a series of enantioselective carbon-carbon bond-forming reactions. Carbon 59-65 Sp3 transcription factor Homo sapiens 103-106 31441649-6 2019 The results show this product is dominated by C18 carbon chain lengths, substituted with 3-7 chlorine atoms and 1-3 bromine atoms on an alkane chain. Carbon 50-56 Bardet-Biedl syndrome 9 Homo sapiens 46-49 31243973-9 2019 The second section highlights the use of readily available carbon nucleophiles possessing sp, sp2, and sp3 hybridization in a series of enantioselective carbon-carbon bond-forming reactions. Carbon 153-159 Sp2 transcription factor Homo sapiens 94-97 31243973-9 2019 The second section highlights the use of readily available carbon nucleophiles possessing sp, sp2, and sp3 hybridization in a series of enantioselective carbon-carbon bond-forming reactions. Carbon 153-159 Sp3 transcription factor Homo sapiens 103-106 31243973-9 2019 The second section highlights the use of readily available carbon nucleophiles possessing sp, sp2, and sp3 hybridization in a series of enantioselective carbon-carbon bond-forming reactions. Carbon 153-159 Sp2 transcription factor Homo sapiens 94-97 31243973-9 2019 The second section highlights the use of readily available carbon nucleophiles possessing sp, sp2, and sp3 hybridization in a series of enantioselective carbon-carbon bond-forming reactions. Carbon 153-159 Sp3 transcription factor Homo sapiens 103-106 31527496-0 2019 Intermolecular Non-Covalent Carbon-Bonding Interactions with Methyl Groups: A CSD, PDB and DFT Study. Carbon 28-34 PDB1 Homo sapiens 83-86 31411860-0 2019 sp2-sp3-Hybridized Atomic Domains Determine Optical Features of Carbon Dots. Carbon 64-70 Sp2 transcription factor Homo sapiens 0-3 31411860-0 2019 sp2-sp3-Hybridized Atomic Domains Determine Optical Features of Carbon Dots. Carbon 64-70 Sp3 transcription factor Homo sapiens 4-7 31411860-2 2019 Here, we show that all the distinctive optical properties of CDots, including the giant Stokes shift of photoluminescence and the strong dependence of emission color on excitation wavelength, can be explained by the linear optical response of the partially sp2-hybridized carbon domains located on the surface of the CDots" sp3-hybridized amorphous cores. Carbon 272-278 Sp2 transcription factor Homo sapiens 257-260 31411860-2 2019 Here, we show that all the distinctive optical properties of CDots, including the giant Stokes shift of photoluminescence and the strong dependence of emission color on excitation wavelength, can be explained by the linear optical response of the partially sp2-hybridized carbon domains located on the surface of the CDots" sp3-hybridized amorphous cores. Carbon 272-278 Sp3 transcription factor Homo sapiens 324-327 31527496-1 2019 A systematic evaluation of the CSD and the PDB in conjunction with DFT calculations reveal that non-covalent Carbon-bonding interactions with X-CH3 can be weakly directional in the solid state (P <= 1.5) when X = N or O. Carbon 109-115 PDB1 Homo sapiens 43-46 31170613-5 2019 After configuring with activated carbon, the asymmetric CDI cell exhibits excellent salt adsorption capacity of 17.46 mg g-1 at supplied voltage of 1.4 V when the feeding NaCl concentration is 300 mg L-1 and robust cycle performance with 81.4% capacity retention after 50 cycles at supplied voltage of 1.0 V with initial salt concentration of 500 mg L-1. Carbon 33-39 immunoglobulin kappa variable 1-16 Homo sapiens 200-203 31170613-5 2019 After configuring with activated carbon, the asymmetric CDI cell exhibits excellent salt adsorption capacity of 17.46 mg g-1 at supplied voltage of 1.4 V when the feeding NaCl concentration is 300 mg L-1 and robust cycle performance with 81.4% capacity retention after 50 cycles at supplied voltage of 1.0 V with initial salt concentration of 500 mg L-1. Carbon 33-39 immunoglobulin kappa variable 1-16 Homo sapiens 350-353 31220676-1 2019 In an effort to develop novel Bax activators for breast cancer treatment, a series of diverse analogues have been designed and synthesized based on lead compound SMBA1 through several strategies, including introducing various alkylamino side chains to have a deeper access to S184 pocket, replacing carbon atoms with nitrogen, and reducing the nitro group of 9H-fluorene scaffold. Carbon 299-305 BCL2 associated X, apoptosis regulator Homo sapiens 30-33 31583330-8 2019 MS studies indicate that HD5 binds near the L1 and L2 capsid proteins and specifically near the C-terminal region of L1. Carbon 96-97 defensin alpha 5 Homo sapiens 25-28 31572850-3 2019 Fluorescein isothiocyanate labeled bovine serum albumin was used for fouling studies and observed during cross-flow filtration operation for up to 144 h. Here, we mixed carbon nanotubes (CNTs) and polypropylene (PP) to make a spacer with better antifouling than plain PP spacers. Carbon 169-175 albumin Homo sapiens 42-55 31430154-4 2019 The induced nonplanarity can be ascribed to the fact that the carbon atoms of the CN groups prefer an sp3 hybridization in the S1 state. Carbon 62-68 Sp3 transcription factor Homo sapiens 102-105 31265848-0 2019 Preferential photochemical interaction of Ru (III) doped carbon nano dots with bovine serum albumin over human serum albumin. Carbon 57-63 albumin Homo sapiens 86-99 31265848-0 2019 Preferential photochemical interaction of Ru (III) doped carbon nano dots with bovine serum albumin over human serum albumin. Carbon 57-63 albumin Homo sapiens 111-124 31583330-9 2019 MD simulations indicate that favorable electrostatic interactions can be formed between HD5 and the L1 C-terminal tail. Carbon 103-104 defensin alpha 5 Homo sapiens 88-91 31121346-4 2019 The results indicated that a carbon-doped g-C3N4 with an optimum dopant content (MCB0.07) displayed the best photocatalytic activity for the total trihalomethanes (TTHM) and total haloacetonitriles (THAN), with the reaction rate constant of 11.6 and 10.4 (10-3 min-1), respectively. Carbon 29-35 CD59 molecule (CD59 blood group) Homo sapiens 261-266 31433943-0 2019 Bovine Serum Albumin Amplified Reactive Oxygen Species Generation from Anthrarufin-Derived Carbon Dot and Concomitant Nanoassembly for Combination Antibiotic-Photodynamic Therapy Application. Carbon 91-97 albumin Homo sapiens 7-20 31433943-1 2019 Amplification of reactive oxygen species (ROS) generation through covalent conjugation of bovine serum albumin (BSA) with newly synthesized, ROS-producing carbon dots (CDs) upon visible light irradiation is reported for the first time. Carbon 155-161 albumin Homo sapiens 97-110 33448841-0 2019 Sulforaphane-Conjugated Carbon Dots: A Versatile Nanosystem for Targeted Imaging and Inhibition of EGFR-Overexpressing Cancer Cells. Carbon 24-30 epidermal growth factor receptor Homo sapiens 99-103 31283103-2 2019 Size-selective microporous carbons (w<0.9 nm) with narrow pore size distribution are demonstrated to exclusively electrosorb small anions (BF4 - ) but size-exclude larger cations (TBA+ or TPA+ ), while the counter electrode, an ordered mesoporous carbon (w>2 nm), gives access to both ions. Carbon 27-34 plasminogen activator, tissue type Homo sapiens 191-195 31283103-2 2019 Size-selective microporous carbons (w<0.9 nm) with narrow pore size distribution are demonstrated to exclusively electrosorb small anions (BF4 - ) but size-exclude larger cations (TBA+ or TPA+ ), while the counter electrode, an ordered mesoporous carbon (w>2 nm), gives access to both ions. Carbon 27-33 plasminogen activator, tissue type Homo sapiens 191-195 31572837-11 2019 Spectroscopic data showed that the obtained carbon dots can detect Fe3+ ions within the wide concentration range of 30-600 muM with 9.55 muM detection limit. Carbon 44-50 latexin Homo sapiens 123-126 31572837-11 2019 Spectroscopic data showed that the obtained carbon dots can detect Fe3+ ions within the wide concentration range of 30-600 muM with 9.55 muM detection limit. Carbon 44-50 latexin Homo sapiens 137-140 31058370-6 2019 In the long-term, differences between N forms became less prevalent but higher recoveries in trees (particularly in the larch forest) of 15 NO3 - than 15 NH4 + tracer persisted, suggesting that incoming NO3 - may contribute more to plant biomass increment and forest carbon sequestration than incoming NH4 + . Carbon 267-273 NBL1, DAN family BMP antagonist Homo sapiens 203-206 31386358-3 2019 The oxidative degradation is achieved by efficient mediation of electron transfer from pollutants to persulfate through the sp2-hybridized carbon and nitrogen network. Carbon 139-145 Sp2 transcription factor Homo sapiens 124-127 31348572-2 2019 Herein, abundant MnO/Co heterointerfaces are engineered in porous graphitic carbon (MnO/Co/PGC) polyhedrons via a facile hydrothermal-calcination route with a bimetal-organic framework as the precursor. Carbon 76-82 progastricsin Homo sapiens 91-94 31209550-0 2019 Fluorescent probe based on carbon dots/silica/molecularly imprinted polymer for lysozyme detection and cell imaging. Carbon 27-33 lysozyme Homo sapiens 80-88 31403304-1 2019 A zirconium catalyzed reductive cleavage of Csp3 and Csp2 carbon-heteroatom bonds is reported that makes use of a tethered alkene functionality as a traceless directing group. Carbon 58-64 regulator of calcineurin 2 Homo sapiens 53-57 31433633-2 2019 Simultaneous formation of one C(sp3)-C(sp3) and one C(sp3)-C(sp2) bond across a variety of unbiased pi-systems proceeds with exquisite selectivity by the combination of a Ni catalyst with TDAE as sacrificial reductant. Carbon 30-31 Sp2 transcription factor Homo sapiens 59-64 31173860-4 2019 Here we reported an immersion subunit vaccine system (SWCNTs-MCP) encoding MCP gene of ISKNV based on single-walled carbon nanotubes (SWCNTs). Carbon 116-122 CD46 molecule Homo sapiens 61-64 31146239-1 2019 Graphene with atomic layer of sp2-hybridized carbon atoms in a hexagonal structure has attracted multidisciplinary attention since its discovery. Carbon 45-51 Sp2 transcription factor Homo sapiens 30-33 31273660-0 2019 Simultaneous removal of metronidazole and Pb(II) from aqueous solution onto bifunctional activated carbons. Carbon 99-106 submaxillary gland androgen regulated protein 3B Homo sapiens 42-48 31273660-8 2019 Finally, the mass transport of MNZ was faster than Pb(II) from the solution to the external surface of activated carbon and the mass flux of MNZ inside the particle was superior to the mass flux of Pb(II). Carbon 113-119 submaxillary gland androgen regulated protein 3B Homo sapiens 51-57 31273660-9 2019 Lastly, there might be an obstruction phenomenon with MNZ impeding Pb(II) to reach the active sites placed into the carbon"s microporosity structure. Carbon 116-122 submaxillary gland androgen regulated protein 3B Homo sapiens 67-73 31173860-4 2019 Here we reported an immersion subunit vaccine system (SWCNTs-MCP) encoding MCP gene of ISKNV based on single-walled carbon nanotubes (SWCNTs). Carbon 116-122 CD46 molecule Homo sapiens 75-78 31132435-3 2019 Crystal structure of the complex between human AChE and C-35 revealed tight contacts of ligand along the enzyme active site gorge. Carbon 0-1 acetylcholinesterase (Cartwright blood group) Homo sapiens 47-51 31012781-0 2019 Multi-walled carbon nanotubes (MWCNTs) promoted lipid accumulation in THP-1 macrophages through modulation of endoplasmic reticulum (ER) stress. Carbon 13-19 GLI family zinc finger 2 Homo sapiens 70-75 31012781-2 2019 Since ER stress is closely related to lipid droplet biogenesis, in this study, we investigated if multi-walled carbon nanotubes (MWCNTs) might influence lipid accumulation in THP-1 macrophages through the modulation of ER stress. Carbon 111-117 GLI family zinc finger 2 Homo sapiens 175-180 31171176-1 2019 In this work, a newly designed multifunctional adsorbent material, octadecyl-modified ordered mesoporous carbon (C18-CMK-8), was synthesized and employed for simultaneous analysis of multiple small molecules by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Carbon 105-111 Bardet-Biedl syndrome 9 Homo sapiens 113-116 31185326-5 2019 RESULTS: Modeling and a virtual screening analysis of FDX indicated that it is a stable protein with an iron-sulfur center that can discharge electrons produced from photo-excited Chl-a and transfers them to FDX-NADP+ reductase for NADP+ reduction in photosystem I, which is essential in the Calvin cycle for carbon assimilation. Carbon 309-315 petF Undaria pinnatifida 54-57 31185326-5 2019 RESULTS: Modeling and a virtual screening analysis of FDX indicated that it is a stable protein with an iron-sulfur center that can discharge electrons produced from photo-excited Chl-a and transfers them to FDX-NADP+ reductase for NADP+ reduction in photosystem I, which is essential in the Calvin cycle for carbon assimilation. Carbon 309-315 petF Undaria pinnatifida 208-211 31171195-0 2019 Colorimetric detection of ascorbic acid and alkaline phosphatase activity based on the novel oxidase mimetic of Fe-Co bimetallic alloy encapsulated porous carbon nanocages. Carbon 155-161 alkaline phosphatase, placental Homo sapiens 44-64 31171176-2 2019 The C18-CMK-8 was facilely prepared by one-step chemical binding of octadecyltrimethoxysilane to an ordered mesoporous carbon CMK-8. Carbon 119-125 Bardet-Biedl syndrome 9 Homo sapiens 4-7 31132562-10 2019 The SSAD system was a promising way to remove NO3- and PO43- simultaneously from wastewater lack of organic carbon sources. Carbon 108-114 NBL1, DAN family BMP antagonist Homo sapiens 46-49 31072477-0 2019 Near-infrared carbon dots-based fluorescence turn on aptasensor for determination of carcinoembryonic antigen in pleural effusion. Carbon 14-20 CEA cell adhesion molecule 3 Homo sapiens 85-109 31072477-2 2019 Herein, a novel fluorescence aptasensor with high signal-noise ratio (SNR) was constructed to achieve highly-sensitive detection of CEA relied upon the fluorescence resonance energy transfer (FRET) between near-infrared carbon dots (NIR-CDs) and gold nanorods (AuNRs). Carbon 220-226 CEA cell adhesion molecule 3 Homo sapiens 132-135 31471765-0 2019 Electrochemical thrombin aptasensor based on using magnetic nanoparticles and porous carbon prepared by carbonization of a zinc(II)-2-methylimidazole metal-organic framework. Carbon 85-91 coagulation factor II, thrombin Homo sapiens 16-24 31461438-5 2019 Mechanistically, glucose catabolism in CDCP1+ CSCs is routed to the oxidative pentose phosphate pathway (PPP); multiple cycling of carbon backbones in the oxidative PPP potentially maximizes NADPH reduction to counteract chemotherapy-induced reactive oxygen species (ROS) formation, thereby allowing CDCP1+ CSCs to survive chemotherapeutic attack. Carbon 131-137 CUB domain containing protein 1 Rattus norvegicus 39-44 31461438-5 2019 Mechanistically, glucose catabolism in CDCP1+ CSCs is routed to the oxidative pentose phosphate pathway (PPP); multiple cycling of carbon backbones in the oxidative PPP potentially maximizes NADPH reduction to counteract chemotherapy-induced reactive oxygen species (ROS) formation, thereby allowing CDCP1+ CSCs to survive chemotherapeutic attack. Carbon 131-137 CUB domain containing protein 1 Rattus norvegicus 300-305 31381849-0 2019 Brightening of Long, Polymer-Wrapped Carbon Nanotubes by sp3 Functionalization in Organic Solvents. Carbon 37-43 Sp3 transcription factor Homo sapiens 57-60 31381849-1 2019 The functionalization of semiconducting single-walled carbon nanotubes (SWNTs) with sp3 defects that act as luminescent exciton traps is a powerful means to enhance their photoluminescence quantum yield (PLQY) and to add optical properties. Carbon 54-60 Sp3 transcription factor Homo sapiens 84-87 31082594-4 2019 The key objective of the present work is to conduct a feasibility study for the conversion of CAs (TSP and PM10) into a value-added carbon nanostructured product by using a chemical method. Carbon 132-138 thrombospondin 1 Homo sapiens 99-102 31339693-6 2019 In organometallic compounds, a large deshielding of the isotropic carbon-13 chemical shift of the metal-bonded carbon atom is commonly related to the coupling between the occupied sigmaM-C orbital and low-lying vacant orbitals of piM C* character. Carbon 66-72 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 230-233 31339693-6 2019 In organometallic compounds, a large deshielding of the isotropic carbon-13 chemical shift of the metal-bonded carbon atom is commonly related to the coupling between the occupied sigmaM-C orbital and low-lying vacant orbitals of piM C* character. Carbon 111-117 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 230-233 31339693-7 2019 The deshielding at the alpha-carbon hence probes the extent of sigmaM-C and piM C* interactions. Carbon 29-35 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 76-79 31438892-0 2019 Reduction of metastatic potential by inhibiting EGFR/Akt/p38/ERK signaling pathway and epithelial-mesenchymal transition after carbon ion exposure is potentiated by PARP-1 inhibition in non-small-cell lung cancer. Carbon 127-133 poly(ADP-ribose) polymerase 1 Homo sapiens 165-171 31248773-3 2019 Interestingly, introduction of an alkyl group into the carbon atom of the m-carborane cage of 3a markedly enhanced the binding affinity toward ERalpha and decreased affinity toward ERbeta. Carbon 55-61 estrogen receptor 1 Homo sapiens 143-150 31310121-3 2019 These transition-metal-free radical chain reactions enable the efficient formation of C-C, C-S, and C-P bonds through homolytic aromatic substitution or SRN1 reactions. Carbon 86-87 NPHS2 stomatin family member, podocin Homo sapiens 153-157 31248773-3 2019 Interestingly, introduction of an alkyl group into the carbon atom of the m-carborane cage of 3a markedly enhanced the binding affinity toward ERalpha and decreased affinity toward ERbeta. Carbon 55-61 estrogen receptor 1 Homo sapiens 181-187 31281020-2 2019 Compound 10j, which is tacrine linked with pyrazolo[3,4-b]pyridine moiety by a six-carbon spacer, was the most potent acetylcholinesterase (AChE) with IC50 value of 0.125 muM. Carbon 83-89 acetylcholinesterase (Cartwright blood group) Homo sapiens 118-138 31398794-7 2019 The qualitative analysis of degradation products confirmed the involvement of hydroxyl radical and sulfate radical and figured out that the active sites of ACE were the C=C bond, ether bond, and C-N bond. Carbon 169-170 angiotensin I converting enzyme Homo sapiens 156-159 31497710-1 2019 In this study, we investigate the adsorption capability of molybdenum sulfide (MoS2)/thiol-functionalized multiwalled carbon nanotube (SH-MWCNT) nanocomposite for rapid and efficient removal of heavy metals [Pb(II) and Cd(II)] from industrial mine water. Carbon 118-124 submaxillary gland androgen regulated protein 3B Homo sapiens 208-214 31398794-7 2019 The qualitative analysis of degradation products confirmed the involvement of hydroxyl radical and sulfate radical and figured out that the active sites of ACE were the C=C bond, ether bond, and C-N bond. Carbon 169-170 angiotensin I converting enzyme Homo sapiens 156-159 31390846-7 2019 Experimental results proved that elevated NOM (6.14 mg L-1 as Total Organic Carbon, TOC) in raw water was the root cause for the failure of the plant while the low temperature played a minor but significant role. Carbon 76-82 immunoglobulin kappa variable 1-16 Homo sapiens 55-58 31334508-2 2019 We employed activity-based protein profiling (ABPP) to show that the secondary-carbon-centered radical of 1,2,4-trioxolanes is primarily responsible for protein labeling in malaria parasites. Carbon 79-85 amyloid beta precursor protein Homo sapiens 46-50 31391321-4 2019 Mutations in EGFR or PTEN generated distinct CAD phosphorylation patterns to activate carbon influx through pyrimidine synthesis. Carbon 86-92 epidermal growth factor receptor Homo sapiens 13-17 31054527-1 2019 The aggregation, deposition and porous retention of bovine serum albumin treated multi-walled carbon nanotubes (BSA-MWCNTs) are investigated using dynamic light scattering (DLS), quartz crystal microbalance with dissipation (QCM-D) and 2-dimensional silicon micromodel, respectively. Carbon 94-100 albumin Homo sapiens 59-72 31061298-0 2019 A Probe for Fluorescence Detection of the Acetylcholinesterase Activity Based on Molecularly Imprinted Polymers Coated Carbon Dots. Carbon 119-125 acetylcholinesterase (Cartwright blood group) Homo sapiens 42-62 31158577-6 2019 Amongst them, 7k, 7m and 7p, all with a 6 carbon linker between tacrine and isatin Schiff base exhibited the strongest inhibitory activity against AChE with IC50 values of 0.42 nM, 0.62 nM and 0.95 nM, respectively. Carbon 42-48 acetylcholinesterase (Cartwright blood group) Homo sapiens 147-151 31428598-1 2019 The reactivity of CO 2 + with CD4 has been experimentally investigated for its relevance in the chemistry of plasmas used for the conversion of CO2 in carbon-neutral fuels. Carbon 154-160 CD4 molecule Homo sapiens 33-36 30741559-1 2019 We established a murine model of multiwall carbon nanotube (MWCNT)-elicited chronic granulomatous disease that bears similarities to human sarcoidosis pathology, including alveolar macrophage deficiency of peroxisome proliferator-activated receptor gamma (PPARgamma). Carbon 43-49 peroxisome proliferator activated receptor gamma Homo sapiens 206-254 30741559-1 2019 We established a murine model of multiwall carbon nanotube (MWCNT)-elicited chronic granulomatous disease that bears similarities to human sarcoidosis pathology, including alveolar macrophage deficiency of peroxisome proliferator-activated receptor gamma (PPARgamma). Carbon 43-49 peroxisome proliferator activated receptor gamma Homo sapiens 256-265 30898039-0 2019 Loss of Rim15p in shochu yeast alters carbon utilization during barley shochu fermentation. Carbon 38-44 protein kinase RIM15 Saccharomyces cerevisiae S288C 8-14 30898039-3 2019 The disruptant did not improve ethanol yield, but altered sugar and glycerol contents in the mash, suggesting that Rim15p has a novel function in carbon utilization. Carbon 146-152 protein kinase RIM15 Saccharomyces cerevisiae S288C 115-121 31061298-1 2019 This paper presents a new probe for fluorescence detection of the acetylcholinesterase (AChE) activity based on molecularly imprinted polymer (MIP) coated carbon dots (C-dots) composite. Carbon 155-161 acetylcholinesterase (Cartwright blood group) Homo sapiens 66-86 31061298-1 2019 This paper presents a new probe for fluorescence detection of the acetylcholinesterase (AChE) activity based on molecularly imprinted polymer (MIP) coated carbon dots (C-dots) composite. Carbon 155-161 acetylcholinesterase (Cartwright blood group) Homo sapiens 88-92 31280571-0 2019 Tailoring the Adsorption of ACE-Inhibiting Peptides by Nitrogen Functionalization of Porous Carbons. Carbon 92-99 angiotensin I converting enzyme Homo sapiens 28-31 31234261-0 2019 Ultra-fast enrichment and reduction of As(V)/Se(VI) on three dimensional graphene oxide sheets-oxidized carbon nanotubes hydrogels. Carbon 104-110 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 39-44 31381950-9 2019 Overall, this study suggests that the fetal liver Mll-AF4+ LSK cells are sensitive to direct exposure to inflammatory stimuli, especially poly(I:C); however, maternal immune activation induced by a single exposure to poly(I:C) is not sufficient to initiate MLL-AF4 leukemogenesis. Carbon 145-147 lysine (K)-specific methyltransferase 2A Mus musculus 50-53 30939054-1 2019 Background: The aim of this report was dual: (a) to describe the step-by-step standardized intraoperative percutaneous injection of carbon nanoparticles (CNPs) procedure for CNP-stained central compartment lymph nodes (CLNs) and passive display of parathyroid gland by CNP-stained thyroid in endoscopic thyroidectomy via bilateral areola approach (ETBAA) and (b) evaluation and outcomes of percutaneous injection of CNPs in total thyroidectomy plus CLN dissection through ETBAA. Carbon 132-138 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 154-157 30939054-1 2019 Background: The aim of this report was dual: (a) to describe the step-by-step standardized intraoperative percutaneous injection of carbon nanoparticles (CNPs) procedure for CNP-stained central compartment lymph nodes (CLNs) and passive display of parathyroid gland by CNP-stained thyroid in endoscopic thyroidectomy via bilateral areola approach (ETBAA) and (b) evaluation and outcomes of percutaneous injection of CNPs in total thyroidectomy plus CLN dissection through ETBAA. Carbon 132-138 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 174-177 31322875-2 2019 Due to the electronic bias of the pi-alkene-palladium complexes, nucleopalladations with terminal aliphatic alkenes typically deliver the nucleophile to the more substituted sp2 carbon to form the Markovnikov-selective products. Carbon 178-184 Sp2 transcription factor Homo sapiens 174-177 31145518-7 2019 Redundancy analysis demonstrated that comammox clade A.1 was negatively correlated with total carbon and ammonium concentrations, whereas the opposite was observed in AOB. Carbon 94-100 BCL2 related protein A1 Homo sapiens 53-56 31169974-3 2019 This collection has reduced complexity and better synthetic accessibility than the entire GDB17 but retains higher sp3 -carbon fraction and natural product likeness scores compared to known drugs. Carbon 120-126 Sp3 transcription factor Homo sapiens 115-118 31036225-0 2019 A chemiluminescence biosensor for lysozyme detection based on aptamers and hemin/G-quadruplex DNAzyme modified sandwich-rod carbon fiber composite. Carbon 124-130 lysozyme Homo sapiens 34-42 31036225-1 2019 In our work, aptamers and hemin/G-quadruplex DNAzyme modified sandwich-rod graphene quantum dots @ graphene oxide @ carbon fiber composite (DNAzyme/L-Apt/GQDs@GO@CF) was successfully prepared for sensitive and selective chemiluminescence (CL) detection of lysozyme (LZM). Carbon 116-122 lysozyme Homo sapiens 256-264 31036225-1 2019 In our work, aptamers and hemin/G-quadruplex DNAzyme modified sandwich-rod graphene quantum dots @ graphene oxide @ carbon fiber composite (DNAzyme/L-Apt/GQDs@GO@CF) was successfully prepared for sensitive and selective chemiluminescence (CL) detection of lysozyme (LZM). Carbon 116-122 lysozyme Homo sapiens 266-269 31036225-5 2019 Then, the modified sandwich-rod carbon fiber composite was applied to the construction of CL biosensor for LZM detection. Carbon 32-38 lysozyme Homo sapiens 107-110 31661443-6 2019 The concentrations of the two odorants could be reduced from 500 ng L-1 to less than 10 ng L-1 with the presence of NOM (<20 mg L-1 total organic carbon, TOC). Carbon 149-155 immunoglobulin kappa variable 1-16 Homo sapiens 68-71 31661443-6 2019 The concentrations of the two odorants could be reduced from 500 ng L-1 to less than 10 ng L-1 with the presence of NOM (<20 mg L-1 total organic carbon, TOC). Carbon 149-155 immunoglobulin kappa variable 1-16 Homo sapiens 91-94 31661443-6 2019 The concentrations of the two odorants could be reduced from 500 ng L-1 to less than 10 ng L-1 with the presence of NOM (<20 mg L-1 total organic carbon, TOC). Carbon 149-155 immunoglobulin kappa variable 1-16 Homo sapiens 91-94 30967187-1 2019 Herein, combined with the outstanding adsorption ability of flower-like MoS2 with ultra-thin nanosheets and the good electrical conductivity of reduced graphene oxide (rGO), a sensitive and anti-interference electrochemical sensing interface for the analysis of Pb(II) was constructed by using MoS2/rGO nanocomposite modified glassy carbon electrode (MoS2/rGO-GCE). Carbon 333-339 submaxillary gland androgen regulated protein 3B Homo sapiens 262-268 31280571-3 2019 This study focuses on the impact of nitrogen functionalization of porous carbon adsorbents, either via pre- or post-treatment, on the adsorption behavior of the ACE-inhibiting peptide IW and the essential amino acid tryptophan (W). Carbon 73-79 angiotensin I converting enzyme Homo sapiens 161-164 31280571-9 2019 The treatment with the three different carbon materials leads to an increase in the ACE-inhibiting effect in vitro. Carbon 39-45 angiotensin I converting enzyme Homo sapiens 84-87 31276143-0 2019 Probing Ca2+-induced conformational change of calmodulin with gold nanoparticle-decorated single-walled carbon nanotube field-effect transistors. Carbon 104-110 calmodulin 1 Homo sapiens 46-56 31363918-0 2019 Carbon dots co-doped with nitrogen and chlorine for "off-on" fluorometric determination of the activity of acetylcholinesterase and for quantification of organophosphate pesticides. Carbon 0-6 acetylcholinesterase (Cartwright blood group) Homo sapiens 107-127 31339941-6 2019 Carbon stock in aboveground woody biomass increased from 6 Mg ha-1 in the vineyard to 105 Mg ha-1 in old growth forest. Carbon 0-6 Rho GTPase activating protein 45 Homo sapiens 62-66 31186346-6 2019 We attributed a decreased carbon flux from glucose to acetyl-CoA in the TAZ-KO cells to a ~50% decrease in pyruvate dehydrogenase (PDH) activity, which was observed in both TAZ-KO cells and cardiac tissue from TAZ-KO mice. Carbon 26-32 tafazzin, phospholipid-lysophospholipid transacylase Mus musculus 72-75 31339941-6 2019 Carbon stock in aboveground woody biomass increased from 6 Mg ha-1 in the vineyard to 105 Mg ha-1 in old growth forest. Carbon 0-6 Rho GTPase activating protein 45 Homo sapiens 93-97 31339941-7 2019 Along the secondary succession, soil carbon considerably increased from about 33 Mg ha-1 in the vineyard to about 69 Mg ha-1 in old growth forest. Carbon 37-43 Rho GTPase activating protein 45 Homo sapiens 84-88 31339941-7 2019 Along the secondary succession, soil carbon considerably increased from about 33 Mg ha-1 in the vineyard to about 69 Mg ha-1 in old growth forest. Carbon 37-43 Rho GTPase activating protein 45 Homo sapiens 120-124 31339941-12 2019 Overall, carbon stock in aboveground woody biomass, litter and soil increased from about 48 Mg ha-1 in the vineyard to about 198 Mg ha-1 in old growth forest. Carbon 9-15 Rho GTPase activating protein 45 Homo sapiens 95-99 31339941-12 2019 Overall, carbon stock in aboveground woody biomass, litter and soil increased from about 48 Mg ha-1 in the vineyard to about 198 Mg ha-1 in old growth forest. Carbon 9-15 Rho GTPase activating protein 45 Homo sapiens 132-136 31312984-4 2019 In this study, the N- and alpha-carbon oxidation processes of lapatinib catalyzed by CYP3A4 were explored by density functional theory method. Carbon 32-38 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 85-91 31150773-1 2019 Vitamin B12 plays an essential role in one-carbon metabolism in the human body. Carbon 43-49 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 8-11 31164198-0 2019 Degradation of pristine and oxidized single wall carbon nanotubes by CYP3A4. Carbon 49-55 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 69-75 31164198-3 2019 In the present investigation, we studied the biodegradation of single-walled carbon nanotubes (SWCNTs) by Cytochrome P450 enzymes (CYP3A4) through using Raman spectroscopy. Carbon 77-83 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 131-137 31106469-2 2019 Herein, we report a wall- and hybridisation-selective synthetic methodology to produce double-walled carbon nanotubes with an inner tube doped exclusively with graphitic sp2 -nitrogen atoms. Carbon 101-107 Sp2 transcription factor Homo sapiens 170-173 31319869-7 2019 A poly(I:C) model was also used to further understand the molecular mechanism by which MEK controls IFN response. Carbon 9-11 mitogen-activated protein kinase kinase 7 Homo sapiens 87-90 31085401-3 2019 Herein, a highly sensitive and selective aptasensor for quantitative detection of interleukin-6 was developed by using a glassy carbon electrode modified with p-aminobenzoic acid, p-aminothiophenol and gold nanoparticles. Carbon 128-134 interleukin 6 Homo sapiens 82-95 31087744-0 2019 Diamondoid Nanostructures as sp3 -Carbon-Based Gas Sensors. Carbon 34-40 Sp3 transcription factor Homo sapiens 29-32 30986685-8 2019 The chiA and nifH abundances decreased with soil depth and were associated with variation in aboveground biomass, NH4+-N, and organic carbon, while amoA-AOA, nirK, and nirS genes increased with depth and were more affected by soil organic carbon, moisture, and bulk density. Carbon 134-140 chitinase acidic Homo sapiens 4-8 31302781-10 2019 Graphical abstract Schematic presentation of a sandwich-type electrochemical aptasensor based on nitrogen doped graphene (NG), gold nanoparticles (AuNPs) and graphene quantum dots (GQDs) modified glassy carbon electrode, and the hemin-G4 DNAzyme for femtomolar detection of the carcinoembryonic antigen. Carbon 203-209 CEA cell adhesion molecule 3 Homo sapiens 278-302 30954801-1 2019 Carbon dots (C-dots) were used to study the binding mechanisms with serum protein, bovine serum albumin (BSA) by using two notable binding systems known as non-covalent and covalent interaction. Carbon 0-6 albumin Homo sapiens 90-103 31292460-0 2019 A dual-model SERS and RRS analytical platform for Pb(II) based on Ag-doped carbon dot catalytic amplification and aptamer regulation. Carbon 75-81 submaxillary gland androgen regulated protein 3B Homo sapiens 50-56 31190539-3 2019 This is the first example of using TIPS-EBX for the transformation of C(sp) to either C(sp2) or C(sp3) under metal-free conditions. Carbon 70-71 Sp2 transcription factor Homo sapiens 86-91 31854701-5 2019 The results showed that the average concentrations of organic carbon in the waters of the Miaowei, Gongguoqiao, and Dachaoshan Reservoirs were 0.95 mg L-1, 1.97 mg L-1, and 4.64 mg L-1, respectively. Carbon 62-68 immunoglobulin kappa variable 1-16 Homo sapiens 151-154 31854701-5 2019 The results showed that the average concentrations of organic carbon in the waters of the Miaowei, Gongguoqiao, and Dachaoshan Reservoirs were 0.95 mg L-1, 1.97 mg L-1, and 4.64 mg L-1, respectively. Carbon 62-68 immunoglobulin kappa variable 1-16 Homo sapiens 164-167 31854701-5 2019 The results showed that the average concentrations of organic carbon in the waters of the Miaowei, Gongguoqiao, and Dachaoshan Reservoirs were 0.95 mg L-1, 1.97 mg L-1, and 4.64 mg L-1, respectively. Carbon 62-68 immunoglobulin kappa variable 1-16 Homo sapiens 164-167 30958921-5 2019 This Minireview provides a short overview of the major progress made in this field for C-H functionalization at sp2 and sp3 carbon centers with different transient working modes, including covalent, hydrogen, and ionic bonds. Carbon 124-130 Sp3 transcription factor Homo sapiens 120-123 31199655-1 2019 The addition of a carbene catalyst to an indole aryl aldehyde leads to the activation of a remote sp2 carbon that is five atoms away from the catalyst. Carbon 102-108 Sp2 transcription factor Homo sapiens 98-101 31199655-0 2019 Addition of a Carbene Catalyst to Indole Aryl Aldehyde Activates a Remote delta-sp2 Carbon for Protonation and Formal [4+2] Reaction. Carbon 84-90 Sp2 transcription factor Homo sapiens 80-83 31270632-12 2019 Graphical abstract Schematic presentation of the quenching of the fluorescence of phosphorus and nitrogen dually-doped carbon quantum dots (PN-CQDs) by vitamin B12 (VB12) and Co(II). Carbon 119-125 mitochondrially encoded cytochrome c oxidase II Homo sapiens 175-181 31270625-0 2019 Electrochemiluminescent immunoassay for insulin by using a quencher pair consisting of CdS:Eu nanoclusters loaded with multiwalled carbon nanotubes on reduced graphene oxide nanoribbons and gold nanoparticle-loaded octahedral Cu2O. Carbon 131-137 insulin Homo sapiens 40-47 31270702-0 2019 Impedimetric aptasensing of the breast cancer biomarker HER2 using a glassy carbon electrode modified with gold nanoparticles in a composite consisting of electrochemically reduced graphene oxide and single-walled carbon nanotubes. Carbon 76-82 erb-b2 receptor tyrosine kinase 2 Homo sapiens 56-60 31270702-0 2019 Impedimetric aptasensing of the breast cancer biomarker HER2 using a glassy carbon electrode modified with gold nanoparticles in a composite consisting of electrochemically reduced graphene oxide and single-walled carbon nanotubes. Carbon 214-220 erb-b2 receptor tyrosine kinase 2 Homo sapiens 56-60 31270702-9 2019 Graphical abstract An electrochemical aptasensor for HER2 is described that is based on the immobilization of anti-HER2 aptamer on a glassy carbon electrode modified with a nanocomposite prepred fromreduced graphene oxide, carbon nanotubes and gold nanoparticles. Carbon 140-146 erb-b2 receptor tyrosine kinase 2 Homo sapiens 53-57 31270702-9 2019 Graphical abstract An electrochemical aptasensor for HER2 is described that is based on the immobilization of anti-HER2 aptamer on a glassy carbon electrode modified with a nanocomposite prepred fromreduced graphene oxide, carbon nanotubes and gold nanoparticles. Carbon 140-146 erb-b2 receptor tyrosine kinase 2 Homo sapiens 115-119 31270702-9 2019 Graphical abstract An electrochemical aptasensor for HER2 is described that is based on the immobilization of anti-HER2 aptamer on a glassy carbon electrode modified with a nanocomposite prepred fromreduced graphene oxide, carbon nanotubes and gold nanoparticles. Carbon 223-229 erb-b2 receptor tyrosine kinase 2 Homo sapiens 53-57 31270702-9 2019 Graphical abstract An electrochemical aptasensor for HER2 is described that is based on the immobilization of anti-HER2 aptamer on a glassy carbon electrode modified with a nanocomposite prepred fromreduced graphene oxide, carbon nanotubes and gold nanoparticles. Carbon 223-229 erb-b2 receptor tyrosine kinase 2 Homo sapiens 115-119 31274439-7 2019 The SXR curve of the contaminated mirror shows a clear dip near the critical momentum transfer of carbon, indicating the presence of carbon contamination on the mirror surface. Carbon 98-104 nuclear receptor subfamily 1 group I member 2 Homo sapiens 4-7 30761735-7 2019 Moreover, one pex16 allele exhibited reduced growth that could be alleviated by an external fixed carbon source, decreased responsiveness to peroxisomally processed hormone precursors, and worsened or improved peroxisome function in combination with other pex mutants. Carbon 98-104 shrunken seed protein (SSE1) Arabidopsis thaliana 14-19 30338915-0 2019 Key Factors for Simultaneous Improvements of Performance and Durability of Core-Shell Pt3 Ni/Carbon Electrocatalysts Toward Superior Polymer Electrolyte Fuel Cell. Carbon 93-99 zinc finger protein 135 Homo sapiens 86-89 30338915-2 2019 In this account we found double-promotional effects of carbon micro coil (CMC) support on ORR performance and durability of octahedral Pt3 Ni nanoparticles (Oh Pt3 Ni/CMC). Carbon 55-61 zinc finger protein 135 Homo sapiens 135-138 30338915-6 2019 Key factors for simultaneous improvements of performance and durability of core-shell Pt3 Ni/carbon electrocatalysts toward superior PEFC is also discussed. Carbon 93-99 zinc finger protein 135 Homo sapiens 86-89 31649781-4 2019 We report the first case of a girl with a genetically identified mutation in NKX2-1 that presents with a Chiari Malformation Type 1, eventually expanding the phenotypic spectrum of NKX2-1-related disorders while also highlighting a novel heterozygous pathogenic variant at exon 3 that disrupts the reading framework, originating an NKX2-1 protein with a different C-terminal. Carbon 105-106 NK2 homeobox 1 Homo sapiens 77-83 31649781-4 2019 We report the first case of a girl with a genetically identified mutation in NKX2-1 that presents with a Chiari Malformation Type 1, eventually expanding the phenotypic spectrum of NKX2-1-related disorders while also highlighting a novel heterozygous pathogenic variant at exon 3 that disrupts the reading framework, originating an NKX2-1 protein with a different C-terminal. Carbon 105-106 NK2 homeobox 1 Homo sapiens 181-187 31649781-4 2019 We report the first case of a girl with a genetically identified mutation in NKX2-1 that presents with a Chiari Malformation Type 1, eventually expanding the phenotypic spectrum of NKX2-1-related disorders while also highlighting a novel heterozygous pathogenic variant at exon 3 that disrupts the reading framework, originating an NKX2-1 protein with a different C-terminal. Carbon 105-106 NK2 homeobox 1 Homo sapiens 181-187 31274439-7 2019 The SXR curve of the contaminated mirror shows a clear dip near the critical momentum transfer of carbon, indicating the presence of carbon contamination on the mirror surface. Carbon 133-139 nuclear receptor subfamily 1 group I member 2 Homo sapiens 4-7 31050110-2 2019 Herein, we report for the first time of a new yolk-shell structured high tap density composite made of a carbon-coated rigid SiO2 outer shell to confine multiple Si NPs (yolks) and carbon nanotubes (CNTs) with embedded Fe2 O3 nanoparticles (NPs). Carbon 105-111 SEC14 like lipid binding 2 Homo sapiens 73-76 30952235-9 2019 Up to 500 mg of sample were efficiently digested by the proposed method in 5 min (dissolved carbon in digests was below 50 mg L-1). Carbon 92-98 immunoglobulin kappa variable 1-16 Homo sapiens 126-129 31050110-2 2019 Herein, we report for the first time of a new yolk-shell structured high tap density composite made of a carbon-coated rigid SiO2 outer shell to confine multiple Si NPs (yolks) and carbon nanotubes (CNTs) with embedded Fe2 O3 nanoparticles (NPs). Carbon 181-187 SEC14 like lipid binding 2 Homo sapiens 73-76 30954023-8 2019 We show that cells treated with Poly I:C induced IFN-beta secretion but not cells treated with LPS. Carbon 39-40 IFN1@ Homo sapiens 49-57 32373781-0 2019 Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells. Carbon 40-47 CD4 molecule Homo sapiens 118-121 30964644-1 2019 Organocobalt(III) complexes (R-CoIII), defined as cobalt complexes featuring a carbon-cobalt bond, are largely used to produce carbon-centered radicals by homolytic cleavage of their C-Co bond under mild conditions. Carbon 79-85 mitochondrially encoded cytochrome c oxidase III Homo sapiens 31-36 30964644-1 2019 Organocobalt(III) complexes (R-CoIII), defined as cobalt complexes featuring a carbon-cobalt bond, are largely used to produce carbon-centered radicals by homolytic cleavage of their C-Co bond under mild conditions. Carbon 127-133 mitochondrially encoded cytochrome c oxidase III Homo sapiens 31-36 31004379-2 2019 Mechanistic investigations, including kinetic studies, studies of the effect of temperature, solvent, and the para substituent of the aryl group, as well as DFT calculations, suggest that the C(sp2 )-CF3 reductive elimination proceeds through a concerted carbon-carbon bond-forming pathway. Carbon 255-261 Sp2 transcription factor Homo sapiens 192-197 31460146-3 2019 Here, we report a computational study on the mechanisms of the cytotoxicity of carbon nanotubes (CNTs) by investigating the direct impacts of CNTs on the functional motions of calmodulin (CaM), which is one of the most important signaling proteins in a cell, and its signaling function relies on the Ca2+ binding-coupled conformational switching. Carbon 79-85 calmodulin 1 Homo sapiens 176-186 31460146-3 2019 Here, we report a computational study on the mechanisms of the cytotoxicity of carbon nanotubes (CNTs) by investigating the direct impacts of CNTs on the functional motions of calmodulin (CaM), which is one of the most important signaling proteins in a cell, and its signaling function relies on the Ca2+ binding-coupled conformational switching. Carbon 79-85 calmodulin 1 Homo sapiens 188-191 31155631-0 2019 High bond difference parameter-induced low thermal transmission in carbon allotropes with sp2 and sp3 hybridization. Carbon 67-73 Sp2 transcription factor Homo sapiens 90-93 31155631-0 2019 High bond difference parameter-induced low thermal transmission in carbon allotropes with sp2 and sp3 hybridization. Carbon 67-73 Sp3 transcription factor Homo sapiens 98-101 31155631-2 2019 In this work, thermal transmission in three novel carbon allotropes with sp2 and sp3 hybridization has been studied, including T6-carbon, T10 and 3D-C5 by using non-equilibrium molecular dynamic simulations and phonon kinetic theory. Carbon 50-56 Sp2 transcription factor Homo sapiens 73-76 31155631-2 2019 In this work, thermal transmission in three novel carbon allotropes with sp2 and sp3 hybridization has been studied, including T6-carbon, T10 and 3D-C5 by using non-equilibrium molecular dynamic simulations and phonon kinetic theory. Carbon 50-56 Sp3 transcription factor Homo sapiens 81-84 31004379-2 2019 Mechanistic investigations, including kinetic studies, studies of the effect of temperature, solvent, and the para substituent of the aryl group, as well as DFT calculations, suggest that the C(sp2 )-CF3 reductive elimination proceeds through a concerted carbon-carbon bond-forming pathway. Carbon 262-268 Sp2 transcription factor Homo sapiens 192-197 30927596-5 2019 Rh0, Ru0 and Pd0 nanoparticles on activated carbon provide a turnover frequency value of 188 min-1, 235 min-1 and 40 min-1, respectively, at 25.0 +- 0.1 C. They preserve their activity even after multiple use in H2 generation from the hydrolysis of ammonia borane. Carbon 44-50 CD59 molecule (CD59 blood group) Homo sapiens 104-122 31465019-0 2019 Correction to "Nitrogen-Doped Nanoporous Carbon Nanospheroids for Selective Dye Adsorption and Pb(II) Ion Removal from Waste Water". Carbon 41-47 submaxillary gland androgen regulated protein 3B Homo sapiens 95-101 31181802-8 2019 Modelling of 13C metabolite flux within both cell lines revealed decreased carbon flux from glucose in the TCA cycle in snai1-overexpressing Panc1 cells only. Carbon 75-81 snail family transcriptional repressor 1 Homo sapiens 120-125 31082208-1 2019 Here we report the surprising discovery that high-energy vinyl carbocations can be generated under strongly basic conditions, and that they engage in intramolecular sp3 C-H insertion reactions through the catalysis of weakly coordinating anion salts. Carbon 169-170 Sp3 transcription factor Homo sapiens 165-168 30986778-7 2019 For 100 nm carbon target, good agreement between experimental, TRAX and Geant4 simulation results can be observed. Carbon 11-17 translin associated factor X Homo sapiens 63-67 31134256-0 2019 Catalytic oxidation and reduction reactions of hydrophilic carbon clusters with NADH and cytochrome C: features of an electron transport nanozyme. Carbon 59-65 cytochrome c, somatic Homo sapiens 89-101 31115430-0 2019 Development of a carbon-11 PET radiotracer for imaging TRPC5 in the brain. Carbon 17-23 transient receptor potential cation channel subfamily C member 5 Homo sapiens 55-60 30969449-3 2019 Tetracoordinated carbon therein surprisingly employs orbitals that are more similar to sp2 than to sp3 hybrids in sigma bonds with adjacent ring atoms. Carbon 17-23 Sp2 transcription factor Homo sapiens 87-90 31183402-2 2019 We estimate these responses corresponded to 0.61 (0.45 to 0.79) PgC year-1 more North American carbon uptake during El Nino than during La Nina between 2007 and 2015, partially offsetting increases of net tropical biosphere-to-atmosphere carbon flux around El Nino. Carbon 95-101 progastricsin Homo sapiens 64-67 30969449-3 2019 Tetracoordinated carbon therein surprisingly employs orbitals that are more similar to sp2 than to sp3 hybrids in sigma bonds with adjacent ring atoms. Carbon 17-23 Sp3 transcription factor Homo sapiens 99-102 31183402-2 2019 We estimate these responses corresponded to 0.61 (0.45 to 0.79) PgC year-1 more North American carbon uptake during El Nino than during La Nina between 2007 and 2015, partially offsetting increases of net tropical biosphere-to-atmosphere carbon flux around El Nino. Carbon 238-244 progastricsin Homo sapiens 64-67 30810280-5 2019 We find that these animals exhibit a delayed age-related decline in protein turnover rates, as well as decreased steady-state neuronal glucose-6-phosphate levels and elevated carbon flux into the pentose phosphate pathway due to the induction of glucose-6-phosphate dehydrogenase (G6PD). Carbon 175-181 Zwischenferment Drosophila melanogaster 246-279 30879672-5 2019 Additionally, the activated carbon microspheres functionalized with acrylic acid showed improved adsorption capacities for Pb(II) ion (273.4 mg/g) and methylene blue (701.3 mg/g). Carbon 28-34 submaxillary gland androgen regulated protein 3B Homo sapiens 123-129 30985032-3 2019 Hard carbon aerogels show great advantages in mechanical strength and structural stability due to the sp3 -C-induced turbostratic "house-of-cards" structure. Carbon 5-11 Sp3 transcription factor Homo sapiens 102-105 30953872-3 2019 Under the optimized electrocatalytic conditions, the nickel complex immobilized glassy carbon electrodes (GCEs) displayed high sensitivity (0.663, 1.280, 1.990 and 0.182 muA/muM) towards glucose detection, which is much higher than that of 3D porous nickel networks. Carbon 87-93 latexin Homo sapiens 174-177 30901650-6 2019 In food simulants, C10-congener groups were predominant in SCCP carbon homologues and Cl6-and Cl7-congener groups were predominant in chlorine homologues. Carbon 64-70 homeobox C10 Homo sapiens 19-22 30952013-0 2019 Bimetallic ZrHf-based metal-organic framework embedded with carbon dots: Ultra-sensitive platform for early diagnosis of HER2 and HER2-overexpressed living cancer cells. Carbon 60-66 erb-b2 receptor tyrosine kinase 2 Homo sapiens 121-125 30952013-0 2019 Bimetallic ZrHf-based metal-organic framework embedded with carbon dots: Ultra-sensitive platform for early diagnosis of HER2 and HER2-overexpressed living cancer cells. Carbon 60-66 erb-b2 receptor tyrosine kinase 2 Homo sapiens 130-134 30988370-5 2019 Herein the systematic removal of carbons from either the hydroxy fatty acid or fatty acid regions of the most studied FAHFA, palmitic acid ester of 9-hydroxystearic acid (9-PAHSA), was achieved and these synthetic, abridged analogs were tested for their ability to attenuate IL-6 production. Carbon 33-40 interleukin 6 Homo sapiens 275-279 31209804-8 2019 In contrast, Pam3Cys and Poly(I:C), the agonist of TLR1/2 or TLR3, partly inhibited FI-RSV-enhanced lung inflammation. Carbon 32-34 toll like receptor 1 Homo sapiens 51-57 30889674-0 2019 Using Ca-doped carbon dots as catalyst to amplify signal to determine ultratrace thrombin by free-label aptamer-SERS method. Carbon 15-21 coagulation factor II, thrombin Homo sapiens 81-89 30744795-4 2019 For the same 20 V resting voltage, the content of carbon element remains unchanged in a broad range of working voltages: 40-150 V. X-ray photoelectron analysis further revealed that the sp2/sp3 and C-O/C O ratios increased significantly as the working voltage increased. Carbon 50-56 Sp2 transcription factor Homo sapiens 186-201 31072431-0 2019 Ovalbumin as a Precursor for Green Synthesis of Highly Fluorescent Carbon Dots for Cell Imaging. Carbon 67-73 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 0-9 31072431-1 2019 One-pot green synthesis of highly fluorescent carbon dots (CDs) was developed by hydrothermal treatments of ovalbumin (OVA) from hen eggs. Carbon 46-52 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 108-117 30989744-4 2019 These Ni(II)/phenanthroline-mediated coupling reactions can be performed with a variety of carbon substituents R1 and R2 (sp3 , sp2 , or aromatic), some of them functionalized. Carbon 91-97 Sp3 transcription factor Homo sapiens 122-125 30989744-4 2019 These Ni(II)/phenanthroline-mediated coupling reactions can be performed with a variety of carbon substituents R1 and R2 (sp3 , sp2 , or aromatic), some of them functionalized. Carbon 91-97 Sp2 transcription factor Homo sapiens 128-131 30808730-6 2019 Profiling of the metabolome demonstrates that suppression of CPS1 potentiates the effects of EGFR inhibition on central carbon metabolism, pyrimidine biosynthesis, and arginine metabolism, coinciding with reduced glycolysis and mitochondrial respiration. Carbon 120-126 epidermal growth factor receptor Homo sapiens 93-97 30897545-0 2019 Activation of ferrate by carbon nanotube for enhanced degradation of bromophenols: Kinetics, products, and involvement of Fe(V)/Fe(IV). Carbon 25-31 FEV transcription factor, ETS family member Homo sapiens 122-127 32789186-2 2019 This opportunity is particularly intriguing in semiconducting single-walled carbon nanotubes, in which covalently bonding organic functional groups to the sp 2 carbon lattice can produce tunable sp 3 quantum defects that fluoresce brightly in the shortwave IR, emitting pure single photons at room temperature. Carbon 76-82 Sp2 transcription factor Homo sapiens 155-159 32789186-2 2019 This opportunity is particularly intriguing in semiconducting single-walled carbon nanotubes, in which covalently bonding organic functional groups to the sp 2 carbon lattice can produce tunable sp 3 quantum defects that fluoresce brightly in the shortwave IR, emitting pure single photons at room temperature. Carbon 76-82 Sp3 transcription factor Homo sapiens 195-199 32789186-2 2019 This opportunity is particularly intriguing in semiconducting single-walled carbon nanotubes, in which covalently bonding organic functional groups to the sp 2 carbon lattice can produce tunable sp 3 quantum defects that fluoresce brightly in the shortwave IR, emitting pure single photons at room temperature. Carbon 160-166 Sp2 transcription factor Homo sapiens 155-159 32789186-2 2019 This opportunity is particularly intriguing in semiconducting single-walled carbon nanotubes, in which covalently bonding organic functional groups to the sp 2 carbon lattice can produce tunable sp 3 quantum defects that fluoresce brightly in the shortwave IR, emitting pure single photons at room temperature. Carbon 160-166 Sp3 transcription factor Homo sapiens 195-199 31411588-0 2019 Study of impact of acids and comparison of adsorption efficiency of Pb(II) from carbon and its modified nano-nickel coated version. Carbon 80-86 submaxillary gland androgen regulated protein 3B Homo sapiens 68-74 31050437-4 2019 A single carbon insertion in the aliphatic chain of DA gives rise to the significantly accelerated intermolecular assembly and surface coating of CPA. Carbon 9-15 carboxypeptidase A1 Homo sapiens 146-149 31411588-2 2019 Nano-nickel coated carbon (Ni/C), compared with uncoated carbon (C), has shown a much enhanced (almost 80% higher) tendency of Pb(II) removal from solutions having different acid concentrations. Carbon 19-25 submaxillary gland androgen regulated protein 3B Homo sapiens 127-133 31411588-2 2019 Nano-nickel coated carbon (Ni/C), compared with uncoated carbon (C), has shown a much enhanced (almost 80% higher) tendency of Pb(II) removal from solutions having different acid concentrations. Carbon 57-63 submaxillary gland androgen regulated protein 3B Homo sapiens 127-133 30947043-1 2019 Response Surface Methodology (RSM) was used to investigate how the crude glycerin concentration and the carbon to nitrogen (C:N) ratio in the culture medium affect four indicators of polyhydroxyalkanoates (PHAs) accumulation by mixed microbial cultures (MMC): the observed coefficient of active-biomass yield (Yobs,BA), the observed coefficient of PHA yield (Yobs,PHA), the PHA content in biomass (XPHA) and the volumetric productivity (PrV). Carbon 104-110 lamin B receptor Homo sapiens 206-209 30947043-5 2019 The optimal conditions for PHA accumulation were a crude glycerin concentration of 8954 mg COD/L with a C:N ratio of 15.9 mg C/mg N-NH4, which gave a Yobs,BA of 0.29 mg CODBA/mg COD, a Yobs,PHA of 0.28 mg CODPHA/mg COD, a XPHA of 55.6% VSS and a PrV of 757.3 mg CODPHA/L d (550.0 mg PHA/L d). Carbon 91-92 lamin B receptor Homo sapiens 27-30 31159328-7 2019 The shrinking Eopt can be attributed to the fact that boron atoms act as a fluxing agent to promote carbon atoms to form sp2 hybridization at low energy. Carbon 100-106 Sp2 transcription factor Homo sapiens 121-124 31159328-8 2019 Furthermore, boron atoms can impede the formation of sigma bonds in carbon atom sp3 hybridization by forming B-C bonds with high energy, and induce the sp3 hybridization transfer to sp2 hybridization. Carbon 68-74 Sp3 transcription factor Homo sapiens 80-83 31159328-8 2019 Furthermore, boron atoms can impede the formation of sigma bonds in carbon atom sp3 hybridization by forming B-C bonds with high energy, and induce the sp3 hybridization transfer to sp2 hybridization. Carbon 68-74 Sp2 transcription factor Homo sapiens 182-185 31094397-5 2019 Two types of carbon films, one rich in graphite-like nitrogen-containing bonds and the other rich in pyridine-like bonds, were successfully fabricated without changing their nitrogen concentration, sp2/sp3 ratio or surface flatness. Carbon 13-19 Sp2 transcription factor Homo sapiens 198-201 31094397-5 2019 Two types of carbon films, one rich in graphite-like nitrogen-containing bonds and the other rich in pyridine-like bonds, were successfully fabricated without changing their nitrogen concentration, sp2/sp3 ratio or surface flatness. Carbon 13-19 Sp3 transcription factor Homo sapiens 202-205 30768269-4 2019 The early response of CL-20/TNT to thermal stimulus is dominated by N-NO2 bond cleavage for NO2 formation and C-N bond scission leading to ring-opening of CL-20. Carbon 22-23 epithelial membrane protein 1 Homo sapiens 155-160 30768269-5 2019 The kinetics of N-NO2 and C-N bond cleavage, as well as the following oxygen-abstraction of NO2, are significantly slowed in the CL-20/TNT thermolysis against beta-CL-20, which are responsible for the low sensitivity at the stage of active intermediate generation. Carbon 26-27 epithelial membrane protein 1 Homo sapiens 129-134 30768269-5 2019 The kinetics of N-NO2 and C-N bond cleavage, as well as the following oxygen-abstraction of NO2, are significantly slowed in the CL-20/TNT thermolysis against beta-CL-20, which are responsible for the low sensitivity at the stage of active intermediate generation. Carbon 26-27 epithelial membrane protein 1 Homo sapiens 164-169 31139936-7 2019 Graphical abstract Schematic presentation for the synthesis of Cr-CDs (chromium(III)-doped carbon dots) and their application to the fluorometric determination of p-NP (p-nitrophenol) based on an inner filter effect. Carbon 91-97 purine nucleoside phosphorylase Homo sapiens 163-167 31109034-0 2019 Carbon Dot-Mediated Capillary Electrophoresis Separations of Metallated and Demetallated Forms of Transferrin Protein. Carbon 0-6 transferrin Homo sapiens 98-109 31123133-1 2019 The opening of epoxides typically requires electrophilic activation, and subsequent nucleophilic (SN2) attack on the less substituted carbon leads to alcohols with Markovnikov regioselectivity. Carbon 134-140 solute carrier family 38 member 5 Homo sapiens 98-101 30916964-2 2019 We find that the most favorable interactions are found between the carbon in CO2 and the main heterocycle in the ring in a parallel orientation, whereas the preferred interaction mode of CS2 is established between sulfur and the pi density of the aromatic ring. Carbon 67-73 chorionic somatomammotropin hormone 2 Homo sapiens 187-190 31042378-0 2019 Comment on "A Pilot-Scale Field Study: In Situ Treatment of PCB-Impacted Sediments with Bioamended Activated Carbon". Carbon 109-116 pyruvate carboxylase Homo sapiens 60-63 31137814-5 2019 When the position of cinnamic acid moiety was placed at 4" carbon of aniline ring, PPARgamma agonist activity was completely abolished. Carbon 59-65 peroxisome proliferator activated receptor gamma Homo sapiens 83-92 31122262-12 2019 CONCLUSION: This study demonstrated a nonlinear relationship between IGF-1 and LDL-C independent of other potential confounding factors, suggesting that circulating IGF-1 may contribute to the regulation of LDL-C levels, thus meriting further investigation. Carbon 82-84 insulin like growth factor 1 Homo sapiens 69-74 31122262-12 2019 CONCLUSION: This study demonstrated a nonlinear relationship between IGF-1 and LDL-C independent of other potential confounding factors, suggesting that circulating IGF-1 may contribute to the regulation of LDL-C levels, thus meriting further investigation. Carbon 82-84 insulin like growth factor 1 Homo sapiens 165-170 31122262-12 2019 CONCLUSION: This study demonstrated a nonlinear relationship between IGF-1 and LDL-C independent of other potential confounding factors, suggesting that circulating IGF-1 may contribute to the regulation of LDL-C levels, thus meriting further investigation. Carbon 210-212 insulin like growth factor 1 Homo sapiens 69-74 31122262-12 2019 CONCLUSION: This study demonstrated a nonlinear relationship between IGF-1 and LDL-C independent of other potential confounding factors, suggesting that circulating IGF-1 may contribute to the regulation of LDL-C levels, thus meriting further investigation. Carbon 210-212 insulin like growth factor 1 Homo sapiens 165-170 31281489-3 2019 Methods: In this work, we have successfully synthesized mesoporous carbon-gold hybrid nanozyme nanoprobes, whereby mesoporous carbon nanospheres were doped with small gold nanoparticles (OMCAPs) and further stabilized with a complex of reduced serum albumin and folic acid (rBSA-FA). Carbon 67-73 albumin Homo sapiens 250-257 31038939-2 2019 Granular activated carbon (GAC) adsorption is well-established for controlling regulated disinfection byproducts (DBPs), but its effectiveness for unregulated DBPs and DBP-associated toxicity is unclear. Carbon 19-25 D-box binding PAR bZIP transcription factor Homo sapiens 114-117 31172013-4 2019 Here, we show that carbon source, an essential nutrient, impacts Rnr1 and Rnr3 abundance: Non-fermentable carbon sources or limiting concentrations of glucose down regulate Rnr1 and induce Rnr3 expression. Carbon 19-25 ribonucleotide-diphosphate reductase subunit RNR3 Saccharomyces cerevisiae S288C 74-78 31172013-4 2019 Here, we show that carbon source, an essential nutrient, impacts Rnr1 and Rnr3 abundance: Non-fermentable carbon sources or limiting concentrations of glucose down regulate Rnr1 and induce Rnr3 expression. Carbon 19-25 ribonucleotide-diphosphate reductase subunit RNR3 Saccharomyces cerevisiae S288C 189-193 31172013-4 2019 Here, we show that carbon source, an essential nutrient, impacts Rnr1 and Rnr3 abundance: Non-fermentable carbon sources or limiting concentrations of glucose down regulate Rnr1 and induce Rnr3 expression. Carbon 106-112 ribonucleotide-diphosphate reductase subunit RNR3 Saccharomyces cerevisiae S288C 74-78 31172013-6 2019 The carbon source dependent regulation of Rnr3 is mediated by Mec1, the budding yeast ATM/ATR checkpoint response kinase. Carbon 4-10 ribonucleotide-diphosphate reductase subunit RNR3 Saccharomyces cerevisiae S288C 42-46 31172013-9 2019 Together, these results unveil involvement of Rnr3 in mitochondrial functions and Mec1 in mediating the carbon source dependent regulation of Rnr3. Carbon 104-110 ribonucleotide-diphosphate reductase subunit RNR3 Saccharomyces cerevisiae S288C 46-50 31172013-9 2019 Together, these results unveil involvement of Rnr3 in mitochondrial functions and Mec1 in mediating the carbon source dependent regulation of Rnr3. Carbon 104-110 ribonucleotide-diphosphate reductase subunit RNR3 Saccharomyces cerevisiae S288C 142-146 31096655-8 2019 In contrast, myo-inositol, had significantly lower concentrations in leaf samples despite up regulation of INPS suggesting the transcriptionally regulated flux of carbon through the myo-inositol pool is important during water deficit. Carbon 163-169 myo-inositol-3-phosphate synthase Glycine max 107-111 31038963-1 2019 The discovery of fullerenes, nanotubes, and graphene has ignited tremendous interest in exploring additional all-sp2 carbon networks with novel properties. Carbon 117-123 Sp2 transcription factor Homo sapiens 113-116 31038963-2 2019 Here we identify by ab initio calculations a new series of three-dimensional crystalline modification of carbon in all-sp2 bonding networks that comprise trigonal polycyclic benzenoid nanoflakes in a 2 n2 ( n >= 4) atom hexagonal cell. Carbon 105-111 Sp2 transcription factor Homo sapiens 119-122 31038963-5 2019 The present findings establish an additional crystalline modification of graphene in the all-sp2 carbon allotrope family and offer insights into its outstanding structural and electronic properties. Carbon 97-103 Sp2 transcription factor Homo sapiens 93-96 30480369-1 2019 Unlike extensively studied diradicals linked by pi-conjugated systems, only a few studies have investigated weakly coupled diradicals linked by an sp3 carbon atom. Carbon 151-157 Sp3 transcription factor Homo sapiens 147-150 30480369-4 2019 From these results and theoretical calculations of related diradicals, the spin-polarization model counting the small spin density of the sp3 carbon atom could be used as a spin-prediction model. Carbon 142-148 Sp3 transcription factor Homo sapiens 138-141 31101893-2 2019 Previous studies attributed the ultrahigh strength of the compressed glassy carbon to structural transformation from graphite-like sp2-bonded structure to diamond-like sp3-bonded structure. Carbon 76-82 Sp2 transcription factor Homo sapiens 131-134 31101893-2 2019 Previous studies attributed the ultrahigh strength of the compressed glassy carbon to structural transformation from graphite-like sp2-bonded structure to diamond-like sp3-bonded structure. Carbon 76-82 Sp3 transcription factor Homo sapiens 168-171 31101893-5 2019 Our results show that the C-C-C bond angle in the glassy carbon remains close to 120 , which is the ideal angle for the sp2-bonded honey-comb structure, up to 49.0 GPa. Carbon 26-27 Sp2 transcription factor Homo sapiens 120-123 31101893-5 2019 Our results show that the C-C-C bond angle in the glassy carbon remains close to 120 , which is the ideal angle for the sp2-bonded honey-comb structure, up to 49.0 GPa. Carbon 28-29 Sp2 transcription factor Homo sapiens 120-123 31101893-5 2019 Our results show that the C-C-C bond angle in the glassy carbon remains close to 120 , which is the ideal angle for the sp2-bonded honey-comb structure, up to 49.0 GPa. Carbon 28-29 Sp2 transcription factor Homo sapiens 120-123 31101893-5 2019 Our results show that the C-C-C bond angle in the glassy carbon remains close to 120 , which is the ideal angle for the sp2-bonded honey-comb structure, up to 49.0 GPa. Carbon 57-63 Sp2 transcription factor Homo sapiens 120-123 32952765-3 2019 In solution, the flexibility of the sp3-hybridized carbon atom in DMAC of DMAC-TPA-TRZ, compared to the rigid PXZ, allows significant conformational reorganization, giving rise to multiple charge-transfer excited states. Carbon 51-57 Sp3 transcription factor Homo sapiens 36-39 31360416-1 2019 We describe a powerful, broadly applicable cross-coupling protocol that enables carbon-carbon bond formation at highly sterically hindered carbon centers (both sp2 and sp3) by employing organocopper reagents under palladium catalysis. Carbon 80-86 Sp2 transcription factor Homo sapiens 160-163 31020285-2 2019 In the presence of 1 mol% NHC, various thiols underwent the sulfa-Michael-Michael cascade reaction with benzenedi(enones) efficiently to form the carbon-sulfur bond and construct sulfenylated indanes in good to excellent yields with high diastereoselectivity. Carbon 146-152 high mobility group nucleosomal binding domain 4 Homo sapiens 26-29 31360416-1 2019 We describe a powerful, broadly applicable cross-coupling protocol that enables carbon-carbon bond formation at highly sterically hindered carbon centers (both sp2 and sp3) by employing organocopper reagents under palladium catalysis. Carbon 80-86 Sp3 transcription factor Homo sapiens 168-171 31360416-1 2019 We describe a powerful, broadly applicable cross-coupling protocol that enables carbon-carbon bond formation at highly sterically hindered carbon centers (both sp2 and sp3) by employing organocopper reagents under palladium catalysis. Carbon 87-93 Sp2 transcription factor Homo sapiens 160-163 31360416-1 2019 We describe a powerful, broadly applicable cross-coupling protocol that enables carbon-carbon bond formation at highly sterically hindered carbon centers (both sp2 and sp3) by employing organocopper reagents under palladium catalysis. Carbon 87-93 Sp3 transcription factor Homo sapiens 168-171 30793730-6 2019 Among the adsorbed proteins from FBS, apolipoprotein E, but not apolipoprotein A1, affected the cellular uptake of the carbon 14 LNPs. Carbon 119-125 apolipoprotein E Homo sapiens 38-54 31360416-1 2019 We describe a powerful, broadly applicable cross-coupling protocol that enables carbon-carbon bond formation at highly sterically hindered carbon centers (both sp2 and sp3) by employing organocopper reagents under palladium catalysis. Carbon 87-93 Sp2 transcription factor Homo sapiens 160-163 31360416-1 2019 We describe a powerful, broadly applicable cross-coupling protocol that enables carbon-carbon bond formation at highly sterically hindered carbon centers (both sp2 and sp3) by employing organocopper reagents under palladium catalysis. Carbon 87-93 Sp3 transcription factor Homo sapiens 168-171 31009570-3 2019 Herein, a Li2S@C nanocomposite with Li2S nanocrystals uniformly embedded in conductive carbon matrix, is in situ generated by the combustion of lithium metal with CS2. Carbon 87-93 chorionic somatomammotropin hormone 2 Homo sapiens 163-166 31011718-1 2019 An efficient protocol for the introduction of acetoxy and hydroxy functionalities on unactivated aryl sp2 carbons of oxobenzoxazine derivatives via an ortho-C-H activation reaction using a palladium catalyst has been developed for the first time. Carbon 106-113 Sp2 transcription factor Homo sapiens 102-105 31058221-3 2019 With oxidase catalysis as a model reaction, experimental studies and theoretical calculations revealed that single-atom nanozymes with carbon nanoframe-confined FeN5 active centers (FeN5 SA/CNF) catalytically behaved like the axial ligand-coordinated heme of cytochrome P450. Carbon 135-141 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 259-274 30900781-0 2019 Fully sp2 -Carbon-Linked Crystalline Two-Dimensional Conjugated Polymers: Insight into 2D Poly(phenylenecyanovinylene) Formation and its Optoelectronic Properties. Carbon 11-17 Sp2 transcription factor Homo sapiens 6-9 30900781-3 2019 In this work, we present the efficient synthesis of two novel 2D fully sp2 -carbon-linked crystalline PPVs and investigate the essentiality of inorganic bases for their catalytic formation. Carbon 76-82 Sp2 transcription factor Homo sapiens 71-74 30835963-2 2019 A variety of structurally diverse sp3 - and sp-hybridized carbon nucleophiles, including esters, amides, fluorenes, terminal alkynes, beta-ketoesters, malonates, and other activated C-H nucleophiles, could be efficiently and selectively transformed into the corresponding C-difluoromethylated products under mild conditions. Carbon 58-64 Sp3 transcription factor Homo sapiens 34-37 30843633-3 2019 Gram-scale quantities of these curved nanographenes (TCR and HCR) as the "crown" sidewalls can be incorporated into a carbon nanoring to form molecular crowns, and the molecular structure of C60 @TCR is determined by single-crystal X-ray diffraction. Carbon 118-124 C-C motif chemokine receptor like 2 Homo sapiens 61-64 30884054-0 2019 Designed Synthesis of a 2D Porphyrin-Based sp2 Carbon-Conjugated Covalent Organic Framework for Heterogeneous Photocatalysis. Carbon 47-53 Sp2 transcription factor Homo sapiens 43-46 30884054-3 2019 Owing to the C=C linkages, Por-sp2 c-COF shows a high chemical stability under various conditions, even under harsh conditions such as 9 m HCl and 9 m NaOH solutions. Carbon 13-14 Sp2 transcription factor Homo sapiens 31-34 30884054-3 2019 Owing to the C=C linkages, Por-sp2 c-COF shows a high chemical stability under various conditions, even under harsh conditions such as 9 m HCl and 9 m NaOH solutions. Carbon 15-16 Sp2 transcription factor Homo sapiens 31-34 30884054-6 2019 This clearly demonstrates that sp2 carbon-linked 2D COFs can provide an interesting platform for heterogeneous photocatalysis. Carbon 35-41 Sp2 transcription factor Homo sapiens 31-34 30905713-9 2019 We now report that TDP-43 is much more toxic when yeast are respiring than when grown on a carbon source where respiration is inhibited. Carbon 91-97 TAR DNA binding protein Homo sapiens 19-25 31459894-4 2019 The C-C bond formation through sp3-CH functionalization involves a wide scope of the substrates, high atom efficiency, chemoselectivity, and environmentally friendly strategy. Carbon 6-7 Sp3 transcription factor Homo sapiens 31-34 30951295-1 2019 Carbon nanothreads are a new one-dimensional sp3-bonded nanomaterial of CH stoichiometry synthesized from benzene at high pressure and room temperature by slow solid-state polymerization. Carbon 0-6 Sp3 transcription factor Homo sapiens 45-48 31133774-2 2019 One gene associated with increased risk for ASD is methylenetetrahydrofolate-reductase (MTHFR), which encodes a key enzyme in one carbon (C1) metabolism. Carbon 130-136 methylenetetrahydrofolate reductase Mus musculus 51-86 31133774-2 2019 One gene associated with increased risk for ASD is methylenetetrahydrofolate-reductase (MTHFR), which encodes a key enzyme in one carbon (C1) metabolism. Carbon 130-136 methylenetetrahydrofolate reductase Mus musculus 88-93 30919523-5 2019 C K-edge near edge X-ray absorption fine structure measurements and density functional theory calculations reveal that sp2 defects (octagonal and pentagonal) rather than edge defects are key to the excellent ECRR activity of the defective porous carbon catalysts. Carbon 246-252 Sp2 transcription factor Homo sapiens 119-122 30997850-1 2019 Aim: MTHFD1 was the enzyme providing one-carbon derivatives of tetrahydrofolate. Carbon 41-47 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 5-11 31018808-4 2019 Higher percentages of TLR2, TLR3, TLR4, and TLR7 were expressed on such lymphocytes, and the TLR agonists PGN, Poly I:C, LPS, and R848 induced a higher level of IFN-gamma. Carbon 118-119 interferon gamma Mus musculus 161-170 30983333-2 2019 In contrast, formal oxidative addition of copper to Csp2 carbon-bromine bonds can be accomplished by employing latent silyl radicals under photoredox conditions. Carbon 57-63 regulator of calcineurin 2 Homo sapiens 52-56 31459894-4 2019 The C-C bond formation through sp3-CH functionalization involves a wide scope of the substrates, high atom efficiency, chemoselectivity, and environmentally friendly strategy. Carbon 4-5 Sp3 transcription factor Homo sapiens 31-34 30965001-2 2019 MCM/V2O5 composites exhibit high dispersion of nanostructured V2O5 in a mesoporous carbon matrix, beneficial to fast reversible redox reactions with a short diffusion path. Carbon 83-89 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Homo sapiens 0-3 30828757-0 2019 Ratiometric fluorescent sensor for visual determination of copper ions and alkaline phosphatase based on carbon quantum dots and gold nanoclusters. Carbon 105-111 alkaline phosphatase, placental Homo sapiens 75-95 30856427-6 2019 Here we show that O2-reducing EABs can grow in unamended tap water on carbon electrodes at + 0.2 V vs. Ag/AgCl. Carbon 70-76 USO1 vesicle transport factor Homo sapiens 57-60 30856429-0 2019 Electrochemical immunosensors with AuPt-vertical graphene/glassy carbon electrode for alpha-fetoprotein detection based on label-free and sandwich-type strategies. Carbon 65-71 alpha fetoprotein Homo sapiens 86-103 30683380-3 2019 Among the carbon substrates tested, regular carbon screen-printed devices exhibited the best performance, with detection limits of 4.8 and 6.6 mumol L-1 and linearity ranges of 16-400 and 22-400 mumol L-1 for BP3 and OC, respectively, and, as compared to mercury electrodes, with the advantages of environmental safety, easy of use, low cost and compatibility with automation and flow measurements. Carbon 10-16 BP3 Homo sapiens 209-212 30957431-2 2019 Herein, a Co-engineered FeOOH catalyst integrated on carbon fiber paper (Co-FeOOH/CFP) is reported, which realized a great improvement of the oxygen evolution activity by tuning the coordination geometry of the Fe species with an electrochemically driven method. Carbon 53-59 complement factor properdin Homo sapiens 82-85 30387134-0 2019 Toll-like receptor 3 agonist poly I:C reinforces the potency of cytotoxic chemotherapy via the TLR3-UNC93B1-IFN-beta signaling axis in paclitaxel-resistant colon cancer. Carbon 36-37 unc-93 homolog B1, TLR signaling regulator Homo sapiens 100-107 30813070-1 2019 A novel sensor of a square wave anodic stripping voltammetric (SWASV) determination of Pb(II) and Cd(II) with a Multiwall carbon nanotube MWCNT/(H2bpabza) novel tetradentate carboxamide ligand modified electrode is reported. Carbon 122-128 submaxillary gland androgen regulated protein 3B Homo sapiens 87-93 30683380-3 2019 Among the carbon substrates tested, regular carbon screen-printed devices exhibited the best performance, with detection limits of 4.8 and 6.6 mumol L-1 and linearity ranges of 16-400 and 22-400 mumol L-1 for BP3 and OC, respectively, and, as compared to mercury electrodes, with the advantages of environmental safety, easy of use, low cost and compatibility with automation and flow measurements. Carbon 44-50 BP3 Homo sapiens 209-212 31015425-4 2019 The region"s aboveground forest carbon stock (AFCS) would decrease by 790 Tg C, 21% of which would be due to old-growth forest loss. Carbon 32-38 transglutaminase 2 Homo sapiens 74-78 30726997-4 2019 Within one-carbon metabolism, methylenetetrahydrofolate reductase (MTHFR) catalyzes the irreversible conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. Carbon 11-17 methylenetetrahydrofolate reductase Mus musculus 30-65 30726997-4 2019 Within one-carbon metabolism, methylenetetrahydrofolate reductase (MTHFR) catalyzes the irreversible conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. Carbon 11-17 methylenetetrahydrofolate reductase Mus musculus 67-72 31016555-7 2019 RESULTS: Results show that emissions from the agriculture sector in the BAU will increase from 45.3 MtCO2eq in 2015 to 63.6 MtCO2eq in 2050, whereas net emission from the AFOLU will be 8.3 MtCO2eq in 2015 and 24.6 MtCO2eq in 2050. Carbon 72-75 mitochondrially encoded cytochrome c oxidase II Homo sapiens 100-105 31016555-7 2019 RESULTS: Results show that emissions from the agriculture sector in the BAU will increase from 45.3 MtCO2eq in 2015 to 63.6 MtCO2eq in 2050, whereas net emission from the AFOLU will be 8.3 MtCO2eq in 2015 and 24.6 MtCO2eq in 2050. Carbon 72-75 mitochondrially encoded cytochrome c oxidase II Homo sapiens 124-129 30822598-6 2019 CBP further increased with increasing ozone dose due to production of more biodegradable carbon. Carbon 89-95 CREB binding protein Homo sapiens 0-3 30822598-7 2019 Growth promotion by carbon was confirmed from the consumption of ozonation byproducts (carboxylic acids, aldehydes) and the increase in CBP (9.5 x 102-2.9 x 103 d ngATP/L) after addition of 50-300 mugC/L acetate. Carbon 20-26 CREB binding protein Homo sapiens 136-139 31011151-10 2019 Moreover, Mx1 and its related proinflamatory genes (Mx2, Il1b, and Tnf) were also up-regulated in poly I:C-treated mice. Carbon 105-106 MX dynamin-like GTPase 2 Mus musculus 52-55 31011151-10 2019 Moreover, Mx1 and its related proinflamatory genes (Mx2, Il1b, and Tnf) were also up-regulated in poly I:C-treated mice. Carbon 105-106 interleukin 1 beta Mus musculus 57-61 31011151-10 2019 Moreover, Mx1 and its related proinflamatory genes (Mx2, Il1b, and Tnf) were also up-regulated in poly I:C-treated mice. Carbon 105-106 tumor necrosis factor Mus musculus 67-70 30995772-6 2019 In vitro incubation with bee venom PLA2 demonstrated that a 7-carbon linker between the PL and Fmoc has higher activation rate than a 5-carbon linker. Carbon 62-68 phospholipase A2 group IB Homo sapiens 35-39 31003551-0 2019 Novel Carbon/PEDOT/PSS-Based Screen-Printed Biosensors for Acetylcholine Neurotransmitter and Acetylcholinesterase Detection in Human Serum. Carbon 6-12 acetylcholinesterase (Cartwright blood group) Homo sapiens 59-114 30740789-1 2019 An ice/salt-assisted strategy has been developed to achieve the green and efficient synthesis of ultrathin two-dimensional (2D) micro/mesoporous carbon nanosheets (CNS) with the dominant active moieties of Fe-N4 (Fe-N-CNS) as high-performance electrocatalysts for the oxygen reduction reaction (ORR). Carbon 145-151 carboxylesterase 2 Homo sapiens 3-6 30768737-1 2019 Breaking the electroneutrality of sp2 carbon lattice is a viable way for nanocarbon material to modulate the charge delocalization and to further alter the electrocatalytic activity. Carbon 38-44 Sp2 transcription factor Homo sapiens 34-37 30995772-6 2019 In vitro incubation with bee venom PLA2 demonstrated that a 7-carbon linker between the PL and Fmoc has higher activation rate than a 5-carbon linker. Carbon 136-142 phospholipase A2 group IB Homo sapiens 35-39 30995772-9 2019 PL-methotrexate conjugate with 6-carbon linker showed the highest extent of PLA2-mediated activation, whereas shorter linkers were activated to a lower extent. Carbon 33-39 phospholipase A2 group IB Homo sapiens 76-80 30797108-2 2019 The electrochemical impedance spectroscopy (EIS) investigations surprisingly revealed that the glassy carbon electrode (GC) electrode modified with Chit-Naf composite had higher electron transfer kinetics compared the bare GC, GC/Naf and GC/Chit electrodes, which promises a great potential as an efficient platform in construction of biosensing assays. Carbon 102-108 C-X-C motif chemokine ligand 8 Homo sapiens 153-156 30797108-2 2019 The electrochemical impedance spectroscopy (EIS) investigations surprisingly revealed that the glassy carbon electrode (GC) electrode modified with Chit-Naf composite had higher electron transfer kinetics compared the bare GC, GC/Naf and GC/Chit electrodes, which promises a great potential as an efficient platform in construction of biosensing assays. Carbon 102-108 C-X-C motif chemokine ligand 8 Homo sapiens 230-233 30849722-0 2019 A ratiometric fluorescence probe based on carbon dots for discriminative and highly sensitive detection of acetylcholinesterase and butyrylcholinesterase in human whole blood. Carbon 42-48 acetylcholinesterase (Cartwright blood group) Homo sapiens 107-127 30849722-1 2019 A ratiometric fluorescence probe based on carbon dots (CDs) was developed for discriminative and highly sensitive detection of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activity in human whole blood. Carbon 42-48 acetylcholinesterase (Cartwright blood group) Homo sapiens 127-147 30849722-1 2019 A ratiometric fluorescence probe based on carbon dots (CDs) was developed for discriminative and highly sensitive detection of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activity in human whole blood. Carbon 42-48 acetylcholinesterase (Cartwright blood group) Homo sapiens 149-153 30735885-4 2019 When the mass percentage of the carbon foam was 10%, the CoOx/C composite (CoOx/C-10) exhibited a high specific capacity (115 mAh g-1 at 0.5 A g-1), an excellent rate capability (73 mAh g-1 at 10 A g-1) and a good cycling stability (86% after 6000 cycles at 1 A g-1). Carbon 32-38 homeobox C10 Homo sapiens 80-84 30860388-0 2019 Stereospecific Iron-Catalyzed Carbon(sp2)-Carbon(sp3) Cross-Coupling with Alkyllithium and Alkenyl Iodides. Carbon 30-36 Sp2 transcription factor Homo sapiens 37-40 30860388-0 2019 Stereospecific Iron-Catalyzed Carbon(sp2)-Carbon(sp3) Cross-Coupling with Alkyllithium and Alkenyl Iodides. Carbon 30-36 Sp3 transcription factor Homo sapiens 49-52 30924663-0 2019 Ni-catalyzed Reductive Deaminative Arylation at sp3 Carbon Centers. Carbon 52-58 Sp3 transcription factor Homo sapiens 48-51 30924663-1 2019 A Ni-catalyzed reductive deaminative arylation at unactivated sp3 carbon centers is described. Carbon 66-72 Sp3 transcription factor Homo sapiens 62-65 30708020-0 2019 Carbon dot festooned and surface passivated graphene-reinforced chitosan construct for tumor-targeted delivery of TNF-alpha gene. Carbon 0-6 tumor necrosis factor Homo sapiens 114-123 30708020-5 2019 The surface passivated carrier (PEG-pDNA-TNF-alpha-CS-CGO) then festooned with the folic acid derived carbon dots (C-dots) for targeting folate receptors that are overexpressed in most of the cancer cells. Carbon 102-108 tumor necrosis factor Homo sapiens 41-50 30735885-4 2019 When the mass percentage of the carbon foam was 10%, the CoOx/C composite (CoOx/C-10) exhibited a high specific capacity (115 mAh g-1 at 0.5 A g-1), an excellent rate capability (73 mAh g-1 at 10 A g-1) and a good cycling stability (86% after 6000 cycles at 1 A g-1). Carbon 57-58 homeobox C10 Homo sapiens 80-84 30991634-5 2019 Our studies have established that a low protein to carbohydrate (P:C) ratio can increase lifespan, motor ability and mitochondrial function in a parkin mutant Drosophila model of PD. Carbon 67-68 parkin Drosophila melanogaster 145-151 30851693-3 2019 For all the tacrine-tryptophan heterodimers, favorable inhibitory effect on hAChE as well as on hBChE was coined to the optimal spacer length ranging from five to eight carbon atoms between these two pharmacophores. Carbon 169-175 acetylcholinesterase (Cartwright blood group) Homo sapiens 76-81 31037071-6 2019 beta-Glucan, oS100A and tenascin C induced training of monocytes to release more TNFalpha. Carbon 33-34 tumor necrosis factor Homo sapiens 81-89 30969367-0 2019 Photoelectrochemical aptamer-based sensing of the vascular endothelial growth factor by adjusting the light harvesting efficiency of g-C3N4 via porous carbon spheres. Carbon 151-157 vascular endothelial growth factor A Homo sapiens 50-84 30989397-10 2019 Graphical abstract Schematic presentation of the synthesis of nitrogen and copper co-doped carbon dots (N,Cu-CDs) and their application as an enzyme mimic for colorimetric discrimination of ortho-, meta- and para-phenylenediamine (OPD, MPD and PPD). Carbon 91-97 mevalonate diphosphate decarboxylase Homo sapiens 236-239 30892009-2 2019 A systematic structural analysis of CNSs reveals that the thickness of polymer films affects the interaction between molecules and a Si wafer significantly, thus helping to determine the ratio of sp2 and sp3 bonding configurations of carbon (C) atoms in the CNS. Carbon 234-240 Sp2 transcription factor Homo sapiens 196-199 30892009-2 2019 A systematic structural analysis of CNSs reveals that the thickness of polymer films affects the interaction between molecules and a Si wafer significantly, thus helping to determine the ratio of sp2 and sp3 bonding configurations of carbon (C) atoms in the CNS. Carbon 234-240 Sp3 transcription factor Homo sapiens 204-207 30892009-3 2019 Notably, the holding time of carbonization can realize a hierarchical structure with graphitic carbon dots emerging from the CNS through the rearrangement of carbon atoms, leading to the excellent kappa value of 540 W/(m K) at 310 K. It is demonstrated that an appropriate increase in carbonization time can be an effective approach for improving the ratio of sp2- to sp3-bonded C atoms in the CNS. Carbon 29-35 Sp2 transcription factor Homo sapiens 360-363 30892009-3 2019 Notably, the holding time of carbonization can realize a hierarchical structure with graphitic carbon dots emerging from the CNS through the rearrangement of carbon atoms, leading to the excellent kappa value of 540 W/(m K) at 310 K. It is demonstrated that an appropriate increase in carbonization time can be an effective approach for improving the ratio of sp2- to sp3-bonded C atoms in the CNS. Carbon 29-35 Sp3 transcription factor Homo sapiens 368-371 30892009-3 2019 Notably, the holding time of carbonization can realize a hierarchical structure with graphitic carbon dots emerging from the CNS through the rearrangement of carbon atoms, leading to the excellent kappa value of 540 W/(m K) at 310 K. It is demonstrated that an appropriate increase in carbonization time can be an effective approach for improving the ratio of sp2- to sp3-bonded C atoms in the CNS. Carbon 95-101 Sp2 transcription factor Homo sapiens 360-363 30892009-3 2019 Notably, the holding time of carbonization can realize a hierarchical structure with graphitic carbon dots emerging from the CNS through the rearrangement of carbon atoms, leading to the excellent kappa value of 540 W/(m K) at 310 K. It is demonstrated that an appropriate increase in carbonization time can be an effective approach for improving the ratio of sp2- to sp3-bonded C atoms in the CNS. Carbon 95-101 Sp3 transcription factor Homo sapiens 368-371 30892009-3 2019 Notably, the holding time of carbonization can realize a hierarchical structure with graphitic carbon dots emerging from the CNS through the rearrangement of carbon atoms, leading to the excellent kappa value of 540 W/(m K) at 310 K. It is demonstrated that an appropriate increase in carbonization time can be an effective approach for improving the ratio of sp2- to sp3-bonded C atoms in the CNS. Carbon 125-126 Sp2 transcription factor Homo sapiens 360-363 30892009-3 2019 Notably, the holding time of carbonization can realize a hierarchical structure with graphitic carbon dots emerging from the CNS through the rearrangement of carbon atoms, leading to the excellent kappa value of 540 W/(m K) at 310 K. It is demonstrated that an appropriate increase in carbonization time can be an effective approach for improving the ratio of sp2- to sp3-bonded C atoms in the CNS. Carbon 125-126 Sp3 transcription factor Homo sapiens 368-371 30648614-10 2019 These data indicate that saturated fatty acids with different carbon chain length (C16:0, C20:0 and C26:0) have different effects on the process of Abeta generation, and fatty acids with longer chain (C20:0 and C26:0) have more potential to promote Abeta production and an underlying mechanism of fatty acids action may be related to the elevated oxidative stress. Carbon 62-68 amyloid beta precursor protein Homo sapiens 148-153 30730064-1 2019 Graphdiyne is a new carbon allotrope comprising sp- and sp2 -hybridized carbon atoms arranged in a 2D layered structure. Carbon 20-26 Sp2 transcription factor Homo sapiens 56-59 30761713-0 2019 Fully Conjugated Two-Dimensional sp2 -Carbon Covalent Organic Frameworks as Artificial Photosystem I with High Efficiency. Carbon 38-44 Sp2 transcription factor Homo sapiens 33-36 30761713-1 2019 The synthesis of fully conjugated sp2 -carbon covalent organic frameworks (COF) is extremely challenging given the difficulty of the formation of very stable carbon-carbon double bonds (-C=C-). Carbon 39-45 Sp2 transcription factor Homo sapiens 34-37 30761713-1 2019 The synthesis of fully conjugated sp2 -carbon covalent organic frameworks (COF) is extremely challenging given the difficulty of the formation of very stable carbon-carbon double bonds (-C=C-). Carbon 158-164 Sp2 transcription factor Homo sapiens 34-37 30761713-1 2019 The synthesis of fully conjugated sp2 -carbon covalent organic frameworks (COF) is extremely challenging given the difficulty of the formation of very stable carbon-carbon double bonds (-C=C-). Carbon 158-164 Sp2 transcription factor Homo sapiens 34-37 30761713-1 2019 The synthesis of fully conjugated sp2 -carbon covalent organic frameworks (COF) is extremely challenging given the difficulty of the formation of very stable carbon-carbon double bonds (-C=C-). Carbon 75-76 Sp2 transcription factor Homo sapiens 34-37 30761713-2 2019 Here, we report the successful preparation of a 2D COF (TP-COF) based on triazine as central planar units bridged by sp2 -carbon linkers through the -C=C- condensation reaction. Carbon 122-128 Sp2 transcription factor Homo sapiens 117-120 30761713-2 2019 Here, we report the successful preparation of a 2D COF (TP-COF) based on triazine as central planar units bridged by sp2 -carbon linkers through the -C=C- condensation reaction. Carbon 51-52 Sp2 transcription factor Homo sapiens 117-120 30761713-2 2019 Here, we report the successful preparation of a 2D COF (TP-COF) based on triazine as central planar units bridged by sp2 -carbon linkers through the -C=C- condensation reaction. Carbon 59-60 Sp2 transcription factor Homo sapiens 117-120 30594634-9 2019 This study demonstrated that maize ZmSnRK1 members play important roles in energy sensing and carbon metabolism, they regulate the architecture shaping and developmental transition when heterogeneously expressed in Arabidopsis and may provide potentially valuable characteristics for high yield breeding of crops in the future. Carbon 94-100 SNF1-related protein kinase Zea mays 35-42 30811182-1 2019 Advanced treatment trains based on oxidation, biofiltration, and/or granular activated carbon (Ox/BAF/GAC) are an attractive alternative to those based on microfiltration, reverse osmosis, and advanced oxidation (MF/RO/AOP) for the potable reuse of municipal wastewater effluents, but their effluent quality is difficult to validate with respect to chemical contaminants. Carbon 87-93 BAF nuclear assembly factor 1 Homo sapiens 98-101 30958856-4 2019 Overexpression of SFH1 in the strain defective in Psd1 restored its growth on non-fermentable carbon sources and increased the intracellular and mitochondrial PE levels. Carbon 94-100 Sfh1p Saccharomyces cerevisiae S288C 18-22 30992998-7 2019 While the gdh3/gdh3 mutant could grow on these carbon and nitrogen sources, the strain was locked in the yeast morphology in proline-containing medium. Carbon 47-53 glutamate dehydrogenase (NADP(+)) GDH3 Saccharomyces cerevisiae S288C 10-14 30992998-7 2019 While the gdh3/gdh3 mutant could grow on these carbon and nitrogen sources, the strain was locked in the yeast morphology in proline-containing medium. Carbon 47-53 glutamate dehydrogenase (NADP(+)) GDH3 Saccharomyces cerevisiae S288C 15-19 30992998-10 2019 It appears that the disequilibrium of cofactors in the gdh3/gdh3 mutant leads to characteristic proline degradation in the central carbon metabolism. Carbon 131-137 glutamate dehydrogenase (NADP(+)) GDH3 Saccharomyces cerevisiae S288C 55-59 30992998-10 2019 It appears that the disequilibrium of cofactors in the gdh3/gdh3 mutant leads to characteristic proline degradation in the central carbon metabolism. Carbon 131-137 glutamate dehydrogenase (NADP(+)) GDH3 Saccharomyces cerevisiae S288C 60-64 30637965-0 2019 Atomic Layer Deposition of NiOOH/Ni(OH)2 on PIM-1-Based N-Doped Carbon Nanofibers for Electrochemical Water Splitting in Alkaline Medium. Carbon 64-70 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 44-49 30637965-3 2019 Well-aligned high-surface-area electrospun polymers of intrinsic microporosity (PIM-1)-based nitrogen-doped carbon nanofibers were prepared as a free-standing flexible electrode. Carbon 108-114 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 80-85 30637965-8 2019 This study provides insight into the design of 1D-aligned N-doped PIM-1 electrospun carbon nanofibers as a flexible and free-standing NiOOH/Ni(OH)2 decorated electrode as a highly stable nanocatalyst for water splitting in an alkaline medium. Carbon 84-90 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 66-71 30821452-5 2019 Theoretical calculations predicted that electron-withdrawing groups prefer an attachment to the sp3-hybridized carbon atom rather than the nitrogen atom in indoliums. Carbon 111-117 Sp3 transcription factor Homo sapiens 96-99 30821452-6 2019 For the electron-donating groups, the two isomers bonded to the sp3-hybridized carbon or nitrogen atom are almost isoenergetic. Carbon 79-85 Sp3 transcription factor Homo sapiens 64-67 30821452-7 2019 When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom. Carbon 34-40 Sp3 transcription factor Homo sapiens 19-22 30821452-7 2019 When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom. Carbon 34-40 Sp3 transcription factor Homo sapiens 174-177 30821452-7 2019 When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom. Carbon 34-40 Sp3 transcription factor Homo sapiens 174-177 30821452-7 2019 When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom. Carbon 189-195 Sp2 transcription factor Homo sapiens 10-13 30821452-7 2019 When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom. Carbon 189-195 Sp3 transcription factor Homo sapiens 19-22 30821452-7 2019 When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom. Carbon 189-195 Sp3 transcription factor Homo sapiens 174-177 30821452-7 2019 When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom. Carbon 189-195 Sp3 transcription factor Homo sapiens 174-177 30835121-2 2019 This strategy provides the synthesis of valuable SCF3-substituted quinoline and isoquinoline systems via the construction of one C(sp2)-SCF3 bond and one C-N bond within one process. Carbon 50-51 Sp2 transcription factor Homo sapiens 129-134 30768759-3 2019 Among these three candidate genes, CNOT2 maintains the structural integrity of the carbon catabolite repressor 4 (CCR4)-negative on TATA (NOT) complex, which plays a key role in regulating global gene expression, and is essential for the enzymatic activity of the CCR4-NOT complex. Carbon 83-89 CCR4-NOT transcription complex subunit 2 Homo sapiens 35-40 30724472-4 2019 This is the first example of Fe-Co-N-C electrocatalysts fabricated from a cationic CoII -based MOF precursor that dopes the Fe element via anion-exchange, and our current work provides a new entrance towards MOF-derived transition-metal (e.g. Fe or Co) and nitrogen-codoped carbon electrocatalysts with excellent ORR activity. Carbon 274-280 mitochondrially encoded cytochrome c oxidase II Homo sapiens 83-87 30847537-0 2019 Carbon nanotubes and crystalline silica stimulate robust ROS production, inflammasome activation, and IL-1beta secretion in macrophages to induce myofibroblast transformation. Carbon 0-6 interleukin 1 beta Homo sapiens 102-110 30268669-3 2019 The results demonstrated in a step-wise manner that the phosphocholine-modified screen-printed carbon electrodes were highly responsive to the clinically required range of C-reactive protein (CRP) (0.005 - 500 mg L-1; r2 = 0.993) levels with a detection limit (3sigma/slope) of 0.001 mg L-1. Carbon 95-101 C-reactive protein Homo sapiens 172-190 30268669-3 2019 The results demonstrated in a step-wise manner that the phosphocholine-modified screen-printed carbon electrodes were highly responsive to the clinically required range of C-reactive protein (CRP) (0.005 - 500 mg L-1; r2 = 0.993) levels with a detection limit (3sigma/slope) of 0.001 mg L-1. Carbon 95-101 C-reactive protein Homo sapiens 192-195 30684751-2 2019 Adopting zinc zeolitic imidazolate framework and graphitic carbon nitride as nitrogen-sources and templates, we herein design a facile route to fabricate an oxygen (6.11%) functionalized and heavy nitrogen (23.54%) doped porous carbon (NOC-800) with high graphitization degree, high surface area and total pore volume. Carbon 59-65 nocturnin Homo sapiens 236-239 30623813-3 2019 First, amino groups were grafted onto the carbon shell to facilitate noncovalent sorption of bovine serum albumin (BSA). Carbon 42-48 albumin Homo sapiens 100-113 30731360-4 2019 Among them, the compound N"-(4-methylbenzylidene)-5-phenylisoxazole-3-carbohydrazide (6c) exhibited the most potent inhibitory activity towards MAO-B. Carbon 86-88 monoamine oxidase B Mus musculus 144-149 31123231-0 2019 Agar-agar impregnated on porous activated carbon as a new adsorbent for Pb(II) removal. Carbon 42-48 submaxillary gland androgen regulated protein 3B Homo sapiens 72-78 30882825-2 2019 Here, we report on multifunctional carbon dots that can chelate Cu(ii) ions, suppress Abeta aggregation, and photooxygenate Abeta peptides. Carbon 35-41 amyloid beta precursor protein Homo sapiens 86-91 30882825-4 2019 For effective conjugation with Cu(ii)-bound Abeta complexes, we have designed carbon dots that possess nitrogen (N)-containing polyaromatic functionalities on their surface by employing o-phenylenediamine (OPD) as a polymerization precursor. Carbon 78-84 amyloid beta precursor protein Homo sapiens 44-49 30882825-6 2019 Furthermore, the pOPD-derived carbon dots exhibited dramatically enhanced absorption and fluorescence upon coordination with Cu(ii) ions and effectively photooxygenated Abeta peptides. Carbon 30-36 amyloid beta precursor protein Homo sapiens 169-174 30882825-8 2019 This work demonstrates the potential of carbon dots as a multifunctional beta-sheet breaker and provides a promising anti-amyloidogenic strategy for future Abeta-targeted AD treatments. Carbon 40-46 amyloid beta precursor protein Homo sapiens 156-161 30677605-2 2019 In this study, lignin was successfully converted into porous carbon (LPC) in one step by microwave heating combined with the use of humidified nitrogen. Carbon 61-67 proprotein convertase subtilisin/kexin type 7 Homo sapiens 69-72 30707784-2 2019 It was found that the nanomaterial possesses a structure dominated by sp2 carbon atoms in a non-ordered carbon network formed by small clusters (<2 nm) of a carbonaceous material. Carbon 74-80 Sp2 transcription factor Homo sapiens 70-73 30793885-1 2019 A hybrid sp2-sp3 electrochemical sensor comprising patterned regions of nondiamond-carbon (sp2) in a boron doped diamond (sp3) matrix is described for the simultaneous voltammetric detection of dissolved oxygen (DO) and pH in buffered aqueous solutions. Carbon 83-89 Sp2 transcription factor Homo sapiens 9-12 30793885-1 2019 A hybrid sp2-sp3 electrochemical sensor comprising patterned regions of nondiamond-carbon (sp2) in a boron doped diamond (sp3) matrix is described for the simultaneous voltammetric detection of dissolved oxygen (DO) and pH in buffered aqueous solutions. Carbon 83-89 Sp3 transcription factor Homo sapiens 13-16 30793885-1 2019 A hybrid sp2-sp3 electrochemical sensor comprising patterned regions of nondiamond-carbon (sp2) in a boron doped diamond (sp3) matrix is described for the simultaneous voltammetric detection of dissolved oxygen (DO) and pH in buffered aqueous solutions. Carbon 83-89 Sp2 transcription factor Homo sapiens 91-94 30793885-1 2019 A hybrid sp2-sp3 electrochemical sensor comprising patterned regions of nondiamond-carbon (sp2) in a boron doped diamond (sp3) matrix is described for the simultaneous voltammetric detection of dissolved oxygen (DO) and pH in buffered aqueous solutions. Carbon 83-89 Sp3 transcription factor Homo sapiens 122-125 30793885-2 2019 Using a laser micropatterning process it is possible to write mechanically robust regions of sp2 carbon into a BDD electrode. Carbon 97-103 Sp2 transcription factor Homo sapiens 93-96 30793885-3 2019 These regions both promote the electrocatalytic reduction of oxygen and facilitate the proton coupled electron transfer of quinone groups, integrated into the surface of the sp2 carbon. Carbon 178-184 Sp2 transcription factor Homo sapiens 174-177 30827109-2 2019 In this work, platinized carbon nanoelectrodes were used to detect, characterize, and quantify for the first time the intracellular production rates of the four primary ROS/RNS (i.e., H2O2, ONOO-, NO , and NO2-) inside single phagolysosomes of living RAW 264.7 murine macrophages stimulated by interferon-gamma and lipopolysaccharide (IFN-gamma/LPS) to mimic an in vivo inflammatory activation. Carbon 25-31 interferon gamma Mus musculus 294-310 30848914-0 2019 Photoluminescence Intensity Fluctuations and Temperature-Dependent Decay Dynamics of Individual Carbon Nanotube sp3 Defects. Carbon 96-102 Sp3 transcription factor Homo sapiens 112-115 30848914-1 2019 Recent demonstration of room temperature, telecommunication wavelength single photon generation by sp3 defects of single wall carbon nanotubes established these defects as a new class of quantum materials. Carbon 126-132 Sp3 transcription factor Homo sapiens 99-102 30903376-9 2019 Carbon screen printed electrode (CSPE) was modified with nitrogen doped graphene (NG), gold nanoparticles (AuNPs), cyclometallated iridium(III)-polyvinylpyridine polymer nanoparticles, ionic liquid and bovine serum albumin. Carbon 0-6 albumin Homo sapiens 209-222 30903401-5 2019 Interestingly, it was found that the carbon atoms produced by thermal decomposition of ethanol form sp2 carbon network on SiO2 surface thereby forming nanographene flakes via an intermediate carbon-based nanostructured state carbon nanotube. Carbon 37-43 Sp2 transcription factor Homo sapiens 100-103 30903401-5 2019 Interestingly, it was found that the carbon atoms produced by thermal decomposition of ethanol form sp2 carbon network on SiO2 surface thereby forming nanographene flakes via an intermediate carbon-based nanostructured state carbon nanotube. Carbon 104-110 Sp2 transcription factor Homo sapiens 100-103 30903401-5 2019 Interestingly, it was found that the carbon atoms produced by thermal decomposition of ethanol form sp2 carbon network on SiO2 surface thereby forming nanographene flakes via an intermediate carbon-based nanostructured state carbon nanotube. Carbon 104-110 Sp2 transcription factor Homo sapiens 100-103 30903401-5 2019 Interestingly, it was found that the carbon atoms produced by thermal decomposition of ethanol form sp2 carbon network on SiO2 surface thereby forming nanographene flakes via an intermediate carbon-based nanostructured state carbon nanotube. Carbon 104-110 Sp2 transcription factor Homo sapiens 100-103 30827109-2 2019 In this work, platinized carbon nanoelectrodes were used to detect, characterize, and quantify for the first time the intracellular production rates of the four primary ROS/RNS (i.e., H2O2, ONOO-, NO , and NO2-) inside single phagolysosomes of living RAW 264.7 murine macrophages stimulated by interferon-gamma and lipopolysaccharide (IFN-gamma/LPS) to mimic an in vivo inflammatory activation. Carbon 25-31 interferon gamma Mus musculus 335-344 30829473-0 2019 sp2-Hybridized Carbon-Containing Block Copolymer Templated Synthesis of Mesoporous Semiconducting Metal Oxides with Excellent Gas Sensing Property. Carbon 15-21 Sp2 transcription factor Homo sapiens 0-3 31087989-3 2019 Results showed that the average effluent COD concentration of the carbon removal system was 120 mg L-1 and that the subsequent nitrosation system and ANAMMOX system would not be adversely affected by the effluent COD. Carbon 66-72 immunoglobulin kappa variable 1-16 Homo sapiens 99-102 30829473-6 2019 To solve this challenge, we designed new amphiphilic block copolymers with high content of sp2-hybridized carbon in the hydrophobic segments that were relatively stable and could be in situ converted into residual carbon to support the mesoporous structure, via living free radical polymerization. Carbon 106-112 Sp2 transcription factor Homo sapiens 91-94 30829473-6 2019 To solve this challenge, we designed new amphiphilic block copolymers with high content of sp2-hybridized carbon in the hydrophobic segments that were relatively stable and could be in situ converted into residual carbon to support the mesoporous structure, via living free radical polymerization. Carbon 214-220 Sp2 transcription factor Homo sapiens 91-94 30829473-7 2019 We developed a variety of novel synthesis methods based on sp2-hybridized carbon-containing block copolymer, such as ligand-assisted assembly and resol-assisted assembly strategies, achieving a controllable and versatile synthesis of mesoporous semiconducting metal oxides with excellent gas sensing performance. Carbon 74-80 Sp2 transcription factor Homo sapiens 59-62 30829473-8 2019 In this Account, we first outline the features of sp2-hybridized carbon-containing block copolymers synthesized via living free radical polymerization, particularly their pyrolysis behavior in converting into residual carbon. Carbon 65-71 Sp2 transcription factor Homo sapiens 50-53 30829473-8 2019 In this Account, we first outline the features of sp2-hybridized carbon-containing block copolymers synthesized via living free radical polymerization, particularly their pyrolysis behavior in converting into residual carbon. Carbon 218-224 Sp2 transcription factor Homo sapiens 50-53 30829473-13 2019 These newly developed soft-templating synthesis methods that rely on sp2-hybridized carbon-containing block copolymers will open a new avenue for the design and application of ordered mesoporous semiconducting metal oxides in various fields. Carbon 84-90 Sp2 transcription factor Homo sapiens 69-72 30857164-0 2019 An Exfoliated Graphite-Based Electrochemical Immunosensor on a Dendrimer/Carbon Nanodot Platform for the Detection of Carcinoembryonic Antigen Cancer Biomarker. Carbon 73-79 CEA cell adhesion molecule 3 Homo sapiens 118-142 30857164-1 2019 An electrochemical immunosensor for the quantification of carcinoembryonic antigen (CEA) using a nanocomposite of polypropylene imine dendrimer (PPI) and carbon nanodots (CNDTs) on an exfoliated graphite electrode (EG) is reported. Carbon 154-160 CEA cell adhesion molecule 3 Homo sapiens 58-82 30857164-1 2019 An electrochemical immunosensor for the quantification of carcinoembryonic antigen (CEA) using a nanocomposite of polypropylene imine dendrimer (PPI) and carbon nanodots (CNDTs) on an exfoliated graphite electrode (EG) is reported. Carbon 154-160 CEA cell adhesion molecule 3 Homo sapiens 84-87 30893314-10 2019 FTCD is critical for catabolism of histidine, a process that generates one-carbon units that can enter the one-carbon/folate cycle, which provides methyl groups for arsenic metabolism. Carbon 75-81 formimidoyltransferase cyclodeaminase Homo sapiens 0-4 30893314-10 2019 FTCD is critical for catabolism of histidine, a process that generates one-carbon units that can enter the one-carbon/folate cycle, which provides methyl groups for arsenic metabolism. Carbon 111-117 formimidoyltransferase cyclodeaminase Homo sapiens 0-4 31087998-16 2019 Fine root biomass and the soil carbon-nitrogen ratio were critical factors for variation of soil respiration under acid rain. Carbon 31-37 Ras interacting protein 1 Homo sapiens 120-124 31459681-0 2019 Two-Dimensional Anisotropic C10 Carbon Allotrope with Mechanically Tunable Band Gap. Carbon 32-38 homeobox C10 Homo sapiens 28-31 30866423-4 2019 The as-synthesized CQDs had a size distribution from 2.0-6.0 nm and had high percentage of sp2 and sp3 carbon groups. Carbon 103-109 Sp3 transcription factor Homo sapiens 99-102 31459681-1 2019 A high band gap, two-dimensional (2D) twisted octagonal (TO-)C10 allotrope of carbon is proposed. Carbon 78-84 homeobox C10 Homo sapiens 61-64 31459681-3 2019 TO-C10 also possesses one of the highest 2.94 eV (3.97 eV by HSE06) indirect band gap among reported 2D allotropes of carbon. Carbon 118-124 homeobox C10 Homo sapiens 3-6 30658969-0 2019 Inactivating Mutations in Irc7p Are Common in Wine Yeasts, Attenuating Carbon-Sulfur beta-Lyase Activity and Volatile Sulfur Compound Production. Carbon 71-77 cysteine-S-conjugate beta-lyase IRC7 Saccharomyces cerevisiae S288C 26-31 30259581-2 2019 Graphdiyne, the rising-star carbon allotrope, is a big family with many members, and first realized the coexistence of sp- and sp2 -hybridized carbon atoms in a 2D planar structure. Carbon 143-149 Sp2 transcription factor Homo sapiens 127-130 30714720-1 2019 Enolase is a glycolytic metalloenzyme involved in carbon metabolism. Carbon 50-56 Enolase Escherichia coli 0-7 30698958-0 2019 A Pilot-Scale Field Study: In Situ Treatment of PCB-Impacted Sediments with Bioamended Activated Carbon. Carbon 97-103 pyruvate carboxylase Homo sapiens 48-51 30777759-1 2019 The first enantioselective sequential phosphine-catalyzed (SPC as abbreviation) mode for the formation of tetrahydroquinolines with an ethynyl-substituted all-carbon quaternary stereogenic center is reported. Carbon 159-165 proline rich protein gene cluster Homo sapiens 59-62 30660931-5 2019 A diazonium modified screen-printed carbon electrode immobilized with a DNA sequence related to the p53 tumour suppressor gene, the most commonly affected gene in human UV-induced skin cancer, was applied as an electrochemical DNA sensor. Carbon 36-42 tumor protein p53 Homo sapiens 100-103 30476532-4 2019 Non-cytotoxic doses of carbon nanoparticles but not of bigger carbon particles led to an irreversible reduction of the proliferative capacity accompanied by the accumulation of the cell cycle blocking proteins p21 and p16 as well as a loss of both redox sensitive histone deacetylase SIRT1 and connexin-43. Carbon 23-29 cyclin dependent kinase inhibitor 2A Homo sapiens 218-221 30312759-8 2019 Multiwall carbon nanotubes of ~50 nm-diameter, additionally adsorbing transferrin, are similarly carcinogenic to mesothelial cells in rodents and were thus classified as Group 2B carcinogens. Carbon 10-16 transferrin Homo sapiens 70-81 30324259-6 2019 Multi-walled carbon nanotubes scaffold films (MWSFs) yielded the best analytical performance in terms of sensitivity with a good limit of detection of 0.6 mg L-1 for AGP determination in serum samples, in less than 20 min. Carbon 13-19 immunoglobulin kappa variable 1-16 Homo sapiens 158-161 30345459-11 2019 CONCLUSIONS: Our data demonstrate that increasing the alpha-carbon chain length of methylone creates "hybrid" transporter compounds which act as DAT blockers but SERT substrates. Carbon 60-66 solute carrier family 6 member 4 Rattus norvegicus 162-166 30773846-4 2019 Statistical analyses of Raman spectroscopy and X-ray photoelectron spectroscopy indicate a low number of sp3 carbon atoms on the order of 2% before and 4% after covalent functionalization. Carbon 109-115 Sp3 transcription factor Homo sapiens 105-108 30447588-5 2019 It is observed that, in general, OC3 and EC1 were the dominant thermally evolved carbon mass fractions. Carbon 81-87 one cut homeobox 3 Homo sapiens 33-36 30773846-6 2019 The observed doping effects and theoretical studies suggest sp2 hybridization for the carbon atoms involved in the [2+1] cycloaddition reaction leading to preservation of the pi-conjugated system and enhancing conductivity via n-type doping through the bridging N-atom. Carbon 86-92 Sp2 transcription factor Homo sapiens 60-63 30753065-4 2019 We report unique solutions to the challenge of increasing both the chemical diversity of these libraries and their C(sp3) carbon counts by merging Ni/photoredox dual catalytic C(sp2)-C(sp3) cross-coupling as well as photoredox-catalyzed radical/polar crossover alkylation protocols with DELs. Carbon 122-128 Sp2 transcription factor Homo sapiens 176-181 29473769-2 2019 Aldehyde oxidase (AO enzymes)-mediated oxidation predominantly occurs at a carbon atom adjacent to the nitrogen on aromatic azaheterocycles. Carbon 75-81 aldehyde oxidase 1 Homo sapiens 0-16 30863383-1 2019 The ubiquitous and highly abundant glycolytic enzyme D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pivotal for the energy and carbon metabolism of most organisms, including human pathogenic bacteria. Carbon 134-140 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 97-102 31015939-5 2019 Subsequent nucleophilic trapping of these species by various sp2-hybridized N-nucleophiles delivered three classes (external salts, inner salts, and neutral azacycles) of five-membered azacycles bearing a tetrasubstituted saturated carbon center, as a result of [4 + 1] annulation with the alkyne being a one-carbon synthon. Carbon 232-238 Sp2 transcription factor Homo sapiens 61-64 31015939-5 2019 Subsequent nucleophilic trapping of these species by various sp2-hybridized N-nucleophiles delivered three classes (external salts, inner salts, and neutral azacycles) of five-membered azacycles bearing a tetrasubstituted saturated carbon center, as a result of [4 + 1] annulation with the alkyne being a one-carbon synthon. Carbon 309-315 Sp2 transcription factor Homo sapiens 61-64 30580512-6 2019 Moreover, a full-cell battery employing the MoS3/r-GO cathode with a silicon-carbon composite anode displays a 3-5 times higher energy density (1725 Wh kg-1/7100 Wh L-1) than present LIBs. Carbon 77-83 immunoglobulin kappa variable 1-16 Homo sapiens 165-168 30796298-6 2019 Herein, carbon screen-printed electrodes were modified with cytochrome c nitrite reductase together with glucose oxidase and catalase, so that nitrite cathodic detection could be performed by cyclic voltammetry under ambient air. Carbon 8-14 cytochrome c, somatic Homo sapiens 60-72 30795812-12 2019 CONCLUSIONS: Priming with poly I:C- or IFN-gamma improved the therapeutic effects of WJ-MSCs in a murine model of AD. Carbon 0-1 interferon gamma Mus musculus 39-48 30796298-6 2019 Herein, carbon screen-printed electrodes were modified with cytochrome c nitrite reductase together with glucose oxidase and catalase, so that nitrite cathodic detection could be performed by cyclic voltammetry under ambient air. Carbon 8-14 catalase Homo sapiens 125-133 30796533-0 2019 Fluorometric determination of the activity of alkaline phosphatase and its inhibitors based on ascorbic acid-induced aggregation of carbon dots. Carbon 132-138 alkaline phosphatase, placental Homo sapiens 46-66 30796533-11 2019 Graphical abstract Schematic presentation of the nitrogen and boron co-doped carbon dot-based fluorometric method for determination of alkaline phosphatase (ALP) activity. Carbon 77-83 alkaline phosphatase, placental Homo sapiens 135-155 30796533-11 2019 Graphical abstract Schematic presentation of the nitrogen and boron co-doped carbon dot-based fluorometric method for determination of alkaline phosphatase (ALP) activity. Carbon 77-83 alkaline phosphatase, placental Homo sapiens 157-160 30689356-3 2019 Their kinetics were determined by monitoring the consumption of H2O2 with a nitrogen-doped carbon nanotubes (N-CNT) electrode, which could detect 0.50 muM H2O2 at -0.20 V. The unique design of internally calibrated electrochemical continuous enzyme assay (ICECEA) and electrode stability allowed use of one N-CNT electrode for over half a year to reliably determine MPO. Carbon 91-97 myeloperoxidase Homo sapiens 366-369 30476185-3 2019 Using a field-effect transistor (FET)-type biosensor based on carbon nanofibers, in the present study we demonstrate that Haa1 and War1 directly bind to various weak acid anions with different affinities. Carbon 62-68 War1p Saccharomyces cerevisiae S288C 131-135 30787280-2 2019 Fundamentally, they are important systems to study the convergence of physico-chemical properties of all-carbon sp2-frameworks in the one-dimensional limit; and by virtue of having a zigzag edge topology they also provide a fertile playground to explore magnetism in graphenic nanostructures. Carbon 105-111 Sp2 transcription factor Homo sapiens 112-115 30742151-3 2019 Among the polycyclic aromatic hydrocarbons, the centropolyindanes are special because of the saturated core of sp3-hybridised carbon atoms embedded in a three-dimensional environment of aromatic building blocks. Carbon 35-41 Sp3 transcription factor Homo sapiens 111-114 30767781-10 2019 In particular, multiple genes previously implicated in low carbon stress such as asparagine synthetase, amino acid transporters, trehalose-6-phosphate synthase, as well as many transcription factors, were strongly upregulated. Carbon 59-65 trehalose-6-phosphate synthase Zea mays 129-159 30620788-6 2019 Porous carbon tri-doped with nitrogen, phosphorous, and oxygen exhibits a high packing density (2.13 g cm-3 ) and an exceptional volumetric energy density (36.8 Wh L-1 ) in alkaline electrolytes, making it competitive to even some Ni-MH cells. Carbon 7-13 immunoglobulin kappa variable 1-16 Homo sapiens 164-167 30694654-3 2019 We also describe Co(II) complexes with octahedral ligands derived from 1,2-dicarba- closo-hexaborane and study the effects of replacing a thiol group by a hydroxy group in both polyhedral geometries, as well as the influence of the position of the carbon atoms. Carbon 248-254 mitochondrially encoded cytochrome c oxidase II Homo sapiens 17-23 30384050-0 2019 Adsorption behavior and mechanism of Mg/Fe layered double hydroxide with Fe3O4-carbon spheres on the removal of Pb(II) and Cu(II). Carbon 79-85 submaxillary gland androgen regulated protein 3B Homo sapiens 112-129 30373012-0 2019 Simultaneous determination of Cd(II) and Pb(II) ions in honey and milk samples using a single-walled carbon nanohorns modified screen-printed electrochemical sensor. Carbon 101-107 submaxillary gland androgen regulated protein 3B Homo sapiens 30-47 30373012-5 2019 Under the optimized conditions, the linear range of the single-walled carbon nanohorns film modified electrode for both heavy metal ions varied from 1.0 to 60.0 mug L-1. Carbon 70-76 L1 cell adhesion molecule Homo sapiens 165-168 30384050-1 2019 Mg/Fe layered double hydroxide loaded with Magnetic(Fe3O4) carbon spheres (MCs@Mg/Fe-LDHs) was firstly synthesized by a facile in-situ co-precipitation method to remove Pb(II) and Cu(II) pollution. Carbon 59-65 submaxillary gland androgen regulated protein 3B Homo sapiens 169-186 30726233-3 2019 Nanoparticles were used for modification of glassy carbon electrode (GCE) and new sensor was applied for simultaneous determination of Pb(II) and Cd(II) ions in water samples with the linear sweep anodic stripping voltammetry (LSASV).The factors such as pH, deposition potential and deposition time are optimized. Carbon 51-57 submaxillary gland androgen regulated protein 3B Homo sapiens 135-141 30741341-0 2019 Voltammetric immunosensor for E-cadherin promoter DNA methylation using a Fe3O4-citric acid nanocomposite and a screen-printed carbon electrode modified with poly(vinyl alcohol) and reduced graphene oxide. Carbon 127-133 cadherin 1 Homo sapiens 30-40 30803613-1 2019 Pyrolysis offers the possibility to convert waste tires into liquid and gaseous fractions as well as a carbon-rich solid (CBp), which contains the original carbon black (CB) and the inorganic compounds used in tire manufacture. Carbon 103-109 CREB binding protein Homo sapiens 122-125 30803613-1 2019 Pyrolysis offers the possibility to convert waste tires into liquid and gaseous fractions as well as a carbon-rich solid (CBp), which contains the original carbon black (CB) and the inorganic compounds used in tire manufacture. Carbon 103-109 CREB binding protein Homo sapiens 122-124 30803613-6 2019 An ash content of 4.9 wt% was obtained by using 60 min of soaking time, 60 C of temperature, 10 mL/g of reagent/CBp ratio and HCl 4 M. The demineralized CBp (dCBp) showed a carbon content of 92.9 wt%, while the FRX analysis indicated that SiO2 is the major component into the ash. Carbon 174-180 CREB binding protein Homo sapiens 154-157 30694284-2 2019 Only during calciation of Dipp-N[double bond, length as m-dash]C(H)-N(H)-C2H4-Py (1a), the heteroleptic intermediate [{(Me3Si)2N}Ca{Dipp-N[double bond, length as m-dash]C(R)-N-C2H4-Py}]2 (2a") has been observed. Carbon 63-64 nudix hydrolase 3 Homo sapiens 26-30 30694284-2 2019 Only during calciation of Dipp-N[double bond, length as m-dash]C(H)-N(H)-C2H4-Py (1a), the heteroleptic intermediate [{(Me3Si)2N}Ca{Dipp-N[double bond, length as m-dash]C(R)-N-C2H4-Py}]2 (2a") has been observed. Carbon 63-64 nudix hydrolase 3 Homo sapiens 132-136 30632576-3 2019 This strategy led to an original ortho-metallated complex where the Pd center is bonded to four carbon atoms of three different natures: carbenic (sp2), arylic (sp2), and chiral ylidic (sp3). Carbon 96-102 Sp2 transcription factor Homo sapiens 147-150 30733534-3 2019 It is demonstrated that the chemical composition of the carbon structures (i.e. percentage of oxygen groups, sp2 and sp3 carbon atoms) plays a key role in the improvement of the carbon-based devices. Carbon 56-62 Sp2 transcription factor Homo sapiens 109-112 30733534-3 2019 It is demonstrated that the chemical composition of the carbon structures (i.e. percentage of oxygen groups, sp2 and sp3 carbon atoms) plays a key role in the improvement of the carbon-based devices. Carbon 56-62 Sp3 transcription factor Homo sapiens 117-120 30778350-0 2019 Protective Effects of Aryl Hydrocarbon Receptor Signaling in Celiac Disease Mucosa and in Poly I:C-Induced Small Intestinal Atrophy Mouse Model. Carbon 61-62 aryl-hydrocarbon receptor Mus musculus 22-47 30715613-2 2019 Electroactive molybdophosphate anions were precipitated in-situ on a glassy carbon electrode (GCE) via catalytic hydrolysis by alkaline phosphatase (ALP). Carbon 76-82 alkaline phosphatase, placental Homo sapiens 127-147 30715613-2 2019 Electroactive molybdophosphate anions were precipitated in-situ on a glassy carbon electrode (GCE) via catalytic hydrolysis by alkaline phosphatase (ALP). Carbon 76-82 alkaline phosphatase, placental Homo sapiens 149-152 30593490-6 2019 Dot6 was required for carbon-source modulation of cell size, and it is regulated at the level of nuclear localization by the TOR pathway. Carbon 22-28 Dot6p Saccharomyces cerevisiae S288C 0-4 30712159-0 2019 An origami paper-based electrochemical immunoassay for the C-reactive protein using a screen-printed carbon electrode modified with graphene and gold nanoparticles. Carbon 101-107 C-reactive protein Homo sapiens 59-77 30663244-5 2019 The sample presents 2D mesoporous structure and is exactly composed of sp and sp2 -hybridized carbon atoms as the gamma-graphyne structure. Carbon 94-100 Sp2 transcription factor Homo sapiens 78-81 30073660-4 2019 As the WPR was reduced from 12 to 2 L kg-1 , the specific electric energy consumption linearly decreased from 1.93 to 0.39 Wh g-1 and the carbon footprint and eutrophication potential of pasta cooking lessened by approximately 80% and 50%, respectively. Carbon 138-144 solute carrier family 45 member 1 Homo sapiens 187-192 30243732-7 2019 Comparison of MWCNT exposure methods, M-7 ALI exposure versus M-7 submerged exposure, yielded protein enrichment in pathways known to be associated with carbon nanotube exposure stress response, such as acute phase response signaling and NRF2-mediated oxidative stress response. Carbon 153-159 NFE2 like bZIP transcription factor 2 Homo sapiens 238-242 30551158-4 2019 Despite this, phloem sap is not commonly employed due to an incomplete understanding of transport and post-photosynthetic processes and their effects on chemical concentrations and carbon isotope discrimination. Carbon 181-187 SH2 domain containing 1A Homo sapiens 21-24 29663794-1 2019 Graphyne and its family are new carbon allotropes in 2D form with both sp and sp2 hybridization. Carbon 32-38 Sp2 transcription factor Homo sapiens 78-81 30126018-2 2019 In most cases, their phosphorus atoms are bound to heteroatoms such as oxygen or nitrogen (PN3 or PN2 O), whereas homoleptic coordination by three sp2 -hybridized carbon atoms has been reported only recently. Carbon 163-169 Sp2 transcription factor Homo sapiens 147-150 29845862-1 2019 Graphdiyne (GDY) is a two-dimensional (2D) carbon allotrope consisting of sp2- and sp-hybridized carbon atoms. Carbon 43-49 Sp2 transcription factor Homo sapiens 74-77 30488662-1 2019 Pressure-induced polymerization (PIP) of aromatics is a novel method for constructing sp3 -carbon frameworks, and nanothreads with diamond-like structures were synthesized by compressing benzene and its derivatives. Carbon 91-97 prolactin induced protein Homo sapiens 33-36 30488662-1 2019 Pressure-induced polymerization (PIP) of aromatics is a novel method for constructing sp3 -carbon frameworks, and nanothreads with diamond-like structures were synthesized by compressing benzene and its derivatives. Carbon 91-97 Sp3 transcription factor Homo sapiens 86-89 30566121-1 2019 The organometallic complex (fac-Mn(apbpy)(CO)3Br) (apbpy = 4-(4-aminophenyl)-2,2"-bipyridine) grafted electrochemically onto carbon cloth serves as an electrocatalyst in the aqueous reduction of CO2 to syngas. Carbon 125-131 FA complementation group C Homo sapiens 28-31 30615436-0 2019 Electronically Triggered Switchable Binding Modes of the C-Organonitroso (ArNO) Moiety on the {Ru(acac)2} Platform. Carbon 57-58 cytohesin 2 Homo sapiens 74-78 30696132-4 2019 The root mean square errors of cross validation (RMSECVs) of boron and carbon isotopes (11BO, 10BO, 12CN, and 13CN) improved to 2.632, 5.721, 5.990, and 1.543 at.%, as compared with 16.96, 35.79, 57.10, and 13.89 at.%, respectively, obtained in the case without LIRF. Carbon 71-77 ring finger protein 39 Homo sapiens 262-266 30566121-0 2019 Electrochemical CO2 reduction in water at carbon cloth electrodes functionalized with a fac-Mn(apbpy)(CO)3Br complex. Carbon 42-48 FA complementation group C Homo sapiens 88-91 30569701-1 2019 A novel paper electrode-based flexible pressure sensor modified with multiwalled carbon nanotubes was designed for point-of-care (POC) immunoassay of carcinoembryonic antigen (CEA) with digital multimeter readout. Carbon 81-87 CEA cell adhesion molecule 3 Homo sapiens 150-174 30461145-0 2019 A Nitrogen-Rich 2D sp2 -Carbon-Linked Conjugated Polymer Framework as a High-Performance Cathode for Lithium-Ion Batteries. Carbon 24-30 Sp2 transcription factor Homo sapiens 19-22 30114588-1 2019 Activated carbon (AC) is commonly used in faucet and pitcher filters for lead (Pb(II)) removal in homes. Carbon 10-16 submaxillary gland androgen regulated protein 3B Homo sapiens 79-85 30114588-4 2019 Pb(II) was inner-spherically adsorbed onto both AC and metal oxides surfaces. Carbon 48-50 submaxillary gland androgen regulated protein 3B Homo sapiens 0-6 30114588-5 2019 Among various metal ions, calcium (Ca(II)) demonstrated dramatic effects on Pb(II) removal ability of AC, while it had no effect on Pb(II) adsorption by metal oxides. Carbon 102-104 submaxillary gland androgen regulated protein 3B Homo sapiens 76-82 30348387-1 2019 In this work, sample preparation of carbon nanotubes (CNTs) for further determination of inorganic contaminants was investigated using a microwave-assisted wet digestion single reaction chamber system (MAWD-SRC). Carbon 36-42 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 207-210 30461145-3 2019 Profiting from the shape-persistent framework of 2D CCP-HATN integrated with the electrochemical redox-active HATN and the robust sp2 carbon-carbon linkage, 2D CCP-HATN hybridized with carbon nanotubes shows a high capacity of 116 mA h g-1 , with high utilization of its redox-active sites and superb cycling stability (91 % after 1000 cycles) and rate capability (82 %, 1.0 A g-1 vs. 0.1 A g-1 ) as an organic cathode material for lithium-ion batteries. Carbon 134-140 Sp2 transcription factor Homo sapiens 130-133 30461145-1 2019 A two-dimensional (2D) sp2 -carbon-linked conjugated polymer framework (2D CCP-HATN) has a nitrogen-doped skeleton, a periodical dual-pore structure and high chemical stability. Carbon 28-34 Sp2 transcription factor Homo sapiens 23-26 30543406-2 2019 Using a combination of experiments and high-fidelity molecular dynamics (MD) simulations, it is shown here that the hydrophilization of the sp2 carbon structure, induced by the presence of the C-N bonds, decreases the pure water permeance in CNNTs when compared with pristine and turbostratic carbon nanotubes (CNTs). Carbon 144-150 Sp2 transcription factor Homo sapiens 140-143 30543406-2 2019 Using a combination of experiments and high-fidelity molecular dynamics (MD) simulations, it is shown here that the hydrophilization of the sp2 carbon structure, induced by the presence of the C-N bonds, decreases the pure water permeance in CNNTs when compared with pristine and turbostratic carbon nanotubes (CNTs). Carbon 193-194 Sp2 transcription factor Homo sapiens 140-143 30623724-9 2019 In conclusion, TGF-b1 produces a metabolic reprogramming in renal fibroblasts, with less H3 acetylation through reduced acetylation, increased deacetylation and changes in carbon availability. Carbon 172-178 transforming growth factor, beta 1 Rattus norvegicus 15-21 30543406-2 2019 Using a combination of experiments and high-fidelity molecular dynamics (MD) simulations, it is shown here that the hydrophilization of the sp2 carbon structure, induced by the presence of the C-N bonds, decreases the pure water permeance in CNNTs when compared with pristine and turbostratic carbon nanotubes (CNTs). Carbon 293-299 Sp2 transcription factor Homo sapiens 140-143 30622241-6 2019 Neutralization of TNF-alpha or prior depletion of macrophages were able to prevent the appearance of apoptosis of hepatocytes in poly I:C-challenged Ripk1LPC-KO mice. Carbon 136-137 tumor necrosis factor Mus musculus 18-27 30627790-0 2019 Boron doped carbon dots as a multifunctional fluorescent probe for sorbate and vitamin B12. Carbon 12-18 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 87-90 30622241-6 2019 Neutralization of TNF-alpha or prior depletion of macrophages were able to prevent the appearance of apoptosis of hepatocytes in poly I:C-challenged Ripk1LPC-KO mice. Carbon 136-137 receptor (TNFRSF)-interacting serine-threonine kinase 1 Mus musculus 149-160 32166225-1 2019 Carbon nanotube (CNT) grafted glass fiber reinforced epoxy nanocomposites (GFRP) present a range of stiffnesses (MPa to GPa) and length scales (mum to nm) at the fiber-matrix interface. Carbon 0-6 glycophorin A (MNS blood group) Homo sapiens 120-123 30623249-4 2019 Carbon-supported PtNi-modified glassy carbon electrode (PtNi/C electrode) showed a broad CA detecting range (from 0.75 to 591.783 muM), a low detection limit (0.5 muM), and excellent stability. Carbon 0-6 latexin Homo sapiens 130-133 30623249-4 2019 Carbon-supported PtNi-modified glassy carbon electrode (PtNi/C electrode) showed a broad CA detecting range (from 0.75 to 591.783 muM), a low detection limit (0.5 muM), and excellent stability. Carbon 0-6 latexin Homo sapiens 163-166 30623249-4 2019 Carbon-supported PtNi-modified glassy carbon electrode (PtNi/C electrode) showed a broad CA detecting range (from 0.75 to 591.783 muM), a low detection limit (0.5 muM), and excellent stability. Carbon 38-44 latexin Homo sapiens 130-133 30623249-4 2019 Carbon-supported PtNi-modified glassy carbon electrode (PtNi/C electrode) showed a broad CA detecting range (from 0.75 to 591.783 muM), a low detection limit (0.5 muM), and excellent stability. Carbon 38-44 latexin Homo sapiens 163-166 30626049-5 2019 NMR-Spectroscopic and crystallographic analysis of the obtained complexes clearly show that the dimetallic cobalt and molybdenum complexes cause rehybridization of the alkyne carbon atoms to sp3, while in the nickel complexes one pi-bond of the alkyne is retained. Carbon 175-181 Sp3 transcription factor Homo sapiens 191-194 30284308-3 2019 An atypical bond property has been observed in this series of carbon structures, which differs from the typical sp3 , sp2 , and sp hybridizations. Carbon 62-68 Sp3 transcription factor Homo sapiens 112-115 30284308-3 2019 An atypical bond property has been observed in this series of carbon structures, which differs from the typical sp3 , sp2 , and sp hybridizations. Carbon 62-68 Sp2 transcription factor Homo sapiens 118-121 30506079-0 2019 Oxidative NHC catalysis: direct activation of beta sp3 carbons of saturated acid chlorides. Carbon 55-62 Sp3 transcription factor Homo sapiens 51-54 30506079-2 2019 The reaction involves the transformation of the beta sp3 carbon of saturated acid chlorides into an electrophilic carbon as a key step. Carbon 57-63 Sp3 transcription factor Homo sapiens 53-56 30506079-2 2019 The reaction involves the transformation of the beta sp3 carbon of saturated acid chlorides into an electrophilic carbon as a key step. Carbon 114-120 Sp3 transcription factor Homo sapiens 53-56 30176414-0 2019 Performance of Pb(II) removal by an activated carbon supported nanoscale zero-valent iron composite at ultralow iron content. Carbon 46-52 submaxillary gland androgen regulated protein 3B Homo sapiens 15-21 30176414-1 2019 Activated carbon supported nanoscale zero-valent iron composite (NZVI/AC) at ultralow iron content was synthesized and used to remove Pb(II) from aqueous solution. Carbon 10-16 submaxillary gland androgen regulated protein 3B Homo sapiens 134-140 30814086-2 2019 Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) plays a vital role in one-carbon metabolism via encoding a protein with three distinct enzymatic activities (methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formate-tetrahydrofolate ligase). Carbon 77-83 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 0-41 31122040-0 2019 Astragalus Polysaccharide Eases G1 Phase-Correlative Bystander Effects through Mediation of TGF- beta R/MAPK/ROS Signal Pathway After Carbon Ion Irradiation in BMSCs. Carbon 134-140 mitogen-activated protein kinase 1 Homo sapiens 104-108 30814086-2 2019 Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) plays a vital role in one-carbon metabolism via encoding a protein with three distinct enzymatic activities (methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formate-tetrahydrofolate ligase). Carbon 77-83 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 43-49 30183434-1 2019 OBJECTIVES: Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) plays an essential role in folate-mediated one-carbon metabolism which determines both homocysteine remethylation and de novo thymidylate biosynthesis. Carbon 110-116 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 12-53 30183434-1 2019 OBJECTIVES: Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) plays an essential role in folate-mediated one-carbon metabolism which determines both homocysteine remethylation and de novo thymidylate biosynthesis. Carbon 110-116 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 55-61 30591370-0 2019 Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes. Carbon 90-96 methionine adenosyltransferase 2A Homo sapiens 41-73 31336443-1 2019 AIMS: Paraoxonase-1 (PON1) has been shown to protect low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) against oxidative-modification and thereby might protect against coronary-artery-disease (CAD). Carbon 93-95 paraoxonase 1 Homo sapiens 6-19 31336443-1 2019 AIMS: Paraoxonase-1 (PON1) has been shown to protect low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) against oxidative-modification and thereby might protect against coronary-artery-disease (CAD). Carbon 93-95 paraoxonase 1 Homo sapiens 21-25 30327052-1 2019 Nitrogen-doped bamboo-shaped carbon nanotubes (N-BCNT) were synthesized from butylamine using the catalytic chemical vapor deposition (CCVD) process. Carbon 29-35 craniofacial development protein 1 Homo sapiens 49-53 30591370-6 2019 FINDINGS: AKBA directly interacts with methionine adenosyltransferase 2A (MAT2A), inhibited its enzyme activity, decreased level of S-adenosylmethionine (SAM) and SAM/SAH ratio, and reprogrammed one-carbon metabolism in HaCaT cells. Carbon 199-205 methionine adenosyltransferase 2A Homo sapiens 74-79 30574831-8 2019 We found four one-carbon metabolism SNPs (MTHFD1 rs2236225, TYMS rs502396, FOLH1 rs202676, GLDC rs10975681) that cumulatively explained 11.29% of the variation in average LINE-1 methylation. Carbon 18-24 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 42-48 30574831-8 2019 We found four one-carbon metabolism SNPs (MTHFD1 rs2236225, TYMS rs502396, FOLH1 rs202676, GLDC rs10975681) that cumulatively explained 11.29% of the variation in average LINE-1 methylation. Carbon 18-24 folate hydrolase 1 Homo sapiens 75-80 30552741-3 2019 Among the genes associated with the increased risk for autism is the methylenetetrahydrofolate-reductase (MTHFR) 677C>T polymorphism, which impairs one-carbon (C1) metabolic pathway efficiency. Carbon 155-161 methylenetetrahydrofolate reductase Mus musculus 69-104 30552741-3 2019 Among the genes associated with the increased risk for autism is the methylenetetrahydrofolate-reductase (MTHFR) 677C>T polymorphism, which impairs one-carbon (C1) metabolic pathway efficiency. Carbon 155-161 methylenetetrahydrofolate reductase Mus musculus 106-111 30480521-0 2019 Multiwalled Carbon Nanotubes Prevent Tumor Metastasis Through Switching M2-Polarized Macrophages to M1 via TLR4 Activation. Carbon 12-18 toll-like receptor 4 Mus musculus 107-111 30327052-3 2019 Reaction conditions such as temperature, amount of carbon source and catalyst were optimized to produce high quality N-BCNT samples. Carbon 51-57 craniofacial development protein 1 Homo sapiens 119-123 30506848-5 2019 The theoretical results agree well with the experimental data, demonstrating that tensile stresses can depress the amplitude of in-plane vibration of sp2 -bonded carbon atoms and result in the decrease in the G band intensity. Carbon 162-168 Sp2 transcription factor Homo sapiens 150-153 30235633-6 2019 The DT50 values for both herbicides increased in the GC2 amended soil with the highest organic carbon (OC) content. Carbon 95-101 solute carrier family 25 member 18 Homo sapiens 53-56 30465670-1 2018 Atomically dispersed Fe-N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells. Carbon 60-66 catalase Homo sapiens 128-136 30392661-1 2018 In this work, a highly sensitive and selective chemiluminescence (CL) aptasensor was prepared for thrombin (THR) detection based on aptamer-conjugated and hemin/G-quadruplex DNAzyme signal-amplified carbon fiber composite (HG-DNAzyme/T-Apt/SiO2@GO@CF). Carbon 199-205 coagulation factor II, thrombin Homo sapiens 98-106 30392661-1 2018 In this work, a highly sensitive and selective chemiluminescence (CL) aptasensor was prepared for thrombin (THR) detection based on aptamer-conjugated and hemin/G-quadruplex DNAzyme signal-amplified carbon fiber composite (HG-DNAzyme/T-Apt/SiO2@GO@CF). Carbon 199-205 coagulation factor II, thrombin Homo sapiens 108-111 30428987-3 2018 In this work, we successfully synthesized the peroxidase-like graphene quantum dots (GQDs) and utilized it to fabricate an enzyme-free electrochemical immunosensor towards CEA by forming a single-wall carbon nanotubes@GQDs (SWCNTs@GQDs) composite. Carbon 201-207 CEA cell adhesion molecule 3 Homo sapiens 172-175 30516956-0 2018 Zigzag sp2 Carbon Chains Passing through an sp3 Framework: A Driving Force toward Room-Temperature Ferromagnetic Graphene. Carbon 11-17 Sp2 transcription factor Homo sapiens 7-10 30516956-0 2018 Zigzag sp2 Carbon Chains Passing through an sp3 Framework: A Driving Force toward Room-Temperature Ferromagnetic Graphene. Carbon 11-17 Sp3 transcription factor Homo sapiens 44-47 30516956-4 2018 Here, we describe a method for the well-controlled sp3 functionalization of graphene to synthesize zigzag conjugated sp2 carbon chains that can act as communication pathways among radical motifs. Carbon 121-127 Sp3 transcription factor Homo sapiens 51-54 30516956-4 2018 Here, we describe a method for the well-controlled sp3 functionalization of graphene to synthesize zigzag conjugated sp2 carbon chains that can act as communication pathways among radical motifs. Carbon 121-127 Sp2 transcription factor Homo sapiens 117-120 30340688-4 2018 For the glassy carbon working electrode of the assembly the upper limit of the linear response and the lower detection limit of sequential "in-well" PCT-SVW were 1000 and 0.5 muM, respectively. Carbon 15-21 latexin Homo sapiens 175-178 30340695-2 2018 In this work, the sulfydryl aptamer selected for OH-PCB was easily immobilized on the surface of the modified glassy carbon electrode via Au-S bond due to incorporation of gold nanoparticles/poly dimethyl diallyl ammonium chloride-graphene composite. Carbon 117-123 pyruvate carboxylase Homo sapiens 52-55 31458386-1 2018 A facile hydrothermal method is adopted for the synthesis of hierarchical flowerlike nickel sulfide nanostructure materials and their composite with carbon quantum dot (NiS/C-dot) composite. Carbon 149-155 solute carrier family 5 member 5 Homo sapiens 169-172 30465670-1 2018 Atomically dispersed Fe-N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells. Carbon 60-66 catalase Homo sapiens 138-141 30465670-1 2018 Atomically dispersed Fe-N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells. Carbon 60-66 superoxide dismutase 1 Homo sapiens 147-167 30465670-1 2018 Atomically dispersed Fe-N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells. Carbon 60-66 superoxide dismutase 1 Homo sapiens 169-172 30465429-1 2018 A recent experiment [ Jin , E. ; Science 2017 , 357 , 673 - 676 ] shows that the conductivity of a two-dimensional (2D) sp2-carbon-hybridized pi-conjugated covalent organic framework (sp2-c-COF) can be enhanced by as much as 12 orders of magnitude after iodine oxidation processing. Carbon 124-130 Sp2 transcription factor Homo sapiens 120-123 31458386-4 2018 Carbon quantum dots of size 1.3 nm were synthesized from natural sources and the favorable electronic and surface property of C-dots were utilized for improvement of the supercapacitor performance of NiS. Carbon 0-6 solute carrier family 5 member 5 Homo sapiens 200-203 30465429-1 2018 A recent experiment [ Jin , E. ; Science 2017 , 357 , 673 - 676 ] shows that the conductivity of a two-dimensional (2D) sp2-carbon-hybridized pi-conjugated covalent organic framework (sp2-c-COF) can be enhanced by as much as 12 orders of magnitude after iodine oxidation processing. Carbon 124-130 Sp2 transcription factor Homo sapiens 184-187 30495940-0 2018 Highly Green Emissive Nitrogen-Doped Carbon Dots with Excellent Thermal Stability for Bioimaging and Solid-State LED. Carbon 37-43 small integral membrane protein 10 like 2A Homo sapiens 113-116 30563896-8 2018 Derepression of STL1 resulted in enhanced survival and growth of the fungus in the presence of low-nutrient, alternative carbon sources, facilitating virulence in mice. Carbon 121-127 collagen type II alpha 1 chain Homo sapiens 16-20 30524015-0 2018 A fluorescent aptamer/carbon dots based assay for Cytochrome c protein detection as a biomarker of cell apoptosis. Carbon 22-28 cytochrome c, somatic Homo sapiens 50-62 30474366-4 2018 In particular, the detachment of the zwitterionic "coat" at the tumor site resulted in the exposure of abundant peripheral guanidine groups on peptide dendritic carbon dots (CD-D/DOX) owing to the extracellular pH environment (pH 6.8)-induced charge conversion. Carbon 161-167 natriuretic peptide A Homo sapiens 174-178 30519695-5 2018 By comparing the C 1s spectra of non-functional ionic liquids to their functional analogues, a series of difference spectra can be produced to identify exact binding energies of carbon photoemissions, which can be used to improve the C 1s peak fitting of both samples. Carbon 178-184 complement C1s Homo sapiens 17-21 30519695-5 2018 By comparing the C 1s spectra of non-functional ionic liquids to their functional analogues, a series of difference spectra can be produced to identify exact binding energies of carbon photoemissions, which can be used to improve the C 1s peak fitting of both samples. Carbon 178-184 complement C1s Homo sapiens 234-238 31458356-5 2018 Raman spectroscopy and X-ray diffraction verified the amorphous/disordered sp2/sp3 hybrid carbon structure in the produced carbons. Carbon 90-96 Sp2 transcription factor Homo sapiens 75-78 31458356-5 2018 Raman spectroscopy and X-ray diffraction verified the amorphous/disordered sp2/sp3 hybrid carbon structure in the produced carbons. Carbon 90-96 Sp3 transcription factor Homo sapiens 79-82 31458356-5 2018 Raman spectroscopy and X-ray diffraction verified the amorphous/disordered sp2/sp3 hybrid carbon structure in the produced carbons. Carbon 123-130 Sp2 transcription factor Homo sapiens 75-78 31458356-5 2018 Raman spectroscopy and X-ray diffraction verified the amorphous/disordered sp2/sp3 hybrid carbon structure in the produced carbons. Carbon 123-130 Sp3 transcription factor Homo sapiens 79-82 30524015-2 2018 In this work, a simple, rapid, sensitive and selective label-free assay for Cytochrome c (Cyt c) detection is introduced based on an interaction between nucleic acid aptamer biomolecules and surfaces of Carbon Dots (CDs). Carbon 203-209 cytochrome c, somatic Homo sapiens 76-88 30524015-2 2018 In this work, a simple, rapid, sensitive and selective label-free assay for Cytochrome c (Cyt c) detection is introduced based on an interaction between nucleic acid aptamer biomolecules and surfaces of Carbon Dots (CDs). Carbon 203-209 cytochrome c, somatic Homo sapiens 90-95 30422622-0 2018 Enhanced Metabolic Activity of Cytochrome P450 via Carbon Nanocage-Based Photochemical Bionanoreactor. Carbon 51-57 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 31-46 30352875-1 2018 The carbon-fixing activity of enzyme ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) is regulated by Rubisco activase (Rca), a ring-forming ATPase that catalyzes inhibitor release. Carbon 4-10 ribulose bisphosphate carboxylase/oxygenase activase 1, chloroplastic Nicotiana tabacum 111-127 30352875-1 2018 The carbon-fixing activity of enzyme ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) is regulated by Rubisco activase (Rca), a ring-forming ATPase that catalyzes inhibitor release. Carbon 4-10 ribulose bisphosphate carboxylase/oxygenase activase 1, chloroplastic Nicotiana tabacum 129-132 30431259-7 2018 Finally, we show that the exposed interface between sp2 and sp3 carbon layers (i.e. the laser-ablated diamond surface) revealed faster kinetics than the untreated BDD in both ferrocyanide and RuHex mediators, which can be used for electrochemical (bio)sensing. Carbon 64-70 Sp3 transcription factor Homo sapiens 60-63 30558201-0 2018 Acetylcholinesterase Biosensor Based On Mesoporous Hollow Carbon Spheres/Core-Shell Magnetic Nanoparticles-Modified Electrode for the Detection of Organophosphorus Pesticides. Carbon 58-64 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 30274116-5 2018 The nanobiocomposites was characterized using H-NMR and FTIR analysis it was found that secondary alkyl, allylic carbon, monosubstituted alkenes and sp2 hybridized CH bonds of alkenes were involved in binding of cerium and selenium nanoparticles with l-asparaginase for the formation of cerium selenium nanobiocomposite. Carbon 113-119 asparaginase and isoaspartyl peptidase 1 Homo sapiens 251-265 30240135-2 2018 A cobalt@nitrogen-doped carbon (Co@NC) catalyst was prepared from renewable biomass-derived sucrose, harmless melamine, and earth-abundant Co(AcO)2 as the precursor materials by hydrothermal treatment and carbonization. Carbon 24-30 aconitase 2 Homo sapiens 142-147 30347500-1 2018 Carbon bonds (C-bonds) are the highly directional noncovalent interactions between carbonyl-oxygen acceptors and sp3 -hybridized-carbon sigma-hole donors through n sigma* electron delocalization. Carbon 0-6 Sp3 transcription factor Homo sapiens 113-116 30347500-1 2018 Carbon bonds (C-bonds) are the highly directional noncovalent interactions between carbonyl-oxygen acceptors and sp3 -hybridized-carbon sigma-hole donors through n sigma* electron delocalization. Carbon 83-89 Sp3 transcription factor Homo sapiens 113-116 30457342-1 2018 In the present study, a novel synthetic strategy to directly produce versatile 3-acylindoles through Rh(III)-catalyzed C-H activation and annulation cascade of N-phenylamidines with alpha-Cl ketones was developed, in which alpha-Cl ketones serve as unusual one-carbon (sp3) synthons. Carbon 261-267 Sp3 transcription factor Homo sapiens 269-272 30293059-8 2018 Knockdown of ELOVL5 in T-cells and Jurkat cells significantly affected cellular monounsaturated and PUFA profiles and strongly impaired the elongation of 18- and 20-carbon PUFAs. Carbon 165-171 ELOVL fatty acid elongase 5 Homo sapiens 13-19 30293059-9 2018 In conclusion, the induction of proliferation in human T-cells is associated with a significant increase in the capacity to take up and metabolize exogenous PUFAs, and ELOVL5 is responsible for the elongation of 18- and 20-carbon PUFAs in these cells. Carbon 223-229 ELOVL fatty acid elongase 5 Homo sapiens 168-174 30477108-7 2018 These included the BCAA-derived acylcarnitines and sphingomyelins with 16 and 18 carbons. Carbon 81-88 AT-rich interaction domain 4B Homo sapiens 19-23 30199610-3 2018 Herein, we prepare a novel fumaronitrile (FUM) derived covalent triazine framework (FUM-CTF) and activated it by using KOH at different temperatures to obtain the corresponding carbon materials, which were used as supercapacitor electrode materials. Carbon 177-183 nuclear factor I C Homo sapiens 88-91 30358110-3 2018 Herein, the multifunctional polysulfide scavengers based on nitrogen, sulfur co-doped carbon cloth (DCC), which is supported by flower-like MoS2 (1T-2H) decorated with BaMn0.9 Mg0.1 O3 perovskite particle (PrNP) and carbon nanotubes (CNTs), namely, DCC@MoS2 /PrNP/CNTs, are delicately designed and synthesized. Carbon 86-92 prion protein Homo sapiens 206-210 30358110-3 2018 Herein, the multifunctional polysulfide scavengers based on nitrogen, sulfur co-doped carbon cloth (DCC), which is supported by flower-like MoS2 (1T-2H) decorated with BaMn0.9 Mg0.1 O3 perovskite particle (PrNP) and carbon nanotubes (CNTs), namely, DCC@MoS2 /PrNP/CNTs, are delicately designed and synthesized. Carbon 86-92 prion protein Homo sapiens 259-263 30272061-4 2018 Thus, ring-fluorinated furan derivatives were efficiently obtained via allylic sp3 carbon-fluorine bond cleavage. Carbon 83-89 Sp3 transcription factor Homo sapiens 79-82 30252967-4 2018 The flexibility of these "three-atom" hinges was modulated by i) moving from secondary to tertiary amide functional groups and ii) replacing an sp2 amide carbon with an sp3 methylene carbon. Carbon 154-160 Sp2 transcription factor Homo sapiens 144-147 30252967-4 2018 The flexibility of these "three-atom" hinges was modulated by i) moving from secondary to tertiary amide functional groups and ii) replacing an sp2 amide carbon with an sp3 methylene carbon. Carbon 183-189 Sp2 transcription factor Homo sapiens 144-147 30252967-4 2018 The flexibility of these "three-atom" hinges was modulated by i) moving from secondary to tertiary amide functional groups and ii) replacing an sp2 amide carbon with an sp3 methylene carbon. Carbon 183-189 Sp3 transcription factor Homo sapiens 169-172 30362701-2 2018 Carbon fiber paper (CFP) with three-dimensional macroporous structure, excellent corrosion resistance, and high electrical properties is used as the support material to prevent surface passivation during the long-term process of OER. Carbon 0-6 complement factor properdin Homo sapiens 20-23 30383350-6 2018 The unique structure of nanosheets embedded by hollow carbon spheres and N-doping characteristics endow N-HMCS/S with good performance in electrochemical capacitor with high specific capacity (196.5 F g-1) in the three-electrode system and excellent high-rate capability with retention of 61.5% in the two-electrode system. Carbon 54-60 MKKS centrosomal shuttling protein Homo sapiens 106-110 30382261-3 2018 In this work, an approach based upon an empirical potential for the simulation of the Raman spectroscopy of carbon nanomaterials [P. M. Tailor, R. J. Wheatley and N. A. Besley, Carbon, 2017, 113, 299-308] is extended through the addition of a term to describe the van der Waals interaction between layers of sp2 hybridised carbons. Carbon 108-114 Sp2 transcription factor Homo sapiens 308-311 30350696-3 2018 The understanding of the mechanism of Pb(II) adsorption onto AC would allow to optimally design AC-based materials even in the presence of a complex liquid phase. Carbon 61-63 submaxillary gland androgen regulated protein 3B Homo sapiens 38-44 30095189-1 2018 The direct synthesis of organocalcium compounds (heavy Grignard reagents) by the reduction of organyl halides with activated calcium powder succeeded in a straightforward manner for organic bromides and iodides that are bound at sp2 -hybridized carbon atoms. Carbon 245-251 Sp2 transcription factor Homo sapiens 229-232 30350696-1 2018 Activated carbon (AC) is a carbonaceous material broadly applied in filters to remove lead (Pb(II)) from drinking water through adsorption. Carbon 10-16 submaxillary gland androgen regulated protein 3B Homo sapiens 92-98 30350696-9 2018 Overall, this work presents a new set of chemical reactions at the solid-liquid interface between Pb(II) and AC under various conditions of interest for the application of AC or other carbonaceous materials in water treatment. Carbon 109-111 submaxillary gland androgen regulated protein 3B Homo sapiens 98-104 30350696-9 2018 Overall, this work presents a new set of chemical reactions at the solid-liquid interface between Pb(II) and AC under various conditions of interest for the application of AC or other carbonaceous materials in water treatment. Carbon 172-174 submaxillary gland androgen regulated protein 3B Homo sapiens 98-104 30400638-1 2018 A laser system with a wavelength of 1064 nm was used to generate sp2 carbon on the surfaces of nanodiamond particles (NDPs). Carbon 69-75 Sp2 transcription factor Homo sapiens 65-68 30320332-2 2018 Here, we exploit a new droplet sliding mechanism to accelerate the droplet coalescence and collection for highly efficient fog harvesting by coating hydrophilic microfibers with superhydrophobic layers of assembled carbon nanoparticles. Carbon 215-221 zinc finger protein, FOG family member 1 Homo sapiens 123-126 30336057-2 2018 When benziodoxole-activated alkyne was applied as the alkynyl donor, products containing Csp3-Csp bonds involving primary, secondary, and tertiary carbon centers were achieved in up to 97% yields. Carbon 147-153 DnaJ heat shock protein family (Hsp40) member C5 Homo sapiens 89-92 30430612-1 2018 A new method of visualization of lone pairs is proposed using fluorine atoms in fluoroacetylene, trifluoroethylene, and fluoroform (sp, sp2 , and sp3 hybridized carbons) as an example. Carbon 161-168 Sp3 transcription factor Homo sapiens 146-149 29966904-0 2018 Role of surface charge on the interaction between carbon nanodots and human serum albumin. Carbon 50-56 albumin Homo sapiens 76-89 30398206-3 2018 The bond lengths in the central CNOS unit are 1.3444 (19), 1.3556 (18) and 1.6567 (15) A for C-N, C-O and C-S, respectively, and the CNOS and C3N moieties are flat and nearly coplanar with each other, consistent with the C-N bond possessing partial double-bond character. Carbon 32-33 nitric oxide synthase 3 Homo sapiens 133-137 30398206-3 2018 The bond lengths in the central CNOS unit are 1.3444 (19), 1.3556 (18) and 1.6567 (15) A for C-N, C-O and C-S, respectively, and the CNOS and C3N moieties are flat and nearly coplanar with each other, consistent with the C-N bond possessing partial double-bond character. Carbon 93-94 nitric oxide synthase 3 Homo sapiens 32-36 30398206-3 2018 The bond lengths in the central CNOS unit are 1.3444 (19), 1.3556 (18) and 1.6567 (15) A for C-N, C-O and C-S, respectively, and the CNOS and C3N moieties are flat and nearly coplanar with each other, consistent with the C-N bond possessing partial double-bond character. Carbon 93-94 nitric oxide synthase 3 Homo sapiens 32-36 30398206-3 2018 The bond lengths in the central CNOS unit are 1.3444 (19), 1.3556 (18) and 1.6567 (15) A for C-N, C-O and C-S, respectively, and the CNOS and C3N moieties are flat and nearly coplanar with each other, consistent with the C-N bond possessing partial double-bond character. Carbon 93-94 nitric oxide synthase 3 Homo sapiens 32-36 29601805-0 2018 Adsorption of human serum albumin on functionalized single-walled carbon nanotubes reduced cytotoxicity. Carbon 66-72 albumin Homo sapiens 20-33 30172744-0 2018 Acetylcholinesterase biosensor based on functionalized surface of carbon nanotubes for monocrotophos detection. Carbon 66-72 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 30172744-3 2018 In this study, multi-walled carbon nanotubes (MWCNTs) were selected as acetylcholinesterase (AChE) carrier and their surface was modified by introducing different functional groups (-SH, -NH2, -Cl, -OH), hydrophobic alkyl groups (-CH3, -(CH2)2CH3, -(CH2)7CH3, -(CH2)15CH3) and ionic liquids (-IL1, -IL2). Carbon 28-34 acetylcholinesterase (Cartwright blood group) Homo sapiens 71-91 30172744-3 2018 In this study, multi-walled carbon nanotubes (MWCNTs) were selected as acetylcholinesterase (AChE) carrier and their surface was modified by introducing different functional groups (-SH, -NH2, -Cl, -OH), hydrophobic alkyl groups (-CH3, -(CH2)2CH3, -(CH2)7CH3, -(CH2)15CH3) and ionic liquids (-IL1, -IL2). Carbon 28-34 acetylcholinesterase (Cartwright blood group) Homo sapiens 93-97 30316641-4 2018 We report here that the same enzyme that accomplishes this task, the cytochrome P450 monooxygenase CYP-4F2, can also omega-hydroxylate the terminal carbon of alpha-tocopheryl quinone. Carbon 148-154 cytochrome P450 family 4 subfamily F member 2 Homo sapiens 99-106 30071483-3 2018 In this context, the integration of carbon nanotubes (CNT) within osteointegration implants has shown to increase ALP"s mineralization activity in virtue of their surface chemistry and their morphological resemblance to collagen nanofibers. Carbon 36-42 alkaline phosphatase, placental Homo sapiens 114-117 30223321-6 2018 When NaCl concentration increased to 50.0 g L-1, the removal efficiency of total organic carbon (TOC) increased to 79 +- 1%, and the removal rate of polyacrylamide (PAM) raised up to 42.7 +- 0.7 g m-3 d-1. Carbon 89-95 immunoglobulin kappa variable 1-16 Homo sapiens 44-47 30443546-11 2018 Furthermore, we showed that the concurrent dynamic control of ERG20 and ERG9 expression, using ergosterol and carbon source regulation mechanisms, could substantially improve diterpene titer. Carbon 110-116 bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase Saccharomyces cerevisiae S288C 72-76 28825349-4 2018 The results showed that oxygen in the atmosphere was reduced to OH on the GDE, where carbon black catalyzed oxygen reduction to H2O2 and graphene provide Pi-electrons for the following H2O2 decomposition. Carbon 86-92 amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase Homo sapiens 75-78 30342836-1 2018 In this study, commercial activated carbons (GAB and CBP) were successfully used for the removal of two phenoxy acetic class-herbicides, 4-chloro-2-methyl phenoxy acetic acid and 2.4-dichlorophenoxy acetic acid (MCPA and 2.4-D) from aqueous solution. Carbon 36-43 CREB binding protein Homo sapiens 53-56 30342836-3 2018 The results suggest that the microporous properties of GAB activated carbon enhanced the adsorption capacity, in comparison to CBP carbon. Carbon 131-137 CREB binding protein Homo sapiens 127-130 30388734-8 2018 A detailed analysis of X-ray photoelectron spectra reveals that the sp2 hybrid state is the main chemical state in carbon. Carbon 115-121 Sp2 transcription factor Homo sapiens 68-71 30317456-5 2018 Two LOX classes are recognized, the 9- and 13-LOXs that oxygenate lipids at the 9th and 13th carbon atom, respectively. Carbon 93-99 probable linoleate 9S-lipoxygenase 5 Capsicum annuum 4-7 30337711-1 2018 Carbon-carbon bonds, including those between sp3-hybridized carbon atoms (alkyl-alkyl bonds), typically comprise much of the framework of organic molecules. Carbon 0-6 Sp3 transcription factor Homo sapiens 45-48 30337711-1 2018 Carbon-carbon bonds, including those between sp3-hybridized carbon atoms (alkyl-alkyl bonds), typically comprise much of the framework of organic molecules. Carbon 7-13 Sp3 transcription factor Homo sapiens 45-48 30337711-1 2018 Carbon-carbon bonds, including those between sp3-hybridized carbon atoms (alkyl-alkyl bonds), typically comprise much of the framework of organic molecules. Carbon 60-66 Sp3 transcription factor Homo sapiens 45-48 30337711-2 2018 In the case of sp3-hybridized carbon, the carbon can be stereogenic and the particular stereochemistry can have implications for structure and function1-3. Carbon 30-36 Sp3 transcription factor Homo sapiens 15-18 30337711-2 2018 In the case of sp3-hybridized carbon, the carbon can be stereogenic and the particular stereochemistry can have implications for structure and function1-3. Carbon 42-48 Sp3 transcription factor Homo sapiens 15-18 30086949-6 2018 The as-synthesized carbon dots were used for the detection of NO2-, NO3- and Fe3+ in food matrices after proper pretreatment, concluding that the multi-probe fluorescence system may potentially be implemented in food control. Carbon 19-25 NBL1, DAN family BMP antagonist Homo sapiens 68-71 30427797-7 2018 With post-DN and an external carbon source, 0.68 to 2.2 g NO3-Neq/m2-d removal rates were obtained. Carbon 29-35 NBL1, DAN family BMP antagonist Homo sapiens 58-61 30059906-7 2018 However, the CDOM265 bound to Pb(II) prior to aryl C-H and polysaccharide C-OH groups at higher pH and IS (6.0 and 0.1 M, respectively), showing that the binding sequences were highly dependent on solution chemistry. Carbon 13-14 submaxillary gland androgen regulated protein 3B Homo sapiens 30-36 30338975-3 2018 Here, a novel and stable sodium titanate/carbon-black phosphorus (NTO/C-BP) hybrids are first fabricated as a promising anode material for advanced sodium-ion batteries. Carbon 41-47 CREB binding protein Homo sapiens 70-74 30165322-7 2018 Full-scale testing in a biologically activated membrane bioreactor (BAMBi) system treating 75 L/day of nutrient-supplemented hand washing water showed that long-term operation (100 days) can deliver effective carbon removal (95%) without detrimental fouling or other disruptions caused by cell growth. Carbon 209-215 BMP and activin membrane bound inhibitor Homo sapiens 68-73 30005407-7 2018 Carbon ion beams irradiation up-regulated the expression levels of C-REPEAT BINDING FACTORS (CBFs), INDUCER OF CBF EXPRESSION 1 (ICE1), ICE2, CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 3 (CAMTA3) and cold-regulated COR genes, in response to cold stress. Carbon 0-6 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 100-127 30177779-1 2018 The introduction of sp3 defects into single-walled carbon nanotubes through covalent functionalization can generate new light-emitting states and thus dramatically expand their optical functionality. Carbon 51-57 Sp3 transcription factor Homo sapiens 20-23 30005407-7 2018 Carbon ion beams irradiation up-regulated the expression levels of C-REPEAT BINDING FACTORS (CBFs), INDUCER OF CBF EXPRESSION 1 (ICE1), ICE2, CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 3 (CAMTA3) and cold-regulated COR genes, in response to cold stress. Carbon 0-6 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 129-133 30384681-5 2018 We provide both classical and quantum pictures of intermode couplings and show that the SN2 mechanism is favored by the coupling of a C-Cl bend involving the Cl- projectile with the CH3 rocking motion of the target molecule. Carbon 134-135 solute carrier family 38 member 5 Homo sapiens 88-91 30374844-6 2018 RESULTS: Results show that TERF1 represses the genes encoding the photosynthetic apparatus at both transcriptional and translational level, but the genes involved in carbon fixation are significantly induced by TERF1. Carbon 166-172 ethylene-responsive transcription factor 1 Solanum lycopersicum 211-216 30306575-6 2018 The transformation of strained sp2 -carbon atom in unperturbed C60 -fullerene to nonconstrained tetrahedral sp3 -type in functionalized derivatives was found to be the driving force for the formation of its functionalized cations. Carbon 36-42 Sp2 transcription factor Homo sapiens 31-34 30306575-6 2018 The transformation of strained sp2 -carbon atom in unperturbed C60 -fullerene to nonconstrained tetrahedral sp3 -type in functionalized derivatives was found to be the driving force for the formation of its functionalized cations. Carbon 36-42 Sp3 transcription factor Homo sapiens 108-111 31458078-8 2018 The comparison of the energy contributions to the binding between C60 or Gd@C60 and lysozyme suggests that, although shape complementarity remains the driving force of the binding, the presence of electron transfer from the gadolinium atom to the carbon cage induces a charge distribution on the fullerene cage that strongly affects its interaction with the protein. Carbon 247-253 lysozyme Homo sapiens 84-92 29890394-0 2018 Carbon nanofiber-based multiplexed immunosensor for the detection of survival motor neuron 1, cystic fibrosis transmembrane conductance regulator and Duchenne Muscular Dystrophy proteins. Carbon 0-6 CF transmembrane conductance regulator Homo sapiens 94-145 30303391-0 2018 Stereocontrolled Nucleophilic Fluorination at the Tertiary sp3-Carbon Center for Enantiopure Synthesis of 3-Fluorooxindoles. Carbon 63-69 Sp3 transcription factor Homo sapiens 59-62 30303391-1 2018 The first asymmetric nucleophilic fluorination at the sp3-tertiary carbon center has been developed using inexpensive tetrabutylammonium fluoride (TBAF) without any metal/catalyst for the synthesis of 3-fluoro-3-substituted oxindoles with excellent enantioselectivity (ee up to >99%). Carbon 67-73 Sp3 transcription factor Homo sapiens 54-57 30340409-3 2018 In this work, an electrochemical impedance spectroscopy (EIS) method adjustable by anionic porphyrin for HER2 gene detection has been proposed, based on the impedance difference between multi-walled carbon nanotubes (MWCNTs) and DNA. Carbon 199-205 erb-b2 receptor tyrosine kinase 2 Homo sapiens 105-109 29890394-4 2018 Here, we report the development of a disposable carbon nanofiber (CNF)-based electrochemical immunosensor for simultaneous detection of survival motor neuron 1 (SMN1), cystic fibrosis transmembrane conductance regulator (CFTR) and DMD proteins. Carbon 48-54 CF transmembrane conductance regulator Homo sapiens 221-225 30031919-2 2018 In this work, estimation of pure gases (CH4, N2, CO2, H2, C2H4) adsorption on activated carbon (AC) and CO2, CH4, N2 on Zeolite-5A adsorbent were studied by developing four different computing techniques, namely MLP-ANN, ANFIS, LSSVM, and PSO-ANFIS for a broad range of experimental data found in the literature. Carbon 88-94 mucin 2, oligomeric mucus/gel-forming Homo sapiens 212-215 30410620-3 2018 Its CDI-activated acylimidazole derivative was then converted to a beta-ketoester containing a two carbon atom-elongated side chain than that of the starting material. Carbon 99-105 amyloid beta precursor protein Homo sapiens 65-71 30142597-6 2018 In addition, simultaneous hydroxyl substitution of the aromatic ring and the conjugated double carbon bonds of ADDA (m/z = 1027.5) are reported for the first time. Carbon 95-101 adducin 1 Homo sapiens 111-115 29803050-7 2018 It showed that size distributions of high-temperature carbon fraction such as OC4, OP and EC1 were almost unimodal during all seasons as well as SO42- and NH4+, in contrast, that of lower temperature carbon fraction (OC1-OC3), Mg2+, and Ca2+ appear like bimodal. Carbon 200-206 one cut homeobox 3 Homo sapiens 217-224 30315312-4 2018 The latter is determined by growth kinetics of TiC layer based on carbon diffusion process. Carbon 66-72 pleckstrin and Sec7 domain containing 4 Homo sapiens 47-50 29685705-0 2018 Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways. Carbon 43-49 protein kinase, DNA-activated, catalytic subunit Homo sapiens 70-78 30003607-1 2018 Diacylglycerol acyltransferase 1 (DGAT1) catalyzes the final and committed step in the Kennedy pathway for triacylglycerol (TAG) biosynthesis and, as such, elucidating its mode of regulation is critical to understand the fundamental aspects of carbon metabolism in oleaginous crops. Carbon 244-250 diacylglycerol O-acyltransferase 1-like Brassica napus 0-32 30003607-1 2018 Diacylglycerol acyltransferase 1 (DGAT1) catalyzes the final and committed step in the Kennedy pathway for triacylglycerol (TAG) biosynthesis and, as such, elucidating its mode of regulation is critical to understand the fundamental aspects of carbon metabolism in oleaginous crops. Carbon 244-250 diacylglycerol O-acyltransferase 1-like Brassica napus 34-39 30104058-7 2018 TGA and ATR-FTIR showed an increase in the percent carbon loss along the length of the column, indicating that there was an increase in the C18 ligand from the front to the end of the column. Carbon 51-57 Bardet-Biedl syndrome 9 Homo sapiens 140-143 30188117-0 2018 P-Glycoprotein-Targeted Photothermal Therapy of Drug-Resistant Cancer Cells Using Antibody-Conjugated Carbon Nanotubes. Carbon 102-108 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 30188117-2 2018 As conventional approaches using small-molecule inhibitors failed in clinical development because of the lack of cancer specificity, we develop Pgp-targeted carbon nanotubes to achieve highly cancer-specific therapy through combining antibody-based cancer targeting and locoregional tumor ablation with photothermal therapy. Carbon 157-163 ATP binding cassette subfamily B member 1 Homo sapiens 144-147 30333839-4 2018 As the XPT is also capable of transporting triose phosphates, it might as well support the triose phosphate PT (TPT) in exporting photoassimilates from the chloroplast in the light ("day path of carbon") and hence in supplying the whole plant with carbohydrates. Carbon 195-201 Glucose-6-phosphate/phosphate translocator-like protein Arabidopsis thaliana 112-115 30102471-1 2018 An intramolecular 1,2-boryl-anion migration from boron to carbon has been achieved by selective activation of the pi system in [(vinyl)B2 Pin2 )]- using "soft" BR3 electrophiles (BR3 =BPh3 or 9-aryl-BBN). Carbon 58-64 telomeric repeat binding factor 1 Homo sapiens 138-142 29920445-2 2018 After 155 d of operation, the NO3- as the PN-Anammox byproduct was almost treated with biodegradable organic carbon in raw wastewater in a pre-denitrification reactor by external recycling system. Carbon 109-115 NBL1, DAN family BMP antagonist Homo sapiens 30-33 29685705-8 2018 RESULTS: Genistein sensitized DNA-PKcs proficient GBM cells to high-LET carbon ions via delaying the clearance of gamma-H2AX foci. Carbon 72-78 protein kinase, DNA-activated, catalytic subunit Homo sapiens 30-38 29685705-11 2018 CONCLUSION: Our study demonstrated that genistein holds promise as a radiosensitizer for enhancing the efficacy of carbon ion radiotherapy against DNA-PKcs proficient GBM via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways. Carbon 115-121 protein kinase, DNA-activated, catalytic subunit Homo sapiens 147-155 30169018-0 2018 A Fluorescent Carbon Nanotube Sensor Detects the Metastatic Prostate Cancer Biomarker uPA. Carbon 14-20 plasminogen activator, urokinase Homo sapiens 86-89 30029391-5 2018 This proposed detector was further successfully applied to the discrimination of different concentrations of CS2 in air samples and two types of isomers (functional group isomer and carbon-chain isomer). Carbon 182-188 chorionic somatomammotropin hormone 2 Homo sapiens 109-112 30169018-3 2018 We used the unique fluorescent characteristics of single-walled carbon nanotubes (SWCNT) to engineer an optical sensor that responds to uPA via optical bandgap modulation in complex protein environments. Carbon 64-70 plasminogen activator, urokinase Homo sapiens 136-139 29939201-8 2018 The antitumor effects of an MDD/RT approach were due to effects on one-carbon metabolism, resulting in impaired methionine biotransformation via downregulation of Mat2a, which encodes methionine adenosyltransferase 2A. Carbon 71-77 methionine adenosyltransferase II, alpha Mus musculus 163-168 29972377-7 2018 A mixed sp2/sp3 carbon hybridization in the NA interface region suggests that the interfacial carbon atoms have lost their tetrahedral SiC coordination. Carbon 16-22 Sp3 transcription factor Homo sapiens 12-15 29972377-7 2018 A mixed sp2/sp3 carbon hybridization in the NA interface region suggests that the interfacial carbon atoms have lost their tetrahedral SiC coordination. Carbon 94-100 Sp2 transcription factor Homo sapiens 8-11 29972377-7 2018 A mixed sp2/sp3 carbon hybridization in the NA interface region suggests that the interfacial carbon atoms have lost their tetrahedral SiC coordination. Carbon 94-100 Sp3 transcription factor Homo sapiens 12-15 29987303-0 2018 Impact of PEG additives and pore rim functionalization on water transport through sub-1 nm carbon nanotube porins. Carbon 91-97 SUB1 regulator of transcription Homo sapiens 82-87 29987303-2 2018 In the past, sub-1 nm diameter carbon nanotube porins (CNTPs) embedded in a lipid membrane matrix demonstrated extremely high water permeabilities and strong ion selectivities. Carbon 31-37 SUB1 regulator of transcription Homo sapiens 13-18 30169031-2 2018 Herein, we present the new homologous 2D series (NH3C mH2 mNH3)(CH3NH3) n-1Pb nI3 n+1 ( m = 4-9; n = 1-4), where m represents the carbon-chain number and n equals layer-thickness number. Carbon 130-136 histocompatibility-2, MHC Mus musculus 54-57 30118206-0 2018 Self-Inhibitory Electron Transfer of the Co(III)/Co(II)-Complex Redox Couple at Pristine Carbon Electrode. Carbon 89-95 mitochondrially encoded cytochrome c oxidase III Homo sapiens 41-48 30129757-3 2018 The key reaction is the introduction of an sp3 carbon alkyl chain bearing a leaving group at the meso-position of the CD-ring component by using the corresponding Grignard reagents in the presence of LiCl. Carbon 47-53 Sp3 transcription factor Homo sapiens 43-46 30179495-2 2018 The reaction constructs dual distinct C-N bonds via sp2/sp3 C-H activation and rhodium nitrene insertion. Carbon 38-39 Sp2 transcription factor Homo sapiens 52-55 30179495-2 2018 The reaction constructs dual distinct C-N bonds via sp2/sp3 C-H activation and rhodium nitrene insertion. Carbon 38-39 Sp3 transcription factor Homo sapiens 56-59 30199260-3 2018 A proline sulfonamide-catalyzed Yamada-Otani reaction was used to access the highly functionalized cyclohexane A ring core, including the C10 all-carbon quaternary stereocenter. Carbon 146-152 homeobox C10 Homo sapiens 138-141 30118206-0 2018 Self-Inhibitory Electron Transfer of the Co(III)/Co(II)-Complex Redox Couple at Pristine Carbon Electrode. Carbon 89-95 mitochondrially encoded cytochrome c oxidase II Homo sapiens 41-46 30149914-2 2018 The present study elucidated the involvement of pro-inflammatory cytokines, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in carboxylated multi-walled carbon nanotubes (MWCNTs)-induced hepatotoxicity. Carbon 173-179 nitric oxide synthase 2 Rattus norvegicus 105-136 30149914-2 2018 The present study elucidated the involvement of pro-inflammatory cytokines, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in carboxylated multi-walled carbon nanotubes (MWCNTs)-induced hepatotoxicity. Carbon 173-179 nitric oxide synthase 2 Rattus norvegicus 138-142 30118206-3 2018 Herein, we employ nanoscale scanning electrochemical microscopy (SECM) and cyclic voltammetry to gain new insights into the interplay between heterogeneous ET and adsorption of a Co(III)/Co(II)-complex redox couple at the contamination-free surface of electron-beam-deposited carbon (eC). Carbon 276-282 mitochondrially encoded cytochrome c oxidase III Homo sapiens 179-186 30118206-3 2018 Herein, we employ nanoscale scanning electrochemical microscopy (SECM) and cyclic voltammetry to gain new insights into the interplay between heterogeneous ET and adsorption of a Co(III)/Co(II)-complex redox couple at the contamination-free surface of electron-beam-deposited carbon (eC). Carbon 276-282 mitochondrially encoded cytochrome c oxidase II Homo sapiens 179-184 30137083-1 2018 Surface-confined host-guest chemistry at the air/solid interface is used for trapping a functionalized 3D Zn-phthalocyanine complex into a 2D porous supramolecular template allowing the large area functionalization of an sp2-hybridized carbon-based substrate as evidenced by STM, resonance Raman spectroscopy, and water contact angle measurements. Carbon 236-242 Sp2 transcription factor Homo sapiens 221-224 30203255-4 2018 However, MWCNTs and MWCNTs-added carbon composites (e.g., CNP/MWCNT, MWCNT/GF, CNP/MWCNT/GF) were found to enhance the charge transfer from CE to liquid electrolyte due to the formation of highly networked structures with high specific surface area. Carbon 33-39 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 58-61 30203255-4 2018 However, MWCNTs and MWCNTs-added carbon composites (e.g., CNP/MWCNT, MWCNT/GF, CNP/MWCNT/GF) were found to enhance the charge transfer from CE to liquid electrolyte due to the formation of highly networked structures with high specific surface area. Carbon 33-39 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 79-82 30085672-0 2018 Exciton Self-Trapping in sp2 Carbon Nanostructures Induced by Edge Ether Groups. Carbon 29-35 Sp2 transcription factor Homo sapiens 25-28 29923558-0 2018 Ultra-low friction mechanism of highly sp3-hybridized amorphous carbon controlled by interfacial molecule adsorption. Carbon 64-70 Sp3 transcription factor Homo sapiens 39-42 29923558-1 2018 The friction behaviors of highly sp3-hybridized carbon films, including ultra-nanocrystalline diamond and diamond-like carbon materials, strongly depend on the atmosphere. Carbon 48-54 Sp3 transcription factor Homo sapiens 33-36 29923558-1 2018 The friction behaviors of highly sp3-hybridized carbon films, including ultra-nanocrystalline diamond and diamond-like carbon materials, strongly depend on the atmosphere. Carbon 119-125 Sp3 transcription factor Homo sapiens 33-36 29923558-3 2018 By means of density functional theory calculations, this study aims to fill a knowledge gap about the correlation between the evolving contact quality induced by the adsorption of molecules, and the friction behavior of highly sp3-bonded carbons. Carbon 238-245 Sp3 transcription factor Homo sapiens 227-230 30194494-1 2018 The authors describe a method for electrochemical determination of the breast cancer biomarker alpha-lactalbumin (alpha-LA) using disposable screen-printed carbon electrodes (SPCEs). Carbon 156-162 lactalbumin alpha Homo sapiens 95-112 30194494-1 2018 The authors describe a method for electrochemical determination of the breast cancer biomarker alpha-lactalbumin (alpha-LA) using disposable screen-printed carbon electrodes (SPCEs). Carbon 156-162 lactalbumin alpha Homo sapiens 114-122 30190578-1 2018 The grain boundaries in superconducting MgB2 are known to form effective magnetic flux pinning sites and, consequently, bulk MgB2 containing a fine-grain microstructure fabricated from nanoscale Mg and B precursor powders exhibits good magnetic field-trapping performance below 20 K. We report here that the trapped field of MgB2 bulk superconductors fabricated by an infiltration and growth process to yield a dense, pore-free microstructure, can be enhanced significantly by carbon-doping, which increases intra-band scattering within the superconducting grains. Carbon 477-483 secretoglobin family 2A member 1 Homo sapiens 40-44 30190578-1 2018 The grain boundaries in superconducting MgB2 are known to form effective magnetic flux pinning sites and, consequently, bulk MgB2 containing a fine-grain microstructure fabricated from nanoscale Mg and B precursor powders exhibits good magnetic field-trapping performance below 20 K. We report here that the trapped field of MgB2 bulk superconductors fabricated by an infiltration and growth process to yield a dense, pore-free microstructure, can be enhanced significantly by carbon-doping, which increases intra-band scattering within the superconducting grains. Carbon 477-483 secretoglobin family 2A member 1 Homo sapiens 125-129 30190578-1 2018 The grain boundaries in superconducting MgB2 are known to form effective magnetic flux pinning sites and, consequently, bulk MgB2 containing a fine-grain microstructure fabricated from nanoscale Mg and B precursor powders exhibits good magnetic field-trapping performance below 20 K. We report here that the trapped field of MgB2 bulk superconductors fabricated by an infiltration and growth process to yield a dense, pore-free microstructure, can be enhanced significantly by carbon-doping, which increases intra-band scattering within the superconducting grains. Carbon 477-483 secretoglobin family 2A member 1 Homo sapiens 125-129 29980580-1 2018 Imrecoxib is a typical cyclooxygenase-2 inhibitor and the benzylic carbon motif is its major site of oxidative metabolism, producing a hydroxymethyl metabolite (M1) and a carboxylic acid metabolite (M2). Carbon 67-73 prostaglandin-endoperoxide synthase 2 Homo sapiens 23-39 29931794-7 2018 A Rosetta docking model of CYP7B1 suggested that these substrates" D-ring hydroxy groups might prevent them from binding in the same way as the native substrates, bringing different carbon atoms close to the active ferryl oxygen atom. Carbon 182-188 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 27-33 30132992-2 2018 Here, it is reported that agglomerates of large ruthenium phosphide (RuP) particles (L-RP, 32 nm) show outstanding HER performance in pH-universal electrolytes, which particularly demonstrates a surprisingly higher intrinsic activity and durability than small nanoparticles of RuP (S-RP, 3 nm) or metallic Ru on carbon supports. Carbon 314-320 ribosomal protein SA Homo sapiens 85-89 29923353-4 2018 The combined carbon transport via various pathways through inland aquatic ecosystems of Alaska was estimated to be 41.3 Tg C/yr (17% of terrestrial NPP). Carbon 13-19 transglutaminase 2 Homo sapiens 120-124 29923353-5 2018 During the projection period (2010-2099), carbon storage of terrestrial ecosystems of Alaska was projected to increase (22.5-70.0 Tg C/yr), primarily because of NPP increases of 10-30% associated with responses to rising atmospheric CO2 , increased nitrogen cycling, and longer growing seasons. Carbon 42-48 transglutaminase 2 Homo sapiens 130-134 30089209-3 2018 In this work, we prepared conjugates of carbon nanoparticles (CNP) with DNA aptamers using streptavidin-biotin reaction. Carbon 40-46 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 62-65 30136862-5 2018 Drawbacks associated with graphene-based materials for biomedical applications include defect-free graphene formation and heteroatom contamination during synthesis process; reduced availability of sp2 hybridized carbon centers due to serum proteins masking; and poor availability of data pertaining to in vivo clearance of graphene-based formulations. Carbon 212-218 Sp2 transcription factor Homo sapiens 197-200 30042213-9 2018 The results are discussed in terms of how AOX contributes to TPU capacity and the maintenance of chloroplast ATP synthase activity at ECO2 Overall, the evidence suggests that AOX respiration is needed to maintain both the carbon and energy balance in photosynthetic tissues during growth at ECO2. Carbon 222-228 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 42-45 29978316-1 2018 A novel ion-imprinted polymer (IIP) toward Pb(II) recognition was synthesized on the surface of magnetic multi-walled carbon nanotubes (magnetic MWCNTs). Carbon 118-124 submaxillary gland androgen regulated protein 3B Homo sapiens 43-49 29956732-0 2018 Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3. Carbon 14-20 sirtuin 3 Homo sapiens 131-136 29905794-6 2018 Consequently, prionization of Swi1 leads to a variety of phenotypes including poor growth on non-glucose carbon sources and abolishment of multicellular features-with implications on characterization of [SWI+] as being detrimental or beneficial to yeast. Carbon 105-111 Swi1p Saccharomyces cerevisiae S288C 30-34 29677815-5 2018 The enhanced electrochemical performance of S100 could be attributed to the configuration of the SnO2 particles infiltrating the carbon-coated hollow channels, which accommodated large volume changes during (de)lithiation. Carbon 129-135 S100 calcium binding protein A1 Homo sapiens 44-48 30258135-1 2018 There is evidence to suggest that increasing the level of saturation (that is, the number of sp3-hybridized carbon atoms) of small molecules can increase their likelihood of success in the drug discovery pipeline1. Carbon 108-114 Sp3 transcription factor Homo sapiens 93-96 29673051-1 2018 The ability of leaves to absorb fog water can positively contribute to the water and carbon balance of plants in montane ecosystems, especially in periods of soil water deficit. Carbon 85-91 zinc finger protein, FOG family member 1 Homo sapiens 32-35 30042213-9 2018 The results are discussed in terms of how AOX contributes to TPU capacity and the maintenance of chloroplast ATP synthase activity at ECO2 Overall, the evidence suggests that AOX respiration is needed to maintain both the carbon and energy balance in photosynthetic tissues during growth at ECO2. Carbon 222-228 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 175-178 30152578-3 2018 Thus, an effective catalytic conversion from sp3 to sp2 carbon occurs, enabling simultaneously formation of pores with catalyzed graphitic structures. Carbon 56-62 Sp3 transcription factor Homo sapiens 45-48 29788500-0 2018 Microvascular Dysfunction Following Multiwalled Carbon Nanotube Exposure Is Mediated by Thrombospondin-1 Receptor CD47. Carbon 48-54 thrombospondin 1 Homo sapiens 88-104 30152578-3 2018 Thus, an effective catalytic conversion from sp3 to sp2 carbon occurs, enabling simultaneously formation of pores with catalyzed graphitic structures. Carbon 56-62 Sp2 transcription factor Homo sapiens 52-55 30167785-0 2018 A glassy carbon electrode modified with a bismuth film and laser etched graphene for simultaneous voltammetric sensing of Cd(II) and Pb(II). Carbon 9-15 submaxillary gland androgen regulated protein 3B Homo sapiens 122-139 29715643-5 2018 The result is shown to be caused by electrochemical advanced oxidation processes (EAOP) and regeneration of sp2-surface-bonded carbon functional groups that serve the dual purpose of catalysts and adsorption sites of oxidant intermediates. Carbon 127-133 Sp2 transcription factor Homo sapiens 108-111 30088413-3 2018 We generalize a rigorous algorithm for the formation of all possible classes of these superstructures: the structural parameters employed to design such carbon nanocomposites include the commensurate bilayer"s twist angle, the stacking type of the nanodomains where the interlayer bonds are formed, the interlayer bond pattern, and the interlayer C-C bond density that is proportional to the concentration of sp3-hybridized interlayer-bonded C atoms. Carbon 153-159 Sp3 transcription factor Homo sapiens 409-412 30024720-3 2018 It reveals that the ceramics pyrolyzed from the benzene ring-containing preceramic precursors have a higher carbon content and a larger number of sp2 carbons and generate crystalline carbons (graphitic carbons and tubular carbons) in situ, which lead to excellent EM wave-absorbing properties. Carbon 150-157 Sp2 transcription factor Homo sapiens 146-149 29995379-0 2018 Solvent- and Wavelength-Dependent Photoluminescence Relaxation Dynamics of Carbon Nanotube sp3 Defect States. Carbon 75-81 Sp3 transcription factor Homo sapiens 91-94 29995379-1 2018 Photoluminescent sp3 defect states introduced to single wall carbon nanotubes (SWCNTs) through low-level covalent functionalization create new photophysical behaviors and functionality as a result of defect sites acting as exciton traps. Carbon 61-67 Sp3 transcription factor Homo sapiens 17-20 30016072-5 2018 Correspondingly, we convert the sp3-hybridized state to an sp2-hybridized state of carbon atoms, i. e., from an alkyl group to an alkenyl one. Carbon 83-89 Sp3 transcription factor Homo sapiens 32-35 30016072-5 2018 Correspondingly, we convert the sp3-hybridized state to an sp2-hybridized state of carbon atoms, i. e., from an alkyl group to an alkenyl one. Carbon 83-89 Sp2 transcription factor Homo sapiens 59-62 31459117-0 2018 Nitrogen-Doped Nanoporous Carbon Nanospheroids for Selective Dye Adsorption and Pb(II) Ion Removal from Waste Water. Carbon 26-32 submaxillary gland androgen regulated protein 3B Homo sapiens 80-86 31459117-4 2018 The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively. Carbon 112-113 Sp2 transcription factor Homo sapiens 107-110 31459117-4 2018 The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively. Carbon 112-113 Sp3 transcription factor Homo sapiens 124-127 31459117-4 2018 The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively. Carbon 116-117 Sp2 transcription factor Homo sapiens 107-110 31459117-4 2018 The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively. Carbon 116-117 Sp3 transcription factor Homo sapiens 124-127 31459117-4 2018 The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively. Carbon 116-117 Sp2 transcription factor Homo sapiens 107-110 31459117-4 2018 The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively. Carbon 116-117 Sp3 transcription factor Homo sapiens 124-127 31459117-4 2018 The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively. Carbon 161-168 Sp2 transcription factor Homo sapiens 107-110 31459117-4 2018 The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively. Carbon 161-168 Sp3 transcription factor Homo sapiens 124-127 30109931-1 2018 Since the discovery of buckminsterfullerene over 30 years ago, sp2-hybridised carbon nanomaterials (including fullerenes, carbon nanotubes, and graphene) have stimulated new science and technology across a huge range of fields. Carbon 78-84 Sp2 transcription factor Homo sapiens 63-66 30109931-1 2018 Since the discovery of buckminsterfullerene over 30 years ago, sp2-hybridised carbon nanomaterials (including fullerenes, carbon nanotubes, and graphene) have stimulated new science and technology across a huge range of fields. Carbon 122-128 Sp2 transcription factor Homo sapiens 63-66 29752881-1 2018 The first photoinduced carbon(sp2 )-heteroatom bond forming reaction by a rare-earth-metal photoreductant, a Miyaura borylation, has been achieved. Carbon 23-29 Sp2 transcription factor Homo sapiens 30-33 30147354-6 2018 The estimated glomerular filtration rate (eGFR) by the formula developed by Japanese Society of Nephrology (in mL/min/1.73 m2) decreased: C group (from 28.3+-13.6 to 23.0+-12.3, p=0.09), T group (from 22.7+-12.4 to 19.4+-12.2, p=0.18), but both did not reach significance. Carbon 138-139 CD59 molecule (CD59 blood group) Homo sapiens 114-119 30059218-2 2018 Alkane carbon sp3 orbitals are represented by edge weighted tetrahedral stellate graphs connected to hydrogen orbitals. Carbon 7-13 Sp3 transcription factor Homo sapiens 14-17 29734035-1 2018 This paper reports the development and performance of an electrochemical immunosensor using magnetic multiwalled carbon nanotubes (m-MWCNTs) as nanocarrier tags for the determination of human fetuin A (HFA), a relevant biomarker of obesity, insulin resistance, and type-2 diabetes as well as for pancreatic and liver cancers and inflammatory processes. Carbon 113-119 alpha 2-HS glycoprotein Homo sapiens 192-200 29753165-0 2018 Diagnosis of EGFR exon21 L858R point mutation as lung cancer biomarker by electrochemical DNA biosensor based on reduced graphene oxide /functionalized ordered mesoporous carbon/Ni-oxytetracycline metallopolymer nanoparticles modified pencil graphite electrode. Carbon 171-177 epidermal growth factor receptor Homo sapiens 13-17 29753165-1 2018 In this present work we made a novel, fast, selective and sensitive electrochemical genobiosensor to detection of EGFR exon 21 point mutation based on two step electropolymerization of Ni(II)-oxytetracycline conducting metallopolymer nanoparticles (Ni-OTC NPs) on the surface of pencil graphite electrode (PGE) which was modified by reduced graphene oxide/carboxyl functionalized ordered mesoporous carbon (rGO/f-OMC) nanocomposite. Carbon 399-405 epidermal growth factor receptor Homo sapiens 114-118 30083668-5 2018 Our results show that the presence of the hydrogen atom on the Pt catalyst can efficiently induce the H-diffusion process through the C-C surface, and the Pt-H bond significantly facilitates the H-migration from C-H bonds near to the active Pt catalyst to the adjacent carbon atom with an energy barrier <0.5 eV under ambient conditions. Carbon 269-275 parathyroid hormone Homo sapiens 155-159 29998700-8 2018 RDA analysis showed that soil carbon and nitrogen contents had significant positive relationships with the activities of BG and NAG in the 0-20 cm soil profiles, however, negative relationships were observed in the 20-40 cm soil profiles. Carbon 30-36 N-acetyl-alpha-glucosaminidase Homo sapiens 128-131 31459037-0 2018 Electrochemical Detection of pH-Responsive Grafted Catechol and Immobilized Cytochrome c onto Lipid Deposit-Modified Glassy Carbon Surface. Carbon 124-130 cytochrome c, somatic Homo sapiens 76-88 30097644-1 2018 The abundance of organic carbon (OC) in vegetation and soils (~2,600 PgC) compared to carbon in the atmosphere (~830 PgC) highlights the importance of terrestrial OC in global carbon budgets. Carbon 25-31 progastricsin Homo sapiens 69-72 31459037-5 2018 Cytochrome c immobilization into the optimized supported lipid deposit is efficiently achieved by cyclic voltammetry (10 cycles) recorded at the modified glassy carbon electrode in a cytochrome c solution. Carbon 161-167 cytochrome c, somatic Homo sapiens 0-12 31459037-6 2018 The pH-dependent redox response of the grafted catechol and that of the immobilized cytochrome c are finally detected at the same lipid-modified glassy carbon electrode without alteration of their structure and electrochemical properties in the pH range 5-9. Carbon 152-158 cytochrome c, somatic Homo sapiens 84-96 29853604-6 2018 Our data identify the helicase/NFkappaB/TNFalpha/COX2 axis as the key suppressive pathway of dsRNA signaling in human TME and suggest that selective targeting of TLR3 or elimination of NFkappaB/TNFalpha/COX2-driven suppression may allow for selective enhancement of type-1 immunity.Significance: This study characterizes two different poly-I:C-induced signaling pathways in their induction of immunostimulatory and suppressive factors and suggests improved ways to reprogram the TME to enhance the antitumor efficacy of immunotherapies. Carbon 49-50 nuclear factor kappa B subunit 1 Homo sapiens 31-39 29954179-1 2018 A one-dimensional (1D) sp3 carbon nanomaterial with high lateral packing order, known as carbon nanothreads, has recently been synthesized by slowly compressing and decompressing crystalline solid benzene at high pressure. Carbon 27-33 Sp3 transcription factor Homo sapiens 23-26 29954179-1 2018 A one-dimensional (1D) sp3 carbon nanomaterial with high lateral packing order, known as carbon nanothreads, has recently been synthesized by slowly compressing and decompressing crystalline solid benzene at high pressure. Carbon 89-95 Sp3 transcription factor Homo sapiens 23-26 30027966-4 2018 Therefore, the nitrogen doping in the sp2 carbon network can be controlled by the flow rate of the C/N feedstock. Carbon 42-48 Sp2 transcription factor Homo sapiens 38-41 29658165-1 2018 This study reports on the electropolymerization of a low toxic and biocompatible nanopolymer with entitle poly arginine-graphene quantum dots-chitosan (PARG-GQDs-CS) as a novel strategy for surface modification of glassy carbon surface and preparation of a new interface for measurement of malondialdehyde (MDA) in exhaled breath condensate. Carbon 221-227 poly(ADP-ribose) glycohydrolase Homo sapiens 152-156 29588286-5 2018 Among the 2,086 participants without diabetes, higher levels of plasma ceramides carrying the fatty acids 16:0 (16 carbons, 0 double bond), 18:0, 20:0, or 22:0 were associated with higher plasma insulin and higher HOMA-IR at baseline and at follow-up an average of 5.4 years later. Carbon 115-122 insulin Homo sapiens 195-202 27834049-9 2018 Biofilm community characteristics (C/N ratio) may also be an influential determinant of PFAS bioaccumulation. Carbon 35-36 phosphoribosylformylglycinamidine synthase Homo sapiens 88-92 29881969-7 2018 In samples from a Saharan Dust event and in samples with the lowest and the highest OCsec, ATR-FTIR analysis allowed us to identify organic functional groups including the non-acid organic hydroxyl C-OH group (e.g., sugars, anhydrosugars, and polyols), carbonyl C=O group, carboxylic acid COOH group, aromatic and aliphatic unsaturated C=C-H group, aliphatic saturated C-C-H group, and amine NH2 group. Carbon 198-199 ATR serine/threonine kinase Homo sapiens 91-94 29881969-7 2018 In samples from a Saharan Dust event and in samples with the lowest and the highest OCsec, ATR-FTIR analysis allowed us to identify organic functional groups including the non-acid organic hydroxyl C-OH group (e.g., sugars, anhydrosugars, and polyols), carbonyl C=O group, carboxylic acid COOH group, aromatic and aliphatic unsaturated C=C-H group, aliphatic saturated C-C-H group, and amine NH2 group. Carbon 198-199 ATR serine/threonine kinase Homo sapiens 91-94 29947902-5 2018 The limit of detection for sodium azide at the silicone-oil-based carbon paste electrode was found to be 0.1 muM. Carbon 66-72 latexin Homo sapiens 109-112 30012899-3 2018 An unusual and paradoxical effect of bovine LS and synthetic model LS with SP-B/-C was bactericidal to Staphylococcus aureus and Escherichia coli. Carbon 81-82 surfactant protein B Bos taurus 75-79 29728002-0 2018 Interfacial growth of nitrogen-doped carbon with multi-functional groups on the MoS2 skeleton for efficient Pb(II) removal. Carbon 37-43 submaxillary gland androgen regulated protein 3B Homo sapiens 108-114 29972020-0 2018 Metal-Free All-Carbon Nanohybrid for Ultrasensitive Photoelectrochemical Immunosensing of alpha-Fetoprotein. Carbon 15-21 alpha fetoprotein Homo sapiens 90-107 29903411-3 2018 Docking studies of both isomers with AR suggested that (R)-6c is in closer spatial proximity to helix-12 of the AR than (S)-6c, which is the most important common motif in the secondary structure of AR for the expression of antagonistic activity. Carbon 120-126 androgen receptor Homo sapiens 37-39 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 88-94 Sp3 transcription factor Homo sapiens 80-83 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 88-94 Sp3 transcription factor Homo sapiens 84-87 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 95-101 Sp3 transcription factor Homo sapiens 80-83 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 95-101 Sp3 transcription factor Homo sapiens 84-87 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 95-101 Sp3 transcription factor Homo sapiens 80-83 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 95-101 Sp3 transcription factor Homo sapiens 84-87 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 95-101 Sp3 transcription factor Homo sapiens 80-83 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 95-101 Sp3 transcription factor Homo sapiens 84-87 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 95-101 Sp3 transcription factor Homo sapiens 80-83 31458973-3 2018 Although there are methods for combining heterocyclization and formation of new sp3-sp3 carbon-carbon bonds, these form the carbon-heteroatom bond rather than a carbon-carbon bond of the heterocycle. Carbon 95-101 Sp3 transcription factor Homo sapiens 84-87 29974752-9 2018 They present a saddle-shaped geometry and consist of a relatively small number of sp2 carbon atoms. Carbon 86-92 Sp2 transcription factor Homo sapiens 82-85 29932322-4 2018 Radicals are tolerant of most polar functions, and radical additions to flat sp2 centers are generally easier to accomplish than enolate substitution at tetrahedral sp3 carbons. Carbon 169-176 Sp3 transcription factor Homo sapiens 165-168 29633774-5 2018 These free radical mediated reactions can proceed between almost any sp3 and sp2 carbon centers, allowing introduction of C-C bonds at unconventional positions in metabolites. Carbon 81-87 Sp3 transcription factor Homo sapiens 69-72 29633774-5 2018 These free radical mediated reactions can proceed between almost any sp3 and sp2 carbon centers, allowing introduction of C-C bonds at unconventional positions in metabolites. Carbon 81-87 Sp2 transcription factor Homo sapiens 77-80 29633774-5 2018 These free radical mediated reactions can proceed between almost any sp3 and sp2 carbon centers, allowing introduction of C-C bonds at unconventional positions in metabolites. Carbon 122-123 Sp3 transcription factor Homo sapiens 69-72 29633774-5 2018 These free radical mediated reactions can proceed between almost any sp3 and sp2 carbon centers, allowing introduction of C-C bonds at unconventional positions in metabolites. Carbon 122-123 Sp2 transcription factor Homo sapiens 77-80 29633774-5 2018 These free radical mediated reactions can proceed between almost any sp3 and sp2 carbon centers, allowing introduction of C-C bonds at unconventional positions in metabolites. Carbon 124-125 Sp3 transcription factor Homo sapiens 69-72 29633774-5 2018 These free radical mediated reactions can proceed between almost any sp3 and sp2 carbon centers, allowing introduction of C-C bonds at unconventional positions in metabolites. Carbon 124-125 Sp2 transcription factor Homo sapiens 77-80 29627528-4 2018 We detected 11 single nucleotide polymorphisms (SNP) of 7 one-carbon metabolism pathway genes (including MTHFR, MTR, MTRR, ALDH1L1, GART, SHMT1 and CBS) in donor livers and analyzed their association with HBV reinfection after liver transplantation. Carbon 62-68 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 117-121 30019251-0 2018 Fibrinogen binding-dependent cytotoxicity and degradation of single-walled carbon nanotubes. Carbon 75-81 fibrinogen beta chain Homo sapiens 0-10 30019251-2 2018 In this work, we investigated the effects of human fibrinogen-surface coatings on the biodegradation and cytotoxicity of carboxylated single-walled carbon nanotubes (SWCNTs). Carbon 148-154 fibrinogen beta chain Homo sapiens 51-61 29578014-2 2018 The activated carbon (AC) was synthesized from the solid waste obtained in the extraction process of the peroxidase enzyme and the magnetic composite was used as support for the immobilization of soybean peroxidase (SP). Carbon 14-20 peroxidase Glycine max 105-115 29578014-2 2018 The activated carbon (AC) was synthesized from the solid waste obtained in the extraction process of the peroxidase enzyme and the magnetic composite was used as support for the immobilization of soybean peroxidase (SP). Carbon 14-20 peroxidase Glycine max 204-214 29627528-4 2018 We detected 11 single nucleotide polymorphisms (SNP) of 7 one-carbon metabolism pathway genes (including MTHFR, MTR, MTRR, ALDH1L1, GART, SHMT1 and CBS) in donor livers and analyzed their association with HBV reinfection after liver transplantation. Carbon 62-68 aldehyde dehydrogenase 1 family member L1 Homo sapiens 123-130 29578014-2 2018 The activated carbon (AC) was synthesized from the solid waste obtained in the extraction process of the peroxidase enzyme and the magnetic composite was used as support for the immobilization of soybean peroxidase (SP). Carbon 22-24 peroxidase Glycine max 105-115 29578014-2 2018 The activated carbon (AC) was synthesized from the solid waste obtained in the extraction process of the peroxidase enzyme and the magnetic composite was used as support for the immobilization of soybean peroxidase (SP). Carbon 22-24 peroxidase Glycine max 204-214 29757487-3 2018 The phenines were woven into a polygonal framework that was composed of 168 sp2 -hybridized carbon atoms. Carbon 92-98 Sp2 transcription factor Homo sapiens 76-79 30007394-1 2018 While the issue of properly describing the out-of-plane bends (OPBs) in sp2 hybridized carbon atoms has reappeared for c-SiC2H2, the present quantum chemical study provides a new characterization of this molecule in order to aid in its potential detection in astrophysically relevant studies. Carbon 87-93 Sp2 transcription factor Homo sapiens 72-75 29684908-1 2018 In this work, voltammetric data recorded by a glassy carbon electrode (GCE) was used to investigate the interactions of tolcapone (Tasmar, TAS) with human serum albumin (HSA) at the electrode surface. Carbon 53-59 albumin Homo sapiens 155-168 29684908-1 2018 In this work, voltammetric data recorded by a glassy carbon electrode (GCE) was used to investigate the interactions of tolcapone (Tasmar, TAS) with human serum albumin (HSA) at the electrode surface. Carbon 53-59 albumin Homo sapiens 170-173 29343666-6 2018 Interestingly, some MrpL32DeltaC derivatives exhibited temperature-sensitive (ts) growth on medium with non-fermentable carbon sources. Carbon 120-126 mitochondrial 54S ribosomal protein YmL32 Saccharomyces cerevisiae S288C 20-26 29881857-0 2018 Development of pyrene-stacked carbon nanotube-based hybrid: measurement of NO3- ions using fluorescence spectroscopy. Carbon 30-36 NBL1, DAN family BMP antagonist Homo sapiens 75-78 29796566-6 2018 This review updates the rapidly developing field of transient directing groups for C-H functionalisation on sp2 and sp3 carbon centres, to form new C-C and C-X bonds. Carbon 120-126 Sp3 transcription factor Homo sapiens 116-119 29962160-5 2018 There were significant negative correlations between catalase and the ratio of soil carbon and nitrogen, and urease was positively correlated to total nitrogen and soil moisture. Carbon 84-90 catalase Homo sapiens 53-61 29973666-2 2018 Although carbon nanotubes affect expression of the MHC class I-like CD1d molecule, whether GO can influence immune responses of CD1d-dependent invariant natural killer T (iNKT) cells remains unclear. Carbon 9-15 CD1d1 antigen Mus musculus 68-72 30042828-15 2018 Activation of immune-response by carbon ions markedly enhanced anti-EGFR based endoradiotherapy suggesting further evaluation of this novel and promising radioimmunotherapy concept. Carbon 33-39 epidermal growth factor receptor Homo sapiens 68-72 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 erb-b2 receptor tyrosine kinase 2 Homo sapiens 173-178 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 tumor protein p53 Homo sapiens 255-258 29689442-0 2018 Ameliorating mitochondrial dysfunction restores carbon ion-induced cognitive deficits via co-activation of NRF2 and PINK1 signaling pathway. Carbon 48-54 nuclear factor, erythroid derived 2, like 2 Mus musculus 107-111 29698786-9 2018 The obtained results provide better understanding of fibrinogen unfolding induced by different factors and are important for improvement of biomedical applications, such as fibrinogen-based protein matrixes and carbon-based biomaterials. Carbon 211-217 fibrinogen beta chain Homo sapiens 53-63 29986647-4 2018 RESULTS: By using chromosome conformation capture carbon copy (5C) technology in primary human renal cyst epithelial cells, we identify novel contacts of the PKD2 promoter with chromatin regions, which display characteristics of regulatory elements. Carbon 50-56 polycystin 2, transient receptor potential cation channel Homo sapiens 158-162 29752182-2 2018 The sp2 carbon atoms of the aminoindane skeleton of the known inhibitor were replaced with sp3 carbon atoms to increase the molecular complexity, measured by fraction sp3 (Fsp3). Carbon 8-14 Sp2 transcription factor Homo sapiens 4-7 29752182-2 2018 The sp2 carbon atoms of the aminoindane skeleton of the known inhibitor were replaced with sp3 carbon atoms to increase the molecular complexity, measured by fraction sp3 (Fsp3). Carbon 95-101 Sp3 transcription factor Homo sapiens 91-94 29597179-4 2018 A very high total organic carbon (TOC) removal value (45.23 mg L-1) was obtained in the first 60 min of the electro-Fenton treatment of an aqueous solution of NBB (0.25 mM) at 300 mA, indicating the mineralization efficiency of the electro-Fenton method. Carbon 26-32 immunoglobulin kappa variable 1-16 Homo sapiens 63-66 29689442-7 2018 Furthermore, in the mouse hippocampal neuronal cells, overexpression of NRF2/PINK1 strikingly protected the hippocampal neurons from carbon ion-elicited toxic insults. Carbon 133-139 nuclear factor, erythroid derived 2, like 2 Mus musculus 72-76 29689442-8 2018 Thus, these data suggest that alleviation of the sustained mitochondrial dysfunction and oxidative stress through co-modulation of NRF2 and PINK1 may be in charge of restoration of the cognitive impairments in a mouse model of high-LET carbon ion irradiation. Carbon 236-242 nuclear factor, erythroid derived 2, like 2 Mus musculus 131-135 29674024-6 2018 Amperometric study demonstrated that the Au-Ni nanocomposites modified glassy carbon electrode (GCE) exhibited a high sensitivity of 2133.5 mA M-1 cm-2 and a wide linear range (0.4-900 muM) toward the oxidation of glucose with a detection limit as low as 0.1 muM. Carbon 78-84 latexin Homo sapiens 185-188 29674024-6 2018 Amperometric study demonstrated that the Au-Ni nanocomposites modified glassy carbon electrode (GCE) exhibited a high sensitivity of 2133.5 mA M-1 cm-2 and a wide linear range (0.4-900 muM) toward the oxidation of glucose with a detection limit as low as 0.1 muM. Carbon 78-84 latexin Homo sapiens 259-262 29870226-4 2018 At the same time, the catalyst structure is further modified during the transfer hydrogenation, leading to a noticeable increase of sp2 carbons. Carbon 136-143 Sp2 transcription factor Homo sapiens 132-135 29705306-3 2018 This study aimed to evaluate the parametric influence of tip sonication on the characteristics of sp2 carbon structure in graphene nanoplatelets by varying the sonication time and respective energy at three different amplitudes (60%, 80% and 100%). Carbon 102-108 Sp2 transcription factor Homo sapiens 98-101 29954131-3 2018 Here, we performed a meta-analysis in order to investigate the relationship between the intake of four dietary one-carbon metabolism-related B vitamins (B2, B6, folate, and B12) and the risk of esophageal cancer (EC). Carbon 115-121 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 173-176 29904763-2 2018 Ni3-xCoxAl-LDHs (x = 0, 1, 2, and 3) were synthesized on carbon paper by a unipolar pulse electrodeposition (UPED) method and used as electrodes in energy storage systems. Carbon 57-63 xenotropic and polytropic retrovirus receptor 1 Homo sapiens 17-35 29893387-1 2018 Hydroalumination of R-P(H)-C[triple bond, length as m-dash]C-tBu with bulky H-Al[CH(SiMe3)2]2 afforded the new P-H functionalized Al/P-based frustrated Lewis pair R-P(H)-C[[double bond, length as m-dash]C(H)-tBu]-AlR2 [R = CH(SiMe3)2; FLP 7]. Carbon 27-28 aldo-keto reductase family 1 member B Homo sapiens 213-217 29543985-2 2018 Although the bis(phenylsulfonyl)methyl group is typically introduced as an sp3 -carbon nucleophile, it is demonstrated that it can also function as an effective sp2 -carbon electrophile in the presence of organolithium nucleophiles. Carbon 80-86 Sp3 transcription factor Homo sapiens 75-78 29543985-2 2018 Although the bis(phenylsulfonyl)methyl group is typically introduced as an sp3 -carbon nucleophile, it is demonstrated that it can also function as an effective sp2 -carbon electrophile in the presence of organolithium nucleophiles. Carbon 80-86 Sp2 transcription factor Homo sapiens 161-164 29543985-3 2018 Alkyl- and aryllithiums couple with the central carbon of the bis(phenylsulfonyl)methyl unit to ultimately generate trisubstituted alkenes, comprising formal sp3 -sp2 and sp2 -sp2 cross-couplings between organolithium reagents and bis(sulfones). Carbon 48-54 Sp3 transcription factor Homo sapiens 158-161 29543985-3 2018 Alkyl- and aryllithiums couple with the central carbon of the bis(phenylsulfonyl)methyl unit to ultimately generate trisubstituted alkenes, comprising formal sp3 -sp2 and sp2 -sp2 cross-couplings between organolithium reagents and bis(sulfones). Carbon 48-54 Sp2 transcription factor Homo sapiens 163-166 29543985-3 2018 Alkyl- and aryllithiums couple with the central carbon of the bis(phenylsulfonyl)methyl unit to ultimately generate trisubstituted alkenes, comprising formal sp3 -sp2 and sp2 -sp2 cross-couplings between organolithium reagents and bis(sulfones). Carbon 48-54 Sp2 transcription factor Homo sapiens 171-174 29543985-3 2018 Alkyl- and aryllithiums couple with the central carbon of the bis(phenylsulfonyl)methyl unit to ultimately generate trisubstituted alkenes, comprising formal sp3 -sp2 and sp2 -sp2 cross-couplings between organolithium reagents and bis(sulfones). Carbon 48-54 Sp2 transcription factor Homo sapiens 171-174 29920957-4 2018 In this study, we report the synthesis and characterization of a new calix[5]phyrin bearing one sp3 -hybridized carbon atom as a pi-expanded calix[n]phyrin. Carbon 112-118 Sp3 transcription factor Homo sapiens 96-99 29873118-1 2018 The chemical modification of an sp2 hybridized carbon surface in a controllable manner is very challenging but also crucial for many applications. Carbon 47-53 Sp2 transcription factor Homo sapiens 32-35 29808673-1 2018 Carbon nanothreads are a new type of one-dimensional sp3-carbon nanomaterial formed by slow compression and decompression of benzene. Carbon 0-6 Sp3 transcription factor Homo sapiens 53-56 29808673-1 2018 Carbon nanothreads are a new type of one-dimensional sp3-carbon nanomaterial formed by slow compression and decompression of benzene. Carbon 57-63 Sp3 transcription factor Homo sapiens 53-56 29792672-10 2018 Mycothiol (MSH) and ergothioneine (EGT), two small-molecule thiols that are known for their redox-relevant roles in protection against various endogenous and exogenous stresses, function through two unusual S-glycosylations to mediate an eight-carbon aminosugar transfer, activation, and modification during the molecular assembly and tailoring processes in lincosamide antibiotic biosynthesis. Carbon 244-250 msh homeobox 2 Homo sapiens 11-14 29878021-0 2018 Fluorescence immunosensor for cardiac troponin T based on Forster resonance energy transfer (FRET) between carbon dot and MoS2 nano-couple. Carbon 107-113 troponin T2, cardiac type Homo sapiens 30-48 29626814-3 2018 We found that the changes in this coefficient value due to incorporation of nitrogen atoms into the carbon network are related to the spatial configurations of the sp2 bonded carbon atoms, order degree and sp2 clusters size. Carbon 100-106 Sp2 transcription factor Homo sapiens 164-167 29790346-0 2018 Ligand-Free Iron-Catalyzed Carbon(sp2)-Carbon(sp2) Cross-Coupling of Alkenyllithium with Vinyl Halides. Carbon 27-33 Sp2 transcription factor Homo sapiens 34-37 29790346-0 2018 Ligand-Free Iron-Catalyzed Carbon(sp2)-Carbon(sp2) Cross-Coupling of Alkenyllithium with Vinyl Halides. Carbon 27-33 Sp2 transcription factor Homo sapiens 46-49 29792705-2 2018 Key features include a one-pot [O]-oxa-Michael cascade to establish the polyoxygenated dibenzofuran core followed by a Pd-catalyzed directed ortho-C(sp2)-H arylation to complete the fully functionalized carbon skeleton. Carbon 203-209 Sp2 transcription factor Homo sapiens 147-152 29626814-3 2018 We found that the changes in this coefficient value due to incorporation of nitrogen atoms into the carbon network are related to the spatial configurations of the sp2 bonded carbon atoms, order degree and sp2 clusters size. Carbon 100-106 Sp2 transcription factor Homo sapiens 206-209 29626814-3 2018 We found that the changes in this coefficient value due to incorporation of nitrogen atoms into the carbon network are related to the spatial configurations of the sp2 bonded carbon atoms, order degree and sp2 clusters size. Carbon 175-181 Sp2 transcription factor Homo sapiens 164-167 29863730-0 2018 Three-dimensional sp2 carbon networks prepared by ultrahigh temperature treatment for ultrafast lithium-sulfur batteries. Carbon 22-28 Sp2 transcription factor Homo sapiens 18-21 29800511-7 2018 Importantly, the Fe-PCN/S has a smaller phase nucleation overpotential of polysulfides than nitrogen-doped carbon alone for the formation of nanoscale of Li2S as revealed by ex situ SEM, which enhance lithium-ion diffusion in Li2S, and therefore a high rate performance and remarkable cycle life of Li-sulfur batteries were achieved. Carbon 107-113 pericentrin Homo sapiens 20-23 29863730-2 2018 Herein, aiming the application of Li-S at high current rates, we coupled a sp2 carbon configuration consisting of 3D carbon nanotubes/graphene prepared by ultrahigh temperature treatment (2850 C) with S (2850CNTs-Gra-S) for application in Li-S batteries. Carbon 117-123 Sp2 transcription factor Homo sapiens 75-78 29863730-4 2018 The 3D sp2 carbon network ensures ultrafast ion/electron transfer and efficient heat dissipation to protect the integrity of the separator when the Li-S battery is running at an ultrahigh rate. Carbon 11-17 Sp2 transcription factor Homo sapiens 7-10 29873371-6 2018 Although the optimized differential spin density of states at the Fermi level (SDOS) of the kinked carbon chains is higher than that of bulk Fe, the magnetic moment is as low as 0.3muB. Carbon 99-105 nudix hydrolase 16 like 1 Homo sapiens 79-83 29873371-9 2018 Surprisingly, the V and VII-doped carbon chains show a strong non-zero SDOS, which has its origin in the p-shells. Carbon 34-40 nudix hydrolase 16 like 1 Homo sapiens 71-75 29873371-10 2018 The VII-doped carbon chains give the SDOS of the opposite sign. Carbon 14-20 nudix hydrolase 16 like 1 Homo sapiens 37-41 29767947-7 2018 The detection is fast; signal saturation can be achieved in <60 s. The sensor can also be fabricated on gold-plated screen-printed carbon electrodes, electrode substrates that are ideal for cost-effective analysis of Pb(II) in real-world settings. Carbon 134-140 submaxillary gland androgen regulated protein 3B Homo sapiens 220-226 29706565-4 2018 In particular, via GATA6, metastatic cells in the liver upregulate the enzyme aldolase B (ALDOB), which enhances fructose metabolism and provides fuel for major pathways of central carbon metabolism during tumor cell proliferation. Carbon 181-187 aldolase, fructose-bisphosphate B Homo sapiens 78-88 29706565-4 2018 In particular, via GATA6, metastatic cells in the liver upregulate the enzyme aldolase B (ALDOB), which enhances fructose metabolism and provides fuel for major pathways of central carbon metabolism during tumor cell proliferation. Carbon 181-187 aldolase, fructose-bisphosphate B Homo sapiens 90-95 29977295-1 2018 The work highlights inhibition-based Acetylcholinesterase (AChE) fabrication using composite nanomaterial comprising tin oxide nanoparticles (SnO2) and carboxylated multiwalled carbon nanotubes (cMWCNTs) for detection of pesticide methyl parathion (MP) in water samples. Carbon 177-183 acetylcholinesterase (Cartwright blood group) Homo sapiens 37-57 29977295-1 2018 The work highlights inhibition-based Acetylcholinesterase (AChE) fabrication using composite nanomaterial comprising tin oxide nanoparticles (SnO2) and carboxylated multiwalled carbon nanotubes (cMWCNTs) for detection of pesticide methyl parathion (MP) in water samples. Carbon 177-183 acetylcholinesterase (Cartwright blood group) Homo sapiens 59-63 29233911-4 2018 Here, we performed for the first time an in-depth site-specific N- and O-glycosylation analysis of C1-Inh combining various mass spectrometric approaches, including C18-porous graphitized carbon (PGC)-LC-ESI-QTOF-MS/MS applying stepping-energy collision-induced dissociation (CID) and electron-transfer dissociation (ETD). Carbon 188-194 Bardet-Biedl syndrome 9 Homo sapiens 165-168 29685969-2 2018 The compounds with linker lengths of 6 and 7 carbon atoms were the most potent in histone deacetylase (HDAC) inhibition, and were specific submicromolar inhibitors of the HDAC1, HDAC6 and HDAC8 isoforms. Carbon 45-51 histone deacetylase 6 Homo sapiens 178-183 29480553-0 2018 Performance of an in situ activated carbon treatment to reduce PCB availability in an active harbor. Carbon 36-42 pyruvate carboxylase Homo sapiens 63-66 29523891-3 2018 Using the Tara Oceans metagenomic dataset, we have identified draft genomes of nine bacteria that possess the genomic potential for anoxygenic phototrophy, carbon fixation via the Calvin-Benson-Bassham cycle, and the oxidation of sulfite and thiosulfate. Carbon 156-162 TRIO and F-actin binding protein Homo sapiens 10-14 29583060-0 2018 PAPep Inhibits Secretion of Poly(I:C)-Induced Inflammatory Cytokines and ICAM-1 Expression in Corneal Fibroblasts by Suppressing the NF-kappaB/p38 Pathway. Carbon 35-37 nuclear factor kappa B subunit 1 Homo sapiens 133-142 29583060-0 2018 PAPep Inhibits Secretion of Poly(I:C)-Induced Inflammatory Cytokines and ICAM-1 Expression in Corneal Fibroblasts by Suppressing the NF-kappaB/p38 Pathway. Carbon 35-37 mitogen-activated protein kinase 14 Homo sapiens 143-146 29686055-4 2018 Mutation of RAPTOR1B resulted in a strong reduction of TOR kinase activity, leading to massive changes in central carbon and nitrogen metabolism, accumulation of excess starch, and induction of autophagy. Carbon 114-120 target of rapamycin Arabidopsis thaliana 15-18 29569779-13 2018 Furthermore, differential responses of cinv1 cinv2 seedlings to exogenous sugar supplementation support a function of CINVs in influencing carbon partitioning in Arabidopsis. Carbon 139-145 cytosolic invertase 1 Arabidopsis thaliana 39-44 29414082-0 2018 Sandwich-type electrochemical immunosensor based on Au@Ag supported on functionalized phenolic resin microporous carbon spheres for ultrasensitive analysis of alpha-fetoprotein. Carbon 113-119 alpha fetoprotein Homo sapiens 159-176 29860377-0 2018 Nitrate Reductase Modulation in Response to Changes in C/N Balance and Nitrogen Source in Arabidopsis. Carbon 44-45 nitrate reductase 1 Arabidopsis thaliana 0-17 29414093-2 2018 In this article, highly sensitive and low-cost impedimetric immunosensor using single-chain fragment variable antibody fragments was developed for quantitative detection of human epidermal growth factor receptor 2 from serum employing gold nanoparticle-modified disposable screen-printed carbon electrodes. Carbon 288-294 erb-b2 receptor tyrosine kinase 2 Homo sapiens 179-213 29701994-2 2018 Here, antibodies (anti-TNF-alpha) were immobilized on the floating electrodes of carbon nanotube devices, enabling selective and real-time detection of TNF-alpha among various cytokines linked to IBD. Carbon 81-87 tumor necrosis factor Mus musculus 23-32 29425853-3 2018 Screen-printed carbon electrode (SPCE) was applied for achieving the detection of AFP. Carbon 15-21 alpha fetoprotein Homo sapiens 82-85 29621549-2 2018 The deletion mutant of OSH6 showed growth defects on n-alkanes of 10-16 carbons. Carbon 72-79 oxysterol-binding protein OSH6 Saccharomyces cerevisiae S288C 23-27 29962372-7 2018 HOSCN decreased polyI:C-induced apoptosis and the expression levels of IFNB1, IFNL1, IFNL2 and IFNL3 mRNAs. Carbon 3-4 interferon lambda 3 Homo sapiens 95-100 29708744-4 2018 The SAR study revealed a relationship between the length of the residues at carbon C-3 of the steroid molecule and the positive modulatory effect at GluN1/GluN2B receptors for various D-ring modifications. Carbon 76-82 glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens 149-154 29701994-2 2018 Here, antibodies (anti-TNF-alpha) were immobilized on the floating electrodes of carbon nanotube devices, enabling selective and real-time detection of TNF-alpha among various cytokines linked to IBD. Carbon 81-87 tumor necrosis factor Mus musculus 152-161 29846664-5 2018 Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms. Carbon 85-86 Sp2 transcription factor Homo sapiens 149-152 29846664-2 2018 Carbon K-emission spectrum showed characteristic intensity distribution of not only sp2 bonding but also sp3 bonding. Carbon 0-6 Sp2 transcription factor Homo sapiens 84-87 29846664-2 2018 Carbon K-emission spectrum showed characteristic intensity distribution of not only sp2 bonding but also sp3 bonding. Carbon 0-6 Sp3 transcription factor Homo sapiens 105-108 29846664-3 2018 The a-CNx film with lager x, which has a larger macroscopic electric resistivity, shows a larger content of the carbon sp3: C-C bonding signal. Carbon 6-7 Sp3 transcription factor Homo sapiens 119-122 29846664-5 2018 Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms. Carbon 85-86 Sp2 transcription factor Homo sapiens 187-190 29846664-3 2018 The a-CNx film with lager x, which has a larger macroscopic electric resistivity, shows a larger content of the carbon sp3: C-C bonding signal. Carbon 124-125 Sp3 transcription factor Homo sapiens 119-122 29846664-4 2018 Furthermore, the dependence of spectral intensity distribution on x suggests the presence of sp2: C-N and sp3: C-N bonding. Carbon 98-99 Sp2 transcription factor Homo sapiens 93-96 29846664-5 2018 Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms. Carbon 85-86 Sp3 transcription factor Homo sapiens 200-203 29846664-5 2018 Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms. Carbon 154-155 Sp2 transcription factor Homo sapiens 149-152 29846664-5 2018 Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms. Carbon 154-155 Sp2 transcription factor Homo sapiens 149-152 29846664-5 2018 Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms. Carbon 154-155 Sp2 transcription factor Homo sapiens 149-152 29415250-10 2018 Total soil nitrogen (TN, positively) and total organic carbon (TOC, negatively) are the most important explanatory factors for SLA variation at both intra- and interspecific levels. Carbon 55-61 Src like adaptor Homo sapiens 127-130 29722982-2 2018 In this reaction, one C-N bond was cleaved, and two new C-N bonds and one C(sp2)-C(sp2) bond were constructed in one pot. Carbon 22-23 Sp2 transcription factor Homo sapiens 74-79 29722982-2 2018 In this reaction, one C-N bond was cleaved, and two new C-N bonds and one C(sp2)-C(sp2) bond were constructed in one pot. Carbon 22-23 Sp2 transcription factor Homo sapiens 81-86 29405989-0 2018 The label-free immunosensor based on rhodium@palladium nanodendrites/sulfo group functionalized multi-walled carbon nanotubes for the sensitive analysis of carcino embryonic antigen. Carbon 109-115 CEA cell adhesion molecule 3 Homo sapiens 156-181 29676410-1 2018 Recent studies have improved our understanding of the mechanism and dynamics of the bimolecular nucleophilic substitution (SN2) reaction at the carbon center. Carbon 144-150 solute carrier family 38 member 5 Homo sapiens 123-126 29672042-4 2018 The amorphous carbon networks produced using both parameter sets at 300 K are similar to each other, with the first peak positions of pair distribution function curves located between the graphite sp2 bond peak position and the diamond sp3 bond peak position. Carbon 14-20 Sp2 transcription factor Homo sapiens 197-200 29672042-4 2018 The amorphous carbon networks produced using both parameter sets at 300 K are similar to each other, with the first peak positions of pair distribution function curves located between the graphite sp2 bond peak position and the diamond sp3 bond peak position. Carbon 14-20 Sp3 transcription factor Homo sapiens 236-239 29701215-0 2018 Correction: New carbon allotropes in sp + sp3 bonding networks consisting of C8 cubes. Carbon 16-22 Sp3 transcription factor Homo sapiens 42-45 29701215-1 2018 Correction for "New carbon allotropes in sp + sp3 bonding networks consisting of C8 cubes" by Jian-Tao Wang et al., Phys. Carbon 20-26 Sp3 transcription factor Homo sapiens 46-49 29454260-2 2018 The transformation products m/z 795, 835, 515/1030 and 532 can be formed through attack of OH on the conjugated carbon double bonds of Adda. Carbon 112-118 adducin 1 Homo sapiens 135-139 29676410-5 2018 The double-inversion mechanism revealed recently for the SN2 reaction at the carbon center is also observed for the title reaction at the nitrogen center. Carbon 77-83 solute carrier family 38 member 5 Homo sapiens 57-60 29721703-1 2018 Calixphyrins are hybrid macrocycles that contain both sp2- and sp3-hybridized carbon atoms and hence bear analogy to both porphyrins and calixpyrroles. Carbon 78-84 Sp3 transcription factor Homo sapiens 63-66 29524325-2 2018 However, the limited number of storage sites for lithium ions within the sp2 -carbon hexahedrons leads to the low storage capacity. Carbon 78-84 Sp2 transcription factor Homo sapiens 73-76 29638108-1 2018 In this work, a versatile photoelectrochemical paper-based sensor based on N-carbon dots/TiO2-Pt-modified paper in situ is developed for sensitive detection of carcinoembryonic antigen (CEA) in clinical serum samples. Carbon 77-83 CEA cell adhesion molecule 3 Homo sapiens 160-184 29638108-1 2018 In this work, a versatile photoelectrochemical paper-based sensor based on N-carbon dots/TiO2-Pt-modified paper in situ is developed for sensitive detection of carcinoembryonic antigen (CEA) in clinical serum samples. Carbon 77-83 CEA cell adhesion molecule 3 Homo sapiens 186-189 29455077-2 2018 The subject of research was the analysis of Raman spectra of two types of fibrous carbon nanomaterials, of great potential for biomedical applications, incubated with human serum albumin (HSA). Carbon 82-88 albumin Homo sapiens 173-186 29447123-5 2018 AFM tapping stalls the growth of pores upon further plasma exposure at a level that coincides with the fraction of sp2 carbons in the GO starting material. Carbon 119-126 Sp2 transcription factor Homo sapiens 115-118 29720254-0 2018 Concurrent interactome and metabolome analysis reveals role of AKT1 in central carbon metabolism. Carbon 79-85 AKT serine/threonine kinase 1 Homo sapiens 63-67 29720254-3 2018 Considering this, we investigated the role of AKT1 in central carbon metabolism. Carbon 62-68 AKT serine/threonine kinase 1 Homo sapiens 46-50 29720254-4 2018 The role of AKT1 has already been established in the process of cell cycle, but its contribution to the central carbon metabolism is sparsely studied. Carbon 112-118 AKT serine/threonine kinase 1 Homo sapiens 12-16 29578268-7 2018 X-ray absorption and density functional theory studies support a mechanism of operation that relies on the polarization of sp2 hybridized carbon atoms. Carbon 138-144 Sp2 transcription factor Homo sapiens 123-126 29721703-2 2018 Due to the presence of sp3-hybridized carbon atoms, pi-conjugation is disrupted in calixphyrins, which leads to conformational flexibility. Carbon 38-44 Sp3 transcription factor Homo sapiens 23-26 29719052-0 2018 Effect of single-walled carbon nanotubes on cytochrome P450 activity in human liver microsomes in vitro. Carbon 24-30 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 44-59 29577452-1 2018 Carbonization of organic compounds with a highest occupied molecular orbital (HOMO) level more positive than 1.3 V practically automatically results in highly sp2 -conjugated, heteroatom-doped carbons. Carbon 193-200 Sp2 transcription factor Homo sapiens 159-162 29602984-0 2018 Interactions between carbon and nitrogen sources depend on RIM15 and determine fermentative or respiratory growth in Saccharomyces cerevisiae. Carbon 21-27 protein kinase RIM15 Saccharomyces cerevisiae S288C 59-64 29602984-7 2018 This study reveals the existence of synergic and diverse roles of carbon and nitrogen sources that are affected by RIM15, influencing the fermentative and respiratory growth of S. cerevisiae. Carbon 66-72 protein kinase RIM15 Saccharomyces cerevisiae S288C 115-120 29719052-6 2018 Testosterone 6beta-hydroxylation and midazolam 1"-hydroxylation, which are catalysed by both CYP3A4 and CYP3A5 in liver microsomes, were decreased by 25% and 45%, respectively, in the presence of 0.1 mg/ml SO-SWCNT. Carbon 209-214 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 93-99 29719052-6 2018 Testosterone 6beta-hydroxylation and midazolam 1"-hydroxylation, which are catalysed by both CYP3A4 and CYP3A5 in liver microsomes, were decreased by 25% and 45%, respectively, in the presence of 0.1 mg/ml SO-SWCNT. Carbon 209-214 cytochrome P450 family 3 subfamily A member 5 Homo sapiens 104-110 29498810-3 2018 Here, we note that different biogeochemical-model scenarios plausibly explaining globally synchronous PSF-delta13 Ccarbonate converge: via mechanistic requirements for extensive anoxia in marine sediments to support sedimentary build-up of 13 C-depleted carbon. Carbon 114-115 insulin like growth factor binding protein 7 Homo sapiens 102-105 29687134-0 2018 Low-energy 3D sp2 carbons with versatile properties beyond graphite and graphene. Carbon 18-25 Sp2 transcription factor Homo sapiens 14-17 29687134-1 2018 Carbon materials with full sp2-hybridized bonding, e.g. zero-dimensional (0D) fullerenes, 1D carbon nanotubes, and 2D graphene, possess outstanding and unparalleled properties, and have unique scientific and technological importance. Carbon 0-6 Sp2 transcription factor Homo sapiens 27-30 29687134-1 2018 Carbon materials with full sp2-hybridized bonding, e.g. zero-dimensional (0D) fullerenes, 1D carbon nanotubes, and 2D graphene, possess outstanding and unparalleled properties, and have unique scientific and technological importance. Carbon 93-99 Sp2 transcription factor Homo sapiens 27-30 29687134-2 2018 The theoretical design and experimental exploration of other types of novel sp2 carbon allotropes, especially with 3D architectures, is always a compelling scientific theme. Carbon 80-86 Sp2 transcription factor Homo sapiens 76-79 29687134-3 2018 Here we proposed a class of low-energy 3D sp2 carbons with exceptional properties, not only possessing excellent mechanical properties such as high 3D strength, rubber-like ultra-stretchability, and negative Poisson"s ratio, but also including the electronic properties of graphite-like metallicity and graphene-like Dirac cone, which are the desirable properties across a broad range of potential applications. Carbon 46-53 Sp2 transcription factor Homo sapiens 42-45 29687134-4 2018 Furthermore, a design route was suggested to access these 3D sp2 carbons by the polymerization of edge-functionalized graphene nanoribbon arrays. Carbon 65-72 Sp2 transcription factor Homo sapiens 61-64 29492816-6 2018 Correlation analysis between PCB concentrations and total organic carbon indicated that local input or atmospheric deposition was the primary controls of spatial variation of PCBs. Carbon 66-72 pyruvate carboxylase Homo sapiens 29-32 29498810-3 2018 Here, we note that different biogeochemical-model scenarios plausibly explaining globally synchronous PSF-delta13 Ccarbonate converge: via mechanistic requirements for extensive anoxia in marine sediments to support sedimentary build-up of 13 C-depleted carbon. Carbon 115-121 insulin like growth factor binding protein 7 Homo sapiens 102-105 29498810-4 2018 We hypothesize that bioturbation qualitatively reduced marine sediment anoxia by exposing sediments to oxygenated overlying waters, which ultimately contributed to decreasing the carbon cycle"s subsequent susceptibility to PSF- delta13 Ccarbonate . Carbon 179-185 insulin like growth factor binding protein 7 Homo sapiens 223-226 29498810-5 2018 Bioturbation may also have reduced the quantity of (isotopically light) organic-derived carbon available to contribute to PSF- delta13 Ccarbonate via ocean crust carbonatization at depth. Carbon 88-94 insulin like growth factor binding protein 7 Homo sapiens 122-125 29498810-6 2018 We conduct a comparative modelling exercise in which we introduce bioturbation to existing model scenarios for PSF- delta13 Ccarbonate : expressing both the anoxic proportion of marine sediments, and the global organic carbon burial efficiency, as a decreasing function of bioturbation. Carbon 125-131 insulin like growth factor binding protein 7 Homo sapiens 111-114 29694444-0 2018 One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status. Carbon 4-10 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens 104-108 29360546-1 2018 This paper describes the application of novel nanocomposite material polyaniline/multiwall carbon nanotubes/starch (designated as PCS) as a good electrode material for electrochemical sensing. Carbon 91-97 PCS Homo sapiens 130-133 29121482-6 2018 The sum of the QMS signals across all m/z after removal of the NH4+, NO3-, and SO42- signals was highly correlated with the carbon content of oxalic acid (C2H2O4) standards. Carbon 124-130 NBL1, DAN family BMP antagonist Homo sapiens 69-72 28675568-0 2018 Sciatic nerve regeneration by transplantation of Schwann cells via erythropoietin controlled-releasing polylactic acid/multiwalled carbon nanotubes/gelatin nanofibrils neural guidance conduit. Carbon 131-137 erythropoietin Homo sapiens 67-81 32254080-1 2018 A new carbon allotrope, graphdiyne (GDY), with a highly pi-conjugated structure of sp- and sp2-hybridized carbon networks, has recently emerged and been used as a superior carbon additive to boost the activity of water oxidation catalysts. Carbon 6-12 Sp2 transcription factor Homo sapiens 91-94 32254080-1 2018 A new carbon allotrope, graphdiyne (GDY), with a highly pi-conjugated structure of sp- and sp2-hybridized carbon networks, has recently emerged and been used as a superior carbon additive to boost the activity of water oxidation catalysts. Carbon 106-112 Sp2 transcription factor Homo sapiens 91-94 32254080-1 2018 A new carbon allotrope, graphdiyne (GDY), with a highly pi-conjugated structure of sp- and sp2-hybridized carbon networks, has recently emerged and been used as a superior carbon additive to boost the activity of water oxidation catalysts. Carbon 106-112 Sp2 transcription factor Homo sapiens 91-94 32254080-3 2018 Density functional theory (DFT) calculations prove that the sp- and sp2-hybridized GDY shows both superior electron capture and excellent electron transfer ability compared to that of the conventional sp2-hybridized carbon materials. Carbon 216-222 Sp2 transcription factor Homo sapiens 68-71 32254080-3 2018 Density functional theory (DFT) calculations prove that the sp- and sp2-hybridized GDY shows both superior electron capture and excellent electron transfer ability compared to that of the conventional sp2-hybridized carbon materials. Carbon 216-222 Sp2 transcription factor Homo sapiens 201-204 29604581-2 2018 Based on structure-activity relationship, N-substituents with a branched chain and a shorter carbon chain on the amidine N-atom exhibited more promising activity against Gram-negative and MDR-Gram-positive bacteria; compounds 5c and 5i were the most powerful candidate compounds. Carbon 93-99 malic enzyme complex, mitochondrial Mus musculus 188-191 29691665-0 2018 Electrochemical immunoassay for the carcinoembryonic antigen based on the use of a glassy carbon electrode modified with an octahedral Cu2O-gold nanocomposite and staphylococcal protein for signal amplification. Carbon 90-96 CEA cell adhesion molecule 3 Homo sapiens 36-60 29275222-0 2018 Perylenetetracarboxylic acid and carbon quantum dots assembled synergistic electrochemiluminescence nanomaterial for ultra-sensitive carcinoembryonic antigen detection. Carbon 33-39 CEA cell adhesion molecule 3 Homo sapiens 133-157 29505044-2 2018 The alignment amplitude is substantially enhanced over common methods which greatly benefits measurements particularly on sp3 carbons. Carbon 126-133 Sp3 transcription factor Homo sapiens 122-125 29687401-0 2018 A photoelectrochemical aptasensor for thrombin based on the use of carbon quantum dot-sensitized TiO2 and visible-light photoelectrochemical activity. Carbon 67-73 coagulation factor II, thrombin Homo sapiens 38-46 29557161-5 2018 Using a combination of infrared and X-ray absorption spectroscopy techniques, we correlate the changes in quantum relaxation rates with the conversion of sp2 carbon to C-O and C-H bonds on the diamond surface. Carbon 158-164 Sp2 transcription factor Homo sapiens 154-157 29690640-0 2018 Non-Canonical Activation of the Epidermal Growth Factor Receptor by Carbon Nanoparticles. Carbon 68-74 epidermal growth factor receptor Homo sapiens 32-64 29690640-2 2018 In our earlier studies, we observed an activation of the EGFR and subsequent signaling events after the exposure of epithelial cells to carbon nanoparticles. Carbon 136-142 epidermal growth factor receptor Homo sapiens 57-61 29690640-4 2018 Caveolin-1 is a key player that co-localizes with the EGFR upon receptor activation by carbon nanoparticles. Carbon 87-93 caveolin 1 Homo sapiens 0-10 29690640-4 2018 Caveolin-1 is a key player that co-localizes with the EGFR upon receptor activation by carbon nanoparticles. Carbon 87-93 epidermal growth factor receptor Homo sapiens 54-58 29483189-0 2018 Deletion of the neural tube defect-associated gene Mthfd1l disrupts one-carbon and central energy metabolism in mouse embryos. Carbon 72-78 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like Mus musculus 51-58 29775444-14 2018 c - n=5 (IgA+IgG) gr. Carbon 0-1 CD79a molecule Homo sapiens 9-12 29557161-5 2018 Using a combination of infrared and X-ray absorption spectroscopy techniques, we correlate the changes in quantum relaxation rates with the conversion of sp2 carbon to C-O and C-H bonds on the diamond surface. Carbon 168-169 Sp2 transcription factor Homo sapiens 154-157 29611701-2 2018 Herein, we present a novel and facile route for synthesis of iron-, cobalt-, and nitrogen-codoped carbon nanopolyhedra electrocatalysts (Fe,Co,N-CNP) by one-step pyrolysis of a new type of Fe/Co bimetal zeolitic imidazolate framework (Fe,Co-ZIF) crystals that were self-assembled by oxygen-free solvothermal reaction of Fe2+ and Co2+ with 2-methylimidazole. Carbon 98-104 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 145-148 29557161-5 2018 Using a combination of infrared and X-ray absorption spectroscopy techniques, we correlate the changes in quantum relaxation rates with the conversion of sp2 carbon to C-O and C-H bonds on the diamond surface. Carbon 176-177 Sp2 transcription factor Homo sapiens 154-157 29367051-14 2018 The influence of NO3-, NO2-, IC and heavy metal Pb and Zn on bacterial community might via their influence on the functional groups involving nitrogen, carbon and metal metabolisms. Carbon 152-158 NBL1, DAN family BMP antagonist Homo sapiens 17-20 29428647-0 2018 Overview of As(V) adsorption on Zr-functionalized activated carbon for aqueous streams remediation. Carbon 60-66 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 12-17 29428647-1 2018 The present work introduces a simple methodology of carbon modification with zirconium, using an organic complexing ligand, as efficient media for selective As(V) removal. Carbon 52-58 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 157-162 29569919-1 2018 Carbon nanothreads are a new one-dimensional sp3 carbon nanomaterial. Carbon 0-6 Sp3 transcription factor Homo sapiens 45-48 29569919-1 2018 Carbon nanothreads are a new one-dimensional sp3 carbon nanomaterial. Carbon 49-55 Sp3 transcription factor Homo sapiens 45-48 29654372-1 2018 The authors describe an electrochemical aptasensor for thrombin that is based on the use of a glassy carbon electrode (GCE) modified with polydopamine that is loaded with silver nanoparticles (PDA/AgNPs). Carbon 101-107 coagulation factor II, thrombin Homo sapiens 55-63 29331814-0 2018 Characterization of sp3 bond content of carbon films deposited by high power gas injection magnetron sputtering method by UV and VIS Raman spectroscopy. Carbon 40-46 Sp3 transcription factor Homo sapiens 20-23 29650959-4 2018 We develop a nanozyme using nitrogen-doped porous carbon nanospheres which possess four enzyme-like activities (oxidase, peroxidase, catalase and superoxide dismutase) responsible for reactive oxygen species regulation. Carbon 50-56 catalase Homo sapiens 133-141 29518333-1 2018 G-4 calculations are used to explore which carbon atoms of methylated butadienes, methylated cyclopentadienes, and methylated benzenes are most readily protonated to yield delocalized allyl and pentadienyl cations. Carbon 43-49 chromosome 6 open reading frame 47 Homo sapiens 0-3 29643459-3 2018 We use Bayes theorem to weight members of a perturbed parameter ensemble with varying land and ocean carbon uptake, to derive an estimate for the fossil fuel (FF) carbon budget of 469 PgC since 1850, with a 95% likelihood range of (411,528) PgC. Carbon 163-169 progastricsin Homo sapiens 184-187 29643459-5 2018 Our best estimate of the total (FF + LUC) carbon budget for 1.5 C is therefore 699 PgC, which corresponds to about 11 years of current emissions. Carbon 42-48 progastricsin Homo sapiens 84-87 29578560-1 2018 Carbon-containing NiCo2S4 hollow-nanoflake structures were fabricated by a one-step solvothermal method using CS2 as a single source for sulfidation and carbonization. Carbon 0-6 chorionic somatomammotropin hormone 2 Homo sapiens 110-113 29542920-7 2018 Comparative studies with a similar yet planar pi-conjugated system suggested that the curved structure of the bowl-shaped pi-radical cation facilitates the sigma-dimerization at one of the internal sp2-hybridized carbon atoms. Carbon 213-219 Sp2 transcription factor Homo sapiens 198-201 29226424-5 2018 Poly(I:C) induced the production of prostaglandin E2 in OHSCs by increasing cyclooxygenase (COX-2) and microsomal prostaglandin E synthase (mPGES)-1. Carbon 7-8 mitochondrially encoded cytochrome c oxidase II Homo sapiens 92-97 29396708-6 2018 Laboratory tests showed that changes in the influent carbon source concentration and composition significantly affect MEC total internal resistance and capacitance estimated by the model. Carbon 53-59 C-C motif chemokine ligand 28 Homo sapiens 118-121 29460993-5 2018 Concurrently, sp3 -hybridized carbon atoms are converted into sp-hybridized ones, that is, an alkyl group is transformed into an alkynyl moiety. Carbon 30-36 Sp3 transcription factor Homo sapiens 14-17 29226424-10 2018 Activation of EP2 receptor reversed the Poly(I:C)/LPS-induced phosphorylation of the mitogen activated protein kinases (MAPKs) ERK, p38 MAPK and c-Jun N-terminal kinase (JNK) in microglia. Carbon 47-48 mitogen-activated protein kinase 8 Homo sapiens 145-168 29226424-10 2018 Activation of EP2 receptor reversed the Poly(I:C)/LPS-induced phosphorylation of the mitogen activated protein kinases (MAPKs) ERK, p38 MAPK and c-Jun N-terminal kinase (JNK) in microglia. Carbon 47-48 mitogen-activated protein kinase 8 Homo sapiens 170-173 29451311-3 2018 ZmSUT1 is essential for carbon allocation in maize, but the relative contribution to apoplasmic phloem loading and retrieval of sucrose leaking from the translocation path is not known. Carbon 24-30 tocopherol cyclase, chloroplastic Zea mays 0-6 29517777-5 2018 The synthesized Pd(ii) and Ni(ii) complexes as catalysts have been investigated in the C-S cross-coupling of indoles and active methylenes. Carbon 87-88 mitochondrially encoded cytochrome c oxidase II Homo sapiens 19-21 29601504-3 2018 Hence, we have developed a simple, cost effective, and label-free electrochemical immunoassay for the measurement of CRP in a drop of serum sample using an immunosensor strip made up of a screen printed carbon electrode (SPE) modified with anti-CRP functionalized gold nanoparticles (AuNPs). Carbon 203-209 C-reactive protein Homo sapiens 117-120 29383355-0 2018 New carbon allotropes in sp + sp3 bonding networks consisting of C8 cubes. Carbon 4-10 Sp3 transcription factor Homo sapiens 30-33 29383355-2 2018 The resulting sp + sp3-hybridized cubane-yne and cubane-diyne structures consisting of C8 cubes can be characterized as a cubic crystalline modification of linear carbon chains, but energetically more favorable than the simplest linear carbyne chain and the cubic tetrahedral diamond and yne-diamond consisting of C4 tetrahedrons. Carbon 163-169 Sp3 transcription factor Homo sapiens 19-22 29582197-0 2018 Reduce the Sensitivity of CL-20 by Improving Thermal Conductivity Through Carbon Nanomaterials. Carbon 74-80 epithelial membrane protein 1 Homo sapiens 26-31 29582197-1 2018 The graphene (rGO) and carbon nanotube (CNT) were adopted to enhance the thermal conductivity of CL-20-based composites as conductive fillers. Carbon 23-29 epithelial membrane protein 1 Homo sapiens 97-102 29501826-8 2018 Maximum removal of MC-LR was achieved under the following optimum conditions; sample pH 4, carbon dosage concentration 10,000 mg L-1 and contact time of 34 min. Carbon 91-97 immunoglobulin kappa variable 1-16 Homo sapiens 129-132 29527607-2 2018 Gas adsorption isotherms and binary breakthrough experiments show dramatically large selectivities for CO2 over N2 and CH4, which are the highest among physisorbents at operating temperatures suitable for postcombustion carbon capture and natural gas separations. Carbon 220-226 COP9 signalosome subunit 4 Drosophila melanogaster 119-122 29590160-2 2018 Biosynthesis of LC-PUFAs from dietary 18 carbon PUFAs in tissues such as the liver is highly associated with genetic variation within the fatty acid desaturase (FADS) gene cluster, containing FADS1 and FADS2 that encode the rate-limiting desaturation enzymes in the LC-PUFA biosynthesis pathway. Carbon 41-47 fatty acid desaturase 2 Homo sapiens 202-207 29517777-5 2018 The synthesized Pd(ii) and Ni(ii) complexes as catalysts have been investigated in the C-S cross-coupling of indoles and active methylenes. Carbon 87-88 mitochondrially encoded cytochrome c oxidase II Homo sapiens 30-32 29054021-0 2018 QPRTase modified N-doped carbon quantum dots: A fluorescent bioprobe for selective detection of neurotoxin quinolinic acid in human serum. Carbon 25-31 quinolinate phosphoribosyltransferase Homo sapiens 0-7 29461037-1 2018 A new type of thermosensitive dual-template epitope molecular imprinting polymer was prepared and coated on magnetic carbon nanotubes (MCNTs@D-EMIP) for simultaneous recognition of human serum albumin (HSA) and transferrin (Trf) via the strategies of dual-template epitope imprinting, metal chelation imprinting, and distillation-precipitation polymerization (DPP). Carbon 117-123 albumin Homo sapiens 187-206 29096367-9 2018 The voltammetric SMN carbon nanofiber-based immunosensor showed high sensitivity (detection limit of 0.75pg/ml) and selectivity against other proteins such as cystic fibrosis transmembrane conductance regulator (CFTR) and dystrophin (DMD). Carbon 21-27 CF transmembrane conductance regulator Homo sapiens 159-210 29096367-9 2018 The voltammetric SMN carbon nanofiber-based immunosensor showed high sensitivity (detection limit of 0.75pg/ml) and selectivity against other proteins such as cystic fibrosis transmembrane conductance regulator (CFTR) and dystrophin (DMD). Carbon 21-27 CF transmembrane conductance regulator Homo sapiens 212-216 29593399-2 2018 In the present study, the interactions of carbon-based nanoparticles (NPs) such as fullerene and fullerenol having different surface chemistry with Abeta were investigated using molecular dynamics simulations and docking studies. Carbon 42-48 amyloid beta precursor protein Homo sapiens 148-153 32226136-3 2018 Obtained molecular parameters confirm the hyperconjugation in the pyridine ring and the sp2 hybridization concept of the nitrogen and carbon atoms in the ring. Carbon 134-140 Sp2 transcription factor Homo sapiens 88-91 29461037-1 2018 A new type of thermosensitive dual-template epitope molecular imprinting polymer was prepared and coated on magnetic carbon nanotubes (MCNTs@D-EMIP) for simultaneous recognition of human serum albumin (HSA) and transferrin (Trf) via the strategies of dual-template epitope imprinting, metal chelation imprinting, and distillation-precipitation polymerization (DPP). Carbon 117-123 transferrin Homo sapiens 211-222 29525808-13 2018 Interestingly, carbon irradiation triggered a burst of IFN-g and IL-12 in LPS or CpG treated DCs, which provide novel insights into the combination of immunotherapy and carbon ion radiotherapy. Carbon 15-21 interferon gamma Homo sapiens 55-60 29451291-4 2018 The CoII-MOF modified glassy carbon electrode (GCE) shows good electrocatalytic activity towards glucose oxidation. Carbon 29-35 mitochondrially encoded cytochrome c oxidase II Homo sapiens 4-8 29780523-6 2018 The [5]helicene is responsible for the chiroptical activity while the push-pull geometry and the extended network of sp2 carbons are factors favoring the nonlinear absorption. Carbon 121-128 Sp2 transcription factor Homo sapiens 117-120 29525808-13 2018 Interestingly, carbon irradiation triggered a burst of IFN-g and IL-12 in LPS or CpG treated DCs, which provide novel insights into the combination of immunotherapy and carbon ion radiotherapy. Carbon 169-175 interferon gamma Homo sapiens 55-60 29525808-14 2018 Finally, we found that carbon ion irradiation induced apoptosis and migration suppression was p38 dependent. Carbon 23-29 mitogen-activated protein kinase 14 Homo sapiens 94-97 29525808-15 2018 CONCLUSIONS Our present study demonstrated that carbon ion irradiation induced apoptosis in DCs, and impaired DCs function mainly through the p38 signaling pathway. Carbon 48-54 mitogen-activated protein kinase 14 Homo sapiens 142-145 29536038-0 2018 Large-scale polymeric carbon nanotube membranes with sub-1.27-nm pores. Carbon 22-28 SUB1 regulator of transcription Homo sapiens 53-58 29356373-2 2018 The processing of GO to reduced graphene oxide (rGO) was performed in 1-64 s, and sp2 /sp2 +sp3 carbon concentration increased from approximately 20 % to 90 %. Carbon 96-102 Sp3 transcription factor Homo sapiens 92-95 29536038-1 2018 We report the first characterization study of commercial prototype carbon nanotube (CNT) membranes consisting of sub-1.27-nm-diameter CNTs traversing a large-area nonporous polysulfone film. Carbon 67-73 SUB1 regulator of transcription Homo sapiens 113-118 29965476-2 2018 The results showed that adding 50 mg L-1 organic carbon accelerated the start-up of the CANON granular sludge process. Carbon 49-55 L1 cell adhesion molecule Homo sapiens 37-40 29466008-0 2018 Raman Microscopy Insights on the Out-of-Plane Electrical Transport of Carbon Nanotube-Doped PEDOT:PSS Electrodes for Solar Cell Applications. Carbon 70-76 PSS Homo sapiens 98-101 29327475-1 2018 Graphene, a 2D material consisting of a single layer of sp2 -hybridized carbon, exhibits inert activity as an electrocatalyst, while the incorporation of heteroatoms (such as N) into the framework can tune its electronic properties. Carbon 72-78 Sp2 transcription factor Homo sapiens 56-59 29468229-8 2018 Overall, it seems difficult for Li+ to penetrate through the sp2-carbon wall, because a very high inletting energy is required to open the entrance. Carbon 65-71 Sp2 transcription factor Homo sapiens 61-64 30966305-2 2018 Inspired by the synergistic effect of natural nacre, we developed a novel approach to fabricate high-performance SPI nanocomposite films based on 2D graphene (G) nanosheets and 1D carbon nanotubes (CNTs) and nanofibrillated cellulose (NFC) using a casting method. Carbon 180-186 chromogranin A Homo sapiens 113-116 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 0-1 Sp2 transcription factor Homo sapiens 117-120 29983483-5 2018 Both IR and reflectivity measurements led to similar high proportions ( 50%) of H atoms, but there was a significant discrepancy in the sp2/sp3 hybridization ratios of C atoms (sp2/sp3 = 1.5 from IR and 0.25 from reflectivity). Carbon 169-170 Sp2 transcription factor Homo sapiens 137-140 29983483-5 2018 Both IR and reflectivity measurements led to similar high proportions ( 50%) of H atoms, but there was a significant discrepancy in the sp2/sp3 hybridization ratios of C atoms (sp2/sp3 = 1.5 from IR and 0.25 from reflectivity). Carbon 169-170 Sp3 transcription factor Homo sapiens 141-144 29299865-4 2018 By the C1s spectrum, activated carbons from IR1-500 contained more carboxyl groups (-COOH) and carbonyl groups (C=O), which played an important role in copper ions adsorption. Carbon 31-38 complement C1s Homo sapiens 7-10 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 101-102 Sp3 transcription factor Homo sapiens 147-150 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 101-102 Sp2 transcription factor Homo sapiens 117-120 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 0-1 Sp3 transcription factor Homo sapiens 147-150 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 101-102 Sp3 transcription factor Homo sapiens 147-150 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 161-167 Sp2 transcription factor Homo sapiens 117-120 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 101-102 Sp2 transcription factor Homo sapiens 117-120 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 161-167 Sp3 transcription factor Homo sapiens 147-150 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 101-102 Sp3 transcription factor Homo sapiens 147-150 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 121-127 Sp2 transcription factor Homo sapiens 117-120 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 121-127 Sp3 transcription factor Homo sapiens 147-150 29275478-4 2018 Copper ions functioned to delocalize the coordination of pi of the lone paired electron in azo bond, C=C bond of the sp2 carbon to form C-C of the sp3 amorphous carbon in benzene and naphthalene. Carbon 101-102 Sp2 transcription factor Homo sapiens 117-120 29164502-2 2018 It is achieved by adding a methyl group to the fifth carbon atom of cytosine residues within cytosine-phosphate-guanine (CpG) and non-CpG dinucleotide sites using DNA methyltransferase (DNMT) enzymes for de novo and maintenance methylation processes. Carbon 53-59 DNA methyltransferase (cytosine-5) 1 Mus musculus 163-184 29593128-4 2018 C-90 inhibition coefficient I0.5 magnitude was approximately 20 muM and the Hill coefficient nH was 0.55. Carbon 0-1 latexin Homo sapiens 64-67 29164502-2 2018 It is achieved by adding a methyl group to the fifth carbon atom of cytosine residues within cytosine-phosphate-guanine (CpG) and non-CpG dinucleotide sites using DNA methyltransferase (DNMT) enzymes for de novo and maintenance methylation processes. Carbon 53-59 DNA methyltransferase (cytosine-5) 1 Mus musculus 186-190 29519422-3 2018 Plasma functionalized (N2 and O2) and stabilized Graphene Oxide (GO) thin layers in a hybrid with amorphous carbon (aC) induced the expression of vascular endothelial growth factor (VEGF) and osteoprotegerin (OPG) growth factors in fibroblasts (hGF) and, more remarkably, in osteoblasts (hFOB) cells confirming the suitability for tissue regeneration and osteo-integration applications. Carbon 108-114 vascular endothelial growth factor A Homo sapiens 146-180 29448656-4 2018 Spectroscopic analysis revealed the systematic evolution of r-GO with tuneable structural, optical and electrical properties as results of varying annealing temperatures (100-400 C), due to restoration of sp2 conducting carbon network i.e., the formation of new -C C- network and Stones-Wales defect. Carbon 221-227 Sp2 transcription factor Homo sapiens 206-209 29448679-3 2018 The sp2/sp3 bonded carbon ratio in the grown films increased as the CH4 content increased up to 3 Vol% and then decreased beyond 4 Vol%. Carbon 19-25 Sp2 transcription factor Homo sapiens 4-7 29448679-3 2018 The sp2/sp3 bonded carbon ratio in the grown films increased as the CH4 content increased up to 3 Vol% and then decreased beyond 4 Vol%. Carbon 19-25 Sp3 transcription factor Homo sapiens 8-11 29519422-3 2018 Plasma functionalized (N2 and O2) and stabilized Graphene Oxide (GO) thin layers in a hybrid with amorphous carbon (aC) induced the expression of vascular endothelial growth factor (VEGF) and osteoprotegerin (OPG) growth factors in fibroblasts (hGF) and, more remarkably, in osteoblasts (hFOB) cells confirming the suitability for tissue regeneration and osteo-integration applications. Carbon 108-114 vascular endothelial growth factor A Homo sapiens 182-186 31458523-0 2018 Microwave Permittivity of Trace sp2 Carbon Impurities in Sub-Micron Diamond Powders. Carbon 36-42 Sp2 transcription factor Homo sapiens 32-35 29172962-7 2018 Moreover, the useful life of the GAC bed is increased from 45 min in the column fed with raw leachate to 170 min in the column fed with pretreated leachate and 5000 mg L-1 of H2O2 at pH of 8 that subsequently increased the activated carbon adsorption capacity. Carbon 233-239 L1 cell adhesion molecule Homo sapiens 168-179 29595155-1 2018 Simultaneous removal of carbon and nutrients (CNP) in a single laboratory-scale bioreactor is advantageous in terms of reactor volume and energy consumption. Carbon 24-30 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 46-49 29359558-0 2018 Insulin Detection Using a Corona Phase Molecular Recognition Site on Single-Walled Carbon Nanotubes. Carbon 83-89 insulin Homo sapiens 0-7 29359558-2 2018 In this work, we employ a high-throughput screening of a library of poly(ethylene glycol) (PEG)-conjugated lipids adsorbed onto near-infrared fluorescent single-walled carbon nanotubes to discover a corona phase selective for insulin. Carbon 168-174 insulin Homo sapiens 226-233 29359558-4 2018 The insulin protein has no prior affinity toward the C16-PEG(2000 Da)-ceramide molecules in free solution, verified by isothermal titration calorimetry, and the interaction occurs only upon their adsorption onto the single-walled carbon nanotube scaffolds. Carbon 230-236 insulin Homo sapiens 4-11 31458523-1 2018 Microwave dielectric loss tangent measurements are demonstrated as a method for quantifying trace sp2-hybridized carbon impurities in sub-micron diamond powders. Carbon 113-119 Sp2 transcription factor Homo sapiens 98-101 31458523-5 2018 After annealing, a small increase in sp2 carbon was identified from the XPS C 1s and Auger spectra, the EELS sigma* peak in the C 1s spectra, and the D and G bands in Raman spectroscopy, although a quantifiable diamond to G-band peak ratio was unobtainable. Carbon 41-47 Sp2 transcription factor Homo sapiens 37-40 31458523-7 2018 Microwave cavity perturbation measurements show that the dielectric loss tangent increases with increasing sp2 bonding, with the most pertinent finding being that these values correlate with other measurements and that trace concentrations of sp2 carbon as small as 5% can be detected. Carbon 247-253 Sp2 transcription factor Homo sapiens 107-110 31458523-7 2018 Microwave cavity perturbation measurements show that the dielectric loss tangent increases with increasing sp2 bonding, with the most pertinent finding being that these values correlate with other measurements and that trace concentrations of sp2 carbon as small as 5% can be detected. Carbon 247-253 Sp2 transcription factor Homo sapiens 243-246 29394066-3 2018 Substrate scope studies reveal that the selectivity of cyclization was controlled by the substrates with sp3 and sp2 hybridization of carbon at the 2 position in quinazolinone. Carbon 134-140 Sp2 transcription factor Homo sapiens 113-116 29266939-1 2018 Cytochrome P450 (CYP) monooxygenases catalyze the oxidation of chemically inert carbon-hydrogen bonds in diverse endogenous and exogenous organic compounds by atmospheric oxygen. Carbon 80-86 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-15 29266939-1 2018 Cytochrome P450 (CYP) monooxygenases catalyze the oxidation of chemically inert carbon-hydrogen bonds in diverse endogenous and exogenous organic compounds by atmospheric oxygen. Carbon 80-86 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 17-20 29298877-1 2018 In our recent study, we have demonstrated that short carbon chain n-alcohols (up to octanol) stimulated while long carbon chain n-alcohols inhibited the conductance of connexin (Cx) 36 (Cx36) gap junction (GJ) channels. Carbon 115-121 gap junction protein delta 2 Homo sapiens 168-184 29363974-3 2018 This method not only provides an efficient way to prepare various substituted azaarenes but also achieves the selective construction of C(sp2)-X (X = Br, Cl) bonds from a halogen anion and nucleophilic carbon atom via a free-radical process. Carbon 202-208 Sp2 transcription factor Homo sapiens 136-141 28961546-4 2018 The fully characterized NKA-LCP material was immobilized onto a glassy carbon electrode, forming a highly stable enzyme electrode and a novel sensing platform. Carbon 71-77 tachykinin precursor 1 Homo sapiens 24-27 29594452-0 2018 Lysozyme aptasensor based on a glassy carbon electrode modified with a nanocomposite consisting of multi-walled carbon nanotubes, poly(diallyl dimethyl ammonium chloride) and carbon quantum dots. Carbon 38-44 lysozyme Homo sapiens 0-8 29594452-0 2018 Lysozyme aptasensor based on a glassy carbon electrode modified with a nanocomposite consisting of multi-walled carbon nanotubes, poly(diallyl dimethyl ammonium chloride) and carbon quantum dots. Carbon 112-118 lysozyme Homo sapiens 0-8 29594452-0 2018 Lysozyme aptasensor based on a glassy carbon electrode modified with a nanocomposite consisting of multi-walled carbon nanotubes, poly(diallyl dimethyl ammonium chloride) and carbon quantum dots. Carbon 112-118 lysozyme Homo sapiens 0-8 29298877-1 2018 In our recent study, we have demonstrated that short carbon chain n-alcohols (up to octanol) stimulated while long carbon chain n-alcohols inhibited the conductance of connexin (Cx) 36 (Cx36) gap junction (GJ) channels. Carbon 115-121 gap junction protein delta 2 Homo sapiens 186-190 29058865-5 2018 alphaMSH peptide sequences, evaluated for conjugation to the PEG-Cy5-C" dot nanoparticles, bound to MC1-R with high affinity and targeted melanoma in syngenetic and xenografted melanoma mouse models. Carbon 65-66 melanocortin 1 receptor Mus musculus 100-105 29211475-2 2018 The new inhibitors incorporated an sp3 hybridized carbon atom at the 7-position of the lactam moiety present in lead compound 1 as a replacement for a dimethylisoxazole group. Carbon 50-56 Sp3 transcription factor Homo sapiens 35-38 29422671-0 2018 Site-specific phosphorylation of TRANSPARENT TESTA GLABRA1 mediates carbon partitioning in Arabidopsis seeds. Carbon 68-74 myb domain protein 0 Arabidopsis thaliana 51-58 29422671-3 2018 Here we show that phosphorylation of TRANSPARENT TESTA GLABRA1 (TTG1) is regulated by SHAGGY-like kinases 11/12 (SK11/12) and that this mediates carbon flow to fatty acid synthesis and seed coat traits in Arabidopsis seeds. Carbon 145-151 myb domain protein 0 Arabidopsis thaliana 55-62 29422671-3 2018 Here we show that phosphorylation of TRANSPARENT TESTA GLABRA1 (TTG1) is regulated by SHAGGY-like kinases 11/12 (SK11/12) and that this mediates carbon flow to fatty acid synthesis and seed coat traits in Arabidopsis seeds. Carbon 145-151 shaggy-related kinase 11 Arabidopsis thaliana 113-120 29422671-6 2018 Therefore, site-specific phosphorylation of TTG1 by SK11/SK12 regulates carbon partitioning between zygotic and maternal sinks in seeds. Carbon 72-78 shaggy-related kinase 11 Arabidopsis thaliana 52-56 29416063-2 2018 Here, we show that Pemt and Gnmt, key one-carbon cycle genes regulating PC/SAM levels, are downregulated after feeding, leading to decreased PC and increased SAM levels, but these effects are blunted in small heterodimer partner (SHP)-null or FGF15-null mice. Carbon 42-48 phosphatidylethanolamine N-methyltransferase Mus musculus 19-23 29298388-4 2018 The resulting Fe@Aza-PON catalyst showed electrocatalytic activity (half-wave potential, 0.839 V; Tafel slope, 60 mV decade-1) comparable to commercial Pt on activated carbon (Pt/C, 0.826 V and 90 mV decade-1). Carbon 168-174 paraoxonase 1 Homo sapiens 21-24 29415006-7 2018 X-ray crystallography revealed that a single betaOG molecule is present in the Nef dimer, with the 8-carbon acyl chain of the ligand binding to a hydrophobic pocket formed by the dimer interface. Carbon 101-107 S100 calcium binding protein B Homo sapiens 79-82 28988960-5 2018 We analysed the impact of mce4A expression on carbon shift initiated during cholesterol utilization necessary for long term survival of mycobacterium. Carbon 46-52 Mce family protein Mce4A Mycobacterium tuberculosis H37Rv 26-31 29424668-3 2018 In the present study, recombinant human interferon gamma (IFNG) was expressed for the first time in Kluyveromyces lactis expression system and its expression was optimized by varying growth parameters and carbon source concentration with the aim of increasing recombinant protein production level. Carbon 205-211 interferon gamma Homo sapiens 40-63 29441126-13 2018 Overexpression of CTT1 and PRX1 in the recombinant strain S. cerevisiae YRH396 deriving from S. cerevisiae YB-2625 increased cell growth when xylose was used as the sole carbon source, leading to 13.5 and 18.1%, respectively, more xylose consumption. Carbon 170-176 catalase T Saccharomyces cerevisiae S288C 18-22 29363959-6 2018 Chemically or electrochemically generated Co(I) porphyrins are known to be highly reactive in solutions containing alkyl or aryl halides, and this property was utilized to in situ generate a new series of methyl carbon-bonded cobalt(III) porphyrins with the same pi-extending or highly electron-withdrawing substituents as the initial Co(II) derivatives. Carbon 212-218 mitochondrially encoded cytochrome c oxidase III Homo sapiens 233-236 29363959-6 2018 Chemically or electrochemically generated Co(I) porphyrins are known to be highly reactive in solutions containing alkyl or aryl halides, and this property was utilized to in situ generate a new series of methyl carbon-bonded cobalt(III) porphyrins with the same pi-extending or highly electron-withdrawing substituents as the initial Co(II) derivatives. Carbon 212-218 mitochondrially encoded cytochrome c oxidase II Homo sapiens 335-341 29363959-7 2018 The electrosynthesized carbon-bonded Co(III) porphyrins were then characterized as to their own electrochemical and spectroscopic properties after the addition of one, two, or three electrons in nonaqueous media. Carbon 23-29 mitochondrially encoded cytochrome c oxidase III Homo sapiens 37-44 29292571-0 2018 Thermoregulated Phase-Transition Synthesis of Two-Dimensional Carbon Nanoplates Rich in sp2 Carbon and Unimodal Ultramicropores for Kinetic Gas Separation. Carbon 62-68 Sp2 transcription factor Homo sapiens 88-91 29292571-3 2018 Here we have developed a thermoregulated phase-transition-assisted synthesis of carbon nanoplates with more than 80 % sp2 carbon, unimodal ultramicropore and a controllable thickness. Carbon 80-86 Sp2 transcription factor Homo sapiens 118-121 29292571-3 2018 Here we have developed a thermoregulated phase-transition-assisted synthesis of carbon nanoplates with more than 80 % sp2 carbon, unimodal ultramicropore and a controllable thickness. Carbon 122-128 Sp2 transcription factor Homo sapiens 118-121 28969942-9 2018 In addition, the knockdown of endogenous duSTING by shRNA significantly reduced the poly (I:C) (pIC), poly (dA:dT), and Tembusu virus (TMUV), induced IFN-beta production and significantly promoted DPV replication in vitro. Carbon 92-93 interferon alpha 1 Homo sapiens 150-153 28938169-2 2018 The study results show that the bonds C(sp3)N is have significant role in the formation of the (1000-1800) cm-1 band, and it is necessary to provide a minimum amount of these bonds to be able to contribute in breaking the symmetry of the sp2 carbon bonds. Carbon 242-248 Sp2 transcription factor Homo sapiens 238-241 29247379-9 2018 Graphical abstract An enzyme-free catalytic amplification based label-free amperometric immunosensor was developed for sensitive detection of neuron-specific enolase (NSE) by use of a AuPd nanoparticle-multiwalled carbon nanotube (MWCNT) composite, ferrocenecarboxaldehyde (Fc-CHO), and chitosan (CS) hybrid hydrogel. Carbon 214-220 enolase 2 Homo sapiens 142-165 29247379-9 2018 Graphical abstract An enzyme-free catalytic amplification based label-free amperometric immunosensor was developed for sensitive detection of neuron-specific enolase (NSE) by use of a AuPd nanoparticle-multiwalled carbon nanotube (MWCNT) composite, ferrocenecarboxaldehyde (Fc-CHO), and chitosan (CS) hybrid hydrogel. Carbon 214-220 enolase 2 Homo sapiens 167-170 28965071-2 2018 Previously we presented three engineered P450BM3 variants for aniline hydroxylation, equipped with a carbon nanotube binding-peptide (CNT-tag) for self-assembly on CNT electrodes. Carbon 101-107 haptoglobin Homo sapiens 117-132 29247379-2 2018 In this study, an enzyme-free catalytic amplification based label-free amperometric immunosensor was developed for sensitive detection of neuron-specific enolase (NSE) by use of a AuPd nanoparticle-multiwalled carbon nanotube (AuPd-MWCNT) composite, ferrocenecarboxaldehyde (Fc-CHO), and chitosan hybrid hydrogel. Carbon 210-216 enolase 2 Homo sapiens 138-161 29247379-2 2018 In this study, an enzyme-free catalytic amplification based label-free amperometric immunosensor was developed for sensitive detection of neuron-specific enolase (NSE) by use of a AuPd nanoparticle-multiwalled carbon nanotube (AuPd-MWCNT) composite, ferrocenecarboxaldehyde (Fc-CHO), and chitosan hybrid hydrogel. Carbon 210-216 enolase 2 Homo sapiens 163-166 29354829-1 2018 A luminescent bimetallic iridium probe C10 was developed through a long soft carbon chain linkage to achieve ratiometric detection of viscosity. Carbon 77-83 homeobox C10 Homo sapiens 39-42 28964940-1 2018 The adsorption of cytochrome c in water onto organic and carbon xerogels with narrow pore size distributions has been studied by carrying out transient and equilibrium batch adsorption experiments. Carbon 57-63 cytochrome c, somatic Homo sapiens 18-30 28611470-4 2018 As the ACE-ring 4a possesses the correct C4,11-quaternary and C10-tertiary carbons, 4a would serve as an advanced intermediate for constructing the entire C19-diterpene alkaloid structures. Carbon 75-82 angiotensin I converting enzyme Homo sapiens 7-10 28611470-4 2018 As the ACE-ring 4a possesses the correct C4,11-quaternary and C10-tertiary carbons, 4a would serve as an advanced intermediate for constructing the entire C19-diterpene alkaloid structures. Carbon 75-82 homeobox C10 Homo sapiens 62-65 29031147-0 2018 As(III) and As(V) adsorption on nanocomposite of hydrated zirconium oxide coated carbon nanotubes. Carbon 81-87 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 12-17 29031147-1 2018 Novel hydrated zirconium oxide (ZrO(OH)2) coated carbon nanotubes (CNTs) were prepared via a filtration-steam hydrolysis method, and were used to remove As(III) and As(V) from drinking water. Carbon 49-55 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 165-170 29194690-0 2018 A carbon 21 steroidal metabolite from progestin, 20beta-hydroxy-5alpha-dihydroprogesterone, stimulates the androgen receptor in prostate cancer cells. Carbon 2-8 androgen receptor Homo sapiens 107-124 28500630-0 2018 E2F is involved in radioresistance of carbon ion induced apoptosis via Bax/caspase 3 signal pathway in human hepatoma cell. Carbon 38-44 BCL2 associated X, apoptosis regulator Homo sapiens 71-74 28500630-0 2018 E2F is involved in radioresistance of carbon ion induced apoptosis via Bax/caspase 3 signal pathway in human hepatoma cell. Carbon 38-44 caspase 3 Homo sapiens 75-84 29286252-2 2018 This strategy allows for efficient functionalization of the benzylic sp3-carbons of aryl carboxylic esters. Carbon 73-80 Sp3 transcription factor Homo sapiens 69-72 29382736-11 2018 AlgR specifically bound to the prrf2 and pvdS promoters in vitro AlgR-dependent pyoverdine production was additionally influenced by carbon source rather than the extracellular iron concentration per se AlgR phosphorylation effects were also examined in a Drosophila melanogaster feeding, murine acute pneumonia, and punch wound infection models. Carbon 133-139 alginate biosynthesis regulatory protein AlgR Pseudomonas aeruginosa PAO1 0-4 29382736-11 2018 AlgR specifically bound to the prrf2 and pvdS promoters in vitro AlgR-dependent pyoverdine production was additionally influenced by carbon source rather than the extracellular iron concentration per se AlgR phosphorylation effects were also examined in a Drosophila melanogaster feeding, murine acute pneumonia, and punch wound infection models. Carbon 133-139 alginate biosynthesis regulatory protein AlgR Pseudomonas aeruginosa PAO1 65-69 29382736-11 2018 AlgR specifically bound to the prrf2 and pvdS promoters in vitro AlgR-dependent pyoverdine production was additionally influenced by carbon source rather than the extracellular iron concentration per se AlgR phosphorylation effects were also examined in a Drosophila melanogaster feeding, murine acute pneumonia, and punch wound infection models. Carbon 133-139 alginate biosynthesis regulatory protein AlgR Pseudomonas aeruginosa PAO1 65-69 29382736-14 2018 Here, we show that the AlgR phosphorylation state inversely controls pyoverdine and pyocyanin production and that this control is carbon source dependent. Carbon 130-136 alginate biosynthesis regulatory protein AlgR Pseudomonas aeruginosa PAO1 23-27 29382736-20 2018 Interestingly, AlgR-dependent pyoverdine production was responsive to carbon source, indicating that this regulation has additional complexities that merit further study. Carbon 70-76 alginate biosynthesis regulatory protein AlgR Pseudomonas aeruginosa PAO1 15-19 29323686-4 2018 The unique framework of sp2 carbon and sp3 silicon atoms leads to unusual in-plane negative Poisson"s ratios and electronic properties superior to both graphene and silicene. Carbon 28-34 Sp2 transcription factor Homo sapiens 24-27 29456803-2 2018 A cocrystal structure of 18 with a NS3/4A protease complex suggests the presence of a H-bond between the polarized C-H of the CHF2 moiety and the backbone carbonyl of Leu135 of the enzyme. Carbon 115-116 hes related family bHLH transcription factor with YRPW motif 1 Homo sapiens 126-130 29215774-3 2018 By exciting the host semiconductor with light that resonates with its electronic transition, we find that halide-containing aryl groups can covalently bond to the sp2 carbon lattice. Carbon 167-173 Sp2 transcription factor Homo sapiens 163-166 29271441-1 2018 Neutrophils were previously shown to digest oxidized carbon nanotubes through a myeloperoxidase (MPO)-dependent mechanism, and graphene oxide (GO) was found to undergo degradation when incubated with purified MPO, but there are no studies to date showing degradation of GO by neutrophils. Carbon 53-59 myeloperoxidase Homo sapiens 97-100 29292454-3 2018 Notably, the cyclometallated Au-C^N complex was identified as the most selective candidate to disrupt the PARP-1 zinc finger domain, forming distinct adducts compared to the coordination compound Auphen. Carbon 32-33 poly(ADP-ribose) polymerase 1 Homo sapiens 106-112 29240401-4 2018 X-ray photoelectron spectroscopy suggested that while all three reagents lowered the content of carbon-oxygen functionalities, solutions of cobaltocene and TFA were the most effective at reducing the material to sp2 carbon. Carbon 216-222 Sp2 transcription factor Homo sapiens 212-215 29329322-9 2018 MEASUREMENTS AND MAIN RESULTS: Loss of Mthfr alters single carbon metabolite levels in the lung and serum including elevated homocysteine and cystathionine and reduced methionine. Carbon 59-65 methylenetetrahydrofolate reductase Mus musculus 39-44 28865272-7 2018 This review focuses on the main factors influencing PCB fate, persistence and bioavailability in soil including PCB mixture congener composition, soil organic carbon forms, microorganism activity, plant species and soil conditions. Carbon 159-165 pyruvate carboxylase Homo sapiens 52-55 29206462-8 2018 However, for the first time we show that increasing the number of deuterated bis-allylic carbons to include both C10 and C13 leads to a massive increase in the PKIE for COX oxygenation of AA. Carbon 89-96 homeobox C10 Homo sapiens 113-116 29965683-5 2018 The Freundlich isotherm showed that activated carbon had better adsorption properties for NH4+-N, TP, and permanganate index in water.When the disk speed was 3 r min-1, the removal efficiency was the best, and the removal rates of NH4+-N, TP and permanganate index were the best at 86.05%, 81.28%, and 77.09%, respectively. Carbon 46-52 CD59 molecule (CD59 blood group) Homo sapiens 162-167 29594480-0 2018 Aptamer based electrochemiluminescent thrombin assay using carbon dots anchored onto silver-decorated polydopamine nanospheres. Carbon 59-65 coagulation factor II, thrombin Homo sapiens 38-46 29594480-12 2018 Graphical abstract Carbon dots (C-dots) placed on polydopamine nanospheres loaded with silver nanoparticles (PDANS@Ag) for electrochemiluminescent (ECL) detection of thrombin. Carbon 19-25 coagulation factor II, thrombin Homo sapiens 166-174 29965689-8 2018 The changes in NO3--N, TN, TP, and TFe mainly occurred in the denitrification biofilter, and the removal of UV254 and the change in the three-dimensional fluorescence intensity mainly occurred in the ozone-activated carbon reactor. Carbon 216-222 NBL1, DAN family BMP antagonist Homo sapiens 15-18 29044777-5 2018 The further process of reduction of paramagnetic species triggers the ethyl migration from carbon(22) to rhodium(III), affording the diamagnetic rhodium(III) meta-benziporphyrin containing the apically coordinated sigma-ethyl ligand providing an example of reversible C(sp2 )-C(sp3 ) bond cleavage. Carbon 91-97 Sp2 transcription factor Homo sapiens 268-273 29203646-9 2018 Subsequent mutagenesis and enzymatic studies of GdpP-C and Rv2837c uncover the complete flipping process and reveal a unified catalytic mechanism for members of both DHH/DHHA1 PDE subfamilies. Carbon 53-54 desert hedgehog signaling molecule Homo sapiens 166-169 29796443-4 2018 As demonstrated both in calorimetric and spectroscopic studies, the greatest influence on the thermotropic properties of the lipid membrane and on the quenching of fluorescence of Laurdan and Prodan was exerted by a derivative named PR47 containing in its structure a two-carbon aliphatic linker with a carbonyl group, as well as bromine and trifluoromethyl substituents. Carbon 272-278 MAGI2 intronic transcript 1 Homo sapiens 233-237 29191006-7 2018 1,3-Phenylenediamine (mPD) was electrodeposited on a carbon-fiber microelectrode to create a size-exclusion membrane, rendering the electrode sensitive to H2O2 fluctuations and pH shifts but not to other commonly studied neurochemicals. Carbon 53-59 mevalonate (diphospho) decarboxylase Mus musculus 22-25 29231218-1 2018 We successfully developed an approach to synthesize a metal oxide- and N-codoped carbon nanosheet, NC@CoO/CuO, derived from a metal-organic framework nanofiber, Cu(ii)-Asp@Co(II) (Asp = l-aspartate). Carbon 81-87 mitochondrially encoded cytochrome c oxidase II Homo sapiens 172-178 30362096-3 2018 ALDH1L1 (cytosolic 10-formyltetrahydrofolate dehydrogenase) is a regulatory enzyme in folate metabolism that controls the overall flux of one-carbon groups in folate-dependent biosynthetic pathways. Carbon 142-148 aldehyde dehydrogenase 1 family member L1 Homo sapiens 0-7 30362096-3 2018 ALDH1L1 (cytosolic 10-formyltetrahydrofolate dehydrogenase) is a regulatory enzyme in folate metabolism that controls the overall flux of one-carbon groups in folate-dependent biosynthetic pathways. Carbon 142-148 aldehyde dehydrogenase 1 family member L1 Homo sapiens 9-58 29074397-1 2018 Here, a method is introduced for construction the aptameric biosensor for biosensing detection of cytochrome C (CYC) based on chain-shape structure of aptasensor by using highly dispersed silver nanoparticles (AgNPs) on acid-oxidized carbon nanotube (CNTs) substrate. Carbon 234-240 cytochrome c, somatic Homo sapiens 98-110 29074397-1 2018 Here, a method is introduced for construction the aptameric biosensor for biosensing detection of cytochrome C (CYC) based on chain-shape structure of aptasensor by using highly dispersed silver nanoparticles (AgNPs) on acid-oxidized carbon nanotube (CNTs) substrate. Carbon 234-240 cytochrome c, somatic Homo sapiens 112-115 30245763-6 2018 Using cyclic voltammetry with a glassy carbon electrode, we have found that NOHA has an oxidation peak at 355 mV with a sensitivity of 5.4 nA/muM. Carbon 39-45 latexin Homo sapiens 142-145 33195796-5 2018 While the upper meter of soil contains 3.57 Tg C, substantial amounts of carbon (3.09 Tg C or 46%) are also stored within the second meter of soil (100-200 cm) in the two deltas. Carbon 73-79 transglutaminase 2 Homo sapiens 86-90 28833909-3 2018 We find the current gross carbon sink in forests recovering from harvests and abandoned agriculture to be -4.4 PgC/year, globally. Carbon 26-32 progastricsin Homo sapiens 111-114 29103116-2 2018 Two activated carbons AC-HP and AC-Na were prepared from argan nut shell by chemical activation method using phosphoric acid (H3PO4) and sodium hydroxide (NaOH), respectively. Carbon 14-21 limb development membrane protein 1 Homo sapiens 22-27 29135286-7 2018 Hence, our study provides novel epigenetic explanation for the association between disordered one carbon metabolism and risk of adiposity, insulin resistance and diabetes and has translational potential. Carbon 98-104 insulin Homo sapiens 139-146 29223096-5 2018 We identified two meta-series compounds 6j and 6k with a two-carbon linker had IC50 values of 3.9 and 4.5 nM for HDAC1, respectively. Carbon 61-67 histone deacetylase 1 Homo sapiens 113-118 30221249-3 2018 Here, we report three-component Co(III)-catalyzed C-H bond additions to dienes and aldehydes that proceeds with high regio- and stereoselectivity resulting in two new carbon-carbon sigma-bonds and from four to six new stereocenters. Carbon 167-173 mitochondrially encoded cytochrome c oxidase III Homo sapiens 32-38 30618316-6 2018 IL-1beta release from carbon particle-exposures was decreased by the presence of Ag in both cell models. Carbon 22-28 interleukin 1 beta Homo sapiens 0-8 30524190-3 2018 In this study, we developed a new nanoultrasound contrast agent by modifying multi-walled carbon nanotubes (MWCNTs) with polyethylene glycol (PEG) and anti-PSMA aptamer. Carbon 90-96 folate hydrolase 1 Homo sapiens 156-160 30097090-2 2018 The radical S-adenosyl-l-methionine enzyme TYW1 modifies tRNAPhe forming the characteristic tricyclic ring via the condensation of carbons 2 and 3 of pyruvate. Carbon 131-138 tRNA-yW synthesizing protein 1 homolog Homo sapiens 43-47 30097093-1 2018 B12-dependent radical SAM enzymes that can perform methylations on sp3 carbon centers are important for functional diversity and regulation of biological activity in several nonribosomal peptides. Carbon 71-77 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 0-3 29127572-1 2018 Strong surface (metal) enhanced fluorescence (SEF or MEF) is observed from clusters and single E coli bacteria cells labeled with Carbon nanodots (CDs), which were synthesized from date pits. Carbon 130-136 interleukin 17 receptor D Homo sapiens 46-49 30221249-3 2018 Here, we report three-component Co(III)-catalyzed C-H bond additions to dienes and aldehydes that proceeds with high regio- and stereoselectivity resulting in two new carbon-carbon sigma-bonds and from four to six new stereocenters. Carbon 174-180 mitochondrially encoded cytochrome c oxidase III Homo sapiens 32-38 28866461-1 2017 A glassy carbon electrode (GCE) modified by calixarene functionalized reduced graphene oxide (CA/RGO) has been fabricated and utilized in this study for simultaneous voltammetric detection of several metal ions, Fe(II), Cd(II) and Pb(II), in aqueous solution. Carbon 9-15 submaxillary gland androgen regulated protein 3B Homo sapiens 220-237 29413358-2 2018 Eighteen and 20-carbon precursors to highly unsaturated n-3 and n-6 fatty acids are the usual substrates for FADS1 and FADS2. Carbon 16-22 fatty acid desaturase 2 Homo sapiens 119-124 29599911-6 2018 Apoptosis analysis showed that caspase 3/7 activity and the percentage of apoptotic cells was dose-dependently increased after carbon ion beam and it was further increased when combined with CDDP. Carbon 127-133 caspase 3 Homo sapiens 31-40 29255307-2 2017 At the front face, the conductive functionalized carbon fiber paper (f-CFP) having oxygen-containing groups i.e., -OH and -COOH on its surface was placed face to face with the sulfur cathode serving as the first barrier accommodating the volume expansion during cycling process and the oxygen-containing groups can also adsorb the soluble LPSs via lithium bonds. Carbon 49-55 complement factor properdin Homo sapiens 71-74 29157608-3 2017 An alternative to C18 bonded phases, porous graphitic carbon has the ability to provide significant retention for both non-polar and polar analytes. Carbon 54-60 Bardet-Biedl syndrome 9 Homo sapiens 18-21 29157608-9 2017 As C18 bonded particles are widely, and successfully utilized for long gradient separations without issue of increasing peak width from longitudinal diffusion, this suggests that porous graphitic carbon should be amenable for long runtime gradient separations as well. Carbon 196-202 Bardet-Biedl syndrome 9 Homo sapiens 3-6 29132207-1 2017 Electron-beam (e-beam) deposition of carbon on a gold substrate yields a very flat (0.43 nm of root-mean-square roughness), amorphous carbon film consisting of a mixture of sp2- and sp3-hybridized carbon with sufficient conductivity to avoid ohmic potential error. Carbon 37-43 Sp2 transcription factor Homo sapiens 173-176 29132207-1 2017 Electron-beam (e-beam) deposition of carbon on a gold substrate yields a very flat (0.43 nm of root-mean-square roughness), amorphous carbon film consisting of a mixture of sp2- and sp3-hybridized carbon with sufficient conductivity to avoid ohmic potential error. Carbon 37-43 Sp3 transcription factor Homo sapiens 182-185 29132207-1 2017 Electron-beam (e-beam) deposition of carbon on a gold substrate yields a very flat (0.43 nm of root-mean-square roughness), amorphous carbon film consisting of a mixture of sp2- and sp3-hybridized carbon with sufficient conductivity to avoid ohmic potential error. Carbon 134-140 Sp2 transcription factor Homo sapiens 173-176 29132207-1 2017 Electron-beam (e-beam) deposition of carbon on a gold substrate yields a very flat (0.43 nm of root-mean-square roughness), amorphous carbon film consisting of a mixture of sp2- and sp3-hybridized carbon with sufficient conductivity to avoid ohmic potential error. Carbon 134-140 Sp3 transcription factor Homo sapiens 182-185 29132207-1 2017 Electron-beam (e-beam) deposition of carbon on a gold substrate yields a very flat (0.43 nm of root-mean-square roughness), amorphous carbon film consisting of a mixture of sp2- and sp3-hybridized carbon with sufficient conductivity to avoid ohmic potential error. Carbon 134-140 Sp2 transcription factor Homo sapiens 173-176 29132207-1 2017 Electron-beam (e-beam) deposition of carbon on a gold substrate yields a very flat (0.43 nm of root-mean-square roughness), amorphous carbon film consisting of a mixture of sp2- and sp3-hybridized carbon with sufficient conductivity to avoid ohmic potential error. Carbon 134-140 Sp3 transcription factor Homo sapiens 182-185 29137454-0 2017 Determination of Cancer Cell-Based pH-Sensitive Fluorescent Carbon Nanoparticles of Cross-Linked Polydopamine by Fluorescence Sensing of Alkaline Phosphatase Activity on Coated Surfaces and Aqueous Solution. Carbon 60-66 alkaline phosphatase, placental Homo sapiens 137-157 29172475-3 2017 The tridentate ligand shows the conversion of one diiminoisoindoline sp2 carbon to a sp3 carbon, which has been seen in the "helmet" and bicyclic phthalocyanines. Carbon 73-79 Sp2 transcription factor Homo sapiens 69-72 29172475-3 2017 The tridentate ligand shows the conversion of one diiminoisoindoline sp2 carbon to a sp3 carbon, which has been seen in the "helmet" and bicyclic phthalocyanines. Carbon 73-79 Sp3 transcription factor Homo sapiens 85-88 29172475-3 2017 The tridentate ligand shows the conversion of one diiminoisoindoline sp2 carbon to a sp3 carbon, which has been seen in the "helmet" and bicyclic phthalocyanines. Carbon 89-95 Sp2 transcription factor Homo sapiens 69-72 29172475-3 2017 The tridentate ligand shows the conversion of one diiminoisoindoline sp2 carbon to a sp3 carbon, which has been seen in the "helmet" and bicyclic phthalocyanines. Carbon 89-95 Sp3 transcription factor Homo sapiens 85-88 29594593-0 2017 An electrochemical aptamer-based assay for femtomolar determination of insulin using a screen printed electrode modified with mesoporous carbon and 1,3,6,8-pyrenetetrasulfonate. Carbon 137-143 insulin Homo sapiens 71-78 29164890-2 2017 alpha-Substituted 1,3-dicarbonyls reacted with vinylaziridines to give 2-methylenepyrrolidines bearing two adjacent sp3-carbon centers with moderate to excellent diastereoselectivity, while the reaction of alpha-unsubstituted 1,3-dicarbonyls afforded 2-pyrrolines in good yield. Carbon 24-30 Sp3 transcription factor Homo sapiens 116-119 29244867-1 2017 BACKGROUND: Folates and vitamin B12 are key nutrients in one-carbon metabolism and related diseases. Carbon 61-67 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 32-35 29166025-1 2017 Copper(II)-catalyzed cross-coupling of anilines, methyl arenes, and TMSN3 in the presence of tert-butylhydroperoxide at moderate temperature produced 2-aryl benzimidazoles via a tandem C(sp3/sp2)-H functionalization and C-N bond formations. Carbon 0-1 Sp2 transcription factor Homo sapiens 191-194 29399410-4 2018 In our experiments, poly(I:C) stimulated expression of both PD-L1 and PD-L2 on glioblastoma cells, and a pro-inflammatory secretome, including type I interferons (IFN) and chemokines CXCL9, CXCL10, CCL4 and CCL5. Carbon 27-28 C-X-C motif chemokine ligand 9 Homo sapiens 183-188 29416662-7 2018 In contrast to XN, isoXN showed much less effects on the kinase activity of IKKbeta and IkappaBalpha phosphorylation induced by XN in this study, suggesting that an electrophilic carbon center present in XN is critical for the anti-inflammation in colitis, especially inhibition of IKKbeta/NF-kappaB signaling pathway. Carbon 179-185 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus 88-100 29594532-9 2017 Graphical abstract Schematic of an inner filter effect based probe for alkaline phosphatase based on the use boron and nitrogen co-doped carbon dots (N/B-C-dots) modified with beta-cyclodextrin (beta-CD). Carbon 137-143 alkaline phosphatase, placental Homo sapiens 71-91 29032197-8 2017 STAT3 phosphorylation was induced by IL-22 and poly I:C. Carbon 54-55 signal transducer and activator of transcription 3 Homo sapiens 0-5 29032197-11 2017 In mouse lung cells in vivo, IL-22 suppressed poly I:C-induced upregulation of PD-L1. Carbon 53-54 CD274 antigen Mus musculus 79-84 29594532-0 2017 Inner filter effect based fluorometric determination of the activity of alkaline phosphatase by using carbon dots codoped with boron and nitrogen. Carbon 102-108 alkaline phosphatase, placental Homo sapiens 72-92 29083515-2 2017 The exo-selective asymmetric cycloaddition successfully regaled the construction of sp3 -rich and highly substituted natural-product-based spirooxindoles supporting many chiral centers, including contiguous all-carbon quaternary centers. Carbon 211-217 Sp3 transcription factor Homo sapiens 84-87 29200586-7 2017 At a bicarbonate concentration of 50 mmol L-1, current density increased to 10.7 A m-2 at an anode potential of -0.2 V. This increase in current density could be due to oxidation of formed acetate in addition to oxidation of hydrogen, or enhanced growth of hydrogen oxidizing bacteria due to the availability of acetate as carbon source. Carbon 7-13 immunoglobulin kappa variable 1-16 Homo sapiens 42-45 28988062-0 2017 Single-walled carbon nanotube: One specific inhibitor of cancer stem cells in osteosarcoma upon downregulation of the TGFbeta1 signaling. Carbon 14-20 transforming growth factor beta 1 Homo sapiens 118-126 28988062-4 2017 Here, we show that single-walled carbon nanotubes (SWCNTs), including unmodified SWCNT (SWCNT-Raw) and SWCNT-COOH, have the ability to specifically inhibit the process of TGFbeta1-induced OS cells dedifferentiation, prevent the stem cell phenotypes acquisition in OS cells and reduce the OSC viability under conditions which mimic the OS microenvironment. Carbon 33-39 transforming growth factor beta 1 Homo sapiens 171-179 29046224-0 2017 Reprint of: Impact of the corrin framework of vitamin B12 on the electrochemical carbon-skeleton rearrangement in comparison to an imine/oxime planar ligand; tuning selectivity in 1,2-migration of a functional group by controlling electrolysis potential. Carbon 81-87 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 54-57 29068229-7 2017 The alkyne-allene isomerization involves not only a torsional motion but also a bending of the molecule due to the sp to sp2 rehybridization of one of the alkyne carbon atoms. Carbon 162-168 Sp2 transcription factor Homo sapiens 121-124 29068203-0 2017 Rhodium-Catalyzed sp2 C-H Acetoxylation of N-Aryl Azaindoles/N-Heteroaryl Indolines. Carbon 8-9 Sp2 transcription factor Homo sapiens 18-21 29123019-2 2017 Herein we demonstrate that a photoredox-mediated hydrogen atom transfer protocol can efficiently and selectively install deuterium (D) and tritium (T) at alpha-amino sp3 carbon-hydrogen bonds in a single step, using isotopically labeled water (D2O or T2O) as the source of hydrogen isotope. Carbon 170-176 Sp3 transcription factor Homo sapiens 166-169 29125716-1 2017 Silicon doped tin oxide embedded porous carbon microspheres (Siy Sn1-y Ox @C) are synthesized. Carbon 40-46 solute carrier family 38 member 3 Homo sapiens 65-68 29125716-4 2017 Together with the conductive, porous carbon matrix that provides void space to accommodate the volume change of Sn during charge/discharge cycling, the novel Siy Sn1-y Ox @C exhibits excellent electrochemical performance. Carbon 37-43 solute carrier family 38 member 3 Homo sapiens 162-165 29236021-4 2017 The maximum ammonium removal of five times the amount of ammonium adsorbed was achieved when 1.0 muM OHHL was added at the C/N ratio of 7 (the bio-regeneration rate was up to 88.32%), which was 1.24-2.02 times the ammonium removal amount at C/N ratios of 3, 5, 9. Carbon 123-124 latexin Homo sapiens 97-100 29236021-4 2017 The maximum ammonium removal of five times the amount of ammonium adsorbed was achieved when 1.0 muM OHHL was added at the C/N ratio of 7 (the bio-regeneration rate was up to 88.32%), which was 1.24-2.02 times the ammonium removal amount at C/N ratios of 3, 5, 9. Carbon 241-242 latexin Homo sapiens 97-100 29236023-5 2017 Conversely, the carbon supply shortage, under low C/N ratios, increased N2O emission (0.040 mgN2O-N L-1), due to incomplete denitrification. Carbon 16-22 L1 cell adhesion molecule Homo sapiens 100-103 28958146-0 2017 Low-Temperature Single Carbon Nanotube Spectroscopy of sp3 Quantum Defects. Carbon 23-29 Sp3 transcription factor Homo sapiens 55-58 28958146-1 2017 Aiming to unravel the relationship between chemical configuration and electronic structure of sp3 defects of aryl-functionalized (6,5) single-walled carbon nanotubes (SWCNTs), we perform low-temperature single nanotube photoluminescence (PL) spectroscopy studies and correlate our observations with quantum chemistry simulations. Carbon 149-155 Sp3 transcription factor Homo sapiens 94-97 29086756-0 2017 Planar n-Si/PEDOT:PSS hybrid heterojunction solar cells utilizing functionalized carbon nanoparticles synthesized via simple pyrolysis route. Carbon 81-87 PSS Homo sapiens 18-21 29094932-4 2017 Herein, m-phenylenediamine (mPD) is used as a precursor to prepare carbon dots (named m-CDs) with highly fluorescent quantum yield (31.58% in water), and our investigation shows that the strong fluorescent emission of m-CDs can be effectively quenched by ClO-. Carbon 67-73 mevalonate (diphospho) decarboxylase Mus musculus 28-31 29125175-2 2017 The use of threonine derivatives with glycolaldehyde in the Petasis reaction has been studied and successfully applied in the process, achieving morpholines with a higher fraction of sp3 carbon atoms compared to blockbuster drugs. Carbon 187-193 Sp3 transcription factor Homo sapiens 183-186 29035032-4 2017 The prototype with the smallest reported overall diameter (~13 mum) is fabricated by successive coating of functional layers onto a single micro-carbon-fiber via a scalable process. Carbon 145-151 latexin Homo sapiens 63-66 29114650-0 2017 Electrochemical reactive oxygen species detection by cytochrome c immobilized with vertically aligned and electrochemically reduced graphene oxide on a glassy carbon electrode. Carbon 159-165 cytochrome c, somatic Homo sapiens 53-65 29114650-2 2017 The biosensor developed uses cytochrome c (Cyt c) modified glassy carbon electrodes coupled with electrochemically reduced graphene oxide (ErGO). Carbon 66-72 cytochrome c, somatic Homo sapiens 29-41 29114650-2 2017 The biosensor developed uses cytochrome c (Cyt c) modified glassy carbon electrodes coupled with electrochemically reduced graphene oxide (ErGO). Carbon 66-72 cytochrome c, somatic Homo sapiens 43-48 28578571-0 2017 Hypervalent-Iodine-Mediated Formation of Epoxides from Carbon(sp2)-Carbon(sp3) Single Bonds. Carbon 55-61 Sp2 transcription factor Homo sapiens 62-65 28578571-0 2017 Hypervalent-Iodine-Mediated Formation of Epoxides from Carbon(sp2)-Carbon(sp3) Single Bonds. Carbon 55-61 Sp3 transcription factor Homo sapiens 74-77 29040802-0 2017 Freezing Temperatures, Ice Nanotubes Structures, and Proton Ordering of TIP4P/ICE Water inside Single Wall Carbon Nanotubes. Carbon 107-113 carboxylesterase 2 Homo sapiens 78-81 29040802-7 2017 We have also analyzed the ice structure called "ice nanotube" that water forms inside the single walled carbon nanotubes when it freezes. Carbon 104-110 carboxylesterase 2 Homo sapiens 26-29 29040802-7 2017 We have also analyzed the ice structure called "ice nanotube" that water forms inside the single walled carbon nanotubes when it freezes. Carbon 104-110 carboxylesterase 2 Homo sapiens 48-51 29058889-4 2017 With a pre-existing chiral center at any of the backbone sp3-carbons, the reaction remained highly efficient and most importantly maintained excellent allene facial selectivities regardless of the substrate stereochemistry. Carbon 61-68 Sp3 transcription factor Homo sapiens 57-60 29040804-3 2017 We report a mechanochemical synthesis in which slow compression at room temperature under uniaxial stress can convert polycrystalline or single-crystal benzene monomer into single-crystalline packings of carbon nanothreads, a one-dimensional sp3 carbon nanomaterial. Carbon 204-210 Sp3 transcription factor Homo sapiens 242-245 29045145-1 2017 We study the ability of porphyrin molecules to cooperate upon adsorption on the sp2 curved surface of carbon nanotube. Carbon 102-108 Sp2 transcription factor Homo sapiens 80-83 29040804-3 2017 We report a mechanochemical synthesis in which slow compression at room temperature under uniaxial stress can convert polycrystalline or single-crystal benzene monomer into single-crystalline packings of carbon nanothreads, a one-dimensional sp3 carbon nanomaterial. Carbon 246-252 Sp3 transcription factor Homo sapiens 242-245 29141214-6 2017 Mthfr deletion or methionine treatment prevents NTDs in Gldc-null embryos by retention of one-carbon units within the folate cycle. Carbon 94-100 glycine decarboxylase Mus musculus 56-60 29028318-2 2017 In GASright dimers, such as glycophorin A (GpA), BNIP3, and members of the ErbB family, the backbones of the helices are in contact, and they invariably display networks of 4 to 8 weak hydrogen bonds between Calpha-H carbon donors and carbonyl acceptors on opposing helices (Calpha-H O C hydrogen bonds). Carbon 217-223 glycophorin A (MNS blood group) Homo sapiens 28-41 29028318-2 2017 In GASright dimers, such as glycophorin A (GpA), BNIP3, and members of the ErbB family, the backbones of the helices are in contact, and they invariably display networks of 4 to 8 weak hydrogen bonds between Calpha-H carbon donors and carbonyl acceptors on opposing helices (Calpha-H O C hydrogen bonds). Carbon 217-223 glycophorin A (MNS blood group) Homo sapiens 43-46 29028318-2 2017 In GASright dimers, such as glycophorin A (GpA), BNIP3, and members of the ErbB family, the backbones of the helices are in contact, and they invariably display networks of 4 to 8 weak hydrogen bonds between Calpha-H carbon donors and carbonyl acceptors on opposing helices (Calpha-H O C hydrogen bonds). Carbon 217-223 BCL2 interacting protein 3 Homo sapiens 49-54 28916726-0 2017 The NQO1 bioactivatable drug, beta-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism. Carbon 135-141 NAD(P)H quinone dehydrogenase 1 Homo sapiens 4-8 29112861-0 2017 Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf). Carbon 11-17 TSC complex subunit 1 Homo sapiens 91-107 29112861-0 2017 Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf). Carbon 11-17 cyclin dependent kinase inhibitor 2A Homo sapiens 113-119 29112861-0 2017 Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf). Carbon 11-17 cyclin dependent kinase inhibitor 2A Homo sapiens 121-130 28916726-0 2017 The NQO1 bioactivatable drug, beta-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism. Carbon 135-141 NAD(P)H quinone dehydrogenase 1 Homo sapiens 72-76 28994579-0 2017 Dual Amplification Fluorescence Assay for Alpha Fetal Protein Utilizing Immunohybridization Chain Reaction and Metal-Enhanced Fluorescence of Carbon Nanodots. Carbon 142-148 alpha fetoprotein Homo sapiens 42-61 28942589-8 2017 Granular activated carbon (GAC) was used as an effective post-treatment step and could achieve 89.1% UV absorbance reduction with 40 g L-1. Carbon 19-25 immunoglobulin kappa variable 1-16 Homo sapiens 135-138 28985002-2 2017 Compared with 12-pi-electron fluorene, a carbon-bridged biphenylene with an axial symmetry, indenoindene, a carbon-bridged E-stilbene with a centrosymmetry, shows elongated pi-conjugation with 14 pi-electrons and one more sp3 carbon bridge, which may increase the tunability of electronic structure and film morphology. Carbon 41-47 Sp3 transcription factor Homo sapiens 222-225 28985002-2 2017 Compared with 12-pi-electron fluorene, a carbon-bridged biphenylene with an axial symmetry, indenoindene, a carbon-bridged E-stilbene with a centrosymmetry, shows elongated pi-conjugation with 14 pi-electrons and one more sp3 carbon bridge, which may increase the tunability of electronic structure and film morphology. Carbon 108-114 Sp3 transcription factor Homo sapiens 222-225 28985002-2 2017 Compared with 12-pi-electron fluorene, a carbon-bridged biphenylene with an axial symmetry, indenoindene, a carbon-bridged E-stilbene with a centrosymmetry, shows elongated pi-conjugation with 14 pi-electrons and one more sp3 carbon bridge, which may increase the tunability of electronic structure and film morphology. Carbon 108-114 Sp3 transcription factor Homo sapiens 222-225 28778043-0 2017 Rapid and efficient removal of Pb(II) from aqueous solutions using biomass-derived activated carbon with humic acid in-situ modification. Carbon 93-99 submaxillary gland androgen regulated protein 3B Homo sapiens 31-37 28778043-1 2017 This study developed an humic acid (HA) in-situ modified activated carbon adsorbent (AC-HA) for the rapid and efficient removal of Pb(II) from aqueous media, and adsorption mechanisms are discussed. Carbon 67-73 submaxillary gland androgen regulated protein 3B Homo sapiens 131-137 28778043-6 2017 The superior performance of AC-HA was attributed to the HA modification, which contains numbers of groups and has a strong pi-pi interaction binding energy with AC and Pb(II) species. Carbon 28-30 submaxillary gland androgen regulated protein 3B Homo sapiens 168-174 30197786-6 2017 Particularly, accumulation of aromatic carbons with strong styrene-like molecular signatures on PEPs is associated with formation of semivolatile heavier aromatic species (i.e., PAHs). Carbon 39-46 leucine aminopeptidase 3 Homo sapiens 96-100 28920168-0 2017 The online measured black carbon aerosol and source orientations in the Nam Co region, Tibet. Carbon 26-32 SH3 and cysteine rich domain 3 Homo sapiens 72-75 28544022-1 2017 The ideal graphene is a one-atom thick single layer of carbon atoms having sp2 hybridation in hexagonal arrangement. Carbon 55-61 Sp2 transcription factor Homo sapiens 75-78 28884369-0 2017 Carbon Nanotube Fiber Ionization Mass Spectrometry: A Fundamental Study of a Multi-Walled Carbon Nanotube Functionalized Corona Discharge Pin for Polycyclic Aromatic Hydrocarbons Analysis. Carbon 0-6 dynein light chain LC8-type 1 Homo sapiens 138-141 28884369-0 2017 Carbon Nanotube Fiber Ionization Mass Spectrometry: A Fundamental Study of a Multi-Walled Carbon Nanotube Functionalized Corona Discharge Pin for Polycyclic Aromatic Hydrocarbons Analysis. Carbon 90-96 dynein light chain LC8-type 1 Homo sapiens 138-141 28735209-10 2017 An index for carbon availability related to NO3--N removal was developed. Carbon 13-19 NBL1, DAN family BMP antagonist Homo sapiens 44-47 29101519-6 2017 The simulations revealed that 6-carbons linker is the optimal one, whereas shorter or longer linkers resulted in decreased PLA2-mediated activation. Carbon 32-39 phospholipase A2 group IB Homo sapiens 123-127 28482074-0 2017 Carbon ion irradiation abrogates Lin28B-induced X-ray resistance in melanoma cells. Carbon 0-6 lin-28 homolog B Homo sapiens 33-39 28482074-5 2017 Interestingly, Lin28B-overexpressed melanoma cells were more resistant to X-ray irradiation than control cells, and Lin28B-induced radioresistance was abolished after carbon ion irradiation. Carbon 167-173 lin-28 homolog B Homo sapiens 116-122 28968774-5 2017 Among these, associations with the levels of CRP (beta= -0.53; P = 0.01) and CCL15/MIP-1D (beta = 0.20; P = 0.02) were observed in workers exposed to DEE and with increasing elemental carbon exposure levels (Ptrends <0.05) in multivariable linear regression models. Carbon 184-190 C-reactive protein Homo sapiens 45-48 28887418-9 2017 Our results provide new information regarding the function of the lmo0325-lmo0327 locus in L. monocytogenes and link it to the expression of chitinolytic activity.IMPORTANCE Many bacteria from terrestrial and marine environments express chitinase activities enabling them to utilize chitin as the sole source of carbon and nitrogen. Carbon 312-318 lmo0327 Listeria monocytogenes EGD-e 74-81 29168708-0 2017 Preparation of magnetic carbon/Fe3O4 supported zero-valent iron composites and their application in Pb(II) removal from aqueous solutions. Carbon 24-30 submaxillary gland androgen regulated protein 3B Homo sapiens 100-106 28745302-1 2017 Similar to graphene, carbon nanotubes are materials made of pure carbon in its sp2 form. Carbon 21-27 Sp2 transcription factor Homo sapiens 79-82 29079776-9 2017 In concert with GCN2, TOR allows photo-autotrophic eukaryotes to coordinate the fluxes of carbon, nitrogen, and sulfur for efficient cysteine biosynthesis under varying external nutrient supply. Carbon 90-96 target of rapamycin Arabidopsis thaliana 22-25 28745302-1 2017 Similar to graphene, carbon nanotubes are materials made of pure carbon in its sp2 form. Carbon 65-71 Sp2 transcription factor Homo sapiens 79-82 28953352-8 2017 Besides, it also provides a detailed and insightful understanding of the sp2 carbon catalytic growth, which is vital in developing efficient and practical graphene synthetic routes. Carbon 77-83 Sp2 transcription factor Homo sapiens 73-76 28931280-3 2017 Herein, we describe sp3-stereogenic carbon-bearing molecules that dynamically isomerize, interconverting between enantiomers without cleavage of a constituent bond, nor through remote functional group migration. Carbon 36-42 Sp3 transcription factor Homo sapiens 20-23 29262618-1 2017 Ceramide synthase 1 (CERS1) is the most highly expressed CERS in the central nervous system, and ceramide with an 18-carbon-containing fatty acid chain (C18-ceramide) in the brain plays important roles in signaling and sphingolipid development. Carbon 117-123 ceramide synthase 1 Homo sapiens 0-19 29031295-2 2017 Here we report the first study on the development and validation of a novel disposable competitive amperometric immunosensor for determination of p53 protein at subnanomolar levels, based on p53 immobilization on gold nanoparticles/carbon nanotubes modified screen-printed carbon electrodes. Carbon 273-279 tumor protein p53 Homo sapiens 191-194 29031295-0 2017 Competitive amperometric immunosensor for determination of p53 protein in urine with carbon nanotubes/gold nanoparticles screen-printed electrodes: A potential rapid and noninvasive screening tool for early diagnosis of urinary tract carcinoma. Carbon 85-91 tumor protein p53 Homo sapiens 59-62 29031295-2 2017 Here we report the first study on the development and validation of a novel disposable competitive amperometric immunosensor for determination of p53 protein at subnanomolar levels, based on p53 immobilization on gold nanoparticles/carbon nanotubes modified screen-printed carbon electrodes. Carbon 232-238 tumor protein p53 Homo sapiens 146-149 29031295-2 2017 Here we report the first study on the development and validation of a novel disposable competitive amperometric immunosensor for determination of p53 protein at subnanomolar levels, based on p53 immobilization on gold nanoparticles/carbon nanotubes modified screen-printed carbon electrodes. Carbon 273-279 tumor protein p53 Homo sapiens 146-149 29262618-1 2017 Ceramide synthase 1 (CERS1) is the most highly expressed CERS in the central nervous system, and ceramide with an 18-carbon-containing fatty acid chain (C18-ceramide) in the brain plays important roles in signaling and sphingolipid development. Carbon 117-123 ceramide synthase 1 Homo sapiens 21-26 28728113-1 2017 A new amperometric hydrogen peroxide enzyme inhibition biosensor for the indirect determination of toxic mercury ions, Hg2+, based on catalase immobilized on a glassy carbon electrode surface by cross-linking with glutaraldehyde and bovine serum albumin, is reported. Carbon 167-173 catalase Homo sapiens 134-142 28937736-0 2017 The Detrimental Effects of Carbon Additives in Li10GeP2S12-Based Solid-State Batteries. Carbon 27-33 granulin precursor Homo sapiens 51-54 28930437-5 2017 The most commonly encountered structures, C- and N-metalated nitriles, have either sp3 or sp2 hybridization at the nucleophilic carbon, which essentially translates into two distinct organometallic species with similar but nonidentical stereoselectivity, regioselectivity, and reactivity preferences. Carbon 42-43 Sp3 transcription factor Homo sapiens 83-86 28930437-5 2017 The most commonly encountered structures, C- and N-metalated nitriles, have either sp3 or sp2 hybridization at the nucleophilic carbon, which essentially translates into two distinct organometallic species with similar but nonidentical stereoselectivity, regioselectivity, and reactivity preferences. Carbon 42-43 Sp2 transcription factor Homo sapiens 90-93 28930437-5 2017 The most commonly encountered structures, C- and N-metalated nitriles, have either sp3 or sp2 hybridization at the nucleophilic carbon, which essentially translates into two distinct organometallic species with similar but nonidentical stereoselectivity, regioselectivity, and reactivity preferences. Carbon 128-134 Sp3 transcription factor Homo sapiens 83-86 28930437-5 2017 The most commonly encountered structures, C- and N-metalated nitriles, have either sp3 or sp2 hybridization at the nucleophilic carbon, which essentially translates into two distinct organometallic species with similar but nonidentical stereoselectivity, regioselectivity, and reactivity preferences. Carbon 128-134 Sp2 transcription factor Homo sapiens 90-93 28525853-0 2017 Photoelectrochemical sensitive detection of insulin based on CdS/polydopamine co-sensitized WO3 nanorod and signal amplification of carbon nanotubes@polydopamine. Carbon 132-138 insulin Homo sapiens 44-51 28525853-1 2017 An ultrasensitive photoelectrochemical sandwich immunosensor was designed for detection of insulin based on WO3/CdS/polydopamine (WO3/CdS/PDA) co-sensitized and PDA@carbon nanotubes (PDA@CNT) conjugates for signal amplification. Carbon 165-171 insulin Homo sapiens 91-98 28627471-6 2017 The rate and degree of PLA2-mediated activation were highly dependent on the linker length; 2- and 4-carbon linker conjugates were activated to lower extent than the 6-carbon conjugate, and longer linker again decreased the affinity towards PLA2. Carbon 101-107 phospholipase A2 group IB Homo sapiens 23-27 28627471-6 2017 The rate and degree of PLA2-mediated activation were highly dependent on the linker length; 2- and 4-carbon linker conjugates were activated to lower extent than the 6-carbon conjugate, and longer linker again decreased the affinity towards PLA2. Carbon 101-107 phospholipase A2 group IB Homo sapiens 241-245 28627471-6 2017 The rate and degree of PLA2-mediated activation were highly dependent on the linker length; 2- and 4-carbon linker conjugates were activated to lower extent than the 6-carbon conjugate, and longer linker again decreased the affinity towards PLA2. Carbon 168-174 phospholipase A2 group IB Homo sapiens 23-27 28627471-6 2017 The rate and degree of PLA2-mediated activation were highly dependent on the linker length; 2- and 4-carbon linker conjugates were activated to lower extent than the 6-carbon conjugate, and longer linker again decreased the affinity towards PLA2. Carbon 168-174 phospholipase A2 group IB Homo sapiens 241-245 28627471-7 2017 The 6-carbon linker conjugate was found to be the optimal and released ~95% of the free drug after incubation with PLA2, whereas only ~20% were delivered by the 2-carbon linker prodrug. Carbon 6-12 phospholipase A2 group IB Homo sapiens 115-119 29019049-2 2017 Contrary to sp2-bonded carbon, relative intensities of the bands do not depend on the 458- and 257-nm excitation wavelengths, and a halfwidth and the intensity of the 1600 cm-1 band does not change visibly under pressure at least up to 50 GPa. Carbon 23-29 Sp2 transcription factor Homo sapiens 12-15 28927267-5 2017 The segregated sp2 carbon network serves as the backbone to maintain the structural stability of the lattice. Carbon 19-25 Sp2 transcription factor Homo sapiens 15-18 28934852-2 2017 Transformations employ [B(pin)]2-methane as a conjunctive reagent, resulting in the formation of two C-C bonds at a single carbon center bearing a C(sp3) organoboron functional group. Carbon 123-129 dynein light chain LC8-type 1 Homo sapiens 26-29 28944818-1 2017 The methodology of direct C(sp2)-H functionalization has for the first time been applied as an efficient and advanced approach to carry out C-H/C-H coupling of 2H-imidazole 1-oxides and pyrroles. Carbon 140-141 Sp2 transcription factor Homo sapiens 26-31 28609571-3 2017 Another way to achieve such control is to take advantage of the specific reactivity of heteroatoms placed within the sp2 -carbon framework. Carbon 122-128 Sp2 transcription factor Homo sapiens 117-120 28858498-1 2017 The secondary metabolites that comprise the diterpenoid alkaloids are categorized into C18, C19, and C20 families depending on the number of contiguous carbon atoms that constitute their central framework. Carbon 152-158 Bardet-Biedl syndrome 9 Homo sapiens 87-90 28956615-0 2017 Copper-Catalyzed Synthesis of Indol-3-yl alpha-(Difluoromethyl)-alpha-(trifluoromethyl)carbinols: Construction of Difluoromethylated sp3 Carbon Centers. Carbon 137-143 Sp3 transcription factor Homo sapiens 133-136 28956615-4 2017 This strategy provides a general synthetic method for ready construction of difluoromethylated sp3 carbon centers. Carbon 99-105 Sp3 transcription factor Homo sapiens 95-98 28936873-8 2017 Finally, the products of Rox(III) degradation were identified as As(III) and 2-nitrohydroquinone, demonstrating that ArsI is a dioxygenase that incorporates one oxygen atom from dioxygen into the carbon and the other to the arsenic to catalyze cleavage of the C-As bond. Carbon 196-202 MAX network transcriptional repressor Homo sapiens 25-28 28876920-7 2017 Our results suggest that seasonal influxes of O2 and NO3- may cause only localized mobilization of U without leading to export of U from the reducing sediments when ample organic carbon is present. Carbon 179-185 NBL1, DAN family BMP antagonist Homo sapiens 53-56 28967864-0 2017 Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer. Carbon 77-83 NFE2 like bZIP transcription factor 2 Homo sapiens 18-22 28967864-6 2017 Cancers with genetic or pharmacological activation of the NRF2 antioxidant pathway have a metabolic imbalance between supporting increased antioxidant capacity over central carbon metabolism, which can be therapeutically exploited. Carbon 173-179 NFE2 like bZIP transcription factor 2 Homo sapiens 58-62 28868218-3 2017 This study aims to improve the secretion of recombinant CRP by Pichia pastoris via optimizing signal peptides, promoters and carbon sources. Carbon 125-131 C-reactive protein Homo sapiens 56-59 28868218-8 2017 Subsequently, different carbon sources and at different concentrations were used to further improve the secretion of CRP. Carbon 24-30 C-reactive protein Homo sapiens 117-120 28534297-1 2017 A biofunctionalized reduced graphene oxide (rGO)-modified screen-printed carbon electrode (SPCE) was constructed as an immunosensor for C-reactive protein (CRP) detection, a biomarker released in early stage acute myocardial infarction. Carbon 73-79 C-reactive protein Homo sapiens 136-154 28534297-1 2017 A biofunctionalized reduced graphene oxide (rGO)-modified screen-printed carbon electrode (SPCE) was constructed as an immunosensor for C-reactive protein (CRP) detection, a biomarker released in early stage acute myocardial infarction. Carbon 73-79 C-reactive protein Homo sapiens 156-159 28666100-2 2017 Here, multifunctional polymer-coated carbon nanodots with an interleukin-6 (IL-6) fragment peptide for receptor-targeting (pCDPI) were prepared for drug delivery. Carbon 37-43 interleukin 6 Mus musculus 61-74 28666100-2 2017 Here, multifunctional polymer-coated carbon nanodots with an interleukin-6 (IL-6) fragment peptide for receptor-targeting (pCDPI) were prepared for drug delivery. Carbon 37-43 interleukin 6 Mus musculus 76-80 28871517-11 2017 Organic carbon showed a significant positive correlation with the activities of alkaline (r = 0.668; P < 0.05) and acid phosphatase (r = 0.668; P < 0.05) however not with catalase and dehydrogenases. Carbon 8-14 catalase Homo sapiens 177-185 28646765-4 2017 All PCB congeners were positively correlated with total organic carbon (TOC) concentrations. Carbon 64-70 pyruvate carboxylase Homo sapiens 4-7 28672722-1 2017 The electro-Fenton oxidation of a concentrate from reverse osmosis of a sanitary landfill leachate, with an initial chemical oxygen demand (COD) of 42 g L-1, was carried out using a carbon-felt cathode and a boron doped diamond anode. Carbon 182-188 immunoglobulin kappa variable 1-16 Homo sapiens 153-156 28922741-1 2017 Sialic acid acetylesterase (SIAE) removes acetyl moieties from the carbon 9 and 4 hydroxyl groups of sialic acid and recently a debate has been opened on its association to autoimmunity. Carbon 67-73 sialic acid acetylesterase Danio rerio 0-26 28640985-4 2017 Here, we report that the interaction between PSAP and PGRN requires the linker region of saposin B and C (BC linker). Carbon 103-104 granulin precursor Homo sapiens 54-58 28802222-0 2017 Impact of the corrin framework of vitamin B12 on the electrochemical carbon-skeleton rearrangement in comparison to an imine/oxime planar ligand; tuning selectivity in 1,2-migration of a functional group by controlling electrolysis potential. Carbon 69-75 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 42-45 28957510-6 2017 While many of the adaptive mutations occur in genes that encode proteins with known roles in glucose sensing and transport, we discover mutations in genes with no canonical role in carbon utilization (IPT1 and MOT3), as well as identify novel dominant mutations in glucose signal transducers thought to only accumulate recessive mutations in carbon limited environments (MTH1 and RGT1). Carbon 342-348 inositolphosphotransferase Saccharomyces cerevisiae S288C 201-205 28814602-0 2017 Carbon Nanoparticles Inhibit the Antimicrobial Activities of the Human Cathelicidin LL-37 through Structural Alteration. Carbon 0-6 cathelicidin antimicrobial peptide Homo sapiens 84-89 28814602-6 2017 This study investigated whether the potent antibacterial and antiviral functions of LL-37 were inhibited by exposure to, and interaction with, carbon nanoparticles, together with characterizing the nature of the interaction. Carbon 143-149 cathelicidin antimicrobial peptide Homo sapiens 84-89 28543370-1 2017 Rubisco activase (RCA) is an important enzyme that can catalyze the carboxylation and oxygenation activities of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), which is involved in the photosynthetic carbon reduction cycle. Carbon 211-217 ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic Cucumis sativus 18-21 28901368-3 2017 Furthermore, the 1-methyl group reacts to become involved in C-C bonds involving only sp3-hybridised carbon atoms. Carbon 101-107 Sp3 transcription factor Homo sapiens 86-89 29034878-1 2017 Recently, a new type of limb-girdle muscular dystrophy (LGMD type 2Z) has been identified due to a missense mutation in POGLUT1 (protein O-glucosyltransferase-Rumi), an enzyme capable of adding glucose to a distinct serine residue of epidermal growth factor-like repeats containing a C-X-S-X-(P/A)-C consensus sequence such as Notch receptors. Carbon 284-285 protein O-glucosyltransferase 1 Homo sapiens 120-127 29034878-1 2017 Recently, a new type of limb-girdle muscular dystrophy (LGMD type 2Z) has been identified due to a missense mutation in POGLUT1 (protein O-glucosyltransferase-Rumi), an enzyme capable of adding glucose to a distinct serine residue of epidermal growth factor-like repeats containing a C-X-S-X-(P/A)-C consensus sequence such as Notch receptors. Carbon 284-285 protein O-glucosyltransferase 1 Homo sapiens 159-163 28658609-7 2017 Expression of the genes involved in cuticle biosynthesis indicated that LIN5 influences the biosynthesis of components of the cuticle, indicating that this process is coupled to sugar uploading via a mechanism which links carbon supply with the capacity for fruit expansion. Carbon 222-228 beta-fructofuranosidase Solanum lycopersicum 72-76 28858489-2 2017 In the last years, some N-heterocyclic carbene (NHC) complexes of high-valent d0 transition-metal halides have been structurally characterized, showing a significant short distance between the carbene carbon and the cis-halide ligands (Clax). Carbon 201-207 high mobility group nucleosomal binding domain 4 Homo sapiens 48-51 28782276-4 2017 This unprecedented feature was confirmed by reactions with two electrophiles (PhNCS and CS2 ), resulting in two types of C=C coupling reactions. Carbon 81-82 chorionic somatomammotropin hormone 2 Homo sapiens 88-91 28733286-0 2017 Regulator LdhR and d-Lactate Dehydrogenase LdhA of Burkholderia multivorans Play Roles in Carbon Overflow and in Planktonic Cellular Aggregate Formation. Carbon 90-96 lactate dehydrogenase A Homo sapiens 43-47 28683158-1 2017 A one-dimensional nanostructure with sp3 -hybridized carbon atoms, namely, poly[5]asterane (PA), is predicted by means of electronic structure calculations and reactive molecular dynamics simulations. Carbon 53-59 Sp3 transcription factor Homo sapiens 37-40 28849923-4 2017 The combination of Ni catalysis with (Bpin)2/K3PO4 as terminal reductant promoted the efficient C(sp2)-C(sp3) formation especially the generation of all-carbon quaternary centers with high chemoselectivity. Carbon 153-159 Sp2 transcription factor Homo sapiens 96-101 28916799-2 2017 Three MeOH molecules should be connected with PIP-C forming stable PIP-C-MeOH complex in the S0 state. Carbon 50-51 prolactin induced protein Homo sapiens 46-49 28916799-2 2017 Three MeOH molecules should be connected with PIP-C forming stable PIP-C-MeOH complex in the S0 state. Carbon 50-51 prolactin induced protein Homo sapiens 67-70 28916799-7 2017 As a whole, this work not only put forward a new excited state mechanism for PIP-C system, but also compensates for the defects about mechanism in previous experiment. Carbon 81-82 prolactin induced protein Homo sapiens 77-80 28568053-0 2017 Low vitamin B12 increases risk of gastric cancer: A prospective study of one-carbon metabolism nutrients and risk of upper gastrointestinal tract cancer. Carbon 77-83 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 12-15 28370459-1 2017 A net insertion of an unactivated, internal alkyne into a sp2 -sp3 C-C bond of simple benzylic alcohols was achieved using the rearrangement of a highly reactive vinyl cation intermediate to a stabilized allyl cation as the driving force for an unusual 1,3-carbon shift reaction. Carbon 257-263 Sp2 transcription factor Homo sapiens 58-61 28825760-4 2017 Interestingly, the calcination of Cu-COP-1 and Cu-COP-5 at 330 C produced pure CuNPs, whereas Cu-COP-2, Cu-COP-3, Cu-COP-4 and Cu-COP-7 gave CuONPs encapsulated by carbon matrix. Carbon 165-171 COP1 E3 ubiquitin ligase Homo sapiens 37-42 28665485-6 2017 The zigzag edges of sp2 carbon planes are shown to play a key role in these reactions. Carbon 24-30 Sp2 transcription factor Homo sapiens 20-23 29965254-4 2017 When the dosage of PAC was 20 mg L-1 and the adsorption time ranged from 10 to 30 min, the removal rates of 3.30 mg L-1 dissolved organic carbon were 20.7%-31.9% for intracellular organic matter (IOM) and 12.6%-19.0% for extracellular organic matter (EOM). Carbon 138-144 immunoglobulin kappa variable 1-16 Homo sapiens 33-36 29965254-4 2017 When the dosage of PAC was 20 mg L-1 and the adsorption time ranged from 10 to 30 min, the removal rates of 3.30 mg L-1 dissolved organic carbon were 20.7%-31.9% for intracellular organic matter (IOM) and 12.6%-19.0% for extracellular organic matter (EOM). Carbon 138-144 immunoglobulin kappa variable 1-16 Homo sapiens 116-119 28370459-1 2017 A net insertion of an unactivated, internal alkyne into a sp2 -sp3 C-C bond of simple benzylic alcohols was achieved using the rearrangement of a highly reactive vinyl cation intermediate to a stabilized allyl cation as the driving force for an unusual 1,3-carbon shift reaction. Carbon 257-263 Sp3 transcription factor Homo sapiens 63-66 27232191-1 2017 A group of homologous nucleic acid modification enzymes called Dnmt2, Trdmt1, Pmt1, DnmA, and Ehmet in different model organisms catalyze the transfer of a methyl group from the cofactor S-adenosyl-methionine (SAM) to the carbon-5 of cytosine residues. Carbon 222-228 tRNA aspartic acid methyltransferase 1 Homo sapiens 63-68 28806526-3 2017 In this device, p-type PbS quantum dots-modified glass carbon electrode (GCE) served as the photocathode for the reduction of p-NP under photoirradiation while graphene-modified GCE was employed as the anode for the oxidation of ascorbic acid. Carbon 55-61 purine nucleoside phosphorylase Homo sapiens 126-130 28805482-3 2017 Here we describe that cyclophilin 20-3 (CYP20-3), a binding protein of (+)-12-oxo-phytodienoic acid (OPDA), crisscrosses stress responses with light-dependent redox reactions, which fine-tunes the activity of key enzymes in the plastid photosynthetic carbon assimilation and sulfur assimilation pathways. Carbon 251-257 peptidylprolyl isomerase H Homo sapiens 40-45 28501644-5 2017 The torsion angle of the PCB congeners was also shown to be an extremely important factor to be able to use activated carbon as part of the remediation process. Carbon 118-124 pyruvate carboxylase Homo sapiens 25-28 27232191-1 2017 A group of homologous nucleic acid modification enzymes called Dnmt2, Trdmt1, Pmt1, DnmA, and Ehmet in different model organisms catalyze the transfer of a methyl group from the cofactor S-adenosyl-methionine (SAM) to the carbon-5 of cytosine residues. Carbon 222-228 tRNA aspartic acid methyltransferase 1 Homo sapiens 70-76 28647381-8 2017 Montelukast significantly attenuated the poly I:C-induced increase in the number of eosinophils and levels of IL-13, IL-9, and CCL3 in BALF and airway hyperresponsiveness in both the reliever and controller models. Carbon 48-49 interleukin 13 Mus musculus 110-115 28751572-8 2017 However, black carbon, sulfate, and nitrogen oxides were negatively associated with fibrinogen, and sulfate was negatively associated with tumor necrosis factor alpha. Carbon 15-21 fibrinogen beta chain Homo sapiens 84-94 28585894-4 2017 Furthermore, the peak positions for methylene wagging vibration differed depending on the carbon number of the fatty acid, so that information from the ATR SEIRA spectra makes it possible to identify substances coating silver nanoparticles. Carbon 90-96 ATR serine/threonine kinase Homo sapiens 152-155 28667386-0 2017 A label-free electrochemical biosensor based on tubulin immobilized on gold nanoparticle/glassy carbon electrode for the determination of vinblastine. Carbon 96-102 TUB bipartite transcription factor Homo sapiens 48-55 28809129-3 2017 Further perturbations to one carbon metabolism, such as reduced vitamin B12 levels via the use of nitrous oxide for sedation during childhood ALL treatment, may increase neurotoxicity risk. Carbon 29-35 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 72-75 28648976-10 2017 Loading of BM cells with poly(I:C), EAC lysate or hTERT-mRNA could induce the expression of CD11b and CD11c. Carbon 32-33 integrin alpha M Mus musculus 92-97 28852020-3 2017 Here we show a carbon-based nanomaterial nanodiamond (ND) that carried paclitaxel (PTX), a microtubule inhibitor, and cetuximab (Cet), a specific monoclonal antibody against epidermal growth factor receptor (EGFR), inducing mitotic catastrophe and tumor inhibition in human colorectal cancer (CRC). Carbon 15-21 epidermal growth factor receptor Homo sapiens 174-206 28481475-6 2017 In contrast, the carbon decomposed from the sucrose has a high portion of sp3 hybridized and crosslinked carbon atoms with high reactivity, leading to the formation of MoC with full occupation of interstitial sites by carbon atoms. Carbon 17-23 Sp3 transcription factor Homo sapiens 74-77 28692755-3 2017 Here, this work reports a facile single-walled carbon nanotube (SWCNT) percolating strategy for efficiently maximizing the electrochemical performances of gallium chalcogenide (GaX, X = S or Se). Carbon 47-53 mesenchyme homeobox 2 Homo sapiens 177-180 28852020-3 2017 Here we show a carbon-based nanomaterial nanodiamond (ND) that carried paclitaxel (PTX), a microtubule inhibitor, and cetuximab (Cet), a specific monoclonal antibody against epidermal growth factor receptor (EGFR), inducing mitotic catastrophe and tumor inhibition in human colorectal cancer (CRC). Carbon 15-21 epidermal growth factor receptor Homo sapiens 208-212 28894419-9 2017 In this study, black and inactive compounds are found to have not only higher solubility, but also a higher number of chiral centers, sp3 carbon atoms and aliphatic rings. Carbon 138-144 Sp3 transcription factor Homo sapiens 134-137 28842673-1 2017 There have been a number of theoretical and experimental studies on tensile properties of carbon nanotubes (CNT), reporting the Young"s modulus of the individual CNT up to 1 TPa. Carbon 90-96 plasminogen activator, tissue type Homo sapiens 174-177 28734356-5 2017 The Pd-Cu NWs not only provide a large active surface area (0.268 +- 0.01) cm2 for the immobilization of AChE, which was approximately 3.8 times higher than the bare glass carbon electrode, but also exhibit excellent electro-catalytic activity and remarkable electron mobility. Carbon 172-178 acetylcholinesterase (Cartwright blood group) Homo sapiens 105-109 28395163-6 2017 This aGO1 modified screen printed carbon electrode (SPCE) was furnished the sensitive detection of HQ and CC with linear concentration range from 1 to 312muM and 1 to 350muM. Carbon 34-40 argonaute RISC component 1 Homo sapiens 5-9 28649795-3 2017 The reaction, formally a nucleophilic substitution at an sp2 carbon atom, allows the direct regioselective incorporation of mono-, di-, tri-, and tetrasubstituted olefins at the alpha-carbon of amino acid derivatives. Carbon 61-67 Sp2 transcription factor Homo sapiens 57-60 28649795-3 2017 The reaction, formally a nucleophilic substitution at an sp2 carbon atom, allows the direct regioselective incorporation of mono-, di-, tri-, and tetrasubstituted olefins at the alpha-carbon of amino acid derivatives. Carbon 184-190 Sp2 transcription factor Homo sapiens 57-60 28691245-2 2017 Cl-GDY is endowed with a unique pi-conjugated carbon skeleton with expanded pore size in two dimensions, having graphdiyne-like sp- and sp2 - hybridized carbon atoms. Carbon 46-52 Sp2 transcription factor Homo sapiens 136-139 28818940-0 2017 Two-dimensional sp2 carbon-conjugated covalent organic frameworks. Carbon 20-26 Sp2 transcription factor Homo sapiens 16-19 28818940-1 2017 We synthesized a two-dimensional (2D) crystalline covalent organic framework (sp2c-COF) that was designed to be fully pi-conjugated and constructed from all sp2 carbons by C=C condensation reactions of tetrakis(4-formylphenyl)pyrene and 1,4-phenylenediacetonitrile. Carbon 161-168 Sp2 transcription factor Homo sapiens 78-81 28818940-1 2017 We synthesized a two-dimensional (2D) crystalline covalent organic framework (sp2c-COF) that was designed to be fully pi-conjugated and constructed from all sp2 carbons by C=C condensation reactions of tetrakis(4-formylphenyl)pyrene and 1,4-phenylenediacetonitrile. Carbon 83-84 Sp2 transcription factor Homo sapiens 78-81 28818940-1 2017 We synthesized a two-dimensional (2D) crystalline covalent organic framework (sp2c-COF) that was designed to be fully pi-conjugated and constructed from all sp2 carbons by C=C condensation reactions of tetrakis(4-formylphenyl)pyrene and 1,4-phenylenediacetonitrile. Carbon 172-173 Sp2 transcription factor Homo sapiens 78-81 28818940-5 2017 The sp2 carbon framework induces ferromagnetic phase transition to develop spin-spin coherence and align spins unidirectionally across the material. Carbon 8-14 Sp2 transcription factor Homo sapiens 4-7 28671468-8 2017 For the intact PKCalpha and PKCdelta, the shortest DAG-lactone dimer had similar affinity to the monomer and affinity decreased progressively up to the 16-carbon linker. Carbon 155-161 protein kinase C alpha Homo sapiens 15-23 28693727-1 2017 An electrochemical sensor for ascorbic acid (AA) was prepared via an one-step electrochemical approach by reducing graphene oxide (rGO) and co-polymerizing neutral red (NR) and rGO to form a pNR/rGO hybrid film on the glassy carbon electrode (pNR/rGO-GCE). Carbon 225-231 trace amine associated receptor 5 Homo sapiens 191-194 28782778-2 2017 The presence of domains of conjugated sp2 carbon, which are formed upon carbonization of precursors at high temperature; nitrogen doping; and as recently shown, the presence of molecular fluorophores, are contributing to the emission of such CDs. Carbon 42-48 Sp2 transcription factor Homo sapiens 38-41 28798314-0 2017 Oxidative coupling of sp 2 and sp 3 carbon-hydrogen bonds to construct dihydrobenzofurans. Carbon 36-42 Sp3 transcription factor Homo sapiens 31-35 28798314-9 2017 Here, the authors report an oxidative coupling between sp 2 and sp 3 carbons by sequentially activating the more active aryl site followed by the alkyl position. Carbon 69-76 Sp2 transcription factor Homo sapiens 55-59 28798314-9 2017 Here, the authors report an oxidative coupling between sp 2 and sp 3 carbons by sequentially activating the more active aryl site followed by the alkyl position. Carbon 69-76 Sp3 transcription factor Homo sapiens 64-68 28485066-2 2017 The reaction proceeds through an oxidative C-N bond formation, followed by an intramolecular C(sp2 )-H bond functionalization/C-O cyclization in one pot. Carbon 43-44 Sp2 transcription factor Homo sapiens 93-98 29964927-9 2017 The content of autochthonous organic carbon in the TOC ranged from 1.02 to 5.14 mg L-1, with an average of 2.54 mg L-1. Carbon 37-43 immunoglobulin kappa variable 1-16 Homo sapiens 83-86 29964927-9 2017 The content of autochthonous organic carbon in the TOC ranged from 1.02 to 5.14 mg L-1, with an average of 2.54 mg L-1. Carbon 37-43 immunoglobulin kappa variable 1-16 Homo sapiens 115-118 29964927-12 2017 The main source of POC was allochthonous organic carbon, and the content of autochthonous organic carbon in the POC ranged from 0.01 to 0.16 mg L-1, with an average of 0.05 mg L-1. Carbon 98-104 immunoglobulin kappa variable 1-16 Homo sapiens 144-147 29964927-12 2017 The main source of POC was allochthonous organic carbon, and the content of autochthonous organic carbon in the POC ranged from 0.01 to 0.16 mg L-1, with an average of 0.05 mg L-1. Carbon 98-104 immunoglobulin kappa variable 1-16 Homo sapiens 176-179 29964927-16 2017 The content of autochthonous organic carbon of the DOC ranged from 0.97 to 5.10 mg L-1, with an average of 2.48 mg L-1. Carbon 37-43 immunoglobulin kappa variable 1-16 Homo sapiens 83-86 29964927-16 2017 The content of autochthonous organic carbon of the DOC ranged from 0.97 to 5.10 mg L-1, with an average of 2.48 mg L-1. Carbon 37-43 immunoglobulin kappa variable 1-16 Homo sapiens 115-118 29964950-3 2017 The results showed that the start-up of shortcut nitrification was successfully achieved in the CSTR and MBR after 44 and 56 days of operation, respectively, with influent C/N=1, temperature around 30C+-1C, pH of 7.5-8.0, and dissolved oxygen (DO) of 0.6-1.0 mg L-1, as well as combining anoxic/aerobic ratio 1:3 (15 min:45 min) with shortened hydraulic retention time (HRT). Carbon 96-97 immunoglobulin kappa variable 1-16 Homo sapiens 262-265 28627043-2 2017 This study shows how a self-rolling process initiated by polymerization of a micropatterned layer of fibronectin (FN) results in the production of carbon nanomaterial-based microtubular fibers. Carbon 147-153 fibronectin 1 Homo sapiens 101-112 28726961-0 2017 Functional single-walled carbon nanotubes "CAR" for targeting dopamine delivery into the brain of parkinsonian mice. Carbon 25-31 nuclear receptor subfamily 1, group I, member 3 Mus musculus 43-46 28726961-2 2017 Herein, we explore the feasibility and efficacy of functional single-walled carbon nanotubes "CAR" (SWCNT-PEGs-Lf) which carry and target-deliver dopamine (DA) to the brain in PD mice for treatment. Carbon 76-82 nuclear receptor subfamily 1, group I, member 3 Mus musculus 94-97 28627043-2 2017 This study shows how a self-rolling process initiated by polymerization of a micropatterned layer of fibronectin (FN) results in the production of carbon nanomaterial-based microtubular fibers. Carbon 147-153 fibronectin 1 Homo sapiens 114-116 28627043-3 2017 The process begins with deposition of carbon nanotube (CNT) or graphene oxide (GO) particles on the FN layer. Carbon 38-44 fibronectin 1 Homo sapiens 100-102 28627043-4 2017 Before polymerization, particles are discrete and nonconducting, but after polymerization the carbon materials become entangled to form an interconnected conducting network clad by FN. Carbon 94-100 fibronectin 1 Homo sapiens 181-183 28471075-1 2017 Herein we report synthesis, structure and properties of a new type of twisted nanographene, which contains an [8]circulene moiety in a polycyclic framework of 96 sp2 carbon atoms. Carbon 166-172 Sp2 transcription factor Homo sapiens 162-165 31457701-7 2017 Two distinct plastic deformation patterns in overstretched pentagraphene are uncovered, depending on the tension directions: one is dominated by structural transition from sp3-carbon-contained penta-(C5) to mixed sp2-carbon polygons and the other is mainly controlled by a stepwise pentagon-to-hexagon transition. Carbon 176-182 Sp3 transcription factor Homo sapiens 172-175 31457701-7 2017 Two distinct plastic deformation patterns in overstretched pentagraphene are uncovered, depending on the tension directions: one is dominated by structural transition from sp3-carbon-contained penta-(C5) to mixed sp2-carbon polygons and the other is mainly controlled by a stepwise pentagon-to-hexagon transition. Carbon 217-223 Sp2 transcription factor Homo sapiens 213-216 28363599-1 2017 A distinctive and personalized nanocarrier is described here for controlled and targeted antitumor drug delivery and real-time bioimaging by combining a redox/enzyme dual-responsive disulfide-conjugated carbon dot with mesoporous silica nanoparticles (MSN-SS-CDHA). Carbon 203-209 moesin Homo sapiens 252-255 28624287-3 2017 Therefore, the ACAA2 enzyme plays an important role in the supply of energy and carbon substrates for lactation and may thus affect milk production traits. Carbon 80-86 3-ketoacyl-CoA thiolase, mitochondrial Ovis aries 15-20 29964615-7 2017 Concentrations of total dissolved n-alkanes(C11-C37) were between 1.756-39.09 mug L-1 with a high carbon number predominance profile without odd-even carbon number preference. Carbon 98-104 immunoglobulin kappa variable 1-16 Homo sapiens 82-85 28577596-1 2017 A simple and accurate immune sensor for quantitative detection of alpha-Fetoprotein (AFP) was developed based on the immobilization of antigen on the surface of Hep-PGA-PPy nanoparticles modified glassy carbon electrodes (GCE). Carbon 203-209 alpha fetoprotein Homo sapiens 66-83 28577596-1 2017 A simple and accurate immune sensor for quantitative detection of alpha-Fetoprotein (AFP) was developed based on the immobilization of antigen on the surface of Hep-PGA-PPy nanoparticles modified glassy carbon electrodes (GCE). Carbon 203-209 alpha fetoprotein Homo sapiens 85-88 28609611-12 2017 The addition of PPh3 promotes the reaction rate and yield of the carbon-carbon bond activation product. Carbon 65-71 caveolin 1 Homo sapiens 16-20 28609611-12 2017 The addition of PPh3 promotes the reaction rate and yield of the carbon-carbon bond activation product. Carbon 72-78 caveolin 1 Homo sapiens 16-20 28617574-0 2017 Synergistic Suppression of Tumor Angiogenesis by the Co-delivering of Vascular Endothelial Growth Factor Targeted siRNA and Candesartan Mediated by Functionalized Carbon Nanovectors. Carbon 163-169 vascular endothelial growth factor A Homo sapiens 70-104 28724997-0 2017 Nitrogen-doped Carbon Dots Mediated Fluorescent on-off Assay for Rapid and Highly Sensitive Pyrophosphate and Alkaline Phosphatase Detection. Carbon 15-21 alkaline phosphatase, placental Homo sapiens 110-130 28736527-4 2017 We found that expression of human COQ9 rescues the growth of the temperature-sensitive yeast mutant, coq9-ts19, on a non-fermentable carbon source and increases the content of Q6, by enhancing Q biosynthesis from 4-hydroxybenzoic acid (4HB). Carbon 133-139 ubiquinone biosynthesis protein COQ9 Saccharomyces cerevisiae S288C 101-105 28598618-2 2017 This new methodology involves tandem (Ar)O-C(sp3) bond cleavage and C(sp2)/C(sp3)-SO2 formation toward divergent synthesis of sulfonyl- and phosphinyl-bifunctionalized 1,3-butadienes or allenes, depending on the substitution at the terminal carbon atoms of allenylphosphine oxides. Carbon 241-247 Sp2 transcription factor Homo sapiens 68-73 28342358-1 2017 Highly efficient simultaneous removal of Pb(II) and p-nitrophenol (PNP) contamination from water was accomplished by nitrogen-functionalized magnetic ordered mesoporous carbon (N-Fe/OMC). Carbon 169-175 submaxillary gland androgen regulated protein 3B Homo sapiens 41-47 28644506-3 2017 Herein, a reduced graphene oxide coated porous carbon nanofiber flexible paper (rGO@S-PCNP) was fabricated and directly used as an additive-free cathode for Li-S batteries. Carbon 47-53 PEST proteolytic signal containing nuclear protein Homo sapiens 86-90 28334792-1 2017 Vitamin B12 is an important cofactor in one-carbon metabolism whose dysregulation is associated with various clinical conditions. Carbon 44-50 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 8-11 28198581-4 2017 In addition, the visualization of a radicalic orbital distribution on an sp2 -hydridized carbon atom is demonstrated. Carbon 89-95 Sp2 transcription factor Homo sapiens 73-76 28560622-4 2017 The performance of MRAHD was better than that of MEC-based autotrophic denitrification for the wastewater treatment with low carbon nitrogen (COD/N) ratio. Carbon 125-131 C-C motif chemokine ligand 28 Homo sapiens 49-52 28717252-5 2017 Direct releases of CO2 from litter layer only accounted for ~19% increases in soil CO2 flux, suggesting that the leaching of dissolved organic carbon (DOC) from litter layer to the topsoil is the major cause of rain-induced soil CO2 pulse. Carbon 143-149 Ras interacting protein 1 Homo sapiens 211-215 28612314-6 2017 The nanocatalysts were much less effective in oxidising metaldehyde than PAC with the same metaldehyde concentration and 0.2 g L-1 loading concentration of materials under UV light; the maximum removal achieved by carbon-doped titanium dioxide (C-1.5) nanocatalyst was around 15% for a 7.5 ppm metaldehyde solution. Carbon 214-220 immunoglobulin kappa variable 1-16 Homo sapiens 127-130 28671531-4 2017 The presence or absence of genes related to carbon catabolism and antibiotic resistance were in agreement with the phenotypic characterization of ACE. Carbon 44-50 angiotensin I converting enzyme Homo sapiens 146-149 28120533-2 2017 We have recently demonstrated that nanovectorization of TRAIL with single-walled carbon nanotubes enhanced TRAIL affinity to DR5. Carbon 81-87 TNF superfamily member 10 Homo sapiens 56-61 28120533-2 2017 We have recently demonstrated that nanovectorization of TRAIL with single-walled carbon nanotubes enhanced TRAIL affinity to DR5. Carbon 81-87 TNF superfamily member 10 Homo sapiens 107-112 28671531-6 2017 However, ACE did not use aromatic compounds and was unable to grow on common carbon sources, such as glucose, xylose, glycerol or citrate. Carbon 77-83 angiotensin I converting enzyme Homo sapiens 9-12 28476770-11 2017 Additionally, both the PhaP phasin and the well-known chaperone GroEL were used to increase the biosynthesis of the biotechnologically relevant compounds ethanol and 1,3-propanediol in recombinant E. coli These findings open the road for the use of these proteins for the manipulation of bacterial strains to optimize the synthesis of diverse bioproducts from renewable carbon sources. Carbon 370-376 GroEL Escherichia coli 64-69 28504418-4 2017 The carbonization of the polymer blend gives turbostratic carbon domains of randomly stacked together sp2 hybridized carbon sheets as well as sp3 hybridized amorphous carbon. Carbon 4-10 Sp2 transcription factor Homo sapiens 102-105 28736501-6 2017 Iodine radionuclides are generally retained in vivo on sp2 carbon atoms in iodoarenes and iodovinyl moieties, but not in iodinated heterocycles or on sp3 carbon atoms. Carbon 59-65 Sp2 transcription factor Homo sapiens 55-58 28504418-4 2017 The carbonization of the polymer blend gives turbostratic carbon domains of randomly stacked together sp2 hybridized carbon sheets as well as sp3 hybridized amorphous carbon. Carbon 4-10 Sp3 transcription factor Homo sapiens 142-145 28504418-4 2017 The carbonization of the polymer blend gives turbostratic carbon domains of randomly stacked together sp2 hybridized carbon sheets as well as sp3 hybridized amorphous carbon. Carbon 58-64 Sp2 transcription factor Homo sapiens 102-105 28504418-4 2017 The carbonization of the polymer blend gives turbostratic carbon domains of randomly stacked together sp2 hybridized carbon sheets as well as sp3 hybridized amorphous carbon. Carbon 58-64 Sp2 transcription factor Homo sapiens 102-105 28644384-4 2017 Carbon signals that resonated at deltaC 126 ppm in the solid state NMR spectra confirmed that sp2 hybridised carbons were present in high concentration in two of the nanoparticle types (AMNP1 and AMNP2). Carbon 0-6 Sp2 transcription factor Homo sapiens 94-97 28644384-4 2017 Carbon signals that resonated at deltaC 126 ppm in the solid state NMR spectra confirmed that sp2 hybridised carbons were present in high concentration in two of the nanoparticle types (AMNP1 and AMNP2). Carbon 109-116 Sp2 transcription factor Homo sapiens 94-97 28295951-0 2017 C 1s Peak of Adventitious Carbon Aligns to the Vacuum Level: Dire Consequences for Material"s Bonding Assignment by Photoelectron Spectroscopy. Carbon 26-32 complement C1s Homo sapiens 0-4 28516178-1 2017 We report the fabrication of a flexible, lightweight and disposable multi walled carbon nanotube (MWCNT)-zinc oxide (ZnO) nanofiber based chemiresistive biosensor for label free detection of the malaria biomarker, histidine rich protein II (HRP2). Carbon 81-87 HDGF like 2 Homo sapiens 241-245 28295951-1 2017 The C 1s signal from ubiquitous carbon contamination on samples forming during air exposure, so called adventitious carbon (AdC) layers, is the most common binding energy (BE) reference in X-ray photoelectron spectroscopy studies. Carbon 32-38 complement C1s Homo sapiens 4-8 28520391-2 2017 A thin layer opto-electrochemical cell is designed, facilitating the visualization of a carbon fiber (diameter 7.0 mum) electrochemical interface. Carbon 88-94 latexin Homo sapiens 115-118 28295951-1 2017 The C 1s signal from ubiquitous carbon contamination on samples forming during air exposure, so called adventitious carbon (AdC) layers, is the most common binding energy (BE) reference in X-ray photoelectron spectroscopy studies. Carbon 116-122 complement C1s Homo sapiens 4-8 28619018-8 2017 Preliminary results show that human growth hormone 1 was also efficiently produced in fermentations of W3110 strain and when glucose was replaced with glycerol as the carbon source. Carbon 167-173 growth hormone 1 Homo sapiens 36-52 28623948-15 2017 Plasma one-carbon metabolites were able to diagnose subjects with a positive CSF profile of AD pathology in APOE epsilon4 carriers. Carbon 11-17 apolipoprotein E Homo sapiens 108-112 27839738-2 2017 The new signal-amplified strategy for sensitive detection of HIgG was based on the catalytic oxidation of ALP-generated products, ascorbic acid (AA), using carbon-based Ag-Au bimetallic as the catalyst and signal enhancer. Carbon 156-162 alkaline phosphatase, placental Homo sapiens 106-109 28535041-6 2017 The crystal structure of a tyrosine kinase Src bound to alpha,beta-CHX-ADP establishes the absolute configuration of the CHX carbon and helps clarify the origin of the remarkable diastereospecificity observed. Carbon 125-131 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 43-46 28327452-1 2017 A novel electrochemical sensor was presented for the determination of L-5-hydroxytryptophan (L-5-HTP) based on a graphene-chitosan molecularly imprinted film modified on the surface of glassy carbon electrode (GR-MIP/GCE). Carbon 192-198 ribosomal protein L5 Homo sapiens 70-73 28461100-1 2017 Graphene is an allotrope of carbon which consists of single layered sp2 hybridized carbon arranged in honey comb lattice. Carbon 28-34 Sp2 transcription factor Homo sapiens 68-71 28537399-1 2017 Palladium-catalyzed arene C(sp2)-H acetoxylation has emerged as a powerful tool to construct a carbon-oxygen (C-O) bond. Carbon 95-101 Sp2 transcription factor Homo sapiens 26-31 28621387-0 2017 Synthesis of MnO2 on Activated Carbon and its Potential Application in the Adsorption of As(V) and Pb(II) in Aqueous Solutions. Carbon 31-37 submaxillary gland androgen regulated protein 3B Homo sapiens 99-105 28611456-1 2017 Carbon fiber papers supported Ag catalysts (Ag/CFP) with different coverage of electro-active site are prepared by electrochemical deposition and used as binder free cathodes in primary aluminum-air (Al-air) battery. Carbon 0-6 complement factor properdin Homo sapiens 47-50 28630918-1 2017 Carbon"s unique ability to have both sp2 and sp3 bonding states gives rise to a range of physical attributes, including excellent mechanical and electrical properties. Carbon 0-6 Sp2 transcription factor Homo sapiens 37-40 28630918-1 2017 Carbon"s unique ability to have both sp2 and sp3 bonding states gives rise to a range of physical attributes, including excellent mechanical and electrical properties. Carbon 0-6 Sp3 transcription factor Homo sapiens 45-48 28630918-2 2017 We show that a series of lightweight, ultrastrong, hard, elastic, and conductive carbons are recovered after compressing sp2-hybridized glassy carbon at various temperatures. Carbon 81-88 Sp2 transcription factor Homo sapiens 121-124 28630918-2 2017 We show that a series of lightweight, ultrastrong, hard, elastic, and conductive carbons are recovered after compressing sp2-hybridized glassy carbon at various temperatures. Carbon 81-87 Sp2 transcription factor Homo sapiens 121-124 28327452-1 2017 A novel electrochemical sensor was presented for the determination of L-5-hydroxytryptophan (L-5-HTP) based on a graphene-chitosan molecularly imprinted film modified on the surface of glassy carbon electrode (GR-MIP/GCE). Carbon 192-198 ribosomal protein L5 Homo sapiens 93-100 28489371-1 2017 Under the conditions of nickel(0) catalysis, enantiomerically enriched vinyl dioxanones engage boroxines or B2(pin)2 in stereospecific cross-coupling to form diverse tetrasubstituted cyclopropanes bearing all-carbon quaternary stereocenters. Carbon 209-215 telomeric repeat binding factor 1 Homo sapiens 108-116 28351765-9 2017 The C10 and C14 homologs were the dominant CP carbon-chain-length groups, contributing 51% and 82% of the total SCCP and MCCP concentrations, respectively. Carbon 46-52 homeobox C10 Homo sapiens 4-7 28505361-1 2017 CO2-concentrating mechanisms (CCMs), based either on active transport of inorganic carbon (biophysical CCMs) or on biochemistry involving supplementary carbon fixation into C4 acids (C4 and CAM), play a major role in global primary productivity. Carbon 83-89 calmodulin 3 Homo sapiens 190-193 28505361-1 2017 CO2-concentrating mechanisms (CCMs), based either on active transport of inorganic carbon (biophysical CCMs) or on biochemistry involving supplementary carbon fixation into C4 acids (C4 and CAM), play a major role in global primary productivity. Carbon 152-158 calmodulin 3 Homo sapiens 190-193 28415460-1 2017 This study reports on the electropolymerization of a low toxic and biocompatible polymer with entitle poly arginine-graphene quantum dots (PARG-GQDs) as a novel strategy for surface modification of glassy carbon (GC) surface and preparation a new interface for biomedical application. Carbon 205-211 poly(ADP-ribose) glycohydrolase Homo sapiens 139-143 27990791-5 2017 The carbon adsorbent AST-120 might be useful to delay the progression of not only CKD but also CVD, osteodystrophy, and sarcopenia by adsorbing its precursor, indole, in the intestines, and consequently reducing the serum levels of indoxyl sulfate. Carbon 4-10 solute carrier family 17 member 5 Homo sapiens 21-24 28415539-0 2017 In vitro cytotoxicity evaluation of nano-carbon particles with different sp2/sp3 ratios. Carbon 41-47 Sp2 transcription factor Homo sapiens 73-76 28415539-0 2017 In vitro cytotoxicity evaluation of nano-carbon particles with different sp2/sp3 ratios. Carbon 41-47 Sp3 transcription factor Homo sapiens 77-80 28566698-4 2017 So carbon-exchange of biocrusts (cyanobacteria crusts-AC1/AC2; cyanolichen crust-LC1; chlorolichen crust-LC2; moss crust-MC) utilizing NRW at various temperatures and light-intensities were determined under simulated and insitu mesocosm experiments. Carbon 3-9 adenylate cyclase 2 Homo sapiens 58-61 28471190-5 2017 TREPR provides deeper insights into the structure of carbon cores, where C sp2 domains are embedded within C sp3 scaffolds. Carbon 53-59 regulator of calcineurin 2 Homo sapiens 73-78 28056439-3 2017 Screen-printed carbon sensors coated with electrochemically reduced graphene oxide (ERGO) and a second set of antibodies selectively capture the biomarker-laden Fe3O4@GO particles, which subsequently catalyze hydrogen peroxide reduction to detect PSA and PSMA. Carbon 15-21 folate hydrolase 1 Homo sapiens 255-259 28167426-0 2017 Removal of Pb(II) and methylene blue from aqueous solution by magnetic hydroxyapatite-immobilized oxidized multi-walled carbon nanotubes. Carbon 120-126 submaxillary gland androgen regulated protein 3B Homo sapiens 11-17 28555106-4 2017 The results showed that hepatic CYP2A5 and Nrf2 expression levels were increased in HFD fed mice accompanied with hepatic 18-carbon FA accumulation. Carbon 125-131 nuclear factor, erythroid derived 2, like 2 Mus musculus 43-47 28555106-13 2017 It was concluded that HFD-induced hepatic 18-carbon FA accumulation contributes to the up-regulation of CYP2A5/2A6 via activating Nrf2. Carbon 45-51 nuclear factor, erythroid derived 2, like 2 Mus musculus 130-134 28167426-1 2017 Magnetic hydroxyapatite-immobilized oxidized multi-walled carbon nanotubes (mHAP-oMWCNTs), an excellent adsorbent for Pb(II) and methylene blue (MB) removal, was synthesized in the present work. Carbon 58-64 submaxillary gland androgen regulated protein 3B Homo sapiens 118-124 28440832-0 2017 Nanoemitters and innate immunity: the role of surfactants and bio-coronas in myeloperoxidase-catalyzed oxidation of pristine single-walled carbon nanotubes. Carbon 139-145 myeloperoxidase Homo sapiens 77-92 28411188-6 2017 Simultaneously, RKIP enhances the Poly(I:C)-induced interaction between TGF-beta-activated kinase 1 and MAPK kinase 3 (MKK3), thus promoting MKK3/6 and p38 activation. Carbon 41-42 mitogen-activated protein kinase kinase 3 Mus musculus 104-117 28411188-6 2017 Simultaneously, RKIP enhances the Poly(I:C)-induced interaction between TGF-beta-activated kinase 1 and MAPK kinase 3 (MKK3), thus promoting MKK3/6 and p38 activation. Carbon 41-42 mitogen-activated protein kinase kinase 3 Mus musculus 119-123 28411188-6 2017 Simultaneously, RKIP enhances the Poly(I:C)-induced interaction between TGF-beta-activated kinase 1 and MAPK kinase 3 (MKK3), thus promoting MKK3/6 and p38 activation. Carbon 41-42 mitogen-activated protein kinase kinase 3 Mus musculus 141-145 28084055-3 2017 Dinuclear complex [3]I activates CS2 with formation of complex [5]I featuring the CS2 molecule bound through the carbon atom to the MIC nitrogen atom and one sulfur atom coordinating to the platinum center. Carbon 113-119 chorionic somatomammotropin hormone 2 Homo sapiens 82-85 28415717-5 2017 In the presence of wild-type p53, cells exposed to C-1311 entered senescence. Carbon 51-52 tumor protein p53 Homo sapiens 29-32 28546895-1 2017 The sp2 carbon-based allotropes have been extensively exploited for the realization of gas sensors in the recent years because of their high conductivity and large specific surface area. Carbon 8-14 Sp2 transcription factor Homo sapiens 4-7 28426934-5 2017 Thus, a new type of predominantly sp2-hybridized nanostructured and ultrathin carbon material emerges, which may be useful to encage or stably bind metal in finely dispersed form. Carbon 78-84 Sp2 transcription factor Homo sapiens 34-37 29965094-8 2017 During the early periods of operating the constructed wetland filled with bark, the carbon releasing amount and velocity increased as the influent NO3--N loading increased. Carbon 84-90 NBL1, DAN family BMP antagonist Homo sapiens 147-150 28128526-0 2017 Thrombospondin-1 and microRNA-1 expression in response to multiwalled carbon nanotubes in alveolar epithelial cells. Carbon 70-76 thrombospondin 1 Homo sapiens 0-31 28464614-10 2017 The strong C1s (C-C) signal is achieved from the region of the cell membrane, i.e., high density of phospholipids, while C1s (C-N) and C1s (C-O) signals are obtained from the core of the cell, in good agreement with the presence of cytoplasm and deoxyribonucleic acid containing cell nucleus. Carbon 11-12 complement C1s Homo sapiens 121-124 28464614-10 2017 The strong C1s (C-C) signal is achieved from the region of the cell membrane, i.e., high density of phospholipids, while C1s (C-N) and C1s (C-O) signals are obtained from the core of the cell, in good agreement with the presence of cytoplasm and deoxyribonucleic acid containing cell nucleus. Carbon 11-12 complement C1s Homo sapiens 121-124 27566160-5 2017 Experimental design performed in this study indicated optimum condition for solar photo-Fenton reaction (20 mg L-1 of Fe2+ and 500 mg L-1 of H2O2; pH 2.8), which achieved 96 % removal of dissolved organic carbon (DOC) and 99 % absorbance removal. Carbon 205-211 L1 cell adhesion molecule Homo sapiens 134-145 28128526-2 2017 Previously, we have shown that multiwalled carbon nanotubes (MWCNT) regulate ECM components TGFbeta and its target Col3A1 in alveolar epithelial cells. Carbon 43-49 transforming growth factor beta 1 Homo sapiens 92-99 28508041-11 2017 Overexpression of the antioxidant enzyme superoxide dismutase 1 (SOD1) reduces carbon-centered adducts and protects TDP1-deficient cells from oxidative stress. Carbon 79-85 superoxide dismutase 1, soluble Mus musculus 41-63 28346686-5 2017 Experiments using GAO derivatives indicated that the gallate moiety required the presence of a long carbon chain for BCRP inhibition. Carbon 100-106 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 117-121 27649928-5 2017 Poly (I:C)-MSCs also impaired T-helper type 1/17 (Th1/17) cell expansion and enhanced the suppressive effects of regulatory T cells (Treg) in vitro and in vivo. Carbon 8-9 negative elongation factor complex member C/D, Th1l Mus musculus 50-56 27633574-8 2017 Carbon ions caused larger increase in the quantity of p53 and p21 compared to therapeutic protons. Carbon 0-6 tumor protein p53 Homo sapiens 54-57 28507511-1 2017 ELOngation of Very Long chain fatty acids (ELOVL)-4 is essential for the synthesis of very long chain-fatty acids (fatty acids with chain lengths >= 28 carbons). Carbon 155-162 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 Mus musculus 43-51 28013367-6 2017 Using human mesothelial cells, we first demonstrate that asbestos and carbon nanotubes induced caspase-1 activation and high-mobility group box 1, interleukin 1 beta and interleukin 18 secretion was blocked by Cytochalasin D (Cyto D) an actin polymerization inhibitor. Carbon 70-76 interleukin 1 beta Homo sapiens 147-165 28508041-11 2017 Overexpression of the antioxidant enzyme superoxide dismutase 1 (SOD1) reduces carbon-centered adducts and protects TDP1-deficient cells from oxidative stress. Carbon 79-85 superoxide dismutase 1, soluble Mus musculus 65-69 28332392-2 2017 The procedure, involving the cleavage of the terminal C(sp2)-H bond of the vinyl moiety and the participation of allenes as two-carbon cycloaddition partner, is attractive in terms of assembly efficiency and environmental friendliness. Carbon 128-134 Sp2 transcription factor Homo sapiens 54-59 28380293-3 2017 Here, we have systematically investigated transcriptomic responses of the THP-1 macrophage cell line and lung tissues of mice, after exposure to several carbon nanomaterials (CNMs). Carbon 153-159 GLI family zinc finger 2 Homo sapiens 74-79 28429737-4 2017 In some breast cancer cells, xCT antiporter expression is upregulated through the antioxidant transcription factor Nrf2 and contributes to their requirement for glucose as a carbon source. Carbon 174-180 NFE2 like bZIP transcription factor 2 Homo sapiens 115-119 28238263-1 2017 Carbon-based molecular junctions consisting of aromatic oligomers between conducting sp2 hybridized carbon electrodes exhibit structure-dependent current densities (J) when the molecular layer thickness (d) exceeds ~5 nm. Carbon 0-6 Sp2 transcription factor Homo sapiens 85-88 28238263-1 2017 Carbon-based molecular junctions consisting of aromatic oligomers between conducting sp2 hybridized carbon electrodes exhibit structure-dependent current densities (J) when the molecular layer thickness (d) exceeds ~5 nm. Carbon 100-106 Sp2 transcription factor Homo sapiens 85-88 28487684-1 2017 Sitting at ~5,000 m water depth on the Congo-Angola margin and ~760 km offshore of the West African coast, the recent lobe complex of the Congo deep-sea fan receives large amounts of fluvial sediments (3-5% organic carbon). Carbon 215-221 neutral sphingomyelinase activation associated factor Homo sapiens 153-156 28150905-0 2017 Development of an Efficient G-Quadruplex-Stabilised Thrombin-Binding Aptamer Containing a Three-Carbon Spacer Molecule. Carbon 96-102 coagulation factor II, thrombin Homo sapiens 52-60 28393948-0 2017 Area-selective passivation of sp2 carbon surfaces by supramolecular self-assembly. Carbon 34-40 Sp2 transcription factor Homo sapiens 30-33 28379246-4 2017 After a light-induced sp2 to sp3 change of the hybridization sp2-nanodomains surrounded by sp3 carbon atoms could be created and the electrons can be confined. Carbon 95-101 Sp2 transcription factor Homo sapiens 22-25 28379246-4 2017 After a light-induced sp2 to sp3 change of the hybridization sp2-nanodomains surrounded by sp3 carbon atoms could be created and the electrons can be confined. Carbon 95-101 Sp3 transcription factor Homo sapiens 29-32 28379246-4 2017 After a light-induced sp2 to sp3 change of the hybridization sp2-nanodomains surrounded by sp3 carbon atoms could be created and the electrons can be confined. Carbon 95-101 Sp2 transcription factor Homo sapiens 61-64 28379246-4 2017 After a light-induced sp2 to sp3 change of the hybridization sp2-nanodomains surrounded by sp3 carbon atoms could be created and the electrons can be confined. Carbon 95-101 Sp3 transcription factor Homo sapiens 91-94 28323404-2 2017 The EPD conditions might also be of interest for the reduction of diazonium salts, which upon the release of N2 molecules and generation of radicals, can form covalent bonds with the sp2 hybridized carbon lattice atoms of rGO films. Carbon 198-204 Sp2 transcription factor Homo sapiens 183-186 27914367-0 2017 Single wall carbon nanotube electrode system capable of quantitative detection of CD4+ T cells. Carbon 12-18 CD4 molecule Homo sapiens 82-85 27914367-2 2017 Here, we developed a fully-integrated single wall carbon nanotube (SWCNT)-based immunosensor capable of selective capture and linear quantification of CD4+ T cells with greater dynamic range. Carbon 50-56 CD4 molecule Homo sapiens 151-154 28420169-0 2017 Ultrasensitive Label-Free Sensing of IL-6 Based on PASE Functionalized Carbon Nanotube Micro-Arrays with RNA-Aptamers as Molecular Recognition Elements. Carbon 71-77 interleukin 6 Homo sapiens 37-41 28420169-1 2017 This study demonstrates the rapid and label-free detection of Interleukin-6 (IL-6) using carbon nanotube micro-arrays with aptamer as the molecular recognition element. Carbon 89-95 interleukin 6 Homo sapiens 62-75 28420169-1 2017 This study demonstrates the rapid and label-free detection of Interleukin-6 (IL-6) using carbon nanotube micro-arrays with aptamer as the molecular recognition element. Carbon 89-95 interleukin 6 Homo sapiens 77-81 28401962-3 2017 The results show that tribochemical reactions promoted by the oil lubrication generate strong structural changes in the carbon hybridization of the ta-C hydrogen-free carbon, with initially high sp3 content. Carbon 120-126 Sp3 transcription factor Homo sapiens 195-198 28401962-3 2017 The results show that tribochemical reactions promoted by the oil lubrication generate strong structural changes in the carbon hybridization of the ta-C hydrogen-free carbon, with initially high sp3 content. Carbon 167-173 Sp3 transcription factor Homo sapiens 195-198 28401962-5 2017 The sp2 planar carbon and oxygen-derived species are the hallmark of these mesoscopic surface structures created on top of colliding asperities as a result of the tribochemical reactions induced by the oleic acid lubrication. Carbon 15-21 Sp2 transcription factor Homo sapiens 4-7 28224683-6 2017 The N-doped porous carbon with sub-1 nm micropore facilitates the rapid diffusion of organic electrolyte ions and improves the conductivity of the encapsulated red P. Furthermore, the porous carbon matrix can buffer the volume change of red P during repeat sodiation/desodiation process, keeping the structure intact after long cycle life. Carbon 19-25 SUB1 regulator of transcription Homo sapiens 31-36 28281345-6 2017 The ns-TA and ns-TR3 results also provide some evidence that radical intermediates are generated through a homolytic carbon-halogen bond cleavage via predominantly the singlet excited state pathway in ACN but via mainly the triplet state pathway in the aqueous solutions. Carbon 117-123 nuclear receptor subfamily 4 group A member 1 Homo sapiens 17-20 28067956-5 2017 Analogously, they can effectively modify the charge/spin distribution on the sp2 -conjugated carbon matrix, leading to optimized intermediate chemisorption and facilitated electron transfer. Carbon 93-99 Sp2 transcription factor Homo sapiens 77-80 28248453-1 2017 We report the experimental observation of nonmonotonic changes in the collective hydration of bovine serum albumin (BSA) in the presence of alcohols of varying carbon-chain lengths, that is, ethanol, 2-propanol, and tert-butyl alcohol (TBA), by using terahertz (THz) time domain spectroscopy. Carbon 160-166 albumin Homo sapiens 101-114 28164392-3 2017 N,N-Dimethylmesitylamine also undergoes a C-H activation at the benzylic ortho sp3 -carbon atom with dihydrogen formation upon treatment with Piers" borane [HB(C6 F5 )2 ]. Carbon 84-90 Sp3 transcription factor Homo sapiens 79-82 28224683-6 2017 The N-doped porous carbon with sub-1 nm micropore facilitates the rapid diffusion of organic electrolyte ions and improves the conductivity of the encapsulated red P. Furthermore, the porous carbon matrix can buffer the volume change of red P during repeat sodiation/desodiation process, keeping the structure intact after long cycle life. Carbon 191-197 SUB1 regulator of transcription Homo sapiens 31-36 28211874-3 2017 In Drosophila pink1 and parkin mutants, mitochondrial defects lead to the compensatory upregulation of the mitochondrial one-carbon cycle metabolism genes by an unknown mechanism. Carbon 125-131 parkin Drosophila melanogaster 24-30 28362276-2 2017 Theoretical charge-density calculations have been performed to study the nature and strength associated with the existence of this intermolecular F...O contact, wherein the F atom is attached to an sp3-hybridized C atom in the case of A1 and to an sp2 hybridized carbon in the case of A2. Carbon 213-214 Sp3 transcription factor Homo sapiens 198-201 28362276-2 2017 Theoretical charge-density calculations have been performed to study the nature and strength associated with the existence of this intermolecular F...O contact, wherein the F atom is attached to an sp3-hybridized C atom in the case of A1 and to an sp2 hybridized carbon in the case of A2. Carbon 213-214 Sp2 transcription factor Homo sapiens 248-251 28362276-2 2017 Theoretical charge-density calculations have been performed to study the nature and strength associated with the existence of this intermolecular F...O contact, wherein the F atom is attached to an sp3-hybridized C atom in the case of A1 and to an sp2 hybridized carbon in the case of A2. Carbon 263-269 Sp3 transcription factor Homo sapiens 198-201 28362276-2 2017 Theoretical charge-density calculations have been performed to study the nature and strength associated with the existence of this intermolecular F...O contact, wherein the F atom is attached to an sp3-hybridized C atom in the case of A1 and to an sp2 hybridized carbon in the case of A2. Carbon 263-269 Sp2 transcription factor Homo sapiens 248-251 28211874-8 2017 Conversely, the genetic enhancement of these one-carbon metabolism genes in pink1 or parkin mutants was neuroprotective. Carbon 49-55 parkin Drosophila melanogaster 85-91 28211874-9 2017 We conclude that mitochondrial dysfunction caused by mutations in the Pink1/Parkin pathway engages ATF4-dependent activation of one-carbon metabolism as a protective response. Carbon 132-138 parkin Drosophila melanogaster 76-82 28338686-2 2017 This is particularly true of heterocycles containing a high proportion of sp3-carbon atoms, which confer precise spatial definition upon chemical probes, drug substances, chiral monomers and the like. Carbon 78-84 Sp3 transcription factor Homo sapiens 74-77 28272870-0 2017 Enhanced Thermal Decomposition Properties of CL-20 through Space-Confining in Three-Dimensional Hierarchically Ordered Porous Carbon. Carbon 126-132 epithelial membrane protein 1 Homo sapiens 45-50 28115241-5 2017 The hPXR activity of the PFCs correlates with the carbon chain length and the functional group of the chemicals. Carbon 50-56 nuclear receptor subfamily 1 group I member 2 Homo sapiens 4-8 28263551-6 2017 On the basis of the result, pairing the Cyt c with semiconductor single-wall carbon nanotubes (s-SWCNT) was predicted to have a favorable band alignment and built-in electrical field for exciton dissociation and charge transfer across the s-SWCNT/Cyt c heterojunction interface. Carbon 77-83 cytochrome c, somatic Homo sapiens 40-45 28263551-6 2017 On the basis of the result, pairing the Cyt c with semiconductor single-wall carbon nanotubes (s-SWCNT) was predicted to have a favorable band alignment and built-in electrical field for exciton dissociation and charge transfer across the s-SWCNT/Cyt c heterojunction interface. Carbon 77-83 cytochrome c, somatic Homo sapiens 247-252 28272870-4 2017 Here, 3D hierarchically ordered porous carbon (3D HOPC) is presented as a catalyst for the thermal decomposition of CL-20 via synthesizing a series of nanostructured CL-20/HOPC composites. Carbon 39-45 epithelial membrane protein 1 Homo sapiens 116-121 28272870-4 2017 Here, 3D hierarchically ordered porous carbon (3D HOPC) is presented as a catalyst for the thermal decomposition of CL-20 via synthesizing a series of nanostructured CL-20/HOPC composites. Carbon 39-45 epithelial membrane protein 1 Homo sapiens 166-171 28265077-6 2017 These results demonstrate that MTHFD1 and SHMT1, which are key enzymes providing one-carbon units for dTMP biosynthesis in the form of 5,10-methylenetetrahydrofolate, are direct targets of As2O3-induced proteolytic degradation, providing a mechanism for arsenic in the etiology of cancer and developmental anomalies. Carbon 85-91 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 31-37 28225107-1 2017 Carbon allotropes constituted of sp2-hybridised carbon atoms display a variety of properties that arise from their delocalised pi-conjugated electronic structure. Carbon 0-6 Sp2 transcription factor Homo sapiens 33-36 28225107-1 2017 Carbon allotropes constituted of sp2-hybridised carbon atoms display a variety of properties that arise from their delocalised pi-conjugated electronic structure. Carbon 48-54 Sp2 transcription factor Homo sapiens 33-36 28225107-3 2017 In this Tutorial Review, we analyse and conceptually categorise chiral synthetic molecular fragments of non-planar sp2-carbon allotropes, including hypothetical forms of carbon that have been proposed to exist as stable entities. Carbon 119-125 Sp2 transcription factor Homo sapiens 115-118 28345640-3 2017 In virtually all optical responses, however, an enhancement in peak intensity with increase of sp3 carbon content, and a vanishing of the peak position shift in monolayer compared to few-layer systems, is observed. Carbon 99-105 Sp3 transcription factor Homo sapiens 95-98 28345640-5 2017 Here we demonstrate, using Raman spectroscopy and in situ electrostatic doping techniques, that the intensity is directly modulated by an additional contribution from photoluminescent pi-conjugated domains surrounded by sp3 carbon regions in graphene monolayers. Carbon 224-230 Sp3 transcription factor Homo sapiens 220-223 28327606-3 2017 The pi electrons are only mobile in the graphitic regions of graphite oxide, which are dispersed and surrounded by sp3-hybridized carbon atoms. Carbon 130-136 Sp3 transcription factor Homo sapiens 115-118 28199792-2 2017 To mitigate adverse effects from DBP exposure, granular activated carbon (GAC) adsorption has been considered as one of the best available technologies for removing NOM (DBP precursor) in drinking water treatment. Carbon 66-72 D-box binding PAR bZIP transcription factor Homo sapiens 33-36 28199792-2 2017 To mitigate adverse effects from DBP exposure, granular activated carbon (GAC) adsorption has been considered as one of the best available technologies for removing NOM (DBP precursor) in drinking water treatment. Carbon 66-72 D-box binding PAR bZIP transcription factor Homo sapiens 170-173 27151437-0 2017 A novel sandwiched electrochemiluminescence immunosensor for the detection of carcinoembryonic antigen based on carbon quantum dots and signal amplification. Carbon 112-118 CEA cell adhesion molecule 3 Homo sapiens 78-102 28238725-3 2017 A subset of these iterative PKSs (iPKSs) contains a C-methyltransferase (CMeT) domain that adds one or more S-adenosylmethionine (SAM)-derived methyl groups to the carbon framework. Carbon 164-170 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 73-77 28225621-3 2017 This includes examples containing a bridgehead sp3 quaternary carbon center as well as the cycloisomerization of one substrate to give the corresponding bicyclic adduct in excellent yield at the gram scale. Carbon 62-68 Sp3 transcription factor Homo sapiens 47-50 28143948-4 2017 We further characterized the independent and combined roles of cyclin C and Jhd2p in controlling H3Lys4 3me and transcription in response to fermentable and nonfermentable carbon at multiple loci. Carbon 172-178 histone demethylase Saccharomyces cerevisiae S288C 76-81 30108813-3 2017 The chirality of the carbon bearing the C2 substituent, as well as the position of the hydroxyl (tolerated at C5, but not at C3) has profound influence on the inhibitory activity of both DAGLalpha and ABHD6, as established using biochemical assays and competitive activity-based protein profiling on mouse brain extracts. Carbon 21-27 abhydrolase domain containing 6 Mus musculus 201-206 28157264-1 2017 In this study, we proposed high-performance chemically regenerative redox fuel cells (CRRFCs) using NO3- /NO with a nitrogen-doped carbon-felt electrode and a chemical regeneration reaction of NO to NO3- via O2 . Carbon 131-137 NBL1, DAN family BMP antagonist Homo sapiens 100-103 28135104-3 2017 Here we report the solution using multiwall carbon nanotubes (MCNTs)@MnO2 nanocomposite cathode integrated with N,N"-bis(salicylidene)ethylenediaminocobalt(II) (CoII-salen) in electrolyte for LABs. Carbon 44-50 mitochondrially encoded cytochrome c oxidase II Homo sapiens 161-165 27816594-0 2017 Electrochemical sandwich-type biosensors for alpha-1 antitrypsin with carbon nanotubes and alkaline phosphatase labeled antibody-silver nanoparticles. Carbon 70-76 serpin family A member 1 Homo sapiens 45-64 27935591-8 2017 Overall, these findings suggest that microbial denitrification can consume plant-available NO3- to low levels at multiple time scales, contributing to N-limitation patterns across sites, particularly in moist, carbon-rich soils. Carbon 210-216 NBL1, DAN family BMP antagonist Homo sapiens 91-94 28265456-3 2017 We identified an atypical SEDC patient with a novel missense mutation in the C-propeptide region of COL2A1. Carbon 29-30 collagen type II alpha 1 chain Homo sapiens 100-106 28221390-3 2017 Simple application of these compounds was found to reduce the electrical resistance by as much as 2/3 without causing any unfavorable chemical modification, which could disrupt the highly conductive network of sp2 carbon atoms. Carbon 214-220 Sp2 transcription factor Homo sapiens 210-213 28042968-0 2017 Effects of serum albumin on the degradation and cytotoxicity of single-walled carbon nanotubes. Carbon 78-84 albumin Homo sapiens 11-24 28042968-1 2017 Neutrophil myeloperoxidase (MPO) and peroxynitrite (ONOO-) can oxidatively biodegrade carboxylated single-walled carbon nanotubes (SWCNTs). Carbon 113-119 myeloperoxidase Homo sapiens 11-26 28042968-1 2017 Neutrophil myeloperoxidase (MPO) and peroxynitrite (ONOO-) can oxidatively biodegrade carboxylated single-walled carbon nanotubes (SWCNTs). Carbon 113-119 myeloperoxidase Homo sapiens 28-31 28189064-0 2017 Oral application of carbon nanofibers in rats increases blood concentration of IL6 and IL10 and decreases locomotor activity. Carbon 20-26 interleukin 6 Rattus norvegicus 79-82 28156117-2 2017 The B(dan) moiety was solely installed into the organic frameworks with the regioselective attachment to a terminal carbon of alkenes employed. Carbon 116-122 NBL1, DAN family BMP antagonist Homo sapiens 6-9 28292465-8 2017 RESULTS: LPS and poly(I:C) significantly decreased phosphorylation of IR-beta, IRS-1, Akt, total PI3K-p85alpha protein expression and glucose uptake. Carbon 24-25 AKT serine/threonine kinase 1 Homo sapiens 86-89 28292465-8 2017 RESULTS: LPS and poly(I:C) significantly decreased phosphorylation of IR-beta, IRS-1, Akt, total PI3K-p85alpha protein expression and glucose uptake. Carbon 24-25 phosphoinositide-3-kinase regulatory subunit 1 Homo sapiens 102-110 27802039-6 2017 Anion-binding chemistry is one of the main topics for bipyrrole-based macrocycles with less efficient or deficient cyclo-pi-conjugation, such as those linked with electronically localized aromatic ring(s), with sp3 carbon(s), and with amido or imine connection(s). Carbon 215-221 Sp3 transcription factor Homo sapiens 211-214 31457465-1 2017 Long-range olefin isomerization of 2-alkenylbenzoic acid derivatives going through two to five sp3-carbon atoms to give (E)-alkenes was achieved with palladium(0) nanoparticles. Carbon 99-105 Sp3 transcription factor Homo sapiens 95-98 28169389-2 2017 Compared to the control device with a standard architecture, the current efficiencies of fluorescent green OLEDs can be enhanced by 47.1% and 48.5% by mixing the surface carbon-coated magnetic FePt (0.5 wt%) and CoPt (0.5 wt%) alloy NPs into poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), yielding the maximum values of 5.40 cd A-1 and 5.45 cd A-1, respectively. Carbon 170-176 BCL2 related protein A1 Homo sapiens 350-353 28169389-2 2017 Compared to the control device with a standard architecture, the current efficiencies of fluorescent green OLEDs can be enhanced by 47.1% and 48.5% by mixing the surface carbon-coated magnetic FePt (0.5 wt%) and CoPt (0.5 wt%) alloy NPs into poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), yielding the maximum values of 5.40 cd A-1 and 5.45 cd A-1, respectively. Carbon 170-176 BCL2 related protein A1 Homo sapiens 366-369 28105812-2 2017 C-P bond formation was achieved coupled with C(sp2)-H functionalization. Carbon 0-1 Sp2 transcription factor Homo sapiens 45-50 27927281-6 2017 The IRS with an iron scrap to activated carbon volume ratio of 3:2 resulted in the highest P adsorption capacity (9.34 +- 0.14 g P kg-1), with minimal pH change and strong adaptability to OM accumulation. Carbon 40-46 isoleucyl-tRNA synthetase 1 Homo sapiens 4-7 28112920-2 2017 Recent advances have shown that nickel catalysts are active toward the coupling of sp3-carbon electrophiles and that well-controlled, light-driven coupling systems are possible. Carbon 87-93 Sp3 transcription factor Homo sapiens 83-86 28217750-2 2017 The basis of this new classification resides on the concept of combining hexagonal diamond (sp3 bonded carbon - lonsdaleite) and ring carbon (sp2 bonded carbon - graphene). Carbon 103-109 Sp3 transcription factor Homo sapiens 92-95 28217750-2 2017 The basis of this new classification resides on the concept of combining hexagonal diamond (sp3 bonded carbon - lonsdaleite) and ring carbon (sp2 bonded carbon - graphene). Carbon 134-140 Sp2 transcription factor Homo sapiens 142-145 27864345-4 2017 Similarly, cell treatment with the NR4A1 small-molecule antagonists 1,1-bis(3-indolyl)-1-(p-hydroxy or p-carbomethoxyphenyl)methane (C-DIM) decreased PAX3-FOXO1A. Carbon 133-134 nuclear receptor subfamily 4 group A member 1 Homo sapiens 35-40 27864345-4 2017 Similarly, cell treatment with the NR4A1 small-molecule antagonists 1,1-bis(3-indolyl)-1-(p-hydroxy or p-carbomethoxyphenyl)methane (C-DIM) decreased PAX3-FOXO1A. Carbon 133-134 paired box 3 Homo sapiens 150-154 27864345-4 2017 Similarly, cell treatment with the NR4A1 small-molecule antagonists 1,1-bis(3-indolyl)-1-(p-hydroxy or p-carbomethoxyphenyl)methane (C-DIM) decreased PAX3-FOXO1A. Carbon 133-134 forkhead box O1 Homo sapiens 155-161 27768936-5 2017 The oxidation mechanism of native and denatured CaM, at a glassy carbon electrode, was investigated using differential pulse voltammetry and electrochemical impedance spectroscopy. Carbon 65-71 calmodulin 1 Homo sapiens 48-51 28049591-5 2017 The highest RBA for the ERalpha was observed with the EE2-BODIPY conjugate (7) featuring a linear eight carbon spacer chain. Carbon 104-110 estrogen receptor 1 Homo sapiens 24-31 27978459-0 2017 Le Carbone, a charcoal supplement, modulates DSS-induced acute colitis in mice through activation of AMPKalpha and downregulation of STAT3 and caspase 3 dependent apoptotic pathways. Carbon 3-10 signal transducer and activator of transcription 3 Mus musculus 133-138 28007895-3 2017 HIF-1 also mediates increased flux through the serine synthesis pathway and mitochondrial one-carbon (folate cycle) metabolism to increase mitochondrial antioxidant production (NADPH and glutathione). Carbon 94-100 hypoxia inducible factor 1 subunit alpha Homo sapiens 0-5 27861899-7 2017 The results demonstrated that short-chain sulfatides with 16 carbon non-hydroxylated fatty acids (C16) and 18 carbon non-hydroxylated fatty acids (C18) or 18 carbon hydroxylated fatty acids (C18-OH) existed in restricted regions of the early embryonic spinal cord, where pro-oligodendroblasts initially appear, and co-localized with Olig2-positive pro-oligodendroblasts. Carbon 110-116 Bardet-Biedl syndrome 9 Homo sapiens 147-150 29671476-0 2017 Multiwalled Carbon Nanotubes Inhibit Steroidogenesis by Disrupting Steroidogenic Acute Regulatory Protein Expression and Redox Status. Carbon 12-18 steroidogenic acute regulatory protein Rattus norvegicus 67-105 29671476-3 2017 By using cytotoxicity assays, radioimmunoassay, western blotting and fluorescence quantitative analysis and imaging methods, multiwall carbon nanotubes were found to inhibit the progesterone secretion of preovulatory ovarian granulosa cells by inhibiting the steroidogenic acute regulatory protein expression, and the influence could be restored after the removal of multiwall carbon nanotubes. Carbon 135-141 steroidogenic acute regulatory protein Rattus norvegicus 259-297 27861899-7 2017 The results demonstrated that short-chain sulfatides with 16 carbon non-hydroxylated fatty acids (C16) and 18 carbon non-hydroxylated fatty acids (C18) or 18 carbon hydroxylated fatty acids (C18-OH) existed in restricted regions of the early embryonic spinal cord, where pro-oligodendroblasts initially appear, and co-localized with Olig2-positive pro-oligodendroblasts. Carbon 110-116 Bardet-Biedl syndrome 9 Homo sapiens 191-194 27861899-7 2017 The results demonstrated that short-chain sulfatides with 16 carbon non-hydroxylated fatty acids (C16) and 18 carbon non-hydroxylated fatty acids (C18) or 18 carbon hydroxylated fatty acids (C18-OH) existed in restricted regions of the early embryonic spinal cord, where pro-oligodendroblasts initially appear, and co-localized with Olig2-positive pro-oligodendroblasts. Carbon 110-116 Bardet-Biedl syndrome 9 Homo sapiens 147-150 27861899-7 2017 The results demonstrated that short-chain sulfatides with 16 carbon non-hydroxylated fatty acids (C16) and 18 carbon non-hydroxylated fatty acids (C18) or 18 carbon hydroxylated fatty acids (C18-OH) existed in restricted regions of the early embryonic spinal cord, where pro-oligodendroblasts initially appear, and co-localized with Olig2-positive pro-oligodendroblasts. Carbon 110-116 Bardet-Biedl syndrome 9 Homo sapiens 191-194 28282046-4 2017 The preferred pathway at moderate forces, a bimolecular SN2 attack of OH- at sulfur, competes with unimolecular C-S bond rupture at about 2 nN, and the latter even becomes barrierless at greater applied forces. Carbon 112-113 solute carrier family 38 member 5 Homo sapiens 56-59 27852133-0 2017 TIMP1 promotes multi-walled carbon nanotube-induced lung fibrosis by stimulating fibroblast activation and proliferation. Carbon 28-34 tissue inhibitor of metalloproteinase 1 Mus musculus 0-5 28282048-0 2017 Hydrolytic cleavage of both CS2 carbon-sulfur bonds by multinuclear Pd(II) complexes at room temperature. Carbon 32-38 chorionic somatomammotropin hormone 2 Homo sapiens 28-31 28282048-2 2017 Here we report a series of air-stable dimeric Pd complexes that mediate the facile hydrolytic cleavage of both CS2 carbon-sulfur bonds at 25 C to produce CO2 and trimeric Pd complexes. Carbon 115-121 chorionic somatomammotropin hormone 2 Homo sapiens 111-114 28282048-4 2017 Isotopic labelling confirms that the carbon and oxygen atoms of CO2 originate from CS2 and H2O, respectively, and reaction intermediates were observed by gas-phase and electrospray ionization mass spectrometry, as well as by Fourier transform infrared spectroscopy. Carbon 37-43 chorionic somatomammotropin hormone 2 Homo sapiens 83-86 28061027-0 2017 Insights into the Oxidation Mechanism of sp2-sp3 Hybrid Carbon Materials: Preparation of a Water-Soluble 2D Porous Conductive Network and Detectable Molecule Separation. Carbon 56-62 Sp2 transcription factor Homo sapiens 41-44 28145459-6 2017 The ecosystem was more efficient during the wet season than the dry season, so that it represented a small carbon sink of 0.16 tC ha-1 yr-1 in the dry season and a considerable carbon sink of 1.14 tC ha-1 yr-1 in the wet season. Carbon 107-113 Rho GTPase activating protein 45 Homo sapiens 130-139 28094367-7 2017 The number of spins calculated per one CNP (NSOP) was found to depend on carbon content in ZnO + xC samples. Carbon 73-79 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 39-42 28061027-0 2017 Insights into the Oxidation Mechanism of sp2-sp3 Hybrid Carbon Materials: Preparation of a Water-Soluble 2D Porous Conductive Network and Detectable Molecule Separation. Carbon 56-62 Sp3 transcription factor Homo sapiens 45-48 28061027-1 2017 A thorough investigation of the oxidation mechanism of sp2-sp3 hybrid carbon materials is helpful for the morphological trimming of graphene. Carbon 70-76 Sp2 transcription factor Homo sapiens 55-58 28061027-1 2017 A thorough investigation of the oxidation mechanism of sp2-sp3 hybrid carbon materials is helpful for the morphological trimming of graphene. Carbon 70-76 Sp3 transcription factor Homo sapiens 59-62 28061027-3 2017 We further demonstrated the difference between traditional and free radical oxidation processes in sp2-sp3 hybrid carbon materials. Carbon 114-120 Sp2 transcription factor Homo sapiens 99-102 28061027-3 2017 We further demonstrated the difference between traditional and free radical oxidation processes in sp2-sp3 hybrid carbon materials. Carbon 114-120 Sp3 transcription factor Homo sapiens 103-106 27951489-3 2017 The alteration of carbon chain linking tertiary amine groups and ferulic acid scaffold markedly influenced the inhibition activity against AChE. Carbon 18-24 acetylcholinesterase (Cartwright blood group) Homo sapiens 139-143 28134240-2 2017 Its strength and stability of attachment come at the price of degrading the carbon nanotubes sp2 network and destroying the tubes electronic and optoelectronic features. Carbon 76-82 Sp2 transcription factor Homo sapiens 93-96 27989130-0 2017 Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage. Carbon 167-173 alkylmercury lyase Escherichia coli 119-123 28094353-7 2017 A 3D NHPC-modified glassy carbon electrode exhibits linear ranges from 0.05 to 14.50 muM, 1.0 to 120.0 muM, and 2.0 to 30.0 muM for DA, AA and UA, respectively. Carbon 26-32 latexin Homo sapiens 85-88 28094353-7 2017 A 3D NHPC-modified glassy carbon electrode exhibits linear ranges from 0.05 to 14.50 muM, 1.0 to 120.0 muM, and 2.0 to 30.0 muM for DA, AA and UA, respectively. Carbon 26-32 latexin Homo sapiens 103-106 28094353-7 2017 A 3D NHPC-modified glassy carbon electrode exhibits linear ranges from 0.05 to 14.50 muM, 1.0 to 120.0 muM, and 2.0 to 30.0 muM for DA, AA and UA, respectively. Carbon 26-32 latexin Homo sapiens 103-106 28167950-8 2017 Accordingly, ohp1 and ohp2 mutants were dependent on external organic carbon sources for growth and did not produce seeds. Carbon 70-76 one-helix protein 2 Arabidopsis thaliana 22-26 28109213-2 2017 On Cu(100) and Cu(111) surfaces, an sp2-type network of carbons can be automatically formed with the help of hydrogen under very low carbon coverages. Carbon 56-63 Sp2 transcription factor Homo sapiens 36-39 28109213-2 2017 On Cu(100) and Cu(111) surfaces, an sp2-type network of carbons can be automatically formed with the help of hydrogen under very low carbon coverages. Carbon 56-62 Sp2 transcription factor Homo sapiens 36-39 28045165-3 2017 By applying alternating voltage pulses and electrical forces, the single-walled CNTs in networks were predominantly transformed into other predetermined sp2 carbon structures (multi-walled CNTs and multi-layered graphitic nanoribbons), showing a larger intensity in a coalescence-induced mode of Raman spectra with the increasing channel width. Carbon 157-163 Sp2 transcription factor Homo sapiens 153-156 28045165-5 2017 The sp3 carbon structures at the small channel are controlled, such that they contain up to about 29.4% networks. Carbon 8-14 Sp3 transcription factor Homo sapiens 4-7 28120861-0 2017 Intracellular degradation of functionalized carbon nanotube/iron oxide hybrids is modulated by iron via Nrf2 pathway. Carbon 44-50 NFE2 like bZIP transcription factor 2 Homo sapiens 104-108 28027437-4 2017 In the course of covalently grafting the molecules to graphene, the sp2 conjugation of carbon atoms was broken, and local sp3 bonds were created. Carbon 87-93 Sp2 transcription factor Homo sapiens 68-71 28027437-4 2017 In the course of covalently grafting the molecules to graphene, the sp2 conjugation of carbon atoms was broken, and local sp3 bonds were created. Carbon 87-93 Sp3 transcription factor Homo sapiens 122-125 27989130-1 2017 The organomercurial lyase MerB has the unique ability to cleave carbon-Hg bonds, and structural studies indicate that three residues in the active site (C96, D99, and C159 in E. coli MerB) play important roles in the carbon-Hg bond cleavage. Carbon 64-70 alkylmercury lyase Escherichia coli 26-30 27989130-1 2017 The organomercurial lyase MerB has the unique ability to cleave carbon-Hg bonds, and structural studies indicate that three residues in the active site (C96, D99, and C159 in E. coli MerB) play important roles in the carbon-Hg bond cleavage. Carbon 217-223 alkylmercury lyase Escherichia coli 26-30 27989130-1 2017 The organomercurial lyase MerB has the unique ability to cleave carbon-Hg bonds, and structural studies indicate that three residues in the active site (C96, D99, and C159 in E. coli MerB) play important roles in the carbon-Hg bond cleavage. Carbon 217-223 alkylmercury lyase Escherichia coli 183-187 28115915-8 2017 RESULTS: Administration of low dose poly I:C upregulated the expression of PD-L1, induced neutrophilia and increased keratinocyte-derived chemokine (KC), macrophage inflammatory protein-1beta (MIP-1beta), and IL-6 in BALF. Carbon 43-44 CD274 antigen Mus musculus 75-80 28194986-2 2017 Existing bulk methods, such as absorbance spectroscopy, can quantify sp2 carbon based on spectral bands, but nanotube length distribution, defects, and carbonaceous impurities can complicate quantification of individual particles. Carbon 73-79 Sp2 transcription factor Homo sapiens 69-72 28115915-8 2017 RESULTS: Administration of low dose poly I:C upregulated the expression of PD-L1, induced neutrophilia and increased keratinocyte-derived chemokine (KC), macrophage inflammatory protein-1beta (MIP-1beta), and IL-6 in BALF. Carbon 43-44 interleukin 6 Mus musculus 209-213 28094298-1 2017 A new two-dimensional (2D) carbon crystal, different from graphene, has been prepared from 1,3,5-trihydroxybenzene, consisting of 4-carbon and 6-carbon rings in 1:1 ratio, named 4-6 carbophene by authors, in which all carbon atoms possess sp2 hybrid orbitals with some distortion, forming an extensive conjugated pi-bonding planar structure. Carbon 27-33 Sp2 transcription factor Homo sapiens 239-242 28094298-2 2017 The angles between the three sigma-bonds of the carbon sp2 orbitals are roughly 120 , 90 , and 150 . Carbon 48-54 Sp2 transcription factor Homo sapiens 55-58 27769942-0 2017 Carbon nanotube-composite hydrogels promote intercalated disc assembly in engineered cardiac tissues through beta1-integrin mediated FAK and RhoA pathway. Carbon 0-6 ras homolog family member A Homo sapiens 141-145 27916559-8 2017 The interference of rhinacanthin-C on the ABC drug transporters (P-gp, MRP1 and MRP2) was evaluated by substrate accumulation assay, using fluorescence spectroscopy technique. Carbon 33-34 ATP binding cassette subfamily C member 1 Homo sapiens 71-75 27846374-3 2017 Here we show that carbon-based nanodiamonds (NDs) coated with ubiquitin (Ub) bind to autophagy receptors (SQSTM1 [sequestosome 1], OPTN [optineurin], and CALCOCO2/NDP52 [calcium binding and coiled-coil domain 2]) and are then linked to MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3) for entry into the selective autophagy pathway. Carbon 18-24 optineurin Homo sapiens 131-135 27530073-8 2017 The difference in the mobility and bioavailability of Cr(VI) and As(V) between wastewater sources can be attributed to the difference in their dissolved organic carbon (DOC) content. Carbon 161-167 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 65-70 27530073-9 2017 The DOC provides carbon as an electron donor for the reduction of As(V) and Cr(VI) and also serves as a complexing agent thereby impacting their mobility and bioavailability. Carbon 17-23 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 66-71 27530073-0 2017 Impact of wastewater derived dissolved organic carbon on reduction, mobility, and bioavailability of As(V) and Cr(VI) in contaminated soils. Carbon 47-53 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 101-106 27270434-5 2017 Activity of the MAPK pathway, as well as other factors, such as HIF1alpha, Myc and MITF, are among those that control the balance between non-oxidative and oxidative branches of central carbon metabolism. Carbon 186-192 hypoxia inducible factor 1 subunit alpha Homo sapiens 64-73 27816890-2 2017 To gain a deeper understanding of these aspects, we investigated a series of thrombin inhibitors in which the basicity of the ligand"s group that accepts an H-bond from Gly216 was modulated via bioisosterism; e.g., a C=O acceptor was made electron deficient or rich via bioisosteric replacements of the adjacent moiety. Carbon 217-218 coagulation factor II, thrombin Homo sapiens 77-85 27796453-8 2017 Separation by porous graphitic carbon liquid chromatography at high temperatures in conjunction with tandem mass spectrometry (PGC-LC-MS/MS) was utilized for unequivocal characterization of glycan isomers. Carbon 31-37 progastricsin Homo sapiens 127-130 27939849-8 2017 In order to re-direct carbon away from sterol production and towards the desired heterologous sesquiterpene, a novel protein destabilisation approach was developed for Erg9p. Carbon 22-28 bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase Saccharomyces cerevisiae S288C 168-173 26660877-0 2017 Apoferritin-templated biosynthesis of manganese nanoparticles and investigation of direct electron transfer of MnNPs-HsAFr at modified glassy carbon electrode. Carbon 142-148 ferritin heavy chain Equus caballus 0-11 27956494-4 2017 We previously showed that Sch9p impact on longevity depends on the nitrogen/carbon ratio. Carbon 76-82 serine/threonine protein kinase SCH9 Saccharomyces cerevisiae S288C 26-31 28027722-4 2017 Celastrol significantly inhibited poly(I:C)-induced expression of adhesion molecules, such as ICAM-1/VCAM-1, and chemokines, such as CCL2, CXCL8, and CXCL10, in CRT-MG human astroglioma cells. Carbon 0-1 vascular cell adhesion molecule 1 Homo sapiens 101-107 27885574-1 2017 Previous studies have shown that carboxylated single-walled carbon nanotubes (SWCNTs) could be oxidatively biodegraded by neutrophil myeloperoxidase (MPO) and peroxynitrite (ONOO-). Carbon 60-66 myeloperoxidase Homo sapiens 133-148 27885574-1 2017 Previous studies have shown that carboxylated single-walled carbon nanotubes (SWCNTs) could be oxidatively biodegraded by neutrophil myeloperoxidase (MPO) and peroxynitrite (ONOO-). Carbon 60-66 myeloperoxidase Homo sapiens 150-153 29152447-1 2017 Graphene, 2D atomic-layer of sp2 carbon, has attracted a great deal of interest for use in solar cells, LEDs, electronic skin, touchscreens, energy storage devices, and microelectronics. Carbon 33-39 Sp2 transcription factor Homo sapiens 29-32 27743362-5 2017 These glycopeptides are then separated and detected using an integrated C18-porous graphitized carbon-liquid chromatography (PGC-LC) setup online coupled to a high-resolution electrospray ionization (ESI)-quadrupole time-of-flight (QTOF)-mass spectrometer operated in a combined higher- and lower-energy CID (stepping-energy CID) mode. Carbon 95-101 Bardet-Biedl syndrome 9 Homo sapiens 72-75 27401256-2 2017 It has recently been described that the uncoupling protein UCP2 transports four carbon metabolites including aspartate. Carbon 80-86 uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus 59-63 31275011-5 2017 We previously showed that the plant specific ubiquitin ligase ATL31 regulates the carbon/nitrogen-nutrient response and pathogen resistance in Arabidopsis, and we identified and characterized the basic biochemical function of an ATL31 homologue in tomato plants (Solanum lycopersicum L.). Carbon 82-88 ubiquitin-40S ribosomal protein S27a Solanum lycopersicum 45-54 28144554-6 2016 Both, low- and high-density foams are comprised of predominantly sp2-type carbon. Carbon 74-80 Sp2 transcription factor Homo sapiens 65-68 27838065-3 2016 Our results indicated that the concentrations, size distributions of chemical compositions and sources of PM at the urban canopy were affected by regional transport due to a stable layer approximately 200 m and higher wind speed at 220 m. The concentrations of PM, Cl- and elemental carbon (EC) in fine particles at 10 m were higher than that at 220 m, while the reverse was true for NO3- and SO42-. Carbon 291-293 NBL1, DAN family BMP antagonist Homo sapiens 384-387 28000780-1 2016 Over the history of carbon, it is generally acknowledged that Bernal AB stacking of the sp2 carbon layers is the unique crystalline form of graphite. Carbon 20-26 Sp2 transcription factor Homo sapiens 88-91 28000780-1 2016 Over the history of carbon, it is generally acknowledged that Bernal AB stacking of the sp2 carbon layers is the unique crystalline form of graphite. Carbon 92-98 Sp2 transcription factor Homo sapiens 88-91 28144544-5 2016 The nanocomposite obtained by the pyrolysis of linear PVA demonstrates higher values of the apparent lithium diffusion coefficient, a higher specific capacity and lower values of charge transfer resistance, which can be related to the more uniform carbon coatings and to the significant content of sp2-hybridized carbon detected by XPS and by Raman spectroscopy. Carbon 313-319 Sp2 transcription factor Homo sapiens 298-301 28330312-12 2016 L-Asparaginase production by C7 was higher with glucose as carbon source and asparagine as nitrogen source. Carbon 59-65 asparaginase and isoaspartyl peptidase 1 Homo sapiens 0-14 27543726-2 2016 Our previous studies showed that pyriproxyfen, a member of the terpene family with fewer carbon atoms (C20) than MF59, enhanced active T helper type-1 (Th1)-biased immune responses. Carbon 89-95 negative elongation factor complex member C/D, Th1l Mus musculus 135-155 28193070-4 2016 After magnetic capture of the modified MBs onto screen-printed carbon working electrodes, the amperometric signal using the system hydroquinone/H2O2 was related to the levels of p53-autoantibodies in the sample. Carbon 63-69 tumor protein p53 Homo sapiens 178-181 27376191-0 2016 A sensitive sandwich-type electrochemical aptasensor for thrombin detection based on platinum nanoparticles decorated carbon nanocages as signal labels. Carbon 118-124 coagulation factor II, thrombin Homo sapiens 57-65 27376191-1 2016 In this work, a novel and sensitive sandwich-type electrochemical aptasensor has been developed for thrombin detection based on platinum nanoparticles (Pt NPs) decorated carbon nanocages (CNCs) as signal tags. Carbon 170-176 coagulation factor II, thrombin Homo sapiens 100-108 27872106-1 2016 BACKGROUND: Serine and glycine interconversion and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1)-mediated 1-carbon transfer are the major sources of methyl groups for 1-carbon metabolism. Carbon 113-119 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 51-92 27872106-1 2016 BACKGROUND: Serine and glycine interconversion and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1)-mediated 1-carbon transfer are the major sources of methyl groups for 1-carbon metabolism. Carbon 113-119 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 94-100 27872106-1 2016 BACKGROUND: Serine and glycine interconversion and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1)-mediated 1-carbon transfer are the major sources of methyl groups for 1-carbon metabolism. Carbon 174-180 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 51-92 27872106-1 2016 BACKGROUND: Serine and glycine interconversion and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1)-mediated 1-carbon transfer are the major sources of methyl groups for 1-carbon metabolism. Carbon 174-180 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 94-100 27646453-1 2016 This study builds upon prior work showing that methane (CH4) could be utilized as the sole electron donor and carbon source in a membrane biofilm reactor (MBfR) for complete perchlorate (ClO4-) and nitrate (NO3-) removal. Carbon 110-116 NBL1, DAN family BMP antagonist Homo sapiens 207-210 26830109-3 2016 OBJECTIVE: The objective of this study is to test (13)C-starch digestion before weaning by measuring enrichment of blood (13)C-glucose in maltase-glucoamylase-null and wild-type mice. Carbon 4-5 maltase-glucoamylase Mus musculus 138-158 27900581-0 2016 Molecular dynamics simulations of the orientation properties of cytochrome c on the surface of single-walled carbon nanotubes. Carbon 109-115 cytochrome c, somatic Homo sapiens 64-76 27900581-2 2016 In the present study, different initial orientations of Cytc on the surface of five types of single-walled carbon nanotubes (SWNTs), with different diameters and chirality, were constructed. Carbon 107-113 cytochrome c, somatic Homo sapiens 56-60 27900581-6 2016 This study promises to provide theoretical guidance for the rational design of bio-sensors or bio-fuel cells by using Cytc-decorated carbon nanotube electrodes. Carbon 133-139 cytochrome c, somatic Homo sapiens 118-122 27062449-0 2016 Spectroscopic studies of bovine serum albumin adsorbed onto magnetic-thermosensitive carbon microspheres. Carbon 85-91 albumin Homo sapiens 32-45 27090411-10 2016 The present study shows the importance of accurate sediment and organic carbon simulations to successfully predict riverine PCB transport. Carbon 72-78 pyruvate carboxylase Homo sapiens 124-127 28032325-0 2016 TiO2 Nanotube-Carbon (TNT-C) as Support for Pt-based Catalyst for High Methanol Oxidation Reaction in Direct Methanol Fuel Cell. Carbon 14-20 chromosome 16 open reading frame 82 Homo sapiens 22-25 27496682-4 2016 In the stem wax, compounds with aliphatic chains longer than 31 carbons (derived from C32 precursors) increased in relative abundance in cpc tcl1 etc1 etc3 over gl1. Carbon 64-71 myb domain protein 0 Arabidopsis thaliana 161-164 27858021-4 2016 This provides further evidence that outer-sphere redox processes on metal and sp2 carbon electrodes appear to be adiabatic. Carbon 82-88 Sp2 transcription factor Homo sapiens 78-81 27874114-2 2016 Here we report a conceptually new design principle for creating supracolloidal fullerene-like cages through the self-assembly of soft patchy particles interacting via directional nonbonded interactions by mimicking non-planar sp2 hybridized carbon atoms in C60. Carbon 241-247 Sp2 transcription factor Homo sapiens 226-229 27897198-4 2016 While jhd2 caused only limited gene expression defects in fermenting cells, transcript profiling and physiological measurements show that JHD2 restricts mitochondrial respiratory capacity in cells grown in non-fermentable carbon in an H3K4me-dependent manner. Carbon 223-229 histone demethylase Saccharomyces cerevisiae S288C 139-143 27749055-7 2016 Tests with 29 CASP11 human-prediction targets with length less than 400 amino-acid residues demonstrated that the consensus-fragment approach gave better results, i.e., lower alpha-carbon root-mean-square deviation from the experimental structures, higher template modeling score, and global distance test total score values than the best of the parent server models. Carbon 181-187 SR-related CTD associated factor 11 Homo sapiens 14-20 27897198-5 2016 In association with these phenotypes, we find that JHD2 limits yeast proliferative capacity under physiologically challenging conditions as measured by both replicative lifespan and colony growth on non-fermentable carbon. Carbon 215-221 histone demethylase Saccharomyces cerevisiae S288C 51-55 27685831-4 2016 The obtained water-dispersible H-MON spheres bearing sp- and sp2 -hybridized carbon atoms possess a highly conjugated electronic structure and show low reduction potential; thus, they can serve as a reducing agent and stabilizer for electroless deposition of highly dispersed Pd clusters to form a Pd/H-MON spherical hollow nanocomposite. Carbon 77-83 Sp2 transcription factor Homo sapiens 61-64 27892532-1 2016 First-principles calculations are performed to identify the pristine and Si doped 3D metallic T6 carbon structure (having both sp2 and sp3 type hybridization) as a new carbon based anode material. Carbon 97-103 Sp2 transcription factor Homo sapiens 127-130 27892532-1 2016 First-principles calculations are performed to identify the pristine and Si doped 3D metallic T6 carbon structure (having both sp2 and sp3 type hybridization) as a new carbon based anode material. Carbon 97-103 Sp3 transcription factor Homo sapiens 135-138 27883045-9 2016 Thus, AMCase can function as a protease-resistant major glycosidase under the conditions of stomach and intestine and degrade chitin substrates to produce (GlcNAc)2, a source of carbon, nitrogen and energy. Carbon 178-184 chitinase, acidic 1 Mus musculus 6-12 27920551-6 2016 Yeast expressing Gat1p and Lpt1p had phospholipids enriched with acyl chains that were unsaturated, 18 carbons long, and paired for length. Carbon 103-110 lysophospholipid acyltransferase Saccharomyces cerevisiae S288C 27-32 27797503-3 2016 Pristine sp2-hybridized, hexagonal arranged carbon atoms exhibit a symmetric reactivity. Carbon 44-50 Sp2 transcription factor Homo sapiens 9-12 27875893-1 2016 First-principles molecular dynamics simulations are used to investigate the chemical behavior of bulk thioacetaldehyde (MeC(H)S) in response to changes in pressure, P. The simulations show that these molecules oligomerize in response to applied P. Oligomerization is initiated through C-S bond formation, with constrained dynamics simulations showing that the barrier to this reaction step is lowered significantly by applied P. Subsequent reactions involving the formation of additional C-S bonds or radical processes that lead to S-S and C-C bonds lengthen the oligomers. Carbon 285-286 C-C motif chemokine ligand 28 Homo sapiens 120-123 27875893-1 2016 First-principles molecular dynamics simulations are used to investigate the chemical behavior of bulk thioacetaldehyde (MeC(H)S) in response to changes in pressure, P. The simulations show that these molecules oligomerize in response to applied P. Oligomerization is initiated through C-S bond formation, with constrained dynamics simulations showing that the barrier to this reaction step is lowered significantly by applied P. Subsequent reactions involving the formation of additional C-S bonds or radical processes that lead to S-S and C-C bonds lengthen the oligomers. Carbon 285-286 C-C motif chemokine ligand 28 Homo sapiens 120-123 27799657-3 2016 By developing genetically engineered mouse models and primary pancreatic epithelial cells, and employing transcriptional, proteomics, and metabolic analyses, we find that oncogenic cooperation between LKB1 loss and KRAS activation is fuelled by pronounced mTOR-dependent induction of the serine-glycine-one-carbon pathway coupled to S-adenosylmethionine generation. Carbon 307-313 serine/threonine kinase 11 Mus musculus 201-205 27766842-3 2016 The chelation effect ensures the homodispersion of Fe in the polymer segments of the precursor, so that an effective catalytic conversion from sp3 to sp2 carbon occurs, enabling free rearrangement of graphene sheets into expanded nanographite and carbon micropores. Carbon 154-160 Sp3 transcription factor Homo sapiens 143-146 27806576-1 2016 When two pi-conjugated fragments are connected by a bond between two sp2 carbon atoms, a torsion around this bond is expected to break the overall pi-conjugation. Carbon 73-79 Sp2 transcription factor Homo sapiens 69-72 27766842-3 2016 The chelation effect ensures the homodispersion of Fe in the polymer segments of the precursor, so that an effective catalytic conversion from sp3 to sp2 carbon occurs, enabling free rearrangement of graphene sheets into expanded nanographite and carbon micropores. Carbon 154-160 Sp2 transcription factor Homo sapiens 150-153 27766842-3 2016 The chelation effect ensures the homodispersion of Fe in the polymer segments of the precursor, so that an effective catalytic conversion from sp3 to sp2 carbon occurs, enabling free rearrangement of graphene sheets into expanded nanographite and carbon micropores. Carbon 247-253 Sp3 transcription factor Homo sapiens 143-146 27766842-3 2016 The chelation effect ensures the homodispersion of Fe in the polymer segments of the precursor, so that an effective catalytic conversion from sp3 to sp2 carbon occurs, enabling free rearrangement of graphene sheets into expanded nanographite and carbon micropores. Carbon 247-253 Sp2 transcription factor Homo sapiens 150-153 27581396-0 2016 Conformational control of human transferrin covalently anchored to carbon-coated iron nanoparticles in presence of a magnetic field. Carbon 67-73 transferrin Homo sapiens 32-43 26828117-1 2016 Sedoheptulose 1,7-bisphosphatase (SBPase), a nuclear-encoded chloroplastic enzyme, is an important rate-limiting enzyme of the carbon fixation cycle (Calvin cycle). Carbon 127-133 uncharacterized protein Chlamydomonas reinhardtii 0-32 26828117-1 2016 Sedoheptulose 1,7-bisphosphatase (SBPase), a nuclear-encoded chloroplastic enzyme, is an important rate-limiting enzyme of the carbon fixation cycle (Calvin cycle). Carbon 127-133 uncharacterized protein Chlamydomonas reinhardtii 34-40 27315521-1 2016 A facile strategy was developed to prepare mesoporous structured molecularly imprinted polymers capped carbon dots (M-MIPs@CDs) fluorescence sensor for highly sensitive and selective determination of TNT. Carbon 103-109 chromosome 16 open reading frame 82 Homo sapiens 200-203 27726336-5 2016 A simple and cost-effective ASC construction was demonstrated with ZnO@MnO2 NFs as a battery-type cathode material and a commercial-quality activated carbon as a capacitor-type anode material. Carbon 150-156 PYD and CARD domain containing Homo sapiens 28-31 27709206-0 2016 Iron-catalyzed oxidative sp3 carbon-hydrogen bond functionalization of 3,4-dihydro-1,4-benzoxazin-2-ones. Carbon 29-35 Sp3 transcription factor Homo sapiens 25-28 27709206-1 2016 A novel and efficient iron-catalyzed sp3 carbon-hydrogen bond functionalization of benzoxazinone derivatives has been developed. Carbon 41-47 Sp3 transcription factor Homo sapiens 37-40 27708059-3 2016 We describe C (sp3)-C (sp3) bond-forming reactions on proteins under biocompatible conditions, which exploit unusual carbon free-radical chemistry, and use them to form Cbeta-Cgamma bonds with altered side chains. Carbon 117-123 Sp3 transcription factor Homo sapiens 15-18 27708059-3 2016 We describe C (sp3)-C (sp3) bond-forming reactions on proteins under biocompatible conditions, which exploit unusual carbon free-radical chemistry, and use them to form Cbeta-Cgamma bonds with altered side chains. Carbon 117-123 Sp3 transcription factor Homo sapiens 23-26 27581396-2 2016 Herein, we report that covalent anchoring of human transferrin to carbon-coated iron magnetic nanoparticles functionalized with carboxylic groups (Fe@C-COOH Nps) in the presence of magnetic field results in its conformational integrity and electroactivity. Carbon 150-151 transferrin Homo sapiens 51-62 27581396-7 2016 We showed that it is possible to attach, without changing pH, more than one single layer of transferrin to the Fe@C-COOH Nps. Carbon 114-115 transferrin Homo sapiens 92-103 27934214-6 2016 The reduction of few-layer graphenes introduces strain, allows tuning of optical transmission and fluorescence, and opens synthetic routes to long sought-after films containing sp3-hybridized carbon. Carbon 192-198 Sp3 transcription factor Homo sapiens 177-180 27750195-2 2016 Our working group has recently demonstrated that nanovectorization of TRAIL with single wall carbon nanotubes (abbreviated NPT) enhanced TRAIL affinity to the high affinity site DR5 and increased pro apoptotic potential in different human tumor cell lines. Carbon 93-99 TNF superfamily member 10 Homo sapiens 70-75 27750195-2 2016 Our working group has recently demonstrated that nanovectorization of TRAIL with single wall carbon nanotubes (abbreviated NPT) enhanced TRAIL affinity to the high affinity site DR5 and increased pro apoptotic potential in different human tumor cell lines. Carbon 93-99 TNF superfamily member 10 Homo sapiens 137-142 27417189-4 2016 This review aims to provide an overview of the achievements made in the iodine(iii) mediated fluorinations of aliphatic Csp2-carbon atoms with special focus on the opportunities provided by this exciting class of hypervalent substances. Carbon 125-131 regulator of calcineurin 2 Homo sapiens 120-124 27843311-3 2016 Active carbon nanoparticles (ACNP) were conjugated to the chemotherapeutic agent, doxorubicin (DOX), and the nanoliposome carrier, DSPE-PEG2000 and DSPE-PEG2000-NH2 conjugated to the human anti-CD20 monoclonal antibody that targets B-lymphocytes. Carbon 7-13 keratin 20 Homo sapiens 194-198 27581396-2 2016 Herein, we report that covalent anchoring of human transferrin to carbon-coated iron magnetic nanoparticles functionalized with carboxylic groups (Fe@C-COOH Nps) in the presence of magnetic field results in its conformational integrity and electroactivity. Carbon 66-72 transferrin Homo sapiens 51-62 27614147-0 2016 Binding of human IgG to single-walled carbon nanotubes accelerated myeloperoxidase-mediated degradation in activated neutrophils. Carbon 38-44 myeloperoxidase Homo sapiens 67-82 27377346-3 2016 Studies on isomeric PC sets containing a saturated acyl chain of 6 to 24 carbons in the sn1 or sn2 position in micelles showed an abrupt decrease in hydrolysis when the length of the sn1 or sn2 chain exceeded 17 carbons suggesting that the acyl binding cavity on the enzyme is of the corresponding length. Carbon 73-80 solute carrier family 38 member 3 Homo sapiens 88-91 27377346-3 2016 Studies on isomeric PC sets containing a saturated acyl chain of 6 to 24 carbons in the sn1 or sn2 position in micelles showed an abrupt decrease in hydrolysis when the length of the sn1 or sn2 chain exceeded 17 carbons suggesting that the acyl binding cavity on the enzyme is of the corresponding length. Carbon 212-219 solute carrier family 38 member 3 Homo sapiens 88-91 27476911-11 2016 Relative absorbance contribution per carbon atom was 0.06 (ratio 1.06 for C18 standard, 0.91 for C16 standard). Carbon 37-43 Bardet-Biedl syndrome 9 Homo sapiens 74-77 27778217-7 2016 Significantly, maximum total soil carbon density (90.82 t C ha-1) was observed in 0.4-0.5 NDVI followed by 0.3-0.4 NDVI (77.12 t C ha-1). Carbon 34-40 Rho GTPase activating protein 45 Homo sapiens 60-64 27778217-7 2016 Significantly, maximum total soil carbon density (90.82 t C ha-1) was observed in 0.4-0.5 NDVI followed by 0.3-0.4 NDVI (77.12 t C ha-1). Carbon 34-40 Rho GTPase activating protein 45 Homo sapiens 131-135 27757453-1 2016 We report here for the first time with quantitative details that the combination of pi-pi stacking of pyrenecarboxylic acid with chemically carboxylated multiwalled carbon nanotubes (MWNT-COOH) offers superior sensitivity compared to MWNT-COOH alone for serum insulin measurements and that this combination is broadly applicable for biosensors, drug delivery, and catalytic systems. Carbon 165-171 insulin Homo sapiens 260-267 27730346-0 2016 Stanniocalcin 1 Enhances Carbon Flux from Glucose to Lipids in White Retroperitoneal Adipose Tissue in the Fed Rat. Carbon 25-31 stanniocalcin 1 Rattus norvegicus 0-15 27665739-7 2016 Overexpression of miR-374 sensitized PANC-1 and MIA PaCa-2 cells toward carbon ion beam radiation. Carbon 72-78 MIA SH3 domain containing Homo sapiens 48-51 27545321-4 2016 A theranostics nanoplatform based on luminescent carbon particles decorated with cucurbit[6]uril is introduced for enhancing the solubility of niclosamide, a STAT-3 inhibitor. Carbon 49-55 signal transducer and activator of transcription 3 Homo sapiens 158-164 27647772-0 2016 Crucial Role of P2X7 Receptor in Regulating Exocytosis of Single-Walled Carbon Nanotubes in Macrophages. Carbon 72-78 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 16-29 27481343-2 2016 The adsorption capacity of an activated carbon - calcium alginate composite material (ACAA-Ca) has been tested with the aim of developing a new and more efficient adsorbent material to remove Pb(II) ion from aqueous solution. Carbon 40-46 submaxillary gland androgen regulated protein 3B Homo sapiens 192-198 27639109-1 2016 A method is described for the quantification of the sp2, sp3 and intermediate hybridizations in several carbon (C) material samples. Carbon 104-114 Sp2 transcription factor Homo sapiens 52-55 27791036-5 2016 Examination of the cellular metabolome showed that FLT3 inhibition by itself causes profound alterations in central carbon metabolism, resulting in impaired production of the antioxidant factor glutathione, which was further impaired by ATM or G6PD inactivation. Carbon 116-122 fms related receptor tyrosine kinase 3 Homo sapiens 51-55 26934500-7 2016 As a result, the sp3 diamond structure would be converted to the sp2 carbon structure, which can be easily etched. Carbon 69-75 Sp3 transcription factor Homo sapiens 17-20 26934500-7 2016 As a result, the sp3 diamond structure would be converted to the sp2 carbon structure, which can be easily etched. Carbon 69-75 Sp2 transcription factor Homo sapiens 65-68 27749040-1 2016 Preparation of a range of enantioenriched beta-fluoro amines (alpha,beta-disubstituted) is described in which the nitrogen and fluorine atoms are attached to sp3-hybridized carbons. Carbon 173-180 Sp3 transcription factor Homo sapiens 158-161 27767190-5 2016 BP-2, which contains a two-carbon linker and a trimethyl quaternary ammonium, displayed a fluorescence intensity and quantum yield that were both linearly correlated with solvent polarity. Carbon 27-33 BP2 Homo sapiens 0-4 27384038-2 2016 An electrochemical immunosensor for the determination of the multifunctional Transforming Growth Factor beta1 (TGF-beta1) cytokine has been prepared using multi-walled carbon nanotube (MWCNT)-modified screen-printed carbon electrodes. Carbon 168-174 transforming growth factor beta 1 Homo sapiens 77-109 27384038-2 2016 An electrochemical immunosensor for the determination of the multifunctional Transforming Growth Factor beta1 (TGF-beta1) cytokine has been prepared using multi-walled carbon nanotube (MWCNT)-modified screen-printed carbon electrodes. Carbon 168-174 transforming growth factor beta 1 Homo sapiens 111-120 27384038-2 2016 An electrochemical immunosensor for the determination of the multifunctional Transforming Growth Factor beta1 (TGF-beta1) cytokine has been prepared using multi-walled carbon nanotube (MWCNT)-modified screen-printed carbon electrodes. Carbon 216-222 transforming growth factor beta 1 Homo sapiens 77-109 27384038-2 2016 An electrochemical immunosensor for the determination of the multifunctional Transforming Growth Factor beta1 (TGF-beta1) cytokine has been prepared using multi-walled carbon nanotube (MWCNT)-modified screen-printed carbon electrodes. Carbon 216-222 transforming growth factor beta 1 Homo sapiens 111-120 27764189-6 2016 We found that HSA and other serum albumins bind to 12 carbon acyl side chain of GML at low micromolar affinities and restores the TCR-induced formation of LAT, PLC-gamma1, and AKT microclusters at the plasma membrane. Carbon 54-60 AKT serine/threonine kinase 1 Homo sapiens 176-179 27759024-7 2016 This work demonstrates that real-time imaging under controlled atmosphere is a powerful method for designing synthesis protocols for sp2 carbon nanostructures in between graphene and graphite. Carbon 137-143 Sp2 transcription factor Homo sapiens 133-136 27668688-5 2016 Raman depth imaging successfully detected that the generated carbon in the discolored layer was composed of amorphous carbon and complex sp/sp2-carbon compounds containing C C or conjugated C C/C C structures. Carbon 61-67 Sp2 transcription factor Homo sapiens 140-143 27544824-5 2016 Carbon fibre amperometry showed that SERT modulated the ability of 5-HT1A receptors to inhibit exocytosis. Carbon 0-6 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 Mus musculus 37-41 27544824-5 2016 Carbon fibre amperometry showed that SERT modulated the ability of 5-HT1A receptors to inhibit exocytosis. Carbon 0-6 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 67-73 27709822-0 2016 Use of a Catalytic Chiral Leaving Group for Asymmetric Substitutions at sp3 -Hybridized Carbon Atoms: Kinetic Resolution of beta-Amino Alcohols by p-Methoxybenzylation. Carbon 88-94 Sp3 transcription factor Homo sapiens 72-75 27704079-2 2016 Two model redox analytes were used to evaluate the electrode response because of their positive detection potentials and propensity (i.e., reaction products) to adsorb and foul sp2 carbon electrodes: tyrosine and tryptophan. Carbon 181-187 Sp2 transcription factor Homo sapiens 177-180 27741250-7 2016 Further analyses revealed that interacting mutations in HOG1 and ISU1 unexpectedly elevated mitochondrial respiratory proteins and enabled rapid aerobic respiration of xylose and other non-fermentable carbon substrates. Carbon 201-207 mitogen-activated protein kinase HOG1 Saccharomyces cerevisiae S288C 56-60 27709822-1 2016 A catalytic strategy was developed for asymmetric substitution reactions at sp3 -hybridized carbon atoms by using a chiral alkylating agent generated in situ from trichloroacetimidate and a chiral phosphoric acid. Carbon 92-98 Sp3 transcription factor Homo sapiens 76-79 27617624-1 2016 A chemo- and regioselective intermolecular sp3 C-H and sp2 C-H coupling reaction for C-C bond formation is described to access unsymmetrical diaryl acetamides under TM-free conditions from sec- and tert-arylacetamides and nitroarenes using tert-butoxide base in DMSO at room temperature. Carbon 47-48 Sp3 transcription factor Homo sapiens 43-46 27569910-3 2016 Graphene, a monolayer material composed of sp2-hybridized carbon atoms hexagonally arranged in a two-dimensional structure, can be easily functionalized by chemical modification. Carbon 58-64 Sp2 transcription factor Homo sapiens 43-46 27877907-2 2016 This structure is obtained by adding hydrogen atoms to the sp2 bonded carbon atoms of penta-graphene. Carbon 70-76 Sp2 transcription factor Homo sapiens 59-62 27233212-1 2016 Nano-graphene as a class of two-dimensional sp2 carbon nanomaterial has attracted tremendous attentions in various fields in the past decade. Carbon 48-54 Sp2 transcription factor Homo sapiens 44-47 27598034-10 2016 Molecular docking analysis suggests that 15d-PGJ2 preferentially binds to PHD2 in the vicinity of the Cys201 residue based on binding energies and carbon-sulfur distances. Carbon 147-153 egl-9 family hypoxia inducible factor 1 Homo sapiens 74-78 27628060-1 2016 A novel screen-printed microfluidic paper-based analytical device with all-carbon electrode-enabled electrochemical assay (SP-ACE-EC-muPAD) has been developed. Carbon 75-81 angiotensin I converting enzyme Homo sapiens 126-129 27469000-5 2016 Metabolite profiling identified the cyclopropane ring-opened metabolites from representative irreversible inhibitors, suggesting irreversible binding of the carbon-centered radical species with CYP3A4. Carbon 157-163 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 194-200 27469000-8 2016 The docking study with CYP3A4 suggested that a methyl moiety introduced at the carbon atom at the root of the primary amine disrupts formation of the MI complex between the heme and the nitroso intermediate because of steric hindrance. Carbon 79-85 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 23-29 27406851-6 2016 In addition to growth by fermentation and nitrate reduction, this strain was able to reduce Fe(III), Mn(IV), Co(III) and Cr(VI) when H2 or organic carbon was available as the electron donor, but did not actively reduce oxidized sulfur compounds (e.g. sulfate, thiosulfate or S0). Carbon 147-153 mitochondrially encoded cytochrome c oxidase III Homo sapiens 95-98 27520072-0 2016 Immunization with functionalized carbon nanotubes enhances the antibody response against mode antigen ovalbumin. Carbon 33-39 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 102-111 27520072-2 2016 We have covalently conjugated the mode antigen ovalbumin (OVA) to functionalized multi-walled carbon nanotubes. Carbon 94-100 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 47-56 27406851-6 2016 In addition to growth by fermentation and nitrate reduction, this strain was able to reduce Fe(III), Mn(IV), Co(III) and Cr(VI) when H2 or organic carbon was available as the electron donor, but did not actively reduce oxidized sulfur compounds (e.g. sulfate, thiosulfate or S0). Carbon 147-153 mitochondrially encoded cytochrome c oxidase III Homo sapiens 109-116 27519409-9 2016 Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris. Carbon 177-183 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 0-5 27287127-0 2016 Effects of transferrin conjugated multi-walled carbon nanotubes in lung cancer delivery. Carbon 47-53 transferrin Homo sapiens 11-22 27287127-1 2016 The aim of this study was to develop multi-walled carbon nanotubes (MWCNT) which were covalently conjugated with transferrin by carbodiimide chemistry and loaded with docetaxel as a model drug for effective treatment of lung cancer in comparison with the commercial docetaxel injection (Docel ). Carbon 50-56 transferrin Homo sapiens 113-124 27337244-7 2016 The levels of 29-carbon long alkanes, ketones, and secondary alcohols, which are the most abundant components of stem waxes, were significantly reduced in wri4 stems relative to the wild type. Carbon 17-23 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 155-159 27335160-4 2016 To improve the soluble yield, expression of TRAIL in Escherichia coli was induced with low IPTG concentration (0.1 mM) at low temperature (28 C) supplemented with ZnSO4 (0.5 mM), using glycerol as carbon source. Carbon 198-204 TNF superfamily member 10 Homo sapiens 44-49 27519409-0 2016 Methanol Expression Regulator 1 (Mxr1p) Is Essential for the Utilization of Amino Acids as the Sole Source of Carbon by the Methylotrophic Yeast, Pichia pastoris. Carbon 110-116 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 33-38 27519409-4 2016 Mxr1p regulates the expression of several genes involved in the utilization of amino acids as the sole source of carbon and nitrogen. Carbon 113-119 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 0-5 27745672-0 2016 Influence of carbon sources on nutrient removal in A2/O-MBRs: Availability assessment of internal carbon source. Carbon 98-104 ATPase H+ transporting V0 subunit a2 Homo sapiens 51-60 27745672-1 2016 Both internal carbon source and some external carbon sources were used to improve the nutrient removal in Anaerobic-Anoxic-Oxic-Membrane Bioreactor (A2/O-MBRs), and their technical and cost analysis was investigated. Carbon 14-20 ATPase H+ transporting V0 subunit a2 Homo sapiens 149-158 27745672-1 2016 Both internal carbon source and some external carbon sources were used to improve the nutrient removal in Anaerobic-Anoxic-Oxic-Membrane Bioreactor (A2/O-MBRs), and their technical and cost analysis was investigated. Carbon 46-52 ATPase H+ transporting V0 subunit a2 Homo sapiens 149-158 27519409-9 2016 Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris. Carbon 177-183 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 15-20 27519409-9 2016 Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris. Carbon 177-183 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 15-20 27571509-0 2016 Isotope-Labeling Studies Support the Electrophilic Compound I Iron Active Species, FeO(3+), for the Carbon-Carbon Bond Cleavage Reaction of the Cholesterol Side-Chain Cleavage Enzyme, Cytochrome P450 11A1. Carbon 100-106 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 184-204 27714111-0 2016 Transferrin conjugated nontoxic carbon dots for doxorubicin delivery to target pediatric brain tumor cells. Carbon 32-38 transferrin Homo sapiens 0-11 27714111-7 2016 In this study, carbon dots-transferrin-doxorubicin covalent conjugate (C-Dots-Trans-Dox) was synthesized, characterized by different spectroscopic techniques and investigated for the potential application as a drug delivery system for anticancer drug doxorubicin to treat pediatric brain tumors. Carbon 15-21 transferrin Homo sapiens 27-38 27524608-4 2016 Only thiosemicarbazones with electron-withdrawing substituents at the imine carbon mediated Pgp-dependent potentiated cytotoxicity, which was reversed by Pgp inhibition. Carbon 76-82 ATP binding cassette subfamily B member 1 Homo sapiens 92-95 27524608-4 2016 Only thiosemicarbazones with electron-withdrawing substituents at the imine carbon mediated Pgp-dependent potentiated cytotoxicity, which was reversed by Pgp inhibition. Carbon 76-82 ATP binding cassette subfamily B member 1 Homo sapiens 154-157 27659937-4 2016 Our previous studies showed that PARP-1 depletion makes the cells more radiosensitive towards carbon ion than gamma. Carbon 94-100 poly(ADP-ribose) polymerase 1 Homo sapiens 33-39 27659937-17 2016 These data open up the possibilities of improvement of carbon ion therapy with PARP-1 inhibition to control highly metastatic cancers. Carbon 55-61 poly(ADP-ribose) polymerase 1 Homo sapiens 79-85 27571509-1 2016 The enzyme cytochrome P450 11A1 cleaves the C20-C22 carbon-carbon bond of cholesterol to form pregnenolone, the first 21-carbon precursor of all steroid hormones. Carbon 59-65 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 11-31 27618127-2 2016 In the reaction, two C(sp(3))-C(sp(2)) bonds are formed on the former hydrazonic carbon generating an all-carbon quaternary stereocenter, and leading to cyclic ketones featuring an alkenyl side chain with complete diastereoselectivity. Carbon 81-87 regulator of calcineurin 2 Homo sapiens 30-37 27571509-0 2016 Isotope-Labeling Studies Support the Electrophilic Compound I Iron Active Species, FeO(3+), for the Carbon-Carbon Bond Cleavage Reaction of the Cholesterol Side-Chain Cleavage Enzyme, Cytochrome P450 11A1. Carbon 107-113 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 184-204 27618127-2 2016 In the reaction, two C(sp(3))-C(sp(2)) bonds are formed on the former hydrazonic carbon generating an all-carbon quaternary stereocenter, and leading to cyclic ketones featuring an alkenyl side chain with complete diastereoselectivity. Carbon 106-112 regulator of calcineurin 2 Homo sapiens 30-37 27571509-1 2016 The enzyme cytochrome P450 11A1 cleaves the C20-C22 carbon-carbon bond of cholesterol to form pregnenolone, the first 21-carbon precursor of all steroid hormones. Carbon 52-58 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 11-31 27571509-1 2016 The enzyme cytochrome P450 11A1 cleaves the C20-C22 carbon-carbon bond of cholesterol to form pregnenolone, the first 21-carbon precursor of all steroid hormones. Carbon 59-65 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 11-31 27620452-6 2016 In order to elucidate the molecular mechanism of GhPEPC1 in the regulation of seed oil content, we quantified the expression of the carbon metabolism related genes of transgenic GhPEPC1 RNAi lines by transcriptome analysis. Carbon 132-138 phosphoenolpyruvate carboxylase 2 Gossypium hirsutum 49-56 27630250-4 2016 The ubiquity of marine rhodopsin photosystems now challenges prior understanding of the nature and contributions of "heterotrophic" bacteria to biogeochemical carbon cycling and energy fluxes. Carbon 159-165 rhodopsin Homo sapiens 23-32 27722548-3 2016 At 5 K, the ground state is composed of large clusters of hydrogen chemisorbed at sp2 carbon sites, on the edges and in voids of the graphene sheets. Carbon 86-92 Sp2 transcription factor Homo sapiens 82-85 27725195-0 2016 Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice. Carbon 77-83 apolipoprotein E Mus musculus 97-101 27657083-1 2016 An easy, but effective, method has been proposed to detect and quantify the Pb(II) in the presence of Cd(II) based on a Bi/glassy carbon electrode (Bi/GCE) with the combination of a back propagation artificial neural network (BP-ANN) and square wave anodic stripping voltammetry (SWASV) without further electrode modification. Carbon 130-136 submaxillary gland androgen regulated protein 3B Homo sapiens 76-82 27132001-0 2016 A fluorometric assay for alkaline phosphatase activity based on beta-cyclodextrin-modified carbon quantum dots through host-guest recognition. Carbon 91-97 alkaline phosphatase, placental Homo sapiens 25-45 27620452-6 2016 In order to elucidate the molecular mechanism of GhPEPC1 in the regulation of seed oil content, we quantified the expression of the carbon metabolism related genes of transgenic GhPEPC1 RNAi lines by transcriptome analysis. Carbon 132-138 phosphoenolpyruvate carboxylase 2 Gossypium hirsutum 178-185 27425251-3 2016 We have demonstrated that the PARP inhibitor (PARPi) AZD2281 is also an effective radiosensitizer for carbon-ion radiation; thus, we speculated that the PARPi could be applied to a wide therapeutic range of linear energy transfer (LET) radiation as a radiosensitizer. Carbon 102-108 poly(ADP-ribose) polymerase 1 Homo sapiens 30-34 27341700-8 2016 This concentration did not seem to cause inhibition of DNA DSB repair but induced a significant G2/M arrest, which was particularly emphasized in p53-null H1299 cells treated with NU7441 and carbon ions. Carbon 191-197 tumor protein p53 Homo sapiens 146-149 27132001-1 2016 A convenient, reliable and highly sensitive assay for alkaline phosphatase (ALP) activity in the real-time manner is developed based on beta-cyclodextrin-modified carbon quantum dots (beta-CD-CQDs) nanoprobe through specific host-guest recognition. Carbon 163-169 alkaline phosphatase, placental Homo sapiens 54-74 27132001-1 2016 A convenient, reliable and highly sensitive assay for alkaline phosphatase (ALP) activity in the real-time manner is developed based on beta-cyclodextrin-modified carbon quantum dots (beta-CD-CQDs) nanoprobe through specific host-guest recognition. Carbon 163-169 alkaline phosphatase, placental Homo sapiens 76-79 27428465-4 2016 The saturated NHC Dipp2 SIm reacted in a 2:2 ratio yielding an NHC ring-expanded product at room temperature forming a six-membered -B-C=N-C=C-N- ring via C-N bond cleavage and further migration of the hydrides from two HBcat molecules to the former carbene-carbon atom. Carbon 16-17 nudix hydrolase 4 Homo sapiens 18-23 27428465-4 2016 The saturated NHC Dipp2 SIm reacted in a 2:2 ratio yielding an NHC ring-expanded product at room temperature forming a six-membered -B-C=N-C=C-N- ring via C-N bond cleavage and further migration of the hydrides from two HBcat molecules to the former carbene-carbon atom. Carbon 65-66 nudix hydrolase 4 Homo sapiens 18-23 27428465-4 2016 The saturated NHC Dipp2 SIm reacted in a 2:2 ratio yielding an NHC ring-expanded product at room temperature forming a six-membered -B-C=N-C=C-N- ring via C-N bond cleavage and further migration of the hydrides from two HBcat molecules to the former carbene-carbon atom. Carbon 65-66 nudix hydrolase 4 Homo sapiens 18-23 27428465-4 2016 The saturated NHC Dipp2 SIm reacted in a 2:2 ratio yielding an NHC ring-expanded product at room temperature forming a six-membered -B-C=N-C=C-N- ring via C-N bond cleavage and further migration of the hydrides from two HBcat molecules to the former carbene-carbon atom. Carbon 258-264 nudix hydrolase 4 Homo sapiens 18-23 27621627-0 2016 Defect density in multiwalled carbon nanotubes influences ovalbumin adsorption and promotes macrophage activation and CD4(+) T-cell proliferation. Carbon 30-36 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 58-67 27488260-2 2016 Functional polymorphisms in genes encoding choline-related one-carbon metabolism enzymes, including phosphatidylethanolamine N-methyltransferase (PEMT), choline dehydrogenase (CHDH) and betaine-homocysteine methyltransferase (BHMT), have important roles in choline metabolism and may thus interact with dietary choline and betaine intake to modify breast cancer risk. Carbon 63-69 phosphatidylethanolamine N-methyltransferase Homo sapiens 100-144 27488260-2 2016 Functional polymorphisms in genes encoding choline-related one-carbon metabolism enzymes, including phosphatidylethanolamine N-methyltransferase (PEMT), choline dehydrogenase (CHDH) and betaine-homocysteine methyltransferase (BHMT), have important roles in choline metabolism and may thus interact with dietary choline and betaine intake to modify breast cancer risk. Carbon 63-69 phosphatidylethanolamine N-methyltransferase Homo sapiens 146-150 27660434-0 2016 Carbon nanotube-based substrates promote cardiogenesis in brown adipose-derived stem cells via beta1-integrin-dependent TGF-beta1 signaling pathway. Carbon 0-6 transforming growth factor beta 1 Homo sapiens 120-129 27385628-0 2016 Self-Assembled Heterojunction Carbon Nanotubes Synergizing with Photoimmobilized IGF-1 Inhibit Cellular Senescence. Carbon 30-36 insulin like growth factor 1 Homo sapiens 81-86 27341700-10 2016 In summary, NSCLC cells irradiated with carbon ions were radio-sensitized by a low concentration of DNA-PK inhibitor NU7441 through a strong G2/M cell cycle arrest. Carbon 40-46 protein kinase, DNA-activated, catalytic subunit Homo sapiens 100-106 27349833-7 2016 Our results show that the food-sourced CNP had various metabolic fluxes through urban systems, with carbon mostly emitted into the air and nitrogen and phosphorus mostly discharged into landfills and water. Carbon 100-106 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 39-42 27182650-1 2016 A novel label-free electrochemical impedance aptasensor based on a gold nanoparticles/double-stranded DNA-graphene (AuNPs/dsDNA-GO) nanocomposite modified glassy carbon electrode was presented for quantitative determination of thrombin. Carbon 162-168 coagulation factor II, thrombin Homo sapiens 227-235 27566173-3 2016 We explored the disulfide conformational isomerization of the Cys14-Cys38 disulfide bond in bovine pancreatic trypsin inhibitor (BPTI), by performing an NMR line-shape analysis of its Cys carbon peaks. Carbon 188-194 trophoblast Kunitz domain protein 1 Bos taurus 110-127 26381241-2 2016 To investigate the intermolecular interaction and binding affinity between the EGF-conjugated DDS and the EGFR, 50 ns molecular dynamics simulations were performed on the complex of tethered EGFR and EGF linked to single-wall carbon nanotube (SWCNT) through a biopolymer chitosan wrapping the tube outer surface (EGFR EGF-CS-SWCNT-Drug complex), and compared to the EGFR EGF complex and free EGFR. Carbon 226-232 epidermal growth factor receptor Homo sapiens 106-110 27604695-0 2016 Carbon Metabolism in Chlamydomonas: Inositol Polyphosphates and TOR Signaling Take Center Stage. Carbon 0-6 RAR related orphan receptor C Homo sapiens 64-67 27558624-6 2016 In the limit of fast exchange (k ex >> Gamma2) the ratio of the apparent proton to carbon methyl PREs, ((1)Hm-Gamma 2 (app) )/((13)Cm-Gamma 2 (app) ), is equal to the square of the ratio of the gyromagnetic ratios of the two nuclei, (gammaEta/gammaC)(2). Carbon 89-95 tryptophanyl-tRNA synthetase 1 Homo sapiens 45-51 27573184-0 2016 Function of RSKS-1-AAK-2-DAF-16 signaling cascade in enhancing toxicity of multi-walled carbon nanotubes can be suppressed by mir-259 activation in Caenorhabditis elegans. Carbon 88-94 mir-259 Caenorhabditis elegans 126-133 27151498-4 2016 Rather, the P-nrP concentration accounted for approximately 79% of PP, and the concentrations of PP, P-rP, and P-nrP were correlated with the particulate organic carbon (POC) concentration (POC vs. PP: r=0.90, p<0.01; POC vs. P-rP: r=0.82, p<0.01; POC vs. P-nrP: r=0.86, p<0.01). Carbon 162-168 prion protein Homo sapiens 111-116 27151498-4 2016 Rather, the P-nrP concentration accounted for approximately 79% of PP, and the concentrations of PP, P-rP, and P-nrP were correlated with the particulate organic carbon (POC) concentration (POC vs. PP: r=0.90, p<0.01; POC vs. P-rP: r=0.82, p<0.01; POC vs. P-nrP: r=0.86, p<0.01). Carbon 162-168 prion protein Homo sapiens 111-116 27573184-2 2016 Previous study has indicated that exposure to multi-walled carbon nanotubes (MWCNTs) dysregulated the transcriptional expression of mir-259. Carbon 59-65 mir-259 Caenorhabditis elegans 132-139 27402831-3 2016 The chain lengths of isoprenoid carbon skeletons vary widely from neryl pyrophosphate (C10) to natural rubber (C>10,000). Carbon 32-38 homeobox C10 Homo sapiens 87-90 27563894-4 2016 The simultaneous and sensitive analysis of CEA and AFP at two screen-printed carbon electrodes was also conducted by our protocol. Carbon 77-83 CEA cell adhesion molecule 3 Homo sapiens 43-46 27563894-4 2016 The simultaneous and sensitive analysis of CEA and AFP at two screen-printed carbon electrodes was also conducted by our protocol. Carbon 77-83 alpha fetoprotein Homo sapiens 51-54 27380897-5 2016 Several carbon-centered radical intermediates, produced by anaerobic incubation of the QDO compounds with N-terminal truncated cytochrome P450 reductase (POR), were characterized using N-tert-butyl-alpha-phenylnitrone (PBN) and 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO) spin traps and were observed by EPR. Carbon 8-14 cytochrome p450 oxidoreductase Homo sapiens 154-157 27459105-5 2016 This is followed by concerted C-Cl bond heterolytic cleavage and proton transfer from Tyr246 to the substrate carbon atom, generating a Co(III) -Cl intermediate. Carbon 30-31 mitochondrially encoded cytochrome c oxidase III Homo sapiens 136-143 27459105-5 2016 This is followed by concerted C-Cl bond heterolytic cleavage and proton transfer from Tyr246 to the substrate carbon atom, generating a Co(III) -Cl intermediate. Carbon 110-116 mitochondrially encoded cytochrome c oxidase III Homo sapiens 136-143 27325450-3 2016 These synthetic analogues would be efficient X-ray crystallographic probes to disclose precise atomic positions of alkyl carbons and lipid-protein interactions in KRN7000/CD1d complexes. Carbon 121-128 CD1d1 antigen Mus musculus 171-175 27468646-4 2016 CAM treatment led to a significant reduction in poly I:C- and RSV-mediated IL-8, CCL5, IFN-beta and -lambda production. Carbon 0-1 C-X-C motif chemokine ligand 8 Homo sapiens 75-79 27323774-7 2016 C-21 lowered BP to a similar degree whether administered before or subsequent to the establishment of Ang II-dependent hypertension. Carbon 0-1 angiotensinogen Rattus norvegicus 102-108 29964739-4 2016 The results showed that the average effluent COD concentration of carbon removal system was 80 mg L-1 when the hydraulic retention time of carbon removal system was 4.5 h. And the subsequent shortcut nitrification system would not be adversely affected by the effluent COD. Carbon 66-72 immunoglobulin kappa variable 1-16 Homo sapiens 98-101 29964739-4 2016 The results showed that the average effluent COD concentration of carbon removal system was 80 mg L-1 when the hydraulic retention time of carbon removal system was 4.5 h. And the subsequent shortcut nitrification system would not be adversely affected by the effluent COD. Carbon 139-145 immunoglobulin kappa variable 1-16 Homo sapiens 98-101 27015767-2 2016 Here, we studied the binding of human serum albumin (HSA), fibrinogen (FBG) and immunoglobulin G (IgG) to PEGylated single-walled carbon nanotubes (PEG-SWCNTs) and evaluated the impact of PEG-SWCNT treated by these proteins on neutrophils in whole blood samples. Carbon 130-136 albumin Homo sapiens 38-51 27299369-3 2016 Additionally, our results indicate that the asymmetry of the hydrogen terminated (1 0 0) diamond C1s core level is an intrinsic aspect of the bulk diamond peak which we have attributed to sub-surface carbon layers. Carbon 200-206 complement C1s Homo sapiens 97-100 27146527-3 2016 The results of total organic carbon (TOC)-normalized PCB concentrations indicate that the sediments have low potential ecological risk in this area. Carbon 29-35 pyruvate carboxylase Homo sapiens 53-56 27311796-8 2016 These results suggest that Nrf2 deficiency induced by HFD promoted hepatic fatty acid metabolism disorder by altering 18-carbon and 22-carbon fatty acid composition. Carbon 120-127 nuclear factor, erythroid derived 2, like 2 Mus musculus 27-31 27311796-8 2016 These results suggest that Nrf2 deficiency induced by HFD promoted hepatic fatty acid metabolism disorder by altering 18-carbon and 22-carbon fatty acid composition. Carbon 121-127 nuclear factor, erythroid derived 2, like 2 Mus musculus 27-31 27294849-2 2016 10-formyl-tetrahydrofolate-dehydrogenase (FDH) is a key regulator for folate availability and metabolic interconversion for the supply of 1-carbon groups. Carbon 140-146 aldehyde dehydrogenase 1 family, member L1 Rattus norvegicus 0-40 27294849-2 2016 10-formyl-tetrahydrofolate-dehydrogenase (FDH) is a key regulator for folate availability and metabolic interconversion for the supply of 1-carbon groups. Carbon 140-146 aldehyde dehydrogenase 1 family, member L1 Rattus norvegicus 42-45 26592091-0 2016 Suppression of basal and carbon nanotube-induced oxidative stress, inflammation and fibrosis in mouse lungs by Nrf2. Carbon 25-31 nuclear factor, erythroid derived 2, like 2 Mus musculus 111-115 27299460-10 2016 Furthermore, treatment with SKT induced extracellular signal-regulated kinases-mediated nuclear factor erythroid-2-related factor 2 (Nrf2) activation as well as the expressions of heme oxygenase 1 and glutamate- cystein ligase catalytic, Nrf2 target genes. Carbon 28-31 nuclear factor, erythroid derived 2, like 2 Mus musculus 133-137 27299460-10 2016 Furthermore, treatment with SKT induced extracellular signal-regulated kinases-mediated nuclear factor erythroid-2-related factor 2 (Nrf2) activation as well as the expressions of heme oxygenase 1 and glutamate- cystein ligase catalytic, Nrf2 target genes. Carbon 28-31 heme oxygenase 1 Mus musculus 180-236 27299460-10 2016 Furthermore, treatment with SKT induced extracellular signal-regulated kinases-mediated nuclear factor erythroid-2-related factor 2 (Nrf2) activation as well as the expressions of heme oxygenase 1 and glutamate- cystein ligase catalytic, Nrf2 target genes. Carbon 28-31 nuclear factor, erythroid derived 2, like 2 Mus musculus 238-242 27278961-4 2016 The exception was C-7, a hydroxylated metabolite, largely formed by CYP2B6 and CYP3A4/5. Carbon 18-19 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 79-85 26983943-0 2016 Pyruvate kinase deletion as an effective phenotype to enhance lysine production in Corynebacterium glutamicum ATCC13032: Redirecting the carbon flow to a precursor metabolite. Carbon 137-143 pyruvate kinase Corynebacterium glutamicum ATCC 13032 0-15 27157732-0 2016 Interaction of some cardiovascular drugs with bovine serum albumin at physiological conditions using glassy carbon electrode: A new approach. Carbon 108-114 albumin Homo sapiens 53-66 27157732-1 2016 In this report, for the first time, the non-modified glassy carbon electrode was used for detection of cardiovascular drug interaction with bovine serum albumin (BSA). Carbon 60-66 albumin Homo sapiens 147-160 27472325-5 2016 Indirectly, as a modulator of the one-carbon metabolism, the AR can affect epigenetic processes, DNA metabolism, and redox balance, all of which are important factors in tumorigenesis. Carbon 38-44 androgen receptor Homo sapiens 61-63 27446401-8 2016 Serum interferon-gamma levels were increased in mice that received DCs pulsed with LM8 cell lysate compared with that in the poly I:C-matured DC group (P<0.041). Carbon 68-69 interferon gamma Mus musculus 6-22 27472325-6 2016 In this review, we focus on the role of AR-signaling on one-carbon metabolism in tumorigenesis. Carbon 60-66 androgen receptor Homo sapiens 40-42 27327860-3 2016 In this study, we observe that the pretreatment of carbon fiber microelectrodes (CFEs) with bovine serum albumin (BSA) would offer a simple but effective strategy to the challenges mentioned above. Carbon 51-57 albumin Homo sapiens 99-112 27504258-1 2016 The goal of this research is to investigate the feasibility of using activated coal-based activated carbon (CBAC) to adsorb Pb(II) from aqueous solutions through batch tests. Carbon 100-106 submaxillary gland androgen regulated protein 3B Homo sapiens 124-130 27345161-0 2016 TOR Signaling Promotes Accumulation of BZR1 to Balance Growth with Carbon Availability in Arabidopsis. Carbon 67-73 target of rapamycin Arabidopsis thaliana 0-3 27345161-9 2016 Such regulation of BZR1 accumulation by glucose-TOR signaling allows carbon availability to control the growth promotion hormonal programs, ensuring supply-demand balance in plant growth. Carbon 69-75 target of rapamycin Arabidopsis thaliana 48-51 27261460-7 2016 Finally, using both co-immunoprecipitation and bimolecular fluorescence complementation, we demonstrated the interaction of Rod1 with Hxt6 and showed that the localization of the Rod1-Hxt6 complex at the plasma membrane is affected by carbon source and is reduced upon overexpression of SNF1 and BMH2. Carbon 235-241 Rod1p Saccharomyces cerevisiae S288C 124-128 27156810-1 2016 In this work, a multiplexed electrochemical immunosensor was developed for sensitive detection of carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) using silver nanoparticles (Ag NPs) or gold nanoparticles (Au NPs) coated-carbon nanospheres (CNSs) as labels. Carbon 231-237 CEA cell adhesion molecule 3 Homo sapiens 98-122 27156810-1 2016 In this work, a multiplexed electrochemical immunosensor was developed for sensitive detection of carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) using silver nanoparticles (Ag NPs) or gold nanoparticles (Au NPs) coated-carbon nanospheres (CNSs) as labels. Carbon 231-237 CEA cell adhesion molecule 3 Homo sapiens 124-127 27156810-1 2016 In this work, a multiplexed electrochemical immunosensor was developed for sensitive detection of carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) using silver nanoparticles (Ag NPs) or gold nanoparticles (Au NPs) coated-carbon nanospheres (CNSs) as labels. Carbon 231-237 alpha fetoprotein Homo sapiens 152-155 27261460-7 2016 Finally, using both co-immunoprecipitation and bimolecular fluorescence complementation, we demonstrated the interaction of Rod1 with Hxt6 and showed that the localization of the Rod1-Hxt6 complex at the plasma membrane is affected by carbon source and is reduced upon overexpression of SNF1 and BMH2. Carbon 235-241 Rod1p Saccharomyces cerevisiae S288C 179-183 27475286-0 2016 Biological effects of double-walled carbon nanotubes on the innate immune system: An in vitro study on THP-1 human monocytes. Carbon 36-42 GLI family zinc finger 2 Homo sapiens 103-108 27037475-4 2016 The capacity to remove As(V) at an initial concentration of 0.2mgL(-1) on the activated carbon electrode at 1.2V was determined to be 2.47x10(-2)mgg(-1), which is 1.8-fold higher than that of As(III) (1.37x10(-2)mgg(-1)). Carbon 88-94 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 23-28 27143563-2 2016 Supercapacitors assembled with this carbon achieve a high energy density of 89 W h kg(-1) (64 W h L(-1) ) and outstanding power density due to the shortened ion-transport distance in 3D. Carbon 36-42 immunoglobulin kappa variable 1-16 Homo sapiens 98-103 28335260-3 2016 In this work, we depict a simple approach to modify chitosan-multi-walled carbon nanotubes-thionine (CS-MWCNTs-THI) hybrid film through one-step electrochemical deposition and the CS-MWCNTs-THI hybrid films are successfully employed to immobilize anti-CEA for fabricating simple, label-free, and highly sensitive electro-chemical immune MEAs. Carbon 74-80 CEA cell adhesion molecule 3 Homo sapiens 252-255 27383050-3 2016 Using genetic interaction mapping, gene co-expression analysis, pathway intermediate quantification and carbon tracing, we uncover a vitamin B12-independent propionate breakdown shunt that is transcriptionally activated on vitamin B12 deficient diets, or under genetic conditions mimicking the human diseases propionic- and methylmalonic acidemia, in which the canonical B12-dependent propionate breakdown pathway is blocked. Carbon 104-110 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 141-144 27383050-3 2016 Using genetic interaction mapping, gene co-expression analysis, pathway intermediate quantification and carbon tracing, we uncover a vitamin B12-independent propionate breakdown shunt that is transcriptionally activated on vitamin B12 deficient diets, or under genetic conditions mimicking the human diseases propionic- and methylmalonic acidemia, in which the canonical B12-dependent propionate breakdown pathway is blocked. Carbon 104-110 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 231-234 27383050-3 2016 Using genetic interaction mapping, gene co-expression analysis, pathway intermediate quantification and carbon tracing, we uncover a vitamin B12-independent propionate breakdown shunt that is transcriptionally activated on vitamin B12 deficient diets, or under genetic conditions mimicking the human diseases propionic- and methylmalonic acidemia, in which the canonical B12-dependent propionate breakdown pathway is blocked. Carbon 104-110 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 231-234 26924399-4 2016 In the current study we found that expression of Mthfd1L, encoding a key component of mitochondrial folate one-carbon metabolism (FOCM), is significantly reduced in ct/ct embryos compared to a partially congenic wild-type strain. Carbon 111-117 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like Mus musculus 49-56 27320042-5 2016 Proteomic and metabolomic analysis highlighted roles for LIN28 in maintaining the low mitochondrial function associated with primed pluripotency and in regulating one-carbon metabolism, nucleotide metabolism, and histone methylation. Carbon 167-173 lin-28 homolog A Homo sapiens 57-62 27306484-2 2016 The calculated results reveal that the most favorable pathway contains four steps, i.e., the nucleophilic attack of NHC on the carbonyl carbon atom of a formyl group, the formation of a Breslow intermediate, a ring-closure process coupled with proton transfer, and regeneration of the catalyst. Carbon 127-133 high mobility group nucleosomal binding domain 4 Homo sapiens 116-119 27383024-4 2016 As described on page 5222, a supercapacitor assembled with this carbon material achieves a high energy density of 89 W h kg(-1) (64 W h L(-1) ) and outstanding power density due to its shortened ion transport distance in three dimensions. Carbon 64-70 immunoglobulin kappa variable 1-16 Homo sapiens 136-141 26853819-5 2016 In this overview, we summarize recent evidence that the enzyme MTHFD1 plays an essential role in FOCM in humans and in mice, and that it determines the partitioning of folate-activated one carbon units between the folate-dependent de novo thymidylate and homocysteine remethylation pathways through its regulated nuclear localization. Carbon 189-195 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 63-69 27188529-2 2016 LCPUFA can be obtained directly from animal foods or synthesized endogenously from 18 carbon precursors via the FADS2 coded enzyme. Carbon 86-92 fatty acid desaturase 2 Homo sapiens 112-117 27372128-0 2016 Rapid adsorption of toxic Pb(II) ions from aqueous solution using multiwall carbon nanotubes synthesized by microwave chemical vapor deposition technique. Carbon 76-82 submaxillary gland androgen regulated protein 3B Homo sapiens 26-32 27043198-0 2016 Ultrafast proton transport in sub-1-nm diameter carbon nanotube porins. Carbon 48-54 SUB1 regulator of transcription Homo sapiens 30-35 27252161-1 2016 Aromatase (estrogen synthetase; EC 1.14.14.1) catalyzes the demethylation of androgens" carbon 19, producing phenolic 18-carbon estrogens. Carbon 88-94 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 0-9 27252161-1 2016 Aromatase (estrogen synthetase; EC 1.14.14.1) catalyzes the demethylation of androgens" carbon 19, producing phenolic 18-carbon estrogens. Carbon 88-94 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 11-30 27252161-1 2016 Aromatase (estrogen synthetase; EC 1.14.14.1) catalyzes the demethylation of androgens" carbon 19, producing phenolic 18-carbon estrogens. Carbon 121-127 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 0-9 27252161-1 2016 Aromatase (estrogen synthetase; EC 1.14.14.1) catalyzes the demethylation of androgens" carbon 19, producing phenolic 18-carbon estrogens. Carbon 121-127 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 11-30 27493209-3 2016 This lesson introduces the core biochemistry of the carbon-fixing reactions of photosynthesis, as well as its variations, C4 and CAM. Carbon 52-58 calmodulin 3 Homo sapiens 129-132 30634204-22 2016 Conclusion In addition to previous phosphorus binders therapy, rhubarb combined medicinal activated carbon could effectively reduce levels of serum phosphorus, calcium-phosphorus product, parathyroid hormone in hemodialysis patients with hyperphos- phatemia, and lessen complications of gastrointestinal tract. Carbon 100-106 parathyroid hormone Homo sapiens 188-207 27154663-0 2016 Sensitive and selective determining ascorbic acid and activity of alkaline phosphatase based on electrochemiluminescence of dual-stabilizers-capped CdSe quantum dots in carbon nanotube-nafion composite. Carbon 169-175 alkaline phosphatase, placental Homo sapiens 66-86 27154663-2 2016 Herein, we found that dual-stabilizers-capped CdSe quantum dots (QDs) in composite film of multi-walled carbon nanotubes (CNTs) and Nafion, displaying eye-visible monochromatic electrochemiluminescence (ECL) with fwhm of 37nm, which offers promising ECL signal for detecting ascorbic acid (AA) as well as the activity of alkaline phosphatase (ALP) in biological samples. Carbon 104-110 alkaline phosphatase, placental Homo sapiens 321-341 27154663-2 2016 Herein, we found that dual-stabilizers-capped CdSe quantum dots (QDs) in composite film of multi-walled carbon nanotubes (CNTs) and Nafion, displaying eye-visible monochromatic electrochemiluminescence (ECL) with fwhm of 37nm, which offers promising ECL signal for detecting ascorbic acid (AA) as well as the activity of alkaline phosphatase (ALP) in biological samples. Carbon 104-110 alkaline phosphatase, placental Homo sapiens 343-346 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 methyl-CpG binding domain protein 1 Homo sapiens 206-210 27458323-4 2016 These library compounds displayed properties more similar to alkaloid natural products than to drugs and commercial drug-like libraries, as shown by a high proportion of sp3 carbon centers. Carbon 174-180 Sp3 transcription factor Homo sapiens 170-173 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 254-260 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 methionine adenosyltransferase 2A Homo sapiens 279-284 28773608-2 2016 The present paper reports the structural and elastic properties of the three-dimensional carbon allotrope I 4 -carbon using first-principles density functional theory. Carbon 89-95 PPP1R2C family member C Homo sapiens 106-109 27251465-1 2016 Cooperative cascade catalysis by bovine serum albumin (BSA)-iodine allows for the first time the performance of C(sp(2))-H sulfenylation of indole from readily available thiophenol (-SH bond) via in situ generation/cleavage of disulfide (S-S bond) in air under aqueous conditions, whereas BSA or I2 individually do not permit this two step sequence to occur in the same pot towards C-S bond formation. Carbon 0-1 albumin Homo sapiens 40-53 27296782-3 2016 The carbonaceous reforming reactions include conversion of CHx (x = 0, 1, 2 and 3) species by hydrogen molecules (H2) to form CHx+2 species or oxidation of C atoms by oxygen molecules to form CO2. Carbon 59-60 xenotropic and polytropic retrovirus receptor 1 Homo sapiens 64-81 27386557-1 2016 Metal-free carbon-based electrocatalysts for dye-sensitized solar cells (DSSCs) are sufficiently active in Co(II)/Co(III) electrolytes but are not satisfactory in the most commonly used iodide/triiodide (I(-)/I3 (-)) electrolytes. Carbon 11-17 mitochondrially encoded cytochrome c oxidase II Homo sapiens 107-113 27386557-1 2016 Metal-free carbon-based electrocatalysts for dye-sensitized solar cells (DSSCs) are sufficiently active in Co(II)/Co(III) electrolytes but are not satisfactory in the most commonly used iodide/triiodide (I(-)/I3 (-)) electrolytes. Carbon 11-17 mitochondrially encoded cytochrome c oxidase III Homo sapiens 114-120 27214647-1 2016 Chiral carbon nanoparticles (CCNPs) were developed by surface passivation using the chiral ligand (-)-sparteine or (+)-sparteine (denoted (-)-SP/CNP and (+)-SP/CNP, respectively). Carbon 7-13 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 30-33 27214647-1 2016 Chiral carbon nanoparticles (CCNPs) were developed by surface passivation using the chiral ligand (-)-sparteine or (+)-sparteine (denoted (-)-SP/CNP and (+)-SP/CNP, respectively). Carbon 7-13 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 145-148 28773608-2 2016 The present paper reports the structural and elastic properties of the three-dimensional carbon allotrope I 4 -carbon using first-principles density functional theory. Carbon 113-119 PPP1R2C family member C Homo sapiens 106-109 28773608-3 2016 The related enthalpy, elastic constants, and phonon spectra confirm that the newly-predicted I 4 -carbon is thermodynamically, mechanically, and dynamically stable. Carbon 100-106 PPP1R2C family member C Homo sapiens 93-96 28773608-4 2016 The calculated mechanical properties indicate that I 4 -carbon has a larger bulk modulus (393 GPa), shear modulus (421 GPa), Young"s modulus (931 GPa), and hardness (55.5 GPa), all of which are all slightly larger than those of c-BN. Carbon 58-64 PPP1R2C family member C Homo sapiens 51-54 28773608-5 2016 The present results indicate that I 4 -carbon is a superhard material and an indirect-band-gap semiconductor. Carbon 41-47 PPP1R2C family member C Homo sapiens 34-37 28773608-6 2016 Moreover, I 4 -carbon shows a smaller elastic anisotropy in its linear bulk modulus, shear anisotropic factors, universal anisotropic index, and Young"s modulus. Carbon 17-23 PPP1R2C family member C Homo sapiens 10-13 27291711-7 2016 Our work highlights the sensitivity of epigenetic networks to one-carbon metabolism due to their common S-adenosylmethionine-dependent transmethylation and has implications for human MTHFD1-associated diseases. Carbon 66-72 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 183-189 27358718-7 2016 The combined network shows that glycolytic enzymes are linked to miRs via p53, c-MYC, HIF1alpha, whereas the genes in serine, glycine and one carbon metabolism are regulated via the c-MYC, as well as other regulatory organization that cannot be observed by investigating individual miRs, TFs, and target genes. Carbon 142-148 tumor protein p53 Homo sapiens 74-77 27427660-2 2016 CEA antibody (anti-CEA) was immobilized onto the surface of glassy carbon electrode through the adsorption effect of Pd-Ir bimetallic nanoparticles modified on the electrode using chitosan. Carbon 67-73 CEA cell adhesion molecule 3 Homo sapiens 0-3 26979315-0 2016 Electrochemical detection of malathion pesticide using acetylcholinesterase biosensor based on glassy carbon electrode modified with conducting polymer film. Carbon 102-108 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-75 26944663-2 2016 For the modified C-S-C-S-L membrane, the contact angle decreased to 35 , the bovine serum albumin (BSA) adsorption mass of static fouling on the membrane surface decreased to 10mug/cm(2), and the secondary water flux recovery rate (FRR) of dynamic fouling of BSA and humic acid (HA) pollutants increased to 98% and 99%, respectively, exhibiting excellent antifouling performance. Carbon 17-18 albumin Homo sapiens 84-97 27427660-2 2016 CEA antibody (anti-CEA) was immobilized onto the surface of glassy carbon electrode through the adsorption effect of Pd-Ir bimetallic nanoparticles modified on the electrode using chitosan. Carbon 67-73 CEA cell adhesion molecule 3 Homo sapiens 19-22 27251132-0 2016 Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-beta-mediated Akt/GSK-3beta/SNAIL-1 signalling pathway. Carbon 13-19 transforming growth factor beta 1 Homo sapiens 124-132 26803590-1 2016 BACKGROUND: Methylenetetrahydrofolate dehydrogenase (MTHFD1) catalyzes three sequential reactions that metabolize derivatives of tetrahydrofolate (THF) in folate-dependent one-carbon metabolism. Carbon 176-182 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 53-59 27251132-0 2016 Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-beta-mediated Akt/GSK-3beta/SNAIL-1 signalling pathway. Carbon 13-19 AKT serine/threonine kinase 1 Homo sapiens 142-145 27251132-0 2016 Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-beta-mediated Akt/GSK-3beta/SNAIL-1 signalling pathway. Carbon 13-19 snail family transcriptional repressor 1 Homo sapiens 156-163 27240625-5 2016 The contribution of DOC to the carbon sequestration in the North Atlantic Ocean (62 Tg-C yr(-1)) is considerable and represents almost a third of the atmospheric CO2 uptake in the region. Carbon 31-37 transglutaminase 2 Homo sapiens 84-88 26510400-7 2016 Sucrose accumulation was also repressed in young fruits and final yield of MDHAR silenced lines showed a stronger decrease under carbon limitation, and the phenotype was partially restored by reducing fruit load. Carbon 129-135 monodehydroascorbate reductase Solanum lycopersicum 75-80 29737675-2 2016 Results showed that the carbon costs in northwest region, southwest region, northeast region, north region and central south and east region were 3.38, 3.64, 1.03, 1.66 and 4.38 Tg C, respectively, totaling 14.09 Tg C. Carbon 24-30 transglutaminase 2 Homo sapiens 178-182 29737675-2 2016 Results showed that the carbon costs in northwest region, southwest region, northeast region, north region and central south and east region were 3.38, 3.64, 1.03, 1.66 and 4.38 Tg C, respectively, totaling 14.09 Tg C. Carbon 24-30 transglutaminase 2 Homo sapiens 213-217 29737675-3 2016 Meanwhile the carbon leakages of the above regions were 21.33, 4.60, 5.50, 1.32 and 3.78 Tg C, respectively, and 36.53 Tg C in total. Carbon 14-20 transglutaminase 2 Homo sapiens 89-93 29737675-7 2016 The carbon cost and carbon leakage of the GGP were 50.62 Tg C in total, which counteracted 19.9% of the sequestered carbon in the program. Carbon 4-10 transglutaminase 2 Homo sapiens 57-61 29737675-7 2016 The carbon cost and carbon leakage of the GGP were 50.62 Tg C in total, which counteracted 19.9% of the sequestered carbon in the program. Carbon 20-26 transglutaminase 2 Homo sapiens 57-61 29737675-7 2016 The carbon cost and carbon leakage of the GGP were 50.62 Tg C in total, which counteracted 19.9% of the sequestered carbon in the program. Carbon 20-26 transglutaminase 2 Homo sapiens 57-61 29737675-9 2016 The net carbon sequestration of the GGP was 203.50 Tg C with an annual average of 18.50 Tg C a-1. Carbon 8-14 transglutaminase 2 Homo sapiens 51-55 27144809-4 2016 The minimum energy pathway shows a resemblance to the well-known double-well potential model for SN2 reactions at carbon. Carbon 114-120 solute carrier family 38 member 5 Homo sapiens 97-100 27145229-2 2016 Human epithelial 15-lipoxygenase-2 (h15-LOX-2), the major lipoxygenase in macrophages, has exhibited strict regiospecificity, catalyzing only the hydroperoxidation of carbon 15 of AA. Carbon 167-173 arachidonate 15-lipoxygenase type B Homo sapiens 37-45 26748372-0 2016 Direct electrochemistry of cytochrome c immobilized on titanium nitride/multi-walled carbon nanotube composite for amperometric nitrite biosensor. Carbon 85-91 cytochrome c, somatic Homo sapiens 27-39 27217700-2 2016 METHODS: Male albino Wistar rats weighing 100-120 g were treated with tetrachloride carbon (CCl4) for 8 wk to induce cirrhosis. Carbon 84-90 C-C motif chemokine ligand 4 Rattus norvegicus 92-96 26748372-4 2016 Direct electrochemistry and electrocatalysis of cytochrome c immobilized on the MWCNTs-TiN composite modified on a glassy carbon electrode for nitrite sensing are investigated. Carbon 122-128 cytochrome c, somatic Homo sapiens 48-60 26735872-4 2016 The Ag@Pb(II)-beta-CD was used as a substrate material to modify glass carbon electrodes and formed a sensing platform for the fabricating ECL immunosensor. Carbon 71-77 submaxillary gland androgen regulated protein 3B Homo sapiens 7-13 27136166-10 2016 Analysis of infrared spectra of the husk ash after absorption of Pb(II) suggested that OH, C=O, C-O, Si-O-Si, and O-Si-O groups were important for the Pb(II) ion removal. Carbon 91-92 submaxillary gland androgen regulated protein 3B Homo sapiens 151-157 26745795-2 2016 Au nanoparticles with biocompatibility were electrodeposited on the surface of glassy carbon electrode (GCE) which can effectively capture and immobilize primary anti-AFP (Ab1) to significantly amplify the electrochemical signal. Carbon 86-92 alpha fetoprotein Homo sapiens 167-170 27079442-0 2016 Highly intense fluorescence of novel carbon nanocrystals combined with a DNAzyme-assisted autocatalytic multiple amplification strategy for sensitive detection of thrombin. Carbon 37-43 coagulation factor II, thrombin Homo sapiens 163-171 27079442-1 2016 In this work, novel water-soluble carbon nanocrystals (CNCs) with excellent fluorescence were prepared, and successfully applied to sensitive fluorescence detection of thrombin by using an enzyme-assisted autocatalytic DNA recycling amplification strategy. Carbon 34-40 coagulation factor II, thrombin Homo sapiens 168-176 27153534-4 2016 Phosphorylation of these enzymes leads to enhanced HK activity to sustain glucose uptake but reduced activity of FBP1 to block the gluconeogenic route and reduced activity of PFK1 and ENO1 to moderate drop of glucose-6-phosphate and to repartition more carbon flux to pentose phosphate pathway (PPP), maintaining cellular energy and redox homeostasis at cellular and organismal levels. Carbon 253-259 hexokinase 1 Homo sapiens 51-53 27064509-3 2016 The addition of CrCl3 to 1-Cr, and FeCl3 to 2-Fe, afforded oxidatively triggered C-C bond formation as rac-2,2"-di(2,6-(i)Pr2C6H3N )2dicyclohexane (EA2) was produced in modest yields. Carbon 16-17 Rac family small GTPase 2 Homo sapiens 103-108 27064509-3 2016 The addition of CrCl3 to 1-Cr, and FeCl3 to 2-Fe, afforded oxidatively triggered C-C bond formation as rac-2,2"-di(2,6-(i)Pr2C6H3N )2dicyclohexane (EA2) was produced in modest yields. Carbon 18-19 Rac family small GTPase 2 Homo sapiens 103-108 26706940-1 2016 A new type of thermo-sensitive receptor carbon dots/SiO2/molecularly imprinted polymer (CDs/SiO2/MIP) was prepared by surface imprinting procedure and the epitope approach. Carbon 40-46 major intrinsic protein of lens fiber Homo sapiens 92-100 27073983-7 2016 The results indicate that the NO3 addition reactions on the aromatic ring of the methoxyphenols are exothermic, with energy values ranging between -13 and -21 kcal mol(-1), depending on the environment of the carbon on which the oxygen atom of NO3 is attached. Carbon 209-215 NBL1, DAN family BMP antagonist Homo sapiens 30-33 27073983-7 2016 The results indicate that the NO3 addition reactions on the aromatic ring of the methoxyphenols are exothermic, with energy values ranging between -13 and -21 kcal mol(-1), depending on the environment of the carbon on which the oxygen atom of NO3 is attached. Carbon 209-215 NBL1, DAN family BMP antagonist Homo sapiens 244-247 27073983-8 2016 These energy values allowed identifying the most suitable carbon sites for the NO3 addition on the aromatic ring of the methoxyphenols: at the exception of the 3-MP, the NO3 ipso-addition to the hydroxyl group is one of the favored sites for all the studies compounds. Carbon 58-64 NBL1, DAN family BMP antagonist Homo sapiens 79-82 27136166-10 2016 Analysis of infrared spectra of the husk ash after absorption of Pb(II) suggested that OH, C=O, C-O, Si-O-Si, and O-Si-O groups were important for the Pb(II) ion removal. Carbon 96-97 submaxillary gland androgen regulated protein 3B Homo sapiens 151-157 27126478-11 2016 Stronger positive associations of black carbon and sulfate with myeloperoxidase were observed among participants with diabetes than in those without. Carbon 40-46 myeloperoxidase Homo sapiens 64-79 26952415-1 2016 A sensitive electrochemical sensor based on bovine serum albumin (BSA)/poly (diallyldimethylammonium chloride) (PDDA) functionalized graphene nanosheets (PDDA-G) composite film modified glassy carbon electrode (BSA/PDDA-G/GCE) had been developed to investigate the oxidative protein damage and protections of protein from damage by flavonoids. Carbon 193-199 albumin Homo sapiens 51-64 26477310-3 2016 Within this cluster the cancer-associated and cardioprotective miR-22 was shown to repress fatty acid synthesis and elongation in tumour cells by targeting ATP citrate lyase and fatty acid elongase 6, as well as impairing mitochondrial one-carbon metabolism by suppression of methylene tetrahydrofolate dehydrogenase/cyclohydrolase. Carbon 240-246 microRNA 22 Homo sapiens 63-69 27028729-3 2016 An N,O-dual doped carbon (denoted as NOC) network is designed and synthesized, which is greatly favorable for sodium storage. Carbon 18-24 nocturnin Homo sapiens 37-40 27141896-7 2016 For an IQR increase in PM2.5, black carbon and PNC100-200, respective increases of 0.17 ng/ml (95% CI: 0.02-0.33), 0.12 ng/ml (95% CI: 0.01-0.24) and 0.13 ng/ml (95% CI:0.02-0.24) in interleukin-8 in EBC reflecting airway inflammation were also observed. Carbon 36-42 C-X-C motif chemokine ligand 8 Homo sapiens 183-196 26867495-5 2016 MPO or activated human neutrophils (by phorbol myristate acetate) catalyzed the oxidation of INH and formed several free radical intermediates; the inclusion of superoxide dismutase revealed a carbon-centered radical which is considered to be the reactive metabolite that binds with NAD(+). Carbon 193-199 myeloperoxidase Homo sapiens 0-3 26918955-2 2016 In these transition-metal-free processes, a Csp(3) -Csp(2) and Csp(3) -H bond are formed on the same carbon atom. Carbon 101-107 regulator of calcineurin 2 Homo sapiens 52-57 27143882-0 2016 Conjugation of insulin onto the sidewalls of single-walled carbon nanotubes through functionalization and diimide-activated amidation. Carbon 59-65 insulin Homo sapiens 15-22 27016434-3 2016 The obtained detection and quantification limits suggest that the in-situ antimony film electrode prepared from carbon nanofibers modified screen-printed electrode (SbSPCE-CNF) produces a better analytical performance as compared to the classical SPCE modified with antimony for Pb(II) and Cd(II) determination, approving its appropriateness for measuring low mug L(-1) levels of the considered metals. Carbon 112-118 submaxillary gland androgen regulated protein 3B Homo sapiens 279-296 26863193-3 2016 Here we use environmental and metagenomic data gathered during the Tara Oceans expedition to improve our understanding of carbon export in the oligotrophic ocean. Carbon 122-128 TRIO and F-actin binding protein Homo sapiens 67-71 27015265-3 2016 Herein, we show the interest of vertically aligned nitrogen-doped carbon nanotube (VA-NCNT) electrodes for the required sensitive electrochemical detection of lysozyme in serum, a protein that is up-regulated in IBD. Carbon 66-72 lysozyme Homo sapiens 159-167 26934203-0 2016 Catalase-Modified Carbon Electrodes: Persuading Oxygen To Accept Four Electrons Rather Than Two. Carbon 18-24 catalase Homo sapiens 0-8 26934203-3 2016 With the immobilization of catalase on the surface, the hydrogen peroxide produced electrochemically is decomposed back to oxygen by the enzyme; the enzyme natural activity on the surface regenerates oxygen, which is further reduced by the carbon electrode with no direct electron transfer between the enzyme and the electrode. Carbon 240-246 catalase Homo sapiens 27-35 26982372-3 2016 Linking benzamide substrates with a rotatable C-N bond, we constructed a novel semirigid pyramid-like scaffold that could support its two-turn alpha-helix mimicry without aromatic stacking interactions and could adopt the different dihedral angles of the key residues of p53 and BH3-only peptides. Carbon 46-47 tumor protein p53 Homo sapiens 271-274 27014926-8 2016 A 2.6 A resolution X-ray crystal structure of a complex between oxalate and the Co(II)-substituted DeltaE162 OxDC variant, in which Glu(162) has been deleted from the active site loop, reveals the likely mode by which the substrate coordinates the catalytically active Mn ion prior to C-C bond cleavage. Carbon 112-113 mitochondrially encoded cytochrome c oxidase II Homo sapiens 80-85 27079438-6 2016 Importantly, the combined adjuvant of poly(I:C) plus LAG-3-Ig downregulated expressions of PD-1, LAG-3, and TIGIT on P1A-specific T cells, indicating prevention of T cell exhaustion. Carbon 45-46 lymphocyte-activation gene 3 Mus musculus 97-102 27050837-6 2016 In the rewetted iron-rich cores, a sharp increase in pore water iron (Fe) concentrations correlated with concentrations of inorganic carbon (TIC, > 13 mmol L-1) and dissolved organic carbon (DOC, > 16 mmol L-1). Carbon 133-139 pleckstrin and Sec7 domain containing 4 Homo sapiens 141-144 30979220-0 2016 Fretting Fatigue Behaviour of Pin-Loaded Thermoset Carbon-Fibre-Reinforced Polymer (CFRP) Straps. Carbon 51-57 dynein light chain LC8-type 1 Homo sapiens 30-33 30979220-1 2016 This paper focuses on the fretting fatigue behaviour of pin-loaded carbon-fibre-reinforced polymer (CFRP) straps studied as models for rigging systems in sailing yachts, for suspenders of arch bridges and for pendent cables in cranes. Carbon 67-73 dynein light chain LC8-type 1 Homo sapiens 56-59 26731195-0 2016 Preparation and evaluation of polyethylenimine-functionalized carbon nanotubes tagged with 5TR1 aptamer for targeted delivery of Bcl-xL shRNA into breast cancer cells. Carbon 62-68 BCL2 like 1 Homo sapiens 129-135 26614453-5 2016 Published and unaltered linear free energy and linear solvation energy relationships for DOC, POC, and particulate black carbon (BC) resulted in predictions that were at best 27% (PCB) and 25% root-mean-square error (RMSE) (PCDD/F) partition fraction compared to observed (using estimated BC/POC fractions of 10 and 25%, respectively). Carbon 121-127 pyruvate carboxylase Homo sapiens 180-183 30052009-2 2016 In this paper, the fluorescence spectroscopy, synchronous fluorescence spectroscopy and circular dichroism spectroscopy) were used to analyze the interaction between four water-soluble carboxyl carbon nanotubes (long-SWCNTs-COOH, short-SWCNTs-COOH, DWCNTs-COOH and MWCNTs-COOH) and human serum albumin. Carbon 194-200 albumin Homo sapiens 288-301 30052009-3 2016 Results showed that the four water-soluble carboxylated carbon nanotubes could quench the intrinsic fluorescence of human serum albumin at different extents. Carbon 56-62 albumin Homo sapiens 122-135 30052009-6 2016 The four water-soluble carboxyl carbon nanotubes could cause slight changes of the CD spectra of human serum albumin as well as the alpha-helix and beta-sheet contents of human serum albumin. Carbon 32-38 albumin Homo sapiens 103-116 30052009-6 2016 The four water-soluble carboxyl carbon nanotubes could cause slight changes of the CD spectra of human serum albumin as well as the alpha-helix and beta-sheet contents of human serum albumin. Carbon 32-38 albumin Homo sapiens 177-190 30052009-7 2016 The above results indicate the fluorescence quenching effect of carbon nanotubes on human serum albumin was related to their structural properties. Carbon 64-70 albumin Homo sapiens 90-103 26900939-12 2016 (13)C-(19)F transferred echo double resonance experiments suggest that sulindac sulfide colocalizes with the Abeta peptide in the aggregate. Carbon 4-5 amyloid beta precursor protein Homo sapiens 109-114 27301189-0 2016 Carbon Nanotube-Mediated Photothermal Disruption of Endosomes/Lysosomes Reverses Doxorubicin Resistance in MCF-7/ADR Cells. Carbon 0-6 ATP binding cassette subfamily B member 1 Homo sapiens 81-103 27064200-4 2016 However, 79HF6 cells and LAN-1 cells were also irradiated by Carbon-UNILAC with LET of 168 keV/mum and Nickel ions with LET of 174 keV/mum, respectively. Carbon 61-67 latexin Homo sapiens 95-98 27076279-3 2016 Because of the layer structure and large specific surface area of SPZP, the SPZP/NAF modified glassy carbon electrode showed high electrocatalytic activity toward the oxidation of rhodamine B. Carbon 101-107 C-X-C motif chemokine ligand 8 Homo sapiens 76-84 26996892-4 2016 Moreover, Hxt11 and Hxt15 are capable of transporting xylitol, a five-carbon polyol derived from xylose, the most abundant pentose in lignocellulosic biomass. Carbon 70-76 hexose transporter HXT15 Saccharomyces cerevisiae S288C 20-25 27064357-7 2016 Carbon limitation of denitrification became evident at elevated NO3-N concentrations (20 mg L(-1)). Carbon 0-6 NBL1, DAN family BMP antagonist Homo sapiens 64-67 26385731-4 2016 For building the interface of the aptasensor, dendritic gold nanoparticles reduced by poly(ethyleneimine) (PEI@DGNPs) were modified on the carbon nanotube-nafion (CNTs-Nf) coated electrode through electrostatic adsorption, which was used not only as matrix for immobilization of thrombin binding aptamer I (TBA I) but also as enhancer to amplify the ECL signal because PEI is an efficient co-reactant of Ru complex. Carbon 139-145 coagulation factor II, thrombin Homo sapiens 279-287 26562331-0 2016 Ultrasensitive non-enzymatic immunosensor for carcino-embryonic antigen based on palladium hybrid vanadium pentoxide/multiwalled carbon nanotubes. Carbon 129-135 CEA cell adhesion molecule 3 Homo sapiens 46-71 26884484-9 2016 These results indicate that the smaller plant sizes observed in aor mutants grown under day/night cycle conditions were attributable to the decrease in carbon utilization during the night. Carbon 152-158 Oxidoreductase, zinc-binding dehydrogenase family protein Arabidopsis thaliana 64-67 26528809-3 2016 Efficient direct electron transfer was successfully achieved for glucose oxidase (GOx) immobilized on the TiO2 NSA/carbon cloth, which produces a stable, mediator-free glucose sensor with good selectivity, high-sensitivity (52 muA mM(-1)cm(-2)), low response time (<5s) and low detection limit (23.4 muM, S/N=3). Carbon 115-121 latexin Homo sapiens 303-306 26861499-2 2016 In this study, we report the development of a solid-state, low-poly(vinyl chloride), carbon-based calcium ion-selective microelectrode (Ca(2+)-ISME), 25 mum in diameter, capable of performing an amperometric approach curve and serving as a potentiometric sensor. Carbon 85-91 latexin Homo sapiens 153-156 32263018-3 2016 This study demonstrated that conjugation of a corticosteroid (triamcinolone) on polyethylene-glycol (PEG)-fabricated multi-walled carbon nanotubes enhances intracellular drug delivery via increased lysosome transport and ultimately suppresses the expression of major pro-inflammatory cytokines (i.e., TNF-alpha, IL-1beta, and IL-6) and matrix metalloproteinase-1 and -3 from fibroblast-like synoviocytes at a very low drug dose. Carbon 130-136 tumor necrosis factor Homo sapiens 301-310 26877080-0 2016 Shoot-to-Root Mobile Transcription Factor HY5 Coordinates Plant Carbon and Nitrogen Acquisition. Carbon 64-70 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 42-45 26877080-5 2016 In the shoot, HY5 promotes carbon assimilation and translocation, whereas in the root, HY5 activation of NRT2.1 expression and nitrate uptake is potentiated by increased carbon photoassimilate (sucrose) levels. Carbon 27-33 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 14-17 26877080-5 2016 In the shoot, HY5 promotes carbon assimilation and translocation, whereas in the root, HY5 activation of NRT2.1 expression and nitrate uptake is potentiated by increased carbon photoassimilate (sucrose) levels. Carbon 27-33 nitrate transporter 2:1 Arabidopsis thaliana 105-109 26877080-6 2016 We further show that HY5 function is fluence-rate modulated and enables homeostatic maintenance of carbon-nitrogen balance in different light environments. Carbon 99-105 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 21-24 26877080-7 2016 Thus, mobile HY5 coordinates light-responsive carbon and nitrogen metabolism, and hence shoot and root growth, in a whole-organismal response to ambient light fluctuations. Carbon 46-52 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 13-16 32263018-4 2016 Specifically, conjugation of triamcinolone and multi-walled carbon nanotubes inactivated nuclear factor-kappaB via inhibition of the phosphorylation of mitogen-activated protein kinases and the serine/threonine kinase Akt. Carbon 60-66 AKT serine/threonine kinase 1 Homo sapiens 218-221 32263018-3 2016 This study demonstrated that conjugation of a corticosteroid (triamcinolone) on polyethylene-glycol (PEG)-fabricated multi-walled carbon nanotubes enhances intracellular drug delivery via increased lysosome transport and ultimately suppresses the expression of major pro-inflammatory cytokines (i.e., TNF-alpha, IL-1beta, and IL-6) and matrix metalloproteinase-1 and -3 from fibroblast-like synoviocytes at a very low drug dose. Carbon 130-136 interleukin 6 Homo sapiens 326-330 26930275-0 2016 Integrated Analysis of Dysregulated ncRNA and mRNA Expression Profiles in Humans Exposed to Carbon Nanotubes. Carbon 92-98 RNANC Homo sapiens 36-41 26820049-0 2016 Facile and Sensitive Fluorescence Sensing of Alkaline Phosphatase Activity with Photoluminescent Carbon Dots Based on Inner Filter Effect. Carbon 97-103 alkaline phosphatase, placental Homo sapiens 45-65 31968788-7 2016 The study indicates that the as-obtained CoNi2 S4 grown on carbon cloth prepared with NO3 - as the anion will be a promising electrode material for supercapacitors. Carbon 59-65 NBL1, DAN family BMP antagonist Homo sapiens 86-89 26706542-2 2016 The Pb(II)-imprinted polymer was synthesized by using 4-vinylpyridine (4VP) as the functional monomer, ethylene glycol dimethacrylate (EGDMA) as the cross-linker, 2,3,5,6-tetra(2-pyridyl) pyrazine (TPPZ) as the chelating agent and magnetic multi-walled carbon nanotubes (MMWCNTs) as the carrier. Carbon 253-259 submaxillary gland androgen regulated protein 3B Homo sapiens 4-10 26814978-2 2016 Rhodamine 6G (R6G) as a Raman reporter is then encapsulated into the nanochannels and anti-epidermal growth factor receptor (EGFR) is conjugated on the nanocomposite surface, defined as anti-EGFR-PEG-rGO@CPSS-Au-R6G, where PEG is polyethylene glycol and CPSS is carbon porous silica nanosheets. Carbon 262-268 epidermal growth factor receptor Homo sapiens 86-123 26814978-2 2016 Rhodamine 6G (R6G) as a Raman reporter is then encapsulated into the nanochannels and anti-epidermal growth factor receptor (EGFR) is conjugated on the nanocomposite surface, defined as anti-EGFR-PEG-rGO@CPSS-Au-R6G, where PEG is polyethylene glycol and CPSS is carbon porous silica nanosheets. Carbon 262-268 epidermal growth factor receptor Homo sapiens 125-129 26842424-3 2016 The stereogenic carbons were elaborated by desymmetrization for C12, allylation for C13, vanadyl-induced epoxidation for C16, Zn(BH4)2 reduction for C17, a chiral building block for C18 and C24, Shi epoxidation for C20 and C21, Myers" alkylation for C22, and thermodynamic control for C25. Carbon 16-23 Bardet-Biedl syndrome 9 Homo sapiens 182-185 26842424-3 2016 The stereogenic carbons were elaborated by desymmetrization for C12, allylation for C13, vanadyl-induced epoxidation for C16, Zn(BH4)2 reduction for C17, a chiral building block for C18 and C24, Shi epoxidation for C20 and C21, Myers" alkylation for C22, and thermodynamic control for C25. Carbon 16-23 TBL1X/Y related 1 Homo sapiens 223-226 26915282-3 2016 This study investigates BP and BZ biodegradation and subsequent carbon flow through the microbial community in PCB-contaminated soil. Carbon 64-70 pyruvate carboxylase Homo sapiens 111-114 26796217-1 2016 A highly atom-economical allylation of oxindoles with vinyl cyclopropanes catalyzed by Pd(PPh3)4 has been developed, setting up a practical venue for the installation of an all-carbon quaternary center at the 3-position in oxindoles under mild reaction conditions. Carbon 177-183 caveolin 1 Homo sapiens 90-94 26903234-0 2016 H18 Carbon: A New Metallic Phase with sp2-sp3 Hybridized Bonding Network. Carbon 4-10 Sp2 transcription factor Homo sapiens 38-41 26903234-0 2016 H18 Carbon: A New Metallic Phase with sp2-sp3 Hybridized Bonding Network. Carbon 4-10 Sp3 transcription factor Homo sapiens 42-45 26820485-0 2016 Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity. Carbon 171-177 alkylmercury lyase Escherichia coli 100-104 26820485-1 2016 In bacterial resistance to mercury, the organomercurial lyase (MerB) plays a key role in the detoxification pathway through its ability to cleave Hg-carbon bonds. Carbon 149-155 alkylmercury lyase Escherichia coli 63-67 26899743-0 2016 Single-Walled Carbon Nanotubes Inhibit the Cytochrome P450 Enzyme, CYP3A4. Carbon 14-20 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 67-73 26899743-1 2016 We report a detailed computational and experimental study of the interaction of single-walled carbon nanotubes (SWCNTs) with the drug-metabolizing cytochrome P450 enzyme, CYP3A4. Carbon 94-100 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 171-177 26796859-1 2016 A bamboo-like nanomaterial composed of V2O5/polyindole (V2O5/PIn) decorated onto the activated carbon cloth was fabricated for supercapacitors. Carbon 95-101 dynein light chain LC8-type 1 Homo sapiens 56-64 26606902-0 2016 Luminescence turn-on/off sensing of biological iron by carbon dots in transferrin. Carbon 55-61 transferrin Homo sapiens 70-81 26606902-4 2016 In the present article we report the pH-dependent luminescence turn-on/off sensing of bound Fe(3+) ions of serum Tf by carbon dots (CDs) with the help of photoluminescence (PL) spectroscopy, FTIR spectroscopy, dynamic light scattering (DLS), circular dichroism (CD) and PL imaging techniques. Carbon 119-125 transferrin Homo sapiens 113-115 26782371-2 2016 Moreover, syn-2-benzyl-4-aryl-3,4-dihydropyrano[3,2-c]chromenes were obtained in high yields (81-86%) via a stereoselective denitrohydrogenation of the corresponding 2-benzylidene-3,4-dihydropyrano[3,2-c]chromenes using a catalytic amount of 10% Pd/C. Carbon 249-250 synapsin II Homo sapiens 10-15 26809548-3 2016 These carbon spheres exhibit a specific capacity of ~210 mA h gCS(-1), with high redox potentials in the voltage range of 2.2-3.7 V vs. Li, when used as positive electrode in lithium cells. Carbon 6-12 mannosyl-oligosaccharide glucosidase Homo sapiens 62-68 26868035-0 2016 Preparation of Au-polydopamine functionalized carbon encapsulated Fe3O4 magnetic nanocomposites and their application for ultrasensitive detection of carcino-embryonic antigen. Carbon 46-52 CEA cell adhesion molecule 3 Homo sapiens 150-175 26663080-7 2016 The serine 215 residue, which is known to regulate the expression of Mxr1p-activated genes in a carbon source-dependent manner, has no role in the Mxr1p-mediated activation of ACS1 expression. Carbon 96-102 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 69-74 26756698-2 2016 It represents a rare C-O bond cleavage of ynamides, as well as a facile and tandem approach for the formation of C-O, C-S, and C-Cl bonds. Carbon 21-22 crystallin gamma E, pseudogene Homo sapiens 127-131 26702556-7 2016 Moreover, the main driving force was identified to be the combination between the very limited solubility of 2-PCB in pure water and the hydrophobic nature of the activated carbon. Carbon 173-179 pyruvate carboxylase Homo sapiens 111-114 26804918-0 2016 The PGC-1alpha/ERRalpha Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Carbon 43-49 PPARG coactivator 1 alpha Homo sapiens 4-14 26804918-0 2016 The PGC-1alpha/ERRalpha Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Carbon 43-49 estrogen related receptor alpha Homo sapiens 15-23 26804918-3 2016 Unexpectedly, the data also reveal that ERRalpha, in concert with PGC-1alpha, negatively regulates the expression of several one-carbon metabolism genes, resulting in substantial perturbations in purine biosynthesis. Carbon 129-135 estrogen related receptor alpha Homo sapiens 40-48 26804918-3 2016 Unexpectedly, the data also reveal that ERRalpha, in concert with PGC-1alpha, negatively regulates the expression of several one-carbon metabolism genes, resulting in substantial perturbations in purine biosynthesis. Carbon 129-135 PPARG coactivator 1 alpha Homo sapiens 66-76 26804918-4 2016 This PGC-1alpha/ERRalpha-mediated repression of one-carbon metabolism promotes the sensitivity of breast cancer cells and tumors to the anti-folate drug methotrexate. Carbon 52-58 PPARG coactivator 1 alpha Homo sapiens 5-15 26804918-4 2016 This PGC-1alpha/ERRalpha-mediated repression of one-carbon metabolism promotes the sensitivity of breast cancer cells and tumors to the anti-folate drug methotrexate. Carbon 52-58 estrogen related receptor alpha Homo sapiens 16-24 26702556-5 2016 In this study, activated carbons were shown to be highly efficient in the adsorption of 2-PCB under static conditions, i.e. at long contact time (several hours) when the adsorption-desorption equilibrium was reached. Carbon 25-32 pyruvate carboxylase Homo sapiens 90-93 26842807-1 2016 We report here that Arabidopsis PROTEIN S-ACYL TRANSFERASE14 (PAT14), through its palmitate transferase activity, acts at the vacuolar trafficking route to repress salicylic acid (SA) signaling, thus mediating age-dependent but not carbon starvation-induced leaf senescence. Carbon 232-238 transferase Arabidopsis thaliana 92-103 26364217-0 2016 Carbon nanoparticle induced cytotoxicity in human mesenchymal stem cells through upregulation of TNF3, NFKBIA and BCL2L1 genes. Carbon 0-6 NFKB inhibitor alpha Homo sapiens 103-109 26364217-0 2016 Carbon nanoparticle induced cytotoxicity in human mesenchymal stem cells through upregulation of TNF3, NFKBIA and BCL2L1 genes. Carbon 0-6 BCL2 like 1 Homo sapiens 114-120 26748870-3 2016 Herein we describe a series of dithioureidodecalin anionophores, in which alkyl substituents on one face are varied from C0 to C10 in two-carbon steps. Carbon 138-144 homeobox C10 Homo sapiens 127-130 26829062-0 2016 Ru(bpy)3(2+)/nanoporous silver-based electrochemiluminescence immunosensor for alpha fetoprotein enhanced by gold nanoparticles decorated black carbon intercalated reduced graphene oxide. Carbon 144-150 alpha fetoprotein Homo sapiens 79-96 26621918-1 2016 The covalent attachment of a 14-carbon aliphatic tail on a glycine residue of nascent translated peptide chains is catalyzed in human cells by two N-myristoyltransferase (NMT) enzymes using the rare myristoyl-CoA (C(14)-CoA) molecule as fatty acid donor. Carbon 32-38 N-myristoyltransferase 1 Homo sapiens 147-169 26621918-1 2016 The covalent attachment of a 14-carbon aliphatic tail on a glycine residue of nascent translated peptide chains is catalyzed in human cells by two N-myristoyltransferase (NMT) enzymes using the rare myristoyl-CoA (C(14)-CoA) molecule as fatty acid donor. Carbon 32-38 N-myristoyltransferase 1 Homo sapiens 171-174 26523648-10 2016 It demonstrates increases of MMPs as the temperature rise from 20 C to 37.8 C. The MMPs of CO2 and n-alkane systems are also found to be proportional to the carbon number in the range of C10 to C14. Carbon 159-165 homeobox C10 Homo sapiens 189-192 26830732-2 2016 Here we report a facile in situ method for preparing three-dimensional porous graphitic carbon composites containing sulfur nanoparticles (3D S@PGC). Carbon 88-94 progastricsin Homo sapiens 144-147 26829062-1 2016 A highly sensitive sandwich-type electrochemiluminescence (ECL) immunosensor was proposed for the quantitative determination of alpha fetoprotein (AFP) using gold nanoparticles decorated black carbon intercalated reduced graphene oxide (Au-rGO@CB) as sensing platform and nanoporous silver (NPS) loaded Ru(bpy)3(2+) as labels. Carbon 193-199 alpha fetoprotein Homo sapiens 128-151 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 116-120 27396133-4 2016 The results showed that the carbon emission and absorption were separately 308.51 Tg C and 11.64 Tg C from 1997 to 2010. Carbon 28-34 transglutaminase 2 Homo sapiens 82-86 27396133-4 2016 The results showed that the carbon emission and absorption were separately 308.51 Tg C and 11.64 Tg C from 1997 to 2010. Carbon 28-34 transglutaminase 2 Homo sapiens 97-101 26368798-0 2016 Interactions between carbon nanodots with human serum albumin and gamma-globulins: The effects on the transportation function. Carbon 21-27 albumin Homo sapiens 48-61 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 26-32 transglutaminase 2 Homo sapiens 17-21 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 17-21 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 116-120 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 116-120 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 17-21 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 116-120 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 116-120 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 17-21 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 116-120 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 116-120 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 17-21 27396133-7 2016 Among the 296.87 Tg C net carbon emission of land use change, carbon emission of remaining land use type was 182.24 Tg C, accounting for 61.4% of the net carbon emission, while the carbon emission of land use transformation was 114.63 Tg C, occupying the rest 38.6% of net carbon emission. Carbon 62-68 transglutaminase 2 Homo sapiens 116-120 26840286-1 2016 A novel series of pyrene containing thiophene monomers TPM1-5 were synthesized and fully characterized by FTIR, MS, 1H- and (13)C-NMR spectroscopy; their thermal properties were determined by TGA and DSC. Carbon 128-129 tropomyosin 1 Homo sapiens 55-61 26695394-1 2016 Sulfur-porous carbon nanotube (S-PCNT) composites are proposed as cathode materials for advanced lithium-sulfur (Li-S) batteries. Carbon 14-20 pericentrin Homo sapiens 33-37 26695394-8 2016 Improved high-rate capability is also delivered by the S-PCNT composites, revealing their potentials as high-performance carbon-sulfur composite cathodes for Li-S batteries. Carbon 121-127 pericentrin Homo sapiens 57-61 26805829-1 2016 In this work, a novel electrochemical sensor was fabricated for determination of amoxicillin in bovine milk samples by decoration of carboxylated multi-walled carbon nanotubes (MWCNTs) with gold nanoparticles (AuNPs) using ethylenediamine (en) as a cross linker (AuNPs/en-MWCNTs). Carbon 159-165 Weaning weight-maternal milk Bos taurus 103-107 26730681-1 2016 In this work, nitrogen-doped carbon nanoparticle (N-CNP) modulated turn-on fluorescent probes were developed for rapid and selective detection of histidine. Carbon 29-35 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 52-55 26805829-0 2016 Construction of an Electrochemical Sensor Based on Carbon Nanotubes/Gold Nanoparticles for Trace Determination of Amoxicillin in Bovine Milk. Carbon 51-57 Weaning weight-maternal milk Bos taurus 136-140 26547269-4 2016 The denitrification rates using optimal carbon-to-nitrate ratios of acidogenic liquid were more than 25 mg NO3-N/(gVSS h). Carbon 40-46 NBL1, DAN family BMP antagonist Homo sapiens 107-110 26748706-1 2016 Lysine acetylation (AcK), a posttranslational modification wherein a two-carbon acetyl group binds covalently to a lysine residue, occurs prominently on mitochondrial proteins and has been linked to metabolic dysfunction. Carbon 73-79 anti-Corynebacterium kutscheri Mus musculus 20-23 26490534-4 2016 Higher bromine substitution and incorporation factors for individual DBP classes were observed for the chlorinated water from the groundwater source (lower concentration of dissolved organic carbon (DOC)), which contained a higher concentration of bromide, than for the surface water source (higher DOC). Carbon 191-197 D-box binding PAR bZIP transcription factor Homo sapiens 69-72 26751681-2 2016 This effect is triggered via activation of the PI3K-Akt-mTOR pathway, and it is usually accompanied by the activation of other metabolic pathways that provide energy and direct the flow of carbon and nitrogen. Carbon 189-195 AKT serine/threonine kinase 1 Homo sapiens 52-55 26793623-6 2015 Systemic administration of poly I:C mobilized CD11c+, F4/80+, and Gr-1(hi) cells from lamina propria and activated NK cells in the mesenteric lymph nodes (MLN) within 24 h. This innate immune cell rearrangement was type I IFN dependent and mediated through upregulation of TLR4 followed by CCR7 expression in these innate immune cells found in the intestinal mucosa. Carbon 34-35 toll-like receptor 4 Mus musculus 273-277 26793623-6 2015 Systemic administration of poly I:C mobilized CD11c+, F4/80+, and Gr-1(hi) cells from lamina propria and activated NK cells in the mesenteric lymph nodes (MLN) within 24 h. This innate immune cell rearrangement was type I IFN dependent and mediated through upregulation of TLR4 followed by CCR7 expression in these innate immune cells found in the intestinal mucosa. Carbon 34-35 chemokine (C-C motif) receptor 7 Mus musculus 290-294 26635402-12 2016 CONCLUSION: For children with in-hospital CPR of >=10 minutes duration, E-CPR was associated with improved survival to hospital discharge and survival with favorable neurological outcome compared with C-CPR. Carbon 0-1 cytochrome p450 oxidoreductase Homo sapiens 42-45 26635402-12 2016 CONCLUSION: For children with in-hospital CPR of >=10 minutes duration, E-CPR was associated with improved survival to hospital discharge and survival with favorable neurological outcome compared with C-CPR. Carbon 0-1 cytochrome p450 oxidoreductase Homo sapiens 77-80 26635402-12 2016 CONCLUSION: For children with in-hospital CPR of >=10 minutes duration, E-CPR was associated with improved survival to hospital discharge and survival with favorable neurological outcome compared with C-CPR. Carbon 0-1 cytochrome p450 oxidoreductase Homo sapiens 77-80 26751681-2 2016 This effect is triggered via activation of the PI3K-Akt-mTOR pathway, and it is usually accompanied by the activation of other metabolic pathways that provide energy and direct the flow of carbon and nitrogen. Carbon 189-195 mechanistic target of rapamycin kinase Homo sapiens 56-60 26626329-0 2016 Comprehensive studies on the nature of interaction between carboxylated multi-walled carbon nanotubes and bovine serum albumin. Carbon 85-91 albumin Homo sapiens 113-126 26742890-3 2016 Herein we develop a variant of a CoPhMoRe screening procedure of single-walled carbon nanotubes (SWCNT) and use it against a panel of human blood proteins, revealing a specific corona phase that recognizes fibrinogen with high selectivity. Carbon 79-85 fibrinogen beta chain Homo sapiens 206-216 26739761-5 2016 The event resulted in a net reduction of 101.54 Tg C in carbon sequestration in the region during these two months, which was 39-53% of the annual net carbon sink of China"s terrestrial ecosystems (190-260 Tg C yr(-1)). Carbon 56-62 transglutaminase 2 Homo sapiens 48-52 26739761-5 2016 The event resulted in a net reduction of 101.54 Tg C in carbon sequestration in the region during these two months, which was 39-53% of the annual net carbon sink of China"s terrestrial ecosystems (190-260 Tg C yr(-1)). Carbon 56-62 transglutaminase 2 Homo sapiens 206-210 26739761-5 2016 The event resulted in a net reduction of 101.54 Tg C in carbon sequestration in the region during these two months, which was 39-53% of the annual net carbon sink of China"s terrestrial ecosystems (190-260 Tg C yr(-1)). Carbon 151-157 transglutaminase 2 Homo sapiens 48-52 26626329-1 2016 Herein, the interaction between carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) and bovine serum albumin has been investigated by using circular dichroism, UV-vis, and fluorescence spectroscopic methods and molecular modeling in order to better understand the basic behavior of carbon nanotubes in biological systems. Carbon 58-64 albumin Homo sapiens 100-113 26626329-1 2016 Herein, the interaction between carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) and bovine serum albumin has been investigated by using circular dichroism, UV-vis, and fluorescence spectroscopic methods and molecular modeling in order to better understand the basic behavior of carbon nanotubes in biological systems. Carbon 287-293 albumin Homo sapiens 100-113 26101900-10 2016 Secondary organic carbon (SOC) formed during long-range transport from the emission sources to the monitoring sites, and the increase of OC2 and OC3 concentrations could be associated with SOC. Carbon 18-24 one cut homeobox 3 Homo sapiens 145-148 26887223-5 2016 The enzyme activities were significantly influenced by acidic pH and the optimum temperature was 30 C. The chitin and cell walls of Sclerotium rolfsii, as carbon sources, supported the maximum and significantly higher chitinase activity by both isolates. Carbon 155-161 endochitinase A Nicotiana tabacum 218-227 26669907-0 2016 The presence of carbon nanostructures in bakery products induces metabolic stress in human mesenchymal stem cells through CYP1A and p53 gene expression. Carbon 16-22 tumor protein p53 Homo sapiens 132-135 25917083-2 2016 GCs act through the glucocorticoid receptor (GR) to coordinate the appropriate cellular response with the primary goal of mobilizing the storage forms of carbon precursors to generate a continuous glucose supply for the brain. Carbon 154-160 nuclear receptor subfamily 3 group C member 1 Homo sapiens 20-43 26241176-1 2016 Combination therapy of carbon-ion beam with the far upstream element-binding protein (FBP)-interacting repressor, FIR, which interferes with DNA damage repair proteins, was proposed as an approach for esophageal cancer treatment with low side effects regardless of TP53 status. Carbon 23-29 tumor protein p53 Homo sapiens 265-269 26324850-7 2016 C-188-9, a small molecule STAT-3 inhibitor, decreased pulmonary fibrosis in the intraperitoneal BLM model as assessed by arterial oxygen saturation (control, 84.4 +- 1.3%; C-188-9, 94.4 +- 0.8%), histology (Ashcroft score: untreated, 5.4 +- 0.25; C-188-9, 3.3 +- 0.14), and attenuated fibrotic markers such as diminished alpha-smooth muscle actin, reduced collagen deposition. Carbon 0-1 signal transducer and activator of transcription 3 Homo sapiens 26-32 25917083-2 2016 GCs act through the glucocorticoid receptor (GR) to coordinate the appropriate cellular response with the primary goal of mobilizing the storage forms of carbon precursors to generate a continuous glucose supply for the brain. Carbon 154-160 nuclear receptor subfamily 3 group C member 1 Homo sapiens 45-47 25395167-0 2016 Fibrinogen enhances the inflammatory response of alveolar macrophages to TiO2, SiO2 and carbon nanomaterials. Carbon 88-94 fibrinogen beta chain Homo sapiens 0-10 28214879-10 2016 Our findings were associated with modified hepatic levels of the mRNAs of several carbon metabolism genes: a reduction of transcripts for liver glucokinase and fatty acid synthase and augmentation of those for carnitine palmitoyl transferase 1 and phosphoenolpyruvate carboxykinase as markers for glycolysis, fatty acid synthesis, beta-oxidation, and gluconeogenesis, respectively. Carbon 82-88 fatty acid synthase Mus musculus 160-179 26573709-5 2016 Both black carbon and fine particulate matter were significantly associated with worsening insulin resistance (0.18 [0.01-0.36] and 0.22 [0.04-0.39] unit increase per SD increase of personal-level black carbon and 0.18 [0.02-0.34] and 0.22 [0.08-0.36] unit increase per SD increase of ambient fine particulate matter on lag days 4 and 5). Carbon 11-17 insulin Homo sapiens 91-98 28078163-1 2016 A catalase-based (NAF/MWCNTs) nanocomposite film modified glassy carbon electrode for hydrogen peroxide (H2O2) detection was developed. Carbon 65-71 catalase Homo sapiens 2-10 28078163-1 2016 A catalase-based (NAF/MWCNTs) nanocomposite film modified glassy carbon electrode for hydrogen peroxide (H2O2) detection was developed. Carbon 65-71 C-X-C motif chemokine ligand 8 Homo sapiens 18-21 26774662-6 2016 When the G2-M phased cells were transferred with DNA-PKcs siRNA and ATM siRNA individually or treated with an inhibitor of either DNA-PKcs or ATM before carbon ion irradiation, the RIBE was effectively diminished. Carbon 153-159 protein kinase, DNA-activated, catalytic subunit Homo sapiens 49-57 26774662-0 2016 G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation. Carbon 85-91 protein kinase, DNA-activated, catalytic subunit Homo sapiens 62-70 25395167-8 2016 We found that FG significantly enhances the cytotoxicity (lactate dehydrogenase leakage) and the inflammatory response (increase in nitric oxide (NO) concentration and NO synthase activation) induced by SiO2, carbon and TiO2 NMs on alveolar macrophages. Carbon 209-215 fibrinogen beta chain Homo sapiens 14-16 26774662-5 2016 Meanwhile, the activity of DNA-PKcs but not ATM was increased in the synchronized G2-M phase cells in spite of both of them were activated in the asynchronous cells after carbon ion irradiation. Carbon 171-177 protein kinase, DNA-activated, catalytic subunit Homo sapiens 27-35 26774662-6 2016 When the G2-M phased cells were transferred with DNA-PKcs siRNA and ATM siRNA individually or treated with an inhibitor of either DNA-PKcs or ATM before carbon ion irradiation, the RIBE was effectively diminished. Carbon 153-159 protein kinase, DNA-activated, catalytic subunit Homo sapiens 130-138 25395167-10 2016 In the case of carbon NMs, the activation of fibrinolysis, likely related to the exposure of cryptic sites of FG, was also observed after 24 h. These findings underline the critical role played by FG in the toxic response to NMs. Carbon 15-21 fibrinogen beta chain Homo sapiens 197-199 27054738-10 2016 For example, ion exchange resin (IX resin) treatment of wastewater to complex and remove PFAS was found to be seven times more efficient when compared to the conventional activated carbon absorption (C-treat) process. Carbon 181-187 phosphoribosylformylglycinamidine synthase Homo sapiens 89-93 26072678-8 2016 Twelve-month post-transplant PTH was reduced but higher in C+ (11.7(6.9-21.2) vs 7.2(4.6-11.2) pmol/L, P < 0.001). Carbon 59-61 parathyroid hormone Homo sapiens 29-32 27445442-1 2016 The collision of two cylindrical hydrogen-free diamond-like carbon (DLC) asperities with approximately 60 % sp3 hybridization has been studied using classical molecular dynamics. Carbon 60-66 Sp3 transcription factor Homo sapiens 108-111 26763345-4 2016 Deletion of MRS3, a component of the iron import machinery, also causes a copper-dependent growth defect on non-fermentable carbon. Carbon 124-130 Fe(2+) transporter Saccharomyces cerevisiae S288C 12-16 26827839-8 2016 Knockdown of STING impaired the IFN-beta response triggered by poly(dA:dT), poly(I:C) or SeV. Carbon 83-84 stimulator of interferon response cGAMP interactor 1 Bos taurus 13-18 26689155-0 2015 Long-term Autophagy and Nrf2 Signaling in the Hippocampi of Developing Mice after Carbon Ion Exposure. Carbon 82-88 nuclear factor, erythroid derived 2, like 2 Mus musculus 24-28 26689155-8 2015 A high nuclear Nrf2 content and low apoptosis level in hippocampal cells subjected to secondary X-rays were observed for the mice exposed to relatively low-LET carbon ions. Carbon 160-166 nuclear factor, erythroid derived 2, like 2 Mus musculus 15-19 26689155-10 2015 Although autophagy was intact, the persistently high nuclear Nrf2 content in the hippocampus might account for the unchanged behavioral pattern in mice exposed to the relatively low-LET carbon ions and the subsequent increased radioresistance of the hippocampus. Carbon 186-192 nuclear factor, erythroid derived 2, like 2 Mus musculus 61-65 26568481-3 2015 We use several theoretical descriptors to categorize these species, focusing our attention on the interaction between the carbene carbon and the methanol oxygen, CcO, because this is the key interaction in the formation of O-ylides, ether products, and O-ylidic solvation complexes. Carbon 130-136 ryanodine receptor 1 Homo sapiens 162-165 26568481-6 2015 We found that the possibility of forming H-bonds among solvent molecules and between the carbene carbon and the hydrogen of the solvent molecule affects the stability, structure and nature of CcO interactions in O-ylides and O-ylidic complexes to the point of generating some diffuse borderlines between these two kinds of species. Carbon 97-103 ryanodine receptor 1 Homo sapiens 192-195 26568380-3 2015 The electrochemical measurements demonstrated that the PtPd-rGONRs composite-modified glassy carbon electrode (GCE) shows much enhanced current signals for TNT reduction, which is 4 and 12-fold higher than rGONRs and bare glassy carbon electrode, respectively. Carbon 93-99 chromosome 16 open reading frame 82 Homo sapiens 156-159 26459451-2 2015 Here, we propose a new solution using a carbon-chain filling strategy to convert C10 terpene and lipids to jet fuel ranged hydrocarbons with aromatic hydrocarbon ingredients in the absence of hydrogen. Carbon 40-46 homeobox C10 Homo sapiens 81-84 26733953-9 2015 Additionally, high and low red fluorescing Prochlorococcus populations (HRF and LRF), co-occurring at the DCM, had similar E k values for their respective substrates, however, maximum assimilation rates, for both leucine and inorganic carbon, were two times greater for HRF cells. Carbon 235-241 CREB3 regulatory factor Homo sapiens 80-83 26600002-4 2015 low turn-on field of 2.62 V/mum with high FE current density of 4.57 mA/cm(2) (corresponding to a applied field of 6.43 V/mum) and prominently high lifetime stability lasting for 1092 min revealing their superiority on comparison with the other commonly used field emitters such as carbon nanotubes, graphene, and zinc oxide nanorods. Carbon 282-288 latexin Homo sapiens 28-31 26629712-4 2015 Nucleus-independent chemical shift was employed to monitor the ionic processes of NaF aqueous electrolyte in nanopores of carbon supercapacitors. Carbon 122-128 C-X-C motif chemokine ligand 8 Homo sapiens 82-85 26679101-6 2015 In mouse models with increasing obesity and insulin resistance, there was an increase in scWAT Delta9 desaturated FAs (SCD ratio) and FAs with 18-carbons (Elovl6 ratio) in mice. Carbon 146-153 insulin Homo sapiens 44-51 26568380-3 2015 The electrochemical measurements demonstrated that the PtPd-rGONRs composite-modified glassy carbon electrode (GCE) shows much enhanced current signals for TNT reduction, which is 4 and 12-fold higher than rGONRs and bare glassy carbon electrode, respectively. Carbon 229-235 chromosome 16 open reading frame 82 Homo sapiens 156-159 26217879-1 2015 Herein, a label free electrochemical aptasensor based on ordered mesoporous carbon-gold nanocomposite modified screen printed electrode has been fabricated for the detection of vascular endothelial growth factor (VEGF165) as a tumor marker. Carbon 76-82 vascular endothelial growth factor A Homo sapiens 177-211 26143467-1 2015 In this study, we reported iminodiacetic acid-copper ion complex (IDA-Cu) immobilized onto gold nanoparticles (GNPs)-modified glassy carbon electrode as a novel electrochemical platform for selective and sensitive determination of lysozyme (Lys). Carbon 133-139 lysozyme Homo sapiens 231-239 26093125-0 2015 Grafted-double walled carbon nanotubes as electrochemical platforms for immobilization of antibodies using a metallic-complex chelating polymer: Application to the determination of adiponectin cytokine in serum. Carbon 22-28 adiponectin, C1Q and collagen domain containing Homo sapiens 181-192 26093125-1 2015 An electrochemical immunosensor for adiponectin (APN) using screen printed carbon electrodes (SPCEs) modified with functionalized double-walled carbon nanotubes (DWCNTs) as platforms for immobilization of the specific antibodies is reported. Carbon 75-81 adiponectin, C1Q and collagen domain containing Homo sapiens 49-52 26453469-4 2015 To synthesise this motif one of the strategies to obtain high conversions from the transaminase/transketolase cascade is the use of hydroxypyruvate (HPA) as a two-carbon donor for the transketolase reaction; although commercially available it is relatively expensive limiting application of the pathway on an industrial scale. Carbon 163-169 transketolase Homo sapiens 96-109 26257187-2 2015 The anode and cathode textiles were prepared by modifying carbon nanotube (CNT)-decorated stretchable textiles with fructose dehydrogenase (FDH) and bilirubin oxidase (BOD), respectively. Carbon 58-64 aldehyde dehydrogenase 1 family member L1 Homo sapiens 116-138 26257187-2 2015 The anode and cathode textiles were prepared by modifying carbon nanotube (CNT)-decorated stretchable textiles with fructose dehydrogenase (FDH) and bilirubin oxidase (BOD), respectively. Carbon 58-64 aldehyde dehydrogenase 1 family member L1 Homo sapiens 140-143 26420843-6 2015 Both FL- and C-whirlin isoforms are required for normal vestibular stereociliary growth, although they may play slightly different roles in the central and peripheral zones of the crista ampullaris. Carbon 13-14 whirlin Mus musculus 15-22 26614056-2 2015 The sensor is based on a thin electroactive poly(melamine) film immobilized on a pre-anodized screen-printed carbon electrode (SPCE*/PME). Carbon 109-115 cystatin B Homo sapiens 133-136 26534875-3 2015 Cu-, Ni-, and Co-based catalytic systems are developed for the coupling of sp-, sp(2) -, and sp(3) -hybridized carbon electrophiles, respectively. Carbon 111-117 Sp2 transcription factor Homo sapiens 80-85 26534875-3 2015 Cu-, Ni-, and Co-based catalytic systems are developed for the coupling of sp-, sp(2) -, and sp(3) -hybridized carbon electrophiles, respectively. Carbon 111-117 Sp3 transcription factor Homo sapiens 93-98 26282439-8 2015 It is well known that total organic carbon plays a role in the transport and redistribution of dl-PCB. Carbon 36-42 pyruvate carboxylase Homo sapiens 98-101 26453469-4 2015 To synthesise this motif one of the strategies to obtain high conversions from the transaminase/transketolase cascade is the use of hydroxypyruvate (HPA) as a two-carbon donor for the transketolase reaction; although commercially available it is relatively expensive limiting application of the pathway on an industrial scale. Carbon 163-169 transketolase Homo sapiens 184-197 26432959-0 2015 Binding studies of hydroxylated Multi-Walled Carbon Nanotubes to hemoglobin, gamma globulin and transferrin. Carbon 45-51 transferrin Homo sapiens 96-107 26000553-4 2015 Fn1 is the first Thaumarchaeota genome without an identifiable carbon fixation pathway, indicating that this mesophilic phylum encompasses more diverse metabolisms than previously thought. Carbon 63-69 fibronectin 1 Homo sapiens 0-3 26432959-2 2015 Herein, we have reported the interaction of three different biological macromolecules such as hemoglobin, gamma globulin and transferrin with hydroxyl group functionalized Multi-Walled Carbon Nanotubes (OH-MWCNTs). Carbon 185-191 transferrin Homo sapiens 125-136 26554020-3 2015 Here the universality of QQS function in modulating carbon and nitrogen allocation is exemplified by a series of transgenic experiments. Carbon 52-58 qua-quine starch Arabidopsis thaliana 25-28 26378686-9 2015 The estimated increases in SBP and DBP were 4.9 mmHg [95% confidence interval (CI) 2.9-6.8] and 3.7 mmHg (95% CI 2.3-5.1) at high elemental carbon level (>=median), and were -1.3 mmHg (95% CI -6.3 to 3.6) and 0.7 mmHg (95% CI -2.8 to 4.2) at low elemental carbon level (<median) per 10 C decrease in daily minimum temperature. Carbon 140-146 D-box binding PAR bZIP transcription factor Homo sapiens 35-38 26378686-9 2015 The estimated increases in SBP and DBP were 4.9 mmHg [95% confidence interval (CI) 2.9-6.8] and 3.7 mmHg (95% CI 2.3-5.1) at high elemental carbon level (>=median), and were -1.3 mmHg (95% CI -6.3 to 3.6) and 0.7 mmHg (95% CI -2.8 to 4.2) at low elemental carbon level (<median) per 10 C decrease in daily minimum temperature. Carbon 259-265 D-box binding PAR bZIP transcription factor Homo sapiens 35-38 26535913-7 2015 Temperature changes of 10.5, 9, and 8 C for AuNRs@C were observed with carbon shell thicknesses of 10, 17, and 25 nm, respectively, at a concentration of 50 muM, after 600 s of irradiation with a laser power of 0.17 W/cm(2). Carbon 72-78 latexin Homo sapiens 158-161 26554020-0 2015 QQS orphan gene regulates carbon and nitrogen partitioning across species via NF-YC interactions. Carbon 26-32 qua-quine starch Arabidopsis thaliana 0-3 26554020-5 2015 Furthermore, transgenic QQS expression increases the protein content of maize, a C4 species (a species that uses 4-carbon photosynthesis), and rice, a protein-poor agronomic crop, both highly divergent from Arabidopsis. Carbon 115-121 qua-quine starch Arabidopsis thaliana 24-27 26554020-2 2015 QQS (Qua-Quine Starch; At3g30720), an orphan gene unique to Arabidopsis thaliana, regulates metabolic processes affecting carbon and nitrogen partitioning among proteins and carbohydrates, modulating leaf and seed composition in Arabidopsis and soybean. Carbon 122-128 qua-quine starch Arabidopsis thaliana 0-3 26554020-2 2015 QQS (Qua-Quine Starch; At3g30720), an orphan gene unique to Arabidopsis thaliana, regulates metabolic processes affecting carbon and nitrogen partitioning among proteins and carbohydrates, modulating leaf and seed composition in Arabidopsis and soybean. Carbon 122-128 qua-quine starch Arabidopsis thaliana 5-21 26554020-10 2015 These findings are, to our knowledge, the first insight into the mechanism of action of QQS in modulating carbon and nitrogen allocation across species. Carbon 106-112 qua-quine starch Arabidopsis thaliana 88-91 26635841-4 2015 BnWRI1 decreased storage carbohydrates and increased soluble sugars to facilitate the carbon flux to lipid anabolism. Carbon 86-92 ethylene-responsive transcription factor WRI1-like Brassica napus 0-6 26169021-6 2015 RESULTS: We found that the IL-6 -174C/G polymorphism might be associated with decreased risk of TB (C vs. G: OR=0.77, 95% CI=0.64-0.91; CG vs. GG: OR=0.72, 95% CI=0.57-0.90; CC+CG vs. GG: OR=0.71, 95% CI=0.57-0.88). Carbon 36-37 interleukin 6 Homo sapiens 27-31 32262887-6 2015 Through modifications to typical chemical vapour deposition (CVD), a high-quality uniform coating of carbon nanotubes (CNTs) is demonstrated over beta-tricalcium phosphate/hydroxyapatite (or TCP/HA), which is in clinical use; and the high-mechanical-strength multicomponent ceramic Ca2ZnSi2O7-ZnAl2O4, (or Sr-HT-Gah). Carbon 101-107 serine peptidase inhibitor Kazal type 1 Homo sapiens 191-194 26561172-3 2015 We confirmed that the damage threshold of the platinum/carbon multilayer with a bilayer period of 3 nm was 0.051 muJ/mum(2), which is sufficiently higher than that in practical applications. Carbon 55-61 latexin Homo sapiens 117-120 26046316-1 2015 This work reports on a facile, novel multianalyte electrochemical immunoassay for simultaneous detection of a-fetoprotein (AFP) and human epidermal growth factor receptor type-2 (HER-2) using metal-containing nanomaterials confined in the ordered mesoporous carbon matrix (OMC-M) as labels. Carbon 258-264 alpha fetoprotein Homo sapiens 108-121 26046316-1 2015 This work reports on a facile, novel multianalyte electrochemical immunoassay for simultaneous detection of a-fetoprotein (AFP) and human epidermal growth factor receptor type-2 (HER-2) using metal-containing nanomaterials confined in the ordered mesoporous carbon matrix (OMC-M) as labels. Carbon 258-264 alpha fetoprotein Homo sapiens 123-126 26046316-1 2015 This work reports on a facile, novel multianalyte electrochemical immunoassay for simultaneous detection of a-fetoprotein (AFP) and human epidermal growth factor receptor type-2 (HER-2) using metal-containing nanomaterials confined in the ordered mesoporous carbon matrix (OMC-M) as labels. Carbon 258-264 erb-b2 receptor tyrosine kinase 2 Homo sapiens 179-184 26569212-5 2015 The sp2 carbons at C-7 and C-7a appeared to be essential for the cytotoxic activities of BPDs. Carbon 8-15 Sp2 transcription factor Homo sapiens 4-7 26423920-3 2015 CS2 activation by silylene 2, however, yields the five-coordinate silicon(IV) complex 13 with a carbon-bound CS2 (2-) ligand, which also represents an unprecedented coordination mode in silicon coordination chemistry. Carbon 96-102 chorionic somatomammotropin hormone 2 Homo sapiens 0-3 26423920-3 2015 CS2 activation by silylene 2, however, yields the five-coordinate silicon(IV) complex 13 with a carbon-bound CS2 (2-) ligand, which also represents an unprecedented coordination mode in silicon coordination chemistry. Carbon 96-102 chorionic somatomammotropin hormone 2 Homo sapiens 109-112 26530409-7 2015 Estimated carbon losses from forest soils suggested that intensive biomass harvests could constitute an important source of carbon transfer from forests to the atmosphere (142-497 Tg-C), partly neutralizing the role of a carbon sink played by forest soils. Carbon 124-130 transglutaminase 2 Homo sapiens 180-184 26530409-7 2015 Estimated carbon losses from forest soils suggested that intensive biomass harvests could constitute an important source of carbon transfer from forests to the atmosphere (142-497 Tg-C), partly neutralizing the role of a carbon sink played by forest soils. Carbon 124-130 transglutaminase 2 Homo sapiens 180-184 26231158-3 2015 We synthesized a series of C-7 substituted 3,4-dihydroisoquinolin-1(2H)-one (dq) analogues designed to selectively inhibit a mutant of PARP10 (LG-PARP10) that contains a unique pocket in its active site. Carbon 27-28 poly(ADP-ribose) polymerase family member 10 Homo sapiens 135-141 26231158-3 2015 We synthesized a series of C-7 substituted 3,4-dihydroisoquinolin-1(2H)-one (dq) analogues designed to selectively inhibit a mutant of PARP10 (LG-PARP10) that contains a unique pocket in its active site. Carbon 27-28 poly(ADP-ribose) polymerase family member 10 Homo sapiens 143-152 26246612-4 2015 AtCOX10 was localized in mitochondria and was able to restore growth of a yeast Deltacox10 null mutant on non-fermentable carbon sources, suggesting that it also participates in haem o synthesis. Carbon 122-128 cytochrome c oxidase 10 Arabidopsis thaliana 0-7 26403272-3 2015 Previously, it has been demonstrated that Tpk1 and Tpk2 are associated with coding regions and promoters of target genes in a carbon source and oxidative stress dependent manner. Carbon 126-132 cAMP-dependent protein kinase catalytic subunit TPK1 Saccharomyces cerevisiae S288C 42-46 26403272-3 2015 Previously, it has been demonstrated that Tpk1 and Tpk2 are associated with coding regions and promoters of target genes in a carbon source and oxidative stress dependent manner. Carbon 126-132 cAMP-dependent protein kinase catalytic subunit TPK2 Saccharomyces cerevisiae S288C 51-55 25391229-3 2015 The two others are located on the rivers Schmiecha and Eyach in the area of the Swabian Alb and were equipped with a powdered activated carbon stage 20 years ago, which was originally aimed at reducing the release of stains from the textile industry. Carbon 136-142 solute carrier family 45 member 2 Danio rerio 88-91 30090267-5 2015 For carbon atoms without an attached hydrogen, a dipolar enhancement usually dominates as we illustrate for sp2 hybridized carbons in the fullerenes, C60 and C70. Carbon 4-10 Sp2 transcription factor Homo sapiens 108-111 30090267-5 2015 For carbon atoms without an attached hydrogen, a dipolar enhancement usually dominates as we illustrate for sp2 hybridized carbons in the fullerenes, C60 and C70. Carbon 123-130 Sp2 transcription factor Homo sapiens 108-111 26165990-7 2015 The enhanced photocatalytic activity of AC-supported Fe-TNTs was related to a synergistic effect of AC adsorption and Fe-TNT photocatalytic ozonation. Carbon 40-42 chromosome 16 open reading frame 82 Homo sapiens 56-59 26176830-1 2015 Vitamin D hydroxylated at carbon 25 (25(OH)D) is generally recognized as a precursor of active vitamin D. Carbon 26-32 cytochrome P450, family 27, subfamily b, polypeptide 1 Mus musculus 33-36 26726618-2 2015 A series of activated carbon aerogels (ACA-X, X = 1, 2, 3, 4, 5, and 6 h) were then prepared by CO2 activation of CA with a variation of activation time (X) for use as an electrode material for supercapacitor. Carbon 22-28 xenotropic and polytropic retrovirus receptor 1 Homo sapiens 39-72 26437241-3 2015 We found that miR-22 was upregulated in lung myeloid dendritic cells (mDCs) of smokers with emphysema and antigen-presenting cells (APCs) of mice exposed to smoke or nanoparticulate carbon black (nCB) through a mechanism that involved the transcription factor NF-kappaB. Carbon 182-188 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 260-269 26311173-6 2015 Importantly, expression of the bdhA gene was found to be specifically induced by (R)-3-HB in a manner dependent on the alternative sigma factor RpoN and the enhancer-binding protein PA2005.This mode of regulation was essential for the utilization of (R)-3-HB as a sole source of energy and carbon. Carbon 290-296 3-hydroxybutyrate dehydrogenase Pseudomonas aeruginosa PAO1 31-35 26311173-6 2015 Importantly, expression of the bdhA gene was found to be specifically induced by (R)-3-HB in a manner dependent on the alternative sigma factor RpoN and the enhancer-binding protein PA2005.This mode of regulation was essential for the utilization of (R)-3-HB as a sole source of energy and carbon. Carbon 290-296 transcriptional regulator Pseudomonas aeruginosa PAO1 182-188 26722253-0 2015 Inhibition of DNA-PKcs enhances radiosensitivity and increases the levels of ATM and ATR in NSCLC cells exposed to carbon ion irradiation. Carbon 115-121 ATR serine/threonine kinase Homo sapiens 85-88 26188334-9 2015 Stimulation of the opening of the non-selective pore in mitochondria correlated with CNP release from mitochondria in parallel with release of cytochrome c, AIF and Endo G. Carbon 42-43 endonuclease G Rattus norvegicus 165-171 26547494-1 2015 An ultrasensitive and highly selective electrochemical sensor for the determination of p-nitrophenol (p-NP) was developed based on electrochemically treated nano polypyrrole/sodium dodecyl sulphate film (ENPPy/SDS film) modified glassy carbon electrode. Carbon 236-242 purine nucleoside phosphorylase Homo sapiens 102-106 26452915-1 2015 In this study, a sensitive and cost-effective electrochemically reduced graphene oxide (ErGO) on graphite reinforced carbon (GRC) was developed for the detection of lead (Pb(II)) ions present in the real-life samples. Carbon 117-123 submaxillary gland androgen regulated protein 3B Homo sapiens 171-177 26452937-0 2015 Novel polydopamine imprinting layers coated magnetic carbon nanotubes for specific separation of lysozyme from egg white. Carbon 53-59 lysozyme Homo sapiens 97-105 26452937-1 2015 Novel core-shell nanocomposites, consisting of magnetic carbon nanotubes (MCNTs) core surrounded by a thin polydopamine (PDA) imprinting shell for specific recognition of lysozyme (Lyz), were fabricated for the first time. Carbon 56-62 lysozyme Homo sapiens 171-179 26081727-1 2015 A two step approach was developed to estimate POC concentrations in a shallow eutrophic lake, where dissolved carbon and inorganic particulate matter strongly influence optical properties. Carbon 110-116 proopiomelanocortin Homo sapiens 46-49 26438849-4 2015 Here we report the identification of an Sptssb mutation, Stellar (Stl), which increased the SPT affinity toward the C18 fatty acyl-CoA substrate by twofold and significantly elevated 20-carbon (C20) LCB production in the mutant mouse brain and eye, resulting in surprising neurodegenerative effects including aberrant membrane structures, accumulation of ubiquitinated proteins on membranes, and axon degeneration. Carbon 186-192 clathrin, light polypeptide (Lcb) Mus musculus 199-202 26412416-5 2015 We additionally unveiled that the barrier height of these SN2 reactions can reliably be predicted not only by the Hirshfeld charge and information gain at the regioselective carbon atom, as previously reported by us for other systems, but also by other information-theoretic descriptors such as Shannon entropy, Fisher information, and Ghosh-Berkowitz-Parr entropy on the same atom. Carbon 174-180 solute carrier family 38 member 5 Homo sapiens 58-61 26594576-1 2015 In the title mol-ecular salt, C12H24N(+) NO3 (-), the cyclohexyl rings adopt chair conformations with the exocyclic C-N bonds in equatorial orientations. Carbon 30-31 NBL1, DAN family BMP antagonist Homo sapiens 41-44 26436557-2 2015 Reaction occurs almost solely by addition of NO3 to the C C double bond and measured yields of beta-hydroxynitrate isomers indicate that 92% of addition occurs at the terminal carbon. Carbon 176-182 NBL1, DAN family BMP antagonist Homo sapiens 45-48 26472156-8 2015 In summary, Notch signaling is activated during PGN+poly(I:C)-induced preterm labor, resulting in upregulation of pro-inflammatory responses, and its inhibition improves in-utero survival of live fetuses. Carbon 59-61 notch receptor 1 Homo sapiens 12-17 26440109-5 2015 Among those Cat8 and Sip4 have overlapping DNA-binding specificity for so-called carbon source responsive elements and induce target genes upon SNF1 activation. Carbon 81-87 Sip4p Saccharomyces cerevisiae S288C 21-25 25985197-0 2015 Interface potential sensing from adsorption of human serum albumin (HSA) on carbon nanotube (CNT) monitored by zero current potentiometry for HSA determination. Carbon 76-82 albumin Homo sapiens 53-66 25985197-1 2015 In this work, the adsorption of human serum albumin (HSA) on the bare multiwall carbon nanotube (MWNT) was investigated by a new electrochemical method, termed as zero current potentiometry. Carbon 80-86 albumin Homo sapiens 38-51 26464061-10 2015 Crude 30-day mortality was 36.1 % in patients with C-R Kp BSI and 23.5 % in those with C-S Kp BSI. Carbon 0-1 CRK proto-oncogene, adaptor protein Homo sapiens 51-57 26182911-2 2015 Scanning Li-nanopipette and probe microscopy (SLi-NPM) is based on a conductive atomic force microscope (AFM) cantilever with an open-ended multi-walled carbon nanotube (MWCNT) affixed to its apex. Carbon 153-159 SHC adaptor protein 2 Homo sapiens 46-49 26372312-8 2015 Our results indicated that organic carbon, element carbon, NO3(-) and NH4(+) might be mainly responsible for the effects of PM2.5 on the decreased NOS2A DNA methylation and elevated FeNO in COPD patients. Carbon 35-41 nitric oxide synthase 2 Homo sapiens 147-152 26372312-8 2015 Our results indicated that organic carbon, element carbon, NO3(-) and NH4(+) might be mainly responsible for the effects of PM2.5 on the decreased NOS2A DNA methylation and elevated FeNO in COPD patients. Carbon 51-57 nitric oxide synthase 2 Homo sapiens 147-152 26440109-6 2015 To analyze the evolution of the Cat8-Sip4 controlled transcriptional network we have compared the response to carbon limitation of Saccharomyces cerevisiae to that of Kluyveromyces lactis. Carbon 110-116 Sip4p Saccharomyces cerevisiae S288C 37-41 26440109-9 2015 We find that in K. lactis, but not in S. cerevisiae, the Sip4 protein plays an essential role in C2 carbon assimilation including induction of the glyoxylate cycle and the carnitine shuttle genes. Carbon 100-106 Sip4p Saccharomyces cerevisiae S288C 57-61 25889348-2 2015 The graphene/SnO2/Au nanocomposite modified glassy carbon electrode was used to immobilize alpha-fetoprotein antibody (anti-AFP) and to construct the immunosensor. Carbon 51-57 alpha fetoprotein Homo sapiens 91-108 26210536-3 2015 This study aimed to assess in vivo the availability of PDE10A in patients with Parkinson"s disease using positron emission tomography molecular imaging with (11)C-IMA107, a highly selective PDE10A radioligand. Carbon 161-162 phosphodiesterase 10A Homo sapiens 55-61 26147366-8 2015 Also, IDO or TRP altered the expression of enzymes that control the availability of carbon atoms for FA synthesis, such as lactate dehydrogenase-A, pyruvate dehydrogenase, glutaminase 1 and glutaminase 2, in a way that inhibits FA synthesis. Carbon 84-90 lactate dehydrogenase A Homo sapiens 123-146 26147366-8 2015 Also, IDO or TRP altered the expression of enzymes that control the availability of carbon atoms for FA synthesis, such as lactate dehydrogenase-A, pyruvate dehydrogenase, glutaminase 1 and glutaminase 2, in a way that inhibits FA synthesis. Carbon 84-90 glutaminase 2 Homo sapiens 172-203 26103880-0 2015 miR-370 and miR-373 regulate the pathogenesis of osteoarthritis by modulating one-carbon metabolism via SHMT-2 and MECP-2, respectively. Carbon 82-88 methyl-CpG binding protein 2 Homo sapiens 115-121 26246317-0 2015 ATR signaling cooperates with ATM in the mechanism of low dose hypersensitivity induced by carbon ion beam. Carbon 91-97 ATR serine/threonine kinase Homo sapiens 0-3 26246317-6 2015 The involvement of ATR pathway in HRS/IRR response was detected with pretreatment of specific inhibitors prior to carbon ion beam. Carbon 114-120 ATR serine/threonine kinase Homo sapiens 19-22 26246317-8 2015 Interestingly, the early G2/M arrest could still be observed in ATM deficient/mutant cells with an effect of ATR signaling, which was discovered to function in an LET-dependent manner, even as low as 0.2Gy for carbon ion radiation. Carbon 210-216 ATR serine/threonine kinase Homo sapiens 109-112 26246317-10 2015 These data demonstrate that ATR pathway may cooperate with ATM in the mechanism of low dose hypersensitivity induced by carbon ion beam. Carbon 120-126 ATR serine/threonine kinase Homo sapiens 28-31 27610002-7 2015 We estimated a gross carbon emission of 56.21 +- 22.5 Tg C from direct combustion of biomass, with an additional 29.4 +- 10 Tg C committed to be emitted in the following years due to dead wood decay. Carbon 21-27 transglutaminase 2 Homo sapiens 54-58 25998161-0 2015 Multiwalled carbon nanotube buckypaper induces cell cycle arrest and apoptosis in human leukemia cell lines through modulation of AKT and MAPK signaling pathways. Carbon 12-18 AKT serine/threonine kinase 1 Homo sapiens 130-133 25889348-2 2015 The graphene/SnO2/Au nanocomposite modified glassy carbon electrode was used to immobilize alpha-fetoprotein antibody (anti-AFP) and to construct the immunosensor. Carbon 51-57 alpha fetoprotein Homo sapiens 124-127 26234249-4 2015 GLNs including boron nitride nanosheets, graphitic-carbon nitride nanosheets and transition metal dichalcogenides (e.g. MoS2 and WS2) have attracted significant interest in numerous research fields from physics and chemistry to biology and engineering, which has led to numerous interdisciplinary advances in nano science. Carbon 41-51 glutamate-ammonia ligase Homo sapiens 0-4 26198379-3 2015 To overcome these limitations, we have developed a new miniaturized electrochemical assay for HcySH in which cytochrome c (cyt c) immobilized on gold nanoparticle (GNP) modified screen printed carbon electrode (SPE) is employed as a biosensing element. Carbon 193-199 cytochrome c, somatic Homo sapiens 109-121 25891177-6 2015 RESULTS: Based on curcumin, we synthesized curcumin analogs with five carbon linkages and established a structure-activity relationship for Nrf2 induction. Carbon 70-76 NFE2 like bZIP transcription factor 2 Homo sapiens 140-144 26301971-4 2015 In the ~6 nm long phR, the ~4 nm 50-carbon conjugated bacterioruberin is bound parallel to the alpha-helices of the peptide backbone. Carbon 36-42 MYC binding protein 2 Homo sapiens 18-21 26198379-3 2015 To overcome these limitations, we have developed a new miniaturized electrochemical assay for HcySH in which cytochrome c (cyt c) immobilized on gold nanoparticle (GNP) modified screen printed carbon electrode (SPE) is employed as a biosensing element. Carbon 193-199 cytochrome c, somatic Homo sapiens 123-128 26219546-0 2015 The molecular and electronic structures of a thioaroyl cation formed by borinium ion-mediated C=S double bond cleavage of CS2. Carbon 94-95 chorionic somatomammotropin hormone 2 Homo sapiens 122-125 26338199-6 2015 RT-PCR Array analysis showed that carbon ion beam combined with CDDP significantly induced apoptosis-related Cytochrome c, almost completely eliminated expression of the CSC markers CD44 and ESA, and significantly inhibited angiogenesis, and metastasis-related HIF1alpha and CD26 compared to carbon ion beam alone, X-ray alone, or X-ray combined with CDDP. Carbon 34-40 cytochrome c, somatic Homo sapiens 109-121 26211519-3 2015 This in combination with the glucose oxidation at the carbon nanotube/Meldola"s blue/glucose dehydrogenase bioanode can result in a current/or power decrease of BFC in the presence of wild-type p53. Carbon 54-60 tumor protein p53 Homo sapiens 194-197 26338199-6 2015 RT-PCR Array analysis showed that carbon ion beam combined with CDDP significantly induced apoptosis-related Cytochrome c, almost completely eliminated expression of the CSC markers CD44 and ESA, and significantly inhibited angiogenesis, and metastasis-related HIF1alpha and CD26 compared to carbon ion beam alone, X-ray alone, or X-ray combined with CDDP. Carbon 34-40 hypoxia inducible factor 1 subunit alpha Homo sapiens 261-270 26338671-0 2015 Carbon ions induce autophagy effectively through stimulating the unfolded protein response and subsequent inhibiting Akt phosphorylation in tumor cells. Carbon 0-6 AKT serine/threonine kinase 1 Homo sapiens 117-120 26338671-6 2015 Furthermore, we demonstrated that high-LET carbon ions stimulated the unfolded protein response (UPR) and mediated autophagy via the UPR-eIF2alpha-CHOP-Akt signaling axis. Carbon 43-49 AKT serine/threonine kinase 1 Homo sapiens 152-155 26338671-7 2015 High-LET carbon ions more severely inhibited Akt-mTOR through UPR to effectively induce autophagy. Carbon 9-15 AKT serine/threonine kinase 1 Homo sapiens 45-48 26338671-7 2015 High-LET carbon ions more severely inhibited Akt-mTOR through UPR to effectively induce autophagy. Carbon 9-15 mechanistic target of rapamycin kinase Homo sapiens 49-53 26340004-0 2015 Delayed Turnover of Unphosphorylated Ssk1 during Carbon Stress Activates the Yeast Hog1 Map Kinase Pathway. Carbon 49-55 mitogen-activated protein kinase kinase kinase SSK1 Saccharomyces cerevisiae S288C 37-41 26340004-0 2015 Delayed Turnover of Unphosphorylated Ssk1 during Carbon Stress Activates the Yeast Hog1 Map Kinase Pathway. Carbon 49-55 mitogen-activated protein kinase HOG1 Saccharomyces cerevisiae S288C 83-87 26269934-8 2015 Overall, concentrations of the fluorescent carbon dots at <=0.1 mg/mL had few adverse effects on the blood components, but at higher doses, the carbon dots impair the structure and function of the blood components, causing morphological disruptions and lysis of red blood cells, interference in the local microenvironments of fibrinogen, activation of the complement system, and disturbances in the plasma and whole blood coagulation function in vitro. Carbon 43-49 fibrinogen beta chain Homo sapiens 329-339 26340004-6 2015 To characterize the mechanism of activation of Hog1 during carbon stress, we examined the turnover of Ssk1 protein levels upon glucose starvation in the presence of cycloheximide and monitored protein levels by western blotting. Carbon 59-65 mitogen-activated protein kinase HOG1 Saccharomyces cerevisiae S288C 47-51 26269934-8 2015 Overall, concentrations of the fluorescent carbon dots at <=0.1 mg/mL had few adverse effects on the blood components, but at higher doses, the carbon dots impair the structure and function of the blood components, causing morphological disruptions and lysis of red blood cells, interference in the local microenvironments of fibrinogen, activation of the complement system, and disturbances in the plasma and whole blood coagulation function in vitro. Carbon 147-153 fibrinogen beta chain Homo sapiens 329-339 26273843-3 2015 Driven by this need, we report the development of PGLa antimicrobial peptide and glutathione conjugated carbon nanotube (CNT) bridged three-dimensional (3D) porous graphene oxide membrane, which can be used for highly efficient disinfection of Escherichia coli O157:H7 bacteria and removal of As(III), As(V), and Pb(II) from water. Carbon 104-110 submaxillary gland androgen regulated protein 3B Homo sapiens 313-319 26716330-2 2015 In this work, we have demonstrated the preparation of new multiwall carbon nanotube (MWNT) incorporate multi-responsive (pH and thermal) gels (MWNT-IPN-MRG) though network formation with functional macromolecules that interact each other via hydrogen bonds, covalent networking and temporary associative forces. Carbon 68-74 MAS1 proto-oncogene like, G protein-coupled receptor Homo sapiens 152-155 26294425-0 2015 SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control. Carbon 14-20 sirtuin 3 Homo sapiens 0-5 26205245-4 2015 This review describes effects of glucose repression on yeast carbon metabolism with a focus on roles of the Snf3/Rgt2 glucose-sensing pathway and Snf1 signal transduction in establishment and relief of glucose repression. Carbon 61-67 glucose sensor Saccharomyces cerevisiae S288C 108-112 26279033-0 2015 Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human Pancreatic Carcinoma Cells MIAPaCa-2 via Rac1 and RhoA Degradation. Carbon 0-6 ras homolog family member A Homo sapiens 120-124 26279033-4 2015 RESULTS: Carbon-ion irradiation reduced the levels of GTP-bound Rac1 and RhoA, 2 major regulators of cell motility, in MIAPaCa-2 cells and GTP-bound Rac1 in AsPC-1 and BxPC-3 cells. Carbon 9-15 ras homolog family member A Homo sapiens 73-77 26254028-8 2015 Our results highlight the variety of CNP products, from sub-10 nm C-dots to ~200 nm sulfur-containing carbon nanostructures, that can be produced over time during the oxidation reaction of the graphenic starting material. Carbon 102-108 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 37-40 26591597-1 2015 In this research we investigated the response of DNA-modified carbon nanotubes in the presence of thrombin and albumin. Carbon 62-68 coagulation factor II, thrombin Homo sapiens 98-106 25978675-0 2015 Understanding the implications of dissolved organic carbon when assessing antagonism in vitro: An example with an estrogen receptor assay. Carbon 52-58 estrogen receptor 1 Homo sapiens 114-131 25448806-1 2015 Effect of poly-dispersed acid-functionalized single-walled carbon nanotubes (AF-SWCNTs) was examined on lipid antigen presentation through CD1d pathway on three cell lines, LA4, MHS, and JAWSII used as prototype antigen presenting cells (APCs). Carbon 59-65 CD1d1 antigen Mus musculus 139-143 26045171-4 2015 Previous studies have focused on the coding region of genes involved in one-carbon metabolism, but recent research demonstrates that an allelic change in a non-coding region of MTRR (rs326119) increases the risk of CHD. Carbon 76-82 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 177-181 26003715-1 2015 A simple and sensitive electroanalytical method was developed for determination of nanomolar levels of Pb(II) based on the voltammetric stripping response at a carbon paste electrode modified with biochar (a special charcoal) and bismuth nanostructures (nBi-BchCPE). Carbon 160-166 submaxillary gland androgen regulated protein 3B Homo sapiens 103-109 26036614-8 2015 Exogenously supplied VLCFA (26 carbons) increased the expression level of ACS1 and induced aerenchyma formation in rcn1 roots. Carbon 31-38 ACC synthase 1 Arabidopsis thaliana 74-78 26352355-5 2015 FN3K phosphorylates fructosamines on the third carbon of their sugar moiety, making them unstable and causing them to detach from proteins, suggesting a protective role of this enzyme. Carbon 47-53 fructosamine 3 kinase Homo sapiens 0-4 26267290-1 2015 The ground state of the molecule consisting of 10 carbon atoms in C10(rg) "ring" conformation and the energy of its metastable C10(st) "star" conformation are reported. Carbon 50-56 homeobox C10 Homo sapiens 66-69 26267290-6 2015 An analysis of possible chemical reactions in carbon plasma involving C10(st) and C10(rg) and leading to the formation of C20 fullerenes was performed. Carbon 46-52 homeobox C10 Homo sapiens 70-73 26267290-6 2015 An analysis of possible chemical reactions in carbon plasma involving C10(st) and C10(rg) and leading to the formation of C20 fullerenes was performed. Carbon 46-52 homeobox C10 Homo sapiens 82-85 26267290-8 2015 It was shown that the presence of hydrogen atoms in carbon plasma and UV radiation accelerate the C10(st) C10(rg) transition and thus suppress the C20 fullerene formation. Carbon 52-58 homeobox C10 Homo sapiens 98-101 26267290-8 2015 It was shown that the presence of hydrogen atoms in carbon plasma and UV radiation accelerate the C10(st) C10(rg) transition and thus suppress the C20 fullerene formation. Carbon 52-58 homeobox C10 Homo sapiens 108-111 26305456-0 2015 CRP-Mediated Carbon Catabolite Regulation of Yersinia pestis Biofilm Formation Is Enhanced by the Carbon Storage Regulator Protein, CsrA. Carbon 13-19 crp Yersinia pestis CO92 0-3 26305456-0 2015 CRP-Mediated Carbon Catabolite Regulation of Yersinia pestis Biofilm Formation Is Enhanced by the Carbon Storage Regulator Protein, CsrA. Carbon 98-104 crp Yersinia pestis CO92 0-3 26305456-6 2015 In accordance with a stark growth defect, deletion of crp in both CO92 and KIM6+ Y. pestis strains significantly impaired biofilm production when solely utilizing alternate carbon sources. Carbon 173-179 crp Yersinia pestis CO92 54-57 26305456-9 2015 Therefore, our findings indicate CRP does not confer a direct stimulatory effect, but may indirectly promote Y. pestis biofilm production by facilitating the alternate carbon source expression profile. Carbon 168-174 crp Yersinia pestis CO92 33-36 26286029-6 2015 The purpose of this study is to investigate the effects of the ATR inhibitor VE-821 in human tumor and normal cells irradiated with high LET carbon ions. Carbon 141-147 ATR serine/threonine kinase Homo sapiens 63-66 26286029-11 2015 CONCLUSIONS: ATR inhibitor would be an effective tumor radiosensitizer with carbon ion irradiation. Carbon 76-82 ATR serine/threonine kinase Homo sapiens 13-16 26068083-0 2015 Correction to "Nanovectorization of TRAIL with Single Wall Carbon Nanotubes Enhances Tumor Cell Killing". Carbon 59-65 TNF superfamily member 10 Homo sapiens 36-41 26014054-0 2015 Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon-carbon bond-forming reactions. Carbon 97-103 high mobility group nucleosomal binding domain 4 Homo sapiens 55-77 26014054-0 2015 Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon-carbon bond-forming reactions. Carbon 97-103 high mobility group nucleosomal binding domain 4 Homo sapiens 79-82 26014054-0 2015 Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon-carbon bond-forming reactions. Carbon 104-110 high mobility group nucleosomal binding domain 4 Homo sapiens 55-77 26014054-0 2015 Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon-carbon bond-forming reactions. Carbon 104-110 high mobility group nucleosomal binding domain 4 Homo sapiens 79-82 26119264-2 2015 The most significant differences are the presence of a hemiketal instead of a trisubstituted double bond and a double bond at C9 and C10 where a saturated carbon chain was expected. Carbon 155-161 homeobox C10 Homo sapiens 133-136 25769179-8 2015 RESULTS: Interquartile range increases in particle number, PM2.5 black carbon, and PM2.5 mass concentrations were associated with significantly lower methylation in the lower tails of the IFN-gamma and ICAM-1 methylation distributions. Carbon 71-77 interferon gamma Homo sapiens 188-197 26339560-0 2015 Adsorption of aqueous Cd(II) and Pb(II) on activated carbon nanopores prepared by chemical activation of doum palm shell. Carbon 53-59 submaxillary gland androgen regulated protein 3B Homo sapiens 22-39 26186018-0 2015 Development of a carbon dot (C-Dot)-linked immunosorbent assay for the detection of human alpha-fetoprotein. Carbon 17-23 alpha fetoprotein Homo sapiens 90-107 26186018-0 2015 Development of a carbon dot (C-Dot)-linked immunosorbent assay for the detection of human alpha-fetoprotein. Carbon 29-30 alpha fetoprotein Homo sapiens 90-107 26186018-1 2015 A sensitive, selective, environmentally friendly, high-throughput, well-plate-based immunosorbent assay was developed to detect human alpha-fetoprotein (AFP) using carbon dots (C-Dots). Carbon 164-170 alpha fetoprotein Homo sapiens 134-151 26186018-1 2015 A sensitive, selective, environmentally friendly, high-throughput, well-plate-based immunosorbent assay was developed to detect human alpha-fetoprotein (AFP) using carbon dots (C-Dots). Carbon 164-170 alpha fetoprotein Homo sapiens 153-156 26271614-4 2015 RESULTS: We show that the MET3 system can only be applied for T. reesei when the cellulase inducing carbon source lactose is used but not when wheat straw, a relevant lignocellulosic substrate for enzyme production, is employed. Carbon 100-106 sulfate adenylyltransferase Saccharomyces cerevisiae S288C 26-30 26172872-2 2015 The carbon backbone of the target compounds was assembled from seven simple fragments by employing two Sonogashira coupling and three SN2 alkynylation reactions. Carbon 4-10 solute carrier family 38 member 5 Homo sapiens 134-137 26252957-0 2015 Correction: Carbon Ion Radiation Inhibits Glioma and Endothelial Cell Migration Induced by Secreted VEGF. Carbon 12-18 vascular endothelial growth factor A Homo sapiens 100-104 26148706-0 2015 Insulin sensitivity index (ISI0, 120) potentially linked to carbon isotopes of breath CO2 for pre-diabetes and type 2 diabetes. Carbon 60-66 insulin Homo sapiens 0-7 25805039-0 2015 Association of folate and other one-carbon related nutrients with hypermethylation status and expression of RARB, BRCA1, and RASSF1A genes in breast cancer patients. Carbon 36-42 retinoic acid receptor beta Homo sapiens 108-112 25805039-2 2015 The present study explored the possible associations of dietary intake of one-carbon metabolism-related nutrients with promoter hypermethylation status and expression of retinoic acid receptor-beta (RARB), breast cancer-1 (BRCA1), and Ras association domain family-1, isoform A (RASSF1A) genes in Iranian women with breast cancer (BC). Carbon 78-84 retinoic acid receptor beta Homo sapiens 170-197 25805039-2 2015 The present study explored the possible associations of dietary intake of one-carbon metabolism-related nutrients with promoter hypermethylation status and expression of retinoic acid receptor-beta (RARB), breast cancer-1 (BRCA1), and Ras association domain family-1, isoform A (RASSF1A) genes in Iranian women with breast cancer (BC). Carbon 78-84 retinoic acid receptor beta Homo sapiens 199-203 25805039-10 2015 One-carbon nutrients most often correlated inversely with the methylation-influenced expression of RARB. Carbon 4-10 retinoic acid receptor beta Homo sapiens 99-103 25284589-10 2015 Hace1(-/-) MEFs exhibit increased Gln uptake and ammonia secretion, and metabolic labeling using (13)C-Gln revealed that Hace1 loss increases incorporation of Gln carbons into the TCA cycle intermediates. Carbon 163-170 HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 Mus musculus 121-126 25896631-4 2015 Both TNF-alpha and IL-1alpha were involved in the gamma-irradiation induced secondary bystander effect but only TNF-alpha contributed to the carbon ion induced response. Carbon 141-147 tumor necrosis factor Homo sapiens 112-121 25822580-4 2015 Co-stimulation with IFN-gamma and the TLR3 ligand poly (I:C) synergistically increased the expression of IFN-beta, IL-6, IL-8, and human beta-defensin-2 in NHEKs compared with poly (I:C) or IFN-gamma alone. Carbon 0-1 interferon gamma Homo sapiens 20-29 25822580-4 2015 Co-stimulation with IFN-gamma and the TLR3 ligand poly (I:C) synergistically increased the expression of IFN-beta, IL-6, IL-8, and human beta-defensin-2 in NHEKs compared with poly (I:C) or IFN-gamma alone. Carbon 0-1 interleukin 6 Homo sapiens 115-119 25822580-4 2015 Co-stimulation with IFN-gamma and the TLR3 ligand poly (I:C) synergistically increased the expression of IFN-beta, IL-6, IL-8, and human beta-defensin-2 in NHEKs compared with poly (I:C) or IFN-gamma alone. Carbon 0-1 C-X-C motif chemokine ligand 8 Homo sapiens 121-125 25822580-4 2015 Co-stimulation with IFN-gamma and the TLR3 ligand poly (I:C) synergistically increased the expression of IFN-beta, IL-6, IL-8, and human beta-defensin-2 in NHEKs compared with poly (I:C) or IFN-gamma alone. Carbon 0-1 interferon gamma Homo sapiens 190-199 26369201-1 2015 The electrochemical oxidation of p-nitrophenol (p-Np) has been studied on glassy carbon electrode modified with the single-walled carbon nanotubes/silver nanowires hybrids (SWNTs-Ag) by using cyclic and differential pulse voltammetry. Carbon 81-87 purine nucleoside phosphorylase Homo sapiens 48-52 26369201-1 2015 The electrochemical oxidation of p-nitrophenol (p-Np) has been studied on glassy carbon electrode modified with the single-walled carbon nanotubes/silver nanowires hybrids (SWNTs-Ag) by using cyclic and differential pulse voltammetry. Carbon 130-136 purine nucleoside phosphorylase Homo sapiens 48-52 26073575-0 2015 Nickel-Catalyzed C-O/C-H Cross-Coupling Reactions for C-C Bond Formation. Carbon 7-8 cochlin Homo sapiens 17-24 26191776-3 2015 In 1 M HClO4 at 23 C, a CTR as low as 0.04 Omega cm(-2) was obtained with only 20 mug cm(-2) Pt and 11 mug cm(-2) Ru using the carbon-supported Ru@Pt with 1:1 Ru:Pt atomic ratio. Carbon 128-134 calcitonin receptor Homo sapiens 25-28 25797928-1 2015 In this work, we investigated and compared carbon nanotubes (CNTs) of different diameters regarding their interaction with bovine serum albumin (BSA) and their ability to alter protein structure. Carbon 43-49 albumin Homo sapiens 130-143 25837300-1 2015 Using a radioactive glutamate uptake assay and immunolabeling, we report that single-walled carbon nanotubes, chemically functionalized with polyethylene glycol (SWCNT-PEG), delivered as a colloidal solute, cause an increase in the uptake of extracellular glutamate by astrocytes and an increase in the immunoreactivity of the glutamate transporter GLAST on their cell surface, which is likely a consequence of an increase in the immunoreactivity of glial fibrillary acidic protein. Carbon 92-98 solute carrier family 1 (glial high affinity glutamate transporter), member 3 Mus musculus 349-354 26141115-4 2015 In the current study we investigated the influence of carbon nanoparticles on the sensitization of animals to ovalbumin via the airways. Carbon 54-60 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 110-119 26141115-6 2015 METHODS: Balb/c mice were repetitively exposed to the antigen ovalbumin after induction of airway inflammation by carbon nanoparticles, either in the presence or in the absence of ectoine. Carbon 114-120 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 62-71 26141115-9 2015 RESULTS: Animals exposed to antigen in the presence of carbon nanoparticles showed increased effects with respect to ovalbumin sensitization, to the allergic airway inflammation after challenge, and to the specific TH2 response in the lymph nodes. Carbon 55-61 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 117-126 25953778-1 2015 Amyloid-beta, a hallmark of Alzheimer"s disease, begins accumulating up to two decades before the onset of dementia, and can be detected in vivo applying amyloid-beta positron emission tomography tracers such as carbon-11-labelled Pittsburgh compound-B. Carbon 212-218 amyloid beta precursor protein Homo sapiens 0-12 25953778-1 2015 Amyloid-beta, a hallmark of Alzheimer"s disease, begins accumulating up to two decades before the onset of dementia, and can be detected in vivo applying amyloid-beta positron emission tomography tracers such as carbon-11-labelled Pittsburgh compound-B. Carbon 212-218 amyloid beta precursor protein Homo sapiens 154-166 26091443-4 2015 Direct and dry deposited carbon nanotube film doped with MoO(x) functions as an electron-blocking transparent electrode, and its performance is enhanced further by overcoating with PEDOT: PSS. Carbon 25-31 PSS Homo sapiens 188-191 26373045-0 2015 Bone Marrow Stem Cells Response to Collagen/Single-Wall Carbon Nanotubes-COOHs Nanocomposite Films with Transforming Growth Factor Beta 1. Carbon 56-62 transforming growth factor, beta 1 Rattus norvegicus 104-137 25349205-2 2015 The orally administered spherical carbon adsorbent AST-120 reduces systemic toxin absorption through gastrointestinal sequestration, which may slow disease progression in these patients. Carbon 34-40 solute carrier family 17 member 5 Homo sapiens 51-54 25648260-5 2015 Gene-gene interactions within one-carbon metabolic pathway were observed in CAD (GCPII 1561 C>T, SHMT 1420 C>T and MTHFR 677 C>T) and PD (cSHMT 1420 C>T, MTRR 66 A>G and RFC1 80 G>A). Carbon 34-40 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 154-158 26137220-11 2015 CONCLUSIONS: Although PDH suppression substantially alters central carbon metabolism, the data indicate that rapid cell proliferation occurs independently of PDH activity. Carbon 67-73 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 22-25 25869931-5 2015 Activity of the Phr peptide system is not seen when pneumococcal cells are grown with glucose, the preferred carbon source and the most prevalent sugar encountered by S. pneumoniae during invasive disease. Carbon 109-115 MYC binding protein 2 Homo sapiens 16-19 25869931-6 2015 Thus, the lantibiotic genes are expressed under the control of both cell density signals via the Phr peptide system and nutritional signals from the carbon source present, suggesting that quorum sensing and the lantibiotic machinery may help pneumococcal cells compete for space and resources during colonization of the nasopharynx. Carbon 149-155 MYC binding protein 2 Homo sapiens 97-100 26025536-8 2015 Subsequently, the glyceraldehydes 3-phosphate dehydrogenase beta subunit (GAPB) involved in carbon fixation was selected and its role in salt tolerance was clarified by over-expressing it in Arabidopsis. Carbon 92-98 glyceraldehyde-3-phosphate dehydrogenase B subunit Arabidopsis thaliana 18-72 26025536-8 2015 Subsequently, the glyceraldehydes 3-phosphate dehydrogenase beta subunit (GAPB) involved in carbon fixation was selected and its role in salt tolerance was clarified by over-expressing it in Arabidopsis. Carbon 92-98 glyceraldehyde-3-phosphate dehydrogenase B subunit Arabidopsis thaliana 74-78 25882421-1 2015 Two novel sensors based on human serum albumin (HSA)-ionic liquid (IL) and bovine serum albumin (BSA)-ionic liquid (IL) composites modified glassy carbon electrode (GCE) were produced for simultaneous determination of water soluble vitamins B2, B6 and C in human plasma following analytes focusing by IL micelles collapse (AFILMC). Carbon 147-153 albumin Homo sapiens 82-95 26137220-1 2015 BACKGROUND: Pyruvate dehydrogenase (PDH) occupies a central node of intermediary metabolism, converting pyruvate to acetyl-CoA, thus committing carbon derived from glucose to an aerobic fate rather than an anaerobic one. Carbon 144-150 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 12-34 26137220-1 2015 BACKGROUND: Pyruvate dehydrogenase (PDH) occupies a central node of intermediary metabolism, converting pyruvate to acetyl-CoA, thus committing carbon derived from glucose to an aerobic fate rather than an anaerobic one. Carbon 144-150 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 36-39 25905497-2 2015 In the sensing strategy, an anti-lysozyme aptamer was immobilized onto the carbon electrode surface by covalent binding via diazonium salt chemistry. Carbon 75-81 lysozyme Homo sapiens 33-41 26273324-1 2015 BACKGROUND: Evidence from several recent metabolomic studies suggests that increased concentrations of triacylglycerols with shorter (14-16 carbon atoms), saturated fatty acids are associated with insulin resistance and the risk of type 2 diabetes. Carbon 140-146 insulin Homo sapiens 197-204 25978143-5 2015 Improved capacitance performance was successfully realized for the ASC (Co3O4//carbon), better than those of the SSCs based on nanoporous carbon and nanoporous Co3O4 materials (i.e., carbon//carbon and Co3O4//Co3O4). Carbon 79-85 PYD and CARD domain containing Homo sapiens 67-70 26056268-8 2015 The preferred substrate of the CYP4F22 was fatty acids with a carbon chain length of 28 or more (>=C28). Carbon 62-68 cytochrome P450 family 4 subfamily F member 22 Homo sapiens 31-38 26018983-4 2015 The next step is a nucleophilic attack on the olefin carbon of SylA by the negatively charged Thr1-O(gamma) atom. Carbon 53-59 thyroid hormone receptor beta Homo sapiens 94-98 26018983-5 2015 The last step is a proton transfer from Thr1-N(z) to another olefin carbon of SylA to complete the inhibition reaction process. Carbon 68-74 thyroid hormone receptor beta Homo sapiens 40-44 26855678-6 2016 In this study, the number of carbon atoms in the fullerenes was used as an index to establish a relationship between the structures of neurotransmitters (NTs) acetylcholine (AC) 1, dopamine (DP) 2, serotonin (SE) 3, and epinephrine (EP) 4 as the well-known redox systems and fullerenes C n (n = 60, 70, 76, 82, and 86) which create [NT].Cn; A-1 to A-5 up to D-1 to D-5. Carbon 29-35 BCL2 related protein A1 Homo sapiens 341-351 26855678-7 2016 The relationship between the number of carbon atoms and the free energy of electron transfer (DeltaG et(n); n = 1-4) is assessed using the Rehm-Weller equation for A-1 to A-5 up to D-1 to D-5 supramolecular [NT].Cn complexes. Carbon 39-45 BCL2 related protein A1 Homo sapiens 164-174 25594160-0 2015 Efficient immobilization of acetylcholinesterase onto amino functionalized carbon nanotubes for the fabrication of high sensitive organophosphorus pesticides biosensors. Carbon 75-81 acetylcholinesterase (Cartwright blood group) Homo sapiens 28-48 26005759-0 2015 Application of Europium Multiwalled Carbon Nanotubes as Novel Luminophores in an Electrochemiluminescent Aptasensor for Thrombin Using Multiple Amplification Strategies. Carbon 36-42 coagulation factor II, thrombin Homo sapiens 120-128 26052987-1 2015 TYW1 catalyzes the formation of 4-demethylwyosine via the condensation of N-methylguanosine (m1G) with carbons 2 and 3 of pyruvate. Carbon 103-110 tRNA-yW synthesizing protein 1 homolog Homo sapiens 0-4 25594160-1 2015 This work introduced an efficient immobilization of acetylcholinesterase (AChE) onto amino functionalized carbon nanotubes (CNT-NH2), in order to fabricate high sensitive and practical organophosphorus pesticide (OPs) biosensors. Carbon 106-112 acetylcholinesterase (Cartwright blood group) Homo sapiens 52-72 25594160-1 2015 This work introduced an efficient immobilization of acetylcholinesterase (AChE) onto amino functionalized carbon nanotubes (CNT-NH2), in order to fabricate high sensitive and practical organophosphorus pesticide (OPs) biosensors. Carbon 106-112 acetylcholinesterase (Cartwright blood group) Homo sapiens 74-78 26066737-0 2015 Wrapping cytochrome c around single-wall carbon nanotube: engineered nanohybrid building blocks for infrared detection at high quantum efficiency. Carbon 41-47 cytochrome c, somatic Homo sapiens 9-21 25747357-3 2015 Daily concentrations of organic carbon (OC) and elemental carbon (EC) were detected 7.3 and 2.5 mug m(-3) in TSP and 5.2 and 2.0 mug m(-3) in PM2.5, which accounted 5.8% and 2.0% of TSP while 5.6% and 2.2% for PM2.5, respectively. Carbon 32-38 thrombospondin 1 Homo sapiens 109-112 25747357-3 2015 Daily concentrations of organic carbon (OC) and elemental carbon (EC) were detected 7.3 and 2.5 mug m(-3) in TSP and 5.2 and 2.0 mug m(-3) in PM2.5, which accounted 5.8% and 2.0% of TSP while 5.6% and 2.2% for PM2.5, respectively. Carbon 58-64 thrombospondin 1 Homo sapiens 109-112 26076355-8 2015 Consequently, the expression of genes that determine osteoblast phenotype, such as alkaline phosphatase, type I collagen, and osteocalcin, was accelerated on carbon nanotube embedded polymer matrix after 14 days. Carbon 158-164 bone gamma-carboxyglutamate protein Homo sapiens 105-137 29511504-6 2015 Mapping the reactivity centers with Pd markers provided unique information about the reactivity of the graphene layers and showed that >2000 reactive centers can be located per 1 mum2 of the surface area of the carbon material. Carbon 214-220 period circadian regulator 1 Homo sapiens 176-186 25938658-5 2015 The evidence gathered here indicates that SRN1 mechanism is operating in this case with the formation of radical anion as a critical step, followed by heterolytic cleavage of a carbon-halogen bond. Carbon 177-183 NPHS2 stomatin family member, podocin Homo sapiens 42-46 26081279-3 2015 Although dug2 showed constitutive transcription, dug1 and dug3 were induced by carbon and nitrogen starvation and yeast extract did not caused significant changes in their relative transcription. Carbon 79-85 metallodipeptidase Saccharomyces cerevisiae S288C 49-53 26081279-3 2015 Although dug2 showed constitutive transcription, dug1 and dug3 were induced by carbon and nitrogen starvation and yeast extract did not caused significant changes in their relative transcription. Carbon 79-85 glutamine amidotransferase subunit DUG3 Saccharomyces cerevisiae S288C 58-62 26030232-2 2015 Here we predict a new carbon allotrope, bct-C12 with the body-centered tetragonal I4/mcm symmetry, from the compression of carbon nanotubes. Carbon 22-28 PPP1R2C family member C Homo sapiens 82-88 25716920-3 2015 The 3- and 4-position carbons are the newly formed chiral carbons because the 5-position carbon of D-FBP comes from the 2-position of D-GAP. Carbon 22-29 ECB2 Homo sapiens 101-104 25716920-3 2015 The 3- and 4-position carbons are the newly formed chiral carbons because the 5-position carbon of D-FBP comes from the 2-position of D-GAP. Carbon 58-65 ECB2 Homo sapiens 101-104 25716920-3 2015 The 3- and 4-position carbons are the newly formed chiral carbons because the 5-position carbon of D-FBP comes from the 2-position of D-GAP. Carbon 22-28 ECB2 Homo sapiens 101-104 26601362-10 2015 Meanwhile, its concentrations are generally higher than the C-H bond of sp3 hybridization in the samples. Carbon 60-61 Sp3 transcription factor Homo sapiens 72-75 25721143-6 2015 Multiple regression results suggest that PFAS levels in the dissolved phase and sediment characteristics (organic carbon fraction and grain size) may be significant controlling factors of PFAS levels in the sediment. Carbon 114-120 phosphoribosylformylglycinamidine synthase Homo sapiens 41-45 26030232-2 2015 Here we predict a new carbon allotrope, bct-C12 with the body-centered tetragonal I4/mcm symmetry, from the compression of carbon nanotubes. Carbon 123-129 PPP1R2C family member C Homo sapiens 82-88 25721143-6 2015 Multiple regression results suggest that PFAS levels in the dissolved phase and sediment characteristics (organic carbon fraction and grain size) may be significant controlling factors of PFAS levels in the sediment. Carbon 114-120 phosphoribosylformylglycinamidine synthase Homo sapiens 188-192 25855791-8 2015 High intermolecular non-competitive kinetic deuterium isotope effects on both kcat and kcat/Km, from 5 to 11, were observed with both substrates, indicative of rate-limiting C-H bond cleavage and suggesting that the juxtaposition of the C21 carbon in the active site is critical for efficient oxidation. Carbon 241-247 TBL1X/Y related 1 Homo sapiens 237-240 25849107-1 2015 The amperometric detection of extended-spectrum beta-lactamase (ESBL) with carbon screen-printed sensors was investigated in the presence of the Nitrocefin, a commercially-available beta-lactamase chromogenic cephalosporin substrate. Carbon 75-81 EsbL Escherichia coli 30-62 25849107-1 2015 The amperometric detection of extended-spectrum beta-lactamase (ESBL) with carbon screen-printed sensors was investigated in the presence of the Nitrocefin, a commercially-available beta-lactamase chromogenic cephalosporin substrate. Carbon 75-81 EsbL Escherichia coli 64-68 25910448-0 2015 A novel antibody-antigen based impedimetric immunosensor for low level detection of HER2 in serum samples of breast cancer patients via modification of a gold nanoparticles decorated multiwall carbon nanotube-ionic liquid electrode. Carbon 193-199 erb-b2 receptor tyrosine kinase 2 Homo sapiens 84-88 25683967-2 2015 We determine that the equivalent mixture of a pair of alpha- and beta-galactolipids with a 14-carbon lipid chain can cause stronger poly ADP-ribose polymerase cleavage and DNA damage, producing more late apoptotic MM cells, than either anomer alone. Carbon 94-100 poly(ADP-ribose) polymerase 1 Homo sapiens 132-158 25910448-1 2015 A highly sensitive impedimetric immunosensor based on a gold nanoparticles/multiwall carbon nanotube-ionic liquid electrode (AuNPs/MW-CILE) was developed for the determination of human epidermal growth factor receptor 2 (HER2). Carbon 85-91 erb-b2 receptor tyrosine kinase 2 Homo sapiens 179-219 25784557-4 2015 Here, we demonstrate that Wnt activation promotes the phosphorylation of c-Cbl at tyrosine 731(Tyr-731), which increases c-Cbl dimerization and binding to beta-catenin. Carbon 31-32 catenin (cadherin-associated protein), beta 1 Danio rerio 155-167 25985465-6 2015 As a result, the N-doped 2D wavelike LTO with 0.6 wt.% of "carbon joint" not only exhibits exciting capacity of ~180 and ~150 mA h g(-1) for fast lithium storage at high discharge/charge rates of 1.7 and 8.5 A g(-1) (10C and 50C) respectively, but also shows excellent low-temperature performance at -20 C. In addition, the cost may be further decreased due to recycled functional reagents. Carbon 59-65 Rho GTPase activating protein 9 Homo sapiens 217-220 26504961-2 2015 In this work we showed that the use of functionalized multi-walled carbon nanotubes Nafion/MWCNTs composite film for modification of the carbon-based electrode surfaces would increase the charge transfer rate greatly; the composite has proven to efficiently immobilize two different heme proteins (catalase and cytochrome c) and to enhance the electrochemical performances of several carbon electrode materials (glassy carbon, mesoporous graphite, graphite and graphene) either used as classical electrodes or screen printed ones. Carbon 67-73 cytochrome c, somatic Homo sapiens 311-323 25950701-8 2015 Stimulation of LPMC with poly I:C but not PGN or CpG increased TNF-alpha and IFN-gamma in ILCs. Carbon 18-19 tumor necrosis factor Mus musculus 63-72 25950701-8 2015 Stimulation of LPMC with poly I:C but not PGN or CpG increased TNF-alpha and IFN-gamma in ILCs. Carbon 18-19 interferon gamma Mus musculus 77-86 25877886-6 2015 Regression analysis suggested that (1) nirK gene abundance was correlated with pile temperature following quadratic model; (2) nirS gene abundance was linearly correlated with pile temperature and concentration of NH4 (+), while correlated with concentration of NO3 (-) and pH following inverse and quadratic model respectively; (3) nosZ gene abundance was quadratically correlated with pH and linearly correlated with water soluble carbon (WSC). Carbon 433-439 NBL1, DAN family BMP antagonist Homo sapiens 262-265 29403633-3 2015 The potential susceptibility of Ni-S bonds in molecular hydrogen evolution catalysts to degradation via C-S bond cleavage is discussed. Carbon 104-105 solute carrier family 5 member 5 Homo sapiens 32-36 26415451-5 2015 And the carbon chain length of diesel is within the scope of C15 to C18. Carbon 8-14 Bardet-Biedl syndrome 9 Homo sapiens 68-71 25712164-3 2015 In this study, we used a RNA aptamer against EpCAM (EpDT3) attached physically to our newly synthesized non-viral vector, based on single-walled carbon nanotube (SWNT) conjugated to piperazine-polyethylenimine derivative. Carbon 145-151 epithelial cell adhesion molecule Homo sapiens 45-50 25846942-2 2015 An attractive methodology, single-electron transfer (SET) reductive cleavage of the C-S bond mediated by a metal in the presence of the external stimuli PPh3, has been applied to the kinetically inert IrCl3 in order to synthesize the thiolato complex [Ir(III)(L(S))Cl(PPh3)2] 3 from precursor thioether complexes [Ir(III)(L(SR))Cl2(PPh3)] (R = alkyl) 2. Carbon 84-85 caveolin 1 Homo sapiens 153-157 25846942-2 2015 An attractive methodology, single-electron transfer (SET) reductive cleavage of the C-S bond mediated by a metal in the presence of the external stimuli PPh3, has been applied to the kinetically inert IrCl3 in order to synthesize the thiolato complex [Ir(III)(L(S))Cl(PPh3)2] 3 from precursor thioether complexes [Ir(III)(L(SR))Cl2(PPh3)] (R = alkyl) 2. Carbon 84-85 caveolin 1 Homo sapiens 268-272 25846942-2 2015 An attractive methodology, single-electron transfer (SET) reductive cleavage of the C-S bond mediated by a metal in the presence of the external stimuli PPh3, has been applied to the kinetically inert IrCl3 in order to synthesize the thiolato complex [Ir(III)(L(S))Cl(PPh3)2] 3 from precursor thioether complexes [Ir(III)(L(SR))Cl2(PPh3)] (R = alkyl) 2. Carbon 84-85 caveolin 1 Homo sapiens 268-272 26504961-2 2015 In this work we showed that the use of functionalized multi-walled carbon nanotubes Nafion/MWCNTs composite film for modification of the carbon-based electrode surfaces would increase the charge transfer rate greatly; the composite has proven to efficiently immobilize two different heme proteins (catalase and cytochrome c) and to enhance the electrochemical performances of several carbon electrode materials (glassy carbon, mesoporous graphite, graphite and graphene) either used as classical electrodes or screen printed ones. Carbon 137-143 cytochrome c, somatic Homo sapiens 311-323 26504961-2 2015 In this work we showed that the use of functionalized multi-walled carbon nanotubes Nafion/MWCNTs composite film for modification of the carbon-based electrode surfaces would increase the charge transfer rate greatly; the composite has proven to efficiently immobilize two different heme proteins (catalase and cytochrome c) and to enhance the electrochemical performances of several carbon electrode materials (glassy carbon, mesoporous graphite, graphite and graphene) either used as classical electrodes or screen printed ones. Carbon 137-143 cytochrome c, somatic Homo sapiens 311-323 26504961-2 2015 In this work we showed that the use of functionalized multi-walled carbon nanotubes Nafion/MWCNTs composite film for modification of the carbon-based electrode surfaces would increase the charge transfer rate greatly; the composite has proven to efficiently immobilize two different heme proteins (catalase and cytochrome c) and to enhance the electrochemical performances of several carbon electrode materials (glassy carbon, mesoporous graphite, graphite and graphene) either used as classical electrodes or screen printed ones. Carbon 137-143 cytochrome c, somatic Homo sapiens 311-323 25858700-8 2015 We propose that both routes have been evolutionarily conserved in plants because, while PCK expends less energy, PPDK is twice as efficient at recovering carbon from pyruvate. Carbon 154-160 phosphoenolpyruvate carboxykinase 1 Arabidopsis thaliana 88-91 25736470-8 2015 Correspondingly, both photon and carbon ion irradiation downregulate soluble MMP9 concentrations, while upregulating cell surface expression of proadhesive extracellular matrix protein-binding integrin alpha5. Carbon 33-39 integrin subunit alpha 5 Homo sapiens 193-208 25736470-10 2015 Both photon and (even more so) carbon ion irradiation are effective in inhibiting medulloblastoma cell migration through downregulation of matrix metalloproteinase 9 and upregulation of proadhesive cell surface integrin alpha5, which lead to increased cell adherence to extracellular matrix proteins. Carbon 31-37 integrin subunit alpha 5 Homo sapiens 211-226 25944100-5 2015 atg12 plants have compromised autophagic transport as determined by localization of a YFP-ATG8 reporter and its vacuolar cleavage during nitrogen or fixed-carbon starvation. Carbon 155-161 Ubiquitin-like protein ATG12 Zea mays 0-5 25760981-10 2015 (-) from a carbon atom not involved in the pi conjugation system of the corrin occurs in the first step, resulting in formation of a Co(III) C-centered radical that undergoes rapid intramolecular electron transfer to form the corresponding Co(II) carbocation complex for about 50 % of these complexes. Carbon 11-17 mitochondrially encoded cytochrome c oxidase II Homo sapiens 133-138 25785370-0 2015 Orientation and density control of bispecific anti-HER2 antibody on functionalized carbon nanotubes for amplifying effective binding reactivity to cancer cells. Carbon 83-89 erb-b2 receptor tyrosine kinase 2 Homo sapiens 51-55 25785370-3 2015 Here, we describe a targeting nanomaterial platform utilizing carbon nanotubes functionalized with a cotinine-modified dextran polymer and a bispecific anti-HER2 x cotinine tandem antibody. Carbon 62-68 erb-b2 receptor tyrosine kinase 2 Homo sapiens 157-161 25785370-5 2015 The developed synthetic carbon nanotube/bispecific tandem antibody conjugates (denoted as SNAs) show an effective binding affinity against HER2 that is three orders of magnitude higher than that of the carbon nanotubes bearing a randomly conjugated tandem antibody prepared by carbodiimide chemistry. Carbon 24-30 erb-b2 receptor tyrosine kinase 2 Homo sapiens 139-143 32262329-7 2015 We also showed that C/Co@polyMAPTAC could reduce the cytotoxicity of the Abeta aggregate solutions. Carbon 20-21 amyloid beta precursor protein Homo sapiens 73-78 25858700-8 2015 We propose that both routes have been evolutionarily conserved in plants because, while PCK expends less energy, PPDK is twice as efficient at recovering carbon from pyruvate. Carbon 154-160 pyruvate orthophosphate dikinase Arabidopsis thaliana 113-117 25608933-6 2015 In this context, four types of NHC-complexes, i.e., carbon-functionalized NHCs, nitrogen-functionalized NHCs, oxygen-functionalized NHCs and nitrogen/oxygen-functionalized unsymmetric NHCs, are described. Carbon 52-58 high mobility group nucleosomal binding domain 4 Homo sapiens 31-34 25849210-1 2015 Ecologists have found a close relationship between the concentrations of nitrate (NO3-) and dissolved organic carbon (DOC) in ecosystems. Carbon 110-116 NBL1, DAN family BMP antagonist Homo sapiens 82-85 25577261-8 2015 It was accompanied by the normalization of the gene expression of BHMT, GNMT and MGAT, which code for key enzymes of one-carbon metabolism related to liver fat accumulation. Carbon 121-127 betaine-homocysteine S-methyltransferase Rattus norvegicus 66-70 25596325-0 2015 Specific aptamer-conjugated mesoporous silica-carbon nanoparticles for HER2-targeted chemo-photothermal combined therapy. Carbon 46-52 erb-b2 receptor tyrosine kinase 2 Homo sapiens 71-75 25596325-2 2015 In this work, a new HB5 aptamer-functionalized mesoporous silica-carbon based doxorubicin (DOX)-loaded system (MSCN-PEG-HB5/DOX) was successfully constructed and characterized for chemo-photothermal combined therapy of human epithelial growth factor receptor 2 (HER2)-positive breast cancer cells. Carbon 65-71 erb-b2 receptor tyrosine kinase 2 Homo sapiens 262-266 25670618-0 2015 Carbon ion beam triggers both caspase-dependent and caspase-independent pathway of apoptosis in HeLa and status of PARP-1 controls intensity of apoptosis. Carbon 0-6 poly(ADP-ribose) polymerase 1 Homo sapiens 115-121 25735540-4 2015 Here, we demonstrate that attaching an extremely long (~3 mum) and thin (~5 nm) tip by amorphous carbon to the cantilever allows us to image the surface structure of live cells with the spatiotemporal resolution of nanometers and seconds. Carbon 97-103 latexin Homo sapiens 58-61 25672970-5 2015 We demonstrated that C-30-27 selectively inhibited acetylation-dependent nuclear factor-kappaB (NF-kappaB) at Lys-122 and suppressed the NF-kappaB-mediated inflammatory response induced by lipopolysaccharide (LPS) or Abeta in both BV2 and Neuro-2A (N2A) cells. Carbon 21-22 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 73-94 25672970-5 2015 We demonstrated that C-30-27 selectively inhibited acetylation-dependent nuclear factor-kappaB (NF-kappaB) at Lys-122 and suppressed the NF-kappaB-mediated inflammatory response induced by lipopolysaccharide (LPS) or Abeta in both BV2 and Neuro-2A (N2A) cells. Carbon 21-22 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 96-105 25672970-5 2015 We demonstrated that C-30-27 selectively inhibited acetylation-dependent nuclear factor-kappaB (NF-kappaB) at Lys-122 and suppressed the NF-kappaB-mediated inflammatory response induced by lipopolysaccharide (LPS) or Abeta in both BV2 and Neuro-2A (N2A) cells. Carbon 21-22 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 137-146 25828701-6 2015 TRAF6 is determined to be a direct E3 ligase for GSK3beta, and TRAF6-mediated GSK3beta ubiquitination is essential for poly I:C-dependent cytokine production by promoting the TLR3 adaptor protein TRIF-assembled signalling complex. Carbon 126-127 TIR domain containing adaptor molecule 1 Homo sapiens 196-200 25748272-5 2015 We predominantly focus on recent findings that link select BCL-2 proteins to carbon substrate utilization at the level of mitochondrial fuel choice, electron transport, and metabolite import independent of their cell death regulatory function. Carbon 77-83 BCL2 apoptosis regulator Homo sapiens 59-64 25826744-4 2015 Over them, high carbon yield (96.7%) of C10 and C15 oxygenates was achieved. Carbon 16-22 homeobox C10 Homo sapiens 40-43 25679054-2 2015 Interestingly, resonance transitions observed in the C 1s region can be assigned to different carbon atoms in the molecule according to the degree of fluorine substitution. Carbon 94-100 complement C1s Homo sapiens 53-57 32262270-2 2015 Amino-functionalized multi-walled carbon nanotube (MWCNT-NH2) supported PdPt nanocages were used as catalytic labels of secondary anti-CEA. Carbon 34-40 CEA cell adhesion molecule 3 Homo sapiens 135-138 25736695-1 2015 Glycine decarboxylase (GLDC) acts in the glycine cleavage system to decarboxylate glycine and transfer a one-carbon unit into folate one-carbon metabolism. Carbon 109-115 glycine decarboxylase Mus musculus 0-21 25736695-1 2015 Glycine decarboxylase (GLDC) acts in the glycine cleavage system to decarboxylate glycine and transfer a one-carbon unit into folate one-carbon metabolism. Carbon 109-115 glycine decarboxylase Mus musculus 23-27 25736695-6 2015 In addition to elevated glycine, Gldc disruption also results in abnormal tissue folate profiles, with depletion of one-carbon-carrying folates, as well as growth retardation and reduced cellular proliferation. Carbon 120-126 glycine decarboxylase Mus musculus 33-37 25736695-7 2015 Formate treatment normalizes the folate profile, restores embryonic growth and prevents NTDs, suggesting that Gldc deficiency causes NTDs through limiting supply of one-carbon units from mitochondrial folate metabolism. Carbon 169-175 glycine decarboxylase Mus musculus 110-114 28756834-7 2015 Stability of PS 20 components was found to depend on the carbon number of polyethoxylated (POE) sorbitan FA ester and its order. Carbon 57-63 WAP four-disulfide core domain 1 Homo sapiens 13-18 25642736-0 2015 Carbon quantum dots-based recyclable real-time fluorescence assay for alkaline phosphatase with adenosine triphosphate as substrate. Carbon 0-6 alkaline phosphatase, placental Homo sapiens 70-90 25642736-1 2015 A convenient, reliable, and highly sensitive real-time assay for alkaline phosphatase (ALP) activity in the continuous and recyclable way is established on the basis of aggregation and disaggregation of carbon quantum dots (CQDs) through the competitive assay approach. Carbon 203-209 alkaline phosphatase, placental Homo sapiens 65-85 25642736-1 2015 A convenient, reliable, and highly sensitive real-time assay for alkaline phosphatase (ALP) activity in the continuous and recyclable way is established on the basis of aggregation and disaggregation of carbon quantum dots (CQDs) through the competitive assay approach. Carbon 203-209 alkaline phosphatase, placental Homo sapiens 87-90 25640477-8 2015 RESULTS: The mutant FLT3-ITD cells were more sensitive to C-1305 than the wild-type FLT3 and null-FLT3 cells (the IC50 values measured at 24 h were 1.2+-0.17, 2.0+-09, 7.6+-1.6 mumol/L, respectively). Carbon 58-59 fms related receptor tyrosine kinase 3 Homo sapiens 20-24 25640477-11 2015 Knockdown of FLT3 with siRNA significantly decreased C-1305-induced cytotoxicity in the mutant FLT3-ITD cells. Carbon 53-54 fms related receptor tyrosine kinase 3 Homo sapiens 13-17 25640477-11 2015 Knockdown of FLT3 with siRNA significantly decreased C-1305-induced cytotoxicity in the mutant FLT3-ITD cells. Carbon 53-54 fms related receptor tyrosine kinase 3 Homo sapiens 95-99 25599995-9 2015 Carboplatin and paclitaxel treatment combined with carbon-ion beams increased TUNEL-positive cells and the expression of cleaved caspase-3 and Bax, indicating the enhancement of apoptosis. Carbon 51-57 BCL2 associated X, apoptosis regulator Homo sapiens 143-146 25445478-1 2015 Capric acid (CA10) is a 10-carbon medium-chain fatty acid abundant in the medium-chain triglyceride ketogenic diet (MCT KD). Carbon 27-33 carbonic anhydrase 10 Mus musculus 13-17 25733650-12 2015 Expression changes in genes of one-carbon and lipid metabolism were particularly significant in FASD Mthfr(+/-) mice. Carbon 35-41 methylenetetrahydrofolate reductase Mus musculus 101-106 25241751-3 2015 In this laboratory study, a number of enhanced water treatment methods for DBP control, including enhanced coagulation, ozonation, and activated carbon adsorption, were evaluated for their effectiveness in treating SMP-containing water for the DBP reduction purpose. Carbon 145-151 D-box binding PAR bZIP transcription factor Homo sapiens 244-247 25241751-8 2015 In comparison, activated carbon adsorption is shown as a more effective means to remove the SMP content from water and hence to control the wastewater-derived DBP problem in water supply. Carbon 25-31 D-box binding PAR bZIP transcription factor Homo sapiens 159-162 24986777-2 2015 The anion anthraquinone-2-sulfonate (AQ) is used as an effective artificial electron transfer partner for NR at a glassy carbon (GC) electrode. Carbon 121-127 nitrate reductase 1 Arabidopsis thaliana 106-108 25581232-7 2015 Stability of PS 20 components was found to depend on the carbon number of polyethoxylated (POE) sorbitan FA ester and its order. Carbon 57-63 WAP four-disulfide core domain 1 Homo sapiens 13-18 25623286-1 2015 An azide (-N3) group attached at the -ortho carbon atom to the aniline moiety of 2-anilino-4,6-di-tert-butylphenol formed a diradical-containing Co(II) complex via inter-ligand azo (N=N) bond formation. Carbon 44-50 mitochondrially encoded cytochrome c oxidase II Homo sapiens 145-151 25648746-0 2015 Fog-like fluffy structured N-doped carbon with a superior oxygen reduction reaction performance to a commercial Pt/C catalyst. Carbon 35-41 zinc finger protein, FOG family member 1 Homo sapiens 0-3 25648746-1 2015 A high-performance N-doped carbon catalyst with a fog-like, fluffy structure was prepared through pyrolyzing a mixture of polyacrylonitrile, melamine and iron chloride. Carbon 27-33 zinc finger protein, FOG family member 1 Homo sapiens 50-53 25588737-3 2015 Tic56 mutant plants have an albino phenotype and are unable to grow without an external carbon source. Carbon 88-94 histone-lysine N-methyltransferase ATXR3-like protein Arabidopsis thaliana 0-5 25684275-1 2015 It is important to know the adsorption behavior and assembly structure of human serum albumin (HSA) molecules onto a carbonaceous substrate for further application of carbon nanomaterials in biomedical field. Carbon 117-123 albumin Homo sapiens 80-93 25684275-1 2015 It is important to know the adsorption behavior and assembly structure of human serum albumin (HSA) molecules onto a carbonaceous substrate for further application of carbon nanomaterials in biomedical field. Carbon 117-123 albumin Homo sapiens 95-98 25725705-2 2015 Exemplified by a series of crossed molecular beam studies on the reactions of a C-H stretch-excited CHD3(v1 = 1) with F, Cl, and O((3)P) atoms, two types of steric control of chemical reactivity will be highlighted. Carbon 80-81 chromodomain helicase DNA binding protein 3 Homo sapiens 100-104 25562342-1 2015 A practical sequence involving a noncryogenic stereospecific boronate rearrangement followed by a robust formylation with an in situ generated DCM anion has been developed for the asymmetric construction of an all-carbon quaternary stereogenic center of a FLAP inhibitor. Carbon 214-220 arachidonate 5-lipoxygenase activating protein Homo sapiens 256-260 25706562-1 2015 Arabidopsis ubiquitin ligases ATL31 and homologue ATL6 control the carbon/nitrogen nutrient and pathogen responses. Carbon 67-73 RING/U-box superfamily protein Arabidopsis thaliana 50-54 25240959-1 2015 We report a new electrochemical immunosensor for enhanced sensitive detection of human immunodeficiency virus p24 (HIV-p24) based on graphene oxide (GO) as a nanocarrier and enzyme encapsulated in carbon nanotubes-silica as a matrix in a multienzyme amplification strategy. Carbon 197-203 transmembrane p24 trafficking protein 2 Homo sapiens 110-113 25240959-1 2015 We report a new electrochemical immunosensor for enhanced sensitive detection of human immunodeficiency virus p24 (HIV-p24) based on graphene oxide (GO) as a nanocarrier and enzyme encapsulated in carbon nanotubes-silica as a matrix in a multienzyme amplification strategy. Carbon 197-203 transmembrane p24 trafficking protein 2 Homo sapiens 119-122 25240959-3 2015 After a sandwich immunoreactions, the HRP in carbon nanotubes-silica matrix and the HRP-HIV-p24-TH/GO captured onto the electrode surface produced an amplified electrocatalytic response by the reduction of enzymatically oxidized thionine in the presence of hydrogen peroxide. Carbon 45-51 transmembrane p24 trafficking protein 2 Homo sapiens 92-95 25584433-3 2015 Because membrane-bound TRAIL induces stronger receptor aggregation and apoptosis than soluble TRAIL, we proposed here to vectorize TRAIL using single-walled carbon nanotubes (SWCNTs) to mimic membrane TRAIL. Carbon 157-163 TNF superfamily member 10 Homo sapiens 23-28 25584433-0 2015 Nanovectorization of TRAIL with single wall carbon nanotubes enhances tumor cell killing. Carbon 44-50 TNF superfamily member 10 Homo sapiens 21-26 25428989-3 2015 The SNF1-dependent phosphorylation of Psk1 appears to be direct, in that Snf1 is necessary and sufficient for Psk1 activation by alternate carbon sources, is required for altered Psk1 protein mobility, is able to phosphorylate Psk1 in vitro, and binds Psk1 via its substrate-targeting subunit Gal83. Carbon 139-145 serine/threonine protein kinase PSK1 Saccharomyces cerevisiae S288C 38-42 25648319-0 2015 Multi-walled carbon nanotubes promote cementoblast differentiation and mineralization through the TGF-beta/Smad signaling pathway. Carbon 13-19 transforming growth factor beta 1 Homo sapiens 98-106 25648319-0 2015 Multi-walled carbon nanotubes promote cementoblast differentiation and mineralization through the TGF-beta/Smad signaling pathway. Carbon 13-19 SMAD family member 7 Homo sapiens 107-111 25648595-7 2015 We suggest that the propane molecule reacts when excited so that the CH3 group has been forced towards a flat structure with a carbon atom hybridization that is more sp2 than sp3. Carbon 127-133 Sp2 transcription factor Homo sapiens 166-169 25648595-7 2015 We suggest that the propane molecule reacts when excited so that the CH3 group has been forced towards a flat structure with a carbon atom hybridization that is more sp2 than sp3. Carbon 127-133 Sp3 transcription factor Homo sapiens 175-178 25523083-10 2015 This could account for the regulation of several carbon metabolism genes rather than DNA-repair genes under the regulation of LexA in cyanobacteria especially during high light induced oxidative stress. Carbon 49-55 DNA repair system Escherichia coli 126-130 26353609-2 2015 The results of these methods are found to be consistent with each other and evidence formation of chlorine-carbon groups and sp2 carbon shell on the nanodiamond surface. Carbon 129-135 Sp2 transcription factor Homo sapiens 125-128 25499653-3 2015 However, under the applied conditions (0.1-0.5% TFA in the mobile phase), it seemed that the main retention mechanism for proteins was hydrophobic interaction with the C18 alkylchains on this carbon based material. Carbon 192-198 Bardet-Biedl syndrome 9 Homo sapiens 168-171 25304811-10 2015 And ALDH1L1 involved in one carbon metabolism and CAPN1 participate in the apoptosis process by applying pathway analysis. Carbon 28-34 aldehyde dehydrogenase 1 family member L1 Homo sapiens 4-11 25562675-0 2015 Layer-by-layer assembled carbon nanotube-acetylcholinesterase/biopolymer renewable interfaces: SPR and electrochemical characterization. Carbon 25-31 acetylcholinesterase (Cartwright blood group) Homo sapiens 41-61 25562675-2 2015 We report a method for the renewal of layer-by-layer (LbL) self-assembled inhibition-based enzymatic interfaces in multiwalled carbon nanotube (MWCNT) armored acetylcholinesterase (AChE) biosensors. Carbon 127-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 159-179 25562675-2 2015 We report a method for the renewal of layer-by-layer (LbL) self-assembled inhibition-based enzymatic interfaces in multiwalled carbon nanotube (MWCNT) armored acetylcholinesterase (AChE) biosensors. Carbon 127-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 181-185 25562675-8 2015 In contrast, a similar LbL assembly of soluble enzyme/polyelectrolytes resulted in stronger desorption on the surface after the alkaline treatment; this led to the investigation of AChE layer removal, permanently inhibited after pesticide exposure on glassy carbon (GC) electrodes, while keeping the cushion layers intact. Carbon 258-264 acetylcholinesterase (Cartwright blood group) Homo sapiens 181-185 25743134-8 2015 Interesting reagents such as PARP and HSP90 inhibitors have been proposed as cancer cell- specific sensitizers for carbon-ion irradiation during basic biological studies, especially those from the Research Project with Heavy Ions at NIRS-HIMAC. Carbon 115-121 poly(ADP-ribose) polymerase 1 Homo sapiens 29-33 25428989-3 2015 The SNF1-dependent phosphorylation of Psk1 appears to be direct, in that Snf1 is necessary and sufficient for Psk1 activation by alternate carbon sources, is required for altered Psk1 protein mobility, is able to phosphorylate Psk1 in vitro, and binds Psk1 via its substrate-targeting subunit Gal83. Carbon 139-145 serine/threonine protein kinase PSK1 Saccharomyces cerevisiae S288C 110-114 25428989-3 2015 The SNF1-dependent phosphorylation of Psk1 appears to be direct, in that Snf1 is necessary and sufficient for Psk1 activation by alternate carbon sources, is required for altered Psk1 protein mobility, is able to phosphorylate Psk1 in vitro, and binds Psk1 via its substrate-targeting subunit Gal83. Carbon 139-145 serine/threonine protein kinase PSK1 Saccharomyces cerevisiae S288C 110-114 25428989-3 2015 The SNF1-dependent phosphorylation of Psk1 appears to be direct, in that Snf1 is necessary and sufficient for Psk1 activation by alternate carbon sources, is required for altered Psk1 protein mobility, is able to phosphorylate Psk1 in vitro, and binds Psk1 via its substrate-targeting subunit Gal83. Carbon 139-145 serine/threonine protein kinase PSK1 Saccharomyces cerevisiae S288C 110-114 25428989-3 2015 The SNF1-dependent phosphorylation of Psk1 appears to be direct, in that Snf1 is necessary and sufficient for Psk1 activation by alternate carbon sources, is required for altered Psk1 protein mobility, is able to phosphorylate Psk1 in vitro, and binds Psk1 via its substrate-targeting subunit Gal83. Carbon 139-145 serine/threonine protein kinase PSK1 Saccharomyces cerevisiae S288C 110-114 25146936-0 2015 The QQS orphan gene of Arabidopsis modulates carbon and nitrogen allocation in soybean. Carbon 45-51 qua-quine starch Arabidopsis thaliana 4-7 25146936-4 2015 Here, we show that altering QQS expression in Arabidopsis affects carbon partitioning to both starch and protein. Carbon 66-72 qua-quine starch Arabidopsis thaliana 28-31 25146936-8 2015 These data broaden the concept of QQS as a modulator of carbon and nitrogen allocation, and demonstrate that this species-specific gene can affect the seed composition of an agronomic species thought to have diverged from Arabidopsis 100 million years ago. Carbon 56-62 qua-quine starch Arabidopsis thaliana 34-37 25471346-3 2015 Transketolase (TK, EC 2.2.1.1) is a key enzyme in the photosynthetic carbon reduction cycle (Calvin cycle). Carbon 69-75 transketolase Cucumis sativus 0-13 25471346-3 2015 Transketolase (TK, EC 2.2.1.1) is a key enzyme in the photosynthetic carbon reduction cycle (Calvin cycle). Carbon 69-75 transketolase Cucumis sativus 15-17 26605048-7 2015 CONCLUSION: The present study first links PKS to biomineralization and provides a genetic cue for biogeochemistry of carbon and calcium cycles. Carbon 117-123 polyketide synthase 1 Oryzias latipes 42-45 25494307-1 2015 In this work, a sensitive electrochemical aptasensor for the detection of thrombin (TB) is developed and demonstrated based on the co-catalysis of hemin/G-quadruplex, platinum nanoparticles (PtNPs) and flower-like MnO2 nanosphere functionalized multi-walled carbon nanotubes (MWCNT-MnO2). Carbon 258-264 coagulation factor II, thrombin Homo sapiens 74-82 25494307-1 2015 In this work, a sensitive electrochemical aptasensor for the detection of thrombin (TB) is developed and demonstrated based on the co-catalysis of hemin/G-quadruplex, platinum nanoparticles (PtNPs) and flower-like MnO2 nanosphere functionalized multi-walled carbon nanotubes (MWCNT-MnO2). Carbon 258-264 coagulation factor II, thrombin Homo sapiens 84-86 25407563-5 2015 It was observed that in each case, a magnesium-carbon bond was inserted into the carbon-nitrogen double bond of either carbodiimides or Dipp2DAD resulting in a monoanionic amido-imino ligand. Carbon 47-53 nudix hydrolase 4 Homo sapiens 136-141 25407563-5 2015 It was observed that in each case, a magnesium-carbon bond was inserted into the carbon-nitrogen double bond of either carbodiimides or Dipp2DAD resulting in a monoanionic amido-imino ligand. Carbon 81-87 nudix hydrolase 4 Homo sapiens 136-141 25462862-7 2015 The carbon shell is effective in preventing the coalescence of L10-CoPt NPs during high temperature sintering. Carbon 4-10 immunoglobulin kappa variable 3-7 (non-functional) Homo sapiens 63-66 25542087-1 2015 An in-situ antimony film screen-printed carbon electrode (in-situ SbSPCE) was successfully used for the determination of Cu(II) simultaneously with Cd(II) and Pb(II) ions, by means of differential pulse anodic stripping voltammetry (DPASV), in a certified reference groundwater sample with a very high reproducibility and good trueness. Carbon 40-46 submaxillary gland androgen regulated protein 3B Homo sapiens 148-165 25407676-3 2015 We evaluate the adsorption behavior of small Abeta oligomers on the surface of a single walled carbon nanotube of high curvature. Carbon 95-101 amyloid beta precursor protein Homo sapiens 45-50 25548164-4 2015 MTHFD1 functions to condense formate with tetrahydrofolate and serves as the primary entry point of single carbons into folate-dependent one-carbon metabolism in the cytosol. Carbon 107-114 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 0-6 25548164-4 2015 MTHFD1 functions to condense formate with tetrahydrofolate and serves as the primary entry point of single carbons into folate-dependent one-carbon metabolism in the cytosol. Carbon 107-113 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens 0-6 25495051-6 2015 GRMZM2G393334 encodes a putative folylpolyglutamate synthase (FPGS), which functions in one-carbon (C1) metabolism to polyglutamylate substrates of folate-dependent enzymes. Carbon 92-98 folylpolyglutamate synthetase 1 Zea mays 0-13 25255886-0 2015 Multiwall carbon nanotubes directly promote fibroblast-myofibroblast and epithelial-mesenchymal transitions through the activation of the TGF-beta/Smad signaling pathway. Carbon 10-16 transforming growth factor beta 1 Homo sapiens 138-146 25365825-0 2015 In vitro HER2 protein-induced affinity dissociation of carbon nanotube-wrapped anti-HER2 aptamers for HER2 protein detection. Carbon 55-61 erb-b2 receptor tyrosine kinase 2 Homo sapiens 9-13 25365825-0 2015 In vitro HER2 protein-induced affinity dissociation of carbon nanotube-wrapped anti-HER2 aptamers for HER2 protein detection. Carbon 55-61 erb-b2 receptor tyrosine kinase 2 Homo sapiens 84-88 25365825-0 2015 In vitro HER2 protein-induced affinity dissociation of carbon nanotube-wrapped anti-HER2 aptamers for HER2 protein detection. Carbon 55-61 erb-b2 receptor tyrosine kinase 2 Homo sapiens 84-88 25365825-1 2015 A new in vitro assay was developed to detect human epidermal growth factor receptor 2 (HER2) protein, based on affinity dissociation of carbon nanotube (CNT)-wrapped anti-HER2 ssDNA aptamers. Carbon 136-142 erb-b2 receptor tyrosine kinase 2 Homo sapiens 51-85 25365825-1 2015 A new in vitro assay was developed to detect human epidermal growth factor receptor 2 (HER2) protein, based on affinity dissociation of carbon nanotube (CNT)-wrapped anti-HER2 ssDNA aptamers. Carbon 136-142 erb-b2 receptor tyrosine kinase 2 Homo sapiens 87-91 25365825-1 2015 A new in vitro assay was developed to detect human epidermal growth factor receptor 2 (HER2) protein, based on affinity dissociation of carbon nanotube (CNT)-wrapped anti-HER2 ssDNA aptamers. Carbon 136-142 erb-b2 receptor tyrosine kinase 2 Homo sapiens 171-175 26002730-5 2015 CYP-mediated hydroxylations occur via a consensus H atom abstraction/oxygen rebound mechanism involving an initial abstraction by CpdI of a H atom from the substrate, generating a highly-reactive protonated Compound II (CpdII) intermediate (FeIV-OH) and a carbon-centered alkyl radical that rebounds onto the ferryl hydroxyl moiety to yield the hydroxylated substrate. Carbon 256-262 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-3 25412253-4 2015 Confocal laser scanning microscopy visualized C-6 uptake into HCE-T cells in a time-resolved manner with an applied shear stress of 0.1 Pa. Static conditions were also studied for comparative purposes. Carbon 0-1 RNA guanylyltransferase and 5'-phosphatase Homo sapiens 62-65 26405999-3 2015 In this study, the characteristics of Abeta functional brain networks of Healthy Control (HC), Mild Cognitive Impairment (MCI), and AD groups were compared by applying graph theoretical analyses to Carbon 11-labeled Pittsburgh compound B positron emission tomography (11C PiB-PET) data. Carbon 198-204 amyloid beta precursor protein Homo sapiens 38-43 25344837-0 2015 Relationships among folate, alcohol consumption, gene variants in one-carbon metabolism and p16INK4a methylation and expression in healthy breast tissues. Carbon 70-76 cyclin dependent kinase inhibitor 2A Homo sapiens 92-100 26700591-3 2015 Here, we show that a branched-chain C-20 polyunsaturated fatty acid, geranylgeranoic acid (GGA), induces upregulation of the cellular protein levels of TP53-induced glycolysis and apoptosis regulator (TIGAR) and synthesis of cytochrome c oxidase 2 (SCO2) in human hepatoma-derived HuH-7cells harboring the mutant TP53 gene, suggesting that GGA may shift an energetic state of the tumor cells from aerobic glycolysis to mitochondrial respiration. Carbon 36-37 tumor protein p53 Homo sapiens 152-156 25355806-9 2015 Furthermore, TLR3 signalling pathway components, including NF-kappaB and IL-6/TNFalpha, were markedly upregulated upon stimulation with poly(I:C). Carbon 143-144 interleukin 6 Rattus norvegicus 73-77 25355806-9 2015 Furthermore, TLR3 signalling pathway components, including NF-kappaB and IL-6/TNFalpha, were markedly upregulated upon stimulation with poly(I:C). Carbon 143-144 tumor necrosis factor Rattus norvegicus 78-86 25344837-10 2015 Given that this is the first study to indicate that alcohol consumption, breast folate and variation in one-carbon metabolism genes are associated with p16(INK4a) promoter methylation and P16 protein expression in healthy tissues; these findings require replication. Carbon 108-114 cyclin dependent kinase inhibitor 2A Homo sapiens 152-155 25344837-10 2015 Given that this is the first study to indicate that alcohol consumption, breast folate and variation in one-carbon metabolism genes are associated with p16(INK4a) promoter methylation and P16 protein expression in healthy tissues; these findings require replication. Carbon 108-114 cyclin dependent kinase inhibitor 2A Homo sapiens 156-161 25344837-10 2015 Given that this is the first study to indicate that alcohol consumption, breast folate and variation in one-carbon metabolism genes are associated with p16(INK4a) promoter methylation and P16 protein expression in healthy tissues; these findings require replication. Carbon 108-114 cyclin dependent kinase inhibitor 2A Homo sapiens 188-191 25750456-3 2015 Mass Spectrometry (MS) has evolved as one of the most powerful tools in glycomics and glycoproteomics and in combination with porous graphitized carbon-liquid chromatography (PGC-LC) it is a versatile and sensitive technique for the analysis of glycans and to some extent also glycopeptides. Carbon 145-151 progastricsin Homo sapiens 175-178 25339220-0 2015 Template-directed in situ polymerization preparation of nanocomposites of PEDOT:PSS-coated multi-walled carbon nanotubes with enhanced thermoelectric property. Carbon 104-110 PSS Homo sapiens 80-83 25339220-1 2015 A template-directed in situ polymerization preparation of nanocomposites of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS)-coated multi-walled carbon nanotubes (MWCNTs) with greatly enhanced thermoelectric property is presented. Carbon 164-170 PSS Homo sapiens 139-142 25480007-0 2015 Response of nitrate reductase activity and NIA genes expression in roots of Arabidopsis hxk1 mutant treated with selected carbon and nitrogen metabolites. Carbon 122-128 nitrate reductase 1 Arabidopsis thaliana 12-29 28255396-12 2015 Conclusion:Our findings indicated hs-CRP levels of hemodialysis patients to have significant inverse relationships with serum albumin and vitamin E and C intakes but was not significant. Carbon 0-1 C-reactive protein Homo sapiens 37-40 25192468-1 2015 The effects of an eight-year natural aging of ASC impregnated activated carbon on the adsorption capacity and breakthrough times of model organic vapors and of the nerve agent sarin were investigated. Carbon 72-78 PYD and CARD domain containing Homo sapiens 46-49 25800844-4 2015 A combination of these two methods allows a precise and quantitative approach to interrogate the role of Rab25 as well as other Rab GTPases in central carbon energy metabolism. Carbon 151-157 RAB25, member RAS oncogene family Homo sapiens 105-110 25670360-7 2015 CO resulted in significantly larger least-squares mean % changes (all P < .001 vs EVOO) from baseline in LDL-C -10.9 vs -3.5, total-C -8.2 vs -1.8, non-HDL-C -9.3 vs -1.6, and total-C/HDL-C -4.4 vs 0.5. Carbon 0-1 component of oligomeric golgi complex 2 Homo sapiens 108-113 25754587-0 2015 Enhancement of cytotoxicity of artemisinin toward cancer cells by transferrin-mediated carbon nanotubes nanoparticles. Carbon 87-93 transferrin Homo sapiens 66-77 25697523-3 2015 We first outline the methods for large-scale production of stable, functional rhodopsin containing (13)C- and (15)N-labeled amino acids. Carbon 103-104 rhodopsin Homo sapiens 78-87 26339120-6 2015 Systemin promotes the expression of an array of defense genes that are dependent on different signaling pathways and it downregulates genes connected with carbon fixation and carbohydrate metabolism. Carbon 155-161 systemin Solanum lycopersicum 0-8 25461681-4 2015 In this study, we found that multiwalled carbon nanotubes (MWCNTs) reduced transport activity and expression of ABC transporters including ABCB1/Pgp and ABCC4/MRP4 in human colon adenocarcinoma Caco-2 cells. Carbon 41-47 ATP binding cassette subfamily B member 1 Homo sapiens 139-144 26368055-3 2015 On carbon or nitrogen starvation medium, atg5 colonies turned yellow earlier than the wild-type (WT) colonies, showing that Physcomitrella atg5 mutants, like yeast and Arabidopsis, are sensitive to nutrient starvation. Carbon 3-9 Atg5p Saccharomyces cerevisiae S288C 41-45 26368055-3 2015 On carbon or nitrogen starvation medium, atg5 colonies turned yellow earlier than the wild-type (WT) colonies, showing that Physcomitrella atg5 mutants, like yeast and Arabidopsis, are sensitive to nutrient starvation. Carbon 3-9 Atg5p Saccharomyces cerevisiae S288C 139-143 25281095-2 2015 The sorbent was obtained through the modification of carbon nanotubes (CNTs) with an external bovine serum albumin (BSA) layer, resulting in restricted access carbon nanotubes (RACNTs). Carbon 159-165 albumin Homo sapiens 101-114 25531293-0 2014 Carbon-ion beam irradiation kills X-ray-resistant p53-null cancer cells by inducing mitotic catastrophe. Carbon 0-6 tumor protein p53 Homo sapiens 50-53 26360759-0 2015 Removal of Pb(II) by adsorption onto Chinese walnut shell activated carbon. Carbon 68-74 submaxillary gland androgen regulated protein 3B Homo sapiens 11-17 26360759-3 2015 Chinese walnut shell activated carbon (CWSAC) was used as an adsorbent for the removal of Pb(II) from aqueous solution. Carbon 31-37 submaxillary gland androgen regulated protein 3B Homo sapiens 90-96 25367626-5 2014 Aziridinium-mediated carbon homologation of the hindered C-10 group to the homoallylic group facilitated the synthesis. Carbon 21-27 homeobox C10 Homo sapiens 57-61 25531293-1 2014 BACKGROUND AND PURPOSE: To understand the mechanisms involved in the strong killing effect of carbon-ion beam irradiation on cancer cells with TP53 tumor suppressor gene deficiencies. Carbon 94-100 tumor protein p53 Homo sapiens 143-147 25531293-4 2014 X-ray and carbon-ion beam irradiations predominantly induced apoptosis of the p53+/+ cells but not the p53-/- cells. Carbon 10-16 tumor protein p53 Homo sapiens 78-81 25531293-5 2014 In the p53-/- cells, carbon-ion beam irradiation, but not X-ray irradiation, markedly induced mitotic catastrophe that was associated with premature mitotic entry with harboring long-retained DSBs at 24 h post-irradiation. Carbon 21-27 tumor protein p53 Homo sapiens 7-10 25531293-6 2014 CONCLUSIONS: Efficient induction of mitotic catastrophe in apoptosis-resistant p53-deficient cells implies a strong cancer cell-killing effect of carbon-ion beam irradiation that is independent of the p53 status, suggesting its biological advantage over X-ray treatment. Carbon 146-152 tumor protein p53 Homo sapiens 79-82 25319968-3 2014 Using ab initio calculations and kinetic analyses, we disclose a specific type of carbon cluster, composed of a C21 core and a few dangling C atoms, which is exceptional stable in a size range from 21 to 27 C atoms. Carbon 82-88 TBL1X/Y related 1 Homo sapiens 112-115 25355315-3 2014 Transcription activation of both sets is regulated positively by the yeast AMP-activated protein kinase homolog, Snf1, in response to low glucose or the presence of a non-fermentable carbon source and negatively by two redundant 14-3-3 isoforms, Bmh1 and Bmh2. Carbon 183-189 14-3-3 family protein BMH1 Saccharomyces cerevisiae S288C 246-250 24973538-4 2014 When the material was immobilized on an ionic liquid functionalized graphene coated glassy carbon electrode for the electrochemical determination of fenitrothion, the resulting electrochemical sensor presented linear response in the range of 0.01-5 muM, with a sensitivity of 6.1 muA/muM mm(2). Carbon 91-97 latexin Homo sapiens 249-252 25319968-5 2014 The ultrastability of C21-3C originates from both the stable core and the appropriate passivation of the dangling carbon atoms by the catalyst surface. Carbon 114-120 TBL1X/Y related 1 Homo sapiens 22-25 26167268-1 2014 An enantioselective Cu(I)-catalyzed 1,3-halogen migration reaction accomplishes a formal hydrobromination by transferring a bromine activating group from a sp2 carbon to a benzylic carbon in good er and with concomitant borylation of the Ar-Br bond. Carbon 160-166 Sp2 transcription factor Homo sapiens 156-159 25493446-3 2014 The sp3-carbon atoms are photothermally converted to sp2-carbon atoms by pulsed laser irradiation. Carbon 8-14 Sp3 transcription factor Homo sapiens 4-7 25493446-3 2014 The sp3-carbon atoms are photothermally converted to sp2-carbon atoms by pulsed laser irradiation. Carbon 8-14 Sp2 transcription factor Homo sapiens 53-56 25493446-3 2014 The sp3-carbon atoms are photothermally converted to sp2-carbon atoms by pulsed laser irradiation. Carbon 57-63 Sp3 transcription factor Homo sapiens 4-7 25493446-3 2014 The sp3-carbon atoms are photothermally converted to sp2-carbon atoms by pulsed laser irradiation. Carbon 57-63 Sp2 transcription factor Homo sapiens 53-56 25479159-0 2014 Functional study of the Hap4-like genes suggests that the key regulators of carbon metabolism HAP4 and oxidative stress response YAP1 in yeast diverged from a common ancestor. Carbon 76-82 DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C 129-133 24930695-14 2014 Stimulation of microglia cells with supernatant of Poly I:C-treated RPE cells further elevated IL-6, IL-1ss and Cox2 expression, while it reduced the expression of iNOS. Carbon 58-59 nitric oxide synthase 2 Sus scrofa 164-168 25267444-2 2014 Prominent examples are the Schiff-base forming class I FBP and F6P aldolase as well as transaldolase, which all exploit an active center lysine to reversibly cleave the C3-C4 bond of fructose-1,6-bisphosphate or fructose-6-phosphate to give two 3-carbon products (aldolase), or to shuttle 3-carbon units between various phosphosugars (transaldolase). Carbon 247-253 ECB2 Homo sapiens 55-58 26167268-1 2014 An enantioselective Cu(I)-catalyzed 1,3-halogen migration reaction accomplishes a formal hydrobromination by transferring a bromine activating group from a sp2 carbon to a benzylic carbon in good er and with concomitant borylation of the Ar-Br bond. Carbon 181-187 Sp2 transcription factor Homo sapiens 156-159 25306271-9 2014 The AOX treatment increased the concentration and yield of 16-carbon milk FA, with no effect on de novo (<16 carbon) or preformed (>16 carbon) milk FA. Carbon 62-68 acyl-CoA oxidase 1 Bos taurus 4-7 25431418-1 2014 Glutamate decarboxylase (GAD) is an enzyme that catalyses the conversion of L-glutamate into gamma-aminobutyric acid (GABA), which is a four-carbon non-protein amino acid present in all organisms. Carbon 141-147 glutamate decarboxylase Glycine max 0-23 25431418-1 2014 Glutamate decarboxylase (GAD) is an enzyme that catalyses the conversion of L-glutamate into gamma-aminobutyric acid (GABA), which is a four-carbon non-protein amino acid present in all organisms. Carbon 141-147 glutamate decarboxylase Glycine max 25-28 24951924-0 2014 Preparation of magnetic TNT-imprinted polymer nanoparticles and their accumulation onto magnetic carbon paste electrode for TNT determination. Carbon 97-103 chromosome 16 open reading frame 82 Homo sapiens 24-27 25491822-0 2014 Application of CdO nanoparticle ionic liquid modified carbon paste electrode as a high sensitive biosensor for square wave voltammetric determination of NADH. Carbon 54-60 cell adhesion associated, oncogene regulated Homo sapiens 15-18 25491822-1 2014 In this paper we report the synthesis and application of CdO nanoparticle (CdO/NPs) and 1,3-dipropylimidazolium bromide as high sensitive sensors for voltammetric determination of nicotinamide adenine dinucleotide (NADH) using carbon paste electrode. Carbon 227-233 cell adhesion associated, oncogene regulated Homo sapiens 57-60 25491822-1 2014 In this paper we report the synthesis and application of CdO nanoparticle (CdO/NPs) and 1,3-dipropylimidazolium bromide as high sensitive sensors for voltammetric determination of nicotinamide adenine dinucleotide (NADH) using carbon paste electrode. Carbon 227-233 cell adhesion associated, oncogene regulated Homo sapiens 75-78 25491822-3 2014 Compared to common carbon paste electrode, the electrochemical response was greatly improved for NADH electrooxidation at a surface of CdO/NP modified ionic liquid carbon paste electrode (IL/CdO/NP/CPE). Carbon 19-25 cell adhesion associated, oncogene regulated Homo sapiens 135-138 25491822-3 2014 Compared to common carbon paste electrode, the electrochemical response was greatly improved for NADH electrooxidation at a surface of CdO/NP modified ionic liquid carbon paste electrode (IL/CdO/NP/CPE). Carbon 164-170 cell adhesion associated, oncogene regulated Homo sapiens 135-138 25491822-3 2014 Compared to common carbon paste electrode, the electrochemical response was greatly improved for NADH electrooxidation at a surface of CdO/NP modified ionic liquid carbon paste electrode (IL/CdO/NP/CPE). Carbon 164-170 cell adhesion associated, oncogene regulated Homo sapiens 191-194 25301888-4 2014 Both of the Arabidopsis (Arabidopsis thaliana) leaf-type FERREDOXIN-NADP(+) OXIDOREDUCTASE (FNR) isoforms, the key enzymes linking the light reactions of photosynthesis to carbon assimilation, exist as two distinct forms with different isoelectric points. Carbon 172-178 oxidoreductase Arabidopsis thaliana 76-90 25319360-1 2014 Magnesium-diboride-coated carbon nanotube arrays are synthesized by templating carbon-nanotube aerogel sheets with boron and then converting the boron to MgB2. Carbon 26-32 secretoglobin family 2A member 1 Homo sapiens 154-158 25553040-3 2014 Atoms attached to the pendent Csp (3)-S bond are arranged in a staggered conformation with one of the Cl atoms anti to the C atom in the aromatic ring [C-S-C-Cl torsion angles = 178.41 (11) and -176.70 (13) ]. Carbon 102-103 DnaJ heat shock protein family (Hsp40) member C5 Homo sapiens 30-33 25553040-3 2014 Atoms attached to the pendent Csp (3)-S bond are arranged in a staggered conformation with one of the Cl atoms anti to the C atom in the aromatic ring [C-S-C-Cl torsion angles = 178.41 (11) and -176.70 (13) ]. Carbon 102-103 DnaJ heat shock protein family (Hsp40) member C5 Homo sapiens 30-33 24967754-1 2014 Herein, we report a novel third-generation H2O2 and IO3- biosensor, which was fabricated by loading catalase (CAT) onto l-lysine/multiwalled carbon nanotube (PLL/f-MWCNT) film modified glassy carbon electrode (GCE). Carbon 141-147 catalase Homo sapiens 100-108 24967754-1 2014 Herein, we report a novel third-generation H2O2 and IO3- biosensor, which was fabricated by loading catalase (CAT) onto l-lysine/multiwalled carbon nanotube (PLL/f-MWCNT) film modified glassy carbon electrode (GCE). Carbon 141-147 catalase Homo sapiens 110-113 24967754-1 2014 Herein, we report a novel third-generation H2O2 and IO3- biosensor, which was fabricated by loading catalase (CAT) onto l-lysine/multiwalled carbon nanotube (PLL/f-MWCNT) film modified glassy carbon electrode (GCE). Carbon 192-198 catalase Homo sapiens 100-108 24967754-1 2014 Herein, we report a novel third-generation H2O2 and IO3- biosensor, which was fabricated by loading catalase (CAT) onto l-lysine/multiwalled carbon nanotube (PLL/f-MWCNT) film modified glassy carbon electrode (GCE). Carbon 192-198 catalase Homo sapiens 110-113 24951924-0 2014 Preparation of magnetic TNT-imprinted polymer nanoparticles and their accumulation onto magnetic carbon paste electrode for TNT determination. Carbon 97-103 chromosome 16 open reading frame 82 Homo sapiens 124-127 24951924-7 2014 It was found that the oxidative signal of TNT is much favorable for TNT detection on the resulting magnetic carbon paste electrode. Carbon 108-114 chromosome 16 open reading frame 82 Homo sapiens 42-45 24951924-7 2014 It was found that the oxidative signal of TNT is much favorable for TNT detection on the resulting magnetic carbon paste electrode. Carbon 108-114 chromosome 16 open reading frame 82 Homo sapiens 68-71 24967754-0 2014 A simple strategy for the immobilization of catalase on multi-walled carbon nanotube/poly (L-lysine) biocomposite for the detection of H2O2 and iodate. Carbon 69-75 catalase Homo sapiens 44-52 25225113-1 2014 An enantioselective copper-catalyzed asymmetric conjugate addition of Me2Zn to (Z)-nitroalkenes led to the formation of all-carbon quaternary stereogenic centers with high stereoselectivity. Carbon 124-130 malic enzyme 2 Homo sapiens 70-73 25365506-3 2014 In this work, we show that JEN1 mRNA accumulates in a dhh1 mutant, when formic acid was used as sole carbon source. Carbon 101-107 DExD/H-box ATP-dependent RNA helicase DHH1 Saccharomyces cerevisiae S288C 54-58 25365506-9 2014 Additionally, microarray analyses of dhh1 mutant indicated that Dhh1 plays a large role in metabolic adaptation, suggesting that carbon source changes triggers a complex interplay between transcriptional and post-transcriptional effects. Carbon 129-135 DExD/H-box ATP-dependent RNA helicase DHH1 Saccharomyces cerevisiae S288C 37-41 24737712-1 2014 Anacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has previously been shown to reduce low-density lipoprotein cholesterol (LDL-C) and raise high-density lipoprotein cholesterol (HDL-C) in patients with or at high risk of coronary heart disease in the 76-week, placebo-controlled, Determining the Efficacy and Tolerability of CETP Inhibition with Anacetrapib (DEFINE) trial. Carbon 150-152 cholesteryl ester transfer protein Homo sapiens 17-51 24942319-2 2014 To investigate the effects of carbon-ion irradiation on angiogenesis in lung cancer cells, we examined the expression of vascular endothelial growth factor and basic fibroblast growth factor in the tumor conditioned medium (TCM) of A549 cells exposed to carbon-ion or X-ray irradiation, as well as endothelial cell growth, invasion, and tube formation induced by TCM. Carbon 254-260 vascular endothelial growth factor A Homo sapiens 121-155 24942319-6 2014 These findings suggest that carbon-ion irradiation at 1 Gy significantly suppressed the process of angiogenesis in vitro by inhibiting endothelial cell invasion and tube formation, which are related to vascular endothelial growth factor and basic fibroblast growth factor production. Carbon 28-34 vascular endothelial growth factor A Homo sapiens 202-236 24737712-1 2014 Anacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has previously been shown to reduce low-density lipoprotein cholesterol (LDL-C) and raise high-density lipoprotein cholesterol (HDL-C) in patients with or at high risk of coronary heart disease in the 76-week, placebo-controlled, Determining the Efficacy and Tolerability of CETP Inhibition with Anacetrapib (DEFINE) trial. Carbon 150-152 cholesteryl ester transfer protein Homo sapiens 53-57 25356552-2 2014 In Saccharomyces cerevisiae, growth in non-preferred carbon sources (like galactose) induces differentiation to the filamentous cell type through an extracellular-signal regulated kinase (ERK)-type MAPK pathway. Carbon 53-59 mitogen-activated protein kinase 1 Homo sapiens 188-191 25069063-4 2014 Geochemical modelling therefore identifies waters towards the centre of the Grand Erg Oriental basin as palaeowaters in line with reported (14)C and (36)Cl ages. Carbon 143-144 ETS transcription factor ERG Homo sapiens 82-85 25019650-8 2014 Insulin-resistant individuals had higher mean age (p=0.000), body mass index (BMI; p=0.000), abdominal circumference (p=0.000), median triglycerides (p=0.001), total cholesterol (p<=0.042), and low-density lipoprotein cholesterol (LDL-C; p<=0.027); and lower HDL-C levels (p=0.005). Carbon 237-239 insulin Homo sapiens 0-7 25726671-1 2014 A diagnostic reagent application based on carbon nanoparticles covalently functionalized by streptococcus G-protein was investigated in order to construct a system for the monitoring and optimization of the affinity purification technology of rabbit polyclonal antibodies to alpha-fetoprotein. Carbon 42-48 alpha fetoprotein Homo sapiens 275-292 25458692-2 2014 With the aid of ultrasonication, melamine-formaldehyde-tetraoxalyl-ethylenediamine chelating resins were grafted on activated carbon (MFT/AC). Carbon 126-132 solute carrier family 25 member 32 Homo sapiens 134-137 25898638-3 2014 Through analyzing the data of forest inventory and the generalized allometric equations between volume and biomass, previous studies had reported that biomass carbon storage of the forests in Inner Mongolia was about 920 Tg C, which was 12 percent of the national forest carbon storage, the annual average growth rate was about 1.4%, and the average of carbon density was about 43 t hm(-2). Carbon 159-165 transglutaminase 2 Homo sapiens 221-225 25356552-2 2014 In Saccharomyces cerevisiae, growth in non-preferred carbon sources (like galactose) induces differentiation to the filamentous cell type through an extracellular-signal regulated kinase (ERK)-type MAPK pathway. Carbon 53-59 mitogen-activated protein kinase 1 Homo sapiens 198-202 25337902-11 2014 Heterogeneity across alcohol consumption status of the associations between MTR/MTRR polymorphisms and these cancers indicates potential interactions between alcohol drinking and one-carbon metabolic pathway. Carbon 183-189 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 80-84 25251502-1 2014 Engineered nanomaterials (ENMs) including multiwall carbon nanotubes (MWCNTs) and rare earth oxide (REO) nanoparticles, which are capable of activating the NLRP3 inflammasome and inducing IL-1beta production, have the potential to cause chronic lung toxicity. Carbon 52-58 NLR family pyrin domain containing 3 Homo sapiens 156-161 25252141-1 2014 Aromatase is the cytochrome P450 enzyme that cleaves the C10-C19 carbon-carbon bond of androgens to form estrogens, in a three-step process. Carbon 65-71 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 0-9 25252141-1 2014 Aromatase is the cytochrome P450 enzyme that cleaves the C10-C19 carbon-carbon bond of androgens to form estrogens, in a three-step process. Carbon 72-78 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 0-9 25298227-2 2014 Mechanistic studies suggest a single catalyst, derived from Pd(dba)2 and NiXantPhos, efficiently catalyzes alpha-arylation of sulfides, C-S bond cleavage, and C-S bond formation in a tricatalytic cycle. Carbon 136-137 DBA2 Homo sapiens 60-68 25307742-6 2014 We document a similar pattern in the early phases of diet-induced insulin resistance, and propose that FoxOs are required to enable the liver to direct nutritionally derived carbons to glucose versus lipid metabolism. Carbon 174-181 insulin Homo sapiens 66-73 25392786-0 2014 Carbon nanodots interference with lactate dehydrogenase assay in human monocyte THP-1 cells. Carbon 0-6 GLI family zinc finger 2 Homo sapiens 80-85 25392786-8 2014 FINDINGS: This study investigated the possible interference of carbon nanodots on the LDH assay in human monocyte THP-1 cells. Carbon 63-69 GLI family zinc finger 2 Homo sapiens 114-119 25111796-8 2014 The Au-H bond is relatively weak but, for interactions via an H atom that is bonded to a carbon atom (e.g., CH4), we find that there is large charge polarization of the Au-H-C moiety and partial activation of the inert C-H bond. Carbon 89-95 AU RNA binding methylglutaconyl-CoA hydratase Homo sapiens 4-8 25111796-8 2014 The Au-H bond is relatively weak but, for interactions via an H atom that is bonded to a carbon atom (e.g., CH4), we find that there is large charge polarization of the Au-H-C moiety and partial activation of the inert C-H bond. Carbon 89-95 AU RNA binding methylglutaconyl-CoA hydratase Homo sapiens 169-173 25111796-8 2014 The Au-H bond is relatively weak but, for interactions via an H atom that is bonded to a carbon atom (e.g., CH4), we find that there is large charge polarization of the Au-H-C moiety and partial activation of the inert C-H bond. Carbon 108-109 AU RNA binding methylglutaconyl-CoA hydratase Homo sapiens 4-8 25111796-8 2014 The Au-H bond is relatively weak but, for interactions via an H atom that is bonded to a carbon atom (e.g., CH4), we find that there is large charge polarization of the Au-H-C moiety and partial activation of the inert C-H bond. Carbon 108-109 AU RNA binding methylglutaconyl-CoA hydratase Homo sapiens 169-173 25111796-8 2014 The Au-H bond is relatively weak but, for interactions via an H atom that is bonded to a carbon atom (e.g., CH4), we find that there is large charge polarization of the Au-H-C moiety and partial activation of the inert C-H bond. Carbon 174-175 AU RNA binding methylglutaconyl-CoA hydratase Homo sapiens 4-8 25111796-8 2014 The Au-H bond is relatively weak but, for interactions via an H atom that is bonded to a carbon atom (e.g., CH4), we find that there is large charge polarization of the Au-H-C moiety and partial activation of the inert C-H bond. Carbon 174-175 AU RNA binding methylglutaconyl-CoA hydratase Homo sapiens 169-173 25160825-4 2014 One-pot electrophilic substitution of the C(sp2)-Zn bond by Cu(I)-mediated C-C bond formation and subsequent manipulation of the C(sp2)-Si bond provides a modular access to Z-alpha,beta-disubstituted enamides. Carbon 42-43 Sp2 transcription factor Homo sapiens 129-134 25160825-4 2014 One-pot electrophilic substitution of the C(sp2)-Zn bond by Cu(I)-mediated C-C bond formation and subsequent manipulation of the C(sp2)-Si bond provides a modular access to Z-alpha,beta-disubstituted enamides. Carbon 60-61 Sp2 transcription factor Homo sapiens 42-47 25160825-4 2014 One-pot electrophilic substitution of the C(sp2)-Zn bond by Cu(I)-mediated C-C bond formation and subsequent manipulation of the C(sp2)-Si bond provides a modular access to Z-alpha,beta-disubstituted enamides. Carbon 60-61 Sp2 transcription factor Homo sapiens 129-134 25688502-12 2014 After irradiation with carbon ions and temozolomide, cell survival rates depended on p53 status, with a decreased survival rate in wildtype cells. Carbon 23-29 tumor protein p53 Homo sapiens 85-88 25157877-5 2014 From the computed reaction free energy profiles it follows that the most likely mechanism of 4-hydroxyphenylpyruvate dioxygenase involves electrophilic attack on the C1 carbon of the ring and subsequent single-step heterolytic migration of the substituent. Carbon 169-175 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 93-128 25100852-7 2014 The PCP domain was shown to have deubiquitinase activity for both RIG-I and TBK-1, whose ubiquitination is a key step in their activation in poly(I C)-induced IFN induction. Carbon 5-6 interferon alpha 1 Homo sapiens 159-162 25222611-2 2014 Herein, an electrochemical platform for the investigation of drug metabolism in vitro was constructed by immobilizing cytochrome P450 2D6 (CYP2D6) with cyt P450 reductase (CPR) on graphene modified glass carbon electrode. Carbon 204-210 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 118-137 25222611-2 2014 Herein, an electrochemical platform for the investigation of drug metabolism in vitro was constructed by immobilizing cytochrome P450 2D6 (CYP2D6) with cyt P450 reductase (CPR) on graphene modified glass carbon electrode. Carbon 204-210 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 139-145 25222611-2 2014 Herein, an electrochemical platform for the investigation of drug metabolism in vitro was constructed by immobilizing cytochrome P450 2D6 (CYP2D6) with cyt P450 reductase (CPR) on graphene modified glass carbon electrode. Carbon 204-210 cytochrome p450 oxidoreductase Homo sapiens 172-175 24879591-1 2014 We report a protein antibody, Ab-CRP, functionalized Pt nanoparticle-decorated chemical vapor deposition (CVD)-grown graphene on glassy carbon electrode, as a bioelectrode, for the quantitative analysis of human C-reactive protein (CRP). Carbon 136-142 C-reactive protein Homo sapiens 33-36 25059158-7 2014 The calculated result shows that the amounts of conjugated C-16 and C-18 on 1mg of NPs (9.2 pmol) are about 13.5 pmol and 15.5 pmol, respectively. Carbon 59-60 Bardet-Biedl syndrome 9 Homo sapiens 68-72 25100546-3 2014 In the presence of PPh3, a formal [2+2+1+1] cycloaddition reaction proceeds to afford regioisomeric phenylacetic acids via cleavage of the C=C bond. Carbon 139-140 caveolin 1 Homo sapiens 19-23 25100546-3 2014 In the presence of PPh3, a formal [2+2+1+1] cycloaddition reaction proceeds to afford regioisomeric phenylacetic acids via cleavage of the C=C bond. Carbon 141-142 caveolin 1 Homo sapiens 19-23 24105920-1 2014 In continuation of the research on the thermally induced chemical transformation of the silica-based chemically bonded stationary phases (C18), the oxidative cleavage of the silicon-carbon bonds with hydrogen peroxide and potassium fluoride was utilized, followed by the gas chromatography coupled with mass spectrometry (GC-MS) study of the resulting products. Carbon 182-188 Bardet-Biedl syndrome 9 Homo sapiens 138-141 24176765-1 2014 Research over the last decade has revealed that CYP11A1 can hydroxylate the side chain of vitamin D3 at carbons 17, 20, 22 and 23 to produce at least 10 metabolites, with 20(OH)D3, 20,23(OH)2D3, 20,22(OH)2D3, 17,20(OH)2D3 and 17,20,23(OH)3D3 being the main products. Carbon 104-111 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 48-55 25281689-2 2014 We have recently discovered ATG8-INTERACTING PROTEIN1 (ATI1) from Arabidopsis thaliana and showed that following carbon starvation it is localized on endoplasmic reticulum (ER)-associated bodies that are subsequently transported to the vacuole. Carbon 113-119 mesoderm induction early response protein Arabidopsis thaliana 28-53 25281689-2 2014 We have recently discovered ATG8-INTERACTING PROTEIN1 (ATI1) from Arabidopsis thaliana and showed that following carbon starvation it is localized on endoplasmic reticulum (ER)-associated bodies that are subsequently transported to the vacuole. Carbon 113-119 mesoderm induction early response protein Arabidopsis thaliana 55-59 25281689-3 2014 Here, we show that following carbon starvation ATI1 is also located on bodies associating with plastids, which are distinct from the ER ATI bodies and are detected mainly in senescing cells that exhibit plastid degradation. Carbon 29-35 mesoderm induction early response protein Arabidopsis thaliana 47-51 25181346-0 2014 High-temperature calcined fullerene nanowhiskers as well as long needle-like multi-wall carbon nanotubes have abilities to induce NLRP3-mediated IL-1beta secretion. Carbon 88-94 NLR family pyrin domain containing 3 Homo sapiens 130-135 25181346-0 2014 High-temperature calcined fullerene nanowhiskers as well as long needle-like multi-wall carbon nanotubes have abilities to induce NLRP3-mediated IL-1beta secretion. Carbon 88-94 interleukin 1 beta Homo sapiens 145-153 25181346-5 2014 IL-1beta release induced by long-HTCFNW as well as by long, needle-like MWCNTs was abolished by a caspase-1 inhibitor or siRNA-knockdown of NLRP3, indicating that NLRP3-inflammasome-mediated IL-1beta production by these carbon nanofibers. Carbon 220-226 interleukin 1 beta Homo sapiens 0-8 25181346-5 2014 IL-1beta release induced by long-HTCFNW as well as by long, needle-like MWCNTs was abolished by a caspase-1 inhibitor or siRNA-knockdown of NLRP3, indicating that NLRP3-inflammasome-mediated IL-1beta production by these carbon nanofibers. Carbon 220-226 NLR family pyrin domain containing 3 Homo sapiens 140-145 25181346-5 2014 IL-1beta release induced by long-HTCFNW as well as by long, needle-like MWCNTs was abolished by a caspase-1 inhibitor or siRNA-knockdown of NLRP3, indicating that NLRP3-inflammasome-mediated IL-1beta production by these carbon nanofibers. Carbon 220-226 NLR family pyrin domain containing 3 Homo sapiens 163-168 25057851-3 2014 The amphiphilic carbon dots enabled imaging of membrane disruption by the beta-amyloid peptide. Carbon 16-22 amyloid beta precursor protein Homo sapiens 74-94 24709327-0 2014 Label-free detection of C-reactive protein using a carbon nanofiber based biosensor. Carbon 51-57 C-reactive protein Homo sapiens 24-42 24709327-1 2014 We report the sensitive detection of C-reactive protein (CRP), a biomarker for cardiac disease, using a carbon nanofiber based biosensor platform. Carbon 104-110 C-reactive protein Homo sapiens 37-55 24709327-1 2014 We report the sensitive detection of C-reactive protein (CRP), a biomarker for cardiac disease, using a carbon nanofiber based biosensor platform. Carbon 104-110 C-reactive protein Homo sapiens 57-60 25122922-5 2014 PL-C also synergized with IL-12, even at the low cytokine concentration of 0.1 ng/ml, and stimulated IFN-gamma production in both human CD56(bright) and CD56(dim) NK cell subsets. Carbon 3-4 interferon gamma Homo sapiens 101-110 25136739-4 2014 The conversion was prevented by migration of a C-C bond within the geometrically stressed C10 framework. Carbon 47-48 homeobox C10 Homo sapiens 90-93 25136739-4 2014 The conversion was prevented by migration of a C-C bond within the geometrically stressed C10 framework. Carbon 49-50 homeobox C10 Homo sapiens 90-93 25229628-7 2014 The potential carbon sequestration of forest ecosystems was 77.3 Tg C if all forested lands were restored to natural tropical forests. Carbon 14-20 transglutaminase 2 Homo sapiens 65-69 24994664-0 2014 Carbon nanotube wiring for signal amplification of electrochemical magneto immunosensors: application to myeloperoxidase detection. Carbon 0-6 myeloperoxidase Homo sapiens 105-120 25188266-5 2014 We also found that one-carbon metabolism (OCM) impairment plays a significant role in alcohol toxicity to the PFC seen from the difference in the effects of acute and chronic alcohol exposure on DNA repair and from exaggeration of the damaging effects upon additional OCM impairment in mice deficient in a key OCM enzyme, methylenetetrahydrofolate reductase (MTHFR). Carbon 23-29 methylenetetrahydrofolate reductase Mus musculus 322-357 25188266-5 2014 We also found that one-carbon metabolism (OCM) impairment plays a significant role in alcohol toxicity to the PFC seen from the difference in the effects of acute and chronic alcohol exposure on DNA repair and from exaggeration of the damaging effects upon additional OCM impairment in mice deficient in a key OCM enzyme, methylenetetrahydrofolate reductase (MTHFR). Carbon 23-29 methylenetetrahydrofolate reductase Mus musculus 359-364 32262199-2 2014 Here, we report the modulation of enzyme (porcine pancreatic lipase, PPL) catalytic activity in the presence of carbon quantum dots (CQDs) by visible light. Carbon 112-118 periplakin Homo sapiens 69-72 25156066-3 2014 Computational analyses showed that the reduction of pi conjugation in substituted five-membered rings plays a major role, while the reduced bond angles, in addition to the strengthened induction of Csp(2) versus Csp(3), further favor the deprotonation of endocyclic carbon sites rather than that of the methyl group. Carbon 266-272 regulator of calcineurin 2 Homo sapiens 198-203 24994664-1 2014 In this work, chronoamperometric myelo-peroxidase (MPO) detection was accomplished using immunofunctionalized magnetic microparticles (MPs), disposable carbon screen-printed electrodes (C-SPEs), and a ready-to-use commercially available tetramethylbenzidine (TMB)-based enzymatic substrate. Carbon 152-158 myeloperoxidase Homo sapiens 33-49 24994664-1 2014 In this work, chronoamperometric myelo-peroxidase (MPO) detection was accomplished using immunofunctionalized magnetic microparticles (MPs), disposable carbon screen-printed electrodes (C-SPEs), and a ready-to-use commercially available tetramethylbenzidine (TMB)-based enzymatic substrate. Carbon 152-158 myeloperoxidase Homo sapiens 51-54 24967976-1 2014 We report the effects of carbon concentration on the microstructures and tensile deformation behaviors of thermomechanically processed Ni-free Co-29Cr-9W-1Si-C (mass%) alloys designed for use as disk materials in CAD/CAM dental technology. Carbon 25-31 calmodulin 3 Homo sapiens 217-220 24641999-2 2014 This study aimed to investigate whether Dalesconol B (TL-2), a potent immunosuppressive agent with an unusual carbon skeleton, could inhibit Abeta-induced apoptosis in vitro and in vivo and to explore the underlying mechanisms. Carbon 110-116 brachyury, T-box transcription factor T Mus musculus 54-58 25083590-8 2014 Porous carbon submicrospheres were obtained after the removal of RE2O3 and REN from the composite spheres. Carbon 7-13 renin Homo sapiens 75-78 25019574-0 2014 Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation. Carbon 118-124 ras homolog family member A Homo sapiens 98-102 24992071-6 2014 Herein, we report on the development of a new class of cationic lipid-Dex conjugates in which the C-8 carbon chain analogue (DX8) exhibited glucocorticoid receptor (GR)-mediated, caspase-3-assisted, cancer cell-selective anti-proliferative activity. Carbon 102-108 nuclear receptor subfamily 3, group C, member 1 Mus musculus 140-163 24992071-6 2014 Herein, we report on the development of a new class of cationic lipid-Dex conjugates in which the C-8 carbon chain analogue (DX8) exhibited glucocorticoid receptor (GR)-mediated, caspase-3-assisted, cancer cell-selective anti-proliferative activity. Carbon 102-108 nuclear receptor subfamily 3, group C, member 1 Mus musculus 165-167 25080102-1 2014 With the help of mixed ligand catalytic systems, the analogous mechanisms behind the cognate performance by Pd(dba)2 and Pd2(dba)3 in catalyzing C-N and C-S coupling reactions were demonstrated. Carbon 145-146 DBA2 Homo sapiens 108-116 25001594-2 2014 We describe in this work a novel electrochemical immunosensor design making use of carbon nanohorns (CNHs) as a scaffold for the preparation of disposable immunosensing platforms for the determination of fibrinogen (Fib). Carbon 83-89 fibrinogen beta chain Homo sapiens 204-214 24924949-4 2014 For saturated aldehydes the optimum chain length for inhibition of 2E1 was 9 carbons (KI=7.8 +- 0.3 muM), whereas for 2A6 heptanal was most potent (KI=15.8 +- 1.1 muM). Carbon 77-84 latexin Homo sapiens 100-103 25068977-2 2014 Composite particles of polyzwitterion coated carbon nanotubes (SBMA@CNT) are prepared via a precipitation polymerization method. Carbon 45-51 androgen receptor Homo sapiens 63-67 25010336-4 2014 Interestingly, it was found that the CTAB bilayer confined at the interface of carbon dots can amplify H2O2 induced ultraweak CL emissions, such as the Co(II)-triggered Fenton-like reaction, the peroxynitrous acid (ONOOH) system, and the peroxymonocarbonate (HCO4(-)) system. Carbon 79-85 mitochondrially encoded cytochrome c oxidase II Homo sapiens 152-157 25001594-2 2014 We describe in this work a novel electrochemical immunosensor design making use of carbon nanohorns (CNHs) as a scaffold for the preparation of disposable immunosensing platforms for the determination of fibrinogen (Fib). Carbon 83-89 fibrinogen beta chain Homo sapiens 216-219 25001594-3 2014 The approach involved the immobilization of Fib onto activated CNHs deposited on screen-printed carbon electrodes (SPCEs) and the implementation of an indirect competitive assay using anti-Fib labeled with horseradish peroxidase (HRP) and hydroquinone (HQ) as the redox mediator. Carbon 96-102 fibrinogen beta chain Homo sapiens 44-47 24865983-7 2014 Interestingly, octanoate-derived carbon labeled glucose uniquely in livers of PPARalpha-KO neonates. Carbon 33-39 peroxisome proliferator activated receptor alpha Mus musculus 78-87 25064241-1 2014 An amperometric immunoassay for the determination of tumor necrosis factor alpha (TNFalpha) protein biomarker in human serum based on the use of magnetic microbeads (MBs) and disposable screen-printed carbon electrodes (SPCEs) has been developed. Carbon 201-207 tumor necrosis factor Homo sapiens 82-90 25338399-3 2014 The influence of Pb(II) concentration, adsorption time on Pb(II) adsorption on the ethanediamine-modified mesoporous carbon (AC-EDA) was investigated. Carbon 117-123 submaxillary gland androgen regulated protein 3B Homo sapiens 58-64 25338399-6 2014 The adsorption amount of Pb(II) on the carbon increased with the increase of solution pH in acidic conditions. Carbon 39-45 submaxillary gland androgen regulated protein 3B Homo sapiens 25-31 22905667-0 2014 Histometric changes and epidermal FGF9 expression in carbon photoenhancer-assisted Nd:YAG laser treatment. Carbon 53-59 fibroblast growth factor 9 Mus musculus 34-38 22905667-7 2014 Earlier and more pronounced expression of FGF9 was detected in mice treated with carbon photoenhancer-assisted quasi-long pulsed laser therapy. Carbon 81-87 fibroblast growth factor 9 Mus musculus 42-46 22905667-8 2014 In addition, two peaks of pronounced FGF9 expression were observed, especially in mice that underwent carbon photoenhancer-assisted 1064-nm quasi-long pulsed Nd:YAG laser treatment. Carbon 102-108 fibroblast growth factor 9 Mus musculus 37-41 24996063-1 2014 Covalent Si-C grafting of a silatrane cage to a carbon-based interface provides a truly conjugated benzyl-type system in which the 3 c-4 e orbital of the silatrane interacts with the macroscopic pi-type substituent (graphite Csp2 network) through hyperconjugation. Carbon 48-54 regulator of calcineurin 2 Homo sapiens 225-229 24753029-6 2014 Losses of forest cover and Other Wooded Land (OWL) cover result in estimates of carbon losses which are similar for 1990s and 2000s at 887 MtC yr(-1) (range: 646-1238) and 880 MtC yr(-1) (range: 602-1237) respectively, with humid regions contributing two-thirds. Carbon 80-86 metallothionein 1A Homo sapiens 176-179 24753029-12 2014 Our estimates of annual removals of carbon from forest regrowth at 115 MtC yr(-1) (range: 61-168) and 97 MtC yr(-1) (53-141) for the 1990s and 2000s respectively are five to fifteen times lower than earlier published estimates. Carbon 36-42 metallothionein 1A Homo sapiens 71-74 24753029-12 2014 Our estimates of annual removals of carbon from forest regrowth at 115 MtC yr(-1) (range: 61-168) and 97 MtC yr(-1) (53-141) for the 1990s and 2000s respectively are five to fifteen times lower than earlier published estimates. Carbon 36-42 metallothionein 1A Homo sapiens 105-108 24673477-9 2014 KEY FINDINGS: 3-(aminoalkyl)-5-fluoroindole derivative with 5 carbons on the side chain and paroxetine showed the best activity on both MPO and SERT at the nanomolar range. Carbon 62-69 myeloperoxidase Homo sapiens 136-139 24673477-9 2014 KEY FINDINGS: 3-(aminoalkyl)-5-fluoroindole derivative with 5 carbons on the side chain and paroxetine showed the best activity on both MPO and SERT at the nanomolar range. Carbon 62-69 solute carrier family 6 member 4 Homo sapiens 144-148 24996063-1 2014 Covalent Si-C grafting of a silatrane cage to a carbon-based interface provides a truly conjugated benzyl-type system in which the 3 c-4 e orbital of the silatrane interacts with the macroscopic pi-type substituent (graphite Csp2 network) through hyperconjugation. Carbon 0-1 regulator of calcineurin 2 Homo sapiens 225-229 24981175-4 2014 Akt phosphorylates TKT on Thr382, markedly enhancing enzyme activity and increasing carbon flow through the nonoxidative PPP, thereby increasing purine synthesis. Carbon 84-90 AKT serine/threonine kinase 1 Homo sapiens 0-3 24981175-4 2014 Akt phosphorylates TKT on Thr382, markedly enhancing enzyme activity and increasing carbon flow through the nonoxidative PPP, thereby increasing purine synthesis. Carbon 84-90 transketolase Homo sapiens 19-22 32261741-3 2014 Proposed interactions relevant to the stabilisation of the final oligonucleotide-CNP complex include pi-pi stacking and pi-HN bonding with sp2 carbon atoms on the CNP surface. Carbon 143-149 Sp2 transcription factor Homo sapiens 139-142 24709520-1 2014 Multiwalled carbon nanotubes (MWCNTs) are cut short and grafted with polyethylenimine (PEI) for further covalent conjugation to fluorescein isothiocyanate (FITC) and prostate stem cell antigen (PSCA) monoclonal antibody (mAb). Carbon 12-18 prostate stem cell antigen Mus musculus 194-198 24974868-0 2014 DNA impedance biosensor for detection of cancer, TP53 gene mutation, based on gold nanoparticles/aligned carbon nanotubes modified electrode. Carbon 105-111 tumor protein p53 Homo sapiens 49-53 24974868-1 2014 For the first time, a new platform based on electrochemical growth of Au nanoparticles on aligned multi-walled carbon nanotubes (A-MWCNT) was developed for sensitive lable-free DNA detection of the TP53 gene mutation, one of the most popular genes in cancer research. Carbon 111-117 tumor protein p53 Homo sapiens 198-202 24363178-4 2014 Mitochondrial pyruvate metabolism is regulated by many enzymes, including the recently discovered mitochondria pyruvate carrier, pyruvate dehydrogenase, and pyruvate carboxylase, to modulate overall pyruvate carbon flux. Carbon 208-214 pyruvate carboxylase Homo sapiens 157-177 24825369-8 2014 At adolescence, offspring exposed prenatally to poly I:C had significantly lower CB1R relative Standard Uptake Values (rSUV) compared to controls in the globus pallidus (p=0.046). Carbon 55-56 cannabinoid receptor 1 Homo sapiens 81-85 24814977-9 2014 Treatment of mouse AML12 hepatocytes with the PPARbeta agonist (GW0742) decreased (14)C-18:2,n-6 in TGs but did not affect beta-oxidation. Carbon 86-87 peroxisome proliferator activator receptor delta Mus musculus 46-54 24731006-6 2014 The ability of carbon ions to inhibit the activation of the PI3K/Akt pathway rose with increasing their LET. Carbon 15-21 AKT serine/threonine kinase 1 Homo sapiens 65-68 24825369-9 2014 In adulthood, however, poly I:C exposed offspring had higher levels of CB1R rSUV in sensory cortex (p=0.034) and hypothalamus (p=0.032) compared to controls. Carbon 30-31 cannabinoid receptor 1 Homo sapiens 71-75 25016257-5 2014 (1) The 1H-NMR signals at ~5.5, 4-8, 7.4-10.2, and 12.22-12.37 ppm were attributed to the chemical shifts of active protons on carbons adjacent to R-OH, RAr-OH, oximes, and -COOH, respectively. Carbon 127-134 RAB40B, member RAS oncogene family Homo sapiens 153-156 24844815-2 2014 Plants over-expressing ACL were generated in an effort to understand the contribution of ACL activity to the carbon flux of acetyl-CoA to metabolic pathways occurring in the cytosol. Carbon 109-115 acetone-cyanohydrin lyase Arabidopsis thaliana 23-26 24844815-2 2014 Plants over-expressing ACL were generated in an effort to understand the contribution of ACL activity to the carbon flux of acetyl-CoA to metabolic pathways occurring in the cytosol. Carbon 109-115 acetone-cyanohydrin lyase Arabidopsis thaliana 89-92 24844815-8 2014 Together, these results reveal the complexity of ACL regulation and its central role in influencing the carbon flux to metabolic pathways using cytosolic acetyl-CoA, including wax and polyisoprenoids. Carbon 104-110 acetone-cyanohydrin lyase Arabidopsis thaliana 49-52 24763966-4 2014 The embedded 1 mm glassy carbon electrode had a limit of detection (LOD) of 500 nM for dopamine and a linear response (R(2) = 0.99) for concentrations between 25-500 muM. Carbon 25-31 latexin Homo sapiens 166-169 24995502-7 2014 Myeloperoxidase release was inhibited by urolithins A and C (at 20 microM by 46.7 +- 16.1 and 63.8 +- 8.6%, respectively). Carbon 58-59 myeloperoxidase Homo sapiens 0-15 24582468-1 2014 Light-dependent de novo volatile isoprene emission by terrestrial plants (approximately 2% of carbon fixed during photosynthesis) contributes as much as 0.5 PgC/year to the global carbon cycle. Carbon 180-186 progastricsin Homo sapiens 157-160 24962398-0 2014 Three-dimensional heterocycles: new uracil-based structures obtained by nucleophilic substitution at the sp2 carbon of bromoisoxazoline. Carbon 109-115 Sp2 transcription factor Homo sapiens 105-108 24962398-2 2014 The key-synthetic step is the nucleophilic substitution at the sp2 carbon atom of the bromoisoxazoline three-dimensional heterocycles. Carbon 67-73 Sp2 transcription factor Homo sapiens 63-66 24870066-0 2014 Binding of human serum albumin to single-walled carbon nanotubes activated neutrophils to increase production of hypochlorous acid, the oxidant capable of degrading nanotubes. Carbon 48-54 albumin Homo sapiens 17-30 24817487-1 2014 We present the first in silico modeling of the Pd-H-single-walled carbon nanohorn nanocomposites. Carbon 66-72 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 47-51 24820873-0 2014 The Abeta peptide forms non-amyloid fibrils in the presence of carbon nanotubes. Carbon 63-69 amyloid beta precursor protein Homo sapiens 4-9 24820873-3 2014 Here, we used NMR, CD, and ThT/fluorescence spectroscopy together with AFM imaging to study pH-dependent molecular interactions between single walled carbon nanotubes (SWNTs) and the amyloid-beta (Abeta) peptide. Carbon 150-156 amyloid beta precursor protein Homo sapiens 197-202 24870066-1 2014 Previous studies have shown that carboxylated single-walled carbon nanotubes (SWCNTs) can be catalytically biodegraded by hypochlorite (OCl-) and reactive radical intermediates of the human neutrophil enzyme myeloperoxidase (MPO). Carbon 60-66 myeloperoxidase Homo sapiens 225-228 24870066-7 2014 Our findings suggest that the binding of HSA may be an important determinant for MPO-mediated SWCNT biodegradation in human inflammatory cells and therefore shed light on the biomedical and biotechnological applications of safe carbon nanotubes by comprehensive preconsideration of their interactions with human serum proteins. Carbon 228-234 myeloperoxidase Homo sapiens 81-84 24939878-0 2014 Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis. Carbon 82-88 caveolin 1 Homo sapiens 0-10 24939878-0 2014 Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis. Carbon 82-88 tumor protein p53 Homo sapiens 62-65 24798487-4 2014 In this method, p-nitroaniline (pNA) released from Asp-Glu-Val-Asp-pNA by caspase-3 enzyme reaction was measured with DPV by using a glassy carbon electrode. Carbon 140-146 caspase 3 Homo sapiens 74-83 24971065-0 2014 Role of H-Ras/ERK signaling in carbon nanotube-induced neoplastic-like transformation of human mesothelial cells. Carbon 31-37 mitogen-activated protein kinase 3 Homo sapiens 14-17 24905485-2 2014 Both compounds possess an unprecedented bicyclo [10.3.1] ring system with C-C bond connections between C-10 and C-20, and between C-20 and C-11. Carbon 74-75 homeobox C10 Homo sapiens 103-107 24905485-2 2014 Both compounds possess an unprecedented bicyclo [10.3.1] ring system with C-C bond connections between C-10 and C-20, and between C-20 and C-11. Carbon 76-77 homeobox C10 Homo sapiens 103-107 24905485-2 2014 Both compounds possess an unprecedented bicyclo [10.3.1] ring system with C-C bond connections between C-10 and C-20, and between C-20 and C-11. Carbon 76-77 homeobox C10 Homo sapiens 103-107 24893038-0 2014 Carbon ion radiation inhibits glioma and endothelial cell migration induced by secreted VEGF. Carbon 0-6 vascular endothelial growth factor A Homo sapiens 88-92 24893038-4 2014 However, glioma cells treated with conditioned medium of cells irradiated at a carbon ion dose of 4.0 Gy showed a marked decrease in migratory potential and VEGF secretion relative to non-irradiated cells. Carbon 79-85 vascular endothelial growth factor A Homo sapiens 157-161 24893038-5 2014 The application of recombinant VEGF165 stimulated migration in glioma and endothelial cells, which was associated with increased FAK phosphorylation at Tyr861, suggesting that the suppression of cell migration by carbon ion radiation could be via VEGF-activated FAK signaling. Carbon 213-219 vascular endothelial growth factor A Homo sapiens 31-35 24893038-6 2014 Taken together, these findings indicate that carbon ion may be superior to X-ray radiation for inhibiting tumorigenesis and angiogenesis through modulation of VEGF level in the glioma microenvironment. Carbon 45-51 vascular endothelial growth factor A Homo sapiens 159-163 24771656-1 2014 The synthesis of Spi(tau-dec), derived from the selective alkylation of L-spinacine (4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid) at the tau-nitrogen of its heteroaromatic ring, with a linear hydrocarbon chain of 10 carbon atoms, is described here for the first time. Carbon 216-222 chromogranin A Homo sapiens 17-20 24666478-4 2014 We find that self-implanted carbon under the implantation conditions used for the material investigated in this paper creates an amorphous region with significant sp 2 content that varies across the interface. Carbon 28-34 Sp2 transcription factor Homo sapiens 163-167 24770487-1 2014 LDL-cholesterol (LDL-C) uptake by Ldlr is regulated at the transcriptional level by the cleavage-dependent activation of membrane-associated sterol response element-binding protein (SREBP-2). Carbon 21-22 sterol regulatory element binding transcription factor 2 Homo sapiens 182-189 24835107-4 2014 Continuing studies based on measurements of the nuclear spin relaxation rates running via the SC2 mechanism (scalar relaxation of the second kind), we present in this work the results obtained for three molecules: 9-bromotriptycene, 1,3,5-tribromobenzene, and 1-(2-bromoethynyl)-4-ethynylbenzene in which C-Br bond and one of C-H bonds are collinear. Carbon 0-1 trans-2,3-enoyl-CoA reductase Homo sapiens 94-97 24835107-5 2014 Separation of saturation-recovery or inversion-recovery curves of (13)C NMR signals of bromine-bonded carbons in the investigated compounds on two components has provided the longitudinal SC2 relaxation rates of these carbons in (79)Br- and (81)Br-containing isotopomers. Carbon 102-109 trans-2,3-enoyl-CoA reductase Homo sapiens 188-191 24835107-5 2014 Separation of saturation-recovery or inversion-recovery curves of (13)C NMR signals of bromine-bonded carbons in the investigated compounds on two components has provided the longitudinal SC2 relaxation rates of these carbons in (79)Br- and (81)Br-containing isotopomers. Carbon 218-225 trans-2,3-enoyl-CoA reductase Homo sapiens 188-191 26580767-3 2014 These alkanolamines are derivatives of MEA obtained by substitution with methyl and ethyl groups on the carbon atoms of the N-C-C-O backbone. Carbon 104-110 male-enhanced antigen 1 Homo sapiens 39-42 26580767-3 2014 These alkanolamines are derivatives of MEA obtained by substitution with methyl and ethyl groups on the carbon atoms of the N-C-C-O backbone. Carbon 126-127 male-enhanced antigen 1 Homo sapiens 39-42 26580767-3 2014 These alkanolamines are derivatives of MEA obtained by substitution with methyl and ethyl groups on the carbon atoms of the N-C-C-O backbone. Carbon 128-129 male-enhanced antigen 1 Homo sapiens 39-42 24673155-4 2014 Insulin degludec is a desB30 insulin acylated at the LysB29 residue with a glutamate linker and 16-carbon fatty diacyl side chain. Carbon 99-105 insulin Homo sapiens 0-7 24673155-4 2014 Insulin degludec is a desB30 insulin acylated at the LysB29 residue with a glutamate linker and 16-carbon fatty diacyl side chain. Carbon 99-105 insulin Homo sapiens 29-36 25158483-4 2014 The stable isotopic compositions of dissolved inorganic carbon (delta13C(DIC)) indicated that DIC in the Guijiang River had been assimilated by the phytoplankton in photosynthesis. Carbon 56-62 solute carrier family 25 member 10 Homo sapiens 94-97 25158483-5 2014 The primary production of phytoplankton contributed to 22.3%-30.9% of particulate organic carbon (POC) in the Guijiang River, which implies that phytoplankton can transform DIC into POC by photosynthesis, and parts of POC will sink into the bottom of the river in transit, which leads into the formation of burial organic carbon. Carbon 90-96 solute carrier family 25 member 10 Homo sapiens 173-176 25158483-5 2014 The primary production of phytoplankton contributed to 22.3%-30.9% of particulate organic carbon (POC) in the Guijiang River, which implies that phytoplankton can transform DIC into POC by photosynthesis, and parts of POC will sink into the bottom of the river in transit, which leads into the formation of burial organic carbon. Carbon 322-328 solute carrier family 25 member 10 Homo sapiens 173-176 23776096-8 2014 The results suggest that the optimal roughness parameters for MG 63 cell on carbon based surface were Ra ~ 3.5 microm, RSm ~0.03-0.08 mm, Rsk ~0 or negative and Rku ~ 20, DLC being the best material choice. Carbon 76-82 ribosomal protein S6 kinase A2 Homo sapiens 138-141 24560951-2 2014 Anti-human epidermal growth factor receptor antibody was covalently immobilized onto a screen-printed carbon electrode modified with a carbon nanotube. Carbon 102-108 epidermal growth factor receptor Homo sapiens 11-43 24668066-2 2014 In this study, a porous graphitized carbon (PGC) absorbent was combined with a C18 adsorbent for N-glycopeptide purification in comprehensive N-glycoproteome analysis based on the hydrophobic and polar interactions between carbon and N-glycans. Carbon 223-229 Bardet-Biedl syndrome 9 Homo sapiens 79-82 24668066-3 2014 It was observed that the small hydrophilic N-glycopeptides that cannot retain onto C18 adsorbent can be captured by the graphitized carbon, while the large hydrophobic N-glycopeptides that cannot retain onto the graphitized carbon can be feasibly captured by the C18 adsorbent. Carbon 132-138 Bardet-Biedl syndrome 9 Homo sapiens 83-86 24668066-3 2014 It was observed that the small hydrophilic N-glycopeptides that cannot retain onto C18 adsorbent can be captured by the graphitized carbon, while the large hydrophobic N-glycopeptides that cannot retain onto the graphitized carbon can be feasibly captured by the C18 adsorbent. Carbon 132-138 Bardet-Biedl syndrome 9 Homo sapiens 263-266 23636593-4 2014 Recent biodegradation studies in Africa have revealed the existence of exotic bacterial strains exhibiting unique and unusual PCB metabolic capability in terms of array of congeners that can serve as carbon source and diversity of congeners attacked, marking considerable progress in the development of effective bioremediation strategies for PCB-contaminated matrices such as sediments and soils in tropical regions. Carbon 200-206 pyruvate carboxylase Homo sapiens 126-129 23636593-4 2014 Recent biodegradation studies in Africa have revealed the existence of exotic bacterial strains exhibiting unique and unusual PCB metabolic capability in terms of array of congeners that can serve as carbon source and diversity of congeners attacked, marking considerable progress in the development of effective bioremediation strategies for PCB-contaminated matrices such as sediments and soils in tropical regions. Carbon 200-206 pyruvate carboxylase Homo sapiens 343-346 24706893-6 2014 In addition, under carbon starvation, the HSP31 family gene-deletion strains display impaired autophagy, disrupted target of rapamycin complex 1 (TORC1) localization to P-bodies, and caused abnormal TORC1-mediated Atg13 phosphorylation. Carbon 19-25 glutathione-independent methylglyoxalase Saccharomyces cerevisiae S288C 42-47 24731819-2 2014 Acetylcholinesterase (AChE) was immobilized onto a glassy carbon electrode (GCE) with the aid of Cu-Mg-Al calcined layered double hydroxide (CLDH). Carbon 58-64 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 24731819-2 2014 Acetylcholinesterase (AChE) was immobilized onto a glassy carbon electrode (GCE) with the aid of Cu-Mg-Al calcined layered double hydroxide (CLDH). Carbon 58-64 acetylcholinesterase (Cartwright blood group) Homo sapiens 22-26 28788640-10 2014 The kinetics data for Ni(II), Pb(II) and Cr(VI) by the best selected activated carbon fitted very well to the pseudo-second-order kinetic model. Carbon 79-85 submaxillary gland androgen regulated protein 3B Homo sapiens 30-36 24584631-1 2014 Carbon-carbon bond cleavage reactions are catalyzed by, among others, lanosterol 14-demethylase (CYP51), cholesterol side-chain cleavage enzyme (CYP11), sterol 17beta-lyase (CYP17), and aromatase (CYP19). Carbon 0-6 cytochrome P450 family 51 subfamily A member 1 Homo sapiens 97-102 24584631-1 2014 Carbon-carbon bond cleavage reactions are catalyzed by, among others, lanosterol 14-demethylase (CYP51), cholesterol side-chain cleavage enzyme (CYP11), sterol 17beta-lyase (CYP17), and aromatase (CYP19). Carbon 0-6 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 197-202 24584631-1 2014 Carbon-carbon bond cleavage reactions are catalyzed by, among others, lanosterol 14-demethylase (CYP51), cholesterol side-chain cleavage enzyme (CYP11), sterol 17beta-lyase (CYP17), and aromatase (CYP19). Carbon 7-13 cytochrome P450 family 51 subfamily A member 1 Homo sapiens 97-102 24584631-1 2014 Carbon-carbon bond cleavage reactions are catalyzed by, among others, lanosterol 14-demethylase (CYP51), cholesterol side-chain cleavage enzyme (CYP11), sterol 17beta-lyase (CYP17), and aromatase (CYP19). Carbon 7-13 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 197-202 24560951-2 2014 Anti-human epidermal growth factor receptor antibody was covalently immobilized onto a screen-printed carbon electrode modified with a carbon nanotube. Carbon 135-141 epidermal growth factor receptor Homo sapiens 11-43 24616245-0 2014 Spectroscopic investigations on the interaction between carbon nanotubes and catalase on molecular level. Carbon 56-62 catalase Homo sapiens 77-85 24616245-1 2014 The interactions between well-dispersed multiwalled carbon nanotubes (MWCNTs) and catalase (CAT) were investigated. Carbon 52-58 catalase Homo sapiens 82-90 24616245-1 2014 The interactions between well-dispersed multiwalled carbon nanotubes (MWCNTs) and catalase (CAT) were investigated. Carbon 52-58 catalase Homo sapiens 92-95 24534637-11 2014 Activated carbon is the most effective solution as it reduced the chlorine dioxide consumption by about 50% and the DBP formation by about 20-40%. Carbon 10-16 D-box binding PAR bZIP transcription factor Homo sapiens 116-119 24594037-1 2014 Carbon nanotubes-mesostructured silica nanoparticles (CNT-MSN) composites were prepared by a simple one step method with various loading of CNT. Carbon 0-6 moesin Homo sapiens 58-61 24812999-8 2014 These results show that at 0-20 cm layer, 58.9 tonnes of carbon ha-1 was measured under species-poor pastureland and 106.1 tonnes of carbon ha under species-rich vegetation. Carbon 57-63 Rho GTPase activating protein 45 Homo sapiens 64-68 24608564-6 2014 The activities of both enzymes were determined after culturing at 37 C at pH 6.0 for 30 h. The optimal production of alpha- and beta-galactosidases was obtained with soybean oligosaccharides as a carbon source and proteose peptone no. Carbon 196-202 alpha galactosidase Glycine max 117-147 24720974-0 2014 A competitive electrochemical immunosensor for the detection of human interleukin-6 based on the electrically heated carbon electrode and silver nanoparticles functionalized labels. Carbon 117-123 interleukin 6 Homo sapiens 70-83 24492533-2 2014 In this work, the reactions of C-H bond activation by two series of iron-oxo ( (Fe(IV)), (Fe(V)), (Fe(VI))) and -nitrido model complexes ( (Fe(IV)), (Fe(V)), (Fe(VI))) with a nearly identical coordination geometry but varying iron oxidation states ranging from iv to vi were comprehensively investigated using density functional theory. Carbon 31-32 FEV transcription factor, ETS family member Homo sapiens 89-95 24565804-8 2014 Relatively higher intensity of diverse multi-heme cytochrome c (putatively involved in electrons transfer) and carbon fixation genes was observed in the biocarbonate-fed biocathode, likely met the requirement of the energy conservation and maintained the nitrobenzene selective reduction capability after carbon source switchover. Carbon 156-162 cytochrome c, somatic Homo sapiens 50-62 24492533-2 2014 In this work, the reactions of C-H bond activation by two series of iron-oxo ( (Fe(IV)), (Fe(V)), (Fe(VI))) and -nitrido model complexes ( (Fe(IV)), (Fe(V)), (Fe(VI))) with a nearly identical coordination geometry but varying iron oxidation states ranging from iv to vi were comprehensively investigated using density functional theory. Carbon 31-32 FEV transcription factor, ETS family member Homo sapiens 149-155 24508894-0 2014 New insight into the binding interaction of hydroxylated carbon nanotubes with bovine serum albumin. Carbon 57-63 albumin Homo sapiens 86-99 24736561-0 2014 Chemical control of electrical contact to sp2 carbon atoms. Carbon 46-52 Sp2 transcription factor Homo sapiens 42-45 24679098-5 2014 A careful separation of saturation-recovery curves, measured for signals of (13)C nuclei at 7.05 and 11.7 T on two components, has provided the longitudinal SC2 relaxation rates of carbon signals in (79)Br and (81)Br containing isotopomers of the investigated compounds. Carbon 181-187 trans-2,3-enoyl-CoA reductase Homo sapiens 157-160 24758421-11 2014 Over-expression of OSM1, on the other hand, led to a diversion of carbon from glycerol to acetate and a decrease in growth rate by 39% in defined medium and by 25% in complex medium. Carbon 66-72 fumarate reductase Saccharomyces cerevisiae S288C 19-23 24758421-12 2014 Combined over-expression of OSM1 and ERO1 led to the same diversion of carbon from glycerol to acetate and had a stronger detrimental effect on the growth in complex medium. Carbon 71-77 fumarate reductase Saccharomyces cerevisiae S288C 28-32 24758421-12 2014 Combined over-expression of OSM1 and ERO1 led to the same diversion of carbon from glycerol to acetate and had a stronger detrimental effect on the growth in complex medium. Carbon 71-77 ER oxidoreductin Saccharomyces cerevisiae S288C 37-41 24577225-0 2014 N-Heterocyclic carbene-catalyzed formal cross-coupling reaction of alpha-haloenals with thiols: organocatalytic construction of sp2 carbon-sulfur bonds. Carbon 132-138 Sp2 transcription factor Homo sapiens 128-131 24700524-2 2014 Our computational exploration of their corresponding potential-energy surfaces at the S12h/TZ2P level shows that indeed stable carbon-free inverse-sandwiches can be obtained if one chooses an appropriate Group 13 element for E. The boron analogue B2P4 does not form the D(4h)-symmetric inverse-sandwich structure, but instead prefers a D(2d) structure of two perpendicular BP2 units with the formation of a double B-B bond. Carbon 127-133 BP2 Homo sapiens 373-376 24530588-6 2014 Significant correlations were observed between total organic carbon (TOC) contents and PCB concentrations in the soils. Carbon 61-67 pyruvate carboxylase Homo sapiens 87-90 24503195-0 2014 Multiwall carbon nanotube-ionic liquid electrode modified with gold nanoparticles as a base for preparation of a novel impedimetric immunosensor for low level detection of human serum albumin in biological fluids. Carbon 10-16 albumin Homo sapiens 178-191 24561005-10 2014 Taken together, CYP2E1 metabolism may be modified in vivo by exposure to 4-carbon compounds, such as drugs, and nutritional constituents, a finding that highlights the complexity of exposure to mixtures. Carbon 75-81 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 16-22 24370115-1 2014 An Interleukin-6 (IL-6) electrochemical immunosensor was fabricated based on the Au nanoparticles (AuNP)-graphene-silica sol-gel as immobilization biointerface and AuNP-polydopamine (PDA)@carbon nanotubes (CNT) as the label of HRP-bound antibodies. Carbon 188-194 interleukin 6 Homo sapiens 3-16 24370115-1 2014 An Interleukin-6 (IL-6) electrochemical immunosensor was fabricated based on the Au nanoparticles (AuNP)-graphene-silica sol-gel as immobilization biointerface and AuNP-polydopamine (PDA)@carbon nanotubes (CNT) as the label of HRP-bound antibodies. Carbon 188-194 interleukin 6 Homo sapiens 18-22 24569140-6 2014 ELOVL4 elongated appropriate precursors to the corresponding VLC-FA species >= 28 carbons. Carbon 85-92 ELOVL fatty acid elongase 4 Homo sapiens 0-6 24729658-0 2014 Mechanistic Imperatives for Deprotonation of Carbon Catalyzed by Triosephosphate Isomerase: Enzyme-Activation by Phosphite Dianion. Carbon 45-51 triosephosphate isomerase 1 Homo sapiens 65-90 24503195-1 2014 A highly sensitive ionic liquid-multiwall carbon nanotube based impedimetric immunosensor modified with gold nanoparticles (GNPs) was developed for the determination of human serum albumin (HSA). Carbon 42-48 albumin Homo sapiens 175-188 24729658-1 2014 The mechanistic imperatives for catalysis of deprotonation of alpha-carbonyl carbon by triosephosphate isomerase (TIM) are discussed. Carbon 68-74 triosephosphate isomerase 1 Homo sapiens 87-112 24729658-1 2014 The mechanistic imperatives for catalysis of deprotonation of alpha-carbonyl carbon by triosephosphate isomerase (TIM) are discussed. Carbon 68-74 triosephosphate isomerase 1 Homo sapiens 114-117 24636417-0 2014 Amorphous carbon nanoparticle used as novel resonance energy transfer acceptor for chemiluminescent immunoassay of transferrin. Carbon 10-16 transferrin Homo sapiens 115-126 24729658-7 2014 Our experiments link the two imperatives for TIM-catalyzed deprotonation of carbon by providing evidence that the phosphodianion binding energy is utilized to drive an enzyme conformational change, which results in a reduction in the thermodynamic barrier to deprotonation of the carbon acid substrate at TIM compared with the barrier for deprotonation in water. Carbon 76-82 triosephosphate isomerase 1 Homo sapiens 45-48 24729658-7 2014 Our experiments link the two imperatives for TIM-catalyzed deprotonation of carbon by providing evidence that the phosphodianion binding energy is utilized to drive an enzyme conformational change, which results in a reduction in the thermodynamic barrier to deprotonation of the carbon acid substrate at TIM compared with the barrier for deprotonation in water. Carbon 76-82 triosephosphate isomerase 1 Homo sapiens 305-308 24566535-5 2014 Under carbon- and nitrogen-starved conditions, the number and size of vesicles labeled by GFP-ATG8 was increased for several hours and then gradually decreased to a level higher than that observed before the start of the experiment. Carbon 6-12 ubiquitin-like protein ATG8 Saccharomyces cerevisiae S288C 94-98 24211460-1 2014 Cholesterol oxidase (ChOx) and catalase (CAT) were co-immobilized on a graphene/ionic liquid-modified glassy carbon electrode (GR-IL/GCE) to develop a highly sensitive amperometric cholesterol biosensor. Carbon 109-115 catalase Homo sapiens 31-39 24492244-1 2014 Allylic rearrangement or the migration of a double bond from its original position in the carbon skeleton to an adjacent site was observed when 3,4,5,6-tetrahydrophthalate was hydrolyzed in a basic solution and in the presence of Co(ii) and Mn(ii) under hydrothermal conditions. Carbon 90-96 mitochondrially encoded cytochrome c oxidase II Homo sapiens 230-236 24492244-1 2014 Allylic rearrangement or the migration of a double bond from its original position in the carbon skeleton to an adjacent site was observed when 3,4,5,6-tetrahydrophthalate was hydrolyzed in a basic solution and in the presence of Co(ii) and Mn(ii) under hydrothermal conditions. Carbon 90-96 mitochondrially encoded cytochrome c oxidase II Homo sapiens 233-235 24184599-3 2014 On the basis of the effect of OPs on the ECL signal of AChE-QDs-GNs modified glassy carbon electrode (GCE), a highly sensitive GNs-anchored-QDs-based signal-on ECL biosensor was developed for sensing OPs, combined with the enzymatic reactions and the dissolved oxygen as coreactant. Carbon 84-90 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-59 24161565-2 2014 Thanks to the unique structure and properties of Pd nanoplates, the antibody of AFP (Ab) was effectively immobilized onto the surface of the Pd nanoplates modified glassy carbon electrode (GCE). Carbon 171-177 alpha fetoprotein Homo sapiens 80-83 24211460-1 2014 Cholesterol oxidase (ChOx) and catalase (CAT) were co-immobilized on a graphene/ionic liquid-modified glassy carbon electrode (GR-IL/GCE) to develop a highly sensitive amperometric cholesterol biosensor. Carbon 109-115 catalase Homo sapiens 41-44 24469104-6 2014 We have also optimized the conditions of the FDH adsorption on carbon cryogel electrodes. Carbon 63-69 aldehyde dehydrogenase 1 family member L1 Homo sapiens 45-48 24347608-0 2014 Carbon ion radiotherapy of human lung cancer attenuates HIF-1 signaling and acts with considerably enhanced therapeutic efficiency. Carbon 0-6 hypoxia inducible factor 1 subunit alpha Homo sapiens 56-61 24611026-2 2014 Calculations at the DFT and coupled Hartree-Fock levels confirm that sp2 cycles of bare carbon centres isolated by selective hydrogenation retain the essentially planar geometry and electron delocalization of the annulene that they mimic. Carbon 88-94 Sp2 transcription factor Homo sapiens 69-72 28788540-1 2014 This study aimed to prepare titania (TiO2) nanotube (TNT) arrays grown on un-activated carbon fibers (UCFs), with the application of different TiO2 loadings based on the coating-hydrothermal process, and to evaluate their photocatalytic activity for the degradation of sub-ppm levels of aromatic pollutants (benzene, toluene, ethyl benzene, and o-xylene (BTEX)) using a plug-flow photocatalytic reactor. Carbon 87-93 chromosome 16 open reading frame 82 Homo sapiens 53-56 24590495-1 2014 The direct alpha-siladifluoromethylation of lithium enolates with the Ruppert-Prakash reagent (CF3 TMS) is shown to construct the tertiary and quaternary carbon centers. Carbon 154-160 PYD and CARD domain containing Homo sapiens 99-102 24296030-6 2014 The low-carbon components of diesel oil volatilize more rapidly, with the effects of wind speed more pronounced on C10 to C15 volatilization than on C16 and higher. Carbon 8-14 homeobox C10 Homo sapiens 115-118 24170365-1 2014 A novel uniform amorphous carbon-coated SnO2 nanocrystal (NCs) for use in lithium-ion batteries is formed by utilizing bovine serum albumin (BSA) as both the ligand and carbon source. Carbon 26-32 albumin Homo sapiens 126-139 24597901-9 2014 Our results suggest that structural characteristics, such as degrees of saturation, types of carbon skeleton and functional group, and hydrophobicity appear to play a role in determining inhibitory potency of curcuminoids on BACE-1. Carbon 93-99 beta-secretase 1 Homo sapiens 225-231 23966175-4 2014 In this work, a rapid, quantitative, and label-free assay, which is specific for cardiac troponin T (cTnT) detection, using fluorescent single-walled carbon nanotubes (SWCNTs), is demonstrated. Carbon 150-156 troponin T2, cardiac type Homo sapiens 81-99 23966175-4 2014 In this work, a rapid, quantitative, and label-free assay, which is specific for cardiac troponin T (cTnT) detection, using fluorescent single-walled carbon nanotubes (SWCNTs), is demonstrated. Carbon 150-156 troponin T2, cardiac type Homo sapiens 101-105 24347608-4 2014 We analyzed the effect of HIF-1 signaling after carbon ions in comparison to photons by using biological equivalent radiation doses in a human non-small-cell cancer model. Carbon 48-54 hypoxia inducible factor 1 subunit alpha Homo sapiens 26-31 24347608-10 2014 After carbon ion irradiation in vivo, we observed substantially decreased HIF-1alpha levels (8.9-fold; P<0.01) and drastically delayed tumor growth (P<0.01), an important finding that indicates a higher relative biological effectiveness (RBE) than anticipated from the cell survival data. Carbon 6-12 hypoxia inducible factor 1 subunit alpha Homo sapiens 74-84 24745229-3 2014 The reaction is facile and completed within few minutes to form insoluble carbon (C-dots) mostly having the graphitic (G-band, Raman) sp2 hybridized carbon atoms (C-atoms). Carbon 74-80 Sp2 transcription factor Homo sapiens 134-137 24881365-2 2014 Eight kinds of carbons were analyzed by the TOR method. Carbon 15-22 RAR related orphan receptor C Homo sapiens 44-47 24745229-3 2014 The reaction is facile and completed within few minutes to form insoluble carbon (C-dots) mostly having the graphitic (G-band, Raman) sp2 hybridized carbon atoms (C-atoms). Carbon 82-83 Sp2 transcription factor Homo sapiens 134-137 24745229-3 2014 The reaction is facile and completed within few minutes to form insoluble carbon (C-dots) mostly having the graphitic (G-band, Raman) sp2 hybridized carbon atoms (C-atoms). Carbon 149-155 Sp2 transcription factor Homo sapiens 134-137 24745229-4 2014 This insoluble carbon on oxidative treatment with nitric acid produced disordered sp3 (D-band retaining G-band, Raman) hybridized C-atoms, originated from the graphitic pool with sp2 hybridized C-atoms. Carbon 15-21 Sp3 transcription factor Homo sapiens 82-85 24745229-4 2014 This insoluble carbon on oxidative treatment with nitric acid produced disordered sp3 (D-band retaining G-band, Raman) hybridized C-atoms, originated from the graphitic pool with sp2 hybridized C-atoms. Carbon 15-21 Sp2 transcription factor Homo sapiens 179-182 24431218-0 2014 Vascular effects of multiwalled carbon nanotubes in dyslipidemic ApoE-/- mice and cultured endothelial cells. Carbon 32-38 apolipoprotein E Mus musculus 65-69 24119415-8 2014 Overall, the pattern of change in light utilization parameters and plastoquinol level indicated that loss of AtLHCB7 expression led to slower Rubisco turnover characterized by pH-dependent balancing of electron transport to reduced carbon assimilation capacity (photosynthetic control). Carbon 232-238 Chlorophyll A-B binding family protein Arabidopsis thaliana 109-116 24450965-1 2014 Rigorous quantum chemical investigations of the SN2 identity exchange reactions of methyl, ethyl, propyl, allyl, benzyl, propargyl, and acetonitrile halides (X = F(-), Cl(-)) refute the traditional view that the acceleration of SN2 reactions for substrates with a multiple bond at Cbeta (carbon adjacent to the reacting Calpha center) is primarily due to pi-conjugation in the SN2 transition state (TS). Carbon 288-294 solute carrier family 38 member 5 Homo sapiens 48-51 24055935-1 2014 This work presents a novel bienzymatic biosensor for the simultaneous determination of nitrite (NO2(-)) and nitrate (NO3(-)) ions using copper, zinc superoxide dismutase (SOD1) and nitrate reductase (NaR) coimmobilized on carbon nanotubes (CNT)-polypyrrole (PPy) nanocomposite modified platinum electrode. Carbon 222-228 superoxide dismutase 1 Homo sapiens 171-175 24494989-2 2014 The highly reversible electrochemical reactivity of CFx with Na at room temperature indicates that the decomposition of NaF could be driven by carbon formed during the first discharge. Carbon 143-149 C-X-C motif chemokine ligand 8 Homo sapiens 120-123 24562332-2 2014 These enzymes employ radical generating capability of coenzyme B12 (5"-deoxyadenosylcobalamin, dAdoCbl) and ability of pyridoxal-5"-phosphate (PLP, vitamin B6) to stabilize high-energy intermediates for performing challenging 1,2-amino rearrangements between adjacent carbons. Carbon 268-275 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 63-66 23922098-10 2014 To our best knowledge, the role of GNMT in folate dependent 1-carbon transfer in nucleotide biosynthesis has never been investigated. Carbon 62-68 glycine N-methyltransferase Homo sapiens 35-39 24035852-0 2014 Electrochemical immunosensor for the determination of insulin-like growth factor-1 using electrodes modified with carbon nanotubes-poly(pyrrole propionic acid) hybrids. Carbon 114-120 insulin like growth factor 1 Homo sapiens 54-82 26276595-0 2014 CCl Radicals As a Carbon Source for Diamond Thin Film Deposition. Carbon 18-24 crystallin gamma E, pseudogene Homo sapiens 0-3 24445127-2 2014 A GAMM with time, geographical zone, periodicity and the organic carbon - water partition coefficient as covariates explained 49% of the variability in the log transformed PCB sediment concentrations. Carbon 65-71 pyruvate carboxylase Homo sapiens 172-175 24417432-4 2014 Carbon nanotube forests grown on Inconel substrates are superior to the ones grown on silicon; low turn-on fields (~1.5 V/mum), high current operation (~100 mA/cm(2)) and very high local field amplification factors (up to ~7300) were demonstrated, and these parameters are most beneficial for use in vacuum microelectronic applications. Carbon 0-6 latexin Homo sapiens 122-125 24533076-1 2014 BACKGROUND: Genome-wide association studies on components of the one-carbon metabolic pathway revealed that human vitamin B12 levels could be significantly influenced by variations in the fucosyltransferase 2 (FUT2), cubilin (CUBN), and transcobalamin-I (TCN1) genes. Carbon 69-75 fucosyltransferase 2 Homo sapiens 188-208 24479838-1 2014 The alkylation of (Z)-3-aryl-2-fluoroallyl acetate with the malonate anion by the [Pd(C3H5)(cod)]BF4/2,2"-bpy catalyst proceeds through the carbon-fluorine bond cleavage, and 2 equiv of the malonate nucleophile was introduced to the allyl substrate. Carbon 140-146 forkhead box G1 Homo sapiens 97-102 24499918-5 2014 We find that the Amazon basin lost 0.48 +- 0.18 petagrams of carbon per year (Pg C yr(-1)) during the dry year but was carbon neutral (0.06 +- 0.1 Pg C yr(-1)) during the wet year. Carbon 61-67 progastricsin Homo sapiens 78-82 24499918-7 2014 During the wet year, vegetation was a net carbon sink of 0.25 +- 0.14 Pg C yr(-1), which is roughly consistent with the mean long-term intact-forest biomass sink of 0.39 +- 0.10 Pg C yr(-1) previously estimated from forest censuses. Carbon 42-48 progastricsin Homo sapiens 70-74 26276595-5 2014 Our results also suggest that further reductions in substrate temperatures are possible from using CCl as the only carbon source. Carbon 115-121 crystallin gamma E, pseudogene Homo sapiens 99-102 24411376-1 2014 A novel acetylcholinesterase (AChE) biosensor based on Ag NPs, carboxylic graphene (CGR) and Nafion (NF) hybrid modified glass carbon electrode (GCE) has been successfully developed. Carbon 127-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 8-28 23955578-0 2014 Single-walled carbon nanotubes induce cell death and transcription of TNF-alpha in macrophages without affecting nitric oxide production. Carbon 14-20 tumor necrosis factor Homo sapiens 70-79 25419449-1 2014 We report mechanistic aspects of the trapping of thermally (HDDA) generated benzyne derivatives by pendant silyl ether groups, which results in net insertion of the pair of benzyne Csp-hydribized carbon atoms into the silicon-oxygen sigma bond. Carbon 196-202 DnaJ heat shock protein family (Hsp40) member C5 Homo sapiens 181-184 24411376-1 2014 A novel acetylcholinesterase (AChE) biosensor based on Ag NPs, carboxylic graphene (CGR) and Nafion (NF) hybrid modified glass carbon electrode (GCE) has been successfully developed. Carbon 127-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 30-34 24587704-2 2014 The product is proved to have a sp2 hybrid carbon skeleton with polysulfide attached on it. Carbon 43-49 Sp2 transcription factor Homo sapiens 32-35 24342050-0 2014 Development of carbon nanotubes/CoFe2O4 magnetic hybrid material for removal of tetrabromobisphenol A and Pb(II). Carbon 15-21 submaxillary gland androgen regulated protein 3B Homo sapiens 106-112 24475979-4 2014 The electrical conduction mechanism of LRS is attributed to conductive sp2 carbon filament with conjugation double bonds by dehydrogenation, while the electrical conduction of HRS resulted from the formation of insulating sp3-type carbon filament through hydrogenation process. Carbon 75-81 Sp2 transcription factor Homo sapiens 71-74 24450435-1 2014 Graphene, the new allotrope of carbon is a single layer of monocrystalline graphite with sp2 hybridized carbon atoms. Carbon 31-37 Sp2 transcription factor Homo sapiens 89-92 23990142-1 2014 Recently, we reported that the novel mitochondrial RNA editing factor SLO2 is essential for mitochondrial electron transport, and vital for plant growth through regulation of carbon and energy metabolism. Carbon 175-181 Pentatricopeptide repeat (PPR) superfamily protein Arabidopsis thaliana 70-74 24299827-2 2014 GC-g-DMA-g-C60 was prepared via the simple two-step chemical grafting reactions of (i) DMA to free amine groups of GC and (ii) hydroxyl groups of GC-g-DMA to pipi carbon bonds of C60. Carbon 163-169 glucagon Homo sapiens 0-4 24299827-2 2014 GC-g-DMA-g-C60 was prepared via the simple two-step chemical grafting reactions of (i) DMA to free amine groups of GC and (ii) hydroxyl groups of GC-g-DMA to pipi carbon bonds of C60. Carbon 163-169 glucagon Homo sapiens 146-150 24292147-1 2014 A new FRET model using near-infrared quantum-dots (NIR-QDs) and oxidized carbon nanoparticles (OCNPs) as the energy donor and acceptor was constructed and designed for insulin detection in complex human plasma. Carbon 73-79 insulin Homo sapiens 168-175 24574900-2 2014 The values of the fraction of near irreversible C m E n micellar trapped 1 molecules (F(IT1)) vary in the range ~0-0.75 for C(12)E(23) and ~0-0.83 for C(18)E(20) under such conditions. Carbon 48-49 HAUS augmin like complex subunit 3 Homo sapiens 86-91 24574900-2 2014 The values of the fraction of near irreversible C m E n micellar trapped 1 molecules (F(IT1)) vary in the range ~0-0.75 for C(12)E(23) and ~0-0.83 for C(18)E(20) under such conditions. Carbon 124-125 HAUS augmin like complex subunit 3 Homo sapiens 86-91 24205509-0 2014 Paper-based colorimetric immunosensor for visual detection of carcinoembryonic antigen based on the high peroxidase-like catalytic performance of ZnFe2O4-multiwalled carbon nanotubes. Carbon 166-172 CEA cell adhesion molecule 3 Homo sapiens 62-86 24339020-1 2014 Unusual chemical transformations such as three-component combination and ring-opening of N-heterocycles or formation of a carbon-carbon double bond through multiple C-H activation were observed in the reactions of Tp(Me2) -supported yttrium alkyl complexes with aromatic N-heterocycles. Carbon 122-128 malic enzyme 2 Homo sapiens 217-220 24339020-1 2014 Unusual chemical transformations such as three-component combination and ring-opening of N-heterocycles or formation of a carbon-carbon double bond through multiple C-H activation were observed in the reactions of Tp(Me2) -supported yttrium alkyl complexes with aromatic N-heterocycles. Carbon 129-135 malic enzyme 2 Homo sapiens 217-220 24205509-1 2014 A new paper-based colorimetric immunosensor for the detection of carcinoembryonic antigen (CEA) was developed based on the intrinsic peroxidase activity of ZnFe2O4-multiwalled carbon nanotubes (ZnFe2O4@MWNTs). Carbon 176-182 CEA cell adhesion molecule 3 Homo sapiens 65-89 24205509-1 2014 A new paper-based colorimetric immunosensor for the detection of carcinoembryonic antigen (CEA) was developed based on the intrinsic peroxidase activity of ZnFe2O4-multiwalled carbon nanotubes (ZnFe2O4@MWNTs). Carbon 176-182 CEA cell adhesion molecule 3 Homo sapiens 91-94 23944933-6 2014 Knockdown of IL-17 receptor (IL-17R) E, the specific receptor for IL-17C, using IL-17RE small interfering RNA, attenuated polyI:C-induced hBD2, CSF3, and S100A12 expression, without any reduction of polyI:C-induced IL-17C expression, which suggest that IL-17C enhances hBD2, CSF, and S100A12 expression in an autocrine/paracrine manner in NHBE cells. Carbon 128-129 defensin beta 4A Homo sapiens 138-142 24664753-2 2014 ELOVL4 catalyzes the initial condensation step in the elongation of polyunsaturated fatty acids (PUFA) containing more than 26 carbons (26C) to very long chain PUFA (VLC-PUFA; C28 and greater). Carbon 127-134 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 Mus musculus 0-6 24405426-5 2014 Of immediate concern are potential carbon losses to deforestation (90-970 Tg C y(-1)) that are greater than these ecosystems" rates of carbon storage. Carbon 35-41 transglutaminase 2 Homo sapiens 74-78 23944933-7 2014 Knockdown of IL-17C also decreased polyI:C-induced hBD2, CSF3, and S100A12 expression. Carbon 18-19 defensin beta 4A Homo sapiens 51-55 25020005-1 2014 Heavy carbon steel corrosion developed during nitrate mitigation of a flow rig connected to a water injection pipeline flowing anaerobe saline aquifer water. Carbon 6-12 dickkopf WNT signaling pathway inhibitor 3 Homo sapiens 75-78 23963510-0 2014 A novel genotoxicity assay of carbon nanotubes using functional macrophage receptor with collagenous structure (MARCO)-expressing chicken B lymphocytes. Carbon 30-36 macrophage receptor with collagenous structure Gallus gallus 64-110 23963510-0 2014 A novel genotoxicity assay of carbon nanotubes using functional macrophage receptor with collagenous structure (MARCO)-expressing chicken B lymphocytes. Carbon 30-36 macrophage receptor with collagenous structure Gallus gallus 112-117 24433396-10 2014 The modeled armchair carbon nanotubes had the binding affinities of -12.4 Kcal/mole, -20 Kcal/mole and -11.7 Kcal/mole with the Vpr, Nef and Gag proteins of HIV. Carbon 21-27 S100 calcium binding protein B Homo sapiens 133-136 24919672-1 2014 A sensitive biosensor based on acetylcholinesterase (AChE) and carbon nanosphere (CNS) immobilized on a glassy carbon electrode was developed for the detection of pesticides by the inhibition of AChE activity. Carbon 63-69 acetylcholinesterase (Cartwright blood group) Homo sapiens 195-199 24919672-1 2014 A sensitive biosensor based on acetylcholinesterase (AChE) and carbon nanosphere (CNS) immobilized on a glassy carbon electrode was developed for the detection of pesticides by the inhibition of AChE activity. Carbon 111-117 acetylcholinesterase (Cartwright blood group) Homo sapiens 195-199 25198751-6 2014 The direct construction of carbon(sp2)-carbon(sp3) bonds via transition metal-mediated cross-coupling reactions represents one of the most straightforward strategies for the introduction of difluoromethylene moieties (CF2R, R F, R(f)) to aromatic compounds. Carbon 27-33 coagulation factor II thrombin receptor Homo sapiens 218-222 25198751-6 2014 The direct construction of carbon(sp2)-carbon(sp3) bonds via transition metal-mediated cross-coupling reactions represents one of the most straightforward strategies for the introduction of difluoromethylene moieties (CF2R, R F, R(f)) to aromatic compounds. Carbon 39-45 coagulation factor II thrombin receptor Homo sapiens 218-222 24032591-9 2014 Our findings demonstrated that intracellular poly(I:C) not only triggered gastric adenocarcinoma cell apoptosis, but also enhanced NK responses via inducing type I IFN production by gastric adenocarcinoma cells. Carbon 52-53 interferon alpha 1 Homo sapiens 164-167 24219896-0 2014 Vitamin B12: one carbon metabolism, fetal growth and programming for chronic disease. Carbon 17-23 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 8-11 24219896-5 2014 Vitamin B12 is a key nutrient associated with one carbon metabolic pathways related to substrate metabolism, synthesis and stability of nucleic acids and methylation of DNA which regulates gene expression. Carbon 50-56 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 8-11 24001830-1 2014 Acetylcholinesterase (AChE) biosensor was developed through silica sol-gel (SiSG) immobilisation of AChE on the carbon paste electrode (CPE) and used as working electrode. Carbon 112-118 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 24001830-1 2014 Acetylcholinesterase (AChE) biosensor was developed through silica sol-gel (SiSG) immobilisation of AChE on the carbon paste electrode (CPE) and used as working electrode. Carbon 112-118 acetylcholinesterase (Cartwright blood group) Homo sapiens 22-26 24001830-1 2014 Acetylcholinesterase (AChE) biosensor was developed through silica sol-gel (SiSG) immobilisation of AChE on the carbon paste electrode (CPE) and used as working electrode. Carbon 112-118 acetylcholinesterase (Cartwright blood group) Homo sapiens 100-104 25693294-8 2014 There is clear evidence that the carbon-ion irradiation enables the enhanced cell killing in cells with wild-type P53 gene via gap-junction mediated bystander effect. Carbon 33-39 tumor protein p53 Homo sapiens 114-117 24076518-2 2013 A series of human and animal studies in our department have shown that micronutrients (folic acid, vitamin B12) and omega 3 fatty acids like DHA are all interlinked in the one carbon cycle. Carbon 176-182 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 107-110 24372857-5 2014 Flow cytometric analyses revealed that LPS and poly I:C stimulation allows the CD33(+) CD14(+) HLA-DR(-) subset to be significantly increased. Carbon 54-55 CD33 molecule Homo sapiens 79-83 24030902-2 2013 An unexpected novel hybrid state arising from amorphous carbon-like peripheral structure with high sp(3) /sp(2) carbon ratio in close vicinity of confined graphene-like states is found commonly existent in various carbon nanomaterials, including graphene oxide, graphene quantum dots, and carbon dots. Carbon 56-62 Sp3 transcription factor Homo sapiens 99-104 24030902-2 2013 An unexpected novel hybrid state arising from amorphous carbon-like peripheral structure with high sp(3) /sp(2) carbon ratio in close vicinity of confined graphene-like states is found commonly existent in various carbon nanomaterials, including graphene oxide, graphene quantum dots, and carbon dots. Carbon 56-62 Sp2 transcription factor Homo sapiens 106-111 24030902-2 2013 An unexpected novel hybrid state arising from amorphous carbon-like peripheral structure with high sp(3) /sp(2) carbon ratio in close vicinity of confined graphene-like states is found commonly existent in various carbon nanomaterials, including graphene oxide, graphene quantum dots, and carbon dots. Carbon 112-118 Sp3 transcription factor Homo sapiens 99-104 24030902-2 2013 An unexpected novel hybrid state arising from amorphous carbon-like peripheral structure with high sp(3) /sp(2) carbon ratio in close vicinity of confined graphene-like states is found commonly existent in various carbon nanomaterials, including graphene oxide, graphene quantum dots, and carbon dots. Carbon 112-118 Sp2 transcription factor Homo sapiens 106-111 24030902-2 2013 An unexpected novel hybrid state arising from amorphous carbon-like peripheral structure with high sp(3) /sp(2) carbon ratio in close vicinity of confined graphene-like states is found commonly existent in various carbon nanomaterials, including graphene oxide, graphene quantum dots, and carbon dots. Carbon 112-118 Sp3 transcription factor Homo sapiens 99-104 24030902-2 2013 An unexpected novel hybrid state arising from amorphous carbon-like peripheral structure with high sp(3) /sp(2) carbon ratio in close vicinity of confined graphene-like states is found commonly existent in various carbon nanomaterials, including graphene oxide, graphene quantum dots, and carbon dots. Carbon 112-118 Sp2 transcription factor Homo sapiens 106-111 24030902-2 2013 An unexpected novel hybrid state arising from amorphous carbon-like peripheral structure with high sp(3) /sp(2) carbon ratio in close vicinity of confined graphene-like states is found commonly existent in various carbon nanomaterials, including graphene oxide, graphene quantum dots, and carbon dots. Carbon 112-118 Sp3 transcription factor Homo sapiens 99-104 24030902-2 2013 An unexpected novel hybrid state arising from amorphous carbon-like peripheral structure with high sp(3) /sp(2) carbon ratio in close vicinity of confined graphene-like states is found commonly existent in various carbon nanomaterials, including graphene oxide, graphene quantum dots, and carbon dots. Carbon 112-118 Sp2 transcription factor Homo sapiens 106-111 23832232-0 2013 Novel solid-phase extractor based on functionalization of multi-walled carbon nano tubes with 5-aminosalicylic acid for preconcentration of Pb(II) in water samples prior to determination by ICP-OES. Carbon 71-77 submaxillary gland androgen regulated protein 3B Homo sapiens 140-146 24231742-1 2014 This work reports on the photophysical parameters of the conjugate between zinc octacarboxy phthalocyanine (ZnOCPc) and bovine serum albumin (BSA) represented as ZnOCPc-BSA (1) which was further adsorbed onto single walled carbon nanotubes (SWCNT) represented as (ZnOCPc-BSA-SWCNT 2). Carbon 223-229 albumin Homo sapiens 127-140 24231742-1 2014 This work reports on the photophysical parameters of the conjugate between zinc octacarboxy phthalocyanine (ZnOCPc) and bovine serum albumin (BSA) represented as ZnOCPc-BSA (1) which was further adsorbed onto single walled carbon nanotubes (SWCNT) represented as (ZnOCPc-BSA-SWCNT 2). Carbon 241-246 albumin Homo sapiens 127-140 23824663-2 2014 Proline-fueled mitochondrial metabolism involves the oxidative conversion of L-Proline to L-Glutamate in two enzymatic steps by means of Put1p and Put2p that help Saccharomyces cerevisiae to respond to changes in the nutritional environment by initiating the breakdown of L-Proline as a source for nitrogen, carbon, and energy. Carbon 308-314 proline dehydrogenase Saccharomyces cerevisiae S288C 137-142 24231630-1 2013 Spontaneous adsorption of the Abeta peptide on the surface of a single-walled carbon nanotube, resulting in the prevention of its intrinsic propensity to form collapsed states, could be a plausible means to hinder the peptide"s initial nucleation and self-assembly. Carbon 78-84 amyloid beta precursor protein Homo sapiens 30-35 24349223-3 2013 From 2001 to the end of 2010, the forest areas increased more than 2.3 million ha, and total carbon storage in forest ecosystems was 173.02 Tg C, of which 82.80 percent was contained in soil in the top 0-100 cm layer. Carbon 93-99 transglutaminase 2 Homo sapiens 140-144 24322444-0 2013 Carbon nanotube-induced pulmonary granulomatous disease: Twist1 and alveolar macrophage M1 activation. Carbon 0-6 twist family bHLH transcription factor 1 Homo sapiens 57-63 24322444-3 2013 Based on this observation we hypothesized that Twist1 mRNA and protein expression might become elevated in alveolar macrophages from animals bearing granulomas induced by carbon nanotube instillation. Carbon 171-177 twist family bHLH transcription factor 1 Homo sapiens 47-53 24057859-7 2013 In our present study, sheep PBMCs had significantly higher TLR3 mRNA levels, TLR3 specific ligand (Poly I:C) stimulation resulted in increased levels of IFN-gamma at transcriptional and translational levels along with IL-8 and IL-10 at transcriptional levels. Carbon 31-32 interleukin-10 Ovis aries 227-232 24140860-5 2013 Surprisingly, we revealed that valerate, hexanoate, and heptanoate with 5-7 carbons are more potent than 4-carbon butyrate in promoting LL-37 gene expression in both cell types. Carbon 76-83 cathelicidin antimicrobial peptide Homo sapiens 136-141 24140860-6 2013 Free fatty acids with longer than 7 or shorter than 4 carbons showed only a marginal effect on LL-37 expression. Carbon 54-61 cathelicidin antimicrobial peptide Homo sapiens 95-100 23966063-0 2013 Carbon-coated Li3 N nanofibers for advanced hydrogen storage. Carbon 0-6 cytochrome P450 family 4 subfamily F member 22 Homo sapiens 14-17 24081001-0 2013 A highly sensitive electrochemical aptasensor for thrombin detection using functionalized mesoporous silica@multiwalled carbon nanotubes as signal tags and DNAzyme signal amplification. Carbon 120-126 coagulation factor II, thrombin Homo sapiens 50-58 23650105-0 2013 Multiwall carbon nanotubes mediate macrophage activation and promote pulmonary fibrosis through TGF-beta/Smad signaling pathway. Carbon 10-16 transforming growth factor, beta 1 Rattus norvegicus 96-104 23966063-1 2013 3D porous carbon-coated Li3 N nanofibers are successfully fabricated via the electrospinning technique. Carbon 10-16 cytochrome P450 family 4 subfamily F member 22 Homo sapiens 24-27 24253851-0 2013 Conversion of multilayer graphene into continuous ultrathin sp3-bonded carbon films on metal surfaces. Carbon 71-77 Sp3 transcription factor Homo sapiens 60-63 23708814-1 2013 A sensitive amperometric acetylcholinesterase (AChE) biosensor, based on SnO2 nanoparticles (SnO2 NPs), carboxylic graphene (CGR) and nafion (NF) modified glassy carbon electrode (GCE) for the detection of methyl parathion and carbofuran has been developed. Carbon 162-168 acetylcholinesterase (Cartwright blood group) Homo sapiens 25-45 24151962-5 2013 In a model system, the interaction of bovine serum albumin and amyloid beta 42 fibrillar aggregates with carbon-coated cobalt nanoparticles, functionalized with various polymers differing in character, was studied. Carbon 105-111 albumin Homo sapiens 45-58 24156567-0 2013 Potential-assisted adsorption of bovine serum albumin onto optically transparent carbon electrodes. Carbon 81-87 albumin Homo sapiens 40-53 24156567-1 2013 This article describes the effect of the applied potential on the adsorption of bovine serum albumin (BSA) to optically transparent carbon electrodes (OTCE). Carbon 132-138 albumin Homo sapiens 87-100 24233717-1 2013 Cytochrome P450 enzymes activate oxygen at heme iron centers to oxidize relatively inert substrate carbon-hydrogen bonds. Carbon 99-105 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-15 23529407-6 2013 Values of C/N ratio higher than 20 mg TOC/mg NO3-N and values of HRT lower than 4.5 h produce differences of up to 46 % with a traditional model that does not include pH calculation inside the biofilm. Carbon 10-11 NBL1, DAN family BMP antagonist Homo sapiens 45-48 24125596-6 2013 The favorable insertion couples the metal-bonded carbon with the methyl-substituted carbon of MeC CPh. Carbon 49-55 C-C motif chemokine ligand 28 Homo sapiens 94-97 24125596-6 2013 The favorable insertion couples the metal-bonded carbon with the methyl-substituted carbon of MeC CPh. Carbon 84-90 C-C motif chemokine ligand 28 Homo sapiens 94-97 24187982-8 2013 The enamido complex 9 reacts via beta-carbon methylation to give the primary imino complex cis-[Re(PNP(tBu)-HN CC(Me)Ph)(CO)2]OTf 11. Carbon 38-44 purine nucleoside phosphorylase Homo sapiens 99-102 24148375-0 2013 Synthesis of fluorescent carbon dots via simple acid hydrolysis of bovine serum albumin and its potential as sensitive sensing probe for lead (II) ions. Carbon 25-31 albumin Homo sapiens 80-87 24148375-2 2013 This work reports a simple and novel synthesis method of carbon dots via direct acid hydrolysis of bovine serum albumin protein in a one-pot approach. Carbon 57-63 albumin Homo sapiens 106-119 24192198-1 2013 The molecular structure of the title compound, C21H19Cl2N3O2, a potent glycogen phosphorylase a (GPa) inhibitor (IC50 of 6.3 microM), consists of four distinct conjugated pi systems separated by rotatable C-C bonds at the methylene groups. Carbon 47-48 glycophorin A (MNS blood group) Homo sapiens 71-95 24192198-1 2013 The molecular structure of the title compound, C21H19Cl2N3O2, a potent glycogen phosphorylase a (GPa) inhibitor (IC50 of 6.3 microM), consists of four distinct conjugated pi systems separated by rotatable C-C bonds at the methylene groups. Carbon 47-48 glycophorin A (MNS blood group) Homo sapiens 97-100 23995325-7 2013 Here we show that a TiC-based cathode reduces greatly side reactions (arising from the electrolyte and electrode degradation) compared with carbon and exhibits better reversible formation/decomposition of Li2O2 even than nanoporous gold (>98% capacity retention after 100 cycles, compared with 95% for nanoporous gold); it is also four times lighter, of lower cost and easier to fabricate. Carbon 140-146 pleckstrin and Sec7 domain containing 4 Homo sapiens 20-23 24051074-1 2013 For further investigation of BACE1 inhibitors using conformational restriction with sp(3) hybridized carbon, we applied this approach to 6-substituted aminopyrimidone derivatives 3 to improve the inhibitory activity by reducing the entropic energy loss upon binding to BACE1. Carbon 101-107 beta-secretase 1 Homo sapiens 29-34 23974165-0 2013 Sediment pore water distribution coefficients of PCB congeners in enriched black carbon sediment. Carbon 81-87 pyruvate carboxylase Homo sapiens 49-52 23661628-7 2013 Thus, the uptake of glucose and glutamine and utilization of the carbon sources derived from them, coordinated by HIF1alpha and c-Myc, are essential for osteoclast development and bone-resorbing activity through a balanced regulation of the nutrient and energy sensors, mTOR and AMPK. Carbon 65-71 hypoxia inducible factor 1 subunit alpha Homo sapiens 114-123 23661628-7 2013 Thus, the uptake of glucose and glutamine and utilization of the carbon sources derived from them, coordinated by HIF1alpha and c-Myc, are essential for osteoclast development and bone-resorbing activity through a balanced regulation of the nutrient and energy sensors, mTOR and AMPK. Carbon 65-71 mechanistic target of rapamycin kinase Homo sapiens 270-274 23937913-0 2013 Targeting colorectal cancer cells with single-walled carbon nanotubes conjugated to anticancer agent SN-38 and EGFR antibody. Carbon 53-59 epidermal growth factor receptor Homo sapiens 111-115 23937913-1 2013 In this study, single-walled carbon nanotubes (SWNTs) conjugated with antibody C225 were used to achieve targeted therapy against EGFR over-expressed colorectal cancer cells. Carbon 29-35 epidermal growth factor receptor Homo sapiens 130-134 23777789-0 2013 On the behavior of acetylcholinesterase immobilized on carbon nanotubes in the presence of inhibitors. Carbon 55-61 acetylcholinesterase (Cartwright blood group) Homo sapiens 19-39 23777789-1 2013 The behavior of acetylcholinesterase before and after click-chemistry reaction on carbon nanotubes was evaluated by kinetic parameters from Michaelis-Menten equation. Carbon 82-88 acetylcholinesterase (Cartwright blood group) Homo sapiens 16-36 23807519-7 2013 Among those started on insulin at initial diagnosis, there was significant improvement in glycemic outcomes (P<.0001 on insulin vs. P = .02 not on insulin) and dyslipidemia (total cholesterol [TC] [P = .001], LDL-C [P = .02], HDL-C [P = .01], non-HDL-C [P = .0002], and TC/HDL-C [P = .005]) compared with no significant change among those who did not receive insulin at diagnosis. Carbon 215-217 insulin Homo sapiens 23-30 24024582-1 2013 An aspargine-glycine-arginine (NGR) peptide modified single-walled carbon nanotubes (SWCNTs) system, developed by a simple non-covalent approach, could be loaded with the anticancer drug tamoxifen (TAM). Carbon 67-73 reticulon 4 receptor Mus musculus 31-34 24428086-8 2013 CONCLUSION: The presence of a high N/C ratio and greater nuclear hyperchromasia could be used to predict high-grade CIN or invasive carcinoma in ASC-H smears. Carbon 0-1 PYD and CARD domain containing Homo sapiens 145-148 24033804-6 2013 Loss-of-function cml39 mutants resemble wild-type plants under normal growth conditions but exhibit persistent arrest at the seedling stage if grown in the absence of sucrose or other metabolizable carbon sources. Carbon 198-204 Calcium-binding EF-hand family protein Arabidopsis thaliana 17-22 24111489-5 2013 The second is a nucleophilic attack on the carbonyl carbon of a Tyr residue of substrate by the negatively charged Thr1-O(gamma), followed by the dissociation of the amine AMC (third step). Carbon 43-49 thyroid hormone receptor beta Homo sapiens 115-119 24111489-6 2013 The fourth step is a nucleophilic attack on the carbonyl carbon of the Tyr residue of substrate by a water molecule, accompanied by a proton transfer from the water molecule to Thr1-N(z). Carbon 48-54 thyroid hormone receptor beta Homo sapiens 177-181 24160772-8 2013 An eGFR < 60 was found in 90% of the subjects aged 85 years as calculated by C-G, in 55% of the subjects using MDRD and in 68% of the 85 year old subjects as calculated by CKD-EPI. Carbon 80-81 epidermal growth factor receptor Homo sapiens 3-7 24147035-9 2013 Repeated administration of poly I:C to C57BL/6.NOD-Aec1Aec2 mice accelerated the development of SS-like exocrinopathy, and this effect was abolished by the blockade of IL-7 receptor signaling with a neutralizing antibody. Carbon 34-35 interleukin 7 Mus musculus 168-172 24108357-2 2013 AMPK"s homolog in the yeast Saccharomyces cerevisiae, the SNF1 protein kinase, is a central regulator of carbon metabolism that inhibits the Snf3/Rgt2-Rgt1 glucose sensing pathway and activates genes involved in respiration. Carbon 105-111 glucose sensor Saccharomyces cerevisiae S288C 141-145 24144230-6 2013 CONCLUSIONS: We observe that transformations which increased polarity (for example adding an oxygen, or an sp2 nitrogen), decreased lipophilicity (removing carbons), or decreased positive charge consistently reduced hERG inhibition between 3- and 10-fold. Carbon 156-163 ETS transcription factor ERG Homo sapiens 216-220 24000351-1 2013 The reaction site of the Co(II) porphyrin created by an amide group and coordinating 1,2-dimethylimidazole at the fifth site activated an O2 molecule, and then hydroxylated the meso-carbon of the ligand. Carbon 182-188 mitochondrially encoded cytochrome c oxidase II Homo sapiens 25-31 23692761-2 2013 The biosensor is based on the activity of fructose dehydrogenase (FDH) immobilised into a carbon nanotube paste electrode according to two different procedures. Carbon 90-96 aldehyde dehydrogenase 1 family member L1 Homo sapiens 42-64 23194105-1 2013 The properties of sp2 carbon allotropes can be tuned and enriched by their interaction with other materials. Carbon 22-28 Sp2 transcription factor Homo sapiens 18-21 24129792-4 2013 It is discovered that it is the interactions of base pair cytosines with each other to form sp2 carbon-like centers as luminescence centers or chromophores for the photoluminescence. Carbon 96-102 Sp2 transcription factor Homo sapiens 92-95 23692761-2 2013 The biosensor is based on the activity of fructose dehydrogenase (FDH) immobilised into a carbon nanotube paste electrode according to two different procedures. Carbon 90-96 aldehyde dehydrogenase 1 family member L1 Homo sapiens 66-69 24020636-0 2013 Analysis of the activation of acetylcholinesterase by carbon nanoparticles using a monolithic immobilized enzyme microreactor: role of the water molecules in the active site gorge. Carbon 54-60 acetylcholinesterase (Cartwright blood group) Homo sapiens 30-50 24013118-3 2013 Herein, we demonstrate that among the FoxO3-regulated genes in NPCs are a host of enzymes in central carbon metabolism that act to combat reactive oxygen species (ROS) by directing the flow of glucose and glutamine carbon into defined metabolic pathways. Carbon 101-107 forkhead box O3 Homo sapiens 38-43 24013118-3 2013 Herein, we demonstrate that among the FoxO3-regulated genes in NPCs are a host of enzymes in central carbon metabolism that act to combat reactive oxygen species (ROS) by directing the flow of glucose and glutamine carbon into defined metabolic pathways. Carbon 215-221 forkhead box O3 Homo sapiens 38-43 24088070-4 2013 For example, the literature now includes misassigned vibration modes, inappropriate spectral processing techniques, confocal depth of laser penetration incorrectly estimated into opaque crystalline solids, and a misconstrued understanding of the anisotropic nature of sp2 carbons. Carbon 272-279 Sp2 transcription factor Homo sapiens 268-271 24053863-6 2013 Although the addition of the graphitized carbon Envi-carb for cleanup decreased the recoveries of zolpidem and its carboxylate-form metabolite M-1, it was very effective in avoiding interferences by cholesterol. Carbon 41-47 myoregulin Homo sapiens 143-146 24116188-5 2013 Relative to clean tillage, sod culture increased annual soil C sequestration by 2.85 t C ha(-1), suggesting that understory management based on sod culture offers promising potential for soil carbon sequestration. Carbon 192-198 superoxide dismutase 1 Homo sapiens 27-30 24116188-5 2013 Relative to clean tillage, sod culture increased annual soil C sequestration by 2.85 t C ha(-1), suggesting that understory management based on sod culture offers promising potential for soil carbon sequestration. Carbon 192-198 superoxide dismutase 1 Homo sapiens 144-147 24409720-5 2013 And compared with the samples using citric acid or sucrose as carbon source, the sample which was synthetized with mixed carbon source (mixed by citric acid and sucrose) exhibited higher I(D)/I(G) ratios and sp2/sp3 peak area ratios. Carbon 121-127 Sp2 transcription factor Homo sapiens 208-211 24409720-5 2013 And compared with the samples using citric acid or sucrose as carbon source, the sample which was synthetized with mixed carbon source (mixed by citric acid and sucrose) exhibited higher I(D)/I(G) ratios and sp2/sp3 peak area ratios. Carbon 121-127 Sp3 transcription factor Homo sapiens 212-215 24020636-1 2013 A biochromatographic system was used to study the direct effect of carbon nanoparticles (CNPs) on the acetylcholinesterase (AChE) activity. Carbon 67-73 acetylcholinesterase (Cartwright blood group) Homo sapiens 102-122 24020636-1 2013 A biochromatographic system was used to study the direct effect of carbon nanoparticles (CNPs) on the acetylcholinesterase (AChE) activity. Carbon 67-73 acetylcholinesterase (Cartwright blood group) Homo sapiens 124-128 23939808-1 2013 Taking advantage of photothermal conversion, the surface pores of water-dispersible single-walled carbon nanotubes assembled on polymer particles were rapidly closed by NIR irradiation to produce macroporous polymeric microspheres with multiple interconnected chambers. Carbon 98-104 NOC2 like nucleolar associated transcriptional repressor Homo sapiens 169-172 23506951-3 2013 In this study, we prepared magnetic nanoparticles with carbon-coated pure iron (Fe@C) acted as the core, Conjugating with EpCAM monoclonal antibody for immunomagnetic nanoparticles(IMPs). Carbon 55-61 epithelial cell adhesion molecule Homo sapiens 122-127 23506951-7 2013 FROM THE CLINICAL EDITOR: This team of investigators prepared magnetic nanoparticles with carbon-coated pure iron as core and conjugated them with EpCAM monoclonal antibody to form immunomagnetic nanoparticles for circulating tumor cell (CTC) detection. Carbon 90-96 epithelial cell adhesion molecule Homo sapiens 147-152 24056340-0 2013 Brightening of carbon nanotube photoluminescence through the incorporation of sp3 defects. Carbon 15-21 Sp3 transcription factor Homo sapiens 78-81 23640812-4 2013 EXPERIMENTAL DESIGN: N-glycans isolated from plasma samples from 20 cases of lung adenocarcinoma and 20 matched controls were analyzed using nLC-PGC-chip-TOF-MS (where PGC is porous-graphitized carbon). Carbon 194-200 progastricsin Homo sapiens 168-171 23932451-2 2013 Among these hybrids, compounds 4f and 4i, berberine linked with o-methylthiophenyl and o-chlorothiophenyl by a 2-carbon spacer, were observed to be potent inhibitors of AChE, with IC50 values of 0.077 and 0.042 muM, respectively. Carbon 113-119 acetylcholinesterase (Cartwright blood group) Homo sapiens 169-173 23930863-6 2013 After that, the nucleophilic sulfur anion of Cys603 in SENP1 attacked the carbonyl carbon of Gly97 of SUMO1 to trigger the reaction, and then a tetrahedral intermediate and an acyl-enzyme intermediate were generated in turn, leading to the final release of enzyme SENP1 and two products, free SUMO1 and RanGAP1. Carbon 74-80 SUMO specific peptidase 1 Homo sapiens 55-60 23930863-6 2013 After that, the nucleophilic sulfur anion of Cys603 in SENP1 attacked the carbonyl carbon of Gly97 of SUMO1 to trigger the reaction, and then a tetrahedral intermediate and an acyl-enzyme intermediate were generated in turn, leading to the final release of enzyme SENP1 and two products, free SUMO1 and RanGAP1. Carbon 74-80 SUMO specific peptidase 1 Homo sapiens 264-269 23988076-5 2013 The TiC was applied to a vertically aligned carbon nanotube sample and characterized by field emission. Carbon 44-50 pleckstrin and Sec7 domain containing 4 Homo sapiens 4-7 23877321-1 2013 A novel protocol of electrochemical thrombin aptasensor based on a goldnanoparticles/thionine-graphene (AuNPs/Th-G) nanocomposite modified glassy carbon electrode was presented. Carbon 146-152 coagulation factor II, thrombin Homo sapiens 36-44 23708635-1 2013 A sensitive amperometric acetylcholinesterase (AChE) biosensor based on NiO nanoparticles (NiO NPs), carboxylic graphene (CGR) and nafion (NF) modified glassy carbon electrode (GCE) has been developed. Carbon 159-165 acetylcholinesterase (Cartwright blood group) Homo sapiens 25-45 23708635-1 2013 A sensitive amperometric acetylcholinesterase (AChE) biosensor based on NiO nanoparticles (NiO NPs), carboxylic graphene (CGR) and nafion (NF) modified glassy carbon electrode (GCE) has been developed. Carbon 159-165 acetylcholinesterase (Cartwright blood group) Homo sapiens 47-51 23708636-0 2013 Activity of catalase adsorbed to carbon nanotubes: effects of carbon nanotube surface properties. Carbon 33-39 catalase Homo sapiens 12-20 23708636-0 2013 Activity of catalase adsorbed to carbon nanotubes: effects of carbon nanotube surface properties. Carbon 62-68 catalase Homo sapiens 12-20 23866154-8 2013 Source waters with higher dissolved organic carbon levels induced increased DBP formation and caused greater effects in the endpoints related to DNA damage repair, glutathione conjugation/protein damage and the Nrf2 oxidative stress response pathway after disinfection. Carbon 44-50 NFE2 like bZIP transcription factor 2 Homo sapiens 211-215 23708636-4 2013 In this study the adsorption of catalase (CAT) on pristine single-walled carbon nanotubes (SWNT), oxidized single-walled carbon nanotubes (O-SWNT), and multi-walled carbon nanotubes (MWNT) was investigated. Carbon 73-79 catalase Homo sapiens 32-40 23708636-4 2013 In this study the adsorption of catalase (CAT) on pristine single-walled carbon nanotubes (SWNT), oxidized single-walled carbon nanotubes (O-SWNT), and multi-walled carbon nanotubes (MWNT) was investigated. Carbon 73-79 catalase Homo sapiens 42-45 23991014-3 2013 Here, using data compiled from literature review and statistical yearbooks, we estimated that total carbon storage in China"s urban areas was 577 +- 60 Tg C (1 Tg = 10(12) g) in 2006. Carbon 100-106 transglutaminase 2 Homo sapiens 152-156 23887873-5 2013 Tlr4(-/-) mice primed with TLR3 agonist polyinosinic:polycytidylic acid [poly(I:C)] to induce pro-caspase-11 expression were as susceptible as wild-type mice were to sepsis induced by E. coli LPS. Carbon 80-82 toll-like receptor 4 Mus musculus 0-4 23694733-2 2013 The degradation processes of DMP, DBP and DOP were well described by a first-order kinetic, with rate constants of 0.02636, 0.1005 and 0.958h(-1) for DMP, DBP and DOP, respectively, indicating that the photolysis rate of PAEs is related to the number of carbon atoms in molecule. Carbon 254-260 D-box binding PAR bZIP transcription factor Homo sapiens 34-37 23694733-2 2013 The degradation processes of DMP, DBP and DOP were well described by a first-order kinetic, with rate constants of 0.02636, 0.1005 and 0.958h(-1) for DMP, DBP and DOP, respectively, indicating that the photolysis rate of PAEs is related to the number of carbon atoms in molecule. Carbon 254-260 D-box binding PAR bZIP transcription factor Homo sapiens 155-158 23694733-6 2013 The order of stable carbon isotope fractionation of the three PAEs during photolysis, DMP>DBP>DOP, is an inverse function of the number of carbon atoms in molecule. Carbon 20-26 D-box binding PAR bZIP transcription factor Homo sapiens 93-96 23694733-6 2013 The order of stable carbon isotope fractionation of the three PAEs during photolysis, DMP>DBP>DOP, is an inverse function of the number of carbon atoms in molecule. Carbon 145-151 D-box binding PAR bZIP transcription factor Homo sapiens 93-96 24013362-0 2013 DNA-PKcs inhibition sensitizes cancer cells to carbon-ion irradiation via telomere capping disruption. Carbon 47-53 protein kinase, DNA-activated, catalytic subunit Homo sapiens 0-8 24013362-11 2013 Our data demonstrated that MCF-7 and HeLa cells with DNA-PKcs inhibition were more susceptible to carbon-ion irradiation than Those without DNA-PKcs inhibition. Carbon 98-104 protein kinase, DNA-activated, catalytic subunit Homo sapiens 53-61 24013362-12 2013 Even though NHEJ was inhibited by the DNA-PKcs specific inhibitor, NU7026, most DNA damage induced by carbon-ion irradiation was repaired within 24 hours after irradiation in both cell lines. Carbon 102-108 protein kinase, DNA-activated, catalytic subunit Homo sapiens 38-46 24013362-16 2013 Our current data suggested that DNA-PKcs inhibition could enhance cellular sensitivity to carbon-ion radiation via disturbing its functional role in telomere end protection. Carbon 90-96 protein kinase, DNA-activated, catalytic subunit Homo sapiens 32-40 24025839-2 2013 The SN2 reaction proceeds in a very predictable manner: substitution occurs with inversion of stereochemistry, resulting from the "backside attack" of the electrophilic carbon by the nucleophile. Carbon 169-175 solute carrier family 38 member 5 Homo sapiens 4-7 24025839-3 2013 A significant limitation of the SN2 reaction is its intolerance for tertiary carbon atoms: whereas primary and secondary alcohols are viable precursor substrates, tertiary alcohols and their derivatives usually either fail to react or produce stereochemical mixtures of products. Carbon 77-83 solute carrier family 38 member 5 Homo sapiens 32-35 23941465-3 2013 The hydroxylation reaction catalyzed by HPPD displaces the aceto substituent of HPA in a 1,2-shift to form 2,5-dihydroxyphenylacetate (homogentisate, HG), whereas the hydroxylation reaction of HMS places a hydroxyl on the benzylic carbon forming 3"-hydroxyphenylacetate (S-hydroxymandelate, HMA) without ensuing chemistry. Carbon 231-237 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 40-44 23731464-2 2013 AIM: The proposal of this study was to investigate how carbon nanotubes internalized by antigen-presenting cells (APCs) affect the development of encephalitogenic CD4(+) T cells. Carbon 55-61 CD4 molecule Homo sapiens 163-166 23731464-11 2013 The results presented suggest that the stimulation of APCs with carbon nanoparticles prior to neuroantigen presentation affects the development of the Th17 subset of encephalitogenic CD4(+) T lymphocytes and results in less severe EAE. Carbon 64-70 CD4 molecule Homo sapiens 183-186 23860231-0 2013 Cloning and expression analysis of transketolase gene in Cucumis sativus L. Transketolase (TK, EC 2.2.1.1) is a key enzyme in the photosynthetic carbon reduction cycle (Calvin cycle). Carbon 145-151 transketolase Cucumis sativus 35-48 23860231-0 2013 Cloning and expression analysis of transketolase gene in Cucumis sativus L. Transketolase (TK, EC 2.2.1.1) is a key enzyme in the photosynthetic carbon reduction cycle (Calvin cycle). Carbon 145-151 transketolase Cucumis sativus 76-89 23860231-0 2013 Cloning and expression analysis of transketolase gene in Cucumis sativus L. Transketolase (TK, EC 2.2.1.1) is a key enzyme in the photosynthetic carbon reduction cycle (Calvin cycle). Carbon 145-151 transketolase Cucumis sativus 91-93 23447468-0 2013 Biodegradation of single-walled carbon nanotubes by eosinophil peroxidase. Carbon 32-38 eosinophil peroxidase Homo sapiens 52-73 23447468-2 2013 The degradation of single-walled carbon nanotubes (SWCNTs) upon incubation with human EPO and H2O2 is reported. Carbon 33-39 eosinophil peroxidase Homo sapiens 86-89 23991014-7 2013 Examining urban carbon storages over a wide range of spatial extents in China and in the United States, we found a strong linear relationship between total urban carbon storage and total urban area, with a specific urban carbon storage of 16 Tg C for every 1,000 km(2) urban area. Carbon 16-22 transglutaminase 2 Homo sapiens 242-246 23991014-7 2013 Examining urban carbon storages over a wide range of spatial extents in China and in the United States, we found a strong linear relationship between total urban carbon storage and total urban area, with a specific urban carbon storage of 16 Tg C for every 1,000 km(2) urban area. Carbon 162-168 transglutaminase 2 Homo sapiens 242-246 23991014-7 2013 Examining urban carbon storages over a wide range of spatial extents in China and in the United States, we found a strong linear relationship between total urban carbon storage and total urban area, with a specific urban carbon storage of 16 Tg C for every 1,000 km(2) urban area. Carbon 162-168 transglutaminase 2 Homo sapiens 242-246 24010453-2 2013 The surface adsorption of hydrogen induces a hybridization change of carbon from the sp2 to the sp3 bond symmetry, which propagates through the graphene layers, resulting in interlayer carbon bond formation. Carbon 69-75 Sp2 transcription factor Homo sapiens 85-88 23602657-0 2013 Role of soil organic carbon and colloids in sorption and transport of TNT, RDX and HMX in training range soils. Carbon 21-27 chromosome 16 open reading frame 82 Homo sapiens 70-73 24010453-2 2013 The surface adsorption of hydrogen induces a hybridization change of carbon from the sp2 to the sp3 bond symmetry, which propagates through the graphene layers, resulting in interlayer carbon bond formation. Carbon 69-75 Sp3 transcription factor Homo sapiens 96-99 24010453-2 2013 The surface adsorption of hydrogen induces a hybridization change of carbon from the sp2 to the sp3 bond symmetry, which propagates through the graphene layers, resulting in interlayer carbon bond formation. Carbon 185-191 Sp2 transcription factor Homo sapiens 85-88 24010453-2 2013 The surface adsorption of hydrogen induces a hybridization change of carbon from the sp2 to the sp3 bond symmetry, which propagates through the graphene layers, resulting in interlayer carbon bond formation. Carbon 185-191 Sp3 transcription factor Homo sapiens 96-99 24010453-3 2013 The structure is stabilized through the termination of interfacial sp3 carbon atoms by the substrate. Carbon 71-77 Sp3 transcription factor Homo sapiens 67-70 23531859-0 2013 Electrocatalytic oxidation and determination of insulin at nickel oxide nanoparticles-multiwalled carbon nanotube modified screen printed electrode. Carbon 98-104 insulin Homo sapiens 48-55 23747415-0 2013 Albumin reduces thrombogenic potential of single-walled carbon nanotubes. Carbon 56-62 albumin Homo sapiens 0-7 23669261-1 2013 Low concentrations of carbon nanotubes (CNTs) promoted the number of nerve growth factor (NGF)-treated neurons with neurite outgrowth by activating extracellular signal-regulated kinase (ERK), even when MEK inhibitor was added to the neuron culture medium. Carbon 22-28 mitogen-activated protein kinase 1 Homo sapiens 148-185 23669261-1 2013 Low concentrations of carbon nanotubes (CNTs) promoted the number of nerve growth factor (NGF)-treated neurons with neurite outgrowth by activating extracellular signal-regulated kinase (ERK), even when MEK inhibitor was added to the neuron culture medium. Carbon 22-28 mitogen-activated protein kinase 1 Homo sapiens 187-190 23669261-1 2013 Low concentrations of carbon nanotubes (CNTs) promoted the number of nerve growth factor (NGF)-treated neurons with neurite outgrowth by activating extracellular signal-regulated kinase (ERK), even when MEK inhibitor was added to the neuron culture medium. Carbon 22-28 mitogen-activated protein kinase kinase 7 Homo sapiens 203-206 23524103-0 2013 Lysozyme binds onto functionalized carbon nanotubes. Carbon 35-41 lysozyme Homo sapiens 0-8 23607494-8 2013 Furthermore, poly(I:C) and proinflammatory cytokines [(IL-1beta, interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha] induced IL-32 expression strongly in cultured BECs, accompanying the constant expression of TLR-3 and caspase 1. Carbon 20-21 interleukin 1 beta Homo sapiens 55-63 23607494-8 2013 Furthermore, poly(I:C) and proinflammatory cytokines [(IL-1beta, interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha] induced IL-32 expression strongly in cultured BECs, accompanying the constant expression of TLR-3 and caspase 1. Carbon 20-21 interferon gamma Homo sapiens 65-87 23607494-8 2013 Furthermore, poly(I:C) and proinflammatory cytokines [(IL-1beta, interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha] induced IL-32 expression strongly in cultured BECs, accompanying the constant expression of TLR-3 and caspase 1. Carbon 20-21 tumor necrosis factor Homo sapiens 92-126 23607494-8 2013 Furthermore, poly(I:C) and proinflammatory cytokines [(IL-1beta, interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha] induced IL-32 expression strongly in cultured BECs, accompanying the constant expression of TLR-3 and caspase 1. Carbon 20-21 caspase 1 Homo sapiens 230-239 23453262-2 2013 The methyl donor, S-adenosylmethionine (SAM), is biosynthesized from methionine and adenosine triphosphate by methionine adenosyltransferase 2a (Mat2a) in the one-carbon (C1) metabolism pathway. Carbon 163-169 methionine adenosyltransferase 2A Homo sapiens 110-143 24191535-5 2013 The mass concentration of EC in TSP in the plant area was lower than that on the top of coke oven, while the mass concentration of OC in the plant area was significantly higher than that on the top of coke oven. Carbon 26-28 thrombospondin 1 Homo sapiens 32-35 22438032-0 2013 CCR5 plays an important role in resolving an inflammatory response to single-walled carbon nanotubes. Carbon 84-90 chemokine (C-C motif) receptor 5 Mus musculus 0-4 23453262-2 2013 The methyl donor, S-adenosylmethionine (SAM), is biosynthesized from methionine and adenosine triphosphate by methionine adenosyltransferase 2a (Mat2a) in the one-carbon (C1) metabolism pathway. Carbon 163-169 methionine adenosyltransferase 2A Homo sapiens 145-150 23750456-9 2013 Specifically, other than fluorescence emission back to the ground state and transformation to the lowest triplet state T1 through intersystem crossing (ISC), the homolysis of the carbon alpha-bond decarboxylation reaction proceeded simultaneously to give rise to two radical species, one being carboxyl and another being the residual, denoted as FpR. Carbon 179-185 formyl peptide receptor 1 Homo sapiens 346-349 23894396-4 2013 METHODS: We analysed the mRNA expression of Serum Amyloid A (Saa3) in lung tissue from female C57BL/6J mice exposed to different particles including nanomaterials (carbon black and titanium dioxide nanoparticles, multi- and single walled carbon nanotubes), diesel exhaust particles and airborne dust collected at a biofuel plant. Carbon 238-244 serum amyloid A 3 Mus musculus 61-65 23500363-4 2013 Using alpha-fetoprotein as an analyte, the immunosensor was constructed by covalently binding capture antibody to chitosan-carbon nanotubes-poly(diallyldimethylammonium chloride) modified electrode. Carbon 123-129 alpha fetoprotein Homo sapiens 6-23 23733183-11 2013 Given that Tup1 and the metabolic enzymes that control PI(3,5)P2 are highly conserved among eukaryotes, our findings may provide important insights toward understanding glucose/carbon metabolic reprogramming in other eukaryotes, including humans. Carbon 177-183 ubiquilin 3 Homo sapiens 11-15 23718696-10 2013 These results suggest that GSH plays a role in reversible covalent modification of TBQ derived from BHA to Keap1 through the formation of a C-S bond. Carbon 140-141 kelch like ECH associated protein 1 Homo sapiens 107-112 23454738-2 2013 Utilizing the polymer-surfactant complexes (i.e., necklace model) to act as a novel CL microenvironment, a highly selective CL sensing system for the detection of Co(II) has been successfully fabricated based on the CL resonance energy transfer between the Fenton-like reaction and necklace model microenvironment-modulated carbon dots. Carbon 324-330 mitochondrially encoded cytochrome c oxidase II Homo sapiens 163-169 23683835-7 2013 Structure-activity relationship studies suggested that introduction of an NO donor, protection of the catechol structure, and the ether chain of a 2-carbon spacer as a coupling chain on the luteolin scaffold all help increase the AR inhibitory activity of the resulting compound. Carbon 149-155 aldo-keto reductase family 1 member B Homo sapiens 230-232 23758319-0 2013 Carbonaceous impurities in carbon nanotubes are responsible for accelerated electrochemistry of cytochrome c. Carbon 27-33 cytochrome c, somatic Homo sapiens 96-108 23712510-0 2013 Aptamer-based turn-on detection of thrombin in biological fluids based on efficient phosphorescence energy transfer from Mn-doped ZnS quantum dots to carbon nanodots. Carbon 150-156 coagulation factor II, thrombin Homo sapiens 35-43 23671902-0 2013 Solid phase extraction-capillary electrophoresis determination of sulphonamide residues in milk samples by use of C18-carbon nanotubes as hybrid sorbent materials. Carbon 118-124 Bardet-Biedl syndrome 9 Homo sapiens 114-117 23671902-5 2013 Carbon nanotubes retained in the C18 sorbent matrix were found to confer aromatic character, increasing its preconcentration capacity as a result. Carbon 0-6 Bardet-Biedl syndrome 9 Homo sapiens 33-36 23671902-6 2013 The conventional C18 stationary phase played a two-fold role: as a support to retain carbon nanotubes in the cartridge and as a medium to prevent their aggregation. Carbon 85-91 Bardet-Biedl syndrome 9 Homo sapiens 17-20 23758319-2 2013 Here, we wish to address and investigate the apparent "good promotion" of the electron transfer to cytochrome c as previously shown and attributed to the electrocatalytic properties of carbon nanotubes (Wang et al. Carbon 185-191 cytochrome c, somatic Homo sapiens 99-111 23624273-0 2013 CYP1A and POR gene mediated mitochondrial membrane damage induced by carbon nanoparticle in human mesenchymal stem cells. Carbon 69-75 cytochrome p450 oxidoreductase Homo sapiens 10-13 23293887-5 2013 The docking studies of most potent analog (7) with 3D crystal structure of the nuclear factor kappa-B (NF-kappaB) P50 homodimer (PDB ID: 1NFK) revealed that carbonyl group of ester side chain and C-28 carboxylic acid groups were mainly involved in hydrogen bonding interaction. Carbon 196-197 nuclear factor kappa B subunit 1 Homo sapiens 79-101 23293887-5 2013 The docking studies of most potent analog (7) with 3D crystal structure of the nuclear factor kappa-B (NF-kappaB) P50 homodimer (PDB ID: 1NFK) revealed that carbonyl group of ester side chain and C-28 carboxylic acid groups were mainly involved in hydrogen bonding interaction. Carbon 196-197 nuclear factor kappa B subunit 1 Homo sapiens 103-112 23348232-6 2013 RESULTS: Intranasal treatment of poly(I:C) significantly induced airway neutrophilia; production of CXCL1, IFN-beta, and CXCL10; and necrotic cell accumulation in BALF. Carbon 40-41 chemokine (C-X-C motif) ligand 1 Mus musculus 100-105 23499967-1 2013 A sensitive amperometric acetylcholinesterase (AChE) biosensor based on platinum nanoparticles (Pt NPs), carboxylic graphene (CGR), and nafion (NF)-modified glassy carbon electrode (GCE) has been developed. Carbon 164-170 acetylcholinesterase (Cartwright blood group) Homo sapiens 47-51 24027974-4 2013 Elemental carbon (EC) accounted for 9%, 9%, 6% and 4% of PM1.1, PM2.1, PM9.0 and TSP, respectively, meanwhile, organic carbon (OC) accounted for 25%, 24%, 16% and 14% of PM1.1, PM2.1, PM9.0 and TSP, respectively. Carbon 10-16 thrombospondin 1 Homo sapiens 81-84 24027974-4 2013 Elemental carbon (EC) accounted for 9%, 9%, 6% and 4% of PM1.1, PM2.1, PM9.0 and TSP, respectively, meanwhile, organic carbon (OC) accounted for 25%, 24%, 16% and 14% of PM1.1, PM2.1, PM9.0 and TSP, respectively. Carbon 18-20 thrombospondin 1 Homo sapiens 81-84 23980418-0 2013 Formal synthesis of (+)-madindoline A, a potent IL-6 inhibitor, utilizing enzymatic discrimination of quaternary carbon. Carbon 113-119 interleukin 6 Homo sapiens 48-52 23725033-1 2013 Herein we report the mediated electrocatalytic voltammetry of the plant molybdoenzyme nitrate reductase (NR) from Arabidopsis thaliana using the established truncated molybdenum-heme fragment at a glassy carbon (GC) electrode. Carbon 204-210 nitrate reductase 1 Arabidopsis thaliana 86-103 23725033-1 2013 Herein we report the mediated electrocatalytic voltammetry of the plant molybdoenzyme nitrate reductase (NR) from Arabidopsis thaliana using the established truncated molybdenum-heme fragment at a glassy carbon (GC) electrode. Carbon 204-210 nitrate reductase 1 Arabidopsis thaliana 105-107 23921124-2 2013 Using an integrated genomics and 13C-based targeted tracer fate association (TTFA) study, we found that NRF2 regulates miR-1 and miR-206 to direct carbon flux toward the pentose phosphate pathway (PPP) and the tricarboxylic acid (TCA) cycle, reprogramming glucose metabolism. Carbon 147-153 nuclear factor, erythroid derived 2, like 2 Mus musculus 104-108 23143677-1 2013 This is a preliminary cross multidisciplinary theoretical-computational approach for the design of a drug delivery system based on immunoconjugated carbon nanotube against HER2- overexpressing cancer cells. Carbon 148-154 erb-b2 receptor tyrosine kinase 2 Homo sapiens 172-176 23143677-3 2013 Our effort is focused on the computational aided design of a high affinity bispecific anti-HER2 antibody and an opening mechanism of the carbon nanotube (CNT) based cytotoxic carrier for controlling multiple drug release. Carbon 137-143 erb-b2 receptor tyrosine kinase 2 Homo sapiens 91-95 23812185-0 2013 Bright, long-lived and coherent excitons in carbon nanotube quantum dots. Carbon 44-50 AT-rich interaction domain 3A Homo sapiens 0-6 24688953-8 2013 RESULTS: Supplementation with inulin caused a significant reduction in FBS (8.50%), HbA1c (10.40%), total cholesterol (12.90%), triglyceride (23.60 %), LDL-c (35.30 %), LDL-c/HDL-c ratio (16.25%) and TC/HDL-c ratio (25.20%) and increased HDL-c (19.90%). Carbon 37-38 component of oligomeric golgi complex 2 Homo sapiens 152-157 24688953-8 2013 RESULTS: Supplementation with inulin caused a significant reduction in FBS (8.50%), HbA1c (10.40%), total cholesterol (12.90%), triglyceride (23.60 %), LDL-c (35.30 %), LDL-c/HDL-c ratio (16.25%) and TC/HDL-c ratio (25.20%) and increased HDL-c (19.90%). Carbon 37-38 component of oligomeric golgi complex 2 Homo sapiens 169-174 23523335-5 2013 It was found that poly(I:C) and CL097 induced the higher IFN-gamma levels and PRRSV-specific antibodies, comparing with that KV with or without LTA in mice. Carbon 25-26 interferon gamma Mus musculus 57-66 23840713-7 2013 The oxidation of glucose to CO2 and incorporation of glucose-carbon into fatty acids were reduced in brain slices from 15 day-old PDC-deficient females. Carbon 61-67 phosducin Mus musculus 130-133 23688239-1 2013 BF2-complex of meso-free 25-oxasmaragdyrin is synthesized under simple reaction conditions in high yield, and the reactivity of meso-free carbon atom was demonstrated by carrying out functionalization followed by coupling reactions. Carbon 138-144 forkhead box G1 Homo sapiens 0-3 23701017-2 2013 We present porous graphitic carbon particles with covalently attached carboxylic acid groups (carboxylate-PGC) as a new HILIC stationary phase. Carbon 28-34 progastricsin Homo sapiens 106-109 23546219-4 2013 The CASH method combines the advantages of the soft and hard template methods by employing a diblock copolymer, PI-b-PEO, which contains a hydrophilic block and an sp(2)-hybridized-carbon-containing hydrophobic block as a structure-directing agent. Carbon 181-187 CASP8 and FADD like apoptosis regulator Homo sapiens 4-8 23567548-5 2013 Poly(I:C) up-regulated pro-inflammatory cytokines, including TNF-alpha and IL-6, and type I interferons (IFN-alpha/beta). Carbon 7-8 tumor necrosis factor Mus musculus 61-70 23567548-5 2013 Poly(I:C) up-regulated pro-inflammatory cytokines, including TNF-alpha and IL-6, and type I interferons (IFN-alpha/beta). Carbon 7-8 interleukin 6 Mus musculus 75-79 23313881-0 2013 Label-free electrochemical IgE aptasensor based on covalent attachment of aptamer onto multiwalled carbon nanotubes/ionic liquid/chitosan nanocomposite modified electrode. Carbon 99-105 immunoglobulin heavy constant epsilon Homo sapiens 27-30 23363301-0 2013 Impact of carbon ion irradiation on epidermal growth factor receptor signaling and glioma cell migration in comparison to conventional photon irradiation. Carbon 10-16 epidermal growth factor receptor Homo sapiens 36-68 23603336-8 2013 We found that both poly(I:C) and LPS induced IkappaB-alpha degradation and phosphorylation, which resulted in NF-kappaB activation, and capsaicin inhibited this NF-kappaB pathway. Carbon 26-27 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus 45-58 23800962-5 2013 In this article, we show that Arabidopsis AMSH1, an AMSH3-related DUB, interacts with the ESCRT-III subunit vacuolar protein sorting2.1 (VPS2.1) and that impairment of both AMSH1 and VPS2.1 causes early senescence and hypersensitivity to artificial carbon starvation in the dark similar to previously reported autophagy mutants. Carbon 249-255 associated molecule with the SH3 domain of STAM 3 Arabidopsis thaliana 52-57 23581551-5 2013 The fluoroindole compound with three carbons in the side chain and one amide group exhibited a selectivity index of 35 (Ki/IC50) with high inhibition of MPO activity (IC50 = 18 nM), whereas its effect on SERT was in the micromolar range. Carbon 37-44 myeloperoxidase Homo sapiens 153-156 23758938-4 2013 The results showed that high dose of carbon dots could promote the percentages of CD3+ and interferon-gamma (IFN-gamma) secretion and decrease the proportions of CD4+/CD8+ on the first day after administration. Carbon 37-43 interferon gamma Mus musculus 91-107 23758938-4 2013 The results showed that high dose of carbon dots could promote the percentages of CD3+ and interferon-gamma (IFN-gamma) secretion and decrease the proportions of CD4+/CD8+ on the first day after administration. Carbon 37-43 interferon gamma Mus musculus 109-118 23758938-8 2013 It suggests that carbon dots could influence the immune functions of normal BALB/c mice by inducing Th1 and Tc responses and that these effects were not enough to induce the morphological change of the immune organs. Carbon 17-23 negative elongation factor complex member C/D, Th1l Mus musculus 100-103 23695260-4 2013 The structure of DUSP26-C showed a novel type of domain-swapped dimer formed by extensive crossover of the C-terminal alpha7 helix. Carbon 24-25 dual specificity phosphatase 26 Homo sapiens 17-23 23501724-0 2013 Signal amplification aptamer biosensor for thrombin based on a glassy carbon electrode modified with graphene, quantum dots and gold nanoparticles. Carbon 70-76 coagulation factor II, thrombin Homo sapiens 43-51 23402795-6 2013 In particular, we found that several genes in the glutamate receptor signaling pathway, including Gria1 and Slc17a7, showed decreases in promoter-specific histone acetylation, and corresponding gene expression deficits, in polyI:C-exposed offspring at both juvenile and adult ages. Carbon 229-230 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 Mus musculus 108-115 23567694-1 2013 Sorption of phthalic acid esters (PAEs: diethyl phthalate, DEP: dibutyl phthalate, DBP as model compounds) in landfill leachates by activated carbon (AC), carbon nanotubes (CNTs), and biochars, were examined. Carbon 142-148 D-box binding PAR bZIP transcription factor Homo sapiens 83-86 23690925-7 2013 In isolated brown adipose tissue (BAT) cells, MSDC-0602, a PPARgamma-sparing TZD, altered the incorporation of (13)C-labeled carbon from glucose into acetyl CoA. Carbon 125-131 peroxisome proliferator activated receptor gamma Homo sapiens 59-68 23482907-2 2013 The electrodeposition was triggered by applying an optimal potential at -0.30 V vs. SCE, leading to the formation of the p-NP imprinting CS/PTMS/AuNPs hybrid film on a glassy carbon electrode (GCE) with a roughly architectural and conductive nature, as revealed by scanning electron microscopy and electrochemical impedance analysis. Carbon 175-181 purine nucleoside phosphorylase Homo sapiens 121-125 23504317-10 2013 Our findings underscore the role of NNT in regulating central carbon metabolism via redox balance, calling for other mechanisms that coordinate substrate preference to maintain a functional TCA cycle. Carbon 62-68 nicotinamide nucleotide transhydrogenase Homo sapiens 36-39 23475318-0 2013 Acetylcholinesterase immobilization on polyacrylamide/functionalized multi-walled carbon nanotube nanocomposite nanofibrous membrane. Carbon 82-88 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 23454830-1 2013 CYP11A1 can hydroxylate vitamin D3 at carbons 17, 20, 22, and 23, producing a range of secosteroids which are biologically active with respect to their ability to inhibit proliferation and stimulate differentiation of various cell types, including cancer cells. Carbon 38-45 cytochrome P450 family 11 subfamily A member 1 Homo sapiens 0-7 23475318-1 2013 In this work, polyacrylamide/multi-walled carbon nanotubes (MWCNT) solution is electrospun to nanocomposite nanofibrous membranes for acetylcholinesterase enzyme immobilization. Carbon 42-48 acetylcholinesterase (Cartwright blood group) Homo sapiens 134-154 23639512-3 2013 The wild-type p53 codon has two common polymorphic variants from a single-base-pair substitution at codon 72, where either C-C-C encodes proline (p53-p72) or C-G-C encodes arginine (p53-R72). Carbon 123-124 tumor protein p53 Homo sapiens 14-17 23263721-3 2013 OBJECTIVES: The aim of the present study was to evaluate the effect of Roux-en-Y gastric bypass (RYGB) on blood markers of oxidative stress, such as vitamins C and E, beta-carotene, reduced glutathione (GSH), catalase (CAT), ferric reducing antioxidant potential (FRAP), and thiobarbituric acid-reactive substances (TBARS). Carbon 4-5 catalase Homo sapiens 209-217 23263721-3 2013 OBJECTIVES: The aim of the present study was to evaluate the effect of Roux-en-Y gastric bypass (RYGB) on blood markers of oxidative stress, such as vitamins C and E, beta-carotene, reduced glutathione (GSH), catalase (CAT), ferric reducing antioxidant potential (FRAP), and thiobarbituric acid-reactive substances (TBARS). Carbon 4-5 catalase Homo sapiens 219-222 23914538-7 2013 Furthermore, Waters SepPak AC-2 provided good recovery results for pesticides among three types of activated carbon sorbents and the average recovery rates reached 74%. Carbon 109-115 adenylate cyclase 2 Homo sapiens 27-31 23639512-3 2013 The wild-type p53 codon has two common polymorphic variants from a single-base-pair substitution at codon 72, where either C-C-C encodes proline (p53-p72) or C-G-C encodes arginine (p53-R72). Carbon 123-124 tumor protein p53 Homo sapiens 146-149 23639512-3 2013 The wild-type p53 codon has two common polymorphic variants from a single-base-pair substitution at codon 72, where either C-C-C encodes proline (p53-p72) or C-G-C encodes arginine (p53-R72). Carbon 123-124 DEAD-box helicase 17 Homo sapiens 150-153 23639512-3 2013 The wild-type p53 codon has two common polymorphic variants from a single-base-pair substitution at codon 72, where either C-C-C encodes proline (p53-p72) or C-G-C encodes arginine (p53-R72). Carbon 123-124 tumor protein p53 Homo sapiens 146-149 23548381-2 2013 The simulated carbon (C1s) XPS spectra as obtained via B3LYP/6-311G(d,p) or M11/6-311G(d,p) calculations are in good agreement (average mean error <0.3 eV) with the experimental spectra, and good estimates of C1s spectra can be obtained via E(C1s)(exp) = 0.9698EC1s(theory) + 20.34 (in eV) (B3LYP/6-311G(d,p)). Carbon 14-20 complement C1s Homo sapiens 22-25 23148892-4 2013 A comparative genome-wide transcriptional analysis revealed that expression levels of genes involved in carbon metabolism, particularly sucrose and starch catabolism, were found to increase upon the loss of GABA-T function under salt stress conditions. Carbon 104-110 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein Arabidopsis thaliana 207-213 23544362-0 2013 Cobryketone derived from vitamin B12 via palladium-catalyzed cleavage of the sp3-sp3 carbon-carbon bond. Carbon 85-91 Sp3 transcription factor Homo sapiens 77-80 23544362-0 2013 Cobryketone derived from vitamin B12 via palladium-catalyzed cleavage of the sp3-sp3 carbon-carbon bond. Carbon 85-91 Sp3 transcription factor Homo sapiens 81-84 23544362-0 2013 Cobryketone derived from vitamin B12 via palladium-catalyzed cleavage of the sp3-sp3 carbon-carbon bond. Carbon 92-98 Sp3 transcription factor Homo sapiens 77-80 23544362-0 2013 Cobryketone derived from vitamin B12 via palladium-catalyzed cleavage of the sp3-sp3 carbon-carbon bond. Carbon 92-98 Sp3 transcription factor Homo sapiens 81-84 23547954-0 2013 Copper-catalyzed aerobic C(sp2)-H functionalization for C-N bond formation: synthesis of pyrazoles and indazoles. Carbon 0-1 Sp2 transcription factor Homo sapiens 25-30 23548381-2 2013 The simulated carbon (C1s) XPS spectra as obtained via B3LYP/6-311G(d,p) or M11/6-311G(d,p) calculations are in good agreement (average mean error <0.3 eV) with the experimental spectra, and good estimates of C1s spectra can be obtained via E(C1s)(exp) = 0.9698EC1s(theory) + 20.34 (in eV) (B3LYP/6-311G(d,p)). Carbon 14-20 complement C1s Homo sapiens 212-215 23548381-2 2013 The simulated carbon (C1s) XPS spectra as obtained via B3LYP/6-311G(d,p) or M11/6-311G(d,p) calculations are in good agreement (average mean error <0.3 eV) with the experimental spectra, and good estimates of C1s spectra can be obtained via E(C1s)(exp) = 0.9698EC1s(theory) + 20.34 (in eV) (B3LYP/6-311G(d,p)). Carbon 14-20 complement C1s Homo sapiens 212-215 23548381-3 2013 As a result, the simulated C1s XPS spectra can elucidate the binding energies of the different carbon species within an organic layer and, in this way, greatly aid the assignment of complicated C1s XPS spectra. Carbon 95-101 complement C1s Homo sapiens 27-30 23548381-3 2013 As a result, the simulated C1s XPS spectra can elucidate the binding energies of the different carbon species within an organic layer and, in this way, greatly aid the assignment of complicated C1s XPS spectra. Carbon 95-101 complement C1s Homo sapiens 194-197 23601885-0 2013 Disposable immunosensors for C-reactive protein based on carbon nanotubes field effect transistors. Carbon 57-63 C-reactive protein Homo sapiens 29-47 23202341-0 2013 Acetylcholinesterase biosensor based on chitosan/prussian blue/multiwall carbon nanotubes/hollow gold nanospheres nanocomposite film by one-step electrodeposition. Carbon 73-79 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 23601885-1 2013 Label-free immunosensors based on single-walled carbon nanotubes field effect transistor (NTFET) devices were developed for the detection of C-reactive protein (CRP) which is currently the best validated inflammatory biomarker associated with cardiovascular diseases. Carbon 48-54 C-reactive protein Homo sapiens 141-159 23601885-1 2013 Label-free immunosensors based on single-walled carbon nanotubes field effect transistor (NTFET) devices were developed for the detection of C-reactive protein (CRP) which is currently the best validated inflammatory biomarker associated with cardiovascular diseases. Carbon 48-54 C-reactive protein Homo sapiens 161-164 23601885-2 2013 The immunoreaction principle consists in the direct adsorption of CRP specific antibodies (anti-CRP) to single-walled carbon nanotubes (SWCNTs) networks. Carbon 118-124 C-reactive protein Homo sapiens 66-69 23601885-2 2013 The immunoreaction principle consists in the direct adsorption of CRP specific antibodies (anti-CRP) to single-walled carbon nanotubes (SWCNTs) networks. Carbon 118-124 C-reactive protein Homo sapiens 96-99 23462715-3 2013 We found that replacement of the quaternary carbon in the bis-phenol skeleton with silicon increased AR-antagonistic activity and reduced VDR-agonistic activity, that is, the AR selectivity of the silicon-containing compounds was higher than that of corresponding carbon compounds. Carbon 44-50 androgen receptor Homo sapiens 101-103 23723870-5 2013 The C=O group located at the tricyclic fragment is fixed in an s-trans orientation, while the second C=O group adopts an s-cis orientation with respect to the double bonds of the 1,4-DHP ring. Carbon 101-102 dihydropyrimidinase Homo sapiens 183-186 25167297-1 2013 We present a theory of a reversibly deforming sp2-carbon-based system controlled by competing strain, surface, and electrostatic energies, a carbomorph. Carbon 50-56 Sp2 transcription factor Homo sapiens 46-49 25657845-0 2013 Magneto-Fluorescent Carbon Nanotube-Mediated siRNA for Gastrin-Releasing Peptide Receptor Silencing in Neuroblastoma. Carbon 20-26 gastrin releasing peptide receptor Homo sapiens 55-89 25657845-1 2013 We demonstrate a newly-developed magneto-fluorescent carbon nanotube (CNT) mediated siRNA (CNT-siRNA) delivery system, which significantly silences our target of interest, gastrin-releasing peptide receptor (GRP-R), in neuroblastoma. Carbon 53-59 gastrin releasing peptide receptor Homo sapiens 172-206 25657845-1 2013 We demonstrate a newly-developed magneto-fluorescent carbon nanotube (CNT) mediated siRNA (CNT-siRNA) delivery system, which significantly silences our target of interest, gastrin-releasing peptide receptor (GRP-R), in neuroblastoma. Carbon 53-59 gastrin releasing peptide receptor Homo sapiens 208-213 23470096-1 2013 In the presence of Pd(0) and a phosphine, hydrosilylation of 1,3-enynes with Me2SiHCl proceeds to yield dienylsilanes with the silicon function added to the internal alkyne carbon atom and with (E)-configuration of newly formed olefinic bond. Carbon 173-179 malic enzyme 2 Homo sapiens 77-80 23462715-3 2013 We found that replacement of the quaternary carbon in the bis-phenol skeleton with silicon increased AR-antagonistic activity and reduced VDR-agonistic activity, that is, the AR selectivity of the silicon-containing compounds was higher than that of corresponding carbon compounds. Carbon 44-50 androgen receptor Homo sapiens 175-177 23462715-3 2013 We found that replacement of the quaternary carbon in the bis-phenol skeleton with silicon increased AR-antagonistic activity and reduced VDR-agonistic activity, that is, the AR selectivity of the silicon-containing compounds was higher than that of corresponding carbon compounds. Carbon 264-270 androgen receptor Homo sapiens 175-177 23010015-1 2013 A novel label-free immunoassay strategy for sensitive detection of alpha-fetoprotein (AFP) was proposed based on controlled fabrication of single-wall carbon nanotubes (CNTs) inside the channels of mesoporous silica (MPS). Carbon 151-157 alpha fetoprotein Homo sapiens 67-84 23377879-0 2013 Improve carbon metabolic flux in Saccharomyces cerevisiae at high temperature by overexpressed TSL1 gene. Carbon 8-14 trehalose 6-phosphate synthase/phosphatase complex subunit Saccharomyces cerevisiae S288C 95-99 23373840-10 2013 A large thermodynamic drive for the formation of a radical intermediate is encountered in the mechanistic scene, and this intermediate substantially diminishes the energy barrier required for C-H activation by the Fe(V) O species. Carbon 192-193 FEV transcription factor, ETS family member Homo sapiens 214-219 23518598-8 2013 Histological studies showed that nasal nerves expressed both vascular cell adhesion molecule-1 (VCAM-1) and chemokine (C-C motif) ligand 26 (CCL-26). Carbon 97-98 vascular cell adhesion molecule 1 Homo sapiens 61-94 23393182-10 2013 However, lipid oxidative efficiency (CO2 to (14)C-acid soluble metabolites ratio) was enhanced in insulin-resistant vs insulin-sensitive individuals, particularly at the highest palmitate concentration (0.24 +- 0.04 vs 0.12 +- 0.02; P = .02). Carbon 37-38 insulin Homo sapiens 98-105 23598212-3 2013 Cyt c, which was tightly immobilized on the PTCA-graphene modified glassy carbon electrode, maintained its natural conformation. Carbon 74-80 cytochrome c, somatic Homo sapiens 0-5 23530619-0 2013 p53-independent early and late apoptosis is mediated by ceramide after exposure of tumor cells to photon or carbon ion irradiation. Carbon 108-114 tumor protein p53 Homo sapiens 0-3 23010015-1 2013 A novel label-free immunoassay strategy for sensitive detection of alpha-fetoprotein (AFP) was proposed based on controlled fabrication of single-wall carbon nanotubes (CNTs) inside the channels of mesoporous silica (MPS). Carbon 151-157 alpha fetoprotein Homo sapiens 86-89 23390982-2 2013 It represented a highly efficient and selective C-H bond functionalization of pyridine derivatives in the presence of reactive C-Cl or C-Br bonds. Carbon 48-49 cannabinoid receptor 1 Homo sapiens 135-139 23385204-0 2013 Interaction of carbon nanoparticles to serum albumin: elucidation of the extent of perturbation of serum albumin conformations and thermodynamical parameters. Carbon 15-21 albumin Homo sapiens 39-52 23385204-0 2013 Interaction of carbon nanoparticles to serum albumin: elucidation of the extent of perturbation of serum albumin conformations and thermodynamical parameters. Carbon 15-21 albumin Homo sapiens 99-112 23291228-0 2013 Interaction of carboxylated single-walled carbon nanotubes with bovine serum albumin. Carbon 42-48 albumin Homo sapiens 71-84 23485312-7 2013 The C-N product shows a strong emission line centered at 640 nm at 30 GPa, which linearly shifts toward shorter wavelength at the rate of -1.38 nm/GPa. Carbon 4-5 glycophorin A (MNS blood group) Homo sapiens 147-150 23485312-5 2013 On the other hand, laser-heating of the C=N polymer above 25 GPa further converts to a theoretically predicted 3D C-N network structure, evident from an emergence of new Raman nus(C-N) at 1404 cm(-1) at 25 GPa and the visual appearance of translucent solid. Carbon 40-41 glycophorin A (MNS blood group) Homo sapiens 61-64 23266496-1 2013 Electrochemistry of cytochrome c (cyt c) immobilized on a cardiolipin (CL)/phosphatidylcholine (PC) film supported on a glassy carbon electrode was investigated using variable-frequency AC voltammetry. Carbon 127-133 cytochrome c, somatic Homo sapiens 34-39 23485312-5 2013 On the other hand, laser-heating of the C=N polymer above 25 GPa further converts to a theoretically predicted 3D C-N network structure, evident from an emergence of new Raman nus(C-N) at 1404 cm(-1) at 25 GPa and the visual appearance of translucent solid. Carbon 40-41 glycophorin A (MNS blood group) Homo sapiens 206-209 23485312-5 2013 On the other hand, laser-heating of the C=N polymer above 25 GPa further converts to a theoretically predicted 3D C-N network structure, evident from an emergence of new Raman nus(C-N) at 1404 cm(-1) at 25 GPa and the visual appearance of translucent solid. Carbon 114-115 glycophorin A (MNS blood group) Homo sapiens 61-64 23485312-5 2013 On the other hand, laser-heating of the C=N polymer above 25 GPa further converts to a theoretically predicted 3D C-N network structure, evident from an emergence of new Raman nus(C-N) at 1404 cm(-1) at 25 GPa and the visual appearance of translucent solid. Carbon 114-115 glycophorin A (MNS blood group) Homo sapiens 206-209 23485312-6 2013 The C-N product is, however, unstable upon pressure unloading below 10 GPa, resulting in a grayish powder that can be considered as nano-diamonds with high-nitrogen content at ambient pressure. Carbon 4-5 glycophorin A (MNS blood group) Homo sapiens 71-74 23485312-7 2013 The C-N product shows a strong emission line centered at 640 nm at 30 GPa, which linearly shifts toward shorter wavelength at the rate of -1.38 nm/GPa. Carbon 4-5 glycophorin A (MNS blood group) Homo sapiens 70-73 23001007-0 2013 Reduction of furan derivatives by overexpressing NADH-dependent Adh1 improves ethanol fermentation using xylose as sole carbon source with Saccharomyces cerevisiae harboring XR-XDH pathway. Carbon 120-126 alcohol dehydrogenase ADH1 Saccharomyces cerevisiae S288C 64-68 23001007-4 2013 We showed that overexpression of mutant NADH-dependent ADH1 derived from TMB3000 strain in the recombinant Saccharomyces cerevisiae, into which xylose reductase (XR) and xylitol dehydrogenase (XDH) pathway of Pichia stipitis has been introduced, improved ethanol production from xylose as a sole carbon source in the presence of 5-HMF. Carbon 296-302 alcohol dehydrogenase ADH1 Saccharomyces cerevisiae S288C 55-59 23370301-5 2013 C-34 also significantly downregulated the secretion of TNF-alpha, IL-1-beta and IL-6 by murine splenocytes and THP-1 cells against LPS induced levels. Carbon 0-1 tumor necrosis factor Mus musculus 55-64 23274156-1 2013 This manuscript describes results related to the characterization of electrodes modified with a composite of acetylcholinesterase covalently bound to carbon nanotubes (CNT). Carbon 150-156 acetylcholinesterase (Cartwright blood group) Homo sapiens 109-129 23201743-0 2013 Preparation of amphiphilic hollow carbon nanosphere loaded insulin for oral delivery. Carbon 34-40 insulin Homo sapiens 59-66 23201743-1 2013 Hollow amphiphilic carbon nanosphere loaded insulin with biodegradable polymer coating (ACP) for oral delivery, was developed to overcome intestinal epithelial barriers and protect insulin from photolytic enzymes. Carbon 19-25 insulin Homo sapiens 44-51 23201743-1 2013 Hollow amphiphilic carbon nanosphere loaded insulin with biodegradable polymer coating (ACP) for oral delivery, was developed to overcome intestinal epithelial barriers and protect insulin from photolytic enzymes. Carbon 19-25 insulin Homo sapiens 181-188 23370301-5 2013 C-34 also significantly downregulated the secretion of TNF-alpha, IL-1-beta and IL-6 by murine splenocytes and THP-1 cells against LPS induced levels. Carbon 0-1 interleukin 1 beta Mus musculus 66-75 23370301-5 2013 C-34 also significantly downregulated the secretion of TNF-alpha, IL-1-beta and IL-6 by murine splenocytes and THP-1 cells against LPS induced levels. Carbon 0-1 interleukin 6 Mus musculus 80-84 23620996-1 2013 An amperometric biosensor for determination of Cytochrome c (Cyt c) was fabricated by immobilizing Cytochrome c oxidase (COx) onto nickel oxide nanoparticles (NiO-NPs) decorated carboxylated multiwalled carbon nanotubes/polyaniline (NiO-NPs/cMWCNT/PANI) film electrodeposited on the surface of a gold (Au) electrode. Carbon 203-209 cytochrome c, somatic Homo sapiens 47-59 23620996-1 2013 An amperometric biosensor for determination of Cytochrome c (Cyt c) was fabricated by immobilizing Cytochrome c oxidase (COx) onto nickel oxide nanoparticles (NiO-NPs) decorated carboxylated multiwalled carbon nanotubes/polyaniline (NiO-NPs/cMWCNT/PANI) film electrodeposited on the surface of a gold (Au) electrode. Carbon 203-209 cytochrome c, somatic Homo sapiens 61-66 23620996-1 2013 An amperometric biosensor for determination of Cytochrome c (Cyt c) was fabricated by immobilizing Cytochrome c oxidase (COx) onto nickel oxide nanoparticles (NiO-NPs) decorated carboxylated multiwalled carbon nanotubes/polyaniline (NiO-NPs/cMWCNT/PANI) film electrodeposited on the surface of a gold (Au) electrode. Carbon 203-209 cytochrome c, somatic Homo sapiens 99-111 23307693-0 2013 Nitrogen-doped sp2-hybridized carbon as a superior catalyst for selective oxidation. Carbon 30-36 Sp2 transcription factor Homo sapiens 15-18 23173928-6 2013 Finally, we propose a role for harnessing the plant TOR pathway by utilizing it as a potent metabolic switch, offering a possible route for biotechnological optimization of plant energy content and carbon partitioning for the production of bioenergy. Carbon 198-204 target of rapamycin Arabidopsis thaliana 52-55 23244494-2 2013 In particular, it has been shown that 2D molecular descriptors such as fraction of Sp3 carbon atoms (Fsp3) and number of stereo centers correlate with clinical success. Carbon 87-93 Sp3 transcription factor Homo sapiens 83-86 23239109-0 2013 Sp2 C-dominant N-doped carbon sub-micrometer spheres with a tunable size: a versatile platform for highly efficient oxygen-reduction catalysts. Carbon 23-29 Sp2 transcription factor Homo sapiens 0-3 23597989-1 2013 We report on a new approach for the electrochemical detection of hydrogen peroxide (H2O2) based on Cytochrome C (Cyt c) immobilized ionic liquid (IL)-functionalized multi-walled carbon nanotubes (MWCNTs) modified glass carbon electrode (GCE). Carbon 178-184 cytochrome c, somatic Homo sapiens 99-111 23597989-1 2013 We report on a new approach for the electrochemical detection of hydrogen peroxide (H2O2) based on Cytochrome C (Cyt c) immobilized ionic liquid (IL)-functionalized multi-walled carbon nanotubes (MWCNTs) modified glass carbon electrode (GCE). Carbon 178-184 cytochrome c, somatic Homo sapiens 113-118 23597989-1 2013 We report on a new approach for the electrochemical detection of hydrogen peroxide (H2O2) based on Cytochrome C (Cyt c) immobilized ionic liquid (IL)-functionalized multi-walled carbon nanotubes (MWCNTs) modified glass carbon electrode (GCE). Carbon 219-225 cytochrome c, somatic Homo sapiens 99-111 23597989-1 2013 We report on a new approach for the electrochemical detection of hydrogen peroxide (H2O2) based on Cytochrome C (Cyt c) immobilized ionic liquid (IL)-functionalized multi-walled carbon nanotubes (MWCNTs) modified glass carbon electrode (GCE). Carbon 219-225 cytochrome c, somatic Homo sapiens 113-118 23597989-2 2013 Functionalization of multi-walled carbon nanotube with amine-terminated ionic liquid materials was characterized using fourier transform infrared spectroscopy (FTIR), UV-vis spectra, and electrochemical impedance spectroscopy (EIS), and the results showed that the covalent modification of MWCNTs with ILs exhibited a high surface area for enzyme immobilization and provided a good microenvironment for Cyt c to retain its bioelectrocatalytic activity toward H2O2. Carbon 34-40 cytochrome c, somatic Homo sapiens 403-408 23391460-0 2013 Self-assembled monolayers of pyridylthio-functionalized carbon nanotubes used as a support to immobilize cytochrome c. Carbon 56-62 cytochrome c, somatic Homo sapiens 105-117 23184522-8 2013 Consistent with observations in other organisms, the H. capsulatum hcl1 mutant was unable to grow on leucine as the major carbon source, caused acidification of its growth medium in vitro, and resided in an acidified vacuole within macrophages. Carbon 122-128 Brown hair color Homo sapiens 67-71 23313636-7 2013 Decatenation assay revealed that naphthoquinone amide with 16-carbon atoms chain at 15 muM and 20 muM can completely inhibit hTopoIIalpha activity while at 10 muM the enzyme activity was moderately inhibited. Carbon 62-68 latexin Homo sapiens 87-90 23646545-2 2013 Field emission scanning electron microscopy, transmission electron microscopy, Raman and Fourier transformation infra-red spectroscopy indicate the carbon nanospheres are solid, bond hybridisation (sp2/sp3) and with many functional groups on their surfaces. Carbon 148-154 Sp2 transcription factor Homo sapiens 198-201 23220278-2 2013 By using density functional theory (DFT) method, the transfer mechanism of a 2-carbon fragment between a donor ketose X5P and an acceptor aldose R5P catalyzed by transketolase has been studied on simplified models. Carbon 79-85 transketolase Homo sapiens 162-175 23646545-2 2013 Field emission scanning electron microscopy, transmission electron microscopy, Raman and Fourier transformation infra-red spectroscopy indicate the carbon nanospheres are solid, bond hybridisation (sp2/sp3) and with many functional groups on their surfaces. Carbon 148-154 Sp3 transcription factor Homo sapiens 202-205 23273919-2 2013 In yeast, attenuation of signaling by these kinases following nitrogen and/or carbon limitation activates the protein kinase Rim15, which orchestrates the initiation of a reversible cellular quiescence program to ensure normal chronological life span. Carbon 78-84 protein kinase RIM15 Saccharomyces cerevisiae S288C 125-130 23160801-13 2013 The results of this study suggest that the aberrations in one-carbon metabolism appear to induce altered gene expression of EC-SOD, GSTP1, and BNIP3, and thus contribute to the increased oxidative stress and increased susceptibility to CAD. Carbon 62-68 superoxide dismutase 3 Homo sapiens 124-130 23160801-13 2013 The results of this study suggest that the aberrations in one-carbon metabolism appear to induce altered gene expression of EC-SOD, GSTP1, and BNIP3, and thus contribute to the increased oxidative stress and increased susceptibility to CAD. Carbon 62-68 BCL2 interacting protein 3 Homo sapiens 143-148 23099892-3 2013 Using the canonical Protein Kinase A (PKA) pathway as a test system, we show that changes in PKA activity can be measured in living cells as a modulation of the interaction between its regulatory (Bcy1) and catalytic (Tpk1 and Tpk2) subunits in response to changes in carbon metabolism, caffeine and methyl methanesulfonate (MMS) treatments and to modifications in the dosage of its enzymatic regulators, the phosphodiesterases. Carbon 268-274 cAMP-dependent protein kinase catalytic subunit TPK1 Saccharomyces cerevisiae S288C 218-222 23027424-0 2013 Spin-polarized semiconductors: tuning the electronic structure of graphene by introducing a regular pattern of sp3 carbons on the graphene plane. Carbon 115-122 Sp3 transcription factor Homo sapiens 111-114 23099892-3 2013 Using the canonical Protein Kinase A (PKA) pathway as a test system, we show that changes in PKA activity can be measured in living cells as a modulation of the interaction between its regulatory (Bcy1) and catalytic (Tpk1 and Tpk2) subunits in response to changes in carbon metabolism, caffeine and methyl methanesulfonate (MMS) treatments and to modifications in the dosage of its enzymatic regulators, the phosphodiesterases. Carbon 268-274 cAMP-dependent protein kinase catalytic subunit TPK2 Saccharomyces cerevisiae S288C 227-231 23203213-0 2013 Critical roles of key domains in complete adsorption of Abeta peptide on single-walled carbon nanotubes: insights with point mutations and MD simulations. Carbon 87-93 amyloid beta precursor protein Homo sapiens 56-61 23312317-2 2013 The amperometric biosensor, fabricated by immobilizing AChE on multi-walled carbon nanotubes-chitosan (MWCNTs-Chi) nanocomposites modified glassy carbon electrode, enjoyed high sensitivity owing to the excellent conductivity and favourable biocompatibility of MWCNTs-Chi nanocomposites. Carbon 76-82 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-59 23312317-2 2013 The amperometric biosensor, fabricated by immobilizing AChE on multi-walled carbon nanotubes-chitosan (MWCNTs-Chi) nanocomposites modified glassy carbon electrode, enjoyed high sensitivity owing to the excellent conductivity and favourable biocompatibility of MWCNTs-Chi nanocomposites. Carbon 146-152 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-59 23203213-2 2013 Based on atomistic molecular dynamics simulation studies we have recently reported that the full-length Abeta peptide, whose self-assembly is associated with Alzheimer"s disease, adsorbs rapidly on single-walled carbon nanotubes, thereby losing its natural propensity to collapse. Carbon 212-218 amyloid beta precursor protein Homo sapiens 104-109 23082993-2 2013 Both cellular and cell-free tests show that carbon associated to quartz completely inhibits the typical free radical generation of quartz dusts (through Fenton activity and homolytic cleavage of a C-H bond) and suppresses the oxidative stress and inflammation induced by quartz alone on MH-S murine macrophage cells (lipid peroxidation, nitric oxide release, and tumor necrosis factor-alpha synthesis). Carbon 44-50 tumor necrosis factor Mus musculus 363-390 22906713-2 2013 By combining laccase with catalase enzymes electrophoretically deposited by means of AC electric fields on multiple walled carbon nanotubes modified platinum black and, then stabilized by an outer layer of polypyrrole in the construction of GC/MWCNTs/Ptb/LAc-CAt/PPy biocathode, we can take advantage of the H(2)O(2) present in the solution or body tissue to increase the level of the dissolved O(2). Carbon 123-129 catalase Homo sapiens 26-34 23237229-2 2013 We prepared the lysine based Dap derivative l-Lys(Dap) in which the epsilon-NH(2) group was replaced by the tripod through conjugation to its alpha-carbon. Carbon 148-154 death-associated protein Mus musculus 29-32 23237229-2 2013 We prepared the lysine based Dap derivative l-Lys(Dap) in which the epsilon-NH(2) group was replaced by the tripod through conjugation to its alpha-carbon. Carbon 148-154 death-associated protein Mus musculus 50-53 22938840-0 2013 Multiwalled carbon nanotubes-ceramic electrode modified with substrate-selective imprinted polymer for ultra-trace detection of bovine serum albumin. Carbon 12-18 albumin Homo sapiens 135-148 23260679-3 2013 The detection area consists of aptamers immobilized on carbon nanotubes which specifically capture the vasopressin molecules in solution resulting in changes in conductivity across the sensor. Carbon 55-61 arginine vasopressin Homo sapiens 103-114 23187896-0 2013 Two viable three-dimensional carbon semiconductors with an entirely sp2 configuration. Carbon 29-35 Sp2 transcription factor Homo sapiens 68-71 23311980-3 2013 PEPCK offers a route, alternative to pyruvate kinase, for carbon skeletons to move between cytosolic glycolysis and mitochondrial Krebs cycle reactions. Carbon 58-64 Phosphoenolpyruvate carboxykinase 1 Drosophila melanogaster 0-5 23841325-2 2013 They can be associated with the already synthesized spongy carbon, consisting only of sp2 covalent carbon atoms, and the zeolites, periodic structures in the Euclidean space. Carbon 59-65 Sp2 transcription factor Homo sapiens 86-89 23245897-2 2013 The SOD-based biosensor was constructed by one-step ultrasonic electrodeposition of GNP-CS-IL composite onto glassy carbon electrode (GCE), followed by immobilization of SOD on the modified electrode. Carbon 116-122 superoxide dismutase 1 Homo sapiens 4-7 23267094-5 2013 In both embryos and adults, MTHFD1L catalyzes the last step in the flow of one-carbon units from mitochondria to cytoplasm, producing formate from 10-formyl-THF. Carbon 79-85 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like Mus musculus 28-35 23286607-1 2013 We study the growth mechanism of carbon molecules supplied by molecular beam epitaxy on fluoride substrates (MgF2, CaF2, and BaF2). Carbon 33-39 BANF family member 2 Homo sapiens 125-129 22985719-1 2013 Rubisco activase (Rca) is a chaperone-like protein of the AAA+ family, which uses mechano-chemical energy derived from ATP hydrolysis to release tightly bound inhibitors from the active site of the primary carbon fixing enzyme ribulose 1,5-bisphosphate oxygenase/carboxylase (Rubisco). Carbon 206-212 ribulose bisphosphate carboxylase/oxygenase activase 1, chloroplastic Nicotiana tabacum 0-16 23476317-0 2013 mu-Azido-kappa(2) N (1):N (1)-mu-chlorido-bis-[(2-chloro-3-dimethyl-amino-1-phenyl-prop-1-en-1-yl-kappa(2) C (1),N)palladium(II)] chloro-form monosolvate. Carbon 107-108 PROP paired-like homeobox 1 Homo sapiens 83-89 22851446-7 2013 The chapter discusses GAPDH as being a metabolic "switching station", diverting carbon flow appropriately. Carbon 80-86 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 22-27 22985719-1 2013 Rubisco activase (Rca) is a chaperone-like protein of the AAA+ family, which uses mechano-chemical energy derived from ATP hydrolysis to release tightly bound inhibitors from the active site of the primary carbon fixing enzyme ribulose 1,5-bisphosphate oxygenase/carboxylase (Rubisco). Carbon 206-212 ribulose bisphosphate carboxylase/oxygenase activase 1, chloroplastic Nicotiana tabacum 18-21 23629536-8 2013 The amount of adsorbed BSA increased in the following order: HA-pH 4.0, HA-pH 2.0, HA-40 C and HA-80 C. The amount of adsorbed LSZ on HA increased in the following order--HA-pH 2.0, HA-pH 4.0, HA-40 C and HA-80 C--with a corresponding decrease in the a/c intensity ratio. Carbon 89-90 lysozyme Homo sapiens 127-130 23629536-8 2013 The amount of adsorbed BSA increased in the following order: HA-pH 4.0, HA-pH 2.0, HA-40 C and HA-80 C. The amount of adsorbed LSZ on HA increased in the following order--HA-pH 2.0, HA-pH 4.0, HA-40 C and HA-80 C--with a corresponding decrease in the a/c intensity ratio. Carbon 29-30 lysozyme Homo sapiens 127-130 23626907-3 2013 In particular, myeloperoxidase (MPO), an enzyme expressed by inflammatory cells of animals including humans, catalyse the degradation of oxidized carbon nanomaterials. Carbon 146-152 myeloperoxidase Homo sapiens 15-30 23862620-5 2013 In the past half decade, deorphanization of several GPCRs has revealed that GPR40, GPR41, GPR43, GPR84 and GPR120 sense concentration of extracellular FFAs with various carbon chain lengths. Carbon 169-175 free fatty acid receptor 3 Homo sapiens 83-88 23862620-5 2013 In the past half decade, deorphanization of several GPCRs has revealed that GPR40, GPR41, GPR43, GPR84 and GPR120 sense concentration of extracellular FFAs with various carbon chain lengths. Carbon 169-175 free fatty acid receptor 2 Homo sapiens 90-95 24246730-5 2013 Introduction of bulky aromatic groups at the carbon linker, as in compounds 13 h-n, dramatically improved the selectivity profiles of hP2X3 when compared with mP2X1 and hP2X7 receptors. Carbon 45-51 purinergic receptor P2X 7 Homo sapiens 169-174 23626907-4 2013 While reactive intermediates generated by MPO efficiently degrade oxidized single-walled carbon nanotubes (o-SWCNTs); the exact mechanism of enzyme-catalysed biodegradation remains ambiguous. Carbon 89-95 myeloperoxidase Homo sapiens 42-45 24088267-0 2013 Multidrug resistance protein P-gp interaction with nanoparticles (fullerenes and carbon nanotube) to assess their drug delivery potential: a theoretical molecular docking study. Carbon 81-87 ATP binding cassette subfamily B member 1 Homo sapiens 29-33 24039418-0 2013 Nicotinamide-functionalized multiwalled carbon nanotubes increase insulin production in pancreatic beta cells via MIF pathway. Carbon 40-46 insulin Homo sapiens 66-73 24039418-3 2013 This study shows that administration of multiwalled carbon nanotubes (MWCNTs) functionalized with nicotinamide (NA-MWCNTs) leads to significant insulin production compared with individual administration of NA, MWCNTs, and a control solution. Carbon 52-58 insulin Homo sapiens 144-151 25464704-6 2013 SEM and BET results reveal that the carbons were mesoporous in nature. Carbon 36-43 putative DNA recombination protein Bet Escherichia coli 8-11 23209319-8 2013 First, Mac-1 facilitated poly I:C internalization through the activation of PI3K signaling and enhanced TLR3-dependent activation of IRF3 in macrophages. Carbon 32-33 integrin alpha M Mus musculus 7-12 23626907-3 2013 In particular, myeloperoxidase (MPO), an enzyme expressed by inflammatory cells of animals including humans, catalyse the degradation of oxidized carbon nanomaterials. Carbon 146-152 myeloperoxidase Homo sapiens 32-35 23238455-3 2013 The reason for this difference remains unknown, but we have previously found that serum proteins, such as bovine serum albumin (BSA), can contribute to in vitro formation of rounded M-C crystals. Carbon 184-185 albumin Homo sapiens 113-126 22672212-10 2013 While salivary gland dysfunction in poly(I:C)-treated IL-10(-/-) and EBI3(-/-) mice was comparable to wild-type mice, the IL-6(-/-) mice were more resistant, with only a 21% drop in function. Carbon 43-44 interleukin 10 Mus musculus 54-59 24199481-8 2013 The chemical shift of carbon in NCS2 group obtained from 13C NMR was found in range 198.86-203.53 ppm. Carbon 22-28 cytosolic thiouridylase subunit 2 Homo sapiens 32-36 24309588-3 2013 Here we report a facile approach to synthesize tunable graphene quantum dots from various types of coal, and establish that the unique coal structure has an advantage over pure sp2-carbon allotropes for producing quantum dots. Carbon 181-187 Sp2 transcription factor Homo sapiens 177-180 24309588-4 2013 The crystalline carbon within the coal structure is easier to oxidatively displace than when pure sp2-carbon structures are used, resulting in nanometre-sized graphene quantum dots with amorphous carbon addends on the edges. Carbon 16-22 Sp2 transcription factor Homo sapiens 98-101 24309588-4 2013 The crystalline carbon within the coal structure is easier to oxidatively displace than when pure sp2-carbon structures are used, resulting in nanometre-sized graphene quantum dots with amorphous carbon addends on the edges. Carbon 102-108 Sp2 transcription factor Homo sapiens 98-101 24309588-4 2013 The crystalline carbon within the coal structure is easier to oxidatively displace than when pure sp2-carbon structures are used, resulting in nanometre-sized graphene quantum dots with amorphous carbon addends on the edges. Carbon 102-108 Sp2 transcription factor Homo sapiens 98-101 23749575-0 2013 Single-walled carbon nanotube-mediated small interfering RNA delivery for gastrin-releasing peptide receptor silencing in human neuroblastoma. Carbon 14-20 gastrin releasing peptide receptor Homo sapiens 74-108 23749575-3 2013 Recently, we have demonstrated that single-walled carbon nanotube (SWNT)-mediated siRNA delivery can enhance the efficiency of siRNA-mediated gastrin-releasing peptide receptor (GRP-R) gene silencing by stabilizing siRNA while selectively targeting tumor tissues. Carbon 50-56 gastrin releasing peptide receptor Homo sapiens 142-176 23749575-3 2013 Recently, we have demonstrated that single-walled carbon nanotube (SWNT)-mediated siRNA delivery can enhance the efficiency of siRNA-mediated gastrin-releasing peptide receptor (GRP-R) gene silencing by stabilizing siRNA while selectively targeting tumor tissues. Carbon 50-56 gastrin releasing peptide receptor Homo sapiens 178-183 23535662-5 2013 Here, we find that yeast SCF (Skp1-Cdc53-F-box) Cullin-RING complexes are remodelled in a CAND1-dependent manner, when cells are switched from growth in fermentable to non-fermentable carbon sources. Carbon 184-190 cullin associated and neddylation dissociated 1 Canis lupus familiaris 90-95 23335616-4 2013 Transient overexpression of HAN also represses the expression of HAN and three other GATA3 family genes, HANL2 (HAN-LIKE 2), GNC (GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM-INVOLVED), and GNL (GNC-LIKE), forming a negative regulatory feedback loop. Carbon 155-161 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 28-31 22725103-0 2013 A diminution in ascorbate oxidase activity affects carbon allocation and improves yield in tomato under water deficit. Carbon 51-57 ascorbate oxidase Solanum lycopersicum 16-33 23335616-4 2013 Transient overexpression of HAN also represses the expression of HAN and three other GATA3 family genes, HANL2 (HAN-LIKE 2), GNC (GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM-INVOLVED), and GNL (GNC-LIKE), forming a negative regulatory feedback loop. Carbon 155-161 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 65-68 23424285-12 2013 Our results suggest a regulatory function of DLA2 in response to growth on reduced carbon energy sources. Carbon 83-89 uncharacterized protein Chlamydomonas reinhardtii 45-49 23459251-8 2013 These results suggest that cAMP is an important regulator of coral physiology, especially in response to light, acid/base disturbances and inorganic carbon levels. Carbon 149-155 cathelicidin antimicrobial peptide Homo sapiens 27-31 24084646-8 2013 Sucrose, particularly when fed exogenously, correlated well with TPS1 and TPPB gene expression, suggesting that these enzymes are involved in maintaining carbon flux through the pathway in relation to sucrose supply. Carbon 154-160 tryptase alpha/beta 1 Homo sapiens 65-69 23555027-10 2013 X-rays increased the CD235a(+) erythroid-related fraction, whereas carbon-ion beams increased the CD34(+)CD38(-) primitive cell fraction and the CD13(+)CD14(+/-)CD15(-) fraction. Carbon 67-73 CD34 molecule Homo sapiens 98-102 23342065-4 2013 In this part the mean exported POC:PON ratio of 9.7 (a:a) implies c. 40% higher carbon export compared to Redfield-based estimates. Carbon 80-86 paraoxonase 1 Homo sapiens 35-38 24305182-5 2013 Associated with this are disturbances to one-carbon metabolism, which can lead to epigenetic modifications to DNA and associated proteins in offspring that are both insulin resistant and hypertensive. Carbon 45-51 insulin Homo sapiens 165-172 23037143-0 2012 Turn-on fluorescence sensor based on single-walled-carbon-nanohorn-peptide complex for the detection of thrombin. Carbon 51-57 coagulation factor II, thrombin Homo sapiens 104-112 23171082-0 2012 Single-walled carbon nanotubes alter cytochrome c electron transfer and modulate mitochondrial function. Carbon 14-20 cytochrome c, somatic Homo sapiens 37-49 23084344-3 2012 Toda buffalo peripheral blood mononuclear cells (PBMC) produced significantly higher levels of IFN gamma and/or TNF alpha mRNAs in response to peptidoglycan, poly I:C, lipopolysaccharide, imiquimod and CpG. Carbon 52-53 interferon gamma Homo sapiens 95-104 23084344-3 2012 Toda buffalo peripheral blood mononuclear cells (PBMC) produced significantly higher levels of IFN gamma and/or TNF alpha mRNAs in response to peptidoglycan, poly I:C, lipopolysaccharide, imiquimod and CpG. Carbon 52-53 tumor necrosis factor Homo sapiens 112-121 23231781-7 2012 RESULTS: We found consistent positive associations between the following biomarkers and PM(2.5) chemical constituents across different models: TNF-alpha with secondary organic carbon, chloride, zinc, molybdenum and stannum; fibrinogen with magnesium, iron, titanium, cobalt and cadmium; PAI-1 with titanium, cobalt and manganese; t-PA with cadmium and selenium; vWF with aluminum. Carbon 176-182 tumor necrosis factor Homo sapiens 143-152 22982814-5 2012 18:2n-6 and its geometrical isomer (9E,12Z)18:2 were both mainly oxygenated at C-9 by COX-1, but the 9Z,12E isomer was mostly oxygenated at C-13. Carbon 79-80 cox1 Glycine max 86-91 23123153-2 2012 Methylenetetrahydrofolate reductase (Mthfr) plays a key role in folate metabolism by channeling one-carbon units between nucleotide synthesis and methylation reactions. Carbon 100-106 methylenetetrahydrofolate reductase Mus musculus 0-35 23123153-2 2012 Methylenetetrahydrofolate reductase (Mthfr) plays a key role in folate metabolism by channeling one-carbon units between nucleotide synthesis and methylation reactions. Carbon 100-106 methylenetetrahydrofolate reductase Mus musculus 37-42 23476299-4 2012 The P-N-P angles of 126.34 (11) and 125.98 (11) are larger than the four C-N-P bond angles. Carbon 74-75 purine nucleoside phosphorylase Homo sapiens 4-9 22982814-10 2012 In contrast, the more energetically demanding hydrogen abstractions of the allylic carbons of 20:1n-6 by COX-1 and 18:1n-9 by 8R-DOX were both accompanied by large D-KIE (>20). Carbon 83-90 cox1 Glycine max 105-110 22917965-0 2012 Micro-cubic monolithic carbon cryogel electrode for direct electron transfer reaction of fructose dehydrogenase. Carbon 23-29 aldehyde dehydrogenase 1 family member L1 Homo sapiens 89-111 22917965-1 2012 Micro-cubic monolithic carbon cryogel (CCG) electrode was fabricated for the electrochemical fructose dehydrogenase (FDH) reaction. Carbon 23-29 aldehyde dehydrogenase 1 family member L1 Homo sapiens 93-115 22917965-1 2012 Micro-cubic monolithic carbon cryogel (CCG) electrode was fabricated for the electrochemical fructose dehydrogenase (FDH) reaction. Carbon 23-29 aldehyde dehydrogenase 1 family member L1 Homo sapiens 117-120 23086900-3 2012 To develop a molecule that binds MPO, salicylhydroxamic acid (SHA), a substrate analog inhibitor of MPO with a KD=2 muM, was conjugated to a designed set of 42-residue polypeptide scaffolds via 9- and 11-carbon atom aliphatic spacers to form 20 different protein binder candidates, and their interactions with MPO were evaluated by surface plasmon resonance analysis. Carbon 204-210 myeloperoxidase Homo sapiens 33-36 22921904-6 2012 When stimulated with Poly (I:C) in vivo, attenuated accumulating in the liver and weaker expression of GranzymeB, TRAIL and FasL of NK1.1(+)CD3(-) cells were observed of IFN-gamma(-/-) mice. Carbon 29-30 TNF superfamily member 10 Homo sapiens 114-119 22921904-6 2012 When stimulated with Poly (I:C) in vivo, attenuated accumulating in the liver and weaker expression of GranzymeB, TRAIL and FasL of NK1.1(+)CD3(-) cells were observed of IFN-gamma(-/-) mice. Carbon 29-30 interferon gamma Homo sapiens 170-179 23095367-1 2012 Self-assembly of pristine multi-walled carbon nanotubes (CNTs) in aqueous dispersion using a protein, bovine serum albumin (BSA), has been demonstrated. Carbon 39-45 albumin Homo sapiens 109-122 23275579-7 2012 Genetic and physiological studies together with RNA sequencing and metabolite analysis of TOR-suppressed lines revealed that TOR regulates development and life span in Arabidopsis by restructuring cell growth, carbon and nitrogen metabolism, gene expression, and rRNA and protein synthesis. Carbon 210-216 target of rapamycin Arabidopsis thaliana 90-93 23275579-7 2012 Genetic and physiological studies together with RNA sequencing and metabolite analysis of TOR-suppressed lines revealed that TOR regulates development and life span in Arabidopsis by restructuring cell growth, carbon and nitrogen metabolism, gene expression, and rRNA and protein synthesis. Carbon 210-216 target of rapamycin Arabidopsis thaliana 125-128 23079127-8 2012 It suggests that the degradation of MC-LR is initiated via the attack of hydroxyl radicals on the conjugated carbon double bonds of Adda and on the benzene ring of Adda. Carbon 109-115 adducin 1 Homo sapiens 132-136 23126679-4 2012 Further down the catalytic cycles, HMS uses Fe(IV) O to perform hydroxylation of the benzylic carbon, whereas in HPPD, the reactive oxoferryl intermediate attacks the aromatic ring of HPA. Carbon 94-100 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 113-117 22725664-6 2012 A captodatively stabilized carbon-centered radical intermediate was spin trapped in the reaction of EdAG with hydroxyl radical. Carbon 27-33 hemogen Homo sapiens 100-104 23084051-1 2012 Here we designed a new electrochemical immunoassay protocol for determination of carcinoembryonic antigen (CEA) using nanoplatinum-enclosed gold nanocores (Pt@Au) as catalytically promoted nanolabels on the carbon nanospheres and graphene-modified immunosensor. Carbon 207-213 CEA cell adhesion molecule 3 Homo sapiens 81-105 23019566-1 2012 A bienzyme electrode for the determination of cholesterol was prepared by the co-immobilization of cholesterol oxidase and alkaline phosphatase (ALP) on the carbon nanotubes modified electrode surface. Carbon 157-163 alkaline phosphatase, placental Homo sapiens 123-143 23019566-1 2012 A bienzyme electrode for the determination of cholesterol was prepared by the co-immobilization of cholesterol oxidase and alkaline phosphatase (ALP) on the carbon nanotubes modified electrode surface. Carbon 157-163 alkaline phosphatase, placental Homo sapiens 145-148 23107134-0 2012 Layer by layer assembly of catalase and amine-terminated ionic liquid onto titanium nitride nanoparticles modified glassy carbon electrode: study of direct voltammetry and bioelectrocatalytic activity. Carbon 122-128 catalase Homo sapiens 27-35 23011577-1 2012 Sulfur-doped porous carbons hybridized with graphene (SPC@G) have been synthesized via a simple ionothermal method. Carbon 20-27 proline rich protein gene cluster Homo sapiens 54-57 22970432-1 2012 This paper reports for the first time the development of a large-scale SERS substrate from a popcorn-shaped gold nanoparticle-functionalized single walled carbon nanotubes hybrid thin film for the selective and highly sensitive detection of explosive TNT material at a 100 femtomolar (fM) level. Carbon 155-161 chromosome 16 open reading frame 82 Homo sapiens 251-254 22990419-3 2012 The molecular structure of [Mn(III)(6)Mn(III)](3+) is closely related to the already published [Mn(III)(6)M(c)](3+) complexes (M(c) = Cr(III), Fe(III), Co(III)). Carbon 108-110 mitochondrially encoded cytochrome c oxidase III Homo sapiens 31-34 22990419-3 2012 The molecular structure of [Mn(III)(6)Mn(III)](3+) is closely related to the already published [Mn(III)(6)M(c)](3+) complexes (M(c) = Cr(III), Fe(III), Co(III)). Carbon 108-110 mitochondrially encoded cytochrome c oxidase III Homo sapiens 41-44 22990419-3 2012 The molecular structure of [Mn(III)(6)Mn(III)](3+) is closely related to the already published [Mn(III)(6)M(c)](3+) complexes (M(c) = Cr(III), Fe(III), Co(III)). Carbon 108-110 mitochondrially encoded cytochrome c oxidase III Homo sapiens 41-44 22990419-3 2012 The molecular structure of [Mn(III)(6)Mn(III)](3+) is closely related to the already published [Mn(III)(6)M(c)](3+) complexes (M(c) = Cr(III), Fe(III), Co(III)). Carbon 108-110 mitochondrially encoded cytochrome c oxidase III Homo sapiens 41-44 22990419-3 2012 The molecular structure of [Mn(III)(6)Mn(III)](3+) is closely related to the already published [Mn(III)(6)M(c)](3+) complexes (M(c) = Cr(III), Fe(III), Co(III)). Carbon 108-110 mitochondrially encoded cytochrome c oxidase III Homo sapiens 41-44 23084051-1 2012 Here we designed a new electrochemical immunoassay protocol for determination of carcinoembryonic antigen (CEA) using nanoplatinum-enclosed gold nanocores (Pt@Au) as catalytically promoted nanolabels on the carbon nanospheres and graphene-modified immunosensor. Carbon 207-213 CEA cell adhesion molecule 3 Homo sapiens 107-110 23141325-4 2012 The Cu,ZnSOD (SOD1) immobilized on the carbon nanotubes in polypyrrole modified platinum electrode was used as the NO biosensor. Carbon 39-45 superoxide dismutase 1 Homo sapiens 14-18 23387078-1 2012 Methionine synthase (MS, EC2.1.1.13), a key enzyme in the folate metabolism area catalyzing methyl transfer from N5-methyltetrahydrofolate to homocysteine to give tetrahydrofolate and methionine, takes a core position in folate cycle, one-carbon-unit transfer and sculpture amino acid pathways. Carbon 239-245 5-methyltetrahydrofolate-homocysteine methyltransferase Rattus norvegicus 0-19 22475642-0 2012 Prostaglandin E2 suppresses poly I: C-stimulated cytokine production via EP2 and EP3 in immortalized human corneal epithelial cells. Carbon 36-37 prostaglandin E receptor 3 Homo sapiens 81-84 22475642-7 2012 The EP2 agonist significantly suppressed the polyI:C-induced expression of CCL5 (P < 0.005), CXCL10 (P < 0.0005), and CXCL11 (P < 0.05) but not of CCL20 and IL-6. Carbon 51-52 interleukin 6 Homo sapiens 166-170 22796648-4 2012 Soil DDT, HCB, PCB and PBDE concentrations were strongly influenced by soil organic carbon content. Carbon 84-90 pyruvate carboxylase Homo sapiens 15-18 22930732-0 2012 The Medicago truncatula sucrose transporter family: characterization and implication of key members in carbon partitioning towards arbuscular mycorrhizal fungi. Carbon 103-109 sucrose transport protein SUC4 Medicago truncatula 24-43 23243478-3 2012 Here we performed a comprehensive spectroscopic study to probe the interactions between bovine serum albumin (BSA) and carbon-based nanostructures of graphene and single-walled carbon nanotubes (SWNTs). Carbon 119-125 albumin Homo sapiens 95-108 23243478-3 2012 Here we performed a comprehensive spectroscopic study to probe the interactions between bovine serum albumin (BSA) and carbon-based nanostructures of graphene and single-walled carbon nanotubes (SWNTs). Carbon 177-183 albumin Homo sapiens 95-108 22975186-0 2012 Simultaneous trace-levels determination of Hg(II) and Pb(II) ions in various samples using a modified carbon paste electrode based on multi-walled carbon nanotubes and a new synthesized Schiff base. Carbon 102-108 submaxillary gland androgen regulated protein 3B Homo sapiens 54-60 22990172-0 2012 A physics/circuit-based switching model for carbon-based resistive memory with sp2/sp3 cluster conversion. Carbon 44-50 Sp2 transcription factor Homo sapiens 79-82 22990172-0 2012 A physics/circuit-based switching model for carbon-based resistive memory with sp2/sp3 cluster conversion. Carbon 44-50 Sp3 transcription factor Homo sapiens 83-86 22990172-1 2012 The switching mechanism in carbon-based resistive-switching random access memory is modelled using a percolation approach built on the low-temperature transition between phases sp(3) (diamond-like and high-resistive state) and sp(2) (graphite-like and low-resistive state) for a matrix of carbon clusters in a diamond-like carbon film. Carbon 27-33 Sp3 transcription factor Homo sapiens 177-182 22990172-1 2012 The switching mechanism in carbon-based resistive-switching random access memory is modelled using a percolation approach built on the low-temperature transition between phases sp(3) (diamond-like and high-resistive state) and sp(2) (graphite-like and low-resistive state) for a matrix of carbon clusters in a diamond-like carbon film. Carbon 27-33 Sp2 transcription factor Homo sapiens 227-232 22975186-1 2012 A modified carbon paste electrode based on multi-walled carbon nanotubes (MWCNTs) and 3-(4-methoxybenzylideneamino)-2-thioxothiazolodin-4-one as a new synthesized Schiff base was constructed for the simultaneous determination of trace amounts of Hg(II) and Pb(II) by square wave anodic stripping voltammetry. Carbon 11-17 submaxillary gland androgen regulated protein 3B Homo sapiens 257-263 22975187-1 2012 A novel and sensitive sandwich-type electrochemiluminescence (ECL) immunosensor was fabricated on a glassy carbon electrode (GCE) for ultra trace levels of alpha-fetoprotein (AFP) based on sandwich immunoreaction strategy by enrichment using magnetic capture probes and quantum dots coated with Au shell (CdS-Au) as the signal tag. Carbon 107-113 alpha fetoprotein Homo sapiens 156-173 23021811-0 2012 A rational design of the multiwalled carbon nanotube-7,7,8,8-tetracyanoquinodimethan sensor for sensitive detection of acetylcholinesterase inhibitors. Carbon 37-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 119-139 22975187-1 2012 A novel and sensitive sandwich-type electrochemiluminescence (ECL) immunosensor was fabricated on a glassy carbon electrode (GCE) for ultra trace levels of alpha-fetoprotein (AFP) based on sandwich immunoreaction strategy by enrichment using magnetic capture probes and quantum dots coated with Au shell (CdS-Au) as the signal tag. Carbon 107-113 alpha fetoprotein Homo sapiens 175-178 22818986-0 2012 The attenuation of restenosis following arterial gene transfer using carbon nanotube coated stent incorporating TAT/DNA(Ang1+Vegf) nanoparticles. Carbon 69-75 angiopoietin 1 Canis lupus familiaris 120-124 23021811-1 2012 A new, simple and effective amperometric acetylcholinesterase biosensor was developed using screen-printed carbon electrodes modified with carbon nanotubes (MWCNTs)-7,7,8,8-tetracyanoquinodimethane (TCNQ). Carbon 107-113 acetylcholinesterase (Cartwright blood group) Homo sapiens 41-61 23021811-1 2012 A new, simple and effective amperometric acetylcholinesterase biosensor was developed using screen-printed carbon electrodes modified with carbon nanotubes (MWCNTs)-7,7,8,8-tetracyanoquinodimethane (TCNQ). Carbon 139-145 acetylcholinesterase (Cartwright blood group) Homo sapiens 41-61 23125582-1 2012 In the title compound, [Co(CH(3)CO(2))(C(18)H(24)N(6))]PF(6), the Co(II) atom is penta-coordinated in a distorted trigonal-bipyramidal geometry by four N atoms from a tripodal ligand and one O atom from a monodentate acetate ligand. Carbon 39-41 mitochondrially encoded cytochrome c oxidase II Homo sapiens 66-72 22837356-9 2012 By contrast, silencing of WRINKLED1 expression resulted in increased fiber length but reduced oil seed content, suggesting the possibility to increase fiber length by repartitioning carbon flow. Carbon 182-188 ethylene-responsive transcription factor WRI1-like Gossypium hirsutum 26-35 23234003-2 2012 Results showed that ozone could be thoroughly decomposed (removal rate was maintaining 100% all along the process studied) for 5 h under the condition of O3 12.89 mg x min(-1), 18 mm diameter glass tube was stuffed by activated carbon (made from coal, 2.0-2.5 mm diameter). Carbon 228-234 CD59 molecule (CD59 blood group) Homo sapiens 168-174 22750548-3 2012 We tested the hyphothesis that poly(I:C) and anti-CD28 mAb costimulation differ in their effect on the CD4 T cell immune response. Carbon 38-39 CD4 molecule Homo sapiens 103-106 22789758-1 2012 Simultaneous removal of carbon and nutrients (CNP) in a single bioreactor is highly significant for energy consumption and control of reactor volume. Carbon 24-30 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 46-49 23130796-1 2012 The new JET ITER-like wall (made of beryllium and tungsten) is more fragile than the former carbon fiber composite wall and requires active protection to prevent excessive heat loads on the plasma facing components (PFC). Carbon 104-110 F-box and leucine rich repeat protein 15 Homo sapiens 8-11 22690903-5 2012 Only lipopolysaccharide (LPS), poly(I:C), Pam3CSK4 and MALP-2 could induce the production of IL-6, IL-8 and MCP-1 by adipocytes. Carbon 38-39 interleukin 6 Homo sapiens 93-97 22690903-5 2012 Only lipopolysaccharide (LPS), poly(I:C), Pam3CSK4 and MALP-2 could induce the production of IL-6, IL-8 and MCP-1 by adipocytes. Carbon 38-39 C-X-C motif chemokine ligand 8 Homo sapiens 99-103 23093808-0 2012 Formation and cell translocation of carbon nanotube-fibrinogen protein corona. Carbon 36-42 fibrinogen beta chain Homo sapiens 52-62 23093808-1 2012 The binding of plasma fibrinogen with both single-walled and multi-walled carbon nanotubes (SWNTs and MWNTs) has been examined. Carbon 74-80 fibrinogen beta chain Homo sapiens 22-32 22790609-2 2012 We have summarized the relevant data that have so far been published, presenting them in a graphical form, i.e., as biodegradation pathways including B12-dependent isomerization and desaturation that lead to the degradation of pivalic acid and similar compounds to products with other than quaternary carbon atoms, i.e., compounds whose catabolism is well known. Carbon 301-307 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 150-153 22967530-1 2012 An adsorptive stripping voltammetric (AdSV) method is presented for the simultaneous determination of Pb(II) and Cd(II) at trace levels in natural waters, based on metal complexation with pyrogallol red (PR) and subsequent adsorptive deposition on a Nafion-mercury coated glassy carbon electrode (NHgFE). Carbon 279-285 submaxillary gland androgen regulated protein 3B Homo sapiens 102-108 22904303-4 2012 Polyinosinic-polycytidylic acid [Poly (I:C)], a dsRNA receptor ligand, activates Rac via its guanine nucleotide exchange factor Tiam; this leads to the activation of cytokine genes and, paradoxically, downregulation of the Tipe2 gene. Carbon 41-43 thymoma viral proto-oncogene 1 Mus musculus 81-84 22885179-9 2012 This strongly suggests that iNOS activity, but not that of ARG1, is related to an enhanced central carbon metabolism and a high bioenergetic status. Carbon 99-105 nitric oxide synthase 2, inducible Mus musculus 28-32 22889055-3 2012 Relative to peridinin, S-1- and S-2-peridinin have their lactone rings two and four carbons more toward the center of the pi-electron system of conjugated carbon-carbon double bonds, respectively. Carbon 84-91 proteasome 26S subunit, non-ATPase 1 Homo sapiens 23-27 22889055-3 2012 Relative to peridinin, S-1- and S-2-peridinin have their lactone rings two and four carbons more toward the center of the pi-electron system of conjugated carbon-carbon double bonds, respectively. Carbon 84-90 proteasome 26S subunit, non-ATPase 1 Homo sapiens 23-27 22889055-3 2012 Relative to peridinin, S-1- and S-2-peridinin have their lactone rings two and four carbons more toward the center of the pi-electron system of conjugated carbon-carbon double bonds, respectively. Carbon 155-161 proteasome 26S subunit, non-ATPase 1 Homo sapiens 23-27 22659048-5 2012 Here we show that expression of GPX1 was induced in medium containing oleic acid as a carbon source in an Msn2/Msn4-dependent manner. Carbon 86-92 stress-responsive transcriptional activator MSN4 Saccharomyces cerevisiae S288C 111-115 22740285-0 2012 sp3 -linked amorphous carbon with sulfonic acid groups as a heterogeneous acid catalyst. Carbon 22-28 Sp3 transcription factor Homo sapiens 0-3 22437968-7 2012 The rate of Ery decolorization almost duplicated in the presence of commercial AC (0.1 g L-1 AC0). Carbon 79-81 immunoglobulin kappa variable 1-16 Homo sapiens 89-92 22740285-2 2012 Sulfonation of partially carbonized PVC produces amorphous carbon consisting of small SO3H-bearing carbon sheets linked by sp3 -based aliphatic hydrocarbons. Carbon 25-31 Sp3 transcription factor Homo sapiens 123-126 22740285-2 2012 Sulfonation of partially carbonized PVC produces amorphous carbon consisting of small SO3H-bearing carbon sheets linked by sp3 -based aliphatic hydrocarbons. Carbon 59-65 Sp3 transcription factor Homo sapiens 123-126 23243862-0 2012 [Relationship between dissolved organic carbon and DBP in the Pearl River water]. Carbon 40-46 D-box binding PAR bZIP transcription factor Homo sapiens 51-54 22540321-12 2012 We propose that SLO2 is required for carbon energy balance in Arabidopsis by maintaining the abundance and/or activity of complexes I, III, and IV of the mitochondrial electron transport chain. Carbon 37-43 Pentatricopeptide repeat (PPR) superfamily protein Arabidopsis thaliana 16-20 22859760-1 2012 Pyruvate carboxylase (PC) catalyzes the rate-limiting step in gluconeogenesis from lactate and is a determinant of tricarboxylic acid cycle carbon flux. Carbon 140-146 pyruvate carboxylase Bos taurus 0-20 22859760-1 2012 Pyruvate carboxylase (PC) catalyzes the rate-limiting step in gluconeogenesis from lactate and is a determinant of tricarboxylic acid cycle carbon flux. Carbon 140-146 pyruvate carboxylase Bos taurus 22-24 22665368-8 2012 These studies suggest that SNPs in CBS and MTRR have sex-specific associations with aberrant methylation in the lung epithelium of smokers that could be mediated by the affected one-carbon metabolism and transsulfuration in the cells. Carbon 182-188 cystathionine beta-synthase Homo sapiens 35-38 22764083-3 2012 The reaction occurs through a single-electron transfer from the doublet Co(II) catalyst to the epoxide and forms a doublet Co(III)-carbon radical intermediate. Carbon 131-137 mitochondrially encoded cytochrome c oxidase II Homo sapiens 72-78 22480862-3 2012 Cytochrome P450 3A4 was immobilized on glassy carbon electrodes in the presence of a cationic polyelectrolyte, PDDA (poly(diallyldimethylammonium chloride)). Carbon 46-52 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 0-19 22798479-6 2012 iNOS methylation was decreased after acute exposure to both black carbon and PM(2.5). Carbon 66-72 nitric oxide synthase 2 Homo sapiens 0-4 22798479-7 2012 A 1-mug/m(3) increase in exposure to black carbon in the 4 hours preceding the clinical examination was associated with a 0.9% decrease in 5-methylcytosine (95% CI: 0.4, 1.4) in iNOS, and a 10-mug/m(3) increase in exposure to PM(2.5) was associated with a 0.6% decrease in 5-methylcytosine (95% CI: 0.03, 1.1) in iNOS. Carbon 43-49 nitric oxide synthase 2 Homo sapiens 178-182 22798479-7 2012 A 1-mug/m(3) increase in exposure to black carbon in the 4 hours preceding the clinical examination was associated with a 0.9% decrease in 5-methylcytosine (95% CI: 0.4, 1.4) in iNOS, and a 10-mug/m(3) increase in exposure to PM(2.5) was associated with a 0.6% decrease in 5-methylcytosine (95% CI: 0.03, 1.1) in iNOS. Carbon 43-49 nitric oxide synthase 2 Homo sapiens 313-317 22665368-8 2012 These studies suggest that SNPs in CBS and MTRR have sex-specific associations with aberrant methylation in the lung epithelium of smokers that could be mediated by the affected one-carbon metabolism and transsulfuration in the cells. Carbon 182-188 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 43-47 22535206-6 2012 Cancer cells, as opposed to near-normal MCF-10A cells, exhibited significantly increased expression of key energy metabolic pathway enzymes (FBP1, IDH2, and G6PD) that are known to redirect cellular metabolism and increase carbon flux through the pentose phosphate pathway. Carbon 223-229 isocitrate dehydrogenase (NADP(+)) 2 Homo sapiens 147-151 22100755-0 2012 Double-walled carbon nanotubes trigger IL-1beta release in human monocytes through Nlrp3 inflammasome activation. Carbon 14-20 interleukin 1 beta Homo sapiens 39-47 22849850-10 2012 25-HC significantly potentiated IL-8 release in poly(I:C)-treated cells and the augmentation was inhibited by CAPE, BAY 11-7085, and SC-514. Carbon 55-57 C-X-C motif chemokine ligand 8 Homo sapiens 32-36 22100755-0 2012 Double-walled carbon nanotubes trigger IL-1beta release in human monocytes through Nlrp3 inflammasome activation. Carbon 14-20 NLR family pyrin domain containing 3 Homo sapiens 83-88 22866581-3 2012 The sulfur-impregnated activated carbons were examined for the adsorptive capacity of gas-phase mercuric chloride (HgC1) by thermogravimetric analysis (TGA). Carbon 33-40 olfactomedin 4 Homo sapiens 115-119 22817944-0 2012 Flow injection catalase activity measurement based on gold nanoparticles/carbon nanotubes modified glassy carbon electrode. Carbon 73-79 catalase Rattus norvegicus 15-23 22817944-0 2012 Flow injection catalase activity measurement based on gold nanoparticles/carbon nanotubes modified glassy carbon electrode. Carbon 106-112 catalase Rattus norvegicus 15-23 22817944-1 2012 Amperometric flow injection method of hydrogen peroxide analysis was developed based on catalase enzyme (CAT) immobilization on a glassy carbon electrode (GC) modified with electrochemically deposited gold nanoparticles on a multiwalled carbon nanotubes/chitosan film. Carbon 137-143 catalase Rattus norvegicus 88-103 22817944-1 2012 Amperometric flow injection method of hydrogen peroxide analysis was developed based on catalase enzyme (CAT) immobilization on a glassy carbon electrode (GC) modified with electrochemically deposited gold nanoparticles on a multiwalled carbon nanotubes/chitosan film. Carbon 137-143 catalase Rattus norvegicus 105-108 22817944-1 2012 Amperometric flow injection method of hydrogen peroxide analysis was developed based on catalase enzyme (CAT) immobilization on a glassy carbon electrode (GC) modified with electrochemically deposited gold nanoparticles on a multiwalled carbon nanotubes/chitosan film. Carbon 237-243 catalase Rattus norvegicus 88-103 22817944-1 2012 Amperometric flow injection method of hydrogen peroxide analysis was developed based on catalase enzyme (CAT) immobilization on a glassy carbon electrode (GC) modified with electrochemically deposited gold nanoparticles on a multiwalled carbon nanotubes/chitosan film. Carbon 237-243 catalase Rattus norvegicus 105-108 23030177-4 2012 This latter phase is better described as a short interlayered carbon phase with buckled sp2-sp3 layers with possible interlayer bonding. Carbon 62-68 Sp2 transcription factor Homo sapiens 88-91 23030177-4 2012 This latter phase is better described as a short interlayered carbon phase with buckled sp2-sp3 layers with possible interlayer bonding. Carbon 62-68 Sp3 transcription factor Homo sapiens 92-95 22697467-0 2012 Carbon-based leaving group in substitution reactions: functionalization of sp3-hybridized quaternary and tertiary benzylic carbon centers. Carbon 0-6 Sp3 transcription factor Homo sapiens 75-78 22697467-0 2012 Carbon-based leaving group in substitution reactions: functionalization of sp3-hybridized quaternary and tertiary benzylic carbon centers. Carbon 123-129 Sp3 transcription factor Homo sapiens 75-78 22988612-2 2012 In the absence of any textile preparation chemical, NP-10 degradation was complete in 15 min (rate coefficient: 0.22 min(-1)) accompanied by 78% chemical oxygen demand (COD) (rate coefficient: 0.026 min(-1)) and 57% total organic carbon (TOC) (rate coefficient: 0.014 min(-1)) removals achieved after 60 min photochemical treatment. Carbon 230-236 nuclear receptor subfamily 4 group A member 1 Homo sapiens 52-57 22706976-0 2012 Stereocontrolled synthesis of carbocyclic compounds with a quaternary carbon atom based on SN2" alkylation of gamma,delta-epoxy-alpha,beta-unsaturated ketones. Carbon 70-76 solute carrier family 38 member 5 Homo sapiens 91-94 22652008-8 2012 It was also found that organic carbon was an important factor for PAHs and high chlorinated PCB retention in soils. Carbon 31-37 pyruvate carboxylase Homo sapiens 92-95 22803542-0 2012 Phase conversion from graphite toward a simple monoclinic sp3-carbon allotrope. Carbon 62-68 Sp3 transcription factor Homo sapiens 58-61 22687276-4 2012 Growth factor signaling mediated by the PI3K/Akt pathway plays a major role in regulating the cellular uptake of glucose, as well as the incorporation of this glucose carbon into lipids for membrane synthesis. Carbon 167-173 AKT serine/threonine kinase 1 Homo sapiens 45-48 22560315-4 2012 For the derivatives tested, the one that contains a C(16) amide carbon chain is the most active with an IC(50) of 17.0 muM for A375 and 5.8 muM for MCF7. Carbon 64-70 latexin Homo sapiens 119-122 22560315-4 2012 For the derivatives tested, the one that contains a C(16) amide carbon chain is the most active with an IC(50) of 17.0 muM for A375 and 5.8 muM for MCF7. Carbon 64-70 latexin Homo sapiens 140-143 22625429-6 2012 Furthermore, we report that a unique and previously uncharacterized 14-3-3 family protein in P. pastoris complements Saccharomyces cerevisiae 14-3-3 functions and interacts with Mxr1 through its 14-3-3 binding region via phosphorylation of Ser215 in a carbon source-dependent manner. Carbon 252-258 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 178-182 22625429-2 2012 Expression of Mxr1-dependent genes is regulated in response to various carbon sources by an unknown mechanism. Carbon 71-77 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 14-18 22372824-5 2012 Therefore, we have developed a multiplexed, implantable immunosensor to detect amyloid beta (Abeta) isoforms using triple barrel carbon fiber microelectrodes as the sensor platform. Carbon 129-135 amyloid beta precursor protein Homo sapiens 79-91 22372824-5 2012 Therefore, we have developed a multiplexed, implantable immunosensor to detect amyloid beta (Abeta) isoforms using triple barrel carbon fiber microelectrodes as the sensor platform. Carbon 129-135 amyloid beta precursor protein Homo sapiens 93-98 22625429-7 2012 Indeed, our in vivo results suggest a carbon source-dependent regulation of expression of Mxr1-activated genes by 14-3-3 in P. pastoris. Carbon 38-44 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 90-94 22625429-9 2012 We provide the first molecular explanation of carbon source-mediated regulation of Mxr1 activity, whose mechanism involves a post-DNA binding role of 14-3-3. Carbon 46-52 peptide-methionine-S-sulfoxide reductase Saccharomyces cerevisiae S288C 83-87 22575126-1 2012 We developed a novel detection method for osteopontin (OPN), a new biomarker for prostate cancer, by attaching a genetically engineered single-chain variable fragment (scFv) protein with high binding affinity for OPN to a carbon nanotube field-effect transistor (NT-FET). Carbon 222-228 immunglobulin heavy chain variable region Homo sapiens 168-172 22413742-8 2012 Our results indicate that expression of AtALMT1(P)::AtMATE not only significantly increased Al resistance of the transgenic plants, but also enhanced carbon-use efficiency for Al resistance. Carbon 150-156 aluminum-activated malate transporter 1 Arabidopsis thaliana 40-47 22697787-4 2012 The next step is nucleophilic attack on the carbonyl carbon of EPX by the negatively charged Thr1-O(gamma) atom, followed by a proton transfer from Thr1-N(z) to the carbonyl oxygen of EPX (third step). Carbon 44-50 thyroid hormone receptor beta Homo sapiens 93-97 22697787-4 2012 The next step is nucleophilic attack on the carbonyl carbon of EPX by the negatively charged Thr1-O(gamma) atom, followed by a proton transfer from Thr1-N(z) to the carbonyl oxygen of EPX (third step). Carbon 44-50 thyroid hormone receptor beta Homo sapiens 148-152 22697787-5 2012 Then, Thr1-N(z) attacks on the carbon of the epoxide group of EPX, accompanied by the epoxide ring-opening (S(N)2 nucleophilic substitution) such that a zwitterionic morpholino ring is formed between residue Thr1 and EPX. Carbon 31-37 thyroid hormone receptor beta Homo sapiens 6-10 22697787-5 2012 Then, Thr1-N(z) attacks on the carbon of the epoxide group of EPX, accompanied by the epoxide ring-opening (S(N)2 nucleophilic substitution) such that a zwitterionic morpholino ring is formed between residue Thr1 and EPX. Carbon 31-37 thyroid hormone receptor beta Homo sapiens 208-212 22575126-7 2012 On the basis of these observations, the detection mechanism is attributed to changes in scattering at scFv protein-occupied defect sites on the carbon nanotube sidewall. Carbon 144-150 immunglobulin heavy chain variable region Homo sapiens 102-106 22428663-0 2012 Cell cycle regulation by carboxylated multiwalled carbon nanotubes through p53-independent induction of p21 under the control of the BMP signaling pathway. Carbon 50-56 tumor protein p53 Homo sapiens 75-78 22675123-10 2012 The absence of such a carbon-enriched water mass in the North Atlantic during MIS 5 can explain the smaller amount of carbon released to the atmosphere after the Antarctic temperature maximum and, hence, the shorter lag. Carbon 22-28 minichromosome maintenance complex component 6 Homo sapiens 78-83 22428663-1 2012 This report describes how carboxylated multiwalled carbon nanotubes (MWCNTs) induce p53-independent p21 expression and cell cycle arrest. Carbon 51-57 tumor protein p53 Homo sapiens 84-87 22481162-0 2012 The Arabidopsis ubiquitin ligases ATL31 and ATL6 control the defense response as well as the carbon/nitrogen response. Carbon 93-99 RING/U-box superfamily protein Arabidopsis thaliana 44-48 22709825-13 2012 Ethanol pretreatment potentiated poly I:C-induced brain TNFalpha (345%), IL-1beta (331%), IL-6 (255%), and MCP-1(190%). Carbon 40-41 interleukin 6 Mus musculus 90-94 22709825-13 2012 Ethanol pretreatment potentiated poly I:C-induced brain TNFalpha (345%), IL-1beta (331%), IL-6 (255%), and MCP-1(190%). Carbon 40-41 mast cell protease 1 Mus musculus 107-112 22514274-3 2012 In the dark oxidized CP12 forms an inactive supramolecular complex with glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and phosphoribulokinase, two enzymes of the carbon assimilation cycle. Carbon 165-171 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 72-112 22647071-0 2012 Access to C(sp3)-C(sp2) and C(sp2)-C(sp2) bond formation via sequential intermolecular carbopalladation of multiple carbon-carbon bonds. Carbon 116-122 Sp2 transcription factor Homo sapiens 17-22 22647071-0 2012 Access to C(sp3)-C(sp2) and C(sp2)-C(sp2) bond formation via sequential intermolecular carbopalladation of multiple carbon-carbon bonds. Carbon 116-122 Sp2 transcription factor Homo sapiens 28-33 22647071-0 2012 Access to C(sp3)-C(sp2) and C(sp2)-C(sp2) bond formation via sequential intermolecular carbopalladation of multiple carbon-carbon bonds. Carbon 116-122 Sp2 transcription factor Homo sapiens 28-33 22647071-0 2012 Access to C(sp3)-C(sp2) and C(sp2)-C(sp2) bond formation via sequential intermolecular carbopalladation of multiple carbon-carbon bonds. Carbon 123-129 Sp2 transcription factor Homo sapiens 17-22 22647071-0 2012 Access to C(sp3)-C(sp2) and C(sp2)-C(sp2) bond formation via sequential intermolecular carbopalladation of multiple carbon-carbon bonds. Carbon 123-129 Sp2 transcription factor Homo sapiens 28-33 22647071-0 2012 Access to C(sp3)-C(sp2) and C(sp2)-C(sp2) bond formation via sequential intermolecular carbopalladation of multiple carbon-carbon bonds. Carbon 123-129 Sp2 transcription factor Homo sapiens 28-33 22533690-5 2012 Land could become a large net carbon sink of about 178 Pg C over the 21st century with price incentives in the Energy+Land scenario. Carbon 30-36 progastricsin Homo sapiens 55-59 22655860-2 2012 It is found that in amorphous and carbon films with nanometer-sized sp2 clusters, the emission does not depend on the film thickness. Carbon 34-40 Sp2 transcription factor Homo sapiens 68-71 22514274-3 2012 In the dark oxidized CP12 forms an inactive supramolecular complex with glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and phosphoribulokinase, two enzymes of the carbon assimilation cycle. Carbon 165-171 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 114-119 22573031-0 2012 Cu(II)-catalyzed C-H (SP3) oxidation and C-N cleavage: base-switched methylenation and formylation using tetramethylethylenediamine as a carbon source. Carbon 137-143 Sp3 transcription factor Homo sapiens 0-25 22503784-10 2012 By using inhibitors of PLC activation, U73122, and the inositol 1,4,5-triphosphate (IP(3)) receptor, xestospongin-C, we demonstrated that ET-1 induces ER stress via the PLC-IP(3) pathway. Carbon 25-26 endothelin 1 Homo sapiens 138-142 22404155-6 2012 Treatment with a PARP inhibitor enhanced the cytotoxic effect of gamma-irradiation and LET 13 and LET 70 carbon-ion irradiation. Carbon 105-111 poly(ADP-ribose) polymerase 1 Homo sapiens 17-21 22404155-8 2012 Prolonged and increased levels of gamma-H2AX were observed both after gamma-irradiation and carbon-ion irradiation in the presence of the PARP inhibitor. Carbon 92-98 poly(ADP-ribose) polymerase 1 Homo sapiens 138-142 22404155-10 2012 PARP inhibitor treatment induced S phase arrest and enhanced subsequent G2/M arrest both after gamma-irradiation and carbon-ion irradiation. Carbon 117-123 poly(ADP-ribose) polymerase 1 Homo sapiens 0-4 22404155-11 2012 These results suggest that the induction of S phase arrest through an enhanced DDR and a local delay in DNA double strand break processing by PARP inhibition caused sensitization to gamma-irradiation and carbon-ion irradiation. Carbon 204-210 poly(ADP-ribose) polymerase 1 Homo sapiens 142-146 22076974-5 2012 GCPII and folate depletion interact within the one-carbon metabolic pathway and/or of modulate the glutamatergic system. Carbon 51-57 folate hydrolase 1 Mus musculus 0-5 31080327-3 2012 The test coils were wound with 95-m long unreacted, C (carbon)-doped MgB2 multifilament wire, sintered at 700 C for 90 min. Carbon 55-61 secretoglobin family 2A member 1 Homo sapiens 69-73 22461194-0 2012 Colloidal carbon stimulation of Kupffer cells triggers Nrf2 activation in the isolated perfused rat liver. Carbon 10-16 NFE2 like bZIP transcription factor 2 Rattus norvegicus 55-59 22461194-1 2012 Activation of transcription factor Nrf2 was investigated in the isolated perfused rat liver infused with 0.5 mg of colloidal carbon (CC)/ml for 5-15 min to stimulated Kupffer cell function. Carbon 125-131 NFE2 like bZIP transcription factor 2 Rattus norvegicus 35-39 22608421-0 2012 Dynamic layer-by-layer self-assembly of multi-walled carbon nanotubes on quartz wool for on-line separation of lysozyme in egg white. Carbon 53-59 lysozyme Homo sapiens 111-119 22231731-14 2012 Iloprost suppressed poly I:C-induced mitogen-activated protein kinase (MAPK) phospho-p38 and phospho-activating transcription factor (ATF)2 expression. Carbon 27-28 mitogen-activated protein kinase 14 Homo sapiens 85-88 25585713-2 2012 A single use, disposable biosensor prototype, composed of catalytic iridium nano-particles dispersed on carbon paste, was developed to detect enzymatically-produced H2O2 in AST-mediated reactions. Carbon 104-110 solute carrier family 17 member 5 Homo sapiens 173-176 22444512-2 2012 A novel stable gold nanoparticle (AuNP)-modified glassy carbon (GC) electrode interface (GC-Ph-AuNP)-based biosensor for detecting carcinoembryonic antigen (CEA) was developed. Carbon 56-62 CEA cell adhesion molecule 3 Homo sapiens 131-155 22444512-2 2012 A novel stable gold nanoparticle (AuNP)-modified glassy carbon (GC) electrode interface (GC-Ph-AuNP)-based biosensor for detecting carcinoembryonic antigen (CEA) was developed. Carbon 56-62 CEA cell adhesion molecule 3 Homo sapiens 157-160 22483934-0 2012 Electrochemical immunosensor for competitive detection of neuron specific enolase using functional carbon nanotubes and gold nanoprobe. Carbon 99-105 enolase 2 Homo sapiens 58-81 22483934-1 2012 An electrochemical immunosensor for detection of neuron specific enolase (NSE) was designed by immobilizing NSE covalently functionalized single-walled carbon nanotubes (NSE-SWNTs) on a glassy carbon electrode. Carbon 152-158 enolase 2 Homo sapiens 49-72 22483934-1 2012 An electrochemical immunosensor for detection of neuron specific enolase (NSE) was designed by immobilizing NSE covalently functionalized single-walled carbon nanotubes (NSE-SWNTs) on a glassy carbon electrode. Carbon 152-158 enolase 2 Homo sapiens 74-77 22483934-1 2012 An electrochemical immunosensor for detection of neuron specific enolase (NSE) was designed by immobilizing NSE covalently functionalized single-walled carbon nanotubes (NSE-SWNTs) on a glassy carbon electrode. Carbon 152-158 enolase 2 Homo sapiens 108-111 22483934-1 2012 An electrochemical immunosensor for detection of neuron specific enolase (NSE) was designed by immobilizing NSE covalently functionalized single-walled carbon nanotubes (NSE-SWNTs) on a glassy carbon electrode. Carbon 152-158 enolase 2 Homo sapiens 108-111 22483934-1 2012 An electrochemical immunosensor for detection of neuron specific enolase (NSE) was designed by immobilizing NSE covalently functionalized single-walled carbon nanotubes (NSE-SWNTs) on a glassy carbon electrode. Carbon 193-199 enolase 2 Homo sapiens 49-72 22483934-1 2012 An electrochemical immunosensor for detection of neuron specific enolase (NSE) was designed by immobilizing NSE covalently functionalized single-walled carbon nanotubes (NSE-SWNTs) on a glassy carbon electrode. Carbon 193-199 enolase 2 Homo sapiens 74-77 22524674-8 2012 The C-H bond can be readily activated by MH(+) (M = Os, Ir, and Pt) with a negligible barrier in the low-spin state; thus, OsH(+), IrH(+), and PtH(+) are likely to be excellent mediators for the activition of the C-H bond of methane. Carbon 4-5 parathyroid hormone Homo sapiens 143-146 22524674-8 2012 The C-H bond can be readily activated by MH(+) (M = Os, Ir, and Pt) with a negligible barrier in the low-spin state; thus, OsH(+), IrH(+), and PtH(+) are likely to be excellent mediators for the activition of the C-H bond of methane. Carbon 213-214 parathyroid hormone Homo sapiens 143-146 22231731-15 2012 Iloprost downregulated poly I:C-induced histone H3K4 trimethylation in the TNFA gene promoter region via suppressing translocation of histone 3 lysine 4 (H3K4)-specific methyltransferases MLL (mixed lineage leukemia) and WDR5 (WD repeat domain 5). Carbon 30-31 tumor necrosis factor Homo sapiens 75-79 22231731-15 2012 Iloprost downregulated poly I:C-induced histone H3K4 trimethylation in the TNFA gene promoter region via suppressing translocation of histone 3 lysine 4 (H3K4)-specific methyltransferases MLL (mixed lineage leukemia) and WDR5 (WD repeat domain 5). Carbon 30-31 WD repeat domain 5 Homo sapiens 221-225 22231731-15 2012 Iloprost downregulated poly I:C-induced histone H3K4 trimethylation in the TNFA gene promoter region via suppressing translocation of histone 3 lysine 4 (H3K4)-specific methyltransferases MLL (mixed lineage leukemia) and WDR5 (WD repeat domain 5). Carbon 30-31 WD repeat domain 5 Homo sapiens 227-245 22571318-0 2012 Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP kinase-dependent and -independent mechanisms in mouse RAW264.7 macrophages. Carbon 13-19 nitric oxide synthase 2, inducible Mus musculus 47-51 22336660-11 2012 CONCLUSION: The levels of pre-PCI CRP were strongly associated with ISR, whereas diabetes, serum levels of TC, LDL-C, and non-HDL-C were significantly correlated with coronary lesion progression. Carbon 0-1 C-reactive protein Homo sapiens 34-37 22428155-0 2012 Ultrasensitive electrochemiluminescence immunosensor using PtAg@carbon nanocrystals composites as labels and carbon nanotubes-chitosan/gold nanoparticles as enhancer. Carbon 64-70 rhomboid domain containing 3 Homo sapiens 59-63 22428155-1 2012 An ultrasensitive electrochemiluminescence (ECL) immunosensor was developed using PtAg@carbon nanocrystals (CNCs) as excellent labels based on carbon nanotubes-chitosan/AuNPs (CNT-CHIT/AuNPs) composite modified screen-printed carbon electrodes (SPCEs) for prostate protein antigen (PSA) detection. Carbon 87-93 rhomboid domain containing 3 Homo sapiens 82-86 22428155-1 2012 An ultrasensitive electrochemiluminescence (ECL) immunosensor was developed using PtAg@carbon nanocrystals (CNCs) as excellent labels based on carbon nanotubes-chitosan/AuNPs (CNT-CHIT/AuNPs) composite modified screen-printed carbon electrodes (SPCEs) for prostate protein antigen (PSA) detection. Carbon 143-149 rhomboid domain containing 3 Homo sapiens 82-86 22428155-1 2012 An ultrasensitive electrochemiluminescence (ECL) immunosensor was developed using PtAg@carbon nanocrystals (CNCs) as excellent labels based on carbon nanotubes-chitosan/AuNPs (CNT-CHIT/AuNPs) composite modified screen-printed carbon electrodes (SPCEs) for prostate protein antigen (PSA) detection. Carbon 143-149 rhomboid domain containing 3 Homo sapiens 82-86 22490007-0 2012 Polymorphic phases of sp3-hybridized carbon under cold compression. Carbon 37-43 Sp3 transcription factor Homo sapiens 22-25 22431524-3 2012 Here we show that when detached from the matrix, untransformed mammary epithelial cells undergo metabolic reprogramming by markedly upregulating pyruvate dehydrogenase (PDH) kinase 4 (PDK4) through estrogen-related receptor gamma (ERRgamma), thereby inhibiting PDH and attenuating the flux of glycolytic carbon into mitochondrial oxidation. Carbon 304-310 pyruvate dehydrogenase kinase 4 Homo sapiens 145-182 22056068-6 2012 Compared to integrin expression in unirradiated cells, carbon ion irradiation caused decreased integrin expression and inhibited cell migration on both Vn and Fn. Carbon 55-61 fibronectin 1 Homo sapiens 159-161 22056068-8 2012 In contrast to photon RT, carbon ion RT causes decreased integrin expression and suppresses glioma cell migration on both Vn and Fn, thus promising improved local control. Carbon 26-32 fibronectin 1 Homo sapiens 129-131 22431524-3 2012 Here we show that when detached from the matrix, untransformed mammary epithelial cells undergo metabolic reprogramming by markedly upregulating pyruvate dehydrogenase (PDH) kinase 4 (PDK4) through estrogen-related receptor gamma (ERRgamma), thereby inhibiting PDH and attenuating the flux of glycolytic carbon into mitochondrial oxidation. Carbon 304-310 pyruvate dehydrogenase kinase 4 Homo sapiens 184-188 22431524-3 2012 Here we show that when detached from the matrix, untransformed mammary epithelial cells undergo metabolic reprogramming by markedly upregulating pyruvate dehydrogenase (PDH) kinase 4 (PDK4) through estrogen-related receptor gamma (ERRgamma), thereby inhibiting PDH and attenuating the flux of glycolytic carbon into mitochondrial oxidation. Carbon 304-310 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 169-172 22402605-0 2012 Fermi energy level tuning for high performance dye sensitized solar cells using sp2 selective nitrogen-doped carbon nanotube channels. Carbon 109-115 Sp2 transcription factor Homo sapiens 80-83 22919827-4 2012 From 1997 to 2006, the total organic carbon storage in the urban built-up areas increased from 0.13-0.19 Pg C (averagely 0.16 Pg C) to 0.28-0.41 Pg C (averagely 0.34 Pg C), and the organic carbon density increased from 9.86-14.03 kg C x m(-2) (averagely 11.95 kg C x m(-2)) to 10.54-15.54 kg C x m(-2) (averagely 13.04 kg C x m(-2)). Carbon 37-43 progastricsin Homo sapiens 105-109 22919827-4 2012 From 1997 to 2006, the total organic carbon storage in the urban built-up areas increased from 0.13-0.19 Pg C (averagely 0.16 Pg C) to 0.28-0.41 Pg C (averagely 0.34 Pg C), and the organic carbon density increased from 9.86-14.03 kg C x m(-2) (averagely 11.95 kg C x m(-2)) to 10.54-15.54 kg C x m(-2) (averagely 13.04 kg C x m(-2)). Carbon 37-43 progastricsin Homo sapiens 126-130 22919827-4 2012 From 1997 to 2006, the total organic carbon storage in the urban built-up areas increased from 0.13-0.19 Pg C (averagely 0.16 Pg C) to 0.28-0.41 Pg C (averagely 0.34 Pg C), and the organic carbon density increased from 9.86-14.03 kg C x m(-2) (averagely 11.95 kg C x m(-2)) to 10.54-15.54 kg C x m(-2) (averagely 13.04 kg C x m(-2)). Carbon 37-43 progastricsin Homo sapiens 126-130 22919827-4 2012 From 1997 to 2006, the total organic carbon storage in the urban built-up areas increased from 0.13-0.19 Pg C (averagely 0.16 Pg C) to 0.28-0.41 Pg C (averagely 0.34 Pg C), and the organic carbon density increased from 9.86-14.03 kg C x m(-2) (averagely 11.95 kg C x m(-2)) to 10.54-15.54 kg C x m(-2) (averagely 13.04 kg C x m(-2)). Carbon 37-43 progastricsin Homo sapiens 126-130 22475216-2 2012 In one series, C-3 hydroxyl derivatives were studied leading to a very active compound, when the C-3 hydroxyl group assumes 3beta stereochemistry (1, IC(50) = 0.18 muM). Carbon 15-16 latexin Homo sapiens 164-167 22365749-4 2012 Here, we exploited this property using C-reactive protein (CRP) specific RNA aptamers as probes that were immobilized by physical adsorption on carbon nanotubes (CNTs) activated gold interdigitated electrodes of capacitors. Carbon 144-150 C-reactive protein Homo sapiens 39-57 22365749-4 2012 Here, we exploited this property using C-reactive protein (CRP) specific RNA aptamers as probes that were immobilized by physical adsorption on carbon nanotubes (CNTs) activated gold interdigitated electrodes of capacitors. Carbon 144-150 C-reactive protein Homo sapiens 59-62 20967558-2 2012 Fructosamine-3-kinase (FN3K), an enzyme found in mammals and birds, phosphorylates fructosamines on the third carbon of their sugar moiety, making them unstable and causing them to detach from proteins. Carbon 110-116 fructosamine 3 kinase Homo sapiens 0-21 22354722-0 2012 Probing the structure of lysozyme-carbon-nanotube hybrids with molecular dynamics. Carbon 34-40 lysozyme Homo sapiens 25-33 22354722-1 2012 Lysozyme has been successfully used to solvate carbon nanotubes (CNT). Carbon 47-53 lysozyme Homo sapiens 0-8 20967558-2 2012 Fructosamine-3-kinase (FN3K), an enzyme found in mammals and birds, phosphorylates fructosamines on the third carbon of their sugar moiety, making them unstable and causing them to detach from proteins. Carbon 110-116 fructosamine 3 kinase Homo sapiens 23-27 20967558-7 2012 As with FN3K, the third carbon is phosphorylated and this leads to destabilization of the ketoamines. Carbon 24-30 fructosamine 3 kinase Homo sapiens 8-12 22363024-0 2012 Biogenic carbon-enriched and pollutant depleted SRF from commercial and pretreated heterogeneous waste generated by NIR sensor-based sorting. Carbon 9-15 NOC2 like nucleolar associated transcriptional repressor Homo sapiens 116-119 22381049-0 2012 Design and synthesis of 4-alkynyl pyrazoles as inhibitors of PDE4: a practical access via Pd/C-Cu catalysis. Carbon 93-94 phosphodiesterase 4A Homo sapiens 61-65 21429045-1 2012 The mitochondrial tricarboxylate carrier supplies cytosol with the carbon units necessary for hepatic lipogenesis. Carbon 67-73 solute carrier family 25 member 1 Rattus norvegicus 4-40 22311646-8 2012 A glycolaldehyde treatment and the overexpression of ADH1 cause changes in the fermentation products so as to balance the metabolic carbon flux and the redox status. Carbon 132-138 alcohol dehydrogenase ADH1 Saccharomyces cerevisiae S288C 53-57 22311980-2 2012 Our previous discovery/deduction that a six-membered arogenate dehydratase (ADT1-6) gene family encodes the final step in Phe biosynthesis in Arabidopsis thaliana raised the fascinating question whether individual ADT isoenzymes (or combinations thereof) differentially modulated carbon flux to lignins, proteins, etc. Carbon 280-286 arogenate dehydratase 1 Arabidopsis thaliana 76-82 22360840-6 2012 The expression of marker genes for cell division (CycB) and cell wall extension (NtLRX1) was also up-regulated in cells exposed to MWCNTs compared to control cells or those exposed to activated carbon only. Carbon 194-200 leucine-rich repeat extensin-like protein 4 Nicotiana tabacum 81-87 21549726-7 2012 Furthermore, we observed an increase in peripheral poly I:C-induced IL-6, TNF-alpha, MCP-1, and MIP-1alpha, but not IL-1beta. Carbon 58-59 interleukin 6 Mus musculus 68-72 22316245-3 2012 In an in vitro system, we previously demonstrated that targeted drug delivery to cancer cells overexpressing epidermal growth factor receptor (EGFR+) can be achieved by poly(ethylene glycol)-functionalized carbon nanovectors simply mixed with a drug, paclitaxel, and an antibody that binds to the epidermal growth factor receptor, cetuximab. Carbon 206-212 epidermal growth factor receptor Homo sapiens 297-329 22180857-1 2012 A simple and highly sensitive electrochemiluminescent immunosensor based on nanocomposite architecture of the one-pot synthesized carbon nanodots and Nafion composite film was proposed for the detection of alpha-fetoprotein. Carbon 130-136 alpha fetoprotein Homo sapiens 206-223 22316245-3 2012 In an in vitro system, we previously demonstrated that targeted drug delivery to cancer cells overexpressing epidermal growth factor receptor (EGFR+) can be achieved by poly(ethylene glycol)-functionalized carbon nanovectors simply mixed with a drug, paclitaxel, and an antibody that binds to the epidermal growth factor receptor, cetuximab. Carbon 206-212 epidermal growth factor receptor Homo sapiens 109-141 22316245-3 2012 In an in vitro system, we previously demonstrated that targeted drug delivery to cancer cells overexpressing epidermal growth factor receptor (EGFR+) can be achieved by poly(ethylene glycol)-functionalized carbon nanovectors simply mixed with a drug, paclitaxel, and an antibody that binds to the epidermal growth factor receptor, cetuximab. Carbon 206-212 epidermal growth factor receptor Homo sapiens 143-148 22329538-4 2012 Sm@C(84)(II) can be identified as Sm@C(2)(11)-C(84) on the basis of the similarity of its UV/vis/NIR spectrum with that of Yb@C(2)(11)-C(84), whose carbon cage has been characterized by (13)C NMR spectroscopy. Carbon 148-154 NOC2 like nucleolar associated transcriptional repressor Homo sapiens 97-100 21549726-7 2012 Furthermore, we observed an increase in peripheral poly I:C-induced IL-6, TNF-alpha, MCP-1, and MIP-1alpha, but not IL-1beta. Carbon 58-59 tumor necrosis factor Mus musculus 74-83 21549726-7 2012 Furthermore, we observed an increase in peripheral poly I:C-induced IL-6, TNF-alpha, MCP-1, and MIP-1alpha, but not IL-1beta. Carbon 58-59 mast cell protease 1 Mus musculus 85-90 22119572-5 2012 Transmission electron-microscopy showed that dimeric transferrin, but not monomeric transferrin, deposited on carbon-coated formvar grids forms rounded (circular) structures ca. Carbon 110-116 transferrin Homo sapiens 53-64 22230694-0 2012 Amperometric acetylcholine biosensor based on self-assembly of gold nanoparticles and acetylcholinesterase on the sol-gel/multi-walled carbon nanotubes/choline oxidase composite-modified platinum electrode. Carbon 135-141 acetylcholinesterase (Cartwright blood group) Homo sapiens 86-106 22230694-1 2012 A novel acetylcholinesterase (AChE)/choline oxidase (ChOx) bienzyme amperometric acetylcholine biosensor based on gold nanoparticles (AuNPs) and multi-walled carbon nanotubes (MWCNTs) has been successfully developed by self-assembly process in combination of sol-gel technique. Carbon 158-164 acetylcholinesterase (Cartwright blood group) Homo sapiens 8-28 22230694-1 2012 A novel acetylcholinesterase (AChE)/choline oxidase (ChOx) bienzyme amperometric acetylcholine biosensor based on gold nanoparticles (AuNPs) and multi-walled carbon nanotubes (MWCNTs) has been successfully developed by self-assembly process in combination of sol-gel technique. Carbon 158-164 acetylcholinesterase (Cartwright blood group) Homo sapiens 30-34 22266675-4 2012 Trioctylamine molecules undergo C-N bond cleavage to form octylamine via the redox reaction between the Co(III) and trioctylamine. Carbon 32-33 mitochondrially encoded cytochrome c oxidase III Homo sapiens 104-111 22376179-0 2012 Copper ion mediated selective cleavage of C-S bond in ferrocenylthiosemicarbazone forming mixed geometrical [(PPh3)Cu(mu-S)2Cu(PPh3)2] having Cu2S2 core: toward a new avenue in copper-sulfur chemistry. Carbon 0-1 caveolin 1 Homo sapiens 110-114 22376179-0 2012 Copper ion mediated selective cleavage of C-S bond in ferrocenylthiosemicarbazone forming mixed geometrical [(PPh3)Cu(mu-S)2Cu(PPh3)2] having Cu2S2 core: toward a new avenue in copper-sulfur chemistry. Carbon 0-1 caveolin 1 Homo sapiens 127-131 22055155-4 2012 The PCB uptakes in passive samplers decreased up to 73% with a 3.7 dry wt.% AC dose after five years, confirming the temporal enhancement of the amendment benefit from a 19% reduction with a 4.4% dose observed within one month. Carbon 76-78 pyruvate carboxylase Homo sapiens 4-7 22276528-6 2012 This reagentless biosensing approach was capable of detecting H(2)O(2), a simple molecule but plays an important role in analytical and biological chemistry, as low as 0.1 muM with linearity of 0.1-60 muM and a response time of <0.8 s, comparing favorably with other carbon based electrodes (5 s). Carbon 270-276 latexin Homo sapiens 172-175 22080429-3 2012 The gl1 mutant showed a similar wax composition as the Col-0 wild type with slightly reduced amounts of C(29), C(31) and C(33) alkanes by GC/MS and GC/FID analyses. Carbon 55-56 myb domain protein 0 Arabidopsis thaliana 4-7 22080429-3 2012 The gl1 mutant showed a similar wax composition as the Col-0 wild type with slightly reduced amounts of C(29), C(31) and C(33) alkanes by GC/MS and GC/FID analyses. Carbon 104-105 myb domain protein 0 Arabidopsis thaliana 4-7 22080429-3 2012 The gl1 mutant showed a similar wax composition as the Col-0 wild type with slightly reduced amounts of C(29), C(31) and C(33) alkanes by GC/MS and GC/FID analyses. Carbon 104-105 myb domain protein 0 Arabidopsis thaliana 4-7 25049568-11 2012 The concentration of t-10, c-12 18:2, c-9 t-11 18:2, 18:3, eicosapentaenoic acid (EPA, 20:5) and docosahexaenoic acid (DHA, 22:6) increased (p<0.05) in FO and FOCO diets in comparison with the other two diets. Carbon 4-5 complement C9 Bos taurus 38-41 22237295-6 2012 RESULTS: We found effects of particle number, black carbon, nitrogen dioxide (NO(2)), and carbon monoxide (CO) on fibrinogen. Carbon 52-58 fibrinogen beta chain Homo sapiens 114-124 22237295-8 2012 Particle number, black carbon, NO(2), CO, PM(2.5), and sulfates were associated with ICAM-1 and VCAM-1. Carbon 23-29 vascular cell adhesion molecule 1 Homo sapiens 96-102 21562677-6 2012 Finally a rosuvastatin (Crestor ) intermediate is produced using a deoxy ribose aldolase (DERA) enzyme in which two carbon-carbon bonds and two chiral centres are formed in the same process step. Carbon 116-122 deoxyribose-phosphate aldolase Homo sapiens 90-94 22040060-10 2012 TNF-alpha production of macrophages with the nitric oxide (NO) inhibitor-treatment increased after carbon-ion broad-beam. Carbon 99-105 tumor necrosis factor Homo sapiens 0-9 22259189-0 2012 Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARalpha, interferon-gamma, and interleukin-10. Carbon 14-20 peroxisome proliferator activated receptor alpha Mus musculus 164-173 22259189-0 2012 Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARalpha, interferon-gamma, and interleukin-10. Carbon 14-20 interferon gamma Mus musculus 175-191 22259189-0 2012 Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARalpha, interferon-gamma, and interleukin-10. Carbon 14-20 interleukin 10 Mus musculus 197-211 22027091-6 2012 Mutational analysis of the Arabidopsis GL1 locus showed that while the frequency of generation of glabrous mutant sectors was not different between the two types of carbon-ion irradiation, large deletions (>~30kb) were six times more frequently induced by carbon ions near the range end. Carbon 259-265 myb domain protein 0 Arabidopsis thaliana 39-42 22218737-1 2012 Unique monkshoodvine root-bark like morphology carbon materials (MLC) have been successfully synthesized under hydrothermal conditions. Carbon 47-53 modulator of VRAC current 1 Homo sapiens 65-68 22271351-7 2012 CU can combine with the BSA-CTS complex through its center carbonyl carbon, and CTS plays a key role in promoting the energy transfer process by shortening the distance between BSA and CU. Carbon 59-65 albumin Homo sapiens 24-27 22271351-7 2012 CU can combine with the BSA-CTS complex through its center carbonyl carbon, and CTS plays a key role in promoting the energy transfer process by shortening the distance between BSA and CU. Carbon 59-65 albumin Homo sapiens 177-180 22330799-6 2012 Using the HXT1 promoter to control ERG9 expression, it was possible to divert the carbon flux from sterol synthesis towards alpha-santalene improving the productivity by 3.4 fold. Carbon 82-88 bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase Saccharomyces cerevisiae S288C 35-39 21562677-6 2012 Finally a rosuvastatin (Crestor ) intermediate is produced using a deoxy ribose aldolase (DERA) enzyme in which two carbon-carbon bonds and two chiral centres are formed in the same process step. Carbon 123-129 deoxyribose-phosphate aldolase Homo sapiens 90-94 21924301-8 2012 In most cases, substitution of carbon with nitrogen and oxygen was related to increased compound degradation in comparison to unalkylated and sulphur- or unsubstituted PAH with a similar ring number.The obtained results indicate that GC2/MS can be employed for the rapid assessment of a large variety of structurally heterogeneous environmental contaminants. Carbon 31-37 solute carrier family 25 member 18 Homo sapiens 234-237 22158639-1 2012 In this work, we reported a simple and sensitive sandwich-type electrochemiluminescence (ECL) immunosensor for carcinoembryonic antigen (CEA) on a gold nanoparticles (AuNPs) modified glassy carbon electrode (GCE). Carbon 190-196 CEA cell adhesion molecule 3 Homo sapiens 111-135 22200651-0 2012 Label-free impedimetric aptasensor for lysozyme detection based on carbon nanotube-modified screen-printed electrodes. Carbon 67-73 lysozyme Homo sapiens 39-47 22200651-3 2012 An amino-modified version of the DNA aptamer-recognizing lysozyme was covalently immobilized on the surface of multiwalled carbon nanotube-modified screen-printed electrodes (MWCNT-SPEs), which were employed for measurements and have improved properties compared with bare SPEs. Carbon 123-129 lysozyme Homo sapiens 57-65 22200651-4 2012 This carbon nanotube setup enabled the reliable monitoring of the interaction of lysozyme with its cognate aptamer by EIS transduction of the resistance to charge transfer (R(ct)) in the presence of 2.5 mM [Fe(CN)6]3-/4-. Carbon 5-11 lysozyme Homo sapiens 81-89 22276612-0 2012 Intermolecular Ritter-type C-H amination of unactivated sp3 carbons. Carbon 60-67 Sp3 transcription factor Homo sapiens 56-59 22158639-1 2012 In this work, we reported a simple and sensitive sandwich-type electrochemiluminescence (ECL) immunosensor for carcinoembryonic antigen (CEA) on a gold nanoparticles (AuNPs) modified glassy carbon electrode (GCE). Carbon 190-196 CEA cell adhesion molecule 3 Homo sapiens 137-140 22346895-1 2012 The asymmetric unit of the title complex, [Pb(C(8)H(5)O(4))(C(9)H(6)NO)](n), comprises a Pb(II) cation, a quinolin-8-olate anion and a 3-carb-oxy-benzoate anion. Carbon 46-47 submaxillary gland androgen regulated protein 3B Homo sapiens 89-95 22063315-4 2012 The prepared anti-AFP/GNPs/TMCS-MPS particles were used to modify glassy carbon electrode (GCE) to construct a label-free immunosensor. Carbon 73-79 alpha fetoprotein Homo sapiens 18-21 22101058-6 2012 Both, chiA abundance and chitinase activity correlated well with organic carbon, nitrogen, and concentrations of particulate GlcN. Carbon 73-79 chitinase acidic Homo sapiens 6-10 22101058-6 2012 Both, chiA abundance and chitinase activity correlated well with organic carbon, nitrogen, and concentrations of particulate GlcN. Carbon 73-79 chitinase acidic Homo sapiens 25-34 21113716-6 2012 The genotype frequency of G915C TGF-beta1 polymorphism in RA and CS was G/G (91.7%), G/C (8.3%), C/C (0%) and G/G (85.8%), G/C (14.2%), C/C (0%), respectively, without significant differences. Carbon 30-31 transforming growth factor beta 1 Homo sapiens 32-41 22094012-3 2012 Cultivation with glucose or ethanol as carbon substrate revealed that Adh1 was the only alcohol dehydrogenase capable of efficiently catalysing the reduction of acetaldehyde to ethanol. Carbon 39-45 alcohol dehydrogenase ADH1 Saccharomyces cerevisiae S288C 70-74 25101809-11 2012 Low maternal vitamin B12 status in pregnancy and prolonged breast-feeding results in disturbed one-carbon metabolism in offspring at 2y. Carbon 99-105 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 21-24 22037182-1 2012 The chemical shift of the carboxylate carbon of Z-tryptophan is increased from 179.85 to 182.82 ppm and 182.87 ppm on binding to thermolysin and stromelysin-1 respectively. Carbon 38-44 matrix metallopeptidase 3 Homo sapiens 145-158 21880553-2 2012 An acetylcholinesterase (AChE) based amperometric biosensor was developed by silica sol-gel film immobilization of the enzyme onto the carbon paste electrode. Carbon 135-141 acetylcholinesterase (Cartwright blood group) Homo sapiens 25-29 22155313-0 2012 Carbon nanotubes provoke inflammation by inducing the pro-inflammatory genes IL-1beta and IL-6. Carbon 0-6 interleukin 1 beta Mus musculus 77-85 22155313-0 2012 Carbon nanotubes provoke inflammation by inducing the pro-inflammatory genes IL-1beta and IL-6. Carbon 0-6 interleukin 6 Mus musculus 90-94 21987236-0 2012 Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) expression is epigenetically regulated by one-carbon metabolism in invasive duct cell carcinoma of breast. Carbon 104-110 BCL2 interacting protein 3 Homo sapiens 0-49 21987236-0 2012 Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) expression is epigenetically regulated by one-carbon metabolism in invasive duct cell carcinoma of breast. Carbon 104-110 BCL2 interacting protein 3 Homo sapiens 51-56 21987236-1 2012 In view of recent studies highlighting the prognostic relevance of expression and CpG island methylator phenotype (CIMP) of Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) in invasive duct cell carcinoma (IDC), we hypothesized in this article that impaired one-carbon metabolism might influence CIMP phenotype of BNIP3. Carbon 271-277 BCL2 interacting protein 3 Homo sapiens 124-173 21987236-1 2012 In view of recent studies highlighting the prognostic relevance of expression and CpG island methylator phenotype (CIMP) of Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) in invasive duct cell carcinoma (IDC), we hypothesized in this article that impaired one-carbon metabolism might influence CIMP phenotype of BNIP3. Carbon 271-277 BCL2 interacting protein 3 Homo sapiens 175-180 22319437-6 2012 The dFBA profiled biologically meaningful dynamic MR-1 metabolisms: 1. the oxidative TCA cycle fluxes increased initially and then decreased in the late growth stage; 2. fluxes in the pentose phosphate pathway and gluconeogenesis were stable in the exponential growth period; and 3. the glyoxylate shunt was up-regulated when acetate became the main carbon source for MR-1 growth. Carbon 350-356 Aldolase 1 Drosophila melanogaster 4-8 21113716-6 2012 The genotype frequency of G915C TGF-beta1 polymorphism in RA and CS was G/G (91.7%), G/C (8.3%), C/C (0%) and G/G (85.8%), G/C (14.2%), C/C (0%), respectively, without significant differences. Carbon 65-66 transforming growth factor beta 1 Homo sapiens 32-41 21113716-6 2012 The genotype frequency of G915C TGF-beta1 polymorphism in RA and CS was G/G (91.7%), G/C (8.3%), C/C (0%) and G/G (85.8%), G/C (14.2%), C/C (0%), respectively, without significant differences. Carbon 65-66 transforming growth factor beta 1 Homo sapiens 32-41 21113716-6 2012 The genotype frequency of G915C TGF-beta1 polymorphism in RA and CS was G/G (91.7%), G/C (8.3%), C/C (0%) and G/G (85.8%), G/C (14.2%), C/C (0%), respectively, without significant differences. Carbon 65-66 transforming growth factor beta 1 Homo sapiens 32-41 22123120-4 2012 The sensitivity enhancement with nearly two orders of magnitude was gained, compared with the bare carbon paste electrode, with the detection limit of 0.91 muM (S/N=3) for hydrazine. Carbon 99-105 latexin Homo sapiens 156-159 22213085-0 2012 Nanographite impurities in carbon nanotubes: their influence on the oxidation of insulin, nitric oxide, and extracellular thiols. Carbon 27-33 insulin Homo sapiens 81-88 22209981-2 2012 In the present study, we demonstrated the polyI:C-induced gene expression of the damage associated molecular pattern (DAMP) molecules S100A8 and S100A9, while other S100 genes were not affected. Carbon 48-49 S100 calcium binding protein A1 Homo sapiens 134-138 22260391-5 2012 The results indicated that the substrate temperature, grain size, surface roughness, and sp3 carbon content in the films decreased with decreasing pressure. Carbon 93-99 Sp3 transcription factor Homo sapiens 89-92 22260391-6 2012 The reason is due to the great reduction of Halpha emission to lower the etching of sp2 carbon phase, resulting from the increase of mean free path with decreasing pressure. Carbon 88-94 Sp2 transcription factor Homo sapiens 84-87 22260391-8 2012 The 250-nm-thick UNCD film was synthesized on glass substrates (glass transition temperature [Tg] 557 C) using the unique LPLT (30 Torr/460 C) microwave plasma jet, which produced UNCD films with a high sp3 carbon content (95.65%) and offered high optical transmittance (approximately 86% at 700 nm). Carbon 207-213 Sp3 transcription factor Homo sapiens 203-206 22154168-1 2012 The electrochemical biosensors based on poly(o-phenylenediamine) (PoPD) and acetylcholinesterase (AChE) and choline oxidase (ChO) enzymes were fabricated on carbon fibre (CF) substrate. Carbon 157-163 acetylcholinesterase (Cartwright blood group) Homo sapiens 76-96 22154168-1 2012 The electrochemical biosensors based on poly(o-phenylenediamine) (PoPD) and acetylcholinesterase (AChE) and choline oxidase (ChO) enzymes were fabricated on carbon fibre (CF) substrate. Carbon 157-163 acetylcholinesterase (Cartwright blood group) Homo sapiens 98-102 22267809-1 2012 Tethering a single lysozyme molecule to a carbon nanotube field-effect transistor produced a stable, high-bandwidth transducer for protein motion. Carbon 42-48 lysozyme Homo sapiens 19-27 22230188-6 2012 Indeed, the TRX2 overexpressing strain presented increased activity of the central carbon metabolism enzymes. Carbon 83-89 thioredoxin TRX2 Saccharomyces cerevisiae S288C 12-16 22265488-2 2012 The electrode comprises a Co(II)-exchanged zeolite Y as modifier in carbon paste matrix. Carbon 68-74 mitochondrially encoded cytochrome c oxidase II Homo sapiens 26-31 22265488-3 2012 First, the electrochemical behavior of Co(II) in modified carbon paste electrode was studied. Carbon 58-64 mitochondrially encoded cytochrome c oxidase II Homo sapiens 39-45 22265524-2 2012 Characterization studies revealed the presence of edge plane sites and surface carbon-oxygen functionalities at the surface of the CNP material. Carbon 79-85 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 131-134 22129100-1 2012 C(7)H(12)(2+) (1), the prototype hexacoordinate carbonium dication was found to be a viable minimum at the MP2/6-31G** and MP2/cc-pVTZ levels. Carbon 48-57 major intrinsic protein of lens fiber Homo sapiens 107-112 22051630-6 2012 Our results demonstrate that different chloride ion concentrations can influence the speciation in the acidic pH range but at biologically relevant conditions (pH = 7.4, c(Cl(-)) = 0.16 M) and at c(M) = 1 muM [{Ru(eta(6)-p-cym)}(2)(mu(2)-OH)(3)](+) is predominant in the absence of any coordinating ligands. Carbon 39-40 latexin Homo sapiens 205-208 22269867-4 2012 The formation of a chroman ring by intramolecular cyclization between a sp2 carbon from the prenyl group with the hydroxyl substituent in the ortho position occurred with some phenols. Carbon 76-82 Sp2 transcription factor Homo sapiens 72-75 22232218-0 2012 An sp2 and sp3 hybrid nanocrystalline carbon film electrode for anodic stripping voltammetry and its application for electrochemical immunoassay. Carbon 38-44 Sp2 transcription factor Homo sapiens 3-6 22221278-1 2012 The carbon-supported cobalt(III) complex of beta-pyrrole-brominated 5,10,15-tris(pentafluorophenyl)corrole [Co(tpfc)Br(8)/C] is introduced as a nonplatinum alternative for electrocatalytic oxygen reduction in aqueous solutions. Carbon 4-10 mitochondrially encoded cytochrome c oxidase III Homo sapiens 28-31 22232218-0 2012 An sp2 and sp3 hybrid nanocrystalline carbon film electrode for anodic stripping voltammetry and its application for electrochemical immunoassay. Carbon 38-44 Sp3 transcription factor Homo sapiens 11-14 23046715-8 2012 Applying the method to E. coli central carbon metabolic system, we found that multiple enzymes including phosphoglycerate kinase, enolase, transketolase-b, etc., had critical roles in the system in terms of both system states and dynamical stability. Carbon 39-45 Enolase Escherichia coli 130-137 22915854-0 2012 Conformational changes of fibrinogen in dispersed carbon nanotubes. Carbon 50-56 fibrinogen beta chain Homo sapiens 26-36 22792101-10 2012 The ROC curve demonstrated that TC/HDL-C ratio had higher sensitivity and specificity in diagnosing PCOS with insulin resistance. Carbon 6-7 insulin Homo sapiens 110-117 22942686-4 2012 Functional genomic analysis using GS2-minus mutant reveals the key role of GS2 in the metabolic control of the plants and, more particularly, in carbon metabolism. Carbon 145-151 patatin like phospholipase domain containing 4 Homo sapiens 34-37 22934778-2 2012 Alkyl esters bearing chain lengths of 4 (P4), 7 (P7) and 10 (P10) carbons were synthesized and their oxidation potential, hydrophobicity, antiradical activity, inhibition of superoxide anion (O2 (-)), and the abilities to affect hypochlorous acid (HOCl) production by leukocytes and inhibit myeloperoxidase (MPO) chlorinating activity were studied. Carbon 66-73 S100 calcium binding protein A10 Homo sapiens 61-64 22915854-2 2012 In this study, we identified that the functional intensity of carboxyl groups on carbon nanotubes, which correspond to the water dispersity or hydrophilicity of carbon nanotubes, can induce conformational changes in the fibrinogen domains. Carbon 81-87 fibrinogen beta chain Homo sapiens 220-230 22915854-2 2012 In this study, we identified that the functional intensity of carboxyl groups on carbon nanotubes, which correspond to the water dispersity or hydrophilicity of carbon nanotubes, can induce conformational changes in the fibrinogen domains. Carbon 161-167 fibrinogen beta chain Homo sapiens 220-230 22915854-3 2012 Also, elevation of carbon nanotube density can alter the secondary structures (ie, helices and beta sheets) of fibrinogen. Carbon 19-25 fibrinogen beta chain Homo sapiens 111-121 22915854-4 2012 Furthermore, fibrinogen that had been in contact with the nanoparticle material demonstrated a different pattern of heat denaturation compared with free fibrinogen as a result of a variation in hydrophilicity and concentration of carbon nanotubes. Carbon 230-236 fibrinogen beta chain Homo sapiens 13-23 22915854-5 2012 Considering the importance of interactions between carbon nanotubes and plasma proteins in the drug delivery system, this study elucidated the correlation between nanoscale physiochemical material properties of carbon nanotubes and associated structural changes in fibrinogen. Carbon 211-217 fibrinogen beta chain Homo sapiens 265-275 22362146-0 2012 Adsorption capacity of Cu(II) and Pb(II) onto carbon fiber produced from wool. Carbon 46-52 submaxillary gland androgen regulated protein 3B Homo sapiens 23-40 22846916-4 2012 Characterization of derivative strains lacking 3-dehydroquinate synthase activity showed that inactivation of pykA leads to an 8-fold increase in carbon flow to the common aromatic pathway. Carbon 146-152 pyruvate kinase Bacillus subtilis subsp. subtilis str. 168 110-114 22846916-5 2012 Quantitative real-time PCR analyses of 76 genes from several functional classes revealed a carbon starvation transcriptional pattern that includes a partial gluconeogenic response and overexpression of genes encoding non-PTS glucose importers in the strains lacking functional pykA, ptsG or ptsGHI genes. Carbon 91-97 pyruvate kinase Bacillus subtilis subsp. subtilis str. 168 277-281 21883555-11 2012 We propose that gl2 mutant seeds produce more oil due to increased carbon allocation to the embryo in the absence of seed coat mucilage biosynthesis. Carbon 67-73 HD-ZIP IV family of homeobox-leucine zipper protein with lipid-binding START domain-containing protein Arabidopsis thaliana 16-19 21812816-9 2012 Thus, we propose that the anti-apoptotic action with the alterations in apoptosis regulator provided by melatonin may be responsible at least in part for its antioxidant effect by the abolishing of carbon ion-induced oxidative stress along with increasing Nrf2 expression and antioxidant enzyme activity. Carbon 198-204 nuclear factor, erythroid derived 2, like 2 Mus musculus 256-260 22778656-3 2012 A model used to effectively describe the cytochrome P450 deposition onto carbon nanotubes was confirmed by Monte Carlo simulations. Carbon 73-79 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 41-56 23139834-3 2012 However this enzyme has also been frequently proposed to perform a critical function in inorganic carbon acquisition and CO(2) fixation and all mutants lacking Cah3 exhibit very poor growth after transfer to low CO(2) conditions. Carbon 98-104 uncharacterized protein Chlamydomonas reinhardtii 160-164 23056614-3 2012 Although the fate of three-carbon metabolites is largely determined by flux rate through the relevant enzymes, insulin plays a permissive role in this process. Carbon 27-33 insulin Homo sapiens 111-118 22829768-4 2012 betah/c-mediated activation of p38 MAPK drives expression of the anti-inflammatory and immunosuppressive cytokine IL-10, and inhibits both IL-12 and NOS2 expression in GBS-infected macrophages, which are critical factors in host defense. Carbon 6-7 interleukin 10 Mus musculus 114-119 22829768-7 2012 These data suggest p38 MAPK activation by betah/c contributes to evasion of host defense through induction of IL-10 expression and inhibition of macrophage activation, a new mechanism of action for a PFT and a novel anti-inflammatory role for p38 in the pathogenesis of invasive bacterial infection. Carbon 29-30 interleukin 10 Mus musculus 110-115 23112609-0 2012 Mechanisms for the direct electron transfer of cytochrome c induced by multi-walled carbon nanotubes. Carbon 84-90 cytochrome c, somatic Homo sapiens 47-59 23112609-1 2012 Multi-walled carbon nanotube (MWCNT)-modified electrodes can promote the direct electron transfer (DET) of cytochrome c (Cyt c). Carbon 13-19 cytochrome c, somatic Homo sapiens 107-119 23112609-1 2012 Multi-walled carbon nanotube (MWCNT)-modified electrodes can promote the direct electron transfer (DET) of cytochrome c (Cyt c). Carbon 13-19 cytochrome c, somatic Homo sapiens 121-126 22778656-0 2012 Electrochemical detection of anti-breast-cancer agents in human serum by cytochrome P450-coated carbon nanotubes. Carbon 96-102 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 73-88 22778656-2 2012 Multi-walled carbon nanotubes were functionalized with three different cytochrome P450 isoforms (CYP1A2, CYP2B6, and CYP3A4). Carbon 13-19 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 71-86 22778656-2 2012 Multi-walled carbon nanotubes were functionalized with three different cytochrome P450 isoforms (CYP1A2, CYP2B6, and CYP3A4). Carbon 13-19 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 117-123 22102762-0 2011 Methodological Advances Permit the Stereocontrolled Construction of Diverse Fully Synthetic Tetracyclines Containing an All-Carbon Quaternary Center at Position C5a. Carbon 124-130 complement C5a receptor 1 Homo sapiens 161-164 22766874-4 2012 A GDE made of carbon nanoparticles bound with 30% polytetrafluoroethylene (PTFE) (wt./wt.C) to a carbon fiber paper performed best and catalyzed H(2)O(2) production from oxygen in air with a coulombic efficiency of 95.1%. Carbon 14-20 amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase Homo sapiens 2-5 22766874-4 2012 A GDE made of carbon nanoparticles bound with 30% polytetrafluoroethylene (PTFE) (wt./wt.C) to a carbon fiber paper performed best and catalyzed H(2)O(2) production from oxygen in air with a coulombic efficiency of 95.1%. Carbon 97-103 amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase Homo sapiens 2-5 22160690-6 2011 This competition creates a translational bottleneck that balances the production of Gal1p and Cln3p and represents a posttranscriptional control mechanism that enhances the cell"s ability to adapt to changes in carbon source. Carbon 211-217 cyclin CLN3 Saccharomyces cerevisiae S288C 94-99 22102762-1 2011 Here we describe chemical innovations that enable the preparation of fully synthetic tetracyclines containing an all-carbon quaternary, stereogenic center at position C5a, a structurally novel class of compounds in this important family of therapeutic agents. Carbon 117-123 complement C5a receptor 1 Homo sapiens 167-170 22102762-2 2011 In the key transformation and an important extension of the powerful Michael-Claisen cyclization (AB plus D) approach to the construction of fully synthetic tetracyclines, we show that the six-membered C ring comprising a C5a quaternary carbon center can be assembled by highly stereocontrolled coupling reactions of beta-substituted AB enones and o-toluate ester anion D-ring precursors. Carbon 237-243 complement C5a receptor 1 Homo sapiens 222-225 22102762-4 2011 A C5a-C11a-bridged cyclopropane tetracycline precursor was found to undergo efficient and regioselective ring-opening reactions with a range of nucleophiles in the presence of magnesium bromide, thus providing another avenue for the preparation of fully synthetic tetracyclines containing an all-carbon quaternary center at position C5a. Carbon 296-302 complement C5a receptor 1 Homo sapiens 2-5 22102762-4 2011 A C5a-C11a-bridged cyclopropane tetracycline precursor was found to undergo efficient and regioselective ring-opening reactions with a range of nucleophiles in the presence of magnesium bromide, thus providing another avenue for the preparation of fully synthetic tetracyclines containing an all-carbon quaternary center at position C5a. Carbon 296-302 complement C5a receptor 1 Homo sapiens 333-336 22026549-1 2011 TYW1 catalyzes the condensation of N-methylguanosine with two carbon atoms from an unknown second substrate to form 4-demethylwyosine, which is a common intermediate in the biosynthesis of all of the hypermodified RNA bases related to wybutosine found in eukaryal and archaeal tRNA(Phe). Carbon 62-68 tRNA-yW synthesizing protein 1 homolog Homo sapiens 0-4 22077959-0 2011 Field-scale reduction of PCB bioavailability with activated carbon amendment to river sediments. Carbon 60-66 pyruvate carboxylase Homo sapiens 25-28 22077959-5 2011 By comparing measured reductions in bioaccumulation of tetra- and penta-chlorinated PCB congeners resulting from field application of activated carbon to a laboratory study where PCBs were preloaded onto activated carbon, it is evident that equilibrium sorption had not been achieved in the field. Carbon 144-150 pyruvate carboxylase Homo sapiens 84-87 22077959-5 2011 By comparing measured reductions in bioaccumulation of tetra- and penta-chlorinated PCB congeners resulting from field application of activated carbon to a laboratory study where PCBs were preloaded onto activated carbon, it is evident that equilibrium sorption had not been achieved in the field. Carbon 214-220 pyruvate carboxylase Homo sapiens 84-87 22077959-6 2011 Although other remedies may be appropriate for some highly contaminated sites, we show through this pilot study that PCB exposure from moderately contaminated river sediments may be managed effectively through activated carbon amendment in sediments. Carbon 220-226 pyruvate carboxylase Homo sapiens 117-120 22099656-0 2011 Application of chitosan/Fe3O4 microsphere-graphene composite modified carbon ionic liquid electrode for the electrochemical detection of the PCR product of soybean Lectin gene sequence. Carbon 70-76 LOW QUALITY PROTEIN: lectin Glycine max 164-170 21993142-1 2011 Microperoxidase-11 (MP-11) which has been immobilised in a matrix of chitosan-embedded gold nanoparticles on the surface of a glassy carbon electrode catalyzes the conversion of aromatic substances. Carbon 133-139 non-compact myelin associated protein Homo sapiens 0-25 21600321-3 2011 When AChE is immobilized into a paste carbon working electrode kept at +410 mV vs. Ag/AgCl electrode, the enzyme reaction rate using acetylthiocholine chloride (ATCl) as substrate is monitored as a current intensity. Carbon 38-44 acetylcholinesterase (Cartwright blood group) Homo sapiens 5-9 22151908-5 2011 The re-distribution of the carbon flux from biomass formation towards increased glycerol production under low phosphate led to increased transcript levels of the insulin gene, which was under the regulation of the TPI1 promoter. Carbon 27-33 insulin Homo sapiens 162-169 22168696-4 2011 Interpretation of the spectroscopic constants reveals that the carbon atom of CO is adjacent to I and participates in the weak bond in OC ICF(3). Carbon 63-69 cell division cycle associated 7 Homo sapiens 140-146 22151908-5 2011 The re-distribution of the carbon flux from biomass formation towards increased glycerol production under low phosphate led to increased transcript levels of the insulin gene, which was under the regulation of the TPI1 promoter. Carbon 27-33 triose-phosphate isomerase TPI1 Saccharomyces cerevisiae S288C 214-218 21664247-3 2011 PTH enhances vitamin D hydroxylation on carbon 1 in kidney cells thereby allowing the systemic release of 1-25-dihydroxy-vitamin D, which represents the fully active hormone. Carbon 40-46 parathyroid hormone Homo sapiens 0-3 21769670-1 2011 Methylenetetrahydrofolate reductase (MTHFR), a key enzyme in folate metabolism, synthesizes 5-methyltetrahydrofolate, the main circulatory form of folate which is required for maintaining nontoxic levels of homocysteine and providing one-carbon units for methylation. Carbon 238-244 methylenetetrahydrofolate reductase Mus musculus 0-35 21831043-5 2011 PDR18 activation under 2,4-D stress is regulated by the transcription factors Nrg1, controlling carbon source availability and the stress response, and, less significantly, Yap1, involved in oxidative stress and MDR, and Pdr3, a key regulator of the yeast PDR network, consistent with a broad role in stress defence. Carbon 96-102 ATP-binding cassette multidrug transporter PDR18 Saccharomyces cerevisiae S288C 0-5 21926297-5 2011 Specifically, a serine/threonine PAS-kinase, Rim15p, that is known to integrate phosphate, nitrogen, and carbon sensing, can also control Mn antioxidant activity in yeast. Carbon 105-111 protein kinase RIM15 Saccharomyces cerevisiae S288C 45-51 21964048-5 2011 The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3. Carbon 19-20 interleukin 1 beta Homo sapiens 90-98 21964048-5 2011 The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3. Carbon 19-20 interleukin 6 Homo sapiens 100-104 21964048-5 2011 The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3. Carbon 19-20 C-X-C motif chemokine ligand 8 Homo sapiens 106-110 21964048-5 2011 The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3. Carbon 19-20 tumor necrosis factor Homo sapiens 112-121 21964048-5 2011 The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3. Carbon 19-20 interferon alpha 1 Homo sapiens 123-132 21769670-1 2011 Methylenetetrahydrofolate reductase (MTHFR), a key enzyme in folate metabolism, synthesizes 5-methyltetrahydrofolate, the main circulatory form of folate which is required for maintaining nontoxic levels of homocysteine and providing one-carbon units for methylation. Carbon 238-244 methylenetetrahydrofolate reductase Mus musculus 37-42 21725842-3 2011 The aim of this study was to assess the effects, after intraperitoneal (ip) injection, of functionalized multi-walled carbon nanotubes (MWCNT) (carboxyl groups) on various hepatotoxicity and oxidative stress biomarkers (ROS, LHP, ALT, AST, ALP, and morphology of liver) in the mouse model. Carbon 118-124 transmembrane protease, serine 11d Mus musculus 235-238 22304097-3 2011 Considering recent evidence demonstrating that the contact angle of water on a graphitic plane is much higher than what was previously reported, we estimate the oxygen-carbon interaction for the recent SPC/Fw water model. Carbon 168-174 proline rich protein gene cluster Homo sapiens 202-205 21859392-6 2011 It was identified as an N-oxide derivative and, under hypoxia, it underwent retroreduction back to C-1305, what was extremely effective with participation of CYP3A4. Carbon 99-100 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 158-164 22433878-6 2011 Our results suggest that recombinant SAG1/2 were best expressed at 30oC, pH 6 and 1% methanol as the carbon source by X33 Pichia cells. Carbon 103-109 Sag1p Saccharomyces cerevisiae S288C 37-43 21946106-6 2011 In addition, C-721 inhibited TNF-alpha and IL-6 production at 10-50 muM. Carbon 13-14 tumor necrosis factor Mus musculus 29-38 21946106-6 2011 In addition, C-721 inhibited TNF-alpha and IL-6 production at 10-50 muM. Carbon 13-14 interleukin 6 Mus musculus 43-47 21900003-0 2011 Multiwalled carbon nanotubes dispersed in carminic acid for the development of catalase based biosensor for selective amperometric determination of H(2)O(2) and iodate. Carbon 12-18 catalase Homo sapiens 79-87 22132429-14 2004 (6) designed a peptide (VDKLLLHLKKLFREGQFNRNFESIIICRDRT-OH, denoted as the IL-13 peptide) based on these residues, then attached a TAMRA fluorescent label and conjugated the IL-13 peptide to a functionalized (carboxylated/hydroxylated) Gd-metallofullerene carbon cage (TAMRA-IL-13-f-Gd3N@C80). Carbon 256-262 interleukin 13 Homo sapiens 75-80 21999508-2 2011 Aminopiperidines that have a bicyclic aromatic moiety linked through a carbon to an ethyl bridge, such as 1, generally show potent broad-spectrum antibacterial activity, including quinolone-resistant isolates, but suffer from potent hERG inhibition (IC(50)= 3 muM for 1). Carbon 71-77 ETS transcription factor ERG Homo sapiens 233-237 21900003-4 2011 To develop a highly selective amperometric biosensor for H(2)O(2) and iodate, the model enzyme catalase (CAT) was immobilized at CACNT modified glassy carbon electrode surface. Carbon 151-157 catalase Homo sapiens 95-103 21900003-4 2011 To develop a highly selective amperometric biosensor for H(2)O(2) and iodate, the model enzyme catalase (CAT) was immobilized at CACNT modified glassy carbon electrode surface. Carbon 151-157 catalase Homo sapiens 105-108 22023871-3 2011 The immobilization of VEGF-R1 on glassy carbon electrodes was carried out using layer-by-layer covalent attachment of VEGF-R1. Carbon 40-46 fms related receptor tyrosine kinase 1 Homo sapiens 22-29 22219843-1 2011 In the title polymer, [Cd(C(8)H(10)O(4))(H(2)O)(2)](n), the Cd(II) cation is coordinated by five carboxyl-ate O atoms from three different cyclo-hexane-1,2-dicarboxyl-ate anions and two O atoms from two water mol-ecules, displaying a distorted CdO(7) pentagonal-bipyramidal geometry. Carbon 23-24 cell adhesion associated, oncogene regulated Homo sapiens 244-247 21919174-0 2011 Dual role of S-adenosylmethionine (SAM+) in the methylation of sp2-hybridized electrophilic carbons. Carbon 92-99 Sp2 transcription factor Homo sapiens 63-66 22067167-0 2011 Carbon nanotube inhibits the formation of beta-sheet-rich oligomers of the Alzheimer"s amyloid-beta(16-22) peptide. Carbon 0-6 amyloid beta precursor protein Homo sapiens 87-99 22219946-1 2011 The title compound, C(35)H(35)NO(2) CH(4)O, was obtained by the reaction of rac-2-amino-2-hy-droxy-1,1-binaphthyl and 3,5-di-tert-butyl-2-hy-droxy-benzaldehyde in absolute methanol. Carbon 20-21 Rac family small GTPase 2 Homo sapiens 76-81 21909663-0 2011 Novel magnetic bovine serum albumin imprinted polymers with a matrix of carbon nanotubes, and their application to protein separation. Carbon 72-78 albumin Homo sapiens 22-35 21909663-1 2011 Novel magnetic multi-walled carbon nanotubes@Fe(3)O(4) molecularly imprinted polymers (MWNTs@Fe(3)O(4)-MIPs) intended for bovine serum albumin (BSA) recognition were successfully developed. Carbon 28-34 albumin Homo sapiens 129-142 21923110-0 2011 Aptamer biosensor based on fluorescence resonance energy transfer from upconverting phosphors to carbon nanoparticles for thrombin detection in human plasma. Carbon 97-103 coagulation factor II, thrombin Homo sapiens 122-130 21975067-2 2011 The endogenous PKC activator diacylglycerol contains two long carbon chains, which are attached to the glycerol moiety via ester linkage. Carbon 62-68 proline rich transmembrane protein 2 Homo sapiens 15-18 21908639-9 2011 Consistent with this, ALY2- and UBP13-engineered cells of the industrial QA23 strain grew faster and produced more CO2 at 12 C than did the parental when maltose was used as the sole carbon source. Carbon 183-189 Aly2p Saccharomyces cerevisiae S288C 22-26 21937154-1 2011 We recently discovered and reported a novel series of benzhydrylpiperazine derivatives bearing an asymmetric carbon atom that are potent and selective hCB1 inverse agonists. Carbon 109-115 cannabinoid receptor 1 Homo sapiens 151-155 21999734-8 2011 Apart from other interaction-types, six carbon atoms of CP (C1, C2, C3, C4, C6 and C7) were determined to be involved in hydrophobic interactions with amino acid residues Y121, W233, L323, F331, F335 and Y338 of the "acyl pocket" within AChE. Carbon 40-46 acetylcholinesterase (Cartwright blood group) Homo sapiens 237-241 21769686-4 2011 This phosphorylation inactivates flux of glycolysis-derived carbon through this enzyme complex and implicates the PDH regulatory kinases (PDKs) as a possible drug target. Carbon 60-66 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 114-117 21922082-0 2011 Combination of pi-pi stacking and electrostatic repulsion between carboxylic carbon nanoparticles and fluorescent oligonucleotides for rapid and sensitive detection of thrombin. Carbon 77-83 coagulation factor II, thrombin Homo sapiens 168-176 21665323-11 2011 We conclude that the LEC2 transcription factor not only controls cotyledon identity and morphology as previously reported, but also alters: (1) the delivery of photosynthates from the seed coat to the embryo (sink strength), (2) carbon partitioning towards different storage compounds (oil, proteins and carbohydrates), (3) the rate of starch synthesis and degradation in developing seeds and (4) germination capacity of dry seeds. Carbon 229-235 AP2/B3-like transcriptional factor family protein Arabidopsis thaliana 21-25 21948794-8 2011 C++ and Matlab code is available at http://www.ee.columbia.edu/~guido/BAMBI or http://genomics.lbl.gov/BAMBI/. Carbon 0-3 BMP and activin membrane bound inhibitor Homo sapiens 70-75 21948794-8 2011 C++ and Matlab code is available at http://www.ee.columbia.edu/~guido/BAMBI or http://genomics.lbl.gov/BAMBI/. Carbon 0-3 BMP and activin membrane bound inhibitor Homo sapiens 103-108 21802498-3 2011 Hydroxylation at the alpha-2 carbon position of the fatty acid is found in half the population of ST molecules. Carbon 29-35 glycoprotein hormone subunit alpha 2 Homo sapiens 21-28 22029707-3 2011 The formations of nanocrystalline graphite are observed on silicon dioxide and glass, while mainly sp2 amorphous carbons are formed on strontium titanate and yttria-stabilized zirconia. Carbon 113-120 Sp2 transcription factor Homo sapiens 99-102 21878621-11 2011 These results indicate that BHMT has an important role in Hcy, choline, and one-carbon homeostasis. Carbon 80-86 betaine-homocysteine methyltransferase Mus musculus 28-32 21962692-0 2011 A novel lable-free electrochemical immunosensor for carcinoembryonic antigen based on gold nanoparticles-thionine-reduced graphene oxide nanocomposite film modified glassy carbon electrode. Carbon 172-178 CEA cell adhesion molecule 3 Homo sapiens 52-76 22024416-0 2011 Robust control of PEP formation rate in the carbon fixation pathway of C(4) plants by a bi-functional enzyme. Carbon 44-50 phosphoenolpyruvate carboxylase 2 Zea mays 18-21 22024416-2 2011 We asked how PEP formation rate, a key step in the carbon fixation pathway, might work at a precise rate, regulated by light, despite fluctuations in substrate and enzyme levels constituting and regulating this process. Carbon 51-57 phosphoenolpyruvate carboxylase 2 Zea mays 13-16 22024416-3 2011 RESULTS: We present a putative mechanism for robustness in C(4) carbon fixation, involving a key enzyme in the pathway, pyruvate orthophosphate dikinase (PPDK), which is regulated by a bifunctional enzyme, Regulatory Protein (RP). Carbon 64-70 regulatory protein Zea mays 206-224 22024416-3 2011 RESULTS: We present a putative mechanism for robustness in C(4) carbon fixation, involving a key enzyme in the pathway, pyruvate orthophosphate dikinase (PPDK), which is regulated by a bifunctional enzyme, Regulatory Protein (RP). Carbon 64-70 regulatory protein Zea mays 226-228 21928852-0 2011 Intermolecular oxidative C-N bond formation under metal-free conditions: control of chemoselectivity between aryl sp2 and benzylic sp3 C-H bond imidation. Carbon 25-26 Sp2 transcription factor Homo sapiens 114-117 21928852-0 2011 Intermolecular oxidative C-N bond formation under metal-free conditions: control of chemoselectivity between aryl sp2 and benzylic sp3 C-H bond imidation. Carbon 25-26 Sp3 transcription factor Homo sapiens 131-134 21862579-4 2011 In this study, we found that LPS or poly(I:C)-induced TBK1 activity was significantly reduced in bone marrow-derived macrophage (BMDM) from OPTN(D477N/D477N) mice. Carbon 43-44 optineurin Mus musculus 140-144 21829823-1 2011 A simple and facile impedance immunoassay strategy for sensitive detection of alpha-fetoprotein (AFP), as a model cancer marker, was developed by using target-induced release of nanogold particle-labelled anti-AFP antibodies from polyvinylpyrrolidone-coated magnetic carbon nanotubes. Carbon 267-273 alpha fetoprotein Homo sapiens 78-95 21829823-1 2011 A simple and facile impedance immunoassay strategy for sensitive detection of alpha-fetoprotein (AFP), as a model cancer marker, was developed by using target-induced release of nanogold particle-labelled anti-AFP antibodies from polyvinylpyrrolidone-coated magnetic carbon nanotubes. Carbon 267-273 alpha fetoprotein Homo sapiens 97-100 21861293-2 2011 This study explores a novel therapy model with mitochondria-targeting single-walled carbon nanotubes (SWNTs), which act efficiently to convert 980-nm laser energy into heat and selectively destroy the target mitochondria, thereby inducing mitochondrial depolarization, cytochrome c release, and caspase 3 activation. Carbon 84-90 cytochrome c, somatic Homo sapiens 269-281 21861293-2 2011 This study explores a novel therapy model with mitochondria-targeting single-walled carbon nanotubes (SWNTs), which act efficiently to convert 980-nm laser energy into heat and selectively destroy the target mitochondria, thereby inducing mitochondrial depolarization, cytochrome c release, and caspase 3 activation. Carbon 84-90 caspase 3 Homo sapiens 295-304 21854032-8 2011 Moreover, a nanofilter based on the carbon films has shown an excellent size-selective filtration of cytochrome c and bovine serum albumin. Carbon 36-42 cytochrome c, somatic Homo sapiens 101-113 21708119-1 2011 A new electrochemical immunoassay of alpha-fetoprotein (AFP) was developed on an organic-inorganic hybrid nanostructure-functionalized carbon electrode by coupling with magnetic bionanolabels. Carbon 135-141 alpha fetoprotein Homo sapiens 37-54 21708119-1 2011 A new electrochemical immunoassay of alpha-fetoprotein (AFP) was developed on an organic-inorganic hybrid nanostructure-functionalized carbon electrode by coupling with magnetic bionanolabels. Carbon 135-141 alpha fetoprotein Homo sapiens 56-59 23761338-1 2011 Hypolithic microbial communities (i.e. cryptic microbial assemblages found on the undersides of translucent rocks) are major contributors of carbon input into the oligotrophic hyper-arid desert mineral soils of the Eastern Antarctic Dry Valleys. Carbon 141-147 cripto, FRL-1, cryptic family 1 Homo sapiens 39-46 21807091-6 2011 We observed a total of three carbon-centered radicals formed in 15-LOX-DPA (n-3) stemming from its 7-, 17-, and 20-hydroperoxides, whereas only one formed from 17-hydroperoxide in DPA (n-6). Carbon 29-35 arachidonate 15-lipoxygenase Homo sapiens 64-70 22263461-3 2011 In 2004-2013, the mean annual carbon sequestration potential of forest vegetation under natural growth in Jiangxi and Zhejiang could reach 11.37 and 4.34 Tg C a(-1) (1 Tg=10(12) g), respectively. Carbon 30-36 transglutaminase 2 Homo sapiens 154-158 22263461-4 2011 Interplanting could generate the largest carbon sequestration potential of forest vegetation, followed by selective thinning, and fertilization, resulting in an increase in the potential by (6.54 +/- 3.9) Tg C a(-1), (3.81 +/- 2.02) Tg C a(-1), and (2.35 +/- 0.6) Tg C a(-1) in Jiangxi and by (2.64 +/- 1.28) Tg C a(-1), (1.42 +/- 0.69) Tg C a(-1), and (1.15 +/- 0.29) Tg C a(-1) in Zhejiang, respectively. Carbon 41-47 transglutaminase 2 Homo sapiens 205-209 21872047-0 2011 One step electrochemically deposited nanocomposite film of chitosan-carbon nanotubes-gold nanoparticles for carcinoembryonic antigen immunosensor application. Carbon 68-74 CEA cell adhesion molecule 3 Homo sapiens 108-132 21818498-2 2011 The catalytic performances of the [Pd(NHC)(dvtms)] complexes are evaluated in the Mizoroki-Heck coupling of 4-bromoacetophenone and n-butyl acrylate, providing a ready and effective comparison into the influence of ring size and steric congestion on catalytic activity in carbon-carbon cross coupling reactions. Carbon 272-278 high mobility group nucleosomal binding domain 4 Homo sapiens 38-41 21818498-2 2011 The catalytic performances of the [Pd(NHC)(dvtms)] complexes are evaluated in the Mizoroki-Heck coupling of 4-bromoacetophenone and n-butyl acrylate, providing a ready and effective comparison into the influence of ring size and steric congestion on catalytic activity in carbon-carbon cross coupling reactions. Carbon 279-285 high mobility group nucleosomal binding domain 4 Homo sapiens 38-41 21800904-0 2011 Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism. Carbon 18-24 NLR family pyrin domain containing 3 Homo sapiens 61-66 21733626-0 2011 Taguchi optimization approach for Pb(II) and Hg(II) removal from aqueous solutions using modified mesoporous carbon. Carbon 109-115 submaxillary gland androgen regulated protein 3B Homo sapiens 34-40 21764754-2 2011 Using forest inventory data and long-term ecosystem carbon studies, we estimate a total forest sink of 2.4 +- 0.4 petagrams of carbon per year (Pg C year(-1)) globally for 1990 to 2007. Carbon 127-133 progastricsin Homo sapiens 144-148 21697465-9 2011 HSV-2 R1 inhibited the interaction between the Toll/interleukin-1 receptor domain-containing adaptor-inducing beta interferon (IFN-beta) (TRIF) and RIP1, an interaction that is essential for apoptosis triggered by extracellular poly(I C) plus cycloheximide or TRIF overexpression. Carbon 237-238 TIR domain containing adaptor molecule 1 Homo sapiens 138-142 21795582-7 2011 These results demonstrate that mutation of BRI1 can enhance photosynthesis and leaf growth/vascularization and may suggest new approaches to increase whole plant carbon assimilation and growth. Carbon 162-168 Leucine-rich receptor-like protein kinase family protein Arabidopsis thaliana 43-47 21761071-4 2011 As an application to a realistic protein, carbon chemical shifts are calculated for the retinal chromophore in visual rhodopsin. Carbon 42-48 rhodopsin Homo sapiens 118-127 21763268-0 2011 C-26 vs. C-27 hydroxylation of insect steroid hormones: regioselectivity of a microsomal cytochrome P450 from a hormone-resistant cell line. Carbon 0-1 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 89-104 21790145-10 2011 Preferential scavenging of water-soluble organic carbon (WSOC) by fog droplets was observed. Carbon 49-55 zinc finger protein, FOG family member 1 Homo sapiens 66-69 21809940-1 2011 Recent studies have shown that the stable carbon isotope compositions of dissolved inorganic carbon (delta(13)C(DIC)) of water samples preserved with HgCl(2) and CuSO(4) vary. Carbon 42-48 solute carrier family 25 member 10 Homo sapiens 112-115 21809940-1 2011 Recent studies have shown that the stable carbon isotope compositions of dissolved inorganic carbon (delta(13)C(DIC)) of water samples preserved with HgCl(2) and CuSO(4) vary. Carbon 93-99 solute carrier family 25 member 10 Homo sapiens 112-115 21755398-1 2011 This study reports the use of tetraethylene glycol-terminated self-assembled monolayers (EG(4) SAMs) as a background non-fouling surface to study the effect of an 18 carbon ligand (C18) on albumin selective and reversible adsorption and subsequent platelet and leukocyte adhesion. Carbon 166-172 Bardet-Biedl syndrome 9 Homo sapiens 181-184 21862853-2 2011 The carbon (C 1s) binding energy spectra of the aliphatic amino acids are derived from the C 1s spectrum of glycine (the parent spectrum) by the addition of spectral peaks, depending on the alkyl side chains, appearing in the lower energy region IP < 290 eV (where IP is the ionization potential). Carbon 4-10 complement C1s Homo sapiens 12-16 21862853-2 2011 The carbon (C 1s) binding energy spectra of the aliphatic amino acids are derived from the C 1s spectrum of glycine (the parent spectrum) by the addition of spectral peaks, depending on the alkyl side chains, appearing in the lower energy region IP < 290 eV (where IP is the ionization potential). Carbon 4-10 complement C1s Homo sapiens 91-95 22276430-7 2011 Moreover, both the point gsh1 and null gsh1/met1 mutants displayed increased sensitivity to the toxic carbon substrate methanol, formaldehyde, organic peroxide and cadmium ions. Carbon 102-108 glutamate--cysteine ligase Saccharomyces cerevisiae S288C 25-29 22276430-7 2011 Moreover, both the point gsh1 and null gsh1/met1 mutants displayed increased sensitivity to the toxic carbon substrate methanol, formaldehyde, organic peroxide and cadmium ions. Carbon 102-108 glutamate--cysteine ligase Saccharomyces cerevisiae S288C 39-43 21626688-0 2011 Quantification of uptake and localization of bovine serum albumin-stabilized single-wall carbon nanotubes in different human cell types. Carbon 89-95 albumin Homo sapiens 52-65 21764754-3 2011 We also estimate a source of 1.3 +- 0.7 Pg C year(-1) from tropical land-use change, consisting of a gross tropical deforestation emission of 2.9 +- 0.5 Pg C year(-1) partially compensated by a carbon sink in tropical forest regrowth of 1.6 +- 0.5 Pg C year(-1). Carbon 194-200 progastricsin Homo sapiens 40-44 21732642-1 2011 Electrochemical detection of p-nitrophenol (P-NP) using a highly sensitive and selective platform based on single-walled carbon nanotube/pyrenecyclodextrin (SWCNT/PyCD) nanohybrids is described for the first time. Carbon 121-127 purine nucleoside phosphorylase Homo sapiens 44-48 21732642-1 2011 Electrochemical detection of p-nitrophenol (P-NP) using a highly sensitive and selective platform based on single-walled carbon nanotube/pyrenecyclodextrin (SWCNT/PyCD) nanohybrids is described for the first time. Carbon 157-162 purine nucleoside phosphorylase Homo sapiens 44-48 21087810-16 2011 Although the biochemical function of HIP1.3 has not yet been elucidated, it is likely to possess an important function in the central carbon metabolism of higher plants. Carbon 134-140 HSP70-interacting protein 1 Arabidopsis thaliana 37-41 21401618-1 2011 The plant mitochondrial electron transport chain (ETC) includes a non-energy conserving alternative oxidase (AOX) thought to dampen reactive oxygen species (ROS) generation by the ETC and/or facilitate carbon metabolism by uncoupling it from ATP turnover. Carbon 202-208 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 88-107 21746787-15 2011 These data indicate that the increase in myofibrillar MPS for C+P could, potentially, be mediated through p70S6K, downstream of mTOR, which in turn may suppress the rise in eEF2 on translation elongation. Carbon 62-63 mechanistic target of rapamycin kinase Homo sapiens 128-132 22090917-1 2011 In the title complex, [Co(C(22)H(18)N(2)O(4))(CN)(H(2)O)] CH(3)CN, the Co(III) ion is six-coordinated in a distorted octa-hedral environment defined by two N atoms and two O atoms from a salen ligand in the equatorial plane and one O atom from a water mol-ecule and one C atom from a cyanide group at the axial positions. Carbon 23-24 mitochondrially encoded cytochrome c oxidase III Homo sapiens 71-78 22090917-1 2011 In the title complex, [Co(C(22)H(18)N(2)O(4))(CN)(H(2)O)] CH(3)CN, the Co(III) ion is six-coordinated in a distorted octa-hedral environment defined by two N atoms and two O atoms from a salen ligand in the equatorial plane and one O atom from a water mol-ecule and one C atom from a cyanide group at the axial positions. Carbon 26-27 mitochondrially encoded cytochrome c oxidase III Homo sapiens 71-78 21852536-3 2011 However, flux through pyruvate dehydrogenase (PDH) is disproportionally decreased, concomitant with increased expression of the PDH inhibitory kinase, PDH kinase 4 (PDK4), and increased carbon secretion. Carbon 186-192 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 22-44 21852536-3 2011 However, flux through pyruvate dehydrogenase (PDH) is disproportionally decreased, concomitant with increased expression of the PDH inhibitory kinase, PDH kinase 4 (PDK4), and increased carbon secretion. Carbon 186-192 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 46-49 21860602-16 2011 We found that only in human milk gangliosides was the ceramide carbon always even numbered, which is consistent with the notion that differences in the oligosaccharide and the ceramide moieties confer to their physiological distinctions. Carbon 63-69 Weaning weight-maternal milk Bos taurus 28-32 21401618-1 2011 The plant mitochondrial electron transport chain (ETC) includes a non-energy conserving alternative oxidase (AOX) thought to dampen reactive oxygen species (ROS) generation by the ETC and/or facilitate carbon metabolism by uncoupling it from ATP turnover. Carbon 202-208 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 109-112 21645691-0 2011 Acetylcholinesterase biosensor based on single-walled carbon nanotubes--Co phtalocyanine for organophosphorus pesticides detection. Carbon 54-60 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 21786998-3 2011 We introduce a forward convolution procedure to identify the portion of the signal, derived from the methyl image, which results from a two-step process in which C-Cl bond photofission is followed by the dissociation of the vibrationally excited CH(3)C(O)CH(2) radicals to CH(3) + COCH(2). Carbon 162-163 cochlin Homo sapiens 281-285 21621403-1 2011 A novel amperometric immunosensor for the detection of the p24 antigen (p24Ag) from HIV-1 was constructed using gold nanoparticles (GNP), multi-walled carbon nanotubes (MWCNTs), and an acetone-extracted propolis film (AEP). Carbon 151-157 transmembrane p24 trafficking protein 2 Homo sapiens 59-62 22097362-2 2011 The total carbon storage in the forest ecosystems was 1827.293 Tg C, and the carbon storages in arbor layer, shrub-grass layer, litter layer, and soil were 439.152 Tg C, 5.195 Tg C, 45.600 Tg C, and 1330.466 Tg C, accounting for 24.1%, 0.3%, 2.5%, and 73.1% of the total, respectively. Carbon 77-83 transglutaminase 2 Homo sapiens 164-168 22097362-2 2011 The total carbon storage in the forest ecosystems was 1827.293 Tg C, and the carbon storages in arbor layer, shrub-grass layer, litter layer, and soil were 439.152 Tg C, 5.195 Tg C, 45.600 Tg C, and 1330.466 Tg C, accounting for 24.1%, 0.3%, 2.5%, and 73.1% of the total, respectively. Carbon 77-83 transglutaminase 2 Homo sapiens 164-168 22097362-2 2011 The total carbon storage in the forest ecosystems was 1827.293 Tg C, and the carbon storages in arbor layer, shrub-grass layer, litter layer, and soil were 439.152 Tg C, 5.195 Tg C, 45.600 Tg C, and 1330.466 Tg C, accounting for 24.1%, 0.3%, 2.5%, and 73.1% of the total, respectively. Carbon 77-83 transglutaminase 2 Homo sapiens 164-168 22097362-2 2011 The total carbon storage in the forest ecosystems was 1827.293 Tg C, and the carbon storages in arbor layer, shrub-grass layer, litter layer, and soil were 439.152 Tg C, 5.195 Tg C, 45.600 Tg C, and 1330.466 Tg C, accounting for 24.1%, 0.3%, 2.5%, and 73.1% of the total, respectively. Carbon 77-83 transglutaminase 2 Homo sapiens 164-168 22097362-4 2011 Different types of the forest ecosystems had a carbon storage varied from 9.357 Tg C to 959.716 Tg C and a carbon density ranged from 180.648 Mg C * hm(-2) to 254.627 Mg C x hm(-2), with the highest values in soil and the lowest values in shrub-grass layer. Carbon 47-53 transglutaminase 2 Homo sapiens 80-84 21645691-1 2011 A simple and reliable technique has been developed for the construction of an amperometric acetylcholinesterase biosensor based on screen-printed carbon electrodes. Carbon 146-152 acetylcholinesterase (Cartwright blood group) Homo sapiens 91-111 21700028-1 2011 Pyruvate carboxylase (PC) is a critical enzyme in supplying carbon for gluconeogenesis and oxaloacetate for the tricarboxylic acid cycle. Carbon 60-66 pyruvate carboxylase Bos taurus 0-20 21836943-1 2011 In the title complex, [Co(C(10)H(6)O(2))(C(18)H(18)N(4))]PF(6) 0.5H(2)O, the Co(III) ion is six-coordinated in a distorted octa-hedral geometry by four N atoms from a tris-(2-pyridyl-meth-yl)amine ligand and two O atoms from a naphthalene-2,3-diolate ligand. Carbon 26-28 mitochondrially encoded cytochrome c oxidase III Homo sapiens 77-84 21396907-0 2011 Amperometric immunosensor for carcinoembryonic antigen detection with carbon nanotube-based film decorated with gold nanoclusters. Carbon 70-76 CEA cell adhesion molecule 3 Homo sapiens 30-54 21602385-0 2011 FadD19 of Rhodococcus rhodochrous DSM43269, a steroid-coenzyme A ligase essential for degradation of C-24 branched sterol side chains. Carbon 101-102 acyl-CoA synthetase Mycobacterium tuberculosis H37Rv 0-6 21602385-9 2011 Our data identified FadD19 as a steroid-coenzyme A (CoA) ligase with an essential in vivo role in the degradation of the side chains of C-24 branched-chain sterols. Carbon 52-53 acyl-CoA synthetase Mycobacterium tuberculosis H37Rv 20-26 22096994-0 2011 [Myeloperoxidase-induced biodegradation of single-walled carbon nanotubes is mediated by hypochlorite]. Carbon 57-63 myeloperoxidase Homo sapiens 1-16 22096994-4 2011 The comparison of the ability of various peroxidases to degrade SWNTs in vitro revealed that myeloperoxidase, due to its ability to produce hypochlorite, and lactoperoxidase, due to its ability to produce hypobromite, are extremely efficient in the degradation of carbon nanotubes. Carbon 264-270 myeloperoxidase Homo sapiens 93-108 21650175-3 2011 The milk metabolite profiles obtained by proton and carbon NMR spectroscopy could be correlated to breed and, more interestingly, also with the coagulation profile, as established by traditional methods by using principal component analysis (PCA). Carbon 52-58 Weaning weight-maternal milk Bos taurus 4-8 21690348-4 2011 Here, we studied whether silencing of Caspase-3 using carbon nanotube-mediated in vivo RNA interference (RNAi) could offer a therapeutic opportunity against stroke. Carbon 54-60 caspase 3 Homo sapiens 38-47 21690348-6 2011 It is shown here that peri-lesional stereotactic administration of a Caspase-3 siRNA (siCas 3) delivered by functionalized carbon nanotubes (f-CNT) reduced neurodegeneration and promoted functional preservation before and after focal ischemic damage of the rodent motor cortex using an endothelin-1 induced stroke model. Carbon 123-129 caspase 3 Homo sapiens 69-78 21953107-0 2011 A nano-chip-LC/MSn based strategy for characterization of modified nucleosides using reduced porous graphitic carbon as a stationary phase. Carbon 110-116 moesin Homo sapiens 15-18 21700028-1 2011 Pyruvate carboxylase (PC) is a critical enzyme in supplying carbon for gluconeogenesis and oxaloacetate for the tricarboxylic acid cycle. Carbon 60-66 pyruvate carboxylase Bos taurus 22-24 21576788-5 2011 The activation of the T lymphocyte response by the pro-inflammatory cytokines leads to an increase in antibody production to OVA, suggesting the important immunostimulatory effect of carbon nanotubes. Carbon 183-189 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 125-128 21418356-2 2011 In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation. Carbon 74-75 cytochrome p450 72c1 Arabidopsis thaliana 198-202 21421028-6 2011 Carbon black and small sized DEP generated from an Euro4 engine increased the surface expression of VCAM-1 and ICAM-1, whereas DEP from an engine representing an old combustion type engine (SRM2975) with larger particles did not affect the expression of cell adhesion molecules. Carbon 0-6 vascular cell adhesion molecule 1 Homo sapiens 100-106 21595480-0 2011 Steering carbon nanotubes to scavenger receptor recognition by nanotube surface chemistry modification partially alleviates NFkappaB activation and reduces its immunotoxicity. Carbon 9-15 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 124-132 21418356-2 2011 In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation. Carbon 74-75 cytochrome p450 72c1 Arabidopsis thaliana 180-187 21418356-2 2011 In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation. Carbon 74-75 cytochrome p450 72c1 Arabidopsis thaliana 188-192 21418356-2 2011 In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation. Carbon 74-75 cytochrome p450 72c1 Arabidopsis thaliana 193-197 21525001-6 2011 The cell death that occurred with carbon black nanoparticle exposure was identified as pyroptosis by the protective effect of a caspase 1 inhibitor and a pyroptosis inhibitor. Carbon 34-40 caspase 1 Homo sapiens 128-137 21461861-1 2011 In this study, a novel and enzyme-free electrochemical immunoassay was developed for the detection of alpha-fetoprotein (AFP; as a model biomarker) by using a novel redox nanocatalyst, patterned gold-iridium oxide nanoparticle assemblies (Au-IrO(x)), on a Prussian blue (PB) functionalized glassy carbon electrode. Carbon 297-303 alpha fetoprotein Homo sapiens 102-119 21660117-0 2011 Simultaneous Stripping Detection of Pb(II), Cd(II) and Zn(II) Using a Bimetallic Hg-Bi/Single-Walled Carbon Nanotubes Composite Electrode. Carbon 101-107 submaxillary gland androgen regulated protein 3B Homo sapiens 36-42 26295426-3 2011 The formation energy of hydroxyl pairs with graphene is coverage-dependent, and the most stable structure is half-covered by hydroxyl pairs along zigzag chains with alternative sp2 and sp3 hybridization between carbon atoms. Carbon 211-217 Sp3 transcription factor Homo sapiens 185-188 21461861-1 2011 In this study, a novel and enzyme-free electrochemical immunoassay was developed for the detection of alpha-fetoprotein (AFP; as a model biomarker) by using a novel redox nanocatalyst, patterned gold-iridium oxide nanoparticle assemblies (Au-IrO(x)), on a Prussian blue (PB) functionalized glassy carbon electrode. Carbon 297-303 alpha fetoprotein Homo sapiens 121-124 21538020-0 2011 ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse model of platyspondylic lethal skeletal dysplasia, Torrance type. Carbon 37-38 collagen, type II, alpha 1 Mus musculus 67-73 21384402-3 2011 AST-120, an oral adsorbent of engineered activated carbon microspheres with surface areas exceeding 1600 m2/g, acts as a sink for neurotoxins and hepatotoxins present in the gut. Carbon 51-57 solute carrier family 17 member 5 Homo sapiens 0-3 21470075-11 2011 In contrast, the hippocampal NR2A and NR2B levels significantly decreased in the NCR group compared with the C group (P < 0.05). Carbon 82-83 glutamate ionotropic receptor NMDA type subunit 2A Rattus norvegicus 29-33 21384402-0 2011 AST-120 (spherical carbon adsorbent) lowers ammonia levels and attenuates brain edema in bile duct-ligated rats. Carbon 19-25 solute carrier family 17 member 5 Homo sapiens 0-3 21499642-0 2011 Ice-mediated coating of macroporous cryogels by carbon nanotubes: a concept towards electrically conducting nanocomposites. Carbon 48-54 carboxylesterase 2 Homo sapiens 0-3 21602856-2 2011 These engineered nanostructures for organic electronics are based on conjugated systems predominantly made up of sp2-hybridized carbon, such as graphene nanoribbons. Carbon 128-134 Sp2 transcription factor Homo sapiens 113-116 21738477-8 2011 In vitro, the rrp1 mutant is impaired in growth in the media containing glycerol as the carbon source (BSK-glycerol). Carbon 88-94 ribosomal RNA processing 1 Homo sapiens 14-18 21376789-5 2011 The synthesis and characterization of novel materials, consisting of complexes between human transferrin and hydrophobic high-carbon-content compounds, is reported here for the first time. Carbon 126-132 transferrin Homo sapiens 93-104 21440431-0 2011 Mesoporous carbon microparticles as a novel fluorescent sensing platform for thrombin detection. Carbon 11-17 coagulation factor II, thrombin Homo sapiens 77-85 21639468-0 2011 Very-high-strength (60-GPa) carbon nanotube fiber design based on molecular dynamics simulations. Carbon 28-34 glycophorin A (MNS blood group) Homo sapiens 23-26 21461424-1 2011 Complexes [Cu(SPh)(2)](-), [Cu(SPh)I](-) and K[Cu(SPh)(2)(Ph)](+) were observed by in situ electrospray ionization mass spectrometry (ESI-MS) analysis of the copper(i)-catalyzed C-S coupling reaction under catalytic reaction conditions indicating that they are intermediates in the reaction. Carbon 0-1 surfactant associated 3 Homo sapiens 14-17 21461424-1 2011 Complexes [Cu(SPh)(2)](-), [Cu(SPh)I](-) and K[Cu(SPh)(2)(Ph)](+) were observed by in situ electrospray ionization mass spectrometry (ESI-MS) analysis of the copper(i)-catalyzed C-S coupling reaction under catalytic reaction conditions indicating that they are intermediates in the reaction. Carbon 0-1 surfactant associated 3 Homo sapiens 31-34 21461424-1 2011 Complexes [Cu(SPh)(2)](-), [Cu(SPh)I](-) and K[Cu(SPh)(2)(Ph)](+) were observed by in situ electrospray ionization mass spectrometry (ESI-MS) analysis of the copper(i)-catalyzed C-S coupling reaction under catalytic reaction conditions indicating that they are intermediates in the reaction. Carbon 0-1 surfactant associated 3 Homo sapiens 31-34 21593791-0 2011 A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt-TSC2-mTOR signaling. Carbon 31-37 AKT serine/threonine kinase 1 Homo sapiens 105-108 21593791-0 2011 A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt-TSC2-mTOR signaling. Carbon 31-37 mechanistic target of rapamycin kinase Homo sapiens 114-118 21352096-5 2011 The structural determinants revealed unique features of the binding of two molecules of the dual inhibitor in the active site of C-ACE. Carbon 129-130 angiotensin I converting enzyme Homo sapiens 131-134 21296186-7 2011 Expression of a human homolog of Coq8p, ADCK3(CABC1) bearing an amino-terminal yeast mitochondrial leader sequence, rescued growth of yeast coq8 mutants on medium containing a nonfermentable carbon source and partially restored biosynthesis of Q(6). Carbon 191-197 coenzyme Q8A Homo sapiens 33-38 21296186-7 2011 Expression of a human homolog of Coq8p, ADCK3(CABC1) bearing an amino-terminal yeast mitochondrial leader sequence, rescued growth of yeast coq8 mutants on medium containing a nonfermentable carbon source and partially restored biosynthesis of Q(6). Carbon 191-197 coenzyme Q8A Homo sapiens 40-45 21296186-7 2011 Expression of a human homolog of Coq8p, ADCK3(CABC1) bearing an amino-terminal yeast mitochondrial leader sequence, rescued growth of yeast coq8 mutants on medium containing a nonfermentable carbon source and partially restored biosynthesis of Q(6). Carbon 191-197 coenzyme Q8A Homo sapiens 46-51 21473574-0 2011 In situ measurement of PCB pore water concentration profiles in activated carbon-amended sediment using passive samplers. Carbon 74-80 pyruvate carboxylase Homo sapiens 23-26 21780424-0 2011 Apta-biosensors for nonlabeled real time detection of human IgE based on carbon nanotube field effect transistors. Carbon 73-79 immunoglobulin heavy constant epsilon Homo sapiens 60-63 21532885-6 2011 The P-selectin specificity of the STMC was defined by the anomeric linkage of the C-C bond. Carbon 37-38 selectin, platelet Mus musculus 4-14 21328367-7 2011 Snail tissues contain valuable concentrations of PUFA, especially n-6 and n-3 with chain lengths of 20 and 22 carbons. Carbon 110-117 snail family transcriptional repressor 1 Homo sapiens 0-5 21094255-3 2011 Certain members of the P-450 family, including CYP17 and CYP19, catalyze, at the same active site, not only the hydroxylation process but also an acyl-carbon bond cleavage reaction which has been interpreted to involve the nucleophilic attack of the ferric-peroxyanion, Fe(III)-O-O(-), on the acyl carbon to furnish a tetrahedral intermediate which fragments, leading to acyl-carbon cleavage. Carbon 151-157 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 57-62 21094255-3 2011 Certain members of the P-450 family, including CYP17 and CYP19, catalyze, at the same active site, not only the hydroxylation process but also an acyl-carbon bond cleavage reaction which has been interpreted to involve the nucleophilic attack of the ferric-peroxyanion, Fe(III)-O-O(-), on the acyl carbon to furnish a tetrahedral intermediate which fragments, leading to acyl-carbon cleavage. Carbon 298-304 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 57-62 21094255-3 2011 Certain members of the P-450 family, including CYP17 and CYP19, catalyze, at the same active site, not only the hydroxylation process but also an acyl-carbon bond cleavage reaction which has been interpreted to involve the nucleophilic attack of the ferric-peroxyanion, Fe(III)-O-O(-), on the acyl carbon to furnish a tetrahedral intermediate which fragments, leading to acyl-carbon cleavage. Carbon 298-304 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 57-62 21532885-6 2011 The P-selectin specificity of the STMC was defined by the anomeric linkage of the C-C bond. Carbon 82-83 selectin, platelet Mus musculus 4-14 21501720-1 2011 A new sandwich-type electrochemical immunosensor with enhanced sensitivity was developed for detection of alpha-fetoprotein (AFP, as a model analyte) in biological fluids by using nanogold-enclosed titania nanoparticle (AuTi)-labeled secondary antibody on a gold-silver-graphene hybrid nanosheet (AuAgGP)-functionalized glassy carbon electrode (GCE). Carbon 327-333 alpha fetoprotein Homo sapiens 106-123 21326122-1 2011 OBJECTIVE: The aim of this study was to investigate the clinical value of 3"-deoxy-3"-[F]fluorothymidine-positron emission tomography/computed tomography (FLT-PET/CT) for lung cancer patients receiving carbon-ion radiotherapy. Carbon 202-208 fms related receptor tyrosine kinase 1 Homo sapiens 155-158 21326122-10 2011 Kaplan-Meier analysis using a cut-off value also supported the prognostic value of pre-carbon-ion radiotherapy FLT-PET/CT. Carbon 87-93 fms related receptor tyrosine kinase 1 Homo sapiens 111-114 21326122-11 2011 CONCLUSION: This investigation suggests that FLT-PET/CT is feasible in evaluating lung cancer patients undergoing carbon-ion radiotherapy. Carbon 114-120 fms related receptor tyrosine kinase 1 Homo sapiens 45-48 21326122-13 2011 Pre-carbon-ion radiotherapy FLT-PET/CT seems to have a prognostic value and may contribute to decision-making on the treatment strategy. Carbon 4-10 fms related receptor tyrosine kinase 1 Homo sapiens 28-31 21239147-6 2011 The 2D plot of PC2 vs. PC1 showed adequate separation of the CH(3), CH(2), CH and C cases (C stands for carbons without adjacent hydrogens). Carbon 104-111 polycystin 2, transient receptor potential cation channel Homo sapiens 15-18 21239147-6 2011 The 2D plot of PC2 vs. PC1 showed adequate separation of the CH(3), CH(2), CH and C cases (C stands for carbons without adjacent hydrogens). Carbon 104-111 ectonucleotide pyrophosphatase/phosphodiesterase 1 Homo sapiens 23-26 21501720-1 2011 A new sandwich-type electrochemical immunosensor with enhanced sensitivity was developed for detection of alpha-fetoprotein (AFP, as a model analyte) in biological fluids by using nanogold-enclosed titania nanoparticle (AuTi)-labeled secondary antibody on a gold-silver-graphene hybrid nanosheet (AuAgGP)-functionalized glassy carbon electrode (GCE). Carbon 327-333 alpha fetoprotein Homo sapiens 125-128 21377346-0 2011 A novel, sensitive, reusable and low potential acetylcholinesterase biosensor for chlorpyrifos based on 1-butyl-3-methylimidazolium tetrafluoroborate/multiwalled carbon nanotubes gel. Carbon 162-168 acetylcholinesterase (Cartwright blood group) Homo sapiens 47-67 21377346-1 2011 A novel, low potential and highly sensitive acetylcholinesterase (AChE) biosensor was developed based on 1-butyl-3-methylimidazolium tetrafluoroborate/multiwalled carbon nanotube composite gel thiocholine sensor. Carbon 163-169 acetylcholinesterase (Cartwright blood group) Homo sapiens 44-64 21377346-1 2011 A novel, low potential and highly sensitive acetylcholinesterase (AChE) biosensor was developed based on 1-butyl-3-methylimidazolium tetrafluoroborate/multiwalled carbon nanotube composite gel thiocholine sensor. Carbon 163-169 acetylcholinesterase (Cartwright blood group) Homo sapiens 66-70 21456701-2 2011 Motivated by the many nanoengineering applications of protein-carbon nanotube hybrids, we investigate the conformational transitions of hen egg white lysozyme adsorbed on a carbon nanotube. Carbon 173-179 lysozyme Homo sapiens 150-158 21222514-0 2011 Carbon-ion-induced activation of the NF-kappaB pathway. Carbon 0-6 nuclear factor kappa B subunit 1 Homo sapiens 37-46 21222514-5 2011 Therefore, activation of the NF-kappaB pathway by accelerated carbon ions (LET 33 and 73 keV/microm) was examined. Carbon 62-68 nuclear factor kappa B subunit 1 Homo sapiens 29-38 21222514-8 2011 Carbon ions and X rays had a comparable potential to activate NF-kappaB in human cells, indicating a comparable usefulness of pharmacological NF-kappaB inhibition during photon and carbon-ion radiotherapy. Carbon 0-6 nuclear factor kappa B subunit 1 Homo sapiens 62-71 21222514-8 2011 Carbon ions and X rays had a comparable potential to activate NF-kappaB in human cells, indicating a comparable usefulness of pharmacological NF-kappaB inhibition during photon and carbon-ion radiotherapy. Carbon 0-6 nuclear factor kappa B subunit 1 Homo sapiens 142-151 21395259-1 2011 This paper examines the adsorption of Pb(II) and a natural organic macromolecular compound (humic acid, HA) on polyacrylamide (PAAM) -grafted multiwalled carbon nanotubes (denoted as MWCNTs/PAAM), prepared by an N(2)-plasma-induced grafting technique. Carbon 154-160 submaxillary gland androgen regulated protein 3B Homo sapiens 38-44 21376985-0 2011 Carbon nanotube-based symbiotic coaxial nanocables with nanosilica and nanogold particles as labels for electrochemical immunoassay of carcinoembryonic antigen in biological fluids. Carbon 0-6 CEA cell adhesion molecule 3 Homo sapiens 135-159 21376985-1 2011 A feasible and practicable amperometric immunoassay strategy for sensitive screening of carcinoembryonic antigen (CEA) in human serum was developed using carbon nanotube (CNT)-based symbiotic coaxial nanocables as labels. Carbon 154-160 CEA cell adhesion molecule 3 Homo sapiens 88-112 21376985-1 2011 A feasible and practicable amperometric immunoassay strategy for sensitive screening of carcinoembryonic antigen (CEA) in human serum was developed using carbon nanotube (CNT)-based symbiotic coaxial nanocables as labels. Carbon 154-160 CEA cell adhesion molecule 3 Homo sapiens 114-117 21236332-10 2011 We conclude that the electrophilic carbon atom of 15d-PGJ(2) is responsible for alterations in intracellular redox status and Cox-2 expression. Carbon 35-41 prostaglandin-endoperoxide synthase 2 Homo sapiens 126-131 21237683-4 2011 ACAD11 utilizes substrates with primary carbon chain lengths between 20 and 26, with optimal activity towards C22CoA. Carbon 40-46 acyl-CoA dehydrogenase family member 11 Homo sapiens 0-6 21365724-0 2011 Carbon-catalyzed oxidative dehydrogenation of n-butane: selective site formation during sp3-to-sp2 lattice rearrangement. Carbon 0-6 Sp3 transcription factor Homo sapiens 88-91 21365724-0 2011 Carbon-catalyzed oxidative dehydrogenation of n-butane: selective site formation during sp3-to-sp2 lattice rearrangement. Carbon 0-6 Sp2 transcription factor Homo sapiens 95-98 21210027-0 2011 Carbon-supported Pt^Ag nanostructures as cathode catalysts for oxygen reduction reaction. Carbon 0-6 rhomboid domain containing 3 Homo sapiens 17-22 21216587-1 2011 A novel enzyme-free sandwich electrochemical immunoassay with an ultrahigh sensitivity was developed for detection of alpha-fetoprotein (AFP, as a model analyte) using carbon nanotube-enriched gold nanoparticles (CNT-AuNPs) as nanolabels/nanocatalysts on anti-AFP/glutaraldehyde/thionine-modified glassy carbon electrodes (GCEs). Carbon 168-174 alpha fetoprotein Homo sapiens 118-135 21216587-1 2011 A novel enzyme-free sandwich electrochemical immunoassay with an ultrahigh sensitivity was developed for detection of alpha-fetoprotein (AFP, as a model analyte) using carbon nanotube-enriched gold nanoparticles (CNT-AuNPs) as nanolabels/nanocatalysts on anti-AFP/glutaraldehyde/thionine-modified glassy carbon electrodes (GCEs). Carbon 168-174 alpha fetoprotein Homo sapiens 137-140 21216587-1 2011 A novel enzyme-free sandwich electrochemical immunoassay with an ultrahigh sensitivity was developed for detection of alpha-fetoprotein (AFP, as a model analyte) using carbon nanotube-enriched gold nanoparticles (CNT-AuNPs) as nanolabels/nanocatalysts on anti-AFP/glutaraldehyde/thionine-modified glassy carbon electrodes (GCEs). Carbon 168-174 alpha fetoprotein Homo sapiens 260-263 21469806-2 2011 Here, using electron irradiation we create an sp2-hybridized one-atom-thick flat carbon membrane with a random arrangement of polygons, including four-membered carbon rings. Carbon 81-87 Sp2 transcription factor Homo sapiens 46-49 21469806-2 2011 Here, using electron irradiation we create an sp2-hybridized one-atom-thick flat carbon membrane with a random arrangement of polygons, including four-membered carbon rings. Carbon 160-166 Sp2 transcription factor Homo sapiens 46-49 21234471-1 2011 A simple and efficient post-labeling strategy based on dye-induced peeling of the aptamer molecules off single-walled carbon nanotubes was developed for electrochemical aptasensing of thrombin with a detection limit down to 3 pM. Carbon 118-124 coagulation factor II, thrombin Homo sapiens 184-192 21262957-0 2011 AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia. Carbon 75-81 AKT serine/threonine kinase 1 Homo sapiens 9-12 21275419-5 2011 The observed changes suggest a decreased activity of the one carbon metabolism in pept-1(lg601) mutants. Carbon 61-67 Peptide transporter family 1 Caenorhabditis elegans 82-88 21170474-5 2011 We have functionally characterized six HNF1A mutations identified in diabetic patients: two novel ones, p.Glu235Gly and c-57-64delCACGCGGT;c-55G>C; and four previously described, p.Val133Met, p.Thr196Ala, p.Arg271Trp and p.Pro379Arg. Carbon 11-12 HNF1 homeobox A Homo sapiens 39-44 21170474-5 2011 We have functionally characterized six HNF1A mutations identified in diabetic patients: two novel ones, p.Glu235Gly and c-57-64delCACGCGGT;c-55G>C; and four previously described, p.Val133Met, p.Thr196Ala, p.Arg271Trp and p.Pro379Arg. Carbon 21-22 HNF1 homeobox A Homo sapiens 39-44 20972222-4 2011 Recently, we identified a novel Jumonji C (JmjC)-domain-containing protein, TYW5 (tRNA yW-synthesizing enzyme 5), which forms the OHyW nucleoside by carbon hydroxylation, using Fe(II) ion and 2-oxoglutarate (2-OG) as cofactors. Carbon 149-155 tRNA-yW synthesizing protein 5 Homo sapiens 76-80 20972222-4 2011 Recently, we identified a novel Jumonji C (JmjC)-domain-containing protein, TYW5 (tRNA yW-synthesizing enzyme 5), which forms the OHyW nucleoside by carbon hydroxylation, using Fe(II) ion and 2-oxoglutarate (2-OG) as cofactors. Carbon 149-155 tRNA-yW synthesizing protein 5 Homo sapiens 82-111 21163906-3 2011 A structure-activity relationship for PFAAs was observed, where eight to ten fluorinated carbons and a carboxylic acid end group were optimal for maximal Vtg induction. Carbon 89-96 putative uncharacterized protein LOC400499 Homo sapiens 154-157 21405524-0 2011 Low-temperature phase transformation from graphite to sp3 orthorhombic carbon. Carbon 71-77 Sp3 transcription factor Homo sapiens 54-57 21152621-0 2011 Combing DNAzyme with single-walled carbon nanotubes for detection of Pb(II) in water. Carbon 35-41 submaxillary gland androgen regulated protein 3B Homo sapiens 69-75 20843633-7 2011 Increasing carbon chain length of straight chain alcohols positively correlated with their ability to inhibit detection of tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10), but not with the detection of interleukin 6 (IL-6), interleukin 8, (IL-8), and interleukin 12 (IL-12). Carbon 11-17 tumor necrosis factor Homo sapiens 123-150 21185714-1 2011 A three-step electrodeposition method has been successfully adopted to fabricate morphology-controlled novel Au microspheres on self-doped polyaniline nanofibers (nanoSPAN) modified glassy carbon electrode. Carbon 189-195 sarcospan Homo sapiens 163-171 20843633-7 2011 Increasing carbon chain length of straight chain alcohols positively correlated with their ability to inhibit detection of tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10), but not with the detection of interleukin 6 (IL-6), interleukin 8, (IL-8), and interleukin 12 (IL-12). Carbon 11-17 tumor necrosis factor Homo sapiens 152-161 20843633-7 2011 Increasing carbon chain length of straight chain alcohols positively correlated with their ability to inhibit detection of tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10), but not with the detection of interleukin 6 (IL-6), interleukin 8, (IL-8), and interleukin 12 (IL-12). Carbon 11-17 interleukin 6 Homo sapiens 236-240 20843633-7 2011 Increasing carbon chain length of straight chain alcohols positively correlated with their ability to inhibit detection of tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10), but not with the detection of interleukin 6 (IL-6), interleukin 8, (IL-8), and interleukin 12 (IL-12). Carbon 11-17 C-X-C motif chemokine ligand 8 Homo sapiens 243-256 20843633-7 2011 Increasing carbon chain length of straight chain alcohols positively correlated with their ability to inhibit detection of tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10), but not with the detection of interleukin 6 (IL-6), interleukin 8, (IL-8), and interleukin 12 (IL-12). Carbon 11-17 C-X-C motif chemokine ligand 8 Homo sapiens 259-263 21056768-10 2011 Together all these results indicate that PL production in the bacilli studied is modulated by the growth phase and by the carbon source present in the medium. Carbon 122-128 pectate lyase Theobroma cacao 41-43 21207953-1 2011 We report here a carbon nanotube-based approach for label-free and time-resolved luminescent assay of lysozyme (LYS) by engineering an antilysozyme aptamer and luminescent europium(III) (Eu(3+)) complex. Carbon 17-23 lysozyme Homo sapiens 102-110 21232955-3 2011 Compound 1, characterized by the presence of a C-16/C-17, C-20/C-21 conjugated diene and a C-1/C-7 ester bridge formed in rings A and B, provided a novel structural skeleton for 3,4-secocycloartane triterpenoid derivatives. Carbon 0-1 TBL1X/Y related 1 Homo sapiens 63-67 21232955-3 2011 Compound 1, characterized by the presence of a C-16/C-17, C-20/C-21 conjugated diene and a C-1/C-7 ester bridge formed in rings A and B, provided a novel structural skeleton for 3,4-secocycloartane triterpenoid derivatives. Carbon 0-1 homeobox B7 Homo sapiens 91-98 21232955-3 2011 Compound 1, characterized by the presence of a C-16/C-17, C-20/C-21 conjugated diene and a C-1/C-7 ester bridge formed in rings A and B, provided a novel structural skeleton for 3,4-secocycloartane triterpenoid derivatives. Carbon 47-48 TBL1X/Y related 1 Homo sapiens 63-67 21456131-1 2011 The poly(L-Arginine)(PArg)-multiwalled carbon nanotubes (MWCNTs) composite film was used to modify glassy carbon electrode (GCE) to fabricate PArg/MWCNTs/GCE through electropolymerization of L-Arginine on MWCNTs/GCE. Carbon 39-45 poly(ADP-ribose) glycohydrolase Homo sapiens 21-25 21456131-1 2011 The poly(L-Arginine)(PArg)-multiwalled carbon nanotubes (MWCNTs) composite film was used to modify glassy carbon electrode (GCE) to fabricate PArg/MWCNTs/GCE through electropolymerization of L-Arginine on MWCNTs/GCE. Carbon 106-112 poly(ADP-ribose) glycohydrolase Homo sapiens 21-25 21456131-1 2011 The poly(L-Arginine)(PArg)-multiwalled carbon nanotubes (MWCNTs) composite film was used to modify glassy carbon electrode (GCE) to fabricate PArg/MWCNTs/GCE through electropolymerization of L-Arginine on MWCNTs/GCE. Carbon 39-45 poly(ADP-ribose) glycohydrolase Homo sapiens 142-146 21456131-1 2011 The poly(L-Arginine)(PArg)-multiwalled carbon nanotubes (MWCNTs) composite film was used to modify glassy carbon electrode (GCE) to fabricate PArg/MWCNTs/GCE through electropolymerization of L-Arginine on MWCNTs/GCE. Carbon 106-112 poly(ADP-ribose) glycohydrolase Homo sapiens 142-146 21061404-0 2011 Fibronectin-carbon-nanotube hybrid nanostructures for controlled cell growth. Carbon 12-18 fibronectin 1 Homo sapiens 0-11 20378330-4 2011 Biocompatible polyaniline doped with poly (acrylic acid) was electro-polymerized at the glass carbon electrode to construct the matrix for the immobilization of antibody TNF-alpha. Carbon 94-100 tumor necrosis factor Homo sapiens 170-179 21141967-1 2011 The first example of C-24 and C-23 sulfated sterols from a marine source endowed with a PXR agonistic activity. Carbon 21-22 nuclear receptor subfamily 1 group I member 2 Homo sapiens 88-91 21141967-1 2011 The first example of C-24 and C-23 sulfated sterols from a marine source endowed with a PXR agonistic activity. Carbon 30-31 nuclear receptor subfamily 1 group I member 2 Homo sapiens 88-91 21522824-1 2011 In the title coordination polymer, [Co(C(14)H(16)O(6))(H(2)O)(2)](n), the Co(II) ion, situated on a twofold rotation axis, is coordinated by four O atoms from two 4,4"-[1,4-phenyl-enebis(-oxy)]dibutano-ate (L) ligands and two water mol-ecules in a highly distorted octa-hedral geometry. Carbon 36-37 mitochondrially encoded cytochrome c oxidase II Homo sapiens 74-80 21072431-0 2011 Electrochemical sensing for caspase 3 activity and inhibition using quantum dot functionalized carbon nanotube labels. Carbon 95-101 caspase 3 Homo sapiens 28-37 21168546-2 2011 The enzyme cytochrome P450 was covalently attached to screen-printed carbon electrodes. Carbon 69-75 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 11-26 21289990-0 2011 Enhanced laser thermal ablation for the in vitro treatment of liver cancer by specific delivery of multiwalled carbon nanotubes functionalized with human serum albumin. Carbon 111-117 albumin Homo sapiens 154-167 21289990-2 2011 We present a method of carbon nanotube-enhanced laser thermal ablation of HepG2 cells (human hepatocellular liver carcinoma cell line) based on a simple multiwalled carbon nanotube (MWCNT) carrier system, such as human serum albumin (HSA), and demonstrate its selective therapeutic efficacy compared with normal hepatocyte cells. Carbon 23-29 albumin Homo sapiens 219-232 21168332-1 2011 We designed and synthesized a new class of (13)C-labeled NMR probe, (13)C-IQ-Gd, to monitor one-electron reductions by cytochrome:P450 (CYP450) reductase under hypoxic conditions. Carbon 47-48 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 119-134 21168332-1 2011 We designed and synthesized a new class of (13)C-labeled NMR probe, (13)C-IQ-Gd, to monitor one-electron reductions by cytochrome:P450 (CYP450) reductase under hypoxic conditions. Carbon 47-48 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 136-142 21084189-2 2011 Structure-activity relationship analysis demonstrated that insertion of C(6)H(5)- and 4-CH(3)C(6)H(4)- at position 4 for both classes and less bulkier aromatic group at position 1 in class 1 contribute critically to the modest Src inhibition activity (IC(50) = 32-43 muM) of 1,4-disubstituted 1,2,3-triazoles. Carbon 72-73 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 227-230 21628884-8 2011 These results suggest (i) that PFCAs with a chain length of 6-9 carbons change the fatty acid profile of hepatic lipids by increasing contents and proportions of 16 : 1, 18 : 1 and 20 : 3, (ii) that these alterations in fatty acid profile are caused by up-regulation of SCD, de novo fatty acid synthesis, chain elongase and Delta6 desaturase and (iii) that the mechanism underlying SCD induction is, in part, mediated through peroxisome proliferator-activated receptor alpha. Carbon 64-71 peroxisome proliferator activated receptor alpha Mus musculus 426-474 21084189-2 2011 Structure-activity relationship analysis demonstrated that insertion of C(6)H(5)- and 4-CH(3)C(6)H(4)- at position 4 for both classes and less bulkier aromatic group at position 1 in class 1 contribute critically to the modest Src inhibition activity (IC(50) = 32-43 muM) of 1,4-disubstituted 1,2,3-triazoles. Carbon 72-73 latexin Homo sapiens 267-270 21737940-4 2011 Suppression of IL-6 secretion by smaller sized CS-A was stronger than that by intact CS-A, whereas no such size-dependent suppression was apparent for CS-C. Carbon 47-48 interleukin 6 Mus musculus 15-19 22105806-7 2011 Additionally, decreased Erk signaling in matrix-detached cells causes a disproportionate decrease in flux through pyruvate dehydrogenase (PDH), leading to decreased entry of glucose carbons into the citric acid cycle. Carbon 182-189 mitogen-activated protein kinase 1 Homo sapiens 24-27 21802664-4 2011 Neutralization of IFN-gamma blocks poly I:C plus inflammatory cytokines-induced NK cell TRAIL expression, suggesting that IFN-gamma is an autocrine differentiation factor for these cells. Carbon 42-43 interferon gamma Homo sapiens 18-27 21802664-4 2011 Neutralization of IFN-gamma blocks poly I:C plus inflammatory cytokines-induced NK cell TRAIL expression, suggesting that IFN-gamma is an autocrine differentiation factor for these cells. Carbon 42-43 interferon gamma Homo sapiens 122-131 25324899-4 2011 It is caused by a mutation in the elongation of very-long-chain fatty acids-like 4 (ELOVL4) gene, which is responsible for encoding the elongase enzyme that converts shorter chain fatty acids into C28-C38 very long-chain polyunsaturated fatty acids (VLCPUFAs, total number of carbons >=24). Carbon 276-283 ELOVL fatty acid elongase 4 Homo sapiens 34-82 25324899-4 2011 It is caused by a mutation in the elongation of very-long-chain fatty acids-like 4 (ELOVL4) gene, which is responsible for encoding the elongase enzyme that converts shorter chain fatty acids into C28-C38 very long-chain polyunsaturated fatty acids (VLCPUFAs, total number of carbons >=24). Carbon 276-283 ELOVL fatty acid elongase 4 Homo sapiens 84-90 22105806-7 2011 Additionally, decreased Erk signaling in matrix-detached cells causes a disproportionate decrease in flux through pyruvate dehydrogenase (PDH), leading to decreased entry of glucose carbons into the citric acid cycle. Carbon 182-189 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 114-136 22105806-7 2011 Additionally, decreased Erk signaling in matrix-detached cells causes a disproportionate decrease in flux through pyruvate dehydrogenase (PDH), leading to decreased entry of glucose carbons into the citric acid cycle. Carbon 182-189 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 138-141 20737426-8 2011 Exposure to carboxylated functionalized SWCNT induced ROS and enhanced the activities of serum amino-transferases (ALT/AST) and alkaline phosphatases (ALP) and the concentration of lipid hydroperoxide compared with control. Carbon 40-45 transmembrane protease, serine 11d Mus musculus 119-122 21428077-0 2011 [Studies on the interaction of gatifloxacin with bovine serum albumin in the presence of carbon nanotubes by fluorescence spectroscopy]. Carbon 89-95 albumin Homo sapiens 56-69 21102340-1 2011 The tumor marker carcinoembryonic antigen (CEA) was investigated using a graphite pencil electrode (PE) and fluorine immobilized onto a graphite pencil carbon electrode (FPE). Carbon 152-158 CEA cell adhesion molecule 3 Homo sapiens 4-47 21647289-0 2011 Evaluation of acetylcholinesterase biosensor based on carbon nanotube paste in the determination of chlorphenvinphos. Carbon 54-60 acetylcholinesterase (Cartwright blood group) Homo sapiens 14-34 22013390-1 2011 One novel electrochemical immunosensor was constructed by immobilizing capture antibody of alpha-fetoprotein (AFP Ab(1)) on a nafion/nanogold-particle modified glassy carbon electrode. Carbon 167-173 alpha fetoprotein Homo sapiens 91-108 22013390-1 2011 One novel electrochemical immunosensor was constructed by immobilizing capture antibody of alpha-fetoprotein (AFP Ab(1)) on a nafion/nanogold-particle modified glassy carbon electrode. Carbon 167-173 alpha fetoprotein Homo sapiens 110-113 21275261-3 2011 In the present study we tested the hypothesis that the functional status of p53 in tumour cells might have an impact on the efficiency of C-1305 in experiments with both p53-deficient human HL-60 promyelocytic leukemia cells and human MCF-7 breast cancer cells harboring a functional p53 pathway. Carbon 138-139 tumor protein p53 Homo sapiens 76-79 21942388-3 2011 The adsorption kinetics of single-walled carbon nanotubes (SWCNTs) was investigated in the presence of DOM as a possible technique for the pretreatment of DBP precursors. Carbon 41-47 D-box binding PAR bZIP transcription factor Homo sapiens 155-158 21110064-6 2011 Unlike the conventional HNCA experiment, which contains only sequential information to the 13C(alpha) of the preceding residue, the 3D hnCA-TOCSY-caNH experiment can yield sequential correlations to alpha carbons in positions i-1, i + 1 and i-2. Carbon 205-212 protein phosphatase 1 regulatory inhibitor subunit 1A Homo sapiens 226-229 21275261-3 2011 In the present study we tested the hypothesis that the functional status of p53 in tumour cells might have an impact on the efficiency of C-1305 in experiments with both p53-deficient human HL-60 promyelocytic leukemia cells and human MCF-7 breast cancer cells harboring a functional p53 pathway. Carbon 138-139 tumor protein p53 Homo sapiens 170-173 21275261-3 2011 In the present study we tested the hypothesis that the functional status of p53 in tumour cells might have an impact on the efficiency of C-1305 in experiments with both p53-deficient human HL-60 promyelocytic leukemia cells and human MCF-7 breast cancer cells harboring a functional p53 pathway. Carbon 138-139 tumor protein p53 Homo sapiens 170-173 21275261-9 2011 These observations suggest that C-1305 abrogates the restriction checkpoint and promotes G1/S transition in cells lacking functional p53. Carbon 32-33 tumor protein p53 Homo sapiens 133-136 21343675-0 2011 Carbon ion irradiation suppresses metastatic potential of human non-small cell lung cancer A549 cells through the phosphatidylinositol-3-kinase/Akt signaling pathway. Carbon 0-6 AKT serine/threonine kinase 1 Homo sapiens 144-147 21515944-5 2011 Following exposure to high-LET carbon ions, a reduced clonogenic survival effect, increased apoptotic rates and caspase-3 activity were observed in the cells treated with the siRNA compared to those untreated with the siRNA. Carbon 31-37 caspase 3 Homo sapiens 112-121 21343675-1 2011 We previously showed that carbon ion irradiation can inhibit the expression of the anillin (ANLN) gene, which is regulated by the activation of the phosphatidylinositol-3-kinase (PI3K)/Akt signaling pathway associated with metastasis. Carbon 26-32 AKT serine/threonine kinase 1 Homo sapiens 185-188 21343675-2 2011 The purpose of this study is to compare the effects of carbon ion irradiation on the PI3K/Akt signaling pathway to those of photon irradiation. Carbon 55-61 AKT serine/threonine kinase 1 Homo sapiens 90-93 21343675-5 2011 Low-dose carbon ion irradiation also reduced the level of phosphorylated Akt compared to untreated controls, whereas photon irradiation did not. Carbon 9-15 AKT serine/threonine kinase 1 Homo sapiens 73-76 21343675-6 2011 These results suggest that carbon ion irradiation effectively suppresses the metastatic potential of A549 cells by suppressing the PI3K/Akt signaling pathway. Carbon 27-33 AKT serine/threonine kinase 1 Homo sapiens 136-139 22073207-0 2011 Carbon dynamics, development and stress responses in Arabidopsis: involvement of the APL4 subunit of ADP-glucose pyrophosphorylase (starch synthesis). Carbon 0-6 Glucose-1-phosphate adenylyltransferase family protein Arabidopsis thaliana 85-89 21916701-0 2011 Promoter methylation of E-cadherin, p16, and RAR-beta(2) genes in breast tumors and dietary intake of nutrients important in one-carbon metabolism. Carbon 129-135 cadherin 1 Homo sapiens 24-34 22073207-4 2011 The resulting tissue-specific modifications of carbon partitioning in plantlets and the effects on plantlet growth and stress tolerance point out to specific and non-redundant roles of APL4 in root carbon dynamics, shoot-root relationships and sink regulations of photosynthesis. Carbon 47-53 Glucose-1-phosphate adenylyltransferase family protein Arabidopsis thaliana 185-189 22073207-4 2011 The resulting tissue-specific modifications of carbon partitioning in plantlets and the effects on plantlet growth and stress tolerance point out to specific and non-redundant roles of APL4 in root carbon dynamics, shoot-root relationships and sink regulations of photosynthesis. Carbon 198-204 Glucose-1-phosphate adenylyltransferase family protein Arabidopsis thaliana 185-189 21411937-1 2011 To improve the efficiency of low-strength domestic wastewater treatment, an immobilised-microorganism biological aerated filter (I-BAF) was established for simultaneous carbon, nitrogen and phosphorus removal. Carbon 169-175 BAF nuclear assembly factor 1 Homo sapiens 131-134 21738611-3 2011 How one-carbon nutrients affect the CpG island methylator phenotype (CIMP) or BRAF mutation status in colon cancer remains uncertain. Carbon 8-14 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens 78-82 21289492-3 2011 In yeast, nitrogen and/or carbon limitation causes downregulation of the conserved TORC1 and PKA signaling pathways and consequently activation of Rim15, a member of the PAS protein kinase family. Carbon 26-32 protein kinase RIM15 Saccharomyces cerevisiae S288C 147-152 20932985-0 2011 Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-alpha via distinct NF-kappaB pathways in human nasal epithelial cells. Carbon 7-8 C-X-C motif chemokine ligand 8 Homo sapiens 63-67 20932985-0 2011 Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-alpha via distinct NF-kappaB pathways in human nasal epithelial cells. Carbon 7-8 tumor necrosis factor Homo sapiens 72-81 20932985-6 2011 Both the reduction of JAM-A expression and the induction of secretion of IL-8 and TNF-alpha after treatment with poly(I:C) were modulated by distinct signal transduction pathways via EGFR, PI3K, and p38 MAPK and finally regulated by a TLR3-mediated NF-kappaB pathway. Carbon 120-121 C-X-C motif chemokine ligand 8 Homo sapiens 73-77 20932985-6 2011 Both the reduction of JAM-A expression and the induction of secretion of IL-8 and TNF-alpha after treatment with poly(I:C) were modulated by distinct signal transduction pathways via EGFR, PI3K, and p38 MAPK and finally regulated by a TLR3-mediated NF-kappaB pathway. Carbon 120-121 tumor necrosis factor Homo sapiens 82-91 20932985-6 2011 Both the reduction of JAM-A expression and the induction of secretion of IL-8 and TNF-alpha after treatment with poly(I:C) were modulated by distinct signal transduction pathways via EGFR, PI3K, and p38 MAPK and finally regulated by a TLR3-mediated NF-kappaB pathway. Carbon 120-121 epidermal growth factor receptor Homo sapiens 183-187 21548286-4 2011 In 1985, 1994, 2003, 2020, and 2030, the forest carbon storage was 1.06, 2.83, 4.14, 5.65, and 6.35 Tg C, respectively. Carbon 48-54 transglutaminase 2 Homo sapiens 100-104 21411937-5 2011 The I-BAF system showed excellent performance in carbon and nutrients removal, which provided a cost-effective solution for the treatment of low-strength domestic wastewater. Carbon 49-55 BAF nuclear assembly factor 1 Homo sapiens 6-9 21411941-0 2011 Removal of Pb(II) and Cu(II) from aqueous solution using multiwalled carbon nanotubes/iron oxide magnetic composites. Carbon 69-75 submaxillary gland androgen regulated protein 3B Homo sapiens 11-28 20678463-0 2010 Amperometric immunosensor based on multiwalled carbon nanotubes/Prussian blue/nanogold-modified electrode for determination of alpha-fetoprotein. Carbon 47-53 alpha fetoprotein Homo sapiens 127-144 20961854-5 2010 Using (13)C-detected NMR experiments, we have mapped the residues within the intrinsically unstructured fragment of MLL that are required for binding to menin. Carbon 10-11 menin 1 Homo sapiens 153-158 21170321-7 2010 It is speculated that a mechanism for potential TCA cycle inefficiency concurrent with insulin resistance is "anaplerotic stress" emanating from reduced amino acid-derived carbon flux to TCA cycle intermediates, which if coupled to perturbation in cataplerosis would lead to net reduction in TCA cycle capacity relative to fuel delivery. Carbon 172-178 insulin Homo sapiens 87-94 20678463-1 2010 In this article, a conspicuously simple and highly sensitive amperometric immunosensor based on the sequential electrodeposition of Prussian blue (PB) and gold nanoparticles (GNPs) on multiwalled carbon nanotube (MWCNT)-modified glassy carbon electrode (GCE) surface is proposed for the detection of alpha-fetoprotein (AFP). Carbon 196-202 alpha fetoprotein Homo sapiens 300-317 20678463-1 2010 In this article, a conspicuously simple and highly sensitive amperometric immunosensor based on the sequential electrodeposition of Prussian blue (PB) and gold nanoparticles (GNPs) on multiwalled carbon nanotube (MWCNT)-modified glassy carbon electrode (GCE) surface is proposed for the detection of alpha-fetoprotein (AFP). Carbon 196-202 alpha fetoprotein Homo sapiens 319-322 20964299-5 2010 Carbon nanotube conjugates with adsorbed lysozyme interacted with the liposome through electrostatic interaction, leading to liposome leakage. Carbon 0-6 lysozyme Homo sapiens 41-49 20701625-6 2010 Compared with participants with only one component of the metabolic syndrome, those who had five had an increased TC/HDL-C ratio (73 0% and 80 4% in men and women respectively), apoB/apoA-I ratio (58 0% and 62 9% in men and women respectively) and for LDL(NMR)/HDL(NMR) ratio (52 6% and 54 1% in men and women respectively). Carbon 0-1 apolipoprotein B Homo sapiens 178-182 20701625-6 2010 Compared with participants with only one component of the metabolic syndrome, those who had five had an increased TC/HDL-C ratio (73 0% and 80 4% in men and women respectively), apoB/apoA-I ratio (58 0% and 62 9% in men and women respectively) and for LDL(NMR)/HDL(NMR) ratio (52 6% and 54 1% in men and women respectively). Carbon 0-1 apolipoprotein A1 Homo sapiens 183-189 20932671-8 2010 The expression of S100A8 in lung tissue, a marker of the lung pre-metastatic phase, was decreased only in the group with a combination of carbon ions and DCs. Carbon 138-144 S100 calcium binding protein A8 (calgranulin A) Mus musculus 18-24 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 275-281 androgen receptor Homo sapiens 62-79 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 275-281 androgen receptor Homo sapiens 81-83 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 282-288 androgen receptor Homo sapiens 62-79 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 282-288 androgen receptor Homo sapiens 81-83 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 282-288 androgen receptor Homo sapiens 62-79 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 282-288 androgen receptor Homo sapiens 81-83 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 282-288 androgen receptor Homo sapiens 62-79 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 282-288 androgen receptor Homo sapiens 81-83 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 282-288 androgen receptor Homo sapiens 62-79 21030877-2 2010 However, evidence supports the concept that signaling via the androgen receptor (AR) is important in progression to castration-resistant prostate cancer (CRPC).Steroid hormones are synthesized from cholesterol in a series of tightly regulated steps involving the cleavage of carbon-carbon bonds, the introduction of functional groups derived from activated molecular oxygen, and the oxidation and reduction of carbon-carbon and carbon-oxygen bonds. Carbon 282-288 androgen receptor Homo sapiens 81-83 20876298-0 2010 Ime1 and Ime2 are required for pseudohyphal growth of Saccharomyces cerevisiae on nonfermentable carbon sources. Carbon 97-103 protein kinase IME2 Saccharomyces cerevisiae S288C 9-13 20876298-5 2010 Two stimulators of meiosis, Ime1 and Ime2, are required for pseudohyphal growth of SK1 cells in the presence of nonfermentable carbon sources. Carbon 127-133 protein kinase IME2 Saccharomyces cerevisiae S288C 37-41 20685216-5 2010 Hydroxylations at C-6, C-10, C-11, C-15 positions and alpha,beta-unsaturation at C-1/C-2, C-4/C-5 showed potent inhibitory activities against these enzymes. Carbon 18-19 homeobox C10 Homo sapiens 23-27 21139399-5 2010 4) Synthesis of a two-carbon-elongated homologue (Imz-C(2)-PA) with a combination of POM and 2-cyanoethyl groups. Carbon 22-28 regulator of G protein signaling 3 Homo sapiens 54-61 20971108-0 2010 Activation of the NLRP3 inflammasome by intracellular poly I:C. Carbon 61-62 NLR family pyrin domain containing 3 Homo sapiens 18-23 20945910-0 2010 Adsorption kinetics of catalase to thin films of carbon nanotubes. Carbon 49-55 catalase Homo sapiens 23-31 21051821-3 2010 (2SR,4RS)-7-Methyl-2-exo-(1-naphthyl)-2,3,4,5-tetrahydro-1H-1,4-epoxy-1-benzazepine, C(21)H(19)NO, (II), crystallizes as a true racemate in the space group P2(1)/c, and a combination of C-H...N, C-H...O and C-H...pi(arene) hydrogen bonds links the molecules into sheets, each containing equal numbers of the two enantiomorphs. Carbon 85-86 cyclin dependent kinase inhibitor 1A Homo sapiens 156-163 20933416-2 2010 Analogs with sterically hindering isopropyl and phenyl substituents on the benzylic carbon connecting the aromatic core of W1400 to the acetamidine nitrogen, showed good inhibitory potency for nNOS (IC(50)=0.2 and 0.3 muM) and selectivity over eNOS (500 and 1166) and to a lesser extent over iNOS (50 and 100). Carbon 84-90 latexin Homo sapiens 218-221 20919734-0 2010 Metal impurities dominate the sorption of a commercially available carbon nanotube for Pb(II) from water. Carbon 67-73 submaxillary gland androgen regulated protein 3B Homo sapiens 87-93 20648002-10 2010 Coculture of A. muciniphila with MUC2 as the sole carbon source led to reduction in its abundance while it augmented growth of other bacteria. Carbon 50-56 mucin 2, oligomeric mucus/gel-forming Homo sapiens 33-37 20923141-5 2010 In NO(x) + O(2), NO(2) directly interacts with the free carbon sites (C C*) through two parallel reactions: (1) NO(2) + C C* C C O + NO; (2) NO(2) + C C* NCO(-) + CO(2). Carbon 56-62 ryanodine receptor 1 Homo sapiens 127-132 20674329-1 2010 A novel highly sensitive biosensor for the direct and simultaneous determination of superoxide anion radical (O2-) and nitrite (NO2-) was developed by incorporation of carbon nanotube (CNT) solubilized in nafion in polypyrrole (PPy) matrix on Pt electrode followed by immobilization of Cu,ZnSOD (SOD1) on it. Carbon 168-174 superoxide dismutase 1 Homo sapiens 296-300 20870466-1 2010 An oral sorbent AST-120 composed of spherical porous carbon particles has superior adsorption ability for certain small-molecular-weight organic compounds known to accumulate in patients with chronic renal failure (CRF). Carbon 53-59 solute carrier family 17 member 5 Homo sapiens 16-19 20836715-7 2010 These results demonstrate that poly I:C-stimulated M-SMCs phosphorylate Akt, produce HA cables, and promote HA-mediated leukocyte adhesion through a PI3K/Akt-dependent manner. Carbon 38-39 AKT serine/threonine kinase 1 Homo sapiens 72-75 20836715-7 2010 These results demonstrate that poly I:C-stimulated M-SMCs phosphorylate Akt, produce HA cables, and promote HA-mediated leukocyte adhesion through a PI3K/Akt-dependent manner. Carbon 38-39 AKT serine/threonine kinase 1 Homo sapiens 154-157 20937899-5 2010 We find a moderate sink of 0.5 +- 0.4 PgC y(-1) for the period 2004-2006 for the coterminous United States, in good agreement with the forest-inventory-based estimate of the first North American State of the Carbon Cycle Report, and averaged climate conditions. Carbon 208-214 progastricsin Homo sapiens 38-41 20868224-0 2010 c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy. Carbon 73-79 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 0-5 20868224-0 2010 c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy. Carbon 73-79 mitogen-activated protein kinase 3 Homo sapiens 29-35 20555363-2 2010 To investigate the role of methylotrophy in the cycling of carbon in this unusual environment, stable-isotope probing (SIP) was carried out using the one-carbon compounds methane, methanol and methylamine. Carbon 154-160 tumor protein p53 inducible nuclear protein 1 Homo sapiens 95-123 20686417-4 2010 Niacin is a unique lipid-lowering medication with a capacity to lower low-density lipoprotein cholesterol (LDL-c), triglyceride and increase HDL-c. Carbon 3-4 component of oligomeric golgi complex 2 Homo sapiens 107-112 20938491-4 2010 This work also showed SOD rates to be positively correlated with the concentration of total organic carbon. Carbon 100-106 superoxide dismutase 1 Homo sapiens 22-25 21137401-0 2010 [Fluorescence study on the interactions between carbon nanotubes and bovine serum albumin]. Carbon 48-54 albumin Homo sapiens 76-90 21049883-7 2010 The variation in the estimated net removal of NO3- from developed watersheds was related to both drainage area and the availability of organic carbon. Carbon 143-149 NBL1, DAN family BMP antagonist Homo sapiens 46-49 20799898-1 2010 BACKGROUND: Taq1B polymorphism of cholesteryl ester transfer protein (CETP) is believed to associate with high-density lipoprotein-cholesterol (HDL-C) levels and may alter the susceptibility to atherosclerosis. Carbon 147-149 cholesteryl ester transfer protein Homo sapiens 34-68 20799898-1 2010 BACKGROUND: Taq1B polymorphism of cholesteryl ester transfer protein (CETP) is believed to associate with high-density lipoprotein-cholesterol (HDL-C) levels and may alter the susceptibility to atherosclerosis. Carbon 147-149 cholesteryl ester transfer protein Homo sapiens 70-74 20801357-1 2010 A simple and sensitive sandwich-type electrochemiluminescence immunosensor for alpha-1-fetoprotein (AFP) on a gold nanoparticles (nano-Au) modified glassy carbon electrode (GCE) was developed by using Ru-silica (Ru(bpy)(3)(2+)-doped silica) doped Au (Ru-silica@Au) composite as labels. Carbon 155-161 alpha fetoprotein Homo sapiens 79-98 20659277-1 2010 The glucose-6-phosphate/phosphate antiporter GPT1 is a major route of entry of carbon into non-photosynthetic plastids. Carbon 79-85 glucose 6-phosphate/phosphate translocator 1 Arabidopsis thaliana 45-49 20659274-2 2010 Disruption of the TREHALOSE 6-PHOSPHATE SYNTHASE (TPS1) gene in Arabidopsis results in delayed embryo growth, altered cell wall morphology and carbon metabolism and abortion at the torpedo stage. Carbon 143-149 trehalose-6-phosphate synthase Arabidopsis thaliana 18-48 20659274-2 2010 Disruption of the TREHALOSE 6-PHOSPHATE SYNTHASE (TPS1) gene in Arabidopsis results in delayed embryo growth, altered cell wall morphology and carbon metabolism and abortion at the torpedo stage. Carbon 143-149 trehalose-6-phosphate synthase Arabidopsis thaliana 50-54 20638968-7 2010 The Sips isotherm predicted the equilibrium data well and the maximum Pb(II) uptake capacity of C-NMOC (4.64% Mn loading) was estimated to be 80.1 mg g(-1). Carbon 96-97 submaxillary gland androgen regulated protein 3B Homo sapiens 70-76 20801357-1 2010 A simple and sensitive sandwich-type electrochemiluminescence immunosensor for alpha-1-fetoprotein (AFP) on a gold nanoparticles (nano-Au) modified glassy carbon electrode (GCE) was developed by using Ru-silica (Ru(bpy)(3)(2+)-doped silica) doped Au (Ru-silica@Au) composite as labels. Carbon 155-161 alpha fetoprotein Homo sapiens 100-103 19760087-5 2010 The most abundant species on the backup quartz filters were OC2 (250 degrees C) and OC3 (450 degrees C), accounting for approximately 80% of measured organic carbon on the backup quartz filters. Carbon 158-164 one cut homeobox 3 Homo sapiens 84-87 20624405-7 2010 SIGNIFICANCE: our study demonstrates that the short-carbon chain C(2)-ceramide can effectively sensitize PTX-induced senescence of H1299 cells via both p21(waf1/cip1)- and p16(ink4)-independent pathways. Carbon 52-58 cyclin dependent kinase inhibitor 1A Homo sapiens 152-165 20624405-7 2010 SIGNIFICANCE: our study demonstrates that the short-carbon chain C(2)-ceramide can effectively sensitize PTX-induced senescence of H1299 cells via both p21(waf1/cip1)- and p16(ink4)-independent pathways. Carbon 52-58 cyclin dependent kinase inhibitor 2A Homo sapiens 172-175 20624405-7 2010 SIGNIFICANCE: our study demonstrates that the short-carbon chain C(2)-ceramide can effectively sensitize PTX-induced senescence of H1299 cells via both p21(waf1/cip1)- and p16(ink4)-independent pathways. Carbon 52-58 cyclin dependent kinase inhibitor 2A Homo sapiens 176-180 20687575-0 2010 Bovine serum albumin-catalyzed deprotonation of [1-(13)C]glycolaldehyde: protein reactivity toward deprotonation of the alpha-hydroxy alpha-carbonyl carbon. Carbon 140-146 albumin Homo sapiens 7-20 20814093-3 2010 The methyl group also acts as a weak hydrogen-bond donor, symmetry-related to the latter described C-H...O=C interaction, to a third molecule at (x, -y - 1/2, z + 1/2) to form a two-dimensional network. Carbon 99-100 RNA, Ro60-associated Y1 Homo sapiens 149-166 20627666-0 2010 A sensitive amperometric immunosensor for alpha-fetoprotein based on carbon nanotube/DNA/Thi/nano-Au modified glassy carbon electrode. Carbon 69-75 alpha fetoprotein Homo sapiens 42-59 20627666-0 2010 A sensitive amperometric immunosensor for alpha-fetoprotein based on carbon nanotube/DNA/Thi/nano-Au modified glassy carbon electrode. Carbon 117-123 alpha fetoprotein Homo sapiens 42-59 20627666-1 2010 A novel amperometric immunosensor for the determination of alpha-fetoprotein (AFP) was constructed using films of multi-wall carbon nanotubes/DNA/thionine/gold nanoparticles (nano-Au). Carbon 125-131 alpha fetoprotein Homo sapiens 59-76 20627666-1 2010 A novel amperometric immunosensor for the determination of alpha-fetoprotein (AFP) was constructed using films of multi-wall carbon nanotubes/DNA/thionine/gold nanoparticles (nano-Au). Carbon 125-131 alpha fetoprotein Homo sapiens 78-81 21587373-1 2010 In the title compound, [CrCl(3)(C(19)H(13)Br(2)N(3))], the Cr(3+ )ion is coordinated by the tridentate 2,6-bis-[(4-bromo-phen-yl)imino-meth-yl]pyridine Schiff base ligand in a fac-octa-hedral geometry. Carbon 24-25 FA complementation group C Homo sapiens 176-179 21587377-1 2010 In the polymeric title compound, [Co(2)(C(3)H(7)NO)(3)(C(8)H(3)NO(6))(2)] C(3)H(7)NO, one 5-nitro-isophthalate dianion has its two carboxyl-ate groups chelating to one Co(II) atom while simultaneously coordinating to another metal atom in a mu(4)-bridging mode. Carbon 34-35 mitochondrially encoded cytochrome c oxidase II Homo sapiens 168-174 20219156-6 2010 We found that adult offspring born to PolyI:C-treated mothers showed delay-dependent impairments in spatial working memory and recognition memory together with a marked reduction of AKT1-positive cells in the prefrontal cortex. Carbon 44-45 thymoma viral proto-oncogene 1 Mus musculus 182-186 20691338-5 2010 The structure-activity data acquired indicate that the geometry of propenone and also the type of substituents on the C-3 propenone are important for COX-2 inhibitory activity. Carbon 118-119 mitochondrially encoded cytochrome c oxidase II Homo sapiens 150-155 20690969-2 2010 However, the very provision of healthcare itself has a significant environmental impact, and the contribution of kidney care to the carbon footprint of the NHS is likely to be disproportionately high. Carbon 132-138 NHS actin remodeling regulator Homo sapiens 156-159 20526655-6 2010 ATR spectrum of microspheres showed peaks for aromatic C=C stretching and substituted benzene ring, indicating entrapment of flurbiprofen. Carbon 55-56 ATR serine/threonine kinase Homo sapiens 0-3 20526655-6 2010 ATR spectrum of microspheres showed peaks for aromatic C=C stretching and substituted benzene ring, indicating entrapment of flurbiprofen. Carbon 57-58 ATR serine/threonine kinase Homo sapiens 0-3 21133088-0 2010 Detection of organophosphate pesticide using polyaniline and carbon nanotubes composite based on acetylcholinesterase inhibition. Carbon 61-67 acetylcholinesterase (Cartwright blood group) Homo sapiens 97-117 20446743-8 2010 For the case where both the donor and acceptor occupy equatorial positions on a rigid cyclohexane bridge, we find beta(calc) = 2.8 per C-C bond, compared with the experimental value beta(exp) = 2.6. Carbon 135-136 calcitonin related polypeptide beta Homo sapiens 114-128 20712627-9 2010 The possible function of GPT2 in starch-free mutants is discussed in the background of carbon requirement in leaves during the light-dark cycle. Carbon 87-93 glucose-6-phosphate/phosphate translocator 2 Arabidopsis thaliana 25-29 21265144-4 2010 155 Tg, and the biomass carbon loss was about 30.993 Tg C, accounting for 15.92% of the vegetation carbon pool in the whole province. Carbon 24-30 transglutaminase 2 Homo sapiens 53-57 20446743-8 2010 For the case where both the donor and acceptor occupy equatorial positions on a rigid cyclohexane bridge, we find beta(calc) = 2.8 per C-C bond, compared with the experimental value beta(exp) = 2.6. Carbon 137-138 calcitonin related polypeptide beta Homo sapiens 114-128 20690752-5 2010 The formation of L5(Me2) requires (i) the admission of air, (ii) the presence of both methoxy substituents of L3(Me2), and (iii) the presence of (methyl) substituents both at the exocyclic carbon atom and at the 5- positions of the pyrazolyl rings. Carbon 189-195 malic enzyme 2 Homo sapiens 20-23 20666372-6 2010 The peapod-like nanostructure of Co(3)O(4)@carbon demonstrates very high specific capacity (around 1000 mAh/g at the charge/discharge rate of 1C) and wonderful cyclability (at least 80% retention is available when cycled back from very high charge/discharge rate of 10C) during the galvanostatic cycling, indicating it as the promising candidate for Li-ion batteries" anodes. Carbon 43-49 Rho GTPase activating protein 9 Homo sapiens 266-269 20608685-3 2010 We demonstrate a method for detecting and quantifying point defect density in individual carbon nanotubes (CNTs) based on measuring the polarization dependence (linear dichroism) of the C 1s --> pi* transition at specific locations along individual CNTs with a scanning transmission X-ray microscope (STXM). Carbon 89-95 complement C1s Homo sapiens 186-190 21588541-1 2010 In the title mononuclear cobalt(III) compound, [Co(C(9)H(8)ClNO(2))(C(9)H(9)ClNO(2))], the Co(II) atom is six-coordinated by two imine N atoms, two phenolate O atoms, and one hy-droxy and one oxide O atom from two Schiff base ligands, forming an octa-hedral geometry. Carbon 48-49 mitochondrially encoded cytochrome c oxidase II Homo sapiens 91-97 20690752-5 2010 The formation of L5(Me2) requires (i) the admission of air, (ii) the presence of both methoxy substituents of L3(Me2), and (iii) the presence of (methyl) substituents both at the exocyclic carbon atom and at the 5- positions of the pyrazolyl rings. Carbon 189-195 malic enzyme 2 Homo sapiens 113-116 20608681-1 2010 Five carbazole end-capped heterofluorenes (CzHFs) designed by structurally mimicking 4,4"-N,N"-dicarbazole-biphenyl (CBP) via connecting the biphenyl core of CBP with the linking atom of C, P, N, O, and S, respectively, were synthesized successfully, and their optoelectronic properties were investigated. Carbon 43-44 CREB binding protein Homo sapiens 117-120 21253464-7 2010 Other phenotypes identified suggest that AIM45, YGR207c/CIR1 and YOR356w/CIR2 can protect cells from oxidative and heat stress, which encompass increased heat stress sensitivity, superoxide sensitivity, both only on non-fermentable carbon sources. Carbon 232-238 Cir1p Saccharomyces cerevisiae S288C 56-60 20570722-1 2010 Cell-membrane-dependent proliferative signal transduction activated by ultrafine carbon particles in lung epithelial cells involves the specific induction of Akt and ERK1/2 phosphorylation. Carbon 81-87 AKT serine/threonine kinase 1 Homo sapiens 158-161 20570722-1 2010 Cell-membrane-dependent proliferative signal transduction activated by ultrafine carbon particles in lung epithelial cells involves the specific induction of Akt and ERK1/2 phosphorylation. Carbon 81-87 mitogen-activated protein kinase 3 Homo sapiens 166-172 20466535-1 2010 In this study, a novel acetylcholinesterase (AChE) biosensor was developed based on dual-layer membranes (chitosan membrane and prussian blue membrane) modifying glassy carbon electrode (GCE). Carbon 169-175 acetylcholinesterase (Cartwright blood group) Homo sapiens 23-43 20466535-1 2010 In this study, a novel acetylcholinesterase (AChE) biosensor was developed based on dual-layer membranes (chitosan membrane and prussian blue membrane) modifying glassy carbon electrode (GCE). Carbon 169-175 acetylcholinesterase (Cartwright blood group) Homo sapiens 45-49 20483583-0 2010 Conductive carbon nanoparticles-based electrochemical immunosensor with enhanced sensitivity for alpha-fetoprotein using irregular-shaped gold nanoparticles-labeled enzyme-linked antibodies as signal improvement. Carbon 11-17 alpha fetoprotein Homo sapiens 97-114 20483583-1 2010 A new electrochemical immunoassay protocol for sensitive detection of alpha-fetoprotein (AFP, as a model) is designed using carbon nanoparticles (CNPs)-functionalized biomimetic interface as immunosensing probe and irregular-shaped gold nanoparticles (ISNGs)-labeled horseradish peroxidase-anti-AFP conjugates (HRP-anti-AFP-ISNG) as trace label. Carbon 124-130 alpha fetoprotein Homo sapiens 70-87 20483583-1 2010 A new electrochemical immunoassay protocol for sensitive detection of alpha-fetoprotein (AFP, as a model) is designed using carbon nanoparticles (CNPs)-functionalized biomimetic interface as immunosensing probe and irregular-shaped gold nanoparticles (ISNGs)-labeled horseradish peroxidase-anti-AFP conjugates (HRP-anti-AFP-ISNG) as trace label. Carbon 124-130 alpha fetoprotein Homo sapiens 89-92 19902353-9 2010 In conclusion, elevated C-41/42 is likely the result of elevated AAT synthesis, and the activity of specific MMPs present within the tumor. Carbon 24-25 serpin family A member 1 Homo sapiens 65-68 20489167-9 2010 CONCLUSIONS: This study provides evidence of the following: (1) in mice, loss of NPC1 function reduces hepatocyte TG content and secretion by increasing the metabolic flux of carbons into cholesterol synthesis; and (2) common variation in NPC1 contributes to serum TG levels in humans. Carbon 175-182 NPC intracellular cholesterol transporter 1 Mus musculus 81-85 19902353-8 2010 The full length AAT showed a consistent expression pattern as C-41/42, and C-41/42 can be generated in vitro by MMP-7 cleavage. Carbon 62-63 serpin family A member 1 Homo sapiens 16-19 19902353-8 2010 The full length AAT showed a consistent expression pattern as C-41/42, and C-41/42 can be generated in vitro by MMP-7 cleavage. Carbon 75-76 serpin family A member 1 Homo sapiens 16-19 20617795-0 2010 Cavity ring down and Fourier transform infrared spectroscopy at low temperatures (84-297 K): Fermi resonance and intensities of the C-H fundamental and overtone (Delta(upsilon) = 1-6) transitions of CHD(3). Carbon 0-1 chromodomain helicase DNA binding protein 3 Homo sapiens 199-205 19902353-10 2010 As other C-terminal fragments of AAT are reported to function as tumor-derived suppressors to the host immune-system, elevated C-41/42 may also be predictive of a poor outcome. Carbon 9-10 serpin family A member 1 Homo sapiens 33-36 20491943-5 2010 Trm2p was localized to the nucleus during growth on nonfermentable carbon sources, but to the cytosol during growth on glucose. Carbon 67-73 tRNA (uracil(54)-C(5))-methyltransferase Saccharomyces cerevisiae S288C 0-5 20589880-8 2010 CONCLUSIONS: Curly tail fibroblasts and embryos, in which Grhl3 expression is reduced, display alterations in one-carbon metabolism, particularly in the response to folate deficiency, compared to genetically matched congenic controls in which Grhl3 is unaffected. Carbon 114-120 grainyhead like transcription factor 3 Mus musculus 58-63 20821618-4 2010 Relative binding affinities of L-FABP with PFCAs of carbon chain lengths of five to nine were established fluorimetrically. Carbon 52-58 fatty acid binding protein 1 Rattus norvegicus 31-37 20458405-0 2010 Multiwalled carbon nanotube modified with 1-(2-pyridylazo)-2-naphthol for stripping voltammetric determination of Pb(II). Carbon 12-18 submaxillary gland androgen regulated protein 3B Homo sapiens 114-120 20452761-2 2010 The target protein thrombin is sandwiched between an electrode surface confined aptamer and an aptamer-enzyme-carbon nanotube bioconjugate. Carbon 110-116 coagulation factor II, thrombin Homo sapiens 19-27 20388583-0 2010 Effect of reaction environments on the reactivity of PCB (2-chlorobiphenyl) over activated carbon impregnated with palladized iron. Carbon 91-97 pyruvate carboxylase Homo sapiens 53-56 20559653-0 2010 Arabidopsis sucrose synthase 2 and 3 modulate metabolic homeostasis and direct carbon towards starch synthesis in developing seeds. Carbon 79-85 sucrose synthase 2 Arabidopsis thaliana 12-28 20559653-7 2010 It seems that sucrolysis via SUS is not required for oil or protein synthesis but rather for channeling carbon toward ADP-glucose and starch in seeds. Carbon 104-110 sucrose synthase 2 Arabidopsis thaliana 29-32 21588110-1 2010 In the title complex, [Co(C(22)H(15)O(5))(2)(C(2)H(5)OH)(2)], the Co(II) atom (site symmetry ) is coordinated by two O,O"-bidentate 4-(2-benzoyl-1-oxidoethen-yl)-3-hy-droxy-phenyl benzoate anions and two ethanol O atoms, resulting in a slightly distorted CoO(6) octa-hedral coordination. Carbon 23-24 mitochondrially encoded cytochrome c oxidase II Homo sapiens 66-72 20533850-4 2010 LiBH4 and MgH2 nanoparticles are embedded in a nanoporous carbon aerogel scaffold with pore size Dmax approximately 21 nm and react during release of hydrogen and form MgB2. Carbon 58-64 secretoglobin family 2A member 1 Homo sapiens 168-172 20472422-0 2010 Acetylcholinesterase biosensor design based on carbon nanotube-encapsulated polypyrrole and polyaniline copolymer for amperometric detection of organophosphates. Carbon 47-53 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 20472422-1 2010 A simple method to immobilize acetylcholinesterase (AChE) on polypyrrole (PPy) and polyaniline (PANI) copolymer doped with multi-walled carbon nanotubes (MWCNTs) was proposed. Carbon 136-142 acetylcholinesterase (Cartwright blood group) Homo sapiens 30-50 20472422-1 2010 A simple method to immobilize acetylcholinesterase (AChE) on polypyrrole (PPy) and polyaniline (PANI) copolymer doped with multi-walled carbon nanotubes (MWCNTs) was proposed. Carbon 136-142 acetylcholinesterase (Cartwright blood group) Homo sapiens 52-56 20458405-1 2010 The present work is focused on the modification of multiwalled carbon nanotubes with a ligand, 1-(2-pyridylazo)-2-naphthol (PAN), and its potential application for the development of a new, simple and selective modified glassy carbon electrode for stripping voltammetric determination of Pb(II). Carbon 63-69 submaxillary gland androgen regulated protein 3B Homo sapiens 288-294 21122658-8 2010 Clinical concordance between D-LDL-C and C-LDL-C was present in 40% of patients, whereas clinical discordance was noted in 25%. Carbon 0-1 component of oligomeric golgi complex 2 Homo sapiens 31-36 20552645-5 2010 In this mechanism, the rate constant of the reaction would be directly related with the strength of the nucleophilic attack of the C-1 hydroxyl group, which depends on the chemical shift of the carbon C-1 (delta(1)) obtained by (13)C-NMR. Carbon 131-132 delta like non-canonical Notch ligand 1 Homo sapiens 201-214 21122658-8 2010 Clinical concordance between D-LDL-C and C-LDL-C was present in 40% of patients, whereas clinical discordance was noted in 25%. Carbon 0-1 component of oligomeric golgi complex 2 Homo sapiens 43-48 20448103-7 2010 Other mechanisms related to N and carbon nutrition regulating NRT2.1 or involved in the control of root SO(4)(-) uptake by the plant sulfur status are not or are slightly affected. Carbon 34-40 nitrate transporter 2:1 Arabidopsis thaliana 62-66 20376694-0 2010 A new phosphorimetry for the determination of trace alkaline phosphatase using multi-wall carbon nanotubes and its diagnosis of human diseases. Carbon 90-96 alkaline phosphatase, placental Homo sapiens 52-72 20618705-5 2010 Deletion of atg8 abolished autophagosome accumulation in the vacuoles of carbon-starved cells and drastically reduced the survival of U. maydisDeltaatg8 mutant strains during these conditions. Carbon 73-79 ubiquitin-like protein ATG8 Saccharomyces cerevisiae S288C 12-16 20395293-7 2010 c/CL takes place via an overall scheme comparable to that described for cytochrome c" and guanylate cyclase, the final product being one in which NO resides on the proximal side of the heme. Carbon 0-1 cytochrome c, somatic Homo sapiens 72-84 20685471-1 2010 A new gallium (Ga(III)) ion-imprinted multi-walled carbon nanotubes (CNTs) composite sorbent was synthesized by a surface imprinting technique. Carbon 51-57 l(2)46Cc Drosophila melanogaster 15-22 20685471-2 2010 The Ga(III) ion-imprinted/multi-walled carbon nanotubes (Ga(III)-imprinted/CNTs) sorbent was characterized by Fourier transform infrared (FT-IR), X-ray diffraction (XRD), nitrogen adsorption experiment, static adsorption experiment, and solid-phase extraction (SPE) experiment. Carbon 39-45 l(2)46Cc Drosophila melanogaster 4-11 20685471-2 2010 The Ga(III) ion-imprinted/multi-walled carbon nanotubes (Ga(III)-imprinted/CNTs) sorbent was characterized by Fourier transform infrared (FT-IR), X-ray diffraction (XRD), nitrogen adsorption experiment, static adsorption experiment, and solid-phase extraction (SPE) experiment. Carbon 39-45 l(2)46Cc Drosophila melanogaster 57-64 20441948-0 2010 Carbon nanotube-enhanced electrochemical aptasensor for the detection of thrombin. Carbon 0-6 coagulation factor II, thrombin Homo sapiens 73-81 20465238-1 2010 4-Oxalocrotonate tautomerase (4-OT) isozymes play prominent roles in the bacterial utilization of aromatic hydrocarbons as sole carbon sources. Carbon 112-118 Caur_1354 Chloroflexus aurantiacus J-10-fl 0-28 20572695-3 2010 Employing the recently proposed perspective of delocalization error within DFT we rationalize this failure of common density functional approximations (DFAs) and present calculations with the rCAM-B3LYP exchange-correlation functional that show an angle-to-bond-alternation transition between C(10) and C(14). Carbon 193-194 homeobox C10 Homo sapiens 293-298 20441948-1 2010 A novel electrochemical aptasensor for the detection of thrombin was developed on basis of the thrombin-binding aptamer (TBA) as a molecular recognition element and multi-walled carbon nanotubes (MWCNTs) as a carrier of the electrochemical capture probe. Carbon 178-184 coagulation factor II, thrombin Homo sapiens 56-64 20651340-6 2010 The RBE of carbon beam was larger in mutant-type p53 cells than in wild-type p53 cells. Carbon 11-17 tumor protein p53 Homo sapiens 49-52 20730122-3 2010 The minimum turn-on and threshold fields were 0.68 and 1.09 V/mum, respectively, which were lower than those of the as-grown carbon nanotubes. Carbon 125-131 latexin Homo sapiens 8-11 20651340-6 2010 The RBE of carbon beam was larger in mutant-type p53 cells than in wild-type p53 cells. Carbon 11-17 tumor protein p53 Homo sapiens 77-80 20403834-6 2010 The plausible range of carbon mass input, approximately 4000-7000 PgC, strongly suggests a major alternative source of carbon in addition to any contribution from methane hydrates. Carbon 119-125 progastricsin Homo sapiens 66-69 20404857-1 2010 1-Deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) is an important enzyme involved in the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway which provides the basic five-carbon units for isoprenoid biosynthesis. Carbon 173-179 1-deoxy-D-xylulose 5-phosphate reductoisomerase Arabidopsis thaliana 0-47 20404857-1 2010 1-Deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) is an important enzyme involved in the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway which provides the basic five-carbon units for isoprenoid biosynthesis. Carbon 173-179 1-deoxy-D-xylulose 5-phosphate reductoisomerase Arabidopsis thaliana 49-52 20606811-6 2010 The formation of carbon-centered (1-hydroxyethyl) and oxygen-centered (hydroxyl) radicals during the metabolism of ethanol is considered: the generation of hydroxyethyl radicals, which occurs likely during the process of univalent reduction of dioxygen, is highlighted and is carried out by ferric cytochrome P(450) oxy-complex (P(450)-Fe(3+)O(2) (.-)) formed during the reduction of heme-oxygen. Carbon 17-23 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 298-315 21179939-0 2010 Nuclear translocation of Nrf2 and expression of antioxidant defence genes in THP-1 cells exposed to carbon nanotubes. Carbon 100-106 NFE2 like bZIP transcription factor 2 Homo sapiens 25-29 21179939-4 2010 We examine here the effects of multiwalled carbon nanotubes of different sizes on monocytic THP-1 cells, with regard to their ability to stimulate increased expression of the HO-1 and GST genes and their ability to produce nuclear translocation of the transcription factor, Nrf2, as well as the release of several pro-inflammatory cytokines and mediators of inflammation. Carbon 43-49 NFE2 like bZIP transcription factor 2 Homo sapiens 274-278 21179939-5 2010 Our results suggest that long (50 microm) carbon nanotubes (62.5 microg/ml for 4 hours) produce increased nuclear translocation of Nrf2 and increased HO-1 gene expression compared with shorter entangled nanotubes. Carbon 42-48 NFE2 like bZIP transcription factor 2 Homo sapiens 131-135 20561444-4 2010 The results showed that the mean levels of plasma CRP, Fg, FVIII:C and FIX:C were significantly higher in deep vein thrombosis group than that in controls [CRP (2.67 +/- 0.91) vs (0.14 +/- 0.08) mg/dl; Fg (4.73 +/- 1.36) vs (2.79 +/- 0.66)g/L; FVIII:C (126.71 +/- 28.10) vs (81.35 +/- 20.77)%; FIX:C (81.01 +/- 23.60) vs (70.71 +/- 11.3)%] (p < 0.01), and the level of plasma CRP was strongly correlated with Fg, FVIII:C and FIX:C (r(s) = 0.432, 0.571 and 0.544, p < 0.01). Carbon 50-51 C-reactive protein Homo sapiens 156-159 20561444-4 2010 The results showed that the mean levels of plasma CRP, Fg, FVIII:C and FIX:C were significantly higher in deep vein thrombosis group than that in controls [CRP (2.67 +/- 0.91) vs (0.14 +/- 0.08) mg/dl; Fg (4.73 +/- 1.36) vs (2.79 +/- 0.66)g/L; FVIII:C (126.71 +/- 28.10) vs (81.35 +/- 20.77)%; FIX:C (81.01 +/- 23.60) vs (70.71 +/- 11.3)%] (p < 0.01), and the level of plasma CRP was strongly correlated with Fg, FVIII:C and FIX:C (r(s) = 0.432, 0.571 and 0.544, p < 0.01). Carbon 50-51 C-reactive protein Homo sapiens 156-159 20403834-6 2010 The plausible range of carbon mass input, approximately 4000-7000 PgC, strongly suggests a major alternative source of carbon in addition to any contribution from methane hydrates. Carbon 23-29 progastricsin Homo sapiens 66-69 20451395-2 2010 The MAO-B catalyzed 2-electron alpha-carbon oxidation of this class of substrates appears to be dependent on the presence of the allylic pi-bond since the corresponding saturated piperidinyl analogue of MPTP is reported not to be an MAO-B substrate. Carbon 37-43 monoamine oxidase B Mus musculus 4-9 20396930-1 2010 We perform a detailed comparison of fast backbone dynamics probed at amide nitrogen versus carbonyl carbon sites for dematin headpiece C-terminal domain (DHP) and its S74E mutant (DHPS74E). Carbon 91-97 dihydropyrimidinase Homo sapiens 154-157 20467837-3 2010 This lipid mediator is a docosanoid because it is derived from the 22 carbon (22C) precursor DHA, unlike eicosanoids, which are derived from the 20 carbon (20C) arachidonic acid (AA) family member of essential fatty acids. Carbon 148-154 amyloid beta precursor protein Homo sapiens 179-181 20397730-0 2010 Impact of carbon chain length on binding of perfluoroalkyl acids to bovine serum albumin determined by spectroscopic methods. Carbon 10-16 albumin Homo sapiens 75-88 20227086-0 2010 Amperometric immunosensor for the determination of alpha-1-fetoprotein based on multiwalled carbon nanotube-silver nanoparticle composite. Carbon 92-98 alpha fetoprotein Homo sapiens 51-70 20471941-2 2010 In yeast, nitrogen and/or carbon limitation causes downregulation of the conserved TORC1 and PKA signaling pathways and, consequently, activation of the PAS kinase Rim15, which orchestrates G(0) program initiation and ensures proper life span by controlling distal readouts, including the expression of specific genes. Carbon 26-32 protein kinase RIM15 Saccharomyces cerevisiae S288C 164-169 29308103-0 2010 Single-Walled Carbon Nanotubes Probing the Denaturation of Lysozyme. Carbon 14-20 lysozyme Homo sapiens 59-67 29308103-1 2010 Resonance Raman spectroscopy measurements of lysozyme-bound single-walled carbon nanotubes have been made during different stages of the chemically and thermally induced misfolding and of the denaturation process of nanotube-bound lysozymes. Carbon 74-80 lysozyme Homo sapiens 45-53 29308103-2 2010 Changes to the Raman intensity of single-walled carbon nanotubes (SWNTs) have been observed during the denaturation of lysozyme. Carbon 48-54 lysozyme Homo sapiens 119-127 20384431-6 2010 Pearson"s correlation analyses indicated that sputum NEP activity was significantly associated with personal exposure product (elemental carbon concentration [mg/m(3)] x time [min]; C x T). Carbon 137-143 membrane metalloendopeptidase Homo sapiens 53-56 20392087-8 2010 Unlike (210)Pb, atmospheric PCB exchange with the water"s surface is partially forced by the aquatic organic carbon cycle. Carbon 109-115 pyruvate carboxylase Homo sapiens 28-31 20392087-10 2010 If future marine production and vertical flux of carbon increase due to loss of ice cover or change in river input as consequences of global warming, PCB deposition would also increase. Carbon 49-55 pyruvate carboxylase Homo sapiens 150-153 20096366-9 2010 ELOVL4 protein participates in the synthesis of fatty acids with chain length longer than 26 carbons. Carbon 93-100 ELOVL fatty acid elongase 4 Homo sapiens 0-6 20364135-0 2010 Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation. Carbon 0-6 myeloperoxidase Homo sapiens 40-55 20364135-3 2010 Here, we show that hypochlorite and reactive radical intermediates of the human neutrophil enzyme myeloperoxidase catalyse the biodegradation of single-walled carbon nanotubes in vitro, in neutrophils and to a lesser degree in macrophages. Carbon 159-165 myeloperoxidase Homo sapiens 98-113 19884647-9 2010 Larger effects of black carbon on sVCAM were seen in subjects with obesity (p=0.007) and who were GSTM1 null (p=0.02). Carbon 24-30 glutathione S-transferase mu 1 Homo sapiens 98-103 20373820-0 2010 New insights into the behavior of bovine serum albumin adsorbed onto carbon nanotubes: comprehensive spectroscopic studies. Carbon 69-75 albumin Homo sapiens 41-54 20373820-1 2010 Bovine serum albumin (BSA) nonspecifically binds to well-dispersed multiwalled carbon nanotubes (MWCNTs), forming a stable bioconjugate. Carbon 79-85 albumin Homo sapiens 7-20 20192182-0 2010 Ultrasensitive electrochemical immunosensor for oral cancer biomarker IL-6 using carbon nanotube forest electrodes and multilabel amplification. Carbon 81-87 interleukin 6 Homo sapiens 70-74 20192182-5 2010 Secondary antibodies (Ab(2)) attached to carboxylated multiwall carbon nanotubes with 106 HRP labels per 100 nm gave the highest sensitivity of 19.3 nA mL (pg IL-6)(-1) cm(-2) and the best detection limit (DL) of 0.5 pg mL(-1) (25 fM) for IL-6 in 10 microL of calf serum. Carbon 64-70 interleukin 6 Homo sapiens 159-163 20192182-5 2010 Secondary antibodies (Ab(2)) attached to carboxylated multiwall carbon nanotubes with 106 HRP labels per 100 nm gave the highest sensitivity of 19.3 nA mL (pg IL-6)(-1) cm(-2) and the best detection limit (DL) of 0.5 pg mL(-1) (25 fM) for IL-6 in 10 microL of calf serum. Carbon 64-70 interleukin 6 Homo sapiens 239-243 20381697-3 2010 The carcinoembryonic antibody (anti-CEA) was immobilized on the modified magnetic particles, which were then attached on the surface of solid paraffin carbon paste electrode (SPCE) by an external magnetic field. Carbon 151-157 CEA cell adhesion molecule 3 Homo sapiens 36-39 20164309-2 2010 Methylenetetrahydrofolate reductase (MTHFR), choline, and riboflavin play distinct roles in homocysteine detoxification and generation of one-carbon donors for methylation. Carbon 142-148 methylenetetrahydrofolate reductase Mus musculus 0-35 20178368-2 2010 Two dimensional correlation solid state NMR experiments for (1)H-(13)C and (1)H-(31)P nuclei have been used to prove the formation of P-O-C bonds arising from nucleophilic attack of POH mainly to carbon 1 and, to a lesser extent, to carbon 2 of epoxydodecane. Carbon 196-202 proopiomelanocortin Homo sapiens 134-139 20178368-2 2010 Two dimensional correlation solid state NMR experiments for (1)H-(13)C and (1)H-(31)P nuclei have been used to prove the formation of P-O-C bonds arising from nucleophilic attack of POH mainly to carbon 1 and, to a lesser extent, to carbon 2 of epoxydodecane. Carbon 233-239 proopiomelanocortin Homo sapiens 134-139 20164309-2 2010 Methylenetetrahydrofolate reductase (MTHFR), choline, and riboflavin play distinct roles in homocysteine detoxification and generation of one-carbon donors for methylation. Carbon 142-148 methylenetetrahydrofolate reductase Mus musculus 37-42 20376324-0 2010 Genetic analysis of central carbon metabolism unveils an amino acid substitution that alters maize NAD-dependent isocitrate dehydrogenase activity. Carbon 28-34 isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial Zea mays 99-137 20371980-0 2010 Serum level of expressed in renal carcinoma (ERC)/ mesothelin in rats with mesothelial proliferative lesions induced by multi-wall carbon nanotube (MWCNT). Carbon 131-137 mesothelin Rattus norvegicus 51-61 20093293-6 2010 Expression of aceA in PAO1, a P. aeruginosa isolate associated with acute infection, is regulated by carbon sources that utilize the glyoxyate pathway. Carbon 101-107 isocitrate lyase Pseudomonas aeruginosa PAO1 14-18 20208549-0 2010 Detection of single-molecule H2O2 signalling from epidermal growth factor receptor using fluorescent single-walled carbon nanotubes. Carbon 115-121 epidermal growth factor receptor Homo sapiens 50-82 20338767-3 2010 In this study, we synthesized and examined a series of 5-carbon linker-containing mono-carbonyl analogues of curcumin with potent inhibitory activities against TNF-alpha and IL-6 release in LPS-stimulated RAW 264.7 macrophages. Carbon 57-63 tumor necrosis factor Homo sapiens 160-169 20338767-3 2010 In this study, we synthesized and examined a series of 5-carbon linker-containing mono-carbonyl analogues of curcumin with potent inhibitory activities against TNF-alpha and IL-6 release in LPS-stimulated RAW 264.7 macrophages. Carbon 57-63 interleukin 6 Homo sapiens 174-178 20154096-1 2010 The chloroplastic NAD kinase (NADK2) is reported to stimulate carbon and nitrogen assimilation in Arabidopsis (Arabidopsis thaliana), which is vulnerable to high light. Carbon 62-68 NAD kinase 2 Arabidopsis thaliana 30-35 20366546-0 2010 Body-centered tetragonal C4: a viable sp3 carbon allotrope. Carbon 42-48 Sp3 transcription factor Homo sapiens 38-41 20189213-5 2010 Biomass in strongly nitrogen-limited SBRs had higher baseline PHA contents in the SBR, but carbon-limited SBRs resulted usually in biomass with higher maximal PHA storage capacities. Carbon 91-97 lamin B receptor Homo sapiens 159-162 20189213-7 2010 For the microbial selection and biomass production stage of a PHA production process carbon limitation seems thus favourable and nutrient deficient wastewaters may consequently require supplementation with nutrients for the selection of a stable PHA storing biomass with a high storage capacity. Carbon 85-91 lamin B receptor Homo sapiens 62-65 20148593-0 2010 P-glycoprotein antibody functionalized carbon nanotube overcomes the multidrug resistance of human leukemia cells. Carbon 39-45 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 20026152-12 2010 Our results demonstrate that falcarindiol having conjugated diacetylene carbons covalently modifies the Cys151 residue in Keap1 and that the inactivation of Keap1 by falcarindiol leads to activation of the Nrf2/ARE pathway. Carbon 72-79 kelch like ECH associated protein 1 Homo sapiens 122-127 20026152-12 2010 Our results demonstrate that falcarindiol having conjugated diacetylene carbons covalently modifies the Cys151 residue in Keap1 and that the inactivation of Keap1 by falcarindiol leads to activation of the Nrf2/ARE pathway. Carbon 72-79 NFE2 like bZIP transcription factor 2 Homo sapiens 206-210 20148593-3 2010 In this work, the antibody of P-gp (anti-P-gp) functionalized water-soluble single-walled carbon nanotubes (Ap-SWNTs) loaded with doxorubicin (Dox), Dox/Ap-SWNTs, were synthesized for challenging the MDR of K562 human leukemia cells. Carbon 90-96 ATP binding cassette subfamily B member 1 Homo sapiens 30-34 20148593-3 2010 In this work, the antibody of P-gp (anti-P-gp) functionalized water-soluble single-walled carbon nanotubes (Ap-SWNTs) loaded with doxorubicin (Dox), Dox/Ap-SWNTs, were synthesized for challenging the MDR of K562 human leukemia cells. Carbon 90-96 ATP binding cassette subfamily B member 1 Homo sapiens 41-45 20175511-0 2010 Auxiliary-assisted palladium-catalyzed arylation and alkylation of sp2 and sp3 carbon-hydrogen bonds. Carbon 79-85 Sp3 transcription factor Homo sapiens 75-78 19926213-0 2010 Preconcentration of Cu(II), Fe(III) and Pb(II) with 2-((2-aminoethylamino)methyl)phenol-functionalized activated carbon followed by ICP-OES determination. Carbon 113-119 submaxillary gland androgen regulated protein 3B Homo sapiens 40-46 20194738-4 2010 Through random mutagenesis of one such hybrid MTS-COX2, we identified a single mutation in the first Cox2 transmembrane domain (W56 --> R) that (i) results in the cellular expression of a Cox2 variant with a molecular mass indicative of MTS cleavage, which (ii) supports growth of a cox2 mutant on a nonfermentable carbon source, and that (iii) partially restores cytochrome c oxidase-specific respiration by the mutant mitochondria. Carbon 318-324 cytochrome c oxidase subunit 2 Saccharomyces cerevisiae S288C 50-54 20194738-4 2010 Through random mutagenesis of one such hybrid MTS-COX2, we identified a single mutation in the first Cox2 transmembrane domain (W56 --> R) that (i) results in the cellular expression of a Cox2 variant with a molecular mass indicative of MTS cleavage, which (ii) supports growth of a cox2 mutant on a nonfermentable carbon source, and that (iii) partially restores cytochrome c oxidase-specific respiration by the mutant mitochondria. Carbon 318-324 cytochrome c oxidase subunit 2 Saccharomyces cerevisiae S288C 101-105 20194738-4 2010 Through random mutagenesis of one such hybrid MTS-COX2, we identified a single mutation in the first Cox2 transmembrane domain (W56 --> R) that (i) results in the cellular expression of a Cox2 variant with a molecular mass indicative of MTS cleavage, which (ii) supports growth of a cox2 mutant on a nonfermentable carbon source, and that (iii) partially restores cytochrome c oxidase-specific respiration by the mutant mitochondria. Carbon 318-324 cytochrome c oxidase subunit 2 Saccharomyces cerevisiae S288C 191-195 20194738-4 2010 Through random mutagenesis of one such hybrid MTS-COX2, we identified a single mutation in the first Cox2 transmembrane domain (W56 --> R) that (i) results in the cellular expression of a Cox2 variant with a molecular mass indicative of MTS cleavage, which (ii) supports growth of a cox2 mutant on a nonfermentable carbon source, and that (iii) partially restores cytochrome c oxidase-specific respiration by the mutant mitochondria. Carbon 318-324 cytochrome c oxidase subunit 2 Saccharomyces cerevisiae S288C 286-290 19926213-1 2010 A procedure for separation and preconcentration trace amount of Cu(II), Fe(III) and Pb(II) by 2-((2-aminoethylamino)methyl)phenol-functionalized activated carbon (AC-AMP) packed column has been proposed. Carbon 155-161 submaxillary gland androgen regulated protein 3B Homo sapiens 84-90 20032461-6 2010 Under PPARalpha activation, the classic reductive metabolic pathway of corticosterone was suppressed, whereas an alternative oxidative pathway was uncovered that leads to the sequential oxidation on carbon 21 resulting in HDOPA. Carbon 199-205 peroxisome proliferator activated receptor alpha Mus musculus 6-15 20479991-3 2010 The DHP synthesized by adopting the best reaction conditions was characterized by different analytical techniques (GPC, (13)C-NMR, (31)P-NMR and LC-MS) to elucidate its structure. Carbon 117-118 dihydropyrimidinase Homo sapiens 4-7 20043918-7 2010 The first molecule is a hydroxide ion (Wat1) that is bound as a bridge between the two metal ions and attacks the carbonyl carbon of the substrate. Carbon 114-120 MTOR associated protein, LST8 homolog Homo sapiens 39-43 20103110-0 2010 A disposable electrochemical immunosensor for carcinoembryonic antigen based on nano-Au/multi-walled carbon nanotubes-chitosans nanocomposite film modified glassy carbon electrode. Carbon 101-107 CEA cell adhesion molecule 3 Homo sapiens 46-70 19914765-5 2010 Carbon emissions from industrial energy use in Hangzhou were 7 Tg C/year. Carbon 0-6 transglutaminase 2 Homo sapiens 63-67 19948730-0 2010 Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos. Carbon 92-98 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like Mus musculus 44-51 20366836-1 2010 Motivated by recent experiments, we investigate how NO3-SWNT interactions become energetically favorable with varying oxidation state of a single-walled carbon nanotube (SWNT) using first-principles calculations. Carbon 153-159 NBL1, DAN family BMP antagonist Homo sapiens 52-55 20121156-2 2010 C-O insertion was found to be controlled by Pd-HOMO ArO-LUMO interaction, where C-Cl insertion is facilitated by the lower C-Cl TS distortion energy. Carbon 0-1 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 52-55 20121944-8 2010 The expression of DmTpc1p in Saccharomyces cerevisiaeTPC1 null mutant abolishes the growth defect on fermentable carbon sources. Carbon 113-119 Thiamine pyrophosphate carrier protein 1 Drosophila melanogaster 18-25 20307391-4 2010 Carbon nanotube electrodes are immobilized with fluorescently labeled bovine serum albumin (BSA) and analyzed with fluorescence microscopy to demonstrate their biocompatibility. Carbon 0-6 albumin Homo sapiens 77-90 19913088-3 2010 The reflection mode in the confocal laser scanning microscope was used to image multi-walled carbon nanotubes (MWCNT) in human neonatal epidermal keratinocytes (HEK) stained with the cytoskeleton protein F-actin. Carbon 93-99 EPH receptor A3 Homo sapiens 161-164 19782471-5 2010 It was found that ettringite and C-S-H gel were principally responsible for the strength development of TSC mortars with curing time. Carbon 33-34 TSC complex subunit 1 Homo sapiens 104-107 20103110-0 2010 A disposable electrochemical immunosensor for carcinoembryonic antigen based on nano-Au/multi-walled carbon nanotubes-chitosans nanocomposite film modified glassy carbon electrode. Carbon 163-169 CEA cell adhesion molecule 3 Homo sapiens 46-70 20103110-1 2010 In this paper, a disposable electrochemical immunosensor for the detection of carcinoembryonic antigen (CEA) based on Au nanoparticles (AuNPs)/multi-walled carbon nanotubes (MWCNTs)-chitosans (Chits) composite film was developed. Carbon 156-162 CEA cell adhesion molecule 3 Homo sapiens 78-102 20103110-1 2010 In this paper, a disposable electrochemical immunosensor for the detection of carcinoembryonic antigen (CEA) based on Au nanoparticles (AuNPs)/multi-walled carbon nanotubes (MWCNTs)-chitosans (Chits) composite film was developed. Carbon 156-162 CEA cell adhesion molecule 3 Homo sapiens 104-107 19937002-1 2010 A commercially available screen-printed carbon electrode coated with an ex situ deposited bismuth film (BiSPCE) has been applied to the determination of Pb(II) and Zn(II) ions in tap water (Barcelona water distribution network) by means of stripping voltammetry (SV) and stripping chronopotentiometry (SCP). Carbon 40-46 submaxillary gland androgen regulated protein 3B Homo sapiens 153-159 19733130-1 2010 In this paper, an acetylcholinesterase (AChE)/dendrimers polyamidoamine (PAMAM)-Au/Carbon nanotubes (CNTs) multilayer modified electrode based on LbL self-assembled technique was employed in the detection of carbofuran in samples. Carbon 83-89 acetylcholinesterase (Cartwright blood group) Homo sapiens 18-38 19733130-1 2010 In this paper, an acetylcholinesterase (AChE)/dendrimers polyamidoamine (PAMAM)-Au/Carbon nanotubes (CNTs) multilayer modified electrode based on LbL self-assembled technique was employed in the detection of carbofuran in samples. Carbon 83-89 acetylcholinesterase (Cartwright blood group) Homo sapiens 40-44 19777584-1 2010 The intracellular metabolic fluxes through the central carbon pathways in the bioprocess for recombinant human erythropoietin (rHuEPO) production by Pichia pastoris (Mut(+)) were calculated to investigate the metabolic effects of dual carbon sources (methanol/sorbitol) and the methanol feed rate, and to obtain a deeper understanding of the regulatory circuitry of P. pastoris, using the established stoichiometry-based model containing 102 metabolites and 141 reaction fluxes. Carbon 55-61 erythropoietin Homo sapiens 111-125 20056426-3 2010 Compound 8c, berberine linked with phenol by a 4-carbon spacer, showed the most potent inhibition of AChE. Carbon 49-55 acetylcholinesterase (Cartwright blood group) Homo sapiens 101-105 21069147-8 2010 Element emission ratios between the dopant metals and the carbon and sulfur protein constituents allow for concentration independent determinations of metal binding into Tf. Carbon 58-64 transferrin Homo sapiens 170-172 20030379-1 2010 A single-chamber microbial electrolysis cell (MEC) that used a high density of nonmetal-catalyst carbon fibers as the anode achieved high volumetric current densities from 1470 +/- 60 to 1630 +/- 50 A/m(3) for a hydraulic retention time of 1.6-6.5 h. The high current density was driven by a large anode surface area and corresponded to a volumetric chemical oxygen demand (COD)-removal rate of 27-49 kg COD/m(3).d. Carbon 97-103 C-C motif chemokine ligand 28 Homo sapiens 46-49 19879126-4 2010 An Immunoglobin A (IgA) immunosensor was constructed by the covalent bonding of IgA antibody molecules with the CSA aided by large numbers of carboxyl groups on the surface of carbon spheres. Carbon 176-182 CD79a molecule Homo sapiens 3-17 20018599-5 2010 Similarly, native starch granules prelabeled in either the carbon-6 or carbon-3 position were also dephosphorylated by AtSEX4. Carbon 59-65 dual specificity protein phosphatase (DsPTP1) family protein Arabidopsis thaliana 119-125 20018599-5 2010 Similarly, native starch granules prelabeled in either the carbon-6 or carbon-3 position were also dephosphorylated by AtSEX4. Carbon 71-77 dual specificity protein phosphatase (DsPTP1) family protein Arabidopsis thaliana 119-125 19969375-2 2010 Variable levels of components of one-carbon metabolism (folic acid and vitamin B12) and consequent altered levels of homocysteine and phospholipid docosahexaenoic acid (DHA) have been independently reported, mostly in medicated patients. Carbon 37-43 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 79-82 19969375-7 2010 This study, using a unique cohort, provided a broader mechanism (disturbed folic acid-vitamin B12-DHA balance) of altered one-carbon metabolism and one of its key consequential components, an increased homocysteine level that together with cortisol, can contribute to the neuropathology of psychosis. Carbon 126-132 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 94-97 20641630-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Carbon 19-20 gastrin releasing peptide receptor Homo sapiens 256-260 20000485-5 2010 The loss of carbon-bound CN(-) ligands from [Cr(CN)(6)](3-) occurs on a sufficiently slow time-scale for observation of varying degrees of cyanide linkage isomerism in the trigonal bipyramidal complex {[Co(tmphen)(2)](3)[Cr(CN)(6)](2)}; the study was aided by the use of different Co(II) starting materials. Carbon 12-18 mitochondrially encoded cytochrome c oxidase II Homo sapiens 281-287 19879126-4 2010 An Immunoglobin A (IgA) immunosensor was constructed by the covalent bonding of IgA antibody molecules with the CSA aided by large numbers of carboxyl groups on the surface of carbon spheres. Carbon 176-182 CD79a molecule Homo sapiens 19-22 19946151-9 2010 Vacuum annealing of the CNP tips at temperatures up to 2000 degrees C yields graphitic carbon structures with an increase in conductivity of two orders of magnitude. Carbon 87-93 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 24-27 20005456-13 2010 Furthermore, we found that irradiation with C-ions induced cellular senescence in a human glioma cell line lacking functional p53. Carbon 44-45 tumor protein p53 Homo sapiens 126-129 19720509-2 2010 Using immobilization technique, we have prepared human serum albumin (HSA) modified glassy carbon electrode (GCE) and employed it to probe the mode of interaction between antidepressant drug, buzepide methiodide (BZP) and HSA. Carbon 91-97 albumin Homo sapiens 55-68 19799901-12 2010 RNA interference indicates that the polyI:C-induced PGLYRP-2 was dramatically blocked in the cells transfected with siRNA-TRIF but neither siRNA-MyD88 nor the negative control siRNA-F. Carbon 42-43 TIR domain containing adaptor molecule 1 Homo sapiens 122-126 20336500-4 2010 The two recombinant strains grown on a mineral medium with 1 % chicken feather as source of energy, carbon and nitrogen exhibited higher proteolytic activity ( approximately 6-fold and 2.4-fold higher for strains 23/1 (p5.2) and 6/2 (p5.2), respectively. Carbon 100-106 protein kinase C and casein kinase substrate in neurons 2 Gallus gallus 219-223 22443622-1 2010 A previous study showed that long-chain n-3 polyunsaturated fatty acids (LCn-3PUFA; >18 carbons n-3) exert an anabolic effect on protein metabolism through the upregulation of insulin sensitivity and activation of the insulin signaling pathway. Carbon 91-98 insulin Homo sapiens 179-186 22443622-1 2010 A previous study showed that long-chain n-3 polyunsaturated fatty acids (LCn-3PUFA; >18 carbons n-3) exert an anabolic effect on protein metabolism through the upregulation of insulin sensitivity and activation of the insulin signaling pathway. Carbon 91-98 insulin Homo sapiens 221-228 20065523-11 2010 The methodology relies on the reductive properties of the matrix 1,5-diaminonaphtalene (1,5-DAN) which appears to be able to selectively reduce the double carbon-carbon bond belonging to the seventh amino acid. Carbon 155-161 NBL1, DAN family BMP antagonist Homo sapiens 92-95 20065523-11 2010 The methodology relies on the reductive properties of the matrix 1,5-diaminonaphtalene (1,5-DAN) which appears to be able to selectively reduce the double carbon-carbon bond belonging to the seventh amino acid. Carbon 162-168 NBL1, DAN family BMP antagonist Homo sapiens 92-95 20065523-15 2010 More generally, 1,5-DAN allows the selective reduction of double carbon-carbon bonds. Carbon 65-71 NBL1, DAN family BMP antagonist Homo sapiens 20-23 20065523-15 2010 More generally, 1,5-DAN allows the selective reduction of double carbon-carbon bonds. Carbon 72-78 NBL1, DAN family BMP antagonist Homo sapiens 20-23 20185925-8 2010 RESULTS: Costimulation with TNF-alpha and Th2 cytokines (IL-4, IL-13) or with poly(I:C) and Th2 cytokines (IL-4, IL-13) induced TARC production by nasal (polyp and normal) fibroblasts. Carbon 9-10 tumor necrosis factor Homo sapiens 28-37 20185925-8 2010 RESULTS: Costimulation with TNF-alpha and Th2 cytokines (IL-4, IL-13) or with poly(I:C) and Th2 cytokines (IL-4, IL-13) induced TARC production by nasal (polyp and normal) fibroblasts. Carbon 9-10 interleukin 4 Homo sapiens 57-61 20185925-8 2010 RESULTS: Costimulation with TNF-alpha and Th2 cytokines (IL-4, IL-13) or with poly(I:C) and Th2 cytokines (IL-4, IL-13) induced TARC production by nasal (polyp and normal) fibroblasts. Carbon 9-10 interleukin 13 Homo sapiens 63-68 20185925-8 2010 RESULTS: Costimulation with TNF-alpha and Th2 cytokines (IL-4, IL-13) or with poly(I:C) and Th2 cytokines (IL-4, IL-13) induced TARC production by nasal (polyp and normal) fibroblasts. Carbon 9-10 interleukin 4 Homo sapiens 107-111 20068353-4 2010 pykF silencing was detected by the following features: (a) impaired growth of the strain when pykA was also disrupted and when using ribose as a non-phosphotransferase system-transporting carbon source; (b) a pattern of reduced synthesis of the full-sized pykF mRNA, mediated by reverse transcription PCR, and (c) a significant decrease in PykF activity. Carbon 188-194 pyruvate kinase 1 Escherichia coli str. K-12 substr. MG1655 0-4 20617724-3 2010 Electrochemical degradation process was performed in an undivided cell and 92% PNP was removed corresponding to a 22% total organic carbon removal. Carbon 132-138 purine nucleoside phosphorylase Homo sapiens 79-82 20930296-2 2010 We previously demonstrated in the TgCRND8 mice strain, over-expressing human amyloid-beta protein precursor, that B vitamin deficiency causes alteration of one-carbon metabolism, together with unbalance of S-adenosylmethionine/S-adenosylhomocysteine levels, and is associated with AD like hallmarks as increased amyloid-beta plaque deposition, hyperhomocysteinemia, and oxidative stress. Carbon 160-166 amyloid beta precursor protein Homo sapiens 77-89 19887372-4 2010 Only the first 9-10 carbons of the sn2 acyl chain seem to interact intimately with the active site. Carbon 20-27 solute carrier family 38 member 5 Homo sapiens 35-38 19403283-8 2010 Carriers of the CETP TaqIB B2 allele had significantly higher HDL-C (p<0.0001) and significantly lower TC: HDL-C ratio (p<0.0001) compared to B1/B1 individuals. Carbon 0-1 cholesteryl ester transfer protein Homo sapiens 16-20 19851043-0 2010 Imaging of peripheral-type benzodiazepine receptor in tumor: carbon ion irradiation reduced the uptake of a positron emission tomography ligand [11C]DAC in tumor. Carbon 61-67 translocator protein Mus musculus 11-50 19851043-1 2010 We aimed to determine the effect of carbon ion irradiation on the uptake of N-benzyl-N-11C-methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([(11)C]DAC), a positron emission tomography (PET) ligand for the peripheral-type benzodiazepine receptor (PBR), in tumor cells and tumor-bearing mice. Carbon 36-42 translocator protein Mus musculus 227-266 19851043-1 2010 We aimed to determine the effect of carbon ion irradiation on the uptake of N-benzyl-N-11C-methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([(11)C]DAC), a positron emission tomography (PET) ligand for the peripheral-type benzodiazepine receptor (PBR), in tumor cells and tumor-bearing mice. Carbon 36-42 translocator protein Mus musculus 268-271 19851043-8 2010 In conclusion, [(11)C]DAC PET responded to the change in PBR expression in tumors caused by carbon ion irradiation in this study. Carbon 92-98 translocator protein Mus musculus 57-60 19403283-8 2010 Carriers of the CETP TaqIB B2 allele had significantly higher HDL-C (p<0.0001) and significantly lower TC: HDL-C ratio (p<0.0001) compared to B1/B1 individuals. Carbon 0-1 immunoglobulin kappa variable 7-3 (pseudogene) Homo sapiens 148-153 19929001-0 2009 Palladium-catalyzed hydroalkylation of styrenes with organozinc reagents to form carbon-carbon sp3-sp3 bonds under oxidative conditions. Carbon 81-87 Sp3 transcription factor Homo sapiens 95-98 19880612-3 2010 mvp1 mutants also exhibited a number of vacuole-related phenotypes, as demonstrated by defects in growth, utilization of stored carbon, gravitropic response, salt sensitivity, and specific susceptibility to the fungal necrotroph Alternaria brassicicola. Carbon 128-134 GDSL-like Lipase/Acylhydrolase superfamily protein Arabidopsis thaliana 0-4 22294918-3 2010 Screen-printed carbon electrodes (SPCEs) were used with acetylcholinesterase covalently bonded directly to its surface. Carbon 15-21 acetylcholinesterase (Cartwright blood group) Homo sapiens 56-76 20059067-4 2009 Selectivity in the fragmentation processes involving the C-Cl and C-F bonds are highlighted by the intensities of the C 1s to lowest unoccupied molecular orbital (LUMO) and LUMO+1 transitions measured on the CF(n)Cl(+) and CF(n)(+) yields. Carbon 57-58 complement C1s Homo sapiens 118-122 20344951-2 2010 MTM1 deletion results in decreased superoxide dismutase 2 activity, impaired mitochondrial functions and growth defect on nonfermentable carbon source. Carbon 137-143 Mtm1p Saccharomyces cerevisiae S288C 0-4 20344951-9 2010 RESULTS: We found transposon insertions in two genes were able to rescue the growth defect resulting from MTM1 deletion on nonfermentable carbon source. Carbon 138-144 Mtm1p Saccharomyces cerevisiae S288C 106-110 19692175-1 2009 A new method that utilizes ethylenediamine-modified multiwalled carbon nanotubes as a solid-phase extractant has been developed for simultaneous preconcentration of trace Cr(III), Fe(III) and Pb(II) prior to the measurement by inductively coupled plasma optical emission spectrometry. Carbon 64-70 submaxillary gland androgen regulated protein 3B Homo sapiens 192-198 19929001-0 2009 Palladium-catalyzed hydroalkylation of styrenes with organozinc reagents to form carbon-carbon sp3-sp3 bonds under oxidative conditions. Carbon 81-87 Sp3 transcription factor Homo sapiens 99-102 19954533-0 2009 Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice. Carbon 154-160 interleukin 1 beta Mus musculus 70-75 19632034-5 2009 The presence of externally added inorganic electron acceptors like NO2(-), NO3(-) and SO4(2-) was effective in anoxic ammonia oxidation, but failed to follow the reported anammox reaction"s stoichiometry in nitrogen removal in the presence of organic carbon. Carbon 251-257 NBL1, DAN family BMP antagonist Homo sapiens 75-78 20011012-2 2009 The Thermal and Near Infrared Sensor for Carbon Observation Fourier-Transform Spectrometer (TANSO-FTS) detects gas absorption spectra of the solar short wave infrared (SWIR) reflected on the Earth"s surface as well as of the thermal infrared radiated from the ground and the atmosphere. Carbon 41-47 AKT interacting protein Homo sapiens 98-101 19908794-1 2009 We fabricated carbon nanotube (CNT)- and nano-carbon (NC)-doped MgB2 using an in-situ process in order to improve the critical current density (J(c)) at high magnetic field. Carbon 14-20 secretoglobin family 2A member 1 Homo sapiens 64-68 19930465-1 2009 Tumor suppressor p53 plays a pivotal role in the regulation of cell fate determination in response to a variety of cellular stress including carbon source depletion. Carbon 141-147 tumor protein p53 Homo sapiens 17-20 19930465-9 2009 Taken together, our present findings suggest that p53 is transcriptionally regulated by CREB/phospho-AMPKalpha complex and thereby contributing to the induction of apoptosis under carbon source depletion. Carbon 180-186 tumor protein p53 Homo sapiens 50-53 19820096-6 2009 Thus, the loss of pykA from M. tuberculosis results in fatty acids being used principally for energy production, in contrast to the situation in the host when carbon from fatty acids is conserved through the glyoxylate cycle and gluconeogenesis; when an active pykA gene was introduced into M. bovis, the opposite effects occurred. Carbon 159-165 pyruvate kinase Mycobacterium tuberculosis H37Rv 18-22 19908794-1 2009 We fabricated carbon nanotube (CNT)- and nano-carbon (NC)-doped MgB2 using an in-situ process in order to improve the critical current density (J(c)) at high magnetic field. Carbon 46-52 secretoglobin family 2A member 1 Homo sapiens 64-68 19908794-5 2009 NC was more effective than CNT for carbon doping at the B site in MgB2 and, therefore, the NC-doped MgB2 samples had a lower critical temperature (T(c)) of 35.0-34.7 K than that of the CNT-doped samples (36.4-36.1 K). Carbon 35-41 secretoglobin family 2A member 1 Homo sapiens 66-70 19908794-5 2009 NC was more effective than CNT for carbon doping at the B site in MgB2 and, therefore, the NC-doped MgB2 samples had a lower critical temperature (T(c)) of 35.0-34.7 K than that of the CNT-doped samples (36.4-36.1 K). Carbon 35-41 secretoglobin family 2A member 1 Homo sapiens 100-104 19789176-6 2009 KEY RESULTS: This allele (SALK_038124, designated AtSUC2-4) has the hallmarks of previously described null alleles but, despite compromised carbon partitioning and growth, produces viable seeds. Carbon 140-146 sucrose-proton symporter 2 Arabidopsis thaliana 50-58 19930544-11 2009 The concentrations of interleukin-8 were significantly correlated with increasing organic carbon concentrations. Carbon 90-96 C-X-C motif chemokine ligand 8 Homo sapiens 22-35 19733574-4 2009 We have now determined the 1.95 A resolution crystal structure of recombinant human apoM expressed in Escherichia coli and made the unexpected discovery that apoM, although refolded from inclusion bodies, was in complex with fatty acids containing 14, 16 or 18 carbon atoms. Carbon 261-267 apolipoprotein M Homo sapiens 158-162 19863143-1 2009 Utilizing the lead-mediated arylation of beta-ketoesters and oxidative dearomatization/IMDA reaction as key steps, the two consecutive all-carbon quaternary centers (C-9 and C-10) were constructed in a stereoselective manner. Carbon 139-145 homeobox C10 Homo sapiens 174-178 19729169-0 2009 Adsorption of lysozyme on spherical mesoporous carbons (SMCs) replicated from colloidal silica arrays by chemical vapor deposition. Carbon 47-54 lysozyme Homo sapiens 14-22 19851564-6 2009 Using our extensive chemical bonding model that considers both sigma- and pi-bonding we also discuss why the AlB(9) and FeB(9)(-) species with octacoordinate Al and Fe are the global minima or low-lying isomers, as well as why carbon atom fits well into the central cavity of CAl(4)(2-) and CAl(5)(+). Carbon 227-233 albumin Homo sapiens 109-112 19674406-4 2009 Mutation of AtIPMDH1 leads to a significant reduction in the levels of free leucine and of glucosinolates with side chains of four or more carbons. Carbon 139-146 isopropylmalate dehydrogenase 3 Arabidopsis thaliana 12-20 19924949-1 2009 Temporal and spatial variability in the absorption coefficient (b(abs), Mm(-1)) and mass absorption efficiency (MAE, sigma(abs), m(2)g(-1)) of elemental carbon (EC) in atmospheric aerosols studied from urban, rural, and high-altitude sites is reported here. Carbon 153-159 solute carrier family 6 member 1 Homo sapiens 112-115 20101951-6 2009 Laser Raman spectroscopy was employed to analyze the microstructures of different carbon materials, and the results show that because sp3 and sp2 hybrid states of carbon atoms in resin carbon produced more vibration modes, the resin carbon also has higher normal spectral emissivity and better characteristics of heat radiation. Carbon 82-88 Sp3 transcription factor Homo sapiens 134-137 20101951-6 2009 Laser Raman spectroscopy was employed to analyze the microstructures of different carbon materials, and the results show that because sp3 and sp2 hybrid states of carbon atoms in resin carbon produced more vibration modes, the resin carbon also has higher normal spectral emissivity and better characteristics of heat radiation. Carbon 82-88 Sp2 transcription factor Homo sapiens 142-145 20101951-6 2009 Laser Raman spectroscopy was employed to analyze the microstructures of different carbon materials, and the results show that because sp3 and sp2 hybrid states of carbon atoms in resin carbon produced more vibration modes, the resin carbon also has higher normal spectral emissivity and better characteristics of heat radiation. Carbon 163-169 Sp3 transcription factor Homo sapiens 134-137 20101951-6 2009 Laser Raman spectroscopy was employed to analyze the microstructures of different carbon materials, and the results show that because sp3 and sp2 hybrid states of carbon atoms in resin carbon produced more vibration modes, the resin carbon also has higher normal spectral emissivity and better characteristics of heat radiation. Carbon 163-169 Sp2 transcription factor Homo sapiens 142-145 20101951-6 2009 Laser Raman spectroscopy was employed to analyze the microstructures of different carbon materials, and the results show that because sp3 and sp2 hybrid states of carbon atoms in resin carbon produced more vibration modes, the resin carbon also has higher normal spectral emissivity and better characteristics of heat radiation. Carbon 163-169 Sp3 transcription factor Homo sapiens 134-137 20101951-6 2009 Laser Raman spectroscopy was employed to analyze the microstructures of different carbon materials, and the results show that because sp3 and sp2 hybrid states of carbon atoms in resin carbon produced more vibration modes, the resin carbon also has higher normal spectral emissivity and better characteristics of heat radiation. Carbon 163-169 Sp2 transcription factor Homo sapiens 142-145 20101951-6 2009 Laser Raman spectroscopy was employed to analyze the microstructures of different carbon materials, and the results show that because sp3 and sp2 hybrid states of carbon atoms in resin carbon produced more vibration modes, the resin carbon also has higher normal spectral emissivity and better characteristics of heat radiation. Carbon 163-169 Sp3 transcription factor Homo sapiens 134-137 20101951-6 2009 Laser Raman spectroscopy was employed to analyze the microstructures of different carbon materials, and the results show that because sp3 and sp2 hybrid states of carbon atoms in resin carbon produced more vibration modes, the resin carbon also has higher normal spectral emissivity and better characteristics of heat radiation. Carbon 163-169 Sp2 transcription factor Homo sapiens 142-145 19619160-10 2009 Taken together, these findings indicate that KCS20 and KCS2/DAISY are functionally redundant in the two-carbon elongation to C(22) VLCFA that is required for cuticular wax and root suberin biosynthesis. Carbon 104-110 3-ketoacyl-CoA synthase 2 Arabidopsis thaliana 45-49 19800043-2 2009 Bioassay-guided screening of mouse tissue extracts found that natural fatty acids of a certain carbon length and level of unsaturation could activate the mouse orphan nuclear receptor, testicular orphan receptor 4 (TR4). Carbon 95-101 nuclear receptor subfamily 2, group C, member 2 Mus musculus 215-218 19666043-8 2009 However, evidence on the formation of carbon-centered radicals in the presence of Fe2+ was obtained by ESR spin-trapping. Carbon 38-44 esterase 5 regulator Mus musculus 103-106 19809653-1 2009 PPh3-catalyzed alpha-addition reactions of 1-(o-hydroxyaryl)-1,3-diketones to terminal alkynoates involving carbon-carbon bond cleavage to give multifunctional vinylesters are described. Carbon 108-114 caveolin 1 Homo sapiens 0-4 19809653-1 2009 PPh3-catalyzed alpha-addition reactions of 1-(o-hydroxyaryl)-1,3-diketones to terminal alkynoates involving carbon-carbon bond cleavage to give multifunctional vinylesters are described. Carbon 115-121 caveolin 1 Homo sapiens 0-4 19671704-4 2009 Absorption, resonance Raman and infrared spectroscopy, and molecular modeling of the Te-PixJ GAF (cGMP phosphodiesterase/adenyl cyclase/FhlA) domain assembled with phycocyanobilin are consistent with attachments to the C3(1) carbon of the ethylidene side chain and the C4 or C5 carbons in the A-B methine bridge to generate a double thioether-linked phycoviolobilin-type chromophore. Carbon 225-231 adenylate cyclase 1 Homo sapiens 121-135 19815515-6 2009 Furthermore, simulations with various water models, including TIP3P, TIP4P, and SPC/E, show that the transduction capability of the Y-shaped carbon nanotubes is very robust at room temperature, with the interference between branch signals negligible. Carbon 141-147 proline rich protein gene cluster Homo sapiens 80-83 19671704-4 2009 Absorption, resonance Raman and infrared spectroscopy, and molecular modeling of the Te-PixJ GAF (cGMP phosphodiesterase/adenyl cyclase/FhlA) domain assembled with phycocyanobilin are consistent with attachments to the C3(1) carbon of the ethylidene side chain and the C4 or C5 carbons in the A-B methine bridge to generate a double thioether-linked phycoviolobilin-type chromophore. Carbon 278-285 adenylate cyclase 1 Homo sapiens 121-135 19821630-3 2009 We show that relatively short (C18) carbon tails are insufficient to provide stabilization. Carbon 36-42 Bardet-Biedl syndrome 9 Homo sapiens 31-34 19687010-1 2009 The CYP7B1 cytochrome P450 enzyme hydroxylates carbons 6 and 7 of the B ring of oxysterols and steroids. Carbon 47-54 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 4-10 19759955-3 2009 Bridge cleavage reactions of 8 gave [PdCl(7-H)(L)] with L trans to carbon when L = PPh3 or 7 and cis to carbon when L = N-heterocyclic carbene. Carbon 67-73 caveolin 1 Homo sapiens 83-87 19535230-5 2009 The method has been applied to bovine serum albumin and cytochrome C adsorbed on an activated carbon. Carbon 94-100 albumin Homo sapiens 38-51 19535230-5 2009 The method has been applied to bovine serum albumin and cytochrome C adsorbed on an activated carbon. Carbon 94-100 cytochrome c, somatic Homo sapiens 56-68 19875056-0 2009 Intracellular reactions affecting 2-amino-4-([(11)C]methylthio)butyric acid ([(11)C]methionine) response to carbon ion radiotherapy in C10 glioma cells. Carbon 108-114 homeobox C10 Homo sapiens 135-138 19875056-2 2009 METHODS: After irradiation of cultured (3 Gy) or xenografted C10 glioma cells (25 Gy) using a carbon ion beam, the accumulation of [(14)C]Met and [(125)I]IMT in the tumors was investigated. Carbon 94-100 homeobox C10 Homo sapiens 61-64 19875056-2 2009 METHODS: After irradiation of cultured (3 Gy) or xenografted C10 glioma cells (25 Gy) using a carbon ion beam, the accumulation of [(14)C]Met and [(125)I]IMT in the tumors was investigated. Carbon 94-100 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 136-141 19875056-4 2009 RESULTS: [(14)C]Met provided earlier responses to the carbon ion beam irradiation than [(125)I]IMT in both cultured and xenografted tumors. Carbon 54-60 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 14-19 19908442-3 2009 In this work, iron filled carbon nanotubes non-covalently functionalized by human serum albumin are studied as potential agents for hyperthermia. Carbon 26-32 albumin Homo sapiens 82-95 19725532-3 2009 This was explained in terms of the greater degree of hydrophobicity of the C18 carbon chain requiring a significantly higher concentration of surfactant to be present on the surface before any further adsorption can occur. Carbon 79-85 Bardet-Biedl syndrome 9 Homo sapiens 75-78 19740668-2 2009 Balanced serotonin/norepinephrine reuptake inhibitors (SNRIs) (i.e., (R)- and (S)-norduloxetine) were chemically linked to a PDE4 inhibitor via a five carbon bridge. Carbon 151-157 phosphodiesterase 4A Homo sapiens 125-129 19799784-0 2009 Anti-HER2 IgY antibody-functionalized single-walled carbon nanotubes for detection and selective destruction of breast cancer cells. Carbon 52-58 erb-b2 receptor tyrosine kinase 2 Homo sapiens 5-9 19801835-5 2009 In addition, an accelerated model of IgA nephropathy was experimentally induced in ddY mice by oral administration of bovine serum albumin, followed by reticuloendothelial blocking by colloidal carbon injection and heminephrectomy. Carbon 194-200 CD79A antigen (immunoglobulin-associated alpha) Mus musculus 37-40 19699402-1 2009 A novel method that utilizes 1-(2-formamidoethyl)-3-phenylurea-modified activated carbon (AC-1-(2-formamidoethyl)-3-phenylurea) as a solid-phase extractant has been developed for simultaneous preconcentration of trace Cr(III), Cu(II), Fe(III) and Pb(II) prior to the measurement by inductively coupled plasma atomic emission spectrometry (ICP-AES). Carbon 82-88 submaxillary gland androgen regulated protein 3B Homo sapiens 247-253 19720172-0 2009 A carbon nanotubes assisted strategy for insulin detection and insulin proteolysis assay. Carbon 2-8 insulin Homo sapiens 41-48 19720172-0 2009 A carbon nanotubes assisted strategy for insulin detection and insulin proteolysis assay. Carbon 2-8 insulin Homo sapiens 63-70 19720172-1 2009 The carbon nanotubes (CNTs) assisted strategy has been proposed for insulin sensing and insulin proteolysis analysis. Carbon 4-10 insulin Homo sapiens 68-75 19720172-1 2009 The carbon nanotubes (CNTs) assisted strategy has been proposed for insulin sensing and insulin proteolysis analysis. Carbon 4-10 insulin Homo sapiens 88-95 19756312-0 2009 Carbon nanotubes as a protein toxin transporter for selective HER2-positive breast cancer cell destruction. Carbon 0-6 erb-b2 receptor tyrosine kinase 2 Homo sapiens 62-66 19950512-1 2009 Multi-walled carbon nanotube/polysulfone soft composites (MWCNT/PSf) prepared via phase inversion are a novel platform for electrochemical and electroanalytical purposes with practical applications in the design of screen-printed electrodes for electrochemical sensing. Carbon 13-19 insulin like growth factor binding protein 7 Homo sapiens 64-67 19701101-5 2009 RESULTS: Increases in black carbon and pm2.5 were associated with increases in blood pressure, heart rate, endothelin-1, vascular endothelial growth factor, and oxidative stress marker thiobarbituric acid reactive substances, and a decrease in brachial artery diameter (P < 0.05). Carbon 28-34 endothelin 1 Homo sapiens 107-119 19527682-7 2009 (13)C-MAS-NMR showed that T(1) values were decreased when Bax-C was incorporated into the lipid vesicles and this reduction affected similarly to carbons located in different regions of the membrane when the only phospholipid present was phosphatidylcholine. Carbon 146-153 BCL2 associated X, apoptosis regulator Homo sapiens 58-63 19540550-6 2009 Carbon nanotubes had high affinity for AChE adsorption, the highest being SWCNT (94%). Carbon 0-6 acetylcholinesterase (Cartwright blood group) Homo sapiens 39-43 19540550-10 2009 AChE inhibition by bulk Cu and activated carbon particles was also measured for comparison, showing that the inhibition by bulk particles was lower than their counterpart nanoparticles. Carbon 41-47 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 19540550-11 2009 For bulk Cu particles, AChE inhibition was primarily caused by dissolved ions, but mainly by adsorption for activated carbon. Carbon 118-124 acetylcholinesterase (Cartwright blood group) Homo sapiens 23-27 19540550-12 2009 AChE inhibition by Cu, Cu-C, MWCNT and SWCNT had dose-response relationships, and their median inhibitory concentrations (IC(50)) were 4, 17, 156 and 96mgL(-1), respectively, showing that these nanoparticles may have neurotoxicity and AChE may have potential to be used as a biomarker for nanoparticles. Carbon 39-44 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 19540550-12 2009 AChE inhibition by Cu, Cu-C, MWCNT and SWCNT had dose-response relationships, and their median inhibitory concentrations (IC(50)) were 4, 17, 156 and 96mgL(-1), respectively, showing that these nanoparticles may have neurotoxicity and AChE may have potential to be used as a biomarker for nanoparticles. Carbon 39-44 acetylcholinesterase (Cartwright blood group) Homo sapiens 235-239 19701101-5 2009 RESULTS: Increases in black carbon and pm2.5 were associated with increases in blood pressure, heart rate, endothelin-1, vascular endothelial growth factor, and oxidative stress marker thiobarbituric acid reactive substances, and a decrease in brachial artery diameter (P < 0.05). Carbon 28-34 vascular endothelial growth factor A Homo sapiens 121-155 19602173-2 2009 Previous work has suggested that the level of DGAT activity may have a substantial effect on the flow of carbon into triacylglycerol, implying that the enzyme may represent a promising target for seed oil modification through biotechnological approaches. Carbon 105-111 diacylglycerol O-acyltransferase 1-like Brassica napus 46-50 19524666-11 2009 We conclude that a functional emerin-lamin A/C complex is required for cell spreading and proliferation, possibly acting through ERK1/2 signalling. Carbon 45-46 mitogen-activated protein kinase 3 Homo sapiens 129-135 19587098-0 2009 Pleiotropic modulation of carbon and nitrogen metabolism in Arabidopsis plants overexpressing the NAD kinase2 gene. Carbon 26-32 NAD kinase 2 Arabidopsis thaliana 98-109 19587098-7 2009 These results indicate that overexpression of NADK2 either directly or indirectly stimulates carbon and nitrogen assimilation in Arabidopsis under restricted conditions. Carbon 93-99 NAD kinase 2 Arabidopsis thaliana 46-51 19723057-9 2009 Thus, the electrophilic carbon center located in the alpha,beta-unsaturated carbonyl moiety of the cyclopentenone ring might be critical for the control of DNA-binding activity as well as cellular levels of p53 by 15d-PGJ(2). Carbon 24-30 tumor protein p53 Homo sapiens 207-210 19523823-4 2009 Their synthesis and screening for possible inhibitors of angiotensin-converting enzyme (ACE) revealed that increase in the backbone chain length by one carbon atom results in a sudden decrease in their activity. Carbon 152-158 angiotensin I converting enzyme Homo sapiens 88-91 19469501-9 2009 In those reactions, the key mechanistic steps require hydrogen abstraction from a beta-carbon of the hydrocarbon chain (the second when counting away from the surface), and selectivity is defined by steric considerations around the different hydrogens available at those positions. Carbon 87-93 amyloid beta precursor protein Homo sapiens 80-86 19684852-4 2009 To investigate the potential preclinical relevance, K562 cells were transiently transfected with the siRNA targeting cyclin A(2) by functionalized single wall carbon nanotubes. Carbon 159-165 cyclin A2 Homo sapiens 117-127 19439417-1 2009 The light-activated enzyme NADPH-protochlorophyllide oxidoreductase (POR) catalyzes the trans addition of hydrogen across the C-17-C-18 double bond of protochlorophyllide (Pchlide), a key step in chlorophyll biosynthesis. Carbon 126-127 cytochrome p450 oxidoreductase Homo sapiens 27-67 19392700-3 2009 Mutations in LACS1 reduced the amount of wax in all chemical classes on the stem and leaf, except in the very long-chain fatty acid (VLCFA) class wherein acids longer than 24 carbons (C(24)) were elevated more than 155%. Carbon 175-182 AMP-dependent synthetase and ligase family protein Arabidopsis thaliana 13-18 19283452-1 2009 BACKGROUND: The impact of STAT-3 expression on the apoptosis of human hepatomas cell SMMC-7721 line induced by X-ray and carbon ion irradiations was investigated. Carbon 121-127 signal transducer and activator of transcription 3 Homo sapiens 26-32 19283452-8 2009 The carbon ion irradiation induced cell apoptosis and significantly promoted the expression of STAT-3 gene compared with the X-ray irradiation. Carbon 4-10 signal transducer and activator of transcription 3 Homo sapiens 95-101 18682255-8 2009 Smaller effects were also seen for one-carbon metabolism genes choline dehydrogenase (CHDH) (rs9001, rs7626693) and 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) (rs1801394) and genes involved in reduction reactions, glutaredoxin (GLRX) (rs3822751) and peroxiredoxin 2 (PRDX2) (rs10427027, rs12151144). Carbon 39-45 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 154-181 18682255-8 2009 Smaller effects were also seen for one-carbon metabolism genes choline dehydrogenase (CHDH) (rs9001, rs7626693) and 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) (rs1801394) and genes involved in reduction reactions, glutaredoxin (GLRX) (rs3822751) and peroxiredoxin 2 (PRDX2) (rs10427027, rs12151144). Carbon 39-45 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 183-187 18682255-8 2009 Smaller effects were also seen for one-carbon metabolism genes choline dehydrogenase (CHDH) (rs9001, rs7626693) and 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) (rs1801394) and genes involved in reduction reactions, glutaredoxin (GLRX) (rs3822751) and peroxiredoxin 2 (PRDX2) (rs10427027, rs12151144). Carbon 39-45 peroxiredoxin 2 Homo sapiens 280-295 18682255-8 2009 Smaller effects were also seen for one-carbon metabolism genes choline dehydrogenase (CHDH) (rs9001, rs7626693) and 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) (rs1801394) and genes involved in reduction reactions, glutaredoxin (GLRX) (rs3822751) and peroxiredoxin 2 (PRDX2) (rs10427027, rs12151144). Carbon 39-45 peroxiredoxin 2 Homo sapiens 297-302 19566103-3 2009 Herein, we report the one-pot synthesis of Pt and Pt-Pb nanoparticles incorporated into the pores of mesoporous niobium oxide-carbon composites. Carbon 126-132 protein tyrosine phosphatase receptor type B Homo sapiens 50-55 19439417-1 2009 The light-activated enzyme NADPH-protochlorophyllide oxidoreductase (POR) catalyzes the trans addition of hydrogen across the C-17-C-18 double bond of protochlorophyllide (Pchlide), a key step in chlorophyll biosynthesis. Carbon 126-127 cytochrome p450 oxidoreductase Homo sapiens 69-72 19439417-1 2009 The light-activated enzyme NADPH-protochlorophyllide oxidoreductase (POR) catalyzes the trans addition of hydrogen across the C-17-C-18 double bond of protochlorophyllide (Pchlide), a key step in chlorophyll biosynthesis. Carbon 130-132 cytochrome p450 oxidoreductase Homo sapiens 27-67 19439417-1 2009 The light-activated enzyme NADPH-protochlorophyllide oxidoreductase (POR) catalyzes the trans addition of hydrogen across the C-17-C-18 double bond of protochlorophyllide (Pchlide), a key step in chlorophyll biosynthesis. Carbon 130-132 cytochrome p450 oxidoreductase Homo sapiens 69-72 19085001-0 2009 High-efficiency transfer and expression of AdCMV-p53 in human cervix adenocarcinoma cells induced by subclinical-dose carbon beam radiation. Carbon 118-124 tumor protein p53 Homo sapiens 49-52 19090492-5 2009 This study provides evidence that the rapid and tenacious binding of albumin molecules to DLC materials tends to passivate the surfaces and to inhibit Fng adsorption, thus imparting thromboresistance to the carbon coatings by rendering the surfaces less adhesive and activating for platelets. Carbon 207-213 fibrinogen beta chain Homo sapiens 151-154 19320950-0 2009 The effect of carbon and nitrogen sources on bovicin HC5 production by Streptococcus bovis HC5. Carbon 14-20 CYCS pseudogene 1 Homo sapiens 91-94 19320950-4 2009 Streptococcus bovis HC5 produced bovicin using a variety of carbon and nitrogen sources. Carbon 60-66 CYCS pseudogene 1 Homo sapiens 20-23 19320950-9 2009 CONCLUSIONS: Streptococcus bovis HC5 is a versatile lactic acid bacterium that can utilize several carbon and nitrogen sources for bovicin HC5 production. Carbon 99-105 CYCS pseudogene 1 Homo sapiens 33-36 19320950-9 2009 CONCLUSIONS: Streptococcus bovis HC5 is a versatile lactic acid bacterium that can utilize several carbon and nitrogen sources for bovicin HC5 production. Carbon 99-105 CYCS pseudogene 1 Homo sapiens 139-142 19320950-11 2009 SIGNIFICANCE AND IMPACT OF THE STUDY: The use of agroindustrial residues as carbon sources could have an economical impact on bovicin HC5 production. Carbon 76-82 CYCS pseudogene 1 Homo sapiens 134-137 19085001-1 2009 PURPOSE: The aim of this study is to evaluate the effect of carbon-beam irradiation on adenovirus-mediated p53 transfer in human cervix adenocarcinoma. Carbon 60-66 tumor protein p53 Homo sapiens 107-110 19712949-8 2009 C-11 binds to BGAF, indicating that the Ile(72)-Thr(82) region is indeed a major interaction site on Glu1 involved in BGAF binding. Carbon 0-1 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic Zea mays 101-105 19447542-2 2009 In this work, coffee residue has been used as raw material in the preparation of powder activated carbon by the method of chemical activation with zinc chloride for the sorption of Pb(II) from dilute aqueous solutions. Carbon 98-104 submaxillary gland androgen regulated protein 3B Homo sapiens 181-187 19791508-2 2009 By comparing the interactions of each analogue with beta-tubulin, the structure-activity relationships are summarized as follow: C-2 benzoyl and taxane ring systems are the essential groups for microtubule binding, the improvements of bioactivity and bioavailability are dependent on the substituents at positions C-1, C-4, C-7, C-9, C-10, and C-14, whereas the C-13 side chain mainly provides a specific binding. Carbon 129-130 homeobox C10 Homo sapiens 334-338 19938498-4 2009 The IR spectra demonstrated that C18 was bonded to the surface of gold microspheres with the carbon content of 0.56%. Carbon 93-99 Bardet-Biedl syndrome 9 Homo sapiens 33-36 19376823-13 2009 AVAILABILITY: The C++ source code for SCARNA_LM and its experimental datasets are available at http://www.ncrna.org/software/scarna_lm/download. Carbon 18-21 RNANC Homo sapiens 106-111 19425580-2 2009 Product distributions for the reaction of glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) catalyzed by triosephosphate isomerase (TIM) in D(2)O at pD 7.0 in the presence of phosphite dianion and in its absence were determined by (1)H NMR spectroscopy. Carbon 70-76 triosephosphate isomerase 1 Homo sapiens 131-156 19425580-2 2009 Product distributions for the reaction of glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) catalyzed by triosephosphate isomerase (TIM) in D(2)O at pD 7.0 in the presence of phosphite dianion and in its absence were determined by (1)H NMR spectroscopy. Carbon 70-76 triosephosphate isomerase 1 Homo sapiens 158-161 19345570-0 2009 A nitrite biosensor based on the immobilization of cytochrome c on multi-walled carbon nanotubes-PAMAM-chitosan nanocomposite modified glass carbon electrode. Carbon 80-86 cytochrome c, somatic Homo sapiens 51-63 19345570-0 2009 A nitrite biosensor based on the immobilization of cytochrome c on multi-walled carbon nanotubes-PAMAM-chitosan nanocomposite modified glass carbon electrode. Carbon 141-147 cytochrome c, somatic Homo sapiens 51-63 19345570-1 2009 A novel nitrite biosensor was successfully prepared via immobilizing Cytochrome c (Cyt c) onto the multi-walled carbon nanotubes-poly(amidoamine) (PAMAM)-chitosan (MWNT-PAMAM-Chit) nanocomposite modified glass carbon electrode (GCE). Carbon 112-118 cytochrome c, somatic Homo sapiens 69-81 19345570-1 2009 A novel nitrite biosensor was successfully prepared via immobilizing Cytochrome c (Cyt c) onto the multi-walled carbon nanotubes-poly(amidoamine) (PAMAM)-chitosan (MWNT-PAMAM-Chit) nanocomposite modified glass carbon electrode (GCE). Carbon 112-118 cytochrome c, somatic Homo sapiens 83-88 19440050-8 2009 The two yeast PAS kinase homologs, Psk1 and Psk2, are activated by two stimuli, cell integrity stress and nonfermentative carbon sources. Carbon 122-128 serine/threonine protein kinase PSK1 Saccharomyces cerevisiae S288C 35-39 19345570-1 2009 A novel nitrite biosensor was successfully prepared via immobilizing Cytochrome c (Cyt c) onto the multi-walled carbon nanotubes-poly(amidoamine) (PAMAM)-chitosan (MWNT-PAMAM-Chit) nanocomposite modified glass carbon electrode (GCE). Carbon 210-216 cytochrome c, somatic Homo sapiens 69-81 19345570-1 2009 A novel nitrite biosensor was successfully prepared via immobilizing Cytochrome c (Cyt c) onto the multi-walled carbon nanotubes-poly(amidoamine) (PAMAM)-chitosan (MWNT-PAMAM-Chit) nanocomposite modified glass carbon electrode (GCE). Carbon 210-216 cytochrome c, somatic Homo sapiens 83-88 21582700-1 2009 In the title complex, [Co(C(22)H(24)N(2)O(4))] H(2)O, the Co(II) atom is in an almost square-planar coordination environment involv-ing two O and two N atoms from the Schiff base ligand. Carbon 23-24 mitochondrially encoded cytochrome c oxidase II Homo sapiens 58-64 19276076-8 2009 Mesangial cell cultures treated with poly(I:C) or tunicamycin in normal glucose media synthesized monocyte-adhesive hyaluronan matrices but with concurrent down-regulation of cyclin D3. Carbon 44-45 cyclin D3 Rattus norvegicus 175-184 19362210-0 2009 Direct electrochemistry of catalase at multiwalled carbon nanotubes-nafion in presence of needle shaped DDAB for H2O2 sensor. Carbon 51-57 catalase Homo sapiens 27-35 19362210-1 2009 The direct electrochemistry of catalase (CAT) at didodecyldimethylammonium bromide (DDAB) present on nafion dispersed multiwalled carbon nanotubes (MWCNTs-NF) modified glassy carbon electrode (GCE) has been reported. Carbon 130-136 catalase Homo sapiens 31-39 19362210-1 2009 The direct electrochemistry of catalase (CAT) at didodecyldimethylammonium bromide (DDAB) present on nafion dispersed multiwalled carbon nanotubes (MWCNTs-NF) modified glassy carbon electrode (GCE) has been reported. Carbon 130-136 catalase Homo sapiens 41-44 19362210-1 2009 The direct electrochemistry of catalase (CAT) at didodecyldimethylammonium bromide (DDAB) present on nafion dispersed multiwalled carbon nanotubes (MWCNTs-NF) modified glassy carbon electrode (GCE) has been reported. Carbon 175-181 catalase Homo sapiens 31-39 19362210-1 2009 The direct electrochemistry of catalase (CAT) at didodecyldimethylammonium bromide (DDAB) present on nafion dispersed multiwalled carbon nanotubes (MWCNTs-NF) modified glassy carbon electrode (GCE) has been reported. Carbon 175-181 catalase Homo sapiens 41-44 19329139-6 2009 The surface water with the highest total organic carbon concentration exhibited the most dramatic nitroaromatic loss from solution with tetryl, 1,3,5-TNB and TNT concentrations decreasing to below detection within 10d. Carbon 49-55 chromosome 16 open reading frame 82 Homo sapiens 158-161 19299007-10 2009 The materials may also suppress excessive inflammation by adsorption of the cytokine IL-8 into the porous, internal carbon structure. Carbon 116-122 C-X-C motif chemokine ligand 8 Homo sapiens 85-89 19353602-0 2009 Adsorption of insulin peptide on charged single-walled carbon nanotubes: significant role of ordered water molecules. Carbon 55-61 insulin Homo sapiens 14-21 19303822-6 2009 The colloidal rhodium was then used for electrochemical sensing of cytochrome c using glassy carbon electrode. Carbon 93-99 cytochrome c, somatic Homo sapiens 67-79 19303822-8 2009 Differential pulse voltammetric measurements of cytochrome c at the colloidal rhodium nanoparticles modified glassy carbon electrode showed a linear relationship with the oxidation peak currents in the concentration range of 100 nM to 3 microM of cytochrome c. Carbon 116-122 cytochrome c, somatic Homo sapiens 48-60 19303822-8 2009 Differential pulse voltammetric measurements of cytochrome c at the colloidal rhodium nanoparticles modified glassy carbon electrode showed a linear relationship with the oxidation peak currents in the concentration range of 100 nM to 3 microM of cytochrome c. Carbon 116-122 cytochrome c, somatic Homo sapiens 247-259 19456874-5 2009 Recent studies reveal that PIS1 expression is regulated at the level of transcription in response to carbon source, oxygen, and zinc. Carbon 101-107 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 27-31 19141536-0 2009 Knockdown of TRPC3 with siRNA coupled to carbon nanotubes results in decreased insulin-mediated glucose uptake in adult skeletal muscle cells. Carbon 41-47 transient receptor potential cation channel, subfamily C, member 3 Mus musculus 13-18 19141536-5 2009 Knockdown of TRPC3, using a novel technique based on small interfering RNA (siRNA) coupled to functionalized carbon nanotubes, resulted in pronounced (approximately 70%) decreases in OAG-induced Ca(2+) influx and insulin-mediated glucose uptake. Carbon 109-115 transient receptor potential cation channel, subfamily C, member 3 Mus musculus 13-18 19504943-0 2009 Nanostructured sp2-carbon infiltration of mesoporous silicon layers. Carbon 19-25 Sp2 transcription factor Homo sapiens 15-18 19319146-8 2009 Interestingly, administration of exogenous TGF-beta1 before CIP activated the TGF-beta/ALK5 pathway and reduced BBB permeability to (14)C-sucrose. Carbon 60-61 transforming growth factor, beta 1 Rattus norvegicus 43-52 19319146-8 2009 Interestingly, administration of exogenous TGF-beta1 before CIP activated the TGF-beta/ALK5 pathway and reduced BBB permeability to (14)C-sucrose. Carbon 60-61 transforming growth factor, beta 1 Rattus norvegicus 43-51 19504943-3 2009 Micro-Raman spectroscopy and Field Emission Gun Scanning Electron Microscopy (FEG-SEM) techniques showed that diamond nucleation density was very low whilst sp2 carbon permeated completely, even after 1 h deposition, the thickness of the PS layers that preserved their mesoporous columnar structure. Carbon 161-167 Sp2 transcription factor Homo sapiens 157-160 19269805-0 2009 Electrochemical biosensor for pesticides based on acetylcholinesterase immobilized on polyaniline deposited on vertically assembled carbon nanotubes wrapped with ssDNA. Carbon 132-138 acetylcholinesterase (Cartwright blood group) Homo sapiens 50-70 19530961-9 2009 Carriers of the APOA5 genotype TT-1131 (n = 154) benefited more from statin treatment when compared with the C-1131 allele carriers (n = 33) (Delta low-density lipoprotein cholesterol: -36.3 +/- 15.1% vs Delta low-density lipoprotein cholesterol: -29.9 +/- 12.5%; p < 0.005, Mann-Whitney test). Carbon 0-1 apolipoprotein A5 Homo sapiens 16-21 19452017-11 2009 Similarly, the poly(I:C)-induced activation of NFkappaB was decreased by both DEX and CsA, and the activation of IRF3 was reduced by DEX alone. Carbon 22-23 nuclear factor kappa B subunit 1 Homo sapiens 47-55 19544893-8 2009 The PCB bioaccumulation in marine clams was reduced when exposed to sediment treated with 2% AC in comparison to the control plot Field-deployed semi permeable membrane devices and polyethylene devices showed about 50% reduction in PCB uptake in AC-treated sediment and similar reduction in estimated pore-water PCB concentration. Carbon 93-95 pyruvate carboxylase Homo sapiens 4-7 19544893-8 2009 The PCB bioaccumulation in marine clams was reduced when exposed to sediment treated with 2% AC in comparison to the control plot Field-deployed semi permeable membrane devices and polyethylene devices showed about 50% reduction in PCB uptake in AC-treated sediment and similar reduction in estimated pore-water PCB concentration. Carbon 93-95 pyruvate carboxylase Homo sapiens 232-235 19544893-8 2009 The PCB bioaccumulation in marine clams was reduced when exposed to sediment treated with 2% AC in comparison to the control plot Field-deployed semi permeable membrane devices and polyethylene devices showed about 50% reduction in PCB uptake in AC-treated sediment and similar reduction in estimated pore-water PCB concentration. Carbon 93-95 pyruvate carboxylase Homo sapiens 232-235 19544893-8 2009 The PCB bioaccumulation in marine clams was reduced when exposed to sediment treated with 2% AC in comparison to the control plot Field-deployed semi permeable membrane devices and polyethylene devices showed about 50% reduction in PCB uptake in AC-treated sediment and similar reduction in estimated pore-water PCB concentration. Carbon 246-248 pyruvate carboxylase Homo sapiens 4-7 19544893-8 2009 The PCB bioaccumulation in marine clams was reduced when exposed to sediment treated with 2% AC in comparison to the control plot Field-deployed semi permeable membrane devices and polyethylene devices showed about 50% reduction in PCB uptake in AC-treated sediment and similar reduction in estimated pore-water PCB concentration. Carbon 246-248 pyruvate carboxylase Homo sapiens 232-235 19544893-8 2009 The PCB bioaccumulation in marine clams was reduced when exposed to sediment treated with 2% AC in comparison to the control plot Field-deployed semi permeable membrane devices and polyethylene devices showed about 50% reduction in PCB uptake in AC-treated sediment and similar reduction in estimated pore-water PCB concentration. Carbon 246-248 pyruvate carboxylase Homo sapiens 232-235 19544893-11 2009 Field-exposed AC after 18 months retained a strong stabilization capability to reduce aqueous equilibrium PCB concentrations by about 90%, which also supports the long-term effectiveness of AC in the field. Carbon 14-16 pyruvate carboxylase Homo sapiens 106-109 19544893-11 2009 Field-exposed AC after 18 months retained a strong stabilization capability to reduce aqueous equilibrium PCB concentrations by about 90%, which also supports the long-term effectiveness of AC in the field. Carbon 190-192 pyruvate carboxylase Homo sapiens 106-109 19479013-0 2009 Alkylphenol xenoestrogens with varying carbon chain lengths differentially and potently activate signaling and functional responses in GH3/B6/F10 somatomammotropes. Carbon 39-45 coagulation factor X Rattus norvegicus 135-145 19362238-0 2009 Different mechanisms of cell death in radiosensitive and radioresistant p53 mutated head and neck squamous cell carcinoma cell lines exposed to carbon ions and x-rays. Carbon 144-150 tumor protein p53 Homo sapiens 72-75 19424415-0 2009 Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. Carbon 20-26 serine/threonine protein kinase SCH9 Saccharomyces cerevisiae S288C 5-9 19232736-6 2009 The electrostatic interaction between C52 and R266 is critical for stabilizing the ferrous heme and its disruption leads to the facile formation of a 424nm (C-424) absorbing ferrous species, which is inactive, compared to the active 449nm ferrous species for wild-type CBS. Carbon 38-39 cystathionine beta-synthase Homo sapiens 269-272 19232736-8 2009 EXAFS studies on C-424 CBS are consistent with the presence of two axial N/O low Z scatters with only one being a rigid unit of a histidine residue while the other could be a solvent molecule, an oxygen atom from the peptide backbone or a side chain nitrogen. Carbon 17-18 cystathionine beta-synthase Homo sapiens 23-26 21475854-2 2009 It is characterized by abdominal obesity, elevated blood pressure, atherogenic dyslipidemia [high LDL-c (low density lipoprotein cholesterol) and low HDL-c (high density lipoprotein cholesterol)] and insulin resistance or glucose intolerance. Carbon 6-7 component of oligomeric golgi complex 2 Homo sapiens 98-103 19383711-0 2009 Gis1 is required for transcriptional reprogramming of carbon metabolism and the stress response during transition into stationary phase in yeast. Carbon 54-60 histone demethylase GIS1 Saccharomyces cerevisiae S288C 0-4 19383711-4 2009 In chemostat cultures, gis1 or rim15 mutant cells are outcompeted by their wild-type parents under conditions resembling the later stages of diauxie (glucose-limiting) and post-diauxie (ethanol as a carbon source). Carbon 199-205 histone demethylase GIS1 Saccharomyces cerevisiae S288C 23-27 19383711-4 2009 In chemostat cultures, gis1 or rim15 mutant cells are outcompeted by their wild-type parents under conditions resembling the later stages of diauxie (glucose-limiting) and post-diauxie (ethanol as a carbon source). Carbon 199-205 protein kinase RIM15 Saccharomyces cerevisiae S288C 31-36 19383711-6 2009 Further, we show that the sets of GIS1- and RIM15-dependent genes and the degree of their regulation change in response to the identity of the carbon source, suggesting the likely dynamics of gene regulation exerted by Rim15p and Gis1p during different phases of the transition into stationary phase. Carbon 143-149 histone demethylase GIS1 Saccharomyces cerevisiae S288C 34-38 19383711-6 2009 Further, we show that the sets of GIS1- and RIM15-dependent genes and the degree of their regulation change in response to the identity of the carbon source, suggesting the likely dynamics of gene regulation exerted by Rim15p and Gis1p during different phases of the transition into stationary phase. Carbon 143-149 protein kinase RIM15 Saccharomyces cerevisiae S288C 44-49 19383711-6 2009 Further, we show that the sets of GIS1- and RIM15-dependent genes and the degree of their regulation change in response to the identity of the carbon source, suggesting the likely dynamics of gene regulation exerted by Rim15p and Gis1p during different phases of the transition into stationary phase. Carbon 143-149 protein kinase RIM15 Saccharomyces cerevisiae S288C 219-225 19383711-6 2009 Further, we show that the sets of GIS1- and RIM15-dependent genes and the degree of their regulation change in response to the identity of the carbon source, suggesting the likely dynamics of gene regulation exerted by Rim15p and Gis1p during different phases of the transition into stationary phase. Carbon 143-149 histone demethylase GIS1 Saccharomyces cerevisiae S288C 230-235 19383711-7 2009 In particular, Rim15p is required for the expression of genes involved in gluconeogenesis/glycolysis and glycerol biosynthesis only when ethanol is used as the carbon source. Carbon 160-166 protein kinase RIM15 Saccharomyces cerevisiae S288C 15-21 19348451-6 2009 The C(60) contains H(2), and this provides an NMR signal upfield from TMS, well away from the rest of the spectrum. Carbon 4-5 PYD and CARD domain containing Homo sapiens 70-73 19275250-6 2009 (smif)FeN(TMS)(2) (4) is principally monomeric in solution, but reversibly dimerizes (K(eq) approximately 10(-4) M(-1)) via C-C bond formation in the azaallyl backbone to crystallize as {(TMS)(2)NFe}(2)(smif)(2) (4(2)). Carbon 124-125 decapping mRNA 1A Homo sapiens 1-5 19396142-6 2009 The three methods produce similar estimates of a net carbon sink in the range of 0.19-0.26 Pg carbon (PgC) per year, which is smaller than that in the conterminous United States but comparable to that in geographic Europe. Carbon 53-59 progastricsin Homo sapiens 102-105 32688647-2 2009 Our study showed that ear carbon sink was limited, and sugar was accumulated, hexokinase activities and levels of phosphorylated sugar were increased within the flag leaves, grain nitrogen sink capacity was enhanced, and flag leaf senescence was accelerated under elevated CO2. Carbon 26-32 hexokinase 1 Homo sapiens 78-88 19437977-1 2009 In this paper, a simple method for immobilization of acetylcholinesterase (AChE) on cysteamine assembled glassy carbon electrode coupled with gold nanoparticles (GNPs) was proposed and thus a sensitive, fast and stable amperometric biosensor for quantitative determination of monocrotophos was developed. Carbon 112-118 acetylcholinesterase (Cartwright blood group) Homo sapiens 53-73 19437977-1 2009 In this paper, a simple method for immobilization of acetylcholinesterase (AChE) on cysteamine assembled glassy carbon electrode coupled with gold nanoparticles (GNPs) was proposed and thus a sensitive, fast and stable amperometric biosensor for quantitative determination of monocrotophos was developed. Carbon 112-118 acetylcholinesterase (Cartwright blood group) Homo sapiens 75-79 20052401-0 2009 In Vivo Therapeutic Silencing of Hypoxia-Inducible Factor 1 Alpha (HIF-1alpha) Using Single-Walled Carbon Nanotubes Noncovalently Coated with siRNA. Carbon 99-105 hypoxia inducible factor 1 subunit alpha Homo sapiens 33-65 20052401-0 2009 In Vivo Therapeutic Silencing of Hypoxia-Inducible Factor 1 Alpha (HIF-1alpha) Using Single-Walled Carbon Nanotubes Noncovalently Coated with siRNA. Carbon 99-105 hypoxia inducible factor 1 subunit alpha Homo sapiens 67-77 19280122-7 2009 We show that this approach is successful in four different proteins including Ca2+-bound Calmodulin, Lysozyme, Ca2+-bound Troponin C, and Glutathione S-Transferase. Carbon 78-79 calmodulin 1 Homo sapiens 89-99 19275250-6 2009 (smif)FeN(TMS)(2) (4) is principally monomeric in solution, but reversibly dimerizes (K(eq) approximately 10(-4) M(-1)) via C-C bond formation in the azaallyl backbone to crystallize as {(TMS)(2)NFe}(2)(smif)(2) (4(2)). Carbon 124-125 PYD and CARD domain containing Homo sapiens 10-13 18754757-0 2009 The influence of carbon sources on recombinant-human- growth-hormone production by Pichia pastoris is dependent on phenotype: a comparison of Muts and Mut+ strains. Carbon 17-23 growth hormone 1 Homo sapiens 54-68 19038538-2 2009 Monoclonal anti-CEA antibodies (alphaCEA) were covalently immobilized on polyethyleneimine wrapped multiwalled carbon nanotubes screen-printed electrode. Carbon 111-117 CEA cell adhesion molecule 3 Homo sapiens 16-19 19111456-1 2009 We developed a simple strategy for designing a highly sensitive electrochemical biosensor for organophosphate pesticides (OPs) based on acetylcholinesterase (AChE) immobilized onto Au nanoparticles-polypyrrole nanowires composite film modifid glassy carbon electrode (labeled as AChE-Au-PPy/GCE). Carbon 250-256 acetylcholinesterase (Cartwright blood group) Homo sapiens 136-156 19111456-1 2009 We developed a simple strategy for designing a highly sensitive electrochemical biosensor for organophosphate pesticides (OPs) based on acetylcholinesterase (AChE) immobilized onto Au nanoparticles-polypyrrole nanowires composite film modifid glassy carbon electrode (labeled as AChE-Au-PPy/GCE). Carbon 250-256 acetylcholinesterase (Cartwright blood group) Homo sapiens 158-162 19114507-6 2009 The identification of these metabolites suggests a carbon addition at the C-3 position of hexadecane, with subsequent beta-oxidation and transformation reactions (chain elongation and C-10 methylation) that predominantly produce fatty acids with odd numbers of carbons. Carbon 51-57 homeobox C10 Homo sapiens 184-188 19210614-3 2009 These cells, termed 2Delta.YDC1, make sphingolipids containing exclusively dihydrosphingosine and an abnormally wide spectrum of fatty acids with between 18 and 26 carbon atoms. Carbon 164-170 alkaline dihydroceramidase Saccharomyces cerevisiae S288C 27-31 19159204-1 2009 We have developed a sensitive electrochemical immunoassay system for the detection of a protein tumor marker, carcinoembryonic antigen (CEA), that is based on a carbon nanoparticle (CNP)/poly(ethylene imine) (PEI)-modified screen-printed graphite electrode (CNP-PEI/SPGE) covered with anti-CEA antibodies. Carbon 161-167 CEA cell adhesion molecule 3 Homo sapiens 110-134 19054349-2 2009 The cloning and transgenic expression of one family member (STP13) enabled the manipulation of carbon (C) and nitrogen (N) metabolism in Arabidopsis. Carbon 95-101 Major facilitator superfamily protein Arabidopsis thaliana 60-65 19257783-0 2009 Formation of sp3-bonded carbon nanostructures by femtosecond laser excitation of graphite. Carbon 24-30 Sp3 transcription factor Homo sapiens 13-16 19214306-2 2009 Both C-Cl bonds of CH(2)Cl(2) are readily activated by CoCl(2) and metallic Zn allowing quantitative methylation of phosphines; unprecedented zwitterionic Co(ii) and Zn(ii) intermediates have been characterized which display alpha-metallated phosphoniums. Carbon 5-6 mitochondrially encoded cytochrome c oxidase II Homo sapiens 155-161 19214306-2 2009 Both C-Cl bonds of CH(2)Cl(2) are readily activated by CoCl(2) and metallic Zn allowing quantitative methylation of phosphines; unprecedented zwitterionic Co(ii) and Zn(ii) intermediates have been characterized which display alpha-metallated phosphoniums. Carbon 5-6 mitochondrially encoded cytochrome c oxidase II Homo sapiens 158-160 19185119-1 2009 In this paper, carbon nanofibers (CNFs) as a novel solid phase extraction sorbent were developed for speciation preconcentration and separation of inorganic arsenic species As(III) and As(V) prior to determination by inductively coupled plasma mass spectrometry (ICP-MS). Carbon 15-21 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 185-190 19159204-1 2009 We have developed a sensitive electrochemical immunoassay system for the detection of a protein tumor marker, carcinoembryonic antigen (CEA), that is based on a carbon nanoparticle (CNP)/poly(ethylene imine) (PEI)-modified screen-printed graphite electrode (CNP-PEI/SPGE) covered with anti-CEA antibodies. Carbon 161-167 CEA cell adhesion molecule 3 Homo sapiens 136-139 19402520-3 2009 The n-alkane homolog from C10 to C33 were detected with the major peak carbon numbers ranging from 23 to 25. Carbon 71-77 homeobox C10 Homo sapiens 26-29 19121628-0 2009 ROS and NF-kappaB are involved in upregulation of IL-8 in A549 cells exposed to multi-walled carbon nanotubes. Carbon 93-99 C-X-C motif chemokine ligand 8 Homo sapiens 50-54 19056732-4 2009 Here we show that the yeast Mediator subunit Gal11p/MED15 and its activator-targeted KIX domain plays a critical role in fatty acid-dependent transcriptional regulation of fatty acid beta-oxidation and peroxisomal genes by Oaf1p and for the ability of yeast to utilize fatty acids as a sole carbon source. Carbon 291-297 oleate-activated transcription factor OAF1 Saccharomyces cerevisiae S288C 223-228 18848983-6 2009 Increased amounts of TNF-alpha and IL-6 were also evident in SDR DC cultures stimulated with poly(I:C). Carbon 99-101 tumor necrosis factor Mus musculus 21-30 19143513-1 2009 Addition of the sp-C-H bond of triisopropylsilylacetylene to the carbon-carbon double bonds of styrenes bearing functional groups proceeded efficiently at room temperature in the presence of 3 mol % of Ni(cod)(2) with a PMePh(2) ligand. Carbon 65-71 surfactant protein C Homo sapiens 16-20 19143513-1 2009 Addition of the sp-C-H bond of triisopropylsilylacetylene to the carbon-carbon double bonds of styrenes bearing functional groups proceeded efficiently at room temperature in the presence of 3 mol % of Ni(cod)(2) with a PMePh(2) ligand. Carbon 72-78 surfactant protein C Homo sapiens 16-20 19552844-11 2009 Fasting insulin and HOMA-IR were negatively correlated with the fasting and postprandial HDL-C levels (all P < 0.05), and positively correlated with the fasting and postprandial TC/HDL-C levels (all P < 0.05). Carbon 92-94 insulin Homo sapiens 8-15 18848983-6 2009 Increased amounts of TNF-alpha and IL-6 were also evident in SDR DC cultures stimulated with poly(I:C). Carbon 99-101 interleukin 6 Mus musculus 35-39 18853239-7 2009 FT-IR/ATR results showed the distinct amino absorption bands presented at 3352 cm(-1)and 1613 cm(-1) after modification and XPS binding energies of C(1s) at 285.5 eV and N(1s) at 399.0 eV verified the existence of C-N bond formation on the PET film surface. Carbon 148-149 ATR serine/threonine kinase Homo sapiens 6-9 19243248-0 2009 Adenovirus-mediated wild-type p53 transfer radiosensitizes H1299 cells to subclinical-dose carbon-ion irradiation through the restoration of p53 function. Carbon 91-97 tumor protein p53 Homo sapiens 30-33 19243248-0 2009 Adenovirus-mediated wild-type p53 transfer radiosensitizes H1299 cells to subclinical-dose carbon-ion irradiation through the restoration of p53 function. Carbon 91-97 tumor protein p53 Homo sapiens 141-144 19201187-4 2009 In order to achieve elevated rates of nucleotide biosynthesis, neoplastic cells must divert carbon from PI3K/Akt-induced glycolytic flux into the nonoxidative branch of the pentose phosphate pathway to generate ribose-5-phosphate. Carbon 92-98 AKT serine/threonine kinase 1 Homo sapiens 109-112 18629679-3 2009 The affinity of these N-n-alkylnicotinium compounds was shown to parabolically vary with increasing numbers of carbon atoms in the n-alkyl chain, with a local minimum for the C(4) (n-butyl) analogue. Carbon 111-117 complement C4A Rattus norvegicus 175-179 19073345-9 2009 CONCLUSION: This study shows that CRP and neopterin have a role in differentiating bacterial from viral causes of ARTI, and the C/N ratio yields optimal differentiation in the ED setting. Carbon 0-1 C-reactive protein Homo sapiens 34-37 18550276-0 2009 Adsorption of Pb(II) and Pb(II)-citric acid on sawdust activated carbon: Kinetic and equilibrium isotherm studies. Carbon 65-71 submaxillary gland androgen regulated protein 3B Homo sapiens 14-20 19148501-7 2009 The proportion of Wnt1 positive women in group A (29.4%) was significantly higher than in group B (4.3%) and C (9.1%) (p=0.020). Carbon 109-110 Wnt family member 1 Homo sapiens 18-22 19148501-9 2009 The proportion of Wnt5a positive women was significantly higher for group A (80.0%) compared to group B (25.0%) and C (27.3%) (p<0.001). Carbon 116-117 Wnt family member 5A Homo sapiens 18-23 19441470-8 2009 Pin-on-disk wear analyses demonstrate a prolonged wear life of TiN coatings by Preimplantation of Ti2+ and C+ ions. Carbon 107-109 dynein light chain LC8-type 1 Homo sapiens 0-3 18550276-0 2009 Adsorption of Pb(II) and Pb(II)-citric acid on sawdust activated carbon: Kinetic and equilibrium isotherm studies. Carbon 65-71 submaxillary gland androgen regulated protein 3B Homo sapiens 25-31 18550276-1 2009 The removal of Pb(II) and Pb(II)-citric acid (Pb(II)-CA) from aqueous solutions by sawdust activated carbon (SDAC) was investigated. Carbon 101-107 submaxillary gland androgen regulated protein 3B Homo sapiens 15-21 19257434-0 2009 Nonlinear impact of edge localized modes on carbon erosion in the divertor of the JET tokamak. Carbon 44-50 F-box and leucine rich repeat protein 15 Homo sapiens 82-85 18550276-1 2009 The removal of Pb(II) and Pb(II)-citric acid (Pb(II)-CA) from aqueous solutions by sawdust activated carbon (SDAC) was investigated. Carbon 101-107 submaxillary gland androgen regulated protein 3B Homo sapiens 26-32 18550276-1 2009 The removal of Pb(II) and Pb(II)-citric acid (Pb(II)-CA) from aqueous solutions by sawdust activated carbon (SDAC) was investigated. Carbon 101-107 submaxillary gland androgen regulated protein 3B Homo sapiens 26-32 19257434-1 2009 The impact of edge localized modes (ELMs) carrying energies of up to 450 kJ on carbon erosion in the JET inner divertor is assessed by means of time resolved measurements using an in situ quartz microbalance diagnostic. Carbon 79-85 F-box and leucine rich repeat protein 15 Homo sapiens 101-104 19154603-0 2009 Effective carbon partitioning driven by exotic phloem-specific regulatory elements fused to the Arabidopsis thaliana AtSUC2 sucrose-proton symporter gene. Carbon 10-16 sucrose-proton symporter 2 Arabidopsis thaliana 117-123 19122898-1 2009 Unexpected formation of the novel dianionic N,C-chelate ligand LD2- [HC[C(Me)-NR][C(NHR)=CH]]2- occurs by a twice silicon-assisted C-H bond activation of a terminal methyl group on a beta-diketiminato ligand backbone, starting from the corresponding lithium beta-diketiminide and silicon tetrabromide to give the new N-heterocyclic dibromosilanes and . Carbon 46-47 amyloid beta precursor protein Homo sapiens 181-187 19154603-6 2009 CoYMVp::AtSUC2 cDNA restored growth and carbon partitioning to near wild-type levels, whereas plants harboring rolCp::AtSUC2 cDNA showed only partial complementation. Carbon 40-46 sucrose-proton symporter 2 Arabidopsis thaliana 8-14 18462869-9 2009 The adsorption capacity for Pb(II), Cd(II) and Cr(III) ions has been improved with respect to non-modified carbon reaching a maximum of 140%. Carbon 107-113 submaxillary gland androgen regulated protein 3B Homo sapiens 28-34 18462869-11 2009 The enhancement percent of Pb(II), Cd(II) and Cr(III) at different pH values was varied from 28% to 140% with respect to non-modified carbon. Carbon 134-140 submaxillary gland androgen regulated protein 3B Homo sapiens 27-33 18455868-0 2009 Ca10(PO4)6(OH)2-modified carbon-paste electrode for the determination of trace lead(II) by square-wave voltammetry. Carbon 25-31 carbonic anhydrase 10 Homo sapiens 0-4 21817222-5 2009 We have found that C(11), C(22) and C(33) elastic constants of hafnia and zirconia show increased strength with respect to the experimental values of the normal phase, P 2(1)/c. Carbon 19-20 cyclin dependent kinase inhibitor 1A Homo sapiens 168-174 18462869-0 2009 Tartrazine modified activated carbon for the removal of Pb(II), Cd(II) and Cr(III). Carbon 30-36 submaxillary gland androgen regulated protein 3B Homo sapiens 56-62 18462869-2 2009 The method was based on the modification of activated carbon with tartrazine then its application for the removal of Pb(II), Cd(II) and Cr(III) ions at different pH values. Carbon 54-60 submaxillary gland androgen regulated protein 3B Homo sapiens 117-123 19084625-4 2009 The determination of the carbon isotope composition of DIC was clearly useful for distinguishing between naturally and artificially sparkling waters. Carbon 25-31 solute carrier family 25 member 10 Homo sapiens 55-58 21817222-5 2009 We have found that C(11), C(22) and C(33) elastic constants of hafnia and zirconia show increased strength with respect to the experimental values of the normal phase, P 2(1)/c. Carbon 26-27 cyclin dependent kinase inhibitor 1A Homo sapiens 168-174 21817222-5 2009 We have found that C(11), C(22) and C(33) elastic constants of hafnia and zirconia show increased strength with respect to the experimental values of the normal phase, P 2(1)/c. Carbon 26-27 cyclin dependent kinase inhibitor 1A Homo sapiens 168-174 18848914-0 2009 Sensitive amperometric immunosensor for alpha-fetoprotein based on carbon nanotube/gold nanoparticle doped chitosan film. Carbon 67-73 alpha fetoprotein Homo sapiens 40-57 18848914-2 2009 The immunosensor was prepared by immobilizing AFP antigen onto the glassy carbon electrode (GC) modified by gold nanoparticles and carbon nanotubes doped chitosan (GNP/CNT/Ch) film. Carbon 74-80 alpha fetoprotein Homo sapiens 46-49 19035590-0 2009 Selective benzylic and allylic alkylation of protic nucleophiles with sulfonamides through double Lewis acid catalyzed cleavage of sp3 carbon-nitrogen bonds. Carbon 135-141 Sp3 transcription factor Homo sapiens 131-134 19014888-2 2009 Selective serotonin re-uptake inhibitors (SSRIs)(a) (i.e., (R)- and (S)-norfluoxetine) were chemically linked to a PDE4 inhibitor via a five carbon bridge. Carbon 141-147 phosphodiesterase 4A Homo sapiens 115-119 19266521-8 2009 Insertion of vinyl acetate into the Co-H bond of [Co(III)(H)(por)] also proceeds over a low barrier (DeltaG(double dagger) = +11.4 kcal mol(-1)) hydrogen-transfer step from [Co(III)(H)(por)] to a carbon atom of the alkene to produce a close-contact radical pair. Carbon 196-202 cytochrome p450 oxidoreductase Homo sapiens 61-64 19130438-0 2009 The copper-catalyzed decarboxylative coupling of the sp3-hybridized carbon atoms of alpha-amino acids. Carbon 68-74 Sp3 transcription factor Homo sapiens 53-56 18603423-1 2009 Using chromatography on nanostructured carbon sorbent we had isolated an unusual nanocomplex from filling grains of wheat and maize, which consists of only phosphatidylinositol (PI) and one protein-glutamate dehydrogenase (GDh). Carbon 39-45 glutamate dehydrogenase Zea mays 190-221 18603423-1 2009 Using chromatography on nanostructured carbon sorbent we had isolated an unusual nanocomplex from filling grains of wheat and maize, which consists of only phosphatidylinositol (PI) and one protein-glutamate dehydrogenase (GDh). Carbon 39-45 glutamate dehydrogenase Zea mays 223-226 18703329-0 2009 Hydrogen peroxide biosensor based on direct electrochemistry of soybean peroxidase immobilized on single-walled carbon nanohorn modified electrode. Carbon 112-118 peroxidase Glycine max 72-82 19739147-4 2009 Graphene is an excellent electrode material with the advantages of conductivity and electrochemistry of sp2 carbon but without the disadvantages related to carbon nanotubes, such as residual metallic impurities. Carbon 108-114 Sp2 transcription factor Homo sapiens 104-107 19739148-5 2009 The Lewis acid mediated/catalyzed additions and substitutions, to form sp3-carbon-phosphorus bonds including an asymmetric reaction, are described. Carbon 75-81 Sp3 transcription factor Homo sapiens 71-74 20216936-3 2009 Currently available carbon-11 SERT PET tracers come from both the diphenylsulfide and 3beta-phenyl nortropane class, but so far only the nortropanes have found success with fluorine-18 derivatives. Carbon 20-26 solute carrier family 6 member 4 Homo sapiens 30-34 19634432-0 2009 Kinetic adsorption of application of carbon nanotubes for Pb(II) removal from aqueous solution. Carbon 37-43 submaxillary gland androgen regulated protein 3B Homo sapiens 58-64 18607531-3 2009 In terms of structural specificity, the methoxyl group on C-5 and C-7 and the short alkyl chain (1-5 carbons) on C-6 may be essential for the potent activities. Carbon 101-108 hemolytic complement Mus musculus 58-61 19936111-12 2009 These findings suggested that CYP 3 is a good source of carbon and energy, and may improve bacterial community diversity and modulate short-chain fatty acid production in hindgut of rats. Carbon 56-62 cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus 30-35 22408512-5 2009 In such sensors, the enzyme AChE has been immobilized onto nanomaterials like multiwalled carbon nanotubes, gold nanoparticles, zirconia nanoparticles, cadmium sulphide nano particles or quantum dots. Carbon 90-96 acetylcholinesterase (Cartwright blood group) Homo sapiens 28-32 19356132-1 2009 Novel affinity biosensors for detecting cellular prions, PrP(C), based on DNA aptamers and antibodies immobilized onto the carbon nanotubes have been designed and compared in accordance with their binding ability and analytical performance. Carbon 123-129 prion protein Homo sapiens 57-63 19075224-4 2008 In Borneo, carbon emissions from fires were highly variable, fluxes during the moderate 2006 El Nino more than 30 times greater than those during the 2000 La Nina (and with a 2000-2006 mean of 74 +/- 33 Tg C yr(-1)). Carbon 11-17 transglutaminase 2 Homo sapiens 203-207 19074288-6 2008 Under this condition, 9"- or 13"-carboxychromanol, the vitamin E metabolites that contain a chromanol linked with a 9- or 13-carbon-length carboxylated side chain, inhibits COX-2 with an IC(50) of 6 or 4 microM, respectively. Carbon 125-131 mitochondrially encoded cytochrome c oxidase II Homo sapiens 173-178 19012397-4 2008 The structure of the isolated SPTpT dinucleotide was revisited in order to determine the type of cross-link and the absolute configuration of the C5a carbon. Carbon 150-156 complement C5a receptor 1 Homo sapiens 146-149 18722103-1 2008 Carbonized TiO(2) nanotubes (TNT/C) prepared by carbonization with organic polymers possess advantages combined from high conductivity of carbon and nanostructure of TiO(2) nanotubes. Carbon 48-54 chromosome 16 open reading frame 82 Homo sapiens 29-32 19113739-1 2008 Semiconducting single-wall carbon nanotubes under high electric field stress ( approximately 10 V/mum) display a remarkable current increase due to avalanche generation of free electrons and holes. Carbon 27-33 latexin Homo sapiens 98-101 18998731-1 2008 DFT calculations support a concerted mechanism for xanthine oxidase and aldehyde oxidase hydride displacement from the sp(2) carbon of 6-substituted 4-quinazolinones. Carbon 125-131 aldehyde oxidase 1 Homo sapiens 72-88 18692385-1 2008 The electrochemical behavior of insulin at glassy carbon (GC) electrode modified with nickel oxide nanoparticles and guanine was investigated. Carbon 50-56 insulin Homo sapiens 32-39 18647136-7 2008 The rate constant of this reaction would be directly related to the strength of the nucleophilic attack of the C-1 hydroxyl group, which depends on the chemical shift of the carbon C-1 (delta(1)) obtained by (13)C-NMR. Carbon 174-180 delta like non-canonical Notch ligand 1 Homo sapiens 181-194 18647136-7 2008 The rate constant of this reaction would be directly related to the strength of the nucleophilic attack of the C-1 hydroxyl group, which depends on the chemical shift of the carbon C-1 (delta(1)) obtained by (13)C-NMR. Carbon 111-112 delta like non-canonical Notch ligand 1 Homo sapiens 181-194 18722103-4 2008 The TNT/C-Hb modified glassy carbon electrode (GCE) demonstrates significant electrocatalytic activity for reduction of hydrogen peroxide with a small apparent Michaelis-Menten constant (87.5 microM). Carbon 29-35 chromosome 16 open reading frame 82 Homo sapiens 4-7 19019152-4 2008 Previous reports show that PIS1 expression is uncoupled from inositol/choline regulation, but is regulated by carbon source, hypoxia and zinc. Carbon 110-116 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 27-31 19043251-4 2008 Our results suggest that the antioxidant activity or electrophilic nature of the C-8 carbon, both of which are afforded by the C-8/C-9 double bond, may play a role in the cytoprotective properties of this alkaloid. Carbon 85-91 complement C9 Rattus norvegicus 127-134 18989861-1 2008 The polarization dependence (linear dichroism) of the C 1s X-ray absorption spectrum of individual multi-walled carbon nanotubes (MWCNTs) is measured using scanning transmission X-ray microscopy. Carbon 112-118 complement C1s Homo sapiens 54-58 18682385-6 2008 Consistent with the function of Oac1p as an alpha-IPM transporter, cells lacking the gene for this carrier required leucine for optimal growth on fermentable carbon sources. Carbon 158-164 Oac1p Saccharomyces cerevisiae S288C 32-37 18721997-2 2008 The mechanism involves a chain reaction with both homolytic photochemical C-Cl bond fission and electron transfer steps producing PCB anion radicals. Carbon 74-75 pyruvate carboxylase Homo sapiens 130-133 18678883-1 2008 The disproportionate micromelia (Dmm) mouse has a mutation in the C-propeptide coding region of the Col2a1 gene that causes lethal dwarfism when homozygous (Dmm/Dmm) but causes only mild dwarfism observable approximately 1-week postpartum when heterozygous (Dmm/+). Carbon 66-68 collagen, type II, alpha 1 Mus musculus 100-106 18336939-5 2008 Carbon ions (108keV/microm) decreased the difference in the apoptotic incidence between Bcl-2 and Neo cells, and prolonged G(2)/M arrest that occurred more extensively in Bcl-2 cells than in Neo cells. Carbon 0-6 BCL2 apoptosis regulator Homo sapiens 88-93 18336939-5 2008 Carbon ions (108keV/microm) decreased the difference in the apoptotic incidence between Bcl-2 and Neo cells, and prolonged G(2)/M arrest that occurred more extensively in Bcl-2 cells than in Neo cells. Carbon 0-6 BCL2 apoptosis regulator Homo sapiens 171-176 21836238-0 2008 Anthocyanin-sensitized solar cells using carbon nanotube films as counter electrodes. Carbon 41-47 DDB1 and CUL4 associated factor 7 Homo sapiens 0-11 21836238-1 2008 Carbon nanotube (CNT) films have been used as counter electrodes in natural dye-sensitized (anthocyanin-sensitized) solar cells to improve the cell performance. Carbon 0-6 DDB1 and CUL4 associated factor 7 Homo sapiens 92-103 19047824-2 2008 Deletion of the tpi1 (triosephosphate isomerase) gene in S. cerevisiae increased the carbon flux to DHAP (dihydroxylacetone phosphate) in glycolysis, resulting in increased glycerol production. Carbon 85-91 triose-phosphate isomerase TPI1 Saccharomyces cerevisiae S288C 16-20 18682385-9 2008 Oac1p is important for leucine biosynthesis on fermentable carbon sources catalyzing the export of alpha-IPM, probably in exchange for oxalacetate. Carbon 59-65 Oac1p Saccharomyces cerevisiae S288C 0-5 18670728-3 2008 The organic carbon normalized soil sorption coefficient (K(oc)) was calculated to be 94-96 mL/g at 1 h after the application. Carbon 12-18 solute carrier family 6 member 1 Homo sapiens 94-100 18804623-0 2008 Alumina sol-gel/sonogel-carbon electrode based on acetylcholinesterase for detection of organophosphorus pesticides. Carbon 24-30 acetylcholinesterase (Cartwright blood group) Homo sapiens 50-70 18804623-1 2008 Two new amperometric biosensors based on immobilization of acetylcholinesterase on a sonogel-carbon electrode for detection of organophosphorous compounds are proposed. Carbon 93-99 acetylcholinesterase (Cartwright blood group) Homo sapiens 59-79 18804623-3 2008 The first biosensor was obtained by simple entrapping acetylcholinesterase in Al(2)O(3) sol-gel matrix on the sonogel-carbon. Carbon 118-124 acetylcholinesterase (Cartwright blood group) Homo sapiens 54-74 18799315-2 2008 MAO-B catalyzes the ring alpha-carbon 2-electron bioactivation of MPTP to yield the 1-methyl-4-phenyl-2,3-dihydropyridinium species (MPDP(+)). Carbon 31-37 monoamine oxidase B Bos taurus 0-5 18799315-7 2008 We conclude that the mechanism of the MAO-B-catalyzed oxidation of pyrrolinyl substrates is similar to that of the tetrahydropyridinyl substrates and that a carbon-hydrogen bond cleavage step is, at least partially, rate determining. Carbon 157-163 monoamine oxidase B Bos taurus 38-43 18816038-0 2008 Determining the transition-state structure for different SN2 reactions using experimental nucleophile carbon and secondary alpha-deuterium kinetic isotope effects and theory. Carbon 102-108 solute carrier family 38 member 5 Homo sapiens 57-60 18617259-0 2008 Induced stepwise conformational change of human serum albumin on carbon nanotube surfaces. Carbon 65-71 albumin Homo sapiens 48-61 18617259-2 2008 In this study, the adsorption dynamics and features of a model protein (the A sub-domain of human serum albumin) onto the surfaces of carbon nanotubes with different diameters were investigated out by molecular dynamics simulation. Carbon 134-140 albumin Homo sapiens 98-111 19123362-5 2008 The results showed that the application of synthetic nitrogen fertilizer could bring about a carbon sequestration potential of 21.9 Tg C x a(-1) in current situation, and 30.2 Tg C x a(-1) with fertilization as recommended. Carbon 93-99 transglutaminase 2 Homo sapiens 132-136 19123362-6 2008 However, under the two scenarios, the greenhouse gas leakage caused by fertilizer production and application would reach 72.9 Tg C x a(-1) and 91.4 Tg C x a(-1), and thus, the actual available carbon sequestration potential would be -51.0 Tg C x a(-1) and -61.1 Tg C x a(-1), respectively. Carbon 193-199 transglutaminase 2 Homo sapiens 126-130 19123362-6 2008 However, under the two scenarios, the greenhouse gas leakage caused by fertilizer production and application would reach 72.9 Tg C x a(-1) and 91.4 Tg C x a(-1), and thus, the actual available carbon sequestration potential would be -51.0 Tg C x a(-1) and -61.1 Tg C x a(-1), respectively. Carbon 193-199 transglutaminase 2 Homo sapiens 148-152 19123362-6 2008 However, under the two scenarios, the greenhouse gas leakage caused by fertilizer production and application would reach 72.9 Tg C x a(-1) and 91.4 Tg C x a(-1), and thus, the actual available carbon sequestration potential would be -51.0 Tg C x a(-1) and -61.1 Tg C x a(-1), respectively. Carbon 193-199 transglutaminase 2 Homo sapiens 148-152 19123362-6 2008 However, under the two scenarios, the greenhouse gas leakage caused by fertilizer production and application would reach 72.9 Tg C x a(-1) and 91.4 Tg C x a(-1), and thus, the actual available carbon sequestration potential would be -51.0 Tg C x a(-1) and -61.1 Tg C x a(-1), respectively. Carbon 193-199 transglutaminase 2 Homo sapiens 148-152 18702630-2 2008 In this research, chicken cystatin, a model protein inhibitor of cysteine proteinases, was acylated with fatty acyl residues of 6-18 carbon atoms. Carbon 133-139 cystatin C Gallus gallus 26-34 18766222-1 2008 An unique long-range 1,7-bromination reaction is observed in gold(III) complexes of N-(aryl)imino functionalized N-heterocyclic carbene with the bromination occurring at two different carbon (sp2 and sp3) centers spatially separated by ca. Carbon 184-190 Sp2 transcription factor Homo sapiens 192-195 18766222-1 2008 An unique long-range 1,7-bromination reaction is observed in gold(III) complexes of N-(aryl)imino functionalized N-heterocyclic carbene with the bromination occurring at two different carbon (sp2 and sp3) centers spatially separated by ca. Carbon 184-190 Sp3 transcription factor Homo sapiens 200-203 18606812-6 2008 The pfkA2 deletion strain had an increased carbon flux through the pentose phosphate pathway, as measured by (13)C metabolic flux analysis, establishing the ATP-dependent PfkA2 as a key player in determining the carbon flux distribution. Carbon 43-49 SCO5426 Streptomyces coelicolor A3(2) 4-9 18606812-6 2008 The pfkA2 deletion strain had an increased carbon flux through the pentose phosphate pathway, as measured by (13)C metabolic flux analysis, establishing the ATP-dependent PfkA2 as a key player in determining the carbon flux distribution. Carbon 43-49 SCO5426 Streptomyces coelicolor A3(2) 171-176 18606812-6 2008 The pfkA2 deletion strain had an increased carbon flux through the pentose phosphate pathway, as measured by (13)C metabolic flux analysis, establishing the ATP-dependent PfkA2 as a key player in determining the carbon flux distribution. Carbon 212-218 SCO5426 Streptomyces coelicolor A3(2) 4-9 18606812-6 2008 The pfkA2 deletion strain had an increased carbon flux through the pentose phosphate pathway, as measured by (13)C metabolic flux analysis, establishing the ATP-dependent PfkA2 as a key player in determining the carbon flux distribution. Carbon 212-218 SCO5426 Streptomyces coelicolor A3(2) 171-176 18707103-3 2008 In the work described in this paper, density functional theory calculations have been used to evaluate the effectiveness of different ML3 complexes to activate the C-S bonds in CS2 and CS, with M = Mo, Re, W, and Ta and L = NH2. Carbon 164-165 chorionic somatomammotropin hormone 2 Homo sapiens 177-180 18707103-4 2008 These calculations show that the combination of Re and Ta in the L3Re/CS2/TaL3 complex would be the most promising system for the cleavage of both C-S bonds of CS2. Carbon 70-71 chorionic somatomammotropin hormone 2 Homo sapiens 160-163 18758024-1 2008 (2SR,4RS)-7-Chloro-2-exo-[(E)-styryl]-2,3,4,5-tetrahydro-1H-1,4-epoxy-1-benzazepine, C(18)H(16)ClNO, (I), crystallizes as a racemic twin in the space group P2(1) and the molecules are linked into a chain of edge-fused R(3)(3)(9) rings by a combination of C-H...O and C-H...N hydrogen bonds. Carbon 12-13 cyclin dependent kinase inhibitor 1A Homo sapiens 156-161 18023577-1 2008 In this study, the kinetics of adsorption of Pb(II) from aqueous solution onto palm shell-based activated carbon (PSAC) were investigated by employing ion selective electrode (ISE) for real-time Pb(II) and pH monitoring. Carbon 106-112 submaxillary gland androgen regulated protein 3B Homo sapiens 45-51 18800170-7 2008 The LCB of the main ganglioside species has either 18 or 20 carbons (i.e., C18- or C20-sphingosine); we found that these 2 types of gangliosides are differentially distributed in the mouse brain. Carbon 60-67 clathrin, light polypeptide (Lcb) Mus musculus 4-7 18781025-1 2008 The present paper reports on the application of modified multiwalled carbon nanotubes (MMWCNTs) as a new, easily prepared and stable solid sorbent for the preconcentration of trace Co(II) in aqueous solution. Carbon 69-75 mitochondrially encoded cytochrome c oxidase II Homo sapiens 181-187 18794599-0 2008 High-efficiency transfer and expression of AdCMV-p53 in human hepatocellular carcinoma cells induced by low-dose carbon-ion radiation. Carbon 113-119 tumor protein p53 Homo sapiens 49-52 18795165-0 2008 Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells. Carbon 16-22 nuclear factor kappa B subunit 1 Homo sapiens 83-92 18795165-0 2008 Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells. Carbon 16-22 AKT serine/threonine kinase 1 Homo sapiens 98-101 18650401-6 2008 Expression of AtSUC2 cDNA from the 2-kb AtSUC2 promoter was sufficient to restore growth and carbon partitioning to nearly wild-type levels. Carbon 93-99 sucrose-proton symporter 2 Arabidopsis thaliana 14-20 18650401-6 2008 Expression of AtSUC2 cDNA from the 2-kb AtSUC2 promoter was sufficient to restore growth and carbon partitioning to nearly wild-type levels. Carbon 93-99 sucrose-proton symporter 2 Arabidopsis thaliana 40-46 18410483-2 2008 Sugar-induced ABI4 regulates plant genes essential for photosynthesis, and carbon, nitrogen and lipid metabolism. Carbon 75-81 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 14-18 18249492-0 2008 Column performance of granular activated carbon packed bed for Pb(II) removal. Carbon 41-47 submaxillary gland androgen regulated protein 3B Homo sapiens 63-69 18249492-3 2008 In this paper an attempt has been made to investigate the adsorption behaviour of Pb(II) from aqueous systems onto granular activated carbon using the batch mode and continuous mode in a packed bed column with more successive service and regeneration. Carbon 134-140 submaxillary gland androgen regulated protein 3B Homo sapiens 82-88 18767670-6 2008 Pore water concentrations decreased up to 60% within 18 months after activated carbon amendment, as compared to a mechanical-mixed control plot Results of this study illustrate PEDs provide an inexpensive, in situ method to measure total PCB contamination in sediment pore water using a small set of PRCs. Carbon 79-85 pyruvate carboxylase Homo sapiens 238-241 18978171-1 2008 OBJECTIVE: Vitamin E and C given separately improve insulin sensitivity due to an inhibitory effect on oxidative stress and inflammation, however their combined effect on glucose control and inflammation is unknown. Carbon 4-5 insulin Homo sapiens 52-59 18978171-2 2008 To investigate combined effect of Vitamin E and C in elderly with Impaired Fasting Glucose (IFG) on insulin action and substrate oxidation. Carbon 48-49 insulin Homo sapiens 100-107 19049221-1 2008 Our previous work revealed that significant enhancement in sp3-carbon content of amorphous carbon films could be achieved when grown on nanocrystalline palladium interlayer as compared to those grown on bare silicon substrates. Carbon 63-69 Sp3 transcription factor Homo sapiens 59-62 19049221-1 2008 Our previous work revealed that significant enhancement in sp3-carbon content of amorphous carbon films could be achieved when grown on nanocrystalline palladium interlayer as compared to those grown on bare silicon substrates. Carbon 91-97 Sp3 transcription factor Homo sapiens 59-62 18282165-9 2008 We conclude that carbon-ion irradiation induced cell death and senescence in a glioblastoma cell line with mutant TP53. Carbon 17-23 tumor protein p53 Homo sapiens 114-118 18975736-3 2008 The carbon density and stock in different artificial forest ecosystems varied from 75.50 Mg C x hm(-2) to 251.74 Mg C x hm(-2) and from 1.21 Tg C to 99.44 Tg C, with the highest and lowest values observed in soil layer and shrub layer, respectively. Carbon 4-10 transglutaminase 2 Homo sapiens 141-145 18597451-3 2008 Strong linear dependences are found between the computed electrostatic potential at the reaction-center carbon atom and the effective SN2 activation energies within the series of para-substituted benzyl fluorides. Carbon 104-110 solute carrier family 38 member 5 Homo sapiens 134-137 18507437-2 2008 The radical is formed by a net glycosidic bond cleavage, giving rise to a glucose-centered radical with the major part of the spin density residing at the C 1 carbon atom. Carbon 159-165 T cell receptor gamma constant 1 Homo sapiens 155-158 18585301-4 2008 Among the products, L-ascorbic acid showed the most sensitive (24.8 microA cm(-2), 12.0 microA cm(-2), and 48.0 microA cm(-2) of 100 microM ascorbic acid at GC, SPC, and Au electrodes, respectively) and well-defined amperometric response at all electrodes used, making 2-phospho-l-ascorbic acid the best substrate in electrochemical detection involving an alkaline phosphatase (ALP) enzyme label. Carbon 157-159 alkaline phosphatase, placental Homo sapiens 356-376 18585301-4 2008 Among the products, L-ascorbic acid showed the most sensitive (24.8 microA cm(-2), 12.0 microA cm(-2), and 48.0 microA cm(-2) of 100 microM ascorbic acid at GC, SPC, and Au electrodes, respectively) and well-defined amperometric response at all electrodes used, making 2-phospho-l-ascorbic acid the best substrate in electrochemical detection involving an alkaline phosphatase (ALP) enzyme label. Carbon 157-159 alkaline phosphatase, placental Homo sapiens 378-381 18844165-9 2008 The IR spectrum absorbance bands of bovine serum albumin and BPA appeared on the IR spectrum graph of artificial antigen of BPA, moreover, shrinked vibration bands at 1 000-1 300 cm(-1) showed that a C-N bond was produced and suggested that the modified BPA and BSA had been linked. Carbon 200-201 albumin Homo sapiens 43-56 20641586-8 2004 [(11)C]N,N-Dimethyl-2-(2-amino-4-cyanophenylthio)benzylamine ([(11)C]DASB) was found to be a promising tracer for SERT imaging in animals and humans (6-9). Carbon 5-6 solute carrier family 6 member 4 Homo sapiens 114-118 18612512-1 2008 A long, two-electron ten-center (2e(-)/10c) [8 carbon plus 2 oxygen] bond in diamagnetic dimers of radical-anion tetracyano-1,4-benzoquinoneide (cyanil, [Q] (-)), [Q](2)(2-), is described by B3LYP and CASSCF(2,2)/MCQDPT calculations. Carbon 47-53 Rho GTPase activating protein 9 Homo sapiens 39-42 18599981-1 2008 Molecules of the title compound, C(12)H(13)ClN(4), are linked by two independent N-H...N hydrogen bonds into a chain of edge-fused R(2)(2)(8) rings. Carbon 33-34 DnaJ heat shock protein family (Hsp40) member C5 Homo sapiens 43-48 18528299-5 2008 Meanwhile, results of in vitro culture assay showed that poly I:C synergized with B16 cells could significantly promote IKDCs expansion in lymphocytes from different organs along with IFN-gamma production. Carbon 64-65 interferon gamma Mus musculus 184-193 18673151-6 2008 We here show that the kinetics of aspartate formation during the first 30 min (0.36 +/- 0.03 micromol g(-1) min(-1)) are altered such that glutamate, via aspartate aminotransferase, becomes the primary source of carbon when glucose-derived pyruvate is unavailable. Carbon 212-218 glutamic-oxaloacetic transaminase 2 Rattus norvegicus 154-180 18507437-3 2008 A concerted formation of a carbonyl group at the C 2 carbon accounts for the relatively small spin density at C 1 and the enhanced g factor anisotropy of the radical, both well-known properties of this radical from several previous experimental investigations. Carbon 27-33 T cell receptor gamma constant 1 Homo sapiens 110-113 18053642-0 2008 Removal of Pb(II) from aqueous solution by oxidized multiwalled carbon nanotubes. Carbon 64-70 submaxillary gland androgen regulated protein 3B Homo sapiens 11-17 18286553-0 2008 Targeted RNA interference of cyclin A2 mediated by functionalized single-walled carbon nanotubes induces proliferation arrest and apoptosis in chronic myelogenous leukemia K562 cells. Carbon 80-86 cyclin A2 Homo sapiens 29-38 18447326-3 2008 Because the bip moiety (R, R or S, S configuration at the 2,2"-carbon atoms) does not have planes of symmetry, the requirements of the crystal symmetry are satisfied by a statistical disorder made of bip molecules of R, R or S, S configurations alternating at the same crystallographic site. Carbon 63-69 heat shock protein family A (Hsp70) member 5 Homo sapiens 12-15 18493684-1 2008 High selectivity and sensitivity is reported in the measurements of xanthine in urine by fast scan cyclic voltammetry (FSV) with a nanostructured carbon fiber sensor of 3.5 +/- 0.4 mum radius. Carbon 146-152 latexin Homo sapiens 181-184 18609788-0 2008 Trusts face green targets in bid to cut carbon footprint. Carbon 40-46 BH3 interacting domain death agonist Homo sapiens 29-32 18374965-6 2008 However, p-nitrophenyl ester of (14)C-palmitic acid specifically labeled bovine ALB, indicating that the micro-environment of the fatty acid-binding domains of DBP and ALB may be different; and DBP may not replace ALB as a transporter of fatty acids. Carbon 36-37 D-box binding PAR bZIP transcription factor Bos taurus 160-163 18286553-7 2008 siRNA against cyclin A(2) delivered by functionalized single wall carbon nanotubes may be a useful therapeutic strategy for chronic myelogenous leukemia cells. Carbon 66-72 cyclin A2 Homo sapiens 14-24 18763486-5 2008 The seawater changes from carbon source to carbon sink of atmospheric CO2 with NO3- addition increased. Carbon 26-32 NBL1, DAN family BMP antagonist Homo sapiens 79-82 18560524-7 2008 Chemical analysis of CAPs identified low levels of elemental carbon. Carbon 61-67 calcyphosine Homo sapiens 21-25 18763486-5 2008 The seawater changes from carbon source to carbon sink of atmospheric CO2 with NO3- addition increased. Carbon 43-49 NBL1, DAN family BMP antagonist Homo sapiens 79-82 21202483-1 2008 In the crystal structure of the title compound, [Co(C(2)H(4)NO(2))(C(9)H(6)NO)(2)] CH(3)OH, the Co(III) atom is chelated by two quinolin-8-olate and one glycinate anions in a distorted octa-hedral coordination geometry. Carbon 49-50 mitochondrially encoded cytochrome c oxidase III Homo sapiens 96-103 18463533-6 2008 Up-regulation of genes encoding the T-cell-attracting chemokines CXCL9, 10, and 11 in poly(I:C)-DC but not PGE2-DC was confirmed on a protein level. Carbon 93-95 C-X-C motif chemokine ligand 9 Homo sapiens 65-70 18518310-1 2008 We demonstrate that when, and only when, the biaxial stress is increased above a critical value of 6+/-1 GPa during the growth of a carbon film at room temperature, tetrahedral amorphous carbon is formed. Carbon 132-138 glycophorin A (MNS blood group) Homo sapiens 105-108 18518310-1 2008 We demonstrate that when, and only when, the biaxial stress is increased above a critical value of 6+/-1 GPa during the growth of a carbon film at room temperature, tetrahedral amorphous carbon is formed. Carbon 187-193 glycophorin A (MNS blood group) Homo sapiens 105-108 18469463-1 2008 A sequential injection-square-wave anodic stripping voltammetry (SIA-SWASV) is proposed for the simultaneous determination of Pb(II), Cd(II) and Zn(II), employing an in situ plated bismuth film screen-printed carbon electrode (Bi-SPCE) as a working electrode and hydrochloric acid as a supporting electrolyte. Carbon 209-215 submaxillary gland androgen regulated protein 3B Homo sapiens 126-132 17669408-9 2008 Treatment of FTEC with TLR3 agonist poly(I:C) resulted in increased expression of interleukin-8, tumor-necrosis factor alpha, human beta-defensin 2, interferon beta, and interferon stimulated genes myxovirus resistance gene 1, 2",5"-oligoadenylate synthetase, and protein kinase R. Additionally, FTEC exposed to poly(I:C) also resulted in the induction of TLR2, TLR3, and TLR7. Carbon 16-17 toll like receptor 7 Homo sapiens 372-376 18348549-3 2008 Our measurements indicate that the vapor pressures of the solid even-numbered alkanoic acids decrease monotonically with increasing carbon number by more than 6 orders of magnitude going from C8 to C18. Carbon 132-138 Bardet-Biedl syndrome 9 Homo sapiens 198-201 18092327-9 2008 In conclusion, these results suggest that increasing levels of plasma vitamin B12, alone or together with other factors involved in one-carbon metabolism, may reduce the risk of rectal cancer, whereas for colon cancer, the association appears to be less clear. Carbon 136-142 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 78-81 17669408-9 2008 Treatment of FTEC with TLR3 agonist poly(I:C) resulted in increased expression of interleukin-8, tumor-necrosis factor alpha, human beta-defensin 2, interferon beta, and interferon stimulated genes myxovirus resistance gene 1, 2",5"-oligoadenylate synthetase, and protein kinase R. Additionally, FTEC exposed to poly(I:C) also resulted in the induction of TLR2, TLR3, and TLR7. Carbon 16-17 C-X-C motif chemokine ligand 8 Homo sapiens 82-124 17669408-9 2008 Treatment of FTEC with TLR3 agonist poly(I:C) resulted in increased expression of interleukin-8, tumor-necrosis factor alpha, human beta-defensin 2, interferon beta, and interferon stimulated genes myxovirus resistance gene 1, 2",5"-oligoadenylate synthetase, and protein kinase R. Additionally, FTEC exposed to poly(I:C) also resulted in the induction of TLR2, TLR3, and TLR7. Carbon 16-17 toll like receptor 2 Homo sapiens 356-360 18292294-2 2008 To define the requirements for activation of the OXE receptor, we have synthesized a series of 5-oxo-6E,8Z-dienoic acids with chain lengths between 12 and 20 carbons, as well as a series of 20-carbon 5-oxo fatty acids, either fully saturated or containing between one and five double bonds. Carbon 158-165 oxoeicosanoid receptor 1 Homo sapiens 49-61 18221358-4 2008 Collagen (1 mug mL(-1))-induced platelet activation ((14)C-5HT release) and recruitment (proaggregatory activity of cell-free releasates from activated platelets) were assessed in PRP, PRP + RBC, and whole blood (WB). Carbon 0-1 prion protein Homo sapiens 180-183 18341332-1 2008 Insertion of an electron-deficient alkyne A-C[triple bond]C-A (A = CO2Me) into the C-L+ bond of an acyl-onio salt R-C(O)-L+ (R = Ar, OAlk; L = 4-dimethylaminopyridine, PPh3) has for the first time been achieved in the presence of catalytic amounts of the nucleophile L. For R = OMe, a second insertion of the alkyne was observed. Carbon 44-45 caveolin 1 Homo sapiens 168-172 18331798-0 2008 Tumor necrosis factor alpha mediates the lethal hepatotoxic effects of poly(I:C) in D-galactosamine-sensitized mice. Carbon 78-79 tumor necrosis factor Mus musculus 0-27 18312311-5 2008 New Indian evidence suggests that insulin resistance at birth seems linked to low birth weight and a higher proportion of body fat with selective B12 deficiency and abnormalities of one carbon pool metabolism potentially responsible and affecting 75% of Indians and many populations in the developing world. Carbon 186-192 insulin Homo sapiens 34-41 17728011-8 2008 L. japonicus nodule carbon metabolism proved to be less sensitive to salinity than in M. truncatula, as enzymatic activities responsible for the carbon supply to the bacteroids to fuel nitrogen fixation, such as sucrose synthase (SS), alkaline invertase (AI), malate dehydrogenase (MDH) and phosphoenolpyruvate carboxylase (PEPC), were less affected by salt than the corresponding activities in barrel medics. Carbon 20-26 phosphoenolpyruvate carboxylase Medicago truncatula 291-322 17728011-8 2008 L. japonicus nodule carbon metabolism proved to be less sensitive to salinity than in M. truncatula, as enzymatic activities responsible for the carbon supply to the bacteroids to fuel nitrogen fixation, such as sucrose synthase (SS), alkaline invertase (AI), malate dehydrogenase (MDH) and phosphoenolpyruvate carboxylase (PEPC), were less affected by salt than the corresponding activities in barrel medics. Carbon 20-26 phosphoenolpyruvate carboxylase Medicago truncatula 324-328 18354790-1 2008 Covalent attachment of the enzymes glucose oxidase and catalase to carbon nanotubes enables the tandem catalytic conversion of glucose and H(2)O(2) formed to power autonomous movement of the nanotubes. Carbon 67-73 catalase Homo sapiens 55-63 18207234-3 2008 Removal of inflammatory cytokines TNF, IL-6, IL-1beta and IL-8 was assessed by filtering cytokine spiked human plasma through the walls of the carbon modules under pressure. Carbon 143-149 C-X-C motif chemokine ligand 8 Homo sapiens 58-62 18006287-1 2008 The cysteamine (CA) was bound onto surface of the pretreated glassy carbon electrode (GC) with cyclic voltammetry (CV). Carbon 68-74 S100 calcium binding protein A12 Homo sapiens 16-18 18006287-1 2008 The cysteamine (CA) was bound onto surface of the pretreated glassy carbon electrode (GC) with cyclic voltammetry (CV). Carbon 68-74 S100 calcium binding protein A12 Homo sapiens 86-88 18305209-2 2008 We showed previously that induction of the NRT2.1 NO(3)(-) transporter gene by sugars was dependent on carbon metabolism downstream hexokinase (HXK) in glycolysis. Carbon 103-109 hexokinase 1 Homo sapiens 132-142 18321077-2 2008 By using a combination of accurate first principles calculations on graphene fragments and statistical analysis, I show that both isotropic and dipolar hyperfine interactions in sp2 carbon nanostructures can be accurately described in terms of the local electron spin distribution and atomic structure. Carbon 182-188 Sp2 transcription factor Homo sapiens 178-181 18305209-2 2008 We showed previously that induction of the NRT2.1 NO(3)(-) transporter gene by sugars was dependent on carbon metabolism downstream hexokinase (HXK) in glycolysis. Carbon 103-109 hexokinase 1 Homo sapiens 144-147 18247631-2 2008 A cooperative effect of two different copper (I) species-CuI and CuTC-accounts for this new copper-catalyzed desulfurative carbon-carbon cross-coupling reaction. Carbon 123-129 cutC copper transporter Homo sapiens 65-69 18309400-1 2008 We present a novel and facile synthesis methodology for obtaining graphitic carbon structures from Fe(II) and Co(II) gluconates. Carbon 76-82 mitochondrially encoded cytochrome c oxidase II Homo sapiens 110-116 18281058-7 2008 They also provide direct structural evidence supporting co-evolution of the coordinate regulation by Ca(2+) of contraction and energy production in muscle through the sharing of a common structural motif in troponin I and the catalytic subunit of PhK for their respective interactions with the homologous Ca(2+)-binding proteins troponin C and CaM. Carbon 101-102 phosphorylase kinase regulatory subunit alpha 2 Homo sapiens 247-250 18229935-1 2008 Decarboxylative coupling of sp-sp2 carbons is possible by palladium catalyst. Carbon 35-42 Sp2 transcription factor Homo sapiens 31-34 18247631-2 2008 A cooperative effect of two different copper (I) species-CuI and CuTC-accounts for this new copper-catalyzed desulfurative carbon-carbon cross-coupling reaction. Carbon 130-136 cutC copper transporter Homo sapiens 65-69 18177920-4 2008 The observed differences in sorption between the two reference black carbons for PCB-35 may be ascribed to the different chemical characteristics of the black carbons. Carbon 69-76 pyruvate carboxylase Homo sapiens 81-84 18292868-6 2008 High resolution spectra of C1s, at these angles, showed an increased amount of aliphatic carbon when compared to the spectra at normal emission. Carbon 89-95 complement C1s Homo sapiens 27-30 18275039-5 2008 The maximal effect was achieved at a chain length of four and six carbons, respectively, leading to an activity induction by a factor of 36 for PPARalpha and 18 for PPARgamma, respectively. Carbon 66-73 peroxisome proliferator activated receptor gamma Homo sapiens 165-174 18177920-4 2008 The observed differences in sorption between the two reference black carbons for PCB-35 may be ascribed to the different chemical characteristics of the black carbons. Carbon 159-166 pyruvate carboxylase Homo sapiens 81-84 18177920-9 2008 The observed nF (i.e., Freundlich exponent) values for PCB indicated greater linearity of the isotherms for the natural sediment than for the reference black carbons. Carbon 158-165 pyruvate carboxylase Homo sapiens 55-58 18036603-6 2008 For SWCNT-TCF coated with 100 dipping times, an additional spray-coating dramatically decreased the sheet resistance from 1300 to 340 Omega/square, which is accompanied by slight reduction of the transmittance from 88 to 80%. Carbon 4-9 hepatocyte nuclear factor 4 alpha Homo sapiens 10-13 18082226-6 2008 Carbon- and neon-ion microbeam irradiation similarly caused almost twofold increments in the levels of serine 15-phosphorylated p53 proteins, irrespective of whether 0.00026, 0.0013 or 0.0066% of cells were targeted. Carbon 0-6 tumor protein p53 Homo sapiens 128-131 18785516-8 2008 Compared with that of the control group, dC2/DV [B:(17 +/-5)%/L, C: (13 +/-4)%/L] showed a decrease (t = -11.82, -16.75, all P < 0.01) and dC3/DV [B:(3.2 +/- 0.8)%/L, C:(4.1 +/-1.2)%/L] and SR23 [B:(17.2 +/- 3.5)%, C:(28.3 +/- 6.9)%] showed an increase (t = 2. Carbon 0-1 anon-17Cb Drosophila melanogaster 41-44 18243872-0 2008 A multiwalled carbon nanotube/dihydropyran composite film electrode for insulin detection in a microphysiometer chamber. Carbon 14-20 insulin Homo sapiens 72-79 18243872-1 2008 We have developed a multiwalled carbon nanotube/dihydropyran (MWCNT/DHP) composite sensor for the electrochemical detection of insulin in a microfluidic device. Carbon 32-38 dihydropyrimidinase Homo sapiens 68-71 18243872-1 2008 We have developed a multiwalled carbon nanotube/dihydropyran (MWCNT/DHP) composite sensor for the electrochemical detection of insulin in a microfluidic device. Carbon 32-38 insulin Homo sapiens 127-134 18496607-3 2008 The difference between the two lies in the insertion of the second oxygen atom, HMS directing this atom onto the benzylic carbon of the substrate while HPPD hydroxylates the aromatic C1 carbon. Carbon 122-128 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 152-156 18496607-3 2008 The difference between the two lies in the insertion of the second oxygen atom, HMS directing this atom onto the benzylic carbon of the substrate while HPPD hydroxylates the aromatic C1 carbon. Carbon 186-192 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 152-156 17698408-6 2008 Cyclic voltammograms show an irreversible reduction of Co(III) in DMF using Glassy Carbon Electrode, GCE, the redox peaks for the aniline complexes appear at -0.20 and 0.525V. Carbon 83-89 mitochondrially encoded cytochrome c oxidase III Homo sapiens 55-62 18251483-0 2008 Bronsted acid-catalyzed insertion of aryldiazoacetates to sp2 carbon-CHO bond: facile construction of chiral all-carbon quaternary center. Carbon 62-68 Sp2 transcription factor Homo sapiens 58-61 18251483-0 2008 Bronsted acid-catalyzed insertion of aryldiazoacetates to sp2 carbon-CHO bond: facile construction of chiral all-carbon quaternary center. Carbon 113-119 Sp2 transcription factor Homo sapiens 58-61 18287036-1 2008 Analysis of the x-ray crystal structure of mono-substituted acetylenic thienopyrimidine 6 complexed with the ErbB family enzyme ErbB-4 revealed a covalent bond between the terminal carbon of the acetylene moiety and the sulfhydryl group of Cys-803 at the solvent interface. Carbon 181-187 epidermal growth factor receptor Homo sapiens 109-113 18056705-11 2008 Taken together, our present findings suggest that AMPK-dependent transcriptional induction and phosphorylation of p53 at Ser-46 play a crucial role in the induction of apoptosis under carbon source depletion. Carbon 184-190 tumor protein p53 Homo sapiens 114-117 18163630-5 2008 Similar close C-N interactions are observed in the crystal structure of the more sterically demanding isocyanide adduct, [Ni(CNCy)(PCy2NBz2)2]2(BF4)2, 4. Carbon 14-15 forkhead box G1 Homo sapiens 144-152 18371833-0 2008 Electroanalytical properties of cytochrome c by direct electrochemistry on multi-walled carbon nanotubes incorporated with DNA biocomposite film. Carbon 88-94 cytochrome c, somatic Homo sapiens 32-44 18371833-1 2008 A novel conductive biocomposite film (MWCNTs-DNA-cyt c) which contains multi-walled carbon nanotubes (MWCNTs) along with the incorporation of DNA and cytochrome c (cyt c) has been synthesized on glassy carbon electrode (GCE), gold (Au), indium tin oxide (ITO) and screen printed carbon electrode (SPCE) by potentiostatic methods. Carbon 84-90 cytochrome c, somatic Homo sapiens 49-54 17560717-1 2008 Activated carbon loaded with xylenol orange in a mini-column was used for the highly selective separation and preconcentration of Pb(II) ions. Carbon 10-16 submaxillary gland androgen regulated protein 3B Homo sapiens 130-136 18189400-0 2008 Amine basicity (pKb) controls the analyte binding energy on single walled carbon nanotube electronic sensor arrays. Carbon 74-80 AKT serine/threonine kinase 1 Homo sapiens 16-19 18083769-0 2008 Carbon nanoparticle-induced lung epithelial cell proliferation is mediated by receptor-dependent Akt activation. Carbon 0-6 AKT serine/threonine kinase 1 Homo sapiens 97-100 18083769-3 2008 Here the activation of the protein kinase B (Akt) signaling cascade by carbon nanoparticles was investigated with regard to its relevance for proliferation. Carbon 71-77 AKT serine/threonine kinase 1 Homo sapiens 45-48 18083769-4 2008 Kinetics and dose-response experiments demonstrated that Akt is specifically activated by nanoparticulate carbon particles in rat alveolar type II epithelial cells as well as in human bronchial epithelial cells. Carbon 106-112 AKT serine/threonine kinase 1 Rattus norvegicus 57-60 18323113-2 2008 In addition to soot particles, nanoparticles of organic carbon (NOC) were measured in the emissions of these test vehicles in significant number and mass concentrations. Carbon 56-62 nocturnin Homo sapiens 64-67 17924136-8 2008 From these and other data we conclude that Tdy1 and Sxd1 function independently to promote carbon export from leaves. Carbon 91-97 tocopherol cyclase, chloroplastic Zea mays 52-56 18272968-2 2008 present a very strong correlation between mean lifetime net ecosystem production (NEP, defined as the net rate of carbon (C) accumulation in ecosystems) and wet nitrogen (N) deposition. Carbon 114-120 membrane metalloendopeptidase Homo sapiens 82-85 21201906-1 2008 In the title compound, C(18)H(16)N(2)O(3), a potential inhibitor of the cyclo-oxygenase-2 isoenzyme, the pyrazoline ring exists in a flattened envelope conformation with one C atom deviating by 0.463 A from the mean plane of the remaining four atoms. Carbon 23-24 prostaglandin-endoperoxide synthase 2 Homo sapiens 72-89 18179464-0 2008 SAR of carbon-linked, 2-substituted purines: synthesis and characterization of AP23451 as a novel bone-targeted inhibitor of Src tyrosine kinase with in vivo anti-resorptive activity. Carbon 7-13 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 125-128 17761210-1 2008 Sequestration of polychlorinated biphenyls (PCBs) by activated carbon (AC) has been proposed as a remediation strategy for PCB-contaminated sediments. Carbon 63-69 pyruvate carboxylase Homo sapiens 44-47 17761210-1 2008 Sequestration of polychlorinated biphenyls (PCBs) by activated carbon (AC) has been proposed as a remediation strategy for PCB-contaminated sediments. Carbon 71-73 pyruvate carboxylase Homo sapiens 44-47 17761210-2 2008 However, published PCB-AC adsorption isotherm data are sparse and, while sediment-derived dissolved organic matter (DOM) and biofilms are likely to be present in sediments, the impacts of these loadings have not been quantified. Carbon 23-25 pyruvate carboxylase Homo sapiens 19-22 18232887-3 2008 A generic bond-counting rule is established, which should apply to most carbon structures where sp2 and sp3 hybrids coexist: e.g., it provides a qualitative account of the step energy order without detailed calculation. Carbon 72-78 Sp2 transcription factor Homo sapiens 96-99 18232887-3 2008 A generic bond-counting rule is established, which should apply to most carbon structures where sp2 and sp3 hybrids coexist: e.g., it provides a qualitative account of the step energy order without detailed calculation. Carbon 72-78 Sp3 transcription factor Homo sapiens 104-107 20641301-14 2004 R-[(11)C]Rolipram is being developed as a PET agent for the non-invasive study of PDE4 in the brain in small animals. Carbon 7-8 phosphodiesterase 4A Homo sapiens 82-86 21201302-1 2008 In the title compound, [Fe(C(5)H(5))(C(6)H(16)P(2))(CO)](C(12)H(13)BOP), the Fe(II) ion adopts a three-legged piano-stool geometry, with Fe Cg = 1.721 (5)A (Cg = the centroid defined by the C atoms of the cyclo-penta-dienyl ring). Carbon 27-28 BOP Homo sapiens 67-70 18289091-5 2008 FAAH inhibitors can be divided in two major groups, the first one includes the inhibitors inspired by the chemical structures of FAAH substrates, which carry an arachidonoyl-, oleoyl- or palmitoyl-carbon chain that mimic the fatty acid chains of anandamide, oleamide and palmitoylethanolamide. Carbon 197-203 fatty acid amide hydrolase Homo sapiens 0-4 21730521-1 2008 We developed integrated, carbon-based pipettes with nanoscale dimensions (CNP) that can probe cells with minimal intrusion, inject fluids into the cells, and concurrently carry out electrical measurements. Carbon 25-31 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 74-77 18560606-13 2008 Both ABCB1- and ABCC1-related fluorescence increased along with the carbon chain in acids from C(6) up to C(9) and decreased for C(10). Carbon 68-74 ATP binding cassette subfamily B member 1 Homo sapiens 5-10 18560606-13 2008 Both ABCB1- and ABCC1-related fluorescence increased along with the carbon chain in acids from C(6) up to C(9) and decreased for C(10). Carbon 68-74 ATP binding cassette subfamily C member 1 Homo sapiens 16-21 18924190-1 2008 Enantioselective allylic alkylation with an organomagnesium reagent catalyzed by copper thiophene carboxylate (CuTC) was carried out on difunctionalized substrates, such as commercially available 1,4-dichloro-2-butene and 1,4-dibromo-2-butene, and on similar compounds of higher substitution pattern of the olefin for the formation of all-carbon chiral quaternary centers. Carbon 339-345 cutC copper transporter Homo sapiens 111-115 18033704-0 2008 Coordination-driven self-assembly, structures, and dynamic properties of diplatinum hexatriynediyl and butadiynediyl complexes in which the sp carbon chains are shielded by sp3 carbon chains: towards endgroup-endgroup interactions. Carbon 177-183 Sp3 transcription factor Homo sapiens 173-176 18289091-5 2008 FAAH inhibitors can be divided in two major groups, the first one includes the inhibitors inspired by the chemical structures of FAAH substrates, which carry an arachidonoyl-, oleoyl- or palmitoyl-carbon chain that mimic the fatty acid chains of anandamide, oleamide and palmitoylethanolamide. Carbon 197-203 fatty acid amide hydrolase Homo sapiens 129-133 18468058-2 2008 Carbon nanotubes possess a high Young"s modulus (1 TPa) and breaking strains of 5-15%. Carbon 0-6 plasminogen activator, tissue type Homo sapiens 51-54 18154315-2 2008 Only the alternating pattern of single-double carbon bonds within the sp2 carbon ribbons provides a satisfactory explanation for the experimentally observed blue shift of the G band of the Raman spectra relative to graphite. Carbon 46-52 Sp2 transcription factor Homo sapiens 70-73 18154315-2 2008 Only the alternating pattern of single-double carbon bonds within the sp2 carbon ribbons provides a satisfactory explanation for the experimentally observed blue shift of the G band of the Raman spectra relative to graphite. Carbon 74-80 Sp2 transcription factor Homo sapiens 70-73 18154315-3 2008 To obtain these single-double bonds, it is necessary to have sp3 carbons on the edges of a zigzag carbon ribbon. Carbon 65-72 Sp3 transcription factor Homo sapiens 61-64 18154315-3 2008 To obtain these single-double bonds, it is necessary to have sp3 carbons on the edges of a zigzag carbon ribbon. Carbon 65-71 Sp3 transcription factor Homo sapiens 61-64 20641770-0 2004 Single-walled carbon nanotubes-(111)In-1,4,7,10-tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid-rituximab The single-walled carbon nanotube-(111)In-labeled1,4,7,10-tetraazacyclododecane-N,N",N"",N"""-tetraacetic acid -rituximab (CNT-([(111)In]DOTA)(rituximab) is a nanoconstruct with multiple copies of the (111)In-labeled DOTA chelate and anti-CD20 monoclonal antibody (MAb) independently attached covalently to the CNT-sidewall and can be used for imaging lymphoid malignancies (1). Carbon 14-20 keratin 20 Homo sapiens 350-354 17579816-3 2008 The inactivation of GABA is brought about by high affinity GABA transporters located in the presynaptic GABAergic neurons as well as surrounding astrocytes and subsequently GABA may be metabolized by GABA-transaminase (GABA-T) ultimately allowing the carbon skeleton to enter the tricarboxylic acid (TCA) cycle for oxidative metabolism. Carbon 251-257 4-aminobutyrate aminotransferase Homo sapiens 200-217 17579816-3 2008 The inactivation of GABA is brought about by high affinity GABA transporters located in the presynaptic GABAergic neurons as well as surrounding astrocytes and subsequently GABA may be metabolized by GABA-transaminase (GABA-T) ultimately allowing the carbon skeleton to enter the tricarboxylic acid (TCA) cycle for oxidative metabolism. Carbon 251-257 4-aminobutyrate aminotransferase Homo sapiens 219-225 18855752-2 2008 This aptasensor based on multiwalled carbon nanotubes allowed us to detect thrombin with detection limit of 0.3 nM, which was 3 times better in comparison with conventional aptamer. Carbon 37-43 coagulation factor II, thrombin Homo sapiens 75-83 18044975-4 2007 We propose that these observations result from the binding of heme in form beta with an orientation that differs from the crystallographically observed binding orientation for rabbit hemopexin by rotation of the heme prosthetic group by 180 degrees about the alpha-gamma meso-carbon axis and from interaction of metal ions at two separate binding sites. Carbon 276-282 hemopexin Oryctolagus cuniculus 183-192 17868683-0 2007 Mechanism study on adsorption of acidified multiwalled carbon nanotubes to Pb(II). Carbon 55-61 submaxillary gland androgen regulated protein 3B Homo sapiens 75-81 17868683-1 2007 Adsorption of acidified multiwalled carbon nanotubes (MWCNTs) to heavy metal using Pb(II) as a model was investigated and characterized by many techniques. Carbon 36-42 submaxillary gland androgen regulated protein 3B Homo sapiens 83-89 17931867-1 2007 A variety of macrocyclic urea compounds were prepared as potent Chk1 inhibitors by modifying the C5 position of the benzene ring of the macrocyclic urea with ether moieties, aliphatic carbon chains, amide and halides. Carbon 184-190 checkpoint kinase 1 Homo sapiens 64-68 18001098-1 2007 DFT/B3LYP calculations have been carried out to study intramolecular 1,n palladium shifts (n = 3-5) between sp2 and sp3 carbon atoms in alkylarylpalladium systems. Carbon 120-126 Sp3 transcription factor Homo sapiens 116-119 18001098-7 2007 All of these results are in line with our previous results for palladium shifts between two sp2 carbon atoms. Carbon 96-102 Sp2 transcription factor Homo sapiens 92-95 18290429-4 2007 Average removal ratio of PAEs was 99.1% for the solution containing 12 mg x L(-1) DMP, DEP, DBP, DOP respectively by the activated carbon-Fenton process for 15 h. Carbon 131-137 D-box binding PAR bZIP transcription factor Homo sapiens 92-95 17989693-5 2007 These pathways differentially activate the two PAS kinase proteins in Saccharomyces cerevisiae, Psk1 and Psk2, with Psk1 alone responding to activation by nonfermentative carbon sources. Carbon 171-177 serine/threonine protein kinase PSK1 Saccharomyces cerevisiae S288C 96-100 18371631-0 2007 Direct electrochemistry and electrocatalysis of cytochrome c immobilized on gold nanoparticles-chitosan-carbon nanotubes-modified electrode. Carbon 104-110 cytochrome c, somatic Homo sapiens 48-60 18371631-2 2007 Cytochrome c (Cyt c) was successfully immobilized on the nanohybrid film modified glassy carbon (GC) electrode by cyclic voltammetry. Carbon 89-95 cytochrome c, somatic Homo sapiens 0-12 18371631-2 2007 Cytochrome c (Cyt c) was successfully immobilized on the nanohybrid film modified glassy carbon (GC) electrode by cyclic voltammetry. Carbon 89-95 cytochrome c, somatic Homo sapiens 14-19 27517826-4 2007 When COD/NO3 (-)-N ratio (C/N) was in the range 5-30, the removal of benzene was slightly influenced by C/N and it remained stable at about 90%. Carbon 5-6 NBL1, DAN family BMP antagonist Homo sapiens 9-12 27517826-4 2007 When COD/NO3 (-)-N ratio (C/N) was in the range 5-30, the removal of benzene was slightly influenced by C/N and it remained stable at about 90%. Carbon 26-27 NBL1, DAN family BMP antagonist Homo sapiens 9-12 17989693-5 2007 These pathways differentially activate the two PAS kinase proteins in Saccharomyces cerevisiae, Psk1 and Psk2, with Psk1 alone responding to activation by nonfermentative carbon sources. Carbon 171-177 serine/threonine protein kinase PSK1 Saccharomyces cerevisiae S288C 116-120 18006776-1 2007 PURPOSE: 1,1-Bis(3"-indolyl)-1-(p-substitutedphenyl)methanes [methylene-substituted diindolylmethanes (C-DIM)] containing p-trifluoromethyl, p-t-butyl, and p-phenyl substituents activate peroxisome proliferator-activated receptor gamma (PPARgamma) and inhibit growth of several different cancer cell lines through receptor-dependent and receptor-independent pathways. Carbon 103-104 peroxisome proliferator activated receptor gamma Homo sapiens 187-235 18006776-1 2007 PURPOSE: 1,1-Bis(3"-indolyl)-1-(p-substitutedphenyl)methanes [methylene-substituted diindolylmethanes (C-DIM)] containing p-trifluoromethyl, p-t-butyl, and p-phenyl substituents activate peroxisome proliferator-activated receptor gamma (PPARgamma) and inhibit growth of several different cancer cell lines through receptor-dependent and receptor-independent pathways. Carbon 103-104 peroxisome proliferator activated receptor gamma Homo sapiens 237-246 17963841-1 2007 A highly sensitive and label-free amperometric immunosensor has been developed for the detection of carcinoembryonic antigen (CEA) based on layer-by-layer (LBL) assembly of gold nanoparticles (GNPs), multi-walled carbon nanotubes-thionine (MWNTs-THI) and chitosan (CHIT) on 3-mercaptopropanesulfonic, sodium salt (MPS)-modified gold electrode surface by electrostatic adsorption. Carbon 213-219 CEA cell adhesion molecule 3 Homo sapiens 100-124 17963841-1 2007 A highly sensitive and label-free amperometric immunosensor has been developed for the detection of carcinoembryonic antigen (CEA) based on layer-by-layer (LBL) assembly of gold nanoparticles (GNPs), multi-walled carbon nanotubes-thionine (MWNTs-THI) and chitosan (CHIT) on 3-mercaptopropanesulfonic, sodium salt (MPS)-modified gold electrode surface by electrostatic adsorption. Carbon 213-219 CEA cell adhesion molecule 3 Homo sapiens 126-129 17929966-3 2007 A polymer conjugated to the 4-hydroxytamoxifen analogue with a six-carbon linker showed high affinity for both estrogen receptor alpha and estrogen receptor beta and potent antagonism of the estrogen receptor in cell-based transcriptional reporter assays. Carbon 67-73 estrogen receptor 1 Homo sapiens 111-134 17706277-0 2007 Enhanced fibronectin adsorption on carbon nanotube/poly(carbonate) urethane: independent role of surface nano-roughness and associated surface energy. Carbon 35-41 fibronectin 1 Homo sapiens 9-20 17706277-1 2007 The contribution of nanoscale surface roughness on the adsorption of one key cell adhesive protein, fibronectin, on carbon nanotube/poly(carbonate) urethane composites of different surface energies was evaluated. Carbon 116-122 fibronectin 1 Homo sapiens 100-111 17929966-3 2007 A polymer conjugated to the 4-hydroxytamoxifen analogue with a six-carbon linker showed high affinity for both estrogen receptor alpha and estrogen receptor beta and potent antagonism of the estrogen receptor in cell-based transcriptional reporter assays. Carbon 67-73 estrogen receptor 1 Homo sapiens 111-128 17973536-0 2007 C-C, C-O, C-N bond formation on sp2 carbon by Pd(II)-catalyzed reactions involving oxidant agents. Carbon 0-1 Sp2 transcription factor Homo sapiens 32-35 17598073-2 2007 Transketolase catalyses the enantioselective carbon-carbon bond formation of chiral keto-diol products. Carbon 45-51 transketolase Homo sapiens 0-13 17598073-2 2007 Transketolase catalyses the enantioselective carbon-carbon bond formation of chiral keto-diol products. Carbon 52-58 transketolase Homo sapiens 0-13 17973536-0 2007 C-C, C-O, C-N bond formation on sp2 carbon by Pd(II)-catalyzed reactions involving oxidant agents. Carbon 2-3 Sp2 transcription factor Homo sapiens 32-35 17973536-0 2007 C-C, C-O, C-N bond formation on sp2 carbon by Pd(II)-catalyzed reactions involving oxidant agents. Carbon 2-3 Sp2 transcription factor Homo sapiens 32-35 17973536-0 2007 C-C, C-O, C-N bond formation on sp2 carbon by Pd(II)-catalyzed reactions involving oxidant agents. Carbon 36-42 Sp2 transcription factor Homo sapiens 32-35 17875938-3 2007 While we observed that Rds2 binds to only a few promoters in glucose-containing medium, it binds many additional genes when the medium is shifted to ethanol, a nonfermentable carbon source. Carbon 175-181 Rds2p Saccharomyces cerevisiae S288C 23-27 17937387-5 2007 A real-time polymerase chain reaction analysis of 10 genes in the one-carbon metabolism pathway revealed that 5,10-methylenetetrahydrofolate reductase, S-adenosylhomocysteine hydrolase (Ahcy), and formiminotransferase cyclodeaminase (Ftcd) were significantly down-regulated in Gnmt-/- mice. Carbon 70-76 methylenetetrahydrofolate reductase Mus musculus 110-150 17937387-5 2007 A real-time polymerase chain reaction analysis of 10 genes in the one-carbon metabolism pathway revealed that 5,10-methylenetetrahydrofolate reductase, S-adenosylhomocysteine hydrolase (Ahcy), and formiminotransferase cyclodeaminase (Ftcd) were significantly down-regulated in Gnmt-/- mice. Carbon 70-76 formiminotransferase cyclodeaminase Mus musculus 197-232 17937387-5 2007 A real-time polymerase chain reaction analysis of 10 genes in the one-carbon metabolism pathway revealed that 5,10-methylenetetrahydrofolate reductase, S-adenosylhomocysteine hydrolase (Ahcy), and formiminotransferase cyclodeaminase (Ftcd) were significantly down-regulated in Gnmt-/- mice. Carbon 70-76 formiminotransferase cyclodeaminase Mus musculus 234-238 17879105-3 2007 In SP-HPLC and chiral phase-HPLC analyses, the products from the oxygenation of docosahexaenoyl-lysoPC by soybean LOX-1 and porcine leukocyte LOX were found to contain hydroperoxide group mainly at C-17 and C-14, respectively with the S form as a major enantiomer. Carbon 9-10 seed linoleate 13S-lipoxygenase-1 Glycine max 114-119 17879105-3 2007 In SP-HPLC and chiral phase-HPLC analyses, the products from the oxygenation of docosahexaenoyl-lysoPC by soybean LOX-1 and porcine leukocyte LOX were found to contain hydroperoxide group mainly at C-17 and C-14, respectively with the S form as a major enantiomer. Carbon 9-10 seed linoleate 9S-lipoxygenase-3 Glycine max 114-117 17879105-3 2007 In SP-HPLC and chiral phase-HPLC analyses, the products from the oxygenation of docosahexaenoyl-lysoPC by soybean LOX-1 and porcine leukocyte LOX were found to contain hydroperoxide group mainly at C-17 and C-14, respectively with the S form as a major enantiomer. Carbon 31-32 seed linoleate 13S-lipoxygenase-1 Glycine max 114-119 17879105-3 2007 In SP-HPLC and chiral phase-HPLC analyses, the products from the oxygenation of docosahexaenoyl-lysoPC by soybean LOX-1 and porcine leukocyte LOX were found to contain hydroperoxide group mainly at C-17 and C-14, respectively with the S form as a major enantiomer. Carbon 31-32 seed linoleate 9S-lipoxygenase-3 Glycine max 114-117 17875938-6 2007 We also show that the purified DNA binding domain of Rds2 binds in vitro to carbon source response elements found in the promoters of target genes. Carbon 76-82 Rds2p Saccharomyces cerevisiae S288C 53-57 17885092-10 2007 AtALMT1 promoter-beta-glucuronidase fusion lines revealed that AtALMT1 has restricted expression within the root, such that unnecessary carbon loss is likely minimized. Carbon 136-142 aluminum-activated malate transporter 1 Arabidopsis thaliana 0-7 17885092-10 2007 AtALMT1 promoter-beta-glucuronidase fusion lines revealed that AtALMT1 has restricted expression within the root, such that unnecessary carbon loss is likely minimized. Carbon 136-142 aluminum-activated malate transporter 1 Arabidopsis thaliana 63-70 17935400-6 2007 The C 1s core-level spectra of alaninol and isopropanolamine are reported and the peak positions of the three carbon atoms of the molecules are assigned. Carbon 110-116 complement C1s Homo sapiens 4-8 17617417-2 2007 The characterization of carbon/silver samples was studied by BET, FTIR, X-ray diffraction, XPS, and SEM techniques. Carbon 24-30 putative DNA recombination protein Bet Escherichia coli 61-64 17982599-5 2007 By biochemical implications and derivations, it is most likely that mycotoxins interrupt the structure and function of vitamin B12 through reactive interference with the normal One-Carbon metabolism leading to the observed clinical neurological manifestations such as nerve damage and, demyelination, degeneration of PNS leading to paralysis, progressive peripheral neuropathy, and spinal degeneration. Carbon 181-187 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 127-130 17824676-0 2007 Role of the C-H stretch mode excitation in the dynamics of the Cl + CHD3 reaction: a quasi-classical trajectory calculation. Carbon 12-13 chromodomain helicase DNA binding protein 3 Homo sapiens 68-72 17825957-1 2007 In this study, we exploited a crp (cAMP receptor protein) gene-deleted, virulence plasmid-cured Salmonella choleraesuis mutant with decreased carbon source utilization, designated S.C.-Deltacrp/vpl(-), as a live vaccine strain. Carbon 142-148 C-reactive protein Sus scrofa 30-33 17824676-1 2007 To analyze the effect of the C-H stretch mode excitation on the dynamics of the Cl + CHD3 gas-phase abstraction reaction, an exhaustive state-to-state dynamics study was performed. Carbon 29-30 chromodomain helicase DNA binding protein 3 Homo sapiens 85-89 17824679-3 2007 Our efforts toward identifying novel small-molecule peptidomimetic renin inhibitors have resulted in the design of transition-state isosteres such as 1 bearing an all-carbon 8-phenyl-octanecarboxamide framework. Carbon 167-173 renin Homo sapiens 67-72 17713644-5 2007 Rats continuously breathing polluted air for 20 h (P-20) showed a significant increase in the total number of leukocytes in bronchoalveolar lavage compared to control (C-20: 2.61 x 105 +/- 0.51;P-20: 5.01 x 105 +/- 0.81; P < 0.05) and in lipid peroxidation ([MDA] nmol/mg protein: C-20: 0.148 +/- 0.01; P-20: 0.226 +/- 0.02; P < 0.05). Carbon 168-169 heat shock protein family B (small) member 6 Rattus norvegicus 51-55 17715992-0 2007 Picomolar detection of insulin at renewable nickel powder-doped carbon composite electrode. Carbon 64-70 insulin Homo sapiens 23-30 17685375-1 2007 A series of highly ordered mesoporous carbonaceous frameworks with diverse symmetries have been successfully synthesized by using phenolic resols as a carbon precursor and mixed amphiphilic surfactants of poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (PEO-PPO-PEO) and reverse PPO-PEO-PPO as templates by the strategy of evaporation-induced organic-organic self-assembly (EISA). Carbon 38-44 protoporphyrinogen oxidase Homo sapiens 278-281 17685375-1 2007 A series of highly ordered mesoporous carbonaceous frameworks with diverse symmetries have been successfully synthesized by using phenolic resols as a carbon precursor and mixed amphiphilic surfactants of poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (PEO-PPO-PEO) and reverse PPO-PEO-PPO as templates by the strategy of evaporation-induced organic-organic self-assembly (EISA). Carbon 38-44 protoporphyrinogen oxidase Homo sapiens 299-302 17685375-1 2007 A series of highly ordered mesoporous carbonaceous frameworks with diverse symmetries have been successfully synthesized by using phenolic resols as a carbon precursor and mixed amphiphilic surfactants of poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (PEO-PPO-PEO) and reverse PPO-PEO-PPO as templates by the strategy of evaporation-induced organic-organic self-assembly (EISA). Carbon 38-44 protoporphyrinogen oxidase Homo sapiens 299-302 18179746-4 2007 The present study investigates the effects of pulmonary exposure to two sizes of carbon nanoparticles on lung physiology and lung expression of Muc5ac in the presence or absence of antigen in mice. Carbon 81-87 mucin 5, subtypes A and C, tracheobronchial/gastric Mus musculus 144-150 17712601-4 2007 The smaller AtCOX19-1 isoform, but not the larger one, is able to restore growth on non-fermentable carbon sources when expressed in a yeast cox19 null mutant. Carbon 100-106 Cox19p Saccharomyces cerevisiae S288C 141-146 17719234-6 2007 Introduction of anions more basic than O(2)(-*), i.e., C(6)H(5)CH(2)(-), into the APPI source, via addition of di-tert-butyl peroxide in the solvent and/or dopant, i.e., toluene, enhanced the deprotonation ability of negative ion-APPI. Carbon 55-56 amyloid beta precursor protein Homo sapiens 82-86 17626977-10 2007 Therefore, the preferred acceptor molecules for LPLA2 are primary alcohols with one long carbon chain and one small nonpolar residue linked to the C2 position of ethanol. Carbon 89-95 phospholipase A2 group XV Homo sapiens 48-53 17718472-2 2007 One series of oligomers, Ptn, has the general structure Ph-C[triple bond]C-[Pt(PBu3)2-C[triple bond]C-(1,4-Ph)-C[triple bond]C-]n-Pt(PBu3)2-C[triple bond]C-Ph (where x=0-4, Ph=phenyl and 1,4-Ph=1,4-phenylene). Carbon 73-74 pleiotrophin Homo sapiens 25-28 17803274-0 2007 Ruthenium catalyzed decarbonylative arylation at sp3 carbon centers in pyrrolidine and piperidine heterocycles. Carbon 22-28 Sp3 transcription factor Homo sapiens 49-52 17803274-1 2007 This paper describes the development of a new catalytic transformation, the ruthenium-catalyzed decarbonylative arylation of cyclic 2-amino esters, which replaces the ester group with an aryl ring at the sp3 carbon center. Carbon 98-104 Sp3 transcription factor Homo sapiens 204-207 17718472-2 2007 One series of oligomers, Ptn, has the general structure Ph-C[triple bond]C-[Pt(PBu3)2-C[triple bond]C-(1,4-Ph)-C[triple bond]C-]n-Pt(PBu3)2-C[triple bond]C-Ph (where x=0-4, Ph=phenyl and 1,4-Ph=1,4-phenylene). Carbon 59-60 pleiotrophin Homo sapiens 25-28 17718472-2 2007 One series of oligomers, Ptn, has the general structure Ph-C[triple bond]C-[Pt(PBu3)2-C[triple bond]C-(1,4-Ph)-C[triple bond]C-]n-Pt(PBu3)2-C[triple bond]C-Ph (where x=0-4, Ph=phenyl and 1,4-Ph=1,4-phenylene). Carbon 73-74 pleiotrophin Homo sapiens 25-28 17718472-2 2007 One series of oligomers, Ptn, has the general structure Ph-C[triple bond]C-[Pt(PBu3)2-C[triple bond]C-(1,4-Ph)-C[triple bond]C-]n-Pt(PBu3)2-C[triple bond]C-Ph (where x=0-4, Ph=phenyl and 1,4-Ph=1,4-phenylene). Carbon 73-74 pleiotrophin Homo sapiens 25-28 17849370-7 2007 We here report, for the first time, that the prosthetic material surface (non-phagocytable) of as-cast high carbon CoCrMo reduces the pro-inflammatory cytokine IL-6 transcription, the chemokine MCP-1 secretion, and M-CSF secretion by 77%, 36%, and 62%, respectively. Carbon 108-114 interleukin 6 Mus musculus 160-164 17590341-5 2007 By varying the side-chain length of the aldehyde-functionalized amino acid, we found that the optimal transglutaminase 2 inhibitor was 5 methylene units in length, 2 carbon atoms longer than its natural glutamine substrate. Carbon 166-172 transglutaminase 2 Homo sapiens 102-120 17849370-7 2007 We here report, for the first time, that the prosthetic material surface (non-phagocytable) of as-cast high carbon CoCrMo reduces the pro-inflammatory cytokine IL-6 transcription, the chemokine MCP-1 secretion, and M-CSF secretion by 77%, 36%, and 62%, respectively. Carbon 108-114 mast cell protease 1 Mus musculus 194-199 17690534-2 2007 To the authors" knowledge, this is the first study demonstrating gene expression in association with PLD repair after carbon-ion beam or X-ray irradiation to cancer cells. Carbon 118-124 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 101-104 17628321-1 2007 This work describes the performance of cytochrome c/nickel oxide nanoparticles/glassy carbon electrode, prepared by the electrochemical deposition of the nickel oxide nanoparticles (NiO NPs) on the glassy carbon (GC) electrode surface and the cytochrome c immobilization on the nickel oxide nanoparticle surfaces. Carbon 205-211 cytochrome c, somatic Homo sapiens 39-51 17596206-2 2007 Functional polymorphisms in genes encoding one-carbon metabolism enzymes, such as methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), methionine synthase (MTR A2756G), methionine synthase reductase (MTRR A66G) and thymidylate synthase (TS), influence folate metabolism and thus might impact on HNSCC risk. Carbon 47-53 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 178-207 17700259-10 2007 The carbon ions had a stronger effect on p53 and p21 expression than the gamma-ray irradiation. Carbon 4-10 tumor protein p53 Homo sapiens 41-44 17544053-0 2007 Immobilization of polyphenol oxidase onto mesoporous activated carbons -- isotherm and kinetic studies. Carbon 63-70 protoporphyrinogen oxidase Homo sapiens 18-36 17544053-1 2007 Investigations were carried out in batch modes for studying the immobilization behavior of polyphenol oxidase (PPO) on two different mesoporous activated carbon matrices, MAC400 and MAC200. Carbon 154-160 protoporphyrinogen oxidase Homo sapiens 91-109 17544053-7 2007 The immobilization of PPO in carbon matrices was confirmed using FT-IR spectroscopy and scanning electron microscopy. Carbon 29-35 protoporphyrinogen oxidase Homo sapiens 22-25 17937296-1 2007 River systems draining peaty catchments are considered a source of atmospheric CO2,thus understanding the behavior of the dissolved inorganic carbon pool (DIC) is valuable. Carbon 142-148 solute carrier family 25 member 10 Homo sapiens 155-158 17690534-5 2007 Second, to search the genes causing PLD repair after irradiation of X-ray or carbon-ion beam, we evaluated gene expressions by using semi-quantitative RT-PCR with the selected 34 genes reportedly related to DNA repair. Carbon 77-83 glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens 36-39 17690534-10 2007 The genes showing significantly lower expressions after X-ray irradiation rather than after carbon-ion beam irradiation were RAD50, BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. Carbon 92-98 MRE11 homolog, double strand break repair nuclease Homo sapiens 139-145 17690534-10 2007 The genes showing significantly lower expressions after X-ray irradiation rather than after carbon-ion beam irradiation were RAD50, BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. Carbon 92-98 checkpoint kinase 1 Homo sapiens 154-159 17651371-6 2007 We observed rapid shutdown of carbon fixation in chloroplasts after SIPK/Ntf4/WIPK activation, which can lead to the generation of ROS in chloroplasts under illumination. Carbon 30-36 neurotrophin 4 Homo sapiens 73-77 17700863-0 2007 Transcript and proteomic analyses of wild-type and gpa2 mutant Saccharomyces cerevisiae strains suggest a role for glycolytic carbon source sensing in pseudohyphal differentiation. Carbon 126-132 guanine nucleotide-binding protein subunit alpha Saccharomyces cerevisiae S288C 51-55 17767357-3 2007 LX epimers at carbon 15, the 15-epi-LXs, are formed by aspirin-acetylated cyclooxygenase-2 (COX-2) in cooperation with 5-LO. Carbon 14-20 prostaglandin-endoperoxide synthase 2 Homo sapiens 74-90 17767357-3 2007 LX epimers at carbon 15, the 15-epi-LXs, are formed by aspirin-acetylated cyclooxygenase-2 (COX-2) in cooperation with 5-LO. Carbon 14-20 prostaglandin-endoperoxide synthase 2 Homo sapiens 92-97 17618651-5 2007 In vivo complementation analyses using a MET3-TIM10 strain that is selectively inactivated for the expression of wild-type Tim10 showed that (i) an N-terminal deleted version of Tim10 that was previously shown to be defective in substrate binding is lethal under all conditions, but (ii) the charged residues mutant of Tim10 that is defective in assembly with Tim9 can restore growth in glucose, but not in non-fermentable carbon sources. Carbon 423-429 protein transporter TIM10 Saccharomyces cerevisiae S288C 178-183 17618651-5 2007 In vivo complementation analyses using a MET3-TIM10 strain that is selectively inactivated for the expression of wild-type Tim10 showed that (i) an N-terminal deleted version of Tim10 that was previously shown to be defective in substrate binding is lethal under all conditions, but (ii) the charged residues mutant of Tim10 that is defective in assembly with Tim9 can restore growth in glucose, but not in non-fermentable carbon sources. Carbon 423-429 protein transporter TIM10 Saccharomyces cerevisiae S288C 178-183 17666827-8 2007 These observations suggested that fatty acids showed the variable inhibitory effects on CYP3A-mediated testosterone oxidation and that the number of double bonds, as well as the carbon chain lengths of fatty acids, may be important in the inhibition of CYP3A. Carbon 178-184 cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus 253-258 17662499-5 2007 Fructose uptake by the GLUT5 transporter should supply sugar to cells at a more moderate rate, even in high fructose concentrations, avoiding the overflow of excess carbon to lactate. Carbon 165-171 solute carrier family 2 member 5 Homo sapiens 23-28 17649980-5 2007 Insertional disruption of the gene encoding STM3697 abolishes this phenotype; this disruption also diminishes, but does not eliminate, the ability of the organism to utilize galactarate as carbon source. Carbon 189-195 mandelate racemase/muconate lactonizing protein Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 44-51 17893649-12 2007 In contrast, expression of HCCS E159K did not complement respiratory growth of the CYC3-deficient yeast strain B-8025, while wild-type HCCS and the yeast heme lyase Cyc3p could rescue growth on nonfermentable carbon sources. Carbon 209-215 holocytochrome c synthase Homo sapiens 27-31 17663535-0 2007 A new insight into using chlorine leaving group and nucleophile carbon kinetic isotope effects to determine substituent effects on the structure of SN2 transition states. Carbon 64-70 solute carrier family 38 member 5 Homo sapiens 148-151 19071847-0 2007 High selective SiO2-Al2O3 mixed-oxide modified carbon paste electrode for anodic stripping voltammetric determination of Pb(II). Carbon 47-53 submaxillary gland androgen regulated protein 3B Homo sapiens 121-127 19071847-1 2007 The main purpose of this study is to develop an inexpensive, simple, selective and especially highly selective modified mixed-oxide carbon paste electrode (CPE) for voltammetric determination of Pb(II). Carbon 132-138 submaxillary gland androgen regulated protein 3B Homo sapiens 195-201 19071847-3 2007 Using cyclic voltammetry the electroanalytical characteristics of the catalyst have been determined, and consequently the modified mixed-oxide carbon paste electrode was constructed and applied for determination of Pb(II). Carbon 143-149 submaxillary gland androgen regulated protein 3B Homo sapiens 215-221 19071865-1 2007 In this study, we investigate highly efficient sonogel carbon electrode (SGC/TiO(2)) modified with nanostructured titanium dioxide synthesized via sol-gel method employing surfactant template for tailor-designing the structural properties of TiO(2). Carbon 55-61 sarcoglycan beta Homo sapiens 73-76 17503834-3 2007 The key steps used in the synthesis include the sp3-hybridized carbon-carbon Fu cross coupling, the stereoselective Evans" aldol reaction with 1,5-anti induction, the 1,3-diastereoselective syn reduction of a beta-hydroxyketone intermediate, and Mukaiyama macrolactonization reactions. Carbon 63-69 Sp3 transcription factor Homo sapiens 48-51 17503466-7 2007 When K20S-mutant mVDAC1 was expressed in porin1-less yeast, the transformed cells grew slower on non-fermentable carbon sources, while isolated mitochondria expressing either mVDAC1 mutant showed significant reduction in ATP synthesis. Carbon 113-119 voltage-dependent anion channel 1 Mus musculus 17-23 17580861-1 2007 In this Article, we describe a carbon nanotube formation model in which sp2 carbon hemispheres form the embryonic caps from which a nanotube can grow. Carbon 31-37 Sp2 transcription factor Homo sapiens 72-75 17580861-1 2007 In this Article, we describe a carbon nanotube formation model in which sp2 carbon hemispheres form the embryonic caps from which a nanotube can grow. Carbon 76-82 Sp2 transcription factor Homo sapiens 72-75 17564600-2 2007 In this study, fractionation of stable carbon isotope values of 1,2-DCA during biodegradation was used as a novel reaction probe to provide information about the mechanism of 1,2-DCA biodegradation under both aerobic (O2-reducing) and anaerobic (NO3-reducing) conditions. Carbon 39-45 NBL1, DAN family BMP antagonist Homo sapiens 246-249 17687709-3 2007 METHOD: The physiology of the one-carbon cycle, involving folate, cobalamin, homocysteine, S-adenosyl-methionine, and methylene tetrahydrofolate reductase (MTHFR) is first reviewed, and then the particular contributions of folate and B12 are reviewed. Carbon 34-40 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 234-237 17663266-11 2007 Studies carried out on the effect of SWCNT on superoxide dismutase (SOD-1 and SOD-2) levels in LE cells, indicates that these enzyme levels decreased by 24 hours. Carbon 37-42 superoxide dismutase 1 Rattus norvegicus 68-73 17677972-0 2007 Enhancing mechanical properties of multiwall carbon nanotubes via sp3 interwall bridging. Carbon 45-51 Sp3 transcription factor Homo sapiens 66-69 17345630-3 2007 This suggests a significant increase in the size of the enzyme hydrophobic tunnel from approximately 1000 A(3) of E. coli UPPs to approximately 1300 A(3) required to accommodate C(80) in Rer2p and to 1700 A(3) for C(110) in Srt1p. Carbon 178-179 ditrans,polycis-polyprenyl diphosphate synthase Saccharomyces cerevisiae S288C 224-229 18048020-4 2007 CNTO2424 down-regulates poly(I:C)-induced production of IL-6, IL-8, MCP-1, RANTES, and IP-10 in human lung epithelial cells. Carbon 0-1 interleukin 6 Homo sapiens 56-60 18048020-4 2007 CNTO2424 down-regulates poly(I:C)-induced production of IL-6, IL-8, MCP-1, RANTES, and IP-10 in human lung epithelial cells. Carbon 0-1 C-X-C motif chemokine ligand 8 Homo sapiens 62-66 17576645-0 2007 In situ detection of chromogranin a released from living neurons with a single-walled carbon-nanotube field-effect transistor. Carbon 86-92 chromogranin A Homo sapiens 21-35 17388388-5 2007 Comparison of the transition structures and energetics for the ion pair SN2 at sulfur with the potential competition ion pair SN2 reactions at carbon LiX+CH3SX-->XCH3+LiXS shows that the SN2 reactions at carbon are not favorable from the viewpoints of kinetics and thermodynamics. Carbon 143-149 solute carrier family 38 member 5 Homo sapiens 126-129 17388388-5 2007 Comparison of the transition structures and energetics for the ion pair SN2 at sulfur with the potential competition ion pair SN2 reactions at carbon LiX+CH3SX-->XCH3+LiXS shows that the SN2 reactions at carbon are not favorable from the viewpoints of kinetics and thermodynamics. Carbon 143-149 solute carrier family 38 member 5 Homo sapiens 126-129 17388388-5 2007 Comparison of the transition structures and energetics for the ion pair SN2 at sulfur with the potential competition ion pair SN2 reactions at carbon LiX+CH3SX-->XCH3+LiXS shows that the SN2 reactions at carbon are not favorable from the viewpoints of kinetics and thermodynamics. Carbon 207-213 solute carrier family 38 member 5 Homo sapiens 72-75 17388388-5 2007 Comparison of the transition structures and energetics for the ion pair SN2 at sulfur with the potential competition ion pair SN2 reactions at carbon LiX+CH3SX-->XCH3+LiXS shows that the SN2 reactions at carbon are not favorable from the viewpoints of kinetics and thermodynamics. Carbon 207-213 solute carrier family 38 member 5 Homo sapiens 126-129 17388388-5 2007 Comparison of the transition structures and energetics for the ion pair SN2 at sulfur with the potential competition ion pair SN2 reactions at carbon LiX+CH3SX-->XCH3+LiXS shows that the SN2 reactions at carbon are not favorable from the viewpoints of kinetics and thermodynamics. Carbon 207-213 solute carrier family 38 member 5 Homo sapiens 126-129 17586112-1 2007 Electrodeposition of Pt-Pb nanoparticles (PtPbNPs) to multi-walled carbon nanotubes (MWCNTs) resulted in a stable PtPbNP/MWCNT nanocomposite with high electrocatalytic activity to glucose oxidation in either neutral or alkaline medium. Carbon 67-73 protein tyrosine phosphatase receptor type B Homo sapiens 21-26 17442494-3 2007 In further study, the oxygenation products of linoleoyl-lysoPC or linoleoyl-lysoPA were found to contain hydroperoxide group predominantly at C-13 with the S enantiomer as a major one, in a good agreement with the positional-specificity and stereo-selectivity of reticulocyte LOX or leukocyte LOX in oxygenation of linoleic acid. Carbon 61-62 linoleate 9S-lipoxygenase 2 Solanum tuberosum 276-279 17442494-3 2007 In further study, the oxygenation products of linoleoyl-lysoPC or linoleoyl-lysoPA were found to contain hydroperoxide group predominantly at C-13 with the S enantiomer as a major one, in a good agreement with the positional-specificity and stereo-selectivity of reticulocyte LOX or leukocyte LOX in oxygenation of linoleic acid. Carbon 61-62 linoleate 9S-lipoxygenase 2 Solanum tuberosum 293-296 17578514-3 2007 Binding of VWF in solution to immobilized A/C was inhibited by ristocetin and preincubation of platelets with A/C abolished ristocetin/VWF-induced platelet aggregation, indicating that the interaction of A/C with VWF is mediated by the VWA1 domain. Carbon 44-45 von Willebrand factor Homo sapiens 11-14 17578514-3 2007 Binding of VWF in solution to immobilized A/C was inhibited by ristocetin and preincubation of platelets with A/C abolished ristocetin/VWF-induced platelet aggregation, indicating that the interaction of A/C with VWF is mediated by the VWA1 domain. Carbon 44-45 von Willebrand factor Homo sapiens 135-138 17578514-3 2007 Binding of VWF in solution to immobilized A/C was inhibited by ristocetin and preincubation of platelets with A/C abolished ristocetin/VWF-induced platelet aggregation, indicating that the interaction of A/C with VWF is mediated by the VWA1 domain. Carbon 44-45 von Willebrand factor Homo sapiens 135-138 17481587-5 2007 Consistently, the accumulation and sensitivity to these drugs were restored upon incubation with the potent and specific ABCG2 transport inhibitors Ko143 and fumitremorgin C. Moreover, upon transfection into HEK293 cells, the wt Q141 ABCG2 allele displayed a significantly decreased accumulation of C-1311 and increased resistance to C-1305, C-1311 and mitoxantrone, when compared to the K141 ABCG2 transfectant. Carbon 0-1 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 121-126 17481587-5 2007 Consistently, the accumulation and sensitivity to these drugs were restored upon incubation with the potent and specific ABCG2 transport inhibitors Ko143 and fumitremorgin C. Moreover, upon transfection into HEK293 cells, the wt Q141 ABCG2 allele displayed a significantly decreased accumulation of C-1311 and increased resistance to C-1305, C-1311 and mitoxantrone, when compared to the K141 ABCG2 transfectant. Carbon 0-1 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 234-239 17481587-5 2007 Consistently, the accumulation and sensitivity to these drugs were restored upon incubation with the potent and specific ABCG2 transport inhibitors Ko143 and fumitremorgin C. Moreover, upon transfection into HEK293 cells, the wt Q141 ABCG2 allele displayed a significantly decreased accumulation of C-1311 and increased resistance to C-1305, C-1311 and mitoxantrone, when compared to the K141 ABCG2 transfectant. Carbon 0-1 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 234-239 17481587-5 2007 Consistently, the accumulation and sensitivity to these drugs were restored upon incubation with the potent and specific ABCG2 transport inhibitors Ko143 and fumitremorgin C. Moreover, upon transfection into HEK293 cells, the wt Q141 ABCG2 allele displayed a significantly decreased accumulation of C-1311 and increased resistance to C-1305, C-1311 and mitoxantrone, when compared to the K141 ABCG2 transfectant. Carbon 123-124 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 234-239 17481587-5 2007 Consistently, the accumulation and sensitivity to these drugs were restored upon incubation with the potent and specific ABCG2 transport inhibitors Ko143 and fumitremorgin C. Moreover, upon transfection into HEK293 cells, the wt Q141 ABCG2 allele displayed a significantly decreased accumulation of C-1311 and increased resistance to C-1305, C-1311 and mitoxantrone, when compared to the K141 ABCG2 transfectant. Carbon 123-124 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 234-239 17481587-5 2007 Consistently, the accumulation and sensitivity to these drugs were restored upon incubation with the potent and specific ABCG2 transport inhibitors Ko143 and fumitremorgin C. Moreover, upon transfection into HEK293 cells, the wt Q141 ABCG2 allele displayed a significantly decreased accumulation of C-1311 and increased resistance to C-1305, C-1311 and mitoxantrone, when compared to the K141 ABCG2 transfectant. Carbon 123-124 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 234-239 17481587-5 2007 Consistently, the accumulation and sensitivity to these drugs were restored upon incubation with the potent and specific ABCG2 transport inhibitors Ko143 and fumitremorgin C. Moreover, upon transfection into HEK293 cells, the wt Q141 ABCG2 allele displayed a significantly decreased accumulation of C-1311 and increased resistance to C-1305, C-1311 and mitoxantrone, when compared to the K141 ABCG2 transfectant. Carbon 123-124 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 234-239 17562012-5 2007 Specifically, we describe phylogenies of three core carbon metabolic enzymes: transketolase, glyceraldehyde-3-phosphate dehydrogenase and ribulose-5-phosphate-3-epimerase. Carbon 52-58 transketolase Homo sapiens 78-91 17562012-5 2007 Specifically, we describe phylogenies of three core carbon metabolic enzymes: transketolase, glyceraldehyde-3-phosphate dehydrogenase and ribulose-5-phosphate-3-epimerase. Carbon 52-58 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 93-133 17503834-3 2007 The key steps used in the synthesis include the sp3-hybridized carbon-carbon Fu cross coupling, the stereoselective Evans" aldol reaction with 1,5-anti induction, the 1,3-diastereoselective syn reduction of a beta-hydroxyketone intermediate, and Mukaiyama macrolactonization reactions. Carbon 70-76 Sp3 transcription factor Homo sapiens 48-51 17379515-3 2007 In vitro competitive binding assays for the estrogen receptor (alpha-ER), using [(3)H]estradiol (RBA=100) as a competitor, revealed that a two-carbon alkyl linker combined with a flavone conjugate provided the highest binding affinity (RBA approximately 9), warranting further studies on their potential use as selective estrogen-receptor modulators (SERMs) for hormone-replacement therapies. Carbon 143-149 estrogen receptor 1 Homo sapiens 44-61 17584613-0 2007 Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands. Carbon 54-60 estrogen receptor 1 Homo sapiens 116-133 17584613-0 2007 Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands. Carbon 61-67 estrogen receptor 1 Homo sapiens 116-133 17346854-5 2007 In addition, this will provide the alpha-ketoglutarate carbon skeleton for glutamate and glutamine synthesis by glutamate dehydrogenase and glutamine synthetase (astrocytes only), respectively, both reactions fixing ammonium. Carbon 55-61 glutamate-ammonia ligase (glutamine synthetase) Mus musculus 140-160 17654944-0 2007 Improved critical current density of MgB2--carbon nanotubes composite. Carbon 43-49 secretoglobin family 2A member 1 Homo sapiens 37-41 17654944-1 2007 In the present study, we report a systematic study of doping/admixing of carbon nanotubes (CNTs) in different concentrations in MgB2. Carbon 73-79 secretoglobin family 2A member 1 Homo sapiens 128-132 17654944-5 2007 The microstructural investigations reveal the formation of MgB2-carbon nanotube composites. Carbon 64-70 secretoglobin family 2A member 1 Homo sapiens 59-63 17584160-7 2007 Our screening of the discovery library identified potent PXR activators whose carbon scaffolds are distinct from the chemical structures of known PXR agonists. Carbon 78-84 nuclear receptor subfamily 1 group I member 2 Homo sapiens 57-60 17713070-1 2007 The first examples of transition metal mediated C-S cleavage of sulfoxides containing sp2- and sp3-hybridized carbon bonds attached to the sulfur atom and the first example of a structurally characterized complex featuring an oxygen-bound sulfinyl ligand are presented. Carbon 48-49 Sp2 transcription factor Homo sapiens 86-89 17713070-1 2007 The first examples of transition metal mediated C-S cleavage of sulfoxides containing sp2- and sp3-hybridized carbon bonds attached to the sulfur atom and the first example of a structurally characterized complex featuring an oxygen-bound sulfinyl ligand are presented. Carbon 48-49 Sp3 transcription factor Homo sapiens 95-98 17713070-1 2007 The first examples of transition metal mediated C-S cleavage of sulfoxides containing sp2- and sp3-hybridized carbon bonds attached to the sulfur atom and the first example of a structurally characterized complex featuring an oxygen-bound sulfinyl ligand are presented. Carbon 110-116 Sp3 transcription factor Homo sapiens 95-98 17444661-10 2007 The data give kcat/Km = 185 M-1 s-1 for turnover of glycolaldehyde by TIM that is saturated with phosphite dianion so that the separate binding of phosphite dianion to TIM results in a 700-fold acceleration of proton transfer from carbon. Carbon 231-237 triosephosphate isomerase 1 Homo sapiens 70-73 17444661-0 2007 Enzymatic catalysis of proton transfer at carbon: activation of triosephosphate isomerase by phosphite dianion. Carbon 42-48 triosephosphate isomerase 1 Homo sapiens 64-89 17444661-10 2007 The data give kcat/Km = 185 M-1 s-1 for turnover of glycolaldehyde by TIM that is saturated with phosphite dianion so that the separate binding of phosphite dianion to TIM results in a 700-fold acceleration of proton transfer from carbon. Carbon 231-237 triosephosphate isomerase 1 Homo sapiens 168-171 17444661-12 2007 We propose a physical model for catalysis by TIM in which the intrinsic binding energy of the substrate phosphodianion group is utilized to drive closing of the "mobile loop" and a protein conformational change that leads to formation of an active site environment that is optimally organized for stabilization of the transition state for proton transfer from alpha-carbonyl carbon. Carbon 366-372 triosephosphate isomerase 1 Homo sapiens 45-48 17359937-1 2007 In human myeloperoxidase (MPO) the heme is covalently attached to the protein via two ester linkages and a unique sulfonium ion linkage between the sulfur atom of Met243 and the beta-carbon of the vinyl ring on pyrrole ring A. Carbon 183-189 myeloperoxidase Homo sapiens 9-24 17419615-3 2007 On the other hand, the two complexes 1a and 1b contain a tetradentate-N2S2 ligand, which is created via ring opening of HL1 and H3L2, followed by bond formation between imino carbon atoms. Carbon 175-181 asialoglycoprotein receptor 1 Homo sapiens 120-123 17359937-1 2007 In human myeloperoxidase (MPO) the heme is covalently attached to the protein via two ester linkages and a unique sulfonium ion linkage between the sulfur atom of Met243 and the beta-carbon of the vinyl ring on pyrrole ring A. Carbon 183-189 myeloperoxidase Homo sapiens 26-29 17566334-1 2007 In this paper, a poly(styrene-octadecene-divinylbenzene) (PS-OD-DVB) monolithic column was prepared in one step by introducing a C18 carbon chain as monomer. Carbon 133-139 Bardet-Biedl syndrome 9 Homo sapiens 129-132 17419604-3 2007 N4-Substituted fatty acid amide prodrugs of 10-16 carbon chain length demonstrated significantly improved antitumor activity over l-1,3-dioxolane-cytidine. Carbon 50-56 immunoglobulin kappa variable 1-16 Homo sapiens 130-133 17566334-6 2007 The PS-OD-DVB monolith was found to have higher loading capacity and higher resolution for the separation of alpha and beta chains of hemoglobin because of the introduction of C18 carbon chains, and shows great potential for the separation of bio-macromolecules. Carbon 180-186 Bardet-Biedl syndrome 9 Homo sapiens 176-179 17371025-4 2007 The addition of NH to a parallel bond renders the functionalized carbons formally sp3-hybridized, yielding shifts of around 44 ppm, independent of the SWNT radius. Carbon 65-72 Sp3 transcription factor Homo sapiens 82-85 17371025-5 2007 Reaction with a diagonal bond retains the formal sp2 hybridization of the substituted carbons, and their shifts are slightly lower or higher than those of the unsubstituted carbon atoms. Carbon 86-93 Sp2 transcription factor Homo sapiens 49-52 17371025-5 2007 Reaction with a diagonal bond retains the formal sp2 hybridization of the substituted carbons, and their shifts are slightly lower or higher than those of the unsubstituted carbon atoms. Carbon 86-92 Sp2 transcription factor Homo sapiens 49-52 17371025-9 2007 For the SWNTs where N-R attaches to a parallel bond, the average shift of the sp2 carbons was found to be insensitive to the substituent R. Moreover, the shifts of the functionalized sp3 carbons, as well as of the carbons within the group itself, are independent of the SWNT radius. Carbon 82-89 Sp2 transcription factor Homo sapiens 78-81 17371025-9 2007 For the SWNTs where N-R attaches to a parallel bond, the average shift of the sp2 carbons was found to be insensitive to the substituent R. Moreover, the shifts of the functionalized sp3 carbons, as well as of the carbons within the group itself, are independent of the SWNT radius. Carbon 187-194 Sp3 transcription factor Homo sapiens 183-186 17371025-9 2007 For the SWNTs where N-R attaches to a parallel bond, the average shift of the sp2 carbons was found to be insensitive to the substituent R. Moreover, the shifts of the functionalized sp3 carbons, as well as of the carbons within the group itself, are independent of the SWNT radius. Carbon 187-194 Sp3 transcription factor Homo sapiens 183-186 17372346-1 2007 Catabolite control protein A (CcpA) functions as master transcriptional regulator of carbon catabolism in Firmicutes. Carbon 85-91 ccpA Lactococcus lactis subsp. lactis Il1403 30-34 17412899-9 2007 Carbon limitation in the cropping system may have led to microbial respiration using primarily O2 and to a lesser degree NO3. Carbon 0-6 NBL1, DAN family BMP antagonist Homo sapiens 121-124 17430050-4 2007 In addition, the uniqueness of the zigzag-edged graphene nanoribbon is further demonstrated by comparing it with other forms of sp2 carbons, including a graphene sheet, nanotubes, and an armchair-edged graphene nanoribbon. Carbon 132-139 Sp2 transcription factor Homo sapiens 128-131 17389467-8 2007 There were significant improvements in TG (P=0.009), TC (P=0.0001), LDL-c (P=0.019) and TC/HDL-c ratio (P=0.001), and a similar trend in HDL-c levels (P=0.069). Carbon 18-19 component of oligomeric golgi complex 2 Homo sapiens 68-73 17218092-1 2007 The crystal structure of the ligand binding domain (LBD) of the wild-type Vitamin D receptor (VDR) of zebrafish bound to Gemini, a synthetic agonist ligand with two identical side chains branching at carbon 20 reveals a ligand-dependent structural rearrangement of the ligand binding pocket (LBP). Carbon 200-206 vitamin D receptor a Danio rerio 74-92 17081619-8 2007 Poly I:C and CpG-ODN, but not imiquimod, induced significant levels of RANTES at different time-points post-treatment. Carbon 7-8 chemokine (C-C motif) ligand 5 Mus musculus 71-77 17174970-0 2007 The adsorption-desorption process of bovine serum albumin on carbon nanotubes. Carbon 61-67 albumin Homo sapiens 44-57 17174970-1 2007 The aim of this work is to study the adsorption-desorption process of bovine serum albumin (BSA) on carbon nanotubes (CNT) by reflectometry. Carbon 100-106 albumin Homo sapiens 77-90 16920014-7 2007 OLE1 is regulated through Spt23p and Mga2p by multiple systems that control its transcription and mRNA stability in response to diverse stimuli that include nutrient fatty acids, carbon source, metal ions and the availability of oxygen. Carbon 179-185 Spt23p Saccharomyces cerevisiae S288C 26-32 17338566-1 2007 A synthesis of ethene and ethyne derivatives carrying the anionic -C(BCH3)11- substituent on one or both carbon atoms is described. Carbon 105-111 chimerin 2 Homo sapiens 69-72 17388277-4 2007 The major loss of NO3 is adsorption on gray and black soot at yields of 65 and 59%, respectively, and the main gas-phase reaction product is N2O5 owing to heterogeneous recombination of NO3 with NO2 and NO according to NO3 + {C} --> NO + products. Carbon 226-227 NBL1, DAN family BMP antagonist Homo sapiens 18-21 17388277-4 2007 The major loss of NO3 is adsorption on gray and black soot at yields of 65 and 59%, respectively, and the main gas-phase reaction product is N2O5 owing to heterogeneous recombination of NO3 with NO2 and NO according to NO3 + {C} --> NO + products. Carbon 226-227 NBL1, DAN family BMP antagonist Homo sapiens 186-189 17388277-4 2007 The major loss of NO3 is adsorption on gray and black soot at yields of 65 and 59%, respectively, and the main gas-phase reaction product is N2O5 owing to heterogeneous recombination of NO3 with NO2 and NO according to NO3 + {C} --> NO + products. Carbon 226-227 NBL1, DAN family BMP antagonist Homo sapiens 186-189 17218092-1 2007 The crystal structure of the ligand binding domain (LBD) of the wild-type Vitamin D receptor (VDR) of zebrafish bound to Gemini, a synthetic agonist ligand with two identical side chains branching at carbon 20 reveals a ligand-dependent structural rearrangement of the ligand binding pocket (LBP). Carbon 200-206 vitamin D receptor a Danio rerio 94-97 17277890-1 2007 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12), a key enzyme of carbon metabolism, was purified and characterized to homogeneity from skeletal muscle of Camelus dromedarius. Carbon 80-86 glyceraldehyde-3-phosphate dehydrogenase Camelus dromedarius 0-40 17253801-0 2007 Regioselective oxyfunctionalization of unactivated carbons in steroids by a model of cytochrome P-450: osmiumporphyrin complex/tert-butyl hydroperoxide system. Carbon 51-58 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 85-101 17277890-1 2007 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12), a key enzyme of carbon metabolism, was purified and characterized to homogeneity from skeletal muscle of Camelus dromedarius. Carbon 80-86 glyceraldehyde-3-phosphate dehydrogenase Camelus dromedarius 42-47 17166647-1 2007 Cyclic voltammetry was used for simultaneous formation and immobilization of nickel oxide nano-scale islands and catalase on glassy carbon electrode. Carbon 132-138 catalase Homo sapiens 113-121 17103136-12 2007 The annual forest carbon sink in this region is estimated to be 76 Tg C/year, which would amount to an expenditure of $11.1-13.9 billion/year. Carbon 18-24 transglutaminase 2 Homo sapiens 67-71 17103136-13 2007 Best management practices could enhance carbon sequestration by 53.9 Tg C/year, accounting for 9.3% of current total annual regional greenhouse gas emission in the next 20 years. Carbon 40-46 transglutaminase 2 Homo sapiens 69-73 17103136-14 2007 Annual carbon storage in housing, furniture, and other wood products in 1998 was estimated to be 13.9 Tg C in the region. Carbon 7-13 transglutaminase 2 Homo sapiens 102-106 17186224-0 2007 An amperometric acetylthiocholine sensor based on immobilization of acetylcholinesterase on a multiwall carbon nanotube-cross-linked chitosan composite. Carbon 104-110 acetylcholinesterase (Cartwright blood group) Homo sapiens 68-88 17186224-1 2007 A simple method has been devised for immobilization of acetylcholinesterase (AChE)--covalent bonding to a multiwall carbon nanotube (MWNT)--cross-linked chitosan composite (CMC)-and a sensitive amperometric sensor for rapid detection of acetylthiocholine (ATCl) has been based on this. Carbon 116-122 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-75 17186224-1 2007 A simple method has been devised for immobilization of acetylcholinesterase (AChE)--covalent bonding to a multiwall carbon nanotube (MWNT)--cross-linked chitosan composite (CMC)-and a sensitive amperometric sensor for rapid detection of acetylthiocholine (ATCl) has been based on this. Carbon 116-122 acetylcholinesterase (Cartwright blood group) Homo sapiens 77-81 17166647-9 2007 The resultant catalase/nickel oxide modified glassy carbon electrodes exhibited fast amperometric response (within 2 s) to hydrogen peroxide reduction (with a linear range from 1 microM to 1 mM), excellent stability, long term life and good reproducibility. Carbon 52-58 catalase Homo sapiens 14-22 17222052-1 2007 We have fabricated label-free protein biosensors based on aptamer-modified carbon nanotube field-effect transistors (CNT-FETs) for the detection of immunoglobulin E (IgE). Carbon 75-81 immunoglobulin heavy constant epsilon Homo sapiens 166-169 16624546-2 2007 The composite film was used to immobilize PPO on the surface of a glassy carbon electrode. Carbon 73-79 protoporphyrinogen oxidase Homo sapiens 42-45 17226958-15 2007 However, when a three-carbon bridge was used to attach PEG, our PEG-IFN"s biological activity was found to be independent of the length of the PEG. Carbon 22-28 interferon alpha 1 Homo sapiens 68-71 19071279-1 2007 In this work, 1,10-phenanthroline was used as a complexing agent for the separation and preconcentration of Cd(II), Co(II), Ni(II), Cu(II) and Pb(II) on activated carbon. Carbon 163-169 mitochondrially encoded cytochrome c oxidase II Homo sapiens 116-122 19071279-1 2007 In this work, 1,10-phenanthroline was used as a complexing agent for the separation and preconcentration of Cd(II), Co(II), Ni(II), Cu(II) and Pb(II) on activated carbon. Carbon 163-169 submaxillary gland androgen regulated protein 3B Homo sapiens 143-149 17386417-0 2007 Electrocatalytic detection of insulin at RuOx/carbon nanotube-modified carbon electrodes. Carbon 46-52 insulin Homo sapiens 30-37 17386417-0 2007 Electrocatalytic detection of insulin at RuOx/carbon nanotube-modified carbon electrodes. Carbon 71-77 insulin Homo sapiens 30-37 17386417-1 2007 A bilayer surface coating, prepared by electrodepositing ruthenium oxide (RuOx) onto a carbon nanotube (CNT) layer, offers dramatic improvements in the stability and sensitivity of voltammetric and amperometric measurements of insulin compared to the individual (CNT or RuOx) coated electrodes. Carbon 87-93 insulin Homo sapiens 227-234 17659663-1 2007 We report that only elements more electropositive than carbon (Group 13, 14, and Be) form stable symmetrical HnE--CH3--EHn + structures (E=Group 1, 2, 13, or 14 element) with a planar CH3 group symmetrically bonded to two EHn moieties, in analogy with prototypical SN2 transition structures. Carbon 55-61 solute carrier family 38 member 5 Homo sapiens 265-268 17728299-9 2007 In kat2-1 ovules, carbon flow into sugars via gluconeogeneis and respiration were both reduced in comparison to the wild type. Carbon 18-24 potassium channel KAT1-like protein Arabidopsis thaliana 3-7 17009371-0 2007 G2(+) investigation on the alpha-effect in the SN2 reactions at saturated carbon. Carbon 74-80 solute carrier family 38 member 5 Homo sapiens 47-50 16890925-2 2007 CETP gene is known to have many single nucleotide polymorphisms which have been associated with CETP activity and plasma high density lipoprotein cholesterol (HDL-C) concentrations. Carbon 162-164 cholesteryl ester transfer protein Homo sapiens 0-4 17089339-1 2007 A new doubly tethered chiral stationary phase (CSP 5) based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid was developed by attaching the second tethering group to silica gel through a carbon atom of the first tethering group of the corresponding singly tethered CSP (CSP 2) containing an N-CH3 tertiary amide linkage, which was previously developed in our laboratory, in order to enhance the CSP stability without the loss of chiral recognition efficiency. Carbon 189-195 DnaJ heat shock protein family (Hsp40) member C5 Homo sapiens 47-50 17578866-8 2007 The AtNRT2.1 high-affinity nitrate transporter seems to be involved in the repression of lateral root initiation by high C:N ratios. Carbon 121-122 nitrate transporter 2:1 Arabidopsis thaliana 4-12 17426136-4 2007 To reveal the molecular basis of poly(C)-sequence recognition, we have determined the crystal structure, at 1.6 A resolution, of PCBP2 KH3 domain in complex with a 7-nt DNA sequence (5"-AACCCTA-3") corresponding to one repeat of the C-rich strand of human telomeric DNA. Carbon 38-39 poly(rC) binding protein 2 Homo sapiens 129-134 17182588-4 2007 A robust eosinophil chemotactic activity was released from BSMC stimulated with poly(I:C) and IL-4, which was mostly inhibited by preincubation with an anti-CCL11, but not with an anti-CCL5 Ab. Carbon 62-63 interleukin 4 Homo sapiens 94-98 17182588-4 2007 A robust eosinophil chemotactic activity was released from BSMC stimulated with poly(I:C) and IL-4, which was mostly inhibited by preincubation with an anti-CCL11, but not with an anti-CCL5 Ab. Carbon 62-63 C-C motif chemokine ligand 11 Homo sapiens 157-162 17179734-0 2007 Prospective randomized study evaluating the efficacy of the spherical adsorptive carbon AST-120 in chronic kidney disease patients with moderate decrease in renal function. Carbon 81-87 solute carrier family 17 member 5 Homo sapiens 88-91 17179734-1 2007 AIMS: We studied whether adding the spherical adsorptive carbon AST-120 to conventional treatments is effective in inhibiting progression of chronic kidney disease (CKD) at the stage of moderate decrease in renal function. Carbon 57-63 solute carrier family 17 member 5 Homo sapiens 64-67 16839769-1 2007 The production of a higher-order assembly of peroxiredoxin-2 (Prx-2) from human erythrocytes has been achieved during specimen preparation on holey carbon support films, in the presence of ammonium molybdate and polyethylene glycol. Carbon 148-154 peroxiredoxin 2 Homo sapiens 45-60 16839769-1 2007 The production of a higher-order assembly of peroxiredoxin-2 (Prx-2) from human erythrocytes has been achieved during specimen preparation on holey carbon support films, in the presence of ammonium molybdate and polyethylene glycol. Carbon 148-154 peroxiredoxin 2 Homo sapiens 62-67 17546977-5 2007 On average, 10 g total (t) COD/g NO3-N were required in the pre-DN stage for denitrification in the pilot and full-scale plant and 0.4-0.5 kg NO3-N/(m(3)DN d) can be reached without external carbon. Carbon 191-197 NBL1, DAN family BMP antagonist Homo sapiens 33-36 17639569-0 2007 Wavelength-dependent Coulomb explosion in carbon disulphide (CS2) clusters: generation of energetic multiply charged carbon and sulphur ions. Carbon 42-48 chorionic somatomammotropin hormone 2 Homo sapiens 61-64 17147366-4 2006 Products bear all-carbon quaternary sterogenic centers generated in 3.5-13.3:1 regioselectivity, 63-98% ee, and in up to 80% isolated yield of the SN2" product. Carbon 18-24 solute carrier family 38 member 5 Homo sapiens 147-150 17177441-5 2006 For wild-type FAAH, the results support a mechanism, which features proton transfer from Ser217 to Lys142, simultaneous proton transfer from Ser241 to Ser217, and attack of Ser241 on the substrate"s carbonyl carbon to yield a tetrahedral intermediate, which subsequently undergoes elimination with simultaneous protonation of the leaving group by a Lys142-Ser217 proton shuttle. Carbon 199-205 fatty acid amide hydrolase Homo sapiens 14-18 16896794-5 2006 Sugars, sugar phosphates, alcohols, pyruvate, and many other organic acids accumulated in sse1 seeds as a likely consequence of the reduced carbon demand for lipid synthesis. Carbon 140-146 shrunken seed protein (SSE1) Arabidopsis thaliana 90-94 16904332-1 2006 The nature of C-5 substituent and the configuration at C-5 carbon of 2,3-diphenyltetrahydrofurans, with chiral centres at C-2, C-3 and C-5, show a remarkable influence on their COX-2 inhibition and selectivity. Carbon 59-65 mitochondrially encoded cytochrome c oxidase II Homo sapiens 177-182 16914195-5 2006 The synthesized carbons, having tunable pore size with a large volume of slit-shaped mesopores, outperformed all other materials or methods in terms of efficiency of TNF-alpha removal and the results are comparable only with highly specific antibody-antigen interactions. Carbon 16-23 tumor necrosis factor Homo sapiens 166-175 17007826-6 2006 In addition, C-ANP4-23 also inhibited protein synthesis stimulated by AngII, ET-1 and AVP; whereas basal protein synthesis in these cells was not inhibited by C-ANP4-23 or by the peptide fragments. Carbon 13-14 angiotensinogen Homo sapiens 70-75 17007826-6 2006 In addition, C-ANP4-23 also inhibited protein synthesis stimulated by AngII, ET-1 and AVP; whereas basal protein synthesis in these cells was not inhibited by C-ANP4-23 or by the peptide fragments. Carbon 13-14 endothelin 1 Homo sapiens 77-89 17027152-2 2006 A polymorphism consisting of a single nucleotide (C-->T) change at position 609 of NQO1 influences the NQO1 activity. Carbon 50-53 NAD(P)H quinone dehydrogenase 1 Homo sapiens 83-87 17027152-2 2006 A polymorphism consisting of a single nucleotide (C-->T) change at position 609 of NQO1 influences the NQO1 activity. Carbon 50-53 NAD(P)H quinone dehydrogenase 1 Homo sapiens 103-107 16896794-8 2006 To convert the excess carbon metabolites into starch, we introduced the Escherichia coli starch synthetic enzyme ADP-glucose pyrophosphorylase (AGPase) into sse1 seeds. Carbon 22-28 shrunken seed protein (SSE1) Arabidopsis thaliana 157-161 16935321-5 2006 A statistically significant relationship between dry weight soil concentrations and organic carbon content was determined for all PCB congeners in the surface layers (0-1 cm) but not in the deeper layers (4-5 cm, 9-10 cm). Carbon 92-98 pyruvate carboxylase Homo sapiens 130-133 17125399-4 2006 The PES of these supermolecules is fit to an (exp-6) function whose variables are subsequently used to derive a mass-centered potential energy function as a function of the number of carbon atoms in the supermolecule. Carbon 183-189 exportin 6 Homo sapiens 46-51 17067544-3 2006 The greater part of the hydroperoxy derivative was found to contain hydroperoxide group at C-13 rather than C-9, consistent with the position specificity of soybean lipoxygenase-1 in oxygenation of linoleic acid. Carbon 91-92 seed linoleate 13S-lipoxygenase-1 Glycine max 165-179 16920127-2 2006 In this procedure, long-chain fatty acids (C(14), C(16) and C(18)) were converted into their ion-pair complexes with tetrabutylammonium hydrogen sulfate and then extracted by organic solvent (1-octanol) impregnated in the hollow fiber. Carbon 43-44 Bardet-Biedl syndrome 9 Homo sapiens 60-65 17015690-4 2006 In addition, a PPARgamma agonist that is a structural analog of 15d-PGJ2, and lacks the electrophilic carbon of the 15d-PGJ2 cyclopentenone ring, activated PPARgamma but did not kill B lymphocytes, further supporting a non-PPARgamma-mediated mechanism. Carbon 102-108 peroxisome proliferator activated receptor gamma Homo sapiens 15-24 16682066-2 2006 This paper presents a novel process integrated electrocatalysis and activated carbon (AC) adsorption in a fluidization mode for p-nitrophenol (PNP) abatement, with special attention on probing the role of AC. Carbon 78-84 purine nucleoside phosphorylase Homo sapiens 143-146 17252798-1 2006 We have developed a biosensor capable of detecting carcinoembryonic antigen (CEA) markers using single-walled carbon nanotube field effect transistors (SWNT-FETs). Carbon 110-116 CEA cell adhesion molecule 3 Homo sapiens 51-75 17252798-1 2006 We have developed a biosensor capable of detecting carcinoembryonic antigen (CEA) markers using single-walled carbon nanotube field effect transistors (SWNT-FETs). Carbon 110-116 CEA cell adhesion molecule 3 Homo sapiens 77-80 17252798-4 2006 CEA antibodies were employed as recognition elements to specific tumor markers, and were successfully immobilized on the sides of a single-walled carbon nanotube using CDI-Tween 20 linking molecules. Carbon 146-152 CEA cell adhesion molecule 3 Homo sapiens 0-3 17723752-4 2006 In an indicative application, Pb(II) ion levels were determined in tap water using bismuth-plated carbon microdisc electrodes. Carbon 98-104 submaxillary gland androgen regulated protein 3B Homo sapiens 30-36 17015690-4 2006 In addition, a PPARgamma agonist that is a structural analog of 15d-PGJ2, and lacks the electrophilic carbon of the 15d-PGJ2 cyclopentenone ring, activated PPARgamma but did not kill B lymphocytes, further supporting a non-PPARgamma-mediated mechanism. Carbon 102-108 peroxisome proliferator activated receptor gamma Homo sapiens 156-165 17015690-4 2006 In addition, a PPARgamma agonist that is a structural analog of 15d-PGJ2, and lacks the electrophilic carbon of the 15d-PGJ2 cyclopentenone ring, activated PPARgamma but did not kill B lymphocytes, further supporting a non-PPARgamma-mediated mechanism. Carbon 102-108 peroxisome proliferator activated receptor gamma Homo sapiens 156-165 16871508-2 2006 Complex 1 a reacts under the same conditions with H(2)C=C=CHMgBr to afford fac-[MnI(CO)(3){(PPh(2))(2)C=C(CH(2)CC[triple chemical bond]CH)NHR}] (5 a), which contains a terminal alkyne group on the alpha-carbon atom of the diphosphinoenamine ligand. Carbon 0-1 FA complementation group C Homo sapiens 75-78 16962138-1 2006 The C-11=C-12 double bond of the retinylidene chromophore of rhodopsin holds a central position in its light-induced photoisomerization and hence the photosensory function of this visual pigment. Carbon 4-5 rhodopsin Homo sapiens 61-70 16962138-1 2006 The C-11=C-12 double bond of the retinylidene chromophore of rhodopsin holds a central position in its light-induced photoisomerization and hence the photosensory function of this visual pigment. Carbon 9-10 rhodopsin Homo sapiens 61-70 16962138-2 2006 To probe the local environment of the HC-11=C-12H element we have prepared the 11-methyl and 12-methyl derivatives of 11-Z retinal and incorporated these into opsin to generate the rhodopsin analogs 11-methyl and 12-methyl rhodopsin. Carbon 39-40 rhodopsin Homo sapiens 181-190 16871508-2 2006 Complex 1 a reacts under the same conditions with H(2)C=C=CHMgBr to afford fac-[MnI(CO)(3){(PPh(2))(2)C=C(CH(2)CC[triple chemical bond]CH)NHR}] (5 a), which contains a terminal alkyne group on the alpha-carbon atom of the diphosphinoenamine ligand. Carbon 54-55 FA complementation group C Homo sapiens 75-78 16871508-2 2006 Complex 1 a reacts under the same conditions with H(2)C=C=CHMgBr to afford fac-[MnI(CO)(3){(PPh(2))(2)C=C(CH(2)CC[triple chemical bond]CH)NHR}] (5 a), which contains a terminal alkyne group on the alpha-carbon atom of the diphosphinoenamine ligand. Carbon 203-209 FA complementation group C Homo sapiens 75-78 17051780-0 2006 Nanometer-scale chemical heterogeneities of black carbon materials and their impacts on PCB sorption properties: soft X-ray spectromicroscopy study. Carbon 50-56 pyruvate carboxylase Homo sapiens 88-91 16806458-3 2006 Results indicate that a number of the primary carbon/resin materials demonstrate efficient adsorption of the cytokines studied here (TNF, IL-6 and IL-8), comparable to other adsorbents under clinical investigation. Carbon 46-52 tumor necrosis factor Homo sapiens 133-136 16806458-3 2006 Results indicate that a number of the primary carbon/resin materials demonstrate efficient adsorption of the cytokines studied here (TNF, IL-6 and IL-8), comparable to other adsorbents under clinical investigation. Carbon 46-52 interleukin 6 Homo sapiens 138-142 16806458-3 2006 Results indicate that a number of the primary carbon/resin materials demonstrate efficient adsorption of the cytokines studied here (TNF, IL-6 and IL-8), comparable to other adsorbents under clinical investigation. Carbon 46-52 C-X-C motif chemokine ligand 8 Homo sapiens 147-151 16630644-3 2006 We examined the chemical reactivity of AC-supported iron as a catalyst to decompose PCB-153, and varied three decomposition parameters (temperature, time and iron concentration) under an atmosphere of either air or N(2). Carbon 39-41 pyruvate carboxylase Homo sapiens 84-87 17022395-4 2006 The concentrations of seven PCB congeners were determined in the dissolved and particulate organic carbon (POC) phases. Carbon 99-105 pyruvate carboxylase Homo sapiens 28-31 16970972-1 2006 The efficiency of Co(II)-, Mn(II)-, and Ti(IV)-doped carbon aerogels for the transformation of ozone into (*)OH radicals was investigated. Carbon 53-59 mitochondrially encoded cytochrome c oxidase II Homo sapiens 18-25 16905358-5 2006 One gene, Nar1.2, was strongly carbon-regulated independently of Nit2; two genes, Nar1.1 and Nar1.6, were regulated by nitrogen and Nit2; and the other genes, Nar1.3, Nar1.4, and Nar1.5 were independent of Nit2 and responded to nitrogen or carbon treatments in a transient and not easily understandable way. Carbon 31-37 uncharacterized protein Chlamydomonas reinhardtii 10-16 16867988-8 2006 A catalytic mechanism of POR is suggested in which Pchlide absorbs a photon, creating a transient charge separation across the C-17-C-18 double bond, which promotes ultrafast hydride transfer from the pro-S face of NADPH to the C-17 of Pchlide. Carbon 127-128 cytochrome p450 oxidoreductase Homo sapiens 25-28 16857669-2 2006 Aor was further characterized as an Nrf2-regulated antioxidative enzyme that reduces carbon-carbon double bonds in a variety of alpha, beta-unsaturated aldehydes and ketones. Carbon 85-91 NFE2 like bZIP transcription factor 2 Rattus norvegicus 36-40 16698029-5 2006 In contrast, the C18 Aqua column, having the highest surface coverage (15% carbon load) was found to have the second lowest molecular-stationary phase interactions (rate of change in S=0.61). Carbon 75-81 Bardet-Biedl syndrome 9 Homo sapiens 17-20 16857669-2 2006 Aor was further characterized as an Nrf2-regulated antioxidative enzyme that reduces carbon-carbon double bonds in a variety of alpha, beta-unsaturated aldehydes and ketones. Carbon 92-98 NFE2 like bZIP transcription factor 2 Rattus norvegicus 36-40 16939289-0 2006 Control of sp2/sp3 carbon ratio and surface chemistry of nanodiamond powders by selective oxidation in air. Carbon 19-25 Sp3 transcription factor Homo sapiens 15-18 17072036-8 2006 We found that the SA patients had the highest level of ET-1 (SA - 11.4 +/-3.6 fmol/ml; AA - 7.1 +/-2.7 fmol/ml; C - 5.6 +/-1.8 fmol/ml) in BALF. Carbon 112-113 endothelin 1 Homo sapiens 55-59 16914311-9 2006 Central to these new renditions is the hypothesis that the appropriate P-450 introduces dioxygen into the precursor yielding either: A, a 20 peroxy sterol species or B, a species oxygenated at both C-17 and C-20 or C, a species oxygenated at both C-20 and C-21. Carbon 0-1 TBL1X/Y related 1 Homo sapiens 256-260 16937818-8 2006 Vegetation in European forests is modeled to sequester carbon at a rate of 100 Tg C/yr, which corresponds well to forest inventory-based estimates. Carbon 55-61 transglutaminase 2 Homo sapiens 79-83 16913860-7 2006 These data suggest that a key element in recovering flux through carbohydrate metabolism in the cold is to control the partitioning of metabolites between the chloroplast and the cytosol, and Arabidopsis modulates the expression of AtTPT to maintain balanced carbon flow. Carbon 259-265 Glucose-6-phosphate/phosphate translocator-like protein Arabidopsis thaliana 232-237 16931295-0 2006 Amperometric detection of insulin at renewable sol-gel derived carbon ceramic electrode modified with nickel powder and potassium octacyanomolybdate(IV). Carbon 63-69 insulin Homo sapiens 26-33 16855586-1 2006 Graphene sheets--one-atom-thick two-dimensional layers of sp2-bonded carbon--are predicted to have a range of unusual properties. Carbon 69-75 Sp2 transcription factor Homo sapiens 58-61 16883455-12 2006 The most common microorganisms isolated from C/S is Group A beta hemolytic streptococcus (17/81 [21%]). Carbon 45-46 amyloid beta precursor protein Homo sapiens 58-64 16941994-6 2006 The maximum carbon conversion of 14.54% was obtained when the percentage of seeding was set at 14.5%, the air suction rate was set at 2.6 L kg(-1) dry-solid min(-1), and the agitator operated half of the time, alternating on and off for every 5 min. Carbon 12-18 CD59 molecule (CD59 blood group) Homo sapiens 157-163 16850348-9 2006 While the Thi2, in conjunction with Thi3, seems to control expression of THI genes with respect to thiamine availability, the Pdc2 may link the ThDP demand to carbon source availability. Carbon 159-165 Pdc2p Saccharomyces cerevisiae S288C 126-130 16627483-3 2006 FDH has been proposed to: 1) inhibit purine biosynthesis by depleting 10-formyl-THF pools, 2) maintain cellular folate concentrations by sequestering THF, 3) deplete the supply of folate-activated one-carbon units, and 4) stimulate the generation of THF-activated one-carbon unit synthesis by channeling folate cofactors to other folate-dependent enzymes. Carbon 201-207 aldehyde dehydrogenase 1 family member L1 Homo sapiens 0-3 16627483-3 2006 FDH has been proposed to: 1) inhibit purine biosynthesis by depleting 10-formyl-THF pools, 2) maintain cellular folate concentrations by sequestering THF, 3) deplete the supply of folate-activated one-carbon units, and 4) stimulate the generation of THF-activated one-carbon unit synthesis by channeling folate cofactors to other folate-dependent enzymes. Carbon 268-274 aldehyde dehydrogenase 1 family member L1 Homo sapiens 0-3 16627483-2 2006 Although several activities have been ascribed to FDH, its metabolic role in folate-mediated one-carbon metabolism is not well understood. Carbon 97-103 aldehyde dehydrogenase 1 family member L1 Homo sapiens 50-53 16627483-8 2006 We conclude that low FDH expression facilitates the incorporation of one-carbon units into the one-carbon pool, whereas high levels of FDH expression deplete the folate-activated one-carbon pool by catalyzing the conversion of 10-formyl-THF to THF. Carbon 73-79 aldehyde dehydrogenase 1 family member L1 Homo sapiens 21-24 16698903-8 2006 These studies offer insight into the molecular level regulation of SUS1 localization and its participation in carbon partitioning in plants. Carbon 110-116 sucrose synthase 2 Zea mays 67-71 16856737-1 2006 The sorption kinetics and concentration of polychlorinated biphenyls (PCBs) in historically polluted sediment is modeled to assess a remediation strategy based on in situ PCB sequestration by mixing with activated carbon (AC). Carbon 214-220 pyruvate carboxylase Homo sapiens 70-73 16556766-3 2006 In the pancreatic beta-cell, glucose carbons are quantitatively funneled to the mitochondria, where signals for the initiation and potentiation of insulin secretion are generated. Carbon 37-44 insulin Homo sapiens 147-154 16910042-0 2006 Determination of catalase-like activity in plants based on the amperometric monitoring of hydrogen peroxide consumption using a carbon paste electrode modified with ruthenium(IV) Oxide. Carbon 128-134 catalase Homo sapiens 17-25 16800480-5 2006 19F magic angle spinning (MAS) NMR, 13C MAS NMR, and 13C MAS NMR with 19F to 13C cross polarization (CP) underline the presence of two types of carbon atoms, both sp3 hybridized: some covalently bonded to fluorine and the others linked exclusively to carbon atoms. Carbon 144-150 Sp3 transcription factor Homo sapiens 163-166 16800483-0 2006 Formation of porous carbon materials with in situ generated NaF nanotemplate. Carbon 20-26 C-X-C motif chemokine ligand 8 Homo sapiens 60-63 16800483-1 2006 Porous carbon materials with pore sizes from 3 to 200 nm were synthesized by reacting hexafluorobenzene with Na liquid at 623 K. NaF crystals, a byproduct formed in the reaction, acted as nanotemplate to assist the pore formation. Carbon 7-13 C-X-C motif chemokine ligand 8 Homo sapiens 129-132 16739131-10 2006 Increased levels of cystatin C and beta-2-microglobulin in conditioned media from p21-expressing cells was confirmed by antibody capture experiments using anticystatin C and anti-beta-2-microglobulin antibodies on preactivated PS-20 arrays. Carbon 29-30 cyclin dependent kinase inhibitor 1A Homo sapiens 82-85 16055167-8 2006 An increase in dissolved organic carbon content promoted both As(V) and As(III) solubilization in soils. Carbon 33-39 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 62-67 16771503-6 2006 We provide evidence that the formation of the Gly96 radical, which promotes the oxidative protein scission and the subsequent chromophore release, is the major pathway for the self-decomposition of C-1027. Carbon 198-199 immediate early response 3 Homo sapiens 46-51 16734451-0 2006 Electrochemical performance of angstrom level flat sputtered carbon film consisting of sp2 and sp3 mixed bonds. Carbon 61-67 Sp2 transcription factor Homo sapiens 87-90 16734451-0 2006 Electrochemical performance of angstrom level flat sputtered carbon film consisting of sp2 and sp3 mixed bonds. Carbon 61-67 Sp3 transcription factor Homo sapiens 95-98 16688324-1 2006 The synthesis and characterisation of the cyclobutyl complex Tp(Me2)NbCl(c-C4H7)(MeC[triple bond]CMe) completes the family of cycloalkyl complexes Tp(Me2)NbCl(c-C(n)H(2n-1)), n = 3-6. Carbon 23-24 malic enzyme 2 Homo sapiens 64-67 16688324-1 2006 The synthesis and characterisation of the cyclobutyl complex Tp(Me2)NbCl(c-C4H7)(MeC[triple bond]CMe) completes the family of cycloalkyl complexes Tp(Me2)NbCl(c-C(n)H(2n-1)), n = 3-6. Carbon 18-19 malic enzyme 2 Homo sapiens 64-67 16688324-1 2006 The synthesis and characterisation of the cyclobutyl complex Tp(Me2)NbCl(c-C4H7)(MeC[triple bond]CMe) completes the family of cycloalkyl complexes Tp(Me2)NbCl(c-C(n)H(2n-1)), n = 3-6. Carbon 18-19 C-C motif chemokine ligand 28 Homo sapiens 81-84 16688324-1 2006 The synthesis and characterisation of the cyclobutyl complex Tp(Me2)NbCl(c-C4H7)(MeC[triple bond]CMe) completes the family of cycloalkyl complexes Tp(Me2)NbCl(c-C(n)H(2n-1)), n = 3-6. Carbon 23-24 C-C motif chemokine ligand 28 Homo sapiens 81-84 16688324-1 2006 The synthesis and characterisation of the cyclobutyl complex Tp(Me2)NbCl(c-C4H7)(MeC[triple bond]CMe) completes the family of cycloalkyl complexes Tp(Me2)NbCl(c-C(n)H(2n-1)), n = 3-6. Carbon 18-19 malic enzyme 2 Homo sapiens 150-153 16688324-1 2006 The synthesis and characterisation of the cyclobutyl complex Tp(Me2)NbCl(c-C4H7)(MeC[triple bond]CMe) completes the family of cycloalkyl complexes Tp(Me2)NbCl(c-C(n)H(2n-1)), n = 3-6. Carbon 23-24 malic enzyme 2 Homo sapiens 150-153 16516473-1 2006 The structure-activity relationship of a novel subseries of 4-anilinoquinazoline EGFR inhibitors substituted at the C-6 position with carbon-linked side chains has been investigated. Carbon 134-140 epidermal growth factor receptor Homo sapiens 81-85 16649777-7 2006 Application of either positive or negative dc electrical bias affects the carbon core-level (C1s) line shape and intensity, which is dependent on the atom"s physical location above the surface. Carbon 74-80 complement C1s Homo sapiens 93-96 16289193-5 2006 Sorption data with BTEA organoclay and TNT were fit to Langmuir isotherms; however, the clay"s sorptive capacity increased as the amount of total organic carbon sorbed to the clay"s surface was decreased. Carbon 154-160 chromosome 16 open reading frame 82 Homo sapiens 39-42 16575899-11 2006 Taking into consideration that in the one-carbon metabolism cystathionine beta-synthase (CBS) catalyzes Hcy in an irreversible way, and that CBS gene is located in chromosome 21, fetuses and infants with DS have functional folate deficiency due to overexpression of CBS. Carbon 42-48 cystathionine beta-synthase Homo sapiens 60-87 16575899-11 2006 Taking into consideration that in the one-carbon metabolism cystathionine beta-synthase (CBS) catalyzes Hcy in an irreversible way, and that CBS gene is located in chromosome 21, fetuses and infants with DS have functional folate deficiency due to overexpression of CBS. Carbon 42-48 cystathionine beta-synthase Homo sapiens 89-92 16546711-5 2006 The results demonstrated that Con A pretreatment aggravated poly I:C-induced liver injury with elevation of serum transaminases, hepatic necrosis and serum IFN-gamma level. Carbon 30-31 interferon gamma Mus musculus 156-165 16649792-5 2006 The C-H...F hydrogen bonding between the ortho carbon of the phenyl ring and the fluorine of the BF2 group plays an important role in the formation of the adlayers. Carbon 47-53 forkhead box G1 Homo sapiens 97-100 16289193-6 2006 Sorption behavior for TNT reduction products 2-A-4,6-DNT and 4-A-2,6-DNT to one HDTMA organoclay and one BTEA organoclay demonstrated that HDTMA organoclay at 10.3% total organic carbon was a more effective sorbent than BTEA organoclay at 5.2% total organic carbon. Carbon 179-185 chromosome 16 open reading frame 82 Homo sapiens 22-25 16289193-6 2006 Sorption behavior for TNT reduction products 2-A-4,6-DNT and 4-A-2,6-DNT to one HDTMA organoclay and one BTEA organoclay demonstrated that HDTMA organoclay at 10.3% total organic carbon was a more effective sorbent than BTEA organoclay at 5.2% total organic carbon. Carbon 258-264 chromosome 16 open reading frame 82 Homo sapiens 22-25 16397765-5 2006 We demonstrated that HXT5, HXT13 and, to a lesser extent, HXT15 were all induced in the presence of non-fermentable carbon sources. Carbon 116-122 hexose transporter HXT15 Saccharomyces cerevisiae S288C 58-63 16715386-4 2006 Furthermore, the T1rho of the insulin carbonyl carbon in the lyophilized insulin-dextran and insulin-trehalose systems was measured at 25 degrees C by 13C solid-state NMR, and the effect of trehalose and dextran on T1rho was compared at various humidities. Carbon 38-44 insulin Homo sapiens 30-37 16715386-4 2006 Furthermore, the T1rho of the insulin carbonyl carbon in the lyophilized insulin-dextran and insulin-trehalose systems was measured at 25 degrees C by 13C solid-state NMR, and the effect of trehalose and dextran on T1rho was compared at various humidities. Carbon 38-44 insulin Homo sapiens 73-80 16715386-4 2006 Furthermore, the T1rho of the insulin carbonyl carbon in the lyophilized insulin-dextran and insulin-trehalose systems was measured at 25 degrees C by 13C solid-state NMR, and the effect of trehalose and dextran on T1rho was compared at various humidities. Carbon 38-44 insulin Homo sapiens 73-80 16715386-8 2006 In addition, the T1rho of the insulin carbonyl carbon at low humidity (12% RH) was prolonged by the addition of trehalose, but not by the addition of dextran. Carbon 38-44 insulin Homo sapiens 30-37 16610787-6 2006 Transformation of the C=O functionality at position 4 into a C=S group provided 5,7-dihydroxy-3-(4-hydroxyphenyl)-4(3H)-quinazolinethione (1ba), which acts as an agonist on both ER subtypes but has 56-fold higher binding affinity for ERbeta over ERalpha [IC(50)(ERbeta) = 47 nM] and 215-fold higher potency in the transcription assay [EC(50)(ERbeta) = 13 nM]. Carbon 22-23 estrogen receptor 1 Homo sapiens 246-253 16505984-1 2006 A simple and highly selective electrochemical method for the simultaneous determination of CAT and HQ at a glassy carbon electrode in micellar solutions has been developed. Carbon 114-120 catalase Homo sapiens 91-94 16611019-8 2006 Among the categorized CYP3A4-mediated reactions, the best lipophilicity-kinetics correlation is achieved for carbon hydroxylation, followed by N-dealkylation. Carbon 109-115 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 22-28 16406095-7 2006 Histamine and poly (I:C), a specific TLR3 ligand stimulated interleukin (IL)-8 secretion from both cell types. Carbon 22-23 C-X-C motif chemokine ligand 8 Homo sapiens 60-78 16550506-4 2006 Differences in esterase activities between susceptible and resistant strains increased with increasing carbon number of the aliphatic side-chain of the nitrophenol substrate. Carbon 103-109 acetylcholinesterase-like Tetranychus urticae 15-23 16600577-0 2006 Human fibrinogen adsorption onto single-walled carbon nanotube films. Carbon 47-53 fibrinogen beta chain Homo sapiens 6-16 16600577-1 2006 The adsorption behavior of human fibrinogen (Hfg) on single-walled carbon nanotube (SWNT) films was investigated using scanning electron microscopy (SEM) and near edge X-ray absorption fine structure (NEXAFS) spectroscopy. Carbon 67-73 fibrinogen beta chain Homo sapiens 33-43 16453354-0 2006 Structural and magnetic studies of the tris(cyclopentadienyl)manganese(II) "paddle-wheel" anions [Cp(3-n)(MeCp)(n)Mn](-) (n=0-3, MeCp=C(5)H(4)CH(3), Cp=C(5)H(5)). Carbon 98-99 C-C motif chemokine ligand 28 Homo sapiens 106-110 16614893-3 2006 Anti-AFP-modified MNP (bio-nanoparticles) were then attached to the surface of carbon paste electrode with the aid of a permanent magnet. Carbon 79-85 alpha fetoprotein Homo sapiens 5-8 16402205-8 2006 These data suggest that the interaction between Fhl1p and Ifh1p is critical for the regulation of CPC2 transcription during utilization of different carbon sources. Carbon 149-155 Ifh1p Saccharomyces cerevisiae S288C 58-63 16533058-8 2006 Our findings demonstrate a unique cellular response to C-1027-induced DNA DSBs in that DNA damage response proteins are unaffected by the absence of ATM, as long as ATR is present. Carbon 55-56 ATR serine/threonine kinase Homo sapiens 165-168 26558584-4 2006 The production rate of carbon nanostructures including CNTs at 75 A is as high as 5.89 +- 0.28 g min(-1). Carbon 23-29 CD59 molecule (CD59 blood group) Homo sapiens 97-103 16537407-2 2006 We synthesized a series of antagonists of GHRH(1-29)NH(2) acylated at the N terminus with monocarboxylic or alpha,omega-dicarboxylic acids containing six to sixteen carbon atoms. Carbon 165-171 growth hormone releasing hormone Homo sapiens 42-46 16553903-6 2006 This spatiotemporal characterization of carbon metabolism has also been applied to various mutants disrupted in embryo development including gnom (gn), acetyl-CoA carboxylase1 (acc1), schlepperless (slp), and wrinkled1 (wri1). Carbon 40-46 chaperonin-60alpha Arabidopsis thaliana 199-202 16549782-7 2006 We also show that the published structures of the PP5 TPR domain and the TPR domain of p67, the Rac-binding subunit of NADPH oxidase, superimpose over 92 alpha carbons. Carbon 160-167 protein phosphatase 5, catalytic subunit Rattus norvegicus 50-53 16549782-7 2006 We also show that the published structures of the PP5 TPR domain and the TPR domain of p67, the Rac-binding subunit of NADPH oxidase, superimpose over 92 alpha carbons. Carbon 160-167 guanylate binding protein 2 Rattus norvegicus 87-90 16533058-4 2006 Like ionizing radiation (IR) and other radiomimetics, breaks induced by C-1027 efficiently activate ATM by phosphorylation at Ser1981, yet unlike other radiomimetics and IR, DNA breaks induced by C-1027 result in normal phosphorylation of p53 and the cell cycle checkpoint kinases (Chk1 and Chk2) in the absence of ATM. Carbon 72-73 tumor protein p53 Homo sapiens 239-242 16533058-4 2006 Like ionizing radiation (IR) and other radiomimetics, breaks induced by C-1027 efficiently activate ATM by phosphorylation at Ser1981, yet unlike other radiomimetics and IR, DNA breaks induced by C-1027 result in normal phosphorylation of p53 and the cell cycle checkpoint kinases (Chk1 and Chk2) in the absence of ATM. Carbon 72-73 checkpoint kinase 1 Homo sapiens 282-286 16483564-0 2006 Vitamins C and E protect hepatic cytochrome P450 dysfunction induced by polymicrobial sepsis. Carbon 9-10 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 33-48 16526637-3 2006 The key intermediate in the reaction is the nitrooxyalkylperoxy radical, which is formed by the addition of NO3 to the carbon-carbon double bond and subsequent addition of O2. Carbon 119-125 NBL1, DAN family BMP antagonist Homo sapiens 108-111 16330546-0 2006 Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds. Carbon 164-170 triosephosphate isomerase 1 Homo sapiens 129-132 16330546-0 2006 Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds. Carbon 171-177 triosephosphate isomerase 1 Homo sapiens 129-132 16330546-6 2006 Surprisingly, the residues forming this cation-binding site and most of their interaction partners are shared with three other TIM barrel enzymes that catalyze diverse carbon-carbon bond cleavage reactions believed to proceed through enolate intermediates (4-hydroxy-2-ketovalerate aldolase, 2-isopropylmalate synthase, and transcarboxylase 5S). Carbon 168-174 triosephosphate isomerase 1 Homo sapiens 127-130 16330546-6 2006 Surprisingly, the residues forming this cation-binding site and most of their interaction partners are shared with three other TIM barrel enzymes that catalyze diverse carbon-carbon bond cleavage reactions believed to proceed through enolate intermediates (4-hydroxy-2-ketovalerate aldolase, 2-isopropylmalate synthase, and transcarboxylase 5S). Carbon 175-181 triosephosphate isomerase 1 Homo sapiens 127-130 16529466-0 2006 Acetylenic carbon-13 chemical shift tensors for diphenylacetylene and (eta2-Diphenylacetylene)Pt(PPh3)2: a solid-state NMR and theoretical study. Carbon 11-17 caveolin 1 Homo sapiens 97-101 16529466-2 2006 An investigation of the chemical shift (CS) tensors of the 13C-labeled carbons in Ph13C13CPh and (eta2-Ph13C13CPh)Pt(PPh3)2. Carbon 71-78 caveolin 1 Homo sapiens 117-121 16526788-2 2006 BF2 complexes with only one pyrrole NH interaction site (2d,e), which exhibit smaller affinities than the basic structure (2b), bind anions tightly, which is inferred by UV/vis absorption spectral changes, compared to the derivatives with an alkyl group at the bridging carbon (2f) or two pyrrole nitrogen sites (2c). Carbon 270-276 forkhead box G1 Homo sapiens 0-3 16526637-3 2006 The key intermediate in the reaction is the nitrooxyalkylperoxy radical, which is formed by the addition of NO3 to the carbon-carbon double bond and subsequent addition of O2. Carbon 126-132 NBL1, DAN family BMP antagonist Homo sapiens 108-111 16496991-1 2006 4-Phenyl-1,4-dihydropyridine-3,5-dicarboxylates contain two pi chromophores separated by an sp3 carbon. Carbon 96-102 Sp3 transcription factor Homo sapiens 92-95 16482354-14 2006 Thermal analysis shows that I2 cleavage occurs in that temperature region above 200 degrees C when C-S bonds are broken and CS2 and I2 are simultaneously liberated. Carbon 92-93 chorionic somatomammotropin hormone 2 Homo sapiens 124-127 16482354-15 2006 Performed at 270 degrees C thermolysis of alpha,beta-C4S6.I2 yields under cleavage of I2 and CS2 a black polymeric carbon sulfide (CS)x which is probably a mixture of graphitic carbon and unidentified amorphous polymeric carbon sulfides. Carbon 115-121 chorionic somatomammotropin hormone 2 Homo sapiens 93-96 16503617-4 2006 C-PTH peptide fragments were isolated from plasma samples by immunoaffinity extraction. Carbon 0-1 parathyroid hormone Homo sapiens 2-5 16415064-1 2006 To clarify the contributions of fructose-1,6-bisphosphatase (FBPase) and sedoheptulose-1,7-bisphosphatase (SBPase) separately to the carbon flux in the Calvin cycle, we generated transgenic tobacco plants expressing cyanobacterial FBPase-II in chloroplasts (TpF) or Chlamydomonas SBPase in chloroplasts (TpS). Carbon 133-139 alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1-like Nicotiana tabacum 304-307 16361229-3 2006 Moreover, we provide evidence that Glc7-Reg1 phosphatase acts as an upstream activator of Yck1,2 kinases in a novel signaling pathway that modulates kinase activity in response to carbon source availability. Carbon 180-186 protein phosphatase regulator REG1 Saccharomyces cerevisiae S288C 40-44 16337793-2 2006 For the development of imaging agents, we have synthesized novel derivatives of recently reported diphenylsulfide SERT ligands, in which the sulfur atom linking the two phenyl rings was replaced by an oxygen, sulfinyl, sulfonyl, amino or carbon group. Carbon 238-244 solute carrier family 6 member 4 Homo sapiens 114-118 17193060-1 2006 Highly dispersed and debundled carbon nanotubes were prepared in an aqueous solution of lysozyme using a combination of ultrasonication and ultracentrifugation. Carbon 31-37 lysozyme Homo sapiens 88-96 16448058-1 2006 A highly sensitive flow injection amperometric biosensor for organophosphate pesticides and nerve agents based on self-assembled acetylcholinesterase (AChE) on a carbon nanotube (CNT)-modified glassy carbon (GC) electrode is described. Carbon 162-168 acetylcholinesterase (Cartwright blood group) Homo sapiens 151-155 16372180-1 2006 A new electroactive label has been used to monitor immunoassays in the determination of human serum albumin (HSA) using glassy-carbon electrodes as supports for the immunological reactions. Carbon 127-133 albumin Homo sapiens 94-107 16448058-1 2006 A highly sensitive flow injection amperometric biosensor for organophosphate pesticides and nerve agents based on self-assembled acetylcholinesterase (AChE) on a carbon nanotube (CNT)-modified glassy carbon (GC) electrode is described. Carbon 200-206 acetylcholinesterase (Cartwright blood group) Homo sapiens 151-155 16471597-8 2006 In the latter case, some 13C resonances can be assigned to sp3 hybridized carbons and to the quinoid group. Carbon 74-81 Sp3 transcription factor Homo sapiens 59-62 16364349-2 2006 In the present study, detailed structures of oligosaccharides released from Thy-1 were elucidated by mass spectrometric oligosaccharide profiling using LC/MS with a graphitized carbon column (GCC-LC/MS). Carbon 177-183 Thy-1 cell surface antigen Rattus norvegicus 76-81 16461666-10 2006 Transposon mutants of quiP were defective for growth when P. aeruginosa was cultured in medium containing decanoyl-HSL as a sole carbon and energy source. Carbon 129-135 acyl-homoserine lactone acylase QuiP Pseudomonas aeruginosa PAO1 22-26 16489927-6 2006 Obviously, carbon and nitrogen metabolism in the rat liver can be controlled through redistribution of 2-oxoglutarate between different metabolic processes via regulatory mechanisms influencing differently located forms of NADP-IDH and AsAT. Carbon 11-17 glutamic-oxaloacetic transaminase 2 Rattus norvegicus 236-240 16485900-6 2006 Absolute configurations at the C(7,8) carbons of the FBP derivatives were determined by comparison of the circular dichroism (CD) spectra with those reported for the BP analogues. Carbon 38-45 ECB2 Homo sapiens 53-56 16240314-0 2006 Binding of acetylcholinesterase to multiwall carbon nanotube-cross-linked chitosan composite for flow-injection amperometric detection of an organophosphorous insecticide. Carbon 45-51 acetylcholinesterase (Cartwright blood group) Homo sapiens 11-31 16240314-1 2006 A novel method for immobilization of acetylcholinesterase (AChE) by binding covalently to a cross-linked chitosan-multiwall carbon nanotube (MWNT) composite is described. Carbon 124-130 acetylcholinesterase (Cartwright blood group) Homo sapiens 37-57 16240314-1 2006 A novel method for immobilization of acetylcholinesterase (AChE) by binding covalently to a cross-linked chitosan-multiwall carbon nanotube (MWNT) composite is described. Carbon 124-130 acetylcholinesterase (Cartwright blood group) Homo sapiens 59-63 16438587-0 2006 Comparing reactions of H and Cl with C-H stretch-excited CHD3. Carbon 0-1 chromodomain helicase DNA binding protein 3 Homo sapiens 57-61 16504293-9 2006 Moreover, polyinosinic polycytidylic acid (poly I:C) induced increased GBP transcript levels in RTS11 and RTG2 cells after 4-6 h of stimulation, and in head kidney and liver of live fish after 24 h. These studies suggest that rbtGBP is an early response gene in rainbow trout, which may have similar functions in IFN-gamma mediated responses as mammalian GBPs. Carbon 50-51 interferon, gamma Oncorhynchus mykiss 313-322 16407567-9 2006 The BNP effect was blocked by the ryanodine receptor modulators caffeine, ryanodine, and ruthenium red but not by the IP3 receptor antagonists heparin and xestospongin-C. Carbon 168-169 natriuretic peptide B Rattus norvegicus 4-7 16275640-4 2006 Polyunsaturated fatty acids of the C18 and C20 series containing at least three double bonds located from carbon 9 (or closer to the carboxyl group) were equally effective as AA in restoring 5-LO translocation in pyrrophenone-treated agonist-activated PMN. Carbon 106-112 Bardet-Biedl syndrome 9 Homo sapiens 35-38 15993046-0 2006 The interface behavior and biocatalytic activity of superoxide dismutase at carbon nanotube. Carbon 76-82 superoxide dismutase 1 Homo sapiens 52-72 15993046-1 2006 The interface behavior and biocatalytic activity of superoxide dismutase (SOD) were studied at carbon nanotube (CNT) surface with cyclic voltammetry (CV). Carbon 95-101 superoxide dismutase 1 Homo sapiens 52-72 15993046-1 2006 The interface behavior and biocatalytic activity of superoxide dismutase (SOD) were studied at carbon nanotube (CNT) surface with cyclic voltammetry (CV). Carbon 95-101 superoxide dismutase 1 Homo sapiens 74-77 16423036-3 2006 Stimulation of HCECs with the TLR3 agonist poly(I:C) induced the activation of nuclear factor (NF)-kappaB and production of the proinflammatory cytokine interleukin (IL)-6 and the chemokine IL-8. Carbon 50-52 nuclear factor kappa B subunit 1 Homo sapiens 79-105 16423036-3 2006 Stimulation of HCECs with the TLR3 agonist poly(I:C) induced the activation of nuclear factor (NF)-kappaB and production of the proinflammatory cytokine interleukin (IL)-6 and the chemokine IL-8. Carbon 50-52 interleukin 6 Homo sapiens 153-171 16423036-3 2006 Stimulation of HCECs with the TLR3 agonist poly(I:C) induced the activation of nuclear factor (NF)-kappaB and production of the proinflammatory cytokine interleukin (IL)-6 and the chemokine IL-8. Carbon 50-52 C-X-C motif chemokine ligand 8 Homo sapiens 190-194 17114104-0 2006 Determination of Pb(II) with a dithizone-modified carbon paste electrode. Carbon 50-56 submaxillary gland androgen regulated protein 3B Homo sapiens 17-23 16484076-7 2006 The degradation rate of n-alkanes with carbon numbers ranging from C10 to C15 was relatively greater than that of n-alknaes with carbon numbers ranging from C16 to C20. Carbon 39-45 homeobox C10 Homo sapiens 67-70 17114104-1 2006 A dithizone (DTZ) modified carbon paste electrode was developed for the sensitive and selective determination of Pb(II) using differential pulse anodic stripping voltammetry as well in batch as in FIA system. Carbon 27-33 submaxillary gland androgen regulated protein 3B Homo sapiens 113-119 17294959-5 2006 The results indicate that the oxidation treatment changed the pore structure of the AC and modified the carbon surface by creating chemical components such as MnO4-, Mn4+, O, NO3-, Fe3+, Cl-, etc. Carbon 104-110 NBL1, DAN family BMP antagonist Homo sapiens 175-178 16331107-6 2006 In the AII-infused rats treated with olmesartan medoxomil, an AT1R blocker, we were interested to observe significant decreases in plasma TC and non-high-density lipoprotein (HDL)-cholesterol (C) (TC minus HDL-C), and liver cholesterol content were also decreased. Carbon 209-211 angiotensinogen Rattus norvegicus 7-10 16207701-11 2006 Several proteins with diverse functions outside primary carbon metabolism, such as the isomerase ROC4, lipoxygenase 2 involved in jasmonic acid biosynthesis, and a carbonic anhydrase (CA1), were surprisingly abundant in the range of 0.75-1.5% of the total stromal mass. Carbon 56-62 rotamase CYP 4 Arabidopsis thaliana 97-101 16308562-3 2005 In Saccharomyces cerevisiae, the conserved protein kinase A (PKA) and rapamycin-sensitive TOR (TORC1) pathways antagonize G0 entry in response to carbon and/or nitrogen availability primarily by inhibiting the PAS kinase Rim15 function. Carbon 146-152 protein kinase RIM15 Saccharomyces cerevisiae S288C 221-226 16326926-4 2006 T-DNA insertions in three corresponding genes, ptac2, -6, and -12, are lethal without exogenous carbon sources. Carbon 96-102 plastid transcriptionally active 2 Arabidopsis thaliana 47-52 16367965-1 2006 Ammonia assimilation by the plastidic glutamine synthetase/glutamate synthase system requires 2-oxoglutarate (2-OG) as a carbon precursor. Carbon 121-127 glutamine synthetase Nicotiana tabacum 38-58 16749434-10 2006 Overall results showed that with high carbon fraction induced to the cultivation, the PO4 and NO3 can remove up to 20% in single cultivation. Carbon 38-44 NBL1, DAN family BMP antagonist Homo sapiens 94-97 16277614-3 2005 With respect to the effects of the stereochemistry of the phenylisopropylamines, those with the (R) absolute configuration at the alpha carbon had higher intrinsic activities for hydrolysis of phosphatidyl inositol in a cell line expressing the human 5-HT 2A receptor compared to those with the (S) absolute configuration. Carbon 136-142 5-hydroxytryptamine receptor 2A Homo sapiens 251-267 16475328-3 2005 We used bacterial biovolume and a conversion factor to calculate bacterial carbon, which was used to normalize PCB concentrations. Carbon 75-81 pyruvate carboxylase Homo sapiens 111-114 16475328-4 2005 The range of total PCB concentrations in the bacterial fraction (61-337 ng/g organic carbon; OC) was similar, but generally higher than that of the total particulate fraction (36-324 ng/g OC). Carbon 85-91 pyruvate carboxylase Homo sapiens 19-22 16257661-4 2005 The O(2)(-) sensor uses covalent immobilization of cytochrome c via a binder, DTSSP (3,3"-dithio-bis(sulphosuccinimidylpropionate) onto the surface of the Au electrodes, whereas the NO sensor system involves an NiTSPc (nickel tetrasulfonated phthalocyanine) film electrodeposited onto the surface of the carbon electrodes and subsequently covered with an external layer of Nafion. Carbon 304-310 cytochrome c, somatic Homo sapiens 51-63 16331899-6 2005 In the case of propyne, C 1s excitations from each of the three chemically inequivalent carbon atoms are observed. Carbon 88-94 complement C1s Homo sapiens 24-28 16331964-1 2005 Human short-chain acyl-CoA dehydrogenase (hSCAD) catalyzes the first matrix step in the mitochondrial beta-oxidation cycle for substrates with four and six carbons. Carbon 156-163 acyl-CoA dehydrogenase short chain Homo sapiens 42-47 16261247-1 2005 A 1 : 1 Lewis acid-base complex between CyN=C=NCy and PhBCl2 has been isolated and structurally characterized, heating of which in refluxing toluene results in the amidinate, [PhC{NCy}2]BCl2; the overall reaction has been modeled by DFT calculations. Carbon 40-41 BCL2 apoptosis regulator Homo sapiens 56-60 16283723-7 2005 Furthermore, the voltammetric behavior of Au-cyt c at DNA modified glassy carbon electrode has been investigated for extending the application of Au-cyt c. Carbon 74-80 cytochrome c, somatic Homo sapiens 45-50 16231883-2 2005 The isotope effect on V/K is inverse, D3V/K = 0.93 +/- 0.03, which is consistent with conversion of the sp2 hybridized carbonyl carbon of the scissile ester bond of the E + A reactant state to a quasi-tetrahedral structure in the acylation transition state. Carbon 119-125 Sp2 transcription factor Homo sapiens 104-107 16171804-3 2005 We isolated the pan1-11 yeast mutant unable to grow on oleate as a sole carbon source and, therefore, exhibiting the Oleate- phenotype. Carbon 72-78 Pan1p Saccharomyces cerevisiae S288C 16-20 16171804-11 2005 Our results indicate that Pan1p, and possibly other components of the actin cytoskeleton, are necessary to properly regulate growth of dividing cells in response to the presence of some alternative carbon sources in the medium. Carbon 198-204 Pan1p Saccharomyces cerevisiae S288C 26-31 16244140-6 2005 Further analysis revealed that starch accumulation in NtSPSC-silenced plants was not due to an increased partitioning of carbon into starch, but rather showed that starch mobilization was impaired. Carbon 121-127 probable sucrose-phosphate synthase 4 Nicotiana tabacum 54-60 16447436-2 2005 Activated carbon was oxidized in HNO3 aqueous solution at first (AC1), then treated in the mixture of NaOH and NaCl solution (AC2). Carbon 10-16 adenylate cyclase 2 Homo sapiens 126-129 16447436-9 2005 Subsequent 2nd modification replaced H+ of carbon surface groups by Na+, the acidity of AC2 was decreased. Carbon 43-49 adenylate cyclase 2 Homo sapiens 88-91 16260593-2 2005 We demonstrate that the ARE-bearing MFA2 3" untranslated region (UTR) controls translation efficiency in a p38 MAPK/Hog1p-dependent manner in response to carbon source growth conditions. Carbon 154-160 mitogen-activated protein kinase HOG1 Saccharomyces cerevisiae S288C 116-121 16260593-4 2005 Pub1p binds the MFA2 3"-UTR in a p38 MAPK/Hog1p-regulated manner in response to carbon source growth conditions. Carbon 80-86 mitogen-activated protein kinase HOG1 Saccharomyces cerevisiae S288C 42-47 16260593-5 2005 Significantly, the p38 MAPK/Hog1p is also required to modulate Pab1p in response to carbon source. Carbon 84-90 mitogen-activated protein kinase HOG1 Saccharomyces cerevisiae S288C 28-33 16260593-8 2005 Importantly, Pab1p binds the MFA2 3"-UTR only in a PUB1 strain, and correlating with this requirement, Pub1p controls translation repression of MFA2 in a carbon source/Hog1p-regulated manner. Carbon 154-160 mitogen-activated protein kinase HOG1 Saccharomyces cerevisiae S288C 168-173 16245689-4 2005 AChE is shown to hydrolyze only those substrates that form equilibrium conformers compatible in the mutual arrangement of trimethylammonium group, carbonyl carbon, and carbonyl oxygen with the tt conformation of ACh; in this case, the rate of substrate hydrolysis depends on the total population of these conformers. Carbon 147-153 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 16030250-2 2005 The Saccharomyces cerevisiae GPCR Gpr1 and associated Galpha subunit Gpa2 sense extracellular carbon sources (including glucose) to govern filamentous growth. Carbon 94-100 guanine nucleotide-binding protein subunit alpha Saccharomyces cerevisiae S288C 69-73 16039977-0 2005 Direct electrochemistry and electrocatalytic activity of catalase incorporated onto multiwall carbon nanotubes-modified glassy carbon electrode. Carbon 94-100 catalase Homo sapiens 57-65 16039977-0 2005 Direct electrochemistry and electrocatalytic activity of catalase incorporated onto multiwall carbon nanotubes-modified glassy carbon electrode. Carbon 127-133 catalase Homo sapiens 57-65 16039977-1 2005 The direct voltammetry and electrocatalytic properties of catalase, which was adsorbed on the surface of multiwall carbon nanotubes (MWCNTs), was investigated. Carbon 115-121 catalase Homo sapiens 58-66 16039977-3 2005 The surface coverage of catalase immobilized on MWCNTs glassy carbon electrode was approximately 2.4x10(-10) molcm-2. Carbon 62-68 catalase Homo sapiens 24-32 16019141-1 2005 In the present study, a deeper understanding of adsorption behavior of Pb(II) from aqueous systems onto activated carbon and treated activated carbon has been attempted via static and column mode studies under various conditions. Carbon 114-120 submaxillary gland androgen regulated protein 3B Homo sapiens 71-77 16019141-1 2005 In the present study, a deeper understanding of adsorption behavior of Pb(II) from aqueous systems onto activated carbon and treated activated carbon has been attempted via static and column mode studies under various conditions. Carbon 143-149 submaxillary gland androgen regulated protein 3B Homo sapiens 71-77 16019141-7 2005 The extent of Pb(II) removal was found to be higher in the treated activated carbon. Carbon 77-83 submaxillary gland androgen regulated protein 3B Homo sapiens 14-20 16202879-1 2005 In this study, a 15-lipoxygenase-modified carbon paste electrode (15-LOX-MCPE) was developed in connection with the help of voltammetry, which can be used as an assay system for screening drugs with inhibiting lipoxygenase (LOX) activity. Carbon 42-48 arachidonate 15-lipoxygenase Homo sapiens 17-32 16209582-0 2005 Stereoselective formation of carbon-carbon bonds via SN2-displacement: synthesis of substituted cycloalkyl[b]indoles. Carbon 29-35 solute carrier family 38 member 5 Homo sapiens 53-56 16209582-0 2005 Stereoselective formation of carbon-carbon bonds via SN2-displacement: synthesis of substituted cycloalkyl[b]indoles. Carbon 36-42 solute carrier family 38 member 5 Homo sapiens 53-56 16027155-3 2005 Here, we demonstrate that cis-acyclic retinals, lacking four carbon atoms of the ring, can activate rhodopsin. Carbon 61-67 rhodopsin Homo sapiens 100-109 16190768-1 2005 We have designed and synthesized the first two high affinity covalent anandamide probes for the CB1 receptor by introducing either an electrophilic isothiocyanato or a photoactivatable azido group at the terminal carbon of the arachidonic acid moiety. Carbon 213-219 cannabinoid receptor 1 Homo sapiens 96-99 16194105-0 2005 Insulin oxidation and determination at carbon electrodes. Carbon 39-45 insulin Homo sapiens 0-7 16194105-1 2005 The redox chemistry of insulin was investigated at glassy carbon (GC) electrodes that were coated with films of chitosan (CHIT) and multiwalled carbon nanotubes (CNT). Carbon 58-64 insulin Homo sapiens 23-30 16194105-1 2005 The redox chemistry of insulin was investigated at glassy carbon (GC) electrodes that were coated with films of chitosan (CHIT) and multiwalled carbon nanotubes (CNT). Carbon 144-150 insulin Homo sapiens 23-30 16218699-0 2005 Carbon nanotube inner phase chemistry: the Cl- exchange SN2 reaction. Carbon 0-6 solute carrier family 38 member 5 Homo sapiens 56-59 16853240-8 2005 The carbon K edge in electron energy loss spectroscopy (EELS) of a sample after 24 h under stream shows that these carbonaceous deposits consist of a mixture of sp2- and sp3-hybridized carbons. Carbon 4-10 Sp2 transcription factor Homo sapiens 161-164 16853240-8 2005 The carbon K edge in electron energy loss spectroscopy (EELS) of a sample after 24 h under stream shows that these carbonaceous deposits consist of a mixture of sp2- and sp3-hybridized carbons. Carbon 4-10 Sp3 transcription factor Homo sapiens 170-173 16853240-8 2005 The carbon K edge in electron energy loss spectroscopy (EELS) of a sample after 24 h under stream shows that these carbonaceous deposits consist of a mixture of sp2- and sp3-hybridized carbons. Carbon 185-192 Sp3 transcription factor Homo sapiens 170-173 16114890-1 2005 A strategy to detect P-glycoprotein (P-gp) on cell membrane and quantify the cell number using electrochemical immunoassay was developed by effective surface immunoreactions and immobilization of cells on a highly hydrophilic interface, which was constructed by adsorption of colloidal gold nanoparticles on a methoxysilyl-terminated (Mos) butyrylchitosan modified glassy carbon electrode (Au-CS/GCE). Carbon 372-378 ATP binding cassette subfamily B member 1 Homo sapiens 21-35 15970472-0 2005 A reagentless biosensor of nitric oxide based on direct electron transfer process of cytochrome c on multi-walled carbon nanotube. Carbon 114-120 cytochrome c, somatic Homo sapiens 85-97 15970472-1 2005 Direct electron transfer between Cytochrome c (Cyt.c) and electrode can be achieved through immobilizing Cyt.c on the surface of multi-walled carbon nanotubes (MWNTs). Carbon 142-148 cytochrome c, somatic Homo sapiens 33-45 15970472-1 2005 Direct electron transfer between Cytochrome c (Cyt.c) and electrode can be achieved through immobilizing Cyt.c on the surface of multi-walled carbon nanotubes (MWNTs). Carbon 142-148 cytochrome c, somatic Homo sapiens 47-52 15970472-1 2005 Direct electron transfer between Cytochrome c (Cyt.c) and electrode can be achieved through immobilizing Cyt.c on the surface of multi-walled carbon nanotubes (MWNTs). Carbon 142-148 cytochrome c, somatic Homo sapiens 105-110 15970472-2 2005 Under the condition of cyclic potential scans, Cyt.c can be adsorbed on the surface of MWNTs that were modified on a glassy carbon (GC) electrode to form an approximate monolayer. Carbon 124-130 cytochrome c, somatic Homo sapiens 47-52 16157534-1 2005 UNLABELLED: (11)C-N,N-Dimethyl-2-(2-amino-4-methylphenylthio)benzylamine ((11)C-MADAM) is a newly synthesized radioligand with high selectivity and specificity for the serotonin transporter (5-HTT) in a monkey model. Carbon 16-17 solute carrier family 6 member 4 Homo sapiens 168-189 16157534-1 2005 UNLABELLED: (11)C-N,N-Dimethyl-2-(2-amino-4-methylphenylthio)benzylamine ((11)C-MADAM) is a newly synthesized radioligand with high selectivity and specificity for the serotonin transporter (5-HTT) in a monkey model. Carbon 16-17 solute carrier family 6 member 4 Homo sapiens 191-196 16101709-1 2005 Short-chain acyl-CoA dehydrogenase (SCAD) is a mitochondrial enzyme that catalyzes the dehydrogenation of short chain fatty acids (4 to 6 carbons in length) thereby initiating the cycle of beta-oxidation. Carbon 138-145 acyl-CoA dehydrogenase short chain Homo sapiens 0-34 16101709-1 2005 Short-chain acyl-CoA dehydrogenase (SCAD) is a mitochondrial enzyme that catalyzes the dehydrogenation of short chain fatty acids (4 to 6 carbons in length) thereby initiating the cycle of beta-oxidation. Carbon 138-145 acyl-CoA dehydrogenase short chain Homo sapiens 36-40 16117499-1 2005 We present the first electrochemical detection, characterization, and kinetic study of the aggregation of Alzheimer"s disease (AD) amyloid beta peptides (Abeta-40, Abeta-42) using three different voltammetric techniques at a glassy carbon electrode (GCE). Carbon 232-238 amyloid beta precursor protein Homo sapiens 131-143 16114890-1 2005 A strategy to detect P-glycoprotein (P-gp) on cell membrane and quantify the cell number using electrochemical immunoassay was developed by effective surface immunoreactions and immobilization of cells on a highly hydrophilic interface, which was constructed by adsorption of colloidal gold nanoparticles on a methoxysilyl-terminated (Mos) butyrylchitosan modified glassy carbon electrode (Au-CS/GCE). Carbon 372-378 ATP binding cassette subfamily B member 1 Homo sapiens 37-41 16197231-2 2005 Our results show that a sp2 bonded cap is formed on an iron catalyst, following the diffusion of C atoms from hydrocarbon precursors on the nanoparticle surface. Carbon 97-98 Sp2 transcription factor Homo sapiens 24-27 16197266-0 2005 Comment on "Band filling and interband scattering effects in MgB2: carbon versus aluminium doping". Carbon 67-73 secretoglobin family 2A member 1 Homo sapiens 61-65 16075109-1 2005 Multi-stage mass spectrometry (MSn) on [(M + Ag - H)x + Ag]+ precursor ions (where M = an amino acid such as glycine or N,N-dimethylglycine) results in the formation of stable silver (Ag3+, Ag5+ and Ag7+) and silver hydride (Ag2H+, Ag4H+ and Ag6H+) cluster cations in the gas phase. Carbon 190-193 moesin Homo sapiens 31-34 15964843-7 2005 Our results are congruent with a hypothesis that anandamide approaches its binding site by laterally diffusing within one membrane leaflet in an extended conformation and interacts with a hydrophobic groove formed by helices 3 and 6 of CB1, where its terminal carbon is positioned close to a key cysteine residue in helix 6 leading to receptor activation. Carbon 260-266 cannabinoid receptor 1 Homo sapiens 236-239 15893873-0 2005 Interactions of cytochrome c with DNA at glassy carbon surface. Carbon 48-54 cytochrome c, somatic Homo sapiens 16-28 16082663-4 2005 The conformational changes of cyt c induced by its adsorption at a bare glassy carbon electrode/solution interface and the effect of the electric field on the ligation state of the heme can be avoided at the colloidal-Au-modified electrode/solution interface. Carbon 79-85 cytochrome c, somatic Homo sapiens 30-35 15893873-1 2005 Cyclic voltammetry (CV) was used to investigate the interactions of Cytochrome c (Cyt c) with deoxyribonucleic acid (DNA) at glassy carbon (GC) electrodes. Carbon 132-138 cytochrome c, somatic Homo sapiens 68-80 15893873-1 2005 Cyclic voltammetry (CV) was used to investigate the interactions of Cytochrome c (Cyt c) with deoxyribonucleic acid (DNA) at glassy carbon (GC) electrodes. Carbon 132-138 cytochrome c, somatic Homo sapiens 82-87 16262058-1 2005 Correlation and cluster analyses on the enzyme activities and chemical-biological properties of eight red soils showed that soil urease, invertase, phosphatase and catalase activities correlated significantly with soil organic carbon, total nitrogen and total phosphorous. Carbon 227-233 catalase Homo sapiens 164-172 16109560-1 2005 OBJECTIVE: To observe the expression of Bcl-2 and Bax proteins and cell apoptosis induced by preoperative lymphatic chemotherapy with epirubicin-activated carbon suspension (Epi-CH) in the cells of axillary metastatic lymph node of breast cancer and investigate the mechanism. Carbon 155-161 BCL2 apoptosis regulator Homo sapiens 40-45 16109560-1 2005 OBJECTIVE: To observe the expression of Bcl-2 and Bax proteins and cell apoptosis induced by preoperative lymphatic chemotherapy with epirubicin-activated carbon suspension (Epi-CH) in the cells of axillary metastatic lymph node of breast cancer and investigate the mechanism. Carbon 155-161 BCL2 associated X, apoptosis regulator Homo sapiens 50-53 16000118-6 2005 (1)H NMR study showed that 1SS(C(3)-C(9)) has two conformations, which contain a cis- (70%) or trans- (30%) Pro residue, while MST-2SS as well as MST(1-12) takes a single conformation containing only a cis-Pro residue. Carbon 31-32 serine/threonine kinase 3 Homo sapiens 127-132 15935916-9 2005 The results demonstrate the existence of sp2-bonded carbon in the vicinity of stacking faults and partial dislocations in CVD diamond as well as additional states below conduction band, tailing deep into the band gap, at a node in a perfect dislocation. Carbon 52-58 Sp2 transcription factor Homo sapiens 41-44 16158266-0 2005 Improved electrochemical analysis of neuropathy target esterase activity by a tyrosinase carbon paste electrode modified by 1-methoxyphenazine methosulfate. Carbon 89-95 patatin like phospholipase domain containing 6 Homo sapiens 37-63 16021449-4 2005 A several-fold increase in mRF1 levels slightly inhibits the growth of wild-type cells on media containing a non-fermentable carbon source. Carbon 125-131 retroperitoneal fat pad weight 1 Mus musculus 27-31 16132698-5 2005 In the present study the effect of carbon ion irradiation on p 44/42 MAPK and NF-kappaB, which are essentially survival factors, have been studied. Carbon 35-41 nuclear factor kappa B subunit 1 Homo sapiens 78-87 15996103-7 2005 Using (13)C-filtered, (13)C-edited NMR experiments, dramatic changes in intermolecular contacts between residues in the C-terminal domain of CaM-L7 and C28W accompany oxidation of M144 and M145, with an essentially complete loss of contacts between C28W and M144 and M145. Carbon 10-11 calmodulin 1 Homo sapiens 141-144 15996103-7 2005 Using (13)C-filtered, (13)C-edited NMR experiments, dramatic changes in intermolecular contacts between residues in the C-terminal domain of CaM-L7 and C28W accompany oxidation of M144 and M145, with an essentially complete loss of contacts between C28W and M144 and M145. Carbon 26-27 calmodulin 1 Homo sapiens 141-144 15718292-3 2005 Of the endogenous ligands known to activate PXR, biliary bile salts vary the most across vertebrate species, ranging from 27-carbon (C27) bile alcohol sulfates (early fish, amphibians) to C24 bile acids (birds, mammals). Carbon 125-131 nuclear receptor subfamily 1, group I, member 2 Danio rerio 44-47 15896708-3 2005 We show that Anc1 is required for growth on galactose as the sole carbon source, and that it is recruited to the UAS of the GAL1 gene after induction. Carbon 66-72 TATA-binding protein-associated factor TAF14 Saccharomyces cerevisiae S288C 13-17 15994921-5 2005 The distinctive differences in metabolic profiles of K12 and K13 codon mutated cells indicate that a strong correlation exists between the flow of glucose carbons towards either increased anaerobic glycolysis, and resistance to apoptosis (K12), or increased macromolecule synthesis, rapid proliferation, and increased sensitivity to apoptosis. Carbon 155-162 keratin 12 Mus musculus 53-56 15994921-5 2005 The distinctive differences in metabolic profiles of K12 and K13 codon mutated cells indicate that a strong correlation exists between the flow of glucose carbons towards either increased anaerobic glycolysis, and resistance to apoptosis (K12), or increased macromolecule synthesis, rapid proliferation, and increased sensitivity to apoptosis. Carbon 155-162 keratin 12 Mus musculus 239-242 16045294-6 2005 Examples are given for both finite/closed cages and infinite/open all-sp2 carbon structures. Carbon 74-80 Sp2 transcription factor Homo sapiens 70-73 15967713-4 2005 Recently, PIS1 expression was found to be regulated in response to carbon source and oxygen availability. Carbon 67-73 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 10-14 16053113-2 2005 The derived carbons are designated as FAC (activated carbon derived from coconut shell fibers without any treatment) and ATFAC (activated carbon derived from acid treated coconut shell fibers). Carbon 12-19 FA complementation group C Homo sapiens 38-41 16053113-2 2005 The derived carbons are designated as FAC (activated carbon derived from coconut shell fibers without any treatment) and ATFAC (activated carbon derived from acid treated coconut shell fibers). Carbon 12-18 FA complementation group C Homo sapiens 38-41 16053113-5 2005 The monolayer adsorption capacity (Q0) as calculated using Langmuir adsorption isotherm of the activated carbons viz., FAC and ATFAC is found to increase with an increase in temperature confirming the endothermic process. Carbon 105-112 FA complementation group C Homo sapiens 119-122 15998807-4 2005 The AIP2 E3 ligase activity is abolished by mutations (C230S; C231S) in the RING motif and the AIP2 (C/S) mutant functions in a dominant-negative manner. Carbon 55-56 WW domain containing E3 ubiquitin protein ligase 2 Homo sapiens 4-8 16240586-1 2005 Nanoparticles of organic carbon (NOC) are formed in combustion of hydrocarbon-rich fuels and have been detected in vehicle exhausts, suggesting their presence in urban atmospheres. Carbon 25-31 nocturnin Homo sapiens 33-36 15890364-10 2005 We suggest that Gis4 may explain the glucose repression defects in carbon source metabolism for the grr1 mutants. Carbon 67-73 Gis4p Saccharomyces cerevisiae S288C 16-20 15948967-7 2005 GDH3 carbon-mediated regulation is over-imposed to that exerted by the nitrogen source, highlighting the fact that operation of facultative metabolism requires strict control of enzymes, like Gdh3p, involved in biosynthetic pathways that use tricarboxylic acid cycle intermediates. Carbon 5-11 glutamate dehydrogenase (NADP(+)) GDH3 Saccharomyces cerevisiae S288C 0-4 15948967-7 2005 GDH3 carbon-mediated regulation is over-imposed to that exerted by the nitrogen source, highlighting the fact that operation of facultative metabolism requires strict control of enzymes, like Gdh3p, involved in biosynthetic pathways that use tricarboxylic acid cycle intermediates. Carbon 5-11 glutamate dehydrogenase (NADP(+)) GDH3 Saccharomyces cerevisiae S288C 192-197 15969559-1 2005 Synthesis and characterization of Cp*Ru[eta3-HC(PPh2NPh)2], 1, reveals it to have a "piano stool" structure with the ligand bound to Ru(II) via two N and the unique, sp3 hybridized carbon. Carbon 181-187 Sp3 transcription factor Homo sapiens 166-169 16839080-6 2005 In the meso-substituted porhyrins (calixphyrins) the sp3 carbon atoms perturb their pi-electron system and significantly modify the molecular shape and the flexibility. Carbon 57-63 Sp3 transcription factor Homo sapiens 53-56 16852485-5 2005 This showed that the changes of free energy, enthalpy, and entropy of surface diffusion are linearly correlated with the carbon number in the alkyl ligands of the bonded phases and that the contribution of the C18 ligand to the changes of the thermodynamic parameters corresponds to that of the C10 ligand. Carbon 121-127 Bardet-Biedl syndrome 9 Homo sapiens 210-213 16852485-5 2005 This showed that the changes of free energy, enthalpy, and entropy of surface diffusion are linearly correlated with the carbon number in the alkyl ligands of the bonded phases and that the contribution of the C18 ligand to the changes of the thermodynamic parameters corresponds to that of the C10 ligand. Carbon 121-127 homeobox C10 Homo sapiens 295-298 16880981-0 2005 Influence of length on cytotoxicity of multi-walled carbon nanotubes against human acute monocytic leukemia cell line THP-1 in vitro and subcutaneous tissue of rats in vivo. Carbon 52-58 GLI family zinc finger 2 Homo sapiens 118-123 15890364-10 2005 We suggest that Gis4 may explain the glucose repression defects in carbon source metabolism for the grr1 mutants. Carbon 67-73 SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C 100-104 15914897-1 2005 The title compound, C(18)H(17)NO(4), crystallizes from ethanol at ambient temperature as two concomitant polymorphs (I) and (II), both monoclinic P2(1)/c with Z" = 1. Carbon 20-21 cyclin dependent kinase inhibitor 1A Homo sapiens 146-151 15926793-1 2005 Treatment of the phenyl-substituted silane 4 with lithium metal afforded the functionalized lithiosilane rac-2 by selective cleavage of one Si-C bond between silicon and a phenyl group. Carbon 143-144 Rac family small GTPase 2 Homo sapiens 105-110 16833862-4 2005 The ionization energies for the sp2 carbons are found to correlate well with activation energies for electrophilic addition and with proton affinities. Carbon 36-43 Sp2 transcription factor Homo sapiens 32-35 15941260-1 2005 We demonstrate a simple purification method of carbon nanotubes via sulfidation reaction of carbon, C + 2S --> CS2, to selectively remove carbonaceous impurities from nanotubes. Carbon 47-53 chorionic somatomammotropin hormone 2 Homo sapiens 114-117 15941260-1 2005 We demonstrate a simple purification method of carbon nanotubes via sulfidation reaction of carbon, C + 2S --> CS2, to selectively remove carbonaceous impurities from nanotubes. Carbon 92-98 chorionic somatomammotropin hormone 2 Homo sapiens 114-117 15941276-5 2005 These changes in chemical shift are unexpected given the results of previous Raman studies which revealed that the C3=C2-C1=O HD enone fragment is polarized upon binding to MCAD such that the electron density at the C3 and C1 carbons is reduced, not increased (Pellet et al. Carbon 226-233 acyl-CoA dehydrogenase medium chain Sus scrofa 173-177 15941276-9 2005 The large increase in shielding experienced by the C1 and C3 HD carbons in the HD-CoA/MCAD complex is proposed to arise from the ring current field from the isoalloxazine portion of the flavin cofactor. Carbon 64-71 acyl-CoA dehydrogenase medium chain Sus scrofa 86-90 15943835-2 2005 Some of these patients display a large amount of C-PTH fragments in circulation and present with a higher C-PTH/I-PTH ratio than seen in less severe cases of primary hyperparathyroidism. Carbon 49-50 parathyroid hormone Homo sapiens 51-54 16851717-1 2005 The adsorption of lysozyme (Lz) onto nanoporous carbon molecular sieves with various pore diameters has been studied at different solution pH values. Carbon 48-54 lysozyme Homo sapiens 18-26 15882277-10 2005 There was a weak correlation between the 1-84 PTH:C-PTH ratio and the DeltaHtSDS (r= 0.2, P= 0.01). Carbon 50-51 parathyroid hormone Homo sapiens 52-55 15809723-8 2005 Polyriboinosinic polyribocytidylic acid [poly (I:C)], double strand RNA, further enhanced CD86 expression and the therapeutic efficacy of vaccination with DCs pulsed with apoptotic cells for pre-established hepatoma. Carbon 49-51 CD86 antigen Mus musculus 90-94 15984801-0 2005 Congener-specific carbon isotopic analysis of technical PCB and PCN mixtures using two-dimensional gas chromatography-isotope ratio mass spectrometry. Carbon 18-24 pyruvate carboxylase Homo sapiens 56-59 15824074-0 2005 The role of alternative oxidase in modulating carbon use efficiency and growth during macronutrient stress in tobacco cells. Carbon 46-52 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 12-31 15863446-4 2005 Starch is the major carbon store in plants, and ADP-glucose pyrophosphorylase (AGPase) is the key regulatory enzyme of starch synthesis in the plastid. Carbon 20-26 glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic/amyloplastic Solanum tuberosum 48-77 15863446-4 2005 Starch is the major carbon store in plants, and ADP-glucose pyrophosphorylase (AGPase) is the key regulatory enzyme of starch synthesis in the plastid. Carbon 20-26 glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic/amyloplastic Solanum tuberosum 79-85 15863446-7 2005 Post-translational redox activation of AGPase in response to sugars is part of a signalling mechanism linking the rate of starch synthesis to the availability of carbon in diverse plant tissues. Carbon 162-168 glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic/amyloplastic Solanum tuberosum 39-45 15909499-3 2005 The DiamondBond C18 is a hybrid carbon clad zirconia (CCZ)-C18 stationary phase. Carbon 32-38 Bardet-Biedl syndrome 9 Homo sapiens 16-19 15909499-6 2005 However, this is at the expense of a portion of the two-dimensional peak capacity displayed by the C18-carbon clad zirconia system. Carbon 103-109 Bardet-Biedl syndrome 9 Homo sapiens 99-102 15974271-3 2005 The rates of color, dye and dissolved organic carbon removal were in the order of reactive blue 19 > Fast Green FCF > Eriochrome Black T. The generation of SO(2-)4, and N(O-)3, increased with the progress of the Fenton reaction. Carbon 46-52 NBL1, DAN family BMP antagonist Homo sapiens 175-181 15922398-3 2005 An activated carbon dose of 2% of the dry sediment mass lowered total aqueous PCB concentrations by more than 95% after 1 month of treatment and more than 98% after 6 months. Carbon 13-19 pyruvate carboxylase Homo sapiens 78-81 15922398-4 2005 Aqueous PCB concentrations remained below detection limits following 18 months of sediment-carbon contact in slowly mixed systems. Carbon 91-97 pyruvate carboxylase Homo sapiens 8-11 15922398-6 2005 These tests show that PCB sequestration with activated carbon improves with contact time and is not diminished by prolonged mixing with sediment. Carbon 55-61 pyruvate carboxylase Homo sapiens 22-25 15922398-7 2005 Desorption studies confirmed the sequestration, in which 74% of the total PCB mass could be desorbed from untreated Lake Hartwell sediment within 30 days as compared to only 7% after activated carbon treatment for 6 months. Carbon 193-199 pyruvate carboxylase Homo sapiens 74-77 15922398-8 2005 We compare these observations with marine sediment from San Francisco Bay and propose a conceptual model to rationalize how sediment properties relate to the reduction in aqueous PCB concentrations during activated carbon treatment. Carbon 215-221 pyruvate carboxylase Homo sapiens 179-182 15846428-1 2005 Probe beam deflection (PBD) and AC impedance are used to quantitatively evaluate the double layer properties of carbon aerogel electrodes in aqueous media (NaF). Carbon 112-118 C-X-C motif chemokine ligand 8 Homo sapiens 156-159 15866279-4 2005 For instance, the concentration of one of the most abundant congeners, PCB 52, was typically on the order of 0.1-0.3 pg l(-1) in the dissolved (melted) phase of the ice, snow, IIW, and underlying seawater while its particulate organic-carbon (POC) normalized concentrations were around 1-3 ng gPOC(-1) in the ice, snow, IIW, and IRS. Carbon 235-241 pyruvate carboxylase Homo sapiens 71-74 15811691-0 2005 Prediction of simultaneous adsorption of Cu(II) and Pb(II) onto activated carbon by conventional Langmuir type equations. Carbon 74-80 submaxillary gland androgen regulated protein 3B Homo sapiens 41-58 15811691-1 2005 Removal of Cu(II) and Pb(II) by adsorption onto activated carbon was examined in single- and binary-component aqueous solutions representative of contaminated solutions containing heavy metals. Carbon 58-64 submaxillary gland androgen regulated protein 3B Homo sapiens 11-28 15811691-4 2005 The adsorption sites per gram of activated carbon resulted in similar values for Cu(II) and Pb(II) from the isotherms. Carbon 43-49 submaxillary gland androgen regulated protein 3B Homo sapiens 81-98 16851717-1 2005 The adsorption of lysozyme (Lz) onto nanoporous carbon molecular sieves with various pore diameters has been studied at different solution pH values. Carbon 48-54 lysozyme Homo sapiens 28-30 16851717-5 2005 Moreover, the amount adsorbed depends on the pore size and pore volume of the nanoporous carbon adsorbents, indicating that the Lz molecules are adsorbed inside the mesopores. Carbon 89-95 lysozyme Homo sapiens 128-130 16851717-9 2005 In addition, FT-IR spectroscopic studies confirm that the Lz used in this study is stable even after the adsorption on the nanoporous carbon. Carbon 134-140 lysozyme Homo sapiens 58-60 15755667-8 2005 The docking studies between SH and BSA showed that the position of the oxygen atom of the hydroxyl group of SH (O(12)) was in favor of a nucleophilic attack on carbon atom of the amide bond of a beta-sheet (C(34)) because the distance between O(12) and C(34) was 3.37A. Carbon 160-166 albumin Homo sapiens 35-38 15839558-5 2005 A high mean value (3.15) of NO3-/elemental carbon (EC) ratio of HPD divided by that of LPD indicates that concentration variations due to chemical formation and nonchemical factors apparently were higher than those of the concentration variations due to nonchemical factors alone. Carbon 43-49 NBL1, DAN family BMP antagonist Homo sapiens 28-31 15771442-7 2005 The preferred alpha-ketoheterocycle is a pi-rich 2-substituted azole with at least two heteroatoms proximal to the carbon bearing the keto group, and a preferred thrombin inhibitor is 2-ketobenzothiazole 3, with a potent K(i) value of 0.2 nM and ca. Carbon 115-121 coagulation factor II, thrombin Homo sapiens 162-170 15780659-4 2005 When carbon and nitrogen are abundant, the phosphorylated Ure2p anchors the also phosphorylated Gln3p and Nil1p in the cytoplasm. Carbon 5-11 glutathione peroxidase Saccharomyces cerevisiae S288C 58-63 16028720-3 2005 The FA olefin (Z, C-9/C-10) of 2 was hydrogenated to produce a derivative possessing a hydroxy function (C-12) on a saturated C18 FA chain. Carbon 18-19 homeobox C10 Homo sapiens 22-26 16028720-3 2005 The FA olefin (Z, C-9/C-10) of 2 was hydrogenated to produce a derivative possessing a hydroxy function (C-12) on a saturated C18 FA chain. Carbon 18-19 Bardet-Biedl syndrome 9 Homo sapiens 126-129 15695443-0 2005 Tuber-specific cytosolic expression of a bacterial phosphoglucomutase in potato (Solanum tuberosum L.) dramatically alters carbon partitioning. Carbon 123-129 phosphoglucomutase Solanum tuberosum 51-69 15668256-5 2005 The enzyme can elongate acyl-chains containing 2-14 carbon atoms with malonyl moieties attached in thioester linkage to the human mitochondrial acyl carrier protein and is able to restore growth to the respiratory-deficient yeast mutant cem1 that lacks the endogenous mitochondrial beta-ketoacyl synthase and exhibits lowered lipoic acid levels. Carbon 52-58 3-oxoacyl-ACP synthase, mitochondrial Homo sapiens 282-304 15632177-6 2005 Thus, compounds with short alkyl spacers (2-3 carbon atoms) effectively blocked the interaction of fibroblast growth factor-1 (FGF-1) and lipoprotein lipase with heparin/HS, whereas longer chain spacers (7-10 carbon atoms) were required for optimal inhibition of FGF-2 and vascular endothelial growth factor binding. Carbon 46-52 fibroblast growth factor 1 Homo sapiens 99-125 15836376-2 2005 Six nonequivalent C atoms present in the molecule contribute to the C 1s photoemission spectrum. Carbon 18-19 complement C1s Homo sapiens 68-72 15632177-6 2005 Thus, compounds with short alkyl spacers (2-3 carbon atoms) effectively blocked the interaction of fibroblast growth factor-1 (FGF-1) and lipoprotein lipase with heparin/HS, whereas longer chain spacers (7-10 carbon atoms) were required for optimal inhibition of FGF-2 and vascular endothelial growth factor binding. Carbon 46-52 fibroblast growth factor 1 Homo sapiens 127-132 15632177-7 2005 This effect was most pronounced with the chemokine, interleukin-8, where alkyl-linked tetrameric cyclitols were essentially inactive unless a spacer of >7 carbon atoms was used. Carbon 158-164 C-X-C motif chemokine ligand 8 Homo sapiens 52-65 15701509-4 2005 A detailed NMR study indicates that the 10R (-)-trans-anti-[BP]G adduct undergoes a transition from a minor groove-binding alignment of the aromatic BP ring system in the unmethylated C-[BP]G sequence context, to an intercalative BP alignment with a concomitant displacement of the modified guanine residue into the minor groove in the methylated meC-[BP]G sequence context. Carbon 184-185 C-C motif chemokine ligand 28 Homo sapiens 347-350 15551062-17 2005 Thus, the different affinity of ADH and ALDH for alcohols and glycol ethers of different carbon-chain length may reflect the relative isoform expression in rat liver and skin. Carbon 89-95 aldo-keto reductase family 1 member A1 Rattus norvegicus 32-35 15674982-1 2005 Oxidative insertion of [Pd(PPh3)4] or [Ni(cod)2]/PPh3 into the C-Cl bond of various 2-chloroimidazolinium- and other -amidinium salts affords metal-diaminocarbene complexes in good to excellent yields. Carbon 63-64 caveolin 1 Homo sapiens 27-31 15674982-1 2005 Oxidative insertion of [Pd(PPh3)4] or [Ni(cod)2]/PPh3 into the C-Cl bond of various 2-chloroimidazolinium- and other -amidinium salts affords metal-diaminocarbene complexes in good to excellent yields. Carbon 63-64 caveolin 1 Homo sapiens 49-53 15695543-0 2005 Ultrafine carbon particles induce interleukin-8 gene transcription and p38 MAPK activation in normal human bronchial epithelial cells. Carbon 10-16 C-X-C motif chemokine ligand 8 Homo sapiens 34-47 15695543-0 2005 Ultrafine carbon particles induce interleukin-8 gene transcription and p38 MAPK activation in normal human bronchial epithelial cells. Carbon 10-16 mitogen-activated protein kinase 14 Homo sapiens 71-74 15695543-4 2005 Here, we report that carbonaceous ultrafine particles consisting of synthetic elemental carbon particles (UfCP) markedly increase the expression of IL-8 mRNA and protein in normal human bronchial epithelial (NHBE) cells. Carbon 21-27 C-X-C motif chemokine ligand 8 Homo sapiens 148-152 15611869-0 2005 Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae. Carbon 127-133 SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C 0-5 15755922-4 2005 PIS1 is regulated in response to carbon source and anaerobic growth conditions. Carbon 33-39 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 0-4 15755922-11 2005 A PIS1 promoter deletion study identified an upstream regulatory sequence element that was required for carbon source regulation located downstream of three previously defined upstream activation sequence elements. Carbon 104-110 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 2-6 15715465-1 2005 Fatty acid synthase (FAS) catalyzes the synthesis of palmitate from the sequential condensation of an acetyl primer with two carbon units added from malonyl-CoA. Carbon 125-131 fatty acid synthase Mus musculus 0-19 15748154-7 2005 An increase in retinal aspartate aminotransferase and lactate dehydrogenase activities was accompanied by altered levels of amino acids in neurons and glia after partial inhibition of glial metabolism, implying that short- and long-term up- and down-regulation of key metabolic enzymes occurs to supply carbon skeletons for retinal metabolism. Carbon 303-309 glutamic-oxaloacetic transaminase 2 Rattus norvegicus 23-49 15715465-1 2005 Fatty acid synthase (FAS) catalyzes the synthesis of palmitate from the sequential condensation of an acetyl primer with two carbon units added from malonyl-CoA. Carbon 125-131 fatty acid synthase Mus musculus 21-24 15715478-10 2005 Binding studies of one compound, 25o (C-14 radiolabeled), showed that it binds irreversibly to HER-2 protein in BT474 cells. Carbon 38-39 erb-b2 receptor tyrosine kinase 2 Homo sapiens 95-100 15664096-9 2005 Vitamins E and C and N-acetylcysteine blocked glucose- and fatty acid-induced NEP mRNA (p < or = 0.05). Carbon 15-16 membrane metalloendopeptidase Homo sapiens 78-81 15669071-9 2005 Computational models were generated for the situations before and after C-C bond formation in the active site of FucA. Carbon 0-1 alpha-L-fucosidase 1 Homo sapiens 113-117 15669071-9 2005 Computational models were generated for the situations before and after C-C bond formation in the active site of FucA. Carbon 72-73 alpha-L-fucosidase 1 Homo sapiens 113-117 15773496-0 2005 Comment on "addition of carbon sorbents to reduce PCB and PAH bioavailability in marine sediments: physicochemical tests". Carbon 24-30 pyruvate carboxylase Homo sapiens 50-53 15548527-1 2005 Aclacinomycin 10-hydroxylase is a methyltransferase homologue that catalyzes a S-adenosyl-L-methionine (AdoMet)-dependent hydroxylation of the C-10 carbon atom of 15-demethoxy-epsilon-rhodomycin, a step in the biosynthesis of the polyketide antibiotic beta-rhodomycin. Carbon 148-154 homeobox C10 Homo sapiens 143-147 15653338-4 2005 In fact, the importance for the A3 receptor-ligand interaction of both a strong acidic NH proton donor and a C=O proton acceptor at position-4, able to engage hydrogen-bonding interactions with specific sites on the A3 AR, has been confirmed. Carbon 109-110 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 Homo sapiens 32-34 15653338-4 2005 In fact, the importance for the A3 receptor-ligand interaction of both a strong acidic NH proton donor and a C=O proton acceptor at position-4, able to engage hydrogen-bonding interactions with specific sites on the A3 AR, has been confirmed. Carbon 109-110 adenosine A3 receptor Homo sapiens 216-221 15752473-1 2005 The preparation and electrochemical characterization of a carbon paste electrode modified with bis(N,N-piperidinedithiocarbamate)-mu-tris(N,N-piperidinedithiocarbamate)diruthenium(III) complex, alpha-[Ru2(Pip)5]Cl are described. Carbon 58-64 prolactin induced protein Homo sapiens 205-208 15672196-3 2005 Fe(III) is known to form a symmetrical 1:2 complex, but that complex is anionic due to binding of all four deprotonated amido groups; the unsymmetrical neutral Co(III) complex converts into a symmetrical anionic species only on heating for hours in aqueous base in the presence of activated carbon. Carbon 291-297 mitochondrially encoded cytochrome c oxidase III Homo sapiens 3-6 15672196-3 2005 Fe(III) is known to form a symmetrical 1:2 complex, but that complex is anionic due to binding of all four deprotonated amido groups; the unsymmetrical neutral Co(III) complex converts into a symmetrical anionic species only on heating for hours in aqueous base in the presence of activated carbon. Carbon 291-297 mitochondrially encoded cytochrome c oxidase III Homo sapiens 160-167 15698217-0 2005 Band filling and interband scattering effects in MgB2: carbon versus aluminum doping. Carbon 55-61 secretoglobin family 2A member 1 Homo sapiens 49-53 15671219-2 2005 SHMT is a major source of one-carbon units for cellular metabolism, but its sensitivity to various degrees of altered vitamin B-6 nutritional status has not been determined. Carbon 30-36 serine hydroxymethyltransferase 1 Rattus norvegicus 0-4 15671219-9 2005 Overall these results demonstrate the potential for disruption of SHMT-mediated one-carbon metabolism by inadequate vitamin B-6 intake. Carbon 84-90 serine hydroxymethyltransferase 1 Rattus norvegicus 66-70 15780499-5 2005 Recent studies in breast cancer cells have revealed a bi-directional connection between Her-2/neu and fatty acid synthase (FAS), a major lipogenic enzyme catalyzing the synthesis of long-chain saturated fatty acids from the 2-carbon donors malonyl-CoA and acetyl-CoA. Carbon 226-232 erb-b2 receptor tyrosine kinase 2 Homo sapiens 88-97 15627369-4 2005 on the other hand, for Mn(ii) and Fe(ii) ions, L(Cu) shows a 2-carboxylate bridging mode to form an another 1-d assembly with a repeating motif of [-M-O-C-O-CU-O-C-O-]: [ML(Cu)(H(2)O)(4)](N)() (M = Mn (7), Fe (8)). Carbon 49-50 mitochondrially encoded cytochrome c oxidase II Homo sapiens 26-28 15627369-4 2005 on the other hand, for Mn(ii) and Fe(ii) ions, L(Cu) shows a 2-carboxylate bridging mode to form an another 1-d assembly with a repeating motif of [-M-O-C-O-CU-O-C-O-]: [ML(Cu)(H(2)O)(4)](N)() (M = Mn (7), Fe (8)). Carbon 49-50 mitochondrially encoded cytochrome c oxidase II Homo sapiens 37-39 15627369-4 2005 on the other hand, for Mn(ii) and Fe(ii) ions, L(Cu) shows a 2-carboxylate bridging mode to form an another 1-d assembly with a repeating motif of [-M-O-C-O-CU-O-C-O-]: [ML(Cu)(H(2)O)(4)](N)() (M = Mn (7), Fe (8)). Carbon 153-154 mitochondrially encoded cytochrome c oxidase II Homo sapiens 26-28 15627369-4 2005 on the other hand, for Mn(ii) and Fe(ii) ions, L(Cu) shows a 2-carboxylate bridging mode to form an another 1-d assembly with a repeating motif of [-M-O-C-O-CU-O-C-O-]: [ML(Cu)(H(2)O)(4)](N)() (M = Mn (7), Fe (8)). Carbon 153-154 mitochondrially encoded cytochrome c oxidase II Homo sapiens 37-39 15631439-1 2005 Sc2[eta2(mu2-C,O)], the first homoleptic dinuclear metal carbonyl with an unprecedented bridging and side-on-bonded CO, generated from the reaction of laser-ablated Sc atoms with CO in a solid argon matrix, exhibits an unusually low C-O stretching frequency at 1193.4 cm-1, characteristic of an anomalously weakened C-O bond. Carbon 13-14 trans-2,3-enoyl-CoA reductase Homo sapiens 0-3 15631439-1 2005 Sc2[eta2(mu2-C,O)], the first homoleptic dinuclear metal carbonyl with an unprecedented bridging and side-on-bonded CO, generated from the reaction of laser-ablated Sc atoms with CO in a solid argon matrix, exhibits an unusually low C-O stretching frequency at 1193.4 cm-1, characteristic of an anomalously weakened C-O bond. Carbon 116-117 trans-2,3-enoyl-CoA reductase Homo sapiens 0-3 16197314-2 2005 Even though depletion of B12, a common B-vitamin deficiency in the elderly, has not often been invoked as a causative factor in carcinogenesis, a recent animal study demonstrated that a B12-deficient diet, which was of insufficient severity to cause anemia or illness, disturbed normal homeostasis of one-carbon metabolism in the colonic mucosa and resulted in diminished genomic DNA methylation and increased uracil misincorporation in DNA, both of which are purported mechanisms for one-carbon metabolism-related colonic carcinogenesis. Carbon 305-311 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 186-189 16197314-2 2005 Even though depletion of B12, a common B-vitamin deficiency in the elderly, has not often been invoked as a causative factor in carcinogenesis, a recent animal study demonstrated that a B12-deficient diet, which was of insufficient severity to cause anemia or illness, disturbed normal homeostasis of one-carbon metabolism in the colonic mucosa and resulted in diminished genomic DNA methylation and increased uracil misincorporation in DNA, both of which are purported mechanisms for one-carbon metabolism-related colonic carcinogenesis. Carbon 489-495 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 186-189 15671130-9 2005 Folate and vitamin B12 are major determinants of one-carbon metabolism, in which S-adenosylmethionine (SAM) is formed. Carbon 53-59 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 19-22 16989156-6 2005 The distribution of TGF-beta1 genotypes in codon 10 was as follows in COPD group: T/C--50%, T/T--25% and C/C--25% in control group: 45%, 42% and 13% respectively. Carbon 70-71 transforming growth factor beta 1 Homo sapiens 20-29 16989156-6 2005 The distribution of TGF-beta1 genotypes in codon 10 was as follows in COPD group: T/C--50%, T/T--25% and C/C--25% in control group: 45%, 42% and 13% respectively. Carbon 84-85 transforming growth factor beta 1 Homo sapiens 20-29 15606119-1 2004 [reaction: see text] The construction of chiral carbon centers via the first catalytic asymmetric alkynylation of prochiral CH2 groups was developed by using a copper-catalyzed double activation of sp3 and sp C-H bonds. Carbon 48-54 Sp3 transcription factor Homo sapiens 198-201 15697989-2 2004 The core of the defect is a double layer of threefold coordinated sp2 carbon atoms embedded in the sp3 diamond matrix. Carbon 70-76 Sp2 transcription factor Homo sapiens 66-69 15697989-2 2004 The core of the defect is a double layer of threefold coordinated sp2 carbon atoms embedded in the sp3 diamond matrix. Carbon 70-76 Sp3 transcription factor Homo sapiens 99-102 15612815-4 2004 Adsorption with activated carbon, together with anion exchange and affinity chromatography, led to the isolation of a heterodimeric milk-clotting proteinase consisting of 30- and 15-kDa subunits. Carbon 26-32 endogenous retrovirus group K member 25 Homo sapiens 146-156 15606119-1 2004 [reaction: see text] The construction of chiral carbon centers via the first catalytic asymmetric alkynylation of prochiral CH2 groups was developed by using a copper-catalyzed double activation of sp3 and sp C-H bonds. Carbon 48-54 surfactant protein C Homo sapiens 206-210 15684786-8 2004 Hepatic IL-6 levels increased in the I/R group compared to the C group (4.17 +/- 0.31 pg/mg protein vs. 2.93 +/- 0.20 pg/mg, P < 0.05). Carbon 63-64 interleukin 6 Rattus norvegicus 8-12 15634132-5 2004 When n=5 or 7, the longest branch is connected to the central sp2 carbon in a nonlinear manner. Carbon 66-72 Sp2 transcription factor Homo sapiens 62-65 15590831-13 2004 Using a heterozygous DYN1/dyn1 strain in which the remaining copy was controlled by the regulatable MAL2 promoter, we could switch between wild-type and mutant phenotypes depending on the carbon source, indicating that the observed mutant phenotypes were solely due to deletion of DYN1. Carbon 188-194 dynein heavy chain Saccharomyces cerevisiae S288C 21-25 15590831-13 2004 Using a heterozygous DYN1/dyn1 strain in which the remaining copy was controlled by the regulatable MAL2 promoter, we could switch between wild-type and mutant phenotypes depending on the carbon source, indicating that the observed mutant phenotypes were solely due to deletion of DYN1. Carbon 188-194 dynein heavy chain Saccharomyces cerevisiae S288C 26-30 15520229-6 2004 We show that a second threshold is required together with the Cln3/Far1 threshold for carbon source modulation of Ps. Carbon 86-92 cyclin CLN3 Saccharomyces cerevisiae S288C 62-66 15337744-4 2004 Therefore, a ligand of a size equivalent to more than approximately 4 carbon atoms could only bind in the LBP, if ERRalpha would undergo a major conformational change (in particular the ligand would displace H12 from its agonist position). Carbon 70-76 estrogen related receptor alpha Homo sapiens 114-122 15563617-0 2004 The role of plastocyanin in the adjustment of the photosynthetic electron transport to the carbon metabolism in tobacco. Carbon 91-97 plastocyanin Nicotiana tabacum 12-24 15543751-0 2004 Addition of carbon sorbents to reduce PCB and PAH bioavailability in marine sediments: physicochemical tests. Carbon 12-18 pyruvate carboxylase Homo sapiens 38-41 15747308-6 2004 An emphasis was placed on a resin only cartridge as previous studies suggested that some patients may be sensitive to the activated carbon, particularly if they are taking ACE inhibitors. Carbon 132-138 angiotensin I converting enzyme Homo sapiens 172-175 15543331-0 2004 Fibrinogen adsorption and platelet adhesion to metal and carbon coatings. Carbon 57-63 fibrinogen beta chain Homo sapiens 0-10 15543331-3 2004 It has been shown that the adsorption of fibrinogen to metal and carbon coatings and its post-adsorptive transition are dependent on both the material properties and the fibrinogen environment. Carbon 65-71 fibrinogen beta chain Homo sapiens 41-51 15543331-3 2004 It has been shown that the adsorption of fibrinogen to metal and carbon coatings and its post-adsorptive transition are dependent on both the material properties and the fibrinogen environment. Carbon 65-71 fibrinogen beta chain Homo sapiens 170-180 15543331-5 2004 Both carbon coatings adsorb much greater amount of fibrinogen from plasma, and fibrinogen retention by carbon surfaces is also greater than by metal surfaces. Carbon 5-11 fibrinogen beta chain Homo sapiens 51-61 15543331-5 2004 Both carbon coatings adsorb much greater amount of fibrinogen from plasma, and fibrinogen retention by carbon surfaces is also greater than by metal surfaces. Carbon 103-109 fibrinogen beta chain Homo sapiens 79-89 15466158-5 2004 Sfp1 and Sch9 are required for carbon-source modulation of cell size and are regulated at the level of nuclear localization and abundance, respectively. Carbon 31-37 serine/threonine protein kinase SCH9 Saccharomyces cerevisiae S288C 9-13 15551048-6 2004 Combined with classical biochemistry, these techniques show that the beta cell is uniquely poised, thanks to the expression of low levels of lactate dehydrogenase and plasma membrane lactate/monocarboxylate transporters, to channel glucose carbons towards oxidative metabolism, ATP synthesis and inhibition of AMP-activated protein kinase, a newly defined regulator of insulin release. Carbon 240-247 insulin Homo sapiens 369-376 15554689-6 2004 Five aligned thrombin cocrystals with an average core alpha-carbon RMSD of 0.7 A gave three-dimensional pharmacophore descriptors with an average RMSD of 1.1 A. Carbon 60-66 coagulation factor II, thrombin Homo sapiens 13-21 15543751-4 2004 Sediment treated with 3.4 wt % activated carbon showed 92% and 84% reductions in aqueous equilibrium PCB and PAH concentrations, 77% and 83% reductions in PCB and PAH uptake by semipermeable membrane devices (SPMD), respectively, and reductions in PCB flux to overlying water in quiescent systems up to 89%. Carbon 41-47 pyruvate carboxylase Homo sapiens 101-104 15543751-4 2004 Sediment treated with 3.4 wt % activated carbon showed 92% and 84% reductions in aqueous equilibrium PCB and PAH concentrations, 77% and 83% reductions in PCB and PAH uptake by semipermeable membrane devices (SPMD), respectively, and reductions in PCB flux to overlying water in quiescent systems up to 89%. Carbon 41-47 pyruvate carboxylase Homo sapiens 155-158 15543751-4 2004 Sediment treated with 3.4 wt % activated carbon showed 92% and 84% reductions in aqueous equilibrium PCB and PAH concentrations, 77% and 83% reductions in PCB and PAH uptake by semipermeable membrane devices (SPMD), respectively, and reductions in PCB flux to overlying water in quiescent systems up to 89%. Carbon 41-47 pyruvate carboxylase Homo sapiens 155-158 15453749-0 2004 Mechanism of substitution reaction on sp2-carbon center with lithium organocuprate. Carbon 42-48 Sp2 transcription factor Homo sapiens 38-41 15247244-1 2004 Hydroxymethylglutaryl-CoA synthase-catalyzed condensation of acetyl-CoA with acetoacetyl-CoA requires enolization/carbanion formation from the acetyl C-2 methyl group prior to formation of a new carbon-carbon bond. Carbon 195-201 AT695_RS04545 Staphylococcus aureus 0-34 15491124-1 2004 The bifunctional enzyme carbon monoxide dehydrogenase/acetyl-coenzyme A (CoA) synthase (CODH/ACS) is a key enzyme in the Wood-Ljungdahl pathway of carbon fixation. Carbon 24-30 Coenzyme A synthase Homo sapiens 40-86 15258255-11 2004 Taken together, our results show that exposure to C-1305 is accompanied by the formation of low levels of potent cleavable complexes that are selectively toxic toward tumor cells with defective p53 function. Carbon 50-51 tumor protein p53 Homo sapiens 194-197 15553218-5 2004 By EPR spectroscopy, a carbon-centered radical from the 1,4-DHP was intercepted with N-tert-butylamine-alpha-phenylnitrone (PBN), as the intermediate for the reaction with peroxynitrite. Carbon 23-29 dihydropyrimidinase Homo sapiens 60-63 15252058-4 2004 Analysis of these null mutants shows that Atc1p is localized in the cell wall and is required for growth on trehalose as a carbon source. Carbon 123-129 Atc1p Saccharomyces cerevisiae S288C 42-47 15375610-9 2004 The complete human Osteocalcin promoter and the bone-sialoprotein promoter were partially induced by vitamin D3 or C respectively while the pAd.3r-luc activity could be shut down by doxycyclin. Carbon 115-116 bone gamma-carboxyglutamate protein Homo sapiens 19-30 15247244-1 2004 Hydroxymethylglutaryl-CoA synthase-catalyzed condensation of acetyl-CoA with acetoacetyl-CoA requires enolization/carbanion formation from the acetyl C-2 methyl group prior to formation of a new carbon-carbon bond. Carbon 202-208 AT695_RS04545 Staphylococcus aureus 0-34 15472418-1 2004 In cross-sectional studies, low levels of folate and B12 have been shown to be associated with cognitive decline and dementia Evidence for the putative role of folate, vitamin B12 in neurocognitive and other neurological functions comes from reported cases of severe vitamin deficiencies, particularly pernicious anemia, and homozygous defects in genes that encode for enzymes of one-carbon metabolism. Carbon 384-390 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 53-56 15342116-5 2004 Both the expression pattern and metabolite rescue support the proposal that mitochondrial NMDMC provides one-carbon units for purine synthesis during embryogenesis. Carbon 109-115 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase Mus musculus 90-95 15166004-2 2004 We postulated that intraduodenal administration of lauric acid (12 carbon atoms; C12) would suppress appetite, modulate antropyloroduodenal pressure waves (PWs), and stimulate the release of cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1) more than an identical dose of decanoic acid (10 carbon atoms; C10). Carbon 67-73 cholecystokinin Homo sapiens 191-206 15166004-2 2004 We postulated that intraduodenal administration of lauric acid (12 carbon atoms; C12) would suppress appetite, modulate antropyloroduodenal pressure waves (PWs), and stimulate the release of cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1) more than an identical dose of decanoic acid (10 carbon atoms; C10). Carbon 298-304 cholecystokinin Homo sapiens 208-211 15377163-1 2004 The covalent binding of 4-[(13)C]- and 5-[(13)C]-5-chloro-2-methylisothiazol-3-one (MCI) toward human serum albumin (HSA) was followed by (13)C and (1)H[(13)C] NMR spectroscopy. Carbon 30-32 albumin Homo sapiens 102-121 15309370-2 2004 It is based on the enhanced oxidation of lovastatin at a novel acetylene black-dihexadecyl hydrogen phosphate composite-modified glassy-carbon electrode (AB-DHP/GCE) in the presence of Triton X-100. Carbon 136-142 dihydropyrimidinase Homo sapiens 157-160 15669763-0 2004 Biomimetic oxidation of unactivated carbons in steroids by a model of cytochrome P-450, oxorutheniumporphyrinate complex. Carbon 36-43 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 70-86 15669763-1 2004 Biomimetic oxidation of unactivated carbons for structurally different steroids was studied with a model of cytochrome P-450, oxorutheniumporphyrinate complex, which is generated in situ by 2,6-dichloropyridine N-oxide as an oxygen donor and (5,10,15,20-tetramesitylporphyrinate) ruthenium(II) carbonyl complex and HBr as catalysts. Carbon 36-43 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 108-124 15225690-1 2004 The synthesis and biological activity of novel CD-ring modified analogues of 22-oxa-1alpha,25-dihydroxyvitamin D(3), lacking the D-ring and featuring a connection between C-12 and C-21 (cis-perhydrindane CE-ring analogues), is described. Carbon 47-48 TBL1X/Y related 1 Homo sapiens 180-184 15197185-10 2004 Finally we demonstrate that S2 cells transfected with Cyp306a1 convert ketodiol to ketotriol via carbon 25 hydroxylation. Carbon 97-103 phantom Drosophila melanogaster 54-62 18969556-10 2004 An acidic silica column combined with an activated carbon column allows the separation of PCDD/F and dioxin-like PCB in two different fractions, PBB 169 is completely eluted in the dioxin fraction and PBB 77 is distributed between the PCB and dioxin fraction. Carbon 51-57 pyruvate carboxylase Homo sapiens 113-116 15297675-3 2004 We sequenced three candidate genes (ABCA1, APOA1, and LCAT) that cause Mendelian forms of low HDL-C levels in individuals from a population-based study. Carbon 97-99 apolipoprotein A1 Homo sapiens 43-48 15362951-1 2004 A new UV filter, the 1-(4-tert-butylphenyl)-2-decanyl-3-(4"-methoxyphenyl)-propane-1,3-dione, called C10-DBM, was prepared by grafting a 10-carbon aliphatic chain to the alpha-carbonyl position of 4-tert-butyl-4"-methoxydibenzoylmethane (BM-DBM), a well-known and often used UV filter. Carbon 140-146 homeobox C10 Homo sapiens 101-108 15349513-5 2004 An outline of the proposed mechanism by which mycotoxins disrupt or interfere with the normal functions of vitamin B12 on one-carbon metabolism is proposed. Carbon 126-132 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 115-118 15349513-6 2004 The overall functions of vitamin B12 as a source of coenzymes, in intracellular recycling of methionine, in methionine synthase reaction, in the prevention of chromosome breakage, in methylation, and in maintaining a one-carbon metabolic balance are reviewed. Carbon 221-227 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 33-36 15349513-8 2004 By implication and derivation, it is likely that the interruption of the structure and function of vitamin B12 would in turn interfere with the one-carbon metabolism leading to the neurological manifestations. Carbon 148-154 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 107-110 15137908-1 2004 Fructosamine 3-kinase (FN3K), an enzyme initially identified in erythrocytes, catalyses the phosphorylation of fructosamines on their third carbon, leading to their destabilization and their removal from protein. Carbon 140-146 fructosamine 3 kinase Homo sapiens 0-21 15137908-1 2004 Fructosamine 3-kinase (FN3K), an enzyme initially identified in erythrocytes, catalyses the phosphorylation of fructosamines on their third carbon, leading to their destabilization and their removal from protein. Carbon 140-146 fructosamine 3 kinase Homo sapiens 23-27 15248254-2 2004 In the first series (1-3) the coupling between a hydrogen, bonded to an sp3 carbon, and an sp2 carbon is treated; the second series (4-6) deals with the coupling between a hydrogen, bonded to an sp3 carbon, and an sp3 carbon. Carbon 95-101 Sp2 transcription factor Homo sapiens 91-94 16036753-0 2004 Expression of C-reactive protein in human lung epithelial cells and upregulation by cytokines and carbon particles. Carbon 98-104 C-reactive protein Homo sapiens 14-32 15208340-7 2004 Aside from the sulphur-specific regulation, the induction of SULTR1;1 and SULTR1;2 high-affinity sulphate transporters by sulphur limitation was dependent on the supply of carbon and nitrogen. Carbon 172-178 sulfate transporter 1;1 Arabidopsis thaliana 61-69 15248254-2 2004 In the first series (1-3) the coupling between a hydrogen, bonded to an sp3 carbon, and an sp2 carbon is treated; the second series (4-6) deals with the coupling between a hydrogen, bonded to an sp3 carbon, and an sp3 carbon. Carbon 95-101 Sp2 transcription factor Homo sapiens 91-94 15248254-2 2004 In the first series (1-3) the coupling between a hydrogen, bonded to an sp3 carbon, and an sp2 carbon is treated; the second series (4-6) deals with the coupling between a hydrogen, bonded to an sp3 carbon, and an sp3 carbon. Carbon 95-101 Sp2 transcription factor Homo sapiens 91-94 15225598-8 2004 Post-radiation addition of ascorbate and RibCys also affected the quality of CD59(-) mutations induced by carbon-ions. Carbon 106-112 CD59 molecule (CD59 blood group) Homo sapiens 77-81 15228330-5 2004 Using a solution of angiotensin I, the carbon fiber emitter in 75-microm-i.d. Carbon 39-45 angiotensinogen Homo sapiens 20-33 15205420-0 2004 Presence of a novel phosphopentomutase and a 2-deoxyribose 5-phosphate aldolase reveals a metabolic link between pentoses and central carbon metabolism in the hyperthermophilic archaeon Thermococcus kodakaraensis. Carbon 134-140 deoxyribose-phosphate aldolase Homo sapiens 45-79 14967525-0 2004 Preparation of novel mesoporous carbons for the adsorption of an inflammatory cytokine (IL-1 beta). Carbon 32-39 interleukin 1 beta Homo sapiens 88-97 14967525-4 2004 The highest adsorption value of IL-1 beta was 150 ng g(-1) for a mesoporous carbon with surface area around 900 m(2)g(-1) and pore volume around 1.3 cm(3)g(-1). Carbon 76-82 interleukin 1 beta Homo sapiens 32-41 15205420-1 2004 Numerous bacteria and mammalian cells harbor two enzymes, phosphopentomutase (PPM) and 2-deoxyribose 5-phosphate aldolase (DERA), involved in the interconversion between nucleosides and central carbon metabolism. Carbon 194-200 deoxyribose-phosphate aldolase Homo sapiens 87-121 15205420-1 2004 Numerous bacteria and mammalian cells harbor two enzymes, phosphopentomutase (PPM) and 2-deoxyribose 5-phosphate aldolase (DERA), involved in the interconversion between nucleosides and central carbon metabolism. Carbon 194-200 deoxyribose-phosphate aldolase Homo sapiens 123-127 15205420-9 2004 Our results clearly indicate the presence of a metabolic link between pentoses and central carbon metabolism in T. kodakaraensis, providing an alternative route for pentose biosynthesis through the functions of DERA and a structurally novel PPM. Carbon 91-97 deoxyribose-phosphate aldolase Homo sapiens 211-215 15110290-6 2004 Following the optimisation of the paste composition, PPO-based carbon paste biosensors were prepared and presented excellent analytical properties toward catechol detection with a sensitivity of 4.7 A M(-1) cm(-2) and a response time lower than 20 s. The resulting biosensors were applied to the determination of polyphenolic compounds (e.g., epicatechin and ferulic acid). Carbon 63-69 protoporphyrinogen oxidase Homo sapiens 53-56 15180418-4 2004 Consistent with the idea that electron-withdrawing R makes platinum(II) more resistant to oxidation (i.e., a proton on Pt), and thus less Bronsted basic, the (1)J(PtH) coupling constant falls in the series R = Me (90 Hz), R = C(6)H(5) (86 Hz), and R = C(6)F(5) (63 Hz). Carbon 0-1 parathyroid hormone Homo sapiens 163-166 15180418-4 2004 Consistent with the idea that electron-withdrawing R makes platinum(II) more resistant to oxidation (i.e., a proton on Pt), and thus less Bronsted basic, the (1)J(PtH) coupling constant falls in the series R = Me (90 Hz), R = C(6)H(5) (86 Hz), and R = C(6)F(5) (63 Hz). Carbon 226-227 parathyroid hormone Homo sapiens 163-166 15184173-6 2004 Overexpression of the GRE3 and ScXYL2 genes in the S. cerevisiae CEN.PK2 strain resulted in a growth rate of 0.01 g of cell dry mass liter(-1) h(-1) and a xylitol yield of 55% when xylose was the main carbon source. Carbon 201-207 trifunctional aldehyde reductase/xylose reductase/glucose 1-dehydrogenase (NADP(+)) Saccharomyces cerevisiae S288C 22-26 15173561-5 2004 Further studies reported here were designed toward understanding carbon metabolism in the sse1 mutant. Carbon 65-71 shrunken seed protein (SSE1) Arabidopsis thaliana 90-94 15147343-10 2004 The levels of interleukin (IL)-6, IL-12p70, interferon-gamma and tumour necrosis factor-alpha were significantly higher in poly I:C-injected thymectomized mice compared to PBS-injected neonatal thymectomized mice (P < 0.05). Carbon 130-131 interferon gamma Mus musculus 44-93 15197733-7 2004 This is a first report on the role of the C. albicans essential gene BMH1 as a negative regulator of the utilization of secondary carbon source in yeast, which further substantiates the involvement of 14-3-3 proteins in diverse functions. Carbon 130-136 14-3-3 family protein BMH1 Saccharomyces cerevisiae S288C 69-73 15153187-0 2004 Carbon partitioning in leaves and tubers of transgenic potato plants with reduced activity of fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Carbon 0-6 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Solanum tuberosum 94-151 15161352-1 2004 The accumulation of the cell cycle regulators TP53 and CDKN1A (p21/CIP1/WAF1) was investigated after exposure to X rays and carbon ions (170 keV microm(-1)) and xenon, bismuth and uranium ions (8900-15,000 keV microm(-1)) in normal human fibroblasts. Carbon 124-130 tumor protein p53 Homo sapiens 46-50 15161352-1 2004 The accumulation of the cell cycle regulators TP53 and CDKN1A (p21/CIP1/WAF1) was investigated after exposure to X rays and carbon ions (170 keV microm(-1)) and xenon, bismuth and uranium ions (8900-15,000 keV microm(-1)) in normal human fibroblasts. Carbon 124-130 cyclin dependent kinase inhibitor 1A Homo sapiens 55-61 15161352-1 2004 The accumulation of the cell cycle regulators TP53 and CDKN1A (p21/CIP1/WAF1) was investigated after exposure to X rays and carbon ions (170 keV microm(-1)) and xenon, bismuth and uranium ions (8900-15,000 keV microm(-1)) in normal human fibroblasts. Carbon 124-130 cyclin dependent kinase inhibitor 1A Homo sapiens 63-66 15154797-20 2004 The rearrangement of trans-HCOH (carbon bound) to CH(2)O (oxygen bound) on ZnO(0001) was calculated to be the overall barrier of the MSR reaction. Carbon 33-39 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 133-136 15122911-7 2004 The conversion of nitroxide radicals to the 2,2-DMPy products by CYP3A4 or hemin was accompanied by the generation of acetone in incubations, providing evidence that the three-carbon unit from 2,2,6,6-TMPi was lost as acetone. Carbon 176-182 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 65-71 15147199-5 2004 Importantly, >30% of the identified genes (71 genes) were found to be associated with carbon (C) and nitrogen (N) metabolism and transport, thereby suggesting that Bmh1/2p may play a major role in the regulation of C/N-responsive cellular processes. Carbon 89-95 14-3-3 family protein BMH1 Saccharomyces cerevisiae S288C 167-174 15147199-5 2004 Importantly, >30% of the identified genes (71 genes) were found to be associated with carbon (C) and nitrogen (N) metabolism and transport, thereby suggesting that Bmh1/2p may play a major role in the regulation of C/N-responsive cellular processes. Carbon 97-98 14-3-3 family protein BMH1 Saccharomyces cerevisiae S288C 167-174 15245311-0 2004 Systematic effects of carbon doping on the superconducting properties of Mg(B1-xCx)(2). Carbon 22-28 secretoglobin family 2A member 2 Homo sapiens 73-78 15084118-8 2004 To validate the AGRP-mMC4R model complex presented herein from a ligand perspective, we generated nine chimeric peptide ligands based on a modified antagonist template of the hAGRP(109-118) (Tyr-c[Asp-Arg-Phe-Phe-Asn-Ala-Phe-Dpr]-Tyr-NH(2)). Carbon 33-34 agouti related neuropeptide Mus musculus 16-20 15100179-4 2004 Docking experiments with a homology model of AST IV revealed three amino acid residues, Phe77, Phe138, and Tyr236, that may potentially be important for interactions with substituents on the chiral carbon of a benzylic alcohol serving as a sulfuryl acceptor, thereby imparting stereoselectivity. Carbon 198-204 sulfotransferase family 1A member 1 Rattus norvegicus 45-51 15053620-1 2004 Carbon-halogen bond dissociation rates for a series of aryl halide radical anions (ArX-: X = Cl, Br) in NMP were measured at room temperature by pulse radiolysis with 10-11 s time resolution. Carbon 0-6 aristaless related homeobox Homo sapiens 83-86 15069189-2 2004 The process features a one-pot tandem aldol reaction catalyzed by a deoxyribose-5-phosphate aldolase (DERA) to form a 6-carbon intermediate with installation of two stereogenic centers from 2-carbon starting materials. Carbon 120-126 deoxyribose-phosphate aldolase Homo sapiens 68-100 15069189-2 2004 The process features a one-pot tandem aldol reaction catalyzed by a deoxyribose-5-phosphate aldolase (DERA) to form a 6-carbon intermediate with installation of two stereogenic centers from 2-carbon starting materials. Carbon 120-126 deoxyribose-phosphate aldolase Homo sapiens 102-106 15069189-2 2004 The process features a one-pot tandem aldol reaction catalyzed by a deoxyribose-5-phosphate aldolase (DERA) to form a 6-carbon intermediate with installation of two stereogenic centers from 2-carbon starting materials. Carbon 192-198 deoxyribose-phosphate aldolase Homo sapiens 68-100 15069189-2 2004 The process features a one-pot tandem aldol reaction catalyzed by a deoxyribose-5-phosphate aldolase (DERA) to form a 6-carbon intermediate with installation of two stereogenic centers from 2-carbon starting materials. Carbon 192-198 deoxyribose-phosphate aldolase Homo sapiens 102-106 14990987-9 2004 In both androgen-independent, rapidly growing C-81 and ErbB-2 cDNA-transfected C-33 cells, p52(Shc) was hyperphosphorylated at Tyr317 (Y317). Carbon 46-47 nuclear factor kappa B subunit 2 Homo sapiens 91-94 15296234-7 2004 The experimental data allow the conclusion that the observed nanotube diameter is based on materials properties of sp2-bonded carbon/graphene sheets, on individual properties of the catalyst elements, and on additional kinetic components from temperature and pressure changes. Carbon 126-132 Sp2 transcription factor Homo sapiens 115-118 15071205-1 2004 The title compound, [Co(C(5)H(11))(C(62)H(88)N(13)O(14)P)].0.385C(3)H(6)O.12.650H(2)O, contains the isoamyl (3-methylbutyl) anion bonded to the Co(III) ion through a C atom. Carbon 21-22 mitochondrially encoded cytochrome c oxidase III Homo sapiens 144-151 15112828-7 2004 Compared to the distribution of carbons in TNT as 14% sp3- and 86% sp2-hybridized, the precipitate fraction from hydrolysis of unlabeled TNT contained 33% sp3- and 67% sp2-hybridized carbons. Carbon 183-190 Sp2 transcription factor Homo sapiens 168-171 15835161-0 2004 Structural characteristics of activated carbons and ibuprofen adsorption affected by bovine serum albumin. Carbon 40-47 albumin Homo sapiens 92-105 15040733-1 2004 We describe an efficient solid-phase synthesis of clavulones via the sequential coupling of the alpha- and omega-chains, involving two separate carbon-carbon bond-forming steps. Carbon 144-150 Fc gamma receptor and transporter Homo sapiens 96-119 15040733-1 2004 We describe an efficient solid-phase synthesis of clavulones via the sequential coupling of the alpha- and omega-chains, involving two separate carbon-carbon bond-forming steps. Carbon 151-157 Fc gamma receptor and transporter Homo sapiens 96-119 15835161-3 2004 Adsorption of ibuprofen [2-(4-isobutylphenyl)propionic acid] on activated carbons possessing different pore size distributions in protein-free and bovine serum albumin (BSA)-containing aqueous solutions reveals the importance of the contribution of mesopores to the total porosity of adsorbents. Carbon 74-81 albumin Homo sapiens 154-167 14711823-3 2004 Escherichia coli has a single ACS, FadD, that is essential for growth when fatty acids are the sole carbon and energy source. Carbon 100-106 acyl-CoA synthetase long-chain family member 1 Rattus norvegicus 30-33 14722105-5 2004 Thrombin generation was also inhibited by glucosylsphingosine, lysosphingomyelin, phytosphingosine, and primary alkylamines with >10 carbons. Carbon 136-143 coagulation factor II, thrombin Homo sapiens 0-8 14711823-7 2004 In the fadD background, the rat ACS isoforms 1, 2, 3, 4 and 5 oxidized [(14)C]oleate at 5 to 25% of the wild type levels, but only ACS5 restored growth on oleate as the sole carbon source. Carbon 174-180 acyl-CoA synthetase long-chain family member 1 Rattus norvegicus 32-35 14995181-1 2004 An effective method for cis-stereoselective attachment of functionalized alkenyl appendages to sp3 carbon is reported. Carbon 99-105 Sp3 transcription factor Homo sapiens 95-98 15128097-1 2004 The aim of this study was to develop a rapid method to measure alpha-fetoprotein (AFP) in human serum by use of one-step sandwich enzyme-linked immunosorbent assay (ELISA)-based immunobiosensor with disposable screen-printed carbon electrode technology. Carbon 225-231 alpha fetoprotein Homo sapiens 63-80 15128097-1 2004 The aim of this study was to develop a rapid method to measure alpha-fetoprotein (AFP) in human serum by use of one-step sandwich enzyme-linked immunosorbent assay (ELISA)-based immunobiosensor with disposable screen-printed carbon electrode technology. Carbon 225-231 alpha fetoprotein Homo sapiens 82-85 14735577-2 2004 The carbonium ion t-Bu(+) that is normally sandwiched between the water clusters was found to be absent, such that a Cbond;O covalent bond was formed in the intermediate (Int1) after heterolysis. Carbon 4-13 Wnt family member 1 Homo sapiens 171-175 14685767-0 2004 Transcriptional activators Cat8 and Sip4 discriminate between sequence variants of the carbon source-responsive promoter element in the yeast Saccharomyces cerevisiae. Carbon 87-93 Sip4p Saccharomyces cerevisiae S288C 36-40 15268546-1 2004 Since their discovery in 1990, the study of sp2 bonded carbon nanotubes has grown into a field of research in it"s own right; however the development of the sp3 analog, diamond nanowires, has been slow. Carbon 55-61 Sp2 transcription factor Homo sapiens 44-47 15114510-2 2004 The (-)-epicatechin and (+)-catechin derivatives comprised of aromatic groups increased activity and derivatives with acyl chain groups of carbon atoms in the close vicinity of C8 to C10 showed strong antimicrobial activity (MIC = 2 - 8 microg/ml) against Gram-positive bacteria and weak activity against fungi. Carbon 139-145 homeobox C10 Homo sapiens 183-186 15114510-2 2004 The (-)-epicatechin and (+)-catechin derivatives comprised of aromatic groups increased activity and derivatives with acyl chain groups of carbon atoms in the close vicinity of C8 to C10 showed strong antimicrobial activity (MIC = 2 - 8 microg/ml) against Gram-positive bacteria and weak activity against fungi. Carbon 139-145 CD99 molecule (Xg blood group) Homo sapiens 225-232 14961647-3 2004 The (1-->5)-linked amides of 2,3-dehydroneuraminic acid were further subjected to hydrogenation giving a third series of oligomers with a beta-hydrido substituent at the anomeric carbon. Carbon 182-188 amyloid beta precursor protein Homo sapiens 139-145 14748719-4 2004 Moreover, recent studies have provided strong evidence that this Delta6-desaturase also acts on 24-carbon PUFAs of both the n-6 and n-3 series. Carbon 99-105 fatty acid desaturase 2 Homo sapiens 71-82 14746449-2 2004 The C13-C21 fragment was prepared from two simple starting materials that were joined in a catalytic alkyne-epoxide fragment coupling operation, whereas an intramolecular aldehyde-alkyne reductive coupling simultaneously formed the final carbon-carbon bond of the macrocycle and established the C13 carbinol configuration with complete selectivity in the desired fashion. Carbon 238-244 TBL1X/Y related 1 Homo sapiens 8-11 14746449-2 2004 The C13-C21 fragment was prepared from two simple starting materials that were joined in a catalytic alkyne-epoxide fragment coupling operation, whereas an intramolecular aldehyde-alkyne reductive coupling simultaneously formed the final carbon-carbon bond of the macrocycle and established the C13 carbinol configuration with complete selectivity in the desired fashion. Carbon 245-251 TBL1X/Y related 1 Homo sapiens 8-11 14623876-2 2004 This unusual N-C bond forming reaction is catalyzed by the thiamin diphosphate (ThP2)-dependent enzyme N2-(2-carboxyethyl)arginine synthase. Carbon 15-16 GLI family zinc finger 2 Homo sapiens 80-84 14733941-1 2004 The microenvironment of the probe coumarin 153 (C-153) in 1% bovine serum albumin (BSA) is more hydrophobic in nature compared to that in pure micelles or protein-surfactant complexes. Carbon 48-49 albumin Homo sapiens 68-81 14664854-6 2004 In addition, both pH level and organic carbon content are also known factors affecting the level of DDT and its metabolites. Carbon 39-45 D-dopachrome tautomerase Homo sapiens 100-103 14734217-12 2004 Post stress vitamin E treatment was found most effective than vitamins A and C in enhancing the levels of glutathione and activities of SOD, GST and catalase and decreasing lipid peroxidation. Carbon 77-78 catalase Rattus norvegicus 149-157 15258834-1 2004 Association studies were performed to confirm the effect of polymorphisms in apolipoprotein A1 ( ApoA1) on the high-density lipoprotein cholesterol (HDL-C) level and the incidence of myocardial infarction (MI). Carbon 153-154 apolipoprotein A1 Homo sapiens 77-94 14624355-7 2004 The acidic amino acids and their amides supported growth of the transconjugants only when supplied together with glucose, suggesting that the gltB-mutants had lost the ability to utilize amino acids as a carbon source. Carbon 204-210 glutamate synthase large subunit Pseudomonas putida KT2440 142-146 14747077-1 2004 The higher frequency peak near 1050 cm(-1) of the doublet in the infrared and Raman spectra of 2-thione-1,3-dithiole-4,5-dithiolate (DMIT) derivatives corresponds mainly to the stretching vibration of carbon-sulfur double bond in the terminal S=CS2 fragments of DMIT skeletons while the lower one corresponds mainly to the Fermi resonance peak between overtones of symmetric stretching vibration of two carbon-sulfur single bond in the S=CS2 fragment of DMIT skeletons and the higher frequency. Carbon 201-207 chorionic somatomammotropin hormone 2 Homo sapiens 245-248 14747077-1 2004 The higher frequency peak near 1050 cm(-1) of the doublet in the infrared and Raman spectra of 2-thione-1,3-dithiole-4,5-dithiolate (DMIT) derivatives corresponds mainly to the stretching vibration of carbon-sulfur double bond in the terminal S=CS2 fragments of DMIT skeletons while the lower one corresponds mainly to the Fermi resonance peak between overtones of symmetric stretching vibration of two carbon-sulfur single bond in the S=CS2 fragment of DMIT skeletons and the higher frequency. Carbon 201-207 chorionic somatomammotropin hormone 2 Homo sapiens 438-441 14747077-1 2004 The higher frequency peak near 1050 cm(-1) of the doublet in the infrared and Raman spectra of 2-thione-1,3-dithiole-4,5-dithiolate (DMIT) derivatives corresponds mainly to the stretching vibration of carbon-sulfur double bond in the terminal S=CS2 fragments of DMIT skeletons while the lower one corresponds mainly to the Fermi resonance peak between overtones of symmetric stretching vibration of two carbon-sulfur single bond in the S=CS2 fragment of DMIT skeletons and the higher frequency. Carbon 403-409 chorionic somatomammotropin hormone 2 Homo sapiens 245-248 14747077-1 2004 The higher frequency peak near 1050 cm(-1) of the doublet in the infrared and Raman spectra of 2-thione-1,3-dithiole-4,5-dithiolate (DMIT) derivatives corresponds mainly to the stretching vibration of carbon-sulfur double bond in the terminal S=CS2 fragments of DMIT skeletons while the lower one corresponds mainly to the Fermi resonance peak between overtones of symmetric stretching vibration of two carbon-sulfur single bond in the S=CS2 fragment of DMIT skeletons and the higher frequency. Carbon 403-409 chorionic somatomammotropin hormone 2 Homo sapiens 438-441 14747077-2 2004 On the other hand, the higher frequency near 500 cm(-1) corresponds mainly to the symmetric stretching vibration of two carbon-sulfur single bond in the S=CS2 fragments of DMIT skeletons while the lower one corresponds mainly to the symmetric stretching vibration of the four carbon-sulfur single bond in the S2C=CS2 fragments of DMIT skeletons. Carbon 120-126 chorionic somatomammotropin hormone 2 Homo sapiens 155-158 14747077-2 2004 On the other hand, the higher frequency near 500 cm(-1) corresponds mainly to the symmetric stretching vibration of two carbon-sulfur single bond in the S=CS2 fragments of DMIT skeletons while the lower one corresponds mainly to the symmetric stretching vibration of the four carbon-sulfur single bond in the S2C=CS2 fragments of DMIT skeletons. Carbon 120-126 chorionic somatomammotropin hormone 2 Homo sapiens 313-316 14747077-2 2004 On the other hand, the higher frequency near 500 cm(-1) corresponds mainly to the symmetric stretching vibration of two carbon-sulfur single bond in the S=CS2 fragments of DMIT skeletons while the lower one corresponds mainly to the symmetric stretching vibration of the four carbon-sulfur single bond in the S2C=CS2 fragments of DMIT skeletons. Carbon 276-282 chorionic somatomammotropin hormone 2 Homo sapiens 155-158 14747077-2 2004 On the other hand, the higher frequency near 500 cm(-1) corresponds mainly to the symmetric stretching vibration of two carbon-sulfur single bond in the S=CS2 fragments of DMIT skeletons while the lower one corresponds mainly to the symmetric stretching vibration of the four carbon-sulfur single bond in the S2C=CS2 fragments of DMIT skeletons. Carbon 276-282 chorionic somatomammotropin hormone 2 Homo sapiens 313-316 14709077-2 2004 A model C-(4a)-flavinhydroperoxide (FlHOOH) is described that contains the tricyclic isoalloxazine moiety, the C-4a-hydroperoxide functionality, and a beta-hydroxyethyl group to model the effect of the 2"-OH group of the ribityl side chain of native FADHOOH. Carbon 8-9 amyloid beta precursor protein Homo sapiens 149-155 15356734-0 2004 The profound influence of a single metal-carbon bond on the reactivity of bio-relevant cobalt(III) complexes. Carbon 41-47 mitochondrially encoded cytochrome c oxidase III Homo sapiens 94-97 15356734-6 2004 All in all the novel mechanistic information adds to the understanding of the profound effect that a single metal-carbon bond can have on the reactivity of such Co(III) complexes. Carbon 114-120 mitochondrially encoded cytochrome c oxidase III Homo sapiens 161-168 15366734-2 2004 Quite to the contrary, a mammalian enzyme, fructosamine 3-kinase, has recently been identified, which phosphorylates fructosamines on their third carbon, making them unstable and leading to their shedding from proteins. Carbon 146-152 fructosamine 3 kinase Homo sapiens 43-64 17265611-7 2004 The study showed that by the end of Ramadan fasting, there was a significant improvement in the mean levels of hemoglobin (Hb), TC, TG, HDL-c, LDL-c, TC/HDL, LDL/HDL, Lp (a), APA, APB, PT and systolic (SBP) and diastolic blood pressure (DBP) that persisted for four weeks after fasting (P < 0.05). Carbon 72-73 apolipoprotein B Homo sapiens 180-183 14688319-6 2004 Furthermore, NK cells respond to poly(I:C) by producing proinflammatory cytokines like IL-6 and IL-8, as well as the antiviral cytokine IFN-gamma. Carbon 40-41 interleukin 6 Homo sapiens 87-91 14688319-6 2004 Furthermore, NK cells respond to poly(I:C) by producing proinflammatory cytokines like IL-6 and IL-8, as well as the antiviral cytokine IFN-gamma. Carbon 40-41 C-X-C motif chemokine ligand 8 Homo sapiens 96-100 15258834-1 2004 Association studies were performed to confirm the effect of polymorphisms in apolipoprotein A1 ( ApoA1) on the high-density lipoprotein cholesterol (HDL-C) level and the incidence of myocardial infarction (MI). Carbon 153-154 apolipoprotein A1 Homo sapiens 97-102 14668444-3 2003 Primary and secondary kinetic isotope effects indicate that this ribozyme stabilizes a highly dissociative reaction with considerable sp2 hybridization and negligible bond order between the departing pyrophosphate leaving group and the anomeric carbon. Carbon 245-251 Sp2 transcription factor Homo sapiens 134-137 14705024-6 2004 Consistently, the distance from the electrophilic carbonyl carbon of (-)-EGCG to the hydroxyl group of Thr 1 was measured as 3.18 A. Carbon 50-56 thyroid hormone receptor beta Homo sapiens 103-108 14530281-1 2003 Rpb4, the fourth largest subunit of RNA polymerase II in Saccharomyces cerevisiae, is required for many phenotypes, including growth at high and low temperatures, sporulation, pseudohyphal growth, activated transcription of a subset of genes, and efficient carbon and energy metabolism. Carbon 257-263 DNA-directed RNA polymerase II subunit RPB4 Saccharomyces cerevisiae S288C 0-4 14641062-4 2003 Fructosamine 3-kinase phosphorylates with high affinity both low-molecular-mass and protein-bound fructosamines on the third carbon of their deoxyfructose moiety, leading to the formation of fructosamine 3-phosphates. Carbon 125-131 fructosamine 3 kinase Homo sapiens 0-21 14667785-8 2003 Examples including crambin, cytochrome c, cytochrome B and hemerythrin gave good secondary structure fits with overall alpha carbon atom rms deviations of between 5 and 5.6 A with an optimised hydrophobic term in the fitness function. Carbon 125-131 cytochrome c, somatic Homo sapiens 28-40 14642909-1 2003 Multiwall carbon nanotubes (MWCNTs) are filled in the cavity at the tip of a microelectrode to form a carbon nanotubes powder microelectrode (CNTs-PME). Carbon 10-16 cystatin B Homo sapiens 147-150 14622028-1 2003 The structural connections between the compounds of boron and carbon are extended using the mno rule beyond the borane-carbocation continuum, the lithium boride-polycarbyne analogy, and the magnesium boride (MgB(2))-graphite equivalence to beta-rhombohedral boron and fullerenes. Carbon 62-68 secretoglobin family 2A member 1 Homo sapiens 208-214 14562314-13 2003 The established achiral ketone TRHY precatalyst [Ru(Cl)(2)(ethP(2)(NH)(2))] (12) has turned out to be also a powerful precatalyst for the HY of 3 in iPrOH at s:c=10(6) and of some other substrates. Carbon 17-18 trichohyalin Homo sapiens 31-35 14710821-6 2003 Following the optimization of the paste composition, PPO-based carbon paste biosensors were prepared and presented excellent analytical properties toward catechol detection with a sensitivity of 4.7 A M(-1) cm(-2) and a response time lower than 20 s. The resulting biosensors were finally applied to the determination of epicatechin and ferulic acid as flavonol and polyphenol model, respectively. Carbon 63-69 protoporphyrinogen oxidase Homo sapiens 53-56 12890676-4 2003 We reported previously that PIS1 transcription is sensitive to carbon source. Carbon 63-69 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 28-32 14750991-4 2003 We observed significant reduction in charging of ice-embedded catalase crystals suspended over holes in a holey carbon film after coating them with a 30-A-thick layer of an amorphous alloy, Ti(88)Si(12). Carbon 112-118 catalase Homo sapiens 62-70 14500708-9 2003 Taken together, these results identify the inducible MAL activator as a client protein of the Hsp90 molecular chaperone complex and point to a critical role for chaperone function in alternate carbon source utilization in Saccharomyces cerevisiae. Carbon 193-199 Hsp90 family chaperone HSC82 Saccharomyces cerevisiae S288C 94-99 14656028-1 2003 One-carbon metabolism is under the influence of folate, vitamin B12 and genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR 677 C --> T and 1298 A --> C), of methionine synthase (MTR 2756 C --> G), methionine synthase reductase (MTRR 66 A --> G) and transcobalamin (TCN 776 C --> G). Carbon 4-10 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 223-252 14656028-1 2003 One-carbon metabolism is under the influence of folate, vitamin B12 and genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR 677 C --> T and 1298 A --> C), of methionine synthase (MTR 2756 C --> G), methionine synthase reductase (MTRR 66 A --> G) and transcobalamin (TCN 776 C --> G). Carbon 4-10 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Homo sapiens 254-258 14586087-2 2003 The nuclear anisotropic displacement parameters have been analysed showing that the carbon-oxygen skeleton conforms to a rigid-body (TLS) description. Carbon 84-90 FUS RNA binding protein Homo sapiens 133-136 14642909-1 2003 Multiwall carbon nanotubes (MWCNTs) are filled in the cavity at the tip of a microelectrode to form a carbon nanotubes powder microelectrode (CNTs-PME). Carbon 102-108 cystatin B Homo sapiens 147-150 12948639-4 2003 A defined deletion in the dapF gene led to a reduced growth of C. glutamicum in a medium with excess carbon but limited ammonium availability. Carbon 101-107 diaminopimelate epimerase Corynebacterium glutamicum ATCC 13032 26-30 12954072-0 2003 New bivalent PKC ligands linked by a carbon spacer: enhancement in binding affinity. Carbon 37-43 protein kinase C alpha Homo sapiens 13-16 12954072-3 2003 The dimers 2a-g of benzolactam showed a 200-fold increase in affinity to PKCalpha and -delta as the spacer length increased from 4 to 20 carbon atoms. Carbon 137-143 protein kinase C alpha Homo sapiens 73-92 14572101-4 2003 The solid product contains more than 80 wt % elemental carbon, has a surface area of about 65 m2/g, and is referred to as pyrolytic carbon black (CBp). Carbon 55-61 CREB binding protein Homo sapiens 146-149 14572101-5 2003 X-ray photoelectron spectroscopy (XPS) analysis has revealed that the CBp has mainly graphitic carbon structure similar to those of commercial carbon black. Carbon 95-101 CREB binding protein Homo sapiens 70-73 14572101-6 2003 The CBp may be used as semireinforcing carbon black in nontire rubber applications, or, after upgrading, as carbon black filler for tire. Carbon 39-45 CREB binding protein Homo sapiens 4-7 14572101-6 2003 The CBp may be used as semireinforcing carbon black in nontire rubber applications, or, after upgrading, as carbon black filler for tire. Carbon 108-114 CREB binding protein Homo sapiens 4-7 12940714-0 2003 Decarbonylative cross-coupling of cyclic anhydrides: introducing stereochemistry at an sp3 carbon in the cross-coupling event. Carbon 2-8 Sp3 transcription factor Homo sapiens 87-90 12953122-12 2003 However, the stimulation of AtNrt2.1 transcript accumulation by sucrose and glucose is abolished in an antisense AtHXK1 line, suggesting that HXK catalytic activity and carbon metabolism downstream of the HXK step are crucial for the sugar regulation of AtNrt2.1 expression. Carbon 169-175 nitrate transporter 2:1 Arabidopsis thaliana 28-36 12710887-8 2003 The detection of TeTx- and H(C)-TeTx-induced phosphorylation at Ser(9) of glycogen synthase kinase 3beta confirms Akt activation. Carbon 29-30 AKT serine/threonine kinase 1 Rattus norvegicus 114-117 12890704-4 2003 (3) The analogues bearing a second chlorophenoxy group on the asymmetric carbon atom showed a significant gCl-blocking activity. Carbon 73-79 germ cell-less 1, spermatogenesis associated Rattus norvegicus 106-109 12901650-0 2003 Organic and elemental carbon measurements during ACE-Asia suggest a longer atmospheric lifetime for elemental carbon. Carbon 22-28 angiotensin I converting enzyme Homo sapiens 49-52 12913167-2 2003 These studies suggested that the mtCA was involved in the inorganic carbon-concentrating mechanism. Carbon 68-74 CAH5 Chlamydomonas reinhardtii 33-37 12901650-0 2003 Organic and elemental carbon measurements during ACE-Asia suggest a longer atmospheric lifetime for elemental carbon. Carbon 110-116 angiotensin I converting enzyme Homo sapiens 49-52 12731856-3 2003 Strain IMB-1 grew slowly to high cell densities in the bioreactor using MeBr as its sole carbon and energy source. Carbon 89-95 karyopherin subunit beta 1 Homo sapiens 7-12 12839436-2 2003 Generation of highly acidic sp3 carbons in pyrroles and indoles. Carbon 32-39 Sp3 transcription factor Homo sapiens 28-31 12788342-2 2003 Changes to the bicyclic core, removing either the terminal amino substituent or the sulfonyl group from the side chain, and altering either the carbon skeleton or stereochemistry of the isoleucine residue, decreases the potency of inhibition of isoleucyl tRNA synthetase. Carbon 144-150 isoleucyl-tRNA synthetase 1 Homo sapiens 245-270 12894833-1 2003 The electrochemical behavior of cytochrome c (cyt c) and its interaction with DNA at a Co/glassy carbon (GC) ion implantation modified electrode were studied by linear sweep and cyclic voltammetry. Carbon 97-103 cytochrome c, somatic Homo sapiens 32-44 12894833-1 2003 The electrochemical behavior of cytochrome c (cyt c) and its interaction with DNA at a Co/glassy carbon (GC) ion implantation modified electrode were studied by linear sweep and cyclic voltammetry. Carbon 97-103 cytochrome c, somatic Homo sapiens 46-51 12927115-4 2003 T, E(LUMO) (the energy of the lowest unoccupied molecular orbital), molecular size or average molecular polarizability (alpha), and the net atomic charges on chlorine, hydrogen and carbon atoms of PCB molecules, are major factors governing logK(OA). Carbon 181-187 pyruvate carboxylase Homo sapiens 197-200 14509706-6 2003 Column studies using a 3H2O tracer and vitamin B12 in distilled water (10 microM) resulted in a B12 retardation factor (R) of approximately 2 for both sand (0.14% organic carbon) and a sandy soil (2.5% organic carbon). Carbon 171-177 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 47-50 14509706-6 2003 Column studies using a 3H2O tracer and vitamin B12 in distilled water (10 microM) resulted in a B12 retardation factor (R) of approximately 2 for both sand (0.14% organic carbon) and a sandy soil (2.5% organic carbon). Carbon 210-216 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 47-50 12769550-7 2003 Proton-mediated 2D exchange spectra of fibrils formed by residues 16-22 of the 40-residue Alzheimer"s beta-amyloid peptide show strong nonsequential, intermolecular cross-peaks between alpha-carbons that dictate an antiparallel beta-sheet structure in which residue 16+k aligns with residue 22-k. Carbon 191-198 amyloid beta precursor protein Homo sapiens 102-122 12805577-4 2003 Boolean logic was used to model the effect of these carbon/light interactions on three target genes involved in nitrogen assimilation: asparagine synthetase (ASN1 and ASN2) and glutamine synthetase (GLN2). Carbon 52-58 glutamate-ammonia ligase Homo sapiens 177-197 12738881-0 2003 The putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of carbon and nitrogen metabolism in Arabidopsis thaliana. Carbon 75-81 glutamate receptor 1.1 Arabidopsis thaliana 13-35 12738881-0 2003 The putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of carbon and nitrogen metabolism in Arabidopsis thaliana. Carbon 75-81 glutamate receptor 1.1 Arabidopsis thaliana 37-45 12738881-3 2003 We used an antisense strategy to demonstrate that the putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of C and N metabolism in Arabidopsis. Carbon 125-126 glutamate receptor 1.1 Arabidopsis thaliana 63-85 12738881-3 2003 We used an antisense strategy to demonstrate that the putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of C and N metabolism in Arabidopsis. Carbon 125-126 glutamate receptor 1.1 Arabidopsis thaliana 87-95 12894502-6 2003 For LPC-10 cells treated with C-36 IL-6 and TNF-alpha levels also increase. Carbon 6-7 tumor necrosis factor Homo sapiens 44-53 12713571-4 2003 Enzymatic analysis using CHO cells overexpressing human Delta-6 desaturase/FADS2 indicates catalysis of a "polyunsaturated fatty acid type" reaction, but also an unexpected "sebaceous-type" reaction, that of converting palmitate into the mono-unsaturated fatty acid sapienate, a 16-carbon fatty acid with a single cis double bond at the sixth carbon from the carboxyl end. Carbon 282-288 fatty acid desaturase 2 Homo sapiens 56-74 12713571-4 2003 Enzymatic analysis using CHO cells overexpressing human Delta-6 desaturase/FADS2 indicates catalysis of a "polyunsaturated fatty acid type" reaction, but also an unexpected "sebaceous-type" reaction, that of converting palmitate into the mono-unsaturated fatty acid sapienate, a 16-carbon fatty acid with a single cis double bond at the sixth carbon from the carboxyl end. Carbon 282-288 fatty acid desaturase 2 Homo sapiens 75-80 12699390-4 2003 2,4-Diamino-5-[5"-(4-carboxy-1-butynyl)-2"-methoxybenzyl]pyrimidine (2), with one less carbon than 3 in the side chain, had a selectivity index of 910 against Ma DHFR and was 43 times more potent than TMP. Carbon 87-93 dihydrofolate reductase Rattus norvegicus 162-166 12746135-4 2003 Recently, a highly sensitive biosensor was developed for NTE activity using a tyrosinase carbon-paste electrode for amperometric detection of phenol produced by hydrolysis of the substrate, phenyl valerate. Carbon 89-95 patatin like phospholipase domain containing 6 Homo sapiens 57-60 12547836-7 2003 Alignment of the protein structures of the ligand-binding domains of ERalpha and ERbeta revealed one mismatched residue, Leu-384 in ERalpha and Met-283 in ERbeta, which may be responsible for making contact with the methyl substituent at the chiral carbon of IA-S and IA-R. Mutagenesis and exchange of this one residue showed that the binding of IA-R and IA-S was not affected by this mutation in ERalpha and ERbeta. Carbon 249-255 estrogen receptor 1 Homo sapiens 69-76 12739670-1 2003 Carbon hollow spheres (400-600 nm) and vessels (400 nm x 3000 nm) have been synthesized from sp3-CCl4 at 190 and 230 degrees C, respectively. Carbon 0-6 Sp3 transcription factor Homo sapiens 93-96 12547836-7 2003 Alignment of the protein structures of the ligand-binding domains of ERalpha and ERbeta revealed one mismatched residue, Leu-384 in ERalpha and Met-283 in ERbeta, which may be responsible for making contact with the methyl substituent at the chiral carbon of IA-S and IA-R. Mutagenesis and exchange of this one residue showed that the binding of IA-R and IA-S was not affected by this mutation in ERalpha and ERbeta. Carbon 249-255 estrogen receptor 1 Homo sapiens 132-139 12547836-7 2003 Alignment of the protein structures of the ligand-binding domains of ERalpha and ERbeta revealed one mismatched residue, Leu-384 in ERalpha and Met-283 in ERbeta, which may be responsible for making contact with the methyl substituent at the chiral carbon of IA-S and IA-R. Mutagenesis and exchange of this one residue showed that the binding of IA-R and IA-S was not affected by this mutation in ERalpha and ERbeta. Carbon 249-255 estrogen receptor 1 Homo sapiens 132-139 12671535-8 2003 In addition, cells treated with the C-36 for 48 hours increased in NFkappaB (nuclear factor kappa B) activity. Carbon 36-37 nuclear factor kappa B subunit 1 Homo sapiens 67-75 12676688-6 2003 Overexpression of GLY1 enabled a Pdc(-) strain to grow under conditions of carbon limitation in chemostat cultures on glucose as the sole carbon source, indicating that acetaldehyde formed by threonine aldolase served as a precursor for the synthesis of cytosolic acetyl-CoA. Carbon 75-81 threonine aldolase GLY1 Saccharomyces cerevisiae S288C 18-22 12676688-6 2003 Overexpression of GLY1 enabled a Pdc(-) strain to grow under conditions of carbon limitation in chemostat cultures on glucose as the sole carbon source, indicating that acetaldehyde formed by threonine aldolase served as a precursor for the synthesis of cytosolic acetyl-CoA. Carbon 138-144 threonine aldolase GLY1 Saccharomyces cerevisiae S288C 18-22 12671535-8 2003 In addition, cells treated with the C-36 for 48 hours increased in NFkappaB (nuclear factor kappa B) activity. Carbon 36-37 nuclear factor kappa B subunit 1 Homo sapiens 77-99 12623637-0 2003 p53-dependent hyperthermic enhancement of tumour growth inhibition by X-ray or carbon-ion beam irradiation. Carbon 79-85 tumor protein p53 Homo sapiens 0-3 12702688-5 2003 During the isolation of mutants, two new classes of flavonoid mutants (tt18, tt19) were isolated from carbon-ion-mutagenized M2 plants. Carbon 102-108 leucoanthocyanidin dioxygenase Arabidopsis thaliana 71-75 12702688-5 2003 During the isolation of mutants, two new classes of flavonoid mutants (tt18, tt19) were isolated from carbon-ion-mutagenized M2 plants. Carbon 102-108 glutathione S-transferase phi 12 Arabidopsis thaliana 77-81 12496283-5 2003 GPR41 is related to GPR43 (52% similarity; 43% identity) and was activated by similar ligands but with differing specificity for carbon chain length, with pentanoate being the most potent agonist. Carbon 129-135 free fatty acid receptor 3 Homo sapiens 0-5 12633748-9 2003 Following sonolysis in the presence of ATX-C(x), a strong correlation for the yield of carbon-centered radicals and cell killing was observed. Carbon 87-93 ectonucleotide pyrophosphatase/phosphodiesterase 2 Homo sapiens 39-42 12456389-4 2003 Cultured macrophages (RAW 264.7 cells) exposed continuously to a well-defined model of particulate matter (benzo[a]pyrene adsorbed onto carbon black) induced HO-1 gene expression in a time-dependent manner. Carbon 136-142 heme oxygenase 1 Mus musculus 158-162 12666931-0 2003 ACE-Asia intercomparison of a thermal-optical method for the determination of particle-phase organic and elemental carbon. Carbon 115-121 angiotensin I converting enzyme Homo sapiens 0-3 12662090-3 2003 During the course of these transformations, the C-10 carbon of the botryane skeleton was found to exhibit an interesting high regioselectivity to oxidizing and reducing agents. Carbon 53-59 homeobox C10 Homo sapiens 48-52 12507833-4 2003 A marked increase in the propensity of FA-modified CG 117-136 to form an alpha-helix structure was observed for the C-8, C-10 and C-12 derivatives compared with unmodified/short-chain and long-chain (C-14, C-16, C-18) derivatives. Carbon 51-52 Bardet-Biedl syndrome 9 Homo sapiens 212-216 12792994-0 2003 [Study on the unscheduled DNA synthesis in primary rat hepatocyte induced by source water, tap water and active carbon-treated tap water]. Carbon 112-118 nuclear RNA export factor 1 Rattus norvegicus 127-130 12792994-1 2003 To study the mutagenicity of source water with different turbidities, tap water and active carbon-treated tap water, unscheduled DNA synthesis in primary rat hepatocyte was detected. Carbon 91-97 nuclear RNA export factor 1 Rattus norvegicus 106-109 12792994-2 2003 Increased unscheduled DNA synthesis was found in a dose-depend manner inducted by tap water, source water and tap water treated with 5, 10 and 15 milligrammes active carbon per liter water. Carbon 166-172 nuclear RNA export factor 1 Rattus norvegicus 82-85 12792994-2 2003 Increased unscheduled DNA synthesis was found in a dose-depend manner inducted by tap water, source water and tap water treated with 5, 10 and 15 milligrammes active carbon per liter water. Carbon 166-172 nuclear RNA export factor 1 Rattus norvegicus 110-113 12792994-5 2003 It is suggested that the development of the water treatment technics including sedimentation, filtration and treatment with active carbon is needed for decreasing or eliminating the mutagenicity of tap water. Carbon 131-137 nuclear RNA export factor 1 Rattus norvegicus 198-201 12547783-4 2003 For phosphatidylcholine spin-labeled at different positions down the sn-2 chain, the amplitude of the deuterium signal decreases toward the center of the membrane, and is reduced to zero from the C-12 atom position onward. Carbon 196-197 solute carrier family 38 member 5 Homo sapiens 69-73 12586704-8 2003 ELO-2 cooperates with the previously reported ELO-1 in 20-carbon PUFA production, and at least one of the enzymes must function to provide normal growth and development in C. elegans. Carbon 58-64 Elongation of long chain fatty acids protein 1 Caenorhabditis elegans 46-51 12446735-7 2003 This binding pocket is distinct from that of the biogenic amine receptors and rhodopsin where the native ligands (also composed of a carbon ring and a carbon chain) are accommodated in an opposing direction. Carbon 133-139 rhodopsin Homo sapiens 78-87 12446735-7 2003 This binding pocket is distinct from that of the biogenic amine receptors and rhodopsin where the native ligands (also composed of a carbon ring and a carbon chain) are accommodated in an opposing direction. Carbon 151-157 rhodopsin Homo sapiens 78-87 12698540-8 2003 In PTH levels (pmol/l) the group C differed significantly from groups A and B (A: 27.4 +/- 32.0, B: 23.7 +/- 16.5, C: 6.2 +/- 2.4, C vs. A, p < 0.01, C vs. B, p < 0.001, RM: 1.0-6.8). Carbon 33-34 parathyroid hormone Homo sapiens 3-6 12582119-0 2003 Yap1 accumulates in the nucleus in response to carbon stress in Saccharomyces cerevisiae. Carbon 47-53 DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C 0-4 12582119-4 2003 We show that the localization of Yap1 is similarly sensitive to carbon stress. Carbon 64-70 DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C 33-37 12582119-5 2003 When glucose-grown cells were shifted to medium containing glycerol or no added carbon source, green fluorescent protein (GFP)-Yap1 accumulated in the nucleus. Carbon 80-86 DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C 127-131 12582119-8 2003 Addition of glutathione to the medium inhibited nuclear accumulation of GFP-Yap1 in response to carbon stress but did not affect the relocalization of Gal83 or Mig1. Carbon 96-102 DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C 76-80 12582119-10 2003 These findings suggest a role for Yap1 in the response to carbon stress. Carbon 58-64 DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C 34-38 12429747-8 2003 The general defect in the absence of Rpb4 is in the expression of metabolic genes, especially those involved in carbon metabolism and energy generation. Carbon 112-118 DNA-directed RNA polymerase II subunit RPB4 Saccharomyces cerevisiae S288C 37-41 12524286-12 2003 Infrared results also indicated that interactions involving SP-B/C and lipids led to exclusion of PC and PG lipids from the compressed interfacial monolayer, in agreement with our previous report on the phase morphology of lipid monolayers containing 1 wt % SP-B/C. Carbon 65-66 surfactant protein B Bos taurus 60-64 12524286-12 2003 Infrared results also indicated that interactions involving SP-B/C and lipids led to exclusion of PC and PG lipids from the compressed interfacial monolayer, in agreement with our previous report on the phase morphology of lipid monolayers containing 1 wt % SP-B/C. Carbon 65-66 surfactant protein B Bos taurus 258-262 12690917-0 2003 Effects of carbon-coated coronary stents on the markers of inflammation, thrombin generation and platelet and endothelial activation. Carbon 11-17 coagulation factor II, thrombin Homo sapiens 73-81 12507833-4 2003 A marked increase in the propensity of FA-modified CG 117-136 to form an alpha-helix structure was observed for the C-8, C-10 and C-12 derivatives compared with unmodified/short-chain and long-chain (C-14, C-16, C-18) derivatives. Carbon 116-117 Bardet-Biedl syndrome 9 Homo sapiens 212-216 12507833-4 2003 A marked increase in the propensity of FA-modified CG 117-136 to form an alpha-helix structure was observed for the C-8, C-10 and C-12 derivatives compared with unmodified/short-chain and long-chain (C-14, C-16, C-18) derivatives. Carbon 116-117 Bardet-Biedl syndrome 9 Homo sapiens 212-216 15841223-3 2003 Previous ecdysteroid QSAR and molecular modelling studies predicted that the cavity of the ligand binding domain of the ecdysteroid receptor would possess space in the vicinity of C-11/C-12 of the ecdysteroid. Carbon 180-181 Ecdysone receptor Drosophila melanogaster 120-140 15841223-3 2003 Previous ecdysteroid QSAR and molecular modelling studies predicted that the cavity of the ligand binding domain of the ecdysteroid receptor would possess space in the vicinity of C-11/C-12 of the ecdysteroid. Carbon 185-186 Ecdysone receptor Drosophila melanogaster 120-140 12176975-6 2002 However, recycling of glucose carbon from lactate back to glucose was lower in the PPARalpha null than in WT (39% versus 51%, p < 0.02). Carbon 30-36 peroxisome proliferator activated receptor alpha Mus musculus 83-92 12513160-5 2002 The stability of the sp2-sp network has important implications for astrophysics and for the production of novel carbon-based systems. Carbon 112-118 Sp2 transcription factor Homo sapiens 21-24 12443781-2 2002 The results support the hypothesis for a subsite within CB1 and CB2 binding domain at the level of the benzylic side chain carbon in the tetrahydrocannabinol and cannabidiol series. Carbon 123-129 cannabinoid receptor 1 Homo sapiens 56-59 12793767-6 2002 Preliminary data are presented that ascorbate also alters the spectrum of CD59- mutations induced by the carbon beam, mainly by reducing the incidence of small mutations and mutants displaying transmissible genomic instability (TGI), while large mutations are unaffected. Carbon 105-111 CD59 molecule (CD59 blood group) Homo sapiens 74-78 12220618-10 2002 To examine which mitogen-activated protein kinases (MAPKs) are involved in C(2)-induced contraction, specific MAPK inhibitors (MEK inhibitor, PD98059, and p38 MAPK inhibitor, SB202190) are used. Carbon 75-76 mitogen-activated protein kinase 1 Homo sapiens 52-56 12561343-1 2002 In this paper, the adsorption of human serum albumin(HSA), human serum fibrinogen (HFG) and human serum immunoglobin(IgG) on diamond like carbon film(DLC) has been studied in comparison with diamond film (DF) and graphite. Carbon 138-144 fibrinogen beta chain Homo sapiens 71-81 12434176-0 2002 Cranioplasty with individual carbon fibre reinforced polymere (CFRP) medical grade implants based on CAD/CAM technique. Carbon 29-35 calmodulin 3 Homo sapiens 105-108 12244097-6 2002 Several mutants were identified that have a defect in growth when switched from a fermentable to a nonfermentable carbon source that is corrected by the expression of Bcl-x(L). Carbon 114-120 BCL2 like 1 Homo sapiens 167-175 12223476-5 2002 We discovered that C-36 is a powerful and specific transcriptional down-regulator of bile acid synthesis in primary rat hepatocytes, through inhibition of the cholesterol 7alpha-hydroxylase/CYP7A1 (7alpha-hydroxylase) promoter. Carbon 19-20 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 159-189 12223476-5 2002 We discovered that C-36 is a powerful and specific transcriptional down-regulator of bile acid synthesis in primary rat hepatocytes, through inhibition of the cholesterol 7alpha-hydroxylase/CYP7A1 (7alpha-hydroxylase) promoter. Carbon 19-20 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 190-196 12454062-1 2002 In the yeast Saccharomyces cerevisiae, certain mutant alleles of YME4, YME6, and MDM10 cause an increased rate of mitochondrial DNA migration to the nucleus, carbon-source-dependent alterations in mitochondrial morphology, and increased rates of mitochondrial DNA loss. Carbon 158-164 Mdm10p Saccharomyces cerevisiae S288C 81-86 12379779-10 2002 Do reversible shifts of C(3)/CAM-intermediate plants between the C(3)-CAM-C(3) modes of photosynthesis indicate that C(3)-photosynthesis provides better protection from irradiance stress? Carbon 24-25 calmodulin 3 Homo sapiens 70-73 12391014-5 2002 Human neutrophils transformed COX-2-ASA-derived 17R-hydroxy-DHA into two sets of novel di- and trihydroxy products; one initiated via oxygenation at carbon 7 and the other at carbon 4. Carbon 149-155 mitochondrially encoded cytochrome c oxidase II Homo sapiens 30-35 12391014-5 2002 Human neutrophils transformed COX-2-ASA-derived 17R-hydroxy-DHA into two sets of novel di- and trihydroxy products; one initiated via oxygenation at carbon 7 and the other at carbon 4. Carbon 175-181 mitochondrially encoded cytochrome c oxidase II Homo sapiens 30-35 12375998-2 2002 The reaction of N-pyridylindolines with CO and ethylene in the presence of Ru3(CO)12 results in direct carbonylation at a C-H bond delta to the pyridine sp2 nitrogen, which represents a new type of C-H/CO/olefin coupling. Carbon 40-41 Sp2 transcription factor Homo sapiens 153-156 12397986-0 2002 First anionic silyl migration from sp2 carbon to carbonyl oxygen. Carbon 39-45 Sp2 transcription factor Homo sapiens 35-38 12393187-2 2002 In Saccharomyces cerevisiae, expression of the COQ5 gene, encoding for a C-methyltransferase involved in CoQ synthesis, is transcriptionally regulated by carbon source. Carbon 154-160 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase Saccharomyces cerevisiae S288C 47-51 12393187-6 2002 These results suggest that the regulation of COQ5 gene expression by carbon source is multifactorial and involves the interaction of various transcription factors. Carbon 69-75 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase Saccharomyces cerevisiae S288C 45-49 12355524-12 2002 The cyclic SAA containing oligomer cyclo [f-SAA1-beta-hGly](3) (5) exhibits a C(3) symmetric conformation on the NMR chemical shift time scale. Carbon 78-79 serum amyloid A1 Homo sapiens 44-48 12397986-2 2002 1,4-Silyl migration from sp2 carbon to carbonyl oxygen proceeded by the treatment of (Z)-beta-trimethylsilyl-alpha,beta-unsaturated ketones with copper(I) tert-alkoxide to afford vinylmetal species, which reacted with allylic halides to produce enol trimethylsilyl ethers of beta-alk-2-enyl-alpha,beta-unsaturated ketones with complete retention of configuration. Carbon 29-35 Sp2 transcription factor Homo sapiens 25-28 12234495-2 2002 In these studies, the ODC1 gene was identified as able, in low-copy, to rescue a yeast strain that is unable to grow on oleic acid but can grow on other nonfermentable carbon sources. Carbon 168-174 mitochondrial 2-oxodicarboxylate carrier Saccharomyces cerevisiae S288C 22-26 12355162-1 2002 The aim of this work was to examine the role of cytosolic phosphoglucomutase (cPGM; EC 5.4.2.2) in photosynthetic carbon partitioning. Carbon 114-120 phosphoglucomutase, cytoplasmic Solanum tuberosum 48-76 12270821-1 2002 Pseudomonas aeruginosa PAO1 utilizes proline as the sole source of carbon and nitrogen via a bifunctional enzyme (the putA gene product) that has both proline dehydrogenase (EC 1.5.99.8) and pyrroline 5-carboxylate dehydrogenase (EC 1.5.1.12) activities. Carbon 67-73 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase Pseudomonas aeruginosa PAO1 118-122 12236755-10 2002 At catalytic conditions, the calculated free energies of C-H addition are 31.3 and 33.7 kcal/mol for CyH and n-PrH addition, respectively. Carbon 57-58 chymase 1 Homo sapiens 101-104 12124773-7 2002 On the other hand, for maximal release of bFGF from ECM, the position of the carboxylic group should be three carbons away from the phenol ring. Carbon 110-117 fibroblast growth factor 2 Homo sapiens 42-46 12375854-8 2002 To demonstrate the technique, the internal surface of a beverage can, contaminated with a 40 microm diameter carbonised oven impurity, consisting mainly of sp2- and sp3-hybridised saturated carbon bonds, has been used as a case study. Carbon 109-115 Sp2 transcription factor Homo sapiens 156-159 12226529-2 2002 Arabidopsis CYP90B1/DWF4 and CYP90A1/CPD are responsible for respective C-22 and C-23 hydroxylation of the steroid side chain and CYP85A1 catalyzes C-6 oxidation of 6-deoxo intermediates, whereas the functions of CYP90C1/ROT3, CYP90D1, and CYP85A2 are still unknown. Carbon 12-13 Cytochrome P450 superfamily protein Arabidopsis thaliana 29-36 12204291-2 2002 Differential normal pulse voltammetry with carbon fiber electrodes identified distinct oxidation currents at +120 mV (peak 1: catechol signals) and +280 mV (peak 2: 5-hydroxyindole signals). Carbon 43-49 pseudopodium-enriched atypical kinase 1 Rattus norvegicus 118-124 12244446-0 2002 Carbon assimilation and metabolism in potato leaves deficient in plastidial phosphoglucomutase. Carbon 0-6 phosphoglucomutase Solanum tuberosum 76-94 12226510-5 2002 Concomitant with the enhanced SMT1 activity was an increase in endogenous 3-hydroxy-3-methylglutaryl coenzyme A reductase activity, from which one can speculate that reduced levels of cycloartenol feed back to up-regulate 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and thereby control the carbon flux into sterol biosynthesis. Carbon 303-309 3-hydroxy-3-methylglutaryl-coenzyme A reductase Nicotiana tabacum 74-121 12244446-4 2002 The aim of the current work was to examine the role of plastidial phosphoglucomutase (pPGM, EC 5.4.2.2) in photosynthetic carbon partitioning. Carbon 122-128 phosphoglucomutase Solanum tuberosum 66-84 12127539-6 2002 Low but significant phosphorylation rates in the range of 0.18% that of thymidine were observed for the carbon-linked 3"-carboranyl thymidine analogues in phosphoryl transfer assays using recombinant preparations of thymidine kinases 1 (TK1) and thymidine kinases 2 (TK2). Carbon 104-110 thymidine kinase 1 Homo sapiens 237-240 12184773-4 2002 The saturation of one azomethine group causes the products to assume a fac configuration and induces the formation of one asymmetric carbon and one asymmetric nitrogen center in the chelating system. Carbon 133-139 FA complementation group C Homo sapiens 71-74 12166938-1 2002 Endocannabinoid stucture-activity relationships (SAR) indicate that the CB1 receptor recognizes ethanolamides whose fatty acid acyl chains have 20 or 22 carbons, with at least three homoallylic double bonds and saturation in at least the last five carbons of the acyl chain. Carbon 153-160 cannabinoid receptor 1 Homo sapiens 72-75 12166938-1 2002 Endocannabinoid stucture-activity relationships (SAR) indicate that the CB1 receptor recognizes ethanolamides whose fatty acid acyl chains have 20 or 22 carbons, with at least three homoallylic double bonds and saturation in at least the last five carbons of the acyl chain. Carbon 248-255 cannabinoid receptor 1 Homo sapiens 72-75 12146632-6 2002 Increasing Q(Cl)+, (the most positive net atomic charges on a chlorine atom) and Q(C)- (the largest negative net atomic charge on a carbon atom) values of PCBs results in decreasing lg K(OA) values, implying possible intermolecular electrostatic interactions between octanol and PCB molecules. Carbon 132-138 pyruvate carboxylase Homo sapiens 155-158 12148096-5 2002 The effect of apo E2 triglyceride (TG)-rich lipoproteins, including remnant lipoproteins, on the accumulation of cholesteryl esters by human mesangial cells (HMCs) was estimated by measuring the stimulation of radioactive carbon-labeled oleate incorporation into cholesteryl esters. Carbon 222-228 apolipoprotein E Homo sapiens 14-20 11975663-1 2002 Fructosamine 3-kinase, which phosphorylates low-molecular-mass and protein-bound fructosamines on the third carbon of their deoxyfructose moiety, is quite active in erythrocytes, and was proposed to initiate a process removing fructosamine residues from proteins. Carbon 108-114 fructosamine 3 kinase Homo sapiens 0-21 12139626-9 2002 Two-hybrid analysis showed that Tot4p also interacts with Cdc19p, suggesting that Tot4p plays an additional role in concert with Cdc19p, perhaps co-ordinating cell growth with carbon source metabolism. Carbon 176-182 pyruvate kinase CDC19 Saccharomyces cerevisiae S288C 58-64 12211632-16 2002 TNF-alpha production was diminished in the groups treated with quartz, carbon black, and coal dust alone whereas in the quartz/PVNO- and amorphous SiO2-treated groups an elevated TNF-alpha production was seen. Carbon 71-77 tumor necrosis factor Rattus norvegicus 0-9 12130688-4 2002 Our recent investigations with electrophilic prostaglandins enabled us to devise a pharmacophore and mechanism of action hypothesis relevant to this problem: a cross-conjugated alpha,beta-unsaturated dienone with two sterically accessible electrophilic beta-carbons is a molecular determinant that confers activity among this class of ubiquitin isopeptidases inhibitors, and that inhibitors of ubiquitin isopeptidases cause cell death in vitro independently of p53. Carbon 258-265 tumor protein p53 Homo sapiens 461-464 12139626-9 2002 Two-hybrid analysis showed that Tot4p also interacts with Cdc19p, suggesting that Tot4p plays an additional role in concert with Cdc19p, perhaps co-ordinating cell growth with carbon source metabolism. Carbon 176-182 pyruvate kinase CDC19 Saccharomyces cerevisiae S288C 129-135 12230195-4 2002 This membrane technology supported excellent NO3- and nitrite (NO2-) removal once H2 and carbon limitations were corrected. Carbon 89-95 NBL1, DAN family BMP antagonist Homo sapiens 45-48 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 129-135 homeobox C10 Homo sapiens 122-127 12203349-5 2002 The macrocycle 32 is particularly interesting in that it contains 60 carbon atoms in the inner ring, and indeed a decomposition mode consecutively cleaving off ethylene units from it as well as from 31 and tetramethylethylene from the permethylated exp-[6]rotane 30 has been proved by differential scanning calorimetry with evolved gas analysis. Carbon 69-75 exportin 6 Homo sapiens 249-255 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 115-116 homeobox C10 Homo sapiens 122-127 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 115-116 homeobox C10 Homo sapiens 185-190 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 115-116 homeobox C10 Homo sapiens 185-190 12084061-5 2002 These findings suggest that the difference in adduct agonist activity reflects the differences in the positive charge and carbon chain length of the polyamine covalently linked with the VIP Gln16 residue. Carbon 122-128 vasoactive intestinal polypeptide Mus musculus 186-189 12182322-6 2002 Results indicate that p53 is involved in the response of TK6 cells to fast neutrons and carbon ions, as measured by cell proliferation and occurrence of apoptosis. Carbon 88-94 tumor protein p53 Homo sapiens 22-25 11959468-0 2002 Ion-exchange voltammetry and electrocatalytic sensing capabilities of cytochrome c at polyestersulfonated ionomer coated glassy carbon electrodes. Carbon 128-134 cytochrome c, somatic Homo sapiens 70-82 11927575-4 2002 Moreover, phosphorylation of p53 Ser-15 induced by C-1027 was independent of ATM, ATR, or DNA-PK function. Carbon 51-52 tumor protein p53 Homo sapiens 29-32 11927575-4 2002 Moreover, phosphorylation of p53 Ser-15 induced by C-1027 was independent of ATM, ATR, or DNA-PK function. Carbon 51-52 ATR serine/threonine kinase Homo sapiens 82-85 12039737-1 2002 Inactivation of TPI1, the Saccharomyces cerevisiae structural gene encoding triose phosphate isomerase, completely eliminates growth on glucose as the sole carbon source. Carbon 156-162 triose-phosphate isomerase TPI1 Saccharomyces cerevisiae S288C 16-20 12123456-10 2002 FLO11-independent cell-cell attachment, cell wall integrity, and/or polarized growth are affected by carbon source metabolism. Carbon 101-107 Flo11p Saccharomyces cerevisiae S288C 0-5 12071745-12 2002 These data, including comparisons with inhibition data from carbon analogues, are consistent with binding of the silanediols by chelation of the ACE active site zinc, whereas the methylsilanols ligate poorly. Carbon 60-66 angiotensin I converting enzyme Homo sapiens 145-148 12051672-3 2002 Recent work suggested that the accumulation of lipids in developing Arabidopsis seeds was more closely correlated with the expression of pyruvate dehydrogenase complex than with the expression of ACS, suggesting that most of the carbon for fatty acid formation in the plastids of seeds comes from pyruvate rather than from acetate. Carbon 229-235 acetyl-CoA synthetase Arabidopsis thaliana 196-199 11907033-8 2002 Distinct from the Na(+)-independent cystine/glutamate transporter xCT structurally related to AGT1, AGT1 did not accept cystine, homocysteate, and l-alpha-aminoadipate and exhibited high affinity to aspartate as well as glutamate, suggesting that the negative charge recognition site in the side chain-binding site of AGT1 would be closer to the alpha-carbon binding site compared with that of xCT. Carbon 352-358 solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 Mus musculus 100-104 11907033-8 2002 Distinct from the Na(+)-independent cystine/glutamate transporter xCT structurally related to AGT1, AGT1 did not accept cystine, homocysteate, and l-alpha-aminoadipate and exhibited high affinity to aspartate as well as glutamate, suggesting that the negative charge recognition site in the side chain-binding site of AGT1 would be closer to the alpha-carbon binding site compared with that of xCT. Carbon 352-358 solute carrier family 7, (cationic amino acid transporter, y+ system) member 13 Mus musculus 100-104 19750618-0 2002 Sp carbon chains surrounded by sp3 carbon double helices: a class of molecules that are accessible by self-assembly and models for "insulated" molecular-scale devices. Carbon 35-41 Sp3 transcription factor Homo sapiens 31-34 11959468-1 2002 The incorporation and electrochemical behaviour of cytochrome c (Cyt C) at glassy carbon electrodes modified with the polyestersulfonated ionomer Eastman AQ 55 are examined. Carbon 82-88 cytochrome c, somatic Homo sapiens 65-70 12027183-1 2002 This paper presents results of measurements of short (0.3 ps, 0.2 ns, and 10 ns) laser pulse transmissions through a liquid suspension of fine carbon particles (named CBS for "carbon-black suspension") at input-pulse energies up to 10 mJ. Carbon 143-149 cystathionine beta-synthase Homo sapiens 167-170 18968649-0 2002 Development of a disposable immunosensor for the detection of human heart fatty-acid binding protein in human whole blood using screen-printed carbon electrodes. Carbon 143-149 fatty acid binding protein 3 Homo sapiens 68-100 12027183-1 2002 This paper presents results of measurements of short (0.3 ps, 0.2 ns, and 10 ns) laser pulse transmissions through a liquid suspension of fine carbon particles (named CBS for "carbon-black suspension") at input-pulse energies up to 10 mJ. Carbon 176-182 cystathionine beta-synthase Homo sapiens 167-170 11888729-2 2002 Screen-printed carbon electrodes (SPCEs) were tailored with the enzyme sulfite oxidase and cytochrome c and the response is generated through the resulting enzymatic and electrocatalytic reactions involving SO(3)(2-), formed when SO(2) gas is dissolved in the supporting electrolyte. Carbon 15-21 cytochrome c, somatic Homo sapiens 91-103 11941464-8 2002 IDH protein was also increased in the transformed plants with low Fd-GOGAT, suggesting that both IDH and ICDH are involved in the production of carbon skeletons (and ultimately alpha-ketoglutarate) necessary for the re-assimilation of NH4+. Carbon 144-150 isocitrate dehydrogenase [NADP] Nicotiana tabacum 0-3 12073030-7 2002 Northern analysis revealed that the level of MVD expression is affected by (1) the carbon source in the growth medium, (2) the growth phase, and (3) the growth form of the fungus (yeast-like or hyphal). Carbon 83-89 mevalonate diphosphate decarboxylase Homo sapiens 45-48 11969406-2 2002 Two sets of (1)H-(13)C resonances were found in a titration series of NMR spectra for oleate-LFABP complexes, indicating that two molecules of the fatty acid are situated in the protein cavity. Carbon 21-22 fatty acid binding protein 1 Rattus norvegicus 93-98 11912238-12 2002 Consequently, wild-type plants growing in unfavourable light regimes and antisense RBCS transformants are simultaneously carbon- and nitrogen-limited. Carbon 121-127 ribulose bisphosphate carboxylase small chain S41, chloroplastic Nicotiana tabacum 83-87 11941464-8 2002 IDH protein was also increased in the transformed plants with low Fd-GOGAT, suggesting that both IDH and ICDH are involved in the production of carbon skeletons (and ultimately alpha-ketoglutarate) necessary for the re-assimilation of NH4+. Carbon 144-150 isocitrate dehydrogenase [NADP] Nicotiana tabacum 97-100 11881988-1 2002 1"-C-Methyl analogues of adenosine and selective adenosine A(1) receptor agonists, such as N-[(1R)-1-methyl-2-phenylethyl]adenosine ((R)-PIA) and N(6)-cyclopentyladenosine, were synthesized to further investigate the subdomain that binds the ribose moiety. Carbon 3-4 adenosine A1 receptor Rattus norvegicus 49-72 12027227-4 2002 Ex-tempore albumin-coating of carbon surface decreases adsorbent capacity by bilirubin on 21%. Carbon 30-36 albumin Homo sapiens 11-18 12027227-5 2002 At the same time ex-tempore albumin-coating of HSGD carbon surface as well as blood citratization prevent platelet and leukocytes loss and clotting inside of the column. Carbon 52-58 albumin Homo sapiens 28-35 12027227-7 2002 Combination of albumin-coated HSGD carbon as haemosorbent with HSA ligand-free solution as a transfusion media seems a new prospective modality of the extracorporeal removal of protein-bound toxins. Carbon 35-41 albumin Homo sapiens 15-22 12702322-2 2002 In previous studies we have found that the genes encoding the unique components of this complex (GCV1, GCV2 and GCV3) are regulated by the one-carbon status of the cell. Carbon 143-149 glycine decarboxylase subunit T Saccharomyces cerevisiae S288C 97-101 21782587-4 2002 Aroclors 1242 and 1248, 2,2",3,5",6-pentachlorobiphenyl (PCB 95), 2,2"-dichlorobiphenyl (PCB), cis- and trans- permethrins, and chlorothalonil were found to render estrogenic effects through this c-Neu-mediated mechanism, while alpha and beta- endosulfans appeared to act through a pathway independent of the c-Neu-mediated one. Carbon 3-4 pyruvate carboxylase Homo sapiens 57-60 11849480-0 2002 The value of the (1-84) PTH/C-PTH ratio for the diagnosis of low bone turnover in dialysis patients. Carbon 28-29 parathyroid hormone Homo sapiens 30-33 11924859-4 2002 At low nitrogen levels, the removal rate increased with increasing N:C ratio for both NH3 and NO3. Carbon 69-70 NBL1, DAN family BMP antagonist Homo sapiens 94-97 11880504-2 2002 We tested the hypothesis that impaired one-carbon metabolism resulting from folic acid deficiency and high homocysteine levels promotes accumulation of DNA damage and sensitizes neurons to amyloid beta-peptide (Abeta) toxicity. Carbon 43-49 amyloid beta precursor protein Homo sapiens 211-216 11825585-0 2002 P-glycoprotein inserted in planar lipid bilayers formed by liposomes opened on amorphous carbon and Langmuir-Blodgett monolayer. Carbon 89-95 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 12188021-9 2002 Binding to largely hydrophobic sites, such as the active site of p38, was significantly improved by introducing a correction factor selectively affecting only carbon and hydrogen energy grids, thus, providing an effective, although approximate, treatment of solvation. Carbon 159-165 mitogen-activated protein kinase 14 Homo sapiens 65-68 11786364-0 2002 Direct electrochemistry of catalase on glassy carbon electrodes. Carbon 46-52 catalase Homo sapiens 27-35 11677234-0 2002 Control of prostaglandin stereochemistry at the 15-carbon by cyclooxygenases-1 and -2. Carbon 51-57 prostaglandin-endoperoxide synthase 1 Homo sapiens 61-85 11925034-0 2002 Antisense repression of cytosolic phosphoglucomutase in potato (Solanum tuberosum) results in severe growth retardation, reduction in tuber number and altered carbon metabolism. Carbon 159-165 phosphoglucomutase Solanum tuberosum 34-52 11830405-1 2002 If forests are to be used in CO2 mitigation projects, it is essential to understand and quantify the impacts of disturbance on net ecosystem productivity (NEP; i.e., the change in ecosystem carbon (C) storage with time). Carbon 190-196 membrane metalloendopeptidase Homo sapiens 155-158 11853971-5 2002 The selected single chain variable fragment (scFv) bound specifically to a 16 carbon aliphatic chain and to a lesser extent to a 14 or 18 carbon aliphatic chain and poorly to either 12, 22 or 8 carbon aliphatic chains. Carbon 78-84 immunglobulin heavy chain variable region Homo sapiens 45-49 11853971-5 2002 The selected single chain variable fragment (scFv) bound specifically to a 16 carbon aliphatic chain and to a lesser extent to a 14 or 18 carbon aliphatic chain and poorly to either 12, 22 or 8 carbon aliphatic chains. Carbon 138-144 immunglobulin heavy chain variable region Homo sapiens 45-49 11853971-5 2002 The selected single chain variable fragment (scFv) bound specifically to a 16 carbon aliphatic chain and to a lesser extent to a 14 or 18 carbon aliphatic chain and poorly to either 12, 22 or 8 carbon aliphatic chains. Carbon 138-144 immunglobulin heavy chain variable region Homo sapiens 45-49 11786364-1 2002 Catalase was investigated as a possible catalyst of the electrochemical reduction of oxygen on glassy carbon electrodes. Carbon 102-108 catalase Homo sapiens 0-8 12968719-2 2002 The studies showed that PNP was not degraded as a sole carbon source in the reactor. Carbon 55-61 purine nucleoside phosphorylase Homo sapiens 24-27 11806528-5 2002 Experimental results indicated that the pre-ozonation could reduce the concentration of dissolved organic carbon resulting in the reduction of DBP formation. Carbon 106-112 D-box binding PAR bZIP transcription factor Homo sapiens 143-146 12968719-5 2002 However the total organic carbon (TOC) removals were 76.3% indicating the possibility of biotransformation of PNP. Carbon 26-32 purine nucleoside phosphorylase Homo sapiens 110-113 11813080-1 2002 The vitamins folic acid, B12 and B6 and B2 are the source of coenzymes which participate in one carbon metabolism. Carbon 96-102 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 25-42 16233204-4 2002 The maximum NO3-N removal rate was 0.46 kg-Nm(-3)d(-1) at an HRT of 0.75 h. Nitrogen removal efficiency of 99.5% at an HRT of 1 h was obtained with a C/N ratio 2.58, corresponding to 4.3 g of soluble starch per 1 g of NO3-N. Carbon 150-151 NBL1, DAN family BMP antagonist Homo sapiens 12-15 16233204-4 2002 The maximum NO3-N removal rate was 0.46 kg-Nm(-3)d(-1) at an HRT of 0.75 h. Nitrogen removal efficiency of 99.5% at an HRT of 1 h was obtained with a C/N ratio 2.58, corresponding to 4.3 g of soluble starch per 1 g of NO3-N. Carbon 150-151 NBL1, DAN family BMP antagonist Homo sapiens 218-221 12630782-5 2002 The post-processed ESI spectrum has quality as good as that of a probe-acquired spectrum and makes semi-quantitative analysis of the two-dimensional sp2/sp3 ratio map in diamond-like carbon thin film possible. Carbon 183-189 Sp2 transcription factor Homo sapiens 149-152 12630782-5 2002 The post-processed ESI spectrum has quality as good as that of a probe-acquired spectrum and makes semi-quantitative analysis of the two-dimensional sp2/sp3 ratio map in diamond-like carbon thin film possible. Carbon 183-189 Sp3 transcription factor Homo sapiens 153-156 11741859-9 2002 This is in contrast to Saccharomyces cerevisiae, where Cat8p and Sip4p, homologs of FacB, regulate PEPCK as well as the expression of other genes necessary for growth on nonfermentable carbon sources in response to the carbon source present. Carbon 185-191 Sip4p Saccharomyces cerevisiae S288C 65-70 11741859-9 2002 This is in contrast to Saccharomyces cerevisiae, where Cat8p and Sip4p, homologs of FacB, regulate PEPCK as well as the expression of other genes necessary for growth on nonfermentable carbon sources in response to the carbon source present. Carbon 219-225 Sip4p Saccharomyces cerevisiae S288C 65-70 15100872-0 2001 A voltammetric study of direct electron transfer to cytochrome c using a very large assembly of carbon microelectrodes. Carbon 96-102 cytochrome c, somatic Homo sapiens 52-64 11752218-3 2002 In the present study, 1,Omega-diols with 3 to 14 carbon atoms inhibited NMDA-activated current in Chinese hamster ovary and human embryonic kidney 293 cells transiently expressing NR1 and NR2B NMDA receptor subunits. Carbon 49-55 glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens 180-183 12201103-7 2002 The studies have shown that substantial removals of COD, NO3-N and NH3-N from both wastewater and river water may be achieved via adsorption-biodegradation by biofilm on activated carbon processes. Carbon 180-186 NBL1, DAN family BMP antagonist Homo sapiens 57-60 11733115-6 2001 Recently, it was found that PHA producing bacteria are able to grow simultaneously limited by carbon and nitrogen substrates. Carbon 94-100 lamin B receptor Homo sapiens 28-31 21669645-4 2001 An active malate dehydrogenase is required to facilitate carbon flow from phosphoenolpyruvate to oxaloacetate. Carbon 57-63 malate dehydrogenase Glycine max 10-30 11685512-0 2001 Both pH and carbon flux influence the level of rubredoxin in Clostridium butyricum. Carbon 12-18 ATN24_RS06715 Clostridium butyricum 47-57 11685512-2 2001 In this way, we showed that variations in rubredoxin content and in rub mRNA level were influenced by the pH of the culture and were directly dependent on the carbon flux. Carbon 159-165 ATN24_RS06715 Clostridium butyricum 42-52 11675150-7 2001 The estimated relative risk for lung cancer associated to a single mutated allele in CYP1A1, CYP2E1 or GSTM1 was 2.41 for m2, 1.69 for val, 1.16 for C, 0.71 for c2 and 2.46 for GSTM1(-). Carbon 85-86 glutathione S-transferase mu 1 Homo sapiens 103-108 11675150-7 2001 The estimated relative risk for lung cancer associated to a single mutated allele in CYP1A1, CYP2E1 or GSTM1 was 2.41 for m2, 1.69 for val, 1.16 for C, 0.71 for c2 and 2.46 for GSTM1(-). Carbon 85-86 glutathione S-transferase mu 1 Homo sapiens 177-182 11763260-2 2001 The PCB distribution has been correlated with location and hydrological conditions as well as with organic carbon, algal pigments and their derivatives in the sediments. Carbon 107-113 pyruvate carboxylase Homo sapiens 4-7 15100872-1 2001 A very large assembly of more than 8000 carbon fibre microdisk electrodes was used to study direct electron transfer to cytochrome c. Carbon 40-46 cytochrome c, somatic Homo sapiens 120-132 11705390-6 2001 These results support a model for a single common binding site for halides and thiocyanate as substrates or as inhibitors near the delta-meso carbon of the porphyrin ring in myeloperoxidase. Carbon 142-148 myeloperoxidase Homo sapiens 174-189 11849593-2 2001 To investigate whether the MP17-induced alteration in carbon metabolism is related to the targeting and modification of specific plasmodesmata (Pd) or is rather due to pleiotropic effects caused by high MP17 protein amounts, non-phenotypic tobacco plants expressing a MP17:GFP fusion protein were obtained and compared with previously described MP17 transgenic lines. Carbon 54-60 lens intrinsic membrane protein 2 Homo sapiens 27-31 11562373-7 2001 Analysis of the relative levels of these proteins revealed that the expression of GDH1 and GDH3 is differentially regulated and depends on the nature of the carbon source. Carbon 157-163 glutamate dehydrogenase (NADP(+)) GDH3 Saccharomyces cerevisiae S288C 91-95 11816594-0 2001 Carbon electrodes modified with ruthenium metallodendrimer multilayers for the mediated oxidation of methionine and insulin at physiological pH. Carbon 0-6 insulin Homo sapiens 116-123 11524424-1 2001 ADP-glucose pyrophosphorylase (AGPase) is a key regulatory enzyme of bacterial glycogen and plant starch synthesis as it controls carbon flux via its allosteric regulatory behavior. Carbon 130-136 glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic/amyloplastic Solanum tuberosum 0-29 11524424-1 2001 ADP-glucose pyrophosphorylase (AGPase) is a key regulatory enzyme of bacterial glycogen and plant starch synthesis as it controls carbon flux via its allosteric regulatory behavior. Carbon 130-136 glucose-1-phosphate adenylyltransferase large subunit 2, chloroplastic/amyloplastic Solanum tuberosum 31-37 11910758-1 2001 In order to enhance the expression level of human trefoil factor 3 (hTFF3) in Pichia pastoris, we optimized the transformant growth conditions in shake flasks including carbon sources in growth medium, inoculation ratio, methanol concentration, pH rotation speed and inducing time. Carbon 169-175 trefoil factor 3 Homo sapiens 50-66 11910758-1 2001 In order to enhance the expression level of human trefoil factor 3 (hTFF3) in Pichia pastoris, we optimized the transformant growth conditions in shake flasks including carbon sources in growth medium, inoculation ratio, methanol concentration, pH rotation speed and inducing time. Carbon 169-175 trefoil factor 3 Homo sapiens 68-73 11682009-1 2001 PURPOSE: To investigate the dependence on p53 gene status of the thermal enhancement of cellular sensitivity against different levels of linear energy transfer (LET) from X-rays or carbon-ion (C-) beams. Carbon 181-187 tumor protein p53 Homo sapiens 42-45 11596746-6 2001 For LAS, the organic carbon-based partition coefficient values were between 2.4 x 10(3) and 6.6 x 10(5)L/kg for the C10 and C13 homologues, respectively; these values are similar to those obtained from laboratory tests for the sorption of LAS onto marine sediments. Carbon 21-27 homeobox C10 Homo sapiens 116-119 11589968-5 2001 Transfer nuclear Overhauser enhancement NMR experiments indicate the existence of dipolar interactions at short interatomic distances between C-1 proton of D-glucose in the beta form and the monomeric insulin. Carbon 142-143 insulin Homo sapiens 201-208 11486018-1 2001 Sip4 is a Zn(2)Cys(6) transcriptional activator that binds to the carbon source-responsive elements of gluconeogenic genes in Saccharomyces cerevisiae. Carbon 66-72 Sip4p Saccharomyces cerevisiae S288C 0-4 11486018-4 2001 We show that Srb10 is required for phosphorylation of Sip4 during growth in nonfermentable carbon sources and that the catalytic activity of Srb10 stimulates the ability of LexA-Sip4 to activate transcription of a reporter. Carbon 91-97 Sip4p Saccharomyces cerevisiae S288C 54-58 11544037-2 2001 The sensor is based on a carbon paste electrode containing genetically engineered cells expressing organophosphorus hydrolase (OPH) on the cell surface. Carbon 25-31 acylaminoacyl-peptide hydrolase Homo sapiens 99-125 11544037-2 2001 The sensor is based on a carbon paste electrode containing genetically engineered cells expressing organophosphorus hydrolase (OPH) on the cell surface. Carbon 25-31 acylaminoacyl-peptide hydrolase Homo sapiens 127-130 11828488-1 2001 The detection and assignment of NMR spectroscopic signals of carbon atoms from carbonyl and carboxylate groups in the loop hosting the Ce(III) ion was performed for the cerium-substituted calcium-binding protein calbindin D9k. Carbon 61-67 S100 calcium binding protein G Homo sapiens 212-225 11486018-4 2001 We show that Srb10 is required for phosphorylation of Sip4 during growth in nonfermentable carbon sources and that the catalytic activity of Srb10 stimulates the ability of LexA-Sip4 to activate transcription of a reporter. Carbon 91-97 Sip4p Saccharomyces cerevisiae S288C 178-182 16120277-5 2001 Quantitation of relative fluorescence by flow cytometry confirmed that cox3 :: GFP(m)-3 expression was affected by carbon source and dependent upon COX3 mRNA-specific translational activation. Carbon 115-121 cytochrome c oxidase subunit 3 Saccharomyces cerevisiae S288C 71-75 11461776-6 2001 For equine myoglobin, it is found that adduct formation involves a single residue-Tyr-103 and further that adduct formation occurs at the C-3 carbon of the amino acid. Carbon 142-148 myoglobin Equus caballus 11-20 11466067-4 2001 Crystal data for 1: C(78)H(142)Cl(2)Mg(4)O(26)Si(14).6(C(4)H(8)O), a = 15.744(1) A, b = 26.526(2) A, c = 16.917(1) A, beta = 113.229(2) degrees, monoclinic, P2(1)/n, Z = 2. Carbon 0-1 cyclin dependent kinase inhibitor 1A Homo sapiens 157-162 11461648-1 2001 We have explored the cohesive property of a monolayer of C (60) molecules (ML- C (60)) by means of total energy calculations with the density-functional theory. Carbon 57-58 modulator of VRAC current 1 Homo sapiens 75-80 11454749-0 2001 The defect in transcription-coupled repair displayed by a Saccharomyces cerevisiae rad26 mutant is dependent on carbon source and is not associated with a lack of transcription. Carbon 112-118 DNA-dependent ATPase RAD26 Saccharomyces cerevisiae S288C 83-88 11724283-6 2001 Two CEM drug-resistant clones, CEM/ara-C/G/ASNase-0.5-1 and CEM/ara-C/G/ASNase-1-1, lacked VEGF production. Carbon 4-5 asparaginase and isoaspartyl peptidase 1 Homo sapiens 43-49 11525399-3 2001 Expression of GRE3 is carbon-source independent and up-regulated by different stress conditions, such as NaCl, H2O2, 39 degrees C and carbon starvation. Carbon 22-28 trifunctional aldehyde reductase/xylose reductase/glucose 1-dehydrogenase (NADP(+)) Saccharomyces cerevisiae S288C 14-18 11525399-3 2001 Expression of GRE3 is carbon-source independent and up-regulated by different stress conditions, such as NaCl, H2O2, 39 degrees C and carbon starvation. Carbon 134-140 trifunctional aldehyde reductase/xylose reductase/glucose 1-dehydrogenase (NADP(+)) Saccharomyces cerevisiae S288C 14-18 18968331-2 2001 Tyrosinase and horse-radish peroxidase were immobilized on the surface of a glassy carbon electrode by bovine serum albumin and glutaric dialdehyde. Carbon 83-89 tyrosinase Equus caballus 0-10 11454749-8 2001 We therefore measured the level of repair and transcription in two different carbon sources and found that the defect in the rad26 mutant for TCR was dependent on the type of carbon source. Carbon 77-83 DNA-dependent ATPase RAD26 Saccharomyces cerevisiae S288C 125-130 11454749-8 2001 We therefore measured the level of repair and transcription in two different carbon sources and found that the defect in the rad26 mutant for TCR was dependent on the type of carbon source. Carbon 175-181 DNA-dependent ATPase RAD26 Saccharomyces cerevisiae S288C 125-130 11444938-11 2001 For deuterons attached to sp2 carbons, first, the asymmetry factors eta and, second, the quadrupole coupling constants C(Q), are unusually small, eta1=0.018, eta2=0.011, and C(Q1)=(151.27+/-0.06) kHz, C(Q2)=(154.09+/-0.06) kHz. Carbon 30-37 Sp2 transcription factor Homo sapiens 26-29 11395250-0 2001 High linear energy transfer carbon radiation effectively kills cultured glioma cells with either mutant or wild-type p53. Carbon 28-34 tumor protein p53 Homo sapiens 117-120 11395250-8 2001 The effects of the carbon beams were not dependent on the p53 gene status but were reduced by G(1) arrest, which was independent of p21 expression. Carbon 19-25 tumor protein p53 Homo sapiens 58-61 11402203-4 2001 Plant lines with Fru-2,6-P(2) levels down to 5% of the levels observed in wild-type (WT) plants had significantly altered partitioning of carbon between sucrose (Suc) versus starch. Carbon 138-144 FER-like regulator of iron uptake Arabidopsis thaliana 17-20 11419873-1 2001 Recent developments in thin film technology allow to prepare deliberately amorphous carbon films with structures widely varying between graphite-like (sp2) and diamond-like (sp3) atomic bonds. Carbon 84-90 Sp2 transcription factor Homo sapiens 151-154 11419873-1 2001 Recent developments in thin film technology allow to prepare deliberately amorphous carbon films with structures widely varying between graphite-like (sp2) and diamond-like (sp3) atomic bonds. Carbon 84-90 Sp3 transcription factor Homo sapiens 174-177 11453675-9 2001 Loading with carbon further aggravated the effect of IFN-gamma. Carbon 13-19 interferon gamma Homo sapiens 53-62 11485170-5 2001 The nitrogen atom attached to the carbon cage formed a "[5,6]open" type aza substructure, which was confirmed by the appearance of 31-32 signals in the region of deltaC 133-148 (carbon shifts of Sp2 carbons of the cage) in the 13C nuclear magnetic resonance spectra. Carbon 34-40 Sp2 transcription factor Homo sapiens 195-198 11485170-5 2001 The nitrogen atom attached to the carbon cage formed a "[5,6]open" type aza substructure, which was confirmed by the appearance of 31-32 signals in the region of deltaC 133-148 (carbon shifts of Sp2 carbons of the cage) in the 13C nuclear magnetic resonance spectra. Carbon 178-184 Sp2 transcription factor Homo sapiens 195-198 11485170-5 2001 The nitrogen atom attached to the carbon cage formed a "[5,6]open" type aza substructure, which was confirmed by the appearance of 31-32 signals in the region of deltaC 133-148 (carbon shifts of Sp2 carbons of the cage) in the 13C nuclear magnetic resonance spectra. Carbon 199-206 Sp2 transcription factor Homo sapiens 195-198 11402203-10 2001 Our data provide direct evidence that Fru-2,6-P(2) affects photosynthetic carbon partitioning in Arabidopsis. Carbon 74-80 FER-like regulator of iron uptake Arabidopsis thaliana 38-41 11352748-4 2001 In this study, a series of unbranched p-nitroanilide (pNA) substrates ranging from 6 to 20 carbons in length was used to probe the acyl chain binding specificity of FAAH, revealing that this enzyme exhibits a strong preference for acyl chains 9 carbons in length or longer. Carbon 91-98 fatty acid amide hydrolase Homo sapiens 165-169 18968291-5 2001 The best sample loading flow rate was 4.0 ml min(-1) for the activated carbon and 2.0 ml min(-1) for C(18) and the polyurethane foam, while the best elution flow rate was 1.0 ml min(-1) (activated carbon) and 0.6 ml min(-1) (C(18) and foam). Carbon 101-102 CD59 molecule (CD59 blood group) Homo sapiens 89-95 18968291-5 2001 The best sample loading flow rate was 4.0 ml min(-1) for the activated carbon and 2.0 ml min(-1) for C(18) and the polyurethane foam, while the best elution flow rate was 1.0 ml min(-1) (activated carbon) and 0.6 ml min(-1) (C(18) and foam). Carbon 101-102 CD59 molecule (CD59 blood group) Homo sapiens 89-95 18968291-5 2001 The best sample loading flow rate was 4.0 ml min(-1) for the activated carbon and 2.0 ml min(-1) for C(18) and the polyurethane foam, while the best elution flow rate was 1.0 ml min(-1) (activated carbon) and 0.6 ml min(-1) (C(18) and foam). Carbon 101-102 CD59 molecule (CD59 blood group) Homo sapiens 89-95 11352748-4 2001 In this study, a series of unbranched p-nitroanilide (pNA) substrates ranging from 6 to 20 carbons in length was used to probe the acyl chain binding specificity of FAAH, revealing that this enzyme exhibits a strong preference for acyl chains 9 carbons in length or longer. Carbon 245-252 fatty acid amide hydrolase Homo sapiens 165-169 11354475-2 2001 In basic media, these monomers self-polymerize via a series of nucleophilic aromatic substitution reactions (SNAr), in which aromatic enolates (ArO- nucleophiles) attack the electrophilic carbons bearing F leaving groups to effect fluoride displacement. Carbon 188-195 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 144-147 11393426-1 2001 The adsorption behaviour of Diphenylamine (DPAM), beta napthylamine (beta NAM), alpha napthylamine (alpha NAM) and aniline on pyrolusite and activated carbon has been studied. Carbon 151-157 SH3 and cysteine rich domain 3 Homo sapiens 74-77 11386857-0 2001 Utilization of an alternative carbon source for efficient production of human alpha(1)-antitrypsin by genetically engineered rice cell culture. Carbon 30-36 serpin family A member 1 Homo sapiens 78-98 11386857-2 2001 Batch and continuous cultures were employed to investigate the effects of alternative carbon sources on the alpha(1)-antitrypsin production. Carbon 86-92 serpin family A member 1 Homo sapiens 108-128 11386857-3 2001 While this expression system is inducible by sugar depletion, we have found that the productivity of alpha(1)-antitrypsin increased 2.4- to 3.4-fold, compared with the control medium without carbon source, in medium containing an alternative carbon source, such as pyruvic acid and glyoxylic acid. Carbon 191-197 serpin family A member 1 Homo sapiens 101-121 11386857-3 2001 While this expression system is inducible by sugar depletion, we have found that the productivity of alpha(1)-antitrypsin increased 2.4- to 3.4-fold, compared with the control medium without carbon source, in medium containing an alternative carbon source, such as pyruvic acid and glyoxylic acid. Carbon 242-248 serpin family A member 1 Homo sapiens 101-121 11353537-7 2001 In addition, among these OVA-liposomes, the one possessing the longest carbon chain induced the lowest IgG antibody production. Carbon 71-77 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 25-28 11409176-6 2001 Thus, the HSP26 and the HSP30 promoter can be used for late, phase-specific expression of the desired genes with glucose or maltose as carbon source, and HSP12 with glucose only. Carbon 135-141 Hsp30p Saccharomyces cerevisiae S288C 24-29 11393426-1 2001 The adsorption behaviour of Diphenylamine (DPAM), beta napthylamine (beta NAM), alpha napthylamine (alpha NAM) and aniline on pyrolusite and activated carbon has been studied. Carbon 151-157 SH3 and cysteine rich domain 3 Homo sapiens 106-109 11393426-3 2001 The effect of various doses of activated carbon on the adsorption of beta NAM confirm Langmuir and Freundlich isotherms where as Freundlich isotherm is obeyed by pyrolusite. Carbon 41-47 SH3 and cysteine rich domain 3 Homo sapiens 74-77 23696487-0 2001 Detection of the linear carbon cluster C10: rotationally resolved diode-laser spectroscopy. Carbon 24-30 homeobox C10 Homo sapiens 39-42 11338597-7 2001 In this study, we used the T3C combination of a carbon and a conventional bonded phase for the separation of barbiturates and phenylthiohydantoin amino acids (PTH-amino acids). Carbon 48-54 parathyroid hormone Homo sapiens 159-162 23696487-2 2001 A high-resolution infrared spectrometer housing a tunable diode laser and combined with an effective laser ablation source for the cluster production has been used to study the molecular properties of small carbon clusters; reported herein is the first gas-phase spectrum of linear C10. Carbon 207-213 homeobox C10 Homo sapiens 282-285 11405098-0 2001 Contribution of Cat8 and Sip4 to the transcriptional activation of yeast gluconeogenic genes by carbon source-responsive elements. Carbon 96-102 Sip4p Saccharomyces cerevisiae S288C 25-29 11795521-6 2001 Muscle glutamine synthetase mRNA increased 1.3- and 2.1-fold in young and old CR mice, suggesting increased disposal of nitrogen and carbon derived from protein catabolism for energy. Carbon 133-139 glutamate-ammonia ligase (glutamine synthetase) Mus musculus 7-27 11457071-4 2001 MP2 and DFT (B3LYP) calculations predict, for the noncatalyzed reaction, a central barrier of approximately 20-21 kcal/mol separating the reactants from products depending on which carbon center in the epoxide is undergoing attack. Carbon 181-187 proline rich protein HaeIII subfamily 1 Mus musculus 0-3 11309260-8 2001 Interestingly, L-MIT-D-Phe (MIDF) showed little inhibitory activity or selectivity, suggesting that the cavity of human iNOS is located in a well-defined direction from the alpha carbon atom. Carbon 179-185 nitric oxide synthase 2 Homo sapiens 120-124 11310677-3 2001 The mechanism of the nitrosation of enolate anion of acetone [CH3COCH2]- (1) with methyl nitrite CH3ONO (2) via an "open-chain" transition state without Na+ in the C-N bond formation process was studied by the ab initio MO method. Carbon 62-63 cochlin Homo sapiens 65-69 11160627-4 2001 ERK activation induced by the PKC activator phorbol myristate acetate was inhibited by PTX, PP1, AG1478, and calphostin C. Carbon 32-33 mitogen-activated protein kinase 1 Homo sapiens 0-3 15348300-1 2001 In order to evaluate if carbon coated polyethylene terephthalate (C-PET) could favor inflammatory reactions, the expression of interleukin-6 (IL-6) by cultured human umbilical vein endothelial cells was tested in vitro. Carbon 24-30 interleukin 6 Homo sapiens 127-140 15348300-1 2001 In order to evaluate if carbon coated polyethylene terephthalate (C-PET) could favor inflammatory reactions, the expression of interleukin-6 (IL-6) by cultured human umbilical vein endothelial cells was tested in vitro. Carbon 66-67 interleukin 6 Homo sapiens 127-140 11345253-5 2001 Good agreement is found for the band positions of carbon chains containing odd C15-C21 neutrals and even C6(-)-C22- anions, with species previously identified by Maier and coworkers using mass selection or laser vaporization, followed by neon matrix isolation. Carbon 50-56 TBL1X/Y related 1 Homo sapiens 83-86 11345253-9 2001 Comparison of the 0(0)0 absorption transitions of the even C18(-)-C36- anionic clusters with the "unidentified" infrared (UIR) interstellar emission bands suggests that the electronic emission from specific long chain carbon anions may contribute to the some of the UIR bands. Carbon 218-224 Bardet-Biedl syndrome 9 Homo sapiens 59-62 11456893-0 2001 Direct observation of protein vibrations by selective incorporation of spectroscopically observable carbon-deuterium bonds in cytochrome c. Carbon 100-106 cytochrome c, somatic Homo sapiens 126-138 11222741-11 2001 The flexibility of the polar region in the TRbeta receptor, combined with differential recognition of the chemical group at the 1-carbon position, seems to stabilize the complex with GC-1 and contribute to its beta-selectivity. Carbon 130-136 T cell receptor beta locus Homo sapiens 43-49 11254338-0 2001 Thermally Induced Transient Activity Changes of Plasmin Adsorbed onto Bare and Fibrinogen-Modified Graphite and Glassy Carbon Surfaces. Carbon 119-125 fibrinogen beta chain Homo sapiens 79-89 11383693-5 2001 These results suggest that FA regulate the gene expression of CETP in HepG2 and this effect is dependent upon the degree of unsaturation of the acyl carbon chain in FA. Carbon 149-155 cholesteryl ester transfer protein Homo sapiens 62-66 11383696-3 2001 This was confirmed by the appearance of 30-31 sp2 signals at deltac 133-147 in the carbon nuclear magnetic resonance spectra. Carbon 83-89 Sp2 transcription factor Homo sapiens 46-49 11067851-10 2001 Both C- and O-glycosylations take place on residues that have been implicated in the interaction of TSP-1 with glycosaminoglycans or other cellular receptors. Carbon 5-6 thrombospondin 1 Homo sapiens 100-105 11223170-6 2001 Both the resulting core carbon particles and the organic extract enhanced ovalbumin specific IgE and IgG1 levels. Carbon 24-30 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 74-83 11456705-6 2001 Low-temperature EPR analysis coupled with parallel spin-trapping investigations following the reaction of the PS2.M--hemin complex and hydrogen peroxide (H(2)O(2)) indicated the formation of a carbon-centered radical, most likely on the PS2.M oligonucleotide. Carbon 193-199 taste 2 receptor member 64 pseudogene Homo sapiens 110-113 11456705-6 2001 Low-temperature EPR analysis coupled with parallel spin-trapping investigations following the reaction of the PS2.M--hemin complex and hydrogen peroxide (H(2)O(2)) indicated the formation of a carbon-centered radical, most likely on the PS2.M oligonucleotide. Carbon 193-199 taste 2 receptor member 64 pseudogene Homo sapiens 237-240 11160627-4 2001 ERK activation induced by the PKC activator phorbol myristate acetate was inhibited by PTX, PP1, AG1478, and calphostin C. Carbon 32-33 neuropeptide Y receptor Y4 Homo sapiens 92-95 11013234-6 2001 The expression of Odc1p, the more abundant isoform, made in the presence of nonfermentable carbon sources, is repressed by glucose. Carbon 91-97 mitochondrial 2-oxodicarboxylate carrier Saccharomyces cerevisiae S288C 18-23 11158356-0 2001 Pyruvate kinase (Pyk1) levels influence both the rate and direction of carbon flux in yeast under fermentative conditions. Carbon 71-77 pyruvate kinase CDC19 Saccharomyces cerevisiae S288C 17-21 11158356-8 2001 Unexpectedly, the reduced Pyk1 levels caused the flow of carbon to the TCA cycle to increase, even under fermentative growth conditions. Carbon 57-63 pyruvate kinase CDC19 Saccharomyces cerevisiae S288C 26-30 11158356-9 2001 Therefore, Pyk1 exerts a significant level of control over both the rate and direction of carbon flux in yeast. Carbon 90-96 pyruvate kinase CDC19 Saccharomyces cerevisiae S288C 11-15 11169757-0 2001 Cat8 and Sip4 mediate regulated transcriptional activation of the yeast malate dehydrogenase gene MDH2 by three carbon source-responsive promoter elements. Carbon 112-118 Sip4p Saccharomyces cerevisiae S288C 9-13 11169757-3 2001 We demonstrate the importance of transcriptional activators Hap4, Cat8 and Pip2 for the carbon source-dependent regulation of MDH1, MDH2 and MDH3, respectively. Carbon 88-94 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 75-79 11169757-3 2001 We demonstrate the importance of transcriptional activators Hap4, Cat8 and Pip2 for the carbon source-dependent regulation of MDH1, MDH2 and MDH3, respectively. Carbon 88-94 malate dehydrogenase MDH3 Saccharomyces cerevisiae S288C 141-145 11180563-5 2001 Kinetic rates for the binding of bovine pancreatic ribonuclease A (RNase A), monoacylated on its N-terminal lysine with fatty acids of 10, 12, 14, 16 or 18 carbon atoms, to phospholipids on hydrophobic sensor chips, were measured. Carbon 156-162 ribonuclease pancreatic Bos taurus 51-65 11115644-8 2001 Thus, experiments can be performed in the presence of non-limiting amounts of carbon substrate, an approach which has been successfully applied to slow growing cells such as yeast cells expressing wild-type or a mutant rat uncoupling protein-1. Carbon 78-84 uncoupling protein 1 Rattus norvegicus 223-243 11072229-3 2001 We have also studied biosynthetically carbon-13 methyl-Met calmodulin by (1)H, (13)C heteronuclear multiple quantum coherence NMR spectroscopy. Carbon 38-44 calmodulin 1 Homo sapiens 59-69 11197161-1 2001 Capillary zone electrophoresis was employed for the determination of human serum transferrin using end-column amperometric detection with a carbon fiber microelectrode at a constant potential of 1.9 V vs. saturated calomel electrode (SCE). Carbon 140-146 transferrin Homo sapiens 81-92 11180563-5 2001 Kinetic rates for the binding of bovine pancreatic ribonuclease A (RNase A), monoacylated on its N-terminal lysine with fatty acids of 10, 12, 14, 16 or 18 carbon atoms, to phospholipids on hydrophobic sensor chips, were measured. Carbon 156-162 ribonuclease pancreatic Bos taurus 67-74 11171166-1 2000 The Arabidopsis mutants designated gly1 exhibit a reduced carbon flux through the prokaryotic pathway that is compensated for by an increased carbon flux through the eukaryotic pathway. Carbon 58-64 NAD-dependent glycerol-3-phosphate dehydrogenase family protein Arabidopsis thaliana 35-39 11329881-6 2001 Signal peptide of suc2 and alpha chain of human interleukin-2 was fused in frame to suc2 gene, then the two resulting vectors were transformed into EGY48-delta suc, all the transformants can grow in the medium with either raffinose or glucose as carbon source. Carbon 246-252 interleukin 2 Homo sapiens 48-61 11603298-2 2000 FI0-c, and its sulfated derivative, FI0-c-S, on production of human proinflammatory cytokines, interleukin-1 alpha (IL-1 alpha) and tumor necrosis factor alpha (TNF alpha). Carbon 4-5 tumor necrosis factor Homo sapiens 132-159 11171165-0 2000 Role of acyl-CoAs and acyl-CoA-binding protein in regulation of carbon supply for fatty acid biosynthesis. Carbon 64-70 diazepam binding inhibitor, acyl-CoA binding protein Homo sapiens 22-46 11171166-1 2000 The Arabidopsis mutants designated gly1 exhibit a reduced carbon flux through the prokaryotic pathway that is compensated for by an increased carbon flux through the eukaryotic pathway. Carbon 142-148 NAD-dependent glycerol-3-phosphate dehydrogenase family protein Arabidopsis thaliana 35-39 11237093-3 2000 We report here the synthesis and study of the new unsymmetrical azo compounds SA-1, SA-2, C-16, C-12, and C-8 that decompose over a range of convenient temperatures and improve radical generation efficiency and access to lipid compartments. Carbon 90-91 stromal antigen 1 Homo sapiens 78-82 11082192-1 2000 In Saccharomyces cerevisiae, the existence of PYC1 and PYC2 encoding cytosolic pyruvate carboxylase isoform I and II is rather puzzling, owing to the lack of potent differential gene regulation by the carbon sources. Carbon 201-207 pyruvate carboxylase 2 Saccharomyces cerevisiae S288C 55-59 11102785-1 2000 The enzyme transketolase has been employed as a catalyst for asymmetric carbon-carbon bond formation in the synthesis of biologically important molecules. Carbon 72-78 transketolase Homo sapiens 11-24 11102785-1 2000 The enzyme transketolase has been employed as a catalyst for asymmetric carbon-carbon bond formation in the synthesis of biologically important molecules. Carbon 79-85 transketolase Homo sapiens 11-24 11237093-3 2000 We report here the synthesis and study of the new unsymmetrical azo compounds SA-1, SA-2, C-16, C-12, and C-8 that decompose over a range of convenient temperatures and improve radical generation efficiency and access to lipid compartments. Carbon 96-97 stromal antigen 1 Homo sapiens 78-82 11077306-6 2000 For example, distortion in the moiety C=C(O)(C) is exhibited by the enlargement of C=C-C angle to 130.6 (2) degrees at the expense of the corresponding "equivalent" C=C-O angle, which is compressed to 116.46 (19) degrees. Carbon 38-39 ryanodine receptor 1 Homo sapiens 165-170 11133047-4 2000 The accumulation of hsp72 and p53 was observed in A-172 cells after exposure to the conditioned medium of the T98G cells irradiated with accelerated carbon-ion beams, and the accumulation was abolished by the addition of an inhibitor for inducible nitric oxide synthase to the medium. Carbon 149-155 heat shock protein family A (Hsp70) member 1A Homo sapiens 20-25 11133047-4 2000 The accumulation of hsp72 and p53 was observed in A-172 cells after exposure to the conditioned medium of the T98G cells irradiated with accelerated carbon-ion beams, and the accumulation was abolished by the addition of an inhibitor for inducible nitric oxide synthase to the medium. Carbon 149-155 tumor protein p53 Homo sapiens 30-33 11153953-0 2000 Influence of surface carbon coverage of C1 (TMS) stationary phases on the separation of nonylphenol ethoxylate ethoxymers. Carbon 21-27 PYD and CARD domain containing Homo sapiens 44-47 11153953-4 2000 Here, we postulate that this phenomenon may be linked to carbon coverage of the C1 (TMS) stationary phases and study this utilising both elemental (bulk) analyses and surface specific analyses by X-ray photoelectron spectroscopy. Carbon 57-63 PYD and CARD domain containing Homo sapiens 84-87 11077306-6 2000 For example, distortion in the moiety C=C(O)(C) is exhibited by the enlargement of C=C-C angle to 130.6 (2) degrees at the expense of the corresponding "equivalent" C=C-O angle, which is compressed to 116.46 (19) degrees. Carbon 40-41 ryanodine receptor 1 Homo sapiens 165-170 11077306-6 2000 For example, distortion in the moiety C=C(O)(C) is exhibited by the enlargement of C=C-C angle to 130.6 (2) degrees at the expense of the corresponding "equivalent" C=C-O angle, which is compressed to 116.46 (19) degrees. Carbon 40-41 ryanodine receptor 1 Homo sapiens 165-170 10944191-6 2000 PS2 shows only a single broad and intense emissive signal, which is assigned to both the C-10 and C-15 methine carbon atoms. Carbon 111-117 taste 2 receptor member 64 pseudogene Homo sapiens 0-3 11053125-13 2000 This morphological evidence supports the hypothesis that activation of RyR3 in skeletal muscle cells must be indirect and provides the basis for failure of e-c coupling in muscle cells containing RyR3 but lacking RyR1 (see the accompanying report, ). Carbon 15-16 ryanodine receptor 3 Mus musculus 71-75 11027148-1 2000 The substitution of the C=O by the C=S group in 2-azaoctanoyl-CoA increases the volume of the ligand by 11 A(3), and the excision of a methylene group from Glu-376, via Glu-376 --> Asp (E376D) mutation in medium chain acyl-CoA dehydrogenase (MCAD), creates a complementary cavity of 18 A(3) dimension, just opposite to the ligand"s carbonyl group. Carbon 24-25 acyl-CoA dehydrogenase medium chain Homo sapiens 208-243 11027148-1 2000 The substitution of the C=O by the C=S group in 2-azaoctanoyl-CoA increases the volume of the ligand by 11 A(3), and the excision of a methylene group from Glu-376, via Glu-376 --> Asp (E376D) mutation in medium chain acyl-CoA dehydrogenase (MCAD), creates a complementary cavity of 18 A(3) dimension, just opposite to the ligand"s carbonyl group. Carbon 24-25 acyl-CoA dehydrogenase medium chain Homo sapiens 245-249 10998266-3 2000 Many different sialylated oligosaccharides of EPO were separated and characterized by LC/MS equipped with a graphitized carbon column (GCC). Carbon 120-126 erythropoietin Homo sapiens 46-49 10989879-5 2000 Captopril molecules are coordinated via mercapto group and amidic C=O group to Co(III) ions: two S atoms are bridging bonded between two Co(III) ions. Carbon 0-1 mitochondrially encoded cytochrome c oxidase III Homo sapiens 79-86 11007651-7 2000 A binding mode for pABA, sulfonamides and sulfones is suggested based on: (i) the new conformation of the closed loop 1; (ii) the distribution of dapsone and sulfonamide resistance mutations; (iii) the observed direction of the bond between the 6-methyl carbon atom and the bridging oxygen atom to the alpha-phosphate group in the Mtb DHPS:PtP binary complex; and (iv) the conformation of loop 2 in the Escherichia coli DHPS structure. Carbon 254-260 dihydropteroate synthetase Escherichia coli 335-339 11007651-7 2000 A binding mode for pABA, sulfonamides and sulfones is suggested based on: (i) the new conformation of the closed loop 1; (ii) the distribution of dapsone and sulfonamide resistance mutations; (iii) the observed direction of the bond between the 6-methyl carbon atom and the bridging oxygen atom to the alpha-phosphate group in the Mtb DHPS:PtP binary complex; and (iv) the conformation of loop 2 in the Escherichia coli DHPS structure. Carbon 254-260 dihydropteroate synthetase Escherichia coli 420-424 11041893-7 2000 The predicted CER6 amino acid sequence resembles that of fatty acid-condensing enzymes, consistent with its role in the production of epicuticular and pollen coat lipids >28 carbons long. Carbon 177-184 3-ketoacyl-CoA synthase 6 Arabidopsis thaliana 14-18 10974054-7 2000 Vitrified molecules of apoB were obtained by plunging a thin fluid layer of protein adhered to a holey carbon-coated grid into supercooled ethane and by preserving the molecules in liquid nitrogen. Carbon 103-109 apolipoprotein B Homo sapiens 23-27 10963678-5 2000 Furthermore, the effects of the bottom of the pocket mutation suggest that the autoreactive response could require an autologous ligand, and they indicate that alpha-GalCer binds to the groove of mCD1.1, most likely with the shorter 18-carbon hydrophobic chain in the A" pocket. Carbon 236-242 CD1d1 antigen Mus musculus 196-202 10924728-8 2000 Plasma CETP was inversely associated with HDL-C in men but not in women (P< 0.05 for the sex difference, multivariate analysis), inversely related to the HDL-C/apo A-1 ratio in men and positively related in women (P < 0.005 for the sex difference), and was positively associated with total cholesterol (TC) and low-density lipoprotein cholesterol in both sexes, and with the TC/HDL-C ratio and apo B in men alone. Carbon 45-47 cholesteryl ester transfer protein Homo sapiens 7-11 10955990-14 2000 Thus, the species Fe(C)Ti(N)-hTF might also provide a route for Ti(IV) entry into tumor cells via the transferrin receptor. Carbon 21-22 transferrin Homo sapiens 102-113 10959965-11 2000 The rate of electron transfer at sp2 carbon electrodes is known to be mediated by surface carbonyl functionalities; however, this inner-sphere, catalytic pathway is absent on diamond due to the hydrogen termination. Carbon 37-43 Sp2 transcription factor Homo sapiens 33-36 10970639-0 2000 Compressibility and polygonization of single-walled carbon nanotubes under hydrostatic pressure Single-walled carbon nanotubes show linear elasticity under hydrostatic pressure up to 1.5 GPa at room temperature. Carbon 110-116 glycophorin A (MNS blood group) Homo sapiens 187-190 10947125-0 2000 Induction by carbon-ion irradiation of the expression of vascular endothelial growth factor in lung carcinoma cells. Carbon 13-19 vascular endothelial growth factor A Homo sapiens 57-91 10947125-1 2000 PURPOSE: To investigate the induction by carbon- ion irradiation of vascular endothelial growth factor (VEGF) mRNA and protein. Carbon 41-47 vascular endothelial growth factor A Homo sapiens 68-102 10947125-1 2000 PURPOSE: To investigate the induction by carbon- ion irradiation of vascular endothelial growth factor (VEGF) mRNA and protein. Carbon 41-47 vascular endothelial growth factor A Homo sapiens 104-108 10947125-7 2000 Single doses of 15 Gy with either X-rays or carbon ions significantly induced VEGF mRNA expression at 16-24h after irradiation with a maximum induction of 2.81-fold. Carbon 44-50 vascular endothelial growth factor A Homo sapiens 78-82 10947125-8 2000 A significant increase was also observed in VEGF protein levels, detected in culture supernatant 24h after irradiation with 50 and 90keV/microm carbon ions. Carbon 144-150 vascular endothelial growth factor A Homo sapiens 44-48 10947125-10 2000 The induction of VEGF mRNA by carbon-ion irradiation was completely inhibited by pretreating cells with genistein and H7, indicating that Src tyrosine kinase and protein kinase C on cell surface membranes is involved in the induction. Carbon 30-36 vascular endothelial growth factor A Homo sapiens 17-21 10947125-11 2000 CONCLUSION: Irradiation of lung carcinoma cells with carbon ions induced VEGF mRNA expression and increased protein levels. Carbon 53-59 vascular endothelial growth factor A Homo sapiens 73-77 10905295-5 2000 Electroplating of aquated iridium complexes on the glassy carbon electrode resulted in the formation of the iridium oxide (IrOx) surface film, which was used in the heterogeneous detection system for insulin. Carbon 58-64 insulin Homo sapiens 200-207 10913600-7 2000 When Isa2p was depleted by regulated gene expression, mtDNA was maintained, but cells grew slowly on non-fermentable carbon sources. Carbon 117-123 Isa2p Saccharomyces cerevisiae S288C 5-10 10877846-9 2000 Ade16p was observed to be more abundant in cells grown on nonfermentable carbon sources than in glucose-grown cells, suggesting a role for this isozyme in respiration or sporulation. Carbon 73-79 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase ADE16 Saccharomyces cerevisiae S288C 0-6 10861956-1 2000 Chiral discrimination of racemic carbazole carbonyl (CC)-amino acids with linear alkyl sidechain (C(1)-C(4)) by bovine serum albumin (BSA) was investigated by competitive replacement experiments using dansyl-L-proline and dansyl-D-norvaline as fluorescent probes. Carbon 0-1 albumin Homo sapiens 119-132 10811893-15 2000 The fact that TPK2 mutants grow better than wild types on nonfermentable carbon sources and on media deficient in iron supports the unique role of Tpk2 in respiratory growth and carbon source use. Carbon 73-79 cAMP-dependent protein kinase catalytic subunit TPK2 Saccharomyces cerevisiae S288C 14-18 10891098-1 2000 Most ligands for the estrogen receptor (ER) are not well suited for synthesis by combinatorial means, because their construction involves a series of carbon-carbon bond forming reactions that are not uniformly high yielding. Carbon 150-156 estrogen receptor 1 Homo sapiens 21-38 10891098-1 2000 Most ligands for the estrogen receptor (ER) are not well suited for synthesis by combinatorial means, because their construction involves a series of carbon-carbon bond forming reactions that are not uniformly high yielding. Carbon 150-156 estrogen receptor 1 Homo sapiens 40-42 10891098-1 2000 Most ligands for the estrogen receptor (ER) are not well suited for synthesis by combinatorial means, because their construction involves a series of carbon-carbon bond forming reactions that are not uniformly high yielding. Carbon 157-163 estrogen receptor 1 Homo sapiens 21-38 10891098-1 2000 Most ligands for the estrogen receptor (ER) are not well suited for synthesis by combinatorial means, because their construction involves a series of carbon-carbon bond forming reactions that are not uniformly high yielding. Carbon 157-163 estrogen receptor 1 Homo sapiens 40-42 10777484-5 2000 In addition, NO was found to exert an inhibitory effect downstream of the TNFalpha-triggered ceramide accumulation, because NO donors reversed the inhibition of endocytosis induced by the cell-permeant C(2)-ceramide. Carbon 202-203 tumor necrosis factor Homo sapiens 74-82 18967999-1 2000 A differential pulse anodic stripping voltammetry was developed for the sensitive and selective determination of Co(II) at 2,4,6-tri(3,5-dimethylpyrazoyl)-1,3,5-triazine modified carbon paste electrode in 0.1 mol l(-1) NH(4)Cl solution (pH 4.95). Carbon 179-185 mitochondrially encoded cytochrome c oxidase II Homo sapiens 113-119 10889557-4 2000 We demonstrate that substitution of the C-36 residue causes a slight reduction of Sp1 and Sp3 binding, but this has no effect on transcription in vivo. Carbon 40-41 Sp3 transcription factor Homo sapiens 90-93 12212152-6 2000 Diastolic blood pressure(DBP) was positively correlated with age, body height, weight, IBM, FBS, blood TC and LDL-C, whereas it was negatively correlated with blood HDL-C/TC. Carbon 113-115 D-box binding PAR bZIP transcription factor Homo sapiens 25-28 10817690-7 2000 Clearance (CL) of gentamicin C(1), 4.62+/-0.71 ml min(-1) kg(-1), was significantly higher (P = 0.0156) than CL of gentamicin C(1a), 1.81+/-0.26 ml min(-1) kg(-1), and C(2), 1.82+/-0.25 ml min(-1) kg(-1). Carbon 0-1 CD59 molecule (CD59 blood group) Homo sapiens 50-56 10817690-7 2000 Clearance (CL) of gentamicin C(1), 4.62+/-0.71 ml min(-1) kg(-1), was significantly higher (P = 0.0156) than CL of gentamicin C(1a), 1.81+/-0.26 ml min(-1) kg(-1), and C(2), 1.82+/-0.25 ml min(-1) kg(-1). Carbon 0-1 CD59 molecule (CD59 blood group) Homo sapiens 148-154 10817690-7 2000 Clearance (CL) of gentamicin C(1), 4.62+/-0.71 ml min(-1) kg(-1), was significantly higher (P = 0.0156) than CL of gentamicin C(1a), 1.81+/-0.26 ml min(-1) kg(-1), and C(2), 1.82+/-0.25 ml min(-1) kg(-1). Carbon 0-1 CD59 molecule (CD59 blood group) Homo sapiens 148-154 10811893-15 2000 The fact that TPK2 mutants grow better than wild types on nonfermentable carbon sources and on media deficient in iron supports the unique role of Tpk2 in respiratory growth and carbon source use. Carbon 178-184 cAMP-dependent protein kinase catalytic subunit TPK2 Saccharomyces cerevisiae S288C 14-18 10821718-7 2000 The potency and selectivity shown by some of these ligands for the NET, serotonine transporter (SERT), or NET/SERT is striking, particularly in view of the displacement of the aromatic ring in this series from its usual position at C-3 in the WIN analogues. Carbon 232-233 solute carrier family 6 member 4 Rattus norvegicus 72-94 10821718-7 2000 The potency and selectivity shown by some of these ligands for the NET, serotonine transporter (SERT), or NET/SERT is striking, particularly in view of the displacement of the aromatic ring in this series from its usual position at C-3 in the WIN analogues. Carbon 232-233 solute carrier family 6 member 4 Rattus norvegicus 96-100 10821718-7 2000 The potency and selectivity shown by some of these ligands for the NET, serotonine transporter (SERT), or NET/SERT is striking, particularly in view of the displacement of the aromatic ring in this series from its usual position at C-3 in the WIN analogues. Carbon 232-233 solute carrier family 6 member 4 Rattus norvegicus 110-114 10794683-7 2000 GLP-1 could be derivatized with linear fatty acids up to the length of 16 carbon atoms, sometimes longer, almost anywhere in the C-terminal part without considerable loss of potency. Carbon 74-80 glucagon Homo sapiens 0-5 10769169-13 2000 c/dATP stimulated caspase-9 processing and downstreamcaspase activation were significantly suppressed in the presence ofTPCK and APF. Carbon 0-1 caspase 9 Rattus norvegicus 18-27 10733890-1 2000 Acyl-acyl carrier protein synthase (Aas) is widely used to synthesize thioester adducts of fatty acids between 8 and 18 carbons in length enzymatically to the phosphopantetheine group of acyl carrier protein. Carbon 120-127 FYVE, RhoGEF and PH domain containing 1 Homo sapiens 36-39 10777520-7 2000 When expressed in multicopy, the human construct rescued the growth of a yeast coq3 null mutant on a nonfermentable carbon source and restored coenzyme Q biosynthesis, although at lower levels than that of wild type yeast. Carbon 116-122 hexaprenyldihydroxybenzoate methyltransferase Saccharomyces cerevisiae S288C 79-83 10760476-3 2000 Medium chain FA with 12 or less carbons activated hexokinase in a chain length dependent manner with the greater activation shown by laurate. Carbon 32-39 hexokinase 1 Homo sapiens 50-60 10733890-1 2000 Acyl-acyl carrier protein synthase (Aas) is widely used to synthesize thioester adducts of fatty acids between 8 and 18 carbons in length enzymatically to the phosphopantetheine group of acyl carrier protein. Carbon 120-127 FYVE, RhoGEF and PH domain containing 1 Homo sapiens 0-34 10990626-1 2000 We show that these BOP"s allow the concept of single, double, triple, and conjugate bonds in carbon systems to be quantified, the average error compared to accurate tight-binding predictions being only 1% for the sigma bonds and 15% for the pi bonds. Carbon 93-99 BOP Homo sapiens 19-22 10771059-7 2000 CLGI material separated n-alcohols C(1) to C(8) based on the hydrophobic interaction between the protein material and the carbon chain of the alcohols. Carbon 122-128 TIMP metallopeptidase inhibitor 1 Homo sapiens 0-4 10727520-7 2000 The four-carbon side chained tyrphostins were much less potent; however, a very interesting pattern was observed in which removal of phenolic hydroxyls on the tyrphostin structure increased the potency for PDE1 and PDE3, but not PDE4. Carbon 9-15 phosphodiesterase 4A Homo sapiens 229-233 10785555-5 2000 Furthermore, for the effective inhibition of DNA topoisomerase I, the size of acyl moiety of 6-acylated derivatives seems to be limited to < 12 carbon atoms. Carbon 147-153 topoisomerase (DNA) I Mus musculus 45-64 10706635-6 2000 In the human QR1-duroquinone structure one ring carbon is significantly closer to the flavin N5, suggesting a direct hydride transfer to this atom. Carbon 48-54 NAD(P)H quinone dehydrogenase 1 Homo sapiens 13-16 10670838-3 2000 Circulating PMN were isolated during 12 days, followed by determination of formyl-methionyl-leucyl-phenylalanine (fMLP)-induced PMN-superoxide production (PMN-SOP) by SOD-inhibitable ferricytochrome C reduction, and PMN cytosolic Ca2+ concentration ([Ca2+]i) by fluorescent fura2/AM (340/380 ratio). Carbon 0-1 formyl peptide receptor 1 Homo sapiens 114-118 10646517-5 2000 We found that several proteins tyrosine-phosphorylated in response to BDNF showed enhanced levels of tyrosine phosphorylation in cultured neurons infected with C/S mutant adenovirus in comparison with those infected with the wild-type Shp-2 adenovirus. Carbon 160-161 protein tyrosine phosphatase, non-receptor type 11 Rattus norvegicus 235-240 10646517-7 2000 We found that the Shp-2-binding protein, brain immunoglobulin-like molecule with tyrosine-based activation motifs (BIT), was strongly tyrosine-phosphorylated in response to BDNF in cultured neurons expressing the C/S mutant of Shp-2. Carbon 213-214 protein tyrosine phosphatase, non-receptor type 11 Rattus norvegicus 18-23 10751038-10 2000 CONCLUSIONS: The structural requirements for valproylamide analogues for potent in vitro mEH inhibition are: an unsubstituted amide moiety; two saturated alkyl side chains; a minimum of eight carbons in the molecule. Carbon 192-199 epoxide hydrolase 1, microsomal Mus musculus 89-92 10757313-0 2000 WAF1 accumulation by carbon-ion beam and alpha-particle irradiation in human glioblastoma cultured cells. Carbon 21-27 cyclin dependent kinase inhibitor 1A Homo sapiens 0-4 10757313-2 2000 In the present study, it was examined whether WAF1 accumulation was induced after carbon-ion (C-) beam or alpha-particle irradiation in four glioblastoma cell lines. Carbon 82-88 cyclin dependent kinase inhibitor 1A Homo sapiens 46-50 16232852-5 2000 Methanol as an external carbon source was added during the anoxic phase to reduce nitrate nitrogen (NO3-) when denitrification was completed. Carbon 24-30 NBL1, DAN family BMP antagonist Homo sapiens 100-103 10620374-2 2000 In the present investigation we probed the vitamin D sterol-binding pocket of human DBP with affinity labeling analogs of 25-hydroxyvitamin D(3) ?25-OH-D(3) and 1, 25-dihydroxyvitamin D(3) ?1,25(OH)(2)D(3) containing bromoacetate alkylating probe at C-3 (A-ring), C-6 (triene), C-11 (C-ring), and C-19 (exocyclic methylene) of the parent sterol. Carbon 250-251 D-box binding PAR bZIP transcription factor Homo sapiens 84-87 10625697-4 2000 In contrast to rapidly proliferating cells, both Bcy1p and Tpk1p are distributed over nucleus and cytoplasm in cells growing on a nonfermentable carbon source or in stationary phase cells. Carbon 145-151 cAMP-dependent protein kinase catalytic subunit TPK1 Saccharomyces cerevisiae S288C 59-64 10679634-3 2000 Various saturated chain methylene CD(2) and carbon-carbon (C&bond;C) stretching mode peak height intensity ratios and line width parameters for the polycrystalline samples demonstrate a high degree of sn-1 chain order that is unaffected by either the double bond placement or number of unsaturated bonds within the sn-2 chain. Carbon 44-50 solute carrier family 38 member 3 Homo sapiens 205-209 10679634-3 2000 Various saturated chain methylene CD(2) and carbon-carbon (C&bond;C) stretching mode peak height intensity ratios and line width parameters for the polycrystalline samples demonstrate a high degree of sn-1 chain order that is unaffected by either the double bond placement or number of unsaturated bonds within the sn-2 chain. Carbon 51-57 solute carrier family 38 member 3 Homo sapiens 205-209 10679634-3 2000 Various saturated chain methylene CD(2) and carbon-carbon (C&bond;C) stretching mode peak height intensity ratios and line width parameters for the polycrystalline samples demonstrate a high degree of sn-1 chain order that is unaffected by either the double bond placement or number of unsaturated bonds within the sn-2 chain. Carbon 34-35 solute carrier family 38 member 3 Homo sapiens 205-209 10679634-5 2000 The lipid bilayer chain packing differences observed between the sn-1 and sn-2 chains of this series of monounsaturated and polyunsaturated 20 carbon chain lipids suggest the existence of laterally distributed microdomains predicated on the formation of highly ordered, saturated sn-1 chain clusters. Carbon 143-149 solute carrier family 38 member 3 Homo sapiens 65-69 10656581-0 2000 Carbon metabolism in developing soybean root nodules: the role of carbonic anhydrase. Carbon 0-6 carbonic anhydrase Glycine max 66-84 10661547-0 2000 Is the dominance of even carbon atom molecules odd? Carbon 25-31 odd-skipped related transcription factor 1 Homo sapiens 47-50 10661547-1 2000 The unexpected higher frequency of occurrence of even carbon atom molecules over odd carbon atom ones revealed through previous database searches is shown to be a consequence of the predominantly bimolecular nature of bond formation processes and the fact that combinations of odd and odd as well as even and even atom molecules result in even atom products whereas odd and even atom molecule combinations alone lead to odd atom products. Carbon 54-60 odd-skipped related transcription factor 1 Homo sapiens 81-84 10661547-1 2000 The unexpected higher frequency of occurrence of even carbon atom molecules over odd carbon atom ones revealed through previous database searches is shown to be a consequence of the predominantly bimolecular nature of bond formation processes and the fact that combinations of odd and odd as well as even and even atom molecules result in even atom products whereas odd and even atom molecule combinations alone lead to odd atom products. Carbon 54-60 odd-skipped related transcription factor 1 Homo sapiens 277-280 10661547-1 2000 The unexpected higher frequency of occurrence of even carbon atom molecules over odd carbon atom ones revealed through previous database searches is shown to be a consequence of the predominantly bimolecular nature of bond formation processes and the fact that combinations of odd and odd as well as even and even atom molecules result in even atom products whereas odd and even atom molecule combinations alone lead to odd atom products. Carbon 54-60 odd-skipped related transcription factor 1 Homo sapiens 277-280 10661547-1 2000 The unexpected higher frequency of occurrence of even carbon atom molecules over odd carbon atom ones revealed through previous database searches is shown to be a consequence of the predominantly bimolecular nature of bond formation processes and the fact that combinations of odd and odd as well as even and even atom molecules result in even atom products whereas odd and even atom molecule combinations alone lead to odd atom products. Carbon 54-60 odd-skipped related transcription factor 1 Homo sapiens 277-280 10661547-1 2000 The unexpected higher frequency of occurrence of even carbon atom molecules over odd carbon atom ones revealed through previous database searches is shown to be a consequence of the predominantly bimolecular nature of bond formation processes and the fact that combinations of odd and odd as well as even and even atom molecules result in even atom products whereas odd and even atom molecule combinations alone lead to odd atom products. Carbon 54-60 odd-skipped related transcription factor 1 Homo sapiens 277-280 10661547-1 2000 The unexpected higher frequency of occurrence of even carbon atom molecules over odd carbon atom ones revealed through previous database searches is shown to be a consequence of the predominantly bimolecular nature of bond formation processes and the fact that combinations of odd and odd as well as even and even atom molecules result in even atom products whereas odd and even atom molecule combinations alone lead to odd atom products. Carbon 85-91 odd-skipped related transcription factor 1 Homo sapiens 81-84 16118870-0 1999 Oxidative cleavage of vic-diols to aldehydes with dioxygen catalyzed by Ru(PPh3)3Cl2 on active carbon. Carbon 95-101 caveolin 1 Homo sapiens 75-79 10604478-7 1999 TOR inhibits expression of carbon-source-regulated genes by stimulating the binding of the transcriptional activators MSN2 and MSN4 to the cytoplasmic 14-3-3 protein BMH2. Carbon 27-33 stress-responsive transcriptional activator MSN4 Saccharomyces cerevisiae S288C 127-131 10536147-0 1999 Expression of GUT1, which encodes glycerol kinase in Saccharomyces cerevisiae, is controlled by the positive regulators Adr1p, Ino2p and Ino4p and the negative regulator Opi1p in a carbon source-dependent fashion. Carbon 181-187 glycerol kinase Saccharomyces cerevisiae S288C 14-18 10536147-2 1999 The carbon source regulation of GUT1 was studied using promoter-reporter gene fusions. Carbon 4-10 glycerol kinase Saccharomyces cerevisiae S288C 32-36 10536147-8 1999 Together, the experiments show that GUT1 is carbon source regulated by different activation and repression systems. Carbon 44-50 glycerol kinase Saccharomyces cerevisiae S288C 36-40 10504238-11 1999 A 14% increase in the isotropic hyperfine coupling of the remote dimethylbenzimidazole (14)N nucleus in enzyme-bound versus free base-on cob(II)alamin shows an enhanced delocalization of unpaired spin density from Co(II) onto the axial ligand, which would contribute to the acceleration of the cobalt-carbon bond cleavage rate in situ. Carbon 301-307 mitochondrially encoded cytochrome c oxidase II Homo sapiens 214-220 10487929-1 1999 While using YIp356 and YEp356R lacZ reporter plasmids, we found lacZ expression driven by the ARG2 promoter to be much higher in cells grown on a non-glucose carbon source than in glucose-grown cells (5-10-fold higher on galactose and up to 40-fold higher on ethanol). Carbon 158-164 acetyl-CoA:L-glutamate N-acetyltransferase Saccharomyces cerevisiae S288C 94-98 10718282-6 2000 RESULTS: In CR1-A and CR1-B dyslipoproteinemia was found at different stages of renal insufficiency which was manifested by the significant increase of TG, TC, LDL-C, apo B levels and TC/HDL-C, LDL-C/HDL-C ratios and significant decrease of HDL-C level and apo AI/apoB, HDL-C/apoAI ratios in comparison with controls. Carbon 12-13 apolipoprotein A1 Homo sapiens 241-263 10718282-6 2000 RESULTS: In CR1-A and CR1-B dyslipoproteinemia was found at different stages of renal insufficiency which was manifested by the significant increase of TG, TC, LDL-C, apo B levels and TC/HDL-C, LDL-C/HDL-C ratios and significant decrease of HDL-C level and apo AI/apoB, HDL-C/apoAI ratios in comparison with controls. Carbon 12-13 apolipoprotein B Homo sapiens 264-268 10601259-3 1999 The alpha-carbon of the conserved lysine present near the C-terminal end of the transmembrane helix (Lys(1125) in alpha2, Lys(1022) in alpha5, Lys(752) in beta1, and Lys(724) in beta2) is buried in the plasma membrane, and the charged amino group most likely reaches into the polar head-group region of the lipid bilayer. Carbon 10-16 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 155-160 10588903-5 1999 According to quantitative analysis with folded Gaussian distributions, the bending induced by p53 varied from approximately 40 degrees to 48 degrees upon decreasing of the KCl concentration from 50 mM to approximately 1 mM in the mounting buffer used for adsorption of the complexes to the carbon film surface. Carbon 290-296 tumor protein p53 Homo sapiens 94-97 16118870-1 1999 [reaction: see text] A variety of vic-diols were first successfully cleaved to the corresponding aldehydes with dioxygen catalyzed by Ru(PPh3)3Cl2 on active carbon in fair to good yields. Carbon 157-163 caveolin 1 Homo sapiens 137-141 10484460-1 1999 Increased phospholipase A2 (PLA2) activity was measured in cytosolic fractions of lungs from sheep exposed to smoke from burning cotton or to synthetic smoke consisting of carbon and acrolein, a cotton smoke toxin. Carbon 172-178 phospholipase A2 Ovis aries 10-26 10484460-1 1999 Increased phospholipase A2 (PLA2) activity was measured in cytosolic fractions of lungs from sheep exposed to smoke from burning cotton or to synthetic smoke consisting of carbon and acrolein, a cotton smoke toxin. Carbon 172-178 phospholipase A2 Ovis aries 28-32 10589376-7 1999 It is speculated that decreased anaplerotic carbon flux in the tricarboxylic acid cycle, as a consequence of insulin resistance, may have an important role in the down-regulation of transamination of leucine during pregnancy, and may contribute to the conservation and accretion of nitrogen by the mother and the fetus. Carbon 44-50 insulin Homo sapiens 109-116 10364640-9 1999 Thus, not only MTHFR but also APOE appears to be related to the one-carbon metabolism, suggesting that APOE4 and insufficient one-carbon metabolism may be synergistic risk factors for AD. Carbon 68-74 apolipoprotein E Homo sapiens 30-34 10482686-4 1999 In contrast, the modest induction of mRNA for cytosolic GS1 by light is primarily mediated by changes in the levels of carbon metabolites. Carbon 119-125 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein Arabidopsis thaliana 56-59 10452956-8 1999 Moreover, expression of UGP1 allows a gal7 strain to grow on galactose as a sole carbon source. Carbon 81-87 UDP-glucose pyrophosphorylase 2 Homo sapiens 24-28 10452956-8 1999 Moreover, expression of UGP1 allows a gal7 strain to grow on galactose as a sole carbon source. Carbon 81-87 galectin 7B Homo sapiens 38-42 10383954-4 1999 The PAO1 rpoS mutant was slightly more sensitive to carbon starvation than the wild-type strain, but this phenotype was obvious only when the cells were grown in a medium supplemented with glucose as the sole carbon source. Carbon 52-58 RNA polymerase sigma factor RpoS Pseudomonas aeruginosa PAO1 9-13 10383954-4 1999 The PAO1 rpoS mutant was slightly more sensitive to carbon starvation than the wild-type strain, but this phenotype was obvious only when the cells were grown in a medium supplemented with glucose as the sole carbon source. Carbon 209-215 RNA polymerase sigma factor RpoS Pseudomonas aeruginosa PAO1 9-13 10398348-3 1999 After expression in S. cerevisiae from an S. cerevisiae promoter, it was shown to functionally complement an S. cerevisiae idh1 mutant, but not an idh2 mutant, for growth on acetate as a carbon source and for production of NAD(+)-isocitrate dehydrogenase enzyme activity. Carbon 187-193 isocitrate dehydrogenase (NAD(+)) IDH1 Saccharomyces cerevisiae S288C 123-127 10529000-3 1999 Placement of the phenolic hydroxyl group on the various carbons of the aromatic A-ring of estratrien-17betaol (carbons 1-3) produced ligands which diminished the steady state level of ERalpha mRNA in relation to their affinity for receptor. Carbon 56-63 estrogen receptor 1 Homo sapiens 184-191 10529000-3 1999 Placement of the phenolic hydroxyl group on the various carbons of the aromatic A-ring of estratrien-17betaol (carbons 1-3) produced ligands which diminished the steady state level of ERalpha mRNA in relation to their affinity for receptor. Carbon 111-118 estrogen receptor 1 Homo sapiens 184-191 10529000-5 1999 Although this A-ring isomer brought about apparent processing of the nuclear receptor, the ERalpha reappeared in the cytosol within 24 h. Unlike the stimulation of genes regulated via estrogen response elements, maximum autologous negative regulation of the ERalpha gene required the presence of an hydroxyl group on carbon 17 of the D-ring. Carbon 317-323 estrogen receptor 1 Homo sapiens 91-98 10529000-5 1999 Although this A-ring isomer brought about apparent processing of the nuclear receptor, the ERalpha reappeared in the cytosol within 24 h. Unlike the stimulation of genes regulated via estrogen response elements, maximum autologous negative regulation of the ERalpha gene required the presence of an hydroxyl group on carbon 17 of the D-ring. Carbon 317-323 estrogen receptor 1 Homo sapiens 258-265 10411744-3 1999 Among 52 proteins induced by a shift from 25 degrees C to 38 degrees C, half of them were found to be dependent upon Msn2p and/or Msn4p (including mostly antioxidants and enzymes involved in carbon metabolism), while the other half (including mostly chaperones and associated proteins) were dependent upon Hsf1p. Carbon 191-197 stress-responsive transcriptional activator MSN4 Saccharomyces cerevisiae S288C 130-135 10359799-12 1999 Finally, we find that gcn5 and rpd3 single mutants are not defective in meiosis if acetate is absent and respiration is promoted by a metabolically unrelated carbon source. Carbon 158-164 histone deacetylase RPD3 Saccharomyces cerevisiae S288C 31-35 10373490-2 1999 Fen2p was postulated to act as a common regulator of carbon and nitrogen catabolite repression and of amino acid and ergosterol biosynthesis. Carbon 53-59 Fen2p Saccharomyces cerevisiae S288C 0-5 10036770-3 1999 The production of the insulin fusion proteins were carried out in high-cell density fed-batch cultures using a synthetic medium with glucose as sole carbon and energy source. Carbon 149-155 insulin Homo sapiens 22-29 10421035-6 1999 Carbon isotope fractionation across the lung was approximately 30% lower than predicted from the fractionation factor between bicarbonates and gaseous CO2 (1.00674 at 37 degrees C, or a approximately 6.6% delta 13C PDB-1 difference). Carbon 0-6 PDB1 Homo sapiens 215-220 10103055-2 1999 Yeast mutants defective in the ACN9 gene display phenotypes identical with mutants defective in metabolic enzymes required for carbon assimilation. Carbon 127-133 Sdh7p Saccharomyces cerevisiae S288C 31-35 10219994-0 1999 Regulation of the expression of the Kluyveromyces lactis PDC1 gene: carbon source-responsive elements and autoregulation. Carbon 68-74 indolepyruvate decarboxylase 1 Saccharomyces cerevisiae S288C 57-61 10064623-0 1999 The Ice Man"s diet as reflected by the stable nitrogen and carbon isotopic composition of his hair. Carbon 59-65 carboxylesterase 2 Homo sapiens 4-7 10064623-5 1999 Here we report that the stable carbon and nitrogen isotope values for the hair of the 5200 year-old Ice Man indicates a primarily vegetarian diet, in agreement with his dental wear pattern. Carbon 31-37 carboxylesterase 2 Homo sapiens 100-103 9895279-9 1999 An analogue with a ring attached via a four-carbon chain, which included an amide linkage and a hydroxy group on the alpha-carbon atom, inhibited competitively (Ki=62.0 microM), suggesting that it may be possible to design bisphosphonate inhibitors which contain a photoactivatable azido group for photoaffinity labelling of V-PPase active site. Carbon 44-50 inorganic pyrophosphatase 1 Homo sapiens 327-332 9895279-9 1999 An analogue with a ring attached via a four-carbon chain, which included an amide linkage and a hydroxy group on the alpha-carbon atom, inhibited competitively (Ki=62.0 microM), suggesting that it may be possible to design bisphosphonate inhibitors which contain a photoactivatable azido group for photoaffinity labelling of V-PPase active site. Carbon 123-129 inorganic pyrophosphatase 1 Homo sapiens 327-332 10730193-1 1999 The B12 or cobalamin coenzymes are complex macrocycles whose reactivity is associated with a unique cobalt-carbon bond. Carbon 107-113 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 4-7 11068827-3 1999 Under solar radiation (116 MJ m(-2)), 17-21% of the 14C-labelled carbons in DHP and 18-23% of the indigenous DOC were mineralized in 7 d. Simultaneously the water solubility of 14C-DHP increased. Carbon 65-72 dihydropyrimidinase Homo sapiens 76-79 9850065-13 1998 Incubations of NNK with COX-1 and -2 produced both activation and detoxification products by alpha-carbon hydroxylation and N-oxydation pathways, respectively. Carbon 99-105 cytochrome c oxidase I, mitochondrial Mus musculus 24-36 10574612-1 1999 The release of basic fibroblast growth factor (bFGF) and platelet derived growth factor AB (PDGF-AB) by in vitro cultured human umbilical endothelial cells in contact with carbon and collagen coated polyethylene terephthalate (PET + PC) was assessed by enzyme immunoassay. Carbon 172-178 fibroblast growth factor 2 Homo sapiens 15-45 10574612-1 1999 The release of basic fibroblast growth factor (bFGF) and platelet derived growth factor AB (PDGF-AB) by in vitro cultured human umbilical endothelial cells in contact with carbon and collagen coated polyethylene terephthalate (PET + PC) was assessed by enzyme immunoassay. Carbon 172-178 fibroblast growth factor 2 Homo sapiens 47-51 9869601-6 1999 RESULTS: Plasma CCK concentration was consistently and similarly elevated by fatty acids with a chain of 12 carbon atoms or longer, whereas those of 11 or fewer carbon atoms failed to increase plasma CCK. Carbon 108-114 cholecystokinin Homo sapiens 16-19 16232563-1 1999 Corn starch and soybean oil are suitable carbon sources for the production of tetracycline by Streptomyces aureofacience CG-1. Carbon 41-47 beta-conglycinin alpha' subunit Glycine max 121-125 9851993-8 1998 In an environment with 1,2-propanediol as the sole carbon and energy source, expression of the prpBCDE operon is ensured by the Pdu protein that has CobB-like activity. Carbon 51-57 NAD-dependent protein deacylase Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 149-153 9843506-0 1998 Sip4, a Snf1 kinase-dependent transcriptional activator, binds to the carbon source-responsive element of gluconeogenic genes. Carbon 70-76 Sip4p Saccharomyces cerevisiae S288C 0-4 9739146-5 1998 The mRNA level of the AE3 Cl-/HCO3- exchanger was increased by ammonia in a calphostin C- and H-7-sensitive manner. Carbon 26-27 solute carrier family 4 member 3 Homo sapiens 22-25 9845343-2 1998 Cyc2p from Saccharomyces cerevisiae is a mitochondrial protein and that cyc2 mutants contained only approximately 20% of the normal levels of cytochrome c due to a partial deficiency in mitochondrial import of apo-cytochrome c. We report herein that deletion of the entire gene results in defective mitochondrial function, as revealed by diminished growth on media containing nonfermentable carbon sources. Carbon 391-397 oxidoreductase Saccharomyces cerevisiae S288C 0-5 9845343-2 1998 Cyc2p from Saccharomyces cerevisiae is a mitochondrial protein and that cyc2 mutants contained only approximately 20% of the normal levels of cytochrome c due to a partial deficiency in mitochondrial import of apo-cytochrome c. We report herein that deletion of the entire gene results in defective mitochondrial function, as revealed by diminished growth on media containing nonfermentable carbon sources. Carbon 391-397 oxidoreductase Saccharomyces cerevisiae S288C 72-76 9814455-11 1998 Similar results were obtained with the set point of C-PTH and of the C-PTH/I-PTH ratio. Carbon 52-53 parathyroid hormone Homo sapiens 54-57 9881155-8 1998 Moreover, the levels of ASN2 and ASN1 mRNA are also reciprocally regulated by carbon and nitrogen metabolites. Carbon 78-84 glutamine-dependent asparagine synthase 1 Arabidopsis thaliana 33-37 9811645-2 1998 The DAS1 gene, encoding DHAS, was cloned from the host genome, and regulation of its expression by various carbon and nitrogen sources was analyzed. Carbon 107-113 SCF ubiquitin ligase complex subunit DAS1 Saccharomyces cerevisiae S288C 4-8 9811645-5 1998 The DAS1 gene was disrupted in one step in the host genome (das1Delta strain), and the growth of the das1Delta strain in various carbon and nitrogen sources was compared with that of the wild-type strain. Carbon 129-135 SCF ubiquitin ligase complex subunit DAS1 Saccharomyces cerevisiae S288C 4-8 9765282-7 1998 Cleavage of the C-propeptide occurs efficiently in recombinant pro-alpha1(V) homotrimers produced in 293-EBNA human embryonic kidney cells, and this cleavage is shown to occur immediately downstream of the sequence RTRR. Carbon 0-1 collagen type V alpha 1 chain Homo sapiens 63-76 9871930-8 1998 Cardiac output values in L.min-1 (mean +/- SD) were as follows: C, 4.99 +/- 0.39; FiO2, 5.44 +/- 0.86; FiIG, 5.55 +/- 0.92; TH, 5.77 +/- 0.88; and E, 5.53 +/- 0.64. Carbon 0-1 CD59 molecule (CD59 blood group) Homo sapiens 27-32 29710957-0 1998 An Efficient Nickel-Catalyzed Cross-Coupling Between sp3 Carbon Centers. Carbon 57-63 Sp3 transcription factor Homo sapiens 53-56 29710957-1 1998 Since the pioneering work of Wurtz, cross-couplings between sp3 carbon centers have had the reputation of being difficult. Carbon 64-70 Sp3 transcription factor Homo sapiens 60-63 29710957-2 1998 In the presence of a catalytic amount of m-trifluoromethylstyrene, an efficient cross-coupling reaction takes place between polyfunctional primary alkyl iodides and diorganozinc compounds [Eq. (a)] to give a general catalytic cross-coupling between sp3 carbon centers. Carbon 253-259 Sp3 transcription factor Homo sapiens 249-252 9801832-3 1998 As to the catalytic mechanism of CPA, it is generally believed that while in the cases of ester substrates the carboxylate of Glu-270 functions as the nucleophile which attacks the scissile carbonyl carbon (anhydride pathway), in the case of peptide substrates the zinc-bound water molecule attacks the scissile peptide bond (general base pathway). Carbon 190-196 carboxypeptidase A1 Homo sapiens 33-36 9724521-9 1998 The structures of both thrombin and trypsin complexes show similar well-defined transition states in the S1 site and at the electrophilic carbon atom and Ser195OG. Carbon 138-144 coagulation factor II, thrombin Homo sapiens 23-31 9726966-5 1998 Deletion of either the ARP9 or ARP7 gene causes typical swi/snf phenotypes, including growth defects on media containing galactose, glycerol, or sucrose as sole carbon sources. Carbon 161-167 Arp9p Saccharomyces cerevisiae S288C 23-27 9801832-8 1998 We have also demonstrated that N-(hydroxyacetyl)-L-phenylalanine (L-2) inactivates the enzyme with the kinact/KI value of 0.071 M-1 s-1, suggesting that the carboxylate becomes to attack the peptide carbonyl carbon to generate the same anhydride intermediate as that formed in the inactivation of CPA by L-1. Carbon 199-205 carboxypeptidase A1 Homo sapiens 297-300 9733534-2 1998 Here we show that the circadian rhythm controlling the activity of sucrose phosphate synthase (SPS) and nitrate reductase (NR), key control points of carbon and nitrogen metabolism in plant cells, is delayed in tomato by chilling treatments. Carbon 151-157 nitrate reductase [NADH] Solanum lycopersicum 105-122 9733534-2 1998 Here we show that the circadian rhythm controlling the activity of sucrose phosphate synthase (SPS) and nitrate reductase (NR), key control points of carbon and nitrogen metabolism in plant cells, is delayed in tomato by chilling treatments. Carbon 151-157 nitrate reductase [NADH] Solanum lycopersicum 124-126 9482718-5 1998 Complementation of the high inorganic carbon concentration-requiring mutant, cia-3, with a subcloned cosmid containing the cah3 gene yielded transformants that grew on atmospheric levels of CO2 (0.035%) and contained an active 29.5 kDa alpha-type carbonic anhydrase. Carbon 38-44 uncharacterized protein Chlamydomonas reinhardtii 123-127 9733985-1 1998 We have determined calorimetrically the phase transition temperature (Tm) values of five sn-1 saturated/sn-2 unsaturated phosphatidylethanolamines (PE) in which the sn-1 acyl chain has 20 carbons and the sn-2 acyl chain has 18 carbons with different number and position of the cis double bond. Carbon 188-195 solute carrier family 38 member 3 Homo sapiens 89-93 9733985-1 1998 We have determined calorimetrically the phase transition temperature (Tm) values of five sn-1 saturated/sn-2 unsaturated phosphatidylethanolamines (PE) in which the sn-1 acyl chain has 20 carbons and the sn-2 acyl chain has 18 carbons with different number and position of the cis double bond. Carbon 227-234 solute carrier family 38 member 3 Homo sapiens 89-93 9754931-6 1998 The antiproliferative action of these analogues was associated with profound shape change in neuro-2A neuroblastoma involving extensive neuritogenesis and an associated increase in neural cell adhesion molecule (NCAM) prevalence at points of cell-cell contact, the latter exhibiting a dose-dependent increase when the n-alkyl chain was extended to five carbon units. Carbon 353-359 neural cell adhesion molecule 1 Mus musculus 212-216 9638521-8 1998 IL-4-induced FBGC density was strongly influenced by the surface carbon content, as determined by X-ray photoelectron spectroscopy (XPS). Carbon 65-71 interleukin 4 Homo sapiens 0-4 11670507-1 1998 The rate constant of the self-decomposition of O(2)NOO(-) was determined to be 1.35 +/- 0.03 s(-)(1) at 25 degrees C. The decomposition rate constant of O(2)NOO(-) in the presence of C(NO(2))(4), CuSO(4), SOD, and Fe(CN)(6)(4)(-) was found to be 2.4 +/- 0.2 s(-)(1), independent of the concentration of these substrates. Carbon 115-116 superoxide dismutase 1 Homo sapiens 205-208 9687505-4 1998 We find that Cln3 protein levels are highest in glucose and lower in poorer carbon sources. Carbon 76-82 cyclin CLN3 Saccharomyces cerevisiae S288C 13-17 9689927-12 1998 These results document the amplification at the site of a putative HSR in an L1210 cell variant of the RFC-1 gene regulating expression of the one-carbon, reduced folate transporter. Carbon 147-153 replication factor C (activator 1) 1 Mus musculus 103-108 9711846-3 1998 Simultaneous disruption of the FRDS and OSM1 genes resulted in the inability of the yeasts to grow anaerobically on glucose as a carbon source, and disruption of the OSM1 gene caused poor growth under anaerobic conditions. Carbon 129-135 fumarate reductase Saccharomyces cerevisiae S288C 40-44 9638533-0 1998 Modification of glassy carbon surfaces with synthetic laminin-derived peptides for nerve cell attachment and neurite growth. Carbon 23-29 laminin, beta 2 (laminin S) Gallus gallus 54-61 9687977-0 1998 Cytotoxic effect of accelerated carbon beams on glioblastoma cell lines with p53 mutation: clonogenic survival and cell-cycle analysis. Carbon 32-38 tumor protein p53 Homo sapiens 77-80 9650266-1 1998 The characteristics of microbial growth and kinetics of DBP biodegradation was studied in a continuous culture system using DBP as a sole source of carbon. Carbon 148-154 D-box binding PAR bZIP transcription factor Homo sapiens 56-59 9634475-8 1998 In particular, a GATA/c-Ets motive was identified in a short segment homologous to the mouse CD4 distal enhancer, suggesting that LAG-3, which is embedded in the CD4 locus, may be controlled by some CD4 regulatory elements. Carbon 8-9 lymphocyte-activation gene 3 Mus musculus 130-135 11091657-4 1998 The relative biological effectiveness (RBE) of the carbon beam and X-ray irradiation was determined at the level of D10 (10% survival dose) on the dose-survival curve. Carbon 51-57 CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion Homo sapiens 116-119 9687977-1 1998 PURPOSE: The cytotoxic effect of high-LET carbon beams was analysed on p53 mutant and wild-type glioblastoma cell lines. Carbon 42-48 tumor protein p53 Homo sapiens 71-74 9641632-5 1998 ESCA survey spectra of samples coated with 1 microg/mL of fibronectin showed an increase in organic nitrogen and carbon compared with uncoated controls. Carbon 113-119 fibronectin 1 Homo sapiens 58-69 9687977-7 1998 Although p53 mutants were more resistant than wild-types for all radiation qualities, carbon beams yielded a higher RBE in p53 mutants than in wild-types. Carbon 86-92 tumor protein p53 Homo sapiens 123-126 9687977-9 1998 A G1 block was noticed after irradiation with gamma-rays and carbon beams of 20 and 40keV/microm in p53 wild-types. Carbon 61-67 tumor protein p53 Homo sapiens 100-103 9687977-11 1998 CONCLUSION: Accelerated carbon beams can yield higher RBE in gamma-resistant glioblastoma cell lines with p53 mutations. Carbon 24-30 tumor protein p53 Homo sapiens 106-109 9662534-4 1998 Lipid fatty acid profiles indicated that gly1 mutants exhibited a reduced carbon flux through the prokaryotic pathway that was compensated for by an increased carbon flux through the eukaryotic pathway. Carbon 74-80 NAD-dependent glycerol-3-phosphate dehydrogenase family protein Arabidopsis thaliana 41-45 9662534-4 1998 Lipid fatty acid profiles indicated that gly1 mutants exhibited a reduced carbon flux through the prokaryotic pathway that was compensated for by an increased carbon flux through the eukaryotic pathway. Carbon 159-165 NAD-dependent glycerol-3-phosphate dehydrogenase family protein Arabidopsis thaliana 41-45 9548924-4 1998 The generalized order parameters for methine carbons in the MAf are significantly lower for the deoxyribose bearing the damaged thymidine base and for the bases flanking the lesion on the undamaged strand, indicating additional conformational flexibility due to the lesion. Carbon 45-52 MAF bZIP transcription factor Homo sapiens 60-63 9729766-6 1998 Biochemical and physiological characterization of carbon metabolic mutants, along with the analysis of cloned genes and their corresponding gene products, have greatly advanced our understanding of the function of enzymes such as citrate synthase, oxoglutarate dehydrogenase, pyruvate carboxylase and malic enzymes. Carbon 50-56 pyruvate carboxylase Homo sapiens 276-296 9642094-8 1998 The modelled Thr1 side-chain is located above the gamma-turn bulge such that addition of its nucleophilic hydroxyl group to the electrophilic Gly-1 carbonyl carbon atom may proceed by very small motions. Carbon 148-154 threonine aldolase GLY1 Saccharomyces cerevisiae S288C 142-147 9642094-10 1998 The same structure also supports addition of the Thr1 hydroxyl group to the carbonyl carbon atom of Leu-2 as a model for the first step in substrate hydrolysis by the proteasome. Carbon 76-82 3-isopropylmalate dehydrogenase Saccharomyces cerevisiae S288C 100-105 9657379-3 1998 Here we report that the lack of I- transport activity in T354P NIS generated by site-directed mutagenesis, is not due to a structural change induced by proline, but rather to the absence of a hydroxyl group at the beta-carbon of the amino acid residue at position 354. Carbon 219-225 solute carrier family 5 member 5 Homo sapiens 63-66 9557171-5 1998 The time-weighted average intensity of exposure to CS2 vapor was measured using personal diffusive samplers (in which carbon cloth served as an adsorbent). Carbon 118-124 chorionic somatomammotropin hormone 2 Homo sapiens 51-54 10076532-8 1998 These results indicate that the rat CYP3A subfamily is capable of catalyzing C-8 hydroxylation of caffeine as is the case for human CYP3A4. Carbon 36-37 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 132-138 29711152-2 1998 In contrast, in analogous enediynes without an annelated cyclohexane ring a change in the hybridization of the bridging carbon atom from sp2 to sp3 leads to a dramatic increase in the cyclization rate. Carbon 120-126 Sp2 transcription factor Homo sapiens 137-140 9539701-1 1998 This review focuses on the monoterpene, sesquiterpene, and diterpene synthases of plant origin that use the corresponding C10, C15, and C20 prenyl diphosphates as substrates to generate the enormous diversity of carbon skeletons characteristic of the terpenoid family of natural products. Carbon 212-218 homeobox C10 Homo sapiens 122-125 9579445-5 1998 CONCLUSIONS: Low dosages of either dl-norgestrel (C-19) or medroxyprogesterone acetate (C-21) when combined with conjugated estrogen significantly improve plasma lipoprotein lipids of postmenopausal women. Carbon 0-1 TBL1X/Y related 1 Homo sapiens 88-92 9613820-2 1998 Derivatives of neuraminic acid occur widely, substituted in the amino and hydroxy side chains, as well in the C-9 carbon skeleton. Carbon 114-120 complement C9 Bos taurus 110-113 9526565-1 1998 Three previously unreported (R,S)-2,4-diamino-5-[(3,4,5-trimethoxyphenyl) alkyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidines 15a-c were synthesized as analogues of trimethoprim (TMP) and were tested as inhibitors of Pneumocystis carinii, Toxoplasma gondii, and rat liver dihydrofolate reductase (DHFR). Carbon 96-97 dihydrofolate reductase Rattus norvegicus 267-290 9526565-1 1998 Three previously unreported (R,S)-2,4-diamino-5-[(3,4,5-trimethoxyphenyl) alkyl]-6,7-dihydro-5H-cyclopenta[d]pyrimidines 15a-c were synthesized as analogues of trimethoprim (TMP) and were tested as inhibitors of Pneumocystis carinii, Toxoplasma gondii, and rat liver dihydrofolate reductase (DHFR). Carbon 96-97 dihydrofolate reductase Rattus norvegicus 292-296 9871590-2 1998 It was revealed that the methyl group at the three carbon bridge of (-)-huperzine A can form a weak hydrogen bond with the phenol hydroxyl oxygen of Tyr121 and the main-chain oxygen of Gly118 of AChE, respectively. Carbon 51-57 acetylcholinesterase (Cartwright blood group) Homo sapiens 195-199 29711152-2 1998 In contrast, in analogous enediynes without an annelated cyclohexane ring a change in the hybridization of the bridging carbon atom from sp2 to sp3 leads to a dramatic increase in the cyclization rate. Carbon 120-126 Sp3 transcription factor Homo sapiens 144-147 9858984-4 1998 The highest activity of catalase in the cultural fluid is seen on the nutrient medium containing 4% of carbon source. Carbon 103-109 catalase Homo sapiens 24-32 9568739-5 1998 The HCD+3, HCD+10, HCD+30 and CSTY lowered plasma TC (25, 32, 34 and 32%, respectively), VLDL-C (62, 74, 71 and 75%, respectively), LDL-C (25, 38, 47 and 46%, respectively) and TG (48, 47, 42 and 45%, respectively). Carbon 5-6 component of oligomeric golgi complex 2 Homo sapiens 90-95 10328542-1 1998 The cytotoxic effect of high-linear-energy transfer (LET) carbon beams on two human glioblastoma cell lines (A172 and TK1) was analyzed, especially concerning cell death, including apoptosis. Carbon 58-64 thymidine kinase 1 Homo sapiens 118-121 10328542-5 1998 The maximum values of the cell death index (CDI) were 50.2% in A172 and 37.5% in TK1, both obtained on day 7 after exposure to carbon beams of 80 keV/microm. Carbon 127-133 thymidine kinase 1 Homo sapiens 81-84 10328542-6 1998 Apoptosis was observed only on days 4 and 7 after carbon beam irradiation, with maximum values of 7% in A172 and 4.5% in TK1, and the induction of apoptosis after high-LET radiation could be p53-independent. Carbon 50-56 thymidine kinase 1 Homo sapiens 121-124 10681829-5 1998 As compared to ApoE3 allele, ApoE4 allele had positive effect on plasma TC, LDL-C and ApoB100 levels; while ApoE2 allele had negative effect on plasma TC, LDL-C and ApoB100 levels. Carbon 79-81 apolipoprotein E Homo sapiens 29-34 9696993-7 1998 After consumption of a protein-containing meal, BCAA and glutamate are taken up by muscle and their carbon skeletons are used for de novo synthesis of glutamine. Carbon 100-106 AT-rich interaction domain 4B Homo sapiens 48-52 9516034-1 1998 OBJECTIVE: Urinary 6beta-hydroxycortisol/cortisol (6beta-OHF/C) ratio was measured in human neonates to assess the CYP3A enzyme activity. Carbon 4-5 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 115-120 9399021-10 1997 In contrast the same insulin concentration inhibited C-7 binding of B- and T-lymphocytes by 35%. Carbon 53-54 insulin Homo sapiens 21-28 9398185-13 1997 A low-barrier hydrogen bond from PGH NOH to Glu-165 suggests a dual role for Glu-165 in catalysis of proton transfer not only between the C1 and C2 carbons but also between the O1 and O2 oxygens in the interconversion of DHAP and GAP in wild type TIM. Carbon 148-155 triosephosphate isomerase 1 Homo sapiens 247-250 9353282-13 1997 Expression of an Arabidopsis thaliana FAH1 gene, which does not contain the cytochrome b5 domain, in the fah1Delta strain produced an approximately 25-fold increase in alpha-HO 26:0 and reduced the levels of its 26-carbon precursor, suggesting that it functions in very long chain fatty acid hydroxylation using an alternate electron transfer mechanism. Carbon 215-221 fatty acid alpha-hydroxylase Saccharomyces cerevisiae S288C 38-42 9397406-4 1997 In contrast, the other major fatty-acid binding protein in liver, fatty-acid binding protein (L-FABP), displayed a much narrower carbon chain preference in general: polyunsaturated fatty acids > branched-chain phytol-derived fatty acids > 14- and 16-carbon saturated > branched-chain isoprenoids. Carbon 129-135 fatty acid binding protein 1 Homo sapiens 59-92 9397406-4 1997 In contrast, the other major fatty-acid binding protein in liver, fatty-acid binding protein (L-FABP), displayed a much narrower carbon chain preference in general: polyunsaturated fatty acids > branched-chain phytol-derived fatty acids > 14- and 16-carbon saturated > branched-chain isoprenoids. Carbon 129-135 fatty acid binding protein 1 Homo sapiens 94-100 9397406-4 1997 In contrast, the other major fatty-acid binding protein in liver, fatty-acid binding protein (L-FABP), displayed a much narrower carbon chain preference in general: polyunsaturated fatty acids > branched-chain phytol-derived fatty acids > 14- and 16-carbon saturated > branched-chain isoprenoids. Carbon 256-262 fatty acid binding protein 1 Homo sapiens 59-92 9397406-4 1997 In contrast, the other major fatty-acid binding protein in liver, fatty-acid binding protein (L-FABP), displayed a much narrower carbon chain preference in general: polyunsaturated fatty acids > branched-chain phytol-derived fatty acids > 14- and 16-carbon saturated > branched-chain isoprenoids. Carbon 256-262 fatty acid binding protein 1 Homo sapiens 94-100 23105179-5 1998 The levels of antioxidants i.e., superoxide dismutase (SOD) and catalase were found to decrease with the increase in exposure to carbon in industrial workers. Carbon 129-135 catalase Homo sapiens 64-72 9477574-8 1998 Whereas the TPT gene is predominantly present in tissues that perform photosynthetic carbon metabolism and the PPT gene appears to be ubiquitously expressed, the expression of the GPT gene is mainly restricted to heterotrophic tissues. Carbon 85-91 triose phosphate/phosphate translocator Zea mays 12-15 9398265-8 1997 The enzymatic activity of MIF was found to be reversibly inhibited by micromolar concentrations of fatty acids with chain lengths of at least 16 carbon atoms. Carbon 145-151 macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mus musculus 26-29 9359857-9 1997 The double bond at C-14,15 is essential for the catalytic activity of LTA4 hydrolase but not for binding to this enzyme. Carbon 19-20 leukotriene A4 hydrolase Homo sapiens 70-84 9474819-2 1997 This system was initially employed in studies to stabilise the enzyme acetylcholinesterase (AChE), which was immobilised on a cobalt phthalocyanine screen-printed carbon electrode to form a biosensor. Carbon 163-169 acetylcholinesterase (Cartwright blood group) Homo sapiens 70-90 9474819-2 1997 This system was initially employed in studies to stabilise the enzyme acetylcholinesterase (AChE), which was immobilised on a cobalt phthalocyanine screen-printed carbon electrode to form a biosensor. Carbon 163-169 acetylcholinesterase (Cartwright blood group) Homo sapiens 92-96 9378988-3 1997 The inhibitory effect of IFN-gamma on poly(I:C)-induced E-selectin was concentration and time dependent and was specific for dsRNA, in that the induction of E-selectin by TNF-alpha, IL-1 beta, thrombin, or LPS was not inhibited significantly by this pretreatment. Carbon 45-47 interferon gamma Homo sapiens 25-34 9378988-3 1997 The inhibitory effect of IFN-gamma on poly(I:C)-induced E-selectin was concentration and time dependent and was specific for dsRNA, in that the induction of E-selectin by TNF-alpha, IL-1 beta, thrombin, or LPS was not inhibited significantly by this pretreatment. Carbon 45-47 interleukin 1 beta Homo sapiens 182-191 9378988-3 1997 The inhibitory effect of IFN-gamma on poly(I:C)-induced E-selectin was concentration and time dependent and was specific for dsRNA, in that the induction of E-selectin by TNF-alpha, IL-1 beta, thrombin, or LPS was not inhibited significantly by this pretreatment. Carbon 45-47 coagulation factor II, thrombin Homo sapiens 193-201 21639317-0 1997 Effect of carbon loading on the extraction properties of C-18 bonded silica used for solid-phase extraction of acidic and basic analytes. Carbon 10-16 Bardet-Biedl syndrome 9 Homo sapiens 57-61 9315631-3 1997 However, cells missing the POR1 gene (delta por1) were able to grow on yeast media containing a nonfermentable carbon source (glycerol) but not on such media at elevated temperature (37 degrees C). Carbon 111-117 porin POR1 Saccharomyces cerevisiae S288C 27-31 9315631-3 1997 However, cells missing the POR1 gene (delta por1) were able to grow on yeast media containing a nonfermentable carbon source (glycerol) but not on such media at elevated temperature (37 degrees C). Carbon 111-117 porin POR1 Saccharomyces cerevisiae S288C 44-48 9315631-12 1997 In contrast, when the VDAC gene from Drosophila melanogaster was expressed in delta por1 yeast cells, VDAC-like channels could be detected in the mitochondria by both bilayer and liposome techniques, yet the cells failed to grow on glycerol at 37 degrees C. Thus, channel-forming activity does not seem to be either necessary or sufficient to restore growth on nonfermentable carbon sources, indicating that VDAC mediates cellular functions that do not depend on the ability to form channels. Carbon 376-382 porin POR1 Saccharomyces cerevisiae S288C 84-88 9299344-1 1997 A model for the alpha-carbon positions in the seven transmembrane helices in the rhodopsin family of G-protein-coupled receptors is presented. Carbon 22-28 rhodopsin Homo sapiens 81-90 9325152-6 1997 The binding constant was derived for each of the NF-kappa B variants: C-p50-1 = 1.01 x 10(10) M(-1); C-p50-2 = 0.92 x 10(10) M(-1); and S-NO-p50 = 0.28 x 10(10) M(-1). Carbon 70-71 nuclear factor kappa B subunit 1 Homo sapiens 49-59 9325152-6 1997 The binding constant was derived for each of the NF-kappa B variants: C-p50-1 = 1.01 x 10(10) M(-1); C-p50-2 = 0.92 x 10(10) M(-1); and S-NO-p50 = 0.28 x 10(10) M(-1). Carbon 70-71 nuclear factor kappa B subunit 1 Homo sapiens 72-75 9315791-11 1997 RESULTS: The 120-mg/kg dose of alpha1-AT-C could not maintain nadir serum protective levels above 70 or 80 mg/dL for the entire 14-day dosing interval in most patients. Carbon 41-42 serpin family A member 1 Homo sapiens 31-40 9309671-1 1997 Our previous studies of insulin action have led us to the finding that insulin acts specifically on the mitochondrial Krebs cycle to stimulate, by 30%, the oxidation of carbons 2 and 3 of pyruvate to CO2. Carbon 169-176 insulin Homo sapiens 24-31 9309671-1 1997 Our previous studies of insulin action have led us to the finding that insulin acts specifically on the mitochondrial Krebs cycle to stimulate, by 30%, the oxidation of carbons 2 and 3 of pyruvate to CO2. Carbon 169-176 insulin Homo sapiens 71-78 9309671-2 1997 Insulin also stimulates the oxidation of both carbons of acetate. Carbon 46-53 insulin Homo sapiens 0-7 9309671-6 1997 The path taken by those carbons affected by insulin is traced through the complete Krebs cycle, and the necessity for this effect to be mitochondrial has been verified by demonstration of the same specific effect of insulin on the oxidation of the 2 and 3 carbons of succinate. Carbon 24-31 insulin Homo sapiens 44-51 9309671-6 1997 The path taken by those carbons affected by insulin is traced through the complete Krebs cycle, and the necessity for this effect to be mitochondrial has been verified by demonstration of the same specific effect of insulin on the oxidation of the 2 and 3 carbons of succinate. Carbon 256-263 insulin Homo sapiens 44-51 9309671-6 1997 The path taken by those carbons affected by insulin is traced through the complete Krebs cycle, and the necessity for this effect to be mitochondrial has been verified by demonstration of the same specific effect of insulin on the oxidation of the 2 and 3 carbons of succinate. Carbon 256-263 insulin Homo sapiens 216-223 9337863-5 1997 In support of this, we find: (i) CNO- inhibits both peroxidative and halogenating activities of MPO and also inhibits the enzyme within intact human neutrophils; (ii) the inhibition is H2O2-dependent, irreversible, accompanied by covalent addition of [14C]CNO- (or a carbon-containing fragment thereof) to the enzyme; (iii) CNO- also inhibits Cl-/H2O2/MPO-mediated bacterial killing. Carbon 267-273 myeloperoxidase Homo sapiens 96-99 9248661-10 1997 Thus, drugs with side chains containing unsaturated carbon-carbon bonds and furan ring systems are associated with CYP inactivation. Carbon 52-58 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 115-118 9211877-8 1997 Elo3p apparently has a broader substrate specificity and is essential for the conversion of 24-carbon acids to 26-carbon species. Carbon 95-101 fatty acid elongase ELO3 Saccharomyces cerevisiae S288C 0-5 9247615-0 1997 Cytochrome P450 hydroxylation of carbon atoms of the alkyl chain of symmetrical N-nitrosodialkylamines by human liver microsomes. Carbon 33-39 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-15 9211877-6 1997 Elo2p appears to be involved in the elongation of fatty acids up to 24 carbons. Carbon 71-78 fatty acid elongase ELO2 Saccharomyces cerevisiae S288C 0-5 9248661-10 1997 Thus, drugs with side chains containing unsaturated carbon-carbon bonds and furan ring systems are associated with CYP inactivation. Carbon 59-65 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 115-118 9245824-2 1997 Streptomyces coelicolor A3(2) utilizes fatty acids of different chain length (C4-C18) as sole carbon and energy sources. Carbon 94-100 Bardet-Biedl syndrome 9 Homo sapiens 81-84 9195917-7 1997 Unexpectedly, however, when the C-terminal domain of the gris ARO/CYC was expressed in a context where aromatase activity was absent, it could modulate the chain length specificity of the tetracenomycin (tcm) minimal PKS, leading to the formation of a novel 18-carbon product in addition to the expected 20-carbon one. Carbon 261-267 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 62-65 9219339-2 1997 The selection of genes that, when overexpressed, are able to suppress the reduced viability upon carbon starvation of the rvs167 mutant strain, has allowed the cloning of the SUR7 gene (Accession Number Z46729x11). Carbon 97-103 amphiphysin Saccharomyces cerevisiae S288C 122-128 9219339-2 1997 The selection of genes that, when overexpressed, are able to suppress the reduced viability upon carbon starvation of the rvs167 mutant strain, has allowed the cloning of the SUR7 gene (Accession Number Z46729x11). Carbon 97-103 Sur7p Saccharomyces cerevisiae S288C 175-179 9195917-7 1997 Unexpectedly, however, when the C-terminal domain of the gris ARO/CYC was expressed in a context where aromatase activity was absent, it could modulate the chain length specificity of the tetracenomycin (tcm) minimal PKS, leading to the formation of a novel 18-carbon product in addition to the expected 20-carbon one. Carbon 261-267 cytochrome c, somatic Homo sapiens 66-69 9197408-3 1997 The Zn(II)2Cys6 cluster shows strong similarity with those of the Saccharomyces cerevisiae carbon metabolism regulatory proteins CAT8 and SIP4. Carbon 91-97 Sip4p Saccharomyces cerevisiae S288C 138-142 9177185-7 1997 These features contrast with the previously reported 15S-lipoxygenase, which oxygenates arachidonic acid mainly at C-15, but also partly at C-12, and for which linoleic acid is an excellent substrate. Carbon 115-116 arachidonate 15-lipoxygenase type B Homo sapiens 53-69 9177185-7 1997 These features contrast with the previously reported 15S-lipoxygenase, which oxygenates arachidonic acid mainly at C-15, but also partly at C-12, and for which linoleic acid is an excellent substrate. Carbon 140-141 arachidonate 15-lipoxygenase type B Homo sapiens 53-69 12223633-1 1997 With the cytochrome pathway inhibited, AOX was able to support considerable growth of cultured tobacco (Nicotiana tabacum cv Petit Havana SR1) cells but the efficiency of carbon utilization decreased dramatically. Carbon 171-177 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 39-42 9163906-4 1997 Growth experiments using glucose as the sole carbon source showed that GLY1 is more important for glycine biosynthesis than SHM1 and SHM2 encoding alternative serine hydroxymethyltransferases. Carbon 45-51 threonine aldolase GLY1 Saccharomyces cerevisiae S288C 71-75 21590081-0 1997 Induction of p53 protein by carbon-ion and proton beam irradiation in two close human lymphoblastoid cell lines with different p53 status. Carbon 28-34 tumor protein p53 Homo sapiens 13-16 21590081-1 1997 In this study, we compared the kinetics of the postirradiation p53 protein expression for carbon ion beam (290 MeV/n, LET 75 keV/mu m) and proton beam (65 MeV) with that of (13)7Cs-gamma ray. Carbon 90-96 tumor protein p53 Homo sapiens 63-66 9159949-8 1997 The data presented demonstrate that the carbonic anhydrase produced from the CAH3 gene is essential to the inorganic carbon-concentrating mechanism in C. reinhardtii and that genomic complementation can be a facile and efficient means for isolating genes associated with defects affecting photosynthesis and other physiological processes in this eukaryotic green alga. Carbon 40-46 uncharacterized protein Chlamydomonas reinhardtii 77-81 9142942-10 1997 Calphostin C abolished both the KGF-mediated decrease in basal albumin flux and the protective effect of KGF against H(2)O(2)-induced increases in permeability. Carbon 0-1 fibroblast growth factor 7 Homo sapiens 32-35 9142942-10 1997 Calphostin C abolished both the KGF-mediated decrease in basal albumin flux and the protective effect of KGF against H(2)O(2)-induced increases in permeability. Carbon 0-1 fibroblast growth factor 7 Homo sapiens 105-108 9132017-6 1997 Thus, PLTP transfers a variety of lipids with two carbon chains and a polar head group. Carbon 50-56 phospholipid transfer protein Homo sapiens 6-10 9132024-3 1997 The first step in this, and other coenzyme B12-dependent reactions, is postulated to be homolysis of the Co-C bond of the cofactor. Carbon 105-106 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 43-46 9084153-1 1997 Expression of the Candida albicans vacuolar aspartic proteinase (APR1) and beta-N-acetylglucosaminidase (HEX1) genes was studied when carbon-starved cells of strains ATCC 10261 and A72 were induced to grow as yeast or as germ tube-forming cells. Carbon 134-140 inositol-3-phosphate synthase INO1 Saccharomyces cerevisiae S288C 65-69 9108260-2 1997 Through its substrates, products and downstream metabolites, methionine synthase is directly involved in the sulphur amino acid pathways, polyamine biosynthesis, biological methylations and one-carbon-unit transfers. Carbon 194-200 5-methyltetrahydrofolate-homocysteine methyltransferase Rattus norvegicus 61-80 9069517-6 1997 CETP activity was significantly higher in the obese children than in nonobese control children, and was correlated with LDL-C, TC:HDL-C, LDL-C:HDL-C, and apo B:apo Al. Carbon 123-125 cholesteryl ester transfer protein Homo sapiens 0-4 9103193-3 1997 Model results show that of the 40 teragrams of carbon produced annually in the Antarctic ice pack, 75 percent was associated with first-year ice and nearly 50 percent was produced in the Weddell Sea. Carbon 47-53 carboxylesterase 2 Homo sapiens 89-92 9103193-3 1997 Model results show that of the 40 teragrams of carbon produced annually in the Antarctic ice pack, 75 percent was associated with first-year ice and nearly 50 percent was produced in the Weddell Sea. Carbon 47-53 carboxylesterase 2 Homo sapiens 141-144 9083049-4 1997 Yeast mutants from the coq5 complementation group lack Q and as a result are respiration-defective and fail to grow on nonfermentable carbon sources. Carbon 134-140 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase Saccharomyces cerevisiae S288C 23-27 9083049-5 1997 A nuclear gene, designated COQ5 was isolated from a yeast genomic library based on its ability to restore growth of a representative coq5 mutant on media containing glycerol as the sole carbon source. Carbon 186-192 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase Saccharomyces cerevisiae S288C 27-31 9083049-5 1997 A nuclear gene, designated COQ5 was isolated from a yeast genomic library based on its ability to restore growth of a representative coq5 mutant on media containing glycerol as the sole carbon source. Carbon 186-192 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase Saccharomyces cerevisiae S288C 133-137 9198539-1 1997 In a continuous flow bioreactor seeded with microbes from municipal activated sludge, complete organic carbon oxidation of simulated graywater (wastewater produced in human residences, excluding toilet wastes) was achieved at dilution rates up to 0.36 h-1 in the presence of 64.1 microM linear alkylbenzenesulfonate (LAS) L-1. Carbon 103-109 immunoglobulin kappa variable 1-16 Homo sapiens 322-325 9042913-6 1997 The mutation causes the substitution of the most 5" cysteine residue by a serine within a highly conserved sequence of the pro(alpha)1(V) C-propeptide domain and causes reduction of collagen V by preventing incorporation of the mutant pro(alpha)1(V) chains in the collagen V trimers. Carbon 138-139 collagen type V alpha 1 chain Homo sapiens 123-137 9042913-6 1997 The mutation causes the substitution of the most 5" cysteine residue by a serine within a highly conserved sequence of the pro(alpha)1(V) C-propeptide domain and causes reduction of collagen V by preventing incorporation of the mutant pro(alpha)1(V) chains in the collagen V trimers. Carbon 138-139 collagen type V alpha 1 chain Homo sapiens 235-249 9245355-4 1997 The parameters for C-C, C-H, and C-O bonds of sp3 and sp2 hybridized carbons and C-N bonds of sp3 carbons were obtained from 606 equations formed from experimental data from 20 substances taken from the literature. Carbon 69-76 Sp2 transcription factor Homo sapiens 54-57 9245355-4 1997 The parameters for C-C, C-H, and C-O bonds of sp3 and sp2 hybridized carbons and C-N bonds of sp3 carbons were obtained from 606 equations formed from experimental data from 20 substances taken from the literature. Carbon 69-76 Sp3 transcription factor Homo sapiens 94-97 9245355-4 1997 The parameters for C-C, C-H, and C-O bonds of sp3 and sp2 hybridized carbons and C-N bonds of sp3 carbons were obtained from 606 equations formed from experimental data from 20 substances taken from the literature. Carbon 19-20 Sp3 transcription factor Homo sapiens 46-49 9245355-4 1997 The parameters for C-C, C-H, and C-O bonds of sp3 and sp2 hybridized carbons and C-N bonds of sp3 carbons were obtained from 606 equations formed from experimental data from 20 substances taken from the literature. Carbon 19-20 Sp2 transcription factor Homo sapiens 54-57 9245355-4 1997 The parameters for C-C, C-H, and C-O bonds of sp3 and sp2 hybridized carbons and C-N bonds of sp3 carbons were obtained from 606 equations formed from experimental data from 20 substances taken from the literature. Carbon 98-105 Sp3 transcription factor Homo sapiens 46-49 9245355-4 1997 The parameters for C-C, C-H, and C-O bonds of sp3 and sp2 hybridized carbons and C-N bonds of sp3 carbons were obtained from 606 equations formed from experimental data from 20 substances taken from the literature. Carbon 98-105 Sp2 transcription factor Homo sapiens 54-57 9245355-4 1997 The parameters for C-C, C-H, and C-O bonds of sp3 and sp2 hybridized carbons and C-N bonds of sp3 carbons were obtained from 606 equations formed from experimental data from 20 substances taken from the literature. Carbon 98-105 Sp3 transcription factor Homo sapiens 94-97 9030521-1 1997 A yeast mutant (cor2-45) in which approximately half of the C terminus of core protein 2 of the cytochrome bc1 complex is lacking due to a frameshift mutation that introduces a stop at codon 197 in the COR2 gene fails to assemble the cytochrome bc1 complex and does not grow on non-fermentable carbon sources that require respiration. Carbon 294-300 ubiquinol--cytochrome-c reductase subunit 2 Saccharomyces cerevisiae S288C 16-20 9030521-1 1997 A yeast mutant (cor2-45) in which approximately half of the C terminus of core protein 2 of the cytochrome bc1 complex is lacking due to a frameshift mutation that introduces a stop at codon 197 in the COR2 gene fails to assemble the cytochrome bc1 complex and does not grow on non-fermentable carbon sources that require respiration. Carbon 294-300 ubiquinol--cytochrome-c reductase subunit 2 Saccharomyces cerevisiae S288C 202-206 9021127-1 1997 Screening of a promoter probe gene bank for DNA sequences that could act as inducible promoters following growth on non-fermentable carbon sources led to the identification of the mitochondrially encoded cytochrome oxidase subunit 1 gene (COX1) as an active sequence. Carbon 132-138 cytochrome c oxidase subunit 1 Saccharomyces cerevisiae S288C 239-243 9006051-8 1997 Expression of prpB to high levels was deleterious to the growth of a prp+ strain on minimal medium supplemented with propionate as a carbon and energy source. Carbon 133-139 methylisocitrate lyase Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 14-18 8995428-12 1997 Mild periodate oxidation of sialic acids to their corresponding seven-carbon (or eight-carbon) sialic acid aldehydes abolished MAG binding, as did further conversion to the corresponding primary alcohols. Carbon 70-76 LOC103161439 Cricetulus griseus 127-130 8985007-3 1997 Calculated intensities from a nonresonant, bond polarizability model optimized for sp2 carbon are also in qualitative agreement with the Raman data, although a resonant Raman scattering process is also taking place. Carbon 87-93 Sp2 transcription factor Homo sapiens 83-86 8995428-12 1997 Mild periodate oxidation of sialic acids to their corresponding seven-carbon (or eight-carbon) sialic acid aldehydes abolished MAG binding, as did further conversion to the corresponding primary alcohols. Carbon 87-93 LOC103161439 Cricetulus griseus 127-130 9421750-0 1997 Grafting of PEO to glass, nitinol, and pyrolytic carbon surfaces by gamma irradiation. Carbon 49-55 twinkle mtDNA helicase Homo sapiens 12-15 8978850-10 1996 The effect of making the analogs more rigid by making the three-carbon chain part of a five-membered ring, but with retention of the methylene replacement for the carboxamide moiety, led to potent PKC inhibitors including anti-substituted pyrrolidine analog 35b and the most potent PKC inhibitor in the series, anti-substituted cyclopentane analog 29b. Carbon 64-70 proline rich transmembrane protein 2 Homo sapiens 197-200 8982278-1 1996 Unsaturated fatty acids of odd carbons, 13:1(12), 17:1(10trans), 19:1(7) and 19:1(10) inhibited release of myeloperoxidase (MPO) from fMet-Leu-Phe-cytochalasin B-treated neutrophils. Carbon 31-38 myeloperoxidase Homo sapiens 107-122 8982278-1 1996 Unsaturated fatty acids of odd carbons, 13:1(12), 17:1(10trans), 19:1(7) and 19:1(10) inhibited release of myeloperoxidase (MPO) from fMet-Leu-Phe-cytochalasin B-treated neutrophils. Carbon 31-38 myeloperoxidase Homo sapiens 124-127 9008404-1 1996 The electrochemical determination of zinc arising from zinc-insulin complexes was investigated and it was demonstrated that zinc in zinc-insulin solution can be measured in the presence of dissolved oxygen by square-wave anodic stripping voltammetry (SWASV) at mercury thin-film electrodes on glassy carbon disc minielectrode and cylindrical carbon fibre microelectrode substrates. Carbon 300-306 insulin Homo sapiens 60-67 9008404-1 1996 The electrochemical determination of zinc arising from zinc-insulin complexes was investigated and it was demonstrated that zinc in zinc-insulin solution can be measured in the presence of dissolved oxygen by square-wave anodic stripping voltammetry (SWASV) at mercury thin-film electrodes on glassy carbon disc minielectrode and cylindrical carbon fibre microelectrode substrates. Carbon 300-306 insulin Homo sapiens 137-144 21619320-5 1996 The free energy of adsorption for the C(2) and C(18) surfaces, -28.5(+-0.1) and -31.5(+-0.1) kJ/mol, respectively, were found to have both electrostatic and nonpolar contributions, with the latter being larger by 50% for the C(2) surface and 100% for the C(18) surface. Carbon 38-39 Bardet-Biedl syndrome 9 Homo sapiens 47-52 9008404-1 1996 The electrochemical determination of zinc arising from zinc-insulin complexes was investigated and it was demonstrated that zinc in zinc-insulin solution can be measured in the presence of dissolved oxygen by square-wave anodic stripping voltammetry (SWASV) at mercury thin-film electrodes on glassy carbon disc minielectrode and cylindrical carbon fibre microelectrode substrates. Carbon 342-348 insulin Homo sapiens 60-67 21619320-5 1996 The free energy of adsorption for the C(2) and C(18) surfaces, -28.5(+-0.1) and -31.5(+-0.1) kJ/mol, respectively, were found to have both electrostatic and nonpolar contributions, with the latter being larger by 50% for the C(2) surface and 100% for the C(18) surface. Carbon 38-39 Bardet-Biedl syndrome 9 Homo sapiens 255-260 9008404-1 1996 The electrochemical determination of zinc arising from zinc-insulin complexes was investigated and it was demonstrated that zinc in zinc-insulin solution can be measured in the presence of dissolved oxygen by square-wave anodic stripping voltammetry (SWASV) at mercury thin-film electrodes on glassy carbon disc minielectrode and cylindrical carbon fibre microelectrode substrates. Carbon 342-348 insulin Homo sapiens 137-144 8954635-0 1996 Tenacious Binding of Fibrinogen and Albumin to Pyrolite Carbon and Biomer Adsorption of bovine fibrinogen from dilute plasma and human serum albumin (HSA) from buffered HSA solution to low-temperature isotropic (LTI) pyrolytic carbon (Pyrolite) and polyetherurethane urea (Biomer) was measured. Carbon 47-55 fibrinogen beta chain Homo sapiens 21-31 8955330-3 1996 In this paper we document that, independent of their inability to substitute for CobT function, cobB mutants are unable to use propionate as a carbon and energy source. Carbon 143-149 NAD-dependent protein deacylase Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 96-100 8954635-0 1996 Tenacious Binding of Fibrinogen and Albumin to Pyrolite Carbon and Biomer Adsorption of bovine fibrinogen from dilute plasma and human serum albumin (HSA) from buffered HSA solution to low-temperature isotropic (LTI) pyrolytic carbon (Pyrolite) and polyetherurethane urea (Biomer) was measured. Carbon 47-55 albumin Homo sapiens 36-43 8954635-0 1996 Tenacious Binding of Fibrinogen and Albumin to Pyrolite Carbon and Biomer Adsorption of bovine fibrinogen from dilute plasma and human serum albumin (HSA) from buffered HSA solution to low-temperature isotropic (LTI) pyrolytic carbon (Pyrolite) and polyetherurethane urea (Biomer) was measured. Carbon 56-62 fibrinogen beta chain Homo sapiens 21-31 8954635-0 1996 Tenacious Binding of Fibrinogen and Albumin to Pyrolite Carbon and Biomer Adsorption of bovine fibrinogen from dilute plasma and human serum albumin (HSA) from buffered HSA solution to low-temperature isotropic (LTI) pyrolytic carbon (Pyrolite) and polyetherurethane urea (Biomer) was measured. Carbon 56-62 albumin Homo sapiens 36-43 8900132-0 1996 Carbon source regulation of PIS1 gene expression in Saccharomyces cerevisiae involves the MCM1 gene and the two-component regulatory gene, SLN1. Carbon 0-6 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 28-32 8954635-0 1996 Tenacious Binding of Fibrinogen and Albumin to Pyrolite Carbon and Biomer Adsorption of bovine fibrinogen from dilute plasma and human serum albumin (HSA) from buffered HSA solution to low-temperature isotropic (LTI) pyrolytic carbon (Pyrolite) and polyetherurethane urea (Biomer) was measured. Carbon 227-233 fibrinogen beta chain Homo sapiens 95-105 8954635-0 1996 Tenacious Binding of Fibrinogen and Albumin to Pyrolite Carbon and Biomer Adsorption of bovine fibrinogen from dilute plasma and human serum albumin (HSA) from buffered HSA solution to low-temperature isotropic (LTI) pyrolytic carbon (Pyrolite) and polyetherurethane urea (Biomer) was measured. Carbon 235-243 fibrinogen beta chain Homo sapiens 95-105 8954635-4 1996 Under all conditions, fibrinogen retention by Pyrolite was greater than that by Biomer. Carbon 46-54 fibrinogen beta chain Homo sapiens 22-32 8954635-6 1996 Antibody binding (normalized to the amount of fibrinogen adsorbed) to plasma preadsorbed Pyrolite was much less than that to preadsorbed Biomer. Carbon 89-97 fibrinogen beta chain Homo sapiens 46-56 8929407-3 1996 These findings strongly correlate with astronomical observations and explain a higher [c-C3H]/[l-C3H] ratio in the dark cloud TMC-1 than in the carbon star IRC+10216. Carbon 24-25 transmembrane channel like 1 Homo sapiens 126-131 8900132-9 1996 Thus, PIS1 gene expression is unique among the phospholipid biosynthetic structural genes because it is uncoupled from the inositol response and regulated in response to the carbon source. Carbon 174-180 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 6-10 8900132-10 1996 This is the first example in yeast of a complete circuit linking a stimulus (carbon source) to gene regulation (PIS1) using a two-component regulator (SLN1). Carbon 77-83 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 112-116 8970157-1 1996 We show that cells deleted for SNF3, HXT1, HXT2, HXT3, HXT4, HXT6, and HXT7 do not take up glucose and cannot grow on media containing glucose as a sole carbon source. Carbon 153-159 glucose sensor Saccharomyces cerevisiae S288C 31-35 21619257-6 1996 The detection limit for 4-amino-TEMPO is 50 muM at an unmodified electrode and 5 muM at a Nafion-coated carbon fiber electrode. Carbon 104-110 latexin Homo sapiens 81-84 8912642-2 1996 The method is based on the detection of the insulin surrogate 5-hydroxytryptamine (5-HT) by carbon fibre microelectrodes implanted in the islets. Carbon 92-98 insulin Homo sapiens 44-51 8938388-8 1996 Because of the peak broadening caused by the strong sorption of the analytes on carbon, the carbon-packed precolumns were eluted by a separate stream of 0.1 ml/min acetonitrile which was mixed with the gradient LC eluent in front of the C18 analytical column. Carbon 92-98 Bardet-Biedl syndrome 9 Homo sapiens 237-240 11667621-4 1996 Instead the ring is closed by a bond from the indole nitrogen of Trp-1 to the beta-carbon of Trp-2. Carbon 83-89 tRNA-Pro (anticodon AGG) 2-6 Homo sapiens 93-98 8842143-13 1996 These similarities strongly suggest that HypX/HoxX have dual functions: binding of the C1 donor N10-formyltetrahydrofolate and transfer of the C1 to an unknown substrate, and catalysis of a reaction involving polarization of the C = O bond of an X-CO-SCoA substrate. Carbon 87-88 HPT Homo sapiens 41-45 8891872-6 1996 We used these drugs to evaluate the affinity of C and N sites in various human tissues involved in the cardiovascular actions of ACE and used [125I]Ro31-8472 as ligand. Carbon 48-49 angiotensin I converting enzyme Homo sapiens 129-132 28307743-8 1996 That CO2-stimulated increase in annual soil carbon efflux is more than twice as big as the increase in aboveground net primary productivity (NPPa) and approximately 60% of NPPa in this grassland in the current CO2 environment. Carbon 44-50 natriuretic peptide A Homo sapiens 172-176 9984485-0 1996 Separation of the sp3 and sp2 components in the C1s photoemission spectra of amorphous carbon films. Carbon 87-93 Sp3 transcription factor Homo sapiens 18-21 9984485-0 1996 Separation of the sp3 and sp2 components in the C1s photoemission spectra of amorphous carbon films. Carbon 87-93 Sp2 transcription factor Homo sapiens 26-29 8794768-2 1996 Proton, nitrogen, and carbon chemical shift assignments have been made for the SH2 domain of Grb2. Carbon 22-28 growth factor receptor bound protein 2 Homo sapiens 93-97 8880344-0 1996 Net carbon flux across subcutaneous adipose tissue after a standard meal in normal-weight and insulin-resistant obese subjects. Carbon 4-10 insulin Homo sapiens 94-101 8707282-4 1996 Fractional synthesis rates of albumin were normal in Child A cirrhosis (7.6 +/- 2.2%d), but were lower in both Child B (3.5 +/- 0.8%d) and C (4.5 +/- 2.8%d). Carbon 53-54 albumin Homo sapiens 30-37 8761428-5 1996 Furthermore, the enzymatic activity of 10-formyltetrahydrofolate dehydrogenase, the terminal enzyme in the catabolism of the ring-2-carbon of histidine to CO2, was diminished by 32% in methotrexate-treated animals. Carbon 132-138 aldehyde dehydrogenase 1 family, member L1 Rattus norvegicus 39-78 8709137-2 1996 Replacement of the inner urea NH and addition of a methyl group to generate a C-3 quaternary carbon resulted in acetamide 6, which showed CCK-A receptor binding selectivity and sub-micromolar agonist activity in vitro. Carbon 93-99 cholecystokinin A receptor Mus musculus 138-152 8806070-6 1996 Precoating fibronectin or laminin on the carbon-deposited polymer surface brought about cell adhesion and proliferation in the carbon-deposited region, but not in the non-carbon-deposited region. Carbon 41-47 fibronectin 1 Homo sapiens 11-22 8806070-6 1996 Precoating fibronectin or laminin on the carbon-deposited polymer surface brought about cell adhesion and proliferation in the carbon-deposited region, but not in the non-carbon-deposited region. Carbon 127-133 fibronectin 1 Homo sapiens 11-22 8806070-6 1996 Precoating fibronectin or laminin on the carbon-deposited polymer surface brought about cell adhesion and proliferation in the carbon-deposited region, but not in the non-carbon-deposited region. Carbon 127-133 fibronectin 1 Homo sapiens 11-22 31159058-0 1996 Reduction of Carryover of Aflatoxin from Cow Feed to Milk by Addition of Activated Carbons. Carbon 83-90 Weaning weight-maternal milk Bos taurus 53-57 16535322-0 1996 Stable Carbon Isotope Evidence for Atmospheric CO(inf2) Uptake by Cyanobacterial Surface Scums in a Eutrophic Lake. Carbon 7-13 inverted formin 2 Homo sapiens 47-54 8785502-0 1996 Leucine side-chain rotamers in a glycophorin A transmembrane peptide as revealed by three-bond carbon-carbon couplings and 13C chemical shifts. Carbon 95-101 glycophorin A (MNS blood group) Homo sapiens 33-46 8785502-0 1996 Leucine side-chain rotamers in a glycophorin A transmembrane peptide as revealed by three-bond carbon-carbon couplings and 13C chemical shifts. Carbon 102-108 glycophorin A (MNS blood group) Homo sapiens 33-46 8670793-7 1996 A pip2 deletion strain is impaired in growth on oleate as sole carbon source and the induction of beta-oxidation enzymes is abolished. Carbon 63-69 oleate-activated transcription factor PIP2 Saccharomyces cerevisiae S288C 2-6 8901643-8 1996 Simulations of the approach of the benzylic carbon by the nucleophilic amino acid His40 or His57 through an SN2 displacement on the halomethyl group of AA 231-1 were performed. Carbon 44-50 solute carrier family 38 member 5 Homo sapiens 108-111 8647850-0 1996 The mechanism of the acyl-carbon bond cleavage reaction catalyzed by recombinant sterol 14 alpha-demethylase of Candida albicans (other names are: lanosterol 14 alpha-demethylase, P-45014DM, and CYP51). Carbon 26-32 sterol 14-demethylase Saccharomyces cerevisiae S288C 195-200 8641288-2 1996 A disruption of both MSN2 and MSN4 genes results in a higher sensitivity to different stresses, including carbon source starvation, heat shock and severe osmotic and oxidative stresses. Carbon 106-112 stress-responsive transcriptional activator MSN4 Saccharomyces cerevisiae S288C 30-34 8868234-10 1996 Primer extension analysis of these RNAs revealed different transcription initiation sites for the celA gene when cells were grown with cellulose or cellobiose as the carbon source. Carbon 166-172 kil protein Escherichia coli 98-102 8638935-1 1996 Cytochrome P450 enzymes oxidize aldehydes either to the corresponding acid or, via a decarboxylation mechanism, to an olefin one carbon shorter than the parent substrate. Carbon 129-135 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-15 8681412-1 1996 The adsorption behavior of serum albumin onto the surface of platinum, gold, and glassy carbon electrodes was studied in relation to the electrode potential, by using cyclic voltammetry and a quartz-crystal microbalance. Carbon 88-94 albumin Homo sapiens 27-40 8620865-3 1996 & Tatchell, K. (1986) Genetics 113, 247-264] by selection of ras2::LEU2 revertants that grew on non-fermentable carbon sources. Carbon 116-122 3-isopropylmalate dehydrogenase Saccharomyces cerevisiae S288C 71-75 8723668-3 1996 The relationship between the variations in carbon isotope composition of CO2 of expired air and energy exchange in cells of insulin-dependent tissues of the organism is substantiated. Carbon 43-49 insulin Homo sapiens 124-131 8867339-6 1996 It was found that the Trp residue in alpha-MSH and in MSH-II is positioned around the carbons 6 and 8 of the aliphatic chain. Carbon 86-93 proopiomelanocortin Homo sapiens 37-46 8830047-0 1996 C-NMR study on the interaction of medium-chain acyl-CoA dehydrogenase with acetoacetyl-CoA. Carbon 0-1 acyl-CoA dehydrogenase medium chain Sus scrofa 34-69 8626239-3 1996 Biosynthetic studies using 13C- and 2H-labeled compounds revealed that the carbon skeletons of cochleamycins A and B were derived from eight acetic acid units and one propionic acid unit with the introduction of an acetoxy group at C-10, which was replaced by an isobutyryl residue derived from valine in cochleamycins A2 and B2. Carbon 75-81 homeobox C10 Homo sapiens 232-236 8830047-5 1996 While C(4) underwent a small upfield shift, the other carbons complexed with MCAD. Carbon 54-61 acyl-CoA dehydrogenase medium chain Sus scrofa 77-81 8830047-4 1996 The chemical shift values for free acetoacetyl-CoA were 198.5, 59.9, 208.8, and 32.8 ppm for C(1), C(2), C(3), and C(4), respectively, which shifted to 181.3, 103.4, 192.3, and 29.9 ppm, respectively, when acetoacetyl-CoA was complexed with MCAD. Carbon 47-48 acyl-CoA dehydrogenase medium chain Sus scrofa 241-245 8568822-4 1996 Examination of a series of 5-(alkyloxy)tryptamine derivatives demonstrated that compounds with unbranched alkyl groups of up to eight carbon atoms bind with high affinity at human 5-HT1D beta receptors (Ki < 5 nM) but demonstrate less than 50-fold selectivity relative to 5-HT1A receptors. Carbon 134-140 5-hydroxytryptamine receptor 1B Homo sapiens 180-191 8904082-1 1996 The effect of neuropeptide Y on the number of perivascular carbon deposits, assessed as a measure of lung vascular permeability, was examined in isolated perfused lung preparations of rats. Carbon 59-65 neuropeptide Y Rattus norvegicus 14-28 8904082-2 1996 The number of carbon particle deposits after bronchial application of neuropeptide Y was increased in a dose-dependent manner. Carbon 14-20 neuropeptide Y Rattus norvegicus 70-84 8904082-4 1996 Peptide YY, an analog of neuropeptide Y, demonstrated a much lower potency for increasing the number of carbon deposits, and neuropeptide Y-(18-36), which elicits a weak antagonist action on the neuropeptide Y Y3 receptor, significantly decreased the neuropeptide Y-induced increase. Carbon 104-110 neuropeptide Y Rattus norvegicus 25-39 8568822-5 1996 Alkyl groups longer than eight carbon atoms impart reduced affinity for 5-HT1A receptors whereas groups longer than nine carbon atoms lead to compounds with reduced affinity at 5-HT1D beta receptors. Carbon 121-127 5-hydroxytryptamine receptor 1B Homo sapiens 177-188 8828163-4 1996 In the assembled biosensor, the AChE modified mesh was placed over a glassy carbon electrode and the response to 4-aminophenylacetate, used as substrate, was monitored via the enzymatic reaction product, 4-aminophenol, by oxidation at +0.25 V vs. SSCE. Carbon 76-82 acetylcholinesterase (Cartwright blood group) Homo sapiens 32-36 8869746-9 1996 The structure of the rTS proteins suggests they are expected to have catalytic activity which involves proton abstraction from an alpha-carbon of a carboxyl group. Carbon 136-142 RT1 class Ib, locus EC2 Rattus norvegicus 21-24 8924604-9 1996 From these homology modeling and docking data, the difference in stereoselectivity between GST 3-3 and GST 4-4 for the R- and S-configured carbons of the oxirane moiety could be rationalized. Carbon 139-146 glutathione S-transferase mu 1 Rattus norvegicus 91-98 8549771-3 1995 The Saccharomyces cerevisiae Pas3p, a homologue of per9p, restored peroxisome biogenesis and peroxisomal protein import in the delta per9 mutant, allowing it to grow again on methanol as sole carbon and energy source. Carbon 192-198 Pex3p Saccharomyces cerevisiae S288C 29-34 8749844-3 1995 The binding site is saturated with atoms (sp3 carbon atoms in the present implementation) that form molecules under the influence of a potential function that joins atoms to each other with the correct stereochemistry. Carbon 46-52 Sp3 transcription factor Homo sapiens 42-45 9980956-0 1995 sp3 content of mass-selected ion-beam-deposited carbon films determined by inelastic and elastic electron scattering. Carbon 48-54 Sp3 transcription factor Homo sapiens 0-3 8787809-3 1995 The activity shown by those Michael acceptors with a beta carbon hindered by an alkyl substituent was always lower or almost null. Carbon 58-64 amyloid beta precursor protein Homo sapiens 51-57 8749844-5 1995 The generalized potential function allows atoms to sample a continuous parameter space that includes the Cartesian coordinates and their occupancy and type, e.g., the method allows change of an sp3 carbon into an sp2 carbon or oxygen. Carbon 198-204 Sp3 transcription factor Homo sapiens 194-197 8749844-5 1995 The generalized potential function allows atoms to sample a continuous parameter space that includes the Cartesian coordinates and their occupancy and type, e.g., the method allows change of an sp3 carbon into an sp2 carbon or oxygen. Carbon 198-204 Sp2 transcription factor Homo sapiens 213-216 7574675-5 1995 As previously determined for the APPA-trypsin complex, the carbonyl carbon atom of APPA forms a covalent bond with O gamma of Ser195 of thrombin to yield a "transition-state" analog of the tetrahedral intermediate. Carbon 59-65 coagulation factor II, thrombin Homo sapiens 136-144 8749844-5 1995 The generalized potential function allows atoms to sample a continuous parameter space that includes the Cartesian coordinates and their occupancy and type, e.g., the method allows change of an sp3 carbon into an sp2 carbon or oxygen. Carbon 217-223 Sp3 transcription factor Homo sapiens 194-197 8749844-5 1995 The generalized potential function allows atoms to sample a continuous parameter space that includes the Cartesian coordinates and their occupancy and type, e.g., the method allows change of an sp3 carbon into an sp2 carbon or oxygen. Carbon 217-223 Sp2 transcription factor Homo sapiens 213-216 7490730-1 1995 A novel series of nonpeptide angiotensin II (A II) antagonists containing a pyrimidinone ring which carries a C-linked biphenyltetrazole moiety and a carboxyheteroaryl group on the 3-position have been prepared. Carbon 110-111 angiotensinogen Rattus norvegicus 45-49 7503767-7 1995 The IC50s calculated from their Ki values were in the order of F-2 < C-2 < FZ < CZ < C-4 << F-1, indicating that C-2 and F-2 exhibit higher affinities for D2-R than the parent drugs, whereas affinities of other metabolites were 1 to 2 orders of magnitude less than those of C-2 and F-2. Carbon 5-6 coagulation factor II Rattus norvegicus 63-66 7503767-7 1995 The IC50s calculated from their Ki values were in the order of F-2 < C-2 < FZ < CZ < C-4 << F-1, indicating that C-2 and F-2 exhibit higher affinities for D2-R than the parent drugs, whereas affinities of other metabolites were 1 to 2 orders of magnitude less than those of C-2 and F-2. Carbon 5-6 coagulation factor II Rattus norvegicus 139-142 7503767-7 1995 The IC50s calculated from their Ki values were in the order of F-2 < C-2 < FZ < CZ < C-4 << F-1, indicating that C-2 and F-2 exhibit higher affinities for D2-R than the parent drugs, whereas affinities of other metabolites were 1 to 2 orders of magnitude less than those of C-2 and F-2. Carbon 5-6 coagulation factor II Rattus norvegicus 139-142 7588747-2 1995 Transcription of the QCR8 gene, encoding subunit VIII of the Saccharomyces cerevisiae mitochondrial ubiquinol-cytochrome c oxidoreductase (QCR), is controlled by the carbon-source-dependent heme-activator protein complex HAP2/3/4 and the general transcriptional regulators autonomous replication-site-binding factor ABF1 and centromere-binding and promoter-binding factor CPF1. Carbon 166-172 DNA-binding protein ABF1 Saccharomyces cerevisiae S288C 316-320 7577227-1 1995 Negatively stained electron microscope images are presented, showing the nucleation of two-dimensional (2-D) crystals of human erythrocyte catalase produced on mica by the negative staining-carbon film technique. Carbon 190-196 catalase Homo sapiens 139-147 9383467-7 1995 CONCLUSIONS: In this work, we have provided a relatively rare example of carbon-carbon bond formation in a pool synthesis and have discovered a potentially useful acetylcholinesterase inhibitor. Carbon 73-79 acetylcholinesterase (Cartwright blood group) Homo sapiens 163-183 9383467-7 1995 CONCLUSIONS: In this work, we have provided a relatively rare example of carbon-carbon bond formation in a pool synthesis and have discovered a potentially useful acetylcholinesterase inhibitor. Carbon 80-86 acetylcholinesterase (Cartwright blood group) Homo sapiens 163-183 7669076-4 1995 The most potent analogue has a 4-iodine substituent and eight carbon atoms in its basic side-chain with IC50 values of 38 microM for PKC inhibition and 0.3 microM for calmodulin antagonism, which compares with 92 and 6.8 microM, respectively, for tamoxifen. Carbon 62-68 calmodulin 1 Homo sapiens 167-177 7642509-3 1995 revealed induction of transcription of the celA gene when barley beta-glucan was used as carbon source, while no celA mRNA was detected after growth on cellobiose. Carbon 89-95 kil protein Escherichia coli 43-47 7622489-3 1995 Lengthening the side chain is tolerated by each cytochrome P450 isoform such that 25-hydroxylation or 24-hydroxylation continues to occur at the same rate as in the native side chain, while the site of hydroxylation remains the same for the liver enzyme in that CYP27 continues to hydroxylate at C-25 and C-27 (minor) despite the two-carbon-atom extension. Carbon 262-263 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 48-63 7622489-3 1995 Lengthening the side chain is tolerated by each cytochrome P450 isoform such that 25-hydroxylation or 24-hydroxylation continues to occur at the same rate as in the native side chain, while the site of hydroxylation remains the same for the liver enzyme in that CYP27 continues to hydroxylate at C-25 and C-27 (minor) despite the two-carbon-atom extension. Carbon 296-297 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 48-63 7622489-3 1995 Lengthening the side chain is tolerated by each cytochrome P450 isoform such that 25-hydroxylation or 24-hydroxylation continues to occur at the same rate as in the native side chain, while the site of hydroxylation remains the same for the liver enzyme in that CYP27 continues to hydroxylate at C-25 and C-27 (minor) despite the two-carbon-atom extension. Carbon 334-340 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 48-63 7628449-3 1995 In addition, mdh3-disrupted cells were unable to grow on oleate whereas growth on other non-fermentable carbon sources was normal, suggesting that MDH3 is involved in the reoxidation of NADH generated during fatty acid beta-oxidation rather than functioning as part of the glyoxylate cycle. Carbon 104-110 malate dehydrogenase MDH3 Saccharomyces cerevisiae S288C 13-17 7542701-5 1995 Structure-activity analysis suggests that effective aFGF partners all contain an amine group separated from a catechol nucleus by two carbons. Carbon 134-141 fibroblast growth factor 1 Mus musculus 52-56 7483664-2 1995 Mechanistic criteria, based on the side-chain fragmentation reactions of aromatic cation radicals, involving the cleavage of a beta bond (i.e. C-H, C-Si and C-S) have been developed for the detection of electron transfer mechanisms in oxidative processes of alkylbenzenes and aromatic sulphides. Carbon 143-144 amyloid beta precursor protein Homo sapiens 125-131 7483670-15 1995 In contrast, meta-substituted N,N-dimethyl benzylamine analogues are weak substrates for MAO B with oxidation occurring exclusively at the benzyl carbon. Carbon 146-152 monoamine oxidase B Bos taurus 89-94 7546040-0 1995 Enzymatic and electrochemical reactions of catalase immobilized on carbon materials. Carbon 67-73 catalase Homo sapiens 43-51 7483664-2 1995 Mechanistic criteria, based on the side-chain fragmentation reactions of aromatic cation radicals, involving the cleavage of a beta bond (i.e. C-H, C-Si and C-S) have been developed for the detection of electron transfer mechanisms in oxidative processes of alkylbenzenes and aromatic sulphides. Carbon 148-149 amyloid beta precursor protein Homo sapiens 125-131 7483670-17 1995 The consequences of these results on the possible mechanisms (aminium cation radical, H abstraction, and nucleophilic mechanism) for C-H bond cleavage proposed for MAO B are discussed. Carbon 133-134 monoamine oxidase B Bos taurus 164-169 7750534-0 1995 Transcriptional regulation of the yeast vacuolar aminopeptidase yscI encoding gene (APE1) by carbon sources. Carbon 93-99 aminopeptidase Saccharomyces cerevisiae S288C 49-63 7767513-7 1995 Reduction of ferricytochrome c and production of luminol-dependent chemiluminescence via SOD-inhibitable reactions confirmed the spontaneous production of O2-. Carbon 4-5 superoxide dismutase 1 Homo sapiens 89-92 7676479-6 1995 A finer analysis was made of a series of A-ring phenols showing the high degree of glucocorticoid receptor and progesterone receptor binding that can be generated by certain C-11-substitutions despite the presence of the phenolic A-ring characteristic of estrogen receptor-specific binding. Carbon 174-175 nuclear receptor subfamily 3 group C member 1 Homo sapiens 83-106 7797485-4 1995 Disruption of VMA8 resulted in a mutant exhibiting pH-sensitive growth, slowed growth under all conditions, and an inability to grow on nonfermentable carbon sources. Carbon 151-157 H(+)-transporting V1 sector ATPase subunit D Saccharomyces cerevisiae S288C 14-18 7789524-7 1995 The T1 relaxation rates of the individual Met methyl carbons in the three forms of CaM indicate that those in Ca(2+)-CaM have the highest mobility. Carbon 53-60 calmodulin 1 Homo sapiens 83-86 7789524-7 1995 The T1 relaxation rates of the individual Met methyl carbons in the three forms of CaM indicate that those in Ca(2+)-CaM have the highest mobility. Carbon 53-60 calmodulin 1 Homo sapiens 117-120 16535055-1 1995 Two methylotrophic bacterial strains, TR3 and PSCH4, capable of growth on methanesulfonic acid as the sole carbon source were isolated from the marine environment. Carbon 107-113 thioredoxin reductase 2 Homo sapiens 38-41 7562404-2 1995 The pharmacological activities of these acyl derivatives, as assessed by their hypoglycemic effects after intravenous administration, were reduced upon increasing the carbon number of the fatty acid(s) chemically attached to native insulin. Carbon 167-173 insulin Homo sapiens 232-239 7750534-1 1995 Transcription of the vacuolar aminopeptidase yscI-encoding gene (APE1) is regulated by the carbon source used for yeast growth, responding to carbon catabolite repression. Carbon 91-97 aminopeptidase Saccharomyces cerevisiae S288C 30-44 7891095-6 1995 [octyl-3H]-Octyl-BDPO is an improved probe for NTE in terms of its potency, reactivity, selectivity, and the formation of 3H-labeled NTE with a stable phosphorus-carbon bond. Carbon 162-168 patatin like phospholipase domain containing 6 Homo sapiens 47-50 7558195-1 1995 A Pseudomonas strain NGK1 capable of degrading naphthalene as a sole carbon source was isolated from biological waste treatment effluent. Carbon 69-75 potassium voltage-gated channel subfamily A member 2 Homo sapiens 21-25 7615646-10 1995 Staurosporine, calphostin C, H-7, and substances that elevate cellular levels of cAMP, like PGE2, also reduced basal expression and synthesis of TIMP-1. Carbon 26-27 TIMP metallopeptidase inhibitor 1 Homo sapiens 145-151 7891095-6 1995 [octyl-3H]-Octyl-BDPO is an improved probe for NTE in terms of its potency, reactivity, selectivity, and the formation of 3H-labeled NTE with a stable phosphorus-carbon bond. Carbon 162-168 patatin like phospholipase domain containing 6 Homo sapiens 133-136 7867715-3 1995 The CH-271 fusion fragment, in which the cell-binding domain (C-274) of FN is adjacent to the heparin-binding domain (H-271), promoted cell spreading more efficiently than C-274, H-271, or their mixture (C-274 + H-271) over a 60-min incubation. Carbon 4-5 fibronectin 1 Homo sapiens 72-74 7900786-9 1995 The formula for vTCA during administration of [2-13C]acetate is as follows: vTCA = M[(C-2ssLC-4)/[C-4ss(LC-4-LC-2)]], where C-2ss and C-4ss represent steady-state fractional enrichment, LC-2 and LC-4 represent dominant rate constants of C-2 and C-4 of glutamate, respectively, and M is the sum of concentrations of aspartate, glutamate, and intermediates of the CAC. Carbon 18-19 complement C4A Rattus norvegicus 92-95 7791577-6 1995 Resting fibrinogen concentrations (RFC) before conditioning were similar between the two groups, and demonstrated no change in the C group (242.9 +/- 40.3 mg.dl-1 vs 247.4 +/- 38.7 mg.dl-1, P > 0.05) after conditioning. Carbon 37-38 fibrinogen beta chain Homo sapiens 8-18 7893683-9 1995 Our results indicate that an alkyl chain length of 5 carbons is the critical length necessary for p-glycoprotein to affect membrane transport of DiOCn(3) but not to protect the cells from the cytotoxicity of the dyes. Carbon 53-60 ATP binding cassette subfamily B member 1 Homo sapiens 98-112 7867715-3 1995 The CH-271 fusion fragment, in which the cell-binding domain (C-274) of FN is adjacent to the heparin-binding domain (H-271), promoted cell spreading more efficiently than C-274, H-271, or their mixture (C-274 + H-271) over a 60-min incubation. Carbon 62-63 fibronectin 1 Homo sapiens 72-74 7551815-7 1995 Deposition of the carbon from [14C] acetate into glycogen in the CCl4-injured liver was larger than that in the normal liver at 0 mM glucose (0.81 +/- 0.15 mumol vs 0.32 +/- 0.06 mumol, P < 0.01), but was similar to the normal at 20 mM glucose. Carbon 18-24 C-C motif chemokine ligand 4 Rattus norvegicus 65-69 7766851-5 1995 Results indicate that the C=N bond of PBN is cleaved by A beta in what we hypothesize is a radical addition-fragmentation reaction. Carbon 26-27 amyloid beta precursor protein Homo sapiens 56-62 7836427-5 1995 (i) When a single cis-carbon-carbon double bond (delta) is incorporated into a saturated diacylphosphatidylcholine molecule at any position within the central segment of the long sn-2 acyl chain, the resulting monoenoic lipid molecules will, in excess water, exhibit reduced phase transition temperature (Tm) and transition enthalpy (delta H) as they undergo the gel to liquid-crystalline phase transition. Carbon 22-28 solute carrier family 38 member 5 Homo sapiens 179-183 7836427-5 1995 (i) When a single cis-carbon-carbon double bond (delta) is incorporated into a saturated diacylphosphatidylcholine molecule at any position within the central segment of the long sn-2 acyl chain, the resulting monoenoic lipid molecules will, in excess water, exhibit reduced phase transition temperature (Tm) and transition enthalpy (delta H) as they undergo the gel to liquid-crystalline phase transition. Carbon 29-35 solute carrier family 38 member 5 Homo sapiens 179-183 7551815-5 1995 Deposition of the carbon from [14C] glucose into glycogen was stimulated at high glucose levels and was markedly reduced in the CCl4-injured liver compared to the normal liver (0.58 +/- 0.33 mumol vs 1.44 +/- 0.20 mumol at 20 mM, P < 0.01). Carbon 18-24 C-C motif chemokine ligand 4 Rattus norvegicus 128-132 7827090-8 1995 In both the rhodopsin and bathorhodopsin models, we have included a structural water molecule hydrogen bonded with the Schiff base to account for the high C = N stretching vibrations previously observed. Carbon 155-156 rhodopsin Homo sapiens 12-21 7533622-12 1995 A comparison of the potencies of ethyl-, iso-propyl-, n-propyl-, t-butyl- and n-butyl-isothioureas on iNOS activity shows that the inhibitory activity of S-substituted isothioureas declines sharply if the side chain exceeds 2 carbon atoms in length. Carbon 226-232 nitric oxide synthase 2 Rattus norvegicus 102-106 7827090-3 1995 We have used the observed 13C NMR chemical shifts of the conjugated retinal carbons in combination with semiempirical molecular orbital calculations to establish the major charge interactions in the retinal binding site of rhodopsin and its primary photoproduct, bathorhodopsin. Carbon 76-83 rhodopsin Homo sapiens 223-232 7832757-7 1995 Like the native enzyme, rCAT was capable of acylating carnitine with a preference for small-chain acyl-CoAs of carbon chain lengths C2-C4. Carbon 111-117 catalase Rattus norvegicus 24-28 7857870-8 1995 The CYP450 enzymes that hydroxylate the C19 carbon of androgens (aromatase) and the C18 carbon of corticosterone (aldosterone synthase) were selected as target enzymes because they are terminal enzymes of biosynthetic pathways which hydroxylate specific angular methyl groups. Carbon 44-50 Bardet-Biedl syndrome 9 Homo sapiens 84-87 7749068-7 1995 In the monocytic cells, THP-1, gamma 2 mRNA was highly induced by IFN-gamma, whereas in the B-cell line, Daudi, gamma 2 mRNA was transiently induced by IFN-alpha and poly(I).poly(C), and not by IFN-gamma. Carbon 179-180 tryptophanyl-tRNA synthetase 1 Homo sapiens 112-119 7857870-8 1995 The CYP450 enzymes that hydroxylate the C19 carbon of androgens (aromatase) and the C18 carbon of corticosterone (aldosterone synthase) were selected as target enzymes because they are terminal enzymes of biosynthetic pathways which hydroxylate specific angular methyl groups. Carbon 88-94 Bardet-Biedl syndrome 9 Homo sapiens 84-87 7798323-5 1994 These mutations block apoptosis induced by dexamethasone, gamma irradiation, and c-AMP treatment before the point where Bcl-2 exerts its protective effect. Carbon 19-20 B cell leukemia/lymphoma 2 Mus musculus 120-125 7798231-4 1994 The modeled transition state structures for the hydrolysis promoted by the alpha-glucosidase and the glucoamylase both bear significant oxocarbonium ion character, with the D-glucosyl residue having a flattened 4C1 conformation and a C-1-O-5 bond order of 1.92, even though opposite D-glucose anomers were produced from the substrate. Carbon 212-213 alpha-glucosidase Beta vulgaris subsp. vulgaris 75-92 7895165-3 1994 In vitro, CLIP dissociation from DR alpha beta dimers occurs at different rates depending on the allele, and is facilitated by low pH and by detergents containing 8-10 carbon unbranched hydrocarbons, or by primary aliphatic amines or carboxylic acids. Carbon 168-174 solute carrier family 26 member 3 Homo sapiens 33-41 8577261-2 1995 Five of them were capable of producing extracellular alpha-mannosidase and alpha-mannanase on yeast mannan as the sole carbon substrate, and they were tentatively identified to the genus level as Arthrobacter, Streptomyces, Pseudomonas, Bacillus and Acinetobacter. Carbon 119-125 alpha-mannosidase Saccharomyces cerevisiae S288C 53-70 7527332-10 1994 Dextran sulfate, pentosan polysulfate, and fucoidan, which are composed of different saccharide units but contain O-sulfate groups in the 2 or 3 carbon positions, also inhibited IGFBP-5 degradation. Carbon 145-151 insulin like growth factor binding protein 5 Homo sapiens 178-185 8074675-0 1994 Cytochrome c oxidase in proteoliposomes visualised by platinum-carbon and by tungsten-tantalum shadowing: image analysis. Carbon 63-69 cytochrome c, somatic Homo sapiens 0-12 7846154-6 1994 We also investigated whether light-induced changes in nitrogen to carbon ratios might exert a metabolic regulation of the ASN1 mRNA accumulation. Carbon 66-72 glutamine-dependent asparagine synthase 1 Arabidopsis thaliana 122-126 7846154-9 1994 These findings suggest that the expression of the ASN1 gene is under the metabolic control of the nitrogen to carbon ratio in cells. Carbon 110-116 glutamine-dependent asparagine synthase 1 Arabidopsis thaliana 50-54 7846154-11 1994 We have put forth a working model suggesting that when nitrogen to carbon ratios are high, the gene product of ASN1 functions to re-direct the flow of nitrogen into asparagine, which acts as a shunt for storage and/or long-distance transport of nitrogen. Carbon 67-73 glutamine-dependent asparagine synthase 1 Arabidopsis thaliana 111-115 24226388-8 1994 reactions with the alkyl esters of 1,2- and l,3-benzenedicarboxylic acids are attributed to SN2 displacement at the O-alkyl carbon. Carbon 124-130 solute carrier family 38 member 5 Homo sapiens 92-95 7929400-7 1994 The mechanism of action of 15-lipoxygenase acting as an LTA4 synthase is proposed to involve removing the pro-R hydrogen atom at carbon-10 of 5(S)-HPETE, which is antarafacial to the hydroperoxy group to yield LTA4. Carbon 129-135 arachidonate 15-lipoxygenase Homo sapiens 27-42 11539187-3 1994 This definitive structural characterization of a carbon cluster in the intermediate size range between C10 and C20 is in apparent conflict with theoretical calculations, which predict that clusters of this size should exist as planar monocyclic rings. Carbon 49-55 homeobox C10 Homo sapiens 103-106 7913507-3 1994 The bis(N,N-dialkylguanyl) disulfide and carbon analogs 14a-c were 3-4 times more potent than their respective controls in displacing [3H]NPY from rat brain membrane homogenates with IC50"s ranging from 15 to 18 microM and maintained selectivity for the benextramine-sensitive, Y1 binding site population. Carbon 41-47 neuropeptide Y Rattus norvegicus 138-141 7982561-4 1994 In general, Adh genotypes with higher ADH activity exhibit a twofold difference in relative carbon flux from malate into lactate and alanine vs. alpha,alpha-trehalose compared to low ADH activity genotypes. Carbon 92-98 Alcohol dehydrogenase Drosophila melanogaster 12-15 7982561-4 1994 In general, Adh genotypes with higher ADH activity exhibit a twofold difference in relative carbon flux from malate into lactate and alanine vs. alpha,alpha-trehalose compared to low ADH activity genotypes. Carbon 92-98 Alcohol dehydrogenase Drosophila melanogaster 38-41 7990980-2 1994 Symmetric cross-linkage at lysine B29 with a bridge of 2 (oxalyl), 8 (suberoyl) or 12 (dodecanedioyl) carbon atoms produced derivatives with essentially unaltered receptor binding affinity but largely reduced intrinsic activity. Carbon 102-108 CD79B antigen Mus musculus 34-37 7954901-7 1994 Its protein product is not strictly essential for mitochondrial functions, but disruption of the gene by insertion of LEU2 noticeably affected cellular growth on non-fermentable carbon sources. Carbon 178-184 3-isopropylmalate dehydrogenase Saccharomyces cerevisiae S288C 118-122 8027068-8 1994 Expression of APA1 gene is regulated by the carbon source and requires the protein GCR1. Carbon 44-50 bifunctional AP-4-A phosphorylase/ADP sulfurylase Saccharomyces cerevisiae S288C 14-18 7984550-0 1994 [Noncovalent immobilization of catalase on antibodies adsorbed on carbon fabric]. Carbon 66-72 catalase Homo sapiens 31-39 7984550-1 1994 Catalase was immobilized on an immunosorbent prepared by anticatalase adsorption on an activated carbon fabric (ACF), and its kinetic parameters were determined. Carbon 97-103 catalase Homo sapiens 0-8 8185321-2 1994 In the wild type yeast, the expression of both genes is influenced by both the growth phase and the type of carbon source, indicating discrete regulatory mechanisms and metabolic roles for PYC1 and PYC2. Carbon 108-114 pyruvate carboxylase 2 Saccharomyces cerevisiae S288C 198-202 8071385-8 1994 The presence of air at the water-carbon interface seems to prevent the surface denaturation of fibrinogen. Carbon 33-39 fibrinogen beta chain Homo sapiens 95-105 7986648-1 1994 Two new 2-D crystal forms of the Escherichia coli chaperone GroEL (cpn60) 2 x 7-mer have been produced using the negative staining-carbon film (NS-CF) technique. Carbon 131-137 GroEL Escherichia coli 60-65 10011433-0 1994 Electronic and transport properties of perfect sp2-bonded amorphous graphitic carbon. Carbon 78-84 Sp2 transcription factor Homo sapiens 47-50 7519559-3 1994 Neurotensin and substance P did not affect the value at concentrations less than 10(-7) M. The number of extravasated carbon particle deposits subsequent to tracheal application of neuropeptide Y during spontaneous respiration increased in a dose-dependent manner. Carbon 118-124 neuropeptide Y Rattus norvegicus 181-195 8283061-4 1994 When KS cells were incubated with poly (I:C) in combination with either IL-1 beta or TNF-alpha, there was a synergistic increase in the level of IL-6 production, whereas LPS and TNF-alpha in combination led to only an additive increase in the level of IL-6 production. Carbon 42-43 tumor necrosis factor Homo sapiens 85-94 8300563-5 1994 The purification of delta 3,5, delta 2,4-dienoyl-CoA isomerase completes the characterization of the enzymes functioning in the NADPH-dependent pathway for the beta-oxidation of unsaturated fatty acids with double bonds extending from odd-numbered carbon atoms. Carbon 248-254 delta like canonical Notch ligand 3 Rattus norvegicus 20-62 8283061-4 1994 When KS cells were incubated with poly (I:C) in combination with either IL-1 beta or TNF-alpha, there was a synergistic increase in the level of IL-6 production, whereas LPS and TNF-alpha in combination led to only an additive increase in the level of IL-6 production. Carbon 42-43 interleukin 6 Homo sapiens 145-149 8283061-4 1994 When KS cells were incubated with poly (I:C) in combination with either IL-1 beta or TNF-alpha, there was a synergistic increase in the level of IL-6 production, whereas LPS and TNF-alpha in combination led to only an additive increase in the level of IL-6 production. Carbon 42-43 tumor necrosis factor Homo sapiens 178-187 8283061-4 1994 When KS cells were incubated with poly (I:C) in combination with either IL-1 beta or TNF-alpha, there was a synergistic increase in the level of IL-6 production, whereas LPS and TNF-alpha in combination led to only an additive increase in the level of IL-6 production. Carbon 42-43 interleukin 6 Homo sapiens 252-256 8166954-6 1994 In addition the sensor had a 90-99% response time of 1 min when used at a flow rate of 3 ml min-1 and showed a temperature dependence of 2.4% C-1. Carbon 142-143 CD59 molecule (CD59 blood group) Homo sapiens 92-97 8226973-3 1993 When a cytochrome c1-deficient yeast strain was transformed with a plasmid encoding the fusion protein, the cells could not grow on nonfermentable carbon sources such as glycerol. Carbon 147-153 oogenesin 1 Mus musculus 18-20 8263321-1 1994 Recombinant human growth hormone was covalently linked to biotin via a six-carbon spacer arm. Carbon 75-81 growth hormone 1 Homo sapiens 18-32 7931241-8 1994 The competitive element of this inhibition (measured by Kis) was similar for the 2 and 3 carbon-chain compounds but decreased markedly when the chain-length was increased to 4 carbons. Carbon 89-95 U2AF homology motif kinase 1 Homo sapiens 56-59 7931241-8 1994 The competitive element of this inhibition (measured by Kis) was similar for the 2 and 3 carbon-chain compounds but decreased markedly when the chain-length was increased to 4 carbons. Carbon 176-183 U2AF homology motif kinase 1 Homo sapiens 56-59 8269928-2 1993 Comparable amounts of PDA1 mRNA and E1 alpha subunit were detected in cells from batch and chemostat cultures grown on various carbon sources, showing constitutive expression of PDA1 at the transcriptional and translational levels. Carbon 127-133 pyruvate dehydrogenase (acetyl-transferring) subunit E1 alpha Saccharomyces cerevisiae S288C 22-26 8131219-5 1994 This result is consistent with nucleophilic attack of the C-1 carbon of the UDP-glucuronic acid (UDPGA) by an SN2 mechanism. Carbon 62-68 solute carrier family 38 member 5 Homo sapiens 110-113 8264590-7 1994 DRS1, a pair of adjacent and opposing ABF1 sites (+288 to +313), is responsible for a 1.3- to 2-fold repression of transcription, depending on the carbon source. Carbon 147-153 DNA-binding protein ABF1 Saccharomyces cerevisiae S288C 38-42 8226984-6 1993 We found that growth on fermentable carbon sources, but not on gluconeogenic carbon sources, is reduced in cells disrupted for TKL1. Carbon 36-42 transketolase TKL1 Saccharomyces cerevisiae S288C 127-131 8226984-8 1993 Growth on fermentable carbon sources is also reduced in cells that overexpress TKL1. Carbon 22-28 transketolase TKL1 Saccharomyces cerevisiae S288C 79-83 8354690-4 1993 MAS6 encodes a 23-kD protein that contains several potential membrane spanning domains, and yeast strains disrupted for MAS6 are inviable at all temperatures and on all carbon sources. Carbon 169-175 protein transporter TIM23 Saccharomyces cerevisiae S288C 0-4 8399226-5 1993 Thus, we propose that the following two key structural features of the binding ligand are necessary for mimicking the thermodynamic effects natural substrate has on MCAD: a thioester carbonyl on carbon 1 and a fatty acyl-CoA chain length around 8 carbon units. Carbon 183-189 acyl-CoA dehydrogenase medium chain Homo sapiens 165-169 8399226-5 1993 Thus, we propose that the following two key structural features of the binding ligand are necessary for mimicking the thermodynamic effects natural substrate has on MCAD: a thioester carbonyl on carbon 1 and a fatty acyl-CoA chain length around 8 carbon units. Carbon 195-201 acyl-CoA dehydrogenase medium chain Homo sapiens 165-169 7690250-7 1993 Cyclosporin A in calphostin C-treated cells resulted in additive P-glycoprotein antagonism, while no additive effect could be demonstrated with verapamil, suggesting that the increase in verapamil transport makes it a poorer P-glycoprotein antagonist. Carbon 0-1 ATP binding cassette subfamily B member 1 Homo sapiens 65-79 7690250-7 1993 Cyclosporin A in calphostin C-treated cells resulted in additive P-glycoprotein antagonism, while no additive effect could be demonstrated with verapamil, suggesting that the increase in verapamil transport makes it a poorer P-glycoprotein antagonist. Carbon 0-1 ATP binding cassette subfamily B member 1 Homo sapiens 225-239 8220905-16 1993 In Ca2+-free Krebs bicarbonate solution, 100 nM ET-1 induced a significantly larger contraction than that induced by 100 nM sarafotoxin S6c (46.6 +/- 5.6% C,., versus 8.8 +/- 2.8% Cmax, n = 5-7). Carbon 3-4 endothelin 1 Rattus norvegicus 48-52 8366024-9 1993 The sequencing of gene STR4 has allowed us to compare all of the known sequences of transsulfuration enzymes and enzymes catalyzing the incorporation of reduced sulfur in carbon chains. Carbon 171-177 cystathionine beta-synthase CYS4 Saccharomyces cerevisiae S288C 23-27 8366037-1 1993 Growth and carbon metabolism in triosephosphate isomerase (delta tpi1) mutants of Saccharomyces cerevisiae are severely inhibited by glucose. Carbon 11-17 triose-phosphate isomerase TPI1 Saccharomyces cerevisiae S288C 65-69 7764348-4 1993 By using an inducible promoter to regulate the expression of FBA1 gene, we have also obtained the modulation of plasmid copy number by carbon source. Carbon 135-141 fructose-bisphosphate aldolase FBA1 Saccharomyces cerevisiae S288C 61-65 8370454-1 1993 Three-carbon compounds are substrates for sheep liver sorbitol dehydrogenase. Carbon 6-12 L-iditol 2-dehydrogenase Ovis aries 54-76 8354690-4 1993 MAS6 encodes a 23-kD protein that contains several potential membrane spanning domains, and yeast strains disrupted for MAS6 are inviable at all temperatures and on all carbon sources. Carbon 169-175 protein transporter TIM23 Saccharomyces cerevisiae S288C 120-124 8344434-1 1993 Mouse IgG1, IgG2a, and IgG2b proteins have been selectively labeled with 13C at the carbonyl carbon of His, Met, Trp or Tyr residue and used to prepare the corresponding Fc fragments by limited proteolysis. Carbon 84-90 immunoglobulin heavy constant gamma 1 (G1m marker) Mus musculus 6-10 8321194-4 1993 A second similar zinc finger gene, MSN4, was isolated, and deletion of both genes caused phenotypic defects related to carbon utilization. Carbon 119-125 stress-responsive transcriptional activator MSN4 Saccharomyces cerevisiae S288C 35-39 8341712-5 1993 The length, by alpha-carbon separation, of des-Glu84-CaM is 56 A; that of native CaM is 64 A. Carbon 21-27 calmodulin 1 Homo sapiens 53-56 8336735-2 1993 Here we report results concerning one of these mutants, rvs167, which shows reduced viability and abnormal cell morphology upon carbon and nitrogen starvation. Carbon 128-134 amphiphysin Saccharomyces cerevisiae S288C 56-62 17739800-5 1993 The results indicate that carbon grows first in linear chains, transforms to monocyclic planar rings at about C(10), and forms new families of planar bi-, tri-, and tetracyclic rings at C(20), C(30), and C(40), respectively. Carbon 26-32 homeobox C10 Homo sapiens 110-115 8506370-4 1993 In this II-DNA helix, the 5"-CGA trinucleotide is the structural motif that accounts for the stability, with the C+-C hemiprotonated base pair (in which C+ is N3-protonated cytosine) providing for the alignment site and the unusual interstrand G-A base stack in the GpA step furnishing the additional stabilizing forces. Carbon 113-115 chromogranin A Homo sapiens 29-32 8334074-1 1993 In rats with CCl4-induced liver cirrhosis, a twofold decrease of blood clearance rate and a fourfold reduction in number of Kupffer cells taking up colloidal carbon particles has been demonstrated. Carbon 158-164 C-C motif chemokine ligand 4 Rattus norvegicus 13-17 7683848-4 1993 Protein kinase C (PKC) is a signal-transducing enzyme that is an important regulator of postreceptor intracellular changes following exposure of platelets to thrombin and cathepsin G. Inhibitors of purified PKC, e.g., staurosporine and calphostin C, have been frequently used to elucidate biochemical mechanisms mediated by the intracellular PKC following platelet activation by proteases. Carbon 15-16 coagulation factor II, thrombin Homo sapiens 158-166 8501464-7 1993 Apparent distances between the heme iron of lactoperoxidase and either the carbon or nitrogen atoms of bound thiocyanate ion have been determined through application of the Solomon-Bloembergen equation. Carbon 75-81 lactoperoxidase Homo sapiens 44-59 8316042-1 1993 Most saturated diacyl phosphatidylcholines C(X):C(Y)PC (saturated 1,2-diacyl-sn-glycero-3-phosphocholine with X carbons in the sn-1 acyl chain and Y carbons in the sn-2 acyl chain), in excess water, can self-assemble into lamellae which, upon heating, may undergo multiple thermotropic phase transitions at well-defined, discrete temperatures. Carbon 112-119 solute carrier family 38 member 3 Homo sapiens 127-131 8316042-1 1993 Most saturated diacyl phosphatidylcholines C(X):C(Y)PC (saturated 1,2-diacyl-sn-glycero-3-phosphocholine with X carbons in the sn-1 acyl chain and Y carbons in the sn-2 acyl chain), in excess water, can self-assemble into lamellae which, upon heating, may undergo multiple thermotropic phase transitions at well-defined, discrete temperatures. Carbon 149-156 solute carrier family 38 member 3 Homo sapiens 127-131 8319713-1 1993 Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase (LCHAD), the third enzyme of the mitochondrial beta-oxidation pathway, carries out the dehydrogenation of 3-hydroxyacyl-CoA compounds of 12-18 carbon length. Carbon 193-199 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Homo sapiens 0-49 8319713-1 1993 Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase (LCHAD), the third enzyme of the mitochondrial beta-oxidation pathway, carries out the dehydrogenation of 3-hydroxyacyl-CoA compounds of 12-18 carbon length. Carbon 193-199 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Homo sapiens 51-56 8455597-3 1993 All of the cot2 mutants exhibited a wiener-shaped cellular morphology that was exacerbated by the carbon and nitrogen source but was unaffected by metals. Carbon 98-104 SCF ubiquitin ligase complex subunit GRR1 Saccharomyces cerevisiae S288C 11-15 8457559-4 1993 On the other hand, a linker of at least 13 carbon atoms is required for full competitive inhibition of the hydrolysis by thrombin of small synthetic substrates, which only bind to the catalytic pocket of the enzyme. Carbon 43-49 coagulation factor II, thrombin Homo sapiens 121-129 8509668-6 1993 Amniotic fluid concentrations of TNF-alpha, IL-1 beta and IL-6 in cases of term elective C/S were 22.8 +/- 19.2 pg/ml, 8.1 +/- 5.2 pg/ml and 166.8 +/- 126.1 pg/ml, respectively. Carbon 89-90 tumor necrosis factor Homo sapiens 33-42 8509668-6 1993 Amniotic fluid concentrations of TNF-alpha, IL-1 beta and IL-6 in cases of term elective C/S were 22.8 +/- 19.2 pg/ml, 8.1 +/- 5.2 pg/ml and 166.8 +/- 126.1 pg/ml, respectively. Carbon 89-90 interleukin 6 Homo sapiens 58-62 8468121-0 1993 Enhancement of various non-specific immune effector functions in mice by local injection of aclacinomycin A adsorbed onto activated carbon particles (ACR-CH). Carbon 132-138 acrosin prepropeptide Mus musculus 150-153 8511964-3 1993 Transfer of ammonium-glucose pre-grown cells to a medium deprived of nitrogen causes a drastic increase in CPS1 RNA level provided that a readily usable carbon source, such as glucose or fructose, is available to the cells. Carbon 153-159 Gly-Xaa carboxypeptidase Saccharomyces cerevisiae S288C 107-111 8459402-8 1993 A decrease in activity was observed with increasing length of the alkyl chain bonded to the C-10 position, but potency was less affected when the alkyl groups were positioned in close proximity to the C-10 carbon of the tropone ring. Carbon 206-212 homeobox C10 Homo sapiens 201-205 8444887-10 1993 These results demonstrate that fatty acyl groups one carbon longer or shorter than myristate can be accommodated within the membrane binding site for pp60v-src and illustrate the utility of in vitro systems for predicting analog behavior in vivo. Carbon 53-59 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 156-159 8468121-1 1993 Local injections of aclacinomycin A adsorbed onto activated carbon particles (ACR-CH) augmented the cytotoxic activities of regional lymph node cells for 7 days. Carbon 60-66 acrosin prepropeptide Mus musculus 78-81 8473916-3 1993 These structures are composed entirely of sp3 carbons which are grown sequentially, but which can also branch or form rings. Carbon 46-53 Sp3 transcription factor Homo sapiens 42-45 8454567-5 1993 The upfield shift of 2-13C of MCAD relative to that of FMN in the aqueous medium and its downfield shift relative to that of tetraacetylriboflavin in an apolar medium imply that a weaker hydrogen bond exists between C(2) = O and apoMCAD or a water molecule than that of free FMN with a water molecule. Carbon 25-26 acyl-CoA dehydrogenase medium chain Homo sapiens 30-34 8397147-6 1993 Further experiments demonstrate that the reverse process can also occur: when hydroxyl radicals react with BSA, the thiol group appears to act as a radical sink and protects the protein from denaturation and fragmentation through the transfer of damage from a carbon site to the thiol group. Carbon 260-266 albumin Homo sapiens 107-110 1334093-3 1992 ESR spin trapping using 5,5-dimethyl-1-pyrroline N-oxide showed that free .OH was indeed generated in the reaction of Cu,Zn-SOD/H2O2; this was substantiated by the almost complete eradication of .OH by either ethanol or dimethyl sulfoxide accompanied by the generation of carbon-centered radicals. Carbon 272-278 superoxide dismutase 1 Homo sapiens 124-127 8446054-8 1993 IL-1 alpha significantly increased concentrations of plasma insulin and the percentage of glucose carbon recycling, confirming previous findings. Carbon 98-104 interleukin 1 alpha Rattus norvegicus 0-10 8382892-2 1993 Deletion of QCR9 results in the inability of cells to grow on grow on-fermentable carbon sources at 37 degrees C. Thus, qcr9 mutants can be scored by growing cells on YPE/G at 37 degrees C, or followed by the URA3 marker, which was inserted when making the qcr9 deletion strain, JDP1. Carbon 82-88 ubiquinol--cytochrome-c reductase subunit 9 Saccharomyces cerevisiae S288C 12-16 1445903-5 1992 The NMR line shapes are roughly consistent with the results of previous FTIR and NMR studies that indicate the sn-1 chain extends from the C1 carbon of the glycerol backbone into the hydrophobic interior of the bilayer, while the sn-2 chain first extends parallel to the bilayer surface and incorporates a bend at the ester linkage in order to keep the sn-1 and sn-2 chains parallel. Carbon 142-148 solute carrier family 38 member 3 Homo sapiens 111-115 1487725-1 1992 Secretion of the extracellular Rhizopus carboxyl proteinase (EC 3.4.23.6) by Rhizopus oligosporus is repressed in the presence of low-molecular-mass sources of nitrogen, sulphur and carbon. Carbon 182-188 endogenous retrovirus group K member 25 Homo sapiens 49-59 1447211-6 1992 Levels of MDH3 were determined to be elevated in cells grown with acetate as a carbon source, and under these conditions, MDH3 contributed approximately 10% of the total cellular malate dehydrogenase activity. Carbon 79-85 malate dehydrogenase MDH3 Saccharomyces cerevisiae S288C 10-14 1493607-11 1992 The results rather suggest that cytochrome P-450 catalyzed aromatic hydroxylation of monofluoroanilines proceeds by an electrophilic attack of the (FeO)3+ species of cytochrome P-450 on a specific carbon atom of the aromatic aniline-ring. Carbon 197-203 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 32-48 1493607-11 1992 The results rather suggest that cytochrome P-450 catalyzed aromatic hydroxylation of monofluoroanilines proceeds by an electrophilic attack of the (FeO)3+ species of cytochrome P-450 on a specific carbon atom of the aromatic aniline-ring. Carbon 197-203 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 166-182 1332881-1 1992 Deletion of QCR9, the nuclear gene encoding subunit 9 of the mitochondrial cytochrome bc1 complex in Saccharomyces cerevisiae, results in inactivation of the bc1 complex and inability of the yeast to grow on non-fermentable carbon sources. Carbon 224-230 ubiquinol--cytochrome-c reductase subunit 9 Saccharomyces cerevisiae S288C 12-16 1390933-0 1992 Lactoperoxidase-catalyzed oxidation of thiocyanate ion: a carbon-13 nuclear magnetic resonance study of the oxidation products. Carbon 58-64 lactoperoxidase Homo sapiens 0-15 1446003-2 1992 The principal product is the 5"-carbon atom oxidation product, nicotine delta 1",5"-iminium ion, which is efficiently converted to the gamma-lactam derivative cotinine in the presence of aldehyde oxidase. Carbon 32-38 aldehyde oxidase 1 Homo sapiens 187-203 1400383-11 1992 The results of this study suggest that adult chick corneas contain two isoforms of decorin: one containing C/DS side chains and the other, a hybrid, containing both C/DS and KS side chains. Carbon 107-108 decorin Gallus gallus 83-90 1400383-11 1992 The results of this study suggest that adult chick corneas contain two isoforms of decorin: one containing C/DS side chains and the other, a hybrid, containing both C/DS and KS side chains. Carbon 165-166 decorin Gallus gallus 83-90 1433183-7 1992 Inhibitors with relatively short carbon chain lengths (i.e. four to six carbons) were found to be more potent than those with longer chains in inhibiting brain MAO-B activity in vivo especially after oral administration. Carbon 33-39 monoamine oxidase B Mus musculus 160-165 1433183-7 1992 Inhibitors with relatively short carbon chain lengths (i.e. four to six carbons) were found to be more potent than those with longer chains in inhibiting brain MAO-B activity in vivo especially after oral administration. Carbon 72-79 monoamine oxidase B Mus musculus 160-165 1330423-11 1992 The production of IFN was readily stimulated with Poly I:C. Carbon 57-58 interferon alpha 1 Homo sapiens 18-21 1644826-11 1992 Growth phenotype analysis of the IDH1 disruption strains revealed that they grew at a reduced rate on the nonfermentable carbon sources examined (glycerol, lactate, and acetate), consistent with NAD(+)-dependent isocitrate dehydrogenase performing a critical role in oxidative function of the citric acid cycle. Carbon 121-127 isocitrate dehydrogenase (NAD(+)) IDH1 Saccharomyces cerevisiae S288C 33-37 1499856-6 1992 We conclude that intraportal administration of insulin via the umbilical vein at rates of 0.01-0.05 U.kg-1.hr-1 reduces plasma levels of glucose, three carbon precursors, cortisol, and growth hormone by a direct action on the liver, and the hepatic action of peripherally administered insulin is manifested only when the infusion rate is increased to 0.1-0.3 U.kg-1.hr-1. Carbon 152-158 insulin Homo sapiens 47-54 1398065-4 1992 We show that MAK10 is essential for optimal growth on nonfermentable carbon sources independent of its effect on L-A. Carbon 69-75 Mak10p Saccharomyces cerevisiae S288C 13-18 1324416-0 1992 ABF1 is a phosphoprotein and plays a role in carbon source control of COX6 transcription in Saccharomyces cerevisiae. Carbon 45-51 DNA-binding protein ABF1 Saccharomyces cerevisiae S288C 0-4 1324416-13 1992 This carbon source regulation is exerted through domain 1, a region of the upstream activation sequence UAS6 that binds ABF1 (J. D. Trawick, N. Kraut, F. Simon, and R. O. Poyton, Mol. Carbon 5-11 DNA-binding protein ABF1 Saccharomyces cerevisiae S288C 120-124 1324416-17 1992 Furthermore, the ABF1-containing protein-DNA complexes formed at domain 1 differ according to the phosphorylation state of ABF1 and the carbon source on which the cells were grown. Carbon 136-142 DNA-binding protein ABF1 Saccharomyces cerevisiae S288C 17-21 1434786-1 1992 The effect of local tissue injection of activated carbon particle adsorbing aclacinomycin A (ACR-CH) on the cytotoxicity in popliteal, inguinal, paraaortic, and axillary lymph nodes was investigated in mice. Carbon 50-56 acrosin prepropeptide Mus musculus 93-96 1377774-7 1992 The PMI40 gene is located on chromosome V, and its transcription is increased 12-fold when cells are grown on D-mannose as sole carbon source instead of D-glucose. Carbon 128-134 mannose-6-phosphate isomerase PMI40 Saccharomyces cerevisiae S288C 4-9 1600837-4 1992 Stimulation of PDH by DCA increases peripheral oxidation of alanine and lactate, thereby interrupting the Cori and alanine cycles and reducing the availability of three-carbon precursors for gluconeogenesis. Carbon 169-175 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 15-18 1394683-4 1992 The in vitro ACE inhibitory activity of these compounds greatly depended on the configurations of the three asymmetric carbons in each molecule. Carbon 119-126 angiotensin I converting enzyme Homo sapiens 13-16 1314953-12 1992 Gel mobility shift experiments show that domain 1 binds ABF1 and forms different numbers of DNA-protein complexes in extracts from cells grown in repressing or derepressing carbon sources. Carbon 173-179 DNA-binding protein ABF1 Saccharomyces cerevisiae S288C 56-60 1378790-4 1992 In contrast to strains with an intact or a disrupted BMH1 gene, strains with the BMH1 gene on multicopy plasmids hardly grew on media with acetate or glycerol as carbon source. Carbon 162-168 14-3-3 family protein BMH1 Saccharomyces cerevisiae S288C 81-85 1314953-14 1992 Together, these findings permit the following conclusions: COX6 transcription is regulated both positively and negatively; heme and carbon source exert their effects through different sites; domain 1 is absolutely essential for transcription on repressing carbon sources; ABF1 is a major component in the regulation of COX6 transcription; and the HAP2/3/4 complex most likely affects COX6 transcription indirectly. Carbon 132-138 DNA-binding protein ABF1 Saccharomyces cerevisiae S288C 272-276 1314953-14 1992 Together, these findings permit the following conclusions: COX6 transcription is regulated both positively and negatively; heme and carbon source exert their effects through different sites; domain 1 is absolutely essential for transcription on repressing carbon sources; ABF1 is a major component in the regulation of COX6 transcription; and the HAP2/3/4 complex most likely affects COX6 transcription indirectly. Carbon 256-262 DNA-binding protein ABF1 Saccharomyces cerevisiae S288C 272-276 1298445-0 1992 Adsorption of bovine serum albumin onto glassy carbon in a Couette flow. Carbon 47-53 albumin Homo sapiens 21-34 16668864-8 1992 The activity of carbonic anhydrase, which provides PEP carboxylase with C(i), was determined by saturation transfer (13)C-NMR to be more than 200 times that of PEP carboxylase in vivo. Carbon 72-73 phosphoenolpyruvate carboxylase 2 Zea mays 51-54 16668864-8 1992 The activity of carbonic anhydrase, which provides PEP carboxylase with C(i), was determined by saturation transfer (13)C-NMR to be more than 200 times that of PEP carboxylase in vivo. Carbon 72-73 phosphoenolpyruvate carboxylase 2 Zea mays 160-163 1567907-4 1992 From the behavior of pKi dependence on the carbon number of the alcohol, the decyl group appears to be optimum to bind to L-1. Carbon 43-49 seed linoleate 13S-lipoxygenase-1 Glycine max 122-125 1420456-2 1992 The C-17 dithioketal moiety of the corticosteroid tipredane (INN, I) has been shown to undergo peroxide oxidation yielding an array of sulphoxide epimers. Carbon 4-5 growth hormone releasing hormone Homo sapiens 61-64 1298445-2 1992 Adsorption of bovine serum albumin onto glassy carbon is investigated by analysing the time-variation of the double-layer capacitance recorded during the adsorption process. Carbon 47-53 albumin Homo sapiens 21-34 1542055-8 1992 The energetic efficiencies by which propionate and lactate carbon are converted to glucose may be much less than optimal because of extensive cycling through pyruvate kinase, pyruvate carboxylase and phosphoenolpyruvate carboxykinase. Carbon 59-65 pyruvate carboxylase Homo sapiens 175-195 1545789-2 1992 Mutational analysis of these sites suggests that ABF1 is involved in constitutive and carbon source-regulated transcriptional activation, transcriptional silencing, and ARS activity. Carbon 86-92 DNA-binding protein ABF1 Saccharomyces cerevisiae S288C 49-53 1317470-3 1992 At the onset of ischemia a significant increase in the level of MDA plasma concentrations and significant decreases in both SOD blood concentrations and the SOD-inhibitable reduction of ferricytochrome C indicated oxygen free radicals had been released in the SAP patients. Carbon 202-203 superoxide dismutase 1 Homo sapiens 157-160 1542684-1 1992 Nitrate reductase, the first enzyme in nitrate assimilation, is located at the crossroad of two energy-consuming pathways: nitrate assimilation and carbon fixation. Carbon 148-154 nitrate reductase 1 Arabidopsis thaliana 0-17 1627833-8 1992 In contrast to ionomycin, incubation of IFN-primed macrophages with poly [I:C] did not sustain measurable increases in [Ca2+]i, yet fully stimulated the transition from the IFN primed to the cytocidal state. Carbon 76-77 interferon alpha 1 Homo sapiens 40-43 1627833-8 1992 In contrast to ionomycin, incubation of IFN-primed macrophages with poly [I:C] did not sustain measurable increases in [Ca2+]i, yet fully stimulated the transition from the IFN primed to the cytocidal state. Carbon 76-77 interferon alpha 1 Homo sapiens 173-176 1542684-2 1992 Light, which regulates the expression of many higher-plant carbon fixation genes, also regulates nitrate reductase gene expression. Carbon 59-65 nitrate reductase 1 Arabidopsis thaliana 97-114 1552849-7 1992 We have found that UCP expressed in S. cerevisiae is targeted to mitochondria and that its expression induces a marked growth defect on non-fermentable carbon sources in a manner dependent on induction with galactose. Carbon 152-158 uncoupling protein 1 Rattus norvegicus 19-22 1564445-5 1992 DNA sequencing showed that FUP1 encodes a hydrophilic 43 kDa protein identical to MSN1, a gene encoding a transcriptional activator implicated in carbon source regulation. Carbon 146-152 Msn1p Saccharomyces cerevisiae S288C 27-31 1733503-6 1992 IMF-1 is an acidic, amphiphilic molecule of Mr340 +/- 16 that does not contain ester, phosphate, amide, sialic acid, or glycosidic or vicinal hydroxyl functionalities, but does contain a carbon-carbon double bond. Carbon 187-193 platelet derived growth factor receptor beta Homo sapiens 0-5 1733503-6 1992 IMF-1 is an acidic, amphiphilic molecule of Mr340 +/- 16 that does not contain ester, phosphate, amide, sialic acid, or glycosidic or vicinal hydroxyl functionalities, but does contain a carbon-carbon double bond. Carbon 194-200 platelet derived growth factor receptor beta Homo sapiens 0-5 1662603-3 1991 The IFN-gamma analogue proteins were shortened by 10 (C-10L), 11 (C-11, C-11L), 14 (C-14L), 19 (C-19L) and 20 (C-20) amino acid. Carbon 54-55 interferon gamma Homo sapiens 4-13 1545708-3 1992 Comparison of the beta-galactosidase activities of each strain during growth on glucose or ethanol revealed that some part of the LPD1 coding region between +13 and +700 is involved in activating gene expression in a carbon source-dependent manner. Carbon 217-223 dihydrolipoyl dehydrogenase Saccharomyces cerevisiae S288C 130-134 1545708-5 1992 Therefore, the LPD1 gene appears to contain a transcriptional enhancer that lies 3" to the transcriptional start site, and which responds to carbon source. Carbon 141-147 dihydrolipoyl dehydrogenase Saccharomyces cerevisiae S288C 15-19 1337538-2 1992 Cytochrome c was immobilised covalently at a surface-modified gold electrode and by passive adsorption to novel platinised activated carbon electrodes (PACE). Carbon 133-139 cytochrome c, somatic Homo sapiens 0-12 1559663-3 1992 It has been thought that NPH-C dissolve in the injected site by splitting of crystals into protamine and insulin. Carbon 29-30 insulin Homo sapiens 105-112 1662603-3 1991 The IFN-gamma analogue proteins were shortened by 10 (C-10L), 11 (C-11, C-11L), 14 (C-14L), 19 (C-19L) and 20 (C-20) amino acid. Carbon 66-67 interferon gamma Homo sapiens 4-13 1662603-3 1991 The IFN-gamma analogue proteins were shortened by 10 (C-10L), 11 (C-11, C-11L), 14 (C-14L), 19 (C-19L) and 20 (C-20) amino acid. Carbon 66-67 interferon gamma Homo sapiens 4-13 1662603-3 1991 The IFN-gamma analogue proteins were shortened by 10 (C-10L), 11 (C-11, C-11L), 14 (C-14L), 19 (C-19L) and 20 (C-20) amino acid. Carbon 66-67 interferon gamma Homo sapiens 4-13 1662603-3 1991 The IFN-gamma analogue proteins were shortened by 10 (C-10L), 11 (C-11, C-11L), 14 (C-14L), 19 (C-19L) and 20 (C-20) amino acid. Carbon 66-67 interferon gamma Homo sapiens 4-13 1662603-5 1991 The expression rates of precipitating IFN-gamma variants in E. coli cells (wild type, C-10L, C-11, C-11L) amount to 35-40% of the total protein, in contrast to 14-21% for the mainly soluble ones (C-14L, C-20). Carbon 86-87 interferon gamma Homo sapiens 38-47 1662603-5 1991 The expression rates of precipitating IFN-gamma variants in E. coli cells (wild type, C-10L, C-11, C-11L) amount to 35-40% of the total protein, in contrast to 14-21% for the mainly soluble ones (C-14L, C-20). Carbon 93-94 interferon gamma Homo sapiens 38-47 1662603-5 1991 The expression rates of precipitating IFN-gamma variants in E. coli cells (wild type, C-10L, C-11, C-11L) amount to 35-40% of the total protein, in contrast to 14-21% for the mainly soluble ones (C-14L, C-20). Carbon 93-94 interferon gamma Homo sapiens 38-47 1932127-1 1991 Carnitine acetyltransferase (CAT) catalyzes the reversible transfer of short chain (less than six carbons in length) acyl groups from acyl-CoA thioesters to form the corresponding acylcarnitines. Carbon 98-105 carnitine O-acetyltransferase Rattus norvegicus 0-27 1939174-5 1991 Carbon fluxes deduced from these enrichment patterns were correlated with the in vitro alcohol dehydrogenase activities in three different Adh genotypes in seven different strains. Carbon 0-6 Alcohol dehydrogenase Drosophila melanogaster 87-108 1803997-6 1991 The crystallographic parameters for (+/-)-mefloquine methylsulfonate monohydrate were as follows: C17H17F6N2O(+).CH3SO3(-).H2O; Mr = 492.4; symmetry of unit cell, monoclinic; space group, P2(1)/a; parameters of unit cell, a was 8.678 +/- 0.001 A, b was 28.330 +/- 0.003 A, c was 8.804 +/- 0.001 A, beta was 97.50 +/- 0.01 degrees; the volume of the unit cell was 2145.9 A3; the number of molecules per unit cell was 4; the calculated density was 1.52 g cm(-3); the source of radiation was Cu K alpha (lambda = 1.54178 A); mu (absorption coefficient) was 20.46 cm(-1); F(000) (sum of atomic scattering factors at zero scattering angle) was 1,016; room temperature was used; and the final R (residual index) was 6.58% for 1,740 reflections with magnitude of Fo greater than 3 sigma (F). Carbon 4-5 cyclin dependent kinase inhibitor 1A Homo sapiens 188-193 1940805-8 1991 VPF protein staining was evident in adjacent preexisting venules and small veins as early as 5 h after tumor transplant and plateaued at maximally intense levels in newly induced tumor vessels by approximately 5 d. VPF-stained vessels were also hyperpermeable to macromolecules as judged by their capacity to accumulate circulating colloidal carbon. Carbon 342-348 vascular endothelial growth factor A Homo sapiens 0-3 1940805-8 1991 VPF protein staining was evident in adjacent preexisting venules and small veins as early as 5 h after tumor transplant and plateaued at maximally intense levels in newly induced tumor vessels by approximately 5 d. VPF-stained vessels were also hyperpermeable to macromolecules as judged by their capacity to accumulate circulating colloidal carbon. Carbon 342-348 vascular endothelial growth factor A Homo sapiens 215-218 9999347-0 1991 Structural properties of sp3-bonded hydrogenated amorphous carbon. Carbon 59-65 Sp3 transcription factor Homo sapiens 25-28 1944593-1 1991 The three mammalian lipoxygenases are named according to the carbon position (5, 12 or 15) at which they catalyse the oxygenation of arachidonic acid; they are implicated in inflammatory disorders, for example 15-lipoxygenase is induced in atherosclerosis and can oxidize low-density lipoprotein to its atherogenic form. Carbon 61-67 arachidonate 15-lipoxygenase Homo sapiens 210-225 1944593-4 1991 This effect can be mimicked by incubating wild-type 15-lipoxygenase with a synthetically altered substrate which has its doubly allylic methylene carbons shifted by one carbon relative to arachidonic acid. Carbon 146-153 arachidonate 15-lipoxygenase Homo sapiens 52-67 1944593-4 1991 This effect can be mimicked by incubating wild-type 15-lipoxygenase with a synthetically altered substrate which has its doubly allylic methylene carbons shifted by one carbon relative to arachidonic acid. Carbon 146-152 arachidonate 15-lipoxygenase Homo sapiens 52-67 1932127-1 1991 Carnitine acetyltransferase (CAT) catalyzes the reversible transfer of short chain (less than six carbons in length) acyl groups from acyl-CoA thioesters to form the corresponding acylcarnitines. Carbon 98-105 carnitine O-acetyltransferase Rattus norvegicus 29-32 1751793-3 1991 In this report, a method of characterizing C5a receptors by using a novel probe consisting of C5a attached to biotin via a six-carbon spacer chain is described. Carbon 127-133 complement C5a receptor 1 Homo sapiens 43-46 11538087-1 1991 We have detected a new carbon-chain molecule, CCO(3 sigma-), in the cold, dark molecular cloud TMC-1. Carbon 23-29 transmembrane channel like 1 Homo sapiens 95-100 33874131-11 1991 Using EPI with a ray-tracing technique to determine the PPFD index and taking into account respiration and carbon incorporated structurally, maximal productivity of CAM plants is predicted to occur at leaf or stem area indices of 4-5. Carbon 107-113 calmodulin 3 Homo sapiens 165-168 1761525-1 1991 The indole C-2(delta 1) carbon of Trp 62 in hen egg-white lysozyme was selectively labeled with 13C through a series of reactions involving N"-formylkynurenine 62-lysozyme with K13CN, NaBH4-reduction, and acid-catalyzed dehydration. Carbon 24-30 delta like non-canonical Notch ligand 1 Homo sapiens 11-22 1910150-5 1991 kns1 mutants grow at the same rate as wild-type cells using several different carbon sources. Carbon 78-84 serine/threonine protein kinase KNS1 Saccharomyces cerevisiae S288C 0-4 1892890-10 1991 These results show that non-esterified fatty acids can modulate the CETP-mediated transfer of cholesteryl esters from HDL to LDL and that this effect is dependent on both the length and the degree of unsaturation of their monomeric carbon chain. Carbon 232-238 cholesteryl ester transfer protein Homo sapiens 68-72 1856865-1 1991 The resulting atomic co-ordinates indicate that the NAM residue in site D is distorted from the full 4C1 chair conformation to one in which the ring atoms C-1, C-2, O-5 and C-5 are approximately coplanar, and the hydroxymethyl group is positioned axially (a conformation best described as a sofa). Carbon 102-103 SH3 and cysteine rich domain 3 Homo sapiens 52-55 1854738-4 1991 A large [14C]carbonyl carbon isotope effect of 1.12 +/- 0.02 was measured for the cobra venom PLA2-catalyzed hydrolysis of dipalmitoylphosphatidylcholine in Triton X-100. Carbon 13-19 phospholipase A2 group IB Homo sapiens 94-98 1856865-1 1991 The resulting atomic co-ordinates indicate that the NAM residue in site D is distorted from the full 4C1 chair conformation to one in which the ring atoms C-1, C-2, O-5 and C-5 are approximately coplanar, and the hydroxymethyl group is positioned axially (a conformation best described as a sofa). Carbon 155-156 SH3 and cysteine rich domain 3 Homo sapiens 52-55 1929298-1 1991 We describe a novel nucleoside analog, 2"-deoxy-3"-thiacytidine (BCH-189), in which the 3" carbon of the ribose ring of 2"-deoxycytidine has been replaced by a sulfur atom. Carbon 91-97 chimerin 2 Homo sapiens 65-68 2043623-1 1991 The glycolytic enzyme triosephosphate isomerase (TIM) catalyzes the interconversion of the three-carbon sugars dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde 3-phosphate (GAP) at a rate limited by the diffusion of substrate to the enzyme. Carbon 97-103 triosephosphate isomerase 1 Homo sapiens 49-52 1854897-3 1991 All the carbon environments of the poly(orthoesters) are detected within the high-resolution C1s peak envelopes and again, good agreement is observed between the theoretical and experimental proportions of each carbon environment. Carbon 8-14 complement C1s Homo sapiens 93-96 1903399-7 1991 Gel permeation chromatography of radiolabeled hydrocarbons released from the rac1, rac2, and ralA proteins by reaction with Raney nickel catalyst indicated that unlike p21Hras, which was modified by a 15-carbon moiety, the rac and ralA translation products were modified by 20-carbon isoprenyl groups. Carbon 51-57 Rac family small GTPase 2 Homo sapiens 83-87 1911530-3 1991 In view of the physiological importance of ornithine and putrescine, we now investigated whether interferon-gamma (IFN-gamma), a principal stimulator of the OAD activity, may lead to the accumulation of the deiminated derivative citrulline at the expense of ornithine production, or whether the carbon backbone could be reutilized for the production of arginine and ornithine. Carbon 295-301 interferon gamma Mus musculus 97-113 1911530-3 1991 In view of the physiological importance of ornithine and putrescine, we now investigated whether interferon-gamma (IFN-gamma), a principal stimulator of the OAD activity, may lead to the accumulation of the deiminated derivative citrulline at the expense of ornithine production, or whether the carbon backbone could be reutilized for the production of arginine and ornithine. Carbon 295-301 interferon gamma Mus musculus 115-124 1849735-2 1991 The reduction of horse heart ferricytochrome c by the tryptic fragment of bovine liver cytochrome b5 and its dimethyl ester heme (DME)-substituted derivative has been studied as a function of ionic strength, pH, and temperature under solution conditions where the reaction is bimolecular. Carbon 8-9 cytochrome b5 type A Bos taurus 87-100 1678255-0 1991 In vivo voltammetric detection of neuropeptides with micro carbon fiber biosensors: possible selective detection of somatostatin. Carbon 59-65 somatostatin Rattus norvegicus 116-128 1893492-5 1991 SPR-901 showed significant antitumor activities against murine allogeneic and syngeneic tumors by both intraperitoneal and oral administration, and enhanced carbon clearance ability in mice, while it showed no direct cytotoxicities in vitro. Carbon 157-163 sepiapterin reductase Mus musculus 0-3 1715498-3 1991 The administration of neurotensin (1 or 3 micrograms/microliters) into the nucleus accumbens adjacent to the carbon fibre electrode produced a decrease in the extracellular 3,4-dihydroxyphenylacetic acid peak. Carbon 109-115 neurotensin Homo sapiens 22-33 2017142-8 1991 In rho+ cells, the transcription of the YMR26 gene was more repressed in a medium with glucose than in the presence of either galactose or nonfermentable carbon sources. Carbon 154-160 mitochondrial 54S ribosomal protein YmL25 Saccharomyces cerevisiae S288C 40-45 1868114-3 1991 The proteins and PL were acylated with succinylSMX succinimido ester, affording conjugates (succinylSMX)2-21-HSA, (succinylSMX)17,27-TR, (succinylSMX)11-Lys16, and (succinylSMX)71-Lys430 in which SMX was linked by a spacer chain of four carbons. Carbon 237-244 transferrin Homo sapiens 133-135 2127555-6 1990 S. cerevisiae cells transformed with a plasmid, pRD1, containing both the xylose reductase gene (XYL1) and the xylitol dehydrogenase gene (XYL2), were able to grow on xylose as a sole carbon source. Carbon 184-190 metalloendopeptidase Saccharomyces cerevisiae S288C 48-52 1990439-1 1991 Rotationally resonant magnetization exchange, a new nuclear magnetic resonance (NMR) technique for measuring internuclear distances between like spins in solids, was used to determine the distance between the C-8 and C-18 carbons of retinal in two model compounds and in the membrane protein bacteriorhodopsin. Carbon 222-229 Bardet-Biedl syndrome 9 Homo sapiens 217-221 1984343-3 1991 Results showed that basal leucine carbon flux was greater (P less than 0.05) in UB Ob and LB Ob women than in Non Ob women (2.96 +/- 0.08 vs 3.14 +/- 0.16 vs 2.68 +/- 0.08 mumol.kg lean body mass-1.min-1, respectively; mean +/- SEM). Carbon 34-40 adhesion G protein-coupled receptor V1 Homo sapiens 191-197 1984343-3 1991 Results showed that basal leucine carbon flux was greater (P less than 0.05) in UB Ob and LB Ob women than in Non Ob women (2.96 +/- 0.08 vs 3.14 +/- 0.16 vs 2.68 +/- 0.08 mumol.kg lean body mass-1.min-1, respectively; mean +/- SEM). Carbon 34-40 CD59 molecule (CD59 blood group) Homo sapiens 198-203 1991481-7 1991 The 13C-NMR data also show that the carbon efflux through phosphoenolpyruvate carboxykinase increases from 0.35 to 0.56 in rat renal PCT cells derived from chronic acidotic animals, as well as in the presence of angiotensin II. Carbon 36-42 angiotensinogen Rattus norvegicus 212-226 2124139-3 1990 This finding provides strong evidence for a regioselective oxidative attack by cytochrome P-450-dependent monooxygenase with preferential insertion of oxygen at meta-para unsubstituted carbon atoms. Carbon 185-191 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 79-95 1963809-3 1990 On the other hand, the heterologous promoter of the Saccharomyces cerevisiae alcohol dehydrogenase I gene (adc1) is shown to be a weak promoter in Schizosaccharomyces pombe, though its activity is significantly enhanced in cells grown on glycerol as a carbon source. Carbon 252-258 alcohol dehydrogenase ADH1 Saccharomyces cerevisiae S288C 107-111 1988440-7 1991 For the 6-carbon link the Gibbs free energy of unfolding was 8.0 kcal/mol compared to 4.5 kcal/mol for insulin, and the amide exchange rate decreased by at least 3-fold. Carbon 10-16 insulin Homo sapiens 103-110 1988440-8 1991 A very short cross-link (i.e. the 2-carbon link) caused conformational strain that was detectable by a lack of stabilization in the Gibbs free energy of unfolding and enhancement in the amide exchange rate compared to insulin. Carbon 36-42 insulin Homo sapiens 218-225 1863522-8 1991 Thus, the configuration of the benzylic carbon bearing the hydroxyl group determined whether these benzylic alcohols were substrates or inhibitors of the rat hepatic aryl sulfotransferase IV. Carbon 40-46 sulfotransferase family 1A member 1 Rattus norvegicus 166-190 1676138-3 1991 Somatostatin-like peaks were measured every 6 min for 3 h by a carbon fiber electrode implanted in the proximity of the injection needle. Carbon 63-69 somatostatin Rattus norvegicus 0-12 2272921-3 1990 Intraperitoneal administration to murine tumors indicated that the effective dose ranges of the compounds having sp3 carbon at C-13 position were broader than those of the compounds having sp2 carbon. Carbon 193-199 Sp2 transcription factor Mus musculus 189-192 2125590-0 1990 Duramycins B and C, two new lanthionine containing antibiotics as inhibitors of phospholipase A2. Carbon 17-18 phospholipase A2 group IB Homo sapiens 80-96 2170531-5 1990 Pretreatment of neutrophils with either GM-CSF or TNF-alpha dose-dependently enhanced the production of superoxide induced by NaF, as determined by the superoxide dismutase-inhibitable reduction of ferricytochrome c. Carbon 82-83 tumor necrosis factor Homo sapiens 50-59 2170531-5 1990 Pretreatment of neutrophils with either GM-CSF or TNF-alpha dose-dependently enhanced the production of superoxide induced by NaF, as determined by the superoxide dismutase-inhibitable reduction of ferricytochrome c. Carbon 82-83 C-X-C motif chemokine ligand 8 Homo sapiens 126-129 2128175-7 1990 The observation that dietary carbohydrates and ethanol increase Gpdh expression without affecting expression of Ald and Pgk reinforces previous suggestions that dietary carbon can be diverted by GPDH from glycolytic catabolism into lipid biosynthesis. Carbon 169-175 Glycerol-3-phosphate dehydrogenase 1 Drosophila melanogaster 64-68 2085676-4 1990 Changes to the progesterone structure at C-17, C-20, or C-21 interfered with binding. Carbon 0-1 TBL1X/Y related 1 Homo sapiens 56-60 2128175-7 1990 The observation that dietary carbohydrates and ethanol increase Gpdh expression without affecting expression of Ald and Pgk reinforces previous suggestions that dietary carbon can be diverted by GPDH from glycolytic catabolism into lipid biosynthesis. Carbon 169-175 Glycerol-3-phosphate dehydrogenase 1 Drosophila melanogaster 195-199 2170848-4 1990 Haploid cells carrying a disrupted MIR1 allele were unable to grow on a non-fermentable carbon source but grew in media containing glucose, indicating that the MIR1 protein is essential for mitochondrial function. Carbon 88-94 Mir1p Saccharomyces cerevisiae S288C 35-39 2079689-5 1990 The major activation step is believed to be the oxygenation of the alpha-carbon catalysed by a Cytochrome P-450-dependent enzyme system commonly know as NDMA-demethylase. Carbon 73-79 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 95-111 2169024-1 1990 The Saccharomyces cerevisiae COX5b gene is regulated at the level of transcription by both the carbon source and oxygen. Carbon 95-101 cytochrome c oxidase subunit Vb Saccharomyces cerevisiae S288C 29-34 2246620-5 1990 In addition to the excellent enantiomer resolution, each enantiomer and the X-1,3-isomers were partially resolved into several peaks, which could be tentatively identified on the basis of equivalent carbon number. Carbon 199-205 Protein INVOLVED IN DE NOVO 2 Zea mays 76-79 1694407-1 1990 In canine airway epithelial cells, bradykinin increases intracellular concentrations of D-myo-inositol 1,4,5-trisphosphate [Ins(1,4,5)P3], cytosolic calcium concentration ([Ca2+]c), and adenosine 3",5"-cyclic monophosphate (cAMP). Carbon 3-4 kininogen 1 Canis lupus familiaris 35-45 9904219-0 1990 K-shell capture by He2+ and Li3+ on carbon and neon. Carbon 36-42 cytochrome P450 family 4 subfamily F member 22 Homo sapiens 28-31 2113050-4 1990 Reconstitution of the arachidonic acid oxygenase utilizing individual purified cytochrome P-450 enzymes demonstrates regioselectivity, controlled by the protein catalyst, for the hydroxylation of the sp3 carbon atoms adjacent to the methyl end of the fatty acid. Carbon 204-210 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 79-95 2113050-4 1990 Reconstitution of the arachidonic acid oxygenase utilizing individual purified cytochrome P-450 enzymes demonstrates regioselectivity, controlled by the protein catalyst, for the hydroxylation of the sp3 carbon atoms adjacent to the methyl end of the fatty acid. Carbon 204-210 Sp3 transcription factor Rattus norvegicus 200-203 2362271-6 1990 Upon the basis of this hypothesis indene 9 was prepared in which the "in plane" orientation of the carbonyl group is maintained by conjugation with the aromatic ring through the sp2 hybridized carbon. Carbon 99-105 Sp2 transcription factor Homo sapiens 178-181 2111350-4 1990 In addition, class I IFN is involved because IFN-alpha and IFN-beta act synergistically on TNF-alpha mediated lysis of 3LL-R cells within 18 h. Moreover, anticlass I IFN antibodies abolish the cytolytic capacity of Poly I:C-activated macrophages. Carbon 222-223 tumor necrosis factor Mus musculus 91-100 2372549-10 1990 Complete assignments are reported for the proton, carbon, and nitrogen backbone resonances of calmodulin, complexed with calcium. Carbon 50-56 calmodulin 1 Homo sapiens 94-104 2111350-3 1990 TNF-alpha participates in the cytolytic process of Poly I:C-activated macrophages as anti-TNF-alpha antibodies abolish the cytotoxic effect of these effector cells. Carbon 58-59 tumor necrosis factor Mus musculus 0-9 2111350-3 1990 TNF-alpha participates in the cytolytic process of Poly I:C-activated macrophages as anti-TNF-alpha antibodies abolish the cytotoxic effect of these effector cells. Carbon 58-59 tumor necrosis factor Mus musculus 90-99 2193978-1 1990 The Isoparaffins covered in this manuscript are branched aliphatic hydrocarbons with a carbon skeleton length ranging from approximately C10 to C15. Carbon 72-78 homeobox C10 Homo sapiens 137-140 2159183-4 1990 These effects increased according to the elongation of the carbon chain of 1-alkanols from ethanol (C2) to 1-decanol (C10), but suddenly almost disappeared at 1-tetradecanol (C14). Carbon 59-65 homeobox C10 Homo sapiens 118-121 2383621-0 1990 Influence of surface charge on adsorption of fibrinogen and/or albumin on a rotating disc electrode of platinum and carbon. Carbon 116-122 fibrinogen beta chain Homo sapiens 45-55 2324130-7 1990 The grafting of C2 and C18 alkyl groups onto 10 or 20% of the urethane linkages resulted in an increase in the percentage of aliphatic carbon species present on the surface. Carbon 135-141 Bardet-Biedl syndrome 9 Homo sapiens 23-26 2165822-3 1990 1.4-DHP was found to replace the fluorescent probe, diS-C3-(5), from the Ca2(+)-dependent calmodulin-dye complex (K0.5 = 4-60 microM) but at concentrations below 100 microM had no effect on the Ca2(+)-dependent troponin C-dye complex. Carbon 56-57 dihydropyrimidinase Homo sapiens 4-7 33813824-0 2021 Tetrahedrally Coordinated sp3-Hybridized Carbon in Sr2CO4 Orthocarbonate at Ambient Conditions. Carbon 41-47 Sp3 transcription factor Homo sapiens 26-29 24196256-4 1990 This relatively high methanogenic biomass implies that current microbial degradation of organic carbon in Ace Lake sediments may occur at extremely slow rates. Carbon 96-102 angiotensin I converting enzyme Homo sapiens 106-109 33973267-2 2021 Graphdiyne (GDY) is a new member of carbon-based 2D NMs possessing sp- and sp2 -hybridized carbon atoms. Carbon 36-42 Sp2 transcription factor Homo sapiens 75-78 33973267-2 2021 Graphdiyne (GDY) is a new member of carbon-based 2D NMs possessing sp- and sp2 -hybridized carbon atoms. Carbon 91-97 Sp2 transcription factor Homo sapiens 75-78 33766313-0 2021 Parts per trillion detection of heavy metals in as-is tap water using carbon nanotube microelectrodes. Carbon 70-76 SEC14 like lipid binding 2 Homo sapiens 54-57 2313290-1 1990 Rotating disk electrode voltammetry at glassy carbon electrodes and ultraviolet/visible spectroscopy were used to demonstrate that dopamine binds to neurotensin with a dissociation constant of 7.5 x 10(-8). Carbon 46-52 neurotensin Homo sapiens 149-160 2327077-1 1990 In this study it is demonstrated that complement-mediated antibody-dependent enhancement (C"-ADE) of HIV-1 infection in vitro is blocked by murine monoclonal antibodies to CD4 and complement receptor type 2 (CR2) while HIV-1 infection in the absence of C"-ADE is blocked by anti-CD4 but not anti-CR2 monoclonal antibodies. Carbon 90-93 CD4 molecule Homo sapiens 172-175 2327077-1 1990 In this study it is demonstrated that complement-mediated antibody-dependent enhancement (C"-ADE) of HIV-1 infection in vitro is blocked by murine monoclonal antibodies to CD4 and complement receptor type 2 (CR2) while HIV-1 infection in the absence of C"-ADE is blocked by anti-CD4 but not anti-CR2 monoclonal antibodies. Carbon 90-93 CD4 molecule Homo sapiens 279-282 2347029-3 1990 The most stable conformation was the one having C-19 and C-20 directed opposite to C-18, with respect to the average plane of the fourteen-membered ring. Carbon 48-49 Bardet-Biedl syndrome 9 Homo sapiens 83-87 2347029-3 1990 The most stable conformation was the one having C-19 and C-20 directed opposite to C-18, with respect to the average plane of the fourteen-membered ring. Carbon 57-58 Bardet-Biedl syndrome 9 Homo sapiens 83-87 33971443-8 2021 Therefore, the molecule DBP-1 with a carbon-carbon double bond as the pi bridge has the largest transition dipole moments, TPA cross-section, and second static hyperpolarizability. Carbon 37-43 DEAH-box helicase 15 Homo sapiens 24-29 33971443-8 2021 Therefore, the molecule DBP-1 with a carbon-carbon double bond as the pi bridge has the largest transition dipole moments, TPA cross-section, and second static hyperpolarizability. Carbon 44-50 DEAH-box helicase 15 Homo sapiens 24-29 33822444-2 2021 (1) The Ueno-Stork radical cyclization was applied to construct the adjacent quaternary centers at C-9 and C-22 positions; (2) a Co-catalyzed HAT radical reaction was successfully applied to construct the quaternary center at C-12 via Csp3-Csp2 bond formation; (3) a Mn-catalyzed HAT radical reaction was used to stereospecifically reduce the tetra-substituted olefin (C13=C18) and install the contiguous stereocenters in proximity to the quaternary center. Carbon 99-100 regulator of calcineurin 2 Homo sapiens 240-244 33944572-5 2021 The enantioconvergent reaction proceeds through a dynamic Walden cycle, involving an equilibrating mixture of enantiomers, initiated by a chiral aminocatalyst and terminated by a stereoselective SN2 reaction at a tertiary carbon to provide a quaternary carbon stereocenter. Carbon 222-228 solute carrier family 38 member 5 Homo sapiens 195-198 33944572-5 2021 The enantioconvergent reaction proceeds through a dynamic Walden cycle, involving an equilibrating mixture of enantiomers, initiated by a chiral aminocatalyst and terminated by a stereoselective SN2 reaction at a tertiary carbon to provide a quaternary carbon stereocenter. Carbon 253-259 solute carrier family 38 member 5 Homo sapiens 195-198 33971268-9 2021 Moreover, effects of intra-VTA infusion of lauric acid (a saturated fatty acid with 12 carbon) on food reward were abolished in mice lacking TLR4 in DA neurons. Carbon 87-93 toll-like receptor 4 Mus musculus 141-145 33773191-13 2021 Molecular docking simulation further evidenced that DS-1 interacts with MDM2 within the p53-binding domain by carbon-hydrogen bond interaction at Lys27, pi-alkyl interactions at Ile37 and Leu30, and van der Waals interactions at Ile75, Val51, Val69, Phe67, Met38, Tyr43, Gly34, and Phe31. Carbon 110-116 tumor protein p53 Homo sapiens 88-91 33813824-2 2021 We show by synchrotron powder X-ray diffraction, Raman spectroscopy, and density functional thoery calculations that this phase, and hence sp3-hybridized carbon in a CO44- group, can be recovered at ambient conditions. Carbon 154-160 Sp3 transcription factor Homo sapiens 139-142 33806023-5 2021 3-Methylpropyl(4-sulfamoylphenyl)carbamate (MBPC), reported and characterized here, is an MSPC analogous compound with two less aliphatic carbon atoms in its structure. Carbon 138-144 mannose binding lectin 2 Rattus norvegicus 44-48 33804795-6 2021 These superior adsorption effects can be attributed to the similar pore structures of CAP7-27 with those of alumina and the specific properties with those of carbon materials. Carbon 158-164 cathelicidin antimicrobial peptide Homo sapiens 86-93 33806971-5 2021 The C-O, C=O, P-O, and N-C bonds in the flame-retardant APP/EP composite were broken during the laser scribing, while the remaining carbon atoms recombined to generate the graphene layer. Carbon 132-138 amyloid beta precursor protein Homo sapiens 56-62 29136070-0 2017 Atomistic potential for graphene and other sp2 carbon systems. Carbon 47-53 Sp2 transcription factor Homo sapiens 43-46 33725138-1 2021 The transcription factors Cat8 and Sip4 were described in Saccharomyces cerevisiae and Kluyveromyces lactis to have very similar DNA binding domains and to be necessary for derepression of a variety of genes under non-fermentative growth conditions via binding to the carbon source responsive elements (CSREs). Carbon 268-274 Sip4p Saccharomyces cerevisiae S288C 35-39 33806675-0 2021 SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine-Glycine-One-Carbon Pathways in Cancer. Carbon 68-74 solute carrier family 38 member 5 Homo sapiens 12-19 33033627-2 2020 It is demonstrated that large negative and positive MOA and MPC effects can be tuned alternately in amorphous carbon ( a-C )/ZnO nanowires by controlling the sp2/sp3 ratio of a-C . Carbon 110-116 Sp2 transcription factor Homo sapiens 158-178 28395511-1 2017 The enormous versatility in the properties of carbon materials depends on the content of the sp2 and sp3 covalent bonds. Carbon 46-52 Sp2 transcription factor Homo sapiens 93-96 28395511-1 2017 The enormous versatility in the properties of carbon materials depends on the content of the sp2 and sp3 covalent bonds. Carbon 46-52 Sp3 transcription factor Homo sapiens 101-104 33800508-2 2021 The aim of this study is to characterize the changes in micro-structural properties of diamond layers with different grain sizes and different contents of sp2 carbon phase. Carbon 159-165 Sp2 transcription factor Homo sapiens 155-158 33588855-0 2021 Multi-carbon dots and aptamer based signal amplification ratiometric fluorescence probe for protein tyrosine kinase 7 detection. Carbon 6-12 protein tyrosine kinase 7 (inactive) Homo sapiens 92-117 33588855-8 2021 CONCLUSIONS: Summary, a multi-carbon dots and aptamer-based signal amplification ratiometric fluorescence probe was developed for the detection of protein tyrosine kinase 7. Carbon 30-36 protein tyrosine kinase 7 (inactive) Homo sapiens 147-172 33233383-0 2020 Functional Materials Based on Active Carbon and Titanium Dioxide in Fog Seal. Carbon 37-43 zinc finger protein, FOG family member 1 Homo sapiens 68-71 33233383-2 2020 To highlight the protection of road traffic environmental quality and mitigate automobile exhaust on human health, this study proposes combining titanium dioxide and active carbon into Sand-fog seal to form a pavement coating material with a photocatalytic function. Carbon 173-179 zinc finger protein, FOG family member 1 Homo sapiens 190-193 28804677-4 2017 Utilizing Ni/photoredox dual catalysis, Csp3 -Csp2 bonds can be forged selectively at the iodine-bearing carbon of bromo(iodo)arenes. Carbon 105-111 regulator of calcineurin 2 Homo sapiens 46-50 29136070-1 2017 We introduce a torsional force field for sp2 carbon to augment an in-plane atomistic potential of a previous work [G. Kalosakas et al., J. Appl. Carbon 45-51 Sp2 transcription factor Homo sapiens 41-44 29136070-4 2017 The aim is to create a force field that is as simple as possible so it can be efficient for large scale atomistic simulations of various sp2 carbon structures without significant loss of accuracy. Carbon 141-147 Sp2 transcription factor Homo sapiens 137-140 25756677-1 2015 Tryptophan-like fluorescence (TLF) is an indicator of human influence on water quality as TLF peaks are associated with the input of labile organic carbon (e.g. sewage or farm waste) and its microbial breakdown. Carbon 148-154 TATA-box binding protein like 1 Homo sapiens 30-33 25315061-4 2015 Excellent knockdown (~91%) expressions of Bmh1 in DeltaBmh2 and Bmh2 in DeltaBmh1 resulted in equally more severe multiphenotypic defects than the single deletions, including G2 /M transition, blastospore size, carbon/nitrogen utilization, conidiation, germination and conidial tolerances to high osmolarity, oxidation, cell wall stress, high temperature and UV-B irradiation. Carbon 211-217 14-3-3 family protein BMH1 Saccharomyces cerevisiae S288C 42-46 25756677-1 2015 Tryptophan-like fluorescence (TLF) is an indicator of human influence on water quality as TLF peaks are associated with the input of labile organic carbon (e.g. sewage or farm waste) and its microbial breakdown. Carbon 148-154 TATA-box binding protein like 1 Homo sapiens 90-93 34971965-3 2022 Herein, a type of biocompatible metal free carbon dots is prepared via a hydrothermal method which can exhibit peroxidase (POD)-like, catalase (CAT)-like and superoxide dismutase (SOD)-like activities. Carbon 43-49 catalase Mus musculus 144-147 12228600-8 1995 Under conditions in which respiratory carbon metabolism is restricted by the capacity of mitochondrial electron transport, feed-forward activation of AOX by mitochondrial reducing power and pyruvate may act to prevent redirection of carbon metabolism, such as to fermentative pathways. Carbon 38-44 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 150-153 12228600-8 1995 Under conditions in which respiratory carbon metabolism is restricted by the capacity of mitochondrial electron transport, feed-forward activation of AOX by mitochondrial reducing power and pyruvate may act to prevent redirection of carbon metabolism, such as to fermentative pathways. Carbon 233-239 ubiquinol oxidase 1, mitochondrial Nicotiana tabacum 150-153 34971965-3 2022 Herein, a type of biocompatible metal free carbon dots is prepared via a hydrothermal method which can exhibit peroxidase (POD)-like, catalase (CAT)-like and superoxide dismutase (SOD)-like activities. Carbon 43-49 catalase Mus musculus 134-142 34793843-2 2022 A tea-waste biosource carbon was explored by chemical vapor deposition (CVD) method at 700 C. The KOH-treated carbon (AC-KH) and H3PO4-treated carbon (AC-HP) were systematically studied for morphological characteristics and showed good morphological structures and a few transparent focused layered nanosheets. Carbon 144-150 limb development membrane protein 1 Homo sapiens 152-157 34743794-4 2022 The results showed that the NO3- denitrification removal increased with raised voltage and in proportion to the initial NO3- concentration within certain limits, wherein the removal rate reached a maximum of 53.3% in the single-solute solution of 200 mg L-1 NaNO3 at 1.8 V. Nevertheless, overhigh voltage or initial NO3- concentration would have a negative effect on nitrate removal, which was caused by multiple factors, including side reactions in the solution, fouling of activated carbon fiber and anion exchange membrane, and corrosion of copper electrode. Carbon 485-491 NBL1, DAN family BMP antagonist Homo sapiens 28-31 34743794-4 2022 The results showed that the NO3- denitrification removal increased with raised voltage and in proportion to the initial NO3- concentration within certain limits, wherein the removal rate reached a maximum of 53.3% in the single-solute solution of 200 mg L-1 NaNO3 at 1.8 V. Nevertheless, overhigh voltage or initial NO3- concentration would have a negative effect on nitrate removal, which was caused by multiple factors, including side reactions in the solution, fouling of activated carbon fiber and anion exchange membrane, and corrosion of copper electrode. Carbon 485-491 NBL1, DAN family BMP antagonist Homo sapiens 120-123 34743794-4 2022 The results showed that the NO3- denitrification removal increased with raised voltage and in proportion to the initial NO3- concentration within certain limits, wherein the removal rate reached a maximum of 53.3% in the single-solute solution of 200 mg L-1 NaNO3 at 1.8 V. Nevertheless, overhigh voltage or initial NO3- concentration would have a negative effect on nitrate removal, which was caused by multiple factors, including side reactions in the solution, fouling of activated carbon fiber and anion exchange membrane, and corrosion of copper electrode. Carbon 485-491 NBL1, DAN family BMP antagonist Homo sapiens 316-319 34923016-4 2022 The strong reduction in anthropogenic activities resulted in a marked decrease in dissolved organic carbon (DOC) concentration in the Arno River (-44%) and the coastal area affected by its input (-15%), compared to previous conditions. Carbon 100-106 cytohesin 2 Homo sapiens 134-138 34931704-3 2022 The mechanism includes two major steps: the formation of the carbon-carbon bond and the removal of SiH3 /BF2 by water. Carbon 61-67 forkhead box G1 Homo sapiens 105-108 34931704-3 2022 The mechanism includes two major steps: the formation of the carbon-carbon bond and the removal of SiH3 /BF2 by water. Carbon 68-74 forkhead box G1 Homo sapiens 105-108 34508772-3 2022 The physicochemical results showed that the NCD film had higher sp2 carbon content and greater doping level; this contributed to improvements in its surface roughness, as well as its specific capacitance and charge transfer, which consequently enhanced its electrocatalytic activity in comparison with the MCD. Carbon 68-74 Sp2 transcription factor Homo sapiens 64-67 34763890-2 2022 Herein, a Cu/C-700/Pd nanocomposite is obtained by loading trace Pd2+ onto carbon support derived from a novel mononuclear copper complex, {(Cu(POP)2(Phen)2)BF4}. Carbon 13-14 pyrin domain containing 2 Homo sapiens 144-149 34689109-3 2022 The redox reaction between the Sn2+ ions from the Zn-SnO-II sample and the surface oxygen-containing functional groups from functionalized carbon nanotube (F-CNT) and graphene oxide (GO) leads to the formation of the final Zn-SnO2/CNT@RGO composites. Carbon 139-145 solute carrier family 38 member 5 Homo sapiens 31-34 34763890-2 2022 Herein, a Cu/C-700/Pd nanocomposite is obtained by loading trace Pd2+ onto carbon support derived from a novel mononuclear copper complex, {(Cu(POP)2(Phen)2)BF4}. Carbon 75-81 pyrin domain containing 2 Homo sapiens 144-149 34728198-2 2022 Based on membrane biological activated carbon reactor (MBAR) technologies, the "Lunar Palace 365" experiment established various treatment processes for condensate wastewater, domestic wastewater, urine, and used nutrient solutions. Carbon 39-45 G protein-coupled bile acid receptor 1 Homo sapiens 55-59 34669188-5 2022 Such involvement has increased mitochondrial abundance/size and associated enzymatic capacity, and has altered mitochondrial location, ultrastructure and role in cellular carbon metabolism in the NAD-ME and PCK types. Carbon 171-177 malic enzyme 2 Homo sapiens 196-202 34865907-3 2022 Their uniqueness is that they can combine the advantages of quantum dots (rich functional groups at edge) and sp2 carbon materials (large specific surface area). Carbon 114-120 Sp2 transcription factor Homo sapiens 110-113 34794112-0 2022 A novel electrochemical insulin aptasensor: From glassy carbon electrodes to disposable, single-use laser-scribed graphene electrodes. Carbon 56-62 insulin Homo sapiens 24-31 34571226-5 2022 Mn doping enhances the signal for sp2-hybridised carbon-carbon double bond, forms more delocalised pi-bonds, and promotes the formation of free radicals centred on the carbon atoms. Carbon 49-55 Sp2 transcription factor Homo sapiens 34-37 34571226-5 2022 Mn doping enhances the signal for sp2-hybridised carbon-carbon double bond, forms more delocalised pi-bonds, and promotes the formation of free radicals centred on the carbon atoms. Carbon 56-62 Sp2 transcription factor Homo sapiens 34-37 34571226-5 2022 Mn doping enhances the signal for sp2-hybridised carbon-carbon double bond, forms more delocalised pi-bonds, and promotes the formation of free radicals centred on the carbon atoms. Carbon 168-174 Sp2 transcription factor Homo sapiens 34-37 34694734-12 2022 We then draw on these examples to demonstrate that the scope of the sigma-CAM mechanism has expanded to classes of reaction not envisaged in 2007 (additional s-bond ligands, agostic complexes, sp 2 -carbon, surfaces). Carbon 199-205 Sp2 transcription factor Homo sapiens 193-197 34736661-0 2022 Hierarchical nickel hydroxide nanosheets grown on hollow nitrogen doped carbon nanoboxes as a high-performance surface substrate for alpha-fetoprotein cancer biomarkers electrochemical aptasensing. Carbon 72-78 alpha fetoprotein Homo sapiens 133-150 34863066-6 2022 PPAR transactivation activity demonstrated that the seven-carbon side chain analogs (series 1) displayed selectivity for hPPARalpha, while the nine-carbon side chain analogs (polycerasoidol analogs, series 2) did so for hPPARgamma. Carbon 148-154 peroxisome proliferator activated receptor gamma Homo sapiens 220-230 34741650-3 2022 In our study, we developed an electrochemical biosensing platform based on gold clusters, mercaptoethanol, the spike protein of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antigen and bovine serum albumin-modified glassy carbon electrode able to detect the SARS-CoV-2 spike antibody. Carbon 238-244 albumin Homo sapiens 208-221 34764205-8 2022 Furthermore, MTHFD2, the key enzyme in one-carbon metabolism, was a target gene of beta-catenin and mediated the effects of NME7. Carbon 43-49 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase Mus musculus 13-19 34973938-3 2022 The magnetically responsive tumor cells were enriched and immobilized on a magnetic glassy carbon electrode (mGCE) surface, leading to increased electron-transfer resistance (Ret) utilized for determination of cells and preliminary evaluation of EGFR expression level. Carbon 91-97 epidermal growth factor receptor Homo sapiens 246-250 34619589-1 2022 Membrane photosynthetic microbial fuel cell (MPMFC) utilizes O2, NO3- and NO2- as cathodic electron acceptors, enabling simultaneous treatment of nitrogen, CO2 and organic carbon in the cathode compartment. Carbon 172-178 NBL1, DAN family BMP antagonist Homo sapiens 65-68 34954086-3 2022 Here, we show the first application of isotopically nonstationary 13C metabolic flux analysis to quantitatively measure carbon fluxes in both resting and thrombin activated platelets. Carbon 120-126 coagulation factor II, thrombin Homo sapiens 154-162 34794035-8 2021 Metabolic flux analysis around the mevalonate node, also revealed that significant amounts of acetoacetate are being produced from BCAA derived carbon, which could be at the source of lipid synthesis. Carbon 144-150 AT-rich interaction domain 4B Homo sapiens 131-135 34303053-0 2022 Efficient removal of a low concentration of Pb(II), Fe(III) and Cu(II) from simulated drinking water by co-immobilization between low-dosages of metal-resistant/adapted fungus Penicillium janthinillum and graphene oxide and activated carbon. Carbon 234-240 submaxillary gland androgen regulated protein 3B Homo sapiens 44-50 34951147-3 2022 Herein, we propose a versatile method to rapidly peel off ultrathin assembled LDM films, including three types of carbon nanotubes, vermiculite, Ag nanowires, and carbon nanotube@graphene, by dissolving the MXene interlayer from the layer-by-layer filtered MXene/LDM Janus films using diluted H2 O2 . Carbon 163-169 cytochrome P450 family 51 subfamily A member 1 Homo sapiens 78-81 34913689-3 2021 Here, CoSe2/nitrogen-doped carbon-skeleton hybrid microcubes with a TiO2 layer (denoted as TNC-CoSe2) are favorably prepared via a facile template-engaged strategy, in which a TiO2-coated Prussian blue analogue of Co3(Co(CN)6)2 is used as a new precursor accompanied with a selenization procedure. Carbon 27-33 tenascin C L homeolog Xenopus laevis 91-94 34957676-3 2022 The reaction also represents the enantioselective construction of carbon(sp 3 )-silicon bonds with nickel catalysis, which provides an atom- and step-economical synthesis route of high-value optically active alpha-difluoromethylsilanes. Carbon 66-72 Sp3 transcription factor Homo sapiens 73-77 34851111-6 2021 Analogues with IC50s below 5.0 muM against ACHN cells, when tested in the presence of TRAIL, showed a significantly increased ability to reduce cell number, and those analogues active against the M14 and SK-MEL-28 cell lines exhibited enhanced activity when combined with poly I:C. Carbon 279-280 TNF superfamily member 10 Homo sapiens 86-91 34969831-4 2022 To this end, a theophylline structure was connected to a pyrrolidine structure through a methylene chain of different lengths (3 to 7 carbon atoms) to give compounds 7-11 All caffeine derivatives inhibited the AChE, of which compound 11 showed the strongest effect. Carbon 134-140 acetylcholinesterase (Cartwright blood group) Homo sapiens 210-214 34963029-1 2022 We herein report a cyanide-free continuous-flow process for cyanation of sp 2 and sp carbons to synthesize aryl, vinyl and acetylenic nitriles from (5-methyl-2-phenyloxazol-4-yl) boronic acid (OxBA) reagent as a sole source of carbon-bound masked -CN source. Carbon 227-233 Sp2 transcription factor Homo sapiens 73-77 34992021-0 2022 Facile method to produce sub-1 nm pore-rich carbon from biomass wastes for high performance supercapacitors. Carbon 44-50 SUB1 regulator of transcription Homo sapiens 25-30 34992021-2 2022 Here we successfully prepared a sub-1 nm pore-rich carbon from biomass wastes using a facile method by pre-treating walnut shell powder at 380 C in air for different times to delicately tailor carbon defects, followed by KOH activation at 700 C. The as-prepared optimal material delivers the highest sub-1 nm pore content (Vsub-1 nm = 0.57 cm3 g-1, Vsub-1 nm/Vt = 58.4 %) among all reported porous carbons. Carbon 51-57 SUB1 regulator of transcription Homo sapiens 32-37 34992021-2 2022 Here we successfully prepared a sub-1 nm pore-rich carbon from biomass wastes using a facile method by pre-treating walnut shell powder at 380 C in air for different times to delicately tailor carbon defects, followed by KOH activation at 700 C. The as-prepared optimal material delivers the highest sub-1 nm pore content (Vsub-1 nm = 0.57 cm3 g-1, Vsub-1 nm/Vt = 58.4 %) among all reported porous carbons. Carbon 51-57 SUB1 regulator of transcription Homo sapiens 300-305 34992021-2 2022 Here we successfully prepared a sub-1 nm pore-rich carbon from biomass wastes using a facile method by pre-treating walnut shell powder at 380 C in air for different times to delicately tailor carbon defects, followed by KOH activation at 700 C. The as-prepared optimal material delivers the highest sub-1 nm pore content (Vsub-1 nm = 0.57 cm3 g-1, Vsub-1 nm/Vt = 58.4 %) among all reported porous carbons. Carbon 193-199 SUB1 regulator of transcription Homo sapiens 32-37 34992021-5 2022 More importantly, it drives a light-emitting-diode (LED) to operate for as long as 20 min, vividly demonstrating the great potential of sub-1 nm pore-rich carbon-based high performance supercapacitors in practical applications. Carbon 155-161 SUB1 regulator of transcription Homo sapiens 136-141 34951147-3 2022 Herein, we propose a versatile method to rapidly peel off ultrathin assembled LDM films, including three types of carbon nanotubes, vermiculite, Ag nanowires, and carbon nanotube@graphene, by dissolving the MXene interlayer from the layer-by-layer filtered MXene/LDM Janus films using diluted H2 O2 . Carbon 163-169 cytochrome P450 family 51 subfamily A member 1 Homo sapiens 263-266 34878792-5 2021 (Bmim)(FAP) on amorphous carbon shows a fairly smooth film for the thinner nanofilms, which can be attributed to the pi-pi+ parallel stacking between the cation imidazolium ring and the randomly distributed sp2 carbon on the amorphous carbon surface. Carbon 25-31 Sp2 transcription factor Homo sapiens 207-210 34931425-5 2022 The new sp 2 carbon frameworks are highly emissive and enable up-conversion luminescence, offer low bandgap semiconductors with tunable band structures, and achieve ultrahigh charge mobilities close to theoretically predicted maxima. Carbon 14-20 Sp2 transcription factor Homo sapiens 8-12 34669980-0 2021 The Formal Cross-Coupling of Amines and Carboxylic Acids to Form sp3-sp3 Carbon-Carbon Bonds. Carbon 73-79 Sp3 transcription factor Homo sapiens 65-68 34902253-0 2021 Photochemical Deracemization at sp3-Hybridized Carbon Centers via a Reversible Hydrogen Atom Transfer. Carbon 47-53 Sp3 transcription factor Homo sapiens 32-35 34878792-5 2021 (Bmim)(FAP) on amorphous carbon shows a fairly smooth film for the thinner nanofilms, which can be attributed to the pi-pi+ parallel stacking between the cation imidazolium ring and the randomly distributed sp2 carbon on the amorphous carbon surface. Carbon 211-217 Sp2 transcription factor Homo sapiens 207-210 34878792-5 2021 (Bmim)(FAP) on amorphous carbon shows a fairly smooth film for the thinner nanofilms, which can be attributed to the pi-pi+ parallel stacking between the cation imidazolium ring and the randomly distributed sp2 carbon on the amorphous carbon surface. Carbon 235-241 Sp2 transcription factor Homo sapiens 207-210 34875834-1 2021 Graphdiyne (GD), a new type of carbon allotrope formed by sp and sp2 hybrid carbon atoms, has attracted wide attention due to its high pi-conjugation degree, special band structure, and uniformly distributed pores. Carbon 31-37 Sp2 transcription factor Homo sapiens 65-68 34669980-0 2021 The Formal Cross-Coupling of Amines and Carboxylic Acids to Form sp3-sp3 Carbon-Carbon Bonds. Carbon 73-79 Sp3 transcription factor Homo sapiens 69-72 34669980-0 2021 The Formal Cross-Coupling of Amines and Carboxylic Acids to Form sp3-sp3 Carbon-Carbon Bonds. Carbon 80-86 Sp3 transcription factor Homo sapiens 65-68 34669980-0 2021 The Formal Cross-Coupling of Amines and Carboxylic Acids to Form sp3-sp3 Carbon-Carbon Bonds. Carbon 80-86 Sp3 transcription factor Homo sapiens 69-72 34669980-1 2021 We have developed a deaminative-decarboxylative protocol to form sp3-sp3 carbon-carbon bonds from activated amines and carboxylic acids. Carbon 73-79 Sp3 transcription factor Homo sapiens 65-68 34669980-1 2021 We have developed a deaminative-decarboxylative protocol to form sp3-sp3 carbon-carbon bonds from activated amines and carboxylic acids. Carbon 73-79 Sp3 transcription factor Homo sapiens 69-72 34669980-1 2021 We have developed a deaminative-decarboxylative protocol to form sp3-sp3 carbon-carbon bonds from activated amines and carboxylic acids. Carbon 80-86 Sp3 transcription factor Homo sapiens 65-68 34669980-1 2021 We have developed a deaminative-decarboxylative protocol to form sp3-sp3 carbon-carbon bonds from activated amines and carboxylic acids. Carbon 80-86 Sp3 transcription factor Homo sapiens 69-72 34875834-1 2021 Graphdiyne (GD), a new type of carbon allotrope formed by sp and sp2 hybrid carbon atoms, has attracted wide attention due to its high pi-conjugation degree, special band structure, and uniformly distributed pores. Carbon 76-82 Sp2 transcription factor Homo sapiens 65-68 34854690-3 2021 Further C-C bond scission is promoted by the intramolecular SN2 reaction. Carbon 8-9 solute carrier family 38 member 5 Homo sapiens 60-63 34927368-1 2022 Activating inert sp 3 -sp 3 carbon-carbon (C-C) bonds remains a major bottleneck in the chemical upcycling of recalcitrant polyolefin waste. Carbon 45-46 Sp3 transcription factor Homo sapiens 23-27 34927368-1 2022 Activating inert sp 3 -sp 3 carbon-carbon (C-C) bonds remains a major bottleneck in the chemical upcycling of recalcitrant polyolefin waste. Carbon 28-34 Sp3 transcription factor Homo sapiens 17-21 34927368-1 2022 Activating inert sp 3 -sp 3 carbon-carbon (C-C) bonds remains a major bottleneck in the chemical upcycling of recalcitrant polyolefin waste. Carbon 28-34 Sp3 transcription factor Homo sapiens 23-27 34927368-1 2022 Activating inert sp 3 -sp 3 carbon-carbon (C-C) bonds remains a major bottleneck in the chemical upcycling of recalcitrant polyolefin waste. Carbon 35-41 Sp3 transcription factor Homo sapiens 17-21 34927368-1 2022 Activating inert sp 3 -sp 3 carbon-carbon (C-C) bonds remains a major bottleneck in the chemical upcycling of recalcitrant polyolefin waste. Carbon 35-41 Sp3 transcription factor Homo sapiens 23-27 34927368-1 2022 Activating inert sp 3 -sp 3 carbon-carbon (C-C) bonds remains a major bottleneck in the chemical upcycling of recalcitrant polyolefin waste. Carbon 43-44 Sp3 transcription factor Homo sapiens 17-21 34927368-1 2022 Activating inert sp 3 -sp 3 carbon-carbon (C-C) bonds remains a major bottleneck in the chemical upcycling of recalcitrant polyolefin waste. Carbon 43-44 Sp3 transcription factor Homo sapiens 23-27 34927368-1 2022 Activating inert sp 3 -sp 3 carbon-carbon (C-C) bonds remains a major bottleneck in the chemical upcycling of recalcitrant polyolefin waste. Carbon 45-46 Sp3 transcription factor Homo sapiens 17-21 34854690-3 2021 Further C-C bond scission is promoted by the intramolecular SN2 reaction. Carbon 10-11 solute carrier family 38 member 5 Homo sapiens 60-63 34543954-3 2021 All the AR E. coli (~8 log) was inactivated and 8.17 log blaTEM-1 was degraded by the carbon nanotubes/agarose/titanium (CNTs/AG/Ti) electrode within 30 min. Carbon 86-92 beta-lactamase Escherichia coli 57-65 34794569-4 2021 While introducing numerous amino groups, the melamine functionalized hollow mesoporous carbon spheres (NH2-HMCS) retained the edge-plane-like defective sites for the adhesion and electrocatalytic reduction of H2O2. Carbon 87-93 MKKS centrosomal shuttling protein Homo sapiens 107-111 34794579-0 2021 Sensitive ratiometric fluorescence probe based on chitosan carbon dots and calcein for Alkaline phosphatase detection and bioimaging in cancer cells. Carbon 59-65 alkaline phosphatase, placental Homo sapiens 87-107 34947764-0 2021 Single-Walled Carbon Nanotubes Inhibit TRPC4-Mediated Muscarinic Cation Current in Mouse Ileal Myocytes. Carbon 14-20 transient receptor potential cation channel, subfamily C, member 4 Mus musculus 39-44 34293531-4 2021 EXPERIMENTS: We presented a phase-transition lysozyme coating approach to fabricate porous carbon nanotube microspheres with tailorable surface wettability areas for versatile oil adsorption. Carbon 91-97 lysozyme Homo sapiens 45-53 34898425-6 2022 From heading to 14days post-anthesis, wheat pericarps exhibited a strong, positive correlation between biological capacity for carbon assimilation and expression of key genes related to sucrose metabolism (SPS1, SUS1 and SPP1). Carbon 127-133 probable sucrose-phosphate synthase 5 Triticum aestivum 206-210 34846871-7 2021 The calculated mechanism indicates that the spin crossover is sped up by many orders of magnitude due to multidimensional quantum tunneling of the carbon atom even at room temperature. Carbon 147-153 spinster Drosophila melanogaster 44-48 34802226-1 2021 In this work, a novel electrochemical immunosensor based on nitrogen doped graphene quantum dot (N-GQD) and single-walled carbon nanohorns (SWCNHs) was developed for the detection of alpha-fetoprotein (AFP), a cancer biomarker. Carbon 122-128 alpha fetoprotein Homo sapiens 183-200 34802226-1 2021 In this work, a novel electrochemical immunosensor based on nitrogen doped graphene quantum dot (N-GQD) and single-walled carbon nanohorns (SWCNHs) was developed for the detection of alpha-fetoprotein (AFP), a cancer biomarker. Carbon 122-128 alpha fetoprotein Homo sapiens 202-205 34775756-5 2021 These results indicate that the ET process is involved in the rate-limiting step and coupled with the following O-C bond formation process: ET coupled bond formation mechanism. Carbon 114-115 major facilitator superfamily domain containing 11 Homo sapiens 32-34 34944777-7 2021 These data suggest that the cellular activity of Nrf2-driven antioxidant systems is a possible determinant of carbon ion RBE predictable by 64Cu-ATSM uptake. Carbon 110-116 NFE2 like bZIP transcription factor 2 Homo sapiens 49-53 34591076-8 2021 Thus, GFP-Gpc4-labeled protrusions that emanated from endodermal cells transported Wnt5b and Wnt11f2 to other germ layers, rescuing the C&E defects caused by a gpc4 deficiency. Carbon 136-137 wingless-type MMTV integration site family, member 5b Danio rerio 83-88 34984262-3 2021 Experiments for the production of a carbon material were conducted using three kinds of heavy petroleum residues of the oil refinery plant Ltd Kinef: the vacuum residue from crude atmospheric and vacuum distillation units (VR1), the vacuum residue from the vacuum distillation hydrocracking unit (VR2), and the visbreaker residue from the visbreaking unit (VR3). Carbon 36-42 vault RNA 1-3 Homo sapiens 357-360 34950134-9 2021 Furthermore, imiquimod increased IFN-beta expression, an effect potentiated in presence of poly(I:C) or SP1. Carbon 98-100 IFN1@ Homo sapiens 33-41 34775756-5 2021 These results indicate that the ET process is involved in the rate-limiting step and coupled with the following O-C bond formation process: ET coupled bond formation mechanism. Carbon 114-115 major facilitator superfamily domain containing 11 Homo sapiens 140-142 34775756-9 2021 The shift of one electron from the HOMO of the alkene by the ET simultaneously results in the O-C half bond formation between the oxo ligand and the alkene. Carbon 96-97 major facilitator superfamily domain containing 11 Homo sapiens 61-63 34739983-4 2021 Herein, we report the interaction between zero-to three-dimensional carbon nanostructures and the amyloid-beta protein, which can either activate or interrupt neuronal functions, depending on the dimension of the carbon nanostructures. Carbon 68-74 amyloid beta precursor protein Homo sapiens 98-110 34893855-10 2022 Prenatal Poly I:C exposure decreased expression of GABAA receptor subunits Gabrb3 in the PFC, and Gabrb1 and dopamine D2 (Drd2) in the hippocampus, but increased NMDA receptor subunit Grin2a in the PFC, 5-HT2A in the hippocampus, and Gabrb3 and Drd2 in the NAc. Carbon 16-17 glutamate ionotropic receptor NMDA type subunit 2A Rattus norvegicus 184-190 34893855-10 2022 Prenatal Poly I:C exposure decreased expression of GABAA receptor subunits Gabrb3 in the PFC, and Gabrb1 and dopamine D2 (Drd2) in the hippocampus, but increased NMDA receptor subunit Grin2a in the PFC, 5-HT2A in the hippocampus, and Gabrb3 and Drd2 in the NAc. Carbon 16-17 gamma-aminobutyric acid type A receptor subunit beta 3 Rattus norvegicus 234-240 34797680-0 2021 High-Throughput Screening of Two-Dimensional Planar sp2 Carbon Space Associated with a Labeled Quotient Graph. Carbon 56-62 Sp2 transcription factor Homo sapiens 52-55 34797680-1 2021 The configurational space of two-dimensional planar sp2 carbon has been systematically scanned by a random strategy combined with group and graph theory, and 1114 new carbon allotropes have been identified. Carbon 56-62 Sp2 transcription factor Homo sapiens 52-55 34797680-1 2021 The configurational space of two-dimensional planar sp2 carbon has been systematically scanned by a random strategy combined with group and graph theory, and 1114 new carbon allotropes have been identified. Carbon 167-173 Sp2 transcription factor Homo sapiens 52-55 34797680-6 2021 In particular, one nodal-line semimetal has been discovered among these thousands of allotropes, which is the first nodal-line semimetal in sp2 carbon systems. Carbon 144-150 Sp2 transcription factor Homo sapiens 140-143 34893855-9 2022 Prenatal Poly I:C exposure caused brain region-specific elevation of the P2X7 receptor- and NF-kappaB-NLRP3-IL-1beta inflammatory signalling in female juvenile rats. Carbon 16-17 NLR family, pyrin domain containing 3 Rattus norvegicus 102-107 34893855-9 2022 Prenatal Poly I:C exposure caused brain region-specific elevation of the P2X7 receptor- and NF-kappaB-NLRP3-IL-1beta inflammatory signalling in female juvenile rats. Carbon 16-17 interleukin 1 alpha Rattus norvegicus 108-116 34893855-10 2022 Prenatal Poly I:C exposure decreased expression of GABAA receptor subunits Gabrb3 in the PFC, and Gabrb1 and dopamine D2 (Drd2) in the hippocampus, but increased NMDA receptor subunit Grin2a in the PFC, 5-HT2A in the hippocampus, and Gabrb3 and Drd2 in the NAc. Carbon 16-17 gamma-aminobutyric acid type A receptor subunit beta 3 Rattus norvegicus 75-81 34899874-2 2021 How ecosystem carbon exchange in global drylands (CED) occurs and how climate change affects CED are critical to the global carbon cycle. Carbon 14-20 intraflagellar transport 122 Homo sapiens 50-53 34899874-2 2021 How ecosystem carbon exchange in global drylands (CED) occurs and how climate change affects CED are critical to the global carbon cycle. Carbon 124-130 intraflagellar transport 122 Homo sapiens 50-53 34899874-2 2021 How ecosystem carbon exchange in global drylands (CED) occurs and how climate change affects CED are critical to the global carbon cycle. Carbon 124-130 intraflagellar transport 122 Homo sapiens 93-96 34899874-8 2021 Keywords were classified into five clusters, indicating the five main research focuses on CED studies: hydrological cycle, effects of climate change, carbon and water balance, productivity, and carbon-nitrogen-phosphorous coupling cycles. Carbon 150-156 intraflagellar transport 122 Homo sapiens 90-93 34899874-8 2021 Keywords were classified into five clusters, indicating the five main research focuses on CED studies: hydrological cycle, effects of climate change, carbon and water balance, productivity, and carbon-nitrogen-phosphorous coupling cycles. Carbon 194-200 intraflagellar transport 122 Homo sapiens 90-93 34739983-4 2021 Herein, we report the interaction between zero-to three-dimensional carbon nanostructures and the amyloid-beta protein, which can either activate or interrupt neuronal functions, depending on the dimension of the carbon nanostructures. Carbon 213-219 amyloid beta precursor protein Homo sapiens 98-110 34739983-7 2021 The inclusion of amyloid-beta proteins ameliorated the cytotoxic effects of carbon nanomaterials in higher-dimensional carbon nanomaterials by regulating 333 genes. Carbon 76-82 amyloid beta precursor protein Homo sapiens 17-29 34739983-7 2021 The inclusion of amyloid-beta proteins ameliorated the cytotoxic effects of carbon nanomaterials in higher-dimensional carbon nanomaterials by regulating 333 genes. Carbon 119-125 amyloid beta precursor protein Homo sapiens 17-29 34229816-7 2021 Whereas, only sp3 C-O (ether/hydroxy) components were observed after shorter exposure times. Carbon 18-19 Sp3 transcription factor Homo sapiens 14-17 34481349-3 2021 The Fe2O3-BCN nanosheets were used to modified on the surface of the glassy carbon electrode to fabricate an electrochemical sensor for lead ions (Pb(II)) via differential pulse anodic stripping voltammetry (DPASV). Carbon 76-82 submaxillary gland androgen regulated protein 3B Homo sapiens 147-153 34275083-4 2021 Also, TR, GPC, and EPI decrease carbon emissions both in the long and short term . Carbon 32-38 coagulation factor II thrombin receptor Homo sapiens 6-8 34192988-4 2021 Incorporation of glucose-derived carbons entering the TCA cycle via pyruvate carboxylase was enhanced by NCT-503 treatment. Carbon 33-40 pyruvate carboxylase Homo sapiens 68-88 34762090-1 2021 Graphdiyne (GDY), which possess sp- and sp2-hybridized carbon and Dirac cones, offers unique physical and chemical properties, including an adjustable intrinsic bandgap, excellent charge carrier transfer efficiency, and superior conductivity compared to other carbon allotropes. Carbon 55-61 Sp2 transcription factor Homo sapiens 40-43 34784468-1 2021 Hindered rotation about an sp2 C-N bond is known to occur in arginine (Arg), asparagine (Asn), and glutamine (Gln) side chains of proteins. Carbon 31-32 Sp2 transcription factor Homo sapiens 27-30 34517598-5 2021 The concentration of cofactors (NADH, NAD+) and substrates (fructose, sorbitol) for SDH determination at a strip was optimized via internally-calibrated amperometric assays at a chitosan/nitrogen-doped carbon nanotube electrode. Carbon 202-208 sorbitol dehydrogenase Homo sapiens 84-87 34928839-6 2021 The results of interaction energies between the model molecule and Pb(II) cation show that Pb(II) cation and -C-O-C are most easily combined, followed by -COOH, and -C = O is the weakest. Carbon 110-111 submaxillary gland androgen regulated protein 3B Homo sapiens 67-73 34928839-6 2021 The results of interaction energies between the model molecule and Pb(II) cation show that Pb(II) cation and -C-O-C are most easily combined, followed by -COOH, and -C = O is the weakest. Carbon 114-115 submaxillary gland androgen regulated protein 3B Homo sapiens 67-73 34856260-5 2022 The net ecosystem carbon budget of the biochar scenario exhibits an unprecedentedly positive value of 17.8 t CO2-eq ha-1, which can finely contribute to a positive carbon budget during remediation. Carbon 18-24 Rho GTPase activating protein 45 Homo sapiens 116-120 34856260-5 2022 The net ecosystem carbon budget of the biochar scenario exhibits an unprecedentedly positive value of 17.8 t CO2-eq ha-1, which can finely contribute to a positive carbon budget during remediation. Carbon 164-170 Rho GTPase activating protein 45 Homo sapiens 116-120 34608685-3 2021 The reaction of 1 with one equiv of PhCOMe, Ar 1 CHO (Ar 1 = 2,6-Me 2 C 6 H 3 ), W(CO) 6 , and PhCH=NPh provided oxalutetacyclopentenes, metallacyclic lutetoxycarbene, and azalutetacyclopentene via 1,2-insertion of C=O, C O, or C=N bonds into Lu-C sp2 bond, respectively. Carbon 215-216 regulator of calcineurin 2 Homo sapiens 246-251 34850465-5 2022 The synergetic "order in disorder" structure ensures high concentration of reversible carbon-vacancies and fast charge transfer kinetics simultaneously, leading to high reversible capacity (425 mAh g-1 at 0.05 A g-1 ), high-rate (237.4 mAh g-1 at 1 A g-1 ) and superior cyclic stability (90.4% capacity retention from cycle 10 to 400 at 0.1 A g-1 ). Carbon 86-92 NBPF member 10 Homo sapiens 210-215 34850465-5 2022 The synergetic "order in disorder" structure ensures high concentration of reversible carbon-vacancies and fast charge transfer kinetics simultaneously, leading to high reversible capacity (425 mAh g-1 at 0.05 A g-1 ), high-rate (237.4 mAh g-1 at 1 A g-1 ) and superior cyclic stability (90.4% capacity retention from cycle 10 to 400 at 0.1 A g-1 ). Carbon 86-92 NBPF member 10 Homo sapiens 341-346 34888245-0 2021 High-LET Carbon and Iron Ions Elicit a Prolonged and Amplified p53 Signaling and Inflammatory Response Compared to low-LET X-Rays in Human Peripheral Blood Mononuclear Cells. Carbon 9-15 tumor protein p53 Homo sapiens 63-66 34849401-5 2021 This involved the reaction of 6 equiv of TosMIC in a "multistep, single-substrate" cascade reaction yielding a trimeric product in high yield (47% unoptimized) with the formation of five new C-C bonds involving sp-sp2 and sp-sp3 carbon centers. Carbon 191-192 Sp2 transcription factor Homo sapiens 214-217 34849401-5 2021 This involved the reaction of 6 equiv of TosMIC in a "multistep, single-substrate" cascade reaction yielding a trimeric product in high yield (47% unoptimized) with the formation of five new C-C bonds involving sp-sp2 and sp-sp3 carbon centers. Carbon 193-194 Sp2 transcription factor Homo sapiens 214-217 34779209-7 2021 By synchronous fluorescence and circular dichroism spectroscopic studies, it was deduced that both AuNCs would interact with Lys by electrostatic attractions due to the distinct surface charges, and then DHLA-AuNCs would further interact with Lys by hydrophobic interactions, probably due to the hydrophobic carbon chain of DHLA and the hydrophobic side chains of amino acid residues in Lys, which was proved by the significant secondary structure changes caused by DHLA-AuNCs. Carbon 308-314 lysozyme Homo sapiens 243-246 34147753-0 2021 Carbon nanotubes interpenetrating MOFs-derived Co-Ni-S composite spheres with interconnected architecture for high performance hybrid supercapacitor. Carbon 0-6 solute carrier family 5 member 5 Homo sapiens 50-54 34510789-4 2021 Herein, we report an efficient method for selective degradation of styrene-related plastics under gentle conditions through multiple oxidation of sp 3 C-H bonds and sp 3 C-C bonds. Carbon 170-171 Sp3 transcription factor Homo sapiens 165-169 34510789-4 2021 Herein, we report an efficient method for selective degradation of styrene-related plastics under gentle conditions through multiple oxidation of sp 3 C-H bonds and sp 3 C-C bonds. Carbon 172-173 Sp3 transcription factor Homo sapiens 165-169 34738807-0 2021 A Covalent Heterostructure of Metal Phosphide Quantum Dots Anchored in N, P Co-doped Carbon Nanocapsules for Fast and Durable Lithium Storage. Carbon 85-91 Fas activated serine/threonine kinase Homo sapiens 109-113 34543526-2 2021 The four 4-hexylphenyl groups at the sp3-carbon bridges of DHDNP were acquainted with control morphology and improving solubility. Carbon 41-47 Sp3 transcription factor Homo sapiens 37-40 34901602-0 2021 Fabrication of GQD-Electrodeposited Screen-Printed Carbon Electrodes for the Detection of the CRP Biomarker. Carbon 51-57 C-reactive protein Homo sapiens 94-97 34831878-2 2021 We examined the cumulative short-term effect of black carbon (BC) exposure on systolic (SBP) and diastolic (DBP) BP and assessed effect modification by participant characteristics. Carbon 54-60 D-box binding PAR bZIP transcription factor Homo sapiens 108-111 34147753-2 2021 Herein, a three-dimensional (3D) interconnected network structure combined with conductive carbon nanotubes interpenetrating MOFs-derived Co-Ni-S composite spheres (Co-Ni-S/CNTs) was synthesized. Carbon 91-97 solute carrier family 5 member 5 Homo sapiens 141-145 34147753-2 2021 Herein, a three-dimensional (3D) interconnected network structure combined with conductive carbon nanotubes interpenetrating MOFs-derived Co-Ni-S composite spheres (Co-Ni-S/CNTs) was synthesized. Carbon 91-97 solute carrier family 5 member 5 Homo sapiens 168-172 34633825-0 2021 Enantioselective Cross-Coupling of Electron-Deficient Alkenes via Ir-Catalyzed Vinylic sp2 C-H Alkylation. Carbon 91-92 Sp2 transcription factor Homo sapiens 87-90 34699721-5 2021 DFT calculations for model oligomers suggest a Mg-templated SRN1-type coupling, in which Grignard monomer coordination to the radical anion chain avoids the formation of free sp2 radicals and allows C-C bond formation with very low barriers. Carbon 199-200 NPHS2 stomatin family member, podocin Homo sapiens 60-64 34699721-5 2021 DFT calculations for model oligomers suggest a Mg-templated SRN1-type coupling, in which Grignard monomer coordination to the radical anion chain avoids the formation of free sp2 radicals and allows C-C bond formation with very low barriers. Carbon 201-202 NPHS2 stomatin family member, podocin Homo sapiens 60-64 34764285-6 2021 Experimental characterizations and density functional theory calculations reveal that the fluorine functionalization not only promotes the conversion of sp3 to sp2 carbon to generate graphitic layers but also stimulates and increases the active sites (ketonic C=O). Carbon 164-170 Sp3 transcription factor Homo sapiens 153-156 34764285-6 2021 Experimental characterizations and density functional theory calculations reveal that the fluorine functionalization not only promotes the conversion of sp3 to sp2 carbon to generate graphitic layers but also stimulates and increases the active sites (ketonic C=O). Carbon 164-170 Sp2 transcription factor Homo sapiens 160-163 34617947-0 2021 Carbon dots up-regulate heme oxygenase-1 expression towards acute lung injury therapy. Carbon 0-6 heme oxygenase 1 Mus musculus 24-40 34617947-3 2021 Here, we demonstrate that degradable carbon dots (from L-ascorbic acid, CDs-1) can up-regulate the expression of HMOX1 in animal cells and tissues, which has a therapeutic effect on LPS-induced acute lung injury in mice. Carbon 37-43 CDP-diacylglycerol synthase 1 Mus musculus 72-77 34617947-3 2021 Here, we demonstrate that degradable carbon dots (from L-ascorbic acid, CDs-1) can up-regulate the expression of HMOX1 in animal cells and tissues, which has a therapeutic effect on LPS-induced acute lung injury in mice. Carbon 37-43 heme oxygenase 1 Mus musculus 113-118 34672313-4 2021 Kinetic isotope experiments and DFT calculations support a catalytic pathway involving the ligand-assisted oxidative addition of the sp2 C-O bond to a Pd-Al intermetallic complex. Carbon 137-138 Sp2 transcription factor Homo sapiens 133-136 34732697-10 2021 Here, the use of carbon ion beams (5 GyE) for melanoma-bearing mice was found to reduce the population of MDSC in the bone marrow, peripheral blood, and spleen of the animals via a JAK2/STAT3-dependent mechanism. Carbon 17-23 signal transducer and activator of transcription 3 Mus musculus 186-191 34805660-1 2021 An intrinsic ion sensitivity exceeding the Nernst-Boltzmann limit and an sp 2 -hybridized carbon structure make graphene a promising channel material for realizing ion-sensitive field-effect transistors with a stable solid-liquid interface under biased conditions in buffered salt solutions. Carbon 90-96 Sp2 transcription factor Homo sapiens 73-77 34622268-3 2021 What"s more challenging for synthetic chemists are the consecutive sp2-hybridized carbon centers, which exacerbates the strain/rigidity of the whole molecule. Carbon 82-88 Sp2 transcription factor Homo sapiens 67-70 34772142-3 2021 The obtained PDFs were characterized by scanning electron microscopy (SEM) and Raman spectroscopy which, in addition to the diamond phase, also confirms the presence of sp2 hybridized carbon bonds. Carbon 184-190 Sp2 transcription factor Homo sapiens 169-172 34909151-0 2021 Carbon-carbon bond activation by B(OMe)3/B2pin2-mediated fragmentation borylation. Carbon 0-6 telomeric repeat binding factor 1 Homo sapiens 43-47 34467664-1 2021 2D Graphdiyne (GDY), a rapidly rising star on the horizon of carbon materials, is a new carbon allotrope featuring sp- and sp2-cohybridized carbon atoms and two-dimensional one-atom-thick network. Carbon 61-67 Sp2 transcription factor Homo sapiens 123-126 34467664-1 2021 2D Graphdiyne (GDY), a rapidly rising star on the horizon of carbon materials, is a new carbon allotrope featuring sp- and sp2-cohybridized carbon atoms and two-dimensional one-atom-thick network. Carbon 88-94 Sp2 transcription factor Homo sapiens 123-126 34467664-1 2021 2D Graphdiyne (GDY), a rapidly rising star on the horizon of carbon materials, is a new carbon allotrope featuring sp- and sp2-cohybridized carbon atoms and two-dimensional one-atom-thick network. Carbon 140-146 Sp2 transcription factor Homo sapiens 123-126 34909151-0 2021 Carbon-carbon bond activation by B(OMe)3/B2pin2-mediated fragmentation borylation. Carbon 7-13 telomeric repeat binding factor 1 Homo sapiens 43-47 34672557-0 2021 A Shift from Snow to Rain in Midlatitude Japan Increases Fresh Submarine Groundwater Discharge and Doubled Inorganic Carbon Flux over 20 Years. Carbon 117-123 Ras interacting protein 1 Homo sapiens 21-25 34672608-3 2021 In the neutral solution, the electrocatalytic performance of the CNP@PNS-4 catalyst exhibits an onset potential of 0.98 V (vs reversible hydrogen electrode) and a half-wave potential of 0.91 V for ORR, which greatly surpasses commercial Pt/C (40%). Carbon 240-241 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 65-68 34728685-3 2021 In this work, the immobilization of ASNase by adsorption over pristine and modified multi-walled carbon nanotubes (MWCNTs) was investigated, the latter corresponding to functionalized MWCNTs through a hydrothermal oxidation treatment. Carbon 97-103 asparaginase and isoaspartyl peptidase 1 Homo sapiens 36-42 34661594-4 2021 In addition to the traditional advantages of fast electron transport and polysulfide-interception ability of the carbon coating layer, the grafted organo-polysulfide chain endows the ABPS coating layer with permselectivity for lithium ion against polysulfides, electrocatalytic ability for the sluggish redox kinetics and self-repairing ability for the broken electrode. Carbon 113-119 Fas activated serine/threonine kinase Homo sapiens 45-49 34761234-2 2021 However, the innate capacity of autotrophic plants to produce carbon-related nutrients and nitrogen-related nutrients makes studying the TOR pathway difficult. Carbon 62-68 target of rapamycin Arabidopsis thaliana 137-140 34761234-4 2021 Exogenous carbon/nitrogen can be supplied to dissect the TOR pathway. Carbon 10-16 target of rapamycin Arabidopsis thaliana 57-60 34835646-2 2021 MnO2/extended graphite exhibited an increase in sp2 carbon bonds in comparison with that of extended graphite. Carbon 52-58 Sp2 transcription factor Homo sapiens 48-51 34819685-2 2021 Due to its important applications in technology, amorphous carbon with sp2 or mixed sp2-sp3 hybridization has been explored and prepared3,4, but synthesis of bulk amorphous carbon with sp3 concentration close to 100% remains a challenge. Carbon 59-65 Sp2 transcription factor Homo sapiens 71-74 34819685-2 2021 Due to its important applications in technology, amorphous carbon with sp2 or mixed sp2-sp3 hybridization has been explored and prepared3,4, but synthesis of bulk amorphous carbon with sp3 concentration close to 100% remains a challenge. Carbon 59-65 Sp3 transcription factor Homo sapiens 185-188 34819685-4 2021 Here, we successfully synthesized millimetre-sized samples-with volumes 103-104 times as large as produced in earlier studies-of transparent, nearly pure sp3 amorphous carbon by heating fullerenes at pressures close to the cage collapse boundary. Carbon 168-174 Sp3 transcription factor Homo sapiens 154-157 34487922-3 2021 Meanwhile, the oxidation of C-18 methyl to carboxyl group forms a 18,20-lactone, and the oxidation of C-14 and C-17 gets a heterocyclic oxygen acrossing rings C and D. Additionly, physalins frequently form an oxygen bridge to connect C-14 to C-27. Carbon 234-235 Bardet-Biedl syndrome 9 Homo sapiens 28-32 34487922-3 2021 Meanwhile, the oxidation of C-18 methyl to carboxyl group forms a 18,20-lactone, and the oxidation of C-14 and C-17 gets a heterocyclic oxygen acrossing rings C and D. Additionly, physalins frequently form an oxygen bridge to connect C-14 to C-27. Carbon 242-243 Bardet-Biedl syndrome 9 Homo sapiens 28-32 34622576-1 2021 NiS1.23 Se0.77 nanosheets closely attached to the internal surface of hollow mesoporous carbon sphere (HMCS) to form a NiS1.23 Se0.77 nanosheets embedded in HMCS (NSSNs@HMCS) composite as the anode of sodium ion batteries (SIBs) is reported by a facile synthesis route. Carbon 88-94 MKKS centrosomal shuttling protein Homo sapiens 103-107 34622576-1 2021 NiS1.23 Se0.77 nanosheets closely attached to the internal surface of hollow mesoporous carbon sphere (HMCS) to form a NiS1.23 Se0.77 nanosheets embedded in HMCS (NSSNs@HMCS) composite as the anode of sodium ion batteries (SIBs) is reported by a facile synthesis route. Carbon 88-94 MKKS centrosomal shuttling protein Homo sapiens 157-161 34622576-1 2021 NiS1.23 Se0.77 nanosheets closely attached to the internal surface of hollow mesoporous carbon sphere (HMCS) to form a NiS1.23 Se0.77 nanosheets embedded in HMCS (NSSNs@HMCS) composite as the anode of sodium ion batteries (SIBs) is reported by a facile synthesis route. Carbon 88-94 MKKS centrosomal shuttling protein Homo sapiens 169-173 34287077-5 2021 Our results showed that when U87- or TLR3-transfected HEK293-TLR7 cells were stimulated with TLR-ligands, such as poly I:C plus LPS or poly I:C plus R837, IFN-beta production was significantly increased with MyD88 inhibition in a dose-dependent manner. Carbon 142-143 IFN1@ Homo sapiens 155-163 34223885-0 2021 Carbon flux around leaf-cytosolic glyceraldehyde-3-phosphate dehydrogenase introduces a 13C signal in plant glucose. Carbon 0-6 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 34-74 34765546-0 2021 Silencing of Fused Toes Homolog (FTS) Increases Radiosensitivity to Carbon-Ion Through Downregulation of Notch Signaling in Cervical Cancer Cells. Carbon 68-74 AKT interacting protein Homo sapiens 13-31 34765546-0 2021 Silencing of Fused Toes Homolog (FTS) Increases Radiosensitivity to Carbon-Ion Through Downregulation of Notch Signaling in Cervical Cancer Cells. Carbon 68-74 AKT interacting protein Homo sapiens 33-36 34765546-0 2021 Silencing of Fused Toes Homolog (FTS) Increases Radiosensitivity to Carbon-Ion Through Downregulation of Notch Signaling in Cervical Cancer Cells. Carbon 68-74 notch receptor 1 Homo sapiens 105-110 34765546-1 2021 The effects of Carbon ion radiation (C-ion) alone or in combination with fused toes homolog (FTS) silencing on Notch signaling were investigated in uterine cervical cancer cell lines (ME180 and CaSki). Carbon 15-21 notch receptor 1 Homo sapiens 111-116 34707193-2 2021 The sp2 carbon atoms adjacent to nitrogen in the pyridine ring provide pi-acceptor which forms a complex with filled d-orbital of native oxides on Cu and Ru metal film. Carbon 8-14 Sp2 transcription factor Homo sapiens 4-7 34398681-7 2021 In contrast, when galactose was the carbon source, reduction in mitochondrial translation was observed predominantly from Cox1 mRNA in Deltairc3rho+ but no defect was observed in irc3 temperature-sensitive cells, at 370C. Carbon 36-42 cytochrome c oxidase subunit 1 Saccharomyces cerevisiae S288C 122-126 34617740-1 2021 The binding of C-4-halogenated 1-(4-X-2,5-dimethoxyphenyl)-2-aminopropane (DOX) serotonin agonist psychedelics at all three 5-HT2 receptor subtypes is up to two orders of magnitude stronger for X = Cl, Br, or I (but not F) than when C-4 bears a hydrogen atom and more than expected from their hydrophobicities. Carbon 233-235 5-hydroxytryptamine receptor 2A Homo sapiens 124-138 34537657-2 2021 C18-CDs are synthesized by simple one-step solvothermal method using octadecylamine and citric acid as carbon sources, and C18-CDs with proper polarity are collected through column chromatography purification. Carbon 103-109 Bardet-Biedl syndrome 9 Homo sapiens 0-3 34768798-9 2021 Under salt stress, alpha-TC demonstrated a stronger regulatory effect on carbon- and nitrogen-related metabolites reorganization and modulation of antioxidant patterns than gamma-TC. Carbon 73-79 centroradiali Arabidopsis thaliana 19-27 34770842-5 2021 Therefore, in the current study, HBx to Bcl-xL is abrogated on high-affinity carbon nanotubes using computational structural biology tools. Carbon 77-83 BCL2 like 1 Homo sapiens 40-46 34627525-0 2021 Thionine-functionalized three-dimensional carbon nanomaterial-based aptasensor for analysis of Abeta oligomers in serum. Carbon 42-48 amyloid beta precursor protein Homo sapiens 95-100 34228132-10 2021 Patients with an insulin adjusted A1C > 9% (hence, not in remission) had higher fasting PI:C ratios. Carbon 91-92 insulin Homo sapiens 17-24 34228132-12 2021 CONCLUSION: Children with new-onset T1D are undergoing progressive beta-cell ER stress and aberrant proinsulin processing as evidenced by increasing PI:C ratios. Carbon 152-153 insulin Homo sapiens 100-110 34597507-1 2021 A set of Pd(II) biladiene complexes bearing different combinations of methyl- and phenyl-substituents on the sp3-hybridized meso-carbon (the 10-position of the biladiene framework) was prepared and studied. Carbon 129-135 Sp3 transcription factor Homo sapiens 109-112 34542146-3 2021 In the design of 4VPCB, one to three carbon atoms are inserted between the positive charge and negative charge (carbon space length, CSL) of the pyridyl-containing side chain to adjust hydration with water molecules. Carbon 37-43 chorionic somatomammotropin hormone like 1 Homo sapiens 133-136 34605631-4 2021 The obtained carbon nanozyme (denoted as HBF-1-C800) displays 3- to 7-fold enhancement on peroxidase (POD) activity compared with the conventional carbon nanozymes and also shows ca. Carbon 13-19 forkhead box G1 Homo sapiens 41-46 34664145-0 2021 Fluorescent paper strip immunoassay with carbon nanodots@silica for determination of human serum amyloid A1. Carbon 41-47 serum amyloid A1 Homo sapiens 91-107 34664145-1 2021 A fluorescent paper strip immunoassay in conjunction with carbon nanodots@silica (CND@SiO2) as a label was developed for the quantitative measurements of human serum amyloid A1 (hSAA1) in serum at clinically significant concentrations for lung cancer diagnosis. Carbon 58-64 serum amyloid A1 Homo sapiens 160-176 34926845-4 2021 Based on these experimental and theoretical results, poly (8AN2SA)/bismuth film glassy carbon modified electrode was further investigated to develop a simple and sensitive electrochemical method for the simultaneous determination of Pb(II) and Cd(II) ions. Carbon 87-93 submaxillary gland androgen regulated protein 3B Homo sapiens 233-239 34664145-1 2021 A fluorescent paper strip immunoassay in conjunction with carbon nanodots@silica (CND@SiO2) as a label was developed for the quantitative measurements of human serum amyloid A1 (hSAA1) in serum at clinically significant concentrations for lung cancer diagnosis. Carbon 58-64 serum amyloid A1 Homo sapiens 178-183 34683725-0 2021 Synthesis of Magnetic Adsorbents Based Carbon Highly Efficient and Stable for Use in the Removal of Pb(II) and Cd(II) in Aqueous Solution. Carbon 39-45 submaxillary gland androgen regulated protein 3B Homo sapiens 100-106 34664145-2 2021 Monodispersed CND@SiO2 was prepared by cohydrolysis between silane-crosslinked carbon nanodots and silica precursors via the Strober method and further attached covalently to anti-hSAA1 (14F8) monoclonal antibody (anti-hSAA1(14F8)) specific to the hSAA1 target. Carbon 79-85 serum amyloid A1 Homo sapiens 180-185 34602194-0 2021 Simple and facile carbon dots based electrochemical biosensor for TNF-alpha targeting in cancer patient"s sample. Carbon 18-24 tumor necrosis factor Homo sapiens 66-75 34683725-7 2021 The adsorption capacity for Pb(II) was 389 mg g-1 (1.88 mmol g-1) and 249 mg g-1 (1.20 mmol g-1); while for Cd(II) was 269 mg g-1 (2.39 mmol g-1) and 264 mg g-1 (2.35 mmol g-1) for the Fe3O4+C and CoFe2O4+C, respectively. Carbon 191-192 submaxillary gland androgen regulated protein 3B Homo sapiens 28-34 34626114-7 2022 Metformin also exhibited antioxidant effects, as it reduced ROS production which is associated with the upregulation of FoxO3a and PGC-1alpha in gut of 6-month-old fish with poly I:C-injection. Carbon 181-182 forkhead box O3 Homo sapiens 120-126 34591476-5 2021 However, compression displays special plastic damages of forming kinklike puckers and sp3-bonded carbon, resulting in a tension-compression asymmetry of DGNs. Carbon 97-103 Sp3 transcription factor Homo sapiens 86-89 34582179-6 2021 Microstructural analysis revealed that the sample contained stable nanostructured inorganics such as crystalline silicon, silicon carbide, and sp3-like carbon. Carbon 152-158 Sp3 transcription factor Homo sapiens 143-146 34592814-4 2021 Density functional theory calculations revealed the involvement of a high-spin FeIV (S = 2) center in the challenging oxidation of the sp3 C-H bond. Carbon 139-140 Sp3 transcription factor Homo sapiens 135-138 34681647-9 2021 Compound 6c-induced DNA damage was characterized by comet assay, p53 phosphorylation, and gammaH2A.X, which was diminished by pretreatment with NAC. Carbon 9-11 tumor protein p53 Homo sapiens 65-68 34626114-9 2022 Taken together, the present study suggested that poly I:C-injection led to aging-like phenomena in gut and metformin activated AMPK and SIRT1 to reduce NF-kappaB mediated inflammation and resist oxidative stress via enhanced expression of FoxO3a and PGC-1alpha, and finally delayed gut aging in vertebrates. Carbon 56-57 forkhead box O3 Homo sapiens 239-245 34626114-9 2022 Taken together, the present study suggested that poly I:C-injection led to aging-like phenomena in gut and metformin activated AMPK and SIRT1 to reduce NF-kappaB mediated inflammation and resist oxidative stress via enhanced expression of FoxO3a and PGC-1alpha, and finally delayed gut aging in vertebrates. Carbon 56-57 PPARG coactivator 1 alpha Homo sapiens 250-260 34626335-1 2022 In order to improve the treatment efficiency of printing and dyeing wastewater, the carbon nanotubes-silver-modified-titanium dioxide (CNTs-Ag-TiO2, CAT) ternary composite was prepared by a mechanical mixing method. Carbon 84-90 catalase Homo sapiens 149-152 34623713-2 2021 Herein, Co is introduced into conductive Cu-catecholate (Cu-CAT) nanorod arrays directly grown on a flexible carbon cloth for hydrogen evolution reaction (HER). Carbon 109-115 catalase Homo sapiens 60-63 34101995-9 2021 The highest H2 mole fraction (51.52%) in gaseous products from the APR process was obtained with Ru/MEC (MEC: mesoporous carbon). Carbon 121-127 C-C motif chemokine ligand 28 Homo sapiens 100-103 34558569-3 2021 In this study, a hollow carbon catalyst, NOC-1000-1, was prepared by pyrolysis of a mixture of a N-enriched Zn/bispyrozolate-based metal-organic framework and urea to replace the labile Pt-based catalysts for ORR. Carbon 24-30 nocturnin Homo sapiens 41-44 34101995-9 2021 The highest H2 mole fraction (51.52%) in gaseous products from the APR process was obtained with Ru/MEC (MEC: mesoporous carbon). Carbon 121-127 C-C motif chemokine ligand 28 Homo sapiens 105-108 34216971-5 2021 The PMS activation process in Co/CoOx@NC/PMS system was dominant by efficient mediation of electron transfer from pollutants to PMS through the sp2-hybridized carbon and nitrogen network. Carbon 159-165 Sp2 transcription factor Homo sapiens 144-147 34634038-8 2021 Consistently with these differential tissue-specific roles, Grain deficient larvae display delayed development on high sugar diet, while showing deregulated central carbon and lipid metabolism primarily on low sugar diet. Carbon 165-171 grain Drosophila melanogaster 60-65 34498296-7 2021 Both the thickness and the sp2 -bonded carbon ratio of the intermediate layer decrease as the annealing temperature increases, which indicates that the amorphous carbon is directly converted into diamond after annealing. Carbon 39-45 Sp2 transcription factor Homo sapiens 27-30 34520201-0 2021 Sr3(CO4)O Antiperovskite with Tetrahedrally Coordinated sp3-Hybridized Carbon and OSr6 Octahedra. Carbon 71-77 Sp3 transcription factor Canis lupus familiaris 56-59 34520201-2 2021 Single-crystal diffraction shows the presence of (CO4)4- groups, i.e., sp3-hybridized carbon tetrahedrally coordinated by covalently bound oxygen atoms. Carbon 86-92 Sp3 transcription factor Canis lupus familiaris 71-74 34498296-7 2021 Both the thickness and the sp2 -bonded carbon ratio of the intermediate layer decrease as the annealing temperature increases, which indicates that the amorphous carbon is directly converted into diamond after annealing. Carbon 162-168 Sp2 transcription factor Homo sapiens 27-30 34294343-5 2021 Cyclic voltammetric study of CSB modified glassy carbon electrode exhibits 2e-/2H+ transfer reaction in phosphate buffered saline electrolyte following a surface-confined process with a correlation coefficient of 0.99. Carbon 49-55 ERCC excision repair 6, chromatin remodeling factor Homo sapiens 29-32 34139039-1 2021 Elovl5 elongates fatty acids with 18 carbon atoms and in cooperation with other enzymes guarantees the normal levels of very long-chain fatty acids, which are necessary for a proper membrane structure. Carbon 37-43 ELOVL family member 5, elongation of long chain fatty acids (yeast) Mus musculus 0-6 34289180-1 2021 The aim of this study was to evaluate, in a case-control design, the association between maternal genotypes for variants in 23 genes involved in folate/one-carbon metabolism and nonsyndromic cleft lip with or without cleft palate (NSCL/P) in a Chilean population. Carbon 156-162 nescient helix-loop-helix 1 Homo sapiens 231-235 34516111-1 2021 By facilitating the chemical conversion of thiols to thiosulfonates, phosphoramidite/phosphite bearing sp3-hybridized carbon serves as an ideal coupling material to forge new connections at room temperature. Carbon 118-124 Sp3 transcription factor Homo sapiens 103-106 34227061-3 2021 SCA type 34 (SCA34) is caused by mutations in ELOVL4 (ELOngation of Very Long-chain fatty acids 4), a fatty acid elongase essential for biosynthesis of Very Long Chain Saturated and Polyunsaturated Fatty Acids (VLC-SFA and VLC-PUFA, resp., >=28 carbons), which have important functions in the brain, skin, retina, Meibomian glands, testes, and sperm. Carbon 245-252 ELOVL fatty acid elongase 4 Homo sapiens 13-18 34227061-3 2021 SCA type 34 (SCA34) is caused by mutations in ELOVL4 (ELOngation of Very Long-chain fatty acids 4), a fatty acid elongase essential for biosynthesis of Very Long Chain Saturated and Polyunsaturated Fatty Acids (VLC-SFA and VLC-PUFA, resp., >=28 carbons), which have important functions in the brain, skin, retina, Meibomian glands, testes, and sperm. Carbon 245-252 ELOVL fatty acid elongase 4 Rattus norvegicus 46-52 34500180-9 2021 These findings highlight that combining distal geomorphic and hydrologic drivers can be effective in determining the relationship between riverine CH4 and the proximal controls (e.g., nutrients, dissolved oxygen, dissolved organic carbon), as well as in identifying their key drivers. Carbon 231-237 COP9 signalosome subunit 4 Drosophila melanogaster 147-150 34215136-2 2021 We report here a dual-signal electrochemical immunosensor for detecting carcinoembryonic antigen (CEA) using multi-wall carbon nanotubes (MWCNTs)-cobalt phosphide (CoP) as an electrocatalytic label. Carbon 120-126 CEA cell adhesion molecule 3 Homo sapiens 72-96 34215136-2 2021 We report here a dual-signal electrochemical immunosensor for detecting carcinoembryonic antigen (CEA) using multi-wall carbon nanotubes (MWCNTs)-cobalt phosphide (CoP) as an electrocatalytic label. Carbon 120-126 CEA cell adhesion molecule 3 Homo sapiens 98-101 34681389-0 2021 Interaction of Carbon Dots from Grilled Spanish Mackerel with Human Serum Albumin, gamma-Globulin and Fibrinogen. Carbon 15-21 albumin Homo sapiens 68-81 34681389-0 2021 Interaction of Carbon Dots from Grilled Spanish Mackerel with Human Serum Albumin, gamma-Globulin and Fibrinogen. Carbon 15-21 fibrinogen beta chain Homo sapiens 83-112 34608406-3 2022 Herein, we propose an innovative implantation strategy to fabricate a multi-walled carbon nanotube/polyvinyl alcohol (MWCNT/PVA, MCP) interpenetrating interface to achieve flexibility, anti-damage, and non-contact sensing electronic skin (E-skin). Carbon 83-89 CD46 molecule Homo sapiens 129-132 34533316-0 2021 A Three-Dimensional sp2 Carbon-Conjugated Covalent Organic Framework. Carbon 24-30 Sp2 transcription factor Homo sapiens 20-23 34533316-1 2021 A first example of an sp2 carbon-conjugated three-dimensional (3D) covalent organic framework (COF) (BUCT-COF-4) is synthesized via the Knoevenagel condensation of the saddle-shaped aldehyde-substituted cyclooctatetrathiophene and 1,4-phenylenediacetonitrile. Carbon 26-32 Sp2 transcription factor Homo sapiens 22-25 34533316-3 2021 After it is doped with iodine, the material not only exhibits an enhanced electron mobility up to 2.62 cm2 V-1 s-1 in ambient air but also presents an unexpected metal-free ferromagnetic phase transition arising from the formation of aligned spins unidirectional across the whole sp2 carbon-conjugated 3D framework. Carbon 284-290 Sp2 transcription factor Homo sapiens 280-283 34631798-5 2021 SERBP1 regulates One-carbon metabolism and epigenetic modification of histones, and increased SERBP1 expression in cancers such as leukemia, ovarian, prostate, liver and glioblastoma is correlated with poor patient outcomes. Carbon 21-27 SERPINE1 mRNA binding protein 1 Homo sapiens 0-6 34498624-2 2021 Here, a new strategy, involving a free radical reaction pathway initiated by AIBN, was used to construct the benzylic sp3 C-SCN bond. Carbon 122-123 Sp3 transcription factor Homo sapiens 118-121 34375537-0 2022 Black carbon induces complement activation via NLRP3 inflammasome in human corneal epithelial cells. Carbon 6-12 NLR family pyrin domain containing 3 Homo sapiens 47-52 34639973-9 2021 It was shown that the oxidized zone (sp2/sp3 hybrid carbon) of each nanocomposite sample was enlarged by forming the nanocomposite compared to the corresponding original GO sample. Carbon 52-58 Sp2 transcription factor Homo sapiens 37-40 34639973-9 2021 It was shown that the oxidized zone (sp2/sp3 hybrid carbon) of each nanocomposite sample was enlarged by forming the nanocomposite compared to the corresponding original GO sample. Carbon 52-58 Sp3 transcription factor Homo sapiens 41-44 34683849-0 2021 Quantifying Cytosolic Cytochrome c Concentration Using Carbon Quantum Dots as a Powerful Method for Apoptosis Detection. Carbon 55-61 cytochrome c, somatic Homo sapiens 22-34 34683849-7 2021 RESULTS: Carbon quantum dots were synthesized and were successfully employed for Cyt c detection by means of fluorescence microscopy. Carbon 9-15 cytochrome c, somatic Homo sapiens 81-86 34683850-1 2021 Human serum albumin (HSA) is efficiently taken up by cancer cells as a source of carbon and energy. Carbon 81-87 albumin Homo sapiens 6-19 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 153-159 Sp2 transcription factor Homo sapiens 79-82 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 153-159 Sp3 transcription factor Homo sapiens 101-104 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 0-6 Sp2 transcription factor Homo sapiens 79-82 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 0-6 Sp3 transcription factor Homo sapiens 101-104 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 153-159 Sp3 transcription factor Homo sapiens 227-230 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 0-6 Sp3 transcription factor Homo sapiens 227-230 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 0-6 Sp2 transcription factor Homo sapiens 235-238 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 153-159 Sp2 transcription factor Homo sapiens 235-238 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 206-212 Sp2 transcription factor Homo sapiens 79-82 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 206-212 Sp3 transcription factor Homo sapiens 101-104 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 206-212 Sp3 transcription factor Homo sapiens 227-230 34684910-1 2021 Carbon nanomaterials with a different character of the chemical bond-graphene (sp2) and nanodiamond (sp3)-are the building bricks for a new class of all-carbon hybrid nanomaterials, where the two different carbon networks with sp3 and sp2 hybridization coexist, interacting and even transforming into one another. Carbon 206-212 Sp2 transcription factor Homo sapiens 235-238 34263532-1 2021 A new practical method for construction of 3D porous carbon was developed through molecular design via one step synthesis from commercially available carbon tetrabromide and bis(trimethylsilyl)acetylene on a gram-scale, and the obtained porous carbon has well-defined sp 1 -sp 3 all-carbon structure (C 13 ), high stability and also high surface area. Carbon 53-59 Sp3 transcription factor Homo sapiens 274-278 34323377-0 2021 The role of oxygenic groups and sp3 carbon hybridization in activated graphite electrodes for vanadium redox flow batteries. Carbon 36-42 Sp3 transcription factor Homo sapiens 32-35 34263532-1 2021 A new practical method for construction of 3D porous carbon was developed through molecular design via one step synthesis from commercially available carbon tetrabromide and bis(trimethylsilyl)acetylene on a gram-scale, and the obtained porous carbon has well-defined sp 1 -sp 3 all-carbon structure (C 13 ), high stability and also high surface area. Carbon 244-250 Sp3 transcription factor Homo sapiens 274-278 34538293-3 2021 This new detector is based on a thin carbon foil positioned on the front panel of a conventional MCP-DLD detector. Carbon 37-43 CD46 molecule Homo sapiens 97-100 34324779-3 2021 sp 2 - and sp-hybridized carbon nucleophiles were found to be competent initiators for this cascade, giving arylated or alkynylated products, respectively. Carbon 25-31 Sp2 transcription factor Homo sapiens 0-4 34616406-6 2021 Mechanistically, MAT2A modulates HIV-1 latency through S-Adenosylmethionine (SAM)-mediated one-carbon flux. Carbon 95-101 methionine adenosyltransferase 2A Homo sapiens 17-22 34616406-9 2021 Overall, this study reveals an important role of MAT2A-mediated one-carbon metabolism in regulating HIV-1 latency and provides a promising target for the development of new strategies for a functional cure of HIV-1. Carbon 68-74 methionine adenosyltransferase 2A Homo sapiens 49-54 34324316-2 2021 The absolute stereochemistry of the major ring-closed form of the dicarboxylic acid at the newly formed sp3 carbon atoms was determined to be (S,S) by the process of docking simulation of the diarylethene molecule and HSA followed by molecular dynamics calculations and comparison of the measured and calculated CD spectra. Carbon 108-114 Sp3 transcription factor Homo sapiens 104-107 34280615-0 2021 Pan2-Pan3 complex, together with Ccr4-Not complex, has a role in the cell growth on non-fermentable carbon sources. Carbon 100-106 Pan3p Saccharomyces cerevisiae S288C 5-9 34280615-5 2021 Ccr4, Pan2, and Pan3 were phosphorylated in GlyLac medium, suggesting that the activities of Ccr4, Pan2, and Pan3 may be regulated by phosphorylation in response to change of carbon sources. Carbon 175-181 Pan3p Saccharomyces cerevisiae S288C 16-20 34280615-5 2021 Ccr4, Pan2, and Pan3 were phosphorylated in GlyLac medium, suggesting that the activities of Ccr4, Pan2, and Pan3 may be regulated by phosphorylation in response to change of carbon sources. Carbon 175-181 Pan3p Saccharomyces cerevisiae S288C 109-113 34280615-7 2021 Our results suggest that the Pan2-Pan3 complex, together with the Ccr4-Not complex, has important roles in the growth on non-fermentable carbon sources. Carbon 137-143 Pan3p Saccharomyces cerevisiae S288C 34-38 34482874-0 2021 Simultaneous sensing gamma-glutamyl transpeptidase and alkaline phosphatase by robust dual-emission carbon dots. Carbon 100-106 alkaline phosphatase, placental Homo sapiens 55-75 34528965-1 2021 Fully pi-conjugated sp2 carbon covalent organic frameworks upon integration with carboxylic electrolyte sites on the pore wall become highly luminescent sensors. Carbon 24-30 Sp2 transcription factor Homo sapiens 20-23 34125990-1 2021 The direct and indirect electrochemical grafting of alkyl halides (RX) and aryl halides (ArX) on carbon, metal and polymer surfaces is examined. Carbon 97-103 aristaless related homeobox Homo sapiens 89-92 34382056-2 2021 The transformation was initiated by non-activated sp2 C-S bond cleavage along with consecutive alkyne insertions. Carbon 54-55 Sp2 transcription factor Homo sapiens 50-53 34254710-3 2021 The resulting helical chiral bicyclic architecture consist exclusively of sp 2 hybridized carbon atoms. Carbon 90-96 Sp2 transcription factor Homo sapiens 74-78 34102366-1 2021 We prepared a single-atom Fe catalyst supported on an oxygen-doped, nitrogen-rich carbon support (SAFe-OCN) for degrading a broad spectrum of contaminants of emerging concern (CECs) by activating peroxides such as peroxymonosulfate (PMS). Carbon 82-88 bone gamma-carboxyglutamate protein Homo sapiens 103-106 34571785-7 2021 Moreover, MPL+Poly I:C combination enhanced ovalbumin-specific serum IgG, IgG1, and IgG2c production and proliferative function of CD4 and CD8 T cells after in vitro ovalbumin peptide stimulation. Carbon 21-22 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 44-53 34313361-2 2021 Here, we utilize the Schottky barrier-induced surface electric field, by the construction of high density of electron-deficient Ni nanoparticles inside nitrogen-rich carbons, to facilitate the enrichment and fixation of all NO x - anions on the electrode surface, including NO 3 - and NO 2 - , and thus ensure the final selectivity to NH 3 . Carbon 166-173 NBL1, DAN family BMP antagonist Homo sapiens 274-278 34604658-11 2021 Oxidized domains at the irregular edges of the graphene layers, due to a broken, non-pristine sp2 carbon network, allow for adsorption of polar molecules. Carbon 98-104 Sp2 transcription factor Homo sapiens 94-97 34196706-5 2021 Moreover, we showed that the downstream signaling, e.g. STAT1 phosphorylation and IRF1 expression, was upregulated to a greater extent after high LET carbon-ion irradiation than X-rays, and that IRF1 upregulation was also ATR dependent. Carbon 150-156 interferon regulatory factor 1 Homo sapiens 82-86 34196706-5 2021 Moreover, we showed that the downstream signaling, e.g. STAT1 phosphorylation and IRF1 expression, was upregulated to a greater extent after high LET carbon-ion irradiation than X-rays, and that IRF1 upregulation was also ATR dependent. Carbon 150-156 ATR serine/threonine kinase Homo sapiens 222-225 34382981-3 2021 The aliphatic H-atom abstraction (HAA) vs. electrophilic aromatic substitution (EAS) steps are responsible for the sp3 vs. sp2 C-H amination site-selectivity and a larger steric congestion disfavors sp2 EAS, thus resulting in Fe-catalyzed site-selectivity toward sp3 C-H amination. Carbon 127-128 Sp3 transcription factor Homo sapiens 115-118 34382981-3 2021 The aliphatic H-atom abstraction (HAA) vs. electrophilic aromatic substitution (EAS) steps are responsible for the sp3 vs. sp2 C-H amination site-selectivity and a larger steric congestion disfavors sp2 EAS, thus resulting in Fe-catalyzed site-selectivity toward sp3 C-H amination. Carbon 127-128 Sp2 transcription factor Homo sapiens 123-126 34382981-3 2021 The aliphatic H-atom abstraction (HAA) vs. electrophilic aromatic substitution (EAS) steps are responsible for the sp3 vs. sp2 C-H amination site-selectivity and a larger steric congestion disfavors sp2 EAS, thus resulting in Fe-catalyzed site-selectivity toward sp3 C-H amination. Carbon 127-128 Sp3 transcription factor Homo sapiens 263-266 34263536-8 2021 Importantly, we isolated a rhodium eta 5 -cyclohexadienyl complex intermediate with an sp 3 -hybridized carbon bearing both the nucleophile and the leaving group. Carbon 104-110 Sp3 transcription factor Homo sapiens 87-91 34568657-0 2021 First-Principles Calculations for Adsorption of HF, COF2, and CS2 on Pt-Doped Single-Walled Carbon Nanotubes. Carbon 92-98 chorionic somatomammotropin hormone 2 Homo sapiens 62-65 34568657-2 2021 In this paper, the gas sensitivity of Pt doped on (8, 0) single-walled carbon nanotube (SWCNT) to HF, CS2, and COF2 is investigated based on density functional theory. Carbon 71-77 chorionic somatomammotropin hormone 2 Homo sapiens 102-105 34180113-0 2021 Enzymatic Tailoring in Luzopeptin Biosynthesis Involves Cytochrome P450-Mediated Carbon-Nitrogen Bond Desaturation for Hydrazone Formation. Carbon 81-87 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 56-71 34622194-7 2021 Mechanistic in vivo toxicity analysis showed a reduction in oxidative stress in carbon-modified alpha-Fe2O3 exposed zebrafish embryos compared to Fe3O4 due to despaired influential atomic interaction with sod1 protein along with significant less morphological abnormalities and apoptosis. Carbon 80-86 superoxide dismutase 1, soluble Danio rerio 205-209 34479402-3 2021 Geminal disubstitution at the Calpha carbon in gamma2,2 led to unfavorable steric contacts, disabling its accommodation in the alphagamma C12 hairpin nucleating turn unlike the gamma3,3 and gamma4,4 residues. Carbon 37-43 tryptophanyl-tRNA synthetase 1 Homo sapiens 47-55 34399575-2 2021 Many substrates including sp2 and sp3 C-H substrates were well tolerated, furnishing the corresponding products in good yields. Carbon 38-39 Sp3 transcription factor Homo sapiens 34-37 34219331-4 2021 The B=C double bond in compound 5b adds carbon dioxide, CS2, sulfur dioxide, phenyl isocyanate, an acetylene ester or two NO molecules to give the corresponding four-membered ring annulated heterocycles. Carbon 6-7 chorionic somatomammotropin hormone 2 Homo sapiens 56-59 34180113-3 2021 Significantly, we revealed a multitasking cytochrome P450 enzyme that catalyzes four consecutive oxidations including the highly unusual carbon-nitrogen bond desaturation, forming the hydrazone-bearing 4-OH-Thp residues. Carbon 137-143 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 42-57 34244329-10 2021 CONCLUSIONS: Distinct from previously reported predictors of GFR decline in type 2 diabetes, these findings suggest differential incorporation of FFAs at the sn1 carbon of the phospholipids" glycerol backbone as an independent predictor of rapid GFR decline in T1D. Carbon 162-168 solute carrier family 38 member 3 Homo sapiens 158-161 34512346-9 2021 Adiponectin (3-30 microg ml-1) and AdipoRon (25-50 muM) markedly inhibited the LPS- and poly (I:C)-induced release of Tumor Necrosis Factor-alpha, IL-6 and chemokines (CCL3, CCL4, CCL5, CXCL1, CXCL8, CXCL10) and the IL-4-induced release of chemokines (CCL13, CCL17, CCL22) in a concentration-dependent manner. Carbon 96-98 adiponectin, C1Q and collagen domain containing Homo sapiens 0-11 34383978-10 2021 Finally, RanBPM deficient cells displayed enhanced glycolysis and deregulated central carbon metabolism. Carbon 86-92 RAN binding protein 9 Homo sapiens 9-15 34061465-3 2021 These macrophages were pretreated with rigosertib and then induced with LPS or poly I:C. RESULTS: Rigosertib suppressed LPS or poly I:C-induced expression of inflammatory cytokines (tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and IL-23) in WT bone marrow-derived macrophages while failed to affect the upregulation of TNF-alpha and IL-6 in LPS-treated bone marrow-derived macrophages from MEK1DD mice. Carbon 134-135 tumor necrosis factor Mus musculus 182-209 34061465-3 2021 These macrophages were pretreated with rigosertib and then induced with LPS or poly I:C. RESULTS: Rigosertib suppressed LPS or poly I:C-induced expression of inflammatory cytokines (tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and IL-23) in WT bone marrow-derived macrophages while failed to affect the upregulation of TNF-alpha and IL-6 in LPS-treated bone marrow-derived macrophages from MEK1DD mice. Carbon 134-135 tumor necrosis factor Mus musculus 211-220 34061465-3 2021 These macrophages were pretreated with rigosertib and then induced with LPS or poly I:C. RESULTS: Rigosertib suppressed LPS or poly I:C-induced expression of inflammatory cytokines (tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and IL-23) in WT bone marrow-derived macrophages while failed to affect the upregulation of TNF-alpha and IL-6 in LPS-treated bone marrow-derived macrophages from MEK1DD mice. Carbon 134-135 interleukin 6 Mus musculus 226-239 34061465-3 2021 These macrophages were pretreated with rigosertib and then induced with LPS or poly I:C. RESULTS: Rigosertib suppressed LPS or poly I:C-induced expression of inflammatory cytokines (tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and IL-23) in WT bone marrow-derived macrophages while failed to affect the upregulation of TNF-alpha and IL-6 in LPS-treated bone marrow-derived macrophages from MEK1DD mice. Carbon 134-135 interleukin 6 Mus musculus 241-245 34494634-3 2021 As an important graphene derivate, graphane, which is composed of entirely sp3 hybridized carbon atoms and possesses the characteristic of non-wrinkle in contrast to graphene, provides an ideal two-dimensional platform to rigidify crown ether molecules. Carbon 90-96 Sp3 transcription factor Homo sapiens 75-78 34501015-7 2021 The dependence of sp3 fraction in carbon films on the substrate bias voltage achieves a high consistency within the experiment results. Carbon 34-40 Sp3 transcription factor Homo sapiens 18-21 34501044-1 2021 Three-dimensional graphene foam (3D-GrFoam) is a highly porous structure and sustained lattice formed by graphene layers with sp2 and sp3 hybridized carbon. Carbon 149-155 Sp3 transcription factor Homo sapiens 134-137 34514258-1 2021 To improve the condensed-phase reaction rate of epsilon-CL-20, polydopamine (PDA)-nickel complex-coated multiwalled carbon nanotubes (CNTs) have been prepared and used as combustion catalysts. Carbon 116-122 epithelial membrane protein 1 Homo sapiens 56-61 34115276-1 2021 A facile and green strategy was carried out for the preparation of fluorescent carbon nanoparticles (CNp) using non-toxic circassian seeds as carbon precursor (CNp, named ACNp). Carbon 79-85 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 101-104 34115276-1 2021 A facile and green strategy was carried out for the preparation of fluorescent carbon nanoparticles (CNp) using non-toxic circassian seeds as carbon precursor (CNp, named ACNp). Carbon 79-85 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 160-163 34115276-1 2021 A facile and green strategy was carried out for the preparation of fluorescent carbon nanoparticles (CNp) using non-toxic circassian seeds as carbon precursor (CNp, named ACNp). Carbon 142-148 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 101-104 34115276-1 2021 A facile and green strategy was carried out for the preparation of fluorescent carbon nanoparticles (CNp) using non-toxic circassian seeds as carbon precursor (CNp, named ACNp). Carbon 142-148 2',3'-cyclic nucleotide 3' phosphodiesterase Homo sapiens 160-163 34514258-7 2021 Also, under the effect of the carbon-based catalyst, the HNCO formation was detected at another temperature in comparison with raw CL-20, with peak absorption at 224.1 vs 232.3 C and the evolution was completed at 250.8 vs 246.2 C, respectively. Carbon 30-36 epithelial membrane protein 1 Homo sapiens 131-136 34433820-2 2021 The inner space circumfused by sp2-carbon networks can also encapsulate diamondoid molecules to afford sp2/sp3-hybrid nanocarbon peapods that have recently emerged as unique nanostructures. Carbon 35-41 Sp2 transcription factor Homo sapiens 31-34 34433820-2 2021 The inner space circumfused by sp2-carbon networks can also encapsulate diamondoid molecules to afford sp2/sp3-hybrid nanocarbon peapods that have recently emerged as unique nanostructures. Carbon 35-41 Sp2 transcription factor Homo sapiens 103-106 34433820-2 2021 The inner space circumfused by sp2-carbon networks can also encapsulate diamondoid molecules to afford sp2/sp3-hybrid nanocarbon peapods that have recently emerged as unique nanostructures. Carbon 35-41 Sp3 transcription factor Homo sapiens 107-110 34512346-9 2021 Adiponectin (3-30 microg ml-1) and AdipoRon (25-50 muM) markedly inhibited the LPS- and poly (I:C)-induced release of Tumor Necrosis Factor-alpha, IL-6 and chemokines (CCL3, CCL4, CCL5, CXCL1, CXCL8, CXCL10) and the IL-4-induced release of chemokines (CCL13, CCL17, CCL22) in a concentration-dependent manner. Carbon 96-98 tumor necrosis factor Homo sapiens 118-145 34380317-1 2021 Covalent functionalization of single-walled carbon nanotubes (SWCNTs) with organic molecules results in red-shifted emissive states associated with sp3-defects in the tube lattice, which facilitate their improved optical functionality, including single-photon emission. Carbon 44-50 Sp3 transcription factor Homo sapiens 148-151 34415446-1 2021 This study harnesses the power of mobile data in developing a spatial model for predicting black carbon (BC) concentrations within one of the most heavily populated regions in the Middle East and North Africa MENA region, Greater Cairo Region (GCR) in Egypt. Carbon 97-103 ENAH actin regulator Homo sapiens 209-213 34443939-0 2021 Laser Scribing Fabrication of Graphitic Carbon Biosensors for Label-Free Detection of Interleukin-6. Carbon 40-46 interleukin 6 Homo sapiens 86-99 34443939-3 2021 Here we present an electrochemical immunosensor platform based on the use of highly porous graphitic carbon electrodes fabricated by direct laser writing of commercial polyimide tapes and chemically modified with capture IL-6 antibodies. Carbon 101-107 interleukin 6 Homo sapiens 221-225 34407113-1 2021 This study aimed to investigate the structure of two deciduous forests and assess their above-ground carbon stock in order to promote community forest management (CFM) for REDD+ opportunities in the Ban Mae Chiang Rai Lum Community Forest in northern Thailand. Carbon 101-107 lumican Homo sapiens 218-221 34402428-6 2021 Functional genomics further reveal that KLF10 target genes are primarily involved in central carbon metabolism. Carbon 93-99 Kruppel-like factor 10 Mus musculus 40-45 34328724-0 2021 Co-assembly of Peptides and Carbon Nanodots: Sensitive Analysis of Transglutaminase 2. Carbon 28-34 transglutaminase 2 Homo sapiens 67-85 34477791-1 2021 Graphdiyne oxide (GDYO) is a carbon-based nanomaterial possessing sp2 and sp-hybridized carbon atoms with many promising applications. Carbon 29-35 Sp2 transcription factor Homo sapiens 66-69 34311457-3 2021 According to structural characteristics, strong pi-pi interactions existed between carbon materials and PEDOT: PSS, and PEDOT: PSS layers with organized and arranged morphology were easier templated by GNS than GQD or MWCNT. Carbon 83-89 PSS Homo sapiens 111-114 34443113-1 2021 Graphene, a two-dimensional nanosheet, is composed of carbon species (sp2 hybridized carbon atoms) and is the center of attention for researchers due to its extraordinary physicochemical (e.g., optical transparency, electrical, thermal conductivity, and mechanical) properties. Carbon 54-60 Sp2 transcription factor Homo sapiens 70-73 34443113-1 2021 Graphene, a two-dimensional nanosheet, is composed of carbon species (sp2 hybridized carbon atoms) and is the center of attention for researchers due to its extraordinary physicochemical (e.g., optical transparency, electrical, thermal conductivity, and mechanical) properties. Carbon 85-91 Sp2 transcription factor Homo sapiens 70-73 34339216-3 2021 Commercially available copper thiophene-2-carboxylate (CuTc, 2 mol %) as catalyst promoted the diazidation of both pi and sigma C-C bonds within 10 min in the presence of readily available oxidants and trimethylsilyl azide. Carbon 128-129 cutC copper transporter Homo sapiens 55-59 34320322-2 2021 Calix(3)pyrrole, a tripyrrolic porphyrinogen-like macrocycle bearing three sp3-carbon linkages, is a missing link molecule that might hold the key to this enigma; however, it has remained elusive. Carbon 79-85 Sp3 transcription factor Homo sapiens 75-78 34339216-3 2021 Commercially available copper thiophene-2-carboxylate (CuTc, 2 mol %) as catalyst promoted the diazidation of both pi and sigma C-C bonds within 10 min in the presence of readily available oxidants and trimethylsilyl azide. Carbon 130-131 cutC copper transporter Homo sapiens 55-59 34343498-6 2021 SELW promoted purine salvage pathways and inhibited one-carbon metabolism by recruiting an E3 ubiquitin ligase, tripartite motif-containing protein 21, which controlled the stability of serine hydroxymethyltransferase 2. Carbon 56-62 selenoprotein W Homo sapiens 0-4 34343498-6 2021 SELW promoted purine salvage pathways and inhibited one-carbon metabolism by recruiting an E3 ubiquitin ligase, tripartite motif-containing protein 21, which controlled the stability of serine hydroxymethyltransferase 2. Carbon 56-62 tripartite motif containing 21 Homo sapiens 112-150 34443398-0 2021 Magnetic Nitrogen-Doped Porous Carbon Nanocomposite for Pb(II) Adsorption from Aqueous Solution. Carbon 31-37 submaxillary gland androgen regulated protein 3B Homo sapiens 56-62 34376745-8 2021 Overall it appears nematode abundance, diversity and contribution to belowground carbon cycling is stronger at lower elevations and gradually keep declining towards higher elevations under temperate vegetation cover in Banihal-pass of Pir-Panjal mountain range. Carbon 81-87 pirin Homo sapiens 235-238 34391473-8 2021 Stimulation with the TLR2, 3 and 4 agonists Pam3CSK4, Poly I:C and LPS, respectively, induced the pro-inflammatory cytokines TNF-alpha and IL-8, while the TLR5 agonist FliC only induced TNF-alpha. Carbon 61-62 tumor necrosis factor Equus caballus 125-134 34391473-8 2021 Stimulation with the TLR2, 3 and 4 agonists Pam3CSK4, Poly I:C and LPS, respectively, induced the pro-inflammatory cytokines TNF-alpha and IL-8, while the TLR5 agonist FliC only induced TNF-alpha. Carbon 61-62 tumor necrosis factor Equus caballus 186-195 34236859-4 2021 The process begins with regioselective trapping of a 3-trifloxybenzyne intermediate by an O-silyl phosphite in an Abramov-like reaction to bond the strained Csp carbons with phosphorus and silicon. Carbon 161-168 DnaJ heat shock protein family (Hsp40) member C5 Homo sapiens 157-160 34370789-9 2021 These results indicate that Rex plays a key role in GBS pathogenicity by modulating virulence factor gene expression and carbon metabolism to harvest nutrients from the host. Carbon 121-127 rex Mus musculus 28-31 34370789-1 2021 In many Gram-positive bacteria, the redox-sensing transcriptional repressor Rex controls central carbon and energy metabolism by sensing the intra cellular balance between the reduced and oxidized forms of nicotinamide adenine dinucleotide; the NADH/NAD+ ratio. Carbon 97-103 rex Mus musculus 76-79 34251216-0 2021 Chirality of the Conformation Attacks the Planarity of the sp2 Carbon Atom in a Covalent Bond. Carbon 63-69 Sp2 transcription factor Homo sapiens 59-62 34255970-1 2021 The correlation of the rotation about the Calpha-C" bond and the pyramidalization of the sp2-hybridized carbon atom C" and its three bonding partners to a flattened tetrahedron in the substructure Cbeta-CalphaH-C"( O)-OMe of substituted methyl acetates revealed that the two processes are not independent of each other but parts of a common molecular motion, as outlined in the preceding back-to-back paper. Carbon 104-110 Sp2 transcription factor Homo sapiens 89-92 34255970-1 2021 The correlation of the rotation about the Calpha-C" bond and the pyramidalization of the sp2-hybridized carbon atom C" and its three bonding partners to a flattened tetrahedron in the substructure Cbeta-CalphaH-C"( O)-OMe of substituted methyl acetates revealed that the two processes are not independent of each other but parts of a common molecular motion, as outlined in the preceding back-to-back paper. Carbon 116-117 Sp2 transcription factor Homo sapiens 89-92 34259288-2 2021 In this work, an amorphous carbon core-shell-coated PbTe nanostructure prepared by a "bottom-up" method is first incorporated into the Sn1-ySbyTe matrix to enhance the thermoelectric performance of SnTe. Carbon 27-33 solute carrier family 38 member 3 Homo sapiens 135-138 34297574-0 2021 Scalable High-Pressure Synthesis of sp2-sp3 Carbon Nanoribbon via (4 + 2) Polymerization of 1,3,5-Triethynylbenzene. Carbon 44-50 Sp2 transcription factor Homo sapiens 36-39 34297574-0 2021 Scalable High-Pressure Synthesis of sp2-sp3 Carbon Nanoribbon via (4 + 2) Polymerization of 1,3,5-Triethynylbenzene. Carbon 44-50 Sp3 transcription factor Homo sapiens 40-43 34297574-2 2021 Here by introducing ethynyl to phenyl, we obtained a sp2-sp3 carbon nanoribbon structure by compressing 1,3,5-triethynylbenzene (TEB), and the reaction pressure of phenyl was successfully decreased to 4 GPa, which is the lowest reaction pressure of aromatics at room temperature. Carbon 61-67 Sp2 transcription factor Homo sapiens 53-56 34297574-2 2021 Here by introducing ethynyl to phenyl, we obtained a sp2-sp3 carbon nanoribbon structure by compressing 1,3,5-triethynylbenzene (TEB), and the reaction pressure of phenyl was successfully decreased to 4 GPa, which is the lowest reaction pressure of aromatics at room temperature. Carbon 61-67 Sp3 transcription factor Homo sapiens 57-60 34170704-2 2021 The GAs of C-H (1330.9 +- 10.0 kJ mol-1) and N-H (1361.5 +- 10.5 kJ mol-1) deprotonated sites of bifunctional barbituric acid were determined from the selective production of their corresponding heterodimers. Carbon 11-12 PAXIP1 associated glutamate rich protein 1 Homo sapiens 4-7 34269570-7 2021 MAEBC did not correlate with the modified combustion efficiency but positively correlated with the ratio of organic carbon (OC) to elemental carbon (EC) and negatively correlated with char-EC. Carbon 116-122 bone gamma-carboxyglutamate protein Homo sapiens 124-126 34269570-7 2021 MAEBC did not correlate with the modified combustion efficiency but positively correlated with the ratio of organic carbon (OC) to elemental carbon (EC) and negatively correlated with char-EC. Carbon 149-151 bone gamma-carboxyglutamate protein Homo sapiens 124-126 34212211-0 2021 Nitrogen-doped carbon quantum dots fabricated from cellulolytic enzyme lignin and its application to the determination of cytochrome c and trypsin. Carbon 15-21 cytochrome c, somatic Homo sapiens 122-134 34212211-1 2021 A sensitive and effective strategy for the detection of cytochrome c (Cyt c) and trypsin was developed using biomass nitrogen-doped carbon quantum dots (N-CQDs) as the fluorescence probe. Carbon 132-138 cytochrome c, somatic Homo sapiens 56-68 34212211-1 2021 A sensitive and effective strategy for the detection of cytochrome c (Cyt c) and trypsin was developed using biomass nitrogen-doped carbon quantum dots (N-CQDs) as the fluorescence probe. Carbon 132-138 cytochrome c, somatic Homo sapiens 70-75 34270870-4 2021 Herein, for the first time, the design of a high-performance stand-alone carbyne film comprised of sp/sp2 -hybridized carbon as an electrode for AC filtering under a wide frequency range is reported. Carbon 118-124 Sp2 transcription factor Homo sapiens 102-105 34246169-3 2021 To overcome these two key drawbacks, a novel Ti-based IMAC nanomaterial was prepared by Ti-bonded beta-cyclodextrin (beta-CD) anchored on the surface of carbon nanotubes (CNTs) (denoted as COOH-CNTs-CD-Ti) and successfully applied as a biofunctional adsorbent for selectively enriching trace phosphopeptides. Carbon 153-159 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 117-124 34098343-7 2021 Moreover, Toll-like receptor-3 (TLR-3) mRNA and protein levels in HD11 treated with Poly (I: C) were markedly increased compared to those of HD11 not treated with Poly (I: C). Carbon 93-95 toll like receptor 3 Gallus gallus 10-37 34410440-3 2021 Consequently, DERA enzymes can be applied in C-C bond formation reactions to produce novel compounds, thus offering a versatile biocatalytic alternative for synthesis. Carbon 45-46 deoxyribose-phosphate aldolase Homo sapiens 14-18 34410440-3 2021 Consequently, DERA enzymes can be applied in C-C bond formation reactions to produce novel compounds, thus offering a versatile biocatalytic alternative for synthesis. Carbon 47-48 deoxyribose-phosphate aldolase Homo sapiens 14-18 34410440-11 2021 KEY POINTS: DERA aldolases are versatile biocatalysts able to make new C-C bonds. Carbon 73-74 deoxyribose-phosphate aldolase Homo sapiens 14-18 34410440-11 2021 KEY POINTS: DERA aldolases are versatile biocatalysts able to make new C-C bonds. Carbon 75-76 deoxyribose-phosphate aldolase Homo sapiens 14-18 34240721-2 2021 Based on the Horner-Wadsworth-Emmons reaction, the condensation polymerization for the formation of an sp2 carbon-linkage can be achieved at room temperature. Carbon 107-113 Sp2 transcription factor Homo sapiens 103-106 34359734-0 2021 Involvement of HIF-1alpha in the Detection, Signaling, and Repair of DNA Double-Strand Breaks after Photon and Carbon-Ion Irradiation. Carbon 111-117 hypoxia inducible factor 1 subunit alpha Homo sapiens 15-25 34359734-2 2021 Hypoxia combined with photon and carbon ion irradiation (C-ions) stabilizes HIF-1alpha. Carbon 33-39 hypoxia inducible factor 1 subunit alpha Homo sapiens 76-86 34240721-5 2021 This new synthesis method provides a facile means to prepare attractive sp2 carbon linked porous organic frameworks. Carbon 76-82 Sp2 transcription factor Homo sapiens 72-75 34250537-0 2021 Stabilizing Na metal anode with NaF interface on spent cathode carbon from aluminum electrolysis. Carbon 63-69 C-X-C motif chemokine ligand 8 Homo sapiens 32-35 34250537-1 2021 We report the synthesis of spent cathode carbon (SCC) with a NaF interface from aluminum electrolysis, and its application as a Na metal anode host. Carbon 41-47 C-X-C motif chemokine ligand 8 Homo sapiens 61-64 34260202-4 2021 Through the fine-tuning of D2-symmetric chiral amidoporphyrins as the supporting ligands, the Co(II)-catalyzed radical cascade process, which proceeds in a single operation under mild conditions, enables asymmetric construction of multisubstituted cyclopropane-fused tetrahydrofurans bearing three contiguous stereogenic centers, including two all-carbon quaternary centers, in high yields with excellent stereoselectivities. Carbon 348-354 mitochondrially encoded cytochrome c oxidase II Homo sapiens 94-100 34275271-0 2021 Selective Interface Synthesis of Cobalt Metaphosphate Nanosheet Arrays Motivated by Functionalized Carbon Cloths for Fast and Durable Na/K-Ion Storage. Carbon 99-105 Fas activated serine/threonine kinase Homo sapiens 117-121 34264662-6 2021 Density functional theory calculations revealed a mechanism involving PdH formation and migratory insertion into the alkene, followed by C-C bond formation. Carbon 137-138 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 70-73 34264662-6 2021 Density functional theory calculations revealed a mechanism involving PdH formation and migratory insertion into the alkene, followed by C-C bond formation. Carbon 139-140 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 70-73 34242035-2 2021 Herein, we present two-dimensional carbon-based nanomaterials-graphdiyne oxide (GDYO) nanosheets that interact with an intracellular protein corona consisting of signal transducer and activator of transcription 3 (STAT3), inducing the reeducation of immunosuppressive macrophages. Carbon 35-41 signal transducer and activator of transcription 3 Homo sapiens 162-212 34242035-2 2021 Herein, we present two-dimensional carbon-based nanomaterials-graphdiyne oxide (GDYO) nanosheets that interact with an intracellular protein corona consisting of signal transducer and activator of transcription 3 (STAT3), inducing the reeducation of immunosuppressive macrophages. Carbon 35-41 signal transducer and activator of transcription 3 Homo sapiens 214-219 34259296-2 2021 The bulky gem-dimethyl (gdm) substituent on carbons adjacent to the t-amide sidechain either at Calpha (glycyl) or Cbeta/Cgamma (aminoethylene) sides may influence the Z/E rotamer ratio arising from a restricted rotation around the t-amide bond. Carbon 44-51 amyloid beta precursor protein Homo sapiens 199-200 34712839-4 2021 More specifically, we targeted dCas9-VPR toward binding sites of Gcr1-Gcr2 and Tye7 present in several promoters of genes encoding enzymes engaged in the central carbon metabolism. Carbon 162-168 Gcr2p Saccharomyces cerevisiae S288C 70-74 34264072-4 2021 This approach has been validated in our study of CoII/CoI redox transformation for Co tetraphenylporphyrin (CoTPP) immobilized on carbon cloth and multiwalled carbon nanotubes (CNTs) - one of the most active heterogeneous molecular catalysts in carbon dioxide (CO2) electroreduction. Carbon 130-136 mitochondrially encoded cytochrome c oxidase II Homo sapiens 49-53 34264072-4 2021 This approach has been validated in our study of CoII/CoI redox transformation for Co tetraphenylporphyrin (CoTPP) immobilized on carbon cloth and multiwalled carbon nanotubes (CNTs) - one of the most active heterogeneous molecular catalysts in carbon dioxide (CO2) electroreduction. Carbon 159-165 mitochondrially encoded cytochrome c oxidase II Homo sapiens 49-53 34372071-13 2021 The chemical structure of the PU-CNT composite has shown a degree of agglomeration under disruption of the sp2 carbon structure. Carbon 111-117 Sp2 transcription factor Homo sapiens 107-110 34712839-4 2021 More specifically, we targeted dCas9-VPR toward binding sites of Gcr1-Gcr2 and Tye7 present in several promoters of genes encoding enzymes engaged in the central carbon metabolism. Carbon 162-168 Tye7p Saccharomyces cerevisiae S288C 79-83 34232013-2 2021 Herein, in situ synthesis of nano-GeP confined in nitrogen-doped carbon (GeP@NC) fibers was designed and performed via coaxial electrospinning followed by a phosphating process. Carbon 65-71 granulin precursor Homo sapiens 34-37 34361269-1 2021 Silicon oxycarbides synthesized through a conventional polymeric route show characteristic nanodomains that consist of sp2 hybridized carbon, tetrahedrally coordinated SiO4, and tetrahedrally coordinated silicon with carbon substitution for oxygen, called "mixed bonds." Carbon 134-140 Sp2 transcription factor Homo sapiens 119-122 34372300-4 2021 In this study, carbon electrode with electrodeposited NiO nanoparticles was selected as a suitable electrode material for insulin determination. Carbon 15-21 insulin Homo sapiens 122-129 34443737-3 2021 The prepared Ch-ACs were tested for the removal of Cr(VI) and Pb(II) at different pH, initial metal ions concentration, time, activated carbon dosage, and temperature. Carbon 136-142 submaxillary gland androgen regulated protein 3B Homo sapiens 62-68 34361580-2 2021 The physical properties of the synthesized oil palm trunk activated carbon (OPTAC) were analyzed by SEM, FTIR-ATR, and XRD. Carbon 68-74 ATR serine/threonine kinase Homo sapiens 110-113 34232013-2 2021 Herein, in situ synthesis of nano-GeP confined in nitrogen-doped carbon (GeP@NC) fibers was designed and performed via coaxial electrospinning followed by a phosphating process. Carbon 65-71 granulin precursor Homo sapiens 73-76 34290319-1 2021 In the present article, we developed a highly sensitive label-free electrochemical immunosensor based on NiFe-layered double hydroxides (LDH)/reduced graphene oxide (rGO)/gold nanoparticles modified glassy carbon electrode for the determination of receptor tyrosine kinase-like orphan receptor (ROR)-1. Carbon 206-212 receptor tyrosine kinase like orphan receptor 1 Homo sapiens 248-301 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 61-67 AKT serine/threonine kinase 1 Homo sapiens 212-215 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 61-67 forkhead box O1 Homo sapiens 217-222 34337195-1 2021 Nanodiamond (ND) is a class of carbon nanomaterial with covalently connected sp3 carbon atoms in its core and an sp2 carbon adorned surface via edge defects or doping. Carbon 31-37 Sp3 transcription factor Homo sapiens 77-80 34285189-4 2021 Therefore, we aimed to investigate the involvement of radiosensitivity, cell death modalities and p53 status in response to carbon-ion radiation (CIR) here. Carbon 124-130 tumor protein p53 Homo sapiens 98-101 34181425-0 2021 Atom Transfer Radical Polymerization-Inspired Room Temperature (sp3)C-N Coupling. Carbon 68-69 Sp3 transcription factor Homo sapiens 64-67 34522314-1 2021 Graphite and related sp2 carbons are ubiquitous electrode materials with particular promise for use in e.g., energy storage and desalination devices, but very little is known about the properties of the carbon-electrolyte double layer at technologically relevant concentrations. Carbon 25-32 Sp2 transcription factor Homo sapiens 21-24 34242391-6 2021 Accordingly, a small-molecule PAR2 inhibitor suppressed poly(I:C)/thrombin-induced leukocyte-endothelial adhesion, cytokine production, and endothelial tissue factor expression. Carbon 63-65 coagulation factor II, thrombin Homo sapiens 66-74 34260932-1 2021 CINV1, converting sucrose into glucose and fructose, is a key entry of carbon into cellular metabolism, and HXK1 functions as a pivotal sensor for glucose. Carbon 71-77 cytosolic invertase 1 Arabidopsis thaliana 0-5 34337195-1 2021 Nanodiamond (ND) is a class of carbon nanomaterial with covalently connected sp3 carbon atoms in its core and an sp2 carbon adorned surface via edge defects or doping. Carbon 31-37 Sp2 transcription factor Homo sapiens 113-116 34337195-1 2021 Nanodiamond (ND) is a class of carbon nanomaterial with covalently connected sp3 carbon atoms in its core and an sp2 carbon adorned surface via edge defects or doping. Carbon 81-87 Sp3 transcription factor Homo sapiens 77-80 34337195-1 2021 Nanodiamond (ND) is a class of carbon nanomaterial with covalently connected sp3 carbon atoms in its core and an sp2 carbon adorned surface via edge defects or doping. Carbon 117-123 Sp2 transcription factor Homo sapiens 113-116 34308050-0 2021 Polyethyleneimine-Functionalized Carbon Nanotube/Graphene Oxide Composite: A Novel Sensing Platform for Pb(II) Acetate in Aqueous Solution. Carbon 33-39 submaxillary gland androgen regulated protein 3B Homo sapiens 104-110 34299056-7 2021 In conclusion, we demonstrate here that TIGAR is upregulated in stimulated human lymphocytes through the PI3K/AKT signaling pathway, which contributes to the redirection of the carbon flux to the PPP. Carbon 177-183 AKT serine/threonine kinase 1 Homo sapiens 110-113 34157699-3 2021 As graphene oxide (GO) and its derivatives naturally possess a mixture of sp3 and sp2 Carbon atoms, it is pertinent to look at them as potential candidates for Ovchinnikov ferromagnetism. Carbon 86-92 Sp2 transcription factor Homo sapiens 82-85 34157699-7 2021 The evolution of magnetic moment with sp3/sp2Carbons can be utilized in Carbon based spintronic applications. Carbon 72-78 Sp3 transcription factor Homo sapiens 38-41 34138569-3 2021 Intriguingly, the C atom arrangement reveals multiple structure evolution behavior with increased carbon content, from isolated anions in Na4C, tetramers in Na3C2, extended chains in NaC, pentagonal rings in Na2C3, to eventually hexagonal rings in NaC2. Carbon 98-104 NACC family member 2 Homo sapiens 248-252 34277562-1 2021 Herein, selenium and nitrogen co-doped carbon quantum dots (Se/N-CQDs) were hydrothermally synthesized by using citric acid, histidine, and sodium selenite, which had sp3 and sp2 hybridized carbon atoms and showed excitation-dependent fluorescence behavior. Carbon 39-45 Sp3 transcription factor Homo sapiens 167-170 34277562-1 2021 Herein, selenium and nitrogen co-doped carbon quantum dots (Se/N-CQDs) were hydrothermally synthesized by using citric acid, histidine, and sodium selenite, which had sp3 and sp2 hybridized carbon atoms and showed excitation-dependent fluorescence behavior. Carbon 39-45 Sp2 transcription factor Homo sapiens 175-178 34277562-1 2021 Herein, selenium and nitrogen co-doped carbon quantum dots (Se/N-CQDs) were hydrothermally synthesized by using citric acid, histidine, and sodium selenite, which had sp3 and sp2 hybridized carbon atoms and showed excitation-dependent fluorescence behavior. Carbon 190-196 Sp2 transcription factor Homo sapiens 175-178 34488320-8 2021 The expression of NSE, MAP2 and beta-tubulin increased significantly in the C, L and CL groups compared to the control group (P<0.001), where the CL group had the highest expression among the groups (7.59+-0.126, 7.87+-0.191, 6.36+-0.420, respectively, (P<0.01)). Carbon 76-77 enolase 2 Homo sapiens 18-21 34412196-2 2021 A recent quantum study of carbon in the 10-70 Gbar range and at a temperature of 100 eV used N-atom density functional theory (DFT) with N~32-64 and molecular dynamics (MD). Carbon 26-32 adaptor related protein complex 1 associated regulatory protein Homo sapiens 46-50 34137582-0 2021 Imaging-Guided Chemo-Photothermal Polydopamine Carbon Dots for EpCAM-Targeted Delivery toward Liver Tumor. Carbon 47-53 epithelial cell adhesion molecule Homo sapiens 63-68 34197026-2 2021 Herein, fluorescent single-walled carbon nanotubes (SWCNT) are used for the recognition and real-time quantification of insulin. Carbon 34-40 insulin Homo sapiens 120-127 34072492-0 2021 Ion-Enhanced Etching Characteristics of sp2-Rich Hydrogenated Amorphous Carbons in CF4 Plasmas and O2 Plasmas. Carbon 72-79 Sp2 transcription factor Homo sapiens 40-43 34268314-14 2021 The developmental timing-specific and incoherent fluctuation among folate adducts and increased expression of mthfd1L in response to FD reflect the context-dependent regulation of folate-mediated one-carbon metabolism, endowing the larvae to prioritize the essential biochemical pathways for supporting the continuous growth in response to folate depletion. Carbon 200-206 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Danio rerio 110-117 34278147-7 2021 It was also suggested that an unexpected interaction between the ester protecting group at the 3-position of the selenofuranose ring and the anomeric carbon atom decreases the alpha/beta selectivity. Carbon 150-156 amyloid beta precursor protein Homo sapiens 176-186 34249061-0 2021 Level of Sulfite Oxidase Activity Affects Sulfur and Carbon Metabolism in Arabidopsis. Carbon 53-59 sulfite oxidase Arabidopsis thaliana 9-24 34249061-2 2021 It was also demonstrated that SO activity is essential to cope with rising dark-induced endogenous sulfite levels and maintain optimal carbon and sulfur metabolism in tomato plants exposed to extended dark stress. Carbon 135-141 sulfite oxidase Solanum lycopersicum 30-32 34249061-3 2021 The response of SO and sulfite reductase to direct exposure of low and high levels of sulfate and carbon was rarely shown. Carbon 98-104 sulfite oxidase Solanum lycopersicum 16-18 34124878-0 2021 Synergistic Effect of Co(III) and Co(II) in a 3D Structured Co3O4/Carbon Felt Electrode for Enhanced Electrochemical Nitrate Reduction Reaction. Carbon 66-72 mitochondrially encoded cytochrome c oxidase III Homo sapiens 22-29 34124878-0 2021 Synergistic Effect of Co(III) and Co(II) in a 3D Structured Co3O4/Carbon Felt Electrode for Enhanced Electrochemical Nitrate Reduction Reaction. Carbon 66-72 mitochondrially encoded cytochrome c oxidase II Homo sapiens 34-40 34145842-1 2021 OBJECTIVE: To investigate the effects of multi-walled carbon nanotubes (MWCNTs) with different length or chemical modification on endothelial cell activation and to explore the role of nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3) inflammasome. Carbon 54-60 interferon activated gene 208 Mus musculus 248-273 34111025-0 2021 Carbon nanotubes (CNT)-loaded ginsenosides Rb3 suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer. Carbon 0-6 CD274 molecule Sus scrofa 67-72 34277092-9 2021 However, higher levels of carbon (C) have been observed in DCIR lesions. Carbon 26-32 C-type lectin domain family 4 member A Homo sapiens 59-63 34199478-0 2021 Comparison of Physicochemical Properties of Fly Ash Precursor, Na-P1(C) Zeolite-Carbon Composite and Na-P1 Zeolite-Adsorption Affinity to Divalent Pb and Zn Cations. Carbon 80-86 Nucleosome assembly protein 1 Drosophila melanogaster 63-68 34206920-1 2021 In this work, an electrochemically activated screen-printed carbon electrode modified with sodium dodecyl sulfate (aSPCE/SDS) was proposed for the simultaneous determination of paracetamol (PA), diclofenac (DF), and tramadol (TR). Carbon 60-66 coagulation factor II thrombin receptor Homo sapiens 226-228 34081471-5 2021 However, the rate-determining step of the SN1 pathway has changed from the chloride-leaving step to the C-C bond-formation step. Carbon 104-105 solute carrier family 38 member 3 Homo sapiens 42-45 34081471-5 2021 However, the rate-determining step of the SN1 pathway has changed from the chloride-leaving step to the C-C bond-formation step. Carbon 106-107 solute carrier family 38 member 3 Homo sapiens 42-45 34128643-5 2021 Our findings show that sp2 carbon in the polycyclic aromatic precursor can be converted to sp3 carbon under unexpectedly moderate temperature conditions by using nanoscale precursors and thus offer a low-temperature approach for the synthesis of sub-4 nm nanodiamonds. Carbon 27-33 Sp2 transcription factor Homo sapiens 23-26 34128643-5 2021 Our findings show that sp2 carbon in the polycyclic aromatic precursor can be converted to sp3 carbon under unexpectedly moderate temperature conditions by using nanoscale precursors and thus offer a low-temperature approach for the synthesis of sub-4 nm nanodiamonds. Carbon 27-33 Sp3 transcription factor Homo sapiens 91-94 34128643-5 2021 Our findings show that sp2 carbon in the polycyclic aromatic precursor can be converted to sp3 carbon under unexpectedly moderate temperature conditions by using nanoscale precursors and thus offer a low-temperature approach for the synthesis of sub-4 nm nanodiamonds. Carbon 95-101 Sp2 transcription factor Homo sapiens 23-26 34128643-5 2021 Our findings show that sp2 carbon in the polycyclic aromatic precursor can be converted to sp3 carbon under unexpectedly moderate temperature conditions by using nanoscale precursors and thus offer a low-temperature approach for the synthesis of sub-4 nm nanodiamonds. Carbon 95-101 Sp3 transcription factor Homo sapiens 91-94 34200740-4 2021 The effectiveness of the surface modification of carbon nonwoven fabrics was confirmed by the FTIR method using an ATR device. Carbon 49-55 ATR serine/threonine kinase Homo sapiens 115-118 34194668-0 2021 Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms? Carbon 70-76 chorionic somatomammotropin hormone 2 Homo sapiens 30-33 34194668-10 2021 Indeed, the ability of this enzyme to convert CS2 could represent an alternative source of carbon acquisition for diatoms, in addition to CO2. Carbon 91-97 chorionic somatomammotropin hormone 2 Homo sapiens 46-49 34243540-7 2021 For glassy carbon compressed to ~30 GPa, the previously unknown bulk modulus was found to be equal to K0 = 28 (2) GPa (K" = 5.5(5)). Carbon 11-17 glycophorin A (MNS blood group) Homo sapiens 114-117 34072492-1 2021 The sp2-rich hydrogenated amorphous carbon (a-C:H) is widely adopted as hard masks in semiconductor-device fabrication processes. Carbon 36-42 Sp2 transcription factor Homo sapiens 4-7 34070648-3 2021 Specific chemical functionalities (-COO, -NH2 and -S) on the thiol precursor (L-cysteine ethyl ester) were clicked directly on the sp2 carbon of graphene framework with grafting density of 1 unit L-cysteine per 113 carbon atoms on graphene. Carbon 135-141 Sp2 transcription factor Homo sapiens 131-134 34113268-0 2021 Genetic and Metabolite Variability in One-Carbon Metabolism Applied to an Insulin Resistance Model in Patients With Schizophrenia Receiving Atypical Antipsychotics. Carbon 42-48 insulin Homo sapiens 74-81 34241183-1 2021 Carbon-carbon coupling is an important step in many catalytic reactions, and performing sp3-sp3 carbon-carbon coupling heterogeneously is particularly challenging. Carbon 0-6 Sp3 transcription factor Homo sapiens 88-91 34241183-1 2021 Carbon-carbon coupling is an important step in many catalytic reactions, and performing sp3-sp3 carbon-carbon coupling heterogeneously is particularly challenging. Carbon 0-6 Sp3 transcription factor Homo sapiens 92-95 34241183-1 2021 Carbon-carbon coupling is an important step in many catalytic reactions, and performing sp3-sp3 carbon-carbon coupling heterogeneously is particularly challenging. Carbon 7-13 Sp3 transcription factor Homo sapiens 88-91 34241183-1 2021 Carbon-carbon coupling is an important step in many catalytic reactions, and performing sp3-sp3 carbon-carbon coupling heterogeneously is particularly challenging. Carbon 7-13 Sp3 transcription factor Homo sapiens 92-95 34241183-1 2021 Carbon-carbon coupling is an important step in many catalytic reactions, and performing sp3-sp3 carbon-carbon coupling heterogeneously is particularly challenging. Carbon 96-102 Sp3 transcription factor Homo sapiens 88-91 34241183-1 2021 Carbon-carbon coupling is an important step in many catalytic reactions, and performing sp3-sp3 carbon-carbon coupling heterogeneously is particularly challenging. Carbon 96-102 Sp3 transcription factor Homo sapiens 92-95 34241183-1 2021 Carbon-carbon coupling is an important step in many catalytic reactions, and performing sp3-sp3 carbon-carbon coupling heterogeneously is particularly challenging. Carbon 103-109 Sp3 transcription factor Homo sapiens 88-91 34241183-1 2021 Carbon-carbon coupling is an important step in many catalytic reactions, and performing sp3-sp3 carbon-carbon coupling heterogeneously is particularly challenging. Carbon 103-109 Sp3 transcription factor Homo sapiens 92-95 34241183-3 2021 Herein, we extend this study to NiAu SAAs and find that Ni atoms in Au are active for C-I cleavage and selective sp3-sp3 carbon-carbon coupling to produce ethane. Carbon 121-127 Sp3 transcription factor Homo sapiens 113-116 34241183-3 2021 Herein, we extend this study to NiAu SAAs and find that Ni atoms in Au are active for C-I cleavage and selective sp3-sp3 carbon-carbon coupling to produce ethane. Carbon 121-127 Sp3 transcription factor Homo sapiens 117-120 34241183-3 2021 Herein, we extend this study to NiAu SAAs and find that Ni atoms in Au are active for C-I cleavage and selective sp3-sp3 carbon-carbon coupling to produce ethane. Carbon 128-134 Sp3 transcription factor Homo sapiens 113-116 34241183-3 2021 Herein, we extend this study to NiAu SAAs and find that Ni atoms in Au are active for C-I cleavage and selective sp3-sp3 carbon-carbon coupling to produce ethane. Carbon 128-134 Sp3 transcription factor Homo sapiens 117-120 34241183-7 2021 These simulations shed light on the mechanism of this important sp3-sp3 carbon-carbon coupling chemistry on SAAs. Carbon 72-78 Sp3 transcription factor Homo sapiens 64-67 34241183-7 2021 These simulations shed light on the mechanism of this important sp3-sp3 carbon-carbon coupling chemistry on SAAs. Carbon 72-78 Sp3 transcription factor Homo sapiens 68-71 34241183-7 2021 These simulations shed light on the mechanism of this important sp3-sp3 carbon-carbon coupling chemistry on SAAs. Carbon 79-85 Sp3 transcription factor Homo sapiens 64-67 34241183-7 2021 These simulations shed light on the mechanism of this important sp3-sp3 carbon-carbon coupling chemistry on SAAs. Carbon 79-85 Sp3 transcription factor Homo sapiens 68-71 34073198-7 2021 Scale-up of PHA production is limited due to the cost of the carbon source metabolized by the microorganisms. Carbon 61-67 lamin B receptor Homo sapiens 12-15 34064734-2 2021 In this work, a cost-effective synthesis strategy for nitrogen and oxygen co-doped porous carbon (NOC) from petroleum sludge waste was developed. Carbon 90-96 nocturnin Homo sapiens 98-101 34063705-0 2021 High-Sensitivity Dual-Probe Detection of Urinary miR-141 in Cancer Patients via a Modified Screen-Printed Carbon Electrode-Based Electrochemical Biosensor. Carbon 106-112 microRNA 141 Homo sapiens 49-56 34068529-1 2021 Graphene is a two-dimensional sp2 hybridized carbon material that has attracted tremendous attention for its stimuli-responsive applications, owing to its high surface area and excellent electrical, optical, thermal, and mechanical properties. Carbon 45-51 Sp2 transcription factor Homo sapiens 30-33 34334796-3 2021 These observations reveal that the cyanopolyyne peak of TMC-1, which is the prototype of cold dark cloud rich in carbon chains, contains also O-bearing complex organic molecules like HCOOCH3 and CH3OCH3, which have been previously seen in a handful of cold interstellar clouds. Carbon 113-119 transmembrane channel like 1 Homo sapiens 56-61 34249601-2 2021 The present publication shows for the first time the application of a facile one-step bottom-up wet-spinning approach for the continuous fabrication of stable and flexible tubular poly(3,4-ethylene dioxythiophene) (PEDOT : PSS) and PEDOT : PSS/carbon nanotube (CNT) hollow fibers. Carbon 244-250 PSS Homo sapiens 240-243 34227765-9 2021 Carbon-based adsorbents of the Chinese stilbene polymer porous microspheres GDX series, GDX-101, GDX-102, GDX-103, GDX-105, and GDX-203, can facilitate thermal desorption below 270 C, which is the maximum tolerance temperature for series 1 and 2, thus providing evidence for the feasibility of using these adsorbents for the thermal adsorption/desorption of dioxins. Carbon 0-6 ubiquitin like 4A Homo sapiens 76-79 34062754-5 2021 On the basis of structural analyses, a model of the microstructure of a-C:H that consists of sp2 and sp3-bonded carbon clusters, hydrogen atoms and dangling bonds was built. Carbon 72-73 Sp2 transcription factor Homo sapiens 93-96 34062754-5 2021 On the basis of structural analyses, a model of the microstructure of a-C:H that consists of sp2 and sp3-bonded carbon clusters, hydrogen atoms and dangling bonds was built. Carbon 72-73 Sp3 transcription factor Homo sapiens 101-104 34062754-5 2021 On the basis of structural analyses, a model of the microstructure of a-C:H that consists of sp2 and sp3-bonded carbon clusters, hydrogen atoms and dangling bonds was built. Carbon 112-118 Sp3 transcription factor Homo sapiens 101-104 34163643-4 2021 In the presence of a third fac-positioned open coordination site, the P-C bond formation was found to be reversible, as shown for a series of molybdenum complexes. Carbon 72-73 FA complementation group C Homo sapiens 27-30 34168784-1 2021 Bimolecular nucleophilic substitution (SN2) reactions at carbon center are well known to proceed with the stereospecific Walden-inversion mechanism. Carbon 57-63 solute carrier family 38 member 5 Homo sapiens 39-42 34927822-1 2021 Conical carbon, specifically multi-walled carbon nanocones (CNCs) and single-walled carboncones, is a new class of sp2 -hybridized carbon allotrope, in addition to fullerene, carbon nanotubes (CNTs), and graphene. Carbon 8-14 Sp2 transcription factor Homo sapiens 115-118 34927822-1 2021 Conical carbon, specifically multi-walled carbon nanocones (CNCs) and single-walled carboncones, is a new class of sp2 -hybridized carbon allotrope, in addition to fullerene, carbon nanotubes (CNTs), and graphene. Carbon 42-48 Sp2 transcription factor Homo sapiens 115-118 34927822-1 2021 Conical carbon, specifically multi-walled carbon nanocones (CNCs) and single-walled carboncones, is a new class of sp2 -hybridized carbon allotrope, in addition to fullerene, carbon nanotubes (CNTs), and graphene. Carbon 131-137 Sp2 transcription factor Homo sapiens 115-118 34435060-0 2021 Evaluation of TNF Family Gene Expression under the Influence of Single-Walled and Multi-Walled Carboxylated Carbon Nanotubes in Jurkat Cell Line and Rat. Carbon 108-114 tumor necrosis factor Homo sapiens 14-17 35405503-5 2022 Here, an electrochemical aptasensor on screen-printed carbon electrode (SPCE) was developed for non-invasive simultaneous real-time detection of glucose and insulin in saliva. Carbon 54-60 insulin Homo sapiens 157-164 35635968-3 2022 The BP-CdTe QDs modified glassy carbon electrode (GCE) firstly captured the anti-Abeta1, and then the target Abeta. Carbon 32-38 amyloid beta precursor protein Homo sapiens 109-114 35523353-3 2022 Fe(III) was anchored in nitrogen-coordinated pots (Fe-Nx) in the sp2-hybridized carbon network, and graphitic-N could synergistically boost the catalysis. Carbon 80-86 Sp2 transcription factor Homo sapiens 65-68 35429555-5 2022 In this study, we found that the light absorption ability of WSOC treated with PS1 was higher than that of PS2 due to the extinction of suspended particles (e.g., black carbon) with particle size between 0.20 mum and 0.45 mum, although the concentrations of WSOC treated with PS1 and PS2 were very close. Carbon 169-175 taste 2 receptor member 64 pseudogene Homo sapiens 284-287 35245753-2 2022 Herein, a novel electrochemical sensor was firstly fabricated based on the beta-cyclodextrin (beta-CD) functionalized carbon nanosheets@carbon nanotubes (CNS@CNT) for the CBZ determination. Carbon 118-124 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 94-101 35429555-5 2022 In this study, we found that the light absorption ability of WSOC treated with PS1 was higher than that of PS2 due to the extinction of suspended particles (e.g., black carbon) with particle size between 0.20 mum and 0.45 mum, although the concentrations of WSOC treated with PS1 and PS2 were very close. Carbon 169-175 taste 2 receptor member 64 pseudogene Homo sapiens 107-110 35461117-3 2022 The Abeta was rapidly recognized using the fluorescent emitter-nitrogen-doped carbon nanodots (N-CDs) under the regulation of BP nanosheets, while the N-CDs alone cannot recognize Abeta without the introduction of BP. Carbon 78-84 amyloid beta precursor protein Homo sapiens 4-9 35636096-5 2022 Finally, the molecular docking analysis implied that the carbonyl and hydroxy groups at the C-11/C-6" of 5 and 6 had a good binding affinity with ERK. Carbon 92-93 mitogen-activated protein kinase 1 Homo sapiens 146-149 35245753-2 2022 Herein, a novel electrochemical sensor was firstly fabricated based on the beta-cyclodextrin (beta-CD) functionalized carbon nanosheets@carbon nanotubes (CNS@CNT) for the CBZ determination. Carbon 136-142 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 94-101 35490797-4 2022 Hence, hydrolysis of ethenyloxirane occurs by competing SN2 attack at C-2 and C-3 in 3:1 ratio, with no SN1 component. Carbon 70-71 solute carrier family 38 member 5 Homo sapiens 56-59 35395301-9 2022 The weighted response ratio of Pn and relationships of Pn with other associated paramerters under insect and pathogen disturbance will facilitate vegetation models to integrate the effects of biotic disturbance on primary production, improving predicition of the ecosystem carbon cyling in combining with leaf area measurement. Carbon 273-279 U6 snRNA biogenesis phosphodiesterase 1 Homo sapiens 31-33 35395301-9 2022 The weighted response ratio of Pn and relationships of Pn with other associated paramerters under insect and pathogen disturbance will facilitate vegetation models to integrate the effects of biotic disturbance on primary production, improving predicition of the ecosystem carbon cyling in combining with leaf area measurement. Carbon 273-279 U6 snRNA biogenesis phosphodiesterase 1 Homo sapiens 55-57 35381514-2 2022 In this study, a new carboxylated carbon nanotube/chitosan aerogel (CCNT/CA) with switchable wettability was developed as a smart adsorbent for fast oil absorption and oil recovery. Carbon 34-40 cyclin T1 Homo sapiens 68-72 35417747-0 2022 Poly I:C and R848 facilitate nitric oxide production via inducible nitric oxide synthase in chicks. Carbon 7-8 nitric oxide synthase 2 Gallus gallus 57-88 35490797-9 2022 The corresponding reaction of rac.-2-methyl-2-ethenyloxirane gave diastereoisomeric adducts, (R, S)- and (S, S)-N-(2-hydroxy-2-methyl-3-buten-1-yl)-l-valine methyl ester, from SN2 attack of the valine amino solely at C-3. Carbon 217-218 solute carrier family 38 member 5 Homo sapiens 176-179 35490797-4 2022 Hence, hydrolysis of ethenyloxirane occurs by competing SN2 attack at C-2 and C-3 in 3:1 ratio, with no SN1 component. Carbon 78-79 solute carrier family 38 member 5 Homo sapiens 56-59 35621880-0 2022 Ratiometric fluorescence enzyme-linked immunosorbent assay based on carbon dots@SiO2@CdTe quantum dots with dual functionalities for alpha-fetoprotein. Carbon 68-74 alpha fetoprotein Homo sapiens 133-150 35192819-2 2022 Under a feast and famine regime, an uncoupled carbon (C) and nitrogen (N)-feeding strategy may be adopted by dosing the C-source at the beginning of the feast and the N-source at the beginning of the famine in order to stimulate a PHA storage response and microbial growth. Carbon 46-52 lamin B receptor Homo sapiens 231-234 35247814-3 2022 Herein, three carbon dots (CDs1 to CDs3) decorated modified-carbon nitride (CDs1-NCN, CDs2-NCN and CDs3-NCN) were designed and fabricated, which show diverse activity of H2O2 photoproduction. Carbon 14-20 motile sperm domain containing 3 Homo sapiens 35-39 35247814-3 2022 Herein, three carbon dots (CDs1 to CDs3) decorated modified-carbon nitride (CDs1-NCN, CDs2-NCN and CDs3-NCN) were designed and fabricated, which show diverse activity of H2O2 photoproduction. Carbon 14-20 motile sperm domain containing 3 Homo sapiens 99-103 35621880-2 2022 Herein, we innovatively constructed a new ratiometric fluorescence enzyme-linked immunosorbent assay (RF-ELISA) for the screening of alpha-fetoprotein (AFP) in early hepatocellular carcinoma in vitro diagnostics using carbon dots@SiO2@CdTe quantum dots (CDs@SiO2@CdTe QDs). Carbon 218-224 alpha fetoprotein Homo sapiens 133-150 35621880-2 2022 Herein, we innovatively constructed a new ratiometric fluorescence enzyme-linked immunosorbent assay (RF-ELISA) for the screening of alpha-fetoprotein (AFP) in early hepatocellular carcinoma in vitro diagnostics using carbon dots@SiO2@CdTe quantum dots (CDs@SiO2@CdTe QDs). Carbon 218-224 alpha fetoprotein Homo sapiens 152-155 35253932-2 2022 These enzymes have been shown to catalyze chemically challenging reactions such as methyl transfer to sp2 - and sp3 -hybridized carbon atoms. Carbon 128-134 Sp2 transcription factor Homo sapiens 102-105 35255332-2 2022 Electrically conductive carbon nanofibers (CNF) were used as bacterial scaffolds to facilitate electron transfer between EAB and Pb(II). Carbon 24-30 submaxillary gland androgen regulated protein 3B Homo sapiens 129-135 35253932-2 2022 These enzymes have been shown to catalyze chemically challenging reactions such as methyl transfer to sp2 - and sp3 -hybridized carbon atoms. Carbon 128-134 Sp3 transcription factor Homo sapiens 112-115 34993786-2 2022 The system was equipped with a carbon felt air diffusion cathode (GDE) and a Ti/IrO2 anode doped with SnO2 (DSA). Carbon 31-37 amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase Homo sapiens 66-69 35486713-5 2022 The crystal structure also revealed unusual fusions in the macrocyclic framework and the presence of one sp3 carbon that disrupts the pi-electron delocalization. Carbon 109-115 Sp3 transcription factor Homo sapiens 105-108 35580274-9 2022 This coordination alters the hybridization character of the ylidic carbon atom, with the greatest change toward sp2 character found for lithium-ion coordination. Carbon 67-73 Sp2 transcription factor Homo sapiens 112-115 35302413-10 2022 Poly I:C altered IL-6 and TGF-beta gene expression in aMSCs from both healthy and CKD cats when compared with the same cells in standard culture. Carbon 7-8 transforming growth factor alpha Felis catus 26-34 35199881-0 2022 Long Term Monitoring of an In Situ Activated Carbon Treatment to Reduce PCB Availability in an Active Harbor. Carbon 45-51 pyruvate carboxylase Homo sapiens 72-75 35468314-1 2022 The location of the phloem deep inside the plant, the high hydrostatic pressure in the phloem, and the composition of phloem sap, which is rich in sugar with a high C:N ratio, allows phloem sap feeding insects to occupy a unique ecological niche. Carbon 165-166 SH2 domain containing 1A Homo sapiens 125-128 35421667-1 2022 If we can use toxic aromatic compounds as supplementary carbon source, the simultaneous removal of nitrate (NO3-) and aromatic compounds may be achieved at much lower chemical costs. Carbon 56-62 NBL1, DAN family BMP antagonist Homo sapiens 108-111 35634268-2 2022 These problematic concerns are derived from the complex nature of graphene in the family of sp2-carbon nanoallotropes. Carbon 96-102 Sp2 transcription factor Homo sapiens 92-95 35503527-4 2022 Under N2 atmosphere at room temperature, tBu-TPIRs form SpI with a spiro carbon and a novel HABI isomer tBu-1,4"-HABI, whose bonding pattern is different from that of the original unsubstituted HABI (1,2"-HABI). Carbon 73-79 chromogranin A Homo sapiens 56-59 35594589-0 2022 Using sp2 N atom anchoring effect to prepare ultrafine vanadium nitride particles on porous nitrogen-doped carbon as cathode for lithium-sulfur battery. Carbon 107-113 Sp2 transcription factor Homo sapiens 6-9 35585299-2 2022 For this purpose, the porous MIP sensor was prepared using tetraethyl orthosilicate (TEOS) and cetyltrimethylammonium bromide (CTAB) in the presence of beta-cyclodextrin (beta-CD) as a chiral recognizing element on a glassy carbon electrode (GCE). Carbon 224-230 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 171-178 35226788-4 2022 To verify the validity of these observations, the adsorption behavior of lysozyme onto optically transparent carbon electrodes was also investigated under the influence of an applied alternating potential. Carbon 109-115 lysozyme Homo sapiens 73-81 35577799-1 2022 A tetrasubstituted carbon atom connected by three sp3 or sp2-carbons with single nitrogen, i.e., the alpha-tertiary amine (ATA) functional group, is an essential structure of diverse naturally occurring alkaloids and pharmaceuticals. Carbon 19-25 Sp3 transcription factor Homo sapiens 50-53 35577799-1 2022 A tetrasubstituted carbon atom connected by three sp3 or sp2-carbons with single nitrogen, i.e., the alpha-tertiary amine (ATA) functional group, is an essential structure of diverse naturally occurring alkaloids and pharmaceuticals. Carbon 19-25 Sp2 transcription factor Homo sapiens 57-60 35144170-1 2022 In this study, protein-imprinted sensors were electrochemically fabricated on screen-printed carbon electrodes (SPCEs) for the cytokine interleukin-1beta (IL-1beta) detection. Carbon 93-99 interleukin 1 beta Homo sapiens 136-153 35176696-5 2022 Surface ketonic groups were identified as the main reactive sites for non-selective radical production, while crystal edges and structural defects on sp2/sp3 carbon network could smoothly mediate the selective electron transfer from pollutant to oxidant in the non-radical Fenton-like catalysis. Carbon 158-164 Sp2 transcription factor Homo sapiens 150-153 35176696-5 2022 Surface ketonic groups were identified as the main reactive sites for non-selective radical production, while crystal edges and structural defects on sp2/sp3 carbon network could smoothly mediate the selective electron transfer from pollutant to oxidant in the non-radical Fenton-like catalysis. Carbon 158-164 Sp3 transcription factor Homo sapiens 154-157 35594663-4 2022 Subsequent density functional theory (DFT) calculations revealed that the high adsorption capacity for Th(IV) originated from the oxygen-containing groups and their adjacent activated sp2 carbon atoms. Carbon 188-194 Sp2 transcription factor Homo sapiens 184-187 35594589-4 2022 4 nm (VN/M/NC) are successfully grown on the surface of nitrogen-doped three-dimensional carbon using sp2 nitrogen atoms, resulting from melamine pyrolysis in the presence of ammonium metavanadate, as anchor points to lock vanadium atoms in the VN/M/NC material. Carbon 89-95 Sp2 transcription factor Homo sapiens 102-105 35510663-10 2022 Furthermore, poly I:C upregulates TLR3 (SMD = 0.64; CIs (0.56, 0.72); p = 0.00), downregulates nuclear factor-kappaB (NF-kappaB) (SMD = -1.78; CIs (-2.67, -0.88); p = 0.0)), and tumor necrosis factor alpha (TNF-alpha) (SMD = -16.83; CIs (-22.63, -11.02); p = 0.00). Carbon 20-21 nuclear factor kappa B subunit 1 Homo sapiens 95-116 35558826-0 2022 Impact of sp2 carbon material species on Pt nanoparticle-based electrocatalysts produced by one-pot pyrolysis methods with ionic liquids. Carbon 14-20 Sp2 transcription factor Homo sapiens 10-13 35558826-4 2022 All the electrocatalysts, especially Pt/MWCNTs, showed higher durability than the commercial catalyst owing to the combined effect of the IL binder and sp2 carbon materials. Carbon 156-162 Sp2 transcription factor Homo sapiens 152-155 35482971-4 2022 A variety of spectral characterizations and DFT calculation reveal that there is an electron-donating effect of the MOF surface PPh3 toward Pd NPs, which markedly boosts the activation of the carbon-halogen bond in aryl halides. Carbon 192-198 caveolin 1 Homo sapiens 128-132 35507646-3 2022 The end-of-century net carbon sequestration due to bioenergy deployment coupled with carbon capture and storage largely depends on fossil fuel displacement types, ranging from 11.4 to 31.2 PgC over the conterminous United States. Carbon 23-29 progastricsin Homo sapiens 189-192 35507646-3 2022 The end-of-century net carbon sequestration due to bioenergy deployment coupled with carbon capture and storage largely depends on fossil fuel displacement types, ranging from 11.4 to 31.2 PgC over the conterminous United States. Carbon 85-91 progastricsin Homo sapiens 189-192 35507646-4 2022 These net carbon sequestration benefits are inclusive of a 10 PgC carbon release due to land use conversions and a 2.4 PgC loss of additional carbon sink capacity associated with bioenergy-driven deforestation. Carbon 10-16 progastricsin Homo sapiens 62-65 35507646-4 2022 These net carbon sequestration benefits are inclusive of a 10 PgC carbon release due to land use conversions and a 2.4 PgC loss of additional carbon sink capacity associated with bioenergy-driven deforestation. Carbon 142-148 progastricsin Homo sapiens 119-122 35562383-6 2022 As a result, the photochemical approach enables decarboxylative semipinacol rearrangement of beta-hydroxycarboxylic acid derivatives and alkylative semipinacol type rearrangement of allyl alcohols with carbon electrophiles, producing alpha-quaternary or alpha-tertiary carbonyls bearing sp3-rich scaffolds. Carbon 202-208 Sp3 transcription factor Homo sapiens 287-290 35474474-2 2022 In this work, we report CoO nanoparticle decorated N-doped carbon nanotubes as an efficient catalyst for highly selective hydrogenation of NO3- to NH3. Carbon 59-65 NBL1, DAN family BMP antagonist Homo sapiens 139-142 35580459-3 2022 The features of these carbon dots, i.e., their physicochemical and optical properties, their interactions with bovine serum albumin (BSA) as well as their imaging capability were investigated with respect to the CDs prepared with microwave assisted approach (W-CDs). Carbon 22-28 albumin Homo sapiens 118-131 35592850-5 2022 Carbon-based material was used to attach a higher anti-CEA capture aptamer onto the sensor surface through a chemical linker, and then, CEA was quantified by the aptamer. Carbon 0-6 CEA cell adhesion molecule 3 Homo sapiens 55-58 35592850-5 2022 Carbon-based material was used to attach a higher anti-CEA capture aptamer onto the sensor surface through a chemical linker, and then, CEA was quantified by the aptamer. Carbon 0-6 CEA cell adhesion molecule 3 Homo sapiens 136-139 35510663-10 2022 Furthermore, poly I:C upregulates TLR3 (SMD = 0.64; CIs (0.56, 0.72); p = 0.00), downregulates nuclear factor-kappaB (NF-kappaB) (SMD = -1.78; CIs (-2.67, -0.88); p = 0.0)), and tumor necrosis factor alpha (TNF-alpha) (SMD = -16.83; CIs (-22.63, -11.02); p = 0.00). Carbon 20-21 nuclear factor kappa B subunit 1 Homo sapiens 118-127 35510663-10 2022 Furthermore, poly I:C upregulates TLR3 (SMD = 0.64; CIs (0.56, 0.72); p = 0.00), downregulates nuclear factor-kappaB (NF-kappaB) (SMD = -1.78; CIs (-2.67, -0.88); p = 0.0)), and tumor necrosis factor alpha (TNF-alpha) (SMD = -16.83; CIs (-22.63, -11.02); p = 0.00). Carbon 20-21 tumor necrosis factor Homo sapiens 178-205 35510663-10 2022 Furthermore, poly I:C upregulates TLR3 (SMD = 0.64; CIs (0.56, 0.72); p = 0.00), downregulates nuclear factor-kappaB (NF-kappaB) (SMD = -1.78; CIs (-2.67, -0.88); p = 0.0)), and tumor necrosis factor alpha (TNF-alpha) (SMD = -16.83; CIs (-22.63, -11.02); p = 0.00). Carbon 20-21 tumor necrosis factor Homo sapiens 207-216 35442257-1 2022 Two-dimensional (2D) hybrid sp-sp2 carbon systems are an appealing subject for science and technology. Carbon 35-41 Sp2 transcription factor Homo sapiens 31-34 35510618-1 2022 Porous, layered materials containing sp2-hybridized carbon and nitrogen atoms, offer through their tunable properties, a versatile route towards tailormade catalysts for electrochemistry and photochemistry. Carbon 52-58 Sp2 transcription factor Homo sapiens 37-40 35452245-3 2022 The sp3-type defects can be reversibly restored to sp2 carbon centers by the same laser with higher intensity. Carbon 55-61 Sp3 transcription factor Homo sapiens 4-7 35452245-3 2022 The sp3-type defects can be reversibly restored to sp2 carbon centers by the same laser with higher intensity. Carbon 55-61 Sp2 transcription factor Homo sapiens 51-54 35183862-1 2022 In the present work, the performance of aptamer and antibody bioreceptors for the detection of the human epidermal growth factor receptor (HER2) cancer biomarker on a glassy carbon electrode is reported. Carbon 174-180 epidermal growth factor receptor Homo sapiens 105-137 35032519-4 2022 Meanwhile, the sp2-hybridized pi conjugation bond of amorphous carbon can rapidly capture and store photogenerated electrons, inhibiting charge carrier recombination and thus generating more electrons to facilitate the yield of hydroxyl radicals. Carbon 63-69 Sp2 transcription factor Homo sapiens 15-18 35364257-0 2022 Inhibitory Effect of Aptamer-Carbon Dot Nanomaterial-siRNA Complex on the Metastasis of Hepatocellular Carcinoma Cells by Interfering with FMRP. Carbon 29-35 fragile X messenger ribonucleoprotein 1 Homo sapiens 139-143 35183862-1 2022 In the present work, the performance of aptamer and antibody bioreceptors for the detection of the human epidermal growth factor receptor (HER2) cancer biomarker on a glassy carbon electrode is reported. Carbon 174-180 erb-b2 receptor tyrosine kinase 2 Homo sapiens 139-143 35196069-5 2022 Transcriptome-wide analysis revealed a coordinated regulation of metabolic enzymes related to one-carbon metabolism, including three methyltransferase enzymes (KMT2D, SETD1B, and ASH1L), key enzymes for both carnitine synthesis and histone modification. Carbon 98-104 SET domain containing 1B, histone lysine methyltransferase Homo sapiens 167-173 35491241-3 2022 Herein, the design and synthesis of an sp2 -carbon conjugated COF (sp2 -TPE-COF) are reported with surfactant-assisted water dispersion for detecting traces of copper ions based on the photo-induced electron transfer (PET) mechanism. Carbon 44-50 Sp2 transcription factor Homo sapiens 39-42 35299066-2 2022 Besides providing nitrogen substrates and carbon framework for energy homeostasis and transamination, BCAA also function as signaling molecules in the regulation of glucose, lipid, and protein synthesis via protein kinase B and as a mechanistic target of the rapamycin (AKT-mTOR) signaling pathway that is important for muscle accretion. Carbon 42-48 AT-rich interaction domain 4B Homo sapiens 102-106 35413202-1 2022 Compounds rich in sp3-hybridized carbons are desirable in drug discovery. Carbon 33-40 Sp3 transcription factor Homo sapiens 18-21 35602962-4 2022 Similarly, higher carbon fixation potential of AOA, evaluated by the ratios of amoA to accA gene, was also observed below euphotic zone and the ratios increased with increasing water depth. Carbon 18-24 G protein-coupled receptor 3 Homo sapiens 87-91 35420437-0 2022 Absolute Quantification of sp3 Defects in Semiconducting Single-Wall Carbon Nanotubes by Raman Spectroscopy. Carbon 69-75 Sp3 transcription factor Homo sapiens 27-30 35420437-1 2022 The functionalization of semiconducting single-wall carbon nanotubes (SWCNTs) with luminescent sp3 defects creates red-shifted emission features in the near-infrared and boosts their photoluminescence quantum yields (PLQYs). Carbon 52-58 Sp3 transcription factor Homo sapiens 95-98 35060667-1 2022 In this study, a sensitive platform was designed for the electrocatalytical oxidation and recognition of ascorbic acid (AA) based on poly(beta-cyclodextrin) modified glassy carbon electrode (p(beta-CD-GCE). Carbon 173-179 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 193-200 35530351-0 2022 IL1 Pathway in HPV-Negative HNSCC Cells Is an Indicator of Radioresistance After Photon and Carbon Ion Irradiation Without Functional Involvement. Carbon 92-98 interleukin 1 beta Homo sapiens 0-3 35132754-6 2022 Moreover, by integrating carbon dots into CNC films, CPL emission with considerable luminescence dissymmetry factor (g lum ) up to -0.66 was achieved, and it could be used for the photo-alignment of Azo polymers with high chiroptical property. Carbon 25-31 lumican Homo sapiens 119-122 35440564-6 2022 The observation-constrained models show a decrease in the tropical forest carbon sink by the end of the century, particularly across South America (from 2 to 1.4 PgC y-1), and an increase in the sink in North America (from 0.8 to 1.1 PgC y-1). Carbon 74-80 progastricsin Homo sapiens 162-165 35384955-3 2022 The limiting stage is the stage of cyclization involving the intramolecular attack by the amino group of the precyclic intermediate on the carbon atom bound to the hydroxyl group with the simultaneous release of a water molecule according to the SN2 mechanism. Carbon 139-145 solute carrier family 38 member 5 Homo sapiens 246-249 35564347-1 2022 Accurate predictions of CO2 emissions have important practical significance for determining the best measures for reducing CO2 emissions and accomplishing the target of reaching a carbon peak. Carbon 180-186 amyloid beta precursor protein Homo sapiens 178-179 35172039-2 2022 Herein, we demonstrate the synthesis of a Co II diketimide complex (( Tr L)Co(NC 6 F 5 )) 2 and its reversible C-C bond cleavage to yield a monomeric Co nitrenoid complex ( Tr L)Co(NC 6 F 5 ). Carbon 111-112 mitochondrially encoded cytochrome c oxidase II Homo sapiens 42-47 35172039-2 2022 Herein, we demonstrate the synthesis of a Co II diketimide complex (( Tr L)Co(NC 6 F 5 )) 2 and its reversible C-C bond cleavage to yield a monomeric Co nitrenoid complex ( Tr L)Co(NC 6 F 5 ). Carbon 113-114 mitochondrially encoded cytochrome c oxidase II Homo sapiens 42-47 35443173-4 2022 IFNbeta also increased the flux of glutamine-derived carbon into the tricarboxylic acid cycle to boost succinate levels. Carbon 53-59 IFN1@ Homo sapiens 0-7 35440564-6 2022 The observation-constrained models show a decrease in the tropical forest carbon sink by the end of the century, particularly across South America (from 2 to 1.4 PgC y-1), and an increase in the sink in North America (from 0.8 to 1.1 PgC y-1). Carbon 74-80 progastricsin Homo sapiens 234-237 35481096-1 2022 A highly efficient heterogeneous catalyst was synthesized by delicate engineering of NH2-functionalized and N-doped hollow mesoporous carbon spheres (NH2-N-HMCS), which was used for supporting AuPd alloy nanoparticles with ultrafine size and good dispersion (denoted as AuPd/NH2-N-HMCS). Carbon 134-140 MKKS centrosomal shuttling protein Homo sapiens 156-160 35481096-1 2022 A highly efficient heterogeneous catalyst was synthesized by delicate engineering of NH2-functionalized and N-doped hollow mesoporous carbon spheres (NH2-N-HMCS), which was used for supporting AuPd alloy nanoparticles with ultrafine size and good dispersion (denoted as AuPd/NH2-N-HMCS). Carbon 134-140 MKKS centrosomal shuttling protein Homo sapiens 281-285 35435232-2 2022 Here we show that the transcription of SHAGGY-like kinase 11/12 (SK11/12), two members of the GSK3 gene family, is promoted by the splicing factor SmD1b, which is essential for distributing carbon sources into storage and protective components in Arabidopsis seeds. Carbon 190-196 shaggy-related kinase 11 Arabidopsis thaliana 39-72 35435232-5 2022 These effects imposed by SmD1b determine the transcription of SK11/12 to confer a key switch of carbon flow among metabolic pathways in zygotic and maternal tissues in seeds. Carbon 96-102 shaggy-related kinase 11 Arabidopsis thaliana 62-69 35364808-1 2022 An enantiopure ligand with four bidentate metal-binding sites and four (S)-carbon stereocenters self-assembles with octahedral ZnII or CoII to produce O-symmetric M8L6 coordination cages. Carbon 75-81 mitochondrially encoded cytochrome c oxidase II Homo sapiens 135-139 34998196-6 2022 X-ray photoelectron spectroscopy (XPS), solid-state nuclear magnetic resonance (ssNMR) and X-ray absorption near-edge structure (XANES) spectroscopy reveal that the carbon and oxygen dopants replace the sp2 nitrogen and bridging N atom, respectively. Carbon 165-171 Sp2 transcription factor Homo sapiens 203-206 35385313-4 2022 In the absence of FGF21, a large part of the metabolic adaptation to mitochondrial dysfunction (one-carbon metabolism, transsulfuration, and serine and proline biosynthesis) is strongly blunted, independent of the primary mitoISR activator ATF4. Carbon 100-106 fibroblast growth factor 21 Homo sapiens 18-23 35299236-2 2022 Here, a bimetallic FeCo2O4 spinel nanowire array grown on carbon cloth is proposed as an efficient electrocatalyst for the conversion of NO3- to NH3 with a high faradaic efficiency of up to 95.9% and a large NH3 yield of 4988 mug h-1 cm-2. Carbon 58-64 NBL1, DAN family BMP antagonist Homo sapiens 137-140 35157327-2 2022 In particular, vinylene-linked 2D CPs with fully in-plane sp2-carbon-conjugated structures, high thermal and chemical stability, have become the focus of attention. Carbon 62-68 Sp2 transcription factor Homo sapiens 58-61 35408032-5 2022 For the analysis of incorporated carbon species, X-ray photoelectron and Auger spectroscopies were applied, indicating the presence of carbon in both the sp2 and the sp3 states. Carbon 33-39 Sp2 transcription factor Homo sapiens 154-157 35311249-5 2022 In detection process of the sandwich-type electrochemical immunosensor, glassy carbon electrode (GCE) was modified with 2D COFTab-Dva first then connected with Ab1 by the thiol-ene "click" reaction, next quantitative CEA was captured, followed by specificially capturing signal probe of Ab2/AuNPs/COFTFPB-Thi where AuNPs acted as nanocarriers of Ab2 and COFTFPB-Thi served as the signal producers. Carbon 79-85 CEA cell adhesion molecule 3 Homo sapiens 217-220 35408032-5 2022 For the analysis of incorporated carbon species, X-ray photoelectron and Auger spectroscopies were applied, indicating the presence of carbon in both the sp2 and the sp3 states. Carbon 33-39 Sp3 transcription factor Homo sapiens 166-169 35408032-5 2022 For the analysis of incorporated carbon species, X-ray photoelectron and Auger spectroscopies were applied, indicating the presence of carbon in both the sp2 and the sp3 states. Carbon 135-141 Sp2 transcription factor Homo sapiens 154-157 35408032-5 2022 For the analysis of incorporated carbon species, X-ray photoelectron and Auger spectroscopies were applied, indicating the presence of carbon in both the sp2 and the sp3 states. Carbon 135-141 Sp3 transcription factor Homo sapiens 166-169 35353621-5 2022 Pyruvate carboxylase provides sufficient anaplerotic carbons to support citrate secretion. Carbon 53-60 pyruvate carboxylase Homo sapiens 0-20 35382861-9 2022 A fraction of PPFIA4 localizes to mitochondria and interacts with MTHFD2, a key enzyme for one-carbon metabolism. Carbon 95-101 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase Mus musculus 66-72 35174979-2 2022 Diamanes and diamanoids are the new nanoallotropes of sp3 hybridized carbon which can be fabricated by proper functionalization, substitution, and via Birch reduction under controlled pressure using graphitic system as a precursor. Carbon 69-75 Sp3 transcription factor Homo sapiens 54-57 35373919-4 2022 With a polyvinyl pyrrolidone (PVP)-assisted approach, 2D Cu-FDC nano-lamellae of micrometer lateral dimensions and nanometer thickness can be obtained, which can be used as a precursor to fabricate 2D oxygen-rich carbon nanosheets embedding with Cu nanoparticles (denoted CFP-300) after a thermal treatment at 300 o C under N 2 atmosphere. Carbon 213-219 complement factor properdin Homo sapiens 272-275 35407318-0 2022 In Situ Synthesis of Carbon Nanotube-Steel Slag Composite for Pb(II) and Cu(II) Removal from Aqueous Solution. Carbon 21-27 submaxillary gland androgen regulated protein 3B Homo sapiens 62-68 35178779-1 2022 Solution-processed, large-area, and flexible electronics largely relies on the excellent electronic properties of sp2 -hybridized carbon molecules, either in the form of pi-conjugated small molecules and polymers or graphene and carbon nanotubes. Carbon 130-136 Sp2 transcription factor Homo sapiens 114-117 35178779-1 2022 Solution-processed, large-area, and flexible electronics largely relies on the excellent electronic properties of sp2 -hybridized carbon molecules, either in the form of pi-conjugated small molecules and polymers or graphene and carbon nanotubes. Carbon 229-235 Sp2 transcription factor Homo sapiens 114-117 35224845-2 2022 In this work, an efficient HER catalyst, Ru@COF-1, is prepared by complexation of triazine-cored sp2 carbon-conjugated covalent organic frameworks (COFs) with ruthenium ion. Carbon 101-107 Sp2 transcription factor Homo sapiens 97-100 35174545-9 2022 Taken together, these results demonstrate that melatonin promotes plant tolerance against carbon starvation by upregulating the expression of miR171b, which can directly inhibit GWD expression in tomato leaves. Carbon 90-96 MIR171b Solanum lycopersicum 142-149 35174545-9 2022 Taken together, these results demonstrate that melatonin promotes plant tolerance against carbon starvation by upregulating the expression of miR171b, which can directly inhibit GWD expression in tomato leaves. Carbon 90-96 glucan water dikinase Solanum lycopersicum 178-181 35193747-1 2022 Qua-Quine Starch (QQS), an orphan gene exclusively found in Arabidopsis thaliana, interacts with Nuclear Factor Y subunit C4 (NF-YC4) and regulates carbon and nitrogen allocation in different plant species. Carbon 148-154 qua-quine starch Arabidopsis thaliana 18-21 35193747-8 2022 Further analysis revealed that QQS expression and overexpression of NtNF-YC4 strongly repressed expression of genes such as sugar transporter SWEET10 and Flowering Locus T (FT), suggesting involvement of SWEET10 and FT in the QQS and NF-YC4 mediated carbon and nitrogen allocation in tobacco. Carbon 250-256 qua-quine starch Arabidopsis thaliana 226-229 35193747-8 2022 Further analysis revealed that QQS expression and overexpression of NtNF-YC4 strongly repressed expression of genes such as sugar transporter SWEET10 and Flowering Locus T (FT), suggesting involvement of SWEET10 and FT in the QQS and NF-YC4 mediated carbon and nitrogen allocation in tobacco. Carbon 250-256 nuclear factor Y, subunit C4 Arabidopsis thaliana 234-240 35119186-7 2022 The Co(III)-rich environment endows the in situ formed CoFe oxyhydroxide with high catalytic activity for OER on a simple flat glassy carbon electrode, outperforming those not treated by the sacrificial W procedure. Carbon 134-140 mitochondrially encoded cytochrome c oxidase III Homo sapiens 4-11 35129312-2 2022 Here, a facile pyrolysis method to obtain phase-pure CrP nanoparticles supported on N, P dual-doped carbon (CrP/NPC) is reported to be tuned toward industrial HER. Carbon 100-106 C-reactive protein Homo sapiens 53-56 35129312-2 2022 Here, a facile pyrolysis method to obtain phase-pure CrP nanoparticles supported on N, P dual-doped carbon (CrP/NPC) is reported to be tuned toward industrial HER. Carbon 100-106 C-reactive protein Homo sapiens 108-111 35101826-0 2022 Synthesis of carbon quantum dots for application of alleviating amyloid-beta mediated neurotoxicity. Carbon 13-19 amyloid beta precursor protein Homo sapiens 64-76 35497383-1 2022 We demonstrate the density and shape of platinum nanoparticles (PtNP) on carbon-fiber microelectrodes with fast-scan cyclic voltammetry (FSCV) directly impacts detection of adenosine. Carbon 73-79 Fas activated serine/threonine kinase Homo sapiens 107-111 35174545-8 2022 Crucially, GWD gene was identified as a target of miR171b, and the overexpression of miR171b ameliorated the carbon starvation-induced degradation of chlorophyll and starch, and inhibited the expression of GWD gene. Carbon 109-115 glucan water dikinase Solanum lycopersicum 11-14 35174545-8 2022 Crucially, GWD gene was identified as a target of miR171b, and the overexpression of miR171b ameliorated the carbon starvation-induced degradation of chlorophyll and starch, and inhibited the expression of GWD gene. Carbon 109-115 MIR171b Solanum lycopersicum 85-92 35486466-3 2022 Carbon felt and granular graphite were used as anodes in MEC-1 and MEC-2, respectively. Carbon 0-6 ATR serine/threonine kinase Homo sapiens 57-62 35302380-1 2022 The degree of laser-induced graphitization from a sp3-bonded to a sp2-bonded carbon fraction in a single crystal chemical vapor deposited (CVD) diamond under varying fluence of an ultrashort pulsed laser (30 fs, 800 nm, 1 kHz) irradiation has been studied. Carbon 77-83 Sp2 transcription factor Homo sapiens 66-69 35433633-0 2022 Pd@Py2PZ@MSN as a Novel and Efficient Catalyst for C-C Bond Formation Reactions. Carbon 51-52 moesin Homo sapiens 9-12 35433633-0 2022 Pd@Py2PZ@MSN as a Novel and Efficient Catalyst for C-C Bond Formation Reactions. Carbon 53-54 moesin Homo sapiens 9-12 35302380-2 2022 The tetrahedral CVD sp3 phase is found to transition to primarily an sp2 aromatic crystalline graphitic fraction below the critical fluence of 3.9 J/cm2, above which predominantly an amorphous carbon is formed. Carbon 193-199 Sp3 transcription factor Homo sapiens 20-23 35302380-2 2022 The tetrahedral CVD sp3 phase is found to transition to primarily an sp2 aromatic crystalline graphitic fraction below the critical fluence of 3.9 J/cm2, above which predominantly an amorphous carbon is formed. Carbon 193-199 Sp2 transcription factor Homo sapiens 69-72 35378390-0 2022 Carbon pathways during transitory starch degradation in Arabidopsis differentially affect the starch granule number and morphology in the dpe2/phs1 mutant background. Carbon 0-6 disproportionating enzyme 2 Arabidopsis thaliana 138-142 35408313-0 2022 Impedance Technique-Based Label-Free Electrochemical Aptasensor for Thrombin Using Single-Walled Carbon Nanotubes-Casted Screen-Printed Carbon Electrode. Carbon 97-103 coagulation factor II, thrombin Homo sapiens 68-76 35408313-0 2022 Impedance Technique-Based Label-Free Electrochemical Aptasensor for Thrombin Using Single-Walled Carbon Nanotubes-Casted Screen-Printed Carbon Electrode. Carbon 136-142 coagulation factor II, thrombin Homo sapiens 68-76 35408313-1 2022 An impedance technique-based aptasensor for the detection of thrombin was developed using a single-walled carbon nanotube (SWCNT)-modified screen-printed carbon electrode (SPCE). Carbon 106-112 coagulation factor II, thrombin Homo sapiens 61-69 35408313-1 2022 An impedance technique-based aptasensor for the detection of thrombin was developed using a single-walled carbon nanotube (SWCNT)-modified screen-printed carbon electrode (SPCE). Carbon 154-160 coagulation factor II, thrombin Homo sapiens 61-69 35424922-1 2022 We report herein a highly efficient strategy for construction of a bridged oxa-(3.2.1)octane-embedded 5-7-6 tricyclic carbon skeleton through (3 + 2) IMCC (intramolecular (3 + 2) cross-cycloaddition), and the substituents and/or stereochemistries on C-4, C-6, C-7 and C-10 fully match those in the rhamnofolane, tigliane and daphnane diterpenoids. Carbon 118-124 homeobox C10 Homo sapiens 268-272 35355680-0 2022 Carbon ion radiotherapy triggers immunogenic cell death and sensitizes melanoma to anti-PD-1 therapy in mice. Carbon 0-6 programmed cell death 1 Mus musculus 88-92 35424922-1 2022 We report herein a highly efficient strategy for construction of a bridged oxa-(3.2.1)octane-embedded 5-7-6 tricyclic carbon skeleton through (3 + 2) IMCC (intramolecular (3 + 2) cross-cycloaddition), and the substituents and/or stereochemistries on C-4, C-6, C-7 and C-10 fully match those in the rhamnofolane, tigliane and daphnane diterpenoids. Carbon 250-251 homeobox C10 Homo sapiens 268-272 35424922-1 2022 We report herein a highly efficient strategy for construction of a bridged oxa-(3.2.1)octane-embedded 5-7-6 tricyclic carbon skeleton through (3 + 2) IMCC (intramolecular (3 + 2) cross-cycloaddition), and the substituents and/or stereochemistries on C-4, C-6, C-7 and C-10 fully match those in the rhamnofolane, tigliane and daphnane diterpenoids. Carbon 255-256 homeobox C10 Homo sapiens 268-272 35424922-1 2022 We report herein a highly efficient strategy for construction of a bridged oxa-(3.2.1)octane-embedded 5-7-6 tricyclic carbon skeleton through (3 + 2) IMCC (intramolecular (3 + 2) cross-cycloaddition), and the substituents and/or stereochemistries on C-4, C-6, C-7 and C-10 fully match those in the rhamnofolane, tigliane and daphnane diterpenoids. Carbon 260-261 homeobox C10 Homo sapiens 268-272 35190130-2 2022 We found that the sp3-hybridized carbon and nitrogen atoms were more susceptible to be etched than the sp2-hybridized atoms, resulting in the decrease of amorphous and the formation of more graphene edges. Carbon 33-39 Sp3 transcription factor Homo sapiens 18-21 35245425-0 2022 Direct SN2 or SN2X Manifold Mechanistic Study of Ion-Pair-Catalyzed Carbon(sp3)-Carbon(sp3) Bond Formation. Carbon 80-86 solute carrier family 38 member 5 Homo sapiens 7-10 35245425-0 2022 Direct SN2 or SN2X Manifold Mechanistic Study of Ion-Pair-Catalyzed Carbon(sp3)-Carbon(sp3) Bond Formation. Carbon 80-86 Sp3 transcription factor Homo sapiens 75-78 35245425-0 2022 Direct SN2 or SN2X Manifold Mechanistic Study of Ion-Pair-Catalyzed Carbon(sp3)-Carbon(sp3) Bond Formation. Carbon 80-86 Sp3 transcription factor Homo sapiens 87-90 35245425-1 2022 Density functional theory (DFT) is used in this work to predict the mechanism for constructing congested quaternary-quaternary carbon(sp3)-carbon(sp3) bonds in a pentanidium-catalyzed substitution reaction. Carbon 127-133 Sp3 transcription factor Homo sapiens 134-137 35245425-1 2022 Density functional theory (DFT) is used in this work to predict the mechanism for constructing congested quaternary-quaternary carbon(sp3)-carbon(sp3) bonds in a pentanidium-catalyzed substitution reaction. Carbon 127-133 Sp3 transcription factor Homo sapiens 146-149 35245425-1 2022 Density functional theory (DFT) is used in this work to predict the mechanism for constructing congested quaternary-quaternary carbon(sp3)-carbon(sp3) bonds in a pentanidium-catalyzed substitution reaction. Carbon 139-145 Sp3 transcription factor Homo sapiens 134-137 35245425-1 2022 Density functional theory (DFT) is used in this work to predict the mechanism for constructing congested quaternary-quaternary carbon(sp3)-carbon(sp3) bonds in a pentanidium-catalyzed substitution reaction. Carbon 139-145 Sp3 transcription factor Homo sapiens 146-149 35230820-6 2022 The PDP PNPs were modified onto the surface of a glassy carbon electrode (GCE) to capture the first antibody (Ab1) and further capture antigen and secondary antibody complexes (TDBA-beta-CD-Pt@Ab2). Carbon 56-62 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 182-189 35409465-7 2022 Thereafter, the association between methylenetetrahydrofolate reductase (Mthfr a key enzyme in one-carbon metabolism and DNA-methylation-induced regulation of gene transcription) and lipogenic genes was evaluated using Pearson"s correlation coefficient. Carbon 99-105 methylenetetrahydrofolate reductase Mus musculus 36-71 35409465-7 2022 Thereafter, the association between methylenetetrahydrofolate reductase (Mthfr a key enzyme in one-carbon metabolism and DNA-methylation-induced regulation of gene transcription) and lipogenic genes was evaluated using Pearson"s correlation coefficient. Carbon 99-105 methylenetetrahydrofolate reductase Mus musculus 73-78 35298317-0 2022 Effect of NLRP3 repression on NLRP3 inflammasome activation in human corneal epithelial cells with black carbon exposure. Carbon 105-111 NLR family pyrin domain containing 3 Homo sapiens 10-15 35323442-6 2022 Herein, we proposed two strategies for the detection of three mTBI-relevant biomarkers (GFAP, h-FABP, and S100beta), in standard solutions and in human serum samples by using an electrochemiluminescence (ECL) immunoassay on (i) a commercial ECL platform in 96-well plate format, and (ii) a "POC-friendly" platform with disposable screen-printed carbon electrodes (SPCE) and a portable ECL reader. Carbon 345-351 fatty acid binding protein 3 Homo sapiens 94-100 35601978-1 2022 We developed an electrochemical biosensing platform using gold-clusters, cysteamine, the spike protein of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antigen and bovine serum albumin on a glassy carbon electrode able to determine the SARS-CoV-2 spike antibody. Carbon 216-222 albumin Homo sapiens 190-203 35323442-6 2022 Herein, we proposed two strategies for the detection of three mTBI-relevant biomarkers (GFAP, h-FABP, and S100beta), in standard solutions and in human serum samples by using an electrochemiluminescence (ECL) immunoassay on (i) a commercial ECL platform in 96-well plate format, and (ii) a "POC-friendly" platform with disposable screen-printed carbon electrodes (SPCE) and a portable ECL reader. Carbon 345-351 S100 calcium binding protein A1 Homo sapiens 106-114 35212216-0 2022 Low-Temperature Synthesis of Lithium Lanthanum Titanate/Carbon Nanowires for Fast-Charging Li-Ion Batteries. Carbon 56-62 Fas activated serine/threonine kinase Homo sapiens 77-81 35191443-5 2022 A detailed analysis of electronic properties reveals that the metallicity mainly comes from the pz-orbital of sp2-hybridized carbon atoms. Carbon 125-131 Sp2 transcription factor Homo sapiens 110-113 35226486-1 2022 Mesoporous Pt-Pd bimetallic core-shell nanospheres (mPd@Pt NSs) with palladium-rich cores and platinum-rich shells were synthesized via a simple, two-step, wet chemical strategy mediated by nitrogen-doped carbon dots. Carbon 205-211 mevalonate (diphospho) decarboxylase Mus musculus 52-55 35212216-7 2022 The low-temperature-synthesized pure LLTO/carbon composite nanowires (P-LLTO/C NWs) exhibit improved lithium storage performances than the traditionally prepared LLTO due to the fast electronic conduction of carbon and the stable carbon surface. Carbon 208-214 Fas activated serine/threonine kinase Homo sapiens 178-182 35212216-7 2022 The low-temperature-synthesized pure LLTO/carbon composite nanowires (P-LLTO/C NWs) exhibit improved lithium storage performances than the traditionally prepared LLTO due to the fast electronic conduction of carbon and the stable carbon surface. Carbon 42-48 Fas activated serine/threonine kinase Homo sapiens 178-182 35192343-3 2022 These compounds are also prepared from cyclic six-membered (tap)PdCl2 (5; tap = triazapentadiene) or formamidinium salts (6a-6c) with Pd(OAc)2/NaOAc in acetonitrile, whereas the direct reaction of 2 with acetonitrile or acrylonitrile resulted in palladium black or an acyclic C-N-coupled product (3). Carbon 276-277 SEC14 like lipid binding 2 Homo sapiens 60-63 35261309-11 2022 Conclusion: Prior supplementation of the combination of vitamins C and E attenuates OS (lipid peroxidation), the inflammatory response (interleukin-6), cortisol levels, and muscle damage (creatine kinase) following a session of exercise. Carbon 65-66 interleukin 6 Homo sapiens 136-149 35168734-2 2022 Herein, we report on the high specificity and electrocatalytic activity of CNT/ABTS(CV) nanozyme, derived from the electrochemical functionalization of the carbon nanotube/2,2"-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) nanocomposite CNT/ABTS), towards electrochemical oxidation of human serum albumin (HSA) in urine. Carbon 156-162 albumin Homo sapiens 296-309 35192343-3 2022 These compounds are also prepared from cyclic six-membered (tap)PdCl2 (5; tap = triazapentadiene) or formamidinium salts (6a-6c) with Pd(OAc)2/NaOAc in acetonitrile, whereas the direct reaction of 2 with acetonitrile or acrylonitrile resulted in palladium black or an acyclic C-N-coupled product (3). Carbon 276-277 SEC14 like lipid binding 2 Homo sapiens 74-77 35020395-2 2022 Herein, we introduce a per-/polyfluoroaryl moiety, which serves as a redox-active scaffold, into sp3-hybridized thiols to activate the C-S bond. Carbon 135-136 Sp3 transcription factor Homo sapiens 97-100 35045708-0 2022 Visible-Light-Induced Selective C-C Bond Cleavage Reactions of Dimeric beta-O-4 and beta-1 Lignin Model Substrates Utilizing Amine-Functionalized Fullerene. Carbon 32-33 BCL2 related protein A1 Homo sapiens 84-90 35269813-8 2022 Our work reveals that the PLC conjugate with the 12-carbon linker length yields the optimal prodrug activation by PLA2 in comparison to shorter linker length (6-carbons). Carbon 52-58 phospholipase A2 group IB Homo sapiens 114-118 35093525-5 2022 Protein (PN)/polysaccharose (PS) values and ETSA decreased with the decrease of C/N ratios. Carbon 80-81 U6 snRNA biogenesis phosphodiesterase 1 Homo sapiens 9-11 35100570-1 2022 The search for sp3-hybridized carbon allotropes other than diamond has attracted extensive interest because of their fascinating properties. Carbon 30-36 Sp3 transcription factor Homo sapiens 15-18 35100570-2 2022 In this paper, an orthorhombic carbon phase in sp3 bonding, named pentaheptite diamond, by combining the particle swarm optimization method with first-principles calculations has been predicted. Carbon 31-37 Sp3 transcription factor Homo sapiens 47-50 35110739-4 2022 Here we present how to use diazonium salt chemistry to introduce sp3 quantum defects in the SWCNT carbon lattice to serve as handles for conjugation while preserving near-infrared fluorescence. Carbon 98-104 Sp3 transcription factor Homo sapiens 65-68 35086163-7 2022 To further increase propionate production, carbon flux was pulled into the propionate pathway by weakened expression of pyruvate kinase (PYK1), together with overexpression of phosphoenolpyruvate carboxylase (ppc). Carbon 43-49 pyruvate kinase CDC19 Saccharomyces cerevisiae S288C 137-141 35106766-7 2022 The results of molecular docking and dynamics simulation demonstrated that the subtle structural differences of 20(R, S)-Rh1 at the 20-carbon atom may be responsible for their different binding capacities and binding stabilities with human serum albumin. Carbon 135-141 albumin Homo sapiens 240-253 35103291-7 2022 Specific knockdown of ZAPL and ZAPS in RT7 cells decreased IFN-beta and C-X-C motif chemokine ligand 10 (CXCL10) expression induced by transfected Poly(I:C) and Poly(dA:dT). Carbon 154-155 outer dense fiber of sperm tails 1 Homo sapiens 39-42 35103291-7 2022 Specific knockdown of ZAPL and ZAPS in RT7 cells decreased IFN-beta and C-X-C motif chemokine ligand 10 (CXCL10) expression induced by transfected Poly(I:C) and Poly(dA:dT). Carbon 154-155 IFN1@ Homo sapiens 59-67 35121066-18 2022 Inhibition of CYP2D6, CYP2C19 and CYP3A4 increased with increasing chain-lengths between six and nine carbons. Carbon 102-109 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 14-20 35121066-18 2022 Inhibition of CYP2D6, CYP2C19 and CYP3A4 increased with increasing chain-lengths between six and nine carbons. Carbon 102-109 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 34-40 35218132-1 2022 3D hierarchical carbon nanocages (hCNC) are becoming new platforms for advanced energy storage and conversion due to their unique structural characteristics, especially the combination of multiscale pore structure with high conductivity of sp2 carbon frameworks, which can promote the mass/charge synergetic transfer in various electrochemical processes. Carbon 16-22 Sp2 transcription factor Homo sapiens 240-243 35270394-7 2022 SPSS analysis showed that dissolved organic carbon (DOC) in surface water was significantly correlated with the concentration of DBP, DEHP, and the 6PAEs, while organic matter (OM) was significantly correlated with the concentration of the 6PAEs in sediments. Carbon 44-50 D-box binding PAR bZIP transcription factor Homo sapiens 129-132 35218132-1 2022 3D hierarchical carbon nanocages (hCNC) are becoming new platforms for advanced energy storage and conversion due to their unique structural characteristics, especially the combination of multiscale pore structure with high conductivity of sp2 carbon frameworks, which can promote the mass/charge synergetic transfer in various electrochemical processes. Carbon 244-250 Sp2 transcription factor Homo sapiens 240-243 35214200-0 2022 Carboxyl-Functionalized Carbon Nanotubes Loaded with Cisplatin Promote the Inhibition of PI3K/Akt Pathway and Suppress the Migration of Breast Cancer Cells. Carbon 24-30 AKT serine/threonine kinase 1 Homo sapiens 94-97 35040631-0 2022 Reconfiguring Organic Color Centers on the sp2 Carbon Lattice of Single-Walled Carbon Nanotubes. Carbon 47-53 Sp2 transcription factor Homo sapiens 43-46 35040631-0 2022 Reconfiguring Organic Color Centers on the sp2 Carbon Lattice of Single-Walled Carbon Nanotubes. Carbon 79-85 Sp2 transcription factor Homo sapiens 43-46 35147148-2 2022 The BPN structure consists of four-, six-, and eight-membered rings of sp2-hybridized carbon atoms. Carbon 86-92 Sp2 transcription factor Homo sapiens 71-74 35107471-8 2022 The integrity of the cell wall and the cell membrane were damaged for Pseudomonas fragi, and the extracellular alkaline phosphatase (AKP) and ATP activity also increased after exposure to the onion carbon dots, thus leading to a decrease in the cell viability and alteration of the cellular morphology for Pseudomonas fragi. Carbon 198-204 AV641_RS14600 Pseudomonas fragi 111-131 35214200-4 2022 Hence, the main purpose of this study was to design a nanoconjugate based on single-walled carbon nanotubes functionalized with carboxyl groups (SWCNT-COOH) and cisplatin (CDDP) and to explore the potential of inhibiting the PI3K/Akt signaling pathway. Carbon 91-97 AKT serine/threonine kinase 1 Homo sapiens 230-233 35494099-2 2022 Supported by D 2-symmetric chiral amidoporphyrin ligand, Co(II)-based metalloradical system can efficiently activate unsymmetrical methyl phenyl diazomalonate (MPDM) with effective differentiation of the two ester groups for asymmetric cyclopropanation, enabling stereoselective construction of 1,1-cyclopropanediesters bearing two contiguous chiral centers, including all-carbon quaternary stereogenic center. Carbon 373-379 mitochondrially encoded cytochrome c oxidase II Homo sapiens 57-63 35203701-5 2022 The LL-37/poly I:C-induced upregulation of TLR3 mRNA expression was prevented by the endosomal acidification inhibitor chloroquine, indicating involvement of downstream TLR3 signaling. Carbon 17-18 cathelicidin antimicrobial peptide Homo sapiens 4-9 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 42-43 cathelicidin antimicrobial peptide Homo sapiens 17-22 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 42-43 cathelicidin antimicrobial peptide Homo sapiens 147-152 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 42-43 nuclear factor kappa B subunit 1 Homo sapiens 262-271 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 136-137 cathelicidin antimicrobial peptide Homo sapiens 17-22 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 160-161 cathelicidin antimicrobial peptide Homo sapiens 17-22 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 160-161 cathelicidin antimicrobial peptide Homo sapiens 147-152 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 160-161 nuclear factor kappa B subunit 1 Homo sapiens 262-271 35113524-0 2022 New Insights into the Effects of Zr Substitution and Carbon Additive on Li3-xEr1-xZrxCl6 Halide Solid Electrolytes. Carbon 53-59 cytochrome P450 family 4 subfamily F member 22 Homo sapiens 72-75 35107452-1 2022 Functionalized carbon nanotubes (CNTs) can inhibit the self-assembly of amyloid-beta (Abeta) peptides. Carbon 15-21 amyloid beta precursor protein Homo sapiens 72-84 35107452-1 2022 Functionalized carbon nanotubes (CNTs) can inhibit the self-assembly of amyloid-beta (Abeta) peptides. Carbon 15-21 amyloid beta precursor protein Homo sapiens 86-91 35113103-4 2022 Here, using all-atom solvent explicit molecular dynamics simulations, we further investigate the molecular origin of the variation of this ESP for two prototypical cases of proteins or nucleic acids attached to a carbon nanotube bioFET: the function of the lysozyme protein and the hybridization of a 10-nt DNA sequence, as previously done experimentally. Carbon 213-219 lysozyme Homo sapiens 257-265 35273682-0 2022 A novel signal enhancement strategy for the detection of DNA oxidative damage biomarker 8-OHdG based on the synergy between beta-CD-CuNCs and multi-walled carbon nanotubes. Carbon 155-161 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 124-131 35107979-3 2022 Here, we used fast-scan cyclic voltammetry at carbon-fiber microelectrodes and flow injection analysis to optimize a waveform for the measurement of oxytocin. Carbon 46-52 oxytocin Danio rerio 149-157 35273682-1 2022 OBJECTIVE: To propose a novel signal enhancement strategy based on the synergy between beta-CD-CuNCs and multi-walled carbon nanotubes (MWCNTs) for the detection of DNA oxidative damage biomarker 8-Hydroxy-2"-deoxyguanosine (8-OHdG). Carbon 118-124 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 87-94 35131931-1 2022 A network of tetrahedral vertices can fill three-dimensional (3D) spaces in a beautiful and isotropic manner, which is found as diamonds with sp3-hybridized carbon atoms. Carbon 157-163 Sp3 transcription factor Homo sapiens 142-145 35131931-2 2022 Although a network of trigonal vertices (i.e., another form of carbon atoms with sp2-hybridization) naturally results in a lower-dimensional two-dimensional network of graphenes, an isotropic 3D arrangement of trigonal vertices has been of theoretical and mathematical interest, which has materialized as a proposal of a "diamond twin." Carbon 63-69 Sp2 transcription factor Homo sapiens 81-84 35214926-3 2022 Not existing individually, these molecules are met in practice as basic structure units of complex multilevel structure of all sp2 amorphous carbons. Carbon 141-148 Sp2 transcription factor Homo sapiens 127-130 35224328-8 2022 The results show that the surface functionalization reduces the GERS effect because it increases the ratio between the sp3 carbon and sp2 carbon. Carbon 123-129 Sp3 transcription factor Homo sapiens 119-122 35224328-8 2022 The results show that the surface functionalization reduces the GERS effect because it increases the ratio between the sp3 carbon and sp2 carbon. Carbon 138-144 Sp2 transcription factor Homo sapiens 134-137 35224360-1 2022 In this paper, three kinds of carbon fiber papers (CFPs), including pure CFP, poly(tetrafluoroethylene) (PTFE)-treated CFP (PTFE-CFP), and microporous layer (MPL)-coated CFP (MPL-CFP), were used to investigate the effects of the surface structure on the water transport behavior in CFPs. Carbon 30-36 complement factor properdin Homo sapiens 119-122 35138533-5 2022 In this study, carbon-modified TNT (TNT/C) and TNT/C further treated with acid (TNT/HC) were synthesized by hydrothermal synthesis. Carbon 15-21 troponin T2, cardiac type Homo sapiens 36-41 35207817-5 2022 The formation of the TiC phase was attributed to two factors: Firstly, A13Ti as an intermediate product reacted with carbon and formed TiC with increasing temperature. Carbon 117-123 pleckstrin and Sec7 domain containing 4 Homo sapiens 21-24 35207817-5 2022 The formation of the TiC phase was attributed to two factors: Firstly, A13Ti as an intermediate product reacted with carbon and formed TiC with increasing temperature. Carbon 117-123 pleckstrin and Sec7 domain containing 4 Homo sapiens 135-138 35211495-3 2021 Interactions are particularly relevant with the FADS1 and FADS2 genes, which encode key fatty acid desaturases in the pathway that converts LA and ALA to their long chain (>=20 carbons), highly unsaturated fatty acid (HUFA) counterparts. Carbon 177-184 fatty acid desaturase 2 Homo sapiens 58-63 35425434-2 2022 In this study, an attempt has been made to study the interaction involving phosphatidylcholine vesicles (PHOS VES, as model cell membrane) and four different carbon quantum dots bearing different functional groups (-COOH, -NH2, -OH, and protein bovine serum albumin coated) using various tools such as PL behavior, surface charge on vesicles, QCM, ITC, TEM, LSV, and FTIR. Carbon 158-164 albumin Homo sapiens 252-265 35042337-3 2022 Herein, for the first time, we propose a cobalt-catalyzed carbonization strategy to fabricate porous carbon nanofibers that incorporate disordered defects in graphitic domain layers (PCNFs-DG) for fast and durable K+ storage. Carbon 101-107 Fas activated serine/threonine kinase Homo sapiens 197-201 35042337-5 2022 This idea of architecting defected-ordered graphitic carbon engineering guarantees fast reaction kinetics as well as structural stability with negligible interlayer expansion/contraction owing to the uncompromised electronic conductivity, expanded interlayer spacing, and regulated K+ storage mechanism. Carbon 53-59 Fas activated serine/threonine kinase Homo sapiens 83-87 35109908-8 2022 LINC00461 was inversely correlated with the survival of mice-bearing GBM and it was stabilized by the interaction between HDAC6 and RNA-binding proteins (RBPs) such as carbon catabolite repression-negative on TATA-less (CCR4-NOT) core exoribonuclease subunit 6 and fused in sarcoma. Carbon 168-174 histone deacetylase 6 Mus musculus 122-127 35163186-6 2022 The QDs-beta-CD(C-2028)-FA were characterized using DLS (dynamic light scattering), ZP (zeta potential), quartz crystal microbalance with dissipation (QCM-D), and UV-vis spectroscopy. Carbon 16-17 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 8-15 35163453-5 2022 For example, the PrimeEpiHit hypothesis in urothelial carcinoma, which, similarly to malignant melanoma, can also be triggered by a single exogenous noxa, states that one of the first steps for cancer initiation could be epigenetic changes in key genes of one-carbon metabolism. Carbon 260-266 phorbol-12-myristate-13-acetate-induced protein 1 Homo sapiens 149-153 35023524-4 2022 Calculations suggest that despite a weaker carbon-sulfur bond, all the CS2 activations have higher reaction barriers than the CO2 capture, which could be attributed to electrostatic repulsion between FLPs and CS2 caused by the reversed polarity of C S in CS2 rather than the electrostatic attraction in CO2 capture. Carbon 43-49 chorionic somatomammotropin hormone 2 Homo sapiens 255-258 34715216-10 2022 These profiles demonstrated a positive correlation in the impacted turtles exposed to elevated PFAS with an enhanced purine metabolism, glycerophosphocholines and an innate immune response, which suggest an inflammation response, metabolic preservation and re-routing of central carbon metabolites. Carbon 279-285 phosphoribosylformylglycinamidine synthase Homo sapiens 95-99 35159761-0 2022 Highly Sensitive RNA-Based Electrochemical Aptasensor for the Determination of C-Reactive Protein Using Carbon Nanofiber-Chitosan Modified Screen-Printed Electrode. Carbon 104-110 C-reactive protein Homo sapiens 79-97 35023524-4 2022 Calculations suggest that despite a weaker carbon-sulfur bond, all the CS2 activations have higher reaction barriers than the CO2 capture, which could be attributed to electrostatic repulsion between FLPs and CS2 caused by the reversed polarity of C S in CS2 rather than the electrostatic attraction in CO2 capture. Carbon 43-49 chorionic somatomammotropin hormone 2 Homo sapiens 71-74 35023524-4 2022 Calculations suggest that despite a weaker carbon-sulfur bond, all the CS2 activations have higher reaction barriers than the CO2 capture, which could be attributed to electrostatic repulsion between FLPs and CS2 caused by the reversed polarity of C S in CS2 rather than the electrostatic attraction in CO2 capture. Carbon 43-49 chorionic somatomammotropin hormone 2 Homo sapiens 209-212 35132825-4 2022 Despite the change of carbon hybridization from sp2 to sp3 at the 9 and 10 positions of the anthracene units, the macrocyclic skeleton of the obtained compounds does not change its conformation. Carbon 22-28 Sp2 transcription factor Homo sapiens 48-51 35132825-4 2022 Despite the change of carbon hybridization from sp2 to sp3 at the 9 and 10 positions of the anthracene units, the macrocyclic skeleton of the obtained compounds does not change its conformation. Carbon 22-28 Sp3 transcription factor Homo sapiens 55-58 35163908-4 2022 The Mo species, moreover, led to a decrease in the (C15 + C17)/(C16 + C18) ratio, which is beneficial from the viewpoint of carbon atom economy. Carbon 124-130 Bardet-Biedl syndrome 9 Homo sapiens 70-73 34985245-1 2022 A superconducting joint architecture to join unreacted carbon-doped multifilament magnesium diboride (MgB2) wires with the functionality to screen external magnetic fields for magnetic resonance imaging (MRI) magnet applications is proposed. Carbon 55-61 secretoglobin family 2A member 1 Homo sapiens 102-106 35044566-8 2022 Notably, 14 up-regulated Kub sites in 11 proteins were enriched in the carbon fixation in photosynthetic organism pathway, and seven proteins (rbcL, PGK, GAPA, FBA5, ALDP, CFBP1 and GGAT) were down-regulated, indicating this pathway is tightly regulated by ubiquitination during leaf senescence. Carbon 71-77 rbcL Oryza sativa 143-147 35111765-0 2021 Cationic Polymer Brush-Modified Carbon Nanotube-Meditated eRNA LINC02569 Silencing Attenuates Nucleus Pulposus Degeneration by Blocking NF-kappaB Signaling Pathway and Alleviate Cell Senescence. Carbon 32-38 nuclear factor kappa B subunit 1 Homo sapiens 136-145 35042883-2 2022 In this context, enzymes capable of halogenating sp3 carbons with high stereo- and regiocontrol under benign conditions have attracted particular attention. Carbon 53-60 Sp3 transcription factor Homo sapiens 49-52 35020751-5 2022 Total carbon storage of the 364 refuges studied was 16.6 PgC, with a mean value 42,981 gCm-2. Carbon 6-12 progastricsin Homo sapiens 57-60 35021051-1 2022 The role of folate-dependent one carbon (1C) metabolism in CD4+ T cell polarization is incompletely understood. Carbon 33-39 CD4 molecule Homo sapiens 59-62 35046699-1 2022 Objective: The aim of this study is to assess the relationship between the single-nucleotide polymorphism (SNP) in the one-carbon metabolism pathway (MTR rs1805087; MTHFR rs1801133; ALDH1L1 rs2002287, rs2276731; DNMT1 rs16999593, rs2228611; DNMT3B rs2424908) and the risk of female breast cancer (BC) in a Chinese population. Carbon 123-129 aldehyde dehydrogenase 1 family member L1 Homo sapiens 182-189 35013253-3 2022 The results show that if emissions peak in 2025, the carbon neutrality goal calls for a 45-62% electrification rate, 47-78% renewable energy in primary energy supply, 5.2-7.9 TW of solar and wind power, 1.5-2.7 PWh of energy storage usage and 64-1,649 MtCO2 of negative emissions, and synergistically reducing approximately 80% of local air pollutants compared to the present level in 2050. Carbon 53-59 mitochondrially encoded cytochrome c oxidase II Homo sapiens 252-257 35013158-0 2022 Facile construction of fully sp2-carbon conjugated two-dimensional covalent organic frameworks containing benzobisthiazole units. Carbon 33-39 Sp2 transcription factor Homo sapiens 29-32 35337621-2 2022 Cleavage of a cobalt-carbon bond in organometallic B12 compound provide reactive intermediate for molecular transformations. Carbon 21-27 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 51-54 35071853-6 2022 A few species such as water-soluble organic and inorganic carbon (WSOC and WSIC), K+, SO4 2-, and NO3 -, owing to their hygroscopic nature, were efficiently scavenged, resulting in their lower concentration within the interstitial aerosol during fog episodes. Carbon 58-64 zinc finger protein, FOG family member 1 Homo sapiens 246-249 34915549-3 2022 Two-dimensional sp2 hybridized PHE-graphene might be a real support for SACs due to the potential energy well induced by its enneagon, hexagon and pentagon carbon rings. Carbon 156-162 Sp2 transcription factor Homo sapiens 16-19 35337631-3 2022 Few mechanisms that underlie the neuropsychiatric manifestations of B12 deficiency include alteration in one-carbon metabolism, genetic vulnerability, and alteration in folate metabolism. Carbon 109-115 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 68-71 35071191-3 2021 Then, the Ti-MOF-Pt has been used for glassy carbon electrode surface modification and consequently used for construction of a thrombin aptamer sensor. Carbon 45-51 coagulation factor II, thrombin Homo sapiens 127-135 35097255-2 2022 The findings indicate the different degree of sp2 and sp3 hybridized bonding structures of amorphous carbon collected from different industrial processes as well as heavy carbonaceous deposits generated by industrial catalysts. Carbon 101-107 Sp2 transcription factor Homo sapiens 46-49 35097255-2 2022 The findings indicate the different degree of sp2 and sp3 hybridized bonding structures of amorphous carbon collected from different industrial processes as well as heavy carbonaceous deposits generated by industrial catalysts. Carbon 101-107 Sp3 transcription factor Homo sapiens 54-57 35337621-4 2022 Vitamin B12 derivatives composed of corrinoid structure should form stable organometallic compound having a cobalt-carbon bond. Carbon 115-121 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 8-11 2558958-7 1989 ras1 ras2ts and ras1 cyr1ts mutants arrested in the G1 phase of the cell cycle at the restrictive temperature, and showed pleiotropic phenotypes to varying degrees even at a temperature permissive for growth (25 degrees), including slow growth, sporulation on rich media, increased accumulation of glycogen, impaired growth on nonfermentable carbon sources, heat-shock resistance, impaired growth on low concentrations of glucose, and lithium sensitivity. Carbon 342-348 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 5-9 2685568-5 1989 Expression of the PGK gene is found to be regulated according to the carbon source in the growth medium. Carbon 69-75 phosphoglycerate kinase Saccharomyces cerevisiae S288C 18-21 2685568-6 1989 PGK mRNA levels are high in yeast cells grown in glucose medium but low in yeast cells grown in media containing carbon sources such as pyruvate and acetate. Carbon 113-119 phosphoglycerate kinase Saccharomyces cerevisiae S288C 0-3 2568633-4 1989 Crossing of pas1-1 and pas2 strains resulted in diploid cells that had regained the ability to grow on oleic acid as sole carbon source and to form peroxisomes. Carbon 122-128 ubiquitin-protein ligase peroxin 12 Saccharomyces cerevisiae S288C 12-18 2775722-3 1989 The beta-carbon resonances of glycosylated Ser and Thr residues in intact and asialo mucin display considerable chemical shift heterogeneity which, upon the complete removal of carbohydrate, coalesces to single sharp resonances. Carbon 9-15 LOC100508689 Homo sapiens 85-90 2542226-5 1989 The product of the agp gene was required for growth on glucose-1-phosphate as the sole carbon source, a function for which alkaline phosphatase or other acid phosphatases cannot substitute. Carbon 87-93 glucose-1-phosphatase precursor Escherichia coli 19-22 2498272-4 1989 The stability to beta-lactamase was stronger with the increase of the number of the carbon atoms of N-4 position. Carbon 84-90 Beta lactamase Pseudomonas aeruginosa 17-31 35310605-12 2022 KEGG pathway analysis displayed that the dysregulated genes in specimens with high RIPK4 expressions were enriched in focal adhesion, proteoglycans in cancer, central carbon metabolism in cancer, and insulin secretion. Carbon 167-173 receptor interacting serine/threonine kinase 4 Homo sapiens 83-88 2768238-4 1989 The kinetics of the LCAT reaction were measured for p-nitrophenyl esters of fatty acids having up to six (C-6) carbons in length. Carbon 111-118 complement C6 Homo sapiens 106-109 2719924-8 1989 Acid quenching of a stiochiometric reaction between Ac(= S)CoA and citrate synthase following the transient quantitatively regenerates Ac(= S)CoA, indicating carbon-carbon bond formation had not yet occurred. Carbon 158-164 citrate synthase Homo sapiens 67-83 2719924-8 1989 Acid quenching of a stiochiometric reaction between Ac(= S)CoA and citrate synthase following the transient quantitatively regenerates Ac(= S)CoA, indicating carbon-carbon bond formation had not yet occurred. Carbon 165-171 citrate synthase Homo sapiens 67-83 2719924-14 1989 The data indicate that citrate synthase stabilizes the ionized form of Ac(= S)CoA by 5 kcal/mol relative to the un-ionized form, that the ionized dithioester is on the reaction pathway, and that below pH 8.3 the slow carbon-carbon bond forming reaction is responsible for the 10(6) decrease in Vmax caused by substituting sulfur for oxygen in the thioester carbonyl. Carbon 217-223 citrate synthase Homo sapiens 23-39 2719924-14 1989 The data indicate that citrate synthase stabilizes the ionized form of Ac(= S)CoA by 5 kcal/mol relative to the un-ionized form, that the ionized dithioester is on the reaction pathway, and that below pH 8.3 the slow carbon-carbon bond forming reaction is responsible for the 10(6) decrease in Vmax caused by substituting sulfur for oxygen in the thioester carbonyl. Carbon 224-230 citrate synthase Homo sapiens 23-39 16666552-7 1989 Intracellular CA also enhances the fixation of carbon in C. crispus. Carbon 47-53 CHC_T00010321001 Chondrus crispus 14-16 2663847-4 1989 Expression of mdhl- restores total cellular malate dehydrogenase activity to levels comparable to those in wild type cells and reverses the phenotype associated with strains containing MDH1 disruptions by restoring wild type rates of growth in media containing acetate as a carbon source. Carbon 274-280 malate dehydrogenase MDH1 Saccharomyces cerevisiae S288C 185-189 2900734-6 1988 Transferase pi selectively catalyzed the reaction of glutathione with the benzylic oxirane carbon (C-7) of (+/-)-styrene-7,8-oxide whereas alpha-epsilon preferentially catalyzed reaction with the terminal epoxide carbon (C-8) atom. Carbon 91-97 homeobox C8 Homo sapiens 221-224 3041241-2 1988 This response of PGK mRNA levels was not found on gluconeogenic carbon sources, and could be switched on or off subject to availability of fermentable carbon source. Carbon 64-70 phosphoglycerate kinase Saccharomyces cerevisiae S288C 17-20 3041241-2 1988 This response of PGK mRNA levels was not found on gluconeogenic carbon sources, and could be switched on or off subject to availability of fermentable carbon source. Carbon 151-157 phosphoglycerate kinase Saccharomyces cerevisiae S288C 17-20 2906224-2 1988 It seems that parent compounds with free hydroxyl groups at C-5, C-7, C-3", C-4" and additionally at C-3 have the highest activity. Carbon 60-61 complement C3 alpha chain Oryctolagus cuniculus 70-73 3346880-0 1988 Regio- and stereochemical studies on the alpha-carbon oxidation of (S)-nicotine by cytochrome P-450 model systems. Carbon 47-53 cytochrome P-450 Oryctolagus cuniculus 83-99 3346880-4 1988 The results of these studies are interpreted as additional evidence for the formation of a highly ordered complex between (S)-nicotine and cytochrome P-450 that directs the regio- and diasterioselective alpha-carbon oxidation of this substrate. Carbon 209-215 cytochrome P-450 Oryctolagus cuniculus 139-155 2906224-2 1988 It seems that parent compounds with free hydroxyl groups at C-5, C-7, C-3", C-4" and additionally at C-3 have the highest activity. Carbon 60-61 complement C3 alpha chain Oryctolagus cuniculus 101-104 3145192-8 1988 A ras1- yeast strain with a chromosomal RAS2 gene harbouring the three mutations together did not grow at any temperature using non-fermentable carbon sources, but it was able to grow on glucose at 30 degrees C, and not at 37 degrees C. The mutated proteins were much less effective than the wild-type RAS2 protein in the stimulation of adenylate cyclase, but were efficiently expressed in vivo. Carbon 144-150 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 40-44 2854260-2 1987 The intact form of protein C inhibitor was predicted with an alpha-carbon model based on its hydrophilicity and hydrogen bond pattern. Carbon 67-73 serpin family A member 5 Homo sapiens 19-38 3421956-3 1988 The second-order rate constants, k-1, obtained are 1.34 x 10(-1) M-1s-1 for 1, 2.42 x 10(-1) M-1s-1 for 2, and 3.65 x 10(-1) M-1s-1 for 3 at 25.0 degrees C. The result indicates that the rate constants increase as the total electron donating capacity of the alkyl substituents at alpha-carbon atom of hydroperoxides increases. Carbon 286-292 keratin 1 Homo sapiens 33-36 3653391-0 1987 Assignment of hyperfine shifted haem methyl carbon resonances in paramagnetic low-spin met-cyano complex of sperm whale myoglobin. Carbon 44-50 myoglobin Physeter catodon 120-129 3653391-1 1987 The hyperfine shifted resonances arising from all four individual haem carbons of the paramagnetic low-spin met-cyano complex of sperm whale myoglobin have been clearly identified and assigned for the first time with the aid of 1H-13C heteronuclear chemical shift correlated spectroscopy. Carbon 71-78 myoglobin Physeter catodon 141-150 3183521-2 1988 The direct oxidation-dehydrogenation at C-3 is applicable to other cholanoates (hyodeoxycholic, chenodeoxycholic, ursodeoxycholic, deoxycholic, and cholic) when the hydroxyl groups at C-6, C-7, or C-12 are protected. Carbon 40-41 complement C6 Homo sapiens 184-187 2823123-8 1987 Derepression of CYC7 expression in a medium containing nonfermentable carbon sources depended upon sequences between -354 and -295. Carbon 70-76 cytochrome c isoform 2 Saccharomyces cerevisiae S288C 16-20 3379962-4 1988 Together with previous results obtained with 22-amino and 22-hydroxy analogues, these findings provide support for the proximity of C-22 and the heme-iron of cytochrome P450scc in the enzyme-substrate complex. Carbon 132-133 cholesterol side-chain cleavage enzyme, mitochondrial Bos taurus 158-176 3455050-5 1987 The C-3 function may be carbonyl, 3 beta-hydroxy or 3 beta-acetoxy when associated with C-4 or C-4,6 unsaturation. Carbon 88-89 complement C3 Canis lupus familiaris 4-7 3325498-1 1987 When baker"s yeast grown aerobically on ethanol as a carbon source was anaerobically cultured in a medium containing glucose, the activity of a cytoplasmic fumarate reductase irreversibly catalyzing the conversion of fumarate to succinate increased, reaching about 3 times the original activity after 12 h, while the activity of succinate dehydrogenase was almost lost after 10 h. These results indicate that the citrate cycle is partially modified to become a reductive pathway leading to succinate during the anaerobic cultivation. Carbon 53-59 fumarate reductase Saccharomyces cerevisiae S288C 156-174 2431707-0 1986 Toward the complete assignment of the carbon nuclear magnetic resonance spectrum of the basic pancreatic trypsin inhibitor. Carbon 38-44 cysteine rich secretory protein LCCL domain containing 2 Homo sapiens 105-122 2431707-1 1986 A total of 54 of the 58 alpha-carbon resonances and numerous side-chain carbon signals were individually assigned in the basic pancreatic trypsin inhibitor by using two-dimensional heteronuclear correlated and relayed coherence transfer spectroscopy with proton detection. Carbon 30-36 cysteine rich secretory protein LCCL domain containing 2 Homo sapiens 138-155 2431707-1 1986 A total of 54 of the 58 alpha-carbon resonances and numerous side-chain carbon signals were individually assigned in the basic pancreatic trypsin inhibitor by using two-dimensional heteronuclear correlated and relayed coherence transfer spectroscopy with proton detection. Carbon 72-78 cysteine rich secretory protein LCCL domain containing 2 Homo sapiens 138-155 16665030-5 1986 Despite this significantly greater level of PPDK in the diploid species, the actual amount of PPDK could still supply only a limited amount of the enzyme activity necessary to provide phosphoenolpyruvate (PEP) for any putative intracellular C(4) carbon shuttle providing carbon to RuBPC. Carbon 246-252 pyruvate, phosphate dikinase 1, chloroplastic Triticum aestivum 94-98 3124004-4 1987 The substitution of deuterium for hydrogens in the alpha-carbon of the alkyl-side chain of phenylethylamines decreases the rate of deamination by MAO. Carbon 57-63 monoamine oxidase A Rattus norvegicus 146-149 16665030-5 1986 Despite this significantly greater level of PPDK in the diploid species, the actual amount of PPDK could still supply only a limited amount of the enzyme activity necessary to provide phosphoenolpyruvate (PEP) for any putative intracellular C(4) carbon shuttle providing carbon to RuBPC. Carbon 271-277 pyruvate, phosphate dikinase 1, chloroplastic Triticum aestivum 94-98 3733706-1 1986 Possible regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by shunted mevalonate carbon. Carbon 102-108 HMG Coenzyme A reductase Drosophila melanogaster 23-70 3473478-5 1987 Combined simulations of both the relaxation times and the quadrupolar echo line shapes as a function of pulse spacing allowed unambiguous assignment of the various motional modes and a consistent interpretation of data from lipids labeled on the C-6, C-13, and C-14 positions of the sn-2 chain. Carbon 0-1 complement C6 Homo sapiens 246-249 3013722-2 1986 Strains with disruptions of the RAS2 gene fail to grow efficiently on nonfermentable carbon sources. Carbon 85-91 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 32-36 16347020-5 1986 Experiments with [C]EDB showed that EDB was converted to approximately equal amounts of CO(2) and apparent cellular carbon; only small amounts of added C were not attributable to these products or unreacted EDB. Carbon 116-122 vesicle associated membrane protein 8 Homo sapiens 36-39 16347020-5 1986 Experiments with [C]EDB showed that EDB was converted to approximately equal amounts of CO(2) and apparent cellular carbon; only small amounts of added C were not attributable to these products or unreacted EDB. Carbon 116-122 vesicle associated membrane protein 8 Homo sapiens 36-39 3816805-0 1987 High-resolution solid-state 13C-NMR study of carbons C-5 and C-12 of the chromophore of bovine rhodopsin. Carbon 45-52 complement C5 Bos taurus 53-56 2931900-3 1985 Inactive acyl plasmin was deacylated with the constant rate k3 = 3.10(-4) c-1 (r1/2 = 40 min) at pH 7.4 and 37 degrees. Carbon 3-4 plasminogen Homo sapiens 14-21 3102945-2 1987 When this strain was transformed with the GAL4 positive regulatory gene of Saccharomyces cerevisiae it was able to grow on lactose or galactose as the sole carbon source. Carbon 156-162 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 42-46 2412116-7 1985 Neuraminidase-treated cells incorporated sialic acid or its 7-carbon analog, 5-acetamido-3,5-dideoxy-L-arabino-2-heptulosonic acid (AcNeu7) from sialylated compounds such as fetuin or sialyl-lactose but did not incorporate free sialic acid. Carbon 62-68 neuraminidase 1 Homo sapiens 0-13 3820165-8 1987 Carbon particles were deposited in the walls of post-capillary venules and leucocytes migrated through open interendothelial cell gaps in hCG-treated animals. Carbon 0-6 hypertrichosis 2 (generalised, congenital) Homo sapiens 138-141 6135577-3 1983 A stable isotope-labeling study, in which [2-14C]caffeine in a 1:1 mixture of unlabeled caffeine and [1,3-15N-8-13C] caffeine was administered to subjects, demonstrated that the C-8 carbon of caffeine was lost during the biotransformation to A1. Carbon 182-188 homeobox C8 Homo sapiens 178-181 2892185-2 1987 The 5-O-phosphonomethyl analog of ATP (ATPc) and its interaction with different enzymes, catalysing synthesis of C-O-, C-S-, C-N- and C-C-bond were investigated. Carbon 113-114 ATPase phospholipid transporting 8A2 Homo sapiens 34-37 6300668-1 1983 2 human hepatoma cell lines (C-HC-4 and C-HC-20), in which aryl hydrocarbon hydroxylase activity was induced with benz[alpha]anthracene in vitro to about 140- and 64-fold of the respective basal levels, yielded an increased frequency of sister-chromatid exchanges (SCEs) when exposed to benzo[alpha]pyrene (BP), 7,12-dimethylbenz[alpha]anthracene and 3-methylcholanthrene in vitro. Carbon 29-30 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 59-87 6130090-4 1983 The extent of maximum stimulation of the EF-Tu GTPase in the presence of ribosomes varies moderately depending on the aa-tRNA species; a clear dependence on the nature of the aminoacyl side chain is observed in the effects of their respective C-C-A-aa fragments tested (C-C-A-Arg, C-C-A-Val, C-C-A-Phe, C-C-A-Met, C-C-A-Lys). Carbon 243-244 eukaryotic translation elongation factor 1 alpha 1 Homo sapiens 41-46 6130090-4 1983 The extent of maximum stimulation of the EF-Tu GTPase in the presence of ribosomes varies moderately depending on the aa-tRNA species; a clear dependence on the nature of the aminoacyl side chain is observed in the effects of their respective C-C-A-aa fragments tested (C-C-A-Arg, C-C-A-Val, C-C-A-Phe, C-C-A-Met, C-C-A-Lys). Carbon 245-246 eukaryotic translation elongation factor 1 alpha 1 Homo sapiens 41-46 6130090-4 1983 The extent of maximum stimulation of the EF-Tu GTPase in the presence of ribosomes varies moderately depending on the aa-tRNA species; a clear dependence on the nature of the aminoacyl side chain is observed in the effects of their respective C-C-A-aa fragments tested (C-C-A-Arg, C-C-A-Val, C-C-A-Phe, C-C-A-Met, C-C-A-Lys). Carbon 245-246 eukaryotic translation elongation factor 1 alpha 1 Homo sapiens 41-46 6130090-4 1983 The extent of maximum stimulation of the EF-Tu GTPase in the presence of ribosomes varies moderately depending on the aa-tRNA species; a clear dependence on the nature of the aminoacyl side chain is observed in the effects of their respective C-C-A-aa fragments tested (C-C-A-Arg, C-C-A-Val, C-C-A-Phe, C-C-A-Met, C-C-A-Lys). Carbon 245-246 eukaryotic translation elongation factor 1 alpha 1 Homo sapiens 41-46 2776860-3 1989 In contrast lauroyl-L-Ala-gamma-D-Glu-DD-A2pmNH2 (RP 53.204), which only differs by the configuration of the two chiral carbons of A2pm (diaminopimelic acid) and is not an immunomodulating agent, failed to protect against poisoning by paracetamol and had no effect on the level of hepatic cytochrome P-450 or the microsomal CCl4-induced lipid peroxidation. Carbon 120-127 G protein-coupled receptor 162 Mus musculus 41-48 6130090-4 1983 The extent of maximum stimulation of the EF-Tu GTPase in the presence of ribosomes varies moderately depending on the aa-tRNA species; a clear dependence on the nature of the aminoacyl side chain is observed in the effects of their respective C-C-A-aa fragments tested (C-C-A-Arg, C-C-A-Val, C-C-A-Phe, C-C-A-Met, C-C-A-Lys). Carbon 245-246 eukaryotic translation elongation factor 1 alpha 1 Homo sapiens 41-46 2892185-2 1987 The 5-O-phosphonomethyl analog of ATP (ATPc) and its interaction with different enzymes, catalysing synthesis of C-O-, C-S-, C-N- and C-C-bond were investigated. Carbon 113-114 ATPase phospholipid transporting 8A2 Homo sapiens 39-43 6130090-4 1983 The extent of maximum stimulation of the EF-Tu GTPase in the presence of ribosomes varies moderately depending on the aa-tRNA species; a clear dependence on the nature of the aminoacyl side chain is observed in the effects of their respective C-C-A-aa fragments tested (C-C-A-Arg, C-C-A-Val, C-C-A-Phe, C-C-A-Met, C-C-A-Lys). Carbon 245-246 eukaryotic translation elongation factor 1 alpha 1 Homo sapiens 41-46 6130090-4 1983 The extent of maximum stimulation of the EF-Tu GTPase in the presence of ribosomes varies moderately depending on the aa-tRNA species; a clear dependence on the nature of the aminoacyl side chain is observed in the effects of their respective C-C-A-aa fragments tested (C-C-A-Arg, C-C-A-Val, C-C-A-Phe, C-C-A-Met, C-C-A-Lys). Carbon 245-246 eukaryotic translation elongation factor 1 alpha 1 Homo sapiens 41-46 3021640-4 1986 In the orthorhombic single crystal, we observed interaction of the unpaired electron, which is delocalized on the carbons C(3), C(4) and C(5) with one alpha-proton in position 4 and with four nonequivalent beta-protons connected with the carbon atoms C(2) and C(6). Carbon 114-120 complement C6 Homo sapiens 260-264 6179550-2 1982 The crystal structure and a 96-ps molecular dynamics simulation used to analyze structural and motional contributions to spin-lattice (T1) relaxation times of phenylalanine and tyrosine C gamma carbons of the pancreatic trypsin inhibitor. Carbon 194-201 cysteine rich secretory protein LCCL domain containing 2 Homo sapiens 220-237 2761264-5 1989 Since the six-carbon side chain analogue had the highest relative PgR affinity (38% of the affinity of R5020, using PgR from T47D human breast cancer cells), it was selected for preparation of the 125I form by radiohalogen exchange of a omega-bromoalkynyl precursor with carrier-free Na125I. Carbon 14-20 progesterone receptor Homo sapiens 66-69 2673929-2 1989 When Escherichia coli strains (that are unable to grow on glucose due to the absence of functional zwf (G6PD-) and pgi genes) were transformed with this plasmid (pAC1), they were able to grow on glucose as sole carbon source. Carbon 211-217 dual specificity phosphatase 2 Homo sapiens 162-166 6288234-0 1982 S-Adenosyl-L-methionine is a carbon donor in the conversion of benzo[alpha]pyrene to 6-hydroxymethylbenzo[alpha]pyrene by rat liver S-9. Carbon 29-35 ribosomal protein S9 Homo sapiens 132-135 3013258-1 1986 Aflatoxins B1, B2, G1, G2, and M1 have been evaluated for activity toward cytochrome oxidase in isolated rat liver mitochondria employing ferrocytochrome c and p-phenylene diamine as reductants. Carbon 59-60 UDP glucuronosyltransferase family 1 member A1 Rattus norvegicus 11-33 6288234-3 1982 We now report that S-adenosyl-L-methionine (SAM) can serve as a carbon donor in the metabolic formation of 6-hydroxymethylbenzo[alpha]pyrene from benzo[alpha]pyrene by the S-9 fraction of rat liver. Carbon 64-70 ribosomal protein S9 Homo sapiens 172-175 3023912-8 1986 However, transcription of CIT1 but not of CIT2 was derepressed in medium containing a nonfermentable carbon source. Carbon 101-107 citrate (Si)-synthase CIT1 Saccharomyces cerevisiae S288C 26-30 7082318-4 1982 The incorporation of the 14C label from [1-14C]pyruvate into the tricarboxylic acid-cycle intermediates points to a carbon input from pyruvate via enzymes in addition to pyruvate dehydrogenase and citrate synthase. Carbon 116-122 citrate synthase Rattus norvegicus 197-213 6794031-1 1981 The in vivo flux of carbon through the pentose shunt is investigated as a function of different 6-phosphogluconate dehydrogenase (6Pgd) and glucose-6-phosphate dehydrogenase (G6pd) genotypes by using differential radioactive labeling of the C-1 and C-6 positions of glucose. Carbon 20-26 anon-17Ca Drosophila melanogaster 241-252 2738142-1 1989 A macroporous carbon sorbent, packed into disposable columns (Separcol-Carb), was investigated for the off-line preconcentration of short-chain fatty acids from drinking water in conjunction with their determination by capillary isotachophoresis (ITP). Carbon 14-20 syntaxin 8 Homo sapiens 71-75 3520568-0 1986 Carbon source regulation of RAS1 expression in Saccharomyces cerevisiae and the phenotypes of ras2- cells. Carbon 0-6 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 94-98 16666695-1 1989 The regulatory metabolite fructose-2,6-bisphosphate (Fru-2,6-P(2)) has an important function in controlling the intermediary carbon metabolism of leaves. Carbon 125-131 zinc finger and BTB domain containing 22 Homo sapiens 53-56 6787035-4 1981 Furthermore, after the nucleotide had disappeared in cells cultivated in mS6(C) upon exhaustion of the carbon source, it could be reformed in the sporulating cells by addition of glucose to the medium. Carbon 103-109 minisatellites detected by probe MMS6 Mus musculus 73-76 6778858-3 1980 In the exchange reaction of the carboxyl carbon of glycine wih CO2 catalyzed by the purified P-protein in the presence of H-protein, the pH optimum was 6.7, Km for glycine was 6.6 mM, and Km for H-protein was 7.4 microM. Carbon 41-47 myosin binding protein H Rattus norvegicus 122-131 3520568-1 1986 Transcriptional analysis of the yeast RAS genes in different culture conditions suggests that the inability of ras2 mutants to grow in nonfermentable carbon sources results from the regulation of RAS1 mRNA expression. Carbon 150-156 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 111-115 6778858-3 1980 In the exchange reaction of the carboxyl carbon of glycine wih CO2 catalyzed by the purified P-protein in the presence of H-protein, the pH optimum was 6.7, Km for glycine was 6.6 mM, and Km for H-protein was 7.4 microM. Carbon 41-47 myosin binding protein H Rattus norvegicus 195-204 2915693-3 1989 Although Ca2+ is not directly involved in the catalytic mechanism and is 16.6 A away from the alpha-carbon atoms of the catalytic triad Asp 39-His 69-Ser 224, the activity of proteinase K towards the synthetic substrate succinyl-Ala-Ala-Ala-p-nitroanilide drops slowly to approximately 20% of its original value when it is depleted of Ca2+. Carbon 100-106 endogenous retrovirus group K member 7 Homo sapiens 175-185 3520568-4 1986 This can explain the inability of ras2- cells to grow on nonfermentable carbon sources. Carbon 72-78 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 34-38 3959080-1 1986 Silk fibroin with the alanyl carboxyl carbon enriched with 13C was obtained by giving a diet containing 13C-enriched alanine to the larvae of Bombyx mori and Antheraea pernyi at the fifth instar. Carbon 38-44 fibroin light chain Bombyx mori 5-12 2540420-8 1989 The regulation of PET494 expression by carbon source was also examined. Carbon 39-45 Pet494p Saccharomyces cerevisiae S288C 18-24 2540420-11 1989 PET494 transcript levels varied over a fourfold range in response to different carbon sources. Carbon 79-85 Pet494p Saccharomyces cerevisiae S288C 0-6 3062377-6 1988 When the GAL11 locus was disrupted by insertion of the URA3 gene, the resulting yeast cells (gal11::URA3) exhibited phenotypes almost identical to those of the gal11 strains, with respect to both galactose utilization and growth on nonfermentable carbon sources. Carbon 247-253 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 55-59 6446938-13 1980 It is concluded that a minimum of 16 carbon atoms in each chain are required to organize a bilayer structurable to maintain the ATPase complex conformation and to sustain the transmembrane position of the whole assembly. Carbon 37-43 dynein axonemal heavy chain 8 Homo sapiens 128-134 707364-2 1978 Most communities form in mucous layers on the surfaces, where some microbes in the communities may utilize the mucin as a source of carbon and energy. Carbon 132-138 LOC100508689 Homo sapiens 111-116 4083893-5 1985 Dimethylation of the methylene bridge carbon of BD to give 2,2-dimethyl-5-t-butyl-1,3-benzodioxole (DBD) blocks the formation of NADPH-reduced Type III metabolite-P-450 complexes in vitro, and diminishes but does not abolish the ability of the compound to induce P-450b. Carbon 38-44 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 263-269 788780-0 1976 A carbon-13 nuclear magnetic resonance study of hyperactive and hypoactive derivatives of luteinizing hormone-releasing hormone: des-Gly-NH210-[DLeu6]LH-RH ethylamide and des-Gly-NH210-[L-Leu6]LH-RH ethylamide. Carbon 2-8 gonadotropin releasing hormone 1 Homo sapiens 150-155 3043463-6 1988 A superposition of the structures of poplar plastocyanin and bovine Cu-Zn superoxide dismutase (SOD) showed that 68 out of 99 alpha-carbons in plastocyanin overlapped with corresponding atoms in SOD with a rms distance of 2.99 A. Carbon 132-139 superoxide dismutase [Cu-Zn] Bos taurus 68-94 2988366-0 1985 Carbon nuclear magnetic resonance spectra of oligosaccharides isolated from human milk and ovarian cyst mucin. Carbon 0-6 LOC100508689 Homo sapiens 104-109 3656290-3 1987 Carbon-labelling, interstitial fluid volume and leucocyte migration were all reduced in rats treated with hCG+ terbutaline compared to the values in animals given hCG only. Carbon 0-6 hypertrichosis 2 (generalised, congenital) Homo sapiens 106-109 137518-3 1976 The carnitine concentration correlated positively and statistically significantly with the activities of 3-OH-acyl-CoA dehydrogenase and citrate synthase, with the incorporation rate of palmitate-carbon into CO2, and the incorporation rate of glucose-carbon into lactate in the muscle tissue. Carbon 196-202 citrate synthase Homo sapiens 137-153 8429-4 1976 Both dihydropteridine reductase and phenylalanine hydroxylase activities were found to be higher in cells adapted to a medium containing L-phenylalanine or L-tyrosine as the sole carbon source than in those grown in L-asparagine. Carbon 179-185 phenylalanine hydroxylase Homo sapiens 36-61 3302674-5 1987 The mutations yielded a Ras2- phenotype with respect to the ability of the resultant mutants to grow on nonfermentable carbon sources and to complement ras1- mutants. Carbon 119-125 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 24-28 3978085-1 1985 The carbon-13 NMR spectrum of oxaloacetate bound in the active site of citrate synthase has been obtained at 90.56 MHz. Carbon 4-10 citrate synthase Homo sapiens 71-87 3302676-2 1987 By utilizing growth conditions that favor either transcriptional induction (galactose-carbon source) or repression (glucose-carbon source) from the GAL1 promoter, centromere function can be switched off or on, respectively. Carbon 86-92 galactokinase Saccharomyces cerevisiae S288C 148-152 1169067-0 1975 Alpha-carbon coordinates for bovine Cu,Zn superoxide dismutase. Carbon 6-12 superoxide dismutase [Cu-Zn] Bos taurus 36-62 3302676-2 1987 By utilizing growth conditions that favor either transcriptional induction (galactose-carbon source) or repression (glucose-carbon source) from the GAL1 promoter, centromere function can be switched off or on, respectively. Carbon 124-130 galactokinase Saccharomyces cerevisiae S288C 148-152 6643474-7 1983 A quantitative relationship between fatty acyl chain length and the extent of maximal activation of LpL by apoC-II was observed: the logarithm of the activation factor is a linear function of the number of carbon atoms of a single fatty acyl chain of the substrates. Carbon 206-212 lipoprotein lipase Bos taurus 100-103 2434233-1 1987 Somatomedin C (Sm-C; insulin-like growth factor I; IGF-I) is a polypeptide (Mr 7649), often dependent on growth hormone (GH), with trophic effects on several different tissues. Carbon 12-13 gonadotropin releasing hormone receptor Rattus norvegicus 105-119 4634828-4 1972 The carbon skeletons of formate and succinate were shown to arise from the C-2 and the C-3-C-6 atoms of the heterocyclic ring respectively by using N-methyl[2,3-(14)C(2)]isonicotinate. Carbon 4-10 complement C6 Homo sapiens 91-94 2434233-1 1987 Somatomedin C (Sm-C; insulin-like growth factor I; IGF-I) is a polypeptide (Mr 7649), often dependent on growth hormone (GH), with trophic effects on several different tissues. Carbon 12-13 gonadotropin releasing hormone receptor Rattus norvegicus 121-123 6643474-7 1983 A quantitative relationship between fatty acyl chain length and the extent of maximal activation of LpL by apoC-II was observed: the logarithm of the activation factor is a linear function of the number of carbon atoms of a single fatty acyl chain of the substrates. Carbon 206-212 apolipoprotein C2 Bos taurus 107-114 16349813-7 1968 Approximately 90% removal of the carbon source (expressed as chemical oxygen demand, COD) was attained with a low level of supplemental nitrogen (COD/N = 70:1) and a fairly low reactor detention time (4 hr). Carbon 33-39 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 85-88 16349813-7 1968 Approximately 90% removal of the carbon source (expressed as chemical oxygen demand, COD) was attained with a low level of supplemental nitrogen (COD/N = 70:1) and a fairly low reactor detention time (4 hr). Carbon 33-39 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 146-149 6313677-4 1983 These data indicate that the LTA-hydrolase requires not only the three double bonds of the triene but also the double bond at C-14 to efficiently convert LTA to LTB. Carbon 126-127 lymphotoxin beta Rattus norvegicus 161-164 14247500-2 1964 THE EFFECT OF A MURINE LEUKEMIA ON ENZYMES OF ONE-CARBON METABOLISM AND ON PHOSPHOMONOESTERASES. Carbon 50-56 oncofetal antigen Mus musculus 11-15 3325336-2 1987 This method is based on our observation that P. pastoris cannot use sucrose as the sole carbon source (Suc-) and that introduction of the invertase gene (SUC2) of Saccharomyces cerevisiae renders P. pastoris Suc+. Carbon 88-94 beta-fructofuranosidase SUC2 Saccharomyces cerevisiae S288C 154-158 2943981-3 1986 In the present series, the dopamine D2-receptor agonists have the S-configuration at the nitrogen-bearing carbon (C2), whereas the only established D2-receptor antagonist, 1S,2R-5-hydroxyl-1-methyl-2-(di-n-propylamino)tetralin (1S,2R-UH-242), has the opposite absolute configuration at C2. Carbon 106-112 dopamine receptor D2 Homo sapiens 27-47 6363430-8 1983 In addition, the expression of the cdc27-47 execution point was modified by both genetic and environmental factors, being affected by carbon source, by the petite condition, and by genetic background. Carbon 134-140 anaphase promoting complex subunit CDC27 Saccharomyces cerevisiae S288C 35-40 3008818-4 1986 The experimental broadening fit a model in which c-551 is in intermediate or fast exchange between free solution and a complex with cd1, with an association constant for the complex in excess of 10(4) M-1. Carbon 46-47 CD1c molecule Homo sapiens 132-135 16561537-0 1948 The Utilization of Carbon Compounds by Some Actinomycetales as an Aid for Species Determination. Carbon 19-25 activation induced cytidine deaminase Homo sapiens 66-69 7155295-18 1982 The second operation to the right C-C-SDH was performed from one year later after the first craniotomy. Carbon 34-35 serine dehydratase like Homo sapiens 36-41 34042971-4 2021 When compared to previously identified S. cerevisiae genes involved in lactic acid transport, expression of ATO3T284C was able to facilitate the highest growth rate (0.15 +- 0.01 h-1) on this carbon source. Carbon 192-198 putative ammonium permease ATO3 Saccharomyces cerevisiae S288C 108-112 2420275-4 1986 At intermediate MBP/PG ratios, two components in slow exchange on the NMR time scale (bulk PG and a protein-induced PG domain) were observed for the 13C resonance of the head group carbon atom adjacent to phosphate. Carbon 181-187 myelin basic protein Homo sapiens 16-19 16453671-2 1986 The presence of the inducible GAL1-10 upstream activation site (UAS) allows us to regulate differentially by carbon sources the transcription of the zein gene both under the plant promoter and under the yeast CYC-1 promoter. Carbon 109-115 galactokinase Saccharomyces cerevisiae S288C 30-34 34033910-10 2021 After stimulation by Poly I:C, OnCD226 expression was extremely significant (p < 0.01) at 72 h and 96 h, the peak was observed at 96 h. After stimulation by Keyhole limpet hemocyanin (KLH), a classical T cell-dependent antigen, the expression of OnCD226 was significantly up-regulated in blood, head kidney, spleen, and thymus. Carbon 28-29 CD226 antigen Oreochromis niloticus 31-38 34033910-10 2021 After stimulation by Poly I:C, OnCD226 expression was extremely significant (p < 0.01) at 72 h and 96 h, the peak was observed at 96 h. After stimulation by Keyhole limpet hemocyanin (KLH), a classical T cell-dependent antigen, the expression of OnCD226 was significantly up-regulated in blood, head kidney, spleen, and thymus. Carbon 28-29 CD226 antigen Oreochromis niloticus 246-253 7085659-2 1982 The labeling procedure cleaves the sialic acids to a neuraminidase-sensitive 7-carbon derivative, 5-acetamido-3,5-dideoxy-L-arabino-heptulosonic acid, termed AcNeu7 (Van Lenten, L., and Ashwell, G. (1971) J. Biol. Carbon 79-85 neuraminidase 1 Homo sapiens 53-66 3935271-2 1985 injection of growth hormone-releasing factor (GRF) increases the height of the 3,4-dihydroxyphenylacetic acid oxidation peak (peak 2) but does not change 5-hydroxyindole extracellular content (peak 3) in the arcuate nucleus of the hypothalamus, both peaks being recorded by the differential pulse voltammetry technique using a single specifically pretreated monopyrolytic carbon fibre electrode. Carbon 372-378 growth hormone releasing hormone Rattus norvegicus 13-44 3935271-2 1985 injection of growth hormone-releasing factor (GRF) increases the height of the 3,4-dihydroxyphenylacetic acid oxidation peak (peak 2) but does not change 5-hydroxyindole extracellular content (peak 3) in the arcuate nucleus of the hypothalamus, both peaks being recorded by the differential pulse voltammetry technique using a single specifically pretreated monopyrolytic carbon fibre electrode. Carbon 372-378 growth hormone releasing hormone Rattus norvegicus 46-49 33957043-2 2021 We here report the implantation of Co-SAs into hollow carbon spheres (Co-SAs-HCS) via a facile wet-chemistry strategy followed by controlled pyrolysis. Carbon 54-60 holocarboxylase synthetase Homo sapiens 77-80 7074014-2 1982 We identified the one-carbon units present in rat liver folates within each of the liver folate polyglutamate groups, the folate penta-, hexa-, and heptaglutamates. Carbon 22-28 hexosaminidase subunit alpha Rattus norvegicus 137-141 33931592-5 2021 Therefore, selective inhibition of PHGDH may represent a new therapeutic strategy for over-expressing PHGDH tumours, owing to its downstream inhibition of essential biomass production such as one-carbon units and nucleotides. Carbon 196-202 phosphoglycerate dehydrogenase Homo sapiens 35-40 33931592-5 2021 Therefore, selective inhibition of PHGDH may represent a new therapeutic strategy for over-expressing PHGDH tumours, owing to its downstream inhibition of essential biomass production such as one-carbon units and nucleotides. Carbon 196-202 phosphoglycerate dehydrogenase Homo sapiens 102-107 6120236-0 1981 Selective and potent beta 2-adrenoceptor agents within the tetrahydroisoquinoline class: effect of methyl substitution at the benzylic carbon of the 1-(3,4,5-trimethoxybenzyl) group of trimetoquinol. Carbon 135-141 beta-2 adrenergic receptor Cavia porcellus 21-40 4035563-7 1985 The Hepatic-Aid diet increased (p less than 0.05) nitrogen and carbon fluxes significantly more than did the standard diet. Carbon 63-69 activation induced cytidine deaminase Homo sapiens 12-15 6975421-6 1981 Both BV1 and B. gazogenes are able to grow utilizing xylose, cellobiose or arabinose, products of plant biosynthesis, as sole carbon sources. Carbon 126-132 endogenous ecotropic MuLV 2 Mus musculus 5-8 3895224-2 1985 An insertion mutation in RAS2 (ras2::LEU2) does not affect growth on glucose based media but it does prevent growth on media with pyruvate or other noncarbohydrate carbon sources. Carbon 164-170 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 25-29 3895224-2 1985 An insertion mutation in RAS2 (ras2::LEU2) does not affect growth on glucose based media but it does prevent growth on media with pyruvate or other noncarbohydrate carbon sources. Carbon 164-170 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 31-41 7011505-6 1980 As judged by comparison with organisms in which this enzyme serves as part of the principal carbon-handling pathway, L-serine deaminase activity is present in E. coli extracts in physiologically significant amounts. Carbon 92-98 serine dehydratase Homo sapiens 117-135 4031656-0 1985 Synthesis of C-22, C-23-3H-labeled 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestane. Carbon 13-14 nucleolin Homo sapiens 19-23 4031656-1 1985 This report describes an efficient synthesis of C-22, C-23-(3)H-labeled 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane. Carbon 48-49 nucleolin Homo sapiens 54-58 4031656-3 1985 Synthesis of C-22, C-23-(3)H-labeled 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane. Carbon 13-14 nucleolin Homo sapiens 19-23 3892149-11 1985 In the reduced group the probability of CCR at 54 months for standard risk patients is 0,86 +/- 0,06; for high-risk patients 0,60 +/- 0,09; for patients with c-ALL 0,73 +/- 0,08; for patients with c/T-ALL 1,0 +/- 0,0; for patients with pre-T or T-ALL 0,58 +/- 0,2 and for patients with AUL 0,45 +/- 0,25. Carbon 11-12 TNF superfamily member 13b Homo sapiens 199-208 17745959-1 1980 Five carbynes (triply bonded allotropes of carbon) have been found by electron diffraction in the Allende and Murchison carbonaceous chondrites: carbon VI, VIII, X, XI, and (tentatively) XII. Carbon 43-49 cytochrome c oxidase subunit 8A Homo sapiens 156-160 3994716-0 1985 Iron-57 chemical shifts in carbonyl myoglobin and its model complexes determined by iron-57-carbon-13 double resonance. Carbon 27-33 myoglobin Physeter catodon 36-45 385314-11 1979 Enzymes underlying carbon-catabolite inactivation in wild-type cells (a mechanism proposed to be possibly triggered by proteinase B) such as cytoplasmic malate dehydrogenase, fructose-1,6-bisphosphatase, phosphoenolpyruvate carboxykinase and isocitrate lyase, are inactivated also in the mutant. Carbon 19-25 proteinase B Saccharomyces cerevisiae S288C 119-131 3970939-1 1985 Resonance Raman scattering experiments on CO-complexed cytochrome P-450scc from bovine adrenocortical mitochondria demonstrate the simultaneous enhancement of v(Fe-CO) stretching and bound v(C-O) stretching frequencies at 477 and 1953 cm-1, respectively. Carbon 42-43 cholesterol side-chain cleavage enzyme, mitochondrial Bos taurus 66-74 222733-0 1979 Arylsulfatase in Salmonella typhimurium: detection and influence of carbon source and tyramine on its synthesis. Carbon 68-74 putative arylsulfatase Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 0-13 6546486-6 1984 These results indicate that when the lactonization at C-23 and C-26 positions of various vitamin D3 derivatives occurred the stereochemical configuration at their C-23 and/or C-25 positions was not changed and the difference of the stereochemical configurations determined the rate of lactonization. Carbon 54-55 nucleolin Homo sapiens 163-167 222733-5 1979 The uptake of [14C]tyramine and arylsulfatase synthesis were initiated during the second phase of a diauxie growth response, when the organism was cultured with different carbon sources. Carbon 171-177 putative arylsulfatase Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 32-45 16592469-6 1977 There is approximately a 20- to 40-ppm shielding of the (13)C chemical shifts of five- and six-coordinated carbons, compared with those of four valent carbons, with a simultaneous general increase of J(C-H) coupling constants. Carbon 107-114 joining chain of multimeric IgA and IgM Homo sapiens 200-205 6393522-1 1984 Short-lived radioactive carbon, 11C, (T 1/2 = 20 min) was incorporated into an essential amino acid [11C-methyl] -L-methionine, to form a true biological amino acid tracer with external detectability. Carbon 24-30 interleukin 1 receptor like 1 Homo sapiens 38-52 6130090-4 1983 The extent of maximum stimulation of the EF-Tu GTPase in the presence of ribosomes varies moderately depending on the aa-tRNA species; a clear dependence on the nature of the aminoacyl side chain is observed in the effects of their respective C-C-A-aa fragments tested (C-C-A-Arg, C-C-A-Val, C-C-A-Phe, C-C-A-Met, C-C-A-Lys). Carbon 245-246 eukaryotic translation elongation factor 1 alpha 1 Homo sapiens 41-46 6132461-2 1983 Although alpha-hydroxylation is the most important process in the formation of mutagens, NO-HEX may be hydroxylated on the beta- and gamma-carbon atoms as well. Carbon 139-145 hematopoietically expressed homeobox Rattus norvegicus 92-95 71841-2 1977 The blockade of the reticuloendothelial system by carbon particle resulted in slightly shorter t1/2 values of AFP. Carbon 50-56 alpha-fetoprotein Rattus norvegicus 110-113 7153213-5 1982 The inactivated P-protein was associated with H-protein and the methylene carbon of glycine, but not the carboxyl carbon, in a manner not separable by gel filtration, although the molar ratios of those three components were not constant. Carbon 74-80 OCA2 melanosomal transmembrane protein Homo sapiens 16-25 953878-0 1976 Oyster citrate synthase: control of carbon entry into the Krebs cycle of a facultative anerobe. Carbon 36-42 citrate synthase Homo sapiens 7-23 7091020-6 1982 Concentrations of 20 to 22 carbon polyunsaturated fatty acids in the erythrocyte membrane phosphatidylethanolamine and phosphatidylcholine of SMA and Enfamil-fed infants were similar despite very significant differences in the amount of dietary 18 carbon precursor. Carbon 27-33 survival of motor neuron 1, telomeric Homo sapiens 142-145 1155143-5 1975 Insulin (0.1 U/ml) added in vitro stimulated glucose uptake, incorporation of glucose minus14-C into glycogen and incorporation of leucine minus14-C into protein in diabetic colon smooth muscle. Carbon 94-95 insulin Oryctolagus cuniculus 0-7 7056747-5 1982 13C NMR spectra of the modified ovalbumin show six well resolved resonances arising from the six carbons of the attached [U-13C]galactose. Carbon 97-104 ovalbumin Bos taurus 32-41 4571899-0 1973 Carbon source utilization tests as an aid to the classification of non-fermenting gram-negative bacteria. Carbon 0-6 activation induced cytidine deaminase Homo sapiens 38-41 6282258-1 1982 Rat liver ornithine aminotransferase is found to exchange the pro-S hydrogen on the delta-carbon atom of ornithine exclusively, thus showing that the mammalian enzyme transfers the delta-amino group and not the alpha-amino group as has been demonstrated with the plant enzyme [Mestichelli, Gupta & Spenser (1979) J. Biol. Carbon 90-96 ornithine aminotransferase Homo sapiens 10-36 11826889-2 1970 Fat is most efficient because it has a higher ratio of carbon and hydrogen to oxygen than do protein and carbohydrate, so stored food systems for long missions would logically rely heavily on this form of calories. Carbon 55-61 FAT atypical cadherin 1 Homo sapiens 0-3 6790577-9 1981 However, the H-protein from the patient could stimulate the P-protein catalyzed exchange of the carboxyl carbon of glycine with 14CO2, although the specific activity of the purified H-protein from the patient was only 4% of that of control human H-protein. Carbon 105-111 OCA2 melanosomal transmembrane protein Homo sapiens 60-69 4971602-5 1968 Thyroglobulin molecules dried in sodium tungstosilicate on a carbon film as for electron microscopy retained their hemagglutination-inhibiting activity and 19S sedimentation constant when redissolved in physiological buffer. Carbon 61-67 thyroglobulin Homo sapiens 0-13 7216425-7 1980 During growth in the yeast extract-supplemented medium, approximately 37% of the phosphoenolpyruvate carbon was converted to acetate by pyruvate kinase, a pyruvate-decarboxylating enzyme activity, and acetate kinase; the remaining 63% was converted to succinate via phosphoenolpyruvate carboxykinase, malate dehydrogenase, fumarate hydratase, and fumarate reductase. Carbon 101-107 fumarate reductase Saccharomyces cerevisiae S288C 347-365 31216141-6 1959 In calcite the carbon-oxygen symmetric stretching, mode v 1, becomes active at elevated pressures while the doubly degenerate v 3, stretching, and v 4, bending, frequencies split. Carbon 15-21 immunoglobulin kappa variable 1-5 Homo sapiens 56-59 7439930-3 1980 An experiments in mice with a range of human serum albumin (HSA) molecules acylated to various degrees with side-chains of 6--20 carbon atoms, the greatest antibody responses against HSA were induced by highly acylated HSA with side-chains of intermediate length (C10--14). Carbon 129-135 albumin Mus musculus 45-58 7396823-6 1980 Retention of 3H in the 6 alpha-position of the isolated 6 beta-hydroxyandrost-4-ene-3, 17-dione indicates that in the isomerase-catalysed migration of the C(5) = C(6) double bond, the incoming proton from the acidic group on the enzyme must enter C-6 from the beta-face, forcing the existing 3H into the 6 alpha-position. Carbon 155-156 complement C6 Homo sapiens 247-250 6987054-6 1980 Moreover, FCCP also inhibited ppGpp degradation in a ATPase-deficient strain growing on glucose as carbon source while, as expected, it did not change the level of ATP. Carbon 99-105 ATPase Escherichia coli 53-56 383580-5 1979 The yeast DNA fragment is 4700 base pairs long, and enables the host E. coli K-12 strain to grow in minimal medium containing galactose as the sole carbon source with a generation time of 14.3 h. The yeast galactokinase activity in the bacterial extracts is 0.7% of the bacterial galactokinase activity found in wild-type E. coli fully induced with fucose. Carbon 148-154 galactokinase Saccharomyces cerevisiae S288C 206-219 383580-5 1979 The yeast DNA fragment is 4700 base pairs long, and enables the host E. coli K-12 strain to grow in minimal medium containing galactose as the sole carbon source with a generation time of 14.3 h. The yeast galactokinase activity in the bacterial extracts is 0.7% of the bacterial galactokinase activity found in wild-type E. coli fully induced with fucose. Carbon 148-154 galactokinase Saccharomyces cerevisiae S288C 280-293 16345343-2 1979 An approach for approximating the carbon-bound electron composition of microbial cells from CHN data is also presented. Carbon 34-40 chimerin 1 Homo sapiens 92-95 681358-10 1978 The products of the model reaction and the covalently bound FAD of lipoamide dehydrogenase appear to be the result of a nucleophilic attack on the carbon at position 8 of the flavin ring by a thiolate anion, displacing the chloride. Carbon 147-153 dihydrolipoamide dehydrogenase Homo sapiens 67-90 213272-6 1978 The effects of phosphomonoester groups on base and sugar carbon resonances have been examined and it is noted that these groups cause downfield shifts for C-8 of all cyclonucleotides. Carbon 57-63 homeobox C8 Homo sapiens 155-158 205871-2 1978 The specific activities of galactokinase in Tetrahymena cells grown in defined media with galactose or glycerol as the principal carbon source are equivalent; the specific activity in glucose minimal medium is [unk] the value. Carbon 129-135 galactokinase 1 Homo sapiens 27-40 407361-4 1977 Plots of log Cth against the number of carbon atoms, n, in n-alcohols, n-aldehydes and n-fatty acids showed linear relationships as represented by long Cth=-An+B. Carbon 39-45 V-set and immunoglobulin domain containing 2 Homo sapiens 13-16 407361-4 1977 Plots of log Cth against the number of carbon atoms, n, in n-alcohols, n-aldehydes and n-fatty acids showed linear relationships as represented by long Cth=-An+B. Carbon 39-45 V-set and immunoglobulin domain containing 2 Homo sapiens 152-155 949342-3 1976 (-)-Hydroxycitrate, an inhibitor of ATP citrate lyase, markedly inhibited the incorporation of carbon from labelled glucose and 3-hydroxybutyrate into cerebral lipids, but had no effect on the incorporation of labelled acetate and acetoacetate into brain lipids. Carbon 95-101 ATP citrate lyase Rattus norvegicus 36-53 1277755-2 1976 Five-carbon-atom organic acids (C-5 acids) have been administered intravenously to rabbits with ventriculocisternal perfusion and continuous electroencephalographic recording (EEG). Carbon 5-11 complement C5 Oryctolagus cuniculus 32-35 958222-6 1976 The coordination bonds between C=O and magnesium atom in the longwave aggregate of bacterioviridin (750 nm) are observed without participation of the low-molecular addenda, The formation of the protochlorophyl 635 nm form and aggregated forms of magnesium-free pigments occurs without participation of carbonyl groups probably by direct interaction between the eta-electron systems of molecules. Carbon 31-32 endothelin receptor type A Homo sapiens 361-364 1194275-7 1975 From the frequency dependence of the paramagnetic contribution to the longitudinal relaxation rate (1/T1p) of the carbon 1 proton of alpha-D-xylose, the correlation time (tauc) which modulates the dipolar interaction between enzyme-bound Mn2+ and alpha-D-xylose has been determined (5.1 x 1o(-10) s). Carbon 114-120 interleukin 1 receptor like 1 Homo sapiens 102-105 170960-2 1975 The carbon-13 nuclear magnetic resonance (13C NMR) spectra of luteinizing hormone-releasing hormone (LH-RH) and lower homologous peptides have been assigned in aqueous solutions at various pH values. Carbon 4-10 gonadotropin releasing hormone 1 Homo sapiens 62-99 170960-2 1975 The carbon-13 nuclear magnetic resonance (13C NMR) spectra of luteinizing hormone-releasing hormone (LH-RH) and lower homologous peptides have been assigned in aqueous solutions at various pH values. Carbon 4-10 gonadotropin releasing hormone 1 Homo sapiens 101-106 241565-0 1975 Squid muscle citrate synthase: control of carbon entry into the Krebs cycle. Carbon 42-48 citrate synthase Homo sapiens 13-29 1159711-3 1975 [The C-17 position is the carbon attached to C-8 of the ergoline (1) skeleton as indicated in structure 2.] Carbon 26-32 homeobox C8 Homo sapiens 45-48 169239-5 1975 Numerous single carbon resonances are observed in the aromatic regions of 13C NMR spectra of cytochrome c, lysozyme, and myoglobin. Carbon 16-22 lysozyme Equus caballus 107-115 169240-7 1975 We present a summary of the chemical shift ranges for the various types of nonprotonated aromatic carbons of amino acid residues and hemes of diamagnetic proteins, based on our results for hen egg white lysozyme, horse heart ferrocytochrome c, horse carbon monoxide myoglobin, and carbon monoxide hemoglobins from various species... Carbon 98-105 lysozyme Equus caballus 203-211 5821035-0 1969 Effect of different carbon sources on the synthesis of lactate dehydrogenase in Mima polymorpha. Carbon 20-26 MTSS I-BAR domain containing 1 Homo sapiens 80-84 4386407-4 1968 Incorporation of either of these labelled carbon atoms into fatty acids would require a functioning citrate-cleavage pathway which consists of the enzymes ATP-citrate lyase, NAD-malate dehydrogenase and NADP-malate dehydrogenase. Carbon 42-48 ATP citrate lyase Rattus norvegicus 155-172 5917084-1 1966 Crystals of thyroglobulin have been obtained from ammonium sulfate solutions and have been examined by electron microscopy as shadowed carbon replicas. Carbon 135-141 thyroglobulin Homo sapiens 12-25 5943937-10 1966 1966.-Mima polymorpha, unable to grow in the presence of nonphosphorylated sugars as sole source of carbon and energy, grows rapidly and well in the presence of acetate, ethyl alcohol, short-chained fatty acids, and permeable intermediates of the tricarboxylic acid cycle. Carbon 100-106 MTSS I-BAR domain containing 1 Homo sapiens 6-10 20993975-0 1946 Fat metabolism and ketone body formation as shown by heavy carbon. Carbon 59-65 FAT atypical cadherin 1 Homo sapiens 0-3 16588517-0 1942 Radioactive Carbon as an Indicator of Carbon Dioxide Utilization: VIII. Carbon 12-18 cytochrome c oxidase subunit 8A Homo sapiens 66-70 33957451-0 2021 Development of the fluorescent carbon nanosensor for pH and temperature of liquid media with artificial neural networks. Carbon 31-37 phenylalanine hydroxylase Homo sapiens 53-55 33797604-0 2021 Determination of patulin using dual-dummy templates imprinted electrochemical sensor with PtPd decorated N-doped porous carbon for amplification. Carbon 120-126 protein tyrosine phosphatase receptor type D Homo sapiens 90-94 33797604-5 2021 The composite of PtPd decorated N-doped porous carbon has good conductivity and large surface area, and can amplify the signal. Carbon 47-53 protein tyrosine phosphatase receptor type D Homo sapiens 17-21 33372353-3 2021 Herein, we report a function-oriented strategy of deliberately constructing black phosphorus quantum dots-ZnIn 2 S 4 (BP/ZIS) heterostructures for solar-driven CO 2 reduction to syngas paired with selectively oxidative C-N bond formation in one redox cycle. Carbon 160-161 zinc finger RANBP2-type containing 2 Homo sapiens 121-124 33688893-3 2021 Herein, double-carbon confined cobalt germanium hydroxide (CGH@C/rGO) composites has been facilely synthesized with the supportion of l-ascorbic acid and graphene oxide (GO) as anode materials for sodium-ion storage. Carbon 15-21 hypertrichosis 2 (generalised, congenital) Homo sapiens 59-62 33688893-6 2021 Such outstanding electrochemical performance could be accredited to a strong interaction between CGH, carbon, and graphene, which increases the electronic conductivity, relieves the volume expansion aroused by sodiation/desodiation, shortens the pathway of electron/ion transportation that further improving the reaction kinetics and endowing the material with remarkable cycling capability. Carbon 102-108 hypertrichosis 2 (generalised, congenital) Homo sapiens 97-100 33600573-4 2021 We show in comparative viability and growth assays that yeast cells lacking MAK3/NAA30 grow poorly in non-fermentable carbon sources and other stress conditions. Carbon 118-124 peptide alpha-N-acetyltransferase MAK3 Saccharomyces cerevisiae S288C 76-80 33600573-4 2021 We show in comparative viability and growth assays that yeast cells lacking MAK3/NAA30 grow poorly in non-fermentable carbon sources and other stress conditions. Carbon 118-124 peptide alpha-N-acetyltransferase MAK3 Saccharomyces cerevisiae S288C 81-86 33576609-3 2021 ATF1 coding AATase was coexpressed in expression cassettes of ACS1/ACS2 and ALD6 to promote the carbon flux toward ethyl acetate from acetyl-CoA. Carbon 96-102 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 62-66 33576609-3 2021 ATF1 coding AATase was coexpressed in expression cassettes of ACS1/ACS2 and ALD6 to promote the carbon flux toward ethyl acetate from acetyl-CoA. Carbon 96-102 acetate--CoA ligase ACS2 Saccharomyces cerevisiae S288C 67-71 33576609-3 2021 ATF1 coding AATase was coexpressed in expression cassettes of ACS1/ACS2 and ALD6 to promote the carbon flux toward ethyl acetate from acetyl-CoA. Carbon 96-102 aldehyde dehydrogenase (NADP(+)) ALD6 Saccharomyces cerevisiae S288C 76-80 33586959-0 2021 Nucleolin-Targeted Ratiometric Fluorescent Carbon Dots with a Remarkably Large Emission Wavelength Shift for Precise Imaging of Cathepsin B in Living Cancer Cells. Carbon 43-49 nucleolin Homo sapiens 0-9 33668702-1 2021 Single-walled carbon nanotubes can induce mitochondrial F0F1-ATPase nanotoxicity through inhibition. Carbon 14-20 ATP synthase F1 subunit epsilon Homo sapiens 56-67 33668702-4 2021 In vitro studies suggest that inhibition responses in SMP of F0F1-ATPase enzyme were strongly dependent on the concentration assay (from 3 to 5 microg/mL) for both pristine and COOH single-walled carbon nanotubes types (SWCNT). Carbon 196-202 ATP synthase F1 subunit epsilon Homo sapiens 61-72 33672587-0 2021 Scavenger Receptor A1 Mediates the Uptake of Carboxylated and Pristine Multi-Walled Carbon Nanotubes Coated with Bovine Serum Albumin. Carbon 84-90 steroid receptor RNA activator 1 Cricetulus griseus 0-21 33669883-1 2021 This study deals with the preparation of activated carbon (CDSP) from date seed powder (DSP) by chemical activation to eliminate polyaromatic hydrocarbon-PAHs (naphthalene-C10H8) from synthetic wastewater. Carbon 51-57 solute carrier family 22 member 5 Homo sapiens 59-63 33669883-11 2021 CDSP showed a higher sorption performance than DSP due to its higher BET surface area and carbon content. Carbon 90-96 solute carrier family 22 member 5 Homo sapiens 0-4 33443520-0 2021 Blue luminescent N,S-doped carbon dots encapsulated in red emissive Eu-MOF to form dually emissive composite for reversible anti-counterfeit ink. Carbon 27-33 lysine acetyltransferase 8 Homo sapiens 71-74 33557113-3 2021 Therefore, in the present study, we examined the effect of MIA induced by polyinosinic:polycytidylic acid (Poly I:C) on the CX3CL1-CX3CR1 and CD200-CD200R axes, microglial trajectory (MhcII, Cd40, iNos, Il-1beta, Tnf-alpha, Il-6, Arg1, Igf-1, Tgf-beta and Il-4), and schizophrenia-like behaviour in adult male offspring of Sprague-Dawley rats. Carbon 114-115 Cd200 molecule Rattus norvegicus 142-147 33412847-5 2021 The Dubinin-Ashtakov characteristic sorption energy (EDA, kJ mol-1) of 22 compounds on a thermoseries of bamboo chars correlates strongly with the DP/MAS-13C NMR-determined bridgehead aromatic carbon fraction (chib), which relates to the mean ring cluster size. Carbon 193-199 ectodysplasin A Homo sapiens 53-56 33542218-3 2021 In this study, we found that poly(I:C) + TAK1 inhibitor 5Z-7-oxozeaenol (P5) concurrently induces RDA and necroptosis in Abin-1-/-, but not in Abin-1+/+ mouse embryonic fibroblasts (MEFs). Carbon 36-38 TNFAIP3 interacting protein 1 Mus musculus 121-127 33542218-3 2021 In this study, we found that poly(I:C) + TAK1 inhibitor 5Z-7-oxozeaenol (P5) concurrently induces RDA and necroptosis in Abin-1-/-, but not in Abin-1+/+ mouse embryonic fibroblasts (MEFs). Carbon 36-38 TNFAIP3 interacting protein 1 Mus musculus 143-149 33548768-2 2021 A conventional thermoplastic, solid brace failed during a quasi-static loading study, informing the investigation and development of an experimental carbon composite brace, maximizing stiffness and proximity of shank and foot cylindrical shells to provide the required degree of control. Carbon 149-155 SH3 and multiple ankyrin repeat domains 2 Homo sapiens 211-216 33215508-12 2021 Meanwhile, overexpression of duck TLR3 significantly promoted the transcription of IFN-beta, IRF7, TRIF, Mx, STAT1 and STAT2 mRNA after stimulation with poly(I:C). Carbon 160-162 toll like receptor 3 Homo sapiens 34-38 31216141-7 1959 From the shift in frequency of v 1 with pressure the "compressibility", [(-1/Ro) (dR/dp)], of the C-O bond length, R, is calculated to be 2.8x10-7/atmosphere. Carbon 98-99 immunoglobulin kappa variable 1-5 Homo sapiens 31-34 33984913-4 2021 In the process, a hierarchical porous carbon (HPC) adsorbent with excellent adsorption property for Cr(VI) and rhodamine B (RhB), was prepared from CG by a two-step method and characterized by SEM, TEM, XRD, XPS, TPD and BET. Carbon 38-44 delta/notch like EGF repeat containing Homo sapiens 221-224 33497733-7 2021 In ALV-J and poly(I:C) stimulated CEFs cells, the expression level of STAT1, IFN-alpha, IFN-beta, TLR3 and TLR7 were increased after IRF7 overexpressed, while the results were just the opposite after IRF7 interfered, which indicating that IRF7 may be associated with Toll-like receptor signaling pathway and JAK-STAT signaling pathway. Carbon 20-22 toll like receptor 3 Homo sapiens 98-102 33368711-5 2021 As for the spent catalysts, linear correlation of paramagnetic species concentration with the content of carbon deposits (determined by TGA/DTA) was found. Carbon 105-111 T-box transcription factor 1 Homo sapiens 136-139 33529448-5 2021 The HF offspring also displayed a disruption of lipid homeostasis associated with an altered methionine cycle and abnormal one-carbon metabolism that caused DNA hypermethylation and L-carnitine depletion associated with deactivated AMPK signaling and decreased expression of PPAR-alpha and genes for fatty acid oxidation. Carbon 127-133 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 232-236 33345971-5 2021 By employing iso-propanol as solvent and H-donor, and palladium nanoparticles immobilized on nitrogen-doped carbon (Pd/CNX) as efficient multifunctional catalyst, veratryl alcohol dehydroxylation exhibited almost 100% conversion along with very high selectivity for 1,2-dimethoxy-benzene (46%) and 3,4-dimethoxytoluene (54%). Carbon 108-114 calnexin Homo sapiens 119-122 33502119-2 2021 Here engineering and characterization of a nanobiosensor of the mitotic kinase CDK1, through multifunctionalization of carbon nanotubes with a CDK1-specific fluorescent peptide reporter, are described. Carbon 119-125 cyclin-dependent kinase 1 Mus musculus 79-83 33502119-2 2021 Here engineering and characterization of a nanobiosensor of the mitotic kinase CDK1, through multifunctionalization of carbon nanotubes with a CDK1-specific fluorescent peptide reporter, are described. Carbon 119-125 cyclin-dependent kinase 1 Mus musculus 143-147 33838464-0 2021 Three-dimensional heterogeneity analysis of climate aid"s carbon reduction effect. Carbon 58-64 activation induced cytidine deaminase Homo sapiens 52-55 33509226-7 2021 Metabolomics microarray analysis and transcriptome sequencing analysis revealed that GOLPH3L promotes central carbon metabolism in breast cancer by stabilizing the p53 suppressor SERPINE1. Carbon 110-116 golgi phosphoprotein 3 like Homo sapiens 85-92 33736179-7 2021 From 1985 to 2018, TAF-DOC estimated DOC loading from terrestrial to aquatic ecosystems in the conterminous United States to be 33.5 +- 2.2 TgC per year, which was roughly 0.39-0.49% of total soil organic carbon stock estimates. Carbon 205-211 TATA-box binding protein associated factor 8 Homo sapiens 19-22 33838464-2 2021 A body of related literature has estimated the impact of international climate aid on carbon emissions. Carbon 86-92 activation induced cytidine deaminase Homo sapiens 79-82 33325232-0 2021 Molecular Dynamics Simulations of the pH-Dependent Adsorption of Doxorubicin on Carbon Quantum Dots. Carbon 80-86 phenylalanine hydroxylase Homo sapiens 38-40 33838464-3 2021 However, these studies did not adequately consider the multi-dimensional heterogeneity of climate aid"s carbon reduction effect. Carbon 104-110 activation induced cytidine deaminase Homo sapiens 98-101 33426319-9 2020 Microbial biomass carbon (MBC) values of the 0-15 cm soil depth were increased over CT by 18.57%, 47.08%, and 71.5% for CA3, CA6, and CA9 respectively. Carbon 18-24 carbonic anhydrase 6 Homo sapiens 125-128 33838464-4 2021 Based on national panel data of 77 recipients from 1980 to 2016, this study is the first to analyze the heterogeneous characteristics of climate aid"s carbon reduction effect from three dimensions of emission level, aid level, and income level. Carbon 151-157 activation induced cytidine deaminase Homo sapiens 145-148 33426319-9 2020 Microbial biomass carbon (MBC) values of the 0-15 cm soil depth were increased over CT by 18.57%, 47.08%, and 71.5% for CA3, CA6, and CA9 respectively. Carbon 18-24 carbonic anhydrase 9 Homo sapiens 134-137 33838464-4 2021 Based on national panel data of 77 recipients from 1980 to 2016, this study is the first to analyze the heterogeneous characteristics of climate aid"s carbon reduction effect from three dimensions of emission level, aid level, and income level. Carbon 151-157 activation induced cytidine deaminase Homo sapiens 216-219 34054147-2 2021 This article describes an electrochemical immunoassay platform developed to determine the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) spike antibody by using gold-clusters capped with cysteamine, glutaraldehyde, the spike protein of the SARS-CoV-2 antigen and bovine serum albumin on a glassy carbon electrode. Carbon 310-316 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 151-156 33838464-5 2021 Results show that, totally speaking, climate aid has a significant negative effect on carbon emissions in recipient countries. Carbon 86-92 activation induced cytidine deaminase Homo sapiens 45-48 33838464-7 2021 Meanwhile, climate aid also has significant negative effects on carbon emissions in recipient countries with high-aid level, i.e., only when the amount of aid reaches relatively high levels can climate aid play its role in reducing emissions. Carbon 64-70 activation induced cytidine deaminase Homo sapiens 19-22 33328306-5 2020 Gene edited PK-15 cell lines were used to show the dsRNA-sensing pathogen recognition receptors (PRRs) TLR3 and RIG-I specifically respond to poly(I:C) and SeV respectively, subsequently triggering apoptosis through pathways that converge on IRF3 and culminate in the cleavage of caspase-3. Carbon 149-150 DExD/H-box helicase 58 Sus scrofa 112-117 33838464-7 2021 Meanwhile, climate aid also has significant negative effects on carbon emissions in recipient countries with high-aid level, i.e., only when the amount of aid reaches relatively high levels can climate aid play its role in reducing emissions. Carbon 64-70 activation induced cytidine deaminase Homo sapiens 114-117 33838464-7 2021 Meanwhile, climate aid also has significant negative effects on carbon emissions in recipient countries with high-aid level, i.e., only when the amount of aid reaches relatively high levels can climate aid play its role in reducing emissions. Carbon 64-70 activation induced cytidine deaminase Homo sapiens 114-117 33321943-8 2020 As hCg-6 and hCg-42 produced a set of natural derivatives, the structure/activity relationship linked to the carbon tail is clarified. Carbon 109-115 ferric chelate reductase 1 like Homo sapiens 3-8 34029588-7 2021 Following this observation, a proteomic screen of the viperin interactome identified several cholesterol biosynthetic enzymes among the top hits, including lanosterol synthase (LS) and squalene monooxygenase (MS), which are enzymes that catalyze key steps in establishing the sterol carbon skeleton. Carbon 283-289 radical S-adenosyl methionine domain containing 2 Homo sapiens 54-61 34017059-6 2021 Here, we review our understanding of the roles of dietary carbohydrates (glucose, fructose, and fibers) and the gut microbiota, which provides essential carbon sources for hepatic fat synthesis during the development of NAFLD. Carbon 153-159 FAT atypical cadherin 1 Homo sapiens 180-183 34017601-3 2021 The relationship among fractal dimension, organic carbon content (TOC) and BET-specific surface area was analysed based on the fractal dimension of shale pores calculated using the Frenkel-Halsey-Hill model. Carbon 50-56 delta/notch like EGF repeat containing Homo sapiens 75-78 33781841-2 2021 This review discusses the complex activity of CYP17A1, looking at its role in both the classical and backdoor steroidogenic pathways and the complex chemistry it carries out to perform both a hydroxylation reaction and a carbon-carbon cleavage, or lyase reaction. Carbon 221-227 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 46-53 33781841-2 2021 This review discusses the complex activity of CYP17A1, looking at its role in both the classical and backdoor steroidogenic pathways and the complex chemistry it carries out to perform both a hydroxylation reaction and a carbon-carbon cleavage, or lyase reaction. Carbon 228-234 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 46-53 33984607-10 2021 Nonetheless, adding rmTim-3 Fc or rmGal-9 significantly down-regulated CXCR1 expression and IFN-gamma release in NK cells activated by poly I:C, proposing a means to exploit the Tim-3 pathway to reverse responses in NK cells. Carbon 71-72 hepatitis A virus cellular receptor 2 Mus musculus 22-27 33985221-1 2021 The particulate backscattering coefficient (bbp) provides effective proxies for particulate organic carbon (POC) and phytoplankton carbon (Cphy); however, their bio-optical relationships in the oligotrophic ocean are rarely reported. Carbon 100-106 transmembrane protein 158 Homo sapiens 44-47 33985221-1 2021 The particulate backscattering coefficient (bbp) provides effective proxies for particulate organic carbon (POC) and phytoplankton carbon (Cphy); however, their bio-optical relationships in the oligotrophic ocean are rarely reported. Carbon 131-137 transmembrane protein 158 Homo sapiens 44-47 33429261-0 2021 Bi2S3@Ag2S nano-heterojunction decorated self-floating carbon fiber cloth and enhanced solar-driven photothermal-photocatalytic performance. Carbon 55-61 angiotensin II receptor type 1 Homo sapiens 6-10 33713652-9 2021 We further detected a change in parasite central carbon metabolism, with lipB deletion resulting in changes to glycolysis and tricarboxylic acid cycle activity. Carbon 49-55 lipase B, lysosomal acid type Homo sapiens 73-77 33826352-3 2021 The reaction proceeds via C-S bond formation through EDA complex/thioester cleavage/inter-or intramolecular sulfa-Michael addition followed by aldol reaction sequence. Carbon 26-27 ectodysplasin A Homo sapiens 53-56 33863814-7 2021 Furthermore, ASNS overexpression led to modifications of the one-carbon metabolism to promote a more antioxidant tumor environment revealing a metabolic vulnerability that may be therapeutically exploited. Carbon 65-71 asparagine synthetase (glutamine-hydrolyzing) Homo sapiens 13-17 33418518-2 2021 In this work, a strategy for the construction of carbon-based catalysts was proposed with Magnoliaceae root biomass as a carbon source, doped by SnS2 and further decorated with heteropoly acid. Carbon 49-55 sodium voltage-gated channel alpha subunit 11 Homo sapiens 145-149 33418518-3 2021 The introduction of SnS2 can activate the carbon atom and destroy the electronic inertness of the disordered biochar with 002 planes. Carbon 42-48 sodium voltage-gated channel alpha subunit 11 Homo sapiens 20-24 33855812-0 2021 Pyridine grafted on SnO2-loaded carbon nanotubes acting as cocatalyst for highly efficient electroreduction of CO2. Carbon 32-38 strawberry notch homolog 1 Homo sapiens 20-23 33921475-5 2021 We found that co-culture of iDCs with differentially activated LAD2 MCs in serum-containing media significantly modulated polyinosinic:polycytidylic acid (poly I:C)-elicited DC maturation as determined through the surface expression of the maturation markers CD80, CD83, CD86, and human leukocyte antigen(HLA)-DR. Once iDCs were generated in serum-free conditions, they became refractory to the maturation with poly I:C, and the LAD2 MC modulatory potential was minimized. Carbon 30-31 CD80 molecule Homo sapiens 259-263 33921475-5 2021 We found that co-culture of iDCs with differentially activated LAD2 MCs in serum-containing media significantly modulated polyinosinic:polycytidylic acid (poly I:C)-elicited DC maturation as determined through the surface expression of the maturation markers CD80, CD83, CD86, and human leukocyte antigen(HLA)-DR. Once iDCs were generated in serum-free conditions, they became refractory to the maturation with poly I:C, and the LAD2 MC modulatory potential was minimized. Carbon 30-31 CD86 molecule Homo sapiens 271-275 33611192-6 2021 The molecular modeling illustrated that compound DC-K2in212 had the similar binding mode with CDK2 as C-73, the most selective CDK2 inhibitor reported so far, which might account for selectivity against CDK2 over CDK1. Carbon 50-51 cyclin dependent kinase 2 Homo sapiens 94-98 33611192-6 2021 The molecular modeling illustrated that compound DC-K2in212 had the similar binding mode with CDK2 as C-73, the most selective CDK2 inhibitor reported so far, which might account for selectivity against CDK2 over CDK1. Carbon 50-51 cyclin dependent kinase 2 Homo sapiens 127-131 33611192-6 2021 The molecular modeling illustrated that compound DC-K2in212 had the similar binding mode with CDK2 as C-73, the most selective CDK2 inhibitor reported so far, which might account for selectivity against CDK2 over CDK1. Carbon 50-51 cyclin dependent kinase 2 Homo sapiens 127-131 33797855-2 2021 Ucc1p of S. cerevisiae inhibits activation of the glyoxylate pathway by targeting Cit2p, a key glyoxylate enzyme for ubiquitin-mediated proteasomal degradation when glucose is available as a carbon source. Carbon 191-197 ubiquitin Saccharomyces cerevisiae S288C 117-126 33244811-4 2021 A key molecule is a core-crosslinked star-shaped polymer with multiple thermoresponsive arms, which can be prepared by reversible addition-fragmentation chain transfer polymerization of divinyl crosslinker with poly(N-isopropylacrylamide) (PNIPAAm) macro-chain transfer agent and have a number of unreacted carbon-carbon double bonds in the core. Carbon 307-313 steroidogenic acute regulatory protein Homo sapiens 37-41 33244811-4 2021 A key molecule is a core-crosslinked star-shaped polymer with multiple thermoresponsive arms, which can be prepared by reversible addition-fragmentation chain transfer polymerization of divinyl crosslinker with poly(N-isopropylacrylamide) (PNIPAAm) macro-chain transfer agent and have a number of unreacted carbon-carbon double bonds in the core. Carbon 314-320 steroidogenic acute regulatory protein Homo sapiens 37-41 33860111-0 2021 STAT6-Dependent Exacerbation of House Dust Mite-Induced Allergic Airway Disease in Mice by Multi-Walled Carbon Nanotubes. Carbon 104-110 signal transducer and activator of transcription 6 Mus musculus 0-5 33843742-5 2021 The characterization of the microporous MgO/AC composite showed that the magnesium oxide nanoparticles were successfully coated on the AC and the BET specific surface area of AC and MgO/AC were 1,540 and 1,246 m2/g, respectively. Carbon 44-46 delta/notch like EGF repeat containing Homo sapiens 146-149 33476211-0 2021 The TIM22 complex mediates the import of Sideroflexins and is required for efficient mitochondrial one-carbon metabolism. Carbon 103-109 translocase of inner mitochondrial membrane 22 Homo sapiens 4-9 33453420-3 2021 Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that catalyzes the methylation of nicotinamide (NAM) using the universal methyl donor S-adenosyl methionine (SAM), directly linking one-carbon metabolism with a cell"s methylation balance and nicotinamide adenine dinucleotide (NAD+) levels. Carbon 198-204 nicotinamide N-methyltransferase Homo sapiens 0-32 33453420-3 2021 Nicotinamide N-methyltransferase (NNMT) is a metabolic enzyme that catalyzes the methylation of nicotinamide (NAM) using the universal methyl donor S-adenosyl methionine (SAM), directly linking one-carbon metabolism with a cell"s methylation balance and nicotinamide adenine dinucleotide (NAD+) levels. Carbon 198-204 nicotinamide N-methyltransferase Homo sapiens 34-38 33338789-6 2021 AhR activity was removed by DWTPs using granulated activated carbon (GAC) and artificial infiltration. Carbon 61-67 aryl hydrocarbon receptor Homo sapiens 0-3 33157543-5 2021 Due to the tolerance of the presealed void in the carbon shells of the primary hollow-structured Si/void@C nanoparticles, the prepared pomegranate-like Silicon-based anodes deliver a high reversible capacity of 1615 mAg-1 at 0.1C and long cycle life of 73.5% capacity retention at 2C after 500 cycles, as well as high coulombic efficiency of 99%. Carbon 50-56 dentin matrix protein 1 Mus musculus 216-221 33708788-7 2021 Regarding the Kyoto Encyclopedia of Genes and Genomes colonic microbiota metabolic pathways, the CFD-fed HFA mice showed more similarities to the human donor than to the PFD-fed mice in amino sugar and nucleotide sugar metabolism, biosynthesis of amino acids, carbon metabolism, purine metabolism, and phosphotransferase systems. Carbon 260-266 complement factor D (adipsin) Mus musculus 97-100 33670002-6 2021 The average carbon density of forest ecosystems was 205.72 t hm-2, and the carbon storage of the forest ecosystems was 131.35 Tg (standard deviation: 31.01) inside study area. Carbon 12-18 cholinergic receptor muscarinic 2 Homo sapiens 61-65 33084099-0 2021 CoPd Nanoalloys with MOF as Template for Both N-doped Carbon and Cobalt Precursor: Efficient and Robust Catalysts for Hydrogenation Reactions. Carbon 54-60 COPD Homo sapiens 0-4 33084099-3 2021 Using ZIF-67 as template for both carbon matrix and cobalt precursor coating with a mesoporous SiO 2 layer, the catalyst CoPd/NC@SiO 2 were smoothly constructed. Carbon 34-40 COPD Homo sapiens 121-125 33303142-4 2021 In this study, the chitosan (CS) capped with gold nanoparticles (AuNPs) were self-assembled on a screen-printed carbon electrode (SPCE) and complete the elaboration of the molecularly imprinted polymer (MIP) sensor in the presence of BHA as templates. Carbon 112-118 citrate synthase Homo sapiens 29-31 33452755-9 2021 Moreover, they repressed poly(I:C)-induced phosphorylation of IFN regulatory factor (IRF) 3 and signal transducers and activators of transcription (STAT) 1, which is involved in Janus kinase (JAK)/STAT signaling. Carbon 32-34 interferon regulatory factor 3 Mus musculus 62-91 33203703-2 2021 Fatty acid 2-hydroxylase (FA2H) introduces a chiral hydroxyl group at the second carbon of FA backbones and influences lipid structures and metabolic signaling. Carbon 81-87 fatty acid 2-hydroxylase Homo sapiens 0-24 33203703-2 2021 Fatty acid 2-hydroxylase (FA2H) introduces a chiral hydroxyl group at the second carbon of FA backbones and influences lipid structures and metabolic signaling. Carbon 81-87 fatty acid 2-hydroxylase Homo sapiens 26-30 33451099-2 2021 A series of carbon-coated gamma-alumina pellets (C@Fe-Al2O3) were synthesized and characterized by TGA, Brunauer-Emmett-Teller (BET) method, Raman spectroscopy, SEM, TEM, and XPS in order to get comprehensive knowledge of their properties at the nanoscale and relate them with their catalytic behavior. Carbon 12-18 T-box transcription factor 1 Homo sapiens 99-102 33419117-4 2021 Under these conditions, the yield of activated carbon reached 27.4% with a BET surface area of 1420 m2 g-1, an average pore size of 2.1 nm, a total pore volume of 0.747 cm3 g-1, and a t-Plot micropore volume of 0.428 cm3 g-1. Carbon 47-53 delta/notch like EGF repeat containing Homo sapiens 75-78 33403765-4 2021 The results show that: (1) The alkyl polarizability effect index (PEI) has an important influence on the chemical shifts of the above four atoms, with the increase of PEI, the values of deltaH (CH=N) and deltac (CH=N) decrease, while the values of deltaH (OH) and deltaC (C-OH) increase. Carbon 194-195 chimerin 1 Homo sapiens 212-216 33401736-1 2021 Application of glass- or carbon-fiber-reinforced polymer (GFRP/CFRP) bars makes the direct use of seawater and sea sand concrete (SWSSC) in construction feasible, which is of high interest in order to conserve the limited resources of fresh water and river sand. Carbon 25-31 GTP cyclohydrolase I feedback regulator Homo sapiens 58-62 31872783-6 2021 We purposed a new mechanism that the protein context is primarily responsible for the atypical intramolecular SH3-fSBP recognition in c-Src kinase, which can promote the tight packing of segment against domain surface, support the segment polyproline-II (PPII) conformation in unbound state, and avoid unfavorable segment interactions with SH3 charged region by forming a C-terminal t-turn. Carbon 372-373 C-terminal Src kinase Homo sapiens 134-146 33531997-7 2021 Subsequent experiments demonstrated the significant upregulation of p-MLKL in the PR-NPC cells treated by carbon ion (4 Gy) compared with photon irradiation at both physical (4 Gy) and RBE (10 Gy) doses (P<=0.0001). Carbon 106-112 mixed lineage kinase domain like pseudokinase Homo sapiens 70-74 33531997-8 2021 Moreover, carbon ion induced a robust (up to 28 folds) p-MLKL in the PR-NPC cells as well as sensitive cells (up to 6-fold) coupled with a lower level of BCL-x expression and increased GM-CSF implicated in resculputure of immune system. Carbon 10-16 mixed lineage kinase domain like pseudokinase Homo sapiens 57-61 33445177-3 2021 Stimulation with Poly I:C up-regulated C3aR mRNA and intra- and extracellular expression in NHEKs which showed functional relevance by up-regulating CXCL10 and down-regulating C3 expression in response to C3a. Carbon 24-25 complement C3a receptor 1 Homo sapiens 39-43 33445177-4 2021 mRNA and protein levels of C3 and protease cathepsin L (CTSL) that can cleave C3 were up-regulated by the TLR3 ligand Poly I:C. Carbon 27-28 toll like receptor 3 Homo sapiens 106-110 33017609-5 2021 In line with the LogP and LogS values of the tested molecules, we found that TGF-beta-induced Smad-3 phosphorylation and cell migration were optimally inhibited, provided that the lateral aliphatic chain of the galloyl moiety reached 8 to 10 carbons. Carbon 242-249 transforming growth factor alpha Homo sapiens 77-85 33017609-5 2021 In line with the LogP and LogS values of the tested molecules, we found that TGF-beta-induced Smad-3 phosphorylation and cell migration were optimally inhibited, provided that the lateral aliphatic chain of the galloyl moiety reached 8 to 10 carbons. Carbon 242-249 SMAD family member 3 Homo sapiens 94-100 33335403-6 2020 The expression of some apoptotic and autophagy-related genes such as Bax, Bcl2, Beclin1 and ATG7 was significantly induced by carbon-ion beam irradiation alone and was further enhanced when the beam was combined with 5-FU. Carbon 126-132 autophagy related 7 Homo sapiens 92-96 33335403-7 2020 The spheroid forming capacity of CD133+ cell subpopulations was significantly inhibited by carbon-ion beam in combination with 5-FU. Carbon 91-97 prominin 1 Homo sapiens 33-38 33211784-3 2020 This study focuses on characterizing the catalyzed isomerization and adduct formation pathways for the reaction between formic acid and methyl vinyl ketone oxide (MVK-oxide), a four-carbon unsaturated Criegee intermediate generated from isoprene ozonolysis. Carbon 182-188 mevalonate kinase Homo sapiens 163-166 32157940-4 2020 Moreover, ACBP/DBI neutralization results into enhanced triglyceride lipolysis in white fat, a surge in free fatty acids in the plasma, enhanced incorporation of glycerol-derived carbon atoms into glucose, as well as an increase in beta-oxidation, resulting in a net reduction of fat mass. Carbon 179-185 diazepam binding inhibitor Mus musculus 10-14 32157940-4 2020 Moreover, ACBP/DBI neutralization results into enhanced triglyceride lipolysis in white fat, a surge in free fatty acids in the plasma, enhanced incorporation of glycerol-derived carbon atoms into glucose, as well as an increase in beta-oxidation, resulting in a net reduction of fat mass. Carbon 179-185 diazepam binding inhibitor Mus musculus 15-18 32997972-2 2020 The cholesterol within Lp(a) (Lp(a)-C) contributes to the reported LDL-cholesterol (LDL-C) concentration by nearly all available methods. Carbon 35-37 lipoprotein(a) Homo sapiens 23-28 33254626-7 2020 However, Nano-Ni-C did not cause these effects, suggesting surface modification of Nano-Ni, such as carbon coating, alleviates Nano-Ni-induced miR-21 and MMPs upregulation. Carbon 100-106 microRNA 21a Mus musculus 143-149 32543018-0 2020 Tunable multi-color S/N co-doped carbon quantum dots synthesized from wasted foam and application to detection of Cr3+ ions. Carbon 33-39 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 114-117 33596473-6 2020 In screening assays focused on the conversion of prodrug to TRE, TP (16 carbon alkyl chain) had the slowest rate of conversion compared with short-alkyl chain TRE prodrugs (i.e., 2-8 carbon alkyl chain). Carbon 72-78 thymidine phosphorylase Rattus norvegicus 65-67 33596473-6 2020 In screening assays focused on the conversion of prodrug to TRE, TP (16 carbon alkyl chain) had the slowest rate of conversion compared with short-alkyl chain TRE prodrugs (i.e., 2-8 carbon alkyl chain). Carbon 183-189 thymidine phosphorylase Rattus norvegicus 65-67 33260706-1 2020 Activated carbon (AC) with a very high surface area of over 2000 m2/g was produced from low sulfur acid hydrotropic lignin (AHL) from poplar wood using H3PO4 at a moderate temperature of 450 C (AHL-AC6). Carbon 10-16 adenylate cyclase 6 Homo sapiens 199-202 33179677-7 2020 The interaction of BIIICl(SubPc2-) with three equivalents of CN- is accompanied by the addition of two CN- to carbon atoms of SubPc2- closest to meso-nitrogen atoms forming {BIII(CN)[SubPc(CN)2]4-}2-. Carbon 110-116 calcium voltage-gated channel subunit alpha1 B Homo sapiens 19-23 32846294-7 2020 This esterase was also able to transform p-nitrophenyl esters (C4-C8), and the activity decreased when the carbon chain length increased. Carbon 107-113 alpha/beta hydrolase Thermotoga maritima MSB8 5-13 32897613-0 2020 MOF-Mediated Fabrication of Porous 3-D Superstructure of Carbon Nanosheets Decorated with Ultrafine Cobalt Phosphide Nanoparticles for Efficient Electrocatalysis. Carbon 57-63 lysine acetyltransferase 8 Homo sapiens 0-3 33057484-4 2020 Further computational results rationalize that the high regioselectivity is a consequence of the localization of high spin density and large frontier molecular orbital distribution on the corresponding carbon atoms stemming from the encapsulation of an yttrium atom into the low-symmetry Cs(6)-C82 cage with three-electron transfer from the metal to the cage. Carbon 202-208 complement C8 beta chain Homo sapiens 294-297 33156304-2 2020 Herein, a unique stable structure is developed, where the SnS2 nanocrystals (NCs) are sturdily encapsulated by carbon shells anchored on a reduced graphene oxide (rGO) via the one-pot solvothermal process. Carbon 111-117 sodium voltage-gated channel alpha subunit 11 Homo sapiens 58-62 33156304-3 2020 The well-controlled carbon shells provide the enduring protection for SnS2 NCs through C-S covalent bonds from the corrosion of electrolyte and pulverization of structure. Carbon 20-26 sodium voltage-gated channel alpha subunit 11 Homo sapiens 70-74 32599245-7 2020 We have identified significant interaction between ISGs and TLR3 agonists, like poly I: C, and imiquimod, and suggests that TLR3 agonists can be considered as a potential drug for drug repurposing in COVID-19. Carbon 88-89 toll like receptor 3 Homo sapiens 60-64 32599245-7 2020 We have identified significant interaction between ISGs and TLR3 agonists, like poly I: C, and imiquimod, and suggests that TLR3 agonists can be considered as a potential drug for drug repurposing in COVID-19. Carbon 88-89 toll like receptor 3 Homo sapiens 124-128 33172168-0 2020 Key Factors Influencing Low-Carbon Behaviors of Staff in Star-Rated Hotels-An Empirical Study of Eastern China. Carbon 28-34 steroidogenic acute regulatory protein Homo sapiens 57-61 33172168-3 2020 Therefore, this research aims to examine the effect of influencing factors inside and outside of the hotel context on hotel staff"s low-carbon behaviors in star-rated hotels. Carbon 136-142 steroidogenic acute regulatory protein Homo sapiens 156-160 33172168-6 2020 The results revealed that low-carbon managerial activities, strategic orientation, social norms, and perceived behavior control were four key factors affecting the low-carbon behavior adoption of staff from star-rated hotels. Carbon 30-36 steroidogenic acute regulatory protein Homo sapiens 207-211 33172168-6 2020 The results revealed that low-carbon managerial activities, strategic orientation, social norms, and perceived behavior control were four key factors affecting the low-carbon behavior adoption of staff from star-rated hotels. Carbon 168-174 steroidogenic acute regulatory protein Homo sapiens 207-211 33103172-3 2020 Therefore, we aim to construct a functionalized single-walled carbon nanotube (F-CNT) bound to siRNA from Caspase3. Carbon 62-68 caspase 3 Rattus norvegicus 106-114 33139765-3 2020 The hybrid carbon TIM exhibited maximum thermal conductivity when the SWCNT content was near 10 wt%. Carbon 11-17 Rho guanine nucleotide exchange factor 5 Homo sapiens 18-21 33139765-8 2020 This work provides a simple and effective pathway towards a carbon-based TIM that can be applied to a high temperature TEG. Carbon 60-66 Rho guanine nucleotide exchange factor 5 Homo sapiens 73-76 32871382-3 2020 Here we analyzed 66 soil microbial communities from five FACE sites, and showed common microbial response patterns to eCO2, especially for key functional genes involved in carbon and nitrogen fixation (e.g., pcc/acc for carbon fixation, nifH for nitrogen fixation), carbon decomposition (e.g., amyA and pulA for labile carbon decomposition, mnp and lcc for recalcitrant carbon decomposition), and greenhouse gas emissions (e.g., mcrA for methane production, norB for nitrous oxide production) across five FACE sites. Carbon 220-226 crystallin gamma D Homo sapiens 208-211 32871382-3 2020 Here we analyzed 66 soil microbial communities from five FACE sites, and showed common microbial response patterns to eCO2, especially for key functional genes involved in carbon and nitrogen fixation (e.g., pcc/acc for carbon fixation, nifH for nitrogen fixation), carbon decomposition (e.g., amyA and pulA for labile carbon decomposition, mnp and lcc for recalcitrant carbon decomposition), and greenhouse gas emissions (e.g., mcrA for methane production, norB for nitrous oxide production) across five FACE sites. Carbon 220-226 crystallin gamma D Homo sapiens 208-211 32871382-3 2020 Here we analyzed 66 soil microbial communities from five FACE sites, and showed common microbial response patterns to eCO2, especially for key functional genes involved in carbon and nitrogen fixation (e.g., pcc/acc for carbon fixation, nifH for nitrogen fixation), carbon decomposition (e.g., amyA and pulA for labile carbon decomposition, mnp and lcc for recalcitrant carbon decomposition), and greenhouse gas emissions (e.g., mcrA for methane production, norB for nitrous oxide production) across five FACE sites. Carbon 220-226 crystallin gamma D Homo sapiens 208-211 32871382-3 2020 Here we analyzed 66 soil microbial communities from five FACE sites, and showed common microbial response patterns to eCO2, especially for key functional genes involved in carbon and nitrogen fixation (e.g., pcc/acc for carbon fixation, nifH for nitrogen fixation), carbon decomposition (e.g., amyA and pulA for labile carbon decomposition, mnp and lcc for recalcitrant carbon decomposition), and greenhouse gas emissions (e.g., mcrA for methane production, norB for nitrous oxide production) across five FACE sites. Carbon 220-226 crystallin gamma D Homo sapiens 208-211 32871382-6 2020 A conceptual framework was developed to link commonly responsive functional genes with ecosystem processes, such as pcc/acc vs. soil carbon storage, amyA/pulA/mnp/lcc vs. soil carbon decomposition, and nifH vs. nitrogen availability, suggesting that such common responses of microbial functional genes may have the potential to predict ecosystem functioning and sustainability in the future eCO2 environment. Carbon 133-139 crystallin gamma D Homo sapiens 116-119 32888606-7 2020 The transcript levels of most genes related to photosystem II (PSII), cytochrome b6/f (Cytb6f), photosystem I (PSI) and carbon fixation were upregulated, revealing one important regulatory circuit for the maintenance of chloroplast homeostasis under SO2 stress. Carbon 120-126 cytochrome b6 Arabidopsis thaliana 70-85 32574913-5 2020 The as-prepared composite of carbon fibers and FeNi alloy nanoparticles exhibited a small overpotential of 317 mV at 10 mA cm-2 and low Tafel slope of 49 mV dec-1 for oxygen evolution reaction, as well as good stability. Carbon 29-35 deleted in esophageal cancer 1 Homo sapiens 157-162 32931247-0 2020 Non-Innocent Role of Porous Carbon Towards Enhancing C2-3 Products in Electroreduction of Carbon Dioxide. Carbon 28-34 nucleolin Homo sapiens 53-57 33050324-7 2020 Furthermore, activation of IRF3 by polyinosinic-polycytidylic acid (poly I:C) produced a cooperative effect with TNF-alpha for MIP-1alpha/CCL3 production that was comparable to stearic acid. Carbon 75-76 interferon regulatory factor 3 Homo sapiens 27-31 32583114-10 2020 The main elements available on the surface of HFe included carbon, oxygen, iron, calcium, magnesium, silicon, platinum, sulphur, manganese, titanium and aluminium. Carbon 59-65 homeostatic iron regulator Homo sapiens 46-49 32384980-0 2020 Synthesis of Multi-Color Fluorescent Carbon Dots From Mint Leaves: A Robust Bioimaging Agent with Potential Antioxidant Activity. Carbon 37-43 spen family transcriptional repressor Homo sapiens 54-58 32599138-12 2020 By comparing the transcriptomes of CC4348 and gpx5 mutant, we found that both CC4348 and gpx5 mutant cells displayed upregulation of transcripts related to protein, nucleic acid, carbon metabolism and chlorophyll biosynthesis, but more proportion of genes related to lipid metabolism were up-regulated in CC4348 than that in the gpx5 mutant. Carbon 179-185 uncharacterized protein Chlamydomonas reinhardtii 46-50 32599138-12 2020 By comparing the transcriptomes of CC4348 and gpx5 mutant, we found that both CC4348 and gpx5 mutant cells displayed upregulation of transcripts related to protein, nucleic acid, carbon metabolism and chlorophyll biosynthesis, but more proportion of genes related to lipid metabolism were up-regulated in CC4348 than that in the gpx5 mutant. Carbon 179-185 uncharacterized protein Chlamydomonas reinhardtii 89-93 32599138-12 2020 By comparing the transcriptomes of CC4348 and gpx5 mutant, we found that both CC4348 and gpx5 mutant cells displayed upregulation of transcripts related to protein, nucleic acid, carbon metabolism and chlorophyll biosynthesis, but more proportion of genes related to lipid metabolism were up-regulated in CC4348 than that in the gpx5 mutant. Carbon 179-185 uncharacterized protein Chlamydomonas reinhardtii 89-93 33072094-5 2020 We also observed elevated MMP12 in our multiwall carbon nanotube (MWCNT) murine model of granulomatous inflammation. Carbon 49-55 matrix metallopeptidase 12 Mus musculus 26-31 32914377-0 2020 Molecularly Imprinted Polymers Doped with Carbon Nanotube with Aid of Metal-Organic Gel for Drug Delivery Systems. Carbon 42-48 activation induced cytidine deaminase Homo sapiens 63-66 32914377-4 2020 Our goal was to develop a molecularly imprinted polymer (MIP) based delivery system to control the release of AG and demonstrate the availability of this drug delivery system (DDS), which was doped with carbon nanotube with aid of metal-organic gel. Carbon 203-209 activation induced cytidine deaminase Homo sapiens 224-227 32621945-3 2020 Reasoning that MyD88 inhibition in a virus-like manner may increase type I IFN responses, our studies revealed lipopolysaccharide stimulation of U937 cells or poly I:C stimulation of HEK293-TLR3, THP1 or U87 cells in the presence of a previously reported MyD88 inhibitor (compound 4210) augmented IFN-beta and RANTES production. Carbon 166-167 MYD88 innate immune signal transduction adaptor Homo sapiens 15-20 32621945-3 2020 Reasoning that MyD88 inhibition in a virus-like manner may increase type I IFN responses, our studies revealed lipopolysaccharide stimulation of U937 cells or poly I:C stimulation of HEK293-TLR3, THP1 or U87 cells in the presence of a previously reported MyD88 inhibitor (compound 4210) augmented IFN-beta and RANTES production. Carbon 166-167 toll like receptor 3 Homo sapiens 190-194 32824595-3 2020 Of the various TLR ligands examined, the TLR3-specific ligand polyinosinic:polycytidylic acid (poly I:C), significantly induced TNF production and the upregulation of other TLR transcripts, in particular, TLR2. Carbon 102-103 toll-like receptor 2 Mus musculus 15-18 32824595-3 2020 Of the various TLR ligands examined, the TLR3-specific ligand polyinosinic:polycytidylic acid (poly I:C), significantly induced TNF production and the upregulation of other TLR transcripts, in particular, TLR2. Carbon 102-103 toll-like receptor 2 Mus musculus 41-44 32824595-3 2020 Of the various TLR ligands examined, the TLR3-specific ligand polyinosinic:polycytidylic acid (poly I:C), significantly induced TNF production and the upregulation of other TLR transcripts, in particular, TLR2. Carbon 102-103 toll-like receptor 2 Mus musculus 205-209 32806538-1 2020 A nanocomposite comprising Ag nanoparticles on AgCl/Ag2S nanoparticles was decorated on multi-walled carbon nanotubes and used to modify a glassy carbon electrode. Carbon 101-107 angiotensin II receptor type 1 Homo sapiens 52-56 32806538-1 2020 A nanocomposite comprising Ag nanoparticles on AgCl/Ag2S nanoparticles was decorated on multi-walled carbon nanotubes and used to modify a glassy carbon electrode. Carbon 146-152 angiotensin II receptor type 1 Homo sapiens 52-56 32632426-5 2020 The coefficient of thermal expansion (CTE) and thermal distortion parameter (TDP) substantially decreased from 59.3 ppm C-1 and 17.5 m K-1 of EPDM/AlN, to 39.7 ppm C-1 and 8.4 m K-1 of EPDM/AlN/BN, representing reductions of 33 and 52%, respectively. Carbon 38-39 keratin 1 Homo sapiens 136-139 32627357-0 2020 Glucose uptake to guard cells via STP transporters provides carbon sources for stomatal opening and plant growth. Carbon 60-66 sulfotransferase family 1A member 1 Homo sapiens 34-37 32639727-4 2020 In both adipogenesis and transcriptional activity assays with human and mouse cells, PPARgamma activity of 7 PFCAs first increased and then decreased with their carbon chain length. Carbon 161-167 peroxisome proliferator activated receptor gamma Mus musculus 85-94 32746720-7 2021 Based on the asymmetry in both the dynamics behavior and the accumulated alpha carbon (Calpha) importance, we further suggested a relation among chains in the trimer spike protein, which leads to a deeper understanding on protein motions of the S1 subunit. Carbon 79-85 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 166-171 32775745-3 2020 FTIR spectra shows compound functional groups of hydroxyl (- OH) at peak 1 (3449.92 cm-1), carboxyl (-COOH) at peak 2 (1719.42 cm-1) and peak 3 (1702.62 cm-1), and alcohol (C-OH) at peak 4 (1628.12 cm-1) and epoxy (CO) at peak 5 (1158.51 cm-1), which is similar to the GO synthesis from pure graphite. Carbon 102-103 PEAK1 related, kinase-activating pseudokinase 1 Homo sapiens 111-117 32905515-6 2020 Carbon-ion beam combined with lapatinib significantly enhanced apoptosis and carbon-ion beam alone dose-dependently increased autophagy-related expression of Beclin1 and in combination with lapatinib greatly enhanced ATG7 expression at protein levels. Carbon 0-6 autophagy related 7 Homo sapiens 217-221 32628440-2 2020 In this study, Co-MOF nanorods (NRs) were prepared at room temperature, followed by calcination and hydrothermal sulfurization strategy to transform the MOF into CoS NRs on carbon cloth (CoS/CC). Carbon 173-179 lysine acetyltransferase 8 Homo sapiens 18-21 32628440-2 2020 In this study, Co-MOF nanorods (NRs) were prepared at room temperature, followed by calcination and hydrothermal sulfurization strategy to transform the MOF into CoS NRs on carbon cloth (CoS/CC). Carbon 173-179 lysine acetyltransferase 8 Homo sapiens 153-156 32874645-0 2020 A ratiometric fluorescent probe for pH detection based on Ag2S quantum dots-carbon dots nanohybrids. Carbon 76-82 angiotensin II receptor type 1 Homo sapiens 58-62 32614006-2 2020 The Mn-MOF was assembled with 2D black phosphorous nanosheets (BPNSs) to achieve novel 2D/3D BPNSs/Mn-MOF nanocomposites, followed by the direct coupling of methylene blue (MB)-labeled DNA aptamer on the interface of the nanocomposites-modified glassy carbon electrode (GCE). Carbon 252-258 lysine acetyltransferase 8 Homo sapiens 7-10 32617544-1 2020 Porous carbon microtubule (PCMT)-scaffolding semiconductor heterostructures were exquisitely designed through the in situ growth of ZnIn2S4 (ZIS) ultrathin nanosheets onto In2O3 nanoparticle layers generated on the surface PCMT (abbreviated as PCMT@In2O3/ZIS) toward the efficient photocatalytic conversion of CO2 into CO. Carbon 7-13 isoprenylcysteine carboxyl methyltransferase Homo sapiens 27-31 32617544-1 2020 Porous carbon microtubule (PCMT)-scaffolding semiconductor heterostructures were exquisitely designed through the in situ growth of ZnIn2S4 (ZIS) ultrathin nanosheets onto In2O3 nanoparticle layers generated on the surface PCMT (abbreviated as PCMT@In2O3/ZIS) toward the efficient photocatalytic conversion of CO2 into CO. Carbon 7-13 isoprenylcysteine carboxyl methyltransferase Homo sapiens 223-227 32617544-1 2020 Porous carbon microtubule (PCMT)-scaffolding semiconductor heterostructures were exquisitely designed through the in situ growth of ZnIn2S4 (ZIS) ultrathin nanosheets onto In2O3 nanoparticle layers generated on the surface PCMT (abbreviated as PCMT@In2O3/ZIS) toward the efficient photocatalytic conversion of CO2 into CO. Carbon 7-13 isoprenylcysteine carboxyl methyltransferase Homo sapiens 223-227 32617544-4 2020 (3) The existence of a large amount of carbon defects in PCMT promotes the activity of the absorbed CO2 molecules. Carbon 39-45 isoprenylcysteine carboxyl methyltransferase Homo sapiens 57-61 32644783-0 2020 Mechanical Insights into the Enzymatic Cleavage of Double C-C Bond in Poly(cis-1,4-isoprene) by the Latex Clearing Protein. Carbon 39-40 kelch domain containing 2 Homo sapiens 100-122 32644783-0 2020 Mechanical Insights into the Enzymatic Cleavage of Double C-C Bond in Poly(cis-1,4-isoprene) by the Latex Clearing Protein. Carbon 58-59 kelch domain containing 2 Homo sapiens 100-122 32681044-0 2020 Carbon nanotube porin diffusion in mixed composition supported lipid bilayers. Carbon 0-6 voltage dependent anion channel 1 Homo sapiens 16-21 32664606-0 2020 Linkage between Carbon Metabolism, Redox Status and Cellular Physiology in the Yeast Saccharomyces cerevisiae Devoid of SOD1 or SOD2 Gene. Carbon 16-22 superoxide dismutase SOD1 Saccharomyces cerevisiae S288C 120-124 32639961-4 2020 In the current study, we identify two understudied yeast genes, YTA6 and YPR096C that when deleted, cell sensitivity to LiCl is increased when galactose is used as a carbon source. Carbon 166-172 putative AAA family ATPase YTA6 Saccharomyces cerevisiae S288C 64-68 32452419-2 2020 Here, we demonstrated that the mutation of Aspartic acid 185 (Asp185) impaired the ability of nsp4 to inhibit IFN-I production induced by poly(I:C). Carbon 145-147 serine protease 57 Homo sapiens 94-98 31672636-2 2020 The hydrolytic activity of MelA alpha-galactosidase on a wide range of p-nitrophenyl glycoside derivatives and carbohydrates of different molecular-weights showed its high selectivity and efficiency towards the alpha(1 6) glycosidic bonds involving the anomeric carbon of galactose and the C6-hydroxyl group of galactose or glucose units. Carbon 262-268 alpha-galactosidase Lactobacillus plantarum WCFS1 27-31 32044638-6 2020 Conversion results demonstrated aromatics degraded easier than alkanes and more carbon atoms decreased difficulty, as CB~PhH > DCE~DCM, and DCE > DCM; but chlorinated substitution increased difficulty, as PhH > CB. Carbon 80-86 24-dehydrocholesterol reductase Homo sapiens 127-130 32420740-6 2020 The calculated results rationalize the experimentally observed enantio- and regioselectivities, and reveal that enantioselectivity of the reaction originates from the hydrogen bond interaction between TRIP and the N-H group of the carbon-centered radical, and the regioselectivity arises from the electron-withdrawing inductive effect from protonated N-atom and intramolecular hydrogen bond interaction between the acetylamino group and the protonated pyridine ring. Carbon 231-237 TRAF interacting protein Homo sapiens 201-205 32500058-2 2020 Two-dimensional (2D) metal oxides/hydroxides (TMOs/TMHs) are revolutionizing the design of high-performance supercapacitors because of their high theoretical specific capacitance, abundance of electrochemically active sites, and feasibility for assembly in hierarchical structures by integrating with graphitic carbon, conductive polymers, and so on. Carbon 311-317 LHFPL tetraspan subfamily member 5 Homo sapiens 51-55 32366814-7 2020 RESULTS ADSCs preconditioned with poly(I:C) showed the highest efficiency in inhibiting lymphocyte proliferation, which was correlated with the upregulation of fibrinogen-like protein 2 (FGL2), an effector molecule of Tregs. Carbon 41-43 fibrinogen-like protein 2 Mus musculus 160-185 32366814-7 2020 RESULTS ADSCs preconditioned with poly(I:C) showed the highest efficiency in inhibiting lymphocyte proliferation, which was correlated with the upregulation of fibrinogen-like protein 2 (FGL2), an effector molecule of Tregs. Carbon 41-43 fibrinogen-like protein 2 Mus musculus 187-191 31945721-1 2020 The present study estimated the concentration of black carbon (BC10 and BC2.5) during cooking hours in three types of kitchen in ten households and two improved cookstoves (ICS) tested against traditional mud cookstoves (TCS) in the real field conditions. Carbon 55-61 BLCAP apoptosis inducing factor Homo sapiens 63-67 32045605-6 2020 C-terminal part of the amino sequence of Slp2 protein was found to be highly similar to that of the conserved C-terminal region of SlpA protein of L. crispatus Zj001 isolated from pig intestines and CbsA protein of L. crispatus JCM5810 isolated from chicken intestines, and was substantially variable at the N-terminal and middle regions. Carbon 0-1 synaptotagmin like 2 Homo sapiens 41-45 32045605-6 2020 C-terminal part of the amino sequence of Slp2 protein was found to be highly similar to that of the conserved C-terminal region of SlpA protein of L. crispatus Zj001 isolated from pig intestines and CbsA protein of L. crispatus JCM5810 isolated from chicken intestines, and was substantially variable at the N-terminal and middle regions. Carbon 110-111 synaptotagmin like 2 Homo sapiens 41-45 32270832-2 2020 The dependence of the anisotropy on T/eta is shown to be described by the Perrin equation, which implies that Brownian rotational motion of carbon dots in solution is a basic mechanism of fluorescence depolarization. Carbon 140-146 endothelin receptor type A Homo sapiens 38-41 32354138-0 2020 rAAV-Mediated Overexpression of SOX9 and TGF-beta via Carbon Dot-Guided Vector Delivery Enhances the Biological Activities in Human Bone Marrow-Derived Mesenchymal Stromal Cells. Carbon 54-60 SRY-box transcription factor 9 Homo sapiens 32-36 32354138-0 2020 rAAV-Mediated Overexpression of SOX9 and TGF-beta via Carbon Dot-Guided Vector Delivery Enhances the Biological Activities in Human Bone Marrow-Derived Mesenchymal Stromal Cells. Carbon 54-60 transforming growth factor alpha Homo sapiens 41-49 32341997-5 2020 First, through the enrichment of deuterated glutamine in the polyQ sequence of mutant Huntingtin (mHtt) exon1 proteins for Huntington"s disease, we achieved sensitive and specific stimulated Raman scattering (SRS) imaging of carbon-deuterium bonds (C-D) from aggregates without GFP labeling, which is commonly employed in fluorescence microscopy. Carbon 225-231 huntingtin Homo sapiens 86-96 32182047-7 2020 Therefore, regardless of the amendment type, the addition of organic matter to soil increased the capability of the coarse fraction (FSa) to stabilize organic carbon, thus pointing out that the role of FSa in carbon sequestration in agricultural soils at a global scale may be overlooked. Carbon 159-165 bridge-like lipid transfer protein family member 1 Homo sapiens 133-136 32134147-3 2020 Here, we show that TGFbeta promotes protein translation at least in part by increasing the mitochondrial oxidation of glucose and glutamine carbons to support the bioenergetic demand of translation. Carbon 140-147 transforming growth factor alpha Homo sapiens 19-26 32134147-4 2020 Surprisingly, we found that in addition to stimulating the entry of glucose and glutamine carbon into the TCA cycle, TGFbeta induced the biosynthesis of proline from glutamine in a Smad4-dependent fashion. Carbon 90-96 transforming growth factor alpha Homo sapiens 117-124 32053770-6 2020 We further demonstrate that the C-terminal of caspase-8 is mainly responsible for the interaction with V-ATPase and can suffice to inhibit survival of cancer cells. Carbon 32-33 caspase 8 Homo sapiens 46-55 32141284-0 2020 Engineered pH-Responsive Mesoporous Carbon Nanoparticles for Drug Delivery. Carbon 36-42 phenylalanine hydroxylase Homo sapiens 11-13 33266406-3 2020 Most of SPL-1cut is carbon-about 65%-and its calorific value is 22.587 MJ kg-1. Carbon 20-26 sphingosine-1-phosphate lyase 1 Homo sapiens 8-13 33330321-0 2020 Carbon Ion Therapy Inhibits Esophageal Squamous Cell Carcinoma Metastasis by Upregulating STAT3 Through the JAK2/STAT3 Signaling Pathway. Carbon 0-6 Janus kinase 2 Homo sapiens 108-112 33330321-5 2020 Therefore, the aim of the present study was to investigate the relationship between carbon ion inhibition of the proliferation and metastasis of esophageal carcinoma cells and the JAK2/STAT3 signaling pathway. Carbon 84-90 Janus kinase 2 Homo sapiens 180-184 33330321-10 2020 Carbon ion beams also regulated CDH1 and MMP2 downstream of the STAT3 pathway and inhibited ESCC cell metastasis, which activated the STAT3 signaling pathway. Carbon 0-6 matrix metallopeptidase 2 Homo sapiens 41-45 33156304-3 2020 The well-controlled carbon shells provide the enduring protection for SnS2 NCs through C-S covalent bonds from the corrosion of electrolyte and pulverization of structure. Carbon 76-77 sodium voltage-gated channel alpha subunit 11 Homo sapiens 70-74 33176720-8 2020 Based on these DE-mRNAs, they were involved in biological processes such as fatty acid beta-oxidation, IRE1-mediated unfolded protein response, and transmembrane transport, and many KEGG pathways like glycine, serine and threonine metabolism, carbon metabolism. Carbon 243-249 endoplasmic reticulum to nucleus signaling 1 Homo sapiens 103-107 32640387-2 2020 Trihalomethanes (THMs) are one of the major classes of regulated disinfection byproducts, formed when a specific fraction of the organic carbon pool-referred to as THM precursors-reacts with chorine and/or bromine during treatment. Carbon 137-143 THM Homo sapiens 17-20 32049604-5 2020 Notably, increase in C/N ratio led to decrease in total ammonia nitrogen (TAN) and alkalinity concentration (Alk), hence, treatments with the lowest C/N ratio had better reactor performance in terms of suitable process parameters such as Alk, pH, ORP, and TAN. Carbon 21-22 phenylalanine hydroxylase Homo sapiens 243-245 32049604-5 2020 Notably, increase in C/N ratio led to decrease in total ammonia nitrogen (TAN) and alkalinity concentration (Alk), hence, treatments with the lowest C/N ratio had better reactor performance in terms of suitable process parameters such as Alk, pH, ORP, and TAN. Carbon 149-150 phenylalanine hydroxylase Homo sapiens 243-245 33838464-7 2021 Meanwhile, climate aid also has significant negative effects on carbon emissions in recipient countries with high-aid level, i.e., only when the amount of aid reaches relatively high levels can climate aid play its role in reducing emissions. Carbon 64-70 activation induced cytidine deaminase Homo sapiens 114-117 33652123-0 2021 Osteopontin mRNA expression by rat mesothelial cells exposed to multi-walled carbon nanotubes as a potential biomarker of chronic neoplastic transformation in vitro. Carbon 77-83 secreted phosphoprotein 1 Rattus norvegicus 0-11 32123882-5 2020 Consequently, as indicated by both XPS and ISS, the amount of adventitious carbon bound to HAp was higher than that on ACP or ACP HAp. Carbon 75-81 reticulon 3 Homo sapiens 91-94 32029103-0 2020 Carbon dots as fluorescent nanoprobe for the determination of N-acetyl-beta-d-glucosaminidase activity. Carbon 0-6 O-GlcNAcase Homo sapiens 62-93 32512434-6 2020 Evaluation of KSS data for the 4 h extractions showed that soil type and selected HMW-PAH properties (literature based molecular weight and octanol-carbon partition coefficients) affect the amount of HMW-PAH released from soil into sebum. Carbon 148-154 cilia and flagella associated protein 97 Homo sapiens 200-203 32650195-3 2020 We show that the synergistic effect of Fe, N, B in the mesoporous carbon structure can derive excellent ORR activity, for which the FeNB/C-800 catalyst delivers an onset potential of 0.97 V (vs. reversible hydrogen electrode, RHE), a half-wave potential of 0.81 V (vs. RHE) and a high limiting current density (5.59 mA cm-2), comparable to a commercial Pt/C. Carbon 66-72 factor interacting with PAPOLA and CPSF1 Homo sapiens 226-229 32650195-3 2020 We show that the synergistic effect of Fe, N, B in the mesoporous carbon structure can derive excellent ORR activity, for which the FeNB/C-800 catalyst delivers an onset potential of 0.97 V (vs. reversible hydrogen electrode, RHE), a half-wave potential of 0.81 V (vs. RHE) and a high limiting current density (5.59 mA cm-2), comparable to a commercial Pt/C. Carbon 66-72 factor interacting with PAPOLA and CPSF1 Homo sapiens 269-272 32029103-1 2020 Carbon dots (CDs) were synthesized from p-aminophenol and ethylenediamine via one-step under mild condition and used as a sensitive fluorescent nanoprobe for the activity determination of N-acetyl-beta-d-glucosaminidase (NAG). Carbon 0-6 O-GlcNAcase Homo sapiens 188-219 34029365-4 2021 show that like central carbon metabolism, iron metabolism is also closely implicated in autophagy-mediated life extension via the TORC2 activator Ypk1p and the iron regulator Aft1p. Carbon 23-29 serine/threonine protein kinase YPK1 Saccharomyces cerevisiae S288C 146-151 31914405-7 2020 Finally, we demonstrate that the C-terminal region of FOXN1 is required for high-affinity DNA binding and that FOXN1 has a significantly reduced affinity for DNA that contains 5"-methylcytosine, which may have implications for the role of FOXN1 in thymic involution. Carbon 33-34 forkhead box N1 Homo sapiens 54-59 33684425-10 2021 In addition, a separate group of animals neonatally treated with saline or Poly I:C from P5-7 demonstrated increased TNFalpha protein levels in the hippocampus but not prefrontal cortex, verifying increased TNFalpha in the brain produced by Poly I:C. Carbon 82-83 cyclin-dependent kinase inhibitor 1C Rattus norvegicus 89-93 32144607-1 2020 A carbon nanotube (CNT)-mediated antibody-free suspension array (CASA) by integration of functionalized CNTs and aptamer (Apt) into xMAP technology for simultaneous determination of typical endocrine-disrupting chemicals (EDCs) was developed . Carbon 2-8 casein alpha s1 Homo sapiens 65-69 33957045-3 2021 AoiQ represents the first biochemically reconstituted FDH that can halogenate an enolizable sp3-hybridized carbon atom. Carbon 107-113 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 54-57 32857208-0 2020 Radiosensitization of NSCLC cells to X-rays and carbon ions by the CHK1/CHK2 inhibitor AZD7762, Honokiol and Tunicamycin. Carbon 48-54 checkpoint kinase 2 Homo sapiens 72-76 33968889-9 2021 Both X-rays and Carbon ions promoted the exposure of HMGB1, IL-10, and TGF-beta in a time-dependent manner. Carbon 16-22 high mobility group box 1 Mus musculus 53-58 31999437-1 2020 The human DNA polymerase (pol) beta cancer variant K289M has altered polymerase activity in vitro, and the structure of wild-type pol beta reveals that the K289 side chain contributes to a network of stabilizing interactions in a C-terminal region of the enzyme distal to the active site. Carbon 230-231 DNA polymerase alpha 1, catalytic subunit Homo sapiens 130-138 31999437-6 2020 These results reveal the importance of the K289 mediated stabilizing network in the C-terminal region of pol beta and suggest an explanation as to why the K289M cancer variant is deficient in polymerase activity even though the 289 side chain is distal to the active site. Carbon 84-85 DNA polymerase alpha 1, catalytic subunit Homo sapiens 105-113 33079488-0 2020 Structural Engineering of SnS2 Encapsulated in Carbon Nanoboxes for High-Performance Sodium/Potassium-Ion Batteries Anodes. Carbon 47-53 sodium voltage-gated channel alpha subunit 11 Homo sapiens 26-30 33968889-11 2021 Besides, compared with X-rays, carbon ions increased the exposure of HMGB1 while relatively reduced the exposure levels of immunosuppressive factors IL-10 and TGF-beta. Carbon 31-37 high mobility group box 1 Mus musculus 69-74 33079488-4 2020 SnS2 nanoparticle is encapsulated in nitrogen-doped hollow carbon nanobox (SnS2 @C). Carbon 59-65 sodium voltage-gated channel alpha subunit 11 Homo sapiens 0-4 33079488-4 2020 SnS2 nanoparticle is encapsulated in nitrogen-doped hollow carbon nanobox (SnS2 @C). Carbon 59-65 sodium voltage-gated channel alpha subunit 11 Homo sapiens 75-79 33879638-8 2021 qRT-PCR analysis revealed that expression levels of phosphoglucose isomerase (PGI) and UDP-Glc 4-epimerase (UGE), two key genes involved in polysaccharide synthesis, varied depending on carbon source. Carbon 186-192 glucose-6-phosphate isomerase 1 Mus musculus 52-76 33079488-5 2020 The carbon nanoboxes accommodate the volume change and aggregation of SnS2 during cycling, and form 3D continuous conductive carbon matrix by close contact. Carbon 4-10 sodium voltage-gated channel alpha subunit 11 Homo sapiens 70-74 31967346-3 2020 Ric-8A is composed of a core armadillo-like domain and a flexible C-terminal tail. Carbon 66-67 RIC8 guanine nucleotide exchange factor A Homo sapiens 0-6 31967346-4 2020 Interaction of a conserved concave surface of its core domain with the Galpha C-terminus appears to mediate formation of the initial Ric-8A/GalphaGDP intermediate, followed by the formation of a stable nucleotide-free complex. Carbon 78-79 RIC8 guanine nucleotide exchange factor A Homo sapiens 133-139 31967346-6 2020 The distal portion of the C-terminal tail of Ric-8A forms a smaller secondary interface, which ostensibly binds the switch II region of Galpha, facilitating binding of GTP. Carbon 26-27 RIC8 guanine nucleotide exchange factor A Homo sapiens 45-51 31660580-8 2020 In addition, C-terminal truncated mutants of UGT1A9 and UGT2B7 still retained the suppressive capacity. Carbon 13-14 UDP glucuronosyltransferase family 1 member A9 Rattus norvegicus 45-51 33138308-1 2020 The mammalian Ccr4-Not complex, carbon catabolite repression 4 (Ccr4)-negative on TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts at different cellular levels to regulate gene expression. Carbon 32-38 CCR4-NOT core exoribonuclease subunit CCR4 Saccharomyces cerevisiae S288C 14-18 33138308-1 2020 The mammalian Ccr4-Not complex, carbon catabolite repression 4 (Ccr4)-negative on TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts at different cellular levels to regulate gene expression. Carbon 32-38 CCR4-NOT core exoribonuclease subunit CCR4 Saccharomyces cerevisiae S288C 64-68 31660580-8 2020 In addition, C-terminal truncated mutants of UGT1A9 and UGT2B7 still retained the suppressive capacity. Carbon 13-14 UDP glucuronosyltransferase family 2 member B7 Rattus norvegicus 56-62 33879638-8 2021 qRT-PCR analysis revealed that expression levels of phosphoglucose isomerase (PGI) and UDP-Glc 4-epimerase (UGE), two key genes involved in polysaccharide synthesis, varied depending on carbon source. Carbon 186-192 glucose-6-phosphate isomerase 1 Mus musculus 78-81 33933762-8 2021 In this Fenton-like reaction, the Fe@C-NB exhibits high efficiency and excellent stability without complex preparation methods; besides, the advantages of short reaction time and natural reaction conditions in Fe@C-NB/PMS system will promote the practical application of Fenton-like. Carbon 37-38 proline rich protein BstNI subfamily 1 Homo sapiens 218-221 31945665-6 2020 In vitro cell-based assay indicated that 6C was more effective in eliminating drug resistance of CYP1B1-overexpressed DU145 cells compared with other analogues. Carbon 41-43 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 97-103 33109186-15 2020 Moreover, blockade of purinergic P2 receptors (P2Rs) signaling using P2R antagonist, suramin, suppressed polyI:C-mediated increases of cilia-driven flow and CBF, indicating that TLR3-mediated ciliary activation depended on released extracellular ATP and the autocrine ATP-P2R loop. Carbon 111-112 toll like receptor 3 Homo sapiens 178-182 33388589-0 2021 In situ construction of hierarchical polyaniline/SnS2@carbon nanotubes on carbon fibers for high-performance supercapacitors. Carbon 54-60 sodium voltage-gated channel alpha subunit 11 Homo sapiens 49-53 33092507-6 2021 METHODS: A highly charged sodium mica (Na-mica-4) was synthesized and organofunctional by cationic exchange with an alkilamine, primary amine of 18 carbon atoms (C18-mica-4). Carbon 148-154 MHC class I polypeptide-related sequence A Homo sapiens 33-37 31724223-4 2020 Not only did we determine that Ras signaling inhibited TGF-beta-induced KLF5 acetylation and interfered with TGF-beta function in p15 induction and Myc repression, but also TGF-beta-induced SMAD3 C-terminal region phosphorylation was necessary for TGF-beta to induce KLF5 acetylation. Carbon 196-197 SMAD family member 3 Homo sapiens 190-195 31796534-5 2020 PPARdelta-YAP1 interaction occurred via the C-terminal domain of YAP1, and both TEAD and PPARE binding sites were required for SOX9 induction. Carbon 44-45 Yes1 associated transcriptional regulator Homo sapiens 10-14 31796534-5 2020 PPARdelta-YAP1 interaction occurred via the C-terminal domain of YAP1, and both TEAD and PPARE binding sites were required for SOX9 induction. Carbon 44-45 Yes1 associated transcriptional regulator Homo sapiens 65-69 33017144-1 2020 The biological synthesis of acetyl-coenzyme A (acetyl-CoA), catalyzed by acetyl-CoA synthase (ACS), is of biological significance and chemical interest acting as a source of energy and carbon. Carbon 185-191 acyl-CoA synthetase short chain family member 2 Homo sapiens 73-92 33388589-0 2021 In situ construction of hierarchical polyaniline/SnS2@carbon nanotubes on carbon fibers for high-performance supercapacitors. Carbon 74-80 sodium voltage-gated channel alpha subunit 11 Homo sapiens 49-53 33388589-3 2021 Herein, straight carbon nanotubes (CNTs) with radial orientation and high chemical/physical stability are served as nanoscale conductive skeletons on CFs for supporting the polyaniline (PANI)/SnS2. Carbon 17-23 sodium voltage-gated channel alpha subunit 11 Homo sapiens 192-196 33897464-4 2021 Medium- and long-chain fatty acids (6-12 and 13-21 carbon, respectively) target both FFAR1/GPR40 and FFAR4/GPR120. Carbon 51-57 free fatty acid receptor 4 Homo sapiens 101-106 33017144-1 2020 The biological synthesis of acetyl-coenzyme A (acetyl-CoA), catalyzed by acetyl-CoA synthase (ACS), is of biological significance and chemical interest acting as a source of energy and carbon. Carbon 185-191 acyl-CoA synthetase short chain family member 2 Homo sapiens 94-97 31892080-1 2020 In this study, imidazolium ionic liquids-derived carbon dots (ImCDs) were successfully synthesized and bonded on the surface of spherical porous silica as a new stationary phase (Sil-ImCDs) for hydrophilic interaction chromatography (HILIC). Carbon 49-55 STIL centriolar assembly protein Homo sapiens 179-182 33897464-4 2021 Medium- and long-chain fatty acids (6-12 and 13-21 carbon, respectively) target both FFAR1/GPR40 and FFAR4/GPR120. Carbon 51-57 free fatty acid receptor 4 Homo sapiens 107-113 31951129-4 2020 Junctions made of SAMs of n-alkanethiolates supported by Au were characterized with both DC and AC techniques, revealing that carbon-paint protective layers provide a solution to three well-know challenges in molecular junctions: series resistance of the leads, poor interface conductance and low effective contact area related to the roughness of the interfaces. Carbon 126-132 methionine adenosyltransferase 1A Homo sapiens 18-22 33646759-1 2021 Bioneutralization of pH by microbial fermentation of added carbon substrates is a promising new method for remediation of the 1.7 GT/yr of alkaline mining tailings produced globally. Carbon 59-65 phenylalanine hydroxylase Homo sapiens 21-23 32092957-7 2020 (2) The total carbon emissions per hectare in 2016 (6550.73 kgce/hm2) rose relative to the 2015 data (5617.92 kgce/hm2 at least in 2014) (5729.64 kgce/hm2). Carbon 14-20 cholinergic receptor muscarinic 2 Homo sapiens 65-68 33074436-1 2021 KEY MESSAGE: The tomato mutant Never ripe (Nr), a loss-of-function for the ethylene receptor SlETR3, shows enhanced growth, associated with increased carbon assimilation and a rewiring of the central metabolism. Carbon 150-156 ethylene receptor NR Solanum lycopersicum 93-99 33086048-4 2021 Here, we show that different environmental signals, in this case carbon sources, yield a unique single-molecule fluorescence pattern of foci of a key metabolic regulating transcription factor, Mig1, in the nucleus of the budding yeast, Saccharomyces cerevisiae. Carbon 65-71 transcription factor MIG1 Saccharomyces cerevisiae S288C 193-197 32075304-4 2020 The circular chromosome (4.39 Mbp) of the strain CHu59-6-5T has 64.4% G+C content and contains 4240 genes, of which a total of 3918 genes (92.4%) were functionally assigned to the COG (clusters of orthologous groups) database. Carbon 49-50 myelin basic protein Homo sapiens 30-33 33646759-2 2021 Here, we present the first study to systematically compare and optimize the efficacy of microbial inocula of varying diversities, structures, and provenance and organic carbon substrates of varying complexities on the rate and extent of pH bioneutralization in alkaline bauxite residue tailings. Carbon 169-175 phenylalanine hydroxylase Homo sapiens 237-239 33751064-4 2021 METHOD: A copper-based metal organic framework (Cu-MOF)/gold-platinum alloy nanoparticle(Au@Pt)-modified glassy carbon electrode (GCE) was developed via a simple wet chemical synthesis followed by electrochemical deposition of gold-platinum alloy nanoparticles onto the surface of a GCE. Carbon 112-118 lysine acetyltransferase 8 Homo sapiens 51-54 31767325-7 2020 From the perspective of function based on the 16S rRNA gene, aerobic ammonium oxidization, carbon assimilation, and chemoheterotrophic function may be the dominant processes in Southern Yap Trench sediments. Carbon 91-97 Yes1 associated transcriptional regulator Homo sapiens 186-189 32485516-2 2020 Results showed that it was the carbon source transformation and utilization especially the composition of poly-beta-hydroxyalkanoates (PHA) (mainly poly-beta-hydroxybutyrate (PHB) and poly-bhydroxyvalerate (PHV)) decided DPR performance, where the co-exist of HAc and HPr promoted the optimal nitrogen (85.77%) and phosphorus (91.37%) removals. Carbon 31-37 haptoglobin-related protein Homo sapiens 268-271 32485516-6 2020 Carbon source was demonstrated as the key point to stimulate the biodiversity and bioactivity related to DPR potential, and the operational strategy of carbon source addition was proposed based on the utilizing rules of HAc and HPr. Carbon 0-6 haptoglobin-related protein Homo sapiens 228-231 32485516-6 2020 Carbon source was demonstrated as the key point to stimulate the biodiversity and bioactivity related to DPR potential, and the operational strategy of carbon source addition was proposed based on the utilizing rules of HAc and HPr. Carbon 152-158 haptoglobin-related protein Homo sapiens 228-231 33325149-7 2021 Deletions of arcA and fnr significantly reduced the growth of Escherichia coli in M9 medium with a citrate carbon source. Carbon 107-113 arginine deiminase Escherichia coli 13-17 32778254-1 2020 A Fenton-like reaction and anaerobic ammonium oxidation (anammox) were combined to construct a novel process named FenTaMox for removing nitrogen (N) and organic carbon (measured as chemical oxidation demand (COD)). Carbon 162-168 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 209-212 32778254-6 2020 At a COD/N of 4, FenTaMox exhibited higher removal efficiencies of N and COD compared with that of the control, suggesting the application of FenTaMox for organic carbon- and N- removal. Carbon 163-169 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 5-15 31396885-2 2020 This article discusses electrochemical methods to synthesize platinum-graphene hybrid nanosheets (Pt-GR), and how these methods can be utilized to create a new modified electrode, the platinum-graphene nanohybrid glass carbon electrode (Pt-GR/GCE). Carbon 219-225 glycine decarboxylase Homo sapiens 237-246 31816386-10 2020 Immunofluorescence and luciferase assay showed that curcumin dramatically enhanced nuclear translocation and transcriptional activity of transcription factor EB (TFEB) in IPEC-J2 cells treated with H2O2, and it was ameliorated by co-treated with compound C, an Adenosine 5"-monophosphate (AMP)-activated protein kinase (AMPK) inhibitor, which means curcumin promotes TFEB transcript via AMPK signal pathway. Carbon 174-175 transcription factor EB Sus scrofa 137-160 31816386-10 2020 Immunofluorescence and luciferase assay showed that curcumin dramatically enhanced nuclear translocation and transcriptional activity of transcription factor EB (TFEB) in IPEC-J2 cells treated with H2O2, and it was ameliorated by co-treated with compound C, an Adenosine 5"-monophosphate (AMP)-activated protein kinase (AMPK) inhibitor, which means curcumin promotes TFEB transcript via AMPK signal pathway. Carbon 174-175 transcription factor EB Sus scrofa 162-166 33570421-1 2021 The Kapitza resistance (Rk) at the water-carbon nanotube (CNT) interface, with water on the inside of the nanotube, was investigated using molecular dynamics simulations. Carbon 41-47 ribokinase Homo sapiens 4-27 31633439-7 2020 The mutation frequencies at the HPRT (the hypoxanthine-guanine phosphoribosyl transferase) locus of all irradiation and half irradiation were at the same level and were higher than those of mixed population and half irradiation with inhibitor, respectively.Conclusion: There is evidence that the bystander effects for both lethality and mutagenicity occurred in the unirradiated half of the cells, in which only half of the cells were irradiated with the carbon ions. Carbon 455-461 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 32-36 31633439-7 2020 The mutation frequencies at the HPRT (the hypoxanthine-guanine phosphoribosyl transferase) locus of all irradiation and half irradiation were at the same level and were higher than those of mixed population and half irradiation with inhibitor, respectively.Conclusion: There is evidence that the bystander effects for both lethality and mutagenicity occurred in the unirradiated half of the cells, in which only half of the cells were irradiated with the carbon ions. Carbon 455-461 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 42-89 32833441-1 2020 Studies with acetylcholinesterase (AChE) inhibited by organophosphorus (OP) compounds with two chiral centers can serve as models or surrogates for understanding the rate, orientation and post-inhibitory mechanisms by the nerve agent, soman that possesses dual phosphorus and carbon chiral centers. Carbon 276-282 acetylcholinesterase Mus musculus 13-33 33594203-4 2021 HK2 knockdown and GCK expression rewired central carbon metabolism, stimulated mitochondrial respiration and restored essential metabolic functions of normal hepatocytes such as lipogenesis, VLDL secretion, glycogen storage. Carbon 49-55 hexokinase 2 Homo sapiens 0-3 32833441-1 2020 Studies with acetylcholinesterase (AChE) inhibited by organophosphorus (OP) compounds with two chiral centers can serve as models or surrogates for understanding the rate, orientation and post-inhibitory mechanisms by the nerve agent, soman that possesses dual phosphorus and carbon chiral centers. Carbon 276-282 acetylcholinesterase Mus musculus 35-39 32353659-3 2020 The hydrothermally synthesized nano-SnS2 mixed with chitosan solution (CHIT-SnS2) was drop-casted onto a glassy carbon electrode (GCE). Carbon 112-118 sodium voltage-gated channel alpha subunit 11 Homo sapiens 36-40 31866520-2 2020 Recently, independent studies have indicated that some hepatitis viruses develop abilities to hijack autophagy for their replication, such as hepatitis B (HBV) and C (HCV); these two viruses are structurally unrelated, but both of them can cause hepatitis, liver cirrhosis, and even hepatocellular carcinoma (HCC). Carbon 164-165 HCC Homo sapiens 283-313 31839525-2 2020 We have considered the disordered region that connects the N- and C-terminal halves in many eukaryotic ABC transporters, allowing all four consensus functional domains to be linked. Carbon 66-67 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 103-106 33492152-0 2021 Lewis Acid Activation of Fragment-Coupling Reactions of Tertiary Carbon Radicals Promoted by Visible-Light Irradiation of EDA Complexes. Carbon 65-71 ectodysplasin A Homo sapiens 122-125 32001754-4 2020 In this study, we have developed the closed formulae to estimate ABC, ABC4, GA, and GA5 topological indices for the graphical structures of boron nitride and carbon nanotube. Carbon 158-164 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 65-68 32901375-5 2020 SA1 and SA2 concentrations correlated well with the traffic-related pollutants NOx (r = 0.64 and 0.78) and equivalent black carbon (r = 0.53 and 0.51). Carbon 124-130 stromal antigen 2 Homo sapiens 8-11 33079186-3 2021 The eceriferum2 (cer2) mutant of Arabidopsis thaliana has a severe wax-deficient phenotype and specifically lacks waxes longer than 28 carbons, but the CER2 protein does not share sequence similarity with condensing enzymes. Carbon 135-142 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 4-15 32957294-3 2020 In the system of iron-carbon internal electrolysis coupled with persulfate, the iron-carbon internal electrolysis and persulfate had a significant mutual influence, exhibiting a wide range of pH in the treatment process. Carbon 22-28 phenylalanine hydroxylase Homo sapiens 192-194 32957294-3 2020 In the system of iron-carbon internal electrolysis coupled with persulfate, the iron-carbon internal electrolysis and persulfate had a significant mutual influence, exhibiting a wide range of pH in the treatment process. Carbon 85-91 phenylalanine hydroxylase Homo sapiens 192-194 32039147-9 2019 Using our synthetic 15N-labeled diUbs, we establish here how a C-terminally extended UBA domain of UBXN1 confers specificity to K6 diUb while the non-extended version of the domain does not show any linkage preference. Carbon 63-64 UBX domain protein 1 Homo sapiens 99-104 33045509-5 2021 The hydrothermal treatment generally increased the BET surface area of the activated carbons. Carbon 85-92 delta/notch like EGF repeat containing Homo sapiens 51-54 31961865-4 2020 The well-studied Mig1/2 orthologs ScMig1/2 mediate glucose repression in the yeast Saccharomyces cerevisiae; our data argue that C. albicans Mig1/2 function similarly as repressors of alternative carbon source utilization genes. Carbon 196-202 transcription factor MIG1 Saccharomyces cerevisiae S288C 17-23 31961865-10 2020 Finally, Mig1 is required for a puzzling feature of C. albicans biology that is not shared with S. cerevisiae: the essentiality of the Snf1 protein kinase, a central eukaryotic carbon metabolism regulator. Carbon 177-183 transcription factor MIG1 Saccharomyces cerevisiae S288C 9-13 31961865-11 2020 Our results integrate Mig1 and Mig2 into the C. albicans glucose repression pathway and illuminate connections among carbon control, pathogenicity, and Snf1 essentiality. Carbon 117-123 transcription factor MIG1 Saccharomyces cerevisiae S288C 22-26 31816612-4 2020 We had previously proposed a PID correction method for the errors in carbon-ion radiotherapy. Carbon 69-75 metastasis associated 1 family member 2 Homo sapiens 29-32 32583004-3 2020 APOL1 inhibited cell proliferation in a non-fermentable carbon source, such as glycerol, while it had no effect on proliferation in fermentable carbon sources, such as galactose. Carbon 56-62 apolipoprotein L1 Homo sapiens 0-5 33513731-5 2021 The finding showed that the lignin isolated using citric acid maintained to pH 3 resulted in briquette with 72% fixed carbon content, excellent 99.7% DSI, and a calorific value equivalent to coal-based briquette. Carbon 118-124 phenylalanine hydroxylase Homo sapiens 76-78 32838944-3 2020 Our previous study showed that KPNA3 is involved in interferon production during PCV2 infection induced by Poly I:C and ISD (Interferon stimulatory DNA). Carbon 82-83 karyopherin subunit alpha 3 Homo sapiens 31-36 32843557-2 2020 Vaginal microbial communities are typically dominated by one or a few well-adapted microbes which are able to survive in a narrow pH range and are adapted to live on host-derived carbon sources, likely sourced from glycogen and mucin present in the vaginal environment. Carbon 179-185 LOC100508689 Homo sapiens 228-233 31723002-6 2020 Conversely, GSK3beta phosphorylated serine and threonine sites in the C-terminal domain of NDRG1, and limited the protein stability of NDRG1. Carbon 0-1 glycogen synthase kinase 3 beta Homo sapiens 12-20 31767681-3 2020 Here, we demonstrate that a human spastin binds weakly to unmodified peptides from the C-terminal segment of human tubulin a1A/B. Carbon 87-88 spastin Homo sapiens 34-41 31900681-4 2020 The nanostructured tin disulfide (SnS2) synthesized by hydrothermal technique and 3A-amino-3A-deoxy-(2AS, 3AS)-beta-cyclodextrin hydrate were sequentially modified onto the disposable screen-printed carbon electrode (SPCE) via titration using a micropipette. Carbon 199-205 sodium voltage-gated channel alpha subunit 11 Homo sapiens 34-38 33415980-1 2021 The biological global carbon cycle is largely regulated through microbial nickel enzymes, including carbon monoxide dehydrogenase (CODH), acetyl coenzyme A synthase (ACS), and methyl coenzyme M reductase (MCR). Carbon 22-28 acyl-CoA synthetase short chain family member 2 Homo sapiens 138-164 31830156-2 2020 In particular, with the carbon chain increasing to n-butane, a main component in liquefied petroleum gas (LPG) and shale oil gas, chemically different C-C bonds ((C-C)alpha,beta and (C-C)beta,beta") will be involved in cleavages. Carbon 24-30 fibrillin 2 Homo sapiens 163-172 33415980-1 2021 The biological global carbon cycle is largely regulated through microbial nickel enzymes, including carbon monoxide dehydrogenase (CODH), acetyl coenzyme A synthase (ACS), and methyl coenzyme M reductase (MCR). Carbon 22-28 acyl-CoA synthetase short chain family member 2 Homo sapiens 166-169 32428768-0 2020 Photoredox catalysis of As(III) by constructed CSnS bonds: Using biomass as templates leads to bio-carbon/SnS2 nanosheets capable of the efficient photocatalytic conversion of As(III) and calcium arsenate capture. Carbon 99-105 sodium voltage-gated channel alpha subunit 11 Homo sapiens 106-110 33378163-4 2021 In addition, REE concentrations within and down-gradient of an organic carbon/limestone PRB were significantly reduced to <1% of influent levels. Carbon 71-77 RB transcriptional corepressor 1 Homo sapiens 88-91 32428768-1 2020 In this paper, a new interface design strategy for bio-carbon/SnS2 nanosheets equipped with CSnS bonds was proposed by using biomass as a template for the efficient photocatalytic conversion of As(III). Carbon 55-61 sodium voltage-gated channel alpha subunit 11 Homo sapiens 62-66 32829711-12 2020 CONCLUSIONS: Our study provides evidence that altered CX3CL1-CX3CR1 and/or CD200-CD200R pathways, emerging after prenatal immune challenge with LPS and Poly I:C, might be involved in the aetiology of schizophrenia. Carbon 0-1 Cd200 molecule Rattus norvegicus 75-80 31896687-4 2020 87-98) show that in budding yeast, the fork protection complex Tof1-Csm3 interacts physically with DNA topoisomerase I (Top1) at replication forks through the C-terminal domain of Tof1. Carbon 68-69 Tof1p Saccharomyces cerevisiae S288C 63-67 31896687-4 2020 87-98) show that in budding yeast, the fork protection complex Tof1-Csm3 interacts physically with DNA topoisomerase I (Top1) at replication forks through the C-terminal domain of Tof1. Carbon 68-69 Tof1p Saccharomyces cerevisiae S288C 180-184 33446657-3 2021 Here we show that inhibition of PHGDH, the first step in the SSP, cooperates with serine and glycine depletion to inhibit one-carbon metabolism and cancer growth. Carbon 126-132 3-phosphoglycerate dehydrogenase Mus musculus 32-37 31629361-1 2020 Elevated circulating C-terminal agrin fragment (CAF) is a marker of neuromuscular junction degradation and sarcopenia. Carbon 21-22 lysine acetyltransferase 2B Homo sapiens 48-51 31563141-6 2020 Gene expression of aurora kinases A-C was evaluated by quantitative RT-PCR and western blot, respectively, in spinal cords at 1, 3, 7, and 14 d after CCI. Carbon 36-37 aurora kinase A Rattus norvegicus 19-35 31759040-8 2020 Moreover, C-terminal end of the Gasdermin D molecule is also cleaved by the caspase-1. Carbon 10-11 gasdermin D Homo sapiens 32-43 31706959-6 2020 RT-PCR analysis showed expression of N- and C-terminal fragments of TRPV3-mRNA in the adult rat cerebellum. Carbon 4-5 transient receptor potential cation channel, subfamily V, member 3 Rattus norvegicus 68-73 31835770-2 2019 The activated carbon was tested by SEM, EDX, BET, XRD, FTIR, and XPS. Carbon 14-20 delta/notch like EGF repeat containing Homo sapiens 45-48 31835770-3 2019 This activated carbon exhibited a high BET surface area of 831 m2 g-1 with the average pore diameter and pore volume reaching 2.52 nm and 0.45 m3 g-1, respectively. Carbon 15-21 delta/notch like EGF repeat containing Homo sapiens 39-42 31817656-6 2019 Using pharmacological and dominant-negative inhibition of SMAD3 C-terminal phosphorylation, we further show that the migration-inhibiting effect of SMAD3 is independent of its activation by TGF-beta. Carbon 64-65 SMAD family member 3 Homo sapiens 58-63 31817656-6 2019 Using pharmacological and dominant-negative inhibition of SMAD3 C-terminal phosphorylation, we further show that the migration-inhibiting effect of SMAD3 is independent of its activation by TGF-beta. Carbon 64-65 SMAD family member 3 Homo sapiens 148-153 31738543-4 2019 Herein, we report the first synthesis of a pi-conjugated polymeric segment (PS1) of armchair single-walled carbon nanotubes (SWCNTs). Carbon 107-113 presenilin 1 Homo sapiens 76-79 31738543-7 2019 Possessing unique structural and physical properties, this long pi-extended polymer PS1 can provide new insight for the development of bottom-up syntheses of uniform carbon nanotube segments and potential applications in electron- and hole-transport devices. Carbon 166-172 presenilin 1 Homo sapiens 84-87 31797120-2 2019 The surface of a glassy carbon electrode was modified with core-shell nanofibers, multi-walled carbon nanotubes and gold nanoparticles that were covalently modified with the MUC1-binding aptamer. Carbon 24-30 mucin 1, cell surface associated Homo sapiens 174-178 31477820-1 2019 Exposing a microbial community to alternating absence and presence of carbon substrate in aerobic conditions is an effective strategy for enrichment of storage polymers (polyhydroxybutyrate, PHB) producing microorganisms. Carbon 70-76 prohibitin 1 Homo sapiens 191-194 31154625-11 2019 Poly I:C stimulation increased mRNA expression of retinoic-acid-inducible protein I (RIG-I), melanoma-differentiation-associated gene 5 (MDA5), IFN-stimulated gene factor 3 (ISG3) complex, and IFN-stimulated genes (IRF7, ISG15, IFIT1, OAS1); nicotine attenuated mRNA expression only in WT cells. Carbon 7-8 ISG15 ubiquitin like modifier Homo sapiens 221-226 31154625-11 2019 Poly I:C stimulation increased mRNA expression of retinoic-acid-inducible protein I (RIG-I), melanoma-differentiation-associated gene 5 (MDA5), IFN-stimulated gene factor 3 (ISG3) complex, and IFN-stimulated genes (IRF7, ISG15, IFIT1, OAS1); nicotine attenuated mRNA expression only in WT cells. Carbon 7-8 interferon induced protein with tetratricopeptide repeats 1 Homo sapiens 228-233 31154625-11 2019 Poly I:C stimulation increased mRNA expression of retinoic-acid-inducible protein I (RIG-I), melanoma-differentiation-associated gene 5 (MDA5), IFN-stimulated gene factor 3 (ISG3) complex, and IFN-stimulated genes (IRF7, ISG15, IFIT1, OAS1); nicotine attenuated mRNA expression only in WT cells. Carbon 7-8 2'-5'-oligoadenylate synthetase 1 Homo sapiens 235-239 31444411-3 2019 Here, we report that the gene encoding glycine decarboxylase (GLDC), which catalyzes the first and rate-limiting step in glycine breakdown with the production of the one-carbon unit 5,10-methylene-tetrahydrofolate, is a direct transcriptional target of MYCN. Carbon 170-176 glycine decarboxylase Homo sapiens 39-60 31444411-3 2019 Here, we report that the gene encoding glycine decarboxylase (GLDC), which catalyzes the first and rate-limiting step in glycine breakdown with the production of the one-carbon unit 5,10-methylene-tetrahydrofolate, is a direct transcriptional target of MYCN. Carbon 170-176 glycine decarboxylase Homo sapiens 62-66 31444411-6 2019 Metabolomic profiling reveals that GLDC knockdown disrupts purine and central carbon metabolism and reduces citrate production, leading to a decrease in the steady-state levels of cholesterol and fatty acids. Carbon 78-84 glycine decarboxylase Homo sapiens 35-39 31599029-9 2019 We also identified three C-terminal sequences in choanoflagellates that bind a choanoflagellate PDZ domain, the Monsiga brevicollis SHANK1 PDZ domain (mbSHANK1), with endogenously-relevant affinities, despite a lack of conservation with the targets of a homologous human PDZ domain, SHANK1. Carbon 25-26 SH3 and multiple ankyrin repeat domains 1 Homo sapiens 132-138 31599029-9 2019 We also identified three C-terminal sequences in choanoflagellates that bind a choanoflagellate PDZ domain, the Monsiga brevicollis SHANK1 PDZ domain (mbSHANK1), with endogenously-relevant affinities, despite a lack of conservation with the targets of a homologous human PDZ domain, SHANK1. Carbon 25-26 SH3 and multiple ankyrin repeat domains 1 Homo sapiens 153-159 31504961-0 2019 Carbon nanomaterials stimulate HMGB1 release from macrophages and induce cell migration and invasion. Carbon 0-6 high mobility group box 1 Mus musculus 31-36 31504961-4 2019 In this work, we found that 7-day exposure of 2.5 mg/kg/day CNMs, including C60, single-walled carbon nanotubes (SWCNTs), and Graphene oxides (GOs) significantly elevated the level of HMGB1 in blood and lung lavage fluids in C57BL/6 mice. Carbon 95-101 high mobility group box 1 Mus musculus 184-189 31550607-1 2019 Wild type (WT) HIV-1 envelope (Env) protein cytoplasmic tails (CTs) appear to be composed of membrane-proximal, N-terminal unstructured regions, and three C-terminal amphipathic helices. Carbon 63-64 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 31-34 31753031-6 2019 This interaction was mediated by the C-terminal tail regions of KIF5A and the third PDZ domain of PSD-95. Carbon 37-38 discs large MAGUK scaffold protein 4 Homo sapiens 98-104 31752232-2 2019 This paper focuses on simulating the flexural behavior of reinforced concrete beam strengthened by prestressed C/GFRP (Carbon-Glass hybrid Fiber Reinforced Polymer) with different hybrid ratios and prestress levels. Carbon 119-125 GTP cyclohydrolase I feedback regulator Homo sapiens 111-117 31586034-9 2019 We observed that RNF186 and Sestrin-2 bind each other through distinct C-terminal motifs and that Lys-13 in Sestrin-2 is a putative ubiquitin-acceptor site. Carbon 71-72 ring finger protein 186 Homo sapiens 17-23 31586034-9 2019 We observed that RNF186 and Sestrin-2 bind each other through distinct C-terminal motifs and that Lys-13 in Sestrin-2 is a putative ubiquitin-acceptor site. Carbon 71-72 sestrin 2 Homo sapiens 28-37 31512136-4 2019 Results revealed that when medium carbon concentration increased from 4.76 to 95.24 mmol/L, CO2 absorption ratio increased by about 12%, 10%, 12%, and 11% at medium depths of 10, 20, 40, and 80 cm, with the initial pH 10.6 to 9.7 by bubbling CO2, respectively. Carbon 34-40 phenylalanine hydroxylase Homo sapiens 215-217 31584736-8 2019 Of note, a combination of LPS and the double-stranded RNA, polyinosinic-polycytidylic acid (poly(I:C)), was most potent in increasing FVIII immunogenicity, followed by LPS + R848 (resiquimod). Carbon 99-101 coagulation factor VIII Homo sapiens 134-139 31087782-2 2019 Herein, a novel nanoflower-like electrocatalyst comprising few-layer nitrogen-doped graphene-encapsulated nickel-copper alloy directly on a porous nitrogen-doped graphic carbon framework (denoted as Nix Cuy @ NG-NC) is successfully synthesized using a facile and scalable method through calcinating the carbon, copper, and nickel hydroxy carbonate composite under inert atmosphere. Carbon 303-309 BCL2 interacting protein 3 like Homo sapiens 199-202 31550123-4 2019 Specifically, Co5(PO4)2(OH)4 deposited on glassy carbon electrode (loading amount 0.553 mg cm-2) can exhibit an unprecedented overpotential of 254 mV to drive a current density of 10 mA cm-2 with a small Tafel slope of 57 mV dec-1 in alkaline electrolytes, which outperforms the ones of CO3(PO4)2 (370 mV) and Co(OH)2 (360 mV) as well as other advanced catalysts. Carbon 49-55 deleted in esophageal cancer 1 Homo sapiens 226-231 31601812-4 2019 According to the developed mechanism-based analytical model, we demonstrate that sulfur utilization is limited by the solubility of lithium-polysulfides and further conversion from lithium-polysulfides to Li2S is limited by the electronically accessible surface area of the carbon matrix. Carbon 274-280 ATP binding cassette subfamily A member 12 Homo sapiens 205-208 31604311-5 2019 Deletion of the C-terminal segment reduces Raf activity. Carbon 16-17 zinc fingers and homeoboxes 2 Homo sapiens 43-46 31582797-6 2019 Ubiquitination of RPA2 was inhibited by HERC2 depletion and rescued by reintroduction of the C-terminal fragment of HERC2. Carbon 43-44 replication protein A2 Homo sapiens 18-22 31516609-4 2019 The objective of the present study was to investigate the effects of high-LET carbon ions and low-LET X-rays on the expression of VEGF and MMPs, and to identify the associated mechanisms in the Tca8113 TSCC cell line. Carbon 78-84 matrix metallopeptidase 2 Homo sapiens 139-143 31516609-8 2019 These findings indicate that compared with low-LET X-ray irradiation, high-LET carbon ions possess higher biological efficacy in inhibiting the invasive ability of Tca8113 cells via reduction of VEGF, MMP-2 and MMP-9 expression. Carbon 79-85 matrix metallopeptidase 2 Homo sapiens 201-206 31832316-3 2019 In this strategy, the hollow carbon spheres are decorated with MoS2 (HCS/MoS2) as the S carrier (S@HCS/MoS2). Carbon 29-35 holocarboxylase synthetase Homo sapiens 69-72 31832316-3 2019 In this strategy, the hollow carbon spheres are decorated with MoS2 (HCS/MoS2) as the S carrier (S@HCS/MoS2). Carbon 29-35 holocarboxylase synthetase Homo sapiens 99-102 31663062-3 2019 Phage SA2 had a double-stranded DNA genome with a length of 89,055 bp and a G + C content of 31.9%. Carbon 80-81 stromal antigen 2 Homo sapiens 6-9 31476275-3 2019 This as-developed metal-free amino-rich hierarchical-network carbon (amino-HNC) framework directly supported on carbon paper can catalyze OER at a quite low overpotential of 281 mV and a small Tafel slope of 96 mV dec-1 in an acid solution, and maintain ~98% of its initial catalytic activity after 100 h oxygen evolution operation. Carbon 61-67 deleted in esophageal cancer 1 Homo sapiens 214-219 31476275-3 2019 This as-developed metal-free amino-rich hierarchical-network carbon (amino-HNC) framework directly supported on carbon paper can catalyze OER at a quite low overpotential of 281 mV and a small Tafel slope of 96 mV dec-1 in an acid solution, and maintain ~98% of its initial catalytic activity after 100 h oxygen evolution operation. Carbon 112-118 deleted in esophageal cancer 1 Homo sapiens 214-219 31252257-2 2019 The anode and cathode fibers were prepared through modification with glucose dehydrogenase and bilirubin oxidase, respectively, on multi-walled carbon nanotube-coated carbon fibers. Carbon 144-150 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 69-90 31252257-2 2019 The anode and cathode fibers were prepared through modification with glucose dehydrogenase and bilirubin oxidase, respectively, on multi-walled carbon nanotube-coated carbon fibers. Carbon 167-173 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 69-90 31411029-0 2019 MOF-Derived Co,N Codoped Carbon/Ti Mesh Counter Electrode for High-Efficiency Quantum Dot Sensitized Solar Cells. Carbon 25-31 lysine acetyltransferase 8 Homo sapiens 0-3 31289106-7 2019 However, a key finding is that, whereas the presence of primary CYP24A1 substrate was found to induce NMR peak broadening focused on the putative recognition site alpha-helix 3 of rat adrenodoxin, the interaction in the presence of 1alpha(OH)D3, which is lacking the carbon-25 hydroxyl, results in disruption of the NMR peak broadening pattern, thus indicating a ligand-induced nonspecific protein interaction. Carbon 267-273 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 64-71 31252114-1 2019 In this work, anthraquinone-2-sulfonate (AQS) was covalently immobilized onto activated carbon cloth (ACC), to be used as redox mediator for the reductive decolorization of reactive red 2 (RR2) by an anaerobic consortium. Carbon 88-94 adenosine deaminase RNA specific B2 (inactive) Homo sapiens 182-187 31067518-3 2019 A 2 mm thick aero-GaN sample exhibits electromagnetic shielding properties in the X-band similar to solid structures based on metal foams or carbon nanomaterials. Carbon 141-147 gigaxonin Homo sapiens 18-21 31485527-9 2019 The time of UV irradiation gives the longer energy for the bond formation between the positive C atoms of the carbonyl group and the O atoms of the hydroxyl group at C-6 atoms of mannose and galactose. Carbon 95-96 complement C6 Homo sapiens 166-169 31434956-0 2019 Prolonged exposure to multi-walled carbon nanotubes dysregulates intestinal mir-35 and its direct target MAB-3 in nematode Caenorhabditis elegans. Carbon 35-41 mir-35 Caenorhabditis elegans 76-82 31039457-9 2019 Changes in the material texture, BET surface area and pore volume can be easily controlled via carbon content in samples. Carbon 95-101 delta/notch like EGF repeat containing Homo sapiens 33-36 32662793-0 2020 MOF-derived ultrasmall CoSe2 nanoparticles encapsulated by an N-doped carbon matrix and their superior lithium/sodium storage properties. Carbon 70-76 lysine acetyltransferase 8 Homo sapiens 0-3 33488208-1 2020 In this study, carbon nanotubes (CNTs) added polyacrylonitrile/polypyrrole (PAN/PPy) electrospun nanofibers were produced. Carbon 15-21 adenosine deaminase 2 Homo sapiens 76-79 31786302-0 2020 A novel peptide binding to the C-terminal domain of connective tissue growth factor for the treatment of bleomycin-induced pulmonary fibrosis. Carbon 31-32 cellular communication network factor 2 Homo sapiens 52-83 31786302-1 2020 Using phage display technology, 810A was developed as a novel peptide, which binds to the C-terminal domain of connective tissue growth factor (CTGF). Carbon 90-91 cellular communication network factor 2 Homo sapiens 111-142 31786302-1 2020 Using phage display technology, 810A was developed as a novel peptide, which binds to the C-terminal domain of connective tissue growth factor (CTGF). Carbon 90-91 cellular communication network factor 2 Homo sapiens 144-148 32126728-6 2020 BET surface area of 532 m2 g-1 was obtained for NiMoS2/Carbon catalysts from the nitrogen physisorption analysis. Carbon 55-61 delta/notch like EGF repeat containing Homo sapiens 0-3 32424363-4 2020 Flt3L-secreting T cells expanded intratumoral conventional type 1 DCs and substantially increased host DC and T cell activation when combined with immune agonists poly (I:C) and anti-4-1BB. Carbon 171-173 fms related receptor tyrosine kinase 3 ligand Homo sapiens 0-5 32680977-0 2020 Co-exposure to multi-walled carbon nanotube and lead ions aggravates hepatotoxicity of nonalcoholic fatty liver via inhibiting AMPK/PPARgamma pathway. Carbon 28-34 peroxisome proliferator activated receptor gamma Mus musculus 132-141 32274517-8 2020 In this regard, both, genetic engineering and the identification of various layers of regulation, respectively, points to glycine decarboxylase (GDC) as the key enzyme to regulate and adjust the photorespiratory carbon flow. Carbon 212-218 glycine decarboxylase Homo sapiens 122-143 32640766-0 2020 Effective Removal of Pb(II) Ions by Electrospun PAN/Sago Lignin-based Activated Carbon Nanofibers. Carbon 80-86 adenosine deaminase 2 Homo sapiens 48-51 32328734-3 2020 During growth on hexadecane as sole carbon source, the activity of 3-hydroxyacyl-CoA dehydrogenase, a beta-oxidation pathway enzyme, was measured. Carbon 36-42 succinate-CoA ligase ADP-forming subunit beta Homo sapiens 100-106 31865509-3 2020 Prior studies have focused on the regulatory K+ transport and NAD-binding (KTN) domain in the C-terminus of the thylakoid carrier KEA3 but the localization of this domain remains unclear. Carbon 94-95 K+ efflux antiporter 3 Arabidopsis thaliana 130-134 32578398-3 2020 In the bioelectronic skin, the nanovesicles containing the hTRPA1 nociceptive ion channel protein reacts to cold-pain stimuli, and it is electrically monitored through carbon nanotube transistor devices based on floating electrodes. Carbon 168-174 transient receptor potential cation channel subfamily A member 1 Homo sapiens 59-65 32656445-0 2020 Multiprobe Assay for Clinical SEPT9 Methylation Based on the Carbon Dot-Modified Liquid-Exfoliated Graphene Field Effect Transistor with a Potential to Present a Methylation Panorama. Carbon 61-67 septin 9 Homo sapiens 30-35 32656445-3 2020 Herein, an electronic method for determining SEPT9 methylation in CRC patients is proposed by using the carbon dot-modified liquid exfoliated graphene field effect transistor (CDs-LEG-FET) as the DNAm sensor, the specifically designed probes to capture the SEPT9 gene and the immunologic recognition to recognize 5-methylcytosine (5mC) positions on the anchored sequences. Carbon 104-110 septin 9 Homo sapiens 45-50 32656445-3 2020 Herein, an electronic method for determining SEPT9 methylation in CRC patients is proposed by using the carbon dot-modified liquid exfoliated graphene field effect transistor (CDs-LEG-FET) as the DNAm sensor, the specifically designed probes to capture the SEPT9 gene and the immunologic recognition to recognize 5-methylcytosine (5mC) positions on the anchored sequences. Carbon 104-110 septin 9 Homo sapiens 257-262 32604028-8 2020 In the second case, we built a trajectory file for the ecto-5"-nucleotidase using the LiGRO program to study the carbon alpha pincer angles, to define the secondary structure of the proteins and to analyze the Modevectors. Carbon 113-119 5'-nucleotidase ecto Homo sapiens 55-75 32432255-2 2020 The as-synthesized unique FeCo/SWCNT catalyst exhibits remarkable oxygen electrocatalysis performance, especially oxygen evolution reaction activity and superior stability owing to the efficient synergistic effect between FeCo alloy and single-layer carbon regarding the electronic interaction and surface protection, achieving an overpotential (eta) of 253 mV at 10 mA cm-2 and a Tafel slope of 44 mV dec-1 in 1.0 M KOH solution while presenting outstanding stability after being tested for 50 hours. Carbon 250-256 deleted in esophageal cancer 1 Homo sapiens 402-407 32432474-11 2020 The alpha- and beta-carbon addition reactions generate 1,3- (RA1) and 1,2-diol (RB1) adduct-radicals, respectively. Carbon 20-26 RB transcriptional corepressor 1 Homo sapiens 80-83 32545661-3 2020 Calculations were carried out for a disc made of carbon friction composites material Termar-ADF. Carbon 49-55 destrin, actin depolymerizing factor Homo sapiens 92-95 32347850-1 2020 We report the synergistic adsorption and activation of CO2 by using magnesium oxide anchored into a hollow carbon sphere (MgO/HCS) as an efficient catalyst for electrochemical reduction of CO2 (ERC). Carbon 107-113 holocarboxylase synthetase Homo sapiens 126-129 32045805-3 2020 To solve this problem, we introduce a simple and efficient way to prepare a photocatalyst, ZnIn2S4 grown on nitrogen-doped hollow carbon spheres (ZIS-NHC), which is an effective catalyst that can used to reduce aqueous Cr(VI). Carbon 130-136 zinc finger RANBP2-type containing 2 Homo sapiens 146-149 32196699-7 2020 Numerical verification shows that the present models are as accurate as or better than the standard FMO2 method in total energy with fragmentation at sp3 carbon atoms. Carbon 154-160 flavin containing dimethylaniline monoxygenase 2 Homo sapiens 100-104 32061804-4 2020 Herein, we review the genes involved in folate transport and one carbon metabolism thus far identified as contributing variants that influence human NTD risk, and place these findings in the context of our evolving understanding of the complex genetic architecture underlying these defects. Carbon 65-71 fuzzy planar cell polarity protein Homo sapiens 149-152 32203884-6 2020 Proteins involved in carbon and energy metabolism comprised 23% of total identified proteins include mainly glyceraldehyde-3-phosphate dehydrogenase, malate dehydrogenase, transaldolase, and isocitrate dehydrogenase. Carbon 21-27 glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic Cicer arietinum 108-148 32203884-6 2020 Proteins involved in carbon and energy metabolism comprised 23% of total identified proteins include mainly glyceraldehyde-3-phosphate dehydrogenase, malate dehydrogenase, transaldolase, and isocitrate dehydrogenase. Carbon 21-27 malate dehydrogenase Cicer arietinum 150-170 32193289-2 2020 Here we investigated miR-26a function in MM and tested single-wall carbon nanotube delivery of miR-26a in vitro and in vivo. Carbon 67-73 microRNA 26a-1 Homo sapiens 95-102 31867791-3 2020 For example, the Aida Lab has pioneered conducting "bucky gel" by dispersing carbon nanotubes in ionic liquids as well as "aqua materials", in which a tiny amount of additive renders water mechanically robust. Carbon 77-83 axin interactor, dorsalization associated Homo sapiens 17-21 31990134-2 2020 The present study focuses on influence of mixed feed carbon substrates during the induction phases of glycoengineered P. pastoris cultivation, for recombinant huIFNalpha2b (Human Interferon alpha2b) production by employing calorimetric (Biological heat rate, qB ) and respirometric (OUR& CER) measurements. Carbon 53-59 interferon alpha 2 Homo sapiens 179-197 32066088-1 2020 An interdigitated immunosensor for Cystatin C detection based on polypyrrole/carbon nanotube electrochemical capacitor is described. Carbon 77-83 cystatin C Homo sapiens 35-45 32007561-11 2020 Although CYP17A1 exhibited no catalytic activity towards the 5alpha-reduced intermediates, once the C4-C5 double bond and the keto group at C3 were reduced, both the hydroxylation and lyase reactions proceeded efficiently. Carbon 100-105 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 9-16 31846033-0 2020 Corrigendum to "Carbon Nanomaterials Stimulate HMGB1 Release From Macrophages and Induce Cell Migration and Invasion". Carbon 16-22 high mobility group box 1 Homo sapiens 47-52 31941629-9 2020 The combined use of 137Cs and the perceptual model provides reliable SDR estimates benefiting the appraisals of the redistribution of eroded carbon. Carbon 141-147 caveolae associated protein 2 Homo sapiens 69-72 32081014-7 2020 Comparison of the acetylome from Hat1+/+ cells grown on galactose and glucose demonstrated that there are large carbon source-dependent changes in the mammalian acetylome where the acetylation of enzymes involved in glycolysis was the most affected. Carbon 112-118 histone acetyltransferase 1 Homo sapiens 33-37 32318554-8 2020 In 2001, Metabolix Inc. filed a patent concerning genetically modified and stable organisms, e.g., Escherichia coli, producing P4HB and copolymers from inexpensive carbon sources. Carbon 164-170 prolyl 4-hydroxylase subunit beta Homo sapiens 127-131 32273347-6 2020 RESULTS: In vitro-generated CD103+ cDC1s produced cDC1-associated factors such as interleukin-12p70 and CXCL10, and demonstrated antigen cross-presentation activity on stimulation with the toll-like receptor 3 agonist polyinosinic:polycytidylic acid (poly I:C). Carbon 28-29 chemokine (C-X-C motif) ligand 10 Mus musculus 104-110 32208468-9 2020 The fluorescence quenching property of carbon dots has been utilized to identify detection limit of 0.25, 0.5, and 2 ng ml-1 for diazinon, amicarbazone, and glyphosate, respectively. Carbon 39-45 interleukin 17F Homo sapiens 120-124 32257815-5 2020 The Mtrr gt mutation in mice was previously shown to disrupt one-carbon metabolism and cause a wide-spectrum of developmental phenotypes and late adult-onset macrocytic anaemia. Carbon 65-71 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Mus musculus 4-8 32024695-6 2020 We found here that C-terminally truncated Drosophila TnT (TpnT-CD70) retains binding of tropomyosin, troponin I, and troponin C, indicating a preserved core structure of TnT. Carbon 19-20 Troponin C isoform 4 Drosophila melanogaster 117-127 32017918-4 2020 Nuclear magnetic resonance analysis reveals that SEW84 binds to the C-terminal domain of Aha1 to weaken its asymmetric binding to Hsp90. Carbon 68-69 activator of HSP90 ATPase activity 1 Homo sapiens 89-93 32050768-0 2020 Hierarchical Porous Carbon Arising from MOF Encapsulated Bacteria and its Energy Storage Potential. Carbon 20-26 lysine acetyltransferase 8 Homo sapiens 40-43 32218789-10 2020 Gene expression of IFNbeta, IFNlambda2 and IFN-stimulated genes (ISGs) were upregulated in response to poly I:C and a further increase in gene expression was observed following IC87114 treatment. Carbon 110-111 interferon lambda 2 Homo sapiens 28-38 32218789-11 2020 In addition, IC87114 enhanced poly I:C-induced phosphorylation of IRF3. Carbon 14-15 interferon regulatory factor 3 Homo sapiens 66-70 31862235-10 2020 An example of a prochiral unnatural substrate for sphingosine kinase 2, fingolimod, has an sp3 hybridized prochiral carbon and also contains a prochiral plane. Carbon 116-122 sphingosine kinase 2 Homo sapiens 50-70 32004873-5 2020 The nPM lacks water-insoluble PAHs (polycyclic aromatic hydrocarbons) and is depleted by >50% in bioactive metals (e.g., copper, iron, nickel), inorganic ions, black carbon, and other organic compounds. Carbon 61-67 nucleophosmin 1 Homo sapiens 4-7 31744771-5 2020 We further recognised that the C NMR chemical shifts of the nominal phenyl carbons (C(3)/C(7) and C(4)/C(6)) encode information for intramolecular hydrogen bonding network formed by GA conformers. Carbon 68-82 complement C6 Homo sapiens 103-107 31994401-0 2020 Synthesis of Strophasterols C, E, and F. The synthesis of strophasterols C, E, and F has been accomplished from a 14,15-secoergostane derivative via a 1,3-dipolar cycloaddition of a nitrile oxide intermediate to simultaneously install an isolated cyclopentane ring and a C23 oxygen functionality in a diastereoselective manner and a regio- and diastereoselective selenohydroxylation of an olefinic intermediate under thermodynamic conditions. Carbon 58-74 nucleolin Homo sapiens 271-274 31948223-3 2020 For this purpose, zeolitic imidazolate framework-8 (ZIF-8) was selected as a MOF model to entrap carbon dot (CD) and curcumin (CCM) during its self-assembly, which produces CD/CCM@ZIF-8. Carbon 97-103 lysine acetyltransferase 8 Homo sapiens 77-80 32085439-15 2020 Consequently, SUMO3, ALC1, POLE4, PCBP4, MUTYH expression correlated with the higher RBE of carbon ions. Carbon 92-98 chromodomain helicase DNA binding protein 1 like Homo sapiens 21-25 31858096-2 2020 Cobalt magnetic polystyrene microsphere derived carbon (C-Co@PST) as an adsorbent was prepared by in situ polymerization reaction and further annealing treatment. Carbon 48-54 sulfotransferase family 1A member 1 Homo sapiens 61-64 31993622-3 2020 Herein, quinone and ester-type oxygen-modified carbon has been successfully obtained by chemical activation with alkali, which is beneficial to the absorption of PF6- together with lithium ions, which would largely improve the electrode kinetics. Carbon 47-53 sperm associated antigen 17 Homo sapiens 162-165 32040646-0 2020 Hydrogen Can Passivate Carbon Impurities in Mg-Doped GaN. Carbon 23-29 gigaxonin Homo sapiens 53-56 32040646-5 2020 This suggests that the co-doped hydrogen not only passivate MgGa, but also can passivate carbon impurities in Mg-doped p-GaN. Carbon 89-95 gigaxonin Homo sapiens 121-124 31914411-2 2020 This activity is provided by the C-terminal helicase domain of viral nonstructural protein 3 (NS3). Carbon 33-34 helicase for meiosis 1 Homo sapiens 44-52 31845935-1 2020 Red emitting carbon dots derived from p-phenylenediamine (PPDCDs) were successfully prepared and grafted onto the surface of silica spheres, which served as a new stationary phase (Sil-PPDCDs) for liquid chromatography with excellent hydrophilic selectivity. Carbon 13-19 STIL centriolar assembly protein Homo sapiens 181-184 31845935-5 2020 The successful application of the Sil-PPDCDs stationary phase again indicated the great potential of carbon dots as a new modifier of the stationary phase in high performance liquid chromatography, and this kind of new stationary phase is very promising to be used for the separation of hydrophilic compounds in biochemical and pharmaceutical analysis. Carbon 101-107 STIL centriolar assembly protein Homo sapiens 34-37 31772076-0 2020 Apple ALMT9 requires a conserved C-terminal domain for malate transport underlying fruit acidity. Carbon 33-34 aluminum-activated malate transporter 9 Malus domestica 6-11 32013110-4 2020 The p42, p44, p46, p48 and p52 isoform proteins were each able to induce RNase-mediated rRNA cleavage in response to poly(I:C) when overexpressed in HEK293 cells. Carbon 124-126 interferon induced protein 44 Homo sapiens 9-12 31980627-3 2020 Kindlin-2, through its C-terminal region, binds to and stabilizes MafA, which activates insulin expression. Carbon 23-24 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) Mus musculus 66-70 31969821-7 2019 The AMPK inhibitor compound C significantly attenuated Eth-induced autophagy and inhibited proliferation. Carbon 28-29 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 4-8 31425914-2 2020 The performances of the carbon materials are evaluated by catalytic activation of perroxymonosulfate (PMS) for phenol degradation. Carbon 24-30 proline rich protein BstNI subfamily 1 Homo sapiens 102-105 31839203-8 2020 On the basis of our findings, we propose the model that C-terminal deletion interferes with MN1"s interaction molecules related to the ubiquitin-mediated proteasome pathway, including RING1, and increases the amount of the mutant protein; this increase leads to the dysregulation of MN1 target genes by inhibiting rapid MN1 protein turnover. Carbon 56-57 ring finger protein 1 Homo sapiens 184-189 31931994-0 2020 Multiwalled carbon nanotubes bound beta-galactosidase: It"s activity, stability and reusability. Carbon 12-18 galactosidase beta 1 Homo sapiens 35-53 31931306-1 2020 INTRODUCTION: Glyburide is an approved anti-diabetes drug binding to the sulfonylurea receptors-1 (SUR-1) and substrate of solute carrier (SLC) transporters, which can be isotopically radiolabelled with carbon-11 for PET imaging. Carbon 203-209 ATP binding cassette subfamily C member 8 Homo sapiens 73-97 31931306-1 2020 INTRODUCTION: Glyburide is an approved anti-diabetes drug binding to the sulfonylurea receptors-1 (SUR-1) and substrate of solute carrier (SLC) transporters, which can be isotopically radiolabelled with carbon-11 for PET imaging. Carbon 203-209 ATP binding cassette subfamily C member 8 Homo sapiens 99-104 31805844-1 2020 Background and Purpose- Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is an autosomal dominant small vessel disease caused by C-terminal frameshift mutations in the TREX1 gene that encodes the major mammalian 3" to 5" DNA exonuclease. Carbon 110-111 three prime repair exonuclease 1 Homo sapiens 211-216 32021158-6 2019 Results: The results show silver-doped ordered mesoporous carbons to positively condition cell viability, with a cell viability percentage >70% even for 10 wt% Ag, to modulate the expression of inflammatory cytokines and of genes involved in tissue repair (KRT6a, VEGFA, IVN) and remodeling (MMP9, TIMP3) in different cell systems. Carbon 58-65 keratin 6A Homo sapiens 257-262 31888075-7 2019 (4) The average value in agricultural carbon emission intensity in the region is 767.79 kg/hm2, and the order based on intensity is Xinjiang > Shaanxi > Ningxia > Gansu > Qinghai. Carbon 38-44 cholinergic receptor muscarinic 2 Homo sapiens 91-94 31852930-3 2019 The activated carbon prepared under optimum conditions showed a predominantly microporous structure with a BET surface area of 2263 m2 g-1, a total pore volume of 1.37 cm3 g-1 and a micro pore volume of 1.004 cm3 g-1. Carbon 14-20 delta/notch like EGF repeat containing Homo sapiens 107-110 33417790-6 2019 The Sil-MA water solution with the addition of a photoinitiator (LAP) allows the opening, under UV radiation, of a double carbon-carbon bond and radical polymerization. Carbon 122-128 STIL centriolar assembly protein Homo sapiens 4-7 33417790-6 2019 The Sil-MA water solution with the addition of a photoinitiator (LAP) allows the opening, under UV radiation, of a double carbon-carbon bond and radical polymerization. Carbon 129-135 STIL centriolar assembly protein Homo sapiens 4-7 31817918-6 2019 Moreover, we observed that rubioncolin C inhibited the TNF-alpha- and LPS-induced NF-kappaB activation upstream of the p65 protein, which contributed to rubioncolin C-induced cell death. Carbon 27-40 RELA proto-oncogene, NF-kB subunit Homo sapiens 119-122 31817918-6 2019 Moreover, we observed that rubioncolin C inhibited the TNF-alpha- and LPS-induced NF-kappaB activation upstream of the p65 protein, which contributed to rubioncolin C-induced cell death. Carbon 153-166 RELA proto-oncogene, NF-kB subunit Homo sapiens 119-122 31763647-1 2019 We report a multi-shelled two-dimensional metal-organic framework (MOF), which is transferred to a Co/Ni-embedded bimetallic N-doped porous carbon. Carbon 140-146 lysine acetyltransferase 8 Homo sapiens 42-71 32042798-8 2019 After intervention of AMPK activity, the proportion of memory T cells in the spleen reduced as compared to the AS group and AS + solvent group; the pro proportion of memory T cells in HFD groups was markedly higher than in the normal group and this increase was more evident in the AS + Compound C than in the AS + A-769662 group. Carbon 287-288 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 22-26 31546117-3 2019 Herein, C16mimPF6, an ionic liquid, was introduced in the self-assembly process of poly-benzoxazine to obtain a unique skin-tissue-bone structured hierarchical porous carbon with homogeneous N, P co-doping after carbonization. Carbon 167-173 sperm associated antigen 17 Homo sapiens 8-17 31546117-4 2019 As the key component, C16mimPF6 works not only as a structure-directing agent to form a hierarchical structure through microphase separation mechanism, thereby promoting the transfer of ion and electron, but also as a heteroatom precursor to contribute an additional pseudocapacitance by doping phosphorus atoms on carbon matrix. Carbon 315-321 sperm associated antigen 17 Homo sapiens 22-31 31721414-3 2019 Herein, a Li2 S/Si full cell is designed with a Li2 S cathode incorporated by titanium nitride (TiN) polysulfide immobilizer within parallel hollow carbon (PHC). Carbon 148-154 ATP binding cassette subfamily A member 12 Homo sapiens 10-13 31784551-5 2019 Transcription by RNAPII is heavily controlled by phosphorylation of the C-terminal domain of its largest subunit Rpb1. Carbon 72-73 RNA polymerase II subunit A Homo sapiens 113-117 31490586-2 2019 The activated carbon-based flexible supercapacitor device with MOG electrolyte has a wide potential window of 2.1 V with high retention of specific capacitance compared to the traditional polyvinyl alcohol (PVA) based gel. Carbon 14-20 myelin oligodendrocyte glycoprotein Homo sapiens 63-66 31200015-9 2019 Hence, the new FDH classification scheme and the electron donor analysis provide an improved base for developing FDH-facilitated CO2 reduction as a viable step in the utilization of CO2 as carbon source for green production of chemicals. Carbon 189-195 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 15-18 31200015-9 2019 Hence, the new FDH classification scheme and the electron donor analysis provide an improved base for developing FDH-facilitated CO2 reduction as a viable step in the utilization of CO2 as carbon source for green production of chemicals. Carbon 189-195 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 113-116 31568723-3 2019 Here, we present nine derivatives of the cobalt bis(dicarbollide)(1-) anion substituted at the boron or carbon sites by alkysulfamide group(s) as highly specific and selective inhibitors of CAIX. Carbon 104-110 carbonic anhydrase 9 Homo sapiens 190-194 31806973-2 2019 Methods: The prodrug of CA4 was synthesized with stearyl chloride (18-carbon chain), palmitoyl chloride (16-carbon chain), myristoyl chloride (14-carbon chain), decanoyl chloride (10-carbon chain), and hexanoyl chloride (6-carbon chain) at the 3"-position of the CA4. Carbon 70-76 carbonic anhydrase 4 Homo sapiens 24-27 31806973-2 2019 Methods: The prodrug of CA4 was synthesized with stearyl chloride (18-carbon chain), palmitoyl chloride (16-carbon chain), myristoyl chloride (14-carbon chain), decanoyl chloride (10-carbon chain), and hexanoyl chloride (6-carbon chain) at the 3"-position of the CA4. Carbon 108-114 carbonic anhydrase 4 Homo sapiens 24-27 31806973-2 2019 Methods: The prodrug of CA4 was synthesized with stearyl chloride (18-carbon chain), palmitoyl chloride (16-carbon chain), myristoyl chloride (14-carbon chain), decanoyl chloride (10-carbon chain), and hexanoyl chloride (6-carbon chain) at the 3"-position of the CA4. Carbon 108-114 carbonic anhydrase 4 Homo sapiens 24-27 31806973-2 2019 Methods: The prodrug of CA4 was synthesized with stearyl chloride (18-carbon chain), palmitoyl chloride (16-carbon chain), myristoyl chloride (14-carbon chain), decanoyl chloride (10-carbon chain), and hexanoyl chloride (6-carbon chain) at the 3"-position of the CA4. Carbon 108-114 carbonic anhydrase 4 Homo sapiens 24-27 31806973-2 2019 Methods: The prodrug of CA4 was synthesized with stearyl chloride (18-carbon chain), palmitoyl chloride (16-carbon chain), myristoyl chloride (14-carbon chain), decanoyl chloride (10-carbon chain), and hexanoyl chloride (6-carbon chain) at the 3"-position of the CA4. Carbon 108-114 carbonic anhydrase 4 Homo sapiens 24-27 31806973-8 2019 The results of the in vivo pharmacokinetic and tissue distribution studies indicated that the reduced rate of CA4 release with a long carbon chain could prolong the circulation time and increase the drug concentration in the tumor tissue. Carbon 134-140 carbonic anhydrase 4 Homo sapiens 110-113 31655496-3 2019 In this work, a gas chromatography coupled to carbon isotope ratio mass spectrometry (GC-C-IRMS) method was developed and validated to distinguish their exogenous origin from the endogenous one. Carbon 46-52 guanylate cyclase 2C Homo sapiens 86-90 31398569-0 2019 Carbon quantum dots @ Pd-SnS2 nanocomposite: The role of CQDs @ Pd nanoclusters in enhancing photocatalytic reduction of aromatic nitro compounds. Carbon 0-6 sodium voltage-gated channel alpha subunit 11 Homo sapiens 25-29 31421459-2 2019 Methylenetetrahydrofolate dehydrogenase 1 like (MTHFD1L), an enzyme in the folate cycle, is involved in formate generation and therefore in one-carbon metabolism. Carbon 144-150 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Homo sapiens 48-55 31661879-3 2019 Importantly, DHDDS encompasses a C-terminal region, which does not converge with any known conserved domains. Carbon 33-34 dehydrodolichyl diphosphate synthase subunit Homo sapiens 13-18 31661879-8 2019 Our model suggests that the DHDDS C-terminus forms a helix-turn-helix motif, tightly packed against the core catalytic domain. Carbon 34-35 dehydrodolichyl diphosphate synthase subunit Homo sapiens 28-33 31624245-3 2019 Integrating anti-MYCN ChIP-seq and gene expression profiles of neuroblastoma patients revealed the metabolic enzymes, MTHFD2 and PAICS, required for one-carbon metabolism and purine biosynthesis were concomitantly upregulated, which were more susceptible to metastatic neuroblastoma. Carbon 153-159 phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase Homo sapiens 129-134 31658680-3 2019 NS5, which consists of a C-terminal RdRp domain and an N-terminal methyltransferase domain, plays a pivotal role in genome replication and capping. Carbon 25-26 Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens 0-3 31490505-0 2019 Bimetallic MOF-templated synthesis of alloy nanoparticle-embedded porous carbons for oxygen evolution and reduction reactions. Carbon 73-80 lysine acetyltransferase 8 Homo sapiens 11-14 31807524-0 2019 Comparison of the effects of photon, proton and carbon-ion radiation on the ecto-calreticulin exposure in various tumor cell lines. Carbon 48-54 tripartite motif containing 33 Homo sapiens 76-80 31807524-4 2019 However, there is limited knowledge describing the effects of proton and carbon-ion radiation on ecto-CRT exposure. Carbon 73-79 tripartite motif containing 33 Homo sapiens 97-101 31807524-5 2019 Hence, we investigated ecto-CRT exposure in multiple human carcinoma cell lines irradiated by proton and carbon-ion in comparison to photon. Carbon 105-111 tripartite motif containing 33 Homo sapiens 23-27 31807524-13 2019 Photon and proton at 10 Gy increased the most ecto-CRT exposure (P<0.05), while carbon-ion increased most ecto-CRT exposure at 4 Gy rather than 10 or 2 Gy. Carbon 83-89 tripartite motif containing 33 Homo sapiens 109-113 31446906-9 2019 Proteomic analysis revealed that two candidate proteins were obtained in the hippocampus of polyI:C-treated mice, including aldehyde dehydrogenase family 1 member L1 (ALDH1L1) and collapsin response mediator protein 5 (CRMP5). Carbon 98-99 dihydropyrimidinase-like 5 Mus musculus 180-217 31446906-9 2019 Proteomic analysis revealed that two candidate proteins were obtained in the hippocampus of polyI:C-treated mice, including aldehyde dehydrogenase family 1 member L1 (ALDH1L1) and collapsin response mediator protein 5 (CRMP5). Carbon 98-99 dihydropyrimidinase-like 5 Mus musculus 219-224 31616422-10 2019 In salmonid CHSE-214 cells, we observed that the Irak3-splice variant that prominently expresses the C-terminal domain significantly quenched the stimulation-dependent production of interleukin-1beta and interleukin-8, but not the production of other immune regulators. Carbon 12-13 interleukin-1 receptor-associated kinase 3 Oncorhynchus mykiss 49-54 31546910-3 2019 Here, for the first time, a buckypaper sensor composed of oxygenated amorphous carbon (a-COx)/graphite (G) nanofilaments is developed. Carbon 79-85 cytochrome c oxidase subunit 8A Homo sapiens 89-92 31519952-8 2019 Acyl chain length alterations in ceramides also suggested roles for FATP4 in esterifying saturated non-hydroxy and beta-hydroxy FAs with at least 25 carbons and saturated or unsaturated omega-hydroxy FAs with at least 30 carbons to CoA. Carbon 149-156 solute carrier family 27 (fatty acid transporter), member 4 Mus musculus 68-73 31519952-8 2019 Acyl chain length alterations in ceramides also suggested roles for FATP4 in esterifying saturated non-hydroxy and beta-hydroxy FAs with at least 25 carbons and saturated or unsaturated omega-hydroxy FAs with at least 30 carbons to CoA. Carbon 221-228 solute carrier family 27 (fatty acid transporter), member 4 Mus musculus 68-73 31448623-3 2019 Specifically, pH-driven charge reversal of zwitterionic carbon dots leads to immediate electrostatic conversion between the two building blocks from attraction to repulsion. Carbon 56-62 phenylalanine hydroxylase Homo sapiens 14-16 31397458-2 2019 This hierarchical homogeneous structure combined the Ga, Ga2O3 and carbon frameworks (from Ga-MOF) to exhibit excellent electrochemical performance. Carbon 67-73 lysine acetyltransferase 8 Homo sapiens 94-97 31500303-4 2019 Using the colon ascendens stent peritonitis (CASP) model, we demonstrate that IFNbeta-/- and type I IFN receptor (IFNAR1)-/- mice were less susceptible to sepsis after pre-stimulation with the viral mimetic poly(I:C). Carbon 214-216 interferon (alpha and beta) receptor 1 Mus musculus 114-120 31854894-7 2019 The total carbon storage of phytOC in the bamboo forest soil, at 23.45 t hm-2, was significantly higher than that of other soil use methods (P<0.05). Carbon 10-16 cholinergic receptor muscarinic 2 Homo sapiens 73-77 31552063-5 2019 Through transient and stable expression assays in Nicotiana benthamiana and Arabidopsis thaliana, we demonstrate that IYO contains two nuclear localization signals (NLSs), located at the N- and C-terminus of the protein, which mediate the interaction with the NLS-receptor IMPA4 and the import of the protein into the nucleus. Carbon 194-195 RPAP1-like, carboxy-terminal protein Arabidopsis thaliana 118-121 31289106-0 2019 Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate. Carbon 88-94 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 41-61 31298961-4 2019 Materials and Methods: The effect of C-82, an active metabolite of PRI-724, on the expression of TGF-beta1 and alpha-smooth muscle actin (SMA) was examined on fibroblasts and macrophages. Carbon 37-38 transforming growth factor, beta 1 Mus musculus 97-106 31331996-3 2019 We identified an epigenetic regulator, METHIONINE SYNTHASE1 (ATMS1), which catalyzes the synthesis of methionine (Met) in the one-carbon metabolism pathway. Carbon 130-136 Cobalamin-independent synthase family protein Arabidopsis thaliana 61-66 31331996-8 2019 These results suggest that ATMS1 is required for DNA and histone methylations through its function in the one-carbon metabolism pathway, indicating the complex interplay between metabolism and epigenetic regulation. Carbon 110-116 Cobalamin-independent synthase family protein Arabidopsis thaliana 27-32 31466258-3 2019 TGA showed that carbon fillers improved the resistance to thermal and thermo-oxidative degradation under both air and nitrogen atmospheres. Carbon 16-22 T-box transcription factor 1 Homo sapiens 0-3 31323180-3 2019 In this paper, we report a simple one-step hydrothermal synthesis of SnS2/graphene/SnS2 (SnS2/rGO/SnS2) composite with ultrathin SnS2 nanosheets covalently decorated on both sides of reduced graphene oxide sheets via C-S bonds. Carbon 217-218 sodium voltage-gated channel alpha subunit 11 Homo sapiens 69-73 31323180-3 2019 In this paper, we report a simple one-step hydrothermal synthesis of SnS2/graphene/SnS2 (SnS2/rGO/SnS2) composite with ultrathin SnS2 nanosheets covalently decorated on both sides of reduced graphene oxide sheets via C-S bonds. Carbon 217-218 sodium voltage-gated channel alpha subunit 11 Homo sapiens 83-87 31323180-3 2019 In this paper, we report a simple one-step hydrothermal synthesis of SnS2/graphene/SnS2 (SnS2/rGO/SnS2) composite with ultrathin SnS2 nanosheets covalently decorated on both sides of reduced graphene oxide sheets via C-S bonds. Carbon 217-218 sodium voltage-gated channel alpha subunit 11 Homo sapiens 83-87 31323180-3 2019 In this paper, we report a simple one-step hydrothermal synthesis of SnS2/graphene/SnS2 (SnS2/rGO/SnS2) composite with ultrathin SnS2 nanosheets covalently decorated on both sides of reduced graphene oxide sheets via C-S bonds. Carbon 217-218 sodium voltage-gated channel alpha subunit 11 Homo sapiens 83-87 31323180-3 2019 In this paper, we report a simple one-step hydrothermal synthesis of SnS2/graphene/SnS2 (SnS2/rGO/SnS2) composite with ultrathin SnS2 nanosheets covalently decorated on both sides of reduced graphene oxide sheets via C-S bonds. Carbon 217-218 sodium voltage-gated channel alpha subunit 11 Homo sapiens 83-87 31263822-5 2019 The transistors consisting of only one-dimensional carbon nanotubes and two-dimensional graphene oxide show an ultralow operating voltage of less than -1 V, an extraordinary subthreshold swing (SS) of 170 mV dec-1, a low threshold voltage (Vth) of -0.3 V and a high carrier mobility up to 105 cm2 V-1 s-1. Carbon 51-57 deleted in esophageal cancer 1 Homo sapiens 208-213 31337681-5 2019 When S. cerevisiae grows on a nonfermentable carbon source, its gluconeogenic enzymes Fbp1, Icl1, Mdh2, and Pck1 are expressed and long-lived. Carbon 45-51 fructose 1,6-bisphosphate 1-phosphatase Saccharomyces cerevisiae S288C 86-90 31337681-5 2019 When S. cerevisiae grows on a nonfermentable carbon source, its gluconeogenic enzymes Fbp1, Icl1, Mdh2, and Pck1 are expressed and long-lived. Carbon 45-51 isocitrate lyase 1 Saccharomyces cerevisiae S288C 92-96 31273977-0 2019 One Pot Generation of Blue and Red Carbon Dots in One Binary Solvent System for Dual Channel Detection of Cr3+ and Pb2+ Based on Ion Imprinted Fluorescence Polymers. Carbon 35-41 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 106-109 31319551-2 2019 Here, we present a miniaturized immunosensor using disposable screen-printed carbon electrodes (SPCEs) for the detection of GH with high sensitivity. Carbon 77-83 gonadotropin releasing hormone receptor Rattus norvegicus 124-126 31379793-7 2019 Importantly, the regulation of Thi2p differs from a previous regulatory network that functions when glucose is the sole carbon source, which suggests that the function of Thi2p depends on the carbon source. Carbon 120-126 Thi2p Saccharomyces cerevisiae S288C 31-36 31379793-7 2019 Importantly, the regulation of Thi2p differs from a previous regulatory network that functions when glucose is the sole carbon source, which suggests that the function of Thi2p depends on the carbon source. Carbon 120-126 Thi2p Saccharomyces cerevisiae S288C 171-176 31379793-7 2019 Importantly, the regulation of Thi2p differs from a previous regulatory network that functions when glucose is the sole carbon source, which suggests that the function of Thi2p depends on the carbon source. Carbon 192-198 Thi2p Saccharomyces cerevisiae S288C 31-36 31379793-7 2019 Importantly, the regulation of Thi2p differs from a previous regulatory network that functions when glucose is the sole carbon source, which suggests that the function of Thi2p depends on the carbon source. Carbon 192-198 Thi2p Saccharomyces cerevisiae S288C 171-176 31260277-7 2019 Strongly polarized Fe-C bonds are observed where the negative charge is mostly centered at the mu2-C yldiide ligands. Carbon 22-23 adaptor related protein complex 1 subunit mu 2 Homo sapiens 95-98 31943985-2 2019 Sm-MOF doping plays an important role in regulating the structure of the gel and promoting the formation of samarium oxide in an amorphous state that is uniformly dispersed among the carbon spheres. Carbon 183-189 lysine acetyltransferase 8 Homo sapiens 3-6 30734493-3 2019 Here, the efficacy of the 0D N doped carbon quantum dots (N-CQDs) is demonstrated in accelerating the charge separation and transfer and thereby boosting the activity of a narrow-bandgap SnS2 photocatalytic system. Carbon 37-43 sodium voltage-gated channel alpha subunit 11 Homo sapiens 187-191 30878936-1 2019 Herein, an effective method was developed to integrate carbon microwires on Ti mesh (denoted as CM/TiM) to fabricate high-performance anodes with long-time stability in microbial fuel cell. Carbon 55-61 Rho guanine nucleotide exchange factor 5 Homo sapiens 99-102 30878936-2 2019 CM/TiM was synthesized by colonizing filamentous fungi on the bread modified Ti mesh followed by carbonization, which could convert the attached mycelium into carbon microwires (denoted as CM). Carbon 97-103 Rho guanine nucleotide exchange factor 5 Homo sapiens 3-6 30878936-3 2019 Benefiting from the biocompatibility and 3D interlaced structure of carbon microwires, the biomass accumulation (1027 +- 83 mug cm-2) of CM/TiM have been significantly improved nearly 3 folds, thus the fabricated CM/TiM demonstrated 2-fold higher current density (12.19 +- 0.07 A m-2) with significantly increased stability compared with TiM. Carbon 68-74 Rho guanine nucleotide exchange factor 5 Homo sapiens 140-143 30878936-3 2019 Benefiting from the biocompatibility and 3D interlaced structure of carbon microwires, the biomass accumulation (1027 +- 83 mug cm-2) of CM/TiM have been significantly improved nearly 3 folds, thus the fabricated CM/TiM demonstrated 2-fold higher current density (12.19 +- 0.07 A m-2) with significantly increased stability compared with TiM. Carbon 68-74 Rho guanine nucleotide exchange factor 5 Homo sapiens 216-219 30878936-3 2019 Benefiting from the biocompatibility and 3D interlaced structure of carbon microwires, the biomass accumulation (1027 +- 83 mug cm-2) of CM/TiM have been significantly improved nearly 3 folds, thus the fabricated CM/TiM demonstrated 2-fold higher current density (12.19 +- 0.07 A m-2) with significantly increased stability compared with TiM. Carbon 68-74 Rho guanine nucleotide exchange factor 5 Homo sapiens 216-219 30878936-4 2019 Therefore, the present high power output, chemical stability and hydrophilic carbon microwires make CM/TiM stable, scalable and environmentally sustainable anodes in bioelectrochemical systems. Carbon 77-83 Rho guanine nucleotide exchange factor 5 Homo sapiens 103-106 31195604-2 2019 The anticorrosion effect of TPP for carbon steel was researched by static weight-loss method, on-line simulated dynamic test, electrochemical measurement, and scanning electron microscopy (SEM). Carbon 36-42 trehalose-phosphate phosphatase A-like Nicotiana tabacum 28-31 31209804-8 2019 In contrast, Pam3Cys and Poly(I:C), the agonist of TLR1/2 or TLR3, partly inhibited FI-RSV-enhanced lung inflammation. Carbon 32-34 toll like receptor 3 Homo sapiens 61-65 30844566-1 2019 Fe and N functionalized hollow carbon spheres (Fe/N-HCS) with hierarchically porous structure are constructed. Carbon 31-37 holocarboxylase synthetase Homo sapiens 52-55 30849732-3 2019 In this study, a bioanalytical approach was used, measuring oxidative stress (Nrf2 activity), genotoxicity (micronucleus test), and aryl hydrocarbon receptor (AhR) activation to evaluate an innovative water treatment process, including suspended ion exchange, ozonation, in-line coagulation, ceramic microfiltration, and granular activated carbon. Carbon 142-148 aryl hydrocarbon receptor Homo sapiens 159-162 31017164-2 2019 In this study, three-dimensional (3D) freestanding multi-doped hollow carbon spheres (N-Co-Fe-HCS) with a layer thickness of 30 nm, which contained multiple active sites of the heteroatom N and transition metals (Co and Fe), were synthesized via a simple template method (with SiO2 as the template) and cost-efficient in situ self-polymerization, self-adsorption/reduction and carbonization strategies. Carbon 70-76 holocarboxylase synthetase Homo sapiens 94-97 31017164-3 2019 Moreover, a series of hollow carbon sphere composites of the same family (N-HCS, N-Co-HCS and N-Fe-HCS) were prepared by this sensible process using the same method and precursors but different doping elements. Carbon 29-35 holocarboxylase synthetase Homo sapiens 76-79 31018808-4 2019 Higher percentages of TLR2, TLR3, TLR4, and TLR7 were expressed on such lymphocytes, and the TLR agonists PGN, Poly I:C, LPS, and R848 induced a higher level of IFN-gamma. Carbon 118-119 toll-like receptor 2 Mus musculus 22-26 30387134-0 2019 Toll-like receptor 3 agonist poly I:C reinforces the potency of cytotoxic chemotherapy via the TLR3-UNC93B1-IFN-beta signaling axis in paclitaxel-resistant colon cancer. Carbon 36-37 toll like receptor 3 Homo sapiens 0-20 30387134-0 2019 Toll-like receptor 3 agonist poly I:C reinforces the potency of cytotoxic chemotherapy via the TLR3-UNC93B1-IFN-beta signaling axis in paclitaxel-resistant colon cancer. Carbon 36-37 toll like receptor 3 Homo sapiens 95-99 30387134-0 2019 Toll-like receptor 3 agonist poly I:C reinforces the potency of cytotoxic chemotherapy via the TLR3-UNC93B1-IFN-beta signaling axis in paclitaxel-resistant colon cancer. Carbon 36-37 interferon beta 1 Homo sapiens 108-116 31107031-5 2019 The results showed that the simulated carbon storage was accurate, with average correlation coefficient (r), root mean square error (RMSE) and relative bias (rBIAS) being 0.75, 7.24 Mg C hm-2 and -2.57 Mg C hm-2, respectively. Carbon 38-44 cholinergic receptor muscarinic 2 Homo sapiens 187-198 31013971-1 2019 We have demonstrated that the aqueous two-phase extraction (ATPE) can differentiate between large diameter single-walled carbon nanotubes (CNTs) by electrical character. Carbon 121-127 ATP synthase F1 subunit epsilon Homo sapiens 60-64 30788873-4 2019 Taking the SnS2 /SnO2 couple as an example, SnS2 /SnO2 nanosheet heterostructures on carbon nanofibers (CNFs), named C@SnS2 /SnO2 , were designed and synthesized. Carbon 85-91 sodium voltage-gated channel alpha subunit 11 Homo sapiens 11-15 30788873-4 2019 Taking the SnS2 /SnO2 couple as an example, SnS2 /SnO2 nanosheet heterostructures on carbon nanofibers (CNFs), named C@SnS2 /SnO2 , were designed and synthesized. Carbon 85-91 sodium voltage-gated channel alpha subunit 11 Homo sapiens 44-48 30788873-4 2019 Taking the SnS2 /SnO2 couple as an example, SnS2 /SnO2 nanosheet heterostructures on carbon nanofibers (CNFs), named C@SnS2 /SnO2 , were designed and synthesized. Carbon 85-91 sodium voltage-gated channel alpha subunit 11 Homo sapiens 44-48 30924822-0 2019 Correction: MOF@activated carbon: a new material for adsorption of aldicarb in biological systems. Carbon 26-32 lysine acetyltransferase 8 Homo sapiens 12-15 30924822-1 2019 Correction for "MOF@activated carbon: a new material for adsorption of aldicarb in biological systems" by Carlos Alberto Fernandes de Oliveira et al., Chem. Carbon 30-36 lysine acetyltransferase 8 Homo sapiens 16-19 30958856-4 2019 Overexpression of SFH1 in the strain defective in Psd1 restored its growth on non-fermentable carbon sources and increased the intracellular and mitochondrial PE levels. Carbon 94-100 phosphatidylserine decarboxylase 1 Saccharomyces cerevisiae S288C 50-54 30677184-2 2019 This pathway contains four enzymes termed DmdA, DmdB, DmdC and DmdD/AcuH, which together catabolize DMSP to acetylaldehyde and methanethiol as carbon and sulfur sources respectively. Carbon 143-149 sarcoglycan gamma Homo sapiens 42-46 30859742-2 2019 Herein, Nix Mny Coz O nanowire (x + y + z = 1)/carbon nanotube (CNT) composite microspheres with a 3D interconnected conductive network structure (3DICN-NCS) are prepared via a spray-drying method. Carbon 47-53 BCL2 interacting protein 3 like Homo sapiens 8-11 30785716-0 2019 Fabrication of SnS2/Mn2SnS4/Carbon Heterostructures for Sodium-Ion Batteries with High Initial Coulombic Efficiency and Cycling Stability. Carbon 28-34 sodium voltage-gated channel alpha subunit 11 Homo sapiens 15-19 30672090-3 2019 The as-fabricated product exhibits a low overpotential of 224 mV on a glassy carbon electrode at 10 mA cm-2 (even lower down to 181 mV when supported on Ni foam) with a Tafel slope of 44 mV dec-1 for OER in an alkaline solution. Carbon 77-83 deleted in esophageal cancer 1 Homo sapiens 190-195 30801094-2 2019 The hT1R1 was modified and mounted onto a signal amplification system on a glassy carbon electrode surface, and the response current towards four umami ligands (sodium glutamate (MSG), disodium inosinate (IMP), disodium guanylate (GMP), and disodium succinate (SUC)) was measured. Carbon 82-88 taste 1 receptor member 1 Homo sapiens 4-9 30816702-0 2019 MOF-Derived Hybrid Hollow Submicrospheres of Nitrogen-Doped Carbon-Encapsulated Bimetallic Ni-Co-S Nanoparticles for Supercapacitors and Lithium Ion Batteries. Carbon 60-66 lysine acetyltransferase 8 Homo sapiens 0-3 32123461-0 2019 Ag2S nanocrystallites deposited over polyamidoamine grafted carbon nanotubes: An efficient NIR active photothermal agent. Carbon 60-66 angiotensin II receptor type 1 Homo sapiens 0-4 32123461-1 2019 A novel NIR (near infrared) active photothermal agent, CNTs-PAMAM-Ag2S has been synthesized by covalent grafting of polyamidoamine (PAMAM) to carbon nanotubes (CNTs) and subsequent deposition of Ag2S nanocrystallites. Carbon 142-148 angiotensin II receptor type 1 Homo sapiens 66-70 31317323-0 2019 Aptamer-based fluorometric determination for mucin 1 using gold nanoparticles and carbon dots. Carbon 82-88 mucin 1, cell surface associated Homo sapiens 45-52 31302781-2 2019 The surface of a glassy carbon electrode (GCE) was first modified with nitrogen-doped graphene and then gold nanoparticles and graphene quantum dots electrodeposited on it to obtain an architecture of type GQD/AuNP/NG/GCE. Carbon 24-30 glycine cleavage system protein H Homo sapiens 42-45 31277462-4 2019 The effect of AMPS comonomer on the carbon nanofibers was studied using scanning electron microscopy (SEM), differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA) and Raman spectrum. Carbon 36-42 adenylosuccinate lyase Homo sapiens 14-18 31277462-8 2019 Moreover, the carbon nanofibers derived from P(AN-co-AMPS) precursor nanofibers had the better graphite-like structures (XG = 46.889). Carbon 14-20 adenylosuccinate lyase Homo sapiens 53-57 31277462-9 2019 Therefore, the AMPS is a promising candidate comonomer to produce high performance carbon fibers. Carbon 83-89 adenylosuccinate lyase Homo sapiens 15-19 31943985-1 2019 A samarium-doped carbon aerogel cathode (CA-Sm) for high-performance lithium-sulfur batteries was successfully synthesized from a Sm-containing metal-organic framework (MOF) as a template through a sol-gel reaction and a carbonization process. Carbon 17-23 lysine acetyltransferase 8 Homo sapiens 144-173 31293870-2 2019 An innovative Cu x O/C nanocomposite material, characterized by a highly conductive 3D-framework, with Cu x O/Cu-metal contiguous nanodomains is prepared by electrospinning. Carbon 14-15 cut like homeobox 1 Homo sapiens 103-107 30997950-3 2019 Herein, a surface-confined strategy is developed to restrain SnS2 in self-generated hierarchically porous carbon networks with an in situ reduced graphene oxide (rGO) shell (SnS2 @C@rGO). Carbon 106-112 sodium voltage-gated channel alpha subunit 11 Homo sapiens 61-65 30997950-3 2019 Herein, a surface-confined strategy is developed to restrain SnS2 in self-generated hierarchically porous carbon networks with an in situ reduced graphene oxide (rGO) shell (SnS2 @C@rGO). Carbon 106-112 sodium voltage-gated channel alpha subunit 11 Homo sapiens 174-178 31132280-5 2019 Molecular dynamics simulations of the protein adenine nucleotide translocase (ANT1) and of a carbon nanotube porin in lipid membranes show that the hydrodynamic finite-size correction for rotational diffusion is accurate in standard-use cases. Carbon 93-99 voltage dependent anion channel 1 Homo sapiens 109-114 31141368-9 2019 Its intrinsic NPR, which stems from the weakness of coupling of carbon-carbon bonds, is found upon loading the uniaxial strain along the armchair direction. Carbon 64-70 neuronal pentraxin receptor Homo sapiens 14-17 31141368-9 2019 Its intrinsic NPR, which stems from the weakness of coupling of carbon-carbon bonds, is found upon loading the uniaxial strain along the armchair direction. Carbon 71-77 neuronal pentraxin receptor Homo sapiens 14-17 30955163-4 2019 Moreover, CDP typically consist of carbon cores with a complex mixture of organic chemicals such as polycyclic aromatic hydrocarbons (PAHs) adhered. Carbon 35-41 cut like homeobox 1 Homo sapiens 10-13 31108985-1 2019 A copper sulfide nanoflakes-decorated carbon nanofragments-modified glassy carbon electrode (CuS-CNF/GCE) was fabricated for the electrocatalytic differentiation and determination of hydroquinone (HQ) and catechol (CC). Carbon 38-44 glycine decarboxylase Homo sapiens 93-104 31108985-1 2019 A copper sulfide nanoflakes-decorated carbon nanofragments-modified glassy carbon electrode (CuS-CNF/GCE) was fabricated for the electrocatalytic differentiation and determination of hydroquinone (HQ) and catechol (CC). Carbon 75-81 glycine decarboxylase Homo sapiens 93-104 31139622-3 2019 Here, SnO2-SnS2@C nanoparticles with heterostructure embedded in a carbon matrix of nitrogen-doped graphene (SnO2-SnS2@C/NG) is ingeniously designed in this work. Carbon 67-73 sodium voltage-gated channel alpha subunit 11 Homo sapiens 11-15 31139622-3 2019 Here, SnO2-SnS2@C nanoparticles with heterostructure embedded in a carbon matrix of nitrogen-doped graphene (SnO2-SnS2@C/NG) is ingeniously designed in this work. Carbon 67-73 sodium voltage-gated channel alpha subunit 11 Homo sapiens 114-118 31139622-6 2019 It should be noted that a carbon matrix with nitrogen-doped graphene can inhibit the volume expansion of SnO2-SnS2 nanoparticles and promote the transport of lithium ions during continuous cycling. Carbon 26-32 sodium voltage-gated channel alpha subunit 11 Homo sapiens 110-114 31139622-7 2019 Benefiting from the synergistic effect between nanoparticles and carbon matrix with nitrogen-doped graphene, the heterostructured SnO2-SnS2@C/NG further fundamentally confer improved structural stability and reaction kinetics for lithium storage. Carbon 65-71 sodium voltage-gated channel alpha subunit 11 Homo sapiens 135-139 30927739-3 2019 The synthesized Fe3O4 and carbon-coated Fe3O4 (C/Fe3O4) magnetic nanoparticles were characterized by diverse techniques such as XRD, FESEM, EDX, FTIR, and BET. Carbon 26-32 delta/notch like EGF repeat containing Homo sapiens 155-158 32255129-0 2019 Amorphous carbon modification on implant surface: a general strategy to enhance osteogenic differentiation for diverse biomaterials via FAK/ERK1/2 signaling pathways. Carbon 10-16 mitogen activated protein kinase 3 Rattus norvegicus 140-146 32255129-6 2019 Furthermore, it was demonstrated that the FAK/ERK1/2 signaling pathways were involved in the osteogenic effects of this amorphous carbon coating. Carbon 130-136 mitogen activated protein kinase 3 Rattus norvegicus 46-52 30882199-4 2019 Benefiting from their unique 2D structure and highly exposed active sites, the few-layer NbS2 nanosheets drop-casted on carbon paper exhibited excellent catalytic activity for the hydrogen evolution reaction (HER) in acid with an overpotential of 90 mV at a current density of 10 mA cm-2 and a low Tafel slope of 83 mV dec-1, which are superior to those reported for other NbS2-based HER electrocatalysts. Carbon 120-126 deleted in esophageal cancer 1 Homo sapiens 319-324 30948739-3 2019 We prepared a Co(III) complex and polypyrrole (PPy) composite thin films (CoN4-PPy) that was electrochemically deposited on the surface of a glassy carbon working electrode. Carbon 148-154 pancreatic polypeptide Homo sapiens 47-50 30667570-4 2019 As a proof-of-concept, the Fe-doped carbon electrocatalysts realized a Pt/C-like half-wave potential of 0.869 V vs. RHE and small Tafel slope of 51.3 mV dec-1 in oxygen reduction reaction. Carbon 36-42 deleted in esophageal cancer 1 Homo sapiens 153-158 30960572-5 2019 Different chemical activation methods and temperatures lead to different carbons with BET surface area ranging between 2318 and 2975 m2/g and pore volume up to 1.30 cc/g. Carbon 73-80 delta/notch like EGF repeat containing Homo sapiens 86-89 30918251-2 2019 Here, we report atomically dispersed nickel coordinated with nitrogen and sulfur species in porous carbon nanosheets as an electrocatalyst exhibiting excellent activity and durability for OER with a low overpotential of 1.51 V at 10 mA cm-2 and a small Tafel slope of 45 mV dec-1 in alkaline media. Carbon 99-105 deleted in esophageal cancer 1 Homo sapiens 274-279 30776886-0 2019 Enhanced Lysosomal Escape of pH-Responsive Polyethylenimine-Betaine Functionalized Carbon Nanotube for the Codelivery of Survivin Small Interfering RNA and Doxorubicin. Carbon 83-89 baculoviral IAP repeat-containing 5 Mus musculus 121-129 30776886-3 2019 In this study, a novel pH-responsive, surface-modified single-walled carbon nanotube (SWCNT) was designed for the codelivery of doxorubicin (DOX) and survivin siRNA. Carbon 69-75 baculoviral IAP repeat-containing 5 Mus musculus 150-158 30776886-10 2019 In conclusion, the novel functionalized SWCNT loaded with DOX and survivin siRNA was successfully synthesized, and the nanocomplex exhibited effective antitumor effects both in vitro and in vivo, thereby providing an alternative strategy for the codelivery of antitumor drugs and genes. Carbon 40-45 baculoviral IAP repeat-containing 5 Mus musculus 66-74 30476532-4 2019 Non-cytotoxic doses of carbon nanoparticles but not of bigger carbon particles led to an irreversible reduction of the proliferative capacity accompanied by the accumulation of the cell cycle blocking proteins p21 and p16 as well as a loss of both redox sensitive histone deacetylase SIRT1 and connexin-43. Carbon 23-29 gap junction protein alpha 1 Homo sapiens 294-305 30600818-0 2019 Role of ILK/p38 pathway in mediating the enhanced osteogenic differentiation of bone marrow mesenchymal stem cells on amorphous carbon coating. Carbon 128-134 mitogen activated protein kinase 14 Rattus norvegicus 12-15 30600818-12 2019 Above all, our study indicates that the a-C coating is able to promote osteogenic differentiation of MSCs through the ILK/p38 signaling pathway. Carbon 42-43 mitogen activated protein kinase 14 Rattus norvegicus 122-125 30688319-4 2019 In this work, we find that carbon plays an important synergistic role in improving the performance of La1-xSrxCoO3-delta (0 <= x <= 1) electrocatalysts through the activation of O2 and spillover of radical oxygen intermediates, HO2- and O2-, which is further reduced through chemical decomposition of HO2- on the perovskite surface. Carbon 27-33 heme oxygenase 2 Homo sapiens 234-237 30688319-4 2019 In this work, we find that carbon plays an important synergistic role in improving the performance of La1-xSrxCoO3-delta (0 <= x <= 1) electrocatalysts through the activation of O2 and spillover of radical oxygen intermediates, HO2- and O2-, which is further reduced through chemical decomposition of HO2- on the perovskite surface. Carbon 27-33 heme oxygenase 2 Homo sapiens 307-310 30760492-2 2019 The carbon catabolite repression, mediated by the catabolite control protein A (CcpA), is used to express genes involved in utilization and metabolism of the preferred carbon source. Carbon 4-10 AT695_RS08815 Staphylococcus aureus 50-78 30760492-2 2019 The carbon catabolite repression, mediated by the catabolite control protein A (CcpA), is used to express genes involved in utilization and metabolism of the preferred carbon source. Carbon 4-10 AT695_RS08815 Staphylococcus aureus 80-84 31057777-0 2019 Cu x Ni y alloy nanoparticles embedded in a nitrogen-carbon network for efficient conversion of carbon dioxide. Carbon 53-59 cut like homeobox 1 Homo sapiens 0-4 31057777-3 2019 Here we prepared for the first time Cu x Ni y alloy nanoparticles embedded in a nitrogen-carbon network. Carbon 89-95 cut like homeobox 1 Homo sapiens 36-40 33356092-4 2021 Remarkably, the catalytic activity proves to be highly anion-dependent, with a nearly 10-fold increase toward the aerobic C-C bond cleavage of a lignin model compound when different anionic species are incorporated within the MOF. Carbon 122-123 lysine acetyltransferase 8 Homo sapiens 226-229 30623496-2 2019 Herein, few-layer MoS2 nanosheets, vertically grown on hierarchical carbon nanocages (hCNC) by a facile hydrothermal method, introduce pseudocapacitive lithium storage owing to the highly exposed MoS2 basal planes, enhanced conductivity, and facilitated electrolyte access arising from good hybridization with hCNC. Carbon 68-74 protein kinase cAMP-dependent type I regulatory subunit alpha Homo sapiens 86-90 32830783-6 2019 2NICz (C atom in the 2-position replaced by N) likewise crystallizes in a high-temperature (Pcca, 280 K) polymorph and a low-temperature (P21/c, 150 K) polymorph. Carbon 3-4 propionyl-CoA carboxylase subunit alpha Homo sapiens 92-96 30557826-2 2019 The results showed that hydrothermal assisted pyrolysis carbon with or without activator (HBK and HB) possess higher BET surface area than no hydrothermal assisted carbon (BKs and B, respectively). Carbon 56-62 delta/notch like EGF repeat containing Homo sapiens 117-120 33356092-4 2021 Remarkably, the catalytic activity proves to be highly anion-dependent, with a nearly 10-fold increase toward the aerobic C-C bond cleavage of a lignin model compound when different anionic species are incorporated within the MOF. Carbon 124-125 lysine acetyltransferase 8 Homo sapiens 226-229 33382254-4 2021 Experimentally, we show that high pressure both enhances the adsorption energy of the surfactant sodium dodecylbenzene sulfonate (SDBS) on the SnS2(001) surface at the initial nucleation stage and induces the subsequent oriented attachment (OA) growth of 2D crystallites with monolayer thickness, leading to the formation of a monolayer amorphous carbon-bridged nanosheet mesocrystal. Carbon 347-353 sodium voltage-gated channel alpha subunit 11 Homo sapiens 143-147 30292103-8 2019 These novel porous carbon/MOF composites may have great potential for adsorption application including CO2 capture. Carbon 19-25 lysine acetyltransferase 8 Homo sapiens 26-29 30867454-1 2019 In folate-mediated one-carbon metabolism (FOCM), 5-formyltetrahydrofolate (5fTHF), a one-carbon substituted tetrahydrofolate (THF) vitamer, acts as an intracellular storage form of folate and as an inhibitor of the folate-dependent enzymes phosphoribosylaminoimidazolecarboxamide formyltransferase (AICARFT) and serine hydroxymethyltransferase (SHMT). Carbon 23-29 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Homo sapiens 299-306 30623643-4 2019 Mucin glycoproteins, for example, comprise an abundant source of carbon in the gut, oral cavity, respiratory tract, and other mucosal surfaces but are not commercially available. Carbon 65-71 LOC100508689 Homo sapiens 0-5 33451036-2 2021 The sensor was based on a carbon paste electrode (CPE) modified with electroactive polyimide (EPI) synthesized using aniline tetramer (ACAT) decorated with reduced nanoparticles (NPs) of Au, Pt, and Ag. Carbon 26-32 sterol O-acyltransferase 1 Homo sapiens 135-139 32313843-0 2019 Multi-walled carbon nanotubes inhibit estrogen receptor expression in vivo and in vitro through transforming growth factor beta1. Carbon 13-19 transforming growth factor, beta 1 Mus musculus 96-128 32313843-1 2019 Exposure to multi-walled carbon nanotubes (MWCNTs) is suspected to contribute to pulmonary fibrosis through modulation of transforming growth factor beta1 (TGF-beta1). Carbon 25-31 transforming growth factor, beta 1 Mus musculus 122-154 30606549-2 2019 Then the single-walled carbon nanotubes (SWCNT) were doped with the synthesized Ni(TPA) MOF by the ultrasonic method to improve the chemical stability and the electrochemical activity of the MOF. Carbon 23-29 lysine acetyltransferase 8 Homo sapiens 88-91 30606549-2 2019 Then the single-walled carbon nanotubes (SWCNT) were doped with the synthesized Ni(TPA) MOF by the ultrasonic method to improve the chemical stability and the electrochemical activity of the MOF. Carbon 23-29 lysine acetyltransferase 8 Homo sapiens 191-194 33505412-0 2020 Characterisation of Cellulose Synthase Like F6 (CslF6) Mutants Shows Altered Carbon Metabolism in beta-D-(1,3;1,4)-Glucan Deficient Grain in Brachypodium distachyon. Carbon 77-83 probable mixed-linked glucan synthase 6 Brachypodium distachyon 20-46 30673254-1 2019 Efficient and selective ArS substitution of BODPY by various thiophenols was developed, in which the BODIPYs catalyze the formation of the ArS radicals under light and trap them in situ to form C-S bonds. Carbon 194-195 RIEG2 Homo sapiens 24-27 30673254-1 2019 Efficient and selective ArS substitution of BODPY by various thiophenols was developed, in which the BODIPYs catalyze the formation of the ArS radicals under light and trap them in situ to form C-S bonds. Carbon 194-195 RIEG2 Homo sapiens 139-142 30514726-6 2019 We previously showed that a complex made of Arabidopsis ECERIFERUM1 (CER1) and CER3 catalyzes the conversion of acyl-Coenzyme A"s to alkanes with strict substrate specificity for compounds containing more than 29 carbons. Carbon 213-220 Fatty acid hydroxylase superfamily Arabidopsis thaliana 56-67 30514726-6 2019 We previously showed that a complex made of Arabidopsis ECERIFERUM1 (CER1) and CER3 catalyzes the conversion of acyl-Coenzyme A"s to alkanes with strict substrate specificity for compounds containing more than 29 carbons. Carbon 213-220 Fatty acid hydroxylase superfamily Arabidopsis thaliana 69-73 30514726-6 2019 We previously showed that a complex made of Arabidopsis ECERIFERUM1 (CER1) and CER3 catalyzes the conversion of acyl-Coenzyme A"s to alkanes with strict substrate specificity for compounds containing more than 29 carbons. Carbon 213-220 Fatty acid hydroxylase superfamily Arabidopsis thaliana 79-83 32216238-2 2019 METHODS: Using RT-PCR, we detected the expression of RP1-90L14.1 in LNCaP and LNCaP-AI cells, transiently transfected the RP1-90L14.1 overexpression plasmid (the RP1-90L14.1 group) and vector plasmid (the LNCaP-NC group) into the LNCaP cells, and cultured the two groups of cells with ordinary medium and phenol red-free activated carbon adsorption medium (PRF-ACA). Carbon 331-337 RP1 axonemal microtubule associated Homo sapiens 53-56 33505412-0 2020 Characterisation of Cellulose Synthase Like F6 (CslF6) Mutants Shows Altered Carbon Metabolism in beta-D-(1,3;1,4)-Glucan Deficient Grain in Brachypodium distachyon. Carbon 77-83 probable mixed-linked glucan synthase 6 Brachypodium distachyon 48-53 33505412-8 2020 Together these changes demonstrate an alteration in the carbon storage of cslf6 mutant grains in response to reduced MLG synthase capacity and a possible cross-regulation with starch synthesis which should be a focus in future work in composition of these grains. Carbon 56-62 probable mixed-linked glucan synthase 6 Brachypodium distachyon 74-79 32861946-5 2021 On the rise of the HTT, the carbonaceous structures of biopolymer compositions were reorganized and converted to graphitic structures in biochar accompanied by the large decomposition or carbonization of CEL and HEM, leading to the reduced carbon content, surface functional groups, aromaticity and molecular weight of DBCs, as well as the decrease of protein-like and relative increase of fulvic-like fluorescent substances in most DBCs. Carbon 28-34 huntingtin Homo sapiens 19-22 30873186-0 2019 Phytochrome A Regulates Carbon Flux in Dark Grown Tomato Seedlings. Carbon 24-30 Phytochrome A Solanum lycopersicum 0-13 30873186-4 2019 We profiled proteomic and transcriptomic seedling responses in tomato during the transition from dark to light growth and found that phyA participates in the regulation of carbon flux through major primary metabolic pathways, such as glycolysis, beta-oxidation, and the tricarboxylic acid (TCA) cycle. Carbon 172-178 Phytochrome A Solanum lycopersicum 133-137 30804330-1 2019 Glycine decarboxylase (GLDC) belongs to the glycine cleavage system and is involved in one-carbon metabolism. Carbon 91-97 glycine decarboxylase Homo sapiens 0-21 30664738-4 2019 We show that stimulation with a CpG oligodeoxynucleotide, a Toll-like receptor 9 agonist, evokes changes in the central carbon metabolism of macrophages that enable antitumor activity, including engulfment of CD47+ cancer cells. Carbon 120-126 toll like receptor 9 Homo sapiens 60-80 30804330-1 2019 Glycine decarboxylase (GLDC) belongs to the glycine cleavage system and is involved in one-carbon metabolism. Carbon 91-97 glycine decarboxylase Homo sapiens 23-27 33068589-0 2021 TLR3 inhibitor and tyrosine kinase inhibitor attenuate cigarette smoke/poly I:C-induced airway inflammation and remodeling by the EGFR/TLR3/MAPK signaling pathway. Carbon 78-79 toll like receptor 3 Homo sapiens 0-4 30444729-1 2019 WS2 nanotubes with carbon coatings in a core-shell structure (i.e. WS2@C) are synthesized through a facile method based on the Lewis acid-activated thioglycosylation chemistry. Carbon 19-25 WS2C Homo sapiens 67-72 30444729-2 2019 The obtained WS2@C shows a conformal coverage of conductive amorphous carbon on the surface of WS2 after thermal treatment, with the thickness of carbon layer being controlled by adjusting the molar ratios of saccharide to nanotube during the synthesis process. Carbon 70-76 WS2C Homo sapiens 13-18 30444729-2 2019 The obtained WS2@C shows a conformal coverage of conductive amorphous carbon on the surface of WS2 after thermal treatment, with the thickness of carbon layer being controlled by adjusting the molar ratios of saccharide to nanotube during the synthesis process. Carbon 146-152 WS2C Homo sapiens 13-18 30693767-0 2019 A Novel Carbon Quantum Dots Signal Amplification Strategy Coupled with Sandwich Electrochemiluminescence Immunosensor for the Detection of CA15-3 in Human Serum. Carbon 8-14 mucin 1, cell surface associated Homo sapiens 139-145 33068589-0 2021 TLR3 inhibitor and tyrosine kinase inhibitor attenuate cigarette smoke/poly I:C-induced airway inflammation and remodeling by the EGFR/TLR3/MAPK signaling pathway. Carbon 78-79 toll like receptor 3 Homo sapiens 135-139 30693767-1 2019 A sensitive sandwich electrochemiluminescence immunosensor was established by employing graphene oxide-PEI-carbon quantum dots (CQDs)-Au nanohybrid as probe to measure carbohydrate antigen 15-3 (CA15-3), a breast cancer biomarker. Carbon 107-113 mucin 1, cell surface associated Homo sapiens 160-201 33218895-5 2021 Molecular modeling studies demonstrated that inhibitory activity was strictly dependent on the formation of a Michaelis complex between the OH group of HNE Ser195 and the carbonyl carbon of the inhibitor. Carbon 171-177 elastase, neutrophil expressed Homo sapiens 152-155 32313843-1 2019 Exposure to multi-walled carbon nanotubes (MWCNTs) is suspected to contribute to pulmonary fibrosis through modulation of transforming growth factor beta1 (TGF-beta1). Carbon 25-31 transforming growth factor, beta 1 Mus musculus 156-165 30556651-3 2019 To determine the global metabolic impact of UCP2 upregulation, 13 C6 glucose as a source molecule is used to "trace" the metabolic fate of carbon atoms derived from glucose. Carbon 139-145 uncoupling protein 2 Homo sapiens 44-48 30534769-2 2019 Herein, flower-like SnS2 anchored on 3D carbon nanofiber structures were designed and synthesized by a simple hydrothermal method. Carbon 40-46 sodium voltage-gated channel alpha subunit 11 Homo sapiens 20-24 30534769-3 2019 Pyrolyzed bacterial cellulose as 3D carbon nanofibers can not only offer a continuous pathway of Li+ and electrons, but can also migrate the serious volume change of SnS2 during charging and discharging. Carbon 36-42 sodium voltage-gated channel alpha subunit 11 Homo sapiens 166-170 33156984-0 2021 Black Carbon Content in Airway Macrophages is Associated with Reduced CD80 Expression and Increased Exacerbations in Former Smokers With COPD. Carbon 6-12 CD80 molecule Homo sapiens 70-74 30886796-2 2019 Here, a sacrificial-counter-electrode method to synthesize a MoS x /carbon nanotubes/Pt catalyst (0.55 wt% Pt loading) is developed, which exhibits a low overpotential of 25 mV at a current density of 10 mA cm-2, a low Tafel slope of 27 mV dec-1, and excellent stability under acidic conditions. Carbon 68-74 deleted in esophageal cancer 1 Homo sapiens 240-245 30274713-2 2019 Specifically, SPL catalyzes the cleavage of sphingosine 1-phosphate (S1P) at the C2-3 carbon bond, resulting in its irreversible degradation to phosphoethanolamine (PE) and hexadecenal. Carbon 86-92 sphingosine-1-phosphate lyase 1 Homo sapiens 14-17 30408958-0 2019 MitoTarget Modeling Using ANN-Classification Models Based on Fractal SEM Nano-Descriptors: Carbon Nanotubes as Mitochondrial F0F1-ATPase Inhibitors. Carbon 91-97 ATP synthase F1 subunit epsilon Homo sapiens 125-136 33156984-10 2021 Higher AM black carbon content was associated with increased total exacerbations and severe exacerbations and reduced CD80 expression. Carbon 16-22 CD80 molecule Homo sapiens 118-122 32436837-8 2021 The most important changes occurred in the HIF1alpha and NF-KB signaling pathways targeted genes and in central carbon metabolism pathway genes such as HKs, PFKL, and solute transporters. Carbon 112-118 phosphofructokinase, liver type Homo sapiens 157-161 30660106-1 2019 We report here a supercatalyst for oxygen reduction of Pt/CNx/Ni in a unique ternary heterostructure, in which the Pt and the underlying Ni nanoparticles are separated by two to three layers of nitrogen-doped carbon (CNx), which mediates the transfer of electrons from the inner Ni to the outer Pt and protects the Ni against corrosion at the same time. Carbon 209-215 calnexin Homo sapiens 58-61 31628657-3 2019 GSDMD contains a functionally important N-terminal domain (GSDMD-N), a C-terminal domain, and a linker in between that is recognized and cleaved by the activated inflammatory caspases. Carbon 71-72 gasdermin D Homo sapiens 0-5 33383149-8 2021 The rIL-33 pre-treated mice in both Poly I:C and ConA challenge groups showed significantly (P <= 0.05) lower levels of AST and ALT, and decreased liver injury (parenchymal and per-vascular necrotic areas) in histological liver sections. Carbon 43-44 interleukin 33 Rattus norvegicus 4-10 33387195-5 2021 RFLS was stimulated with Toll-like receptor 3 (TLR3) ligand polyinosinic:polycytidylic acid (poly I:C), a synthetic double-stranded RNA mimetic. Carbon 100-101 toll like receptor 3 Homo sapiens 25-45 30412832-7 2019 Structure-activity relationship analyses and molecular docking simulations demonstrated that the bridge of two-carbon atoms between the C-4 position of the triazole and the phenyl ring (6a), which may be replaced by heteroatoms such as N (6k) or O (6l), is fundamental for accommodation and inhibition within OGA catalytic pocket. Carbon 111-117 O-GlcNAcase Homo sapiens 309-312 30528455-9 2019 Functionally, induction of ARG1 limited the therapeutic effect of IFN, as inhibition of arginase activity could strongly synergize with poly(I:C) to enhance CD8+ T cell responses to thwart tumor growth in mice. Carbon 143-144 arginase, liver Mus musculus 27-31 30692937-1 2018 When fasted as larvae or fed ketogenic diets as adults, homozygous zebrafish slc16a6a mutants develop hepatic steatosis because their livers cannot export the major ketone body beta-hydroxybutyrate, diverting liver-trapped ketogenic carbon atoms to triacylglycerol. Carbon 233-239 solute carrier family 16 member 6a Danio rerio 77-85 30609921-4 2019 Although overexpression of CeGNA1 drove carbon flux from pyruvate to the GlcNAc synthesis pathway and decreased pyruvate accumulation, the residual pyruvate reduced the intracellular pH, resulting in inhibited CeGNA1 activity and limited GlcNAc production. Carbon 40-46 Glucosamine 6-phosphate N-acetyltransferase Caenorhabditis elegans 27-33 33387195-5 2021 RFLS was stimulated with Toll-like receptor 3 (TLR3) ligand polyinosinic:polycytidylic acid (poly I:C), a synthetic double-stranded RNA mimetic. Carbon 100-101 toll like receptor 3 Homo sapiens 47-51 33325677-0 2020 Highly Aligned Carbon Nanowire Array by E-Field Directed Assembly of PAN-Containing Block Copolymers. Carbon 15-21 adenosine deaminase 2 Homo sapiens 69-72 31930204-5 2019 A member of the ELL family (ELL1) was recently proven to act as an E3 ubiquitin ligase to known proto-oncogene, c-Myc, through a highly conserved cysteine residue in the C-terminal CEYLH region. Carbon 170-171 elongation factor for RNA polymerase II Homo sapiens 28-32 29689347-9 2019 DI-C-RAMP2-/- hearts also showed changes in mitochondrial structure and downregulation of mitochondria-related genes involved in oxidative phosphorylation and beta-oxidation. Carbon 3-4 receptor (calcitonin) activity modifying protein 2 Mus musculus 5-10 33325677-4 2020 Lithographic patterning of the graphene electrode as well as straightforward thermal carbonization of the PAN block creates well-aligned carbon nanowire device structures. Carbon 85-91 adenosine deaminase 2 Homo sapiens 106-109 30340996-6 2018 The nanoESI MS analysis of neuraminic acids after treatment of BSM with NanS-p gave evidence that NanS-p variants of EHEC O157:H7 strain EDL933 cleave off O-acetyl groups from mono-, di-, and tri-O-acetylated Neu5Ac and N-glycolylneuraminic acid (Neu5Gc), regardless of the carbon positions C7, C8 or C9 of the acetate esters. Carbon 274-280 N-acetylneuraminate synthase Bos taurus 72-76 30340996-6 2018 The nanoESI MS analysis of neuraminic acids after treatment of BSM with NanS-p gave evidence that NanS-p variants of EHEC O157:H7 strain EDL933 cleave off O-acetyl groups from mono-, di-, and tri-O-acetylated Neu5Ac and N-glycolylneuraminic acid (Neu5Gc), regardless of the carbon positions C7, C8 or C9 of the acetate esters. Carbon 274-280 N-acetylneuraminate synthase Bos taurus 98-102 30599734-2 2018 The present study focuses on MVK-oxide, a four-carbon unsaturated carbonyl oxide intermediate, using vacuum ultraviolet photoionization at 118 nm and UV-visible induced depletion of the m/z = 86 mass channel to characterize its first pi* pi electronic transition. Carbon 47-53 mevalonate kinase Homo sapiens 29-32 32979721-0 2020 Granular activated carbon-supported titanium dioxide nanoparticles as an amendment for amending copper-contaminated sediments: Effect on the pH in sediments and enzymatic activities. Carbon 19-25 phenylalanine hydroxylase Homo sapiens 141-143 30596388-0 2018 Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube (SWCNT)-delivered MALAT1 Antisense Oligos. Carbon 66-72 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 100-106 30445257-2 2018 Recently, we have discovered the NF-kappaB pathway activated by TLR3 is involved in apoptosis of UVB-Poly I:C-treated HaCaT cells. Carbon 108-109 toll like receptor 3 Homo sapiens 64-68 33010592-9 2020 Our results indicate a significant effect of Ag2S NPs on SBC, specifically on parameters related to carbon and phosphorous cycling, at doses as low as 10 mg kg-1 soil. Carbon 100-106 angiotensin II receptor type 1 Homo sapiens 45-49 30509587-9 2018 The Raman, DT/TGA and XRD analyses on spent catalysts revealed the deposited carbon during steam reforming of tar reaction is majorly amorphous. Carbon 77-83 T-box transcription factor 1 Homo sapiens 14-17 30406794-5 2018 The few graphitic carbon layer-encapsulated nanoparticles with the main W2C phase prepared by this simple method exhibit high efficiency for hydrogen generation with a low overpotential of 240 mV at a current density of 10 mA cm-2 and a low Tafel slope of 86 mV dec-1. Carbon 18-24 deleted in esophageal cancer 1 Homo sapiens 262-267 30251372-8 2018 Cdc31 and cdc31 mutant proteins showed distinct interactions with proteins in energy metabolism, and mutants showed sensitivity to oxidative stress and poor growth on non-fermentable carbon. Carbon 183-189 centrin Saccharomyces cerevisiae S288C 0-5 30740289-3 2019 Upon modifying the ancillary ligands, or proceeding along the catalytic cycle, hapticity changes can be observed; it varies from eta5, if the five metal-carbon distances are identical, through eta3+eta2, in the presence of allylic distortion, and eta3, in the case of allylic coordination, to eta1, if a sigma metal-carbon bond forms. Carbon 316-322 DNA polymerase iota Homo sapiens 198-202 32823226-0 2020 Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids. Carbon 13-19 nitric oxide synthase 1 Homo sapiens 39-59 29986579-4 2018 In this study, we investigated the influence of hydroxylated single-walled carbon nanotubes (SWCNT-OHs) on the first step of hIAPP aggregation: dimerization by performing explicit solvent replica exchange molecular dynamics (REMD) simulations. Carbon 75-81 islet amyloid polypeptide Homo sapiens 125-130 31950726-0 2018 Thermal Conversion of MOF@MOF: Synthesis of an N-Doped Carbon Material with Excellent ORR Performance. Carbon 55-61 lysine acetyltransferase 8 Homo sapiens 22-29 30251372-8 2018 Cdc31 and cdc31 mutant proteins showed distinct interactions with proteins in energy metabolism, and mutants showed sensitivity to oxidative stress and poor growth on non-fermentable carbon. Carbon 183-189 centrin Saccharomyces cerevisiae S288C 10-15 32823226-1 2020 Multi-walled carbon nanotubes (MWCNTs) might induce the dysfunction of neuronal NO synthase (nNOS) and impair the function of brains. Carbon 13-19 nitric oxide synthase 1 Homo sapiens 71-91 30080574-5 2018 The electrochemical studies show that the GL-VS2 modified glassy carbon electrode (GL-VS2/GCE) has a superior electrocatalytic activity and lower-reduction potential than the response observed for unmodified GCE. Carbon 65-71 glycine cleavage system protein H Homo sapiens 83-93 32823226-1 2020 Multi-walled carbon nanotubes (MWCNTs) might induce the dysfunction of neuronal NO synthase (nNOS) and impair the function of brains. Carbon 13-19 nitric oxide synthase 1 Homo sapiens 93-97 30080574-5 2018 The electrochemical studies show that the GL-VS2 modified glassy carbon electrode (GL-VS2/GCE) has a superior electrocatalytic activity and lower-reduction potential than the response observed for unmodified GCE. Carbon 65-71 glycine cleavage system protein H Homo sapiens 90-93 30005266-0 2018 Spatial variability of on-bicycle black carbon concentrations in the megacity of Sao Paulo: A pilot study. Carbon 40-46 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 81-84 33237716-0 2020 On the Origin of the Effect of pH in Oxygen Reduction Reaction for Nondoped and Edge-Type Quaternary N-Doped Metal-Free Carbon-Based Catalysts. Carbon 120-126 phenylalanine hydroxylase Homo sapiens 31-33 29920443-6 2018 The as-prepared carbon nanobowls supported ultrafine iridium nanocrystals present an ultra-low overpotential of 290 mV to achieve the mass activity of 1000 A g-1 and a small Tafel slope of 49.1 mV dec-1, which significantly outperform commercial Ir/C electrocatalyst. Carbon 16-22 deleted in esophageal cancer 1 Homo sapiens 197-202 30155930-4 2018 For derivates of Ni, Co and Mn-MOFs, graphitized carbons (GCs) show some carbon graphitization, but their BET specific surface areas are relatively small. Carbon 49-56 delta/notch like EGF repeat containing Homo sapiens 106-109 30155930-3 2018 Zn and Cd-MOFs lead to the derivation of porous carbons (PCs), which exhibit remarkable BET specific surface areas. Carbon 48-55 delta/notch like EGF repeat containing Homo sapiens 88-91 33237716-6 2020 We address this matter through a combined experimental and modeling study, which yields fundamental principles on the origin of the pH effects in ORR for carbon-based materials. Carbon 154-160 phenylalanine hydroxylase Homo sapiens 132-134 30155930-5 2018 C-Cu has the smallest BET specific surface area, and there is no carbon graphitization. Carbon 0-1 delta/notch like EGF repeat containing Homo sapiens 22-25 33237716-7 2020 This is relevant for the design of pH-independent metal-free carbon-based catalysts. Carbon 61-67 phenylalanine hydroxylase Homo sapiens 35-37 33425736-8 2020 Notably, our study allows us to suggest that miR-3143 regulates the carbon metabolism by targeting hexokinase-2. Carbon 68-74 hexokinase 2 Homo sapiens 99-111 30152580-2 2018 This deficit has resulted in a short supply of beta2, 2 -amino acids bearing two substituents at the alpha-carbon, especially for peptide synthesis. Carbon 107-113 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 47-55 30355296-10 2018 We searched for additional genes associated with a PhaR-binding sequence and found that some genes involved in central carbon metabolism, such as pdhA for pyruvate dehydrogenase and pckA for phosphoenolpyruvate carboxykinase, may be regulated positively and directly by PhaR. Carbon 119-125 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha Bradyrhizobium diazoefficiens USDA 110 146-150 30355296-10 2018 We searched for additional genes associated with a PhaR-binding sequence and found that some genes involved in central carbon metabolism, such as pdhA for pyruvate dehydrogenase and pckA for phosphoenolpyruvate carboxykinase, may be regulated positively and directly by PhaR. Carbon 119-125 phosphoenolpyruvate carboxykinase Bradyrhizobium diazoefficiens USDA 110 191-224 33415004-0 2020 Molecular mechanisms underlying the enhancement of carbon ion beam radiosensitivity of osteosarcoma cells by miR-29b. Carbon 51-57 microRNA 29b-1 Homo sapiens 109-116 30369913-5 2018 Comparative analysis of the genes involved in carbon, nitrogen and sulfur metabolisms revealed that heterotrophic processes (i.e., degradation of carbohydrates, hydrocarbons, and aromatics) are the most common microbial metabolisms in the seawater, while chemolithoautotrophic metabolisms such as ammonia oxidation with the HP/HB cycle for CO2 fixation probably dominated the surface sediment communities of the Yap Trench. Carbon 46-52 Yes1 associated transcriptional regulator Homo sapiens 412-415 33415004-8 2020 When used in combination with miR-29b mimic, carbon ion beam markedly inhibited invasion, migration, and proliferation of OSA cells and promoted apoptosis by inhibiting AKT phosphorylation in a Sp1/PTEN-mediated manner. Carbon 45-51 microRNA 29b-1 Homo sapiens 30-37 33415004-9 2020 Taken together, miR-29b mimic improved the radiosensitivity of OSA cells via the PTEN-AKT-Sp1 signaling pathway, presenting a novel strategy for the development of carbon ion beam combination therapy. Carbon 164-170 microRNA 29b-1 Homo sapiens 16-23 30339427-0 2018 Unambiguous Identification of Carbon Location on the N Site in Semi-insulating GaN. Carbon 30-36 gigaxonin Homo sapiens 79-82 30203647-10 2018 This five-carbon metabolite feeds into three separate essential pathways for bacterial central metabolism: ThDP synthesis, pyridoxal phosphate (PLP) synthesis, and the MEP pathway for isoprenoid synthesis. Carbon 10-16 pyridoxal phosphatase Homo sapiens 144-147 33266291-4 2020 Serine hydroxymethyltransferase (SHMT) is indispensable for the one-carbon metabolism of serine/glycine interconversion and is linked to folate metabolism. Carbon 68-74 AT695_RS06945 Staphylococcus aureus 0-31 30339427-1 2018 Carbon (C) doping is essential for producing semi-insulating GaN for power electronics. Carbon 0-6 gigaxonin Homo sapiens 61-64 30215504-9 2018 The P-O bond in carbon prevents the permeation and decomposition of solvated PF6- in the interior of the electrode during cycling, resulting in the improved ICE, reversible capacity, and rate capability. Carbon 16-22 sperm associated antigen 17 Homo sapiens 77-80 32254719-0 2018 Membrane and nucleus targeting for highly sensitive cancer cell detection using pyrophosphate and alkaline phosphatase activity-mediated fluorescence switching of functionalized carbon dots. Carbon 178-184 alkaline phosphatase, biomineralization associated Canis lupus familiaris 98-118 30062480-7 2018 This enzyme cascade of two subsequent C-C bond formations (EDA aldolase and a ThDP-dependent carboligase, MenD) generates two new stereocenters. Carbon 38-39 ectodysplasin A Homo sapiens 59-62 33266291-4 2020 Serine hydroxymethyltransferase (SHMT) is indispensable for the one-carbon metabolism of serine/glycine interconversion and is linked to folate metabolism. Carbon 68-74 AT695_RS06945 Staphylococcus aureus 33-37 33213020-1 2020 The paper reports the synthesis of carbon nanotubes from ethanol over group VIII (Fe, Co, Ni) catalysts derived from corresponding metallocenes. Carbon 35-41 cytochrome c oxidase subunit 8A Homo sapiens 76-80 29632340-7 2018 Furthermore, using novel single-wall carbon nanotube (SWCNT) conjugated with anti-MALAT1 oligos, we successfully knocked-down MALAT1 RNA in cultured MM cell lines and xenograft murine models. Carbon 37-43 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) Mus musculus 126-132 29873416-6 2018 Using cell-based studies, we also establish that EWS cells are dependent on glutamine for cell survival and that EWS-FLI1 positively regulates expression of the glutamine transporter, SLC1A5 and two enzymes involved in the one-carbon cycle, MTHFD2 and MTHFD1L. Carbon 227-233 EWS RNA binding protein 1 Homo sapiens 113-116 29873416-6 2018 Using cell-based studies, we also establish that EWS cells are dependent on glutamine for cell survival and that EWS-FLI1 positively regulates expression of the glutamine transporter, SLC1A5 and two enzymes involved in the one-carbon cycle, MTHFD2 and MTHFD1L. Carbon 227-233 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Homo sapiens 252-259 32512434-6 2020 Evaluation of KSS data for the 4 h extractions showed that soil type and selected HMW-PAH properties (literature based molecular weight and octanol-carbon partition coefficients) affect the amount of HMW-PAH released from soil into sebum. Carbon 148-154 cilia and flagella associated protein 97 Homo sapiens 82-85 30363688-8 2018 Loss-of-function studies found that SMAD3 knockdown in myometrial cells significantly increased IL-1beta- and poly(I : C)-induced proinflammatory cytokines (IL-1A, IL-6), chemokines (IL-8, MCP-1), the adhesion molecule ICAM-1, COX-2 mRNA expression, and subsequent PGF2alpha release. Carbon 119-120 SMAD family member 3 Homo sapiens 36-41 33158046-8 2020 Thus, CUE1 regulates NO homeostasis during post-germinative growth to modulate root development in response to carbon metabolism, as different sugars modify root elongation and meristem organization in cue1 mutants. Carbon 111-117 Glucose-6-phosphate/phosphate translocator-like protein Arabidopsis thaliana 6-10 30568779-0 2018 Cobalt-based nanoparticles prepared from MOF-carbon templates as efficient hydrogenation catalysts. Carbon 45-51 lysine acetyltransferase 8 Homo sapiens 41-44 30091504-3 2018 Building on our previous report of C-Br-selective functionalization in the presence of C-OTf and C-Cl bonds, we herein complete the sequence and demonstrate the first general arylations and alkylations of C-OTf bonds (in <10 min), followed by functionalization of the C-Cl site (in <25 min), at room temperature using the same air- and moisture-stable PdI dimer. Carbon 35-36 prolyl 4-hydroxylase subunit beta Homo sapiens 358-361 33158046-8 2020 Thus, CUE1 regulates NO homeostasis during post-germinative growth to modulate root development in response to carbon metabolism, as different sugars modify root elongation and meristem organization in cue1 mutants. Carbon 111-117 Glucose-6-phosphate/phosphate translocator-like protein Arabidopsis thaliana 202-206 30004225-3 2018 Enantiomerically pure C, N-unprotected beta2-AAs could be obtained by simple hydrolysis of an isolated favored Ni(II) complex. Carbon 22-23 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 39-44 30568779-3 2018 Herein, we report the preparation of graphene shell encapsulated Co3O4- and Co-nanoparticles supported on carbon by the template synthesis of cobalt-terephthalic acid MOF on carbon and subsequent pyrolysis. Carbon 106-112 lysine acetyltransferase 8 Homo sapiens 167-170 30568779-3 2018 Herein, we report the preparation of graphene shell encapsulated Co3O4- and Co-nanoparticles supported on carbon by the template synthesis of cobalt-terephthalic acid MOF on carbon and subsequent pyrolysis. Carbon 174-180 lysine acetyltransferase 8 Homo sapiens 167-170 31787028-0 2020 Computational investigation reveals Picrasidine C as selective PPARalpha lead: binding pattern, selectivity mechanism and ADME/Tox profile. Carbon 36-49 thymocyte selection associated high mobility group box Homo sapiens 127-130 30149914-2 2018 The present study elucidated the involvement of pro-inflammatory cytokines, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in carboxylated multi-walled carbon nanotubes (MWCNTs)-induced hepatotoxicity. Carbon 173-179 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 76-92 30149914-2 2018 The present study elucidated the involvement of pro-inflammatory cytokines, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in carboxylated multi-walled carbon nanotubes (MWCNTs)-induced hepatotoxicity. Carbon 173-179 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 94-99 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 227-240 thymocyte selection associated high mobility group box Homo sapiens 954-957 32936395-8 2020 The TLR3 p.L742F allele displayed low poly(I:C)-stimulated cytokine induction when expressed in P2.1 cells. Carbon 45-47 toll like receptor 3 Homo sapiens 4-8 29908158-2 2018 In this sandwich type immunoassay, CA15-3 antibody-functionalized carbon dots and AuNPs labeled PAMAM-Dendrimer/aptamer were used as donor/acceptor, respectively. Carbon 66-72 mucin 1, cell surface associated Homo sapiens 35-41 32948893-4 2020 In contrast, Snf1 is inactive when preferred carbon sources are available, which leads to dephosphorylation of Mig1 and its translocation to the nucleus where Mig1 acts as a transcription repressor. Carbon 45-51 transcription factor MIG1 Saccharomyces cerevisiae S288C 111-115 29908158-3 2018 When CA 15-3 Ag was added to homogenous immunoassay, the strong complex interaction between CA15-3 Ab-CA15-3 Ag- aptamer caused in more coming closer carbon dot and AuNPs and more decreasing fluorescence signal. Carbon 150-156 mucin 1, cell surface associated Homo sapiens 92-98 29908158-3 2018 When CA 15-3 Ag was added to homogenous immunoassay, the strong complex interaction between CA15-3 Ab-CA15-3 Ag- aptamer caused in more coming closer carbon dot and AuNPs and more decreasing fluorescence signal. Carbon 150-156 mucin 1, cell surface associated Homo sapiens 102-108 30004225-1 2018 We report the first purely chemical method for the resolution of C, N-unprotected racemic alpha-substituted beta-amino acids (beta2-AAs) using thermodynamically stable and recyclable chiral proline-derived ligands. Carbon 65-67 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 126-131 32948893-4 2020 In contrast, Snf1 is inactive when preferred carbon sources are available, which leads to dephosphorylation of Mig1 and its translocation to the nucleus where Mig1 acts as a transcription repressor. Carbon 45-51 transcription factor MIG1 Saccharomyces cerevisiae S288C 159-163 32917772-2 2020 Arabidopsis thaliana mutants lacking f-type Trxs (trx f1f2) show delayed activation of carbon assimilation due to impaired photoreduction of Calvin-Benson cycle enzymes. Carbon 87-93 thioredoxin H-type 1 Arabidopsis thaliana 50-53 29667516-1 2018 In this study, MnO2 and pyrolusite were used as the catalysts to prepare modified activated carbon, that is, AC-Mn and AC-P, respectively, from coals by blending method and steam activation. Carbon 92-98 NADH:ubiquinone oxidoreductase subunit AB1 Homo sapiens 119-123 29667516-3 2018 The relative contents of basic functional groups (i.e., C = O, pi-pi*) on AC-P were slightly lower than those on AC-Mn, while both contained the same main metal species, namely, MnO. Carbon 56-57 NADH:ubiquinone oxidoreductase subunit AB1 Homo sapiens 74-78 29667516-8 2018 IMPLICATIONS: MnO2 and pyrolusite were used as the additives to prepare modified activated carbon from coals by a blending method and by steam activation, that is, AC-Mn and AC-P, respectively. Carbon 91-97 NADH:ubiquinone oxidoreductase subunit AB1 Homo sapiens 174-178 33121290-10 2021 NOB + Poly I:C could improve the activation of TLR3/IRF3 signaling pathway. Carbon 13-14 toll like receptor 3 Homo sapiens 47-51 29947767-0 2018 High linear energy transfer carbon-ion irradiation increases the release of the immune mediator high mobility group box 1 from human cancer cells. Carbon 28-34 high mobility group box 1 Homo sapiens 96-121 33121290-10 2021 NOB + Poly I:C could improve the activation of TLR3/IRF3 signaling pathway. Carbon 13-14 interferon regulatory factor 3 Homo sapiens 52-56 33085544-1 2020 The carbon catabolite repressor 4-negative on TATA (CCR4-NOT) complex, abbreviated CNOT, has deadenylation and 3"-5" exonuclease activity, mediates deadenylation in the degradation of RNA, initiates the exonuclease degradation pathway, and participates in tumor gene regulation. Carbon 4-10 C-C motif chemokine receptor 4 Homo sapiens 52-56 30024025-2 2018 Folate metabolism, which requires the enzyme methionine synthase reductase (MTRR), is necessary for DNA synthesis and the transmission of one-carbon methyl groups for cellular methylation. Carbon 142-148 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Mus musculus 45-74 30024025-2 2018 Folate metabolism, which requires the enzyme methionine synthase reductase (MTRR), is necessary for DNA synthesis and the transmission of one-carbon methyl groups for cellular methylation. Carbon 142-148 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Mus musculus 76-80 33086514-5 2020 All the results suggested that the carbon hexagonal network plane of graphite surfaces have a high potential to facilitate the clustering of fat molecules against high thermal fluctuations in fat melt, the fat molecules form a layer structure parallel to the graphite surface, and the clusters tend to grow into thin plate crystals of the beta phase at the temperatures corresponding to low supercooling. Carbon 35-41 FAT atypical cadherin 1 Homo sapiens 141-144 30059618-0 2018 Inverse Capacity Growth and Pocket Effect in SnS2 Semifilled Carbon Nanotube Anode. Carbon 61-67 sodium voltage-gated channel alpha subunit 11 Homo sapiens 45-49 30059618-2 2018 A nanostructure of the SnS2 semifilled carbon nanotube (SnS2@CNT) has been realized by plasma-assisted fabrication of Sn semifilled CNT (Sn@CNT) followed by post-sulfurization. Carbon 39-45 sodium voltage-gated channel alpha subunit 11 Homo sapiens 23-27 30059618-2 2018 A nanostructure of the SnS2 semifilled carbon nanotube (SnS2@CNT) has been realized by plasma-assisted fabrication of Sn semifilled CNT (Sn@CNT) followed by post-sulfurization. Carbon 39-45 sodium voltage-gated channel alpha subunit 11 Homo sapiens 56-60 33086514-5 2020 All the results suggested that the carbon hexagonal network plane of graphite surfaces have a high potential to facilitate the clustering of fat molecules against high thermal fluctuations in fat melt, the fat molecules form a layer structure parallel to the graphite surface, and the clusters tend to grow into thin plate crystals of the beta phase at the temperatures corresponding to low supercooling. Carbon 35-41 FAT atypical cadherin 1 Homo sapiens 192-195 33086514-5 2020 All the results suggested that the carbon hexagonal network plane of graphite surfaces have a high potential to facilitate the clustering of fat molecules against high thermal fluctuations in fat melt, the fat molecules form a layer structure parallel to the graphite surface, and the clusters tend to grow into thin plate crystals of the beta phase at the temperatures corresponding to low supercooling. Carbon 35-41 FAT atypical cadherin 1 Homo sapiens 192-195 29654607-3 2018 We incorporated a representation of HR into the Community Land Model (CLM4.5) and found the new model improved predictions of water, energy, and system-scale carbon fluxes observed by eddy covariance at four seasonally dry yet ecologically diverse temperate and tropical AmeriFlux sites. Carbon 158-164 CD300 molecule like family member d Homo sapiens 70-74 32588534-3 2020 Here, we synthesize a pair of hollow carbon sphere (HCS) nanoreactors with pre-synthesized PdCu nanoparticles encapsulated inside of HCS (PdCu@HCS) and supported outside of HCS (PdCu/HCS), respectively, while keeping other structural features the same. Carbon 37-43 holocarboxylase synthetase Homo sapiens 52-55 32643319-7 2020 We find a quasi-Mars-van-Krevelen (quasi-MvK) surface reaction mechanism involving extracting and refilling the surface carbon atoms for the nonoxidative conversion of methane on Fe 1 SiO 2 and this new surface process is identified to be more plausible than the alternative gas-phase reaction mechanism. Carbon 120-126 mevalonate kinase Homo sapiens 41-44 29742950-0 2018 Inflammation in the pleural cavity following injection of multi-walled carbon nanotubes is dependent on their characteristics and the presence of IL-1 genes. Carbon 71-77 interleukin 1 complex Mus musculus 146-150 32989163-8 2020 This work provides a fundamental biochemical rationale for nonredundant roles of these RNA demethylases beyond different substrate preferences and cellular localization, where m6A demethylation by ALKBH5 versus FTO results in release of FA, an endogenous one-carbon unit but potential genotoxin, at different rates in living systems. Carbon 259-265 alkB homolog 5, RNA demethylase Homo sapiens 197-203 30008872-5 2018 Subsequently, the expression of the one-carbon metabolic enzymes methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), aldehyde dehydrogenase 1 family member L2 (ALDH1L2), and serine hydroxymethyltransferase (SHMT2) was examined using immunohistochemical analysis. Carbon 40-46 aldehyde dehydrogenase 1 family member L2 Homo sapiens 117-158 30008872-5 2018 Subsequently, the expression of the one-carbon metabolic enzymes methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), aldehyde dehydrogenase 1 family member L2 (ALDH1L2), and serine hydroxymethyltransferase (SHMT2) was examined using immunohistochemical analysis. Carbon 40-46 aldehyde dehydrogenase 1 family member L2 Homo sapiens 160-167 32052226-5 2020 Here, we have shown that bicuculline induced GluA2 ubiquitination on the same lysine residues (Lys-870 and Lys-882) in the C-terminal as those elicited by the AMPA treatment. Carbon 123-124 glutamate ionotropic receptor AMPA type subunit 2 Homo sapiens 45-50 29946611-8 2018 This observed hydroxylation reactivity is consistent with the postulated first step of Mo-Cu CODH (nucleophilic attack of the Mo(vi)-oxo on the Cu(i)-bound electrophilic CO) and xanthine oxidoreductase (nucleophilic attack of Mo(vi)-oxo on the electrophilic xanthine carbon). Carbon 267-273 xanthine dehydrogenase Homo sapiens 178-201 32052226-7 2020 Pharmacological activation of protein kinase C (PKC) by phorbol ester, which mediates the phosphorylation of GluA2 at Ser-880, augmented bicuculline-induced ubiquitination of GluA2 in cultured neurons. Carbon 45-46 glutamate ionotropic receptor AMPA type subunit 2 Homo sapiens 109-114 32052226-7 2020 Pharmacological activation of protein kinase C (PKC) by phorbol ester, which mediates the phosphorylation of GluA2 at Ser-880, augmented bicuculline-induced ubiquitination of GluA2 in cultured neurons. Carbon 45-46 glutamate ionotropic receptor AMPA type subunit 2 Homo sapiens 175-180 32816359-9 2020 Appreciating the contributions of Forest Transitions to the sequestering of atmospheric carbon will enable its potential to aid in climate change mitigation. Carbon 88-94 activation induced cytidine deaminase Homo sapiens 124-127 29769197-6 2018 CAFs were more efficient than HNSCC in using lactate as a carbon source. Carbon 58-64 T-box transcription factor 1 Homo sapiens 0-4 29442644-5 2018 The pyrolysis of Fe-MOF with the largest amount of mesopores resulted in its carbonization and produced gamma-Fe2O3@carbon material, significantly reduced the BET surface area from 3036 m2 g-1 to 387 m2 g-1, but increased the average pore diameter up to 5.78 nm and disintegrated their octahedral structures to an irregular morphology of Fe-MOF (550), and modified the carbon matrix with trace oxygen and metal oxides. Carbon 77-83 lysine acetyltransferase 8 Homo sapiens 20-23 32799169-8 2020 Therefore, NSP1 of PRRSV-2 inhibited the mRNA transcription of ccn1 and ccn2 by blocking the ERK-AP-1 axis in Poly I:C stimulated pig macrophages. Carbon 117-118 cellular communication network factor 2 Homo sapiens 72-76 29442644-5 2018 The pyrolysis of Fe-MOF with the largest amount of mesopores resulted in its carbonization and produced gamma-Fe2O3@carbon material, significantly reduced the BET surface area from 3036 m2 g-1 to 387 m2 g-1, but increased the average pore diameter up to 5.78 nm and disintegrated their octahedral structures to an irregular morphology of Fe-MOF (550), and modified the carbon matrix with trace oxygen and metal oxides. Carbon 116-122 lysine acetyltransferase 8 Homo sapiens 20-23 29442644-5 2018 The pyrolysis of Fe-MOF with the largest amount of mesopores resulted in its carbonization and produced gamma-Fe2O3@carbon material, significantly reduced the BET surface area from 3036 m2 g-1 to 387 m2 g-1, but increased the average pore diameter up to 5.78 nm and disintegrated their octahedral structures to an irregular morphology of Fe-MOF (550), and modified the carbon matrix with trace oxygen and metal oxides. Carbon 116-122 delta/notch like EGF repeat containing Homo sapiens 159-162 29763293-2 2018 Herein, we fulfill significant OER improvement in both activity and stability by constructing a class of Ni(OH)2-CeO2 supported on carbon paper (Ni xCe y@CP) with an intimate hydroxide (Ni(OH)2)-oxide (CeO2) interface. Carbon 131-137 X chromosome inactivation center Homo sapiens 148-151 32997226-2 2020 A dispersion of graphene oxide-chitosan (GO-Chit) nanocomposite was used to modify the carbon working electrode, allowing for a high conjugation of anti-cystatin C antibody. Carbon 87-93 cystatin C Homo sapiens 153-163 32941515-11 2020 Stimulation of TLR3 (using poly I:C) or TLR7 (using Imiquimod) prior to ZIKV infection suppressed viral replication in a dose-dependent manner. Carbon 34-35 toll like receptor 3 Homo sapiens 15-19 29886520-0 2018 Amperometric immunoassay for the obesity biomarker amylin using a screen printed carbon electrode functionalized with an electropolymerized carboxylated polypyrrole. Carbon 81-87 islet amyloid polypeptide Homo sapiens 51-57 29886520-4 2018 It is making use of a screen printed carbon electrode (SPCE) functionalized with electropolymerized poly(pyrrole propionic acid) (pPPA) with abundant carboxyl groups that facilitate covalent binding of antibody against amylin. Carbon 37-43 islet amyloid polypeptide Homo sapiens 219-225 32873763-8 2020 Additionally, metabolism of host substrates, including mucin, was determined to support V. cholerae growth in vitro as a sole carbon source, primarily under aerobic growth conditions. Carbon 126-132 LOC100508689 Homo sapiens 55-60 29607609-4 2018 Herein, we grew vanadium-doped WS2 nanosheets on carbon cloth (V-WS2 /CC) as an electrocatalyst for HER under acidic and alkaline conditions. Carbon 49-55 grainyhead like transcription factor 3 Homo sapiens 63-68 32756632-1 2020 Correction for "Controlled functionalization of carbon nanodots for targeted intracellular production of reactive oxygen species" by Ding-Kun Ji et al., Nanoscale Horiz., 2020, 5, 1240-1249, DOI: 10.1039/D0NH00300J. Carbon 48-54 ring finger protein 2 Homo sapiens 133-137 29624891-5 2018 For OERs, the overpotential of Co@N-Carbon at 10 mA cm-2 was 400 mV (vs. reversible hydrogen electrode, RHE). Carbon 36-42 factor interacting with PAPOLA and CPSF1 Homo sapiens 104-107 29624891-7 2018 The Tafel slope of Co@N-Carbon was 61 mV dec-1 , which is comparable to that of commercial RuO2 (58 mV dec-1 ). Carbon 24-30 deleted in esophageal cancer 1 Homo sapiens 41-46 29911072-6 2018 The carbon-13 MRS results indicated that the conversion of pyruvate into lactate in GLDC-shAON-treated tumor tissues was significantly reduced, when compared with the control groups. Carbon 4-10 glycine decarboxylase Homo sapiens 84-88 29649683-11 2018 CONCLUSIONS: The results demonstrated that UGT activity modulation should be expected in the case of antitumor therapy with C-1305 or/and C-1311. Carbon 0-1 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 43-46 29649683-11 2018 CONCLUSIONS: The results demonstrated that UGT activity modulation should be expected in the case of antitumor therapy with C-1305 or/and C-1311. Carbon 3-4 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 43-46 29750440-2 2018 In this study, the facile synthesis of a 3D flower-like Cox P/carbon architecture is proposed composed of an assembly of nanosheets interconnected by silk fibroin that acts as 3D scaffolds and a carbon source. Carbon 62-68 cytochrome c oxidase subunit 8A Homo sapiens 56-59 29750440-2 2018 In this study, the facile synthesis of a 3D flower-like Cox P/carbon architecture is proposed composed of an assembly of nanosheets interconnected by silk fibroin that acts as 3D scaffolds and a carbon source. Carbon 195-201 cytochrome c oxidase subunit 8A Homo sapiens 56-59 29750440-4 2018 The flower-like Cox P/carbon can facilitate a lower overpotential, Tafel slope, charge transfer resistance, and a higher electrochemically active surface than carbon-free and silk-free Cox P. The nanostructured architecture exhibits excellent catalytic performance with low overpotentials of 109 and 121 mV at 10 mA cm-2 and Tafel slopes of 55 and 62 mV dec-1 in acidic and alkaline media, respectively. Carbon 22-28 cytochrome c oxidase subunit 8A Homo sapiens 16-19 29750440-4 2018 The flower-like Cox P/carbon can facilitate a lower overpotential, Tafel slope, charge transfer resistance, and a higher electrochemically active surface than carbon-free and silk-free Cox P. The nanostructured architecture exhibits excellent catalytic performance with low overpotentials of 109 and 121 mV at 10 mA cm-2 and Tafel slopes of 55 and 62 mV dec-1 in acidic and alkaline media, respectively. Carbon 22-28 cytochrome c oxidase subunit 8A Homo sapiens 185-188 29750440-4 2018 The flower-like Cox P/carbon can facilitate a lower overpotential, Tafel slope, charge transfer resistance, and a higher electrochemically active surface than carbon-free and silk-free Cox P. The nanostructured architecture exhibits excellent catalytic performance with low overpotentials of 109 and 121 mV at 10 mA cm-2 and Tafel slopes of 55 and 62 mV dec-1 in acidic and alkaline media, respectively. Carbon 22-28 deleted in esophageal cancer 1 Homo sapiens 354-359 29750440-4 2018 The flower-like Cox P/carbon can facilitate a lower overpotential, Tafel slope, charge transfer resistance, and a higher electrochemically active surface than carbon-free and silk-free Cox P. The nanostructured architecture exhibits excellent catalytic performance with low overpotentials of 109 and 121 mV at 10 mA cm-2 and Tafel slopes of 55 and 62 mV dec-1 in acidic and alkaline media, respectively. Carbon 159-165 cytochrome c oxidase subunit 8A Homo sapiens 16-19 29750440-5 2018 Furthermore, it minimally degrades the overpotential and current density after long-term stability tests 10 000 cyclic voltammetry cycles and a chronoamperometric test over 40 h, respectively, in acidic media, which confirms the high durability and stability of the flower-like Cox P/carbon. Carbon 284-290 cytochrome c oxidase subunit 8A Homo sapiens 278-281 29951243-3 2018 This five-coordinate iridium(I) complex cation adopts a trigonal-bipyramidal geometry with the CDP carbon and one cod double bond in axial sites. Carbon 99-105 cut like homeobox 1 Homo sapiens 95-98 29846664-3 2018 The a-CNx film with lager x, which has a larger macroscopic electric resistivity, shows a larger content of the carbon sp3: C-C bonding signal. Carbon 124-125 calnexin Homo sapiens 6-9 29573580-0 2018 Boosting ORR Catalytic Activity by Integrating Pyridine-N Dopants, a High Degree of Graphitization, and Hierarchical Pores into a MOF-Derived N-Doped Carbon in a Tandem Synthesis. Carbon 150-156 lysine acetyltransferase 8 Homo sapiens 130-133 29694013-4 2018 During carbonization, ZIF-8 polyhedrons on mesoporous CGBs are converted into N-doped carbon polyhedrons showing abundant micropores, forming a high-surface-area, high-pore-volume hierarchically porous NPC/CGB composite whose small unique pores effectively confine Se during melt diffusion, thereby providing conductive electron pathways. Carbon 7-13 chorionic gonadotropin subunit beta 5 Homo sapiens 54-57 29910939-5 2018 We discover that the DNP SENS efficiency is correlated with the hydrophilicity of the SOMF/support, which depends on the carbon and SOMF concentration. Carbon 121-127 potassium channel tetramerization domain containing 1 Homo sapiens 25-29 29695793-4 2018 Combining experimental and theoretical approaches, we demonstrate that the global carbon storage regulator CsrA controls the duration of the delay between toxin production and release and emphasize the importance of CsrA sequestering elements for the timing of ColicinE2 release. Carbon 82-88 colicin-E2 Escherichia coli 261-270 29644361-1 2018 We herein report the preparation of unique heteroatom-doped and carbon-based AuAg alloy nanoparticles (NPs) via the pyrolysis of a structurally defined octanuclear heterometallic Au(i)-Ag(i) cluster [Au4Ag4(Dppy)4(Tab)4(MeCN)4](PF6)8 (2, Dppy = diphenylphosphine-2-pyridine and Tab = 4-(trimethylammonio)benzenethiolate). Carbon 64-70 sperm associated antigen 17 Homo sapiens 228-233 29560486-4 2018 On further annealing SnO2@HCNBs in Ar, SnO2 is partially reduced to SnOx by consuming a part of carbon of HCNBs as the reducing agent, and thus SnOx@HCNBs are obtained (note that SnOx represents a composite consisting of SnO2, SnO and Sn phases). Carbon 96-102 strawberry notch homolog 1 Homo sapiens 21-24 29265577-0 2018 MOF-Derived Cobalt Phosphide/Carbon Nanocubes for Selective Hydrogenation of Nitroarenes to Anilines. Carbon 29-35 lysine acetyltransferase 8 Homo sapiens 0-3 29493235-2 2018 This study quantified carbon (C) isotope fractionation of EDB associated with anaerobic and aerobic biodegradation, abiotic degradation by iron sulfides, and abiotic hydrolysis. Carbon 22-32 vesicle associated membrane protein 8 Homo sapiens 58-61 29275249-0 2018 SnS2/SnO2 heterostructured nanosheet arrays grown on carbon cloth for efficient photocatalytic reduction of Cr(VI). Carbon 53-59 sodium voltage-gated channel alpha subunit 11 Homo sapiens 0-4 29275249-3 2018 Hence, we report an efficient preparation method for SnS2/SnO2 composites on carbon cloth (CC), for efficient photocatalytic reduction of aqueous Cr(VI). Carbon 77-83 sodium voltage-gated channel alpha subunit 11 Homo sapiens 53-57 29275249-5 2018 It was found that carbon cloth (CC) could be effectively used as a catalyst support in the obtained SnS2/SnO2 composites. Carbon 18-24 sodium voltage-gated channel alpha subunit 11 Homo sapiens 100-104 29437373-1 2018 Heat-treated polyacrylonitrile (HT-PAN), also referred to as black orlon (BO), is a promising carbon-based material used for applications in tissue engineering and regenerative medicine. Carbon 94-100 adenosine deaminase 2 Homo sapiens 35-38 29227953-5 2018 Pyrolysis conditions to prepare activated carbons from the sludge and coal mixture were examined, and the synthesized material was found to achieve the highest BET surface area of 1094 m2/g under 500 C and 30 min. Carbon 42-49 delta/notch like EGF repeat containing Homo sapiens 160-163 29299865-2 2018 With only 3 min of activation time, the BET surface area of activated carbons reached 1537.5 m2/g for impregnation mass ratio of H3PO4 to sawdust at 1:1 and activation temperature of 500 C (IR1-500), whereas it was 1750.7 m2/g for the impregnation ratio at 4:1 and activation temperature of 800 C (IR4-800). Carbon 70-77 delta/notch like EGF repeat containing Homo sapiens 40-43 29156237-4 2018 The electrochemical properties of the RCP fiber-shaped electrodes are optimized by adjusting the feeding ratio of carbon nanotubes. Carbon 114-120 CGRP receptor component Homo sapiens 38-41 29964848-1 2018 MgO/granular activated carbon (MgO/GAC-1) was prepared via an impregnation method, and its activity in ozonation of diuron and acetic acid was investigated. Carbon 23-29 ankyrin repeat domain 12 Homo sapiens 35-40 29358391-1 2018 Carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) is a five-subunit enzyme complex responsible for the carbonyl branch of the Wood-Ljungdahl (WL) pathway, considered one of the most ancient metabolisms for anaerobic carbon fixation, but its origin and evolutionary history have been unclear. Carbon 114-120 acyl-CoA synthetase short chain family member 2 Homo sapiens 51-59 29358391-6 2018 Rare intradomain and interdomain transfer events might tie into important functional transitions, including the acquisition of CODH/ACS in some archaeal methanogens not known to fix carbon, the tinkering of the complex in a clade of model bacterial acetogens, or emergence of archaeal-bacterial hybrid complexes. Carbon 182-188 acyl-CoA synthetase short chain family member 2 Homo sapiens 132-135 29028884-10 2018 Contact: alessandra.carbone@lip6.fr. Carbon 20-27 DnaJ heat shock protein family (Hsp40) member C14 Homo sapiens 28-32 29207132-0 2018 IRF3 signaling pathway serves an important role in poly(I:C)-induced procollagen reduction in human skin fibroblasts. Carbon 58-60 interferon regulatory factor 3 Homo sapiens 0-4 29380571-6 2018 Further deletion of MIG1 gene in the SNF1 deletion strain resulted in the de-repression of more genes under nitrogen catabolite repression and up-regulation of genes involved in carbon central metabolism. Carbon 178-184 transcription factor MIG1 Saccharomyces cerevisiae S288C 20-24 29299581-4 2018 The negative charge of {SnIVCl2(Pc 3-)} - is delocalized over the Pc macrocycle providing the alternation of the C-N(imine) bonds, the appearance of new bands in the NIR range and a strong blue shift of both the Soret and Q-bands in the spectrum of 1. Carbon 28-29 keratin 6A Homo sapiens 32-36 29330430-0 2018 Carbon-doped SnS2 nanostructure as a high-efficiency solar fuel catalyst under visible light. Carbon 0-6 sodium voltage-gated channel alpha subunit 11 Homo sapiens 13-17 29330430-2 2018 Using an L-cysteine-based hydrothermal process, here we synthesize a carbon-doped SnS2 (SnS2-C) metal dichalcogenide nanostructure, which exhibits a highly active and selective photocatalytic conversion of CO2 to hydrocarbons under visible-light. Carbon 69-75 sodium voltage-gated channel alpha subunit 11 Homo sapiens 82-86 29330430-2 2018 Using an L-cysteine-based hydrothermal process, here we synthesize a carbon-doped SnS2 (SnS2-C) metal dichalcogenide nanostructure, which exhibits a highly active and selective photocatalytic conversion of CO2 to hydrocarbons under visible-light. Carbon 69-75 sodium voltage-gated channel alpha subunit 11 Homo sapiens 88-94 29330430-3 2018 The interstitial carbon doping induced microstrain in the SnS2 lattice, resulting in different photophysical properties as compared with undoped SnS2. Carbon 17-23 sodium voltage-gated channel alpha subunit 11 Homo sapiens 58-62 29330430-3 2018 The interstitial carbon doping induced microstrain in the SnS2 lattice, resulting in different photophysical properties as compared with undoped SnS2. Carbon 17-23 sodium voltage-gated channel alpha subunit 11 Homo sapiens 145-149 29330430-5 2018 The SnS2-C photocatalyst represents an important contribution towards high quantum efficiency artificial photosynthesis based on gas phase photocatalytic CO2 reduction under visible light, where the in situ carbon-doped SnS2 nanostructure improves the stability and the light harvesting and charge separation efficiency, and significantly enhances the photocatalytic activity. Carbon 207-213 sodium voltage-gated channel alpha subunit 11 Homo sapiens 4-10 29330430-5 2018 The SnS2-C photocatalyst represents an important contribution towards high quantum efficiency artificial photosynthesis based on gas phase photocatalytic CO2 reduction under visible light, where the in situ carbon-doped SnS2 nanostructure improves the stability and the light harvesting and charge separation efficiency, and significantly enhances the photocatalytic activity. Carbon 207-213 sodium voltage-gated channel alpha subunit 11 Homo sapiens 4-8 29329206-1 2018 Cu2O-reduced graphene oxide nanocomposite (Cu2O-RGO) was used to modify glassy carbon electrodes (GCE), and applied for the determination of dopamine (DA). Carbon 79-85 glycine decarboxylase Homo sapiens 98-101 28946452-2 2018 Sono precipitated Ag2CrO4-C composite based photocatalysts were characterized by XRD, BET, FESEM, FTIR and UV-vis DRS and the photocatalytic activity of theses samples was evaluated in terms of degradation amount of acid orange 7 under visible light irradiations. Carbon 21-22 delta/notch like EGF repeat containing Homo sapiens 86-89 28946452-3 2018 BET analysis showed that with addition of carbon based materials, the specific surface area of the Ag2CrO4-C composite increased. Carbon 42-48 delta/notch like EGF repeat containing Homo sapiens 0-3 29599911-5 2018 Quantitative real time PCR analysis showed that expression of apoptosis-related BAX and autophagy-related Beclin1 and ATG7 was significantly enhanced by carbon ion beam alone or in combination with CDDP. Carbon 153-159 autophagy related 7 Homo sapiens 118-122 29273723-3 2017 On the basis of mechanistic studies, the copper-catalyzed successive dehydrogenation process proceeds via the initial alpha,beta-desaturation followed by further dehydrogenative desaturation of the resultant enone intermediate, demonstrating that the reactivity at alpha-carbon is transferred through carbon-carbon double bond or longer pi-system to the carbon atoms at the positions gamma, epsilon, and eta to carbonyl groups. Carbon 271-277 endothelin receptor type A Homo sapiens 125-128 29273723-3 2017 On the basis of mechanistic studies, the copper-catalyzed successive dehydrogenation process proceeds via the initial alpha,beta-desaturation followed by further dehydrogenative desaturation of the resultant enone intermediate, demonstrating that the reactivity at alpha-carbon is transferred through carbon-carbon double bond or longer pi-system to the carbon atoms at the positions gamma, epsilon, and eta to carbonyl groups. Carbon 301-307 endothelin receptor type A Homo sapiens 125-128 29273723-3 2017 On the basis of mechanistic studies, the copper-catalyzed successive dehydrogenation process proceeds via the initial alpha,beta-desaturation followed by further dehydrogenative desaturation of the resultant enone intermediate, demonstrating that the reactivity at alpha-carbon is transferred through carbon-carbon double bond or longer pi-system to the carbon atoms at the positions gamma, epsilon, and eta to carbonyl groups. Carbon 301-307 endothelin receptor type A Homo sapiens 125-128 29273723-3 2017 On the basis of mechanistic studies, the copper-catalyzed successive dehydrogenation process proceeds via the initial alpha,beta-desaturation followed by further dehydrogenative desaturation of the resultant enone intermediate, demonstrating that the reactivity at alpha-carbon is transferred through carbon-carbon double bond or longer pi-system to the carbon atoms at the positions gamma, epsilon, and eta to carbonyl groups. Carbon 301-307 endothelin receptor type A Homo sapiens 125-128 29185721-8 2017 Furthermore, the six lowest energy 12-vertex C3B8H11Re(CO)3 structures are all based on the regular icosahedron generally favored in polyhedral borane chemistry despite its complete lack of degree 4 vertices for the carbon atoms. Carbon 216-222 endogenous retrovirus group K member 3 Homo sapiens 45-48 29184928-0 2017 C-S bond induced ultrafine SnS2 dot/porous g-C3N4 sheet 0D/2D heterojunction: synthesis and photocatalytic mechanism investigation. Carbon 0-1 sodium voltage-gated channel alpha subunit 11 Homo sapiens 27-31 29184928-3 2017 Combined with various characterization techniques, it is revealed that SnS2 dots with a diameter of 3 nm distribute evenly on the surface of the g-C3N4 substrate with strong C-S bonds. Carbon 0-1 sodium voltage-gated channel alpha subunit 11 Homo sapiens 71-75 29184928-5 2017 The improved photocatalytic activities could be ascribed to the efficient electron-hole separation of porous g-C3N4, which is caused by the ultrafine SnS2 dots linked with the g-C3N4 substrate through C-S bonds. Carbon 111-112 sodium voltage-gated channel alpha subunit 11 Homo sapiens 150-154 29908181-0 2018 PPAR-gamma pathways attenuate pulmonary granuloma formation in a carbon nanotube induced murine model of sarcoidosis. Carbon 65-71 peroxisome proliferator activated receptor gamma Mus musculus 0-10 29908181-3 2018 We have previously described a murine model of multiwall carbon nanotubes (MWCNT) induced pulmonary granulomatous inflammation which bears striking similarities to pulmonary sarcoidosis, including the deficiency of alveolar macrophage PPARgamma. Carbon 57-63 peroxisome proliferator activated receptor gamma Mus musculus 235-244 30131868-12 2018 These findings provide compelling evidence that RPS3A was a key factor for modulating the brown fat-specific gene UCP-1 and carbon metabolic enzymes in EAT for preventing CAD. Carbon 124-130 ribosomal protein S3A Homo sapiens 48-53 30225018-4 2018 A satisfactory performance of the Si@N, O-doped carbon (Si@CNO) anode is gained at 25 and 55 C. The Si@CNO anode shows stable cycling performance (capacity retention of 70.0% over 100 cycles at 25 C and 60.3% over 90 cycles at 55 C with a current density of 500 mA g-1) and a superior rate capacity of 864.1 mA h g-1 at 1000 mA g-1 (25 C). Carbon 48-54 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 59-62 30225018-4 2018 A satisfactory performance of the Si@N, O-doped carbon (Si@CNO) anode is gained at 25 and 55 C. The Si@CNO anode shows stable cycling performance (capacity retention of 70.0% over 100 cycles at 25 C and 60.3% over 90 cycles at 55 C with a current density of 500 mA g-1) and a superior rate capacity of 864.1 mA h g-1 at 1000 mA g-1 (25 C). Carbon 48-54 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 103-106 30120246-7 2018 We also found that alpha-KG activates mTORC1-dependent central carbon metabolism. Carbon 63-69 CREB regulated transcription coactivator 1 Mus musculus 38-44 29664234-1 2018 In C4 photosynthesis, pyruvate orthophosphate dikinase (PPDK) catalyzes the regeneration of phosphoenolpyruvate in the carbon shuttle pathway. Carbon 119-125 pyruvate, phosphate dikinase 1, chloroplastic Zea mays 56-60 29759176-1 2018 In this work, carbon nanosphere (CNS)-based fluorescence "turn off/on" aptasensor was developed for targeted detection of breast cancer cell MCF-7 by conjugation with FAM (a dye)-labeled mucin1 (MUC1) aptamer P0 (P0-FAM), which can recognize MUC1 protein overexpressed on the surface of MCF-7. Carbon 14-20 mucin 1, cell surface associated Homo sapiens 187-193 29759176-1 2018 In this work, carbon nanosphere (CNS)-based fluorescence "turn off/on" aptasensor was developed for targeted detection of breast cancer cell MCF-7 by conjugation with FAM (a dye)-labeled mucin1 (MUC1) aptamer P0 (P0-FAM), which can recognize MUC1 protein overexpressed on the surface of MCF-7. Carbon 14-20 mucin 1, cell surface associated Homo sapiens 195-199 29759176-1 2018 In this work, carbon nanosphere (CNS)-based fluorescence "turn off/on" aptasensor was developed for targeted detection of breast cancer cell MCF-7 by conjugation with FAM (a dye)-labeled mucin1 (MUC1) aptamer P0 (P0-FAM), which can recognize MUC1 protein overexpressed on the surface of MCF-7. Carbon 14-20 mucin 1, cell surface associated Homo sapiens 242-246 30068164-7 2018 Almost 83% of atomic hydrogen elimination occurs through the asynchronous concerted mechanism from the terminal carbon atom via triple dissociation leading to CH3 + C2H4 + H products. Carbon 112-118 COP9 signalosome subunit 3 Drosophila melanogaster 159-162 29611887-2 2018 Herein, we synthesize a fluorine-doped carbon (FC) catalyst by pyrolyzing commercial BP 2000 with a fluorine source, enabling a highly selective CO2 -to-CO conversion with a maximum Faradaic efficiency of 90 % at a low overpotential of 510 mV and a small Tafel slope of 81 mV dec-1 , outcompeting current metal-free catalysts. Carbon 39-45 deleted in esophageal cancer 1 Homo sapiens 276-281 29870126-0 2018 Gold-Catalyzed C-S Aryl-Group Transfer in Zinc Finger Proteins. Carbon 5-6 zinc finger protein 763 Homo sapiens 42-53 31458926-3 2018 A Co0.20Fe0.80OOH-coated glassy carbon electrode generated a current density (j) of 10 mA cm-2 at an overpotential (eta) as small as 383 mV (1.61 V vs the reversible hydrogen electrode) in an alkaline electrolyte, with a small Tafel slope of 40 mV dec-1 and excellent durability, whereas pure alpha-FeOOH required eta = 580 mV to reach the same current density. Carbon 32-38 endothelin receptor type A Homo sapiens 314-317 29889506-1 2018 We examine the DNA polymerase beta (pol beta) transition state (TS) from a leaving group pre-steady-state kinetics perspective by measuring the rate of incorporation of dNTPs and corresponding novel beta,gamma-CXY-dNTP analogues, including individual beta,gamma-CHF and -CHCl diastereomers with defined stereochemistry at the bridging carbon, during the formation of right (R) and wrong (W) base pairs. Carbon 335-341 DNA polymerase beta Homo sapiens 15-34 29889506-1 2018 We examine the DNA polymerase beta (pol beta) transition state (TS) from a leaving group pre-steady-state kinetics perspective by measuring the rate of incorporation of dNTPs and corresponding novel beta,gamma-CXY-dNTP analogues, including individual beta,gamma-CHF and -CHCl diastereomers with defined stereochemistry at the bridging carbon, during the formation of right (R) and wrong (W) base pairs. Carbon 335-341 DNA polymerase beta Homo sapiens 36-44 28699008-1 2018 Magnetite (Fe3O4) nanoparticle-encapsulated mesoporous carbon nanocomposite was fabricated from Fe-based metal-organic framework (MOF) (MIL-102) through carbonization. Carbon 55-61 lysine acetyltransferase 8 Homo sapiens 105-134 28699008-2 2018 It was found that Fe-based MOF (MIL-102) is a potential precursor for the fabrication of hexagonal mesoporous carbon nanodisk functionalized with Fe3O4 nanoparticles. Carbon 110-116 lysine acetyltransferase 8 Homo sapiens 27-30 29748796-1 2018 In order to degrade the macromolecular pollutant of humic acid, the powder ordered mesoporous carbon (POMC, average pore diameter 4.29 nm) was first applied for preparing the granular OMC (GOMC, Phi x H = 4 x 3-6 mm) as electrodes in a continuous three-dimensional (3D) electrochemical system. Carbon 94-100 glucose-6-phosphate isomerase Homo sapiens 195-198 29888793-1 2018 Cytochrome P450 17A1 (CYP17A1) catalyzes the synthesis of androgens from the steroid precursors pregnenolone and progesterone in a two-step reaction process: allylic hydroxylation and carbo-carbon bond scission. Carbon 190-196 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 0-20 29888793-1 2018 Cytochrome P450 17A1 (CYP17A1) catalyzes the synthesis of androgens from the steroid precursors pregnenolone and progesterone in a two-step reaction process: allylic hydroxylation and carbo-carbon bond scission. Carbon 190-196 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 22-29 29742810-7 2018 When at4g16800 knockout plants were subjected to dark-induced carbon starvation, their rosette leaves displayed accelerated senescence as compared with control plants, and this phenotype was paralleled by a marked increase in the accumulation of free and total leucine, isoleucine and valine. Carbon 62-68 ATP-dependent caseinolytic (Clp) protease/crotonase family protein Arabidopsis thaliana 5-14 29683211-2 2018 Here, we report the discovery of a general procedure for an SN 2 reaction catalyzed by Pd/Ding-SKP-type ligands, and that occurs between Colby pro-enolates with MBH carbonates to afford the corresponding products featuring two consecutive stereogenic carbons, including a C-F quaternary stereogenic center. Carbon 251-258 ring finger protein 2 Homo sapiens 90-94 29683211-2 2018 Here, we report the discovery of a general procedure for an SN 2 reaction catalyzed by Pd/Ding-SKP-type ligands, and that occurs between Colby pro-enolates with MBH carbonates to afford the corresponding products featuring two consecutive stereogenic carbons, including a C-F quaternary stereogenic center. Carbon 137-138 ring finger protein 2 Homo sapiens 90-94 29447669-3 2018 For this purpose, addressed herein, as a novel glucose sensor, highly sensitive activated carbon (AC) decorated monodisperse nickel and palladium alloy nanocomposites modified glassy carbon electrode (Ni-Pd@AC/GCE NCs) have been synthesized by in-situ reduction technique. Carbon 90-96 glycine decarboxylase Homo sapiens 204-213 29447669-3 2018 For this purpose, addressed herein, as a novel glucose sensor, highly sensitive activated carbon (AC) decorated monodisperse nickel and palladium alloy nanocomposites modified glassy carbon electrode (Ni-Pd@AC/GCE NCs) have been synthesized by in-situ reduction technique. Carbon 183-189 glycine decarboxylase Homo sapiens 204-213 29447669-6 2018 In addition, the Ni-Pd@AC/GCE nanocomposites showed a very low detection limit of 0.014 muM, a wide linear range of 0.01 mM-1 mM and a very high sensitivity of 90 mA mM-1 cm-2. Carbon 23-25 glycine decarboxylase Homo sapiens 26-29 29426214-6 2018 Further study showed that CO2 inhibited carbon source utilization because of multiple negative influences: (1) suppressing the growth and viability of denitrifier cells, (2) weakening the driving force for carbon source transport by decreasing bacterial membrane potential, and (3) downregulating the expression of genes encoding key enzymes involved in intracellular carbon metabolism, such as citrate synthase, aconitate hydratase, isocitrate dehydrogenase, succinate dehydrogenase, and fumarate reductase. Carbon 40-46 citrate synthase Homo sapiens 395-411 29904112-2 2018 It is established that the ordering of substitutional impurity atoms on nodes of the crystal lattice causes the appearance of a gap in the energy spectrum of graphene with width eta delta centered at the point ydelta, where eta is the parameter of ordering, delta is the difference of the scattering potentials of impurity atoms and carbon atoms, and y is the impurity concentration. Carbon 334-340 endothelin receptor type A Homo sapiens 178-181 29904112-2 2018 It is established that the ordering of substitutional impurity atoms on nodes of the crystal lattice causes the appearance of a gap in the energy spectrum of graphene with width eta delta centered at the point ydelta, where eta is the parameter of ordering, delta is the difference of the scattering potentials of impurity atoms and carbon atoms, and y is the impurity concentration. Carbon 334-340 endothelin receptor type A Homo sapiens 225-228 29708761-2 2018 Such a strategy is achieved by the in situ and high-level doping of nitrogen atoms into carbon nanospheres (ANCS), which increases the carbon defects and active sites, inducing more rapidly capacitive charge-storage contributions for both Li+ storage anodes and PF6- storage cathodes. Carbon 88-94 sperm associated antigen 17 Homo sapiens 262-265 29808214-1 2018 Zhang and co-workers have recently advanced the carbon [5 + 2] cycloaddition of vinylcyclopropane and alkyne (VCP-alkyne) to the hetero-[5 + 2] cycloaddition of vinyloxirane with alkyne (VOR-alkyne). Carbon 48-54 valosin containing protein Homo sapiens 110-113 29649474-1 2018 This work reports an amperometric enzyme-electrode prepared with glucose oxidase, which have been immobilized by a cross-linking step with glutaraldehyde in a mixture containing albumin and a novel carbon nanotubes-mucin composite (CNT-muc). Carbon 198-204 LOC100508689 Homo sapiens 215-220 29541883-1 2018 KEY MESSAGE: Inclusion of carbon nanoparticles in growth medium accelerates timing to flower by down-regulating phytochrome B in a CONSTANS-independent but photoperiod-dependent manner in Arabidopsis thaliana. Carbon 26-32 phytochrome B Arabidopsis thaliana 112-125 29898548-1 2018 The parent activated carbon (ACP) was modified with urea and thiourea to obtain N-doped activated carbon (ACN) and N, S co-doped activated carbon (ACNS), respectively. Carbon 21-27 CPAT1 Homo sapiens 29-32 29898548-1 2018 The parent activated carbon (ACP) was modified with urea and thiourea to obtain N-doped activated carbon (ACN) and N, S co-doped activated carbon (ACNS), respectively. Carbon 98-104 CPAT1 Homo sapiens 29-32 29898548-1 2018 The parent activated carbon (ACP) was modified with urea and thiourea to obtain N-doped activated carbon (ACN) and N, S co-doped activated carbon (ACNS), respectively. Carbon 106-109 CPAT1 Homo sapiens 29-32 29898548-1 2018 The parent activated carbon (ACP) was modified with urea and thiourea to obtain N-doped activated carbon (ACN) and N, S co-doped activated carbon (ACNS), respectively. Carbon 98-104 CPAT1 Homo sapiens 29-32 29962372-7 2018 HOSCN decreased polyI:C-induced apoptosis and the expression levels of IFNB1, IFNL1, IFNL2 and IFNL3 mRNAs. Carbon 3-4 interferon beta 1 Homo sapiens 71-76 29962372-7 2018 HOSCN decreased polyI:C-induced apoptosis and the expression levels of IFNB1, IFNL1, IFNL2 and IFNL3 mRNAs. Carbon 3-4 interferon lambda 1 Homo sapiens 78-83 29962372-7 2018 HOSCN decreased polyI:C-induced apoptosis and the expression levels of IFNB1, IFNL1, IFNL2 and IFNL3 mRNAs. Carbon 3-4 interferon lambda 2 Homo sapiens 85-90 29708744-4 2018 The SAR study revealed a relationship between the length of the residues at carbon C-3 of the steroid molecule and the positive modulatory effect at GluN1/GluN2B receptors for various D-ring modifications. Carbon 76-82 glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens 155-161 29717862-0 2018 MOF-Templated N-Doped Carbon-Coated CoSe2 Nanorods Supported on Porous CNT Microspheres with Excellent Sodium-Ion Storage and Electrocatalytic Properties. Carbon 22-28 lysine acetyltransferase 8 Homo sapiens 0-3 29717865-3 2018 Remarkably, due to the synergistic effects of MoP nanocrystals, P dopant, and porous carbon, the resulting MoP@PC composite exhibits superior HER catalytic activity with an onset overpotential of 97 mV, a Tafel slope of 59.3 mV dec-1, and good long-term durability, which compares to those of most reported MoP-based HER catalysts. Carbon 85-91 deleted in esophageal cancer 1 Homo sapiens 228-233 29666849-0 2018 A rational microstructure design of SnS2-carbon composites for superior sodium storage performance. Carbon 41-47 sodium voltage-gated channel alpha subunit 11 Homo sapiens 36-40 29666849-3 2018 To address these problems, herein, a rational microstructure of the SnS2-carbon composite has been designed for superior performance, which consists of MWNTs as a carbon matrix, the SnS2 nanosheet (NS) as an active material, the outer carbon coating as a protection layer, as well as the interior void space for volume accommodation. Carbon 73-79 sodium voltage-gated channel alpha subunit 11 Homo sapiens 68-72 29666849-3 2018 To address these problems, herein, a rational microstructure of the SnS2-carbon composite has been designed for superior performance, which consists of MWNTs as a carbon matrix, the SnS2 nanosheet (NS) as an active material, the outer carbon coating as a protection layer, as well as the interior void space for volume accommodation. Carbon 73-79 sodium voltage-gated channel alpha subunit 11 Homo sapiens 182-186 29666849-3 2018 To address these problems, herein, a rational microstructure of the SnS2-carbon composite has been designed for superior performance, which consists of MWNTs as a carbon matrix, the SnS2 nanosheet (NS) as an active material, the outer carbon coating as a protection layer, as well as the interior void space for volume accommodation. Carbon 163-169 sodium voltage-gated channel alpha subunit 11 Homo sapiens 68-72 29666849-3 2018 To address these problems, herein, a rational microstructure of the SnS2-carbon composite has been designed for superior performance, which consists of MWNTs as a carbon matrix, the SnS2 nanosheet (NS) as an active material, the outer carbon coating as a protection layer, as well as the interior void space for volume accommodation. Carbon 163-169 sodium voltage-gated channel alpha subunit 11 Homo sapiens 68-72 29206217-3 2017 The simultaneous thermogravimetric and mass spectrometry analyses of the EtOSZ under helium revealed cleavage of oxygen-carbon bond of the EtO group to evolve ethylene as a main gaseous species formed in-situ, which lead to the formation at 800 C of quaternary amorphous Si-C-N with an extremely low carbon content (1.1 wt %) when compared to the theoretical EtOSZ (25.1 wt %). Carbon 120-126 RUNX1 partner transcriptional co-repressor 1 Homo sapiens 73-76 29206217-3 2017 The simultaneous thermogravimetric and mass spectrometry analyses of the EtOSZ under helium revealed cleavage of oxygen-carbon bond of the EtO group to evolve ethylene as a main gaseous species formed in-situ, which lead to the formation at 800 C of quaternary amorphous Si-C-N with an extremely low carbon content (1.1 wt %) when compared to the theoretical EtOSZ (25.1 wt %). Carbon 301-307 RUNX1 partner transcriptional co-repressor 1 Homo sapiens 73-76 28868805-0 2017 Formation of Palladium eta2 -Bound Chalcogenoketones across a Pd+ -C- Bond. Carbon 35-36 DNA polymerase iota Homo sapiens 23-27 28881241-1 2017 Electrochemistry coupled with granulated activated carbon catalysis of peroxymonosulfate (electro/GAC/PMS) as a novel wastewater treatment process was performed for the degradation of Acid Orange 7 (AO7) in aqueous solution. Carbon 51-57 proline rich protein BstNI subfamily 1 Homo sapiens 102-105 32806104-1 2020 The binaphthyl stabilized palladium nanoparticles (Pd-BNP) catalyzed single-step, stereoselective domino synthesis of symmetrically and unsymmetrically all-carbon tetrasubstituted olefin containing oxindoles from readily accessible anilides has been developed. Carbon 156-162 natriuretic peptide B Homo sapiens 54-57 29278816-4 2018 Uniform colloidal 15nm graphite-like nitride doped carbon quantum dots-capped gold nanoparticle (Au@g-CNQDs) was successfully prepared, wherein the existence of numerous heptazine, carboxyl and hydroxyl groups on the nanoparticle"s surface strengthened adsorption of the Cd2+ ions on the surface of Au@g-CNQDs through the "cooperative effect". Carbon 51-57 CD2 antigen Mus musculus 271-274 28278784-1 2017 Carbon nanotube (CNT) and graphene oxide (GO) as common nanostructures were modified with silver sulfide (Ag2S) using chemical vapor deposition. Carbon 0-6 angiotensin II receptor type 1 Homo sapiens 106-110 32814778-6 2020 Rad53-Spt21 mutants display severe glucose dependence, caused by excess histones through two separable mechanisms: dampening of acetyl-coenzyme A-dependent carbon metabolism through histone hyper-acetylation, and Sirtuin-mediated silencing of starvation-induced subtelomeric domains. Carbon 156-162 checkpoint kinase 2 Homo sapiens 0-5 28497245-2 2017 Inorganic carbon takes the forms of "CO2" (dissolved CO2 and carbonic acid) and "CARB" (bicarbonate and carbonate ions), which are substitutable in their effects on algal growth. Carbon 10-16 syntaxin 8 Homo sapiens 81-85 29616556-0 2018 Triaxial Nanocables of Conducting Polypyrrole@SnS2@Carbon Nanofiber Enabling Significantly Enhanced Li-Ion Storage. Carbon 51-57 sodium voltage-gated channel alpha subunit 11 Homo sapiens 46-50 29616556-2 2018 Herein, we demonstrate unique triaxial nanocables of conducting polypyrrole@SnS2@carbon nanofiber (PPy@SnS2@CNF) prepared via a facile combination of hydrothermal method and vapor-phase polymerization. Carbon 81-87 sodium voltage-gated channel alpha subunit 11 Homo sapiens 76-80 29616556-2 2018 Herein, we demonstrate unique triaxial nanocables of conducting polypyrrole@SnS2@carbon nanofiber (PPy@SnS2@CNF) prepared via a facile combination of hydrothermal method and vapor-phase polymerization. Carbon 81-87 sodium voltage-gated channel alpha subunit 11 Homo sapiens 103-107 32825155-3 2020 Carbon fibers are recycled from waste CFRPs by an electrochemical catalytic reaction with the assistance of phosphotungstic acid (PA), which promotes the depolymerization of diglycidyl ether of bisphenol A/ethylenediamine (DGEBA/EDA) epoxy resin. Carbon 0-6 ectodysplasin A Homo sapiens 229-232 29533404-8 2018 Further above 750 K, the calculated high pressure limit rate constants indicate that the total contribution from delta carbon sites (Cdelta) is predominant for hydrogen atom abstraction by the H atom and HO2 radical. Carbon 119-125 heme oxygenase 2 Homo sapiens 204-207 29123071-7 2017 Thus, SAMTOR is a SAM sensor that links methionine and one-carbon metabolism to mTORC1 signaling. Carbon 59-65 CREB regulated transcription coactivator 1 Mus musculus 80-86 32454326-10 2020 We functionally challenged ovaries in vitro, by polyinosinic:polycytidylic acid (poly I:C) and LPS, known to activate TLR3 and TLR4, respectively, and found a tendency for increased IL-6 production, which was particular evident in the LPS-treated group. Carbon 88-89 toll like receptor 3 Homo sapiens 118-122 28811146-8 2017 At a low influent COD/NH4+-N ratio (2.7), the N2O conversion rate was greater when there were more biodegradable carbon substrates. Carbon 113-119 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 18-21 29561807-3 2018 Benefitting from its hierarchical porosity, inherited from the natural structure of corncob, high BET surface area (1471.4 m2 g-1) and excellent electrical conductivity, the novel carbon material exhibited a specific capacitance of 293 F g-1 at 1 A g-1 in 6 M KOH electrolyte and maintained at 195 F g-1 at 5 A g-1. Carbon 180-186 delta/notch like EGF repeat containing Homo sapiens 98-101 32736477-8 2020 XPS also confirmed the presence of carbon in the form of sp3(C-C), sp2(C=C), C-O, and C=O bonds in the Si-DLC coatings; it showed that postprocessing treatments significantly increased the percentage of oxygen in the Si-DLC coatings. Carbon 35-41 trans-acting transcription factor 3 Mus musculus 57-60 29509193-0 2018 Label-free fluorescence imaging of cytochrome c in living systems and anti-cancer drug screening with nitrogen doped carbon quantum dots. Carbon 117-123 cytochrome c, somatic b Danio rerio 35-47 28881163-6 2017 Experimental evidences on positive or negative regulators of TLR3-mediated apoptosis induced by poly(I:C) are reported and strategies are proposed to successfully promote this event in cancer cells. Carbon 103-104 toll like receptor 3 Homo sapiens 61-65 27569025-6 2018 Further structure/activity studies indicated 3-methyl-branched aliphatic aldehydes with a carbon chain of >=4 C atoms as best TAS2R43 antagonists. Carbon 90-96 taste 2 receptor member 43 Homo sapiens 129-136 32573248-1 2020 Mechanically interlocking redox-active anthraquinone (AQ) like a rotaxane onto single-walled carbon nanotubes (AQ-MINT) gives a new and advanced example of a non-covalent architecture for an electrochemical platform. Carbon 93-99 spen family transcriptional repressor Homo sapiens 114-118 29451291-4 2018 The CoII-MOF modified glassy carbon electrode (GCE) shows good electrocatalytic activity towards glucose oxidation. Carbon 29-35 lysine acetyltransferase 8 Homo sapiens 9-12 28814397-0 2017 Association of TCN2 rs1801198 c.776G>C polymorphism with markers of one-carbon metabolism and related diseases: a systematic review and meta-analysis of genetic association studies. Carbon 72-78 transcobalamin 2 Homo sapiens 15-19 29692129-2 2017 The results showed that the total carbon storage at tree layer in Tibet forest ecosystem was 1.067x109 t and the average carbon density was 72.49 t hm-2. Carbon 121-127 cholinergic receptor muscarinic 2 Homo sapiens 148-152 32679786-1 2020 Two activated carbons (ACs) were prepared from peat using thermochemical K2SO4 activation at 1053-1133 K for 1h, and steam activation at 1173K for 30 (AC-4) and 45 (AC-6) min. Carbon 14-21 adenylate cyclase 6 Homo sapiens 165-169 29692129-5 2017 The proportion of the first mentioned two was 88.5%, and the average carbon density of different forest types at tree layer was 88.09 t hm-2. Carbon 69-75 cholinergic receptor muscarinic 2 Homo sapiens 136-140 29522437-2 2018 The precipitation of fine WC grains and eta-phase occurs at the interface of the alloy with the low carbon content. Carbon 100-106 endothelin receptor type A Homo sapiens 40-43 32394038-1 2020 Considering the importance of hydrogen peroxide (H2O2) rapid detection, a SnS2/MWCNTs composite was prepared by loading tin disulfide (SnS2) nanoparticles on a three-dimensional conductive network composed of multi-walled carbon nanotubes (MWCNTs). Carbon 222-228 sodium voltage-gated channel alpha subunit 11 Homo sapiens 74-78 29405065-1 2018 An efficient and diastereoselective decarboxylative oxa-1,3-dipolar cycloaddition between 3-oxindoles and diverse amino acids is developed to access novel oxazolidine-dispirooxindole skeletons bearing vicinal quaternary carbon centers. Carbon 220-226 OXA1L mitochondrial inner membrane protein Homo sapiens 52-57 29310259-6 2018 In comparison with glassy carbon electrode (GCE) and nitrogen-doped carbon (NC) modified GCE, the CoxP/NC modified GCE (CoxP/NC/GCE) showed a remarkable increase in DPV current toward 4-NP. Carbon 26-32 glycine decarboxylase Homo sapiens 120-131 29310259-6 2018 In comparison with glassy carbon electrode (GCE) and nitrogen-doped carbon (NC) modified GCE, the CoxP/NC modified GCE (CoxP/NC/GCE) showed a remarkable increase in DPV current toward 4-NP. Carbon 68-74 glycine decarboxylase Homo sapiens 89-92 28801461-10 2017 Third, an Arg-Asp dipeptide immediately preceding the ZF helix, conserved in two PRDM9a fingers and three PRDM9c fingers, permits adaptability to variations from a C:G base pair (G-Arg interaction) to a G:C base pair (C-Asp interaction). Carbon 164-165 PR/SET domain 9 Homo sapiens 81-86 29018344-1 2017 Xanthates (alkyl or aryl derivatives of dithiocarbonic acid) have been shown to be selective mechanism-based inactivators of cytochromes P450 2B1/2B6 and 2E1 due to covalent binding of a reactive intermediate to apoprotein after double hydrogen abstraction at alpha-carbon atom, suggesting interaction of the xanthate dithiocarbonic head with the enzyme heme. Carbon 46-52 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 125-157 29310259-6 2018 In comparison with glassy carbon electrode (GCE) and nitrogen-doped carbon (NC) modified GCE, the CoxP/NC modified GCE (CoxP/NC/GCE) showed a remarkable increase in DPV current toward 4-NP. Carbon 68-74 glycine decarboxylase Homo sapiens 89-92 29310259-6 2018 In comparison with glassy carbon electrode (GCE) and nitrogen-doped carbon (NC) modified GCE, the CoxP/NC modified GCE (CoxP/NC/GCE) showed a remarkable increase in DPV current toward 4-NP. Carbon 68-74 glycine decarboxylase Homo sapiens 120-131 32490863-0 2020 Elevated amyloidoses of human IAPP and amyloid beta by lipopolysaccharide and their mitigation by carbon quantum dots. Carbon 98-104 islet amyloid polypeptide Homo sapiens 30-34 29796388-8 2018 Consistent with this conclusion, the cyc8 TPR mutations partially restored growth on alternative carbon sources and significantly extended CLS compared to the snf1 parent. Carbon 97-103 transcription regulator CYC8 Saccharomyces cerevisiae S288C 37-41 28762587-2 2017 To date the reported carbon cages of CYCFs are limited to C82 and C76 , and little is known about the chemical reactivity of CYCFs. Carbon 21-27 complement C8 beta chain Homo sapiens 58-61 32463654-3 2020 The sulfur in the raw SnS2 directly induces the sulfur-doped amorphous carbon layer onto the in situ reduced SnS nanosheet. Carbon 71-77 sodium voltage-gated channel alpha subunit 11 Homo sapiens 22-26 29266417-0 2018 MOF-Derived Bifunctional Cu3 P Nanoparticles Coated by a N,P-Codoped Carbon Shell for Hydrogen Evolution and Oxygen Reduction. Carbon 69-75 lysine acetyltransferase 8 Homo sapiens 0-3 29266417-2 2018 For the first time, a Cu-based MOF, i.e., Cu-NPMOF is used, whose linkers contain nitrogen and phosphorus heteroatoms, as a single precursor and template to prepare novel Cu3 P nanoparticles (NPs) coated by a N,P-codoped carbon shell that is extended to a hierarchical porous carbon matrix with identical uniform N and P doping (termed Cu3 P@NPPC) as an electrocatalyst. Carbon 221-227 lysine acetyltransferase 8 Homo sapiens 31-34 29266417-2 2018 For the first time, a Cu-based MOF, i.e., Cu-NPMOF is used, whose linkers contain nitrogen and phosphorus heteroatoms, as a single precursor and template to prepare novel Cu3 P nanoparticles (NPs) coated by a N,P-codoped carbon shell that is extended to a hierarchical porous carbon matrix with identical uniform N and P doping (termed Cu3 P@NPPC) as an electrocatalyst. Carbon 276-282 lysine acetyltransferase 8 Homo sapiens 31-34 28500630-5 2018 Carbon ion IR could induce up-regulation of E2F1 expression in cancer cells. Carbon 0-6 E2F transcription factor 1 L homeolog Xenopus laevis 44-48 28912540-0 2017 SOX9 Regulates Cancer Stem-Like Properties and Metastatic Potential of Single-Walled Carbon Nanotube-Exposed Cells. Carbon 85-91 SRY-box transcription factor 9 Homo sapiens 0-4 32045805-5 2020 Benefiting from the excellent electrical conductivity and high specific surface area of the NHC which is superior to other carbon material and the favorable band gap of ZnIn2S4 makes ZIS-NHC has superior light-driven photocatalytic efficiency. Carbon 123-129 zinc finger RANBP2-type containing 2 Homo sapiens 183-186 28912540-4 2017 In this study, we linked SOX9, a stem cell associated transcription factor, to the neoplastic-like properties of human lung epithelial cells chronically exposed to a low-dose of single-walled carbon nanotubes (SWCNTs). Carbon 192-198 SRY-box transcription factor 9 Homo sapiens 25-29 32420915-1 2020 Phosphoglycerate dehydrogenase (PHGDH) catalyzes the first step in the synthesis of the amino acid serine, important for protein synthesis, one-carbon metabolism, lipid production, redox homeostasis, and other key processes of normal and cancer metabolism. Carbon 144-150 phosphoglycerate dehydrogenase Homo sapiens 0-30 28903780-0 2017 Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework. Carbon 69-75 signal transducer and activator of transcription 6 Mus musculus 0-6 28763763-2 2018 Moderately fluorescing carbon dots (lambdaex=360nm and lambdaem=440nm) of 6-8nm diameters (CDA) have been synthesized from freshly prepared aqueous ascorbic acid solution under modified hydrothermal treatment. Carbon 23-29 cytidine deaminase Homo sapiens 91-94 32420915-1 2020 Phosphoglycerate dehydrogenase (PHGDH) catalyzes the first step in the synthesis of the amino acid serine, important for protein synthesis, one-carbon metabolism, lipid production, redox homeostasis, and other key processes of normal and cancer metabolism. Carbon 144-150 phosphoglycerate dehydrogenase Homo sapiens 32-37 31928284-0 2020 Fate of GdF3 nanoparticles-loaded PEGylated carbon capsules inside mice model: a step toward clinical application. Carbon 44-50 growth differentiation factor 3 Mus musculus 8-12 29372902-3 2018 The cytoplasmic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae, ERG10, catalyses carbon-carbon bond formation in the mevalonate pathway. Carbon 89-95 acetyl-CoA C-acetyltransferase Saccharomyces cerevisiae S288C 72-77 29372902-3 2018 The cytoplasmic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae, ERG10, catalyses carbon-carbon bond formation in the mevalonate pathway. Carbon 96-102 acetyl-CoA C-acetyltransferase Saccharomyces cerevisiae S288C 72-77 28883659-6 2017 The optimal carbon electrode obtained particularly at 900 C (URC-900) possesses high BET surface area (1040.5 m2g-1), good conductivity, and efficient heteroatom doping of N, S, and P, illustrating high specific capacitance of 166 Fg-1 at 0.5 Ag-1 for three-electrode system in inorganic electrolyte. Carbon 12-18 delta/notch like EGF repeat containing Homo sapiens 86-89 31928284-2 2020 Herein, we have investigated the in vitro cyto-hemocompatibility, in vivo biodistribution, clearance, and toxicity in mice after systemic administration of GdF3 nanoparticles loaded PEGylated mesoporous carbon capsule (GdF3-PMCC)-based theranostic system. Carbon 203-209 growth differentiation factor 3 Mus musculus 156-160 31558185-4 2020 PRKAA1 downregulation by shRNA or treatment of AMPK inhibitor compound C significantly inhibited proliferation as well as promoted cell cycle arrest and apoptosis of BGC-823 and MKN45 cells. Carbon 71-72 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 0-6 28872593-5 2017 The Ag-N-ZnO/coconut husk activated carbon (Ag-N-ZnO/CHAC) exhibited the highest degradation efficiency of 98.82% for MO under visible light irradiation. Carbon 36-42 vacuolar protein sorting 13 homolog A Homo sapiens 53-57 29998959-2 2018 DET is achieved by placing a single-walled carbon nanotube (CNT) between GDH and a flat gold electrode where the CNT is close to FAD within the distance for DET. Carbon 43-49 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 73-76 29343628-9 2018 Recently, it has been shown that AMPK can also sense the availability of glucose, the primary carbon source for most eukaryotic cells, via a mechanism independent of changes in AMP or ADP. Carbon 94-100 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 33-37 31558185-4 2020 PRKAA1 downregulation by shRNA or treatment of AMPK inhibitor compound C significantly inhibited proliferation as well as promoted cell cycle arrest and apoptosis of BGC-823 and MKN45 cells. Carbon 71-72 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 47-51 32444944-5 2020 The Ta-C/f-MWCNT-modified glassy carbon electrode (Ta-C/f-MWCNT/GCE) was successfully utilized as an active electrocatalyst for the detection of NFT in the presence of 0.384 mM NFT containing 0.05 M phosphate buffer (pH 7) at a scan rate of 50 mV/s. Carbon 33-39 TATA-box binding protein associated factor 8 Homo sapiens 4-10 28802176-6 2017 Electrochemical characterization demonstrated the role of cytochrome c on electron transfer reactions, leading to a current density of up to 300muAcm-2 in the presence of 50mM formate when a porous carbon felt electrode is used as support for the biocomposite. Carbon 198-204 LOC104968582 Bos taurus 58-70 32444944-5 2020 The Ta-C/f-MWCNT-modified glassy carbon electrode (Ta-C/f-MWCNT/GCE) was successfully utilized as an active electrocatalyst for the detection of NFT in the presence of 0.384 mM NFT containing 0.05 M phosphate buffer (pH 7) at a scan rate of 50 mV/s. Carbon 33-39 TATA-box binding protein associated factor 8 Homo sapiens 51-57 32398698-5 2020 Methotrexate-induced AMPK activation leads to decreased one-carbon metabolism gene expression and cellular proliferation as well as increased global bioenergetic capacity. Carbon 60-66 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 21-25 32030866-2 2020 Here, we design a three-in-one surface treatment via the pyrolysis of urea to improve the voltage and capacity stability of Li1.2Mn0.6Ni0.2O2 (LMNO), by which oxygen vacancy, spinel phase integration and N-doped carbon nanolayer are synchronously built on the surface of LMNO microspheres. Carbon 212-218 transglutaminase 1 Homo sapiens 124-127 32321826-4 2020 Methyl vinyl ketone oxide (MVK-oxide) is a four-carbon, asymmetric, resonance-stabilized CI, produced with 21 to 23% yield from isoprene ozonolysis, yet its reactivity has not been directly studied. Carbon 48-54 mevalonate kinase Homo sapiens 27-30 32314921-4 2020 On the basis of three advantages, as the enhancement of the intrinsic activity using the ternary sulfoselenide, increased number of exposed active sites due to the 3D hollow substrate, and increased conductivity caused by porous-carbon skeletons, the resulting porous-C/Ni2SeS requires an overpotential of only 121 mV at a current density of 10 mA cm-2 with a Tafel slope of 78 mV dec-1 for hydrogen evolution in acidic media and a good long-term stability. Carbon 229-235 deleted in esophageal cancer 1 Homo sapiens 381-386 31958511-6 2020 Further study showed that TRIM7 interacted with p65 via its C-terminal which is different from GNIP1. Carbon 60-61 RELA proto-oncogene, NF-kB subunit Homo sapiens 48-51 32061643-7 2020 OPN mRNA resulted lower in C with respect to A and B while miRNA-181a expression was significantly increased as a function of age. Carbon 27-28 secreted phosphoprotein 1 Rattus norvegicus 0-3 32016283-2 2020 Platelet SFKs are inhibited by C-terminal Src kinase (Csk), which phosphorylates a conserved tyrosine in their C-terminal tail, and are activated by the receptor-type tyrosine phosphatase PTPRJ (CD148, DEP-1), which dephosphorylates the same residue. Carbon 31-32 diabetic embryopathy 1 Mus musculus 202-207 32270832-1 2020 The steady state fluorescence anisotropy of carbon dot solutions of different viscosities eta and its variation with temperature T has been investigated. Carbon 44-50 endothelin receptor type A Homo sapiens 90-93 31860881-0 2020 Al-based MOF derived self-assembled carbon nanosheets as innovative anodes for Li- and Na-ion batteries. Carbon 36-42 lysine acetyltransferase 8 Homo sapiens 9-12 31697442-5 2020 Next-generation RNA sequencing identified a novel fusion transcript, in which the in-frame junctional reads contained exon 9 of EWSR1 and exon 2 of VGLL1, resulting in the formation of a putative chimeric protein with the N-terminal transcriptional activation domain (TAD) of EWSR1 and C-terminal full length of the VGLL1 protein. Carbon 286-287 EWS RNA binding protein 1 Homo sapiens 128-133 31697442-5 2020 Next-generation RNA sequencing identified a novel fusion transcript, in which the in-frame junctional reads contained exon 9 of EWSR1 and exon 2 of VGLL1, resulting in the formation of a putative chimeric protein with the N-terminal transcriptional activation domain (TAD) of EWSR1 and C-terminal full length of the VGLL1 protein. Carbon 286-287 vestigial like family member 1 Homo sapiens 148-153 31697442-5 2020 Next-generation RNA sequencing identified a novel fusion transcript, in which the in-frame junctional reads contained exon 9 of EWSR1 and exon 2 of VGLL1, resulting in the formation of a putative chimeric protein with the N-terminal transcriptional activation domain (TAD) of EWSR1 and C-terminal full length of the VGLL1 protein. Carbon 286-287 EWS RNA binding protein 1 Homo sapiens 276-281 31697442-5 2020 Next-generation RNA sequencing identified a novel fusion transcript, in which the in-frame junctional reads contained exon 9 of EWSR1 and exon 2 of VGLL1, resulting in the formation of a putative chimeric protein with the N-terminal transcriptional activation domain (TAD) of EWSR1 and C-terminal full length of the VGLL1 protein. Carbon 286-287 vestigial like family member 1 Homo sapiens 316-321 32180630-0 2020 Development of amperometric biosensor in modified carbon paste with enzymatic preparation based on lactase immobilized on carbon nanotubes. Carbon 50-56 lactase Homo sapiens 99-106 32180630-0 2020 Development of amperometric biosensor in modified carbon paste with enzymatic preparation based on lactase immobilized on carbon nanotubes. Carbon 122-128 lactase Homo sapiens 99-106 32180630-2 2020 Thus, in this work an efficient and minimally invasive method for the detection of lactose was proposed, using a biosensor containing the enzyme lactase (LAC) immobilised on carbon nanotubes (CNTs) that, when reacting with lactose, emit an electrochemical signal. Carbon 174-180 lactase Homo sapiens 145-152 32180630-2 2020 Thus, in this work an efficient and minimally invasive method for the detection of lactose was proposed, using a biosensor containing the enzyme lactase (LAC) immobilised on carbon nanotubes (CNTs) that, when reacting with lactose, emit an electrochemical signal. Carbon 174-180 lactase Homo sapiens 154-157 31919735-0 2020 Correction to: Phosphomimetic Mutation of Glycine Transporter GlyT1 C-Terminal PDZ Binding Motif Inhibits its Interactions with PSD95. Carbon 0-1 discs large MAGUK scaffold protein 4 Homo sapiens 128-133 32182407-0 2020 Multidimension-Controllable Synthesis of MOF-Derived Co@N-Doped Carbon Composite with Magnetic-Dielectric Synergy toward Strong Microwave Absorption. Carbon 64-70 lysine acetyltransferase 8 Homo sapiens 41-44 32182407-2 2020 Herein, by controlling the solvent and mole ratio of cobalt/linker, multidimension-controllable MOF-derived nitrogen-doped carbon materials exhibit tunable morphology from sheet-, flower-, cube-, dodecahedron- to octahedron-like. Carbon 123-129 lysine acetyltransferase 8 Homo sapiens 96-99 32182407-3 2020 Tunable electromagnetic parameters of Co@N-doped carbon composites (Co@NC) can be obtained and the initial MOF precursor determines the distribution of carbon framework and magnetic cobalt nanoparticles. Carbon 49-55 lysine acetyltransferase 8 Homo sapiens 107-110 32182407-3 2020 Tunable electromagnetic parameters of Co@N-doped carbon composites (Co@NC) can be obtained and the initial MOF precursor determines the distribution of carbon framework and magnetic cobalt nanoparticles. Carbon 152-158 lysine acetyltransferase 8 Homo sapiens 107-110 31955562-9 2020 Among patients seropositive for hepatitis B or C, IgAN (28.3% and 21.4%, respectively) was the most common cause. Carbon 47-48 IGAN1 Homo sapiens 50-54 31825903-0 2020 Highly dispersive Pt-Pd nanoparticles on graphene oxide sheathed carbon fiber microelectrodes for electrochemical detection of H2O2 released from living cells. Carbon 65-71 protein tyrosine phosphatase receptor type D Homo sapiens 18-23 31825903-1 2020 We report a facile strategy for the synthesis of surfactant-free, small and highly dispersive Pt-Pd nanoparticles on graphene oxide (Pt-Pd NPs/GO) by electroless deposition method, which is sheathed on carbon fiber microelectrodes (CFMs) as an electrochemical sensing platform for highly sensitive and selective detection of hydrogen peroxide (H2O2) released from the living cells. Carbon 202-208 protein tyrosine phosphatase receptor type D Homo sapiens 94-99 31825903-1 2020 We report a facile strategy for the synthesis of surfactant-free, small and highly dispersive Pt-Pd nanoparticles on graphene oxide (Pt-Pd NPs/GO) by electroless deposition method, which is sheathed on carbon fiber microelectrodes (CFMs) as an electrochemical sensing platform for highly sensitive and selective detection of hydrogen peroxide (H2O2) released from the living cells. Carbon 202-208 protein tyrosine phosphatase receptor type D Homo sapiens 133-138 32125329-0 2020 Protein corona formation of human serum albumin with carbon quantum dots from roast salmon. Carbon 53-59 albumin Mus musculus 34-47 32125329-2 2020 In this study, the protein corona formation of carbon quantum dots (CQDs) from roast salmon with human serum albumin (HSA) was explored. Carbon 47-53 albumin Mus musculus 103-116 32064875-1 2020 Singly charged clusters [C+A-]nC+ or [C+A-]nA- of two salts [C+A-] are produced by electrospray ionization of alcohol solutions of the ionic liquids 1-ethyl-3-methylimidazolium tris(pentafluoroethyl)trifluorophosphate (EMI-FAP) and 1,2-Dimethyl-3-propylimidazolium-Methide (EMI-Me). Carbon 24-32 fibroblast activation protein alpha Homo sapiens 223-226 32188449-6 2020 DAF-12 and AAK-2 separately promote a shift in the molar ratios between competing enzymes at two key branch points within the central carbon metabolic pathway diverting carbon atoms from the TCA cycle and directing them to gluconeogenesis. Carbon 134-140 5'-AMP-activated protein kinase catalytic subunit alpha-2 Caenorhabditis elegans 11-16 32188449-6 2020 DAF-12 and AAK-2 separately promote a shift in the molar ratios between competing enzymes at two key branch points within the central carbon metabolic pathway diverting carbon atoms from the TCA cycle and directing them to gluconeogenesis. Carbon 169-175 5'-AMP-activated protein kinase catalytic subunit alpha-2 Caenorhabditis elegans 11-16 32096626-4 2020 Moreover, attributed to the hierarchical hollow structure, which can provide a large surface area, and the improved electric conductivity with a coating of the N/S co-doped carbon layer, which can facilitate charge transport during the catalytic processes, a remarkable OER activity over HNHR@N/S-C with a low overpotential (eta) of 285 mV (at j = 10 mA cm-2) and a Tafel slope of 53.0 mV decade-1 has been achieved, which is comparable to that of the noble metal catalyst IrO2. Carbon 173-179 endothelin receptor type A Homo sapiens 325-328 31967944-3 2020 The direct interaction is mediated through the C-terminal tails of both Dyn2 and alpha-actinin 4, and these proteins interact at invasive structures at the plasma membrane. Carbon 47-48 actinin alpha 4 Homo sapiens 81-96 32170173-10 2020 Among all the treatments, N S treatment effectively increased the organic carbon storage in the 0-60 cm soil layer, which was 54.3 t/hm2. Carbon 76-82 Putative anthocyanidin reductase Zea mays 135-138 32039429-4 2020 In this review, the current progress of MOF-derived carbon-based materials for ORR/OER/HER electrocatalysis is presented. Carbon 52-58 lysine acetyltransferase 8 Homo sapiens 40-43 32039429-5 2020 Materials design strategies of MOF-derived carbon-based materials are firstly summarized to show the rich possibilities of the morphology and composition of MOF-derived carbon-based materials. Carbon 43-49 lysine acetyltransferase 8 Homo sapiens 31-34 32039429-5 2020 Materials design strategies of MOF-derived carbon-based materials are firstly summarized to show the rich possibilities of the morphology and composition of MOF-derived carbon-based materials. Carbon 43-49 lysine acetyltransferase 8 Homo sapiens 157-160 32039429-5 2020 Materials design strategies of MOF-derived carbon-based materials are firstly summarized to show the rich possibilities of the morphology and composition of MOF-derived carbon-based materials. Carbon 169-175 lysine acetyltransferase 8 Homo sapiens 31-34 32039429-5 2020 Materials design strategies of MOF-derived carbon-based materials are firstly summarized to show the rich possibilities of the morphology and composition of MOF-derived carbon-based materials. Carbon 169-175 lysine acetyltransferase 8 Homo sapiens 157-160 32039429-6 2020 A wide range of applications based on these materials for ORR, OER, HER and multifunctional electrocatalysis are discussed, with an emphasis on the required features of MOF-derived carbon-based materials for the electrocatalysis of corresponding reactions. Carbon 181-187 lysine acetyltransferase 8 Homo sapiens 169-172 32039429-7 2020 Finally, perspectives on the development of MOF-derived carbon-based materials for ORR, OER and HER electrocatalysis are provided. Carbon 56-62 lysine acetyltransferase 8 Homo sapiens 44-47 31663123-9 2020 Patients with the C(+) IL-33 11877 SNP had lower ST2 serum concentrations than patients with the C(-) 11877 SNP (P = 0.043). Carbon 18-22 interleukin 33 Homo sapiens 23-28 31927202-4 2020 Sequence analysis revealed that the predicted barbel steed MOSPD2 protein contained an N-terminal extracellular portion composed of a CRAL-TRIO domain, a motile sperm domain, and a transmembrane domain, as well as a short C-terminal intracellular domain. Carbon 134-135 motile sperm domain containing 2 Homo sapiens 59-65 31823020-5 2020 We further found that AMP1 plays an important role for stomatal development, guard cell functioning, and carbon assimilation. Carbon 105-111 Peptidase M28 family protein Arabidopsis thaliana 22-26 32073019-6 2020 The intrinsic biocompatibility of alpha-PC, which is distinct from several other widely studied nanomaterials, such as carbon nanotubes, graphene and MoS2, makes it a promising candidate in functional biomedical applications. Carbon 119-125 APC regulator of WNT signaling pathway Homo sapiens 34-42 32131040-4 2020 Meanwhile, the mesoporous carbon was formed, with the BET specific surface area up to 514.66 m2/g, and pore diameter mainly focused at 3-8 nm. Carbon 26-32 delta/notch like EGF repeat containing Homo sapiens 54-57 31970984-0 2020 High-affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-terminal Proline-rich Domain of SOS1. Carbon 69-70 SOS Ras/Rac guanine nucleotide exchange factor 1 Homo sapiens 103-107 31845388-3 2020 The unique sp/sp2 carbon-conjugated TA-BGY possesses an extended porous network structure with a BET surface area of approximately 300 m2 g-1 . Carbon 18-24 delta/notch like EGF repeat containing Homo sapiens 97-100 31940170-3 2020 The obtained Ni3N/NF displays a high HER activity with a small overpotential of 44 mV and a low Tafel slope of 46 mV dec-1, which is competitive to Pt/C catalyst. Carbon 151-152 deleted in esophageal cancer 1 Homo sapiens 117-122 31844913-1 2020 A novel fed-batch strategy based on carbon/nitrogen (C/N) ratio in a microbial co-culture production medium broth was carried out in a biocalorimeter for improved production of poly (3-hydroxybutyrate) (PHB). Carbon 36-42 prohibitin 1 Homo sapiens 203-206 28784627-7 2017 Integrative metabolomic and genomic profiling further identified one-carbon metabolism as a central node in mTORC1-dependent myelopoiesis. Carbon 69-75 CREB regulated transcription coactivator 1 Mus musculus 108-114 31844913-1 2020 A novel fed-batch strategy based on carbon/nitrogen (C/N) ratio in a microbial co-culture production medium broth was carried out in a biocalorimeter for improved production of poly (3-hydroxybutyrate) (PHB). Carbon 53-54 prohibitin 1 Homo sapiens 203-206 28648976-10 2017 Loading of BM cells with poly(I:C), EAC lysate or hTERT-mRNA could induce the expression of CD11b and CD11c. Carbon 32-33 integrin alpha X Mus musculus 102-107 31672541-0 2020 A C-terminal peptide of TFPI-1 facilitates cytosolic delivery of nucleic acid cargo into mammalian cells. Carbon 2-3 tissue factor pathway inhibitor Homo sapiens 24-30 28932081-8 2017 In the current study, we showed that EGCG treatment significantly increased the poly I:C-induced expression of Toll-like receptor 3 (TLR3), retinoic acid-inducible gene I, and IFN-lambda1 in JFH-1-Huh7 cells. Carbon 39-40 toll like receptor 3 Homo sapiens 111-131 28932081-8 2017 In the current study, we showed that EGCG treatment significantly increased the poly I:C-induced expression of Toll-like receptor 3 (TLR3), retinoic acid-inducible gene I, and IFN-lambda1 in JFH-1-Huh7 cells. Carbon 39-40 toll like receptor 3 Homo sapiens 133-137 31821485-3 2020 The current study investigates the importance of the two isoenzymes of pyruvate carboxylase (PYC1 and PYC2) and one of the key enzymes of the glyoxylate cycle (ICL1) for growth on glycerol (C3) as a sole carbon source. Carbon 204-210 isocitrate lyase 1 Saccharomyces cerevisiae S288C 160-164 28932081-8 2017 In the current study, we showed that EGCG treatment significantly increased the poly I:C-induced expression of Toll-like receptor 3 (TLR3), retinoic acid-inducible gene I, and IFN-lambda1 in JFH-1-Huh7 cells. Carbon 39-40 interferon lambda 1 Homo sapiens 176-187 27086952-3 2017 Polyriboinosinic:polyribocytidylic acid (poly (I:C)), a synthetic analog of viral RNA, induces a Toll-like receptor 3 (TLR3)-dependent arteriolar thrombosis without significant thrombus formation in venules in vivo. Carbon 49-50 toll like receptor 3 Homo sapiens 97-117 27086952-3 2017 Polyriboinosinic:polyribocytidylic acid (poly (I:C)), a synthetic analog of viral RNA, induces a Toll-like receptor 3 (TLR3)-dependent arteriolar thrombosis without significant thrombus formation in venules in vivo. Carbon 49-50 toll like receptor 3 Homo sapiens 119-123 31841694-4 2020 Sequence analysis indicated that Lc-TRAF3 is conserved in vertebrates, constituted with a N-terminal RING finger, two TRAF-type zinc fingers, and a C-terminal TRAF-MATH domain. Carbon 148-149 TNF receptor-associated factor 3 Larimichthys crocea 36-41 28617247-5 2017 During electrochemical measurements, the peapod-like Cu2S/C shows enhanced electrocatalytic activity with a low overpotential of 401 mV at the current density of 10 mA cm-2 and a Tafel slope of 52 mV dec-1. Carbon 53-54 deleted in esophageal cancer 1 Homo sapiens 200-205 31841694-7 2020 Expression analysis revealed that Lc-TRAF3 was broadly distributed in examined organs/tissues, with the highest expression level in gill and weakest in brain, and could be up-regulated under poly I:C, LPS, PGN, and Pseudomonas plecoglossicida stimulation in vivo. Carbon 198-199 TNF receptor-associated factor 3 Larimichthys crocea 37-42 29024465-4 2017 The integrated NC/NiMo/NiMoOx array exhibits an overpotential of 29 mV at 10 mA cm-2 and a low Tafel slope of 46 mV dec-1 for HER due to the abundant active sites, fast electron transport, low charge-transfer resistance, unique architectural structure and synergistic effect of carbon sheath, nanoalloys, and oxides. Carbon 278-284 deleted in esophageal cancer 1 Homo sapiens 116-121 31846774-6 2020 Moreover, the expression levels of OnIRAK1 and OnIRAK4 were clearly altered in all five tissues after Streptococcus agalactiae infection in vivo and could be induced by LPS, Poly I: C, S. agalactiae WC1535 and CPS in Nile tilapia macrophages. Carbon 182-183 interleukin-1 receptor-associated kinase 1 Oreochromis niloticus 35-42 32211095-3 2020 We profiled the expression alterations of TLR3 and LMP1 within these NPC cell lines in response to poly (I:C) treatment, and found a high correlation between them ws found, suggesting potential involvement of TLR3 in LMP1 signaling. Carbon 71-72 toll like receptor 3 Homo sapiens 42-46 29185453-0 2017 Dysregulation of YAP by ARF Stimulated with Tea-derived Carbon Nanodots. Carbon 56-62 yes-associated protein 1 Mus musculus 17-20 29185453-7 2017 Moreover, we found tea-derived carbon dots can interact with ARF in nucleus that may further lead to the non-nuclear localization of YAP. Carbon 31-37 yes-associated protein 1 Mus musculus 133-136 28742967-4 2017 The trifluorotoluene complex is shown to be a synthetic precursor to functionalized cyclohexadienes: In solution, it selectively protonates at the ortho position, and the resulting eta2-arenium species undergoes reactions with nucleophiles at the adjacent meta carbon. Carbon 261-267 DNA polymerase iota Homo sapiens 181-185 32211095-3 2020 We profiled the expression alterations of TLR3 and LMP1 within these NPC cell lines in response to poly (I:C) treatment, and found a high correlation between them ws found, suggesting potential involvement of TLR3 in LMP1 signaling. Carbon 71-72 toll like receptor 3 Homo sapiens 209-213 31399795-1 2020 BACKGROUND: Activated carbon nanoparticle (CNP) is a novel tracer that may facilitate nodal dissection in clinically nodal positive (cN1) papillary thyroid carcinoma (PTC). Carbon 22-28 5'-nucleotidase, cytosolic IA Homo sapiens 133-136 28779072-4 2017 The obtained bamboo shoot-derived carbons possessed a large BET surface area (up to 972 m2 g-1), hierarchically interconnected porous framework, rich and uniform nitrogen incorporation (3.0 at%). Carbon 34-41 delta/notch like EGF repeat containing Homo sapiens 60-63 28651203-5 2017 Lithium-ion battery devices based on the carbon-coated ZnO mat passivation by atomic layer deposited HfO2 exhibit an excellent initial discharge and charge capacities of 2684.01 and 963.21mAhg-1, respectively, at a current density of 100mAg-1 in the voltage range of 0.01-3V. Carbon 41-47 dentin matrix protein 1 Mus musculus 237-242 28811146-1 2017 The carbon-nitrogen ratio (COD/NH4+-N) is an important factor affecting nitrification and denitrification in wastewater treatment; this factor also influences nitrous oxide (N2O) emissions. Carbon 4-10 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 27-30 32001713-6 2020 As a result, the carbon doped NiO catalyst achieves an ultralow overpotential of 27 mV at 10 mA cm-2, and a low Tafel slope of 36 mV dec-1, representing the best performance among the state-of-the-art NiO catalysts. Carbon 17-23 deleted in esophageal cancer 1 Homo sapiens 133-138 29629084-7 2018 Functionalization of Mg2(pc-dobpdc) with large diamines such as N-(n-heptyl)ethylenediamine results in optimal adsorption behavior, highlighting the advantage of tuning both the pore shape and the diamine size for the development of new adsorbents for carbon capture applications. Carbon 252-258 mucin 7, secreted Homo sapiens 28-34 28726400-4 2017 Molecular docking studies of 1 and 2 with human maltase-glucoamylase (MGAM) were performed for the first time; thus, the 2,3-diH+-1H-1,2,3-triazolium cation (2i) showed good interactions with both MGAM-N (2QMJ) and -C (3TOP) terminal subunits. Carbon 216-217 maltase-glucoamylase Homo sapiens 48-68 28726400-4 2017 Molecular docking studies of 1 and 2 with human maltase-glucoamylase (MGAM) were performed for the first time; thus, the 2,3-diH+-1H-1,2,3-triazolium cation (2i) showed good interactions with both MGAM-N (2QMJ) and -C (3TOP) terminal subunits. Carbon 216-217 maltase-glucoamylase Homo sapiens 70-74 31742998-1 2020 Enantiomer level isolation of single-wall carbon nanotubes (SWCNTs) in high concentration and purity for nanotubes greater than 1.1 nm in diameter is demonstrated using a two-stage aqueous two-phase extraction (ATPE) technique. Carbon 42-48 ATP synthase F1 subunit epsilon Homo sapiens 211-215 28948774-0 2017 (101) Plane-Oriented SnS2 Nanoplates with Carbon Coating: A High-Rate and Cycle-Stable Anode Material for Lithium Ion Batteries. Carbon 42-48 sodium voltage-gated channel alpha subunit 11 Homo sapiens 21-25 31915781-5 2020 Computational results (MP2/aug-cc-pVDZ) reproduce this observation and allow one to conclude that the increase of 1JCH is mainly caused by the change of the carbon hybridization (an increase of s-character), rather than by the change in interatomic distance rCH. Carbon 157-163 joining chain of multimeric IgA and IgM Homo sapiens 115-118 28970524-1 2017 Carbon nanotubes (CTNs) with large aspect-ratios are extensively used to establish electrical connectedness in polymer melts at very low CNT loadings. Carbon 0-6 cystinosin, lysosomal cystine transporter Homo sapiens 18-22 28900512-0 2017 Aptavalve-gated Mesoporous Carbon Nanospheres image Cellular Mucin and provide On-demand Targeted Drug Delivery. Carbon 27-33 LOC100508689 Homo sapiens 61-66 28740108-4 2017 This may be attributed to a weak neuraminidase (NA) cleavage of carbon-6-linked sialic acid (Sia) rather than carbon-3-linked Sia. Carbon 64-70 neuraminidase 1 Homo sapiens 33-46 31840729-5 2020 This st14 inhibitor was fabricated by conjugating a recombinant st14 inhibitor (KD1) with carbon quantum dots (CQDs). Carbon 90-96 suppression of tumorigenicity 14 (colon carcinoma) Mus musculus 5-9 28709900-0 2017 Development of carbon-graphene-based aptamer biosensor for EN2 protein detection. Carbon 15-21 engrailed homeobox 2 Homo sapiens 59-62 27371805-5 2017 The interaction of SWCNT+STX induced a decrease in cell viability. Carbon 19-24 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 Mus musculus 25-28 31840729-5 2020 This st14 inhibitor was fabricated by conjugating a recombinant st14 inhibitor (KD1) with carbon quantum dots (CQDs). Carbon 90-96 suppression of tumorigenicity 14 (colon carcinoma) Mus musculus 64-68 27371805-7 2017 Treatment with SWCNT-COOH induced high reactive oxygen species levels, an effect attenuated in SWCNT-COOH+STX treatment. Carbon 15-20 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 Mus musculus 106-109 31968547-3 2020 In order to solve this problem, we use a cage like microporous MOF(CPM-5) as a carbon source, which is carbonized at high temperature to get a micro-mesoporous carbon composite material. Carbon 79-85 lysine acetyltransferase 8 Homo sapiens 63-66 31968547-3 2020 In order to solve this problem, we use a cage like microporous MOF(CPM-5) as a carbon source, which is carbonized at high temperature to get a micro-mesoporous carbon composite material. Carbon 103-109 lysine acetyltransferase 8 Homo sapiens 63-66 31694937-5 2020 Interactions with FXR family members are mediated by the C-terminal repeating peptide of HVD. Carbon 57-58 nuclear receptor subfamily 1 group H member 4 Homo sapiens 18-21 31966645-0 2017 Expression of toll-like receptor 2, 4 and related cytokines in intraperitoneally inoculated Balb/C mice with Echinococcus multilocularis. Carbon 97-98 toll-like receptor 2 Mus musculus 14-37 28983294-4 2017 A synthetic analog of viral double-stranded RNA, poly I:C, dose-dependently induced IL-8 production at the mRNA and protein levels in IPEC-J2 cells. Carbon 56-57 C-X-C motif chemokine ligand 8 Sus scrofa 84-88 28983294-6 2017 Compared with LTAs from other probiotic Lactobacillus strains including L. delbrueckii, L. sakei, and L. rhamnosus GG, Lp.LTA had higher potential to suppress poly I:C-induced IL-8 production. Carbon 0-1 C-X-C motif chemokine ligand 8 Sus scrofa 176-180 31940100-0 2020 New Immunosensing-Fluorescence Detection of Tumor Marker Cytokeratin-19 Fragment (CYFRA 21-1) Via Carbon Quantum Dots/Zinc Oxide Nanocomposite. Carbon 98-104 keratin 19 Homo sapiens 57-71 28655749-4 2017 Complementation tests in the polyprenol-deficient yeast rer2 mutant and enzyme assays with recombinant AtCPT7 confirmed that the enzyme synthesizes polyprenols of ~55 carbons in length using geranylgeranyl diphosphate (GGPP) and isopentenyl diphosphate as substrates. Carbon 168-175 ditrans,polycis-polyprenyl diphosphate synthase Saccharomyces cerevisiae S288C 57-61 31909713-4 2020 Drg1-ATPase activity removes Rlp24 from the GTPase Nog1 on the pre-60S; consequently, the C-terminal tail of Nog1 is extracted from the PET. Carbon 90-91 dynein axonemal heavy chain 8 Homo sapiens 5-11 28637853-2 2017 By measuring the stable carbon isotopic composition (delta13C values) of particulate organic matter, Chironomidae and Daphnia spp. Carbon 24-30 histocompatibility minor 13 Homo sapiens 126-129 31909713-4 2020 Drg1-ATPase activity removes Rlp24 from the GTPase Nog1 on the pre-60S; consequently, the C-terminal tail of Nog1 is extracted from the PET. Carbon 90-91 ribosomal L24 domain containing 1 Homo sapiens 29-34 31834795-4 2020 (2) B undergoes 1,2-acyl migration from the platinum to the cyclometalated carbon through a three-membered platinacycle transition state to give Pt-arene eta2-complex E with an energy barrier of 14.0 kcal/mol. Carbon 75-81 DNA polymerase iota Homo sapiens 154-158 28533178-4 2017 Variation in adhesion to HT29-cells and mucin was associated with carbon source and mucin-induced subproteome abundancy differences. Carbon 66-72 LOC100508689 Homo sapiens 40-45 32754006-7 2020 Conclusions: An activated carbon impregnated face mask offers a solution for the orthopedic surgeon and supporting personnel who wish to limit their exposure to MMA vapors due to health concerns.Level of Evidence: III. Carbon 26-32 NCK interacting protein with SH3 domain Homo sapiens 129-133 31742890-10 2020 In addition, inhibition of AMPK by employing compound C (an AMPK inhibitor) or AMPK1alpha siRNA significantly suppressed SIRT3 expression, suggesting that AMPK was an up-stream protein of SIRT3 in liver fibrosis. Carbon 54-55 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 27-31 28463517-0 2017 Low-Temperature Carbon Coating of Nanosized Li1.015Al0.06Mn1.925O4 and High-Density Electrode for High-Power Li-Ion Batteries. Carbon 16-22 transglutaminase 1 Homo sapiens 44-47 31791492-5 2020 Moreover, 1 mug/mL to 10 mug/mL carbon particle treatments disrupted the keratinocyte differentiation, and up-regulated inflammation- and psoriasis-related genes, such as IL-1beta, IL-6, CXCL1, CXCL2, CXCL3, CCL20, CXCL8, and S100A7 and S100A9, respectively. Carbon 32-38 C-C motif chemokine ligand 20 Homo sapiens 208-213 31746429-8 2020 Consequently, a novel missense ATRX mutation was identified comprising a single nucleotide change of C to T, which caused an amino acid substitution at codon 172 in exon 7 (c.515C>T; p.Thr172Ile) of the proband. Carbon 0-1 ATRX chromatin remodeler Homo sapiens 31-35 28389557-5 2017 In the GI tract, the microbiota express beta-glucuronidase enzymes that remove the glucuronic acid as a carbon source, effectively reversing the actions of mammalian inactivation. Carbon 104-110 glucuronidase beta Homo sapiens 40-58 28411188-6 2017 Simultaneously, RKIP enhances the Poly(I:C)-induced interaction between TGF-beta-activated kinase 1 and MAPK kinase 3 (MKK3), thus promoting MKK3/6 and p38 activation. Carbon 41-42 mitogen-activated protein kinase kinase kinase 7 Mus musculus 72-99 28411188-6 2017 Simultaneously, RKIP enhances the Poly(I:C)-induced interaction between TGF-beta-activated kinase 1 and MAPK kinase 3 (MKK3), thus promoting MKK3/6 and p38 activation. Carbon 41-42 mitogen-activated protein kinase 14 Mus musculus 152-155 31614141-8 2019 Compound C (an AMPK inhibitor) and LY294002 (a PI3K inhibitor) markedly reversed the alleviating effect of 10-HDA on the expression of tight junction proteins, indicating that 10-HDA inhibited LPS-induced BBB dysfunction by triggering the activation of the AMPK/PI3K/AKT pathway. Carbon 0-1 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 15-19 31614141-8 2019 Compound C (an AMPK inhibitor) and LY294002 (a PI3K inhibitor) markedly reversed the alleviating effect of 10-HDA on the expression of tight junction proteins, indicating that 10-HDA inhibited LPS-induced BBB dysfunction by triggering the activation of the AMPK/PI3K/AKT pathway. Carbon 0-1 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 257-261 31842334-3 2019 In this study, we focused on the biomolecular interactions between the C-terminal domain of AZ (AZ95-228) and ODC to identify the functional elements of AZ that are essential for binding, inhibiting and degrading ODC, and we also identified the crucial factors governing the differential binding and inhibition ability of AZ isoforms toward ODC. Carbon 71-72 ornithine decarboxylase 1 Homo sapiens 110-113 28322516-2 2017 Herein, ZnO nanoparticles encapsulated into N-doped porous carbon has been rationally prepared by the pyrolysis of a metal-organic framework (MOF) followed by a moderate oxidation treatment. Carbon 59-65 lysine acetyltransferase 8 Homo sapiens 117-146 31642194-3 2019 The achieved composite exhibits superior electrocatalytic performance towards HER, more outstanding than the commercial Pt/C catalyst in the light of nearly zero onset overpotential, an extremely low overpotential of 25 mV to obtain a current density of -10 mA cm -2 , a Tafel slope of 58 mV dec -1 and a good durability for 24 h in 1.0 M KOH. Carbon 123-124 deleted in esophageal cancer 1 Homo sapiens 292-298 27786392-3 2017 Compounds [2](PF6 )4 and [3](PF6 )4 feature exclusively M-carbon bonds making them the first purely organometallic molecular squares. Carbon 58-64 sperm associated antigen 17 Homo sapiens 14-17 27786392-3 2017 Compounds [2](PF6 )4 and [3](PF6 )4 feature exclusively M-carbon bonds making them the first purely organometallic molecular squares. Carbon 58-64 sperm associated antigen 17 Homo sapiens 29-32 31295701-2 2019 An activated protein C aptamer (APC-apt) was covalently immobilized on the surface of a carbon paste electrode modified with gold nanoparticle - chitosan /graphene paste (AuNPs-Chi/Gr). Carbon 88-94 APC regulator of WNT signaling pathway Homo sapiens 32-35 28462003-8 2017 The use of powdered activated carbon resulted in a better assimilation of C3-C5 acid forms, indicating that an enhancement in syntrophic metabolism may have taken place. Carbon 30-36 ADAM metallopeptidase with thrombospondin type 1 motif 1 Homo sapiens 74-79 31798961-5 2019 Glucose carbon fate analysis supported tricarboxylic acid cycle reliance on pyruvate carboxylation, catabolic-state fluxes into acetyl-CoA and succinyl-CoA, and a block in de novo nucleoside phosphate synthesis that was accompanied by reduced mTORC1 signaling. Carbon 8-14 CREB regulated transcription coactivator 1 Mus musculus 243-249 28541935-5 2017 A study of carbon-concentrating mechanism-related gene expression revealed that the levels of mRNAs, such as CAH1, LCIB and HLA3, were significantly downregulated. Carbon 11-17 uncharacterized protein Chlamydomonas reinhardtii 124-128 31682135-4 2019 These mesoporous hollow NCQD captured carbon spheres (NCQD-HCS) show fluorescence quantum yield up to 14.6% under lambdaex = 340 nm. Carbon 38-44 holocarboxylase synthetase Homo sapiens 59-62 31624147-5 2019 The resulting interface involved the Galpha alpha5-helix bound to the concave surface of Ric8A and the Galpha beta-sheet that wraps around the C-terminal part of the Ric8A armadillo domain, leading to a severe disruption of the GDP-binding site. Carbon 143-144 RIC8 guanine nucleotide exchange factor A Homo sapiens 166-171 28314510-0 2017 t-Butyl pyridine and phenyl C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists. Carbon 28-29 transient receptor potential cation channel subfamily V member 1 Homo sapiens 113-118 31624147-6 2019 Further modeling of the flexible C-terminal tail of Ric8A indicated that it interacts with the effector surface of Galpha. Carbon 33-34 RIC8 guanine nucleotide exchange factor A Homo sapiens 52-57 28328229-4 2017 Here, the bonding types generated between a PCE with silyl functionalities (PCE-Sil) and a synthetic calcium silicate hydrate (C-S-H) are analyzed using XRD, 29Si NMR spectroscopy, and synchrotron-based techniques, such as NEXAFS and EXAFS. Carbon 45-46 STIL centriolar assembly protein Homo sapiens 80-83 31661237-5 2019 Thus, the uniquely-formed stable carbon network achieves active hydrogen evolution with a Tafel slope of 39 mV dec^-1 and a double layer capacitance of 12.41 mF cm^-2, which breaks the conventional limit of graphene-based catalysis, suggesting a promising strategy for metal-free catalyst engineering and hydrogen production. Carbon 33-39 deleted in esophageal cancer 1 Homo sapiens 111-117 28225587-14 2017 Minor structural differences such as relative carbon-carbon double bond positions were found in several cases to affect the correct rank of the MoNA annotated metabolite. Carbon 46-52 GRB2 related adaptor protein 2 Homo sapiens 144-148 28225587-14 2017 Minor structural differences such as relative carbon-carbon double bond positions were found in several cases to affect the correct rank of the MoNA annotated metabolite. Carbon 53-59 GRB2 related adaptor protein 2 Homo sapiens 144-148 31756921-3 2019 Four major classes of enzymes that attenuate TCR signaling include E3 ubiquitin kinases such as the Casitas B-lineage lymphoma proteins (Cbl-b and c-Cbl), and Itchy (Itch), inhibitory tyrosine phosphatases, such as Src homology region 2 domain-containing phosphatases (SHP-1 and SHP-2), inhibitory protein kinases, such as C-terminal Src kinase (Csk), and inhibitory lipid kinases such as Src homology 2 (SH2) domain-containing inositol polyphosphate 5-phosphatase (SHIP) and Diacylglycerol kinases (DGKs). Carbon 46-47 C-terminal Src kinase Homo sapiens 346-349 31237394-3 2019 Herein, using on-line differential electrochemical mass spectrometry, we show that oxygen-containing carbon surface groups present on high-surface aera carbon, Vulcan XC72 or reinforced graphite are oxidized at PEMFC anode-relevant potential (E=0.1 V vs. the reversible hydrogen electrode, RHE), but not at E=0.4 V vs. RHE. Carbon 101-107 factor interacting with PAPOLA and CPSF1 Homo sapiens 290-293 28092787-0 2017 Perfect 1JCH-resolved HSQC: Efficient measurement of one-bond proton-carbon coupling constants along the indirect dimension. Carbon 69-75 joining chain of multimeric IgA and IgM Homo sapiens 9-12 31237394-3 2019 Herein, using on-line differential electrochemical mass spectrometry, we show that oxygen-containing carbon surface groups present on high-surface aera carbon, Vulcan XC72 or reinforced graphite are oxidized at PEMFC anode-relevant potential (E=0.1 V vs. the reversible hydrogen electrode, RHE), but not at E=0.4 V vs. RHE. Carbon 101-107 factor interacting with PAPOLA and CPSF1 Homo sapiens 319-322 27878872-3 2017 Here, molecular metal dithiolene-diamine (MS2 N2 , M=Co and Ni), metal bis(dithiolene) (MS4 ), and metal bis(diamine) (MN4 ) complexes were selectively incorporated into carbon-rich 2D metal-organic frameworks (2D MOFs) as model carbon electrocatalysts. Carbon 170-176 MS4 Homo sapiens 88-91 28223796-0 2017 Stromelysin-2 (MMP-10) facilitates clearance and moderates inflammation and cell death following lung exposure to long multiwalled carbon nanotubes. Carbon 131-137 matrix metallopeptidase 10 Mus musculus 0-13 31237394-3 2019 Herein, using on-line differential electrochemical mass spectrometry, we show that oxygen-containing carbon surface groups present on high-surface aera carbon, Vulcan XC72 or reinforced graphite are oxidized at PEMFC anode-relevant potential (E=0.1 V vs. the reversible hydrogen electrode, RHE), but not at E=0.4 V vs. RHE. Carbon 152-158 factor interacting with PAPOLA and CPSF1 Homo sapiens 290-293 31237394-3 2019 Herein, using on-line differential electrochemical mass spectrometry, we show that oxygen-containing carbon surface groups present on high-surface aera carbon, Vulcan XC72 or reinforced graphite are oxidized at PEMFC anode-relevant potential (E=0.1 V vs. the reversible hydrogen electrode, RHE), but not at E=0.4 V vs. RHE. Carbon 152-158 factor interacting with PAPOLA and CPSF1 Homo sapiens 319-322 31690658-6 2019 Second, Pat1 directly activates decapping by binding elements in the disordered C-terminal extension of Dcp2, alleviating autoinhibition and promoting substrate binding. Carbon 80-81 decapping mRNA 2 Homo sapiens 104-108 28223796-0 2017 Stromelysin-2 (MMP-10) facilitates clearance and moderates inflammation and cell death following lung exposure to long multiwalled carbon nanotubes. Carbon 131-137 matrix metallopeptidase 10 Mus musculus 15-21 31602485-2 2019 QKI protein possesses a maxi-KH domain composed of single heterogeneous nuclear ribonucleoprotein K homology (KH) domain and C-terminal QUA2 domain, that binds a sequence-specific QKI RNA recognition element (QRE), CUAAC. Carbon 125-126 QKI, KH domain containing RNA binding Homo sapiens 0-3 31602485-2 2019 QKI protein possesses a maxi-KH domain composed of single heterogeneous nuclear ribonucleoprotein K homology (KH) domain and C-terminal QUA2 domain, that binds a sequence-specific QKI RNA recognition element (QRE), CUAAC. Carbon 125-126 QKI, KH domain containing RNA binding Homo sapiens 180-183 28032945-1 2017 While chemoselectivities in Pd0 -catalyzed coupling reactions are frequently non-intuitive and a result of a complex interplay of ligand/catalyst, substrate, and reaction conditions, we herein report a general method based on PdI that allows for an a priori predictable chemoselective Csp2 -Csp2 coupling at C-Br in preference to C-OTf and C-Cl bonds, regardless of the electronic or steric bias of the substrate. Carbon 285-286 prolyl 4-hydroxylase subunit beta Homo sapiens 226-229 31718088-3 2019 The N-terminal half of CAP has been shown to promote actin filament dynamics by enhancing ADF-/cofilin-mediated actin severing, while the central and C-terminal domains are involved in recharging the depolymerized ADP-G-actin/cofilin complexes with ATP and profilin. Carbon 23-24 destrin, actin depolymerizing factor Homo sapiens 90-93 27909055-4 2017 Functionally identified members of this family phosphorylate 3- to 7-carbon sugars or sugar derivatives, but the endogenous substrate of S. cerevisiae Ydr109c and human FGGY has remained unknown. Carbon 69-75 FGGY carbohydrate kinase domain containing Homo sapiens 169-173 31718088-3 2019 The N-terminal half of CAP has been shown to promote actin filament dynamics by enhancing ADF-/cofilin-mediated actin severing, while the central and C-terminal domains are involved in recharging the depolymerized ADP-G-actin/cofilin complexes with ATP and profilin. Carbon 23-24 cofilin 1 Homo sapiens 95-102 31718088-3 2019 The N-terminal half of CAP has been shown to promote actin filament dynamics by enhancing ADF-/cofilin-mediated actin severing, while the central and C-terminal domains are involved in recharging the depolymerized ADP-G-actin/cofilin complexes with ATP and profilin. Carbon 23-24 cofilin 1 Homo sapiens 226-233 28050615-4 2017 Specifically, when the pine needle-derived carbon (activated at 800 C) serves as a HER electrocatalyst, it exhibits a low onset potential (~4 mV), a small Tafel slope (~45.9 mV dec-1) and a remarkable stability over long-term cycling. Carbon 43-49 deleted in esophageal cancer 1 Homo sapiens 178-183 31570524-0 2019 The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion. Carbon 4-5 LOC100508689 Homo sapiens 54-59 27769942-0 2017 Carbon nanotube-composite hydrogels promote intercalated disc assembly in engineered cardiac tissues through beta1-integrin mediated FAK and RhoA pathway. Carbon 0-6 protein tyrosine kinase 2 Homo sapiens 133-136 27721076-1 2017 This paper presents the results of the application of the advanced LBET and QSDFT methods compared to the BET and DR approach to the comprehensive analysis of the porous structure of activated carbons obtained by chemical activation of demineralised Kraft lignin with potassium and sodium hydroxides. Carbon 193-200 delta/notch like EGF repeat containing Homo sapiens 68-71 31570524-0 2019 The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion. Carbon 4-5 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 60-65 31570524-0 2019 The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion. Carbon 4-5 LOC100508689 Homo sapiens 79-84 31570524-7 2019 In summary, our results suggest a role for the C-terminal dimerization domain of MUC5B in compaction of mucin chains during granular packaging via interactions with the N-terminal multimerization domain. Carbon 47-48 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 81-86 28928483-3 2017 Here, we demonstrate that ArcA overexpression in aerobic conditions, results in downregulation of respiratory pathways and enhanced growth rates on glycolytic substrates of E. coli, coinciding with acetate excretion and increased carbon uptake rates. Carbon 230-236 arginine deiminase Escherichia coli 26-30 31570524-7 2019 In summary, our results suggest a role for the C-terminal dimerization domain of MUC5B in compaction of mucin chains during granular packaging via interactions with the N-terminal multimerization domain. Carbon 47-48 LOC100508689 Homo sapiens 104-109 31956425-0 2020 Wood-Derived Carbon Fibers Embedded with SnO x Nanoparticles as Anode Material for Lithium-Ion Batteries. Carbon 13-19 strawberry notch homolog 1 Homo sapiens 41-44 28878165-5 2017 Strong inhibition of &#945;-lipoamide dehydrogenase was also noted for the VPA one-carbon homolog sec -butylpropylacetic acid (SPA) and to a lesser extent for the VPA constitutional isomer valnoctic acid (VCA), while the corresponding amides of the above three acids valpromide (VPD), sec -butylpropylacetamide (SPD) and valnoctamide (VCD) showed only small effects. Carbon 87-93 dihydrolipoamide dehydrogenase Homo sapiens 32-55 28794328-2 2017 In this paper, by preparing poly(L-arginine) modified glassy carbon electrode (P-L-Arg/GCE) with a simple method, a highly sensitive electrochemical sensor for simultaneously detecting HQ, CC and RS was constructed successfully due to the large surface area, good electronic properties and catalytic ability of P-L-Arg/GCE and the electrostatic action between P-L-Arg (positive) and targets (negative). Carbon 61-67 glycine decarboxylase Homo sapiens 79-90 28794328-2 2017 In this paper, by preparing poly(L-arginine) modified glassy carbon electrode (P-L-Arg/GCE) with a simple method, a highly sensitive electrochemical sensor for simultaneously detecting HQ, CC and RS was constructed successfully due to the large surface area, good electronic properties and catalytic ability of P-L-Arg/GCE and the electrostatic action between P-L-Arg (positive) and targets (negative). Carbon 61-67 glycine decarboxylase Homo sapiens 311-322 27876249-3 2017 Our data confirms that naphthylmethyl substituents at the nitrogen atoms (N1(N3)) and highly lipophilic substituents at the carbon atoms (C2 and C5(C6)) can generate benzimidazolium salts with anti-proliferative activity that is comparable to that of cisplatin. Carbon 124-130 complement C6 Homo sapiens 145-151 31956425-1 2020 Carbon-SnO x composites are obtained by impregnating acetylacetone-treated, delignified wood fibers with tin precursor and successively carbonizing at 1000 C in 95% argon and 5% oxygen. Carbon 0-6 strawberry notch homolog 1 Homo sapiens 7-10 28544901-2 2017 The highly graphitized multi-walled carbon nanotubes g-MWCNTs modified electrode was prepared for the in-situ electrochemical generation of HO2-. Carbon 36-42 heme oxygenase 2 Homo sapiens 140-143 31956425-5 2020 The resultant carbon-SnO x material with 16 wt% SnO x shows excellent electrochemical performance of rate capability from 0.1 to 10 A g-1 and cycling stability for 1000 cycles with Li-ion storage capacity of 280 mAh g-1 at a current density of 10 A g-1. Carbon 14-20 strawberry notch homolog 1 Homo sapiens 21-24 31956425-5 2020 The resultant carbon-SnO x material with 16 wt% SnO x shows excellent electrochemical performance of rate capability from 0.1 to 10 A g-1 and cycling stability for 1000 cycles with Li-ion storage capacity of 280 mAh g-1 at a current density of 10 A g-1. Carbon 14-20 strawberry notch homolog 1 Homo sapiens 48-51 31956425-6 2020 The remarkable electrochemical performance of wood-derived carbon-SnO x composite is attributed to the reproduction of structural featured wood fibers to nanoscale in carbon-SnO x composite and controlled passivation of tin nanoparticles to yield SnO x nanoparticles. Carbon 59-65 strawberry notch homolog 1 Homo sapiens 66-69 31956425-6 2020 The remarkable electrochemical performance of wood-derived carbon-SnO x composite is attributed to the reproduction of structural featured wood fibers to nanoscale in carbon-SnO x composite and controlled passivation of tin nanoparticles to yield SnO x nanoparticles. Carbon 59-65 strawberry notch homolog 1 Homo sapiens 174-177 28806682-9 2017 TGA analysis of the photolysed activated carbons in the presence of BSA suggested that ozonized carbon samples underwent insertion of BSA upon photolysis, in particular the sample ozonized under dry conditions. Carbon 41-48 T-box transcription factor 1 Homo sapiens 0-3 31956425-6 2020 The remarkable electrochemical performance of wood-derived carbon-SnO x composite is attributed to the reproduction of structural featured wood fibers to nanoscale in carbon-SnO x composite and controlled passivation of tin nanoparticles to yield SnO x nanoparticles. Carbon 59-65 strawberry notch homolog 1 Homo sapiens 174-177 28806682-9 2017 TGA analysis of the photolysed activated carbons in the presence of BSA suggested that ozonized carbon samples underwent insertion of BSA upon photolysis, in particular the sample ozonized under dry conditions. Carbon 41-47 T-box transcription factor 1 Homo sapiens 0-3 31956425-6 2020 The remarkable electrochemical performance of wood-derived carbon-SnO x composite is attributed to the reproduction of structural featured wood fibers to nanoscale in carbon-SnO x composite and controlled passivation of tin nanoparticles to yield SnO x nanoparticles. Carbon 167-173 strawberry notch homolog 1 Homo sapiens 66-69 31457784-5 2017 The well-tuned carbon-MoS2 composite shows a Tafel slope of 48.9 mV dec-1, an onset potential of -0.079 V (vs reversible hydrogen electrode), and an overpotential of 126 mV at the current density of 10 mA cm-2 after 1000 potential cycles. Carbon 15-21 deleted in esophageal cancer 1 Homo sapiens 68-73 28652544-9 2017 Ghrelin administration decreased the methylation ratio of C-260 of PGC-1alpha in the skeletal muscle and increased the expression. Carbon 58-59 peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus 67-77 31956425-6 2020 The remarkable electrochemical performance of wood-derived carbon-SnO x composite is attributed to the reproduction of structural featured wood fibers to nanoscale in carbon-SnO x composite and controlled passivation of tin nanoparticles to yield SnO x nanoparticles. Carbon 167-173 strawberry notch homolog 1 Homo sapiens 174-177 31956425-6 2020 The remarkable electrochemical performance of wood-derived carbon-SnO x composite is attributed to the reproduction of structural featured wood fibers to nanoscale in carbon-SnO x composite and controlled passivation of tin nanoparticles to yield SnO x nanoparticles. Carbon 167-173 strawberry notch homolog 1 Homo sapiens 174-177 31517402-4 2019 By introducing guest iron (Fe) ions into the core@shell MOF precursor, the open carbon cages are self-assembled into a hydrangea-like 3D superstructure interconnected by carbon nanotubes, which are grown in situ on the Fe-Co alloy nanoparticles formed during the pyrolysis of Fe-introduced Zn@Co-MOFs. Carbon 80-86 lysine acetyltransferase 8 Homo sapiens 56-59 28216894-11 2017 The polar groups at C-1, C-2, C-3, C-23, and C-28 and the linkage of sugar moieties influenced the different cytotoxic activities. Carbon 20-21 nucleolin Homo sapiens 35-39 28671468-7 2017 The dimeric compound with the 10-carbon linker was modestly more effective for the isolated PKCdelta C1b domain than was the monomeric compound. Carbon 33-39 protein kinase C delta Homo sapiens 92-100 28671468-8 2017 For the intact PKCalpha and PKCdelta, the shortest DAG-lactone dimer had similar affinity to the monomer and affinity decreased progressively up to the 16-carbon linker. Carbon 155-161 protein kinase C delta Homo sapiens 28-36 31517402-4 2019 By introducing guest iron (Fe) ions into the core@shell MOF precursor, the open carbon cages are self-assembled into a hydrangea-like 3D superstructure interconnected by carbon nanotubes, which are grown in situ on the Fe-Co alloy nanoparticles formed during the pyrolysis of Fe-introduced Zn@Co-MOFs. Carbon 170-176 lysine acetyltransferase 8 Homo sapiens 56-59 27743864-5 2017 A direct electron transfer type glucose dehydrogenase was immobilized onto mesoporous carbon, and then deposited on the surface of a miniaturized Au electrode (7mm2) to prepare a miniaturized enzyme anode. Carbon 86-92 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 32-53 27387260-2 2016 As graphene-like 2D nanomaterial, SnS2 nanosheets loaded on the conducting framework of multi-walled carbon nanotubes (MWCNTs) were adopted for the construction of immunosensor for the first time, providing a favorable substrate for in-situ growth of CdS nanocrystal that had suitable band structure matching well with SnS2. Carbon 101-107 sodium voltage-gated channel alpha subunit 11 Homo sapiens 34-38 31512136-7 2019 It was found for the first time that the effect of pH on the CO2 absorption ratio was affected by carbon concentration. Carbon 98-104 phenylalanine hydroxylase Homo sapiens 51-53 28500049-5 2017 Here, by comparing differentially expressed genes in dbp2 to those of 700 other deletion strains from other studies, we find that CYC8 and TUP1, which form a complex and inhibit transcription of numerous genes, corepress a common set of genes with DBP2 Gene ontology (GO) annotations reveal that these corepressed genes are related to cellular metabolism, including respiration, gluconeogenesis, and alternative carbon-source utilization genes. Carbon 413-419 DEAD-box ATP-dependent RNA helicase DBP2 Saccharomyces cerevisiae S288C 53-57 28500049-5 2017 Here, by comparing differentially expressed genes in dbp2 to those of 700 other deletion strains from other studies, we find that CYC8 and TUP1, which form a complex and inhibit transcription of numerous genes, corepress a common set of genes with DBP2 Gene ontology (GO) annotations reveal that these corepressed genes are related to cellular metabolism, including respiration, gluconeogenesis, and alternative carbon-source utilization genes. Carbon 413-419 transcription regulator CYC8 Saccharomyces cerevisiae S288C 131-135 28500049-5 2017 Here, by comparing differentially expressed genes in dbp2 to those of 700 other deletion strains from other studies, we find that CYC8 and TUP1, which form a complex and inhibit transcription of numerous genes, corepress a common set of genes with DBP2 Gene ontology (GO) annotations reveal that these corepressed genes are related to cellular metabolism, including respiration, gluconeogenesis, and alternative carbon-source utilization genes. Carbon 413-419 chromatin-silencing transcriptional regulator TUP1 Saccharomyces cerevisiae S288C 140-144 28500049-5 2017 Here, by comparing differentially expressed genes in dbp2 to those of 700 other deletion strains from other studies, we find that CYC8 and TUP1, which form a complex and inhibit transcription of numerous genes, corepress a common set of genes with DBP2 Gene ontology (GO) annotations reveal that these corepressed genes are related to cellular metabolism, including respiration, gluconeogenesis, and alternative carbon-source utilization genes. Carbon 413-419 DEAD-box ATP-dependent RNA helicase DBP2 Saccharomyces cerevisiae S288C 249-253 27960359-5 2016 The BET surface areas of the sulfur-functionalized ordered mesoporous carbons range from 837 to 2865 m2/g with total pore volume of 0.71-2.3 cm3/g. Carbon 70-77 delta/notch like EGF repeat containing Homo sapiens 4-7 31602228-4 2019 In addition, adenosine monophosphate-activated protein kinase (AMPK) inhibitor compound C (CC) was used to inhibit AMPKalpha1 expression. Carbon 88-89 protein kinase AMP-activated catalytic subunit alpha 1 Rattus norvegicus 63-67 31602228-4 2019 In addition, adenosine monophosphate-activated protein kinase (AMPK) inhibitor compound C (CC) was used to inhibit AMPKalpha1 expression. Carbon 88-89 protein kinase AMP-activated catalytic subunit alpha 1 Rattus norvegicus 115-125 28608694-2 2017 These four synthetic models differ mostly by the shape and polarity of their cavities and also possibly by motion of the distal strap attached to two of the meso carbon atoms. Carbon 162-168 serine/threonine kinase receptor associated protein Homo sapiens 128-133 31933800-8 2019 The 1,135 predicted targets of miR-452-5p were enriched in the pathways of cytokine-cytokine receptor interaction, carbon metabolism, and complement and coagulation cascades. Carbon 115-121 MLX interacting protein Homo sapiens 31-34 28512031-3 2017 Replacing this with a C-N bond significantly simplified synthesis, yielding pyrazole analog 35, of which we obtained a co-crystal structure with KDM5A. Carbon 22-23 lysine (K)-specific demethylase 5A Mus musculus 145-150 27067734-5 2016 Specific surface area, pore size diameter, crystallinity, and degree of graphitization of the hollow and mesoporous structures of carbon nanofibers obtained after carbonization of the as spun PMMA/PAN nanofibers were characterized by BET analyses, X-ray diffraction, and Raman spectroscopy in addition to the conductivity measurements. Carbon 130-136 delta/notch like EGF repeat containing Homo sapiens 234-237 27520391-2 2016 Arabidopsis thaliana and other Brassicaceae contain an additional cytosolic fumarase (FUM2) that functions in carbon assimilation and nitrogen use. Carbon 110-116 FUMARASE 2 Arabidopsis thaliana 86-90 31502946-8 2019 Results of growth experiments with TLL-A1T on different carbon sources and analysis of its ~6.5 Gb indicate that TLL-A1T harbours a large gene repertoire that enables it to utilize a variety of carbohydrates for growth. Carbon 56-62 tolloid-like Mus musculus 35-38 27520391-9 2016 Our findings support the role of FUM2 in diurnal carbon storage, and point to a growth advantage of accessions carrying the FUM2 Col-0 allele. Carbon 49-55 FUMARASE 2 Arabidopsis thaliana 33-37 27769479-0 2016 Fluorimetric evaluation of glutathione reductase activity and its inhibitors using carbon quantum dots. Carbon 83-89 glutathione-disulfide reductase Homo sapiens 27-48 27769479-1 2016 A highly sensitive fluorimetric assay has been developed for the evaluation of glutathione reductase (GR) activity and the screening of its inhibitors by using carbon quantum dots (CQDs) as the signal reporter. Carbon 160-166 glutathione-disulfide reductase Homo sapiens 79-100 28533178-13 2017 Increased adhesion was observed following culturing of the bacterium with fructooligosaccharides, cellobiose or polydextrose, as well as mucin-supplemented glucose as carbon source. Carbon 167-173 LOC100508689 Homo sapiens 137-142 28541686-4 2017 The selected MOF crystals act as a single precursor for both nanocatalysts and carbon sources. Carbon 79-85 lysine acetyltransferase 8 Homo sapiens 13-16 27769479-1 2016 A highly sensitive fluorimetric assay has been developed for the evaluation of glutathione reductase (GR) activity and the screening of its inhibitors by using carbon quantum dots (CQDs) as the signal reporter. Carbon 160-166 glutathione-disulfide reductase Homo sapiens 102-104 31502946-8 2019 Results of growth experiments with TLL-A1T on different carbon sources and analysis of its ~6.5 Gb indicate that TLL-A1T harbours a large gene repertoire that enables it to utilize a variety of carbohydrates for growth. Carbon 56-62 tolloid-like Mus musculus 113-116 31672640-2 2019 Alternative mRNA splicing at sites named y and z in the C-terminal part of agrin regulates its interaction with a receptor complex consisting of the agrin-binding protein low-density lipoprotein receptor-related protein 4 (Lrp4) and the tyrosine kinase muscle specific kinase (MuSK). Carbon 56-57 LDL receptor related protein 4 Homo sapiens 171-221 28562055-2 2017 Minimization on the use of protecting groups and redox reactions allowed the synthesis of the carbon backbone of actinoranone in 20 steps (11 steps for LLS). Carbon 94-100 SET domain containing 2, histone lysine methyltransferase Homo sapiens 152-155 27920551-6 2016 Yeast expressing Gat1p and Lpt1p had phospholipids enriched with acyl chains that were unsaturated, 18 carbons long, and paired for length. Carbon 103-110 Gat1p Saccharomyces cerevisiae S288C 17-22 31672640-2 2019 Alternative mRNA splicing at sites named y and z in the C-terminal part of agrin regulates its interaction with a receptor complex consisting of the agrin-binding protein low-density lipoprotein receptor-related protein 4 (Lrp4) and the tyrosine kinase muscle specific kinase (MuSK). Carbon 56-57 LDL receptor related protein 4 Homo sapiens 223-227 31318380-1 2019 The alternative oxidase (AOX) constitutes a nonphosphorylating pathway of electron transport in the mitochondrial respiratory chain that provides flexibility to energy and carbon primary metabolism. Carbon 172-178 alternative oxidase 2 Arabidopsis thaliana 25-28 27841436-3 2016 In crystalline [Li+@C60](PF6-), the Li+ ion rotates in the carbon cage even at 150 K. The rotational mode gradually changes into a librational mode below 120 K, which is associated with the localization of Li+ ions due to the electrostatic interactions with its screening image charge on the C60 cage as well as with the neighboring Li+@C60 and PF6- ions. Carbon 59-65 sperm associated antigen 17 Homo sapiens 25-28 28515149-8 2017 13C-flux analysis showed that Pkm2 deletion reduced the flow of glucose carbons into lactate and glutamate without markedly increasing glucose-to-ribose flux. Carbon 72-79 pyruvate kinase, muscle Mus musculus 30-34 27919823-0 2017 Nerve growth factor-carbon nanotube complex exerts prolonged protective effects in an in vitro model of ischemic stroke. Carbon 20-26 nerve growth factor Rattus norvegicus 0-19 27919823-2 2017 Based on the superior properties of carbon nanotubes (CNTs) for controlled drug delivery, we aimed to prepare CNT-NGF complex and evaluate its effect in an in vitro model of ischemic stroke. Carbon 36-42 nerve growth factor Rattus norvegicus 114-117 27841436-3 2016 In crystalline [Li+@C60](PF6-), the Li+ ion rotates in the carbon cage even at 150 K. The rotational mode gradually changes into a librational mode below 120 K, which is associated with the localization of Li+ ions due to the electrostatic interactions with its screening image charge on the C60 cage as well as with the neighboring Li+@C60 and PF6- ions. Carbon 59-65 sperm associated antigen 17 Homo sapiens 345-348 31318380-1 2019 The alternative oxidase (AOX) constitutes a nonphosphorylating pathway of electron transport in the mitochondrial respiratory chain that provides flexibility to energy and carbon primary metabolism. Carbon 172-178 alternative oxidase 2 Arabidopsis thaliana 4-23 31409699-6 2019 Our results at the transcriptome and at the metabolite analysis level support a model in which WRKY1 enables plants to activate genes involved in the recycling of cellular carbon resources when light is limiting but N is abundant and upregulate amino acid metabolism when both light and N are limiting. Carbon 172-178 zinc-dependent activator protein-1 Arabidopsis thaliana 95-100 27723977-5 2016 d-Biotin was then anchored on the pendant amine rendering alpha-methyne carbon to the biotinamide bond which blocks the biotinidase enzyme activity. Carbon 72-78 biotinidase Mus musculus 120-131 28614715-5 2017 Accordingly, models with high levels of PHGDH display rapid proliferation, migration, and selective channeling of serine-derived carbons to glutathione and pyrimidines, while depletion of PHGDH shows potent and selective toxicity to this subset. Carbon 129-136 phosphoglycerate dehydrogenase Homo sapiens 40-45 28604671-4 2017 Further removing the metal elements from MXenes leads to the formation of all-carbon 2D-2D heterostructures consisting of alternating layers of MXene-derived carbon (MDC) and OMC. Carbon 78-84 C-C motif chemokine ligand 22 Homo sapiens 144-164 31659785-6 2020 Interestingly the HER activity increases with increasing concentration of Pt4+ species in the nanoparticles, and the optimized catalyst even outperforms commercial Pt/C, exhibiting an overpotential of only -7.7 mV to reach the current density of 10 mA cm-2 and a Tafel slope of -26.3 mV dec-1. Carbon 167-168 deleted in esophageal cancer 1 Homo sapiens 287-292 28604671-4 2017 Further removing the metal elements from MXenes leads to the formation of all-carbon 2D-2D heterostructures consisting of alternating layers of MXene-derived carbon (MDC) and OMC. Carbon 78-84 C-C motif chemokine ligand 22 Homo sapiens 166-169 27545980-1 2016 The nucleophilic attack of NHCs on the electron deficient carbon of tetryl substituted phosphaketenes Ph3E-P[double bond, length as m-dash]C[double bond, length as m-dash]O (E = Sn-Si), leads quantitatively to the formation of NHC-phosphaketene adducts. Carbon 58-64 H3 histone pseudogene 26 Homo sapiens 102-106 31641889-2 2019 Herein, a highly active electrocatalyst of nitrogen-doped porous carbon nanosheets coupled with Mo2C nanoparticles (Mo2C/NPC) was synthesized by a novel method with high BET surface area of 1380 m2 g-1 using KOH to activate carbon composite materials. Carbon 65-71 delta/notch like EGF repeat containing Homo sapiens 170-173 27655011-3 2016 The Al=S double bond in 3 can react with phenyl isothiocyanate to furnish the cycloaddition product 9 and zwitterion 10 as a result of coupling between the liberated carbene and PhN=C=S. Carbon 182-183 carbamoyl-phosphate synthase 1 Homo sapiens 178-181 28595626-0 2017 Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-beta1 activation and myofibroblast differentiation. Carbon 34-40 secreted phosphoprotein 1 Mus musculus 0-11 28595626-4 2017 The current study focuses on investigating the role of osteopontin (OPN) in the development of lung fibrosis upon exposure to multi-walled carbon nanotubes (MWCNTs). Carbon 139-145 secreted phosphoprotein 1 Mus musculus 55-66 28595626-4 2017 The current study focuses on investigating the role of osteopontin (OPN) in the development of lung fibrosis upon exposure to multi-walled carbon nanotubes (MWCNTs). Carbon 139-145 secreted phosphoprotein 1 Mus musculus 68-71 31553563-1 2019 The C-terminal domain (CTD) of the largest subunit in eukaryotic RNA polymerase II has a repetitive heptad sequence of Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 which is responsible for recruiting transcriptional regulatory factors. Carbon 4-5 jagged canonical Notch ligand 2 Homo sapiens 124-128 28497772-4 2017 The modification of Fe-incorporated nitrogen-rich-carbons (Fe-CNx) on CNTs lowers the ORR half-wave-potential by ~190 mV, giving this catalyst with an onset ORR potential of 0.95 V (versus reversible hydrogen electrode (RHE)), a half-wave potential of 0.82 V (versus RHE), and the limiting current density of 5.39 mA cm-2 in 0.1 M KOH. Carbon 50-57 calnexin Homo sapiens 62-65 27541683-12 2016 MTHFR C677T and SLC19A1 G80A are the two polymorphisms of one-carbon metabolic pathway that increase breast cancer in the worldwide population. Carbon 62-68 solute carrier family 19 member 1 Homo sapiens 16-23 30964963-2 2019 Herein, the facile synthesis of hierarchically porous carbons through the calcination of metal-organic framework (MOF)/chitosan composites is reported. Carbon 54-61 lysine acetyltransferase 8 Homo sapiens 89-118 27468646-4 2016 CAM treatment led to a significant reduction in poly I:C- and RSV-mediated IL-8, CCL5, IFN-beta and -lambda production. Carbon 0-1 interferon beta 1 Homo sapiens 87-95 28433055-9 2017 Results demonstrate that pyrenyl carbon nanostructures-based FDH bioelectrode design represents novelty and simplicity for enzyme-selective electrochemical quantitation of small 30 Da formaldehyde. Carbon 33-39 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 61-64 30964963-4 2019 The corresponding MOF/chitosan precursors could be readily converted into hierarchically porous carbons (NPC-V, V=1, 2, 4, and 6) with much higher ratios of meso-/macropore volume to micropore volume (Vmeso-macro /Vmicro ). Carbon 96-103 lysine acetyltransferase 8 Homo sapiens 18-21 28362271-3 2017 We present data for carbon ion beams in the energy range from 20 to 400 MeV u-1. Carbon 20-26 RNA, U1 small nuclear 1 Homo sapiens 76-79 30964963-5 2019 The derived carbon NPC-2 with the high ratio of Vmeso-macro /Vmicro =1.47 demonstrates a high specific surface area of 2375 m2 g-1 , and a high pore volume of 2.49 cm3 g-1 , as well as a high graphitization degree, in comparison to its counterpart (NPC) without chitosan addition. Carbon 12-18 NPC intracellular cholesterol transporter 2 Homo sapiens 19-24 28555106-4 2017 The results showed that hepatic CYP2A5 and Nrf2 expression levels were increased in HFD fed mice accompanied with hepatic 18-carbon FA accumulation. Carbon 125-131 cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus 32-38 31597378-0 2019 C-terminal Redox Domain of Arabidopsis APR1 is a Non-Canonical Thioredoxin Domain with Glutaredoxin Function. Carbon 0-1 thioredoxin H-type 1 Arabidopsis thaliana 63-74 28555106-13 2017 It was concluded that HFD-induced hepatic 18-carbon FA accumulation contributes to the up-regulation of CYP2A5/2A6 via activating Nrf2. Carbon 45-51 cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus 104-110 27633574-6 2017 The results illustrated that differences in the levels of phosphorylated H2AX, a double-strand break marker, exist after therapeutic proton and carbon ion irradiations. Carbon 144-150 H2A.X variant histone Homo sapiens 73-77 31597378-4 2019 The crystal structure of the C-terminal redox domain of Arabidopsis APR1 (AtAPR1) shows a conserved alpha/beta thioredoxin fold, but not a glutaredoxin fold. Carbon 29-30 thioredoxin H-type 1 Arabidopsis thaliana 111-122 28074612-1 2017 A ternary CuO-Fe2 O3 -mesocarbon microbeads (MCMB) conversion anode was characterized and combined with a high-voltage Li1.35 Ni0.48 Fe0.1 Mn1.72 O4 spinel cathode in a lithium-ion battery of relevant performance in terms of cycling stability and rate capability. Carbon 45-49 transglutaminase 1 Homo sapiens 119-122 31589600-6 2019 Another large-scale motion was observed for the C-terminal helix alpha13, providing a molecular view for the alpha13-alpha13 distances previously reported for the hGBP1 dimer. Carbon 48-49 guanylate binding protein 1 Homo sapiens 163-168 28211874-5 2017 We show that ATF4 regulates the expression of one-carbon metabolism genes SHMT2 and NMDMC as a protective response to mitochondrial toxicity. Carbon 50-56 Serine hydroxymethyl transferase Drosophila melanogaster 74-79 31595203-5 2019 We found that i) AMPKalpha2 was the predominant catalytic subunit in the subgranular and subventricular zones; ii) AMPK activation was at a significantly higher level in the aged vs. young hippocampus; iii) short term (7 days) treatment with selective AMPK signaling inhibitor Compound C (10 mg/kg/day, i.p.) Carbon 277-278 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 115-119 28271892-5 2017 In N2, C-O-P linkages significantly evolve into C-P-O and C3-P O at up to 800 C, whereas C3-P linkages are not formed even at 900 C. In H2, the corresponding evolution remarkably occurs at 500 C, forming C3-P linkages and eventually elemental phosphorus. Carbon 7-8 translin Homo sapiens 58-64 31807524-15 2019 While carbon-ion has significantly stronger effects on increasing ecto-CRT than proton and photon at 2 and 4 Gy, but changed oppositely at 10 Gy (P<0.05). Carbon 6-12 tripartite motif containing 33 Homo sapiens 66-70 28723213-0 2017 Dual Functional Core-Shell Fluorescent Ag2S@Carbon Nanostructure for Selective Assay of E. coli O157:H7 and Bactericidal Treatment. Carbon 44-50 angiotensin II receptor type 1 Homo sapiens 39-43 28723213-1 2017 A dual functional fluorescent core-shell Ag2S@Carbon nanostructure is prepared by a hydrothermally assisted multi-amino synthesis approach with folic acid (FA), polyethylenimine (PEI), and mannoses (Mans) as carbon and nitrogen sources (FA-PEI-Mans-Ag2S nanocomposite shortly as Ag2S@C). Carbon 46-52 angiotensin II receptor type 1 Homo sapiens 41-45 28723213-1 2017 A dual functional fluorescent core-shell Ag2S@Carbon nanostructure is prepared by a hydrothermally assisted multi-amino synthesis approach with folic acid (FA), polyethylenimine (PEI), and mannoses (Mans) as carbon and nitrogen sources (FA-PEI-Mans-Ag2S nanocomposite shortly as Ag2S@C). Carbon 46-52 angiotensin II receptor type 1 Homo sapiens 249-253 31100207-3 2019 In fed rats, hSTC-1 increases carbon flux from glucose to lipids in retroperitoneal white adipose tissue. Carbon 30-36 stanniocalcin 1 Homo sapiens 13-19 28723213-1 2017 A dual functional fluorescent core-shell Ag2S@Carbon nanostructure is prepared by a hydrothermally assisted multi-amino synthesis approach with folic acid (FA), polyethylenimine (PEI), and mannoses (Mans) as carbon and nitrogen sources (FA-PEI-Mans-Ag2S nanocomposite shortly as Ag2S@C). Carbon 46-52 angiotensin II receptor type 1 Homo sapiens 249-253 28723213-1 2017 A dual functional fluorescent core-shell Ag2S@Carbon nanostructure is prepared by a hydrothermally assisted multi-amino synthesis approach with folic acid (FA), polyethylenimine (PEI), and mannoses (Mans) as carbon and nitrogen sources (FA-PEI-Mans-Ag2S nanocomposite shortly as Ag2S@C). Carbon 208-214 angiotensin II receptor type 1 Homo sapiens 41-45 31330343-0 2019 TAK1 knock-down in macrophage alleviate lung inflammation induced by black carbon and aged black carbon. Carbon 75-81 mitogen-activated protein kinase kinase kinase 7 Mus musculus 0-4 28317858-0 2017 Near-Infrared Photoluminescent Carbon Nanotubes for Imaging of Brown Fat. Carbon 31-37 FAT atypical cadherin 1 Homo sapiens 69-72 31330343-0 2019 TAK1 knock-down in macrophage alleviate lung inflammation induced by black carbon and aged black carbon. Carbon 97-103 mitogen-activated protein kinase kinase kinase 7 Mus musculus 0-4 31581560-6 2019 The results show that the methanogenesis gene, Mcr, was undetected but more carbon fixation genes than nitrate reduction and sulfate genes were found. Carbon 76-82 nuclear receptor subfamily 3 group C member 2 Homo sapiens 47-50 29740996-10 2017 The carbon storage for aboveground and underground parts were 22.80-141.72 t hm-2 and 62.30-102.66 t hm-2, respectively. Carbon 4-10 cholinergic receptor muscarinic 2 Homo sapiens 101-105 28186407-0 2017 X-ray Absorption Spectroscopy Reveals an Organometallic Ni-C Bond in the CO-Treated Form of Acetyl-CoA Synthase. Carbon 59-60 acyl-CoA synthetase short chain family member 2 Homo sapiens 92-111 31570513-4 2019 We discovered that HELZ associates with various mRNA decay factors, including components of the carbon catabolite repressor 4-negative on TATA box (CCR4-NOT) deadenylase complex in human and Drosophila melanogaster cells. Carbon 96-102 C-C motif chemokine receptor 4 Homo sapiens 148-152 28186407-6 2017 This direct identification of a Ni-carbon bond in the catalytically competent CO-bound form of the A cluster of ACS provides definitive experimental structural evidence supporting the proposed organometallic mechanism of anaerobic acetyl-CoA synthesis. Carbon 35-41 acyl-CoA synthetase short chain family member 2 Homo sapiens 112-115 31579578-3 2019 CARB-CAR forest carbon offsets, based on forest mensuration and model simulation, are compared to a global database of directly measured forest carbon sequestration, or net ecosystem exchange (NEE) of forest CO2. Carbon 16-22 syntaxin 8 Homo sapiens 0-4 27974253-0 2017 V-shaped pits in HVPE-grown GaN associated with columnar inversion domains originating from foreign particles of alpha-Si3N4 and graphitic carbon. Carbon 139-145 gigaxonin Homo sapiens 28-31 31579578-9 2019 Exclusion of CO2 efflux via soil and ecosystem respiration precludes a valid net carbon accounting result for CARB-CAR and related protocols, consistent with our findings. Carbon 81-87 syntaxin 8 Homo sapiens 110-114 28167750-5 2017 Instead, we found that in HCMV-infected cells glucose carbon can be used for lipid synthesis by both ACLY and ACSS2 reactions. Carbon 54-60 acyl-CoA synthetase short chain family member 2 Homo sapiens 110-115 31579578-11 2019 We suggest that CARB-CAR and related protocols include NEE methodology for commercial forest carbon offsets to standardize methods, ensure in situ molecular specificity, verify claims of carbon emission reduction and harmonize carbon protocols for voluntary and compliance markets worldwide. Carbon 93-99 syntaxin 8 Homo sapiens 16-20 31579578-11 2019 We suggest that CARB-CAR and related protocols include NEE methodology for commercial forest carbon offsets to standardize methods, ensure in situ molecular specificity, verify claims of carbon emission reduction and harmonize carbon protocols for voluntary and compliance markets worldwide. Carbon 187-193 syntaxin 8 Homo sapiens 16-20 31579578-11 2019 We suggest that CARB-CAR and related protocols include NEE methodology for commercial forest carbon offsets to standardize methods, ensure in situ molecular specificity, verify claims of carbon emission reduction and harmonize carbon protocols for voluntary and compliance markets worldwide. Carbon 187-193 syntaxin 8 Homo sapiens 16-20 28006096-3 2017 By wrapping the fibers with a <100 nm thick graphitic carbon layer prior to RuO2 deposition (RuO2@C@SiO2), we retain the high mass activity of the RuO2 (40-60 mA mg-1 @ eta = 330 mV) and preserve the desirable macroscale properties of the 3D scaffold: porous, lightweight, flexible, and inexpensive. Carbon 57-63 endothelin receptor type A Homo sapiens 114-117 31616290-2 2019 To explain why certain 2-aminobenzothiazole/oxazole-type KCa activators (SKAs) are KCa3.1 selective we previously generated homology models of the C-terminal calmodulin-binding domain (CaM-BD) of KCa3.1 and KCa2.3 in complex with CaM using Rosetta modeling software. Carbon 58-59 potassium calcium-activated channel subfamily N member 4 Homo sapiens 83-89 27021430-3 2017 The NCs modified glassy carbon (GCE), NCs/GCE, electrodes showed a higher sensitivity (0.281muA/ppb) and lower LOD (0.12ppb) under optimized experimental conditions. Carbon 24-30 glycine decarboxylase Homo sapiens 32-35 27021430-3 2017 The NCs modified glassy carbon (GCE), NCs/GCE, electrodes showed a higher sensitivity (0.281muA/ppb) and lower LOD (0.12ppb) under optimized experimental conditions. Carbon 24-30 glycine decarboxylase Homo sapiens 42-45 31541188-4 2019 Each hPAH monomer comprises an N-terminal regulatory, a central catalytic and a C-terminal oligomerisation domain. Carbon 80-81 phenylalanine hydroxylase Homo sapiens 5-9 27297361-7 2017 Results of GC-TOFMS suggested that inhibition of mTORC1 reduce one-carbon amino acids, serine and glycine, in osteosarcoma cells. Carbon 67-73 CREB regulated transcription coactivator 1 Mus musculus 49-55 31482914-0 2019 Au-Luminol-decorated porous carbon nanospheres for the electrochemiluminescence biosensing of MUC1. Carbon 28-34 mucin 1, cell surface associated Homo sapiens 94-98 27834209-6 2017 They also revealed intercellular concentration gradients of aspartate, alanine, and phosphenolpyruvate to drive a second phosphoenolpyruvate carboxykinase (PEPCK)-type shuttle, which carries 10-14% of the carbon into the bundle sheath. Carbon 205-211 phosphoenolpyruvate carboxykinase (ATP) Zea mays 121-154 27834209-6 2017 They also revealed intercellular concentration gradients of aspartate, alanine, and phosphenolpyruvate to drive a second phosphoenolpyruvate carboxykinase (PEPCK)-type shuttle, which carries 10-14% of the carbon into the bundle sheath. Carbon 205-211 phosphoenolpyruvate carboxykinase (ATP) Zea mays 156-161 31505751-0 2019 Conjugation of Carbon Dots with beta-Galactosidase Enzyme: Surface Chemistry and Use in Biosensing. Carbon 15-21 galactosidase beta 1 Homo sapiens 32-50 27714489-9 2017 Carbon catabolite repressor (CCR)4 and CCR4-associated factor (CAF)1 in the CCR4-NOT complex function in mRNA poly(A) tail shortening. Carbon 0-6 CCR4-NOT core exoribonuclease subunit CCR4 Saccharomyces cerevisiae S288C 76-80 27824191-1 2016 Three-dimensional, hollow-structured carbon sphere nanocomposites (N,S-hcs) doped with nitrogen and sulfur were prepared using a soft template approach followed by a high-temperature treatment. Carbon 37-43 holocarboxylase synthetase Homo sapiens 71-74 31484382-1 2019 WS2-C is produced from a hydrothermal reaction, in which WS2 nano-sheets are coated with carbon, using glucose as the carbon source. Carbon 89-95 WS2C Homo sapiens 0-5 27775118-1 2016 We performed comprehensive studies on the photoluminescence properties of the carbon dots prepared from citric acid (C-dotsCA) and citric acid + ethylenediamine (C-dotsCA+EDA). Carbon 78-84 ectodysplasin A Homo sapiens 171-174 31484382-1 2019 WS2-C is produced from a hydrothermal reaction, in which WS2 nano-sheets are coated with carbon, using glucose as the carbon source. Carbon 118-124 WS2C Homo sapiens 0-5 31195173-1 2019 Polycyclic aromatic hydrocarbons containing at least 24 carbon atoms (>=C24-PAH) are often associated with pyrogenic processes such as combustion of fuel, wood or coal, and occur in the environment in diesel particulate matter, black carbon and coal tar. Carbon 25-31 phenylalanine hydroxylase Homo sapiens 79-82 33440533-2 2016 In this work, modified amorphous carbon films incorporating nitroxide groups (alpha-CNO) have been obtained by searching for a condensed analogue to classical soft antifouling materials. Carbon 33-39 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 84-87 31195173-1 2019 Polycyclic aromatic hydrocarbons containing at least 24 carbon atoms (>=C24-PAH) are often associated with pyrogenic processes such as combustion of fuel, wood or coal, and occur in the environment in diesel particulate matter, black carbon and coal tar. Carbon 56-62 phenylalanine hydroxylase Homo sapiens 79-82 31147049-1 2019 A novel electrochemical sensor based on the reduced graphene oxide-Cu/CuO-Ag nanocomposite modified glassy carbon electrode (rGO/Cu/CuO-Ag/GCE) has been applied for the simultaneous analysis of carbaryl and fenamiphos as two important pesticides. Carbon 107-113 glycine cleavage system protein H Homo sapiens 132-142 27799770-0 2016 Graphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway. Carbon 23-29 mitogen activated protein kinase 14 Rattus norvegicus 124-127 30974647-2 2016 The anodic copolymer P(BCz-co-ProDOT) with BCz/ProDOT-Me2 = 1/1 feed molar ratio showed high optical contrast (DeltaT%) and coloring efficiency (eta), measured as 52.5% and 153.5 cm2 C-1 at 748 nm, respectively. Carbon 24-25 endothelin receptor type A Homo sapiens 145-148 31352778-5 2019 We find that the presence of a carbon-rich PRB has a modest effect on the underlying soil microbial community structure in these experiments, indicating that existing consortia have the capability to carry out denitrification given favorable conditions. Carbon 31-37 RB transcriptional corepressor 1 Homo sapiens 43-46 27761435-8 2016 Further increases in free fatty acid production of 33% were obtained by knocking out the cytoplasmic glycerol-3-phosphate dehydrogenase, which flux analysis had shown was competing for carbon flux upstream with the carbon flux through the acetyl-CoA production pathway in the cytoplasm. Carbon 185-191 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 101-135 27761435-8 2016 Further increases in free fatty acid production of 33% were obtained by knocking out the cytoplasmic glycerol-3-phosphate dehydrogenase, which flux analysis had shown was competing for carbon flux upstream with the carbon flux through the acetyl-CoA production pathway in the cytoplasm. Carbon 215-221 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 101-135 31199008-2 2019 X-ray diffraction analysis shows that the complex has a very short Sc-C bond (2.138(2) A), and DFT calculations indicate that this unusual short bond length is due to the significant contribution of ionic coulomb interaction between carbon and scandium and the eta2 -O,C coordination fashion. Carbon 233-239 DNA polymerase iota Homo sapiens 261-265 27681606-3 2016 Here we demonstrate that sphingolipids with alpha-hydroxylated acyl-chains of at least 24 carbon atoms are enriched in secretory vesicle subdomains of the TGN and are critical for de novo polar secretory sorting of the auxin carrier PIN2 to apical membrane of Arabidopsis root epithelial cells. Carbon 90-96 Auxin efflux carrier family protein Arabidopsis thaliana 233-237 27659937-0 2016 PARP-1 depletion in combination with carbon ion exposure significantly reduces MMPs activity and overall increases TIMPs expression in cultured HeLa cells. Carbon 37-43 matrix metallopeptidase 2 Homo sapiens 79-83 27659937-12 2016 The expression of MMP-2 and MMP-9 in H-vector and HsiI showed different pattern after carbon ion exposure. Carbon 86-92 matrix metallopeptidase 2 Homo sapiens 18-23 27659937-16 2016 CONCLUSIONS: Our study demonstrates for the first time that PARP-1 inhibition in combination with carbon ion synergistically decreases MMPs activity along with overall increase of TIMPs. Carbon 98-104 matrix metallopeptidase 2 Homo sapiens 135-139 31388018-5 2019 The structure of SETD3 with Lys73-containing peptide reveals a bent conformation of Lys73, with its side chain aliphatic carbons tracing along the edge of imidazole ring and the terminal epsilon-amino group occupying a position nearly identical to the N3 atom of unmethylated histidine. Carbon 121-128 SET domain containing 3, actin histidine methyltransferase Homo sapiens 17-22 27381428-10 2016 A unique multidecker sandwich complex [(mu-eta(8):eta(8)-COT){Nd(c-C3H5-C[triple bond, length as m-dash]C-C(NCy)2)(mu-Cl)}2]4 (15) was prepared by reaction of anhydrous NdCl3 with K2COT and 1b in a one-pot reaction. Carbon 16-17 endothelin receptor type A Homo sapiens 43-46 27381428-10 2016 A unique multidecker sandwich complex [(mu-eta(8):eta(8)-COT){Nd(c-C3H5-C[triple bond, length as m-dash]C-C(NCy)2)(mu-Cl)}2]4 (15) was prepared by reaction of anhydrous NdCl3 with K2COT and 1b in a one-pot reaction. Carbon 16-17 endothelin receptor type A Homo sapiens 50-53 31041569-5 2019 We used poly(I:C)-treated nasal mucosal epithelial cells (HNECs) to find that the expression of KDM2B and Brg1 was also decreased, and the main expression position transferred from the nucleus to the nuclear membrane. Carbon 15-16 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Homo sapiens 106-110 27622474-8 2016 Transcriptomic and RT-qPCR analyses revealed that several genes were differentially expressed between X. dendrorhous mig1- and the wild-type strain when cultured with glucose as the sole carbon source. Carbon 187-193 transcription factor MIG1 Saccharomyces cerevisiae S288C 117-121 31366012-0 2019 Magnetized Carbon Nanotube Based Lateral Flow Immunoassay for Visual Detection of Complement Factor B. Carbon 11-17 complement factor B Homo sapiens 82-101 27289053-0 2016 Pyrolysis polygeneration of pine nut shell: Quality of pyrolysis products and study on the preparation of activated carbon from biochar. Carbon 116-122 NUT midline carcinoma family member 1 Homo sapiens 33-36 31366012-1 2019 The authors describe a magnetized carbon nanotube (MCNT) based lateral flow immunoassay (LFI) for visual detection of complement factor B (CFB) in blood. Carbon 34-40 complement factor B Homo sapiens 118-137 27187189-0 2016 Crossing the blood-brain-barrier with transferrin conjugated carbon dots: A zebrafish model study. Carbon 61-67 transferrin-a Danio rerio 38-49 31366012-1 2019 The authors describe a magnetized carbon nanotube (MCNT) based lateral flow immunoassay (LFI) for visual detection of complement factor B (CFB) in blood. Carbon 34-40 complement factor B Homo sapiens 139-142 27187189-2 2016 Here we use a zebrafish model to explore the possibility of using transferrin-conjugated carbon dots (C-Dots) to ferry compounds across the BBB. Carbon 89-95 transferrin-a Danio rerio 66-77 27187189-2 2016 Here we use a zebrafish model to explore the possibility of using transferrin-conjugated carbon dots (C-Dots) to ferry compounds across the BBB. Carbon 102-103 transferrin-a Danio rerio 66-77 31366070-1 2019 In this work, a series of carbon nanotubes (CNT)/Ag2S hybrid nanocomposites were successfully prepared by a facile precipitation method. Carbon 26-32 angiotensin II receptor type 1 Homo sapiens 49-53 31245986-0 2019 MOF-Derived Isolated Fe Atoms Implanted in N-Doped 3D Hierarchical Carbon as an Efficient ORR Electrocatalyst in Both Alkaline and Acidic Media. Carbon 67-73 lysine acetyltransferase 8 Homo sapiens 0-3 27323774-1 2016 RATIONALE: Compound 21 (C-21) is a highly selective nonpeptide angiotensin AT2 receptor (AT2R) agonist. Carbon 11-12 angiotensin II receptor type 2 Homo sapiens 75-78 31026642-5 2019 Moreover, the MDC with a CNT-CS sponge anode generated a high power density of 1776.6mW/m2 (per electrode area) and desalination rate of 16.5mgh-1, which are significantly higher than those of commercial carbon felt electrodes under the same conditions. Carbon 204-210 C-C motif chemokine ligand 22 Homo sapiens 14-17 26973057-5 2016 Detection of 2-HBP, a marker metabolite of 4S (sulfoxide-sulfone-sulfinate-sulfate) pathway, suggested that the newly isolated strains harbored metabolic activity for DBT desulfurization through the cleavage of C-S bond. Carbon 211-212 heme binding protein 1 Homo sapiens 15-18 31188590-1 2019 Herein, we report a novel carbothermal welding strategy to prepare atomically dispersed Pd sites anchored on a three-dimensional (3D) ZrO2 nanonet (Pd1@ZrO2) via two-step pyrolysis, which were evolved from isolated Pd sites anchored on linker-derived nitrogen-doped carbon (Pd1@NC/ZrO2). Carbon 266-272 programmed cell death 1 Homo sapiens 148-151 27278961-4 2016 The exception was C-7, a hydroxylated metabolite, largely formed by CYP2B6 and CYP3A4/5. Carbon 18-19 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 68-74 27132197-3 2016 This study quantified the net in-stream retention/release efficiencies (eta) of dissolved organic carbon (DOC) and its humic and protein-like fluorescent fractions along a Mediterranean river during drought, baseflow and flood conditions. Carbon 98-104 endothelin receptor type A Homo sapiens 72-75 31188590-5 2019 Moreover, the reductive carbon will result in abundant oxygen (O*) defects, which could help to capture the migratory Pd1 species, leaving a sintering-resistant Pd1@ZrO2 catalyst via atom trapping. Carbon 24-30 programmed cell death 1 Homo sapiens 118-121 31188590-5 2019 Moreover, the reductive carbon will result in abundant oxygen (O*) defects, which could help to capture the migratory Pd1 species, leaving a sintering-resistant Pd1@ZrO2 catalyst via atom trapping. Carbon 24-30 programmed cell death 1 Homo sapiens 161-164 31244161-1 2019 6,6",13,13"-Tetrahydro-6,6"-bipentacene (HBP), the intermediate molecule connecting pentacene to previously observed peripentacene and extended pentacene oligomers through the formation of a carbon-carbon bond, is synthesized and crystallographically characterized. Carbon 191-197 heme binding protein 1 Homo sapiens 41-44 27471193-5 2016 The bimetallic-MOF-derived nanoporous carbon are systematically characterized, highlighting the importance of precisely controlling the properties of the carbon materials. Carbon 38-44 lysine acetyltransferase 8 Homo sapiens 15-18 27471193-5 2016 The bimetallic-MOF-derived nanoporous carbon are systematically characterized, highlighting the importance of precisely controlling the properties of the carbon materials. Carbon 154-160 lysine acetyltransferase 8 Homo sapiens 15-18 27471193-6 2016 This can be done by finely tuning the components in the bimetallic MOF precursors, and thus designing optimal carbon materials for specific applications. Carbon 110-116 lysine acetyltransferase 8 Homo sapiens 67-70 31244161-1 2019 6,6",13,13"-Tetrahydro-6,6"-bipentacene (HBP), the intermediate molecule connecting pentacene to previously observed peripentacene and extended pentacene oligomers through the formation of a carbon-carbon bond, is synthesized and crystallographically characterized. Carbon 198-204 heme binding protein 1 Homo sapiens 41-44 31071695-0 2019 Development of a YAP(Ce) camera for the imaging of secondary electron bremsstrahlung x-ray emitted during carbon-ion irradiation toward the use of clinical conditions. Carbon 106-112 Yes1 associated transcriptional regulator Homo sapiens 17-20 27434767-0 2016 Corrigendum: A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Carbon 80-86 phosphoglycerate dehydrogenase Homo sapiens 15-20 31071695-11 2019 We confirmed that our developed YAP(Ce) camera is promising for imaging SEB x-rays during irradiation of carbon-ions even near clinical conditions. Carbon 105-111 Yes1 associated transcriptional regulator Homo sapiens 32-35 31140732-7 2019 More importantly, the Co/Cox My +Pt/C achieves higher voltaic efficiency and several times longer cycle life than conventional RuO2 +Pt/C catalysts in rechargeable Zn-air batteries. Carbon 22-23 cytochrome c oxidase subunit 8A Homo sapiens 25-28 27140531-2 2016 We focus on the first stage of peptide bond cleavage by matrix metalloproteinase-2 (MMP-2), that is, the nucleophilic attack of the zinc-coordinating water molecule on the carbonyl carbon atom of the scissile fragment of the substrate. Carbon 172-178 matrix metallopeptidase 2 Homo sapiens 56-82 27140531-2 2016 We focus on the first stage of peptide bond cleavage by matrix metalloproteinase-2 (MMP-2), that is, the nucleophilic attack of the zinc-coordinating water molecule on the carbonyl carbon atom of the scissile fragment of the substrate. Carbon 172-178 matrix metallopeptidase 2 Homo sapiens 84-89 31217464-3 2019 Here, we present the first in situ carbon and oxygen isotope data of texturally distinct calcite in calc-silicate xenoliths from arc volcanics in a case study from Merapi volcano (Indonesia). Carbon 35-41 mitochondrial calcium uptake 1 Homo sapiens 89-93 27269411-4 2016 In this study, nitrogen-doped carbon nanotube membranes and Pt carbon cloths were utilized as filtration material and cathode to fabricate a modularized filtration air cathode MDC (F-MDC). Carbon 30-36 C-C motif chemokine ligand 22 Homo sapiens 176-179 27269411-4 2016 In this study, nitrogen-doped carbon nanotube membranes and Pt carbon cloths were utilized as filtration material and cathode to fabricate a modularized filtration air cathode MDC (F-MDC). Carbon 30-36 C-C motif chemokine ligand 22 Homo sapiens 181-186 27269411-4 2016 In this study, nitrogen-doped carbon nanotube membranes and Pt carbon cloths were utilized as filtration material and cathode to fabricate a modularized filtration air cathode MDC (F-MDC). Carbon 63-69 C-C motif chemokine ligand 22 Homo sapiens 176-179 27269411-4 2016 In this study, nitrogen-doped carbon nanotube membranes and Pt carbon cloths were utilized as filtration material and cathode to fabricate a modularized filtration air cathode MDC (F-MDC). Carbon 63-69 C-C motif chemokine ligand 22 Homo sapiens 181-186 30935948-7 2019 Consequently, utilization of glutamine carbon for biomass synthesis was profoundly affected, suggesting galectin-12 as a novel inhibitor of glutamine anaplerosis in colon cancer cells. Carbon 39-45 galectin 12 Homo sapiens 104-115 27058401-2 2016 Here we present pyrolytic carbon-coated stainless steel felt (C-SS felt) as a high-performance and scalable anode. Carbon 26-32 cytidine monophosphate N-acetylneuraminic acid synthetase Homo sapiens 62-66 31066398-3 2019 Treatment of 6a with non-conjugated small molecules such as phenyl isocyanates, phenyl isothiocyanate, and benzaldehyde resulted in formation of Sc/gamma-C [4 + 2] cycloaddition products 7-9 because of nucleophilic reactivity at the beta-diketiminato gamma-carbon, with retention of ScP interactions. Carbon 257-263 interleukin 2 receptor subunit gamma Homo sapiens 148-155 27129885-14 2016 C+P-IR or C/P-RIR were four to eight times more likely to exhibit low femoral neck CSMI or CSA when compared with C+P-R. Lumbar spine aBMD and Z-score were lower in C+P-IR when compared with C+P-R (p<=0.003). Carbon 0-1 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 91-94 31460120-0 2019 Zn-Catalyzed Multicomponent KA2 Coupling: One-Pot Assembly of Propargylamines Bearing Tetrasubstituted Carbon Centers. Carbon 103-109 glutamate ionotropic receptor kainate type subunit 5 Homo sapiens 28-31 27113132-2 2016 In Arabidopsis plant, the ubiquitin ligase ATL31 controls 14-3-3 stability via both direct interaction and ubiquitination, and this consequently regulates post-germinative growth in response to carbon and nitrogen nutrient availability. Carbon 194-200 carbon/nitrogen insensitive 1 Arabidopsis thaliana 43-48 26820360-1 2016 An ultrasensitive electrochemical nanostructured immunosensor for a breast cancer biomarker carbohydrate antigen 15-3 (CA 15-3) was fabricated using non-covalent functionalized graphene oxides (GO/Py-COOH) as sensor probe and multiwalled carbon nanotube (MWCNTs)-supported numerous ferritin as labels. Carbon 238-244 mucin 1, cell surface associated Homo sapiens 82-126 31183566-10 2019 Graphical abstract Dual amperometric immunosensing of the metastasis-related biomarkers IL-13Ralpha2 and CDH-17 in human colorectal cancer cells and tissues by using grafted screen-printed electrodes and composites of quantum dots and carbon nanotubes as nanocarriers. Carbon 235-241 interleukin 13 receptor subunit alpha 2 Homo sapiens 88-100 27106165-2 2016 Through direct surface modification with ammonium hexafluorophosphate (NH4 PF6 ), phosphorus can be successfully incorporated onto the surface of the carbon felt by forming phosphate functional groups with -OH chemical moieties that exhibit good hydrophilicity. Carbon 150-156 sperm associated antigen 17 Homo sapiens 75-78 27548479-8 2016 Given that propionate is exclusively derived from bacterial fermentation, these data provide evidence for an important role of mucin fermenting bacteria in the carbon flux of the lower airways. Carbon 160-166 LOC100508689 Homo sapiens 127-132 30808730-6 2019 Profiling of the metabolome demonstrates that suppression of CPS1 potentiates the effects of EGFR inhibition on central carbon metabolism, pyrimidine biosynthesis, and arginine metabolism, coinciding with reduced glycolysis and mitochondrial respiration. Carbon 120-126 carbamoyl-phosphate synthase 1 Homo sapiens 61-65 27203127-0 2016 Dosimetric comparisons of carbon ion treatment plans for 1D and 2D ripple filters with variable thicknesses. Carbon 26-32 leiomodin 1 Homo sapiens 57-66 27505731-5 2016 For ITO, thermally driven damage was related to free carrier absorption and, for GaN, carbon complexes were proposed as potential damage precursors or markers. Carbon 86-92 gigaxonin Homo sapiens 81-84 30915433-4 2019 However, the external NADH dehydrogenases (Nde1/2) and the L-glycerol 3-phosphate shuttle (composed of Gpd1/2 and Gut2), both coupled to the respiratory chain, are known to contribute to cytosolic NAD+ regeneration during growth on non-fermentable carbon sources. Carbon 248-254 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 114-118 27317643-2 2016 Through one-carbon elongation in the respective pharmacophoric regions, N-(3-fluoro-4-methylsulfonamidomethylphenyl)urea was identified as a novel and potent TRPV1 antagonistic template. Carbon 12-18 transient receptor potential cation channel subfamily V member 1 Homo sapiens 158-163 27436713-8 2016 (14)C labeling showed that amy3 bam1 plants have reduced carbon export to the root, affecting osmolyte accumulation and root growth during stress. Carbon 57-63 beta-amylase 1 Arabidopsis thaliana 32-36 27304078-4 2016 In this respect, a simple carbazole-based HTM X25 was designed on the basis of a reference HTM, triphenylamine-based X2, by simply linking two neighboring phenyl groups in a triphenylamine unit through a carbon-carbon single bond. Carbon 204-210 frataxin Homo sapiens 46-49 27304078-4 2016 In this respect, a simple carbazole-based HTM X25 was designed on the basis of a reference HTM, triphenylamine-based X2, by simply linking two neighboring phenyl groups in a triphenylamine unit through a carbon-carbon single bond. Carbon 211-217 frataxin Homo sapiens 46-49 27107972-8 2016 ELOVL5 and ELOVL6 mRNA levels were suggestive of overexpression of membrane phospholipids containing elongated fatty acids with 16, 18, and 20 carbons. Carbon 143-150 ELOVL fatty acid elongase 5 Bos taurus 0-6 29964467-1 2016 Activated carbon supported cobalt catalysts (Co/AC) were prepared through wet impregnation and high temperature calcination methods. Carbon 10-16 phosphopantothenoylcysteine decarboxylase Homo sapiens 45-50 27362224-9 2016 We demonstrate carbon synthesis for large-pore zeolites (FAU, EMT and beta), a one-dimensional medium-pore zeolite (LTL), and even small-pore zeolites (MFI and LTA). Carbon 15-21 FAU ubiquitin like and ribosomal protein S30 fusion Homo sapiens 57-60 27107386-1 2016 The effect that the textural properties of rayon-based activated carbon fibers (ACFs), such as the BET surface area and pore size distribution (PSD), have on the adsorption of differently sized molecules, namely, brilliant yellow (BY), methyl orange (MO) and phenol (PH), was investigated in the aqueous phase. Carbon 65-71 delta/notch like EGF repeat containing Homo sapiens 99-102 26975754-5 2016 Based on these results, we engineered a BY4741 strain that overexpressed ARO10 and contained an aro8Delta deletion, and demonstrated that the strain produced 96 mg/L 2-PE from glucose as the sole carbon source. Carbon 196-202 phenylpyruvate decarboxylase ARO10 Saccharomyces cerevisiae S288C 73-78 27043198-7 2016 Our results illustrate the potential of small-diameter carbon nanotube porins as a proton conductor material and suggest that strong spatial confinement is a key factor in enabling efficient proton transport. Carbon 55-61 thymus, brain and testes associated Homo sapiens 133-140 27033608-2 2016 The scaling of recombinant-chymosin production was carried out by a fed-batch strategy in a stirred-tank bioreactor using biodiesel-byproduct crude glycerol as the carbon source and pure methanol for the induction of chymosin expression, achieving a biomass concentration of 158 g DCW/L and a maximum coagulant activity of 192 IMCU/ml after 120 h of methanol induction. Carbon 164-170 chymosin Bos taurus 27-35 27350173-5 2016 Skeletal muscle mRNA expression of serine/one-carbon/glycine biosynthesis pathway genes (Phgdh, Psat1 and Psph) and the gluconeogenic enzyme, phosphoenolpyruvate carboxykinase-M (Pck2/PEPCK-M), increased during treatment with BA, and to a lesser extent GH (p < 0.001, treatment x time interaction). Carbon 46-52 phosphoglycerate dehydrogenase Sus scrofa 89-94 27350173-5 2016 Skeletal muscle mRNA expression of serine/one-carbon/glycine biosynthesis pathway genes (Phgdh, Psat1 and Psph) and the gluconeogenic enzyme, phosphoenolpyruvate carboxykinase-M (Pck2/PEPCK-M), increased during treatment with BA, and to a lesser extent GH (p < 0.001, treatment x time interaction). Carbon 46-52 phosphoserine aminotransferase 1 Sus scrofa 96-101 27325086-0 2016 Carbon materials: MOF morphologies in control. Carbon 0-6 lysine acetyltransferase 8 Homo sapiens 18-21 26947057-4 2016 Saccharomyces cerevisiae lacking VDAC1 (Deltapor1) is a very convenient model system, since it shows an impaired growth rate on non-fermentable carbon source. Carbon 144-150 voltage dependent anion channel 1 Homo sapiens 33-38 27016649-5 2016 This contrasts with results for Flaveria CA mutants, and has opened discussion on the role of CA in the C4 carbon concentrating mechanism. Carbon 107-113 carbonic anhydrase Zea mays 94-96 27265379-2 2016 The efficacy of the apurinic-apyrimidinic endonuclease 1 (APE1) in the cleavage of abasic site lesions in the presence of carboxylated multi-walled carbon nanotubes (MWCNT-COOH) and graphene oxide (GO) are compared. Carbon 148-154 apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens 20-56 27265379-2 2016 The efficacy of the apurinic-apyrimidinic endonuclease 1 (APE1) in the cleavage of abasic site lesions in the presence of carboxylated multi-walled carbon nanotubes (MWCNT-COOH) and graphene oxide (GO) are compared. Carbon 148-154 apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens 58-62 27109872-6 2016 Our results show that it is possible to improve stability and optimum coverage of alkyl functionalized SAMs linked through a direct Si-C bond by incorporating alkyl chains linked to Si through a different linker group, while preserving the interface electronic structure that determines key electronic properties. Carbon 135-136 methionine adenosyltransferase 1A Homo sapiens 103-107 27212712-4 2016 We recorded by action spectroscopy the relative intensities of photo-fragmentation and photo-ionization for a set of eight PAH cations ranging in size from 14 to 24 carbon atoms, with different structures. Carbon 165-171 phenylalanine hydroxylase Homo sapiens 123-126 26952415-1 2016 A sensitive electrochemical sensor based on bovine serum albumin (BSA)/poly (diallyldimethylammonium chloride) (PDDA) functionalized graphene nanosheets (PDDA-G) composite film modified glassy carbon electrode (BSA/PDDA-G/GCE) had been developed to investigate the oxidative protein damage and protections of protein from damage by flavonoids. Carbon 193-199 glycine cleavage system protein H Homo sapiens 215-225 27030290-4 2016 Among them, the carbon-1 : 2 sample shows a high BET surface area of up to 818.5 m(2) g(-1) and a large total pore volume of 1.78 cm(3) g(-1) as well as a specific capacitance of 107.0 F g(-1) at 1 A g(-1). Carbon 16-22 delta/notch like EGF repeat containing Homo sapiens 49-52 26971507-0 2016 Theoretical prediction of complexes with a sulfur-carbon triple bond: SCX(2+), SCXF(+), and SCXF2 (X = Be, Mg, Ca). Carbon 50-56 scleraxis bHLH transcription factor Homo sapiens 70-73 26971507-1 2016 A new series of compounds with a sulfur-carbon triple bond-SCX(2+), SCXF(+), and SCXF2 (X = Be, Mg, Ca)-were investigated using quantum chemical computations. Carbon 40-46 scleraxis bHLH transcription factor Homo sapiens 59-62 26971507-7 2016 In general, all of the results calculated in this work clearly indicate that the SCX(2+), SCXF(+), and SCXF2 (X = Be, Mg, Ca) species each contain a strong sulfur-carbon triple bond. Carbon 163-169 scleraxis bHLH transcription factor Homo sapiens 81-84 26935338-6 2016 Furthermore, the combination treatment of Muc1 with poly I:C increased anti-Muc1 IgM and anti-Muc1 IgG titers, and altered the balance of IgG2a and IgG1, all of which increased the T helper (Th)1 polarized immune response. Carbon 59-60 mucin 1, cell surface associated Homo sapiens 42-46 26935338-6 2016 Furthermore, the combination treatment of Muc1 with poly I:C increased anti-Muc1 IgM and anti-Muc1 IgG titers, and altered the balance of IgG2a and IgG1, all of which increased the T helper (Th)1 polarized immune response. Carbon 59-60 mucin 1, cell surface associated Homo sapiens 76-80 26935338-6 2016 Furthermore, the combination treatment of Muc1 with poly I:C increased anti-Muc1 IgM and anti-Muc1 IgG titers, and altered the balance of IgG2a and IgG1, all of which increased the T helper (Th)1 polarized immune response. Carbon 59-60 mucin 1, cell surface associated Homo sapiens 76-80 26979124-3 2016 MATERIALS & METHODS: Functionalized (PEG or IgG) carbon-encapsulated platinum-spiked iron carbide nanoparticles were injected intravenously in mice (single or repeated dose administration). Carbon 53-59 immunoglobulin heavy chain (V7183 family) Mus musculus 41-51 26801584-0 2016 MMP-9-Dependent Serum-Borne Bioactivity Caused by Multiwalled Carbon Nanotube Exposure Induces Vascular Dysfunction via the CD36 Scavenger Receptor. Carbon 62-68 matrix metallopeptidase 9 Mus musculus 0-5 27026438-0 2016 Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation. Carbon 13-19 high mobility group box 1 Homo sapiens 93-98 27337906-6 2016 (3) The SOC density increments to reach the real level of carbon sequestration potential estimated by classification grading method, saturation method and weighting method were 6.76 t hm-2, 5.21 t hm-2, 4.56 t hm-2 respectively. Carbon 58-64 cholinergic receptor muscarinic 2 Homo sapiens 186-190 27337906-6 2016 (3) The SOC density increments to reach the real level of carbon sequestration potential estimated by classification grading method, saturation method and weighting method were 6.76 t hm-2, 5.21 t hm-2, 4.56 t hm-2 respectively. Carbon 58-64 cholinergic receptor muscarinic 2 Homo sapiens 201-205 27337906-6 2016 (3) The SOC density increments to reach the real level of carbon sequestration potential estimated by classification grading method, saturation method and weighting method were 6.76 t hm-2, 5.21 t hm-2, 4.56 t hm-2 respectively. Carbon 58-64 cholinergic receptor muscarinic 2 Homo sapiens 201-205 26856444-6 2016 The highest NO removal efficiency for the waste tyre derived activated carbons was ~75% which was obtained with the adsorbent treated with KOH which correlated with both the highest BET surface area and largest micropore volume. Carbon 71-78 delta/notch like EGF repeat containing Homo sapiens 182-185 26903234-0 2016 H18 Carbon: A New Metallic Phase with sp2-sp3 Hybridized Bonding Network. Carbon 4-10 H1.8 linker histone Homo sapiens 0-3 26903234-2 2016 Here, based on first-principles calculations, we discover a novel stable metallic carbon allotrope (termed H18 carbon) in () symmetry with a mixed sp(2)-sp(3) hybridized bonding network. Carbon 82-88 H1.8 linker histone Homo sapiens 107-110 26903234-2 2016 Here, based on first-principles calculations, we discover a novel stable metallic carbon allotrope (termed H18 carbon) in () symmetry with a mixed sp(2)-sp(3) hybridized bonding network. Carbon 111-117 H1.8 linker histone Homo sapiens 107-110 26903234-3 2016 The dynamical stability of H18 carbon is verified by phonon mode analysis and molecular dynamics simulations, and its mechanical stability is analyzed by elastic constants, bulk modulus, and shear modulus. Carbon 31-37 H1.8 linker histone Homo sapiens 27-30 26903234-4 2016 By simulating the x-ray diffraction patterns, we propose that H18 carbon would be one of the unidentified carbon phases observed in recent detonation experiments. Carbon 66-72 H1.8 linker histone Homo sapiens 62-65 27168493-5 2016 By combining extra- and intracellular steady state metabolite measurements by liquid chromatography-mass spectrometry with metabolic flux assays using labeled glucose and functional assays, we demonstrate that knockdown of ATG7 results in decreased glycolysis and increased flux of labeled carbons through the mitochondrial tricarboxylic acid cycle. Carbon 290-297 autophagy related 7 Homo sapiens 223-227 27184763-3 2016 Both novel and known locus-specific DNA-protein interactions were identified at the ENO2 and GAL1 promoter regions of Saccharomyces cerevisiae, and revealed subgroups of proteins present in significantly different levels at the loci in cells grown on glucose versus galactose as the carbon source. Carbon 283-289 galactokinase Saccharomyces cerevisiae S288C 93-97 27258319-9 2016 (ii) During the post-hypoxia recovery period, the alanine aminotransferase/glutamate dehydrogenase cycle mobilizes this carbon from alanine store. Carbon 120-126 glutamic--pyruvic transaminase Homo sapiens 50-74 27049646-0 2016 Preparation of High-Efficiency Cytochrome c-Imprinted Polymer on the Surface of Magnetic Carbon Nanotubes by Epitope Approach via Metal Chelation and Six-Membered Ring. Carbon 89-95 LOC104968582 Bos taurus 31-43 27049646-1 2016 A novel epitope molecularly imprinted polymer on the surface of magnetic carbon nanotubes (MCNTs@EMIP) was successfully fabricated to specifically recognize target protein cytochrome c (Cyt C) with high performance. Carbon 73-79 LOC104968582 Bos taurus 172-184 27049646-1 2016 A novel epitope molecularly imprinted polymer on the surface of magnetic carbon nanotubes (MCNTs@EMIP) was successfully fabricated to specifically recognize target protein cytochrome c (Cyt C) with high performance. Carbon 73-79 LOC104968582 Bos taurus 186-191 26952744-0 2016 [RuCl2(eta6-p-cymene)] complexes bearing phosphinous acid ligands: preparation, application in C-H bond functionalization and mechanistic investigations. Carbon 3-4 endothelin receptor type A Homo sapiens 7-10 26991842-1 2016 We quantum chemically explore the thermodynamics and kinetics of all 65 possible mechanistic pathways of the Bingel-Hirsch addition of dimethyl bromomalonate to the endohedral metallofullerene La@C2v -C82 that result from the combination of 24 nonequivalent carbon atoms and 35 different bonds present in La@C2v -C82 by using dispersion-corrected DFT calculations. Carbon 258-264 complement C8 beta chain Homo sapiens 201-204 26119934-5 2016 Amplex glucose assay, fluorescence and carbon-13 tracing studies demonstrate that FAK promotes glucose consumption and glucose-to-lactate conversion. Carbon 39-45 protein tyrosine kinase 2 Homo sapiens 82-85 26762934-5 2016 Denitrifier gene copy concentrations per gram of soil (GCC) varied in response to carbon type amendment (P < 0.01). Carbon 82-88 guanylate cyclase 2C Homo sapiens 55-58 26516686-0 2016 Nitrated carbon nanoblisters for high-performance glucose dehydrogenase bioanodes. Carbon 9-15 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 50-71 26516686-3 2016 Here we present the fabrication of flexible carbon fibers modified with nitrated carbon nanoblisters and their application as high-performance GDh bioanodes. Carbon 44-50 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 143-146 26516686-3 2016 Here we present the fabrication of flexible carbon fibers modified with nitrated carbon nanoblisters and their application as high-performance GDh bioanodes. Carbon 81-87 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 143-146 26556185-1 2016 In this paper, a double signal electrochemical Human immunoglobulin G (HIgG) immunosensor based on AgNPs/carbon nanocomposite (Ag/C NC) as the signal probe and catalytic substrate was developed for fast and sensitive detection of HIgG. Carbon 105-111 protein kinase cAMP-dependent type I regulatory subunit alpha Homo sapiens 130-134 26890684-2 2016 In this study, we found an efficient strategy to prepare nitrogen, phosphorus, and sulfur co-doped hollow carbon shells (denote as NPS-HCS) with a surface area of 1020 m(2) g(-1). Carbon 106-112 holocarboxylase synthetase Homo sapiens 135-138 26809004-0 2016 Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood-brain barrier in vitro and in vivo. Carbon 31-37 LDL receptor related protein 1 Rattus norvegicus 17-21 26773545-8 2016 Experimental manipulation of BnLEC1 caused transcriptional changes in enzymes participating in sucrose metabolism, glycolysis, and FA biosynthesis, suggesting an enhanced carbon flux towards FA biosynthesis in tissues over-expressing BnLEC1. Carbon 171-177 nuclear transcription factor Y subunit B-9-like Brassica napus 29-35 26773545-8 2016 Experimental manipulation of BnLEC1 caused transcriptional changes in enzymes participating in sucrose metabolism, glycolysis, and FA biosynthesis, suggesting an enhanced carbon flux towards FA biosynthesis in tissues over-expressing BnLEC1. Carbon 171-177 nuclear transcription factor Y subunit B-9-like Brassica napus 234-240 26903234-4 2016 By simulating the x-ray diffraction patterns, we propose that H18 carbon would be one of the unidentified carbon phases observed in recent detonation experiments. Carbon 106-112 H1.8 linker histone Homo sapiens 62-65 26904506-4 2016 Interestingly, using phosphorylated H2AX as a DSB marker, our data in human fibroblasts revealed that after therapy-relevant spread-out Bragg peak irradiation with carbon ions DSBs are very efficiently rejoined, despite an increased RBE for cell survival. Carbon 164-170 H2A.X variant histone Homo sapiens 36-40 26912861-5 2016 Thus, mTORC1 stimulates the mTHF cycle, which contributes one-carbon units to enhance production of purine nucleotides in response to growth signals. Carbon 62-68 CREB regulated transcription coactivator 1 Mus musculus 6-12 26824618-6 2016 Furthermore, nitrogen-doped carbon microspheres are prepared by the direct carbonization of these polymer microspheres, which exhibit microporous BET surface areas of 400-500 m(2) g(-1), high nitrogen contents of 5-6 wt %, and a good CO2 adsorption capacity up to 3.6 mmol g(-1) at 0 C. KOH activation is further employed to develop the porous texture of carbon microspheres without sacrificing the spherical morphology. Carbon 28-34 delta/notch like EGF repeat containing Homo sapiens 146-149 26824618-7 2016 The resultant activated carbon microspheres exhibit small particle size (<80 nm), high BET surface areas of 1500-2000 m(2) g(-1), and considerable nitrogen content of 2.2-2.0 wt %. Carbon 24-30 delta/notch like EGF repeat containing Homo sapiens 90-93 26542830-7 2016 The recycled activated carbon has a BET surface area of up to 1200m(2)/g and the recycled acetonitrile has a high purity. Carbon 23-29 delta/notch like EGF repeat containing Homo sapiens 36-39 26595179-1 2016 This study aimed to evaluate the influence of COD/N ratio and carbon source on simultaneous nitrogen and carbon removal processes. Carbon 105-111 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 46-49 26374540-2 2016 The adsorbent of N-doped ordered mesoporous carbon (M-OMC) with high BET surface area of 1901 m(2)/g, large pore volume of 1.64 cm(3)/g and uniform pore size of 3.45 nm has been successfully synthesized via evaporation-induced self-assembly (EISA) method. Carbon 44-50 delta/notch like EGF repeat containing Homo sapiens 69-72 26377965-2 2016 Ethylenediamine-functionalized magnetic carbon nanotubes (EDA@Mag-CNTs) were synthesised by a simple one-pot reaction and were used as sorbent in Mag-dSPE procedure. Carbon 40-46 ectodysplasin A Homo sapiens 58-61 28214879-10 2016 Our findings were associated with modified hepatic levels of the mRNAs of several carbon metabolism genes: a reduction of transcripts for liver glucokinase and fatty acid synthase and augmentation of those for carnitine palmitoyl transferase 1 and phosphoenolpyruvate carboxykinase as markers for glycolysis, fatty acid synthesis, beta-oxidation, and gluconeogenesis, respectively. Carbon 82-88 glucokinase Mus musculus 144-155 26584857-1 2015 A detailed study on all stages associated with the reaction mechanisms for the denitrogenation of 2,3-diazabicyclo[2.2.1]hept-2-ene derivatives (DBX, with X substituents at the methano-bridge carbon atom, X = H and OH) is presented. Carbon 192-198 DEAD-box helicase 3 X-linked Homo sapiens 145-148 26565522-3 2015 The synthesized CoxC/carbon nanotube features a high BET surface area, large pore volume and high graphitic content, which greatly favors enhanced ORR properties. Carbon 21-27 delta/notch like EGF repeat containing Homo sapiens 53-56 27551487-4 2015 Functioning as a molecular switch, AMPK promotes glycolysis by activating PFK2, and facilitates mitochondrial metabolism of non-glucose carbon sources thereby maintaining cellular ATP level. Carbon 136-142 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 35-39 26282451-3 2015 The thiophene/selenophene-fused acenes emit blue fluorescence with quantum yields of 0.39 for PyPT and 0.04 for PyPS in organic solvents, whereas the all-carbon molecule HBP emits green fluorescence. Carbon 154-160 heme binding protein 1 Homo sapiens 170-173 26378686-9 2015 The estimated increases in SBP and DBP were 4.9 mmHg [95% confidence interval (CI) 2.9-6.8] and 3.7 mmHg (95% CI 2.3-5.1) at high elemental carbon level (>=median), and were -1.3 mmHg (95% CI -6.3 to 3.6) and 0.7 mmHg (95% CI -2.8 to 4.2) at low elemental carbon level (<median) per 10 C decrease in daily minimum temperature. Carbon 140-146 selenium binding protein 1 Homo sapiens 27-30 26378686-9 2015 The estimated increases in SBP and DBP were 4.9 mmHg [95% confidence interval (CI) 2.9-6.8] and 3.7 mmHg (95% CI 2.3-5.1) at high elemental carbon level (>=median), and were -1.3 mmHg (95% CI -6.3 to 3.6) and 0.7 mmHg (95% CI -2.8 to 4.2) at low elemental carbon level (<median) per 10 C decrease in daily minimum temperature. Carbon 259-265 selenium binding protein 1 Homo sapiens 27-30 26440308-1 2015 Sequestration of CO2, either from gas mixtures or directly from air (direct air capture, DAC), could mitigate carbon emissions. Carbon 110-116 arylacetamide deacetylase Homo sapiens 89-92 26573531-7 2015 Knock-down of PHF11 resulted in increased interleukin-8 expression and secretion immediately following treatment with poly(I:C), as well as changes in the cellular distribution of membrane-bound and increased nuclear claudin-1 that was observed up to 3 days after the withdrawal of poly(I:C). Carbon 289-290 PHD finger protein 11 Homo sapiens 14-19 26134167-7 2015 Transcriptomic and metabolomic analyses indicate that the lack of GAPCp activity affects nitrogen and carbon metabolism as well as mineral nutrition and that glycerate and glutamine are the main metabolites responding to GAPCp activity. Carbon 102-108 glyceraldehyde-3-phosphate dehydrogenase C subunit 1 Arabidopsis thaliana 66-71 26494026-3 2015 Here we present an oxygenated amorphous carbon (a-COx) produced by physical vapour deposition that has several properties in common with graphite oxide. Carbon 40-46 cytochrome c oxidase subunit 8A Homo sapiens 50-53 26494026-7 2015 These results suggest that a-COx could play a key role in non-volatile memory technology and carbon-based electronics. Carbon 93-99 cytochrome c oxidase subunit 8A Homo sapiens 29-32 26332709-1 2015 High-temperature chlorination of fullerene C88 (isomer 33) with VCl4 gives rise to skeletal transformations affording several nonclassical (NC) fullerene chlorides, C86 (NC1)Cl24/26 and C84 (NC2)Cl26 , with one and two heptagons, respectively, in the carbon cages. Carbon 251-257 down-regulator of transcription 1 Homo sapiens 191-194 26804469-1 2016 Condensation of fac-Re(5,6-diamino-1,10-phenanthroline)(CO)3Cl to o-quinone edge defects on graphitic carbon surfaces generates graphite-conjugated rhenium (GCC-Re) catalysts that are highly active for CO2 reduction to CO in acetonitrile electrolyte. Carbon 102-108 guanylate cyclase 2C Homo sapiens 157-160 26804469-3 2016 GCC-Re species on glassy carbon surfaces display catalytic currents greater than 50 mA cm(-2) with 96 +- 3% Faradaic efficiency for CO production. Carbon 25-31 guanylate cyclase 2C Homo sapiens 0-3 26706770-6 2016 The concentrations of PAHs and BEQs of the AhR-mediated activity attributed to these chemicals in the exhaustive extracts can be back calculated from those in the PDMS extracts via a general organic carbon-PDMS partition coefficient. Carbon 199-205 aryl hydrocarbon receptor Homo sapiens 43-46 26231655-2 2015 Decomposition of carbon in the PRB drives groundwater anoxic, fostering microbial denitrification. Carbon 17-23 RB transcriptional corepressor 1 Homo sapiens 31-34 30690513-1 2019 Studies have indicated that the carbon starvation response leads to the reprogramming of the transcriptome and metabolome, and many genes, including several important regulators, such as the group S1 basic leucine zipper transcription factors (TFs) bZIP1, bZIP11 and bZIP53, the SNAC-A TF ATAF1, etc., are involved in these physiological processes. Carbon 32-38 basic leucine-zipper 1 Arabidopsis thaliana 249-254 26286937-6 2015 In media with beta-hydroxybutyrate (BHB) as carbon source, primary FRDA fibroblasts grow poorly and/or lose viability over several days. Carbon 44-50 frataxin Homo sapiens 67-71 26760052-4 2016 is based on CH5(+) and Olah"s related nonclassical carbonium ion chemistry. Carbon 51-60 oleoyl-ACP hydrolase Homo sapiens 23-27 30690513-1 2019 Studies have indicated that the carbon starvation response leads to the reprogramming of the transcriptome and metabolome, and many genes, including several important regulators, such as the group S1 basic leucine zipper transcription factors (TFs) bZIP1, bZIP11 and bZIP53, the SNAC-A TF ATAF1, etc., are involved in these physiological processes. Carbon 32-38 basic region/leucine zipper motif 53 Arabidopsis thaliana 267-273 26608667-3 2016 BAS1 encodes CYP734A1, which inactivates the biologically active BRs via C-26 hydroxylation and is down-regulated by a BR-responsive transcription factor, BZR1. Carbon 13-14 Cytochrome P450 superfamily protein Arabidopsis thaliana 0-4 30690513-3 2019 The overexpression of ANAC032 inhibits photosynthesis and induces reactive oxygen species accumulation in chloroplasts, thereby reducing sugar accumulation and resulting in carbon starvation. Carbon 173-179 NAC domain containing protein 32 Arabidopsis thaliana 22-29 25957495-10 2015 Our work identifies novel Ume6 repressed genes during growth and development and reveals a strong effect of the carbon source on the derepression pattern of transcripts in growing and developmentally arrested ume6/ume6 mutant cells. Carbon 112-118 DNA-binding transcriptional regulator UME6 Saccharomyces cerevisiae S288C 26-30 25957495-10 2015 Our work identifies novel Ume6 repressed genes during growth and development and reveals a strong effect of the carbon source on the derepression pattern of transcripts in growing and developmentally arrested ume6/ume6 mutant cells. Carbon 112-118 DNA-binding transcriptional regulator UME6 Saccharomyces cerevisiae S288C 209-213 30690513-4 2019 ANAC032 reprograms carbon and nitrogen metabolism by increasing sugar and amino acid catabolism in plants. Carbon 19-25 NAC domain containing protein 32 Arabidopsis thaliana 0-7 25957495-10 2015 Our work identifies novel Ume6 repressed genes during growth and development and reveals a strong effect of the carbon source on the derepression pattern of transcripts in growing and developmentally arrested ume6/ume6 mutant cells. Carbon 112-118 DNA-binding transcriptional regulator UME6 Saccharomyces cerevisiae S288C 214-218 30690513-6 2019 Taken together, these results show that ANAC032 is an important regulator of the carbon/energy status that represses photosynthesis to induce carbon starvation. Carbon 81-87 NAC domain containing protein 32 Arabidopsis thaliana 40-47 30690513-6 2019 Taken together, these results show that ANAC032 is an important regulator of the carbon/energy status that represses photosynthesis to induce carbon starvation. Carbon 142-148 NAC domain containing protein 32 Arabidopsis thaliana 40-47 30668809-6 2019 The frequency of DSB and SSB was computed for proton and carbon ions. Carbon 57-63 small RNA binding exonuclease protection factor La Homo sapiens 25-28 26483804-0 2015 The transporter GAT1 plays an important role in GABA-mediated carbon-nitrogen interactions in Arabidopsis. Carbon 62-68 Thioredoxin superfamily protein Arabidopsis thaliana 16-20 26671348-0 2016 Enhancing the carbon capture capacities of a rigid ultra-microporous MOF through gate-opening at low CO2 pressures assisted by swiveling oxalate pillars. Carbon 14-20 lysine acetyltransferase 8 Homo sapiens 69-72 26781725-7 2016 The mutant HXT7(F79S) shows improved xylose uptake rates (Vmax = 186.4 +- 20.1 nmol min(-1) mg(-1)) that allows the S. cerevisiae strain to show significant growth with xylose as the sole carbon source, as well as partial co-utilization of glucose and xylose in a mixed sugar cultivation. Carbon 188-194 hexose transporter HXT7 Saccharomyces cerevisiae S288C 11-15 30988268-3 2019 TGA coupled FTIR and XPS revealed that EG could disassembled before RPUF under heating treatment, and it could form a pyknotic and enahnced residual carbon layer on RPUF surface after the fire, which restricted the transfer of gas, like oxygen or heat into PU matrix, finally resulting in the promotion of flame retardancy of RPUF. Carbon 149-155 T-box transcription factor 1 Homo sapiens 0-3 26213099-6 2016 Higher energy opposed (C10H8)2 Fe2 structures contain an unprecedented distorted eta(6) ,eta(4) -azulene ligand using six carbon atoms for bonding to one iron atom as a hexahapto fulvene ligand and the remaining four carbon atoms for bonding to the other iron atom as a tetrahapto diene ligand. Carbon 122-128 endothelin receptor type A Homo sapiens 81-84 26213099-6 2016 Higher energy opposed (C10H8)2 Fe2 structures contain an unprecedented distorted eta(6) ,eta(4) -azulene ligand using six carbon atoms for bonding to one iron atom as a hexahapto fulvene ligand and the remaining four carbon atoms for bonding to the other iron atom as a tetrahapto diene ligand. Carbon 122-128 endothelin receptor type A Homo sapiens 89-92 27162978-4 2015 The electrochemically tuned cobalt-nickel-iron oxides grown directly on the three-dimensional carbon fiber electrodes exhibit a low overpotential of 232 mV at current density of 10 mA cm(-2), small Tafel slope of 37.6 mV dec(-1), and exceptional long-term stability of electrolysis for over 100 h in 1 M KOH alkaline medium, superior to most non-noble oxygen evolution catalysts reported so far. Carbon 94-100 deleted in esophageal cancer 1 Homo sapiens 221-227 26213099-6 2016 Higher energy opposed (C10H8)2 Fe2 structures contain an unprecedented distorted eta(6) ,eta(4) -azulene ligand using six carbon atoms for bonding to one iron atom as a hexahapto fulvene ligand and the remaining four carbon atoms for bonding to the other iron atom as a tetrahapto diene ligand. Carbon 217-223 endothelin receptor type A Homo sapiens 81-84 30868869-0 2019 Computational MitoTarget Scanning Based on Topological Vacancies of Single-Walled Carbon Nanotubes with the Human Mitochondrial Voltage-Dependent Anion Channel (hVDAC1). Carbon 82-88 voltage dependent anion channel 1 Homo sapiens 161-167 26213099-6 2016 Higher energy opposed (C10H8)2 Fe2 structures contain an unprecedented distorted eta(6) ,eta(4) -azulene ligand using six carbon atoms for bonding to one iron atom as a hexahapto fulvene ligand and the remaining four carbon atoms for bonding to the other iron atom as a tetrahapto diene ligand. Carbon 217-223 endothelin receptor type A Homo sapiens 89-92 27303693-3 2016 The orthologous Hap2/3/4/5 complex in Saccharomyces cerevisiae exerts a regulatory influence on mitochondrial functions, and Hap4 is subject to glucose repression via the carbon catabolite repressor Mig1. Carbon 171-177 transcription factor MIG1 Saccharomyces cerevisiae S288C 199-203 26203669-7 2015 As an approximation, a spherical core-shell morphology was assumed, and the primary grain size of the carbon black particles was determined to be 74 nm diameter as judged by BET surface area analysis. Carbon 102-108 delta/notch like EGF repeat containing Homo sapiens 174-177 30868869-1 2019 We present an in silico approach for modeling the noncovalent interactions between the human mitochondrial voltage-dependent anion channel (hVDAC1) and a family of single-walled carbon nanotubes (SWCNTs) with a defined pattern of topological vacancies ( v = 1-16), obtained by removing atoms from the SWCNT surface. Carbon 178-184 voltage dependent anion channel 1 Homo sapiens 140-146 26044090-0 2015 ABI1 regulates carbon/nitrogen-nutrient signal transduction independent of ABA biosynthesis and canonical ABA signalling pathways in Arabidopsis. Carbon 15-21 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 26793623-6 2015 Systemic administration of poly I:C mobilized CD11c+, F4/80+, and Gr-1(hi) cells from lamina propria and activated NK cells in the mesenteric lymph nodes (MLN) within 24 h. This innate immune cell rearrangement was type I IFN dependent and mediated through upregulation of TLR4 followed by CCR7 expression in these innate immune cells found in the intestinal mucosa. Carbon 34-35 integrin subunit alpha X Homo sapiens 46-51 30868869-4 2019 In particular, the hVDAC1 residues that can be phosphorylated like Tyr10, Tyr198, and Se16 were significantly perturbed by the interactions with SWCNT with at least nine vacancies. Carbon 145-150 voltage dependent anion channel 1 Homo sapiens 19-25 25822580-4 2015 Co-stimulation with IFN-gamma and the TLR3 ligand poly (I:C) synergistically increased the expression of IFN-beta, IL-6, IL-8, and human beta-defensin-2 in NHEKs compared with poly (I:C) or IFN-gamma alone. Carbon 0-1 toll like receptor 3 Homo sapiens 38-42 25822580-4 2015 Co-stimulation with IFN-gamma and the TLR3 ligand poly (I:C) synergistically increased the expression of IFN-beta, IL-6, IL-8, and human beta-defensin-2 in NHEKs compared with poly (I:C) or IFN-gamma alone. Carbon 0-1 interferon beta 1 Homo sapiens 105-113 26369140-6 2015 Also, a glucose biosensor was prepared using glucose oxidase and EGN-TDZ-Pd placed onto a glassy carbon electrode (GCE). Carbon 97-103 glycine decarboxylase Homo sapiens 115-118 26369155-6 2015 BET surface area of the carbon fibers was increased by about 58% compared with the unmodified fibers. Carbon 24-30 delta/notch like EGF repeat containing Homo sapiens 0-3 30625454-1 2019 The shell/core structure of CDs@CaF2 nanocomposites (CCNCs) were prepared by assembling fluorescent carbon dots (CDs) inside the inorganic CaF2 substrates using co-precipitation interaction. Carbon 100-106 CCR4-NOT transcription complex subunit 8 Homo sapiens 32-36 26373131-3 2015 The physical properties of the prepared Pd/C particles were investigated by BET, XRD, and FE-TEM. Carbon 43-44 delta/notch like EGF repeat containing Homo sapiens 76-79 26644389-7 2016 In contrast, alkyl substitution at C5 resulted in enhanced beta-galactosidase inhibitory activity by a factor of up to 1000, with at least six carbon atoms in the alkyl substituent. Carbon 143-149 galactosidase beta 1 Homo sapiens 59-77 30888368-4 2019 Based on a glassy carbon electrode (GCE) modified with CdS-rGO-C3N4 and a PCB72-binding aptamer (ap/CdS-rGO-C3N4/GCE), a PEC aptasensor for the detection of 2,3",5,5"-tetrachlorobiphenyl (PCB72) was developed. Carbon 18-24 glycine cleavage system protein H Homo sapiens 36-39 26321574-2 2015 EXPERIMENTS: For the first time we imaged the SPR signals upon interaction of a gold surface with seven compounds representing aromatic, cyclic, short chain, and long chain carbon structures using an array format. Carbon 173-179 sepiapterin reductase Homo sapiens 46-49 25482340-1 2015 The steroid hydroxylation and carbon-carbon bond cleavage activities of cytochrome P450 17A1 (CYP17A1) are responsible for the production of glucocorticoids and androgens, respectively. Carbon 30-36 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 72-92 25482340-1 2015 The steroid hydroxylation and carbon-carbon bond cleavage activities of cytochrome P450 17A1 (CYP17A1) are responsible for the production of glucocorticoids and androgens, respectively. Carbon 30-36 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 94-101 25482340-1 2015 The steroid hydroxylation and carbon-carbon bond cleavage activities of cytochrome P450 17A1 (CYP17A1) are responsible for the production of glucocorticoids and androgens, respectively. Carbon 37-43 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 72-92 30830129-0 2019 MOF-derived nitrogen-doped nanoporous carbon for electroreduction of CO2 to CO: the calcining temperature effect and the mechanism. Carbon 38-44 lysine acetyltransferase 8 Homo sapiens 0-3 25482340-1 2015 The steroid hydroxylation and carbon-carbon bond cleavage activities of cytochrome P450 17A1 (CYP17A1) are responsible for the production of glucocorticoids and androgens, respectively. Carbon 37-43 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 94-101 26490174-1 2015 The synthesis of a unique series of long, asymmetric 1-iodopolyynes (1-Cn I and 2-Cn I) with the sp-hybridized carbon chain up to a decapentayne is reported. Carbon 111-117 5'-nucleotidase, cytosolic IA Homo sapiens 71-81 26490174-1 2015 The synthesis of a unique series of long, asymmetric 1-iodopolyynes (1-Cn I and 2-Cn I) with the sp-hybridized carbon chain up to a decapentayne is reported. Carbon 111-117 5'-nucleotidase, cytosolic IA Homo sapiens 71-75 30830129-3 2019 Here, we report the MOF-derived nitrogen-doped nanoporous carbon (NC) as a highly efficient and stable electrocatalyst for the conversion of CO2 to CO. Carbon 58-64 lysine acetyltransferase 8 Homo sapiens 20-23 26112740-7 2015 Promoters induced at low-glucose levels (P(HXT7), P(SSA1) and P(ADH2)) varied in induction strength on non-glucose carbon sources (sucrose, galactose and ethanol); in contrast to the "constitutive" promoters, GFP expression increased as glucose decreased and cells moved towards the diauxic shift. Carbon 115-121 hexose transporter HXT7 Saccharomyces cerevisiae S288C 43-47 30239326-5 2019 Preconsumption food wastes Hpr and WM had more favorable C:N ratios (16.5-17.4) and crude fat contents (4.6-6.5%) as feedstock for composting. Carbon 57-58 haptoglobin-related protein Homo sapiens 27-30 25224484-1 2015 A single enzyme, microsomal P450c17, catalyzes the 17alpha-hydroxylase activity needed to make cortisol and the subsequent 17,20 lyase activity needed to produce the 19-carbon precursors of sex steroids. Carbon 169-175 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 28-35 25846006-7 2015 It was found that AMPK activation had profound effects on the pathways involved in glutamate metabolism since the entrance of the glutamate carbon skeleton into the TCA cycle was reduced. Carbon 140-146 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 18-22 26573531-7 2015 Knock-down of PHF11 resulted in increased interleukin-8 expression and secretion immediately following treatment with poly(I:C), as well as changes in the cellular distribution of membrane-bound and increased nuclear claudin-1 that was observed up to 3 days after the withdrawal of poly(I:C). Carbon 125-126 PHD finger protein 11 Homo sapiens 14-19 30345459-11 2019 CONCLUSIONS: Our data demonstrate that increasing the alpha-carbon chain length of methylone creates "hybrid" transporter compounds which act as DAT blockers but SERT substrates. Carbon 60-66 solute carrier family 6 member 3 Rattus norvegicus 145-148 26248647-4 2015 In the liver, they controls the glucokinase/glucose-6-phosphatase switch and bile acid pool composition, directing carbons to glucose or lipid utilisation, thus providing a unifying mechanism for the two abnormalities of the diabetic liver: excessive glucose production and increased lipid synthesis and secretion. Carbon 115-122 glucose-6-phosphatase catalytic subunit 1 Homo sapiens 44-65 26053003-0 2015 Li1.2Mn0.54Ni0.13Co0.13O2-Encapsulated Carbon Nanofiber Network Cathodes with Improved Stability and Rate Capability for Li-Ion Batteries. Carbon 39-45 transglutaminase 1 Homo sapiens 0-3 30675762-0 2019 Synergistical Coupling Interconnected ZnS/SnS2 Nanoboxes with Polypyrrole-Derived N/S Dual-Doped Carbon for Boosting High-Performance Sodium Storage. Carbon 97-103 sodium voltage-gated channel alpha subunit 11 Homo sapiens 42-46 26053003-1 2015 Li1.2Mn0.54Ni0.13Co0.13O2-encapsulated carbon nanofiber network cathode materials were synthesized by a facile electrospinning method. Carbon 39-45 transglutaminase 1 Homo sapiens 0-3 26344106-5 2015 Then we over-expressed feedback-insensitive alleles of ARO4 encoding 3-deoxy-D-arabino-heptulosonate-7-phosphate and ARO7 encoding chorismate mutase, resulting in production of 4.85 +- 0.31 mg L(-1) resveratrol from glucose as the sole carbon source. Carbon 236-242 3-deoxy-7-phosphoheptulonate synthase ARO4 Saccharomyces cerevisiae S288C 55-59 30675762-3 2019 In this work, binary metal sulfide (ZnS/SnS2 ) nanoboxes confined in N/S dual-doped carbon shell (ZSS@NSC) are fabricated through a facile co-precipitation method involving the wrapping of polypyrrole, and subsequent in situ sulfidation process. Carbon 84-90 sodium voltage-gated channel alpha subunit 11 Homo sapiens 40-44 30675762-5 2019 More significantly, the formation of polypyrrole-derived N/S dual-doped carbon is synergistically coupled with the ZnS/SnS2 to create a unique and robust architecture, further strengthening the interconnect function at the heterointerface, which improves electric/ion transfer and mitigates the volume variation during the long-term cycling process. Carbon 72-78 sodium voltage-gated channel alpha subunit 11 Homo sapiens 119-123 26456915-3 2015 In the biosynthetic pathway of the antibiotic and anti-cancer agent thiostrepton A, TsrM, a B12/rSAM enzyme, catalyses the transfer of a methyl group to an electrophilic carbon atom of tryptophan. Carbon 170-176 TSRM Homo sapiens 84-88 25855336-3 2015 Further UV-vis and photoluminescence analyses show a red shift of the emission peak after repeated EDA treatment, which might be attributed to the formation of imine conjugation from newly formed carbon-nitrogen bonds on the PAN backbone. Carbon 196-202 ectodysplasin A Homo sapiens 99-102 30673278-1 2019 An aqueous two-phase extraction (ATPE) technique capable of separating small-diameter single-walled carbon nanotubes in one, two, or at the most three steps is presented. Carbon 100-106 ATP synthase F1 subunit epsilon Homo sapiens 33-37 25650341-6 2015 Twenty-four differentially expressed proteins were identified in the POS5-overexpressing strain, most of which are related to inositol catabolism, central carbon metabolism, anaplerotic pathway, protein biosynthesis and the stress response. Carbon 155-161 NADH kinase Saccharomyces cerevisiae S288C 69-73 30742182-1 2019 We report on utilizing free-standing hybrid perylenediimide/carbon nanotube (PDI/CNT) films fabricated in air as back contacts for fully inorganic perovskite solar cells (glass/FTO/dense TiO2/mesoporous TiO2/CsPbBr3/back electrode). Carbon 60-66 prolyl 4-hydroxylase subunit beta Homo sapiens 77-80 25795738-0 2015 ABI1 regulates carbon/nitrogen-nutrient signal transduction independent of ABA biosynthesis and canonical ABA signalling pathways in Arabidopsis. Carbon 15-21 Protein phosphatase 2C family protein Arabidopsis thaliana 0-4 26103880-0 2015 miR-370 and miR-373 regulate the pathogenesis of osteoarthritis by modulating one-carbon metabolism via SHMT-2 and MECP-2, respectively. Carbon 82-88 microRNA 370 Homo sapiens 0-7 26103880-0 2015 miR-370 and miR-373 regulate the pathogenesis of osteoarthritis by modulating one-carbon metabolism via SHMT-2 and MECP-2, respectively. Carbon 82-88 microRNA 373 Homo sapiens 12-19 30755061-2 2019 We aimed to characterize the relationship between LDL -C and Lp(a) lowering by evolocumab, a PCSK 9 inhibitor, in a large clinical trial population and to determine the prevalence of concordant/discordant LDL -C and Lp(a) responses to PCSK 9 inhibition. Carbon 54-56 lipoprotein(a) Homo sapiens 61-66 26152564-2 2015 In this work, a new lactam bridge alpha-MSH analog was labeled with (99m)Tc via HYNIC and EDDA/tricine as coligands including gamma aminobutyric acid (GABA) as a three carbon chain spacer between HYNIC and the N-terminus of the cyclic peptide. Carbon 168-174 pro-opiomelanocortin-alpha Mus musculus 34-43 25755254-0 2015 Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable with X-ray irradiation. Carbon 0-6 high mobility group box 1 Homo sapiens 66-91 25755254-2 2015 Here, we examined whether carbon-ion beams, as well as X-rays, can induce HMGB1 release from human cancer cell lines. Carbon 26-32 high mobility group box 1 Homo sapiens 74-79 25755254-8 2015 X-rays and carbon-ion beams significantly increased HMGB1 levels in the culture supernatants of A549, NCI-H460 and WiDr cells at 72 h post-irradiation with a D10 dose. Carbon 11-17 high mobility group box 1 Homo sapiens 52-57 25755254-9 2015 Furthermore, irradiation with X-rays or carbon-ion beams significantly increased HMGB1 levels in the culture supernatants of all five cell lines at 96 h post-irradiation. Carbon 40-46 high mobility group box 1 Homo sapiens 81-86 28788023-3 2015 The hard templated carbon (CMK-3) material had an even higher BET-surface of 1420 m2/g with an average pore size of 4 nm. Carbon 19-25 delta/notch like EGF repeat containing Homo sapiens 62-65 30724936-5 2019 This triple hierarchy multimetal/carbon electrode exhibited remarkable OER activity in an alkaline medium with a small overpotential of 219 mV (vs. RHE) at 10 mA cm-2 and low Tafel slope of 55 mV dec-1. Carbon 33-39 deleted in esophageal cancer 1 Homo sapiens 196-201 28788023-4 2015 The soft templated carbon (SMC) reached a BET-surface of 476 m2/g and a pore size of 7 nm. Carbon 19-25 delta/notch like EGF repeat containing Homo sapiens 42-45 26040265-4 2015 The prepared activated carbon was characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, thermogravimetric-differential thermal analysis, and Brunauer, Emmett, and Teller (BET) surface area. Carbon 23-29 delta/notch like EGF repeat containing Homo sapiens 205-208 26246447-7 2015 Moreover, GOX3 rescues the lethal growth phenotype of a yeast strain lacking CYB2, which cannot grow on l-lactate as a sole carbon source. Carbon 124-130 L-lactate dehydrogenase (cytochrome) Saccharomyces cerevisiae S288C 77-81 30472441-5 2019 N-doped carbon nanotubes (N-CNTs) embellished by ZnCo2O4 quantum dots (ZnCo2O4/N-CNTs) with excellent catalytic properties for the reduction of H2O2 was gotten to act as the label of the antibody-BNP (Ab), providing an obviously current signal through amperometric i-t curve method. Carbon 8-14 natriuretic peptide B Homo sapiens 196-199 26257297-1 2015 The kinetics of Li2 S electrodeposition onto carbon in lithium-sulfur batteries are characterized. Carbon 45-51 ATP binding cassette subfamily A member 12 Homo sapiens 16-19 26211519-3 2015 This in combination with the glucose oxidation at the carbon nanotube/Meldola"s blue/glucose dehydrogenase bioanode can result in a current/or power decrease of BFC in the presence of wild-type p53. Carbon 54-60 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 85-106 26101581-2 2015 Engineered variants of sperm whale myoglobin were found to efficiently catalyze this C-S bond forming transformation across a diverse set of aryl and alkyl mercaptan substrates and alpha-diazoester carbene donors, providing high conversions (60-99%) and high numbers of catalytic turnovers (1,100-5,400). Carbon 85-86 myoglobin Physeter catodon 35-44 25889113-2 2015 The transcription factor CreA/Mig1/CRE-1 is a repressor protein that regulates the use of alternative carbon sources via a mechanism known as Carbon Catabolite Repression (CCR). Carbon 102-108 transcription factor MIG1 Saccharomyces cerevisiae S288C 30-34 30288931-5 2019 The resultant Si/Li2 O-Zn/C trilayer composite film delivers a high reversible capacity of 1536 mAh g-1 after 800 cycles at a current density of 1.0 A g-1 and a long high-rate cycling stability (1400 mAh g-1 after 6000 cycles even at a high current density of 10.0 A g-1 ). Carbon 26-27 ATP binding cassette subfamily A member 12 Homo sapiens 17-20 25873671-8 2015 Taken together, the results suggest that under PEG-induced water stress, GRF9 is involved in allocating more carbon from the shoot to the root and enhancing proton secretion in the root growing zone, and this process is important for root response to mild water stress. Carbon 109-115 general regulatory factor 9 Arabidopsis thaliana 73-77 26062094-4 2015 We identified metal limitation and the alternate carbon source mannose as two environmental indicators likely to be encountered by GAS in the host that significantly induced the Rgg-SHP system. Carbon 49-55 nuclear receptor subfamily 0 group B member 2 Homo sapiens 182-185 30560652-4 2019 A combined experimental and first-principles study reveals that carbon interstitials (CiB) and oxygen vacancies (VO) form CiB-VO pairs which stabilize the tetragonal phase and enhance saturation magnetization. Carbon 64-70 calcium and integrin binding 1 Homo sapiens 86-89 26317641-11 2015 RESULTS: In the carbon ion group, the relative fold increase in COX2 expression was 1.01 in sham-irradiated group (p > 0.05), 3.07 in PBIR (p < 0.05) and 2.50 in WBIR (p < 0.05), respectively, when compared with controls. Carbon 16-22 prostaglandin-endoperoxide synthase 2 Mus musculus 64-68 26317641-16 2015 CONCLUSIONS: Our data show that both carbon and argon ions induced non-targeted, out of field induction of COX2 and DNA damages in breast tissues. Carbon 37-43 prostaglandin-endoperoxide synthase 2 Mus musculus 107-111 25828701-6 2015 TRAF6 is determined to be a direct E3 ligase for GSK3beta, and TRAF6-mediated GSK3beta ubiquitination is essential for poly I:C-dependent cytokine production by promoting the TLR3 adaptor protein TRIF-assembled signalling complex. Carbon 126-127 glycogen synthase kinase 3 beta Homo sapiens 49-57 25828701-6 2015 TRAF6 is determined to be a direct E3 ligase for GSK3beta, and TRAF6-mediated GSK3beta ubiquitination is essential for poly I:C-dependent cytokine production by promoting the TLR3 adaptor protein TRIF-assembled signalling complex. Carbon 126-127 glycogen synthase kinase 3 beta Homo sapiens 78-86 25828701-6 2015 TRAF6 is determined to be a direct E3 ligase for GSK3beta, and TRAF6-mediated GSK3beta ubiquitination is essential for poly I:C-dependent cytokine production by promoting the TLR3 adaptor protein TRIF-assembled signalling complex. Carbon 126-127 toll like receptor 3 Homo sapiens 175-179 30560652-4 2019 A combined experimental and first-principles study reveals that carbon interstitials (CiB) and oxygen vacancies (VO) form CiB-VO pairs which stabilize the tetragonal phase and enhance saturation magnetization. Carbon 64-70 calcium and integrin binding 1 Homo sapiens 122-125 30352372-2 2019 Here, we investigated the interaction of natural PS (extracted from pig"s lungs) with nano carbon particles (NCPs) and anthracene as a representative PAH. Carbon 91-97 phosphatidylinositol glycan anchor biosynthesis class S Sus scrofa 68-73 25811607-12 2015 These analyses also revealed that the content of plastidic 2-C-methyl-D-erythritol 4-phosphate (MEP)-pathway derived cytokinins (CKs) in pgi1 leaves were exceedingly lower than in WT leaves. Carbon 61-62 phosphoglucose isomerase 1 Arabidopsis thaliana 137-141 30565864-2 2019 Herein, flexible Fex Oy /nitrogen-doped carbon films (Fex Oy /NC-MOG) are prepared by facile electrospinning of Fe-based metal-organic gels (MOGs) followed by high-temperature carbonization. Carbon 40-46 myelin oligodendrocyte glycoprotein Homo sapiens 65-68 25679437-3 2015 Moreover, the electrochemical surveys on these Sm@C82 isomers reveal that their redox activities are mainly determined by the properties of their carbon cages. Carbon 146-152 complement C8 beta chain Homo sapiens 50-53 25935284-4 2015 The optimization grouping temperature was 40-110-500 C. The optimum mesoporous carbon sample had the highest BET specific surface area (474 m(2)/g), the largest pore volume (0.46 cm(3)/g), and with reasonable uniform pore size distribution. Carbon 80-86 delta/notch like EGF repeat containing Homo sapiens 110-113 30508484-1 2018 Lightweight and compatible metal-organic framework (MOF)-derived carbon-based composites are widely used in electromagnetic (EM) absorption. Carbon 65-71 lysine acetyltransferase 8 Homo sapiens 27-57 25860940-5 2015 This study adds upregulation of folate-mediated one-carbon metabolism to the known consequences of MYCN amplification, and suggests that this pathway might be targeted in poor outcome tumors with MYCN amplification and high SLC19A1 expression. Carbon 52-58 solute carrier family 19 member 1 Homo sapiens 224-231 25620370-11 2015 Moreover, the carbon-concentrating mechanism-related gene expression revealed that most of them, especially CAH2, LCIB, and HLA3, had remarkable change after 1, 4, and 24 h of the transition, which suggests that Chlorella has similar carbon-concentrating mechanism with Chlamydomonas reinhardtii. Carbon 14-20 uncharacterized protein Chlamydomonas reinhardtii 108-112 25620370-11 2015 Moreover, the carbon-concentrating mechanism-related gene expression revealed that most of them, especially CAH2, LCIB, and HLA3, had remarkable change after 1, 4, and 24 h of the transition, which suggests that Chlorella has similar carbon-concentrating mechanism with Chlamydomonas reinhardtii. Carbon 14-20 uncharacterized protein Chlamydomonas reinhardtii 124-128 30575741-0 2018 Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism. Carbon 84-90 phosphoglycerate dehydrogenase Homo sapiens 25-30 25555224-3 2015 The high BET surface areas of the activated carbons were preserved in the synthesis, and enhanced for one low surface area biochar by dissolving carbonates. Carbon 44-51 delta/notch like EGF repeat containing Homo sapiens 9-12 24962244-6 2015 This interaction starts at just under a nucleophile C-1 separation of 3A and has an incipient bond angle of O-5-C-1-Nuc(O or N) of very close to 90 which can be at C-1 with the p-type orbital at C-1-O-5 of the incipient oxacarbenium ion, that is, the LUMO of the activated donor. Carbon 52-53 nucleobindin 1 Homo sapiens 116-119 25234622-3 2015 The MOF/GO composites have been developed considering both the advantages and drawbacks of the composite components: MOF provided a high porosity and reactive centers and GO a dense array of carbon atoms to increase dispersive interactions. Carbon 191-197 lysine acetyltransferase 8 Homo sapiens 4-7 25921344-5 2015 Based on the surface XPS combined with bulk TGA-MS analysis we were able to evaluate the concentration and type of oxygen-containing functionalities, revealing a high oxygen content for the carbon black. Carbon 190-196 T-box transcription factor 1 Homo sapiens 44-47 24962244-6 2015 This interaction starts at just under a nucleophile C-1 separation of 3A and has an incipient bond angle of O-5-C-1-Nuc(O or N) of very close to 90 which can be at C-1 with the p-type orbital at C-1-O-5 of the incipient oxacarbenium ion, that is, the LUMO of the activated donor. Carbon 112-113 nucleobindin 1 Homo sapiens 116-119 30029123-0 2018 Diffusive gradients in thin films based on MOF-derived porous carbon binding gel for in-situ measurement of antibiotics in waters. Carbon 62-68 lysine acetyltransferase 8 Homo sapiens 43-46 24962244-6 2015 This interaction starts at just under a nucleophile C-1 separation of 3A and has an incipient bond angle of O-5-C-1-Nuc(O or N) of very close to 90 which can be at C-1 with the p-type orbital at C-1-O-5 of the incipient oxacarbenium ion, that is, the LUMO of the activated donor. Carbon 112-113 nucleobindin 1 Homo sapiens 116-119 25792711-9 2015 We also observed significantly higher levels of plasmatic PF4 in abciximab (8.14 +- 1.40 ng/ml; P = 0.004) and enoxaparin groups (8.01 +- 0.80 ng/ml; P = 0.021) compared with the C group (6.45 +- 1.90 ng/ml) but not CD group (8.14 +- 1.40 ng/ml). Carbon 179-180 platelet factor 4 Rattus norvegicus 58-61 30029123-2 2018 Here we developed an approach based on DGT with a novel binding gel using porous carbon material (PCM) derived from metal-organic framework (MOF) for in-situ measurement of antibiotics in water samples. Carbon 81-87 lysine acetyltransferase 8 Homo sapiens 116-145 25531924-0 2015 Carbon nanoscroll from C4H/C4F-type graphene superlattice: MD and MM simulation insights. Carbon 0-6 complement C4B (Chido blood group) Homo sapiens 27-30 30368926-3 2018 Here, a fully synthetic biomimetic membrane is reported that incorporates ultra-efficient 1.5 nm diameter carbon nanotube porin (CNTPs) channels in a block-copolymer matrix. Carbon 106-112 voltage dependent anion channel 1 Homo sapiens 122-127 25756085-2 2015 The as-prepared nanocomposite modified glassy carbon electrode (PdAg NFs/rGO/GCE) showed enhanced catalytic currents and enlarged peak potential separations for the oxidation of ascorbic acid (AA), dopamine (DA), and uric acid (UA) as compared to those of PdAg/GCE, rGO/GCE, commercial Pd/C/GCE, and bare GCE. Carbon 46-52 glycine decarboxylase Homo sapiens 77-80 25756085-2 2015 The as-prepared nanocomposite modified glassy carbon electrode (PdAg NFs/rGO/GCE) showed enhanced catalytic currents and enlarged peak potential separations for the oxidation of ascorbic acid (AA), dopamine (DA), and uric acid (UA) as compared to those of PdAg/GCE, rGO/GCE, commercial Pd/C/GCE, and bare GCE. Carbon 46-52 glycine decarboxylase Homo sapiens 261-264 25756085-2 2015 The as-prepared nanocomposite modified glassy carbon electrode (PdAg NFs/rGO/GCE) showed enhanced catalytic currents and enlarged peak potential separations for the oxidation of ascorbic acid (AA), dopamine (DA), and uric acid (UA) as compared to those of PdAg/GCE, rGO/GCE, commercial Pd/C/GCE, and bare GCE. Carbon 46-52 glycine decarboxylase Homo sapiens 261-264 25756085-2 2015 The as-prepared nanocomposite modified glassy carbon electrode (PdAg NFs/rGO/GCE) showed enhanced catalytic currents and enlarged peak potential separations for the oxidation of ascorbic acid (AA), dopamine (DA), and uric acid (UA) as compared to those of PdAg/GCE, rGO/GCE, commercial Pd/C/GCE, and bare GCE. Carbon 46-52 glycine decarboxylase Homo sapiens 261-264 25756085-2 2015 The as-prepared nanocomposite modified glassy carbon electrode (PdAg NFs/rGO/GCE) showed enhanced catalytic currents and enlarged peak potential separations for the oxidation of ascorbic acid (AA), dopamine (DA), and uric acid (UA) as compared to those of PdAg/GCE, rGO/GCE, commercial Pd/C/GCE, and bare GCE. Carbon 46-52 glycine decarboxylase Homo sapiens 261-264 25490879-3 2015 In the process, the indole unit of L1 is deprotonated by the metal alkyl species and the imino C=N group is transferred to the amido group by alkyl CH2 SiMe3 insertion, affording a new dianionic ligand that bridges two metal alkyl units in mu-eta(2) :eta(1) :eta(1) bonding modes, forming the dinuclear rare-earth metal alkyl complexes. Carbon 95-96 DNA polymerase iota Homo sapiens 243-249 26353700-0 2015 Electrochemical Analysis of Polyethyleneimine- Conductive Carbon Black Supports for Pt-Pd Electrocatalysts. Carbon 58-64 protein tyrosine phosphatase receptor type D Homo sapiens 84-89 30253349-2 2018 The novel bio-nanocomposite of chitosan/activated carbon/iron nanoparticles was synthesized via the sonochemical method and characterized using FTIR, SEM, and BET techniques. Carbon 50-56 delta/notch like EGF repeat containing Homo sapiens 159-162 26353707-9 2015 By combining the photoconductive response of two different carbon nanotubes thin film samples, a straightforward XOR encryption was performed. Carbon 59-65 xanthine dehydrogenase Homo sapiens 113-116 25384893-1 2015 Alkenylboranes R-CH=CH-B(C6F5)2 undergo carbon-carbon coupling by means of 1,1-alkenylboration with diarylphosphino-enynes to give substituted conjugated hexatriene derivatives that bear a vicinal pair of B(C6F5)2 Lewis acid and PAr2 Lewis base functionalities at their central carbon portions. Carbon 40-46 F2R like trypsin receptor 1 Homo sapiens 229-233 25384893-1 2015 Alkenylboranes R-CH=CH-B(C6F5)2 undergo carbon-carbon coupling by means of 1,1-alkenylboration with diarylphosphino-enynes to give substituted conjugated hexatriene derivatives that bear a vicinal pair of B(C6F5)2 Lewis acid and PAr2 Lewis base functionalities at their central carbon portions. Carbon 47-53 F2R like trypsin receptor 1 Homo sapiens 229-233 30346691-0 2018 Hierarchical Carbon@SnS2 Aerogel with "Skeleton/Skin" Architectures as a High-Capacity, High-Rate Capability and Long Cycle Life Anode for Sodium Ion Storage. Carbon 13-19 sodium voltage-gated channel alpha subunit 11 Homo sapiens 20-24 25384893-1 2015 Alkenylboranes R-CH=CH-B(C6F5)2 undergo carbon-carbon coupling by means of 1,1-alkenylboration with diarylphosphino-enynes to give substituted conjugated hexatriene derivatives that bear a vicinal pair of B(C6F5)2 Lewis acid and PAr2 Lewis base functionalities at their central carbon portions. Carbon 47-53 F2R like trypsin receptor 1 Homo sapiens 229-233 25633841-5 2015 Subsequent analysis by NMR showed that GSH had reacted with the acetylene carbon atoms of these mGluR5 PAMs, suggesting a conjugate addition mechanism and implicating cytosolic and microsomal GSH S-transferases (GSTs) in catalysis. Carbon 74-80 glutamate receptor, ionotropic, kainate 1 Mus musculus 96-102 25873671-5 2015 In OE plants, GRF9 favours the allocation of shoot carbon to roots. Carbon 51-57 general regulatory factor 9 Arabidopsis thaliana 14-18 30346691-2 2018 In this work, a highly porous carbon/tin sulfide aerogel with a "skeleton/skin" morphology (SSC@SnS2) has been developed and further used as a binder-free anode for SIBs. Carbon 30-36 sodium voltage-gated channel alpha subunit 11 Homo sapiens 96-100 25862303-4 2015 Sl-ASAT3 was shown to encode an acyl-CoA-dependent acyltransferase that catalyzes the transfer of short (four to five carbons) branched acyl chains to the furanose ring of di-acylsucrose acceptors to produce tri-acylsucroses, which can be further acetylated by Sl-ASAT4 (previously Sl-AT2). Carbon 118-125 acylsugar acyltransferase 3 Solanum lycopersicum 3-8 25608940-1 2015 We determined whether ring-2 carbon of histidine is folate-dependently transferred to carbons 8 (C8) and/or 2 (C2) in urinary uric acid in humans. Carbon 29-35 ring finger protein 2 Homo sapiens 22-28 25608940-1 2015 We determined whether ring-2 carbon of histidine is folate-dependently transferred to carbons 8 (C8) and/or 2 (C2) in urinary uric acid in humans. Carbon 86-93 ring finger protein 2 Homo sapiens 22-28 30265270-4 2018 The temperature coefficient of resistance of our films is much greater than the reported values for pristine carbon nanotubes, up to -2.8% K-1 at liquid nitrogen temperature. Carbon 109-115 keratin 1 Homo sapiens 139-142 25488467-13 2015 The (13)C NMR chemical shifts of the para-carbon of the phenyl probe correlate nicely with SF(CARB), pointing to the reliability of these quantities as measures of long-range substituent effects. Carbon 42-48 syntaxin 8 Homo sapiens 94-98 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 109-116 Acyl-coenzyme A oxidase acox-1.2 Caenorhabditis elegans 233-239 29890394-0 2018 Carbon nanofiber-based multiplexed immunosensor for the detection of survival motor neuron 1, cystic fibrosis transmembrane conductance regulator and Duchenne Muscular Dystrophy proteins. Carbon 0-6 survival of motor neuron 1, telomeric Homo sapiens 69-92 25711678-3 2015 With [RuCl(dppe)2]PF6 the vinylidene salt [RuCl(=C=CHBMIDA)(dppe)2]PF6 is obtained, which reacts with Et3N to afford the neutral alkynyl derivative [Ru(C CBMIDA)Cl(dppe)2]. Carbon 8-9 sperm associated antigen 17 Homo sapiens 18-21 25711678-3 2015 With [RuCl(dppe)2]PF6 the vinylidene salt [RuCl(=C=CHBMIDA)(dppe)2]PF6 is obtained, which reacts with Et3N to afford the neutral alkynyl derivative [Ru(C CBMIDA)Cl(dppe)2]. Carbon 8-9 sperm associated antigen 17 Homo sapiens 67-70 24593890-1 2015 P450c17 enzyme catalyses two different reactions: the 17alpha-hydroxylation of progesterone and pregnenolone, and segmenting the carbon 17-20 binding from the 17,20lyase producing adrenal androgens. Carbon 129-135 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 0-7 29890394-4 2018 Here, we report the development of a disposable carbon nanofiber (CNF)-based electrochemical immunosensor for simultaneous detection of survival motor neuron 1 (SMN1), cystic fibrosis transmembrane conductance regulator (CFTR) and DMD proteins. Carbon 48-54 survival of motor neuron 1, telomeric Homo sapiens 136-159 29890394-4 2018 Here, we report the development of a disposable carbon nanofiber (CNF)-based electrochemical immunosensor for simultaneous detection of survival motor neuron 1 (SMN1), cystic fibrosis transmembrane conductance regulator (CFTR) and DMD proteins. Carbon 48-54 survival of motor neuron 1, telomeric Homo sapiens 161-165 26700591-3 2015 Here, we show that a branched-chain C-20 polyunsaturated fatty acid, geranylgeranoic acid (GGA), induces upregulation of the cellular protein levels of TP53-induced glycolysis and apoptosis regulator (TIGAR) and synthesis of cytochrome c oxidase 2 (SCO2) in human hepatoma-derived HuH-7cells harboring the mutant TP53 gene, suggesting that GGA may shift an energetic state of the tumor cells from aerobic glycolysis to mitochondrial respiration. Carbon 36-37 TP53 induced glycolysis regulatory phosphatase Homo sapiens 152-199 26700591-3 2015 Here, we show that a branched-chain C-20 polyunsaturated fatty acid, geranylgeranoic acid (GGA), induces upregulation of the cellular protein levels of TP53-induced glycolysis and apoptosis regulator (TIGAR) and synthesis of cytochrome c oxidase 2 (SCO2) in human hepatoma-derived HuH-7cells harboring the mutant TP53 gene, suggesting that GGA may shift an energetic state of the tumor cells from aerobic glycolysis to mitochondrial respiration. Carbon 36-37 TP53 induced glycolysis regulatory phosphatase Homo sapiens 201-206 30004027-1 2018 We have demonstrated that large diameter (1.8 +- 0.4 nm) carbon nanotubes (CNTs) can be separated by means of the aqueous two-phase extraction (ATPE). Carbon 57-63 ATP synthase F1 subunit epsilon Homo sapiens 144-148 25646482-9 2015 The combined dataset suggests that TRX may deactivate both mitochondrial succinate dehydrogenase and fumarase and activate the cytosolic ATP-citrate lyase in vivo, acting as a direct regulator of carbon flow through the TCA cycle and providing a mechanism for the coordination of cellular function. Carbon 196-202 thioredoxin H-type 1 Arabidopsis thaliana 35-38 27057553-6 2015 High concentrations of S100A8/A9 and S100A12 were secreted in response to nanoparticles like MSU, silica, TiO2, fullerene, and single-wall carbon nanotubes as well as in response to microbe-derived molecules, such as zymosan or HKCA. Carbon 139-145 S100 calcium binding protein A8 Homo sapiens 23-29 30101417-1 2018 A family of novel imine-N-heterocyclic carbene ruthenium(II) complexes of the general formula [(eta6 -p-cymene)Ru(C^N)Cl]PF6 - (where C^N is an imine-N-heterocyclic carbene chelating ligand with varying substituents) have been prepared and characterized. Carbon 114-115 sperm associated antigen 17 Homo sapiens 121-124 25262292-4 2015 Contrarily, high levels of major ions, organic carbon and trace metals were encountered in the Fez River and the Sebou River downstream the Fez inputs, due to the discharge of urban and industrial untreated and hugely polluted wastewaters. Carbon 47-53 FEZ family zinc finger 1 Homo sapiens 95-98 25625022-2 2015 Currently, the molecular probe FDG, glucose fluorinated with (18)F at the 2-carbon, is the primary metabolic approach for clinical diagnostics with PET imaging. Carbon 76-82 single-strand-selective monofunctional uracil-DNA glycosylase 1 Homo sapiens 31-34 25671108-8 2014 Metabolically, the loss of Sdhb resulted in reprogrammed carbon source utilization and mitochondrial dysfunction. Carbon 57-63 succinate dehydrogenase complex, subunit B, iron sulfur (Ip) Mus musculus 27-31 25512564-5 2014 We investigated the murine HoxD locus with 3C carbon copy (5C) and FISH in different developmental and activity states and in the presence or absence of epigenetic regulators. Carbon 46-52 homeobox D cluster Mus musculus 27-31 25335810-0 2014 Investigation of PF6(-) and TFSI(-) anion intercalation into graphitized carbon blacks and its influence on high voltage lithium ion batteries. Carbon 73-79 sperm associated antigen 17 Homo sapiens 17-20 25335810-6 2014 The intercalation of both PF6(-) and TFSI(-) could be confirmed by cyclic voltammetry in electrodes made of carbon blacks. Carbon 108-114 sperm associated antigen 17 Homo sapiens 26-29 24930695-14 2014 Stimulation of microglia cells with supernatant of Poly I:C-treated RPE cells further elevated IL-6, IL-1ss and Cox2 expression, while it reduced the expression of iNOS. Carbon 58-59 interleukin 6 Sus scrofa 95-99 24930695-14 2014 Stimulation of microglia cells with supernatant of Poly I:C-treated RPE cells further elevated IL-6, IL-1ss and Cox2 expression, while it reduced the expression of iNOS. Carbon 58-59 cytochrome c oxidase subunit II Sus scrofa 112-116 25410248-4 2014 RESULTS: The most interesting finding in this study is that a number of key plant processes were altered in the gln1.3 and gln1.4 mutants, including a number of major biological processes such as carbon metabolism and transport, cell wall metabolism, and several metabolic pathways and stress responsive and regulatory elements. Carbon 196-202 glutamine synthetase root isozyme 3 Zea mays 112-118 25300473-2 2014 The functionalized carbon nanomaterials have been characterized by XPS spectroscopy, electron microscopy (FEG-SEM and TEM), AFM, TGA, and FT-IR to achieve insights on structure, morphology and chemical composition. Carbon 19-25 T-box transcription factor 1 Homo sapiens 129-132 25164881-6 2014 Herein, we report that either a carbon source switch or glucose deprivation results in rapid export of Dbp2 to the cytoplasm. Carbon 32-38 DEAD-box ATP-dependent RNA helicase DBP2 Saccharomyces cerevisiae S288C 103-107 25106027-3 2014 Mucin glycans act as binding sites or carbon sources for the intestinal microbes, thereby functioning as a host-specific determinant affecting the microbiota composition and human health. Carbon 38-44 LOC100508689 Homo sapiens 0-5 24948467-1 2014 Citrate synthase (CS) catalyses the entry of carbon into the citric acid cycle and is highly-conserved structurally across the tree of life. Carbon 45-51 citrate synthase Homo sapiens 0-16 24948467-1 2014 Citrate synthase (CS) catalyses the entry of carbon into the citric acid cycle and is highly-conserved structurally across the tree of life. Carbon 45-51 citrate synthase Homo sapiens 18-20 25188524-1 2014 A nitrogen-doped porous carbon material (N@MOG-C) was prepared by simple pyrolysis of polypyrrole-doped Al-based metal-organic gel (PPy@MOG) at 800 C. The N@MOG-C possessed a uniform three-dimensional (3-D) interconnected mesoporous structure with a high surface area of 1542.6 m(2) g(-1) and a large pore volume of 0.76 cm(3) g(-1). Carbon 24-30 myelin oligodendrocyte glycoprotein Homo sapiens 43-46 25188524-1 2014 A nitrogen-doped porous carbon material (N@MOG-C) was prepared by simple pyrolysis of polypyrrole-doped Al-based metal-organic gel (PPy@MOG) at 800 C. The N@MOG-C possessed a uniform three-dimensional (3-D) interconnected mesoporous structure with a high surface area of 1542.6 m(2) g(-1) and a large pore volume of 0.76 cm(3) g(-1). Carbon 24-30 myelin oligodendrocyte glycoprotein Homo sapiens 136-139 25188524-1 2014 A nitrogen-doped porous carbon material (N@MOG-C) was prepared by simple pyrolysis of polypyrrole-doped Al-based metal-organic gel (PPy@MOG) at 800 C. The N@MOG-C possessed a uniform three-dimensional (3-D) interconnected mesoporous structure with a high surface area of 1542.6 m(2) g(-1) and a large pore volume of 0.76 cm(3) g(-1). Carbon 24-30 myelin oligodendrocyte glycoprotein Homo sapiens 136-139 25188524-3 2014 The doping of nitrogen-endowed N@MOG-C with faster electron transfer kinetics than other carbon materials such as MOG-C, multiwalled carbon nanotubes, and graphene. Carbon 89-95 myelin oligodendrocyte glycoprotein Homo sapiens 33-36 25188524-3 2014 The doping of nitrogen-endowed N@MOG-C with faster electron transfer kinetics than other carbon materials such as MOG-C, multiwalled carbon nanotubes, and graphene. Carbon 133-139 myelin oligodendrocyte glycoprotein Homo sapiens 33-36 25148433-2 2014 The structure of C-dot nanoclusters are confirmed using 1H NMR, FTIR, TEM and TGA. Carbon 17-18 T-box transcription factor 1 Homo sapiens 78-81 25137301-2 2014 Nitrogen adsorption/desorption studies showed that the porous carbon featured a BET surface area as high as 310.8 m(2)/g and a rather broad range of pore size from 5 to 80 nm. Carbon 62-68 delta/notch like EGF repeat containing Homo sapiens 80-83 24716865-4 2014 CS-C immunoreactivity, which represents chondroitin sulfate moieties, was significantly attenuated in the stab-injured cortices of OASIS knockout mice compared to those of wild-type mice. Carbon 0-1 cAMP responsive element binding protein 3-like 1 Mus musculus 131-136 25191340-1 2014 The carbon catabolite repression 4 (CCR4)-negative on TATA-less (NOT) complex serves as one of the major deadenylases of eukaryotes. Carbon 4-10 CCR4-NOT core exoribonuclease subunit CCR4 Saccharomyces cerevisiae S288C 36-40 25177217-0 2014 A multifunctional ribonuclease A-conjugated carbon dot cluster nanosystem for synchronous cancer imaging and therapy. Carbon 44-50 ribonuclease A family member 1, pancreatic Homo sapiens 18-32 25177217-3 2014 Herein, we report for the first time a new strategy to synthesize fluorescent carbon dots (C-dots) with high quantum yields by using ribonuclease A (RNase A) as a biomolecular templating agent under microwave irradiation. Carbon 78-84 ribonuclease A family member 1, pancreatic Homo sapiens 133-147 25177217-3 2014 Herein, we report for the first time a new strategy to synthesize fluorescent carbon dots (C-dots) with high quantum yields by using ribonuclease A (RNase A) as a biomolecular templating agent under microwave irradiation. Carbon 78-84 ribonuclease A family member 1, pancreatic Homo sapiens 149-156 25177217-4 2014 The synthesized RNase A-conjugated carbon dots (RNase A@C-dots) exhibited quantum yields of 24.20%. Carbon 35-41 ribonuclease A family member 1, pancreatic Homo sapiens 16-23 25177217-4 2014 The synthesized RNase A-conjugated carbon dots (RNase A@C-dots) exhibited quantum yields of 24.20%. Carbon 35-41 ribonuclease A family member 1, pancreatic Homo sapiens 48-55 25177217-10 2014 In high pH solution, RNase A tends to form RNase A warped carbon dot nanoclusters. Carbon 58-64 ribonuclease A family member 1, pancreatic Homo sapiens 21-28 25177217-10 2014 In high pH solution, RNase A tends to form RNase A warped carbon dot nanoclusters. Carbon 58-64 ribonuclease A family member 1, pancreatic Homo sapiens 43-50 24850836-4 2014 The (14)C-citrate efflux experiments in oocytes demonstrated that BoMATE is a citrate transporter. Carbon 8-9 MATE efflux family protein 1-like Brassica oleracea 66-72 24983818-2 2014 We have designed a nonsubstrate dUTP analogue with a methylene bridge connecting the alpha phosphate and 5" carbon that potently inhibits SAMHD1. Carbon 108-114 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens 138-144 25744694-3 2015 In this paper, we demonstrate the growth of Aerographite-GaN 3D hybrid networks using ultralight and extremely porous carbon based Aerographite material as templates by a single step hydride vapor phase epitaxy process. Carbon 118-124 gigaxonin Homo sapiens 57-60 25728980-7 2015 Therefore, altered plasma levels of biomarkers related to one-carbon metabolism are associated with NTD-affected pregnancies. Carbon 62-68 fuzzy planar cell polarity protein Homo sapiens 100-103 25588735-8 2015 Interestingly, starch and sucrose accumulation could be prevented and nitrate levels could be maintained by supplying the ppc1/ppc2 mutant with exogenous malate and glutamate, suggesting that low nitrogen status resulted in the alteration of carbon metabolism and prompted the accumulation of starch and sucrose in the ppc1/ppc2 mutant. Carbon 242-248 phosphoenolpyruvate carboxylase 2 Arabidopsis thaliana 324-328 25596184-4 2015 The eceriferum2 (cer2) mutant of Arabidopsis (Arabidopsis thaliana) was previously shown to have a specific deficiency in cuticular waxes longer than 28 carbons, and heterologous expression of CER2 in yeast (Saccharomyces cerevisiae) demonstrated that it can modify the acyl chain length produced by a condensing enzyme from 28 to 30 carbon atoms. Carbon 153-160 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 4-15 25596184-4 2015 The eceriferum2 (cer2) mutant of Arabidopsis (Arabidopsis thaliana) was previously shown to have a specific deficiency in cuticular waxes longer than 28 carbons, and heterologous expression of CER2 in yeast (Saccharomyces cerevisiae) demonstrated that it can modify the acyl chain length produced by a condensing enzyme from 28 to 30 carbon atoms. Carbon 153-160 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 193-197 25596184-4 2015 The eceriferum2 (cer2) mutant of Arabidopsis (Arabidopsis thaliana) was previously shown to have a specific deficiency in cuticular waxes longer than 28 carbons, and heterologous expression of CER2 in yeast (Saccharomyces cerevisiae) demonstrated that it can modify the acyl chain length produced by a condensing enzyme from 28 to 30 carbon atoms. Carbon 153-159 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 4-15 25596184-4 2015 The eceriferum2 (cer2) mutant of Arabidopsis (Arabidopsis thaliana) was previously shown to have a specific deficiency in cuticular waxes longer than 28 carbons, and heterologous expression of CER2 in yeast (Saccharomyces cerevisiae) demonstrated that it can modify the acyl chain length produced by a condensing enzyme from 28 to 30 carbon atoms. Carbon 153-159 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 17-21 25506763-2 2015 Increment in power generation was observed with increase in substrate loading (61-204 mW/m(2)) indicating the ability of anodic bacteria in BET system to utilize the complex chemicals as the sole carbon source. Carbon 196-202 delta/notch like EGF repeat containing Homo sapiens 140-143 25706562-1 2015 Arabidopsis ubiquitin ligases ATL31 and homologue ATL6 control the carbon/nitrogen nutrient and pathogen responses. Carbon 67-73 carbon/nitrogen insensitive 1 Arabidopsis thaliana 30-35 25574779-5 2015 The resulting [Ru(bpy)2(bpy-DPA)Cu](4+)/Nafion/GC sensor exhibits a low ECL signal. Carbon 47-49 apolipoprotein C4 Rattus norvegicus 72-75 25574779-6 2015 The [Ru(bpy)2(bpy-DPA)Cu](4+)/Nafion/GC sensor demonstrates enhanced ECL signal after reacting with volatile H2S due to the high-affinity binding between sulfur and Cu(2+), returning to [Ru(bpy)2(bpy-DPA)](2+)/Nafion/GC. Carbon 37-39 apolipoprotein C4 Rattus norvegicus 69-72 25859101-11 2015 Significant correlation existed between the HbA1c values and both the C: N ratio and average NA in all the three groups. Carbon 70-71 hemoglobin subunit alpha 1 Homo sapiens 44-48 24924927-3 2014 When functionalized with a small amount of carbon nanoparticles, the SnS2 NS-based CE showed even better performance of 8.06 % than Pt under the same conditions. Carbon 43-49 sodium voltage-gated channel alpha subunit 11 Homo sapiens 69-73 29742484-6 2018 A novel electrochemical nonenzymatic sensor for hydrogen peroxide (H2O2) detection is fabricated based on the Ag/Polymer dyes/GS ternary composites modified glass carbon electrode (GCE) for the first time. Carbon 163-169 glycine cleavage system protein H Homo sapiens 181-184 24824655-2 2014 Pyridoxal 5"-phosphate (PLP) serves as a coenzyme in many cellular processes, including several reactions in one-carbon (1C) metabolism and the transsulfuration pathway of homocysteine catabolism. Carbon 113-119 pyridoxal phosphatase Homo sapiens 24-27 31950608-1 2018 This study reports the synthesis of hierarchical NiCoO2 nanosheets growing on hollow carbon spheres (denoted as NiCoO2 NSs@HCS) via a facile and low-cost process. Carbon 85-91 holocarboxylase synthetase Homo sapiens 123-126 24889063-1 2014 Highly photoluminescent carbon nanodots (CNDs) were synthesized for the first time from metal-organic framework (MOF, ZIF-8) nanoparticles. Carbon 24-30 lysine acetyltransferase 8 Homo sapiens 88-123 24895096-1 2014 ZnIn(2)S(4) microspheres (ZIS MSs) were for the first time decorated with carbon quantum dots (CQDs) and platinum nanoparticles (NPs) as dual co-catalysts of for photocatalytic H(2) production. Carbon 74-80 zinc finger RANBP2-type containing 2 Homo sapiens 26-29 24825430-1 2014 A multi-wall carbon nanotube supported Pd and Ni catalyst efficiently catalyzes the hydrogen storage of magnesium hydride prepared by HCS + MM. Carbon 13-19 holocarboxylase synthetase Homo sapiens 134-137 30319543-1 2018 Recent investigations suggest progestin receptor membrane component 1 (PGRMC1) associates with and transports a wide range of molecules such as heme, cytochromes P450, steroids with 21 carbons, membrane progestin receptor alpha (mPRalpha/Paqr7), epidermal growth factor receptor (EGFR), and insulin receptor. Carbon 185-192 progesterone receptor membrane component 1 Danio rerio 30-69 24935936-5 2014 In this study, we show that RNA-binding by the stem cell translation regulator Musashi-1 (MSI1) is allosterically inhibited by 18-22 carbon omega-9 monounsaturated fatty acids. Carbon 133-139 musashi RNA binding protein 1 Homo sapiens 79-88 24935936-5 2014 In this study, we show that RNA-binding by the stem cell translation regulator Musashi-1 (MSI1) is allosterically inhibited by 18-22 carbon omega-9 monounsaturated fatty acids. Carbon 133-139 musashi RNA binding protein 1 Homo sapiens 90-94 30319543-1 2018 Recent investigations suggest progestin receptor membrane component 1 (PGRMC1) associates with and transports a wide range of molecules such as heme, cytochromes P450, steroids with 21 carbons, membrane progestin receptor alpha (mPRalpha/Paqr7), epidermal growth factor receptor (EGFR), and insulin receptor. Carbon 185-192 progesterone receptor membrane component 1 Danio rerio 71-77 26505313-5 2015 In this study, we found that radiation effects evoked by high-LET carbon beam was marked by inhibition of cell viability, cell cycle arrest, significant rise of apoptotic cells, regulation of transcription factor, such as p73, as well as alterations of crucial mediator of the apoptosis pathway. Carbon 66-72 tumor protein p73 Homo sapiens 222-225 30088935-3 2018 Specifically, the amyloid fragments (ba) of beta-lactoglobulin, a whey protein, were deposited onto the surfaces of carbon nanotubes (baCNT), which subsequently sequestered human islet amyloid polypeptide (IAPP) through functional-pathogenic double-protein coronae. Carbon 116-122 islet amyloid polypeptide Homo sapiens 206-210 26390887-5 2015 Carbon-carbon bond cleavage reactions for drug molecules are primarily catalyzed by CYP enzymes, dimerization is mediated by peroxidases, and C-glucuronidation is catalyzed by UGT1A9. Carbon 0-6 UDP glucuronosyltransferase family 1 member A9 Homo sapiens 176-182 24760559-4 2014 Therefore, a method for the determination of carbon isotope ratios (CIRs) of urinary AICAR has been developed and validated. Carbon 45-51 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Homo sapiens 85-90 24767505-2 2014 The mesoporous carbon adsorbents have a high BET specific surface area (1590.3-2193.5 m(2)/g), large pore volume (1.72-2.56 cm(3)/g), and uniform pore size distribution with a median pore diameter ranging from 3.51 nm to 4.52 nm. Carbon 15-21 delta/notch like EGF repeat containing Homo sapiens 45-48 26390887-5 2015 Carbon-carbon bond cleavage reactions for drug molecules are primarily catalyzed by CYP enzymes, dimerization is mediated by peroxidases, and C-glucuronidation is catalyzed by UGT1A9. Carbon 7-13 UDP glucuronosyltransferase family 1 member A9 Homo sapiens 176-182 30113165-8 2018 In one of them, the imine adopts an uncommon eta1(N)eta2(C,N) bridging mode of the ligand to nickel, while the second one may involve reactivity on the ligand by the formation of a new C-C bond by oxidative coupling. Carbon 57-58 DNA polymerase iota Homo sapiens 52-56 24760149-7 2014 The roles of NF-kappaB and IFN regulatory factor-3 (IRF-3) in the poly(I:C)-mediated production of MMPs and the responsiveness to poly(I:C) of normal lung fibroblasts and asthmatic lung fibroblasts were also investigated. Carbon 73-74 interferon regulatory factor 3 Homo sapiens 52-57 25834752-4 2015 Ionization suppression between target perfluorinated analytes and their coeluting SIL-IS were detected for homologues with a number of carbon atoms less than 9, but the quantitation was not affected. Carbon 135-141 STIL centriolar assembly protein Homo sapiens 82-85 30113165-8 2018 In one of them, the imine adopts an uncommon eta1(N)eta2(C,N) bridging mode of the ligand to nickel, while the second one may involve reactivity on the ligand by the formation of a new C-C bond by oxidative coupling. Carbon 185-186 DNA polymerase iota Homo sapiens 52-56 24718808-2 2014 It was demonstrated that introducing diamagnetic gases, such as He, CO2, or N2, under STP conditions to the coal surface induces the appearance of a new type of carbon surface radical. Carbon 161-167 sulfotransferase family 1A member 1 Homo sapiens 86-89 29932987-3 2018 METHODS: We employed a constitutive Alb-Cre-driven rac1 knock-out and a poly I:C-inducible Mx1-Cre-based knock-out model and analyzed cytokine expression profiles in liver and other organs under basal situation and following LPS-induced endotoxemia by flow cytometry, qRT-PCR and immunocytochemistry. Carbon 40-41 albumin Mus musculus 36-39 24971161-6 2013 Carbon cloth electrode ELAT HT 140 E-W with a platinum loading of 5 gm-2 was purchased by E-Tek. Carbon 0-6 TEK receptor tyrosine kinase Homo sapiens 92-95 25663847-6 2014 Distinct enzymes potentially participating in the carbon-concentrating mechanism (CAH7, CAH8, PEPC1) are strongly accumulated. Carbon 50-56 uncharacterized protein Chlamydomonas reinhardtii 88-92 29932987-8 2018 Employing a poly I:C-inducible Mx1-Cre-based rac1 knock-out, which allows a more widespread rac1 deletion in both hepatocytes and non-hepatocytes, we observed substantial differences regarding both basal and LPS-stimulated cytokine expression profiles as compared to the Alb-Cre system. Carbon 19-20 Rac family small GTPase 1 Mus musculus 45-49 25236386-1 2014 For the first time, MOF-derived hierarchically porous carbons with controlled pore structures for on-demand applications have been achieved via a double-template approach. Carbon 54-61 lysine acetyltransferase 8 Homo sapiens 20-23 29932987-8 2018 Employing a poly I:C-inducible Mx1-Cre-based rac1 knock-out, which allows a more widespread rac1 deletion in both hepatocytes and non-hepatocytes, we observed substantial differences regarding both basal and LPS-stimulated cytokine expression profiles as compared to the Alb-Cre system. Carbon 19-20 Rac family small GTPase 1 Mus musculus 92-96 29932987-8 2018 Employing a poly I:C-inducible Mx1-Cre-based rac1 knock-out, which allows a more widespread rac1 deletion in both hepatocytes and non-hepatocytes, we observed substantial differences regarding both basal and LPS-stimulated cytokine expression profiles as compared to the Alb-Cre system. Carbon 19-20 albumin Mus musculus 271-274 24485816-1 2014 The graphitised carbon solid phase extraction (SPE) sorbent Envi-Carb has been used to fabricate glass fibre filter- Envi-Carb "sandwich" disks for use as a passive sampler for acid herbicides. Carbon 16-22 syntaxin 8 Homo sapiens 65-69 30046776-5 2018 This paper reports a new method for carbon-carbon bond formation via the reaction of aroyl chlorides with the TiCl4/NR3 reagent system. Carbon 36-42 glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens 110-119 24485816-1 2014 The graphitised carbon solid phase extraction (SPE) sorbent Envi-Carb has been used to fabricate glass fibre filter- Envi-Carb "sandwich" disks for use as a passive sampler for acid herbicides. Carbon 16-22 syntaxin 8 Homo sapiens 122-126 24760553-7 2014 The approach used to analyze genetic association with the SAM/SAH metabolites is called middle-out: SNPs in 275 genes involved in the one-carbon pathway (folate, pyridoxal/pyridoxine, thiamin) or were correlated with SAM/SAH (vitamin A, E, Hcy) were analyzed instead of the entire 1M SNP data set. Carbon 138-144 acyl-CoA synthetase medium chain family member 3 Homo sapiens 58-65 24760553-7 2014 The approach used to analyze genetic association with the SAM/SAH metabolites is called middle-out: SNPs in 275 genes involved in the one-carbon pathway (folate, pyridoxal/pyridoxine, thiamin) or were correlated with SAM/SAH (vitamin A, E, Hcy) were analyzed instead of the entire 1M SNP data set. Carbon 138-144 acyl-CoA synthetase medium chain family member 3 Homo sapiens 217-224 25044804-2 2014 The BET specific surface area of such carbon is 2341 m(2) g(-1). Carbon 38-44 delta/notch like EGF repeat containing Homo sapiens 4-7 25372486-11 2014 CONCLUSIONS/SIGNIFICANCE: Inhibition of K(Ca)3.1 by EETs (14,15-EET), 20-HETE, and omega3 critically depended on the presence of electron double bonds and hydrophobicity within the 10 carbons preceding the carboxyl-head of the molecules. Carbon 184-191 potassium calcium-activated channel subfamily N member 4 Homo sapiens 40-48 30046776-5 2018 This paper reports a new method for carbon-carbon bond formation via the reaction of aroyl chlorides with the TiCl4/NR3 reagent system. Carbon 43-49 glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens 110-119 24599952-10 2014 The structure reported here is not only the first of any bacterial amidase in which both the PGN component and the water molecule that carries out the nucleophilic attack on the carbonyl carbon of the scissile bond are present; it is also the first peptidoglycan amidase complex structure of an important human pathogen. Carbon 178-184 AT695_RS13185 Staphylococcus aureus 67-74 24599952-10 2014 The structure reported here is not only the first of any bacterial amidase in which both the PGN component and the water molecule that carries out the nucleophilic attack on the carbonyl carbon of the scissile bond are present; it is also the first peptidoglycan amidase complex structure of an important human pathogen. Carbon 178-184 AT695_RS13185 Staphylococcus aureus 263-270 29979016-6 2018 After being integrated by carbon paper, a further improved performance of 198 mV at -200 mA cm-2 and 36 mV dec-1 can be obtained. Carbon 26-32 deleted in esophageal cancer 1 Homo sapiens 107-112 29787815-5 2018 Moreover, when mucin was used as a carbon source, B. breve growth was increased in cocultures with B. bifidum wild-type and Deltasiabb2 strains, suggesting that SiaBb1 may be involved. Carbon 35-41 LOC100508689 Homo sapiens 15-20 24782883-8 2014 Lon1 function is adequately characterized being involved in mitochondrial biogenesis, modulating carbon metabolism, oxidative phosphorylation and energy supply, all prerequisites for seed germination and seedling establishment. Carbon 97-103 lon protease 1 Arabidopsis thaliana 0-4 24706911-4 2014 The structures reveal PhnZ to have an active site containing two Fe ions coordinated by four histidines and two aspartates that is strikingly similar to the carbon-carbon bond cleaving enzyme, myo-inositol-oxygenase. Carbon 157-163 myo-inositol oxygenase Homo sapiens 193-215 24850134-3 2014 In this study, we found that growth of the pho92 strain on SG media was slower than that of the wild type and that PHO92 expression was up-regulated by non-fermentable carbon sources, such as ethanol and glycerol, but not by fermentable carbon sources. Carbon 169-175 mRNA-binding phosphate metabolism regulator Saccharomyces cerevisiae S288C 44-49 24850134-3 2014 In this study, we found that growth of the pho92 strain on SG media was slower than that of the wild type and that PHO92 expression was up-regulated by non-fermentable carbon sources, such as ethanol and glycerol, but not by fermentable carbon sources. Carbon 169-175 mRNA-binding phosphate metabolism regulator Saccharomyces cerevisiae S288C 116-121 24850134-3 2014 In this study, we found that growth of the pho92 strain on SG media was slower than that of the wild type and that PHO92 expression was up-regulated by non-fermentable carbon sources, such as ethanol and glycerol, but not by fermentable carbon sources. Carbon 238-244 mRNA-binding phosphate metabolism regulator Saccharomyces cerevisiae S288C 44-49 24850134-3 2014 In this study, we found that growth of the pho92 strain on SG media was slower than that of the wild type and that PHO92 expression was up-regulated by non-fermentable carbon sources, such as ethanol and glycerol, but not by fermentable carbon sources. Carbon 238-244 mRNA-binding phosphate metabolism regulator Saccharomyces cerevisiae S288C 116-121 24706911-4 2014 The structures reveal PhnZ to have an active site containing two Fe ions coordinated by four histidines and two aspartates that is strikingly similar to the carbon-carbon bond cleaving enzyme, myo-inositol-oxygenase. Carbon 164-170 myo-inositol oxygenase Homo sapiens 193-215 29787815-6 2018 Additionally, B. breve cell numbers increased during cultivation with recombinant SiaBb1-and SiaBb2-treated mucin as the sole carbon source. Carbon 126-132 LOC100508689 Homo sapiens 108-113 29853604-6 2018 Our data identify the helicase/NFkappaB/TNFalpha/COX2 axis as the key suppressive pathway of dsRNA signaling in human TME and suggest that selective targeting of TLR3 or elimination of NFkappaB/TNFalpha/COX2-driven suppression may allow for selective enhancement of type-1 immunity.Significance: This study characterizes two different poly-I:C-induced signaling pathways in their induction of immunostimulatory and suppressive factors and suggests improved ways to reprogram the TME to enhance the antitumor efficacy of immunotherapies. Carbon 49-50 helicase for meiosis 1 Homo sapiens 22-30 23995979-2 2014 In this study, a Dehalobacter species strain TCP1 was isolated from a digester sludge sample, which is able to dechlorinate 2,4,6-trichlorophenol (2,4,6-TCP) to 4-monochlorophenol (4-MCP) with H2 as the sole electron donor and acetate as the carbon source. Carbon 242-248 t-complex 1 Homo sapiens 45-49 25388436-3 2014 The GC-C-IRMS technique (gas chromatography-combustion-isotope ratio mass spectrometry) enables the carbon isotopic ratio (CIR) to be measured to determine the origin of these metabolites. Carbon 100-106 guanylate cyclase 2C Homo sapiens 4-8 25144602-0 2014 Non-covalent double functionalization of carbon nanotubes with a NADH oxidation Ru(II)-based molecular catalyst and a NAD-dependent glucose dehydrogenase. Carbon 41-47 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 132-153 29627528-4 2018 We detected 11 single nucleotide polymorphisms (SNP) of 7 one-carbon metabolism pathway genes (including MTHFR, MTR, MTRR, ALDH1L1, GART, SHMT1 and CBS) in donor livers and analyzed their association with HBV reinfection after liver transplantation. Carbon 62-68 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Homo sapiens 132-136 31458926-3 2018 A Co0.20Fe0.80OOH-coated glassy carbon electrode generated a current density (j) of 10 mA cm-2 at an overpotential (eta) as small as 383 mV (1.61 V vs the reversible hydrogen electrode) in an alkaline electrolyte, with a small Tafel slope of 40 mV dec-1 and excellent durability, whereas pure alpha-FeOOH required eta = 580 mV to reach the same current density. Carbon 32-38 endothelin receptor type A Homo sapiens 116-119 24554504-1 2014 The reaction of 2,3-allenoates and aldehydes in the presence of an alkoxide affords alkyl 4,5-diaryl-3-oxo-2-propylpent-4(E)-enoates and cis-3,4-diaryloxetanes through a formal C=O and C=C metathesis. Carbon 177-178 suppressor of cytokine signaling 3 Homo sapiens 137-142 25078888-1 2014 A novel strategy for the quantitative determination of human colon cancer DLD-1 cells utilizing an electrochemical aptasensor was developed by effective surface recognition between Mucin 1 glycoprotein over-expressed on the cell membrane and MUC-1 aptamer (MUC-1) bound on carbon nanospheres (CNSs). Carbon 273-279 mucin 1, cell surface associated Homo sapiens 181-188 25078888-1 2014 A novel strategy for the quantitative determination of human colon cancer DLD-1 cells utilizing an electrochemical aptasensor was developed by effective surface recognition between Mucin 1 glycoprotein over-expressed on the cell membrane and MUC-1 aptamer (MUC-1) bound on carbon nanospheres (CNSs). Carbon 273-279 mucin 1, cell surface associated Homo sapiens 242-247 25078888-1 2014 A novel strategy for the quantitative determination of human colon cancer DLD-1 cells utilizing an electrochemical aptasensor was developed by effective surface recognition between Mucin 1 glycoprotein over-expressed on the cell membrane and MUC-1 aptamer (MUC-1) bound on carbon nanospheres (CNSs). Carbon 273-279 mucin 1, cell surface associated Homo sapiens 257-262 31458926-3 2018 A Co0.20Fe0.80OOH-coated glassy carbon electrode generated a current density (j) of 10 mA cm-2 at an overpotential (eta) as small as 383 mV (1.61 V vs the reversible hydrogen electrode) in an alkaline electrolyte, with a small Tafel slope of 40 mV dec-1 and excellent durability, whereas pure alpha-FeOOH required eta = 580 mV to reach the same current density. Carbon 32-38 deleted in esophageal cancer 1 Homo sapiens 248-253 24457027-7 2014 On the ssRNA-linked carbon surface, the formation of C3PO oligomers at subnanomolar concentrations likely mimics their assembly onto ssRNA substrates presented by their native partners. Carbon 20-26 translin Homo sapiens 53-57 29992949-6 2018 Remarkably therefore, the TFEB NES integrates carbon (glucose) and nitrogen (amino acid) availability by controlling TFEB flux through a nuclear import-export cycle. Carbon 46-52 transcription factor EB Homo sapiens 26-30 24355692-1 2014 The biologically active form of the B6 vitamers is pyridoxal 5"-phosphate (PLP), which plays a coenzymatic role in several distinct enzymatic activities ranging from the synthesis, interconversion and degradation of amino acids to the replenishment of one-carbon units, synthesis and degradation of biogenic amines, synthesis of tetrapyrrolic compounds and metabolism of amino-sugars. Carbon 256-262 pyridoxal phosphatase Homo sapiens 75-78 29992949-6 2018 Remarkably therefore, the TFEB NES integrates carbon (glucose) and nitrogen (amino acid) availability by controlling TFEB flux through a nuclear import-export cycle. Carbon 46-52 transcription factor EB Homo sapiens 117-121 24700131-11 2014 Using ethanol as carbon source, nitrate (N-NO3(-)) removal efficiency of the bioreactor stood around 80 % for a maximum nitrogen loading rate of approximately 6.5 mg N-NO3 (-) L(-1) h(-1). Carbon 17-23 NNO3 Homo sapiens 41-46 29873477-6 2018 With this strategy, macroporous SCP composites were successfully prepared from hierarchical porous carbon. Carbon 99-105 urocortin 3 Homo sapiens 32-35 25165392-1 2014 BACKGROUND: Pyridoxal 5"-phosphate (PLP) functions as a coenzyme in many cellular processes including one-carbon metabolism and the interconversion and catabolism of amino acids. Carbon 106-112 pyridoxal phosphatase Homo sapiens 36-39 24470522-8 2014 Limiting the generation of reducing equivalent through modulating carbon substrates availability partially restored the NAD(+)/NADH ratio and protected dominant negative Nox4 hearts from ischemic injury. Carbon 66-72 NADPH oxidase 4 Homo sapiens 170-174 29873477-8 2018 Considering the universality of this strategy and the numerous morphologies of carbon materials, this strategy opens many opportunities for making carbon/SCP composites with novel morphologies. Carbon 79-85 urocortin 3 Homo sapiens 154-157 29873477-8 2018 Considering the universality of this strategy and the numerous morphologies of carbon materials, this strategy opens many opportunities for making carbon/SCP composites with novel morphologies. Carbon 147-153 urocortin 3 Homo sapiens 154-157 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 oxoglutarate dehydrogenase Homo sapiens 249-253 24466000-6 2014 Microarray analysis in the absence of any stress showed that deletion of RLM1 in C. albicans significantly down-regulated genes involved in carbohydrate catabolism such as DAK2, GLK4, NHT1 and TPS1, up-regulated genes involved in the utilization of alternative carbon sources, like AGP2, SOU1, SAP6, CIT1 or GAL4, and genes involved in cell adhesion like ECE1, ALS1, ALS3, HWP1 or RBT1. Carbon 261-267 Rlm1p Saccharomyces cerevisiae S288C 73-77 25123929-9 2014 Since increased chromosomal damage resulted in extensive H2AX phosphorylation during polyploidy, we propose that the additional gamma-H2AX during polyploidy incurred by carbon-ion radiation provides a final opportunity for these dangerous and chromosomally unstable cells to be eliminated. Carbon 169-175 H2A.X variant histone Homo sapiens 57-61 25123929-9 2014 Since increased chromosomal damage resulted in extensive H2AX phosphorylation during polyploidy, we propose that the additional gamma-H2AX during polyploidy incurred by carbon-ion radiation provides a final opportunity for these dangerous and chromosomally unstable cells to be eliminated. Carbon 169-175 H2A.X variant histone Homo sapiens 134-138 29636130-0 2018 Dispersion of multi-walled carbon nanotubes in [BMIM]PF6 for electrochemical sensing of acetaminophen. Carbon 27-33 sperm associated antigen 17 Homo sapiens 53-56 25225399-7 2014 DCs from old mice were deficient in poly I:C-stimulated secretion of IL-15, IL-18, and IFN-alpha. Carbon 1-2 interleukin 18 Mus musculus 76-81 25569996-2 2014 The circuit is simulated using a carbon nanotube field-effect transistor SPICE model. Carbon 33-39 spindle and centriole associated protein 1 Homo sapiens 73-78 29934533-6 2018 The best carbon spheres are obtained at 270 C for 7 hours with a reaction concentration of 0.06 g ml-1 and a particle size of 3-6 mum. Carbon 9-15 interleukin 17F Homo sapiens 99-103 25276789-0 2014 The effect of multiwalled carbon nanotubes on hepatotoxicity of Cd2+ in accumulated cadmium-metallothione in mice. Carbon 26-32 CD2 antigen Mus musculus 64-67 24998069-8 2014 The characterization of the magnetic carbons was investigated by various techniques (SEM/EDAX, VSM, BET, FTIR, XRD, DTG) revealing many possible interactions in the carbon-dye system. Carbon 37-44 delta/notch like EGF repeat containing Homo sapiens 100-103 24998069-8 2014 The characterization of the magnetic carbons was investigated by various techniques (SEM/EDAX, VSM, BET, FTIR, XRD, DTG) revealing many possible interactions in the carbon-dye system. Carbon 37-43 delta/notch like EGF repeat containing Homo sapiens 100-103 29967628-6 2018 Consistent with a role for PtdIn-3-phosphate in autophagy, vps38 mutants are hypersensitive to nitrogen and fixed-carbon starvation and show reduced autophagic transport of cargo into vacuoles. Carbon 114-120 Vps38p Saccharomyces cerevisiae S288C 59-64 25064349-1 2014 Synthesis and functionalization strategies of the imidazo[1,2-b]pyrazole core were developed giving a rapid access to three series of novel imidazo[1,2-b]pyrazole type derivatives: C-2/C-6/C-7 trisubstituted, C-2/C-3/C-6 tri(hetero)arylated and C-2/C-3/C-6/C-7 tetrasubstituted imidazo[1,2-b]pyrazoles. Carbon 181-182 complement C6 Homo sapiens 185-188 25064349-1 2014 Synthesis and functionalization strategies of the imidazo[1,2-b]pyrazole core were developed giving a rapid access to three series of novel imidazo[1,2-b]pyrazole type derivatives: C-2/C-6/C-7 trisubstituted, C-2/C-3/C-6 tri(hetero)arylated and C-2/C-3/C-6/C-7 tetrasubstituted imidazo[1,2-b]pyrazoles. Carbon 181-182 complement C6 Homo sapiens 217-220 25064349-1 2014 Synthesis and functionalization strategies of the imidazo[1,2-b]pyrazole core were developed giving a rapid access to three series of novel imidazo[1,2-b]pyrazole type derivatives: C-2/C-6/C-7 trisubstituted, C-2/C-3/C-6 tri(hetero)arylated and C-2/C-3/C-6/C-7 tetrasubstituted imidazo[1,2-b]pyrazoles. Carbon 181-182 complement C6 Homo sapiens 217-220 25137193-3 2014 Herein, we report the electrical monitoring of a prototypical DNA-binding protein, the PvuII restriction enzyme, at microfluidic-encapsulated, DNA-modified carbon nanotube field effect transistors. Carbon 156-162 zinc finger protein 763 Homo sapiens 62-81 24197136-7 2014 In the muscle, HMGB1 addition induced autophagy by decreasing levels of active mTOR and increasing autophagy-associated proteins, plasma glutamate, and (13)C-glutamine incorporation into acetyl-CoA. Carbon 156-157 high mobility group box 1 Mus musculus 15-20 24292069-5 2014 Wnt3a is palmitoylated by fatty acids 13-16 carbons in length at Ser209 but not at Cys77, consistent with a slow turnover rate. Carbon 44-51 Wnt family member 3A Homo sapiens 0-5 29583132-11 2018 However with CA4 treatment higher proportion of cells were in the S-phase while with SWCNT-CA4 treatment greater proportion of cells appeared to be in the G1-phase. Carbon 85-90 carbonic anhydrase 4 Homo sapiens 91-94 24372857-5 2014 Flow cytometric analyses revealed that LPS and poly I:C stimulation allows the CD33(+) CD14(+) HLA-DR(-) subset to be significantly increased. Carbon 54-55 CD14 molecule Homo sapiens 87-91 25044533-1 2014 In the presence of phosphanes (PR3 ), the amido-bridged trinuclear complex [{Ir(mu-NH2 )(tfbb)}3 ] (tfbb=tetrafluorobenzobarrelene) transforms into mononuclear discrete compounds [Ir(1,2-eta(2) -4-kappa-C12 H8 F4 N)(PR3 )3 ], which are the products of the C N coupling between the amido moiety and a vinylic carbon of the diolefin. Carbon 308-314 proteinase 3 Homo sapiens 31-34 29526833-9 2018 P2Y12 reaction unit levels were lower with C-600 mg-12h (group B) than with C-75 mg-24h (group C; P=0.024). Carbon 43-44 purinergic receptor P2Y12 Homo sapiens 0-5 24974776-0 2014 Selective binding of single-stranded DNA-binding proteins onto DNA molecules adsorbed on single-walled carbon nanotubes. Carbon 103-109 small RNA binding exonuclease protection factor La Homo sapiens 21-48 24241823-7 2013 Moreover, we found that the cavity of the SCP2 domains is distinctly formed by carbon atoms, containing neither organized water nor rigid polar interactions with the ligand. Carbon 79-85 sterol carrier protein 2 Homo sapiens 42-46 29526833-9 2018 P2Y12 reaction unit levels were lower with C-600 mg-12h (group B) than with C-75 mg-24h (group C; P=0.024). Carbon 76-77 purinergic receptor P2Y12 Homo sapiens 0-5 24180258-1 2013 We report on a novel sensing platform for H2O2 and glucose based on immobilization of palladium-helical carbon nanofiber (Pd-HCNF) hybrid nanostructures and glucose oxidase (GOx) with Nafion on a glassy carbon electrode (GCE). Carbon 104-110 glycine decarboxylase Homo sapiens 221-224 24974776-1 2014 Single-stranded DNA-binding (SSB) proteins were treated with hybrids of DNA and single-walled carbon nanotubes (SWNTs) to examine the biological function of the DNA molecules adsorbed on the SWNT surface. Carbon 94-100 small RNA binding exonuclease protection factor La Homo sapiens 0-27 24974776-1 2014 Single-stranded DNA-binding (SSB) proteins were treated with hybrids of DNA and single-walled carbon nanotubes (SWNTs) to examine the biological function of the DNA molecules adsorbed on the SWNT surface. Carbon 94-100 small RNA binding exonuclease protection factor La Homo sapiens 29-32 29606600-8 2018 We could show that nanS-p genes of E. coli O104:H4 are responsible for growth inhibition of strain AMC 198, when Neu5,9Ac2 was used as sole carbon source in co-culture. Carbon 140-146 N-acetylneuraminate synthase Bos taurus 19-23 25684783-10 2014 Either way, the SPICE event encompasses two different stages of elevated organic carbon and pyrite burial maintained by high nutrient fluxes to the ocean, and potentially sustained by internal marine geochemical feedbacks. Carbon 81-87 spindle and centriole associated protein 1 Homo sapiens 16-21 24148456-2 2013 The properties of NiZnS nanomaterial loaded on activated carbon (NiZnS-AC) are characterized by FT-IR, TEM, and BET. Carbon 57-63 delta/notch like EGF repeat containing Homo sapiens 112-115 30966638-2 2018 The anodic copolymer with DiCP:cyclopentadithiophene ketone (CPDTK) = 1:1 feed molar ratio showed high transmittance change (DeltaT%) and colouration efficiency (eta), which were measured as 39.5% and 184.1 cm2 C-1 at 1037 nm, respectively. Carbon 28-29 endothelin receptor type A Homo sapiens 162-165 24075304-0 2013 Biotinidase knockout mice show cellular energy deficit and altered carbon metabolism gene expression similar to that of nutritional biotin deprivation: clues for the pathogenesis in the human inherited disorder. Carbon 67-73 biotinidase Mus musculus 0-11 24075304-4 2013 Here we show that a knock-out biotinidase-deficient mouse from a C57BL/6 background that was fed a low biotin diet develops severe ATP deficit with activation of the energy sensor adenosine monophosphate (AMP)-activated protein kinase (AMPK), inhibition of the signaling protein mTOR, driver of protein synthesis and growth, and affecting the expression of central-carbon metabolism genes. Carbon 365-371 biotinidase Mus musculus 30-41 25008153-3 2014 The pex13-4 mutant requires an exogenous source of fixed carbon for pre-photosynthetic development and is resistant to the protoauxin indole-3-butyric acid. Carbon 57-63 peroxin 13 Arabidopsis thaliana 4-9 29846664-5 2018 Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms. Carbon 154-155 calnexin Homo sapiens 85-88 29846664-5 2018 Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms. Carbon 154-155 calnexin Homo sapiens 85-88 29846664-5 2018 Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms. Carbon 154-155 calnexin Homo sapiens 85-88 25072999-2 2014 Titration of the carbon-centered radical, formed following the initial OH abstraction, with oxygen to give HO2 and an imine, followed by conversion of HO2 to OH by reaction with NO, resulted in biexponential OH decay traces on a millisecond time scale. Carbon 17-23 heme oxygenase 2 Homo sapiens 107-110 24204617-4 2013 We showed that although both strains could assimilate mucin monosaccharides, only R. gnavus ATCC 29149 was able to grow on mucin as a sole carbon source. Carbon 139-145 LOC100508689 Homo sapiens 123-128 25072999-2 2014 Titration of the carbon-centered radical, formed following the initial OH abstraction, with oxygen to give HO2 and an imine, followed by conversion of HO2 to OH by reaction with NO, resulted in biexponential OH decay traces on a millisecond time scale. Carbon 17-23 heme oxygenase 2 Homo sapiens 151-154 29717741-0 2018 An ultra-broadband perovskite-PbS quantum dot sensitized carbon nanotube photodetector. Carbon 57-63 cholinergic receptor muscarinic 3 Homo sapiens 30-33 23942835-3 2013 Reductive electropolymerization of these complexes and copolymerization of 4(PF6) and 5(PF6)2 proceeded smoothly, both on glassy carbon and ITO glass electrodes, to afford stable metallopolymeric films with well-defined redox processes. Carbon 129-135 sperm associated antigen 17 Homo sapiens 77-80 23942835-3 2013 Reductive electropolymerization of these complexes and copolymerization of 4(PF6) and 5(PF6)2 proceeded smoothly, both on glassy carbon and ITO glass electrodes, to afford stable metallopolymeric films with well-defined redox processes. Carbon 129-135 sperm associated antigen 17 Homo sapiens 88-91 29671568-2 2018 Recently, a ZJNU-30 metal-organic framework (MOF) has been found to have the potential for adsorption-based separation of olefins and diolefins with four carbon atoms [H. M. Liu et al. Carbon 154-160 lysine acetyltransferase 8 Homo sapiens 12-49 24055874-0 2013 Surface-induced conformational and functional changes of bone morphogenetic protein-2 adsorbed onto single-walled carbon nanotubes. Carbon 114-120 bone morphogenetic protein 2 Homo sapiens 57-85 24998441-7 2014 Overall, our results clearly demonstrated that Tog1 is a newly characterized zinc cluster regulator that functions in the complex network of non-fermentable carbon metabolism in Saccharomyces cerevisiae. Carbon 157-163 Tog1p Saccharomyces cerevisiae S288C 47-51 29694013-2 2018 Hierarchically porous N-doped carbon polyhedrons anchored on crumpled graphene balls (NPC/CGBs) are synthesized by carbonizing a zeolitic imidazolate framework-8 (ZIF-8)/CGB composite precursor, producing an unprecedented effective host matrix for high-performance Li-Se batteries. Carbon 30-36 chorionic gonadotropin subunit beta 5 Homo sapiens 90-93 25115437-4 2014 Because maternal folic acid supplementation reduces human NTD risk in some populations by 60 to 70%, it is likely that NTD predisposition is often associated with a defect in folate-dependent one-carbon metabolism. Carbon 196-202 fuzzy planar cell polarity protein Homo sapiens 119-122 23757326-3 2013 Thermolysis of 8a (R = nPr) proceeded with hydride transfer from a N-isopropyl substituent to the distal carbon atom of the remaining pentynyl unit at boron to give the zwitterionic five-membered heterocyclic product 10a in good yield. Carbon 105-111 neuronal pentraxin receptor Homo sapiens 23-26 29868052-3 2018 In addition to being an essential player in the serine homeostasis, SHMT action is the main source of activated one-carbon units, which links SHMT activity with the control of cell proliferation. Carbon 116-122 serine hydroxymethyltransferase, mitochondrial Medicago truncatula 68-72 23747377-10 2013 The maximum values of local electrophilic reactivity descriptors (fk(+),sk(+),omegak(+)) at vinyl carbon (C6/C22) of (3) indicate that these sites are more prone to nucleophilic attacks. Carbon 98-104 complement C6 Homo sapiens 106-112 23902573-4 2013 With this intermediate, the latter oxidative reactions produce oxyluciferin via proton abstraction at the C4 carbon of LH2-AMP. Carbon 109-115 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 Homo sapiens 119-122 23799512-0 2013 Facile synthesis of a Cu-based MOF confined in macroporous carbon hybrid material with enhanced electrocatalytic ability. Carbon 59-65 lysine acetyltransferase 8 Homo sapiens 31-34 23799512-1 2013 The Cu-based MOF loaded on macroporous carbon (MPC) creates novel Cu-MOF-MPC hybrids for the first time. Carbon 39-45 lysine acetyltransferase 8 Homo sapiens 13-16 23799512-1 2013 The Cu-based MOF loaded on macroporous carbon (MPC) creates novel Cu-MOF-MPC hybrids for the first time. Carbon 39-45 lysine acetyltransferase 8 Homo sapiens 69-72 23743421-5 2013 Comments were made on the role of SNO complex for the interactions between sulfur, nitrogen and carbon metabolisms in anaerobic digestion. Carbon 96-102 strawberry notch homolog 1 Homo sapiens 34-37 23658109-3 2013 The BET surface areas of the resultant activated carbon materials are 2437 (CZIF8a), 1861 (CZIF68a), and 2264 m(2) g(-1) (CZIF69a). Carbon 49-55 delta/notch like EGF repeat containing Homo sapiens 4-7 24028015-4 2013 In the last 30 years, the soil carbon sequestration rate in the 0-20 cm layer was 71.3 kg x (hm2 x a)(-1), and in the past five years, the carbon sequestration rate was 480 kg x (hm x a)(-1). Carbon 31-37 cholinergic receptor muscarinic 2 Homo sapiens 93-96 24028015-5 2013 The recent carbon sequestration rate was higher than the national average soil carbon sequestration rate of the arable layer [380.78 kg x (hm2 x a)(-1)]. Carbon 11-17 cholinergic receptor muscarinic 2 Homo sapiens 139-142 23621575-12 2013 This study suggests that AMP1 modulates ABA, oxidative and abotic stress responses, and is involved in carbon and amino acid metabolism in Arabidopsis. Carbon 103-109 Peptidase M28 family protein Arabidopsis thaliana 25-29 23449395-7 2013 The sensitizing effect of IL-24 on TLR3-induced apoptosis, mediated by influenza A virus or the TLR3-specific agonist poly(I:C), was also evident on tumor spheroids. Carbon 124-126 toll like receptor 3 Homo sapiens 35-39 23449395-7 2013 The sensitizing effect of IL-24 on TLR3-induced apoptosis, mediated by influenza A virus or the TLR3-specific agonist poly(I:C), was also evident on tumor spheroids. Carbon 124-126 toll like receptor 3 Homo sapiens 96-100 23800962-5 2013 In this article, we show that Arabidopsis AMSH1, an AMSH3-related DUB, interacts with the ESCRT-III subunit vacuolar protein sorting2.1 (VPS2.1) and that impairment of both AMSH1 and VPS2.1 causes early senescence and hypersensitivity to artificial carbon starvation in the dark similar to previously reported autophagy mutants. Carbon 249-255 associated molecule with the SH3 domain of STAM 1 Arabidopsis thaliana 42-47 23800962-5 2013 In this article, we show that Arabidopsis AMSH1, an AMSH3-related DUB, interacts with the ESCRT-III subunit vacuolar protein sorting2.1 (VPS2.1) and that impairment of both AMSH1 and VPS2.1 causes early senescence and hypersensitivity to artificial carbon starvation in the dark similar to previously reported autophagy mutants. Carbon 249-255 SNF7 family protein Arabidopsis thaliana 137-143 23553828-0 2013 Hierarchical tubular structures constructed by carbon-coated SnO(2) nanoplates for highly reversible lithium storage. Carbon 47-53 strawberry notch homolog 1 Homo sapiens 61-64 23553828-1 2013 Hierarchical tubular structures constructed by ultrathin carbon-coated SnO(2) nanoplates are rationally designed and synthesized. Carbon 57-63 strawberry notch homolog 1 Homo sapiens 71-74 23553828-3 2013 When evaluated as an anode material for lithium-ion batteries, the as-synthesized SnO(2)-carbon hybrid structure manifests high specific capacity and excellent cycling stability. Carbon 89-95 strawberry notch homolog 1 Homo sapiens 82-85 23737721-4 2013 The BET surface area of the activated carbon is investigated using N2 adsorption at 77 K with selected temperatures of 500, 600, and 700 C. These pyrolysis conditions for preparing the activated carbons are found to yield higher BET surface area at a pyrolysis temperature of 700 C compared to selected commercial activated carbon. Carbon 38-44 delta/notch like EGF repeat containing Homo sapiens 4-7 23737721-4 2013 The BET surface area of the activated carbon is investigated using N2 adsorption at 77 K with selected temperatures of 500, 600, and 700 C. These pyrolysis conditions for preparing the activated carbons are found to yield higher BET surface area at a pyrolysis temperature of 700 C compared to selected commercial activated carbon. Carbon 38-44 delta/notch like EGF repeat containing Homo sapiens 229-232 23737721-4 2013 The BET surface area of the activated carbon is investigated using N2 adsorption at 77 K with selected temperatures of 500, 600, and 700 C. These pyrolysis conditions for preparing the activated carbons are found to yield higher BET surface area at a pyrolysis temperature of 700 C compared to selected commercial activated carbon. Carbon 195-202 delta/notch like EGF repeat containing Homo sapiens 4-7 23737721-4 2013 The BET surface area of the activated carbon is investigated using N2 adsorption at 77 K with selected temperatures of 500, 600, and 700 C. These pyrolysis conditions for preparing the activated carbons are found to yield higher BET surface area at a pyrolysis temperature of 700 C compared to selected commercial activated carbon. Carbon 195-202 delta/notch like EGF repeat containing Homo sapiens 229-232 23737721-4 2013 The BET surface area of the activated carbon is investigated using N2 adsorption at 77 K with selected temperatures of 500, 600, and 700 C. These pyrolysis conditions for preparing the activated carbons are found to yield higher BET surface area at a pyrolysis temperature of 700 C compared to selected commercial activated carbon. Carbon 195-201 delta/notch like EGF repeat containing Homo sapiens 4-7 23737721-4 2013 The BET surface area of the activated carbon is investigated using N2 adsorption at 77 K with selected temperatures of 500, 600, and 700 C. These pyrolysis conditions for preparing the activated carbons are found to yield higher BET surface area at a pyrolysis temperature of 700 C compared to selected commercial activated carbon. Carbon 195-201 delta/notch like EGF repeat containing Homo sapiens 229-232 23320838-9 2013 The phage in group MPP-B contain photosynthesis and carbon metabolism associated genes, while group MPP-A and the outlier P-RSP2 do not, suggesting different constraints on their lytic cycles. Carbon 52-58 peptidase, mitochondrial processing subunit beta Homo sapiens 19-24 23467704-7 2013 Cell surface stimulation of TLR3 with Poly I:C did not affect cell viability but it did activate NF-kappaB activity. Carbon 0-1 toll like receptor 3 Homo sapiens 28-32 23392442-8 2013 MEASUREMENTS AND MAIN RESULTS: An interquartile range elevation in black carbon concentrations (0.97 x 10(-5)/m, equivalent to 0.78 mug/m(3) elemental carbon) was associated with a 6% (95% confidence interval, 2-10%) increase in COPD hospitalizations and a 7% (0-13%) increase in COPD mortality after adjustment for covariates. Carbon 73-79 COPD Homo sapiens 229-233 23392442-8 2013 MEASUREMENTS AND MAIN RESULTS: An interquartile range elevation in black carbon concentrations (0.97 x 10(-5)/m, equivalent to 0.78 mug/m(3) elemental carbon) was associated with a 6% (95% confidence interval, 2-10%) increase in COPD hospitalizations and a 7% (0-13%) increase in COPD mortality after adjustment for covariates. Carbon 73-79 COPD Homo sapiens 280-284 23392442-8 2013 MEASUREMENTS AND MAIN RESULTS: An interquartile range elevation in black carbon concentrations (0.97 x 10(-5)/m, equivalent to 0.78 mug/m(3) elemental carbon) was associated with a 6% (95% confidence interval, 2-10%) increase in COPD hospitalizations and a 7% (0-13%) increase in COPD mortality after adjustment for covariates. Carbon 151-157 COPD Homo sapiens 229-233 23392442-8 2013 MEASUREMENTS AND MAIN RESULTS: An interquartile range elevation in black carbon concentrations (0.97 x 10(-5)/m, equivalent to 0.78 mug/m(3) elemental carbon) was associated with a 6% (95% confidence interval, 2-10%) increase in COPD hospitalizations and a 7% (0-13%) increase in COPD mortality after adjustment for covariates. Carbon 151-157 COPD Homo sapiens 280-284 23083908-0 2013 Carbon nanotubes-nanoflake-like SnS2 nanocomposite for direct electrochemistry of glucose oxidase and glucose sensing. Carbon 0-6 sodium voltage-gated channel alpha subunit 11 Homo sapiens 32-36 23312913-2 2013 A mesoporous carbon adsorbent was synthesized using a soft template method and characterized with TEM, TGA, and nitrogen adsorption/desorption. Carbon 13-19 T-box transcription factor 1 Homo sapiens 103-106 23402213-3 2013 Three peaks due to the branched methyl H(epsilon) proton and its C(eta) carbon observed at 0 C suggested the formation of three rotamers called A, B, and C, based on the presence of the contracted helix and stretched helix forms that have an intrinsic helical pitch. Carbon 72-78 endothelin receptor type A Homo sapiens 67-70 23231091-5 2013 (2)H- and (31)P-electron nuclear double resonance studies, supported by computations, show that the position for hydrogen atom abstraction from 2,5-DAPn and 2,4-DAB by the 5"-deoxyadenosyl radical occurs at the carbon adjacent to the imine, resulting in overstabilized radicals by spin delocalization through the imine into the pyridine ring of PLP. Carbon 211-217 pyridoxal phosphatase Homo sapiens 345-348 23142078-2 2013 We show that glucose and glutamine, by supplying carbons to the TCA cycle to produce ATP, positively feed back to mTORC1 through an AMPK-, TSC1/2-, and Rag-independent mechanism by regulating mTORC1 assembly and its lysosomal localization. Carbon 49-56 CREB regulated transcription coactivator 1 Mus musculus 114-120 25338399-3 2014 The influence of Pb(II) concentration, adsorption time on Pb(II) adsorption on the ethanediamine-modified mesoporous carbon (AC-EDA) was investigated. Carbon 117-123 ectodysplasin A Homo sapiens 128-131 24903104-3 2014 METHODS AND RESULTS: In rats, AT2R activation with intravenous C-21 increased urinary sodium excretion by 10-fold (P<0.0001); this natriuresis was abolished by direct renal interstitial infusion of specific AT2R antagonist PD-123319. Carbon 63-64 angiotensin II receptor, type 2 Rattus norvegicus 30-34 24903104-3 2014 METHODS AND RESULTS: In rats, AT2R activation with intravenous C-21 increased urinary sodium excretion by 10-fold (P<0.0001); this natriuresis was abolished by direct renal interstitial infusion of specific AT2R antagonist PD-123319. Carbon 63-64 angiotensin II receptor, type 2 Rattus norvegicus 210-214 24799562-0 2014 Disruption of the mitochondrial alternative oxidase (AOX) and uncoupling protein (UCP) alters rates of foliar nitrate and carbon assimilation in Arabidopsis thaliana. Carbon 122-128 alternative oxidase 2 Arabidopsis thaliana 32-51 24799562-0 2014 Disruption of the mitochondrial alternative oxidase (AOX) and uncoupling protein (UCP) alters rates of foliar nitrate and carbon assimilation in Arabidopsis thaliana. Carbon 122-128 alternative oxidase 2 Arabidopsis thaliana 53-56 25085153-4 2014 In order to avoid interference from the crystalline IR transparent materials (e.g., CaF2, MgF2, diamond) a 500 mum carbon filled hole is laser drilled in the center of a CaF2 window. Carbon 115-121 CCR4-NOT transcription complex subunit 8 Homo sapiens 170-174 25009547-6 2014 Large-scale transcriptome analyses revealed that ATG8e belongs to a core carbon signaling response shared by Arabidopsis accessions, and the transcription of Arabidopsis ATG7 is tightly co-regulated with genes functioning in chlorophyll degradation and leaf senescence. Carbon 73-79 AUTOPHAGY 8E Arabidopsis thaliana 49-54 24945892-2 2014 The Pseudomonas aeruginosa (PAO1) catabolite repression control protein (Crc) was deemed to act as a translational regulator, repressing functions involved in uptake and utilization of carbon sources. Carbon 185-191 catabolite repression control protein Pseudomonas aeruginosa PAO1 73-76 24893038-5 2014 The application of recombinant VEGF165 stimulated migration in glioma and endothelial cells, which was associated with increased FAK phosphorylation at Tyr861, suggesting that the suppression of cell migration by carbon ion radiation could be via VEGF-activated FAK signaling. Carbon 213-219 protein tyrosine kinase 2 Homo sapiens 129-132 24893038-5 2014 The application of recombinant VEGF165 stimulated migration in glioma and endothelial cells, which was associated with increased FAK phosphorylation at Tyr861, suggesting that the suppression of cell migration by carbon ion radiation could be via VEGF-activated FAK signaling. Carbon 213-219 protein tyrosine kinase 2 Homo sapiens 262-265 24759768-1 2014 The multiple effects of henna plant biomass as a source of carbon, electron donor, and redox mediator (RM) on the enhanced bio-reduction of Orange II (AO7) were investigated. Carbon 59-65 ring finger protein 25 Homo sapiens 151-154 24722992-0 2014 Phosphorylation of Arabidopsis ubiquitin ligase ATL31 is critical for plant carbon/nitrogen nutrient balance response and controls the stability of 14-3-3 proteins. Carbon 76-82 carbon/nitrogen insensitive 1 Arabidopsis thaliana 48-53 24722992-2 2014 We have previously shown that ubiquitin ligase ATL31 regulates plant growth in response to nutrient balance between carbon and nitrogen (C/N) in Arabidopsis. Carbon 116-122 carbon/nitrogen insensitive 1 Arabidopsis thaliana 47-52 24722992-3 2014 Subsequent study demonstrated that ATL31 targets 14-3-3 proteins for ubiquitination and modulates the protein abundance in response to C/N-nutrient status. Carbon 135-136 carbon/nitrogen insensitive 1 Arabidopsis thaliana 35-40 24731137-6 2014 Furthermore, the carbon nanosheets possess BET surface areas in the ~1400-2200 m(2) g(-1) range and electronic conductivities in the range of 1.7-7.4 S cm(-1) (measured at 7.1 MPa). Carbon 17-23 delta/notch like EGF repeat containing Homo sapiens 43-46 24731136-4 2014 A cross-metathesis reaction of the second aminoallylation product with cis-3-hexene is used to elongate the side chain up to 5 carbons so as to prepare the tetraponerines T5 to T8. Carbon 127-134 suppressor of cytokine signaling 3 Homo sapiens 71-76 24584631-1 2014 Carbon-carbon bond cleavage reactions are catalyzed by, among others, lanosterol 14-demethylase (CYP51), cholesterol side-chain cleavage enzyme (CYP11), sterol 17beta-lyase (CYP17), and aromatase (CYP19). Carbon 0-6 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 174-179 24584631-1 2014 Carbon-carbon bond cleavage reactions are catalyzed by, among others, lanosterol 14-demethylase (CYP51), cholesterol side-chain cleavage enzyme (CYP11), sterol 17beta-lyase (CYP17), and aromatase (CYP19). Carbon 7-13 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 174-179 24784297-7 2014 Ag3 turns out to be an exceptional candidate in this regard that undergoes significant structural distortion and has only two of the Ag atoms close to surface C atoms in its lowest energy structure. Carbon 159-160 anterior gradient 3, protein disulphide isomerase family member Homo sapiens 0-3 24530353-0 2014 Epithelial-mesenchymal transition involved in pulmonary fibrosis induced by multi-walled carbon nanotubes via TGF-beta/Smad signaling pathway. Carbon 89-95 transforming growth factor, beta 1 Mus musculus 110-118 24554521-1 2014 A facile, scalable route to new nanocomposites that are based on carbon nanotubes/heteroatom-doped carbon (CNT/HDC) core-sheath nanostructures is reported. Carbon 99-105 histidine decarboxylase Homo sapiens 111-114 24249214-8 2014 The subunits of molecular chaperone T-complex protein 1 and the regulator of mitochondrial one-carbon metabolism MTHFD2 showed negative correlation to productivity. Carbon 95-101 bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial Cricetulus griseus 113-119 24596031-2 2014 The production of biodiesel, in particular, involves the process of upgrading biomass-derived small molecules to diesel precursors containing a specific carbon range (C11 -C23). Carbon 153-159 nucleolin Homo sapiens 172-175 24356583-1 2014 The APEX software predicts the photochemical transformation kinetics of xenobiotics in surface waters as a function of: photoreactivity parameters (direct photolysis quantum yield and second-order reaction rate constants with transient species, namely OH, CO3(-) , (1)O2 and the triplet states of chromophoric dissolved organic matter, (3)CDOM*), water chemistry (nitrate, nitrite, bicarbonate, carbonate, bromide and dissolved organic carbon, DOC), and water depth (more specifically, the optical path length of sunlight in water). Carbon 385-391 apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens 4-8 24551877-0 2014 Post modification of MOF derived carbon via g-C3N4 entrapment for an efficient metal-free oxygen reduction reaction. Carbon 33-39 lysine acetyltransferase 8 Homo sapiens 21-24 24551877-1 2014 High surface area carbon with a nitrogen content of 7.0% is derived from MOF via in situ g-C3N4 formation. Carbon 18-24 lysine acetyltransferase 8 Homo sapiens 73-76 24372694-8 2014 The combined results suggested that the tomato SPA protein plays an important role in plastid metabolism and mediates the source-sink relationships by affecting the rate of carbon translocation to fruits. Carbon 173-179 protein SPA, chloroplastic Solanum lycopersicum 47-50 24562332-2 2014 These enzymes employ radical generating capability of coenzyme B12 (5"-deoxyadenosylcobalamin, dAdoCbl) and ability of pyridoxal-5"-phosphate (PLP, vitamin B6) to stabilize high-energy intermediates for performing challenging 1,2-amino rearrangements between adjacent carbons. Carbon 268-275 pyridoxal phosphatase Homo sapiens 143-146 24410114-0 2014 Asymmetric Friedel-Crafts alkylation of alpha-substituted beta-nitroacrylates: access to beta(2,2)-amino acids bearing indolic all-carbon quaternary stereocenters. Carbon 131-137 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 89-97 23909275-3 2014 The vast majority of compounds that contain a phosphorus-carbon bond are manufactured using phosphorus trichloride (PCl3) as an intermediate. Carbon 57-63 PHD finger protein 19 Homo sapiens 116-120 24247423-3 2014 A resorcinol formaldehyde carbon aerogel was CO2-activated under different conditions and provided aerogels with BET surface areas of 704, 1267 and 2246 m(2) g(-1) and total pore volumes of 0.91, 1.30 and 2.21 mL g(-1), respectively. Carbon 26-32 delta/notch like EGF repeat containing Homo sapiens 113-116 23988655-3 2014 In addition, LC/MS lipidomics analysis of the CMOI-/- embryos showed reduced levels of four phosphatidylcholine and three phosphatidylethanolamine acyl chain species, and of eight triacylglycerol species with four or more unsaturations and fifty-two or more carbons in the acyl chains. Carbon 258-265 beta-carotene oxygenase 1 Mus musculus 46-50 24081383-1 2014 A highly sensitive detection of breast cancer marker, carbohydrate antigen 15-3 (CA 15-3) by carbon nanotube (CNT) based immuno-polymerase chain reaction was reported. Carbon 93-99 mucin 1, cell surface associated Homo sapiens 54-88 24140351-5 2014 The range of concentrations of TCC and TCS in suspended sediments was 0.7-57.3 ng/g and 0.7-13.3 ng/g, respectively, and was closely tied to the quantity of organic carbon in the suspended sediment, which ranged from 1.6 to 14.5%. Carbon 165-171 treacle ribosome biogenesis factor 1 Homo sapiens 39-42 23850787-1 2013 In this study, the preparation of an integrated modified electrode based on the covalent attachment of glucose dehydrogenase (GDH) enzyme and safranin O to amine-derivative multiwalled carbon nanotubes (MWCNTs-NH2) modified glassy carbon (GC) electrode using G2.5-carboxylated PAMAM dendrimer (Den) as linking agent is reported. Carbon 185-191 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 103-124 23850787-1 2013 In this study, the preparation of an integrated modified electrode based on the covalent attachment of glucose dehydrogenase (GDH) enzyme and safranin O to amine-derivative multiwalled carbon nanotubes (MWCNTs-NH2) modified glassy carbon (GC) electrode using G2.5-carboxylated PAMAM dendrimer (Den) as linking agent is reported. Carbon 185-191 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 126-129 23850787-1 2013 In this study, the preparation of an integrated modified electrode based on the covalent attachment of glucose dehydrogenase (GDH) enzyme and safranin O to amine-derivative multiwalled carbon nanotubes (MWCNTs-NH2) modified glassy carbon (GC) electrode using G2.5-carboxylated PAMAM dendrimer (Den) as linking agent is reported. Carbon 231-237 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 103-124 23850787-1 2013 In this study, the preparation of an integrated modified electrode based on the covalent attachment of glucose dehydrogenase (GDH) enzyme and safranin O to amine-derivative multiwalled carbon nanotubes (MWCNTs-NH2) modified glassy carbon (GC) electrode using G2.5-carboxylated PAMAM dendrimer (Den) as linking agent is reported. Carbon 231-237 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 126-129 24245484-5 2013 The binding energy of solute-solute (E11) and solvent-solute (E12) interaction decreases with the increased numbers of carbon atoms in the alcohols. Carbon 119-125 epididymal sperm binding protein 1 Homo sapiens 62-65 23933103-1 2013 The beta-lactoglobulin (beta-LG) protein was discovered to be an efficient and selective dispersant for carbon nanotubes (CTNs) with certain diameters. Carbon 104-110 cystinosin, lysosomal cystine transporter Homo sapiens 122-126 24261829-1 2013 BACKGROUND: Trends in Alaska ecosystem carbon fluxes were predicted from inputs of monthly MODerate resolution Imaging Spectroradiometer (MODIS) vegetation index time-series combined with the NASA-CASA (Carnegie Ames Stanford Approach) carbon cycle simulation model over the past decade. Carbon 39-45 casein alpha s1 Homo sapiens 197-201 24261829-2 2013 CASA simulates monthly net ecosystem production (NEP) as the difference in carbon fluxes between net primary production (NPP) and soil microbial respiration (Rh). Carbon 75-81 casein alpha s1 Homo sapiens 0-4 23933995-9 2013 The up-regulation of AtCGS by light is in agreement with previous studies showing that other enzymes regulating the level of the carbon/amino skeleton and the sulfur group of Met, are up-regulated by light. Carbon 129-135 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein Arabidopsis thaliana 21-26 24113382-3 2013 In the present work, we have used stable isotopically labeled fatty acids differing in carbon length and saturation in cells expressing FATP2 to gain further insights into how this protein functions in fatty acid transport and intracellular fatty acid trafficking. Carbon 87-93 solute carrier family 27 member 2 Homo sapiens 136-141 24286242-9 2013 IL-29 mRNA and protein expression in RA-FLS after stimulation with PGN, poly(I:C), or LPS were measured by real-time PCR and enzyme-linked immunosorbent assay (ELISA), respectively. Carbon 79-80 interferon lambda 1 Homo sapiens 0-5 23959136-1 2013 Formal substitution of the central carbon by silicon within the tetrahedral tetrakis(4-tetrazolylphenyl)methane linker in a copper-based MOF is shown to uniquely influence the structure of the resultant MOF, affecting the orientation of the metal-based nodes and leading to an increase in unit-cell volume and solvent accessible void space. Carbon 35-41 lysine acetyltransferase 8 Homo sapiens 137-140 23959136-1 2013 Formal substitution of the central carbon by silicon within the tetrahedral tetrakis(4-tetrazolylphenyl)methane linker in a copper-based MOF is shown to uniquely influence the structure of the resultant MOF, affecting the orientation of the metal-based nodes and leading to an increase in unit-cell volume and solvent accessible void space. Carbon 35-41 lysine acetyltransferase 8 Homo sapiens 203-206 23939037-1 2013 The EDA-NOCV analysis shows that the singlet 2-adamantylidene is a foiled-type carbene stabilized by the hyperconjugative interaction of one pair of the vicinal C-C sigma-MOs with the empty p-orbital on the carbene carbon atom. Carbon 215-221 ectodysplasin A Homo sapiens 4-7 23930863-6 2013 After that, the nucleophilic sulfur anion of Cys603 in SENP1 attacked the carbonyl carbon of Gly97 of SUMO1 to trigger the reaction, and then a tetrahedral intermediate and an acyl-enzyme intermediate were generated in turn, leading to the final release of enzyme SENP1 and two products, free SUMO1 and RanGAP1. Carbon 74-80 small ubiquitin like modifier 1 Homo sapiens 102-107 23930863-6 2013 After that, the nucleophilic sulfur anion of Cys603 in SENP1 attacked the carbonyl carbon of Gly97 of SUMO1 to trigger the reaction, and then a tetrahedral intermediate and an acyl-enzyme intermediate were generated in turn, leading to the final release of enzyme SENP1 and two products, free SUMO1 and RanGAP1. Carbon 74-80 small ubiquitin like modifier 1 Homo sapiens 293-298 32261116-2 2013 In this study, we developed a carbon nanodot (C-dot)-based miR124a molecular beacon (miR124a CMB). Carbon 30-36 microRNA 124-1 Homo sapiens 59-66 32261116-2 2013 In this study, we developed a carbon nanodot (C-dot)-based miR124a molecular beacon (miR124a CMB). Carbon 30-36 microRNA 124-1 Homo sapiens 85-92 23937148-0 2013 Carbon-sulfur bond formation catalyzed by [Pd(IPr*(OMe))(cin)Cl] (cin = cinnamyl). Carbon 0-6 pyridoxal phosphatase Homo sapiens 57-60 23937148-0 2013 Carbon-sulfur bond formation catalyzed by [Pd(IPr*(OMe))(cin)Cl] (cin = cinnamyl). Carbon 0-6 pyridoxal phosphatase Homo sapiens 66-69 23937148-1 2013 The newly prepared complex [Pd(IPr*(OMe))(cin)(Cl)] provides high catalytic activity for carbon-sulfur cross-coupling reactions. Carbon 89-95 pyridoxal phosphatase Homo sapiens 42-45 23731464-0 2013 The suppressive effect of IL-27 on encephalitogenic Th17 cells induced by multiwalled carbon nanotubes reduces the severity of experimental autoimmune encephalomyelitis. Carbon 86-92 interleukin 27 Homo sapiens 26-31 23731464-7 2013 These results suggest that the increased IL-27 level produced by the APCs incubated with the carbon nanotubes inhibits the development of Th17 cells. Carbon 93-99 interleukin 27 Homo sapiens 41-46 23965176-14 2013 Pre-treatment with poly I:C downregulated NF-kappaB and upregulated IRF3 expression in P5 rat ischemic brains. Carbon 26-27 interferon regulatory factor 3 Rattus norvegicus 68-72 23822586-7 2013 The abstraction from the gamma carbon by HO2 is slowest, although proceeding over the lowest barriers, due to the important influence of transition state entropies. Carbon 31-37 heme oxygenase 2 Homo sapiens 41-44 23607494-8 2013 Furthermore, poly(I:C) and proinflammatory cytokines [(IL-1beta, interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha] induced IL-32 expression strongly in cultured BECs, accompanying the constant expression of TLR-3 and caspase 1. Carbon 20-21 toll like receptor 3 Homo sapiens 220-225 23962883-1 2013 A general review of novel NMR methods to measure heteronuclear long-range proton-carbon coupling constants ((n)JCH; n>1) in small molecules is made. Carbon 81-87 joining chain of multimeric IgA and IgM Homo sapiens 111-114 23728072-1 2013 An unprecedented enantioselective desymmetrization of spiro cyclohexadienone oxindoles has been developed successfully via organocatalyzed asymmetric SMA, which provides facile access to spirocyclic oxindoles bearing a unique all-carbon quaternary stereogenic center with excellent levels of stereoselectivity. Carbon 230-236 survival of motor neuron 1, telomeric Homo sapiens 150-153 23348232-6 2013 RESULTS: Intranasal treatment of poly(I:C) significantly induced airway neutrophilia; production of CXCL1, IFN-beta, and CXCL10; and necrotic cell accumulation in BALF. Carbon 40-41 chemokine (C-X-C motif) ligand 10 Mus musculus 121-127 23670638-0 2013 Carbon and graphene double protection strategy to improve the SnO(x) electrode performance anodes for lithium-ion batteries. Carbon 0-6 strawberry notch homolog 1 Homo sapiens 62-65 23713783-7 2013 Results of the theoretically calculated rate coefficients indicate that the hydrogen abstraction by HO2 from the C2 carbon of both MTHF and DMTHF is the most dominant path among all reaction pathways attributed to its lowest barrier height. Carbon 116-122 heme oxygenase 2 Homo sapiens 100-103 23758938-4 2013 The results showed that high dose of carbon dots could promote the percentages of CD3+ and interferon-gamma (IFN-gamma) secretion and decrease the proportions of CD4+/CD8+ on the first day after administration. Carbon 37-43 CD3 antigen, epsilon polypeptide Mus musculus 82-85 23274194-5 2013 Films prepared by crosslinking [P20-Os(4,4"-dimethoxy-2,2"-bipyridine)2(4-aminomethylpyridine)Cl].PF6, an FAD-dependent glucose dehydrogenase, and carbon nanotubes achieve current densities of 215muAcm(-2) in 5mM glucose at 0.2V vs. Ag/AgCl, showing some promise for application to glucose oxidising biosensors or biofuel cells. Carbon 147-153 sperm associated antigen 17 Homo sapiens 98-101 23274194-5 2013 Films prepared by crosslinking [P20-Os(4,4"-dimethoxy-2,2"-bipyridine)2(4-aminomethylpyridine)Cl].PF6, an FAD-dependent glucose dehydrogenase, and carbon nanotubes achieve current densities of 215muAcm(-2) in 5mM glucose at 0.2V vs. Ag/AgCl, showing some promise for application to glucose oxidising biosensors or biofuel cells. Carbon 147-153 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 120-141 23567677-4 2013 The maximum BET surface area of the obtained activated carbon was found to be around 1779 m(2)/g. Carbon 55-61 delta/notch like EGF repeat containing Homo sapiens 12-15 23530131-7 2013 Heavy isotope-labelling experiments indicates that carbon flux into starch is altered in pgd3 mutants. Carbon 51-57 6-phosphogluconate dehydrogenase, decarboxylating Zea mays 89-93 23447398-1 2013 Treatment of [Cp*(dppe)Fe-C C-TTFMe3] (1) with Ag[PF6] (3 equiv) in DMF provides the binuclear complex [Cp*(dppe)Fe=C=C=TTFMe2 =CH-CH=TTFMe2 =C=C=Fe(dppe)Cp*][PF6]2 (2[PF6 ]2) isolated as a deep-blue powder in 69 % yield. Carbon 14-15 sperm associated antigen 17 Homo sapiens 50-53 23447398-1 2013 Treatment of [Cp*(dppe)Fe-C C-TTFMe3] (1) with Ag[PF6] (3 equiv) in DMF provides the binuclear complex [Cp*(dppe)Fe=C=C=TTFMe2 =CH-CH=TTFMe2 =C=C=Fe(dppe)Cp*][PF6]2 (2[PF6 ]2) isolated as a deep-blue powder in 69 % yield. Carbon 14-15 sperm associated antigen 17 Homo sapiens 159-162 23447398-1 2013 Treatment of [Cp*(dppe)Fe-C C-TTFMe3] (1) with Ag[PF6] (3 equiv) in DMF provides the binuclear complex [Cp*(dppe)Fe=C=C=TTFMe2 =CH-CH=TTFMe2 =C=C=Fe(dppe)Cp*][PF6]2 (2[PF6 ]2) isolated as a deep-blue powder in 69 % yield. Carbon 14-15 sperm associated antigen 17 Homo sapiens 159-162 23447398-2 2013 EPR monitoring of the reaction and comparison of the experimental and calculated EPR spectra allowed the identification of the radical salt [Cp*(dppe)Fe=C=C=TTFMe2 =CH][PF6]2 ([1-CH][PF6]) an intermediate of the reaction, which results from the activation of the methyl group attached in vicinal position with respect to the alkynyl-iron on the TTF ligand by the triple oxidation of 1 leading to its deprotonation by the solvent. Carbon 141-142 sperm associated antigen 17 Homo sapiens 169-172 23447398-2 2013 EPR monitoring of the reaction and comparison of the experimental and calculated EPR spectra allowed the identification of the radical salt [Cp*(dppe)Fe=C=C=TTFMe2 =CH][PF6]2 ([1-CH][PF6]) an intermediate of the reaction, which results from the activation of the methyl group attached in vicinal position with respect to the alkynyl-iron on the TTF ligand by the triple oxidation of 1 leading to its deprotonation by the solvent. Carbon 141-142 sperm associated antigen 17 Homo sapiens 183-186 23447398-2 2013 EPR monitoring of the reaction and comparison of the experimental and calculated EPR spectra allowed the identification of the radical salt [Cp*(dppe)Fe=C=C=TTFMe2 =CH][PF6]2 ([1-CH][PF6]) an intermediate of the reaction, which results from the activation of the methyl group attached in vicinal position with respect to the alkynyl-iron on the TTF ligand by the triple oxidation of 1 leading to its deprotonation by the solvent. Carbon 153-154 sperm associated antigen 17 Homo sapiens 169-172 23447398-2 2013 EPR monitoring of the reaction and comparison of the experimental and calculated EPR spectra allowed the identification of the radical salt [Cp*(dppe)Fe=C=C=TTFMe2 =CH][PF6]2 ([1-CH][PF6]) an intermediate of the reaction, which results from the activation of the methyl group attached in vicinal position with respect to the alkynyl-iron on the TTF ligand by the triple oxidation of 1 leading to its deprotonation by the solvent. Carbon 153-154 sperm associated antigen 17 Homo sapiens 183-186 23447398-3 2013 The dimerization of [1-CH][PF6] through carbon-carbon bond formation provides 2[PF6]2. Carbon 40-46 sperm associated antigen 17 Homo sapiens 27-30 23447398-3 2013 The dimerization of [1-CH][PF6] through carbon-carbon bond formation provides 2[PF6]2. Carbon 40-46 sperm associated antigen 17 Homo sapiens 80-83 23447398-3 2013 The dimerization of [1-CH][PF6] through carbon-carbon bond formation provides 2[PF6]2. Carbon 47-53 sperm associated antigen 17 Homo sapiens 27-30 23447398-3 2013 The dimerization of [1-CH][PF6] through carbon-carbon bond formation provides 2[PF6]2. Carbon 47-53 sperm associated antigen 17 Homo sapiens 80-83 23447398-13 2013 In 2[PF6], the charge and the spin are both symmetrically distributed on the carbon bridge and only moderately on the iron and TTFMe2 electroactive centers. Carbon 77-83 sperm associated antigen 17 Homo sapiens 5-8 23412981-10 2013 Future studies need to examine if epigenetic modifications through the one-carbon cycle contribute to increased levels of MMPs leading to preterm deliveries. Carbon 75-81 matrix metallopeptidase 2 Homo sapiens 122-126 23392407-3 2013 To monitor glucose concentration in tears, glucose dehydrogenase was immobilized on a gold microwire modified with carbon nanotubes and an osmium redox polymer. Carbon 115-121 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 43-64 23537043-1 2013 BACKGROUND: Finely regulating the carbon flux through the glycerol pathway by regulating the expression of the rate controlling enzyme, glycerol-3-phosphate dehydrogenase (GPDH), has been a promising approach to redirect carbon from glycerol to ethanol and thereby increasing the ethanol yield in ethanol production. Carbon 34-40 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 172-176 23537043-1 2013 BACKGROUND: Finely regulating the carbon flux through the glycerol pathway by regulating the expression of the rate controlling enzyme, glycerol-3-phosphate dehydrogenase (GPDH), has been a promising approach to redirect carbon from glycerol to ethanol and thereby increasing the ethanol yield in ethanol production. Carbon 221-227 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 136-170 23537043-1 2013 BACKGROUND: Finely regulating the carbon flux through the glycerol pathway by regulating the expression of the rate controlling enzyme, glycerol-3-phosphate dehydrogenase (GPDH), has been a promising approach to redirect carbon from glycerol to ethanol and thereby increasing the ethanol yield in ethanol production. Carbon 221-227 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 172-176 23497349-14 2013 CONCLUSIONS: We report the first clinical results of patients with HCC undergoing carbon ion therapy using the rasterscanning technique at our institution. Carbon 82-88 HCC Homo sapiens 67-70 23078586-9 2013 Carbon utilization was affected by LuxS, potentially contributing to the observed phenotypic differences. Carbon 0-6 Lutheran suppressor, X-linked Homo sapiens 35-39 23473203-1 2013 We demonstrate that yellow luminescence often observed in both carbon-doped and pristine GaN is the result of electronic transitions via the C(N)-O(N) complex. Carbon 63-69 gigaxonin Homo sapiens 89-92 23276202-7 2013 Also, the amount of managed oil sands CO(2) emissions, and therefore the CCS infrastructure, is very sensitive to the carbon price; significant capture and storage occurs only above 110$/tonne CO(2) in our simulations. Carbon 118-124 copper chaperone for superoxide dismutase Homo sapiens 73-76 22911492-0 2013 In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model. Carbon 23-29 pyruvate carboxylase Mus musculus 83-103 23142511-7 2013 Much higher UV transmittance values (even higher than 80%) can be obtained by dosing powdered activated carbon, which also results in a greater removal of COD. Carbon 104-110 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 155-158 23149626-1 2013 Carbon containing nano-sized molybdenum sulfide composites (MoS(x)C(y)) obtained by thermal decomposition reactions of (R(4)N)(2)MoS(4) (R = -H (C(0)), -CH(3) (C(1)), -C(3)H(7) (C(3)), and -C(6)H(13) (C(6))) show promising performance in visible-light driven photocatalytic hydrogen generation. Carbon 0-6 complement C6 Homo sapiens 189-199 23149626-1 2013 Carbon containing nano-sized molybdenum sulfide composites (MoS(x)C(y)) obtained by thermal decomposition reactions of (R(4)N)(2)MoS(4) (R = -H (C(0)), -CH(3) (C(1)), -C(3)H(7) (C(3)), and -C(6)H(13) (C(6))) show promising performance in visible-light driven photocatalytic hydrogen generation. Carbon 0-6 complement C6 Homo sapiens 190-194 23343389-0 2013 The role of PPARgamma in carbon nanotube-elicited granulomatous lung inflammation. Carbon 25-31 peroxisome proliferator activated receptor gamma Mus musculus 12-21 23142078-1 2013 The metabolism of glucose and glutamine, primary carbon sources utilized by mitochondria to generate energy and macromolecules for cell growth, is directly regulated by mTORC1. Carbon 49-55 CREB regulated transcription coactivator 1 Mus musculus 169-175 23286607-1 2013 We study the growth mechanism of carbon molecules supplied by molecular beam epitaxy on fluoride substrates (MgF2, CaF2, and BaF2). Carbon 33-39 CCR4-NOT transcription complex subunit 8 Homo sapiens 115-119 23862620-5 2013 In the past half decade, deorphanization of several GPCRs has revealed that GPR40, GPR41, GPR43, GPR84 and GPR120 sense concentration of extracellular FFAs with various carbon chain lengths. Carbon 169-175 free fatty acid receptor 4 Homo sapiens 107-113 23160340-3 2013 Cellular responses caused by C-1305 were monitored using DAPI staining, cell cycle analysis, phosphatydilserine externalization analysis and SA-beta-galactosidase expression analysis. Carbon 0-1 beta-galactosidase Cricetulus griseus 144-162 22120669-6 2013 Introduction of a methyl or carboxylate group on the carbon adjacent to the side-chain amide nitrogen in L-gamma-glutamylamine substrates resulted in a dramatic decrease in substrate properties for gGACT thus providing an explanation of why gGACT does not act on L-gamma-glutamyl amino acids except for L-gamma-glutamylglycine. Carbon 53-59 gamma-glutamylaminecyclotransferase Oryctolagus cuniculus 198-203 22120669-6 2013 Introduction of a methyl or carboxylate group on the carbon adjacent to the side-chain amide nitrogen in L-gamma-glutamylamine substrates resulted in a dramatic decrease in substrate properties for gGACT thus providing an explanation of why gGACT does not act on L-gamma-glutamyl amino acids except for L-gamma-glutamylglycine. Carbon 53-59 gamma-glutamylaminecyclotransferase Oryctolagus cuniculus 241-246 22120669-7 2013 Placement of substituents on carbons further removed from the side-chain amide nitrogen in L-gamma-glutamylamines restored activity for gGACT, and L-gamma-glutamylneohexylamine 19 had a higher specificity constant (k(cat) /K(m)) than 1. Carbon 29-36 gamma-glutamylaminecyclotransferase Oryctolagus cuniculus 136-141 22840539-8 2013 Most of the observed 5:3 acid formed bound residues with sediment organic components and can only be quantitatively recovered by post-treatment with NaOH and ENVI-Carb carbon. Carbon 169-175 syntaxin 8 Homo sapiens 163-167 22883110-3 2013 Stable carbon isotope signature was determined by gas chromatography coupled with isotope ratio mass spectrometry through a combustion interface (GC-C-IRMS). Carbon 7-13 guanylate cyclase 2C Homo sapiens 146-150 24007422-6 2013 Besides folate, several other lifestyle and environmental factors as well as genetic variations may influence NTD development, possibly by affecting one-carbon metabolism and thus epigenetic events. Carbon 153-159 fuzzy planar cell polarity protein Homo sapiens 110-113 24039418-0 2013 Nicotinamide-functionalized multiwalled carbon nanotubes increase insulin production in pancreatic beta cells via MIF pathway. Carbon 40-46 macrophage migration inhibitory factor Homo sapiens 114-117 24039425-0 2013 Carbon nanoparticles downregulate expression of basic fibroblast growth factor in the heart during embryogenesis. Carbon 0-6 fibroblast growth factor 2 Gallus gallus 48-78 23040397-4 2012 Glucose dehydrogenase was coated on a carbon electrode to catalyze glucose oxidation in the presence of NAD+ as a cofactor/mediator and methylene green as an electrocatalyst. Carbon 38-44 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 0-21 23033254-4 2012 DMPG-G-MP11-modified glassy carbon electrode (DMPG-G-MP11/GCE) exhibited a pair of well-defined quasi-reversible redox peaks of MP11 and showed high electrocatalytic activity towards hydrogen peroxide (H(2)O(2)). Carbon 28-34 glycine decarboxylase Homo sapiens 46-61 23066636-3 2012 We have shown that biotin and carbon-chain moieties linked to the 3" side, and in select cases the 5" side, of an SSB in the template strand strongly increase the level of transcription arrest when compared to unmodified SSBs. Carbon 30-36 small RNA binding exonuclease protection factor La Homo sapiens 114-117 23066636-4 2012 We also find that a small carbon-chain moiety linked to the upstream side of an SSB aids transcriptional bypass of SSBs for both T7 RNAP and RNAP II. Carbon 26-32 small RNA binding exonuclease protection factor La Homo sapiens 80-83 22791346-3 2012 The ability of this consortium to utilise HMW PAHs such as pyrene and BaP as a sole carbon source in the presence of toxic metal Cd was demonstrated. Carbon 84-90 cilia and flagella associated protein 97 Homo sapiens 42-45 22475642-0 2012 Prostaglandin E2 suppresses poly I: C-stimulated cytokine production via EP2 and EP3 in immortalized human corneal epithelial cells. Carbon 36-37 prostaglandin E receptor 2 Homo sapiens 73-76 22475642-7 2012 The EP2 agonist significantly suppressed the polyI:C-induced expression of CCL5 (P < 0.005), CXCL10 (P < 0.0005), and CXCL11 (P < 0.05) but not of CCL20 and IL-6. Carbon 51-52 prostaglandin E receptor 2 Homo sapiens 4-7 22475642-7 2012 The EP2 agonist significantly suppressed the polyI:C-induced expression of CCL5 (P < 0.005), CXCL10 (P < 0.0005), and CXCL11 (P < 0.05) but not of CCL20 and IL-6. Carbon 51-52 C-C motif chemokine ligand 20 Homo sapiens 156-161 22978605-3 2012 To investigate the mechanisms causing these interesting phenomena, we employed spectroscopic investigations of supported PEM films that were prepared from polystyrene sulfonate (PSS)-wrapped single-walled carbon nanotubes (SWNTs) or pyrene-labeled PSS (PSS-PY) and polydiallyldiammonium chloride. Carbon 205-211 mucin 1, cell surface associated Homo sapiens 121-124 22945375-8 2012 The NHE ligands in the W-2 E complexes are bonded end-on for E=C, Si, and Ge, but side-on for E=Sn and Pb. Carbon 63-64 solute carrier family 9 member C1 Homo sapiens 4-7 22037862-6 2012 In addition, carbon utilization studies were also carried out with bacterial isolates LH1, LH2, and LH4 belonging to the genus Cellulosimicrobium, Bacillus, and Ralstonia, respectively, isolated from the snow samples. Carbon 13-19 LIM homeobox 2 Homo sapiens 91-94 22935373-2 2012 The peptides with a sequence specific to c-Src tyrosine kinase and protein tyrosine phosphatase 1B (PTP1B) were first validated with ELISA-based protein tyrosine kinase assay and then functionalized on vertically aligned carbon nanofiber (VACNF) nanoelectrode arrays (NEAs). Carbon 221-227 C-terminal Src kinase Homo sapiens 41-62 22777948-0 2012 A carbon nanotube toxicity paradigm driven by mast cells and the IL-33/ST2 axis. Carbon 2-8 interleukin 33 Homo sapiens 65-70 22634383-10 2012 Therefore, p65 activation decreases miR-23a expression, which facilitates glutamine consumption allowing leukemic cells to use this alternative source of carbon and favoring their adaptation to the metabolic environment. Carbon 154-160 RELA proto-oncogene, NF-kB subunit Homo sapiens 11-14 22621930-7 2012 An analysis of homology models docked with UDP-sugar donors indicates that Asn-391 in UGT3A1 is able to accommodate the N-acetyl group on C2 of UDP-GlcNAc so that the anomeric carbon atom (C1) is optimally situated for catalysis involving His-35. Carbon 176-182 UDP glycosyltransferase family 3 member A1 Homo sapiens 86-92 22579386-9 2012 Growth on xylose and xylose-fermenting ability were slightly influenced by deletion of NQM1 or TKL2 when xylose was used as the sole carbon source. Carbon 133-139 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate transaldolase NQM1 Saccharomyces cerevisiae S288C 87-91 22113072-6 2012 At the aerobic stage of SND, the simultaneous denitrification could carried out using PHB as the carbon source and N(2)O emission increased because of the slow degradation of PHB. Carbon 97-103 prohibitin 1 Homo sapiens 86-89 22437839-3 2012 These enzymes share high sequence identity and catalyze 4-pro-(R)-hydride transfer from NADPH to an electrophilic carbon but differ in that one residue in the conserved AKR catalytic tetrad, His(120) (AKR1D1 numbering), is substituted by a glutamate in AKR1D1. Carbon 114-120 aldo-keto reductase family 1 member D1 Homo sapiens 253-259 22416269-1 2012 A new type of dehydrogenase-based amperometric glucose biosensor was constructed using glucose dehydrogenase (GDH) which was immobilized on the edge-plane pyrolytic graphite (EPPG) electrode modified with poly(phenosafranin)-functionalized single-walled carbon nanotubes (PPS-SWCNTs). Carbon 254-260 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 87-108 22416269-1 2012 A new type of dehydrogenase-based amperometric glucose biosensor was constructed using glucose dehydrogenase (GDH) which was immobilized on the edge-plane pyrolytic graphite (EPPG) electrode modified with poly(phenosafranin)-functionalized single-walled carbon nanotubes (PPS-SWCNTs). Carbon 254-260 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 110-113 25049605-1 2012 The FAT-1 protein is an n-3 fatty acid desaturase, which can recognize a range of 18- and 20-carbon n-6 substrates and transform n-6 polyunsaturated fatty acids (PUFAs) into n-3 PUFAs while n-3 PUFAs have beneficial effect on human health. Carbon 93-99 FAT atypical cadherin 1 Homo sapiens 4-9 22397825-3 2012 The activated carbon was characterized by SEM, FT-IR, N(2) adsorption and pH(ZPC), and then they were used as adsorbent for removing reactive black 5 from aqueous solution. Carbon 14-20 zona pellucida glycoprotein 3 Homo sapiens 77-80 22708011-1 2012 Electrochemical detection with carbon-fiber microelectrodes has become an established method to monitor directly the release of dopamine from neurons and its uptake by the dopamine transporter. Carbon 31-37 solute carrier family 6 member 3 Rattus norvegicus 172-192 22137531-4 2012 In 6-MAM positive samples, the M/C ratio was greater than unity in 98% (N=917) of the blood samples and 96% (N=665) of the urine samples. Carbon 33-34 sarcoglycan gamma Homo sapiens 5-8 22378245-2 2012 The reaction of three equivalents of the disilylene [LSi-SiL] (1) with two equivalents of ArN=C=NAr in toluene at room temperature for 12 h afforded [LSi(mu-CNAr)(2)SiL] (2) and [LSi(=NAr)-SiL] (3) in a ratio of 1:2. Carbon 94-95 STIL centriolar assembly protein Homo sapiens 57-60 22467566-1 2012 Four- and five-bond heteronuclear J-couplings between the hydrogen H-8 and carbons C-6 and C-2 in a series of 7- and 9-benzyl substituted purine derivaties with variuous substituents in positions 2 and 6 were studied by coupled (13) C NMR and H,C-HMBC experiments and by DFT calculations. Carbon 75-82 complement C6 Homo sapiens 83-86 22242647-3 2012 In this work, we reported a new homogeneous biosensor for MMP-2 based on fluorescence resonance energy transfer (FRET) from upconversion phosphors (UCPs) to carbon nanoparticles (CNPs). Carbon 157-163 matrix metallopeptidase 2 Homo sapiens 58-63 22109881-6 2012 However, as early as 45 min after anti-Fas treatment, we observed upregulation of carbon entry (i.e. flux) from glucose into the Krebs-cycle via pyruvate dehydrogenase (PDH) and pyruvate carboxylase (PC) (up to 139% and 123% of controls, respectively, P < 0.001). Carbon 82-88 pyruvate carboxylase Mus musculus 178-198 22209981-2 2012 In the present study, we demonstrated the polyI:C-induced gene expression of the damage associated molecular pattern (DAMP) molecules S100A8 and S100A9, while other S100 genes were not affected. Carbon 48-49 S100 calcium binding protein A8 Homo sapiens 134-140 22209981-3 2012 Cycloheximide and Brefeldin A treatment revealed both the expression of S100A8 and S100A9 as secondary response genes and the involvement of polyI:C-induced cytokines herein. Carbon 0-1 S100 calcium binding protein A8 Homo sapiens 72-78 22846916-5 2012 Quantitative real-time PCR analyses of 76 genes from several functional classes revealed a carbon starvation transcriptional pattern that includes a partial gluconeogenic response and overexpression of genes encoding non-PTS glucose importers in the strains lacking functional pykA, ptsG or ptsGHI genes. Carbon 91-97 phosphotransferase system (PTS) glucose-specific enzyme IICBA component Bacillus subtilis subsp. subtilis str. 168 283-287 22975061-1 2012 We found in a primary study that ingestion of medium-chain fatty acids (MCFAs) or medium-chain triacylglycerols (MCTs) increased the stomach contents of acyl ghrelin, and we further showed that the carbon-chain length of the acyl groups that modified the nascent ghrelin peptides corresponded to that of the ingested MCFAs or MCTs. Carbon 198-204 appetite-regulating hormone Capra hircus 158-165 22975061-1 2012 We found in a primary study that ingestion of medium-chain fatty acids (MCFAs) or medium-chain triacylglycerols (MCTs) increased the stomach contents of acyl ghrelin, and we further showed that the carbon-chain length of the acyl groups that modified the nascent ghrelin peptides corresponded to that of the ingested MCFAs or MCTs. Carbon 198-204 appetite-regulating hormone Capra hircus 263-270 24246730-5 2013 Introduction of bulky aromatic groups at the carbon linker, as in compounds 13 h-n, dramatically improved the selectivity profiles of hP2X3 when compared with mP2X1 and hP2X7 receptors. Carbon 45-51 purinergic receptor P2X 3 Homo sapiens 134-139 29868052-3 2018 In addition to being an essential player in the serine homeostasis, SHMT action is the main source of activated one-carbon units, which links SHMT activity with the control of cell proliferation. Carbon 116-122 serine hydroxymethyltransferase, mitochondrial Medicago truncatula 142-146 22445076-9 2013 Polyinosinic-polycytidylic acid (poly I:C), which does not signal through MyD88, also induced cell surface CD11c down-regulation. Carbon 40-41 integrin alpha X Mus musculus 107-112 29728593-0 2018 Photoluminescent Cationic Carbon Dots as efficient Non-Viral Delivery of Plasmid SOX9 and Chondrogenesis of Fibroblasts. Carbon 26-32 SRY (sex determining region Y)-box 9 Mus musculus 81-85 23028939-9 2012 Using a multi-walled carbon nanotubes induced peritoneal mesothelioma mouse model, we showed that the SphK1-/- null mice exhibited significantly less inflammation and granulamatous nodules compared to their wild type counterparts. Carbon 21-27 sphingosine kinase 1 Mus musculus 102-107 22916245-9 2012 Specific surface area (BET) of polymer derived carbons can vary between 440 m(2)/g and 250 m(2)/g depending on the amount of porogen used in the synthesis of the AN/DVB polymeric precursors. Carbon 47-54 delta/notch like EGF repeat containing Homo sapiens 23-26 29644372-1 2018 The ability of the carbon nanoring [11]cycloparaphenylene ([11]CPP) for coordinating fullerenes has been tested using a series of hosts, including the pristine fullerenes C60, C70, C76 and C78, the clusterfullerene Sc3N@C80, monometallic endofullerenes Y@C82 and Tm@C82, and dimetallic endofullerenes Y2@C82 and Lu2@C82. Carbon 19-25 complement C8 beta chain Homo sapiens 255-258 22778656-2 2012 Multi-walled carbon nanotubes were functionalized with three different cytochrome P450 isoforms (CYP1A2, CYP2B6, and CYP3A4). Carbon 13-19 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 105-111 29644372-1 2018 The ability of the carbon nanoring [11]cycloparaphenylene ([11]CPP) for coordinating fullerenes has been tested using a series of hosts, including the pristine fullerenes C60, C70, C76 and C78, the clusterfullerene Sc3N@C80, monometallic endofullerenes Y@C82 and Tm@C82, and dimetallic endofullerenes Y2@C82 and Lu2@C82. Carbon 19-25 complement C8 beta chain Homo sapiens 266-269 29644372-1 2018 The ability of the carbon nanoring [11]cycloparaphenylene ([11]CPP) for coordinating fullerenes has been tested using a series of hosts, including the pristine fullerenes C60, C70, C76 and C78, the clusterfullerene Sc3N@C80, monometallic endofullerenes Y@C82 and Tm@C82, and dimetallic endofullerenes Y2@C82 and Lu2@C82. Carbon 19-25 complement C8 beta chain Homo sapiens 266-269 22108293-4 2011 The field emitter fabricated using SnO(2) nanoshuttle arrays has a low turn-on electric field of around 0.6 V microm(-1), and a high field emission current density of above 10 mA cm(-2), which is comparable with the highest emission current density of carbon nanotube and nanowire field emitters. Carbon 252-258 strawberry notch homolog 1 Homo sapiens 35-38 29644372-1 2018 The ability of the carbon nanoring [11]cycloparaphenylene ([11]CPP) for coordinating fullerenes has been tested using a series of hosts, including the pristine fullerenes C60, C70, C76 and C78, the clusterfullerene Sc3N@C80, monometallic endofullerenes Y@C82 and Tm@C82, and dimetallic endofullerenes Y2@C82 and Lu2@C82. Carbon 19-25 complement C8 beta chain Homo sapiens 266-269 29589015-2 2018 NiO/C-HS, with well-dispersed NiO nanosheets supported by carbon hollow spheres, exhibited excellent electrochemical performance. Carbon 58-64 lysosomal trafficking regulator Homo sapiens 4-8 29331812-3 2018 Experiments reveal existence of new weak interactions involving the carbon and pi cloud of the imidazolium aromatic ring with fluoride of PF6 anion (i.e., C2--F-P and pi--F-P) in cmimPF6 but are absent in structurally similar prototype IL, bmimPF6. Carbon 68-74 sperm associated antigen 17 Homo sapiens 138-141 29436035-2 2018 Ultimately, the process provides a straightforward access to beta2,2 -amino acids bearing an all-carbon quaternary stereogenic center in great yields and a high degree of enantioselectivity. Carbon 97-103 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 61-68 29615678-2 2018 Glucose carbon can be diverted from mitochondria by the pentose phosphate pathway (via glucose 6-phosphate dehydrogenase, G6PDH), lactate production (via lactate dehydrogenase, LDH), and rejection of carbon from the TCA cycle (via pyruvate dehydrogenase kinase, PDK), all of which can be upregulated in cancer cells. Carbon 8-14 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 122-127 22036122-4 2011 In the aqueous p-toluenesulfonic acid-d medium, C-6" and C-4" carbons of both alpha, and beta anomeric forms of D-cellobiose are significantly affected by increasing the sulfonic acid concentrations, and this may be due to a 1:1 interaction of p-toluenesulfonic acid-d with the C-6", C-4" region of the cellobiose molecule. Carbon 62-69 complement C6 Homo sapiens 278-281 21866443-1 2011 Glucose, maltose, and mannose as sole carbon sources, induced synthesis of glucose dehydrogenase (GDH) in three strains of Pantoea with specific activities from 0.14 to 0.6 U/mg proteins. Carbon 38-44 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 98-101 21976482-9 2011 It seems that SHM1 and SHM2 operate in a redundant manner in one-carbon metabolism of nonphotorespiring cells with a high demand of one-carbon units; for example, during lignification of vascular cells. Carbon 65-71 serine transhydroxymethyltransferase 1 Arabidopsis thaliana 14-18 21976482-9 2011 It seems that SHM1 and SHM2 operate in a redundant manner in one-carbon metabolism of nonphotorespiring cells with a high demand of one-carbon units; for example, during lignification of vascular cells. Carbon 65-71 serine hydroxymethyltransferase 2 Arabidopsis thaliana 23-27 21976482-9 2011 It seems that SHM1 and SHM2 operate in a redundant manner in one-carbon metabolism of nonphotorespiring cells with a high demand of one-carbon units; for example, during lignification of vascular cells. Carbon 136-142 serine transhydroxymethyltransferase 1 Arabidopsis thaliana 14-18 21976482-9 2011 It seems that SHM1 and SHM2 operate in a redundant manner in one-carbon metabolism of nonphotorespiring cells with a high demand of one-carbon units; for example, during lignification of vascular cells. Carbon 136-142 serine hydroxymethyltransferase 2 Arabidopsis thaliana 23-27 22379801-5 2011 METHODS: By using lactose as the main carbon source and X-Gal as chromogenic agent in the medium, cold-adapted strains producing beta-galactosidase were detected. Carbon 38-44 galactosidase beta 1 Homo sapiens 129-147 21992175-7 2011 The presence of PLN removes the activating effect of PE and shifts SERCA"s activity profile, with a maximal activity reached in bilayers with 20-carbon lipid chain length. Carbon 145-151 phospholamban Homo sapiens 16-19 22024416-3 2011 RESULTS: We present a putative mechanism for robustness in C(4) carbon fixation, involving a key enzyme in the pathway, pyruvate orthophosphate dikinase (PPDK), which is regulated by a bifunctional enzyme, Regulatory Protein (RP). Carbon 64-70 pyruvate, phosphate dikinase 1, chloroplastic Zea mays 154-158 21862579-4 2011 In this study, we found that LPS or poly(I:C)-induced TBK1 activity was significantly reduced in bone marrow-derived macrophage (BMDM) from OPTN(D477N/D477N) mice. Carbon 43-44 TANK-binding kinase 1 Mus musculus 54-58 21847474-4 2011 The ortho-substituted analog [(eta(6)-C(6)H(5))(C(6)H(4)-2-NH(2))]Cr(CO)(3) (3) has an arene-phenyl dihedral angle of 67.70(7) , as determined by single-crystal X-ray crystallography, and 51.9(10) , as determined by DFT calculations. Carbon 38-39 endothelin receptor type A Homo sapiens 31-34 22064646-1 2011 In the title complex, [Pd(C(34)H(33)NP(2))(C(17)H(14)O)], the Pd(0) atom is coordinated in a trigonal planar geometry formed by two P atoms of a bis-[(diphenyl-phosphino)eth-yl]aniline ligand and a C=C (eta(2)) bond involving the C atoms that are in the alpha,beta positions relative to the central ketone of the dibenzyl-ideneacetone ligand. Carbon 26-27 endothelin receptor type A Homo sapiens 203-206 21624033-0 2011 Introduction of the ZmDof1 gene into rice enhances carbon and nitrogen assimilation under low-nitrogen conditions. Carbon 51-57 DNA-binding protein MNB1 Zea mays 20-26 21861510-1 2011 In this study, we successfully prepare SnO(2) nanoparticles inside the pore channels of CMK-3 ordered mesoporous carbon via sonochemical method. Carbon 113-119 strawberry notch homolog 1 Homo sapiens 39-42 21788362-3 2011 In addition both enzymes play a role in the breakdown of cellular carbon storage reserves with isovaleryl-CoA dehydrogenase being involved in degradation of the branched-chain amino acids, phytol, and lysine while 2-hydroxyglutarate dehydrogenase is exclusively involved in lysine degradation. Carbon 66-72 isovaleryl-CoA-dehydrogenase Arabidopsis thaliana 95-123 21751788-1 2011 In this work, with a zeolite-type metal-organic framework as both a precursor and a template and furfuryl alcohol as a second precursor, nanoporous carbon material has been prepared with an unexpectedly high surface area (3405 m(2)/g, BET method) and considerable hydrogen storage capacity (2.77 wt % at 77 K and 1 atm) as well as good electrochemical properties as an electrode material for electric double layer capacitors. Carbon 148-154 delta/notch like EGF repeat containing Homo sapiens 235-238 21652715-4 2011 We show here the involvement of the Ser/Thr kinase HpNpr1 in Ynt1 phosphorylation and regulation of Ynt1 levels in response to nitrogen source quality and the availability of carbon. Carbon 175-181 proteasome regulatory particle base subunit RPT3 Saccharomyces cerevisiae S288C 61-65 21652715-4 2011 We show here the involvement of the Ser/Thr kinase HpNpr1 in Ynt1 phosphorylation and regulation of Ynt1 levels in response to nitrogen source quality and the availability of carbon. Carbon 175-181 proteasome regulatory particle base subunit RPT3 Saccharomyces cerevisiae S288C 100-104 21652715-12 2011 We concluded that Npr1 plays a key role in adapting Ynt1 levels to the nitrogen quality and availability of a source of carbon. Carbon 120-126 proteasome regulatory particle base subunit RPT3 Saccharomyces cerevisiae S288C 52-56 22091087-1 2011 In the title salt, C(23)H(23)N(2)O(+) PF(6) (-), the PF(6) (-) anion is highly disordered (occupancy ratios of 0.35:0.35:0.3, 0.7:0.15:0.15, 0.7:0.3 and 0.35:0.35:0.15:0.15) with the four F atoms in the equatorial plane rotating about the axial F-P-F bond. Carbon 19-20 sperm associated antigen 17 Homo sapiens 53-58 22020112-4 2011 The carnitine/acylcarnitine carrier transports carnitine and acylcarnitines with acyl chains of various lengths from 2 to 18 carbon atoms. Carbon 125-131 solute carrier family 25 member 20 Homo sapiens 4-35 23190757-0 2013 Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration. Carbon 80-86 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 8-14 24146625-0 2013 The bacterial response regulator ArcA uses a diverse binding site architecture to regulate carbon oxidation globally. Carbon 91-97 arginine deiminase Escherichia coli 33-37 24146625-7 2013 We propose that this plasticity in ArcA binding site architecture provides both an efficient means of encoding binding sites for ArcA, sigma(70)-RNAP and perhaps other transcription factors within the same narrow sequence space and an effective mechanism for global control of carbon metabolism to maintain redox homeostasis. Carbon 277-283 arginine deiminase Escherichia coli 35-39 24146625-7 2013 We propose that this plasticity in ArcA binding site architecture provides both an efficient means of encoding binding sites for ArcA, sigma(70)-RNAP and perhaps other transcription factors within the same narrow sequence space and an effective mechanism for global control of carbon metabolism to maintain redox homeostasis. Carbon 277-283 arginine deiminase Escherichia coli 129-133 29226424-10 2018 Activation of EP2 receptor reversed the Poly(I:C)/LPS-induced phosphorylation of the mitogen activated protein kinases (MAPKs) ERK, p38 MAPK and c-Jun N-terminal kinase (JNK) in microglia. Carbon 47-48 prostaglandin E receptor 2 Homo sapiens 14-17 22858003-0 2012 Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorn delivered siRNA. Carbon 106-112 cofilin 1 Homo sapiens 93-102 29615218-14 2018 Black carbon exposure was associated with elevated promoter methylation in APEX1 (9 16%, 4 06 to 14 25, p=0 01) and ERCC4 (27 56%, 17 58 to 37 55, p<0 0001). Carbon 6-12 apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens 75-80 22961131-6 2012 Analysis of the zmccd8 mutant revealed a modest increase in branching that contrasted with prominent pleiotropic changes that include (1) marked reduction in stem diameter, (2) reduced elongation of internodes (independent of carbon supply), and (3) a pronounced delay in development of the centrally important, nodal system of adventitious roots. Carbon 226-232 carotenoid cleavage dioxygenase Zea mays 16-22 29533781-1 2018 Expression of PKM2, which diverts glucose-derived carbon from catabolic to biosynthetic pathways, is a hallmark of cancer. Carbon 50-56 pyruvate kinase, muscle Mus musculus 14-18 22968828-7 2012 Collectively, the evidence suggests that loss of Lon1 significantly modifies respiratory function and plant performance by small but broad alterations in the mitochondrial proteome gained by subtly changing steady-state protein assembly, stability, and damage of a range of components that debilitate an anaplerotic role for mitochondria in cellular carbon metabolism. Carbon 350-356 lon protease 1 Arabidopsis thaliana 49-53 22983398-0 2012 Highly electrically conductive layered carbon derived from polydopamine and its functions in SnO2-based lithium ion battery anodes. Carbon 39-45 strawberry notch homolog 1 Homo sapiens 93-96 29504566-9 2018 The presence of carbon in the carbide phase improves the corrosion resistance of the Mg1.52Li0.24Al0.24C0.86 alloy compared to the ternary Mg1.52Li0.24Al0.24 alloy and Mg. Carbon 16-22 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 85-88 22904303-4 2012 Polyinosinic-polycytidylic acid [Poly (I:C)], a dsRNA receptor ligand, activates Rac via its guanine nucleotide exchange factor Tiam; this leads to the activation of cytokine genes and, paradoxically, downregulation of the Tipe2 gene. Carbon 41-43 tumor necrosis factor, alpha-induced protein 8-like 2 Mus musculus 223-228 29504566-9 2018 The presence of carbon in the carbide phase improves the corrosion resistance of the Mg1.52Li0.24Al0.24C0.86 alloy compared to the ternary Mg1.52Li0.24Al0.24 alloy and Mg. Carbon 16-22 mucin 5B, oligomeric mucus/gel-forming Homo sapiens 139-142 29055080-6 2018 The matrix equation exactly reproduces litter and soil organic carbon (SOC) dynamics of the standard CLM4.5 across different spatial-temporal scales. Carbon 63-69 CD300 molecule like family member d Homo sapiens 101-105 29417117-4 2018 Significantly, due to the introduction of the low-melting Mg2+, the Mg-Co MOFs could be further utilized as precursors for porous carbons only by calcination at a mild temperature of 600 C which could exhibit a BET surface as high as 712.78 m2 g-1. Carbon 130-137 delta/notch like EGF repeat containing Homo sapiens 212-215 29357218-3 2018 Herein, oxygen-doped carbon on the surface of reduced graphene oxide (labeled as ODC/rGO) was fabricated to modify the separators of Li-S batteries to limit the dissolution of the lithium polysulfides. Carbon 21-27 ornithine decarboxylase 1 Homo sapiens 81-84 29416063-0 2018 AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. Carbon 84-90 aryl hydrocarbon receptor Homo sapiens 0-3 29416063-0 2018 AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. Carbon 84-90 nuclear receptor subfamily 0 group B member 2 Homo sapiens 8-11 29283561-3 2018 However, the subsequent 17,20 carbon-carbon scission reaction displays variable substrate specificity in the numerous CYP17A1 isozymes operating in vertebrates, manifesting as different Kd and kcat values when presented with 17alpha-hydroxypregnenlone (OHPREG) versus 17alpha-hydroxyprogesterone (OHPROG). Carbon 30-36 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 118-125 29283561-3 2018 However, the subsequent 17,20 carbon-carbon scission reaction displays variable substrate specificity in the numerous CYP17A1 isozymes operating in vertebrates, manifesting as different Kd and kcat values when presented with 17alpha-hydroxypregnenlone (OHPREG) versus 17alpha-hydroxyprogesterone (OHPROG). Carbon 37-43 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 118-125 29441126-13 2018 Overexpression of CTT1 and PRX1 in the recombinant strain S. cerevisiae YRH396 deriving from S. cerevisiae YB-2625 increased cell growth when xylose was used as the sole carbon source, leading to 13.5 and 18.1%, respectively, more xylose consumption. Carbon 170-176 thioredoxin peroxidase PRX1 Saccharomyces cerevisiae S288C 27-31 29208650-9 2018 The various Yrr1 alleles also influenced growth on different carbon sources by altering the function of the mitochondria. Carbon 61-67 Yrr1p Saccharomyces cerevisiae S288C 12-16 29431719-8 2018 Dieldrin and DDx concentrations were highest in the solids contact process, where biomass is accumulated for carbon removal. Carbon 109-115 aldo-keto reductase family 1 member C3 Homo sapiens 13-16 29416560-4 2018 Mig1 orthologs found in all yeast and filamentous fungi are transcriptional regulators that maintain carbon homeostasis by negatively regulating genes of secondary carbon source utilization. Carbon 101-107 transcription factor MIG1 Saccharomyces cerevisiae S288C 0-4 29416560-4 2018 Mig1 orthologs found in all yeast and filamentous fungi are transcriptional regulators that maintain carbon homeostasis by negatively regulating genes of secondary carbon source utilization. Carbon 164-170 transcription factor MIG1 Saccharomyces cerevisiae S288C 0-4 29416560-14 2018 Our findings are particularly important in shedding light on important functions performed by Mig1 in addition to its role as negative regulator of alternate carbon source utilization in filamentous fungi. Carbon 158-164 transcription factor MIG1 Saccharomyces cerevisiae S288C 94-98 29361679-3 2018 Herein, we report the electrochemical detection of CLU for the first time using a screen-printed carbon electrode (SPCE) modified with 1-pyrenebutyric acid N-hydroxysuccinimide ester (Pyr-NHS) and decorated with specific anti-CLU antibody fragments. Carbon 97-103 clusterin Homo sapiens 51-54 29346402-10 2018 These clusters contained putative binding sites for the carbon source responsive transcription factors Mig1 and Adr1. Carbon 56-62 transcription factor MIG1 Saccharomyces cerevisiae S288C 103-107 28738228-4 2018 Glucose dehydrogenase (GDH) was immobilized in the SA-based hydrogel, and the hydrogel was then coated on a glassy carbon electrode (GCE) and used for the biocatalytic oxidation of glucose. Carbon 115-121 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 0-21 28738228-4 2018 Glucose dehydrogenase (GDH) was immobilized in the SA-based hydrogel, and the hydrogel was then coated on a glassy carbon electrode (GCE) and used for the biocatalytic oxidation of glucose. Carbon 115-121 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 23-26 29298419-0 2018 Oxygen-Sensitive Remodeling of Central Carbon Metabolism by Archaic eIF5B. Carbon 39-45 eukaryotic translation initiation factor 5B Homo sapiens 68-73 29298419-5 2018 Global translatome studies revealed central carbon metabolism, cellular hypoxic adaptation, and ATF4-mediated stress response as major eIF5B-dependent pathways. Carbon 44-50 eukaryotic translation initiation factor 5B Homo sapiens 135-140 28804989-5 2018 Here, we use the Ecosystem Demography model (ED2) to predict carbon fluxes of a Puerto Rican tropical forest under realistic climate change scenarios. Carbon 61-67 gap junction protein beta 6 Homo sapiens 45-48 29024190-1 2017 Xyloside analogues with substitution of the endocyclic oxygen atom by sulfur or carbon were investigated as substrates for beta-1,4-galactosyltransferase 7 (beta4GalT7), a key enzyme in the biosynthesis of glycosaminoglycan chains. Carbon 80-86 beta-1,4-galactosyltransferase 7 Homo sapiens 123-155 29024190-1 2017 Xyloside analogues with substitution of the endocyclic oxygen atom by sulfur or carbon were investigated as substrates for beta-1,4-galactosyltransferase 7 (beta4GalT7), a key enzyme in the biosynthesis of glycosaminoglycan chains. Carbon 80-86 beta-1,4-galactosyltransferase 7 Homo sapiens 157-167 33445396-0 2017 Cell Microenvironment pH Sensing in 3D Microgels Using Fluorescent Carbon Dots. Carbon 67-73 phenylalanine hydroxylase Homo sapiens 22-24 33445396-1 2017 We report here a 3D cell culture microgel-based system containing carbon dots capable of sensing the pH changes in the cellular microenvironment. Carbon 66-72 phenylalanine hydroxylase Homo sapiens 101-103 33445396-2 2017 We have utilized a simple droplet-based microfluidics methodology for encapsulating cells and fluorescent pH sensitive carbon dots in polyethylene glycol microgels. Carbon 119-125 phenylalanine hydroxylase Homo sapiens 106-108 33445396-4 2017 The synthesized pH sensitive carbon dots possess green fluorescence emission, which increases as the pH is lowered from neutral to acidic. Carbon 29-35 phenylalanine hydroxylase Homo sapiens 16-18 33445396-4 2017 The synthesized pH sensitive carbon dots possess green fluorescence emission, which increases as the pH is lowered from neutral to acidic. Carbon 29-35 phenylalanine hydroxylase Homo sapiens 101-103 22968412-2 2012 The survival of C-3102 spores in TIM-1 was 99%; 8% of the spores had germinated. Carbon 16-17 Rho guanine nucleotide exchange factor 5 Homo sapiens 33-38 28743028-1 2017 Herein, a sensitive photo-electrochemical sensor based on C3N4 and reduced graphene oxide nanosheets modified glassy carbon electrode (C3N4-RGO/GCE) has been fabricated for the detection of rutin under UV light illumination. Carbon 117-123 glycine decarboxylase Homo sapiens 135-147 22848123-0 2012 The absence of alternative oxidase AOX1A results in altered response of photosynthetic carbon assimilation to increasing CO(2) in Arabidopsis thaliana. Carbon 87-93 alternative oxidase 1A Arabidopsis thaliana 35-40 21693800-0 2011 Effect of hydrophilicity of carbon nanotube arrays on the release rate and activity of recombinant human bone morphogenetic protein-2. Carbon 28-34 bone morphogenetic protein 2 Homo sapiens 105-133 28990751-0 2017 MOF-Derived ZnO Nanoparticles Covered by N-Doped Carbon Layers and Hybridized on Carbon Nanotubes for Lithium-Ion Battery Anodes. Carbon 49-55 lysine acetyltransferase 8 Homo sapiens 0-3 21592767-1 2011 A novel biosensor is developed based on immobilization of proteins on nanoflake-like SnS2 modified glass carbon electrode (GCE). Carbon 105-111 sodium voltage-gated channel alpha subunit 11 Homo sapiens 85-89 22696244-0 2012 Microwave decoration of Pt nanoparticles on entangled 3D carbon nanotube architectures as PEM fuel cell cathode. Carbon 57-63 mucin 1, cell surface associated Homo sapiens 90-93 28990751-0 2017 MOF-Derived ZnO Nanoparticles Covered by N-Doped Carbon Layers and Hybridized on Carbon Nanotubes for Lithium-Ion Battery Anodes. Carbon 81-87 lysine acetyltransferase 8 Homo sapiens 0-3 28738552-1 2017 A modified anaerobic/anoxic/oxic (mA2/O) process based on utilizing the internal carbon source and adding polypropylene carriers was operated for 90d to investigate the nutrients removal performance and bacterial community. Carbon 81-87 G protein-coupled receptor 162 Mus musculus 34-39 21791160-4 2012 A linkage study found that nicotinamide-N-methyltransferase (NNMT), an enzyme involved in one-carbon metabolism, is a determinant of plasma homocysteine levels. Carbon 94-100 nicotinamide N-methyltransferase Homo sapiens 27-59 21791160-4 2012 A linkage study found that nicotinamide-N-methyltransferase (NNMT), an enzyme involved in one-carbon metabolism, is a determinant of plasma homocysteine levels. Carbon 94-100 nicotinamide N-methyltransferase Homo sapiens 61-65 21511809-6 2011 ASP2 encodes for cytosolic aspartate aminotransferase (AAT), a PLP-dependent enzyme that plays a key role in carbon and nitrogen metabolism. Carbon 109-115 aspartate aminotransferase 2 Arabidopsis thaliana 0-4 21511809-6 2011 ASP2 encodes for cytosolic aspartate aminotransferase (AAT), a PLP-dependent enzyme that plays a key role in carbon and nitrogen metabolism. Carbon 109-115 aspartate aminotransferase Arabidopsis thaliana 55-58 21418356-2 2011 In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation. Carbon 74-75 Cytochrome P450 superfamily protein Arabidopsis thaliana 162-170 21418356-2 2011 In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation. Carbon 74-75 Cytochrome P450 superfamily protein Arabidopsis thaliana 171-175 21094255-4 2011 Evidence is presented to show that in the case of CYP17 the attack of Fe(III)-O-O(-) on the target carbon is promoted by cytochrome b(5), which acts as a conformational regulator of CYP17. Carbon 99-105 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 50-55 21094255-4 2011 Evidence is presented to show that in the case of CYP17 the attack of Fe(III)-O-O(-) on the target carbon is promoted by cytochrome b(5), which acts as a conformational regulator of CYP17. Carbon 99-105 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 182-187 28833038-0 2017 LCE: leaf carbon exchange data set for tropical, temperate, and boreal species of North and Central America. Carbon 10-16 ELOVL fatty acid elongase 6 Homo sapiens 0-3 21386033-6 2011 Modification of CER1 expression in transgenic plants specifically affects VLC alkane biosynthesis: waxes of TDNA insertional mutant alleles are devoid of VLC alkanes and derivatives, whereas CER1 overexpression dramatically increases the production of the odd-carbon-numbered alkanes together with a substantial accumulation of iso-branched alkanes. Carbon 260-266 Fatty acid hydroxylase superfamily Arabidopsis thaliana 16-20 22532294-7 2012 Concerted coordination of acetophenone and dual hydrogen-atom transfer from the PNP arm and the coordinated ethanol to, respectively, the carbonyl carbon and oxygen atoms, leads to the dearomatized complex [(iPr-PNP*)Fe(CO)(EtO)(MeCH(OH)Ph)] (32). Carbon 138-144 RUNX1 partner transcriptional co-repressor 1 Homo sapiens 224-227 22719388-1 2012 The title compound, (C(14)H(16)N)[Sn(C(6)H(5))(3)(C(2)O(2))], was synthesised by allowing C(2)O(4)(Bz(2)NH(2))(2) (Bz = benzyl) to react with SnPh(3)Cl. Carbon 21-22 syntaphilin Homo sapiens 142-146 21241060-1 2011 Highly nonlinear pump fluence dependence was observed in the ultrafast one-color pump-probe responses excited by 38 fs pulses resonant with the E(22) transition in a room-temperature solution of (6,5) carbon nanotubes. Carbon 201-207 transcription factor 4 Homo sapiens 144-149 28874504-5 2017 For the first time, we identified the vitamin B12 transporter protein TCN2, which is essential for one-carbon metabolism, as being significantly downregulated. Carbon 103-109 transcobalamin 2 Homo sapiens 70-74 21431140-4 2011 These photochemical products most likely form, after hydrogen bonding between C(24)H(12) and H(2)O, through ionization of the PAH and subsequent reactivity with water upon irradiation. Carbon 78-79 phenylalanine hydroxylase Homo sapiens 126-129 22571318-0 2012 Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP kinase-dependent and -independent mechanisms in mouse RAW264.7 macrophages. Carbon 13-19 prostaglandin-endoperoxide synthase 2 Mus musculus 37-42 29089526-3 2017 Here we present a high resolution organic carbon-CaCO3 MAR and delta13CTOC records for the last 300 ky from the BoB. Carbon 42-48 G protein-coupled receptor 15 Homo sapiens 112-115 22426042-2 2012 We describe that their adjuvant potential increases in direct relationship to the length and hydrophilicity of the C-28 attached sugar chain which contains: arabinose-rhamnose in the CA2, arabinose-rhamnose-xylose in the CA3X; arabinose-rhamnose-apiose in the CA3 and arabinose-rhamnose-apiose-apiose in the CA4 saponin. Carbon 115-116 carbonic anhydrase 4 Mus musculus 308-311 21753961-1 2011 In the title compound, [Cr(C(16)H(16)O(2))(CO)(3)], the Cr(0) atom of the Cr(CO)(3) unit is coordinated to the phenyl ring of the flavan ligand in an eta(6) mode, with a normal arene-to-metal distance. Carbon 24-25 endothelin receptor type A Homo sapiens 150-153 28990033-0 2017 Controlled direct electron transfer kinetics of fructose dehydrogenase at cup-stacked carbon nanofibers. Carbon 86-92 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 48-70 21156972-5 2011 The Mthfd1 gene product, C1-tetrahydrofolate synthase, is a trifunctional enzyme that generates one-carbon substituted tetrahydrofolate cofactors for one-carbon metabolism. Carbon 100-106 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 4-10 21156972-5 2011 The Mthfd1 gene product, C1-tetrahydrofolate synthase, is a trifunctional enzyme that generates one-carbon substituted tetrahydrofolate cofactors for one-carbon metabolism. Carbon 100-106 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 25-53 28990033-2 2017 Here, we immobilized fructose dehydrogenase (FDH) onto the surface of cup-stacked carbon nanofibers (CSCNFs), which provide highly ordered graphene edges with a controlled O/C ratio, and investigated the direct electron communication with FDH. Carbon 82-88 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 21-43 28990033-2 2017 Here, we immobilized fructose dehydrogenase (FDH) onto the surface of cup-stacked carbon nanofibers (CSCNFs), which provide highly ordered graphene edges with a controlled O/C ratio, and investigated the direct electron communication with FDH. Carbon 82-88 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 45-48 20680698-0 2011 PAH desorption from sediments with different contents of organic carbon from wastewater receiving rivers. Carbon 65-71 phenylalanine hydroxylase Homo sapiens 0-3 28990033-2 2017 Here, we immobilized fructose dehydrogenase (FDH) onto the surface of cup-stacked carbon nanofibers (CSCNFs), which provide highly ordered graphene edges with a controlled O/C ratio, and investigated the direct electron communication with FDH. Carbon 82-88 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 239-242 28990033-3 2017 As the O/C ratio decreased at the CSCNF surface, the negative zeta potential was mitigated and the electrochemical communication with FDH was facilitated. Carbon 9-10 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 134-137 29140132-0 2017 Mediation of the single-walled carbon nanotubes induced pulmonary fibrogenic response by osteopontin and TGF-beta1. Carbon 31-37 secreted phosphoprotein 1 Mus musculus 89-100 21205212-2 2011 Zea mays PAO (ZmPAO) oxidizes the carbon on the endo-side of the N5-nitrogen of spermidine (Spd) and spermine (Spm). Carbon 34-40 polyamine oxidase 1 Zea mays 9-12 21205212-2 2011 Zea mays PAO (ZmPAO) oxidizes the carbon on the endo-side of the N5-nitrogen of spermidine (Spd) and spermine (Spm). Carbon 34-40 polyamine oxidase 1 Zea mays 14-19 29140132-0 2017 Mediation of the single-walled carbon nanotubes induced pulmonary fibrogenic response by osteopontin and TGF-beta1. Carbon 31-37 transforming growth factor, beta 1 Mus musculus 105-114 21252703-3 2011 METHODS: In a community-based population of 1014 healthy participants, SBP-C and PP-C were estimated using carotid tonometry, and 24-h systolic (SBP-24 h) and pulse pressure (PP-24 h) were obtained from 24-h ambulatory blood pressure monitoring. Carbon 75-76 selenium binding protein 1 Homo sapiens 71-74 28939642-1 2017 The hepatic lipase (LIPC) locus is a well-established determinant of high-density lipoprotein cholesterol (HDL-C) concentrations, an association that is modified by dietary fat in observational studies. Carbon 23-24 lipase C, hepatic type Homo sapiens 4-18 21288244-2 2011 Here, we aimed to assess the realism of modelled vegetation and carbon storage changes between LGM and the pre-industrial Holocene (PIH). Carbon 64-70 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 132-135 21168968-5 2011 Combustion efficiency (eta(C)), which measures the tendency to convert organic carbon to CO(2), was also determined for all the amines, being eta(CA1)<eta(CA2)<eta(CA3)<eta(CA4)=0.99. Carbon 79-85 endothelin receptor type A Homo sapiens 23-26 28961268-5 2017 HXT2 expression is induced in the mutant regardless of the growth conditions either at high glucose concentration or in the presence of a non-fermentable carbon source such as glycerol. Carbon 154-160 hexose transporter HXT2 Saccharomyces cerevisiae S288C 0-4 21522252-1 2011 The title compound, [RuCl(2)(C(9)H(12))(C(2)H(6)OS)], features a planar [maximum deviation = 0.0075 (17) A] eta(6)-bound mesitylene ligand and a dimethyl sulfoxide ligand coordinated via the S atom. Carbon 23-24 endothelin receptor type A Homo sapiens 108-111 28858489-2 2017 In the last years, some N-heterocyclic carbene (NHC) complexes of high-valent d0 transition-metal halides have been structurally characterized, showing a significant short distance between the carbene carbon and the cis-halide ligands (Clax). Carbon 201-207 C-type lectin domain family 2 member D Homo sapiens 236-240 20299096-9 2011 Expression of Jf-ISG15 was strongly induced by poly-I:C treatment in head-kidney cells, peripheral blood leukocytes (PBLs) and spleen cells, and by HIRRV infection in kidney of juvenile fish suggesting that Jf-ISG15 plays a role in fish antiviral response. Carbon 54-55 ISG15 ubiquitin like modifier Homo sapiens 17-22 21686160-1 2011 D-(+)-Galactose-conjugated single-walled carbon nanotubes (SWCNTs) were synthesized for use as biosensors to detect the cancer marker galectin-3. Carbon 41-47 galectin 3 Homo sapiens 134-144 20932985-6 2011 Both the reduction of JAM-A expression and the induction of secretion of IL-8 and TNF-alpha after treatment with poly(I:C) were modulated by distinct signal transduction pathways via EGFR, PI3K, and p38 MAPK and finally regulated by a TLR3-mediated NF-kappaB pathway. Carbon 120-121 toll like receptor 3 Homo sapiens 235-239 28891976-2 2017 Carbon nanotubes were introduced into a cement paste in the form of an aqueous dispersion in the presence of a surfactant (SDS-sodium dodecyl sulfate), which was sonicated. Carbon 0-6 serine dehydratase Homo sapiens 123-126 20876298-0 2010 Ime1 and Ime2 are required for pseudohyphal growth of Saccharomyces cerevisiae on nonfermentable carbon sources. Carbon 97-103 transcription factor IME1 Saccharomyces cerevisiae S288C 0-4 20876298-5 2010 Two stimulators of meiosis, Ime1 and Ime2, are required for pseudohyphal growth of SK1 cells in the presence of nonfermentable carbon sources. Carbon 127-133 transcription factor IME1 Saccharomyces cerevisiae S288C 28-32 28891976-8 2017 Further research on the carbon nanotube reinforced cement paste, with SDS, may contribute to the development of a modified cement binder for the production of a lightweight or an aerated concrete. Carbon 24-30 serine dehydratase Homo sapiens 70-73 20886873-1 2010 Computational studies have suggested that eta(3)-lithium enolates in which the cation is partially bound to both carbon and oxygen may be important reactive intermediates. Carbon 113-119 endothelin receptor type A Homo sapiens 42-45 28883526-4 2017 Structure-activity studies indicate that the minimal requirements for potent beta-lactam-based TRPM8 blockers are hydrophobic groups (benzyl preferentially or t Bu) on R1, R2, R3 and R5 and a short N-alkyl chain (<=3 carbons). Carbon 220-227 transient receptor potential cation channel subfamily M member 8 Homo sapiens 95-100 28809478-4 2017 p-Phenylene is bound to the ruthenium cation in an eta2 fashion, revealing the shortest ever Ru-C distance in the series of p-benziporphyrin complexes [RuII(p-BzP)(CO)Cl, 2.275(2) A; RuIII(p-BzP)Cl2, 2.324(5) A]. Carbon 96-97 DNA polymerase iota Homo sapiens 51-55 20878799-4 2010 The results suggest that the reaction proceeds through an [LSi{C(Ph)==C(Ph)}SiL] intermediate, which then reacts with another molecule of PhC[triple chemical bond]CPh to form 3. Carbon 63-64 STIL centriolar assembly protein Homo sapiens 76-79 20878799-4 2010 The results suggest that the reaction proceeds through an [LSi{C(Ph)==C(Ph)}SiL] intermediate, which then reacts with another molecule of PhC[triple chemical bond]CPh to form 3. Carbon 70-71 STIL centriolar assembly protein Homo sapiens 76-79 28874822-2 2017 AS1411, a nucleolin aptamer, is wrapped around water-soluble carbon dots and used as a probe for the detection of several types of cancer cells. Carbon 61-67 nucleolin Homo sapiens 10-19 20947737-1 2010 Carbon-linking catalysts get Nobel nod. Carbon 0-6 atrophin 1 Homo sapiens 35-38 28653777-0 2017 Vertical-Aligned Li2 S-Graphene Encapsulated within a Carbon Shell as a Free-Standing Cathode for Lithium-Sulfur Batteries. Carbon 54-60 ATP binding cassette subfamily A member 12 Homo sapiens 17-20 20655192-1 2010 Carbon nanotubes (CNTs) were "dissolved" in mixed solution of cyclodextrin (CD) and cyclodextrin prepolymer (pre-CDP) and were used as modifier to fabricate chemical modified electrode. Carbon 0-6 cut like homeobox 1 Homo sapiens 113-116 28653777-2 2017 In this work, we have developed a double-modification strategy to integrate lithium sulfide (Li2 S) into a conductive composite network consisting of vertical graphene (VG) arrays and an amorphous carbon shell, forming an integrated cathode (VG/Li2 S-C). Carbon 197-203 ATP binding cassette subfamily A member 12 Homo sapiens 93-96 20687575-5 2010 These data show that TIM and BSA exhibit a modest catalytic activity toward deprotonation of the alpha-hydroxy alpha-carbonyl carbon. Carbon 117-123 Rho guanine nucleotide exchange factor 5 Homo sapiens 21-24 28559181-1 2017 The MTHFD1 gene encodes for methylenetetrahydrofolate dehydrogenase 1, an enzyme that has an important role in folate-mediated one-carbon metabolism. Carbon 131-137 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 4-10 20541802-9 2010 Chemically and biochemically the cir-PDL adjacent to bone and cementum was identified by relatively higher carbon and lower calcium including the localization of small leucine rich proteins responsible for maintaining soft-hard tissue cohesion, stiffness and hygroscopic nature of PDL-bone and PDL-cementum attachment sites. Carbon 107-113 programmed cell death 1 Homo sapiens 37-40 28559181-1 2017 The MTHFD1 gene encodes for methylenetetrahydrofolate dehydrogenase 1, an enzyme that has an important role in folate-mediated one-carbon metabolism. Carbon 131-137 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 28-69 28559181-3 2017 Mice homozygous for a loss of Mthfd1 via a gene-trap mutation are not viable, and heterozygotes, though they appear healthy, have metabolic imbalances in the folate- and choline-mediated 1-carbon metabolic pathways. Carbon 189-195 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 30-36 20870960-0 2010 Expression of a low CO2-inducible protein, LCI1, increases inorganic carbon uptake in the green alga Chlamydomonas reinhardtii. Carbon 69-75 uncharacterized protein Chlamydomonas reinhardtii 43-47 28523730-9 2017 By contrast, the use of methanol as a carbon source generated small cells and a shift in carbon metabolism toward the dissimilatory pathway by the upregulation of formaldehyde dehydrogenase gene and the downregulation of those of the central metabolic. Carbon 38-44 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 163-189 20930525-5 2010 These findings provide new insights into the regulation of greening and carbon-nitrogen balance by sugar metabolism through INV-E in plastids. Carbon 72-78 alkaline/neutral invertase Arabidopsis thaliana 124-129 20580059-2 2010 The formation of trihalomethanes (THMs), haloacetic acids (HAAs), and total organic halide (TOX) upon chlorination of untreated water, and after conventional treatment, granular activated carbon treatment, and nanofiltration were quantified using ANNs. Carbon 188-194 thymocyte selection associated high mobility group box Homo sapiens 92-95 22378735-1 2012 BACKGROUND: MTHFD1 encodes C1-tetrahydrofolate synthase, which is a folate-dependent enzyme that catalyzes the formation and interconversion of folate-activated one-carbon groups for nucleotide biosynthesis and cellular methylation. Carbon 165-171 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 12-18 28523730-9 2017 By contrast, the use of methanol as a carbon source generated small cells and a shift in carbon metabolism toward the dissimilatory pathway by the upregulation of formaldehyde dehydrogenase gene and the downregulation of those of the central metabolic. Carbon 89-95 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 163-189 22378735-1 2012 BACKGROUND: MTHFD1 encodes C1-tetrahydrofolate synthase, which is a folate-dependent enzyme that catalyzes the formation and interconversion of folate-activated one-carbon groups for nucleotide biosynthesis and cellular methylation. Carbon 165-171 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 27-55 28773156-1 2017 The conventional gas diffusion layer (GDL) of polymer electrolyte membrane (PEM) fuel cells incorporates a carbon-based substrate, which suffers from electrochemical oxidation as well as mechanical degradation, resulting in reduced durability and performance. Carbon 107-113 mucin 1, cell surface associated Homo sapiens 76-79 22222967-6 2012 In whole-cell patch-clamp recordings, higher alcohols (1-hexanol to 1-octanol) activated hTRPA1 and the potency increased with the carbon chain length. Carbon 131-137 transient receptor potential cation channel subfamily A member 1 Homo sapiens 89-95 21141120-12 2010 The activities of chymosin were not prominent increased when galactose was used as carbon source instead of glucose, which proved that the fermentation of recombinant strain does not need galactose inducing. Carbon 83-89 chymosin Bos taurus 18-26 22222967-11 2012 We conclude that primary and secondary alcohols activate hTRPA1 in a carbon chain length-dependent manner. Carbon 69-75 transient receptor potential cation channel subfamily A member 1 Homo sapiens 57-63 20589285-1 2010 Strong electrochemiluminescence signals caused by the highly effective electron transfer process between SnO nanoparticles-deposited multiwall carbon nanotubes (SnO NPs@MWCNTs) composite and Ru(bpy)(3)(3+) were observed. Carbon 143-149 strawberry notch homolog 1 Homo sapiens 105-108 28544445-4 2017 Due to the intimate electrical and chemical coupling between the oxide nanocrystals and integrated carbon, the dual-phase octahedral CoMn2 O4 /carbon hollow nanofibers exhibit excellent OER activity with overpotentials of 337 mV at current density of 10 mA cm-2 and Tafel slope of 82 mV dec-1 . Carbon 143-149 deleted in esophageal cancer 1 Homo sapiens 287-292 20589285-1 2010 Strong electrochemiluminescence signals caused by the highly effective electron transfer process between SnO nanoparticles-deposited multiwall carbon nanotubes (SnO NPs@MWCNTs) composite and Ru(bpy)(3)(3+) were observed. Carbon 143-149 strawberry notch homolog 1 Homo sapiens 161-164 20586413-6 2010 Formation of enediyne SAMs on a template followed by the processing sequence developed in this work is promising to construct carbon materials with various nanoscopic morphology, such as carbon nanotube, graphene, and giant fullerene. Carbon 126-132 methionine adenosyltransferase 1A Homo sapiens 22-26 20586413-6 2010 Formation of enediyne SAMs on a template followed by the processing sequence developed in this work is promising to construct carbon materials with various nanoscopic morphology, such as carbon nanotube, graphene, and giant fullerene. Carbon 187-193 methionine adenosyltransferase 1A Homo sapiens 22-26 22322243-3 2012 The compound C(dppm)(2), which is composed of a divalent carbon atom and two dppm subunits, represents a new PCP-type pincer ligand with the formally neutral carbon Lewis base of the CDP functionality as the central carbon. Carbon 158-164 cut like homeobox 1 Homo sapiens 183-186 28640203-3 2017 In addition, a reduced activated carbon (GACr) was obtained by heating the GAC at 1173 K, to remove the oxygenated surface groups. Carbon 33-39 ornithine aminotransferase Homo sapiens 41-45 22322243-3 2012 The compound C(dppm)(2), which is composed of a divalent carbon atom and two dppm subunits, represents a new PCP-type pincer ligand with the formally neutral carbon Lewis base of the CDP functionality as the central carbon. Carbon 158-164 cut like homeobox 1 Homo sapiens 183-186 22322243-4 2012 Treatment of [M(Cl)(C(dppm)(2)-kappa3P,C,P)]Cl (M = Pd, Pt) with hydrochloric acid results in protonation at the CDP carbon atom and the formation of the PCP pincer complexes [M(Cl)(CH(dppm)(2)-kappa3P,C,P)]Cl(2) (M = Pd, Pt). Carbon 117-123 cut like homeobox 1 Homo sapiens 113-116 20415663-7 2010 The oxygen consumption and metabolic data strongly suggest that knockdown of PDH kinase 1 in beta-cells permits increased metabolic flux of glucose-derived carbons into the tricarboxylic acid cycle via PDH. Carbon 156-163 pyruvate dehydrogenase kinase 1 Rattus norvegicus 77-89 22365688-6 2012 The glucose biosensor which was constructed by entrapping GDH into chitosan on the nanocomposites modified glassy carbon electrode surface, exhibited good electrocatalytic oxidation toward glucose with a detection limit of 9 muM in the linear range of 0.02-1mM. Carbon 114-120 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 58-61 28640203-7 2017 The highest value was obtained for GACr in a paracetamol solution of 1000 mg L-1 at pH 7, confirming that paracetamol adsorption is favoured on basic activated carbons at pH values near to neutrality. Carbon 160-167 ornithine aminotransferase Homo sapiens 35-39 28587448-0 2017 From Si(II) to Si(IV) and Back: Reversible Intramolecular Carbon-Carbon Bond Activation by an Acyclic Iminosilylene. Carbon 58-64 elongin A Homo sapiens 5-11 22027091-4 2012 An Arabidopsis DNA ligase IV mutant, deficient in non-homologous end-joining repair, showed hyper-sensitivity to both types of carbon-ion irradiation. Carbon 127-133 DNA ligase IV Arabidopsis thaliana 15-28 22242898-5 2012 HepG2 cells were easily immobilized on the arginine-glycine-aspartic acid-serine (RGDS)-multiwalled carbon nanotubes (RGDS-MWCNTs) nanocomposite by the specific combination of RGD domains with integrin receptors on the cell surface. Carbon 100-106 ral guanine nucleotide dissociation stimulator Homo sapiens 118-122 22315427-5 2012 As a regulator of carbon and nucleotide metabolism, AMPK is poised to activate many of the metabolic pathways induced by HCMV infection. Carbon 18-24 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 52-56 21587940-1 2010 The structure of the title compound, C(12)H(9)BrN(4), prepared by the reaction of 2-bromo-1-(6-bromo-3-pyrid-yl)ethanone with 2-amino-3-methyl-pyrazine indicates that the compound with the bromo-pyridyl substituent at position 2 of the imidazopyrazine fused-ring system represents the major product of this reaction. Carbon 37-38 POU class 3 homeobox 4 Homo sapiens 46-51 20418089-5 2010 Upon introduction of carbon nanotubes, the carbon fibers exhibited a significant increase in the specific surface area from <10 to 36.4 m(2)/g (determined by the BET method). Carbon 21-27 delta/notch like EGF repeat containing Homo sapiens 165-168 20418089-5 2010 Upon introduction of carbon nanotubes, the carbon fibers exhibited a significant increase in the specific surface area from <10 to 36.4 m(2)/g (determined by the BET method). Carbon 43-49 delta/notch like EGF repeat containing Homo sapiens 165-168 28587448-0 2017 From Si(II) to Si(IV) and Back: Reversible Intramolecular Carbon-Carbon Bond Activation by an Acyclic Iminosilylene. Carbon 65-71 elongin A Homo sapiens 5-11 28481003-0 2017 MOF-Templated Synthesis of Ultrasmall Photoluminescent Carbon-Nanodot Arrays for Optical Applications. Carbon 55-61 lysine acetyltransferase 8 Homo sapiens 0-3 20479116-5 2010 Polyinosine-polycytidylic acid (poly I:C)-activated CD141+ DCs have a superior capacity to cross-present soluble protein antigen (Ag) to CD8+ cytotoxic T lymphocytes than poly I:C-activated CD1c+ DCs. Carbon 39-40 CD1c molecule Homo sapiens 190-194 28296149-6 2017 However, when aap8 plants transitioned to reproductive phase, carbon fixation and assimilation as well as sucrose partitioning to siliques were strongly decreased. Carbon 62-68 amino acid permease 8 Arabidopsis thaliana 14-18 20560707-2 2010 In particular, a T/C change (rs1801260) at the 3111 position of the circadian locomotor output cycles kaput (CLOCK) gene has been explored in psychiatry disorders. Carbon 19-20 clock circadian regulator Homo sapiens 68-107 20560707-2 2010 In particular, a T/C change (rs1801260) at the 3111 position of the circadian locomotor output cycles kaput (CLOCK) gene has been explored in psychiatry disorders. Carbon 19-20 clock circadian regulator Homo sapiens 109-114 20396930-1 2010 We perform a detailed comparison of fast backbone dynamics probed at amide nitrogen versus carbonyl carbon sites for dematin headpiece C-terminal domain (DHP) and its S74E mutant (DHPS74E). Carbon 91-97 dematin actin binding protein Homo sapiens 117-124 22051630-6 2012 Our results demonstrate that different chloride ion concentrations can influence the speciation in the acidic pH range but at biologically relevant conditions (pH = 7.4, c(Cl(-)) = 0.16 M) and at c(M) = 1 muM [{Ru(eta(6)-p-cym)}(2)(mu(2)-OH)(3)](+) is predominant in the absence of any coordinating ligands. Carbon 39-40 endothelin receptor type A Homo sapiens 214-217 22050840-6 2012 The optimum conditions resulted in activated carbon with a monolayer adsorption capacity of 395.30 mg/g and carbon yield of 73.78%, while the BET surface area and total pore volume were corresponding to 1372 m2/g and 0.76 cm3/g, respectively. Carbon 45-51 delta/notch like EGF repeat containing Homo sapiens 142-145 28340736-0 2017 Highly sensitive electrochemical sensor for chloramphenicol based on MOF derived exfoliated porous carbon. Carbon 99-105 lysine acetyltransferase 8 Homo sapiens 69-72 22114354-5 2012 mio10-mutant yeast cells are affected in growth on nonfermentable carbon sources and exhibit altered mitochondrial morphology. Carbon 66-72 Mic10p Saccharomyces cerevisiae S288C 0-5 22160690-6 2011 This competition creates a translational bottleneck that balances the production of Gal1p and Cln3p and represents a posttranscriptional control mechanism that enhances the cell"s ability to adapt to changes in carbon source. Carbon 211-217 galactokinase Saccharomyces cerevisiae S288C 84-89 21964048-5 2011 The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3. Carbon 19-20 toll like receptor 3 Homo sapiens 27-31 21964048-5 2011 The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3. Carbon 19-20 interferon beta 1 Homo sapiens 138-146 21964048-5 2011 The treatment of EPCs with TLR3 agonist Poly I:C up-regulated the expression of cytokines IL-1beta, IL-6, IL-8, TNF-alpha, IFN-alpha, and IFN-beta, indicating that EPCs expressed functional TLR3. Carbon 19-20 toll like receptor 3 Homo sapiens 190-194 22181894-1 2011 A novel carbon allotrope of C-centered orthorhombic C(8) (Cco-C(8)) is predicted by using a recently developed particle-swarm optimization method on structural search. Carbon 8-14 homeobox C8 Homo sapiens 52-56 22181894-1 2011 A novel carbon allotrope of C-centered orthorhombic C(8) (Cco-C(8)) is predicted by using a recently developed particle-swarm optimization method on structural search. Carbon 8-14 homeobox C8 Homo sapiens 62-66 22181894-2 2011 Cco-C(8) adopts a sp(3) three-dimensional bonding network that can be viewed as interconnected (2,2) carbon nanotubes through 4- and 6-member rings and is energetically more favorable than earlier proposed carbon polymorphs (e.g., M carbon, bct-C(4), W carbon, and chiral C(6)) over a wide range of pressures studied (0-100 GPa). Carbon 101-107 homeobox C8 Homo sapiens 4-8 22181894-2 2011 Cco-C(8) adopts a sp(3) three-dimensional bonding network that can be viewed as interconnected (2,2) carbon nanotubes through 4- and 6-member rings and is energetically more favorable than earlier proposed carbon polymorphs (e.g., M carbon, bct-C(4), W carbon, and chiral C(6)) over a wide range of pressures studied (0-100 GPa). Carbon 206-212 homeobox C8 Homo sapiens 4-8 22181894-2 2011 Cco-C(8) adopts a sp(3) three-dimensional bonding network that can be viewed as interconnected (2,2) carbon nanotubes through 4- and 6-member rings and is energetically more favorable than earlier proposed carbon polymorphs (e.g., M carbon, bct-C(4), W carbon, and chiral C(6)) over a wide range of pressures studied (0-100 GPa). Carbon 206-212 homeobox C8 Homo sapiens 4-8 22181894-2 2011 Cco-C(8) adopts a sp(3) three-dimensional bonding network that can be viewed as interconnected (2,2) carbon nanotubes through 4- and 6-member rings and is energetically more favorable than earlier proposed carbon polymorphs (e.g., M carbon, bct-C(4), W carbon, and chiral C(6)) over a wide range of pressures studied (0-100 GPa). Carbon 206-212 homeobox C8 Homo sapiens 4-8 22181894-3 2011 The simulated x-ray diffraction pattern, density, and bulk modulus of Cco-C(8) are in good accordance with the experimental data on structurally undetermined superhard carbon recovered from cold compression of carbon nanotube bundles. Carbon 168-174 homeobox C8 Homo sapiens 74-78 21993223-2 2011 Single-walled carbon nanotubes were functionalized with the F3 peptide using a polyethylene glycol linker to target nucleolin, a protein found on the surface of endothelial cells in the vasculature of solid tumors. Carbon 14-20 nucleolin Homo sapiens 116-125 21922581-0 2011 Palladium-catalyzed C-H bond functionalization of a metal-organic framework (MOF): mild, selective, and efficient. Carbon 20-21 lysine acetyltransferase 8 Homo sapiens 52-82 21962685-2 2011 The carbon ink electrode of DEP chip is modified first by deposition of polypyrrole-pyrole-2-carboxylic acid copolymer and thence hCG antibody immobilization via the COOH groups of pyrrole-2-carboxylic acid, which can serve as a linker for covalent biomolecular immobilization. Carbon 4-10 glycoprotein hormones, alpha polypeptide Homo sapiens 130-133 21624033-4 2011 The present study examines the effect of the introduction of the ZmDof1 gene on carbon and nitrogen assimilation in rice. Carbon 80-86 DNA-binding protein MNB1 Zea mays 65-71 21624033-6 2011 Transgenic rice expressing ZmDof1 and grown in the presence of 360 mum (nitrogen-sufficient) or 90 mum (nitrogen-deficient) of nitrogen concentrations showed modulation of metabolite content and gene expression associated with the anaplerotic pathway for the TCA cycle, suggesting an increased carbon flow towards nitrogen assimilation. Carbon 294-300 DNA-binding protein MNB1 Zea mays 27-33 21624033-7 2011 Furthermore, increases in carbon and nitrogen amounts per seedling were found in Dof1 rice grown under nitrogen-deficient conditions. Carbon 26-32 DNA-binding protein MNB1 Zea mays 81-85 21624033-10 2011 Taken these together, the present study displayed that ZmDof1 expression in rice could induce gene expressions such as PEPC genes, modulate carbon and nitrogen metabolites, increase nitrogen assimilation and enhance growth under low-nitrogen conditions. Carbon 140-146 DNA-binding protein MNB1 Zea mays 55-61 21826370-4 2011 The crystal structure of 1 has been solved to show the coordination of nickel to the C-C bond of C(70) at the 6-6 ring junction of eta(2)-type to form Ni-C(C(70)) bonds of 1.929-1.941(2) A length, the shortest M-C bonds among those known for eta(2)-complexes of fullerenes C(60) and C(70). Carbon 85-86 DNA polymerase iota Homo sapiens 131-136 21826370-4 2011 The crystal structure of 1 has been solved to show the coordination of nickel to the C-C bond of C(70) at the 6-6 ring junction of eta(2)-type to form Ni-C(C(70)) bonds of 1.929-1.941(2) A length, the shortest M-C bonds among those known for eta(2)-complexes of fullerenes C(60) and C(70). Carbon 85-86 DNA polymerase iota Homo sapiens 242-247 21826370-4 2011 The crystal structure of 1 has been solved to show the coordination of nickel to the C-C bond of C(70) at the 6-6 ring junction of eta(2)-type to form Ni-C(C(70)) bonds of 1.929-1.941(2) A length, the shortest M-C bonds among those known for eta(2)-complexes of fullerenes C(60) and C(70). Carbon 87-88 DNA polymerase iota Homo sapiens 131-136 21826370-4 2011 The crystal structure of 1 has been solved to show the coordination of nickel to the C-C bond of C(70) at the 6-6 ring junction of eta(2)-type to form Ni-C(C(70)) bonds of 1.929-1.941(2) A length, the shortest M-C bonds among those known for eta(2)-complexes of fullerenes C(60) and C(70). Carbon 87-88 DNA polymerase iota Homo sapiens 131-136 21826370-4 2011 The crystal structure of 1 has been solved to show the coordination of nickel to the C-C bond of C(70) at the 6-6 ring junction of eta(2)-type to form Ni-C(C(70)) bonds of 1.929-1.941(2) A length, the shortest M-C bonds among those known for eta(2)-complexes of fullerenes C(60) and C(70). Carbon 87-88 DNA polymerase iota Homo sapiens 131-136 21826370-4 2011 The crystal structure of 1 has been solved to show the coordination of nickel to the C-C bond of C(70) at the 6-6 ring junction of eta(2)-type to form Ni-C(C(70)) bonds of 1.929-1.941(2) A length, the shortest M-C bonds among those known for eta(2)-complexes of fullerenes C(60) and C(70). Carbon 87-88 DNA polymerase iota Homo sapiens 131-136 21477884-5 2011 AtDSEL-overexpressing transgenic Arabidopsis plants (35S:AtDSEL) were defective in post-germinative seedling growth in medium without an exogenous carbon source. Carbon 147-153 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 0-7 21477884-5 2011 AtDSEL-overexpressing transgenic Arabidopsis plants (35S:AtDSEL) were defective in post-germinative seedling growth in medium without an exogenous carbon source. Carbon 147-153 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 0-6 21608125-2 2011 For this purpose, an anti-MUC1 antibody (Ab) is linked to both multi-walled (MWCNTs) and double-walled carbon nanotubes (DWCNTs) using different synthetic strategies. Carbon 103-109 mucin 1, cell surface associated Homo sapiens 26-30 21557725-0 2011 Evidence that ACN1 (acetate non-utilizing 1) prevents carbon leakage from peroxisomes during lipid mobilization in Arabidopsis seedlings. Carbon 54-60 acyl-activating enzyme 7 Arabidopsis thaliana 14-18 21557725-0 2011 Evidence that ACN1 (acetate non-utilizing 1) prevents carbon leakage from peroxisomes during lipid mobilization in Arabidopsis seedlings. Carbon 54-60 acyl-activating enzyme 7 Arabidopsis thaliana 20-43 21557725-3 2011 However, the lack of acn1-2 led to a decrease of nearly 50% in (13)C-labelling of glutamine, a major carbon sink in seedlings, and large decreases in primary metabolite levels. Carbon 101-107 acyl-activating enzyme 7 Arabidopsis thaliana 21-27 21557725-10 2011 We discuss the possibility that ACN1 safeguards against the loss of carbon as acetate from peroxisomes during lipid mobilization. Carbon 68-74 acyl-activating enzyme 7 Arabidopsis thaliana 32-36 21970174-2 2011 The first objective of this study was to investigate the physical and chemical properties (BET surface area, ash and elemental content, surface functional groups by Boehm titration and weight loss by thermogravimetric analysis) of the sludge-based activated carbon (SBAC) so as to give a basic understanding of its structure and to compare to those of two commercial activated carbons, PICA S23 and F22. Carbon 258-264 delta/notch like EGF repeat containing Homo sapiens 91-94 22053698-0 2011 Modulatory effect of plasma folate and polymorphisms in one-carbon metabolism on catecholamine methyltransferase (COMT) H108L associated oxidative DNA damage and breast cancer risk. Carbon 60-66 catechol-O-methyltransferase Homo sapiens 114-118 22053698-1 2011 The present study was aimed to investigate the modulatory role of plasma folate and eight putatively functional polymorphisms of one-carbon metabolism on catecholamine methyltransferase (COMT)-mediated oxidative DNA damage and breast cancer risk. Carbon 133-139 catechol-O-methyltransferase Homo sapiens 187-191 22053698-9 2011 To conclude, the current study provides substantial evidence for a cross talk between one-carbon metabolism and COMT catalysis that might influence oxidative DNA damage and breast cancer risk. Carbon 90-96 catechol-O-methyltransferase Homo sapiens 112-116 21501262-10 2011 Finally, growth abnormalities of gabp mutants under limited carbon availability on artificial media, and in soil under low light intensity, combined with their metabolite profiles, suggest an important role for AtGABP in primary carbon metabolism and plant growth. Carbon 60-66 bidirectional amino acid transporter 1 Arabidopsis thaliana 33-37 21501262-10 2011 Finally, growth abnormalities of gabp mutants under limited carbon availability on artificial media, and in soil under low light intensity, combined with their metabolite profiles, suggest an important role for AtGABP in primary carbon metabolism and plant growth. Carbon 229-235 bidirectional amino acid transporter 1 Arabidopsis thaliana 33-37 21501262-10 2011 Finally, growth abnormalities of gabp mutants under limited carbon availability on artificial media, and in soil under low light intensity, combined with their metabolite profiles, suggest an important role for AtGABP in primary carbon metabolism and plant growth. Carbon 229-235 bidirectional amino acid transporter 1 Arabidopsis thaliana 211-217 21501262-11 2011 Thus, AtGABP-mediated transport of GABA from the cytosol into mitochondria is important to ensure proper GABA-mediated respiration and carbon metabolism. Carbon 135-141 bidirectional amino acid transporter 1 Arabidopsis thaliana 6-12 21682329-0 2011 Single-walled carbon nanotubes deliver peptide antigen into dendritic cells and enhance IgG responses to tumor-associated antigens. Carbon 14-20 immunoglobulin heavy chain (V7183 family) Mus musculus 88-91 21507984-5 2011 We also found that RV and poly(I:C) each stimulated Rac1 activation, reactive oxygen species (ROS) generation, and Rac1-dependent NADPH oxidase 1 (NOX1) activity. Carbon 33-34 NADPH oxidase 1 Homo sapiens 130-145 21507984-5 2011 We also found that RV and poly(I:C) each stimulated Rac1 activation, reactive oxygen species (ROS) generation, and Rac1-dependent NADPH oxidase 1 (NOX1) activity. Carbon 33-34 NADPH oxidase 1 Homo sapiens 147-151 21542642-5 2011 The SnO(2) nanowires coated with carbon, aluminum, or copper can be charged about 10 times faster than the noncoated ones. Carbon 33-39 strawberry notch homolog 1 Homo sapiens 4-7 21332506-10 2011 Central clock functions that depend on CCA1/LHY are required to set an appropriate rate of starch degradation and maintain a supply of carbon to support growth through to dawn, whereas ELF3 acts to decrease growth in the light period and promote growth in the night. Carbon 135-141 circadian clock associated 1 Arabidopsis thaliana 39-43 20074856-0 2010 BET surface areas of activated carbons. Carbon 31-38 delta/notch like EGF repeat containing Homo sapiens 0-3 20335551-1 2010 BACKGROUND: The S-adenosylmethionine synthetase type 1 (MAT1A) gene encodes a key enzyme in one-carbon nutrient metabolism. Carbon 96-102 methionine adenosyltransferase 1A Homo sapiens 16-61 20384297-6 2010 The hybrid deposited on the glassy carbon (GC) electrode is demonstrated to be a good bioelectrocatalyst for the reduction of oxygen with inherent enzyme activity, accepted stability, high half-wave potential (ca.670 mV vs NHE), and unimpeded electrical communication to the copper redox sites of laccase. Carbon 35-41 solute carrier family 9 member C1 Homo sapiens 223-226 20089415-4 2010 In order to demonstrate the intracellular pathways involved in poly(I:C)-induced BLyS-expression, we used specific inhibitors of phosphatidylinositol 3-kinase (PI3-kinase), spleen tyrosine kinase (Syk), p38 mitogen-activated protein kinase (p38 MAPK), c-Jun N-terminal kinase (JNK), and extracellular-signal related kinase (ERK)-signaling in these events. Carbon 70-71 TNF superfamily member 13b Homo sapiens 81-85 20202847-3 2010 PTS(Ntr) regulates diverse processes implicated in metabolism of nitrogen and carbon, and is essential for virulence in some bacteria. Carbon 78-84 neurotensin receptor 1 Homo sapiens 0-8 20004569-3 2010 BSG carbons presented BET surface areas between 33 and 692 m(2)/g, and micro- and mesopores with volumes between 0.058 and 0.453 cm(3)/g. Carbon 4-11 delta/notch like EGF repeat containing Homo sapiens 22-25 20112272-1 2010 Compound-specific stable carbon isotope analysis by gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS) is an important method for the determination of the (13)C/(12)C ratios of biomolecules such as steroids, for a wide range of applications. Carbon 25-31 guanylate cyclase 2C Homo sapiens 115-119 20336010-4 2010 In addition an unprecedented reactivity of DCP as a very reactive heterocyclic electrophile at the C-4 carbon was also evidenced: by changing the experimental conditions, cyanopyrrolyl- and cyanoindolyl-pyridazines were obtained through reactions of pyrrole and indole systems as carbon nucleophiles in formal SNAr2 processes where a CN group of DCP acts as leaving group. Carbon 103-109 small NF90 (ILF3) associated RNA H Homo sapiens 310-315 20155902-5 2010 The CANCA experiment correlates alpha carbons with the sequentially adjacent and succeeding nitrogen and alpha carbons. Carbon 38-45 proteinase 3 Homo sapiens 4-9 20155902-5 2010 The CANCA experiment correlates alpha carbons with the sequentially adjacent and succeeding nitrogen and alpha carbons. Carbon 111-118 proteinase 3 Homo sapiens 4-9 20162176-0 2010 Suppression of PF6- intercalation into graphite by small amounts of ethylene carbonate in activated carbon/graphite capacitors. Carbon 77-83 sperm associated antigen 17 Homo sapiens 15-18 20228895-3 2010 We report here the synthesis and validation of azi-isoflurane, a compound constructed by adding a diazirinyl moiety to the methyl carbon of the commonly used general anesthetic isoflurane. Carbon 130-136 ornithine decarboxylase antizyme 1 Homo sapiens 47-50 20055419-2 2010 The biosensor is fabricated using tyrosinase immobilized in a biocompatible matrix consisting of a biopolymer, chitosan and ceria-based metal oxides, deposited onto the surface of a carbon fiber microelectrode with a diameter of approximately 100 microm. Carbon 182-188 tyrosinase Rattus norvegicus 34-44 19955262-3 2010 The carbon catabolite repressor 4-CCR4 associated factor1 (CCR4-CAF1) complex is the major enzyme complex that catalyzes mRNA deadenylation and is conserved among eukaryotes. Carbon 4-10 CRINKLY4 related 4 Arabidopsis thaliana 34-38 19955262-3 2010 The carbon catabolite repressor 4-CCR4 associated factor1 (CCR4-CAF1) complex is the major enzyme complex that catalyzes mRNA deadenylation and is conserved among eukaryotes. Carbon 4-10 CRINKLY4 related 4 Arabidopsis thaliana 59-63 19955262-3 2010 The carbon catabolite repressor 4-CCR4 associated factor1 (CCR4-CAF1) complex is the major enzyme complex that catalyzes mRNA deadenylation and is conserved among eukaryotes. Carbon 4-10 RNA-binding CRS1 / YhbY (CRM) domain-containing protein Arabidopsis thaliana 64-68 20672094-0 2010 Carbon-Coated SnO(2) Nanorod Array for Lithium-Ion Battery Anode Material. Carbon 0-6 strawberry notch homolog 1 Homo sapiens 14-17 20672094-1 2010 Carbon-coated SnO(2) nanorod array directly grown on the substrate has been prepared by a two-step hydrothermal method for anode material of lithium-ion batteries (LIBs). Carbon 0-6 strawberry notch homolog 1 Homo sapiens 14-17 20023935-1 2010 Using two different reaction procedures, a Ru(II) complex has been isolated that contains an ortho-xylylene-linked bis(NHC)cyclophane (NHC = N-heterocyclic carbene) that binds to the Ru centre through two carbene carbons and one of the arene rings in an eta(6)-mode. Carbon 213-220 endothelin receptor type A Homo sapiens 254-257 19799901-12 2010 RNA interference indicates that the polyI:C-induced PGLYRP-2 was dramatically blocked in the cells transfected with siRNA-TRIF but neither siRNA-MyD88 nor the negative control siRNA-F. Carbon 42-43 MYD88 innate immune signal transduction adaptor Homo sapiens 145-150 19966463-2 2009 An ADH3-disrupted mutant exhibited growth retardation on non-fermentable carbon sources, except for ethanol, and this was suppressed by supplementation with antioxidants. Carbon 73-79 alcohol dehydrogenase ADH3 Saccharomyces cerevisiae S288C 3-7 19702666-0 2009 CNI1/ATL31, a RING-type ubiquitin ligase that functions in the carbon/nitrogen response for growth phase transition in Arabidopsis seedlings. Carbon 63-69 carbon/nitrogen insensitive 1 Arabidopsis thaliana 0-4 19702666-0 2009 CNI1/ATL31, a RING-type ubiquitin ligase that functions in the carbon/nitrogen response for growth phase transition in Arabidopsis seedlings. Carbon 63-69 carbon/nitrogen insensitive 1 Arabidopsis thaliana 5-10 19702666-4 2009 One line, cni1-D (carbon/nitrogen insensitive 1-dominant), was shown to have a suppressed sensitivity to C/N conditions at both the physiological and molecular level. Carbon 18-24 carbon/nitrogen insensitive 1 Arabidopsis thaliana 10-14 19702666-4 2009 One line, cni1-D (carbon/nitrogen insensitive 1-dominant), was shown to have a suppressed sensitivity to C/N conditions at both the physiological and molecular level. Carbon 105-106 carbon/nitrogen insensitive 1 Arabidopsis thaliana 10-14 19908567-2 2009 Fourier Transform Infrared Spectra (FTIR) exhibited that Carbon nanotubes (CNT"s) were linked with PES. Carbon 57-63 pescadillo ribosomal biogenesis factor 1 Homo sapiens 99-102 19874630-12 2009 In contrast, SGA1 expression was independent of the carbon source and increased by 3-fold in stationary phase. Carbon 52-58 glucan 1,4-alpha-glucosidase Saccharomyces cerevisiae S288C 13-17 19894971-1 2009 We employ all-electron ab initio time-dependent density functional theory based method to calculate the long-range dipole-dipole dispersion coefficient, namely, the van der Waals (vdW) coefficient (C(6)) between fullerenes and finite-length carbon nanotubes as well as between these structures and different small molecules. Carbon 241-247 complement C6 Homo sapiens 198-202 19894971-5 2009 It is observed from our calculations that the C(6) coefficients of the carbon nanotubes increase nonlinearly with length, which implies a much stronger vdW interaction between the longer carbon nanostructures compared with the shorter ones. Carbon 71-77 complement C6 Homo sapiens 46-50 19894971-5 2009 It is observed from our calculations that the C(6) coefficients of the carbon nanotubes increase nonlinearly with length, which implies a much stronger vdW interaction between the longer carbon nanostructures compared with the shorter ones. Carbon 187-193 complement C6 Homo sapiens 46-50 19894971-6 2009 Additionally, it is found that the values of C(6) and polarizability are about 40%-50% lower for the carbon cages when compared with the results corresponding to the quasi-one-dimensional nanotubes with equivalent number of atoms. Carbon 101-107 complement C6 Homo sapiens 45-49 19894971-7 2009 From our calculations of the vdW coefficients between the small molecules and the carbon nanostructures, it is observed that for H(2), the C(6) value is much larger compared with that of He. Carbon 82-88 complement C6 Homo sapiens 139-143 19894971-10 2009 Carbon tetrachloride as well as chlorine molecule show very high C(6) values with themselves as well as with the carbon nanostructures. Carbon 113-119 complement C6 Homo sapiens 65-69 19772341-1 2009 Irradiation of silicon-bridged [1]ferrocenophane [Fe(eta-C(5)H(4))(2)SiMe(2)] (1) in the presence of substitutionally labile Lewis bases such as 4,4"-dimethyl-2,2"-bipyridine (Me(2)bpy) initiates ring-opening polymerization and oligomerization via cleavage of an iron-cyclopentadienyl bond. Carbon 57-58 endothelin receptor type A Homo sapiens 53-56 19835593-0 2009 Ultrafine carbon particles down-regulate CYP1B1 expression in human monocytes. Carbon 10-16 cytochrome P450 family 1 subfamily B member 1 Homo sapiens 41-47 19735871-10 2009 mRNA expression of ANLN, a homologue of anillin, was suppressed to 60% levels of basal expression in carbon beam-irradiated A549 cells after 12 h. CONCLUSION: Carbon beam effectively suppresses the metastatic potential of A549 and EBC-1 cells. Carbon 101-107 anillin, actin binding protein Homo sapiens 19-23 19735871-10 2009 mRNA expression of ANLN, a homologue of anillin, was suppressed to 60% levels of basal expression in carbon beam-irradiated A549 cells after 12 h. CONCLUSION: Carbon beam effectively suppresses the metastatic potential of A549 and EBC-1 cells. Carbon 159-165 anillin, actin binding protein Homo sapiens 19-23 19735871-11 2009 Carbon beam also has different effects on gene expressions, and downregulation of ANLN was induced only by carbon beam irradiation. Carbon 0-6 anillin, actin binding protein Homo sapiens 82-86 19735871-11 2009 Carbon beam also has different effects on gene expressions, and downregulation of ANLN was induced only by carbon beam irradiation. Carbon 107-113 anillin, actin binding protein Homo sapiens 82-86 21430249-3 2011 Pyridoxal 5"-phosphate (PLP) serves as a coenzyme in enzymes involved in transsulfuration as well as for primary acquisition of 1-carbon units used for remethylation and other phases of 1-carbon metabolism. Carbon 130-136 pyridoxal phosphatase Homo sapiens 24-27 21430249-3 2011 Pyridoxal 5"-phosphate (PLP) serves as a coenzyme in enzymes involved in transsulfuration as well as for primary acquisition of 1-carbon units used for remethylation and other phases of 1-carbon metabolism. Carbon 188-194 pyridoxal phosphatase Homo sapiens 24-27 21094255-3 2011 Certain members of the P-450 family, including CYP17 and CYP19, catalyze, at the same active site, not only the hydroxylation process but also an acyl-carbon bond cleavage reaction which has been interpreted to involve the nucleophilic attack of the ferric-peroxyanion, Fe(III)-O-O(-), on the acyl carbon to furnish a tetrahedral intermediate which fragments, leading to acyl-carbon cleavage. Carbon 151-157 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 47-52 21094255-3 2011 Certain members of the P-450 family, including CYP17 and CYP19, catalyze, at the same active site, not only the hydroxylation process but also an acyl-carbon bond cleavage reaction which has been interpreted to involve the nucleophilic attack of the ferric-peroxyanion, Fe(III)-O-O(-), on the acyl carbon to furnish a tetrahedral intermediate which fragments, leading to acyl-carbon cleavage. Carbon 298-304 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 47-52 21094255-3 2011 Certain members of the P-450 family, including CYP17 and CYP19, catalyze, at the same active site, not only the hydroxylation process but also an acyl-carbon bond cleavage reaction which has been interpreted to involve the nucleophilic attack of the ferric-peroxyanion, Fe(III)-O-O(-), on the acyl carbon to furnish a tetrahedral intermediate which fragments, leading to acyl-carbon cleavage. Carbon 298-304 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 47-52 19756840-2 2009 ATP-binding cassette (ABC) protein systems have been characterized to play important roles in various physiological functions, including carbon fixation, phosphate assimilation, and vitamin B(12) metabolism. Carbon 137-143 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-20 28235739-3 2017 High molecular weight dissolved organic matter (HMW-DOM) recovered by ultrafiltration showed a dissolved organic carbon concentration (HMW-DOC) of about 18-83% of the total dissolved organic carbon measured in Antarctic snow. Carbon 113-119 cilia and flagella associated protein 97 Homo sapiens 48-51 19756840-2 2009 ATP-binding cassette (ABC) protein systems have been characterized to play important roles in various physiological functions, including carbon fixation, phosphate assimilation, and vitamin B(12) metabolism. Carbon 137-143 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 22-25 19663434-3 2009 The correlations obtained for PF2/6 indicate that the (13)C chemical shifts of the aromatic carbons close to the intermonomer connection (C1, C2, and C3) have minimum values at planar conformations (0 degrees and 180 degrees ) and maximum values at 90 degrees conformations. Carbon 92-99 sperm associated antigen 17 Homo sapiens 30-35 21350780-4 2011 The "ArS(+)" pool rapidly reacted with thioacetals to give the corresponding alkoxycarbenium ion pools, which reacted with various carbon nucleophiles (indirect cation pool method). Carbon 131-137 RIEG2 Homo sapiens 5-8 21350780-6 2011 In addition to such stoichiometric reactions, a catalytic amount of "ArS(+)" serves as an initiator and a chain carrier of some cationic chain reactions involving intramolecular carbon-carbon bond formation. Carbon 178-184 RIEG2 Homo sapiens 69-72 21350780-6 2011 In addition to such stoichiometric reactions, a catalytic amount of "ArS(+)" serves as an initiator and a chain carrier of some cationic chain reactions involving intramolecular carbon-carbon bond formation. Carbon 185-191 RIEG2 Homo sapiens 69-72 19663434-6 2009 Considering the aromatic carbons of F8BT, the behavior of C2, C4, C5, and C6 is similar to that found for the PF2/6 carbons. Carbon 116-123 sperm associated antigen 17 Homo sapiens 110-115 28235739-3 2017 High molecular weight dissolved organic matter (HMW-DOM) recovered by ultrafiltration showed a dissolved organic carbon concentration (HMW-DOC) of about 18-83% of the total dissolved organic carbon measured in Antarctic snow. Carbon 113-119 cilia and flagella associated protein 97 Homo sapiens 135-138 19487251-9 2009 In summary, the results indicate that oxidation of the third carbon of the cholestane ring is the preferred position of oxidation by P450 enzymes for lithocholic acid biotransformation in humans and suggest that formation of lithocholic acid metabolites leads to enhanced hepatic detoxification and elimination. Carbon 61-67 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 133-137 21366322-6 2011 The computed kinetic isotope effects (KIE) on the carboxylate C-13 are consistent with that observed on decarboxylation reactions of other PLP-dependent enzymes, whereas the KIEs on the alpha carbon and secondary proton, which can easily be validated experimentally, may be used as a possible identification for the active form of the PLP tautomer in the active site of DDC. Carbon 192-198 pyridoxal phosphatase Homo sapiens 139-142 28235739-3 2017 High molecular weight dissolved organic matter (HMW-DOM) recovered by ultrafiltration showed a dissolved organic carbon concentration (HMW-DOC) of about 18-83% of the total dissolved organic carbon measured in Antarctic snow. Carbon 191-197 cilia and flagella associated protein 97 Homo sapiens 48-51 28088119-1 2017 This study reports the enhanced catalytic ability of metal ions-doped CoS and CoS/carbon allotrope counter electrodes (CEs) (synthesized using a successive ionic layer adsorption and reaction (SILAR) method) to improve the power conversion efficiency (eta) in quantum dot-sensitized solar cells (QDSSCs). Carbon 82-88 endothelin receptor type A Homo sapiens 54-57 19286283-4 2009 Interestingly, the most ERbeta-selective molecules were those bearing non-polar substituents on one of the internal carbon atoms. Carbon 116-122 estrogen receptor 2 Homo sapiens 24-30 28371370-3 2017 A rational nanostructure of hollow carbon nanoboxes filled with birnessite-type manganese oxide nanosheets (MnO2 @HCB) as a new class of molecularly-designed physical and chemical trap for lithium polysulfides (Li2 Sx (x = 4-8)) is reported. Carbon 35-41 ATP binding cassette subfamily A member 12 Homo sapiens 211-214 19561129-0 2009 Metabolic flux analysis of Escherichia coli creB and arcA mutants reveals shared control of carbon catabolism under microaerobic growth conditions. Carbon 92-98 arginine deiminase Escherichia coli 53-57 20920462-3 2011 Plant P450s catalyze a wide variety of monooxygenation/hydroxylation reactions in secondary metabolism, and some of them are involved in unusual reactions such as methylenedioxy-bridge formation, phenol coupling reactions, oxidative rearrangement of carbon skeletons, and oxidative C-C bond cleavage. Carbon 250-256 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 6-11 21162540-5 2011 On the basis of DFT calculations it has been suggested that the conformations most suitable for C-S bond cleavage in 1(+ )-4(+ ) and 7(+ ) are characterized by having the C-S bond almost collinear with the pi system of the cumyl ring and by a significant charge and spin delocalization from the ArS ring to the cumyl ring. Carbon 96-97 RIEG2 Homo sapiens 295-298 28508041-10 2017 Consequently, we report an increased accumulation of carbon-centered radicals in cells lacking TDP1, using electron spin resonance spectroscopy. Carbon 53-59 tyrosyl-DNA phosphodiesterase 1 Mus musculus 95-99 19610658-2 2009 The complexes [(eta(6)-C(10)H(14))RuCl(L)] (L = ndpm and cydpm) reacted with NaN(3) and NH(4)SCN to afford neutral mononuclear complexes [(eta(6)-C(10)H(14))Ru(N(3))(L)] and [(eta(6)-C(10)H(14))Ru(SCN)(L)]. Carbon 21-24 endothelin receptor type A Homo sapiens 16-19 19610658-2 2009 The complexes [(eta(6)-C(10)H(14))RuCl(L)] (L = ndpm and cydpm) reacted with NaN(3) and NH(4)SCN to afford neutral mononuclear complexes [(eta(6)-C(10)H(14))Ru(N(3))(L)] and [(eta(6)-C(10)H(14))Ru(SCN)(L)]. Carbon 144-147 endothelin receptor type A Homo sapiens 16-19 19610658-2 2009 The complexes [(eta(6)-C(10)H(14))RuCl(L)] (L = ndpm and cydpm) reacted with NaN(3) and NH(4)SCN to afford neutral mononuclear complexes [(eta(6)-C(10)H(14))Ru(N(3))(L)] and [(eta(6)-C(10)H(14))Ru(SCN)(L)]. Carbon 144-147 endothelin receptor type A Homo sapiens 16-19 21149657-1 2011 PURPOSE: A phase I/II trial was performed to evaluate the safety and immunogenicity of a novel vaccination with alpha-type 1 polarized dendritic cells (alphaDC1) loaded with synthetic peptides for glioma-associated antigen (GAA) epitopes and administration of polyinosinic-polycytidylic acid [poly(I:C)] stabilized by lysine and carboxymethylcellulose (poly-ICLC) in HLA-A2(+) patients with recurrent malignant gliomas. Carbon 299-301 alpha glucosidase Homo sapiens 197-228 28335594-3 2017 The carbon cage in C84(NC2)Cl30 contains 14 pentagons, 12 of which form two pairs of fused pentagons and two groups of quaternary sequentially fused pentagons, which have never been observed in reported carbon cages. Carbon 4-10 down-regulator of transcription 1 Homo sapiens 23-26 20884204-4 2011 However, highest COD removal was 36.2% in medium containing fructose as the carbon source and electron donor. Carbon 76-82 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 17-20 19425817-8 2009 The oxygen-to-carbon atomic ratio decreased from 0.29, 0.12, and 0.07 for the original lignite (XF0), fusinite (HZ0), and lopinite (LP0) samples, respectively, to 0.07, 0.06, and 0.04 for XF7, HZ7, and LP7, respectively, that underwent the highest temperature treatment. Carbon 14-20 ribosomal protein lateral stalk subunit P0 Homo sapiens 132-135 18682255-8 2009 Smaller effects were also seen for one-carbon metabolism genes choline dehydrogenase (CHDH) (rs9001, rs7626693) and 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) (rs1801394) and genes involved in reduction reactions, glutaredoxin (GLRX) (rs3822751) and peroxiredoxin 2 (PRDX2) (rs10427027, rs12151144). Carbon 39-45 glutaredoxin Homo sapiens 244-256 18682255-8 2009 Smaller effects were also seen for one-carbon metabolism genes choline dehydrogenase (CHDH) (rs9001, rs7626693) and 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) (rs1801394) and genes involved in reduction reactions, glutaredoxin (GLRX) (rs3822751) and peroxiredoxin 2 (PRDX2) (rs10427027, rs12151144). Carbon 39-45 glutaredoxin Homo sapiens 258-262 21686160-0 2011 D-(+)-galactose-conjugated single-walled carbon nanotubes as new chemical probes for electrochemical biosensors for the cancer marker galectin-3. Carbon 41-47 galectin 3 Homo sapiens 134-144 28335594-3 2017 The carbon cage in C84(NC2)Cl30 contains 14 pentagons, 12 of which form two pairs of fused pentagons and two groups of quaternary sequentially fused pentagons, which have never been observed in reported carbon cages. Carbon 203-209 down-regulator of transcription 1 Homo sapiens 23-26 28111287-0 2017 Arabidopsis CBL-Interacting Protein Kinases Regulate Carbon/Nitrogen-Nutrient Response by Phosphorylating Ubiquitin Ligase ATL31. Carbon 53-59 carbon/nitrogen insensitive 1 Arabidopsis thaliana 123-128 20952484-2 2011 Steady-state kinetics study showed that it initially behaved as a competitive-type inhibitor with a K(i) value of 5.7 x 10(-9) M, then after a few minutes it formed a tight complex with XOR via a Mo-oxygen-carbon atom covalent linkage, as reported previously (Proc Natl Acad Sci USA 101:7931-7936, 2004). Carbon 206-212 xanthine dehydrogenase Rattus norvegicus 186-189 20952484-6 2011 Crystallographic analysis of the charge-transfer complex indicated that a Mo-nitrogen-carbon bond was formed between molybdenum of XOR and the nitrile group of trihydroxy-FYX-051. Carbon 86-92 xanthine dehydrogenase Rattus norvegicus 131-134 19220782-6 2009 Additionally, the novel isoform was able to complement the growth deficiency of the yeast FBP1 deletion fed with a non-fermentable carbon source. Carbon 131-137 fructose 1,6-bisphosphate 1-phosphatase Saccharomyces cerevisiae S288C 90-94 19463565-1 2009 A novel amperometric immunosensor for determination of human serum chorionic gonadotrophin (hCG) was constructed by immobilizing hCG antibody with nano-gold and chitosan (CHIT) hybrid film electrochemical co-deposited on a glassy carbon electrode. Carbon 230-236 chorionic gonadotropin subunit beta 5 Homo sapiens 61-96 19463565-1 2009 A novel amperometric immunosensor for determination of human serum chorionic gonadotrophin (hCG) was constructed by immobilizing hCG antibody with nano-gold and chitosan (CHIT) hybrid film electrochemical co-deposited on a glassy carbon electrode. Carbon 230-236 chorionic gonadotropin subunit beta 5 Homo sapiens 92-95 22073143-3 2011 We uncover a novel pathway for ATP generation that involves reactions from serine biosynthesis, one-carbon metabolism and the glycine cleavage system, and show that the pathway is transcriptionally upregulated in an inducible murine model of Myc-driven liver tumorigenesis. Carbon 100-106 myelocytomatosis oncogene Mus musculus 242-245 28177792-5 2017 Among the carbon sources metabolized by Aeromonas in vitro, some were found to be components of intestinal mucin, including aspartic acid, glutamic acid, l-serine, galactose, N-acetyl-glucosamine, and glucose, which were used by all strains tested. Carbon 10-16 LOC100508689 Homo sapiens 107-112 21980519-1 2011 BACKGROUND: In filamentous ascomycete fungi, the utilization of alternate carbon sources is influenced by the zinc finger transcription factor CreA/CRE-1, which encodes a carbon catabolite repressor protein homologous to Mig1 from Saccharomyces cerevisiae. Carbon 74-80 transcription factor MIG1 Saccharomyces cerevisiae S288C 221-225 21980519-1 2011 BACKGROUND: In filamentous ascomycete fungi, the utilization of alternate carbon sources is influenced by the zinc finger transcription factor CreA/CRE-1, which encodes a carbon catabolite repressor protein homologous to Mig1 from Saccharomyces cerevisiae. Carbon 171-177 transcription factor MIG1 Saccharomyces cerevisiae S288C 221-225 19376129-3 2009 Carbon substitution at the N7 atom of purine nucleoside triphosphates, which disrupts Hoogsteen base pairing, only slightly inhibited DNA synthesis opposite template pyrimidines by pol iota, which was not substantially different from human pols eta and kappa. Carbon 0-6 endothelin receptor type A Homo sapiens 245-248 29740996-2 2017 The results showed that the carbon storage of karst plantations in Guangxi changed in an increasing order of young plantation (86.03 t hm-2), near-mature plantation (110.63 t hm-2), middle-aged plantation (112.11 t hm-2), mature plantation (149.1 t hm-2), and then over-mature plantation (244.38 t hm-2). Carbon 28-34 cholinergic receptor muscarinic 2 Homo sapiens 135-139 18977086-6 2009 The activated carbon prepared under optimum conditions was mesoporous with BET surface area of 1141 m(2)/g, total pore volume of 0.6 cm(3)/g and average pore diameter of 2.5 nm. Carbon 14-20 delta/notch like EGF repeat containing Homo sapiens 75-78 29740996-8 2017 The soil organic carbon storage over the whole soil profile ranged from 51.75 t hm-2 to 81.21 t hm-2. Carbon 17-23 cholinergic receptor muscarinic 2 Homo sapiens 80-84 21701577-1 2011 BACKGROUND: The elongase of long chain fatty acids family 6 (ELOVL6) is an enzyme that specifically catalyzes the elongation of saturated and monounsaturated fatty acids with 12, 14 and 16 carbons. Carbon 189-196 ELOVL fatty acid elongase 6 Homo sapiens 61-67 29740996-8 2017 The soil organic carbon storage over the whole soil profile ranged from 51.75 t hm-2 to 81.21 t hm-2. Carbon 17-23 cholinergic receptor muscarinic 2 Homo sapiens 96-100 29740996-10 2017 The carbon storage for aboveground and underground parts were 22.80-141.72 t hm-2 and 62.30-102.66 t hm-2, respectively. Carbon 4-10 cholinergic receptor muscarinic 2 Homo sapiens 77-81 19463173-5 2009 RESULTS: Peptide 5nd (Tyr-Trp-c [Cys-Lys-Gly-Leu-Cys]-Lys-NH2, S-S) blocks the RGS4-Galphao interaction with an IC50 of 28 microM. Carbon 30-31 regulator of G protein signaling 4 Homo sapiens 79-83 32263951-0 2017 A universal fluorometric assay strategy for glycosidases based on functional carbon quantum dots: beta-galactosidase activity detection in vitro and in living cells. Carbon 77-83 galactosidase beta 1 Homo sapiens 98-116 19463173-5 2009 RESULTS: Peptide 5nd (Tyr-Trp-c [Cys-Lys-Gly-Leu-Cys]-Lys-NH2, S-S) blocks the RGS4-Galphao interaction with an IC50 of 28 microM. Carbon 30-31 G protein subunit alpha o1 Homo sapiens 84-91 20950836-2 2011 The TOX method involves concentration of organic halogens from water by adsorption onto activated carbon (AC). Carbon 98-104 thymocyte selection associated high mobility group box Homo sapiens 4-7 20950836-2 2011 The TOX method involves concentration of organic halogens from water by adsorption onto activated carbon (AC). Carbon 106-108 thymocyte selection associated high mobility group box Homo sapiens 4-7 28103016-4 2017 In this work, SnS2 with a unique nanowall array (NWA) structure is fabricated by one-step pulsed spray evaporation chemical vapor deposition (PSE-CVD), which could be used directly as binder-free and carbon-free anodes for SIBs. Carbon 200-206 sodium voltage-gated channel alpha subunit 11 Homo sapiens 14-18 21187649-1 2010 We presently found that medium-chain fatty acids (MCFAs) with 8-12 carbons and their esters facilitated activation (phosphorylation) of mitogen-activated protein kinases (MAPK)/extracellular signal-regulated kinases (ERK) 1/2 of cultured embryonic cortical/hippocampal neurons. Carbon 67-74 mitogen activated protein kinase 3 Rattus norvegicus 177-225 19466848-2 2009 Diamond transforms to a mechanically stable cubic structure (P4(1)32) at 2.5 TPa and 300 K. At 4000 K and 2 TPa, simple cubic carbon SC1 (Pm-3m) is obtained from cubic diamond. Carbon 126-132 transcription factor 19 Homo sapiens 133-136 19466848-3 2009 The high-pressure tetrahedrally coordinated BC8 (Ia-3) structure of carbon is obtained by decompression of the SC1 structure at 1 TPa and 5000 K. At 3000 K, with decompression of SC1 carbon to 1 TPa, two new metastable tetrahedrally coordinated structures form, MP8 (P2/c) and OP8 (Pccn) with higher density than that of cubic diamond. Carbon 68-74 transcription factor 19 Homo sapiens 111-114 19466848-3 2009 The high-pressure tetrahedrally coordinated BC8 (Ia-3) structure of carbon is obtained by decompression of the SC1 structure at 1 TPa and 5000 K. At 3000 K, with decompression of SC1 carbon to 1 TPa, two new metastable tetrahedrally coordinated structures form, MP8 (P2/c) and OP8 (Pccn) with higher density than that of cubic diamond. Carbon 68-74 transcription factor 19 Homo sapiens 179-182 19466848-3 2009 The high-pressure tetrahedrally coordinated BC8 (Ia-3) structure of carbon is obtained by decompression of the SC1 structure at 1 TPa and 5000 K. At 3000 K, with decompression of SC1 carbon to 1 TPa, two new metastable tetrahedrally coordinated structures form, MP8 (P2/c) and OP8 (Pccn) with higher density than that of cubic diamond. Carbon 183-189 transcription factor 19 Homo sapiens 179-182 27943312-4 2017 Slopes of regressions between accumulation of 13 C-labelled carbon and 15 N-labelled N were higher for LHT1-overexpressing plants than wild type plants, while plants lacking expression of LHT1 did not display a significant regression between the two isotopes. Carbon 49-50 lysine histidine transporter 1 Arabidopsis thaliana 103-107 19329666-1 2009 Engineered Saccharomyces cerevisiae strains overexpressing GPD1, which codes for glycerol-3-phosphate dehydrogenase, and lacking the acetaldehyde dehydrogenase Ald6 display large-scale diversion of the carbon flux from ethanol toward glycerol without accumulating acetate. Carbon 202-208 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 81-115 19329666-1 2009 Engineered Saccharomyces cerevisiae strains overexpressing GPD1, which codes for glycerol-3-phosphate dehydrogenase, and lacking the acetaldehyde dehydrogenase Ald6 display large-scale diversion of the carbon flux from ethanol toward glycerol without accumulating acetate. Carbon 202-208 aldehyde dehydrogenase (NADP(+)) ALD6 Saccharomyces cerevisiae S288C 160-164 19233899-3 2009 The 3"-C-branched p-methylphenyl (compound 1) and 3-CF(3)-4-Cl-phenyl (compound 7) thiourea derivatives of beta-dThd showed competitive inhibition of TK-2 when dThd was used as the variable substrate (K(i) values, 0.40 and 0.05 microM, respectively), but uncompetitive inhibition in the presence of variable concentrations of ATP (K(i) values, 15 and 2.0 microM, respectively). Carbon 7-8 thymidine kinase 2 Homo sapiens 150-154 20444205-3 2010 The ear of gln1-3 and gln1-3/gln1-4 had a higher free amino acid content and a lower C/N ratio, when compared to the wild type. Carbon 85-86 glutamine synthetase root isozyme 3 Zea mays 11-17 20444205-3 2010 The ear of gln1-3 and gln1-3/gln1-4 had a higher free amino acid content and a lower C/N ratio, when compared to the wild type. Carbon 85-86 glutamine synthetase root isozyme 3 Zea mays 22-28 20800353-3 2010 Our sample of GNS(PF6) was developed for the removal of Pb(II) or Cd(II) ions from water, and the determined adsorption capacities are 406.6 mg/g (pH=5.1) for Pb(II) and 73.42 mg/g (pH=6.2) for Cd(II), which is much higher than that by our previous sample of GNS(C8P) and carbon nanotube. Carbon 272-278 sperm associated antigen 17 Homo sapiens 18-21 27943312-4 2017 Slopes of regressions between accumulation of 13 C-labelled carbon and 15 N-labelled N were higher for LHT1-overexpressing plants than wild type plants, while plants lacking expression of LHT1 did not display a significant regression between the two isotopes. Carbon 60-66 lysine histidine transporter 1 Arabidopsis thaliana 103-107 28150830-3 2017 Indeed, the lifetime thermal sensitivity of Ag2S NCs has been found to be as large as 3-4% C-1 at an operating wavelength of 1250 nm. Carbon 50-51 angiotensin II receptor type 1 Homo sapiens 44-48 20883019-4 2010 We find that the early actinides (Pa-Np) are characterized by localized f orbitals and essentially ionic bonding, whereas the f orbitals in the later members of the series (Pu, Am) exhibit significant interaction and spin delocalization into the carbon- and nitrogen-based ligand orbitals. Carbon 246-252 adenosine deaminase 2 Homo sapiens 34-39 19201098-2 2009 Conventionally, the main transition carbide is described as epsilon carbide, with a composition of approximately Fe(2.4)C. However, earlier one-dimensional atom probe (1DAP) results indicated the existence of carbon-rich regions having much lower carbon contents, with maxima of around 10at%. Carbon 209-215 death associated protein Homo sapiens 169-172 19241374-4 2009 In this study, we determined the solution structure of the Fn14 CRD (Glu28-Ala70) by heteronuclear NMR, with a (13)C-/(15)N-labeled sample. Carbon 64-65 TNF receptor superfamily member 12A Homo sapiens 59-63 28106192-1 2017 A novel N-doped MOF-based hierarchical carbon fiber (NPCF) towards supercapacitors was prepared by the pyrolysis of MOF nanofibers. Carbon 39-45 lysine acetyltransferase 8 Homo sapiens 16-19 19173070-1 2009 The enzyme myo-inositol oxygenase (MIOX) catalyzes conversion of myo-inositol (cyclohexan-1,2,3,5/4,6-hexa-ol or MI) to d-glucuronate (DG), initiating the only known pathway in humans for catabolism of the carbon skeleton of cell-signaling inositol (poly)phosphates and phosphoinositides. Carbon 206-212 myo-inositol oxygenase Homo sapiens 11-33 20807862-3 2010 MYB75, also called PRODUCTION OF ANTHOCYANIN PIGMENT1, is a known regulator of the anthocyanin branch of the phenylpropanoid pathway in Arabidopsis (Arabidopsis thaliana), but how this regulation might impact other aspects of carbon metabolism is unclear. Carbon 226-232 production of anthocyanin pigment 1 Arabidopsis thaliana 0-5 19173070-1 2009 The enzyme myo-inositol oxygenase (MIOX) catalyzes conversion of myo-inositol (cyclohexan-1,2,3,5/4,6-hexa-ol or MI) to d-glucuronate (DG), initiating the only known pathway in humans for catabolism of the carbon skeleton of cell-signaling inositol (poly)phosphates and phosphoinositides. Carbon 206-212 myo-inositol oxygenase Homo sapiens 35-39 28106192-1 2017 A novel N-doped MOF-based hierarchical carbon fiber (NPCF) towards supercapacitors was prepared by the pyrolysis of MOF nanofibers. Carbon 39-45 lysine acetyltransferase 8 Homo sapiens 116-119 20807862-6 2010 Transcript profiles from the myb75-1 inflorescence stem revealed marked up-regulation in the expression of a suite of genes associated with lignin biosynthesis and cellulose deposition, as well as cell wall modifying proteins and genes involved in photosynthesis and carbon assimilation. Carbon 267-273 production of anthocyanin pigment 1 Arabidopsis thaliana 29-36 28106192-2 2017 Due to its unique 1D hollow structures, the NPCF exhibits better energy storage capacity than the other previously reported MOF-derived carbon materials. Carbon 136-142 lysine acetyltransferase 8 Homo sapiens 124-127 27723738-7 2017 The MOF-based device shows an areal capacitance that exceeds those of most carbon-based materials and capacity retention greater than 90% over 10,000 cycles, in line with commercial devices. Carbon 75-81 lysine acetyltransferase 8 Homo sapiens 4-7 21805859-1 2010 It has been shown that calix[4]arene C-99 inhibited myosin subfragment-1 ATPase of myometrium. Carbon 37-38 dynein axonemal heavy chain 8 Homo sapiens 73-79 19334611-6 2009 Mutation sup35-AGG1 (ATG1-->AGG) causes the lethal effect in cells grown on media containing glucose as the sole source of carbon. Carbon 126-132 translation termination factor GTPase eRF3 Saccharomyces cerevisiae S288C 9-14 19238984-5 2009 The 2-CIBP adsorption and dechlorination rate constants were estimated through simple first-order reaction kinetic models with an assumption for unextractable portion of carbon in RAC. Carbon 170-176 calcium and integrin binding 1 Homo sapiens 6-10 28680578-3 2017 Using cell culture models and transgenic mice expressing PAH-causing BMPR2 mutations, we found that the pulmonary endothelium in PAH shunts significantly more glutamine carbon into the tricarboxylic acid (TCA) cycle than wild-type endothelium. Carbon 169-175 bone morphogenetic protein receptor, type II (serine/threonine kinase) Mus musculus 69-74 20877801-0 2009 The reaction mechanism of the molybdenum hydroxylase xanthine oxidoreductase: evidence against the formation of intermediates having metal-carbon bonds. Carbon 139-145 xanthine dehydrogenase Homo sapiens 53-76 20815084-3 2010 It was previously shown that a S. cerevisiae strain with non-functional copies of GPM1 can only grow when glycerol and ethanol are both present as carbon sources, whilst addition of glucose was shown to strongly inhibit growth. Carbon 147-153 phosphoglycerate mutase GPM1 Saccharomyces cerevisiae S288C 82-86 27513684-1 2017 Glucoamylase-displayed bacteria (GA-bacteria) and glucose dehydrogenase-displayed bacteria (GDH-bacteria) were co-immobilized on multi-walled carbon nanotubes (MWNTs) modified glassy carbon electrode (GCE) to construct GA-bacteria/GDH-bacteria/MWNTs/GCE biosensor. Carbon 183-189 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 50-71 20653776-2 2010 Deletion of MRS2, LPE10 or both results in a petite phenotype, which exhibits a respiratory growth defect on nonfermentable carbon sources. Carbon 124-130 Mrs2p Saccharomyces cerevisiae S288C 12-16 19107399-0 2008 Carbon source dependent dynamics of the Ccr4-Not complex in Saccharomyces cerevisiae. Carbon 0-6 CCR4-NOT core exoribonuclease subunit CCR4 Saccharomyces cerevisiae S288C 40-44 27846374-3 2017 Here we show that carbon-based nanodiamonds (NDs) coated with ubiquitin (Ub) bind to autophagy receptors (SQSTM1 [sequestosome 1], OPTN [optineurin], and CALCOCO2/NDP52 [calcium binding and coiled-coil domain 2]) and are then linked to MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3) for entry into the selective autophagy pathway. Carbon 18-24 calcium binding and coiled-coil domain 2 Homo sapiens 154-162 18852288-6 2008 The GTPBP3 N-terminal domain mediates a potassium-independent dimerization, which appears as an evolutionarily conserved property of the protein family, probably related to the construction of the binding site for the one-carbon-unit donor in the modification reaction. Carbon 222-228 GTP binding protein 3, mitochondrial Homo sapiens 4-10 18937460-1 2008 The potassium graphite reduction of L:PCl3 leads to the formation of carbene-stabilized diphosphorus molecules, L:P-P:L, 1 (L: = :C{N(2,6-Pri2C6H3)CH}2) and 2 (L: = :C{N(2,4,6-Me3C6H2)CH}2), respectively. Carbon 130-131 PHD finger protein 19 Homo sapiens 38-42 20660228-0 2010 Light and low-CO2-dependent LCIB-LCIC complex localization in the chloroplast supports the carbon-concentrating mechanism in Chlamydomonas reinhardtii. Carbon 91-97 uncharacterized protein Chlamydomonas reinhardtii 33-37 21588544-1 2010 In the title compound, [RuCl(C(10)H(14))(C(14)H(16)N(2))]PF(6), the aromatic ring of the isopropyl-methyl-benzene fragment shows an eta(6)-arene coordination to the ruthenium atom. Carbon 26-27 sperm associated antigen 17 Homo sapiens 57-62 27846374-3 2017 Here we show that carbon-based nanodiamonds (NDs) coated with ubiquitin (Ub) bind to autophagy receptors (SQSTM1 [sequestosome 1], OPTN [optineurin], and CALCOCO2/NDP52 [calcium binding and coiled-coil domain 2]) and are then linked to MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3) for entry into the selective autophagy pathway. Carbon 18-24 calcium binding and coiled-coil domain 2 Homo sapiens 163-168 28380233-3 2017 In the structures of complexes 1, 2 and 4 Cu(I) cation possesses a tetrahedral environment formed by the C=C bond of one organic cation Hapn, the N atom of cyano group from another Hapn moiety, and two O atoms (from NO3- anions in 1, from H2O molecules in 2) or N atoms (NH2SO3- anions in 4). Carbon 42-43 alanyl aminopeptidase, membrane Homo sapiens 136-140 21253464-5 2010 The mutant strains aim45 and yor356w/cir2 displayed better growth on several non-fermentable carbon sources, which depended on the component of the electron transport chain that accepts the electrons resulting from its mitochondrial oxidation. Carbon 93-99 Aim45p Saccharomyces cerevisiae S288C 19-24 21253464-7 2010 Other phenotypes identified suggest that AIM45, YGR207c/CIR1 and YOR356w/CIR2 can protect cells from oxidative and heat stress, which encompass increased heat stress sensitivity, superoxide sensitivity, both only on non-fermentable carbon sources. Carbon 232-238 Aim45p Saccharomyces cerevisiae S288C 41-46 18820081-7 2008 Transcriptome analysis of the gapc-1 mutants unveils a differential accumulation of transcripts encoding for enzymes involved in carbon partitioning. Carbon 129-135 glyceraldehyde-3-phosphate dehydrogenase C subunit 1 Arabidopsis thaliana 30-36 28380233-3 2017 In the structures of complexes 1, 2 and 4 Cu(I) cation possesses a tetrahedral environment formed by the C=C bond of one organic cation Hapn, the N atom of cyano group from another Hapn moiety, and two O atoms (from NO3- anions in 1, from H2O molecules in 2) or N atoms (NH2SO3- anions in 4). Carbon 42-43 alanyl aminopeptidase, membrane Homo sapiens 181-185 28380233-4 2017 In compound 3 strongly pronounced trigonal-pyramidal coordination environment of Cu(I) is formed by a mid-point of C=C-bond of one Hapn cation, nitrogen atom (of cyano group) of another Hapn unit, O atom of H2O molecule in the basal plane, and F atom of BF4- anion at the apical position. Carbon 81-82 alanyl aminopeptidase, membrane Homo sapiens 131-135 18834097-1 2008 The formation mechanism of linear-carbon-chain molecules, C n O ( n = 2 - 9), synthesized in the discharge of C 3O 2 has been investigated on the basis of detailed analyses of previously obtained FTMW spectroscopic data. Carbon 34-40 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 58-63 18834097-3 2008 The active chemicals in the reaction system include :C and :CCO only, and the observed products exclusively consist of C n O, leading to a likely formation mechanism of the atomic-carbon addition and ring opening reaction. Carbon 180-186 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 119-124 28380233-4 2017 In compound 3 strongly pronounced trigonal-pyramidal coordination environment of Cu(I) is formed by a mid-point of C=C-bond of one Hapn cation, nitrogen atom (of cyano group) of another Hapn unit, O atom of H2O molecule in the basal plane, and F atom of BF4- anion at the apical position. Carbon 81-82 alanyl aminopeptidase, membrane Homo sapiens 186-190 20420934-5 2010 The fractions of residual G1-PCC breaks after 24 h post-irradiation and half time, which is the time point where 50% of initially measured G1-PCC breaks are rejoined (t1/2), of the slow components of rejoining in carbon- and neon-ion irradiated cells were different from those of silicon-ion irradiated cells. Carbon 213-219 crystallin gamma D Homo sapiens 29-32 28380233-4 2017 In compound 3 strongly pronounced trigonal-pyramidal coordination environment of Cu(I) is formed by a mid-point of C=C-bond of one Hapn cation, nitrogen atom (of cyano group) of another Hapn unit, O atom of H2O molecule in the basal plane, and F atom of BF4- anion at the apical position. Carbon 115-116 alanyl aminopeptidase, membrane Homo sapiens 131-135 28068148-4 2017 The results indicate that 247 g d-1 carbon was imported into the system from stored food. Carbon 36-42 leiomodin 1 Homo sapiens 32-35 20303745-2 2010 Experimental results show that the BET surface area of activated carbons irrespective of the activation agent resulted in surface area in excess of 2000 m(2)/g. Carbon 65-72 delta/notch like EGF repeat containing Homo sapiens 35-38 20303745-4 2010 The activated carbon prepared using CO(2) activation has the largest BET surface area, however the activation time is approximately 2.5 times higher than the activation using steam or mixture of steam-CO(2). Carbon 14-20 delta/notch like EGF repeat containing Homo sapiens 69-72 18558101-1 2008 Sphingosine-1-phosphate lyase (SPL) is a highly conserved enzyme that catalyses the final step of sphingolipid degradation, namely the irreversible cleavage of the carbon chain at positions 2-3 of a long-chain base phosphate (LCBP), thereby yielding a long-chain aldehyde and phosphoethanolamine. Carbon 164-170 sphingosine-1-phosphate lyase 1 Homo sapiens 0-29 18558101-1 2008 Sphingosine-1-phosphate lyase (SPL) is a highly conserved enzyme that catalyses the final step of sphingolipid degradation, namely the irreversible cleavage of the carbon chain at positions 2-3 of a long-chain base phosphate (LCBP), thereby yielding a long-chain aldehyde and phosphoethanolamine. Carbon 164-170 sphingosine-1-phosphate lyase 1 Homo sapiens 31-34 29634169-5 2017 The BET specific surface area of the carbon material prepared by the heat treatment at 800 degrees C for 1 h under flowing N2 was related to the pretreatment conditions, and the specific surface areas of the samples were found to be related to the lignin percentage. Carbon 37-43 delta/notch like EGF repeat containing Homo sapiens 4-7 18687061-5 2008 Gal4p, the archetypical member of this family, is responsible for the expression of the GAL genes when galactose is utilized as a carbon source. Carbon 130-136 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 0-5 21090302-1 2010 The PBS material that in the form of insoluble biodegradable polymers pellets was investigated as the solid carbon source and the biofilm carrier for nitrate removal from wastewater. Carbon 108-114 cholinergic receptor muscarinic 3 Homo sapiens 4-7 21090302-6 2010 The kinetic experimental results show that the denitrification rate of PBS as the solid carbon source and the biofilm carrier corresponds to first-order kinetics. Carbon 88-94 cholinergic receptor muscarinic 3 Homo sapiens 71-74 31275011-5 2017 We previously showed that the plant specific ubiquitin ligase ATL31 regulates the carbon/nitrogen-nutrient response and pathogen resistance in Arabidopsis, and we identified and characterized the basic biochemical function of an ATL31 homologue in tomato plants (Solanum lycopersicum L.). Carbon 82-88 carbon/nitrogen insensitive 1 Arabidopsis thaliana 62-67 19068615-7 2008 The partition coefficient (Kp) increased with the particular organic carbon content of SPM and salinity of water and decreased with the SPM content of samples, which were consistent with the PAH partition theory. Carbon 69-75 phenylalanine hydroxylase Homo sapiens 191-194 18682652-4 2008 In the case of the compounds studied here, the long distances between the O atom of the carbonyl group and the gamma-H atom, and between the C atom of the carbonyl group and the gamma-C atom preclude Yang photocyclization in the crystals. Carbon 141-142 interleukin 2 receptor subunit gamma Homo sapiens 178-185 31275011-5 2017 We previously showed that the plant specific ubiquitin ligase ATL31 regulates the carbon/nitrogen-nutrient response and pathogen resistance in Arabidopsis, and we identified and characterized the basic biochemical function of an ATL31 homologue in tomato plants (Solanum lycopersicum L.). Carbon 82-88 carbon/nitrogen insensitive 1 Arabidopsis thaliana 229-234 28230922-3 2017 ALDH-positive cells were isolated by a fluorescence-activated cell sorting technique from Lewis rat"s stromal-vascular-fraction (SVF) and transplanted with c-GAG scaffolds in a rat full-thickness skin wound model. Carbon 14-15 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 0-4 18438922-4 2008 We detected a significant decrease of myelin basic protein (MBP) mRNA and protein at early postnatal periods in poly-I:C mice. Carbon 119-120 myelin basic protein Mus musculus 38-58 18438922-4 2008 We detected a significant decrease of myelin basic protein (MBP) mRNA and protein at early postnatal periods in poly-I:C mice. Carbon 119-120 myelin basic protein Mus musculus 60-63 20463021-3 2010 Two multifunctional peroxisomal isozymes, MFP2 and AIM1, both with 2-trans-enoyl-CoA hydratase and l-3-hydroxyacyl-CoA dehydrogenase activities, function in mouse ear cress (Arabidopsis thaliana) peroxisomal beta-oxidation, where fatty acids are degraded by the sequential removal of two carbon units. Carbon 288-294 multifunctional protein 2 Arabidopsis thaliana 42-46 27940912-8 2016 A primary intrinsic 13C KIE of 1.04, an inverse intrinsic alpha-secondary CD3 KIE of 0.90, and a small but statistically significant inverse CD3 BIE of 0.96, in combination with computational modeling, revealed that SET8-catalyzed methylation proceeds through an early, asymmetrical SN2 transition state with the C-N and C-S distances of 2.35-2.40 A and 2.00-2.05 A, respectively. Carbon 22-23 lysine methyltransferase 5A Homo sapiens 216-220 20544751-1 2010 The interaction of [Ru(eta(6)-C(10)H(8))(Cp)](+) (Cp=C(5)H(5)) with aromatic amino acids (L-phenylalanine, L-tyrosine, L-tryptophane, D-phenylglycine, and L-threo-3-phenylserine) under visible-light irradiation gives the corresponding [Ru(eta(6)-amino acid)(Cp)](+) complexes in near-quantitative yield. Carbon 30-31 endothelin receptor type A Homo sapiens 23-26 20362394-3 2010 BET surface area and total pore volume of active carbon (AC) in the active carbon-ceramic sphere increase with increasing KOH-to-carbon ratio, and AC in the sample KC-120 possesses values as high as 1100 m(2) g(-1) and 0.69 cm(3) g(-1) (carbon percentage: 4.73 wt.%), especially. Carbon 75-81 delta/notch like EGF repeat containing Homo sapiens 0-3 20362394-3 2010 BET surface area and total pore volume of active carbon (AC) in the active carbon-ceramic sphere increase with increasing KOH-to-carbon ratio, and AC in the sample KC-120 possesses values as high as 1100 m(2) g(-1) and 0.69 cm(3) g(-1) (carbon percentage: 4.73 wt.%), especially. Carbon 75-81 delta/notch like EGF repeat containing Homo sapiens 0-3 18507803-0 2008 The lack of alternative oxidase at low temperature leads to a disruption of the balance in carbon and nitrogen metabolism, and to an up-regulation of antioxidant defence systems in Arabidopsis thaliana leaves. Carbon 91-97 alternative oxidase 2 Arabidopsis thaliana 12-31 27778379-0 2016 Controlling the BET Surface Area of Porous Carbon by Using the Cd/C Ratio of a Cd-MOF Precursor and Enhancing the Capacitance by Activation with KOH. Carbon 43-49 delta/notch like EGF repeat containing Homo sapiens 16-19 18594727-0 2008 Polycarbide nickel clusters containing interstitial Ni(eta2-C2)4 and Ni2(micro-eta2-C2)4 acetylide moieties: mimicking the supersaturated Ni-C solutions preceding the catalytic growth of CNTs with the structures of [HNi25(C2)4(CO)32]3- and [Ni22(C2)4(CO)28Cl]3-. Carbon 60-61 DNA polymerase iota Homo sapiens 55-59 18547076-5 2008 The carbon material obtained (denoted as C-ORNL-1) exhibits highly ordered hexagonal mesostructure, with a typical BET surface area of approximately 600 m2/g, pore size of 6.3 nm, and pore volume of approximately 0.60 cm3/g. Carbon 4-10 delta/notch like EGF repeat containing Homo sapiens 115-118 18837363-3 2008 RESULTS: Compared with that of the parent strain, the acetyl-CoA synthase activity of the mutant ACS2-1 increased about 920% and the mutant could use acetate as the sole carbon source for growth (2.6 g/L dry cell weight). Carbon 170-176 acetate--CoA ligase ACS2 Saccharomyces cerevisiae S288C 97-101 18473443-5 2008 The surface carboxylic acid generated is then used to tether an osmium complex, [Os(2,2"-bipyridyl)2(4-aminomethylpyridine)Cl]PF6, to provide a covalently bound redox-active monolayer, E(0) " of 0.29 V (vs Ag/AgCl in phosphate buffer, pH 7.4), on the pretreated glassy carbon electrode. Carbon 269-275 sperm associated antigen 17 Homo sapiens 126-129 18484721-2 2008 eta2-Coordination of Ni(PEt3)2 to the C=C moiety of halogenated vinylarenes is kinetically preferable and is followed by an intramolecular aryl-halide bond activation process. Carbon 5-6 DNA polymerase iota Homo sapiens 0-4 18484721-2 2008 eta2-Coordination of Ni(PEt3)2 to the C=C moiety of halogenated vinylarenes is kinetically preferable and is followed by an intramolecular aryl-halide bond activation process. Carbon 38-39 DNA polymerase iota Homo sapiens 0-4 18378664-8 2008 Quantification of citrate synthase (gltA) levels demonstrated a stimulation of Geobacteraceae activity during metal reduction in carbon-amended microcosms, with the highest expression observed in the glucose treatment. Carbon 129-135 citrate synthase Homo sapiens 18-34 20362394-3 2010 BET surface area and total pore volume of active carbon (AC) in the active carbon-ceramic sphere increase with increasing KOH-to-carbon ratio, and AC in the sample KC-120 possesses values as high as 1100 m(2) g(-1) and 0.69 cm(3) g(-1) (carbon percentage: 4.73 wt.%), especially. Carbon 75-81 delta/notch like EGF repeat containing Homo sapiens 0-3 20568755-3 2010 The Ni-C bond lengths of 1.994(3) A in 1 and 2.015(3) A in 2 are comparable to that in the Ni(III)-methyl state of MCR (approximately 2.04 A) (Sarangi, R.; Dey, M.; Ragsdale, S. W. Biochemistry 2009, 48, 3146). Carbon 7-8 nuclear receptor subfamily 3 group C member 2 Homo sapiens 115-118 20518495-2 2010 They all start from the carboxylic acid [Fe(eta(5)-C(5)H(4)COOH)(eta(6)-C(6)Me(6))][PF(6)], 2, or its acyl chloride derivative [Fe(eta(5)-C(5)H(4)COCl)(eta(6)-C(6)Me(6))][PF(6)], 3. Carbon 50-52 endothelin receptor type A Homo sapiens 44-47 20518495-2 2010 They all start from the carboxylic acid [Fe(eta(5)-C(5)H(4)COOH)(eta(6)-C(6)Me(6))][PF(6)], 2, or its acyl chloride derivative [Fe(eta(5)-C(5)H(4)COCl)(eta(6)-C(6)Me(6))][PF(6)], 3. Carbon 50-52 endothelin receptor type A Homo sapiens 65-68 20518495-2 2010 They all start from the carboxylic acid [Fe(eta(5)-C(5)H(4)COOH)(eta(6)-C(6)Me(6))][PF(6)], 2, or its acyl chloride derivative [Fe(eta(5)-C(5)H(4)COCl)(eta(6)-C(6)Me(6))][PF(6)], 3. Carbon 50-52 endothelin receptor type A Homo sapiens 65-68 20518495-2 2010 They all start from the carboxylic acid [Fe(eta(5)-C(5)H(4)COOH)(eta(6)-C(6)Me(6))][PF(6)], 2, or its acyl chloride derivative [Fe(eta(5)-C(5)H(4)COCl)(eta(6)-C(6)Me(6))][PF(6)], 3. Carbon 50-52 endothelin receptor type A Homo sapiens 65-68 20439704-9 2010 Reduced growth of wild-type plants in 28-h days and lhy/cca1 mutants in 24-h days was attributable to the inappropriate rate of starch degradation and the consequent carbon starvation at the end of night. Carbon 166-172 circadian clock associated 1 Arabidopsis thaliana 56-60 20369854-0 2010 Formation of a quinoneimine intermediate of 4-fluoro-N-methylaniline by FMO1: carbon oxidation plus defluorination. Carbon 78-84 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 72-76 20369854-2 2010 FMO1 catalyzed a carbon oxidation reaction coupled with defluorination that led to the formation of 4-N-methylaminophenol, which was a reaction first reported by Boersma et al. Carbon 17-23 flavin containing dimethylaniline monoxygenase 1 Homo sapiens 0-4 20359018-1 2010 PtPd nanoparticles on carbon black were prepared to investigate the role of Pd in the anode and cathode of a direct methanol fuel cell (DMFC). Carbon 22-28 protein tyrosine phosphatase receptor type D Homo sapiens 0-4 20200070-5 2010 Notably, the metabolic alterations in the SnRK2.6 overexpressors were accompanied by amelioration of those physiological processes that require high levels of carbon and energy input, such as plant growth and seed production. Carbon 159-165 Protein kinase superfamily protein Arabidopsis thaliana 42-49 20304787-7 2010 However, the carbon (C)/N ratios and carbohydrate levels in aox1a plants were similar to those in the WT under low-N stress. Carbon 13-19 alternative oxidase 1A Arabidopsis thaliana 60-65 20304787-7 2010 However, the carbon (C)/N ratios and carbohydrate levels in aox1a plants were similar to those in the WT under low-N stress. Carbon 21-23 alternative oxidase 1A Arabidopsis thaliana 60-65 21579212-1 2010 In the title salt, C(18)H(19)N(4)O(+) PF(6) (-), the dihedral angle between the benzimidazolium and benzimidazole ring systems is 16.24 (2) . Carbon 19-20 sperm associated antigen 17 Homo sapiens 38-43 20121055-4 2010 The potential for the oxidation of glucose at the GDH/NAD(+)/MWCNT-modified electrode remains very close to that for NADH oxidation at the MWCNT-modified electrode, but it is more negative than those for the oxidation of glucose at the MWCNT-modified electrode and for NADH oxidation at a bare glassy carbon electrode. Carbon 301-307 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 50-53 20101436-0 2010 Heterologous expression of yeast Hxt2 in Arabidopsis thaliana alters sugar uptake, carbon metabolism and gene expression leading to glucose tolerance of germinating seedlings. Carbon 83-89 hexose transporter HXT2 Saccharomyces cerevisiae S288C 33-37 20101436-13 2010 Results suggest that the Hxt2 transgene altered some developmental processes related to the perception of high carbon availability after the germination stage. Carbon 111-117 hexose transporter HXT2 Saccharomyces cerevisiae S288C 25-29 20183815-3 2010 The SnO nanosheets form a porous thin film on substrates such as indium tin oxide and carbon nanofiber (CNF). Carbon 86-92 strawberry notch homolog 1 Homo sapiens 4-7 20158207-9 2010 It was demonstrated that slight oxidation of AC with ozone basically inhibited its reduction for TOX and meanwhile maintained its adsorption capacity for TOX. Carbon 45-47 thymocyte selection associated high mobility group box Homo sapiens 97-100 20158207-9 2010 It was demonstrated that slight oxidation of AC with ozone basically inhibited its reduction for TOX and meanwhile maintained its adsorption capacity for TOX. Carbon 45-47 thymocyte selection associated high mobility group box Homo sapiens 154-157 19945216-1 2010 The performance of a carbon-mineral composite adsorbent used in a fixed bed column for the removal of ammoniacal nitrogen and aggregate organic pollutant (COD), which are commonly found in landfill leachate, was evaluated. Carbon 21-27 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 155-158 19833433-5 2010 The proper choice of preparation conditions were resulted in microporous activated carbons with different BET surface areas of 780 (Carbon A, 1:0.5 ZnCl(2)) and 803 (Carbon B, 1:1 ZnCl(2))m(2)/g BET surface area. Carbon 83-90 delta/notch like EGF repeat containing Homo sapiens 106-109 19948730-0 2010 Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos. Carbon 92-98 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 14-42 19766063-1 2010 The electrochemical behaviour of dimethyl-2-oxoglutarate (MOG), a key intermediate in the Krebs cycle and an important nitrogen transporter in the metabolic pathways in biological processes, was investigated by cyclic voltammetry, square wave voltammetry and differential pulse voltammetry using a glassy carbon electrode. Carbon 305-311 myelin oligodendrocyte glycoprotein Homo sapiens 58-61 19793645-4 2010 The results show that activated carbons from pyrolusite-supplemented sewage sludge had up to a 75% higher BET surface area and up to a 66% increase in mesoporosity over ordinary sludge-based activated carbons. Carbon 32-39 delta/notch like EGF repeat containing Homo sapiens 106-109 21579679-1 2010 In the title structure, [CoRu(C(5)H(5))(C(17)H(26)P)(2)Cl]PF(6), the Ru(II) atom is bonded to a cyclo-penta-dienyl ring, a Cl atom and two P atoms of the chelating 1,1"-bis-(dicyclo-hexyl-phosphino)cobaltocenium (di-cypc) ligand, leading to a three-legged piano-stool coordination. Carbon 25-26 sperm associated antigen 17 Homo sapiens 58-63 21579679-1 2010 In the title structure, [CoRu(C(5)H(5))(C(17)H(26)P)(2)Cl]PF(6), the Ru(II) atom is bonded to a cyclo-penta-dienyl ring, a Cl atom and two P atoms of the chelating 1,1"-bis-(dicyclo-hexyl-phosphino)cobaltocenium (di-cypc) ligand, leading to a three-legged piano-stool coordination. Carbon 30-31 sperm associated antigen 17 Homo sapiens 58-63 20023953-5 2010 These results demonstrate that the diinsertion of PhN=C=O into the N-H bond of coordinated amino ligands might proceed in a stepwise manner. Carbon 54-55 carbamoyl-phosphate synthase 1 Homo sapiens 50-53 20185925-8 2010 RESULTS: Costimulation with TNF-alpha and Th2 cytokines (IL-4, IL-13) or with poly(I:C) and Th2 cytokines (IL-4, IL-13) induced TARC production by nasal (polyp and normal) fibroblasts. Carbon 9-10 C-C motif chemokine ligand 17 Homo sapiens 128-132 20157245-9 2010 Therefore, one-carbon metabolism alteration seems to be a cause of deregulation of the equilibrium between GSK3beta and PP2A, leading to abnormal hyperphosphorylated tau. Carbon 15-21 glycogen synthase kinase 3 alpha Homo sapiens 107-115 19303048-2 2009 In our studies we took advantage of their negative charge to study their biological activities after being complexed with carbon nanotubes, a novel vector for vaccine delivery and Tat protein of HIV, a target protein for therapeutic or prophylactic intervention. Carbon 122-128 tyrosine aminotransferase Homo sapiens 180-183 27778379-0 2016 Controlling the BET Surface Area of Porous Carbon by Using the Cd/C Ratio of a Cd-MOF Precursor and Enhancing the Capacitance by Activation with KOH. Carbon 0-1 delta/notch like EGF repeat containing Homo sapiens 16-19 27841388-2 2016 Subsequent carbonization and thermal treatment of CD-MOF-2, the cyclodextrin metal-organic framework, afforded a carbon molecular sieve with a uniform and reduced pore size of ca. Carbon 11-17 lysine acetyltransferase 8 Homo sapiens 53-56 19731956-6 2009 The bis-sulfamates incorporating 8 or 10 carbon atoms showed higher affinity for the tumor-associated hCA IX compared to hCA II, whereas the opposite was true for the monosulfamates. Carbon 41-47 carbonic anhydrase 9 Homo sapiens 102-108 19640775-1 2009 Studies of nonenzymatic electrophilic catalysis of carbon deprotonation of glycine show that pyridoxal 5"-phosphate (PLP) strongly enhances the carbon acidity of alpha-amino acids, but that this is not the overriding mechanistic imperative for cofactor catalysis. Carbon 51-57 pyridoxal phosphatase Homo sapiens 117-120 19640775-1 2009 Studies of nonenzymatic electrophilic catalysis of carbon deprotonation of glycine show that pyridoxal 5"-phosphate (PLP) strongly enhances the carbon acidity of alpha-amino acids, but that this is not the overriding mechanistic imperative for cofactor catalysis. Carbon 144-150 pyridoxal phosphatase Homo sapiens 117-120 19911136-4 2009 In this study, we conducted an inverse modeling analysis to retrieve the spatial pattern of Q(10) in China at 8 km spatial resolution by assimilating data of soil organic carbon into a process-based terrestrial carbon model (CASA model). Carbon 211-217 casein alpha s1 Homo sapiens 225-229 19724814-1 2009 A catalytic amount of electrochemically generated "ArS+" ("ArS+" = ArS(ArSSAr)+) initiates a cation chain reaction of dienes that involves the addition of ArSSAr associated with stereoselective intramolecular carbon-carbon bond formation, and the direct (in-cell) electrolysis of a mixture of a diene and ArSSAr with a catalytic amount of electricity also effectively initiates the reaction. Carbon 209-215 RIEG2 Homo sapiens 51-54 19724814-1 2009 A catalytic amount of electrochemically generated "ArS+" ("ArS+" = ArS(ArSSAr)+) initiates a cation chain reaction of dienes that involves the addition of ArSSAr associated with stereoselective intramolecular carbon-carbon bond formation, and the direct (in-cell) electrolysis of a mixture of a diene and ArSSAr with a catalytic amount of electricity also effectively initiates the reaction. Carbon 209-215 RIEG2 Homo sapiens 59-62 19724814-1 2009 A catalytic amount of electrochemically generated "ArS+" ("ArS+" = ArS(ArSSAr)+) initiates a cation chain reaction of dienes that involves the addition of ArSSAr associated with stereoselective intramolecular carbon-carbon bond formation, and the direct (in-cell) electrolysis of a mixture of a diene and ArSSAr with a catalytic amount of electricity also effectively initiates the reaction. Carbon 209-215 RIEG2 Homo sapiens 59-62 19724814-1 2009 A catalytic amount of electrochemically generated "ArS+" ("ArS+" = ArS(ArSSAr)+) initiates a cation chain reaction of dienes that involves the addition of ArSSAr associated with stereoselective intramolecular carbon-carbon bond formation, and the direct (in-cell) electrolysis of a mixture of a diene and ArSSAr with a catalytic amount of electricity also effectively initiates the reaction. Carbon 216-222 RIEG2 Homo sapiens 51-54 19724814-1 2009 A catalytic amount of electrochemically generated "ArS+" ("ArS+" = ArS(ArSSAr)+) initiates a cation chain reaction of dienes that involves the addition of ArSSAr associated with stereoselective intramolecular carbon-carbon bond formation, and the direct (in-cell) electrolysis of a mixture of a diene and ArSSAr with a catalytic amount of electricity also effectively initiates the reaction. Carbon 216-222 RIEG2 Homo sapiens 59-62 19724814-1 2009 A catalytic amount of electrochemically generated "ArS+" ("ArS+" = ArS(ArSSAr)+) initiates a cation chain reaction of dienes that involves the addition of ArSSAr associated with stereoselective intramolecular carbon-carbon bond formation, and the direct (in-cell) electrolysis of a mixture of a diene and ArSSAr with a catalytic amount of electricity also effectively initiates the reaction. Carbon 216-222 RIEG2 Homo sapiens 59-62 19738041-1 2009 5,10-Methenyltetrahydrofolate synthetase (MTHFS) regulates the flow of carbon through the one-carbon metabolic network, which supplies essential components for the growth and proliferation of cells. Carbon 71-77 methenyltetrahydrofolate synthetase Homo sapiens 0-40 19738041-1 2009 5,10-Methenyltetrahydrofolate synthetase (MTHFS) regulates the flow of carbon through the one-carbon metabolic network, which supplies essential components for the growth and proliferation of cells. Carbon 71-77 methenyltetrahydrofolate synthetase Homo sapiens 42-47 19738041-1 2009 5,10-Methenyltetrahydrofolate synthetase (MTHFS) regulates the flow of carbon through the one-carbon metabolic network, which supplies essential components for the growth and proliferation of cells. Carbon 94-100 methenyltetrahydrofolate synthetase Homo sapiens 0-40 19738041-1 2009 5,10-Methenyltetrahydrofolate synthetase (MTHFS) regulates the flow of carbon through the one-carbon metabolic network, which supplies essential components for the growth and proliferation of cells. Carbon 94-100 methenyltetrahydrofolate synthetase Homo sapiens 42-47 19456182-1 2009 Lignosulfonic acid (LS1) and partially desulfonated lignosulfonic acid (LS2) were oxidatively deposited on a preactivated glassy carbon (GC) electrode, giving rise to redox active films showing three distinct redox couples at midpeak potentials (E degrees ") of 0.22, 0.44, and 0.53 V (vs Ag/AgCl in 0.1 M H(2)SO(4)). Carbon 129-135 serpin family D member 1 Homo sapiens 72-75 19630024-4 2009 The differences in the carbon isotopic compositions of methylboronates between the measured and calculated ranged from -0.20 to 0.12 per thousand, within the specification of the GC/C/IRMS system. Carbon 23-29 guanylate cyclase 2C Homo sapiens 179-188 20628463-6 2009 The loading of SnO(2) on the surface of carbon hollow spheres was processed, and its PL property was also characterized. Carbon 40-46 strawberry notch homolog 1 Homo sapiens 15-18 19625620-0 2009 Sucrose synthase affects carbon partitioning to increase cellulose production and altered cell wall ultrastructure. Carbon 25-31 sucrose synthase Gossypium hirsutum 0-16 19525417-2 2009 The ADE3 gene is known to encode a crucial one-carbon regulon enzyme, tetrahydrofolate synthase, which is involved in the biosynthesis of purine and the amino acids methionine and glycine. Carbon 47-53 tetrahydrofolate synthase Saccharomyces cerevisiae S288C 70-95 19589965-3 2009 TDH-mediated catabolism of threonine takes place in mitochondria to generate glycine and acetyl-coenzyme A (CoA), with glycine facilitating one-carbon metabolism via the glycine cleavage system and acetyl-CoA feeding the tricarboxylic acid cycle. Carbon 144-150 L-threonine dehydrogenase Mus musculus 0-3 21583527-1 2009 In the crystal structure of the title compound, C(16)H(19)N(4)O(2) (+) PF(6) (-), the cations and anions are situated on centres of inversion. Carbon 48-49 sperm associated antigen 17 Homo sapiens 71-76 19307313-8 2009 The association between the expression pattern of desatF-alpha and the chemical composition of cuticular hydrocarbons implies that the ancestral function of desatF-alpha is the second desaturation at the four carbons after the first double bond in diene synthesis, and the shift from bisexual to female-specific expression in desatF-alpha occurred in the ancestral lineage of Drosophila melanogaster subgroup. Carbon 110-117 Fad2 Drosophila melanogaster 50-62 19307313-8 2009 The association between the expression pattern of desatF-alpha and the chemical composition of cuticular hydrocarbons implies that the ancestral function of desatF-alpha is the second desaturation at the four carbons after the first double bond in diene synthesis, and the shift from bisexual to female-specific expression in desatF-alpha occurred in the ancestral lineage of Drosophila melanogaster subgroup. Carbon 110-117 Fad2 Drosophila melanogaster 157-169 19307313-8 2009 The association between the expression pattern of desatF-alpha and the chemical composition of cuticular hydrocarbons implies that the ancestral function of desatF-alpha is the second desaturation at the four carbons after the first double bond in diene synthesis, and the shift from bisexual to female-specific expression in desatF-alpha occurred in the ancestral lineage of Drosophila melanogaster subgroup. Carbon 110-117 Fad2 Drosophila melanogaster 157-169 19492820-3 2009 Sharp, gate-tunable resonances due to the bending mode of the nanotube are observed, combining resonance frequencies of up to nu(0) = 350 MHz with quality factors above Q = 10(5), much higher than previously reported results on suspended carbon nanotube resonators. Carbon 238-244 spen family transcriptional repressor Homo sapiens 0-5 19362711-2 2009 The success of this short and practical synthesis depends on the use of two key reactions: a stereoselective nucleophilic substitution at the anomeric position of 5 and 6, which allowed the construction of the gamma-lactone ring, and an alkyl substitution reaction on tosylated compound 4, which permitted the carbon chain elongation of the tetrahydrofuran ring appendage at C-6. Carbon 310-316 complement C6 Homo sapiens 375-378 19438286-2 2009 Electrochemical study of carbon-supported Pt-on-Pd heteronanostructures shows not only enhancement in electrocatalytic activity for oxygen reduction reaction (ORR) but also much improved stability in comparison to a commercial platinum catalyst (E-TEK, 20 wt % Pt, diameter: 2.5 nm). Carbon 25-31 TEK receptor tyrosine kinase Homo sapiens 248-251 19420667-0 2009 The structural characterization and H(2) sorption properties of carbon-supported Mg(1-x)Nix nanocrystallites. Carbon 64-70 BCL2 interacting protein 3 like Homo sapiens 88-91 19352533-1 2009 The fulvene complex (eta(6)-C(5)Me(4)CH(2))Re(C(6)F(5))(CO)(2) reacts at the exocyclic methylene carbon with potassium diphenylphosphide to yield the anionic species [(eta(5)-C(5)Me(4)CH(2)PPh(2))Re(C(6)F(5))(CO)(2)](-) (). Carbon 97-103 endothelin receptor type A Homo sapiens 21-24 19352533-1 2009 The fulvene complex (eta(6)-C(5)Me(4)CH(2))Re(C(6)F(5))(CO)(2) reacts at the exocyclic methylene carbon with potassium diphenylphosphide to yield the anionic species [(eta(5)-C(5)Me(4)CH(2)PPh(2))Re(C(6)F(5))(CO)(2)](-) (). Carbon 97-103 endothelin receptor type A Homo sapiens 168-171 19224916-4 2009 In addition, the one-carbon metabolism and purine biosynthesis transcriptional regulator Bas1p were strictly required for anaerobic growth on minimal medium, and this was similarly due to l-serine limitation in bas1 mutants. Carbon 21-27 Bas1p Saccharomyces cerevisiae S288C 89-94 19224916-4 2009 In addition, the one-carbon metabolism and purine biosynthesis transcriptional regulator Bas1p were strictly required for anaerobic growth on minimal medium, and this was similarly due to l-serine limitation in bas1 mutants. Carbon 21-27 Bas1p Saccharomyces cerevisiae S288C 211-215 19200561-0 2009 Assessment of the surface area occupied by molecules on activated carbon from liquid phase adsorption data from a combination of the BET and the Freundlich theories. Carbon 66-72 delta/notch like EGF repeat containing Homo sapiens 133-136 19200561-1 2009 A new equation is derived from a combination of the BET (Brunauer, Emmett, Teller) and Freundlich isotherms fitted for liquid phase adsorption data on activated carbons. Carbon 161-168 delta/notch like EGF repeat containing Homo sapiens 52-55 19185068-5 2009 Thioredoxin-mediated redox control appears to be a feature of the central pathways for assimilation and storage of carbon, sulphur and nitrogen, as well as for translation and protein folding. Carbon 115-121 thioredoxin H-type 1 Arabidopsis thaliana 0-11 19178276-3 2009 SPL is a member of the radical AdoMet superfamily of enzymes, and utilizes an iron-sulfur cluster and S-adenosylmethionine to repair SP by a direct reversal mechanism initiated by H atom abstraction from C-6 of the thymine dimer. Carbon 204-205 sphingosine-1-phosphate lyase 1 Homo sapiens 0-3 18786823-1 2009 This paper presents the integrated removal of carbon (measured as chemical oxygen demand i.e. COD) and NO(x)-N by sequentially adapted sludge, studied in an airlift reactor (ALR). Carbon 46-52 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 94-97 19033438-0 2009 Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. Carbon 74-80 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Mus musculus 0-6 23045014-4 2009 Like the cytochrome P450 system, PAH is able to oxidize both aliphatic and aromatic carbon centers in addition to undertaking the S-oxidation of aliphatic thioethers (including the two mucoactive drugs S-carboxymethyl-L-cysteine and S-methyl-L-cysteine). Carbon 84-90 phenylalanine hydroxylase Homo sapiens 33-36 18778729-6 2009 Recombinant salmon IFN-alpha1 and poly I:C proved to be potent inducers of IRF-7 in Atlantic salmon TO cells, and poly I:C also induced the gene in head kidney and liver of Atlantic salmon. Carbon 41-42 interferon regulatory factor 7 Salmo salar 75-80 18607531-3 2009 In terms of structural specificity, the methoxyl group on C-5 and C-7 and the short alkyl chain (1-5 carbons) on C-6 may be essential for the potent activities. Carbon 101-108 complement component 6 Mus musculus 113-116 19888214-1 2009 Highly conserved among eukaryotic cells, the AMP-activated kinase (AMPK) is a central regulator of carbon metabolism. Carbon 99-105 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 67-71 18974051-5 2008 Structure-function studies indicate that the carboxylic acid moiety, nitration at the 9 or 10 olefinic carbon, and unsaturation is required for XOR inhibition. Carbon 103-109 xanthine dehydrogenase Homo sapiens 144-147 20641737-0 2004 Gd@C82 Fullerenol Fullerenes, also known as buckyballs, are spheroidal carbon cages with a molecular formula of C2n (n = 30-41) and a diameter of ~1 nm (1). Carbon 71-77 complement C8 beta chain Homo sapiens 3-6 18588327-2 2008 Nitrogen adsorption measurement interpreted by BET, DR, HK, and NLDFT methods reveals these nanostructured activated carbons exhibit a high surface area of up to 4000 m2/g, a micropore volume up to approximately 1.75 mL/g, and an average pore size of approximately 10-20 angstroms. Carbon 117-124 delta/notch like EGF repeat containing Homo sapiens 47-50 18803346-4 2008 The overlapping occurs as a result of the additions made to the carbonyl carbon (C-8/C-11) of the cage. Carbon 64-70 homeobox C8 Homo sapiens 81-89 18534653-8 2008 We found that NADPH oxidase null mice responded to SWCNT exposure with a marked accumulation of PMNs and elevated levels of apoptotic cells in the lungs, production of pro-inflammatory cytokines, decreased production of the anti-inflammatory and pro-fibrotic cytokine, TGF-beta, and significantly lower levels of collagen deposition, as compared to C57BL/6 control mice. Carbon 51-56 transforming growth factor, beta 1 Mus musculus 269-277 18507803-9 2008 Starch content and a ratio of carbon to nitrogen were higher in aox1a than in WT. Carbon 30-36 alternative oxidase 1A Arabidopsis thaliana 64-69 18507803-10 2008 Our results indicate that a lack of AOX was linked to a difference in the carbon and nitrogen balance, and an up-regulation of the transcription of antioxidant defence system at low temperature. Carbon 74-80 alternative oxidase 2 Arabidopsis thaliana 36-39 18585294-5 2008 Dissolved organic carbon, chloride and iodide ions are tolerated in concentrations of 15 mg DOC l(-1), >21 g Cl(-)l(-1), and 10 mg I(-)l(-1). Carbon 18-24 collectin subfamily member 10 Homo sapiens 112-121 21694376-1 2008 Semiconducting single-walled carbon nanotubes resonantly excited by the interband E(22)(S) electronic transitions (at 1064 nm) display for the two components of the radial Raman band-one associated with the isolated tubes and the other associated with the bundled tubes-an anti-Stokes/Stokes Raman intensity ratio (I(aS)/I(S)) which deviates oppositely from the predictions of the Maxwell-Boltzmann formula. Carbon 29-35 transcription factor 4 Homo sapiens 82-87 17428604-4 2008 The proper choice of the preparation conditions allows to produce microporous activated carbon with a micropore volume up to 0.492 cm(3)/g and a BET surface area of 1260 m(2)/g. Carbon 88-94 delta/notch like EGF repeat containing Homo sapiens 145-148 18570516-1 2008 Carbon 1s shake-up spectra of fullerenes C(60), C(70), and C(82) and single-walled carbon nanotubes (SWCNTs) of (5,5), (6,5), and (7,6) have been investigated by using equivalent core hole Kohn-Sham density functional theory approach, in which only one-electron transition between molecular orbitals within core-hole potential is considered. Carbon 0-1 complement C8 beta chain Homo sapiens 59-64 18570516-3 2008 Calculations have also been performed for endohedral metallofullerene Gd@C(82) to demonstrate the possible use of shake-up processes to identify the charge transfer between the metal ion and the carbon cage. Carbon 195-201 complement C8 beta chain Homo sapiens 73-78 18508265-1 2008 An immobilized Staurosporine aglycone isostere where one of the indole nitrogen atoms was replaced by carbon has been sequentially functionalized to generate compounds inhibiting TrkA kinase. Carbon 102-108 neurotrophic receptor tyrosine kinase 1 Homo sapiens 179-183 18338327-4 2008 It is shown that the (13)C resonances of C-6, C-7 and C-11 carbon atoms are suitable for distinguishing between the tautomeric forms of aza-derivatives of gossypol in the solid state. Carbon 25-26 complement C6 Homo sapiens 41-44 18417639-3 2008 In a screen for genes whose expression was altered in response to the induction of AP3 activity, we identified GNC (GATA, nitrate-inducible, carbon-metabolism-involved) as being negatively regulated by AP3 and PI. Carbon 141-147 K-box region and MADS-box transcription factor family protein Arabidopsis thaliana 83-86 18417639-3 2008 In a screen for genes whose expression was altered in response to the induction of AP3 activity, we identified GNC (GATA, nitrate-inducible, carbon-metabolism-involved) as being negatively regulated by AP3 and PI. Carbon 141-147 K-box region and MADS-box transcription factor family protein Arabidopsis thaliana 202-205 18452327-6 2008 In double and multiple H-bond forms, H-bonding effects at individual sites are basically additive, and complexes in which the C=O and the OH hydrogen are simultaneously H bonded exhibit significantly low nuC=O frequencies at 1725-1700 cm(-1), while complexes H bonded at the oxygen of the COH in addition to either at the C=O or the OH hydrogen exhibit medium frequencies of 1740-1765 cm(-1). Carbon 126-127 nucleobindin 1 Homo sapiens 204-207 18375835-6 2008 The length of the carbon chain of the fatty acid species defines the substrate specificity for the different acyl-CoA synthetases (ACS). Carbon 18-24 acyl-CoA synthetase short chain family member 2 Homo sapiens 109-129 18375835-6 2008 The length of the carbon chain of the fatty acid species defines the substrate specificity for the different acyl-CoA synthetases (ACS). Carbon 18-24 acyl-CoA synthetase short chain family member 2 Homo sapiens 131-134 18375835-8 2008 The purpose of this review is to report on the large family of mammalian long-chain acyl-CoA synthetases (ACSL), which activate fatty acids with chain lengths of 12 to 20 carbon atoms. Carbon 171-177 acyl-CoA synthetase short chain family member 2 Homo sapiens 84-104 17669408-9 2008 Treatment of FTEC with TLR3 agonist poly(I:C) resulted in increased expression of interleukin-8, tumor-necrosis factor alpha, human beta-defensin 2, interferon beta, and interferon stimulated genes myxovirus resistance gene 1, 2",5"-oligoadenylate synthetase, and protein kinase R. Additionally, FTEC exposed to poly(I:C) also resulted in the induction of TLR2, TLR3, and TLR7. Carbon 16-17 toll like receptor 3 Homo sapiens 23-27 17669408-9 2008 Treatment of FTEC with TLR3 agonist poly(I:C) resulted in increased expression of interleukin-8, tumor-necrosis factor alpha, human beta-defensin 2, interferon beta, and interferon stimulated genes myxovirus resistance gene 1, 2",5"-oligoadenylate synthetase, and protein kinase R. Additionally, FTEC exposed to poly(I:C) also resulted in the induction of TLR2, TLR3, and TLR7. Carbon 16-17 interferon beta 1 Homo sapiens 149-164 17669408-9 2008 Treatment of FTEC with TLR3 agonist poly(I:C) resulted in increased expression of interleukin-8, tumor-necrosis factor alpha, human beta-defensin 2, interferon beta, and interferon stimulated genes myxovirus resistance gene 1, 2",5"-oligoadenylate synthetase, and protein kinase R. Additionally, FTEC exposed to poly(I:C) also resulted in the induction of TLR2, TLR3, and TLR7. Carbon 16-17 toll like receptor 3 Homo sapiens 362-366 18347047-3 2008 Deletion of ccpA, coding for the catabolite control protein A (CcpA), which regulates gene expression in response to the carbon source, abolished the capacity of SA113 to form a biofilm under static and flow conditions, while still allowing primary attachment to polystyrene surfaces. Carbon 121-127 AT695_RS08815 Staphylococcus aureus 12-16 18347047-3 2008 Deletion of ccpA, coding for the catabolite control protein A (CcpA), which regulates gene expression in response to the carbon source, abolished the capacity of SA113 to form a biofilm under static and flow conditions, while still allowing primary attachment to polystyrene surfaces. Carbon 121-127 AT695_RS08815 Staphylococcus aureus 33-61 18347047-3 2008 Deletion of ccpA, coding for the catabolite control protein A (CcpA), which regulates gene expression in response to the carbon source, abolished the capacity of SA113 to form a biofilm under static and flow conditions, while still allowing primary attachment to polystyrene surfaces. Carbon 121-127 AT695_RS08815 Staphylococcus aureus 63-67 18405332-12 2008 A possible role for CAH8 in the inorganic carbon acquisition by C. reinhardtii is discussed. Carbon 42-48 uncharacterized protein Chlamydomonas reinhardtii 20-24 18023379-5 2008 Molecular dynamics simulations clearly showed that the configuration of the distal carbon C6 of l,l-DAP is critical for complex formation since both amino and carboxylate groups are involved in Hbonding interactions with the active site residues. Carbon 83-89 death associated protein Homo sapiens 100-103 21817664-0 2008 The structure and function of ribonuclease A upon interacting with carbon nanotubes. Carbon 67-73 ribonuclease A family member 1, pancreatic Homo sapiens 30-44 21817664-2 2008 Our studies showed that multi-walled carbon nanotubes and single-walled carbon nanotubes functionalized with carboxylic groups interacted with ribonuclease A (RNase A) and caused the reduction of its activity by changing its conformation, thus protecting RNA from enzymatic cleavage. Carbon 37-43 ribonuclease A family member 1, pancreatic Homo sapiens 143-157 21817664-2 2008 Our studies showed that multi-walled carbon nanotubes and single-walled carbon nanotubes functionalized with carboxylic groups interacted with ribonuclease A (RNase A) and caused the reduction of its activity by changing its conformation, thus protecting RNA from enzymatic cleavage. Carbon 37-43 ribonuclease A family member 1, pancreatic Homo sapiens 159-166 21817664-2 2008 Our studies showed that multi-walled carbon nanotubes and single-walled carbon nanotubes functionalized with carboxylic groups interacted with ribonuclease A (RNase A) and caused the reduction of its activity by changing its conformation, thus protecting RNA from enzymatic cleavage. Carbon 72-78 ribonuclease A family member 1, pancreatic Homo sapiens 143-157 21817664-2 2008 Our studies showed that multi-walled carbon nanotubes and single-walled carbon nanotubes functionalized with carboxylic groups interacted with ribonuclease A (RNase A) and caused the reduction of its activity by changing its conformation, thus protecting RNA from enzymatic cleavage. Carbon 72-78 ribonuclease A family member 1, pancreatic Homo sapiens 159-166 21817664-3 2008 The results showed that RNase A was less active on the carbon nanotube surface than in free solution, and the activity was decreased further on larger carbon nanotubes, suggesting that carbon nanotubes with various surface modifications may be useful in RNA extraction, purification, and manipulation. Carbon 55-61 ribonuclease A family member 1, pancreatic Homo sapiens 24-31 18344607-2 2008 When expressed in Xenopus oocytes, mOat2-mediated [(3)H]PGE(2) transport was inhibited by three- to five-carbon SCFAs (C3 to C5). Carbon 105-111 solute carrier family 22 (organic anion transporter), member 7 Mus musculus 35-40 18287036-1 2008 Analysis of the x-ray crystal structure of mono-substituted acetylenic thienopyrimidine 6 complexed with the ErbB family enzyme ErbB-4 revealed a covalent bond between the terminal carbon of the acetylene moiety and the sulfhydryl group of Cys-803 at the solvent interface. Carbon 181-187 erb-b2 receptor tyrosine kinase 4 Homo sapiens 128-134 18323114-8 2008 Biodegradation of EDB in the source microcosms was confirmed by carbon specific isotope analysis, with a delta13C enrichment factor of -5.6 per thousand. Carbon 64-70 vesicle associated membrane protein 8 Homo sapiens 18-21 18000030-3 2008 However, in light of the recent discovery that the nociceptor-specific ion channel transient receptor potential A1 (TRPA1) can be activated by exogenous electrophilic irritants through direct covalent modification, we reasoned that electrophilic carbon-containing A- and J-series prostaglandins, metabolites of prostaglandins (PG) E(2) and D(2), respectively, would excite nociceptive neurons through direct activation of TRPA1. Carbon 246-252 transient receptor potential cation channel subfamily A member 1 Homo sapiens 83-114 18000030-3 2008 However, in light of the recent discovery that the nociceptor-specific ion channel transient receptor potential A1 (TRPA1) can be activated by exogenous electrophilic irritants through direct covalent modification, we reasoned that electrophilic carbon-containing A- and J-series prostaglandins, metabolites of prostaglandins (PG) E(2) and D(2), respectively, would excite nociceptive neurons through direct activation of TRPA1. Carbon 246-252 transient receptor potential cation channel subfamily A member 1 Homo sapiens 116-121 18000030-3 2008 However, in light of the recent discovery that the nociceptor-specific ion channel transient receptor potential A1 (TRPA1) can be activated by exogenous electrophilic irritants through direct covalent modification, we reasoned that electrophilic carbon-containing A- and J-series prostaglandins, metabolites of prostaglandins (PG) E(2) and D(2), respectively, would excite nociceptive neurons through direct activation of TRPA1. Carbon 246-252 transient receptor potential cation channel subfamily A member 1 Homo sapiens 422-427 18032102-2 2007 To verify the metabolic phenotype predications for increasing ethanol formation, two engineered S. cerevisiae KAM-14, KAM-15 strains were constructed for possible redirection of glycerol carbon flux into ethanol by overexpression of GLT1 in the fps1DeltagpdDelta mutant. Carbon 187-193 glutamate synthase (NADH) Saccharomyces cerevisiae S288C 233-237 17955129-12 2007 The generation of TiS(2), SnS(2) and SnS in this way are very rare examples of metal sulfide deposition from C-S bond fission within a thioether complex. Carbon 109-110 sodium voltage-gated channel alpha subunit 11 Homo sapiens 26-32 17823126-11 2007 These findings demonstrate that a normal rate of flux of glucose carbons through CL and FAS is not required for GSIS in insulinoma cell lines or rat islets. Carbon 65-72 ATP citrate lyase Rattus norvegicus 81-83 17691719-10 2007 It is observed that, in all nut-fullerene graphs found so far, occupation of the NBO would require the fullerene to carry at least 3 negative charges, whereas in most carbon cages based on small nut cubic polyhedra, the NBO would be the highest occupied molecular orbital (HOMO) for the uncharged system. Carbon 167-173 NUT midline carcinoma family member 1 Homo sapiens 28-31 17691719-10 2007 It is observed that, in all nut-fullerene graphs found so far, occupation of the NBO would require the fullerene to carry at least 3 negative charges, whereas in most carbon cages based on small nut cubic polyhedra, the NBO would be the highest occupied molecular orbital (HOMO) for the uncharged system. Carbon 167-173 NUT midline carcinoma family member 1 Homo sapiens 195-198 17658804-1 2007 Carbon nanomaterials, including herringbone graphite carbon nanofibers (GNFH), multiwalled carbon nanotubes (MWCNT), and carbon black, were surface-modified by a new poly(vinylpyrrolidone) (PVP) grafting process as well as by the conventional acid-oxidation (AO) process, and characterized by FTIR, TGA, Raman, HRTEM, XRD, and XPS measurements. Carbon 0-6 T-box transcription factor 1 Homo sapiens 299-302 17533128-2 2007 Three 9,10-di-O-(-)-camphanoyl-7,8,9,10-tetrahydro-benzo[h]chromen-2-one (7-carbon-DCK) analogs (3a-c) were synthesized and evaluated for inhibition of HIV-1 replication in H9 lymphocytes. Carbon 76-82 deoxycytidine kinase Homo sapiens 83-86 17533128-3 2007 All three new carbon bioisosteres of the anti-HIV lead DCK showed anti-HIV activity. Carbon 14-20 deoxycytidine kinase Homo sapiens 55-58 17563821-1 2007 A simple and highly efficient method for the selective reduction of the C=C bond in allylic alcohols has been developed using the ruthenium(II) catalyst [{RuCl(mu-Cl)(eta(6)-C(6)Me(6)}2]. Carbon 72-73 endothelin receptor type A Homo sapiens 167-170 17563821-1 2007 A simple and highly efficient method for the selective reduction of the C=C bond in allylic alcohols has been developed using the ruthenium(II) catalyst [{RuCl(mu-Cl)(eta(6)-C(6)Me(6)}2]. Carbon 74-75 endothelin receptor type A Homo sapiens 167-170 17654947-11 2007 The TGA measurements, carried out under argon flow, show that the dominant weight loss of the sample occurs in the temperature range 400-600 degrees C corresponding to the removal of the impurities and amorphous carbon. Carbon 212-218 T-box transcription factor 1 Homo sapiens 4-7 17568546-2 2007 The amounts of matrix metalloproteinase 13 (MMP-13) mRNA in osteoblast-like MC3T3-E1 cells tended to decrease after carbon ion irradiation. Carbon 116-122 matrix metallopeptidase 13 Mus musculus 15-42 17568546-2 2007 The amounts of matrix metalloproteinase 13 (MMP-13) mRNA in osteoblast-like MC3T3-E1 cells tended to decrease after carbon ion irradiation. Carbon 116-122 matrix metallopeptidase 13 Mus musculus 44-50 17175156-2 2007 The biosensor is based on the activity of glucose dehydrogenase (GDH) and diaphorase (DI) co-immobilized with NAD(+) into a carbon nanotube paste (CNTP) electrode modified with an osmium functionalized polymer. Carbon 124-130 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 42-63 17175156-2 2007 The biosensor is based on the activity of glucose dehydrogenase (GDH) and diaphorase (DI) co-immobilized with NAD(+) into a carbon nanotube paste (CNTP) electrode modified with an osmium functionalized polymer. Carbon 124-130 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 65-68 17175156-2 2007 The biosensor is based on the activity of glucose dehydrogenase (GDH) and diaphorase (DI) co-immobilized with NAD(+) into a carbon nanotube paste (CNTP) electrode modified with an osmium functionalized polymer. Carbon 124-130 dihydrolipoamide dehydrogenase Homo sapiens 74-84 17175156-2 2007 The biosensor is based on the activity of glucose dehydrogenase (GDH) and diaphorase (DI) co-immobilized with NAD(+) into a carbon nanotube paste (CNTP) electrode modified with an osmium functionalized polymer. Carbon 124-130 dihydrolipoamide dehydrogenase Homo sapiens 86-88 17485826-4 2007 This conversion was found to be an efficient method for the preparation of carboxylic acids (Cn) to one-carbon degraded aldehydes (Cn-1) via 2-hydroperoxy acids. Carbon 104-110 5'-nucleotidase, cytosolic IA Homo sapiens 131-135 17988014-5 2007 Calixarenes C-97 and C-99 (100 microM), which have similar structure, have monodirectional influence on activity of three functionally different Mg2+-dependent ATPases of the myometrium: actomyosin ATPase and two ATPases, that related to the ATP-hydrolases of P-type--Ca2+, Mg2+ -ATPase and Na+, K+ -ATPase of plasmatic membranes. Carbon 0-1 dynein axonemal heavy chain 8 Homo sapiens 160-166 17988014-5 2007 Calixarenes C-97 and C-99 (100 microM), which have similar structure, have monodirectional influence on activity of three functionally different Mg2+-dependent ATPases of the myometrium: actomyosin ATPase and two ATPases, that related to the ATP-hydrolases of P-type--Ca2+, Mg2+ -ATPase and Na+, K+ -ATPase of plasmatic membranes. Carbon 0-1 dynein axonemal heavy chain 8 Homo sapiens 198-204 17988014-5 2007 Calixarenes C-97 and C-99 (100 microM), which have similar structure, have monodirectional influence on activity of three functionally different Mg2+-dependent ATPases of the myometrium: actomyosin ATPase and two ATPases, that related to the ATP-hydrolases of P-type--Ca2+, Mg2+ -ATPase and Na+, K+ -ATPase of plasmatic membranes. Carbon 0-1 dynein axonemal heavy chain 8 Homo sapiens 198-204 17331505-0 2007 Carbon inhibits vascular endothelial growth factor- and fibroblast growth factor-promoted angiogenesis. Carbon 0-6 vascular endothelial growth factor A Gallus gallus 16-50 17331505-4 2007 Herein, we studied the anti-angiogenic effects of various carbon materials such as graphite, multiwalled carbon nanotubes and fullerenes in vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (FGF2)-induced angiogenesis evaluated in the chick chorioallantoic membrane (CAM) model. Carbon 58-64 vascular endothelial growth factor A Gallus gallus 140-174 17331505-4 2007 Herein, we studied the anti-angiogenic effects of various carbon materials such as graphite, multiwalled carbon nanotubes and fullerenes in vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (FGF2)-induced angiogenesis evaluated in the chick chorioallantoic membrane (CAM) model. Carbon 58-64 vascular endothelial growth factor A Gallus gallus 176-180 17331505-4 2007 Herein, we studied the anti-angiogenic effects of various carbon materials such as graphite, multiwalled carbon nanotubes and fullerenes in vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (FGF2)-induced angiogenesis evaluated in the chick chorioallantoic membrane (CAM) model. Carbon 105-111 vascular endothelial growth factor A Gallus gallus 140-174 16876939-5 2007 The adsorption capabilities of different activated carbon generally followed their pH(zpc) values. Carbon 51-57 zona pellucida glycoprotein 3 Homo sapiens 86-89 16876939-6 2007 Activated carbons with higher pH(zpc) values exhibit a neutral or positive charge under typical pH conditions, promoting m-LR adsorption on the carbon surface. Carbon 10-17 zona pellucida glycoprotein 3 Homo sapiens 33-36 16876939-6 2007 Activated carbons with higher pH(zpc) values exhibit a neutral or positive charge under typical pH conditions, promoting m-LR adsorption on the carbon surface. Carbon 10-16 zona pellucida glycoprotein 3 Homo sapiens 33-36 16920014-7 2007 OLE1 is regulated through Spt23p and Mga2p by multiple systems that control its transcription and mRNA stability in response to diverse stimuli that include nutrient fatty acids, carbon source, metal ions and the availability of oxygen. Carbon 179-185 Mga2p Saccharomyces cerevisiae S288C 37-42 17180337-1 2007 A novel type of glassy carbon electrode modified with magnetic carbon-coated nickel nanoparticles (C-Ni/GCE) was fabricated and the electrochemical properties of brucine were studied using it. Carbon 23-29 5'-nucleotidase, cytosolic IA Homo sapiens 99-107 17180337-1 2007 A novel type of glassy carbon electrode modified with magnetic carbon-coated nickel nanoparticles (C-Ni/GCE) was fabricated and the electrochemical properties of brucine were studied using it. Carbon 63-69 5'-nucleotidase, cytosolic IA Homo sapiens 99-107 17268030-13 2007 PTH treatment increased calvarial uptake of 64Cu-CB-TE2A-c(RGDyK), compared with uptake in mice receiving a sham treatment. Carbon 16-17 parathyroid hormone Mus musculus 0-3 17937376-3 2007 The affinity complexes of glucose dehydrogenase (GDH) with the NADP(+) cofactor or alcohol dehydrogenase (AlcDH) with the NAD(+) cofactor were crosslinked with glutaric dialdehyde and the biomolecule-functionalized SWCNT materials were deposited on glassy carbon electrodes. Carbon 215-220 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 26-47 17937376-3 2007 The affinity complexes of glucose dehydrogenase (GDH) with the NADP(+) cofactor or alcohol dehydrogenase (AlcDH) with the NAD(+) cofactor were crosslinked with glutaric dialdehyde and the biomolecule-functionalized SWCNT materials were deposited on glassy carbon electrodes. Carbon 215-220 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 49-52 17937376-3 2007 The affinity complexes of glucose dehydrogenase (GDH) with the NADP(+) cofactor or alcohol dehydrogenase (AlcDH) with the NAD(+) cofactor were crosslinked with glutaric dialdehyde and the biomolecule-functionalized SWCNT materials were deposited on glassy carbon electrodes. Carbon 256-262 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 26-47 17937376-3 2007 The affinity complexes of glucose dehydrogenase (GDH) with the NADP(+) cofactor or alcohol dehydrogenase (AlcDH) with the NAD(+) cofactor were crosslinked with glutaric dialdehyde and the biomolecule-functionalized SWCNT materials were deposited on glassy carbon electrodes. Carbon 256-262 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 49-52 17990247-1 2007 Compound-specific stable carbon isotope analysis of amino acids by gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS) is a highly selective and sensitive method for probing the biosynthetic/diagenetic pathways, pool size and turnover rates of proteins, previously intractable to bulk isotope analyses. Carbon 25-31 guanylate cyclase 2C Homo sapiens 130-134 17096314-3 2006 In this work, electrode sizes and spacings were optimized to result in dual carbon electrodes that are 1 microm in height and separated by 100 microm. Carbon 76-82 VPS52 subunit of GARP complex Homo sapiens 99-104 16982622-7 2006 The contribution of AtECH2 to the degradation of unsaturated fatty acids was assessed by analyzing the carbon flux through the beta-oxidation cycle in plants that synthesize peroxisomal polyhydroxyalkanoate and that were over- or underexpressing the AtECH2 gene. Carbon 103-109 enoyl-CoA hydratase 2 Arabidopsis thaliana 20-26 16982622-8 2006 These studies revealed that AtECH2 participates in vivo to the conversion of the intermediate 3R-hydroxyacyl-CoA, generated by the metabolism of fatty acids with a cis (Z)-unsaturated bond on an even-numbered carbon, to the 2E-enoyl-CoA for further degradation through the core beta-oxidation cycle. Carbon 209-215 enoyl-CoA hydratase 2 Arabidopsis thaliana 28-34 16997316-1 2006 Activated carbon with BET surface areas in a narrow range from 2318 to 2474 m2/g was made by soaking the char made from corncob in a concentrated NaOH solution at NaOH/char ratios from 3 to 6; the mesopore volumes of the activated carbon were significantly changed from 21 to 58%. Carbon 10-16 delta/notch like EGF repeat containing Homo sapiens 22-25 17393837-3 2006 It is created in the .Net framework with C# for Windows and in the Carbon framework for Mac OS X. Carbon 67-73 Sp7 transcription factor Homo sapiens 92-96 17138693-0 2006 C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis. Carbon 0-1 Cytochrome P450 superfamily protein Arabidopsis thaliana 34-41 16854981-5 2006 Analysis of binding energies between Fui1p and different Urd analogs indicated that Fuip1 interacted with C(3")-OH, C(2")-OH, C(5)-H, and N(3)-H of Urd. Carbon 106-107 uridine permease Saccharomyces cerevisiae S288C 37-42 16872648-3 2006 These P450s show high homology with Arabidopsis CYP734A1/BAS1 (formerly CYP72B1), which inactivates BRs via C-26 hydroxylation. Carbon 48-49 Cytochrome P450 superfamily protein Arabidopsis thaliana 57-61 16872648-3 2006 These P450s show high homology with Arabidopsis CYP734A1/BAS1 (formerly CYP72B1), which inactivates BRs via C-26 hydroxylation. Carbon 48-49 Cytochrome P450 superfamily protein Arabidopsis thaliana 72-79 16488539-2 2006 The activated cane pith carbons, with KOH/char ratios of 2-6, exhibited BET surface areas ranging from 912 to 2299 m(2) g(-1). Carbon 24-31 delta/notch like EGF repeat containing Homo sapiens 72-75 16524933-10 2006 CONCLUSIONS: Our results indicate that serum cystatin C is a reliable marker of GFR in patients with mildly to moderately impaired kidney function and has a higher diagnostic accuracy than serum creatinine and calculated creatinine clearance from the C&G formula in female patients. Carbon 251-253 cystatin C Homo sapiens 45-55 16399790-9 2006 Pretreatment with wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase, was able to abate the effect of DE(as) on poly(I:C)-induced IFN-beta expression. Carbon 134-135 interferon beta 1 Homo sapiens 145-153 16432629-6 2006 Analysis of MAM gene family in both species, which also include genes controlling 4-carbon side-chain GSL, separated the genes in two groups based on exon numbers and function. Carbon 84-90 methylthioalkylmalate synthase 1 Arabidopsis thaliana 12-15 16683774-1 2006 We developed a polymer coating for carbon nanotubes (CNTs) that mimics the mucin glycoprotein coating of mammalian cells. Carbon 35-41 LOC100508689 Homo sapiens 75-80 16406095-7 2006 Histamine and poly (I:C), a specific TLR3 ligand stimulated interleukin (IL)-8 secretion from both cell types. Carbon 22-23 toll like receptor 3 Homo sapiens 37-41 16610787-6 2006 Transformation of the C=O functionality at position 4 into a C=S group provided 5,7-dihydroxy-3-(4-hydroxyphenyl)-4(3H)-quinazolinethione (1ba), which acts as an agonist on both ER subtypes but has 56-fold higher binding affinity for ERbeta over ERalpha [IC(50)(ERbeta) = 47 nM] and 215-fold higher potency in the transcription assay [EC(50)(ERbeta) = 13 nM]. Carbon 22-23 estrogen receptor 2 Homo sapiens 234-240 16610787-6 2006 Transformation of the C=O functionality at position 4 into a C=S group provided 5,7-dihydroxy-3-(4-hydroxyphenyl)-4(3H)-quinazolinethione (1ba), which acts as an agonist on both ER subtypes but has 56-fold higher binding affinity for ERbeta over ERalpha [IC(50)(ERbeta) = 47 nM] and 215-fold higher potency in the transcription assay [EC(50)(ERbeta) = 13 nM]. Carbon 22-23 estrogen receptor 2 Homo sapiens 262-268 16610787-6 2006 Transformation of the C=O functionality at position 4 into a C=S group provided 5,7-dihydroxy-3-(4-hydroxyphenyl)-4(3H)-quinazolinethione (1ba), which acts as an agonist on both ER subtypes but has 56-fold higher binding affinity for ERbeta over ERalpha [IC(50)(ERbeta) = 47 nM] and 215-fold higher potency in the transcription assay [EC(50)(ERbeta) = 13 nM]. Carbon 22-23 estrogen receptor 2 Homo sapiens 262-268 18407618-1 2008 A novel electrochemical cytosensing strategy was designed based on the specific recognition of integrin receptors on a cell surface to arginine-glycine-aspartic acid-serine (RGDS)-functionalized single-walled carbon nanotubes (SWNTs). Carbon 209-215 ral guanine nucleotide dissociation stimulator Homo sapiens 174-178 18473419-9 2008 To further explore the mechanism of rosiglitazone action, we found that rosiglitazone can significantly increase the expression of PPAR gamma [E: -18.212 +/- (-3.909) vs B: -27.315 +/- (-6.348) and C: -25.647 +/- (-5.694), P < 0.05], reduce the NF-kappaB binding activity (E: 88.89 +/- 19.34 vs B: 141.11 +/- 15.37, C: 112.89 +/- 20.17 and D: 108.89 +/- 20.47, P < 0.05), and lower the serum level of TNF-alpha (E: 1.613 +/- 0.420 ng/mL vs B: 2.892 +/- 0.587 ng/mL, C: 2.346 +/- 0.371 ng/mL and D: 2.160 +/- 0.395 ng/mL, P < 0.05) and IL-6 (E: 0.106 +/- 0.021 ng/mL vs B: 0.140 +/- 0.031 ng/mL and C: 0.137 +/- 0.027 ng/mL, P < 0.05) in mice with liver fibrosis. Carbon 198-199 peroxisome proliferator activated receptor gamma Mus musculus 131-141 21202271-2 2008 In the crystal structure, inter-molecular C-H O and O-H O hydrogen bonds and C-Cl O close contacts [Cl O = 3.0123 (13) A and C-Cl O = 171.14 (7) ] link the mol-ecules, generating R(2) (2)(16), R(4) (2)(19) and R(4) (4)(22) ring motifs by C(6) chains to form a three-dimensional network. Carbon 42-43 CD1a molecule Homo sapiens 193-197 21202271-2 2008 In the crystal structure, inter-molecular C-H O and O-H O hydrogen bonds and C-Cl O close contacts [Cl O = 3.0123 (13) A and C-Cl O = 171.14 (7) ] link the mol-ecules, generating R(2) (2)(16), R(4) (2)(19) and R(4) (4)(22) ring motifs by C(6) chains to form a three-dimensional network. Carbon 42-43 CD1a molecule Homo sapiens 210-214 21202271-2 2008 In the crystal structure, inter-molecular C-H O and O-H O hydrogen bonds and C-Cl O close contacts [Cl O = 3.0123 (13) A and C-Cl O = 171.14 (7) ] link the mol-ecules, generating R(2) (2)(16), R(4) (2)(19) and R(4) (4)(22) ring motifs by C(6) chains to form a three-dimensional network. Carbon 77-78 CD1a molecule Homo sapiens 193-197 21202271-2 2008 In the crystal structure, inter-molecular C-H O and O-H O hydrogen bonds and C-Cl O close contacts [Cl O = 3.0123 (13) A and C-Cl O = 171.14 (7) ] link the mol-ecules, generating R(2) (2)(16), R(4) (2)(19) and R(4) (4)(22) ring motifs by C(6) chains to form a three-dimensional network. Carbon 77-78 CD1a molecule Homo sapiens 210-214 16394182-4 2006 Aromatic iodination meta to the phenolic hydroxyl (on the 6"-carbon atom) converts arvanil and olvanil from TRPV1 agonists into antagonists. Carbon 61-67 transient receptor potential cation channel subfamily V member 1 Homo sapiens 108-113 16533058-4 2006 Like ionizing radiation (IR) and other radiomimetics, breaks induced by C-1027 efficiently activate ATM by phosphorylation at Ser1981, yet unlike other radiomimetics and IR, DNA breaks induced by C-1027 result in normal phosphorylation of p53 and the cell cycle checkpoint kinases (Chk1 and Chk2) in the absence of ATM. Carbon 72-73 checkpoint kinase 2 Homo sapiens 291-295 27782270-2 2016 In this way, bone morphogenetic protein (BMP)-2, fibronectin, and platelet-rich plasma (PRP) could be immobilized on parylene-C surfaces. Carbon 126-127 bone morphogenetic protein 2 Homo sapiens 13-47 16406276-7 2006 H2BC almost exclusively correlates protons and proton-bearing carbon spins separated by two covalent bonds and is independent of occasionally vanishing (2)J(CH) coupling constants, which alleviates the problem of missing two-bond correlations in HMBC spectra. Carbon 62-68 H2B clustered histone 13 Homo sapiens 0-4 18281401-4 2008 HPr and EIIA regulate carbon utilization in other bacteria. Carbon 22-28 haptoglobin-related protein Homo sapiens 0-3 18281401-5 2008 hpr and manX in-frame deletion mutants exhibited altered carbon metabolism and other phenotypes. Carbon 57-63 haptoglobin-related protein Homo sapiens 0-3 18281401-10 2008 The results show that HPr and ManX (EIIA(Man)) are involved in more than carbon regulation in S. meliloti and suggest that the phenotypes observed occur due to activity of HPr or one of its phosphorylated forms. Carbon 73-79 haptoglobin-related protein Homo sapiens 22-25 18211105-4 2008 The functionalized carbons were characterized by elemental analysis, X-ray photoelectron spectroscopy (XPS), and nitrogen adsorption isotherms using the BET isotherm and DFT Monte Carlo simulations. Carbon 19-26 delta/notch like EGF repeat containing Homo sapiens 153-156 16361229-3 2006 Moreover, we provide evidence that Glc7-Reg1 phosphatase acts as an upstream activator of Yck1,2 kinases in a novel signaling pathway that modulates kinase activity in response to carbon source availability. Carbon 180-186 type 1 serine/threonine-protein phosphatase catalytic subunit GLC7 Saccharomyces cerevisiae S288C 35-39 27642711-2 2016 To this end, a formate metal-organic framework and activated carbon fiber composite was synthesized in our work by a simple two-step process, involving homogeneous precipitation of a MOF precursor on an activated carbon fiber and subsequent template replication. Carbon 61-67 lysine acetyltransferase 8 Homo sapiens 183-186 16111690-4 2006 Fir-wood carbon activated with CO2 gasification from 0 to 60 min exhibited a BET surface area ranging from 1371 to 2821 m2 g(-1), with a pore volume significantly increased from 0.81 to 1.73 m2 g(-1). Carbon 9-15 delta/notch like EGF repeat containing Homo sapiens 77-80 16470264-3 2006 The PAH, the Forties crude and diesel oil equivalent concentrations were generally higher in sediment of fine grain size and higher organic carbon concentration. Carbon 140-146 phenylalanine hydroxylase Homo sapiens 4-7 27642711-2 2016 To this end, a formate metal-organic framework and activated carbon fiber composite was synthesized in our work by a simple two-step process, involving homogeneous precipitation of a MOF precursor on an activated carbon fiber and subsequent template replication. Carbon 213-219 lysine acetyltransferase 8 Homo sapiens 183-186 18785516-8 2008 Compared with that of the control group, dC2/DV [B:(17 +/-5)%/L, C: (13 +/-4)%/L] showed a decrease (t = -11.82, -16.75, all P < 0.01) and dC3/DV [B:(3.2 +/- 0.8)%/L, C:(4.1 +/-1.2)%/L] and SR23 [B:(17.2 +/- 3.5)%, C:(28.3 +/- 6.9)%] showed an increase (t = 2. Carbon 0-1 anon-17Cc Drosophila melanogaster 142-148 26470640-4 2016 Here, we used two uracil-N-glycosylase (UNG1) mutants, Y147A or N204D, to generate AP sites directly in the mtDNA of NIH3T3 cells in vivo at sites normally occupied by T or C residues, respectively, and to study repair of these lesions in their native context. Carbon 173-174 uracil DNA glycosylase Mus musculus 40-44 18197643-3 2008 The ground-state structure of Ce@C82 is found to have the cerium atom attached to the six-membered ring on the C2 axis of the C82-C2v cage, and the encapsulated atom is found to perturb the carbon cage due to chemical bonding. Carbon 190-196 complement C8 beta chain Homo sapiens 33-36 16366555-3 2005 The cationic complex {[Ru]=C=CHCPh2CH2CMe=CH2}BF4 (3b) undergoes a cyclization process yielding 6b containing a eta2-cyclic allene ligand which is fully characterized by single-crystal X-ray diffraction analysis. Carbon 27-28 DNA polymerase iota Homo sapiens 112-116 18197643-3 2008 The ground-state structure of Ce@C82 is found to have the cerium atom attached to the six-membered ring on the C2 axis of the C82-C2v cage, and the encapsulated atom is found to perturb the carbon cage due to chemical bonding. Carbon 190-196 complement C8 beta chain Homo sapiens 126-129 27591667-3 2016 By using their synergistic effects of the remarkable mechanical, electrical, catalytic, and structural properties, ERGO@ZnPp-C60 incorporated in tetraoctylammonium bromide (TOAB) film was modified on the glassy carbon electrode (GCE) to construct a novel non-enzymatic electrochemical sensor. Carbon 211-217 glycine decarboxylase Homo sapiens 229-232 18267071-2 2008 Serine-3 of ghrelin is acylated with an eight-carbon fatty acid, octanoate, which is required for its endocrine actions. Carbon 46-52 appetite-regulating hormone Capra hircus 12-19 16299171-9 2005 Further, a microarray study using an anti-sense line showed AOX influences outside mitochondria, particularly in chloroplasts and on several carbon metabolism pathways. Carbon 141-147 alternative oxidase 2 Arabidopsis thaliana 60-63 16853611-6 2005 The specific capacity was found to be further improved when SnO(2) nanoparticles were supported on the carbon. Carbon 103-109 strawberry notch homolog 1 Homo sapiens 60-63 16853611-7 2005 The specific activity of Pt catalyst supported on the carbon materials for room-temperature methanol electrochemical oxidation was observed to be higher than that of a commercial Pt catalyst (E-TEK). Carbon 54-60 TEK receptor tyrosine kinase Homo sapiens 194-197 27723961-1 2016 We report an efficient method for fabricating flexible membranes of electrospun carbon nanofiber/tin(IV) sulfide (CNF@SnS2) core/sheath fibers. Carbon 80-86 sodium voltage-gated channel alpha subunit 11 Homo sapiens 118-122 18337701-5 2008 These results represent that cloned enzyme is verified as a carboxylesterase but not a lipase because esterase activity is decreased with rho-nitrophenyl ester contains more than 8 carbon chains but lipase activity does not affected with carbon chain length. Carbon 181-187 hydroxyphenylacetyl-CoA thioesterase PaaI Archaeoglobus fulgidus DSM 4304 68-76 16135531-5 2005 TAZ1 deletion in yeast leads to growth defects on nonfermentable carbon sources, indicative of a defect in respiration. Carbon 65-71 lysophosphatidylcholine acyltransferase Saccharomyces cerevisiae S288C 0-4 28335315-7 2016 On the other hand, apparent activation energy Eap for the methanol oxidation was also determined finding-as a rate determining step-the COads diffusion to the OHads for the catalysts supported on carbon nanofibers. Carbon 196-202 glutamyl aminopeptidase Homo sapiens 46-49 18202004-0 2008 Significance of zinc in a regulatory protein, CCM1, which regulates the carbon-concentrating mechanism in Chlamydomonas reinhardtii. Carbon 72-78 uncharacterized protein Chlamydomonas reinhardtii 46-50 16235944-2 2005 Esterification with a C(1-6) acid, and selective ozonolysis to release the C(23) carbonyl, complete the assembly of all the carbons present in the lituarine macrocyclic core. Carbon 124-131 nucleolin Homo sapiens 75-80 27462006-1 2016 We evaluated in vitro, the potential of the six pairs of ginsenoside isomers, stereoisomers at the chiral carbon on position 20, to inhibit the enzymatic activity of several UDP-glucuronosyltransferase (UGT) isoenzymes, major players in the human phase II drug metabolism. Carbon 106-112 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 174-201 16202243-8 2005 Fermentable carbon sources, such as glucose (at low concentrations), lactose and sucrose, as a sole carbon source, enhanced the synthesis of beta-galactosidase from the GGTII-lacZ fusion gene in wildtype KP1 cells but not in Pap1-negative cells. Carbon 100-106 galactosidase beta 1 Homo sapiens 141-159 16202243-9 2005 Glycerol, a non-fermentable carbon source, was also able to induce the synthesis of beta-galactosidase from the fusion gene, but other non-fermentable carbon sources such as acetate and ethanol were not. Carbon 28-34 galactosidase beta 1 Homo sapiens 84-102 16202243-9 2005 Glycerol, a non-fermentable carbon source, was also able to induce the synthesis of beta-galactosidase from the fusion gene, but other non-fermentable carbon sources such as acetate and ethanol were not. Carbon 151-157 galactosidase beta 1 Homo sapiens 84-102 18087617-4 2008 The oxidation signals of tyrosine residues of AS at carbon electrodes and the ability of fibrils to adsorb and catalyze hydrogen evolution at hanging mercury drop electrodes (HMDEs) decreased during incubation. Carbon 52-58 long intergenic non-protein coding RNA 2605 Homo sapiens 46-48 19275045-7 2008 The obtained results indicate that the examined factors (nitrogen and carbon availability) influence the CSH of Bacillus spp. Carbon 70-76 histocompatibility minor 13 Homo sapiens 121-124 16171347-2 2005 The thermal transformations of as-deposited Fe(CO)(5) films adsorbed on Au(111)/mica and C(4), C(8), C(12), and C(16) self-assembled methyl-terminated monolayer organic surfaces have been studied using infrared spectroscopy to probe how the physical restructuring influences the sensitivity of these systems to low-energy electron beams. Carbon 47-48 homeobox C8 Homo sapiens 95-99 27519409-9 2016 Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris. Carbon 177-183 aspartate transaminase AAT2 Saccharomyces cerevisiae S288C 67-71 27524233-1 2016 Elongation of very long chain fatty acids protein 6 (ELOVL6), a rate-limiting enzyme for the elongation of saturated and monounsaturated fatty acids with 12, 14, and 16 carbons, plays a key role in energy metabolism and insulin sensitivity. Carbon 169-176 ELOVL family member 6, elongation of long chain fatty acids (yeast) Mus musculus 0-51 16046082-1 2005 The Escherichia coli strain Pgi-UdhA, a mutant of the strain MG1655, is deficient in both the pgi gene and the udhA gene and cannot grow on glucose as carbon and energy source. Carbon 151-157 soluble pyridine nucleotide transhydrogenase Escherichia coli str. K-12 substr. MG1655 32-36 27524233-1 2016 Elongation of very long chain fatty acids protein 6 (ELOVL6), a rate-limiting enzyme for the elongation of saturated and monounsaturated fatty acids with 12, 14, and 16 carbons, plays a key role in energy metabolism and insulin sensitivity. Carbon 169-176 ELOVL family member 6, elongation of long chain fatty acids (yeast) Mus musculus 53-59 20641556-16 2004 NIR fluorescent dyes are conjugated RGD peptides such as Cy5.5-c(RGDyK), Cy5.5-c(RGDfK), and Cyp-RGD, which have been shown to visualize subcutaneously implanted integrin alphavbeta3-positive tumors (12-15). Carbon 11-12 peptidyl-prolyl isomerase G (cyclophilin G) Mus musculus 93-96 27242340-0 2016 PU-H71, a novel Hsp90 inhibitor, as a potential cancer-specific sensitizer to carbon-ion beam therapy. Carbon 78-84 heat shock protein, 3 Mus musculus 16-21 17881236-5 2007 Structure-activity relationships (SAR) indicate that increasing the steric bulk at the C(2)-purine position of NBMPR led to a decrease in binding affinity of these ligands at the hENT1. Carbon 87-88 solute carrier family 29 member 1 (Augustine blood group) Homo sapiens 179-184 16128814-4 2005 A carbon source-conditional strain with the NOP53 coding sequence under the control of the GAL1 promoter did not grow in glucose-containing medium, showing the phenotype of an essential gene. Carbon 2-8 galactokinase Saccharomyces cerevisiae S288C 91-95 16082667-6 2005 It is concluded that complete side-chain substitution of the bridgehead carbon atoms C-6 and C-12 in the indenofluorene unit, prior to indenofluorene ring formation, reduces the probability of keto formation. Carbon 72-78 complement C6 Homo sapiens 85-88 27573184-0 2016 Function of RSKS-1-AAK-2-DAF-16 signaling cascade in enhancing toxicity of multi-walled carbon nanotubes can be suppressed by mir-259 activation in Caenorhabditis elegans. Carbon 88-94 Ribosomal protein S6 kinase beta Caenorhabditis elegans 12-18 17932035-2 2007 Pma1 H(+)-ATPase, which is responsible for H(+)-dependent nutrient uptake in yeast (Saccharomyces cerevisiae), is one such example, displaying a rapid 5-10-fold increase in activity when carbon-starved cells are exposed to glucose. Carbon 187-193 H(+)-exporting P2-type ATPase PMA1 Saccharomyces cerevisiae S288C 0-4 17932035-5 2007 In carbon-starved cells with low Pma1 activity, peptide 896-918, which was derived from the C terminus upon Lys-C proteolysis, was found to be singly phosphorylated at Thr-912, whereas in glucose-metabolizing cells with high ATPase activity, the same peptide was doubly phosphorylated at Ser-911 and Thr-912. Carbon 3-9 H(+)-exporting P2-type ATPase PMA1 Saccharomyces cerevisiae S288C 33-37 27573184-0 2016 Function of RSKS-1-AAK-2-DAF-16 signaling cascade in enhancing toxicity of multi-walled carbon nanotubes can be suppressed by mir-259 activation in Caenorhabditis elegans. Carbon 88-94 5'-AMP-activated protein kinase catalytic subunit alpha-2 Caenorhabditis elegans 19-24 18047050-9 2007 Also carbon species produced were characterized by EA and TGA. Carbon 5-11 T-box transcription factor 1 Homo sapiens 58-61 27354064-2 2016 However, little is known about the SREBP-mediated control of processes that indirectly support lipogenesis, for instance, by supplying reducing power in the form of NAPDH or directing carbon flux into lipid precursors. Carbon 184-190 CCHC-type zinc finger nucleic acid binding protein Homo sapiens 35-40 27354064-7 2016 Treatment of cells with 25-hydroxycholesterol or statins, which respectively inhibit or activate SREBP, further supports SREBP-mediated regulation of IDH1 and, in cells with oncogenic IDH1, carbon flux into 2-HG. Carbon 190-196 CCHC-type zinc finger nucleic acid binding protein Homo sapiens 97-102 17574260-3 2007 According to the increment of silica, BET specific surface area was increased about thirty times and it was found that silica activated carbon materials were highly mesoporous by studying pore surface distribution and pore volume distribution. Carbon 136-142 delta/notch like EGF repeat containing Homo sapiens 38-41 27354064-7 2016 Treatment of cells with 25-hydroxycholesterol or statins, which respectively inhibit or activate SREBP, further supports SREBP-mediated regulation of IDH1 and, in cells with oncogenic IDH1, carbon flux into 2-HG. Carbon 190-196 CCHC-type zinc finger nucleic acid binding protein Homo sapiens 121-126 27419855-3 2016 SnO2- or SnS2-stabilized sulfur in porous carbon composites (SnO2/S/C and SnS2/S/C) have been obtained through a baked-in-salt or sealed-in-vessel approach at 245 C, starting from metallic tin (mp 231.89 C), excess sulfur, and porous carbon. Carbon 42-48 sodium voltage-gated channel alpha subunit 11 Homo sapiens 9-13 18330154-3 2007 Their reaction with carbon nanofibers was studied as a solid mixture by controlled heating in the DSC. Carbon 20-26 desmocollin 3 Homo sapiens 98-101 18330156-1 2007 Polymer grafting of polystyrene (PS) on nitrogen-doped multiwall carbon nanotubes (CNx) was successfully obtained by a "grafting from" technique. Carbon 65-71 calnexin Homo sapiens 83-86 18330156-3 2007 The polymer-grafting carbon nanotubes synthesis includes the free radical functionalization of CNx and the "controlled/living" Nitroxide Mediated Radical Polymerization (NMRP). Carbon 21-27 calnexin Homo sapiens 95-98 27419855-3 2016 SnO2- or SnS2-stabilized sulfur in porous carbon composites (SnO2/S/C and SnS2/S/C) have been obtained through a baked-in-salt or sealed-in-vessel approach at 245 C, starting from metallic tin (mp 231.89 C), excess sulfur, and porous carbon. Carbon 236-242 sodium voltage-gated channel alpha subunit 11 Homo sapiens 9-13 27394173-10 2016 Ogdh is also an important ROS generator regardless of whether pyruvate or succinate serve as the sole source of carbon. Carbon 112-118 oxoglutarate dehydrogenase Homo sapiens 0-4 17640694-9 2007 Together with earlier work showing Iso-C affinity at GluR6 receptors to be 240-fold lower than DA, our results suggest that neuroexcitatory effects of Iso-A in CA1 may involve both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) and KA receptors, while Iso-C likely involves the activation of AMPA receptors alone. Carbon 39-40 glutamate ionotropic receptor kainate type subunit 2 Rattus norvegicus 53-58 32263150-5 2016 Our results showed that the polymer dots and carbon nanodots inhibit hIAPP fibrillation, while the GQDs promoted the formation of hIAPP fibrils. Carbon 45-51 islet amyloid polypeptide Homo sapiens 69-74 17404806-4 2007 Furthermore, the T(1rho) of the beta-GA carbonyl carbon was measured by (13)C solid-state NMR, and T(g) was measured by modulated temperature differential scanning calorimetry. Carbon 40-46 galactosidase beta 1 Homo sapiens 32-39 17404806-8 2007 The local mobility of beta-GA, as determined by the T(1rho) of the beta-GA carbonyl carbon, was more markedly decreased by the addition of sucrose than by the addition of stachyose. Carbon 75-81 galactosidase beta 1 Homo sapiens 22-29 17404806-8 2007 The local mobility of beta-GA, as determined by the T(1rho) of the beta-GA carbonyl carbon, was more markedly decreased by the addition of sucrose than by the addition of stachyose. Carbon 75-81 galactosidase beta 1 Homo sapiens 67-74 27332739-7 2016 The as-made hierarchically porous carbons MOPs-C show an obvious increase in the BET surface area (from 819 to 1824 m(2) g(-1)). Carbon 34-41 delta/notch like EGF repeat containing Homo sapiens 81-84 27402745-2 2016 The experimentally determined ligand specificities of several solute binding proteins (SBPs) for TRAP (tripartite ATP-independent permease) transporters for four-carbon acids, including d-erythronate and l-erythronate, were used to constrain the substrates for the catabolic pathways that degrade the SBP ligands to intermediates in central carbon metabolism. Carbon 162-168 selenium binding protein 1 Homo sapiens 87-90 17516063-7 2007 N. crassa ADH1 preferred primary alcohols containing C3-C8 carbons to secondary alcohols such as 2-propanol and 2-butanol. Carbon 59-66 alcohol dehydrogenase I Neurospora crassa OR74A 10-14 26872481-5 2016 The purpose of these simulations is to study the interaction between a single-wall carbon nanotube (SWCNT) and hTRPV1, and the diffusion of doxorubicin (DOX) across hTRPV1 and across a POPC lipid membrane. Carbon 83-89 transient receptor potential cation channel subfamily V member 1 Homo sapiens 111-117 17677502-6 2007 We observe that c(0,t), c(1,t), and c(2,t) decay to 0 (no correlation) more slowly and the maximum values of c(1,t) and c(2,t) are lower for low values of k1/k0 as compared to high values of k1/k0. Carbon 16-17 keratin 1 Homo sapiens 155-160 17677502-6 2007 We observe that c(0,t), c(1,t), and c(2,t) decay to 0 (no correlation) more slowly and the maximum values of c(1,t) and c(2,t) are lower for low values of k1/k0 as compared to high values of k1/k0. Carbon 16-17 keratin 1 Homo sapiens 191-196 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 growth arrest and DNA damage inducible alpha Homo sapiens 193-200 17345630-3 2007 This suggests a significant increase in the size of the enzyme hydrophobic tunnel from approximately 1000 A(3) of E. coli UPPs to approximately 1300 A(3) required to accommodate C(80) in Rer2p and to 1700 A(3) for C(110) in Srt1p. Carbon 178-179 ditrans,polycis-polyprenyl diphosphate synthase Saccharomyces cerevisiae S288C 187-192 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 solute carrier family 19 member 1 Homo sapiens 286-293 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Homo sapiens 295-299 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Homo sapiens 305-309 17397903-7 2007 The thermal decomposition of AO7 adsorbed on the activated carbon and the composite was investigated by in situ FTIR, respectively. Carbon 59-65 ring finger protein 25 Homo sapiens 29-32 27110680-0 2016 A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Carbon 67-73 phosphoglycerate dehydrogenase Homo sapiens 2-7 17562468-4 2007 LA and LG activities alone and their ratio with organic-C (ratio index value, RIV), straw and grain yield were higher in DCM than MSWC-treated soils, due to higher amount of biogenic organic materials like water-soluble organic carbon, carbohydrate and mineralizable nitrogen in the former. Carbon 228-234 asparaginase and isoaspartyl peptidase 1 Bos taurus 0-2 27110680-6 2016 Surprisingly, PHGDH inhibition reduced the incorporation into nucleotides of one-carbon units from glucose-derived and exogenous serine. Carbon 81-87 phosphoglycerate dehydrogenase Homo sapiens 14-19 27110680-7 2016 We conclude that glycolytic serine synthesis coordinates the use of one-carbon units from endogenous and exogenous serine in nucleotide synthesis, and we suggest that one-carbon unit wasting thus may contribute to the efficacy of PHGDH inhibitors in vitro and in vivo. Carbon 171-177 phosphoglycerate dehydrogenase Homo sapiens 230-235 17562315-4 2007 The crystal structure of ADPS from Dictyostelium discoideum shows a fatty-alcohol molecule bound in a narrow hydrophobic tunnel, specific for aliphatic chains of 16 carbons. Carbon 165-172 alkylglycerone phosphate synthase Homo sapiens 25-29 27251132-0 2016 Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-beta-mediated Akt/GSK-3beta/SNAIL-1 signalling pathway. Carbon 13-19 glycogen synthase kinase 3 beta Homo sapiens 146-155 27082127-0 2016 Specific Surface versus Electrochemically Active Area of the Carbon/Polypyrrole Capacitor: Correlation of Ion Dynamics Studied by an Electrochemical Quartz Crystal Microbalance with BET Surface. Carbon 61-67 delta/notch like EGF repeat containing Homo sapiens 182-185 17425347-3 2007 Our XPS results showed that the surface reaction between OTS-SAMs and oxygen plasma can generate new surface functional groups such as alcohol (C-O), aldehyde (C=O), and carboxylic acid (O-C=O), and their compositions can be controlled by using different treatment times and powers. Carbon 144-145 methionine adenosyltransferase 1A Homo sapiens 61-65 17425347-3 2007 Our XPS results showed that the surface reaction between OTS-SAMs and oxygen plasma can generate new surface functional groups such as alcohol (C-O), aldehyde (C=O), and carboxylic acid (O-C=O), and their compositions can be controlled by using different treatment times and powers. Carbon 160-161 methionine adenosyltransferase 1A Homo sapiens 61-65 27055178-1 2016 The 1,1-ADEQUATE spectrum clearly shows specific two-bond proton to carbon correlations to unequivocally distinguish the major and minor regioisomers of ortho-halogenated pyridines and to aid in assignment of the corresponding proton and carbon chemical shifts. Carbon 68-74 activation induced cytidine deaminase Homo sapiens 188-191 17355124-1 2007 Glutamine synthetase adenylyltransferase (ATase) regulates the activity of glutamine synthetase by adenylylation and deadenylylation in response to signals of nitrogen and carbon status: glutamine, alpha-ketoglutarate, and the uridylylated and unmodified forms of the PII signal transduction protein. Carbon 172-178 adenylyltransferase Escherichia coli 21-40 26938777-0 2016 MOF-Derived Hollow Co9 S8 Nanoparticles Embedded in Graphitic Carbon Nanocages with Superior Li-Ion Storage. Carbon 62-68 lysine acetyltransferase 8 Homo sapiens 0-3 17160390-1 2007 A new and label-free capacitive immunosensor based on antibody-functionalized epoxysilane on a glassy carbon electrode has been developed for quantitative detection of human chorionic gonadotropin (hCG). Carbon 102-108 chorionic gonadotropin subunit beta 5 Homo sapiens 174-202 17331505-5 2007 All the carbon materials tested showed substantial anti-angiogenic activity against either FGF2- or VEGF-induced angiogenesis in the CAM model. Carbon 8-14 fibroblast growth factor 2 Gallus gallus 91-95 26938777-1 2016 Novel electrode materials consisting of hollow cobalt sulfide nanoparticles embedded in graphitic carbon nanocages (HCSP GCC) are facilely synthesized by a top-down route applying room-temperature synthesized Co-based zeolitic imidazolate framework (ZIF-67) as the template. Carbon 98-104 guanylate cyclase 2C Homo sapiens 121-124 17331505-5 2007 All the carbon materials tested showed substantial anti-angiogenic activity against either FGF2- or VEGF-induced angiogenesis in the CAM model. Carbon 8-14 vascular endothelial growth factor A Gallus gallus 100-104 26938777-2 2016 Owing to the good mechanical flexibility and pronounced structure stability of carbon nanocages-encapsulated Co9 S8 , the as-obtained HCSP GCC exhibit superior Li-ion storage. Carbon 79-85 guanylate cyclase 2C Homo sapiens 139-142 27112822-10 2016 For one hundred genes, we predict that direct control of mRNA stability by CsrA might contribute to metabolic adaptation by regulating expression of genes involved in carbon metabolism and transport independently of transcriptional regulation. Carbon 167-173 carbon storage regulator Escherichia coli str. K-12 substr. MG1655 75-79 17139481-4 2007 A hydrogen bond detected in HPr(Ser46P) between one phosphate-group oxygen and a side-chain hydrogen of Asn43-an amino acid conserved in all HPr proteins of Gram-positive bacteria that regulate their carbon consumption by CCR-might fulfil an important role in CcpA-HPr(Ser46P) complex formation. Carbon 200-206 haptoglobin-related protein Homo sapiens 28-31 17139481-4 2007 A hydrogen bond detected in HPr(Ser46P) between one phosphate-group oxygen and a side-chain hydrogen of Asn43-an amino acid conserved in all HPr proteins of Gram-positive bacteria that regulate their carbon consumption by CCR-might fulfil an important role in CcpA-HPr(Ser46P) complex formation. Carbon 200-206 haptoglobin-related protein Homo sapiens 141-144 17139481-4 2007 A hydrogen bond detected in HPr(Ser46P) between one phosphate-group oxygen and a side-chain hydrogen of Asn43-an amino acid conserved in all HPr proteins of Gram-positive bacteria that regulate their carbon consumption by CCR-might fulfil an important role in CcpA-HPr(Ser46P) complex formation. Carbon 200-206 haptoglobin-related protein Homo sapiens 141-144 15792584-4 2005 The BET surface area and pore volume of activated carbon prepared from vacuum pyrolysis char were 1150 m2/g and 0.43 cm3/g, respectively. Carbon 50-56 delta/notch like EGF repeat containing Homo sapiens 4-7 27548948-1 2016 To improve the adsorption selectivity of volatile organic compounds ( VOCs) , activated carbon ( AC) was modified by polydimethylsiloxane (PDMS) and characterized by BET analysis and Boehm titration. Carbon 88-94 delta/notch like EGF repeat containing Homo sapiens 166-169 16028941-4 2005 In the case of chelating diethers, measurement of the corresponding equilibrium constants establish more stable eta(6),eta(5) adducts with five- over four-membered chelates and with smaller oxygen and carbon backbone substituents. Carbon 201-207 endothelin receptor type A Homo sapiens 112-115 16028941-4 2005 In the case of chelating diethers, measurement of the corresponding equilibrium constants establish more stable eta(6),eta(5) adducts with five- over four-membered chelates and with smaller oxygen and carbon backbone substituents. Carbon 201-207 endothelin receptor type A Homo sapiens 119-122 15948949-0 2005 Transcriptional regulation of the one-carbon metabolism regulon in Saccharomyces cerevisiae by Bas1p. Carbon 38-44 Bas1p Saccharomyces cerevisiae S288C 95-100 17190830-4 2007 Binding of PUX1 to AtCDC48 was mediated through a region containing both the UBX domain and the immediate C-terminal flanking amino acids (UBX-C). Carbon 21-22 plant UBX domain-containing protein 1 Arabidopsis thaliana 11-15 26634234-5 2016 The X-ray structures of E-1a, E-1b and E-1c show a slightly shortened N-C bond to the alkene moieties. Carbon 72-73 branched chain keto acid dehydrogenase E1 subunit beta Homo sapiens 30-34 17183213-6 2007 We show here that while Glk is made constitutively throughout the growth of Streptomyces coelicolor A3(2), its catalytic activity is modulated in a carbon source-dependent manner: while cultures growing exponentially on glucose exhibit high Glk activity, mannitol- grown cultures show negligible activity. Carbon 148-154 mitogen-activated protein kinase kinase kinase kinase 3 Homo sapiens 24-27 17183215-0 2007 Transcriptome analysis of temporal regulation of carbon metabolism by CcpA in Bacillus subtilis reveals additional target genes. Carbon 49-55 transcriptional regulator of catabolite repression (Lacl family) Bacillus subtilis subsp. subtilis str. 168 70-74 17183215-1 2007 The pleiotropic regulator of carbon metabolism in Gram-positive bacteria, CcpA, regulates gene expression by binding to so-called cre elements, which are located either upstream or in promoter regions, or in open-reading frames. Carbon 29-35 transcriptional regulator of catabolite repression (Lacl family) Bacillus subtilis subsp. subtilis str. 168 74-78 15878986-4 2005 Comparison of circadian changes in transcript abundance of lignin biosynthetic genes between wild-type plants and the sex1 mutant, which is impaired in starch turnover, suggested that carbon availability related to starch turnover might determine the capacity to synthesize lignins. Carbon 184-190 Pyruvate phosphate dikinase, PEP/pyruvate binding domain-containing protein Arabidopsis thaliana 118-122 27071007-3 2016 Among them, the Lsr (LuxS-regulated) QS system is conserved in scores of bacteria, and its signal molecule, autoinducer-2 (AI-2), is synthesized as a product of 1-carbon metabolism. Carbon 163-169 Lutheran suppressor, X-linked Homo sapiens 21-25 16037982-1 2005 Multiwall CNx nanotubes, nanoonions, and amorphous nanoballs were formed by carbon DC arc evaporation in a nitrogen atmosphere. Carbon 76-82 calnexin Homo sapiens 10-13 17115712-7 2006 In contrast, the FXa-catalyzed hydrolysis of N-alpha-Z-D-Arg-Gly-Arg-pNA.2HCl (S-2765) and H-D-Ile-L-Pro-L-Arg-pNA.HCl (S-2288) is most consistent with two-proton bridges forming at the transition state between Ser195 OgammaH and His57 N(epsilon)2 and His57 Ndelta1 and Asp102 COObeta- at the active site, with transition-state fractionation factors of phi1 = phi2 = 0.57 +/- 0.07 and phiS = 0.78 +/- 0.16 for solvent rearrangement for S-2765 and phi1 = phi2 = 0.674 +/- 0.001 for S-2288 under enzyme saturation with the substrate at pH 8.40 and 25.0 +/- 0.1 degrees C. The rate-determining step(s) in these reactions is most likely the cleavage of the C-N bond and departure of the leaving group. Carbon 75-76 protein phosphatase 1 regulatory inhibitor subunit 14B Homo sapiens 353-357 17115712-7 2006 In contrast, the FXa-catalyzed hydrolysis of N-alpha-Z-D-Arg-Gly-Arg-pNA.2HCl (S-2765) and H-D-Ile-L-Pro-L-Arg-pNA.HCl (S-2288) is most consistent with two-proton bridges forming at the transition state between Ser195 OgammaH and His57 N(epsilon)2 and His57 Ndelta1 and Asp102 COObeta- at the active site, with transition-state fractionation factors of phi1 = phi2 = 0.57 +/- 0.07 and phiS = 0.78 +/- 0.16 for solvent rearrangement for S-2765 and phi1 = phi2 = 0.674 +/- 0.001 for S-2288 under enzyme saturation with the substrate at pH 8.40 and 25.0 +/- 0.1 degrees C. The rate-determining step(s) in these reactions is most likely the cleavage of the C-N bond and departure of the leaving group. Carbon 75-76 protein phosphatase 1 regulatory inhibitor subunit 14B Homo sapiens 447-451 16899252-2 2006 The modified carbon samples obtained by acid and ammonia treatment of the conventional sample had a higher BET surface area (989 and 1010 m2 g-1, respectively) and higher specific mesopore surface area (27.36 and 33.21 m2 g-1, respectively) compared to the untreated material (820 and 18.25 m2 g-1). Carbon 13-19 delta/notch like EGF repeat containing Homo sapiens 107-110 15797334-3 2005 The dry and wet stability of Drosophila acetylcholinesterase non-covalently immobilized onto polyethyleneimine modified screen-printed carbon electrodes was improved when compared to non-immobilized acetylcholinesterase, and acetylcholinesterase covalently immobilized onto dialdehyde and polyethyleneimine modified electrodes. Carbon 135-141 Acetylcholine esterase Drosophila melanogaster 40-60 26775155-4 2016 The BET surface area, total pore volume and mesopore volume of the activated carbons from tyre char have been improved to 732 m(2)/g, 0.91 cm(3)/g and 0.89 cm(3)/g, respectively. Carbon 77-84 delta/notch like EGF repeat containing Homo sapiens 4-7 15677766-6 2005 After ingestion of either MCFAs or MCTs, the carbon chain lengths of the acyl groups attached to nascent ghrelin molecules corresponded to that of the ingested MCFAs or MCTs. Carbon 45-51 ghrelin Mus musculus 105-112 26848826-0 2016 Investigation of the Interactions and Bonding between Carbon and Group VIII Metals at the Atomic Scale. Carbon 54-60 cytochrome c oxidase subunit 8A Homo sapiens 71-75 15851104-0 2005 Bat2p is essential in Saccharomyces cerevisiae for fusel alcohol production on the non-fermentable carbon source ethanol. Carbon 99-105 branched-chain-amino-acid transaminase BAT2 Saccharomyces cerevisiae S288C 0-5 15851104-10 2005 In the circumstances used, gene expression analysis revealed a strong upregulation of BAT2 gene activity in the wild type, when cells grew on ethanol as carbon source. Carbon 153-159 branched-chain-amino-acid transaminase BAT2 Saccharomyces cerevisiae S288C 86-90 15851104-15 2005 Therefore we conclude that the expression of BAT2 is essential for 3-methyl-1-butanol formation on the non-fermentable carbon source, ethanol. Carbon 119-125 branched-chain-amino-acid transaminase BAT2 Saccharomyces cerevisiae S288C 45-49 15851105-3 2005 In the context of the control of carbon metabolism, previous data had demonstrated that Pkc1p might play a central role in the control of cellular growth and metabolism in yeast. Carbon 33-39 protein kinase C Saccharomyces cerevisiae S288C 88-93 15668256-5 2005 The enzyme can elongate acyl-chains containing 2-14 carbon atoms with malonyl moieties attached in thioester linkage to the human mitochondrial acyl carrier protein and is able to restore growth to the respiratory-deficient yeast mutant cem1 that lacks the endogenous mitochondrial beta-ketoacyl synthase and exhibits lowered lipoic acid levels. Carbon 52-58 NADH:ubiquinone oxidoreductase subunit AB1 Homo sapiens 130-164 16376615-0 2006 The carbon starvation-inducible genes Rv2557 and Rv2558 of Mycobacterium tuberculosis are not required for long-term survival under carbon starvation and for virulence in SCID mice. Carbon 4-10 hypothetical protein Mycobacterium tuberculosis H37Rv 38-44 16376615-0 2006 The carbon starvation-inducible genes Rv2557 and Rv2558 of Mycobacterium tuberculosis are not required for long-term survival under carbon starvation and for virulence in SCID mice. Carbon 4-10 hypothetical protein Mycobacterium tuberculosis H37Rv 49-55 16782343-3 2006 13C-31P RDX (Rotational-Echo Double Resonance for X-clusters) experiments clearly revealed the REDOR dephasing effects for carbon atoms residing in the both terminal parts, whereas no dephasing was observed for the middle parts including polyolefinic C20-C33 and hydroxyl-bearing C8/C9 parts. Carbon 123-129 homeobox C8 Homo sapiens 280-285 26938218-9 2016 Glycine and CPS1 are connected through the one-carbon pool by the folate pathway and the urea cycle. Carbon 47-53 carbamoyl-phosphate synthase 1 Homo sapiens 12-16 32689301-0 2006 Viewpoint: How large is the carbon isotope fractionation of the photorespiratory enzyme glycine decarboxylase? Carbon 28-34 glycine decarboxylase Homo sapiens 88-109 15766878-3 2005 The chimeric carrier, Anc2-Cyc1(His6)p, was able to restore growth on a non-fermentable carbon source of a yeast strain devoid of functional ADP/ATP carrier, which demonstrated its transport activity. Carbon 88-94 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 22-26 26792489-10 2016 Taken together, these data strongly suggest that carbon skeletons deriving from BAM1 diurnal degradation of transitory starch support the biosynthesis of proline required to face the osmotic stress. Carbon 49-55 beta-amylase 1 Arabidopsis thaliana 80-84 15745801-1 2005 Attachment of a glucose moiety to 6-beta-aminomorphine afforded compound 3, where the glucose moiety was linked to the C-6 nitrogen atom by a two-carbon bridge. Carbon 146-152 complement C6 Homo sapiens 119-122 16982895-7 2006 The additional two mannoses in PIM4, relative to PIM2, are located at the distal 6" carbon of the alpha1-alpha6-linked mannose and would project away from the CD1d binding groove for interaction with the TCR. Carbon 84-90 proviral integration site 2 Mus musculus 49-53 27476200-4 2016 Rhizobial evolution caused by development and diversification of the Nod factor synthesizing systems may result in both increased host specificity range (transition of Bradyrhizobium from autotrophic to symbiotrophic carbon metabolism in interaction with a broad spectrum of legumes) and to its contraction (transition of Rhizobium and Sinorhizobium to "altruistic" interaction with legumes of the galegoid clade). Carbon 217-223 atrophin 1 Homo sapiens 69-72 17050187-3 2006 A leave-one-out (LOO) cross validation procedure resulted in the selection of three descriptors, the total of electron and nuclear energies of the two-center terms for the carbon-chlorine or carbon-nitrogen bond (TE2), the net atomic charges on the chlorine or nitrogen (qx), and the largest negative atomic charge on an atom (q-). Carbon 172-178 N-alpha-acetyltransferase 10, NatA catalytic subunit Homo sapiens 213-216 16883433-1 2006 A new bisphosphine ligand, C8-BINAP, and C8-BINAP-stabilized palladium nanoparticles have been prepared; C8-BINAP was found to be an effective protecting ligand for preparing and stabilizing palladium nanoparticles with very small core size and narrow size distribution and the C8-BINAP-Pd nanoparticles behave as an efficient catalyst for carbon-carbon coupling reactions at room temperature. Carbon 340-346 homeobox C8 Homo sapiens 27-35 16883433-1 2006 A new bisphosphine ligand, C8-BINAP, and C8-BINAP-stabilized palladium nanoparticles have been prepared; C8-BINAP was found to be an effective protecting ligand for preparing and stabilizing palladium nanoparticles with very small core size and narrow size distribution and the C8-BINAP-Pd nanoparticles behave as an efficient catalyst for carbon-carbon coupling reactions at room temperature. Carbon 340-346 homeobox C8 Homo sapiens 41-49 16851224-4 2005 Steady-state isotopic transient kinetic analysis was used to evaluate the intrinsic turnover frequency (TOF intr) and the surface coverage of carbon-containing species (theta COx) on the gold catalyst during CO oxidation at 1.2 atm total pressure and 296 K. The artifacts in the kinetic parameters caused by re-adsorption of product carbon dioxide were removed by varying the total flow rate. Carbon 142-148 cytochrome c oxidase subunit 8A Homo sapiens 175-178 15773496-0 2005 Comment on "addition of carbon sorbents to reduce PCB and PAH bioavailability in marine sediments: physicochemical tests". Carbon 24-30 phenylalanine hydroxylase Homo sapiens 58-61 15483318-4 2005 We hypothesized that beta-glucuronidase (gus) genes may be prone to LGT from bacteria to fungi (thought to lack gus) because this would enable fungi to utilize glucuronides in vertebrate urine as a carbon source. Carbon 198-204 glucuronidase beta Homo sapiens 21-39 15483318-4 2005 We hypothesized that beta-glucuronidase (gus) genes may be prone to LGT from bacteria to fungi (thought to lack gus) because this would enable fungi to utilize glucuronides in vertebrate urine as a carbon source. Carbon 198-204 glucuronidase beta Homo sapiens 41-44 16883433-1 2006 A new bisphosphine ligand, C8-BINAP, and C8-BINAP-stabilized palladium nanoparticles have been prepared; C8-BINAP was found to be an effective protecting ligand for preparing and stabilizing palladium nanoparticles with very small core size and narrow size distribution and the C8-BINAP-Pd nanoparticles behave as an efficient catalyst for carbon-carbon coupling reactions at room temperature. Carbon 340-346 homeobox C8 Homo sapiens 41-49 16883433-1 2006 A new bisphosphine ligand, C8-BINAP, and C8-BINAP-stabilized palladium nanoparticles have been prepared; C8-BINAP was found to be an effective protecting ligand for preparing and stabilizing palladium nanoparticles with very small core size and narrow size distribution and the C8-BINAP-Pd nanoparticles behave as an efficient catalyst for carbon-carbon coupling reactions at room temperature. Carbon 340-346 homeobox C8 Homo sapiens 41-49 26841976-9 2016 Compared to the case on H-FAU, the metal cations on M-FAU increase the difficulty of occurrence of bimolecular polymerization and subsequent C-S bond cracking steps. Carbon 0-1 FAU ubiquitin like and ribosomal protein S30 fusion Homo sapiens 26-29 16883433-1 2006 A new bisphosphine ligand, C8-BINAP, and C8-BINAP-stabilized palladium nanoparticles have been prepared; C8-BINAP was found to be an effective protecting ligand for preparing and stabilizing palladium nanoparticles with very small core size and narrow size distribution and the C8-BINAP-Pd nanoparticles behave as an efficient catalyst for carbon-carbon coupling reactions at room temperature. Carbon 347-353 homeobox C8 Homo sapiens 27-35 16883433-1 2006 A new bisphosphine ligand, C8-BINAP, and C8-BINAP-stabilized palladium nanoparticles have been prepared; C8-BINAP was found to be an effective protecting ligand for preparing and stabilizing palladium nanoparticles with very small core size and narrow size distribution and the C8-BINAP-Pd nanoparticles behave as an efficient catalyst for carbon-carbon coupling reactions at room temperature. Carbon 347-353 homeobox C8 Homo sapiens 41-49 16883433-1 2006 A new bisphosphine ligand, C8-BINAP, and C8-BINAP-stabilized palladium nanoparticles have been prepared; C8-BINAP was found to be an effective protecting ligand for preparing and stabilizing palladium nanoparticles with very small core size and narrow size distribution and the C8-BINAP-Pd nanoparticles behave as an efficient catalyst for carbon-carbon coupling reactions at room temperature. Carbon 347-353 homeobox C8 Homo sapiens 41-49 16883433-1 2006 A new bisphosphine ligand, C8-BINAP, and C8-BINAP-stabilized palladium nanoparticles have been prepared; C8-BINAP was found to be an effective protecting ligand for preparing and stabilizing palladium nanoparticles with very small core size and narrow size distribution and the C8-BINAP-Pd nanoparticles behave as an efficient catalyst for carbon-carbon coupling reactions at room temperature. Carbon 347-353 homeobox C8 Homo sapiens 41-49 15590280-3 2005 Moreover, the possibility of direct electron transfer from the reduced form of FCb2 to carbon electrodes has been evaluated. Carbon 87-93 L-lactate dehydrogenase (cytochrome) Saccharomyces cerevisiae S288C 79-83 15665286-5 2005 Both proton and carbon ion irradiation decreased cell migration and invasion in a dose-dependent manner and strongly inhibited matrix metalloproteinase-2 activity. Carbon 16-22 matrix metallopeptidase 2 Homo sapiens 127-153 26841976-9 2016 Compared to the case on H-FAU, the metal cations on M-FAU increase the difficulty of occurrence of bimolecular polymerization and subsequent C-S bond cracking steps. Carbon 0-1 FAU ubiquitin like and ribosomal protein S30 fusion Homo sapiens 54-57 26813621-7 2016 In the absence of a functioning malate shuttle, dct2 lines survive through the enhanced use of the phosphoenolpyruvate carboxykinase carbon shuttle pathway that in wild-type maize accounts for ~ 25% of the photosynthetic activity. Carbon 133-139 phosphoenolpyruvate carboxykinase (ATP) Zea mays 99-132 15647465-7 2005 The class II OR1G1 was revealed to be broadly tuned towards odorants of 9-10 carbon chain length, with diverse functional groups. Carbon 77-83 olfactory receptor family 1 subfamily G member 1 Homo sapiens 13-18 15632429-1 2005 It was previously shown that MRG19 downregulates carbon metabolism in Saccharomyces cerevisiae upon glucose exhaustion, and that the gene is glucose repressed. Carbon 49-55 Csr2p Saccharomyces cerevisiae S288C 29-34 15632429-2 2005 Here, it is shown that glucose repression of MRG19 is overcome upon nitrogen withdrawal, suggesting that MRG19 is a regulator of carbon and nitrogen metabolism. Carbon 129-135 Csr2p Saccharomyces cerevisiae S288C 45-50 17111600-1 2006 A method of compound-specific stable carbon isotopic analysis for the research about the sources of atmospheric formaldehyde was preliminary studied using gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS) via 2, 4-dinitrophenylhydrazine (DNPH) derivatization. Carbon 37-43 guanylate cyclase 2C Homo sapiens 218-222 16617161-2 2006 Although human CYP24A1 catalyzes both C-23 and C-24 oxidation pathways, rat CYP24A1 shows almost no C-23 oxidation pathway. Carbon 15-16 nucleolin Homo sapiens 38-42 15632429-2 2005 Here, it is shown that glucose repression of MRG19 is overcome upon nitrogen withdrawal, suggesting that MRG19 is a regulator of carbon and nitrogen metabolism. Carbon 129-135 Csr2p Saccharomyces cerevisiae S288C 105-110 26653077-1 2016 Recently we presented structure-reactivity correlations for the gas-phase ambient-temperature rate constants for hydrogen abstraction from sp(3)-hybridized carbon by chlorine atom and hydroxyl radical (Cl /HO + HCR3 HCl/HOH + CR3); the reaction enthalpy effect was represented by the independent variable DeltarH and the "polar effect" by the independent variables F and R, the Hammett constants for field/inductive and resonance effects. Carbon 156-162 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 213-216 15632429-5 2005 MRG19 disruptants showed reduced pseudohyphal formation and enhanced sporulation, a phenomenon that occurs under conditions of both nitrogen and carbon withdrawal. Carbon 145-151 Csr2p Saccharomyces cerevisiae S288C 0-5 15632429-6 2005 These studies revealed that MRG19 regulates carbon and nitrogen metabolism, as well as morphogenetic changes, suggesting that MRG19 is a component of the link between the metabolic status of the cell and the corresponding developmental pathway. Carbon 44-50 Csr2p Saccharomyces cerevisiae S288C 28-33 15632429-6 2005 These studies revealed that MRG19 regulates carbon and nitrogen metabolism, as well as morphogenetic changes, suggesting that MRG19 is a component of the link between the metabolic status of the cell and the corresponding developmental pathway. Carbon 44-50 Csr2p Saccharomyces cerevisiae S288C 126-131 16609797-1 2006 Reaction of LAl[eta2-(CSiMe3)2] (L = HC[(CMe)(NAr)]2, Ar = 2,6-iPr2C6H3) with carbon monoxide and tert-butyl isocyanide afforded unique AlC3 aluminacyclobutenes via insertion into one of the aluminium-carbon bonds. Carbon 78-84 lipase A, lysosomal acid type Homo sapiens 12-15 26399226-6 2016 Organometallic complexes with the TiE2 (E = OH and SH) decoration on the edge of aromatic hydrocarbons have been computationally designed, which feature 1,3-metal-carbon (1,3-MC) bonding between titanium and planar tetracoordinate beta-carbon. Carbon 95-101 TEK receptor tyrosine kinase Homo sapiens 34-38 16606846-0 2006 Evidence for C-H cleavage by an iron-superoxide complex in the glycol cleavage reaction catalyzed by myo-inositol oxygenase. Carbon 13-14 myo-inositol oxygenase Homo sapiens 105-123 16529466-0 2006 Acetylenic carbon-13 chemical shift tensors for diphenylacetylene and (eta2-Diphenylacetylene)Pt(PPh3)2: a solid-state NMR and theoretical study. Carbon 11-17 DNA polymerase iota Homo sapiens 71-75 15556357-2 2004 Modification of carbon surface for immobilization of acetylcholinesterase. Carbon 16-22 Acetylcholine esterase Drosophila melanogaster 53-73 15556357-3 2004 Screen-printed carbon electrodes modified with the dialdehydes, glutaraldehyde and terephthaldicarboxaldehyde, and then polyethyleneimine have been utilized for production of pesticide biosensors based on acetylcholinesterase. Carbon 15-21 Acetylcholine esterase Drosophila melanogaster 205-225 26628211-4 2016 A significant rise in the BET surface area is observed for SnO2 pillared carbon, when compared to pristine GO. Carbon 73-79 delta/notch like EGF repeat containing Homo sapiens 26-29 15498869-2 2004 Uniquely among condensing enzymes, 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase (HMGS) catalyzes the formation of a carbon-carbon bond by activating the methyl group of an acetylated cysteine. Carbon 117-123 3-hydroxy-3-methylglutaryl-CoA synthase 2 Homo sapiens 35-80 15498869-2 2004 Uniquely among condensing enzymes, 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase (HMGS) catalyzes the formation of a carbon-carbon bond by activating the methyl group of an acetylated cysteine. Carbon 124-130 3-hydroxy-3-methylglutaryl-CoA synthase 2 Homo sapiens 35-80 15515070-1 2004 Nanocast silica (NCS-1) was synthesized by a casting process by employing the mesoporous carbon CMK-3 (the replica of SBA-15) as a template, tetraethoxysilane (TEOS) as the silica source, and hydrochloric acid (HCl) as the catalyst. Carbon 89-95 neuronal calcium sensor 1 Homo sapiens 17-22 15515070-6 2004 The structure of NCS-1 is strongly influenced by variables of the nanocasting process, such as the loading amount of silica, hydrolysis temperature, and carbon removal methods. Carbon 153-159 neuronal calcium sensor 1 Homo sapiens 17-22 16503343-2 2006 The TiO2/AC was characterized by BET, SEM, XRD and optical absorption spectroscopy. Carbon 9-11 delta/notch like EGF repeat containing Homo sapiens 33-36 26257095-7 2015 Nitrogen adsorption-desorption results showed that the carbon materials had large BET surface area and pore volume, e.g., 1426 m(2)/g and 1.67 cm(3)/g for the sample carbonized at 800 C. Moreover, the pore structure and surface chemistry compositions were tunable, as they were sensitive to the temperature. Carbon 55-61 delta/notch like EGF repeat containing Homo sapiens 82-85 26619894-0 2015 Three-Dimensional Nanoporous Graphene-Carbon Nanotube Hybrid Frameworks for Confinement of SnS2 Nanosheets: Flexible and Binder-Free Papers with Highly Reversible Lithium Storage. Carbon 38-44 sodium voltage-gated channel alpha subunit 11 Homo sapiens 91-95 16365037-6 2006 The regulation and metabolic role of MTHFS in one-carbon metabolism was investigated in vitro and in human neuroblastoma cells. Carbon 50-56 methenyltetrahydrofolate synthetase Homo sapiens 37-42 16365037-12 2006 The sequestration of 10-formylTHF by MTHFS may explain why de novo purine biosynthesis is protected from common disruptions in the folate-dependent one-carbon network. Carbon 152-158 methenyltetrahydrofolate synthetase Homo sapiens 37-42 16360661-3 2006 The spectra acquired allow assignment of the C-linked sugar to either the C-6 or C-8 position of the aglycone and provide data on the molecular mass of the compound, the number and type of O-linked sugars and the molecular mass of the flavone aglycone. Carbon 45-46 complement C6 Homo sapiens 74-77 15456244-6 2004 Docking studies and molecular dynamics simulations, using the crystal structure of FAAH, indicated that the O-biphenyl scaffold of the carbamate inhibitors can be accommodated within a lipophilic region of the substrate-binding site, where their folded shape mimics the initial 10-12 carbon atoms of the arachidonyl moiety of anandamide (a natural FAAH substrate) and methyl arachidonyl fluorophosphonate (a nonselective FAAH inhibitor). Carbon 284-290 fatty-acid amide hydrolase-like Rattus norvegicus 83-87 15456244-6 2004 Docking studies and molecular dynamics simulations, using the crystal structure of FAAH, indicated that the O-biphenyl scaffold of the carbamate inhibitors can be accommodated within a lipophilic region of the substrate-binding site, where their folded shape mimics the initial 10-12 carbon atoms of the arachidonyl moiety of anandamide (a natural FAAH substrate) and methyl arachidonyl fluorophosphonate (a nonselective FAAH inhibitor). Carbon 284-290 fatty-acid amide hydrolase-like Rattus norvegicus 348-352 15456244-6 2004 Docking studies and molecular dynamics simulations, using the crystal structure of FAAH, indicated that the O-biphenyl scaffold of the carbamate inhibitors can be accommodated within a lipophilic region of the substrate-binding site, where their folded shape mimics the initial 10-12 carbon atoms of the arachidonyl moiety of anandamide (a natural FAAH substrate) and methyl arachidonyl fluorophosphonate (a nonselective FAAH inhibitor). Carbon 284-290 fatty-acid amide hydrolase-like Rattus norvegicus 348-352 15552415-1 2004 The double-differential cross sections for (n, px), (n, dx), (n, tx), (n, 3Hex) and (n, alphax) reactions in carbon have been measured at 96 MeV incident neutron energy. Carbon 109-115 hematopoietically expressed homeobox Homo sapiens 75-78 16360661-3 2006 The spectra acquired allow assignment of the C-linked sugar to either the C-6 or C-8 position of the aglycone and provide data on the molecular mass of the compound, the number and type of O-linked sugars and the molecular mass of the flavone aglycone. Carbon 45-46 homeobox C8 Homo sapiens 81-84 26619894-2 2015 Thus, we report a facile approach to prepare flexible papers with SnS2 nanosheets (SnS2 NSs) homogeneously dispersed and confined within the conductive graphene-carbon nanotube (CNT) hybrid frameworks. Carbon 161-167 sodium voltage-gated channel alpha subunit 11 Homo sapiens 66-70 26619894-2 2015 Thus, we report a facile approach to prepare flexible papers with SnS2 nanosheets (SnS2 NSs) homogeneously dispersed and confined within the conductive graphene-carbon nanotube (CNT) hybrid frameworks. Carbon 161-167 sodium voltage-gated channel alpha subunit 11 Homo sapiens 83-87 26437900-3 2015 Benefiting from the collaborative advantages of metallic character, 1D porous nanowire arrays, and unique 3D electrode configuration, surface oxidation activated Co4N porous nanowire arrays/carbon cloth achieved an extremely small overpotential of 257 mV at a current density of 10 mA cm(-2), and a low Tafel slope of 44 mV dec(-1) in an alkaline medium, which is the best OER performance among reported Co-based electrocatalysts to date. Carbon 190-196 deleted in esophageal cancer 1 Homo sapiens 324-330 16459223-0 2006 Vitamin E and C supplementation prevents decrease of eicosapentaenoic acid in mononuclear cells in chronic hepatitis C patients during combination therapy of interferon alpha-2b and ribavirin. Carbon 14-15 interferon alpha 2 Homo sapiens 158-177 16331442-3 2006 Results showed that the pyrolytic analyzer using pure O2 and off-line IC combined with a standard TOX carbon (coconut-based) achieved the most complete recovery of TOCl, TOBr and TOI for both model compounds and real samples. Carbon 102-108 thymocyte selection associated high mobility group box Homo sapiens 98-101 15313216-2 2004 NADP-dependent malic enzyme (NADP-ME) may be important in supplying both carbon and NADPH for fatty acid biosynthesis in the developing endosperm of the oilseed Ricinus communis. Carbon 73-79 NADP-dependent malic enzyme Ricinus communis 0-27 15313216-2 2004 NADP-dependent malic enzyme (NADP-ME) may be important in supplying both carbon and NADPH for fatty acid biosynthesis in the developing endosperm of the oilseed Ricinus communis. Carbon 73-79 NADP-dependent malic enzyme Ricinus communis 29-36 15231826-14 2004 ADH8B has the capacity to efficiently biotransform longer chain primary alcohols (>/=5 carbons) and S-hydroxymethlyglutathione, whereas ADH8A does not efficiently metabolize these substrates. Carbon 90-97 alcohol dehydrogenase 8b Danio rerio 0-5 25557321-6 2015 Among the 1,056 DEGs between SDR-H and female parent, many genes were associated with metabolic process and carbon utilization. Carbon 108-114 caveolae associated protein 2 Homo sapiens 29-32 15273745-1 2004 Carbon nanotubes (CNTs) are under intense investigation in materials science owing to their potential for modifying the electrical conductivity sigma, shear viscosity eta, and other transport properties of polymeric materials. Carbon 0-6 endothelin receptor type A Homo sapiens 167-170 15981198-6 2006 The short-chain products identified allowed inference of the radical oxidation along the linoleic acid chain by abstraction of hydrogen atoms in carbon atoms ranging from C-8 to C-14. Carbon 145-151 homeobox C8 Homo sapiens 171-182 15267233-4 2004 The transfection inhibiting role of the five-carbon spacer unit in the headgroup region of the present novel class of cationic lipids was demonstrated by both beta-galactosidase reporter gene expression and histochemical X-gal staining assays. Carbon 45-51 galactosidase beta 1 Homo sapiens 159-177 26615562-6 2015 The central C-N bond dissociation energies (BDEs) of title molecules are lower than that of PhN 5 . Carbon 12-13 carbamoyl-phosphate synthase 1 Homo sapiens 92-95 15235119-0 2004 Expression profiling-based identification of CO2-responsive genes regulated by CCM1 controlling a carbon-concentrating mechanism in Chlamydomonas reinhardtii. Carbon 98-104 uncharacterized protein Chlamydomonas reinhardtii 79-83 15209511-3 2004 Rcd-1 is evolutionarily conserved among many species, and moreover the yeast homologue CAF40 is part of the carbon catabolite repressor protein transcriptional mediator thought to be involved in the negative regulation of genes transcribed by RNA polymerase II. Carbon 108-114 CCR4-NOT transcription complex, subunit 9 Mus musculus 0-5 15182299-11 2004 We propose that glycolysis in Gpi1-negative cells proceeds entirely through the pentose phosphate pathway, creating NADPH at the cost of organic carbon. Carbon 145-151 glucose-6-phosphate isomerase 1 Mus musculus 30-34 15154810-5 2004 The metals are eta(6)-coordinated to the puckered six-membered face of the tricarbadecaboranyl cage, with the exopolyhedral substituents bonded to the low-coordinate carbon adjacent to the iron. Carbon 166-172 endothelin receptor type A Homo sapiens 5-8 15016764-4 2004 We demonstrate here that expression of the equivalent mutations in aac2-defective haploid strains of Saccharomyces cerevisiae results in (a) a marked growth defect on non-fermentable carbon sources, and (b) a concurrent reduction of the amount of mitochondrial cytochromes, cytochrome c oxidase activity and cellular respiration. Carbon 183-189 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 67-71 15034616-1 2004 In examining C-6 modified 4-nitrophenyl beta-D-galactopyranosides as donor structures the beta-galactosidase (Bacillus circulans) revealed an unexpectedly broad substrate specificity which allowed successful syntheses of various disaccharide components. Carbon 13-14 galactosidase beta 1 Homo sapiens 90-108 15075261-0 2004 Nrg1 and nrg2 transcriptional repressors are differently regulated in response to carbon source. Carbon 82-88 Nrg2p Saccharomyces cerevisiae S288C 9-13 15075261-2 2004 We show that NRG1 and NRG2 are differently regulated in response to carbon source at both the RNA and protein levels. Carbon 68-74 Nrg2p Saccharomyces cerevisiae S288C 22-26 15174275-2 2004 When yeast are grown in media containing nonfermentable carbon sources, the constitutive level of this protein increases, which suggests an association between the expression of Hsp104 and yeast energy metabolism. Carbon 56-62 chaperone ATPase HSP104 Saccharomyces cerevisiae S288C 178-184 28786676-2 2004 It has been found that the eta1-HCO species attached to a Ru atom by a single Ru-C bond is unstable, and that it will convert to more strongly bound eta2- and eta3-HCO surface species. Carbon 33-34 DNA polymerase iota Homo sapiens 149-153 15025535-3 2004 In this report, we describe a new generation of ICAT reagents that contain the following additional features: (1) a visible tag that allows the electrophoretic position of tagged peptides during separation to be easily monitored; (2) a photocleavable linker that allows most of the tag to be removed prior to mass spectrometric analysis; (3) an isotope tag that contains carbon-13 and nitrogen-15 atoms instead of deuterium to ensure precise comigration of light and heavy tagged peptides by reverse-phase HPLC. Carbon 371-377 catenin beta interacting protein 1 Homo sapiens 48-52 14645232-8 2004 The one-carbon response is distinct from the Bas1p purine biosynthesis regulon and thus represents the first example of transcriptional regulation in response to activated one-carbon status. Carbon 8-14 Bas1p Saccharomyces cerevisiae S288C 45-50 14645232-8 2004 The one-carbon response is distinct from the Bas1p purine biosynthesis regulon and thus represents the first example of transcriptional regulation in response to activated one-carbon status. Carbon 176-182 Bas1p Saccharomyces cerevisiae S288C 45-50 14561656-6 2004 However, if VEGF was given locally in the testes of animals pretreated with hCG 4 or 8 h earlier, VEGF acted in synergy with hCG to increase vascular carbon leakage by forming interendothelial cell gaps. Carbon 150-156 HLA complex group 4 Homo sapiens 76-81 14522996-11 2003 The observed enzyme-catalyzed formation of a labile 1"-acetylated-ADP-fluororibose intermediate using beta-2"-deoxy-2"-fluororibo-NAD+ supports a mechanism where, after nicotinamide-ribosyl cleavage, the carbonyl oxygen of acetylated substrate attacks the C-1" ribose to form an initial iminium adduct. Carbon 256-257 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 102-108 12943535-6 2003 Human ALDH3A1 demonstrated high substrate specificity for medium-chain (6 carbons and more) saturated and unsaturated aldehydes, including 4-hydroxy-2-nonenal, which are generated by the peroxidation of cellular lipids. Carbon 74-81 aldehyde dehydrogenase 3 family member A1 Homo sapiens 6-13 12855560-6 2003 C-18 bound directly to human CCR5, and this interaction was partially competed by the beta-chemokine macrophage inflammatory protein 1 beta (MIP-1 beta) and by HIV-1 R5 gp120. Carbon 0-1 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 169-174 12827295-8 2003 Using a series of polyamine analogues, it was found that the most potent inducers of PAOh1/SMO possessed multiple three-carbon linkers between nitrogens, as typified by N1,N11-bis(ethyl)norspermine. Carbon 120-126 spermine oxidase Homo sapiens 85-90 14615971-10 2003 Following deglycosylation, C-6 substitution was verified by two-dimensional correlation NMR spectroscopy, indicating that the initial adducts were formed by Michael addition of dGuo-N1 to the terminal vinyl carbon followed by cyclization to the 1,N(2)-propano structure. Carbon 207-213 complement C6 Homo sapiens 27-30 14594271-1 2003 We present a new synthesis route for nitrogen doped carbon nanotubes (CNx) based on the aerosol method. Carbon 52-58 calnexin Homo sapiens 70-73 12799364-2 2003 However, yeast strains disrupted at the FMT1 locus, encoding mitochondrial methionyl-tRNA formyltransferase, lack detectable fMet-tRNAfMet but exhibit normal mitochondrial function as evidenced by normal growth on non-fermentable carbon sources. Carbon 230-236 methionyl-tRNA formyltransferase Saccharomyces cerevisiae S288C 40-44 12774903-6 2003 When soluble organic carbon was removed, ORP7 (redox potential rectified to pH at 7) were around -120 or +260 mV. Carbon 21-27 oxysterol binding protein like 7 Homo sapiens 41-45 12774903-7 2003 When soluble organic carbon increased due to organic overload, ORP7 was around +30 mV. Carbon 21-27 oxysterol binding protein like 7 Homo sapiens 63-67 16256594-11 2003 Compared with chemically activated carbons using K(2)CO(3), the porous properties of the physically activated carbons have lower S(BET) and V(P) values because of the smaller size and lower volume of their micropores. Carbon 110-117 delta/notch like EGF repeat containing Homo sapiens 131-134 12753928-5 2003 Here we show that the plasmid encoding C. elegans CLK-1 supported aerobic respiration on a non-fermentable carbon source of E. coli ubiF mutant strain and rescued the ability to synthesize ubiquinone, suggesting that the eukaryotic CLK-1/Coq7p family could function as bacterial UbiF. Carbon 107-113 5-demethoxyubiquinone hydroxylase, mitochondrial Caenorhabditis elegans 50-55 12651128-6 2003 Carbon-mineral adsorbents of different specific surface areas (S(BET) from 17.6 to 153 m(2)/g) and pore volumes (from 0.035 to 0.093 cm(3)/g) were prepared. Carbon 0-6 delta/notch like EGF repeat containing Homo sapiens 65-68 12765255-5 2003 The carbon content of plant was 1328649 for the total and 13.78 t/hm2 for the mean, and amounts of carbon fixed and oxygen made by urban vegetation were respectively 4.80 t/(hm2 x a) and 12.79 t/(hm2 x a) for the mean and 462624 t/a and 1232430 t/a for the total, which were equal to 1.45 times and 1.04 times of those by human breathing. Carbon 4-10 cholinergic receptor muscarinic 2 Homo sapiens 66-69 12765255-5 2003 The carbon content of plant was 1328649 for the total and 13.78 t/hm2 for the mean, and amounts of carbon fixed and oxygen made by urban vegetation were respectively 4.80 t/(hm2 x a) and 12.79 t/(hm2 x a) for the mean and 462624 t/a and 1232430 t/a for the total, which were equal to 1.45 times and 1.04 times of those by human breathing. Carbon 99-105 cholinergic receptor muscarinic 2 Homo sapiens 174-177 12765255-5 2003 The carbon content of plant was 1328649 for the total and 13.78 t/hm2 for the mean, and amounts of carbon fixed and oxygen made by urban vegetation were respectively 4.80 t/(hm2 x a) and 12.79 t/(hm2 x a) for the mean and 462624 t/a and 1232430 t/a for the total, which were equal to 1.45 times and 1.04 times of those by human breathing. Carbon 99-105 cholinergic receptor muscarinic 2 Homo sapiens 174-177 12644298-10 2003 Interestingly, cortisol produces a much weaker N/C-interaction than aldosterone, and it is possible that the N/C-interaction may contribute to observed functional differences in the MR bound to the two ligands. Carbon 49-50 nuclear receptor subfamily 3 group C member 2 Homo sapiens 182-184 12576646-6 2003 Insertion of a carbon chain between the imino carbon and the carboxyl moiety of (Z)-2-(4-[(5-methyl-2-phenyl-1, 3-oxazol-4-yl)methoxy]benzyloxyimino)-2-phenylacetic acid (2) resulted in a marked increase in transcriptional activity at PPARgamma. Carbon 15-21 peroxisome proliferator activated receptor gamma Mus musculus 235-244 12554867-7 2003 Interestingly, edc1Delta strains show defects in utilization of glycerol as a carbon source and misregulation of several mRNAs in response to carbon-source changes. Carbon 78-84 alpha-1-microglobulin/bikunin precursor Homo sapiens 15-19 12554867-7 2003 Interestingly, edc1Delta strains show defects in utilization of glycerol as a carbon source and misregulation of several mRNAs in response to carbon-source changes. Carbon 142-148 alpha-1-microglobulin/bikunin precursor Homo sapiens 15-19 12554867-8 2003 This identifies a critical role for decapping and Edc1p in alterations of gene expression in response to carbon-source changes. Carbon 105-111 alpha-1-microglobulin/bikunin precursor Homo sapiens 50-55 15058183-2 2003 In Saccharomyces cerevisiae the plasma membrane proteins Ras1 and Ras2 are sensing the nutritional status of the environments, e.g., the abundance and quality of available carbon sources. Carbon 172-178 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 66-70 16228369-1 2003 This minireview focuses on the mechanism of inorganic carbon uptake in cyanobacteria and in particular the two CO(2)-uptake systems and two bicarbonate transporters recently identified in Synechocycstis PCC 6803, and their presence in other cyanobacterial strains. Carbon 54-60 crystallin gamma D Homo sapiens 203-206 16292676-2 2006 Here, we show that a RAS2(val19) mutant that exhibits elevated levels of Ras/PKA signaling activity is unable to grow on media with galactose as the sole source of carbon. Carbon 164-170 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 21-25 16289480-0 2006 Structural-activity relationship study on C-4 carbon atom of the CB1 antagonist SR141716: synthesis and pharmacological evaluation of 1,2,4-triazole-3-carboxamides. Carbon 46-52 cannabinoid receptor 1 (brain) Mus musculus 65-68 16972021-1 2006 The monitoring of the blood concentration at 2 h (C(2)) after the oral administration of a cyclosporine (CsA) microemulsion was reconfirmed to be useful for the prediction of systemic exposure, the area under the blood concentration-time curve from 0 to 4 h (AUC(0-4)), in a group of Japanese patients, consisting of 33 children aged 5-15 years and 19 young adults aged 16-27 years, with a greater correlation for C(2) (r = 0.927) than the trough concentration (r = 0.488). Carbon 50-51 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 105-108 16336970-4 2005 Mrg19 is a putative transcription factor that regulates carbon and nitrogen metabolism in yeast. Carbon 56-62 Csr2p Saccharomyces cerevisiae S288C 0-5 16291721-10 2005 Release is likely due to the exclusive use of C-14:0 myristate in the bloodstream stage GPI anchor. Carbon 46-47 glucose-6-phosphate isomerase Homo sapiens 88-91 16260593-3 2005 The carbon source-regulated effect on MFA2 3"-UTR-controlled translation involves the role of conserved ARE binding proteins, the ELAV/TIA-1-like Pub1p, which can interact with the cap/eIF4G complex, and the translation/mRNA stability factor poly(A) binding protein (Pab1p). Carbon 4-10 Pub1p Saccharomyces cerevisiae S288C 146-151 16260593-4 2005 Pub1p binds the MFA2 3"-UTR in a p38 MAPK/Hog1p-regulated manner in response to carbon source growth conditions. Carbon 80-86 Pub1p Saccharomyces cerevisiae S288C 0-5 16260593-8 2005 Importantly, Pab1p binds the MFA2 3"-UTR only in a PUB1 strain, and correlating with this requirement, Pub1p controls translation repression of MFA2 in a carbon source/Hog1p-regulated manner. Carbon 154-160 Pub1p Saccharomyces cerevisiae S288C 51-55 16260593-8 2005 Importantly, Pab1p binds the MFA2 3"-UTR only in a PUB1 strain, and correlating with this requirement, Pub1p controls translation repression of MFA2 in a carbon source/Hog1p-regulated manner. Carbon 154-160 Pub1p Saccharomyces cerevisiae S288C 103-108 16202243-8 2005 Fermentable carbon sources, such as glucose (at low concentrations), lactose and sucrose, as a sole carbon source, enhanced the synthesis of beta-galactosidase from the GGTII-lacZ fusion gene in wildtype KP1 cells but not in Pap1-negative cells. Carbon 12-18 galactosidase beta 1 Homo sapiens 141-159 16033762-7 2005 The effect of amisyn was further characterized using carbon fiber amperometry in chromaffin cells. Carbon 53-59 syntaxin binding protein 6 Rattus norvegicus 14-20 16173582-1 2005 A novel method determining compound-specific carbon isotopic compositions for atmospheric formaldehyde and acetaldehyde in ppb or sub-ppb levels by gas chromatography/ combustion/isotope ratio mass spectrometry (GC/C/ IRMS) is presented. Carbon 45-51 guanylate cyclase 2C Homo sapiens 212-216 16132698-5 2005 In the present study the effect of carbon ion irradiation on p 44/42 MAPK and NF-kappaB, which are essentially survival factors, have been studied. Carbon 35-41 interferon induced protein 44 Homo sapiens 61-65 15911615-3 2005 PLP synthase is a heteromeric glutamine amidotransferase in which PdxT produces ammonia from glutamine and PdxS combines ammonia with five- and three-carbon phosphosugars to form PLP. Carbon 150-156 pyridoxal phosphatase Homo sapiens 0-3 15925607-3 2005 Group I corncob-derived activated carbons, with KOH/char ratios from 0.5 to 2, exhibited BET surface area ranging from 841 to 1221 m(2)/g. Carbon 34-41 delta/notch like EGF repeat containing Homo sapiens 89-92 15925607-4 2005 Group II corncob-derived activated carbons, with KOH/char rations from 3 to 6, showed high BET surface areas, from 1976 to 2595 m(2)/g. Carbon 35-42 delta/notch like EGF repeat containing Homo sapiens 91-94 15983642-1 2005 Fluorinated single walled carbon nanotubes (SWNTs) undergo a facile Diels-Alder [4 + 2] cycloaddition with a range of dienes resulting in a C ratio substituent ratio between 20 ratio 1 to 32 ratio 1; IR, Raman, AFM and (13)C NMR characterization are consistent with sidewall functionalization. Carbon 26-32 afamin Homo sapiens 211-214 16034819-7 2005 The transcriptional regulation of this gene by the carbon source was further confirmed when the alpha-amylase gene from Bacillus subtilis was placed under the control of P(PGK1): higher levels of expression were obtained when cells were grown on glucose as compared to glycerol and methanol. Carbon 51-57 phosphoglycerate kinase Saccharomyces cerevisiae S288C 172-176 15994921-5 2005 The distinctive differences in metabolic profiles of K12 and K13 codon mutated cells indicate that a strong correlation exists between the flow of glucose carbons towards either increased anaerobic glycolysis, and resistance to apoptosis (K12), or increased macromolecule synthesis, rapid proliferation, and increased sensitivity to apoptosis. Carbon 155-162 keratin 13 Mus musculus 61-64 15879504-6 2005 Altogether, our results indicate that Not4p is a pivotal factor involved in the regulation of carbon metabolism in yeast. Carbon 94-100 CCR4-NOT core ubiquitin-protein ligase subunit MOT2 Saccharomyces cerevisiae S288C 38-43 15764712-5 2005 Five metabolites were detected in the metabolism of C3O1 and O2C3 by human CYP24A1 including both C-23 and C-24 oxidation pathways. Carbon 52-53 nucleolin Homo sapiens 98-102 16833760-11 2005 On the other hand, an RRKM-master equation analysis shows that hot alpha-hydroxy-alkylperoxyls formed by the addition of O(2) to C(1)-, C(2)-, and C(3)-alpha-hydroxy-alkyl radicals will quasi-uniquely fragment to HO2* plus the carbonyl under all atmospheric conditions. Carbon 129-130 heme oxygenase 2 Homo sapiens 213-216 16833760-11 2005 On the other hand, an RRKM-master equation analysis shows that hot alpha-hydroxy-alkylperoxyls formed by the addition of O(2) to C(1)-, C(2)-, and C(3)-alpha-hydroxy-alkyl radicals will quasi-uniquely fragment to HO2* plus the carbonyl under all atmospheric conditions. Carbon 136-137 heme oxygenase 2 Homo sapiens 213-216 16852150-9 2005 Although the XPS data shows carbon present at the Ag(111) surface after exposure to PhI, no features attributable to phenyl groups were observed by STM. Carbon 28-34 glucose-6-phosphate isomerase Homo sapiens 84-87 15780659-2 2005 One such system, the target of rapamycin (Tor) proteins, senses nutrients and uses the GATA activators Gln3p and Nil1p to regulate translation in response to low-quality carbon and nitrogen. Carbon 170-176 Gat1p Saccharomyces cerevisiae S288C 113-118 15780659-4 2005 When carbon and nitrogen are abundant, the phosphorylated Ure2p anchors the also phosphorylated Gln3p and Nil1p in the cytoplasm. Carbon 5-11 Gat1p Saccharomyces cerevisiae S288C 106-111 15813743-0 2005 The gene NCE103 (YNL036w) from Saccharomyces cerevisiae encodes a functional carbonic anhydrase and its transcription is regulated by the concentration of inorganic carbon in the medium. Carbon 77-83 carbonate dehydratase NCE103 Saccharomyces cerevisiae S288C 9-15 15732990-3 2005 In contrast, the corresponding reaction of [Rh(H)2(PPhMe2)2(acetone)2]PF6 with acetophenone semicarbazone gives the ortho-metalated-semicarbazone species cis-[RhH(PPhMe2)2{o-C6H4(Me)C=N-N(H)CONH2}]PF6. Carbon 174-175 sperm associated antigen 17 Homo sapiens 70-73 15865206-8 2005 And shifts to sucrose (0.2, 0.4, 0.8 or 1.6%) as a sole carbon source markedly enhanced the synthesis of beta-galactosidase from the Grx2-lacZ fusion gene, the degree of which was inversely dependent on concentration. Carbon 56-62 dithiol glutaredoxin GRX2 Saccharomyces cerevisiae S288C 133-137 15865206-9 2005 However, nonfermentable carbon sources reduced the expression of the Grx2 gene due to their growth arrest. Carbon 24-30 dithiol glutaredoxin GRX2 Saccharomyces cerevisiae S288C 69-73 15865206-12 2005 Our results indicate that the Grx2 protein, located in the nucleus, is linked with the yeast growth, and that the gene is regulated by carbon sources. Carbon 135-141 dithiol glutaredoxin GRX2 Saccharomyces cerevisiae S288C 30-34 15701796-6 2005 Complete deletion of RSM28 caused only a modest decrease in growth on nonfermentable carbon sources in otherwise wild-type strains and enhanced the respiratory defect of the suppressible cox2 mutations. Carbon 85-91 mitochondrial 37S ribosomal protein RSM28 Saccharomyces cerevisiae S288C 21-26 15704215-6 2005 In consonance with this, expression of LGT1 in S. cerevisiae was high in media containing 4% of glucose and almost undetectable in galactose as sole carbon source. Carbon 149-155 hexose transporter HXT4 Saccharomyces cerevisiae S288C 39-43 15595850-8 2004 The results identify CarB as a particularly interesting member of the crotonase superfamily that combines in one net reaction three activities of this superfamily, decarboxylation, C-C bond formation, and CoA ester hydrolysis. Carbon 181-182 syntaxin 8 Homo sapiens 21-25 15568107-1 2004 Carbon capsules with hollow core and mesoporous shell (HCMS) structures were used as a support material for Pt(50)-Ru(50) catalyst, and the catalytic performance of the HCMS supported catalyst in the direct methanol fuel cell was described; the HCMS carbon supported catalysts exhibited much higher specific activity for methanol oxidation than the commonly used E-TEK catalyst by about 80%, proving that the HCMS carbon capsules are an excellent support for electrode catalysts in DMFC. Carbon 0-6 TEK receptor tyrosine kinase Homo sapiens 365-368 15607962-0 2004 Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation. Carbon 2-3 myelocytomatosis oncogene Mus musculus 34-37 15607962-0 2004 Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation. Carbon 2-3 myelocytomatosis oncogene Mus musculus 99-102 15563183-0 2004 Michael addition reactions with eta2-coordinated anisoles: controlling the stereochemistry of the para and benzylic carbons. Carbon 116-123 DNA polymerase iota Homo sapiens 32-36 15630560-2 2004 The methodology is applied to protein L and malate synthase G. Average (13)C CSA values are considerably smaller for Ile than Leu/Val (17 vs 25 ppm) and are in good agreement with previous solid state NMR studies of powders of amino acids and dipeptides and in reasonable agreement with quantum-chemical DFT calculations of methyl carbon CSA values in peptide fragments. Carbon 331-337 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 77-80 15583265-2 2004 The test uses the principle of lateral flow through a nitrocellulose strip of the sample mixed with a colloidal carbon conjugate of a monoclonal antibody specific for Schistosoma circulating cathodic antigen (CCA). Carbon 112-118 fibrillin 2 Homo sapiens 167-213 15971344-4 2004 The research programs associated with ETOILE concern mainly the tracking of moving organs, the design of an in-beam PET detector, the simulation of the interaction of carbon ions with tissues and radiobiological studies on the radiosensitivity and tolerance of normal tissues and on the radioresistance of tumours. Carbon 167-173 KH RNA binding domain containing, signal transduction associated 3 Homo sapiens 38-44 15521774-1 2004 The sterically crowded (C(5)Me(5))(3)U complex reacts with KC(8) or K/(18-crown-6) in benzene to form [(C(5)Me(5))(2)U](2)(mu-eta(6):eta(6)-C(6)H(6)), 1, and KC(5)Me(5). Carbon 24-25 endothelin receptor type A Homo sapiens 126-129 15521774-1 2004 The sterically crowded (C(5)Me(5))(3)U complex reacts with KC(8) or K/(18-crown-6) in benzene to form [(C(5)Me(5))(2)U](2)(mu-eta(6):eta(6)-C(6)H(6)), 1, and KC(5)Me(5). Carbon 24-25 endothelin receptor type A Homo sapiens 133-136 15543751-4 2004 Sediment treated with 3.4 wt % activated carbon showed 92% and 84% reductions in aqueous equilibrium PCB and PAH concentrations, 77% and 83% reductions in PCB and PAH uptake by semipermeable membrane devices (SPMD), respectively, and reductions in PCB flux to overlying water in quiescent systems up to 89%. Carbon 41-47 phenylalanine hydroxylase Homo sapiens 109-112 15543751-4 2004 Sediment treated with 3.4 wt % activated carbon showed 92% and 84% reductions in aqueous equilibrium PCB and PAH concentrations, 77% and 83% reductions in PCB and PAH uptake by semipermeable membrane devices (SPMD), respectively, and reductions in PCB flux to overlying water in quiescent systems up to 89%. Carbon 41-47 phenylalanine hydroxylase Homo sapiens 163-166 15453723-2 2004 Our new artificial acylase, tert-butyldiphenylsilyl ether of N-(2,4,6-triisopropylbenzenesulfonyl)-pi(Me)-l-histidinol, is a simple and small molecule (molecular weight = 660) that contains only one chiral carbon center that originates from natural l-histidine. Carbon 206-212 aminoacylase 1 Homo sapiens 19-26 12458543-0 2002 trans-Addition of two carbon substituents across a benzene double bond in [(eta6-benzene)Mo(CO)3]. Carbon 22-28 endothelin receptor type A Homo sapiens 76-79 12459473-0 2002 Antisense down regulation of NtBI-1 in tobacco BY-2 cells induces accelerated cell death upon carbon starvation. Carbon 94-100 bax inhibitor 1-like Nicotiana tabacum 29-35 12523505-6 2002 Experimental results showed that steam was sightly more effective than nitrogen at regenerating the total micropore volume and BET surface area of the carbons. Carbon 151-158 delta/notch like EGF repeat containing Homo sapiens 127-130 12423629-6 2002 GH restored the serum IGF-I levels in Dex treated animals, but caused further increases in proteasome subunit mRNAs (C-2, 35%; C-3, 34.5%; C-8, 33%; C-6, 42%; C-5, 32%; C-9, 37%). Carbon 117-118 gonadotropin releasing hormone receptor Rattus norvegicus 0-2 12423629-8 2002 Surprisingly, injection of GH alone in normal animals increased proteasome subunit mRNAs in skeletal muscle (C-2, 85%; C-3, 109%; C-8, 91%). Carbon 109-110 gonadotropin releasing hormone receptor Rattus norvegicus 27-29 26488423-4 2015 Simultaneously, highly porous activated carbon with a high BET surface area was recovered. Carbon 40-46 delta/notch like EGF repeat containing Homo sapiens 59-62 12683671-1 2002 Ten bis-beta-carboline 1, 2 and bis-3,4-dihydro-beta-carboline 3, 4 derivatives, linked between carbons 1 and 1" by a polymethylene spacer, were synthesized from bistryptamine amides 9, 10. Carbon 96-103 beta-carboline-induced seizures 3 Mus musculus 32-37 16701529-5 2004 Through anoxic operation the poly-P bacteria are capable of removing NO(3)-N using VFA, COD as carbon source and NO(3)-N as the electron acceptor after methanogenesis has been completed. Carbon 95-101 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 88-91 25893566-7 2015 Altogether, our data show intricate genetic interactions between one-carbon units, purine and methionine metabolism through fine-tuning of serine hydroxymethyltransferase by AICAR and the transcription factor Bas1. Carbon 69-75 Bas1p Saccharomyces cerevisiae S288C 209-213 15269223-7 2004 The pem1 pem2Delta cells will also grow without choline, in the presence of Prn, on nonfermentable carbon sources (requiring functional mitochondria) and accumulate nearly 70% of their phospholipid as hexagonal phase-forming types. Carbon 99-105 phosphatidylethanolamine N-methyltransferase Saccharomyces cerevisiae S288C 4-8 15220348-8 2004 FAR1 preferred saturated and unsaturated fatty acids of 16 or 18 carbons as substrates, whereas FAR2 preferred saturated fatty acids of 16 or 18 carbons. Carbon 65-72 fatty acyl-CoA reductase 1 Homo sapiens 0-4 15220348-8 2004 FAR1 preferred saturated and unsaturated fatty acids of 16 or 18 carbons as substrates, whereas FAR2 preferred saturated fatty acids of 16 or 18 carbons. Carbon 145-152 fatty acyl-CoA reductase 2 Homo sapiens 96-100 15358094-3 2004 These results indicate that the orientation of the hydroxyl group at the C-3 position determines the ratio between C-23 and C-24 oxidation pathways. Carbon 73-74 nucleolin Homo sapiens 115-119 15347746-7 2004 However, CDC25 is essential for growth in galactose, in non-fermentable carbon sources and under continuous incubation at 38 degrees C. In conclusion, the function of the catalytic, C-terminal domain of Cdc25p is not only important for fermentative growth, but also for growth in non-fermentable carbon sources and to trigger galactose derepression. Carbon 72-78 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 9-14 15347746-7 2004 However, CDC25 is essential for growth in galactose, in non-fermentable carbon sources and under continuous incubation at 38 degrees C. In conclusion, the function of the catalytic, C-terminal domain of Cdc25p is not only important for fermentative growth, but also for growth in non-fermentable carbon sources and to trigger galactose derepression. Carbon 72-78 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 203-209 15347746-7 2004 However, CDC25 is essential for growth in galactose, in non-fermentable carbon sources and under continuous incubation at 38 degrees C. In conclusion, the function of the catalytic, C-terminal domain of Cdc25p is not only important for fermentative growth, but also for growth in non-fermentable carbon sources and to trigger galactose derepression. Carbon 296-302 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 9-14 15347746-7 2004 However, CDC25 is essential for growth in galactose, in non-fermentable carbon sources and under continuous incubation at 38 degrees C. In conclusion, the function of the catalytic, C-terminal domain of Cdc25p is not only important for fermentative growth, but also for growth in non-fermentable carbon sources and to trigger galactose derepression. Carbon 296-302 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 203-209 15208340-7 2004 Aside from the sulphur-specific regulation, the induction of SULTR1;1 and SULTR1;2 high-affinity sulphate transporters by sulphur limitation was dependent on the supply of carbon and nitrogen. Carbon 172-178 sulfate transporter 1;2 Arabidopsis thaliana 74-82 15252576-3 2004 It was found that the diyne ligand easily reacts with all these complexes to give [HOs(3)(CO)8(PR3)-[mu3, eta1:eta3:eta1)-(CH(3)-C-C=CH-CH=C-O)]] complexes (V, VI and VII, respectively) containing the "Os3C3" pentagonal pyramid cluster framework. Carbon 90-91 proteinase 3 Homo sapiens 95-98 15252576-3 2004 It was found that the diyne ligand easily reacts with all these complexes to give [HOs(3)(CO)8(PR3)-[mu3, eta1:eta3:eta1)-(CH(3)-C-C=CH-CH=C-O)]] complexes (V, VI and VII, respectively) containing the "Os3C3" pentagonal pyramid cluster framework. Carbon 123-124 proteinase 3 Homo sapiens 95-98 15252576-5 2004 In the case of the PEt(3) substituted cluster the second hydride transfer onto the organic fragment occurs to afford the nonhydride [Os(3)(CO)(8)(PR3)[mu3), eta1:eta2:eta1)-(CH(3)-CH-C=CH-CH=C-O)]] cluster, VIII, containing distorted pentagonal pyramid framework with a broken Os-C bond. Carbon 139-140 proteinase 3 Homo sapiens 146-149 15252576-5 2004 In the case of the PEt(3) substituted cluster the second hydride transfer onto the organic fragment occurs to afford the nonhydride [Os(3)(CO)(8)(PR3)[mu3), eta1:eta2:eta1)-(CH(3)-CH-C=CH-CH=C-O)]] cluster, VIII, containing distorted pentagonal pyramid framework with a broken Os-C bond. Carbon 139-140 DNA polymerase iota Homo sapiens 162-166 15252576-5 2004 In the case of the PEt(3) substituted cluster the second hydride transfer onto the organic fragment occurs to afford the nonhydride [Os(3)(CO)(8)(PR3)[mu3), eta1:eta2:eta1)-(CH(3)-CH-C=CH-CH=C-O)]] cluster, VIII, containing distorted pentagonal pyramid framework with a broken Os-C bond. Carbon 139-140 cytochrome c oxidase subunit 8A Homo sapiens 207-211 15022203-2 2004 The method is based on the fact that the carbon chemical shifts in the isotropic phase and in the oriented phase under static and off-magic angle spinning (OMAS) conditions are uniquely related by the tensorial property of the CSA tensor, requiring just one OMAS spectrum and the assignment in the isotropic phase. Carbon 41-47 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 227-230 14966266-3 2004 The Sip1 beta subunit resides in the cytosol in glucose-grown cells and relocalizes to the vacuolar membrane in response to carbon stress. Carbon 124-130 Sip1p Saccharomyces cerevisiae S288C 4-8 15143799-8 2004 The latter descriptor was found to be an important factor in explaining the experimentally observed selectivity towards the methylation of the C-4", C-6, C-11 and C-12 anions. Carbon 143-144 complement C6 Homo sapiens 149-152 17265611-7 2004 The study showed that by the end of Ramadan fasting, there was a significant improvement in the mean levels of hemoglobin (Hb), TC, TG, HDL-c, LDL-c, TC/HDL, LDL/HDL, Lp (a), APA, APB, PT and systolic (SBP) and diastolic blood pressure (DBP) that persisted for four weeks after fasting (P < 0.05). Carbon 72-73 selenium binding protein 1 Homo sapiens 202-205 12431101-2 2002 TNA is derived from a sugar containing only four carbon atoms and is one of the simplest potentially natural nucleic acid alternatives investigated thus far in the context of a chemical etiology of nucleic acid structure. Carbon 49-55 C-type lectin domain family 3 member B Homo sapiens 0-3 12540091-0 2002 Electroadsorption of acilan blau dye from textile effluents by using activated carbon-perlite mixtures. Carbon 79-85 nucleotide binding oligomerization domain containing 2 Homo sapiens 28-32 12324700-3 2002 In both 3-nitrobenzylidene-3"-iodoaniline and 4-nitrobenzylidene-3"-iodoaniline, (V) and (VI), a combination of C-H...O hydrogen bonds and iodo...nitro interactions generates molecular ladders that are linked into sheets by aromatic pi...pi stacking interactions, while in 2-nitrobenzylidene-4"-iodoaniline and 3-nitrobenzylidene-4"-iodoaniline, (VII) and (VIII), which both crystallize with Z" = 2 in C2/c and P1, respectively, the combination of C-H...O hydrogen bonds and iodo...nitro interactions generates sheets, which in (VIII) are further linked by pi...pi stacking interactions to form a three-dimensional structure. Carbon 112-113 cytochrome c oxidase subunit 8A Homo sapiens 357-361 12324700-3 2002 In both 3-nitrobenzylidene-3"-iodoaniline and 4-nitrobenzylidene-3"-iodoaniline, (V) and (VI), a combination of C-H...O hydrogen bonds and iodo...nitro interactions generates molecular ladders that are linked into sheets by aromatic pi...pi stacking interactions, while in 2-nitrobenzylidene-4"-iodoaniline and 3-nitrobenzylidene-4"-iodoaniline, (VII) and (VIII), which both crystallize with Z" = 2 in C2/c and P1, respectively, the combination of C-H...O hydrogen bonds and iodo...nitro interactions generates sheets, which in (VIII) are further linked by pi...pi stacking interactions to form a three-dimensional structure. Carbon 112-113 cytochrome c oxidase subunit 8A Homo sapiens 529-533 12529962-2 2002 In the murine colon-26 (C-26) adenocarcinoma model IL-1, secreted by tumor-infiltrating mononuclear phagocytes, has an important role in induction of cancer cachexia. Carbon 24-25 interleukin 1 complex Mus musculus 51-55 12369205-6 2002 Histidyl-phosphorylated HPr (HPr-his P) is required for the transport of many carbon sources by the phosphotransferase system (PTS). Carbon 78-84 haptoglobin-related protein Homo sapiens 24-27 12369205-6 2002 Histidyl-phosphorylated HPr (HPr-his P) is required for the transport of many carbon sources by the phosphotransferase system (PTS). Carbon 78-84 haptoglobin-related protein Homo sapiens 29-38 12369205-8 2002 Thus, the ratio of HPr-his P/HPr-ser-P determines utilisation of a particular carbon source. Carbon 78-84 haptoglobin-related protein Homo sapiens 19-28 12369205-8 2002 Thus, the ratio of HPr-his P/HPr-ser-P determines utilisation of a particular carbon source. Carbon 78-84 haptoglobin-related protein Homo sapiens 19-22 12432922-1 2002 Arachidonate 12-lipoxygenase introduces a molecular oxygen at carbon 12 of arachidonic acid to generate a 12-hydroperoxy derivative. Carbon 62-71 arachidonate 12-lipoxygenase, 12S type Homo sapiens 0-28 12616689-2 2002 To increase the carbon flux through the carotenoid biosynthetic pathway, the 1658-bp region of the HMG1 gene encoding the catalytic domain (cHMG1) of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase of Saccharomyces cerevisiae was expressed in N. crassa under control of the strong, constitutive glyceraldehyde-3-phosphate dehydrogenase (GPD) promoter and the inducible alcohol dehydrogenase (alcA) promoter. Carbon 16-22 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 Saccharomyces cerevisiae S288C 99-103 12036373-5 2002 Furthermore, increasing the 23-membered lactam ring of 1 by one carbon atom (succinyl --> glutaric acid linker) gives a highly selective and potent antagonist 9 for the hMC3 receptor. Carbon 64-70 melanocortin 3 receptor Homo sapiens 172-176 12091723-0 2002 C : N ratio increases in the phloem sap during floral transition of the long-day plants Sinapis alba and Arabidopsis thaliana. Carbon 0-1 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 36-39 12091723-3 2002 In both species, the C : N ratio of the phloem sap increased markedly and early during the inductive treatment, suggesting that an inequality in organic C and N supply to the apical meristem may be important at floral transition. Carbon 21-22 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 47-50 12094292-5 2002 The inhibitory activity of Na-SP was the strongest when compared to that of heparan sulfate, heparin, dextran sulfate, dermatan sulfate, chondroitin sulfate A/C and hyaluronan. Carbon 159-160 nuclear autoantigenic sperm protein Bos taurus 27-32 11870867-6 2002 This methodology was first tested on the CcP:iso-1-cyt c complex, in which the complex with the lowest CHARMM energy has an RMSD from the crystal structure of only 1.8 A (C(alpha) carbon atoms). Carbon 180-186 LOC104968582 Bos taurus 51-56 12092568-4 2002 For the purpose of this work, a number of carbons were produced, characterised for their BET surface area and analysed for their inorganic composition. Carbon 42-49 delta/notch like EGF repeat containing Homo sapiens 89-92 11870859-9 2002 Certain ire1 strains produced significant numbers of transformants that were unable to utilize galactose as sole carbon source. Carbon 113-119 bifunctional endoribonuclease/protein kinase IRE1 Saccharomyces cerevisiae S288C 8-12 12005057-1 2002 A major part of the palmitic acid (C16:0) generated by fatty acid synthase is converted into stearic acid (C18:0) via carbon chain elongation. Carbon 118-124 fatty acid synthase Rattus norvegicus 55-74 11904149-1 2002 The yeast high-affinity glucose transporters Hxt6p and Hxt7p are rapidly degraded during nitrogen starvation in the presence of high concentrations of fermentable carbon sources. Carbon 163-169 hexose transporter HXT7 Saccharomyces cerevisiae S288C 55-60 11814438-1 2002 Introduction of a stereodefined methyl group at the C-6 position of N-acetylglucosamine mono- and disaccharides creates a strong and predictable orientational bias on the geminal C-6 hydroxyl in solution, as determined by (1)H-(1)H and (13)C-(1)H NMR coupling constants. Carbon 52-53 complement C6 Homo sapiens 179-182 11814448-10 2002 By using different cross polarisation times, the resonances of the two methyl groups and C-6 carbons can easily be distinguished. Carbon 93-100 complement C6 Homo sapiens 89-92 11856004-1 2002 A new example of magnetic nonequivalence of chemically equivalent atoms is identified from the proton and carbon resonance spectra of 9,10-di(9,9-dioctylfluorenyl)anthracene with the aid of its conformation in the crystalline state. Carbon 106-112 activation induced cytidine deaminase Homo sapiens 183-186 11849043-4 2002 Relative to control cells, those expressing GSTA1-1 showed the highest rate (about 50-fold increase) to perform GSH-conjugation of (-)-anti-DBPDE (R-absolute configuration at the benzylic oxirane carbon in the fjord-region) followed by GSTM1-1 (25-fold increase) and GSTP1-1 (10-fold increase). Carbon 196-202 glutathione S-transferase alpha 1 Homo sapiens 44-51 11948822-1 2002 The application of a combined gas chromatography-combustion/isotope ratio mass spectrometry (GC-C/IRMS) method for stable carbon isotope analysis of amino acid enantiomers in soil samples is presented. Carbon 122-128 guanylate cyclase 2C Homo sapiens 93-97 11551194-12 2001 These results suggest that the extraordinary specificity of NxTX for Kv1.3 over maxi-K channels is controlled, in part, by the toxin alpha-carbon backbone. Carbon 139-145 potassium voltage-gated channel subfamily A member 3 Homo sapiens 69-74 11522833-4 2001 We report here that if strains containing the truncated RPM2 allele are created and maintained on respiratory carbon sources they have wild-type mitochondrial genomes, and a significant portion of tRNA transcripts are processed. Carbon 110-116 ribonuclease P Saccharomyces cerevisiae S288C 56-60 11470528-0 2001 Molecular characterization of CLPT1, a SEC4-like Rab/GTPase of the phytopathogenic fungus Colletotrichum lindemuthianum which is regulated by the carbon source. Carbon 146-152 Rab family GTPase SEC4 Saccharomyces cerevisiae S288C 39-43 11385677-0 2001 Mechanistic Rationale of a Palladium-Catalyzed Allylic Substitution Polymerization-Carbon-Carbon Bond-Forming Polycondensation out of Stoichiometric Control by Cascade Bidirectional Allylation This work was supported by a Grant-in-Aid for Scientific Research (No. Carbon 83-89 activation induced cytidine deaminase Homo sapiens 231-234 11385677-0 2001 Mechanistic Rationale of a Palladium-Catalyzed Allylic Substitution Polymerization-Carbon-Carbon Bond-Forming Polycondensation out of Stoichiometric Control by Cascade Bidirectional Allylation This work was supported by a Grant-in-Aid for Scientific Research (No. Carbon 90-96 activation induced cytidine deaminase Homo sapiens 231-234 26172956-6 2015 The median beta-glucuronidase activity (measured in nanomoles of 4-methylumbelliferone (4-MU)/mL BALF/h) was 246.4 in C+ (interquartile range: 71.2-751) and 21.9 in C- (4.0-40.8) (P < 0.001). Carbon 118-119 glucuronidase beta Homo sapiens 11-29 11322734-5 2001 Reactivity of the polysaccharide C-atoms was determined by 13C NMR spectroscopy: For dextran this was C-3 > C-2 > C-4, while for pullulan it was C-6 > C-3 > C-2 > C-4. Carbon 33-34 complement C6 Homo sapiens 151-154 26374121-3 2015 The fam1 disrupted mutants were unable to grow on medium containing oleic acids as the sole carbon source and were nonpathogenic, being defective in both appressorium melanization and host penetration. Carbon 92-98 medium-chain fatty acid-CoA ligase FAA2 Saccharomyces cerevisiae S288C 4-8 11349272-6 2001 An exception occurs when the PAH is generated simultaneously with the aerosol and unusually high solubilities are observed, indicative of adsorption to active carbon surfaces. Carbon 159-165 phenylalanine hydroxylase Homo sapiens 29-32 26219542-4 2015 In this study, multi-walled carbon nanotubes (MWCNTs) were used to effectively deliver HKII(pep) across cellular barriers without compromising their bioactivity. Carbon 28-34 hexokinase 2 Homo sapiens 87-91 11430096-3 2001 Whereas parent Ch 1 is protonated at C-6/C-12, 3 is protonated at C-6 (3aH+) and at C-12 (3bH+) with the latter being the thermodynamic cation. Carbon 15-16 complement C6 Homo sapiens 37-40 11430096-3 2001 Whereas parent Ch 1 is protonated at C-6/C-12, 3 is protonated at C-6 (3aH+) and at C-12 (3bH+) with the latter being the thermodynamic cation. Carbon 15-16 complement C6 Homo sapiens 66-69 26243183-1 2015 A facile and fruitful CVD method is reported for the first time, to synthesize high-quality hexagonal SnS2 nanosheets on carbon cloth via in situ sulfurization of SnO2. Carbon 121-127 sodium voltage-gated channel alpha subunit 11 Homo sapiens 102-106 11154278-4 2001 In addition, splicing of HAC1 transcripts, which has previously been reported to occur during accumulation of unfolded proteins in the endoplasmic reticulum, was observed after the carbon shift. Carbon 181-187 transcription factor HAC1 Saccharomyces cerevisiae S288C 25-29 26716343-1 2015 The aims of this study are immobilization of formaldehyde dehydrogenase (FDH) into nano-space of nanostructured carbon and evaluation as a possible sensor detecting low concentration formaldehyde. Carbon 112-118 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 45-71 11135668-2 2001 Based on a phosphoryl transfer mechanism involving a dissociative transition state, a potent and selective bisubstrate inhibitor for the insulin receptor tyrosine kinase was synthesized by linking ATPgammaS to a peptide substrate analog via a two-carbon spacer. Carbon 247-253 insulin receptor Homo sapiens 137-153 26716343-1 2015 The aims of this study are immobilization of formaldehyde dehydrogenase (FDH) into nano-space of nanostructured carbon and evaluation as a possible sensor detecting low concentration formaldehyde. Carbon 112-118 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 73-76 11257884-10 2001 PAH carbon was incorporated into cell mass and mineralized after complete biodegradation of the PAHs, with 78-102% recoveries of radiolabel for naphthalene and phenanthrene, respectively. Carbon 4-10 phenylalanine hydroxylase Homo sapiens 0-3 11257884-11 2001 PAH carbon incorporation into biomass also varied considerably. Carbon 4-10 phenylalanine hydroxylase Homo sapiens 0-3 26716343-3 2015 Enzyme activity and electrochemical sensing ability of FDH encapsulated into such two carbon materials were compared. Carbon 86-92 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 55-58 11329881-6 2001 Signal peptide of suc2 and alpha chain of human interleukin-2 was fused in frame to suc2 gene, then the two resulting vectors were transformed into EGY48-delta suc, all the transformants can grow in the medium with either raffinose or glucose as carbon source. Carbon 246-252 beta-fructofuranosidase SUC2 Saccharomyces cerevisiae S288C 18-22 26216646-0 2015 Arabidopsis thaliana ggt1 photorespiratory mutants maintain leaf carbon/nitrogen balance by reducing RuBisCO content and plant growth. Carbon 65-71 glutamate:glyoxylate aminotransferase Arabidopsis thaliana 21-25 11073587-4 2000 It was prepared regiospecificaly in two steps from adenine and was amenable to C-8 iodination under basic conditions and to subsequent introduction of the various carbon chains at C-8 by palladium-catalyzed cross-coupling reactions (Stille or Sonogashira). Carbon 163-169 homeobox C8 Homo sapiens 180-183 11069008-0 2000 Ferrocene-Mediated carbon paste electrode modified with D-fructose dehydrogenase for batch mode measurement of D-fructose. Carbon 19-25 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 56-80 11069008-1 2000 A mediated modified carbon paste and renewable surface electrode for fructose amperometric measurement based on D-fructose dehydrogenase (FDH) was prepared and optimized. Carbon 20-26 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 112-136 11069008-1 2000 A mediated modified carbon paste and renewable surface electrode for fructose amperometric measurement based on D-fructose dehydrogenase (FDH) was prepared and optimized. Carbon 20-26 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 138-141 14675814-2 2004 Temperature effect correction parameters have been determined for the aromatic C6/C8 carbons and the deoxyribose C1", C2", and C3" carbons. Carbon 85-92 complement C6 Homo sapiens 79-84 26154277-5 2015 The resulting carbon-supported Pd NPs were characterized by TEM, BET, XRD, and XPS and the Pd loading was calculated by AAS. Carbon 14-20 delta/notch like EGF repeat containing Homo sapiens 65-68 14675814-5 2004 The use of this triplet database for carbon chemical shift predictions shows good accuracy with experimental data, with root-mean-square deviations of 0.09, 0.10, 0.10, and 0.10 ppm and correlation coefficients of 0.999, 0.996, 0.978, and 0.974 for C6/C8, C1", C2", and C3", respectively. Carbon 37-43 complement C6 Homo sapiens 249-254 10998311-1 2000 Commercial activated carbon D43/1 (Carbo-Tech, Essen, Germany) was deashed and modified chemically to increase surface acidity and basicity, as well as to introduce metal cations onto the surface and yet conserve the porosity. Carbon 21-27 leiomodin 1 Homo sapiens 28-33 10954733-3 2000 Brain 2-deoxy-d- [1-(14)C]glucose uptake parallels Igf1 expression in wild-type mice and is profoundly reduced in Igf1-/- mice, particularly in those structures where Igf1 is normally most highly expressed. Carbon 23-25 insulin-like growth factor 1 Mus musculus 51-55 26217961-2 2015 Seven of ArCH2SAr"( -) underwent mesolysis via dissociation of the sigma-bond between the benzylic carbon and sulfur atoms, forming the corresponding radical and anion with the stepwise mechanism or concerted mechanism. Carbon 99-105 zinc finger and BTB domain containing 8 opposite strand Homo sapiens 9-14 10850990-3 2000 Gal4p activates the genes of the galactose utilization pathway permitting the use of galactose as the sole source of carbon and energy. Carbon 117-123 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 0-5 14677929-2 2003 The unique eta2 C=O-metal (iridium) coordination mode leaves the positive charge delocalized within the former aromatic ring. Carbon 16-17 DNA polymerase iota Homo sapiens 11-15 26253003-9 2015 The non-synonymous mutations in HXT2 and CIT1 may function in the presence of mutated MTH1 alleles and could be related to an altered central carbon metabolism in order to ensure production of cytosolic acetyl-CoA in the Pdc negative strain. Carbon 142-148 hexose transporter HXT2 Saccharomyces cerevisiae S288C 32-36 12958217-8 2003 Upon initiation of its import, C-28 StAR dissipates the inner membrane potential and causes swelling of the mitochondria. Carbon 31-32 steroidogenic acute regulatory protein Homo sapiens 36-40 10862874-2 2000 The glycolytic promoters were induced after addition of glucose to ethanol-grown cells, whereas the HXT7 promoter fragment showed a constitutive beta-galactosidase expression on both carbon sources. Carbon 183-189 hexose transporter HXT7 Saccharomyces cerevisiae S288C 100-104 26253003-9 2015 The non-synonymous mutations in HXT2 and CIT1 may function in the presence of mutated MTH1 alleles and could be related to an altered central carbon metabolism in order to ensure production of cytosolic acetyl-CoA in the Pdc negative strain. Carbon 142-148 citrate (Si)-synthase CIT1 Saccharomyces cerevisiae S288C 41-45 25711989-4 2015 Oxidant-rich flames (Phi < 1) were characterized by larger particle size, lower particle number concentration, higher black carbon (BC) concentration, lower brown carbon BrC. Carbon 127-133 glucose-6-phosphate isomerase Homo sapiens 21-24 10805724-4 2000 Deletion of YNG2 results in several phenotypes, including an abnormal multibudded morphology, an inability to utilize nonfermentable carbon sources, heat shock sensitivity, slow growth, temperature sensitivity, and sensitivity to caffeine. Carbon 133-139 histone acetyltransferase YNG2 Saccharomyces cerevisiae S288C 12-16 14534783-3 2003 FDH1 expression can be induced by formate when cells are grown on a medium containing glucose as a carbon source, whereas expression of AOD1 and DAS1 is completely repressed in the presence of glucose. Carbon 99-105 formate dehydrogenase (NAD+) Saccharomyces cerevisiae S288C 0-4 14564684-3 2003 At the single-channel level, the addition of acyl CoAs of differing side-chain length (2 to 16 carbons) to the inside face of membrane patches from ventricular myocytes caused varying increases in pmK(ATP) channel open probability proportional to increases in acyl side-chain length (20 mumol/L acetyl CoA: 310% +/- 90%, 20 mumol/L decanoyl CoA: 570% +/- 150%). Carbon 95-102 phosphomevalonate kinase Homo sapiens 197-200 25711989-4 2015 Oxidant-rich flames (Phi < 1) were characterized by larger particle size, lower particle number concentration, higher black carbon (BC) concentration, lower brown carbon BrC. Carbon 166-172 glucose-6-phosphate isomerase Homo sapiens 21-24 10823703-4 2000 The APCI spectra of alkaloids were predominantly the [M+H]+ ion and major fragment ion, corresponding to the [M+H-H2O]+ ion or the [M+H-CH3COOH]+ ion, and comparison of the spectra showed that the abundance of fragment ions was significantly higher for C-1 beta-form alkaloids than for C-1 alpha-form alkaloids. Carbon 6-7 endogenous retrovirus group K member 1 Homo sapiens 286-295 26110967-1 2015 We describe the stable and isolable dimetalloxycarbene [(TiX3 )2 (mu2 -CO2 -kappa(2) C,O:kappaO")] 5, where X=N-(tert-butyl)-3,5-dimethylanilide, which is stabilized by fluctuating mu2 -kappa(2) C,O:kappa(1) O" coordination of the carbene carbon to both titanium centers of the dinuclear complex 5, as shown by variable-temperature NMR studies. Carbon 239-245 adaptor related protein complex 1 subunit mu 2 Homo sapiens 66-69 10810290-9 2000 In addition, fetal IGF-I infusion increased the conversion of serine to glycine which is likely to have increased the availability of one-carbon groups for biosynthesis. Carbon 138-144 insulin-like growth factor I Ovis aries 19-24 12940866-6 2003 [2-14C]-pyruvate oxidation, which is a measure of the activity of pyruvate carboxylase in introducing pyruvate carbon into the tricarboxylic acid cycle, was increased 1.4-fold in the presence of fatty acid in the UCP3 transgenic mice (3.84 +/- 0.28 vs. 5.36 +/- 0.29 micro mol/h/g). Carbon 111-117 pyruvate carboxylase Mus musculus 66-86 12940866-6 2003 [2-14C]-pyruvate oxidation, which is a measure of the activity of pyruvate carboxylase in introducing pyruvate carbon into the tricarboxylic acid cycle, was increased 1.4-fold in the presence of fatty acid in the UCP3 transgenic mice (3.84 +/- 0.28 vs. 5.36 +/- 0.29 micro mol/h/g). Carbon 111-117 uncoupling protein 3 (mitochondrial, proton carrier) Mus musculus 213-217 26051266-4 2015 In agreement with NBO and AIM analyses, the orbital interaction energy obtained from EDA contributes at least 50% to the total attractive interactions for the carbon-boron bonds indicating their largely covalent nature. Carbon 159-165 ectodysplasin A Homo sapiens 85-88 12892634-2 2003 In contrast, CACT deficiency is conditionally lethal in the fungus Aspergillus nidulans, since loss-of-function mutations in acuH, the translocase structural gene, do not prevent growth on carbon sources other than ketogenic compounds, such as fatty acids. Carbon 189-195 solute carrier family 25 member 20 Homo sapiens 13-17 10844654-0 2000 Expression of yeast INM1 encoding inositol monophosphatase is regulated by inositol, carbon source and growth stage and is decreased by lithium and valproate. Carbon 85-91 inositol monophosphate 1-phosphatase INM1 Saccharomyces cerevisiae S288C 20-24 10806249-5 2000 The enzyme selectively catalyzes the oxidation of CoA esters of fatty acids with 4 to 10 carbon atoms, and exhibits the highest activity on C-6 fatty acids. Carbon 89-95 complement C6 Homo sapiens 140-143 25982115-5 2015 We propose that SCF(Ucc1)-mediated regulation of citrate synthase acts as a metabolic switch for the glyoxylate cycle in response to changes in carbon source, thereby ensuring metabolic versatility and flexibility. Carbon 144-150 citrate synthase Homo sapiens 49-65 10723065-4 2000 Here we provide first evidence that TN-R derived from whole rat brain or cultured oligodendrocytes expresses chondroitin sulfate (CS) glycosaminoglycans (GAGs), i.e., C-4S and C-6S, that are recognized by CS-56, a CS/dermatan sulfate-specific monoclonal antibody. Carbon 130-131 tenascin R Rattus norvegicus 36-40 12829488-7 2003 SP-B(9-36), synthesized with (13)C=O-labeled Ala residues in positions 26, 28, 30, and 32, shifted the beta-sheet marker band to approximately 1600 cm(-1) and thus immediately identified this structural element within the labeled region. Carbon 33-34 surfactant protein B Homo sapiens 0-4 25839973-3 2015 Among these MOF-derived materials, MOF-derived carbonaceous materials are particularly attractive owing to its simple preparation and dual characteristics from carbon and metals. Carbon 47-53 lysine acetyltransferase 8 Homo sapiens 12-15 12754701-4 2003 The cofactor is an unstable reduced pterin with a unique four-carbon side chain, synthesized by a complex pathway that requires the products of at least four different genes (MOCS1, MOCS2, MOCS3, and GEPH). Carbon 62-68 molybdenum cofactor synthesis 1 Homo sapiens 175-180 10757750-1 2000 The Saccharomyces cerevisiae nuclear gene RPM2 encodes a component of the mitochondrial tRNA-processing enzyme RNase P. Cells grown on fermentable carbon sources do not require mitochondrial tRNA processing activity, but still require RPM2, indicating an additional function for the Rpm2 protein. Carbon 147-153 ribonuclease P Saccharomyces cerevisiae S288C 42-46 25839973-3 2015 Among these MOF-derived materials, MOF-derived carbonaceous materials are particularly attractive owing to its simple preparation and dual characteristics from carbon and metals. Carbon 47-53 lysine acetyltransferase 8 Homo sapiens 35-38 10783012-6 2000 The stable carbon isotope (13C/12C) ratio measured by GC-C-IRMS was used to calculate the plasma concentration of [13C]lutein. Carbon 11-17 guanylate cyclase 2C Homo sapiens 54-58 12841945-6 2003 We found that 3,5-dimethoxy-4- hydroxycinnamic acid, the cinnamic acid derivative with two methoxyl groups and hydroxylation at the fourth carbon on the benzene ring, had a higher affinity for the alpha(1A)-adrenoceptor subtype, showing a smaller IC50 value (the concentration for production of 50% inhibition) to displace [(3)H]prazosin binding in rat prostate. Carbon 139-145 adrenoceptor alpha 1A Rattus norvegicus 197-219 25648260-4 2015 Cross-talk was observed between one-carbon and xenobiotic pathways in breast cancer (RFC 80 G>A, COMT H108L and TYMS 5"-UTR 28 bp tandem repeat) and SLE (CYP1A1 m1, MTRR 66 A>G and GSTT1). Carbon 36-42 catechol-O-methyltransferase Homo sapiens 97-101 28060640-8 1999 The reacted carbons in CH3Br are recovered as COx almost quantitatively in air. Carbon 12-19 cytochrome c oxidase subunit 8A Homo sapiens 46-49 25113382-8 2015 Dual incubation of 17,18-EpETE with calphostin C or Y-27632 induced cumulative inhibitory effects on MCh responses in TNF-alpha-incubated tracheal rings. Carbon 47-48 tumor necrosis factor Cavia porcellus 118-127 10628872-1 1999 The yeast transcriptional activator Cat8p has been identified as a factor that is essential for the derepression of genes involved in gluconeogenesis (like FBP1, PCK1, ACR1, ICL1 and MLS1) when only nonfermentable carbon sources are provided. Carbon 214-220 isocitrate lyase 1 Saccharomyces cerevisiae S288C 174-178 12606555-3 2003 The ach1 mutant causes a growth defect in acetate but not in other non-fermentable carbon sources, suggesting that Ach1p is not involved in mitochondrial biogenesis. Carbon 83-89 acetyl-CoA hydrolase Saccharomyces cerevisiae S288C 4-8 26091108-0 2015 An Allergic Lung Microenvironment Suppresses Carbon Nanotube-Induced Inflammasome Activation via STAT6-Dependent Inhibition of Caspase-1. Carbon 45-51 signal transducer and activator of transcription 6 Mus musculus 97-102 12746595-4 2003 This new pouch also incorporates a unique Dual-Carb filter which combines modified and unmodified carbon to help fight the various odour types that an ileostomy can produce. Carbon 98-104 syntaxin 8 Homo sapiens 47-51 12743392-0 2003 Polymeric tris(mu2)-acetone-kappa2O:O)sodium polyiodide at 120 K. In the title compound, [Na(C(3)H(6)O)(3)](n)(I(2))(n), all non-H atoms are in special positions of the space group P6(3)/mcm, with the Na atom in 2b, the I atom in 4c, the carbonyl O atom and the C atom attached to it both in 6g, and the methyl C atom in 12k. Carbon 93-94 adaptor related protein complex 1 subunit mu 2 Homo sapiens 15-18 10489308-1 1999 The effect of anodic surface treatment of activated carbon on adsorption and ion exchange characteristics was investigated in the condition of 35 wt% NaOH electrolyte for 60 s. The acid and base values were determined by a titration technique, and surface and pore structures were studied in terms of BET volumetric measurement with N(2) adsorption. Carbon 52-58 delta/notch like EGF repeat containing Homo sapiens 301-304 10487929-3 1999 This carbon source regulation requires Snf1p and possibly Ssn6p. Carbon 5-11 transcription regulator CYC8 Saccharomyces cerevisiae S288C 58-63 26091108-0 2015 An Allergic Lung Microenvironment Suppresses Carbon Nanotube-Induced Inflammasome Activation via STAT6-Dependent Inhibition of Caspase-1. Carbon 45-51 caspase 1 Mus musculus 127-136 25955439-0 2015 MOF-derived ultrafine MnO nanocrystals embedded in a porous carbon matrix as high-performance anodes for lithium-ion batteries. Carbon 60-66 lysine acetyltransferase 8 Homo sapiens 0-3 10483532-1 1999 We present a set of programs, DREAM+2 (Docking and Reaction programs using Efficient seArch Methods written in C++), for docking computationally generated ligands into macromolecular binding sites. Carbon 111-114 potassium voltage-gated channel interacting protein 3 Homo sapiens 30-35 12817638-1 2003 The carbonaceous component in the Milan urban particulate matter, i.e. the two components black carbon (BC) and organic carbon (OC), has been measured by means of a thermogravimetric analyzer combined with an infrared spectrophotometer (TGA/FT-IR). Carbon 4-10 T-box transcription factor 1 Homo sapiens 237-240 25970036-3 2015 In this study, we develop a simple solid-state reaction method, in which the carbon-coated SnS2 (SnS2/C) anode materials were synthesized by annealing metallic Sn, sulfur powder, and polyacrylonitrile in a sealed vacuum glass tube. Carbon 77-83 sodium voltage-gated channel alpha subunit 11 Homo sapiens 91-95 12817638-5 2003 The total carbon (TC) determinations performed by TGA/FT-IR on Milan urban particulate matter are in good agreement with the results obtained by a total organic carbon (TOC) analyzer operating directly on the solid sample. Carbon 10-16 T-box transcription factor 1 Homo sapiens 50-53 12590462-3 2003 Addition of glycerol reduced the carbon peak intensities of fresh and aged breads, which correlated well with the DSC amylopectin "melting" enthalpy (r(2) = 0.91). Carbon 33-39 desmocollin 3 Homo sapiens 114-117 10462487-9 1999 Functional significance of the spectral data was derived from the known structure of influenza neuraminidase, where a tyrosinate ion is involved in the stabilization of the transition-state carbonium ion, and a tryptophan residue is involved in the binding of the acetyl moiety of the substrate. Carbon 190-199 neuraminidase 1 Homo sapiens 95-108 10421807-4 1999 Other alcohols also interfered with [(125)I]-GnRH isoform or agonist binding: inhibition increased with increasing carbon chain length and was dependent on the isomeric position of the hydroxyl group. Carbon 115-121 gonadotropin releasing hormone 1 Homo sapiens 45-49 25970036-3 2015 In this study, we develop a simple solid-state reaction method, in which the carbon-coated SnS2 (SnS2/C) anode materials were synthesized by annealing metallic Sn, sulfur powder, and polyacrylonitrile in a sealed vacuum glass tube. Carbon 77-83 sodium voltage-gated channel alpha subunit 11 Homo sapiens 97-103 25503937-2 2015 Gas chromatography combustion isotope ratio mass spectrometry (GC-C-IRMS) is capable of measuring the carbon isotope ratio of urinary steroids and this allows differentiation between both. Carbon 102-108 guanylate cyclase 2C Homo sapiens 63-67 10503534-7 1999 The level of T. reesei pdi1 mRNA is also regulated by the carbon source, being lowest in glucose-containing media and highest on carbon sources that induce the genes encoding extracellular enzymes. Carbon 58-64 protein disulfide isomerase PDI1 Saccharomyces cerevisiae S288C 23-27 10503534-7 1999 The level of T. reesei pdi1 mRNA is also regulated by the carbon source, being lowest in glucose-containing media and highest on carbon sources that induce the genes encoding extracellular enzymes. Carbon 129-135 protein disulfide isomerase PDI1 Saccharomyces cerevisiae S288C 23-27 12520537-5 2003 Central to the degradation and turnover of 1,25D is the regulatory multi-catalytic cytochrome P450C24 (CYP24) enzyme that directs the introduction of C-24R groups onto targeted 25-hydroxy substrates. Carbon 0-1 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 83-101 12520537-5 2003 Central to the degradation and turnover of 1,25D is the regulatory multi-catalytic cytochrome P450C24 (CYP24) enzyme that directs the introduction of C-24R groups onto targeted 25-hydroxy substrates. Carbon 0-1 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 103-108 26016674-6 2015 Loss of aromatic carbon was limited by eliminating phenylpyruvate decarboxylase Aro10. Carbon 17-23 phenylpyruvate decarboxylase ARO10 Saccharomyces cerevisiae S288C 80-85 10387080-1 1999 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to form glycine and single carbon groups that are essential for many biosynthetic pathways. Carbon 110-116 serine hydroxymethyltransferase, cytosolic Oryctolagus cuniculus 0-31 10387080-1 1999 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to form glycine and single carbon groups that are essential for many biosynthetic pathways. Carbon 110-116 serine hydroxymethyltransferase, cytosolic Oryctolagus cuniculus 33-37 10387080-2 1999 SHMT requires both pyridoxal phosphate (PLP) and tetrahydropteroylpolyglutamate (H4PteGlun) as cofactors, the latter as a carrier of the single carbon group. Carbon 144-150 serine hydroxymethyltransferase, cytosolic Oryctolagus cuniculus 0-4 12464252-2 2003 Both enzymes hydroxylate progesterone at carbon atoms that lie only 2.6A apart, but CYP17 also metabolizes other steroids and demonstrates additional catalytic activities. Carbon 41-47 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 84-89 25326542-7 2015 Interquartile increases in black carbon (BC), fine particulate matter (PM10 and PMcoarse), UFP, and nitric oxides (NOx) were associated with statistically significantly higher SBP post-exposure (1.2, 1.0, 1.1, and 1.1 mm/Hg, respectively). Carbon 33-39 selenium binding protein 1 Homo sapiens 176-179 12899518-1 2003 Calcitriol (1alpha,25(OH)2D3), the hormonally active form of vitamin D3 (D3) is produced by a cascade of reactions, including photochemical D3 synthesis in the skin and subsequent hydroxylation at the C-25 atom in the liver and finally at C-1alpha position in the kidney. Carbon 0-1 endogenous retrovirus group K member 1 Homo sapiens 239-247 11674467-6 1999 The two-carbon L-arginine homologue (9), prepared from L-phenylalanine, demonstrated the greatest isoform selective inhibition of the compounds examined (IC(50)(iNOS) = 19 and IC(50)(nNOS) = 147 &mgr;M, IC(50)(nNOS)/IC(50)i(NOS) = 7.7). Carbon 8-14 nitric oxide synthase 1 Homo sapiens 183-187 11674467-6 1999 The two-carbon L-arginine homologue (9), prepared from L-phenylalanine, demonstrated the greatest isoform selective inhibition of the compounds examined (IC(50)(iNOS) = 19 and IC(50)(nNOS) = 147 &mgr;M, IC(50)(nNOS)/IC(50)i(NOS) = 7.7). Carbon 8-14 nitric oxide synthase 1 Homo sapiens 214-218 11674490-6 1999 Interestingly, the complex stability constants (log K(S)), or the Gibbs free energy change (-DeltaG degrees ), increase linearly with increasing number of carbon atoms in the guest molecule (N(C)), irrespective of the topological differences of acyclic, cyclic, and bicyclic guests. Carbon 155-161 dunce Drosophila melanogaster 191-195 24983895-0 2015 Extracellular HMGB1 regulates multi-walled carbon nanotube-induced inflammation in vivo. Carbon 43-49 high mobility group box 1 Mus musculus 14-19 10322015-4 1999 Ssb and the ribosomal protein rpL5 mRNAs were up-regulated upon carbon upshift and down-regulated upon amino acid limitation, unlike the mRNA of another cytosolic Hsp70, Ssa. Carbon 64-70 ribosomal 60S subunit protein L5 Saccharomyces cerevisiae S288C 30-34 12537375-0 2002 Renewable-surface sol-gel derived carbon ceramic electrode fabricated by [Ru(bpy)(tpy)Cl]PF6 and its application as an amperometric sensor for sulfide and sulfur oxoanions. Carbon 34-40 sperm associated antigen 17 Homo sapiens 89-92 12537375-2 2002 It consists of a chemically modified carbon ceramic composite electrode (CCE) containing [Ru(bpy)(tpy)Cl]PF6 complex that was constructed by the sol-gel technique. Carbon 37-43 sperm associated antigen 17 Homo sapiens 105-108 24983895-4 2015 In this study, the ability of multi-walled carbon nanotubes (MWCNT) to cause release of HMGB1 in vitro and in vivo, as well as the potential of HMGB1 to function as signal 1 in vitro and in vivo, was determined. Carbon 43-49 high mobility group box 1 Mus musculus 88-93 25775150-0 2015 Carbon nanotube-assisted optical activation of TGF-beta signalling by near-infrared light. Carbon 0-6 transforming growth factor, beta 1 Mus musculus 47-55 12404631-4 2002 For the HH16 substrate, a change of base pair 10.2-11.2 to C-G in stem II further improved activity by about 2.5-fold to 0.8 min(-1) (at 1 mM Mg(2+) concentration, 25 degrees C, pH 7.5). Carbon 59-60 semaphorin 3A Homo sapiens 8-12 10198260-1 1999 Very-long-chain acyl-CoA synthetases (VLCS) activate very-long-chain fatty acids (VLCFA) containing 22 or more carbons to their CoA derivatives. Carbon 111-118 solute carrier family 27 member 2 Homo sapiens 0-36 10198260-1 1999 Very-long-chain acyl-CoA synthetases (VLCS) activate very-long-chain fatty acids (VLCFA) containing 22 or more carbons to their CoA derivatives. Carbon 111-118 solute carrier family 27 member 2 Homo sapiens 38-42 25775150-3 2015 Here, we report a single-walled carbon nanotube (SWCNT)-assisted approach that enables near-infrared light-triggered activation of transforming growth factor beta (TGF-beta) signal transduction, an important signalling pathway in embryonic development and cancer progression. Carbon 32-38 transforming growth factor, beta 1 Mus musculus 164-172 10331270-2 1999 Genes gap1 and gap2 are closely related at the sequence level to the nuclear genes encoding cytosolic and chloroplast GAPDH of higher plants and have recently been shown to play distinct key roles in catabolic and anabolic carbon flow, respectively, of the unicellular cyanobacterium Synechocystis sp. Carbon 223-229 gap1 Gloeobacter violaceus PCC 7421 6-10 12271625-0 2002 Unusual properties of the first copper complex containing a pi(eta 2)-coordinated phosphorus-carbon double bond moiety. Carbon 93-99 DNA polymerase iota Homo sapiens 63-68 12202196-0 2002 Transient amidolytic activity changes of plasmin adsorbed onto carbons. Carbon 63-70 plasminogen Homo sapiens 41-48 25744719-0 2015 MDSC and TGFbeta Are Required for Facilitation of Tumor Growth in the Lungs of Mice Exposed to Carbon Nanotubes. Carbon 95-101 transforming growth factor, beta 1 Mus musculus 9-16 9920883-1 1999 Growth of Saccharomyces cerevisiae with a fatty acid as carbon source was shown previously to require function of either glucose-6-phosphate dehydrogenase (ZWF1) or cytosolic NADP+-specific isocitrate dehydrogenase (IDP2), suggesting dependence of beta-oxidation on a cytosolic source of NADPH. Carbon 56-62 isocitrate dehydrogenase (NADP(+)) IDP2 Saccharomyces cerevisiae S288C 216-220 25744719-4 2015 Here, we report that an acute exposure to single-walled carbon nanotubes (SWCNT) induces recruitment and accumulation of lung-associated myeloid-derived suppressor cells (MDSC) and MDSC-derived production of TGFbeta, resulting in upregulated tumor burden in the lung. Carbon 56-62 transforming growth factor, beta 1 Mus musculus 208-215 12202196-1 2002 The amidolytic activity of plasmin (Pln) that spontaneously adsorbs from solutions to modified-graphite (GR) and glassy carbon (GL) surfaces was studied in the 10-45 degrees C temperature range in the presence of a chromogenic substrate. Carbon 120-126 plasminogen Homo sapiens 27-34 12202196-1 2002 The amidolytic activity of plasmin (Pln) that spontaneously adsorbs from solutions to modified-graphite (GR) and glassy carbon (GL) surfaces was studied in the 10-45 degrees C temperature range in the presence of a chromogenic substrate. Carbon 120-126 plasminogen Homo sapiens 36-39 10092853-4 1999 From these data we calculated the individual flux control coefficients for CPT I over ketogenesis, CO2 production and total carbon flux (0.51 +/- 0.03; -1.30 +/- 0.26; 0.55 +/- 0.07, respectively) and compared them with equivalent coefficients calculated by similar analyses [Drynan, L., Quant, P.A. Carbon 124-130 carnitine palmitoyltransferase 1B Rattus norvegicus 75-80 12202196-1 2002 The amidolytic activity of plasmin (Pln) that spontaneously adsorbs from solutions to modified-graphite (GR) and glassy carbon (GL) surfaces was studied in the 10-45 degrees C temperature range in the presence of a chromogenic substrate. Carbon 128-130 plasminogen Homo sapiens 27-34 10092853-10 1999 In the suckling systems the flux control coefficients for CPT I over ketogenesis specifically and over total carbon flux (< 0.6) are not consistent with the enzyme being rate-limiting. Carbon 109-115 carnitine palmitoyltransferase 1B Rattus norvegicus 58-63 25652650-0 2015 Designed synthesis of size-tunable Ag2S nanoclusters via distinguishable C-S bond cleavage reaction of alkyl- and aryl-thiolates. Carbon 73-74 angiotensin II receptor type 1 Homo sapiens 35-39 12202196-1 2002 The amidolytic activity of plasmin (Pln) that spontaneously adsorbs from solutions to modified-graphite (GR) and glassy carbon (GL) surfaces was studied in the 10-45 degrees C temperature range in the presence of a chromogenic substrate. Carbon 128-130 plasminogen Homo sapiens 36-39 25290645-0 2015 Electrochemical aptasensor for mucin 1 based on dual signal amplification of poly(o-phenylenediamine) carrier and functionalized carbon nanotubes tracing tag. Carbon 129-135 mucin 1, cell surface associated Homo sapiens 31-38 11997390-3 2002 Here we describe a pathway involving cytochrome P450-mediated omega-hydroxylation of the tocopherol phytyl side chain followed by stepwise removal of two- or three-carbon moieties, ultimately yielding the 3"-carboxychromanol metabolite that is excreted in urine. Carbon 164-170 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 48-52 9813062-3 1998 Growth phenotype analyses of the mutants indicate that either cytosolic NADP+-specific isocitrate dehydrogenase (Idp2p) or the hexose monophosphate shunt is essential for growth with fatty acids as carbon sources and for sporulation of diploid strains, a condition associated with high levels of fatty acid synthesis. Carbon 198-204 isocitrate dehydrogenase (NADP(+)) IDP2 Saccharomyces cerevisiae S288C 113-118 9813062-9 1998 The mammalian cytosolic isozyme also functionally substitutes for Idp3p allowing growth on petroselinic acid as a carbon source, suggesting partial localization to peroxisomes and provision of NADPH for beta-oxidation of that fatty acid. Carbon 114-120 isocitrate dehydrogenase (NADP(+)) IDP3 Saccharomyces cerevisiae S288C 66-71 9881155-8 1998 Moreover, the levels of ASN2 and ASN1 mRNA are also reciprocally regulated by carbon and nitrogen metabolites. Carbon 78-84 asparagine synthetase 2 Arabidopsis thaliana 24-28 25290645-2 2015 In this work, a novel method for the determination of MUC 1 in serum was developed based on a sandwich-type electrochemical aptasensor, which combined a dual signal amplification strategy of poly(o-phenylenediamine)-Au nanoparticles (PoPD-AuNPs) hybrid film as carrier and AuNPs functionalized silica/multiwalled carbon nanotubes core-shell nanocomposites (AuNPs/SiO2@MWCNTs) as tracing tag. Carbon 313-319 mucin 1, cell surface associated Homo sapiens 54-59 9774432-4 1998 Multinuclear NMR experiments showed that the reaction catalyzed by GTP cyclohydrolase I involves the release of a proton from C-2" of GTP that is exchanged with the bulk solvent. Carbon 126-127 GTP cyclohydrolase 1 Homo sapiens 67-87 9826191-3 1998 A fluorescent analogue of 12 carbons with a pyrene moiety attached at the end, alone or in conjunction with an anthroyloxy analogue, indicated that LTP could bind two fatty acids although with a marked difference in affinity. Carbon 29-36 lipid transfer protein Zea mays 148-151 9726966-5 1998 Deletion of either the ARP9 or ARP7 gene causes typical swi/snf phenotypes, including growth defects on media containing galactose, glycerol, or sucrose as sole carbon sources. Carbon 161-167 Arp7p Saccharomyces cerevisiae S288C 31-35 9689927-12 1998 These results document the amplification at the site of a putative HSR in an L1210 cell variant of the RFC-1 gene regulating expression of the one-carbon, reduced folate transporter. Carbon 147-153 component of Sp100-rs Mus musculus 67-70 9642094-8 1998 The modelled Thr1 side-chain is located above the gamma-turn bulge such that addition of its nucleophilic hydroxyl group to the electrophilic Gly-1 carbonyl carbon atom may proceed by very small motions. Carbon 148-154 homoserine kinase Saccharomyces cerevisiae S288C 13-17 9642094-10 1998 The same structure also supports addition of the Thr1 hydroxyl group to the carbonyl carbon atom of Leu-2 as a model for the first step in substrate hydrolysis by the proteasome. Carbon 76-82 homoserine kinase Saccharomyces cerevisiae S288C 49-53 9572889-5 1998 Since ACPD is itself somewhat flexible, with four distinctive conformations being identified from molecular modeling studies for the trans isomer and five conformations for the cis isomer, we believed that it would be of interest to examine the activity of an ACPD analogue that has been constrained through the introduction of a single carbon atom bridge. Carbon 337-343 homer scaffold protein 2 Homo sapiens 6-10 11477927-6 1998 Fr2-CA4, one of the fractions obtained by active carbon chromatography from Fr2, exhibited the strongest activity in comparison with other fractions. Carbon 49-55 carbonic anhydrase 4 Mus musculus 4-7 9528770-2 1998 The transcription of IME1 is repressed in the presence of glucose, and a low basal level of IME1 RNA is observed in vegetative cultures with acetate as the sole carbon source. Carbon 161-167 transcription factor IME1 Saccharomyces cerevisiae S288C 21-25 9528770-2 1998 The transcription of IME1 is repressed in the presence of glucose, and a low basal level of IME1 RNA is observed in vegetative cultures with acetate as the sole carbon source. Carbon 161-167 transcription factor IME1 Saccharomyces cerevisiae S288C 92-96 9528770-6 1998 UCS2 promotes the transcription of IME1 in the presence of a nonfermentable carbon source. Carbon 76-82 transcription factor IME1 Saccharomyces cerevisiae S288C 35-39 9495009-2 1998 We report herein that the C-terminal domain, when expressed independently of the integral membrane domain, leads to glucose-independent expression of HXT2 on gluconeogenic carbon sources. Carbon 172-178 hexose transporter HXT2 Saccharomyces cerevisiae S288C 150-154 9438132-1 1997 Cellular titin (c-titin) colocalizes with myosin II in cytoskeletal structures containing actin in vivo and organizes highly ordered myosin bipolar filament arrays in the absence of actin in vitro. Carbon 16-17 titin Homo sapiens 9-14 9438132-1 1997 Cellular titin (c-titin) colocalizes with myosin II in cytoskeletal structures containing actin in vivo and organizes highly ordered myosin bipolar filament arrays in the absence of actin in vitro. Carbon 16-17 titin Homo sapiens 18-23 9398172-5 1997 S. hyicus lipase preferably reacts with medium to long chain carbamates with an optimum for eight carbon atoms. Carbon 98-104 lipase Staphylococcus aureus 10-16 9527373-7 1997 A significant correlation was observed between beta Lact activity of the 215 TEM-1 strains and their MIC at A/S (r = 0.53; p < 0.001), A/C (r = 0.46; p < 0.001), T/TC (r = 0.58; p < 0.001), and P/T (r = 0.42; p < 0.001). Carbon 103-104 hypothetical protein Escherichia coli 77-82 9397406-3 1997 A fluorescent cis-parinaric acid displacement assay was used to show that SCP-2 optimally interacted with 14-22 carbon chain lipidic molecules: polyunsaturated fatty acids > monounsaturated, saturated > branched-chain isoprenoids > branched-chain phytol-derived fatty acids. Carbon 112-118 sterol carrier protein 2 Homo sapiens 74-79 12223814-0 1997 The Differential Expression of Sucrose Synthase in Relation to Diverse Patterns of Carbon Partitioning in Developing Cotton Seed. Carbon 83-89 sucrose synthase Gossypium hirsutum 31-47 9337863-5 1997 In support of this, we find: (i) CNO- inhibits both peroxidative and halogenating activities of MPO and also inhibits the enzyme within intact human neutrophils; (ii) the inhibition is H2O2-dependent, irreversible, accompanied by covalent addition of [14C]CNO- (or a carbon-containing fragment thereof) to the enzyme; (iii) CNO- also inhibits Cl-/H2O2/MPO-mediated bacterial killing. Carbon 267-273 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 33-36 9244277-2 1997 Because choline and glycine betaine may serve as carbon and energy sources in addition to conferring osmoprotection to P. aeruginosa, it seemed possible that induction of plcH is subject to catabolite repression control (CRC) by tricarboxylic cycle intermediates such as succinate. Carbon 49-55 hemolytic phospholipase C Pseudomonas aeruginosa PAO1 171-175 9323366-5 1997 Both sites contain sequences that resemble the previously characterized carbon source-responsive element (CSRE) found in the promoter of the isocitrate lyase gene ICL1. Carbon 72-78 isocitrate lyase 1 Saccharomyces cerevisiae S288C 163-167 9323366-15 1997 In summary, ICL1 and MLS1 share common cis-acting elements, although a distinct mechanism of carbon source control also contributes to MLS1 regulation. Carbon 93-99 isocitrate lyase 1 Saccharomyces cerevisiae S288C 12-16 9226256-4 1997 Expression of FDH1 was found to be induced by choline or methylamine (used as a nitrogen source), as well as by methanol (used as a carbon source). Carbon 132-138 formate dehydrogenase (NAD+) Saccharomyces cerevisiae S288C 14-18 9241209-5 1997 This behavior is explained by the finite aqueous solubility of adventitious carbon that spontaneously deposits on mica after cleavage in air. Carbon 76-82 MHC class I polypeptide-related sequence A Homo sapiens 114-118 9199331-2 1997 Recessive mutations at four unlinked loci, named PAL1 to PAL4, were isolated which prevent alkaline proteinase derepression under conditions of carbon and nitrogen limitation at pH 6.8. Carbon 144-150 Pal1p Saccharomyces cerevisiae S288C 49-53 9212054-5 1997 Somatostatin plus GMPPNP stimulated PTPase activity in vitro when sstr2 was coexpressed with wild type PTP1B or a Cys to Ser (C/S), catalytically inactive PTP1B or with wild type SH2-domain containing PTPase SHP-2. Carbon 114-115 somatostatin receptor 2 Mus musculus 66-71 9083051-9 1997 The high level of FDDCAs that were found suggests that their synthesis is the major metabolic fate for carbon diverted from cholesterol synthesis by a squalene synthase inhibitor. Carbon 103-109 farnesyl diphosphate farnesyl transferase 1 Rattus norvegicus 151-168 9038136-0 1997 Carbon isotope effects on the fructose-1,6-bisphosphate aldolase reaction, origin for non-statistical 13C distributions in carbohydrates. Carbon 0-6 fructose-bisphosphate aldolase B Oryctolagus cuniculus 30-64 9154276-5 1997 Based on the structure-activity relationship investigations, inversion of the configuration, at carbon-9 (C#3) or carbon-11 (C#4), changes the potency and the receptor profile of PGF2 alpha. Carbon 96-102 complement C3 alpha chain Oryctolagus cuniculus 106-109 8970157-1 1996 We show that cells deleted for SNF3, HXT1, HXT2, HXT3, HXT4, HXT6, and HXT7 do not take up glucose and cannot grow on media containing glucose as a sole carbon source. Carbon 153-159 hexose transporter HXT4 Saccharomyces cerevisiae S288C 55-59 8912677-2 1996 By applying top-down control analysis, we quantified the control exerted by CPT I over total carbon flux from palmitoyl-CoA to ketone bodies and carbon dioxide. Carbon 93-99 carnitine palmitoyltransferase 1B Rattus norvegicus 76-81 8912677-4 1996 However, under the sets of conditions we studied, less control is exerted by CPT I over total carbon flux in mitochondria isolated from suckling rats than in those isolated from adult rats. Carbon 94-100 carnitine palmitoyltransferase 1B Rattus norvegicus 77-82 8702284-5 1996 A gram-negative soil bacterium, strain Lep1, was isolated from the consortium and shown to utilize 4-methylquinoline as a source of carbon and energy during growth in liquid medium. Carbon 132-138 late cornified envelope 1A Homo sapiens 39-43 8663351-4 1996 MRS5 codes for an essential protein, as the disruption of this gene is lethal even during growth on fermentable carbon sources. Carbon 112-118 Tim12p Saccharomyces cerevisiae S288C 0-4 21619290-3 1996 The percolating carbon dispersion provides electrical conductivity, oxidoreductase enzymes (e.g., glucose oxidase, lactate oxidase, or l-amino acid oxidase) are used for biocatalysis, metallic palladium is used for electrocatalysis of the biochemical reaction product, and the porous organically modified silica provides a rigid skeleton. Carbon 16-22 interleukin 4 induced 1 Homo sapiens 135-155 12114572-7 2002 Under nitrogen or carbon-starvation conditions, chlorosis was observed earlier in atapg9-1 cotyledons and rosette leaves compared with wild-type plants. Carbon 18-24 autophagy 9 (APG9) Arabidopsis thaliana 82-88 12702297-10 2002 Our results suggest an involvement of Pkc1p in the control of carbon metabolism which is not shared by the downstream MAP kinase cascade. Carbon 62-68 protein kinase C Saccharomyces cerevisiae S288C 38-43 11925208-6 2002 Substituents at the carbons adjacent to the allylic carbinol carbon (i.e., C-2 or C-6 in cyclohexenone-derived substrates) directed the stereochemical course of the rearrangement. Carbon 20-27 complement C6 Homo sapiens 82-85 11925208-6 2002 Substituents at the carbons adjacent to the allylic carbinol carbon (i.e., C-2 or C-6 in cyclohexenone-derived substrates) directed the stereochemical course of the rearrangement. Carbon 20-26 complement C6 Homo sapiens 82-85 12003316-1 2002 The present paper deals with a laboratory-scale study of anaerobic treatment of two commercial mixtures (LS2, LT7) of alcohol ethoxylates with 8-14 carbon atoms and 2 and 7 ethoxy groups. Carbon 148-154 serpin family D member 1 Homo sapiens 105-108 11893779-5 2002 However, when functional LCAT was removed from LDLr(-/-) mice, the CEFA ratio (saturated + monounsaturated/polyunsaturated) of plasma LDL increased 7-fold because of a 2-fold increase in saturated and monounsaturated CE, a 40% reduction in cholesteryl linoleate, and a complete absence of long chain (>18 carbon) polyunsaturated CE (20:4, 20:5n-3, and 22:6n-3), from 29.3% to 0%. Carbon 308-314 lecithin cholesterol acyltransferase Mus musculus 25-29 11827753-4 2002 mTPx I expression was also induced by peroxides in a time- and dose-dependent manner and varied with the carbon source present in the media. Carbon 105-111 peroxiredoxin 2 Mus musculus 0-4 11827753-8 2002 In conclusion, mTPx I expression is under a complex regulatory network, which involves, at least, two signaling pathways: one sensing the carbon source (which is signalized by cAMP) and the other sensing the intracellular redox state (which is signalized by heme). Carbon 138-144 peroxiredoxin 2 Mus musculus 15-19 12188534-4 2002 The maximum plateau achieved in the methane production curve was 1145+/-307 mlCH4(STP)/gVS, obtained for the suspended sludge taken on day 162, when oleate was fed as the sole carbon source at 6 g COD/I. Carbon 176-182 sulfotransferase family 1A member 1 Homo sapiens 82-85 11681966-2 2001 For the NPM case it was found that the CD(2)CH(2)SiMe(3) group, initially bound to oxygen, became the CH(2)CD(2)SiMe(3) group bound to carbon in the end product. Carbon 135-141 nucleophosmin 1 Homo sapiens 8-11 11763057-0 2001 An assay for the enzyme N-acetyl-beta-D-glucosaminidase (NAGase) based on electrochemical detection using screen-printed carbon electrodes (SPCEs). Carbon 121-127 O-GlcNAcase Homo sapiens 24-55 11763057-0 2001 An assay for the enzyme N-acetyl-beta-D-glucosaminidase (NAGase) based on electrochemical detection using screen-printed carbon electrodes (SPCEs). Carbon 121-127 O-GlcNAcase Homo sapiens 57-63 11763057-1 2001 An electrochemical assay for the enzyme N-acetyl-beta-D-glucosaminidase (NAGase) is described, using bare screen-printed carbon electrodes (SPCEs). Carbon 121-127 O-GlcNAcase Homo sapiens 40-71 11763057-1 2001 An electrochemical assay for the enzyme N-acetyl-beta-D-glucosaminidase (NAGase) is described, using bare screen-printed carbon electrodes (SPCEs). Carbon 121-127 O-GlcNAcase Homo sapiens 73-79 11763087-1 2001 A very sensitive and selective procedure was developed for trace measurement of zirconium based on the cathodic adsorptive stripping voltammetry of the zirconium-alizarin red S(ARS) complex at a carbon paste electrode (CPE). Carbon 195-201 RIEG2 Homo sapiens 177-180 11553586-6 2001 Pretreatment of the target tissues with proteinase K decreased gonococcal binding dramatically, whereas pretreatment with neuraminidase and meta-periodate, which cleave carbon-carbon linkages between vicinal hydroxyl groups in carbohydrates, did not affect gonococcal binding. Carbon 169-175 neuraminidase 1 Homo sapiens 122-135 11553586-6 2001 Pretreatment of the target tissues with proteinase K decreased gonococcal binding dramatically, whereas pretreatment with neuraminidase and meta-periodate, which cleave carbon-carbon linkages between vicinal hydroxyl groups in carbohydrates, did not affect gonococcal binding. Carbon 176-182 neuraminidase 1 Homo sapiens 122-135 11566870-5 2001 Ant1p was essential for growth on medium-chain fatty acids as the sole carbon source. Carbon 71-77 Ant1p Saccharomyces cerevisiae S288C 0-5 11493051-8 2001 On the basis of this comparison, we provide evidence that C-N bond formation at the C-6 position, leading to N-aryl 2"-deoxyadenosine analogues, is more sensitive to the ligand used, whereas C-C bond-forming reactions at the same position are not. Carbon 58-59 complement C6 Homo sapiens 84-87 11472905-3 2001 We show that a plasmid (pGM115)-borne transcriptional fusion between the sigma(S)-dependent Escherichia coli promoter P(fic) and lacZ functions as a reliable reporter for carbon availability in Pseudomonas fluorescens. Carbon 171-177 Fic Escherichia coli 109-124 11549036-1 2001 Two new yeast strains (SPT1 and SPT2) were isolated and immobilized on glassy carbon electrodes to form microbial biosensors for estimation of biochemical oxygen demand (BOD). Carbon 78-84 Spt2p Saccharomyces cerevisiae S288C 32-36 11427002-5 2001 It was found that the surface characteristics, including specific surface area, total pore volume, net heat of adsorption, and BET"s C, slightly decrease in anodic surface treatments on activated carbons. Carbon 196-203 delta/notch like EGF repeat containing Homo sapiens 127-130 11419758-9 2001 The activated carbon with the highest BET surface area was produced with the activation of 5 M ZnCl2 solution and, thereafter, pyrolysis at a heating temperature of 500 degrees C for 2 h with a heating rate of 10 degrees C/min. Carbon 14-20 delta/notch like EGF repeat containing Homo sapiens 38-41 11419759-7 2001 The results indicate that in comparison with the DS, the US had a higher carbon content and lower ash content, and accordingly yielded a better activated carbon with a higher BET surface area, pore volume, carbon content and phenol adsorption capacity. Carbon 154-160 delta/notch like EGF repeat containing Homo sapiens 175-178 11419759-7 2001 The results indicate that in comparison with the DS, the US had a higher carbon content and lower ash content, and accordingly yielded a better activated carbon with a higher BET surface area, pore volume, carbon content and phenol adsorption capacity. Carbon 154-160 delta/notch like EGF repeat containing Homo sapiens 175-178 11353491-0 2001 Preparation and Properties of Polymer-Wrapped Single-Walled Carbon Nanotubes We would like to acknowledge the following agencies and foundations for supporting various aspects of this work: the polymer synthesis and spectroscopic characterization of the nanotube-polymer complex was funded by ONR; the chemical preparation and AFM analysis of these materials was supported by the NSF; device fabrication and charge-transport measurements were funded by DARPA and ONR; and the nonlinear microscopy experiments were supported by DARPA and the Keck Foundation. Carbon 60-66 N-ethylmaleimide sensitive factor, vesicle fusing ATPase Homo sapiens 380-383 11254338-0 2001 Thermally Induced Transient Activity Changes of Plasmin Adsorbed onto Bare and Fibrinogen-Modified Graphite and Glassy Carbon Surfaces. Carbon 119-125 plasminogen Homo sapiens 48-55 11254338-1 2001 The occurrence of a thermally induced first-order transition affecting the amidolytic activity of plasmin adsorbed onto bare and protein-modified graphite and glassy carbon was demonstrated in the 10-45 degrees C temperature range in the presence of a chromogenic substrate. Carbon 166-172 plasminogen Homo sapiens 98-105 11179755-3 2001 The C-23 and C-26 oxidation pathways, the minor side chain modification pathways are initiated by hydroxylations at C-23 and C-26 of the side chain and lead to the formation of the end product, calcitriol lactone. Carbon 4-5 nucleolin Homo sapiens 116-120 11179755-8 2001 To prevent C-23 and C-24 hydroxylations, cis or trans double bonds, or a triple bond are incorporated in between C-23 and C-24. Carbon 11-12 nucleolin Homo sapiens 113-117 11179755-8 2001 To prevent C-23 and C-24 hydroxylations, cis or trans double bonds, or a triple bond are incorporated in between C-23 and C-24. Carbon 20-21 nucleolin Homo sapiens 113-117 11290207-1 2001 Field-induced commensurate transverse magnetic ordering is observed in the Haldane-gap compound Ni(C(5)D(14)N(2))2N(3)(PF(6)) by means of neutron diffraction. Carbon 99-100 sperm associated antigen 17 Homo sapiens 119-124 11169757-3 2001 We demonstrate the importance of transcriptional activators Hap4, Cat8 and Pip2 for the carbon source-dependent regulation of MDH1, MDH2 and MDH3, respectively. Carbon 88-94 malate dehydrogenase MDH1 Saccharomyces cerevisiae S288C 126-130 11701096-7 2001 CONCLUSIONS: The best Fhit inhibitors obtained to date separate two or more 5"-O-phosphoromonothioadenosyl moieties with as many bond lengths as in AppppA, maintain oxygen at the location of the alpha-beta bridging oxygen, and replace carbon for the beta phosphorus. Carbon 235-241 fragile histidine triad diadenosine triphosphatase Homo sapiens 22-26 11159754-8 2001 The catalytic activity of this new CYP2B is not yet known, but as previous authors have reported that other members of this sub-family (CYP2B1 or 2B2) metabolize the selective oesophageal carcinogen N:-nitrosomethylbutylamine with the chemical selectivity necessary for carcinogenesis, i.e. they preferentially hydroxylate the alpha-carbon of the butyl chain, this new CYP2B may be the nitrosamine-activating enzyme of the oesophagus. Carbon 333-339 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 136-149 11181711-6 2001 These novel approaches show that the oxidative deamination of glutamate can make a significant contribution to mitochondrial glutamate metabolism and that GDH can support the aminotransferases in funneling carbon from glutamate into the TCA cycle. Carbon 206-212 glutamate dehydrogenase Solanum tuberosum 155-158 11125145-3 2000 A combination of location and expression profiles was used to identify genes whose expression is directly controlled by Gal4 and Ste12 as cells respond to changes in carbon source and mating pheromone, respectively. Carbon 166-172 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 120-124 25562443-7 2015 We also found that the hGOAT active site exhibits a marked preference for binding an eight-carbon acyl chain, which potentially explains the biological observation of ghrelin octanoylation in light of the acyl donor promiscuity reported for GOAT. Carbon 91-97 membrane bound O-acyltransferase domain containing 4 Homo sapiens 23-28 11125145-3 2000 A combination of location and expression profiles was used to identify genes whose expression is directly controlled by Gal4 and Ste12 as cells respond to changes in carbon source and mating pheromone, respectively. Carbon 166-172 homeodomain family transcription factor STE12 Saccharomyces cerevisiae S288C 129-134 25562443-7 2015 We also found that the hGOAT active site exhibits a marked preference for binding an eight-carbon acyl chain, which potentially explains the biological observation of ghrelin octanoylation in light of the acyl donor promiscuity reported for GOAT. Carbon 91-97 appetite-regulating hormone Capra hircus 167-174 11135983-1 2000 We present a new experimental value for the magnetic moment of the electron bound in hydrogenlike carbon (12C5+): g(exp) = 2.001 041 596 (5). Carbon 98-104 muscleblind like splicing regulator 1 Homo sapiens 17-20 25562443-7 2015 We also found that the hGOAT active site exhibits a marked preference for binding an eight-carbon acyl chain, which potentially explains the biological observation of ghrelin octanoylation in light of the acyl donor promiscuity reported for GOAT. Carbon 91-97 membrane bound O-acyltransferase domain containing 4 Homo sapiens 24-28 25543984-0 2015 Adsorption properties of an activated carbon for 18 cytokines and HMGB1 from inflammatory model plasma. Carbon 38-44 high mobility group box 1 Homo sapiens 66-71 11073899-4 2000 Here we show, using DAL80 fused to the carbon-regulated GAL1,10 or copper-regulated CUP1 promoter, that GAT1 expression is inversely regulated by the level of DAL80 expression, i.e., as DAL80 expression increases, GAT1 expression decreases. Carbon 39-45 galactokinase Saccharomyces cerevisiae S288C 56-63 11073899-4 2000 Here we show, using DAL80 fused to the carbon-regulated GAL1,10 or copper-regulated CUP1 promoter, that GAT1 expression is inversely regulated by the level of DAL80 expression, i.e., as DAL80 expression increases, GAT1 expression decreases. Carbon 39-45 Gat1p Saccharomyces cerevisiae S288C 104-108 11073899-4 2000 Here we show, using DAL80 fused to the carbon-regulated GAL1,10 or copper-regulated CUP1 promoter, that GAT1 expression is inversely regulated by the level of DAL80 expression, i.e., as DAL80 expression increases, GAT1 expression decreases. Carbon 39-45 Gat1p Saccharomyces cerevisiae S288C 214-218 25543984-1 2015 The ability of an activated carbon (AC) to adsorb 18 different cytokines with molecular weights ranging from 8 kDa to 70 kDa and high mobility group box-1 (HMGB1) from inflammatory model plasma at 310 K and the mechanisms of adsorption were examined. Carbon 28-34 high mobility group box 1 Homo sapiens 129-154 25543984-1 2015 The ability of an activated carbon (AC) to adsorb 18 different cytokines with molecular weights ranging from 8 kDa to 70 kDa and high mobility group box-1 (HMGB1) from inflammatory model plasma at 310 K and the mechanisms of adsorption were examined. Carbon 28-34 high mobility group box 1 Homo sapiens 156-161 25540822-6 2015 Together, our approaches identified 40 new SBP ligands, generated experiment-based annotations for 2084 SBPs in 71 isofunctional clusters, and defined numerous metabolic pathways, including novel catabolic pathways for the utilization of ethanolamine as sole nitrogen source and the use of d-Ala-d-Ala as sole carbon source. Carbon 310-316 selenium binding protein 1 Homo sapiens 43-46 11132607-9 2000 The protein kinase C inhibitors H-7, calphostin C and K252b, and the tyrosine kinase inhibitor, genistein, significantly inhibited the production of HGF in the coculture. Carbon 19-20 hepatocyte growth factor Homo sapiens 149-152 25051535-5 2015 Moreover, the electrodepositing gold nanoparticles (AuNPs) on the bare glass carbon electrode (GCE) with enhanced surface area could capture a large amount of primary anti-CA15-3 to improve the sensitivity of the immunosensor. Carbon 77-83 mucin 1, cell surface associated Homo sapiens 172-178 11097841-4 2000 We also revealed that the 28-bp region fused with a reporter gene harbored Yhp1-dependent URS (upstream repression sequence) activity and that the transcription of YHP1 was repressed by nonfermentable carbon source. Carbon 201-207 Yhp1p Saccharomyces cerevisiae S288C 164-168 11097841-5 2000 In this study, we found, using a 5"-deletion series of the YHP1 promoter fused with a reporter gene, that the URS responsible for repression of YHP1 transcription with a nonfermentable carbon source is located at a region from nt -696 to -466 of the YHP1 promoter. Carbon 185-191 Yhp1p Saccharomyces cerevisiae S288C 59-63 11097841-5 2000 In this study, we found, using a 5"-deletion series of the YHP1 promoter fused with a reporter gene, that the URS responsible for repression of YHP1 transcription with a nonfermentable carbon source is located at a region from nt -696 to -466 of the YHP1 promoter. Carbon 185-191 Yhp1p Saccharomyces cerevisiae S288C 144-148 11097841-5 2000 In this study, we found, using a 5"-deletion series of the YHP1 promoter fused with a reporter gene, that the URS responsible for repression of YHP1 transcription with a nonfermentable carbon source is located at a region from nt -696 to -466 of the YHP1 promoter. Carbon 185-191 Yhp1p Saccharomyces cerevisiae S288C 144-148 11097841-6 2000 We also identified and delimited a UAS (upstream activation sequence), which confers activation in both fermentable and nonfermentable carbon source media, to be from nt -356 to -306 of the YHP1 promoter. Carbon 135-141 Yhp1p Saccharomyces cerevisiae S288C 190-194 25551418-0 2015 Preparation of conformationally restricted beta(2,2)- and beta(2,2,3)-amino esters and derivatives containing an all-carbon quaternary center. Carbon 117-123 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 43-53 11132644-8 2000 UV RR spectrum gave a prominent band due to cis C=C stretch of phospholipids tightly bound to purified CcO. Carbon 48-49 cytochrome c oxidase subunit 6A1, mitochondrial Bos taurus 103-106 11132644-8 2000 UV RR spectrum gave a prominent band due to cis C=C stretch of phospholipids tightly bound to purified CcO. Carbon 50-51 cytochrome c oxidase subunit 6A1, mitochondrial Bos taurus 103-106 25551418-0 2015 Preparation of conformationally restricted beta(2,2)- and beta(2,2,3)-amino esters and derivatives containing an all-carbon quaternary center. Carbon 117-123 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 58-68 10988074-5 2000 While this conformation allows endoperoxide formation between C-11 and C-9, it also implies that a subsequent conformational rearrangement must occur to allow formation of the C-8/C-12 bond and to position C-15 for attack by a second molecule of oxygen. Carbon 62-63 homeobox C8 Homo sapiens 176-179 25551418-4 2015 The highly challenging preparation of contiguous tertiary and all-carbon quaternary centers was successfully used to generate several beta(2,2,3)-amino esters, such as derivatives of homoproline, homoalanine, and homopipecolinic esters. Carbon 66-72 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 134-144 25874968-0 2015 Carbon nanotube-polyamidoamine dendrimer hybrid-modified electrodes for highly sensitive electrochemical detection of microRNA24. Carbon 0-6 microRNA 24-1 Homo sapiens 118-128 11014594-2 2000 Specifically, the remote correlation between the guanidinium nitrogen 15Nepsilon of arginine 71, which serves as the hydrogen donor, and the acceptor carboxylate carbon 13CO2gamma of aspartate 100 in a 12 kDa protein, human FKBP12, is detected via the trans-hydrogen bond 3h JNepsilonCO2gamma coupling by employing a novel HNCO-type experiment, soft CPD-HNCO. Carbon 162-168 FKBP prolyl isomerase 1A pseudogene 2 Homo sapiens 224-230 25900475-5 2015 The results strongly supported that in wildtype furin but not S386G and C198G mutants, following S386/scissile carbon attack (4.0 A), the peptide retracted from the active site, representing peptide release post hydrolysis. Carbon 111-117 furin, paired basic amino acid cleaving enzyme Homo sapiens 48-53 10869806-5 2000 The presence of a C-->T (Ala-->Val) polymorphism in exon 2 of the Cat D gene has been reported to be associated with an increased risk of AD. Carbon 18-21 cathepsin D Homo sapiens 66-71 25461681-0 2015 Suppression of c-Myc is involved in multi-walled carbon nanotubes" down-regulation of ATP-binding cassette transporters in human colon adenocarcinoma cells. Carbon 49-55 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 86-106 10794706-3 2000 Lengthening the carbon tether resulted in a decrease in NR1/2B potency. Carbon 16-22 glutamate ionotropic receptor NMDA type subunit 1 Rattus norvegicus 56-62 25461681-4 2015 In this study, we found that multiwalled carbon nanotubes (MWCNTs) reduced transport activity and expression of ABC transporters including ABCB1/Pgp and ABCC4/MRP4 in human colon adenocarcinoma Caco-2 cells. Carbon 41-47 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 112-115 25354849-3 2014 The nickel atoms are bonded in an eta(2) coordination mode with Ni-C distances of 2.001(3)-2.037(3) A and a close approach of the fullerenes with a 9.716 A center-to-center distance. Carbon 67-68 endothelin receptor type A Homo sapiens 34-37 10744740-2 2000 First, two atp1 mutations (atp1-1 and atp1-2) were characterized that prevent the growth of yeast on non-fermentable carbon sources. Carbon 117-123 ATP synthase complex assembly protein ATP12 Saccharomyces cerevisiae S288C 38-44 25360456-0 2014 Efficient oxygen reduction by nanocomposites of heterometallic carbide and nitrogen-enriched carbon derived from the cobalt-encapsulated indium-MOF. Carbon 93-99 lysine acetyltransferase 8 Homo sapiens 144-147 10803891-2 2000 Overexpression of the gene (XKS1) for the pentose phosphate pathway (PPP) enzyme xylulokinase (XK) increased the ethanol yield by almost 85% and resulted in ethanol yields [0.61 C-mmol (C-mmol consumed xylulose)(-1)] that were close to the theoretical yield [0.67 C-mmol (C-mmol consumed xylulose)(-1)]. Carbon 178-179 xylulokinase Saccharomyces cerevisiae S288C 28-32 10601259-3 1999 The alpha-carbon of the conserved lysine present near the C-terminal end of the transmembrane helix (Lys(1125) in alpha2, Lys(1022) in alpha5, Lys(752) in beta1, and Lys(724) in beta2) is buried in the plasma membrane, and the charged amino group most likely reaches into the polar head-group region of the lipid bilayer. Carbon 10-16 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 178-183 25525877-3 2014 Here, we show that the nucleocytosolic acetyl-CoA synthetase enzyme, ACSS2, supplies a key source of acetyl-CoA for tumors by capturing acetate as a carbon source. Carbon 149-155 acyl-CoA synthetase short chain family member 2 Homo sapiens 69-74 10556063-7 1999 The Daf-c phenotype was suppressed by daf-7 cDNA expression or a daf-3 null mutation. Carbon 8-9 Dauer larva development regulatory growth factor daf-7 Caenorhabditis elegans 38-43 10497229-8 1999 The data show that the dehydrogenase domains of yeast MFE-2 have different substrate specificities required to allow the yeast to propagate optimally on fatty acids as the carbon source. Carbon 172-178 hydroxysteroid 17-beta dehydrogenase 4 Homo sapiens 54-59 8810042-6 1996 Transcription of KNH1 was found to be carbon-source and kre9 delta dependent, but SKN7 independent, suggesting that KNH1 is subject to alternative transcriptional control. Carbon 38-44 Knh1p Saccharomyces cerevisiae S288C 17-21 8810042-6 1996 Transcription of KNH1 was found to be carbon-source and kre9 delta dependent, but SKN7 independent, suggesting that KNH1 is subject to alternative transcriptional control. Carbon 38-44 Kre9p Saccharomyces cerevisiae S288C 56-60 10500492-2 1999 In this immunosensor, Nafion was used to immobilize an anti-hCG monoclonal antibody onto a glassy carbon electrode. Carbon 98-104 chorionic gonadotropin subunit beta 5 Homo sapiens 60-63 25526194-4 2014 We found that the IRGM rs13361189 polymorphism was significantly associated with an increased risk of CD [C allele vs T allele: odds ratio (OR) = 1.30, 95% confidence interval (CI) = 1.05-1.61, P = 0.017; CC + CT vs TT: OR = 1.32, 95%CI = 1.06-1.64, P = 0.013]. Carbon 102-103 immunity related GTPase M Homo sapiens 18-22 8730097-8 1996 In contrast, CDC25 accumulation is slightly reduced when glucose is replaced by a nonfermentable carbon source. Carbon 97-103 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 13-18 25281760-2 2014 Our previous in vitro studies suggested that ELOVL6 elongated long-chain saturated fatty acids and monounsaturated fatty acids with chain lengths of 12 to 16 carbons. Carbon 158-165 ELOVL family member 6, elongation of long chain fatty acids (yeast) Mus musculus 45-51 8622676-8 1996 Mig1-VP16 can activate transcription from promoters containing Mig1-binding sites and suppresses the inability of Snf1-deficient cells to grow on certain carbon sources. Carbon 154-160 transcription factor MIG1 Saccharomyces cerevisiae S288C 0-4 10441383-9 1999 Recently, it was found that 1alpha,25(OH)(2)D(3)-24-hydroxylase (CYP24) can hydroxylate carbons 23, 24, and 26 of various vitamin D(3) compounds. Carbon 88-95 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 65-70 25278015-7 2014 This study reported the features of a sustainable bioprocess for the production of recombinant bovine chymosin in P. pastoris by fermentation in stirred-tank bioreactors using biodiesel-derived glycerol as a low-cost carbon source. Carbon 217-223 chymosin Bos taurus 102-110 10474184-2 1999 SOD1 expression was necessary to ensure longevity on all carbon sources tested. Carbon 57-63 superoxide dismutase SOD1 Saccharomyces cerevisiae S288C 0-4 25357088-1 2014 We report a fluorescence correlation spectroscopy (FCS) study of the assembly pathway of the AAA+ protein ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) activase (Rca), a ring-forming ATPase responsible for activation of inhibited Rubisco complexes for biological carbon fixation. Carbon 275-281 ribulose bisphosphate carboxylase/oxygenase activase 2, chloroplastic Gossypium hirsutum 106-178 10328823-6 1999 The ACN8, ACN17, and ACN18 genes were isolated by functional complementation of the respective mutant"s inability to utilize acetate as a carbon and energy source, and these genes were shown to encode subunits of metabolic enzymes. Carbon 138-144 fructose 1,6-bisphosphate 1-phosphatase Saccharomyces cerevisiae S288C 4-8 10328823-6 1999 The ACN8, ACN17, and ACN18 genes were isolated by functional complementation of the respective mutant"s inability to utilize acetate as a carbon and energy source, and these genes were shown to encode subunits of metabolic enzymes. Carbon 138-144 succinate dehydrogenase iron-sulfur protein subunit SDH2 Saccharomyces cerevisiae S288C 10-15 10330477-7 1999 All three ammonium transporters showed diurnal variation in expression, but AtAMT1;3 transcript levels peaked with ammonium uptake at the end of the light period, suggesting that AtAMT1;3 provides a link between nitrogen assimilation and carbon provision in roots. Carbon 238-244 anthranilate synthase alpha subunit 1 Arabidopsis thaliana 76-82 10330477-7 1999 All three ammonium transporters showed diurnal variation in expression, but AtAMT1;3 transcript levels peaked with ammonium uptake at the end of the light period, suggesting that AtAMT1;3 provides a link between nitrogen assimilation and carbon provision in roots. Carbon 238-244 anthranilate synthase alpha subunit 1 Arabidopsis thaliana 179-185 8576129-12 1996 This suggests that calmodulin can regulate the functional activity of C-CAM. Carbon 70-71 calmodulin 1 Rattus norvegicus 19-29 8617211-9 1996 Finally, our results indicate that differential stability on different carbon sources also plays a role in determining the steady-state level of the SUC2 mRNA. Carbon 71-77 beta-fructofuranosidase SUC2 Saccharomyces cerevisiae S288C 149-153 32261890-2 2014 8.0 +- 0.5 mum was synthesized using a simple, one-step electrochemical method, and it was highly dispersed on to a reduced graphene oxide (RGO) modified glassy carbon electrode (GCE) support for the first time. Carbon 161-167 glycine cleavage system protein H Homo sapiens 179-182 8808460-4 1996 Similarly, IL-2R plasma levels were significantly higher in HD (378.5 +/- 164.6 U/ml) than in UR (189.5 +/- 89.3 U/ml) and C (11.2 +/- 2.68 U/ml). Carbon 123-124 interleukin 2 receptor subunit alpha Homo sapiens 11-16 8548454-1 1996 Here we investigate the effects of the naturally occurring threonine-linked L-fucose moiety on the structure, dynamics and stability of the proteinase inhibitor PMP-C (Pars intercerebralis major peptide C). Carbon 165-166 endogenous retrovirus group K member 18 Homo sapiens 140-150 25343451-7 2014 In addition, injection of high-dose poly(I: C) to mimic an acute RNA virus infection significantly accelerated diabetes development in young SR-A-/- NOD mice compared with untreated SR-A-/- NOD mice. Carbon 44-45 macrophage scavenger receptor 1 Mus musculus 141-145 8522518-1 1995 Evidence documenting the requirement for a functional DNA polymerase I when Salmonella typhimurium LT2 uses ethanolamine (EA), 1,2-propanediol (1,2-PDL), or propionate (PRP) as the sole carbon and energy source is presented. Carbon 186-192 DNA polymerase I Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 54-70 10378276-1 1999 BACKGROUND: Pyridoxal-5"-phosphate (PLP) dependent enzymes catalyze a broad range of reactions, resulting in bond cleavage at C alpha, C beta, or C gamma carbons of D and L amino acid substrates. Carbon 154-161 pyridoxal phosphatase Homo sapiens 36-39 25337946-10 2014 C-containing genotypes of mir-196a2 act as a risk role for overall survival. Carbon 0-1 microRNA 196a-2 Homo sapiens 26-35 10367950-5 1999 Due to a higher C + G content the numbers of putative CpG immune (Th1) stimulatory motifs were highest in the synthetic gp160 gene. Carbon 16-17 leucyl/cystinyl aminopeptidase Mus musculus 120-125 8542195-4 1995 Formation of the corresponding C-6 phosphorylated 2-FDG analog with hexokinase, followed by treatment of the resulting phosphorylated products with phosphoglucose isomerase, resulted in the observation of additional 19F resonances consistent with the corresponding 2-fluoro-2-deoxy-D-mannose-6-phosphate metabolite. Carbon 31-32 glucose-6-phosphate isomerase Homo sapiens 148-172 24836015-4 2014 The resulted flowerlike AuNPs@C60 nanoparticles were modified onto the glassy carbon electrode to achieve the sensor (AuNPs@C60/GCE). Carbon 78-84 glycine decarboxylase Homo sapiens 128-131 10102376-0 1999 Dbf2 is implicated in a Cbt1-dependent pathway following a shift from glucose to galactose or non-fermentable carbon sources in Saccharomyces cerevisiae. Carbon 110-116 serine/threonine-protein kinase DBF2 Saccharomyces cerevisiae S288C 0-4 10102376-8 1999 Therefore, Dbf2 may be required not only during mitosis but also during growth on non-fermentable carbon sources. Carbon 98-104 serine/threonine-protein kinase DBF2 Saccharomyces cerevisiae S288C 11-15 25244161-4 2014 To create a glucose bioanode, the porous-carbon-modified electrode was further coated with a biocatalytic hydrogel composed of a conductive redox polymer, deglycosylated flavin adenine dinucleotide-dependent glucose dehydrogenase (d-FAD-GDH), and a cross-linker. Carbon 41-47 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 237-240 10229922-0 1999 Complex hprt deletion events are recovered after exposure of human lymphoblastoid cells to high-LET carbon and neon ion beams. Carbon 100-106 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 8-12 10229922-1 1999 Hypoxanthine phosphoribosyltransferase gene (hprt) mutations were induced in human TK-6 lymphoblastoid cells by irradiation at a linear energy transfer (LET) of 250 or 310 keV/micron for carbon and neon ions, respectively. Carbon 187-193 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 45-49 7499355-5 1995 Mutant yeast cells expressing COPT1 exhibit nearly wild type behavior with regard to growth on a nonfermentable carbon source and resistance to copper and iron starvation. Carbon 112-118 copper transporter 1 Arabidopsis thaliana 30-35 7563095-10 1995 Different from most other catalytic triads that catalyse the hydrolysis of an amide or ester bond, the catalytic triad in the active site of PTPS seems to be involved in the deprotonation of the substrate"s side-chain carbons. Carbon 218-225 6-pyruvoyltetrahydropterin synthase Homo sapiens 141-145 10230063-6 1999 Each growing point contained a tip-focused gradient of [Ca2+]c. Experimental generation of a new [Ca2+]c gradient in root hairs pre-treated with microtubule antagonists, using the caged-calcium ionophore Br-A23187, was capable of inducing the formation of a new growth point at the site of elevated calcium influx. Carbon 2-3 TCV-interacting protein Arabidopsis thaliana 31-34 25056875-0 2014 ABC spotlight on carbon nanotubes (CNTs). Carbon 17-23 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-3 10094465-5 1999 Protein binding to carbon source response elements of the ICL1 promoter was competed by all three elements to various extents by the respective ACR1 sequences. Carbon 19-25 isocitrate lyase 1 Saccharomyces cerevisiae S288C 58-62 9920883-6 1999 This proposal is supported by the finding that the sensitivity to exogenous hydrogen peroxide previously reported for DeltaZWF1 mutant strains is less pronounced when analyses are conducted with a nonfermentable carbon source, a condition associated with elevated expression of IDP2. Carbon 212-218 isocitrate dehydrogenase (NADP(+)) IDP2 Saccharomyces cerevisiae S288C 278-282 7592663-1 1995 The berberine bridge enzyme ((S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming), EC 1.5.3.9) catalyzes the oxidative cyclization of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon, C-8, of (S)-scoulerine. Carbon 209-215 homeobox C8 Homo sapiens 217-220 25317069-2 2014 Nicotinamide-N-methyltransferase (NNMT) is one of the key enzymes of one-carbon metabolism. Carbon 73-79 nicotinamide N-methyltransferase Homo sapiens 0-32 7562931-4 1995 These compounds inhibit HNE by forming both a covalent bond between the ketone carbonyl carbon atom and the hydroxyl group of Ser-195 and a hydrogen bond between the benzoxazole nitrogen atom and His-57. Carbon 79-85 elastase, neutrophil expressed Homo sapiens 24-27 7642141-0 1995 Carbon source-dependent regulation of the acetyl-coenzyme A synthetase-encoding gene ACS1 from Saccharomyces cerevisiae. Carbon 0-6 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 85-89 7642141-3 1995 Northern hybridization revealed a strong depression of ACS1 transcripts in a strain grown on the nonfermentable carbon sources, acetate or ethanol. Carbon 112-118 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 55-59 7642141-6 1995 The carbon source-dependent expression was further investigated by the use of an ACS1::lacZ fusion gene, showing complete repression on easily fermentable sugars such as glucose, maltose, sucrose or galactose. Carbon 4-10 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 81-85 7642141-7 1995 Binding sites for the yeast general regulatory factors, Abf1p and Reb1p, together with a sequence reminiscent of the recently identified carbon source-responsive element (CSRE), could be detected in the ACS1 upstream region, presumably mediating the observed regulatory phenotype of this ACS isoenzyme. Carbon 137-143 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 203-207 9826521-1 1998 The Saccharomyces cerevisiae PLC1 gene encodes a homolog of the delta isoform of mammalian phosphoinositide-specific phospholipase C. Cells deleted for PLC1 gene (plc1Delta) are viable but display several phenotypes, including temperature and osmotic sensitivity and defects in utilization of carbon sources other than glucose. Carbon 293-299 phosphatidylinositol phospholipase C Saccharomyces cerevisiae S288C 29-33 9873629-1 1998 Electroenzymatic reduction of NAD+ to NADH for subsequent use in enzymatic synthesis has been carried out at carbon electrodes bearing lipoamide dehydrogenase (LiDH) immobilized under a Nafion film. Carbon 109-115 dihydrolipoamide dehydrogenase Homo sapiens 135-158 25317069-2 2014 Nicotinamide-N-methyltransferase (NNMT) is one of the key enzymes of one-carbon metabolism. Carbon 73-79 nicotinamide N-methyltransferase Homo sapiens 34-38 25096242-2 2014 In this work, we proposed a simple in situ activation approach by dipping CdS NCs film on glass carbon electrode (CdS NCs/GCE) in an activation solution containing H2O2 and citric acid, resulting in a ~58-fold enhancement of ECL intensity in the presence of coreactant H2O2. Carbon 96-102 glycine cleavage system protein H Homo sapiens 122-125 9873629-1 1998 Electroenzymatic reduction of NAD+ to NADH for subsequent use in enzymatic synthesis has been carried out at carbon electrodes bearing lipoamide dehydrogenase (LiDH) immobilized under a Nafion film. Carbon 109-115 dihydrolipoamide dehydrogenase Homo sapiens 160-164 9729766-6 1998 Biochemical and physiological characterization of carbon metabolic mutants, along with the analysis of cloned genes and their corresponding gene products, have greatly advanced our understanding of the function of enzymes such as citrate synthase, oxoglutarate dehydrogenase, pyruvate carboxylase and malic enzymes. Carbon 50-56 citrate synthase Homo sapiens 230-246 9729766-6 1998 Biochemical and physiological characterization of carbon metabolic mutants, along with the analysis of cloned genes and their corresponding gene products, have greatly advanced our understanding of the function of enzymes such as citrate synthase, oxoglutarate dehydrogenase, pyruvate carboxylase and malic enzymes. Carbon 50-56 oxoglutarate dehydrogenase Homo sapiens 248-274 7758459-2 1995 The intracellular level of the carrier protein, as well as the level of the AAC2-gene-specific mRNA, is influenced by the presence or absence of oxygen or of heme, and it is subject to carbon-source control. Carbon 185-191 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 76-80 7715603-2 1995 This result and the fact that growth on non-glucose carbon sources also suppresses rna1-1 led us to propose that RNA processing and export of RNA from the nucleus are responsive to carbon source regulation. Carbon 52-58 Prp11p Saccharomyces cerevisiae S288C 83-89 25161193-8 2014 IMPORTANCE: In Escherichia coli, the response regulator ArcA maintains homeostasis of redox carriers under O2-limiting conditions through a comprehensive repression of carbon oxidation pathways that require aerobic respiration to recycle redox carriers. Carbon 168-174 arginine deiminase Escherichia coli 56-60 7715603-2 1995 This result and the fact that growth on non-glucose carbon sources also suppresses rna1-1 led us to propose that RNA processing and export of RNA from the nucleus are responsive to carbon source regulation. Carbon 181-187 Prp11p Saccharomyces cerevisiae S288C 83-89 9663674-10 1998 In the presence of rapidly metabolizable carbon sources, ATP-dependent phosphorylation of HPr at Ser-46 by HPr kinase inhibits phosphorylation by enzyme I, and PRD-containing regulators cannot, therefore, be stimulated and are inactive. Carbon 41-47 haptoglobin-related protein Homo sapiens 90-93 9663674-10 1998 In the presence of rapidly metabolizable carbon sources, ATP-dependent phosphorylation of HPr at Ser-46 by HPr kinase inhibits phosphorylation by enzyme I, and PRD-containing regulators cannot, therefore, be stimulated and are inactive. Carbon 41-47 haptoglobin-related protein Homo sapiens 107-110 24986452-4 2014 In the tested compounds, electron withdrawing fluoro (5k and 5e), chloro (5j and 5d), and bromo (5l and 5f) substitution at the para position of the phenyl ring attached to C-2 and C-6 carbons of the piperidine moiety outperformed cytotoxic and antimicrobial activities. Carbon 185-192 complement C6 Homo sapiens 181-184 7586025-0 1995 Expression of the FOX1 gene of Saccharomyces cerevisiae is regulated by carbon source, but not by the known glucose repression genes. Carbon 72-78 acyl-CoA oxidase Saccharomyces cerevisiae S288C 18-22 7586025-2 1995 We have found that the FOX1 steady state mRNA level is repressed by glucose, partially induced by ethanol (but not by raffinose) and fully induced by oleic acid as a carbon source. Carbon 166-172 acyl-CoA oxidase Saccharomyces cerevisiae S288C 23-27 9555914-2 1998 The Pho84 transporter undergoes a rapid degradation once the supply of phosphate and/or carbon source is exhausted. Carbon 88-94 phosphate transporter PHO84 Saccharomyces cerevisiae S288C 4-9 25038634-1 2014 s-heptazine is one of the most attractive polycyclic C-N precursors for graphitic carbon nitride materials (CNx). Carbon 53-54 calnexin Homo sapiens 108-111 14538153-4 1998 Competition for infection sites, or for nutrients (such as carbon, iron) as well as induction of the host plant resistance, have been demonstrated for several pathogens such as Rhizoctonia spp., Fusarium spp. Carbon 59-65 histocompatibility minor 13 Homo sapiens 189-192 7785324-0 1995 Genetic and carbon source regulation of phosphorylation of Sip1p, a Snf1p-associated protein involved in carbon response in Saccharomyces cerevisiae. Carbon 12-18 Sip1p Saccharomyces cerevisiae S288C 59-64 7785324-0 1995 Genetic and carbon source regulation of phosphorylation of Sip1p, a Snf1p-associated protein involved in carbon response in Saccharomyces cerevisiae. Carbon 105-111 Sip1p Saccharomyces cerevisiae S288C 59-64 7785324-1 1995 The SIP1 gene of Saccharomyces cerevisiae is a carbon-catabolite-specific negative regulator of GAL gene transcription and acts as a multicopy suppressor of growth defects associated with impaired Snf1p protein kinase activity. Carbon 47-53 Sip1p Saccharomyces cerevisiae S288C 4-8 7785324-3 1995 We have carried out in vivo studies of the genetic and carbon control of Sip1p phosphorylation. Carbon 55-61 Sip1p Saccharomyces cerevisiae S288C 73-78 7785324-5 1995 By sodium dodecyl sulfate-polyacrylamide gel electrophoresis immunoblot assay, we detect apparent changes in Sip1p phosphorylation states in response to changes in carbon source. Carbon 164-170 Sip1p Saccharomyces cerevisiae S288C 109-114 7785324-6 1995 At least one dephosphorylation of Sip1p occurs with a shift from non-repressing carbon source to repressing carbon source. Carbon 80-86 Sip1p Saccharomyces cerevisiae S288C 34-39 7785324-6 1995 At least one dephosphorylation of Sip1p occurs with a shift from non-repressing carbon source to repressing carbon source. Carbon 108-114 Sip1p Saccharomyces cerevisiae S288C 34-39 7785324-9 1995 These results reveal new complexities in carbon response signaling, and may reflect the involvement of the Sip1 protein in the same complex as the Mig1 and Ssn6 proteins. Carbon 41-47 Sip1p Saccharomyces cerevisiae S288C 107-111 7785324-9 1995 These results reveal new complexities in carbon response signaling, and may reflect the involvement of the Sip1 protein in the same complex as the Mig1 and Ssn6 proteins. Carbon 41-47 transcription factor MIG1 Saccharomyces cerevisiae S288C 147-151 7785324-9 1995 These results reveal new complexities in carbon response signaling, and may reflect the involvement of the Sip1 protein in the same complex as the Mig1 and Ssn6 proteins. Carbon 41-47 transcription regulator CYC8 Saccharomyces cerevisiae S288C 156-160 9474769-2 1997 In the bioelectrocatalytic approach, glassy carbon electrodes were modified by laccase or a PQQ-dependent glucose dehydrogenase. Carbon 44-50 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 106-127 24448971-0 2014 FIB-SEM imaging of carbon nanotubes in mouse lung tissue. Carbon 19-25 fibrinogen alpha chain Mus musculus 0-3 7867935-6 1995 These GAL1,10-containing plasmids demonstrated appropriate regulation of the reporter in response to carbon sources. Carbon 101-107 galactokinase Saccharomyces cerevisiae S288C 6-10 24835511-0 2014 Protein imprinted ionic liquid polymer on the surface of multiwall carbon nanotubes with high binding capacity for lysozyme. Carbon 67-73 lysozyme C, tracheal isozyme Bos taurus 115-123 7969120-2 1994 Using an ethyl methanesulfonate mutant of a yeast strain in which CUP1 and ACE1 were deleted, we isolated a gene, designated CUP9, which permits yeast cells to grow at high concentrations of environmental copper, most notably when lactate is the sole carbon source. Carbon 251-257 Cup9p Saccharomyces cerevisiae S288C 125-129 7969120-5 1994 CUP9 mRNA levels were, however, down regulated by copper when yeast cells were grown with glucose but not with lactate or glycerol-ethanol as the sole carbon source. Carbon 151-157 Cup9p Saccharomyces cerevisiae S288C 0-4 9428654-1 1997 In the present study, we demonstrated that the attachment of the nonpolar isopropylic carbon chain in the nitrogen of oxamate, converted this competitive inhibitor of LDH isozymes into a powerful selective inhibitor of mouse LDH-C4. Carbon 86-92 lactate dehydrogenase A Mus musculus 167-170 24706552-1 2014 Carbonic anhydrase (CA) catalyzes the first biochemical step of the carbon-concentrating mechanism of C4 plants, and in C4 monocots it has been suggested that CA activity is near limiting for photosynthesis. Carbon 68-74 carbonic anhydrase Zea mays 0-18 9427394-1 1997 The ACS1 gene, encoding one out of two acetyl-CoA synthetase isoenzymes of Saccharomyces cerevisiae, is strictly regulated at the transcriptional level by the carbon source of the medium. Carbon 159-165 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 4-8 9427394-2 1997 While ACS1 is poorly expressed in the presence of a high glucose concentration, a several hundred-fold derepression occurs with ethanol as the sole carbon source or under conditions of sugar limitation. Carbon 148-154 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 6-10 9427394-3 1997 The molecular mechanism responsible for the carbon source control of ACS1 turned out to be highly complex. Carbon 44-50 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 69-73 7934167-3 1994 In ATL patients, a good correlation was demonstrated between the serum C-PTHrP level and serum calcium or lactic dehydrogenase (LDH) level. Carbon 71-72 parathyroid hormone like hormone Homo sapiens 73-78 24706552-1 2014 Carbonic anhydrase (CA) catalyzes the first biochemical step of the carbon-concentrating mechanism of C4 plants, and in C4 monocots it has been suggested that CA activity is near limiting for photosynthesis. Carbon 68-74 carbonic anhydrase Zea mays 20-22 7929112-1 1994 Transcription of POX1, the gene encoding peroxisomal acyl-CoA oxidase in the yeast Saccharomyces cerevisiae, is controlled by the carbon source given for cell growth. Carbon 130-136 acyl-CoA oxidase Saccharomyces cerevisiae S288C 17-21 9268358-3 1997 The Saccharomyces cerevisiae Sps19p is 34% similar to the human and rat mitochondrial reductases, and an SPS19 deleted strain was unable to utilize petroselineate (cis-C18:1(6)) as the sole carbon source, but remained viable on oleate (cis-C18:1(9)). Carbon 190-196 2,4-dienoyl-CoA reductase (NADPH) Saccharomyces cerevisiae S288C 105-110 24706552-1 2014 Carbonic anhydrase (CA) catalyzes the first biochemical step of the carbon-concentrating mechanism of C4 plants, and in C4 monocots it has been suggested that CA activity is near limiting for photosynthesis. Carbon 68-74 carbonic anhydrase Zea mays 159-161 24800942-4 2014 Enzyme inhibition studies indicate that indenoisoquinolines modified at the 2-position with three-carbon side chains ending with amino substituents show both promising Top1 and TDP1 inhibitory activity. Carbon 98-104 tyrosyl-DNA phosphodiesterase 1 Homo sapiens 177-181 9367572-3 1997 An ideal active carbon adsorbent with a BET surface area of 1236 m2/g and a total pore volume of 0.679 cm3/g has been obtained. Carbon 16-22 delta/notch like EGF repeat containing Homo sapiens 40-43 9268564-1 1997 It was shown that, although active carbons under study show appreciable differences in the BET specific surface area and the total pore volume, they exhibit quite similar porous properties. Carbon 35-42 delta/notch like EGF repeat containing Homo sapiens 91-94 24513051-2 2014 All compounds are characterized by a trans double bond located in the side chain between C-22 and C-23. Carbon 89-90 nucleolin Homo sapiens 98-102 9232194-1 1997 The disposition of whole blood mono-to hexaglutamyl methylfolate and plasma homocysteine (HCY) was used to evaluate potential lesion sites in one-carbon metabolism which could be responsible for neural tube defect(NTD)-affected pregnancies. Carbon 146-152 fuzzy planar cell polarity protein Homo sapiens 214-217 24368188-4 2014 Thus, IRF3 is a key factor controlling melanoma growth through NK-cell activities, especially during poly-I:C therapy. Carbon 108-109 interferon regulatory factor 3 Mus musculus 6-10 9134230-8 1997 We have shown that P450 enzymes model the site of general anaesthesia in the tadpole with respect to (a) an absolute sensitivity to increasing chain-length series of flexible, straight chain primary and secondary alcohols and straight chain diols, (b) an absolute sensitivity to increasing molecular weight series of rigid cyclic alkanols and cyclic alkanemethanols, (c) the points of abrupt change and of reversal (cut-off) in the linear relationship between increasing anaesthetic potency with increasing carbon chain length, and (d) non-differentiation between secondary alkanol enantiomers. Carbon 507-513 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 19-23 24598127-1 2014 Unique SnO(x) (x = 1,2)/ordered mesoporous carbon nanocomposites (denoted as SnO(x)/OMC) are firstly synthesized through a "one-pot" synthesis together with the soft template self-assembly approach. Carbon 43-49 strawberry notch homolog 1 Homo sapiens 77-80 9045801-1 1997 The expression of PRB1, the gene that encodes the precursor to the soluble vacuolar proteinase B (PrB) in Saccharomyces cerevisiae, is regulated by carbon and nitrogen sources and by growth phase. Carbon 148-154 proteinase B Saccharomyces cerevisiae S288C 18-22 9045801-1 1997 The expression of PRB1, the gene that encodes the precursor to the soluble vacuolar proteinase B (PrB) in Saccharomyces cerevisiae, is regulated by carbon and nitrogen sources and by growth phase. Carbon 148-154 proteinase B Saccharomyces cerevisiae S288C 84-96 9045801-1 1997 The expression of PRB1, the gene that encodes the precursor to the soluble vacuolar proteinase B (PrB) in Saccharomyces cerevisiae, is regulated by carbon and nitrogen sources and by growth phase. Carbon 148-154 proteinase B Saccharomyces cerevisiae S288C 98-101 24225886-7 2014 The Rs1 and Rs2 symbionts are genomically distinct in carbon and sulfur metabolism, respiration, and cell wall composition, among others. Carbon 54-60 retinoschisin 1 Homo sapiens 4-7 24580375-0 2014 Durable carbon-coated Li2(S) core-shell spheres for high performance lithium/sulfur cells. Carbon 8-14 ATP binding cassette subfamily A member 12 Homo sapiens 22-25 9057841-6 1997 Whereas region A2 contained a sequence motif similar to the carbon-source-responsive element (CSRE), which mediates regulation by carbon source of S. cerevisiae ICL1, region A1 did not show similarity to any reported cis-acting elements. Carbon 60-66 isocitrate lyase 1 Saccharomyces cerevisiae S288C 161-165 9046094-5 1997 However, this URS(SUC2) mediated repression occurs on all tested carbon sources, suggesting that this URS element acts in concert with all other promoter elements to respond to low concentrations of glucose. Carbon 65-71 beta-fructofuranosidase SUC2 Saccharomyces cerevisiae S288C 18-22 24211460-1 2014 Cholesterol oxidase (ChOx) and catalase (CAT) were co-immobilized on a graphene/ionic liquid-modified glassy carbon electrode (GR-IL/GCE) to develop a highly sensitive amperometric cholesterol biosensor. Carbon 109-115 glycine cleavage system protein H Homo sapiens 127-136 24559867-3 2014 Therefore, we screened Am580 and some related tetramethyltetrahydronaphthalene derivatives and carried out structural development studies, including substitution of carbon atoms with silicon, with the aim of creating a potent ROR transcriptional inhibitor. Carbon 165-171 long intergenic non-protein coding RNA, regulator of reprogramming Homo sapiens 226-229 9360714-3 1997 The levels of the NAM9 transcript and protein are both reduced in cells growing on glucose as compared to cells growing on galactose as a carbon source. Carbon 138-144 mitochondrial 37S ribosomal protein NAM9 Saccharomyces cerevisiae S288C 18-22 32261317-1 2014 Based on the interactions between the zinc finger protein (ZNF) and single-walled carbon nanotubes (SWCNTs), we design a nanodevice for injecting ZNF spontaneously. Carbon 82-88 zinc finger protein 763 Homo sapiens 59-62 15093403-5 1997 In addition, a smaller particle has a higher specific surface area and therefore may contain more organic carbon, which allows for more PAH adsorption. Carbon 106-112 phenylalanine hydroxylase Homo sapiens 136-139 32261317-1 2014 Based on the interactions between the zinc finger protein (ZNF) and single-walled carbon nanotubes (SWCNTs), we design a nanodevice for injecting ZNF spontaneously. Carbon 82-88 zinc finger protein 763 Homo sapiens 146-149 8981998-6 1997 The sucA mutant is not a succinate auxotroph but has a reduced ability to use glutamate as a carbon or nitrogen source and an increased sensitivity to growth inhibition by acetate, relative to the parental strain. Carbon 93-99 2-oxoglutarate dehydrogenase E1 component Bradyrhizobium diazoefficiens USDA 110 4-8 24333266-1 2014 The current study was conducted to elucidate the effect of genetic variations in one-carbon metabolism on the epigenetic regulation of major histocompatibility complex II transactivator (MHC2TA), reduced folate carrier 1 (RFC1/SLC19A1) and human leukocyte antigen (HLA)-DR in systemic lupus erythematosus (SLE). Carbon 85-91 solute carrier family 19 member 1 Homo sapiens 227-234 8943231-4 1996 Saturated 10-18-carbon and unsaturated 14-20-carbon fatty acyl-CoAs displaced SCP-2-bound fluorescent ligand. Carbon 16-22 sterol carrier protein 2 Homo sapiens 78-83 24188577-3 2014 Twelve OH-addition routes were reported, and the C atom adjacent to the ether bond in the benzene ring (RaddB1) was found as the most easily attacked position by OH, producing TCS-OHB1. Carbon 49-50 treacle ribosome biogenesis factor 1 Homo sapiens 176-184 8943231-4 1996 Saturated 10-18-carbon and unsaturated 14-20-carbon fatty acyl-CoAs displaced SCP-2-bound fluorescent ligand. Carbon 45-51 sterol carrier protein 2 Homo sapiens 78-83 8916897-2 1996 Microcalorimetric measurements confirm that the binding affinity of acyl-CoA esters for ACBP is strongly dependent on the length of the acyl chain with a clear preference for acyl-CoA esters containing more than eight carbon atoms and that the 3"-phosphate of the ribose accounts for almost half of the binding energy. Carbon 218-224 diazepam binding inhibitor, acyl-CoA binding protein Bos taurus 88-92 24287590-0 2014 Mesoporous carbon-coated LiFePO4 nanocrystals co-modified with graphene and Mg2+ doping as superior cathode materials for lithium ion batteries. Carbon 11-17 mucin 7, secreted Homo sapiens 76-79 8938419-5 1996 Potato fumarase complemented a fumarase-deficient Escherichia coli mutation for growth on minimal medium that contains acetate or fumarate as the sole carbon source, indicating that functional plant protein was produced in the bacterium. Carbon 151-157 fumarate hydratase 1, mitochondrial-like Solanum tuberosum 7-15 8938419-5 1996 Potato fumarase complemented a fumarase-deficient Escherichia coli mutation for growth on minimal medium that contains acetate or fumarate as the sole carbon source, indicating that functional plant protein was produced in the bacterium. Carbon 151-157 fumarate hydratase 1, mitochondrial-like Solanum tuberosum 31-39 8938420-9 1996 These results suggest that the induction of expression of H(+)-ATPase genes by metabolizable sugars may be part of a generalized cellular response to increased cell growth and metabolism promoted by the availability of an abundant carbon source. Carbon 231-237 plasma membrane ATPase 1 Solanum lycopersicum 58-69 8900132-10 1996 This is the first example in yeast of a complete circuit linking a stimulus (carbon source) to gene regulation (PIS1) using a two-component regulator (SLN1). Carbon 77-83 histidine kinase Saccharomyces cerevisiae S288C 151-155 23944933-6 2014 Knockdown of IL-17 receptor (IL-17R) E, the specific receptor for IL-17C, using IL-17RE small interfering RNA, attenuated polyI:C-induced hBD2, CSF3, and S100A12 expression, without any reduction of polyI:C-induced IL-17C expression, which suggest that IL-17C enhances hBD2, CSF, and S100A12 expression in an autocrine/paracrine manner in NHBE cells. Carbon 71-72 interleukin 17 receptor A Homo sapiens 13-27 21619357-4 1996 As the chain length was reduced from C-18 to C-8 and C-4, the rate of diffusion also decreased. Carbon 37-38 homeobox C8 Homo sapiens 45-48 23944933-6 2014 Knockdown of IL-17 receptor (IL-17R) E, the specific receptor for IL-17C, using IL-17RE small interfering RNA, attenuated polyI:C-induced hBD2, CSF3, and S100A12 expression, without any reduction of polyI:C-induced IL-17C expression, which suggest that IL-17C enhances hBD2, CSF, and S100A12 expression in an autocrine/paracrine manner in NHBE cells. Carbon 71-72 interleukin 17 receptor A Homo sapiens 29-35 23944933-6 2014 Knockdown of IL-17 receptor (IL-17R) E, the specific receptor for IL-17C, using IL-17RE small interfering RNA, attenuated polyI:C-induced hBD2, CSF3, and S100A12 expression, without any reduction of polyI:C-induced IL-17C expression, which suggest that IL-17C enhances hBD2, CSF, and S100A12 expression in an autocrine/paracrine manner in NHBE cells. Carbon 128-129 interleukin 17 receptor A Homo sapiens 13-27 23944933-6 2014 Knockdown of IL-17 receptor (IL-17R) E, the specific receptor for IL-17C, using IL-17RE small interfering RNA, attenuated polyI:C-induced hBD2, CSF3, and S100A12 expression, without any reduction of polyI:C-induced IL-17C expression, which suggest that IL-17C enhances hBD2, CSF, and S100A12 expression in an autocrine/paracrine manner in NHBE cells. Carbon 128-129 interleukin 17 receptor A Homo sapiens 29-35 8702805-8 1996 Calmodulin binding to the recombinant reductase protein increased its rate of NADPH-dependent flavin reduction and its rate of electron transfer to cytochrome c, FeCN6, or dichlorophenolindophenol to fully match the rate increases achieved when calmodulin bound to native full-length nNOS. Carbon 28-29 calmodulin 1 Rattus norvegicus 0-10 8702805-8 1996 Calmodulin binding to the recombinant reductase protein increased its rate of NADPH-dependent flavin reduction and its rate of electron transfer to cytochrome c, FeCN6, or dichlorophenolindophenol to fully match the rate increases achieved when calmodulin bound to native full-length nNOS. Carbon 28-29 calmodulin 1 Rattus norvegicus 245-255 25743342-7 2014 Consequently, 14- to 22-carbon unsaturated LCFAs showed strong GPR120-agonistic activity. Carbon 24-30 free fatty acid receptor 4 Mus musculus 63-69 23821251-3 2014 BET surface area of the activated carbon was determined as 558 m(2)/g. Carbon 34-40 delta/notch like EGF repeat containing Homo sapiens 0-3 8647275-0 1996 Fractionation of carbon (13C/12C) isotopes in glycine decarboxylase reaction. Carbon 17-23 glycine decarboxylase Homo sapiens 46-67 8647275-1 1996 Fractionation of carbon isotopes (13C/12C) by glycine decarboxylase (GDC) was investigated in mitochondrial preparations isolated from photosynthetic tissues of different plants (Pisum, Medicago, Triticum, Hordeum, Spinacia, Brassica, Wolffia). Carbon 17-23 glycine decarboxylase Homo sapiens 46-67 8647275-1 1996 Fractionation of carbon isotopes (13C/12C) by glycine decarboxylase (GDC) was investigated in mitochondrial preparations isolated from photosynthetic tissues of different plants (Pisum, Medicago, Triticum, Hordeum, Spinacia, Brassica, Wolffia). Carbon 17-23 glycine decarboxylase Homo sapiens 69-72 8647275-5 1996 Carbon isotope effects were sensitive to reaction conditions (pH and the presence of GDC cofactors). Carbon 0-6 glycine decarboxylase Homo sapiens 85-88 24312611-0 2013 PLGA-carbon nanotube conjugates for intercellular delivery of caspase-3 into osteosarcoma cells. Carbon 5-11 caspase 3 Bos taurus 62-71 8647275-7 1996 Therefore, the fractionation of carbon isotopes in GDC reaction was revealed which provides essential isotopic effects in plants in addition to the well-known effect of carbon isotope fractionation by the central photosynthetic enzyme, ribulose-1,5-biphosphate carboxylase. Carbon 32-38 glycine decarboxylase Homo sapiens 51-54 8647275-7 1996 Therefore, the fractionation of carbon isotopes in GDC reaction was revealed which provides essential isotopic effects in plants in addition to the well-known effect of carbon isotope fractionation by the central photosynthetic enzyme, ribulose-1,5-biphosphate carboxylase. Carbon 169-175 glycine decarboxylase Homo sapiens 51-54 8662598-5 1996 When this yeast is grown in medium containing oleic acid as the main carbon source, peroxisomes are induced and POX1 expression is activated. Carbon 69-75 acyl-CoA oxidase Saccharomyces cerevisiae S288C 112-116 8620865-3 1996 & Tatchell, K. (1986) Genetics 113, 247-264] by selection of ras2::LEU2 revertants that grew on non-fermentable carbon sources. Carbon 116-122 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 65-69 21619081-7 1996 For the five biphasic solvent systems studied, linear relationships were found between the partition coefficients and the sp(3) and sp(2) hybridized carbon atom number for the alkylbenzene and PAH series, respectively. Carbon 149-155 phenylalanine hydroxylase Homo sapiens 193-196 7803857-2 1994 Yeast lacking Yme1p lose DNA from mitochondria at an accelerated rate, fail to grow on nonfermentable carbon sources at 37 degrees C, and have severely deficient growth if mitochondrial DNA suffers large deletions or is completely lost. Carbon 102-108 i-AAA protease YME1 Saccharomyces cerevisiae S288C 14-19 24106106-0 2013 Amythiamicin D and related thiopeptides as inhibitors of the bacterial elongation factor EF-Tu: modification of the amino acid at carbon atom C2 of ring C dramatically influences activity. Carbon 130-136 AT695_RS01290 Staphylococcus aureus 89-94 8196607-0 1994 A carbon source-responsive promoter element necessary for activation of the isocitrate lyase gene ICL1 is common to genes of the gluconeogenic pathway in the yeast Saccharomyces cerevisiae. Carbon 2-8 isocitrate lyase 1 Saccharomyces cerevisiae S288C 98-102 8688560-1 1996 Inactivation of YME1 in yeast causes several distinct phenotypes: an increased rate of DNA escape from mitochondria, temperature-sensitive growth on nonfermentable carbon sources, extremely slow growth when mitochondrial DNA is completely absent from the cell, and altered morphology of the mitochondrial compartment. Carbon 164-170 i-AAA protease YME1 Saccharomyces cerevisiae S288C 16-20 8196607-3 1994 Deletion analysis of the ICL1 promoter led to the identification of an upstream activating sequence element, UASICL1 (5" CATTCATCCG 3"), necessary and sufficient for conferring carbon source-dependent regulation on a heterologous reporter gene. Carbon 177-183 isocitrate lyase 1 Saccharomyces cerevisiae S288C 25-29 23916769-4 2013 pRB has been shown to regulate glucose tolerance, mitogenesis, glutathione synthesis, and the expression of genes involved in central carbon metabolism. Carbon 134-140 RB transcriptional corepressor 1 Homo sapiens 0-3 8157982-5 1994 Visualization of these reactive regions on a three-dimensional computer-generated carbon PR3 trace diagram showed that one aspect of the molecule on the inferolateral surface comprised most of the antigenic regions. Carbon 82-88 proteinase 3 Homo sapiens 89-92 7578007-0 1995 Mechanistic kinship between hydroxylation and desaturation reactions: acyl-carbon bond cleavage promoted by pig and human CYP17 (P-450(17)alpha; 17 alpha-hydroxylase-17,20-lyase). Carbon 75-81 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 122-127 24057859-7 2013 In our present study, sheep PBMCs had significantly higher TLR3 mRNA levels, TLR3 specific ligand (Poly I:C) stimulation resulted in increased levels of IFN-gamma at transcriptional and translational levels along with IL-8 and IL-10 at transcriptional levels. Carbon 31-32 toll-like receptor 3 Ovis aries 59-63 11379054-20 1995 Although the 6-carbon and 9-carbon cis-3-aldehydes could be synthesized from the cis-3-alcohols, the resulting aldehydes were not chemically stable. Carbon 15-21 suppressor of cytokine signaling 3 Homo sapiens 81-86 7676479-6 1995 A finer analysis was made of a series of A-ring phenols showing the high degree of glucocorticoid receptor and progesterone receptor binding that can be generated by certain C-11-substitutions despite the presence of the phenolic A-ring characteristic of estrogen receptor-specific binding. Carbon 174-175 progesterone receptor Homo sapiens 111-132 7758459-11 1995 Our results indicate that these sequences mediate the effects of the respective transactivator on the oxygen- and carbon-source-dependent transcription of the AAC2 gene. Carbon 114-120 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 159-163 8145237-10 1994 In contrast, the aryl carbon atoms ortho to the phenolic group of APAP approach closer to the heme iron of CYP2B1 (3.19 +/- 0.12 A) than to the heme iron of CPY1A1 (3.66 +/- 0.30 A). Carbon 22-28 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 107-113 24057859-7 2013 In our present study, sheep PBMCs had significantly higher TLR3 mRNA levels, TLR3 specific ligand (Poly I:C) stimulation resulted in increased levels of IFN-gamma at transcriptional and translational levels along with IL-8 and IL-10 at transcriptional levels. Carbon 31-32 toll-like receptor 3 Ovis aries 77-81 7764306-7 1994 Also, there are five consensus 5"-(G/C)PyGGGG-3" sequences that have been identified to be carbon catabolite repressor binding sites of Aspergillus nidulans CREA and Saccharomyces cerevisiae MIG1 repressors. Carbon 91-97 transcription factor MIG1 Saccharomyces cerevisiae S288C 191-195 24160919-2 2013 In the formation of the male hormone dehydroepiandrosterone, pregnenolone is first hydroxylated by P450 CYP17A1 at the 17-carbon, followed a second round of catalysis by the same enzyme that cleaves the C17-C20 bond, releasing acetic acid and the 17-keto product. Carbon 122-128 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 104-111 8117053-5 1993 The mean fall in blood pressure on ABPM (SBP, DBP, mean of 24-hour recording, diurnal and nocturnal) at 4 weeks was greater with L/HCTZ than with C/HCTZ. Carbon 132-133 selenium binding protein 1 Homo sapiens 41-44 7730379-4 1995 The qsr mutants require QCR6 for viability on fermentable and non-fermentable carbon sources, indicating that QCR6 is covering lethal mutations in qsr1 and qsr2, even when the yeast do not require respiration. Carbon 78-84 ubiquinol--cytochrome-c reductase subunit 6 Saccharomyces cerevisiae S288C 110-114 7562952-3 1995 Pyruvate carboxylase plays a pivotal role in gluconeogenesis and in supplying carbon units for the citric acid cycle. Carbon 78-84 pyruvate carboxylase Mus musculus 0-20 23494399-0 2013 Construction of an improved amperometric acrylamide biosensor based on hemoglobin immobilized onto carboxylated multi-walled carbon nanotubes/iron oxide nanoparticles/chitosan composite film. Carbon 125-131 hemoglobin Solanum tuberosum 71-81 8358742-0 1993 Proton and carbon NMR chemical-shift assignments for [beta-D-Fru f-(2-->1)]3-(2<==>1)-alpha-D-Glc p (nystose) and [beta-D-Fru f-(2-->1)]4-(2<==>1)-alpha-D-Glc p (1,1,1-kestopentaose) from two-dimensional NMR spectral measurements. Carbon 11-17 zinc finger and BTB domain containing 22 Homo sapiens 61-64 8358742-0 1993 Proton and carbon NMR chemical-shift assignments for [beta-D-Fru f-(2-->1)]3-(2<==>1)-alpha-D-Glc p (nystose) and [beta-D-Fru f-(2-->1)]4-(2<==>1)-alpha-D-Glc p (1,1,1-kestopentaose) from two-dimensional NMR spectral measurements. Carbon 11-17 zinc finger and BTB domain containing 22 Homo sapiens 131-134 23494399-1 2013 A method is described for construction of an improved amperometric acrylamide biosensor based on covalent immobilization of hemoglobin (Hb) onto nanocomposite of carboxylated multi-walled carbon nanotubes (cMWCNT) and iron oxide nanoparticles (Fe3O4NPs) electrodeposited onto Au electrode through chitosan (CHIT) film. Carbon 188-194 hemoglobin Solanum tuberosum 124-134 23966327-2 2013 PLP plays many roles, including in one-carbon metabolism for the acquisition and transfer of carbon units and in the transsulfuration pathway. Carbon 39-45 pyridoxal phosphatase Homo sapiens 0-3 8104116-8 1993 Because delta 2(E)-VPA is known to be formed from VPA-CoA through the action of 2-methyl-branched-chain acyl-CoA dehydrogenase, it is proposed that the three-carbon side-chains of both parent drug and delta 2(E)-VPA are interconverted as a consequence of reversibility in the second half-reaction of this enzymatic process. Carbon 158-164 acyl-CoA dehydrogenase, short/branched chain Rattus norvegicus 80-126 7897657-1 1995 The DNA methyltransferases, M.HhaI and M.TaqI, and catechol O-methyl-transferase (COMT) catalyze the transfer of a methyl group from the cofactor S-adenosyl-L-methionine (AdoMet) to carbon-5 of cytosine, to nitrogen-6 of adenine, and to a hydroxyl group of catechol, respectively. Carbon 182-188 catechol-O-methyltransferase Homo sapiens 51-80 7897657-1 1995 The DNA methyltransferases, M.HhaI and M.TaqI, and catechol O-methyl-transferase (COMT) catalyze the transfer of a methyl group from the cofactor S-adenosyl-L-methionine (AdoMet) to carbon-5 of cytosine, to nitrogen-6 of adenine, and to a hydroxyl group of catechol, respectively. Carbon 182-188 catechol-O-methyltransferase Homo sapiens 82-86 23966327-2 2013 PLP plays many roles, including in one-carbon metabolism for the acquisition and transfer of carbon units and in the transsulfuration pathway. Carbon 93-99 pyridoxal phosphatase Homo sapiens 0-3 23642096-0 2013 Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes. Carbon 94-100 prostaglandin-endoperoxide synthase 2 Mus musculus 8-24 7765813-1 1994 Pseudomonas MA3 was isolated from activated sludge on the basis of its capacity to use dodecyldimethylamine as a sole carbon (C) and energy source. Carbon 118-124 PNMA family member 3 Homo sapiens 12-15 8517874-6 1993 These data suggested that substitution of fluorines for hydrogens at C-26 and at C-27 positions may result in alteration in chemical reactivity and/or conformation of C-23, C-24 and C-25 positions of the 1,25-(OH)2D3 molecule. Carbon 69-70 nucleolin Homo sapiens 167-171 8517874-6 1993 These data suggested that substitution of fluorines for hydrogens at C-26 and at C-27 positions may result in alteration in chemical reactivity and/or conformation of C-23, C-24 and C-25 positions of the 1,25-(OH)2D3 molecule. Carbon 81-82 nucleolin Homo sapiens 167-171 23924264-0 2013 Chronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix metalloproteinase-2. Carbon 20-26 matrix metallopeptidase 2 Homo sapiens 89-115 8346678-5 1993 Expression of HEM6 (HEM12) was investigated and was found to increase two-fold in a non-fermentable carbon source. Carbon 100-106 uroporphyrinogen decarboxylase HEM12 Saccharomyces cerevisiae S288C 14-18 8474461-1 1993 The concentration of the transcriptional activator LAC9 (KlGAL4) of Kluyveromyces lactis is moderately regulated by the carbon source as is the case for GAL4, its homolog in Saccharomyces cerevisiae. Carbon 120-126 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 59-63 7997158-8 1994 Pretreatment of the target tissues with Proteinase K decreased the gonococcal binding dramatically, whereas pretreatment with neuraminidase and meta-periodate, which cleave carbon-carbon linkages between vicinal hydroxyl groups in carbohydrates, did not affect attachment of gonococci. Carbon 173-179 neuraminidase 1 Homo sapiens 126-139 7997158-8 1994 Pretreatment of the target tissues with Proteinase K decreased the gonococcal binding dramatically, whereas pretreatment with neuraminidase and meta-periodate, which cleave carbon-carbon linkages between vicinal hydroxyl groups in carbohydrates, did not affect attachment of gonococci. Carbon 180-186 neuraminidase 1 Homo sapiens 126-139 23943618-8 2013 Altered PP2A methylation following expression of a catalytically inactive LCMT1 mutant, knockdown of LCMT1, or alterations in one-carbon metabolism all result in a loss of plasma membrane-associated PP2A and Tau in N2a cells. Carbon 130-136 protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform Mus musculus 199-203 12232263-7 1994 These results indicate that light-driven redox modulation of G6PDH and PRK is more than an on/off switch, but acts to optimize the reduction and oxidation of carbon in the chloroplast in accordance with the supply of electrons. Carbon 158-164 uncharacterized protein Chlamydomonas reinhardtii 61-66 8096832-3 1993 The number of blood vessel profiles labelled with carbon was increased by hCG in both types of testes, but the response was more sustained in abdominal than in scrotal testes. Carbon 50-56 hypertrichosis 2 (generalised, congenital) Homo sapiens 74-77 24013316-2 2013 DISCUSSION: The beneficial effect of periconceptional folic acid on NTD prevention denotes a vital role for the single-carbon biochemical pathway in NTD genesis. Carbon 119-125 fuzzy planar cell polarity protein Homo sapiens 68-71 8088514-6 1994 Multicopy SIP1 gene reduces GAL1, GAL2, GAL7 and GAL10 gene expression three- to fourfold in cells grown in the presence of glucose but has no effect in cells grown on nonrepressing carbon. Carbon 182-188 Sip1p Saccharomyces cerevisiae S288C 10-14 8088514-9 1994 Northern analysis revealed two SIP1 transcripts whose relative abundance changed with carbon source. Carbon 86-92 Sip1p Saccharomyces cerevisiae S288C 31-35 24013316-2 2013 DISCUSSION: The beneficial effect of periconceptional folic acid on NTD prevention denotes a vital role for the single-carbon biochemical pathway in NTD genesis. Carbon 119-125 fuzzy planar cell polarity protein Homo sapiens 149-152 8195189-4 1994 Disruption of SDH3 shows that this gene is required for growth on non-fermentable carbon sources. Carbon 82-88 succinate dehydrogenase cytochrome b subunit SDH3 Saccharomyces cerevisiae S288C 14-18 7678400-4 1993 It was found that C-18 hydroxyl analogues of ascomycin, an analogue of FK-506 also called FR900520, bound tightly to immunophilin FKBP-12, but do not show any immunosuppressive activity in vitro or in vivo despite good bioavailability. Carbon 18-19 FKBP prolyl isomerase 1A Homo sapiens 117-137 23850620-10 2013 In contrast, in response to poly(I:C), Cox2(-/-) mice exhibited enhanced plasma interferon (IFNalpha,beta,gamma,lambda) and related cytokine responses (IP-10, IL-12). Carbon 35-36 cytochrome c oxidase II, mitochondrial Mus musculus 39-43 18601259-1 1993 The theoretical yield of poly-D(-)-3-hydroxybutyrate (PHB) has been estimated from the biochemical pathway leading to PHB when a carbohydrate (glucose), a C(1) compound (methanol), a C(2) compound (acetic acid), or a C(4) compound (butyric acid) is used as a carbon source. Carbon 259-265 prohibitin 1 Homo sapiens 25-52 18601259-1 1993 The theoretical yield of poly-D(-)-3-hydroxybutyrate (PHB) has been estimated from the biochemical pathway leading to PHB when a carbohydrate (glucose), a C(1) compound (methanol), a C(2) compound (acetic acid), or a C(4) compound (butyric acid) is used as a carbon source. Carbon 259-265 prohibitin 1 Homo sapiens 54-57 23850620-10 2013 In contrast, in response to poly(I:C), Cox2(-/-) mice exhibited enhanced plasma interferon (IFNalpha,beta,gamma,lambda) and related cytokine responses (IP-10, IL-12). Carbon 35-36 chemokine (C-X-C motif) ligand 10 Mus musculus 152-157 23552844-0 2013 MOF@activated carbon: a new material for adsorption of aldicarb in biological systems. Carbon 14-20 lysine acetyltransferase 8 Homo sapiens 0-3 8205063-1 1993 Ion beam assisted diamond-like carbon (DLC) films have been used for growing the human hematopoietic myeloblastic ML-1 cells and human embryo kidney 293 cells in the control environment. Carbon 31-37 interleukin 17F Homo sapiens 114-118 8206851-4 1994 Hxt2p was not expressed by wild-type S. cerevisiae in media containing only ethanol or galactose as carbon and energy source but was expressed if glucose was added. Carbon 100-106 hexose transporter HXT2 Saccharomyces cerevisiae S288C 0-5 8206851-5 1994 An hxk2-delta 1::URA3 mutant did not detectably express Hxt2p in ethanol or galactose, but an ssn6-delta9 mutant did highly express Hxt2p in both carbon sources. Carbon 146-152 transcription regulator CYC8 Saccharomyces cerevisiae S288C 94-105 23716305-3 2013 The resulting active carbon material that is derived from ZIF-70, that is, FeNC-70, exhibits the highest BET surface area of 262 m(2) g(-1) compared to the active carbon materials that are derived from ZIF-68 and ZIF-69. Carbon 21-27 delta/notch like EGF repeat containing Homo sapiens 105-108 8198542-7 1994 Examination of the fatty acid specificity showed that a minimal chain length of 16 carbon atoms and the presence of at least one double bond, preferably in a cis configuration, were required for inhibition of the fibrinolytic activity of plasmin. Carbon 83-89 plasminogen Homo sapiens 238-245 7512380-0 1994 Acylation of myelin basic protein peptide 1-21 with alkyl carboxylates 2-10 carbons long affects secondary structure and posttranslational modification. Carbon 76-83 myelin basic protein Homo sapiens 13-33 8278495-1 1993 We report here effects of three environmental conditions, heat shock, anaerobic treatment, and carbon source supply, on expression of nuclear genes encoding chloroplast (GapA and GapB) and cytosolic (GapC) glyceraldehyde-3-phosphate dehydrogenase from Arabidopsis thaliana. Carbon 95-101 glyceraldehyde 3-phosphate dehydrogenase A subunit Arabidopsis thaliana 170-246 8285068-2 1993 III was established as the epimer of I and IV, as a new type of head-to-tail bisbenzylisoquinoline alkaloid with two diarylether bridges in between C-8 to C-12" and C-12 to C-7" on the basis of physical constants and spectral data (UV, IR, EIMS, 1HNMR and NOEDS). Carbon 155-156 homeobox C8 Homo sapiens 148-151 23508663-8 2013 Lastly, chlorophyll a fluorescence revealed a significant decrease in PhiPSII and q L in atprx72 mutant plants that could be related to changes in carbon partitioning and/or utilization of redox equivalents in arabidopsis metabolism. Carbon 147-153 Peroxidase superfamily protein Arabidopsis thaliana 89-96 1433514-2 1992 An antibody (C"-B5R) raised to a 15-amino-acid peptide from the translated B5R ORF reacted with a 42-kDa protein (gp42) found in vaccinia virus-infected cells and cesium chloride-banded EEV but not INV. Carbon 13-15 cytochrome b5 reductase 3 Homo sapiens 16-19 1433514-2 1992 An antibody (C"-B5R) raised to a 15-amino-acid peptide from the translated B5R ORF reacted with a 42-kDa protein (gp42) found in vaccinia virus-infected cells and cesium chloride-banded EEV but not INV. Carbon 13-15 cytochrome b5 reductase 3 Homo sapiens 75-78 8177217-2 1994 We have demonstrated that the transcriptional co-activator GAL11, which was identified as an auxiliary factor to GAL4 and which is believed to interact with the zinc finger of the trans-activator, positively influences the level of PGK transcription on both fermentable and non-fermentable carbon sources. Carbon 290-296 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 113-117 23519143-3 2013 A masked glucose precursor that is activated by beta-galactosidase was used as a carbon source for bacterial growth in a glucose-deficient medium. Carbon 81-87 galactosidase beta 1 Homo sapiens 48-66 8152421-3 1994 Deletion analysis of the CYB3 promoter identified a single HAP2/3/4-binding element that is necessary and sufficient for carbon source-dependent transcriptional regulation. Carbon 121-127 succinate dehydrogenase cytochrome b subunit SDH3 Saccharomyces cerevisiae S288C 25-29 1512188-2 1992 The recessive single nuclear gene mutation, named gcr3, caused an extremely defective growth phenotype on fermentable carbon sources such as glucose, while growth on respiratory media was almost normal. Carbon 118-124 Sto1p Saccharomyces cerevisiae S288C 50-54 23402795-6 2013 In particular, we found that several genes in the glutamate receptor signaling pathway, including Gria1 and Slc17a7, showed decreases in promoter-specific histone acetylation, and corresponding gene expression deficits, in polyI:C-exposed offspring at both juvenile and adult ages. Carbon 229-230 glutamate receptor, ionotropic, AMPA1 (alpha 1) Mus musculus 98-103 1630920-7 1992 Elimination of this DNA sequence results in constitutive expression of POX1 when S. cerevisiae is grown on a fermentable carbon source or glycerol. Carbon 121-127 acyl-CoA oxidase Saccharomyces cerevisiae S288C 71-75 8204822-13 1994 Among these, an Opaque2 and a yeast GCN4-like recognition element might be relevant for such a gene coding for an enzyme limiting the carbon-flux entry to the biosynthesis of several essential amino acids. Carbon 134-140 amino acid starvation-responsive transcription factor GCN4 Saccharomyces cerevisiae S288C 36-40 23494916-1 2013 Supercapacitors based on activated carbon prepared from various pollens show good specific capacitance (207 F g(-1) ) and large gravimetric and volumetric energy density (~88 Wh kg(-1) and ~44 Wh L(-1) , respectively) in ionic liquid electrolytes, which are much better than those of RP20 (commercial activated carbon) or graphene-based supercapacitors. Carbon 35-41 retinoid isomerohydrolase RPE65 Homo sapiens 284-288 8117110-1 1994 Biotin synthase catalyzes the insertion of a sulfur atom between two carbon atoms of dethiobiotin to form biotin in the last step of the biotin biosynthesis pathway. Carbon 69-75 biotin synthase Saccharomyces cerevisiae S288C 0-15 1495480-5 1992 Disruption of the NPK1 gene impedes neither growth on glucose or a variety of other carbon sources, nor mating or sporulation. Carbon 84-90 serine/threonine protein kinase KIN3 Saccharomyces cerevisiae S288C 18-22 11538087-4 1991 This value is two orders of magnitude less than the abundance of the related carbon-chain molecule CCS, and about half that of C3O. Carbon 77-83 copper chaperone for superoxide dismutase Homo sapiens 99-102 7929614-3 1994 Amylin therefore appears to have the effect of transposing carbon from peripheral stores to the liver, where it is made available for hepatic synthesis of glucose, glycogen, and lipid. Carbon 59-65 islet amyloid polypeptide Homo sapiens 0-6 23357280-4 2013 In FAS knockdown cells glucose carbon incorporation into lipids and the levels of the subclasses of phospholipids and cholesterol ester species were lower by 20-30% without inhibition of glucose oxidation. Carbon 31-37 fatty acid synthase Rattus norvegicus 3-6 2043148-4 1991 The results suggest that (1) microsomal ALDH is a member of the Class 3 aldehyde dehydrogenase family, and (2) the physiological role of the Class 3 ALDHs, including the microsomal form, is the oxidation of medium (6 to 9 carbon) chain length saturated and unsaturated aldehydes generated by the peroxidation of cellular lipids. Carbon 222-228 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 40-44 1993209-2 1991 5-Deazatetrahydrofolate was as good an inhibitor of GARFT as DDATHF, indicating that isosteric replacement of nitrogen by carbon at the 5-position of tetrahydrofolate is sufficient for inhibition of GARFT. Carbon 122-128 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Homo sapiens 52-57 8257702-9 1993 For Lp(a), a low pH caused a marked decrease in inhibition by the 5-carbon and 4-carbon omega-amino acids. Carbon 68-74 lipoprotein(a) Homo sapiens 4-9 23537043-1 2013 BACKGROUND: Finely regulating the carbon flux through the glycerol pathway by regulating the expression of the rate controlling enzyme, glycerol-3-phosphate dehydrogenase (GPDH), has been a promising approach to redirect carbon from glycerol to ethanol and thereby increasing the ethanol yield in ethanol production. Carbon 34-40 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 136-170 8275502-1 1993 2,6-Dihydropyran-3-ones carrying substituents at C-2 and C-6 in cis-arrangement invariably adopt half-chair conformations in which the ring oxygen and the carbon atom next to the carbonyl group are above and below, respectively, the plane formed by the other four carbon atoms, i.e., the 2Ho or oH2 conformation. Carbon 155-161 complement C6 Homo sapiens 57-60 1993209-2 1991 5-Deazatetrahydrofolate was as good an inhibitor of GARFT as DDATHF, indicating that isosteric replacement of nitrogen by carbon at the 5-position of tetrahydrofolate is sufficient for inhibition of GARFT. Carbon 122-128 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Homo sapiens 199-204 1993209-9 1991 We conclude that the presence of carbon at the 5-position of tetrahydrofolate analogues is sufficient for inhibition of GARFT, that N-8 and the 2-amino group are involved in binding of DDATHF to GARFT, probably through hydrogen bonds, and that the structures of the phenyl ring and amino acid side chain of DDATHF analogues are not primary determinants of GARFT inhibition by monoglutamate forms of these compounds. Carbon 33-39 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Homo sapiens 120-125 1993209-9 1991 We conclude that the presence of carbon at the 5-position of tetrahydrofolate analogues is sufficient for inhibition of GARFT, that N-8 and the 2-amino group are involved in binding of DDATHF to GARFT, probably through hydrogen bonds, and that the structures of the phenyl ring and amino acid side chain of DDATHF analogues are not primary determinants of GARFT inhibition by monoglutamate forms of these compounds. Carbon 33-39 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Homo sapiens 195-200 1990285-7 1991 Having proposed that regulation of 3" end formation dictates the amount of each CBP1 transcript, we now show that a 146-bp fragment from the middle of CBP1 is sufficient to direct carbon source-regulated production of two transcripts when inserted into the yeast URA3 gene. Carbon 180-186 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 263-267 8275502-1 1993 2,6-Dihydropyran-3-ones carrying substituents at C-2 and C-6 in cis-arrangement invariably adopt half-chair conformations in which the ring oxygen and the carbon atom next to the carbonyl group are above and below, respectively, the plane formed by the other four carbon atoms, i.e., the 2Ho or oH2 conformation. Carbon 179-185 complement C6 Homo sapiens 57-60 23448229-2 2013 The resulting carbon composites are characterized by FE-SEM, TEM, TGA, FTIR microspectroscopy, and nitrogen sorption techniques. Carbon 14-20 T-box transcription factor 1 Homo sapiens 66-69 8224185-2 1993 In Northern blot analyses we first showed that the steady-state ICL1 mRNA levels depend on the carbon source used for growth. Carbon 95-101 isocitrate lyase 1 Saccharomyces cerevisiae S288C 64-68 23745403-3 2013 The results showed that the average COD and color were 55.4 mg x L(-1) and 12.6 times at the height of 1500 mm in activated carbon BAF, and were 55.6 mg x L(-1) and 9.4 times at the height of 1 800 mm in composite BAF, both of the effluent at each height met the first level B criteria specified in the Discharge Standard of Pollutants for Municipal Wastewater Treatment Plant (GB 18918-2002). Carbon 124-130 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 36-39 8256514-5 1993 Finally, when cells were grown on a variety of carbon sources, the amount of ATPase polypeptide was proportional to the specific growth rate, suggesting that PMA1 expression is adjusted according to the metabolic state of the cell. Carbon 47-53 H(+)-exporting P2-type ATPase PMA1 Saccharomyces cerevisiae S288C 158-162 8367458-3 1993 We have found that in addition to these known phenotypes, SOD1-deletion strains fail to grow on agar containing the respiratory carbon source lactate. Carbon 128-134 superoxide dismutase SOD1 Saccharomyces cerevisiae S288C 58-62 23745403-5 2013 In activated carbon BAF and composite BAF, COD and ammonia nitrogen were both greatly decreased at the height of 1 200 mm, then decreased slowly. Carbon 13-19 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 43-46 23620996-1 2013 An amperometric biosensor for determination of Cytochrome c (Cyt c) was fabricated by immobilizing Cytochrome c oxidase (COx) onto nickel oxide nanoparticles (NiO-NPs) decorated carboxylated multiwalled carbon nanotubes/polyaniline (NiO-NPs/cMWCNT/PANI) film electrodeposited on the surface of a gold (Au) electrode. Carbon 203-209 cytochrome c oxidase subunit 8A Homo sapiens 121-124 23384041-7 2013 In particular, whereas the cer2 mutation impaired the production of wax components longer than 28 carbons, the cer26 mutant was found to be affected in the production of wax components longer than 30 carbons. Carbon 98-105 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 27-31 8513801-3 1993 In paracatalytically modified fructose-1,6-bisphosphate aldolase from rabbit muscle the polypeptide chain had been found to be crosslinked at active-site Lys229 (Schiff base forming with substrate) and Lys146 by a phosphorylated three-carbon moiety [Lubini, D. G. E. and Christen, P. (1979) Proc. Carbon 235-241 fructose-bisphosphate aldolase B Oryctolagus cuniculus 30-64 23384041-7 2013 In particular, whereas the cer2 mutation impaired the production of wax components longer than 28 carbons, the cer26 mutant was found to be affected in the production of wax components longer than 30 carbons. Carbon 200-207 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 111-116 8319292-3 1993 Construction of icl1 null mutants led to growth defects on C2 carbon sources while utilization of sugars or C3 substrates remained unaffected. Carbon 62-68 isocitrate lyase 1 Saccharomyces cerevisiae S288C 16-20 23384041-9 2013 Furthermore, ectopic expression of CER26 in transgenic plants demonstrates that CER26 facilitates the elongation of the very long chain fatty acids of 30 carbons or more, with high tissular and substrate specificity. Carbon 154-161 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 35-40 23384041-9 2013 Furthermore, ectopic expression of CER26 in transgenic plants demonstrates that CER26 facilitates the elongation of the very long chain fatty acids of 30 carbons or more, with high tissular and substrate specificity. Carbon 154-161 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 80-85 23387946-2 2013 This study reports the carbon acidities of Calpha and C4" atoms in the Schiff bases of pyridoxal-5"-phosphate (PLP) and pyridoxamine-5"-phosphate (PMP) complexed with several biologically available metal ions (Mg2+, Ni2+, Zn2+, Cu2+, Al3+, and Fe3+). Carbon 23-29 pyridoxal phosphatase Homo sapiens 111-114 8491733-4 1993 In yeast cells, only three mitochondrial proteins are known to have the MAK3 acetylation signal, suggesting an explanation for the slow growth of mak3 mutants on nonfermentable carbon sources. Carbon 177-183 peptide alpha-N-acetyltransferase MAK3 Saccharomyces cerevisiae S288C 72-76 8491733-4 1993 In yeast cells, only three mitochondrial proteins are known to have the MAK3 acetylation signal, suggesting an explanation for the slow growth of mak3 mutants on nonfermentable carbon sources. Carbon 177-183 peptide alpha-N-acetyltransferase MAK3 Saccharomyces cerevisiae S288C 146-150 23363050-2 2013 These cyanoalkyl donors 1 form all-carbon quaternary centers in a catalytic, asymmetric, and intermolecular manner uniquely using diamidophosphite ligands L2 and L3, generating synthetically important chiral building blocks in good yields and selectivities. Carbon 35-41 immunoglobulin kappa variable 3-15 Homo sapiens 155-164 8467796-1 1993 The Saccharomyces cerevisiae transcriptional activator GAL4 is regulated by the presence of available carbon sources. Carbon 102-108 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 55-59 23383740-1 2013 Thermal contributions to the free energy have to be taken into account to rationalize the formation of Gd(3)N@C(s)(39663)-C(82), a nitride endohedral metallofullerene that shows a carbon cage with two fused pentagons which is not predicted to have the lowest electronic energy among the isomers of C(82). Carbon 180-186 complement C8 beta chain Homo sapiens 122-127 18601259-0 1993 Yield of poly-D(-)-3-hydroxybutyrate from various carbon sources: a theoretical study. Carbon 50-56 prohibitin 1 Homo sapiens 9-36 23383740-1 2013 Thermal contributions to the free energy have to be taken into account to rationalize the formation of Gd(3)N@C(s)(39663)-C(82), a nitride endohedral metallofullerene that shows a carbon cage with two fused pentagons which is not predicted to have the lowest electronic energy among the isomers of C(82). Carbon 180-186 complement C8 beta chain Homo sapiens 298-303 22906713-2 2013 By combining laccase with catalase enzymes electrophoretically deposited by means of AC electric fields on multiple walled carbon nanotubes modified platinum black and, then stabilized by an outer layer of polypyrrole in the construction of GC/MWCNTs/Ptb/LAc-CAt/PPy biocathode, we can take advantage of the H(2)O(2) present in the solution or body tissue to increase the level of the dissolved O(2). Carbon 123-129 pancreatic polypeptide Homo sapiens 263-266 1479360-2 1992 The gene is essential for manifestation of resistance to the antibiotic polymyxin B. Deletion of PBS2 enables a ras2-530 null mutant to grow on nonfermentable carbon sources; overexpression of PBS2+ enhances viability of a RAS2Val19 mutant. Carbon 159-165 mitogen-activated protein kinase kinase PBS2 Saccharomyces cerevisiae S288C 97-101 1479360-2 1992 The gene is essential for manifestation of resistance to the antibiotic polymyxin B. Deletion of PBS2 enables a ras2-530 null mutant to grow on nonfermentable carbon sources; overexpression of PBS2+ enhances viability of a RAS2Val19 mutant. Carbon 159-165 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 112-116 23052877-6 2013 A suitable protocol for organic and elemental carbon separation was set up for the TGA/FTIR system and a comparison with the results obtained by the TOT method was carried out. Carbon 46-52 T-box transcription factor 1 Homo sapiens 83-86 1328482-2 1992 HCMV adsorbed to cells was neutralized by C-23 (complement-independent), but not by C-41 (complement-dependent). Carbon 1-2 nucleolin Homo sapiens 42-46 1328482-4 1992 The cell-to-cell infection of HCMV was also blocked only by C-23, and not by C-41. Carbon 31-32 nucleolin Homo sapiens 60-64 1324723-1 1992 Acetyl-CoA enol has been proposed as an intermediate in the citrate synthase (CS) reaction with Asp375 acting as a base, removing a proton from the methyl carbon of acetyl-CoA, and His274 acting as an acid, donating a proton to the carbonyl [Karpusas, M., Branchaud, B., & Remington, S.J. Carbon 155-161 citrate synthase Homo sapiens 60-76 1324723-1 1992 Acetyl-CoA enol has been proposed as an intermediate in the citrate synthase (CS) reaction with Asp375 acting as a base, removing a proton from the methyl carbon of acetyl-CoA, and His274 acting as an acid, donating a proton to the carbonyl [Karpusas, M., Branchaud, B., & Remington, S.J. Carbon 155-161 citrate synthase Homo sapiens 78-80 16669032-3 1992 Regulation of SPS by protein phosphorylation is important in vivo and may explain diurnal changes in SPS activity and carbon partitioning. Carbon 118-124 sucrose-phosphate synthase Zea mays 14-17 16669032-6 1992 There are apparent differences among species in the properties of SPS that may reflect different strategies for the control of carbon partitioning. Carbon 127-133 sucrose-phosphate synthase Zea mays 66-69 16669032-7 1992 The SPS gene has recently been cloned from maize; results of preliminary studies with transgenic tomato plants expressing high levels of maize SPS support the postulate that SPS activity can influence the partitioning of carbon between starch and sucrose. Carbon 221-227 sucrose-phosphate synthase Zea mays 4-7 16669032-7 1992 The SPS gene has recently been cloned from maize; results of preliminary studies with transgenic tomato plants expressing high levels of maize SPS support the postulate that SPS activity can influence the partitioning of carbon between starch and sucrose. Carbon 221-227 sucrose-phosphate synthase Zea mays 143-146 16669032-7 1992 The SPS gene has recently been cloned from maize; results of preliminary studies with transgenic tomato plants expressing high levels of maize SPS support the postulate that SPS activity can influence the partitioning of carbon between starch and sucrose. Carbon 221-227 sucrose-phosphate synthase Zea mays 143-146 1516101-3 1992 The replacement of hydroxyl groups by fluorine atoms occurred exclusively at C-6, as confirmed by carbon-13 NMR spectroscopy. Carbon 98-104 complement C6 Homo sapiens 77-80 1544898-5 1992 The levels of the mRNAs and proteins for both MRP20 and MRP49 were regulated in response to carbon source. Carbon 92-98 mitochondrial 54S ribosomal protein YmL41 Saccharomyces cerevisiae S288C 46-51 1631781-1 1992 Dihydrofolate reductase reduces folic acid to tetrahydrofolate as a prerequisite to one-carbon metabolism, which is required for normal embryonic de novo DNA synthesis. Carbon 88-94 dihydrofolate reductase Oryctolagus cuniculus 0-23 1740442-3 1992 We recently reported that GTP-binding proteins encoded by rab1B (GGCC), rab2 (GGCC), and rab5 (CCSN) are modified by 20-carbon isoprenyl derivatives of [3H]mevalonate when translated in vitro, despite having carboxyl-terminal sequences distinct from the Caa(M/S/L) motif. Carbon 120-126 RAB1B, member RAS oncogene family Homo sapiens 58-63 1664298-7 1991 We have also found that null alleles of certain STE genes (ste7, ste11 and ste12), known to affect cell-type specific gene expression and expression of some Ty-adjacent genes, have a clear effect on Ty-controlled ADH2 expression depending on the carbon source. Carbon 246-252 mitogen-activated protein kinase kinase kinase STE11 Saccharomyces cerevisiae S288C 65-70 1664298-7 1991 We have also found that null alleles of certain STE genes (ste7, ste11 and ste12), known to affect cell-type specific gene expression and expression of some Ty-adjacent genes, have a clear effect on Ty-controlled ADH2 expression depending on the carbon source. Carbon 246-252 homeodomain family transcription factor STE12 Saccharomyces cerevisiae S288C 75-80 1864360-1 1991 Studies on the osmotic induction of glycerol production and glycerol-3-phosphate dehydrogenase (NAD+) Production of glycerol and a key enzyme in glycerol production, glycerol 3-phosphate dehydrogenase (NAD+) (GPD), was studied in Saccharomyces cerevisiae cultured in basal media or media of high salinity, with glucose, raffinose or ethanol as the sole carbon source. Carbon 353-359 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 60-94 1993209-9 1991 We conclude that the presence of carbon at the 5-position of tetrahydrofolate analogues is sufficient for inhibition of GARFT, that N-8 and the 2-amino group are involved in binding of DDATHF to GARFT, probably through hydrogen bonds, and that the structures of the phenyl ring and amino acid side chain of DDATHF analogues are not primary determinants of GARFT inhibition by monoglutamate forms of these compounds. Carbon 33-39 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Homo sapiens 195-200 18597309-7 1991 Sixteen hours cultivation at 37 degrees C in a complex medium with lactose as inducer and carbon/energy source resulted in up to 30% of the volume and 48% of the total protein of biomass being accumulated for as prochymosin inclusion bodies. Carbon 90-96 chymosin Bos taurus 212-223 1986231-6 1991 Disruption of the MDH2 gene in a haploid strain also containing a disruption in the chromosomal MDH1 gene encoding the mitochondrial isozyme produced a strain unable to grow with acetate but capable of growth on rich medium with glycerol as a carbon source. Carbon 243-249 malate dehydrogenase MDH1 Saccharomyces cerevisiae S288C 96-100 2074532-4 1990 The amide carbonyl oxygen at 6-position is considered to coordinate with the reagent, because the largest downfield shifts were observed at the amide carbonyl carbon (C-6) in 13C-NMR and the amide hydrogen (H-7) in 1H-NMR. Carbon 10-16 complement C6 Homo sapiens 167-170 2165073-3 1990 The gene encoding AAC2 was also cloned and sequenced from an op1 revertant capable of growth on glycerol as a sole carbon source. Carbon 115-121 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 18-22 2162755-14 1990 Although Fru-2,6-P2 plays a key role in the regulation of carbon flux in the gluconeogenic pathway, the regulation of this flux depends on several factors and regulation of other key enzymes whose importance varies depending on the dietary and hormonal status of the animal. Carbon 58-64 zinc finger and BTB domain containing 22 Homo sapiens 9-12 2181283-7 1990 A greater reduction in REB1 activity is observed if the sin3 mutant strain is grown in media containing galactose as a carbon source. Carbon 119-125 transcriptional regulator SIN3 Saccharomyces cerevisiae S288C 56-60 33807231-1 2021 The SLC25A20 transporter, also known as carnitine acyl-carnitine carrier (CAC), catalyzes the transport of short, medium and long carbon chain acyl-carnitines across the mitochondrial inner membrane in exchange for carnitine. Carbon 130-136 solute carrier family 25 member 20 Homo sapiens 4-12 34953261-0 2022 MOF-derived N-doped ZnO carbon skeleton@hierarchical Bi2MoO6 S-scheme heterojunction for photodegradation of SMX: Mechanism, pathways and DFT calculation. Carbon 24-30 lysine acetyltransferase 8 Homo sapiens 0-3 34953459-2 2022 The crystal structure and chemical state of the Co and Ni oxyhydroxides which were precipitated on loofah-derived activated carbon (AC) using hypochlorite were characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), and BET surface area. Carbon 124-130 delta/notch like EGF repeat containing Homo sapiens 282-285 34656579-6 2022 The endogenous carbon sources from high-rate partial denitrification sludge contributed to low COD consumption in the process. Carbon 15-21 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 95-98 34715586-0 2022 Carbon nanotube field-effect transistor (CNT-FET)-based biosensor for rapid detection of SARS-CoV-2 (COVID-19) surface spike protein S1. Carbon 0-6 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 119-124 34619259-7 2022 The prepared turbostratic carbon, when used as lithium anode, renders excellent electrochemical performances with reversible specific capacity of 350 mAhg-1 (at 300 mAg-1) with 81% capacity retention after 500 cycles. Carbon 26-32 dentin matrix protein 1 Mus musculus 165-170 1648777-1 1991 The periplasmic acid glucose-1-phosphatase (G-1-Pase) encoded by gene agp is necessary for the growth of Escherichia coli in a minimal medium containing glucose-1-phosphate (G-1-P) as the sole source of carbon. Carbon 203-209 glucose-1-phosphatase precursor Escherichia coli 70-73 1648777-2 1991 From a mutant in which the agp gene was inactivated, suppressors were isolated which recovered the ability to utilize G-1-P as carbon source. Carbon 127-133 glucose-1-phosphatase precursor Escherichia coli 27-30 1648777-7 1991 This phosphate-starvation-induced bypass of G-1-Pase by UhpT + Pgm systems shows that agp is essential for G-1-P assimilation as a carbon source only in a high-phosphate medium, a result in agreement with the lack of agp regulation by inorganic phosphate. Carbon 131-137 glucose-1-phosphatase precursor Escherichia coli 86-89 2133086-8 1990 Consideration of structure/activity relationships among the 17 alpha-acetylenic steroids examined indicates that the delta 15 double bond is critical but is not in itself sufficient for the inactivation process, which is postulated to result from attack of P-450 on the substituted acetylenic carbon and lead to porphyrin N-alkylation. Carbon 293-299 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 257-262 1970569-12 1990 By measuring the levels of ACH1 mRNA and acetyl-CoA hydrolase activity in different growth phases and by examining the effects of various carbon sources, we have demonstrated that ACH1 expression is repressed by glucose. Carbon 138-144 acetyl-CoA hydrolase Saccharomyces cerevisiae S288C 180-184 2189786-5 1990 A disruption of the POX1 coding sequence diminishes the ability of yeast cells to grow on oleic acid as a sole carbon source. Carbon 111-117 acyl-CoA oxidase Saccharomyces cerevisiae S288C 20-24 2192389-4 1990 Fat contains a high concentration of carbon. Carbon 37-43 FAT atypical cadherin 1 Homo sapiens 0-3 2192389-5 1990 Carbon in fat can be estimated and from this the total body fat can be calculated. Carbon 0-6 FAT atypical cadherin 1 Homo sapiens 10-13 2192389-5 1990 Carbon in fat can be estimated and from this the total body fat can be calculated. Carbon 0-6 FAT atypical cadherin 1 Homo sapiens 60-63 33800410-7 2021 Finally, a symmetric carbon/carbon supercapacitor fabricated with such CCNF as electrode delivered an energy density of 21.1 Wh/kg at the power density of 0.6 kW/kg, which is comparable to commercial active carbon supercapacitors. Carbon 21-27 cyclin F Homo sapiens 71-75 33800410-7 2021 Finally, a symmetric carbon/carbon supercapacitor fabricated with such CCNF as electrode delivered an energy density of 21.1 Wh/kg at the power density of 0.6 kW/kg, which is comparable to commercial active carbon supercapacitors. Carbon 28-34 cyclin F Homo sapiens 71-75 33800410-7 2021 Finally, a symmetric carbon/carbon supercapacitor fabricated with such CCNF as electrode delivered an energy density of 21.1 Wh/kg at the power density of 0.6 kW/kg, which is comparable to commercial active carbon supercapacitors. Carbon 28-34 cyclin F Homo sapiens 71-75 32797897-2 2020 In this work, a novel glucose-based nitrogen-doped carbon dots (Glc-NCDs)-bonded silica stationary phase (Sil-Glc-NCDs) was synthesized and characterized carefully. Carbon 51-57 STIL centriolar assembly protein Homo sapiens 106-109 18336638-10 2008 RESULTS: Alcohols with increasing carbon chain length exhibited a variable effect on the ratio of acetylated lys9 histone H3 to beta-actin. Carbon 34-40 actin, beta Rattus norvegicus 128-138 34717949-4 2022 Owing to the improved selectivity of ZnO, excellent conductivity of carbon fiber, promoted active site exposure and mass transfer of hollow structure, the free-standing membrane electrode shows superior 2e-WOR performances with high selectivity (83.8% at 2.8 V vs. RHE), H2O2 generation rate (19.7 mumol cm-2 min-1) and robust stability. Carbon 68-74 factor interacting with PAPOLA and CPSF1 Homo sapiens 265-268 34863540-0 2022 RGO/Manganese Silicate/MOF-derived carbon Double-Sandwich-Like structure as the cathode material for aqueous rechargeable Zn-ion batteries. Carbon 35-41 lysine acetyltransferase 8 Homo sapiens 23-26 34863540-3 2022 Herein, we successfully construct a double-sandwich-like structure, MOF-derived carbon/manganese silicate/reduced graphene oxide/manganese silicate/MOF-derived carbon (denoted as rGO/MnSi/MOF-C), as the cathode material for ARZIBs. Carbon 80-86 lysine acetyltransferase 8 Homo sapiens 68-71 34863540-3 2022 Herein, we successfully construct a double-sandwich-like structure, MOF-derived carbon/manganese silicate/reduced graphene oxide/manganese silicate/MOF-derived carbon (denoted as rGO/MnSi/MOF-C), as the cathode material for ARZIBs. Carbon 80-86 lysine acetyltransferase 8 Homo sapiens 148-151 34863540-3 2022 Herein, we successfully construct a double-sandwich-like structure, MOF-derived carbon/manganese silicate/reduced graphene oxide/manganese silicate/MOF-derived carbon (denoted as rGO/MnSi/MOF-C), as the cathode material for ARZIBs. Carbon 80-86 lysine acetyltransferase 8 Homo sapiens 188-191 34863540-3 2022 Herein, we successfully construct a double-sandwich-like structure, MOF-derived carbon/manganese silicate/reduced graphene oxide/manganese silicate/MOF-derived carbon (denoted as rGO/MnSi/MOF-C), as the cathode material for ARZIBs. Carbon 160-166 lysine acetyltransferase 8 Homo sapiens 68-71 34863540-3 2022 Herein, we successfully construct a double-sandwich-like structure, MOF-derived carbon/manganese silicate/reduced graphene oxide/manganese silicate/MOF-derived carbon (denoted as rGO/MnSi/MOF-C), as the cathode material for ARZIBs. Carbon 160-166 lysine acetyltransferase 8 Homo sapiens 148-151 34863540-3 2022 Herein, we successfully construct a double-sandwich-like structure, MOF-derived carbon/manganese silicate/reduced graphene oxide/manganese silicate/MOF-derived carbon (denoted as rGO/MnSi/MOF-C), as the cathode material for ARZIBs. Carbon 160-166 lysine acetyltransferase 8 Homo sapiens 188-191 34863540-4 2022 Among the double-sandwich-like structure, manganese silicate (Mn2SiO4, denoted as MnSi) is in the middle of internal reduced graphene oxide (rGO) and external MOF-8 derived carbon (MOF-C). Carbon 173-179 lysine acetyltransferase 8 Homo sapiens 181-184 34803225-0 2022 Corrigendum to "Cobalt metal-organic framework modified carbon cloth/paper hybrid electrochemical button-sensor for nonenzymatic glucose diagnostics" (Sens. Carbon 56-62 potassium channel tetramerization domain containing 1 Homo sapiens 151-155 23487916-2 2013 The surface structures of tested carbons were observed and analyzed by SEM and BET methods. Carbon 33-40 delta/notch like EGF repeat containing Homo sapiens 79-82 34656853-0 2022 A sandwiched photoelectrochemical biosensing platform for detecting Cytokeratin-19 fragments based on Ag2S-sensitized BiOI/Bi2S3 heterostructure amplified by sulfur and nitrogen co-doped carbon quantum dots. Carbon 187-193 keratin 19 Homo sapiens 68-82 34788502-4 2022 For this, a well-designed synthetic route combining wet impregnation with a two-step thermal treatment process was established to construct PtSn/SnO x interfaces on carbon nanotubes. Carbon 165-171 strawberry notch homolog 1 Homo sapiens 145-148 34740669-7 2022 However, the total amount of carbon fixed into compost in AD-15 was 6.6% higher than that in AD-21. Carbon 29-35 AD15 Homo sapiens 58-63 34794809-2 2022 Herein, Co9S8 loaded with S, N co-doped carbon core-shell catalyst (Co9S8@SNC) was reasonably designed and synthesized by using the strong coordination effect between Co2+ and CS at the molecular level. Carbon 40-46 citrate synthase Homo sapiens 176-178 23083520-1 2012 Selective generation of an amine-terminated self-assembled monolayer bound to silicon wafers via a silicon-carbon linkage was realized by photocatalytically reducing the corresponding azide-terminated, self-assembled monolayers (Az-SAMs). Carbon 107-113 methionine adenosyltransferase 1A Homo sapiens 232-236 34189693-5 2022 Referring to the experimental findings, the prepared activated carbons have BET surface area of >1000 m2 g-1, which implies the effectiveness of the single-stage H3PO4 activation. Carbon 63-70 delta/notch like EGF repeat containing Homo sapiens 76-79 34189693-6 2022 Furthermore, the prepared activated carbon via 50 wt.% H3PO4 activation shows the highest BET surface area and carbon dioxide (CO2) adsorption capacity of 1.45 mmol g-1 at 25 C/1 bar and 9.0 mmol g-1 at 25 C/30 bar. Carbon 36-42 delta/notch like EGF repeat containing Homo sapiens 90-93 34487927-1 2022 The nitrogen-doped carbon (NC) coating encapsulating heterostructural Sn/SnO2 microcube powders (Sn/SnO2@NC) are successfully fabricated through hydrothermal, polymerization of hydrogel, and carbonization processes, in which the SnO precursor powders exhibit regular microcube structure and uniform size distribution in the presence of optimized N2H4 H2O (3.0 mL of 1.0 mol/L). Carbon 19-25 strawberry notch homolog 1 Homo sapiens 100-103 34487927-1 2022 The nitrogen-doped carbon (NC) coating encapsulating heterostructural Sn/SnO2 microcube powders (Sn/SnO2@NC) are successfully fabricated through hydrothermal, polymerization of hydrogel, and carbonization processes, in which the SnO precursor powders exhibit regular microcube structure and uniform size distribution in the presence of optimized N2H4 H2O (3.0 mL of 1.0 mol/L). Carbon 19-25 strawberry notch homolog 1 Homo sapiens 229-232 23066947-4 2012 We observe an enhanced absorption in the carbon nanotube optical resonances, and an external quantum efficiency of 12.3% and 8.7% was deduced for the E11 and E22 transitions, respectively. Carbon 41-47 transcription factor 4 Homo sapiens 158-161 34958195-4 2022 Hence, SnS2 nanosheets with different sizes are loaded on the surface of carbon paper (SnS2@CP) to improve the potassiophilicity and realize dendrite-free K-metal anodes. Carbon 73-79 sodium voltage-gated channel alpha subunit 11 Homo sapiens 7-11 34741650-3 2022 In our study, we developed an electrochemical biosensing platform based on gold clusters, mercaptoethanol, the spike protein of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antigen and bovine serum albumin-modified glassy carbon electrode able to detect the SARS-CoV-2 spike antibody. Carbon 238-244 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 285-290 34487754-4 2022 Dietary delivery of 13C6-glucose to these mice, followed by deep network metabolic tracing, revealed that low rates of PFK1 activity promote selective routing of glucose-derived carbon to the purine synthesis pathway to form 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR). Carbon 178-184 phosphofructokinase, liver, B-type Mus musculus 119-123 34487754-6 2022 We also observed that PFK1 influenced glucose-derived carbon deposition in glycogen, but did not affect hexosamine biosynthetic pathway activity. Carbon 54-60 phosphofructokinase, liver, B-type Mus musculus 22-26 34215486-6 2022 The application of strategies such as codigestion of PRBs with carbon-rich biomass and microbial stimulation/augmentation would make PRB biomethanation more feasible. Carbon 63-69 RB transcriptional corepressor 1 Homo sapiens 133-136 23421201-2 2012 A number of nanomaterials, including carbon based nanomaterials (Gd@C82(OH)22)n, C60(OH)22 and C60(C(COOH)2)2 etc., exhibit a very high antineoplastic efficiency and show almost no toxicity in vivo and in vitro. Carbon 37-43 complement C8 beta chain Homo sapiens 68-77 34893905-5 2022 BLZ8 regulated the expression of genes likely involved in the carbon-concentrating mechanism (CCM): HIGH-LIGHT ACTIVATED 3 (HLA3), CARBONIC ANHYDRASE 7 (CAH7), and CARBONIC ANHYDRASE 8 (CAH8). Carbon 62-68 uncharacterized protein Chlamydomonas reinhardtii 164-184 34893905-5 2022 BLZ8 regulated the expression of genes likely involved in the carbon-concentrating mechanism (CCM): HIGH-LIGHT ACTIVATED 3 (HLA3), CARBONIC ANHYDRASE 7 (CAH7), and CARBONIC ANHYDRASE 8 (CAH8). Carbon 62-68 uncharacterized protein Chlamydomonas reinhardtii 186-190 34417700-0 2022 Green synthesis of zinc oxide nanoparticles loaded on activated carbon prepared from walnut peel extract for the removal of Eosin Y and Erythrosine B dyes from aqueous solution: experimental approaches, kinetics models, and thermodynamic studies. Carbon 64-70 estrogen receptor 2 Homo sapiens 136-149 34417700-2 2022 The present study investigate the green synthesis of zinc oxide nanoparticles (ZnO-NPs) doped on activated carbon (AC) prepared from walnut peel extract and to estimate its efficiency in the removal of Eosin Y (Eo-Y) and Erythrosine B (Er-B) from its aqueous solution. Carbon 107-113 estrogen receptor 2 Homo sapiens 221-234 34417700-2 2022 The present study investigate the green synthesis of zinc oxide nanoparticles (ZnO-NPs) doped on activated carbon (AC) prepared from walnut peel extract and to estimate its efficiency in the removal of Eosin Y (Eo-Y) and Erythrosine B (Er-B) from its aqueous solution. Carbon 107-113 estrogen receptor 2 Homo sapiens 236-240 34417700-2 2022 The present study investigate the green synthesis of zinc oxide nanoparticles (ZnO-NPs) doped on activated carbon (AC) prepared from walnut peel extract and to estimate its efficiency in the removal of Eosin Y (Eo-Y) and Erythrosine B (Er-B) from its aqueous solution. Carbon 115-117 estrogen receptor 2 Homo sapiens 221-234 34417700-2 2022 The present study investigate the green synthesis of zinc oxide nanoparticles (ZnO-NPs) doped on activated carbon (AC) prepared from walnut peel extract and to estimate its efficiency in the removal of Eosin Y (Eo-Y) and Erythrosine B (Er-B) from its aqueous solution. Carbon 115-117 estrogen receptor 2 Homo sapiens 236-240 26704072-3 2012 PN-ACNT arrays were shown to exhibit a high ORR electrocatalytic activity, superb long-term durability, and good tolerance to methanol and carbon monoxide, significantly outperforming their counterparts doped with P (P-ACNT) or N (N-ACNT) only and even comparable to the commercially available Pt-C catalyst (45 wt % Pt on Vulcan XC-72R; E-TEK) due to a demonstrated synergetic effect arising from the co-doping of CNTs with both P and N. Carbon 4-5 TEK receptor tyrosine kinase Homo sapiens 340-343 34887407-2 2021 We present a direct comparison of the contribution of krill and salp faecal pellets (FP) to vertical carbon flux at the Antarctic Peninsula using a combination of sediment traps, FP production, carbon content, microbial degradation, and krill and salp abundances. Carbon 101-107 KH RNA binding domain containing, signal transduction associated 3 Homo sapiens 64-68 22738231-8 2012 Lro1p acylates NBD-ceramide by attaching a fatty acid to the hydroxy group on the first carbon atom of the long-chain base. Carbon 88-94 phospholipid:diacylglycerol acyltransferase Saccharomyces cerevisiae S288C 0-5 34605141-0 2021 Interfacial Super-Assembly of Ordered Mesoporous Carbon-Silica/AAO Hybrid Membrane with Enhanced Permselectivity for Temperature- and pH-Regulated Smart Ion Transport. Carbon 49-55 phenylalanine hydroxylase Homo sapiens 134-136 34605141-4 2021 Here, we fabricate a new mesoporous carbon-silica/anodized aluminum (MCS/AAO) nanofluidic device with enhanced permselectivity for temperature- and pH-regulated energy generation. Carbon 36-42 phenylalanine hydroxylase Homo sapiens 148-150 34866245-2 2021 Herein, a facile strategy has been employed to successfully synthesize the porous Cox P hierarchical nanostructures supported on flexible carbon fiber cloth (Cox P@CFC), constructing a robust architecture of ordered nanoarrays. Carbon 138-144 cytochrome c oxidase subunit 8A Homo sapiens 158-161 34893855-10 2022 Prenatal Poly I:C exposure decreased expression of GABAA receptor subunits Gabrb3 in the PFC, and Gabrb1 and dopamine D2 (Drd2) in the hippocampus, but increased NMDA receptor subunit Grin2a in the PFC, 5-HT2A in the hippocampus, and Gabrb3 and Drd2 in the NAc. Carbon 16-17 dopamine receptor D2 Rattus norvegicus 245-249 22527117-4 2012 Total PAH concentrations in indoor dust samples showed a better correlation to black carbon compared to total organic carbon contents. Carbon 85-91 phenylalanine hydroxylase Homo sapiens 6-9 34658075-0 2021 Electron and Ion Co-Conductive Catalyst Achieving Instant Transformation of Lithium Polysulfide towards Li2 S. Most of the catalysts in lithium sulfur (Li-S) batteries present low electronic conductivity and the lithium polysulfides (LiPSs) must diffuse onto the surface of the carbon materials to achieve their conversion reaction. Carbon 278-284 ATP binding cassette subfamily A member 12 Homo sapiens 104-107 34658075-2 2021 Herein, a unique electron and ion co-conductive catalyst of carbon-coated Li1.4 Al0.4 Ti1.6 (PO4 )3 (C@LATP) is developed, which not only possesses strong adsorption to LiPSs, but, more importantly, also promotes the instantaneous conversion reaction of LiPSs to Li2 S. The C@LATP nanoparticles as catalytic active sites can synchronously and efficiently provide both Li ions and electrons to facilitate the conversion reaction of LiPSs. Carbon 60-66 transglutaminase 1 Homo sapiens 74-77 22527117-4 2012 Total PAH concentrations in indoor dust samples showed a better correlation to black carbon compared to total organic carbon contents. Carbon 118-124 phenylalanine hydroxylase Homo sapiens 6-9 34658075-2 2021 Herein, a unique electron and ion co-conductive catalyst of carbon-coated Li1.4 Al0.4 Ti1.6 (PO4 )3 (C@LATP) is developed, which not only possesses strong adsorption to LiPSs, but, more importantly, also promotes the instantaneous conversion reaction of LiPSs to Li2 S. The C@LATP nanoparticles as catalytic active sites can synchronously and efficiently provide both Li ions and electrons to facilitate the conversion reaction of LiPSs. Carbon 60-66 ATP binding cassette subfamily A member 12 Homo sapiens 263-266 22914602-9 2012 RESULTS: Long-acting beta2 agonists significantly down-regulated the poly I:C-induced IP-10 protein and messenger RNA expression in BEAS-2B cells. Carbon 76-77 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 21-26 34537288-3 2021 The HPr kinase/phosphorylase (HPrK/P), involved in the use of carbon sources in Gram-positive, phopshorylates HPr at a serine. Carbon 62-68 haptoglobin-related protein Homo sapiens 4-7 34537288-3 2021 The HPr kinase/phosphorylase (HPrK/P), involved in the use of carbon sources in Gram-positive, phopshorylates HPr at a serine. Carbon 62-68 haptoglobin-related protein Homo sapiens 110-113 34822896-0 2022 Adsorption mechanism of a new combined collector (PS-1) on unburned carbon in gasification slag. Carbon 68-74 presenilin 1 Homo sapiens 50-54 22914602-13 2012 CONCLUSION: Long-acting beta2 agonists down-regulate poly I:C-induced IP-10 expression in BEAS-2B cells via the beta2 adrenoreceptor-cyclic adenosine monophosphate and c-Jun N-terminal kinase/c-Jun pathways. Carbon 0-1 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 24-29 22914602-13 2012 CONCLUSION: Long-acting beta2 agonists down-regulate poly I:C-induced IP-10 expression in BEAS-2B cells via the beta2 adrenoreceptor-cyclic adenosine monophosphate and c-Jun N-terminal kinase/c-Jun pathways. Carbon 0-1 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 112-117 22967613-0 2012 Enzyme biosensor for androsterone based on 3alpha-hydroxysteroid dehydrogenase immobilized onto a carbon nanotubes/ionic liquid/NAD+ composite electrode. Carbon 98-104 aldo-keto reductase family 1 member C3 Homo sapiens 43-78 34822896-3 2022 This study applies PS-1 (a mixture of kerosene and oleic acid at the ratio of 7:3) to improve the flotation separation effect of carbon from CGFS. Carbon 129-135 presenilin 1 Homo sapiens 19-23 34831878-2 2021 We examined the cumulative short-term effect of black carbon (BC) exposure on systolic (SBP) and diastolic (DBP) BP and assessed effect modification by participant characteristics. Carbon 54-60 selenium binding protein 1 Homo sapiens 88-91 22967613-1 2012 A 3alpha-hydrosteroid biosensor for androsterone determination has been prepared by immobilizing the enzyme 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) in a composite electrode platform constituted of a mixture of multi-walled carbon nanotubes (MWCNTs), octylpyridinium hexafluorophosphate (OPPF(6)) ionic liquid and NAD(+) cofactor. Carbon 232-238 aldo-keto reductase family 1 member C3 Homo sapiens 108-143 22967613-1 2012 A 3alpha-hydrosteroid biosensor for androsterone determination has been prepared by immobilizing the enzyme 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) in a composite electrode platform constituted of a mixture of multi-walled carbon nanotubes (MWCNTs), octylpyridinium hexafluorophosphate (OPPF(6)) ionic liquid and NAD(+) cofactor. Carbon 232-238 aldo-keto reductase family 1 member C3 Homo sapiens 145-155 22659048-5 2012 Here we show that expression of GPX1 was induced in medium containing oleic acid as a carbon source in an Msn2/Msn4-dependent manner. Carbon 86-92 glutathione peroxidase GPX1 Saccharomyces cerevisiae S288C 32-36 34780089-2 2022 Here, we utilize naturally occurring carbon isotope ratios (13 C/12 C; delta13 C) to uncover the origin of brain PAM. Carbon 37-43 peptidylglycine alpha-amidating monooxygenase Mus musculus 113-116 22769428-5 2012 Compared with N-doped carbon, B,N-doped or P,N-doped carbon shows 1.2 or 2.1 times higher ORR activity at 0.6 V (vs RHE) in acidic media. Carbon 53-59 factor interacting with PAPOLA and CPSF1 Homo sapiens 116-119 34698489-5 2021 Our nanosensor constructs consist of poly(ethylene glycol) (PEG)-phospholipid heteropolymers adsorbed onto near-infrared (nIR) fluorescent single-walled carbon nanotubes (SWCNTs) that recognize the nucleocapsid (N) and spike (S) protein of SARS-CoV-2 using unique three-dimensional (3D) nanosensor interfaces. Carbon 153-159 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 198-224 34698489-5 2021 Our nanosensor constructs consist of poly(ethylene glycol) (PEG)-phospholipid heteropolymers adsorbed onto near-infrared (nIR) fluorescent single-walled carbon nanotubes (SWCNTs) that recognize the nucleocapsid (N) and spike (S) protein of SARS-CoV-2 using unique three-dimensional (3D) nanosensor interfaces. Carbon 153-159 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 226-227 22769428-6 2012 The most active catalyst in the reaction is the ternary-doped carbon (B,P,N-doped carbon), which records -6.0 mA/mg of mass activity at 0.6 V (vs RHE), and it is 2.3 times higher than that of the N-doped carbon. Carbon 62-68 factor interacting with PAPOLA and CPSF1 Homo sapiens 146-149 22769428-6 2012 The most active catalyst in the reaction is the ternary-doped carbon (B,P,N-doped carbon), which records -6.0 mA/mg of mass activity at 0.6 V (vs RHE), and it is 2.3 times higher than that of the N-doped carbon. Carbon 82-88 factor interacting with PAPOLA and CPSF1 Homo sapiens 146-149 22769428-6 2012 The most active catalyst in the reaction is the ternary-doped carbon (B,P,N-doped carbon), which records -6.0 mA/mg of mass activity at 0.6 V (vs RHE), and it is 2.3 times higher than that of the N-doped carbon. Carbon 82-88 factor interacting with PAPOLA and CPSF1 Homo sapiens 146-149 34742186-1 2021 The electronic spectrum of methyl vinyl ketone oxide (MVK-oxide), a four-carbon Criegee intermediate derived from isoprene ozonolysis, is examined on its second pi* pi transition, involving primarily the vinyl group, at UV wavelengths (lambda) below 300 nm. Carbon 73-79 mevalonate kinase Homo sapiens 54-57 22637474-9 2012 Overall, these findings implicate Arg-120 and hydrophobic groove residues as determinants that govern proper alignment of the bisallylic carbon below Tyr-385 for catalysis in COX-2 and confirm nuances between COX isoforms that explain substrate promiscuity. Carbon 137-143 cytochrome c oxidase II, mitochondrial Mus musculus 175-180 34147984-1 2021 Denitrification in electroactive constructed wetland (EW) systems is constrained by the carbon source and the carbon/nitrogen (C/N) ratio (the COD/TN ratio). Carbon 110-116 C-type lectin domain family 3 member B Homo sapiens 147-149 34147984-1 2021 Denitrification in electroactive constructed wetland (EW) systems is constrained by the carbon source and the carbon/nitrogen (C/N) ratio (the COD/TN ratio). Carbon 127-128 C-type lectin domain family 3 member B Homo sapiens 147-149 22663136-3 2012 The present analysis considers a range of assumed differential ESP collection efficiencies for powdered activated carbon as compared to fly ash. Carbon 114-120 Epidermal stripes and patches Drosophila melanogaster 63-66 34585828-1 2021 The Ni-rich LiNi0.8 Co0.10 Mn0.1 O2 (NCM811) cathode coated by combining with multi-walled carbon nanotubes (MWCNTs) and polyimide (PI) produces a PI3-NCM811 cathode, which markedly improves cycling stability and suppresses secondary crystal cracking. Carbon 91-97 peptidase inhibitor 3 Homo sapiens 147-150 34287077-5 2021 Our results showed that when U87- or TLR3-transfected HEK293-TLR7 cells were stimulated with TLR-ligands, such as poly I:C plus LPS or poly I:C plus R837, IFN-beta production was significantly increased with MyD88 inhibition in a dose-dependent manner. Carbon 142-143 toll like receptor 3 Homo sapiens 37-41 34287077-5 2021 Our results showed that when U87- or TLR3-transfected HEK293-TLR7 cells were stimulated with TLR-ligands, such as poly I:C plus LPS or poly I:C plus R837, IFN-beta production was significantly increased with MyD88 inhibition in a dose-dependent manner. Carbon 142-143 MYD88 innate immune signal transduction adaptor Homo sapiens 208-213 22679919-5 2012 This increase of CO(2) adsorption capacity after chemical activation was due to an increase of BET surface area and pore volume in all carbon materials. Carbon 135-141 delta/notch like EGF repeat containing Homo sapiens 95-98 34628853-3 2021 Here, uniform SnS2 nanosheets are coated on the carbon paper (SnS2@CP) skeleton and then transformed into a mixed layer of Li2S/Li-Sn after lithiation. Carbon 48-54 sodium voltage-gated channel alpha subunit 11 Homo sapiens 14-18 22966719-1 2012 The aim of this study was to evaluate the ability of electron beam irradiation to drive stabilization reactions within PAN nanofiber mats to obtain carbon nanofiber mats. Carbon 148-154 adenosine deaminase 2 Homo sapiens 119-122 34675266-8 2021 Second, compared with TP, EP can improve bulk density (BD), soil organic carbon (SOC), total nitrogen (TN) and cation exchange capacity (CEC), Finally, the chemical weathering intensity differed among NE, TP and EP and followed the order of TP > NE > EP. Carbon 73-79 epiregulin Homo sapiens 26-28 34675266-8 2021 Second, compared with TP, EP can improve bulk density (BD), soil organic carbon (SOC), total nitrogen (TN) and cation exchange capacity (CEC), Finally, the chemical weathering intensity differed among NE, TP and EP and followed the order of TP > NE > EP. Carbon 73-79 epiregulin Homo sapiens 212-214 34587602-0 2021 SnS2 nanosheet arrays anchoring on functionalized carbon cloth for quasi-solid-state flexible supercapacitor with satisfactory electrochemical performance and mechanical stability. Carbon 50-56 sodium voltage-gated channel alpha subunit 11 Homo sapiens 0-4 22966719-4 2012 Using the irradiation-stabilized PAN nanofiber mats, carbon nanofibers were obtained by pyrolysis in a tube furnace for 1 h at 1,000 degrees C under an N2 atmosphere. Carbon 53-59 adenosine deaminase 2 Homo sapiens 33-36 22754872-3 2012 It is known that ACH1 inactivation results in growth defects on media containing acetate as a sole carbon and energy source which are particularly severe at low pH. Carbon 99-105 acetyl-CoA hydrolase Saccharomyces cerevisiae S288C 17-21 34643794-5 2022 Pro-inflammatory signaling was induced by TLR-3 agonist polyinosinic:polycytidylic acid (Poly I:C). Carbon 96-97 toll like receptor 3 Homo sapiens 42-47 22581462-0 2012 [Cu(dap)2Cl] as an efficient visible-light-driven photoredox catalyst in carbon-carbon bond-forming reactions. Carbon 73-79 death associated protein Homo sapiens 4-7 34681679-3 2021 Previously, we reported that oropharyngeal instillation of multiwall carbon nanotubes (MWCNT) into C57Bl/6 mice induced sarcoid-like granulomas and upregulation of MMP12. Carbon 69-75 matrix metallopeptidase 12 Mus musculus 164-169 34607986-2 2021 The PR3 groups avoid being eclipsed with the C-Cl bonds. Carbon 45-46 proteinase 3 Homo sapiens 4-7 34705314-3 2021 Hence, the electron-rich silyl-substituted complex undergoes cyclometallation or shift of the imine moiety after cooperative activation of the P-H bond across the M=C linkage, depending on the electronics of the applied phosphine. Carbon 165-166 phenylalanine hydroxylase Homo sapiens 143-146 34866245-2 2021 Herein, a facile strategy has been employed to successfully synthesize the porous Cox P hierarchical nanostructures supported on flexible carbon fiber cloth (Cox P@CFC), constructing a robust architecture of ordered nanoarrays. Carbon 138-144 cytochrome c oxidase subunit 8A Homo sapiens 82-85 34893855-10 2022 Prenatal Poly I:C exposure decreased expression of GABAA receptor subunits Gabrb3 in the PFC, and Gabrb1 and dopamine D2 (Drd2) in the hippocampus, but increased NMDA receptor subunit Grin2a in the PFC, 5-HT2A in the hippocampus, and Gabrb3 and Drd2 in the NAc. Carbon 16-17 dopamine receptor D2 Rattus norvegicus 122-126 22581462-0 2012 [Cu(dap)2Cl] as an efficient visible-light-driven photoredox catalyst in carbon-carbon bond-forming reactions. Carbon 80-86 death associated protein Homo sapiens 4-7 22516955-1 2012 Polyinosinic-polycytidylic acid (poly I:C), a TLR3 ligand, is currently being tested in human clinical trials as an adjuvant to anti-cancer vaccines and in combination with other therapies. Carbon 40-41 toll like receptor 3 Homo sapiens 46-50 34186386-2 2021 To tackle these challenges, the amorphous CoP anchored on N-doped carbon nanospheres with hollow porous structures (CoP/HCS) has been synthesized as a superior sulfur host via a facial pyrolysis approach. Carbon 66-72 holocarboxylase synthetase Homo sapiens 120-123 34186386-5 2021 More importantly, the synergistic incorporation of CoP and HCS improved the inherit low conductivity by anchoring on the N-doped carbon hollow, thus leading to excellent performance for Li-S batteries. Carbon 129-135 holocarboxylase synthetase Homo sapiens 59-62 34425027-7 2021 As a representative example, Li2 S is in situ implanted into a hierarchical porous cross-linked puffed carbon (CPC) matrix to verify its application in lithium-sulfur batteries. Carbon 103-109 ATP binding cassette subfamily A member 12 Homo sapiens 29-32 22481162-0 2012 The Arabidopsis ubiquitin ligases ATL31 and ATL6 control the defense response as well as the carbon/nitrogen response. Carbon 93-99 carbon/nitrogen insensitive 1 Arabidopsis thaliana 34-39 34650922-0 2021 Dosimetric Impact of Inter-Fraction Anatomical Changes in Carbon Ion Boost Treatment for High-Risk Prostate Cancer (AIRC IG 14300). Carbon 58-64 phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase Homo sapiens 116-120 34695651-5 2021 PU.1 expression also primes the cells to develop a strong immune response against the dsRNA virus mimic polyinosinic:polycytidylic acid (poly I:C) by significantly up-regulating Interferon-beta (14.9 fold change with p-value <0.0001). Carbon 144-145 interferon beta 1 Homo sapiens 178-193 34850511-6 2022 Our results also reveal that only two carbon atoms of the spacer between thiol and amino on CS are very critical to the excellent etching ability. Carbon 38-44 citrate synthase Homo sapiens 92-94 22539451-6 2012 It also demonstrates eta(5)- or eta(6)-binding of metals to the curved carbon surface of 1(2-), depending on the crystallization conditions. Carbon 71-77 endothelin receptor type A Homo sapiens 21-24 34883640-0 2021 Ionic EAP Actuators with Electrodes Based on Carbon Nanomaterials. Carbon 45-51 glutamyl aminopeptidase Homo sapiens 6-9 34685810-5 2021 The process of carbon sequestration (CS) involves transferring CO2 from the atmosphere into the soil or storage of other forms of carbon to either defer or mitigate global warming and avoid dangerous climate change. Carbon 15-21 citrate synthase Homo sapiens 37-39 34685810-5 2021 The process of carbon sequestration (CS) involves transferring CO2 from the atmosphere into the soil or storage of other forms of carbon to either defer or mitigate global warming and avoid dangerous climate change. Carbon 130-136 citrate synthase Homo sapiens 37-39 34544338-0 2021 Carbon nanoparticles in Mongolian medicine alleviate acute gastric ulcer induced by ethanol through regulating Fas/FasL pathway. Carbon 0-6 Fas ligand (TNF superfamily, member 6) Mus musculus 115-119 34896810-2 2021 The production of biologically stable drinking water is challenging for conventional surface water treatment plants using reservoirs as feed water due to the presence of slowly biodegradable particulate and high-molecular weight biopolymeric organic carbon (high-MW OC) which increases the Microbial Growth Potential (MGP) in the feed water and produced drinking water. Carbon 250-256 matrix Gla protein Homo sapiens 290-316 22539451-6 2012 It also demonstrates eta(5)- or eta(6)-binding of metals to the curved carbon surface of 1(2-), depending on the crystallization conditions. Carbon 71-77 endothelin receptor type A Homo sapiens 32-35 34896810-2 2021 The production of biologically stable drinking water is challenging for conventional surface water treatment plants using reservoirs as feed water due to the presence of slowly biodegradable particulate and high-molecular weight biopolymeric organic carbon (high-MW OC) which increases the Microbial Growth Potential (MGP) in the feed water and produced drinking water. Carbon 250-256 matrix Gla protein Homo sapiens 318-321 34280615-0 2021 Pan2-Pan3 complex, together with Ccr4-Not complex, has a role in the cell growth on non-fermentable carbon sources. Carbon 100-106 CCR4-NOT core exoribonuclease subunit CCR4 Saccharomyces cerevisiae S288C 33-37 34280615-5 2021 Ccr4, Pan2, and Pan3 were phosphorylated in GlyLac medium, suggesting that the activities of Ccr4, Pan2, and Pan3 may be regulated by phosphorylation in response to change of carbon sources. Carbon 175-181 CCR4-NOT core exoribonuclease subunit CCR4 Saccharomyces cerevisiae S288C 0-4 34280615-5 2021 Ccr4, Pan2, and Pan3 were phosphorylated in GlyLac medium, suggesting that the activities of Ccr4, Pan2, and Pan3 may be regulated by phosphorylation in response to change of carbon sources. Carbon 175-181 CCR4-NOT core exoribonuclease subunit CCR4 Saccharomyces cerevisiae S288C 93-97 34280615-7 2021 Our results suggest that the Pan2-Pan3 complex, together with the Ccr4-Not complex, has important roles in the growth on non-fermentable carbon sources. Carbon 137-143 CCR4-NOT core exoribonuclease subunit CCR4 Saccharomyces cerevisiae S288C 66-70 22596163-4 2012 Here we report the crystal structure of human NOP, solved in complex with the peptide mimetic antagonist compound-24 (C-24) (ref. Carbon 118-119 opioid related nociceptin receptor 1 Homo sapiens 46-49 34751881-8 2022 Carbon emission trading policy had a significant positive effect on improving EE overall. Carbon 0-6 3-hydroxyanthranilate 3,4-dioxygenase Homo sapiens 31-34 34751881-9 2022 In particular, green technology innovation and energy structure both had positive mediation effects on carbon emission trading policy affecting EE. Carbon 103-109 3-hydroxyanthranilate 3,4-dioxygenase Homo sapiens 69-72 34751881-11 2022 Additionally, the spatial spillover effects test showed that the carbon emission trading policy had a positive effect on the EE of the pilot areas but a negative effect on that of the non-pilot areas. Carbon 65-71 3-hydroxyanthranilate 3,4-dioxygenase Homo sapiens 96-99 34603955-3 2021 This retrospective observational study aims to investigate the safety and performance of Hymovis (HYADD-4) injection, a hexadecyl (C-16) HA-derivative, when used to manage symptomatic hip OA in active middle-aged sportsmen over a 24-month observation period. Carbon 131-132 hedgehog interacting protein Homo sapiens 184-187 22525679-10 2012 In a fermentable carbon source such as glucose, the negative GATA factor Dal80 binds to UGA4 promoter; only after the addition of the inducer, the positive factors Uga3, Dal81 and Gln3 interact with the promoter removing Dal80 and leading to gene induction. Carbon 17-23 Uga3p Saccharomyces cerevisiae S288C 164-168 34492331-0 2021 Carbon ion (12C6+) irradiation induces the expression of Klrk1 in lung cancer and optimizes the tumor microenvironment based on the NKG2D/NKG2D-Ls pathway. Carbon 0-6 killer cell lectin-like receptor subfamily K, member 1 Mus musculus 57-62 34492331-0 2021 Carbon ion (12C6+) irradiation induces the expression of Klrk1 in lung cancer and optimizes the tumor microenvironment based on the NKG2D/NKG2D-Ls pathway. Carbon 0-6 killer cell lectin-like receptor subfamily K, member 1 Mus musculus 132-137 34827886-5 2021 In general, the results of fish stomach contents analyses and their associated indices, together with stable carbon and nitrogen isotopes, revealed domination by alien fishes or diet overlaps between both alien and native fish species. Carbon 109-115 COP9 signalosome subunit 2 Homo sapiens 162-167 34329915-4 2021 The empirical results based on the CS-ARDL approach revealed that stock market development, per capita income, and trade expansion invigorated carbon intensity in the South Asian countries. Carbon 143-149 citrate synthase Homo sapiens 35-37 34492331-0 2021 Carbon ion (12C6+) irradiation induces the expression of Klrk1 in lung cancer and optimizes the tumor microenvironment based on the NKG2D/NKG2D-Ls pathway. Carbon 0-6 killer cell lectin-like receptor subfamily K, member 1 Mus musculus 138-143 22245998-0 2012 Activation of HGF/c-Met signaling by ultrafine carbon particles and its contribution to alveolar type II cell proliferation. Carbon 47-53 MET proto-oncogene, receptor tyrosine kinase Rattus norvegicus 18-23 34410096-0 2021 Efficient Photocatalytic Reduction of CO2 to CO Using NiFe2O4@N/C/SnO2 Derived from FeNi Metal-Organic Framework. Carbon 64-65 strawberry notch homolog 1 Homo sapiens 66-69 34400390-1 2021 Using the data from GCC countries, this paper analyses the co-movement between oil price, EU carbon allowance prices, global clean energy index and equity index from three GCC counties, namely, Kuwait, Saudi Arabia and the United Arab Emirates. Carbon 93-99 guanylate cyclase 2C Homo sapiens 172-175 34705862-6 2021 CMPK2 was significantly induced at both RNA and protein levels upon stimulation with TLR4 ligand-LPS and TLR3 ligand-Poly (I:C). Carbon 125-127 toll like receptor 3 Homo sapiens 105-109 22245998-2 2012 The present study aimed to explore the role of HGF and c-Met receptor in ultrafine carbon particle-induced alveolar type II epithelial (type II) cell proliferation. Carbon 83-89 MET proto-oncogene, receptor tyrosine kinase Rattus norvegicus 55-60 34771959-5 2021 The physical and morphological properties of the activated carbon, influenced by carbonization process parameters, were characterized from EDX, X-ray diffraction, SEM analysis, and BET analysis. Carbon 59-65 delta/notch like EGF repeat containing Homo sapiens 181-184 34061465-3 2021 These macrophages were pretreated with rigosertib and then induced with LPS or poly I:C. RESULTS: Rigosertib suppressed LPS or poly I:C-induced expression of inflammatory cytokines (tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and IL-23) in WT bone marrow-derived macrophages while failed to affect the upregulation of TNF-alpha and IL-6 in LPS-treated bone marrow-derived macrophages from MEK1DD mice. Carbon 134-135 interleukin 23, alpha subunit p19 Mus musculus 252-257 22222967-0 2012 Primary alcohols activate human TRPA1 channel in a carbon chain length-dependent manner. Carbon 51-57 transient receptor potential cation channel subfamily A member 1 Homo sapiens 32-37 34431694-5 2021 In a proof-of-principle study, we demonstrate the ability to control a model cooperative interaction, namely, the expression of the enzyme invertase (SUC2) which allows S. cerevisiae to hydrolyze sucrose and utilize it as a carbon source. Carbon 224-230 beta-fructofuranosidase SUC2 Saccharomyces cerevisiae S288C 150-154 22461784-1 2012 ATIC, SHMT2, and SLC46A1 have essential roles in one-carbon (1-C) transfer. Carbon 53-59 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Homo sapiens 0-4 34456507-5 2021 Results: Carbon sequestration (CS) and habitat quality experience significant growth, while water retention did not show any trend. Carbon 9-15 citrate synthase Homo sapiens 31-33 34464868-7 2021 The up-regulation of CHST3, CHST12, CHST13, and CHST15 was directly correlated with C-4 and C-6 sulfation. Carbon 84-85 carbohydrate sulfotransferase 3 Homo sapiens 21-26 34464868-7 2021 The up-regulation of CHST3, CHST12, CHST13, and CHST15 was directly correlated with C-4 and C-6 sulfation. Carbon 84-85 carbohydrate sulfotransferase 13 Homo sapiens 36-42 34464868-7 2021 The up-regulation of CHST3, CHST12, CHST13, and CHST15 was directly correlated with C-4 and C-6 sulfation. Carbon 92-93 carbohydrate sulfotransferase 3 Homo sapiens 21-26 22247542-7 2012 Interestingly, DHHC2 efficiently transferred acyl chains 14 carbons and longer, whereas DHHC3 activity was greatly reduced by acyl-CoAs with chain lengths longer than 16 carbons. Carbon 60-67 zinc finger DHHC-type palmitoyltransferase 2 Homo sapiens 15-20 34832708-4 2021 Using the verified model, the impact of carbon doping concentration in the buffer and the thickness of the unintentionally doped (UID) GaN channel in the transient behavior was estimated. Carbon 40-46 gigaxonin Homo sapiens 135-138 34626114-8 2022 Expression of AMPK and SIRT1 was reduced in gut of 6-month-old fish with poly I:C-treatment, and feeding metformin reversed these declines. Carbon 80-81 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 14-18 34402993-2 2021 Herein, exemplifying carbon nanotubes (CNTs)-stringed metal sulfides superstructure (CSC) assembled by nano-dispersed SnS2 and CoS2 phases, cocktail mediation effect similar to that of high-entropy materials is initially studied in ether-based electrolyte to solve the challenges. Carbon 21-27 sodium voltage-gated channel alpha subunit 11 Homo sapiens 118-122 22428619-7 2012 The microspherical structured and mesoporous Nb-doped TiO(2) is an alternative support to carbon for PEM fuel cells. Carbon 90-96 mucin 1, cell surface associated Homo sapiens 101-104 34147638-2 2021 MMACHC encodes an enzyme crucial for intracellular vitamin B12 metabolism, leading to the accumulation of toxic metabolites e.g. methylmalonic acid (MMA) and homocysteine (Hcy), and secondary disturbances in folate and one-carbon metabolism when not fully functional. Carbon 223-229 methylmalonic aciduria cblC type, with homocystinuria Mus musculus 0-6 34510751-3 2021 Herein, a novel Cu anchored on hollow carbon spheres catalysts (HCS/Cu-x, x represents the mass of CuCl2 added in the system) is designed with controllable copper/carbon heterogenous interfaces. Carbon 38-44 holocarboxylase synthetase Homo sapiens 64-67 34510751-3 2021 Herein, a novel Cu anchored on hollow carbon spheres catalysts (HCS/Cu-x, x represents the mass of CuCl2 added in the system) is designed with controllable copper/carbon heterogenous interfaces. Carbon 38-44 cut like homeobox 1 Homo sapiens 68-72 34510751-3 2021 Herein, a novel Cu anchored on hollow carbon spheres catalysts (HCS/Cu-x, x represents the mass of CuCl2 added in the system) is designed with controllable copper/carbon heterogenous interfaces. Carbon 163-169 holocarboxylase synthetase Homo sapiens 64-67 22242842-6 2012 In the TS of the C-S bond cleavage an increase of the positive charge in the trityl moiety and of the spin density on the ArS group is observed. Carbon 17-18 RIEG2 Homo sapiens 122-125 34081832-5 2021 Co-Immobilization of a ferredoxin NADP + reductase and crotonyl-CoA carboxylase/reductase within a 2,2 -viologen modified hydrogel enabled iterative NADPH recycling and stereoselective formation of (2 S )-ethylmalonyl-CoA, a prospective intermediate towards multi-carbon products from CO 2 , with 92 +- 6 % faradaic efficiency and at a rate of 1.6 +- 0.4 micromol cm -2 h -1 . Carbon 264-270 ferredoxin reductase Homo sapiens 23-50 21960547-7 2012 The NF-kappaB inhibitor pyrrolidine dithiocarbamate attenuated SWCNT-induced airway hyperreactivity, chronic airway inflammation, and MMP12 and cathepsin K expression when administered in vivo, whereas a cathepsin K inhibitor could partially reduce airway hyperreactivity and granulomatous changes in the SWCNT-treated group. Carbon 63-68 matrix metallopeptidase 12 Mus musculus 134-139 34493768-4 2021 According to the fact that C60 fullerene (a sphere-shaped molecule consisting of carbon) has shown inhibitory activity against various protein targets, here the analysis of the potential binding mechanism between SARS-CoV-2 proteins 3CLpro and RdRp with C60 fullerene was done; it has resulted in one and two possible binding mechanisms, respectively. Carbon 81-87 ORF1a polyprotein;ORF1ab polyprotein Severe acute respiratory syndrome coronavirus 2 244-248 34384073-0 2021 CS-CNTs homojunctions prepared by in-situ growth of carbon nanotubes on the surface of porous carbon spheres for lithium-sulfur batteries. Carbon 52-58 citrate synthase Homo sapiens 0-2 34384073-0 2021 CS-CNTs homojunctions prepared by in-situ growth of carbon nanotubes on the surface of porous carbon spheres for lithium-sulfur batteries. Carbon 94-100 citrate synthase Homo sapiens 0-2 34384073-4 2021 Herein, CS-CNTs homojunctions featured with the carbon nanotubes (CNTs) in-situ grown on carbon spheres (CS) is designed and synthesized by simple polymerization and heat treatment. Carbon 48-54 citrate synthase Homo sapiens 8-10 21960547-7 2012 The NF-kappaB inhibitor pyrrolidine dithiocarbamate attenuated SWCNT-induced airway hyperreactivity, chronic airway inflammation, and MMP12 and cathepsin K expression when administered in vivo, whereas a cathepsin K inhibitor could partially reduce airway hyperreactivity and granulomatous changes in the SWCNT-treated group. Carbon 63-68 cathepsin K Mus musculus 144-155 34384073-4 2021 Herein, CS-CNTs homojunctions featured with the carbon nanotubes (CNTs) in-situ grown on carbon spheres (CS) is designed and synthesized by simple polymerization and heat treatment. Carbon 48-54 citrate synthase Homo sapiens 105-107 34384073-4 2021 Herein, CS-CNTs homojunctions featured with the carbon nanotubes (CNTs) in-situ grown on carbon spheres (CS) is designed and synthesized by simple polymerization and heat treatment. Carbon 89-95 citrate synthase Homo sapiens 8-10 21960547-7 2012 The NF-kappaB inhibitor pyrrolidine dithiocarbamate attenuated SWCNT-induced airway hyperreactivity, chronic airway inflammation, and MMP12 and cathepsin K expression when administered in vivo, whereas a cathepsin K inhibitor could partially reduce airway hyperreactivity and granulomatous changes in the SWCNT-treated group. Carbon 63-68 cathepsin K Mus musculus 204-215 34384073-4 2021 Herein, CS-CNTs homojunctions featured with the carbon nanotubes (CNTs) in-situ grown on carbon spheres (CS) is designed and synthesized by simple polymerization and heat treatment. Carbon 89-95 citrate synthase Homo sapiens 105-107 22313376-0 2012 Multiple generations of carbon in the apex chert and implications for preservation of microfossils. Carbon 24-30 apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens 38-42 34427417-5 2021 Endosomal stimulation of TLR3 by adding poly(I:C) in cell culture media or cytoplasmic stimulation of MDA5 by transfecting poly(I:C) resulted in significant increases of TLR3, MDA5, interferon (IFN) beta, and interleukin 8 gene expression levels in wild type (WT) cells. Carbon 130-132 toll like receptor 3 Homo sapiens 170-174 22064602-5 2012 The generation of DHT occurs in large part from adrenal 19-carbon precursor steroids, which are dependent on expression of CYP17A1. Carbon 59-65 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 123-130 34549145-2 2021 Herein, carbon dots derived from Mint leaf extract (M-CDs) via a green method are exploited for versatile applications as a biosensor, reductant, and biomarker. Carbon 8-14 spen family transcriptional repressor Homo sapiens 33-37 22139871-1 2012 Dihydroceramide Delta4-desaturase 1 (DES1) catalyzes the last step of the de novo ceramide biosynthesis, which consists of the introduction of a trans Delta4-double bond in the carbon chain of the dihydroceramide. Carbon 177-183 delta like canonical Notch ligand 4 Rattus norvegicus 22-35 34416676-1 2021 A molecularly imprinted polymer (MIP) with magnetic carbon nanotubes (MCNTs) as carrier was synthesized and used for the enrichment and determination of ferulic acid (FA) by high-performance liquid chromatography (HPLC). Carbon 52-58 glycogen synthase kinase 3 beta Rattus norvegicus 167-169 34416676-2 2021 The morphology and structure of the FA magnetic carbon nanotubes-molecularly imprinted polymers (MCNTs@FA-MIPs) were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, and X-ray diffraction. Carbon 48-54 glycogen synthase kinase 3 beta Rattus norvegicus 36-38 34391473-8 2021 Stimulation with the TLR2, 3 and 4 agonists Pam3CSK4, Poly I:C and LPS, respectively, induced the pro-inflammatory cytokines TNF-alpha and IL-8, while the TLR5 agonist FliC only induced TNF-alpha. Carbon 61-62 toll like receptor 2 Equus caballus 21-34 22259432-1 2012 In the title compound, C(11)H(9)NO(4), the carboxyl group bonded to the six-membered ring lies close to the plane of the 1H-indole ring system [dihedral angle = 13.13 (9) ], whereas the carb-oxy-lic acid group linked to the five-membered ring by a methyl-ene bridge is close to perpendicular [78.85 (9) ]. Carbon 23-24 syntaxin 8 Homo sapiens 43-47 34183356-1 2021 One carbon (1C) metabolism has a key role in metabolic programming with both mitochondrial (m1C) and cytoplasmic (c1C) components. Carbon 4-10 endogenous retrovirus group K member 18 Homo sapiens 114-117 22723860-4 2012 PUFAs, containing at least 18 carbon atoms and three unsaturated bonds, activate TRPA1 to excite primary sensory neurons and enteroendocrine cells. Carbon 30-36 transient receptor potential cation channel subfamily A member 1 Homo sapiens 81-86 34218391-9 2021 The expression of prdm1a was high while the expression of bcl6aa was low, and vice versa, detected in the spleen after stimulation with LPS or polyI:C. Carbon 149-150 B-cell lymphoma 6 protein Oryzias latipes 58-64 34927868-3 2021 Herein, a micro-nano structure with vertically aligned WSe2 nanoflakes anchored tightly on a micron-sized carbon sphere (WSe2 /CS) is successfully constructed via combining the molecular coupling and self-assembly strategy. Carbon 106-112 citrate synthase Homo sapiens 127-129 34927877-3 2021 The ionization of elements and their recombination process during arc discharge allows the simultaneous incorporation of single metal atoms (Mn, Fe, Co, Ni, and Pt) into the crystalline carbon lattice during the formation of carbon nanohorns (CNHs) and N-doped arc graphene. Carbon 186-192 activity regulated cytoskeleton associated protein Homo sapiens 66-69 21930280-3 2011 The experimental pollutant isotherms, evaluated using the Langmuir model, showed that only 8-12% and 21-32% of the BET surface area was available for phenol and dopamine, respectively, which is far below the performance of activated carbons. Carbon 233-240 delta/notch like EGF repeat containing Homo sapiens 115-118 34927877-3 2021 The ionization of elements and their recombination process during arc discharge allows the simultaneous incorporation of single metal atoms (Mn, Fe, Co, Ni, and Pt) into the crystalline carbon lattice during the formation of carbon nanohorns (CNHs) and N-doped arc graphene. Carbon 225-231 activity regulated cytoskeleton associated protein Homo sapiens 66-69 34386635-4 2021 SEM and Raman measurements confirm the formation of TiO2 anatase around 400 C. The observation of an exothermic peak around 260 C in the TGA/DTA measurements confirms the decomposition of carbon chains to form graphite. Carbon 190-196 T-box transcription factor 1 Homo sapiens 139-142 34132719-3 2021 It is noteworthy that ligands HL2- act as a long-distance link and further connect the Dy2 fragments into an infinite 1D chain due to the conformational flexibility resulting from the rotatable C-C bond in 5. Carbon 194-195 intelectin 2 Homo sapiens 30-33 34132719-3 2021 It is noteworthy that ligands HL2- act as a long-distance link and further connect the Dy2 fragments into an infinite 1D chain due to the conformational flexibility resulting from the rotatable C-C bond in 5. Carbon 196-197 intelectin 2 Homo sapiens 30-33 34299056-7 2021 In conclusion, we demonstrate here that TIGAR is upregulated in stimulated human lymphocytes through the PI3K/AKT signaling pathway, which contributes to the redirection of the carbon flux to the PPP. Carbon 177-183 TP53 induced glycolysis regulatory phosphatase Homo sapiens 40-45 34230520-2 2021 The activated carbon products were characterized by FTIR, SEM-EDS, Raman spectroscopy, and BET analysis. Carbon 14-20 delta/notch like EGF repeat containing Homo sapiens 91-94 34230520-5 2021 The BET surface area and micropore volume of the activated carbons are 426.8125-870.4732 m2/g and 0.102390-0.215473 cm3/g, respectively. Carbon 59-66 delta/notch like EGF repeat containing Homo sapiens 4-7 34073998-5 2021 Herein, we report the use of polydopamine-functionalized multi-walled carbon nanotubes (PDA-MWCNTs) to effectively attach Ru(dmo-bpy)2Cl2 and GDH onto screen-printed carbon electrodes (SPCEs) without requiring a cross-linker. Carbon 70-76 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 142-145 34073998-5 2021 Herein, we report the use of polydopamine-functionalized multi-walled carbon nanotubes (PDA-MWCNTs) to effectively attach Ru(dmo-bpy)2Cl2 and GDH onto screen-printed carbon electrodes (SPCEs) without requiring a cross-linker. Carbon 166-172 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 142-145 34168844-3 2021 Here, we find that the electrocatalytic activity of single-site MOFs toward the oxygen reduction reaction (ORR) can be tuned by using carbon nanomaterials, i.e., carbon nanotubes and graphene, as supports through MOF-support interactions in the manner of geometric and electronic effects. Carbon 134-140 lysine acetyltransferase 8 Homo sapiens 213-216 34168844-3 2021 Here, we find that the electrocatalytic activity of single-site MOFs toward the oxygen reduction reaction (ORR) can be tuned by using carbon nanomaterials, i.e., carbon nanotubes and graphene, as supports through MOF-support interactions in the manner of geometric and electronic effects. Carbon 162-168 lysine acetyltransferase 8 Homo sapiens 213-216 34927885-7 2021 Interestingly, the oxygen electrode activity (DeltaE) for (Fe,Co)-SA/CS and commercial Pt/C-RuO2 is calculated to be 0.73 V, exhibiting the bifunctional catalytic activity of (Fe,Co)-SA/CS. Carbon 90-91 citrate synthase Homo sapiens 186-188 34163619-3 2021 Accordingly, 3a reacted with two equivalents of Li/naphthalene by reductive cleavage of a P-C bond of one of the PC4 heterocycles. Carbon 92-93 proprotein convertase subtilisin/kexin type 4 Homo sapiens 113-116 35405246-4 2022 The modeling indicated that drier climatic conditions are associated with a tendency of elevated Mn concentrations, whereas high Fe concentrations tend to be found in a more humid climate with elevated levels of soil organic carbon. Carbon 225-231 homeostatic iron regulator Homo sapiens 124-131 35429555-5 2022 In this study, we found that the light absorption ability of WSOC treated with PS1 was higher than that of PS2 due to the extinction of suspended particles (e.g., black carbon) with particle size between 0.20 mum and 0.45 mum, although the concentrations of WSOC treated with PS1 and PS2 were very close. Carbon 169-175 taste 2 receptor member 62 pseudogene Homo sapiens 79-82 35429555-5 2022 In this study, we found that the light absorption ability of WSOC treated with PS1 was higher than that of PS2 due to the extinction of suspended particles (e.g., black carbon) with particle size between 0.20 mum and 0.45 mum, although the concentrations of WSOC treated with PS1 and PS2 were very close. Carbon 169-175 taste 2 receptor member 62 pseudogene Homo sapiens 276-279 35636096-5 2022 Finally, the molecular docking analysis implied that the carbonyl and hydroxy groups at the C-11/C-6" of 5 and 6 had a good binding affinity with ERK. Carbon 92-93 complement C6 Homo sapiens 97-112 35219199-0 2022 Boron-induced activation of Ru nanoparticles anchored on carbon nanotubes for the enhanced pH-independent hydrogen evolution reaction. Carbon 57-63 phenylalanine hydroxylase Homo sapiens 91-93 35429516-6 2022 After carbonization, the selected lignin-derived carbon foams possessed well porous structures with bulk densities of 0.52 or 0.62 g cm-3, superior integrity with strength properties of around 10 MPa, BET surface areas of 143.29 or 325.86 m2 g-1, and many other attractive properties. Carbon 49-55 delta/notch like EGF repeat containing Homo sapiens 201-204 35603929-2 2022 It is a mucin-degrading bacterium that can colonise intestines of mammals such as humans and mice by utilising mucin as the only nitrogen and carbon source. Carbon 142-148 LOC100508689 Homo sapiens 8-13 35603929-2 2022 It is a mucin-degrading bacterium that can colonise intestines of mammals such as humans and mice by utilising mucin as the only nitrogen and carbon source. Carbon 142-148 LOC100508689 Homo sapiens 111-116 35581154-3 2022 Herein, hollow N-doped carbon nanocubes confined petal-like ZnS/SnS2 heterostructures (ZnS/SnS2 @NC) as a conceptually novel host for Li-S batteries are reported. Carbon 23-29 sodium voltage-gated channel alpha subunit 11 Homo sapiens 64-68 35581154-3 2022 Herein, hollow N-doped carbon nanocubes confined petal-like ZnS/SnS2 heterostructures (ZnS/SnS2 @NC) as a conceptually novel host for Li-S batteries are reported. Carbon 23-29 sodium voltage-gated channel alpha subunit 11 Homo sapiens 91-95 35092783-10 2022 The results also show that global warming will lead to higher energy use and carbon emissions in tropical regions within the near future, while stringent mitigation strategies aligned with RCP 2.6 can reverse the trend after two decades. Carbon 77-83 CGRP receptor component Homo sapiens 189-192 35411903-3 2022 From these simulations, we identify that PAN/cellulose (CL) blend manifests the highest carbon yield and the most substantial all-carbon ring formation. Carbon 88-94 adenosine deaminase 2 Homo sapiens 41-44 35411903-3 2022 From these simulations, we identify that PAN/cellulose (CL) blend manifests the highest carbon yield and the most substantial all-carbon ring formation. Carbon 130-136 adenosine deaminase 2 Homo sapiens 41-44 35411903-5 2022 We trace the pathway of gasification and carbonization of PAN/CL to elaborate the mechanism of the formation of all-carbon ring networks. Carbon 116-122 adenosine deaminase 2 Homo sapiens 58-64 35411903-8 2022 Our simulation results show the most extensive all-carbon ring cluster and graphitic structure growths for PAN/CL. Carbon 51-57 adenosine deaminase 2 Homo sapiens 107-113 35506189-8 2022 Increased prohormone convertase 1/3 was detected in glucagon-positive cells, and glucagon-like peptide 1 (GLP-1) area was elevated in grafts from mice that displayed hyperglycemia or elevated plasma PI/C ratios, demonstrating intra-islet incretin production in metabolically challenged human islet grafts. Carbon 202-203 glucagon Mus musculus 81-104 35506189-8 2022 Increased prohormone convertase 1/3 was detected in glucagon-positive cells, and glucagon-like peptide 1 (GLP-1) area was elevated in grafts from mice that displayed hyperglycemia or elevated plasma PI/C ratios, demonstrating intra-islet incretin production in metabolically challenged human islet grafts. Carbon 202-203 glucagon Mus musculus 106-111 35112714-6 2022 In this work, porous graphitized carbon separation method coupled with mass spectrometry was used to characterize the N- and O- glycosylation profiles of Gag VLPs produced in HEK293 cells. Carbon 33-39 Pr55(Gag) Human immunodeficiency virus 1 154-157 35533486-4 2022 Inspired by the traditional handicraft of candied haw, ZnO/porous carbon micron tubes (ZnO/PCMT), are achieved by conducting a dip-coating and thermal etching process on recycling the abandoned Sycamore microtube. Carbon 66-72 isoprenylcysteine carboxyl methyltransferase Homo sapiens 91-95 35477575-0 2022 One step synthesis of efficient red emissive carbon dots and their bovine serum albumin composites with enhanced multi-photon fluorescence for in vivo bioimaging. Carbon 45-51 albumin Mus musculus 74-87 35436090-3 2022 The dualism of N-dopants and binary metals lower the d-band centers of both Fe and Co in the Fe,Co,N-C catalyst, improving the overpotential of the overall electrocatalytic processes (DeltaEORR-OER = 0.74 +- 0.02 V vs RHE). Carbon 101-102 factor interacting with PAPOLA and CPSF1 Homo sapiens 218-221 35411515-4 2022 Second, the structural path analysis for environmental input-output analysis (EIOA-SPA) model is used to quantify the transfer of carbon emissions between sectors in various regions. Carbon 130-136 surfactant protein A1 Homo sapiens 83-86 35397015-2 2022 In this work, a three-dimensional pore structure of alkali-activated nitrogen-doped graphene (aN-G) was used as an electrode modification material, and a label-free electrochemical immunosensor for the sensitive detection of CTGF was successfully constructed by the formation of an amide bond between amino groups in protein and carboxyl groups on the carbon surface. Carbon 352-358 cellular communication network factor 2 Homo sapiens 225-229 35431695-0 2022 Carbon Ion Induces Cell Death and G2/M Arrest Through pRb/E2F1Chk2/Cdc2 Signaling Pathway in X-ray Resistant B16F10 Melanoma Cells. Carbon 0-6 cyclin-dependent kinase 1 Mus musculus 67-71 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 113-119 sodium voltage-gated channel alpha subunit 11 Homo sapiens 29-33 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 113-119 sodium voltage-gated channel alpha subunit 11 Homo sapiens 132-136 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 235-241 sodium voltage-gated channel alpha subunit 11 Homo sapiens 29-33 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 235-241 sodium voltage-gated channel alpha subunit 11 Homo sapiens 132-136 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 290-296 sodium voltage-gated channel alpha subunit 11 Homo sapiens 29-33 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 290-296 sodium voltage-gated channel alpha subunit 11 Homo sapiens 132-136 35142111-3 2022 The volume balance between SnS2 nanosheets and hollow carbon nanoreactors is reached to accommodate the expansion of SnS2 during cycles by controlling the thickness of SnO2 shells, which achieves the best space utilization. Carbon 54-60 sodium voltage-gated channel alpha subunit 11 Homo sapiens 117-121 35335527-2 2022 In this work, the synthesis of nanocomposites of poly(methacrylic acid) (PMAA) grafted onto carbon nanotubes (CNTs) functionalized with poly(amidoamine) (PAMAM) dendrimer by semicontinuous heterophase polymerization SHP, at three different methacrylic acid (MAA) dosing rates, is reported. Carbon 92-98 nuclear receptor subfamily 0 group B member 2 Homo sapiens 216-219 35601978-1 2022 We developed an electrochemical biosensing platform using gold-clusters, cysteamine, the spike protein of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antigen and bovine serum albumin on a glassy carbon electrode able to determine the SARS-CoV-2 spike antibody. Carbon 216-222 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 89-94 35601978-1 2022 We developed an electrochemical biosensing platform using gold-clusters, cysteamine, the spike protein of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antigen and bovine serum albumin on a glassy carbon electrode able to determine the SARS-CoV-2 spike antibody. Carbon 216-222 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 266-271 35248023-7 2022 Proteomic analysis supported the role of Znf1 and Bud21 in modulating levels of proteins associated with carbon metabolism, xylose utilisation, ribosomal protein synthesis, and others. Carbon 105-111 Bud21p Saccharomyces cerevisiae S288C 50-55 35359273-2 2022 In this study, an amperometric glucose biosensor (GOD/CS/PR/GCE) based on layer-by-layer of glucose oxidase (GOD), chitosan (CS) and pyrite (PR) on a glassy carbon electrode (GCE) was fabricated through electrostatic force. Carbon 157-163 citrate synthase Homo sapiens 54-56 35359273-2 2022 In this study, an amperometric glucose biosensor (GOD/CS/PR/GCE) based on layer-by-layer of glucose oxidase (GOD), chitosan (CS) and pyrite (PR) on a glassy carbon electrode (GCE) was fabricated through electrostatic force. Carbon 157-163 citrate synthase Homo sapiens 125-127 35064740-0 2022 Hollow Cobalt Oxide/Carbon Hybrids Aid Metabolic Encoding for Active Systemic Lupus Erythematosus during Pregnancy. Carbon 20-26 activation induced cytidine deaminase Homo sapiens 35-38 35323418-3 2022 The sensor is composed of single-walled carbon nanotubes (SWCNTs) functionalized with monoclonal antibodies that bind to the spike protein of SARS-CoV-2. Carbon 40-46 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 125-130 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 42-43 toll like receptor 3 Homo sapiens 68-72 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 42-43 toll like receptor 3 Homo sapiens 170-174 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 42-43 toll like receptor 3 Homo sapiens 216-220 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 136-137 toll like receptor 3 Homo sapiens 68-72 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 160-161 toll like receptor 3 Homo sapiens 68-72 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 160-161 toll like receptor 3 Homo sapiens 170-174 35203701-7 2022 We conclude that LL-37 potentiates poly I:C-induced upregulation of TLR3 through a mechanism that may involve enhanced import of poly I:C and that LL-37/poly I:C-induced TLR3 expression is associated with downstream TLR3 signaling and sensitive to inhibition of NF-kappaB activity. Carbon 160-161 toll like receptor 3 Homo sapiens 216-220 35119260-12 2022 Our findings show that carbon modifiers facilitated surface reconstruction and regulated CO2 diffusion to suppress HER and improve the C2-3 product selectivity. Carbon 23-29 nucleolin Homo sapiens 135-139 35229526-5 2022 The gene abundance of methanogenic mcrA, sulfate-reducing bacteria Dsr, and carbon-fixing CbbL were significantly up-regulated in the LF, while that of methanotrophs pmoA, iron-reducing bacteria Geo, and denitrifying bacteria nosZ were significantly up-regulated in the LN, DCK and LCK, respectively. Carbon 76-82 deoxycytidine kinase Homo sapiens 274-277 35062515-1 2022 This work summarizes the electrochemical response of a salicylic acid-based carbon electrode for use as a novel solid-state reference electrode in a redox-based pH sensor. Carbon 76-82 phenylalanine hydroxylase Homo sapiens 161-163 34319854-5 2021 Multiwalled carbon nanotubes catalyzed ozonation removes 85% COD and 48% TOC removal within 180 min at pH 9 and 74% COD and 36% TOC removal was observed for activated carbon catalyzed ozonation for the same experimental conditions. Carbon 12-18 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 61-64 34319854-5 2021 Multiwalled carbon nanotubes catalyzed ozonation removes 85% COD and 48% TOC removal within 180 min at pH 9 and 74% COD and 36% TOC removal was observed for activated carbon catalyzed ozonation for the same experimental conditions. Carbon 12-18 phenylalanine hydroxylase Homo sapiens 103-105 34319854-5 2021 Multiwalled carbon nanotubes catalyzed ozonation removes 85% COD and 48% TOC removal within 180 min at pH 9 and 74% COD and 36% TOC removal was observed for activated carbon catalyzed ozonation for the same experimental conditions. Carbon 167-173 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 116-119 34286736-2 2021 Mechanistic studies showed that coordinatively unsaturated eta2-arene intermediates are responsible for the selective activation of benzylic, not aromatic C-H bonds and formation of stable benzyl complexes after trapping with a phosphine ligand. Carbon 155-156 DNA polymerase iota Homo sapiens 59-63 34651085-3 2021 To develop a 2-step formate reduction pathway, we screened natural variants of acyl-CoA synthetase (ACS) and acylating aldehyde dehydrogenase (ACDH) for activity on one-carbon substrates and identified active and highly expressed homologs of both enzymes. Carbon 169-175 acyl-CoA synthetase short chain family member 2 Homo sapiens 79-98 34651085-3 2021 To develop a 2-step formate reduction pathway, we screened natural variants of acyl-CoA synthetase (ACS) and acylating aldehyde dehydrogenase (ACDH) for activity on one-carbon substrates and identified active and highly expressed homologs of both enzymes. Carbon 169-175 acyl-CoA synthetase short chain family member 2 Homo sapiens 100-103 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 61-67 insulin receptor Homo sapiens 199-203 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 61-67 solute carrier family 2 member 4 Homo sapiens 235-240 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 69-71 insulin receptor Homo sapiens 199-203 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 69-71 solute carrier family 2 member 4 Homo sapiens 235-240 34193600-4 2021 Using a line of CRISPR-generated Arg1-YFP reporter knock-in mice, we have determined that a subset of tumor-associated macrophages represent the major Arg1-expressing cell type following poly(I:C)/IFN stimulation. Carbon 194-196 arginase, liver Mus musculus 151-155 34242391-6 2021 Accordingly, a small-molecule PAR2 inhibitor suppressed poly(I:C)/thrombin-induced leukocyte-endothelial adhesion, cytokine production, and endothelial tissue factor expression. Carbon 63-65 F2R like trypsin receptor 1 Homo sapiens 30-34 34244482-1 2021 Glycine decarboxylase (GLDC) is a key enzyme of glycine cleavage system that converts glycine into one-carbon units. Carbon 103-109 glycine decarboxylase Homo sapiens 0-21 34244482-1 2021 Glycine decarboxylase (GLDC) is a key enzyme of glycine cleavage system that converts glycine into one-carbon units. Carbon 103-109 glycine decarboxylase Homo sapiens 23-27 34295263-6 2021 In brief, carbon and nitrogen redistribution to challenged tissues (muscle and lungs) for fuel replenishment and cell regeneration against abdominal adipose tissue seems to be the fundamental mechanism underlying the intensity-dependent fat loss effect of exercise. Carbon 10-16 FAT atypical cadherin 1 Homo sapiens 237-240 34295263-8 2021 Therefore, meal arrangement at the time when muscle has the greatest reconstruction demand for carbon and nitrogen could decrease abdominal fat accumulation while increasing muscle mass and tissue repair. Carbon 95-101 FAT atypical cadherin 1 Homo sapiens 140-143 34745555-3 2021 Herein, we describe the development of a highly stable and active immobilized PAL-biocatalyst obtained through site-specific covalent immobilization onto single-walled carbon nanotubes (SWCNTs), employing maleimide/thiol coupling of engineered enzymes containing surficial Cys residues. Carbon 168-174 SHC binding and spindle associated 1 Homo sapiens 78-81 35635968-3 2022 The BP-CdTe QDs modified glassy carbon electrode (GCE) firstly captured the anti-Abeta1, and then the target Abeta. Carbon 32-38 AA1 Homo sapiens 81-87 35398746-0 2022 Cascade reaction biosensor based on Cu/N co-doped two-dimensional carbon-based nanozyme for the detection of lactose and beta-galactosidase. Carbon 66-72 galactosidase beta 1 Homo sapiens 121-139 35508278-11 2022 Real-time metabolic measurements of oxygen consumption rate and extracellular acidification rate revealed that SMTNL1 improved glycolysis and promoted the utilization of alternative carbon fuels. Carbon 182-188 smoothelin-like 1 Mus musculus 111-117 35612874-1 2022 We present here a novel strategy based on the covalent grafting of a C-functionalized Ni-cyclam complex onto glassy carbon to achieve heterogeneous electrocatalytic CO2 reduction in neutral water at low overpotential (-500 mV vs. NHE), with moderate turnover number (TON = 454), high selectivity (85% CO produced) and good faradaic efficiency (56% CO). Carbon 116-122 solute carrier family 9 member C1 Homo sapiens 230-233 35548860-4 2022 We evidence here, by quantitative operando X-ray absorption spectroscopy, that the initial Ir single atoms are coordinated with four light atoms i.e., Ir-X4 (X = C/N/O) with an oxidation state of +3.2. Carbon 162-163 iroquois homeobox 4 Homo sapiens 151-156 35611945-3 2022 The detection limits (3sigma method) of HQ, CA, and RE on the glassy carbon electrode (GCE) modified with pGr-MoS2 are 10-13, 10-12, and 10-8 M (i.e., 0.1 pM, 1 pM, and 10 nM), respectively, and are the lowest reported so far for the isomers. Carbon 69-75 progesterone receptor Homo sapiens 106-109 35596669-11 2022 CONCLUSION: The growth of the yield ratio of the single- and double-strand breaks (SSB and DSB) with the particle energy was estimated for protons to be about two times that of alphas and 92 times that of carbon ions. Carbon 205-211 small RNA binding exonuclease protection factor La Homo sapiens 83-86 35629708-1 2022 TiO2-based mixed oxide-carbon composite supports have been suggested to provide enhanced stability for platinum (Pt) electrocatalysts in polymer electrolyte membrane (PEM) fuel cells. Carbon 23-29 mucin 1, cell surface associated Homo sapiens 167-170 35104525-1 2022 Return of biomass-derived biochar (BC) into soil has been considered as one of the carbon sequestration (CS) methods. Carbon 83-89 citrate synthase Homo sapiens 105-107 35352423-2 2022 Subsequent treatment with base resulted in C-N bond formation to yield a mu 3 - eta 2 : eta 2 -1-azabutadien-4-yl complex, ((Cp*Ru) 3 ( mu 3 -CH)( mu 3 - eta 2 : eta 2 -NH=CH-CMe=CH-)) + ( 6a ). Carbon 43-44 DNA polymerase iota Homo sapiens 88-93 35352423-2 2022 Subsequent treatment with base resulted in C-N bond formation to yield a mu 3 - eta 2 : eta 2 -1-azabutadien-4-yl complex, ((Cp*Ru) 3 ( mu 3 -CH)( mu 3 - eta 2 : eta 2 -NH=CH-CMe=CH-)) + ( 6a ). Carbon 43-44 DNA polymerase iota Homo sapiens 162-167 35588657-9 2022 Thereby, C-316-1 inhibited the Hsp90-Cdc37 complex formation and led to a significant decrease in RIPK1, which in turn reduced necroptosis. Carbon 9-10 cell division cycle 37, HSP90 cochaperone Homo sapiens 37-42 35588657-10 2022 Moreover, C-316-1 treatment did not protect against kidney injury in vivo and in vitro when Hsp90 was knocked down and R46, E47, and S50 in Cdc37 binding site of Hsp90 might form an important active pocket with C-316-1. Carbon 211-212 cell division cycle 37, HSP90 cochaperone Homo sapiens 140-145 35183049-0 2022 Multi-walled carbon nanotubes inhibit potential detoxification of dioxin-mediated toxicity by blocking the nuclear translocation of aryl hydrocarbon receptor. Carbon 13-19 aryl hydrocarbon receptor Homo sapiens 132-157 35183049-5 2022 Multi-walled carbon nanotubes (MWCNTs) inhibited the translocation of aryl hydrocarbon receptor (AhR) from cytosol to the nucleus, leading to the downregulation of cytochrome P450 family 1 subfamily A member 1 (CYP1A1) and inhibition of detoxification function. Carbon 13-19 aryl hydrocarbon receptor Homo sapiens 70-95 35183049-5 2022 Multi-walled carbon nanotubes (MWCNTs) inhibited the translocation of aryl hydrocarbon receptor (AhR) from cytosol to the nucleus, leading to the downregulation of cytochrome P450 family 1 subfamily A member 1 (CYP1A1) and inhibition of detoxification function. Carbon 13-19 aryl hydrocarbon receptor Homo sapiens 97-100 35228084-2 2022 For achieving highly sensitive in-situ detection of dissolved furfural in transformer oil with good reproducibility, flower-like silver nanoparticles modified with carbon nanotubes (CNTs@Ag-F-AgNPs) was synthesized by a combination of electroless silver plating and redox method. Carbon 164-170 angiopoietin like 6 Homo sapiens 187-191 35567530-6 2022 CLE2 and CLE3 genes responded to carbon-deficient conditions. Carbon 33-39 CLAVATA3/ESR-RELATED 3 Arabidopsis thaliana 9-13 35586132-1 2022 Carbon storage (CS) is closely linked to the global challenge of climate change. Carbon 0-6 citrate synthase Homo sapiens 16-18 35586132-2 2022 Land use/cover (LULC) change is the main factor driving changes in CS, and evaluating the impact of LULC changes on CS is important for carbon balance. Carbon 136-142 citrate synthase Homo sapiens 67-69 35586132-2 2022 Land use/cover (LULC) change is the main factor driving changes in CS, and evaluating the impact of LULC changes on CS is important for carbon balance. Carbon 136-142 citrate synthase Homo sapiens 116-118 35568216-3 2022 To improve the performance of metal-organic framework (MOF)-derived carbons (MDCs) in dye adsorption, an MDC, derived from a MOF (MAF-6), was oxidatively functionalized with ammonium persulfate solutions (APSs). Carbon 68-75 C-C motif chemokine ligand 22 Homo sapiens 105-108 35057208-2 2022 The reaction mechanism found involves metalation of an N-H residue of the carbene ligand by the catalyst Ag2O and the formation of a key transition state showing a mu-eta2:eta2 coordination of the formamidinyl ligand between manganese and silver, which allows a translocation process of Mn(I) and silver(I) ions between the carbene carbon atom and the nitrogen atom, before the formation of the formamidine ligand is completed. Carbon 332-338 DNA polymerase iota Homo sapiens 167-171 35057208-2 2022 The reaction mechanism found involves metalation of an N-H residue of the carbene ligand by the catalyst Ag2O and the formation of a key transition state showing a mu-eta2:eta2 coordination of the formamidinyl ligand between manganese and silver, which allows a translocation process of Mn(I) and silver(I) ions between the carbene carbon atom and the nitrogen atom, before the formation of the formamidine ligand is completed. Carbon 332-338 DNA polymerase iota Homo sapiens 172-176 35021150-5 2022 Importantly, UCA1 specifically bound to and facilitated the combination of hnRNP I/L to the promoter of glutamic pyruvate transaminase 2 (GPT2), an enzyme transferring glutamate to alpha-ketoglutarate, resulting in upregulated expression of GPT2 and enhanced glutamine-derived carbons in the TCA cycle. Carbon 277-284 urothelial cancer associated 1 Homo sapiens 13-17 34969844-0 2022 Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase. Carbon 24-30 decaprenyl diphosphate synthase subunit 1 Homo sapiens 56-85 34969844-0 2022 Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase. Carbon 31-37 decaprenyl diphosphate synthase subunit 1 Homo sapiens 56-85 34969844-6 2022 This mechanism adds to the known pathways for transformation of the carbon-centered radical in Fe/2OG enzymes and suggests what types of substrate modification are likely tolerable in DPS-catalyzed production of deoxypodophyllotoxin analogs. Carbon 68-74 decaprenyl diphosphate synthase subunit 1 Homo sapiens 184-187 35543782-2 2022 In this paper, we construct an analytical framework that includes a manufacturer and a retailer to explore the value of cooperative ER under the carbon cap-and-trade mechanism (CCTM). Carbon 145-151 epiregulin Homo sapiens 132-134 22004832-2 2011 A total of 24 activated carbons with different microporosity and BET surface area were created. Carbon 24-31 delta/notch like EGF repeat containing Homo sapiens 65-68 35533403-7 2022 For TCBQ, the chlorine atoms cause the olefinic carbons to carry more positive atomic charges, and then, HO2- preferred to add to the olefinic carbons, which might induce the formation of the hydroxyl radical ( OH). Carbon 48-55 heme oxygenase 2 Homo sapiens 105-108 35533403-7 2022 For TCBQ, the chlorine atoms cause the olefinic carbons to carry more positive atomic charges, and then, HO2- preferred to add to the olefinic carbons, which might induce the formation of the hydroxyl radical ( OH). Carbon 143-150 heme oxygenase 2 Homo sapiens 105-108 21952237-8 2011 Poly(I:C) was also shown to induce interferon (IFN)-beta mRNA expression in trophoblasts. Carbon 7-8 interferon beta 1 Homo sapiens 35-56 35428033-0 2022 Improved Li storage performance of SnO nanodisc on SnO2Quantum dots embedded carbon matrix. Carbon 77-83 strawberry notch homolog 1 Homo sapiens 35-38 35428033-4 2022 A facile and scalable fabrication of SnO nanodisc decorated on SnO2 quantum dots embedded carbon (SnOx@C) is reported in the present study. Carbon 90-96 strawberry notch homolog 1 Homo sapiens 37-40 35144080-8 2022 The results show that carbon residues in the PC fly ash mainly have the shorter and branched aliphatic side chains with lower A(CH2)/A(CH3) value. Carbon 22-28 COP9 signalosome subunit 3 Drosophila melanogaster 135-138 21946106-4 2011 The IC50 values of C-721 were 6.2 and 22.6muM, respectively, for cyclooxygenase-2 (COX-2) mediated PGE2 and inducible nitric oxide (iNOS)-mediated NO production. Carbon 5-6 prostaglandin-endoperoxide synthase 2 Mus musculus 65-81 35249365-8 2022 Results of proteome analysis of control and DKK1-knockdown human pulmonary artery endothelial cells identified a significantly differentially expressed protein, SHMT2 (serine hydroxymethyltransferase 2), a key metabolic enzyme in one-carbon metabolism, as a novel DKK1 target. Carbon 234-240 dickkopf WNT signaling pathway inhibitor 1 Homo sapiens 44-48 21946106-4 2011 The IC50 values of C-721 were 6.2 and 22.6muM, respectively, for cyclooxygenase-2 (COX-2) mediated PGE2 and inducible nitric oxide (iNOS)-mediated NO production. Carbon 5-6 prostaglandin-endoperoxide synthase 2 Mus musculus 83-88 21962654-0 2011 A new flow injection preconcentration method based on multiwalled carbon nanotubes for the ETA-AAS determination of Cd in urine. Carbon 66-72 endothelin receptor type A Homo sapiens 91-94 35470541-0 2022 Fe-doped MOF-derived N-rich porous carbon nanoframe for H2 S cataluminescence sensing. Carbon 35-41 lysine acetyltransferase 8 Homo sapiens 9-12 21916448-0 2011 Multiwalled carbon nanotubes anchored with SnS2 nanosheets as high-performance anode materials of lithium-ion batteries. Carbon 12-18 sodium voltage-gated channel alpha subunit 11 Homo sapiens 43-47 35470541-2 2022 In this work, Fe-doped MOF-derived N-rich porous carbon nanoframe was successfully fabricated by pyrolysis of Fe-doped ZIF-8 in an Ar atmosphere at a temperature of 900 C, and used for H2 S cataluminescence sensing. Carbon 49-55 lysine acetyltransferase 8 Homo sapiens 23-26 22267895-0 2011 Photocatalytic activity of CdS and Ag(2)S quantum dots deposited on poly(amidoamine) functionalized carbon nanotubes. Carbon 100-106 angiotensin II receptor type 1 Homo sapiens 35-41 35457954-6 2022 SnS2/carbon composites have been considered to be a most promising approach to addressing the abovementioned issues. Carbon 5-11 sodium voltage-gated channel alpha subunit 11 Homo sapiens 0-4 35457954-7 2022 Therefore, this review summarizes the current progress in the synthesis of SnS2/carbon anode materials and their Li-ion storage properties, with special attention to the developments in Li-based technology, attributed to its immense current importance and promising prospects. Carbon 80-86 sodium voltage-gated channel alpha subunit 11 Homo sapiens 75-79 22068497-11 2011 Evidently, MaeB contributed to the NADPH generation needed for bacterial growth on two carbon compounds. Carbon 87-93 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) Escherichia coli str. K-12 substr. MG1655 11-15 35379968-3 2022 Our concept of oxidative onioation, where white phosphorus is selectively converted into triflate salts of versatile P1 transfer reagents such as (P(LN)3)(OTf)3 (LN is a cationic, N-based substituent; that is, 4-dimethylaminopyridinio), provides a convenient alternative for the implementation of P-O, P-N and P-C bonds while circumventing the use of PCl3. Carbon 312-313 PHD finger protein 19 Homo sapiens 351-355 34998743-3 2022 Herein, a hollow carbon sphere/porous carbon flake (HCS/PCF) framework is fabricated through template carbonization of plastic waste. Carbon 17-23 holocarboxylase synthetase Homo sapiens 52-55 34998743-3 2022 Herein, a hollow carbon sphere/porous carbon flake (HCS/PCF) framework is fabricated through template carbonization of plastic waste. Carbon 38-44 holocarboxylase synthetase Homo sapiens 52-55 21822505-2 2011 We report their high pressure CO(2) adsorption isotherms (273 K) that show for FAU-ZTC the highest carbon capture capacity among published carbonaceous materials and competitive data with the best organic and inorganic adsorbing frameworks ever-known (zeolites and mesoporous silicas, COFs and MOFs). Carbon 99-105 FAU ubiquitin like and ribosomal protein S30 fusion Homo sapiens 79-82 35142111-0 2022 Tailoring the Void Space Using Nanoreactors on Carbon Fibers to Confine SnS2 Nanosheets for Ultrastable Lithium/Sodium-Ion Batteries. Carbon 47-53 sodium voltage-gated channel alpha subunit 11 Homo sapiens 72-76 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 71-77 sodium voltage-gated channel alpha subunit 11 Homo sapiens 29-33 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 71-77 sodium voltage-gated channel alpha subunit 11 Homo sapiens 132-136 21804546-2 2011 Using a metabolomics approach with isotope labeling, we found that in some cancer cells a relatively large amount of glycolytic carbon is diverted into serine and glycine metabolism through phosphoglycerate dehydrogenase (PHGDH). Carbon 128-134 phosphoglycerate dehydrogenase Homo sapiens 190-220 21804546-2 2011 Using a metabolomics approach with isotope labeling, we found that in some cancer cells a relatively large amount of glycolytic carbon is diverted into serine and glycine metabolism through phosphoglycerate dehydrogenase (PHGDH). Carbon 128-134 phosphoglycerate dehydrogenase Homo sapiens 222-227 35089338-0 2022 The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis. Carbon 104-110 carbon/nitrogen insensitive 1 Arabidopsis thaliana 56-61 21146842-7 2011 Some spots were identified as metabolic enzymes related to central carbon metabolism such as malic enzyme, glyceraldehyde-3-phosphate dehydrogenase, monodehydroascorbate reductase and alanine aminotransferase. Carbon 67-73 monodehydroascorbate reductase Arabidopsis thaliana 149-179 35089338-4 2022 Here, we report that the Arabidopsis thaliana trans-Golgi network/early endosome (TGN/EE) localized SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein SYP61 interacts with the transmembrane ubiquitin ligase ATL31, a key regulator of resistance to disrupted carbon (C)/nitrogen/(N)-nutrient conditions. Carbon 292-298 carbon/nitrogen insensitive 1 Arabidopsis thaliana 242-247 35234919-0 2022 Concerted action: SYP61 and ATL31 cooperatively regulate the carbon/nitrogen nutrient response in Arabidopsis. Carbon 61-67 carbon/nitrogen insensitive 1 Arabidopsis thaliana 28-33 21418356-2 2011 In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation. Carbon 74-75 Cytochrome P450 superfamily protein Arabidopsis thaliana 204-212 21418356-2 2011 In Arabidopsis thaliana, bioactive brassinosteroids such as castasterone (CS) and brassinolide (BL) are inactivated mainly by two cytochrome P450 monooxygenases, CYP734A1/BAS1 and CYP72C1/SOB7/CHI2/SHK1; CYP734A1/BAS1 inactivates CS and BL by means of C-26 hydroxylation. Carbon 74-75 Cytochrome P450 superfamily protein Arabidopsis thaliana 213-217 35401468-7 2022 This led to the identification of 10 clones that are able to utilize oligosaccharides as sole carbon sources, thanks to the production of transporters from the PTS, ABC, MFS, and SusCD families. Carbon 94-100 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 165-168 21314829-0 2011 The influence of carbon content on cyclic fatigue of NiTi SMA wires. Carbon 17-23 survival of motor neuron 1, telomeric Homo sapiens 58-61 35401590-9 2022 These results are consistent with a role for SDP1 in turning over TAG to supply carbon for other needs, including the synthesis of oligosaccharides, and offer new strategies to further improve the composition of soybean seeds. Carbon 80-86 Patatin-like phospholipase family protein Arabidopsis thaliana 45-49 20827713-5 2011 Besides the ability to improve the mechanical strength and osteoconductivity of polymeric scaffolds, both carbon nanotubes (CNTs) and microhydroxyapatite (microHA) have been described to facilitate such retention of BMP-2 when incorporated into a composite scaffold. Carbon 106-112 bone morphogenetic protein 2 Rattus norvegicus 216-221 35391721-6 2022 The picophytoplankton size-fractionated chlorophyll a (Pico-Chl a) accounted for about 30% of the total Chl a, with Prochlorococcus and picoeukaryotes contributing 41 and 35%, respectively, of the Pico-Chl a-normalized carbon biomass, indicating the ecological importance of picophytoplankton as the primary producers. Carbon 219-225 chordin like 1 Homo sapiens 60-63 35051577-5 2022 To our best knowledge, there have been no reports thus far that the stereochemistry of one carbon center on the agonist structure regulates the orexin receptor selectivity. Carbon 91-97 hypocretin neuropeptide precursor Homo sapiens 144-150 21487632-2 2011 A DFT computational investigation of the catalytic mechanism of O-GlcNAcase shows the existence of a substrate-assisted reaction pathway similar to that proposed in the literature on the basis of experimental evidence: the carbonyl oxygen of the N-acyl group bonded at C2 of the substrate pyranose ring attacks the anomeric carbon affording a bicyclic oxazoline intermediate and causing the breaking of the glycosidic bond and the expulsion of the aglycon. Carbon 223-229 O-GlcNAcase Homo sapiens 64-75 35051814-1 2022 In this study, Cu-Fe bimetallic magnetic chitosan carbon aerogel catalyst (Cu-Fe@CS) was prepared by the sol-gel method to degrade Fulvic acid (FA) in Fenton-like system. Carbon 50-56 citrate synthase Homo sapiens 81-83 21754349-1 2011 Facile ligand substitution is observed when the ruthenium chloride complex [Ru(eta(5)-C(9)H(7))Cl(PPh(3))(2)] is treated with 1,4-bis-(diphenyl-phosphan-yl)butane in refluxing toluene yielding the title compound, [Ru(C(9)H(7))Cl(C(28)H(28)P(2))]. Carbon 86-87 endothelin receptor type A Homo sapiens 79-82 35243579-3 2022 The long-term elasticities of economic growth and carbon emission estimated by AMG, CCEMG, and MG estimators indicate that both clean and non-clean energy consumption has a significant impact on economic growth, while carbon emission hinders growth. Carbon 50-56 amelogenin X-linked Homo sapiens 79-82 35269071-1 2022 Double strap lap adhesive joints between metal (AA 6061-T6) and composite (carbon/epoxy) laminates were fabricated and characterized based on strength. Carbon 75-81 serine/threonine kinase receptor associated protein Homo sapiens 7-12 21527629-1 2011 Leakiness (Phi), the proportion of carbon fixed by phosphoenolpyruvate carboxylation that leaks out of the bundle-sheath cells, determines C(4) photosynthetic efficiency. Carbon 35-41 glucose-6-phosphate isomerase Homo sapiens 11-14 35098640-4 2022 A porous carbon particles cathode prepared in the presence of KOH (KCP-800) shows a high specific surface area (1326.8 m2 g-1 ), contributing to high PF6 - (de)adsorb capacity of 103.0 mA h g-1 at 1 A g-1 . Carbon 9-15 sperm associated antigen 17 Homo sapiens 150-153 35431397-5 2022 A combined experimental and computational mechanistic study has revealed that the gold catalyst has a greater affinity to the indole than the alkyne, despite the carbon-carbon bond formation step proceeding through an eta2(pi)-alkyne complex, which helps to explain the stark differences between the intra- and intermolecular variants of the reaction. Carbon 162-168 DNA polymerase iota Homo sapiens 218-222 22032081-7 2011 The use of LBS as carbon source showed higher yield of product (Yp/s), 0.59 g g-1 compared to YPD, 0.25 g g-1 in ST1 and (Yp/s), 0.54 g g-1 compared to YPD, 0.24 g g-1 in ST3 . Carbon 18-24 high affinity sulfate transporter type 1 Solanum tuberosum 113-116 35431397-5 2022 A combined experimental and computational mechanistic study has revealed that the gold catalyst has a greater affinity to the indole than the alkyne, despite the carbon-carbon bond formation step proceeding through an eta2(pi)-alkyne complex, which helps to explain the stark differences between the intra- and intermolecular variants of the reaction. Carbon 169-175 DNA polymerase iota Homo sapiens 218-222 35142483-4 2022 The sensor was fabricated via a simple and facile approach using the cold atmospheric plasma technique in which a pH sensitive silica coating was deposited from a siloxane precursor onto a carbon electrode. Carbon 189-195 phenylalanine hydroxylase Homo sapiens 114-116 35142489-2 2022 A new phosphate family member, Zn2Fe(PO4)2 (ZFP), was successfully explored and synthesized by the scalable high-temperature annealing method, followed by coating a thin carbon layer to optimize the electrotonic conductivity. Carbon 170-176 ERC2 intronic transcript 1 Homo sapiens 31-42 35203701-5 2022 The LL-37/poly I:C-induced upregulation of TLR3 mRNA expression was prevented by the endosomal acidification inhibitor chloroquine, indicating involvement of downstream TLR3 signaling. Carbon 17-18 toll like receptor 3 Homo sapiens 43-47 35203701-5 2022 The LL-37/poly I:C-induced upregulation of TLR3 mRNA expression was prevented by the endosomal acidification inhibitor chloroquine, indicating involvement of downstream TLR3 signaling. Carbon 17-18 toll like receptor 3 Homo sapiens 169-173 35049299-5 2022 In this article, we report the conformer-dependent simulated electronic absorption spectra of two four-carbon-centered Criegee intermediates, methyl vinyl ketone oxide (MVK-oxide) and methacrolein oxide (MACR-oxide). Carbon 103-109 mevalonate kinase Homo sapiens 169-172 35109908-8 2022 LINC00461 was inversely correlated with the survival of mice-bearing GBM and it was stabilized by the interaction between HDAC6 and RNA-binding proteins (RBPs) such as carbon catabolite repression-negative on TATA-less (CCR4-NOT) core exoribonuclease subunit 6 and fused in sarcoma. Carbon 168-174 long intergenic non-protein coding RNA 461 Homo sapiens 0-9 21324323-1 2011 AIMS: Folate coenzymes and dependent enzymes introduce one carbon units at positions 2 (C(2)) and 8 (C(8)) of the purine ring during de novo biosynthesis. Carbon 59-65 homeobox C8 Homo sapiens 101-105 34600402-4 2022 For this purpose, maltose binding protein harbouring the aD region (MBP-aD) was synthesized as a bioreceptor and immobilized on the screen-printed carbon electrode (SPCE). Carbon 147-153 myelin basic protein Homo sapiens 68-71 35194203-5 2022 Using carbon-11 radiotracer, we show that a maize sucrose transporter1 (sut1) loss-of-function mutant has severely reduced export of carbon from photosynthetic leaves (only ~4% of the wild type level). Carbon 6-12 sucrose transporter 1 Zea mays 50-70 21384854-2 2011 Careful optimization of the supported carbon clusters, C(N) (with size N ranging from 1 to 24), on the Ni(111) surface indicates a ground state structure transformation from a one-dimensional C chain to a 2D sp(2) C network at N 10-12. Carbon 38-44 ataxin 2 like Homo sapiens 203-207 35194203-5 2022 Using carbon-11 radiotracer, we show that a maize sucrose transporter1 (sut1) loss-of-function mutant has severely reduced export of carbon from photosynthetic leaves (only ~4% of the wild type level). Carbon 6-12 sucrose transporter 1 Zea mays 72-76 35194203-5 2022 Using carbon-11 radiotracer, we show that a maize sucrose transporter1 (sut1) loss-of-function mutant has severely reduced export of carbon from photosynthetic leaves (only ~4% of the wild type level). Carbon 133-139 sucrose transporter 1 Zea mays 50-70 35194203-5 2022 Using carbon-11 radiotracer, we show that a maize sucrose transporter1 (sut1) loss-of-function mutant has severely reduced export of carbon from photosynthetic leaves (only ~4% of the wild type level). Carbon 133-139 sucrose transporter 1 Zea mays 72-76 21384854-2 2011 Careful optimization of the supported carbon clusters, C(N) (with size N ranging from 1 to 24), on the Ni(111) surface indicates a ground state structure transformation from a one-dimensional C chain to a 2D sp(2) C network at N 10-12. Carbon 0-1 ataxin 2 like Homo sapiens 203-207 35110760-1 2022 The flow of water in carbon nanochannels has defied understanding thus far1, with accumulating experimental evidence for ultra-low friction, exceptionally high water flow rates and curvature-dependent hydrodynamic slippage2-5. Carbon 21-27 fatty acyl-CoA reductase 1 Homo sapiens 71-75 21325438-2 2011 Genetic studies in lower eukaryotes suggest that the ancestral role of AMPK was in response to starvation for a carbon source and that AMPK is involved in life-span extension in response to caloric restriction. Carbon 112-118 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 71-75 35056878-0 2022 Nucleotide Analogues Bearing a C2" or C3"-Stereogenic All-Carbon Quaternary Center as SARS-CoV-2 RdRp Inhibitors. Carbon 58-64 ORF1a polyprotein;ORF1ab polyprotein Severe acute respiratory syndrome coronavirus 2 97-101 21309792-5 2011 Carbon partitioning at ambient [CO2] was altered only in the spsa1 null mutant. Carbon 0-6 sucrose phosphate synthase 1F Arabidopsis thaliana 61-66 35062637-0 2022 Diamine Oxidase-Conjugated Multiwalled Carbon Nanotubes to Facilitate Electrode Surface Homogeneity. Carbon 39-45 amine oxidase copper containing 1 Homo sapiens 0-15 21293820-4 2011 However, when the ruthenium center is eta(6)-coordinated to a phenyl substituent linked in para-position to the carbon-to-platinum bond, i.e. complex [4](+), the SO(2)-binding property of the NCN-platinum center seems to be retained, as bubbling SO(2) into a solution of the latter complex produces the characteristic orange color. Carbon 112-118 endothelin receptor type A Homo sapiens 38-41 21143198-6 2011 Furthermore, both Pho87 and Pho90 are also targeted to the vacuole upon carbon-source starvation or upon treatment with rapamycin, which mimics nitrogen starvation, but although these responses are independent of PHO pathway signalling, they again require the N-terminal SPX domain of the transporters. Carbon 72-78 SPX domain-containing inorganic phosphate transporter Saccharomyces cerevisiae S288C 18-23 21143198-6 2011 Furthermore, both Pho87 and Pho90 are also targeted to the vacuole upon carbon-source starvation or upon treatment with rapamycin, which mimics nitrogen starvation, but although these responses are independent of PHO pathway signalling, they again require the N-terminal SPX domain of the transporters. Carbon 72-78 SPX domain-containing inorganic phosphate transporter Saccharomyces cerevisiae S288C 28-33 21262957-0 2011 AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia. Carbon 75-81 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 0-4 21145225-1 2011 An electrodeposition method was applied to form gold-platinum (AuPt) alloy nanoparticles on the glassy carbon electrode (GCE) modified with a mixture of an ionic liquid (IL) and chitosan (Ch) (AuPt-Ch-IL/GCE). Carbon 103-109 glycine cleavage system protein H Homo sapiens 121-124 21343675-1 2011 We previously showed that carbon ion irradiation can inhibit the expression of the anillin (ANLN) gene, which is regulated by the activation of the phosphatidylinositol-3-kinase (PI3K)/Akt signaling pathway associated with metastasis. Carbon 26-32 anillin, actin binding protein Homo sapiens 83-90 21343675-1 2011 We previously showed that carbon ion irradiation can inhibit the expression of the anillin (ANLN) gene, which is regulated by the activation of the phosphatidylinositol-3-kinase (PI3K)/Akt signaling pathway associated with metastasis. Carbon 26-32 anillin, actin binding protein Homo sapiens 92-96 21343675-4 2011 We found that carbon ion irradiation reduced the nuclear localization of ANLN at lower dose, but did not affect its expression. Carbon 14-20 anillin, actin binding protein Homo sapiens 73-77 21094256-8 2011 For molecules capable of direct or conjugate additions, the results suggest for the first time that TRPA1 may be activated preferentially by direct addition of the thiol group of TRPA1 cysteines to the agonist carbonyl carbon of alpha,beta-unsaturated carbonyl-containing compounds. Carbon 210-216 transient receptor potential cation channel subfamily A member 1 Homo sapiens 100-105 21094256-8 2011 For molecules capable of direct or conjugate additions, the results suggest for the first time that TRPA1 may be activated preferentially by direct addition of the thiol group of TRPA1 cysteines to the agonist carbonyl carbon of alpha,beta-unsaturated carbonyl-containing compounds. Carbon 210-216 transient receptor potential cation channel subfamily A member 1 Homo sapiens 179-184 21931597-10 2011 Based on these studies we hypothesize that, in S. oneidensis MR-1, the global BarA/UvrY/Csr regulatory pathway is involved in central carbon metabolism processes. Carbon 134-140 UvrY/SirA/GacA family response regulator transcription factor Shewanella oneidensis MR-1 83-87 22164023-5 2011 Among the selected indices, the relative distribution of PLF to the total fluorescence area of SFS (Index II) exhibited the highest correlation coefficient with total organic carbon (TOC)-based biodegradability, which was even higher than those obtained with the traditional oxygen demand-based parameters. Carbon 175-181 PLF Homo sapiens 57-60 20813456-1 2010 Batch experiments were conducted to determine the effects of metal loading and fixing methods on the capacity of granular activated carbon (GAC) for removing cyanide from KCN (pH 11), K(3)Fe(CN)(6) solutions and several SCP effluent samples. Carbon 132-138 urocortin 3 Homo sapiens 220-223 21360884-7 2010 When COD/N were 6-7, it can meet the requirement for carbon source during aerobic denitrification, the removal rate of nitrate nitrogen and COD were up to 96%, 85% respectively. Carbon 53-59 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 5-8 21360884-7 2010 When COD/N were 6-7, it can meet the requirement for carbon source during aerobic denitrification, the removal rate of nitrate nitrogen and COD were up to 96%, 85% respectively. Carbon 53-59 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 140-143 21121367-0 2010 ICAM-1 and VCAM-1 expression in rat aortic endothelial cells after single-walled carbon nanotube exposure. Carbon 81-87 vascular cell adhesion molecule 1 Rattus norvegicus 11-17 20933433-1 2010 In maize, carbonic anhydrase (CA; EC 4.2.1.1) catalyzes the first reaction of the C(4) photosynthetic pathway; it catalyzes the hydration of CO(2) to bicarbonate and provides an inorganic carbon source for the primary carboxylation reaction catalyzed by phosphoenolpyruvate (PEP) carboxylase. Carbon 10-16 carbonic anhydrase Zea mays 30-32 20688431-7 2010 TGA measurements showed a reactive carbon content of 1-2%. Carbon 35-41 T-box transcription factor 1 Homo sapiens 0-3 20471920-7 2010 The development of a novel hybrid SPR interface by the deposition of an amorphous silicon-carbon alloy is also presented. Carbon 90-96 sepiapterin reductase Homo sapiens 34-37 20863290-4 2010 We hypothesize that ACN1 recycles free acetate to acetyl-CoA within peroxisomes in order that carbon remains fed into the glyoxylate cycle. Carbon 94-100 acyl-activating enzyme 7 Arabidopsis thaliana 20-24 20863290-5 2010 When ACN1 is not present, carbon in the form of acetate can leak out of peroxisomes and is reactivated to acetyl-CoA within the cytosol. Carbon 26-32 acyl-activating enzyme 7 Arabidopsis thaliana 5-9 20863290-6 2010 Kinetic models incorporating estimates of carbon input and pathway dynamics from a variety of literature sources have proven useful in explaining how ACN1 may prevent the carbon leak and even contribute to the control of peroxisomal carbon metabolism. Carbon 42-48 acyl-activating enzyme 7 Arabidopsis thaliana 150-154 20863290-6 2010 Kinetic models incorporating estimates of carbon input and pathway dynamics from a variety of literature sources have proven useful in explaining how ACN1 may prevent the carbon leak and even contribute to the control of peroxisomal carbon metabolism. Carbon 171-177 acyl-activating enzyme 7 Arabidopsis thaliana 150-154 20863290-6 2010 Kinetic models incorporating estimates of carbon input and pathway dynamics from a variety of literature sources have proven useful in explaining how ACN1 may prevent the carbon leak and even contribute to the control of peroxisomal carbon metabolism. Carbon 171-177 acyl-activating enzyme 7 Arabidopsis thaliana 150-154 21587663-1 2010 In the title compound, C(12)H(18)NO(+) PF(6) (-), the asymmetric unit consists of two cation-anion pairs. Carbon 23-24 sperm associated antigen 17 Homo sapiens 39-44 20713697-7 2010 In response to pressure overload (PO), however, increases in Nox4 expression and O(2)(-) production in mitochondria were abolished in c-Nox4(-/-) mice, and c-Nox4(-/-) mice exhibited significantly attenuated cardiac hypertrophy, interstitial fibrosis and apoptosis, and better cardiac function compared with WT mice. Carbon 50-51 NADPH oxidase 4 Mus musculus 61-65 20713697-7 2010 In response to pressure overload (PO), however, increases in Nox4 expression and O(2)(-) production in mitochondria were abolished in c-Nox4(-/-) mice, and c-Nox4(-/-) mice exhibited significantly attenuated cardiac hypertrophy, interstitial fibrosis and apoptosis, and better cardiac function compared with WT mice. Carbon 50-51 NADPH oxidase 4 Mus musculus 136-140 20713697-7 2010 In response to pressure overload (PO), however, increases in Nox4 expression and O(2)(-) production in mitochondria were abolished in c-Nox4(-/-) mice, and c-Nox4(-/-) mice exhibited significantly attenuated cardiac hypertrophy, interstitial fibrosis and apoptosis, and better cardiac function compared with WT mice. Carbon 50-51 NADPH oxidase 4 Mus musculus 136-140 20713697-8 2010 Mitochondrial swelling, cytochrome c release, and decreases in both mitochondrial DNA and aconitase activity in response to PO were attenuated in c-Nox4(-/-) mice. Carbon 4-5 NADPH oxidase 4 Mus musculus 148-152 21588738-1 2010 The asymmetric unit of the title salt, C(5)H(6)BrN(2) (+) C(7)H(5)O(6)S(-), contains two independent 2-amino-5-bromo-pyridinium cations and two independent 3-carb-oxy-4-hy-droxy-benzene-sulfonate anions. Carbon 39-40 syntaxin 8 Homo sapiens 158-162 19846352-1 2010 A carbon-coated nickel magnetic nanoparticles modified glassy carbon electrode (C-Ni/GCE) was fabricated. Carbon 2-8 5'-nucleotidase, cytosolic IA Homo sapiens 80-88 19846352-1 2010 A carbon-coated nickel magnetic nanoparticles modified glassy carbon electrode (C-Ni/GCE) was fabricated. Carbon 62-68 5'-nucleotidase, cytosolic IA Homo sapiens 80-88 20596600-7 2010 Equally spaced carbon atoms in COMT-resistant structure 7 give more stable conformation and lower docked free energy than other EGCG analogs. Carbon 15-21 catechol-O-methyltransferase Homo sapiens 31-35 20384299-10 2010 The glucose is electrooxidized through catalysis by a glucose dehydrogenase (GDH) and an Os(2+/3+) redox mediator, which is reduced by the glucose-reduced enzyme and is electrooxidized on the carbon electrode. Carbon 192-198 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 54-75 20384299-10 2010 The glucose is electrooxidized through catalysis by a glucose dehydrogenase (GDH) and an Os(2+/3+) redox mediator, which is reduced by the glucose-reduced enzyme and is electrooxidized on the carbon electrode. Carbon 192-198 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 77-80 20416883-1 2010 Two types of activated carbons from tyre char (with or without sulphuric acid treatment) were produced via carbon dioxide activation with BET surface areas in the range 59-1118 m(2)/g. Carbon 23-30 delta/notch like EGF repeat containing Homo sapiens 138-141 20618965-4 2010 In support of the hypothesis that SIN3 is necessary for normal mitochondrial function, yeast sin3 null mutants exhibit very poor growth on non-fermentable carbon sources and show lower levels of ATP and reduced respiration rates. Carbon 155-161 transcriptional regulator SIN3 Saccharomyces cerevisiae S288C 34-38 20618965-4 2010 In support of the hypothesis that SIN3 is necessary for normal mitochondrial function, yeast sin3 null mutants exhibit very poor growth on non-fermentable carbon sources and show lower levels of ATP and reduced respiration rates. Carbon 155-161 transcriptional regulator SIN3 Saccharomyces cerevisiae S288C 93-97 20545859-6 2010 Here we report that the mutant strain with only SIP1 expressed (sip2Delta gal83Delta) could utilize acetate, but neither ethanol nor glycerol, as alternative carbon source. Carbon 158-164 Sip1p Saccharomyces cerevisiae S288C 48-52 20202172-4 2010 However FUM2 is required for the massive accumulation of carbon into fumarate that occurs in Arabidopsis leaves during the day. Carbon 57-63 FUMARASE 2 Arabidopsis thaliana 8-12 20431207-0 2010 H(2) sensing characteristics of SnO(2) coated single wall carbon nanotube network sensors. Carbon 58-64 strawberry notch homolog 1 Homo sapiens 32-35 20185144-2 2010 The high BET specific surface area (798 m(2)/g), uniform mesopore-size distribution with a median pore size of 62.6 A, and large pore volume (0.87 cm(3)/g) make the ordered mesoporous carbon an ideal adsorbent for gas separation and purification applications. Carbon 184-190 delta/notch like EGF repeat containing Homo sapiens 9-12 20136727-4 2010 Whereas single atg12a and atg12b mutants lack phenotypic consequences, atg12a atg12b double mutants senesce prematurely, are hypersensitive to nitrogen and fixed carbon starvation, and fail to accumulate autophagic bodies in the vacuole. Carbon 162-168 Ubiquitin-like superfamily protein Arabidopsis thaliana 78-84 20138775-5 2010 Here we demonstrate that ACX4 activity increases during sucrose starvation, indicating a shift to a catabolic breakdown of fatty acids as a source of available carbon. Carbon 160-166 acyl-CoA oxidase 4 Arabidopsis thaliana 25-29 20019084-0 2010 Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin. Carbon 146-152 acetolactate synthase catalytic subunit Saccharomyces cerevisiae S288C 104-108 20019084-13 2010 albicans ilv1Delta and ilv2 Delta viability was influenced by the carbon source present during starvation, supporting a role for glucose wasting in the Ca. Carbon 66-72 acetolactate synthase catalytic subunit Saccharomyces cerevisiae S288C 23-27 20080816-8 2010 When carbon nutrients are limited, gain or loss of function of AtbZIP1 causes changes in the rates of early seedling establishment. Carbon 5-11 basic leucine-zipper 1 Arabidopsis thaliana 63-70 20369570-3 2010 The MIEX addition during coagulation with both PAC1 and PACS considerably enhanced removal of dissolved organic carbon. Carbon 112-118 dual specificity phosphatase 2 Homo sapiens 47-51 20126772-7 2010 We propose that these nanographenes provide plausible building-blocks for the structure of the carbon layers formed by electron irradiation of BPT-SAMs. Carbon 95-101 methionine adenosyltransferase 1A Homo sapiens 147-151 20305775-0 2010 Formation of silicon-carbon bonds by photochemical irradiation of (eta-C(5)H(5))Fe(CO)(2)SiR(3) and (eta-C(5)H(5))Fe(CO)(2)Me to obtain R(3)SiMe. Carbon 21-27 endothelin receptor type A Homo sapiens 67-70 20305775-0 2010 Formation of silicon-carbon bonds by photochemical irradiation of (eta-C(5)H(5))Fe(CO)(2)SiR(3) and (eta-C(5)H(5))Fe(CO)(2)Me to obtain R(3)SiMe. Carbon 21-27 endothelin receptor type A Homo sapiens 101-104 19782470-5 2010 The effluents were nitrate-free and very low COD concentrations were obtained in 4-6h reaction time, especially with the sugar-rich carbon sources. Carbon 132-138 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 45-48 19782470-8 2010 The optimum COD/N ratios varied between 4.6 for the lactic acid-rich carbon source and 5.5-6.5 for the sugar-rich carbon sources. Carbon 69-75 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 12-15 19782470-8 2010 The optimum COD/N ratios varied between 4.6 for the lactic acid-rich carbon source and 5.5-6.5 for the sugar-rich carbon sources. Carbon 114-120 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 12-15 19783364-0 2010 Reduction of COD in refinery wastewater through adsorption on date-pit activated carbon. Carbon 81-87 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 13-16 19783364-1 2010 Experiments were carried out to evaluate the batch adsorption of COD from petroleum refinery wastewater on a locally prepared date-pit activated carbon (DP-AC), and its adsorption effectiveness was compared to that of commercially available BDH activated carbon (BDH-AC). Carbon 145-151 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 65-68 20000481-3 2010 The M = 13 GS of Fe(6)-(C(6)H(6))(4) shows a more distorted geometry with three eta(6) and one eta(2) coordinations, as the bonding with the fourth benzene was reduced to two C-Fe bonds. Carbon 24-25 endothelin receptor type A Homo sapiens 80-83 20000481-3 2010 The M = 13 GS of Fe(6)-(C(6)H(6))(4) shows a more distorted geometry with three eta(6) and one eta(2) coordinations, as the bonding with the fourth benzene was reduced to two C-Fe bonds. Carbon 24-25 endothelin receptor type A Homo sapiens 95-98 19539462-4 2010 An observed tendency was that the activated carbons showed high adsorption ratio, and that the adsorption ratio was increased when BET surface area was higher, and the pore volume was higher and the pH value was higher. Carbon 44-51 delta/notch like EGF repeat containing Homo sapiens 131-134 19824652-1 2009 Photochemical properties of alpha-cleavage of the C-S bond in excited states of p-biphenyl thioacetate and p-biphenyl thiobenzoate (Me-SBP and Ph-SBP) in solution are investigated using steady-state and laser flash photolyses in comparison with those of S-phenyl thiobenzoate, where the photo-Fries rearrangement was reported to be absent. Carbon 50-51 selenium binding protein 1 Homo sapiens 135-138 19824652-1 2009 Photochemical properties of alpha-cleavage of the C-S bond in excited states of p-biphenyl thioacetate and p-biphenyl thiobenzoate (Me-SBP and Ph-SBP) in solution are investigated using steady-state and laser flash photolyses in comparison with those of S-phenyl thiobenzoate, where the photo-Fries rearrangement was reported to be absent. Carbon 50-51 selenium binding protein 1 Homo sapiens 146-149 19824652-5 2009 Triplet sensitization of Ph-SBP using xanthone (XT) as a sensitizer shows that the lowest triplet (T(1)) state of Ph-SBP is dissociative for the C-S bond with an efficiency of >or.56. Carbon 145-146 selenium binding protein 1 Homo sapiens 28-31 19824652-5 2009 Triplet sensitization of Ph-SBP using xanthone (XT) as a sensitizer shows that the lowest triplet (T(1)) state of Ph-SBP is dissociative for the C-S bond with an efficiency of >or.56. Carbon 145-146 selenium binding protein 1 Homo sapiens 117-120 19824652-9 2009 This observation indicates the C-S bond cleavage in a highly excited triplet (T(n)) state of Me-SBP. Carbon 31-32 selenium binding protein 1 Homo sapiens 96-99 19908905-1 2009 This paper describes a batch-type coulometric d-fructose biosensor based on direct electron transfer reaction of d-fructose dehydrogenase (FDH) adsorbed on a porous carbon electrode surface. Carbon 165-171 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 113-137 19908905-1 2009 This paper describes a batch-type coulometric d-fructose biosensor based on direct electron transfer reaction of d-fructose dehydrogenase (FDH) adsorbed on a porous carbon electrode surface. Carbon 165-171 alcohol dehydrogenase 5 (class III), chi polypeptide Homo sapiens 139-142 19782385-5 2009 The carbon contents increased from 43.34% to 51.90% and 43.06% to 53.26% while the oxygen contents decreased from 46.39% to 36.76% and 49.76% to 40.03% for PF1-PF4 and NF1-NF4, respectively. Carbon 4-10 PHD finger protein 12 Homo sapiens 156-163 21578527-2 2009 One- and two-dimensional (1)H and (13)C NMR spectra, as well as IR data, are in agreement with the presence of a ketoxime group at C-23. Carbon 38-39 nucleolin Homo sapiens 131-135 19501959-9 2009 Acid Red 2 by electrooxidation is due to the partial or complete cleavage of C-N bonds in C.I. Carbon 77-78 adenosine deaminase RNA specific B2 (inactive) Homo sapiens 5-10 19673520-3 2009 Here we provide the first demonstration that bovine submaxillary mucin and porcine gastric mucin accelerate the rate of fatty acid p-nitrophenol ester hydrolysis up to 337 times and a carbon-carbon bond-forming Diels-Alder reaction between N-propylmaleimide and anthracene up to 200 times relative to the rates of the reference processes, which were performed in water and chloroform, respectively. Carbon 184-190 mucin 1, cell surface associated Bos taurus 65-70 19673520-3 2009 Here we provide the first demonstration that bovine submaxillary mucin and porcine gastric mucin accelerate the rate of fatty acid p-nitrophenol ester hydrolysis up to 337 times and a carbon-carbon bond-forming Diels-Alder reaction between N-propylmaleimide and anthracene up to 200 times relative to the rates of the reference processes, which were performed in water and chloroform, respectively. Carbon 184-190 mucin 1, cell surface associated Bos taurus 91-96 19673520-3 2009 Here we provide the first demonstration that bovine submaxillary mucin and porcine gastric mucin accelerate the rate of fatty acid p-nitrophenol ester hydrolysis up to 337 times and a carbon-carbon bond-forming Diels-Alder reaction between N-propylmaleimide and anthracene up to 200 times relative to the rates of the reference processes, which were performed in water and chloroform, respectively. Carbon 191-197 mucin 1, cell surface associated Bos taurus 65-70 19673520-3 2009 Here we provide the first demonstration that bovine submaxillary mucin and porcine gastric mucin accelerate the rate of fatty acid p-nitrophenol ester hydrolysis up to 337 times and a carbon-carbon bond-forming Diels-Alder reaction between N-propylmaleimide and anthracene up to 200 times relative to the rates of the reference processes, which were performed in water and chloroform, respectively. Carbon 191-197 mucin 1, cell surface associated Bos taurus 91-96 19634897-11 2009 The second, persistent radical is more stable than the transient species and is assigned as a tautomer, in which a C6(H) of the transient radical is transferred to the carboxaldehyde carbon (C4") of PLP. Carbon 183-189 pyridoxal phosphatase Homo sapiens 199-202 19387639-1 2009 PURPOSE: [(11)C]Acetate (C-AC) is a general PET tracer of cellular carbon flux and useful for clinical imaging in heart disease as well as prostate cancer and other tumours. Carbon 67-73 solute carrier family 25 member 20 Homo sapiens 25-29 19563425-2 2009 One technological approach to control carbon dioxide emissions is carbon capture and storage, or CCS. Carbon 38-44 copper chaperone for superoxide dismutase Homo sapiens 97-100 19563425-3 2009 The underlying idea of CCS is to capture the carbon before it emitted to the atmosphere and store it somewhere other than the atmosphere. Carbon 45-51 copper chaperone for superoxide dismutase Homo sapiens 23-26 19666527-6 2009 Reactant and product structures establish reaction coordinate motion for NAMPT to be migration of the ribosyl anomeric carbon from the pyrophosphate leaving group to the nicotinamide-N1 while the 5-phosphoryl group, the pyrophosphate moiety, and the nicotinamide ring remain fixed in the catalytic site. Carbon 119-125 nicotinamide phosphoribosyltransferase Homo sapiens 73-78 19181445-7 2009 The proper choice of preparation conditions resulted in a microporous activated carbon with 0.45 g/cm(3) density, 737 mg/g iodine number and 780 m(2)/g BET surface area. Carbon 80-86 delta/notch like EGF repeat containing Homo sapiens 152-155 19635904-2 2009 Polyinosinic-polycytidylic acid (poly I:C), a double-stranded RNA analog recognized by melanoma-differentiation associated gene 5 (MDA5) and TLR3, activates NK cells in vivo. Carbon 40-41 toll like receptor 3 Homo sapiens 141-145 19652318-2 2009 In the case of (I), the long distance between the O atom of the carbonyl group and the gamma-H atom, and between the C atom of the carbonyl group and the gamma-C atom, preclude Yang photocyclization. Carbon 117-118 interleukin 2 receptor subunit gamma Homo sapiens 154-161 19916425-2 2009 Characterization of the carbon thus obtained was performed by N2 adsorption isotherms (BET surface area), temperature programmed desorption (TPD), temperature programmed oxidation (TPO), X-ray diffraction, Raman spectrometry, and electron microscopy SEM and TEM. Carbon 24-30 delta/notch like EGF repeat containing Homo sapiens 87-90 2584212-1 1989 The dihydrofolate reductase gene encodes a key enzyme of one-carbon metabolism and is constitutively expressed in all cells. Carbon 61-67 dihydrofolate reductase Homo sapiens 4-27 19499593-8 2009 In contrast, a structure determination of a human O-GlcNAcase homologue bound to a related inhibitor N-butyryl-PUGNAc, which bears a four-carbon chain and is selective for both NagZ and O-GlcNAcase over the human beta-hexosamnidases, reveals that this inhibitor induces several conformational changes in the active site of this O-GlcNAcase homologue. Carbon 138-144 O-GlcNAcase Homo sapiens 50-61 19499593-8 2009 In contrast, a structure determination of a human O-GlcNAcase homologue bound to a related inhibitor N-butyryl-PUGNAc, which bears a four-carbon chain and is selective for both NagZ and O-GlcNAcase over the human beta-hexosamnidases, reveals that this inhibitor induces several conformational changes in the active site of this O-GlcNAcase homologue. Carbon 138-144 O-GlcNAcase Homo sapiens 186-197 19499593-8 2009 In contrast, a structure determination of a human O-GlcNAcase homologue bound to a related inhibitor N-butyryl-PUGNAc, which bears a four-carbon chain and is selective for both NagZ and O-GlcNAcase over the human beta-hexosamnidases, reveals that this inhibitor induces several conformational changes in the active site of this O-GlcNAcase homologue. Carbon 138-144 O-GlcNAcase Homo sapiens 186-197 19450265-1 2009 BACKGROUND: The catabolite control protein A (CcpA) is a member of the LacI/GalR family of transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram-positive bacteria. Carbon 130-136 AT695_RS08815 Staphylococcus aureus 16-44 19450265-1 2009 BACKGROUND: The catabolite control protein A (CcpA) is a member of the LacI/GalR family of transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram-positive bacteria. Carbon 130-136 AT695_RS08815 Staphylococcus aureus 46-50 19264317-1 2009 The bonding kinetics for 10 A Z-Tetraol films on the amorphous nitrogenated carbon surface (CNx) is investigated as a function of the Z-Tetraol molecular polarity. Carbon 76-82 calnexin Homo sapiens 92-95 19420643-1 2009 A metal sulfide such as ZnS, CdS, Ag(2)S or PbS was coated on the sidewall of multiwalled carbon nanotubes (MWCNTs) by an in situ wet chemical synthesis approach via noncovalent functionalization of MWCNTs with a polyelectrolyte (polyethylenimine or poly(diallyldimethylammonium chloride)) without causing significant electronic and structural modification of the carbon nanotubes. Carbon 90-96 angiotensin II receptor type 1 Homo sapiens 34-40 19452017-11 2009 Similarly, the poly(I:C)-induced activation of NFkappaB was decreased by both DEX and CsA, and the activation of IRF3 was reduced by DEX alone. Carbon 22-23 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 86-89 19391633-3 2009 In complex 1, the DAB(2-) ligand is bonded to the metal center via two covalent YN bonds, while in complexes 2 and 3 additional eta(2)-coordination of the C=C bond to the metal atom is observed, both in solution and in the solid state. Carbon 155-156 DAB adaptor protein 2 Homo sapiens 18-25 19391633-3 2009 In complex 1, the DAB(2-) ligand is bonded to the metal center via two covalent YN bonds, while in complexes 2 and 3 additional eta(2)-coordination of the C=C bond to the metal atom is observed, both in solution and in the solid state. Carbon 157-158 DAB adaptor protein 2 Homo sapiens 18-25 19534162-5 2009 The activated carbon prepared under vacuum exhibited higher values of the BET surface area (up to 1079 m2 g(-1)) and total pore volume (up to 0.5665 cm3 g(-1)) than those of the activated carbon obtained under atmosphere. Carbon 14-20 delta/notch like EGF repeat containing Homo sapiens 74-77 19268474-2 2009 Using site-selectively incorporated carbon-deuterium bonds, we show that like the equine protein, bovine cytochrome c is induced to unfold by guanidine hydrochloride via a stepwise mechanism, but it does not populate an intermediate as is observed with the equine protein. Carbon 36-42 LOC104968582 Bos taurus 105-117 19039788-3 2009 Here we demonstrate the morphological plasticity of tkt deficient strain of Bacillus pumilus ATCC 21951 and its possible relation with D-ribose productivity, a measure of carbon flux through PPP. Carbon 171-177 AKO65_RS14630 Bacillus pumilus 52-55 19496481-4 2009 Using factor analysis, a group of elements consistent with a mobile combustion source (carbon monoxide, nitrogen dioxide, elemental and organic carbon) was significantly associated with total mortality (RR 1.11; 95% CI = 1.083-1.138). Carbon 87-93 ribonucleotide reductase catalytic subunit M1 Homo sapiens 203-207 19259639-3 2009 Elovl6 is a microsomal enzyme involved in the elongation of saturated and monounsaturated fatty acids with 12, 14, and 16 carbons. Carbon 122-129 ELOVL family member 6, elongation of long chain fatty acids (yeast) Mus musculus 0-6 19124153-4 2009 We found that nitrogen-doped diamond-like carbon (DLC:N) promoted cell attachment relative to other materials tested in the rank order of DLC:N>In(2)O(3)/SnO(2) (ITO), Pt>Au. Carbon 42-48 strawberry notch homolog 1 Homo sapiens 157-160 19137564-6 2009 An electron donor-electron acceptor (EDA) mechanism between the carbon of CO(2) and the nitrogen of the heterocycle and weak hydrogen bonds stabilize the complex, with important contributions from dispersion and induction forces. Carbon 64-70 ectodysplasin A Homo sapiens 37-40 19084825-2 2009 Further increase in solution pH results in the deprotonation of OH-groups adjacent to C-2 and C-3 carbon atoms of beta-CD glucopyranose units, whereas the deprotonation of OH-groups adjacent to C-6 carbon atoms is expressed less markedly. Carbon 198-204 complement C6 Homo sapiens 194-197 19139398-5 2009 The importance of the dau operon in D-arginine metabolism was demonstrated by the findings that strains with a lesion at dauA or dauB failed to use D-arginine as sole carbon source. Carbon 167-173 NAD(P)H-dependent anabolic L-arginine dehydrogenase DauB Pseudomonas aeruginosa PAO1 129-133 19421331-7 2009 We also observed suppression of sec9 mutations by growth on alkaline media or on a non-fermentable carbon source, conditions associated with a reduced growth rate of wild-type cells and decreased SNARE complex formation. Carbon 99-105 Sec9p Saccharomyces cerevisiae S288C 32-36 2685572-4 1989 The in vivo hexokinase II activity was determined by measuring growth rates, using fructose as a carbon source. Carbon 97-103 hexokinase Saccharomyces cerevisiae S288C 12-22 22389624-4 2009 Nanomaterials including nanoparticles and nanotubes, prepared from metals, semiconductor, carbon or polymeric species, have been widely investigated for their ability to enhance the efficiencies of ECL biosensors, such as taking as modification electrode materials, or as carrier of ECL labels and ECL-emitting species. Carbon 90-96 C-C motif chemokine ligand 21 Homo sapiens 198-201 2552292-4 1989 Both NUC1 and nuc1 strains containing the L-A genome exhibited an increase in coat protein abundance and a concomitant increase in L-A dsRNA when the cells were grown on a nonfermentable carbon source rather than on glucose, an effect independent of the increase in coat protein due to nuc1 mutations or to the absence of M. The increase in L-A expression in nuc1 strains was similar to that observed in strains with mutations in the nuclear gene encoding the most abundant outer mitochondrial membrane protein, porin. Carbon 187-193 ribonuclease Saccharomyces cerevisiae S288C 5-9 2552292-4 1989 Both NUC1 and nuc1 strains containing the L-A genome exhibited an increase in coat protein abundance and a concomitant increase in L-A dsRNA when the cells were grown on a nonfermentable carbon source rather than on glucose, an effect independent of the increase in coat protein due to nuc1 mutations or to the absence of M. The increase in L-A expression in nuc1 strains was similar to that observed in strains with mutations in the nuclear gene encoding the most abundant outer mitochondrial membrane protein, porin. Carbon 187-193 ribonuclease Saccharomyces cerevisiae S288C 14-18 2568633-4 1989 Crossing of pas1-1 and pas2 strains resulted in diploid cells that had regained the ability to grow on oleic acid as sole carbon source and to form peroxisomes. Carbon 122-128 E2 ubiquitin-protein ligase peroxin 4 Saccharomyces cerevisiae S288C 23-27 19759463-1 2009 A spherical microporous carbon adsorbent (CR-1), which was developed by carbonization and activation of the waste polysulfonated cation-exchanger, was used to remove Dimethyl phthalate (DMP) and 2, 4-dichlorophenol (2, 4-DCP) as the model compounds of EDCs from the aqueous solution. Carbon 24-30 complement C3b/C4b receptor 1 (Knops blood group) Homo sapiens 42-46 2539480-7 1989 In addition, shortening the side chain by one carbon atom resulted in compounds with affinity for hippocampal 5-HT1A sites comparable to that of racemic propranolol, but with a 30- to 500-fold lower affinity for 5-HT1B sites and a greater than 1000-fold lower affinity for beta-adrenergic sites. Carbon 46-52 5-hydroxytryptamine receptor 1A Homo sapiens 110-116 18848968-6 2008 The active fraction of HESL was isolated by column chromatography and the structure of the active compound dehydrocostus lactone (DHCL) was identified via (1)H NMR and (13)C NMR. Carbon 132-133 helt bHLH transcription factor Homo sapiens 23-27 3137224-4 1988 After labeling with 14CO2, the label distribution in the glutamate molecule (95% of the label at glutamate C-1) was consistent with an input of carbon via the phosphoenolpyruvate carboxylase reaction, and the relative specific radioactivities of aspartate and glutamate permitted the quantification of the apparent rate of the fumarase reaction. Carbon 144-150 heterogeneous nuclear ribonucleoprotein C Homo sapiens 107-110 3137224-9 1988 The fraction of labeled substrate incorporated into carbohydrates was only about 5% of that converted to CO2; the carbon flux into gluconeogenesis was determined after labeling with 14CO2 and [1-14C]hexanoate from the specific radioactivity of aspartate C-1 and the amount of label incorporated into the carbohydrate fraction. Carbon 114-120 heterogeneous nuclear ribonucleoprotein C Homo sapiens 254-257 19248506-0 2008 [Raman spectra of PAN-based carbon fibers during surface treatment]. Carbon 28-34 adenosine deaminase 2 Homo sapiens 18-21 19248506-1 2008 Laser Raman spectroscopy was employed to characterize the microstructure changes of PAN based carbon fibers among different surface treatments, and the characteristics of first-order Raman spectra of carbon fibers during surface treatment were investigated in the present paper. Carbon 94-100 adenosine deaminase 2 Homo sapiens 84-87 3290644-5 1988 ADH2 was regulated by the carbon source to the same extent in all strains examined and showed complete dependence on ADR1 as well. Carbon 26-32 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 0-4 3377503-1 1988 A Mycobacterium sp., designated strain BG1, able to utilize the polycyclic aromatic hydrocarbon phenanthrene as the sole carbon and energy source was isolated from estuarine sediment following enrichment with the hydrocarbon. Carbon 89-95 acyl-CoA synthetase bubblegum family member 1 Homo sapiens 39-42 19248506-3 2008 During different surface treatment, some changes in the first-order Raman spectroscopy parameters of PAN based carbon fibers were observed, the Raman frequency shifts of D and G bands moved toward higher wavenumber, and the values of R(I(D)/I(G)) also improved, which can be used to measure the graphite crystallite size of carbon fiber. Carbon 111-117 adenosine deaminase 2 Homo sapiens 101-104 18855383-1 2008 The half-sandwich cobalt(I) complex (eta (6)-C 7H 8)CoAr*-3,5- ( i )Pr 2 (Ar*-3,5- ( i )Pr 2 = -C 6H-2,6-(C 6H 2-2,4,6- ( i )Pr 3) 2-3,5- ( i )Pr 2) was synthesized by reduction of [3,5- ( i )Pr 2Ar*Co(mu-Cl)] 2 in toluene. Carbon 45-46 endothelin receptor type A Homo sapiens 37-40 3343233-9 1988 Using the alpha-carbon coordinates of crystalline cat muscle pyruvate kinase, a length distribution profile was calculated, and it matches the scattering profile of the inactive form. Carbon 16-22 pyruvate kinase PKLR Oryctolagus cuniculus 61-76 2832732-3 1988 Like mutations in HAP2, a mutation in HAP3 abolishes the activity of UAS2 and prevents growth on nonfermentable carbon sources. Carbon 112-118 transcription activator HAP2 Saccharomyces cerevisiae S288C 18-22 2832732-3 1988 Like mutations in HAP2, a mutation in HAP3 abolishes the activity of UAS2 and prevents growth on nonfermentable carbon sources. Carbon 112-118 Hap3p Saccharomyces cerevisiae S288C 38-42 18358715-7 2008 More than 84% of Cr3+ was removed by HA2, 54% by HA3 and 51% by HA1 and 50% by AC from aqueous solution. Carbon 79-81 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 17-20 3321068-2 1987 This finding creates a paradox because apocytochrome activation by HAP2-HAP3 is highly regulated, subject to induction by heme, and subject to further derepression by a shift from glucose medium to one containing a nonfermentable carbon source. Carbon 230-236 transcription activator HAP2 Saccharomyces cerevisiae S288C 67-71 3321068-2 1987 This finding creates a paradox because apocytochrome activation by HAP2-HAP3 is highly regulated, subject to induction by heme, and subject to further derepression by a shift from glucose medium to one containing a nonfermentable carbon source. Carbon 230-236 Hap3p Saccharomyces cerevisiae S288C 72-76 18434258-3 2008 Single-stranded DNA probe specific to bar gene was covalently attached by 5"-phosphate end to the surface of carbon paste electrode. Carbon 109-115 bifunctional apoptosis regulator Homo sapiens 38-41 2832680-1 1987 SRI 62-834, an analog of the antitumor agent ET-18-OCH3 in which the oxygen atom at carbon atom 2 has been incorporated into a five-membered heterocycle, has been prepared and evaluated as an antitumor agent. Carbon 84-90 sorcin Mus musculus 0-3 18554307-9 2008 Btn2p deletion increases the fermentative capacity of flor yeast and its overexpression prevents its growth on nonfermentable carbon sources. Carbon 126-132 Btn2p Saccharomyces cerevisiae S288C 0-5 16665405-4 1987 Carbons 1-3 of this aspartic acid are in the normal C(3) range, but carbon-4 (obtained by treatment of the aspartic acid with aspartate beta-decarboxylase) has an isotopic composition in the range expected for products of C(4) photosynthesis (-5 per thousand), and it appears that more than half of the aspartic acid is synthesized by phosphoenolpyruvate carboxylase using atmospheric CO(2)/HCO(3) (-). Carbon 68-74 phosphoenolpyruvate carboxylase Nicotiana tabacum 335-366 18689525-5 2008 The gene YlFBP1 restored fructose-1,6-bisphosphatase activity and growth in gluconeogenic carbon sources to a Saccharomyces cerevisiae fbp1 mutant, but the introduction of the FBP1 gene from S. cerevisiae in the Ylfbp1 mutant did not produce fructose-1,6-bisphosphatase activity or growth complementation. Carbon 90-96 fructose 1,6-bisphosphate 1-phosphatase Saccharomyces cerevisiae S288C 11-15 2848693-10 1987 These electroencephalographic findings suggest that DGVA, which has one more carbon in its chain than N-amidino-GABA, might act directly on the GABA-receptor to induce spike discharges and might be a specific GABA-receptor antagonist. Carbon 77-83 GABA type A receptor-associated protein Homo sapiens 144-157 18689527-4 2008 Acetyl-CoA is trafficked in the form of acetate by the carnitine shuttle, and we hypothesized that the enzymes that convert acetyl-CoA to/from acetate, i.e., acetyl-CoA hydrolase (ACH1) and acetyl-CoA synthetase (ACS1 and ACS2), would regulate alternative carbon utilization and virulence. Carbon 256-262 acetyl-CoA hydrolase Saccharomyces cerevisiae S288C 180-184 3100802-7 1987 Branching of chains at the alpha-carbon, which resulted in increased substituent thickness, was detrimental to E. coli DHFR inhibition in particular. Carbon 33-39 Dihydrofolate reductase Escherichia coli 119-123 18689527-5 2008 We show that C. albicans strains depleted for ACS2 are unviable in the presence of most carbon sources, including glucose, acetate, and ethanol; these strains metabolize only fatty acids and glycerol, a substantially more severe phenotype than that of Saccharomyces cerevisiae acs2 mutants. Carbon 88-94 acetate--CoA ligase ACS2 Saccharomyces cerevisiae S288C 46-50 18690727-7 2008 Finally, we find that E-AB signal gain is sensitive to the nature of the alkanethiol SAM employed to passivate the interrogating electrode; while thinner SAMs lead to higher absolute sensor currents, reducing the length of the SAM from 6-carbons to 2-carbons reduces the observed signal gain of our cocaine sensor 10-fold. Carbon 251-258 methionine adenosyltransferase 1A Homo sapiens 154-158 2428865-9 1986 When monocytes were induced with poly-I.C, 22-fold higher levels of interferon were produced by the cells exposed to CSF-1. Carbon 40-41 colony stimulating factor 1 Homo sapiens 117-122 18321644-6 2008 Hydroxyl radicals reacted with the azo linkage-bearing carbon of a hydroxy-substituted ring, leading to the cleavage of -C-N- and degradation of AO7. Carbon 55-61 ring finger protein 25 Homo sapiens 145-148 3743570-2 1986 The isotope in the glutamate was specifically incorporated into the eight carbon atoms in the tetrapyrrole macrocycle derived from the C-5 of 5-aminolevulinic acid, while no specific enrichment of these eight carbon atoms was observed in the spectrum of the pigment formed in the presence of [2-13C]glycine. Carbon 74-80 complement C5 Homo sapiens 135-138 18662016-0 2008 Toward a fast, easy, and versatile immobilization of biomolecules into carbon nanotube/polysulfone-based biosensors for the detection of hCG hormone. Carbon 71-77 chorionic gonadotropin subunit beta 5 Homo sapiens 137-140 3743570-6 1986 The 13C chemical shifts of two sp2 quaternary carbons of bacteriopheophorbide c methyl ester (C-2 and C-4) were reassigned. Carbon 46-53 complement C2 Homo sapiens 94-97 3743570-6 1986 The 13C chemical shifts of two sp2 quaternary carbons of bacteriopheophorbide c methyl ester (C-2 and C-4) were reassigned. Carbon 46-53 complement C4A (Rodgers blood group) Homo sapiens 102-105 3733707-8 1986 In addition, either increasing or decreasing the number of carbons of the side chain reduced the affinity of the inhibitor for cytochrome P-450 1. Carbon 59-66 cytochrome P450 2C5 Oryctolagus cuniculus 127-145 18366019-6 2008 The electron-withdrawing stabilization by various residues, involving Arg386, Tyr225, Asp222, Asn194, and peptide backbone, enhances the carbon acidity of 4"-C of PLP and Calpha of amino acid. Carbon 137-143 pyridoxal phosphatase Homo sapiens 163-166 3708089-7 1986 We analyze data obtained from dioleoylphosphatidylcholine (DOPC) bilayers at 66% RH using standard Fourier profile analyses and from DOPC deuterated specifically at the C-2 carbon of the acyl chains using difference Fourier analysis. Carbon 173-179 complement C2 Homo sapiens 169-172 3708089-8 1986 We demonstrate that strip-function models accurately define the positions of the C-2 carbons and thus the hydrocarbon thickness (dhc) of the bilayer. Carbon 85-92 complement C2 Homo sapiens 81-84 2689220-3 1989 An RNA of about 2 kb which hybridized with a DNA probe internal to the PCK1 gene was found only in cells growing in non-fermentable carbon sources. Carbon 132-138 phosphoenolpyruvate carboxykinase PCK1 Saccharomyces cerevisiae S288C 71-75 18582857-4 2008 Mediolateral cell polarization underlying C&E is regulated by a noncanonical Wnt signaling pathway constituting the vertebrate planar cell polarity (PCP) pathway. Carbon 42-43 wnt 11, family member 2 Danio rerio 81-84 2605196-3 1989 The compound (5,5,5-trifluoro-4-oxopentyl)trimethylammonium bicarbonate (1) inhibits acetylcholinesterase with Ki = 0.06 X 10(-9)M and pseudocholinesterase with Ki = 70 X 10(-9)M. Replacement of the nitrogen of 1 by carbon (compound 2) increases Ki for 1 200-fold for acetylcholinesterase but does not significantly alter Ki for pseudocholinesterase. Carbon 62-68 butyrylcholinesterase Homo sapiens 135-155 2605196-3 1989 The compound (5,5,5-trifluoro-4-oxopentyl)trimethylammonium bicarbonate (1) inhibits acetylcholinesterase with Ki = 0.06 X 10(-9)M and pseudocholinesterase with Ki = 70 X 10(-9)M. Replacement of the nitrogen of 1 by carbon (compound 2) increases Ki for 1 200-fold for acetylcholinesterase but does not significantly alter Ki for pseudocholinesterase. Carbon 62-68 butyrylcholinesterase Homo sapiens 329-349 2554526-4 1989 Response is greatly reduced with no alkyl group in position 2 of PAF and decreases progressively as the number of carbons of the alkyl gets larger than three. Carbon 114-121 PCNA clamp associated factor Homo sapiens 65-68 2676721-1 1989 The CYC1 gene of Saccharomyces cerevisiae is positively regulated by the HAP2 and HAP3 proteins, which form a heteromeric complex that binds to a CCAAT box in the upstream activation site, UAS2, and which activate transcription in a nonfermentable carbon source. Carbon 248-254 cytochrome c isoform 1 Saccharomyces cerevisiae S288C 4-8 2676721-1 1989 The CYC1 gene of Saccharomyces cerevisiae is positively regulated by the HAP2 and HAP3 proteins, which form a heteromeric complex that binds to a CCAAT box in the upstream activation site, UAS2, and which activate transcription in a nonfermentable carbon source. Carbon 248-254 transcription activator HAP2 Saccharomyces cerevisiae S288C 73-77 2676721-1 1989 The CYC1 gene of Saccharomyces cerevisiae is positively regulated by the HAP2 and HAP3 proteins, which form a heteromeric complex that binds to a CCAAT box in the upstream activation site, UAS2, and which activate transcription in a nonfermentable carbon source. Carbon 248-254 Hap3p Saccharomyces cerevisiae S288C 82-86 3954792-0 1986 Stereospecific deuterium substitution at the alpha-carbon position of dopamine and its effect on oxidative deamination catalyzed by MAO-A and MAO-B from different tissues. Carbon 51-57 monoamine oxidase A Homo sapiens 132-137 2867801-3 1985 Furthermore, SMS 201-995 administration significantly increased the plasma clearance of colloidal carbon as indicated by a lower area under the curve and an increased elimination constant. Carbon 98-104 spermine synthase Rattus norvegicus 13-16 3840372-2 1985 Upon oxygenation of phenacyl phenyl sulfide, the FAD-containing monooxygenase gave solely phenacyl phenyl sulfoxide in contrast to the cytochrome P-450 promoted oxygenation which is known to give substantial amounts of C-S bond fission products. Carbon 219-220 cytochrome P450 family 2 subfamily D member 6 Sus scrofa 135-151 3935306-5 1985 When reovirus was presented to these bacteria as a sole source of carbon, some growth (determined spectrophotometrically) of B. subtilis and S. marcescens occurred with reovirus concentrations of 3.1 X 10(6) and 8.2 X 10(6) mean tissue culture infective dose-fifty X mL-1, respectively. Carbon 66-72 L1 cell adhesion molecule Mus musculus 267-271 4044546-1 1985 Intestinal and hepatic ornithine decarboxylase (ODC) activities increased to a peak 4 h after administration of a diet containing casein or an amino acid mixture simulating that of casein to rats starved for 12 h. All amino acids except cysteine with a two or three carbon skeleton, including those with a D-configuration, and alpha-amino-isobutyric acid (AIB) strongly induced intestinal ODC when given in the diet or administered intragastrically. Carbon 266-272 ornithine decarboxylase 1 Rattus norvegicus 48-51 3967487-2 1985 The apparent Km (TG) and Km (C-II) for HM-LPL were 2.2 and 6.7-fold higher than for BM-LPL. Carbon 29-30 lipoprotein lipase Homo sapiens 42-45 3967487-2 1985 The apparent Km (TG) and Km (C-II) for HM-LPL were 2.2 and 6.7-fold higher than for BM-LPL. Carbon 29-30 lipoprotein lipase Homo sapiens 87-90 21825767-2 2008 The size of Ag(2)S nanocrystals with regular shape can be controlled in the range of tens of nanometers by adjusting critical parameters, such as the carbon number of the substitute alkyl, the solvent and the reaction temperature. Carbon 150-156 angiotensin II receptor type 1 Homo sapiens 12-18 6547959-2 1984 Paramagnetic effects of Mn2+-glyoxalase I on the longitudinal relaxation rates of the carbon-bound protons of the substrate analog S-(acetonyl)-glutathione at three frequencies, the hydrophobic competitive inhibitor S-(propyl)glutathione at four frequencies, and the charged competitive inhibitor S-(carboxymethyl)glutathione at a single frequency were used to calculate Mn2+ to proton distances in each complex. Carbon 86-92 glyoxalase I Homo sapiens 29-41 18289828-5 2008 In particular, monoalkylphenols having a 6-9 carbon alkyl group para to the phenolic hydroxyl group possessed high affinity for the RAR gamma, and their activities were 1.363-0.446% of that of all-trans RA. Carbon 45-51 retinoic acid receptor gamma Homo sapiens 132-141 6469979-7 1984 This is direct evidence for internal motion of backbone and side-chain carbons in myosin and its fragments. Carbon 71-78 myosin heavy chain 14 Homo sapiens 82-88 6469979-8 1984 Double resonance experiments at 15.1 MHz and 5 degrees C with pelleted myosin filaments detected carbon atoms in rigid domains. Carbon 97-103 myosin heavy chain 14 Homo sapiens 71-77 20641481-27 2004 As a membrane translocation module, MPAP has a hydrophobic 14-carbon moiety of myristic acid (Myr, -C(=O)-(CH2)12-CH3) linked to a polyarginine peptide to generate Myr-Ala-(Arg)7-Cys-CONH2 (17). Carbon 62-68 phospholipid phosphatase 1 Mus musculus 36-40 18451058-10 2008 However, additional phenotypic screening tests on the C. albicans mutants revealed that the presence of ASG1 was necessary to sustain growth on non-fermentative carbon sources (sodium acetate, acetic acid, ethanol). Carbon 161-167 Asg1p Saccharomyces cerevisiae S288C 104-108 18299327-4 2008 In the first we have deleted the last eight amino acids of Anc2p (Anc2pDeltaCter) and demonstrated that the C-terminal end of Anc2p plays an essential role in yeast growth on a non-fermentable carbon source. Carbon 193-199 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 59-64 6370959-17 1984 The defect in carbon catabolite repression was strongly associated with the defect in hexokinase PII and was independent of the glucose phosphorylating capacity. Carbon 14-20 hexokinase Saccharomyces cerevisiae S288C 86-96 6638174-3 1983 In contrast, when the isotopic enrichment of C-1 of glucose was measured by enzymatic decarboxylation and ratio mass spectrometry, the "apparent" glucose production including carbon recycling was obtained. Carbon 175-181 heterogeneous nuclear ribonucleoprotein C Homo sapiens 45-48 6578872-4 1983 Labeling of the carbonyl carbon (C-1) was determined by Schmidt degradation and used to distinguish between chain elongation of pre-existing cellular fatty acids and de novo synthesis. Carbon 16-22 heterogeneous nuclear ribonucleoprotein C Homo sapiens 33-36 18299327-4 2008 In the first we have deleted the last eight amino acids of Anc2p (Anc2pDeltaCter) and demonstrated that the C-terminal end of Anc2p plays an essential role in yeast growth on a non-fermentable carbon source. Carbon 193-199 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 66-71 18281401-0 2008 Sinorhizobium meliloti mutants lacking phosphotransferase system enzyme HPr or EIIA are altered in diverse processes, including carbon metabolism, cobalt requirements, and succinoglycan production. Carbon 128-134 haptoglobin-related protein Homo sapiens 72-75 6639023-1 1983 The overall growth rate of bacteria on granular activated carbon (GAC) contactors at the Philadelphia Torresdale Water Treatment Pilot Plant facility was found to decrease until steady state was reached. Carbon 58-64 glutaminase Homo sapiens 66-69 6639023-2 1983 The growth rate was found to fluctuate between 6.94 X 10(-3) and 8.68 X 10(-4) doublings per h. The microbiological removal of total organic carbon (TOC) was calculated by considering the GAC contactors as semiclosed continuous culture systems and using growth yield factors determined in laboratory experiments. Carbon 141-147 glutaminase Homo sapiens 188-191 21817675-4 2008 Our sensor showed higher sensitivity compared to different types of sensors including SnO(2) powder-based thin films, SnO(2) coating on carbon nanotubes or single/multiple SnO(2) nanobelts. Carbon 136-142 strawberry notch homolog 1 Homo sapiens 118-121 6867011-8 1983 The results suggest that structural integrity of the glucose molecule from the C-1 to C-4 carbon atoms, a free aldehyde group on the C-1 carbon atom, and a cyclic structure are all necessary for both the active transport of glucose and the release of endogenous GIP. Carbon 90-96 complement C2 Canis lupus familiaris 79-89 21817675-4 2008 Our sensor showed higher sensitivity compared to different types of sensors including SnO(2) powder-based thin films, SnO(2) coating on carbon nanotubes or single/multiple SnO(2) nanobelts. Carbon 136-142 strawberry notch homolog 1 Homo sapiens 118-121 17570583-2 2008 In this research, a spherical microporous carbon adsorbent (CR-1) had been obtained by carbonization and activation of the waste polysulfonated cation exchange resin. Carbon 42-48 complement C3b/C4b receptor 1 (Knops blood group) Homo sapiens 60-64 6853506-2 1983 glyoxalase I on the 13C relaxation rates of the reaction product, S-(D-lactoyl)glutathione, separately enriched in the lactoyl carbonyl (C-1) and hydroxymethylene (C-2) carbons, have been measured at 62.8 MHz. Carbon 169-176 glyoxalase I Homo sapiens 0-12 6853506-2 1983 glyoxalase I on the 13C relaxation rates of the reaction product, S-(D-lactoyl)glutathione, separately enriched in the lactoyl carbonyl (C-1) and hydroxymethylene (C-2) carbons, have been measured at 62.8 MHz. Carbon 169-176 heterogeneous nuclear ribonucleoprotein C Homo sapiens 137-140 6853506-2 1983 glyoxalase I on the 13C relaxation rates of the reaction product, S-(D-lactoyl)glutathione, separately enriched in the lactoyl carbonyl (C-1) and hydroxymethylene (C-2) carbons, have been measured at 62.8 MHz. Carbon 169-176 complement C2 Homo sapiens 164-167 6853506-3 1983 The 1/fT1p values of C-1 (1100 +/- 120 s-1) and C-2 (712 +/- 290 s-1) and the previously determined tau c (0.74 ns) yield Mn2+ to carbon distances of 5.7 +/- 0.3 and 6.1 +/- 0.5 A, respectively. Carbon 130-136 heterogeneous nuclear ribonucleoprotein C Homo sapiens 21-24 6853506-3 1983 The 1/fT1p values of C-1 (1100 +/- 120 s-1) and C-2 (712 +/- 290 s-1) and the previously determined tau c (0.74 ns) yield Mn2+ to carbon distances of 5.7 +/- 0.3 and 6.1 +/- 0.5 A, respectively. Carbon 130-136 complement C2 Homo sapiens 48-51 11596491-2 1983 Therefore, an alternative technique for the visualization of myosin molecules was developed: Myosin molecules are sprayed directly onto glow discharged or silicium-monoxide coated carbon filmed grids, omitting glycerol. Carbon 180-186 myosin heavy chain 14 Homo sapiens 93-99 18173261-1 2008 Reduction of the bis(iminopyridine) FeCl(2) complex {2,6-[2,6-(iPr)(2)PhN=C(CH(3))](2)(C(5)H(3)N)}FeCl(2) using NaH has led to the formation of a surprising variety of structures depending on the amount of reductant. Carbon 38-39 carbamoyl-phosphate synthase 1 Homo sapiens 70-73 6845372-5 1983 These data suggest that the methylene carbon plays an important role in cytochrome P-450 induction. Carbon 38-44 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 72-88 2503710-12 1989 The response to the carbon source was reduced dramatically when the same lacZ fusion was present in a hap2 or hap3 mutant. Carbon 20-26 transcription activator HAP2 Saccharomyces cerevisiae S288C 102-106 2503710-12 1989 The response to the carbon source was reduced dramatically when the same lacZ fusion was present in a hap2 or hap3 mutant. Carbon 20-26 Hap3p Saccharomyces cerevisiae S288C 110-114 18181582-6 2008 COMT-specific oligonucleotides were immobilized onto the carbon surface with a simple adsorption method in two different modes: (a) Guanine-containing targets were attached or (b) inosine-substituted probes were attached onto an electrode. Carbon 57-63 catechol-O-methyltransferase Homo sapiens 0-4 2660100-2 1989 The 19 alpha-carbon atoms of the L7/L12 alpha-helices superimpose on the DNA binding helices of CAP and cro with root-mean-square distances between corresponding alpha carbons of 1.45 and 1.55 A, respectively. Carbon 13-19 ribosomal protein L12 Homo sapiens 36-39 2660100-2 1989 The 19 alpha-carbon atoms of the L7/L12 alpha-helices superimpose on the DNA binding helices of CAP and cro with root-mean-square distances between corresponding alpha carbons of 1.45 and 1.55 A, respectively. Carbon 168-175 ribosomal protein L12 Homo sapiens 36-39 6298084-2 1983 We examined the relationship between the ability of I-3-C to alter the activity of hepatic aryl hydrocarbon hydroxylase (AHH), and its ability to inhibit the covalent binding of benzo[a]pyrene (BaP) metabolites to DNA and protein. Carbon 56-57 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 91-119 6298084-2 1983 We examined the relationship between the ability of I-3-C to alter the activity of hepatic aryl hydrocarbon hydroxylase (AHH), and its ability to inhibit the covalent binding of benzo[a]pyrene (BaP) metabolites to DNA and protein. Carbon 56-57 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 121-124 18227254-5 2008 Strains lacking CTN1 or CTN2 were unable to grow on ethanol or acetate as sole carbon source; additionally, citrate was utilized poorly (Deltactn2) or not at all (Deltactn1) and the Deltactn2 mutant failed to grow on fatty acids as well. Carbon 79-85 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 16-20 6862092-6 1983 At early time intervals (0.5-8 hr), [1-14C]glucose 6-phosphate introduced 14C into C-1, C-3 and C-5 of ribose 5-phosphate, at 17 hr 14C was confined to C-1. Carbon 41-42 complement C5 Rattus norvegicus 96-99 2670552-1 1989 The Saccharomyces cerevisiae END1 gene is required for formation or maintenance of the vacuole, for growth on non-fermentable carbon sources, for efficient mating and for growth at 37 degrees C. The END1 gene was cloned by complementation of the end1 mutation. Carbon 126-132 tethering complex subunit PEP5 Saccharomyces cerevisiae S288C 29-33 2670552-1 1989 The Saccharomyces cerevisiae END1 gene is required for formation or maintenance of the vacuole, for growth on non-fermentable carbon sources, for efficient mating and for growth at 37 degrees C. The END1 gene was cloned by complementation of the end1 mutation. Carbon 126-132 tethering complex subunit PEP5 Saccharomyces cerevisiae S288C 199-203 2912723-6 1989 We have also investigated the binding of adenoviral VAI RNA to the purified p68 kinase and have found that the affinity of this binding is lower than that of poly(I).poly(C). Carbon 171-172 eukaryotic translation initiation factor 2 alpha kinase 2 Homo sapiens 76-86 6420775-3 1983 The unambiguous assignment of the proton resonances was established by correlating with the C-13 NMR spectrum of the complex from [N-15]AMP, which showed a doublet for the C-1" carbon signal due to the spin coupling with N-15 (N-9). Carbon 177-183 heterogeneous nuclear ribonucleoprotein C Homo sapiens 92-95 21201461-1 2008 In the title compound, C(20)H(19)N(2) (+) PF(6) (-), the two benzocyclo-butene units are essentially planar and they form dihedral angles of 38.0 (2) and 72.7 (2) , with the central imidazolium ring. Carbon 23-25 sperm associated antigen 17 Homo sapiens 42-47 6815172-1 1982 The exchange of glycine carboxyl carbon with CO2 catalyzed by the combination of chicken liver glycine decarboxylase (P-protein) and aminomethyl carrier protein (H-protein) was markedly inhibited by various divalent cations, although extents of inhibition by individual metal ions varied considerably. Carbon 33-39 OCA2 melanosomal transmembrane protein Gallus gallus 118-127 17932459-4 2008 AtATG6-AS plants produced fewer Monodansylcadaverine (MDC) and LysoTracker (LT) stained-autolysosomes in response to carbon and nitrogen starvation indicating that AtATG6 plays a role in the autophagic pathway in Arabidopsis. Carbon 117-123 AUTOPHAGY 6 Arabidopsis thaliana 0-6 6292686-2 1982 The triarylmethane dye, gentian violet, is shown to undergo a one-electron reduction by the cytochrome P-450 monooxygenase system to produce a carbon-centered free radical as demonstrated by direct electron spin resonance techniques. Carbon 143-149 cytochrome P450 family 20 subfamily A member 1 Homo sapiens 92-122 2925957-6 1989 Postabsorptive use of nitrogen and carbon was altered by somatotropin as reflected by greater secretion in milk. Carbon 35-41 somatotropin Bos taurus 57-69 17932459-4 2008 AtATG6-AS plants produced fewer Monodansylcadaverine (MDC) and LysoTracker (LT) stained-autolysosomes in response to carbon and nitrogen starvation indicating that AtATG6 plays a role in the autophagic pathway in Arabidopsis. Carbon 117-123 AUTOPHAGY 6 Arabidopsis thaliana 164-170 18294131-6 2008 In cytosol the activity of exopolyphosphatase PPN1 was increased and the activity of exopolyphosphatase PPX1 was decreased independently of the carbon source under phosphate surplus conditions. Carbon 144-150 exopolyphosphatase Saccharomyces cerevisiae S288C 104-108 3243762-4 1988 Both 1H-NMR and 13C-NMR showed that the signals of protons and carbons at O-CH3, C-1, and C-2 positions were shifted downfield due to the formation of a double bond between the C-1 and C-2, and that each signal derived from O-CH3, C-1, or C-2 position was divided into two signals due to the formation of cis and trans isomers of the alkenylmethylether. Carbon 63-70 heterogeneous nuclear ribonucleoprotein C Homo sapiens 81-84 3243762-4 1988 Both 1H-NMR and 13C-NMR showed that the signals of protons and carbons at O-CH3, C-1, and C-2 positions were shifted downfield due to the formation of a double bond between the C-1 and C-2, and that each signal derived from O-CH3, C-1, or C-2 position was divided into two signals due to the formation of cis and trans isomers of the alkenylmethylether. Carbon 63-70 complement C2 Homo sapiens 90-93 3243762-4 1988 Both 1H-NMR and 13C-NMR showed that the signals of protons and carbons at O-CH3, C-1, and C-2 positions were shifted downfield due to the formation of a double bond between the C-1 and C-2, and that each signal derived from O-CH3, C-1, or C-2 position was divided into two signals due to the formation of cis and trans isomers of the alkenylmethylether. Carbon 63-70 heterogeneous nuclear ribonucleoprotein C Homo sapiens 177-180 3243762-4 1988 Both 1H-NMR and 13C-NMR showed that the signals of protons and carbons at O-CH3, C-1, and C-2 positions were shifted downfield due to the formation of a double bond between the C-1 and C-2, and that each signal derived from O-CH3, C-1, or C-2 position was divided into two signals due to the formation of cis and trans isomers of the alkenylmethylether. Carbon 63-70 complement C2 Homo sapiens 185-188 3243762-4 1988 Both 1H-NMR and 13C-NMR showed that the signals of protons and carbons at O-CH3, C-1, and C-2 positions were shifted downfield due to the formation of a double bond between the C-1 and C-2, and that each signal derived from O-CH3, C-1, or C-2 position was divided into two signals due to the formation of cis and trans isomers of the alkenylmethylether. Carbon 63-70 heterogeneous nuclear ribonucleoprotein C Homo sapiens 177-180 6456145-8 1981 The most effective inhibitors were the all-trans C17-aldehyde (beta-ionylideneacetaldehyde) or C18-ketone (beta-ionylidenepent-3-ene-2-one) which, compared to retinal, lack two or three carbon atoms from the end of the poylene chain. Carbon 186-192 cytokine like 1 Homo sapiens 49-52 6794031-1 1981 The in vivo flux of carbon through the pentose shunt is investigated as a function of different 6-phosphogluconate dehydrogenase (6Pgd) and glucose-6-phosphate dehydrogenase (G6pd) genotypes by using differential radioactive labeling of the C-1 and C-6 positions of glucose. Carbon 20-26 Phosphogluconate dehydrogenase Drosophila melanogaster 96-128 6794031-1 1981 The in vivo flux of carbon through the pentose shunt is investigated as a function of different 6-phosphogluconate dehydrogenase (6Pgd) and glucose-6-phosphate dehydrogenase (G6pd) genotypes by using differential radioactive labeling of the C-1 and C-6 positions of glucose. Carbon 20-26 Phosphogluconate dehydrogenase Drosophila melanogaster 130-134 6794031-2 1981 Alternative 6Pgd-G6pd genotypes are shown to differ in relative in vivo carbon flux through the pentose shunt. Carbon 72-78 Phosphogluconate dehydrogenase Drosophila melanogaster 12-16 3243762-4 1988 Both 1H-NMR and 13C-NMR showed that the signals of protons and carbons at O-CH3, C-1, and C-2 positions were shifted downfield due to the formation of a double bond between the C-1 and C-2, and that each signal derived from O-CH3, C-1, or C-2 position was divided into two signals due to the formation of cis and trans isomers of the alkenylmethylether. Carbon 63-70 complement C2 Homo sapiens 185-188 18324655-1 2008 A series of technically and economically important element chlorides-such as SiCl4, BCl3, AlCl3, FeCl2, PCl3 and TiCl4-was synthesized through reactions between hydrogen chloride and the corresponding element oxides in the presence of different carbon sources with microwave assistance. Carbon 245-251 PHD finger protein 19 Homo sapiens 104-108 3237207-4 1988 This locus, designated rib-2 in yeast mitochondrial DNA, corresponds to residue C-2611 in the 23 S rRNA of Escherichia coli. Carbon 80-81 bifunctional DRAP deaminase/tRNA pseudouridine synthase RIB2 Saccharomyces cerevisiae S288C 23-28 7440562-9 1980 P-protein alone could also slightly catalyze the exchange of carboxyl carbon of glycine with CO2 and the exchange appeared to obey a ping-pong mechanism. Carbon 70-76 OCA2 melanosomal transmembrane protein Gallus gallus 0-9 17549431-8 2008 This work suggests an important role of GAPN in the regulation of carbon degradation via modifications of the EMP and the branched ED pathway in hyperthermophilic Archaea. Carbon 66-72 SULA_RS08180 Saccharolobus solfataricus 40-44 7372583-3 1980 Some of the carbons of the proline residues of glycoprotein 6 are also identified. Carbon 12-19 glycoprotein VI platelet Homo sapiens 47-61 2847778-5 1988 For this determination, the malate product (containing the carbon of interest at C-2) was quantitatively transformed into a new sample of malate having the carbon of interest at C-4. Carbon 59-65 complement C2 Homo sapiens 81-84 3379303-9 1988 When macrophages were exposed to poly [I:C] in the presence of an anti-mouse IFN-alpha/beta antiserum, the changes in the synthesis of factor B, C3, and beta-glucuronidase were partially inhibited. Carbon 41-42 glucuronidase, beta Mus musculus 153-171 7426684-2 1980 The participation of the C-1 carbon atom in the formation of this ion has been quantitatively determined from the spectra of 13C labelled permethylated glucofuranosides. Carbon 29-35 heterogeneous nuclear ribonucleoprotein C Homo sapiens 25-28 19213327-9 2008 At potentials below 0.6 V NHE, CO, which forms via the non-Faradaic hydrolytic splitting of the C-O bond over stepped or defect sites in the indirect path, can build up and poison the surface. Carbon 31-32 solute carrier family 9 member C1 Homo sapiens 26-29 7353039-2 1980 These data imply that the orientation of the heme group in the major cytochrome b5 conformation in solution differs from that reported for the X-ray crystal structure by a 180 degree rotation about an axis through the meso-carbon atoms alpha and gamma. Carbon 223-229 cytochrome b5 type A Homo sapiens 69-82 17851256-11 2008 CONCLUSIONS: The data indicate that poly I:C internalized by ASM cells differentially regulates M2R and M3R expression and function by interacting with TLR3 rather than with PKR, suggesting that these changes may contribute to airway hyperreactivity. Carbon 0-1 toll like receptor 3 Homo sapiens 152-156 43143-10 1979 Carbon atoms C-2, C-3 and C-4 of the acetoacetate produced were derived from the carbon skeleton of the 4-methyl-2-oxopentanoate, but the acetoacetate carboxy group was derived from the incorporation of CO2. Carbon 0-6 complement C2 Rattus norvegicus 13-21 2897059-9 1988 This elevated level of PAF in fetal lung may serve to facilitate breakdown of glycogen that provides, in part, the carbon and energy source for surfactant biosynthesis. Carbon 115-121 PCNA clamp associated factor Homo sapiens 23-26 3337720-3 1988 A non-cyclic pathway is suggested (reaction 2) for the direct biosynthesis of sucrose from the 3-PGA obtained from C-3, C-4 and C-5 of the six-carbon carboxylation adduct. Carbon 143-149 complement C4A (Rodgers blood group) Homo sapiens 120-123 3337720-3 1988 A non-cyclic pathway is suggested (reaction 2) for the direct biosynthesis of sucrose from the 3-PGA obtained from C-3, C-4 and C-5 of the six-carbon carboxylation adduct. Carbon 143-149 complement C5 Homo sapiens 128-131 19209629-5 2008 Carbon density of the regional forest increased by 14.31%, from 19.08 to 21.81 ton/hm2. Carbon 0-6 cholinergic receptor muscarinic 2 Homo sapiens 83-86 3126806-1 1987 Thymidylate synthase (TS), 5-fluorodeoxyuridylate (FdUMP), and 5,10-methylenetetrahydrofolate (CH2-H4folate) form a covalent complex in which a Cys thiol of TS is attached to the 6-position of FdUMP and the one-carbon unit of the cofactor is attached to the 5-position. Carbon 211-217 thymidylate synthetase Homo sapiens 0-20 227369-10 1979 During carbon-limited growth the cytochrome c becomes bound to the membrane in such a way that it can mediate between cytochromes b and a/a(3), hence becoming involved in proton translocation and ATP synthesis during NADH and succinate oxidation. Carbon 7-13 MEXAM1_RS12150 Methylobacterium extorquens AM1 33-45 227369-11 1979 An alternative possibility is that in wild-type bacteria the cytochrome c is always involved in electron transport, but that its involvement in measurable proton translocation only occurs in carbon-limited conditions. Carbon 191-197 MEXAM1_RS12150 Methylobacterium extorquens AM1 61-73 18349550-0 2008 Escherichia coli arcA mutants: metabolic profile characterization of microaerobic cultures using glycerol as a carbon source. Carbon 111-117 arginine deiminase Escherichia coli 17-21 571739-2 1979 Phosphoenolpyruvate carboxylase (orthophosphate:oxaloacetate carboxylase (phosphorylating), EC 4.1.1.31) from plant cells of soybean nodules was studied to assess its role in providing carbon skeletons for aspartate and asparagine synthesis. Carbon 185-191 phosphoenolpyruvate carboxylase, housekeeping isozyme Glycine max 0-31 3297651-2 1987 Insulin action (measured as the effect on incorporation of acetate-carbon into long-chain fatty acids) was unaffected by bGH in short term incubations regardless of whether hydrocortisone (HC) was present. Carbon 67-73 insulin Bos taurus 0-7 18031036-2 2007 The crystal structure reveals a bent Fe-N-O geometry and an eta2-(C,S) bonding mode between iron and the C-S bond. Carbon 66-67 DNA polymerase iota Homo sapiens 60-64 3040523-2 1987 Growth of yeast cells in a medium containing only nonfermentable carbon sources leads to a marked increase or derepression of ADH2 expression. Carbon 65-71 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 126-130 3117106-3 1987 In both cases, the C-C bond formation was found to take place at the si face of the double bond with elimination of one of the hydrogens of C-2 in a syn fashion. Carbon 19-20 complement C2 Homo sapiens 140-143 762221-6 1979 A significant difference (P less than 0.01) has been found in the group of hypophyseal adenomas in which the amounts of practically all saturated FAME"S with an odd carbon number are elevated. Carbon 165-171 benign adult familial myoclonic epilepsy 1 Homo sapiens 146-150 208152-2 1978 This reaction completes a plausible prebiotic synthesis of uracil and its derivatives starting from HCN as the only carbon source. Carbon 116-122 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 100-103 3117106-3 1987 In both cases, the C-C bond formation was found to take place at the si face of the double bond with elimination of one of the hydrogens of C-2 in a syn fashion. Carbon 21-22 complement C2 Homo sapiens 140-143 21200813-1 2007 The cation of the title salt, C(34)H(45)N(2) (+) PF(6) (-), is a protonated form of an unsymmetrical overcrowded beta-imino-amine. Carbon 30-31 sperm associated antigen 17 Homo sapiens 49-54 2821940-6 1987 Compounds containing C = O in the spacing moiety were active inhibitors of cholinesterase with some derivatives being nearly as active as physostigmine. Carbon 0-1 butyrylcholinesterase Homo sapiens 75-89 580344-4 1978 The magnitude of the insulin effect, subsequently assayed on the accumulation of glucose carbon and the distribution of 3-0-methylglucose, was found to increase with the time of prior exposure to insulin, approaching a maximum after about 120 min. Carbon 89-95 insulin Bos taurus 21-28 580344-4 1978 The magnitude of the insulin effect, subsequently assayed on the accumulation of glucose carbon and the distribution of 3-0-methylglucose, was found to increase with the time of prior exposure to insulin, approaching a maximum after about 120 min. Carbon 89-95 insulin Bos taurus 196-203 17933539-1 2007 A composite carbon fibre polyester scaffold class ligament (ABC -- Active Biosynthetic Composite Ligament, Surgicraft Ltd., Redditch) has been used for primary reconstruction of the torn anterior cruciate ligament at Mayday University Hospital since 1985. Carbon 12-18 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 60-63 596868-2 1977 Thermophilic strains CC-6, BI-1, and LEH-1, grown with acetate or n-heptadecane as the carbon source, had a higher survival rate when incubated 5 degrees C above their maximum growth temperature than cells of the same organism after growth on glucose or glycerol. Carbon 87-93 NADH:ubiquinone oxidoreductase subunit A9 Homo sapiens 21-25 3037314-3 1987 Strains of S. cerevisiae with disrupted BCY1 genes do not display a cyclic AMP-dependent protein kinase in vitro, fail to grow on many carbon sources, and are exquisitely sensitive to heat shock and starvation. Carbon 135-141 cAMP-dependent protein kinase regulatory subunit BCY1 Saccharomyces cerevisiae S288C 40-44 17927693-6 2007 Expression of PHR1 in the phr1 mutant rescues the responsiveness to P-starvation and leads to WT levels of sugars and starch during Pi starvation conditions, confirming the involvement of PHR1 in adjusting carbon metabolism. Carbon 206-212 photolyase 1 Arabidopsis thaliana 14-18 299858-7 1977 The most prominent difference between W/Wv and Sl/Sla mice and their normal counterparts was observed in the inductionof CFU-C from splenic precursors un-er the influence of CSA. Carbon 121-126 src-like adaptor Mus musculus 50-53 17927693-6 2007 Expression of PHR1 in the phr1 mutant rescues the responsiveness to P-starvation and leads to WT levels of sugars and starch during Pi starvation conditions, confirming the involvement of PHR1 in adjusting carbon metabolism. Carbon 206-212 photolyase 1 Arabidopsis thaliana 26-30 17939658-5 2007 The homolytic cleavage of one C-Br bond in the parent CBr4 molecule yields the CBr3 and Br radicals, which escape from the solvent cage and combine nongeminately to form C2Br6 and Br2, respectively. Carbon 30-31 carbonyl reductase 3 Homo sapiens 79-83 786369-1 1976 The adsorption of thymidylate synthetase from Escherichia coli B to aminoalkyl-Sepharose with the increasing length of carbon chain (2--6 carbon atoms) was investigated. Carbon 119-125 thymidylate synthetase Bos taurus 18-40 786369-1 1976 The adsorption of thymidylate synthetase from Escherichia coli B to aminoalkyl-Sepharose with the increasing length of carbon chain (2--6 carbon atoms) was investigated. Carbon 138-144 thymidylate synthetase Bos taurus 18-40 3036209-1 1987 The carbon kinetic isotope effect on the enzymatic dehydration of HCO3- ion is k12/k13 = 1.011 and is independent, within experimental error, of the addition of sucrose, substitution of D2O for H2O, and substitution of enzyme-bound Zn2+ by Co2+. Carbon 4-10 complement C2 Homo sapiens 240-243 2434233-1 1987 Somatomedin C (Sm-C; insulin-like growth factor I; IGF-I) is a polypeptide (Mr 7649), often dependent on growth hormone (GH), with trophic effects on several different tissues. Carbon 12-13 insulin-like growth factor 1 Rattus norvegicus 21-49 2434233-1 1987 Somatomedin C (Sm-C; insulin-like growth factor I; IGF-I) is a polypeptide (Mr 7649), often dependent on growth hormone (GH), with trophic effects on several different tissues. Carbon 12-13 insulin-like growth factor 1 Rattus norvegicus 51-56 17929966-3 2007 A polymer conjugated to the 4-hydroxytamoxifen analogue with a six-carbon linker showed high affinity for both estrogen receptor alpha and estrogen receptor beta and potent antagonism of the estrogen receptor in cell-based transcriptional reporter assays. Carbon 67-73 estrogen receptor 2 Homo sapiens 139-161 3542971-2 1987 Aerobically, L-lactaldehyde serves as a carbon and energy source by the action of an aldehyde dehydrogenase of broad specificity; the product, L-lactate, is then converted to pyruvate. Carbon 40-46 Aldehyde dehydrogenase Escherichia coli 85-107 3542971-12 1987 Complete aerobic utilization of carbons 4 through 6 of L-fucose depends not only on an adequate activity of aldehyde dehydrogenase to trap L-lactaldehyde as its anionic acid but also on the lack of L-1,2-propanediol oxidoreductase activity, which converts L-lactaldehyde to a readily excreted alcohol. Carbon 32-39 Aldehyde dehydrogenase Escherichia coli 108-130 177419-2 1976 Phosphoenolpyruvate carboxylase from Pseudomonas MA, grown on methylamine as a sole carbon source, has been studied with respect to some of its regulatory properties. Carbon 84-90 phosphoenolpyruvate carboxykinase 1 Homo sapiens 0-31 1106342-3 1975 Subsequent analysis of the mycelium produced under Mn2+ deficient growth revealed that alpha-1,3 glucan, the man carbon and energy source for fructification, was virtually absent from the cell wall. Carbon 113-119 adrenoceptor alpha 1D Homo sapiens 87-96 17712601-4 2007 The smaller AtCOX19-1 isoform, but not the larger one, is able to restore growth on non-fermentable carbon sources when expressed in a yeast cox19 null mutant. Carbon 100-106 cytochrome c oxidase 19-1 Arabidopsis thaliana 12-21 1138993-3 1975 Enzymic oxidation of UDP-glucose-6-3-H with calf liver UDP-glucose dehydrogenase was found to proceed with direct transfer of the hydrogen from C-6 of UDP-glucose onto NAD. Carbon 144-145 UDP-glucose 6-dehydrogenase Bos taurus 55-80 3806609-4 1987 Inhibition of 5-lipoxygenase by 15-hydroxyeicosa-11,13-dienoic acid (15-HEDE) analogues was optimal in compounds that generally contained a free carboxyl group, a carboxylate side chain of nine carbons, an omega side chain of five or six carbons, a cis,trans- or trans,cis-11,13-diene or 11,13-diyne system, and a 15-hydroxyl group. Carbon 194-201 arachidonate 5-lipoxygenase Rattus norvegicus 14-28 3806609-4 1987 Inhibition of 5-lipoxygenase by 15-hydroxyeicosa-11,13-dienoic acid (15-HEDE) analogues was optimal in compounds that generally contained a free carboxyl group, a carboxylate side chain of nine carbons, an omega side chain of five or six carbons, a cis,trans- or trans,cis-11,13-diene or 11,13-diyne system, and a 15-hydroxyl group. Carbon 238-245 arachidonate 5-lipoxygenase Rattus norvegicus 14-28 17720756-0 2007 Regulation of one-carbon metabolism in Arabidopsis: the N-terminal regulatory domain of cystathionine gamma-synthase is cleaved in response to folate starvation. Carbon 18-24 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein Arabidopsis thaliana 88-116 2453298-4 1987 The mutation, mna1-1, is especially interesting since it causes a loss of both mitochondrial DNA and RNA when the mutant is grown on a fermentable carbon source at the restrictive temperature. Carbon 147-153 dynamin-related GTPase MGM1 Saccharomyces cerevisiae S288C 14-20 19396987-8 1974 (4) It is postulated that with pyruvate as substrate, recycling of carbon via pyruvate carboxylase, phosphoenolpyruvate carboxylase and pyruvate kinase (ATP: pyruvate phosphotransferase, EC 2.7.1.40) is an important, energy-requiring, mechanism for the transfer of the proportion of NADH not directly associated with gluconeogenesis. Carbon 67-73 phosphoenolpyruvate carboxykinase 1 Homo sapiens 100-131 4634828-4 1972 The carbon skeletons of formate and succinate were shown to arise from the C-2 and the C-3-C-6 atoms of the heterocyclic ring respectively by using N-methyl[2,3-(14)C(2)]isonicotinate. Carbon 4-10 complement C2 Homo sapiens 75-78 17524547-3 2007 In both cases, the chimeric carrier, Anc2-Cyc1(His6)p, was able to restore growth on a non-fermentable carbon source of a yeast strain devoid of functional ADP/ATP carrier, demonstrating its transport activity. Carbon 103-109 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 37-41 16058487-1 1970 Pollen and carbon dating suggest that the Post-Glacial spread of the spruce (Picea) in Switzerland has been influenced by human activity. Carbon 11-17 solute carrier family 35 member G1 Homo sapiens 42-46 3550104-1 1986 The effect of temperature on the length of the tail of the myosin molecule has been studied by negative staining of molecules immobilized on carbon substrates at different temperatures. Carbon 141-147 myosin heavy chain 14 Homo sapiens 59-65 3529088-3 1986 Thus, the c-ros gene joins the c-myb oncogene, which is distal to the c-ros gene on the long arm of human chromosome 6, as a candidate for involvement in chromosome 6q deletions and rearrangements seen in various malignancies. Carbon 10-11 MYB proto-oncogene, transcription factor Homo sapiens 31-36 17524547-3 2007 In both cases, the chimeric carrier, Anc2-Cyc1(His6)p, was able to restore growth on a non-fermentable carbon source of a yeast strain devoid of functional ADP/ATP carrier, demonstrating its transport activity. Carbon 103-109 1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase HIS6 Saccharomyces cerevisiae S288C 47-51 3013435-2 1986 Use of the spin traps N-tert-butyl-alpha-phenylnitrone (PBN) and 2-methyl-2-nitrosopropane provides evidence for photolytic cleavage of carbon-halogen bonds yielding radicals such as .CCl3 (from CCl4 and CBrCl3) and .CHClCF3 (from halothane) which are readily trapped; this method of generating biologically important radicals may be of use in studying model reactions of these species. Carbon 136-142 C-C motif chemokine ligand 3 Homo sapiens 184-188 3013435-2 1986 Use of the spin traps N-tert-butyl-alpha-phenylnitrone (PBN) and 2-methyl-2-nitrosopropane provides evidence for photolytic cleavage of carbon-halogen bonds yielding radicals such as .CCl3 (from CCl4 and CBrCl3) and .CHClCF3 (from halothane) which are readily trapped; this method of generating biologically important radicals may be of use in studying model reactions of these species. Carbon 136-142 C-C motif chemokine ligand 4 Homo sapiens 195-199 16056915-0 1970 Isotopic evidence for diminishing supply of available carbon during diatom bloom in the Black Sea. Carbon 54-60 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 94-97 17994867-2 2007 This study represents the first attempt, to our knowledge, to demonstrate the capability of PAFC with tunable near-infrared (NIR) pulse lasers for real-time monitoring of gold nanorods, Staphylococcus aureus and Escherichia coli labeled with carbon nanotubes (CNTs), and contrast dye Lymphazurin in the microvessels of mouse and rat ears and mesenteries. Carbon 242-248 PAFC Homo sapiens 92-96 17792852-1 1967 Radioactive carbon determinations of the age of peat indicate that at Bermuda, southern Florida, North Carolina, and Louisiana the relative sea level has risen at approximately the same rate, 2.5 x 10(-3) foot per year (0.76 x 10(-3) meter per year), during the past 4000 years. Carbon 12-18 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 140-143 13950637-0 1963 [C-14 labelling and peptide charts of the SH regions of actomyosin, myosin, actin and H-meromyosin]. Carbon 1-2 myosin heavy chain 14 Homo sapiens 60-66 16453671-2 1986 The presence of the inducible GAL1-10 upstream activation site (UAS) allows us to regulate differentially by carbon sources the transcription of the zein gene both under the plant promoter and under the yeast CYC-1 promoter. Carbon 109-115 cytochrome c isoform 1 Saccharomyces cerevisiae S288C 209-214 17690534-10 2007 The genes showing significantly lower expressions after X-ray irradiation rather than after carbon-ion beam irradiation were RAD50, BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. Carbon 92-98 RAD50 double strand break repair protein Homo sapiens 125-130 17690534-10 2007 The genes showing significantly lower expressions after X-ray irradiation rather than after carbon-ion beam irradiation were RAD50, BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. Carbon 92-98 cyclin B2 Homo sapiens 174-179 3824405-7 1986 Addition of side groups resulted in reduced effectiveness only when an acetyl group was added to the carbon 3 position of T-2 (acetyl T-2) and deoxynivalenol (3-acetyl deoxynivalenol) or on substitution of an epoxide across the 9,10 carbons of diacetoxyscirpenol (beta-epoxide DAS). Carbon 233-240 brachyury 2 Rattus norvegicus 134-137 34030414-8 2021 When applied in removal of CIP at the low concentration of 2.0 microg mL-1, a high removal efficiency of 96.60% was still obtained, which was superior to commercial activated carbon (28.78%). Carbon 175-181 L1 cell adhesion molecule Mus musculus 70-74 3824405-3 1986 The most potent mycotoxins (T-2, verrucarin A and roridin A) have acetyl side groups on, or a hydrocarbon chain between, carbons 4 and 15 of the basic ring structure. Carbon 121-128 brachyury 2 Rattus norvegicus 28-31 17482557-1 2007 Folate-activated one-carbon units are derived from serine through the activity of the pyridoxal-phosphate (PLP)-dependent isozymes of serine hydroxymethyltransferase (SHMT). Carbon 21-27 pyridoxal phosphatase Homo sapiens 107-110 3824405-4 1986 Loss of side groups from either of these positions or an isovaleryl group at carbon 8 resulted in reduced protein synthesis inhibition (T-2 to HT-2, neosolaniol or diacetoxyscirpenol). Carbon 77-83 brachyury 2 Rattus norvegicus 136-139 3824405-7 1986 Addition of side groups resulted in reduced effectiveness only when an acetyl group was added to the carbon 3 position of T-2 (acetyl T-2) and deoxynivalenol (3-acetyl deoxynivalenol) or on substitution of an epoxide across the 9,10 carbons of diacetoxyscirpenol (beta-epoxide DAS). Carbon 101-107 brachyury 2 Rattus norvegicus 122-125 3824405-7 1986 Addition of side groups resulted in reduced effectiveness only when an acetyl group was added to the carbon 3 position of T-2 (acetyl T-2) and deoxynivalenol (3-acetyl deoxynivalenol) or on substitution of an epoxide across the 9,10 carbons of diacetoxyscirpenol (beta-epoxide DAS). Carbon 101-107 brachyury 2 Rattus norvegicus 134-137 3824405-7 1986 Addition of side groups resulted in reduced effectiveness only when an acetyl group was added to the carbon 3 position of T-2 (acetyl T-2) and deoxynivalenol (3-acetyl deoxynivalenol) or on substitution of an epoxide across the 9,10 carbons of diacetoxyscirpenol (beta-epoxide DAS). Carbon 233-240 brachyury 2 Rattus norvegicus 122-125 4055772-11 1985 We have concluded that mevalonate, fluoromevalonate, homomevalonate, and compactin (mevinolin) modulated HMG-CoA reductase activity because they altered isoprenoid carbon flow to a post-isopentenyl 1-pyrophosphate regulatory, signal molecule. Carbon 164-170 Pyrroline 5-carboyxlate reductase Drosophila melanogaster 113-122 33839508-2 2021 In this study, adding granular activated carbon (GAC) and increasing the temperature decreased the viscosity by 4.56-10.19% and 27.13-28.85%, respectively, and improved AD efficiency. Carbon 41-47 glutaminase Homo sapiens 49-52 31060401-0 2021 Induction of caspase-2 gene expression in carboxyl-functionalized carbon nanotube-treated human T-cell leukemia (Jurkat) cell line. Carbon 66-72 caspase 2 Homo sapiens 13-22 17650590-8 2007 Higher activities of phosphoglucomutase and fructose-1,6-phosphatase in mungbean cytosolic fraction could lead to increased flow of carbon towards pentose phosphate pathway. Carbon 132-138 uncharacterized protein LOC106771950 Vigna radiata 21-39 33744543-5 2021 Partial removal of CoOx from carbon framework promotes the exposure of highly active sites (Co2+) on the Co3O4. Carbon 29-35 complement C2 Homo sapiens 92-95 4044833-6 1985 The percent 13C enrichment of the glucosyl units in glycogen was: 15.1 +/- 0.8%(C-1), 1.5 +/- 0.1%(C-2), 1.2 +/- 0.1%(C-3), 1.1 +/- 0.1%(C-4), 1.6 +/- 0.1%(C-5), and 2.2 +/- 0.1%(C-6) for the high-dose study (n = 4, at 3 h); 16.5 +/- 0.5%(C-1), 2.0 +/- 0.1%(C-2), 1.3 +/- 0.1%(C-3), 1.1 +/- 0.1%(C-4), 2.2 +/- 0.1%(C-5), and 2.4 +/- 0.1%(C-6) in the low-dose study (n = 4, at 2 h). Carbon 14-15 complement C2 Rattus norvegicus 99-102 3158880-3 1985 Drug activation and the consequent hydrogen abstraction reaction, presumably generating a carbon-centered radical at C-5", do not require molecular oxygen but have a dose-dependent relation with thiol. Carbon 90-96 complement C5 Homo sapiens 117-120 17445548-1 2007 The 10-formyl moiety of 10-formyltetrahydrofolate is the source of carbons at the positions 8 (C(8)) and 2 (C(2)) of the purine ring, originating from formate and a few amino acids. Carbon 67-74 homeobox C8 Homo sapiens 95-99 3881424-0 1985 Regulation of expression of the ADE3 gene for yeast C1-tetrahydrofolate synthase, a trifunctional enzyme involved in one-carbon metabolism. Carbon 121-127 trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 Saccharomyces cerevisiae S288C 32-36 17205343-6 2007 Hence, this element can not only be used to isolate essential DNA-binding protein(s) that control the expression of the carbon metabolic enzyme AtPFPalpha2, but has also the potential to be utilized in the production of useful compounds in a specific organ such as the leaf trichomes. Carbon 120-126 DNA binding protein Arabidopsis thaliana 62-81 3871336-3 1985 The pH dependence of the chemical shift of the C-2 carbon in the histidine ring of carnosine was used for estimation of the intracellular pH in the intact muscle. Carbon 51-57 complement C2 Homo sapiens 47-50 2934294-4 1985 When the carbon source in the culture medium is substituted with ethanol, the transcription from the derepressed ADH2 promoter interferes with the CEN3 function, rendering the YCRp plasmids unstable. Carbon 9-15 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 113-117 33524653-3 2021 Well-characterized Anti-AbsCA19-9/CS-MWCNT-Fe3O4 immune-electrode fabricated on glassy carbon electrode (GCE) successfully detect CA 19-9 and exhibited a high sensitivity as (2.55 microA pg-1 cm-1), a detection limit of 0.163 pg mL-1, detection range from 1.0 pg mL-1 to 100 ng mL-1. Carbon 87-93 L1 cell adhesion molecule Mus musculus 229-233 33524653-3 2021 Well-characterized Anti-AbsCA19-9/CS-MWCNT-Fe3O4 immune-electrode fabricated on glassy carbon electrode (GCE) successfully detect CA 19-9 and exhibited a high sensitivity as (2.55 microA pg-1 cm-1), a detection limit of 0.163 pg mL-1, detection range from 1.0 pg mL-1 to 100 ng mL-1. Carbon 87-93 L1 cell adhesion molecule Mus musculus 263-267 33524653-3 2021 Well-characterized Anti-AbsCA19-9/CS-MWCNT-Fe3O4 immune-electrode fabricated on glassy carbon electrode (GCE) successfully detect CA 19-9 and exhibited a high sensitivity as (2.55 microA pg-1 cm-1), a detection limit of 0.163 pg mL-1, detection range from 1.0 pg mL-1 to 100 ng mL-1. Carbon 87-93 L1 cell adhesion molecule Mus musculus 263-267 33450645-1 2021 An electrochemical deposition method was used to fabricate a gold nanoflower (AuNF) and carbon nanoparticle (CNP) modified carbon paper (CP) sensor (AuNFs-CNPs/CP) for the low-cost detection of 5-methyltetrahydrofolate (5-mTHF) in egg yolk. Carbon 123-129 ceruloplasmin Homo sapiens 160-162 33999053-3 2021 The oxidation peak currents of 1-NAP and 2-NAP on a ZnO/ZnCo2O4 modified carbon paste electrode (ZnO/ZnCo2O4/CPE) depended linearly on their concentrations in the range of 0.4-50 muM and 0.06-40 muM with detection limits of 0.13 and 0.02 muM, respectively. Carbon 73-79 carboxypeptidase E Homo sapiens 109-112 17450924-1 2007 Interaction of the metal-centered free radicals [CpMo(CO)3]* generated photochemically from the corresponding dimer [CpMo(CO)3]2 with fullerenes C60, C70, or single-walled carbon nanotubes in toluene results in the radical-adducts investigated by using TGA, ESR, Raman and X-ray Photo-electron spectroscopy. Carbon 172-178 T-box transcription factor 1 Homo sapiens 253-256 34056000-10 2021 In the radical gastrectomy for distal gastric cancer, carbon nanoparticle laparoscopy was not only helpful for the localization of small tumors but also for the thorough dissection of lymph nodes after the surgery, and the postoperative adverse reactions of carbon nanoparticle laparoscopy were also less, which was of great significance for the improvement of intestinal flora and the reduction of serum levels of EGFR, IL-32, and gastrin 17 in gastric cancer patients. Carbon 54-60 interleukin 32 Homo sapiens 421-426 6092916-0 1984 Disruption of regulatory gene GAL80 in Saccharomyces cerevisiae: effects on carbon-controlled regulation of the galactose/melibiose pathway genes. Carbon 76-82 transcription regulator GAL80 Saccharomyces cerevisiae S288C 30-35 17445553-9 2007 Sparse sample algorithms used to estimate 12-hour AUC including C(0), C(1), C(2), C(3), C(4), and/or C(6) showed a good correlation with the calculated AUC(0-6) (r(2) = .81-.96). Carbon 52-53 complement C6 Homo sapiens 101-105 6092916-2 1984 We have isolated the GAL80 gene and have studied the effect of a null mutation on the carbon-controlled regulation of the MEL1 and GAL cluster genes. Carbon 86-92 transcription regulator GAL80 Saccharomyces cerevisiae S288C 21-26 33980877-5 2021 We found that c-9, t-11-CLA diet-fed AD model mice significantly exhibited (1) a decrease in amyloid-beta protein (Abeta) levels in the hippocampus, (2) an increase in the number of microglia, and (3) an increase in the number of astrocytes expressing the anti-inflammatory cytokines, interleukin-10 and 19 (IL-10, IL-19), with no change in the total number of astrocytes. Carbon 14-15 amyloid beta (A4) precursor protein Mus musculus 115-120 33980877-7 2021 Thus, dietary c-9, t-11-CLA entered the brain and appeared to exhibit beneficial effects on AD, including a decrease in Abeta levels and suppression of inflammation. Carbon 14-15 amyloid beta (A4) precursor protein Mus musculus 120-125 17288422-0 2007 Transition of ionic liquid [bmim][PF6] from liquid to high-melting-point crystal when confined in multiwalled carbon nanotubes. Carbon 110-116 sperm associated antigen 17 Homo sapiens 34-37 33749985-4 2021 The use of fully benzenoid HBC as a bridging moiety leads to significant singlet biradical characters (y0) of 0.72 and 0.96 for mPHBC 8 and pPHBC 16, respectively, due to the strong rearomatization tendency of the HBC p-system; these values are among the highest for planar carbon-centered biradical molecules. Carbon 274-280 keratin 88, pseudogene Homo sapiens 27-30 33749985-4 2021 The use of fully benzenoid HBC as a bridging moiety leads to significant singlet biradical characters (y0) of 0.72 and 0.96 for mPHBC 8 and pPHBC 16, respectively, due to the strong rearomatization tendency of the HBC p-system; these values are among the highest for planar carbon-centered biradical molecules. Carbon 274-280 keratin 88, pseudogene Homo sapiens 130-133 6319214-3 1984 Simultaneous primed continuous infusion of [2-3H] or [3-3H]glucose established that under these conditions absolute carbon flow through hepatic glucose-6-phosphatase was greatly suppressed. Carbon 116-122 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 144-165 17021802-0 2007 Expression of a modified ADP-glucose pyrophosphorylase large subunit in wheat seeds stimulates photosynthesis and carbon metabolism. Carbon 114-120 glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic Triticum aestivum 25-54 6321953-3 1984 This mating type effect on ADH2 expression was greatest in the presence of a normally derepressing carbon source, glycerol, and much less apparent in the presence of a repressing carbon source, glucose. Carbon 99-105 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 27-31 6321953-3 1984 This mating type effect on ADH2 expression was greatest in the presence of a normally derepressing carbon source, glycerol, and much less apparent in the presence of a repressing carbon source, glucose. Carbon 179-185 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 27-31 6321953-5 1984 The mating type effect and aberrant carbon source response in mating-incompetent cells was specific for Ty-associated mutations in the 5" flanking region of the ADH2 gene in that a non-Ty mutation in the same region did not show these effects. Carbon 36-42 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 161-165 33676366-1 2021 BACKGROUND: The carbon isotope ratios (CIRs) of individual amino acids (AAs) may provide more sensitive and specific biomarkers of sugar-sweetened beverages (SSBs) than total tissue CIR. Carbon 16-22 corepressor interacting with RBPJ, CIR1 Homo sapiens 39-42 33963398-0 2021 Thioredoxin m overexpression in chloroplasts alters carbon and nitrogen partitioning in tobacco plants. Carbon 52-58 thioredoxin H-type 1 Nicotiana tabacum 0-11 17593721-3 2007 ENC1 showed higher BET surface area, higher nitrogen-accessible micropore volume, and lower mass of extractable organic chemicals, including quantifiable polycyclic aromatic hydrocarbons (PAHs),while the two chars showed identical surface oxygen/ carbon (O/C) ratio. Carbon 179-185 ectodermal-neural cortex 1 Homo sapiens 0-4 33963398-2 2021 In the present work, the influence of thioredoxin (Trx) m on C and N partitioning was studied using tobacco plants overexpressing Trx m from the chloroplast genome. Carbon 61-62 thioredoxin H-type 1 Nicotiana tabacum 38-49 33963398-2 2021 In the present work, the influence of thioredoxin (Trx) m on C and N partitioning was studied using tobacco plants overexpressing Trx m from the chloroplast genome. Carbon 61-62 thioredoxin H-type 1 Nicotiana tabacum 51-54 33947836-6 2021 KEGG function analysis of these genes revealed that they were mainly enriched in the HIF-1 signaling pathway, NOD-like receptor signaling pathway, central carbon metabolism in cancer, and PPAR signaling pathway. Carbon 155-161 peroxisome proliferator activated receptor alpha Homo sapiens 188-192 6348555-3 1983 Conversely, growth on a non-fermentable carbon source such as ethanol or glycerol results in derepression of ADR2, and repression of ADC1. Carbon 40-46 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 109-113 6348555-6 1983 The second class of mutants do revert to a glucose-repressed phenotype at a detectable frequency, and when grown on non-fermentable carbon sources derepress ADR2 to levels up to five times those found in wild-type cells. Carbon 132-138 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 157-161 6874684-1 1983 The fatty acid specificity of the bile salt-activated lipase purified from human milk was studied using C12 to C54 (total acyl carbon) saturated and the C54 unsaturated triacylglycerols. Carbon 127-133 carboxyl ester lipase Homo sapiens 34-60 17593721-3 2007 ENC1 showed higher BET surface area, higher nitrogen-accessible micropore volume, and lower mass of extractable organic chemicals, including quantifiable polycyclic aromatic hydrocarbons (PAHs),while the two chars showed identical surface oxygen/ carbon (O/C) ratio. Carbon 2-3 delta/notch like EGF repeat containing Homo sapiens 19-22 34044194-1 2021 High quantum yield 3-aminophenylboronic acid-functionalized nitrogen-doped carbon dots (GAAP-CDs) were fabricated using a simple hydrothermal route and used as a sensing probe for toxic hypochlorite (ClO-). Carbon 75-81 transmembrane BAX inhibitor motif containing 4 Homo sapiens 88-92 17157197-1 2007 A yeast mutant lacking the two major cytosolic sources of NADPH, glucose-6-phosphate dehydrogenase (Zwf1p) and NADP+-specific isocitrate dehydrogenase (Idp2p), has been demonstrated to lose viability when shifted to medium with acetate or oleate as the carbon source. Carbon 253-259 isocitrate dehydrogenase (NADP(+)) IDP2 Saccharomyces cerevisiae S288C 152-157 33565386-8 2021 In silico docking of AV constituents reveal higher negative binding affinity for C and O- glycosides for HIF-1a, IL-6, Janus kinase 1/3, TNF-alpha and TGF- beta -key players of hypoxia-inflammation. Carbon 81-82 hypoxia inducible factor 1, alpha subunit Mus musculus 105-111 6406501-8 1983 Kinetic evidence also was obtained which indicated that the base which accepts the proton from the C-2 carbon atom of the substrate must be aprotic. Carbon 103-109 complement C2 Homo sapiens 99-102 16956696-6 2007 Furthermore, [(3)H]taurine and [(14)C]creatine uptake were concomitantly increased following exposure to ammonia, suggesting that up-regulation of both TAUT and CRT under hyperammonemic conditions results in an increased function of these two transporters in TM-BBB cells. Carbon 36-37 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 Mus musculus 152-156 6845372-0 1983 Induction of cytochrome P-450 by methylenedioxyphenyl compounds: importance of the methylene carbon. Carbon 93-99 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 13-29 6850949-4 1983 In contrast, in the vesicles containing etherdeoxylysoPC, all three glycerol carbon signals make their appearance, with the T*2 of C-2 approaching the T*2 in the monomolecularly dissolved lysolipid. Carbon 77-83 complement C2 Homo sapiens 131-134 34025139-8 2021 However, the treatment of RGE or SF in HaCaT cells in the presence of poly I:C, a toll-like receptor (TLR) 3 ligand, before UV exposure elicited the inhibition of the IL-1beta secretion. Carbon 41-42 interleukin 1 alpha Homo sapiens 167-175 33907205-6 2021 The present study shows that the use of unreduced GO inhibits the solid-state reaction between ThO2 and C; on the other hand, the high reactivity of the ThC2 so produced is expected to be beneficial for the 225Ac production with the ISOL method, affording a high release efficiency. Carbon 104-105 ankyrin repeat domain containing 26 Homo sapiens 153-157 17085512-5 2007 The effects of nitrogen supply, light duration, light intensity, and carbon on the expression of the AtAmt1.1 gene in the roots and aerial tissues are reported. Carbon 69-75 ammonium transporter 1;1 Arabidopsis thaliana 101-109 33891343-0 2021 One-Step Template/Solvent-Free Pyrolysis for in-situ Immobilization of CoP Nanoparticles onto N and P co-Doped Carbon Porous Nanosheets towards High-efficiency Electrocatalytic Hydrogen Evolution. Carbon 112-118 caspase recruitment domain family member 16 Homo sapiens 72-75 16861002-4 2007 After passive immobilization onto a carbon surface both forms of the CD14 fusion proteins bound LPS-biotin in a dose-dependent manner in an electrochemiluminescent assay. Carbon 36-42 CD14 molecule Homo sapiens 69-73 33894159-7 2021 Thus, NAAG, lactate, and GABA can play important roles as storage molecules for glutamate, glucose, and succinate carbon in oncogenic MYC-transformed P493 lymphoma B cells (MYC-ON cells) but not in non-oncogenic MYC-OFF cells. Carbon 114-120 MYC proto-oncogene, bHLH transcription factor Homo sapiens 134-137 17464365-3 2007 The alpha-substituents on the pyrrole ring (H, Br, CHO) and pyrroline ring (H, CH(3), CH(OR)(2), OMe, SMe) provide different reactivity combinations (Nu(-), E(+)) and 0, 1, or 2 carbon atoms (which can give rise to the bridging meso-carbons in hydroporphyrins). Carbon 178-184 small nuclear ribonucleoprotein polypeptide E Homo sapiens 102-105 33992966-0 2021 The electrochemical detection of prostate specific antigen on glassy carbon electrode modified with combinations of graphene quantum dots, cobalt phthalocyanine and an aptamer. Carbon 69-75 kallikrein related peptidase 3 Homo sapiens 33-58 17464365-3 2007 The alpha-substituents on the pyrrole ring (H, Br, CHO) and pyrroline ring (H, CH(3), CH(OR)(2), OMe, SMe) provide different reactivity combinations (Nu(-), E(+)) and 0, 1, or 2 carbon atoms (which can give rise to the bridging meso-carbons in hydroporphyrins). Carbon 233-240 small nuclear ribonucleoprotein polypeptide E Homo sapiens 102-105 17165790-2 2006 The present study shows that the enhancement of carbon acidity of alpha-amino acids by the cofactor pyridoxal 5"-phosphate (PLP) with an unusual, unprotonated pyridine is mainly due to solvation effects, in contrast to the intrinsic electron-withdrawing stabilization by the pyridinium ion to form a quinonoid intermediate. Carbon 48-54 pyridoxal phosphatase Homo sapiens 124-127 33387767-0 2021 Comprehensive analysis of SUSIBA2 rice: The low-methane trait and associated changes in soil carbon and microbial communities. Carbon 93-99 Sugar signaling in barley 2 Hordeum vulgare 26-33 33387767-9 2021 Compared with the wild type, SUSIBA2 rice significantly reduced soil organic carbon properties and the abundance of CH4-related microbes, and altered methanogenic and methanotrophic communities, indicating that SUSIBA2 rice released less carbon to the soil, which reduced CH4 production. Carbon 77-83 Sugar signaling in barley 2 Hordeum vulgare 29-36 33387767-9 2021 Compared with the wild type, SUSIBA2 rice significantly reduced soil organic carbon properties and the abundance of CH4-related microbes, and altered methanogenic and methanotrophic communities, indicating that SUSIBA2 rice released less carbon to the soil, which reduced CH4 production. Carbon 77-83 Sugar signaling in barley 2 Hordeum vulgare 211-218 33387767-9 2021 Compared with the wild type, SUSIBA2 rice significantly reduced soil organic carbon properties and the abundance of CH4-related microbes, and altered methanogenic and methanotrophic communities, indicating that SUSIBA2 rice released less carbon to the soil, which reduced CH4 production. Carbon 238-244 Sugar signaling in barley 2 Hordeum vulgare 29-36 33387767-9 2021 Compared with the wild type, SUSIBA2 rice significantly reduced soil organic carbon properties and the abundance of CH4-related microbes, and altered methanogenic and methanotrophic communities, indicating that SUSIBA2 rice released less carbon to the soil, which reduced CH4 production. Carbon 238-244 Sugar signaling in barley 2 Hordeum vulgare 211-218 17137358-5 2006 Both reactions are initiated by the nucleophilic attack of the methylene carbon of the MPIs to the carbon atom of the electrophilically activated BNOs. Carbon 73-79 nitric oxide synthase 1 Homo sapiens 146-150 33422879-0 2021 A flow injection fluorescence "turn-on" sensor for the determination of metformin hydrochloride based on the inner filter effect of nitrogen-doped carbon dots/gold nanoparticles double-probe. Carbon 147-153 SAFB like transcription modulator Homo sapiens 72-95 33422879-1 2021 In this paper, an ultrasensitive and rapid "turn-on" fluorescence sensor, integrating flow-injection (FI) with nitrogen-doped carbon dots/gold nanoparticles (N-CDs/AuNPs) double-probe is established for the determination of metformin hydrochloride (MET) in biological fluids. Carbon 126-132 SAFB like transcription modulator Homo sapiens 224-247 33422879-1 2021 In this paper, an ultrasensitive and rapid "turn-on" fluorescence sensor, integrating flow-injection (FI) with nitrogen-doped carbon dots/gold nanoparticles (N-CDs/AuNPs) double-probe is established for the determination of metformin hydrochloride (MET) in biological fluids. Carbon 126-132 SAFB like transcription modulator Homo sapiens 249-252 17137358-5 2006 Both reactions are initiated by the nucleophilic attack of the methylene carbon of the MPIs to the carbon atom of the electrophilically activated BNOs. Carbon 99-105 nitric oxide synthase 1 Homo sapiens 146-150 16842825-0 2006 Molecular and stable carbon isotopic characterization of PAH contaminants at McMurdo Station, Antarctica. Carbon 21-27 phenylalanine hydroxylase Homo sapiens 57-60 33831358-0 2021 Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells. Carbon 71-77 indoleamine 2,3-dioxygenase 1 Homo sapiens 17-21 33831358-4 2021 Tryptophan is a theoretical source of one-carbon units through metabolism by IDO1, an enzyme intensively investigated in the context of tumor immune evasion. Carbon 42-48 indoleamine 2,3-dioxygenase 1 Homo sapiens 77-81 33831358-6 2021 In IDO1-expressing cancer cells, tryptophan is a bona fide one-carbon donor for purine nucleotide synthesis in vitro and in vivo. Carbon 63-69 indoleamine 2,3-dioxygenase 1 Homo sapiens 3-7 33386486-5 2021 Here we show that such highly elevated A:T to C:G transversion mutations associated with uracil residues in DNA are abolished when apn1 yeast cells are grown in glucose as the primary carbon source. Carbon 185-191 DNA-(apurinic or apyrimidinic site) lyase APN1 Saccharomyces cerevisiae S288C 131-135 16949109-2 2006 The mutational effect and specificity of carbon-ion beams were studied in the URA3 gene of the yeast. Carbon 41-47 orotidine-5'-phosphate decarboxylase Saccharomyces cerevisiae S288C 78-82 33629724-5 2021 Carbon-fixing microbial populations using the Calvin-Benson-Bassham (CCB) pathway were widespread in the studied lakes, and they were dominated by the cbbL and cbbM gene types affiliated with Cyanobacteria and Proteobacteria, respectively. Carbon 0-6 opsin 1, medium wave sensitive Homo sapiens 160-164 33629724-6 2021 The cbbL and cbbM gene abundance and population structures were significantly affected by different environmental variables, with the cbbL and cbbM genes being negatively correlated with salinity and organic carbon concentration, respectively. Carbon 208-214 opsin 1, medium wave sensitive Homo sapiens 13-17 17441068-5 2006 The reaction of 3,5-Me2C6H3COCl with {(DB24C8)[4-H]}+ (PF6)- affords the organic rotaxane {(DB24C8)(4-tBuC6H4CH2NH2CH2-C6H4COOCOC6H3Me2-3,5)}+ (PF6)- through C-O bond formation between the aroyl group and the carboxylate ligand of the axis component. Carbon 23-24 sperm associated antigen 17 Homo sapiens 55-58 33629724-6 2021 The cbbL and cbbM gene abundance and population structures were significantly affected by different environmental variables, with the cbbL and cbbM genes being negatively correlated with salinity and organic carbon concentration, respectively. Carbon 208-214 opsin 1, medium wave sensitive Homo sapiens 143-147 33438321-0 2021 Single atom Ru doped CoP/CDs Nanosheets via Splicing of Carbon-Dots for Robust Hydrogen Production. Carbon 56-62 caspase recruitment domain family member 16 Homo sapiens 21-24 17441068-5 2006 The reaction of 3,5-Me2C6H3COCl with {(DB24C8)[4-H]}+ (PF6)- affords the organic rotaxane {(DB24C8)(4-tBuC6H4CH2NH2CH2-C6H4COOCOC6H3Me2-3,5)}+ (PF6)- through C-O bond formation between the aroyl group and the carboxylate ligand of the axis component. Carbon 23-24 sperm associated antigen 17 Homo sapiens 144-147 16832579-2 2006 In this work, the important role of Ras2p in metabolic regulation during growth on the non-fermentable carbon source glycerol is further investigated. Carbon 103-109 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 36-41 33709249-11 2021 In vivo activation of c-MCT-3 produced MCT-3. Carbon 9-10 solute carrier family 16 member 3 Homo sapiens 24-29 16832579-8 2006 The data therefore provide new evidence for the role of Ras2p as a powerful modulator of metabolism during growth on a non-fermentable carbon source. Carbon 135-141 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 56-61 33379099-0 2021 A simple and efficient Solid-Phase Microextraction - Gas Chromatography - Mass Spectrometry method for the determination of fragrance materials at ultra-trace levels in water samples using multi-walled carbon nanotubes as innovative coating. Carbon 202-208 gastrin Homo sapiens 53-56 16910661-1 2006 Nitrogen-carbon bond formation from coordinated dinitrogen has been observed upon addition of 2 equiv of PhNCO to the hafnocene dinitrogen complex, [(eta5-C5Me4H)2Hf]2(mu2,eta2,eta2-N2). Carbon 9-15 DNA polymerase iota Homo sapiens 172-176 33379103-0 2021 A 3D hydrogel based on chitosan and carbon dots for sensitive fluorescence detection of microRNA-21 in breast cancer cells. Carbon 36-42 microRNA 21 Homo sapiens 88-99 33379103-2 2021 Herein, we fabricated carbon dots-chitosan nanocomposite hydrogels via reacting carbon dots synthesized from various aldehyde precursors with chitosan after that functionalized with ssDNA probe for detection of microRNA-21 in MCF-7 cancer cells. Carbon 22-28 microRNA 21 Homo sapiens 211-222 33433336-5 2021 Approaches involving meta-omics clarified that anammox and a Lautropia-affiliated species in the phylum Proteobacteria can supply costly public goods for DSF-Secretor species via secondary messenger c-di-GMP regulator (Clp) after sensing DSF. Carbon 199-201 calmodulin like 3 Homo sapiens 219-222 16910661-1 2006 Nitrogen-carbon bond formation from coordinated dinitrogen has been observed upon addition of 2 equiv of PhNCO to the hafnocene dinitrogen complex, [(eta5-C5Me4H)2Hf]2(mu2,eta2,eta2-N2). Carbon 9-15 DNA polymerase iota Homo sapiens 177-181 16837010-10 2006 Furthermore, the poor prognosis of the R58Q patients may be associated with more severe diastolic dysfunction due to the slower off-rate of Ca(2+) from troponin C leading to longer force and [Ca(2+)] transients and increased Ca(2+) sensitivity of ATPase and force. Carbon 140-141 dynein axonemal heavy chain 8 Homo sapiens 247-253 33085182-3 2021 The present study demonstrates that, in addition to its utility as a precursor to heterocycle synthesis, carboxy-MIDA-boronate is an excellent in situ CO surrogate that is tolerant of reactive functionalities such as amines, alcohols, and carbon-based nucleophiles. Carbon 239-245 NADH:ubiquinone oxidoreductase complex assembly factor 7 Homo sapiens 113-117 33608784-2 2021 Using the provincial panel data in China"s industry from 2005 to 2015, this study applies the System Generalized Method of Moments (SYS-GMM) to explore the impacts of corruption and energy efficiency on industrial carbon emissions. Carbon 214-220 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 132-135 16673402-6 2006 The model also predicted that Tyr66 forms hydrogen bond with the phosphate moiety of PLP and interacts with the side chain attached to beta-carbon of the amino acid substrate. Carbon 140-146 pyridoxal phosphatase Homo sapiens 85-88 33679162-2 2021 Glassy carbon electrode was modified by electropolymerization of phenolphthalein (PP) monomer (poly(PP)/GCE) and the multiwalled carbon nanotubes (MWCNTs) was dropped on the surface. Carbon 7-13 aminomethyltransferase Homo sapiens 104-107 16847623-1 2006 Hemoglobin (Hb) was immobilized on a glassy carbon electrode (GCE) surface by konjac glucomannan (KGM). Carbon 44-50 glycine cleavage system protein H Homo sapiens 62-65 33045607-3 2021 In this study, the absorption coefficient (bap) of OC (bap,OC) in Beijing during a polluted winter was estimated on the basis of the combined measurements of black carbon (BC) size distribution and total aerosol bap (bap,meas). Carbon 164-170 prohibitin 2 Homo sapiens 43-46 33045607-3 2021 In this study, the absorption coefficient (bap) of OC (bap,OC) in Beijing during a polluted winter was estimated on the basis of the combined measurements of black carbon (BC) size distribution and total aerosol bap (bap,meas). Carbon 164-170 prohibitin 2 Homo sapiens 55-58 33045607-3 2021 In this study, the absorption coefficient (bap) of OC (bap,OC) in Beijing during a polluted winter was estimated on the basis of the combined measurements of black carbon (BC) size distribution and total aerosol bap (bap,meas). Carbon 164-170 prohibitin 2 Homo sapiens 55-58 33045607-3 2021 In this study, the absorption coefficient (bap) of OC (bap,OC) in Beijing during a polluted winter was estimated on the basis of the combined measurements of black carbon (BC) size distribution and total aerosol bap (bap,meas). Carbon 164-170 prohibitin 2 Homo sapiens 55-58 33567275-2 2021 Of note, multi-walled carbon nanotubes (MWCNTs), the highly representative products of nanotechnology, induce macrophage NLRP3 inflammasome activation and cause asbestosis-like pathogenesis. Carbon 22-28 NLR family, pyrin domain containing 3 Mus musculus 121-126 16831423-3 2006 In this study, we found that vinexin alpha as well as beta interacts with c-Abl mainly through the third SH3 domain, and that vinexin and c-Abl were colocalized at membrane ruffles in rat astrocytes. Carbon 65-66 ABL proto-oncogene 1, non-receptor tyrosine kinase Rattus norvegicus 76-79 33561155-11 2021 The highly intensified receptor interaction of BPC is attributable to the presence of an n-pi-pi-n conjugation system mediated through the >C = CCl2 double bond. Carbon 49-50 C-C motif chemokine ligand 2 Homo sapiens 144-148 33260019-7 2021 LPS stimulation upregulated IL-10, IL-8, and IL-6 expression and Poly I:C upregulated TLR 8 and TLR 9 expression. Carbon 72-73 toll-like receptor 9 Bos taurus 96-101 11542461-11 1983 The yields of cyanide and formaldehyde parallel the amino acid results, with yields of HCN and H2CO as high as 13% based on the carbon. Carbon 128-134 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 87-90 6664873-0 1983 Introduction of carbon substituents at C-2 position of purine nucleosides. Carbon 16-22 complement C2 Homo sapiens 39-42 6664873-1 1983 A series of new purine nucleosides which have carbon substituents at their C-2 position were synthesized by non-aqueous diazotization/deamination of 2-amino-6-chloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)purine (1) with isoamyl nitrite in aromatic solvents and by palladium-catalyzed alkynylation of 2-iodo-adenosine (4) with terminal alkynes. Carbon 46-52 complement C2 Homo sapiens 75-78 16857587-2 2006 Yeast acetyl-CoA synthetases (Acs1p and 2p) are exceptional, as they are important not only for carbon metabolism but also are shown here to supply the acetyl-CoA for histone acetylation by histone acetyltransferases (HATs). Carbon 96-102 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 30-35 33509226-7 2021 Metabolomics microarray analysis and transcriptome sequencing analysis revealed that GOLPH3L promotes central carbon metabolism in breast cancer by stabilizing the p53 suppressor SERPINE1. Carbon 110-116 serpin family E member 1 Homo sapiens 179-187 33210665-0 2021 Acid-etched Fe/Fe2O3 nanoparticles encapsulated into carbon cloth as a novel voltammetric sensor for the simultaneous detection of Cd2+ and Pb2. Carbon 53-59 CD2 molecule Homo sapiens 131-134 7159569-6 1982 T1 and NOE values of FA resonances were constant between the FA-2 carbon and olefinic region of each acyl chain and increased markedly for carbons near the chain terminus. Carbon 66-72 FA complementation group B Homo sapiens 61-65 29435895-3 2006 The principal and the most pronounced features of these phenolic constituents are the assembly of an isoprenyl substituent at C-3 of a flavone skeleton by closure of an ether bridge or a carbon-carbon linkage with the B ring of the skeleton, which may further rearrange into xanthone to produce various classes of natural products. Carbon 187-193 complement component 3 Mus musculus 126-129 7145716-2 1982 In all of the deoxy sugars examined, NT1 values for C-2" are significantly larger than the values for the remaining carbons. Carbon 116-123 complement C2 Homo sapiens 52-55 33480350-0 2022 Neurokinin-1 receptor antagonist reverses functional CNS alteration caused by combined gamma-rays and carbon nuclei irradiation. Carbon 102-108 tachykinin receptor 1 Rattus norvegicus 0-21 29435895-3 2006 The principal and the most pronounced features of these phenolic constituents are the assembly of an isoprenyl substituent at C-3 of a flavone skeleton by closure of an ether bridge or a carbon-carbon linkage with the B ring of the skeleton, which may further rearrange into xanthone to produce various classes of natural products. Carbon 194-200 complement component 3 Mus musculus 126-129 16572472-10 2006 Phosphorylation of previously unknown basic proteins UEP and Lci5 by specific redox-dependent protein kinase(s) in the photosynthetic membranes reveals the early response of green algae to limitation in the environmental inorganic carbon. Carbon 231-237 uncharacterized protein Chlamydomonas reinhardtii 61-65 32947097-0 2021 Scanty graphene-driven phase control and heteroatom functionalization of ZIF-67-derived CoP-draped N-doped carbon/graphene as a hybrid electrode for high-performance asymmetric supercapacitor. Carbon 107-113 caspase recruitment domain family member 16 Homo sapiens 88-91 33416435-1 2022 This study presents the design and test of a novel self-adaptive soft gripper, integrating pneumatic actuators and bistable carbon-fiber reinforced polymer laminates. Carbon 124-130 POC1 centriolar protein A Homo sapiens 65-69 6814427-3 1982 Acid ceramidase activities towards N-lauroyl- (C(12:0)), N-myristoyl- (C(14:0)) and N-palmitoyl- (C(16:0)) sphingosine (C(18:1)) were respectively about 38, 26 and 6 times higher than the activity towards the N-stearoyl (C(18:0)) substrate. Carbon 47-48 N-acylsphingosine amidohydrolase 1 Homo sapiens 0-15 6279450-6 1982 The glucose moieties of glucose 1-phosphate, glucose 6-phosphate and glucose 1,6-bisphosphate were degraded and showed that epididymal fat pad enzymes relocate 14C from [2-14C]glucose into C-1, C-2, and C-3 of each hexose-phosphate. Carbon 162-163 complement C2 Rattus norvegicus 194-197 7133987-3 1982 Calcium effects within the cell are mostly mediated through binding of the ion to low molecular weight proteins that form an evolutionary family including parvalbumin, calmodulin, troponin C, the alkali and regulatory light chains of myosin, the S-100 protein and the vitamin D-dependent intestinal calcium-binding protein. Carbon 0-1 myosin heavy chain 14 Homo sapiens 234-240 33390181-2 2021 We previously proved that CHKA down-modulation reduced OC cell aggressiveness and increased sensitivity to in vitro chemotherapeutics" treatment also affecting intracellular content of one-carbon metabolites. Carbon 189-195 choline kinase alpha Homo sapiens 26-30 16549685-8 2006 Taken together, these results suggest that Cdc25 is involved in the regulation of cell size in the presence of different carbon sources. Carbon 121-127 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 43-48 33520360-3 2021 We found that the migration and invasion was enhanced in DLD-1 cells but impaired in HCT116 cells in vitro and in vivo after radiation of gamma-rays or carbons, and radiation induced epithelial mesenchymal transition (EMT) in DLD-1 cells but mesenchymal epithelial transition (MET) in HCT116 cells. Carbon 152-159 SAFB like transcription modulator Homo sapiens 277-280 6282014-0 1982 [Carbon assimilation from a NaHCO3 nutrient medium by an STI-1 strain culture]. Carbon 1-7 stress induced phosphoprotein 1 Homo sapiens 57-62 16487345-9 2006 The only exception was following carbon starvation, where Gat1, like Gln3, is hyperphosphorylated in a Snf1-dependent manner. Carbon 33-39 Gat1p Saccharomyces cerevisiae S288C 58-62 32383312-4 2021 Here we report that Cystathionine beta-synthase (CBS), a central enzyme in one-carbon metabolism, functionally interacts with the core circadian protein Cryptochrome1 (CRY1). Carbon 79-85 cystathionine beta-synthase Mus musculus 20-47 32383312-4 2021 Here we report that Cystathionine beta-synthase (CBS), a central enzyme in one-carbon metabolism, functionally interacts with the core circadian protein Cryptochrome1 (CRY1). Carbon 79-85 cystathionine beta-synthase Mus musculus 49-52 16686191-0 2006 [Denitrification using PBS as carbon source and biofilm supporter: effect of pH]. Carbon 30-36 cholinergic receptor muscarinic 3 Homo sapiens 23-26 32383312-12 2021 We observed temporal variation in one-carbon and transsulfuration pathways attributable to CRY1 induced CBS activation. Carbon 38-44 cystathionine beta-synthase Mus musculus 104-107 32949949-2 2021 Technological progress greatly contributes to the promotion of carbon productivity (CP). Carbon 63-69 ceruloplasmin Homo sapiens 84-86 7317383-1 1981 Carbon isotope effects for the carbon atom arising from bicarbonate have been measured for the phosphoenolpyruvate carboxylase from maize. Carbon 0-6 MLO-like protein 4 Zea mays 95-126 7317383-1 1981 Carbon isotope effects for the carbon atom arising from bicarbonate have been measured for the phosphoenolpyruvate carboxylase from maize. Carbon 31-37 MLO-like protein 4 Zea mays 95-126 16686191-1 2006 PBS, a new kind of biodegradable polymers (BDPs), was used as carbon source and biofilm carrier to remove nitrate from drinking water. Carbon 62-68 cholinergic receptor muscarinic 3 Homo sapiens 0-3 6276836-2 1981 Calculations for various possible mixtures of CH4, CO2, CO, N2, H2, and H2O reveal that the prime species produced were probably HCN and NO and that the key parameter determining the rates of fixation was the ratio of C atoms to O atoms in the atmosphere. Carbon 0-1 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 129-132 33379337-8 2020 Tif51A expression followed dual positive regulation: by high glucose through TORC1 signalling, like other translation factors, to promote growth and by low glucose or non-fermentative carbon sources through Snf1 and heme-dependent transcription factor Hap1 to promote respiration. Carbon 184-190 translation elongation factor eIF-5A Saccharomyces cerevisiae S288C 0-6 16267870-4 2006 Aminolysis of 2,4-dinitrophenyl benzoate (1 c) results in a linear Bronsted-type plot with a beta(nuc) value of 0.40, suggesting that bond formation between the attacking amine and the carbonyl carbon atom of 1 c is little advanced in the transition state (TS). Carbon 185-191 nucleobindin 1 Homo sapiens 98-101 16423036-3 2006 Stimulation of HCECs with the TLR3 agonist poly(I:C) induced the activation of nuclear factor (NF)-kappaB and production of the proinflammatory cytokine interleukin (IL)-6 and the chemokine IL-8. Carbon 50-52 toll like receptor 3 Homo sapiens 30-34 10250470-2 1981 The NRC is amending its regulations to permit licensees greater leeway in disposing of liquid scintillation media and animal carcasses containing tracer levels of hydrogen-3 (tritium) or carbon-14. Carbon 187-193 nuclear receptor coactivator 6 Homo sapiens 4-7 10250470-6 1981 The NRC is also amending its regulations to raise the annual limits for disposal of hydrogen-3 and carbon-14 by release to the sanitary sewerage systems. Carbon 99-105 nuclear receptor coactivator 6 Homo sapiens 4-7 33313626-0 2020 Electrospun hetero-CoP/FeP embedded in porous carbon nanofibers: enhanced Na+ kinetics and specific capacity. Carbon 46-52 caspase recruitment domain family member 16 Homo sapiens 19-22 16316259-3 2005 Catalytic enantioselective cyanosilylation of ketone 13 produced the chiral tetrasubstituted carbon at C-8. Carbon 93-99 homeobox C8 Homo sapiens 103-106 33313626-3 2020 Herein, hetero-CoP/FeP nanoparticles embedded in porous carbon nanofibers (CoP/FeP@PCNFs) are obtained by coaxial electrospinning and low-temperature phosphorization processes. Carbon 56-62 caspase recruitment domain family member 16 Homo sapiens 75-78 32798857-6 2020 Building on our knowledge of abiotic Fe(II)-catalyzed mineralogical changes, the suppression of ferrihydrite transformation in FSi + Cl fractions in amended soils could ultimately lead to a slower turnover of ferrihydrite, possibly preserving the carbon sequestration potential associated with this mineral. Carbon 247-253 FIQTL1 Homo sapiens 127-130 33327675-5 1981 For a given temperature between 22 and 62 C, the 13 C-{1 H} NOE value is practically the same for seven protonated carbons (C2 , C8 , C1" , C2" , C3" , C4" , C5" ). Carbon 115-122 heterogeneous nuclear ribonucleoprotein C Homo sapiens 134-161 16150974-4 2005 The crystal structures of the unfluorinated and fluorinated wild-type MnSOD are nearly superimposable with the root mean-square deviation for 198 alpha-carbon atoms at 0.3 A. Carbon 152-158 superoxide dismutase 2 Homo sapiens 70-75 6169688-2 1981 The i-CAR-RR complex showed electron density on carbon layers. Carbon 48-54 CXADR pseudogene 1 Homo sapiens 6-9 33097153-9 2020 Sintering dust enhanced the adsorption and oxidation of NO, and activated carbon further promoted the reduction of NOx by NH3; thus, the denitrification efficiency increased by 5%-7% on the activated carbon. Carbon 74-80 NADPH oxidase Drosophila melanogaster 115-118 33097153-9 2020 Sintering dust enhanced the adsorption and oxidation of NO, and activated carbon further promoted the reduction of NOx by NH3; thus, the denitrification efficiency increased by 5%-7% on the activated carbon. Carbon 200-206 NADPH oxidase Drosophila melanogaster 115-118 7334427-6 1981 On the basis of the C-13 NMR spectrum, the signals assigned to two carbons (C1" and C-2") of the alcohol moiety of ethyl caffeate were observed clearly in F3. Carbon 67-74 heterogeneous nuclear ribonucleoprotein C Homo sapiens 76-79 16170208-5 2005 A minimum of a 12 carbon acyl chain was required for normal CERK activity, and the 4-5 trans double bond was important for substrate recognition. Carbon 18-24 ceramide kinase Homo sapiens 60-64 7397132-8 1980 The change of the positive sign to negative one at alpha-band of circular dichroism spectrum supports the hypothesis that the conversion of rhodopsin is due to rotation of the chromophoric retinal about C-11--12 double bond ("photoisomerization model"). Carbon 203-204 rhodopsin Bos taurus 140-149 33170611-0 2020 New Insights into Co-pyrolysis among Graphitic Carbon Nitride and Organic Compounds: Carbonaceous Gas Fragments Induced Synthesis of Ultrathin Mesoporous Nitrogen-Doped Carbon Nanosheets for Heterogeneous Catalysis. Carbon 47-53 gastrin Homo sapiens 98-101 32297512-7 2020 Accordingly, 3 reacts with an NHC nucleophile (IMe4) to yield the Lewis adduct [{(NHC)C(Ph)}P(IMe4)]Fe(CO)4 (5) (IMe4 = :C(NMeCMe)2). Carbon 32-33 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Homo sapiens 47-51 32297512-7 2020 Accordingly, 3 reacts with an NHC nucleophile (IMe4) to yield the Lewis adduct [{(NHC)C(Ph)}P(IMe4)]Fe(CO)4 (5) (IMe4 = :C(NMeCMe)2). Carbon 32-33 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Homo sapiens 94-98 16269214-10 2005 Collectively, our data indicate that alpha,beta unsaturation (and not a double bond in another position) is the most important structural determinant for PTP inhibition, the alkenal with 9-carbon atoms being the most effective in eliciting such inhibition. Carbon 189-195 protein tyrosine phosphatase receptor type U Homo sapiens 154-157 32297512-7 2020 Accordingly, 3 reacts with an NHC nucleophile (IMe4) to yield the Lewis adduct [{(NHC)C(Ph)}P(IMe4)]Fe(CO)4 (5) (IMe4 = :C(NMeCMe)2). Carbon 32-33 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Homo sapiens 94-98 33169998-3 2020 This study aims to explore and characterize, through density functional theory (DFT) calculations, covalent tip-functionalization of single-walled carbon nanotubes (SWCNTS) with carboxymethyl moieties that establish pH sensitive molecular gates. Carbon 147-153 TOR signaling pathway regulator Homo sapiens 108-111 16166091-2 2005 We have created a conditional knock-out model in which the administration of poly(I:C) caused a virtually total deletion of c/ebpalpha (C/EBPalpha(Delta/-) mice) in the liver, spleen, white and brown adipose tissues, pancreas, lung, and kidney of the mice. Carbon 84-85 CCAAT/enhancer binding protein (C/EBP), alpha Mus musculus 124-134 31072233-6 2020 Among the nitrogen-tailed carbons, HNO3-treated activated carbon (AC-N) showed the highest Vmic (0.127 cm3/g), the largest CO2 adsorption capacity (2.8 mmol/g at 273 K, 1 bar) and the best CO2/N2 selectivity as compared to urea and melamine treated ones. Carbon 66-70 complement C2 Homo sapiens 189-195 6103759-3 1980 Selectivity for the beta 2-adrenoceptor was improved with tertiary branching at the gamma-carbon and further increased by aromatic substitution with resorcinol or saligenin. Carbon 90-96 adrenoceptor beta 2 Rattus norvegicus 20-39 16166091-2 2005 We have created a conditional knock-out model in which the administration of poly(I:C) caused a virtually total deletion of c/ebpalpha (C/EBPalpha(Delta/-) mice) in the liver, spleen, white and brown adipose tissues, pancreas, lung, and kidney of the mice. Carbon 84-85 CCAAT/enhancer binding protein (C/EBP), alpha Mus musculus 136-146 6998654-1 1980 DBH is a copper-containing oxygenase that catalyzes the hydroxylation of the beta carbon of a wide variety of phenylethylamine derivatives using molecular oxygen ascorbate as cofactors. Carbon 82-88 dopamine beta-hydroxylase Homo sapiens 0-3 32061118-6 2020 Hence, repression of co293 expression elevates the levels of HcaR and FadR with consequent activation of alternative carbon catabolic pathways. Carbon 117-123 DNA-binding transcriptional dual regulator FadR Escherichia coli str. K-12 substr. MG1655 70-74 16075109-1 2005 Multi-stage mass spectrometry (MSn) on [(M + Ag - H)x + Ag]+ precursor ions (where M = an amino acid such as glycine or N,N-dimethylglycine) results in the formation of stable silver (Ag3+, Ag5+ and Ag7+) and silver hydride (Ag2H+, Ag4H+ and Ag6H+) cluster cations in the gas phase. Carbon 190-193 anterior gradient 3, protein disulphide isomerase family member Homo sapiens 184-187 7408842-5 1980 The measured values of the vicinal coupling constants between H-1" and the C-8 and C-4 carbons were employed to evaluate approximately the glycosidic angles chi of the nucleosides in the conformations syn and anti. Carbon 87-94 complement C4A (Rodgers blood group) Homo sapiens 83-86 15998011-0 2005 Weak carbon-hydrogen-nitrogen interactions affect the heterocyclic ligand bonding modes in barium complexes containing eta2-tetrazolato and eta2-pentazolato ligands. Carbon 5-11 DNA polymerase iota Homo sapiens 119-123 15998011-0 2005 Weak carbon-hydrogen-nitrogen interactions affect the heterocyclic ligand bonding modes in barium complexes containing eta2-tetrazolato and eta2-pentazolato ligands. Carbon 5-11 DNA polymerase iota Homo sapiens 140-144 316337-2 1979 Dissociation constants for the binding of alcohols to luciferase intermediate are in the order of K8 greater than K10 greater than K12 congruent to K14 where the subscripts represent the numbers of carbon atoms of various alcohols. Carbon 198-204 keratin 14 Homo sapiens 148-151 15949702-4 2005 By contrast, eta was mildly increased from 1.7389 +/- 0.07 in C to 1.8022 +/- 0.154 in LC and 1.9030 +/- 0.177 in LC+AH. Carbon 62-63 endothelin receptor type A Homo sapiens 13-16 43143-10 1979 Carbon atoms C-2, C-3 and C-4 of the acetoacetate produced were derived from the carbon skeleton of the 4-methyl-2-oxopentanoate, but the acetoacetate carboxy group was derived from the incorporation of CO2. Carbon 81-87 complement C2 Rattus norvegicus 13-21 15887969-6 2005 In addition, a NH group on the right side of carbonyl group of the amide pharmacophore substituted with an adamantyl group (such as compound 14) and a methylene carbon present between the adamantyl and amide groups were essential to produce potent inhibition of sEH. Carbon 45-51 epoxide hydrolase 2 Homo sapiens 262-265 486439-9 1979 Based on these results, it was infered that the formation of batho-rhodopsin is due to photoisomerization of the chromophoric retinal of rhodopsin and is not due to translocation of a proton on the ring or on the side chain from C-6 to C-8 of the chromophoric retinal to the Schiff-base nitrogen. Carbon 229-230 rhodopsin Bos taurus 67-76 227369-5 1979 During carbon-limited growth on methanol or succinate some cytochrome c was tightly bound to bacterial membranes, whereas none was tightly bound in bacteria grown in batch-culture or in NH(4) (+)-limited conditions. Carbon 7-13 MEXAM1_RS12150 Methylobacterium extorquens AM1 59-71 15941036-6 2005 Here, the CD2 rocking band data are used to determine the amount of gauche conformers at the deuterated carbon positions C-4 and C-6, and C-12. Carbon 104-110 complement C6 Homo sapiens 129-132 728380-5 1978 This structure can be generated from either rhodopsin or isorhodopsin by a similar motion (simultaneously rotating chromophore carbon atoms 10 and 11 out-of-plane). Carbon 127-133 rhodopsin Bos taurus 44-53 15941036-6 2005 Here, the CD2 rocking band data are used to determine the amount of gauche conformers at the deuterated carbon positions C-4 and C-6, and C-12. Carbon 10-11 complement C6 Homo sapiens 129-132 15866171-8 2005 Thus, AMPK is a cell-intrinsic regulator of the cell cycle that coordinates cellular proliferation with carbon source availability. Carbon 104-110 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 6-10 728538-5 1978 Changes in carbon-13 chemical shifts fro ribose C-5" (downfield), C-2" C-3", and C-4" (upfield) and for adenine C-6 and C-8 (upfield) support this model. Carbon 11-17 complement C5 Homo sapiens 48-51 15824785-5 2005 Treatment of 2 (R=Ph) with HCl at -40 degrees C affords five-coordinate [RhCl(C[triple bond, length as m-dash]CPh){(Z)-CH=CHPh}(PiPr3)2] 23, which at room temperature reacts by C-C coupling to give trans-[RhCl{eta2-(Z)-PhC[triple bond, length as m-dash]CCH=CHPh}(PiPr3)2](Z)-21. Carbon 28-29 DNA polymerase iota Homo sapiens 210-214 698301-2 1978 Butyrylcholine esterase found to increase the hydrolysis rate of all the alkaloid esters studied with the increase of acyl radical either to valerates (for ephedrine and pseudo-ephedrine derivatives), or to butyrates (for the rest alkaloids) and then it did not considerably change under further elongation of carbon chain up to valerate. Carbon 310-316 butyrylcholinesterase Homo sapiens 0-23 342498-5 1978 Colonies that grow with lactate, malate, or succinate as a carbon source in the presence of 0.5 to 2 mM 2-doexygalactose were found to be mostly galP mutants, lacking galactose permease. Carbon 59-65 galanin like peptide Homo sapiens 145-149 15751982-6 2005 Solid-state NMR methods were used to examine the size and heterogeneity of Ala-PLB and TM-Ala-PLB labeled with (13)C and (2)H in the transmembrane domain and incorporated into dimyristoylphosphatidylcholine (DMPC) bilayers. Carbon 115-116 phospholamban Homo sapiens 94-97 15721899-2 2005 The activated carbons were characterized by nitrogen adsorption, XRD, TGA and solubility tests. Carbon 14-21 T-box transcription factor 1 Homo sapiens 70-73 589799-0 1977 Assay of ornithine carbamoyltransferase activity in human liver using carbon-labeled ornithine and thin-layer chromatography. Carbon 70-76 ornithine transcarbamylase Homo sapiens 9-39 15721899-5 2005 Copper chloride on the activated carbon in a range of 3-20 wt% Cu content was present mostly in the amorphous form of CuCl(2), according to the results of the solubility, XRD and TGA tests. Carbon 33-39 T-box transcription factor 1 Homo sapiens 179-182 15551062-17 2005 Thus, the different affinity of ADH and ALDH for alcohols and glycol ethers of different carbon-chain length may reflect the relative isoform expression in rat liver and skin. Carbon 89-95 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 40-44 599577-1 1977 The effect of respiratory infection by PR8 influenza virus on the elution of bnezo[a]pyrene (BaP) from carbon particles in the respiratory tract of mice was studied. Carbon 103-109 prohibitin 2 Mus musculus 93-96 599577-3 1977 If BaP-coated carbon particles are introduced into the respiratory tract during the acute stage of infection, the rate of BaP elution from the carbon particles is increased. Carbon 14-20 prohibitin 2 Mus musculus 3-6 599577-3 1977 If BaP-coated carbon particles are introduced into the respiratory tract during the acute stage of infection, the rate of BaP elution from the carbon particles is increased. Carbon 14-20 prohibitin 2 Mus musculus 122-125 599577-3 1977 If BaP-coated carbon particles are introduced into the respiratory tract during the acute stage of infection, the rate of BaP elution from the carbon particles is increased. Carbon 143-149 prohibitin 2 Mus musculus 3-6 599577-3 1977 If BaP-coated carbon particles are introduced into the respiratory tract during the acute stage of infection, the rate of BaP elution from the carbon particles is increased. Carbon 143-149 prohibitin 2 Mus musculus 122-125 15721951-0 2005 Synthesis and bioactivity of C-29 brassinosteroid analogues with different functional groups at C-6. Carbon 29-30 complement C6 Homo sapiens 96-99 599577-4 1977 When BaP-coated carbon particles were instilled in the respiratory tract either 1 wk before or 2 wk after the acute stage of infection, the BaP elution rate from carbon particles were similar to that in uninfected animals. Carbon 16-22 prohibitin 2 Mus musculus 5-8 599577-4 1977 When BaP-coated carbon particles were instilled in the respiratory tract either 1 wk before or 2 wk after the acute stage of infection, the BaP elution rate from carbon particles were similar to that in uninfected animals. Carbon 16-22 prohibitin 2 Mus musculus 140-143 599577-4 1977 When BaP-coated carbon particles were instilled in the respiratory tract either 1 wk before or 2 wk after the acute stage of infection, the BaP elution rate from carbon particles were similar to that in uninfected animals. Carbon 162-168 prohibitin 2 Mus musculus 5-8 599577-4 1977 When BaP-coated carbon particles were instilled in the respiratory tract either 1 wk before or 2 wk after the acute stage of infection, the BaP elution rate from carbon particles were similar to that in uninfected animals. Carbon 162-168 prohibitin 2 Mus musculus 140-143 15683801-1 2005 Electrochemical redox processes of bovine heart cytochrome c were investigated by in situ UV-vis and CD spectroelectrochemistry at bare glassy carbon electrode (GCE) and single-wall carbon nanotubes (SWNTs) modified glassy carbon electrode (SWNTs/GCE) using a long optical path thin layer cell. Carbon 143-149 LOC104968582 Bos taurus 48-60 20173-6 1977 In the range of fibrin concentration(c) from 3 to 14 milligrams, v is approximately proportional to c-2 for clots of coarse structure and to c-0.5 for clots of fine structure. Carbon 23-24 complement C2 Homo sapiens 100-103 15683801-1 2005 Electrochemical redox processes of bovine heart cytochrome c were investigated by in situ UV-vis and CD spectroelectrochemistry at bare glassy carbon electrode (GCE) and single-wall carbon nanotubes (SWNTs) modified glassy carbon electrode (SWNTs/GCE) using a long optical path thin layer cell. Carbon 182-188 LOC104968582 Bos taurus 48-60 15683801-1 2005 Electrochemical redox processes of bovine heart cytochrome c were investigated by in situ UV-vis and CD spectroelectrochemistry at bare glassy carbon electrode (GCE) and single-wall carbon nanotubes (SWNTs) modified glassy carbon electrode (SWNTs/GCE) using a long optical path thin layer cell. Carbon 182-188 LOC104968582 Bos taurus 48-60 15680604-2 2005 The reactivity towards BCl(3) follows the order: C-4>or=C-2>C-6>C-3 for C-glucopyranosyl derivatives and C-3>or=C-4>C-6>C-2 for C-galactopyranosyl derivatives. Carbon 24-25 complement C6 Homo sapiens 66-69 332511-2 1977 Immunofluorescent and carbon particle ingestion techniques suggest that the erythropoietin was elaborated by macrophages or Kupffer cells of the hepatic reticuloendothelial system. Carbon 22-28 erythropoietin Mus musculus 76-90 328914-5 1977 The epoxide decomposes to form a carbonium ion at C-2, which attacks nucleophilic sites in DNA, especially on the guanine moiety. Carbon 33-42 complement C2 Homo sapiens 50-53 15680604-2 2005 The reactivity towards BCl(3) follows the order: C-4>or=C-2>C-6>C-3 for C-glucopyranosyl derivatives and C-3>or=C-4>C-6>C-2 for C-galactopyranosyl derivatives. Carbon 24-25 complement C6 Homo sapiens 131-134 15590633-7 2005 The data indicate that binding sites in three PDI domains, a, b", and a", contribute to efficient C-P4H tetramer assembly. Carbon 98-99 prolyl 4-hydroxylase subunit beta Homo sapiens 46-49 16659894-0 1977 Fractionation of stable carbon isotopes by phosphoenolpyruvate carboxylase from c(4) plants. Carbon 24-30 MLO-like protein 4 Zea mays 43-74 15965718-7 2005 These results suggest that the proportional utilization of PAH carbon to natural organic carbon is as much as three orders of magnitude higher during cooler months, when water temperatures are lower and DO % saturation is higher. Carbon 63-69 phenylalanine hydroxylase Homo sapiens 59-62 320197-1 1977 A new mutation introducing a one-carbon requirement (e.g., formate) for the glycine-supplemented growth of a serine-glycine auxotroph (ser1) was correlated with a lack of glycine decarboxylase activity. Carbon 33-39 O-phospho-L-serine:2-oxoglutarate transaminase Saccharomyces cerevisiae S288C 135-139 15965718-7 2005 These results suggest that the proportional utilization of PAH carbon to natural organic carbon is as much as three orders of magnitude higher during cooler months, when water temperatures are lower and DO % saturation is higher. Carbon 89-95 phenylalanine hydroxylase Homo sapiens 59-62 920454-1 1977 Rat liver microsomes contain a delta 6 desaturase that is active not only with the unsaturated acids of 18 carbons: oleic, linoleic and alpha-linolenic but also with similar acids of 20 carbons with the double bonds in delta 9, 12 and delta 12, 15. Carbon 107-114 fatty acid desaturase 2 Rattus norvegicus 31-49 18007286-3 2005 The fully interpreted (1)H- and (13)C-NMR spectra of the ArI(OAc)2 products are reported. Carbon 36-37 ariadne RBR E3 ubiquitin protein ligase 1 Homo sapiens 57-66 920454-1 1977 Rat liver microsomes contain a delta 6 desaturase that is active not only with the unsaturated acids of 18 carbons: oleic, linoleic and alpha-linolenic but also with similar acids of 20 carbons with the double bonds in delta 9, 12 and delta 12, 15. Carbon 186-193 fatty acid desaturase 2 Rattus norvegicus 31-49 15859417-2 2005 The results showed that advanced treatments using ultra-filtration and activated carbon absorption were suitable for removal of toxic organic substances from STP effluent. Carbon 81-87 sulfotransferase family 1A member 1 Homo sapiens 158-161 185197-2 1976 The argR mutant was found to excrete arginine into the growth medium with glycerol but not glucose as carbon source. Carbon 102-108 arginine repressor Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 4-8 15556357-9 2004 The detection limit of the biosensors produced by non-covalent immobilization of acetylcholinesterase onto polyethyleneimine modified carbon electrodes was found to be about 10(-10) M for the organophosphate pesticide dichlorvos. Carbon 134-140 Acetylcholine esterase Drosophila melanogaster 81-101 15584735-9 2004 The IR spectra for the carbon monoxide (CO) complex of the reconstituted myoglobin suggest several structural and/or electrostatic conformations of the Fe-C-O bond, but this is not directly correlated with the CO dissociation rate. Carbon 40-41 myoglobin Physeter catodon 73-82 1244926-0 1976 Increased erythropoietin production in anephric rats with hyperplasia of the reticuloendothelial system induced by colloidal carbon or zymosan. Carbon 125-131 erythropoietin Rattus norvegicus 10-24 15290295-14 2004 The results suggest that the increased remobilization of carbon reserves by water stress is attributable to the enhanced FEH and SPS activities in wheat stems, and that ABA plays a vital role in the regulation of the key enzymes involved in fructan and sucrose metabolism. Carbon 57-63 beta-fructofuranosidase, insoluble isoenzyme 4 Triticum aestivum 121-124 970695-4 1976 It catalyses the transformation into ketone of the secondary alcohol group at the 3 beta position of sterols which possess in the C17 position a lateral chain of at least two carbon atoms. Carbon 175-181 cytokine like 1 Homo sapiens 130-133 15488475-0 2004 C-25 hydroxylation of 1alpha,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1): metabolism studies with human keratinocytes and rat recombinant CYP24A1. Carbon 0-1 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 182-189 171253-0 1975 Reduced nicotinamide adenine dinucleotide-activated phosphoenolpyruvate carboxylase in Pseudomonas MA: potential regulation between carbon assimilation and energy production. Carbon 132-138 phosphoenolpyruvate carboxykinase 1 Homo sapiens 52-83 171253-1 1975 Comparison of enzyme activities in crude extracts of methylamine-grown Pseudomonas MA (ATCC 23319) to those in succinate-grown cells indicates the involvement of an acetyl coenzyme A-independent phosphoenolpyruvate carboxylase in one-carbon metabolism. Carbon 234-240 phosphoenolpyruvate carboxykinase 1 Homo sapiens 195-226 765685-1 1975 The activity and electrophoretic spectrum of glucose-6-phosphate dehydrogenase, alcohol dehydrogenase, and malate dehydrogenase in Saccharomyces cerevisiae 14 depended on the conditions of cultivation, i. e. the sources of carbon and their concentration, the content of nitrogen, and aeration of the medium. Carbon 223-229 glucose-6-phosphate dehydrogenase Saccharomyces cerevisiae S288C 45-78 1159711-3 1975 [The C-17 position is the carbon attached to C-8 of the ergoline (1) skeleton as indicated in structure 2.] Carbon 26-32 cytokine like 1 Homo sapiens 5-9 15501181-2 2004 In plants, Fru-2,6-P(2) coordinates the photosynthetic carbon flux into sucrose and starch biosynthesis. Carbon 55-61 zinc finger and BTB domain containing 22 Homo sapiens 11-14 169239-5 1975 Numerous single carbon resonances are observed in the aromatic regions of 13C NMR spectra of cytochrome c, lysozyme, and myoglobin. Carbon 16-22 cytochrome c, somatic Equus caballus 93-105 167712-2 1975 A soluble enzyme system which oxidizes benzene to cis-1,2-dihydroxycyclohexa-3,5-diene (cis-benzene glycol) was obtained from a species of Pseudomonas grown on benzene as the major carbon source. Carbon 181-187 suppressor of cytokine signaling 1 Homo sapiens 50-55 15297456-7 2004 Whereas UNG expression is significantly higher in proliferating as compared with nonproliferating cells, such as neurons, the levels of UNG mRNA were increased in brains of cystathionine beta-synthase knockout mice, a model for hyperhomocysteinemia, suggesting that one-carbon metabolism impairment and uracil misincorporation can induce the up-regulation of UNG expression. Carbon 270-276 uracil DNA glycosylase Mus musculus 136-139 4365619-0 1974 Specific induction of transitions and transversions of G-C base pairs by 4-nitroquinoline-1-oxide in iso-1-cytochrome c mutants of yeast. Carbon 57-58 threonine ammonia-lyase ILV1 Saccharomyces cerevisiae S288C 101-106 4796394-2 1973 Stereoselective labelling at C-2 of tyramine: stereochemistry of hydroxylation at saturated carbon. Carbon 92-98 complement C2 Homo sapiens 29-32 15297456-7 2004 Whereas UNG expression is significantly higher in proliferating as compared with nonproliferating cells, such as neurons, the levels of UNG mRNA were increased in brains of cystathionine beta-synthase knockout mice, a model for hyperhomocysteinemia, suggesting that one-carbon metabolism impairment and uracil misincorporation can induce the up-regulation of UNG expression. Carbon 270-276 uracil DNA glycosylase Mus musculus 136-139 32910708-12 2020 After irradiations with protons of the mid SOBP, carbon ions of the pristine and slightly widened Bragg peak RBE ranges for HTB140 cells from 2.08, 4.81 to 7.06, for MCF-7 from 1.70, 3.28 to 4.17, for HTB177 from 1.98, 4.18 to 5.08 and for CRL5876 from 1.33, 2.57 to 3.51.Conclusion: Significant elimination of HTB140 cells is observed along the carbon Bragg curve. Carbon 49-55 sine oculis binding protein homolog Homo sapiens 43-47 15543751-0 2004 Addition of carbon sorbents to reduce PCB and PAH bioavailability in marine sediments: physicochemical tests. Carbon 12-18 phenylalanine hydroxylase Homo sapiens 46-49 5101784-3 1971 Making certain stoichiometric assumptions about the oxidation of the C-1 and C-6 carbons of glucose to CO(2), the data are incorporated into a multicompartmental model describing the kinetics of plasma glucose, plasma bicarbonate, and the conversion of glucose to CO(2) by the hexose monophosphate pathway and all other series and parallel pathways which oxidize glucose carbon to CO(2) (EMP-TCA). Carbon 81-88 heterogeneous nuclear ribonucleoprotein C Homo sapiens 69-80 5101784-3 1971 Making certain stoichiometric assumptions about the oxidation of the C-1 and C-6 carbons of glucose to CO(2), the data are incorporated into a multicompartmental model describing the kinetics of plasma glucose, plasma bicarbonate, and the conversion of glucose to CO(2) by the hexose monophosphate pathway and all other series and parallel pathways which oxidize glucose carbon to CO(2) (EMP-TCA). Carbon 81-87 heterogeneous nuclear ribonucleoprotein C Homo sapiens 69-80 15555906-0 2004 The cationic charges on Arg347, Arg358 and Arg449 of human cytochrome P450c17 (CYP17) are essential for the enzyme"s cytochrome b5-dependent acyl-carbon cleavage activities. Carbon 146-152 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 59-77 5669849-13 1968 It is proposed that d-glucose is the ideal structure for active transport and that binding occurs at C-1, C-2, C-3, C-4 and C-6. Carbon 106-107 complement C6 Rattus norvegicus 124-127 5669849-13 1968 It is proposed that d-glucose is the ideal structure for active transport and that binding occurs at C-1, C-2, C-3, C-4 and C-6. Carbon 106-107 complement C6 Rattus norvegicus 124-127 5669849-13 1968 It is proposed that d-glucose is the ideal structure for active transport and that binding occurs at C-1, C-2, C-3, C-4 and C-6. Carbon 106-107 complement C6 Rattus norvegicus 124-127 32604523-0 2020 Growing Properties of Carbon Nanowalls According to the Hydrogen Gas Ratio. Carbon 22-28 gastrin Homo sapiens 65-68 32887166-0 2020 Carbon dots-based fluorescence resonance energy transfer for the prostate specific antigen (PSA) with high sensitivity. Carbon 0-6 kallikrein related peptidase 3 Homo sapiens 65-90 32887166-0 2020 Carbon dots-based fluorescence resonance energy transfer for the prostate specific antigen (PSA) with high sensitivity. Carbon 0-6 kallikrein related peptidase 3 Homo sapiens 92-95 15555906-0 2004 The cationic charges on Arg347, Arg358 and Arg449 of human cytochrome P450c17 (CYP17) are essential for the enzyme"s cytochrome b5-dependent acyl-carbon cleavage activities. Carbon 146-152 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 79-84 15555906-1 2004 CYP17 (17alpha-hydroxylase-17,20-lyase; also P450c17 or P450(17alpha)) catalyses the17alpha-hydroxylation of progestogens and the subsequent acyl-carbon cleavage of the 17alpha-hydroxylated products (lyase activity) in the biosynthesis of androgens. Carbon 146-152 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 0-5 15555906-1 2004 CYP17 (17alpha-hydroxylase-17,20-lyase; also P450c17 or P450(17alpha)) catalyses the17alpha-hydroxylation of progestogens and the subsequent acyl-carbon cleavage of the 17alpha-hydroxylated products (lyase activity) in the biosynthesis of androgens. Carbon 146-152 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 45-52 33066660-0 2020 Response of Palladium and Carbon Nanotube Composite Films to Hydrogen Gas and Behavior of Conductive Carriers. Carbon 26-32 gastrin Homo sapiens 70-73 15555906-4 2004 In the present study it was found that substitution of human CYP17 amino acids, Arg(347), Arg(358) and Arg(449), with non-cationic residues, yielded variants that were impaired in the two acyl-carbon bond cleavage activities, quantitatively to the same extent and these were reduced to between 3 and 4% of the wild-type protein. Carbon 193-199 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 61-66 33050324-7 2020 Furthermore, activation of IRF3 by polyinosinic-polycytidylic acid (poly I:C) produced a cooperative effect with TNF-alpha for MIP-1alpha/CCL3 production that was comparable to stearic acid. Carbon 75-76 C-C motif chemokine ligand 3 Homo sapiens 127-137 15991400-3 2004 A model of the interaction between target molecules and the polymer-carbon black composite sensors is under development to aid in selecting the array members and to enable identification of compounds with responses not stored in the analysis library. Carbon 68-74 activation induced cytidine deaminase Homo sapiens 123-126 33050324-7 2020 Furthermore, activation of IRF3 by polyinosinic-polycytidylic acid (poly I:C) produced a cooperative effect with TNF-alpha for MIP-1alpha/CCL3 production that was comparable to stearic acid. Carbon 75-76 C-C motif chemokine ligand 3 Homo sapiens 138-142 32845949-5 2020 The complex RU1 shows potential to consume H2O2 from the one carbon metabolism in mitochondria, and hence may cut the energy cycle pathway of tumor cells. Carbon 61-67 Scm like with four mbt domains 1 Homo sapiens 12-15 17830485-1 1967 A new polymorph of carbon, hexagonal diamond, has been discovered in the Canyon Diablo and Goalpara meteorites. Carbon 19-25 diablo IAP-binding mitochondrial protein Homo sapiens 80-86 33215508-12 2021 Meanwhile, overexpression of duck TLR3 significantly promoted the transcription of IFN-beta, IRF7, TRIF, Mx, STAT1 and STAT2 mRNA after stimulation with poly(I:C). Carbon 160-162 interferon regulatory factor 7 Anas platyrhynchos 93-97 33215508-12 2021 Meanwhile, overexpression of duck TLR3 significantly promoted the transcription of IFN-beta, IRF7, TRIF, Mx, STAT1 and STAT2 mRNA after stimulation with poly(I:C). Carbon 160-162 Signal transducer and activator of transcription 1-alpha/beta Anas platyrhynchos 109-114 33450645-1 2021 An electrochemical deposition method was used to fabricate a gold nanoflower (AuNF) and carbon nanoparticle (CNP) modified carbon paper (CP) sensor (AuNFs-CNPs/CP) for the low-cost detection of 5-methyltetrahydrofolate (5-mTHF) in egg yolk. Carbon 88-94 ceruloplasmin Homo sapiens 137-139 33450645-1 2021 An electrochemical deposition method was used to fabricate a gold nanoflower (AuNF) and carbon nanoparticle (CNP) modified carbon paper (CP) sensor (AuNFs-CNPs/CP) for the low-cost detection of 5-methyltetrahydrofolate (5-mTHF) in egg yolk. Carbon 88-94 ceruloplasmin Homo sapiens 160-162 33450645-1 2021 An electrochemical deposition method was used to fabricate a gold nanoflower (AuNF) and carbon nanoparticle (CNP) modified carbon paper (CP) sensor (AuNFs-CNPs/CP) for the low-cost detection of 5-methyltetrahydrofolate (5-mTHF) in egg yolk. Carbon 123-129 ceruloplasmin Homo sapiens 137-139 32924514-3 2020 Herein, we report the design and preparation of nitrogen-doped carbon dots functionalized with atomically dispersed copper centers by Cu-N coordination (Cu/NCD) that exhibit apparent antibacterial activity towards Gram-negative Escherichia coli (E. coli) under photoirradiation. Carbon 63-69 protein K Escherichia coli 134-138 15296789-2 2004 The first case was realized with a solution containing p-methylamino-phenolsulphate (MAP) as redox mediator and the diaphorase (DI) from Clostridium kluveri as enzyme while the second one by using both a glassy carbon (GC) and a carbon nanotube paste (CNTP) electrode modified with electrodeposited films derived from 3,4-dihydroxybenzaldehyde (3,4-DHB). Carbon 211-217 dihydrolipoamide dehydrogenase Homo sapiens 116-126 33036195-4 2020 Gene deletion of peroxiredoxins in wine yeasts indicate that TSA1, thioredoxins and thioredoxin reductase TRR1 are required for normal growth in medium with glucose and sucrose as carbon sources. Carbon 180-186 thioredoxin peroxidase TSA1 Saccharomyces cerevisiae S288C 61-65 33036195-4 2020 Gene deletion of peroxiredoxins in wine yeasts indicate that TSA1, thioredoxins and thioredoxin reductase TRR1 are required for normal growth in medium with glucose and sucrose as carbon sources. Carbon 180-186 thioredoxin-disulfide reductase TRR1 Saccharomyces cerevisiae S288C 106-110 34029588-7 2021 Following this observation, a proteomic screen of the viperin interactome identified several cholesterol biosynthetic enzymes among the top hits, including lanosterol synthase (LS) and squalene monooxygenase (MS), which are enzymes that catalyze key steps in establishing the sterol carbon skeleton. Carbon 283-289 lanosterol synthase Homo sapiens 156-175 33036136-5 2020 Titanium dioxide was used as an ion storage layer and a carbon containing dispersion was used for the counter electrode on a polyester rip-stop fabric. Carbon 56-62 receptor interacting serine/threonine kinase 1 Homo sapiens 135-138 15296789-2 2004 The first case was realized with a solution containing p-methylamino-phenolsulphate (MAP) as redox mediator and the diaphorase (DI) from Clostridium kluveri as enzyme while the second one by using both a glassy carbon (GC) and a carbon nanotube paste (CNTP) electrode modified with electrodeposited films derived from 3,4-dihydroxybenzaldehyde (3,4-DHB). Carbon 211-217 dihydrolipoamide dehydrogenase Homo sapiens 128-130 34052536-0 2021 A novel worm-like micelles@MOFs precursor for constructing hierarchically porous CoP/N-doped carbon networks towards efficient hydrogen evolution reaction. Carbon 93-99 caspase recruitment domain family member 16 Homo sapiens 81-84 34052536-2 2021 Hierarchically porous cobalt phosphide/N-doped nanotubular carbon networks (CoP/NCNs) that have all the features were fabricated in this work. Carbon 59-65 caspase recruitment domain family member 16 Homo sapiens 76-79 32497919-2 2020 Here, we design and fabricate a highly efficient electrocatalyst with unique three-dimensional (3D) porous peony-like micro-flower Mn-CoP nano-structure on flexible carbon cloth (Mn-CoP PMFs/CC), which exhibits high electrocatalytic activity toward the HER in both acid and alkaline circumstances. Carbon 165-171 caspase recruitment domain family member 16 Homo sapiens 134-137 15296789-2 2004 The first case was realized with a solution containing p-methylamino-phenolsulphate (MAP) as redox mediator and the diaphorase (DI) from Clostridium kluveri as enzyme while the second one by using both a glassy carbon (GC) and a carbon nanotube paste (CNTP) electrode modified with electrodeposited films derived from 3,4-dihydroxybenzaldehyde (3,4-DHB). Carbon 229-235 dihydrolipoamide dehydrogenase Homo sapiens 116-126 32497919-2 2020 Here, we design and fabricate a highly efficient electrocatalyst with unique three-dimensional (3D) porous peony-like micro-flower Mn-CoP nano-structure on flexible carbon cloth (Mn-CoP PMFs/CC), which exhibits high electrocatalytic activity toward the HER in both acid and alkaline circumstances. Carbon 165-171 caspase recruitment domain family member 16 Homo sapiens 182-185 15296789-2 2004 The first case was realized with a solution containing p-methylamino-phenolsulphate (MAP) as redox mediator and the diaphorase (DI) from Clostridium kluveri as enzyme while the second one by using both a glassy carbon (GC) and a carbon nanotube paste (CNTP) electrode modified with electrodeposited films derived from 3,4-dihydroxybenzaldehyde (3,4-DHB). Carbon 229-235 dihydrolipoamide dehydrogenase Homo sapiens 128-130 32926059-2 2020 In this work, the ZIF-67-derived CoP quantum dot (QD) anchored graphitized carbon skeleton as a co-catalyst is loaded on CdS nanorods (NRs), while the CoP QDs derived from ZIF-67 are anchored to the carbon skeleton under phosphation and carbonization simultaneously. Carbon 75-81 caspase recruitment domain family member 16 Homo sapiens 33-36 15570978-1 2004 Characteristics of carbon deposition by CH4 and carbon elimination by CO2 over conventional and nanoscale Ni/gamma-Al2O3 catalysts were investigated by using a pulse reaction, as well as by TGA, TEM, TPO-MS, H2-TPR and H2-chemisorption techniques. Carbon 19-25 T-box transcription factor 1 Homo sapiens 190-193 32926059-2 2020 In this work, the ZIF-67-derived CoP quantum dot (QD) anchored graphitized carbon skeleton as a co-catalyst is loaded on CdS nanorods (NRs), while the CoP QDs derived from ZIF-67 are anchored to the carbon skeleton under phosphation and carbonization simultaneously. Carbon 75-81 caspase recruitment domain family member 16 Homo sapiens 151-154 32926059-2 2020 In this work, the ZIF-67-derived CoP quantum dot (QD) anchored graphitized carbon skeleton as a co-catalyst is loaded on CdS nanorods (NRs), while the CoP QDs derived from ZIF-67 are anchored to the carbon skeleton under phosphation and carbonization simultaneously. Carbon 199-205 caspase recruitment domain family member 16 Homo sapiens 33-36 32926059-3 2020 The porous, graphitized carbon skeleton can not only disperse CoP QDs, increasing active sites for the hydrogen reduction reaction, but also provide electron transfer channels, promoting electron transfer and increasing conductivity. Carbon 24-30 caspase recruitment domain family member 16 Homo sapiens 62-65 32930692-1 2020 Carbon-rich ruthenium allenylidene complexes bearing either a hexaarylbenzene (HAB) or a hexa-peri-hexabenzocoronene (HBC) substituent were synthesised. Carbon 0-6 hexosaminidase subunit alpha Homo sapiens 62-66 34052536-6 2021 In the CoP/NCNs, there are plentiful CoP nanoparticles embedded on the surface of conductive carbon network and fully exposed. Carbon 93-99 caspase recruitment domain family member 16 Homo sapiens 7-10 34052536-6 2021 In the CoP/NCNs, there are plentiful CoP nanoparticles embedded on the surface of conductive carbon network and fully exposed. Carbon 93-99 caspase recruitment domain family member 16 Homo sapiens 37-40 33949397-2 2021 The different halogen atoms connected with the middle carbon atom result in the varied strength of C-X (X = F, Cl, Br) bonds, and thus different thermal stability of these agents, which could further affect the pyrolysis mechanism/products and the fire-extinguishing mechanism/performance of these agents. Carbon 54-60 chromosome 12 open reading frame 73 Homo sapiens 115-117 33985221-0 2021 Relationships between optical backscattering, particulate organic carbon, and phytoplankton carbon in the oligotrophic South China Sea basin. Carbon 92-98 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 131-134 15246081-1 2004 An efficient chiron approach for the synthesis of bicyclic diazasugars 4a and 4b having both -CH(2)OH and -OH functionality at the same carbon atom (C-6) is reported. Carbon 136-142 complement C6 Homo sapiens 149-152 33960656-3 2021 One carbon homologations aided by reactions at the unsaturated moiety expand the molecular structures in both endo- and exocyclic sugars and lead to structures that are largely hitherto unknown. Carbon 4-10 mannosidase endo-alpha Homo sapiens 110-114 32895691-5 2020 In contrast, mixed clusters, where HCCH is preferentially ionized over HCN, can grow up to 3 or 4 units long with new carbon-carbon and carbon-nitrogen covalent bonds. Carbon 118-124 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 71-74 32895691-5 2020 In contrast, mixed clusters, where HCCH is preferentially ionized over HCN, can grow up to 3 or 4 units long with new carbon-carbon and carbon-nitrogen covalent bonds. Carbon 125-131 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 71-74 32895691-5 2020 In contrast, mixed clusters, where HCCH is preferentially ionized over HCN, can grow up to 3 or 4 units long with new carbon-carbon and carbon-nitrogen covalent bonds. Carbon 125-131 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 71-74 33792090-2 2021 In this work, the tailoring of electronic structure of Pt single atoms supported on N-doped mesoporous hollow carbon spheres (Pt1 /NMHCS) via strong EMSI engineering is reported. Carbon 110-116 zinc finger protein 77 Homo sapiens 126-129 15316652-3 2004 The importance of Acs has been recognized for decades, since it provides the cell the two-carbon metabolite used in many anabolic and energy generation processes. Carbon 90-96 acyl-CoA synthetase short chain family member 2 Homo sapiens 18-21 33615540-0 2021 Estrogen-related receptor gamma increases poly(I:C)-mediated type I IFN expression in mouse macrophages. Carbon 49-51 estrogen-related receptor gamma Mus musculus 0-31 32948038-4 2020 The test results showed that the strengthening effect of sticking carbon fiber-reinforced polymer (CFRP) sheets is better than that of sticking CFRP bars or steel bars due to the better bonding conditions; therefore, the lap joint reinforced with CFRP sheets was further analyzed using a numerical approach. Carbon 66-72 LAP Homo sapiens 221-224 15316652-5 2004 In eukaryotes and prokaryotes, complex regulatory systems control acs gene expression as a function carbon flux, with a second layer of regulation exerted posttranslationally by the NAD+/sirtuin-dependent protein acetylation/deacetylation system. Carbon 100-106 acyl-CoA synthetase short chain family member 2 Homo sapiens 66-69 32667728-1 2020 Rhodium PC carbene P complexes 1-L {L = PPh 3 , PPh 2 (C 6 F 5 )} react with iso -thiocyanate, carbodiimide and disulphide to enable C-S, C-N and S-S bond cleavage. Carbon 9-10 protein phosphatase 4 catalytic subunit Homo sapiens 40-45 15261542-1 2004 Activated carbons with a high BET surface area and a well-developed porosity have been prepared from pyrolysis of H3PO4-impregnated lignin precipitated from kraft black liquors. Carbon 10-17 delta/notch like EGF repeat containing Homo sapiens 30-33 33042991-12 2020 Cit2p is part of the glyoxylate cycle, which is required for the production of essential carbohydrates when yeast is grown on non-fermentable carbon sources. Carbon 142-148 citrate (Si)-synthase CIT2 Saccharomyces cerevisiae S288C 0-5 32533616-2 2020 They are bicyclic octapeptides with a central quaternary carbon atom (avionin), which is installed through the cooperative action of the class-III lanthipeptide synthetase MicKC and the cysteine decarboxylase MicD. Carbon 57-63 MHC class I polypeptide-related sequence D (pseudogene) Homo sapiens 209-213 33547664-5 2021 AtALT1 and AtALT4 overexpression in leaves and seeds resulted in the accumulation of 12-14 carbon-length fatty acids and 6-8 carbon-length fatty acids, respectively. Carbon 91-98 Thioesterase superfamily protein Arabidopsis thaliana 0-6 15161308-7 2004 In tetrahydrofuran only N-metalated mixed LiCH(2)CN dimers were observed for both Li-1 and Li-2 with the less shielded (13)C NMR shifts of delta -2.5 and -2.2 for the alpha-carbon of LiCH(2)CN of the complexes. Carbon 173-179 transglutaminase 1 Homo sapiens 82-86 33550059-0 2021 Faunal and environmental drivers of carbon and nitrogen cycling along a permeability gradient in shallow North Sea sediments. Carbon 36-42 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 111-114 32914228-0 2020 Utilizing a nanocomposite consisting of zinc ferrite, copper oxide, and gold nanoparticles in the fabrication of a metformin electrochemical sensor supported on a glassy carbon electrode. Carbon 170-176 SAFB like transcription modulator Homo sapiens 115-124 15161308-7 2004 In tetrahydrofuran only N-metalated mixed LiCH(2)CN dimers were observed for both Li-1 and Li-2 with the less shielded (13)C NMR shifts of delta -2.5 and -2.2 for the alpha-carbon of LiCH(2)CN of the complexes. Carbon 173-179 ATP binding cassette subfamily A member 12 Homo sapiens 91-95 15293458-4 2004 The activated carbon nanoparticles and PYM were mixed with saline and shaken 20 minutes so that PYM was absorbed on activated carbon enough, resulting in a new formulation of PYM (PYM-CH-NP). Carbon 14-20 PYM homolog 1, exon junction complex associated factor Homo sapiens 96-99 33013787-11 2020 The carbon isotopic signature indicated pedogenic carbonates (delta13Cav = -8.2 +- 5.0%) formed when dolerite was applied and carbon originating from urea (delta13Cav = -46.4 +- 1.0%) precipitated when CaCl2 was used. Carbon 4-10 caveolin 2 Homo sapiens 69-72 33013787-11 2020 The carbon isotopic signature indicated pedogenic carbonates (delta13Cav = -8.2 +- 5.0%) formed when dolerite was applied and carbon originating from urea (delta13Cav = -46.4 +- 1.0%) precipitated when CaCl2 was used. Carbon 50-56 caveolin 2 Homo sapiens 69-72 32776397-4 2020 The abundant strong polar C-F bonds in the upper carbon can not only act as Li+ capture site to pre-uniform Li+ flux but also regulate the electron configuration of LiF to make Li+ quasi-spontaneously diffuse from carbon to LiF surface, avoiding the strong Li+ -adhesion-induced Li aggregation. Carbon 49-55 LIF interleukin 6 family cytokine Homo sapiens 165-168 33876814-6 2021 This review examines recent studies of both experiments and theoretical modeling of gas hydrates within four categories of nanoporous material hosts that include porous carbons, metal-organic frameworks, graphene nanoslits, and carbon nanotubes. Carbon 169-176 gastrin Homo sapiens 84-87 33876814-6 2021 This review examines recent studies of both experiments and theoretical modeling of gas hydrates within four categories of nanoporous material hosts that include porous carbons, metal-organic frameworks, graphene nanoslits, and carbon nanotubes. Carbon 169-175 gastrin Homo sapiens 84-87 32776397-4 2020 The abundant strong polar C-F bonds in the upper carbon can not only act as Li+ capture site to pre-uniform Li+ flux but also regulate the electron configuration of LiF to make Li+ quasi-spontaneously diffuse from carbon to LiF surface, avoiding the strong Li+ -adhesion-induced Li aggregation. Carbon 49-55 LIF interleukin 6 family cytokine Homo sapiens 224-227 15293458-4 2004 The activated carbon nanoparticles and PYM were mixed with saline and shaken 20 minutes so that PYM was absorbed on activated carbon enough, resulting in a new formulation of PYM (PYM-CH-NP). Carbon 14-20 PYM homolog 1, exon junction complex associated factor Homo sapiens 96-99 32776397-4 2020 The abundant strong polar C-F bonds in the upper carbon can not only act as Li+ capture site to pre-uniform Li+ flux but also regulate the electron configuration of LiF to make Li+ quasi-spontaneously diffuse from carbon to LiF surface, avoiding the strong Li+ -adhesion-induced Li aggregation. Carbon 214-220 LIF interleukin 6 family cytokine Homo sapiens 165-168 32776397-4 2020 The abundant strong polar C-F bonds in the upper carbon can not only act as Li+ capture site to pre-uniform Li+ flux but also regulate the electron configuration of LiF to make Li+ quasi-spontaneously diffuse from carbon to LiF surface, avoiding the strong Li+ -adhesion-induced Li aggregation. Carbon 214-220 LIF interleukin 6 family cytokine Homo sapiens 224-227 33925077-0 2021 Fabrication of Carbon Nanomaterials Using Laser Scribing on Copper Nanoparticles-Embedded Polyacrylonitrile Films and Their Application in a Gas Sensor. Carbon 15-21 gastrin Homo sapiens 141-144 33925077-7 2021 In addition, the fabricated gas sensor consists of carbon materials and quartz with excellent thermal stability; therefore, it is expected to operate as a gas sensor even in extreme environments. Carbon 51-57 gastrin Homo sapiens 28-31 15293458-4 2004 The activated carbon nanoparticles and PYM were mixed with saline and shaken 20 minutes so that PYM was absorbed on activated carbon enough, resulting in a new formulation of PYM (PYM-CH-NP). Carbon 14-20 PYM homolog 1, exon junction complex associated factor Homo sapiens 180-189 33925077-7 2021 In addition, the fabricated gas sensor consists of carbon materials and quartz with excellent thermal stability; therefore, it is expected to operate as a gas sensor even in extreme environments. Carbon 51-57 gastrin Homo sapiens 155-158 15293458-4 2004 The activated carbon nanoparticles and PYM were mixed with saline and shaken 20 minutes so that PYM was absorbed on activated carbon enough, resulting in a new formulation of PYM (PYM-CH-NP). Carbon 126-132 PYM homolog 1, exon junction complex associated factor Homo sapiens 96-99 33891343-3 2021 Herein, we report a one-step scalable template/solvent-free pyrolysis approach for in-situ immobilizing uniform CoP nanoparticles onto N and P co-doped carbon porous nanosheets (denoted as CoP@N,P-CNSs hereafter). Carbon 152-158 caspase recruitment domain family member 16 Homo sapiens 112-115 32498824-1 2020 The application of chitosan coated magnetite nanoparticle modified carbon paste electrode as a working electrode (chitosan@Fe3O4/CPE) for Cr(VI) analysis is presented. Carbon 67-73 carboxypeptidase E Homo sapiens 129-132 15293458-4 2004 The activated carbon nanoparticles and PYM were mixed with saline and shaken 20 minutes so that PYM was absorbed on activated carbon enough, resulting in a new formulation of PYM (PYM-CH-NP). Carbon 126-132 PYM homolog 1, exon junction complex associated factor Homo sapiens 96-99 15293458-4 2004 The activated carbon nanoparticles and PYM were mixed with saline and shaken 20 minutes so that PYM was absorbed on activated carbon enough, resulting in a new formulation of PYM (PYM-CH-NP). Carbon 126-132 PYM homolog 1, exon junction complex associated factor Homo sapiens 180-189 32872479-0 2020 Oriented Carbon Nanostructures from Plasma Reformed Resorcinol-Formaldehyde Polymer Gels for Gas Sensor Applications. Carbon 9-15 gastrin Homo sapiens 93-96 15293458-5 2004 The absorbency of PYM on activated carbon nanoparticles was evaluated. Carbon 35-41 PYM homolog 1, exon junction complex associated factor Homo sapiens 18-21 15293458-7 2004 The proportion of CH-NP to PYM was increased and more absorbency of PYM on activated carbon nanoparticles was achieved. Carbon 85-91 PYM homolog 1, exon junction complex associated factor Homo sapiens 68-71 15293458-8 2004 CONCLUSION: The activated carbon nanoparticles has high absorbency of PYM. Carbon 26-32 PYM homolog 1, exon junction complex associated factor Homo sapiens 70-73 32662629-4 2020 After investigating several C-M-S structures, the SERS blocking mechanism is validated that thick shells (Au, Ag, ZnO and MnO2) can cause significant reduction for the internal SERS signal by obstructing the penetration of the laser or signal. Carbon 28-29 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 50-54 32662629-4 2020 After investigating several C-M-S structures, the SERS blocking mechanism is validated that thick shells (Au, Ag, ZnO and MnO2) can cause significant reduction for the internal SERS signal by obstructing the penetration of the laser or signal. Carbon 28-29 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 177-181 15148401-3 2004 Here, we present the crystal structure of the key intermediate in the hydroxylation reaction of xanthine oxidoreductase with a slow substrate, in which the carbon-oxygen bond of the product is formed, yet the product remains complexed to the molybdenum. Carbon 156-162 xanthine dehydrogenase Homo sapiens 96-119 32824595-3 2020 Of the various TLR ligands examined, the TLR3-specific ligand polyinosinic:polycytidylic acid (poly I:C), significantly induced TNF production and the upregulation of other TLR transcripts, in particular, TLR2. Carbon 102-103 toll-like receptor 3 Mus musculus 41-45 32806560-4 2020 The C-S bond formation is carried out under palladium catalysis with the thiolate formed in situ resulting in high yields of tert-butyl aryl sulfides. Carbon 4-5 telomerase reverse transcriptase Homo sapiens 125-129 32796716-0 2020 Sirt1-PPARS Cross-Talk in Complex Metabolic Diseases and Inherited Disorders of the One Carbon Metabolism. Carbon 88-94 bone morphogenetic protein receptor type 2 Homo sapiens 18-22 33872517-0 2021 Stepping on the Gas to a Circular Economy: Accelerating Development of Carbon-Negative Chemical Production from Gas Fermentation. Carbon 71-77 gastrin Homo sapiens 16-19 33872517-0 2021 Stepping on the Gas to a Circular Economy: Accelerating Development of Carbon-Negative Chemical Production from Gas Fermentation. Carbon 71-77 gastrin Homo sapiens 112-115 33872517-3 2021 Gas fermentation using carbon-fixing microorganisms offers an economically viable and scalable solution with unique feedstock and product flexibility that has been commercialized recently. Carbon 23-29 gastrin Homo sapiens 0-3 33856105-2 2021 Based upon the recognition of latent symmetry within D-ring, our convergent synthesis features two critical reactions: (1) a symmetry-breaking, diastereoselective dearomative alkylation to assemble the entire carbon core, and (2) a Sc(OTf) 3 -mediated sequential Krapcho dealkoxycarbonylation/carbonyl alpha- tert -alkylation to forge the intricate bicyclo[3.3.1]nonane framework. Carbon 209-215 POU class 5 homeobox 1 Homo sapiens 232-241 33921475-5 2021 We found that co-culture of iDCs with differentially activated LAD2 MCs in serum-containing media significantly modulated polyinosinic:polycytidylic acid (poly I:C)-elicited DC maturation as determined through the surface expression of the maturation markers CD80, CD83, CD86, and human leukocyte antigen(HLA)-DR. Once iDCs were generated in serum-free conditions, they became refractory to the maturation with poly I:C, and the LAD2 MC modulatory potential was minimized. Carbon 30-31 CD83 molecule Homo sapiens 265-269 33611192-6 2021 The molecular modeling illustrated that compound DC-K2in212 had the similar binding mode with CDK2 as C-73, the most selective CDK2 inhibitor reported so far, which might account for selectivity against CDK2 over CDK1. Carbon 50-51 cyclin dependent kinase 1 Homo sapiens 213-217 15971617-2 2004 Catalase activity reached 1594 u/mL when the culture was grown on a complex carbon source containing 20 g/L dextrin and 1% (V/V) ethanol, which was 23% higher than the sum produced on 20 g/L dextrin and 1% (V/V) ethanol, respectively. Carbon 76-82 catalase Bos taurus 0-8 33797855-2 2021 Ucc1p of S. cerevisiae inhibits activation of the glyoxylate pathway by targeting Cit2p, a key glyoxylate enzyme for ubiquitin-mediated proteasomal degradation when glucose is available as a carbon source. Carbon 191-197 citrate (Si)-synthase CIT2 Saccharomyces cerevisiae S288C 82-87 33386486-0 2021 The activity of yeast Apn2 AP endonuclease at uracil-derived AP sites is dependent on the major carbon source. Carbon 96-102 DNA-(apurinic or apyrimidinic site) lyase APN2 Saccharomyces cerevisiae S288C 22-26 32779379-0 2021 Exposure to environmental black carbon exacerbates nasal epithelial inflammation via the reactive oxygen species (ROS)-nucleotide-binding, oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3)-caspase-1-interleukin 1beta (IL-1beta) pathway. Carbon 32-38 interleukin 1 alpha Homo sapiens 247-255 32676629-3 2020 Analysis of the voltammetric data in light of Marcus-Hush formulation reveals that the electro-reductive cleavage of the C-Cl bond of CCl4 over GCE in [BMIM][NTf2] follows a sticky dissociative electron transfer (SDET) pathway. Carbon 121-122 C-C motif chemokine ligand 4 Homo sapiens 134-138 32999530-4 2020 We find ToEs are robust across ESMs for sea surface temperature and the invasion of anthropogenic carbon; emergence time scales are 20-30 yr. For the biological carbon pump, and sea surface chlorophyll and salinity, emergence time scales are longer (50+ yr), less robust across the ESMs, and more sensitive to the forcing scenario considered. Carbon 98-104 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 178-181 32999530-4 2020 We find ToEs are robust across ESMs for sea surface temperature and the invasion of anthropogenic carbon; emergence time scales are 20-30 yr. For the biological carbon pump, and sea surface chlorophyll and salinity, emergence time scales are longer (50+ yr), less robust across the ESMs, and more sensitive to the forcing scenario considered. Carbon 161-167 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 40-43 15098205-5 2004 Under the optimum conditions, the calibration curve is linear over the range 3.75 x 10(-8) g/mL-1.5 x 10(-5) g/mL for tetracycline with the linear equation: deltaINT = 205.898 x C - 20.442 (R2 = 0.9974). Carbon 178-179 skull morphology 22 Mus musculus 93-99 32645209-2 2020 In this experiment, a new kind of electrochemical sensor is prepared based on magnetic mesoporous hollow carbon microspheres (MHM) as a penicillinase (Pen X) adsorption carrier to rapidly detect penicillin sodium (Pen G), named Pen X/MHM/MGCE. Carbon 105-111 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 151-154 32645209-2 2020 In this experiment, a new kind of electrochemical sensor is prepared based on magnetic mesoporous hollow carbon microspheres (MHM) as a penicillinase (Pen X) adsorption carrier to rapidly detect penicillin sodium (Pen G), named Pen X/MHM/MGCE. Carbon 105-111 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 214-217 32645209-2 2020 In this experiment, a new kind of electrochemical sensor is prepared based on magnetic mesoporous hollow carbon microspheres (MHM) as a penicillinase (Pen X) adsorption carrier to rapidly detect penicillin sodium (Pen G), named Pen X/MHM/MGCE. Carbon 105-111 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 214-217 33848949-0 2021 Separation of C1/C3 binary organic gas mixtures via flexible nanoporous carbon molecular sieves: DFT calculations and MD simulations. Carbon 72-78 heterogeneous nuclear ribonucleoprotein C Homo sapiens 14-19 33848949-1 2021 The C1/C3 hydrocarbon gas separation characteristics of nanoporous carbon molecular sieves (CMS) are studied using DFT calculations and MD simulations. Carbon 15-21 heterogeneous nuclear ribonucleoprotein C Homo sapiens 4-9 15268544-5 2004 In contrast, the reactivity of atomic oxygen with alkanethiolate SAMs is initiated at the vacuum/film interface, producing oxygen-containing carbon functional groups. Carbon 141-147 methionine adenosyltransferase 1A Homo sapiens 65-69 32970618-0 2020 Modeling the removal of Reactive Red 120 dye from aqueous effluents by activated carbon. Carbon 81-87 RNA binding motif protein 25 Homo sapiens 33-40 32970618-1 2020 The adsorption isotherms of Reactive Red 120 (RR-120) on Brazilian pine-fruit shell activated carbon, at six temperatures (298, 303, 308, 313, 318 and 323 K) and pH = 6, were determined and interpreted using a double layer model with one energy. Carbon 94-100 RNA binding motif protein 25 Homo sapiens 37-44 32970625-1 2020 The application of activated carbon fiber supported nanoscale zero-valent iron (ACF-nZVI) in the continuous removal of Cr(VI) and methyl orange (MO) from aqueous solution was studied in depth. Carbon 29-35 ACF Homo sapiens 80-83 14758298-9 2004 The carbon-fiber plate functions like the spring-steel shank within the sole of the shoe. Carbon 4-10 SH3 and multiple ankyrin repeat domains 2 Homo sapiens 55-60 32644783-0 2020 Mechanical Insights into the Enzymatic Cleavage of Double C-C Bond in Poly(cis-1,4-isoprene) by the Latex Clearing Protein. Carbon 39-40 suppressor of cytokine signaling 1 Homo sapiens 75-80 32644783-0 2020 Mechanical Insights into the Enzymatic Cleavage of Double C-C Bond in Poly(cis-1,4-isoprene) by the Latex Clearing Protein. Carbon 58-59 suppressor of cytokine signaling 1 Homo sapiens 75-80 32353788-8 2020 Comparing with reported activated carbon and resin materials, the UiO-66-NMe3+ MOFs possessed higher adsorption capacity and shorter equilibrium time, as well as good reusability and practicality. Carbon 34-40 NME/NM23 nucleoside diphosphate kinase 3 Homo sapiens 73-77 33750980-12 2021 The SD1 were negatively correlated to soil pH, hydrogen (H+), potassium (K+) and carbon (C). Carbon 81-87 CUP2Q35 Homo sapiens 4-7 33750980-12 2021 The SD1 were negatively correlated to soil pH, hydrogen (H+), potassium (K+) and carbon (C). Carbon 89-90 CUP2Q35 Homo sapiens 4-7 15137640-1 2004 Carbon nanotubes prepared by catalytic chemical vapor deposition of hydrocarbon at 650 degrees C show good adsorption capability of Pb2+, Cu2+ and Cd2+ ions from aqueous solution after oxidized with concentrated nitric acid at 140 degrees C for 1 h. The specific surface area and particle size distribution of the as-grown and oxidized CNTs were studied by BET method and laser particle analyzer. Carbon 0-6 delta/notch like EGF repeat containing Homo sapiens 357-360 32350077-7 2020 We noted that the growth of mpo1 cells is delayed upon carbon deprivation, suggesting that the Mpo1-mediated conversion of 2-OH FAs to non-hydroxy FAs is important for utilizing 2-OH FAs as a carbon source under carbon starvation. Carbon 56-62 Mpo1p Saccharomyces cerevisiae S288C 28-32 32350077-7 2020 We noted that the growth of mpo1 cells is delayed upon carbon deprivation, suggesting that the Mpo1-mediated conversion of 2-OH FAs to non-hydroxy FAs is important for utilizing 2-OH FAs as a carbon source under carbon starvation. Carbon 56-62 Mpo1p Saccharomyces cerevisiae S288C 96-100 33752360-3 2021 Here, we study the effect of interconnections on gas adsorption in materials with spherical pores, such as three-dimensionally ordered mesoporous (3DOm) carbons. Carbon 153-160 gastrin Homo sapiens 49-52 15499659-2 2004 The main reason for this might be that monosaccharides have to be derivatized prior to gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS) analyses and that a large isotopic correction is necessary for the carbon that has to be added to the original molecule during derivatization, resulting in large uncertainty of the calculated delta13C values of individual monosaccharides. Carbon 228-234 guanylate cyclase 2C Homo sapiens 150-154 33715163-0 2021 Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 Negatively Regulates Carbon Starvation Responses. Carbon 62-68 far-red elongated hypocotyls 3 Arabidopsis thaliana 12-40 33715163-7 2021 We thus concluded that the light signaling proteins FHY3 and FAR1 negatively regulate carbon-starvation responses in Arabidopsis. Carbon 86-92 far-red elongated hypocotyls 3 Arabidopsis thaliana 52-56 33715163-7 2021 We thus concluded that the light signaling proteins FHY3 and FAR1 negatively regulate carbon-starvation responses in Arabidopsis. Carbon 86-92 FRS (FAR1 Related Sequences) transcription factor family Arabidopsis thaliana 61-65 32350077-7 2020 We noted that the growth of mpo1 cells is delayed upon carbon deprivation, suggesting that the Mpo1-mediated conversion of 2-OH FAs to non-hydroxy FAs is important for utilizing 2-OH FAs as a carbon source under carbon starvation. Carbon 193-199 Mpo1p Saccharomyces cerevisiae S288C 28-32 32350077-7 2020 We noted that the growth of mpo1 cells is delayed upon carbon deprivation, suggesting that the Mpo1-mediated conversion of 2-OH FAs to non-hydroxy FAs is important for utilizing 2-OH FAs as a carbon source under carbon starvation. Carbon 193-199 Mpo1p Saccharomyces cerevisiae S288C 96-100 32350077-7 2020 We noted that the growth of mpo1 cells is delayed upon carbon deprivation, suggesting that the Mpo1-mediated conversion of 2-OH FAs to non-hydroxy FAs is important for utilizing 2-OH FAs as a carbon source under carbon starvation. Carbon 193-199 Mpo1p Saccharomyces cerevisiae S288C 28-32 32350077-7 2020 We noted that the growth of mpo1 cells is delayed upon carbon deprivation, suggesting that the Mpo1-mediated conversion of 2-OH FAs to non-hydroxy FAs is important for utilizing 2-OH FAs as a carbon source under carbon starvation. Carbon 193-199 Mpo1p Saccharomyces cerevisiae S288C 96-100 15484774-7 2004 SEM and BET tests of the carbon along with the culturing process were used to identify, respectively, the biofilm development and biocarbon porosity. Carbon 25-31 delta/notch like EGF repeat containing Homo sapiens 8-11 32504419-3 2020 By using a previously established mouse model of depression induced by combined delivery of IFN-alpha and polyinosinic:polycytidylic acid (poly(I:C)), a TLR3 agonist, we provide evidence that IFN-alpha and poly(I:C) reduce apical dendritic spine density in the hippocampal CA1 area ex vivo via mechanisms involving decreased TrkB signaling. Carbon 146-147 toll-like receptor 3 Mus musculus 153-157 31865509-8 2020 Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space. Carbon 194-195 K+ efflux antiporter 1 Arabidopsis thaliana 131-135 33661427-10 2021 Collectively, the results of the study reveal key insights into how landfill ageing and stabilisation influence distinct functional shifts in the abundance of GP and GN bacteria, and these are mainly driven by changes in C and N bioavailability. Carbon 0-1 ring finger protein 130 Homo sapiens 159-161 33168978-5 2021 We found that TLAM inhibits phosphofructokinase-1 (PFK1), which in turn activates AMPK-mediated fatty-acid oxidation to promote oxidative phosphorylation, and redirects carbon flow from glycolysis toward the pentose phosphate pathway to reinforce anti-oxidative potential. Carbon 169-175 phosphofructokinase, muscle Homo sapiens 28-49 33168978-5 2021 We found that TLAM inhibits phosphofructokinase-1 (PFK1), which in turn activates AMPK-mediated fatty-acid oxidation to promote oxidative phosphorylation, and redirects carbon flow from glycolysis toward the pentose phosphate pathway to reinforce anti-oxidative potential. Carbon 169-175 phosphofructokinase, muscle Homo sapiens 51-55 32610498-1 2020 The emergence and development of car sharing can not only satisfy people"s diverse travel demands, but also can bring a new solution to facilitate urban low-carbon and green development. Carbon 157-163 CXADR pseudogene 1 Homo sapiens 33-36 15626683-6 2004 Some physiological factors, such as carbon sources, phytohormones, affect directly or indirectly the expression and actions of LFY gene. Carbon 36-42 floral meristem identity control protein LEAFY (LFY) Arabidopsis thaliana 127-130 32575619-7 2020 Therefore, we describe the reprogramming of the central carbon metabolism associated with the IDH1 mutation in a genetically engineered mouse model which reflects the tumor biology encountered in glioma patients. Carbon 56-62 isocitrate dehydrogenase 1 (NADP+), soluble Mus musculus 94-98 14643231-4 2003 Next, the TPD results for D43/1 carbons (initial, modified with HNO(3), fuming H(2)SO(4), and with NH(3)) are described. Carbon 32-39 leiomodin 1 Homo sapiens 26-31 32536088-12 2020 WES sequencing and Sanger sequencing showed compound heterozygous LoF mutations in SRD5A2 [NM_000348.3:C.679C>T(p.Arg227Ter) and NM_000348.3:C.16C>T(p.Gln6Ter)] in this patient. Carbon 103-104 steroid 5 alpha-reductase 2 Homo sapiens 83-89 32536088-14 2020 Conclusion: Novel compound heterozygous LoF mutations in SRD5A2[NM_000348.3:C.679C>T(p.Arg227Ter) and NM_000348.3:C.16C>T(p.Gln6Ter)] may be the primary cause of disorders of sex development. Carbon 0-1 steroid 5 alpha-reductase 2 Homo sapiens 57-63 32503144-4 2020 The ULBP2 antibody was immobilized onto the screen-printed carbon electrode (SPCE) surfaces of three different sensors: a simple SPCE (ULBP2-SPCE); an SPCE array, which is a series of identical SPCE connected to each other at different arrangements of rows and columns (ULBP2-SPCE-1x2 and ULBP2-SPCE-1x3); and an SPCE combined with ZnO nanoparticles (ULBP2-ZnO/SPCE). Carbon 59-65 UL16 binding protein 2 Homo sapiens 4-9 33345397-1 2021 The high rates of photosynthesis and the carbon concentrating mechanism (CCM) in C4 plants is initiated by the enzyme phosphoenolpyruvate (PEP) carboxylase (PEPC). Carbon 41-47 phosphoenolpyruvate carboxykinase 1 Homo sapiens 118-155 33221014-11 2021 Total amounts of C, P, K and total nutrients returned to the topsoil in KF were significantly lower than those in NKF. Carbon 17-18 arylformamidase Homo sapiens 72-74 14605216-4 2003 Brassinosteroid feeding experiments with wild-type Arabidopsis, a CYP72B1 null mutant, and a CYP72B1 overexpression line demonstrated that carbon 26 hydroxylation of active brassinosteroids is an endogenous function of CYP72B1. Carbon 139-145 Cytochrome P450 superfamily protein Arabidopsis thaliana 66-73 31532899-5 2021 In this Review, the recent progresses in terms of surface and interface engineering of Mox C-based electrocatalytic materials are summarized, including the increased number of active sites by decreasing the particle size or introducing porous or hierarchical structures and surface modification by introducing heteroatom(s), defects, carbon materials, and others electronic conductive species. Carbon 334-340 monooxygenase DBH like 1 Homo sapiens 87-90 32841189-13 2020 There was a significant decrease in uric acid concentration, pro- (IL-1beta, TNF-alpha) and anti-inflammatory cytokine (IL-10) content after treatment in both groups, but more in patients who received carbon enterosorbent with basic therapy. Carbon 201-207 interleukin 1 alpha Homo sapiens 67-75 14605216-4 2003 Brassinosteroid feeding experiments with wild-type Arabidopsis, a CYP72B1 null mutant, and a CYP72B1 overexpression line demonstrated that carbon 26 hydroxylation of active brassinosteroids is an endogenous function of CYP72B1. Carbon 139-145 Cytochrome P450 superfamily protein Arabidopsis thaliana 93-100 31765755-7 2020 The human alpha-glucosidase (C-terminal maltase-glucoamylase, GH31) was used in the molecular docking analysis to determine the interaction of eriocitrin and eriodictyol with the alpha-glucosidase. Carbon 29-30 sucrase-isomaltase Homo sapiens 10-27 31765755-7 2020 The human alpha-glucosidase (C-terminal maltase-glucoamylase, GH31) was used in the molecular docking analysis to determine the interaction of eriocitrin and eriodictyol with the alpha-glucosidase. Carbon 29-30 sucrase-isomaltase Homo sapiens 179-196 33605070-3 2021 In this work, high loading Pt single atoms on graphitic carbon nitride (g-C3 N4 )-derived N-doped carbon nanosheets (Pt1 /NCNS) is achieved through atomic layer deposition. Carbon 56-62 zinc finger protein 77 Homo sapiens 117-120 14605216-4 2003 Brassinosteroid feeding experiments with wild-type Arabidopsis, a CYP72B1 null mutant, and a CYP72B1 overexpression line demonstrated that carbon 26 hydroxylation of active brassinosteroids is an endogenous function of CYP72B1. Carbon 139-145 Cytochrome P450 superfamily protein Arabidopsis thaliana 93-100 14627733-3 2003 The distribution of the C-C and C-S torsion angles (chi(3)) correlates well with the Boltzmann factor of the torsion energy, exp(-betaE) of the model compounds C(2)H(5)-C(2)H(5) and C(2)H(5)-S-CH(3). Carbon 24-25 muscleblind like splicing regulator 1 Homo sapiens 125-128 33603190-5 2021 In this study, we further demonstrate that CLEC18A and its mutant CLEC18A(S339R) associate with TLR3 in endosome and bind poly (I:C) specifically. Carbon 43-44 toll-like receptor 3 Mus musculus 96-100 33669424-7 2021 The revolution of integrating developed novel nanomaterials such as nanoparticles, carbon nanotubes, nanofibers and activated carbon, in polymers, have instigated revitalizing and favourable inventive nanotechnologies for the treatment of wastewater and gas separation. Carbon 126-132 gastrin Homo sapiens 254-257 32479562-7 2020 Here we show that long-term cultures of mutants expressing Coq8-A197V produce spontaneous revertants with the ability to grow on medium containing a non-fermentable carbon source. Carbon 165-171 protein kinase COQ8 Saccharomyces cerevisiae S288C 59-63 14623055-9 2003 We conclude that COX-2 in cancer cells is responsible for PGE(2) and OC production in cocultures with MMT060562, while COX-2 in bone marrow cells, not cancer cells, is responsible for PGE(2) and OC production in cocultures with BALB/c-MC, and EP4 receptors are essential for OC formation in both cocultures. Carbon 3-4 prostaglandin-endoperoxide synthase 2 Mus musculus 17-22 32456360-1 2020 Tests on a double lap bonded joint, with transverse strips of randomly oriented carbon nanotubes (CNT) sprayed onto an epoxy adhesive film, showed a positive increment in electrical resistance under tensile load, even though the transverse strains were negative. Carbon 80-86 LAP Homo sapiens 18-21 32443416-3 2020 In vitro, increased TNF-alpha and IL-1ss cytokine mRNA expression was observed in Nano-11-KAg-poly(I:C)-treated porcine monocyte-derived dendritic cells. Carbon 101-103 interleukin 1 alpha Homo sapiens 34-38 33623839-4 2021 Transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS) experiments confirm that CT-1 is composed of quasi-spherical nano-TiO2 and CQDs with a crystal plane of graphitic carbon. Carbon 196-202 cardiotrophin 1 Homo sapiens 107-111 14615977-10 2003 The results may be interpreted in the context of a model in which the halide order affects the rate of carbon-halogen bond cleavage of all such reactions catalyzed by the GSTs. Carbon 103-109 glutathione S-transferase theta 1 Rattus norvegicus 171-175 33307079-11 2021 In conclusion, the soil sorption capacity of DEP and Cd2+ was affected by biochar type, application dose and soil organic carbon content. Carbon 122-128 CD2 molecule Sus scrofa 53-56 32832049-9 2020 These facts, combined with the poor RTA activity we observe for a QMD with a stronger central C-C bond, support mechanism 4. Carbon 94-95 MAS related GPR family member F Homo sapiens 36-39 32832049-9 2020 These facts, combined with the poor RTA activity we observe for a QMD with a stronger central C-C bond, support mechanism 4. Carbon 96-97 MAS related GPR family member F Homo sapiens 36-39 14527463-2 2003 The relationships between the textural characteristics of carbon samples and the recovery rates (eta) of explosives on solid-phase extraction (SPE) using different solvents for their elution after adsorption were analyzed using experimental and quantum chemical calculation results. Carbon 58-64 endothelin receptor type A Homo sapiens 97-100 32405339-3 2020 We assessed whether increased one-carbon metabolism activity is a metabolic feature of invasive ductal carcinoma (IDC). Carbon 34-40 lamin A/C Homo sapiens 114-117 32405339-7 2020 Our targeted metabolomics analysis showed distinct metabolomics profiles between IDC and adjacent tissue, where IDC displayed a comparative enrichment of metabolites involved in one-carbon metabolism (serine, glycine, threonine, and methionine) and a predicted increase in the activity of pathways that receive and donate carbon units (i.e., folate, methionine, and homocysteine). Carbon 182-188 lamin A/C Homo sapiens 112-115 32405339-7 2020 Our targeted metabolomics analysis showed distinct metabolomics profiles between IDC and adjacent tissue, where IDC displayed a comparative enrichment of metabolites involved in one-carbon metabolism (serine, glycine, threonine, and methionine) and a predicted increase in the activity of pathways that receive and donate carbon units (i.e., folate, methionine, and homocysteine). Carbon 322-328 lamin A/C Homo sapiens 112-115 32405339-9 2020 The gene set enrichment analysis identified different transcription-related functions between IDC and non-tumor tissues that involved one-carbon metabolism. Carbon 138-144 lamin A/C Homo sapiens 94-97 32405339-10 2020 Our data suggest that one-carbon metabolism may be a central pathway in IDC and even in general breast tumors, representing a potential target for its treatment and prevention. Carbon 26-32 lamin A/C Homo sapiens 72-75 33309822-5 2021 The use of C-H5 design at a 2 m/s wind speed increases the decrement lag of burnt brick, mud brick, laterite stone, and cinder concrete composite wall envelopes by 48.1%, 49.0%, 59.5%, and 47.0%, respectively, relative to the common wall design (C-H1) in non-air-conditioned buildings. Carbon 11-12 SUN domain containing ossification factor Homo sapiens 246-250 33048295-3 2021 The absorption enhancement (EMAC) of the black carbon was calculated using a two-step solvent dissolution protocol and found 1.96 +- 0.68, 1.64 +- 0.38, and 2.40 +- 0.76 for Qingdao summer (QS), Qingdao autumn (QA), and SYS, respectively. Carbon 47-53 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 220-223 14527463-5 2003 Some of the synthesized carbons provide higher eta values than those for such commercial adsorbents as Hypercarb and Envicarb. Carbon 24-31 endothelin receptor type A Homo sapiens 47-50 33048295-5 2021 These sources increased the absorption of black carbon by a factor of 1.25 +- 0.11 (secondary aerosol), 1.21 +- 0.20 (industrial emissions), 1.17 +- 0.08 (coal combustion), 1.09 +- 0.07 (vehicle emissions), 1.08 +- 0.17 (sea salt), and 1.04 +- 0.10 (soil dust). Carbon 48-54 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 221-224 32949301-5 2021 Cells were basally stimulated with agonists Pam2CSK4 (Pam; TLR2), polyinosinic/polycytidylic acid (Poly I:C; TLR3), and lipopolysaccharide (LPS; TLR4) for 24 h. Supernatants were evaluated with ELISA for cytokines TNFalpha, IL-6, and IL-1beta. Carbon 0-1 toll like receptor 4 Homo sapiens 145-149 14558143-6 2003 Northern blot analyses showed that, as in S. cerevisiae, the steady-state ICL1 mRNA levels depend on the carbon source used for cell growth. Carbon 105-111 isocitrate lyase 1 Saccharomyces cerevisiae S288C 74-78 32949301-5 2021 Cells were basally stimulated with agonists Pam2CSK4 (Pam; TLR2), polyinosinic/polycytidylic acid (Poly I:C; TLR3), and lipopolysaccharide (LPS; TLR4) for 24 h. Supernatants were evaluated with ELISA for cytokines TNFalpha, IL-6, and IL-1beta. Carbon 0-1 interleukin 1 alpha Homo sapiens 234-242 33513971-1 2021 To improve the oxidative stability of biodiesel fuel (BDF), the polyunsaturated fatty acid methyl esters (poly-FAME) presented in commercial palm oil-derived biodiesel fuel (palm-BDF) were selectively hydrogenated to monounsaturated fatty acid methyl esters (mono-FAME) under a mild condition (80 C, 0.5 MPa) using activated carbon (AC)-supported Pd catalysts with a Pd loading of 1 wt.%. Carbon 326-332 benign adult familial myoclonic epilepsy 1 Homo sapiens 111-115 33513971-1 2021 To improve the oxidative stability of biodiesel fuel (BDF), the polyunsaturated fatty acid methyl esters (poly-FAME) presented in commercial palm oil-derived biodiesel fuel (palm-BDF) were selectively hydrogenated to monounsaturated fatty acid methyl esters (mono-FAME) under a mild condition (80 C, 0.5 MPa) using activated carbon (AC)-supported Pd catalysts with a Pd loading of 1 wt.%. Carbon 334-336 benign adult familial myoclonic epilepsy 1 Homo sapiens 111-115 33513971-4 2021 The 1%Pd/AC (nit) catalyst, prepared using Pd(NO3)2, presented high performance for selective hydrogenation of poly-FAME into mono-FAME with high oxidation stability, owning to its large Pd particles (8.4 nm). Carbon 9-11 benign adult familial myoclonic epilepsy 1 Homo sapiens 116-120 33513971-4 2021 The 1%Pd/AC (nit) catalyst, prepared using Pd(NO3)2, presented high performance for selective hydrogenation of poly-FAME into mono-FAME with high oxidation stability, owning to its large Pd particles (8.4 nm). Carbon 9-11 benign adult familial myoclonic epilepsy 1 Homo sapiens 131-135 33210665-2 2021 In this paper, a novel flexible, disposable sensor for Cd2+ and Pb2+ with ultrahigh sensitivity and a fast response, based on acid-etched Fe/Fe2O3 encapsulated into a disposable carbon cloth electrode, has been successfully fabricated. Carbon 178-184 CD2 molecule Homo sapiens 55-58 33367431-5 2021 Here, we report the preparation, characterisation and in vivo evaluation of tetrazine-functionalised boron-rich carbon dots, which show very fast clearance and low tumour uptake after intravenous administration in a mouse HER2 (human epidermal growth factor receptor 2)-positive tumour model. Carbon 112-118 erb-b2 receptor tyrosine kinase 2 Mus musculus 222-226 33401736-0 2021 Environmental Impacts of Glass- and Carbon-Fiber-Reinforced Polymer Bar-Reinforced Seawater and Sea Sand Concrete Beams Used in Marine Environments: An LCA Case Study. Carbon 36-42 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 83-86 33401736-1 2021 Application of glass- or carbon-fiber-reinforced polymer (GFRP/CFRP) bars makes the direct use of seawater and sea sand concrete (SWSSC) in construction feasible, which is of high interest in order to conserve the limited resources of fresh water and river sand. Carbon 25-31 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 98-101 33531997-8 2021 Moreover, carbon ion induced a robust (up to 28 folds) p-MLKL in the PR-NPC cells as well as sensitive cells (up to 6-fold) coupled with a lower level of BCL-x expression and increased GM-CSF implicated in resculputure of immune system. Carbon 10-16 colony stimulating factor 2 Homo sapiens 185-191 33373103-4 2021 Herein, a highly stable hosted Li with an LiF dominated SEI has successfully been achieved through metal-free fluorinated carbon fibers (FCF) with strong lithiophilicity. Carbon 122-128 LIF interleukin 6 family cytokine Homo sapiens 42-45 33374659-4 2020 The sample of LFP/C-xZnO (x = 3 wt%) exhibited well-dispersed spherical particles and remarkable cycling stability (initial discharge capacities of 138.7 mAh/g at 0.1 C, maintained 94.8% of the initial capacity after 50 cycles at 0.1 C). Carbon 18-19 lamin A/C Homo sapiens 14-17 33374865-1 2020 Phosphoenolpyruvate carboxylase (PEPC) is an enzyme with key roles in carbon and nitrogen metabolisms. Carbon 70-76 phosphoenolpyruvate carboxylase Nicotiana tabacum 0-31 33374865-1 2020 Phosphoenolpyruvate carboxylase (PEPC) is an enzyme with key roles in carbon and nitrogen metabolisms. Carbon 70-76 phosphoenolpyruvate carboxylase Nicotiana tabacum 33-37 32783994-1 2020 Phosphoenolpyruvate carboxylase (PEPC) is a carbon fixation enzyme which probably plays crucial roles in seed development. Carbon 44-50 phosphoenolpyruvate carboxylase, housekeeping isozyme Glycine max 0-31 32783994-1 2020 Phosphoenolpyruvate carboxylase (PEPC) is a carbon fixation enzyme which probably plays crucial roles in seed development. Carbon 44-50 phosphoenolpyruvate carboxylase, housekeeping isozyme Glycine max 33-37 33335640-2 2020 The electrochemical reduction of CO2 (CO2RR) is one of the possible conversion processes that can be employed to close the artificial carbon cycle, mimicking nature"s photosynthesis. Carbon 134-140 complement C2 Homo sapiens 38-43 32919661-7 2020 Then, the suspension of the TiO2@CuO-N-rGO nano-composite was drop casted on the surface of the glassy carbon electrode (GCE/TiO2@CuO-N-rGO). Carbon 103-109 aminomethyltransferase Homo sapiens 121-124 33393270-0 2020 [Effects of ant disturbance on soil organic carbon cycle: A review.] Carbon 44-50 solute carrier family 25 member 6 Homo sapiens 12-15 33393270-3 2020 We summarized the effects of ant disturbance on soil organic carbon cycle. Carbon 61-67 solute carrier family 25 member 6 Homo sapiens 29-32 33393270-5 2020 By re-shaping soil microbial community structure, regulating the succession process and pattern of vegetation, ant nesting directly or indirectly affects the source, allocation, stability, and microcosmic molecular characteristics of soil organic carbon, scaling from micro, local, to landscape scale. Carbon 247-253 solute carrier family 25 member 6 Homo sapiens 111-114 33393270-6 2020 In the future, more attentions should be paid on quantifying the contribution of ant disturbance combined with the fluctuations in environmental factors to soil carbon flux dynamics, establishing quantitative model to link and unify ant-induced soil carbon cycle process, and clari-fying mechanisms underlying the impacts of ants on the stability of soil organic carbon pool, and finally revealing the "ecological engineers" role of ants in regulating soil organic carbon cycling. Carbon 161-167 solute carrier family 25 member 6 Homo sapiens 51-54 31981690-2 2020 This human intersex condition is linked to a mutation in the steroid-5alpha-reductase type 2 (SRD5alpha2) gene, which usually produces an important enzyme capable of reducing the Delta4-ene of steroid C-19 and C-21 into a 5alpha-stereoisomer. Carbon 201-202 steroid 5 alpha-reductase 2 Homo sapiens 94-104 31981690-2 2020 This human intersex condition is linked to a mutation in the steroid-5alpha-reductase type 2 (SRD5alpha2) gene, which usually produces an important enzyme capable of reducing the Delta4-ene of steroid C-19 and C-21 into a 5alpha-stereoisomer. Carbon 201-202 delta like canonical Notch ligand 4 Homo sapiens 179-185 32242652-2 2020 Herein, a general strategy combining sol-gel and carbonization-assisted route was proposed to facilely fabricate a series of TMPs nanoparticles including CoP, MoP, FeP, Cu2P, Ni2P, PtP2, FeNiP, CoNiP and FeCoNiP, coupled in amorphous carbon matrix with one-step carbon composite formation. Carbon 49-55 caspase recruitment domain family member 16 Homo sapiens 154-157 33867541-7 2020 Most stardust is thought to originate in three distinct processes in carbon- and/or oxygen-rich mineral-forming stars: (1) condensation in the cooling, expanding atmospheres of asymptotic giant branch stars; (2) during the catastrophic explosions of supernovae, most commonly core collapse (Type II) supernovae; and (3) classical novae explosions, the consequence of runaway fusion reactions at the surface of a binary white dwarf star. Carbon 69-75 protein associated with LIN7 1, MAGUK p55 family member Homo sapiens 5-13 32341997-5 2020 First, through the enrichment of deuterated glutamine in the polyQ sequence of mutant Huntingtin (mHtt) exon1 proteins for Huntington"s disease, we achieved sensitive and specific stimulated Raman scattering (SRS) imaging of carbon-deuterium bonds (C-D) from aggregates without GFP labeling, which is commonly employed in fluorescence microscopy. Carbon 225-231 huntingtin Mus musculus 98-102 32203650-1 2020 Metal-nitrogen-carbon (MNC) nanocomposites have been hailed as promising, efficient electrocatalysts toward oxygen reduction reaction (ORR) due to the formation of MNx coordination moieties. Carbon 15-21 keratin 86 Homo sapiens 164-167 32212683-4 2020 Furthermore, we confirm the formation of the Au-C bond by measuring an analogous series of molecules prepared ex situ with the complex AuI(PPh3) in place of the iodide. Carbon 48-49 protein phosphatase 4 catalytic subunit Homo sapiens 139-143 32202754-3 2020 As a proof of concept, heterostructured Au/CoP nanoparticles dispersed on nitrogen-doped carbon with unique porosity, denoted as Au/CoP@NC-3, are synthesized by thermal treatment of Au nanoparticle-incorporated ZIF-67 precursor. Carbon 89-95 caspase recruitment domain family member 16 Homo sapiens 43-46 31846340-3 2020 With the use of a graphitic carbon-capped tungsten nanoelectrode as a noncontact "milling" tool in a transmission electron microscope, graphene edge atoms approached by the tool tip are locally evaporated, thus allowing a freestanding graphene sheet to be tailored with high precision and flexibility. Carbon 18-34 TOR signaling pathway regulator Homo sapiens 178-181 31982717-0 2020 Surface modification of coordination polymers to enable the construction of CoP/N,P-codoped carbon nanowires towards high-performance lithium storage. Carbon 92-98 caspase recruitment domain family member 16 Homo sapiens 76-79 31982717-1 2020 A one-dimensional hybrid with N,P co-doped carbon nanowires threaded CoP nanoparticles is rationally fabricated by employing surface modified coordination polymers as a precursor. Carbon 43-49 caspase recruitment domain family member 16 Homo sapiens 69-72 31982717-2 2020 Ultrasmall CoP nanoparticlesare well encapsulated in N,P co-doped carbon nanowires, which can effectively buffer the volume expansion of active CoP and facilitate fast lithium-ion/electron transfer during charge/discharge processes. Carbon 66-72 caspase recruitment domain family member 16 Homo sapiens 11-14 31982717-2 2020 Ultrasmall CoP nanoparticlesare well encapsulated in N,P co-doped carbon nanowires, which can effectively buffer the volume expansion of active CoP and facilitate fast lithium-ion/electron transfer during charge/discharge processes. Carbon 66-72 caspase recruitment domain family member 16 Homo sapiens 144-147 31967407-6 2020 In particular two proteins, the cellular mRNA deadenylase CCR4 (carbon catabolite repressor 4)-NOT (Negative on TATA) complex subunit 2/9 (CNOT2/9) and the serine hydroxymethyltransferase that catalyzes the reversible interconversions of serine and glycine (SHMT1) were found at dramatic low levels in the thymic epithelia of more malignant subtype, thymic squamous cell carcinoma (TSCC). Carbon 64-70 serine hydroxymethyltransferase 1 Homo sapiens 258-263 31988081-6 2020 Here we present NMR studies demonstrating gp74 contains an alpha-helical insertion in the Omega-loop, which connects the two beta-strands of the betabetaalpha fold, and a disordered C-terminal tail. Carbon 182-183 Gp74 Escherichia phage HK97 42-46 31988081-8 2020 Further, the Omega-loop insert and C-terminal tail contribute to gp74-mediated DNA digestion and to gp74 activity in phage morphogenesis. Carbon 35-36 Gp74 Escherichia phage HK97 65-69 31988081-8 2020 Further, the Omega-loop insert and C-terminal tail contribute to gp74-mediated DNA digestion and to gp74 activity in phage morphogenesis. Carbon 35-36 Gp74 Escherichia phage HK97 100-104 31988081-9 2020 The data presented here enrich our molecular-level understanding of how HNH endonucleases enhance terminase-mediated digestion of the cos site and contribute to the phage replication cycle.Importance This study demonstrates that residues outside the canonical betabetaalpha fold, namely the Omega-loop alpha-helical insert and a disordered C-terminal tail, control the activity of the HNH endonuclease gp74. Carbon 340-341 Gp74 Escherichia phage HK97 402-406 31770723-0 2020 Ce-doped CoP nanoparticles embedded in carbon nanotubes as an efficient and durable catalyst for hydrogen evolution. Carbon 39-45 caspase recruitment domain family member 16 Homo sapiens 9-12 31770723-1 2020 In this work, a cerium doped CoP nanoparticles (NPs) embedded in carbon nanotubes (CNTs) for efficient and durable hydrogen evolution was developed. Carbon 65-71 caspase recruitment domain family member 16 Homo sapiens 29-32 31778989-1 2020 In this work, silver nanoparticles (Ag NPs) were decorated into the cavities of ZIF-8 to fabricate a novel Ag NPs/ZIF-8 modified glassy carbon electrode (GCE) for electrochemical sensing of chloride ion. Carbon 136-142 aminomethyltransferase Homo sapiens 154-157 32256508-2 2020 Here, we present data consistent with the positive effect that the expression of the Arabidopsis thaliana H+-PPase (AVP1) has on reduced carbon partitioning and yield increases in wheat. Carbon 137-143 Inorganic H pyrophosphatase family protein Arabidopsis thaliana 116-120 32256508-6 2020 Interestingly, 14C-labeling experiments provided evidence for enhanced carbon partitioning between shoots and roots, and between flag leaves and milk stage kernels in AVP1 expressing Bobwhite lines. Carbon 71-77 Inorganic H pyrophosphatase family protein Arabidopsis thaliana 167-171 32182256-4 2020 Based on this analysis, OVCA2 was confirmed as a serine hydrolase with a strong preference for long-chain alkyl ester substrates (>10-carbons) and high selectivity against a variety of short, branched, and substituted esters. Carbon 134-141 OVCA2 serine hydrolase domain containing Homo sapiens 24-29 31945433-1 2020 We report here on the green synthesis method of hydrogel nanocomposite (Na-Ala/Chit-cl-polyAAm/CQDs) incorporated with carbon quantum dots for picric acid sensing and biebrich scharlet dye removal from industrial waste water. Carbon 119-125 chitinase 1 Homo sapiens 79-83 31967346-4 2020 Interaction of a conserved concave surface of its core domain with the Galpha C-terminus appears to mediate formation of the initial Ric-8A/GalphaGDP intermediate, followed by the formation of a stable nucleotide-free complex. Carbon 78-79 succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens 71-77 31967346-6 2020 The distal portion of the C-terminal tail of Ric-8A forms a smaller secondary interface, which ostensibly binds the switch II region of Galpha, facilitating binding of GTP. Carbon 26-27 succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens 136-142 32098795-0 2020 BET 1: The clinical impact of policies aimed at reducing the carbon footprint of emergency departments. Carbon 61-67 Bet1 golgi vesicular membrane trafficking protein Homo sapiens 0-5 31586916-4 2020 The resulting M-IANC-C nanostructure (melamine:PIA mass ratio of 1:2) depicted 228.18 wt.% and 82.08 wt.% adsorption capacity for benzene and toluene, respectively, which were 19.4 and 2.8 times higher than commercial activated carbon. Carbon 228-234 RPTOR independent companion of MTOR complex 2 Homo sapiens 47-50 31823472-2 2020 Whereas its anomeric carbon (C-1) is oxidized to a carboxy group, the hydroxy group on the C-2 carbon is replaced by hydrogen. Carbon 21-27 heterogeneous nuclear ribonucleoprotein C Homo sapiens 29-32 31922367-4 2020 The results presented here suggest that Gd3+ doping can lead to various concentration and temperature dependent effects on the polarization of [13 C6 ,2 H7 ]glucose, not necessarily similar to the effects observed in pyruvic acid or acetate in size or direction. Carbon 147-149 GRDX Homo sapiens 40-43 31922740-2 2020 Herein, a novel carbon-based CoP hybrid with spatial compartmentalization of CoP nanoparticles (NPs) in P-doped dual carbon shells is achieved via a cheap Co-glycerate-template strategy. Carbon 16-22 caspase recruitment domain family member 16 Homo sapiens 29-32 31922740-2 2020 Herein, a novel carbon-based CoP hybrid with spatial compartmentalization of CoP nanoparticles (NPs) in P-doped dual carbon shells is achieved via a cheap Co-glycerate-template strategy. Carbon 16-22 caspase recruitment domain family member 16 Homo sapiens 77-80 31922740-2 2020 Herein, a novel carbon-based CoP hybrid with spatial compartmentalization of CoP nanoparticles (NPs) in P-doped dual carbon shells is achieved via a cheap Co-glycerate-template strategy. Carbon 117-123 caspase recruitment domain family member 16 Homo sapiens 29-32 31922740-2 2020 Herein, a novel carbon-based CoP hybrid with spatial compartmentalization of CoP nanoparticles (NPs) in P-doped dual carbon shells is achieved via a cheap Co-glycerate-template strategy. Carbon 117-123 caspase recruitment domain family member 16 Homo sapiens 77-80 31922740-3 2020 Benefitted from the uniform atomic blending of Co2+ ions in the Co-glycerate precursors, CoP NPs in situ formed in the confined space with NaH2PO2 as phosphorus source during the annealing process; meanwhile, glycerate suffered carbonization and transformed into P-doped dual carbon shells during the annealing process, including interior thin carbon coating, closely encircled CoP NP, and peripheral hollow carbon sphere loading a lot of CoP NPs. Carbon 228-234 caspase recruitment domain family member 16 Homo sapiens 89-92 31922740-3 2020 Benefitted from the uniform atomic blending of Co2+ ions in the Co-glycerate precursors, CoP NPs in situ formed in the confined space with NaH2PO2 as phosphorus source during the annealing process; meanwhile, glycerate suffered carbonization and transformed into P-doped dual carbon shells during the annealing process, including interior thin carbon coating, closely encircled CoP NP, and peripheral hollow carbon sphere loading a lot of CoP NPs. Carbon 276-282 caspase recruitment domain family member 16 Homo sapiens 89-92 31922740-3 2020 Benefitted from the uniform atomic blending of Co2+ ions in the Co-glycerate precursors, CoP NPs in situ formed in the confined space with NaH2PO2 as phosphorus source during the annealing process; meanwhile, glycerate suffered carbonization and transformed into P-doped dual carbon shells during the annealing process, including interior thin carbon coating, closely encircled CoP NP, and peripheral hollow carbon sphere loading a lot of CoP NPs. Carbon 276-282 caspase recruitment domain family member 16 Homo sapiens 89-92 31870799-5 2020 Utilizing hits selected from a high throughput screening campaign, time-resolved X-ray crystallography, molecular dynamics, mass spectrometry, molecular modeling, protein mutagenesis and functional studies, we find that 2-naphtholmethylamino derivatives bound to this novel ectopic site of Schistosoma mansoni (Sm)TGR are transformed to covalent modifiers and react with its mobile selenocysteine-containing C-terminal arm. Carbon 408-409 thioredoxin reductase 3 Homo sapiens 314-317 31928655-7 2020 Combined experimental results using AtUev1B demonstrated that it is most likely farnesylated and that its C-terminal tail, particularly the catalytic Cys residue in the CaaX motif, plays critical roles in protein-protein interaction, nuclear exclusion and membrane association. Carbon 0-1 MMS ZWEI homologue 2 Arabidopsis thaliana 36-43 31715395-1 2020 To efficiently and selectively produce liquid hydrocarbon fuels, e.g., methanol, by CO2 photoelectrochemical reduction, CdS nanoparticles (NPs) anchored on the nitrogen-doped carbon particles (NCP) with core-shell dodecahedral porous structure were used as cathode catalysts. Carbon 51-57 CDP-diacylglycerol synthase 1 Homo sapiens 120-123 31715395-4 2020 CdS/NCP-500 catalyst exhibited a selectivity of 77.3% towards methanol with a total carbon atom conversion rate of 3052 nmol h-1 cm-2. Carbon 84-90 CDP-diacylglycerol synthase 1 Homo sapiens 0-3 31913017-0 2020 Recycling of FTO/TiO2 Substrates: Route toward Simultaneously High-Performance and Cost-Efficient Carbon-Based, All-Inorganic CsPbIBr2 Solar Cells. Carbon 98-104 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 13-16 31895395-0 2020 Metal-organic-framework-derived hierarchical Co/CoP-decorated nanoporous carbon polyhedra for robust high-energy storage hybrid supercapacitors. Carbon 73-79 caspase recruitment domain family member 16 Homo sapiens 48-51 31895395-2 2020 In this study, we successfully prepared cobalt phosphide and cobalt nanoparticles embedded into nitrogen-doped nanoporous carbon (CoP-CoNC/CC) using a simple precipitation method followed by pyrolysis-phosphatization. Carbon 122-128 caspase recruitment domain family member 16 Homo sapiens 130-133 31895395-7 2020 The higher performance can be attributed to the synergetic effect between CoP, Co metal, and the nitrogen-doped nanoporous carbon in three-dimensional carbon cloth (CC). Carbon 151-157 caspase recruitment domain family member 16 Homo sapiens 74-77 32154085-3 2020 This study reports that the Co-based coordination polymer (ZIF-67) anchoring on an indium-organic framework (InOF-1) composite (InOF-1@ZIF-67) is treated followed by carbonization and phosphorization to successfully obtain CoP nanoparticles-embedded carbon nanotubes and nitrogen-doped carbon materials (CoP-InNC@CNT). Carbon 166-172 caspase recruitment domain family member 16 Homo sapiens 223-226 32154085-3 2020 This study reports that the Co-based coordination polymer (ZIF-67) anchoring on an indium-organic framework (InOF-1) composite (InOF-1@ZIF-67) is treated followed by carbonization and phosphorization to successfully obtain CoP nanoparticles-embedded carbon nanotubes and nitrogen-doped carbon materials (CoP-InNC@CNT). Carbon 166-172 caspase recruitment domain family member 16 Homo sapiens 304-307 32154085-3 2020 This study reports that the Co-based coordination polymer (ZIF-67) anchoring on an indium-organic framework (InOF-1) composite (InOF-1@ZIF-67) is treated followed by carbonization and phosphorization to successfully obtain CoP nanoparticles-embedded carbon nanotubes and nitrogen-doped carbon materials (CoP-InNC@CNT). Carbon 250-256 caspase recruitment domain family member 16 Homo sapiens 223-226 31953408-5 2020 The stabilized Insig-2 downregulates lipogenesis through inhibiting the SREBP pathway, helping to channel the carbon flux to ATP generation and protecting myotubes from lipid over-accumulation. Carbon 110-116 insulin induced gene 2 Mus musculus 15-22 31761041-3 2020 Herein, gold-nanourchin conjugated anti-alpha-synuclein antibody was desired as the probe and seeded on single-walled carbon nanotube (SWCN) integrated interdigitated electrode (IDE). Carbon 118-124 synuclein alpha Homo sapiens 40-55 31998679-0 2019 One-Step Synthesis of N, P-Codoped Carbon Nanosheets Encapsulated CoP Particles for Highly Efficient Oxygen Evolution Reaction. Carbon 35-41 caspase recruitment domain family member 16 Homo sapiens 66-69 31998679-3 2019 In this work, we have constructed a new material, CoP nanoparticles, which are encapsulated by a biomolecule-derived N, P-codoped carbon nanosheets via a simple and facile one-step strategy. Carbon 130-136 caspase recruitment domain family member 16 Homo sapiens 50-53 31998679-6 2019 Moreover, the coverage of N, P-doped carbon can prevent the CoP nanoparticles from corrosion under the harsh reaction medium to achieve high and stable activity. Carbon 37-43 caspase recruitment domain family member 16 Homo sapiens 60-63 31841300-2 2020 Herein, we report a unique bimetallic diphosphide pair (FeP2-NiP2) forming spherical nanocages encapsulated in P-doped carbon layers (FeP2-NiP2@PC) as advanced bifunctional electrocatalyst synthesized by a very facile phosphorization approach. Carbon 119-125 BCL2 interacting protein 2 Homo sapiens 61-65 31841300-2 2020 Herein, we report a unique bimetallic diphosphide pair (FeP2-NiP2) forming spherical nanocages encapsulated in P-doped carbon layers (FeP2-NiP2@PC) as advanced bifunctional electrocatalyst synthesized by a very facile phosphorization approach. Carbon 119-125 BCL2 interacting protein 2 Homo sapiens 139-143 31738360-8 2020 When compared with direct fluorination using elemental fluorine, deoxofluorination using SF4 has the advantages of high reactivity with hydroxy groups and the preservation of the carbon skeleton, and the reaction results in the formation of graphite oxyfluoride. Carbon 179-185 SURP and G-patch domain containing 1 Homo sapiens 89-92 32717463-8 2020 Discriminant analysis of data from 533 published datasets revealed that biochar derived from hardwood (HBC) and softwood generally have greater surface area and carbon content, but lower content of oxygen and mineral constituents, than manure- (MBC) and grass-derived biochars (GBC). Carbon 161-167 keratin 88, pseudogene Homo sapiens 103-106 32986402-7 2020 All the anisotropic OSC molecules grown on poly(3,4-ethylenedioxythiophene)-polystyrene sulfonate (PEDOT:PSS) electrodes show a greater degree of molecular ordering than those grown on Au and multiwalled carbon nanotube/PEDOT:PSS electrodes. Carbon 204-210 lanosterol synthase Homo sapiens 20-23 33097666-8 2020 These findings demonstrate compartmentalization of Ca2+ signals dictates the odorant receptor OR2W3-induced ASM relaxation and identify a previously unrecognized E-C coupling mechanism that could be exploited in the development of therapeutics to treat obstructive lung diseases. Carbon 51-52 H19 imprinted maternally expressed transcript Homo sapiens 108-111 33156884-0 2020 Prostate-specific antigen dynamics after neoadjuvant androgen-deprivation therapy and carbon ion radiotherapy for prostate cancer. Carbon 86-92 kallikrein related peptidase 3 Homo sapiens 0-25 33156884-1 2020 BACKGROUND: This study aimed to explain the dynamics of prostate-specific antigen (PSA) levels in patients with prostate cancer who were treated with carbon ion radiotherapy (CIRT) and neoadjuvant androgen-deprivation therapy (ADT). Carbon 150-156 kallikrein related peptidase 3 Homo sapiens 56-81 33156884-1 2020 BACKGROUND: This study aimed to explain the dynamics of prostate-specific antigen (PSA) levels in patients with prostate cancer who were treated with carbon ion radiotherapy (CIRT) and neoadjuvant androgen-deprivation therapy (ADT). Carbon 150-156 kallikrein related peptidase 3 Homo sapiens 83-86 14517308-7 2003 Thus, TOR may sense optimal nitrogen- and carbon-limiting conditions to modulate Ime1 function. Carbon 42-48 transcription factor IME1 Saccharomyces cerevisiae S288C 81-85 33150458-0 2020 Mutual influence of tetrel and halogen bonds between XCN (X=Cl, Br) and 4-TF3-pyridine (T=C, Si, Ge). Carbon 54-55 chromosome 12 open reading frame 73 Homo sapiens 64-66 32889745-2 2020 The lone pair on the N atom of HCN is a better electron donor in the aerogen bond than the pi electron on the C=C bond of C 2 H 4 . Carbon 110-111 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 31-34 12855692-2 2003 Rat short/branched chain acyl-CoA dehydrogenases (SBCAD) are more active toward substrates with longer carbon side chains than human SBCAD, whereas the human enzyme utilizes substrates with longer primary carbon chains. Carbon 103-109 acyl-CoA dehydrogenase short/branched chain Homo sapiens 4-48 12855692-2 2003 Rat short/branched chain acyl-CoA dehydrogenases (SBCAD) are more active toward substrates with longer carbon side chains than human SBCAD, whereas the human enzyme utilizes substrates with longer primary carbon chains. Carbon 103-109 acyl-CoA dehydrogenase, short/branched chain Rattus norvegicus 50-55 32886808-5 2020 Replacement of the Pd/C catalyst with one prepared in-situ by reduction of palladium trifluoroacetate with deuterium gas and dispersed upon micronised polytetrafluoroethylene, led to much reduced scrambling (typically 0-6% compared with up to 40% for palladium on carbon) and to high atom% abundance, regiospecific labelling. Carbon 264-270 gastrin Homo sapiens 117-120 12855692-2 2003 Rat short/branched chain acyl-CoA dehydrogenases (SBCAD) are more active toward substrates with longer carbon side chains than human SBCAD, whereas the human enzyme utilizes substrates with longer primary carbon chains. Carbon 205-211 acyl-CoA dehydrogenase short/branched chain Homo sapiens 4-48 32900978-0 2020 Triple-localized WHIRLY2 influences leaf senescence and silique development via carbon allocation. Carbon 80-86 WHIRLY 2 Arabidopsis thaliana 17-24 12855692-2 2003 Rat short/branched chain acyl-CoA dehydrogenases (SBCAD) are more active toward substrates with longer carbon side chains than human SBCAD, whereas the human enzyme utilizes substrates with longer primary carbon chains. Carbon 205-211 acyl-CoA dehydrogenase, short/branched chain Rattus norvegicus 50-55 32900978-8 2020 Our results suggest that WHY2 in plastids, mitochondria, and the nucleus plays a vital role in alteration of carbon reallocation from maternal tissue to filial tissue. Carbon 109-115 WHIRLY 2 Arabidopsis thaliana 25-29 12855692-5 2003 Molecular modeling of the SBCAD structure suggests that position 104 at the bottom of the substrate binding pocket is important in determining the length of the primary carbon chain that can be accommodated. Carbon 169-175 acyl-CoA dehydrogenase short/branched chain Homo sapiens 26-31 12855707-3 2003 ApoCII prevented the inhibition by bis-ANS, and was also able to restore the activity of inhibited LPL in a competitive manner, but only with triacylglycerols with acyl chains longer than three carbons. Carbon 194-201 apolipoprotein C2 Homo sapiens 0-6 12736159-4 2003 Studies investigating the effects of the chain length of saturated fatty acids [from butyric (C4) to stearic (C18) acids] revealed that only fatty acids with a chain length superior or equal to eight carbons effectively inhibited insulin-stimulated leptin secretion. Carbon 200-207 leptin Rattus norvegicus 249-255 33070855-0 2020 Pyridine-2-sulfonic (or carboxylic) acid modified glassy carbon electrode for anodic stripping voltammetry analysis of Cd2+ and Pb2. Carbon 57-63 CD2 molecule Homo sapiens 119-122 31621838-6 2020 Primary outcome was change in bone resorption marker C-terminal telopeptide of collagen (CTx). Carbon 53-54 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 89-92 12885865-1 2003 Sucrose-phosphate synthase (SPS) is one of the key regulatory enzymes in carbon assimilation and partitioning in plants. Carbon 73-79 sucrose-phosphate synthase Zea mays 28-31 33195109-2 2020 In this work, V-doped CoP nanosheet arrays supported on the carbon cloth (V-CoP/CC) are fabricated though a facile water-bath/phosphorization method. Carbon 60-66 caspase recruitment domain family member 16 Homo sapiens 22-25 33195109-2 2020 In this work, V-doped CoP nanosheet arrays supported on the carbon cloth (V-CoP/CC) are fabricated though a facile water-bath/phosphorization method. Carbon 60-66 caspase recruitment domain family member 16 Homo sapiens 76-79 12953122-12 2003 However, the stimulation of AtNrt2.1 transcript accumulation by sucrose and glucose is abolished in an antisense AtHXK1 line, suggesting that HXK catalytic activity and carbon metabolism downstream of the HXK step are crucial for the sugar regulation of AtNrt2.1 expression. Carbon 169-175 hexokinase Arabidopsis thaliana 115-118 33113947-3 2020 Strongly deshielded C-O-O-H 1H-NMR resonances of diastereomeric endo-hydroperoxides in the region of 8.8 to 9.6 ppm were shown to be due to intramolecular hydrogen bonding interactions of the hydroperoxide proton with an oxygen atom of the five-member endo-peroxide ring. Carbon 20-21 mannosidase endo-alpha Homo sapiens 64-68 33113947-3 2020 Strongly deshielded C-O-O-H 1H-NMR resonances of diastereomeric endo-hydroperoxides in the region of 8.8 to 9.6 ppm were shown to be due to intramolecular hydrogen bonding interactions of the hydroperoxide proton with an oxygen atom of the five-member endo-peroxide ring. Carbon 20-21 mannosidase endo-alpha Homo sapiens 252-256 12915666-1 2003 Cytochrome P450c17 catalyzes both 17alpha-hydroxylation and 17,20-lyase conversion of 21-carbon steroids to 19-carbon precursors of sex steroids. Carbon 89-95 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 0-18 33043956-0 2020 Synthesis of alpha-aminooxy amides through [3 + 3] cycloaddition and Sc(OTf)3-catalyzed double C-N bond cleavage in a one-pot reaction. Carbon 95-96 POU class 5 homeobox 1 Homo sapiens 69-77 33043956-3 2020 Mechanistic studies show that the reaction initially proceeds through [3 + 3] cycloaddition between N-vinyl nitrones and aza-oxyallyl cations generated from alpha-bromohydroxamates to afford six-membered N,O-heterocycles, followed by double C-N bond cleavage in the presence of the Sc(OTf)3 catalyst. Carbon 241-242 POU class 5 homeobox 1 Homo sapiens 282-290 12710887-8 2003 The detection of TeTx- and H(C)-TeTx-induced phosphorylation at Ser(9) of glycogen synthase kinase 3beta confirms Akt activation. Carbon 29-30 glycogen synthase kinase 3 beta Rattus norvegicus 74-104 32996938-5 2020 The interaction between CH3OH and CCl4 at the molecular level can be twofold: hydrogen bond (O-HCl) and halogen bond (C-ClO) interaction. Carbon 24-25 C-C motif chemokine ligand 4 Homo sapiens 34-38 33000831-6 2020 Owing to the triple functional role of carbon dots underlayer in improving the interfacial properties of FTO/hematite and providing carbon source for the overlayer as well as the change in the iron oxidation state, the bulk and interfacial charge transfer dynamics of hematite are significantly enhanced, and consequently led to a remarkable enhancement in the photocurrent density. Carbon 39-45 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 105-108 12853640-6 2003 Such yeast with a mutated allele of RRF1, rrf1-L209P, grew on a non-fermentable carbon source at 30 but not at 36 degrees C, where mitochondrial but not total protein synthesis was 90% inhibited. Carbon 80-86 Rrf1p Saccharomyces cerevisiae S288C 36-40 33057182-0 2020 Author Correction: Synergy between the anthocyanin and RDR6/SGS3/DCL4 siRNA pathways expose hidden features of Arabidopsis carbon metabolism. Carbon 123-129 RNA-dependent RNA polymerase 6 Arabidopsis thaliana 55-59 33057182-0 2020 Author Correction: Synergy between the anthocyanin and RDR6/SGS3/DCL4 siRNA pathways expose hidden features of Arabidopsis carbon metabolism. Carbon 123-129 XS domain-containing protein / XS zinc finger domain-containing protein-like protein Arabidopsis thaliana 60-64 12853640-6 2003 Such yeast with a mutated allele of RRF1, rrf1-L209P, grew on a non-fermentable carbon source at 30 but not at 36 degrees C, where mitochondrial but not total protein synthesis was 90% inhibited. Carbon 80-86 Rrf1p Saccharomyces cerevisiae S288C 42-46 12853652-7 2003 Herein, the bait was fused to the (beta)c chain and its modifying enzyme to the GM-CSFRalpha chain (or vice versa). Carbon 40-41 colony stimulating factor 2 receptor subunit alpha Homo sapiens 80-92 32914956-6 2020 We achieve a Tf of -0.6 C using carbon nanotubes based electrodes with an E of 3 x 107 V/m. Carbon 32-38 coagulation factor III, tissue factor Homo sapiens 13-15 12855052-4 2003 An overproduction of cAMP by beta(1)-adrenergic receptor stimulation, resulting in overphosphorylation of troponin I, may reduce calcium binding by troponin C. Carbon 157-158 beta-1 adrenergic receptor Ovis aries 29-56 12945913-2 2003 Although this series corresponds to a large modulation in the electrophilic properties of the six-membered ring, all reactions first lead to the quantitative formation of the sigma-adducts C-3a-i, C-5 and C-6 arising from covalent addition of the nucleophile to the C-7 carbon. Carbon 270-276 complement C6 Homo sapiens 205-208 33028818-4 2020 A series of C-X (X = S, Se, Te, H, P) and C-C bonds are efficiently constructed under simple and mild reaction conditions. Carbon 12-13 squalene epoxidase Homo sapiens 24-26 33028818-4 2020 A series of C-X (X = S, Se, Te, H, P) and C-C bonds are efficiently constructed under simple and mild reaction conditions. Carbon 42-43 squalene epoxidase Homo sapiens 24-26 12822789-5 2003 When frequency dependence of attenuation was expressed as alpha = alpha(0)f(beta), the results were as follows: alpha0 = 1.07 x 10(-16) s2/m and beta = 2 for C-7980 and alpha0 = 5.16 x 10(-9) s(1.25)/m and beta = 1.25 for C-7740. Carbon 158-159 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 145-153 33020580-1 2020 Glutamate dehydrogenase (GDH) is a key enzyme interlinking carbon and nitrogen metabolism. Carbon 59-65 glutamate dehydrogenase 1 Homo sapiens 0-23 33020580-1 2020 Glutamate dehydrogenase (GDH) is a key enzyme interlinking carbon and nitrogen metabolism. Carbon 59-65 glutamate dehydrogenase 1 Homo sapiens 25-28 31685550-0 2020 Function of the MYND domain and C-terminal region in regulating the subcellular localization and catalytic activity of the SMYD family lysine methyltransferase Set5. Carbon 32-33 S-adenosylmethionine-dependent methyltransferase Saccharomyces cerevisiae S288C 160-164 16256594-3 2003 The specific surface areas (S(BET)) of the activated carbons prepared by single-step activation (direct activation without oxidation and carbonization) were higher than those resulting from two-step activation (oxidation-activation and carbonization-activation) and three-step activation (oxidation-carbonization-activation) methods. Carbon 53-60 delta/notch like EGF repeat containing Homo sapiens 30-33 31908776-2 2020 We have previously shown that central carbon metabolism is rewired in pancreatic ductal adenocarcinoma (PDA) to support proliferation through a glutamate oxaloacetate transaminase 1 (GOT1)-dependent pathway. Carbon 38-44 glutamic-oxaloacetic transaminase 1 Homo sapiens 144-181 32980099-4 2020 The surface treatment of the carbon black/PLA electrodes fabricated by both 3D pen and FDM 3D-printing procedures provided substantial improvement of the electrochemical activity by removing excess of PLA, which was confirmed by scanning electron microscopic images for electrodes fabricated by both procedures. Carbon 29-35 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 79-82 32980111-0 2020 A self-enhanced ECL-RET immunosensor for the detection of CA19-9 antigen based on Ru(bpy)2(phen-NH2)2+ - Amine-rich nitrogen-doped carbon nanodots as probe and graphene oxide grafted hyperbranched aromatic polyamide as platform. Carbon 131-137 ret proto-oncogene Homo sapiens 20-23 31908776-2 2020 We have previously shown that central carbon metabolism is rewired in pancreatic ductal adenocarcinoma (PDA) to support proliferation through a glutamate oxaloacetate transaminase 1 (GOT1)-dependent pathway. Carbon 38-44 glutamic-oxaloacetic transaminase 1 Homo sapiens 183-187 18969042-1 2003 A renewable three-dimensional chemically modified carbon ceramic electrode containing Ru [(tpy)(bpy)Cl] PF(6) was constructed by sol-gel technique. Carbon 50-56 sperm associated antigen 17 Homo sapiens 104-109 32502756-0 2020 RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells. Carbon 42-48 ring finger protein 8 Homo sapiens 0-4 33022992-7 2020 Hexokinase 2 is the key enzyme involved in central carbon metabolism and is also treated as a calorie restriction mimetic. Carbon 51-57 hexokinase 2 Saccharomyces cerevisiae S288C 0-12 12547836-7 2003 Alignment of the protein structures of the ligand-binding domains of ERalpha and ERbeta revealed one mismatched residue, Leu-384 in ERalpha and Met-283 in ERbeta, which may be responsible for making contact with the methyl substituent at the chiral carbon of IA-S and IA-R. Mutagenesis and exchange of this one residue showed that the binding of IA-R and IA-S was not affected by this mutation in ERalpha and ERbeta. Carbon 249-255 estrogen receptor 2 Homo sapiens 81-87 32502756-4 2020 Interestingly, ATM inhibition caused a substantial DSB repair defect after high-LET carbon-ion irradiation. Carbon 84-90 ATM serine/threonine kinase Homo sapiens 15-18 32502756-11 2020 Finally, we showed that RNF8 depletion augmented radiosensitivity after high-LET carbon-ion irradiation. Carbon 81-87 ring finger protein 8 Homo sapiens 24-28 12547836-7 2003 Alignment of the protein structures of the ligand-binding domains of ERalpha and ERbeta revealed one mismatched residue, Leu-384 in ERalpha and Met-283 in ERbeta, which may be responsible for making contact with the methyl substituent at the chiral carbon of IA-S and IA-R. Mutagenesis and exchange of this one residue showed that the binding of IA-R and IA-S was not affected by this mutation in ERalpha and ERbeta. Carbon 249-255 estrogen receptor 2 Homo sapiens 155-161 32502756-12 2020 This study suggests that the inhibition of RNF8 activity or its downstream pathway may augment the efficacy of high-LET carbon-ion therapy. Carbon 120-126 ring finger protein 8 Homo sapiens 43-47 32222383-7 2020 This study expands our knowledge of methanogenesis at high temperatures and the involvement of these microorganisms in the carbon and nitrogen cycles of deep-sea hydrothermal environments. Carbon 123-129 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 158-161 12547836-7 2003 Alignment of the protein structures of the ligand-binding domains of ERalpha and ERbeta revealed one mismatched residue, Leu-384 in ERalpha and Met-283 in ERbeta, which may be responsible for making contact with the methyl substituent at the chiral carbon of IA-S and IA-R. Mutagenesis and exchange of this one residue showed that the binding of IA-R and IA-S was not affected by this mutation in ERalpha and ERbeta. Carbon 249-255 estrogen receptor 2 Homo sapiens 155-161 12675908-6 2003 Analysis of cytochrome c in cytosolic and mitochondria-enriched subcellular fractions revealed that induction of SM-20 led to the accumulation of cytochrome c in the cytosol. Carbon 12-13 egl-9 family hypoxia-inducible factor 3 Rattus norvegicus 113-118 32970058-0 2020 Tri-(Fe/F/N)-doped porous carbons as electrocatalysts for the oxygen reduction reaction in both alkaline and acidic media. Carbon 26-33 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 0-3 31747679-1 2020 The electrocatalytic carbon dioxide (CO2) reduction reaction (CO2RR) to value-added fuels and feedstocks provides a sustainable and carbon-neutral approach to the storage of intermittent renewable electricity1. Carbon 21-27 complement C2 Homo sapiens 37-40 31775157-7 2020 SPT16 binds nucleosomal DNA and tethers H2A-H2B through its C-terminal domain by acting as a placeholder for DNA. Carbon 60-61 SPT16 homolog, facilitates chromatin remodeling subunit Homo sapiens 0-5 12744456-1 2003 Phosphoenolpyruvate carboxylases (PEPCs), one form of which in each legume species plays a central role in the carbon metabolism in symbiotic root nodules, are activated through phosphorylation of a conserved residue by a specific protein kinase (PEPC-PK). Carbon 111-117 LjPEPC-PK Lotus japonicus 247-254 31520495-9 2020 Together, the results demonstrate that the SUT1-overexpressing plants with enhanced sucrose allocation to sinks adjust leaf carbon and nitrogen metabolism, and amino acid partitioning in order to accommodate the increased assimilate demand of growing seeds. Carbon 124-130 solute carrier family 13 member 4 Homo sapiens 43-47 32470665-0 2020 Fenton-driven oxidation of contaminant-spent granular activated carbon (GAC): GAC selection and implications. Carbon 64-70 glutaminase Homo sapiens 72-75 32470665-0 2020 Fenton-driven oxidation of contaminant-spent granular activated carbon (GAC): GAC selection and implications. Carbon 64-70 glutaminase Homo sapiens 78-81 32470665-1 2020 Raw materials, activation methods, and post-activation treatment used in manufacturing granular activated carbon (GAC) results in a spectrum of physicochemical characteristics that potentially impact the adsorption oxidation treatment process. Carbon 106-112 glutaminase Homo sapiens 114-117 31513829-11 2019 However, when MS animals were exposed to Poly (I:C), a more robust activation of Tlr3, Il6 and Nfkb1 gene transcription was observed in these mice compared with control animals. Carbon 49-50 toll-like receptor 3 Mus musculus 81-85 12643702-2 2003 The obtained carbon exhibited very high BET surface area and high pore volume. Carbon 13-19 delta/notch like EGF repeat containing Homo sapiens 40-43 31861818-9 2019 The aim of this review is to summarize current knowledge of the metabolic changes that occur during HSC activation with a particular focus on the retinol and lipid metabolism, the central carbon metabolism, and associated redox or stress-related signaling pathways. Carbon 188-194 fucosyltransferase 1 (H blood group) Homo sapiens 100-103 12929631-4 2003 Intramolecular addition of the newly incorporated carbonyl (C-19a) to the olefinic C-6 in ring B was achieved by means of a Prins reaction with TiCl4 as Lewis acid. Carbon 60-61 complement C6 Homo sapiens 83-86 31752488-3 2019 Adsorption isotherms have revealed that Co2-MOF is in the range of best CO2 adsorbents among the carbon materials, with a very large CO2/CH4 selectivity. Carbon 97-103 complement C2 Homo sapiens 40-43 32738418-4 2020 MATERIALS AND METHODS: The role of CYLD in PD-L1 expression was assessed by knockdown of CYLD in TET cells upon stimulation with interferon gamma (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha) or polyinosinic-polycytidylic acid (poly I:C). Carbon 35-36 CD274 molecule Homo sapiens 43-48 32538272-0 2020 Multi-walled carbon nanotubes induce IL-1beta secretion by activating hemichannels-mediated ATP release in THP-1 macrophages. Carbon 13-19 interleukin 1 alpha Homo sapiens 37-45 12627635-0 2003 The use of carbon thirteen nuclear magnetic resonance spectra to predict dioxin and furan binding affinities to the aryl hydrocarbon receptor. Carbon 11-17 aryl hydrocarbon receptor Homo sapiens 116-141 32672281-0 2020 A ratiometric fluorescent biosensor for the sensitive determination of alpha-glucosidase activity and acarbose based on N-doped carbon dots. Carbon 128-134 sucrase-isomaltase Homo sapiens 71-88 31703893-2 2019 In order to confirm key structural features to activate PPARalpha and/or PPARgamma, we have adopted structural modifications in the following parts: (i) the benzopyran core (hydrophobic nucleus) by benzopyran-4-one, dihydrobenzopyran or benzopyran-4-ol; (ii) the side chain at 2-position by shortening to C3, C4 and C5-carbons versus C-9-carbons of polycerasoidol; (iii) the carboxylic group (polar head) by oxygenated groups (hydroxyl, acetoxy, epoxide, ester, aldehyde) or non-oxygenated motifs (allyl and alkyl). Carbon 316-326 peroxisome proliferator activated receptor alpha Homo sapiens 56-65 31703893-2 2019 In order to confirm key structural features to activate PPARalpha and/or PPARgamma, we have adopted structural modifications in the following parts: (i) the benzopyran core (hydrophobic nucleus) by benzopyran-4-one, dihydrobenzopyran or benzopyran-4-ol; (ii) the side chain at 2-position by shortening to C3, C4 and C5-carbons versus C-9-carbons of polycerasoidol; (iii) the carboxylic group (polar head) by oxygenated groups (hydroxyl, acetoxy, epoxide, ester, aldehyde) or non-oxygenated motifs (allyl and alkyl). Carbon 334-345 peroxisome proliferator activated receptor alpha Homo sapiens 56-65 12482854-7 2003 Overexpression of LCE in cells resulted in the enhanced addition of two-carbon units to C12-C16 fatty acids, and evidence was provided that LCE catalyzed the initial condensation reaction of long chain fatty acid elongation. Carbon 72-78 ELOVL fatty acid elongase 6 Homo sapiens 18-21 31836717-4 2019 The distal and proximal ubiquitin moieties of Lys48-linked diubiquitin primarily interact with the C-terminal helix and N-terminal loop of the Npl4 C-terminal domain (CTD), respectively. Carbon 99-100 nuclear protein localization protein 4 Saccharomyces cerevisiae S288C 143-147 31836717-4 2019 The distal and proximal ubiquitin moieties of Lys48-linked diubiquitin primarily interact with the C-terminal helix and N-terminal loop of the Npl4 C-terminal domain (CTD), respectively. Carbon 148-149 nuclear protein localization protein 4 Saccharomyces cerevisiae S288C 143-147 31822672-0 2019 Author Correction: Tidal wetland resilience to sea level rise increases their carbon sequestration capacity in United States. Carbon 78-84 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 47-50 32974200-21 2020 Carbon-ion radiation could induce the highest CRT and PDL1 expression under normoxia. Carbon 0-6 CD274 molecule Homo sapiens 54-58 12590574-2 2003 The three-dimensional structure of (13)C-, (15)N-enriched human full-length apoCII in complex with sodium dodecyl sulfate (SDS) micelles is reported. Carbon 39-40 apolipoprotein C2 Homo sapiens 76-82 32388378-10 2020 Nevertheless, the overall dominance of terrestrial and marine SOM suggests that the sources of SOM and factors influencing carbon cycling in the Maowei Sea do not exclusively depend on the intensity of mariculture activities. Carbon 123-129 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 152-155 31835701-0 2019 Influence of Selected Carbon Nanostructures on the CYP2C9 Enzyme of the P450 Cytochrome. Carbon 22-28 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 51-57 31835701-5 2019 The objective of this study was to evaluate the influence of three carbon nanostructures on the activity and expression at the mRNA and protein levels of CYP2C9 isoenzyme from the CYP2C subfamily: Diamond nanoparticles, graphite nanoparticles, and graphene oxide platelets. Carbon 67-73 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 154-160 12604208-7 2003 The ADHVI expression was strongly induced when galactose was the sole carbon source in the culture medium. Carbon 70-76 NADP-dependent alcohol dehydrogenase Saccharomyces cerevisiae S288C 4-9 31835701-7 2019 A microsome model was used to assess the influence of the three-carbon nanostructures on the activity of the CYP2C9 isoenzyme. Carbon 64-70 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 109-115 31822614-5 2019 To this end, we analyzed the role of a conserved valine-proline (VP) motif in the C-terminal domain of CRY2 (CCT2), which resembles the core COP1-WD40-binding sequences present in the substrates of COP1. Carbon 82-83 phosphorylcholine cytidylyltransferase2 Arabidopsis thaliana 109-113 32803321-0 2020 "Turn-on" fluorometric probe for alpha-glucosidase activity using red fluorescent carbon dots and 3,3",5,5"-tetramethylbenzidine. Carbon 82-88 sucrase-isomaltase Homo sapiens 33-50 32803321-11 2020 Graphical Abstract Schematic of the method used to prepare the carbon dots and the mechanisms involved in determining alpha-glucosidase activity. Carbon 63-69 sucrase-isomaltase Homo sapiens 118-135 12438316-1 2003 Serine hydroxymethyltransferase (SHMT; EC 2.1.2.1) catalyzes the reversible interconversion of serine and glycine with transfer of the serine side chain one-carbon group to tetrahydropteroylglutamate (H(4)PteGlu), and also the conversion of 5,10-methenyl-H(4)PteGlu to 5-formyl-H(4)PteGlu. Carbon 157-163 serine hydroxymethyltransferase, cytosolic Oryctolagus cuniculus 0-31 32638759-0 2020 Microwave-assisted functionalization of carbon nanohorns with oligothiophene units with SERS activity. Carbon 40-46 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 88-92 31805132-10 2019 CONCLUSION: Treatment with a PPARalpha agonist influenced plasma concentration of one-carbon metabolites and markers of B-vitamin status. Carbon 86-92 peroxisome proliferator activated receptor alpha Rattus norvegicus 29-38 12438316-1 2003 Serine hydroxymethyltransferase (SHMT; EC 2.1.2.1) catalyzes the reversible interconversion of serine and glycine with transfer of the serine side chain one-carbon group to tetrahydropteroylglutamate (H(4)PteGlu), and also the conversion of 5,10-methenyl-H(4)PteGlu to 5-formyl-H(4)PteGlu. Carbon 157-163 serine hydroxymethyltransferase, cytosolic Oryctolagus cuniculus 33-37 31699690-4 2019 Abl2 uses its C-terminal half to bind MTs, an interaction mediated in part through electrostatic binding to tubulin C-terminal tails. Carbon 14-15 ABL proto-oncogene 2, non-receptor tyrosine kinase Homo sapiens 0-4 31699690-4 2019 Abl2 uses its C-terminal half to bind MTs, an interaction mediated in part through electrostatic binding to tubulin C-terminal tails. Carbon 116-117 ABL proto-oncogene 2, non-receptor tyrosine kinase Homo sapiens 0-4 32832317-0 2020 Gas sorption porosimetry for the evaluation of hard carbons as anodes for Li- and Na-ion batteries. Carbon 52-59 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 0-3 31699690-8 2019 These results show Abl2 uses its C-terminal half to bind MTs and directly regulate MT dynamics. Carbon 33-34 ABL proto-oncogene 2, non-receptor tyrosine kinase Homo sapiens 19-23 12530850-3 2003 In the solution photochemistry of C-6 monosubstituted enones in benzene, there was a unique preference for migration of the cis-phenyl group with formation of bicyclo[3.1.0]hexanone photoproducts, with the original 6-substituent having an endo configuration at carbon-3 of the product. Carbon 261-267 complement C6 Homo sapiens 34-37 32784787-1 2020 Gold nanoparticles (AuNPs) were homogeneously electrodeposited on nitrogen-doped reduced graphene oxide (N-rGO) to modify a glassy carbon electrode (GCE/N-rGO-Au) in order to improve the simultaneous detection of dopamine (DA), ascorbic acid (AA), and uric acid (UA). Carbon 131-137 aminomethyltransferase Homo sapiens 149-152 12521113-7 2003 Further analysis showed that the distribution coefficient (KD) increased with the particular organic carbon content of sediments, consistent with the PAH partition theory. Carbon 101-107 phenylalanine hydroxylase Homo sapiens 150-153 32903758-2 2020 We have previously shown that Polyriboinosinic-polyribocytidylic acid (poly I:C) induced maternal immune activation in mice caused histological changes in the hippocampal CA1 area of offspring during the developmental period and impaired sensorimotor gating in offspring during adulthood, resulting in behavioral changes. Carbon 78-79 carbonic anhydrase 1 Mus musculus 171-174 31675572-0 2019 Molecular and microbial insights towards understanding the anaerobic digestion of the wastewater from hydrothermal liquefaction of sewage sludge facilitated by granular activated carbon (GAC). Carbon 179-185 glutaminase Homo sapiens 187-190 31675572-3 2019 The present study showed that granular activated carbon (GAC) promoted the AD of HTLWW in continuous experiments, resulting in the higher methane yield (259 mL/g COD) compared to control experiment (202 mL/g COD). Carbon 49-55 glutaminase Homo sapiens 57-60 12521113-8 2003 The organic carbon normalised distribution coefficient (K(oc)) also increased with the compounds" octanol/water partition coefficient (K(ow)), confirming the potential applicability of the linear free energy relationships in the modelling and prediction of PAH behaviour in marine environments. Carbon 12-18 phenylalanine hydroxylase Homo sapiens 257-260 31541819-3 2019 The results suggested that the microbial biomass carbon, activity of denitrification enzyme and nitrogenase were indicative of MSI and MRS, and the same three parameters plus soil basal respiration were indicative of MRL. Carbon 49-55 RB binding protein 4, chromatin remodeling factor Homo sapiens 127-130 12507833-4 2003 A marked increase in the propensity of FA-modified CG 117-136 to form an alpha-helix structure was observed for the C-8, C-10 and C-12 derivatives compared with unmodified/short-chain and long-chain (C-14, C-16, C-18) derivatives. Carbon 51-52 homeobox C8 Homo sapiens 116-119 31154625-11 2019 Poly I:C stimulation increased mRNA expression of retinoic-acid-inducible protein I (RIG-I), melanoma-differentiation-associated gene 5 (MDA5), IFN-stimulated gene factor 3 (ISG3) complex, and IFN-stimulated genes (IRF7, ISG15, IFIT1, OAS1); nicotine attenuated mRNA expression only in WT cells. Carbon 7-8 interferon induced with helicase C domain 1 Homo sapiens 93-135 31154625-11 2019 Poly I:C stimulation increased mRNA expression of retinoic-acid-inducible protein I (RIG-I), melanoma-differentiation-associated gene 5 (MDA5), IFN-stimulated gene factor 3 (ISG3) complex, and IFN-stimulated genes (IRF7, ISG15, IFIT1, OAS1); nicotine attenuated mRNA expression only in WT cells. Carbon 7-8 interferon induced with helicase C domain 1 Homo sapiens 137-141 32367577-6 2020 The electrocatalyst loaded on carbon cloth electrode can afford a NH3 yield rate and faradaic efficiency of 32.1 mug h-1 mgcat.-1 (5350 mug h-1 mgFe-1) and 29.3%, respectively. Carbon 30-36 H1.5 linker histone, cluster member Homo sapiens 117-120 32367577-6 2020 The electrocatalyst loaded on carbon cloth electrode can afford a NH3 yield rate and faradaic efficiency of 32.1 mug h-1 mgcat.-1 (5350 mug h-1 mgFe-1) and 29.3%, respectively. Carbon 30-36 H1.5 linker histone, cluster member Homo sapiens 140-143 32367577-7 2020 An exceptional NH3 yield rate of 307.7 mug h-1 mgcat.-1 (51,283 mug h-1 mgFe-1) with a near record faradaic efficiency of 51.0% can be achieved from the electrocatalyst immobilized on a glassy carbon electrode. Carbon 193-199 H1.5 linker histone, cluster member Homo sapiens 43-46 32367577-7 2020 An exceptional NH3 yield rate of 307.7 mug h-1 mgcat.-1 (51,283 mug h-1 mgFe-1) with a near record faradaic efficiency of 51.0% can be achieved from the electrocatalyst immobilized on a glassy carbon electrode. Carbon 193-199 H1.5 linker histone, cluster member Homo sapiens 68-71 31444411-3 2019 Here, we report that the gene encoding glycine decarboxylase (GLDC), which catalyzes the first and rate-limiting step in glycine breakdown with the production of the one-carbon unit 5,10-methylene-tetrahydrofolate, is a direct transcriptional target of MYCN. Carbon 170-176 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 253-257 12444972-12 2002 Based on the above results, we propose that Mrg19p is a regulator of galactose and nonfermentable carbon utilization. Carbon 98-104 Csr2p Saccharomyces cerevisiae S288C 44-50 31615848-0 2019 Genetic Analyses of the Arabidopsis ATG1 Kinase Complex Reveal Both Kinase-Dependent and Independent Autophagic Routes during Fixed-Carbon Starvation. Carbon 132-138 transmembrane protein G1P-related 1 Arabidopsis thaliana 36-40 31615848-4 2019 These isoforms appear to act redundantly, including the plant-specific, truncated ATG1t variant, and like other well-characterized atg mutants, homozygous atg1abct plants display early leaf senescence and hypersensitivity to nitrogen and fixed-carbon starvation. Carbon 244-250 transmembrane protein G1P-related 1 Arabidopsis thaliana 155-159 31615848-5 2019 Although the ATG1 kinase is essential for up-regulating autophagy under nitrogen deprivation and short-term carbon starvation, it did not stimulate autophagy under prolonged carbon starvation. Carbon 108-114 transmembrane protein G1P-related 1 Arabidopsis thaliana 13-17 31430731-0 2019 NiFeP nanoflakes composite with CoP on carbon cloth as flexible and durable electrocatalyst for efficient overall water splitting. Carbon 39-45 caspase recruitment domain family member 16 Homo sapiens 32-35 31430731-1 2019 High-performance and earth-abundant NiFeP is an excellent bifunctional catalyst for water splitting in acidic and alkaline environments, and NiFeP nanoflakes on CoP layer composite with a conductive carbon cloth (CC) substrate as the trunk-leaf flexible structure (NiFeP/CoP/CC) is prepared by direct high-temperature phosphorization. Carbon 199-205 caspase recruitment domain family member 16 Homo sapiens 161-164 32305864-4 2020 Herein, we developed an in vivo electrochemical immunosensing device based on glassy carbon rod to simultaneously detect three proinflammatory cytokines (IL-1beta, IL-6 and TNF-alpha). Carbon 85-91 interleukin 1 alpha Homo sapiens 154-162 32752305-0 2020 Cellulose-Based Carbon Molecular Sieve Membranes for Gas Separation: A Review. Carbon 16-22 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 53-56 12447538-4 2002 This observation suggests that, in conjunction with GS, GDH plays a major role in controlling the translocation of organic carbon and nitrogen metabolites in both vegetative and reproductive organs. Carbon 123-129 L-galactose dehydrogenase Vitis vinifera 56-59 31698896-1 2019 The oxidative addition of organic electrophiles into electrochemically generated Co(I) complexes has been widely utilized as a strategy to produce carbon-centered radicals when cobalt is ligated by a polydentate ligand. Carbon 147-153 mitochondrially encoded cytochrome c oxidase I Homo sapiens 81-86 12447538-6 2002 Although the function of such organelles is still unknown, its is possible that the presence of GDH in such cellular structures is important for the recycling of carbon and nitrogen molecules in senescing tissues in which the enzyme is generally induced. Carbon 162-168 L-galactose dehydrogenase Vitis vinifera 96-99 12408937-10 2002 Rather, the use of relatively high amounts ( approximately 10 wt.%) of the labeled SP-C protein is needed to reproduce the fluorescence monolayer morphology previously observed for small concentrations ( approximately 1 wt.%) of the natural SP-B/C mixture. Carbon 86-87 surfactant protein B Homo sapiens 241-245 31885801-8 2019 Furthermore, we report on a C-terminal truncation of HO-1, which is generally considered as a signal molecule. Carbon 28-29 heme oxygenase 1 Homo sapiens 53-57 31617346-6 2019 We map these antifibrillar attributes to the central region and C-terminal domain of SCGN, while the N-terminal domain is not essential for this activity. Carbon 64-65 secretagogin, EF-hand calcium binding protein Homo sapiens 85-89 32579488-3 2022 The role of ERT and renewable energy in reducing carbon emissions is investigated in a panel of seven emerging economies during 1990-2016 in the "Environment Kuznets Curve (EKC)" framework. Carbon 49-55 E74 like ETS transcription factor 3 Homo sapiens 12-15 32579488-5 2022 Findings suggest the supportive role of environment-related technologies in the presence of renewable energy in reducing carbon emissions. Carbon 121-127 E74 like ETS transcription factor 3 Homo sapiens 40-72 32222061-3 2020 Herein, we developed a simple strategy to integrate 2D/0D CoP in the same MOF precursor-derived hollow N-doped carbon nanotube-assembled polyhedron. Carbon 111-117 caspase recruitment domain family member 16 Homo sapiens 58-61 32640591-3 2020 In setting out to build vacuum-free and carbon-based all-inorganic PSCs with the traits of simple fabrication and low cost, we propose the ones with a simplified vertical structure of FTO/CsPbIBr2/carbon upon interfacial modification with PEI species. Carbon 40-46 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 184-187 12454062-1 2002 In the yeast Saccharomyces cerevisiae, certain mutant alleles of YME4, YME6, and MDM10 cause an increased rate of mitochondrial DNA migration to the nucleus, carbon-source-dependent alterations in mitochondrial morphology, and increased rates of mitochondrial DNA loss. Carbon 158-164 ERMES complex subunit MMM1 Saccharomyces cerevisiae S288C 71-75 31445446-2 2019 Here, the intrinsically disordered protein alpha-synuclein is explored as a dispersant of single-walled carbon nanotubes (SWNTs) in water. Carbon 104-110 synuclein alpha Homo sapiens 43-58 31472317-2 2019 Herein, a three-dimensional (3D) structural material in which amorphous carbon (AC) encapsulated CoP nanoparticles are embedded at the top of nitrogen-doped carbon nanotubes derived from ZIF-67/ZIF-8 grown on the surface of carbon nanofibers (AC@CoP/NCNTs/CNFs) is reported for the first time. Carbon 72-78 caspase recruitment domain family member 16 Homo sapiens 97-100 32330361-3 2020 We report a concise synthesis of C-3 substituted derivatives of pyridine-2,4-dicarboxylic acid (2,4-PDCA) as 2OG competitors for use in SAR studies on AspH inhibition. Carbon 33-34 aspartate beta-hydroxylase Homo sapiens 151-155 12454062-4 2002 Yeast strains bearing null mutations of MMM1 have altered mitochondrial morphology and a slow growth rate on all carbon sources and quantitatively lack mitochondrial DNA. Carbon 113-119 ERMES complex subunit MMM1 Saccharomyces cerevisiae S288C 40-44 32330361-5 2020 Certain C-3 substituted 2,4-PDCA derivatives were potent AspH inhibitors, manifesting selectivity over some, but not all, other tested human 2OG oxygenases. Carbon 0-1 aspartate beta-hydroxylase Homo sapiens 57-61 12409271-4 2002 We used the [1,2-13C2]D-glucose tracer and gas chromatography/mass spectrometry to characterize glucose carbon redistribution between the nucleic acid ribose, lactate, and palmitate synthetic pathways, and reverse transcriptase-polymerase chain reaction to assess adipose differentiation related protein (ADRP) mRNA expression in response to hyperoxic exposure. Carbon 104-110 perilipin 2 Rattus norvegicus 264-303 32678639-2 2020 Our theoretical investigations clarified that the pentagonal covalent network is a metastable three-dimensional carbon allotrope with the Fm3[over ]m space group possessing remarkable mechanical properties: relatively high bulk modulus of 381 GPa together with a negative Poisson"s ratio of -0.241. Carbon 112-118 neuromedin U receptor 1 Homo sapiens 138-141 31717548-0 2019 Antitumor Reactive T-Cell Responses Are Enhanced In Vivo by DAMP Prothymosin Alpha and Its C-Terminal Decapeptide. Carbon 21-22 prothymosin alpha pseudogene 9 Homo sapiens 65-82 31717548-1 2019 Prothymosin alpha (proTalpha) and its C-terminal decapeptide proTalpha(100-109) were shown to pleiotropically enhance innate and adaptive immune responses. Carbon 38-39 prothymosin alpha pseudogene 9 Homo sapiens 0-29 12409271-4 2002 We used the [1,2-13C2]D-glucose tracer and gas chromatography/mass spectrometry to characterize glucose carbon redistribution between the nucleic acid ribose, lactate, and palmitate synthetic pathways, and reverse transcriptase-polymerase chain reaction to assess adipose differentiation related protein (ADRP) mRNA expression in response to hyperoxic exposure. Carbon 104-110 perilipin 2 Rattus norvegicus 305-309 31603662-2 2019 Here, by selecting appreciate precursors of dopamine and a Co-containing metal-organic framework of ZIF-67, we subtly couple their reaction processes to develop a facile approach for the synthesis of a hollow CoP nanostructure with N-doped carbon skeleton (H-CoP@NC). Carbon 240-246 caspase recruitment domain family member 16 Homo sapiens 209-212 31603662-3 2019 Benefiting from the highly porous nanostructure and conductive carbon skeleton, H-CoP@NC is capable of working as highly active and durable bifunctional electrocatalyst for both hydrogen and oxygen evolution reaction. Carbon 63-69 caspase recruitment domain family member 16 Homo sapiens 82-85 32832363-3 2020 In this study, Gd3+ and chlorin e6 loaded single-walled carbon nanohorns (Gd-Ce6@SWNHs) are developed, and it is demonstrated that they are a strong immune adjuvant, and have high tumor targeting and penetration efficiency. Carbon 56-62 GRDX Homo sapiens 15-18 12526206-3 2002 The Gsh+ transformants of the gsh1 and gsh2 mutants, which bear plasmids pG1 and pG24 with the 7.2- and 4.3-kbp DNA fragments, respectively, had a completely restored wild-type phenotype with the ability to synthesize GSH and to grow in GSH-deficient synthetic media on various carbon sources, including methanol, and with acquired tolerance to cadmium ions. Carbon 278-284 glutathione synthase Saccharomyces cerevisiae S288C 39-43 31544921-4 2019 We identified an internal interaction between the WD40 propeller and the C-terminal distal region in RBBP5, which assisted the maintenance of the compact conformation of the MLL1 complex. Carbon 73-74 lysine methyltransferase 2A Homo sapiens 174-178 31544921-5 2019 We also discovered a vertebrate-specific motif in the C-terminal distal region of RBBP5 that contributed to nucleosome recognition and methylation of nucleosomes by the MLL1 complex. Carbon 54-55 lysine methyltransferase 2A Homo sapiens 169-173 12356470-8 2002 Under these conditions, the GAL1 promoter is no longer repressed due to exhaustion of glucose and utilization of ethanol as a carbon source. Carbon 126-132 galactokinase Saccharomyces cerevisiae S288C 28-32 31422301-5 2019 Consequently high total organic carbon and emerging hypoxia in the Gulf may lead to expansion/intensification of the oxygen minimum zone of the Arabian Sea. Carbon 32-38 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 152-155 32301087-0 2020 Spatial variability of sedimentary carbon in South Yellow Sea, China: impact of anthropogenic emission and long-range transportation. Carbon 35-41 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 58-61 31657158-6 2019 The immunoactivity of TNF-alpha and IL-10 of the dorsal portion of the cervical spinal cord (C2-C5) was detected by immunofluorescence, and the expression of TNF-alpha, IL-10, IL-4 and IL-4 receptor (IL-4R) mRNAs was determined by quantitative real-time PCR. Carbon 93-98 interleukin 10 Rattus norvegicus 36-41 12366798-0 2002 An engineered phosphoenolpyruvate carboxylase redirects carbon and nitrogen flow in transgenic potato plants. Carbon 56-62 phosphoenolpyruvate carboxylase Solanum tuberosum 14-45 31649237-2 2019 Here, we report an atomically dispersed Ru1-N4 site anchored on nitrogen-carbon support (Ru-N-C) as an efficient and durable electrocatalyst for acidic OER. Carbon 64-79 Scm like with four mbt domains 1 Homo sapiens 40-43 32573211-4 2020 A series of strong bond (C-C and C-H) cleavages convert the C5 gem-dimethyl group to the C15 lactone of PXN. Carbon 25-26 paxillin Homo sapiens 104-107 32573211-4 2020 A series of strong bond (C-C and C-H) cleavages convert the C5 gem-dimethyl group to the C15 lactone of PXN. Carbon 27-28 paxillin Homo sapiens 104-107 32573211-4 2020 A series of strong bond (C-C and C-H) cleavages convert the C5 gem-dimethyl group to the C15 lactone of PXN. Carbon 27-28 paxillin Homo sapiens 104-107 12366798-1 2002 Phosphoenolpyruvate carboxylase (PEPC) plays a central role in the anaplerotic provision of carbon skeletons for amino acid biosynthesis in leaves of C3 plants. Carbon 92-98 phosphoenolpyruvate carboxylase Solanum tuberosum 0-31 31624245-4 2019 Moreover, we found that MYCN mediated the folate cycle via MTHFD2, which contributed one-carbon unit to enhance purine synthesis, and further regulated nucleotide production by PAICS in response to cancer progression. Carbon 89-95 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 24-28 12366798-1 2002 Phosphoenolpyruvate carboxylase (PEPC) plays a central role in the anaplerotic provision of carbon skeletons for amino acid biosynthesis in leaves of C3 plants. Carbon 92-98 phosphoenolpyruvate carboxylase Solanum tuberosum 33-37 12236755-10 2002 At catalytic conditions, the calculated free energies of C-H addition are 31.3 and 33.7 kcal/mol for CyH and n-PrH addition, respectively. Carbon 57-58 hematopoietically expressed homeobox Homo sapiens 111-114 31623126-1 2019 In the present study, a sensitive and selective impedimetric detection of solution-phase nucleic acid hybridization related to Factor V Leiden (FV Leiden) mutation was performed by carbon nanofibers (CNF) modified screen printed electrodes (SPE). Carbon 181-187 coagulation factor V Homo sapiens 127-142 31623126-1 2019 In the present study, a sensitive and selective impedimetric detection of solution-phase nucleic acid hybridization related to Factor V Leiden (FV Leiden) mutation was performed by carbon nanofibers (CNF) modified screen printed electrodes (SPE). Carbon 181-187 coagulation factor V Homo sapiens 144-153 12226529-2 2002 Arabidopsis CYP90B1/DWF4 and CYP90A1/CPD are responsible for respective C-22 and C-23 hydroxylation of the steroid side chain and CYP85A1 catalyzes C-6 oxidation of 6-deoxo intermediates, whereas the functions of CYP90C1/ROT3, CYP90D1, and CYP85A2 are still unknown. Carbon 12-13 brassinosteroid-6-oxidase 1 Arabidopsis thaliana 130-137 12226529-2 2002 Arabidopsis CYP90B1/DWF4 and CYP90A1/CPD are responsible for respective C-22 and C-23 hydroxylation of the steroid side chain and CYP85A1 catalyzes C-6 oxidation of 6-deoxo intermediates, whereas the functions of CYP90C1/ROT3, CYP90D1, and CYP85A2 are still unknown. Carbon 12-13 brassinosteroid-6-oxidase 2 Arabidopsis thaliana 240-247 31581160-1 2019 BACKGROUND Serine hydroxymethyltransferase (SHMT) is the enzyme that catalyzes the reversible conversion of serine to glycine and tetrahydrofolate-bound one-carbon unit. Carbon 157-163 serine hydroxymethyltransferase 1 Homo sapiens 11-42 12226529-2 2002 Arabidopsis CYP90B1/DWF4 and CYP90A1/CPD are responsible for respective C-22 and C-23 hydroxylation of the steroid side chain and CYP85A1 catalyzes C-6 oxidation of 6-deoxo intermediates, whereas the functions of CYP90C1/ROT3, CYP90D1, and CYP85A2 are still unknown. Carbon 29-30 brassinosteroid-6-oxidase 1 Arabidopsis thaliana 130-137 31581160-1 2019 BACKGROUND Serine hydroxymethyltransferase (SHMT) is the enzyme that catalyzes the reversible conversion of serine to glycine and tetrahydrofolate-bound one-carbon unit. Carbon 157-163 serine hydroxymethyltransferase 1 Homo sapiens 44-48 12226529-2 2002 Arabidopsis CYP90B1/DWF4 and CYP90A1/CPD are responsible for respective C-22 and C-23 hydroxylation of the steroid side chain and CYP85A1 catalyzes C-6 oxidation of 6-deoxo intermediates, whereas the functions of CYP90C1/ROT3, CYP90D1, and CYP85A2 are still unknown. Carbon 29-30 brassinosteroid-6-oxidase 2 Arabidopsis thaliana 240-247 31582797-5 2019 HERC2 interacted with RPA through the C-terminal HECT domain. Carbon 3-4 replication protein A1 Homo sapiens 22-25 12127539-6 2002 Low but significant phosphorylation rates in the range of 0.18% that of thymidine were observed for the carbon-linked 3"-carboranyl thymidine analogues in phosphoryl transfer assays using recombinant preparations of thymidine kinases 1 (TK1) and thymidine kinases 2 (TK2). Carbon 104-110 thymidine kinase 2 Homo sapiens 267-270 31307579-4 2019 Change in these phenotypic traits of the organism may be attributed to multi-level modulation in central carbon metabolism e.g., upregulation of glycolytic pathway; upregulation in thiolase activity; key intermediate enzyme for biosynthesis of acids and solvent; upregulation in the activity of butyrylaldehyde dehydrogenase & butanol dehydrogenase, the enzymes responsible for butanol biosynthesis and downregulation in alcohol dehydrogenase, redirecting carbon flux from ethanol to butanol. Carbon 105-111 CA_P0059 Clostridium acetobutylicum ATCC 824 421-442 31681792-3 2019 In order to better understand the domain dynamics comparative Molecular Dynamics (MD) simulations of a sub-structure of Hsp90, the dimer formed by the middle (M) and C-terminal domain (C), were performed. Carbon 166-167 Hsp90 family chaperone HSP82 Saccharomyces cerevisiae S288C 120-125 11997326-2 2002 Here, we cultured HeLa cells that stably expressed human PGT under conditions known to favor glycolysis (glucose as a carbon source) or oxidative phosphorylation (glutamine as a carbon source) and studied the effect on PGT-mediated [(3)H]PGE(2) influx. Carbon 118-124 solute carrier organic anion transporter family member 2A1 Homo sapiens 57-60 31572445-7 2019 Of all the currently reported NM-causing LMOD3 nonsense and frameshifting variants, c.1412delA generates the shortest truncation at the C-terminal end of the protein, underscoring the critical role of the WH2 domain in LMOD3 structure and function. Carbon 136-137 leiomodin 3 Homo sapiens 41-46 11997326-2 2002 Here, we cultured HeLa cells that stably expressed human PGT under conditions known to favor glycolysis (glucose as a carbon source) or oxidative phosphorylation (glutamine as a carbon source) and studied the effect on PGT-mediated [(3)H]PGE(2) influx. Carbon 178-184 solute carrier organic anion transporter family member 2A1 Homo sapiens 57-60 11960421-3 2002 The carbon atoms of the C82 cage were individually identified and refined with only a constraint that required the two halves of the cage to possess similar bond lengths. Carbon 4-10 complement C8 beta chain Homo sapiens 24-27 31402666-0 2019 In Situ SERS Detection of Photocatalytic Degradation of Aminothiophenol on Carbon-Nanotubes/CoPt Hollow Nanoparticles Composite. Carbon 75-81 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 8-12 30442817-3 2019 Genetic variants in vitamin C transporter proteins (SLC23A1), especially rs33972313, may provide evidence on a causal association of vitamin C with cataract. Carbon 28-29 solute carrier family 23 member 1 Homo sapiens 52-59 32689468-0 2002 Regulation of a carbon concentrating mechanism through CCM1 in Chlamydomonas reinhardtii. Carbon 16-22 uncharacterized protein Chlamydomonas reinhardtii 55-59 31158745-4 2019 From in vitro binding assay using recombinant Tau aggregates, complex 4.2 with 6-N(CH3)2 and longer carbon chain (n = 4) displayed the highest affinity (Kd = 59.95 nM). Carbon 100-106 microtubule associated protein tau Homo sapiens 46-49 12028661-6 2002 The calculated nucleophilic susceptibility of the aromatic carbon para to the amino group (NS4) was the most significant parameter for determining oxanilic acid formation following N-acetylation. Carbon 59-65 SOS Ras/Rac guanine nucleotide exchange factor 1 Homo sapiens 91-94 30961713-0 2019 Tip and Inner Wall Modification of 4.9 nm Diameter Multi-Walled Carbon Nanotubes and Its Nanocomposite Polyamide Reverse Osmosis Membrane. Carbon 64-70 TOR signaling pathway regulator Homo sapiens 0-3 30961713-1 2019 The tip and inner surface of large diameter multi-walled carbon nanotubes (MWCNTs) (4.9 nm diameter) were functionalized on the tip and inner surface to improve the rate of desalination and maintain high water flux. Carbon 57-63 TOR signaling pathway regulator Homo sapiens 4-7 30961713-1 2019 The tip and inner surface of large diameter multi-walled carbon nanotubes (MWCNTs) (4.9 nm diameter) were functionalized on the tip and inner surface to improve the rate of desalination and maintain high water flux. Carbon 57-63 TOR signaling pathway regulator Homo sapiens 128-131 11782424-5 2002 The steady-state levels of COX in the revertants is increased by a factor of 4-5, accounting for their ability to respire and grow on non-fermentable carbon sources at nearly wild-type rates. Carbon 150-156 cytochrome c oxidase subunit 8A Homo sapiens 27-30 31177362-1 2019 Sideroflexin 1 (Sfxn1) is a mitochondrial serine transporter involved in one-carbon metabolism in blood and cancer cell lines. Carbon 77-83 sideroflexin 1 Homo sapiens 0-14 31177362-1 2019 Sideroflexin 1 (Sfxn1) is a mitochondrial serine transporter involved in one-carbon metabolism in blood and cancer cell lines. Carbon 77-83 sideroflexin 1 Homo sapiens 16-21 11755253-2 2002 Since the sites for tyrosine phosphorylation and nitration are on adjacent carbon atoms, the present study tested the hypothesis that in vitro dephosphorylation of the NR1, NR2A and NR2B subunits of the NMDA receptor increases receptor nitration by peroxynitrite in cortical membranes of newborn piglets. Carbon 75-81 glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens 182-186 31328875-0 2019 Bio-Derived Co2 P Nanoparticles Supported on Nitrogen-Doped Carbon as Promising Oxygen Reduction Reaction Electrocatalyst for Anion Exchange Membrane Fuel Cells. Carbon 60-66 complement C2 Homo sapiens 12-15 31328875-2 2019 In this work, Co2 P nanoparticles supported on heteroatom-doped carbon catalysts (NBSCP) are developed with an eco-friendly synthesis method using bean sprouts. Carbon 64-70 complement C2 Homo sapiens 14-17 12180649-6 2002 By observing the chemical structures of compounds belonging to the first group we can see that less cytotoxic activities are related to the presence of a 3beta-hydroxy group on C-3 (ring A) and a double bond between C-22 and C-23 (side chain). Carbon 177-178 nucleolin Homo sapiens 225-229 31361084-2 2019 Herein, hierarchically porous W-doped CoP nanoflake arrays on carbon cloth (W-CoP NAs/CC) are synthesized via facile liquid-phase reactions and a subsequent phosphorization process. Carbon 62-68 caspase recruitment domain family member 16 Homo sapiens 38-41 12180649-6 2002 By observing the chemical structures of compounds belonging to the first group we can see that less cytotoxic activities are related to the presence of a 3beta-hydroxy group on C-3 (ring A) and a double bond between C-22 and C-23 (side chain). Carbon 216-217 nucleolin Homo sapiens 225-229 12194341-7 2002 The biological therapeutic gain would be high for the carbon ion SOBP if the number of fractions were correctly selected in clinical trials. Carbon 54-60 sine oculis binding protein Mus musculus 65-69 31555090-8 2019 However, a monoclonal antibody (CB-beta-1) recognized CaMKII-beta but also cross-reacted with the C-terminal tail of Cx36, making localization analyses with this antibody inaccurate. Carbon 32-33 calcium/calmodulin-dependent protein kinase II gamma Mus musculus 54-60 12404496-0 2001 [12.12]Paracyclophanedodecaynes C(36)H(8) and C(36)Cl(8): The Smallest Paracyclophynes and Their Transformation into the Carbon Cluster Ion C(36)(-) This work was supported in part by Grants-in-Aid for Scientific Research from the Ministry of Education,Science,Sports and Culture of Japan. Carbon 121-127 activation induced cytidine deaminase Homo sapiens 194-197 31440836-2 2019 The fluorescence of the N/Ce co-doped carbon dots (CDN/Ce) is strongest. Carbon 38-44 5', 3'-nucleotidase, cytosolic Homo sapiens 51-54 31434956-0 2019 Prolonged exposure to multi-walled carbon nanotubes dysregulates intestinal mir-35 and its direct target MAB-3 in nematode Caenorhabditis elegans. Carbon 35-41 Protein male abnormal 3 Caenorhabditis elegans 105-110 31438613-6 2019 Therefore, the CC1 electrode using copper film with type 1 carbon tape was determined to be the best alternative to the conventional CS electrode. Carbon 59-65 C-C motif chemokine ligand 14 Homo sapiens 15-18 11448685-4 2001 The data, correlated with previous literature results, clearly show that at pH 2.5 the production of carbon dioxide from C-6 and C-1 carbon atoms is nearly equivalent. Carbon 101-107 complement C6 Homo sapiens 121-124 31152833-5 2019 To build a voltammetric sensor (Chitosan-Ag NPs/CPE), a carbon paste electrode has immersed in the liquid suspension of chitosan-Ag NPs, thus, it could be employed for electro-catalytic reduction of 4-NA in 0.1 M Britton-Robinson buffer solution (B-R, pH 2). Carbon 56-62 carboxypeptidase E Homo sapiens 48-51 31755194-5 2020 We demonstrated that the third EF-hand domain of CaM7 specifically interacts with the cytosolic C-terminal domain of CNGC14. Carbon 49-50 cyclic nucleotide-gated channel 14 Arabidopsis thaliana 117-123 32350077-0 2020 Catalytic residues, substrate specificity, and role in carbon starvation of the 2-hydroxy FA dioxygenase Mpo1 in yeast. Carbon 55-61 Mpo1p Saccharomyces cerevisiae S288C 105-109 31243089-3 2019 Macrophages from TAK1-deficient mice underwent cell death in response to LPS and poly(I:C), which took place in a manner dependent on TLR/TRIF-induced active Caspase8-mediated cleavage of gasdermin D, known as an executioner of pyroptosis. Carbon 88-89 ring finger protein 138 Mus musculus 138-142 11444938-11 2001 For deuterons attached to sp2 carbons, first, the asymmetry factors eta and, second, the quadrupole coupling constants C(Q), are unusually small, eta1=0.018, eta2=0.011, and C(Q1)=(151.27+/-0.06) kHz, C(Q2)=(154.09+/-0.06) kHz. Carbon 30-37 endothelin receptor type A Homo sapiens 68-71 31243089-3 2019 Macrophages from TAK1-deficient mice underwent cell death in response to LPS and poly(I:C), which took place in a manner dependent on TLR/TRIF-induced active Caspase8-mediated cleavage of gasdermin D, known as an executioner of pyroptosis. Carbon 88-89 caspase 8 Mus musculus 158-166 31294440-5 2019 On the other hand, the decrease in the interlayer distances (compressive strains) can transform graphene/MTe into semiconductors, which originates from graphene/MTe with a large compressive strain that makes the two carbon sublattices inequivalent, inducing a band gap. Carbon 216-222 metallothionein 1I, pseudogene Homo sapiens 105-108 31294440-5 2019 On the other hand, the decrease in the interlayer distances (compressive strains) can transform graphene/MTe into semiconductors, which originates from graphene/MTe with a large compressive strain that makes the two carbon sublattices inequivalent, inducing a band gap. Carbon 216-222 metallothionein 1I, pseudogene Homo sapiens 161-164 11412986-2 2001 The synthesis of a nonhydrolyzable, carbon-linked analogue (4-HBR) of the retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) using Umpolung methods is described. Carbon 36-42 haptoglobin-related protein Homo sapiens 116-119 31381950-9 2019 Overall, this study suggests that the fetal liver Mll-AF4+ LSK cells are sensitive to direct exposure to inflammatory stimuli, especially poly(I:C); however, maternal immune activation induced by a single exposure to poly(I:C) is not sufficient to initiate MLL-AF4 leukemogenesis. Carbon 145-147 AF4/FMR2 family, member 1 Mus musculus 54-57 32319660-0 2020 The effects of the Wnt/beta-catenin signaling pathway on apoptosis in HeLa cells induced by carbon ion irradiation. Carbon 92-98 catenin beta 1 Homo sapiens 23-35 32319660-2 2020 The aim of this study was to explore the Wnt/beta-catenin pathway in regulating carbon ion (12C6+) radiation-induced cellular toxicity. Carbon 80-86 catenin beta 1 Homo sapiens 45-57 31865509-8 2020 Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space. Carbon 120-121 K+ efflux antiporter 1 Arabidopsis thaliana 57-61 31865509-8 2020 Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space. Carbon 120-121 K+ efflux antiporter 1 Arabidopsis thaliana 131-135 31865509-8 2020 Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space. Carbon 120-121 K+ efflux antiporter 1 Arabidopsis thaliana 131-135 31865509-8 2020 Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space. Carbon 194-195 K+ efflux antiporter 1 Arabidopsis thaliana 57-61 31865509-8 2020 Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space. Carbon 194-195 K+ efflux antiporter 1 Arabidopsis thaliana 131-135 31233051-0 2019 MOF derived CoP-decorated nitrogen-doped carbon polyhedrons/reduced graphene oxide composites for high performance supercapacitors. Carbon 41-47 caspase recruitment domain family member 16 Homo sapiens 12-15 11319814-2 2001 The reaction catalyzed by ETA involves the nucleophilic attack of the diphthamide residue on the anomeric carbon of the nicotinamide ribose forming a new glycosidic bond. Carbon 106-112 endothelin receptor type A Homo sapiens 26-29 31233051-1 2019 ZIF-67 derived CoP-decorated nitrogen-doped porous carbon (CoP-NPC) polyhedra anchored on reduced graphene oxide (RGO) sheets have been successfully prepared through an efficient pyrolysis-phosphidation-assembly strategy. Carbon 51-57 caspase recruitment domain family member 16 Homo sapiens 15-18 31233051-4 2019 This superior electrochemical performance of CoP-NPC/RGO can be ascribed to its 3D interconnected porous structure and the synergistic effect between CoP and the nitrogen-doped carbon matrix. Carbon 177-183 caspase recruitment domain family member 16 Homo sapiens 45-48 32022960-2 2020 The FRI protein regulates flowering induction by binding partner proteins on its N- and C-terminus domains and creating a supercomplex that promotes transcription of the floral repressor FLC. Carbon 88-89 FRIGIDA-like protein Arabidopsis thaliana 4-7 11287669-0 2001 Ccm1, a regulatory gene controlling the induction of a carbon-concentrating mechanism in Chlamydomonas reinhardtii by sensing CO2 availability. Carbon 55-61 uncharacterized protein Chlamydomonas reinhardtii 0-4 32470287-3 2020 Herein, under the support of theoretical calculation that the heterointerfaces between CoP and Pd can reduce the energy barrier of C-C bond cleavage, rich heterointerfaces in CoP/RGO-Pd hybrids were designed to improve ethanol electrooxidation performance through enhancing the selectivity towards C1 pathway. Carbon 87-88 caspase recruitment domain family member 16 Homo sapiens 175-178 32470287-3 2020 Herein, under the support of theoretical calculation that the heterointerfaces between CoP and Pd can reduce the energy barrier of C-C bond cleavage, rich heterointerfaces in CoP/RGO-Pd hybrids were designed to improve ethanol electrooxidation performance through enhancing the selectivity towards C1 pathway. Carbon 131-132 caspase recruitment domain family member 16 Homo sapiens 87-90 32470287-3 2020 Herein, under the support of theoretical calculation that the heterointerfaces between CoP and Pd can reduce the energy barrier of C-C bond cleavage, rich heterointerfaces in CoP/RGO-Pd hybrids were designed to improve ethanol electrooxidation performance through enhancing the selectivity towards C1 pathway. Carbon 131-132 caspase recruitment domain family member 16 Homo sapiens 175-178 31022583-2 2019 Herein, a series of Cucurbitacin inspired estrone analogs was assembled to generate 18 novel synthesized analogs via installation of double bond across C-16/C-17 positions of estrone scaffold and diastereomeric separation of (R) and (S) at C-20. Carbon 20-21 cytokine like 1 Homo sapiens 157-161 31022583-2 2019 Herein, a series of Cucurbitacin inspired estrone analogs was assembled to generate 18 novel synthesized analogs via installation of double bond across C-16/C-17 positions of estrone scaffold and diastereomeric separation of (R) and (S) at C-20. Carbon 152-153 cytokine like 1 Homo sapiens 157-161 31127856-1 2019 Serine hydroxymethyltransferase (SHMT) is the major source of 1-carbon units required for nucleotide synthesis. Carbon 64-70 serine hydroxymethyltransferase 1 Homo sapiens 0-31 31127856-1 2019 Serine hydroxymethyltransferase (SHMT) is the major source of 1-carbon units required for nucleotide synthesis. Carbon 64-70 serine hydroxymethyltransferase 1 Homo sapiens 33-37 32556737-0 2020 Ratiometric fluorescent test pen filled with a mixing ink of carbon dots and CdTe quantum dots for portable assay of silver ion on paper. Carbon 61-67 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 29-32 11287669-5 2001 Introduction of Ccm1 into this mutant restored an active carbon transport through the CCM, development of a pyrenoid structure in the chloroplast, and induction of a set of CCM-related genes. Carbon 57-63 uncharacterized protein Chlamydomonas reinhardtii 16-20 30986666-8 2019 Over longer periods, StSp consortium managed to completely decolorize RB-5 (50 mg/L) at optimized conditions of 25-30 C, pH 9, and using glucose and NH4H2PO4 as carbon and nitrogen source respectively, whereas PsGo consortium decolorized RB-5 (50 mg/mL) completely at 37 C, pH 11, and with lactose and NH4H2PO4 used as carbon and nitrogen sources. Carbon 162-168 steroid sulfatase Homo sapiens 21-25 11301459-0 2001 A Seven-Membered Carbon-Ring-Fused Phthalocyanine Analogue in which the pi System Changes during Dehydrogenation/Hydrogenation Cycles This research was supported by a Grant-in-Aid for Scientific Research (B) No. Carbon 17-23 activation induced cytidine deaminase Homo sapiens 176-179 30986666-8 2019 Over longer periods, StSp consortium managed to completely decolorize RB-5 (50 mg/L) at optimized conditions of 25-30 C, pH 9, and using glucose and NH4H2PO4 as carbon and nitrogen source respectively, whereas PsGo consortium decolorized RB-5 (50 mg/mL) completely at 37 C, pH 11, and with lactose and NH4H2PO4 used as carbon and nitrogen sources. Carbon 321-327 steroid sulfatase Homo sapiens 21-25 11238897-2 2001 The transcription of IME1 is repressed in the presence of glucose, and a low basal level of IME1 RNA is observed in vegetative cultures with acetate as the sole carbon source. Carbon 161-167 transcription factor IME1 Saccharomyces cerevisiae S288C 21-25 30914380-9 2019 Supported by the synergetic function of phosphoenolpyruvate carboxylase and Vitreoscilla hemoglobin encoded by genes ppc and vgb inserted into the chromosome of H. bluephagenesis TY194 (DeltasdhE) serving to enhance TCA cycle activity, a series of strains were generated that could produce PHBV containing 3-18mol% 3HV using glucose as a sole carbon source. Carbon 343-349 phosphoenolpyruvate carboxykinase 1 Homo sapiens 40-71 31289697-6 2019 Relating carbon economic efficiency to market values (US$) of agricultural products, indicated that the carbon economic efficiency (US$/kg CO2-eq) of the IFLP system was significantly greater than that of other systems (P < 0.01). Carbon 104-110 complement C2 Homo sapiens 139-142 32325561-3 2020 The dissolved organic carbon (DOC) extracted from the hydrochar and biochar ranged from 3.34-11.96% and 0.38-0.48%, respectively, and the highest DOM was released by HCK0.5 (180 C and 0.5% KOH). Carbon 22-28 HCK proto-oncogene, Src family tyrosine kinase Sus scrofa 166-169 32058034-0 2020 The role of the C-terminal domain of PCSK9 and SEC24 isoforms in PCSK9 secretion. Carbon 16-17 proprotein convertase subtilisin/kexin type 9 Homo sapiens 37-42 32058034-0 2020 The role of the C-terminal domain of PCSK9 and SEC24 isoforms in PCSK9 secretion. Carbon 16-17 proprotein convertase subtilisin/kexin type 9 Homo sapiens 65-70 32058034-2 2020 Previous studies have revealed the role of the C-terminal domain (CTD) of PCSK9 in its secretion, however, how CTD regulates PCSK9 secretion is not completely understood. Carbon 47-48 proprotein convertase subtilisin/kexin type 9 Homo sapiens 74-79 11238897-2 2001 The transcription of IME1 is repressed in the presence of glucose, and a low basal level of IME1 RNA is observed in vegetative cultures with acetate as the sole carbon source. Carbon 161-167 transcription factor IME1 Saccharomyces cerevisiae S288C 92-96 11162492-7 2001 Our results allow us to define Mig1p as a new factor probably contributing to the carbon source-dependent transcription regulation of HXK2 gene. Carbon 82-88 hexokinase 2 Homo sapiens 134-138 32589615-7 2020 The correlation and multiple linear regression analysis suggest that organic carbon sorption coefficient (Log Koc), octanol-water distribution coefficient (Log Dow), and molecular weight form a good predictive linear regression model for the removal efficiency of PhCs (R2 = 0.65, P-value <0.05). Carbon 77-83 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 110-113 32040076-2 2020 Full-length 7-transmembrane (TM) variants of MOR share similar amino acid sequences of TM domains in rodents and humans; however, interspecies differences in N- and C-terminal amino acid sequences of MOR splice variants dramatically affect the downstream signaling. Carbon 165-166 opioid receptor mu 1 Homo sapiens 45-48 32040076-2 2020 Full-length 7-transmembrane (TM) variants of MOR share similar amino acid sequences of TM domains in rodents and humans; however, interspecies differences in N- and C-terminal amino acid sequences of MOR splice variants dramatically affect the downstream signaling. Carbon 165-166 opioid receptor mu 1 Homo sapiens 200-203 31036724-8 2019 The present study demonstrates the presence of complicated regulatory mechanisms of GDH mediated by multiple compounds to control the carbon-nitrogen balance in bacterial cells.IMPORTANCE GDH, which catalyzes the synthesis and degradation of glutamate using NAD(P)(H), is a widely distributed enzyme among all domains of life. Carbon 134-140 glutamate dehydrogenase 1 Homo sapiens 84-87 31036724-8 2019 The present study demonstrates the presence of complicated regulatory mechanisms of GDH mediated by multiple compounds to control the carbon-nitrogen balance in bacterial cells.IMPORTANCE GDH, which catalyzes the synthesis and degradation of glutamate using NAD(P)(H), is a widely distributed enzyme among all domains of life. Carbon 134-140 glutamate dehydrogenase 1 Homo sapiens 188-191 31036724-13 2019 This suggests that T. thermophilus possesses a complicated regulatory mechanism of GDH to control carbon and nitrogen metabolism. Carbon 98-104 glutamate dehydrogenase 1 Homo sapiens 83-86 31120730-2 2019 In this study, a new organic-cadmium (Cd) complex formed through Cd2+ coordination with p-phenylenediamine (PPD) was used to synthesize highly active Fe-embedded N-doped carbon catalysts for the first time. Carbon 170-176 CD2 molecule Homo sapiens 65-68 32239160-4 2020 Simultaneously, compared with X-ray radiation, carbon ion radiation induced a marked increase in Bax and prominent decreases in cyclin B1 and Bcl-2 in a dose-dependent manner. Carbon 47-53 cyclin B1 Homo sapiens 128-137 31195953-0 2019 CircRNA-9119 suppresses poly I:C induced inflammation in Leydig and Sertoli cells via TLR3 and RIG-I signal pathways. Carbon 0-1 toll-like receptor 3 Mus musculus 86-90 11142398-0 2000 Carbon source-dependent transcriptional regulation of the mitochondrial glycerol-3-phosphate dehydrogenase gene, GUT2, from Saccharomyces cerevisiae. Carbon 0-6 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 72-106 31246570-3 2019 Also, the sum of atomic orbital spin populations on the carbon atoms in the skeleton of radicals ( s(C) Sigma AOSPRad), calculated with the semi-empirical parameterisation method 6 (PM6) in water, was used to correlate both Ep1 and AA, yielding R2=0.926 and 0.950, respectively. Carbon 56-62 prostaglandin E receptor 1 Homo sapiens 224-227 31245549-0 2019 A Carbon-Fiber Sheet Resistor for MR-, CT-, SPECT-, and PET-Compatible Temperature Maintenance in Small Animals. Carbon 2-8 nuclear receptor subfamily 3, group C, member 2 Mus musculus 34-36 32239160-5 2020 Furthermore, the Akt/mTOR/p70S6K pathway was significantly inhibited by carbon ion radiation in both breast cancer cell lines. Carbon 72-78 ribosomal protein S6 kinase B1 Homo sapiens 26-32 32239160-6 2020 These results indicate that carbon ion radiation kills MDA-MB-231 and MCF-7 breast cancer cells more effectively than X-ray radiation, which might result from the inhibition of the Akt/mTOR/p70S6K pathway. Carbon 28-34 ribosomal protein S6 kinase B1 Homo sapiens 190-196 32245759-4 2020 Fluorescence-labeled RAD23 was shown to normally localize in the cytoplasm, to migrate to vacuoles in the absence of carbon, nitrogen, or both, and to enter nuclei under various stresses, which include UVB, a harmful wavelength of sunlight. Carbon 117-123 Rad23p Saccharomyces cerevisiae S288C 21-26 11142398-0 2000 Carbon source-dependent transcriptional regulation of the mitochondrial glycerol-3-phosphate dehydrogenase gene, GUT2, from Saccharomyces cerevisiae. Carbon 0-6 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 113-117 11142398-2 2000 Transcriptional analysis of the GUT2 gene showed that it was repressed by glucose and derepressed on the non-fermentable carbon sources, glycerol, lactate and ethanol. Carbon 121-127 glycerol-3-phosphate dehydrogenase Saccharomyces cerevisiae S288C 32-36 11237093-3 2000 We report here the synthesis and study of the new unsymmetrical azo compounds SA-1, SA-2, C-16, C-12, and C-8 that decompose over a range of convenient temperatures and improve radical generation efficiency and access to lipid compartments. Carbon 90-91 stromal antigen 2 Homo sapiens 84-88 31033275-0 2019 Three-Dimensional CdS@Carbon Fiber Networks: Innovative Synthesis and Application as a General Platform for Photoelectrochemical Bioanalysis. Carbon 22-28 CDP-diacylglycerol synthase 1 Homo sapiens 18-21 31033275-1 2019 This Letter reports a novel synthetic methodology for the fabrication of three-dimensional (3D) nanostructured CdS@carbon fiber (CF) networks and the validation of its feasibility for applications as a general platform for photoelectrochemical (PEC) bioanalysis. Carbon 115-121 CDP-diacylglycerol synthase 1 Homo sapiens 111-114 32307492-0 2020 Osteopromotive carbon dots promote bone regeneration through the PERK-eIF2alpha-ATF4 pathway. Carbon 15-21 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 65-69 11237093-3 2000 We report here the synthesis and study of the new unsymmetrical azo compounds SA-1, SA-2, C-16, C-12, and C-8 that decompose over a range of convenient temperatures and improve radical generation efficiency and access to lipid compartments. Carbon 90-91 homeobox C8 Homo sapiens 106-109 11082060-2 2000 Being derived from a sugar containing only four carbons, TNA is structurally the simplest of all potentially natural oligonucleotide-type nucleic acid alternatives studied thus far. Carbon 48-55 C-type lectin domain family 3 member B Homo sapiens 57-60 32415123-0 2020 Synergy between the anthocyanin and RDR6/SGS3/DCL4 siRNA pathways expose hidden features of Arabidopsis carbon metabolism. Carbon 104-110 RNA-dependent RNA polymerase 6 Arabidopsis thaliana 36-40 32415123-0 2020 Synergy between the anthocyanin and RDR6/SGS3/DCL4 siRNA pathways expose hidden features of Arabidopsis carbon metabolism. Carbon 104-110 XS domain-containing protein / XS zinc finger domain-containing protein-like protein Arabidopsis thaliana 41-45 32415123-4 2020 We show that mutations in RDR6, SGS3, or DCL4 suppress the anthocyanin defect of tt19 by pushing carbon towards flavonoid biosynthesis. Carbon 97-103 RNA-dependent RNA polymerase 6 Arabidopsis thaliana 26-30 32415123-4 2020 We show that mutations in RDR6, SGS3, or DCL4 suppress the anthocyanin defect of tt19 by pushing carbon towards flavonoid biosynthesis. Carbon 97-103 XS domain-containing protein / XS zinc finger domain-containing protein-like protein Arabidopsis thaliana 32-36 31236115-8 2019 Our findings show that oxygen drives metabolite flux and specifies carbon fate in hPSC and, although the mechanism remains to be elucidated, oxygen was shown to alter methyltransferase and demethylase activity and the global epigenetic landscape. Carbon 67-73 methyl-CpG binding domain protein 2 Homo sapiens 189-200 11031029-3 2000 The synthetic strategy for the construction of the tetracyclic carbon framework was based on a C-->ABC-->ABCD ring annulation sequence, involving an aldol reaction, an intramolecular Diels-Alder reaction, and an intramolecular acylation as the key steps. Carbon 63-69 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 102-105 30912238-1 2019 B(npy)Ar2 (npy=2-(naphthalen-1-yl)pyridine) compounds bearing various nonbulky aryl groups undergo a clean and sequential two-step photoisomerization in which two aryl substituents on boron migrate to a carbon atom of the naphthyl moiety. Carbon 203-209 neuropeptide Y Homo sapiens 2-5 30912238-1 2019 B(npy)Ar2 (npy=2-(naphthalen-1-yl)pyridine) compounds bearing various nonbulky aryl groups undergo a clean and sequential two-step photoisomerization in which two aryl substituents on boron migrate to a carbon atom of the naphthyl moiety. Carbon 203-209 neuropeptide Y Homo sapiens 11-14 31845358-5 2020 In this work, we have obtained preparations of prohormone, half-cleaved rAMH and C-terminal fragment of rAMH, which was confirmed by qualitative and quantitative analyses. Carbon 81-82 anti-Mullerian hormone Rattus norvegicus 104-108 11465080-2 2000 The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (aglycone) at a nucleophilic functional group of oxygen (eg, hydroxyl or carboxylic acid groups), nitrogen (eg, amines), sulfur (eg, thiols), and carbon, with the formation of a beta-D-glucuronide product. Carbon 289-295 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 4-31 32152231-4 2020 Tissues from mice lacking ADTRP (Adtrp-KO), or both AIG1 and ADTRP (DKO) had higher concentrations of FAHFAs particularly isomers with the ester bond at the 9th carbon due to decreased FAHFA hydrolysis activity. Carbon 161-167 androgen dependent TFPI regulating protein Mus musculus 33-41 32204042-12 2020 It revealed that the pro-inflammatory cytokines (TNF-alpha and IL-1beta) were significantly upregulated on PCL nanofibers, while their expression was comparatively lower on poly-l-lysine coated PCL or PVP-I/PCL(c/s) nanofibers. Carbon 38-39 interleukin 1 alpha Mus musculus 63-71 30809670-2 2019 Human serine hydroxymethyltransferase (SHMT) is essential for the one-carbon metabolism, which sustains growth and proliferation in normal and tumour cells. Carbon 70-76 serine hydroxymethyltransferase 1 Homo sapiens 6-37 30809670-2 2019 Human serine hydroxymethyltransferase (SHMT) is essential for the one-carbon metabolism, which sustains growth and proliferation in normal and tumour cells. Carbon 70-76 serine hydroxymethyltransferase 1 Homo sapiens 39-43 11465080-2 2000 The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (aglycone) at a nucleophilic functional group of oxygen (eg, hydroxyl or carboxylic acid groups), nitrogen (eg, amines), sulfur (eg, thiols), and carbon, with the formation of a beta-D-glucuronide product. Carbon 289-295 UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens 33-36 30924601-0 2019 Carbon-Coated and Interfacial-Functionalized Mixed-Phase Mox Ti1-x O2-delta Nanotubes as Highly Active and Durable PtRu Catalyst Support for Methanol Electrooxidation. Carbon 0-6 monooxygenase DBH like 1 Homo sapiens 57-60 31859331-0 2020 Platinum ions mediate the interactions between DNA and carbon quantum dots: diagnosis of MRSA infections. Carbon 55-61 solute carrier family 9 member A6 Homo sapiens 89-93 31859331-1 2020 In this study, we have developed a rapid and cost-effective method employing platinum ion (Pt4+)-capped fluorescent carbon quantum dots (CQDs) coupled with loop-mediated isothermal amplification (LAMP) to detect dual MRSA genes. Carbon 116-122 solute carrier family 9 member A6 Homo sapiens 217-221 10956023-2 2000 We describe a new isomerization, that of L-2-hydroxyglutarate to L-threo-3-methylmalate, involving the migration of the carbinol carbon. Carbon 129-135 immunoglobulin kappa variable 3-15 Homo sapiens 41-44 29962328-0 2019 Effects of single-walled carbon nanotube on the conformation of human hepcidin: molecular dynamics simulation and binding free energy calculations. Carbon 25-31 hepcidin antimicrobial peptide Homo sapiens 70-78 10910691-2 2000 A high-resolution 3D CSA-CSA-CSA correlation experiment based on the magic angle turning technique is reported in which the conventional 90 degrees 2D CSA-CSA powder pattern for each carbon in a system containing a number of inequivalent carbons may be separated according to the isotropic chemical shift value. Carbon 183-189 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 21-24 31019232-4 2019 Here we show that in addition to the well-characterized glucose (and galactose) repression of ADH2 (alcohol dehydrogenase 2, required for efficient utilization of ethanol as a carbon source), ADH2 expression is also inhibited by acetate which is produced during ethanol catabolism. Carbon 176-182 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 94-98 31019232-4 2019 Here we show that in addition to the well-characterized glucose (and galactose) repression of ADH2 (alcohol dehydrogenase 2, required for efficient utilization of ethanol as a carbon source), ADH2 expression is also inhibited by acetate which is produced during ethanol catabolism. Carbon 176-182 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 192-196 32255129-0 2019 Amorphous carbon modification on implant surface: a general strategy to enhance osteogenic differentiation for diverse biomaterials via FAK/ERK1/2 signaling pathways. Carbon 10-16 protein tyrosine kinase 2 Rattus norvegicus 136-139 32255129-6 2019 Furthermore, it was demonstrated that the FAK/ERK1/2 signaling pathways were involved in the osteogenic effects of this amorphous carbon coating. Carbon 130-136 protein tyrosine kinase 2 Rattus norvegicus 42-45 32391500-0 2020 Tripeptide Derivative-Modified Glassy Carbon Electrode: A Novel Electrochemical Sensor for Sensitive and Selective Detection of Cd2+ Ions. Carbon 38-44 CD2 molecule Homo sapiens 128-131 31848092-2 2020 Alumina membrane was submerged directly into a fluidized membrane reactor specially designed for fluidizing the granular activated carbon (GAC) particles along membrane surface by recirculating a bulk wastewater through the reactor to improve fouling control and removal efficiency of contaminants. Carbon 131-137 glutaminase Homo sapiens 139-142 32296963-0 2020 Co/CoP Nanoparticles Encapsulated Within N, P-Doped Carbon Nanotubes on Nanoporous Metal-Organic Framework Nanosheets for Oxygen Reduction and Oxygen Evolution Reactions. Carbon 52-58 caspase recruitment domain family member 16 Homo sapiens 3-6 32296963-1 2020 Herein, Co/CoP nanoparticles encapsulated with N, P-doped carbon nanotubes derived from the atomic layer deposited hexagonal metal-organic frameworks (MOFs) are obtained by calcinations and subsequent phosphating and are employed as electrocatalyst. Carbon 58-64 caspase recruitment domain family member 16 Homo sapiens 11-14 10910691-2 2000 A high-resolution 3D CSA-CSA-CSA correlation experiment based on the magic angle turning technique is reported in which the conventional 90 degrees 2D CSA-CSA powder pattern for each carbon in a system containing a number of inequivalent carbons may be separated according to the isotropic chemical shift value. Carbon 238-245 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 21-24 30475616-2 2019 This novel route features several remarkably diastereoselective and high-yielding transformations, including construction of the all-carbon quaternary stereogenic center at C-2 via a thermodynamic aldol reaction. Carbon 133-139 complement C2 Homo sapiens 173-176 10923842-3 2000 The APCI spectra of alkaloids were predominantly the [M+H]+ ion and the major fragment ion, corresponding to the [M+H-H2O]+ ion or the [M+H-CH3COOH]+ ion, and comparison of the APCI spectra showed that the abundance of fragment ions was significantly higher for C-1 beta-form alkaloids than for C-1 alpha-form alkaloids, and for C-12 beta-form alkaloids than for C-12 alpha-form alkaloids. Carbon 6-7 endogenous retrovirus group K member 1 Homo sapiens 295-304 30640085-8 2019 The MWHIX also presented a good positive correlation with pyrene organic carbon-normalized binding coefficients (Koc). Carbon 73-79 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 113-116 30639911-5 2019 To further investigate the source of spectral features, the spectral components calculated from different types of carbon atoms in each C32 isomer also have been well explored and discussed. Carbon 115-121 chemokine like factor Homo sapiens 136-139 32019022-6 2020 Specifically, biochar properties including pH, cation exchange capacity (CEC), contents of carbon and ash, bulk density, and soil conditions including texture, pH, CEC, nitrogen content, and C/N ratio significantly affected the results of PPR to biochar addition. Carbon 91-97 PPR1 Homo sapiens 239-242 19002834-3 2000 Analog of STL-3 witheven-number or odd-number carbon chain and unsaturatedfatty acids strongly inhibited growth and induced thedifferentiation of HL-60 cells, as evaluated in termsof nitroblue tetrazilium-reducing activity and theappearance of the CD36 antigen. Carbon 46-52 collagen type XI alpha 2 chain Homo sapiens 10-15 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 249-255 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 31-34 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 249-255 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 56-59 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 249-255 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 56-59 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 249-255 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 56-59 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 256-262 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 31-34 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 256-262 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 56-59 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 256-262 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 56-59 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 256-262 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 56-59 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 256-262 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 31-34 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 256-262 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 56-59 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 256-262 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 56-59 30803063-3 2019 The as-prepared single atoms, supported by N-doped carbon flake arrays grown on carbon nanofibers assembly (M SA@NCF/CNF), demonstrate the dual characteristics of excellent catalytic activity (reversible oxygen overpotential of 0.75 V) and high stability, owing to the greatly improved active sites" accessibility and optimized single-sites/pore-structures correlations. Carbon 51-57 neutrophil cytosolic factor 4 Homo sapiens 113-116 30803063-3 2019 The as-prepared single atoms, supported by N-doped carbon flake arrays grown on carbon nanofibers assembly (M SA@NCF/CNF), demonstrate the dual characteristics of excellent catalytic activity (reversible oxygen overpotential of 0.75 V) and high stability, owing to the greatly improved active sites" accessibility and optimized single-sites/pore-structures correlations. Carbon 80-86 neutrophil cytosolic factor 4 Homo sapiens 113-116 32627429-4 2019 Single-walled carbon nanotubes are introduced to neural stem cells at different stages of differentiation at concentrations as low as 5 ng mL-1 . Carbon 14-20 L1 cell adhesion molecule Mus musculus 139-143 30663099-2 2019 The aim of this study was to prepare a new derivative of 1-(2-methoxyphenyl)piperazine (MPP) as a main chemical structure of 5HT1A receptor antagonist with 3-carbon linker and radiolabeled by [99m Tc][Tc(CO)3 (H2 O)3 ]+ precursor. Carbon 158-164 5-hydroxytryptamine receptor 1A Homo sapiens 125-139 10873746-2 2000 In our previous studies, the proteinase was identified as a 33-kDa protein in IBV-infected cells, and its catalytic center was shown to consist of H(2820) and C(2922) residues. Carbon 159-160 endogenous retrovirus group K member 18 Homo sapiens 29-39 30903027-3 2019 Applied to study reductive glutamine metabolism in cancer cells, shown to mediate fatty acid biosynthesis under hypoxia and defective mitochondria, we find a previously unappreciated role of reductive IDH1 as the sole net contributor of carbons to fatty acid biosynthesis under standard normoxic conditions in HeLa cells. Carbon 237-244 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 201-205 30886181-0 2019 Dissolved organic carbon contribution to oxygen respiration in the central Red Sea. Carbon 18-24 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 79-82 32290330-2 2020 Here, the preparation of 1,1,1-tri(boryl)alkanes, 1,2,3-tri(boryl)alkanes, 1,1,2-tri(boryl)alkanes, as well as 1,1,2-tri(boryl)alkenes as suitable and accessible polyborated systems is demonstrated as being easily applied in the construction of new carbon-carbon and carbon-heteroatom bonds. Carbon 256-262 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 56-59 32014251-6 2020 We prepared a rabbit polyclonal antibody against the ES1 C-terminal and performed western blotting analysis and immunoelectron microscopy. Carbon 57-58 glutamine amidotransferase class 1 domain containing 3, like Danio rerio 53-56 10828986-3 2000 Determinations of chloroplast fructose-1,6-bisphosphatase and sedoheptulose-1,7-bisphosphatase activity showed that the light-dependent, reductive activation of these key carbon reduction cycle enzymes was substantially inhibited in tomato (Lycopersicon esculentum) following illumination at 4 degrees C. However, other chloroplast enzymes also dependent on thioredoxin-mediated reductive activation were largely unaffected. Carbon 171-177 thioredoxin-like protein CITRX, chloroplastic Solanum lycopersicum 358-369 32138914-2 2020 The prepared dual-emission carbon dots can be used for ratiometric detection of Fe3+ ions in the range from 0 to 50 mumol L-1 with 0.8 mumol L-1 detection limit based on the fluorescence quenching at 570 nm. Carbon 27-33 L1 cell adhesion molecule Mus musculus 122-125 32138914-2 2020 The prepared dual-emission carbon dots can be used for ratiometric detection of Fe3+ ions in the range from 0 to 50 mumol L-1 with 0.8 mumol L-1 detection limit based on the fluorescence quenching at 570 nm. Carbon 27-33 L1 cell adhesion molecule Mus musculus 141-144 32138914-4 2020 We further used the carbon dots-Fe3+ ions-pyrophosphate mixed system for ratiometric detection of acid phosphatase in the range from 0.08 to 6.75 mug mL-1 with 0.01 mug mL-1 detection limit. Carbon 20-26 L1 cell adhesion molecule Mus musculus 150-154 30686752-7 2019 Docking simulations also implied that 6 interacted with hMAO-A at Phe208 and with hMAO-B at Ile199 by carbon hydrogen bondings. Carbon 102-108 monoamine oxidase A Homo sapiens 56-62 10816546-3 2000 Here, evidence is presented that the mutation in SR-11 Fad(-) that renders the strain avirulent is in the cra gene, which encodes the Cra protein, a regulator of central carbon metabolism. Carbon 170-176 myotubularin related protein 11 Mus musculus 106-109 30530023-5 2019 The hybrids were further modified by carbon nanodots (CDots) ({101}TiO2/CdS/CDots) to enhance photocatalytic performance (99.84%). Carbon 37-43 CDP-diacylglycerol synthase 1 Homo sapiens 72-75 30724552-2 2019 Due to its role in one carbon metabolism, chromosomal DHFR is the target of the antibacterial drug, trimethoprim. Carbon 23-29 Dihydrofolate reductase Escherichia coli 54-58 32138914-4 2020 We further used the carbon dots-Fe3+ ions-pyrophosphate mixed system for ratiometric detection of acid phosphatase in the range from 0.08 to 6.75 mug mL-1 with 0.01 mug mL-1 detection limit. Carbon 20-26 L1 cell adhesion molecule Mus musculus 169-173 32309747-0 2020 Red-Emitting Carbon Dots as a Dual Sensor for In3+ and Pd2+ in Water. Carbon 13-19 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 55-58 32309747-1 2020 We have demonstrated the synthesis, characterization, and application of nitrogen-doped red-emitting carbon dots (NRCDs) for dual sensing of indium (In3+) and palladium (Pd2+) in water. Carbon 101-107 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 170-173 30661461-9 2019 Receiver operating characteristic curves showed that several biomarkers can serve as robust pollutant-specific predictors with high versus low black carbon exposure (area under the receiver operating characteristic curve of 0.974 [95% CI, 0.955-0.992] for MMP-8 and 0.962 [95% CI, 0.935-0.988] for sRAGE). Carbon 149-155 matrix metallopeptidase 8 Homo sapiens 256-261 10816546-3 2000 Here, evidence is presented that the mutation in SR-11 Fad(-) that renders the strain avirulent is in the cra gene, which encodes the Cra protein, a regulator of central carbon metabolism. Carbon 170-176 myotubularin related protein 11 Mus musculus 134-137 30476532-4 2019 Non-cytotoxic doses of carbon nanoparticles but not of bigger carbon particles led to an irreversible reduction of the proliferative capacity accompanied by the accumulation of the cell cycle blocking proteins p21 and p16 as well as a loss of both redox sensitive histone deacetylase SIRT1 and connexin-43. Carbon 23-29 H3 histone pseudogene 16 Homo sapiens 210-213 10748136-6 2000 Cells in which Isa1p was depleted by regulated gene expression maintained the mitochondrial DNA, yet the cells displayed retarded growth on nonfermentable carbon sources. Carbon 155-161 Fe-binding Fe/S cluster assembly protein ISA1 Saccharomyces cerevisiae S288C 15-20 30609543-2 2019 In this work, a simple and reproducible SERS substrate combining the properties of multi-walled carbon nanotubes (MWCNTs) and gold nanoparticles (AuNPs), is proposed for the determination and quantification of sulfapyridine in milk samples with a concentration range of 10-100 ng mL-1. Carbon 96-102 L1 cell adhesion molecule Mus musculus 280-284 32328942-0 2020 Combined Administration of TLR4 (LPS) and TLR3 (Poly I:C) Ligands to CBA Mice Elevates the Content of Osteogenic MSC by 1.6 Times and Increases Content of Bone Marrow MSC to Intermediate Level between Values Attained by Their Individual Administration. Carbon 0-1 toll-like receptor 3 Mus musculus 42-46 32328942-1 2020 In 1 and 24 h after combined administration of TLR4 (LPS) and TLR3 (Poly I:C) ligands to CBA mice, the content of MSC in bone marrow increased to intermediate value between the levels attained by their individual injections. Carbon 75-76 toll-like receptor 3 Mus musculus 62-66 32273347-6 2020 RESULTS: In vitro-generated CD103+ cDC1s produced cDC1-associated factors such as interleukin-12p70 and CXCL10, and demonstrated antigen cross-presentation activity on stimulation with the toll-like receptor 3 agonist polyinosinic:polycytidylic acid (poly I:C). Carbon 28-29 toll-like receptor 3 Mus musculus 189-209 30694296-0 2019 A flexible CdS nanorods-carbon nanotubes/stainless steel mesh photoanode for boosted photoelectrocatalytic hydrogen evolution. Carbon 24-30 CDP-diacylglycerol synthase 1 Homo sapiens 11-14 10799481-1 2000 Cu(2+) and Zn(2+) inhibit all of the NADPH-dependent reactions catalyzed by neuronal nitric-oxide synthase (nNOS) including ferricytochrome c reduction, NADPH oxidation, and citrulline formation. Carbon 56-57 nitric oxide synthase 1 Homo sapiens 76-106 30600818-0 2019 Role of ILK/p38 pathway in mediating the enhanced osteogenic differentiation of bone marrow mesenchymal stem cells on amorphous carbon coating. Carbon 128-134 integrin-linked kinase Rattus norvegicus 8-11 30600818-12 2019 Above all, our study indicates that the a-C coating is able to promote osteogenic differentiation of MSCs through the ILK/p38 signaling pathway. Carbon 42-43 integrin-linked kinase Rattus norvegicus 118-121 32244825-0 2020 Ultrasonic Welding of Novel Carbon/ Elium Thermoplastic Composites with Flat and Integrated Energy Directors: Lap Shear Characterisation and Fractographic Investigation. Carbon 28-34 LAP Homo sapiens 111-114 32694609-2 2020 Here, we identify the compensatory mechanisms following the inhibition of major pathways of central carbon metabolism in c-MYC-induced liver tumours. Carbon 100-106 MYC proto-oncogene, bHLH transcription factor Homo sapiens 121-126 10799481-1 2000 Cu(2+) and Zn(2+) inhibit all of the NADPH-dependent reactions catalyzed by neuronal nitric-oxide synthase (nNOS) including ferricytochrome c reduction, NADPH oxidation, and citrulline formation. Carbon 56-57 nitric oxide synthase 1 Homo sapiens 108-112 10799481-5 2000 However, Cu(2+) inhibits ferricytochrome c reduction by the full-length nNOS 2 orders of magnitude more potently, with an estimated IC(50) value of 0.12 microm. Carbon 30-31 nitric oxide synthase 1 Homo sapiens 72-76 31987217-0 2020 Enzyme-free sandwich-type electrochemical immunosensor for highly sensitive prostate specific antigen based on conjugation of quantum dots and antibody on surface of modified glassy carbon electrode with core-shell magnetic metal-organic frameworks. Carbon 182-188 kallikrein related peptidase 3 Homo sapiens 76-101 30834327-8 2019 PYK2 is expressed during respiration and proves advantageous for growth on three-carbon substrates. Carbon 81-87 pyruvate kinase PYK2 Saccharomyces cerevisiae S288C 0-4 10779621-6 2000 Strains degrading naphthalene, a simple PAH, did exist in the soil inocula used, but could be isolated only when enrichments were performed using pure naphthalene as the sole carbon source. Carbon 175-181 phenylalanine hydroxylase Homo sapiens 40-43 30736465-1 2019 The strongly fluorescent and highly catalytic N-doped carbon dots (CDN) were rapidly prepared by a microwave irradiation procedure and were characterized by electron microscopy (EM), laser scattering, infrared spectroscopy (IR), and by their fluorescence spectrum. Carbon 54-60 5', 3'-nucleotidase, cytosolic Homo sapiens 67-70 31830361-4 2020 NMR spectroscopy shows that CypA catalyzes isomerization of proline 128 in alpha -synuclein"s C-terminal domain. Carbon 28-29 synuclein alpha Homo sapiens 76-92 32024695-0 2020 The glutamic acid-rich long C-terminal extension of troponin T has a critical role in insect muscle functions. Carbon 28-29 upheld Drosophila melanogaster 52-62 32024695-5 2020 TnT in insects contains a highly diverged structure consisting of a long glutamic acid-rich C-terminal extension of ~70 residues with unknown function. Carbon 92-93 upheld Drosophila melanogaster 0-3 32024695-6 2020 We found here that C-terminally truncated Drosophila TnT (TpnT-CD70) retains binding of tropomyosin, troponin I, and troponin C, indicating a preserved core structure of TnT. Carbon 19-20 upheld Drosophila melanogaster 53-56 32024695-6 2020 We found here that C-terminally truncated Drosophila TnT (TpnT-CD70) retains binding of tropomyosin, troponin I, and troponin C, indicating a preserved core structure of TnT. Carbon 19-20 upheld Drosophila melanogaster 58-67 32024695-6 2020 We found here that C-terminally truncated Drosophila TnT (TpnT-CD70) retains binding of tropomyosin, troponin I, and troponin C, indicating a preserved core structure of TnT. Carbon 19-20 Tropomyosin 1 Drosophila melanogaster 88-99 32024695-6 2020 We found here that C-terminally truncated Drosophila TnT (TpnT-CD70) retains binding of tropomyosin, troponin I, and troponin C, indicating a preserved core structure of TnT. Carbon 19-20 upheld Drosophila melanogaster 170-173 30906627-10 2019 Upregulation of miR-940 expression inhibited the expression of MTHFD2 and led to intracellular one-carbon metabolism dysfunction. Carbon 99-105 microRNA 940 Homo sapiens 16-23 10720584-1 2000 An adenine/cytosine (A/C) base substitution at position 1166 in the angiotensin II type 1 receptor (AT(1)R) gene is associated with the incidence of essential hypertension and increased coronary artery vasoconstriction. Carbon 23-24 angiotensin II receptor type 1 Homo sapiens 68-98 30182341-8 2019 RESULTS: We found that the combination of poly(I:C) and cisplatin downregulated c-IAP2 and survivin expression, reduced cell survival, induced anti-apoptotic gene expression and apoptosis, increased ROS formation and induced G2/M cell cycle arrest in the HNSCC-derived cells tested. Carbon 49-50 baculoviral IAP repeat containing 3 Homo sapiens 80-86 32024695-12 2020 Our findings suggest that the Glu-rich long C-terminal extension of insect TnT functions as a myofilament Ca2+buffer/reservoir, potentially critical to the high-frequency asynchronous contraction of flight muscles. Carbon 44-45 upheld Drosophila melanogaster 75-78 32017918-4 2020 Nuclear magnetic resonance analysis reveals that SEW84 binds to the C-terminal domain of Aha1 to weaken its asymmetric binding to Hsp90. Carbon 68-69 heat shock protein 90 alpha family class A member 1 Homo sapiens 130-135 32108462-7 2020 The main carbon-based photoreduction product of CdS/A-GO is CH3OH, whereas that of CdS/GO and CdS/P-GO is CO. Carbon 9-15 CDP-diacylglycerol synthase 1 Homo sapiens 48-51 30442673-9 2019 Of these, an analog in which the EFV alkyne is replaced with an alkene and an analog in which the oxazinone oxygen is replaced by a carbon stimulated XBP1 splicing in human, mouse, and macaque hepatocytes. Carbon 132-138 X-box binding protein 1 Homo sapiens 150-154 10720584-1 2000 An adenine/cytosine (A/C) base substitution at position 1166 in the angiotensin II type 1 receptor (AT(1)R) gene is associated with the incidence of essential hypertension and increased coronary artery vasoconstriction. Carbon 23-24 angiotensin II receptor type 1 Homo sapiens 100-106 32313843-0 2019 Multi-walled carbon nanotubes inhibit estrogen receptor expression in vivo and in vitro through transforming growth factor beta1. Carbon 13-19 estrogen receptor 1 (alpha) Mus musculus 38-55 10677442-4 2000 Plants with reduced glyceraldehyde 3-phosphate dehydrogenase (anti-GAPDH) have a decreased capacity to use ATP and NADPH in carbon assimilation. Carbon 124-130 glyceraldehyde-3-phosphate dehydrogenase, cytosolic Nicotiana tabacum 20-60 31459457-2 2019 Here, a series of nitrogen-doped (N-doped) activated carbon catalysts (N-AC) were prepared conveniently for EDC dehydrochlorination. Carbon 53-59 synuclein alpha Homo sapiens 71-75 32254727-3 2019 Manganese phosphate is a typical Nanozyme used in this design and the shape and size of the Mnx(PO4)y layer can be efficiently controlled by altering the carbon substrates. Carbon 154-160 keratin 86 Homo sapiens 92-95 32254727-4 2019 Characterization demonstrated that Mnx(PO4)y layer modified hollow carbon sphere (Mn-MPSA-HCS) and hollow carbon cubic (Mn-MPSA-HCC) were successfully prepared and used as nanozymes for superoxide detection. Carbon 67-73 keratin 86 Homo sapiens 35-38 32009148-3 2020 Although we previously defined the catalytic machinery controlling Class 2 nuclease cleavage, degenerate conservation of the C-termini between classes precludes pinpointing the analogous residues in Class 1 enzymes by sequence alignment alone. Carbon 67-68 nuclease Escherichia coli 75-83 32009148-5 2020 Here we present the full-length structure of the Class 1 OLD nuclease from Thermus scotoductus (Ts) at 2.20 A resolution, which reveals a dimerization domain inserted into an N-terminal ABC ATPase fold and a C-terminal Toprim domain. Carbon 49-50 nuclease Escherichia coli 61-69 10758479-0 2000 Dof1 and Dof2 transcription factors are associated with expression of multiple genes involved in carbon metabolism in maize. Carbon 97-103 DNA-binding protein MNB1 Zea mays 0-4 32123097-0 2020 Carbon export from leaves is controlled via ubiquitination and phosphorylation of sucrose transporter SUC2. Carbon 0-6 sucrose transporter 2 Arabidopsis thaliana 102-106 32123097-3 2020 In the model plant Arabidopsis thaliana, transport of sucrose into the phloem vascular tissue by SUCROSE TRANSPORTER 2 (SUC2) sets the rate of carbon export from source leaves, just like the SUC2 homologs of most crop plants. Carbon 143-149 sucrose transporter 2 Arabidopsis thaliana 97-118 32123097-3 2020 In the model plant Arabidopsis thaliana, transport of sucrose into the phloem vascular tissue by SUCROSE TRANSPORTER 2 (SUC2) sets the rate of carbon export from source leaves, just like the SUC2 homologs of most crop plants. Carbon 143-149 sucrose transporter 2 Arabidopsis thaliana 120-124 32218789-9 2020 IC87114 also attenuated poly I:C-induced increases in numbers of total cells, macrophages, neutrophils and lymphocytes, as well as levels of KC, IL-6 and MIP-1beta in bronchoalveolar lavage fluid. Carbon 1-2 C-C motif chemokine ligand 3 Homo sapiens 154-163 30746462-4 2019 Using an enhanced atomic intermixing approach, we develop a ~7- to 8-nm-thick carbon/silicon nitride (C/SiN x ) multilayer overcoat demonstrating extremely high wear resistance and low friction at all tribological length scales, yielding ~2 to 10 times better macroscale wear durability than previously reported thicker (~20 to 100 nm) overcoats on tape drive heads. Carbon 78-84 embryonal Fyn-associated substrate Homo sapiens 104-107 32218789-13 2020 IC87114 decreased poly I:C-induced PD-L1 expression on PBECs and secretion of IL-6 and IL-8 into culture supernatants. Carbon 1-2 CD274 molecule Homo sapiens 35-40 10628872-0 1999 Cat8p, the activator of gluconeogenic genes in Saccharomyces cerevisiae, regulates carbon source-dependent expression of NADP-dependent cytosolic isocitrate dehydrogenase (Idp2p) and lactate permease (Jen1p). Carbon 83-89 isocitrate dehydrogenase (NADP(+)) IDP2 Saccharomyces cerevisiae S288C 172-177 30569925-2 2019 Herein, a novel, multidimensional and hierarchical nanostructure is synthesized which constitutes 0D CoP nanoparticles distrbuted in a 1D dual carbon matrix and further homogenously encapsulated in a 3D graphene (GR) network; this material is denoted as CoP@DC@GR. Carbon 143-149 caspase recruitment domain family member 16 Homo sapiens 101-104 10628872-1 1999 The yeast transcriptional activator Cat8p has been identified as a factor that is essential for the derepression of genes involved in gluconeogenesis (like FBP1, PCK1, ACR1, ICL1 and MLS1) when only nonfermentable carbon sources are provided. Carbon 214-220 fructose 1,6-bisphosphate 1-phosphatase Saccharomyces cerevisiae S288C 156-160 32184496-1 2020 The effectiveness of granular activated carbon (GAC) for carcinogenic volatile organic compounds (cVOCs) has not been evaluated in the low- to sub- microgram per liter range. Carbon 40-46 glutaminase Homo sapiens 48-51 30617429-10 2019 Graphical abstract Schematic of the hydrothermal method for synthesis of carbon and nickel oxide nanoparticle composites (GCD/NiO-150, GCD/NiO-300, and GCD/NiO-450). Carbon 73-79 guanylate cyclase 2E, pseudogene Homo sapiens 122-125 10557229-5 1999 The introduction of the N-terminal kinase region of WPK4 into the yeast snf1 mutant cells, which cannot utilize Suc as a carbon source, rescued growth in Suc-containing medium. Carbon 121-127 CBL-interacting protein kinase 19 Triticum aestivum 52-56 31459327-2 2019 Here, MP2 calculations with aug-cc-pVDZ basis set (aug-cc-pVDZ-pp for element Sn) were used to optimize the geometric configurations of the hydrogen-bonded complexes MH3F HCN (M = C, Si, Ge, and Sn), carbon-bonded complexes HCN MH3F (M = C, Si, Ge, and Sn), and transition states; the conversion mechanism between these two types of interactions has been carried out. Carbon 202-208 tryptase pseudogene 1 Homo sapiens 6-9 32184496-6 2020 The carbon use rate (CUR), when scaled to simulate full-scale adsorption, indicated that GAC would be a viable technology for seven of the VOCs evaluated, with a CUR threshold less than 0.2 lbs/1000 gal. Carbon 4-10 glutaminase Homo sapiens 89-92 31823504-9 2020 In the Abeta fly model, this correlates with high Abeta1-42 levels and down-regulation of the levels of mRNA encoding lysosomal associated membrane protein 1, lamp1 (a lysosomal marker), while in the AbetaPP-BACE1 fly model, neuronal cell death correlates with low Abeta1-42 levels, up-regulation of lamp1 mRNA levels and increased levels of C-terminal fragments (CTFs). Carbon 210-211 Lamp1 Drosophila melanogaster 159-164 31944406-2 2020 Intriguingly, our current knowledge is based solely on the role of S1P with an 18-carbon long-chain base length, S1P d18:1. Carbon 79-88 sphingosine-1-phosphate receptor 1 Mus musculus 67-70 31407615-1 2019 This article demonstrates the first application of a copper-based porous coordination polymer (BTCA-P-Cu-CP) as a carbon paste electrode (CPE) modifier for the detection of malathion. Carbon 114-120 carboxypeptidase E Homo sapiens 138-141 10421739-2 1999 These thermally, hydrothermally, and acid-base-treated carbons have been characterized using BET, thermogravimetric, and infrared techniques. Carbon 55-62 delta/notch like EGF repeat containing Homo sapiens 93-96 30059930-6 2019 The basic ingredients of the AD, such as vegetables and legumes, make a relatively minor contribution (with an impact of 30% of the total) to the total carbon footprint of 3.01 kg CO2eq person-1 day-1. Carbon 152-158 complement C2 Homo sapiens 180-183 10411265-2 1999 While prpE mutants used propionate as carbon and energy source, prpE mutants that lacked acetyl-CoA synthetase (encoded by acs) did not, indicating that Acs can compensate for the lack of PrpE in prpE mutants. Carbon 38-44 propionate--CoA ligase Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 6-10 30535660-2 2018 The sensor consists of a carbon paste electrode modified with nickel titanate nanoceramics (NiTiO3/CPE). Carbon 25-31 carboxypeptidase E Homo sapiens 92-102 30535660-8 2018 Then, a carbon paste electrode modified with NiTiO3 (NiTiO3/CPE) was constructed. Carbon 8-14 carboxypeptidase E Homo sapiens 53-63 30223076-0 2018 Facile marriage of Gd3+ to polymer-coated carbon nanodots with enhanced biocompatibility for targeted MR/fluorescence imaging of glioma. Carbon 42-48 GRDX Homo sapiens 19-22 31892044-3 2020 Here, a novel electrochemical biosensor for detection of miR-21 was demonstrated, through combining the advantages of electrochemical methods and nanomaterials with the selectivity of oligonucleotides, based on thiolated receptor probe-functionalized dendritic gold nanostructures (den-Au) via the self-assembly monolayer (SAM) process which grafted on the single-wall carbon nanotubes (SWCNTs) platform on the surface of the fluorine-doped tin oxide (FTO) electrode. Carbon 369-375 microRNA 21 Homo sapiens 57-63 32049494-0 2020 Fluorine Doped Cagelike Carbon Electrocatalyst: An Insight into the Structure-Enhanced CO Selectivity for CO2 Reduction at High Overpotential. Carbon 24-30 complement C2 Homo sapiens 106-109 32085439-15 2020 Consequently, SUMO3, ALC1, POLE4, PCBP4, MUTYH expression correlated with the higher RBE of carbon ions. Carbon 92-98 poly(rC) binding protein 4 Homo sapiens 34-39 10231886-1 1999 The purpose of this research was to construct an amperometric biosensor on L-amino acid oxidase (L-AAOD) supported on a carbon paste for the enantioselective analysis of S-cilazapril (I), S-trandolapril (II), and S-pentopril (III). Carbon 120-126 interleukin 4 induced 1 Homo sapiens 75-95 32072307-4 2020 As a sensing electrode for AA, 2-CuS NCs modified glassy carbon electrode (2-CuS NCs/GCE) exhibited eminent electrocatalytic activity in terms of satisfying sensitivity (523.7 muA mM-1 cm-2), short response time (0.31 s), and low limit of detection (LOD, 0.15 muM). Carbon 57-63 guanylate cyclase 2E, pseudogene Homo sapiens 85-88 30031257-1 2018 A new bimetallic Co/Fe-MOF was synthesized and phosphatized to produce a visible-light-active Co/Fe binary metal phosphide embedded in a mesoporous carbon matrix (denoted by CoP/Fe2P@mC). Carbon 148-154 caspase recruitment domain family member 16 Homo sapiens 174-177 30031257-3 2018 Combining the high electron-hole separation rate of Fe2P@mC, fast electron transfer of CoP@mC, and the strong adsorption of mesoporous carbon, the as-prepared CoP/Fe2P@mC catalyst exhibits substantially enhanced photocatalytic activity toward rhodamine B (RhB) degradation under visible light irradiation. Carbon 135-141 caspase recruitment domain family member 16 Homo sapiens 159-162 10048586-0 1999 Carbon source-dependent regulation of cell growth by murine protein kinase C epsilon expression in Saccharomyces cerevisiae. Carbon 0-6 protein kinase C, epsilon Mus musculus 60-84 30333150-9 2018 Since the multiple double and triple carbon-carbon bonds that distinguish polyacetylenes from ubiquitous fatty acids are often introduced by Delta12 oleic acid desaturase (FAD2)-type enzymes, we mined the carrot genome for FAD2 genes. Carbon 37-43 fatty acid desaturase 2 Arabidopsis thaliana 172-176 30333150-9 2018 Since the multiple double and triple carbon-carbon bonds that distinguish polyacetylenes from ubiquitous fatty acids are often introduced by Delta12 oleic acid desaturase (FAD2)-type enzymes, we mined the carrot genome for FAD2 genes. Carbon 44-50 fatty acid desaturase 2 Arabidopsis thaliana 172-176 30740289-3 2019 Upon modifying the ancillary ligands, or proceeding along the catalytic cycle, hapticity changes can be observed; it varies from eta5, if the five metal-carbon distances are identical, through eta3+eta2, in the presence of allylic distortion, and eta3, in the case of allylic coordination, to eta1, if a sigma metal-carbon bond forms. Carbon 153-159 secreted phosphoprotein 1 Homo sapiens 293-297 30740289-3 2019 Upon modifying the ancillary ligands, or proceeding along the catalytic cycle, hapticity changes can be observed; it varies from eta5, if the five metal-carbon distances are identical, through eta3+eta2, in the presence of allylic distortion, and eta3, in the case of allylic coordination, to eta1, if a sigma metal-carbon bond forms. Carbon 316-322 secreted phosphoprotein 1 Homo sapiens 293-297 30203428-0 2018 An Efficient Anti-poisoning Catalyst against SOx , NOx , and POx : P, N-Doped Carbon for Oxygen Reduction in Acidic Media. Carbon 78-84 proline dehydrogenase 1 Homo sapiens 61-64 30203428-3 2018 The pyrolyzed co-doped carbon acting as a metal-free electrocatalyst shows an enhanced activity for ORR in acidic medium, even under poisoning conditions (SOx , NOx , and POx ). Carbon 23-29 proline dehydrogenase 1 Homo sapiens 171-174 30371699-1 2018 In this work, we report anomalous descriptions of bending modes of the smallest carbon-carbon double bonded molecule ethylene with the MP2 method. Carbon 80-86 tryptase pseudogene 1 Homo sapiens 135-138 30371699-1 2018 In this work, we report anomalous descriptions of bending modes of the smallest carbon-carbon double bonded molecule ethylene with the MP2 method. Carbon 87-93 tryptase pseudogene 1 Homo sapiens 135-138 29980062-4 2018 The transition of electrons localized in different sized sub-domain of the sp2 bonded carbons having different values of highest occupied molecular orbital (HOMO) -lowest unoccupied molecular orbital (LUMO) gap may likely to be responsible for the observed PL emission in rG1 and rG2 at different excitation wavelengths. Carbon 86-93 myosin light chain, phosphorylatable, fast skeletal muscle Rattus norvegicus 280-283 29417337-1 2018 We showed previously that natriuretic peptide receptor-C (NPR-C) agonist, C-ANP4-23, attenuated the enhanced expression of Gialpha proteins in vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHR) through the inhibition of enhanced oxidative stress. Carbon 55-56 natriuretic peptide receptor 3 Rattus norvegicus 58-63 30388796-0 2018 Poly(vinylidene fluoride) and Carbon Derivative Structures from Eco-Friendly MOF-5 for Supercapacitor Electrode Preparation with Improved Electrochemical Performance. Carbon 30-36 ciliogenesis associated kinase 1 Homo sapiens 64-67 30317900-0 2018 Role of p53 in the chronic pulmonary immune response to tangled or rod-like multi-walled carbon nanotubes. Carbon 89-95 transformation related protein 53, pseudogene Mus musculus 8-11 30005407-7 2018 Carbon ion beams irradiation up-regulated the expression levels of C-REPEAT BINDING FACTORS (CBFs), INDUCER OF CBF EXPRESSION 1 (ICE1), ICE2, CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 3 (CAMTA3) and cold-regulated COR genes, in response to cold stress. Carbon 0-6 signal responsive 1 Arabidopsis thaliana 142-186 30005407-7 2018 Carbon ion beams irradiation up-regulated the expression levels of C-REPEAT BINDING FACTORS (CBFs), INDUCER OF CBF EXPRESSION 1 (ICE1), ICE2, CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 3 (CAMTA3) and cold-regulated COR genes, in response to cold stress. Carbon 0-6 signal responsive 1 Arabidopsis thaliana 188-194 30355670-1 2018 Grf10, a homeodomain-containing transcription factor, regulates adenylate and one-carbon metabolism and morphogenesis in the human fungal pathogen Candida albicans Here, we identified functional domains and key residues involved in transcription factor activity using one-hybrid and mutational analyses. Carbon 82-88 Pho2p Saccharomyces cerevisiae S288C 0-5 30355670-10 2018 Grf10, a critical homeodomain transcription factor, controls purine and one-carbon metabolism in response to adenine limitation, and Grf10 is necessary for the yeast-to-hypha morphological switching, a known virulence factor. Carbon 76-82 Pho2p Saccharomyces cerevisiae S288C 0-5 30348171-3 2018 Through a quantitative proteomic screen, we previously identified candidate astroglial factors, such as matrix metalloproteinase-3 (Mmp3) and follistatin-like 1 (Fstl1), in polyl:C-induced neurodevelopmental impairment. Carbon 179-180 follistatin-like 1 Mus musculus 142-160 30348171-3 2018 Through a quantitative proteomic screen, we previously identified candidate astroglial factors, such as matrix metalloproteinase-3 (Mmp3) and follistatin-like 1 (Fstl1), in polyl:C-induced neurodevelopmental impairment. Carbon 179-180 follistatin-like 1 Mus musculus 162-167 30364208-0 2018 Photocatalytic Activation of Saturated C-H Bond Over the CdS Mixed-Phase Under Visible Light Irradiation. Carbon 39-40 CDP-diacylglycerol synthase 1 Homo sapiens 57-60 30416852-9 2018 However, the weight (mean +- SEM) of pancreas at the end of the study was higher in blank c-SLN group (223.6 +- 42.2 mg) compared to low (138.0 +- 26.0 mg; not significant [NS]), medium (145.0 +- 9.0 mg; NS), and high (133.8 +- 20.3 mg; NS) ACS c-SLN treated groups, demonstrating the efficacy of ACS c-SLN nanoformulations. Carbon 40-41 sarcolipin Mus musculus 92-95 29536156-6 2018 Spt10p helps in maintaining the cell size by regulating the amount of carbon flux into the phospholipid constituents of the cell membranes. Carbon 70-76 Spt10p Saccharomyces cerevisiae S288C 0-6 30140797-8 2018 The wave packet motion, visible only for the bromine leaving group, can be related to the crucial role of the central carbon atom, which undergoes rehybridization from sp3 to sp2 during the photoinduced bond cleavage. Carbon 118-124 Ser7 Drosophila melanogaster 168-171 30140797-8 2018 The wave packet motion, visible only for the bromine leaving group, can be related to the crucial role of the central carbon atom, which undergoes rehybridization from sp3 to sp2 during the photoinduced bond cleavage. Carbon 118-124 Ser7 Drosophila melanogaster 175-178 29894929-7 2018 Interestingly, the PhP under study were biodegraded even in the absence of additional carbon source, with 85% of ciprofloxacin removed under sulfate-reducing conditions and 62% and 83% of ciprofloxacin and estradiol removed, respectively, under nitrate-reducing conditions. Carbon 86-92 N-acylsphingosine amidohydrolase 1 Homo sapiens 19-22 30105344-2 2018 Herein, two new kinds of Ni (POxN3-x)2/NPC and Co (POxN3-x)2/NPC (NPC: N, P-co-doped carbon) are synthesized through a facile post-treatment of nickel- or cobalt-phytic acid xerogel, followed by an annealing procedure under an argon and ammonia atmosphere at 800 C. The as-prepared catalysts exhibit outstanding catalytic activities for both the oxygen reduction and evolution reactions, which are comparable to those of Pt/C and IrO2. Carbon 85-91 NPC intracellular cholesterol transporter 1 Homo sapiens 29-49 30068074-3 2018 The onset potential for the electrochemical recycling of TTF + on carbon was set at a potential 500 mV more positive than the potential required for the direct reduction of protons. Carbon 66-72 ras homolog family member H Homo sapiens 57-60 30028452-0 2018 Organophosphoric acid-derived CoP quantum dots@S,N-codoped graphite carbon as a trifunctional electrocatalyst for overall water splitting and Zn-air batteries. Carbon 68-74 caspase recruitment domain family member 16 Homo sapiens 30-33 30028452-2 2018 Herein, we demonstrate a facile strategy for the preparation of CoP quantum dots (QDs) embedded in S,N-codoped graphite carbon (CoP@SNC) by using organophosphoric acid as both phosphorus and carbon sources. Carbon 120-126 caspase recruitment domain family member 16 Homo sapiens 64-67 30028452-2 2018 Herein, we demonstrate a facile strategy for the preparation of CoP quantum dots (QDs) embedded in S,N-codoped graphite carbon (CoP@SNC) by using organophosphoric acid as both phosphorus and carbon sources. Carbon 120-126 caspase recruitment domain family member 16 Homo sapiens 128-131 30028452-2 2018 Herein, we demonstrate a facile strategy for the preparation of CoP quantum dots (QDs) embedded in S,N-codoped graphite carbon (CoP@SNC) by using organophosphoric acid as both phosphorus and carbon sources. Carbon 191-197 caspase recruitment domain family member 16 Homo sapiens 64-67 30028452-2 2018 Herein, we demonstrate a facile strategy for the preparation of CoP quantum dots (QDs) embedded in S,N-codoped graphite carbon (CoP@SNC) by using organophosphoric acid as both phosphorus and carbon sources. Carbon 191-197 caspase recruitment domain family member 16 Homo sapiens 128-131 30028452-3 2018 Benefiting from the strong coupling and synergistic effect between CoP QDs and highly conductive S,N-codoped carbon, well-structured porosity and high specific surface area, the resulting CoP@SNC exhibits excellent activities for oxygen evolution reaction (OER), hydrogen evolution reaction (HER), and oxygen reduction reaction (ORR), making it a trifunctional electro-catalyst for overall water splitting and rechargeable Zn-air batteries. Carbon 109-115 caspase recruitment domain family member 16 Homo sapiens 188-191 29903710-7 2018 Rates of contraindicated concomitant medication use differed significantly by ART regimen; the highest rate (3.2%) was for darunavir plus ritonavir plus emtricitabine-tenofovir disoproxil fumarate (DRV plus RTV plus FTC/TDF), followed by elvitegravir-cobicistat-emtricitabine-tenofovir disoproxil fumarate (EVG/c/FTC/TDF)(2.8%). Carbon 9-10 sex determining region Y Homo sapiens 220-223 29903710-7 2018 Rates of contraindicated concomitant medication use differed significantly by ART regimen; the highest rate (3.2%) was for darunavir plus ritonavir plus emtricitabine-tenofovir disoproxil fumarate (DRV plus RTV plus FTC/TDF), followed by elvitegravir-cobicistat-emtricitabine-tenofovir disoproxil fumarate (EVG/c/FTC/TDF)(2.8%). Carbon 9-10 sex determining region Y Homo sapiens 317-320 28659017-4 2018 The adsorption property of GAC was noticed to be an effective factor for catalytic activity by increasing the residence time, although the higher retention time prevented the accurate determination of chlorine and carbon balance. Carbon 214-220 glutaminase Homo sapiens 27-30 30061540-7 2018 Finally, these studies show a significant increase in the relative biological effectiveness (RBE) of high LET SOBP carbon and iron ions in HR and PARP mutants. Carbon 115-121 poly [ADP-ribose] polymerase 1 Cricetulus griseus 146-150 30047045-10 2018 The molecular docking of C-798 and C-800 into the myosin S1 region showed that these thiacalix[4]arenes could interact with Zn cation bond by myosin amino acid residues near the ATPase active site. Carbon 25-26 myosin heavy chain 14 Homo sapiens 50-56 31698154-0 2020 Carbon nano dot decorated copper nanowires for SERS-Fluorescence dual-mode imaging/anti-microbial activity and enhanced angiogenic activity. Carbon 0-6 seryl-tRNA synthetase 1 Homo sapiens 47-51 31932507-3 2020 GDE2 trafficking is directed by C-terminal tail sequences that determine GDE2"s ability to cleave GPI-anchored glypican-6 (GPC6) and induce a neuronal differentiation program. Carbon 32-33 glypican 6 Mus musculus 98-121 31932507-3 2020 GDE2 trafficking is directed by C-terminal tail sequences that determine GDE2"s ability to cleave GPI-anchored glypican-6 (GPC6) and induce a neuronal differentiation program. Carbon 32-33 glypican 6 Mus musculus 123-127 32034121-0 2020 Serine-glycine-one-carbon metabolism: vulnerabilities in MYCN-amplified neuroblastoma. Carbon 0-25 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 57-61 31875404-6 2020 As a result, the solar cells basing on a configuration of FTO/TiO2/CsPbBr3/Carbon exhibit a power conversion efficiency of 6.12%. Carbon 75-81 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 58-61 31927909-3 2020 Herein, we demonstrate the building of high-performance HTL/ETL-free, self-powered CsPbIBr2 PD with simplified architecture of FTO/CsPbIBr2/carbon upon interfacial modification by polyethyleneimine (PEI). Carbon 140-146 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 127-130 31848666-0 2020 Heme oxygenase-1 regulates autophagy through carbon-oxygen to alleviate deoxynivalenol-induced hepatic damage. Carbon 45-51 heme oxygenase 1 Homo sapiens 0-16 31772275-5 2020 ILF3 is critical in regulating the SGOC pathway by directly regulating the mRNA stability of SGOC genes, thereby increasing SGOC genes expression and facilitating tumor growth. Carbon 35-39 interleukin enhancer binding factor 3 Homo sapiens 0-4 31772275-5 2020 ILF3 is critical in regulating the SGOC pathway by directly regulating the mRNA stability of SGOC genes, thereby increasing SGOC genes expression and facilitating tumor growth. Carbon 93-97 interleukin enhancer binding factor 3 Homo sapiens 0-4 31772275-5 2020 ILF3 is critical in regulating the SGOC pathway by directly regulating the mRNA stability of SGOC genes, thereby increasing SGOC genes expression and facilitating tumor growth. Carbon 93-97 interleukin enhancer binding factor 3 Homo sapiens 0-4 31772275-7 2020 Significantly, combination of SGOC inhibitor and the anti-EGFR monoclonal antibody cetuximab can hinder the growth of patient-derived xenografts that sustain high ERK-ILF3 levels. Carbon 30-34 interleukin enhancer binding factor 3 Homo sapiens 167-171 31772275-9 2020 Our findings indicate that clinical evaluation of SGOC inhibitor is warranted for CRC patients with ILF3 overexpression. Carbon 50-54 interleukin enhancer binding factor 3 Homo sapiens 100-104 31820547-6 2020 Two RBM10 splicing mutants, one with F345A/F347A and the other with only the C-terminal half (401-930), were sufficient to cause growth arrest, while an RBM10 mutant with cytoplasmic localization forced by an NES did not show growth arrest. Carbon 77-78 RNA binding motif protein 10 Homo sapiens 4-9 31857182-0 2020 Balanced Th1/Th2 immune response induced by a MSP1a functional motif coupled to multiwalled carbon nanotubes as anti-anaplasmosis vaccine in murine model. Carbon 92-98 heart and neural crest derivatives expressed 2 Mus musculus 13-16 31550400-6 2020 We show that the C-terminal cleaved product of apple RIN4 (MdRIN4) but not AtRIN4 is necessary and sufficient for MR5 activation. Carbon 17-18 RPM1 interacting protein 4 Arabidopsis thaliana 53-57 31957981-2 2020 Yet, the energy density of ASC is severely limited by the low capacitance of the anode side, which commonly uses the carbon-based nanomaterials. Carbon 117-123 steroid sulfatase Homo sapiens 27-30 31971671-0 2020 ZIF-8@ZIF-67-Derived Nitrogen-Doped Porous Carbon Confined CoP Polyhedron Targeting Superior Potassium-Ion Storage. Carbon 43-49 caspase recruitment domain family member 16 Homo sapiens 59-62 31971671-4 2020 The synthesis of ZIF-8@ZIF-67 derived nitrogen-doped porous carbon confined CoP polyhedron architectures (NC@CoP/NC) to function as innovative KIB anode materials is reported. Carbon 60-66 caspase recruitment domain family member 16 Homo sapiens 76-79 30047045-10 2018 The molecular docking of C-798 and C-800 into the myosin S1 region showed that these thiacalix[4]arenes could interact with Zn cation bond by myosin amino acid residues near the ATPase active site. Carbon 25-26 myosin heavy chain 14 Homo sapiens 142-148 29770593-7 2018 Finally, constructing M-Nx moieties is proposed as the most promising engineering strategy for stable N-C-based electrocatalysts. Carbon 104-105 keratin 86 Homo sapiens 22-26 10048586-14 1999 Taken together, the data suggests murine PKCepsilon expression potently reduces the growth of yeast cells in a carbon source-dependent fashion by affecting progression through multiple points within the cell cycle. Carbon 111-117 protein kinase C, epsilon Mus musculus 41-51 10025828-5 1999 MAO metabolism of PHEN was inhibited at the tracer level by substituting deuterium atoms for the two hydrogen atoms at the alpha-carbon side chain position to yield the MAO-resistant analog D2-PHEN. Carbon 129-135 monoamine oxidase A Rattus norvegicus 0-3 29652218-5 2018 Results indicate that with an (empty bed residence time (EBRT) of 0.15 sec for the gas through the GAC-packed space, around 60% of the influent NO2 of 54 ppm could be removed, and 47% of the removed NO2 was converted by and desorbed from the carbon as NO. Carbon 242-248 glutaminase Homo sapiens 99-102 30087547-5 2018 Under normoxia, blood flow velocity in precapillary arterioles were significantly elevated in heme oxygenase-2-null mice vs controls, while metabolic intermediates of central carbon metabolism and glutamate synthesis were elevated in the brain of heme oxygenase-2-null mice, suggesting greater metabolic demands to induce hyperemia in these mice. Carbon 175-181 heme oxygenase 2 Mus musculus 247-263 29676817-2 2018 Diyne cross-metathesis (DYCM) studies with 13 C-labeled diyne PhC 13 C-13 C CPh (3*) revealed that this reaction proceeds through reversible carbon-carbon triple-bond cleavage and formation according to the conventional mechanism of alkyne metathesis. Carbon 141-147 carboxypeptidase E Homo sapiens 76-79 29676817-2 2018 Diyne cross-metathesis (DYCM) studies with 13 C-labeled diyne PhC 13 C-13 C CPh (3*) revealed that this reaction proceeds through reversible carbon-carbon triple-bond cleavage and formation according to the conventional mechanism of alkyne metathesis. Carbon 148-154 carboxypeptidase E Homo sapiens 76-79 9855012-8 1998 These results are in line with previous studies on the enantioselectivity of purified GSTP1-1 towards the DE isomers of benzo[a]pyrene and benzo[c]phenanthrene showing that enantiomers with (R)-configuration at the benzylic oxiranyl carbon are better substrates than those with (S)-configuration. Carbon 233-239 glutathione S-transferase P 1 Cricetulus griseus 86-93 30018733-4 2018 Five genes in one-carbon metabolism pathway including MTHFR 677, MTHFR 1298, MTR 2756, MTRR 66, and DHFR 19bp together with demographics, lifestyle, and dietary intake factors were examined in association with BC risks. Carbon 18-24 dihydrofolate reductase Homo sapiens 100-104 31990451-5 2020 The as-formed prelithiated hard carbon (pHC) has a thinner, denser, and more robust solid electrolyte interface layer consisting of uniformly distributed LiF, thus demonstrating a very high ICE, high power, and stable cyclability. Carbon 32-38 LIF interleukin 6 family cytokine Homo sapiens 154-157 32013110-4 2020 The p42, p44, p46, p48 and p52 isoform proteins were each able to induce RNase-mediated rRNA cleavage in response to poly(I:C) when overexpressed in HEK293 cells. Carbon 124-126 cyclin dependent kinase 20 Homo sapiens 4-7 9873573-2 1998 Bioisosteric replacement of the C-6 carbon atom in piperidine I and piperazine II with S, O, and N heteroatoms is described. Carbon 36-42 complement C6 Homo sapiens 32-35 29862399-1 2018 A novel non-enzymatic electrochemical sensor for highly sensitive and selective detection of dopamine was developed based on a 3,4,9,10-perylene tetracarboxylic acid functionalized graphene-multiwalled carbon nanotube-gold nanoparticle nanocomposite modified glassy carbon electrode (PTCA-RGO-MWCNTs-Au NPs/GCE). Carbon 202-208 aminomethyltransferase Homo sapiens 307-310 9614103-1 1998 Glucose-6-phosphate dehydrogenase (G6PDH) controls the flow of carbon through the pentose phosphate pathway and also produces NADPH needed for maintenance of reduced glutathione and reductive biosynthesis. Carbon 63-69 glucose-6-phosphate dehydrogenase Rattus norvegicus 0-33 30229020-1 2018 Air-sea flux exchanges influence the climate condition and the global carbon-moisture cycle. Carbon 70-76 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 4-7 29890741-4 2018 A high efficiency of 10.7% was achieved for the device with spongy carbon film deposited on a separated FTO-substrate as a counter electrode under one sun illumination, which is the highest efficiency (as 2.5 times as previous efficiency) ever recorded in perovskite solar cells with a such spongy carbon/FTO composite counter electrode. Carbon 67-73 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 104-107 29890741-4 2018 A high efficiency of 10.7% was achieved for the device with spongy carbon film deposited on a separated FTO-substrate as a counter electrode under one sun illumination, which is the highest efficiency (as 2.5 times as previous efficiency) ever recorded in perovskite solar cells with a such spongy carbon/FTO composite counter electrode. Carbon 67-73 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 305-308 29890741-4 2018 A high efficiency of 10.7% was achieved for the device with spongy carbon film deposited on a separated FTO-substrate as a counter electrode under one sun illumination, which is the highest efficiency (as 2.5 times as previous efficiency) ever recorded in perovskite solar cells with a such spongy carbon/FTO composite counter electrode. Carbon 298-304 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 104-107 29890741-5 2018 The preparation techniques of high-class perovskite thin films under ambient conditions and the cheap spongy carbon/FTO composite counter electrode are beneficial for large-scale applications and commercialization. Carbon 109-115 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 116-119 31992583-4 2020 All displayed context-dependent differences in their ability to detect N- or C-terminal Myc-tagged proteins. Carbon 77-78 MYC proto-oncogene, bHLH transcription factor Homo sapiens 88-91 31721323-0 2020 Fe doped CoP flower-like microstructure on carbon membrane as integrated electrode with enhanced sodium ion storage. Carbon 43-49 caspase recruitment domain family member 16 Homo sapiens 9-12 31721323-3 2020 Considering those strategies, we designed the flower-like Fe doped CoP consisted of the micro sheets grown on the carbon membrane (CM, the leaves as precursor) by hydrothermal method and in-situ phosphorization. Carbon 114-120 caspase recruitment domain family member 16 Homo sapiens 67-70 31721323-6 2020 The hierarchical Fe doped CoP directly grown on the carbon membrane could increase the active sites for sodium species intercalation and further promote the internal electron conduction in the Fe doped CoP/CM electrode. Carbon 52-58 caspase recruitment domain family member 16 Homo sapiens 26-29 31721323-6 2020 The hierarchical Fe doped CoP directly grown on the carbon membrane could increase the active sites for sodium species intercalation and further promote the internal electron conduction in the Fe doped CoP/CM electrode. Carbon 52-58 caspase recruitment domain family member 16 Homo sapiens 202-205 31980627-3 2020 Kindlin-2, through its C-terminal region, binds to and stabilizes MafA, which activates insulin expression. Carbon 23-24 fermitin family member 2 Mus musculus 0-9 29685969-2 2018 The compounds with linker lengths of 6 and 7 carbon atoms were the most potent in histone deacetylase (HDAC) inhibition, and were specific submicromolar inhibitors of the HDAC1, HDAC6 and HDAC8 isoforms. Carbon 45-51 histone deacetylase 8 Homo sapiens 188-193 9614103-1 1998 Glucose-6-phosphate dehydrogenase (G6PDH) controls the flow of carbon through the pentose phosphate pathway and also produces NADPH needed for maintenance of reduced glutathione and reductive biosynthesis. Carbon 63-69 glucose-6-phosphate dehydrogenase Rattus norvegicus 35-40 9637009-1 1998 Studies with pure cultures growing in laboratory media indicated that beta-glucuronidase expression of Escherichia coli S1 was considerably affected by starch added to the medium as the only carbon source. Carbon 191-197 glucuronidase beta Homo sapiens 70-88 29772783-2 2018 AtPAP2 was previously shown to localize to both chloroplasts and mitochondria and to modulate carbon metabolism in Arabidopsis. Carbon 94-100 Purple acid phosphatases superfamily protein Arabidopsis thaliana 0-6 31907496-3 2020 In addition, the corresponding solid-state CoNi2S4//AC HSC could achieve a high energy density of 35.8 W h kg-1 at a power density of 800.0 W kg-1, with nearly no change when tested at 0 C and 50 C, and possessed excellent long-term electrochemical cycling stability of 132.3% after 50 000 cycles; the solid-state hybrid supercapacitor using biomass-derived carbon (BC) as the negative electrode (CoNi2S4//BC HSC) could also deliver a high energy density of 38.9 W h kg-1 at a power density of 850.0 W kg-1 and the specific capacitance retention was 101.2% after cycling for 50 000 times. Carbon 360-366 fucosyltransferase 1 (H blood group) Homo sapiens 55-58 9467872-10 1997 Mitochondrial phosphoenolpyruvate carboxykinase in enterocytes in vivo could convert glycolysis-derived phosphoenolpyruvate to oxaloacetate that, with acetyl CoA, could form citrate for export to support cytosolic lipogenesis as an activator of acetyl CoA carboxylase, a source of carbon via ATP:citrate lyase and of NADPH via NADP:malate dehydrogenase or NADP:isocitrate dehydrogenase. Carbon 281-287 phosphoenolpyruvate carboxykinase [GTP], mitochondrial Oryctolagus cuniculus 0-47 32010139-7 2019 Analysis of the binding of chimeric MBP-HA peptides demonstrated that the observed difference between MBP153-161, MBP90-98, and HA peptide epitopes is caused by the lack of anchor residues in the C-terminal part of the MBP peptides resulting in a moderate occupation of P6/7 and P9 pockets of HLA-DRB1*01:01 by MBP153-161 and MBP90-98 peptides in contrast to HA308-316 peptide. Carbon 196-197 exosome component 9 Homo sapiens 270-281 29501167-4 2018 An electrochemical sensor was constructed based on glass carbon electrode (GCE) modified by MoS2 nanosheets obtained in DMF, which exhibits relatively higher sensitivity to Cd2+ detection and lower cytotoxicity against MCF-7 cells. Carbon 57-63 CD2 molecule Homo sapiens 173-176 29690640-7 2018 Using an in vivo model with genetically modified mice lacking caveolin-1, it was possible to demonstrate that carbon nanoparticles in vivo trigger EGFR downstream signaling cascades via caveolin-1. Carbon 110-116 caveolin 1, caveolae protein Mus musculus 62-72 29690640-7 2018 Using an in vivo model with genetically modified mice lacking caveolin-1, it was possible to demonstrate that carbon nanoparticles in vivo trigger EGFR downstream signaling cascades via caveolin-1. Carbon 110-116 epidermal growth factor receptor Mus musculus 147-151 29690640-7 2018 Using an in vivo model with genetically modified mice lacking caveolin-1, it was possible to demonstrate that carbon nanoparticles in vivo trigger EGFR downstream signaling cascades via caveolin-1. Carbon 110-116 caveolin 1, caveolae protein Mus musculus 186-196 29541710-0 2018 Carbon dots as analytical tools for sensing of thioredoxin reductase and screening of cancer cells. Carbon 0-6 peroxiredoxin 5 Homo sapiens 47-68 29541710-3 2018 Herein, an easily engineered "Turn ON" fluorescent sensor probe has been synthesized for the detection of TrxR and cell imaging using carbon dots. Carbon 134-140 peroxiredoxin 5 Homo sapiens 106-110 32021280-2 2020 The spen paralogue and orthologue C-terminal domain containing 1 (SPOCD1) is a newly identified molecule that has been indicated to discriminate progressive in human solid tumors. Carbon 34-35 SPOC domain containing 1 Homo sapiens 66-72 31578296-0 2020 Conserved CxnC motifs in Kaposi"s sarcoma-associated herpesvirus ORF66 are required for viral late gene expression and are essential for its interaction with ORF34. Carbon 0-1 ORF34;ORF36 Human gammaherpesvirus 8 158-163 31578296-5 2020 We show that ORF66 is incorporated into the vTA complex primarily through its interaction with ORF34, which is dependent upon a set of four conserved cysteine-rich motifs in the C-terminal domain of ORF66. Carbon 178-179 family with sequence similarity 120C Homo sapiens 95-100 9379441-5 1997 In particular the combination of an N-n-propyl group, an S-alkyl chain between four and six carbons in length, and a fluorine atom ortho to the aromatic OCH3 provides compounds with sub-nanomolar affinities for both receptor subtypes, and with ETA/ETB ratios close to 1. Carbon 92-99 endothelin receptor type A Rattus norvegicus 244-247 31613014-2 2020 These structures possess 12 intradimer contacts <3.40 A, with the shortest intra p - [TTF xxx TCNE] separations involving 2-center (2c) C-S and 3c C-C-C orbital overlap contributions between the [TTF] d + and [TCNE] d - . Carbon 150-158 ras homolog family member H Homo sapiens 90-93 31613014-2 2020 These structures possess 12 intradimer contacts <3.40 A, with the shortest intra p - [TTF xxx TCNE] separations involving 2-center (2c) C-S and 3c C-C-C orbital overlap contributions between the [TTF] d + and [TCNE] d - . Carbon 150-158 ras homolog family member H Homo sapiens 202-205 29156408-1 2018 In this study, we aim to design a simple and effective electrochemical DNA biosensor based on a carbon paste electrode modified with ds-DNA/poly(L-cysteine)/Fe3O4 nanoparticles-graphene oxide (ds-DNA/p(L-Cys)/Fe3O4 NPs-GO/CPE) for sensitive detection of adenine (A) and guanine (G). Carbon 96-102 carboxypeptidase E Homo sapiens 222-225 29195219-0 2018 Nanoconjugates of ferrocene and carbon-encapsulated iron nanoparticles as sensing platforms for voltammetric determination of ceruloplasmin in blood. Carbon 32-38 ceruloplasmin Homo sapiens 126-139 9379441-5 1997 In particular the combination of an N-n-propyl group, an S-alkyl chain between four and six carbons in length, and a fluorine atom ortho to the aromatic OCH3 provides compounds with sub-nanomolar affinities for both receptor subtypes, and with ETA/ETB ratios close to 1. Carbon 92-99 endothelin receptor type B Rattus norvegicus 248-251 29202438-2 2018 In present work, a spatial-resolved dual-signal-output electrochemiluminescent (ECL) ratiometric assay platform was constructed for sensitive detection of prostate specific antigen (PSA) on a dual-disk glassy carbon electrode. Carbon 209-215 kallikrein related peptidase 3 Homo sapiens 155-180 9172357-1 1997 Silencing of MIG1, a transcription factor imposing carbon catabolite repression on invertase, was attempted, either by disrupting the gene or by expressing antisense copies of the gene. Carbon 51-57 transcription factor MIG1 Saccharomyces cerevisiae S288C 13-17 29490139-4 2018 The metals or metal oxide nanoparticles arising from alginates could catalyze the pyrolysis intermediates of EVA into graphene and amorphous carbon, which could bind the inorganic compounds (the decomposition products of MH and APTES) together and form some more protective barriers. Carbon 141-147 myelin protein zero like 2 Homo sapiens 109-112 29437258-0 2018 Highly Efficient Photocatalytic System Constructed from CoP/Carbon Nanotubes or Graphene for Visible-Light-Driven CO2 Reduction. Carbon 60-66 caspase recruitment domain family member 16 Homo sapiens 56-59 31906450-3 2020 We showed that STY46 was induced by (1) abscisic acid and prolonged darkness, (2) by abiotic stressors, including salinity and osmotic stress, and (3) by conditions associated with carbon starvation. Carbon 181-187 ACT-like protein tyrosine kinase family protein Arabidopsis thaliana 15-20 31906450-5 2020 However, Arabidopsis with high levels of STY46 transcripts (OE-25) grew faster at the early seedling stage, had higher photosynthetic rates, and more carbon was stored as protein in the seeds under control conditions. Carbon 150-156 ACT-like protein tyrosine kinase family protein Arabidopsis thaliana 41-46 31929179-2 2020 The C-terminal region of MUL1 faces the cytoplasm and contains the RING domain (MUL1-RING) where the Ub~E2 thioester binds. Carbon 4-5 mitochondrial E3 ubiquitin protein ligase 1 Homo sapiens 25-29 31929179-2 2020 The C-terminal region of MUL1 faces the cytoplasm and contains the RING domain (MUL1-RING) where the Ub~E2 thioester binds. Carbon 4-5 mitochondrial E3 ubiquitin protein ligase 1 Homo sapiens 80-84 9225860-3 1997 Subsequent experiments showed that high level expression of the galactokinase cDNA did not complement the peroxisomal assembly defect, but instead permitted the cells to grow on agar plates in the absence of an external carbon source. Carbon 220-226 galactokinase Saccharomyces cerevisiae S288C 64-77 31473532-7 2020 LCCPs with carbon chains > C20 were detected in dust and hair samples, possibly indicating the use of wax grade LCCP formulations. Carbon 11-17 angiomotin like 2 Homo sapiens 0-4 31931990-3 2020 The results presenting within the text are giving insights to the effect of carbon nanotubes on the catalytic and structural characteristics of different proteins, such as cytochrome c from equine heart (cyt c) and laccase from Trametes versicolor (TvL), either when they are used as additives in the reaction medium or as supports for protein immobilization. Carbon 76-82 cytochrome c, somatic Equus caballus 172-184 31520495-5 2020 Using this "Push-and-Pull" approach, the transgenic SUT1 plants displayed increased sucrose phloem loading and carbon movement from source to sink causing higher sucrose levels in developing pea seeds. Carbon 111-117 solute carrier family 13 member 4 Homo sapiens 52-56 29336543-2 2018 Here, we report in vitro profiling of HDAC11 deacylase activities, and our data unequivocally show that the enzyme efficiently removes acyl moieties spanning 8-18 carbons from the side chain nitrogen of the lysine residue of a peptidic substrate. Carbon 163-170 histone deacetylase 11 Homo sapiens 38-44 29096367-9 2018 The voltammetric SMN carbon nanofiber-based immunosensor showed high sensitivity (detection limit of 0.75pg/ml) and selectivity against other proteins such as cystic fibrosis transmembrane conductance regulator (CFTR) and dystrophin (DMD). Carbon 21-27 dystrophin Homo sapiens 222-232 29451291-4 2018 The CoII-MOF modified glassy carbon electrode (GCE) shows good electrocatalytic activity towards glucose oxidation. Carbon 29-35 guanylate cyclase 2E, pseudogene Homo sapiens 47-50 9213396-2 1997 HIV-1 gp120 binding proteins of the CD4-negative and Gal-C-negative, non-productively infectable human glioblastoma cell line D54 were purified by affinity chromatography over a gp120-conjugated sepharose column and identified by peptide microsequencing. Carbon 36-37 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 6-11 29384648-0 2018 Well-Coupled Nanohybrids Obtained by Component-Controlled Synthesis and in Situ Integration of Mn xPd y Nanocrystals on Vulcan Carbon for Electrocatalytic Oxygen Reduction. Carbon 127-133 ERCC excision repair 2, TFIIH core complex helicase subunit Homo sapiens 98-101 29507286-6 2018 We also identify interactions of sea ice with phytoplankton growth and ocean circulation patterns, which have important implications for glacial North Pacific Intermediate Water formation and potentially North Pacific abyssal carbon storage. Carbon 226-232 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 33-36 31712308-2 2019 The C-terminal region of cardiac troponin T (TnT), a tropomyosin-associated protein, is required for full TnT inactivation at low Ca2+ and for limiting its activation at saturating Ca2+ Here, we investigated whether basic residues in this TnT region are involved in these activities, whether the TnT C terminus undergoes Ca2+-dependent conformational changes, and whether these residues affect cardiac muscle contraction. Carbon 4-5 troponin T1, slow skeletal type Homo sapiens 45-48 31712308-2 2019 The C-terminal region of cardiac troponin T (TnT), a tropomyosin-associated protein, is required for full TnT inactivation at low Ca2+ and for limiting its activation at saturating Ca2+ Here, we investigated whether basic residues in this TnT region are involved in these activities, whether the TnT C terminus undergoes Ca2+-dependent conformational changes, and whether these residues affect cardiac muscle contraction. Carbon 4-5 troponin T1, slow skeletal type Homo sapiens 106-109 31712308-2 2019 The C-terminal region of cardiac troponin T (TnT), a tropomyosin-associated protein, is required for full TnT inactivation at low Ca2+ and for limiting its activation at saturating Ca2+ Here, we investigated whether basic residues in this TnT region are involved in these activities, whether the TnT C terminus undergoes Ca2+-dependent conformational changes, and whether these residues affect cardiac muscle contraction. Carbon 4-5 troponin T1, slow skeletal type Homo sapiens 106-109 31712308-2 2019 The C-terminal region of cardiac troponin T (TnT), a tropomyosin-associated protein, is required for full TnT inactivation at low Ca2+ and for limiting its activation at saturating Ca2+ Here, we investigated whether basic residues in this TnT region are involved in these activities, whether the TnT C terminus undergoes Ca2+-dependent conformational changes, and whether these residues affect cardiac muscle contraction. Carbon 4-5 troponin T1, slow skeletal type Homo sapiens 106-109 31712308-2 2019 The C-terminal region of cardiac troponin T (TnT), a tropomyosin-associated protein, is required for full TnT inactivation at low Ca2+ and for limiting its activation at saturating Ca2+ Here, we investigated whether basic residues in this TnT region are involved in these activities, whether the TnT C terminus undergoes Ca2+-dependent conformational changes, and whether these residues affect cardiac muscle contraction. Carbon 130-131 troponin T1, slow skeletal type Homo sapiens 45-48 9162038-0 1997 1alpha,25-dihydroxyvitamin D3-24-hydroxylase (CYP24) hydroxylates the carbon at the end of the side chain (C-26) of the C-24-fluorinated analog of 1alpha,25-dihydroxyvitamin D3. Carbon 70-76 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 46-51 31712308-6 2019 Forster Resonance Energy Transfer analyses indicated that the C-terminal TnT region approached Cys-190 of tropomyosin as actin filaments transitioned to the inactive B state; that transition was abolished with high-alanine TnT. Carbon 62-63 troponin T1, slow skeletal type Homo sapiens 73-76 31712308-6 2019 Forster Resonance Energy Transfer analyses indicated that the C-terminal TnT region approached Cys-190 of tropomyosin as actin filaments transitioned to the inactive B state; that transition was abolished with high-alanine TnT. Carbon 62-63 troponin T1, slow skeletal type Homo sapiens 223-226 29341380-2 2018 A Mott-Schottky catalyst composed of Ni nanoparticles and tailorable nitrogen-doped carbon-foam (Ni/NCF) and thus tunable adsorption energy is presented for highly efficient and selective dehydrogenation of gas-phase methanol to hydrogen and CO even under relatively high weight hourly space velocities (WHSV). Carbon 84-90 neutrophil cytosolic factor 4 Homo sapiens 100-103 29374570-5 2018 This is the first time naphthoquinone dimer (1), as a novel carbon skeleton possessing IDO inhibitory activity, was reported. Carbon 60-66 indoleamine 2,3-dioxygenase 1 Homo sapiens 87-90 31703893-3 2019 Benzopyran-4-ones 6, 12, 13 and 17 as well as dihydrobenzopyrans 22, 24 and 25 were able to activate hPPARalpha, whereas benzopyran-4-one (7) with C5-carbons in the side chain exhibited hPPARgamma agonism. Carbon 147-157 peroxisome proliferator activated receptor alpha Homo sapiens 101-111 9162038-0 1997 1alpha,25-dihydroxyvitamin D3-24-hydroxylase (CYP24) hydroxylates the carbon at the end of the side chain (C-26) of the C-24-fluorinated analog of 1alpha,25-dihydroxyvitamin D3. Carbon 107-108 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 46-51 31703893-4 2019 According to our previous docking studies, SAR confirm that the hydrophobic nucleus (benzopyran-4-one or dihydrobenzopyran) is essential to activate PPARalpha and/or PPARgamma, and the flexible linker (side alkyl chain) should containg at least C5-carbon atoms to activate PPARgamma. Carbon 245-254 peroxisome proliferator activated receptor alpha Homo sapiens 149-158 29356313-3 2018 Herein, a general approach for the production of 1D porous nitrogen-doped graphitic carbon fibers embedded with active ORR components, (M/MOx , i.e., metal or metal oxide nanoparticles) using a facile two-step electrospinning and annealing process is reported. Carbon 84-90 monooxygenase DBH like 1 Homo sapiens 138-141 9162038-8 1997 These results show that CYP24 catalyzes not only hydroxylation at C-24 and C-23 of 1alpha,25(OH)2D3 but also at C-26 of F2-1alpha,25(OH)2D3, indicating that this enzyme has a broader substrate specificity of the hydroxylation sites than previously considered. Carbon 66-67 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 24-29 9162038-8 1997 These results show that CYP24 catalyzes not only hydroxylation at C-24 and C-23 of 1alpha,25(OH)2D3 but also at C-26 of F2-1alpha,25(OH)2D3, indicating that this enzyme has a broader substrate specificity of the hydroxylation sites than previously considered. Carbon 66-67 cytochrome P450, family 24, subfamily a, polypeptide 1 Rattus norvegicus 24-29 31615841-9 2019 Of note, siRNAs that silenced MAVS and interferon regulatory factor 1 (IRF1) expression reduced OCT3/4 levels after stimulation with poly(I:C); however, an NF-kappaB inhibitor and siRNA-mediated knockdown of proto-oncogene c-Jun did not significantly reduce the mRNA levels. Carbon 140-142 mitochondrial antiviral signaling protein Homo sapiens 30-34 31615841-9 2019 Of note, siRNAs that silenced MAVS and interferon regulatory factor 1 (IRF1) expression reduced OCT3/4 levels after stimulation with poly(I:C); however, an NF-kappaB inhibitor and siRNA-mediated knockdown of proto-oncogene c-Jun did not significantly reduce the mRNA levels. Carbon 140-142 POU class 5 homeobox 1 Homo sapiens 96-102 29316108-2 2018 In contrast, treatment of c-Si3 Tip4 (Tip=2,4,6-i Pr3 C6 H2 ) with styrene and benzil results in ring opening of the three-membered ring to formally yield the [1+2]- and [1+4] cycloaddition product of the isomeric disilenyl silylene to the C=C bond and the 1,2-diketone pi system, respectively. Carbon 54-55 GIPC PDZ domain containing family member 1 Homo sapiens 38-43 9365181-5 1997 The acyl-carbon cleavage reaction of equation 1 is catalysed by sterol 14alpha-demethylases, accounts for several side-chain fission products formed by CYP17 (17alpha-hydroxylase-17,20-lyase), and constitutes a weak property of certain drug metabolizing P450s, when given aliphatic aldehydes as substrates. Carbon 9-15 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 152-157 29316108-2 2018 In contrast, treatment of c-Si3 Tip4 (Tip=2,4,6-i Pr3 C6 H2 ) with styrene and benzil results in ring opening of the three-membered ring to formally yield the [1+2]- and [1+4] cycloaddition product of the isomeric disilenyl silylene to the C=C bond and the 1,2-diketone pi system, respectively. Carbon 240-241 GIPC PDZ domain containing family member 1 Homo sapiens 38-43 29844895-0 2018 An unusual stereoretentive 1,3-quaternary carbon shift resulting in an enantioselective RhII-catalyzed formal [4+1]-cycloaddition between diazo compounds and vinyl ketenes. Carbon 42-48 Rh blood group D antigen Homo sapiens 88-92 29844895-1 2018 Enantioselective quaternary carbon construction in the assembly of cyclopentenones employing a RhII-catalyzed, formal [4+1]-cycloaddition is described. Carbon 28-34 Rh blood group D antigen Homo sapiens 95-99 33417790-6 2019 The Sil-MA water solution with the addition of a photoinitiator (LAP) allows the opening, under UV radiation, of a double carbon-carbon bond and radical polymerization. Carbon 122-128 LAP Homo sapiens 65-68 31817918-5 2019 Further experiments demonstrated that rubioncolin C induced apoptotic and autophagic cell death and inhibited the Akt/mTOR/P70S6K signaling pathway in HCT116 and HepG2 cells. Carbon 38-51 ribosomal protein S6 kinase B1 Homo sapiens 123-129 34057492-1 2019 A rapid, simple, selective and highly sensitive simultaneous determination of Cu(II) and Pb(II) via newly fashioned 5,11,17,23-tetra-tert-butyl-25,27-dihydrazinamidecarbonylmethoxy-26,28-dihydroxycalix[4]arene-grafted multi-walled carbon nanotubes-modified carbon paste electrode (CNT-Calix/CPE) by differential pulse anodic stripping voltammetry (DPASV) has been introduced. Carbon 165-171 carboxypeptidase E Homo sapiens 291-294 9109172-1 1997 Amphiphilic N,N-dimethylalkylamine N-oxides (abbreviation CnNO, n is the number of carbon atoms in the alkyl substituent) modulate the activity of the purified sarcoplasmic reticulum (Ca-Mg)ATPase. Carbon 83-89 dynein axonemal heavy chain 8 Homo sapiens 190-196 31772242-2 2019 In one-carbon cycle, folate acts as a one-carbon carrier and vitamin B12 acts as co-factor for the enzyme methionine synthase. Carbon 7-13 5-methyltetrahydrofolate-homocysteine methyltransferase Mus musculus 106-125 29520285-11 2018 Thus, GS2 has a central role as a regulator between the nitrogen and the carbon cycles via maintaining glutamine-glutamate pool in the chloroplast on the level of substrates, in addition to its function in ammonia assimilation. Carbon 73-79 glutamine synthetase leaf isozyme, chloroplastic Triticum aestivum 6-9 29320187-6 2018 The dispersion energy contributions to BEs in PEn-Au-PEn rise nearly linearly with the number of carbon atoms in the PEn chain. Carbon 97-103 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 46-49 29320187-6 2018 The dispersion energy contributions to BEs in PEn-Au-PEn rise nearly linearly with the number of carbon atoms in the PEn chain. Carbon 97-103 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 53-56 9037103-1 1997 Carbon and nitrogen regulation of UBI4, the stress-inducible polyubiquitin gene of Saccharomyces cerevisiae, was investigated using a UBI4 promoter-LacZ fusion gene (UBI4-LacZ). Carbon 0-6 ubiquitin Saccharomyces cerevisiae S288C 34-38 29320187-6 2018 The dispersion energy contributions to BEs in PEn-Au-PEn rise nearly linearly with the number of carbon atoms in the PEn chain. Carbon 97-103 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 53-56 29422671-6 2018 Therefore, site-specific phosphorylation of TTG1 by SK11/SK12 regulates carbon partitioning between zygotic and maternal sinks in seeds. Carbon 72-78 SKP1-like 12 Arabidopsis thaliana 57-61 29339156-1 2018 Serine hydroxymethyltransferase (SHMT) catalyzes the interconversion of serine and glycine, which is crucial for one carbon metabolism. Carbon 117-123 serine hydroxymethyltransferase 1 Homo sapiens 33-37 29363959-6 2018 Chemically or electrochemically generated Co(I) porphyrins are known to be highly reactive in solutions containing alkyl or aryl halides, and this property was utilized to in situ generate a new series of methyl carbon-bonded cobalt(III) porphyrins with the same pi-extending or highly electron-withdrawing substituents as the initial Co(II) derivatives. Carbon 212-218 mitochondrially encoded cytochrome c oxidase I Homo sapiens 42-47 31824950-5 2019 Similarly, hES cells require methionine (Met) to maintain the Met-SAM (S-adenosyl methionine) cycle of 1-carbon metabolism also for H3K4me3 formation. Carbon 103-111 ribosome binding protein 1 Homo sapiens 11-14 31824950-8 2019 Furthermore, since ES cells are derived from their progenitor cells in preimplantation blastocysts, they serve as models of 1-carbon metabolism in these precursors of all mammalian tissues and organs. Carbon 124-132 ribosome binding protein 1 Homo sapiens 19-21 31824950-10 2019 These 1-carbon metabolism challenges result in altered epigenetic DNA and histone modifications in ES progenitor cells and the tissues and organs to which they develop. Carbon 6-14 ribosome binding protein 1 Homo sapiens 99-101 31756921-3 2019 Four major classes of enzymes that attenuate TCR signaling include E3 ubiquitin kinases such as the Casitas B-lineage lymphoma proteins (Cbl-b and c-Cbl), and Itchy (Itch), inhibitory tyrosine phosphatases, such as Src homology region 2 domain-containing phosphatases (SHP-1 and SHP-2), inhibitory protein kinases, such as C-terminal Src kinase (Csk), and inhibitory lipid kinases such as Src homology 2 (SH2) domain-containing inositol polyphosphate 5-phosphatase (SHIP) and Diacylglycerol kinases (DGKs). Carbon 46-47 Cbl proto-oncogene B Homo sapiens 137-142 31756921-3 2019 Four major classes of enzymes that attenuate TCR signaling include E3 ubiquitin kinases such as the Casitas B-lineage lymphoma proteins (Cbl-b and c-Cbl), and Itchy (Itch), inhibitory tyrosine phosphatases, such as Src homology region 2 domain-containing phosphatases (SHP-1 and SHP-2), inhibitory protein kinases, such as C-terminal Src kinase (Csk), and inhibitory lipid kinases such as Src homology 2 (SH2) domain-containing inositol polyphosphate 5-phosphatase (SHIP) and Diacylglycerol kinases (DGKs). Carbon 46-47 Cbl proto-oncogene Homo sapiens 147-152 9037103-2 1997 Expression of this gene in cells grown on different media indicated that the UBI4 promoter is more active during growth on respiratory than on fermentable carbon sources but is not subject to appreciable control by nitrogen catabolite repression. Carbon 155-161 ubiquitin Saccharomyces cerevisiae S288C 77-81 8973214-7 1996 Titrations of [13C]heme-labeled OM cytochrome b5 with horse heart cytochrome c were carried out in order to monitor the resonances arising from the heme propionate carbonyl carbons in OM cytochrome b5. Carbon 173-180 cytochrome b5 type A Equus caballus 187-200 31787876-4 2019 Here, we show by deletion analysis that regions required for homomeric interaction of Mover are distributed across the entire molecule, including N-terminal, central and C-terminal regions. Carbon 170-171 tumor protein p63 regulated 1 like Homo sapiens 86-91 31589236-0 2019 A long-life Li-CO2 battery employing a cathode catalyst of cobalt-embedded nitrogen-doped carbon nanotubes derived from a Prussian blue analogue. Carbon 90-96 complement C2 Homo sapiens 15-18 29091852-1 2018 Granular activated carbon (GAC) or magnetite could promote methane production from organic wastes, but their roles in enhancing anaerobic sludge digestion have not been clarified. Carbon 19-25 glutaminase Homo sapiens 27-30 29410815-5 2018 The results show that NPC-1-900/CNTF electrode exhibits an exceptional areal capacitance of 121.5 mF cm-2 compared to that of PC-900/CNTF electrode (22.8 mF cm-2) at 5 mV s-1 in a three-electrode system, indicating that the incorporation of nitrogen is beneficial to the electrochemical properties of nanoporous carbon. Carbon 312-318 NPC intracellular cholesterol transporter 1 Homo sapiens 22-27 8910545-4 1996 Enzyme activity measurements and mRNA analyses showed that ACS1 and ACS2 were both expressed during carbon-limited growth on glucose, ethanol, and acetate in aerobic chemostat cultures. Carbon 100-106 acetate--CoA ligase 1 Saccharomyces cerevisiae S288C 59-63 29352139-5 2018 Glutamine carbon flow through GOT2 is required to create NADPH and to maintain the cellular redox state. Carbon 10-16 glutamic-oxaloacetic transaminase 2 Homo sapiens 30-34 29195134-2 2018 Their highly functionalised carbon skeleton, with fixed chirality at C-2 and C-4, makes them ideal starting materials for use in synthesis. Carbon 28-34 complement C2 Homo sapiens 69-72 29195134-2 2018 Their highly functionalised carbon skeleton, with fixed chirality at C-2 and C-4, makes them ideal starting materials for use in synthesis. Carbon 28-34 complement C4A (Rodgers blood group) Homo sapiens 77-80 31553068-0 2019 C-terminal phosphorylation of latrophilin-1/ADGRL1 affects the interaction between its fragments. Carbon 0-1 adhesion G protein-coupled receptor L1 Homo sapiens 30-43 8910545-4 1996 Enzyme activity measurements and mRNA analyses showed that ACS1 and ACS2 were both expressed during carbon-limited growth on glucose, ethanol, and acetate in aerobic chemostat cultures. Carbon 100-106 acetate--CoA ligase ACS2 Saccharomyces cerevisiae S288C 68-72 31553068-0 2019 C-terminal phosphorylation of latrophilin-1/ADGRL1 affects the interaction between its fragments. Carbon 0-1 adhesion G protein-coupled receptor L1 Homo sapiens 44-50 31553068-2 2019 Autoproteolysis cleaves latrophilin-1 into two parts: the extracellular N-terminal fragment (NTF) and the heptahelical C-terminal fragment (CTF). Carbon 119-120 adhesion G protein-coupled receptor L1 Homo sapiens 24-37 8900132-0 1996 Carbon source regulation of PIS1 gene expression in Saccharomyces cerevisiae involves the MCM1 gene and the two-component regulatory gene, SLN1. Carbon 0-6 histidine kinase Saccharomyces cerevisiae S288C 139-143 28763653-7 2017 The practice of conversion of cropland (maize-wheat rotation system) to forest consequently resulted in an average annual net carbon sequestration of 1813.74kgC ha-1 year-1 in the study. Carbon 126-132 plasma membrane ATPase Triticum aestivum 161-165 8923734-2 1996 Using a STA2-lacZ fusion it was found that: (1) the MIG1 gene is dispensable for the repression of the STA2 gene; (2) there are two components in the carbon-source repression of STA2: HXK2-dependent and HXK2-independent; and (3) the HAP2 gene seems to be involved in repression rather than activation of the STA2 expression. Carbon 150-156 transcription factor MIG1 Saccharomyces cerevisiae S288C 52-56 29259117-5 2017 The largest changes in expression plasticity were observed between fermentable (glucose or galactose) and nonfermentable (glycerol) carbon sources and were caused by mutations located in the RAP1 and GCR1 transcription factor binding sites. Carbon 132-138 transcription regulator GCR1 Saccharomyces cerevisiae S288C 200-204 31400705-6 2019 Moreover, the hydrophobic substituents on carbon play an important role in the IL-5 inhibitory activity of these analogs. Carbon 42-48 interleukin 5 Mus musculus 79-83 31446204-0 2019 Interfacial properties of 3D metallic carbon nanostructures (T6 and T14)-reinforced polymer nanocomposites: A molecular dynamics study. Carbon 38-44 CD27 molecule Homo sapiens 68-71 31446204-1 2019 Herein, the interfacial properties of new three-dimensional (3D) configurations of metallic carbon, namely T6 and T14, incorporated to different polymer matrices (T6 and T14@polymers) are studied using molecular dynamics (MD) simulations. Carbon 92-98 CD27 molecule Homo sapiens 114-117 29326925-0 2017 Photodegradation of Rhodamine B over Biomass-Derived Activated Carbon Supported CdS Nanomaterials under Visible Irradiation. Carbon 63-69 CDP-diacylglycerol synthase 1 Homo sapiens 80-83 8878844-0 1996 A role for glucose-6-phosphate dehydrogenase in short- and long-term regulation of photosynthetic and respiratory carbon and nitrogen metabolism in nitrogen-limited Chlamydomonas reinhardtii. Carbon 114-120 uncharacterized protein Chlamydomonas reinhardtii 11-44 29326925-1 2017 A family of new composite materials was successfully prepared through the deposition of as-synthesized CdS nanomaterials on lotus-seedpod-derived activated carbon (SAC). Carbon 156-162 CDP-diacylglycerol synthase 1 Homo sapiens 103-106 29096064-7 2017 A crystal structure of the AprA MT1-GNAT di-domain with bound Mn2+, malonate, and the methyl donor S-adenosylmethionine (SAM) reveals that the malonyl substrate is a bidentate metal ligand, indicating that the metal acts as a Lewis acid to promote methylation of the malonyl alpha-carbon. Carbon 281-287 metallothionein 1I, pseudogene Homo sapiens 32-35 31404637-3 2019 Human CYP21A2 (steroid 21-hydroxylase) acts on the side-chain attached to C-17 in ring D of a steroid substrate, but the configuration of ring A also plays a prominent role in substrate cognition. Carbon 6-7 cytochrome P450 family 21 subfamily A member 2 Homo sapiens 15-37 8840009-11 1996 As C/C-DP inactivates NOS, our findings raise the possibility that NO effects on C/C-DP constitute a feedback mechanism for regulation of NOS activity. Carbon 3-4 cut-like homeobox 1 Rattus norvegicus 83-87 31325077-7 2019 These data indicate that ZmPEPC in the PEPC-OE rice plants contributes to leaf carbon metabolism in both the light and in the dark. Carbon 79-85 MLO-like protein 4 Zea mays 27-31 29181479-2 2017 In this work, we constructed nanohybrid Ru1@CDs composed of carbon nanodots (CDs) and a phosphorescent Ru(ii) complex (Ru1) for one- and two-photon photodynamic therapy of cancer. Carbon 60-66 Scm like with four mbt domains 1 Homo sapiens 40-43 29182188-2 2017 Here, a multifunctional carbon cloth supported cobalt phosphide (CoP@CC) electrocatalyst was synthesized via a simple electrochemical deposition followed by subsequent phosphorization. Carbon 24-30 caspase recruitment domain family member 16 Homo sapiens 65-68 8670822-3 1996 The (delta)arcA mutant is severely impaired in surviving prolonged periods of exogenous carbon starvation, a phenotype that can be alleviated by overproducing the superoxide dismutase SodA. Carbon 88-94 arginine deiminase Escherichia coli 11-15 28919435-3 2017 Whole horse IgG3 (hoIgG3) was immobilized onto the surface of carbon or gold screen-printed electrodes through a cross-linking solution of glutaraldehyde on a chitosan film. Carbon 62-68 immunoglobulin heavy constant gamma 3 (G3m marker) Homo sapiens 12-16 31657439-2 2019 In cells, release from the C-terminal diaphanous autoregulatory domain (DAD) of FHOD1 stimulates the protein into the active form. Carbon 27-28 formin homology 2 domain containing 1 Homo sapiens 80-85 31657439-4 2019 Here, we show that in contrast with the cytosolic diffused expression of auto-inhibited FHOD1, active FHOD1 by C-terminal truncation was recruited into all three types of actin stress fibers in human osteosarcoma cells. Carbon 111-112 formin homology 2 domain containing 1 Homo sapiens 102-107 8757740-2 1996 Cdc25 is a GTP-exchange protein involved in activating RAS in response to fermentable carbon sources. Carbon 86-92 Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C 0-5 31749617-0 2019 Vitamin K1 As A Potential Molecule For Reducing Single-Walled Carbon Nanotubes-Stimulated alpha-Synuclein Structural Changes And Cytotoxicity. Carbon 62-68 synuclein alpha Homo sapiens 90-105 31844685-0 2019 SIX3 and SIX6 interact with GEMININ via C-terminal regions. Carbon 40-41 geminin DNA replication inhibitor Homo sapiens 28-35 31844685-6 2019 The presence of the C-terminal regions of SIX3 and SIX6 proteins, but not their SIX domains or homeodomains as previously thought, were required for interaction with GEMININ. Carbon 20-21 geminin DNA replication inhibitor Homo sapiens 166-173 31844685-7 2019 Interestingly, the disordered C- and N- terminal regions of GEMININ were involved in binding to SIX3/SIX6. Carbon 30-31 geminin DNA replication inhibitor Homo sapiens 60-67 31624245-3 2019 Integrating anti-MYCN ChIP-seq and gene expression profiles of neuroblastoma patients revealed the metabolic enzymes, MTHFD2 and PAICS, required for one-carbon metabolism and purine biosynthesis were concomitantly upregulated, which were more susceptible to metastatic neuroblastoma. Carbon 153-159 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 17-21 28985603-4 2017 The hydroxyl functionalized ionic liquids which exhibited the best enzymatic properities was selected to investigate the effects of different carbon chain length on the enzymatic properties of immobilized CALB. Carbon 142-148 calbindin 1 Homo sapiens 205-209 29321350-8 2017 The restoration of one-carbon homeostasis by SHMT1 C1420T or increased flux of folate towards remethylation due to TYMS 5"-UTR 28 bp tandem repeat or nonvegetarian diet can lower homocysteine levels. Carbon 23-29 serine hydroxymethyltransferase 1 Homo sapiens 45-50 29238697-2 2017 There is increasing evidence that ATM also plays an important role in other cellular processes, including carbon metabolism. Carbon 106-112 ATM serine/threonine kinase Homo sapiens 34-37 8668134-4 1996 When induced in the stationary phase of growth in rich medium or during carbon starvation, transcription of spvR in S. typhimurium is driven by a single promoter (spvRp1) and initiates 17 nucleotides upstream of the spvR start codon. Carbon 72-78 Salmonella plasmid virulence lysR family regulator Salmonella enterica subsp. enterica serovar Typhimurium 108-112 29238697-4 2017 A number of recent studies report a non-canonical role for ATM in the regulation of carbon metabolism. Carbon 84-90 ATM serine/threonine kinase Homo sapiens 59-62 29238697-5 2017 This review highlights what is currently known about ATM"s regulation of carbon metabolism, the implication of these pathways in cancer, and the development of ATM inhibitors as therapeutic strategies for cancer. Carbon 73-79 ATM serine/threonine kinase Homo sapiens 53-56 31594538-5 2019 Furthermore, we confirmed that the LSH-PKM2 interaction occurred at the intersubunit interface region of the PKM2 C-terminal region and the coiled-coil domains (CC) and ATP-binding domains of LSH, and this interaction regulated p53-mediated transactivation in cis in lipid metabolism, especially lipid catabolism. Carbon 114-115 pyruvate kinase M1/2 Homo sapiens 39-43 31594538-5 2019 Furthermore, we confirmed that the LSH-PKM2 interaction occurred at the intersubunit interface region of the PKM2 C-terminal region and the coiled-coil domains (CC) and ATP-binding domains of LSH, and this interaction regulated p53-mediated transactivation in cis in lipid metabolism, especially lipid catabolism. Carbon 114-115 pyruvate kinase M1/2 Homo sapiens 109-113 8657561-6 1996 Gel mobility shift analysis and in vitro DNase I footprinting have shown that proteins bind specifically to two downstream repressor sequences (DRS1 located from +140 to +163 and DRS2 located between +231 and +251) that influence the rate of HXK2 transcription when ethanol is used as carbon source by Saccharomyces cerevisiae. Carbon 285-291 aminophospholipid-translocating P4-type ATPase DRS2 Saccharomyces cerevisiae S288C 179-183 31854799-13 2019 EC2 (elemental carbon which was measured at temperatures of 700C) was the highest carbon content of diesel vehicles under China III and China IV emission standards, which can be used in the identification of diesel vehicles in source apportionment studies. Carbon 15-21 transcription factor 15 Homo sapiens 0-3 31854799-13 2019 EC2 (elemental carbon which was measured at temperatures of 700C) was the highest carbon content of diesel vehicles under China III and China IV emission standards, which can be used in the identification of diesel vehicles in source apportionment studies. Carbon 82-88 transcription factor 15 Homo sapiens 0-3 29058411-2 2017 CCPEimBr was adopted as the functional monomer to prepare a molecularly imprinted polymerized ionic liquid hydrogel film on a glassy carbon electrode surface for human epididymis protein 4 (HE4) sensing. Carbon 133-139 WAP four-disulfide core domain 2 Homo sapiens 190-193 29064705-1 2017 We present an experimental study on the near-field light-matter interaction by tip-enhanced Raman scattering (TERS) with polarized light in three different materials: germanium-doped gallium nitride (GaN), graphene, and carbon nanotubes. Carbon 220-226 TOR signaling pathway regulator Homo sapiens 79-82 31237436-4 2019 Consequently, we outline a Mars exploration strategy that targets subsurface life and scales spatially, focusing initially on identifying rocks with evidence for groundwater flow and low-temperature mineralization, then identifying redox and permeability interfaces preserved within rock outcrops, and finally focusing on finding minerals associated with redox reactions and associated traces of carbon and diagnostic chemical and isotopic biosignatures. Carbon 396-402 methionyl-tRNA synthetase 1 Homo sapiens 27-31 8621527-3 1996 For both catalases the heme d is rotated 180 degrees about the axis defined by the alpha-gamma-meso carbon atoms, with respect to the orientation found for heme b in beef liver catalase. Carbon 100-106 catalase Bos taurus 9-17 31581480-11 2019 Deletion of the tricellulin C-terminal amino acids prevented binding to lipolysis-stimulated lipoprotein receptor (LSR)/angulin-1 and thus should impair specific localization of tricellulin to tTJs. Carbon 28-29 lipolysis stimulated lipoprotein receptor Homo sapiens 72-113 31581480-11 2019 Deletion of the tricellulin C-terminal amino acids prevented binding to lipolysis-stimulated lipoprotein receptor (LSR)/angulin-1 and thus should impair specific localization of tricellulin to tTJs. Carbon 28-29 lipolysis stimulated lipoprotein receptor Homo sapiens 115-118 28756318-2 2017 Versatile counter electrodes using this carbon sphere catalyst on different substrates of fluorine-doped tin oxide (FTO) glass, indium-doped tin oxide polyethylenena phthalate (ITO-PEN), and Ti foil are fabricated for dye-sensitized solar cell (DSC). Carbon 40-46 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 181-184 28756318-4 2017 With cobalt electrolyte, the DSC using carbon sphere counter electrodes based on FTO glass, ITO-PEN, and Ti substrates yield high power conversion efficiency values of 8.57%, 6.66%, and 9.10%, respectively. Carbon 39-45 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 96-99 29057400-2 2017 In this communication, we report a novel structure consisting of a Cu3P-CoP hybrid nanowire array supported on carbon cloth (Cu3P-CoP/CC) as a superior HER electrocatalyst in acidic media. Carbon 111-117 caspase recruitment domain family member 16 Homo sapiens 72-75 31483287-2 2019 We have identified that endogenous type I IFN controls the cellular citrate/alpha-ketoglutarate ratio and inhibits expression and activity of isocitrate dehydrogenase (IDH); and, via 13C-labeling studies, demonstrated that autocrine type I IFN controls carbon flow through IDH in LPS-activated macrophages. Carbon 253-259 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 168-171 29057400-2 2017 In this communication, we report a novel structure consisting of a Cu3P-CoP hybrid nanowire array supported on carbon cloth (Cu3P-CoP/CC) as a superior HER electrocatalyst in acidic media. Carbon 111-117 caspase recruitment domain family member 16 Homo sapiens 130-133 8784957-1 1996 We show that the spinning side-bands of protonated and non-protonated carbon atoms can be well separated by means of the standard SCP and LCPD experiments at a relatively slow sample spinning rate or at high magnetic field. Carbon 70-76 urocortin 3 Homo sapiens 130-133 28535471-4 2017 The carbonized PANI@GO hybrid was used to modify a glassy carbon electrode (GCE) based on GOx, resulting in efficient direct electron transfer (DET) and excellent bio-catalytic performance. Carbon 4-10 aminomethyltransferase Homo sapiens 76-79 31570513-4 2019 We discovered that HELZ associates with various mRNA decay factors, including components of the carbon catabolite repressor 4-negative on TATA box (CCR4-NOT) deadenylase complex in human and Drosophila melanogaster cells. Carbon 96-102 helicase with zinc finger Homo sapiens 19-23 31681792-3 2019 In order to better understand the domain dynamics comparative Molecular Dynamics (MD) simulations of a sub-structure of Hsp90, the dimer formed by the middle (M) and C-terminal domain (C), were performed. Carbon 185-186 Hsp90 family chaperone HSP82 Saccharomyces cerevisiae S288C 120-125 31921542-1 2020 The synthesis of morphology-controlled carbon-coated nanostructured LiFePO4 (LFP/Carbon) cathode materials by surfactant-assisted hydrothermal method using block copolymers is reported. Carbon 39-45 lamin A/C Homo sapiens 77-80 12226231-3 1996 In microsomes from Cuphea lanceolata, a plant that accumulates fatty acids with 10 carbons and no double bonds (10:0) in its oil, the diacylglycerol acyltransferase exhibited 4-fold higher activity with 10:0/10:0 molecular species of diacylglycerol than with molecular species containing 18-carbon fatty acids. Carbon 83-90 diacylglycerol O-acyltransferase 1 Ricinus communis 134-164 28751199-4 2017 Appropriate manipulation of the anomeric carbon in the furanose fused pyrrolidine ring skeleton afforded alpha-geminal disubstituted pyrrolidine iminosugars 3a-c and C-4 fluoro derivatives 4a-c. Carbon 41-47 complement C4A (Rodgers blood group) Homo sapiens 166-169 31548257-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2 and EXO70F1. Carbon 22-23 RPM1 interacting protein 4 Arabidopsis thaliana 47-53 8729243-2 1996 PQQ-dependent methanol dehydrogenase (EC 1.1.99.8) was immobilized onto the surface of a carbon paste electrode by the cross-linking method and the electrode was covered with a porous polycarbonate membrane. Carbon 89-95 MEXAM1_RS21720 Methylobacterium extorquens AM1 23-36 31548257-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2 and EXO70F1. Carbon 22-23 exocyst subunit exo70 family protein B1 Arabidopsis thaliana 90-97 31548257-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2 and EXO70F1. Carbon 22-23 exocyst subunit exo70 family protein E2 Arabidopsis thaliana 108-115 31667125-3 2019 The other is proposed to be near the C-terminus where multiple transmembrane domains promote hydrophobic interactions between two ACAT1 subunits. Carbon 37-38 acetyl-CoA acetyltransferase 1 Homo sapiens 130-135 28622645-1 2017 The soil sorption coefficient normalized to the organic carbon content (Koc) is a physicochemical parameter used in environmental risk assessments and in determining the final fate of chemicals released into the environment. Carbon 56-62 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 72-75 28756863-5 2017 The electrocatalytic current response of proline dehydrogenase entrapped in a magnetic mesoporous silica nanomaterial toward oxidation of L-proline was maintained in the analytical solution temperature up to 70 C. The entrapped proline dehydrogenase was casted onto a polycysteine-modified glassy carbon electrode. Carbon 297-303 proline dehydrogenase Mus musculus 41-62 28756863-5 2017 The electrocatalytic current response of proline dehydrogenase entrapped in a magnetic mesoporous silica nanomaterial toward oxidation of L-proline was maintained in the analytical solution temperature up to 70 C. The entrapped proline dehydrogenase was casted onto a polycysteine-modified glassy carbon electrode. Carbon 297-303 proline dehydrogenase Mus musculus 228-249 8777139-4 1996 Treating hCG with sodium periodate to remove two carbon atoms from NeuAc or quantitatively removing NeuAc from hCG reduced its biological activity by 36% and 50%, respectively. Carbon 49-55 chorionic gonadotropin subunit beta 5 Homo sapiens 9-12 29081462-4 2017 We investigated whether the carbon and nitrogen stable isotope ratios in hair are associated with serum leptin levels. Carbon 28-34 leptin Homo sapiens 104-110 31167177-4 2019 RBS/C reveals the non-linear response of damage distribution with Ar ion fluence. Carbon 4-5 establishment of sister chromatid cohesion N-acetyltransferase 2 Homo sapiens 0-3 8777139-7 1996 These results suggest that several structural aspects of NeuAc including carbon side chain, an intact ring structure, and the position of NeuAc relative to other carbohydrate residues are important for full biological activity of hCG. Carbon 73-79 chorionic gonadotropin subunit beta 5 Homo sapiens 230-233 31420217-2 2019 Here, we find that lipopolysaccharide (LPS) activates the pentose phosphate pathway, the serine synthesis pathway, and one-carbon metabolism, the synergism of which drives epigenetic reprogramming for interleukin-1beta (IL-1beta) expression. Carbon 123-129 interleukin 1 alpha Homo sapiens 220-228 8924604-9 1996 From these homology modeling and docking data, the difference in stereoselectivity between GST 3-3 and GST 4-4 for the R- and S-configured carbons of the oxirane moiety could be rationalized. Carbon 139-146 glutathione S-transferase mu 2 Rattus norvegicus 103-110 31500170-0 2019 Carbon Nanoparticles Inhibit Alpha-Glucosidase Activity and Induce a Hypoglycemic Effect in Diabetic Mice. Carbon 0-6 sucrase isomaltase (alpha-glucosidase) Mus musculus 29-46 28973985-2 2017 Exploiting a nutritional B-vitamin deficiency paradigm, we have previously shown that PSEN1 and BACE1 activity is modulated by one-carbon metabolism, leading to increased amyloid production. Carbon 131-137 presenilin 1 Mus musculus 86-91 28973985-2 2017 Exploiting a nutritional B-vitamin deficiency paradigm, we have previously shown that PSEN1 and BACE1 activity is modulated by one-carbon metabolism, leading to increased amyloid production. Carbon 131-137 beta-site APP cleaving enzyme 1 Mus musculus 96-101 28720494-3 2017 However, we demonstrate here that Bds1 acts on primary alkyl sulfates (of 6-12 carbon atoms) but not the aryl sulfates p-nitrophenyl sulfate and p-nitrocatechol sulfate. Carbon 79-85 sulfuric ester hydrolase Saccharomyces cerevisiae S288C 34-38 28720494-5 2017 We show that Bds1 shares a catalytic mechanism with SdsA1 in which the carbon atom of the sulfate ester is the subject of nucleophilic attack, rather than the sulfur atom, resulting in C-O bond lysis. Carbon 71-77 sulfuric ester hydrolase Saccharomyces cerevisiae S288C 13-17 31298961-4 2019 Materials and Methods: The effect of C-82, an active metabolite of PRI-724, on the expression of TGF-beta1 and alpha-smooth muscle actin (SMA) was examined on fibroblasts and macrophages. Carbon 37-38 immunoglobulin mu binding protein 2 Mus musculus 111-136 31298961-4 2019 Materials and Methods: The effect of C-82, an active metabolite of PRI-724, on the expression of TGF-beta1 and alpha-smooth muscle actin (SMA) was examined on fibroblasts and macrophages. Carbon 37-38 immunoglobulin mu binding protein 2 Mus musculus 138-141 8526867-2 1995 This enzyme, designated AFAR, displays high activity towards dicarbonyl-containing compounds with ketone groups on adjacent carbon atoms; 9,10-phenanthrenequinone, acenaphthenequinone and camphorquinone were found to be good substrates. Carbon 63-69 aldo-keto reductase family 7 member A3 Rattus norvegicus 24-28 31426146-0 2019 Anthropogenic carbon as a basal resource in the benthic food webs in the Neva Estuary (Baltic Sea). Carbon 14-20 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 94-97 31480345-0 2019 Land Use Eco-Efficiency and Its Convergence Characteristics Under the Constraint of Carbon Emissions in China. Carbon 84-90 ciliogenesis associated kinase 1 Homo sapiens 9-12 28570877-1 2017 In this research was immobilized anthraquinone-2-sulfonate (AQS) on granular activated carbon (GAC) to evaluate its capacity to reduce congo red (CR) in batch reactor and continuous UASB reactors. Carbon 87-93 glutaminase Homo sapiens 95-98 28734603-2 2017 In this work, a dynamic headspace needle-trap device (D-HS-NTD) with a ZIF-8-derived nanoporous carbon (ZIF-8-NPC) as the adsorbent was developed for the extraction of some VOCs in different pen inks prior to GC-MS detection. Carbon 96-102 NPC intracellular cholesterol transporter 1 Homo sapiens 104-113 7592476-4 1995 In addition, both mutants are partially defective in CYB2 expression when grown on nonfermentable carbon sources, indicating a positive regulatory role as well. Carbon 98-104 L-lactate dehydrogenase (cytochrome) Saccharomyces cerevisiae S288C 53-57 28715197-1 2017 The effects of electrochemical preconditioning of P-55 pitch-based carbon-fiber microelectrodes were quantitatively examined in this study. Carbon 67-73 H3 histone pseudogene 44 Homo sapiens 50-54 7592476-7 1995 This mutant also has increased SUC2 expression on nonrepressing carbon sources. Carbon 64-70 beta-fructofuranosidase SUC2 Saccharomyces cerevisiae S288C 31-35 7578261-1 1995 In Saccharomyces cerevisiae induction of the FOX3 gene, encoding peroxisomal 3-oxoacyl-CoA thiolase, by growth on oleate as sole carbon source, is exerted via the cis-acting DNA element designated oleate response element (ORE) (Einerhand et al. Carbon 129-135 acetyl-CoA C-acyltransferase Saccharomyces cerevisiae S288C 45-49 28580665-2 2017 In this work, fluorescence carbon quantum dots coordinated by Ce3+ ions (CQDCe) have been synthesized and exploited as building blocks to generate a series of hierarchical structures through the ionic self-assembly of CQDCe and biomolecules, namely DNA, myoglobin (Mb), and hyaluronic acid (HA). Carbon 27-33 myoglobin Homo sapiens 254-263 31467345-0 2019 A major sea-level drop briefly precedes the Toarcian oceanic anoxic event: implication for Early Jurassic climate and carbon cycle. Carbon 118-124 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 8-11 7588797-9 1995 The effects of overproducing UGPase on the cell metabolism and morphology were carbon-source dependent. Carbon 79-85 UTP--glucose-1-phosphate uridylyltransferase Solanum tuberosum 29-35 31456042-14 2019 Graphical abstract Schematic representation of the preparation of carbon sheets similar to graphene oxide from onion sheaths after pyrolysis at 800 C. The prepared carbon sheet-MnFe2O4 composite shows excellent arsenic sorption and preconcentration down to the pg mL-1 concentration. Carbon 66-72 L1 cell adhesion molecule Mus musculus 265-269 31456042-14 2019 Graphical abstract Schematic representation of the preparation of carbon sheets similar to graphene oxide from onion sheaths after pyrolysis at 800 C. The prepared carbon sheet-MnFe2O4 composite shows excellent arsenic sorption and preconcentration down to the pg mL-1 concentration. Carbon 165-171 L1 cell adhesion molecule Mus musculus 265-269 31438886-12 2019 Furthermore, we have noticed that after carbon ion irradiation, circRNA CBL.11 was increased in CRC cells and could function as a competing endogenous RNA (ceRNA) to regulate YWHAE expression by sponging miR-6778-5p, resulting in regulation the proliferation of CRC cells. Carbon 40-46 Cbl proto-oncogene Homo sapiens 72-75 31438886-13 2019 CONCLUSION: CircRNA CBL.11 may play an important role in improving the efficacy of carbon ion RT against CRC. Carbon 83-89 Cbl proto-oncogene Homo sapiens 20-23 28489250-2 2017 Sea-level rise and other climate-change-induced disturbances threaten coastal wetland sustainability and carbon storage capacity. Carbon 105-111 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 0-3 29404047-1 2017 An electrochemically pretreated silver macroporous (Ag MP) multiwalled carbon nanotube modified glassy carbon electrode (PAN-Ag MP-MWCNT-GCE) was fabricated for the selective determination of an anti-hyperlipidimic drug, pitavastatin (PST). Carbon 71-77 aminomethyltransferase Homo sapiens 137-140 29404047-1 2017 An electrochemically pretreated silver macroporous (Ag MP) multiwalled carbon nanotube modified glassy carbon electrode (PAN-Ag MP-MWCNT-GCE) was fabricated for the selective determination of an anti-hyperlipidimic drug, pitavastatin (PST). Carbon 103-109 aminomethyltransferase Homo sapiens 137-140 31310099-5 2019 The incubation of the probes with the sample solutions containing the target CTCs can lead to the efficient separation of the CTCs and result in the generation of two distinct voltammetric peaks on a screen-printed carbon electrode, whose potentials and current intensities, respectively, reflect the identity and number of CTCs for the multiplexed detection of the Ramos and CCRF-CEM cells with detection limits down to 4 and 3 cells mL-1. Carbon 215-221 L1 cell adhesion molecule Mus musculus 435-439 7664636-1 1995 1 alpha, 25-Dihydroxyvitamin D3 [1 alpha, 25-(OH)2D3], the hormonal form of vitamin D3, is further metabolized in the kidney and intestine through the carbon 24 (C-24) oxidation pathway initiated by C-24 hydroxylation, and the carbon 23 (C-23) oxidation pathway initiated by C-23 hydroxylation. Carbon 151-157 nucleolin Homo sapiens 238-242 31391321-4 2019 Mutations in EGFR or PTEN generated distinct CAD phosphorylation patterns to activate carbon influx through pyrimidine synthesis. Carbon 86-92 phosphatase and tensin homolog Homo sapiens 21-25 31337681-5 2019 When S. cerevisiae grows on a nonfermentable carbon source, its gluconeogenic enzymes Fbp1, Icl1, Mdh2, and Pck1 are expressed and long-lived. Carbon 45-51 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 98-102 31337681-5 2019 When S. cerevisiae grows on a nonfermentable carbon source, its gluconeogenic enzymes Fbp1, Icl1, Mdh2, and Pck1 are expressed and long-lived. Carbon 45-51 phosphoenolpyruvate carboxykinase PCK1 Saccharomyces cerevisiae S288C 108-112 28574606-0 2017 Sfp1 and Rtg3 reciprocally modulate carbon source-conditional stress adaptation in the pathogenic yeast Candida albicans. Carbon 36-42 zinc-coordinating transcription factor SFP1 Saccharomyces cerevisiae S288C 0-4 28574606-0 2017 Sfp1 and Rtg3 reciprocally modulate carbon source-conditional stress adaptation in the pathogenic yeast Candida albicans. Carbon 36-42 Rtg3p Saccharomyces cerevisiae S288C 9-13 28574606-6 2017 In particular, two transcription factors (Sfp1 and Rtg3) promote stress resistance in a reciprocal, carbon source-conditional manner. Carbon 100-106 zinc-coordinating transcription factor SFP1 Saccharomyces cerevisiae S288C 42-46 28574606-6 2017 In particular, two transcription factors (Sfp1 and Rtg3) promote stress resistance in a reciprocal, carbon source-conditional manner. Carbon 100-106 Rtg3p Saccharomyces cerevisiae S288C 51-55 28574606-8 2017 Rtg3 and Sfp1 regulate the expression of key stress genes such as CTA4, CAP1 and HOG1 in a carbon source-dependent manner. Carbon 91-97 Rtg3p Saccharomyces cerevisiae S288C 0-4 28574606-8 2017 Rtg3 and Sfp1 regulate the expression of key stress genes such as CTA4, CAP1 and HOG1 in a carbon source-dependent manner. Carbon 91-97 zinc-coordinating transcription factor SFP1 Saccharomyces cerevisiae S288C 9-13 7664636-1 1995 1 alpha, 25-Dihydroxyvitamin D3 [1 alpha, 25-(OH)2D3], the hormonal form of vitamin D3, is further metabolized in the kidney and intestine through the carbon 24 (C-24) oxidation pathway initiated by C-24 hydroxylation, and the carbon 23 (C-23) oxidation pathway initiated by C-23 hydroxylation. Carbon 151-157 nucleolin Homo sapiens 275-279 7664636-1 1995 1 alpha, 25-Dihydroxyvitamin D3 [1 alpha, 25-(OH)2D3], the hormonal form of vitamin D3, is further metabolized in the kidney and intestine through the carbon 24 (C-24) oxidation pathway initiated by C-24 hydroxylation, and the carbon 23 (C-23) oxidation pathway initiated by C-23 hydroxylation. Carbon 162-163 nucleolin Homo sapiens 238-242 28762673-3 2017 Serine hydroxymethyl transferase (SHMT1) provides one-carbon units necessary for embryogenesis and defects in one-carbon production result in specific pathological conditions during pregnancy. Carbon 54-60 serine hydroxymethyltransferase 1 Homo sapiens 34-39 28762673-3 2017 Serine hydroxymethyl transferase (SHMT1) provides one-carbon units necessary for embryogenesis and defects in one-carbon production result in specific pathological conditions during pregnancy. Carbon 114-120 serine hydroxymethyltransferase 1 Homo sapiens 34-39 31075639-7 2019 These measurements also verified the presence of [-CCl2-] groups and chlorine atoms on terminal carbons in highly chlorinated (>59% Cl) mixtures. Carbon 96-103 C-C motif chemokine ligand 2 Homo sapiens 51-55 7664636-1 1995 1 alpha, 25-Dihydroxyvitamin D3 [1 alpha, 25-(OH)2D3], the hormonal form of vitamin D3, is further metabolized in the kidney and intestine through the carbon 24 (C-24) oxidation pathway initiated by C-24 hydroxylation, and the carbon 23 (C-23) oxidation pathway initiated by C-23 hydroxylation. Carbon 162-163 nucleolin Homo sapiens 275-279 8948466-7 1995 1H-NMR spectroscopy of 10-HCO-H2folate (in 2H2O; 300 MHz) suggested a pure compound and gave resonances for one formyl group proton, two protons on C-7 and C-9, and no evidence for a C-6 proton, which is consistent with the structure proposed. Carbon 27-28 complement C6 Gallus gallus 183-186 31088832-0 2019 Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway. Carbon 77-83 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 27-31 31088832-3 2019 Here we report that neuroblastoma cells with MYCN amplification show increased transcriptional activation of the serine-glycine-one-carbon (SGOC) biosynthetic pathway and an increased dependence on this pathway for supplying glucose-derived carbon for serine and glycine synthesis. Carbon 132-138 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 45-49 27671197-0 2017 Toward sensitive immuno-based detection of tau protein by surface plasmon resonance coupled to carbon nanostructures as signal amplifiers. Carbon 95-101 microtubule associated protein tau Homo sapiens 43-46 28740502-8 2017 Carbon starvation enhanced the level of phosphorylated YFP-ATG1a in the KIN10-OE lines compared to that of wild type. Carbon 0-6 SNF1 kinase homolog 10 Arabidopsis thaliana 72-77 31088832-3 2019 Here we report that neuroblastoma cells with MYCN amplification show increased transcriptional activation of the serine-glycine-one-carbon (SGOC) biosynthetic pathway and an increased dependence on this pathway for supplying glucose-derived carbon for serine and glycine synthesis. Carbon 241-247 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 45-49 7760058-6 1995 From the C-3/C-4 labeling ratios in glutamine and glutamate and from the corresponding C-3/C-2 labeling ratio in GABA obtained with [2-13C]acetate, it was concluded that the carbon skeleton of glutamine to some extent was passed through TCA cycles before glutamate and GABA were formed. Carbon 174-180 complement component 3 Mus musculus 9-12 31371280-0 2019 Serine-Glycine-One-Carbon Metabolism: The Hidden Achilles Heel of MYCN-Amplified Neuroblastoma? Carbon 19-25 MYCN proto-oncogene, bHLH transcription factor Homo sapiens 66-70 7760058-6 1995 From the C-3/C-4 labeling ratios in glutamine and glutamate and from the corresponding C-3/C-2 labeling ratio in GABA obtained with [2-13C]acetate, it was concluded that the carbon skeleton of glutamine to some extent was passed through TCA cycles before glutamate and GABA were formed. Carbon 174-180 complement component 3 Mus musculus 87-90 7750560-0 1995 Substrate interactions in cytochrome P-450: correlation between carbon-13 nuclear magnetic resonance chemical shifts and C-O vibrational frequencies. Carbon 64-70 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 37-42 31158793-4 2019 REDOR-filtering of carbon correlation spectra removes signals from rigid backbone carbons and retains signals from backbone carbons with ms-timescale dynamics that would be missing in dipolar-driven NCA/NCO spectra. Carbon 19-25 CEA cell adhesion molecule 6 Homo sapiens 199-202 7727418-2 1995 Yeast strains with null alleles of either of these two genes (delta rtg1, delta rtg2) cannot grow on acetate as the sole carbon source and are auxotrophic for glutamate and aspartate. Carbon 121-127 Rtg2p Saccharomyces cerevisiae S288C 80-84 31115151-2 2019 The carbon catabolite repressor 4 (CCR4)-associated factor 1 (CAF1) component of the CCR4-NOT deadenylase complex plays an essential role in mRNA deadenylation in most eukaryotes. Carbon 4-10 CCR4-NOT core DEDD family RNase subunit POP2 Saccharomyces cerevisiae S288C 62-66 31264416-5 2019 Coefficients in the model were determined using a data set including the organic carbon-water partition coefficient (KOC) of four polycyclic aromatic hydrocarbons (PAHs) sorption to 10 NOM samples collected from surface waters. Carbon 81-87 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 117-120 7867719-1 1995 Cell proliferation arrest at 37 degrees C (restrictive temperature) of the cell division cycle (cdc) mutants of Saccharomyces cerevisiae cdc28, cdc35, cdc19, cdc21, and cdc17 was correlated with carbon and energy uncoupling. Carbon 195-201 DNA-directed DNA polymerase alpha catalytic subunit POL1 Saccharomyces cerevisiae S288C 169-174 15091518-7 1995 Comparable affinity of culture MM1 for both methane and C(11)LAS ( [Formula: see text], respectively), and more than four times higher maximum transformation rate for methane than for C(11)LAS ( [Formula: see text] (dry weight) cells day(-1), respectively), were determined. Carbon 0-1 prefoldin subunit 5 Homo sapiens 31-34 31248254-8 2019 In ethenolysis, Ru-1 is 5x more robust to standard-grade (99.9%) C2H4 than the top-performing catalyst, probably reflecting steric protection at the quaternary CAAC carbon. Carbon 165-171 Scm like with four mbt domains 1 Homo sapiens 16-20 31379988-7 2019 We have previously shown using a yeast model that vanillic acid (VA) can bypass mutations of COQ6, a monooxygenase required for the hydroxylation of the C5 carbon of the ring. Carbon 156-162 putative N,N-dimethylaniline monooxygenase COQ6 Saccharomyces cerevisiae S288C 93-97 15091518-7 1995 Comparable affinity of culture MM1 for both methane and C(11)LAS ( [Formula: see text], respectively), and more than four times higher maximum transformation rate for methane than for C(11)LAS ( [Formula: see text] (dry weight) cells day(-1), respectively), were determined. Carbon 56-57 prefoldin subunit 5 Homo sapiens 31-34 8584672-3 1995 Both lysyl oxidase and SSAO catalyze the oxidation of tyramine with removal of the pro-S hydrogen from C-1 of this substrate. Carbon 103-104 amine oxidase copper containing 3 Homo sapiens 23-27 31001886-0 2019 Temperature and phosphorus interacts in controlling the picoplankton carbon flux in the Adriatic Sea: an experimental versus field study. Carbon 69-75 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 97-100 31001886-3 2019 Therefore, in the global warming scenario, an increase of the picoplankton carbon flux towards higher trophic levels can be expected in the Adriatic Sea, particularly under unlimited phosphorus conditions. Carbon 75-81 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 149-152 8584672-4 1995 The copper amine oxidase enzymes that react with abstraction of the pro-S hydrogen from C-1 of substrates do not exhibit a solvent exchange pathway. Carbon 88-89 amine oxidase copper containing 3 Homo sapiens 4-24 30693532-8 2019 It also provides a description of folate-mediated one-carbon metabolism and its intersection with Cbl at the methionine cycle. Carbon 54-60 Cbl proto-oncogene Homo sapiens 98-101 8089172-7 1994 Cells disrupted in the MMM1 gene are inviable when grown on nonfermentable carbon sources and show abnormal mitochondrial morphology at all temperatures. Carbon 75-81 ERMES complex subunit MMM1 Saccharomyces cerevisiae S288C 23-27 8089622-7 1994 These radical-induced reductions proceed via dissociative electron capture and, under cleavage of the C-halogen bond, yield C-6 carbon-centered radicals. Carbon 128-134 complement C6 Homo sapiens 124-127 30954023-7 2019 We stimulated HGECs with ultrapure LPS (TLR4 ligand) and Poly I:C (TLR3 ligand) for 24 h and supernatant was used to determine IFN-beta secretion. Carbon 17-18 toll like receptor 4 Homo sapiens 40-44 7848561-5 1994 In these complexes, the chromophore has its concave side in the major groove, its long axis nearly colinear with the mean long axis of the two base pairs of the intercalation site, and a bidentate H-bonded configuration occurs which involves the C = O and NH groups of the D-Asn side chain and HN6 and N7 (resp.) of the adenine base upstream. Carbon 246-247 MT-RNR2 like 6 (pseudogene) Homo sapiens 294-297 31217306-2 2019 Snf4 is required to release the N-terminal catalytic domain of Snf1 from autoinhibition by the C-terminal regulatory domain, and snf4Delta mutants cannot grow on carbon sources other than glucose. Carbon 162-168 AMP-activated serine/threonine-protein kinase regulatory subunit SNF4 Saccharomyces cerevisiae S288C 0-4 30926003-4 2019 Under optimized experimental conditions, the electroanalytical investigation confirmed that CS-PC BPE modified glassy carbon electrode (CS-PC BPE/GCE) was found to sense MNZ and MTZ in the nanomolar range. Carbon 118-124 aminomethyltransferase Homo sapiens 136-149 8119960-2 1994 The promoter region of the TDH3 gene is known to exhibit high transcriptional activity regardless of the fermentability of the carbon source and has been widely utilized to synthesize heterologous gene products in S. cerevisiae. Carbon 127-133 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3 Saccharomyces cerevisiae S288C 27-31 31197573-0 2019 Intracellular fluorometric determination of microRNA-21 by using a switch-on nanoprobe composed of carbon nanotubes and gold nanoclusters. Carbon 99-105 microRNA 21 Homo sapiens 44-55 8119960-13 1994 We therefore concluded that constitutive transcription by the TDH3 promoter is sustained by two promoter elements and that the switch between them might be controlled by the nonfermentable carbon source-inducible GPEB. Carbon 189-195 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3 Saccharomyces cerevisiae S288C 62-66 8269960-3 1993 Deletion of the gene encoding PPQ1 reduces cell growth on several carbon sources, and lowers cell density in the stationary phase. Carbon 66-72 protein-serine/threonine phosphatase Saccharomyces cerevisiae S288C 30-34 8226724-2 1993 Gal4 transcriptional activator protein binds to the two consensus UAS sites whether GAL2 expression is induced, uninduced, or repressed by growth with different carbon sources. Carbon 161-167 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 0-4 8272967-0 1993 A carbon fiber implant to aid interbody lumbar fusion. Carbon 2-8 activation induced cytidine deaminase Homo sapiens 26-29 8272967-9 1993 The carbon implant achieved successful fusion in 6/6 (100%) of followed patients treated for a failed ETO allograft interbody fusion. Carbon 4-10 RUNX1 partner transcriptional co-repressor 1 Homo sapiens 102-105 7916689-3 1993 The isolated POT1 clones hybridized to a 1.4 kb RNA species, which was induced approximately 30-fold when oleate was the carbon source. Carbon 121-127 acetyl-CoA C-acyltransferase Saccharomyces cerevisiae S288C 13-17 28263970-7 2017 Moreover, our results indicate that MDH1 generates malate with carbons derived from glutamine, thus enabling utilization of glucose carbons for glycolysis and for biomass. Carbon 63-70 malate dehydrogenase 1 Homo sapiens 36-40 7916689-17 1993 Disruption of POT1 abolished the ability of Y. lipolytica cells to grow on solid media with oleate as a carbon source. Carbon 104-110 acetyl-CoA C-acyltransferase Saccharomyces cerevisiae S288C 14-18 28263970-7 2017 Moreover, our results indicate that MDH1 generates malate with carbons derived from glutamine, thus enabling utilization of glucose carbons for glycolysis and for biomass. Carbon 132-139 malate dehydrogenase 1 Homo sapiens 36-40 7688096-8 1993 DNC also exhibited a high potential for inducing alkali-labile DNA-SSB in rat hepatocytes (70-78% C-T value) and was cytotoxic at concentrations over 0.1 mumole/ml. Carbon 2-3 small RNA binding exonuclease protection factor La Rattus norvegicus 67-70 28467008-3 2017 A finely tuned conformation of the alpha-diazoketone precursor is the key for the success of the late-stage transannular C-H insertion to deliver a bridged six-membered ring and a quaternary stereocenter (C6) between two quaternary carbon atoms (C1 and C7). Carbon 232-238 heterogeneous nuclear ribonucleoprotein C Homo sapiens 246-255 8325842-6 1993 The six c-553 hemes have midpoint potentials at pH 7.0 of +288, -10, -162, -192, -265 and -412 mV versus the normal hydrogen electrode (NHE). Carbon 8-9 solute carrier family 9 member C1 Homo sapiens 136-139 28671628-0 2017 Direct Quantification of Cd2+ in the Presence of Cu2+ by a Combination of Anodic Stripping Voltammetry Using a Bi-Film-Modified Glassy Carbon Electrode and an Artificial Neural Network. Carbon 135-141 CD2 molecule Homo sapiens 25-28 28671628-1 2017 Abstract: In this study, a novel method based on a Bi/glassy carbon electrode (Bi/GCE) for quantitatively and directly detecting Cd2+ in the presence of Cu2+ without further electrode modifications by combining square-wave anodic stripping voltammetry (SWASV) and a back-propagation artificial neural network (BP-ANN) has been proposed. Carbon 61-67 CD2 molecule Homo sapiens 129-132 27324791-3 2017 In this work, we have revealed for the first time the role of central carbon metabolism and metabolic dysfunction in dopaminergic cell death induced by the paraquat (PQ)-alpha-synuclein interaction. Carbon 70-76 synuclein alpha Homo sapiens 170-185 8325842-7 1993 The c-559 heme has a midpoint potential (Em") at pH 7.0 of +11 mV versus NHE. Carbon 4-5 solute carrier family 9 member C1 Homo sapiens 73-76 8100228-2 1993 The yeast AAP1 gene, encoding a putative amino-peptidase, was isolated based on its ability to suppress the temperature-sensitive growth on nonfermentable carbon sources of spr5, a stationary phase regulatory mutant. Carbon 155-161 arginine/alanine aminopeptidase Saccharomyces cerevisiae S288C 10-14 28620663-1 2017 Long single-walled carbon nanotubes, with lengths >10 mum, can be spontaneously dissolved by stirring in a sodium naphthalide N,N-dimethylacetamide solution, yielding solutions of individualised nanotubide ions at concentrations up to 0.74 mg mL-1. Carbon 19-25 L1 cell adhesion molecule Mus musculus 246-250 7683726-2 1993 As described in the preceding paper, yeast require a functional AAC2 (or AAC1) to grow on a non-fermentable carbon source. Carbon 108-114 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 64-68 28607068-5 2017 We use this model to study how tropical peatland carbon storage and fluxes are controlled by changes in climate, sea level, and drainage networks. Carbon 49-55 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 113-116 28466599-3 2017 Pyrolysis of a nanocubic prussian blue analogue precursor (Km Mnx [Co(CN)6 ]y n H2 O) embedded in a bisphenol A and aniline-based pBO led to the formation of a N-doped carbon matrix modified with Mnx Coy Oz nanocubes. Carbon 169-175 keratin 86 Homo sapiens 62-65 8099891-3 1993 Our results point to an involvement in the life cycle of the PHO2 activator and the PHO85-negative factor and to a reduced ability of the negative pho regulatory mutants, pho80 and pho85, to grow on non-fermentable carbon sources. Carbon 215-221 Pho80p Saccharomyces cerevisiae S288C 171-176 28502432-0 2017 Carbon dots for fluorescent detection of alpha-glucosidase activity using enzyme activated inner filter effect and its application to anti-diabetic drug discovery. Carbon 0-6 sucrase-isomaltase Homo sapiens 41-58 28415529-4 2017 A new nanostructure sensor was constructed based on a glassy carbon electrode modified with TMDS-MWCNT (TMDS-MWCNT/GCE). Carbon 61-67 aminomethyltransferase Homo sapiens 104-118 8467796-2 1993 Galactose induces activity by inhibiting the negative regulator GAL80, while glucose, the preferred carbon source, antagonizes GAL4 function by several mechanisms. Carbon 100-106 galactose-responsive transcription factor GAL4 Saccharomyces cerevisiae S288C 127-131 28566698-4 2017 So carbon-exchange of biocrusts (cyanobacteria crusts-AC1/AC2; cyanolichen crust-LC1; chlorolichen crust-LC2; moss crust-MC) utilizing NRW at various temperatures and light-intensities were determined under simulated and insitu mesocosm experiments. Carbon 3-9 long intergenic non-protein coding RNA 1587 Homo sapiens 54-57 8455603-8 1993 As for S. cerevisiae RAS2, GSP2 expression exhibits carbon source dependency, while GSP1 expression does not. Carbon 52-58 Ran GTPase GSP2 Saccharomyces cerevisiae S288C 27-31 28538683-7 2017 We identified an essential role for central carbon (glucose) metabolism in dopaminergic cell death induced by paraquat treatment that is enhanced by the overexpression of alpha-synuclein. Carbon 44-50 synuclein alpha Homo sapiens 171-186 28538683-10 2017 The overexpression of alpha-synuclein further stimulated an increase in glucose uptake and AMPK activity, but impaired glucose metabolism, likely directing additional carbon to the PPP to supply paraquat redox cycling. Carbon 167-173 synuclein alpha Homo sapiens 22-37 8458009-6 1993 The 13C-labeling at C-6 and C-2 in the starting glucoses is well preserved in the C-6 carbon and the C-1 to C-3 carbons, respectively, in the curdlan produced. Carbon 86-92 complement C6 Homo sapiens 20-23 8458009-6 1993 The 13C-labeling at C-6 and C-2 in the starting glucoses is well preserved in the C-6 carbon and the C-1 to C-3 carbons, respectively, in the curdlan produced. Carbon 86-92 complement C6 Homo sapiens 82-85 28471641-3 2017 The achieved FTO CNT electrode has several distinct advantages including a hollow interior in the hybrid nanostructure, fully encapsulated ultrasmall electroactive units, flexible conductive carbon matrix, and stable solid electrolyte interface (SEI) of FTO in cycles. Carbon 191-197 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 13-16 8458009-6 1993 The 13C-labeling at C-6 and C-2 in the starting glucoses is well preserved in the C-6 carbon and the C-1 to C-3 carbons, respectively, in the curdlan produced. Carbon 112-119 complement C6 Homo sapiens 20-23 8311938-2 1993 The basis of the detection system for the assay is the electrochemical oxidation of NADH produced by G6PDH-labelled theophylline at a potential of +150 mV vs Ag/AgCl using platinised activated carbon (PACE) electrodes. Carbon 193-199 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase Homo sapiens 101-106 28484758-7 2017 Isoporphyrin dimers with saturated meso carbons have strong net diatropic ring-current strengths of 20 nA T-1 fulfilling Huckels aromaticity rule. Carbon 40-47 CD5 molecule Homo sapiens 106-109 1335698-6 1992 From these data we conclude that dexamethasone and certain other steroids with an hydroxyl group in the 11th carbon position regulate ACE gene expression of bovine endothelial cells at the transcriptional level via a steroid receptor-mediated mechanism. Carbon 109-115 angiotensin I converting enzyme Bos taurus 134-137 28443913-8 2017 Silicone elastomers show a good agreement between the measured work of adhesion and the predicted results, but carbon black filled hydrogenated nitrile butadiene rubber compounds reveal that strain softening at the crack tip may play an important role in determining the work of adhesion. Carbon 111-117 TOR signaling pathway regulator Homo sapiens 221-224 28461497-8 2017 These studies also revealed that 5-formylTHF, a slow, tight-binding inhibitor of serine hydroxymethyltransferase (SHMT), was enriched in nuclei, accounting for 35% of folate cofactors, explaining previous observations that nuclear SHMT is not a robust source of one-carbons for de novo dTMP biosynthesis. Carbon 266-273 serine hydroxymethyltransferase 1 Homo sapiens 114-118 28284308-0 2017 Enzymatic biosensor based on entrapment of d-amino acid oxidase on gold nanofilm/MWCNTs nanocomposite modified glassy carbon electrode by sol-gel network: Analytical applications for d-alanine in human serum. Carbon 118-124 D-amino acid oxidase Homo sapiens 43-63 28284308-1 2017 Sensing and determination of d-alanine is studied by using an enzymatic biosensor which was constructed on the basis of d-amino acid oxidase (DAAO) immobilization by sol-gel film onto glassy carbon electrode surface modified with nanocomposite of gold nanofilm (Au-NF) and multiwalled carbon nanotubes (MWCNTs). Carbon 191-197 D-amino acid oxidase Homo sapiens 120-140 28284308-1 2017 Sensing and determination of d-alanine is studied by using an enzymatic biosensor which was constructed on the basis of d-amino acid oxidase (DAAO) immobilization by sol-gel film onto glassy carbon electrode surface modified with nanocomposite of gold nanofilm (Au-NF) and multiwalled carbon nanotubes (MWCNTs). Carbon 191-197 D-amino acid oxidase Homo sapiens 142-146 28284308-1 2017 Sensing and determination of d-alanine is studied by using an enzymatic biosensor which was constructed on the basis of d-amino acid oxidase (DAAO) immobilization by sol-gel film onto glassy carbon electrode surface modified with nanocomposite of gold nanofilm (Au-NF) and multiwalled carbon nanotubes (MWCNTs). Carbon 285-291 D-amino acid oxidase Homo sapiens 120-140 31185958-9 2019 Finally, several metabolic pathways known to be reprogrammed in cancer cells are detected as prognostic pathways including glutamate metabolism in SHH subgroup, pentose phosphate pathway and TCA cycle in Group 3, and folate-mediated one carbon-metabolism in Group 4. Carbon 237-243 sonic hedgehog signaling molecule Homo sapiens 147-150 1361510-12 1992 Phosphate buffer-induced protonation of the electron-adduct of thymine at carbon (C(6)) prevents electron transfer to 5-BrU. Carbon 74-80 complement C6 Homo sapiens 82-86 31934031-0 2019 Recombinant C-terminal heparin-binding domain of fibronectin polypeptide protects against liver damage, reduces serum inflammatory cytokines, and decreases mortality in acute liver failure. Carbon 12-13 fibronectin 1 Mus musculus 49-60 31934031-1 2019 This study aimed to evaluate the effect of recombinant C-terminal heparin-binding domain of fibronectin (FNCHBD) polypeptide on live-damage protection, inflammation, and mortality in acute liver failure (ALF) mice. Carbon 55-56 fibronectin 1 Mus musculus 92-103 30886114-6 2019 We found evidence that carbon is reimported as glucose-6-phosphate, forming a cytosolic bypass around the block of stromal triose phosphate isomerase. Carbon 23-29 triosephosphate isomerase Arabidopsis thaliana 123-149 28284308-1 2017 Sensing and determination of d-alanine is studied by using an enzymatic biosensor which was constructed on the basis of d-amino acid oxidase (DAAO) immobilization by sol-gel film onto glassy carbon electrode surface modified with nanocomposite of gold nanofilm (Au-NF) and multiwalled carbon nanotubes (MWCNTs). Carbon 285-291 D-amino acid oxidase Homo sapiens 142-146 27633574-1 2017 The aim of this study was to investigate effects of irradiations with the therapeutic proton and carbon ion beams in two non-small cell lung cancers, CRL5876 adenocarcinoma and HTB177 large cell lung carcinoma. Carbon 97-103 interleukin 31 receptor A Homo sapiens 150-153 27633574-8 2017 Carbon ions caused larger increase in the quantity of p53 and p21 compared to therapeutic protons. Carbon 0-6 H3 histone pseudogene 16 Homo sapiens 62-65 27824279-5 2017 Several carbon sources were assayed for their effects on beta-glucosidase production, significant yields were obtained in media containing lactose 1% (3.0 +- 0.36 U/ml) and wheat bran 2% (4.0 +- 0.4 U/ml). Carbon 8-14 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1a, chloroplastic Triticum aestivum 57-73 27824279-6 2017 The combination of wheat bran at 2% and lactose at 0.8% as carbon source enhanced beta-glucosidase production, which reached 8.5 +- 0.28 U/ml. Carbon 59-65 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1a, chloroplastic Triticum aestivum 82-98 1504511-0 1992 Carbon filtration of EDB-contaminated well water: a one-year study. Carbon 0-6 vesicle associated membrane protein 8 Homo sapiens 21-24 28429737-4 2017 In some breast cancer cells, xCT antiporter expression is upregulated through the antioxidant transcription factor Nrf2 and contributes to their requirement for glucose as a carbon source. Carbon 174-180 solute carrier family 7 member 11 Homo sapiens 29-32 31142000-0 2019 Development of Effective Lipase-Hybrid Nanoflowers Enriched with Carbon and Magnetic Nanomaterials for Biocatalytic Transformations. Carbon 65-71 PAN0_003d1715 Moesziomyces antarcticus 25-31 1660913-2 1991 We show that Poly I:C-induced antiviral activity is completely abrogated by antibodies to interferon-beta (IFN-beta) whereas antibodies to other interferons or to other cytokines have no effect. Carbon 20-21 interferon beta 1 Homo sapiens 90-105 31021042-3 2019 These are then transformed into Co3 O4 -nanoparticle-decorated porous N-doped carbon fibres (ZIF-Co3 O4 /NCF) through multi-step annealing treatment. Carbon 78-84 neutrophil cytosolic factor 4 Homo sapiens 105-108 31021042-8 2019 The excellent electrocatalytic performance of ZIF-Co3 O4 /NCF is probably due to the abundance of active sites of graphitic carbon-wrapped Co3 O4 nanoparticles, as well as the cross-linked fibrous nitrogen-doped carbon texture. Carbon 124-130 neutrophil cytosolic factor 4 Homo sapiens 58-61 31021042-8 2019 The excellent electrocatalytic performance of ZIF-Co3 O4 /NCF is probably due to the abundance of active sites of graphitic carbon-wrapped Co3 O4 nanoparticles, as well as the cross-linked fibrous nitrogen-doped carbon texture. Carbon 212-218 neutrophil cytosolic factor 4 Homo sapiens 58-61 28370936-4 2017 Six redox enzymes are involved, including four alpha-ketoglutarate- and iron(II)-dependent dioxygenases that hydroxylate four sp3 carbons; one flavin-dependent dehydrogenase that is involved in formation of the unsaturated lactone; and the ferric-reductase-like enzyme RbtH, which regioselectively reduces one of the maleic anhydride moieties in rubratoxin B to the gamma-hydroxybutenolide that is critical for PP2A inhibition. Carbon 130-137 protein phosphatase 2 phosphatase activator Homo sapiens 411-415 28411382-3 2017 Serine hydroxymethyl transferase (SHMT1) provides one-carbon units necessary for embryogenesis and defects in one-carbon production result in specific pathological conditions during pregnancy. Carbon 54-60 serine hydroxymethyltransferase 1 Homo sapiens 34-39 1660913-2 1991 We show that Poly I:C-induced antiviral activity is completely abrogated by antibodies to interferon-beta (IFN-beta) whereas antibodies to other interferons or to other cytokines have no effect. Carbon 20-21 interferon beta 1 Homo sapiens 107-115 28411382-3 2017 Serine hydroxymethyl transferase (SHMT1) provides one-carbon units necessary for embryogenesis and defects in one-carbon production result in specific pathological conditions during pregnancy. Carbon 114-120 serine hydroxymethyltransferase 1 Homo sapiens 34-39 1923818-9 1991 In addition, Kl-GAL11 complements a gal11-defect in S. cerevisiae by partially restoring induction of GAL1 expression, growth on nonfermentable carbon sources, and phosphorylation of GAL4. Carbon 144-150 galactokinase Saccharomyces cerevisiae S288C 16-20 28221016-2 2017 Here, a one-step method is used to prepare carbon coated LiNi1/3Co1/3Mn1/3O2 (NCM/C) by applying active carbon as reaction matrix. Carbon 43-49 CWC22 spliceosome associated protein homolog Homo sapiens 78-81 28221016-2 2017 Here, a one-step method is used to prepare carbon coated LiNi1/3Co1/3Mn1/3O2 (NCM/C) by applying active carbon as reaction matrix. Carbon 104-110 CWC22 spliceosome associated protein homolog Homo sapiens 78-81 28221016-7 2017 The superior charge/discharge performance of NCM/C owes much to the carbon coating layer, which is not only helpful to increase the electronic conductivity but also contributive to inhibit the side reactions between LiNi1/3Co1/3Mn1/3O2 and the liquid electrolyte. Carbon 68-74 CWC22 spliceosome associated protein homolog Homo sapiens 45-48 1834695-7 1991 Successive CyDTA and CHAPS treatments eliminated both Ca(2+)-induced tension and ATPase activity, which were recovered by the addition of troponin C. Carbon 11-12 dynein axonemal heavy chain 8 Homo sapiens 81-87 28211874-8 2017 Conversely, the genetic enhancement of these one-carbon metabolism genes in pink1 or parkin mutants was neuroprotective. Carbon 49-55 PTEN-induced putative kinase 1 Drosophila melanogaster 76-81 28211874-9 2017 We conclude that mitochondrial dysfunction caused by mutations in the Pink1/Parkin pathway engages ATF4-dependent activation of one-carbon metabolism as a protective response. Carbon 132-138 PTEN-induced putative kinase 1 Drosophila melanogaster 70-75 28211874-9 2017 We conclude that mitochondrial dysfunction caused by mutations in the Pink1/Parkin pathway engages ATF4-dependent activation of one-carbon metabolism as a protective response. Carbon 132-138 cryptocephal Drosophila melanogaster 99-103 1683521-3 1991 Sequence analysis on the mutant PAH gene of this haplotype 2 patient, who was born to first-cousin parents, disclosed it to be a C-to-T transition in exon 7. Carbon 129-130 phenylalanine hydroxylase Homo sapiens 32-35 28911670-2 2017 A fast and easy method for the fabrication of poly p-ABSA (Pp-ABSA)/ZnO NPs-carbon paste electrode (Pp-ABSA/ZnO NPs-CPE) by cyclic voltammetry was used. Carbon 76-82 carboxypeptidase E Homo sapiens 116-119 1862425-0 1991 A carbon fiber implant to aid interbody lumbar fusion. Carbon 2-8 activation induced cytidine deaminase Homo sapiens 26-29 28289214-3 2017 Here we report that bovine Rh, regenerated instead with a six-carbon-ring retinal chromophore featuring a C11=C12 double bond locked in its cis conformation (Rh6mr), employs an atypical isomerization mechanism by converting 11-cis to an 11,13-dicis configuration for prolonged Gt activation. Carbon 62-68 rhodopsin Bos taurus 27-29 1862425-2 1991 A carbon-fiber-reinforced polymer implant has been designed to aid interbody lumbar fusion. Carbon 2-8 activation induced cytidine deaminase Homo sapiens 63-66 28222594-5 2017 LCCPs with carbon numbers of 21 to 27 were detected in their standard technical mixtures, and MCCPs and LCCPs impurities were detected in the LCCP and MCCP standard technical mixtures, respectively, causing quantification deviations when these mixtures were used for calibration. Carbon 11-17 angiomotin like 2 Homo sapiens 0-4 2025647-4 1991 Measurements of the specific mRNA levels showed a strong stimulation of MET2 gene transcription in yeast transformants grown on galactose as carbon source, corresponding to 50-100-fold the repressed conditions, while only a 2-fold increase of the enzymatic activity was observed. Carbon 141-147 homoserine O-acetyltransferase Saccharomyces cerevisiae S288C 72-76 1822766-8 1991 The presence of a methyl group at the alpha-carbon of L-Tyr and L-dopa also increases the affinity of the ASC system for these agents. Carbon 44-50 steroid sulfatase Mus musculus 106-109 2254275-2 1990 ALA-auxotrophic hemL mutant S. typhimurium cells are deficient in glutamate-1-semialdehyde (GSA) aminotransferase, the enzyme that catalyzes the last step of ALA synthesis via the five-carbon pathway. Carbon 185-191 GSA Hordeum vulgare 92-95 2272921-3 1990 Intraperitoneal administration to murine tumors indicated that the effective dose ranges of the compounds having sp3 carbon at C-13 position were broader than those of the compounds having sp2 carbon. Carbon 117-123 trans-acting transcription factor 3 Mus musculus 113-116 2272921-3 1990 Intraperitoneal administration to murine tumors indicated that the effective dose ranges of the compounds having sp3 carbon at C-13 position were broader than those of the compounds having sp2 carbon. Carbon 127-128 trans-acting transcription factor 3 Mus musculus 113-116 1980817-5 1990 The finding that the carbon analogue 11 (two methylenes for the disulfide bridge) was devoid of activity is consistent with the hypothesis that histamine H2-receptor inhibition is the result of a covalent bond formation by a way of a disulfide-thiol interchange reaction between the disulfide moiety of tetraamine disulfides and a receptor thiol group. Carbon 21-27 histamine receptor H2 Homo sapiens 144-165 2167308-6 1990 Disruption of AAC2 like the pet9 mutation renders yeast unable to grow on a nonfermentable carbon source. Carbon 91-97 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 14-18 2167308-6 1990 Disruption of AAC2 like the pet9 mutation renders yeast unable to grow on a nonfermentable carbon source. Carbon 91-97 ADP/ATP carrier protein PET9 Saccharomyces cerevisiae S288C 28-32 2198534-11 1990 Deletion of both elements resulted in an insufficient amount of RAS2 protein for growth on a non-fermentable carbon source. Carbon 109-115 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 64-68 2387639-7 1990 The deposition of colloidal carbon particles observed in adult rats after hCG-treatment was also not seen in young rats. Carbon 28-34 hypertrichosis 2 (generalised, congenital) Homo sapiens 74-77 2374116-3 1990 Treatment with hCG resulted in a dose-dependent increase in leucocyte concentration in testicular blood vessels and in the number of blood vessels which could be labelled with intravenously injected carbon particles. Carbon 199-205 hypertrichosis 2 (generalised, congenital) Homo sapiens 15-18 2318773-4 1990 Citrate synthase activity (mumol.g-1.min-1) was significantly lower in soleus muscles from HDS rats in both the supported (19.4 +/- 2.3) and freely hanging (20.0 +/- 1.6) hindlimbs compared with C (28.5 +/- 3.1), whereas soleus muscle glycogen concentration (mg/g) was significantly higher in the freely hanging limbs from HDS rats (5.90 +/- 0.31) but not in the supported limbs (3.80 +/- 0.61) compared with C (4.34 +/- 0.50). Carbon 195-196 citrate synthase Rattus norvegicus 0-16 31075851-0 2019 Tensile Behaviors of Lap-Spliced Carbon Fiber-Textile Reinforced Mortar Composites Exposed to High Temperature. Carbon 33-39 LAP Homo sapiens 21-24 33803332-0 2021 Rapid Fabrication of Renewable Carbon Fibres by Plasma Arc Discharge and Their Humidity Sensing Properties. Carbon 31-37 activity regulated cytoskeleton associated protein Homo sapiens 55-58 31075851-9 2019 In addition, a prediction model developed in the previous study was used to predict the tensile behaviors of the lap-spliced carbon fiber-textile reinforced mortar composites exposed to high temperature, and the prediction by the model showed a good agreement with the experimental results. Carbon 125-131 LAP Homo sapiens 113-116 30769152-0 2019 Nonlinear optical characterization of porous carbon materials by CARS, SHG and TPEF. Carbon 45-51 transmembrane protein with EGF like and two follistatin like domains 2 Homo sapiens 79-83 33803332-3 2021 Here, we investigate the use of plasma arc technology to convert renewable electrospun lignin fibres into a new kind of carbon fibre with a globular and porous microstructure. Carbon 120-126 activity regulated cytoskeleton associated protein Homo sapiens 39-42 33803332-4 2021 The influence of arc currents (up to 60 A) on the structural and morphological properties of as-prepared carbon fibres is discussed. Carbon 105-111 activity regulated cytoskeleton associated protein Homo sapiens 17-20 33803332-8 2021 These results demonstrate that the plasma arc technology has great potential for the development of sustainable, lignin-based carbon fibres for a broad range of application in electronics, sensors and energy storage. Carbon 126-132 activity regulated cytoskeleton associated protein Homo sapiens 42-45 30854805-2 2019 In this study, a nitrogen-doped carbon catalyst with high nitrogen content encapsulating cobalt NPs (CoOx @N-C(g)) was synthesized, and characterized in detail by XRD, HRTEM, N2 -physisorption, ICP, CO2 -TPD, and XPS techniques. Carbon 32-38 complement C2 Homo sapiens 199-202 33033153-0 2020 Widespread carbon-bearing materials on near-Earth asteroid (101955) Bennu. Carbon 11-17 GTF2I repeat domain containing 1 Homo sapiens 68-73 30945079-3 2019 With these changes, all the BM-biochar-modified glassy carbon electrodes (BM-biochar/GCEs) exhibited prominent electrochemical properties (e.g., DeltaEp of 119-254 mV compared to 850 mV for bare GCE). Carbon 55-61 aminomethyltransferase Homo sapiens 85-88 30044177-1 2019 The coloration of Citrus fruits is related with the concentration of carotenoids, isoprenoid pigments of 40 carbon atoms (C40). Carbon 108-114 CCR4-NOT transcription complex subunit 11 Homo sapiens 122-125 26019148-3 2015 The FAT1 deletion mutant exhibited decreased growth on n-alkanes of 10-18 carbons, whereas the FAA1 mutant showed growth reduction on n-alkane of 16 carbons. Carbon 74-81 long-chain fatty acid transporter FAT1 Saccharomyces cerevisiae S288C 4-8 30990480-7 2019 Meanwhile, with the assistance of a reduced graphene oxide (rGO) support, the GaPd2 nanoparticles/rGO (20 wt%) electrocatalyst presents outstanding HER activity comparable with that of a carbon-supported Pt catalyst (20% Pt/C). Carbon 187-193 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Homo sapiens 78-83 28772628-1 2017 A number of studies have achieved the consensus that microwave thermal technology can regenerate the granular activated carbon (GAC) more efficiently and energy-conservatively than other technologies. Carbon 120-126 glutaminase Homo sapiens 128-131 7601289-0 1995 Assignment of hyperfine-shifted heme carbon resonances in ferricytochrome b5. Carbon 37-43 HEME Bos taurus 32-36 30160411-1 2017 A microplasma-generating device was developed by using needle-plate electrode discharge with the incorporation a Pt/carbon nanotube (CNT) nanocomposite-decorated FTO electrode. Carbon 116-122 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 162-165 30851693-3 2019 For all the tacrine-tryptophan heterodimers, favorable inhibitory effect on hAChE as well as on hBChE was coined to the optimal spacer length ranging from five to eight carbon atoms between these two pharmacophores. Carbon 169-175 butyrylcholinesterase Homo sapiens 96-101 30916046-1 2019 The synthesis is described of a pH-universal hydrogen evolution electrocatalyst based on N and P co-doped graphitic carbon encapsulated OsP2 (OsP2@NPC) nanoparticles of 1.8 nm size for the electrocatalytic hydrogen evolution reaction (HER). Carbon 116-122 NPC intracellular cholesterol transporter 1 Homo sapiens 142-150 7601289-1 1995 The reverse detection heteronuclear multiple quantum coherence, HMQC, study of native bovine ferricytochrome b5 has provided the complete assignment of hyperfine shifted resonances of heme carbons attached proton(s). Carbon 189-196 HEME Bos taurus 184-188 27880021-0 2017 Engineering the expression level of cytosolic nucleoside diphosphate kinase in transgenic Solanum tuberosum roots alters growth, respiration and carbon metabolism. Carbon 145-151 cytidine/uridine monophosphate kinase 2 Homo sapiens 46-75 27880021-2 2017 In this study we used a targeted metabolomic approach and measurement of physiological parameters to report the effects of the genetic manipulation of cytosolic NDPK (NDPK1) expression on physiology and carbon metabolism in potato (Solanum tuberosum) roots. Carbon 203-209 nucleoside diphosphate kinase Solanum tuberosum 161-165 27880021-2 2017 In this study we used a targeted metabolomic approach and measurement of physiological parameters to report the effects of the genetic manipulation of cytosolic NDPK (NDPK1) expression on physiology and carbon metabolism in potato (Solanum tuberosum) roots. Carbon 203-209 nucleoside diphosphate kinase Solanum tuberosum 167-172 27880021-4 2017 Root growth, O2 uptake, flux of carbon between sucrose and CO2 , levels of reactive oxygen species and some tricarboxylic acid cycle intermediates were positively correlated with levels of NDPK1 expression. Carbon 32-38 nucleoside diphosphate kinase Solanum tuberosum 189-194 30611810-1 2019 In this study, a novel and efficient aptasensor based on immobilization of thiol terminated prostate specific antigen (PSA) binding DNA aptamer onto Au nanoparticles/fullerene C60-chitosan-ionic liquid/multiwalled carbon nanotubes/screen printed carbon electrode has been fabricated for ultrasensitive aptasensing of biomarker PSA. Carbon 214-220 kallikrein related peptidase 3 Homo sapiens 92-117 30611810-1 2019 In this study, a novel and efficient aptasensor based on immobilization of thiol terminated prostate specific antigen (PSA) binding DNA aptamer onto Au nanoparticles/fullerene C60-chitosan-ionic liquid/multiwalled carbon nanotubes/screen printed carbon electrode has been fabricated for ultrasensitive aptasensing of biomarker PSA. Carbon 214-220 kallikrein related peptidase 3 Homo sapiens 119-122 30611810-1 2019 In this study, a novel and efficient aptasensor based on immobilization of thiol terminated prostate specific antigen (PSA) binding DNA aptamer onto Au nanoparticles/fullerene C60-chitosan-ionic liquid/multiwalled carbon nanotubes/screen printed carbon electrode has been fabricated for ultrasensitive aptasensing of biomarker PSA. Carbon 246-252 kallikrein related peptidase 3 Homo sapiens 92-117 7601289-4 1995 Magnetic/electronic asymmetry of heme induced by two axial His makes spread the hyperfine shifted heme carbon resonances over the range of 280 ppm at 25 degrees C, which would be the more sensitive probe than those of proton resonances in characterizing the nature of heme electronic structure of ferricytochrome b5. Carbon 103-109 HEME Bos taurus 33-37 7601289-4 1995 Magnetic/electronic asymmetry of heme induced by two axial His makes spread the hyperfine shifted heme carbon resonances over the range of 280 ppm at 25 degrees C, which would be the more sensitive probe than those of proton resonances in characterizing the nature of heme electronic structure of ferricytochrome b5. Carbon 103-109 HEME Bos taurus 98-102 28185851-9 2017 Greenhouse gas emissions analysis concluded that the most important contribution of the plant to the mitigation of greenhouse gases was the avoidance of on-site fossil fuel use, followed by the diversion of food waste from landfill and that the plant could result in carbon reduction of 2.95kg CO2eq kWh-1 electricity production or 0.741kg CO2eq kg-1 waste treated. Carbon 267-273 complement C2 Homo sapiens 294-297 7601289-4 1995 Magnetic/electronic asymmetry of heme induced by two axial His makes spread the hyperfine shifted heme carbon resonances over the range of 280 ppm at 25 degrees C, which would be the more sensitive probe than those of proton resonances in characterizing the nature of heme electronic structure of ferricytochrome b5. Carbon 103-109 HEME Bos taurus 98-102 30611810-1 2019 In this study, a novel and efficient aptasensor based on immobilization of thiol terminated prostate specific antigen (PSA) binding DNA aptamer onto Au nanoparticles/fullerene C60-chitosan-ionic liquid/multiwalled carbon nanotubes/screen printed carbon electrode has been fabricated for ultrasensitive aptasensing of biomarker PSA. Carbon 246-252 kallikrein related peptidase 3 Homo sapiens 119-122 34801807-3 2022 As transducer, nitrogen doped carbon dots BSA (N-CD/BSA) nanocomposite electrodeposited on pencil graphite electrode was used to covalently immobilize AChE. Carbon 30-36 acetylcholinesterase Apis mellifera 151-155 30848588-2 2019 These compounds were analyzed by 13C NMR spectroscopy, which showed that the acetylide carbon bound to the uranium(VI) center, U- C C-Ar, was shifted strongly downfield, with delta(13C) values ranging from 392.1 to 409.7 ppm for Cl and NMe2 substituted complexes, respectively. Carbon 87-93 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 236-240 28102677-2 2017 The reaction proceeded via attack of the C-3 carbon of the indoles onto the C-2 position of the allylic moiety and intramolecular construction of the trifluoromethyl group by the intramolecular fluorine atom shift from the C-2 position to the C-3 position of the allyl unit. Carbon 45-51 complement C2 Homo sapiens 76-79 28102677-2 2017 The reaction proceeded via attack of the C-3 carbon of the indoles onto the C-2 position of the allylic moiety and intramolecular construction of the trifluoromethyl group by the intramolecular fluorine atom shift from the C-2 position to the C-3 position of the allyl unit. Carbon 45-51 complement C2 Homo sapiens 223-226 30821935-4 2019 Here, an anisotropic microhoneycomb cellulose nanofiber- (CellF)-carbon nanotube (CNT) aerogel (denoted MCCA) is reported that contains unidirectionally aligned penetrating microchannels, which is prepared by a unidirectional freeze-drying method, using the structure-directing function of the CellFs. Carbon 65-71 methylcrotonyl-CoA carboxylase subunit 1 Homo sapiens 104-108 34971968-1 2022 A facile one-step sonochemical activation method is utilized to fabricate biomass-derived 3D porous hard carbon (PHC-1) with tuned-surface and is compared with the conventional two-step activation method. Carbon 105-111 polyhomeotic homolog 1 Homo sapiens 113-118 28117961-0 2017 Flexible Fiber-Shaped Supercapacitor Based on Nickel-Cobalt Double Hydroxide and Pen Ink Electrodes on Metallized Carbon Fiber. Carbon 114-120 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 81-84 34648782-6 2022 Positive correlations were found between raw water dissolved organic carbon (DOC) with an increase in TOX in treated water and between DOC level with TOX content in distributed water, emphasizing a key role of organics in TOX formation. Carbon 69-75 thymocyte selection associated high mobility group box Homo sapiens 102-105 28150006-8 2017 ArCN+, on the other hand, has a dipole moment of greater than 3.5 D, an observable C-N stretching fundamental at 2189.6 cm-1 (4.567 microns), and a viable formation pathway through HCN, a highly-abundant interstellar molecule. Carbon 2-3 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 181-184 30593913-0 2019 The phosphoenolpyruvate carboxylase gene family identification and expression analysis under abiotic and phytohormone stresses in Solanum lycopersicum L. The ubiquitous phosphoenolpyruvate carboxylase enzymes in plants play pivotal role during carbon metabolism in photosynthesis, physicochemical processes, and tolerance to various abiotic or chemical stresses. Carbon 244-250 phosphoenolpyruvate carboxylase Solanum lycopersicum 4-35 30593913-0 2019 The phosphoenolpyruvate carboxylase gene family identification and expression analysis under abiotic and phytohormone stresses in Solanum lycopersicum L. The ubiquitous phosphoenolpyruvate carboxylase enzymes in plants play pivotal role during carbon metabolism in photosynthesis, physicochemical processes, and tolerance to various abiotic or chemical stresses. Carbon 244-250 phosphoenolpyruvate carboxylase Solanum lycopersicum 169-200 28094962-2 2017 This synthetic strategy proceeds via C-O and C-C bond cleavage as well as C-O and C-C bond formations in a single reaction vessel by simple treatment with CsF in the absence of catalyst. Carbon 37-38 colony stimulating factor 2 Homo sapiens 155-158 34648782-6 2022 Positive correlations were found between raw water dissolved organic carbon (DOC) with an increase in TOX in treated water and between DOC level with TOX content in distributed water, emphasizing a key role of organics in TOX formation. Carbon 69-75 thymocyte selection associated high mobility group box Homo sapiens 222-225 28116680-1 2017 The current downturn of the arctic cryosphere, such as the strong loss of sea ice, melting of ice sheets and glaciers, and permafrost thaw, affects the marine and terrestrial carbon cycles in numerous interconnected ways. Carbon 175-181 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 74-77 34846075-0 2022 Missing Member in the MIIMIIISi4N7 Compound Class: Carbothermal Reduction and Nitridation Synthesis Revealing Substitution of N by C and O in CaLu(Si4N7-2xCxOx):Eu2+/Ce3+ (x 0.3). Carbon 131-132 calumenin Homo sapiens 142-146 28151847-0 2017 Desmin detection by facile prepared carbon quantum dots for early screening of colorectal cancer. Carbon 36-42 desmin Homo sapiens 0-6 28151847-3 2017 The obtained ClCQDs were conjugated onto the anti-Desmin, which were applied for testing the Desmin concentration in serum by using linearly fitted relationship with photoluminescence (PL) intensity.The obtained carbon quantum dots are quasispherical graphite nanocrystals with photoluminescence at about 455 nm. Carbon 212-218 desmin Homo sapiens 50-56 28151847-3 2017 The obtained ClCQDs were conjugated onto the anti-Desmin, which were applied for testing the Desmin concentration in serum by using linearly fitted relationship with photoluminescence (PL) intensity.The obtained carbon quantum dots are quasispherical graphite nanocrystals with photoluminescence at about 455 nm. Carbon 212-218 desmin Homo sapiens 93-99 30972319-0 2019 Carbon Nanotubes Modified With Au for Electrochemical Detection of Prostate Specific Antigen: Effect of Au Nanoparticle Size Distribution. Carbon 0-6 kallikrein related peptidase 3 Homo sapiens 67-92 30867454-1 2019 In folate-mediated one-carbon metabolism (FOCM), 5-formyltetrahydrofolate (5fTHF), a one-carbon substituted tetrahydrofolate (THF) vitamer, acts as an intracellular storage form of folate and as an inhibitor of the folate-dependent enzymes phosphoribosylaminoimidazolecarboxamide formyltransferase (AICARFT) and serine hydroxymethyltransferase (SHMT). Carbon 23-29 serine hydroxymethyltransferase 1 Homo sapiens 312-343 30867454-1 2019 In folate-mediated one-carbon metabolism (FOCM), 5-formyltetrahydrofolate (5fTHF), a one-carbon substituted tetrahydrofolate (THF) vitamer, acts as an intracellular storage form of folate and as an inhibitor of the folate-dependent enzymes phosphoribosylaminoimidazolecarboxamide formyltransferase (AICARFT) and serine hydroxymethyltransferase (SHMT). Carbon 23-29 serine hydroxymethyltransferase 1 Homo sapiens 345-349 34794320-4 2022 Methods and Results: In WKY, direct renal interstitial (RI) administration of selective AT2R non-peptide agonist Compound-21 (C-21) increased RI cyclic GMP (cGMP) levels, urine Na+ excretion (UNaV), and simultaneously increased PP2A activity 2-fold in homogenates of renal cortical tubules. Carbon 126-127 angiotensin II receptor, type 2 Rattus norvegicus 88-92 30488772-0 2019 Sugar Transporter Protein 1 (STP1) contributes to regulation of the genes involved in shoot branching via carbon partitioning in Arabidopsis. Carbon 106-112 sugar transporter 1 Arabidopsis thaliana 0-27 30488772-0 2019 Sugar Transporter Protein 1 (STP1) contributes to regulation of the genes involved in shoot branching via carbon partitioning in Arabidopsis. Carbon 106-112 sugar transporter 1 Arabidopsis thaliana 29-33 27923813-2 2017 Nitro-conjugated linoleic acid (NO2-CLA) is preferentially formed, constitutes the most abundant nitrated fatty acid in humans, and contains two carbons that could potentially react with thiols, modulating signaling actions and levels. Carbon 145-152 selectin P ligand Homo sapiens 36-39 27923813-4 2017 Reactions followed reversible biphasic kinetics, consistent with the presence of two electrophilic centers in NO2-CLA located on the beta- and delta-carbons with respect to the nitro group. Carbon 149-156 selectin P ligand Homo sapiens 114-117 34794320-7 2022 CAL treatment abolished C-21-induced translocation of both AT2R and PP2A regulatory subunit B55alpha to apical plasma membranes. Carbon 24-25 angiotensin II receptor, type 2 Rattus norvegicus 59-63 28184233-6 2017 Chemical analysis revealed that overexpression of At5g02890 caused significant reductions in the levels of wax components longer than 28 carbons (C28) in inflorescence stems, whereas the levels of wax molecules of chain length C28 or shorter were significantly increased. Carbon 137-144 HXXXD-type acyl-transferase family protein Arabidopsis thaliana 50-59 34341919-0 2022 Pilot study on the treatment of low carbon and nitrogen ratio municipal sewage by A1/O2/A3/A4/O5 sludge-membrane coupling process with multi-point inflow. Carbon 36-42 immunoglobulin kappa variable 2D-36 (pseudogene) Homo sapiens 88-96 27589399-0 2017 Enzyme precipitate coating of pyranose oxidase on carbon nanotubes and their electrochemical applications. Carbon 50-56 proline dehydrogenase 1 Homo sapiens 30-46 30447588-5 2019 It is observed that, in general, OC3 and EC1 were the dominant thermally evolved carbon mass fractions. Carbon 81-87 Susceptibility to lysis by alloreactive natural killer cells Homo sapiens 41-44 30703319-0 2019 Two-Dimensional Hydroxyl-Functionalized and Carbon-Deficient Scandium Carbide, ScC xOH, a Direct Band Gap Semiconductor. Carbon 44-50 serpin family B member 3 Homo sapiens 79-82 30703319-4 2019 Here, we demonstrate the fabrication of 2D hydroxyl-functionalized and carbon-deficient scandium carbide, namely, ScC xOH, by selective etching of a layered parent ScAl3C3 compound. Carbon 71-77 serpin family B member 3 Homo sapiens 114-117 27589399-1 2017 Pyranose oxidase (POx), which doesn"t have electrically non-conductive glycosylation moiety, was immobilized on carbon nanotubes (CNTs) via three different preparation methods: covalent attachment (CA), enzyme coating (EC) and enzyme precipitate coating (EPC). Carbon 112-118 proline dehydrogenase 1 Homo sapiens 0-16 34341919-1 2022 A new multi-point inflow pre-anoxic/oxic/anaerobic/anoxic/oxic (A1/O2/A3/A4/O5) sludge-membrane coupling process and pilot plant were developed and designed to solve the problem of nitrogen and phosphorus removal of low carbon and nitrogen (C/N) ratio domestic sewage in southern China. Carbon 241-242 immunoglobulin kappa variable 2D-36 (pseudogene) Homo sapiens 70-78 27589399-1 2017 Pyranose oxidase (POx), which doesn"t have electrically non-conductive glycosylation moiety, was immobilized on carbon nanotubes (CNTs) via three different preparation methods: covalent attachment (CA), enzyme coating (EC) and enzyme precipitate coating (EPC). Carbon 112-118 proline dehydrogenase 1 Homo sapiens 18-21 34906906-3 2022 In this context, this study addressed the relationship between the efficacy of talazoparib (TAL) as a PARPi and the activation of TLR3 or TLR9 by Polyinosinic:polycytidylic acid (Poly I:C) or CpG oligodeoxynucleotides (CpG-ODN) stimulation, respectively in triple negative breast cancer (TNBC). Carbon 186-187 toll like receptor 3 Homo sapiens 130-134 27270434-5 2017 Activity of the MAPK pathway, as well as other factors, such as HIF1alpha, Myc and MITF, are among those that control the balance between non-oxidative and oxidative branches of central carbon metabolism. Carbon 186-192 MYC proto-oncogene, bHLH transcription factor Homo sapiens 75-78 27270434-5 2017 Activity of the MAPK pathway, as well as other factors, such as HIF1alpha, Myc and MITF, are among those that control the balance between non-oxidative and oxidative branches of central carbon metabolism. Carbon 186-192 melanocyte inducing transcription factor Homo sapiens 83-87 30508279-4 2019 It is found that Mox C/carbon nanotube (CNT) is highly selective in the cleavage of bonds between carbohydrates and lignin and ether bonds in lignin during the catalytic reductive fractionation of hardwood, leading to a carbohydrate (both cellulose and hemicellulose) retention degree in the solid product close to the theoretical maximum and a delignification degree as high as 98.1 %. Carbon 23-29 monooxygenase DBH like 1 Homo sapiens 17-20 30649875-6 2019 Structure-activity relationship analyses suggested that the binding potencies of PFASs to PPARalpha might depend on LBP binding cavity volume, hydrogen bond interactions, the number of perfluorinated carbons, and the hydrophobicity of PFASs. Carbon 200-207 peroxisome proliferator activated receptor alpha Homo sapiens 90-99 34906906-3 2022 In this context, this study addressed the relationship between the efficacy of talazoparib (TAL) as a PARPi and the activation of TLR3 or TLR9 by Polyinosinic:polycytidylic acid (Poly I:C) or CpG oligodeoxynucleotides (CpG-ODN) stimulation, respectively in triple negative breast cancer (TNBC). Carbon 186-187 toll like receptor 9 Homo sapiens 138-142 34860017-1 2021 In order to overcome the shuttling effect of soluble polysulfides in lithium-sulfur (Li-S) batteries, we have designed and synthesized a creative MoS2-MoO3/carbon shell (MoS2-MoO3/CS) composite by a H2O2-enabled oxidizing process under mild conditions, which is further used for separator modification. Carbon 156-162 citrate synthase Homo sapiens 180-182 30488654-1 2019 N-Heterocyclic carbenes (NHCs, :C) can interact with azolium salts (C-H+ ) by either forming a hydrogen-bonded aggregate (CHC+ ) or a covalent C-C bond (CCH+ ). Carbon 27-28 clathrin heavy chain Homo sapiens 122-126 29214121-4 2017 This work aimed at testing the feasibility of carbon and gold nanoparticles as immunoassay labels for PSA detection with cost-effective optical detection in a novel microfluidic POC platform called microcapillary film (MCF), consisting of a parallel array of fluoropolymer microcapillaries with 200-mum internal diameter. Carbon 46-52 kallikrein related peptidase 3 Homo sapiens 102-105 29214121-5 2017 With neutravidin-coated carbon, nanoparticles were able to quantify an immobilized biotinylated monoclonal antibody (coating solution from 10 to 40 mug/ml) and PSA was successfully quantified in a sandwich assay using silver-enhanced gold nanoparticles and a flatbed scanner; yet, the dynamic range was limited to 10-100 ng/ml. Carbon 24-30 kallikrein related peptidase 3 Homo sapiens 160-163 34952627-0 2021 Carbon catabolite repression involves physical interaction of the transcription factor CRE1/CreA and the Tup1-Cyc8 complex in Penicillium oxalicum and Trichoderma reesei. Carbon 0-6 chromatin-silencing transcriptional regulator TUP1 Saccharomyces cerevisiae S288C 105-109 27894770-6 2017 The sn-1 and sn-2 positions of the glycerol backbone in PC-1 have a quencher terminated 12-carbon chain and fluorophore terminated 11-carbon chain respectively. Carbon 91-97 polycystin 1, transient receptor potential channel interacting Homo sapiens 56-60 27894770-6 2017 The sn-1 and sn-2 positions of the glycerol backbone in PC-1 have a quencher terminated 12-carbon chain and fluorophore terminated 11-carbon chain respectively. Carbon 134-140 polycystin 1, transient receptor potential channel interacting Homo sapiens 56-60 27894770-7 2017 PC-2 has a quencher terminated 3-carbon chain at the sn-2 and chain terminating fluorescent reporter at the sn-1 positions. Carbon 33-39 chromobox 4 Homo sapiens 0-4 30803613-6 2019 An ash content of 4.9 wt% was obtained by using 60 min of soaking time, 60 C of temperature, 10 mL/g of reagent/CBp ratio and HCl 4 M. The demineralized CBp (dCBp) showed a carbon content of 92.9 wt%, while the FRX analysis indicated that SiO2 is the major component into the ash. Carbon 174-180 sarcoplasmic calcium-binding protein Drosophila melanogaster 159-163 34952627-0 2021 Carbon catabolite repression involves physical interaction of the transcription factor CRE1/CreA and the Tup1-Cyc8 complex in Penicillium oxalicum and Trichoderma reesei. Carbon 0-6 transcription regulator CYC8 Saccharomyces cerevisiae S288C 110-114 30712188-10 2019 To compute the above ground biomass carbon stock of trees and shrubs with DBH > 5 cm, their DBH and height were measured. Carbon 36-42 dopamine beta-hydroxylase Homo sapiens 74-77 34879201-3 2021 The eta2 coordination complexes bind side-on, akin to olefins, via a borataalkene unit, although with the carbon atom much more proximal to the metal center than boron. Carbon 106-112 DNA polymerase iota Homo sapiens 4-8 30712188-11 2019 The biomass carbon assessment of woody species having DBH < 5 cm, litter and herb were conducted by measuring their fresh weight in the field and dry weight in the laboratory. Carbon 12-18 dopamine beta-hydroxylase Homo sapiens 54-57 30460315-2 2017 A small amount of commercial pen ink was added to effectively reduce the agglomeration of the GO sheets during solvent evaporation and the following reduction processes in which the presence of graphite carbon nanoparticles served as nano-spacer to separate GO sheets. Carbon 203-209 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 29-32 34546653-2 2021 Here, we firstly introduce an iron-based NASICON-type Na 4 Fe 3 (PO 4 ) 2 (P 2 O 7 ) with carbon layer (NFPP@C) as cathode material for ZIBs. Carbon 90-96 ERC2 intronic transcript 1 Homo sapiens 54-82 27978704-2 2016 The crucial step in this synthesis was an intramolecular Friedel-Crafts reaction at C-4 of the indole derivative driven by the EDG/EWG within a compound that was rationally designed to prevent the cyclization reaction at the C-2 positon of indole, thereby successfully providing the complete carbon framework of 1. Carbon 292-298 complement C4A (Rodgers blood group) Homo sapiens 84-87 27978704-2 2016 The crucial step in this synthesis was an intramolecular Friedel-Crafts reaction at C-4 of the indole derivative driven by the EDG/EWG within a compound that was rationally designed to prevent the cyclization reaction at the C-2 positon of indole, thereby successfully providing the complete carbon framework of 1. Carbon 292-298 complement C2 Homo sapiens 225-228 30520205-2 2019 A cost-effective carbon-supported carbon-defect-anchored platinum single-atom electrocatalysts (Pt1 /C) with remarkable ORR performance is reported. Carbon 17-23 zinc finger protein 77 Homo sapiens 96-99 30520205-2 2019 A cost-effective carbon-supported carbon-defect-anchored platinum single-atom electrocatalysts (Pt1 /C) with remarkable ORR performance is reported. Carbon 34-40 zinc finger protein 77 Homo sapiens 96-99 30605203-1 2019 Ru nanoparticles doped in carbon foam were encapsulated in nitrogen-doped graphite carbon materials (Ru-NGC). Carbon 83-89 chondroitin sulfate proteoglycan 5 Homo sapiens 104-107 34976860-4 2021 In this study, we constructed an A. flavus pgi deletion mutant, which exhibited specific carbon requirement for survival, reduced conidiation, and slowed germination even under optimal experimental conditions. Carbon 89-95 glucose-6-phosphate isomerase Homo sapiens 43-46 31858090-6 2019 Cleavage at the 3" end of the hairpin loop produces RNA end product encoding a C-terminal fragment of betaAPP. Carbon 0-1 amyloid beta (A4) precursor protein Mus musculus 102-109 31930204-5 2019 A member of the ELL family (ELL1) was recently proven to act as an E3 ubiquitin ligase to known proto-oncogene, c-Myc, through a highly conserved cysteine residue in the C-terminal CEYLH region. Carbon 170-171 MYC proto-oncogene, bHLH transcription factor Homo sapiens 96-117 30564911-0 2018 A glassy carbon electrode modified with TiO2(200)-rGO hybrid nanosheets for aptamer based impedimetric determination of the prostate specific antigen. Carbon 9-15 kallikrein related peptidase 3 Homo sapiens 124-149 30317040-1 2018 Because of the eminent adsorptive capacity and rate for dissolved organic molecules compared to conventionally-sized powdered activated carbon (PAC), super-fine powdered activated carbon (SPAC) is gathering momentum for use in not only the pretreatment for membrane filtration for drinking water purification but also the conventional water purification process consisting of coagulation-flocculation, sedimentation, and rapid sand-filtration (CSF). Carbon 180-186 colony stimulating factor 2 Homo sapiens 444-447 30674117-2 2018 The population growth of the species depends on the consumption of two substitutable forms of inorganic carbon, "CO2" (dissolved CO2 and carbonic acid) and "CARB" (bicarbonate and carbonate ions), which are stored internally. Carbon 104-110 complement C2 Homo sapiens 112-116 30205169-3 2018 As in B16 cells, poly I:C plus IFN-gamma synergism reduced UM-SCC1 and UM-SCC38 growth, and no more than 24 h was needed for significant growth reduction. Carbon 24-25 RAD21 cohesin complex component Homo sapiens 62-66 30232842-2 2018 In this study, a metal-organic framework based synthetic route to couple two non-noble-metal-based catalysts, CoP and Mo2 C, supported on nitrogen-doped carbon has been developed. Carbon 153-159 caspase recruitment domain family member 16 Homo sapiens 110-113 30376289-0 2018 Coupling Bimetallic Oxides/Alloys and N-Doped Carbon Nanotubes as Tri-Functional Catalysts for Overall Water Splitting and Zinc-Air Batteries. Carbon 46-52 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 66-69 30303005-1 2018 The major product of the reaction between Ru(IMe4)2(PPh3)2H2 (1; IMe4 = 1,3,4,5-tetramethylimidazol-2-ylidene) and P(C6F5)3 (PCF) is the five-coordinate complex Ru(IMe4)2(PF2{C6F5})(C6F5)H (2), which is formed via a complex series of C-F/P-C bond cleavage and P-F bond formation steps. Carbon 117-118 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Homo sapiens 45-49 30303005-1 2018 The major product of the reaction between Ru(IMe4)2(PPh3)2H2 (1; IMe4 = 1,3,4,5-tetramethylimidazol-2-ylidene) and P(C6F5)3 (PCF) is the five-coordinate complex Ru(IMe4)2(PF2{C6F5})(C6F5)H (2), which is formed via a complex series of C-F/P-C bond cleavage and P-F bond formation steps. Carbon 117-118 protein phosphatase 4 catalytic subunit Homo sapiens 52-56 30143155-0 2018 Preparation of polyethylene glycol diglycidyl ether (PEDGE) crosslinked chitosan/activated carbon composite film for Cd2+ removal. Carbon 91-97 CD2 molecule Homo sapiens 117-120 30143155-8 2018 The obtained PEDGE crosslinked chitosan/activated carbon composite film was used for adsorption of Cd2+. Carbon 50-56 CD2 molecule Homo sapiens 99-102 30143155-10 2018 Based on Langmuir adsorption isotherm model, the maximum adsorption capacity (Q) of Cd2+ by PEDGE crosslinked chitosan/activated carbon composite film was 357.14 mg/g. Carbon 129-135 CD2 molecule Homo sapiens 84-87 29989288-7 2018 Using large-scale optimizations we developed pulse schemes for magnetization transfer from amide nitrogen to carbonyl (NCO) as well as aliphatic carbons (NCA). Carbon 145-152 CEA cell adhesion molecule 6 Homo sapiens 154-157 30355296-10 2018 We searched for additional genes associated with a PhaR-binding sequence and found that some genes involved in central carbon metabolism, such as pdhA for pyruvate dehydrogenase and pckA for phosphoenolpyruvate carboxykinase, may be regulated positively and directly by PhaR. Carbon 119-125 ubiquinone-dependent pyruvate dehydrogenase Bradyrhizobium diazoefficiens USDA 110 155-177 31458090-5 2018 Noncovalent functionalization of carbon nanotubes with the macrocycle-containing conjugated polymer significantly enhanced nanotube solubility, resulting in dark and concentrated nanotube dispersions (600 mug mL-1), as evidenced by UV-vis-NIR spectroscopy and thermogravimetric analysis. Carbon 33-39 L1 cell adhesion molecule Mus musculus 209-213 30360579-3 2018 The two regioselective and successive cross-coupling reactions were first carried out in C-4 by in situ C-O activation and next in C-2 by a methylsulfur release. Carbon 89-90 complement C2 Homo sapiens 131-134 30348171-2 2018 Induction of interferon-induced transmembrane protein 3 (Ifitm3) in astrocytes has a crucial role in polyI:C-induced neurodevelopmental abnormalities. Carbon 107-108 interferon induced transmembrane protein 3 Mus musculus 13-55 30348171-2 2018 Induction of interferon-induced transmembrane protein 3 (Ifitm3) in astrocytes has a crucial role in polyI:C-induced neurodevelopmental abnormalities. Carbon 107-108 interferon induced transmembrane protein 3 Mus musculus 57-63 30348171-3 2018 Through a quantitative proteomic screen, we previously identified candidate astroglial factors, such as matrix metalloproteinase-3 (Mmp3) and follistatin-like 1 (Fstl1), in polyl:C-induced neurodevelopmental impairment. Carbon 179-180 matrix metallopeptidase 3 Mus musculus 104-130 30348171-3 2018 Through a quantitative proteomic screen, we previously identified candidate astroglial factors, such as matrix metalloproteinase-3 (Mmp3) and follistatin-like 1 (Fstl1), in polyl:C-induced neurodevelopmental impairment. Carbon 179-180 matrix metallopeptidase 3 Mus musculus 132-136 30310113-2 2018 Carbon sink assessment scheme based on its forming processes (CSF) is a recently proposed measure but repeatly calculates emission from water erosion and ignored human inducing carbon inputs. Carbon 0-6 colony stimulating factor 2 Homo sapiens 62-65 30310113-2 2018 Carbon sink assessment scheme based on its forming processes (CSF) is a recently proposed measure but repeatly calculates emission from water erosion and ignored human inducing carbon inputs. Carbon 177-183 colony stimulating factor 2 Homo sapiens 62-65 30310113-3 2018 Therefore, we revised the CSF by calculating the direct outputs from land surface and adding human returned carbon (HC) to the input. Carbon 108-114 colony stimulating factor 2 Homo sapiens 26-29 30007624-1 2018 The present work describes the electrochemical detection of Cd2+ using reduced graphene oxide (rGO), carboxymethyl cellulose (CMC) and glutathione (GSH) modified glassy carbon electrode (GCE) by Square Wave Anodic Stripping Voltammetry (SWASV). Carbon 169-175 CD2 molecule Homo sapiens 60-63 29929124-6 2018 The total organic carbon (TOC) analysis revealed that over 90% 4-ClPh was removed when the UV treated TiO2 electrode was employed and the rate constant was 16 times faster than that of the untreated TiO2 electrode; whereas only 60% 4-ClPh was eliminated at the Pt electrode under the same conditions. Carbon 18-24 calcium binding protein, spermatid associated 1 Homo sapiens 65-69 29946959-4 2018 Reductions in 13C fluxes into the specific carbon sites of tricarboxylic acid (TCA) intermediate (succinate) as well as neurotransmitters (glutamate, glutamine, gamma-aminobutyric acid and aspartate) from [1-13C]-glucose were also detected in the brain of APP/PS1 mice. Carbon 43-49 presenilin 1 Mus musculus 260-263 30040045-6 2018 Expression of Mel-CAM and L1-CAM was upregulated after low-dose photon exposure, but decreased with dose, especially after carbon-ion treatment. Carbon 123-129 L1 cell adhesion molecule Mus musculus 26-32 30029416-3 2018 Analytical results clearly showed that the electrochemical and ECL behaviors of proposed biosensing platform on the glassy carbon electrode (GCE) exhibited outstanding performance, which was due to large specific surface area, high carrier mobility and strong pi-pi non-covalent attraction toward single-chain DNA (scDNA) of the stable 3D platform, and ECL amplification of Tri-SNSs. Carbon 123-129 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 374-377 30280025-9 2018 Microbial biomass nitrogen (MBN) and the SOC/STN (soil organic carbon (SOC)) ratio and density treatments influenced MBN concentration and inhibited SOC/STN. Carbon 63-69 UBX domain protein 11 Homo sapiens 41-48 30280025-9 2018 Microbial biomass nitrogen (MBN) and the SOC/STN (soil organic carbon (SOC)) ratio and density treatments influenced MBN concentration and inhibited SOC/STN. Carbon 63-69 UBX domain protein 11 Homo sapiens 41-44 30280025-9 2018 Microbial biomass nitrogen (MBN) and the SOC/STN (soil organic carbon (SOC)) ratio and density treatments influenced MBN concentration and inhibited SOC/STN. Carbon 63-69 eukaryotic translation elongation factor 1 alpha 2 Homo sapiens 45-48 29734086-2 2018 Styrene (ST) and N-vinylimidazole (VIM) were carbon and nitrogen sources, while the sulfonic acid functional groups introduced by the simple concentrated sulfuric acid sulfonation worked simultaneously as cross-linking agent and sulfur source during the following thermal treatments. Carbon 45-51 vimentin Homo sapiens 35-38 29959027-4 2018 Metal-, metal-oxide- and carbon-based nanomaterials may trigger a sterile inflammatory cascade by means of different damage-associated molecular patterns, including chromatin associated protein high-mobility group box-1 secretion, ATP, ADP and adenosine purinergic signaling, interleukin-1alpha alarmin, and NLPR-3 inflammasome activation. Carbon 25-31 interleukin 1 alpha Homo sapiens 276-294 30101584-0 2018 Highly Dispersed Co-B/N Codoped Carbon Nanospheres on Graphene for Synergistic Effects as Bifunctional Oxygen Electrocatalysts. Carbon 32-38 metabolism of cobalamin associated B Homo sapiens 17-21 30101584-3 2018 In this work, we report on the design and synthesis of a novel Co-B/N codoped carbon with core-shell-structured nanoparticles aligned on graphene nanosheets (denoted as CoTIB-C/G) derived from cobalt tetrakis(1-imidazolyl)borate (CoTIB) and graphene oxide hybrid template. Carbon 78-84 metabolism of cobalamin associated B Homo sapiens 63-67 27846987-3 2016 A glassy carbon electrode modified by the nanocomposite was evaluated as a new platform for the simultaneous detection of trace amounts of Cd2+ and Pb2+ using differential pulse anodic stripping voltammetry (DPASV). Carbon 9-15 CD2 molecule Homo sapiens 139-142 27792349-0 2016 Relay Rh(II)/Pd(0) Dual Catalysis: Selective Construction of Cyclic All-Quaternary Carbon Centers. Carbon 83-89 Rh blood group D antigen Homo sapiens 6-12 27792349-1 2016 A novel relay Rh(II)/Pd(0) dual catalysis strategy that promotes the divergent reaction of alpha-diazo-carbonyl compounds with allylic carboxylates for the selective construction of cyclic all-quaternary carbon centers has been developed. Carbon 103-109 Rh blood group D antigen Homo sapiens 14-20 27853174-2 2016 Here we show that a hyperaccumulation effect can allow efficient enrichment of selected metal ions (for example, Sn2+, Mn2+) in the halophytic plants, which can then be converted into three-dimensional carbon/metal oxide (3DC/MOx) nanocomposites with both the composition and structure hierarchy. Carbon 202-208 monooxygenase DBH like 1 Homo sapiens 226-229 27808289-0 2016 Importance of the structural integrity of a carbon conjugated mediator for photocatalytic hydrogen generation from water over a CdS-carbon nanotube-MoS2 composite. Carbon 44-50 CDP-diacylglycerol synthase 1 Homo sapiens 128-131 27808289-1 2016 Incorporation of CdS quantum dots is shown to significantly promote photocatalytic hydrogen production from water over single-layer MoS2 in a remote manner via their dispersions on a carbon nanotube as a nanocomposite: the hydrogen evolution rate is found to be critically dependent on the content and structural integrity of the carbon nanotube such that the double-walled carbon nanotube shows superior H2 production to a single-walled carbon nanotube because the inner carbon tubules survive from the structural damage during functionalization. Carbon 183-189 CDP-diacylglycerol synthase 1 Homo sapiens 17-20 27808289-1 2016 Incorporation of CdS quantum dots is shown to significantly promote photocatalytic hydrogen production from water over single-layer MoS2 in a remote manner via their dispersions on a carbon nanotube as a nanocomposite: the hydrogen evolution rate is found to be critically dependent on the content and structural integrity of the carbon nanotube such that the double-walled carbon nanotube shows superior H2 production to a single-walled carbon nanotube because the inner carbon tubules survive from the structural damage during functionalization. Carbon 330-336 CDP-diacylglycerol synthase 1 Homo sapiens 17-20 27808289-1 2016 Incorporation of CdS quantum dots is shown to significantly promote photocatalytic hydrogen production from water over single-layer MoS2 in a remote manner via their dispersions on a carbon nanotube as a nanocomposite: the hydrogen evolution rate is found to be critically dependent on the content and structural integrity of the carbon nanotube such that the double-walled carbon nanotube shows superior H2 production to a single-walled carbon nanotube because the inner carbon tubules survive from the structural damage during functionalization. Carbon 330-336 CDP-diacylglycerol synthase 1 Homo sapiens 17-20 27808289-1 2016 Incorporation of CdS quantum dots is shown to significantly promote photocatalytic hydrogen production from water over single-layer MoS2 in a remote manner via their dispersions on a carbon nanotube as a nanocomposite: the hydrogen evolution rate is found to be critically dependent on the content and structural integrity of the carbon nanotube such that the double-walled carbon nanotube shows superior H2 production to a single-walled carbon nanotube because the inner carbon tubules survive from the structural damage during functionalization. Carbon 330-336 CDP-diacylglycerol synthase 1 Homo sapiens 17-20 27808289-1 2016 Incorporation of CdS quantum dots is shown to significantly promote photocatalytic hydrogen production from water over single-layer MoS2 in a remote manner via their dispersions on a carbon nanotube as a nanocomposite: the hydrogen evolution rate is found to be critically dependent on the content and structural integrity of the carbon nanotube such that the double-walled carbon nanotube shows superior H2 production to a single-walled carbon nanotube because the inner carbon tubules survive from the structural damage during functionalization. Carbon 330-336 CDP-diacylglycerol synthase 1 Homo sapiens 17-20 27671347-1 2016 In this letter, we report on the use of a cobalt phosphide nanowall array on conductive carbon cloth (CoP NA/CC) as an efficient catalyst electrode for methanol electro-oxidation under alkaline conditions. Carbon 88-94 caspase recruitment domain family member 16 Homo sapiens 102-105 27760045-7 2016 Although Neil3-/- mice displayed normal B cell function, they exhibited elevated serum levels of autoantibodies and developed nephritis following treatment with poly(I:C) to mimic microbial stimulation. Carbon 168-169 nei like 3 (E. coli) Mus musculus 9-14 27523995-2 2016 Monoclonal anti-myoglobin (anti-Mb-IgG) antibody was immobilized on screen-printed multiwalled carbon nanotubes electrode for signal amplification without the need of natural enzymes. Carbon 95-101 myoglobin Homo sapiens 16-25 27523995-2 2016 Monoclonal anti-myoglobin (anti-Mb-IgG) antibody was immobilized on screen-printed multiwalled carbon nanotubes electrode for signal amplification without the need of natural enzymes. Carbon 95-101 myoglobin Homo sapiens 32-34 27459069-7 2016 Screening a panel of peptides with different acyl lysine modifications, we found that HDAC8 can catalyze the removal of acyl groups with 2-16 carbons from lysine 9 of the histone H3 peptide (H3K9). Carbon 142-149 histone deacetylase 8 Homo sapiens 86-91 27686006-7 2016 The evident photoresponse of the FTO/TiO2/MA2MnCl4/carbon electrode devices was observed under 10-30 Hz flashlight frequencies and a 330 nm light beam. Carbon 51-57 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 33-36 27755581-0 2016 The Spatial and Temporal Distribution of Dissolved Organic Carbon Exported from Three Chinese Rivers to the China Sea. Carbon 59-65 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 114-117 32263538-1 2016 Lanthanide hybridized carbon quantum dots (Ln-CQDs) were synthesized by a facile one-pot hydrothermal method using citric acid as a carbon precursor and Yb3+ or Nd3+ as a doping ion. Carbon 22-28 mitochondrially encoded NADH dehydrogenase 3 Homo sapiens 161-164 32263751-1 2016 A novel magnetic-fluorescent manganese(ii)-carbon dots hybrid nanoprobe conjugated with anti-HE4 antibody was successfully prepared for ovarian cancer cell targeting and bifunctional optical and MR imaging. Carbon 43-49 WAP four-disulfide core domain 2 Homo sapiens 93-96 27381428-7 2016 Unlike the complexes 2-4, the reaction of [(COT)Pr(mu-Cl)(THF)2]2 with 1a afforded the unsolvated centrosymmetric complex [(COT)Pr(mu-c-C3H5-C[triple bond, length as m-dash]C-C(N(i)Pr)2)]2 (9). Carbon 44-45 mitogen-activated protein kinase kinase kinase 8 Homo sapiens 124-127 27381428-9 2016 Similar treatment of HoCl3 with 1a or 1b and K2COT as three-component reactions in a 1 : 1 : 1 molar ratio afforded the solvated half-sandwich complexes (COT)Ho(c-C3H5-C[triple bond, length as m-dash]C-C(NR)2)(THF) (13: R = (i)Pr; 14: R = Cy). Carbon 23-24 mitogen-activated protein kinase kinase kinase 8 Homo sapiens 47-50 27381428-10 2016 A unique multidecker sandwich complex [(mu-eta(8):eta(8)-COT){Nd(c-C3H5-C[triple bond, length as m-dash]C-C(NCy)2)(mu-Cl)}2]4 (15) was prepared by reaction of anhydrous NdCl3 with K2COT and 1b in a one-pot reaction. Carbon 16-17 mitogen-activated protein kinase kinase kinase 8 Homo sapiens 57-60 27448312-1 2016 A sensitive and rapid method for the determination of the clinically relevant biomarker human endoglin (CD105) in serum samples is presented, involving a magneto-actuated immunoassay and amperometric detection at disposable screen-printed carbon electrodes (SPCEs). Carbon 239-245 endoglin Homo sapiens 94-102 27660437-0 2016 Construction of magnetic-carbon-quantum-dots-probe-labeled apoferritin nanocages for bioimaging and targeted therapy. Carbon 25-31 ferritin heavy chain 1 Homo sapiens 59-70 27311564-3 2016 We based our work on the previous observation that Esa1p acetylates and activates phosphoenolpyruvate carboxykinase (PEPCK) encoded by PCK1, a rate-limiting enzyme in gluconeogenesis, and subsequently evaluated the activation of Pck1p by yeast growth with non-fermentable carbon sources, thus dependent on gluconeogenesis. Carbon 272-278 phosphoenolpyruvate carboxykinase PCK1 Saccharomyces cerevisiae S288C 135-139 27289207-8 2016 This difference was attributed to the higher concentration of alkyl-Carbon that creates strong links with CLP-m in the hydrophobic micelle-core of the surfactants. Carbon 68-74 calmodulin like 3 Homo sapiens 106-109 27174718-8 2016 Overall, this study demonstrates for the first time that carbon atoms can be lost in the PPP, by means other than the oxidative PPP, and that this loss of carbon atoms is consistent with the hypothesized TKTL1 reaction in mammalian cells. Carbon 57-63 transketolase like 1 Homo sapiens 204-209 27174718-8 2016 Overall, this study demonstrates for the first time that carbon atoms can be lost in the PPP, by means other than the oxidative PPP, and that this loss of carbon atoms is consistent with the hypothesized TKTL1 reaction in mammalian cells. Carbon 155-161 transketolase like 1 Homo sapiens 204-209 27585591-5 2016 Thus, due to lack of inhibition of PFKFB3, IKKbeta-deficient cells exhibit elevated aerobic glycolysis and lactate production, leading to less glucose carbons contributing to tricarboxylic acid (TCA) cycle intermediates and the pentose phosphate pathway, which results in increased glutamine dependence for both TCA cycle intermediates and reactive oxygen species suppression. Carbon 151-158 inhibitor of nuclear factor kappa B kinase subunit beta Homo sapiens 43-50 27045203-1 2016 We use large-scale MP2 calculations to investigate the physisorption of molecular hydrogen on (9,0) defective carbon nanotubes (CNTs) of C72H18. Carbon 110-116 tryptase pseudogene 1 Homo sapiens 19-22 27185934-4 2016 Our results indicate that eCO2 not only slows down the decline of ecosystem carbon uptake during the ECE but also enhances its recovery after the ECE, as mediated by increases of root growth and plant nitrogen uptake induced by the ECE. Carbon 76-82 endothelin converting enzyme 1 Homo sapiens 101-104 27258319-9 2016 (ii) During the post-hypoxia recovery period, the alanine aminotransferase/glutamate dehydrogenase cycle mobilizes this carbon from alanine store. Carbon 120-126 glutamate dehydrogenase 1 Homo sapiens 75-98 26808243-4 2016 Compared to the pure CoFe2O4, the as-prepared CoFe2O4/TNTs not only exhibited better performance in catalytic decomposition of Rhodamine B, but also realized higher total organic carbon removal and less cobalt leaching, which could be attributed to the enhanced catalytic ability from smaller CoFe2O4 nanoparticles and the unique ion-exchange ability from TNTs support. Carbon 179-185 troponin T1, slow skeletal type Homo sapiens 46-58 27153534-4 2016 Phosphorylation of these enzymes leads to enhanced HK activity to sustain glucose uptake but reduced activity of FBP1 to block the gluconeogenic route and reduced activity of PFK1 and ENO1 to moderate drop of glucose-6-phosphate and to repartition more carbon flux to pentose phosphate pathway (PPP), maintaining cellular energy and redox homeostasis at cellular and organismal levels. Carbon 253-259 phosphofructokinase, muscle Homo sapiens 175-179 27153534-4 2016 Phosphorylation of these enzymes leads to enhanced HK activity to sustain glucose uptake but reduced activity of FBP1 to block the gluconeogenic route and reduced activity of PFK1 and ENO1 to moderate drop of glucose-6-phosphate and to repartition more carbon flux to pentose phosphate pathway (PPP), maintaining cellular energy and redox homeostasis at cellular and organismal levels. Carbon 253-259 enolase 1 Homo sapiens 184-188 25880894-5 2016 For instance, soft- and reactive landing have been applied to study the surface chemistry of ions isolated in the gas-phase, prepare arrays of proteins for high-throughput biological screening, produce novel carbon-based and polymer materials, enrich the secondary structure of peptides and the chirality of organic molecules, immobilize electrochemically-active proteins and organometallics on electrodes, create thin films of complex molecules, and immobilize catalytically active organometallics as well as ligated metal clusters. Carbon 208-214 POC1 centriolar protein A Homo sapiens 14-18 26677860-0 2016 Allochthonous Carbon--a Major Driver of Bacterioplankton Production in the Subarctic Northern Baltic Sea. Carbon 14-21 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 101-104 26996571-5 2016 The frequency of allergic rhinitis treatment during the past 12 months increased significantly with exposure to Black Carbon (1.60, 95% CIs 1.36-1.90) (p<0.001), SO2 (1.09, 95% CIs 1.01-1.17) (p<0.05), NO2 (1.18, 95% CIs 1.07-1.30) (p<0.01) for all subjects. Carbon 118-124 cytokine inducible SH2 containing protein Homo sapiens 136-141 26996571-5 2016 The frequency of allergic rhinitis treatment during the past 12 months increased significantly with exposure to Black Carbon (1.60, 95% CIs 1.36-1.90) (p<0.001), SO2 (1.09, 95% CIs 1.01-1.17) (p<0.05), NO2 (1.18, 95% CIs 1.07-1.30) (p<0.01) for all subjects. Carbon 118-124 cytokine inducible SH2 containing protein Homo sapiens 180-185 26996571-5 2016 The frequency of allergic rhinitis treatment during the past 12 months increased significantly with exposure to Black Carbon (1.60, 95% CIs 1.36-1.90) (p<0.001), SO2 (1.09, 95% CIs 1.01-1.17) (p<0.05), NO2 (1.18, 95% CIs 1.07-1.30) (p<0.01) for all subjects. Carbon 118-124 cytokine inducible SH2 containing protein Homo sapiens 180-185 27103750-3 2016 The effect of the surface termination was the same for both the nanostructured B-UNCD film with sp2-bonded carbon atoms in the grain boundaries and the well faceted B-MCD film with micron-sized grains and largely devoid of sp2 carbon. Carbon 107-113 Sp2 transcription factor Equus caballus 96-99 26873212-1 2016 A facile and effective approach of fabricating oxidized multiwalled carbon nanotube/glassy carbon electrode (OMWCNT/GCE) is herein reported. Carbon 91-97 aminomethyltransferase Homo sapiens 109-119 26476598-3 2016 This study focuses on the development of an immunosensor utilizing carbon nanotube (CNT) electrodes coated with gold nanoparticles for the detection of cTx, which could ultimately lead to the development of an inexpensive and rapid point-of-care (POC) tool for bone metabolism detection and prognostics. Carbon 67-73 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 152-155 26518975-3 2016 The biological assay indicated that replacing N(10) with carbon would significantly increase inhibitory activities against DHFR and cytotoxicities against cancer cell lines. Carbon 57-63 dihydrofolate reductase Homo sapiens 123-127 26717037-1 2016 Serine hydroxymethyltransferase (SHMT) is a central enzyme in the metabolic reprogramming of cancer cells, providing activated one-carbon units in the serine-glycine one-carbon metabolism. Carbon 131-137 serine hydroxymethyltransferase 1 Homo sapiens 33-37 26717037-1 2016 Serine hydroxymethyltransferase (SHMT) is a central enzyme in the metabolic reprogramming of cancer cells, providing activated one-carbon units in the serine-glycine one-carbon metabolism. Carbon 170-176 serine hydroxymethyltransferase 1 Homo sapiens 33-37 26724762-3 2016 The assay was carried out on the monoclonal mouse anti-myoglobin (capture) antibody-anchored glassy carbon electrode using polyclonal rabbit anti-myoglobin (detection) antibody-labeled AuNP-PAMAM as the signal tag. Carbon 100-106 myoglobin Homo sapiens 55-64 34391149-9 2021 The results indicate that: (1) cropland use systems acted as net carbon sinks in China with sequestration and emissions of 5.624 t/hm2 and 1.980 t/hm2, respectively. Carbon 65-71 cholinergic receptor muscarinic 2 Homo sapiens 131-134 26638999-3 2016 CYP27A1 could be localized at the cell"s polyhydroxybutyrate (PHB) granules, carbon storage serving organelle-like vesicles that can take up cholesterol, resulting in bioreactor-like structures in B. megaterium . Carbon 77-83 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 0-7 34391149-9 2021 The results indicate that: (1) cropland use systems acted as net carbon sinks in China with sequestration and emissions of 5.624 t/hm2 and 1.980 t/hm2, respectively. Carbon 65-71 cholinergic receptor muscarinic 2 Homo sapiens 147-150 26777976-2 2016 A novel highly sensitive photoelectrochemical (PEC) aptsensor was developed for the detection of TXNDC5 by using the nanohybrids (TiO2 NRs/NCQDs) of nitrogen-doped carbon quantum dots (NCQDs) and TiO2 nanorods as the photo-to-electron conversion medium. Carbon 164-170 thioredoxin domain containing 5 Homo sapiens 97-103 34617655-2 2021 Compared with the labile parent cyclopentadienone, the HOMO-energy of the related eta 2 -complex was significantly raised via the back-bonding of Pd(0) as a pi-Lewis base, rendering the uncoordinated C=C bond as an electron-richer dienophile in inverse-electron-demand aza-Diels-Alder-type reaction with diverse 1-azadienes. Carbon 200-201 DNA polymerase iota Homo sapiens 82-87 26780827-2 2016 Polyinosinic-polycytidylic acid [poly(I:C)] is a synthetic analog of dsRNA that activates different molecules, such as retinoic acid-inducible gene I, melanoma differentiation-associated gene 5, and toll-like receptor-3 (TLR3). Carbon 40-42 toll-like receptor 3 Rattus norvegicus 221-225 34617655-2 2021 Compared with the labile parent cyclopentadienone, the HOMO-energy of the related eta 2 -complex was significantly raised via the back-bonding of Pd(0) as a pi-Lewis base, rendering the uncoordinated C=C bond as an electron-richer dienophile in inverse-electron-demand aza-Diels-Alder-type reaction with diverse 1-azadienes. Carbon 202-203 DNA polymerase iota Homo sapiens 82-87 34984255-1 2021 Silver nanoparticles decorated on an exfoliated graphitic carbon nitride/carbon sphere (AgNP/Eg-C3N4/CS) nanocomposites were synthesized by an adsorption method with a self-assembled process. Carbon 73-79 citrate synthase Homo sapiens 101-103 26703257-1 2016 A simple, selective and sensitive sensor based on mesoporous silica nanoparticles modified carbon paste electrode (MSNs/CPE) is introduced for electrochemical determination of tyrosine (Tyr) and tryptophan (Trp). Carbon 91-97 carboxypeptidase E Homo sapiens 120-123 34903756-4 2021 In these systems, thymidine (T)-to-cytosine (C) substitutions in the scaffold region of the sgRNA or the TATA box-containing loxP sequence (TATAloxP) are corrected by the nCas9-CDA, leading to activation of the next sgRNA. Carbon 45-46 cytidine deaminase Homo sapiens 177-180 27221886-3 2016 Here we found that telomerase activity was suppressed by carbon-ion irradiation via hTERT down-regulation. Carbon 57-63 telomerase reverse transcriptase Homo sapiens 84-89 27221886-5 2016 hTERT suppression caused by either carbon-ion irradiation or MST-312 impaired mitochondrial function, as indicated by decreased membrane potential, mtDNA copy number, mitochondrial mass, total ATP levels and elevated reactive oxygen species (ROS). Carbon 35-41 telomerase reverse transcriptase Homo sapiens 0-5 34426315-0 2021 Regulation of electronic structures of MOF-derived carbon via ligand adjustment for enhanced Fenton-like reactions. Carbon 51-57 lysine acetyltransferase 8 Homo sapiens 39-42 26439318-4 2016 To increase the yield of malic acid by the muC strain significantly, the carbon flux from pyruvate was redirected to oxaloacetate by expressing an exogenous pyruvate carboxylase (PCx) gene from Corynebacterium glutamicum ATCC 13032 in the chromosome of T. fusca muC-16. Carbon 73-79 pyruvate carboxylase Corynebacterium glutamicum ATCC 13032 157-177 26439318-4 2016 To increase the yield of malic acid by the muC strain significantly, the carbon flux from pyruvate was redirected to oxaloacetate by expressing an exogenous pyruvate carboxylase (PCx) gene from Corynebacterium glutamicum ATCC 13032 in the chromosome of T. fusca muC-16. Carbon 73-79 pyruvate carboxylase Corynebacterium glutamicum ATCC 13032 179-182 26774662-0 2016 G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation. Carbon 85-91 ATM serine/threonine kinase Homo sapiens 75-78 34859948-7 2022 We fit lattice gas models of hard carbon sodiation to experimental EP and system enthalpy, obtaining: 1. a theoretical maximum capacity, 2. interlayer versus pore filled sodium with state of charge. Carbon 34-40 epiregulin Homo sapiens 67-69 26827839-8 2016 Knockdown of STING impaired the IFN-beta response triggered by poly(dA:dT), poly(I:C) or SeV. Carbon 83-84 interferon beta-1 Bos taurus 32-40 34854445-1 2021 Monomeric organolithium (LiR) complexes could provide enhanced Li-C bond reactivity and suggest mechanisms for a plethora of LiR-mediated reactions. Carbon 66-67 CD300c molecule Homo sapiens 25-28 26492361-4 2015 Double C-H activation of 1a and 1b was significantly more facile on reaction with [OsCl2(PPh3)3], providing the per-NHC complexes [OsHCl(PPh3){kappa(3)-P,C,P"-C(NCH2PR2)2C10H6}] (R = Cy 7a, R = Ph 7b, respectively), each as two isomers. Carbon 7-8 protein phosphatase 4 catalytic subunit Homo sapiens 89-93 26492361-4 2015 Double C-H activation of 1a and 1b was significantly more facile on reaction with [OsCl2(PPh3)3], providing the per-NHC complexes [OsHCl(PPh3){kappa(3)-P,C,P"-C(NCH2PR2)2C10H6}] (R = Cy 7a, R = Ph 7b, respectively), each as two isomers. Carbon 7-8 protein phosphatase 4 catalytic subunit Homo sapiens 137-141 26492361-4 2015 Double C-H activation of 1a and 1b was significantly more facile on reaction with [OsCl2(PPh3)3], providing the per-NHC complexes [OsHCl(PPh3){kappa(3)-P,C,P"-C(NCH2PR2)2C10H6}] (R = Cy 7a, R = Ph 7b, respectively), each as two isomers. Carbon 85-86 protein phosphatase 4 catalytic subunit Homo sapiens 89-93 26492361-4 2015 Double C-H activation of 1a and 1b was significantly more facile on reaction with [OsCl2(PPh3)3], providing the per-NHC complexes [OsHCl(PPh3){kappa(3)-P,C,P"-C(NCH2PR2)2C10H6}] (R = Cy 7a, R = Ph 7b, respectively), each as two isomers. Carbon 85-86 protein phosphatase 4 catalytic subunit Homo sapiens 137-141 26120817-1 2015 A high sensitive label-free electrochemiluminescence (ECL) immunosensor was fabricated for the detection of prostate specific antigen (PSA) based on potassium niobate-Au nanoparticles@bismuth sulfide (KNbO3-Au NPs@Bi2S3) modified glassy carbon electrode (GCE). Carbon 237-243 kallikrein related peptidase 3 Homo sapiens 108-133 26120817-1 2015 A high sensitive label-free electrochemiluminescence (ECL) immunosensor was fabricated for the detection of prostate specific antigen (PSA) based on potassium niobate-Au nanoparticles@bismuth sulfide (KNbO3-Au NPs@Bi2S3) modified glassy carbon electrode (GCE). Carbon 237-243 kallikrein related peptidase 3 Homo sapiens 135-138 34534889-3 2021 In this study, the ligand binding domain called venus flytrap (VFT) domain of the umami taste receptor protein T1R1 was used as a recognition element, and an electrochemical biosensor based on a double-signal amplification strategy was constructed using single-walled carbon nanotubes (SWCNTs) and Prussian blue (PB). Carbon 268-274 taste 1 receptor member 1 Homo sapiens 111-115 26221781-10 2015 In conclusions, our studies reveal that metabolism via GDH serves an important anaplerotic role by adding net carbon to the TCA cycle. Carbon 110-116 glutamate dehydrogenase 1 Homo sapiens 55-58 34310895-4 2021 However, DPP-4 inhibition resulted in decreased plasma insulin, cardiac DPP-4 activity, FFA, TG and TG/HDL-C ratio and alkaline phosphatase. Carbon 107-108 dipeptidylpeptidase 4 Rattus norvegicus 9-14 26283098-5 2015 A slurry of the carbon produced from sucrose graphitization was made with polyvinylpyrrolidone (PVP) as a surfactant and a coating was obtained by doctor blading the slurry over the FTO glass substrate. Carbon 16-22 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 182-185 26759827-1 2016 Among 272 patients undergoing a screening colonoscopy, DNA methylation of DNMT3B and MTHFR, genes encoding enzymes critical to one-carbon metabolism, was quantified in blood leukocytes using Sequenom EpiTYPER . Carbon 131-137 DNA methyltransferase 3 beta Homo sapiens 74-80 29991441-1 2018 Serine hydroxymethyltransferase (SHMT) is a pivotal enzyme in one-carbon metabolism that catalyses the reversible conversion of serine and tetrahydrofolate into glycine and methylenetetrahydrofolate. Carbon 66-72 serine hydroxymethyltransferase 1 Homo sapiens 0-31 29991441-1 2018 Serine hydroxymethyltransferase (SHMT) is a pivotal enzyme in one-carbon metabolism that catalyses the reversible conversion of serine and tetrahydrofolate into glycine and methylenetetrahydrofolate. Carbon 66-72 serine hydroxymethyltransferase 1 Homo sapiens 33-37 29991441-3 2018 Research on one-carbon metabolism in cancer cell lines has shown that SHMT1 preferentially catalyses serine synthesis, whereas in mitochondria SHMT2 is involved in serine breakdown. Carbon 16-22 serine hydroxymethyltransferase 1 Homo sapiens 70-75 29991441-10 2018 Moreover, our data provide the proof-of-concept that SHMT inhibitors selectively targeting the directionality of one-carbon metabolism flux could be designed. Carbon 117-123 serine hydroxymethyltransferase 1 Homo sapiens 53-57 33682565-7 2021 Furthermore, the detailed interaction mechanism towards CYP2J2 was explicated by docking and molecular dynamics, and our results revealed the residue Thr114 and Thr 315 of CYP2J2 were the critical sites of action, moreover the spatial distance between the carbon atom of ligand methylene and Fe atom of iron porphyrin coenzyme was the vital interaction factor towards human CYP2J2. Carbon 256-262 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 56-62 29959734-0 2018 Equilibrium adsorption study of the adsorptive removal of Cd2+ and Cr6+ using activated carbon. Carbon 88-94 CD2 molecule Homo sapiens 58-61 29959734-3 2018 The adsorption isotherms of Cd2+ and Cr6+ on activated carbon can fit the Langmuir model well, and correlation coefficients were above 0.99, all higher than the Freundlich and Temkin models. Carbon 55-61 CD2 molecule Homo sapiens 28-31 29959734-8 2018 The speciation on activated carbon was mainly residual Cd2+ and Cr6+, and the potential ecological risk of Cd2+ is higher than that of Cr6+. Carbon 28-34 CD2 molecule Homo sapiens 55-58 29959734-8 2018 The speciation on activated carbon was mainly residual Cd2+ and Cr6+, and the potential ecological risk of Cd2+ is higher than that of Cr6+. Carbon 28-34 CD2 molecule Homo sapiens 107-110 29959734-9 2018 The adsorptions of Cd2+ and Cr6+ on activated carbon were dominated by chelation and ion exchange, respectively. Carbon 46-52 CD2 molecule Homo sapiens 19-22 28793659-0 2015 Experimental Characterization of the Properties of Double-Lap Needled and Hybrid Joints of Carbon/Epoxy Composites. Carbon 91-97 LAP Homo sapiens 58-61 26460051-0 2015 Carbon choices determine US cities committed to futures below sea level. Carbon 0-6 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 62-65 26460051-1 2015 Anthropogenic carbon emissions lock in long-term sea-level rise that greatly exceeds projections for this century, posing profound challenges for coastal development and cultural legacies. Carbon 14-20 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 49-52 26460051-2 2015 Analysis based on previously published relationships linking emissions to warming and warming to rise indicates that unabated carbon emissions up to the year 2100 would commit an eventual global sea-level rise of 4.3-9.9 m. Based on detailed topographic and population data, local high tide lines, and regional long-term sea-level commitment for different carbon emissions and ice sheet stability scenarios, we compute the current population living on endangered land at municipal, state, and national levels within the United States. Carbon 126-132 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 195-198 33682565-7 2021 Furthermore, the detailed interaction mechanism towards CYP2J2 was explicated by docking and molecular dynamics, and our results revealed the residue Thr114 and Thr 315 of CYP2J2 were the critical sites of action, moreover the spatial distance between the carbon atom of ligand methylene and Fe atom of iron porphyrin coenzyme was the vital interaction factor towards human CYP2J2. Carbon 256-262 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 172-178 26460051-2 2015 Analysis based on previously published relationships linking emissions to warming and warming to rise indicates that unabated carbon emissions up to the year 2100 would commit an eventual global sea-level rise of 4.3-9.9 m. Based on detailed topographic and population data, local high tide lines, and regional long-term sea-level commitment for different carbon emissions and ice sheet stability scenarios, we compute the current population living on endangered land at municipal, state, and national levels within the United States. Carbon 126-132 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 321-324 29677801-5 2018 In particular, the thermodynamic equilibrium composition of bio-ethanol reforming with the reaction temperature and steam/carbon ratio to produce synthetic gas was examined using the HSC (Enthalpy-Entropy-Heat capacity) chemistry program in this study. Carbon 122-128 fucosyltransferase 1 (H blood group) Homo sapiens 183-186 33682565-7 2021 Furthermore, the detailed interaction mechanism towards CYP2J2 was explicated by docking and molecular dynamics, and our results revealed the residue Thr114 and Thr 315 of CYP2J2 were the critical sites of action, moreover the spatial distance between the carbon atom of ligand methylene and Fe atom of iron porphyrin coenzyme was the vital interaction factor towards human CYP2J2. Carbon 256-262 cytochrome P450 family 2 subfamily J member 2 Homo sapiens 374-380 26526304-0 2015 Diallyl disulfide attenuated carbon ion irradiation-induced apoptosis in mouse testis through changing the ratio of Tap73/DeltaNp73 via mitochondrial pathway. Carbon 29-35 transformation related protein 73 Mus musculus 116-121 26526304-0 2015 Diallyl disulfide attenuated carbon ion irradiation-induced apoptosis in mouse testis through changing the ratio of Tap73/DeltaNp73 via mitochondrial pathway. Carbon 29-35 transformation related protein 73 Mus musculus 122-131 34192988-0 2021 Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect. Carbon 55-62 phosphoglycerate dehydrogenase Homo sapiens 11-16 26526304-3 2015 In this study, the magnitude of radiation effects evoked by carbon ion irradiation was marked by morphology changes, significant rise in apoptotic cells, activation expression of p53, up regulation the ratio of pro-apoptotic Tap73/anti-apoptotic DeltaNp73, as well as alterations of crucial mediator of the mitochondrial pathway. Carbon 60-66 transformation related protein 53, pseudogene Mus musculus 179-182 26526304-3 2015 In this study, the magnitude of radiation effects evoked by carbon ion irradiation was marked by morphology changes, significant rise in apoptotic cells, activation expression of p53, up regulation the ratio of pro-apoptotic Tap73/anti-apoptotic DeltaNp73, as well as alterations of crucial mediator of the mitochondrial pathway. Carbon 60-66 transformation related protein 73 Mus musculus 225-230 26526304-3 2015 In this study, the magnitude of radiation effects evoked by carbon ion irradiation was marked by morphology changes, significant rise in apoptotic cells, activation expression of p53, up regulation the ratio of pro-apoptotic Tap73/anti-apoptotic DeltaNp73, as well as alterations of crucial mediator of the mitochondrial pathway. Carbon 60-66 transformation related protein 73 Mus musculus 246-255 30088438-2 2018 Aim of this study was to evaluate impact of genetic variants in the key genes involved in ara-C metabolism on the leukemic cell intracellular levels of ara-CTP. Carbon 94-95 solute carrier family 25 member 1 Homo sapiens 156-159 34192988-1 2021 The small-molecule inhibitor of phosphoglycerate dehydrogenase, NCT-503, reduces incorporation of glucose-derived carbons into serine in vitro. Carbon 114-121 phosphoglycerate dehydrogenase Homo sapiens 32-62 34883659-4 2021 TEM, XPS, Raman spectroscopy, and TGA characterizations revealed that C/S ratio has a significant impact on the physical and chemical properties of the nanotubes. Carbon 70-71 T-box transcription factor 1 Homo sapiens 34-37 26164304-2 2015 Heat generated by the tip-enhanced electric field is directly transferred to single-walled carbon nanotubes by heat conduction and radiation at the nanoscale. Carbon 91-97 TOR signaling pathway regulator Homo sapiens 22-25 29853044-1 2018 An adsorptive stripping voltammetric method for the determination of As(III) and Astotal in water samples using a carrageenan modified carbon paste electrode is presented for the first time (CAR-CPE). Carbon 135-141 carboxypeptidase E Homo sapiens 195-198 34885360-1 2021 A new type of nano-adsorbent zinc-silver nanoparticles ornamented by multi-walled carbon nanotubes (Zn-Ag MWCNT) was efficiently synthesized by double arc discharge using a newly designed rotating cylinder electrode. Carbon 82-88 activity regulated cytoskeleton associated protein Homo sapiens 151-154 31549035-0 2018 Rechargeable Na-CO2 Batteries Starting from Cathode of Na2CO3 and Carbon Nanotubes. Carbon 66-72 complement C2 Homo sapiens 16-19 26383015-2 2015 The polymers on glassy carbon electrodes were obtained by electropolymerization processes of the monomeric MTRP. Carbon 23-29 lysosomal protein transmembrane 4 alpha Homo sapiens 107-111 31549035-4 2018 Here we report the Na-CO2 batteries, starting from the cathode of cheap Na2CO3 and multiwalled carbon nanotubes (CNTs). Carbon 95-101 complement C2 Homo sapiens 22-25 34714315-0 2021 Electronic properties of 2D and 1D carbon allotropes based on a triphenylene structural unit. Carbon 35-41 leiomodin 1 Homo sapiens 25-34 31549035-8 2018 This work reveals that safe rechargeable Na-CO2 batteries could be constructed by cheap Na2CO3 and multiwalled carbon nanotubes. Carbon 111-117 complement C2 Homo sapiens 44-47 30068074-2 2018 In addition, TTF + was electrochemically reduced back to TTF on a carbon electrode, to be further protonated to continuously produce H2 photochemically. Carbon 66-72 ras homolog family member H Homo sapiens 13-16 30068074-2 2018 In addition, TTF + was electrochemically reduced back to TTF on a carbon electrode, to be further protonated to continuously produce H2 photochemically. Carbon 66-72 ras homolog family member H Homo sapiens 57-60 26188334-9 2015 Stimulation of the opening of the non-selective pore in mitochondria correlated with CNP release from mitochondria in parallel with release of cytochrome c, AIF and Endo G. Carbon 42-43 2',3'-cyclic nucleotide 3' phosphodiesterase Rattus norvegicus 85-88 26332158-3 2015 Existing assignments were sucessfully transferred to a large part of the YadA-M protein in the E. coli lipid environment by using (13) C-(13) C DARR and PDSD spectra at different mixing times. Carbon 135-136 hypothetical protein YadA Escherichia coli 73-79 34198142-2 2021 The well-designed porous carbon coating offers an attractive advantage compared to the common carbon coatings, namely, it can not only better mitigate the volumetric variation of SnO2 by means of its spongy structure with better flexibility and rich free space, but also accelerate the lithium-ions diffusion by virtue of its open tunnel-like architecture. Carbon 25-31 strawberry notch homolog 1 Homo sapiens 179-182 29972260-1 2018 Post-assembly reaction of a dynamic covalent iminoboronate system following addition of Cp2 Co resulted in the formation of a series of new reductively coupled dianionic dimers via C-C bond formation. Carbon 92-93 ceruloplasmin Homo sapiens 88-91 34198142-2 2021 The well-designed porous carbon coating offers an attractive advantage compared to the common carbon coatings, namely, it can not only better mitigate the volumetric variation of SnO2 by means of its spongy structure with better flexibility and rich free space, but also accelerate the lithium-ions diffusion by virtue of its open tunnel-like architecture. Carbon 94-100 strawberry notch homolog 1 Homo sapiens 179-182 26311303-1 2015 A facile unipolar pulse electrodeposition combined with the thermal oxidation method was applied for fabrication of CuO/Co3O4 composites on carbon electrode for water electrolysis, and it was found that the sea anemone-like one with a 3D hierarchical structure formed at -0.8 V exhibited excellent performance for water electrolysis at a low overpotential with high stability. Carbon 140-146 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 207-210 34771400-2 2021 A thin coat of carbon fiber wraps around the internal GFRP bars to improve the durability of internal GFRP bars in harsh environments. Carbon 15-21 GTP cyclohydrolase I feedback regulator Homo sapiens 54-58 26389552-1 2015 Surface carbon coating to improve the inherent poor electrical conductivity of lithium iron phosphate (LiFePO4, LFP) has been considered as most efficient strategy. Carbon 8-14 lamin A/C Homo sapiens 112-115 26389552-5 2015 This conformal carbon coating approach can be a promising strategy for the commercialization of LFP cathode in lithium ion batteries. Carbon 15-21 lamin A/C Homo sapiens 96-99 29973048-2 2018 Herein, we report a ratiometric fluorescent bioprobe based on DNA-labeled carbon dots (DNA-CDs) and 5,7-dinitro-2-sulfo-acridone (DSA) coupling with the target-catalyzing signal amplification for the detection of exosomal miRNA-21. Carbon 74-80 microRNA 21 Homo sapiens 222-230 29621646-3 2018 Modified glassy carbon electrode of N-CQD/Cu2O/GCE is developed and is used for the sensor studies of aspirin. Carbon 16-22 guanylate cyclase 2E, pseudogene Homo sapiens 47-50 34771400-2 2021 A thin coat of carbon fiber wraps around the internal GFRP bars to improve the durability of internal GFRP bars in harsh environments. Carbon 15-21 GTP cyclohydrolase I feedback regulator Homo sapiens 102-106 34731422-8 2022 The conductivity of AC enhanced the effect of EP, thereby cracking the sludge flocs. Carbon 20-22 epiregulin Homo sapiens 46-48 26133472-4 2015 An AR material with a low H/C ratio promoted the formation of CO2 and HCN, but suppressed the yields of NH3 and CH4. Carbon 28-29 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 70-73 34662099-12 2021 The observed switch in substrate specificity of the enzyme is consistent with this result if the hydrogen bonding to the proximal peroxo oxygen is necessary for a proposed nucleophilic peroxoanion-mediated mechanism for CYP17A1 in carbon-carbon bond scission. Carbon 231-237 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 220-227 26147366-8 2015 Also, IDO or TRP altered the expression of enzymes that control the availability of carbon atoms for FA synthesis, such as lactate dehydrogenase-A, pyruvate dehydrogenase, glutaminase 1 and glutaminase 2, in a way that inhibits FA synthesis. Carbon 84-90 indoleamine 2,3-dioxygenase 1 Homo sapiens 6-9 26269242-1 2015 BACKGROUND: Dihydrofolate reductase (DHFR) is essential for the conversion of folic acid to active folate needed for one-carbon metabolism. Carbon 121-127 dihydrofolate reductase Homo sapiens 12-35 30288153-5 2018 ITK is an open source C++ toolkit that has been actively developed over the past 18 years and is widely used by the medical image analysis community. Carbon 22-25 IL2 inducible T cell kinase Homo sapiens 0-3 29752099-1 2018 Our aim was to develop multiwalled carbon nanotubes (MWCNTs)-based nanoconstructs for the codelivery of N-desmethyl tamoxifen (N-TAM) and a mild P-gp efflux inhibitor, i.e., quercetin (QT) to treat multiple drug resistant (MDR) cancer cells. Carbon 35-41 phosphoglycolate phosphatase Homo sapiens 145-149 26269242-1 2015 BACKGROUND: Dihydrofolate reductase (DHFR) is essential for the conversion of folic acid to active folate needed for one-carbon metabolism. Carbon 121-127 dihydrofolate reductase Homo sapiens 37-41 34662099-12 2021 The observed switch in substrate specificity of the enzyme is consistent with this result if the hydrogen bonding to the proximal peroxo oxygen is necessary for a proposed nucleophilic peroxoanion-mediated mechanism for CYP17A1 in carbon-carbon bond scission. Carbon 238-244 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 220-227 29859293-0 2018 Carbon storage regulator CsrA plays important roles in multiple virulence-associated processes of Clostridium difficile. Carbon 0-6 carbon storage regulator CsrA Clostridioides difficile 630 25-29 34314548-9 2021 Third, while efforts designed to stimulate adoption of strategies allowing both emissions reduction (ER) and carbon sequestration (CS) would achieve the greatest net emissions mitigation, CS measures have greater potential mitigation and co-benefits. Carbon 109-115 citrate synthase Homo sapiens 131-133 29859293-1 2018 The carbon storage regulator CsrA is a global regulator that controls multiple virulence-associated processes including host cell invasion, virulence secretion, quorum sensing, biofilm formation, and motility in many pathogenic bacteria. Carbon 4-10 carbon storage regulator CsrA Clostridioides difficile 630 29-33 29859293-7 2018 Altogether, CsrA of C. difficile participates in multiple virulence processes including toxin production, motility, and adherence, and in the regulation of carbon metabolism. Carbon 156-162 carbon storage regulator CsrA Clostridioides difficile 630 12-16 26258871-3 2015 At 298 K and 1 bar, a very high selectivity for separating CO2/N2 (41.7) and CO2/CH4 (6.8) gas mixture pairs was obtained on the O-doped carbon activated with KOH at 600 C. The excellent separation ability of the O-doped carbons was demonstrated in transient breakthrough simulations of CO2/CH4/N2 mixtures in a fixed bed adsorber. Carbon 137-143 complement C2 Homo sapiens 59-65 26258871-3 2015 At 298 K and 1 bar, a very high selectivity for separating CO2/N2 (41.7) and CO2/CH4 (6.8) gas mixture pairs was obtained on the O-doped carbon activated with KOH at 600 C. The excellent separation ability of the O-doped carbons was demonstrated in transient breakthrough simulations of CO2/CH4/N2 mixtures in a fixed bed adsorber. Carbon 222-229 complement C2 Homo sapiens 59-65 33980350-0 2021 Application of Carbon Nanoparticle Tracers in the Lateral Neck Lymph Nodes of CN1bx Patients with Papillary Thyroid Carcinoma. Carbon 15-21 5'-nucleotidase, cytosolic IA Homo sapiens 78-81 26216667-5 2015 The values concerning CH-stretch overtones (nnu1) are similar to those found in the literature for HCN and C2H2, the molecules with sp-hybridized carbon atoms. Carbon 146-152 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 99-102 29960856-2 2018 It contributes to both central carbon metabolism and adipogenesis; specifically, through its role as the ATP-stimulated translocation promoter (ASTP). Carbon 31-37 glycerol kinase Rattus norvegicus 144-148 33980350-1 2021 This study aimed to investigate the applicability of carbon nanoparticle tracers in the lateral neck lymph nodes of CN1bx patients with papillary thyroid carcinoma surgery. Carbon 53-59 5'-nucleotidase, cytosolic IA Homo sapiens 116-119 30250920-1 2018 Isoform selection of pyruvate kinase M (PKM), a glycolytic enzyme, influences fates of glucose-derived carbons in cellular metabolic networks. Carbon 103-110 pyruvate kinase M1/2 Homo sapiens 21-38 30250920-1 2018 Isoform selection of pyruvate kinase M (PKM), a glycolytic enzyme, influences fates of glucose-derived carbons in cellular metabolic networks. Carbon 103-110 pyruvate kinase M1/2 Homo sapiens 40-43 25514355-1 2015 The global carbon cycle depends on the biological transformations of C1 compounds, which include the reductive incorporation of CO2into organic molecules (e.g. in photosynthesis and other autotrophic pathways), in addition to the production of CO2from formate, a reaction that is catalyzed by formate dehydrogenases (FDHs). Carbon 11-17 complement C2 Homo sapiens 128-131 34381282-3 2021 In this sense, with a layer of nickel hydroxide nanoparticles (Ni(OH)2 NPs), the screen-printed carbon electrode (SPCE) surface was directly electrodeposited to ensure better loading of spike protein on the surface of SPCE. Carbon 96-102 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 186-191 26205245-4 2015 This review describes effects of glucose repression on yeast carbon metabolism with a focus on roles of the Snf3/Rgt2 glucose-sensing pathway and Snf1 signal transduction in establishment and relief of glucose repression. Carbon 61-67 glucose sensor Saccharomyces cerevisiae S288C 113-117 25588806-8 2015 Moreover, multiple carbon metabolites including amino acids, organic acids, sugars, sugar alcohols, and aromatic amines were also positively regulated by AtPED2. Carbon 19-25 peroxin 14 Arabidopsis thaliana 154-160 25545348-12 2015 Moreover one metabolite resulting from cleavage of the side chain with subsequent oxidation of carbon at C17 was also detected. Carbon 95-101 cytokine like 1 Homo sapiens 105-108 30056511-0 2018 Carbon dots doped with nitrogen and boron as ultrasensitive fluorescent probes for determination of alpha-glucosidase activity and its inhibitors in water samples and living cells. Carbon 0-6 sucrase-isomaltase Homo sapiens 100-117 29554779-0 2018 Carbon burial and storage in tropical salt marshes under the influence of sea level rise. Carbon 0-6 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 74-77 34772058-0 2021 DFT-Based Studies on Carbon Adsorption on the wz-GaN Surfaces and the Influence of Point Defects on the Stability of the Diamond-GaN Interfaces. Carbon 21-27 gigaxonin Homo sapiens 49-52 34772058-0 2021 DFT-Based Studies on Carbon Adsorption on the wz-GaN Surfaces and the Influence of Point Defects on the Stability of the Diamond-GaN Interfaces. Carbon 21-27 gigaxonin Homo sapiens 129-132 25722172-1 2015 A new modified electrode was realized in a simple way, consisting by the immobilization of a myoglobin (My) - single walled carbon nanotubes (SWCNT) mixture on the surface of a graphite electrode with a Nafion film. Carbon 124-130 myoglobin Homo sapiens 93-102 34772058-5 2021 Following this, a model of diamond-GaN heterojunction with the growth direction (111) was constructed based on carbon adsorption results on GaN{0001} surfaces. Carbon 111-117 gigaxonin Homo sapiens 35-38 34772058-5 2021 Following this, a model of diamond-GaN heterojunction with the growth direction (111) was constructed based on carbon adsorption results on GaN{0001} surfaces. Carbon 111-117 gigaxonin Homo sapiens 140-143 29901386-2 2018 In this work, a simple one-pot template-free strategy for the preparation of three-dimensional hierarchical porous nitrogen-doped carbon framework in situ armored NiO nanograins (NCF/NiO) by an ammonia-induced method assisted by the pyrolysis of a decomposable salt is reported. Carbon 130-136 neutrophil cytosolic factor 4 Homo sapiens 179-182 34651161-5 2021 An experimental X-ray photoelectron spectroscopy study indicates that the chemical state of both molybdenum and carbon in Pt/beta-Mo2C are very different from those in the Pt-free carbide, which is also in agreement with the DFT results, which indicate that the Pt atoms generate a redistribution of charge density in their environment. Carbon 112-118 pre T cell antigen receptor alpha Homo sapiens 122-129 26141115-9 2015 RESULTS: Animals exposed to antigen in the presence of carbon nanoparticles showed increased effects with respect to ovalbumin sensitization, to the allergic airway inflammation after challenge, and to the specific TH2 response in the lymph nodes. Carbon 55-61 heart and neural crest derivatives expressed 2 Mus musculus 215-218 34587602-2 2021 Herein, a flexible integrated electrode consisting of SnS2 nanosheet arrays in-situ anchored on the functionalized carbon cloth was prepared via a facile one-step hydrothermal method. Carbon 115-121 sodium voltage-gated channel alpha subunit 11 Homo sapiens 54-58 34587602-3 2021 Through pretreatment of carbon cloth, rough morphology is appeared on the surface of carbon fiber, which is conducive to optimizing the accessible load of SnS2. Carbon 24-30 sodium voltage-gated channel alpha subunit 11 Homo sapiens 155-159 29579538-9 2018 The relationship between Kd and Koc for each site fitted into a quadratic model; it depicted a biphasic behavior of pesticide adsorption and desorption to sediments revealing that concentration of organic carbon across study sites was a limiting factor determining the extent of pesticide adsorption. Carbon 205-211 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 32-35 34587602-3 2021 Through pretreatment of carbon cloth, rough morphology is appeared on the surface of carbon fiber, which is conducive to optimizing the accessible load of SnS2. Carbon 85-91 sodium voltage-gated channel alpha subunit 11 Homo sapiens 155-159 25958246-1 2015 A (13)C-enriched phosphorylcholine polymer ((13)C-PMPC) as a self-traceable MR (magnetic resonance) tag was conjugated with a fragment (scFv) of Herceptin, a clinical antibody against antigen Her2. Carbon 6-7 erb-b2 receptor tyrosine kinase 2 Mus musculus 192-196 34380249-2 2021 Agricultural management practices are crucial to offset the anthropogenic C emission; hence, Carbon sequestration (CS) in agriculture is a viable option for reversing this cycle, but it is based on hypotheses that must be questioned in order to contribute to the development of new agricultural techniques. Carbon 93-99 citrate synthase Homo sapiens 115-117 26112740-7 2015 Promoters induced at low-glucose levels (P(HXT7), P(SSA1) and P(ADH2)) varied in induction strength on non-glucose carbon sources (sucrose, galactose and ethanol); in contrast to the "constitutive" promoters, GFP expression increased as glucose decreased and cells moved towards the diauxic shift. Carbon 115-121 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 64-68 34632994-4 2021 Using silica surfaces to limit the shrinkage of electrospun nanofibers during oxidation and carbonization, enhances the conversion of alcohol groups to normal carbonyl groups on the surface of the carbon wires derived from PAN fibers deposited with near field electrospinning (NFES). Carbon 197-203 adenosine deaminase 2 Homo sapiens 223-226 26196645-3 2015 A carbon nanotube is brought into close proximity to the emitter tip to act as an electrostatic biprism. Carbon 2-8 TOR signaling pathway regulator Homo sapiens 65-68 34101628-11 2021 IL-32beta/gamma/epsilon isoform mRNA were detected in HT-29 cells upon exposure to TNF-alpha, Poly I:C (TLR3 agonist), Flagellin (TLR-5 agonist) and HIV. Carbon 101-102 toll like receptor 3 Homo sapiens 104-108 26022322-1 2015 Due to high terrestrial runoff, the Baltic Sea is rich in dissolved organic carbon (DOC), the light-absorbing fraction of which is referred to as colored dissolved organic matter (CDOM). Carbon 76-82 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 43-46 34237228-2 2021 A new syndrome called "Shrunken Pore Syndrome" has been suggested, as the estimated glomerular filtration rate for cystatin C (eGFRcystatin C) is affected earlier due to differences in molecular size compared to eGFRcreatinine. Carbon 140-141 cystatin C Homo sapiens 115-125 26601368-0 2015 [SERS Enhancement Factor Analysis and Experiment of Carbon Nanotube Arrays Coated by Ag Nanoparticles]. Carbon 52-58 seryl-tRNA synthetase 1 Homo sapiens 1-5 34492331-5 2021 Based on RNA-seq data of Lewis lung cancer in C57BL/6 mice, carbon ion irradiation was found to significantly induce Klrk1 gene expression and activate the NKG2D/NKG2D-Ls pathway. Carbon 60-66 killer cell lectin-like receptor subfamily K, member 1 Mus musculus 117-122 25863370-1 2015 Electrochemical oxidation of adsorbed benzo(a)pyrene (BaP) on the glassy carbon electrode (GCE) was explored in acetonitrile-water. Carbon 73-79 prohibitin 2 Homo sapiens 54-57 34492331-5 2021 Based on RNA-seq data of Lewis lung cancer in C57BL/6 mice, carbon ion irradiation was found to significantly induce Klrk1 gene expression and activate the NKG2D/NKG2D-Ls pathway. Carbon 60-66 killer cell lectin-like receptor subfamily K, member 1 Mus musculus 156-161 34492331-5 2021 Based on RNA-seq data of Lewis lung cancer in C57BL/6 mice, carbon ion irradiation was found to significantly induce Klrk1 gene expression and activate the NKG2D/NKG2D-Ls pathway. Carbon 60-66 killer cell lectin-like receptor subfamily K, member 1 Mus musculus 162-167 34471141-3 2021 By integration of transcriptome, chromatin immunoprecipitation sequencing (CHIP-seq), Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq), proteomic and metabolite screening followed by carbon tracing and extracellular flux analyses we show that genetic and pharmacological AURKA inhibition elicits metabolic reprogramming mediated by inhibition of MYC targets and concomitant activation of Peroxisome Proliferator Activated Receptor Alpha (PPARA) signaling. Carbon 199-205 aurora kinase A Homo sapiens 287-292 25980580-5 2015 A mitochondria toxicity-screening modality confirmed a severe inability of IDH1-mutated cells to use various carbon substrates that are fed into the electron transport chain at different points. Carbon 109-115 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 75-79 25980580-6 2015 The mitochondrial biguanide poisons, metformin and phenformin, further impaired the intrinsic weakness of IDH1-mutant cells to use certain carbon-energy sources. Carbon 139-145 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 106-110 34355562-4 2021 Compounds 7, 8, 10, and 11 exhibited cytotoxicity to human cancer cell lines, indicating that the presence of a lactone moiety, as well as a double bond between C-22 and C-23, might play key roles in mediating their cytotoxicity. Carbon 161-162 nucleolin Homo sapiens 170-174 34707449-5 2021 The carbon dioxide adsorption uptakes of the obtained porous carbons were determined at 1 bar and 273 K. The templated carbon obtained with the lowest TEOS molar ratio exhibited the highest BET surface area of 1289 m2/g and micropore volume of 0.467 cm3/g, and showed the highest CO2 uptake of 2.28 mmol/g. Carbon 61-68 delta/notch like EGF repeat containing Homo sapiens 190-193 34707449-5 2021 The carbon dioxide adsorption uptakes of the obtained porous carbons were determined at 1 bar and 273 K. The templated carbon obtained with the lowest TEOS molar ratio exhibited the highest BET surface area of 1289 m2/g and micropore volume of 0.467 cm3/g, and showed the highest CO2 uptake of 2.28 mmol/g. Carbon 119-125 delta/notch like EGF repeat containing Homo sapiens 190-193 34165920-3 2021 The sulfur-carbon electrode exhibits in lithium half-cell a maximum capacity higher than 1200 mAh gS-1 , reversible electrochemical process, limited electrode/electrolyte interphase resistance, and a rate capability up to C/2. Carbon 11-17 pseudouridine 5'-phosphatase Homo sapiens 98-102 34416676-2 2021 The morphology and structure of the FA magnetic carbon nanotubes-molecularly imprinted polymers (MCNTs@FA-MIPs) were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, and X-ray diffraction. Carbon 48-54 glycogen synthase kinase 3 beta Rattus norvegicus 103-105 34250527-1 2021 Transketolase (TK) is a fundamentally important enzyme in industrial biocatalysis which carries out a stereospecific carbon-carbon bond formation, and is widely used in the synthesis of prochiral ketones. Carbon 117-123 transketolase Thermotoga maritima MSB8 0-13 34250527-1 2021 Transketolase (TK) is a fundamentally important enzyme in industrial biocatalysis which carries out a stereospecific carbon-carbon bond formation, and is widely used in the synthesis of prochiral ketones. Carbon 117-123 transketolase Thermotoga maritima MSB8 15-17 34250527-1 2021 Transketolase (TK) is a fundamentally important enzyme in industrial biocatalysis which carries out a stereospecific carbon-carbon bond formation, and is widely used in the synthesis of prochiral ketones. Carbon 124-130 transketolase Thermotoga maritima MSB8 0-13 34250527-1 2021 Transketolase (TK) is a fundamentally important enzyme in industrial biocatalysis which carries out a stereospecific carbon-carbon bond formation, and is widely used in the synthesis of prochiral ketones. Carbon 124-130 transketolase Thermotoga maritima MSB8 15-17 34145746-0 2021 Graphitic Carbon with MnO/Mn7 C3 Prepared by Laser-Scribing of MOF for Versatile Supercapacitor Electrodes. Carbon 10-16 lysine acetyltransferase 8 Homo sapiens 63-66 34145746-2 2021 Here, via simple laser-scribing, the Mn-based metal-organic framework (EG-MOF-74(Mn)) is transformed into pseudocapacitive hybrid MnO/Mn7 C3 encapsulated in highly conductive graphitic carbon. Carbon 185-191 lysine acetyltransferase 8 Homo sapiens 74-77 34205339-0 2021 Multi-Walled Carbon Nanotubes (MWCNTs) Cause Cellular Senescence in TGF-beta Stimulated Lung Epithelial Cells. Carbon 13-19 transforming growth factor alpha Homo sapiens 68-76 34145512-1 2021 Well-defined crystal structures of Pd-doped WO3 nanorods were assembled on graphitic carbon sheets (Pd-WO3/g-C3N4) for ultrasensitive detection of paraoxon-ethyl (PEL) using an electrochemical method. Carbon 85-91 phosphoglycerate dehydrogenase Homo sapiens 100-108 34204568-6 2021 The degradation of rubber first takes place when lcp enzyme cleaves the isoprene double bond, breaking them down into the sole carbon and energy source to be utilized by the bacteria. Carbon 127-133 kelch domain containing 2 Homo sapiens 49-52 34738134-3 2021 Also, several analyses such as SEM, FTIR, EDAX and BET were done to determine the surface properties of the activated carbon. Carbon 118-124 delta/notch like EGF repeat containing Homo sapiens 51-54 34072661-0 2021 Plastic Antibody of Polypyrrole/Multiwall Carbon Nanotubes on Screen-Printed Electrodes for Cystatin C Detection. Carbon 42-48 cystatin C Homo sapiens 92-102 34150282-2 2021 The surface properties of the activated carbon were investigated by elementary analysis, BET surface area, SEM, FTIR and pHpzc. Carbon 40-46 delta/notch like EGF repeat containing Homo sapiens 89-92 29792698-4 2018 Inherent factors that control site-selectivity are described along with mechanistically driven approaches for site-selective switching, where the C-+PPh3 group can be predictably installed at other positions in the polyazine system. Carbon 146-147 protein phosphatase 4 catalytic subunit Homo sapiens 149-153 34927885-4 2021 Herein, a facile way of preparing bimetallic Fe and Co sites entrapped in nitrogen-doped hollow carbon nanospheres (Fe,Co-SA/CS) is explored, drawing on the unique structure and pore characteristics of Zeolitic imidazole frameworks and molecular size of Ferrocene, an Fe containing species. Carbon 96-102 citrate synthase Homo sapiens 125-127 29951035-4 2018 Recent studies indicate that sterol 27-hydroxylase (CYP27A1) is an emerging antiatherogenic enzyme, that, by converting extrahepatic cholesterol to 27-hydroxycholesterol, facilitates cholesterol removal via high-density lipoprotein-cholesterol (HDL-C). Carbon 52-53 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 29-50 35636361-3 2022 This paper investigates the electrochemical determination of the mefenamic acid (MEF), with a novel carbon paste electrode modified with terbium titanate nanostructures (TTN/CPE). Carbon 100-106 titin Homo sapiens 170-173 29782802-4 2018 During the hydrogenation of 3-nitrostyrene, the TOF numbers based on surface Pt atoms of Pt1/Ni nanocrystals reached ~1800 h-1 under 3 atm of H2 at 40 C, much higher than that of Pt single atoms supported on active carbon, TiO2, SiO2, and ZSM-5. Carbon 216-222 zinc finger protein 77 Homo sapiens 89-92 35139227-3 2022 KEY FINDINGS: From AG-SM12-SD to AG-SM22-SD with the increase of the carbon chain length of carrier material, the glass transition temperature, the maximum relaxation enthalpy and the mean relaxation time of SD increased at first and then decreased; the isothermal crystallization rate constants at different temperatures and non-isothermal crystallization rate constants at different heating rates of SD showed a trend of decreasing at first and then increasing. Carbon 69-75 transgelin Homo sapiens 36-40 35535465-3 2022 Herein, a novel needlelike Co3O4/C array architecture is constructed from MOF precursor via a simple pyrolysis process, and its microstructure is controllably tailored by changing the pyrolysis temperature. Carbon 33-34 lysine acetyltransferase 8 Homo sapiens 74-77 29671434-0 2018 Rh(ii)/phosphine-cocatalyzed synthesis of dithioketal derivatives from diazo compounds through simultaneous construction of two different C-S bonds. Carbon 138-139 Rh blood group D antigen Homo sapiens 0-6 29671434-1 2018 Rhodium(ii)/phosphine-cocatalyzed bis-sulfuration of alpha-diazocarbonyl compounds using thiosulfonates as the sulfenylating agent, which provided two sulfur-containing moieties, was developed via simultaneous inter- and intra-molecular C-S bond formation. Carbon 237-238 Rh blood group D antigen Homo sapiens 8-10 29706565-4 2018 In particular, via GATA6, metastatic cells in the liver upregulate the enzyme aldolase B (ALDOB), which enhances fructose metabolism and provides fuel for major pathways of central carbon metabolism during tumor cell proliferation. Carbon 181-187 GATA binding protein 6 Homo sapiens 19-24 35579458-5 2022 We found the sinking of Trichodesmium into deep water was far more efficient than that of Prochlorococcus, suggesting Trichodesmium blooms might be an essential carbon and nitrogen source for the maintenance of the BoB OMZ. Carbon 161-167 G protein-coupled receptor 15 Homo sapiens 215-218 29341173-6 2018 Unlike the wild type plants, chilling-induced inhibition of photosynthetic carbon assimilation was observed in the rms lines and also in the Arabidopsis max3-9, max4-1, and max2-1 mutants that are defective in SL synthesis or signalling. Carbon 75-81 carotenoid cleavage dioxygenase 7 Arabidopsis thaliana 153-159 25461755-1 2015 A new uric acid biosensor was constructed using ferrocene (Fc) induced electro-activated uricase (UOx) deposited within Nafion (Naf) on glassy carbon electrode (GCE). Carbon 143-149 aminomethyltransferase Homo sapiens 161-164 35579458-14 2022 This study highlighted that Trichodesmium might be an essential carbon and nitrogen source in the maintenance of the BoB OMZ. Carbon 64-70 G protein-coupled receptor 15 Homo sapiens 117-120 25672970-5 2015 We demonstrated that C-30-27 selectively inhibited acetylation-dependent nuclear factor-kappaB (NF-kappaB) at Lys-122 and suppressed the NF-kappaB-mediated inflammatory response induced by lipopolysaccharide (LPS) or Abeta in both BV2 and Neuro-2A (N2A) cells. Carbon 21-22 amyloid beta (A4) precursor protein Mus musculus 217-222 25828701-6 2015 TRAF6 is determined to be a direct E3 ligase for GSK3beta, and TRAF6-mediated GSK3beta ubiquitination is essential for poly I:C-dependent cytokine production by promoting the TLR3 adaptor protein TRIF-assembled signalling complex. Carbon 126-127 TNF receptor associated factor 6 Homo sapiens 0-5 29761202-5 2018 Using ab initio calculations, here we show that the most stable structure of a DNT is composed of alternative SW and hydrogenated carbon nanotube (3,0) units, suggesting that SW plays an essential role in stabilizing DNT. Carbon 130-136 5', 3'-nucleotidase, cytosolic Homo sapiens 79-82 29761202-5 2018 Using ab initio calculations, here we show that the most stable structure of a DNT is composed of alternative SW and hydrogenated carbon nanotube (3,0) units, suggesting that SW plays an essential role in stabilizing DNT. Carbon 130-136 5', 3'-nucleotidase, cytosolic Homo sapiens 217-220 25828701-6 2015 TRAF6 is determined to be a direct E3 ligase for GSK3beta, and TRAF6-mediated GSK3beta ubiquitination is essential for poly I:C-dependent cytokine production by promoting the TLR3 adaptor protein TRIF-assembled signalling complex. Carbon 126-127 TNF receptor associated factor 6 Homo sapiens 63-68 35533403-4 2022 For p-BQ, the nucleophilic attack of HO2-, CH3OO-, PMS, and PAA might prefer to occur on the carbonyl carbons, which have more positive atomic charges. Carbon 102-109 heme oxygenase 2 Homo sapiens 37-40 35510663-10 2022 Furthermore, poly I:C upregulates TLR3 (SMD = 0.64; CIs (0.56, 0.72); p = 0.00), downregulates nuclear factor-kappaB (NF-kappaB) (SMD = -1.78; CIs (-2.67, -0.88); p = 0.0)), and tumor necrosis factor alpha (TNF-alpha) (SMD = -16.83; CIs (-22.63, -11.02); p = 0.00). Carbon 20-21 toll like receptor 3 Homo sapiens 34-38 35510663-13 2022 Further research on simultaneous activation of TLR3 with poly I:C and suppression of TLR 2/4 might open new vistas for the development of therapeutics against CI. Carbon 64-65 toll like receptor 3 Homo sapiens 47-51 29789642-0 2018 Spatial and temporal variations of particulate organic carbon in the Yellow-Bohai Sea over 2002-2016. Carbon 55-61 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 82-85 35411903-1 2022 Blending polyacrylonitrile (PAN) with plastic wastes and bio-based polymers provides a convenient and inexpensive method to realize cost-effective carbon fiber (CF) precursors. Carbon 147-153 adenosine deaminase 2 Homo sapiens 28-31 25528228-3 2015 Experimental results demonstrated that E1, E2 and EE2 were effectively removed through electro-polymerization on the granular glassy carbon (and Pt/Ti) anode counter. Carbon 133-139 small nucleolar RNA, H/ACA box 73A Homo sapiens 39-53 35411903-2 2022 In this work, PAN-based blend precursors are investigated using ReaxFF reactive molecular dynamics simulations with respect to the formation of all-carbon rings, the evolutions of oxygen-containing and nitrogen-containing species, and the migration of carbon atoms to form turbostratic graphene. Carbon 148-154 adenosine deaminase 2 Homo sapiens 14-17 29501129-0 2018 Electrochemical quantum dots-based magneto-immunoassay for detection of HE4 protein on metal film-modified screen-printed carbon electrodes. Carbon 122-128 WAP four-disulfide core domain 2 Homo sapiens 72-75 35411903-2 2022 In this work, PAN-based blend precursors are investigated using ReaxFF reactive molecular dynamics simulations with respect to the formation of all-carbon rings, the evolutions of oxygen-containing and nitrogen-containing species, and the migration of carbon atoms to form turbostratic graphene. Carbon 252-258 adenosine deaminase 2 Homo sapiens 14-17 29501129-3 2018 Electrochemical detection of anti-HE4 IgG - HE4 - anti-HE4 IgGCdSe/ZnS immunocomplex was performed by recording the current response of Cd(II) ions, released from dissolved quantum dots at screen-printed carbon electrode (SPCE), modified with mercury or bismuth film. Carbon 204-210 WAP four-disulfide core domain 2 Homo sapiens 34-37 29501129-3 2018 Electrochemical detection of anti-HE4 IgG - HE4 - anti-HE4 IgGCdSe/ZnS immunocomplex was performed by recording the current response of Cd(II) ions, released from dissolved quantum dots at screen-printed carbon electrode (SPCE), modified with mercury or bismuth film. Carbon 204-210 WAP four-disulfide core domain 2 Homo sapiens 44-47 25769345-7 2015 Genes co-regulated between the CR and ade4 conditions were dominated by GO terms related to metabolism of alternative carbon sources, consistent with chronological longevity requiring efficient acetate/acetic acid utilization. Carbon 119-125 amidophosphoribosyltransferase Saccharomyces cerevisiae S288C 38-42 29501129-3 2018 Electrochemical detection of anti-HE4 IgG - HE4 - anti-HE4 IgGCdSe/ZnS immunocomplex was performed by recording the current response of Cd(II) ions, released from dissolved quantum dots at screen-printed carbon electrode (SPCE), modified with mercury or bismuth film. Carbon 204-210 WAP four-disulfide core domain 2 Homo sapiens 44-47 35446532-3 2022 Here, we report the development of an electrochemical sensing platform based on single-walled carbon nanotube screen-printed electrodes (SWCNT-SPEs) functionalized with a redox-tagged DNA aptamer that specifically binds to the receptor binding domain of the SARS-CoV-2 spike protein S1 subunit. Carbon 94-100 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 269-274 29762494-1 2018 A simple and easy method was implemented for the contemporary detection of cadmium (Cd2+) and lead (Pb2+) ions using 1,3,6,8-pyrenetetrasulfonic acid sodium salt-functionalized carbon nanotubes nanocomposites (PyTS-CNTs). Carbon 177-183 CD2 molecule Homo sapiens 84-87 25395450-9 2015 This is an initial demonstration that supplementation along the one-carbon pathway abrogates adult morbidity and associated epigenomic modifications of IGF-1 in a rodent model of multigenerational MetS. Carbon 68-74 insulin-like growth factor 1 Rattus norvegicus 152-157 35394270-5 2022 The relative percentages of CS/WP-VOCs were higher than those of SBC-VOCs, and most VOCs tended to have relatively small carbon skeletons as the average carbon oxidation state increased. Carbon 153-159 citrate synthase Homo sapiens 28-33 24662817-10 2015 GLO1 downregulation affected cell growth through inactivating central carbon metabolism and reduced the transcriptional activities of nuclear factor kappa B and activator protein-1. Carbon 70-76 glyoxalase I Homo sapiens 0-4 25567721-5 2015 X-ray absorption spectra exhibit an increasing number of unoccupied 3d states and a decreasing number of C 2p states as a function of carbon content. Carbon 134-140 complement C2 Homo sapiens 105-109 29659263-4 2018 Structures 3 contain an unusual weak eta1-C anagostic interaction involving the rhodium atom and one carbon atom of the olefinic C-H bond of the norbornenyl substituent in the chelating quinolinyl-hydroxyalkyl moiety. Carbon 101-107 secreted phosphoprotein 1 Homo sapiens 37-41 35212125-5 2022 Moreover, the MOF/ bacterial cellulose composite sponge reported here showed a nearly 8-fold enhancement in the protection against an ultra-toxic nerve agent (GD) in permeability studies as compared to a commercialized adsorptive carbon cloth. Carbon 230-236 lysine acetyltransferase 8 Homo sapiens 14-17 29644361-1 2018 We herein report the preparation of unique heteroatom-doped and carbon-based AuAg alloy nanoparticles (NPs) via the pyrolysis of a structurally defined octanuclear heterometallic Au(i)-Ag(i) cluster [Au4Ag4(Dppy)4(Tab)4(MeCN)4](PF6)8 (2, Dppy = diphenylphosphine-2-pyridine and Tab = 4-(trimethylammonio)benzenethiolate). Carbon 64-70 dipeptidyl peptidase like 10 Homo sapiens 207-211 29644361-1 2018 We herein report the preparation of unique heteroatom-doped and carbon-based AuAg alloy nanoparticles (NPs) via the pyrolysis of a structurally defined octanuclear heterometallic Au(i)-Ag(i) cluster [Au4Ag4(Dppy)4(Tab)4(MeCN)4](PF6)8 (2, Dppy = diphenylphosphine-2-pyridine and Tab = 4-(trimethylammonio)benzenethiolate). Carbon 64-70 dipeptidyl peptidase like 10 Homo sapiens 238-242 29645054-3 2018 To increase the stability of the ArSb complexes, in particular those containing Pd(ii), the simple auxiliary ligands were replaced with C,N-chelating ones, which led to a set of four compounds of the type [RMCl(ArSb)], where R = C6H4-2-(CH2NMe2) or Fe(eta5-C5H4)(eta5-C5H3-2-(CH2NMe2)) and M = Pd (3, 5) or Pt (4, 6). Carbon 136-137 arylsulfatase B Homo sapiens 33-37 25490879-3 2015 In the process, the indole unit of L1 is deprotonated by the metal alkyl species and the imino C=N group is transferred to the amido group by alkyl CH2 SiMe3 insertion, affording a new dianionic ligand that bridges two metal alkyl units in mu-eta(2) :eta(1) :eta(1) bonding modes, forming the dinuclear rare-earth metal alkyl complexes. Carbon 95-96 secreted phosphoprotein 1 Homo sapiens 251-257 25490879-3 2015 In the process, the indole unit of L1 is deprotonated by the metal alkyl species and the imino C=N group is transferred to the amido group by alkyl CH2 SiMe3 insertion, affording a new dianionic ligand that bridges two metal alkyl units in mu-eta(2) :eta(1) :eta(1) bonding modes, forming the dinuclear rare-earth metal alkyl complexes. Carbon 95-96 secreted phosphoprotein 1 Homo sapiens 259-265 25495051-6 2015 GRMZM2G393334 encodes a putative folylpolyglutamate synthase (FPGS), which functions in one-carbon (C1) metabolism to polyglutamylate substrates of folate-dependent enzymes. Carbon 92-98 folylpolyglutamate synthase Zea mays 33-60 25495051-6 2015 GRMZM2G393334 encodes a putative folylpolyglutamate synthase (FPGS), which functions in one-carbon (C1) metabolism to polyglutamylate substrates of folate-dependent enzymes. Carbon 92-98 folylpolyglutamate synthase Zea mays 62-66 35196069-5 2022 Transcriptome-wide analysis revealed a coordinated regulation of metabolic enzymes related to one-carbon metabolism, including three methyltransferase enzymes (KMT2D, SETD1B, and ASH1L), key enzymes for both carnitine synthesis and histone modification. Carbon 98-104 ASH1 like histone lysine methyltransferase Homo sapiens 179-184 29740575-5 2018 Compounds AntiOxBEN1 and 15, with a shorter carbon chain spacer (six- and eight-carbon) were shown to be potent antioxidants and BChE inhibitors (IC50 = 85 +- 5 and 106 +- 5 nM, respectively), while compounds 17 and 18 with a 10-carbon chain were more effective AChE inhibitors (IC50 = 7.7 +- 0.4 and 7.2 +- 0.5 muM, respectively). Carbon 80-86 butyrylcholinesterase Homo sapiens 129-133 29740575-5 2018 Compounds AntiOxBEN1 and 15, with a shorter carbon chain spacer (six- and eight-carbon) were shown to be potent antioxidants and BChE inhibitors (IC50 = 85 +- 5 and 106 +- 5 nM, respectively), while compounds 17 and 18 with a 10-carbon chain were more effective AChE inhibitors (IC50 = 7.7 +- 0.4 and 7.2 +- 0.5 muM, respectively). Carbon 80-86 butyrylcholinesterase Homo sapiens 129-133 25406399-3 2015 The latter isomerized via the addition of the phenyl radical to the terminal C1/C4 carbon atoms through submerged barriers forming resonantly stabilized free radicals C11H13, which then underwent cis-trans isomerization followed by ring closure. Carbon 83-89 heterogeneous nuclear ribonucleoprotein C Homo sapiens 77-82 29675469-4 2018 We engineered a prototype optical sensor composed of an antibody-functionalized carbon nanotube complex, which responds quantitatively to HE4 via modulation of the nanotube optical bandgap. Carbon 80-86 WAP four-disulfide core domain 2 Homo sapiens 138-141 35412316-7 2022 Two Er3+ ions in the mu2-bridge are stabilized by five-membered rings formed by chelating Er3+ with an O-C-C-O moiety. Carbon 105-106 adaptor related protein complex 1 subunit mu 2 Homo sapiens 21-24 29487229-3 2018 It appears that prokaryotic FAH superfamily members evolved mainly to allow microbes to generate energy and useful metabolites from complex carbon sources. Carbon 140-146 fumarylacetoacetate hydrolase Homo sapiens 28-31 29487229-5 2018 The identification of human FAH domain-containing protein 1 as mitochondrial ODx regulating mitochondrial function supports the new concept that, during evolution, eukaryotic FAH superfamily members have acquired important regulatory functions beyond catabolism of complex carbon sources. Carbon 273-279 fumarylacetoacetate hydrolase Homo sapiens 28-31 26165290-1 2015 A novel photoelectrochemical strategy for the sensitive determination of p-nitrophenol (PNP) was developed using a glassy carbon electrode (GCE) modified with CdSe quantum dots (QDs) and DNA composite film (CdSe-DNA/GCE). Carbon 122-128 guanylate cyclase 2E, pseudogene Homo sapiens 140-143 26700591-3 2015 Here, we show that a branched-chain C-20 polyunsaturated fatty acid, geranylgeranoic acid (GGA), induces upregulation of the cellular protein levels of TP53-induced glycolysis and apoptosis regulator (TIGAR) and synthesis of cytochrome c oxidase 2 (SCO2) in human hepatoma-derived HuH-7cells harboring the mutant TP53 gene, suggesting that GGA may shift an energetic state of the tumor cells from aerobic glycolysis to mitochondrial respiration. Carbon 36-37 synthesis of cytochrome C oxidase 2 Homo sapiens 249-253 29487229-5 2018 The identification of human FAH domain-containing protein 1 as mitochondrial ODx regulating mitochondrial function supports the new concept that, during evolution, eukaryotic FAH superfamily members have acquired important regulatory functions beyond catabolism of complex carbon sources. Carbon 273-279 fumarylacetoacetate hydrolase Homo sapiens 175-178 29494148-1 2018 The structure-activity relationship was investigated in a series of synthetic TLR4 antagonists formed by a glucosamine core linked to two phosphate esters and two linear carbon chains. Carbon 170-176 toll like receptor 4 Homo sapiens 78-82 25355806-9 2015 Furthermore, TLR3 signalling pathway components, including NF-kappaB and IL-6/TNFalpha, were markedly upregulated upon stimulation with poly(I:C). Carbon 143-144 toll-like receptor 3 Rattus norvegicus 13-17 35412316-7 2022 Two Er3+ ions in the mu2-bridge are stabilized by five-membered rings formed by chelating Er3+ with an O-C-C-O moiety. Carbon 107-108 adaptor related protein complex 1 subunit mu 2 Homo sapiens 21-24 25464279-3 2015 However, an obvious peak under 100gCl/kg of PSSA appeared for Cu, owing to the presence of carbon and hydrogen in PVC. Carbon 91-97 phosphatidylserine synthase 1 Homo sapiens 44-48 35563000-1 2022 The mitochondrial carnitine/acylcarnitine carrier (CAC) transports short-, medium- and long-carbon chain acylcarnitines across the mitochondrial inner membrane in exchange for carnitine. Carbon 92-98 solute carrier family 25 member 20 Homo sapiens 51-54 29494148-2 2018 Molecular modeling showed that the compounds with 10, 12, and 14 carbons chains are associated with higher stabilization of the MD-2/TLR4 antagonist conformation than in the case of the C16 variant. Carbon 65-72 toll like receptor 4 Homo sapiens 133-137 25046268-6 2015 Preventing PCSK9-mediated LDL receptor degradation with monoclonal antibodies is a novel strategy to further lower LDL-C, especially in patients with severe forms of hypercholesterolemia with elevated LDL-C despite maximal conventional treatment and/or in those intolerant to conventional therapies. Carbon 12-13 low density lipoprotein receptor Homo sapiens 26-38 35345880-16 2022 For molecular ion swimmers that contain 10 to 14 carbon atom alkyl linkers, they all turn out to be highly active (EC50 = 0.18-0.41 mol %) and highly selective (RK+/RNa+ = 7.0-9.5) transporters. Carbon 49-55 ribokinase Homo sapiens 161-163 25355315-3 2014 Transcription activation of both sets is regulated positively by the yeast AMP-activated protein kinase homolog, Snf1, in response to low glucose or the presence of a non-fermentable carbon source and negatively by two redundant 14-3-3 isoforms, Bmh1 and Bmh2. Carbon 183-189 14-3-3 family protein BMH2 Saccharomyces cerevisiae S288C 255-259 29151585-5 2018 Next, this pro-T-cell system was used to demonstrate that ectopic expression of the TAL1 transcription factor and Pten deletion are bona-fide cooperating events resulting in an increased stem cell signature, upregulation of a specific E2f signaling network and metabolic reprogramming with higher influx of glucose carbons into the tricarboxylic acid cycle. Carbon 315-322 TAL bHLH transcription factor 1, erythroid differentiation factor Homo sapiens 84-88 29151585-5 2018 Next, this pro-T-cell system was used to demonstrate that ectopic expression of the TAL1 transcription factor and Pten deletion are bona-fide cooperating events resulting in an increased stem cell signature, upregulation of a specific E2f signaling network and metabolic reprogramming with higher influx of glucose carbons into the tricarboxylic acid cycle. Carbon 315-322 phosphatase and tensin homolog Homo sapiens 114-118 35440542-5 2022 Nicotinamide N-methyltransferase (NNMT), a one-carbon metabolic enzyme, is identified as a potential marker of ccRCC and a drug target for GP1. Carbon 47-53 nicotinamide N-methyltransferase Homo sapiens 0-32 35440542-5 2022 Nicotinamide N-methyltransferase (NNMT), a one-carbon metabolic enzyme, is identified as a potential marker of ccRCC and a drug target for GP1. Carbon 47-53 nicotinamide N-methyltransferase Homo sapiens 34-38 25425668-6 2014 MAX1 catalyzed consecutive oxidations at C-19 of CL to convert the C-19 methyl group into carboxylic acid, 9-desmethyl-9-carboxy-CL [designated as carlactonoic acid (CLA)]. Carbon 41-42 cytochrome P450, family 711, subfamily A, polypeptide 1 Arabidopsis thaliana 0-4 35377117-1 2022 In the present work, the degradation of methylene blue (MB) was investigated by electron beam irradiation combined with graphite carbon nitride/carbon nanodots (EBI&g-C3N4/CDs). Carbon 144-150 transducin beta like 1 X-linked Homo sapiens 161-164 25671108-0 2014 Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism. Carbon 95-101 aminoadipate-semialdehyde synthase Mus musculus 0-23 25387795-0 2014 A rare tetranuclear thorium(IV) mu4 -oxo cluster and dinuclear thorium(IV) complex assembled by carbon-oxygen bond activation of 1,2-dimethoxyethane (DME). Carbon 96-102 adaptor related protein complex 4 subunit mu 1 Homo sapiens 32-35 29575578-1 2018 Dip pen nanolithography (DPN) is used to pattern single-walled carbon nanotube (SWCNT) lines between the n-type Si and SWCNT film in SWCNT/Si solar cells. Carbon 63-69 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 4-7 29546901-1 2018 A new two-dimensional (2D) carbon allotrope, Hexa-C20, composed of C20 fullerene is proposed. Carbon 27-33 hexosaminidase subunit alpha Homo sapiens 45-49 29272560-2 2018 Two classes of beta residue have been widely explored in the context of generating alpha-helix-like conformations: beta3 -amino acids, which are homologous to alpha-amino acids and bear a side chain on the backbone carbon adjacent to nitrogen, and residues constrained by a five-membered ring, such the one derived from trans-2-aminocyclopentanecarboxylic acid (ACPC). Carbon 215-221 basic helix-loop-helix family member e22 Homo sapiens 115-120 35378390-0 2022 Carbon pathways during transitory starch degradation in Arabidopsis differentially affect the starch granule number and morphology in the dpe2/phs1 mutant background. Carbon 0-6 dual specificity protein phosphatase family protein Arabidopsis thaliana 143-147 29126942-1 2018 A simple electrochemical DNA- based biosensor was designed for determination of Cd2+ using ethyl green (EG) as a DNA hybridization indicator on the surface of carbon paste electrode (CPE). Carbon 159-165 CD2 molecule Homo sapiens 80-83 25277226-5 2014 The study of two distinct D-gluco and L-ido stereochemistries for the tetrol pattern as well as R and S configurations for the C-2 carbon bearing the C-alkyl chain is reported. Carbon 131-137 complement C2 Homo sapiens 127-130 25333339-1 2014 A P(NMe2)3-mediated reductive cyclopropanation reaction of alpha-keto esters or amides with isatin-derived alkenes has been developed, providing efficient and diastereoselective synthesis of highly functionalized spirocyclopropyl oxindoles bearing two all-carbon quaternary centers. Carbon 256-262 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 4-8 35229094-3 2022 Furthermore, a Sc(OTf)3/chiral N,N"-dioxide catalyzed asymmetric Michael addition of benzofuranone to MVK has been optimized for forging a chiral aromatic quaternary carbon center, which enables the formal synthesis of (+)-ent-herbertenolide. Carbon 166-172 mevalonate kinase Homo sapiens 102-105 25316343-2 2014 The computational screening of reactions for different hydrocarbons (CH4, C2H6, C3H8, C2H4, and C2H2) as readily available carbon precursors for HCN formation, potential chemical transport agents, and for controlled carbon doping of deposited GaN was carried out with the B3LYP method in conjunction with basis sets up to aug-cc-pVTZ. Carbon 60-66 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 145-148 29313666-4 2018 Previous studies suggest that carbon-1 galactose derivatives show diminished binding since the hydroxyl group in the carbon-1 position of the sugar is a hydrogen bond acceptor in the galectin-1 sugar binding site. Carbon 30-36 galectin 1 Homo sapiens 183-193 29313666-9 2018 Compared to that of the carbon-1 conjugate, the uptake of the carbon-3 conjugate was greater in cell lines containing high expression levels of galectin-1. Carbon 24-30 galectin 1 Homo sapiens 144-154 25316343-2 2014 The computational screening of reactions for different hydrocarbons (CH4, C2H6, C3H8, C2H4, and C2H2) as readily available carbon precursors for HCN formation, potential chemical transport agents, and for controlled carbon doping of deposited GaN was carried out with the B3LYP method in conjunction with basis sets up to aug-cc-pVTZ. Carbon 123-129 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 145-148 35296702-6 2022 This variant explains the FBP- or FBPase-related findings more easily than the canonical CB cycle as well as the dependency of photosynthetic carbon metabolism on SBPase and further suggests that co-overexpression of SBPase and transaldolase can be a strategy for enhancing photosynthetic carbon metabolism, which is important for the global environment. Carbon 289-295 Inositol monophosphatase family protein Arabidopsis thaliana 26-29 24952994-3 2014 The 18-carbon acyl chain length ceramide species was associated with AbetaX-38 (r = 0.312, p = 0.003), AbetaX-40 (r = 0.327, p = 0.002), and T-tau (r = 0.313, p = 0.003) but not with AbetaX-42 (r = 0.171, p = 0.106) or p-tau (r = 0.086, p = 0.418). Carbon 7-13 microtubule associated protein tau Homo sapiens 143-146 24952994-3 2014 The 18-carbon acyl chain length ceramide species was associated with AbetaX-38 (r = 0.312, p = 0.003), AbetaX-40 (r = 0.327, p = 0.002), and T-tau (r = 0.313, p = 0.003) but not with AbetaX-42 (r = 0.171, p = 0.106) or p-tau (r = 0.086, p = 0.418). Carbon 7-13 microtubule associated protein tau Homo sapiens 221-224 35232977-8 2022 Finally, we observed that RP5-998N21.4OE can enhance IFIT2- and IFIT3-mediated immune defense responses through activation of signal transducer and activator of transcription 1 (STAT1) signaling pathway in U251 astrocytoma cells under treatment with the viral mimetic polyinosinic: polycytidylic acid (poly I:C). Carbon 309-310 interferon induced protein with tetratricopeptide repeats 2 Homo sapiens 53-58 24997373-1 2014 A fluidized bed membrane bioelectrochemical reactor (MBER) was investigated using fluidized granular activated carbon (GAC) as a mean of membrane fouling control. Carbon 111-117 glutaminase Homo sapiens 119-122 25047936-1 2014 Selective and nanomolar acetylcholinesterase inhibitors were obtained by connecting tri- and tetracyclic quinazolinones-previously described as moderately active and unselective cholinesterase (ChE) inhibitors-via a hydroxyl group in para position to an anilinic nitrogen with different amines linked via a three carbon atom spacer. Carbon 313-319 butyrylcholinesterase Homo sapiens 30-44 29031228-4 2018 In this work, a novel biosensor for detecting juvenile idiopathic arthritis (JIA) was developed based on the immobilization of the PRF+1 mimetic peptide, as recognition biological element, on the surface of screen-printed carbon electrode. Carbon 222-228 perforin 1 Homo sapiens 131-136 29279115-1 2018 Simultaneous determination of Cd2+ and Pb2+ was achieved by using graphene oxide/kappa-carrageenan/l-cysteine (GO/kappa-Car/l-Cys) nanocomposite modified glassy carbon electrode (GCE) by Square Wave Anodic Stripping Voltammetry (SWASV). Carbon 161-167 CD2 molecule Homo sapiens 30-33 35297184-3 2022 Detailed XPS spectra and DFT calculations confirm the formation of carbon-iron bonds in HNG-ethanol during synthesis process, which act as electron transport channels from graphene to Hemin. Carbon 67-73 neurogranin Homo sapiens 88-91 25924408-2 2014 The dechlorination of CCl4 to dichloromethane (CH2Cl2) and chloroform (CHCl3) with a molar ratio of 3:2 was catalyzed by carbon-supported silver (Ag/C) catalyst in methanol solution. Carbon 121-127 C-C motif chemokine ligand 4 Homo sapiens 22-26 34999315-3 2022 This research investigates the removal of DOM and the minimization of DBP formation by pilot-scale coal- and coconut-based granular activated carbon filtrations (coAC and ccAC, respectively) using unknown screening analysis with Orbitrap mass spectrometry. Carbon 142-148 phosphopantothenoylcysteine decarboxylase Homo sapiens 162-166 28611470-3 2018 A radical-polar crossover reaction between an AE-ring radical precursor, a C-ring radical acceptor and an aldehyde was realized by the actions of Et3B and O2, resulting in the installation of three new stereocenters and extension of the carbon chain corresponding to the B-ring. Carbon 237-243 CBFA2/RUNX1 partner transcriptional co-repressor 3 Homo sapiens 146-157 29338617-0 2018 Carbon nanospheres mediated nuclear delivery of SMAR1 protein (DNA binding domain) controls breast tumor in mice model. Carbon 0-6 BTG3 associated nuclear protein Mus musculus 48-53 35267723-7 2022 Plates for flange joints were fabricated with carbon fiber FRP. Carbon 46-52 secreted frizzled related protein 1 Homo sapiens 59-62 29354815-0 2018 CoP nanoparticles anchored on N,P-dual-doped graphene-like carbon as a catalyst for water splitting in non-acidic media. Carbon 59-65 caspase recruitment domain family member 16 Homo sapiens 0-3 29354815-2 2018 CoP nanoparticles anchored on N,P-dual-doped mesoporous graphene-like carbon (CoP@NPMG) acts as an outstanding bifunctional electrocatalyst for both the hydrogen evolution reaction and the oxygen evolution reaction over a wide pH range. Carbon 70-76 caspase recruitment domain family member 16 Homo sapiens 0-3 25195850-1 2014 The fabrication of an electrochemical sensor based on an iron oxide/graphene modified glassy carbon electrode (Fe3O4/rGO/GCE) and its simultaneous detection of dopamine (DA) and ascorbic acid (AA) is described here. Carbon 93-99 guanylate cyclase 2E, pseudogene Homo sapiens 121-124 24657644-5 2014 At the DM-beta-CD-GNs modified glassy carbon electrode (DM-beta-CD-GNs/GCE), the peak currents of the two drugs increased dramatically compared with that on the bare GCE and GNs/GCE which due to the synergetic effects of GNs and DM-beta-CD molecules. Carbon 38-44 aminomethyltransferase Homo sapiens 71-74 28915042-0 2018 Mode of PEG Coverage on Carbon Nanotubes Affects Binding of Innate Immune Protein C1q. Carbon 24-30 complement C1q A chain Homo sapiens 82-85 35267723-9 2022 Hence, it is concluded that using carbon FRP bolted flange connection should be considered when increasing the joint stiffness is sought. Carbon 34-40 secreted frizzled related protein 1 Homo sapiens 41-44 28915042-2 2018 Here, we study the interaction of PEG-covered carbon nanotubes (CNTs) with the serum complement protein C1q. Carbon 46-52 complement C1q A chain Homo sapiens 104-107 35113524-6 2022 The optimized Li2.6Er0.6Zr0.4Cl6 electrolyte exhibits both a high ionic conductivity of 1.13 mS cm-1 and a high oxidation voltage of 4.21 V. Furthermore, carbon additives are demonstrated to be beneficial for achieving high discharge capacity and better cycling stability and rate performance for halide-based ASSLIBs, which are completely different from the case of sulfide electrolytes. Carbon 154-160 ATP binding cassette subfamily A member 12 Homo sapiens 14-17 29266921-2 2018 To overcome its poor ionic and electrical conductivities, LFP is often nanostructured, and its surface is coated with conductive carbon (LFP/C). Carbon 129-135 lamin A/C Homo sapiens 58-61 29266921-2 2018 To overcome its poor ionic and electrical conductivities, LFP is often nanostructured, and its surface is coated with conductive carbon (LFP/C). Carbon 129-135 lamin A/C Homo sapiens 137-140 24238940-2 2014 In the LiBC structure, boron and carbon are arranged to hetero graphite layers between which lithium is incorporated. Carbon 33-39 cellular communication network factor 6 Homo sapiens 7-11 35073524-3 2022 This paper reports a four-sensor array employing different nano-carbon sensitive layers (bare graphene, SnO2@Graphene, WO3@Graphene, and Au@CNTs). Carbon 64-70 strawberry notch homolog 1 Homo sapiens 104-107 25089242-3 2014 Compounds 1 and 2, two new decaoxygenated limonoids with a C-19/29 lactol bridge and heptaoxygenated substituents at C-1, C-2, C-3, C-7, C-11, C-17, and C-30, represent the second example of limonoids in the Euphorbiaceae family. Carbon 0-1 complement C2 Homo sapiens 122-130 25089242-3 2014 Compounds 1 and 2, two new decaoxygenated limonoids with a C-19/29 lactol bridge and heptaoxygenated substituents at C-1, C-2, C-3, C-7, C-11, C-17, and C-30, represent the second example of limonoids in the Euphorbiaceae family. Carbon 0-1 cytokine like 1 Homo sapiens 143-147 29266921-5 2018 This results in a LFP nanonetwork consisting of interconnected ~10 nm-sized particles covered by a uniform carbon coating that displays a high rate performance and an excellent cycle life. Carbon 107-113 lamin A/C Homo sapiens 18-21 29675243-3 2018 Herein we, for the first time, report vanadium-doped CoP on self-supported conductive carbon cloth (V-CoP/CC) as a robust HER electrocatalyst, which achieves ultra-low overpotentials of 71, 123 and 47 mV to afford a current density of 10 mA cm-2 in 1 M KOH, 1 M PBS and 0.5 M H2SO4 media, respectively. Carbon 86-92 caspase recruitment domain family member 16 Homo sapiens 53-56 29675243-3 2018 Herein we, for the first time, report vanadium-doped CoP on self-supported conductive carbon cloth (V-CoP/CC) as a robust HER electrocatalyst, which achieves ultra-low overpotentials of 71, 123 and 47 mV to afford a current density of 10 mA cm-2 in 1 M KOH, 1 M PBS and 0.5 M H2SO4 media, respectively. Carbon 86-92 caspase recruitment domain family member 16 Homo sapiens 102-105 35147879-9 2022 (4) We expect that by 2035, the districts facing carbon loss caused by the growth of urban built-up land will expand outward around secondary roads, and the scale of outward expansion under various scenarios will be ranked as BS > CP > EP. Carbon 49-55 epiregulin Homo sapiens 236-238 24789272-2 2014 Cytosolic serine hydroxymethyltransferase (cSHMT) is a critical enzyme in one-carbon metabolism pathway. Carbon 78-84 serine hydroxymethyltransferase 1 Homo sapiens 0-41 24789272-2 2014 Cytosolic serine hydroxymethyltransferase (cSHMT) is a critical enzyme in one-carbon metabolism pathway. Carbon 78-84 serine hydroxymethyltransferase 1 Homo sapiens 43-48 29090434-9 2018 This eventually ensures low carbon emissions and sustainable economic development across the G20 nations. Carbon 28-34 chromosome 3 open reading frame 18 Homo sapiens 93-96 24850432-1 2014 Micropore engineering of porous carbons on the effect of capacitance was explored using a carbonized porous aromatic framework (PAF-1). Carbon 32-39 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 128-133 35084174-6 2022 In comparison, TC-S, where sulfur is encapsulated within the open matrix formed by the nanofiber network of the carbon paper, displays poorer polysulfide confinement. Carbon 112-118 treacle ribosome biogenesis factor 1 Homo sapiens 15-19 24992664-0 2014 Multi-walled carbon nanotubes impair Kv4.2/4.3 channel activities, delay membrane repolarization and induce bradyarrhythmias in the rat. Carbon 13-19 potassium voltage-gated channel subfamily D member 2 Rattus norvegicus 37-46 29413358-2 2018 Eighteen and 20-carbon precursors to highly unsaturated n-3 and n-6 fatty acids are the usual substrates for FADS1 and FADS2. Carbon 16-22 fatty acid desaturase 1 Homo sapiens 109-114 35081352-5 2022 Mic10 variants impaired in MICOS functions stimulate ATP synthase oligomerization like wild-type Mic10 and promote efficient inner membrane energization, adaptation to non-fermentable carbon sources, and respiratory growth. Carbon 184-190 mitochondrial contact site and cristae organizing system subunit 10 Homo sapiens 0-5 29599911-3 2018 Carbon ion beam (at the center of SOBP with 50 keV/microm of average LET) dose-independently suppressed MM cells MESO-1 and H226 cell viability and in combination with CDDP (25 muM) significantly enhanced its action. Carbon 0-6 sine oculis binding protein homolog Homo sapiens 34-38 29276384-0 2017 Investigation of the effects of carbon-based nanomaterials on A53T alpha-synuclein aggregation using a whole-cell recombinant biosensor. Carbon 32-38 synuclein alpha Homo sapiens 67-82 24374032-6 2014 Clusters promote the reconfiguration of the thin filament to the "On" state; this simultaneously increases thin filaments" affinity for myosin heads and of troponin C for Ca(2+) producing the highly cooperative pCa/force curve. Carbon 0-1 myosin heavy chain 14 Homo sapiens 136-142 34989879-2 2022 In this study, we introduced a novel Ti3C2Tx (MXene) aerogels (denoted as MXA) composite gold nano-particles (AuNPs)-modified disposable carbon fiber paper (CFP) electrode for the label-free and sensitive detection of miRNA-155. Carbon 137-143 MX dynamin like GTPase 1 Homo sapiens 74-77 24770487-1 2014 LDL-cholesterol (LDL-C) uptake by Ldlr is regulated at the transcriptional level by the cleavage-dependent activation of membrane-associated sterol response element-binding protein (SREBP-2). Carbon 21-22 low density lipoprotein receptor Homo sapiens 34-38 24760149-7 2014 The roles of NF-kappaB and IFN regulatory factor-3 (IRF-3) in the poly(I:C)-mediated production of MMPs and the responsiveness to poly(I:C) of normal lung fibroblasts and asthmatic lung fibroblasts were also investigated. Carbon 73-74 matrix metallopeptidase 1 Homo sapiens 99-103 29594398-0 2017 Impedimetric PSA aptasensor based on the use of a glassy carbon electrode modified with titanium oxide nanoparticles and silk fibroin nanofibers. Carbon 57-63 kallikrein related peptidase 3 Homo sapiens 13-16 34974624-0 2022 UCP1 and AOX1a contribute to regulation of carbon and nitrogen metabolism and yield in Arabidopsis under low nitrogen stress. Carbon 43-49 alternative oxidase 1A Arabidopsis thaliana 9-14 29416662-7 2018 In contrast to XN, isoXN showed much less effects on the kinase activity of IKKbeta and IkappaBalpha phosphorylation induced by XN in this study, suggesting that an electrophilic carbon center present in XN is critical for the anti-inflammation in colitis, especially inhibition of IKKbeta/NF-kappaB signaling pathway. Carbon 179-185 inhibitor of kappaB kinase beta Mus musculus 282-289 24727688-4 2014 Here, we show that, in addition to conventional nanoparticle-uptake mechanisms, single-walled carbon nanotubes are almost exclusively taken up by a single immune cell subset, Ly-6C(hi) monocytes (almost 100% uptake in Ly-6C(hi) monocytes, below 3% in all other circulating cells), and delivered to the tumour in mice. Carbon 94-100 lymphocyte antigen 6 complex, locus C1 Mus musculus 175-180 24727688-4 2014 Here, we show that, in addition to conventional nanoparticle-uptake mechanisms, single-walled carbon nanotubes are almost exclusively taken up by a single immune cell subset, Ly-6C(hi) monocytes (almost 100% uptake in Ly-6C(hi) monocytes, below 3% in all other circulating cells), and delivered to the tumour in mice. Carbon 94-100 lymphocyte antigen 6 complex, locus C1 Mus musculus 218-223 29032197-11 2017 In mouse lung cells in vivo, IL-22 suppressed poly I:C-induced upregulation of PD-L1. Carbon 53-54 interleukin 22 Mus musculus 29-34 16667188-0 1989 Mechanism of c(4) photosynthesis: a model describing the inorganic carbon pool in bundle sheath cells. Carbon 67-73 complement C4A (Rodgers blood group) Homo sapiens 13-17 29182171-2 2017 Here, we report a unique 2D Mg2C monolayer featuring quasi-planar hexa-coordinate magnesium and hexa-coordinate carbon, which can be tuned from a metal to a semiconductor. Carbon 112-118 hexosaminidase subunit alpha Homo sapiens 96-100 28778973-0 2017 Impact of folic acid intake during pregnancy on genomic imprinting of IGF2/H19 and 1-carbon metabolism. Carbon 85-91 H19 imprinted maternally expressed transcript Homo sapiens 75-84 28778973-10 2017 Impact of folic acid intake during pregnancy on genomic imprinting of IGF2/H19 and 1-carbon metabolism. Carbon 85-91 H19 imprinted maternally expressed transcript Homo sapiens 75-84 28497245-2 2017 Inorganic carbon takes the forms of "CO2" (dissolved CO2 and carbonic acid) and "CARB" (bicarbonate and carbonate ions), which are substitutable in their effects on algal growth. Carbon 10-16 complement C2 Homo sapiens 36-40 29285428-6 2017 Among patients with ESRD, hs-TnT showed significant correlations with the low-density lipoprotein cholesterol/high-density lipoprotein cholesterol (HDL-C) (P = 0.042, r = 0.278) and total cholesterol/HDL-C (P = 0.044, r = 0.276) ratios. Carbon 151-153 troponin T1, slow skeletal type Homo sapiens 29-32 28565884-1 2017 LiNi0.8Co0.15Al0.05O2/carbon nanotube (NCA/CNT) composite cathode materials are prepared by a facile mechanical grinding method, without damage to the crystal structure and morphology of the bulk. Carbon 22-28 CEA cell adhesion molecule 6 Homo sapiens 39-42 29249848-5 2017 Analysis of the crystal structures suggests that their formation is influenced by steric interactions between the p-cym and AZBTZ-NMe2 ligands: in particular, larger monodentate halide ligands favor N,C-coordination. Carbon 201-202 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 130-134 28965784-2 2017 The Saccharomyces cerevisiae lactate transporter Jen1p has been used as a model cargo for elucidating the mechanisms underlying endocytic turnover in response to carbon sources. Carbon 162-168 Jen1p Saccharomyces cerevisiae S288C 49-54 28924051-3 2017 We also found that transcript levels of MSN2/MSN4 are increased in glucose-depletion conditions and that during growth in nonpreferred carbon sources, Msn2 is constantly localized to the nucleus in wild-type cells. Carbon 135-141 stress-responsive transcriptional activator MSN2 Saccharomyces cerevisiae S288C 40-44 28924051-3 2017 We also found that transcript levels of MSN2/MSN4 are increased in glucose-depletion conditions and that during growth in nonpreferred carbon sources, Msn2 is constantly localized to the nucleus in wild-type cells. Carbon 135-141 stress-responsive transcriptional activator MSN2 Saccharomyces cerevisiae S288C 151-155 29035505-5 2017 To our knowledge, {(PW9)2Ni7}/{Cu(ethylenediamine)2}/TTF-F represents the first example of POM-based noble-metal-free ORR electrocatalyst possessing both comparable ORR electrocatalytic activity and much higher stability than that of Pt/C in neutral medium. Carbon 31-32 ras homolog family member H Homo sapiens 53-58 29079776-6 2017 We identify the kinase GCN2 as a sensor of the carbon/nitrogen precursor availability, whereas limitation of the sulfur precursor is transduced to TOR by downregulation of glucose metabolism. Carbon 47-53 protein kinase family protein Arabidopsis thaliana 23-27 29079776-9 2017 In concert with GCN2, TOR allows photo-autotrophic eukaryotes to coordinate the fluxes of carbon, nitrogen, and sulfur for efficient cysteine biosynthesis under varying external nutrient supply. Carbon 90-96 protein kinase family protein Arabidopsis thaliana 16-20 29063832-2 2017 We show that daf-16/FoxO restructures carbohydrate metabolism by driving carbon flux through the glyoxylate shunt and gluconeogenesis and into synthesis of trehalose, a disaccharide of glucose. Carbon 73-79 Fork-head domain-containing protein;Forkhead box protein O Caenorhabditis elegans 13-19 29063832-6 2017 This work demonstrates that daf-16/FoxO promotes starvation resistance by shifting carbon metabolism to drive trehalose synthesis, which in turn supports survival by providing an energy source and acting as a stress protectant. Carbon 83-89 Fork-head domain-containing protein;Forkhead box protein O Caenorhabditis elegans 28-34 29073064-1 2017 The enzyme serine hydroxymethyltransferse (SHMT) converts serine into glycine and a tetrahydrofolate-bound one-carbon unit. Carbon 111-117 serine hydroxymethyltransferase 1 Homo sapiens 11-41 29073064-1 2017 The enzyme serine hydroxymethyltransferse (SHMT) converts serine into glycine and a tetrahydrofolate-bound one-carbon unit. Carbon 111-117 serine hydroxymethyltransferase 1 Homo sapiens 43-47 29073064-8 2017 The one-carbon donor formate generally rescues cells from SHMT inhibition, but paradoxically increases the inhibitor"s cytotoxicity in diffuse large B-cell lymphoma (DLBCL). Carbon 8-14 serine hydroxymethyltransferase 1 Homo sapiens 58-62 28956436-6 2017 The reported porous carbons also show significantly high adsorption selectivity for CO2/N2 (128) and CO2/CH4 (13.4) according to ideal adsorbed solution theory calculations at 298 K. Gas breakthrough studies of CO2/N2 (10:90) at 298 K showed that PYDCs display excellent separation properties. Carbon 20-27 complement C2 Homo sapiens 84-90 28847921-9 2017 Compared to the intact enzyme, the FAD-containing dehydrogenase domain showed increased catalytic efficiency with cytochrome c as the electron acceptor, but it completely lost the ability to use coenzyme Q10 Additionally, the FAD-containing dehydrogenase domain was no longer associated with the cell membrane, and it could not support the utilization of d-lactate as a carbon source. Carbon 370-376 cytochrome c Pseudomonas putida KT2440 114-126 28550749-1 2017 A non enzymatic modified electrode was constructed based on the modification of carbon paste electrode with CuO nanoflower (CuO-CPE). Carbon 80-86 carboxypeptidase E Homo sapiens 128-131 28884569-2 2017 Herein, we developed a drug delivery platform of carbon dots which were connected to a stem-loop molecular beacon loaded with doxorubicin and polyethylene glycol modified folic acid. Carbon 49-55 ubiquitin like 5 Homo sapiens 107-113 28715134-1 2017 The carbon-carbon bonds in the ground states of C2 and C2 H2 , at their equilibrium geometries, are compared by analysing the changes in the off-nucleus magnetic shielding tensor within the space surrounding each of these molecules. Carbon 4-10 complement C2 Homo sapiens 48-60 28715134-1 2017 The carbon-carbon bonds in the ground states of C2 and C2 H2 , at their equilibrium geometries, are compared by analysing the changes in the off-nucleus magnetic shielding tensor within the space surrounding each of these molecules. Carbon 11-17 complement C2 Homo sapiens 48-60 28715134-5 2017 According to the results of the shielding calculations, the carbon nuclei in C2 should be much more shielded than those in C2 H2 , with 13 C isotropic magnetic shieldings in the ranges of around 224-227 ppm and around 123-125 ppm for C2 and C2 H2 , respectively. Carbon 60-66 complement C2 Homo sapiens 234-246 30965700-1 2017 In this paper, the dispersion of carbon nanotube (CNT) in ethylene vinyl acetate (EVA) is demonstrated to be significantly improved by the addition of octadecylamine (ODA)-grafted graphene oxide (GO) (GO-ODA). Carbon 33-39 myelin protein zero like 2 Homo sapiens 82-85 28700826-4 2017 Compared with other published carbon materials modified sensors, the annealed coal/chitosan/GCE sensor exhibited excellent electrocatalytic activity for the determination of rutin with good sensitivity, providing a wide linear detection range from 0.001 to 10 mumol dm-3 and a low detection limit of 0.2 nmol dm-3 (S/N = 3). Carbon 30-36 aminomethyltransferase Homo sapiens 92-95 28619629-1 2017 The impact of seasonal coastal upwelling on the dynamics of dissolved inorganic carbon (DIC) and sea-air fluxes of CO2 along the coastal waters of Kochi was investigated during 2015, as a part of Ecosystem Modelling Project. Carbon 80-86 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 14-17 28673683-0 2017 Single-walled carbon nanotubes (SWCNTs) inhibit heat shock protein 90 (HSP90) signaling in human lung fibroblasts and keratinocytes. Carbon 14-20 heat shock protein 90 alpha family class A member 1 Homo sapiens 48-69 28673683-0 2017 Single-walled carbon nanotubes (SWCNTs) inhibit heat shock protein 90 (HSP90) signaling in human lung fibroblasts and keratinocytes. Carbon 14-20 heat shock protein 90 alpha family class A member 1 Homo sapiens 71-76 28673683-12 2017 Finally, we showed that ectopic expression of HSP90, but not HSP40 or HSP70, completely abrogated the cytotoxic effects of SWCNTs, suggesting that SWCNT-induced cellular toxicity is HSP90 dependent. Carbon 123-128 heat shock protein 90 alpha family class A member 1 Homo sapiens 46-51 28673683-12 2017 Finally, we showed that ectopic expression of HSP90, but not HSP40 or HSP70, completely abrogated the cytotoxic effects of SWCNTs, suggesting that SWCNT-induced cellular toxicity is HSP90 dependent. Carbon 123-128 heat shock protein 90 alpha family class A member 1 Homo sapiens 182-187 28737377-0 2017 Carbon Dot Based, Naphthalimide Coupled FRET Pair for Highly Selective Ratiometric Detection of Thioredoxin Reductase and Cancer Screening. Carbon 0-6 peroxiredoxin 5 Homo sapiens 96-117 28631465-2 2017 A fully printable perovskite (CH3NH3PbI3) solar cell (PSC) with device architecture FTO/TiO2/Al2O3/NiOx/C is fabricated in the current research as a low-cost and relatively stable structure and is investigated to determine how different fabrication factors such as the thickness of the insulating spacer layer (Al2O3) or treatments such as heat and UV-O3 treatments can affect the interfacial properties of this multilayer mesoporous structure. Carbon 30-31 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 84-87 28455099-2 2017 The C-terminal hypervariable region (HVR) of Rab5 is post-translationally modified at residues Cys212 and Cys213 to accommodate two geranylgeranyl anchors (C20 carbon chain length) in order to associate Rab5 with the membrane. Carbon 160-166 RAB5A, member RAS oncogene family Homo sapiens 45-49 28476000-1 2017 In this study, iodine-doped granular activated carbon (I-GAC) was prepared and subsequently applied to activate periodate (IO4-) to degrade organic contaminants at ambient temperature. Carbon 47-53 glutaminase Homo sapiens 57-60 28854669-1 2017 A yeast Saccharomyces cerevisiae Snf1 kinase, an analog of mammalian AMPK, regulates glucose derepression of genes required for utilization of alternative carbon sources through the transcriptional repressor Mig1. Carbon 155-161 vacuolar protein sorting 4 homolog B Homo sapiens 208-212 28317708-2 2017 The nanoparticles of ruthenium (RuNPs) were obtained at carbon nanotubes modified GCE by cyclic voltammetry. Carbon 56-62 aminomethyltransferase Homo sapiens 82-85 28120533-2 2017 We have recently demonstrated that nanovectorization of TRAIL with single-walled carbon nanotubes enhanced TRAIL affinity to DR5. Carbon 81-87 TNF receptor superfamily member 10b Homo sapiens 125-128 28993718-4 2017 The procedure for estimating the pKa of uridine 5"-phosphate for C-6 deprotonation at the active site of orotidine 5"-phosphate decarboxylase is described, and the effect of a 5-F substituent on carbon acidity of the enzyme-bound substrate is discussed. Carbon 195-201 uridine monophosphate synthetase Homo sapiens 105-141 28623948-17 2017 This is partially explained by associations with CSF tau and p-tau181, suggesting a role for one-carbon metabolism in the aggregation of tau and neuronal injury. Carbon 97-103 microtubule associated protein tau Homo sapiens 53-56 28623948-17 2017 This is partially explained by associations with CSF tau and p-tau181, suggesting a role for one-carbon metabolism in the aggregation of tau and neuronal injury. Carbon 97-103 microtubule associated protein tau Homo sapiens 63-66 28593983-0 2017 The G20 must govern the shift to low-carbon energy. Carbon 37-43 chromosome 3 open reading frame 18 Homo sapiens 4-7 27687857-2 2017 Compound 1 has a alpha,beta-unsaturated-gamma-lactone ring conjugated with the C-22/23 olefin in the C-17 side chain. Carbon 0-1 cytokine like 1 Homo sapiens 101-105 28334829-5 2017 Although deleting Sac3 residues 1-90 produced a wild-type phenotype, deletion of the loop as well generated growth defects at 37 C, whereas the deletion of residues 1-250 impaired mRNA export and also generated longer lag times when glucose or raffinose was replaced by galactose as the carbon source. Carbon 287-293 Sac3p Saccharomyces cerevisiae S288C 18-22 29297557-11 2017 SYS had the lowest and PT4 the highest degree of C=C conversion after 10 min. Carbon 49-50 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 0-3 29297557-11 2017 SYS had the lowest and PT4 the highest degree of C=C conversion after 10 min. Carbon 51-52 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 0-3 28446542-2 2017 Chalcone synthase (CHS) catalyzes the first step of flavonoid biosynthesis by directing carbon flux from general phenylpropanoid metabolism to flavonoid pathway. Carbon 88-94 Chalcone and stilbene synthase family protein Arabidopsis thaliana 0-17 28379232-3 2017 The regioselectivity for different C-H activation sites depends on the coordination structures of alpha-C or beta-C to the palladium(ii) center. Carbon 35-36 colony stimulating factor 2 receptor subunit beta Homo sapiens 109-115 28339198-1 2017 We previously reported the design of spirooxindoles with two identical substituents at the carbon-2 of the pyrrolidine core as potent MDM2 inhibitors. Carbon 91-97 transformed mouse 3T3 cell double minute 2 Mus musculus 134-138 27909749-6 2017 Analysis of the cbbM gene showed that Alphaproteobacterial members such as the purple non-sulfur bacteria were the major chemoautotrophic bacteria involving in carbon fixation via the Calvin-Benson-Bassham (CBB) cycle. Carbon 160-166 opsin 1, medium wave sensitive Homo sapiens 16-20 28189064-0 2017 Oral application of carbon nanofibers in rats increases blood concentration of IL6 and IL10 and decreases locomotor activity. Carbon 20-26 interleukin 10 Rattus norvegicus 87-91 27880021-9 2017 These data support the idea that modulation of NDPK1 affects the distribution of carbon between starch and cellulose biosynthetic pathways. Carbon 81-87 nucleoside diphosphate kinase Solanum tuberosum 47-52 28292465-8 2017 RESULTS: LPS and poly(I:C) significantly decreased phosphorylation of IR-beta, IRS-1, Akt, total PI3K-p85alpha protein expression and glucose uptake. Carbon 24-25 insulin receptor substrate 1 Homo sapiens 79-84 28177243-1 2017 The absolute configuration at C-17, the carbon bearing the distal hydroxy group of the 14-membered natural product gliomasolide D, was assigned as R by comparison of 13C NMR shifts and specific rotation values of the epimers at C-17. Carbon 40-46 cytokine like 1 Homo sapiens 30-34 28177243-1 2017 The absolute configuration at C-17, the carbon bearing the distal hydroxy group of the 14-membered natural product gliomasolide D, was assigned as R by comparison of 13C NMR shifts and specific rotation values of the epimers at C-17. Carbon 40-46 cytokine like 1 Homo sapiens 228-232 27878872-1 2017 Carbon electrocatalysts consisting of metal complexes such as MNx or MSx are promising alternatives to high-cost Pt catalysts for the hydrogen evolution reaction (HER). Carbon 0-6 keratin 86 Homo sapiens 62-65 27340756-5 2017 The highest beta-glucosidase activity was produced on 4% wheat bran (WB) as raw carbon sources, reaching 5 U/mL. Carbon 80-86 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1a, chloroplastic Triticum aestivum 12-28 28152100-5 2017 To investigate whether starch breakdown products can be recycled back to starch during illumination through a mechanism involving ADP-glucose pyrophosphorylase (AGP) we conducted kinetic analyses of the stable isotope carbon composition (delta13C) in starch of leaves of 13CO2 pulsed-chased WT and AGP lacking aps1 plants. Carbon 218-224 ADP-glucose pyrophosphorylase small subunit 2 Arabidopsis thaliana 130-159 28152100-5 2017 To investigate whether starch breakdown products can be recycled back to starch during illumination through a mechanism involving ADP-glucose pyrophosphorylase (AGP) we conducted kinetic analyses of the stable isotope carbon composition (delta13C) in starch of leaves of 13CO2 pulsed-chased WT and AGP lacking aps1 plants. Carbon 218-224 ADP-glucose pyrophosphorylase small subunit 2 Arabidopsis thaliana 161-164 27987663-1 2017 An electrochemical sensor for determining dopamine was developed by modifying phytic acid/graphene oxide (PA/GO) nanocomposites onto a glassy carbon electrode (GCE). Carbon 142-148 aminomethyltransferase Homo sapiens 160-163 28243563-5 2017 In this context, nanotechnology has offered a significant number of proposed solutions, mainly based on the functionalization of nanoparticles from gold to carbon which could be used as antibody carriers as well as reporter enzymes like peroxidase. Carbon 156-162 peroxidase-like Triticum aestivum 237-247 27897388-4 2017 Unexpectedly, calcium complexes ((L3-5 )CaN(SiMe3 )2 ) bearing more sterically encumbered ligands of the same type were extremely unstable and underwent C-N bond cleavage processes as a consequence of intramolecular C-H bond activation, leading to the exclusive formation of (E)-1,2-bis(8-isopropylquinol-2-yl)ethane. Carbon 40-41 ribosomal protein L35 Homo sapiens 34-38 28027722-4 2017 Celastrol significantly inhibited poly(I:C)-induced expression of adhesion molecules, such as ICAM-1/VCAM-1, and chemokines, such as CCL2, CXCL8, and CXCL10, in CRT-MG human astroglioma cells. Carbon 0-1 C-C motif chemokine ligand 2 Homo sapiens 133-137 27662023-0 2017 Development of electrochemical sensor for the determination of palladium ions (Pd2+) using flexible screen printed un-modified carbon electrode. Carbon 127-133 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 79-82 27662023-3 2017 Hence, we report an electrochemical sensor for the determination of palladium ions (Pd2+) using an un-modified screen printed carbon electrode has been developed for the first time, which are characterized and studied via scanning electron microscope and cyclic voltammetry. Carbon 126-132 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 84-87 28062703-0 2017 TAS-116, a Novel Hsp90 Inhibitor, Selectively Enhances Radiosensitivity of Human Cancer Cells to X-rays and Carbon Ion Radiation. Carbon 108-114 heat shock protein 90 alpha family class A member 1 Homo sapiens 17-22 30460315-1 2017 Abstract: By means of inkjet printing technique, flexible and all-solid-state micro-supercapacitors (MSCs) were fabricated with carbon-based hybrid ink composed of graphene oxide (GO, 98.0 vol.%) ink and commercial pen ink (2.0 vol.%). Carbon 128-134 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 215-218 27983623-8 2016 The thiamine-dependent regulation of GDH is in good agreement with the fact that the non-coenzyme forms of thiamine, i.e., thiamine triphosphate and its adenylated form are generated in response to amino acid and carbon starvation. Carbon 213-219 glutamate dehydrogenase 1 Homo sapiens 37-40 27924923-1 2016 Phosphoenolpyruvate carboxylase (PEPC) plays an important role in assimilating atmospheric CO2 during C4 and crassulacean acid metabolism photosynthesis, and also participates in various non-photosynthetic processes, including fruit ripening, stomatal opening, supporting carbon-nitrogen interactions, seed formation and germination, and regulation of plant tolerance to stresses. Carbon 272-278 phosphoenolpyruvate carboxylase, housekeeping isozyme Glycine max 0-31 27924923-1 2016 Phosphoenolpyruvate carboxylase (PEPC) plays an important role in assimilating atmospheric CO2 during C4 and crassulacean acid metabolism photosynthesis, and also participates in various non-photosynthetic processes, including fruit ripening, stomatal opening, supporting carbon-nitrogen interactions, seed formation and germination, and regulation of plant tolerance to stresses. Carbon 272-278 phosphoenolpyruvate carboxylase, housekeeping isozyme Glycine max 33-37 27808302-3 2016 POx-C was immobilized on a special screen-printed electrode (SPE) based on carbon ink and grafted with gold-nanoparticles (GNP). Carbon 75-81 proline dehydrogenase 1 Homo sapiens 0-3 27798961-2 2016 Ground state carbon atoms are generated by 248 nm laser photolysis of tetrabromomethane, CBr4, in a buffer of helium. Carbon 13-19 carbonyl reductase 4 Homo sapiens 89-93 27750195-2 2016 Our working group has recently demonstrated that nanovectorization of TRAIL with single wall carbon nanotubes (abbreviated NPT) enhanced TRAIL affinity to the high affinity site DR5 and increased pro apoptotic potential in different human tumor cell lines. Carbon 93-99 TNF receptor superfamily member 10b Homo sapiens 178-181 27665314-6 2016 Furthermore, pharmacological modulation of [Ca2+]c with 1,2-Bis (2-aminophenoxy) ethane-N,N,N",N"-tetraacetic acid acetoxymethyl ester (BAPTA-AM) and 2-APB alleviated Cd-mediated apoptosis, inhibition of autophagic degradation and subsequent cytotoxicity, while thapsigargin (TG) had the opposite regulatory effect on them. Carbon 19-20 arginyl aminopeptidase Rattus norvegicus 152-155 27711538-4 2016 The Glu451-assisted water addition on amide carbon atoms and nitrogen inversion (i.e. change of pyramidalization on the leaving nitrogen) are shown to be the rate-determining steps with the activation energies in a good agreement with the experimental results for the Leu-enkephalin hydrolysis. Carbon 44-50 prodynorphin Homo sapiens 268-282 27841564-2 2016 However, it is in many cases not straightforward to analyze what is the actual defect structure underlying the RBS/C signal. Carbon 115-116 establishment of sister chromatid cohesion N-acetyltransferase 2 Homo sapiens 111-114 26381241-2 2016 To investigate the intermolecular interaction and binding affinity between the EGF-conjugated DDS and the EGFR, 50 ns molecular dynamics simulations were performed on the complex of tethered EGFR and EGF linked to single-wall carbon nanotube (SWCNT) through a biopolymer chitosan wrapping the tube outer surface (EGFR EGF-CS-SWCNT-Drug complex), and compared to the EGFR EGF complex and free EGFR. Carbon 226-232 epidermal growth factor Homo sapiens 79-82 26381241-2 2016 To investigate the intermolecular interaction and binding affinity between the EGF-conjugated DDS and the EGFR, 50 ns molecular dynamics simulations were performed on the complex of tethered EGFR and EGF linked to single-wall carbon nanotube (SWCNT) through a biopolymer chitosan wrapping the tube outer surface (EGFR EGF-CS-SWCNT-Drug complex), and compared to the EGFR EGF complex and free EGFR. Carbon 226-232 epidermal growth factor Homo sapiens 106-109 26381241-2 2016 To investigate the intermolecular interaction and binding affinity between the EGF-conjugated DDS and the EGFR, 50 ns molecular dynamics simulations were performed on the complex of tethered EGFR and EGF linked to single-wall carbon nanotube (SWCNT) through a biopolymer chitosan wrapping the tube outer surface (EGFR EGF-CS-SWCNT-Drug complex), and compared to the EGFR EGF complex and free EGFR. Carbon 226-232 epidermal growth factor Homo sapiens 106-109 27510174-6 2016 More importantly, short type MWCNT at low concentration of 50 ng/ml stimulated microtissue formation and contraction force generation, and caused substantial increase in the fibrogenic marker miR-21 expression, indicating the high fibrogenic potential of this specific carbon nanotube type and concentration. Carbon 269-275 microRNA 21 Homo sapiens 192-198 27343244-4 2016 We now report that depriving cells of serine and glycine promotes RR formation, and we have traced these effects to dihydrofolate reductase (DHFR) and serine hydroxymethyltransferase-2 (SHMT2), pivotal enzymes in one-carbon metabolism and nucleotide biosynthesis. Carbon 217-223 dihydrofolate reductase Homo sapiens 116-139 27343244-4 2016 We now report that depriving cells of serine and glycine promotes RR formation, and we have traced these effects to dihydrofolate reductase (DHFR) and serine hydroxymethyltransferase-2 (SHMT2), pivotal enzymes in one-carbon metabolism and nucleotide biosynthesis. Carbon 217-223 dihydrofolate reductase Homo sapiens 141-145 27436713-8 2016 (14)C labeling showed that amy3 bam1 plants have reduced carbon export to the root, affecting osmolyte accumulation and root growth during stress. Carbon 57-63 amylase alpha 2B Homo sapiens 27-31 32908390-6 2016 Poly I:C down-regulated the expression of CATH1, -2 and -3, whereas R848 up-regulated the expression of CATH1 and CATH3 but down-regulated the expression of CATH2. Carbon 7-8 cath1, -2 and -3 None 42-58 27348072-0 2016 Tip-Enhanced Raman Spectroscopic Imaging of Individual Carbon Nanotubes with Subnanometer Resolution. Carbon 55-61 TOR signaling pathway regulator Homo sapiens 0-3 27362224-9 2016 We demonstrate carbon synthesis for large-pore zeolites (FAU, EMT and beta), a one-dimensional medium-pore zeolite (LTL), and even small-pore zeolites (MFI and LTA). Carbon 15-21 IL2 inducible T cell kinase Homo sapiens 62-74 27166981-4 2016 A series of pressure-induced structural transformations are predicted, I4/mmm (i.e. experimental alpha phase) C2/c Pnma Pmma, which involve the catenation of carbon from a dimer to zigzag C4 units and further to armchair polymer chains. Carbon 159-165 complement C2 Homo sapiens 111-125 27133130-6 2016 These findings describe a competitive and partially redundant relationship between transaminases and GLUD, and they reveal how coupling of glutamate-derived carbon and nitrogen metabolism can be regulated to support cell proliferation. Carbon 157-163 glutamate dehydrogenase 1 Homo sapiens 101-105 27065057-10 2016 The heterogeneous electron transfer rate between the Ru complex, Ru-2, and the carbon nanomaterials increased in the order SWCNTs (kET = 1.3 s(-1)) < MWCNTs (phi = 5-9 nm) (kET = 4.0 s(-1)) < MWCNTs (phi = 110-170 nm) (kET = 14.9 s(-1)) < HOPG (kET = 110 s(-1)). Carbon 79-85 doublecortin domain containing 2 Homo sapiens 65-69 27417724-0 2016 Electroanalysis of myoglobin based on electropolymerized molecularly imprinted polymer poly-o-phenylenediamine and carbon nanotubes/screen printed electrode. Carbon 115-121 myoglobin Homo sapiens 19-28 27417724-1 2016 Electroanalysis of myoglobin as a marker of acute myocardial infarction by means of screenprinted electrodes modified with multiwalled carbon nanotubes and polymeric artificial antibodies is developed. Carbon 135-141 myoglobin Homo sapiens 19-28 26952453-1 2016 Poly-Alizarin red S/multiwalled carbon nanotube film on the surface of glassy carbon electrode (poly-AzrS/MWCNT/GCE) was synthesized by electrochemical process and was used for the sensitive and selective determination of dopamine (DA) by employing voltammetric techniques. Carbon 32-38 aminomethyltransferase Homo sapiens 112-115 26952453-1 2016 Poly-Alizarin red S/multiwalled carbon nanotube film on the surface of glassy carbon electrode (poly-AzrS/MWCNT/GCE) was synthesized by electrochemical process and was used for the sensitive and selective determination of dopamine (DA) by employing voltammetric techniques. Carbon 78-84 aminomethyltransferase Homo sapiens 112-115 27128465-3 2016 The carbon work, in turn, opened new vistas, including the discovery that thioredoxin functions universally in regulating the Calvin-Benson cycle in oxygenic photosynthesis. Carbon 4-10 thioredoxin Homo sapiens 74-85 26774957-0 2016 Multi-walled carbon nanotubes (NM401) induce ROS-mediated HPRT mutations in Chinese hamster lung fibroblasts. Carbon 13-19 hypoxanthine-guanine phosphoribosyltransferase Cricetulus griseus 58-62 26774957-2 2016 We have determined the ability of multi-walled carbon nanotubes (MWCNT, NM401), to induce mutations in the HPRT gene in Chinese hamster lung (V79) fibroblasts. Carbon 47-53 hypoxanthine-guanine phosphoribosyltransferase Cricetulus griseus 107-111 26991128-0 2016 Arabidopsis lipoxygenase 2 is essential for formation of green leaf volatiles and five-carbon volatiles. Carbon 87-93 lipoxygenase 2 Arabidopsis thaliana 12-26 26991128-3 2016 We found that formation of five carbon volatiles was also dependent on LOX2. Carbon 32-38 lipoxygenase 2 Arabidopsis thaliana 71-75 32263183-1 2016 We describe a straightforward tactic to boost the inherently low peroxidase-like activity of the heme-protein equine cytochrome c (cyt c) following its electrostatic assembly onto the carbon nanodot surface. Carbon 184-190 cytochrome c, somatic Equus caballus 117-129 32263183-1 2016 We describe a straightforward tactic to boost the inherently low peroxidase-like activity of the heme-protein equine cytochrome c (cyt c) following its electrostatic assembly onto the carbon nanodot surface. Carbon 184-190 cytochrome c, somatic Equus caballus 131-136 32263183-3 2016 The dramatic enhancement in peroxidase-like activity stems in part from favorable local perturbations within the heme microenvironment of cyt c which are influenced by the chemistry presented at the carbon dot surface. Carbon 199-205 cytochrome c, somatic Equus caballus 138-143 32263183-5 2016 An exceptional catalytic efficiency (kcat/KM) of 8.04 (+-1.74) x 107 M-1 s-1 was determined for carbon dot/cyt c co-assemblies, close to the theoretical diffusion-controlled limit. Carbon 96-102 cytochrome c, somatic Equus caballus 107-112 32263183-6 2016 Notably, the activity of the carbon dot/cyt c assembly can be switched off simply by increasing the ionic strength which results in dissociation into non-catalytic components. Carbon 29-35 cytochrome c, somatic Equus caballus 40-45 26875934-5 2016 The prodrugs were also remarkably stable in mouse, rat, and human serum (relative serum stability: human~rat>>mouse) displaying a parabolic trend in the SAR with hydrolysis rates increasing with chain length up to eight carbons (t1/2=1.6 h for octanoyl prodrug 7 in mouse serum) and then decreasing again with higher chain lengths. Carbon 226-233 sarcosinemia autosomal recessive Mus musculus 159-162 26811938-2 2016 Herein, we report that nanoarrays of CoP supported on carbon cloth are an efficient bifunctional catalyst for overall water splitting. Carbon 54-60 caspase recruitment domain family member 16 Homo sapiens 37-40 26724864-6 2016 Because sedoheptulose-7-phosphate (S7P), a substrate of transaldolase, reduced significantly in the pho13Delta mutant as well, we hypothesized that limited transaldolase activity in the parental strain might cause dephosphorylation of S7P, leading to carbon loss and inefficient xylose metabolism. Carbon 251-257 4-nitrophenylphosphatase Saccharomyces cerevisiae S288C 100-110 26704642-0 2016 PSR1 Is a Global Transcriptional Regulator of Phosphorus Deficiency Responses and Carbon Storage Metabolism in Chlamydomonas reinhardtii. Carbon 82-88 uncharacterized protein Chlamydomonas reinhardtii 0-4 26875940-1 2016 Carbon-atom extrusion from the ipso-position of a halobenzene ring (C6 H5 X; X=F, Cl, Br, I) and its coupling with a methylene ligand to produce acetylene is not confined to [LaCH2 ](+) ; also, the third-row transition-metal complexes [MCH2 ](+) , M=Hf, Ta, W, Re, and Os, bring about this unusual transformation. Carbon 0-6 melanin concentrating hormone receptor 2 Homo sapiens 236-240 26661919-2 2016 The reaction proceeds under RuH2(CO)(PPh3)3-catalyzed conditions driven by unreactive C-O bond activation of a proximate ester directing group (DG)-catalyst chelation. Carbon 33-34 protein phosphatase 4 catalytic subunit Homo sapiens 37-41 26821604-2 2016 Multilayer graphene with relative rotations between carbon layers, known as turbostratic graphene, can effectively decouple the electronic states of adjacent layers, preserving properties similar to that of SLG. Carbon 52-58 sialic acid binding Ig like lectin 12 Homo sapiens 207-210 26332383-1 2016 A novel multiplexed ratiometric biosensor array was fabricated on a homemade screen-printed carbon electrode (SPCE) for near-simultaneous detection of microRNA (miRNA)-21 and miRNA-141 based on electrochemiluminescence (ECL) coupled with cyclic voltammetry (CV) method. Carbon 92-98 microRNA 21 Homo sapiens 151-170 26670775-2 2016 In the binary mixture, the biodegradation of less-degradable oxytetracycline (OTC) was restarted in the presence of more degradable benzo[a]pyrene (BaP) in the initial runs of the AMCBR, but enhanced biodegradation of the more recalcitrant OTC occurs in the later runs of the AMCBR due to enhanced biomass growth on dual substrates without the primary carbon source. Carbon 352-358 prohibitin 2 Homo sapiens 148-151 26241176-0 2016 Adenovirus-mediated FIR demonstrated TP53-independent cell-killing effect and enhanced antitumor activity of carbon-ion beams. Carbon 109-115 poly(U) binding splicing factor 60 Homo sapiens 20-23 26241176-1 2016 Combination therapy of carbon-ion beam with the far upstream element-binding protein (FBP)-interacting repressor, FIR, which interferes with DNA damage repair proteins, was proposed as an approach for esophageal cancer treatment with low side effects regardless of TP53 status. Carbon 23-29 poly(U) binding splicing factor 60 Homo sapiens 114-117 26241176-12 2016 Additionally, Ad-FIR showed synergistic cell toxicity with X-ray in vitro and significantly increased the antitumor efficacy of carbon-ion irradiation in the xenograft mouse model of TE-2 cells (P=0.03, Mann-Whitney"s U-test) and was synergistic with the sensitization enhancement ratio (SER) value of 1.15. Carbon 128-134 poly(U) binding splicing factor 60 Homo sapiens 17-20 26241176-13 2016 Therefore, Ad-FIR increased the cell-killing activity of the carbon-ion beam that avoids late-phase severe adverse effects independently of the TP53 status in vitro. Carbon 61-67 poly(U) binding splicing factor 60 Homo sapiens 14-17 27290912-3 2016 Most of the pyridazinone derivatives are derived from substitution of the pyridazinone oxygen, nitrogen and C4/C5/C6 carbon positions. Carbon 117-123 complement C4A (Rodgers blood group) Homo sapiens 108-113 26774662-6 2016 When the G2-M phased cells were transferred with DNA-PKcs siRNA and ATM siRNA individually or treated with an inhibitor of either DNA-PKcs or ATM before carbon ion irradiation, the RIBE was effectively diminished. Carbon 153-159 ATM serine/threonine kinase Homo sapiens 68-71 26774662-6 2016 When the G2-M phased cells were transferred with DNA-PKcs siRNA and ATM siRNA individually or treated with an inhibitor of either DNA-PKcs or ATM before carbon ion irradiation, the RIBE was effectively diminished. Carbon 153-159 ATM serine/threonine kinase Homo sapiens 142-145 24879016-7 2014 HIF1alpha promoted high levels of glycolysis as well as increased oxidative phosphorylation in complete media, but oxidative phosphorylation was suppressed when supplied with single carbon source media. Carbon 182-188 hypoxia inducible factor 1, alpha subunit Mus musculus 0-9 24879016-8 2014 HIF2alpha, in contrast, supported oxidative phosphorylation in complete media or single glucose carbon source, but these cells were not responsive to glutamine nutrient sources. Carbon 96-102 endothelial PAS domain protein 1 Mus musculus 0-9 24793849-2 2014 A novel electrochemical sensing platform by modification of electroactive thionine functionalized graphene onto glass carbon electrode (Th/GRs/GCE) surface was constructed. Carbon 118-124 aminomethyltransferase Homo sapiens 143-146 24682935-1 2014 Metallacyclic complex [(Me2N)3Ta(eta(2)-CH2SiMe2NSiMe3)] (3) undergoes C-H activation in its reaction with H3SiPh to afford a Ta/mu-alkylidene/hydride complex, [(Me2N)2{(Me3Si)2N}Ta(mu-H)2(mu-C-eta(2)-CHSiMe2NSiMe3)Ta(NMe2)2] (4). Carbon 40-41 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 218-222 24666432-6 2014 Relative abundance patterns of carbon number are C10 > C11 > C12 ~ C13 for SCCPs and C14 > C15 > C16 C17 for MCCP with similarity to the profiles of samples from China, the biggest CPs producer in the world. Carbon 31-37 cytokine like 1 Homo sapiens 113-116 24399840-1 2014 Vitamin B9, commonly known as folate, is an essential cofactor for one-carbon metabolism that enters cells through three major specialized transporter molecules (RFC, FR, and PCFT), which differ in expression pattern, affinity for substrate, and ligand-binding pH dependency. Carbon 71-77 solute carrier family 46 member 1 Homo sapiens 175-179 24766786-4 2014 Since as little as 50 mug mL-1 of carbon nanotubes increase the tomato production by about 200%, they may be exploited to enhance the agriculture production in future. Carbon 34-40 L1 cell adhesion molecule Mus musculus 26-30 24757211-3 2014 However, when studying a conditionally regulated tpi knockdown mutant, we noticed that depletion of TPI reduced growth of M. tuberculosis in media containing a single carbon source but not in media that contained both a glycolytic and a gluconeogenic carbon source. Carbon 167-173 triosephosphate isomerase 1 Mus musculus 100-103 24757211-3 2014 However, when studying a conditionally regulated tpi knockdown mutant, we noticed that depletion of TPI reduced growth of M. tuberculosis in media containing a single carbon source but not in media that contained both a glycolytic and a gluconeogenic carbon source. Carbon 251-257 triosephosphate isomerase 1 Mus musculus 100-103 24757211-4 2014 We used such two-carbon-source media to isolate a tpi deletion (Deltatpi) mutant. Carbon 17-23 triosephosphate isomerase 1 Mus musculus 50-53 24504141-0 2014 Carbon ion irradiation of the human prostate cancer cell line PC3: a whole genome microarray study. Carbon 0-6 proprotein convertase subtilisin/kexin type 1 Homo sapiens 62-65 24675437-0 2014 Released plasmonic electric field of ultrathin tetrahedral-amorphous-carbon films coated Ag nanoparticles for SERS. Carbon 69-75 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 110-114 24648727-0 2014 Carbon nanotubes as VEGF carriers to improve the early vascularization of porcine small intestinal submucosa in abdominal wall defect repair. Carbon 0-6 vascular endothelial growth factor A Rattus norvegicus 20-24 24503220-9 2014 The largest variation in the amount of carbon and lipids was among ant subfamilies and species, while the largest variation in nitrogen was among ant genera. Carbon 39-45 solute carrier family 25 member 6 Homo sapiens 67-70 24525204-5 2014 Pancreatic uptake of (11)C-5-HTP in nonhuman primates was markedly decreased by inhibition of the enzyme dopa decarboxylase, which converts (11)C-5-HTP to (11)C-serotonin and increased after inhibition of monoamine oxidase-A, the main enzyme responsible for serotonin degradation. Carbon 25-26 monoamine oxidase A Homo sapiens 205-224 24425249-0 2014 NBS mediated nitriles synthesis through C=C double bond cleavage. Carbon 40-41 nibrin Homo sapiens 0-3 24425249-0 2014 NBS mediated nitriles synthesis through C=C double bond cleavage. Carbon 42-43 nibrin Homo sapiens 0-3 24425249-1 2014 An NBS mediated nitriles synthesis through C=C double bond cleavage has been developed. Carbon 43-44 nibrin Homo sapiens 3-6 24425249-1 2014 An NBS mediated nitriles synthesis through C=C double bond cleavage has been developed. Carbon 45-46 nibrin Homo sapiens 3-6 24533076-1 2014 BACKGROUND: Genome-wide association studies on components of the one-carbon metabolic pathway revealed that human vitamin B12 levels could be significantly influenced by variations in the fucosyltransferase 2 (FUT2), cubilin (CUBN), and transcobalamin-I (TCN1) genes. Carbon 69-75 transcobalamin 1 Homo sapiens 255-259 26580033-0 2014 Benchmarking Hydrogen and Carbon NMR Chemical Shifts at HF, DFT, and MP2 Levels. Carbon 26-32 tryptase pseudogene 1 Homo sapiens 69-72 24359449-0 2014 Structure and sorption properties of a zeolite-templated carbon with the EMT structure type. Carbon 57-63 IL2 inducible T cell kinase Homo sapiens 73-76 24359449-1 2014 An ordered microporous carbon material was prepared by the nanocasting process using the EMC-2 zeolite (EMT structure type) as a hard template. Carbon 23-29 ER membrane protein complex subunit 2 Homo sapiens 89-94 24359449-1 2014 An ordered microporous carbon material was prepared by the nanocasting process using the EMC-2 zeolite (EMT structure type) as a hard template. Carbon 23-29 IL2 inducible T cell kinase Homo sapiens 104-107 24444232-7 2014 When there was no bottoming out, peak acceleration was found to be proportional to m ( )(c-1).v ( )(2c), with c being approximately 0.25. Carbon 39-40 heterogeneous nuclear ribonucleoprotein C Homo sapiens 89-92 24365826-3 2014 This result shows speed gain of 459 and 112 times compared to the best CS implementations based on the MATLAB and C++, respectively, and that real-time CS SD-OCT imaging can finally be realized. Carbon 114-117 plexin A2 Homo sapiens 158-161 24274271-0 2014 Amperometric immunosensor for the determination of ceruloplasmin in human serum and urine based on covalent binding to carbon nanotubes-modified screen-printed electrodes. Carbon 119-125 ceruloplasmin Homo sapiens 51-64 24391791-1 2013 The spatial variability of soil organic carbon (SOC) and total nitrogen (STN) levels is important in both global carbon-nitrogen cycle and climate change research. Carbon 113-119 eukaryotic translation elongation factor 1 alpha 2 Homo sapiens 73-76 24771881-1 2013 We report here the successful fabrication of an improved Bi film wrapped single walled carbon nanotubes modified glassy carbon electrode (Bi/SWNTs/GCE) as a highly sensitive platform for ultratrace Cr(VI) detection through catalytic adsorptive cathodic stripping voltammetry (AdCSV). Carbon 87-93 aminomethyltransferase Homo sapiens 147-150 24771881-1 2013 We report here the successful fabrication of an improved Bi film wrapped single walled carbon nanotubes modified glassy carbon electrode (Bi/SWNTs/GCE) as a highly sensitive platform for ultratrace Cr(VI) detection through catalytic adsorptive cathodic stripping voltammetry (AdCSV). Carbon 120-126 aminomethyltransferase Homo sapiens 147-150 24036394-1 2013 The reaction catalyzed by squalene synthase (EC.2.5.1.21) that converts two molecules of farnesyl pyrophosphate to squalene represents a crucial branch point of the isoprenoid pathway in diverting carbon flux towards the biosynthesis of sterols. Carbon 197-203 squalene synthase 2 Glycine max 26-43 24313506-0 2013 Tip-enhanced Raman investigation of extremely localized semiconductor-to-metal transition of a carbon nanotube. Carbon 95-101 TOR signaling pathway regulator Homo sapiens 0-3 24056579-1 2013 Pre-introducing an extra carbon source into the porous aromatic framework of PAF-1 followed by thermolysis affords a new microporous carbon material, which demonstrates a CO2 uptake capacity of 93 cm(3) g(-1) (equivalent to 4.1 mmol g(-1) or 18.2 wt%) at 295 K and 1 bar. Carbon 25-31 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 77-82 24056579-1 2013 Pre-introducing an extra carbon source into the porous aromatic framework of PAF-1 followed by thermolysis affords a new microporous carbon material, which demonstrates a CO2 uptake capacity of 93 cm(3) g(-1) (equivalent to 4.1 mmol g(-1) or 18.2 wt%) at 295 K and 1 bar. Carbon 133-139 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 77-82 23661628-7 2013 Thus, the uptake of glucose and glutamine and utilization of the carbon sources derived from them, coordinated by HIF1alpha and c-Myc, are essential for osteoclast development and bone-resorbing activity through a balanced regulation of the nutrient and energy sensors, mTOR and AMPK. Carbon 65-71 MYC proto-oncogene, bHLH transcription factor Homo sapiens 128-133 24127525-6 2013 The mutation Y318S in hSlo1, which replaces Y with S as found in dSlo1, greatly diminishes the channel"s response to DHA with a 22-carbon chain whether beta1 or beta4 is absent or present. Carbon 131-137 slowpoke Drosophila melanogaster 65-70 24090091-7 2013 With increasing cluster size, the calculated vibrational frequency at the MP2/DZ level of theory shows a substantial blue shift for the asymmetric C-O stretch. Carbon 147-148 tryptase pseudogene 1 Homo sapiens 74-77 23998182-1 2013 Nanoporous LiNi1/3Co1/3Mn1/3O2 (NP-NCM) was synthesized by using vapour grown carbon fibers (VGCFs) as templates. Carbon 78-84 CWC22 spliceosome associated protein homolog Homo sapiens 35-38 28788340-1 2013 Carbon from jatropha seed hull (JC) was prepared to study the adsorption of cadmium ions (Cd2+) from aqueous solutions under various experimental conditions. Carbon 0-6 CD2 molecule Homo sapiens 90-93 23887622-7 2013 When the PPh3 analogues of complexes 1, i.e. the complexes [PtR(C^N)(PPh3)], 6, in which C^N is ppy or tpy = deprotonated 2-p-tolylpyridine, were reacted with one equivalent of CF3CO2H, the course of the reaction reversed and the M-C bonds of the cycloplatinated complexes are cleaved rather than the M-R bonds. Carbon 64-65 protein phosphatase 4 catalytic subunit Homo sapiens 9-13 23887622-7 2013 When the PPh3 analogues of complexes 1, i.e. the complexes [PtR(C^N)(PPh3)], 6, in which C^N is ppy or tpy = deprotonated 2-p-tolylpyridine, were reacted with one equivalent of CF3CO2H, the course of the reaction reversed and the M-C bonds of the cycloplatinated complexes are cleaved rather than the M-R bonds. Carbon 64-65 protein phosphatase 4 catalytic subunit Homo sapiens 69-73 23897002-1 2013 A poly(methylene blue)-modified glassy carbon electrode (PMB/GCE) was fabricated by electropolymerisation of methylene blue on a GCE and further utilized to investigate the electrochemical determination of 4-nitrophenol (4-NP) by cyclic voltammetry (CV), differential pulse voltammetry and chronocoulometry. Carbon 39-45 aminomethyltransferase Homo sapiens 61-64 23897002-1 2013 A poly(methylene blue)-modified glassy carbon electrode (PMB/GCE) was fabricated by electropolymerisation of methylene blue on a GCE and further utilized to investigate the electrochemical determination of 4-nitrophenol (4-NP) by cyclic voltammetry (CV), differential pulse voltammetry and chronocoulometry. Carbon 39-45 aminomethyltransferase Homo sapiens 129-132 23955374-1 2013 The complex [Nb(NMe2)2{(NMe2)C=N(t)Bu}{N(2,6-(i)Pr2C6H3)}] reacts with trialkylguanidines and undergoes a room temperature C-N bond cleavage of the iminocarbamoyl moiety. Carbon 29-30 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 16-20 23955374-1 2013 The complex [Nb(NMe2)2{(NMe2)C=N(t)Bu}{N(2,6-(i)Pr2C6H3)}] reacts with trialkylguanidines and undergoes a room temperature C-N bond cleavage of the iminocarbamoyl moiety. Carbon 29-30 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 24-28 24098965-2 2013 We used hydrophobic carbon nanotubes (CNTs) to construct the superhydrophobic hierarchical architecture of CNTs on silicon micropillar array (CNTs/Si-mup), which have a large contact angle of 153 to 155 and an ultralow SA of 3 to 5 . Carbon 20-26 major urinary protein, pseudogene Homo sapiens 150-153 23614645-1 2013 A significant increase of the ion yield at m/z 27 in collisions of low-energy ions of N2(+) and N(+) with hydrocarbon-covered room-temperature or heated surfaces of tungsten, carbon-fiber composite, and beryllium, not observed in analogous collisions of Ar(+), is ascribed to the formation of HCN(+) in heterogeneous reactions between N2(+) or N(+) and surface hydrocarbons. Carbon 111-117 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 293-296 23824605-0 2013 TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells. Carbon 43-49 transmembrane protein with EGF like and two follistatin like domains 2 Homo sapiens 0-6 23824605-4 2013 Here, we further characterize the functional interaction between TMEFF2 and SARDH and their link with one-carbon (1-C) metabolism and invasion. Carbon 106-112 transmembrane protein with EGF like and two follistatin like domains 2 Homo sapiens 65-71 23824605-7 2013 Real-time PCR and Western blot of subcellular fractions were used to study the effect of SARDH KD or TMEFF2 KD on expression of enzymes involved in one-carbon (1-C) metabolism and on TMEFF2 expression and localization. Carbon 152-158 transmembrane protein with EGF like and two follistatin like domains 2 Homo sapiens 101-107 23833763-1 2013 A simple, sensitive and reliable dopamine (DA) biosensor was developed based on a carbon dots (CDs) and chitosan (CS) composite film modified glassy carbon electrode (CDs-CS/GCE). Carbon 149-155 aminomethyltransferase Homo sapiens 167-177 23833763-2 2013 Under optimal conditions, the CDs-CS/GCE showed a better electrochemical response for the detection of DA than that of the glassy carbon electrode (GCE). Carbon 130-136 aminomethyltransferase Homo sapiens 30-40 23833763-2 2013 Under optimal conditions, the CDs-CS/GCE showed a better electrochemical response for the detection of DA than that of the glassy carbon electrode (GCE). Carbon 130-136 aminomethyltransferase Homo sapiens 37-40 23887873-5 2013 Tlr4(-/-) mice primed with TLR3 agonist polyinosinic:polycytidylic acid [poly(I:C)] to induce pro-caspase-11 expression were as susceptible as wild-type mice were to sepsis induced by E. coli LPS. Carbon 80-82 toll-like receptor 3 Mus musculus 27-31 24040106-9 2013 In addition, Uth1p affects cell sensitivity to compounds influencing cell wall composition and integrity (such as Calcofluor white and Congo red) differently when growing on fermentative versus respiratory carbon sources. Carbon 206-212 SUN family protein UTH1 Saccharomyces cerevisiae S288C 13-18 23811518-3 2013 In the present study, we cultivated iron-oxidizing bacteria (FeOB) and performed clone library analyses of functional genes related to carbon fixation and methane oxidization (cbbM and pmoA, respectively), in addition to bacterial and archaeal 16S rRNA genes, in freshwater iron-rich flocs at groundwater discharge points. Carbon 135-141 opsin 1, medium wave sensitive Homo sapiens 176-180 23820848-4 2013 The association between estimated black carbon levels and CIMT was estimated using mixed effects models to account for repeated outcome measures. Carbon 40-46 CIMT Homo sapiens 58-62 23820848-9 2013 A one-interquartile range increase in 1-year average black carbon (0.26 microg/m3) was associated with a 1.1% higher CIMT (95% CI: 0.4, 1.7%) based on a fully adjusted model. Carbon 59-65 CIMT Homo sapiens 117-121 23820848-10 2013 CONCLUSIONS: Annual mean black carbon concentration based on spatially resolved exposure estimates was associated with CIMT in a population of elderly men. Carbon 31-37 CIMT Homo sapiens 119-123 23788028-7 2013 In [{CH(ArO)3}Fe(NEt2)] (7) the C-H M bond angle is linear and involves a donor interaction. Carbon 5-6 tetraspanin 12 Homo sapiens 17-21 23911236-7 2013 Hk2 deletion in lung cancer cells suppressed glucose-derived ribonucleotides and impaired glutamine-derived carbon utilization in anaplerosis. Carbon 108-114 hexokinase 2 Mus musculus 0-3 23545069-3 2013 The SMBR was operated at a filtration flux of 20 L/m(2)h. The removal of dissolved organic carbon (DOC) and chemical oxygen demand (COD) with the addition of GAC was 95%. Carbon 91-97 glutaminase Homo sapiens 158-161 23802623-7 2013 Ionic properties are revealed for CCl3-Cl, which has an average C-Cl bond length near the median for the CCl3 radical and cation and a natural charge of +0.49 for the CCl3 subunit. Carbon 34-35 C-C motif chemokine ligand 3 Homo sapiens 105-109 23802623-7 2013 Ionic properties are revealed for CCl3-Cl, which has an average C-Cl bond length near the median for the CCl3 radical and cation and a natural charge of +0.49 for the CCl3 subunit. Carbon 34-35 C-C motif chemokine ligand 3 Homo sapiens 105-109 23874637-6 2013 Among the modified proteins with several unsaturated aldehydes of chain lengths varying from three to nine carbons, the MFG-E8(-/-) mice sera exclusively cross-reacted with the protein-bound 4-oxo-2-nonenal (ONE), a highly reactive aldehyde originating from the peroxidation of omega6 polyunsaturated fatty acids. Carbon 107-114 milk fat globule EGF and factor V/VIII domain containing Mus musculus 120-126 28811405-1 2013 The aim of this study was to determine the effects of main factors and interactions on the color removal performance from dye solutions using the electrocoagulation process enhanced by adsorption on Granular Activated Carbon (GAC). Carbon 218-224 glutaminase Homo sapiens 226-229 23449395-7 2013 The sensitizing effect of IL-24 on TLR3-induced apoptosis, mediated by influenza A virus or the TLR3-specific agonist poly(I:C), was also evident on tumor spheroids. Carbon 124-126 interleukin 24 Homo sapiens 26-31 23439872-4 2013 Strain-dependent down-regulation of several key one-carbon metabolism genes, including methionine adenosyltransferase 1alpha (Mat1a), cystathionine-beta-synthase (Cbs), methylenetetrahydrofolate reductase (Mthfr), adenosyl-homocysteinase (Ahcy), and methylenetetrahydrofolate dehydrogenase 1 (Mthfd1), was observed. Carbon 52-58 cystathionine beta-synthase Mus musculus 163-166 23737986-6 2013 Growth phenotypes of 17 combinatorial fadD mutants on different FAs, as sole carbon sources, indicated that the four new fadD homologues are involved in FA degradation, bringing the total number of P. aeruginosa fadD genes to six. Carbon 77-83 Fas (TNFRSF6)-associated via death domain Mus musculus 38-42 23737986-6 2013 Growth phenotypes of 17 combinatorial fadD mutants on different FAs, as sole carbon sources, indicated that the four new fadD homologues are involved in FA degradation, bringing the total number of P. aeruginosa fadD genes to six. Carbon 77-83 Fas (TNFRSF6)-associated via death domain Mus musculus 121-125 23737986-6 2013 Growth phenotypes of 17 combinatorial fadD mutants on different FAs, as sole carbon sources, indicated that the four new fadD homologues are involved in FA degradation, bringing the total number of P. aeruginosa fadD genes to six. Carbon 77-83 Fas (TNFRSF6)-associated via death domain Mus musculus 121-125 23737986-8 2013 Growth patterns of various fadD mutants on plant-based perfumery substances, citronellic and geranic acids, as sole carbon and energy sources indicated that fadD4 is also involved in the degradation of these plant-derived compounds. Carbon 116-122 Fas (TNFRSF6)-associated via death domain Mus musculus 27-31 23724145-9 2013 Transcription of a key enzyme in one-carbon metabolism, dihydrofolate reductase (DHFR) was greatly reduced by the long-term CSE treatment, potentially serving as a mechanism for the hypomethylation phenotype via a reduced supply of methyl donor. Carbon 37-43 dihydrofolate reductase Homo sapiens 56-79 23724145-9 2013 Transcription of a key enzyme in one-carbon metabolism, dihydrofolate reductase (DHFR) was greatly reduced by the long-term CSE treatment, potentially serving as a mechanism for the hypomethylation phenotype via a reduced supply of methyl donor. Carbon 37-43 dihydrofolate reductase Homo sapiens 81-85 23551709-0 2013 Granulocyte-colony stimulating factor-producing cervical cancers treated with carbon-ion irradiation. Carbon 78-84 colony stimulating factor 3 Homo sapiens 0-37 23551709-3 2013 We report two cases of G-CSF-producing uterine cervical cancer who were successfully treated with carbon-ion radiotherapy (C-ion RT). Carbon 98-104 colony stimulating factor 3 Homo sapiens 23-28 23456152-3 2013 of Li[N=C(NMe2)2] in THF at room temperature affords [Cp2Ln(mu-eta(1):eta(2)-L2)]2 (Ln = Y; L = N=C(NMe2)N=C(NMe2)2) and CpLn[N=C(NMe2)2](mu-eta(1):eta(2)-L)2LnCp2 (Ln = Dy) in moderated yields, respectively. Carbon 8-9 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 10-14 23233208-8 2013 Glycolate is a carbon-competing by-product during EG production in E. coli; blockage of glycoaldehyde glycolate reaction was also performed by disrupting the gene encoding aldehyde dehydrogenase, but from this approach, EG productivity was not improved but rather led to D-xylonate accumulation. Carbon 15-21 Aldehyde dehydrogenase Escherichia coli 174-196 22213190-9 2013 The downregulation of Mat1a and Mthfr genes was accompanied by marked functional alterations in one-carbon metabolism. Carbon 100-106 methylenetetrahydrofolate reductase Rattus norvegicus 32-37 23375091-2 2013 We have shown that positively charged bivalent imidazolium salts in which the two imidazolium groups are linked by an aliphatic chain of 20 or 22 carbons form potent inhibitors of purified human beta3-GalT5, using GlcNAcbeta-benzyl as acceptor substrate. Carbon 146-153 beta-1,3-galactosyltransferase 5 Homo sapiens 195-206 23274715-0 2013 Multi-walled carbon nanotube increases the excitability of hippocampal CA1 neurons through inhibition of potassium channels in rat"s brain slices. Carbon 13-19 carbonic anhydrase 1 Rattus norvegicus 71-74 23182905-5 2013 For relatively slow S(ATP), such as the moderate sigmoidal release model, c(w-ATP+ADP) was very low in certain flow regions with low wall shear stress. Carbon 30-31 WD and tetratricopeptide repeats 1 Homo sapiens 82-85 26408146-2 2016 Phosphoglycerate kinase (PGK; EC = 2.7.2.3) plays a major role for ATP production during glycolysis and 1, 3-bisphosphoglycerate production to participate in the Calvin cycle for carbon fixation in plants. Carbon 179-185 phosphoglycerate kinase, chloroplastic Nicotiana tabacum 0-23 26408146-2 2016 Phosphoglycerate kinase (PGK; EC = 2.7.2.3) plays a major role for ATP production during glycolysis and 1, 3-bisphosphoglycerate production to participate in the Calvin cycle for carbon fixation in plants. Carbon 179-185 phosphoglycerate kinase, chloroplastic Nicotiana tabacum 25-28 26535955-2 2015 Electronic structure calculations propose that the reaction of silylidyne with allene has no entrance barrier and is initiated by silylidyne addition to the pi electron density of allene either to one carbon atom (C1/C2) or to both carbon atoms simultaneously via indirect (complex forming) reaction dynamics. Carbon 201-207 heterogeneous nuclear ribonucleoprotein C Homo sapiens 214-219 26409105-2 2015 In this study, three parallel aerobic granular sludge reactors treating low-strength wastewater were established using granular activated carbon (GAC) of different sizes as the nucleating agent. Carbon 138-144 glutaminase Homo sapiens 146-149 26417023-1 2015 The two carboxylation reactions performed by phosphoenolpyruvate carboxylase (PEPC) and ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) are vital in the fixation of inorganic carbon for C4 plants. Carbon 185-191 phosphoenolpyruvate carboxykinase 1 Homo sapiens 45-76 26417023-1 2015 The two carboxylation reactions performed by phosphoenolpyruvate carboxylase (PEPC) and ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) are vital in the fixation of inorganic carbon for C4 plants. Carbon 185-191 phosphoenolpyruvate carboxykinase 1 Homo sapiens 78-82 26354256-1 2015 An electrochemical magneto Au nanoparticles/carbon paste electrodes (MAuNP/CPE) which is used for the determination of acetaminophen (AC) in real samples was developed. Carbon 44-50 carboxypeptidase E Homo sapiens 75-78 16667188-1 1989 A theoretical model of the composition of the inorganic carbon pool generated in C(4) leaves during steady-state photosynthesis was derived. Carbon 56-62 complement C4A (Rodgers blood group) Homo sapiens 81-85 16667188-4 1989 Under these circumstances the flux of carbon through the C(4) acid cycle would have to exceed the net rate of CO(2) assimilation by 15.5%. Carbon 38-44 complement C4A (Rodgers blood group) Homo sapiens 57-61 16667188-7 1989 The model suggests that as the net photosynthesis rate changes in C(4) plants, the level and distribution of the components of the inorganic carbon pool change in such a way that C(4) acid overcycling is maintained in an approximately constant ratio with respect to the net photosynthesis rate. Carbon 141-147 complement C4A (Rodgers blood group) Homo sapiens 66-70 26485042-1 2015 DNA methyltransferase 3B (DNMT3B) and methylenetetrahydrofolate reductase (MTHFR) are genes which encode enzymes critical to one-carbon metabolism. Carbon 129-135 DNA methyltransferase 3 beta Homo sapiens 0-24 26485042-1 2015 DNA methyltransferase 3B (DNMT3B) and methylenetetrahydrofolate reductase (MTHFR) are genes which encode enzymes critical to one-carbon metabolism. Carbon 129-135 DNA methyltransferase 3 beta Homo sapiens 26-32 16667188-7 1989 The model suggests that as the net photosynthesis rate changes in C(4) plants, the level and distribution of the components of the inorganic carbon pool change in such a way that C(4) acid overcycling is maintained in an approximately constant ratio with respect to the net photosynthesis rate. Carbon 141-147 complement C4A (Rodgers blood group) Homo sapiens 179-183 17769400-1 1989 The C(5) molecule has been identified in the infrared spectrum of the prototypical obscured carbon star, IRC+10216. Carbon 92-98 complement C5 Homo sapiens 4-8 26196067-6 2015 Compared with the NB treatment, the 2yrB treatment lowered soil total C by 44%, total N by 54%, HCl hydrolysable C and N by 48% and 59%, KMnO4 oxidizable C by 81%, microbial biomass C and N by 42% and 33%, cumulative CO2-C by 28%, NaOCl-non-oxidizable C and N by 41% and 51%, and charcoal-C by 17%, respectively. Carbon 0-1 complement C2 Homo sapiens 217-220 17769400-2 1989 In addition to their astrophysical importance, pure carbon chain molecules such as C(5) are of interest in the chemistry of flames and propellants. Carbon 52-58 complement C5 Homo sapiens 83-87 26340696-2 2015 The reaction afforded a variety of dimeric 2-oxindoles with a C-3/C-5" linkage having an all-carbon quaternary center at the pseudobenzylic position in high yields. Carbon 93-99 complement C5 Homo sapiens 66-69 2709381-6 1989 The stereospecific attachment of all three alpha-halogenoses appears to occur by a Walden inversion (SN2 mechanism) at the C-1 carbon of the halogenose by the anionic N-1 of pyrazolo[3,4-b]pyridine. Carbon 127-133 heterogeneous nuclear ribonucleoprotein C Homo sapiens 123-126 2525050-6 1989 The absorption maxima of bovine artificial pigments formed by regenerating opsin with the 11-cis dihydro series of chromophores support a color regulation model for bovine rhodopsin in which the chromophore-binding site of the protein has two negative charges: one directly hydrogen bonded to the Schiff base nitrogen and another near carbon-13. Carbon 335-341 rhodopsin Bos taurus 172-181 26508036-5 2015 Carbon atom displacements almost completely account for the differences in the symmetric and asymmetric CCl2 stretching intensities of dichloromethane, 103.9 of the total calculated value of 105.2 km mol(-1). Carbon 0-6 C-C motif chemokine ligand 2 Homo sapiens 104-108 2917018-6 1989 Surprisingly, HLo-7 is highly active in reactivating human erythrocyte and rat diaphragm AChE inhibited by C(+)P(+/-)-and C(-)P(+/-)-soman, i.e. at least as active as HI-6, which is the most potent reactivator for soman-inhibited AChE reported so far. Carbon 122-126 acetylcholinesterase Rattus norvegicus 89-93 26316448-14 2015 SIGNIFICANCE: These results suggested that carbon-ion irradiation induced apoptosis through the p53 pathway in zebrafish eyes independent of ROS generation. Carbon 43-49 tumor protein p53 Danio rerio 96-99 26345349-4 2015 The evolution of the carbon environment towards tetrahedral CO4 units, thus resembling the crystal chemistry of silicon, is predicted at higher pressures. Carbon 21-27 complement C4A (Rodgers blood group) Homo sapiens 60-63 26417080-4 2015 Our results document a prominent cyclicity of ~9 My in the carbon cycle paced by changes in the seasonal dynamics of hydrological processes and long-term sea level fluctuations. Carbon 59-65 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 96-99 23668107-6 2013 The n-alkene homologues from C14 to C32 were detected with different peak carbon numbers ranging from 20 to 27 in different seasons. Carbon 74-80 chemokine like factor Homo sapiens 36-39 2906224-2 1988 It seems that parent compounds with free hydroxyl groups at C-5, C-7, C-3", C-4" and additionally at C-3 have the highest activity. Carbon 60-61 complement component C7 Oryctolagus cuniculus 65-68 2974722-5 1988 These results have been interpreted to suggest that the phosphorylated form of PGM catalyzes the phosphorylation of N6P at C-1. Carbon 123-124 phosphoglucomutase-1 Oryctolagus cuniculus 79-82 23207903-1 2013 Adr1 and Cat8 are nutrient-regulated transcription factors in Saccharomyces cerevisiae that coactivate genes necessary for growth in the absence of a fermentable carbon source. Carbon 162-168 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 9-13 26481997-2 2015 To improve the stability and sensitivity of glutamate sensors, an electrode modified with glutamate dehydrogenase (GDH)/Ni-Pd/core-shell nanoparticles was developed using the thermal polymerization of acrylamide (AM) to immobilize the synthesized Ni-Pd/core-shell nanoparticles onto a glassy carbon electrode (GCE). Carbon 292-298 glutamate dehydrogenase 1 Homo sapiens 115-118 3138949-8 1988 The finding of 12S oxygenation represents the first evidence that a lipoxygenase can control a reaction centered on the 10-carbon of an arachidonoyl phospholipid. Carbon 123-129 polyunsaturated fatty acid lipoxygenase ALOX15 Oryctolagus cuniculus 68-80 26355965-3 2015 In this sequence, fully diastereoselective hydrogeneration of the endocyclic carbon double bond in the cyclopentenone ring was key, generating a new stereogenic center (C-2 in 1a). Carbon 77-83 complement C2 Homo sapiens 169-172 26246317-0 2015 ATR signaling cooperates with ATM in the mechanism of low dose hypersensitivity induced by carbon ion beam. Carbon 91-97 ATM serine/threonine kinase Homo sapiens 30-33 26246317-8 2015 Interestingly, the early G2/M arrest could still be observed in ATM deficient/mutant cells with an effect of ATR signaling, which was discovered to function in an LET-dependent manner, even as low as 0.2Gy for carbon ion radiation. Carbon 210-216 ATM serine/threonine kinase Homo sapiens 64-67 26246317-10 2015 These data demonstrate that ATR pathway may cooperate with ATM in the mechanism of low dose hypersensitivity induced by carbon ion beam. Carbon 120-126 ATM serine/threonine kinase Homo sapiens 59-62 23359425-4 2013 To address this possibility, we overexpressed the ERR2 and ERR3 genes individually in a double-null yeast strain lacking ENO1 and ENO2, and showed that either ERR2 or ERR3 could complement the growth defect in this strain when cells are grown in medium with glucose as the carbon source. Carbon 273-279 phosphopyruvate hydratase ERR3 Saccharomyces cerevisiae S288C 59-63 23359425-4 2013 To address this possibility, we overexpressed the ERR2 and ERR3 genes individually in a double-null yeast strain lacking ENO1 and ENO2, and showed that either ERR2 or ERR3 could complement the growth defect in this strain when cells are grown in medium with glucose as the carbon source. Carbon 273-279 phosphopyruvate hydratase ERR3 Saccharomyces cerevisiae S288C 167-171 23212076-3 2013 Expression of PK type M2 (PKM2) is increased and facilitates lactate production in cancer cells, which determines whether the glucose carbons are degraded to pyruvate and lactate or are channeled into synthetic processes. Carbon 134-141 pyruvate kinase M1/2 Homo sapiens 14-24 23212076-3 2013 Expression of PK type M2 (PKM2) is increased and facilitates lactate production in cancer cells, which determines whether the glucose carbons are degraded to pyruvate and lactate or are channeled into synthetic processes. Carbon 134-141 pyruvate kinase M1/2 Homo sapiens 26-30 3062381-0 1988 Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases. Carbon 28-34 transcriptional regulator GAL3 Saccharomyces cerevisiae S288C 22-26 22885693-6 2013 Based on the obtained results, we created a new pDNA production strain starting from MG1655 by knocking out the pgi gene in order to redirect carbon flux to the pentose phosphate pathway, enhance nucleotide synthesis, and, consequently, increase pDNA production. Carbon 142-148 glucose-6-phosphate isomerase Escherichia coli str. K-12 substr. MG1655 112-115 26057944-1 2015 In this paper, we chose rice husk as raw material and synthesized successfully porous carbon loaded with silver nanoparticles (RH-Ag) composites by simple and cost-effective method. Carbon 86-92 Rh associated glycoprotein Homo sapiens 127-132 2897141-9 1988 Interestingly, NK 1.1-depleted donor graft recipients had a significantly increased mortality in comparison with control groups receiving C"-treated grafts (P = 0.04) or anti-Thy 1.2 plus C"-treated grafts (P less than 0.05). Carbon 138-140 tachykinin receptor 1 Homo sapiens 15-19 26398421-1 2015 An electrochemical sensor was prepared using Au nanoparticles and reduced graphene successfully decorated on the glassy carbon electrode (Au/RGO/GCE) through an electrochemical method which was applied to detect Sunset Yellow (SY). Carbon 120-126 aminomethyltransferase Homo sapiens 145-148 27682106-8 2015 Mutants lacking the C-terminal bipartite motif exhibited reduced growth rates on starch as the sole carbon and energy source; therefore, association of AmyA with the membrane improves carbohydrate utilization. Carbon 100-106 glycoside hydrolase family 57 protein Saccharolobus solfataricus 152-156 23662055-0 2013 Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis. Carbon 60-66 heart and neural crest derivatives expressed 2 Mus musculus 98-101 2897141-9 1988 Interestingly, NK 1.1-depleted donor graft recipients had a significantly increased mortality in comparison with control groups receiving C"-treated grafts (P = 0.04) or anti-Thy 1.2 plus C"-treated grafts (P less than 0.05). Carbon 188-190 tachykinin receptor 1 Homo sapiens 15-19 22949066-0 2013 A B3LYP and MP2(full) theoretical investigation into the strength of the C-NO2 bond upon the formation of the molecule-cation interaction between Na+ and the nitro group of nitrotriazole or its methyl derivatives. Carbon 73-74 tryptase pseudogene 1 Homo sapiens 12-15 26356530-2 2015 PGK1 plays a key role in coordinating glycolytic energy production with one-carbon metabolism, serine biosynthesis, and cellular redox regulation. Carbon 76-82 phosphoglycerate kinase 1 Homo sapiens 0-4 22949066-1 2013 The changes of bond dissociation energy (BDE) in the C-NO2 bond and nitro group charge upon the formation of the molecule-cation interaction between Na+ and the nitro group of 14 kinds of nitrotriazoles or methyl derivatives were investigated using the B3LYP and MP2(full) methods with the 6-311++G**, 6-311++G(2df,2p) and aug-cc-pVTZ basis sets. Carbon 53-54 tryptase pseudogene 1 Homo sapiens 263-266 2896189-11 1987 This indicates that the electron density, and hence the nucleophilicity, of the 4a-carbon is elevated in the purple intermediate relative to free reduced DAO. Carbon 83-89 D-amino acid oxidase Homo sapiens 154-157 23280662-5 2012 As an example for the COB approach, we present the (1)H -(13)C-COB-INEPT with transfer of approximately 99% over the full carbon and proton bandwidth and (1)J(CH) -couplings in the range of 120-250 Hz, which have been optimized using efficient algorithms derived from optimal control theory. Carbon 122-128 metabolism of cobalamin associated B Homo sapiens 22-25 23280662-5 2012 As an example for the COB approach, we present the (1)H -(13)C-COB-INEPT with transfer of approximately 99% over the full carbon and proton bandwidth and (1)J(CH) -couplings in the range of 120-250 Hz, which have been optimized using efficient algorithms derived from optimal control theory. Carbon 122-128 metabolism of cobalamin associated B Homo sapiens 63-66 26189358-4 2015 Rotation about the C-C bond with concomitant rupture of the E-E bond leads to the 1,2-disubstituted ethanes, which have terminal E(NPh2) groups. Carbon 19-20 neurexophilin 2 Homo sapiens 131-135 26345643-1 2015 The fixed-dose combination (FDC) elvitegravir/cobicistat/emtricitabine/tenofovir (EVG/c/FTC/TDF) is a once-daily, single-tablet regimen containing an integrase strand transfer inhibitor and a pharmacoenhancer (cobicistat) associated with two nucleos(t)ide reverse transcriptase inhibitors. Carbon 15-16 sex determining region Y Homo sapiens 92-95 26345643-5 2015 Furthermore, EVG/c/FTC/TDF exhibited an excellent tolerability profile, with a safer lipid profile, and despite the indication of its use in subjects with an estimated creatinine clearance >70 mL/min, recent data demonstrated that EVG/c/FTC/TDF determined a reduction in estimated glomerular filtration rate (GFR) but not a reduction of actual GFR. Carbon 17-18 sex determining region Y Homo sapiens 244-247 25794957-0 2015 A carbon nanofiber-based label free immunosensor for high sensitive detection of recombinant bovine somatotropin. Carbon 2-8 somatotropin Bos taurus 100-112 25794957-1 2015 A carbon nanofiber-based label free electrochemical immunosensor for sensitive detection of recombinant bovine somatotropin (rbST) was developed. Carbon 2-8 somatotropin Bos taurus 111-123 25959385-5 2015 In the miRNA array of the cells treated with poly(I:C), upregulation of miR-187, -146a, -574, -4274, -4433, -4455 and -4750, and downregulation of miR-4785 by more than twofold compared to the control were observed. Carbon 52-53 microRNA 187 Homo sapiens 72-79 26087936-3 2015 The results indicated that just the two carbon-20(22) double-bond-type ginsenosides showed strong inhibiting activity on melanogenesis through reducing tyrosinase activity. Carbon 40-46 tyrosinase Mus musculus 152-162 26141993-6 2015 It is a carbon terminal protein fragment obtained after cleavage from the carbon terminus of collagen XVIII. Carbon 8-14 collagen type XVIII alpha 1 chain Homo sapiens 93-107 26141993-6 2015 It is a carbon terminal protein fragment obtained after cleavage from the carbon terminus of collagen XVIII. Carbon 74-80 collagen type XVIII alpha 1 chain Homo sapiens 93-107 25966382-1 2015 An amperometric glucose biosensor based on direct electron transfer of glucose oxidase (GOD) self-assembled on the surface of partially unzipped carbon nanotubes (PUCNTs) modified glassy carbon electrode (GCE) has been successfully fabricated. Carbon 145-151 aminomethyltransferase Homo sapiens 205-208 25966382-1 2015 An amperometric glucose biosensor based on direct electron transfer of glucose oxidase (GOD) self-assembled on the surface of partially unzipped carbon nanotubes (PUCNTs) modified glassy carbon electrode (GCE) has been successfully fabricated. Carbon 187-193 aminomethyltransferase Homo sapiens 205-208 26160593-5 2015 Spexin injection increased the velocity of carbon powder propulsion in small intestine and decreased the glass beads expulsion time in distal colon in mice. Carbon 43-49 spexin hormone Mus musculus 0-6 26025532-8 2015 No obvious differences were observed in the seed-reserve of the wild-type and fln2-4 by comparing their seed size and dark-germination, indicating that the defective carbon fixation may account for the energy deficit in fln2-4 during its early seedling growth. Carbon 166-172 fructokinase-like protein Arabidopsis thaliana 220-226 25955505-4 2015 These hydrogen bonds acted as the electron tunnel to transfer electrons from Mb"s active sites to the underlying glassy carbon electrode. Carbon 120-126 myoglobin Homo sapiens 77-79 25925006-11 2015 CONCLUSIONS: The deletion of competitive pathways to reduce the outflow of carbon, including ILV1 deletion, is an important strategy for increasing isobutanol production by S. cerevisiae. Carbon 75-81 threonine ammonia-lyase ILV1 Saccharomyces cerevisiae S288C 93-97 25928034-0 2015 The histone methyltransferase SDG8 mediates the epigenetic modification of light and carbon responsive genes in plants. Carbon 85-91 histone-lysine N-methyltransferase Arabidopsis thaliana 30-34 25928034-8 2015 Importantly, 64% of these SDG8 targets are responsive to light and/or carbon signals. Carbon 70-76 histone-lysine N-methyltransferase Arabidopsis thaliana 26-30 25945129-7 2015 Notably, promoter DNA methylation emerged as a novel regulatory mechanism for the transcriptional repression of genes controlling the retinol metabolism (ADH1A, ADH1B, ADH6, CYP3A43, CYP4A22, RDH16), iron homeostasis (HAMP), one-carbon metabolism (SHMT1), and genes with a putative, newly identified function as tumor suppressors (FAM107A, IGFALS, MT1G, MT1H, RNF180). Carbon 229-235 alcohol dehydrogenase 1A (class I), alpha polypeptide Homo sapiens 154-159 25577261-8 2015 It was accompanied by the normalization of the gene expression of BHMT, GNMT and MGAT, which code for key enzymes of one-carbon metabolism related to liver fat accumulation. Carbon 121-127 glycine N-methyltransferase Rattus norvegicus 72-76 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 109-116 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 17-23 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 109-116 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 121-127 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 109-116 Acyl-coenzyme A oxidase acox-1.3 Caenorhabditis elegans 128-134 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 217-224 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 17-23 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 217-224 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 121-127 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 217-224 Acyl-coenzyme A oxidase acox-1.3 Caenorhabditis elegans 128-134 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 217-224 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 17-23 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 217-224 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 121-127 25775534-6 2015 Specifically, an ACOX-1 homodimer controls the production of ascarosides with side chains with nine or fewer carbons, an ACOX-1/ACOX-3 heterodimer controls the production of those with side chains with seven or fewer carbons, and an ACOX-2 homodimer controls the production of those with omega-side chains with less than five carbons. Carbon 217-224 Acyl-coenzyme A oxidase acox-1.3 Caenorhabditis elegans 128-134 25678041-6 2015 For application, the Mn-doped CdS QDs were coated on the surface of a glassy carbon electrode and functionalized with a cell surface carbohydrate-specific ligand (3-aminophenylboronic acid). Carbon 77-83 CDP-diacylglycerol synthase 1 Homo sapiens 30-33 25554959-4 2015 Single crystal X-ray structural analysis of compound 17 evidenced that the configuration about CN double bond is syn to C-5 carbon (E-form). Carbon 124-130 complement C5 Homo sapiens 120-123 25699577-1 2015 A highly enantioselective bromocyclization of allylic amides with N-bromosuccinimide (NBS) was developed with DTBM-BINAP as a catalyst, affording chiral oxazolines with a tetrasubstituted carbon center in high yield with up to 99% ee. Carbon 188-194 nibrin Homo sapiens 86-89 25677305-2 2015 Serine hydroxymethyltransferase (SHMT), the enzyme providing one-carbon units by converting serine and tetrahydrofolate (H4 PteGlu) to glycine and 5,10-CH2 -H4 PteGlu, therefore represents a target of interest in developing new chemotherapeutic drugs. Carbon 65-71 serine hydroxymethyltransferase 1 Homo sapiens 0-31 25677305-2 2015 Serine hydroxymethyltransferase (SHMT), the enzyme providing one-carbon units by converting serine and tetrahydrofolate (H4 PteGlu) to glycine and 5,10-CH2 -H4 PteGlu, therefore represents a target of interest in developing new chemotherapeutic drugs. Carbon 65-71 serine hydroxymethyltransferase 1 Homo sapiens 33-37 26204391-6 2015 ARs with alkyl chains containing 5-12 carbon atoms at concentrations of 0.1-1.0 muM weakly induced soxS-gene expression, whereas 1-10 mM repressed it. Carbon 38-44 DNA-binding transcriptional dual regulator SoxS Escherichia coli str. K-12 substr. MG1655 99-103 25582782-7 2015 The empirical relationships between the organic-carbon normalized sorption coefficient (Koc) and water solubility and between Koc and the octanol-water partition coefficient (Kow) were established. Carbon 48-54 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 88-91 27682076-3 2015 C-1 compounds such as methane and methanol are important intermediates in the deep subsurface carbon cycle, and electron acceptors such as sulphate are critical components of oxidation processes. Carbon 94-100 heterogeneous nuclear ribonucleoprotein C Homo sapiens 0-3 25231738-2 2015 In this work, integration of the dynamics of organic carbon (OC) and OPs in an overall experimental framework is first proposed and adopted to validate the applicability of the COP-Compost model and to calibrate the model parameters on the basis of what has been achieved with the COP-Compost model. Carbon 53-59 caspase recruitment domain family member 16 Homo sapiens 177-180 25743134-8 2015 Interesting reagents such as PARP and HSP90 inhibitors have been proposed as cancer cell- specific sensitizers for carbon-ion irradiation during basic biological studies, especially those from the Research Project with Heavy Ions at NIRS-HIMAC. Carbon 115-121 heat shock protein 90 alpha family class A member 1 Homo sapiens 38-43 24508027-3 2015 While dimeric PKM2 diverts glucose metabolism towards anabolism through aerobic glycolysis, tetrameric PKM2 promotes the flux of glucose-derived carbons for ATP production via oxidative phosphorylation. Carbon 145-152 pyruvate kinase M1/2 Homo sapiens 103-107 23064226-5 2012 This reduction in PKM2 activity shifts cells to a fuel-efficient mode in which more pyruvate is diverted to the mitochondria and more glucose-derived carbon is channelled into serine biosynthesis to support cell proliferation. Carbon 150-156 pyruvate kinase M1/2 Homo sapiens 18-22 23024004-2 2012 Theoretical calculations and kinetic data support a mechanism through which the isomerization proceeds through FMN-mediated hydride addition onto exo-Cbeta, followed by hydride abstraction from endo-Cbeta", which is in line with the well-established C=C bond bioreduction of OYEs. Carbon 150-151 formin 1 Homo sapiens 111-114 23024004-2 2012 Theoretical calculations and kinetic data support a mechanism through which the isomerization proceeds through FMN-mediated hydride addition onto exo-Cbeta, followed by hydride abstraction from endo-Cbeta", which is in line with the well-established C=C bond bioreduction of OYEs. Carbon 199-200 formin 1 Homo sapiens 111-114 22696309-4 2012 The MP2/aug-cc-pVTZ c-C(3)H(2) H-F complex potential energy surface turns out to be an asymmetric deep single well, while asymmetric double wells are found for the c-C(3)H(2) H-Cl and c-C(3)H(2) H-Br complexes, with an energy barrier of 4.1 kcal mol(-1) for proton transfer along the hydrogen bond in the latter complex. Carbon 168-169 tryptase pseudogene 1 Homo sapiens 4-7 22885800-3 2012 Tris(triphenylphosphine)rhodium(I) carbonyl hydride M(H)(CO)(PPh(3))(3) (M = Rh, Ir) cleaved one of the E-Me bonds of {o-(Ph(2)P)C(6)H(4)}(2)EMe(2) exclusively to afford the trigonal bipyramidal (TBP) complexes, [PEP]M(CO)(PPh(3)). Carbon 57-58 progestagen associated endometrial protein Homo sapiens 213-216 22037862-6 2012 In addition, carbon utilization studies were also carried out with bacterial isolates LH1, LH2, and LH4 belonging to the genus Cellulosimicrobium, Bacillus, and Ralstonia, respectively, isolated from the snow samples. Carbon 13-19 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Homo sapiens 86-89 22690903-5 2012 Only lipopolysaccharide (LPS), poly(I:C), Pam3CSK4 and MALP-2 could induce the production of IL-6, IL-8 and MCP-1 by adipocytes. Carbon 38-39 C-C motif chemokine ligand 2 Homo sapiens 108-113 21789569-2 2012 The farmland waste corncob was found in this study to be the best carbon source for the production of beta-glucosidase by Aspergillus niger. Carbon 66-72 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1a, chloroplastic Triticum aestivum 102-118 22495737-9 2012 CONCLUSIONS: Glucomannan hydrolysates produced with either mannanase or cellulase enzymes were effective growth promoters (carbon sources) of LAB. Carbon 123-129 mannosidase beta Homo sapiens 59-68 22349003-1 2012 We report on the direct electrochemistry of myoglobin (Mb) immobilized on a composite matrix based on chitosan (CHIT) and titanium carbide nanoparticles (TiC NPs) underlying on glassy carbon electrode (GCE). Carbon 184-190 myoglobin Homo sapiens 44-53 22461383-6 2012 The Mulliken charges on certain carbon atoms, the log P value and the total energy showed significant relationships with binding activities to the housefly GABA receptor in these two QSAR models. Carbon 32-38 GABA type A receptor-associated protein Homo sapiens 156-169 22942379-1 2012 Most life is ultimately sustained by photosynthesis and its rate-limiting carbon fixing enzyme, ribulose-1,5-bis-phosphate carboxylase/oxygenase (Rubisco). Carbon 74-80 ribulose bisphosphate carboxylase small subunit, chloroplastic Zea mays 96-144 22942379-1 2012 Most life is ultimately sustained by photosynthesis and its rate-limiting carbon fixing enzyme, ribulose-1,5-bis-phosphate carboxylase/oxygenase (Rubisco). Carbon 74-80 ribulose bisphosphate carboxylase small subunit, chloroplastic Zea mays 146-153 22849540-3 2012 RESULTS: Here, we show that expression of adhC is maximally induced under conditions of high oxygen tension as well as specifically with glucose as a carbon source. Carbon 150-156 S-(hydroxymethyl)glutathione dehydrogenase Haemophilus influenzae Rd KW20 42-46 22638969-4 2012 METHODS: A SACI-MS approach was used to investigate the quantitative in vivo phosphorylation of the cyclin-dependent kinase inhibitor Sic1, a low-abundance protein of Saccharomyces cerevisiae, which is phosphorylated on Ser201 by casein kinase 2 (CK2) and compared its phosphorylation status in cells growing in two different carbon sources (glucose or ethanol). Carbon 326-332 cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1 Saccharomyces cerevisiae S288C 134-138 22731822-11 2012 At medium-to-high concentration for the ocean, naturally derived dissolved organic carbon did not significantly affect the baseline-corrected electrode response of Mn(II) and Fe(II), but did significantly affect the response of S(-II). Carbon 83-89 transcription elongation factor A1 Homo sapiens 228-233 22579386-9 2012 Growth on xylose and xylose-fermenting ability were slightly influenced by deletion of NQM1 or TKL2 when xylose was used as the sole carbon source. Carbon 133-139 transketolase TKL2 Saccharomyces cerevisiae S288C 95-99 22078968-0 2012 Removal of trace organic contaminants by a membrane bioreactor-granular activated carbon (MBR-GAC) system. Carbon 82-88 glutaminase Homo sapiens 94-97 22717749-1 2012 Granular activated carbon (GAC) is an alternative filter substrate for municipal water treatment as it provides a high surface area suitable for microbial colonization. Carbon 19-25 glutaminase Homo sapiens 27-30 22623105-5 2012 We compared, using a proteomic approach, the protein pattern of SCO1 null mutant strain and wild-type BY4741 strain grown on fermentable and on nonfermentable carbon sources. Carbon 159-165 Cu-binding protein SCO1 Saccharomyces cerevisiae S288C 64-68 22623105-10 2012 Our results suggest that on nonfermentable carbon source, the lack of Sco1p causes a metabolic shift from respiration to fermentation. Carbon 43-49 Cu-binding protein SCO1 Saccharomyces cerevisiae S288C 70-75 22640729-9 2012 Additional rational design to reduce glycerol production by GPD2 deletion altered the carbon fluxes back to ethanol and significantly reduced 2,3-butanediol production. Carbon 86-92 glycerol-3-phosphate dehydrogenase (NAD(+)) GPD2 Saccharomyces cerevisiae S288C 60-64 26286791-0 2012 Carbon-Detected (15)N NMR Spin Relaxation of an Intrinsically Disordered Protein: FCP1 Dynamics Unbound and in Complex with RAP74. Carbon 0-6 general transcription factor IIF subunit 1 Homo sapiens 124-129 22331892-2 2012 During this interval of global warming, the decay of ice sheets caused global mean sea level to rise by approximately 80 m; terrestrial and marine ecosystems experienced large disturbances and range shifts; perturbations to the carbon cycle resulted in a net release of the greenhouse gases CO(2) and CH(4) to the atmosphere; and changes in atmosphere and ocean circulation affected the global distribution and fluxes of water and heat. Carbon 228-234 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 83-86 22469824-3 2012 Such an electron-deficient bonding leaves an empty orbital which enables penta- or hexa-coordinated carbon atom. Carbon 100-106 hexosaminidase subunit alpha Homo sapiens 83-87 22467566-1 2012 Four- and five-bond heteronuclear J-couplings between the hydrogen H-8 and carbons C-6 and C-2 in a series of 7- and 9-benzyl substituted purine derivaties with variuous substituents in positions 2 and 6 were studied by coupled (13) C NMR and H,C-HMBC experiments and by DFT calculations. Carbon 75-82 complement C2 Homo sapiens 91-94 23576844-4 2012 Cyclic voltammetry of Mb-GO-Nafion films showed a pair of well defined, quasi-reversible peaks at about -0.312 V vs saturated calomel electrode (SCE) at pH 5.5, corresponding to direct electron transfer (DET) between Mb and the glassy carbon electrode. Carbon 235-241 myoglobin Homo sapiens 22-24 22283453-1 2012 A method to convert 2-hydroxy glycal ester to the corresponding 2-deoxy-2-C-alkyl glycal in a facile manner, through key reactions including (i) C-allylation at C-1, (ii) Wittig reaction, and (iii) Cope rearrangement of a 1,5-diene derivative, is reported. Carbon 74-75 heterogeneous nuclear ribonucleoprotein C Homo sapiens 161-164 22162368-1 2012 High-resolution imaging and spectroscopy of single CdSe nanowires and carbon nanotubes using tip-enhanced near-field optical microscopy increases the optical excitation and emission rates within a nanoscale sample volume. Carbon 70-76 TOR signaling pathway regulator Homo sapiens 93-96 22222202-0 2012 EGF-functionalized single-walled carbon nanotubes for targeting delivery of etoposide. Carbon 33-39 epidermal growth factor Homo sapiens 0-3 22100631-11 2012 There are also two enzymes within the ALDH1 family that play an important role both in ethanol metabolism and the folate one-carbon pathway. Carbon 125-131 aldehyde dehydrogenase 1 family member A1 Homo sapiens 38-43 22265562-2 2012 The electroanalytical performance for the determination of Cd(II) on the tin-coated carbon paste electrode(SnF-CPE) was better than that on the carbon paste electrode. Carbon 84-90 carboxypeptidase E Homo sapiens 111-114 22129100-1 2012 C(7)H(12)(2+) (1), the prototype hexacoordinate carbonium dication was found to be a viable minimum at the MP2/6-31G** and MP2/cc-pVTZ levels. Carbon 48-57 tryptase pseudogene 1 Homo sapiens 107-110 22132833-0 2012 Different hierarchical nanostructured carbons as counter electrodes for CdS quantum dot solar cells. Carbon 38-45 CDP-diacylglycerol synthase 1 Homo sapiens 72-75 22132833-1 2012 CdS quantum dot sensitized solar cells based on TiO(2) photoanode and nanostructured carbon as well as Pt as counter electrodes using iodide/triiodide and polysulfide electrolytes were fabricated to improve the efficiency and reduce the cost of solar cells. Carbon 85-91 CDP-diacylglycerol synthase 1 Homo sapiens 0-3 22031784-7 2012 The glucose, but not insulin, AUC was lowered with Vit E/C supplementation. Carbon 32-33 vitrin Rattus norvegicus 51-54 22021637-16 2012 Dimethyl and tetramethyl FAME, with branches separated by at least one methylene group, yield fragment on both sides of the sites of methyl branches that are more than 6 C away from the carboxyl carbon. Carbon 195-201 benign adult familial myoclonic epilepsy 1 Homo sapiens 25-29 22172286-4 2012 In this study, we propose to spectrally separate acetate C1 and glutamate C5 by a two-step J-editing technique after introducing homonuclear (13)C-(13)C scalar coupling between carboxylic/amide carbons and aliphatic carbons. Carbon 194-201 heterogeneous nuclear ribonucleoprotein C Homo sapiens 57-76 22172286-4 2012 In this study, we propose to spectrally separate acetate C1 and glutamate C5 by a two-step J-editing technique after introducing homonuclear (13)C-(13)C scalar coupling between carboxylic/amide carbons and aliphatic carbons. Carbon 216-223 heterogeneous nuclear ribonucleoprotein C Homo sapiens 57-76 22018726-1 2012 The enzymes folylpolyglutamate synthase (FPGS) and gamma-glutamyl hydrolase (GGH) are essential for determining intracellular folate availability for one-carbon metabolism (OCM) pathways. Carbon 154-160 folylpolyglutamate synthase Homo sapiens 12-39 22018726-1 2012 The enzymes folylpolyglutamate synthase (FPGS) and gamma-glutamyl hydrolase (GGH) are essential for determining intracellular folate availability for one-carbon metabolism (OCM) pathways. Carbon 154-160 folylpolyglutamate synthase Homo sapiens 41-45 22018726-1 2012 The enzymes folylpolyglutamate synthase (FPGS) and gamma-glutamyl hydrolase (GGH) are essential for determining intracellular folate availability for one-carbon metabolism (OCM) pathways. Carbon 154-160 gamma-glutamyl hydrolase Homo sapiens 51-75 22018726-1 2012 The enzymes folylpolyglutamate synthase (FPGS) and gamma-glutamyl hydrolase (GGH) are essential for determining intracellular folate availability for one-carbon metabolism (OCM) pathways. Carbon 154-160 gamma-glutamyl hydrolase Homo sapiens 77-80 23047667-5 2012 The reaction proceeds by way of a 1,2 carbon shift wherein the bond between C-2 and C-3 is cleaved and a new bond between C-1 and C-3 is formed, with C-1 moving to the C-2 position with an inverted configuration. Carbon 38-44 complement C2 Homo sapiens 76-87 23047667-5 2012 The reaction proceeds by way of a 1,2 carbon shift wherein the bond between C-2 and C-3 is cleaved and a new bond between C-1 and C-3 is formed, with C-1 moving to the C-2 position with an inverted configuration. Carbon 38-44 heterogeneous nuclear ribonucleoprotein C Homo sapiens 122-133 23047667-5 2012 The reaction proceeds by way of a 1,2 carbon shift wherein the bond between C-2 and C-3 is cleaved and a new bond between C-1 and C-3 is formed, with C-1 moving to the C-2 position with an inverted configuration. Carbon 76-77 heterogeneous nuclear ribonucleoprotein C Homo sapiens 122-133 23047667-5 2012 The reaction proceeds by way of a 1,2 carbon shift wherein the bond between C-2 and C-3 is cleaved and a new bond between C-1 and C-3 is formed, with C-1 moving to the C-2 position with an inverted configuration. Carbon 84-85 heterogeneous nuclear ribonucleoprotein C Homo sapiens 122-133 22778656-2 2012 Multi-walled carbon nanotubes were functionalized with three different cytochrome P450 isoforms (CYP1A2, CYP2B6, and CYP3A4). Carbon 13-19 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 97-103 22033659-1 2011 Ion transport membrane (ITM)-based oxy-combustion systems could potentially provide zero-emissions power generation with a significantly reduced thermodynamic penalty compared to conventional carbon capture applications. Carbon 192-198 solute carrier family 22 member 18 Homo sapiens 0-22 22033659-1 2011 Ion transport membrane (ITM)-based oxy-combustion systems could potentially provide zero-emissions power generation with a significantly reduced thermodynamic penalty compared to conventional carbon capture applications. Carbon 192-198 solute carrier family 22 member 18 Homo sapiens 24-27 22036122-4 2011 In the aqueous p-toluenesulfonic acid-d medium, C-6" and C-4" carbons of both alpha, and beta anomeric forms of D-cellobiose are significantly affected by increasing the sulfonic acid concentrations, and this may be due to a 1:1 interaction of p-toluenesulfonic acid-d with the C-6", C-4" region of the cellobiose molecule. Carbon 62-69 complement C4A (Rodgers blood group) Homo sapiens 57-60 22036122-4 2011 In the aqueous p-toluenesulfonic acid-d medium, C-6" and C-4" carbons of both alpha, and beta anomeric forms of D-cellobiose are significantly affected by increasing the sulfonic acid concentrations, and this may be due to a 1:1 interaction of p-toluenesulfonic acid-d with the C-6", C-4" region of the cellobiose molecule. Carbon 62-69 complement C4A (Rodgers blood group) Homo sapiens 284-287 21284409-5 2011 It describes that heteroatoms (oxygen atom connected with carbon atom) in the molecules are favourable for alpha-glucosidase inhibitory activity. Carbon 58-64 sucrase-isomaltase Homo sapiens 107-124 21967325-4 2011 The degradation of pentachlorophenol by potato PPO reaches a maximum at 298 K. After reaction for 1 h, the removal of both pentachlorophenol and total organic carbon is >70% with 6.0 units/mL potato PPO at pH 5.0 and 298 K. Pentachlorophenol can be degraded through dechlorination and ring-opening by potato PPO. Carbon 159-165 catechol oxidase B, chloroplastic Solanum tuberosum 47-50 21967325-4 2011 The degradation of pentachlorophenol by potato PPO reaches a maximum at 298 K. After reaction for 1 h, the removal of both pentachlorophenol and total organic carbon is >70% with 6.0 units/mL potato PPO at pH 5.0 and 298 K. Pentachlorophenol can be degraded through dechlorination and ring-opening by potato PPO. Carbon 159-165 catechol oxidase B, chloroplastic Solanum tuberosum 202-205 21967325-4 2011 The degradation of pentachlorophenol by potato PPO reaches a maximum at 298 K. After reaction for 1 h, the removal of both pentachlorophenol and total organic carbon is >70% with 6.0 units/mL potato PPO at pH 5.0 and 298 K. Pentachlorophenol can be degraded through dechlorination and ring-opening by potato PPO. Carbon 159-165 catechol oxidase B, chloroplastic Solanum tuberosum 202-205 22051678-0 2011 Arabian Sea tropical cyclones intensified by emissions of black carbon and other aerosols. Carbon 64-70 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 8-11 22051678-5 2011 Here we report an increase in the intensity of pre-monsoon Arabian Sea tropical cyclones during the period 1979-2010, and show that this change in storm strength is a consequence of a simultaneous upward trend in anthropogenic black carbon and sulphate emissions. Carbon 233-239 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 67-70 21745763-1 2011 The direct electron transfer of myoglobin (Mb) was achieved based on the immobilization of Mb/Silver nanoparticles (AgNPs) on glassy carbon electrode by multi-wall carbon nanotubes (MWNTs)-chitosan(Chit) film. Carbon 133-139 myoglobin Homo sapiens 32-41 21745763-1 2011 The direct electron transfer of myoglobin (Mb) was achieved based on the immobilization of Mb/Silver nanoparticles (AgNPs) on glassy carbon electrode by multi-wall carbon nanotubes (MWNTs)-chitosan(Chit) film. Carbon 164-170 myoglobin Homo sapiens 32-41 21844365-3 2011 We report here that cyanophages carry and express a Calvin cycle inhibitor, CP12, whose host homologue directs carbon flux from the Calvin cycle to the pentose phosphate pathway (PPP). Carbon 111-117 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 76-80 21914223-8 2011 Relative biological effectiveness (RBE) at 10% survival for U-CH1-N was about 2.45 for 70 keV/mum carbon and 3.86 for 200 keV/mum iron ions. Carbon 98-104 SUN domain containing ossification factor Homo sapiens 62-65 21880102-8 2011 Deuterium was completely exchanged with hydrogen at the substituted carbon atom (C-2) of the succinate adducts of n-alkanes, whereas it is retained in toluene-derived benzylsuccinate, regardless of the type of enzyme catalysing the fumarate addition reaction. Carbon 68-74 complement C2 Homo sapiens 81-84 21783081-1 2011 BACKGROUND: The aim of this cadaveric study was to assess the technical feasibility of inserting a novel interpositional pyrolytic carbon coated implant in the first MTP joint, determine the best surgical procedure for the implantation, and evaluate the dynamic behavior of the joint after surgery. Carbon 131-137 metallothionein 1B Homo sapiens 166-169 22165213-0 2011 [Temporal and spatial distribution of particulate organic carbon in the Yellow Sea and East China Sea in spring]. Carbon 58-64 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 79-82 22165213-0 2011 [Temporal and spatial distribution of particulate organic carbon in the Yellow Sea and East China Sea in spring]. Carbon 58-64 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 98-101 21697465-9 2011 HSV-2 R1 inhibited the interaction between the Toll/interleukin-1 receptor domain-containing adaptor-inducing beta interferon (IFN-beta) (TRIF) and RIP1, an interaction that is essential for apoptosis triggered by extracellular poly(I C) plus cycloheximide or TRIF overexpression. Carbon 237-238 receptor interacting serine/threonine kinase 1 Homo sapiens 148-152 21723372-4 2011 This study was conducted to determine if multi-walled carbon nanotubes (MWCNTs)-coated electrospun poly (l-lactic acid-co-caprolactone) (PLCL) nanofibers improved the neurite outgrowth of rat dorsal root ganglia (DRG) neurons and focal adhesion kinase (FAK) expression of PC-12 cells. Carbon 54-60 protein tyrosine kinase 2 Rattus norvegicus 230-251 21723372-4 2011 This study was conducted to determine if multi-walled carbon nanotubes (MWCNTs)-coated electrospun poly (l-lactic acid-co-caprolactone) (PLCL) nanofibers improved the neurite outgrowth of rat dorsal root ganglia (DRG) neurons and focal adhesion kinase (FAK) expression of PC-12 cells. Carbon 54-60 protein tyrosine kinase 2 Rattus norvegicus 253-256 21746787-15 2011 These data indicate that the increase in myofibrillar MPS for C+P could, potentially, be mediated through p70S6K, downstream of mTOR, which in turn may suppress the rise in eEF2 on translation elongation. Carbon 62-63 ribosomal protein S6 kinase B1 Homo sapiens 106-112 21746787-15 2011 These data indicate that the increase in myofibrillar MPS for C+P could, potentially, be mediated through p70S6K, downstream of mTOR, which in turn may suppress the rise in eEF2 on translation elongation. Carbon 62-63 eukaryotic translation elongation factor 2 Homo sapiens 173-177 21648046-4 2011 The vibrational modes related to the C=C stretching vibrations of TCE-TTF are analyzed assuming the occurrence of electron-molecular vibration coupling (EMV). Carbon 37-38 ras homolog family member H Homo sapiens 70-73 21648046-4 2011 The vibrational modes related to the C=C stretching vibrations of TCE-TTF are analyzed assuming the occurrence of electron-molecular vibration coupling (EMV). Carbon 39-40 ras homolog family member H Homo sapiens 70-73 21648046-5 2011 The presence of the antisymmetric C=C dimeric mode provides evidence that charge transfer takes place between TCE-TTF molecules belonging to neighboring polymeric networks. Carbon 34-35 ras homolog family member H Homo sapiens 114-117 21766921-6 2011 The C-C and C-S stretching mode of 1599 cm(-1) and the C-S-C and C-C-S bending mode of 472 cm(-1) strongly couple to the b(3)u highest occupied molecular orbital (HOMO) in TTF molecule. Carbon 4-5 ras homolog family member H Homo sapiens 172-175 21766921-6 2011 The C-C and C-S stretching mode of 1599 cm(-1) and the C-S-C and C-C-S bending mode of 472 cm(-1) strongly couple to the b(3)u highest occupied molecular orbital (HOMO) in TTF molecule. Carbon 6-7 ras homolog family member H Homo sapiens 172-175 21766921-6 2011 The C-C and C-S stretching mode of 1599 cm(-1) and the C-S-C and C-C-S bending mode of 472 cm(-1) strongly couple to the b(3)u highest occupied molecular orbital (HOMO) in TTF molecule. Carbon 6-7 ras homolog family member H Homo sapiens 172-175 21950073-4 2011 It this process, C-3 and C-4 atoms, which determine the "heavy" isotope composition of carbon of CO2 of the light-induced dark respiration component are split off from the hexose link of sucrose. Carbon 87-93 complement C4A (Rodgers blood group) Homo sapiens 25-28 25483146-4 2015 A uniform EC-SERS active Au/Ag substrate was developed by depositing nearly monodisperse gold and silver nanoparticles on the carbon working electrode surface of screen printed electrodes. Carbon 126-132 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 13-17 25278359-1 2014 A novel multi-scale web of carbon micro/nanofibers (ACF/CNF) was prepared by the catalytic chemical vapor deposition (CCVD), in which CeO2 and Cu nanoparticles (NPs) were in-situ incorporated during a synthesis step. Carbon 27-33 ACF Homo sapiens 52-55 25502225-1 2014 Recent work has highlighted glutaminase (GLS) as a key player in cancer cell metabolism, providing glutamine-derived carbon and nitrogen to pathways that support proliferation. Carbon 117-123 glutaminase Homo sapiens 28-39 25502225-1 2014 Recent work has highlighted glutaminase (GLS) as a key player in cancer cell metabolism, providing glutamine-derived carbon and nitrogen to pathways that support proliferation. Carbon 117-123 glutaminase Homo sapiens 41-44 25259775-7 2014 The resulting mean square displacements predicted by the c-HBBP model are consistent with the single-particle generalized Stokes-Einstein relation of linear passive microrheology. Carbon 32-33 TM2 domain containing 1 Homo sapiens 59-63 2959956-6 1987 From these and earlier results, we propose a possible mechanism in which the carbon-centered radical formed at C-5" by hydrogen atom abstraction by thiol-activated NCS-Chrom reacts anaerobically with misonidazole to form a nitroxyl-radical-adduct intermediate, which fragments to produce an oxy radical at C-5". Carbon 77-83 complement C5 Homo sapiens 111-114 25440664-1 2014 NiCoBP-doped multi-walled carbon nanotube (NiCoBP-MWCNT) was first synthesized by using induced electroless-plating method and functionalized with the biomolecules for highly efficient electrochemical immunoassay of prostate-specific antigen (PSA, used as a model analyte). Carbon 26-32 kallikrein related peptidase 3 Homo sapiens 216-241 25440664-1 2014 NiCoBP-doped multi-walled carbon nanotube (NiCoBP-MWCNT) was first synthesized by using induced electroless-plating method and functionalized with the biomolecules for highly efficient electrochemical immunoassay of prostate-specific antigen (PSA, used as a model analyte). Carbon 26-32 kallikrein related peptidase 3 Homo sapiens 243-246 21667299-3 2011 Yields for the (15)N- and (15)N/(13)C-labeled gp120s after affinity chromatography were 45 and 44 mg/l, respectively, with an average of over 80% isotope incorporation. Carbon 36-37 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 46-51 21553855-5 2011 Product yields for the wildtype Tbb TIM and monoTIM-catalyzed reactions of glycolaldehyde labeled with carbon-13 at the carbonyl carbon ([1-(13)C]-GA) at pD 7.0 in the presence of phosphite dianion and in its absence were determined by (1)H NMR spectroscopy [Go, M. K., Amyes, T. L., and Richard, J. P. (2009) Biochemistry 48, 5769-5778]. Carbon 103-109 triosephosphate isomerase Oryctolagus cuniculus 36-39 2959956-6 1987 From these and earlier results, we propose a possible mechanism in which the carbon-centered radical formed at C-5" by hydrogen atom abstraction by thiol-activated NCS-Chrom reacts anaerobically with misonidazole to form a nitroxyl-radical-adduct intermediate, which fragments to produce an oxy radical at C-5". Carbon 77-83 complement C5 Homo sapiens 306-309 25460352-4 2014 SOBP-penetration depth and extension was 35 mm +/-4 mm and 36 mm +/-5 mm for carbon ions and oxygen ions respectively. Carbon 77-83 sine oculis binding protein homolog Homo sapiens 0-4 3593384-1 1987 Isozyme 4-4 of rat liver glutathione S-transferase catalyzes the stereoselective addition of glutathione to the oxirane carbon of R-absolute configuration of cis-stilbene oxide, 2, to give 98 +/- 2% of the (1S,2S)-1,2-diphenyl-1-(S-glutathionyl)-2-hydroxyethane product with a turnover number (kc) of 0.22 s-1. Carbon 120-126 hematopoietic prostaglandin D synthase Rattus norvegicus 25-50 25411283-0 2014 Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region. Carbon 13-19 insulin like growth factor 2 Homo sapiens 107-111 25491822-3 2014 Compared to common carbon paste electrode, the electrochemical response was greatly improved for NADH electrooxidation at a surface of CdO/NP modified ionic liquid carbon paste electrode (IL/CdO/NP/CPE). Carbon 164-170 carboxypeptidase E Homo sapiens 198-201 21517100-4 2011 The system was composed of a CdS NC film on glassy carbon electrode (GCE) as ECL emitter attached an aptamer of thrombin. Carbon 51-57 CDP-diacylglycerol synthase 1 Homo sapiens 29-32 21232040-8 2011 Sensitivity of the EDL to C-547 dramatically decreased after treadmill exercises that increased the amount of PRiMA AChE(G4), but not ColQ AChE(A12) molecular forms. Carbon 26-27 acetylcholinesterase Rattus norvegicus 116-120 21232040-10 2011 The main form of AChE in brain, PRiMA AChE(G4), was apparently less sensitive because brain cholinesterase activity was almost three orders of magnitude more resistant to C-547 than that of the EDL. Carbon 18-19 acetylcholinesterase Rattus norvegicus 38-42 25195029-13 2014 Due to the low reduction in hydraulic conductivity, GAC-treated water quality was used to set pre-treatment targets for ASR injection of turbidity <0.6 NTU, membrane filtration index (MFI) < 2 s/L(2), biodegradable dissolved organic carbon (BDOC) < 0.2 mg/L, total nitrogen < 0.3 mg/L and residual chlorine > 0.2 mg/L. Carbon 239-245 glutaminase Homo sapiens 52-55 2885314-8 1987 The signals due to 2- and 4-13C were more sensitive to the formation of the inhibitor-DAO complexes than those of the other carbon atoms. Carbon 124-130 D-amino acid oxidase Homo sapiens 86-89 21454678-0 2011 Direct evidence for methyl group coordination by carbon-oxygen hydrogen bonds in the lysine methyltransferase SET7/9. Carbon 49-55 SET domain containing 7, histone lysine methyltransferase Homo sapiens 110-116 3820221-4 1987 Replacement of the C-1 carbon atom in compound 3 with a sulfur [dihydropyrrolo[2,1-b]thiazole-3,5(2H,6H)-dione (10)] abolished activity, and the introduction of methyl groups resulted in poorer biological profiles except when the substitution was made at the 7a position [dihydro-7a-methyl-1H-pyrrolizine-3,5(2H,6H)-dione (4)]. Carbon 23-29 heterogeneous nuclear ribonucleoprotein C Homo sapiens 19-22 21600518-11 2011 CONCLUSION: The strongest predictors for CIMT progression in anterior and posterior walls were lower baseline CIMT, increased TG, and elevated ratios, including TC/HDL-C, TG/HDL-C and Apo B/HDL-C. Carbon 167-169 CIMT Homo sapiens 41-45 25553002-1 2014 The title compound, C11H17BrN2O5, is a de-hydro-amino acid with a C=C bond between the alpha- and beta-C atoms. Carbon 20-21 colony stimulating factor 2 receptor subunit beta Homo sapiens 87-104 25553002-1 2014 The title compound, C11H17BrN2O5, is a de-hydro-amino acid with a C=C bond between the alpha- and beta-C atoms. Carbon 66-67 colony stimulating factor 2 receptor subunit beta Homo sapiens 87-104 25181331-0 2014 Synthesis and photocatalytic activities of CdS/TiO2 nanoparticles supported on carbon nanofibers for high efficient adsorption and simultaneous decomposition of organic dyes. Carbon 79-85 CDP-diacylglycerol synthase 1 Homo sapiens 43-46 25181331-1 2014 CdS/TiO2 NPs-decorated carbon nanofibers were prepared by a simple electrospinning method followed by the calcination under argon atmosphere. Carbon 23-29 CDP-diacylglycerol synthase 1 Homo sapiens 0-3 3816805-0 1987 High-resolution solid-state 13C-NMR study of carbons C-5 and C-12 of the chromophore of bovine rhodopsin. Carbon 45-52 rhodopsin Bos taurus 95-104 25181331-4 2014 Therefore, the enhanced photocatalytic performance for the introduced nanofibers might be attributed to the adsorption characteristic of carbon nanofiber and the known photocatalytic activities of the TiO2 and CdS photocatalysts. Carbon 137-143 CDP-diacylglycerol synthase 1 Homo sapiens 210-213 21532989-8 2011 However, mutation of specific amino acids of hANT4 improved yeast mitochondrial expression and supported growth of the AAC-deficient yeast on non-fermentable carbon sources. Carbon 158-164 solute carrier family 25 member 31 Homo sapiens 45-50 21336404-3 2011 The results showed that the optimal carbon chain lengths for the lipid amine and fatty acid to activate TLR4 were 10-11 and 12, respectively. Carbon 36-42 toll like receptor 4 Homo sapiens 104-108 25164482-5 2014 In addition, the CCl3 species was capable of binding covalently to the meso-carbon atom of the prosthetic group, leading to the suicidal destruction of P450 enzymes. Carbon 77-83 C-C motif chemokine ligand 3 Homo sapiens 18-22 3816805-3 1987 Spectra were obtained from lyophilized samples of bovine rhodopsin selectively 13C-labeled at position C-5 or C-12 of the retinyl moiety, and reconstituted in the fully saturated branched-chain phospholipid diphytanoyl glycerophosphocholine. Carbon 81-82 rhodopsin Bos taurus 57-66 3816805-5 1987 (1985) Biochemistry 24, 6955-6962], indicate that in bovine rhodopsin the C-6-C-7 single bond has the unperturbed cis conformation. Carbon 74-75 rhodopsin Bos taurus 60-69 3816805-5 1987 (1985) Biochemistry 24, 6955-6962], indicate that in bovine rhodopsin the C-6-C-7 single bond has the unperturbed cis conformation. Carbon 78-79 rhodopsin Bos taurus 60-69 24920060-5 2014 Complexes 1-Y and 1-Sc form adducts with CpH without cleaving the acidic C-H bond, 1-Ce cleaves the Cp-H bond, but 2 reacts to form the very rare H(+)-[C5H5](-)-H(+) motif. Carbon 0-1 carboxypeptidase E Homo sapiens 100-104 20573497-4 2011 We previously demonstrated that presenilin1 (PSEN1), a gene involved in amyloidogenesis, is modulated by DNA methylation in neuroblastoma cells and Alzheimer"s mice in an experimental model of nutritionally altered one-carbon metabolism. Carbon 219-225 presenilin 1 Mus musculus 32-43 20573497-4 2011 We previously demonstrated that presenilin1 (PSEN1), a gene involved in amyloidogenesis, is modulated by DNA methylation in neuroblastoma cells and Alzheimer"s mice in an experimental model of nutritionally altered one-carbon metabolism. Carbon 219-225 presenilin 1 Mus musculus 45-50 3816805-7 1987 The NMR parameters for bovine [12-13C]rhodopsin present evidence for the presence of a negative charge interacting with the retinyl moiety near C-12, in agreement with the model for the opsin shift presented by Honig and Nakanishi and coworkers [Kakitani et al. Carbon 36-37 rhodopsin Bos taurus 38-47 2957284-3 1987 The latter attacks the deoxyribose, especially at thymidylate residues, by abstracting a hydrogen atom from C-5" to generate a carbon-centered radical on the DNA. Carbon 127-133 complement C5 Homo sapiens 108-111 21254914-9 2011 There was an increase in the ratio of 2-hydroxyestrones (C-2) to 16alpha-hydroxyestrone (C-16), consistent with antiestrogenic activity that results in more of C-2 product compared with C-16. Carbon 89-90 complement C2 Homo sapiens 160-163 25140359-0 2014 Tip-enhanced Raman spectroscopic measurement of stress change in the local domain of epitaxial graphene on the carbon face of 4H-SiC(000-1). Carbon 111-117 TOR signaling pathway regulator Homo sapiens 0-3 25145958-1 2014 The electronically unsaturated dirhenium complex [Re2(CO)8(micro-AuPPh3)(micro-Ph)] (1) was obtained from the reaction of [Re2(CO)8{micro-eta(2)-C(H)=C(H)nBu}(micro-H)] with [Au(PPh3)Ph]. Carbon 54-55 protein phosphatase 4 catalytic subunit Homo sapiens 67-71 3021640-2 1986 In the monoclinic form, the radical arises by the loss of a hydrogen atom from the carbon atom C(2), whereas, in the orthorhombic form, it arises by addition of a hydrogen atom to the oxygen atom O(3). Carbon 83-89 complement C2 Homo sapiens 95-99 25099012-2 2014 Using a series of 14 different p-substituted phenyl C-DIMs, we show that several compounds including DIM-C-pPhOH directly interacted with the ligand binding domain of NR4A1. Carbon 52-53 nuclear receptor subfamily 4, group A, member 1 Mus musculus 167-172 21214219-3 2011 We report here the direct observation of organized binding of C1 components C1q and C1s-C1r-C1r-C1s on carbon nanotubes, an ubiquitous component in nanotechnology research. Carbon 103-109 complement C1q A chain Homo sapiens 76-79 21204551-7 2011 The integrated evaluation of the dissociation energies of the C-H bonds calculated both by semiempirical and DFT methods and the differential activation energies of the process estimated by a molecular modeling approach suggested that the observed selective oxidation at the C-4 carbon has a kinetic origin. Carbon 279-285 complement C4A (Rodgers blood group) Homo sapiens 275-278 25048470-0 2014 Multi-walled carbon nanotube inhibits CA1 glutamatergic synaptic transmission in rat"s hippocampal slices. Carbon 13-19 carbonic anhydrase 1 Rattus norvegicus 38-41 21232955-3 2011 Compound 1, characterized by the presence of a C-16/C-17, C-20/C-21 conjugated diene and a C-1/C-7 ester bridge formed in rings A and B, provided a novel structural skeleton for 3,4-secocycloartane triterpenoid derivatives. Carbon 0-1 cytokine like 1 Homo sapiens 52-56 3021640-4 1986 In the orthorhombic single crystal, we observed interaction of the unpaired electron, which is delocalized on the carbons C(3), C(4) and C(5) with one alpha-proton in position 4 and with four nonequivalent beta-protons connected with the carbon atoms C(2) and C(6). Carbon 114-120 complement C4A (Rodgers blood group) Homo sapiens 128-132 21232955-3 2011 Compound 1, characterized by the presence of a C-16/C-17, C-20/C-21 conjugated diene and a C-1/C-7 ester bridge formed in rings A and B, provided a novel structural skeleton for 3,4-secocycloartane triterpenoid derivatives. Carbon 47-48 cytokine like 1 Homo sapiens 52-56 3021640-4 1986 In the orthorhombic single crystal, we observed interaction of the unpaired electron, which is delocalized on the carbons C(3), C(4) and C(5) with one alpha-proton in position 4 and with four nonequivalent beta-protons connected with the carbon atoms C(2) and C(6). Carbon 114-120 complement C5 Homo sapiens 137-141 3021640-4 1986 In the orthorhombic single crystal, we observed interaction of the unpaired electron, which is delocalized on the carbons C(3), C(4) and C(5) with one alpha-proton in position 4 and with four nonequivalent beta-protons connected with the carbon atoms C(2) and C(6). Carbon 114-120 complement C2 Homo sapiens 251-255 16665079-2 1986 E(1) is capable of accumulating inorganic carbon (C(i)) internally as efficiently as the wild type (R(2)). Carbon 42-48 small nucleolar RNA, H/ACA box 73A Homo sapiens 0-4 21115279-1 2011 This paper reported the enzymatic deposition of Au nanoparticles (AuNPs) on the designed 3-mercapto-propionic acid/glucose oxidase/chitosan (MPA/GOD/Chit) modified glassy carbon electrode and its application in glucose detection. Carbon 171-177 chitinase 1 Homo sapiens 149-153 25064349-1 2014 Synthesis and functionalization strategies of the imidazo[1,2-b]pyrazole core were developed giving a rapid access to three series of novel imidazo[1,2-b]pyrazole type derivatives: C-2/C-6/C-7 trisubstituted, C-2/C-3/C-6 tri(hetero)arylated and C-2/C-3/C-6/C-7 tetrasubstituted imidazo[1,2-b]pyrazoles. Carbon 181-182 complement C2 Homo sapiens 209-212 25064349-1 2014 Synthesis and functionalization strategies of the imidazo[1,2-b]pyrazole core were developed giving a rapid access to three series of novel imidazo[1,2-b]pyrazole type derivatives: C-2/C-6/C-7 trisubstituted, C-2/C-3/C-6 tri(hetero)arylated and C-2/C-3/C-6/C-7 tetrasubstituted imidazo[1,2-b]pyrazoles. Carbon 181-182 complement C2 Homo sapiens 209-212 2944558-3 1986 The measurement of m/z 64 for SO2 in a CO2-scavenged discharge can be used to determine the amount of sulfur originally introduced into the interface; carbon is quantified as HCN (m/z 27) in a nitrogen-scavenged discharge. Carbon 151-157 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 175-178 24817445-4 2014 Additionally, quaternary stereogenic carbon center-containing indoloquinolizidines were prepared through NBS-mediated cyclization of one of the intermediates. Carbon 37-43 nibrin Homo sapiens 105-108 20730777-6 2011 Low vibrational frequencies of the alpha-carbon atoms of DHFR are determined from the time series models of a larger number of low indexed PCs, and it is found that number of modes in the lowest frequencies is reduced upon ligand binding. Carbon 41-47 dihydrofolate reductase Homo sapiens 57-61 21456242-2 2011 Bands at 1152 and 1322 cm(-1) were also similar to SERS of metal catecholates, and could be assigned to catechol ring vibration and carbon-oxygen stretches. Carbon 132-138 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 51-55 3782058-5 1986 Furthermore, although the carbon-13 NMR signals of sphingosine C-1, C-2, C-3, C-4, and C-5 showed significant chemical shift differences between D-erythro and L-threo-sphingosines of lysosphingolipids, it was concluded that the signal position of sphingosine C-3 was the most important for the determination of D-erythro and L-threo configuration in the long chain base moieties of lysosphingolipids. Carbon 26-32 heterogeneous nuclear ribonucleoprotein C Homo sapiens 63-66 21155555-4 2011 The most stable isomers of Co(1-2)C(2)H(-) clusters are linear with the C(2)H interacting with only one Co atom, while those of Co(3-5)C(2)H(-) cluster anions are quasi-planar structures with the carbon-carbon bonds bending slightly toward the Co(3-5) clusters. Carbon 196-202 complement C4A (Rodgers blood group) Homo sapiens 128-134 21155555-4 2011 The most stable isomers of Co(1-2)C(2)H(-) clusters are linear with the C(2)H interacting with only one Co atom, while those of Co(3-5)C(2)H(-) cluster anions are quasi-planar structures with the carbon-carbon bonds bending slightly toward the Co(3-5) clusters. Carbon 203-209 complement C2 Homo sapiens 27-33 21155555-4 2011 The most stable isomers of Co(1-2)C(2)H(-) clusters are linear with the C(2)H interacting with only one Co atom, while those of Co(3-5)C(2)H(-) cluster anions are quasi-planar structures with the carbon-carbon bonds bending slightly toward the Co(3-5) clusters. Carbon 203-209 complement C4A (Rodgers blood group) Homo sapiens 128-134 21155555-5 2011 The carbon-carbon bond of C(2)H is lengthened more in Co(3-5)C(2)H(-) clusters than in Co(1-2)C(2)H(-). Carbon 4-10 complement C4A (Rodgers blood group) Homo sapiens 54-60 21155555-5 2011 The carbon-carbon bond of C(2)H is lengthened more in Co(3-5)C(2)H(-) clusters than in Co(1-2)C(2)H(-). Carbon 4-10 complement C2 Homo sapiens 87-93 21155555-5 2011 The carbon-carbon bond of C(2)H is lengthened more in Co(3-5)C(2)H(-) clusters than in Co(1-2)C(2)H(-). Carbon 11-17 complement C4A (Rodgers blood group) Homo sapiens 54-60 21155555-5 2011 The carbon-carbon bond of C(2)H is lengthened more in Co(3-5)C(2)H(-) clusters than in Co(1-2)C(2)H(-). Carbon 11-17 complement C2 Homo sapiens 87-93 21155555-5 2011 The carbon-carbon bond of C(2)H is lengthened more in Co(3-5)C(2)H(-) clusters than in Co(1-2)C(2)H(-). Carbon 26-27 complement C4A (Rodgers blood group) Homo sapiens 54-60 21155555-5 2011 The carbon-carbon bond of C(2)H is lengthened more in Co(3-5)C(2)H(-) clusters than in Co(1-2)C(2)H(-). Carbon 26-27 complement C2 Homo sapiens 87-93 25115676-3 2014 Functionalized single-walled carbon nanotubes (SWNT) restored normal autophagy by reversing abnormal activation of mTOR signaling and deficits in lysosomal proteolysis, thereby facilitating elimination of autophagic substrates. Carbon 29-35 mechanistic target of rapamycin kinase Mus musculus 115-119 25180573-8 2014 In the hypothalamus, prenatal exposure to PolyI:C caused significant global DNA hypomethylation (t=2.44, P=0.019, PolyI:C mean 69.67%, saline mean 70.19%), especially in females, and significant hypomethylation of the promoter region of Mecp2, (t=3.32, P=0.002; PolyI:C mean 26.57%, saline mean 34.63%). Carbon 48-49 methyl CpG binding protein 2 Mus musculus 237-242 25092115-1 2014 We report on a one-step method for preparing nitrogen doped (N-doped) meso-/microporous hybrid carbon material (NCF) via the heat treatment of used cigarette filters under a nitrogen-containing atmosphere. Carbon 95-101 neutrophil cytosolic factor 4 Homo sapiens 112-115 25092115-4 2014 The NCF exhibited a better rate capability and higher specific capacitance (153.8 F g(-1)) compared to that of conventional activated carbon (125.0 F g(-1)) at 1 A g(-1). Carbon 134-140 neutrophil cytosolic factor 4 Homo sapiens 4-7 3782058-5 1986 Furthermore, although the carbon-13 NMR signals of sphingosine C-1, C-2, C-3, C-4, and C-5 showed significant chemical shift differences between D-erythro and L-threo-sphingosines of lysosphingolipids, it was concluded that the signal position of sphingosine C-3 was the most important for the determination of D-erythro and L-threo configuration in the long chain base moieties of lysosphingolipids. Carbon 26-32 complement C2 Homo sapiens 68-76 21522830-1 2011 The title compound, [Sn(2)(CH(3)O)(2)Cl(6)(C(3)H(7)NO)(2)], contains two hexa-coordinated Sn(IV) atoms symmetrically bridged by two deprotonated methanol ligands, with an inversion center in the middle of the planar Sn(2)O(2) ring. Carbon 27-28 hexosaminidase subunit alpha Homo sapiens 73-77 3782058-5 1986 Furthermore, although the carbon-13 NMR signals of sphingosine C-1, C-2, C-3, C-4, and C-5 showed significant chemical shift differences between D-erythro and L-threo-sphingosines of lysosphingolipids, it was concluded that the signal position of sphingosine C-3 was the most important for the determination of D-erythro and L-threo configuration in the long chain base moieties of lysosphingolipids. Carbon 26-32 complement C4A (Rodgers blood group) Homo sapiens 78-81 3782058-5 1986 Furthermore, although the carbon-13 NMR signals of sphingosine C-1, C-2, C-3, C-4, and C-5 showed significant chemical shift differences between D-erythro and L-threo-sphingosines of lysosphingolipids, it was concluded that the signal position of sphingosine C-3 was the most important for the determination of D-erythro and L-threo configuration in the long chain base moieties of lysosphingolipids. Carbon 26-32 complement C5 Homo sapiens 87-90 22114499-0 2011 DJ-1 as a potential biomarker for the development of biocompatible multiwalled carbon nanotubes. Carbon 79-85 Parkinsonism associated deglycase Homo sapiens 0-4 3537696-3 1986 Only when cells were starved for a carbon source for 2 h in 1 M sorbitol was eIF-2 alpha isolated in the nonphosphorylated state. Carbon 35-41 eukaryotic translation initiation factor 2A Oryctolagus cuniculus 77-88 21687714-0 2011 The Sea Peoples, from cuneiform tablets to carbon dating. Carbon 43-49 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 4-7 25184115-10 2014 Thus proline oxidation by proline dehydrogenase drives superoxide/H2O2 production, but it does so mainly or exclusively by providing anaplerotic carbon for other mitochondrial dehydrogenases and not by producing superoxide/H2O2 directly. Carbon 145-151 proline dehydrogenase 1 Homo sapiens 26-47 3515096-4 1986 Our first approach was the synthesis and biological evaluation of 2-aza-2,3-dihydrosqualene and its derivatives which, being protonated at physiological pH, would present some similarities to the C-2 carbon ion generated by the opening of the oxirane ring of SO. Carbon 200-206 complement C2 Rattus norvegicus 196-199 24875845-1 2014 Alterations in glial fibrillary acidic protein (GFAP) levels accompany the changes in the morphology and proliferation of astrocytes induced by colloidal solutes and films of carbon nanotubes (CNTs). Carbon 175-181 glial fibrillary acidic protein Mus musculus 48-52 25194438-1 2014 BACKGROUND: The serine hydroxymethyltransferase (SHMT1) is the key enzyme in the folate metabolic pathway to provide one-carbon unit that plays an important role in biosynthesis. Carbon 121-127 serine hydroxymethyltransferase 1 Homo sapiens 49-54 24769085-5 2014 The feedback-resistant DAHP synthase encoded by aroG was achieved by replacing the residue Pro150 of aroG with Leu as to increase net carbon flow down the common pathway. Carbon 134-140 AroG Escherichia coli 48-52 22105129-1 2011 The present work highlights the preparation of activated carbons (ACs) using spent coffee grounds, an agricultural residue, as carbon precursor and two different activating agents: water vapor (ACW) and K(2)CO(3) (ACK). Carbon 57-64 tyrosine kinase non receptor 2 Homo sapiens 214-217 22105129-1 2011 The present work highlights the preparation of activated carbons (ACs) using spent coffee grounds, an agricultural residue, as carbon precursor and two different activating agents: water vapor (ACW) and K(2)CO(3) (ACK). Carbon 57-63 tyrosine kinase non receptor 2 Homo sapiens 214-217 20961854-5 2010 Using (13)C-detected NMR experiments, we have mapped the residues within the intrinsically unstructured fragment of MLL that are required for binding to menin. Carbon 10-11 lysine methyltransferase 2A Homo sapiens 116-119 24769085-5 2014 The feedback-resistant DAHP synthase encoded by aroG was achieved by replacing the residue Pro150 of aroG with Leu as to increase net carbon flow down the common pathway. Carbon 134-140 AroG Escherichia coli 101-105 3915775-4 1985 The HAP2 locus encodes a 1.3-kilobase transcript which is present at extremely low levels and which is derepressed in cells grown in media containing nonfermentable carbon sources. Carbon 165-171 transcription activator HAP2 Saccharomyces cerevisiae S288C 4-8 24857488-1 2014 In this paper a novel sensing platform based on graphene oxide (GO), ionic liquid (IL) 1-ethyl-3-methylimidazolium tetrafluoroborate and Nafion for the immobilization of hemoglobin (Hb) was adopted with a carbon ionic liquid electrode (CILE) as the substrate electrode, which was denoted as Nafion/Hb-GO-IL/CILE. Carbon 205-211 interleukin 1 alpha Homo sapiens 69-88 20858221-6 2010 Mth1p was expressed in cells grown in a medium containing galactose, but was lost (possibly degraded) when cells were grown in medium containing glucose as the sole carbon source. Carbon 165-171 Mth1p Saccharomyces cerevisiae S288C 0-5 20858221-11 2010 These results implicate Mth1p as a novel regulator of Nhx1p that responds to specific extracellular carbon sources. Carbon 100-106 Mth1p Saccharomyces cerevisiae S288C 24-29 20685216-5 2010 Hydroxylations at C-6, C-10, C-11, C-15 positions and alpha,beta-unsaturation at C-1/C-2, C-4/C-5 showed potent inhibitory activities against these enzymes. Carbon 18-19 complement C2 Homo sapiens 85-88 2988021-1 1985 We showed previously that polyenoic fatty acids with double bonds at carbon 5,8,11 are good substrates for the 5-lipoxygenase and also can be converted to LTC and dihydroxy acids. Carbon 69-75 arachidonate 5-lipoxygenase Rattus norvegicus 111-125 20685216-5 2010 Hydroxylations at C-6, C-10, C-11, C-15 positions and alpha,beta-unsaturation at C-1/C-2, C-4/C-5 showed potent inhibitory activities against these enzymes. Carbon 18-19 complement C4A (Rodgers blood group) Homo sapiens 90-97 24805883-2 2014 The CCR4-NOT complex, containing the two key components carbon catabolite repressor 4 (CCR4) and CCR4-associated factor 1 (CAF1), is a major player in deadenylation. Carbon 56-62 CCR4-NOT core DEDD family RNase subunit POP2 Saccharomyces cerevisiae S288C 123-127 21028817-4 2010 Binding of CO to l-Trp-bound IDO causes a significant change in the electronic and RR spectra of the heme, indicating that the pi* orbitals of the carbon atom of CO interact with pi orbitals of Fe and the porphyrin. Carbon 147-153 indoleamine 2,3-dioxygenase 1 Homo sapiens 29-32 3891963-5 1985 GF-1 enhanced the antigen specific antibody response and carbon clearance activity, whereas GF-1 did not show polyclonal B cell activation and mitogenic activities, and the effect on delayed type hypersensitivity. Carbon 57-63 gonadal fat pad weight 1 Mus musculus 0-4 20942445-0 2010 The reactivity of phosphagermaallene Tip(t-Bu)Ge=C=PMes* with doubly and triply bonded nitrogen compounds. Carbon 49-50 TOR signaling pathway regulator Homo sapiens 37-40 26270493-2 2014 In the most stable 2D planar AlC network, every carbon atom is tetracoordinated. Carbon 48-54 allantoicase Homo sapiens 29-32 24525015-1 2014 Herein we describe improved electron transfer properties and catalytic activity of nickel oxide nanoparticles (NiONPs) via the electrochemical deposition on DNA modified glassy carbon electrode (DNA/GCE) surface. Carbon 177-183 aminomethyltransferase Homo sapiens 199-202 21053976-9 2010 Furthermore, the compound 2 bulk-modified carbon-paste electrode (2-CPE) displays good electrocatalytic activity toward the reduction of nitrite. Carbon 42-48 carboxypeptidase E Homo sapiens 68-71 2983185-5 1985 Calculated electron and spin densities indicate that the radical formed by H abstraction from the phenol oxygen does not remain localized on the oxygen, but is primarily a semiquinone aryl radical with significant unpaired spin density on the ring carbon atoms, particularly on C-3 and C-5. Carbon 248-254 complement C5 Homo sapiens 286-289 21039575-3 2010 This study synthesized a composite photocatalyst by loading titanium dioxide onto activated carbon fiber (TiO(2)/ACF). Carbon 92-98 ACF Homo sapiens 113-116 24971065-0 2014 Role of H-Ras/ERK signaling in carbon nanotube-induced neoplastic-like transformation of human mesothelial cells. Carbon 31-37 HRas proto-oncogene, GTPase Homo sapiens 8-13 3908221-3 1985 The intracellular concentration of GAL80 mRNA increased by changing the carbon source to galactose by a factor of more than 5, in contrast to a GAL4 mRNA concentration which is essentially unaffected by galactose [Laughon and Gesteland, Proc. Carbon 72-78 transcription regulator GAL80 Saccharomyces cerevisiae S288C 35-40 20717564-2 2010 A ~30 nm carbon nanoparticle acts as a Raman reporter and is placed on different locations on a single semishell or nanobowl by e-beam induced deposition method, and remarkably different SERS intensities are observed. Carbon 9-15 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 187-191 24738840-3 2014 We present here a new material, termed nitrogen-rich carbon aerogels (NRC aerogels,) with highly porous structure and nitrogen-rich surfaces, exhibiting highly efficient separation of specific substances such as oils and organic pollutants. Carbon 53-59 nuclear receptor coactivator 6 Homo sapiens 70-73 6547601-0 1984 Production of C-24- and C-23-oxidized metabolites of 1,25-dihydroxycholecalciferol by cultured kidney cells (LLC PK1) and their presence in kidney in vivo. Carbon 14-15 pyruvate kinase L/R Rattus norvegicus 113-116 24594387-9 2014 These results suggest that Mmp3 is a possible mediator of polyI:C-ACM-induced neurodevelopmental impairment. Carbon 64-65 matrix metallopeptidase 3 Mus musculus 27-31 20694229-0 2010 Electrogenerated chemiluminescence from CdS hollow spheres composited with carbon nanofiber and its sensing application. Carbon 75-81 CDP-diacylglycerol synthase 1 Homo sapiens 40-43 6087242-3 1984 The maximum yields of HCN and H2CO from CH4, CO, and CO2 as carbon sources are about 4 X 10(-8) moles cal-1. Carbon 60-66 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 22-25 20801379-1 2010 The direct amperometric determination of tert-butylhydroquinone (TBHQ) in biodiesel at an unmodified glassy carbon electrode is reported. Carbon 108-114 telomerase reverse transcriptase Homo sapiens 41-45 24304103-8 2014 Using linear regression, the best estimation of MPA AUC was provided by a model including C(30), C(2) and C(4): AUC = 8 5 + 0 77 C(30) + 4 0 C(2) + 1 7 C(4) (P < 0 0001). Carbon 54-55 complement C2 Homo sapiens 97-101 24304103-8 2014 Using linear regression, the best estimation of MPA AUC was provided by a model including C(30), C(2) and C(4): AUC = 8 5 + 0 77 C(30) + 4 0 C(2) + 1 7 C(4) (P < 0 0001). Carbon 54-55 complement C4A (Rodgers blood group) Homo sapiens 106-110 24304103-8 2014 Using linear regression, the best estimation of MPA AUC was provided by a model including C(30), C(2) and C(4): AUC = 8 5 + 0 77 C(30) + 4 0 C(2) + 1 7 C(4) (P < 0 0001). Carbon 54-55 complement C2 Homo sapiens 141-145 24584631-3 2014 A CYP1A2-catalyzed carbon-carbon bond cleavage reaction is required for conversion of the prodrug nabumetone to its active form, 6-methoxy-2-naphthylacetic acid (6-MNA). Carbon 19-25 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 2-8 24584631-3 2014 A CYP1A2-catalyzed carbon-carbon bond cleavage reaction is required for conversion of the prodrug nabumetone to its active form, 6-methoxy-2-naphthylacetic acid (6-MNA). Carbon 26-32 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 2-8 24584631-5 2014 With the help of authentic synthetic standards, we report here that the reaction involves 3-hydroxylation, carbon-carbon cleavage to the aldehyde, and oxidation of the aldehyde to the acid, all catalyzed by CYP1A2 or, less effectively, by other P450 enzymes. Carbon 107-113 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 207-213 24584631-5 2014 With the help of authentic synthetic standards, we report here that the reaction involves 3-hydroxylation, carbon-carbon cleavage to the aldehyde, and oxidation of the aldehyde to the acid, all catalyzed by CYP1A2 or, less effectively, by other P450 enzymes. Carbon 114-120 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 207-213 20798055-3 2010 Here we examine the impact of five geoengineering approaches on sea level; SO(2) aerosol injection into the stratosphere, mirrors in space, afforestation, biochar, and bioenergy with carbon sequestration. Carbon 183-189 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 64-67 20798055-6 2010 The least risky and most desirable way of limiting sea-level rise is bioenergy with carbon sequestration. Carbon 84-90 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 51-54 6217836-3 1982 At pH 7.0 and 61 degrees C, the incorporation of 18O from solvent H2(18)O onto the C-1 carbon atom of the diastereomeric alpha- and beta-pyranose sugars was followed by 13C NMR spectroscopy in a continuous assay mode. Carbon 87-93 heterogeneous nuclear ribonucleoprotein C Homo sapiens 83-86 20799741-2 2010 Complexes [{Au(C,N-C(6)H(4)CH(2)NMe(2)-2)}{Ag(X)(PPh(3))}{S(2)C=C{C(O)Me}(2)}] [X = OClO(3) (3), ONO(2) (4)] have been obtained by reaction of 1 with PPh(3) and AgClO(4) or AgNO(3), respectively (1:1:1). Carbon 0-1 protein phosphatase 4 catalytic subunit Homo sapiens 49-55 20799741-2 2010 Complexes [{Au(C,N-C(6)H(4)CH(2)NMe(2)-2)}{Ag(X)(PPh(3))}{S(2)C=C{C(O)Me}(2)}] [X = OClO(3) (3), ONO(2) (4)] have been obtained by reaction of 1 with PPh(3) and AgClO(4) or AgNO(3), respectively (1:1:1). Carbon 0-1 protein phosphatase 4 catalytic subunit Homo sapiens 150-156 20466535-1 2010 In this study, a novel acetylcholinesterase (AChE) biosensor was developed based on dual-layer membranes (chitosan membrane and prussian blue membrane) modifying glassy carbon electrode (GCE). Carbon 169-175 guanylate cyclase 2E, pseudogene Homo sapiens 187-190 24525332-4 2014 By inactivation of pyruvate decarboxylases (PDCs) followed by overexpression of MTH1 and adaptive evolution, the resultant yeast grew on glucose as the sole carbon source with ethanol production completely eliminated. Carbon 157-163 Mth1p Saccharomyces cerevisiae S288C 80-84 6119109-11 1981 The 13C incorporation data indicate that carbons 1, 2, 3, and 4, but not 5, of glutamate serve as the four-carbon donor for the carboxamide carbon, C-5, C-4, and C-3, respectively, of the pyrazole ring of pyrazofurin. Carbon 41-48 complement C5 Homo sapiens 148-151 24569668-1 2014 Single-stranded DNA (ss-DNA) oligomers (dA20, d[(C3TA2)3C3] or dT20) are able to disperse single-walled carbon nanotubes (SWNTs) in water at pH 7 through non-covalent wrapping on the nanotube surface. Carbon 104-110 thioredoxin peroxidase 1 Drosophila melanogaster 63-67 20489167-5 2010 In Npc1(-/-) hepatocytes, the incorporation of [3H]oleic acid and [3H]acetate into TG was decreased, but shunting of oleic acid- or acetate-derived [3H]carbons into cholesterol was increased. Carbon 152-159 NPC intracellular cholesterol transporter 1 Homo sapiens 3-7 20472730-7 2010 During fermentative production of recombinant enzymes in methanol medium, 1 ml of P. pastoris culture supernatant was found to contain approximately 3 ng of Sub2, while the enzyme was not detected during growth in a medium containing glycerol as a carbon source. Carbon 248-254 ATP-dependent RNA helicase SUB2 Saccharomyces cerevisiae S288C 157-161 20482580-1 2010 Nitrogen (N) effects on ecosystem carbon (C) budgets are critical to understand as C sequestration is considered as a mechanism to offset anthropogenic CO(2) emissions. Carbon 34-40 steroid sulfatase Homo sapiens 80-84 24402456-2 2014 ITK is a collection of C++ classes that poses the challenge of a steep learning curve should the user not have appropriate C++ programming experience. Carbon 23-26 IL2 inducible T cell kinase Homo sapiens 0-3 24402456-2 2014 ITK is a collection of C++ classes that poses the challenge of a steep learning curve should the user not have appropriate C++ programming experience. Carbon 123-126 IL2 inducible T cell kinase Homo sapiens 0-3 6119109-11 1981 The 13C incorporation data indicate that carbons 1, 2, 3, and 4, but not 5, of glutamate serve as the four-carbon donor for the carboxamide carbon, C-5, C-4, and C-3, respectively, of the pyrazole ring of pyrazofurin. Carbon 41-48 complement C4A (Rodgers blood group) Homo sapiens 153-156 6119109-11 1981 The 13C incorporation data indicate that carbons 1, 2, 3, and 4, but not 5, of glutamate serve as the four-carbon donor for the carboxamide carbon, C-5, C-4, and C-3, respectively, of the pyrazole ring of pyrazofurin. Carbon 41-47 complement C5 Homo sapiens 148-151 20685443-2 2010 Carbon paste (CPE) and glassy carbon (GCE) electrodes were successfully used as sensors for these drugs in Briton-Robinson (B-R) as buffer solution. Carbon 30-36 aminomethyltransferase Homo sapiens 38-41 6119109-11 1981 The 13C incorporation data indicate that carbons 1, 2, 3, and 4, but not 5, of glutamate serve as the four-carbon donor for the carboxamide carbon, C-5, C-4, and C-3, respectively, of the pyrazole ring of pyrazofurin. Carbon 41-47 complement C4A (Rodgers blood group) Homo sapiens 153-156 20479116-5 2010 Polyinosine-polycytidylic acid (poly I:C)-activated CD141+ DCs have a superior capacity to cross-present soluble protein antigen (Ag) to CD8+ cytotoxic T lymphocytes than poly I:C-activated CD1c+ DCs. Carbon 39-40 thrombomodulin Homo sapiens 52-57 6119109-11 1981 The 13C incorporation data indicate that carbons 1, 2, 3, and 4, but not 5, of glutamate serve as the four-carbon donor for the carboxamide carbon, C-5, C-4, and C-3, respectively, of the pyrazole ring of pyrazofurin. Carbon 107-113 complement C5 Homo sapiens 148-151 6119109-11 1981 The 13C incorporation data indicate that carbons 1, 2, 3, and 4, but not 5, of glutamate serve as the four-carbon donor for the carboxamide carbon, C-5, C-4, and C-3, respectively, of the pyrazole ring of pyrazofurin. Carbon 107-113 complement C4A (Rodgers blood group) Homo sapiens 153-156 6271696-5 1981 The first reaction, which occurs between the hydrogens of the C-2 carbon of the radicals and those of the methyl groups of the neighbouring molecules, can be followed at room temperature. Carbon 66-72 complement C2 Homo sapiens 62-65 20489023-4 2010 Notably, the cell cycle phosphatase Cdc14 associated with multiple kinases that revealed roles for Cdc14 in mitogen-activated protein kinase signaling, the DNA damage response, and metabolism, whereas interactions of the target of rapamycin complex 1 (TORC1) uncovered new effector kinases in nitrogen and carbon metabolism. Carbon 306-312 phosphoprotein phosphatase CDC14 Saccharomyces cerevisiae S288C 36-41 20298872-1 2010 The chemo-electrical properties of chitosan-carbon nanotubes (Chit-CNT) Conductive bio-Polymer nano-Composites (CPC) transducers processed by spray layer-by-layer (LbL) technique have been investigated. Carbon 44-50 chitinase 1 Homo sapiens 62-66 24176972-3 2014 Multiwalled carbon nanotubes/ionic liquid/chitosan (MWCNTs/IL/CHIT) nanocomposite was applied as the interface for covalent attachment of 3"-amine-terminated capture probe (3"-NH2-(CH2)6-TCTCTTGGACCC-5"). Carbon 12-18 chitinase 1 Homo sapiens 62-66 24512991-9 2014 Using carbon nanotube-based transistor, we here characterized that Mel-S interacted with small unilamellar liposomes more strongly than Mel-N. Carbon 6-12 macrolide efflux protein Escherichia coli 67-70 6271696-6 1981 The three other reactions could be conveniently monitored in gamma-irradiated polycrystalline alanine at 110 degrees C. The first of the other three reactions takes place between the methyl hydrogens of the radicals and the C-2 hydrogens of nearby molecules, while the remaining processes involve exchange between the hydrogen atoms of the amino group and those on the C-2 and C-3 carbon atoms of the deamination radical. Carbon 381-387 complement C2 Homo sapiens 224-227 20337491-2 2010 The transformation is carried out by a sequence of denitrogenative formation of iminyl copper species from alpha-azidocarbonyl compounds and their C-C bond cleavage, where molecular oxygen (1 atm) is a prerequisite to achieve the catalytic process and one of the oxygen atoms of O(2) was found to be incorporated into the beta-carbon fragment as a carboxylic acid. Carbon 118-124 ATM serine/threonine kinase Homo sapiens 192-195 6268741-1 1981 The ribonucleoprotein (RNP) of avian infectious bronchitis virus (IBV) was examined by electron microscopy after shadowing with carbon/platinum. Carbon 128-134 RNA binding region (RNP1, RRM) containing 3 Homo sapiens 23-26 19783375-0 2010 Detection of local, regional, and distant recurrence in patients with psa relapse after external-beam radiotherapy using (11)C-choline positron emission tomography. Carbon 125-126 kallikrein related peptidase 3 Homo sapiens 70-73 24269798-4 2014 In the present study, granular activated carbon was evaluated for concentration of MS2 from artificial seawater, and different parameters of the seawater were also compared. Carbon 41-47 MS2 Homo sapiens 83-86 24269798-6 2014 One gram of granular activated carbon was able to extract 6-log plaque forming units (PFU) of MS2 from 500ml seawater at 37 C. This study demonstrated that granular activated carbon can concentrate an enteric virus indicator from shellfish growing seawater effectively. Carbon 31-37 MS2 Homo sapiens 94-97 24269798-6 2014 One gram of granular activated carbon was able to extract 6-log plaque forming units (PFU) of MS2 from 500ml seawater at 37 C. This study demonstrated that granular activated carbon can concentrate an enteric virus indicator from shellfish growing seawater effectively. Carbon 175-181 MS2 Homo sapiens 94-97 6272728-7 1981 When assayed in both intact and detergent-disrupted microsomes, glucose 6-phosphatase inactivation was dependent on the number of carbon atoms in the alkyl side chain of the N-alkylmaleimides; this dependence was much more marked in disrupted microsomes. Carbon 130-136 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 64-85 24563201-7 2014 Like other atg mutants, ATG11-deficient plants senesce prematurely and are hypersensitive to nitrogen and fixed-carbon limitations. Carbon 112-118 meiotically up-regulated protein Arabidopsis thaliana 24-29 20390952-2 2010 For the herbicide 2,4-D [2,4-dichlorophenoxyacetic acid], we found that its organic carbon-normalized sorption coefficient, Koc, varied by four-fold, from 76 to 315 L kg(-1), in the Ap-horizon along a slope transect in an undulating agricultural field in Manitoba, Canada. Carbon 84-90 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 124-127 20336010-4 2010 In addition an unprecedented reactivity of DCP as a very reactive heterocyclic electrophile at the C-4 carbon was also evidenced: by changing the experimental conditions, cyanopyrrolyl- and cyanoindolyl-pyridazines were obtained through reactions of pyrrole and indole systems as carbon nucleophiles in formal SNAr2 processes where a CN group of DCP acts as leaving group. Carbon 103-109 complement C4A (Rodgers blood group) Homo sapiens 99-102 7213686-2 1981 13C spin-lattice relaxation times, nuclear Overhauser effects and spin-spin relaxation times have been measured for the C-4 carbon of cholesterol in phosphatidylcholine bilayers as a function of cholesterol content and temperature. Carbon 124-130 complement C4A (Rodgers blood group) Homo sapiens 120-123 19931644-3 2010 The mRNA levels of Vtg1 in EE2 (10 ng/L) and EE2+NP (10 ng/L and 25 microg/L, respectively) groups were induced more than 10(4) times both in 21 degrees C-12L and 30 degrees C-14L groups, but only 369+/-23 and 178+/-59-fold induced in 12 degrees C-10L group compared to the control, respectively. Carbon 153-154 vitellogenin 1 Danio rerio 19-23 19931644-3 2010 The mRNA levels of Vtg1 in EE2 (10 ng/L) and EE2+NP (10 ng/L and 25 microg/L, respectively) groups were induced more than 10(4) times both in 21 degrees C-12L and 30 degrees C-14L groups, but only 369+/-23 and 178+/-59-fold induced in 12 degrees C-10L group compared to the control, respectively. Carbon 174-175 vitellogenin 1 Danio rerio 19-23 19931644-3 2010 The mRNA levels of Vtg1 in EE2 (10 ng/L) and EE2+NP (10 ng/L and 25 microg/L, respectively) groups were induced more than 10(4) times both in 21 degrees C-12L and 30 degrees C-14L groups, but only 369+/-23 and 178+/-59-fold induced in 12 degrees C-10L group compared to the control, respectively. Carbon 174-175 vitellogenin 1 Danio rerio 19-23 24328337-2 2014 By linking the ortho-carbons of the aromatics positioned at C-4 and C-5, a fused framework is generated, removing the distortion from planarity and enhancing the influence of the substituents on the redox properties. Carbon 21-28 complement C4A (Rodgers blood group) Homo sapiens 60-63 24328337-2 2014 By linking the ortho-carbons of the aromatics positioned at C-4 and C-5, a fused framework is generated, removing the distortion from planarity and enhancing the influence of the substituents on the redox properties. Carbon 21-28 complement C5 Homo sapiens 68-71 7035837-5 1981 This agreed with observations that hexokinase activities were like wild-type during growth on non-fermentable carbon sources in hex2 mutants. Carbon 110-116 hexokinase Saccharomyces cerevisiae S288C 35-45 24660171-5 2014 An enzymatic assay showed that ScoT thioesterase can hydrolyse a 12-carbon acyl chain but the activity is too low to play a role in product release from the polyketide synthase. Carbon 68-74 3-oxoacid CoA-transferase 1 Homo sapiens 31-35 19942425-1 2010 In this work, the magnetic core-shell Fe(3)O(4)@Au nanoparticles attached to the surface of a magnetic glassy carbon electrode (MGCE) were applied to the immobilization/adsorption of myoglobin (Mb) for fabricating Mb/Fe(3)O(4)@Au biofilm. Carbon 110-116 myoglobin Homo sapiens 183-192 20052974-2 2010 The key step is a stereoselective TiCl(4)-mediated homochiral sulfoxide-directed allylation of ketal (SS)-3 to efficiently generate the challenging C-2 stereogenic carbon of chroman (SS,S)-2 with the correct absolute configuration. Carbon 164-170 complement C2 Homo sapiens 148-151 7420350-3 1980 (b) Two groups of THC-type cannabinoids which differ only in that the chemical groupings in one of them at C-1, C-2 are situated at C-1, C-6 in the other (but retain their stereochemistry) have almost equivalent psychotropic activity. Carbon 20-21 complement C2 Macaca mulatta 112-115 19948847-1 2010 Sulfidic, anoxic sediments of the moderately hypersaline Salton Sea contain gradients in salinity and carbon that potentially structure the sedimentary microbial community. Carbon 102-108 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 64-67 24344357-3 2014 Here we report that intravenous injections of multi-walled carbon nanotubes into p53 (a well-known cancer-susceptible gene) heterozygous pregnant mice can induce p53- dependent responses in fetal development. Carbon 59-65 transformation related protein 53, pseudogene Mus musculus 81-84 24344357-3 2014 Here we report that intravenous injections of multi-walled carbon nanotubes into p53 (a well-known cancer-susceptible gene) heterozygous pregnant mice can induce p53- dependent responses in fetal development. Carbon 59-65 transformation related protein 53, pseudogene Mus musculus 162-165 24344357-5 2014 A molecular mechanism study found that multi-walled carbon nanotubes directly triggered p53-dependent apoptosis and cell cycle arrest in response to DNA damage. Carbon 52-58 transformation related protein 53, pseudogene Mus musculus 88-91 16345461-8 1979 The existence of an intermediate depth zone of active microbial growth may be an important site for nutrient regeneration and may serve as a source of reduced carbon for mesopelagic and deep sea environments. Carbon 159-165 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 191-194 24257509-15 2014 We found significant SNP-by-pollutant interactions for rs7813, rs910925, and rs1062923 in GEMIN4 and black carbon and PM2.5 for miR-1, -126, -146a, -222, and -9, and for rs1640299 in DGCR8 and SO4 for miR-1 and -135a. Carbon 107-113 fibronectin type III and SPRY domain containing 1 Homo sapiens 128-133 24257509-15 2014 We found significant SNP-by-pollutant interactions for rs7813, rs910925, and rs1062923 in GEMIN4 and black carbon and PM2.5 for miR-1, -126, -146a, -222, and -9, and for rs1640299 in DGCR8 and SO4 for miR-1 and -135a. Carbon 107-113 fibronectin type III and SPRY domain containing 1 Homo sapiens 201-206 20672136-0 2010 Stable Field Emitters for a Miniature X-ray Tube Using Carbon Nanotube Drop Drying on a Flat Metal Tip. Carbon 55-61 TOR signaling pathway regulator Homo sapiens 99-102 20082776-1 2010 A phosphate-selective electrode based on surfactant-modified zeolite (SMZ) particles into carbon-paste has been proposed (SMZ-CPE). Carbon 90-96 carboxypeptidase E Homo sapiens 126-129 315415-4 1979 Urushiol is a mixture of alkylcatechols composed of a catechol ring coupled to mono-, di-, or tri-unsaturated C-15 or C-17 carbon side chains. Carbon 123-129 cytokine like 1 Homo sapiens 118-122 19748732-9 2010 However, among carbon containing functional groups, carbonyl carbon showed strong positive correlation with sorption of TNT (r=0.991) and 2,4-DNT (r=0.967) while O-alkyl carbon showed negative correlation (r=0.832 for TNT and r=0.828 for 2,4-DNT). Carbon 15-21 5', 3'-nucleotidase, cytosolic Homo sapiens 142-145 31773048-8 2014 We found that N- and C-terminal fragments, encoding multiple motifs including sequences involved in binding integrins and CD44, a domain know to promote adhesion contribute to OPN"s ability to increase HIV replication. Carbon 21-22 secreted phosphoprotein 1 Homo sapiens 176-179 23824663-2 2014 Proline-fueled mitochondrial metabolism involves the oxidative conversion of L-Proline to L-Glutamate in two enzymatic steps by means of Put1p and Put2p that help Saccharomyces cerevisiae to respond to changes in the nutritional environment by initiating the breakdown of L-Proline as a source for nitrogen, carbon, and energy. Carbon 308-314 1-pyrroline-5-carboxylate dehydrogenase Saccharomyces cerevisiae S288C 147-152 19748732-9 2010 However, among carbon containing functional groups, carbonyl carbon showed strong positive correlation with sorption of TNT (r=0.991) and 2,4-DNT (r=0.967) while O-alkyl carbon showed negative correlation (r=0.832 for TNT and r=0.828 for 2,4-DNT). Carbon 15-21 5', 3'-nucleotidase, cytosolic Homo sapiens 242-245 19847991-3 1979 The relation between log Vg and carbon number of the alkanol is nonlinear at C4 and below with negative deviations around 10% for C2 and C3 and a positive deviation of 25% for C1. Carbon 32-38 complement C2 Homo sapiens 130-139 19748732-9 2010 However, among carbon containing functional groups, carbonyl carbon showed strong positive correlation with sorption of TNT (r=0.991) and 2,4-DNT (r=0.967) while O-alkyl carbon showed negative correlation (r=0.832 for TNT and r=0.828 for 2,4-DNT). Carbon 52-58 5', 3'-nucleotidase, cytosolic Homo sapiens 142-145 19748732-9 2010 However, among carbon containing functional groups, carbonyl carbon showed strong positive correlation with sorption of TNT (r=0.991) and 2,4-DNT (r=0.967) while O-alkyl carbon showed negative correlation (r=0.832 for TNT and r=0.828 for 2,4-DNT). Carbon 52-58 5', 3'-nucleotidase, cytosolic Homo sapiens 242-245 20024364-1 2010 A facile synthesis of dibenzopyrroloazepinones via an electrophilic cyclisation of a biphenyl-acyliminium ion is described; an unusual 1,2-phenyl shift occurs when the C-1" carbon is the more nucleophilic than the C-2" carbon. Carbon 173-179 heterogeneous nuclear ribonucleoprotein C Homo sapiens 168-171 20024364-1 2010 A facile synthesis of dibenzopyrroloazepinones via an electrophilic cyclisation of a biphenyl-acyliminium ion is described; an unusual 1,2-phenyl shift occurs when the C-1" carbon is the more nucleophilic than the C-2" carbon. Carbon 173-179 complement C2 Homo sapiens 214-217 20024364-1 2010 A facile synthesis of dibenzopyrroloazepinones via an electrophilic cyclisation of a biphenyl-acyliminium ion is described; an unusual 1,2-phenyl shift occurs when the C-1" carbon is the more nucleophilic than the C-2" carbon. Carbon 219-225 heterogeneous nuclear ribonucleoprotein C Homo sapiens 168-171 20024364-1 2010 A facile synthesis of dibenzopyrroloazepinones via an electrophilic cyclisation of a biphenyl-acyliminium ion is described; an unusual 1,2-phenyl shift occurs when the C-1" carbon is the more nucleophilic than the C-2" carbon. Carbon 219-225 complement C2 Homo sapiens 214-217 23839951-0 2013 Functionalization of carbon nanoparticles modulates inflammatory cell recruitment and NLRP3 inflammasome activation. Carbon 21-27 NLR family, pyrin domain containing 3 Mus musculus 86-91 373758-0 1979 Distribution of hexokinase isoenzymes depending on a carbon source in Saccharomyces cerevisiae. Carbon 53-59 hexokinase Saccharomyces cerevisiae S288C 16-26 24239015-3 2013 Pharmacological characterization of the bis(bibenzyl) derivatives and 2-phenoxyphenol fragment 25, previously proposed as the minimum structure of riccardin C 1 for anti-MRSA activity, indicated that they have different action mechanisms: the bis(bibenzyl)s are bactericidal, while 25 is bacteriostatic, showing only weak bactericidal activity. Carbon 157-158 solute carrier family 9 member A6 Homo sapiens 170-174 20042217-0 2010 Aerobic biodegradation of cis-1,2-dichloroethene as sole carbon source: Stable carbon isotope fractionation and growth characteristics. Carbon 57-63 cytokine inducible SH2 containing protein Homo sapiens 26-31 20042217-0 2010 Aerobic biodegradation of cis-1,2-dichloroethene as sole carbon source: Stable carbon isotope fractionation and growth characteristics. Carbon 79-85 cytokine inducible SH2 containing protein Homo sapiens 26-31 752132-6 1978 The carbonium ions i-C3H7+ and t-C4H9+ condense also with HCN to yield protonated isocyanides. Carbon 4-13 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 58-61 20459380-1 2010 Ornithine transcarbamylase (OTC; EC 2.1.3.3) is a one-carbon-unit transferring enzyme that synthesizes citrulline using ornithine and carbamoylphosphate as substrates. Carbon 54-60 ornithine transcarbamylase Homo sapiens 0-26 20459380-1 2010 Ornithine transcarbamylase (OTC; EC 2.1.3.3) is a one-carbon-unit transferring enzyme that synthesizes citrulline using ornithine and carbamoylphosphate as substrates. Carbon 54-60 ornithine transcarbamylase Homo sapiens 28-31 23651442-2 2013 The scattering dynamics were found to be indirect (complex forming reaction) and the reaction proceeded through the barrier-less formation of a van-der-Waals complex ((11)BOC3H4) followed by isomerization via the addition of (11)BO(X(2)Sigma(+)) to the C1 and/or C2 carbon atom of methylacetylene through submerged barriers. Carbon 266-272 complement C2 Homo sapiens 253-265 24187982-8 2013 The enamido complex 9 reacts via beta-carbon methylation to give the primary imino complex cis-[Re(PNP(tBu)-HN CC(Me)Ph)(CO)2]OTf 11. Carbon 38-44 POU class 2 homeobox 3 Homo sapiens 126-132 210807-12 1978 Since the centre of the domain on the cytochrome c surface, which is involved in the binding to cytochrome c oxidase, is found at the beta-carbon of the Phe 82 in horse cytochrome c (Ferguson-Miller, S., Brautigan, D.L. Carbon 139-145 cytochrome c, somatic Equus caballus 38-50 24145444-3 2013 Elucidation of the processes that trap Na and produce large carbon molecules should yield insight into carbon stardust enrichment and formation. Carbon 60-66 protein associated with LIN7 1, MAGUK p55 family member Homo sapiens 110-118 24145444-3 2013 Elucidation of the processes that trap Na and produce large carbon molecules should yield insight into carbon stardust enrichment and formation. Carbon 103-109 protein associated with LIN7 1, MAGUK p55 family member Homo sapiens 110-118 19707223-2 2010 Cytoplasmic serine hydroxymethyltransferase (cSHMT) affects the flow of one-carbon units through the folate metabolic network, but there is little research on a role for genetic variation in cSHMT in determining breast cancer risk. Carbon 76-82 serine hydroxymethyltransferase 1 Homo sapiens 0-43 19707223-2 2010 Cytoplasmic serine hydroxymethyltransferase (cSHMT) affects the flow of one-carbon units through the folate metabolic network, but there is little research on a role for genetic variation in cSHMT in determining breast cancer risk. Carbon 76-82 serine hydroxymethyltransferase 1 Homo sapiens 45-50 210807-12 1978 Since the centre of the domain on the cytochrome c surface, which is involved in the binding to cytochrome c oxidase, is found at the beta-carbon of the Phe 82 in horse cytochrome c (Ferguson-Miller, S., Brautigan, D.L. Carbon 139-145 cytochrome c, somatic Equus caballus 96-108 32688720-7 2010 These data suggest that the induction of extracellular invertase Lin6 by stress-related stimuli requires LpMPK2 and LpMPK3, and thus demonstrate that MAPK signalling might be involved in the regulation of primary carbon metabolism in general and sink metabolism in particular. Carbon 213-219 acid invertase Solanum lycopersicum 65-69 210807-12 1978 Since the centre of the domain on the cytochrome c surface, which is involved in the binding to cytochrome c oxidase, is found at the beta-carbon of the Phe 82 in horse cytochrome c (Ferguson-Miller, S., Brautigan, D.L. Carbon 139-145 cytochrome c, somatic Equus caballus 96-108 667283-1 1978 Frog virus 3 (FV 3) inoculated intravenously into mice damages sinusoidal cells and produces a decrease in the carbon uptake capacity of the liver. Carbon 111-117 Friend virus susceptibility 3 Mus musculus 14-18 20198884-6 2010 The STAT5A/AvaI allele frequencies were as follows: C--88.31% and T--11.69%, whereas the genotype frequencies were 76.6% for CC and 23.4% for CT. Carbon 52-53 signal transducer and activator of transcription 5A Bos taurus 4-10 24180234-8 2013 CONCLUSIONS: AtPAP2 overexpression resulted in a widespread reprogramming of the transcriptome in the transgenic plants, which is characterized by changes in the carbon, nitrogen, potassium, and iron metabolism. Carbon 162-168 Purple acid phosphatases superfamily protein Arabidopsis thaliana 13-19 23530764-3 2013 RESULTS: Results indicate that hMSC differentiation can be enhanced by either culturing in electrically conductive, carbon nanotube-containing composite scaffolds without electrical stimulation in the presence of 5-azacytidine, or extrinsic electrical stimulation in nonconductive poly(epsilon-caprolactone) scaffolds without carbon nanotube and azacytidine. Carbon 326-332 musculin Homo sapiens 31-35 21209714-2 2010 One of these forms, 5,10 methylenetetrahydrofolic acid (CH(2)THF), is the key one-carbon donor and reduced folate substrate for thymidylate synthase (TS). Carbon 82-88 thymidylate synthetase Homo sapiens 128-148 667283-2 1978 Histological and ultrastructural examinations have shown that in FV 3 infected animals part of the inoculated carbon is taken up by the hepatocytes and can be located inside cytoplasmic vesicles or dense bodies. Carbon 110-116 Friend virus susceptibility 3 Mus musculus 65-69 797333-6 1976 We have found a close relation among the sporulation rate, the degree of the degradation of vegetative RNA and the increase in ribonuclease activity in the sporulation medium, using cells of which sporulation ability was repressed by changing the age or carbon source in various degrees. Carbon 254-260 ribonuclease Saccharomyces cerevisiae S288C 127-139 20496440-0 2010 Nanopatterning of catalyst by Dip Pen nanolithography (DPN) for synthesis of carbon nanotubes (CNT). Carbon 77-83 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 34-37 24042582-3 2013 In the bending and tape tests, PEDOT-carbon composite catalyst layers exhibited higher elasticity and better adhesion on all the studied substrates (ITO-PET and ITO-PEN plastic, and FTO-glass), compared to a binder free carbon composite and a TiO2 binder enriched carbon composite, and showed lower charge transfer resistance (1.5-3 Omega cm(2)) than the traditional thermally platinized CE (5 Omega cm(2)), demonstrating better catalytic performance for the tri-iodide reduction reaction. Carbon 37-43 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 165-168 814898-0 1976 Interaction of 13C-enriched folate with dihydrofolate reductase studies by carbon magnetic resonance spectroscopy. Carbon 75-81 dihydrofolate reductase Homo sapiens 40-63 24042582-3 2013 In the bending and tape tests, PEDOT-carbon composite catalyst layers exhibited higher elasticity and better adhesion on all the studied substrates (ITO-PET and ITO-PEN plastic, and FTO-glass), compared to a binder free carbon composite and a TiO2 binder enriched carbon composite, and showed lower charge transfer resistance (1.5-3 Omega cm(2)) than the traditional thermally platinized CE (5 Omega cm(2)), demonstrating better catalytic performance for the tri-iodide reduction reaction. Carbon 37-43 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 182-185 24042582-4 2013 Also the TiO2 binder enriched carbon composite showed good catalytic characteristics and relatively good adhesion on ITO-PET, but on ITO-PEN its adhesion was poor. Carbon 30-36 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 137-140 24108357-2 2013 AMPK"s homolog in the yeast Saccharomyces cerevisiae, the SNF1 protein kinase, is a central regulator of carbon metabolism that inhibits the Snf3/Rgt2-Rgt1 glucose sensing pathway and activates genes involved in respiration. Carbon 105-111 glucose sensor Saccharomyces cerevisiae S288C 146-150 22219698-2 2010 This work was devoted to the debonding damage detection of lap splice joints in carbon fiber reinforced plastic (CFRP) structures, which is based on guided ultrasonic wave signals captured by using fiber optic Doppler (FOD) sensor with spiral shape. Carbon 80-86 LAP Homo sapiens 59-62 20024249-2 2009 Hexa-substituted benzene derivatives show larger two-photon cross sections than the corresponding dipolar counterparts and the largest values of delta(max) = 2000 GM and delta(max)/MW = 2.25 GM g(-1) have been obtained with a compound having C[triple bond]C and C=C bonds in the conjugation bridge. Carbon 242-243 hexosaminidase subunit alpha Homo sapiens 0-4 20024249-2 2009 Hexa-substituted benzene derivatives show larger two-photon cross sections than the corresponding dipolar counterparts and the largest values of delta(max) = 2000 GM and delta(max)/MW = 2.25 GM g(-1) have been obtained with a compound having C[triple bond]C and C=C bonds in the conjugation bridge. Carbon 256-257 hexosaminidase subunit alpha Homo sapiens 0-4 807558-4 1975 Addition of glucose or other carbon sources to a culture after consumption of the initial carbon source led to an inactivation of the extracellular beta-1,3-glucanase by an inactivating system, which could be separated from the cells. Carbon 29-35 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 148-156 23954926-2 2013 Afterwards, a carbon paste electrode (CPE) was modified with GNS by casting and drying GNS on top of the CPE (CPE/GNS). Carbon 14-20 carboxypeptidase E Homo sapiens 38-41 23954926-2 2013 Afterwards, a carbon paste electrode (CPE) was modified with GNS by casting and drying GNS on top of the CPE (CPE/GNS). Carbon 14-20 glucosamine (N-acetyl)-6-sulfatase Homo sapiens 61-64 23954926-2 2013 Afterwards, a carbon paste electrode (CPE) was modified with GNS by casting and drying GNS on top of the CPE (CPE/GNS). Carbon 14-20 glucosamine (N-acetyl)-6-sulfatase Homo sapiens 87-90 23954926-2 2013 Afterwards, a carbon paste electrode (CPE) was modified with GNS by casting and drying GNS on top of the CPE (CPE/GNS). Carbon 14-20 carboxypeptidase E Homo sapiens 110-117 807558-4 1975 Addition of glucose or other carbon sources to a culture after consumption of the initial carbon source led to an inactivation of the extracellular beta-1,3-glucanase by an inactivating system, which could be separated from the cells. Carbon 90-96 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 148-156 19776008-4 2009 We now present evidence that the FPP-derived, 20-carbon molecule geranylgeranyl pyrophosphate (GGPP) is a potent endogenous regulator of Hmg2p degradation. Carbon 49-55 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 Saccharomyces cerevisiae S288C 137-142 1133823-8 1975 For comparison, the trans-1-methoxy-2-acetamide (16) was obtained through a dnown resin-catalyzed methoxy migration from C-9A TO C-1 IN MITOMYCIN C. The use of 1-H nmr spectroscopy to asign configurations to 1,2-disubstituted mitosenes is discussed. Carbon 121-122 heterogeneous nuclear ribonucleoprotein C Homo sapiens 129-132 19902945-5 2009 The unusual reactivity of 4 is likely to result from the contribution of an ionized carbene-type resonance structure that facilitates nucleophilic addition to the most electrophilic carbon atom (C-4) in this charged radical. Carbon 182-188 complement C4A (Rodgers blood group) Homo sapiens 195-198 19908864-1 2009 In oxygenic photosynthetic cells, carbon metabolism is regulated by a light-dependent redox signaling pathway through which the light signal is transmitted in the form of electrons via a redox chain comprising ferredoxin (Fd), ferredoxin:thioredoxin reductase (FTR), and thioredoxin (Trx). Carbon 34-40 thioredoxin Homo sapiens 238-249 19908864-1 2009 In oxygenic photosynthetic cells, carbon metabolism is regulated by a light-dependent redox signaling pathway through which the light signal is transmitted in the form of electrons via a redox chain comprising ferredoxin (Fd), ferredoxin:thioredoxin reductase (FTR), and thioredoxin (Trx). Carbon 34-40 thioredoxin Homo sapiens 271-282 19908864-1 2009 In oxygenic photosynthetic cells, carbon metabolism is regulated by a light-dependent redox signaling pathway through which the light signal is transmitted in the form of electrons via a redox chain comprising ferredoxin (Fd), ferredoxin:thioredoxin reductase (FTR), and thioredoxin (Trx). Carbon 34-40 thioredoxin Homo sapiens 284-287 24024653-3 2013 DFT calculations at the B3LYP/6-311++G(d,p) level show that HCN can form in-plane hydrogen bonds to ring hydrogens, or bind electrostatically to positively charged carbon centers in the ring. Carbon 164-170 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 60-63 4791484-5 1973 Esters of polyglycerols (tri-, hexa-, and decaglycerol esters) were generally active when the fatty acid had chain lengths of 8 to 12 carbon atoms. Carbon 134-140 hexosaminidase subunit alpha Homo sapiens 31-35 23892137-2 2013 Two C-DIM analogs, DIM-C-pPhOCH3 (C-DIM-5) and DIM-C-pPhOH (C-DIM-8) while acting differentially on the orphan nuclear receptor, TR3/Nur77 inhibited cell cycle progression from G0/G1 to S-phase and induced apoptosis in A549 cells. Carbon 4-5 nuclear receptor subfamily 4, group A, member 1 Mus musculus 129-132 23892137-2 2013 Two C-DIM analogs, DIM-C-pPhOCH3 (C-DIM-5) and DIM-C-pPhOH (C-DIM-8) while acting differentially on the orphan nuclear receptor, TR3/Nur77 inhibited cell cycle progression from G0/G1 to S-phase and induced apoptosis in A549 cells. Carbon 4-5 nuclear receptor subfamily 4, group A, member 1 Mus musculus 133-138 23886539-3 2013 The soil sorption coefficient normalized to the organic carbon content (Koc) is a key parameter that is used in environmental risk assessments. Carbon 56-62 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 72-75 23930863-6 2013 After that, the nucleophilic sulfur anion of Cys603 in SENP1 attacked the carbonyl carbon of Gly97 of SUMO1 to trigger the reaction, and then a tetrahedral intermediate and an acyl-enzyme intermediate were generated in turn, leading to the final release of enzyme SENP1 and two products, free SUMO1 and RanGAP1. Carbon 74-80 Ran GTPase activating protein 1 Homo sapiens 303-310 20009329-1 2009 A trioctylamine (TOA) modified carbon paste electrode (TOA/CPE) was firstly utilized to determine Cr(VI) in electronics materials. Carbon 31-37 carboxypeptidase E Homo sapiens 59-62 19852486-0 2009 Dip-pen nanolithography of electrical contacts to single-walled carbon nanotubes. Carbon 64-70 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 4-7 5275374-3 1970 This reaction can be formulated as an abstraction of hydrogen from the C-21-hydroxyl group to form a C-21-alkoxy radical, followed by a 1,5-H.shift from the C-16 atom and beta-scission of the C-16-alkoxy radical leading to the loss of a C(2) fragment (C-20 and C-21) with the formation of the double bond between C-16 and C-17. Carbon 71-72 cytokine like 1 Homo sapiens 322-326 20032389-11 2009 CONCLUSION: CHAP31 sensitizes SCC cells to carbon-ion radiotherapy and this combinatory treatment may be a potentially useful therapeutic strategy for esophageal SCC. Carbon 43-49 serpin family B member 3 Homo sapiens 30-33 32261116-2 2013 In this study, we developed a carbon nanodot (C-dot)-based miR124a molecular beacon (miR124a CMB). Carbon 30-36 ubiquitin like 5 Homo sapiens 77-83 5275374-3 1970 This reaction can be formulated as an abstraction of hydrogen from the C-21-hydroxyl group to form a C-21-alkoxy radical, followed by a 1,5-H.shift from the C-16 atom and beta-scission of the C-16-alkoxy radical leading to the loss of a C(2) fragment (C-20 and C-21) with the formation of the double bond between C-16 and C-17. Carbon 101-102 cytokine like 1 Homo sapiens 322-326 19565191-1 2009 Monosuccinyl beta-cyclodextrin (succinyl-beta-CD) was synthesized and the selectivity to quercetin and rutin of the succinyl-beta-CD-modified, multi-wall carbon nanotube (MWNT)-coated, glassy carbon electrode [(succinyl-beta-CD + MWNT)/GCE] was investigated. Carbon 154-160 aminomethyltransferase Homo sapiens 236-239 5802639-1 1969 The rate at which rat pancreatic lipase (glycerol-ester hydrolase, EC 3.1.1.3) hydrolyzes the esters of primary n-alcohols containing from 1 to 18 carbon atoms with fatty acids containing from 2 to 18 carbon atoms was determined. Carbon 147-153 pancreatic lipase Rattus norvegicus 22-39 19619160-10 2009 Taken together, these findings indicate that KCS20 and KCS2/DAISY are functionally redundant in the two-carbon elongation to C(22) VLCFA that is required for cuticular wax and root suberin biosynthesis. Carbon 104-110 3-ketoacyl-CoA synthase 20 Arabidopsis thaliana 45-50 23624016-2 2013 In this study, a rapid, sensitive and selective molecularly imprinted electrochemical sensor for QCA determination was successfully constructed by combination of a novel modified glassy carbon electrode (GCE) and differential pulse voltammetry (DPV). Carbon 186-192 guanylate cyclase 2E, pseudogene Homo sapiens 204-207 23624016-3 2013 The GCE was fabricated via stepwise modification of multi-walled carbon nanotubes (MWNTs)-chitosan (CS) functional composite and a sol-gel molecularly imprinted polymer (MIP) film on the surface. Carbon 65-71 guanylate cyclase 2E, pseudogene Homo sapiens 4-7 5802639-1 1969 The rate at which rat pancreatic lipase (glycerol-ester hydrolase, EC 3.1.1.3) hydrolyzes the esters of primary n-alcohols containing from 1 to 18 carbon atoms with fatty acids containing from 2 to 18 carbon atoms was determined. Carbon 201-207 pancreatic lipase Rattus norvegicus 22-39 5358248-0 1969 Electronmicroscopic localization of cholinesterase at the neuromuscular junction by a quaternary carbon analogue of acetylthiocholine as substrate. Carbon 97-103 butyrylcholinesterase Homo sapiens 36-50 24004143-2 2013 It contains a rare carbon-centered (distorted) Ni6C octahedral core decorated by four Au(PPh3) fragments. Carbon 19-25 protein phosphatase 4 catalytic subunit Homo sapiens 89-93 19778056-6 2009 On the basis of the proposed mechanism, the glyoxal interaction with alanine through a decarboxylative aldol addition reaction can lead to the formation of 1,2-butanedione with the terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine, and the similar interaction of 1,2-butanedione with a second molecule of alanine can lead to the formation of 3,4-hexanedione with both terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine. Carbon 409-415 complement C2 Homo sapiens 226-229 19778056-6 2009 On the basis of the proposed mechanism, the glyoxal interaction with alanine through a decarboxylative aldol addition reaction can lead to the formation of 1,2-butanedione with the terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine, and the similar interaction of 1,2-butanedione with a second molecule of alanine can lead to the formation of 3,4-hexanedione with both terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine. Carbon 409-415 complement C2 Homo sapiens 439-442 19849830-2 2009 Reduced carbon and nitrogen precursor compounds for the synthesis of HCN may be formed under off-axis hydrothermal conditions in oceanic lithosphere in the presence of native Fe and Ni and are adsorbed on authigenic layer silicates and zeolites. Carbon 8-14 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 69-72 23881167-1 2013 A novel bio-inspired Pt- and FTO-free integrated pure carbon counter electrode (CE) for dye-sensitized solar cells (DSSCs) has been designed and fabricated using a porous carbon sheet as a conducting substrate and ordered mesoporous carbon (OMC) as the catalytic layer. Carbon 54-60 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 29-32 33780773-0 2021 Aqueous Nd3+ capture using a carboxyl-functionalized porous carbon derived from ZIF-8. Carbon 60-66 mitochondrially encoded NADH dehydrogenase 3 Homo sapiens 8-11 23881167-1 2013 A novel bio-inspired Pt- and FTO-free integrated pure carbon counter electrode (CE) for dye-sensitized solar cells (DSSCs) has been designed and fabricated using a porous carbon sheet as a conducting substrate and ordered mesoporous carbon (OMC) as the catalytic layer. Carbon 171-177 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 29-32 23881167-1 2013 A novel bio-inspired Pt- and FTO-free integrated pure carbon counter electrode (CE) for dye-sensitized solar cells (DSSCs) has been designed and fabricated using a porous carbon sheet as a conducting substrate and ordered mesoporous carbon (OMC) as the catalytic layer. Carbon 171-177 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 29-32 19826036-5 2009 In SF188 glioblastoma cells, glucose deprivation did not affect net glutamine utilization but elicited a switch in the pathways used to deliver glutamine carbon to the tricarboxylic acid cycle, with a large increase in the activity of glutamate dehydrogenase (GDH). Carbon 154-160 glutamate dehydrogenase 1 Homo sapiens 260-263 19774297-1 2009 Progressive addition of hydroxypropylated amylose (AmH), from 0.05 wt% to 4.5 wt%, to single-walled carbon nanotubes (SWNTs) in aqueous surfactant suspensions quenches the intrinsic near Infra-Red fluorescence of semiconducting SWNTs while dispersions obtained with a same amount of polyvinylpyrrolidone (PVP) remain luminescent. Carbon 100-106 anti-Mullerian hormone Homo sapiens 51-54 33780773-2 2021 Then, the carbon was functionalized with carboxylic groups and applied for separation of neodymium ions (Nd3+) from water. Carbon 10-16 mitochondrially encoded NADH dehydrogenase 3 Homo sapiens 105-108 33901643-7 2021 The kinetic studies established the compounds as novel activators of PKM2 and (E/Z)-(4-(3-(2-((4-chlorophenyl)amino)-4-(dimethylamino)thiazol-5-yl)-2-(ethoxycarbonyl)-3-oxoprop-1-en-1-yl) phenyl)boronic acid (6c) emerged as the most potent derivative. Carbon 209-211 pyruvate kinase M1/2 Homo sapiens 69-73 19728306-1 2009 In this report, a novel carbon nanotube/poly(ethylene-co-vinyl acetate) (CNT/EVA) composite electrode was developed for the amperometric detection in CE. Carbon 24-30 myelin protein zero like 2 Homo sapiens 77-80 19617454-9 2009 L-FABP was upregulated by PFCs greater than or equal to eight carbons, while CYPs were upregulated by PFCs less than or equal to eight carbons. Carbon 62-69 fatty acid binding protein 1 Gallus gallus 0-6 19663434-3 2009 The correlations obtained for PF2/6 indicate that the (13)C chemical shifts of the aromatic carbons close to the intermonomer connection (C1, C2, and C3) have minimum values at planar conformations (0 degrees and 180 degrees ) and maximum values at 90 degrees conformations. Carbon 92-99 heterogeneous nuclear ribonucleoprotein C Homo sapiens 138-152 19631531-0 2009 Synthesis of sialic acid derivatives having a C=C double bond substituted at the C-5 position and their glycopolymers. Carbon 46-47 complement C5 Homo sapiens 81-84 19631531-0 2009 Synthesis of sialic acid derivatives having a C=C double bond substituted at the C-5 position and their glycopolymers. Carbon 48-49 complement C5 Homo sapiens 81-84 19695441-10 2009 CONCLUSIONS: These data demonstrate that the HRS/IRR by carbon ion radiation is an ATM-dependent phenomenon in the cellular response to DNA damage. Carbon 56-62 ATM serine/threonine kinase Homo sapiens 83-86 19563773-1 2009 Phosphorus-containing pseudopeptides, racemic at the C-terminal alpha-carbon, are potent mechanism-based inhibitors of folylpolyglutamate synthetase (FPGS). Carbon 70-76 folylpolyglutamate synthase Homo sapiens 119-148 19563773-1 2009 Phosphorus-containing pseudopeptides, racemic at the C-terminal alpha-carbon, are potent mechanism-based inhibitors of folylpolyglutamate synthetase (FPGS). Carbon 70-76 folylpolyglutamate synthase Homo sapiens 150-154 21577535-1 2009 In the enanti-omerically pure title compound, C(11)H(19)N(3)O(3)S, the chain C-N-C(O)-O-C-C (from the asymmetric carbon to a methyl of the tert-butyl group) displays an extended conformation. Carbon 46-47 telomerase reverse transcriptase Homo sapiens 139-143 21577535-1 2009 In the enanti-omerically pure title compound, C(11)H(19)N(3)O(3)S, the chain C-N-C(O)-O-C-C (from the asymmetric carbon to a methyl of the tert-butyl group) displays an extended conformation. Carbon 77-78 telomerase reverse transcriptase Homo sapiens 139-143 21577535-1 2009 In the enanti-omerically pure title compound, C(11)H(19)N(3)O(3)S, the chain C-N-C(O)-O-C-C (from the asymmetric carbon to a methyl of the tert-butyl group) displays an extended conformation. Carbon 77-78 telomerase reverse transcriptase Homo sapiens 139-143 21577535-1 2009 In the enanti-omerically pure title compound, C(11)H(19)N(3)O(3)S, the chain C-N-C(O)-O-C-C (from the asymmetric carbon to a methyl of the tert-butyl group) displays an extended conformation. Carbon 77-78 telomerase reverse transcriptase Homo sapiens 139-143 21577535-1 2009 In the enanti-omerically pure title compound, C(11)H(19)N(3)O(3)S, the chain C-N-C(O)-O-C-C (from the asymmetric carbon to a methyl of the tert-butyl group) displays an extended conformation. Carbon 113-119 telomerase reverse transcriptase Homo sapiens 139-143 19455312-0 2009 Tip-enhanced near-field optical microscopy of carbon nanotubes. Carbon 46-52 TOR signaling pathway regulator Homo sapiens 0-3 19455312-1 2009 We review recent experimental studies on single-walled carbon nanotubes on substrates using tip-enhanced near-field optical microscopy (TENOM). Carbon 55-61 TOR signaling pathway regulator Homo sapiens 92-95 19569659-1 2009 This paper presents an application of the reaction class transition state theory (RC-TST) to predict thermal rate constants for hydrogen abstraction reactions of the type C(2)H(3) + alkane --> C(2)H(4) + alkyl radical. Carbon 83-84 thiosulfate sulfurtransferase Homo sapiens 85-88 19488452-4 2009 Moreover, the electrochemical properties of the title complex bulk-modified carbon paste electrode (La-CPE) have been studied, and the results indicate that the La-CPE has good electrocatalytic activities towards the reduction of hydrogen peroxide, nitrite, bromate and trichloroacetic acid (TCA). Carbon 76-82 carboxypeptidase E Homo sapiens 103-106 19488452-4 2009 Moreover, the electrochemical properties of the title complex bulk-modified carbon paste electrode (La-CPE) have been studied, and the results indicate that the La-CPE has good electrocatalytic activities towards the reduction of hydrogen peroxide, nitrite, bromate and trichloroacetic acid (TCA). Carbon 76-82 carboxypeptidase E Homo sapiens 164-167 19403143-0 2009 Simultaneous adsorption of Cd2+ and phenol on modified N-doped carbon nanotubes: experimental and DFT studies. Carbon 63-69 CD2 molecule Homo sapiens 27-30 19522016-0 2009 MEKC-LIF analysis of rhodamine123 delivered by carbon nanotubes in K562 cells. Carbon 47-53 LIF interleukin 6 family cytokine Homo sapiens 5-8 18996626-6 2009 Further SAR studies of GA derivatives indicated that modification of carbon-carbon double bond at C-32/33 or C-37/38 and of the methyl groups at C-39/C-35 can improve antitumor activity. Carbon 76-82 chemokine like factor Homo sapiens 98-102 19402670-5 2009 The potential energy surface of the C(6)H(7)Si(+) system was constructed by B3LYP and MP2 methods using an aug-cc-pVDZ basis set. Carbon 36-37 tryptase pseudogene 1 Homo sapiens 86-89 19423004-3 2009 Here, we report the in vitro cell-binding properties and biodistribution and SPECT/CT imaging in glioma (U87MG) xenograft-bearing mice of (125)I-labeled c-Met-binding peptides (cMBPs) including analogs conjugated to amino acid and aliphatic carbon linkers. Carbon 241-247 met proto-oncogene Mus musculus 153-158 19243205-3 2009 Both MP2 and SCS-MP2 geometry optimizations yield a T-shaped structure with a N--H...pi hydrogen bond to the benzene ring and the C=O group above, but far from the C--H bonds of benzene. Carbon 14-15 tryptase pseudogene 1 Homo sapiens 17-20 19158217-7 2009 SHMT-mediated conversion of glycine to serine increased from 182 +/- 7 to 205 +/- 9 micromol x kg(-1) x h(-1) (P < 0.05), but serine production using a GCS-derived 1-carbon unit (93 +/- 9 vs. 91 +/- 6 micromol x kg(-1) x h(-1)) and glycine cleavage (163 +/- 11 vs. 151 +/- 8 micromol x kg(-1) x h(-1)) were not changed by vitamin B-6 restriction. Carbon 169-175 serine hydroxymethyltransferase 1 Homo sapiens 0-4 19199636-2 2009 The chemical process involves two proton transfers, one from a carbon of the substrate to the nitrogen of Pro1 and another from this nitrogen atom to a different carbon of the substrate. Carbon 63-69 lamin A/C Homo sapiens 106-110 18829300-1 2009 The direct electron transfer of myoglobin (Mb) was realized by immobilizing Mb onto ionic liquid (1-butyl-3-methyl imidazolium tetrafluoraborate, [bmim][BF(4)])-clay composite film modified glassy carbon electrode. Carbon 197-203 myoglobin Homo sapiens 32-41 18829300-1 2009 The direct electron transfer of myoglobin (Mb) was realized by immobilizing Mb onto ionic liquid (1-butyl-3-methyl imidazolium tetrafluoraborate, [bmim][BF(4)])-clay composite film modified glassy carbon electrode. Carbon 197-203 myoglobin Homo sapiens 43-45 18829300-1 2009 The direct electron transfer of myoglobin (Mb) was realized by immobilizing Mb onto ionic liquid (1-butyl-3-methyl imidazolium tetrafluoraborate, [bmim][BF(4)])-clay composite film modified glassy carbon electrode. Carbon 197-203 myoglobin Homo sapiens 76-78 19334611-6 2009 Mutation sup35-AGG1 (ATG1-->AGG) causes the lethal effect in cells grown on media containing glucose as the sole source of carbon. Carbon 126-132 serine/threonine protein kinase ATG1 Saccharomyces cerevisiae S288C 21-25 20355754-0 2009 SERS study of the controllable release of nitric oxide from aromatic nitrosothiols on bimetallic, bifunctional nanoparticles supported on carbon nanotubes. Carbon 138-144 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 0-4 23872724-0 2013 Orthorhombic C32: a novel superhard sp3 carbon allotrope. Carbon 40-46 chemokine like factor Homo sapiens 13-16 22707151-5 2013 Increasing extracellular concentrations of insulin did not affect leucine transamination or oxidative decarboxylation, but decreased the rate of oxidation of leucine carbons 2-6. Carbon 166-173 insulin Bos taurus 43-50 23820848-2 2013 OBJECTIVES: We investigated the association between long-term exposure to black carbon, a correlate of traffic particles, and intima-media thickness of the common carotid artery (CIMT) in elderly men residing in the greater Boston, Massachusetts, area. Carbon 80-86 CIMT Homo sapiens 179-183 27137392-6 2013 CP12 plays an important role in the regulation of the Calvin-Benson-Bassham Cycle participating in the assembly of a supramolecular complex between phosphoribulokinase and glyceraldehyde 3-phosphate dehydrogenase, indicating that calcium signaling could play a role in regulating carbon fixation. Carbon 280-286 CP12 domain-containing protein 2 Arabidopsis thaliana 0-4 23940783-0 2013 Poly (C)-binding protein 1 regulates p63 expression through mRNA stability. Carbon 6-7 tumor protein p63 Homo sapiens 37-40 23607494-8 2013 Furthermore, poly(I:C) and proinflammatory cytokines [(IL-1beta, interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha] induced IL-32 expression strongly in cultured BECs, accompanying the constant expression of TLR-3 and caspase 1. Carbon 20-21 interleukin 32 Homo sapiens 136-141 23845478-1 2013 Norepinephrine (NE) is detected amperometrically using the enzyme Phenylethanolamine N-methyl transferase and cofactor S-(5"-Adenosyl)-l-methionine chloride dihydrochloride with disposable screen printed mesoporous carbon electrodes. Carbon 215-221 phenylethanolamine N-methyltransferase Oryctolagus cuniculus 66-105 23706115-9 2013 However, chains with an odd-number of carbon atoms, C17, C19, , have very intense transitions in the region above 4400 A and remain attractive candidates. Carbon 38-44 cytokine like 1 Homo sapiens 52-55 23671037-1 2013 OBJECTIVE: Investigation was conducted to understand the mechanism of action of diacylglycerol acyltransferase 1 (DGAT1) using small molecules DGAT1 inhibitors, compounds K and L. DESIGN AND METHODS: Biochemical and stable-label tracer approaches were applied to interrogate the functional activities of compounds K and L on TG synthesis and changes of carbon flow. Carbon 353-359 diacylglycerol O-acyltransferase 1 Mus musculus 80-112 23671037-1 2013 OBJECTIVE: Investigation was conducted to understand the mechanism of action of diacylglycerol acyltransferase 1 (DGAT1) using small molecules DGAT1 inhibitors, compounds K and L. DESIGN AND METHODS: Biochemical and stable-label tracer approaches were applied to interrogate the functional activities of compounds K and L on TG synthesis and changes of carbon flow. Carbon 353-359 diacylglycerol O-acyltransferase 1 Mus musculus 114-119 23671037-9 2013 DGAT1 inhibition leads to enhanced PC production via alternative carbon channeling. Carbon 65-71 diacylglycerol O-acyltransferase 1 Mus musculus 0-5 23706549-2 2013 In the current study, N-(11)C-methylated compound of NCFB, [(11)C]Me-NCFB was synthesized and evaluated for the visualization of BACE1 in brain. Carbon 28-29 beta-site APP cleaving enzyme 1 Mus musculus 129-134 23614840-1 2013 A Sc(OTf)3-catalyzed three-component cyclization reaction of arylamines, beta,gamma-unsaturated alpha-ketoesters and 1,3-dicarbonyl compounds was developed to synthesize highly substituted 1,4-dihydropyridines and fused bicyclic tetrahydropyridines carrying a quaternary all-carbon center. Carbon 123-129 POU class 5 homeobox 1 Homo sapiens 2-10 23678976-2 2013 The key features of its preparation are: (i) a stereoselective boron-aldol reaction to afford the acyclic carbon skeleton of the methylenecylopentane moiety; (ii) its cyclization by a Cp2TiCl-catalyzed intramolecular radical addition of an epoxide to an alkyne; and (iii) the coupling with a purine derivative by a Mitsunobu reaction. Carbon 106-112 ceruloplasmin Homo sapiens 184-187 23399389-1 2013 An improved D-amino acid biosensor was constructed based on covalent immobilization of D-amino acid oxidase onto carboxylated mutliwalled carbon nanotube/copper nanoparticles/polyalinine hybrid film electrodeposited on gold electrode. Carbon 138-144 D-amino acid oxidase Homo sapiens 87-107 23877440-7 2013 We found that a significant fraction (>0.1 mol%) of the vaporized carbon is converted to HCN and cyanide condensates, even when the ambient gas contains as much as a few hundred mbar of CO2. Carbon 69-75 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 92-95 23398733-8 2013 The results show that Trx f is a more effective regulator of photosynthetic carbon metabolism in planta than Trx m. The overexpression of Trx f might therefore provide a means of increasing the carbohydrate content of plants destined for use in biofuel production. Carbon 76-82 thioredoxin H-type 1 Nicotiana tabacum 22-25 23717603-0 2013 Repair of abdominal wall defects in vitro and in vivo using VEGF sustained-release multi-walled carbon nanotubes (MWNT) composite scaffolds. Carbon 96-102 vascular endothelial growth factor A Rattus norvegicus 60-64 23717603-3 2013 Multi-walled carbon nanotubes (MWNTs) can more effectively transport VEGF to cells or tissues because of their large specific surface area and interior cavity. Carbon 13-19 vascular endothelial growth factor A Rattus norvegicus 69-73 23578032-5 2013 The question is then why family GT6 members, like bovine alpha1,3-galactosyltransferase (alpha1,3-GalT), have a nucleophilic residue (Glu317) situated close to the anomeric carbon. Carbon 173-179 N-acetyllactosaminide alpha-1,3-galactosyltransferase Bos taurus 57-87 23578032-5 2013 The question is then why family GT6 members, like bovine alpha1,3-galactosyltransferase (alpha1,3-GalT), have a nucleophilic residue (Glu317) situated close to the anomeric carbon. Carbon 173-179 N-acetyllactosaminide alpha-1,3-galactosyltransferase Bos taurus 89-102 23567667-2 2013 The biocatalytic reactions were catalyzed by Candida antarctica lipase B immobilized onto various functionalized multi-walled carbon nanotubes (f-CNTs-CaLB), as well as by commercial Novozym 435. Carbon 126-132 PAN0_003d1715 Moesziomyces antarcticus 64-70 23202341-1 2013 In this paper, chitosan-prussian blue-multiwall carbon nanotubes-hollow gold nanospheres (Chit-PB-MWNTs-HGNs) film was fabricated onto the gold electrode surface by one-step electrodeposition method; and then acetylcholinesterase (AChE) and Nafion were modified onto the film to prepare an AChE biosensor. Carbon 48-54 chitinase 1 Homo sapiens 90-94 23404040-0 2013 Atmospheric microplasma-functionalized 3D microfluidic strips within dense carbon nanotube arrays confine Au nanodots for SERS sensing. Carbon 75-81 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 122-126 23519668-5 2013 The N atom in the azaalkyl chain of DAAM-3 is located at almost the same position as the N-methyl C atom of the methylated lysine side chain in the substrate-peptide complex structures and stabilizes complex formation by hydrogen bonding to the substrate-binding site residues of SET7/9. Carbon 98-99 SET domain containing 7, histone lysine methyltransferase Homo sapiens 280-286 23436231-0 2013 Does addition of NO2 to carbon-centered radicals yield RONO or RNO2? Carbon 24-30 NLR family pyrin domain containing 12 Homo sapiens 63-67 23643002-1 2013 OBJECTIVE: To explore the role of laparoscopic sentinel lymph node(SLN) detection with carbon nanoparticles tracer in cervical carcinoma. Carbon 87-93 sarcolipin Homo sapiens 67-70 23643002-6 2013 CONCLUSION: Laparoscopic SLN detection with carbon nanoparticles tracer is a relative safe and sensitive method for in cervical carcinoma. Carbon 44-50 sarcolipin Homo sapiens 25-28 23401322-0 2013 Probing arginine side-chains and their dynamics with carbon-detected NMR spectroscopy: application to the 42 kDa human histone deacetylase 8 at high pH. Carbon 53-59 histone deacetylase 8 Homo sapiens 119-140 24285318-10 2013 To date, two H4 R-specific (11) C-labeled ligands have been synthesized, and the imaging of the H4 R in vivo is in the early stage. Carbon 32-33 histamine receptor H4 Homo sapiens 13-17 24285318-10 2013 To date, two H4 R-specific (11) C-labeled ligands have been synthesized, and the imaging of the H4 R in vivo is in the early stage. Carbon 32-33 histamine receptor H4 Homo sapiens 96-100 22931212-8 2013 When AD-C was incubated with phosphatase, Rib-C1 and Rib-C2 formed. Carbon 8-9 RIB43A domain with coiled-coils 1 Rattus norvegicus 42-48 22931212-8 2013 When AD-C was incubated with phosphatase, Rib-C1 and Rib-C2 formed. Carbon 8-9 RIB43A domain with coiled-coils 2 Rattus norvegicus 53-59 19022396-2 2009 The Coq4 polypeptide is required for Q biosynthesis and growth on non-fermentable carbon sources, however its exact function in this pathway is not known. Carbon 82-88 ubiquinone biosynthesis protein COQ4 Saccharomyces cerevisiae S288C 4-8 19022396-4 2009 A yeast coq4-1 mutant harboring an E226K substitution is unable to grow on nonfermentable carbon sources. Carbon 90-96 ubiquinone biosynthesis protein COQ4 Saccharomyces cerevisiae S288C 8-12 20641442-0 2004 Tri-gadolinium nitride PEGylated-hydroxylated endohedral metallofullerene Fullerenes, also known as buckyballs, are spheroidal carbon cages with a molecular formula of C2n (n = 30-41) and a diameter of ~1 nm (1). Carbon 127-133 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 0-3 18346891-3 2008 581 U endoglucanase activity, 243 U filter paper activity and 128 U beta-glucosidase activity per gram of carbon source were obtained in the optimal condition. Carbon 106-112 beta-glucosidase Zea mays 68-84 33930349-0 2021 Statins repress needle-like carbon nanotube- or cholesterol crystal-stimulated IL-1beta production by inhibiting the uptake of crystals by macrophages. Carbon 28-34 interleukin 1 alpha Mus musculus 79-87 18810459-3 2008 These findings demonstrate that CD-1 mice have excellent discrimination ability for structurally related aliphatic odorants, that correlations between discrimination performance and structural similarity of odorants are odorant class-specific rather than a general phenomenon, and that both carbon chain length and type of functional group play an important role for odor quality coding in mice. Carbon 291-297 CD1 antigen complex Mus musculus 32-36 23425360-13 2013 CONCLUSIONS: The Mtb mutant kstD strain, which is unable to use cholesterol as a source of carbon and energy, has a limited ability to multiply in resting MO following infection, reflecting a failure of the kstD strain to inhibit the TLR2-dependent bactericidal activity of resting MO. Carbon 92-98 3-oxosteroid 1-dehydrogenase Mycobacterium tuberculosis H37Rv 29-33 33601106-2 2021 Herein, we demonstrate an interfacial engineering strategy to prepare Fe-doped CoP nanocubes/CoP nanosheet arrays heterostructure supported on carbon cloth (denoted as CoFeP/CoP/CC). Carbon 143-149 caspase recruitment domain family member 16 Homo sapiens 79-82 23356208-4 2013 The nucleophilic nature of 1 is also demonstrated through its reaction with cis-[Pt(C(6)F(5))(2)(THF)(2)], which results in the formation of [Pt(4)(mu-PPh(2))(4)(C(6)F(5))(4)(PPh(3))] (4). Carbon 84-85 protein phosphatase 4 catalytic subunit Homo sapiens 175-181 33601106-2 2021 Herein, we demonstrate an interfacial engineering strategy to prepare Fe-doped CoP nanocubes/CoP nanosheet arrays heterostructure supported on carbon cloth (denoted as CoFeP/CoP/CC). Carbon 143-149 caspase recruitment domain family member 16 Homo sapiens 93-96 23238458-5 2013 In this work, we provide an alternative explanation for the occurrence of these sets in terms of the specific anchoring sites of the molecule to the tip, which in turn determines the interaction of a portion of the carbon chain with the tip. Carbon 215-221 TOR signaling pathway regulator Homo sapiens 149-152 33601106-2 2021 Herein, we demonstrate an interfacial engineering strategy to prepare Fe-doped CoP nanocubes/CoP nanosheet arrays heterostructure supported on carbon cloth (denoted as CoFeP/CoP/CC). Carbon 143-149 caspase recruitment domain family member 16 Homo sapiens 93-96 23238458-5 2013 In this work, we provide an alternative explanation for the occurrence of these sets in terms of the specific anchoring sites of the molecule to the tip, which in turn determines the interaction of a portion of the carbon chain with the tip. Carbon 215-221 TOR signaling pathway regulator Homo sapiens 237-240 34050236-7 2021 Additionally, berberine significantly decreased the mRNA expressions of Chop (GADD153), Stat1, Stat3, and Fas in poly I:C-induced RAW 264.7 cells. Carbon 72-73 DNA-damage inducible transcript 3 Mus musculus 78-85 23044173-1 2013 A novel cysteic acid modified carbon paste electrode (cysteic acid/CPE) based on electrochemical oxidation of L-cysteine was developed to simultaneously determine ofloxacin and gatifloxacin in the presence of sodium dodecyl benzene sulfonate (SDBS). Carbon 30-36 carboxypeptidase E Homo sapiens 67-70 34043797-13 2021 These findings suggest that some amino acids, such as Trp, Cys and Met, have good potential as radioprotectors for preventing DNA damage in normal tissues in carbon-ion therapy. Carbon 158-164 SAFB like transcription modulator Homo sapiens 67-70 23160801-13 2013 The results of this study suggest that the aberrations in one-carbon metabolism appear to induce altered gene expression of EC-SOD, GSTP1, and BNIP3, and thus contribute to the increased oxidative stress and increased susceptibility to CAD. Carbon 62-68 glutathione S-transferase pi 1 Homo sapiens 132-137 23149626-1 2013 Carbon containing nano-sized molybdenum sulfide composites (MoS(x)C(y)) obtained by thermal decomposition reactions of (R(4)N)(2)MoS(4) (R = -H (C(0)), -CH(3) (C(1)), -C(3)H(7) (C(3)), and -C(6)H(13) (C(6))) show promising performance in visible-light driven photocatalytic hydrogen generation. Carbon 0-6 heterogeneous nuclear ribonucleoprotein C Homo sapiens 160-164 34021662-8 2021 Finally, protecting mangrove forests in the northern and southern Red Sea that act as major carbon sinks could help offset greenhouse gas emissions. Carbon 92-98 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 70-73 23267094-5 2013 In both embryos and adults, MTHFD1L catalyzes the last step in the flow of one-carbon units from mitochondria to cytoplasm, producing formate from 10-formyl-THF. Carbon 79-85 thin fur Mus musculus 29-32 23046410-7 2013 On the basis of structural modelling and comparison, as well as large-scale sequence alignment studies, we further determined that the catalytic mechanism of Cg1458 is actually through a glutamic acid-histidine-water triad, and this catalytic triad is common among FAH family proteins that catalyse the cleavage of the C-C bond of the substrate. Carbon 158-159 fumarylacetoacetate hydrolase Homo sapiens 265-268 34045854-2 2021 Here, we present an electrochemical biosensor for PML/RARalpha fusion gene detection using carbon dots functionalized graphene oxide (CDs/GO) nanocomposites modified glassy carbon electrode (CDs/GO/GCE). Carbon 91-97 PML nuclear body scaffold Homo sapiens 50-53 22954322-0 2013 Cytokine and chemokine secretion induced by poly(I:C) through NF-kappaB and phosphoinositide 3-kinase signaling pathways in human corneal fibroblasts. Carbon 0-1 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Homo sapiens 76-101 23862620-5 2013 In the past half decade, deorphanization of several GPCRs has revealed that GPR40, GPR41, GPR43, GPR84 and GPR120 sense concentration of extracellular FFAs with various carbon chain lengths. Carbon 169-175 free fatty acid receptor 1 Homo sapiens 76-81 23199576-4 2013 Carbon isotopic data suggest a wide range of foraging strategies, characterized by mixed C(3)/C(4) to C(4)-dominated diets in wooded grasslands to open woodlands. Carbon 0-6 complement C4A (Rodgers blood group) Homo sapiens 94-98 23199576-4 2013 Carbon isotopic data suggest a wide range of foraging strategies, characterized by mixed C(3)/C(4) to C(4)-dominated diets in wooded grasslands to open woodlands. Carbon 0-6 complement C4A (Rodgers blood group) Homo sapiens 102-106 23164935-3 2013 In order to improve the utility of aptamers as siRNA delivery vehicles, we chemically synthesized the gp120 aptamer with a 3" 7-carbon linker (7C3), which in turn is attached to a 16-nucleotide 2" OMe/2" Fl GC-rich bridge sequence. Carbon 128-134 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 102-107 23306264-1 2013 A range of commercial granular activated carbon (GAC) media have been assessed as pretreatment technologies for a downstream microfiltration (MF) process. Carbon 41-47 glutaminase Homo sapiens 49-52 23306264-4 2013 Comparison with previous work using powdered activated carbon (PAC) revealed that for organic removal above 60% the use of GAC media incurs a significantly lower carbon usage rate than PAC. Carbon 55-61 glutaminase Homo sapiens 123-126 23306264-4 2013 Comparison with previous work using powdered activated carbon (PAC) revealed that for organic removal above 60% the use of GAC media incurs a significantly lower carbon usage rate than PAC. Carbon 162-168 glutaminase Homo sapiens 123-126 22921904-6 2012 When stimulated with Poly (I:C) in vivo, attenuated accumulating in the liver and weaker expression of GranzymeB, TRAIL and FasL of NK1.1(+)CD3(-) cells were observed of IFN-gamma(-/-) mice. Carbon 29-30 granzyme B Homo sapiens 103-112 22921904-6 2012 When stimulated with Poly (I:C) in vivo, attenuated accumulating in the liver and weaker expression of GranzymeB, TRAIL and FasL of NK1.1(+)CD3(-) cells were observed of IFN-gamma(-/-) mice. Carbon 29-30 Fas ligand Homo sapiens 124-128 22970432-1 2012 This paper reports for the first time the development of a large-scale SERS substrate from a popcorn-shaped gold nanoparticle-functionalized single walled carbon nanotubes hybrid thin film for the selective and highly sensitive detection of explosive TNT material at a 100 femtomolar (fM) level. Carbon 155-161 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 71-75 22871463-2 2012 A two carbon bridge connecting the C-2 and C-5 atoms of the pyranose ring allows a torsion of the sugar ring toward a (2,5)B conformation as confirmed by conformational analysis. Carbon 6-12 complement C2 Homo sapiens 35-38 22871463-2 2012 A two carbon bridge connecting the C-2 and C-5 atoms of the pyranose ring allows a torsion of the sugar ring toward a (2,5)B conformation as confirmed by conformational analysis. Carbon 6-12 complement C5 Homo sapiens 43-46 22915335-3 2012 RGO/HBC-C(11)-MIM[Cl(-)] was comprehensively characterized by using atomic force microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, thermogravimetric analysis, and Raman spectroscopy, thus revealing that one HBC-C(11)-MIM[Cl(-)] group can stabilize about 178 carbon atoms on the graphene sheets. Carbon 273-279 keratin 88, pseudogene Homo sapiens 4-7 22961686-2 2012 Here we report on the unequivocal (13)C NMR assignment of the brominated carbons at positions C-2 and C-4 of the cyclohexadiene ring, two carbons whose resonances are often incorrectly assigned. Carbon 73-80 complement C2 Homo sapiens 94-97 22961686-2 2012 Here we report on the unequivocal (13)C NMR assignment of the brominated carbons at positions C-2 and C-4 of the cyclohexadiene ring, two carbons whose resonances are often incorrectly assigned. Carbon 73-80 complement C4A (Rodgers blood group) Homo sapiens 102-105 22961686-2 2012 Here we report on the unequivocal (13)C NMR assignment of the brominated carbons at positions C-2 and C-4 of the cyclohexadiene ring, two carbons whose resonances are often incorrectly assigned. Carbon 138-145 complement C2 Homo sapiens 94-97 22961686-2 2012 Here we report on the unequivocal (13)C NMR assignment of the brominated carbons at positions C-2 and C-4 of the cyclohexadiene ring, two carbons whose resonances are often incorrectly assigned. Carbon 138-145 complement C4A (Rodgers blood group) Homo sapiens 102-105 22825489-3 2012 In this perspective, the information available from kinetico-mechanistic studies of cyclometalation reactions on Pd(II) and Rh(II) centres via C-H bond activation is considered. Carbon 143-144 Rh blood group D antigen Homo sapiens 124-130 22886082-5 2012 The observed Fe-C-O bond angle of 132 is more acute than the electronically related Fe(III), CN-LPO with a Fe-C-N angle of 161 . Carbon 94-95 lactoperoxidase Bos taurus 97-100 24688771-4 2012 We injected polyinosinic:polycytidylic acid (Poly I:C) in pregnant C57Bl/6 mice to stimulate an anti-viral response through TLR3 and examined gene expressions in the neuronal progenitor cells (NPCs) of the offspring at different ages. Carbon 52-53 toll-like receptor 3 Mus musculus 124-128 22531767-3 2012 The carbon preference index (CPI, based on nC24 to nC34 range), indicated predominance of petrogenic input in two of the sites analyzed (P4 and P5). Carbon 4-10 solute carrier family 10 member 4 Homo sapiens 137-146 22713915-1 2012 Carbon nanoparticles (CNPs) and halloysite nanoclay (HNC) modified carbon paste electrode (HNC-CNP-CPE) was developed for the determination of methyl parathion (MP) and ethyl parathion (EP). Carbon 67-73 carboxypeptidase E Homo sapiens 99-102 22837425-6 2012 Our current findings suggest for the first time that metformin can function as an antifolate chemotherapeutic agent that induces the ATM/AMPK tumor suppressor axis secondarily following the alteration of the carbon flow through the folate-related one-carbon metabolic pathways. Carbon 208-214 ATM serine/threonine kinase Homo sapiens 133-136 22837425-6 2012 Our current findings suggest for the first time that metformin can function as an antifolate chemotherapeutic agent that induces the ATM/AMPK tumor suppressor axis secondarily following the alteration of the carbon flow through the folate-related one-carbon metabolic pathways. Carbon 251-257 ATM serine/threonine kinase Homo sapiens 133-136 22709825-5 2012 Here, we investigate the effects of chronic ethanol on neuroinflammation and neurodegeneration triggered by toll-like receptor 3 (TLR3) agonist poly I:C. Carbon 151-152 toll-like receptor 3 Mus musculus 108-128 22709825-5 2012 Here, we investigate the effects of chronic ethanol on neuroinflammation and neurodegeneration triggered by toll-like receptor 3 (TLR3) agonist poly I:C. Carbon 151-152 toll-like receptor 3 Mus musculus 130-134 22709825-13 2012 Ethanol pretreatment potentiated poly I:C-induced brain TNFalpha (345%), IL-1beta (331%), IL-6 (255%), and MCP-1(190%). Carbon 40-41 interleukin 1 alpha Mus musculus 73-81 22514274-3 2012 In the dark oxidized CP12 forms an inactive supramolecular complex with glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and phosphoribulokinase, two enzymes of the carbon assimilation cycle. Carbon 165-171 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 21-25 22504965-5 2012 The carbon compound lin-HCN (HCN=hydrogen cyanide) is 14.9 kcal mol(-1) lower in energy than lin-HNC but the heavier group 14 homologues lin-HEN (E=Si-Pb) are between 64.8 and 71.5 kcal mol(-1) less stable than the lin-HNE isomers. Carbon 4-10 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 24-27 22504965-5 2012 The carbon compound lin-HCN (HCN=hydrogen cyanide) is 14.9 kcal mol(-1) lower in energy than lin-HNC but the heavier group 14 homologues lin-HEN (E=Si-Pb) are between 64.8 and 71.5 kcal mol(-1) less stable than the lin-HNE isomers. Carbon 4-10 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 29-32 22585588-5 2012 The results of our enzymatic assays performed on substrates presenting different carbon chain lengths (octanoyl-CoA and palmitoyl-CoA) are compatible with the hypothesis of a differential regulation of the ACOX1 isoforms by diesel and biodiesels. Carbon 81-87 acyl-CoA oxidase 1 Rattus norvegicus 206-211 22525679-0 2012 GABA induction of the Saccharomyces cerevisiae UGA4 gene depends on the quality of the carbon source: role of the key transcription factors acting in this process. Carbon 87-93 Uga4p Saccharomyces cerevisiae S288C 47-51 22525679-4 2012 The quality of the carbon source modulates UGA4 expression through two parallel pathways, each one acting on different regulatory elements, the UAS(GATA) and the UAS(GABA). Carbon 19-25 Uga4p Saccharomyces cerevisiae S288C 43-47 22497458-3 2012 The reaction is initiated by a barrierless addition of the phenyl radical to the terminal carbon atom of the 1,3-butadiene (C1/C4) to form a bound intermediate; the latter underwent hydrogen elimination from the terminal CH(2) group of the 1,3-butadiene molecule leading to 1-phenyl-trans-1,3-butadiene through a submerged barrier. Carbon 90-96 heterogeneous nuclear ribonucleoprotein C Homo sapiens 124-129 22351292-5 2012 The metastable process that creates the most prevalent peak is shown to be C(5)H(5)N(+) C(4)H(4)(+) + HCN. Carbon 75-76 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 104-107 22358110-1 2012 Based on an ab initio evolutionary algorithm, a novel carbon polymorph with an orthorhombic Cmcm symmetry is predicted, named as C carbon, which has the lowest enthalpy among the previously proposed cold-compressed graphite phases. Carbon 54-60 steroid sulfatase Homo sapiens 126-130 22358110-1 2012 Based on an ab initio evolutionary algorithm, a novel carbon polymorph with an orthorhombic Cmcm symmetry is predicted, named as C carbon, which has the lowest enthalpy among the previously proposed cold-compressed graphite phases. Carbon 131-137 steroid sulfatase Homo sapiens 126-130 22472516-4 2012 In Arabidopsis, overexpression of purple acid phosphatase 2 encoded by Arabidopsis (AtPAP2) promotes plant growth by modulating carbon metabolism. Carbon 128-134 Purple acid phosphatases superfamily protein Arabidopsis thaliana 34-59 22472516-4 2012 In Arabidopsis, overexpression of purple acid phosphatase 2 encoded by Arabidopsis (AtPAP2) promotes plant growth by modulating carbon metabolism. Carbon 128-134 Purple acid phosphatases superfamily protein Arabidopsis thaliana 84-90 22317835-3 2012 In this work, a highly sensitive biosensor for sequence specific miRNA-21 detection without miRNA-21 labeling and enrichment was constructed based on the substrate electrode of dendritic gold nanostructure (DenAu) and graphene nanosheets modified glassy carbon electrode. Carbon 254-260 microRNA 21 Homo sapiens 65-73 22313416-0 2012 Me3(OMe)tBuXPhos: a surrogate ligand for Me4tBuXPhos in palladium-catalyzed C-N and C-O bond-forming reactions. Carbon 76-77 protocadherin beta 17 pseudogene Homo sapiens 41-44 22344440-4 2012 We report on the conversion of synthesis gas to C(2) through C(4) olefins with selectivity up to 60 weight percent, using catalysts that constitute iron nanoparticles (promoted by sulfur plus sodium) homogeneously dispersed on weakly interactive alpha-alumina or carbon nanofiber supports. Carbon 263-269 complement C2 Homo sapiens 48-52 22344440-4 2012 We report on the conversion of synthesis gas to C(2) through C(4) olefins with selectivity up to 60 weight percent, using catalysts that constitute iron nanoparticles (promoted by sulfur plus sodium) homogeneously dispersed on weakly interactive alpha-alumina or carbon nanofiber supports. Carbon 263-269 complement C4A (Rodgers blood group) Homo sapiens 61-65 22296835-3 2012 Posttranslational activation of yPASK, either by cell integrity stress or by growth on nonfermentative carbon sources, also suppressed the growth defect resulting from tor2 mutation. Carbon 103-109 phosphatidylinositol kinase-related protein kinase TOR2 Saccharomyces cerevisiae S288C 168-172 22366772-5 2012 The ability to transport ingested vitamin C from the intestines into blood is limited by the saturable sodium-dependent vitamin C transporter (SVCT1) and thus very high intakes and the use of supplements are often erroneously considered to be of greater benefit that they really are. Carbon 42-43 solute carrier family 23 member 1 Homo sapiens 143-148 22301961-1 2012 The Arabidopsis EXORDIUM-LIKE1 (EXL1) gene (At1g35140) is required for adaptation to carbon (C)- and energy-limiting growth conditions. Carbon 85-95 Phosphate-responsive 1 family protein Arabidopsis thaliana 16-30 22301961-1 2012 The Arabidopsis EXORDIUM-LIKE1 (EXL1) gene (At1g35140) is required for adaptation to carbon (C)- and energy-limiting growth conditions. Carbon 85-95 Phosphate-responsive 1 family protein Arabidopsis thaliana 32-36 19211970-8 2008 Caffeine may be applied as a marker substance for assessing the activity of CYP1A2 in human and rat liver, but by using different reactions: 3-N-demethylation in humans and C-8-hydroxylation in rats. Carbon 0-1 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 76-82 18321643-0 2008 Removal of aluminum from aqueous solutions by adsorption on date-pit and BDH activated carbons. Carbon 87-94 3-hydroxybutyrate dehydrogenase 1 Homo sapiens 73-76 18321643-1 2008 The use of a locally prepared date-pit activated carbon and the commercially available BDH activated carbon for the removal of trivalent aluminum from aqueous solutions was examined at various conditions. Carbon 101-107 3-hydroxybutyrate dehydrogenase 1 Homo sapiens 87-90 18321643-5 2008 However, the BDH activated carbon was more effective in adsorbing aluminum with high concentrations and low pH. Carbon 27-33 3-hydroxybutyrate dehydrogenase 1 Homo sapiens 13-16 18586770-3 2008 In the inactivation, the Co-C bond of adenosylcobalamin underwent irreversible cleavage forming unidentified radicals and cob(II)alamin that resisted oxidation even in the presence of oxygen. Carbon 25-26 metabolism of cobalamin associated B Homo sapiens 46-49 18550892-0 2008 Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro- or anti-apoptotic signaling in primary neurons. Carbon 26-32 PCNA clamp associated factor Homo sapiens 42-68 18621412-7 2008 Over large catchments, half-life times were important in terms of global loss from the agricultural lands to wetlands whereas over small catchments, soil organic carbon/water distribution coefficient (Koc) was an important term for pesticides losses to water system since half-life times were not limiting factors. Carbon 162-168 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 201-204 18665600-3 2008 When the temperature is increased and H approaches, the H-CO 2 complex flips and binds to the surface through the two oxygen atoms, while H binds to the carbon atom, thus yielding formate. Carbon 153-159 complement C2 Homo sapiens 58-62 18630902-6 2008 Finally, [(CH 3) 3C{ClGa(DDP)}] ( 6) is synthesized by insertion of Ga(DDP) into the C-Cl bond of ClC(CH 3) 3. Carbon 11-12 translocase of inner mitochondrial membrane 8A Homo sapiens 25-28 18630902-6 2008 Finally, [(CH 3) 3C{ClGa(DDP)}] ( 6) is synthesized by insertion of Ga(DDP) into the C-Cl bond of ClC(CH 3) 3. Carbon 11-12 translocase of inner mitochondrial membrane 8A Homo sapiens 22-29 18605717-6 2008 Pharmacological studies showed that (-)-6c is an alpha4beta2-nAChR antagonist with low side effects in mice. Carbon 36-42 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus 61-66 18670171-0 2008 Re: Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. Carbon 91-97 transformation related protein 53, pseudogene Mus musculus 33-36 18670173-0 2008 Re: Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. Carbon 91-97 transformation related protein 53, pseudogene Mus musculus 33-36 18582021-8 2008 MP2 calculations of valence interaction force constants involving the stretching of bonds on a common carbon atom are preferred to those from a B3LYP model. Carbon 102-108 tryptase pseudogene 1 Homo sapiens 0-3 18479727-1 2008 Even though it is well established that soil C content is the primary determinant of the sorption affinity of soils for non-ionic compounds, it is also clear that organic carbon-normalized sorption coefficients (K(OC)) vary considerably between soils. Carbon 171-177 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 212-217 18300290-7 2008 Furthermore, a subset with a large N/C ratio expressing high levels of p63 was observed, as much as 25% among the limbal basal cell fraction, in contrast to only about 4% in the total limbal epithelial cells. Carbon 37-38 tumor protein p63 Homo sapiens 71-74 18414997-4 2008 MS increased carbon incorporation of KIC into acid-precipitable material and lipid in INS-1 cells. Carbon 13-19 insulin 1 Rattus norvegicus 86-91 18572648-7 2008 The reduced levels of complement activation via the classical pathway, that are likely to increase biocompatibility, were directly correlated with the amount of C1q protein bound to chemically modified carbon nanotubes. Carbon 202-208 complement C1q A chain Homo sapiens 161-164 18285342-9 2008 Based on the pattern of apocarotenoid volatiles produced, we propose that CCD1 recognizes its cleavage site based on the saturation status between carbons 7 and 8 (7" and 8") and carbons 11 and 12 (11" and 12") as well as the methyl groups on carbons 5, 9, and 13 (5", 9", and 13"). Carbon 147-154 white cap1 Zea mays 74-78 18285342-9 2008 Based on the pattern of apocarotenoid volatiles produced, we propose that CCD1 recognizes its cleavage site based on the saturation status between carbons 7 and 8 (7" and 8") and carbons 11 and 12 (11" and 12") as well as the methyl groups on carbons 5, 9, and 13 (5", 9", and 13"). Carbon 179-186 white cap1 Zea mays 74-78 18285342-9 2008 Based on the pattern of apocarotenoid volatiles produced, we propose that CCD1 recognizes its cleavage site based on the saturation status between carbons 7 and 8 (7" and 8") and carbons 11 and 12 (11" and 12") as well as the methyl groups on carbons 5, 9, and 13 (5", 9", and 13"). Carbon 179-186 white cap1 Zea mays 74-78 18243488-2 2008 This work reports the presentation of myoglobin/nickel oxide nanoparticles/glassy carbon (Mb/NiO NPs/GC) electrode, ready by electrochemical deposition of the NiO NPs on glassy carbon electrode and myoglobin immobilization on their surfaces by the potential cycling method. Carbon 82-88 myoglobin Homo sapiens 198-207 18243488-2 2008 This work reports the presentation of myoglobin/nickel oxide nanoparticles/glassy carbon (Mb/NiO NPs/GC) electrode, ready by electrochemical deposition of the NiO NPs on glassy carbon electrode and myoglobin immobilization on their surfaces by the potential cycling method. Carbon 177-183 myoglobin Homo sapiens 38-47 18245858-5 2008 atg10-1 plants are hypersensitive to nitrogen and carbon starvation and initiate senescence and programmed cell death (PCD) more quickly than wild type, as indicated by elevated levels of senescence- and PCD-related mRNAs and proteins during carbon starvation. Carbon 50-56 meiotically up-regulated protein Arabidopsis thaliana 0-7 18245858-5 2008 atg10-1 plants are hypersensitive to nitrogen and carbon starvation and initiate senescence and programmed cell death (PCD) more quickly than wild type, as indicated by elevated levels of senescence- and PCD-related mRNAs and proteins during carbon starvation. Carbon 242-248 meiotically up-regulated protein Arabidopsis thaliana 0-7 18298799-5 2008 Here, we have shown that cytoplasmic PML (cPML) directly interacts with M2-type pyruvate kinase (PKM2), a key regulator of carbon fate. Carbon 123-129 PML nuclear body scaffold Homo sapiens 37-40 18298799-5 2008 Here, we have shown that cytoplasmic PML (cPML) directly interacts with M2-type pyruvate kinase (PKM2), a key regulator of carbon fate. Carbon 123-129 pyruvate kinase M1/2 Homo sapiens 97-101 18298799-6 2008 PKM2 determines the proportion of carbons derived from glucose that are used for glycolytic energy production. Carbon 34-41 pyruvate kinase M1/2 Homo sapiens 0-4 18031540-6 2008 Principal component analysis and confirmatory correlation analysis of individual variables showed that high abundances of VLP occurred in lakes of high conductivity with high concentrations of soluble reactive phosphorus and dissolved organic carbon. Carbon 243-249 VHL like Homo sapiens 122-125 18941292-1 2008 Some synthetically useful transformations of organosilicon compounds have been developed since the mid 1970s, based on the new concept that the silicon-carbon bonds are activated toward electrophilic cleavage via the formation of penta- and hexa-coordinate species. Carbon 152-158 hexosaminidase subunit alpha Homo sapiens 241-245 18776629-1 2008 Using succinonitrile as a sole source of carbon and nitrogen, two bacterium strains named as J-1-3 and J-13-1 were isolated and screened out from the treatment facilities of Shanghai petrochemical wastewater treatment plant treating acrylic fiber production wastewater. Carbon 41-47 immunoglobulin kappa joining 1 Homo sapiens 93-98 23028504-6 2012 The molecular model of 1, which mimics the l-Ser-l-Pro stereochemistry, in the Pin1 active site showed a distance of 4.4 A, and an angle of 31 between Cys113-S and the ketone carbon. Carbon 176-182 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens 79-83 34045854-2 2021 Here, we present an electrochemical biosensor for PML/RARalpha fusion gene detection using carbon dots functionalized graphene oxide (CDs/GO) nanocomposites modified glassy carbon electrode (CDs/GO/GCE). Carbon 91-97 retinoic acid receptor alpha Homo sapiens 54-62 18804700-1 2008 In mammals, folate is used as a carrier of one-carbon units (C(1)) in nucleic acids metabolism and biological methylation. Carbon 47-53 heterogeneous nuclear ribonucleoprotein C Homo sapiens 61-65 22319575-11 2012 Consistent with this finding, administration of poly(I:C) to TG2 knockout mice also induced villous atrophy. Carbon 0-1 transglutaminase 2, C polypeptide Mus musculus 61-64 34045854-2 2021 Here, we present an electrochemical biosensor for PML/RARalpha fusion gene detection using carbon dots functionalized graphene oxide (CDs/GO) nanocomposites modified glassy carbon electrode (CDs/GO/GCE). Carbon 173-179 PML nuclear body scaffold Homo sapiens 50-53 18371657-1 2007 The construction of a colloidal gold-cysteamine-carbon paste electrode, Au(coll)-Cyst-CPE, for the electrochemical determination of homocysteine is reported. Carbon 48-54 carboxypeptidase E Homo sapiens 86-89 34045854-2 2021 Here, we present an electrochemical biosensor for PML/RARalpha fusion gene detection using carbon dots functionalized graphene oxide (CDs/GO) nanocomposites modified glassy carbon electrode (CDs/GO/GCE). Carbon 173-179 retinoic acid receptor alpha Homo sapiens 54-62 34002739-4 2021 Prussian blue (PB) was electrochemically deposited on the surface of a glassy carbon electrode (GCE). Carbon 78-84 aminomethyltransferase Homo sapiens 96-99 17891500-10 2007 In conclusion, the results of this study suggest that genetic polymorphisms of one-carbon metabolism genes such as MTHFR and TYMS may influence susceptibility to NHL. Carbon 83-89 thymidylate synthetase Homo sapiens 125-129 17989693-5 2007 These pathways differentially activate the two PAS kinase proteins in Saccharomyces cerevisiae, Psk1 and Psk2, with Psk1 alone responding to activation by nonfermentative carbon sources. Carbon 171-177 serine/threonine protein kinase PSK2 Saccharomyces cerevisiae S288C 105-109 22119036-2 2012 INCA-C, the Integrated Catchment model for Carbon, incorporates carbon biogeochemical processes in a terrestrial system with hydrologic flow paths to simulate watershed wide [DOC]. Carbon 43-49 caspase recruitment domain family member 17 Homo sapiens 0-4 22119036-2 2012 INCA-C, the Integrated Catchment model for Carbon, incorporates carbon biogeochemical processes in a terrestrial system with hydrologic flow paths to simulate watershed wide [DOC]. Carbon 64-70 caspase recruitment domain family member 17 Homo sapiens 0-4 22119036-7 2012 INCA-C also predicts possible increases in dissolved inorganic carbon in some tributaries with rising temperature suggesting increased CO(2) emissions from rivers as climate changes. Carbon 63-69 caspase recruitment domain family member 17 Homo sapiens 0-4 33908967-2 2021 In this study, we have used Vulcan carbon as a conductive additive to formulate LiNi1/3Co1/3Mn1/3O2 (NCM) based slurries as the catholyte to characterize electrical and electrochemical performances using a 3-electrode flow cell by electrochemical impedance spectroscopy (EIS) and galvanostatic charge/discharge (GCD), respectively. Carbon 35-41 CWC22 spliceosome associated protein homolog Homo sapiens 101-104 22409043-0 2011 Toxicity of carbon nanotubes to p21 and hus1 gene deficient mammalian cells. Carbon 12-18 H3 histone pseudogene 16 Homo sapiens 32-35 22409043-0 2011 Toxicity of carbon nanotubes to p21 and hus1 gene deficient mammalian cells. Carbon 12-18 HUS1 checkpoint clamp component Homo sapiens 40-44 22409043-3 2011 The aim of this study is to investigate the role of the p21 and hus1 genes in the toxicity of carbon nanotubes. Carbon 94-100 H3 histone pseudogene 16 Homo sapiens 56-59 22409043-3 2011 The aim of this study is to investigate the role of the p21 and hus1 genes in the toxicity of carbon nanotubes. Carbon 94-100 HUS1 checkpoint clamp component Homo sapiens 64-68 22409043-5 2011 Our results show that the yield of the micronucleus ratio in p21 gene knock-out MEF cells is lower than that in the wild type counterpart, indicating that p21 may play as anti-apoptosis factor during the signal transduction of DNA damage caused by carbon nanotubes in mammalian cells. Carbon 248-254 H3 histone pseudogene 16 Homo sapiens 61-64 22409043-5 2011 Our results show that the yield of the micronucleus ratio in p21 gene knock-out MEF cells is lower than that in the wild type counterpart, indicating that p21 may play as anti-apoptosis factor during the signal transduction of DNA damage caused by carbon nanotubes in mammalian cells. Carbon 248-254 H3 histone pseudogene 16 Homo sapiens 155-158 17937387-5 2007 A real-time polymerase chain reaction analysis of 10 genes in the one-carbon metabolism pathway revealed that 5,10-methylenetetrahydrofolate reductase, S-adenosylhomocysteine hydrolase (Ahcy), and formiminotransferase cyclodeaminase (Ftcd) were significantly down-regulated in Gnmt-/- mice. Carbon 70-76 S-adenosylhomocysteine hydrolase Mus musculus 152-184 17937387-5 2007 A real-time polymerase chain reaction analysis of 10 genes in the one-carbon metabolism pathway revealed that 5,10-methylenetetrahydrofolate reductase, S-adenosylhomocysteine hydrolase (Ahcy), and formiminotransferase cyclodeaminase (Ftcd) were significantly down-regulated in Gnmt-/- mice. Carbon 70-76 S-adenosylhomocysteine hydrolase Mus musculus 186-190 18154030-3 2007 In an inhibition assay of carbon particle phagocytosis as a representation of natural phagocytosis, neutrophils binding with TAG3 or TAG4 were inhibited from carbon particle-phagocytosis by 42.5% and 53.2% (% inhibition), respectively, but in an inhibition assay using TAG3 MoAb, HNA-2a strongly positive neutrophils were more weakly inhibited than HNA-2a weak-positive neutrophils, 39.2% and 54.0% (% inhibition), respectively. Carbon 158-164 CD177 molecule Homo sapiens 280-286 18154030-3 2007 In an inhibition assay of carbon particle phagocytosis as a representation of natural phagocytosis, neutrophils binding with TAG3 or TAG4 were inhibited from carbon particle-phagocytosis by 42.5% and 53.2% (% inhibition), respectively, but in an inhibition assay using TAG3 MoAb, HNA-2a strongly positive neutrophils were more weakly inhibited than HNA-2a weak-positive neutrophils, 39.2% and 54.0% (% inhibition), respectively. Carbon 158-164 CD177 molecule Homo sapiens 349-355 21962860-3 2011 The adsorption and desorption performance of benzene on carbon-silica aerogel composite (CSA-2) under static and dynamic conditions were investigated, comparing with pure silica aerogel (CSA-0) and microporous activated carbon (AC). Carbon 56-62 IK cytokine Homo sapiens 89-94 34051467-2 2021 To achieve this goal, we have developed a bifunctional nanowire-structured FeP-CoP array catalyst on carbon cloth with uniform distribution through in-situ hydrothermal growth and phosphating treatment. Carbon 101-107 caspase recruitment domain family member 16 Homo sapiens 79-82 21962860-5 2011 Excellent performance of dynamic adsorption and desorption observed on CSA-2 is related to its higher adsorption capacity than CSA-0 and less mass transfer resistance than AC, arising from the well-developed microporosity and open foam mesostructure in the CSA composites. Carbon 172-174 IK cytokine Homo sapiens 71-76 17316367-3 2007 Hence, Pyc1p-deficient cells share aspartate auxotrophy (Asp-) with a defect in growth on methanol as sole carbon source (Mut-). Carbon 107-113 pyruvate carboxylase 1 Saccharomyces cerevisiae S288C 7-12 33736232-7 2021 The highly agricultural river network acted as significant CO2 and CH4 sources with estimated emission fluxes of 409 +- 369 mmol m-2 d-1 for CO2 and 1.6 +- 1.2 mmol m-2 d-1 for CH4, and made a disproportionately large, relative to the area, contribution to the total aquatic carbon emission of the watershed. Carbon 275-281 complement C2 Homo sapiens 141-152 17705520-2 2007 In this method, monolayer patterns of the single-walled carbon nanotube (swCNT) network were prepared via the self-limiting mechanism during the directed assembly process, and they were used to block the adsorption of both myosin and actin filaments on specific substrate regions. Carbon 56-62 myosin heavy chain 14 Homo sapiens 223-229 22247571-1 2011 N-Heterocyclic carbene (NHC)-mediated ring-opening polymerization of N-decylN-carboxylanhydride monomer (De-NCA) has been shown to occur in a controlled manner, yielding cyclic poly(N-decyl-glycine)s (c-PNDGs) with polymer molecular weights (MW) between 4.8 and 31 kg mol(-1) and narrow molecular weight distributions (PDI < 1.15). Carbon 8-9 CEA cell adhesion molecule 6 Homo sapiens 108-111 20301763-0 1993 Very Long-Chain Acyl-Coenzyme A Dehydrogenase Deficiency CLINICAL CHARACTERISTICS: Deficiency of very long-chain acyl-CoA dehydrogenase (VLCAD), which catalyzes the initial step of mitochondrial beta-oxidation of long-chain fatty acids with a chain length of 14 to 20 carbons, is associated with three phenotypes. Carbon 268-275 acyl-CoA dehydrogenase very long chain Homo sapiens 137-142 21204862-1 2011 Sea-surface warming, sea-ice melting and related freshening, changes in circulation and mixing regimes, and ocean acidification induced by the present climate changes are modifying marine ecosystem structure and function and have the potential to alter the cycling of carbon and nutrients in surface oceans. Carbon 268-274 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 0-3 21921115-1 2011 In seeds, glutamate decarboxylase (GAD) operates at the metabolic nexus between carbon and nitrogen metabolism by catalyzing the unidirectional decarboxylation of glutamate to form gamma-aminobutyric acid (GABA). Carbon 80-86 glutamate decarboxylase Arabidopsis thaliana 10-33 21921115-1 2011 In seeds, glutamate decarboxylase (GAD) operates at the metabolic nexus between carbon and nitrogen metabolism by catalyzing the unidirectional decarboxylation of glutamate to form gamma-aminobutyric acid (GABA). Carbon 80-86 glutamate decarboxylase Arabidopsis thaliana 35-38 21921115-10 2011 Taken together, these results indicate that the GAD-mediated conversion of glutamate to GABA during seed development plays an important role in balancing carbon and nitrogen metabolism and in storage reserve accumulation. Carbon 154-160 glutamate decarboxylase Arabidopsis thaliana 48-51 21989811-7 2011 In addition to the two required protein kinases, our results implicate that Stm1p, a ribosome-associated protein involved in nutrient sensing, is essential for the carbon source-dependent regulation of Ty3 frameshifting. Carbon 164-170 Stm1p Saccharomyces cerevisiae S288C 76-81 21872983-1 2011 A combined reaction, consisting of granular activated carbon (GAC) adsorption and catalytic oxidation, has been proposed to improve the removal efficiencies of formaldehyde, one of the major indoor air pollutants. Carbon 54-60 glutaminase Homo sapiens 62-65 21871723-1 2011 This study investigated the effects of in situ ZrO(2) nanoparticle formation on properties of granulated activated carbon (GAC) and their impacts on arsenic and organic co-contaminant removal. Carbon 115-121 glutaminase Homo sapiens 123-126 21962705-1 2011 A new procedure was elaborated to determine mercury(II) using an anodic stripping square-wave voltammetry at the antimony film carbon paste electrode (SbF-CPE). Carbon 127-133 carboxypeptidase E Homo sapiens 155-158 21598384-0 2011 Fluorescence derivatization of single-walled carbon nanotubes for analysis by means of conventional CE-LIF. Carbon 45-51 LIF interleukin 6 family cytokine Homo sapiens 103-106 22024880-2 2011 Here, we use molecular dynamics simulations to model the vibrational relaxation that occurs during the reaction CN + c-C(6)H(12) HCN + c-C(6)H(11) in CH(2)Cl(2), which produces vibrationally hot HCN. Carbon 17-18 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 131-134 21799342-5 2011 These data demonstrate that indirect interactions between breast cancer cells and MC3T3-E1 cells induce osteoclastogenesis in vitro through modulation of RANKL expression and that this process is suppressed by carbon ion irradiation. Carbon 210-216 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 154-159 22276430-7 2011 Moreover, both the point gsh1 and null gsh1/met1 mutants displayed increased sensitivity to the toxic carbon substrate methanol, formaldehyde, organic peroxide and cadmium ions. Carbon 102-108 uroporphyrinogen-III C-methyltransferase Saccharomyces cerevisiae S288C 44-48 21749092-0 2011 A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis. Carbon 47-53 glutathione S-transferase kappa 1 Homo sapiens 12-37 21777907-6 2011 In the present work, a putative interaction between NPY, the catecholaminergic and serotonergic systems has been analysed by means of in vivo Differential Pulse Voltammetry (DPV) with treated carbon fibre micro electrodes (mCFE). Carbon 192-198 neuropeptide Y Homo sapiens 52-55 21793061-5 2011 This reduced electrostatic interaction, and the large interfragment dispersion stabilize the long, heterocationic/anionic multicenter interaction, which in [TTF(delta+) TCNE(delta-)] always involves two electrons, but have ten, eight, and eight bond critical points (bcps) involving C-C, N-S, and sometimes C-S and C-N components for the alpha, beta, and delta polymorphs, respectively. Carbon 172-173 ras homolog family member H Homo sapiens 157-160 21793061-5 2011 This reduced electrostatic interaction, and the large interfragment dispersion stabilize the long, heterocationic/anionic multicenter interaction, which in [TTF(delta+) TCNE(delta-)] always involves two electrons, but have ten, eight, and eight bond critical points (bcps) involving C-C, N-S, and sometimes C-S and C-N components for the alpha, beta, and delta polymorphs, respectively. Carbon 285-286 ras homolog family member H Homo sapiens 157-160 21793061-5 2011 This reduced electrostatic interaction, and the large interfragment dispersion stabilize the long, heterocationic/anionic multicenter interaction, which in [TTF(delta+) TCNE(delta-)] always involves two electrons, but have ten, eight, and eight bond critical points (bcps) involving C-C, N-S, and sometimes C-S and C-N components for the alpha, beta, and delta polymorphs, respectively. Carbon 285-286 ras homolog family member H Homo sapiens 157-160 21302143-4 2011 Culture conditions were optimized, and the highest lipase production was observed in basal medium with corn steep liquor as nitrogen source and glucose as carbon source. Carbon 155-161 lipase Zea mays 51-57 22619938-8 2011 Using SMARTS2 spectral irradiance model to estimate CO production, the photoproduction rate of CO was 54.60 micromol x (m2 x d)(-1) and the photoproduction of carbon in the Yellow Sea and the Bohai Sea was 26.95 x 10(9) g in spring. Carbon 159-165 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 180-183 22619938-8 2011 Using SMARTS2 spectral irradiance model to estimate CO production, the photoproduction rate of CO was 54.60 micromol x (m2 x d)(-1) and the photoproduction of carbon in the Yellow Sea and the Bohai Sea was 26.95 x 10(9) g in spring. Carbon 159-165 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 198-201 21887646-10 2011 An additional five CLA isomers also contained carbons originating from linoleic acid, indicating that pathways of linoleic acid biohydrogenation are more complex than previously described. Carbon 46-53 selectin P ligand Homo sapiens 19-22 21645672-2 2011 The as-prepared PB-graphene modified glassy carbon electrode (PB-graphene/GCE) showed excellent electrocatalytic activity towards both the reduction of hydrogen peroxide and the oxidation of hydrazine, which could be attributed to the remarkable synergistic effect of graphene and PB. Carbon 44-50 aminomethyltransferase Homo sapiens 74-77 21672523-4 2011 Here we show through CD and recently developed carbon-detected NMR that, although FCP1 is intrinsically disordered, the above 16 residues composing the RAP74 binding surface form nascent alpha-helical structure in the unbound state. Carbon 47-53 general transcription factor IIF subunit 1 Homo sapiens 152-157 21543728-0 2011 EXORDIUM-LIKE1 promotes growth during low carbon availability in Arabidopsis. Carbon 42-48 Phosphate-responsive 1 family protein Arabidopsis thaliana 0-14 17596206-2 2007 Functional polymorphisms in genes encoding one-carbon metabolism enzymes, such as methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), methionine synthase (MTR A2756G), methionine synthase reductase (MTRR A66G) and thymidylate synthase (TS), influence folate metabolism and thus might impact on HNSCC risk. Carbon 47-53 thymidylate synthetase Homo sapiens 224-244 17462705-8 2007 Diesel and n-hexane soot samples exhibit similar EC2 (700 degrees C in a 98% He/2% O2 atmosphere) peaks, while carbon black samples peaks at both EC2 and EC3 (800 degrees C in a 98% He/2% O2 atmosphere). Carbon 111-117 transcription factor 15 Homo sapiens 146-149 17700259-10 2007 The carbon ions had a stronger effect on p53 and p21 expression than the gamma-ray irradiation. Carbon 4-10 H3 histone pseudogene 16 Homo sapiens 49-52 17693318-1 2007 A biosensing system based on alpha-glucosidase (AG) activity was developed by using bismuth film modified glassy carbon electrode (BiFE). Carbon 113-119 sucrase-isomaltase Homo sapiens 29-46 17693318-1 2007 A biosensing system based on alpha-glucosidase (AG) activity was developed by using bismuth film modified glassy carbon electrode (BiFE). Carbon 113-119 sucrase-isomaltase Homo sapiens 48-50 18048020-4 2007 CNTO2424 down-regulates poly(I:C)-induced production of IL-6, IL-8, MCP-1, RANTES, and IP-10 in human lung epithelial cells. Carbon 0-1 C-C motif chemokine ligand 2 Homo sapiens 68-73 17345139-10 2007 These results reinforce the biogeochemical role of attached bacteria in the cycling of particulate organic carbon in the NW Mediterranean Sea and the importance of diel variability in these processes. Carbon 107-113 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 138-141 17580895-2 2007 The stereoelectronic properties of the substituents at the C-3 position and their interactions with the incoming carbon nucleophiles control the diastereoselectivity of addition at the C-5 position, favoring the formation of l-ido derivatives as major products in most of the cases studied. Carbon 113-119 complement C5 Homo sapiens 185-188 17113343-2 2007 In the present work, we systematically investigate how substitution of nitrogen in a cubanoid influence deshielding of carbon and manifest in the chemical shift in NMR spectra calculated using the second order Moller-Plesset (MP2) perturbation level of theory. Carbon 119-125 tryptase pseudogene 1 Homo sapiens 226-229 17446168-8 2007 Compartmentation of the folate-dependent de novo thymidylate biosynthesis pathway in the nucleus accounts for the preferential partitioning of cSHMT-derived folate-activated one-carbon units into thymidylate biosynthesis; the efficiency of nuclear folate metabolism is likely to be modified by the cSHMT L474F polymorphism. Carbon 178-184 serine hydroxymethyltransferase 1 Homo sapiens 143-148 17446168-8 2007 Compartmentation of the folate-dependent de novo thymidylate biosynthesis pathway in the nucleus accounts for the preferential partitioning of cSHMT-derived folate-activated one-carbon units into thymidylate biosynthesis; the efficiency of nuclear folate metabolism is likely to be modified by the cSHMT L474F polymorphism. Carbon 178-184 serine hydroxymethyltransferase 1 Homo sapiens 298-303 17374501-1 2007 Very long-chain acyl-CoA dehydrogenase (VLCAD) catalyzes the first enzymatic step in the mitochondrial beta-oxidation of fatty acids 14-20 carbons in length. Carbon 139-146 acyl-CoA dehydrogenase very long chain Homo sapiens 0-38 17374501-1 2007 Very long-chain acyl-CoA dehydrogenase (VLCAD) catalyzes the first enzymatic step in the mitochondrial beta-oxidation of fatty acids 14-20 carbons in length. Carbon 139-146 acyl-CoA dehydrogenase very long chain Homo sapiens 40-45 17436274-7 2007 The cytosine/cytosine (C/C) genotype of cytochrome P450 XIB2 (CYP11B2) was associated with decreased risk at younger ages (ages 30-44 years) but an increased risk at older ages (ages 55-69 years). Carbon 23-24 cytochrome P450 family 11 subfamily B member 2 Homo sapiens 62-69 17436274-7 2007 The cytosine/cytosine (C/C) genotype of cytochrome P450 XIB2 (CYP11B2) was associated with decreased risk at younger ages (ages 30-44 years) but an increased risk at older ages (ages 55-69 years). Carbon 25-26 cytochrome P450 family 11 subfamily B member 2 Homo sapiens 62-69 17110096-0 2007 Label-free immunosensor for prostate-specific antigen based on single-walled carbon nanotube array-modified microelectrodes. Carbon 77-83 kallikrein related peptidase 3 Homo sapiens 28-53 17303418-3 2007 Analogs with the same configuration at carbon atom C-2 as in natural salvinorin A showed higher affinity to KOR than their corresponding epimers. Carbon 39-45 complement C2 Homo sapiens 51-54 17375957-4 2007 Because the preferred conformation of the diol in the formed complex is known, we are able to determine the absolute configuration of the carbon atoms in the diol subunit even in flexible tert/tert vic-diols. Carbon 138-144 telomerase reverse transcriptase Homo sapiens 193-197 17204278-0 2007 RBM band shift-evidenced dispersion mechanism of single-wall carbon nanotube bundles with NaDDBS. Carbon 61-67 RNA binding motif protein Y-linked family 2 member D, pseudogene Homo sapiens 0-3 17450937-0 2007 Effects of antisense-myc-conjugated single-walled carbon nanotubes on HL-60 cells. Carbon 50-56 MYC proto-oncogene, bHLH transcription factor Homo sapiens 21-24 17450937-2 2007 Here we report the use of single-walled carbon nanotubes as delivery system for transporting antisense myc into HL-60 cells. Carbon 40-46 MYC proto-oncogene, bHLH transcription factor Homo sapiens 103-106 17450937-3 2007 Antisense-myc-conjugated single-walled carbon nanotubes were synthesized, characterized by atomic force microscopy (AFM), fluorescent microscopy, and Raman spectroscopy. Carbon 39-45 MYC proto-oncogene, bHLH transcription factor Homo sapiens 10-13 17465211-7 2007 The DPD mRNA levels (0.295 vs. 0.381, p = 0.2460) and OPRT/DPD ratio (5.535 vs. 4.394. p = 0.226) had a weak correlation with the T/C ratio. Carbon 132-133 uridine monophosphate synthetase Homo sapiens 54-58 16716587-1 2007 The purpose of the present study was to examine the removal of ammoniacal nitrogen (NH4-N) from synthetic wastewater using limestone (LS) and granular activated carbon (GAC) mixture as low cost adsorbent. Carbon 161-167 glutaminase Homo sapiens 169-172 16915305-8 2007 Run training produced an increase in the maximal responses (E(max)) of CC for ACh (C-SD: 47+/-3; C-TR: 52+/-1; and LN-TR: 53+/-3%) and SNP (C-SD: 89+/-1; C-TR: 98+/-1; and LN-TR: 95+/-1%). Carbon 71-72 calcitonin receptor Rattus norvegicus 97-101 16915305-8 2007 Run training produced an increase in the maximal responses (E(max)) of CC for ACh (C-SD: 47+/-3; C-TR: 52+/-1; and LN-TR: 53+/-3%) and SNP (C-SD: 89+/-1; C-TR: 98+/-1; and LN-TR: 95+/-1%). Carbon 71-72 calcitonin receptor Rattus norvegicus 154-158 16915305-8 2007 Run training produced an increase in the maximal responses (E(max)) of CC for ACh (C-SD: 47+/-3; C-TR: 52+/-1; and LN-TR: 53+/-3%) and SNP (C-SD: 89+/-1; C-TR: 98+/-1; and LN-TR: 95+/-1%). Carbon 72-73 calcitonin receptor Rattus norvegicus 97-101 16915305-8 2007 Run training produced an increase in the maximal responses (E(max)) of CC for ACh (C-SD: 47+/-3; C-TR: 52+/-1; and LN-TR: 53+/-3%) and SNP (C-SD: 89+/-1; C-TR: 98+/-1; and LN-TR: 95+/-1%). Carbon 72-73 calcitonin receptor Rattus norvegicus 154-158 16944197-4 2007 Our results indicate that, in maize root tips, endopeptidase activities and protease expression are induced in response to a decrease in carbon supply to the upper part of the glycolytic pathway, i.e. at the hexokinase step. Carbon 137-143 hexokinase 2 Zea mays 208-218 17386421-0 2007 Voltammetric determination of Cd2+ based on the bifunctionality of single-walled carbon nanotubes-Nafion film. Carbon 81-87 CD2 molecule Homo sapiens 30-33 17212441-0 2007 Tip cooling effect and failure mechanism of field-emitting carbon nanotubes. Carbon 59-65 TOR signaling pathway regulator Homo sapiens 0-3 17165933-3 2006 The cis-1 addition pattern electronically activates three trans-4 C=C bonds on the opposite hemisphere of C60, allowing further highly regioselective additions at these positions. Carbon 66-67 suppressor of cytokine signaling 1 Homo sapiens 4-9 17165933-3 2006 The cis-1 addition pattern electronically activates three trans-4 C=C bonds on the opposite hemisphere of C60, allowing further highly regioselective additions at these positions. Carbon 68-69 suppressor of cytokine signaling 1 Homo sapiens 4-9 17165934-1 2006 [Structure: see text] Photocatalytic carbon-carbon bond formation of 9,10-dimethylanthracene (DMA) in chloroform occurs efficiently via the electron-transfer oxidation of DMA with the photoinduced electron-transfer state of 9-mesityl-10-methylacridinium ion (Acr+-Mes), followed by deprotonation from the methyl group of DMA radical cation and the radical coupling reaction between anthracenylmethyl radicals to produce dimethyllepidopterene. Carbon 37-43 acrosin Homo sapiens 259-262 17165934-1 2006 [Structure: see text] Photocatalytic carbon-carbon bond formation of 9,10-dimethylanthracene (DMA) in chloroform occurs efficiently via the electron-transfer oxidation of DMA with the photoinduced electron-transfer state of 9-mesityl-10-methylacridinium ion (Acr+-Mes), followed by deprotonation from the methyl group of DMA radical cation and the radical coupling reaction between anthracenylmethyl radicals to produce dimethyllepidopterene. Carbon 44-50 acrosin Homo sapiens 259-262 17007889-5 2006 DPSA revealed that polyunsaturated fatty acids of 18 to 20 carbon groups with 3-5 double bonds strongly induced a PPARalpha conformational change. Carbon 59-65 peroxisome proliferator activated receptor alpha Homo sapiens 114-123 21537513-1 2011 Based on the structures of natural sphingolipids, we designed heterocyclic sphingoid base mimetics in which the conformational restriction is introduced by incorporation of a pyrrolidine moiety between the 2-amino group and the C-4 carbon atom of the sphingoid base. Carbon 232-238 complement C4A (Rodgers blood group) Homo sapiens 228-231 21469113-6 2011 Furthermore, in zymosan- and polyI:C-stimulated macrophages, Cot/tpl2 mediates P-Ser473 Akt phosphorylation, increases IkappaBalpha levels and decreases NOS2 expression. Carbon 35-36 mitogen-activated protein kinase kinase kinase 8 Homo sapiens 61-69 33980540-0 2021 Government should commit to making GP premises carbon neutral by 2030, say leaders. Carbon 47-53 ring finger protein 130 Homo sapiens 35-37 21422176-8 2011 Catabolome analysis with Biolog GN2 microplates revealed an enhanced ability of both E. coli MG1655* and the isogenic flhD mutant to oxidize a variety of carbon sources. Carbon 154-160 DNA-binding transcriptional dual regulator FlhD Escherichia coli str. K-12 substr. MG1655 118-122 17129061-1 2006 We report herein the electrochemical dehalogenation of vicinal dibromides in microemulsions using cross-linked films of the redox protein myoglobin (Mb) and poly-l-lysine (PLL) covalently bonded to carbon electrodes. Carbon 198-204 myoglobin Homo sapiens 138-147 17129061-1 2006 We report herein the electrochemical dehalogenation of vicinal dibromides in microemulsions using cross-linked films of the redox protein myoglobin (Mb) and poly-l-lysine (PLL) covalently bonded to carbon electrodes. Carbon 198-204 myoglobin Homo sapiens 149-151 21422176-9 2011 The results show that intestine-adapted E. coli MG1655* is more fit than the wild type for intestinal colonization, because loss of FlhD results in elevated expression of genes involved in carbon and energy metabolism, resulting in more efficient carbon source utilization and a higher intestinal population. Carbon 189-195 DNA-binding transcriptional dual regulator FlhD Escherichia coli str. K-12 substr. MG1655 132-136 34055781-11 2021 (2) DL-Norvaline, a product of carbon metabolism in cells, inhibited autophagy in A549 cells under low-dose radiation. Carbon 31-37 autophagy and beclin 1 regulator 1 Homo sapiens 69-78 21422176-9 2011 The results show that intestine-adapted E. coli MG1655* is more fit than the wild type for intestinal colonization, because loss of FlhD results in elevated expression of genes involved in carbon and energy metabolism, resulting in more efficient carbon source utilization and a higher intestinal population. Carbon 247-253 DNA-binding transcriptional dual regulator FlhD Escherichia coli str. K-12 substr. MG1655 132-136 17009365-4 2006 Because the second carbon center is also nucleophilic, cumulene E1 reacts as a "pincer" with BF(3)OEt(2), leading to the formation of a novel four-membered PCBC heterocycle 6 with a betaine-like structure. Carbon 19-25 EPH receptor B2 Homo sapiens 156-160 34055781-15 2021 Autophagy interacts with the cellular carbon metabolite DL-Norvaline to participate in regulating the low-dose radiosensitivity of cells. Carbon 38-44 autophagy and beclin 1 regulator 1 Homo sapiens 0-9 33682282-9 2021 We show that the N-doped carbon material derived from ZIF-EC1 is a promising electrocatalysis for oxygen reduction reaction (ORR). Carbon 25-31 Susceptibility to lysis by alloreactive natural killer cells Homo sapiens 58-61 17154008-1 2006 A new model to estimate the soil-water partition coefficient of non-ionic organic compounds normalized to soil organic carbon, Koc, from the two-dimensional molecular structure is presented. Carbon 119-125 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 127-130 21462919-6 2011 Simultaneous real time BChE activity was measured on an electrochemical carbon nanotube-based sensor coupled with a microflow injection system after immunocapture by the MB-anti-BChE conjugate. Carbon 72-78 butyrylcholinesterase Homo sapiens 23-27 33342622-9 2021 DISCUSSION: Pediatric providers should be familiar with diagnosis, treatment, and management of FH to successfully lower LDL-C levels and avoid potential long-term health effects. Carbon 124-126 low density lipoprotein receptor Homo sapiens 96-98 21500305-6 2011 Consistently, it reacts with simple inorganic and organic molecules to form GeF(3)(+)-L complexes (L = H(2)O, NH(3), C(2)H(2), C(2)H(4), C(6)H(6), CO(2), SO(2) and GeF(4)). Carbon 0-1 Rho guanine nucleotide exchange factor 3 Homo sapiens 76-82 17096536-12 2006 Furthermore, this study established the feasibility of using lipase catalysis to prepare polyesters from alpha,omega-linear aliphatic diethyl ester/diol monomers with less than six carbons. Carbon 181-188 PAN0_003d1715 Moesziomyces antarcticus 61-67 21464327-4 2011 We present carbon isotope data from 452 fossil teeth that record differential rates of diet change from C(3) to mixed C(3)/C(4) or C(4) diets among East African herbivore families at seven different time periods during the Late Miocene to the Pliocene (9.9-3.2 Ma). Carbon 11-17 complement C4A (Rodgers blood group) Homo sapiens 123-127 17415477-3 2006 The RANKL mRNA/OPG mRNA ratio in carbon ion-irradiated MC3T3-E1 cells was lower, while in gamma-irradiated MC3T3-E1 cells this ratio was higher than in non-irradiated cells. Carbon 33-39 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 4-9 33909189-6 2022 The results reveal that the sorption capacity of the carbonaceous adsorbents at a ratio 1:20 (solid to liquid phases) is orders of magnitude higher (13 368 ng mL-1 of activated carbon and 3 578 ng mL-1 of biochar) compared to the soil (57.8 ng mL-1). Carbon 53-59 L1 cell adhesion molecule Mus musculus 159-163 17415477-6 2006 This result is consistent with the lower RANKL/OPG mRNA ratio for carbon ion-irradiated cells. Carbon 66-72 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 41-46 17415477-7 2006 These results suggest that carbon ion irradiation acts primarily on osteoblastic cells, leading to a decrease in the RANKL/OPG mRNA ratio. Carbon 27-33 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 117-122 17144314-3 2006 Heterogeneous natural organic matter (NOM) present in all natural waters impedes trace organic contaminant adsorption, and predictive modeling of granular activated carbon (GAC) adsorber performance is often compromised by inadequate accounting forthese competitive effects. Carbon 165-171 glutaminase Homo sapiens 173-176 21384444-0 2011 T-shaped ionic liquid crystals based on the imidazolium motif: exploring substitution of the C-2 imidazolium carbon atom. Carbon 109-115 complement C2 Homo sapiens 93-96 21467295-6 2011 By linking genome stability, the cell cycle, and carbon catabolism, ATM emerges as a central regulator of cellular metabolism with implications for cancer. Carbon 49-55 ATM serine/threonine kinase Homo sapiens 68-71 33909189-6 2022 The results reveal that the sorption capacity of the carbonaceous adsorbents at a ratio 1:20 (solid to liquid phases) is orders of magnitude higher (13 368 ng mL-1 of activated carbon and 3 578 ng mL-1 of biochar) compared to the soil (57.8 ng mL-1). Carbon 53-59 L1 cell adhesion molecule Mus musculus 197-201 16797024-7 2006 The carboxylic group at the C-2 carbon cannot interact with tetraalkylammonium cations as strongly as does the C-17 carboxylic group, leading to different effects in the absence of carboxylic group at the C-2 or C-17 carbon in the molecules. Carbon 32-38 complement C2 Homo sapiens 28-31 33909189-6 2022 The results reveal that the sorption capacity of the carbonaceous adsorbents at a ratio 1:20 (solid to liquid phases) is orders of magnitude higher (13 368 ng mL-1 of activated carbon and 3 578 ng mL-1 of biochar) compared to the soil (57.8 ng mL-1). Carbon 53-59 L1 cell adhesion molecule Mus musculus 197-201 16797024-7 2006 The carboxylic group at the C-2 carbon cannot interact with tetraalkylammonium cations as strongly as does the C-17 carboxylic group, leading to different effects in the absence of carboxylic group at the C-2 or C-17 carbon in the molecules. Carbon 217-223 complement C2 Homo sapiens 28-31 16797024-7 2006 The carboxylic group at the C-2 carbon cannot interact with tetraalkylammonium cations as strongly as does the C-17 carboxylic group, leading to different effects in the absence of carboxylic group at the C-2 or C-17 carbon in the molecules. Carbon 217-223 cytokine like 1 Homo sapiens 111-115 33885177-7 2021 Further, it has been observed that the patients with PCSK9 rs11591147 TT genotype have significantly lower TC, LDL-C and higher HDL-C levels than individuals with GG genotype. Carbon 114-116 proprotein convertase subtilisin/kexin type 9 Homo sapiens 53-58 21727561-0 2006 In situ electrostatic assembly of CdS nanoparticles onto aligned multiwalled carbon nanotubes in aqueous solution. Carbon 77-83 CDP-diacylglycerol synthase 1 Homo sapiens 34-37 21727561-1 2006 A simple method is described for the electrostatic assembly of CdS nanoparticles onto oxidized aligned multiwalled carbon nanotubes (MWCNTs) in aqueous solution. Carbon 115-121 CDP-diacylglycerol synthase 1 Homo sapiens 63-66 21391634-0 2011 Stable carbon isotope enrichment factors for cis-1,2-dichloroethene and vinyl chloride reductive dechlorination by Dehalococcoides. Carbon 7-13 cytokine inducible SH2 containing protein Homo sapiens 45-50 33968889-9 2021 Both X-rays and Carbon ions promoted the exposure of HMGB1, IL-10, and TGF-beta in a time-dependent manner. Carbon 16-22 transforming growth factor alpha Mus musculus 71-79 21273120-8 2011 Moreover, we observed that at the entrance of the death phase carbon-metabolizing enzymes [such as the TCA cycle enzymes Mqo2 (malate: quinone oxidoreductase) and FumC/CitG (fumarate hydratase)] albeit not the bulk proteins are carbonylated to a larger extent in the clpC mutant. Carbon 62-68 AT695_RS05530 Staphylococcus aureus 135-157 33968889-11 2021 Besides, compared with X-rays, carbon ions increased the exposure of HMGB1 while relatively reduced the exposure levels of immunosuppressive factors IL-10 and TGF-beta. Carbon 31-37 transforming growth factor alpha Mus musculus 159-167 16846730-1 2006 The rate limiting steps in the conversion of 18-carbon unsaturated fatty acids to 20- and 22-carbon products are catalyzed by two desaturase enzymes (Delta5-desaturase and Delta6-desaturase) found within a lipid desaturase gene cluster. Carbon 48-54 fatty acid desaturase 1 Rattus norvegicus 156-167 33545223-5 2021 Here, we focus on dihydrofolate reductase (DHFR), a key enzyme in one-carbon metabolism, and demonstrate this enzyme"s overexpression in several human brain tumors and its expression in human BTIC. Carbon 70-76 dihydrofolate reductase Homo sapiens 18-41 16846730-1 2006 The rate limiting steps in the conversion of 18-carbon unsaturated fatty acids to 20- and 22-carbon products are catalyzed by two desaturase enzymes (Delta5-desaturase and Delta6-desaturase) found within a lipid desaturase gene cluster. Carbon 48-54 fatty acid desaturase 2 Rattus norvegicus 178-189 16839144-1 2006 Among pseudopeptidic foldamers, aza-beta3-peptides have the unique property to possess nitrogen stereocenters instead of carbon stereocenters. Carbon 121-127 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 36-41 21247114-0 2011 Synthesis and physicochemical characterization of carbon backbone modified [Gd(TTDA)(H2O)]2- derivatives. Carbon 50-56 general transcription factor IIH subunit 5 Homo sapiens 79-83 21247114-2 2011 Two new carbon backbone modified TTDA (3,6,10-tri(carboxymethyl)-3,6,10-triazadodecanedioic acid) derivatives, CB-TTDA and Bz-CB-TTDA, were synthesized. Carbon 8-14 general transcription factor IIH subunit 5 Homo sapiens 33-37 21247114-2 2011 Two new carbon backbone modified TTDA (3,6,10-tri(carboxymethyl)-3,6,10-triazadodecanedioic acid) derivatives, CB-TTDA and Bz-CB-TTDA, were synthesized. Carbon 8-14 general transcription factor IIH subunit 5 Homo sapiens 114-118 21247114-2 2011 Two new carbon backbone modified TTDA (3,6,10-tri(carboxymethyl)-3,6,10-triazadodecanedioic acid) derivatives, CB-TTDA and Bz-CB-TTDA, were synthesized. Carbon 8-14 general transcription factor IIH subunit 5 Homo sapiens 114-118 33545223-5 2021 Here, we focus on dihydrofolate reductase (DHFR), a key enzyme in one-carbon metabolism, and demonstrate this enzyme"s overexpression in several human brain tumors and its expression in human BTIC. Carbon 70-76 dihydrofolate reductase Homo sapiens 43-47 16834388-1 2006 The 4-coordinate, low-spin cob(I)alamin (Co1+Cbl) species, which can be obtained by heterolytic cleavage of the Co-C bond in methylcobalamin or the two-electron reduction of vitamin B12, is one of the most powerful nucleophiles known to date. Carbon 41-42 Cbl proto-oncogene Homo sapiens 45-48 33897464-4 2021 Medium- and long-chain fatty acids (6-12 and 13-21 carbon, respectively) target both FFAR1/GPR40 and FFAR4/GPR120. Carbon 51-57 free fatty acid receptor 1 Homo sapiens 85-90 33897464-4 2021 Medium- and long-chain fatty acids (6-12 and 13-21 carbon, respectively) target both FFAR1/GPR40 and FFAR4/GPR120. Carbon 51-57 free fatty acid receptor 1 Homo sapiens 91-96 21238729-3 2011 The CNFs, which were prepared by electrospinning technique and subsequent thermal treatment, were used to modify carbon paste electrode (CNF-CPE) to construct the amperometric sensor device without any oxidation pretreatment. Carbon 113-119 carboxypeptidase E Homo sapiens 141-144 33599041-3 2021 Here, an ionotronic gas-sensing sticker (IGS) is demonstrated, implemented with free-standing polymer electrolyte (ionic thermoplastic polyurethane, i-TPU) as a sensing channel and inkjet-printed stretchable carbon nanotube electrodes, which enables the IGS to exhibit high sensitivity, selectivity, stability (against mechanical stress, humidity, and temperature), and scalable fabrication, simultaneously. Carbon 208-214 gastrin Homo sapiens 20-23 21320339-4 2011 Within these coastal ecosystems, microalgal assemblages (microphytobenthos: MPB) are vital for autochthonous carbon fixation. Carbon 109-115 AFA1 Homo sapiens 76-79 21320339-5 2011 The level of in situ production by MPB mediates the net carbon cycling of transitional ecosystems between net heterotrophic or autotrophic metabolism. Carbon 56-62 AFA1 Homo sapiens 35-38 16388835-0 2006 A noval method of predicting soil organic carbon content normalized adsorption coefficients (Koc) of polybrominated biphenyls (PBBs). Carbon 42-48 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 93-96 16774208-7 2006 MP2/AVTZ infrared spectra are also given for the C(1) and C(3) isomers as guiding data for future IR studies in the gas phase. Carbon 49-50 tryptase pseudogene 1 Homo sapiens 0-3 33421896-4 2021 Immobilisation of the CYP2C9-FLD, CYP2C9*2-FLD and CYP2C9*3-FLD on DDAB modified glassy carbon electrodes showed well defined redox couples on the oxygen-free cyclic voltammograms and mid-point potentials of all enzymes were calculated. Carbon 88-94 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 22-28 16774208-7 2006 MP2/AVTZ infrared spectra are also given for the C(1) and C(3) isomers as guiding data for future IR studies in the gas phase. Carbon 58-59 tryptase pseudogene 1 Homo sapiens 0-3 33421896-4 2021 Immobilisation of the CYP2C9-FLD, CYP2C9*2-FLD and CYP2C9*3-FLD on DDAB modified glassy carbon electrodes showed well defined redox couples on the oxygen-free cyclic voltammograms and mid-point potentials of all enzymes were calculated. Carbon 88-94 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 34-40 16756305-0 2006 Dendron-tethered and templated CdS quantum dots on single-walled carbon nanotubes. Carbon 65-71 CDP-diacylglycerol synthase 1 Homo sapiens 31-34 33421896-4 2021 Immobilisation of the CYP2C9-FLD, CYP2C9*2-FLD and CYP2C9*3-FLD on DDAB modified glassy carbon electrodes showed well defined redox couples on the oxygen-free cyclic voltammograms and mid-point potentials of all enzymes were calculated. Carbon 88-94 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 34-40 33448131-4 2021 This review summarizes the recent progress on the synthesis of carbon-supported SACs and their application toward electrocatalytic CO2 reduction to CO and other C1 and C2 products. Carbon 63-69 heterogeneous nuclear ribonucleoprotein C Homo sapiens 161-170 16756305-1 2006 CdS nanoparticles on the surface of single-walled carbon nanotubes (SWNTs) were templated and stabilized through the initial attachment of 1 --> 3 C-branched amide-based dendrons and were both photophysically and morphologically characterized. Carbon 50-56 CDP-diacylglycerol synthase 1 Homo sapiens 0-3 16737271-4 2006 The delta(13)C of the olefinic carbons of the yet unknown bicyclo[1.1.0]but-1,3-ene 1 and bicyclo[2.1.0]pent-1(4)-ene 2 were computed to be 69.4 and 212.4, respectively, at the GIAO-CCSD(T)/qzp/tzp//MP2/cc-pVTZ level. Carbon 31-38 tryptase pseudogene 1 Homo sapiens 199-202 16737271-5 2006 The delta(13)C of the olefinic carbons of the intriguing (larger and also yet unknown) tricyclo[3.3.1.0(3,7)]non-3(7)-ene 6 and cubene 7 were calculated to be 172.5 and 187.4, respectively, at the GIAO-CCSD(T)/tzp/dz//MP2/cc-pVTZ level. Carbon 31-38 tryptase pseudogene 1 Homo sapiens 218-221 21178087-1 2011 The enzymes serine hydroxymethyltransferase 1 (gene name SHMT1) and methylenetetrahydrofolate reductase (gene name MTHFR) regulate key reactions in folate-mediated one-carbon metabolism. Carbon 168-174 serine hydroxymethyltransferase 1 Homo sapiens 57-62 21155555-4 2011 The most stable isomers of Co(1-2)C(2)H(-) clusters are linear with the C(2)H interacting with only one Co atom, while those of Co(3-5)C(2)H(-) cluster anions are quasi-planar structures with the carbon-carbon bonds bending slightly toward the Co(3-5) clusters. Carbon 27-28 complement C4A (Rodgers blood group) Homo sapiens 128-134 21155555-4 2011 The most stable isomers of Co(1-2)C(2)H(-) clusters are linear with the C(2)H interacting with only one Co atom, while those of Co(3-5)C(2)H(-) cluster anions are quasi-planar structures with the carbon-carbon bonds bending slightly toward the Co(3-5) clusters. Carbon 27-28 complement C4A (Rodgers blood group) Homo sapiens 244-250 21155555-4 2011 The most stable isomers of Co(1-2)C(2)H(-) clusters are linear with the C(2)H interacting with only one Co atom, while those of Co(3-5)C(2)H(-) cluster anions are quasi-planar structures with the carbon-carbon bonds bending slightly toward the Co(3-5) clusters. Carbon 196-202 complement C2 Homo sapiens 27-33 33831704-8 2021 Chemical characterization and density functional theory (DFT) calculation reveal that the Cd2+ recognition sites of functional groups are C-S and C S. Cd2+ mass transport in IIM suggest that the imprint effects provide a binding force that would delay Cd2+ to permeate through IIM, so as to selectively separate Cd2+ with other ions. Carbon 0-1 CD2 molecule Homo sapiens 90-93 21112760-2 2011 The mercaptopropionic acid-capped CdS quantum dots were firstly immobilized on carbon nanotubes modified electrode and then functionalized with carbohydrate using mannan as a model on the surface. Carbon 79-85 CDP-diacylglycerol synthase 1 Homo sapiens 34-37 21241135-5 2011 Interestingly, additional H(2) molecules can be bound to the carbon atoms at the chain ends due to the charge transfer between Li 2s2p (Na 3s) and C 2p states. Carbon 61-67 complement C2 Homo sapiens 147-151 16508916-3 2006 Notably, most of the 13C resonances of the taxane ring have two clearly resolved spectral components except the resonance peaks of C-15, C-16 and C-17, which are located at the central part of the taxane ring. Carbon 23-24 cytokine like 1 Homo sapiens 146-150 33831704-8 2021 Chemical characterization and density functional theory (DFT) calculation reveal that the Cd2+ recognition sites of functional groups are C-S and C S. Cd2+ mass transport in IIM suggest that the imprint effects provide a binding force that would delay Cd2+ to permeate through IIM, so as to selectively separate Cd2+ with other ions. Carbon 0-1 CD2 molecule Homo sapiens 151-154 16689936-5 2006 Protein sequencing revealed an intron is spliced from the transcript, and both transcription from the YBR230c gene and steady-state level of the Om14 protein is dramatically less in cells grown on glucose than in cells grown on nonfermentable carbon sources. Carbon 243-249 Om14p Saccharomyces cerevisiae S288C 145-149 33831704-8 2021 Chemical characterization and density functional theory (DFT) calculation reveal that the Cd2+ recognition sites of functional groups are C-S and C S. Cd2+ mass transport in IIM suggest that the imprint effects provide a binding force that would delay Cd2+ to permeate through IIM, so as to selectively separate Cd2+ with other ions. Carbon 0-1 CD2 molecule Homo sapiens 151-154 33831704-8 2021 Chemical characterization and density functional theory (DFT) calculation reveal that the Cd2+ recognition sites of functional groups are C-S and C S. Cd2+ mass transport in IIM suggest that the imprint effects provide a binding force that would delay Cd2+ to permeate through IIM, so as to selectively separate Cd2+ with other ions. Carbon 0-1 CD2 molecule Homo sapiens 151-154 22324412-11 2011 Wheat straw was the best carbon source for laccase synthesis in G. lucidum (55.75 U L-1). Carbon 25-31 L1 cell adhesion molecule Mus musculus 84-87 33745025-0 2021 Threshold effects of capital investments on carbon emissions in G20 economies. Carbon 44-50 chromosome 3 open reading frame 18 Homo sapiens 64-67 20969971-5 2011 These findings point to potential engineering targets for improving yield and increasing oil contents by, respectively, reducing substrate cycling and increasing the commitment of plastidic carbon into fatty acid synthesis at the level of pyruvate kinase. Carbon 190-196 pyruvate kinase Zea mays 239-254 21980519-1 2011 BACKGROUND: In filamentous ascomycete fungi, the utilization of alternate carbon sources is influenced by the zinc finger transcription factor CreA/CRE-1, which encodes a carbon catabolite repressor protein homologous to Mig1 from Saccharomyces cerevisiae. Carbon 74-80 Spt10p Saccharomyces cerevisiae S288C 148-153 16182303-2 2006 Positively charged hemoglobin (Hb) or myoglobin (Mb) in buffers at pH 5.5 or 5.0 was first adsorbed on the surface of acid-pretreated, negatively charged multiwalled carbon nanotubes (MWNTs) mainly by electrostatic interaction, forming a core-shell structure. Carbon 166-172 myoglobin Homo sapiens 38-47 16525679-8 2006 These data suggest that heavy carbon-ion beam irradiation combined with docetaxel may be a potentially useful therapeutic strategy for locally advanced esophageal SCC. Carbon 30-36 serpin family B member 3 Homo sapiens 163-166 33745025-3 2021 In light of this stark reality, this paper examines the threshold effects of capital investments on carbon emissions in G20 economies over the period, 1992-2014, for which data are available. Carbon 100-106 chromosome 3 open reading frame 18 Homo sapiens 120-123 16533058-4 2006 Like ionizing radiation (IR) and other radiomimetics, breaks induced by C-1027 efficiently activate ATM by phosphorylation at Ser1981, yet unlike other radiomimetics and IR, DNA breaks induced by C-1027 result in normal phosphorylation of p53 and the cell cycle checkpoint kinases (Chk1 and Chk2) in the absence of ATM. Carbon 72-73 ATM serine/threonine kinase Homo sapiens 100-103 16533058-4 2006 Like ionizing radiation (IR) and other radiomimetics, breaks induced by C-1027 efficiently activate ATM by phosphorylation at Ser1981, yet unlike other radiomimetics and IR, DNA breaks induced by C-1027 result in normal phosphorylation of p53 and the cell cycle checkpoint kinases (Chk1 and Chk2) in the absence of ATM. Carbon 72-73 ATM serine/threonine kinase Homo sapiens 315-318 33745025-7 2021 The findings of the latter approach indicate the relationship between capital investments and carbon emissions to be non-linear for the G20 countries. Carbon 94-100 chromosome 3 open reading frame 18 Homo sapiens 136-139 21980519-1 2011 BACKGROUND: In filamentous ascomycete fungi, the utilization of alternate carbon sources is influenced by the zinc finger transcription factor CreA/CRE-1, which encodes a carbon catabolite repressor protein homologous to Mig1 from Saccharomyces cerevisiae. Carbon 171-177 Spt10p Saccharomyces cerevisiae S288C 148-153 33616385-2 2021 Each product contains a positively charged trimethylammonioethenyl ligand, CH CH(+NMe3), that is derived from a 2-trimethylammonioethenide, -CH CH(+NMe3), zwitterion that formally has a positive charge on the nitrogen atom and a negative charge on the terminal enyl carbon atom. Carbon 266-272 NME/NM23 nucleoside diphosphate kinase 3 Homo sapiens 82-86 20730144-6 2010 We apply this new method in studies of the interaction of the carbon-rich interstellar species C(4)(X(3)Sigma) with atomic He. Carbon 62-68 complement C4A (Rodgers blood group) Homo sapiens 95-99 16506790-8 2006 In the case of the sulfonamidyl radicals, rearrangement via 1,2-shifts and beta-scission of the resultant C-2 carbon-centered radicals to yield SO(3)(*-) and C-2 imines is near quantitative based on the yield of SO(4)(2-), the decomposition product of SO(3)(*-). Carbon 110-116 complement C2 Homo sapiens 106-109 16506790-8 2006 In the case of the sulfonamidyl radicals, rearrangement via 1,2-shifts and beta-scission of the resultant C-2 carbon-centered radicals to yield SO(3)(*-) and C-2 imines is near quantitative based on the yield of SO(4)(2-), the decomposition product of SO(3)(*-). Carbon 110-116 complement C2 Homo sapiens 158-161 33721849-2 2021 It was expected that the resulting glassy carbon electrodes modified by 1D CNTs@NPC (CNTs@NPC/GCE) could express different electrochemical responses to ascorbic acid (AA), dopamine (DA), uric acid (UA), by virtue of the synergistic-improved effect between CNTs and NPC. Carbon 42-48 aminomethyltransferase Homo sapiens 85-97 16369050-6 2006 In contrast, if lysoPM and (14)C-labeled 20:4 were added to PC-3 or DU145 cells, (14)C-labeled PM was also formed, but the rate was neither higher in cells that overexpressed LPAAT-beta nor inhibited by CT-32501. Carbon 31-32 1-acylglycerol-3-phosphate O-acyltransferase 2 Homo sapiens 175-185 21105679-3 2010 In contrast, the reaction barriers for the O(2) additions of the carbon-centered radicals are ordered as ROO-CAR( ) > CAR(-H)( ) > LA( ). Carbon 65-71 CXADR pseudogene 1 Homo sapiens 109-112 21105679-3 2010 In contrast, the reaction barriers for the O(2) additions of the carbon-centered radicals are ordered as ROO-CAR( ) > CAR(-H)( ) > LA( ). Carbon 65-71 CXADR pseudogene 1 Homo sapiens 121-124 16711606-2 2006 2-O-Acyl moieties with one or more protons at the carbon atom adjacent to carbonyl group were found to migrate from C-2 to C-1 of the glycerol moiety during hydrogenation under Pd/C at room temperature. Carbon 50-56 complement C2 Homo sapiens 116-119 33721901-4 2021 Expression of DIN6 and DIN10, the carbon (C) starvation-responsive genes, was upregulated when nitrate was oversupplied under Pi starvation, which suggested that the plants recognized the oversupply of nitrate as C starvation stress because of the reduction in the C/N ratio. Carbon 34-40 Raffinose synthase family protein Arabidopsis thaliana 23-28 16711606-2 2006 2-O-Acyl moieties with one or more protons at the carbon atom adjacent to carbonyl group were found to migrate from C-2 to C-1 of the glycerol moiety during hydrogenation under Pd/C at room temperature. Carbon 50-56 heterogeneous nuclear ribonucleoprotein C Homo sapiens 123-126 32041489-7 2021 From MD trajectory analysis, we noticed that when OleA is bound to alpha-synuclein, the intramolecular distance between non-amyloid-beta component (NAC) domain and C-terminal domain of alpha-synuclein was increased, while long-range hydrophobic interactions between the two region was reduced. Carbon 150-151 synuclein alpha Homo sapiens 67-82 16291748-12 2006 The delta ndt1 delta ndt2 double mutant exhibited lower mitochondrial NAD+ and NADH levels than the single deletants and a more pronounced delay in growth on nonfermentable carbon sources. Carbon 173-179 NAD+ transporter Saccharomyces cerevisiae S288C 10-14 21033732-0 2010 Coating colloidal carbon spheres with CdS nanoparticles: microwave-assisted synthesis and enhanced photocatalytic activity. Carbon 18-24 CDP-diacylglycerol synthase 1 Homo sapiens 38-41 21033732-1 2010 This manuscript describes the accurate coating of CdS nanoparticles on the surface of colloidal carbon spheres by a facile two-step, microwave-assisted method and the studies on the photocatalytic activity of the C@CdS core-shell spheres. Carbon 96-102 CDP-diacylglycerol synthase 1 Homo sapiens 50-53 21033732-1 2010 This manuscript describes the accurate coating of CdS nanoparticles on the surface of colloidal carbon spheres by a facile two-step, microwave-assisted method and the studies on the photocatalytic activity of the C@CdS core-shell spheres. Carbon 96-102 CDP-diacylglycerol synthase 1 Homo sapiens 215-218 21033732-2 2010 For the coating of CdS nanoparticles, cadmium ions were incorporated into the hydrophilic shell of colloidal carbon spheres and reacted with an introduced sulfur source under a microwave field to obtain the C@CdS hybrid spheres. Carbon 109-115 CDP-diacylglycerol synthase 1 Homo sapiens 19-22 21033732-2 2010 For the coating of CdS nanoparticles, cadmium ions were incorporated into the hydrophilic shell of colloidal carbon spheres and reacted with an introduced sulfur source under a microwave field to obtain the C@CdS hybrid spheres. Carbon 19-20 CDP-diacylglycerol synthase 1 Homo sapiens 209-212 21033732-4 2010 A photoluminescence spectrum showed that the C@CdS hybrid spheres feature a broad green emission at around 494 nm (lambda(ex) = 337 nm). Carbon 45-46 CDP-diacylglycerol synthase 1 Homo sapiens 47-50 20444205-3 2010 The ear of gln1-3 and gln1-3/gln1-4 had a higher free amino acid content and a lower C/N ratio, when compared to the wild type. Carbon 85-86 glutamine synthetase, chloroplastic Zea mays 29-35 16405343-3 2006 In the first step, a proton from the hydroxyl oxygen on the second carbon of 2HM, or from the third carbon of 2o4hex, is abstracted by Pro-1. Carbon 67-73 lamin A/C Homo sapiens 135-140 16405343-3 2006 In the first step, a proton from the hydroxyl oxygen on the second carbon of 2HM, or from the third carbon of 2o4hex, is abstracted by Pro-1. Carbon 100-106 lamin A/C Homo sapiens 135-140 32041489-7 2021 From MD trajectory analysis, we noticed that when OleA is bound to alpha-synuclein, the intramolecular distance between non-amyloid-beta component (NAC) domain and C-terminal domain of alpha-synuclein was increased, while long-range hydrophobic interactions between the two region was reduced. Carbon 150-151 synuclein alpha Homo sapiens 185-200 33603190-6 2021 Compared to TLR3 alone, binding affinity to poly (I:C) is further increased in TLR3-CLEC18A and TLR3-CLEC18A(S339R) complexes. Carbon 52-54 toll-like receptor 3 Mus musculus 12-16 17120527-3 2006 We hypothesized that recently fixed carbon plays a key role in CCl4 metabolism in planta yielding nonvolatile trichloroacetic acid (TCA) and that the extent of this metabolism can be altered by heightening plant defenses. Carbon 36-42 C-C motif chemokine ligand 4 Homo sapiens 63-67 33603190-6 2021 Compared to TLR3 alone, binding affinity to poly (I:C) is further increased in TLR3-CLEC18A and TLR3-CLEC18A(S339R) complexes. Carbon 52-54 toll-like receptor 3 Mus musculus 79-83 17120527-6 2006 Autoradiography of [(11)C]photosynthate showed increased leaf export and partitioning to the apex within 24 h of CCl4 exposure, suggesting that changes in plant metabolism and partitioning of recently fixed carbon occur rapidly. Carbon 207-213 C-C motif chemokine ligand 4 Homo sapiens 113-117 33603190-6 2021 Compared to TLR3 alone, binding affinity to poly (I:C) is further increased in TLR3-CLEC18A and TLR3-CLEC18A(S339R) complexes. Carbon 52-54 toll-like receptor 3 Mus musculus 79-83 17120527-7 2006 Additionally, leaf CCl4 emissions were highest in the morning, when carbon pools are low, suggesting a link between contaminant metabolism and leaf carbon utilization. Carbon 68-74 C-C motif chemokine ligand 4 Homo sapiens 19-23 33854899-0 2021 Ultrafine MoP Nanoparticle Splotched Nitrogen-Doped Carbon Nanosheets Enabling High-Performance 3D-Printed Potassium-Ion Hybrid Capacitors. Carbon 52-58 opioid receptor mu 1 Homo sapiens 10-13 17120527-7 2006 Additionally, leaf CCl4 emissions were highest in the morning, when carbon pools are low, suggesting a link between contaminant metabolism and leaf carbon utilization. Carbon 148-154 C-C motif chemokine ligand 4 Homo sapiens 19-23 17018414-5 2006 The BOD5/TOC (5-day biological oxygen demand/total organic carbons) ratios of the ozonated Reactive Red 120 and Acid Red 299 solutions would increase and have the maximum values. Carbon 59-66 RNA binding motif protein 25 Homo sapiens 100-107 20977256-1 2010 The endocytic pathway of a recombinant protein toxin, ricin A-chain (RTA), delivered by multiwalled carbon nanotubes (MWCNTs) was tracked in HeLa cells by tagging RTA with enhanced green fluorescent protein (EGFP). Carbon 100-106 MAS related GPR family member F Homo sapiens 69-72 20688429-1 2010 This study investigates the impact of the type of virgin granular activated carbon (GAC) media used to synthesize iron (hydr)oxide nanoparticle-impregnated granular activated carbon (Fe-GAC) on its properties and its ability to remove arsenate and organic trichloroethylene (TCE) from water. Carbon 76-82 glutaminase Homo sapiens 84-87 20688429-1 2010 This study investigates the impact of the type of virgin granular activated carbon (GAC) media used to synthesize iron (hydr)oxide nanoparticle-impregnated granular activated carbon (Fe-GAC) on its properties and its ability to remove arsenate and organic trichloroethylene (TCE) from water. Carbon 175-181 glutaminase Homo sapiens 84-87 33854899-2 2021 In this work, a series of MoP nanoparticle splotched nitrogen-doped carbon nanosheets (MoP@NC) is synthesized. Carbon 68-74 opioid receptor mu 1 Homo sapiens 26-29 16376964-3 2006 In case of eight different kinds of commercial AC in pure water, the amount adsorbed at equilibrium concentration of 1 microg/L was in the range of 25.6-73.5mg/g for E1 and 21.3-67.6 mg/g for E2. Carbon 47-49 small nucleolar RNA, H/ACA box 73A Homo sapiens 166-175 33854899-2 2021 In this work, a series of MoP nanoparticle splotched nitrogen-doped carbon nanosheets (MoP@NC) is synthesized. Carbon 68-74 opioid receptor mu 1 Homo sapiens 87-90 16366534-0 2005 Fast carbon-carbon bond formation by a promiscuous lipase. Carbon 5-11 PAN0_003d1715 Moesziomyces antarcticus 51-57 32779873-3 2021 Compared to drugs targeting one-carbon metabolic enzymes (mainly dihydrofolate reductase and thymidylate synthase) that have been used for clinical treatment of cancer, efficient SHMT2-specific inhibitors are lacking. Carbon 32-38 thymidylate synthetase Homo sapiens 93-113 16366534-0 2005 Fast carbon-carbon bond formation by a promiscuous lipase. Carbon 12-18 PAN0_003d1715 Moesziomyces antarcticus 51-57 16366534-1 2005 Lipase B from Candida antarctica was redesigned to catalyze the promiscuous reaction of carbon-carbon bond formation. Carbon 88-94 PAN0_003d1715 Moesziomyces antarcticus 0-6 16366534-1 2005 Lipase B from Candida antarctica was redesigned to catalyze the promiscuous reaction of carbon-carbon bond formation. Carbon 95-101 PAN0_003d1715 Moesziomyces antarcticus 0-6 20833803-1 2010 PilO is an oligosaccharyl transferase (OTase) that catalyzes the O-glycosylation of Pseudomonas aeruginosa 1244 pilin by adding a single O-antigen repeating unit to the beta carbon of the C-terminal residue (a serine). Carbon 174-180 PilO Pseudomonas aeruginosa 0-4 33376139-1 2021 FAD-dependent bacterial oleate hydratases (OhyA) catalyze the addition of water to isolated fatty acid carbon-carbon double bonds. Carbon 103-109 AT695_RS03350 Staphylococcus aureus 24-41 21070419-6 2010 We used carbon isotope discrimination to show that TE is increased in AtCesA7(irx3-5) when compared with the WT. Carbon 8-14 Cellulose synthase family protein Arabidopsis thaliana 70-77 21805859-1 2010 It has been shown that calix[4]arene C-99 inhibited myosin subfragment-1 ATPase of myometrium. Carbon 37-38 myosin heavy chain 14 Homo sapiens 52-58 16193111-1 2005 A neutral electrochemical chemosensor based on TTF exhibited high selectivity for H2PO4- over a wide range of anions and the significant C-H...O hydrogen bonding between C=C-H of the TTF unit and H2PO4- played an important role in regulating the selectivity. Carbon 137-138 ras homolog family member H Homo sapiens 47-50 16193111-1 2005 A neutral electrochemical chemosensor based on TTF exhibited high selectivity for H2PO4- over a wide range of anions and the significant C-H...O hydrogen bonding between C=C-H of the TTF unit and H2PO4- played an important role in regulating the selectivity. Carbon 137-138 ras homolog family member H Homo sapiens 183-186 16193111-1 2005 A neutral electrochemical chemosensor based on TTF exhibited high selectivity for H2PO4- over a wide range of anions and the significant C-H...O hydrogen bonding between C=C-H of the TTF unit and H2PO4- played an important role in regulating the selectivity. Carbon 170-171 ras homolog family member H Homo sapiens 47-50 16193111-1 2005 A neutral electrochemical chemosensor based on TTF exhibited high selectivity for H2PO4- over a wide range of anions and the significant C-H...O hydrogen bonding between C=C-H of the TTF unit and H2PO4- played an important role in regulating the selectivity. Carbon 170-171 ras homolog family member H Homo sapiens 183-186 16171347-2 2005 The thermal transformations of as-deposited Fe(CO)(5) films adsorbed on Au(111)/mica and C(4), C(8), C(12), and C(16) self-assembled methyl-terminated monolayer organic surfaces have been studied using infrared spectroscopy to probe how the physical restructuring influences the sensitivity of these systems to low-energy electron beams. Carbon 47-48 complement C4A (Rodgers blood group) Homo sapiens 89-93 20732719-7 2010 There was a significant difference among the different carbon nanotube-based nanomaterials in their level of stimulation of IL-1beta in macrophage cells and the dose at which they became stimulatory. Carbon 55-61 interleukin-1 beta Oncorhynchus mykiss 124-132 33376139-1 2021 FAD-dependent bacterial oleate hydratases (OhyA) catalyze the addition of water to isolated fatty acid carbon-carbon double bonds. Carbon 103-109 AT695_RS03350 Staphylococcus aureus 43-47 16173708-2 2005 PMI Sc(OTf)3 is highly active in several fundamental carbon-carbon bond-forming reactions. Carbon 53-59 POU class 5 homeobox 1 Homo sapiens 4-12 33376139-1 2021 FAD-dependent bacterial oleate hydratases (OhyA) catalyze the addition of water to isolated fatty acid carbon-carbon double bonds. Carbon 110-116 AT695_RS03350 Staphylococcus aureus 24-41 16173708-2 2005 PMI Sc(OTf)3 is highly active in several fundamental carbon-carbon bond-forming reactions. Carbon 60-66 POU class 5 homeobox 1 Homo sapiens 4-12 33376139-1 2021 FAD-dependent bacterial oleate hydratases (OhyA) catalyze the addition of water to isolated fatty acid carbon-carbon double bonds. Carbon 110-116 AT695_RS03350 Staphylococcus aureus 43-47 16853246-2 2005 The surface chemistry of carbon-nitrogen coupling is of fundamental importance to catalytic processes such as the industrial-scale synthesis of HCN from CH4 and NH3 over Pt. Carbon 25-31 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 144-147 33413430-4 2021 Interestingly, NK-4 augmented TNF-alpha production by THP-1 macrophages in combination with LPS, Pam3CSK4, or poly(I:C). Carbon 101-102 interleukin 32 Homo sapiens 15-19 20854852-7 2010 In this study, S. cerevisiae using glycerol as substrate was modified through one-step gene disruption for redirection of glycerol carbon flux into ethanol by the deletion of two glycerol production genes, FPS1 and GPD2. Carbon 131-137 glycerol-3-phosphate dehydrogenase (NAD(+)) GPD2 Saccharomyces cerevisiae S288C 215-219 16144384-1 2005 We report complementary detection of prostate-specific antigen (PSA) using n-type In2O3 nanowires and p-type carbon nanotubes. Carbon 109-115 kallikrein related peptidase 3 Homo sapiens 37-68 33407038-10 2022 The influence of the MET system on the organic matter removal was evident in two reactors, where this technology was applied, with respect to the control ones: total organic carbon decreased on average 13%, while it reduced less than 5% in the control reactors. Carbon 174-180 SAFB like transcription modulator Homo sapiens 21-24 16046082-1 2005 The Escherichia coli strain Pgi-UdhA, a mutant of the strain MG1655, is deficient in both the pgi gene and the udhA gene and cannot grow on glucose as carbon and energy source. Carbon 151-157 glucose-6-phosphate isomerase Escherichia coli str. K-12 substr. MG1655 28-31 20845939-5 2010 Thus, optimal thermal properties were obtained with monomers having RR absolute configuration of the C-2 and C-5 carbon atoms (isomannide configuration). Carbon 113-119 complement C5 Homo sapiens 109-112 15812659-2 2005 We found that papaya embryogenic calli have little or no PMI activity and cannot utilize Man as a carbon source; however, when calli were transformed with a pmi gene, the PMI activity was greatly increased and they could utilize Man as efficiently as sucrose. Carbon 98-104 mannose phosphate isomerase Homo sapiens 157-160 32763698-6 2021 The density functional theory study of the carbon quantum dots/TiO2 interface revealed that C 2p states of carbon quantum dots incorporated new energy states around the Fermi level near the lowest conduction band. Carbon 43-49 complement C2 Homo sapiens 92-96 15813700-6 2005 Gup1p belongs to the list of yeast proteins rapidly down-regulated by changing the carbon source in the culture medium, in agreement with the concept that post-translational modifications triggered by glucose affect proteins of peripheral functions. Carbon 83-89 O-acyltransferase Saccharomyces cerevisiae S288C 0-5 20607191-0 2010 Growth of CdS nanoparticles on the aligned carbon nanotubes. Carbon 43-49 CDP-diacylglycerol synthase 1 Homo sapiens 10-13 20607191-1 2010 A simple method for formation of CdS nanoparticles on the surface of carbon nanotubes (CNTs) aligned perpendicularly to the silicon substrate has been developed. Carbon 69-75 CDP-diacylglycerol synthase 1 Homo sapiens 33-36 20653776-2 2010 Deletion of MRS2, LPE10 or both results in a petite phenotype, which exhibits a respiratory growth defect on nonfermentable carbon sources. Carbon 124-130 Mfm1p Saccharomyces cerevisiae S288C 18-23 32763698-6 2021 The density functional theory study of the carbon quantum dots/TiO2 interface revealed that C 2p states of carbon quantum dots incorporated new energy states around the Fermi level near the lowest conduction band. Carbon 107-113 complement C2 Homo sapiens 92-96 20698690-1 2010 Structural, spectroscopic, and electronic features of weak hydrogen-bonded complexes of CpM(CO)(3)H (M = Mo (1a), W (1b)) hydrides with organic bases (phosphine oxides R(3)PO (R = n-C(8)H(17), NMe(2)), amines NMe(3), NEt(3), and pyridine) are determined experimentally (variable temperature IR) and computationally (DFT/M05). Carbon 88-89 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 193-199 20698690-1 2010 Structural, spectroscopic, and electronic features of weak hydrogen-bonded complexes of CpM(CO)(3)H (M = Mo (1a), W (1b)) hydrides with organic bases (phosphine oxides R(3)PO (R = n-C(8)H(17), NMe(2)), amines NMe(3), NEt(3), and pyridine) are determined experimentally (variable temperature IR) and computationally (DFT/M05). Carbon 88-89 NME/NM23 nucleoside diphosphate kinase 3 Homo sapiens 209-215 16124297-3 2005 In the present study, the abiotic dehalogenation of CCl4 by Fe(II) present at the surface of different iron minerals has been characterized in terms of the reaction rates and carbon isotopic fractionation (delta13C) of carbon tetrachloride (CCl4) as well as the yields and isotopic signatures of chloroform (CHCl3), one of the main transformation products. Carbon 175-181 C-C motif chemokine ligand 4 Homo sapiens 52-56 16124297-4 2005 The abiotic reductive dehalogenation of CCl4 was associated with substantial carbon isotopic enrichment effects. Carbon 77-83 C-C motif chemokine ligand 4 Homo sapiens 40-44 31622199-8 2021 In addition, DHFR inhibitors acting on thymidylate synthase (TS), carbon anhydrase (CA) and even DNA-binding are presented in this paper. Carbon 66-72 dihydrofolate reductase Homo sapiens 13-17 16124297-8 2005 Conversely, CCl4 transformation by different preparations of the iron sulfide mackinawite was accompanied by a significantly lower carbon istotopic fractionation (e = -15.9 +/- 0.3 per thousand), possibly due to the presence of nonfractionating rate-determining steps or a significantly different transition state structure of the reaction. Carbon 131-137 C-C motif chemokine ligand 4 Homo sapiens 12-16 20463021-3 2010 Two multifunctional peroxisomal isozymes, MFP2 and AIM1, both with 2-trans-enoyl-CoA hydratase and l-3-hydroxyacyl-CoA dehydrogenase activities, function in mouse ear cress (Arabidopsis thaliana) peroxisomal beta-oxidation, where fatty acids are degraded by the sequential removal of two carbon units. Carbon 288-294 Enoyl-CoA hydratase/isomerase family Arabidopsis thaliana 51-55 33383149-8 2021 The rIL-33 pre-treated mice in both Poly I:C and ConA challenge groups showed significantly (P <= 0.05) lower levels of AST and ALT, and decreased liver injury (parenchymal and per-vascular necrotic areas) in histological liver sections. Carbon 43-44 solute carrier family 17 (anion/sugar transporter), member 5 Mus musculus 120-123 21179939-4 2010 We examine here the effects of multiwalled carbon nanotubes of different sizes on monocytic THP-1 cells, with regard to their ability to stimulate increased expression of the HO-1 and GST genes and their ability to produce nuclear translocation of the transcription factor, Nrf2, as well as the release of several pro-inflammatory cytokines and mediators of inflammation. Carbon 43-49 heme oxygenase 1 Homo sapiens 175-179 21179939-5 2010 Our results suggest that long (50 microm) carbon nanotubes (62.5 microg/ml for 4 hours) produce increased nuclear translocation of Nrf2 and increased HO-1 gene expression compared with shorter entangled nanotubes. Carbon 42-48 heme oxygenase 1 Homo sapiens 150-154 15872116-5 2005 S20 has three chiral carbons and was resolved into its two enantiomers. Carbon 21-28 ribosomal protein S20 Homo sapiens 0-3 16006999-2 2005 We hypothesized that polymorphisms of the cytosolic serine hydroxymethyltransferase (SHMT1) gene involved in folate-dependent, one-carbon metabolism are associated with SCCHN risk. Carbon 131-137 serine hydroxymethyltransferase 1 Homo sapiens 42-83 16006999-2 2005 We hypothesized that polymorphisms of the cytosolic serine hydroxymethyltransferase (SHMT1) gene involved in folate-dependent, one-carbon metabolism are associated with SCCHN risk. Carbon 131-137 serine hydroxymethyltransferase 1 Homo sapiens 85-90 33383149-8 2021 The rIL-33 pre-treated mice in both Poly I:C and ConA challenge groups showed significantly (P <= 0.05) lower levels of AST and ALT, and decreased liver injury (parenchymal and per-vascular necrotic areas) in histological liver sections. Carbon 43-44 glutamic pyruvic transaminase, soluble Mus musculus 128-131 33383916-0 2020 Comparative Study of Phosgene Gas Sensing Using Carbon and Boron Nitride Nanomaterials-A DFT Approach. Carbon 48-54 gastrin Homo sapiens 30-33 15893773-8 2005 In short-term incubations of MIN6 cells with either adiponectin (2.5 microg/ml) or AICAR (1 mM), the flux of glucose-carbon to acyl CoA/cholesterol biosynthetic intermediates was reduced. Carbon 117-123 adiponectin, C1Q and collagen domain containing Mus musculus 52-63 16028958-3 2005 The C-S bond cleavage to form metallacyclic Re(V) complexes with a ReS core occurs only for the complexes with mtp and pdt frameworks and X = SAr and SC(2)H(5). Carbon 4-5 metallothionein 1B Homo sapiens 111-114 19898963-6 2010 Secretion of beta-glucosidase was found to be clearly dependent on the composition of the carbon source, and in the case of lactose, 2-fold higher specific activity was observed compared to Solka Floc and steam-pre-treated corn stover. Carbon 90-96 beta-glucosidase Zea mays 13-29 33374659-3 2020 In this work, zinc oxide and carbon co-modified LiFePO4 nanomaterials (LFP/C-ZnO) were prepared by an inorganic-based hydrothermal route, which vastly boosts its performance. Carbon 29-35 lamin A/C Homo sapiens 71-74 20406909-3 2010 To demonstrate its capabilities, we have tracked structural changes in myoglobin as it undergoes a photolysis-induced transition from its carbon monoxy form (MbCO) to its deoxy form (Mb). Carbon 138-144 myoglobin Homo sapiens 71-80 15911613-0 2005 Methionine sulfoximine treatment and carbon starvation elicit Snf1-independent phosphorylation of the transcription activator Gln3 in Saccharomyces cerevisiae. Carbon 37-43 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 126-130 15911613-7 2005 Gln3-Myc13 phosphorylation levels are regulated by at least three mechanisms as follows: (i) depends on Snf1 kinase as observed during carbon starvation, (ii) is Snf1-independent as observed during both carbon starvation and MSX treatment, and (iii) is rapamycin-induced dephosphorylation. Carbon 135-141 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 0-4 15911613-7 2005 Gln3-Myc13 phosphorylation levels are regulated by at least three mechanisms as follows: (i) depends on Snf1 kinase as observed during carbon starvation, (ii) is Snf1-independent as observed during both carbon starvation and MSX treatment, and (iii) is rapamycin-induced dephosphorylation. Carbon 203-209 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 0-4 33249982-5 2021 Histological analysis of StVPE1-GFP in BY-2 cells showed that carbon starvation induces its translocation from the endoplasmic reticulum to the central vacuole through tonoplast engulfment. Carbon 62-68 vacoular processing enzyme 2 Solanum tuberosum 25-31 15892146-10 2005 For sake of comparison, the reactions of [AlH3(NMe3)] and [GaH3(quin)] with the bulky carbodiimide ArN=C=NAr and the thiourea Ar(H)NC(=S)N(H)Ar were examined. Carbon 103-104 NME/NM23 nucleoside diphosphate kinase 3 Homo sapiens 47-51 20672135-1 2010 Cu2S nanocrystal particles were in situ deposited on graphite paper to prepare nano-sulfide/carbon composite counter electrode for CdS/CdSe quantum-dot-sensitized solar cell (QDSC). Carbon 92-98 CDP-diacylglycerol synthase 1 Homo sapiens 131-134 20226934-13 2010 When the size of the molecule was even larger, such as bovine insulin (C(254)H(377)N(65)O(75)S(6)), Kragten procedure provided a good estimate for the uncertainty when the most probable isotope composition of carbon in mammals was used in the calculations. Carbon 209-215 insulin Bos taurus 62-69 33419356-1 2020 This paper presents the results of laser welding of dissimilar joints, where low-carbon and stainless steels were welded inthe lap joint configuration. Carbon 81-87 LAP Homo sapiens 127-130 20137858-2 2010 With positron emission tomography, using a [11]-Carbon labeled NK1 receptor antagonist, we demonstrate attenuated NK1 receptor availability in frontal, insular and cingulate cortex, as well as the hippocampus, amygdala and the periaqueductal gray area in patients with chronic pain. Carbon 48-54 tachykinin receptor 1 Homo sapiens 63-75 20137858-2 2010 With positron emission tomography, using a [11]-Carbon labeled NK1 receptor antagonist, we demonstrate attenuated NK1 receptor availability in frontal, insular and cingulate cortex, as well as the hippocampus, amygdala and the periaqueductal gray area in patients with chronic pain. Carbon 48-54 tachykinin receptor 1 Homo sapiens 114-126 15969521-5 2005 The organic carbon adsorption constant (Koc) of thiamethoxam was 0.53 in Lihue soil and 0.23 in Wahiawa soil. Carbon 12-18 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 40-43 15969584-0 2005 Effect of tip functionalization on transport through vertically oriented carbon nanotube membranes. Carbon 73-79 TOR signaling pathway regulator Homo sapiens 10-13 16852362-1 2005 Carbon/molecule/copper molecular electronic junctions were fabricated by metal deposition of copper onto films of various thicknesses of fluorene (FL), biphenyl (BP), and nitrobiphenyl (NBP) covalently bonded to flat, graphitic carbon. Carbon 0-6 NUBP iron-sulfur cluster assembly factor 1, cytosolic Homo sapiens 186-189 33186034-4 2020 Then, to direct more carbon flux toward the pentose phosphate pathway, we reduced the expression of phosphoglucose isomerase by replacing its native promoter with a weaker promoter, and increased the expression of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase by replacing their native promoters with stronger promoters. Carbon 21-27 glucose-6-phosphate dehydrogenase Saccharomyces cerevisiae S288C 214-247 15788482-10 2005 After the ezrin oligomers were separated from monomers, FRET was observed in both forms, indicating intramolecular and intermolecular N-C binding. Carbon 136-137 ezrin Homo sapiens 10-15 20089293-8 2010 The inhibition of BChE by micro-scaled activated carbon and Cu particles was significantly lower than that of their nano-scaled particles. Carbon 49-55 butyrylcholinesterase Homo sapiens 18-22 19853376-1 2010 The present study investigated the adsorptive ability of carbon materials (C1 and C2) released during the combustion of woody biomass. Carbon 57-63 heterogeneous nuclear ribonucleoprotein C Homo sapiens 75-84 19853376-4 2010 The saturated adsorption amounts of nitrobenzene were 294 mg/g for C1 and 344 mg/g for the activated carbon powder. Carbon 101-107 heterogeneous nuclear ribonucleoprotein C Homo sapiens 67-77 15921974-1 2005 Two series of novel tetrahydroisoquinoline derivatives bearing at C-1 position a carbon chain derived from fatty acids were prepared employing two complementary synthetic methodologies. Carbon 81-87 heterogeneous nuclear ribonucleoprotein C Homo sapiens 66-69 33339358-1 2020 The emergence and development of car-sharing has not only satisfied people"s diverse travel needs, but also brought new solutions for improving urban traffic conditions and achieving low-carbon and green sustainable development. Carbon 187-193 CXADR pseudogene 1 Homo sapiens 33-36 15852111-5 2005 In the presence of PPh3, complexes act as a Michael acceptor to afford the zwitterionic sigma-allenylphosphonium complexes (eta5-MeC5H4)(CO)2MnC(R)=C=C(PPh3)R" (5) resulting from nucleophilic attack by the phosphine on the remote alkynyl carbon atom. Carbon 131-132 protein phosphatase 4 catalytic subunit Homo sapiens 19-23 15852111-5 2005 In the presence of PPh3, complexes act as a Michael acceptor to afford the zwitterionic sigma-allenylphosphonium complexes (eta5-MeC5H4)(CO)2MnC(R)=C=C(PPh3)R" (5) resulting from nucleophilic attack by the phosphine on the remote alkynyl carbon atom. Carbon 131-132 protein phosphatase 4 catalytic subunit Homo sapiens 152-156 15852111-5 2005 In the presence of PPh3, complexes act as a Michael acceptor to afford the zwitterionic sigma-allenylphosphonium complexes (eta5-MeC5H4)(CO)2MnC(R)=C=C(PPh3)R" (5) resulting from nucleophilic attack by the phosphine on the remote alkynyl carbon atom. Carbon 137-138 protein phosphatase 4 catalytic subunit Homo sapiens 19-23 19914676-2 2010 While previous studies showed that the side chain acetyl group of L-AcK can be extended to bulkier acyl groups for Sir2 (including SIRT1)-catalyzed lysine N(epsilon)-deacylation reaction, our current study suggested that SIRT1-catalyzed deacetylation reaction had a very stringent requirement for the distance between the alpha-carbon and the side chain acetamido group, with that found in L-AcK being optimal. Carbon 328-334 tyrosine kinase non receptor 2 Homo sapiens 68-71 19914676-2 2010 While previous studies showed that the side chain acetyl group of L-AcK can be extended to bulkier acyl groups for Sir2 (including SIRT1)-catalyzed lysine N(epsilon)-deacylation reaction, our current study suggested that SIRT1-catalyzed deacetylation reaction had a very stringent requirement for the distance between the alpha-carbon and the side chain acetamido group, with that found in L-AcK being optimal. Carbon 328-334 sirtuin 2 Homo sapiens 115-119 33425736-8 2020 Notably, our study allows us to suggest that miR-3143 regulates the carbon metabolism by targeting hexokinase-2. Carbon 68-74 microRNA 3143 Homo sapiens 45-53 19950333-1 2010 Using density functional calculations, we demonstrate that the planarity of the nonclassical planar tetracoordinate carbon (ptC) arrangement can be utilized to construct new families of flat, tubular, and cage molecules which are geometrically akin to graphenes, carbon nanotubes, and fullerenes but have fundamentally different chemical bonds. Carbon 116-122 coiled-coil domain containing 6 Homo sapiens 124-127 15839661-4 2005 Enynamides serve as 4pi components in a complementary version of the cycloaddition strategy which provides access to indoles and indolines substituted with carbon substituents at C-4. Carbon 156-162 complement C4A (Rodgers blood group) Homo sapiens 179-182 15839688-0 2005 Synthesis and characterization of stable hypervalent carbon compounds (10-C-5) bearing a 2,6-bis(p-substituted phenyloxymethyl)benzene ligand. Carbon 53-59 complement C5 Homo sapiens 74-77 19950333-1 2010 Using density functional calculations, we demonstrate that the planarity of the nonclassical planar tetracoordinate carbon (ptC) arrangement can be utilized to construct new families of flat, tubular, and cage molecules which are geometrically akin to graphenes, carbon nanotubes, and fullerenes but have fundamentally different chemical bonds. Carbon 263-269 coiled-coil domain containing 6 Homo sapiens 124-127 19950333-3 2010 Starbenzene is an aromatic molecule with six pi electrons, but its carbon atoms prefer ptC arrangements rather than the planar trigonal sp(2) arrangements like those in benzene. Carbon 67-73 coiled-coil domain containing 6 Homo sapiens 87-90 33415004-8 2020 When used in combination with miR-29b mimic, carbon ion beam markedly inhibited invasion, migration, and proliferation of OSA cells and promoted apoptosis by inhibiting AKT phosphorylation in a Sp1/PTEN-mediated manner. Carbon 45-51 phosphatase and tensin homolog Homo sapiens 198-202 33415004-9 2020 Taken together, miR-29b mimic improved the radiosensitivity of OSA cells via the PTEN-AKT-Sp1 signaling pathway, presenting a novel strategy for the development of carbon ion beam combination therapy. Carbon 164-170 phosphatase and tensin homolog Homo sapiens 81-85 15826157-0 2005 Chelate and pincer carbene complexes of rhodium and platinum derived from hexaphenylcarbodiphosphorane, Ph3P=C=PPh3. Carbon 0-1 protein phosphatase 4 catalytic subunit Homo sapiens 111-115 33339804-1 2020 Cotton cloth waste was used as a precursor to prepare activated carbon (ACCs) chemically activated with phosphoric acid. Carbon 64-70 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Homo sapiens 72-76 15826157-1 2005 The reaction of [(cod)RhCl]2 with Ph3P=C=PPh3 (1) gave the bidentate Rh(I) carbene complex, (cod)Rh[eta2-C{P(C6H4)Ph2}{PPh3}] (2), in which one of the Ph groups in 1 underwent orthometalation to form the chelate. Carbon 24-25 protein phosphatase 4 catalytic subunit Homo sapiens 41-45 15826157-1 2005 The reaction of [(cod)RhCl]2 with Ph3P=C=PPh3 (1) gave the bidentate Rh(I) carbene complex, (cod)Rh[eta2-C{P(C6H4)Ph2}{PPh3}] (2), in which one of the Ph groups in 1 underwent orthometalation to form the chelate. Carbon 24-25 protein phosphatase 4 catalytic subunit Homo sapiens 119-123 23113038-11 2010 In this comparative study, MARS obtained different findings from C&RT in dependency level prediction. Carbon 65-66 methionyl-tRNA synthetase 1 Homo sapiens 27-31 20157245-9 2010 Therefore, one-carbon metabolism alteration seems to be a cause of deregulation of the equilibrium between GSK3beta and PP2A, leading to abnormal hyperphosphorylated tau. Carbon 15-21 protein phosphatase 2 phosphatase activator Homo sapiens 120-124 20157245-9 2010 Therefore, one-carbon metabolism alteration seems to be a cause of deregulation of the equilibrium between GSK3beta and PP2A, leading to abnormal hyperphosphorylated tau. Carbon 15-21 microtubule associated protein tau Homo sapiens 166-169 33243973-4 2020 Inhibition of serine or glycine uptake from the extracellular milieu, as well as knockdown of the cytosolic one-carbon metabolism enzyme serine hydroxymethyltransferase (SHMT1), abolishes migration. Carbon 112-118 serine hydroxymethyltransferase 1 Homo sapiens 170-175 19839618-2 2009 The first mechanism consists of the direct dissociation (homolysis) of the carbon nitrogen bond (CH(3)C(6)H(4)NO(2) = CH(3)C(6)H(4) + NO(2)) whereas the second one is a more complex process initiated by C-H alpha attack and leading to the formation of anthranil and water (C(6)H(4)C(H)ON + H(2)O). Carbon 75-81 transcription factor like 5 Homo sapiens 203-212 15741088-3 2005 Cholesterol esterase, cholesterol oxidase, peroxidase and potassium ferrocyanide were immobilized on the screen-printed carbon electrodes. Carbon 120-126 carboxyl ester lipase Homo sapiens 0-20 15766878-3 2005 The chimeric carrier, Anc2-Cyc1(His6)p, was able to restore growth on a non-fermentable carbon source of a yeast strain devoid of functional ADP/ATP carrier, which demonstrated its transport activity. Carbon 88-94 cytochrome c isoform 1 Saccharomyces cerevisiae S288C 27-31 33175529-4 2020 The C, E-N-CNT/carbon black (C, E-N-CNT/C) demonstrates exciting oxygen reduction reaction (ORR) electrocatalysis with exceptionally low-onset potential (E0, 913 mV versus RHE) and satisfactory half-wave potential (E1/2, merely -7.3 mV shift compared with that of commercial 20% platinum/C (Pt/C)). Carbon 15-21 ret proto-oncogene Homo sapiens 291-295 15771433-3 2005 Attempts to optimize a cyclin-dependent kinase-1 (CDK1) inhibitor by using palladium-catalyzed C-C bond, C-N bond formation reactions to assemble diverse biheteroaryl molecules led to the unexpected discovery of a pyrazine-pyridine biheteroaryl as a novel series of potent VEGFR-2 inhibitors. Carbon 50-51 cyclin dependent kinase 1 Homo sapiens 23-48 33329669-4 2020 Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability. Carbon 271-277 cycling DOF factor 3 Arabidopsis thaliana 52-56 15609373-4 2005 A quaternary carbon signal at delta 172.88 ppm was assigned to C-2 carbonyl of the compound. Carbon 13-19 complement C2 Homo sapiens 63-66 19910432-3 2009 The aim of this study was to synthesize and evaluate (11)C-labeled GSK189254 ((11)C-GSK189254) for imaging the histamine H(3) receptor in vivo by PET. Carbon 57-58 histamine receptor H3 Homo sapiens 111-134 26631799-1 2009 We investigated the binding nature of three peptides (inactive NB1 and active B1 and B3) to single-walled carbon nanotubes (SWCNTs) using a density functional tight-binding (DFTB) method with an empirical van der Waals force correction. Carbon 106-112 CD177 molecule Homo sapiens 63-87 15593245-2 2005 Comparing the assignments with those of rapamycin showed that in the published 13C assignments of rapamycin in DMSO-d6 the shifts for C-12 and C-42 have been interchanged, as well as the shifts for C-1 and C-8. Carbon 0-1 heterogeneous nuclear ribonucleoprotein C Homo sapiens 198-209 33143571-3 2022 To illustrate the applicability of the ACEI, the adsorption of CO2 and N2 was investigated on two kinds of activated carbons (ACs), which were used for gas purification and bulk separation. Carbon 117-124 gastrin Homo sapiens 152-155 15619712-2 2005 Previous studies have demonstrated that herbicides with a low soil organic carbon partition coefficient (K(oc)) are preferentially removed from concrete and asphalt surfaces. Carbon 75-81 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 105-110 19911560-1 2009 With mounting pressure on hospitals and other healthcare facilities to reduce their energy bills, coupled with the need to reduce their carbon footprint, developer and supplier of combined heat and power systems Cogenco argues that adding CHP plant to existing energy generation equipment such as gas boilers has never made greater financial sense. Carbon 136-142 calcineurin like EF-hand protein 1 Homo sapiens 239-242 19756312-1 2009 The recombined ricin A chain protein (RTA) was transported into living cells by multiwalled carbon nanotubes (MWNTs) as a cellular carrier, as performed by natural ricin B chain protein (RTB). Carbon 92-98 MAS related GPR family member F Homo sapiens 38-41 19756312-7 2009 This is the first example of recombined protein toxin (RTA)-induced targeting destruction for tumor cells via carbon nanotube molecular transporters. Carbon 110-116 MAS related GPR family member F Homo sapiens 55-58 33169998-0 2020 Intramolecular Hydrogen Bonds in Tip-Functionalized Single-Walled Carbon Nanotubes as pH-Sensitive Gates. Carbon 66-72 TOR signaling pathway regulator Homo sapiens 33-36 19761651-6 2009 In Experiment 2, the lower vitamin E+C treatment attenuated spatial memory deficits in APP/PSEN1 mice and improved performance in wild-type mice in the water maze. Carbon 37-38 presenilin 1 Mus musculus 91-96 15638492-2 2005 A "traceless" silicon linker was employed with the silicon-carbon bonding being cleaved with TFA. Carbon 59-65 coagulation factor III, tissue factor Homo sapiens 93-96 33251459-3 2020 It was found that the carbon content of CG was increased by 37.8% from 57.4% (corn flour) to 95.2% (CG). Carbon 22-28 cathepsin G Homo sapiens 40-42 15913015-3 2005 Based on kinetic and equilibrium study results, spent activated carbon with a grain size of 0.3-0.5 mm and washed with distilled water (designated as WAC) was selected for fixed column studies. Carbon 64-70 WW domain containing adaptor with coiled-coil Homo sapiens 150-153 15519155-1 2004 To improve the biological activities of chrysin (CR), we synthesize Diethyl Chysin-7-yl phosphate (CPE: C(19)H(19)O(7)P) and tetraethyl bis-phosphoric ester of chrysin (CP: C(23)H(28)O(10)P(2)) through a simplified Atheron-Todd reaction. Carbon 49-50 carboxypeptidase E Homo sapiens 99-102 15519155-1 2004 To improve the biological activities of chrysin (CR), we synthesize Diethyl Chysin-7-yl phosphate (CPE: C(19)H(19)O(7)P) and tetraethyl bis-phosphoric ester of chrysin (CP: C(23)H(28)O(10)P(2)) through a simplified Atheron-Todd reaction. Carbon 76-77 carboxypeptidase E Homo sapiens 99-102 15572344-8 2004 Carbon-fiber amperometry was used to assay quantal exocytosis of serotonin (5-HT) from insulin-containing granules following preincubation of INS-1 cells with 5-HT and a precursor. Carbon 0-6 insulin 1 Rattus norvegicus 142-147 15465040-6 2004 CYP2R1 hydroxylated vitamin D(2) at the C-25 position while CYP27A1 hydroxylated it at positions C-24 and C-27. Carbon 40-41 cytochrome P450 family 2 subfamily R member 1 Homo sapiens 0-6 15510304-15 2004 For Se(S(t)Bu)(2) MP2/LANL2DZ(d) geometry optimizations and single point energy calculations revealed a C(2)-symmetric anti- and a C(1) symmetric syn-conformer, the latter being 21 kJ mol(-1) higher in energy than the former. Carbon 104-105 tryptase pseudogene 1 Homo sapiens 18-21 15466158-5 2004 Sfp1 and Sch9 are required for carbon-source modulation of cell size and are regulated at the level of nuclear localization and abundance, respectively. Carbon 31-37 zinc-coordinating transcription factor SFP1 Saccharomyces cerevisiae S288C 0-4 15544474-14 2004 However, there is little qualitative or mechanistic knowledge of the derivatives with substitution at the C-1 carbon of the 5-substituent of pyrimidine nucleosides. Carbon 110-116 heterogeneous nuclear ribonucleoprotein C Homo sapiens 106-109 15544474-16 2004 In the 5-(1-substituted) group of pyrimidine nucleosides, we demonstrated that novel substituents present at the C-1 carbon of the 5-side chain of the pyrimidine nucleosides are important determinants of potent and broad spectrum antiviral (herpes) activity including EBV and HCMV. Carbon 117-123 heterogeneous nuclear ribonucleoprotein C Homo sapiens 113-116 15366059-5 2004 The calculated GIAO RHF shielding constants are sensitive to intramolecular effects: rotation around the C-6-O bond (changes of sigma up to 8 ppm) and conformation at C-2. Carbon 105-106 complement C2 Homo sapiens 167-170 15153069-5 2004 The human COQ2 gene, when expressed in yeast Coq2 null mutant cells, rescued the growth of this yeast strain in the absence of a non-fermentable carbon source and restored CoQ biosynthesis. Carbon 145-151 coenzyme Q2, polyprenyltransferase Homo sapiens 10-14 15362951-1 2004 A new UV filter, the 1-(4-tert-butylphenyl)-2-decanyl-3-(4"-methoxyphenyl)-propane-1,3-dione, called C10-DBM, was prepared by grafting a 10-carbon aliphatic chain to the alpha-carbonyl position of 4-tert-butyl-4"-methoxydibenzoylmethane (BM-DBM), a well-known and often used UV filter. Carbon 140-146 CLLS2 Homo sapiens 105-108 15706950-1 2004 A novel method for the determination of soil organic carbon adsorption coefficients (K(oc)) of pollutants was established using soil column liquid chromatography with stepwise adsorption. Carbon 53-59 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 85-90 15315422-1 2004 The near-IR absorption spectrum of semiconducting single-walled carbon nanotubes is characterized by the transitions associated with the first (S11) and second (S22) pairs of van Hove singularities in the electronic density of states. Carbon 64-70 surface antigen (X-linked) 2 Homo sapiens 144-147 15276161-1 2004 reactions of N(+), N(2)(+), and HCN(+) with CH(4), C(2)H(2), and C(2)H(4). Carbon 44-45 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 32-35 15381006-6 2004 Its (13)C NMR spectrum contained at least 9 C-1 signals, those at delta 108.6 and 107.7 arising from alpha-Araf units. Carbon 8-9 A-Raf proto-oncogene, serine/threonine kinase Homo sapiens 107-111 15296310-7 2004 At approximate 10(-3) of solubility, carbon-normalized distribution coefficients (Koc) were 10-20 times higher than those for absorption to sediment organic matter. Carbon 37-43 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 82-85 15102881-0 2004 Quantifying carbon sources for de novo lipogenesis in wild-type and IRS-1 knockout brown adipocytes. Carbon 12-18 insulin receptor substrate 1 Homo sapiens 68-73 15986678-7 2004 The chemical anchoring efficiency ofpolymerized PEG and phospholipid molecules, which was calculated by the relative carbon ratio of each surface before and after methanol washing using X-ray photoelectron spectroscopy, was 98%. Carbon 117-123 progestagen associated endometrial protein Homo sapiens 48-51 15170356-13 2004 Alternatively, the oxirane undergoes a nucleophilic substitution reaction where the conjugate base of Pro-1 functions as the nucleophile and an acid catalyst polarizes the carbon oxygen bond. Carbon 172-178 lamin A/C Homo sapiens 102-107 15128241-1 2004 Highly substituted oxygen heterocycles can be prepared in good yields at room temperature by reacting o-(1-alkynyl)-substituted arene carbonyl compounds with NBS, I(2), ICl, p-O(2)NC(6)H(4)SCl, or PhSeBr and various alcohols or carbon-based nucleophiles. Carbon 134-140 nibrin Homo sapiens 158-161 15135071-1 2004 Previous studies evidenced in Saccharomyces cerevisiae the activity of a H(+)/glycerol symport, derepressed by growth on non-fermentable carbon sources, later associated with GUP1 and GUP2 genes. Carbon 137-143 O-acyltransferase Saccharomyces cerevisiae S288C 175-179 15135071-1 2004 Previous studies evidenced in Saccharomyces cerevisiae the activity of a H(+)/glycerol symport, derepressed by growth on non-fermentable carbon sources, later associated with GUP1 and GUP2 genes. Carbon 137-143 putative O-acyltransferase Saccharomyces cerevisiae S288C 184-188 15112807-4 2004 A simultaneous transfer of two electrons and cleavage of two C-Cl bonds of CCl4 would completely circumvent chloroform production. Carbon 61-62 C-C motif chemokine ligand 4 Homo sapiens 75-79 15087197-1 2004 Thermal and ozone regenerations of granular activated carbons (GAC) used in the removal of phenol from aqueous solution have been studied. Carbon 54-61 glutaminase Homo sapiens 63-66 15087197-9 2004 For an individual GAC there exits an optimum ozone dose for which phenol is eliminated together with most of its oxidation by-products without incurring in carbon surface chemical alterations. Carbon 156-162 glutaminase Homo sapiens 18-21 28786676-2 2004 It has been found that the eta1-HCO species attached to a Ru atom by a single Ru-C bond is unstable, and that it will convert to more strongly bound eta2- and eta3-HCO surface species. Carbon 33-34 secreted phosphoprotein 1 Homo sapiens 27-31 19342173-2 2009 In this study, the effect of anthraquinone-2,6-disulfonate (AQDS) bound into polypyrrole (PPy) on activated carbon felt (ACF) on anaerobic biodecolorization of azo dyes was investigated and compared with that immobilized on platinum (Pt). Carbon 108-114 ACF Homo sapiens 121-124 19668818-1 2009 We report the first electrochemiluminescent immunosensor combining single-wall carbon nanotube forests with RuBPY-silica-secondary antibody nanoparticles for sensitive detection of cancer biomarker prostate specific antigen. Carbon 79-85 kallikrein related peptidase 3 Homo sapiens 198-223 19238514-10 2009 However, in RA patients the C/G genotype carriers showed higher PAI-1 plasma levels (23.00 +/- 13.81 ng/ml) with respect to C/C (16.77 +/- 11.97 ng/ml) and G/G (10.47 +/- 7.07 ng/ml) genotype carriers (P = 0.036). Carbon 28-29 serpin family E member 1 Homo sapiens 64-69 19572754-4 2009 The relative configuration of the C-15 diastereomers was assigned by (S)-Binol/LAH/EtOH reduction of the corresponding enone. Carbon 34-35 desmoglein 4 Homo sapiens 79-82 19586005-6 2009 Furthermore, the report presents the significance of practical utilization of the recently introduced carbon paste index (denoted as chi(CPE)), which is a qualitative hitherto unused factor based on the evaluation of cyclic voltammograms for standard redox systems (e.g., [Fe(CN)(6)](3-/4-)) and specifying the electrochemical properties of a CPE. Carbon 102-108 carboxypeptidase E Homo sapiens 137-140 19586005-6 2009 Furthermore, the report presents the significance of practical utilization of the recently introduced carbon paste index (denoted as chi(CPE)), which is a qualitative hitherto unused factor based on the evaluation of cyclic voltammograms for standard redox systems (e.g., [Fe(CN)(6)](3-/4-)) and specifying the electrochemical properties of a CPE. Carbon 102-108 carboxypeptidase E Homo sapiens 343-346 19556125-3 2009 We corroborated the importance of the sulfur atom as well as of the n-butyl chain for PPARalpha activity in the 2-mercaptohexanoic acid head group by preparation of carbon analogs and alpha-unsubstituted derivatives. Carbon 165-171 peroxisome proliferator activated receptor alpha Homo sapiens 86-95 33251459-3 2020 It was found that the carbon content of CG was increased by 37.8% from 57.4% (corn flour) to 95.2% (CG). Carbon 22-28 cathepsin G Homo sapiens 100-102 19435638-2 2009 The organic carbon-normalized sorption coefficients (K(OC)) for diuron and phenanthrene (determined from single initial concentrations of 0.8mgL(-1) and 1.5mgL(-1), respectively) were consistently higher following solvent-conditioning of a whole soil with five organic solvents (acetonitrile, acetone, methanol, chloroform and dichloromethane). Carbon 12-18 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 53-58 32898511-10 2020 IL-1beta is increased by LPS and Poly I:C after 1 day, but not by TNFalpha. Carbon 40-41 interleukin 1 alpha Homo sapiens 0-8 19525417-2 2009 The ADE3 gene is known to encode a crucial one-carbon regulon enzyme, tetrahydrofolate synthase, which is involved in the biosynthesis of purine and the amino acids methionine and glycine. Carbon 47-53 trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 Saccharomyces cerevisiae S288C 4-8 31787028-0 2020 Computational investigation reveals Picrasidine C as selective PPARalpha lead: binding pattern, selectivity mechanism and ADME/Tox profile. Carbon 36-49 peroxisome proliferator activated receptor alpha Homo sapiens 63-72 19128878-4 2009 The present work shows that particleboard waste-derived activated carbons (WAC) are efficient adsorbents for the removal of phenol from aqueous solutions, with maximum measured capacities close to 500 mg/g. Carbon 66-73 WW domain containing adaptor with coiled-coil Homo sapiens 75-78 31787028-2 2020 Previously we isolated a dimeric beta-carboline-type alkaloid Picrasidine C from the root of Picrasma quassioides as subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonist. Carbon 62-75 peroxisome proliferator activated receptor alpha Homo sapiens 185-194 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 227-240 peroxisome proliferator activated receptor alpha Homo sapiens 128-137 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 227-240 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 227-240 peroxisome proliferator activated receptor alpha Homo sapiens 128-132 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 227-240 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 227-240 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 19481757-7 2009 Compared with the commercial coated ones (e.g. PDMS, CW/DVB and DVB/CAR/PDMS), the carbon monolith-based fiber had advantages of faster extraction equilibrium and higher extraction capacity due to the superior pore connectivity and pore openness resulting from its bimodal porous substructure. Carbon 83-89 CXADR pseudogene 1 Homo sapiens 68-71 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 227-240 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 227-240 peroxisome proliferator activated receptor alpha Homo sapiens 213-217 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 19578270-3 2009 Intermolecular N-H...O=C interactions form one-dimensional C(4) chains along [010]. Carbon 23-24 complement C4A (Rodgers blood group) Homo sapiens 59-63 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-217 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 19564817-6 2009 RESULTS: We describe for the first time that: (i) PEBP directly interacts with morphine glucuronides (M3G and M6G) but not with morphine, (ii) that the presence of a glucuronide group either on the 3rd or the 6th morphine"s carbon does not affect these interactions, (iii) that M6G binds PEBP in a similar manner as the reference ligand PE and (iv) that PEBP displays a similar affinity for PE, M6G and M3G. Carbon 224-230 phosphatidylethanolamine binding protein 1 Bos taurus 50-54 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-217 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 19402638-0 2009 Suppression of human bone morphogenetic protein signaling by carboxylated single-walled carbon nanotubes. Carbon 88-94 bone morphogenetic protein 1 Homo sapiens 21-47 19417936-4 2009 Further, when the anilido group bears electron-withdrawing substituents, the imino carbon is activated towards nucleophilic attack (as demonstrated by the formation of [2,4-tBu2-6-{CH(NMe2)N-2,4,6-Br3C6H2}-C6H2O]Sn, 4); no such reactivity has been observed when the halo substituents are located on the phenolic ring. Carbon 83-89 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 184-188 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-222 31787028-8 2020 In short, the information obtained from computational strategy would be valuable for us to find more potent, safe and selective PPARalpha agonists during structural optimization.HighlightsThe interactions between PPARalpha and Picrasidine C was thoroughly investigated by means of molecular docking, binding free energy calculation, molecular dynamics simulation.Selectivity mechanism between PPAR isoforms was analyzed with the aim to maintain or improve the selectivity of Picrasidine C depending on the difference between PPARalpha/gamma cavities.The feasibility of Picrasidine C as a subtype-selective lead targeting PPARalpha was investigate to promote the further development of subtype-selective PPARalpha agonists.New analogs of Picrasidine C were designed through core hopping, and were validated through molecular dynamics simulations and MM-GBSA calculation.List of AbbreviationsPPARalpha: Peroxisome proliferator-activated receptor alphaADME/Tox: Absorption, distribution, metabolism, excretion and toxicityPPARs: Peroxisome proliferator-activated receptorsMD: Molecular dynamicsMM-GBSA: Molecular Mechanics Generalized Born Surface AreaSP: Standard precisionPBD: Protein data bankRMSD: Root Mean Square DeviationSPC: Simple point chargeLBFGS: limited-memory Broyden-Fletcher-Goldfarb-ShannoDBD: DNA binding domainPPRE: PPAR-responsive regulatory elementsLBD: Ligand binding domainAF-2: Activating function-2BRL: rosiglitazoneRMSF: Root Mean Square FluctuationtPSA: topological polar surface areaBBB: Blood-brain barrierCNS: Central nervous systemhERG: Human ether-a-go-go gene. Carbon 475-488 peroxisome proliferator activated receptor alpha Homo sapiens 213-217 19420659-5 2009 Results indicate that higher degrees of Pd-carbon contacts for Pd particles embedded in a microporous carbon matrix induce efficient "pumping" of hydrogen out of beta- PdHx. Carbon 43-49 pyruvate dehydrogenase complex component X Homo sapiens 168-172 33178319-10 2020 Moreover, the pathways of central carbon metabolism in cancer and cell cycle related to miR-654-3p and the target genes of PTEN and ATM were found to be different between QXXY patients and GYPXXY patients. Carbon 34-40 phosphatase and tensin homolog Homo sapiens 123-127 19420659-5 2009 Results indicate that higher degrees of Pd-carbon contacts for Pd particles embedded in a microporous carbon matrix induce efficient "pumping" of hydrogen out of beta- PdHx. Carbon 102-108 pyruvate dehydrogenase complex component X Homo sapiens 168-172 19420659-7 2009 In brief, this study highlights that the stability of beta- PdHx phase supported on carbon depends on the degree of contact between Pd and carbon and on the nature of the carbon surface. Carbon 84-90 pyruvate dehydrogenase complex component X Homo sapiens 60-64 19420659-7 2009 In brief, this study highlights that the stability of beta- PdHx phase supported on carbon depends on the degree of contact between Pd and carbon and on the nature of the carbon surface. Carbon 139-145 pyruvate dehydrogenase complex component X Homo sapiens 60-64 19420659-7 2009 In brief, this study highlights that the stability of beta- PdHx phase supported on carbon depends on the degree of contact between Pd and carbon and on the nature of the carbon surface. Carbon 139-145 pyruvate dehydrogenase complex component X Homo sapiens 60-64 19269447-0 2009 Haemoglobin immobilized on nafion modified multi-walled carbon nanotubes for O2, H2O2 and CCl3COOH sensors. Carbon 56-62 C-C motif chemokine ligand 3 Homo sapiens 90-94 33178319-10 2020 Moreover, the pathways of central carbon metabolism in cancer and cell cycle related to miR-654-3p and the target genes of PTEN and ATM were found to be different between QXXY patients and GYPXXY patients. Carbon 34-40 ATM serine/threonine kinase Homo sapiens 132-135 32505912-3 2020 Here, we successfully synthesize the CoP@Ni(OH)2 0.75H2O core-shell nanosheets structure on carbon cloth. Carbon 92-98 caspase recruitment domain family member 16 Homo sapiens 37-40 19381409-7 2009 The X-ray structure of [Au(N--C--N)(Cl)(PPh(3))(2)][PF(6)] confirms that the ligand N--C--N is only sigma-carbon bonded and the PPh(3) molecules are in a trans-arrangement. Carbon 106-112 protein phosphatase 4 catalytic subunit Homo sapiens 40-46 32505912-6 2020 The assembled asymmetric supercapacitor (ASC) of CoP@Ni(OH)2 0.75H2O//activated carbon displays the highest energy density of 33.78 W h kg-1 at 800 W kg-1, as well as the remarkable cycling stability (capacitance retention of 98.5% after 10,000 cycles). Carbon 80-86 caspase recruitment domain family member 16 Homo sapiens 49-52 32989163-8 2020 This work provides a fundamental biochemical rationale for nonredundant roles of these RNA demethylases beyond different substrate preferences and cellular localization, where m6A demethylation by ALKBH5 versus FTO results in release of FA, an endogenous one-carbon unit but potential genotoxin, at different rates in living systems. Carbon 259-265 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 211-214 19203631-5 2009 Other factors, such as the cell secretion time and the immersion time of the multiwalled carbon nanotubes modified glassy carbon electrode (MWCNTs-modified GCE) in the cell eluent, also influenced the intensity of the peak currents. Carbon 89-95 aminomethyltransferase Homo sapiens 156-159 19203631-5 2009 Other factors, such as the cell secretion time and the immersion time of the multiwalled carbon nanotubes modified glassy carbon electrode (MWCNTs-modified GCE) in the cell eluent, also influenced the intensity of the peak currents. Carbon 122-128 aminomethyltransferase Homo sapiens 156-159 32911934-3 2020 In addition, Pd/C was a practical alternative that enabled ligand-free Fukuyama coupling reactions and was efficiently applied to the key C-C bond-forming step to prepare Canagliflozin and Dapagliflozin, which are diabetic SGLT2 inhibitors of current interest. Carbon 16-17 solute carrier family 5 member 2 Homo sapiens 223-228 19109005-0 2009 Hydrogen peroxide biosensor based on the direct electrochemistry of myoglobin immobilized on silver nanoparticles doped carbon nanotubes film. Carbon 120-126 myoglobin Homo sapiens 68-77 19109005-1 2009 A novel H(2)O(2) biosensor has been fabricated based on the direct electrochemistry and electrocatalysis of myoglobin (Mb) immobilized on silver nanoparticles doped carbon nanotubes film with hybrid sol-gel techniques. Carbon 165-171 myoglobin Homo sapiens 108-117 19109005-1 2009 A novel H(2)O(2) biosensor has been fabricated based on the direct electrochemistry and electrocatalysis of myoglobin (Mb) immobilized on silver nanoparticles doped carbon nanotubes film with hybrid sol-gel techniques. Carbon 165-171 myoglobin Homo sapiens 119-121 32911934-3 2020 In addition, Pd/C was a practical alternative that enabled ligand-free Fukuyama coupling reactions and was efficiently applied to the key C-C bond-forming step to prepare Canagliflozin and Dapagliflozin, which are diabetic SGLT2 inhibitors of current interest. Carbon 138-139 solute carrier family 5 member 2 Homo sapiens 223-228 19235974-0 2009 From neutral to anionic eta1-carbon ligands: experimental synthesis and theoretical analysis of a rhodium-yldiide complex. Carbon 29-35 secreted phosphoprotein 1 Homo sapiens 24-28 32600691-0 2020 Fabrication of a sensitive label free electrochemical immunosensor for detection of prostate specific antigen using functionalized multi-walled carbon nanotubes/polyaniline/AuNPs. Carbon 144-150 kallikrein related peptidase 3 Homo sapiens 84-109 19236065-0 2009 Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery. Carbon 72-78 epidermal growth factor Mus musculus 59-62 32600691-1 2020 The aim of this research is to introduce a novel label free electrochemical immunosensor based on glassy carbon electrode (GCE) modified with carboxylated carbon nanotubes (COOH-MWCNTs)/polyaniline (PANI)/gold nanoparticles (AuNPs) for the detection of prostate specific antigen (PSA). Carbon 105-111 kallikrein related peptidase 3 Homo sapiens 253-278 14998337-5 2004 In addition, when a lactam bridge was used as in H-d-Phe-c[Asp-His-d-Phe-Arg-Trp-Lys]-Thr-NH(2) (7, EC(50) = 0.10 nM), the analogue obtained is as potent as alpha-MSH in the frog skin MC1R assay. Carbon 22-23 melanocortin 1 receptor Rattus norvegicus 184-188 32600691-1 2020 The aim of this research is to introduce a novel label free electrochemical immunosensor based on glassy carbon electrode (GCE) modified with carboxylated carbon nanotubes (COOH-MWCNTs)/polyaniline (PANI)/gold nanoparticles (AuNPs) for the detection of prostate specific antigen (PSA). Carbon 105-111 kallikrein related peptidase 3 Homo sapiens 280-283 19170525-6 2009 CPSA of TRX at a carbon electrode is less sensitive and does not discriminate between reduced and oxidized forms of TRX. Carbon 17-23 thioredoxin Homo sapiens 8-11 32707312-5 2020 Carbon catabolite repression and various transcriptional factors such as XlnR, Cre, Clr, Ace, and gna1 control expression of genes encoding cellobiohydrolase (CBH), endoglucanase (EGL) and beta-glucosidase (BGL). Carbon 0-6 doublecortin like kinase 3 Homo sapiens 84-87 19402515-2 2009 The contaminated soil was processed in the microwave field with addition of granular activated carbon (GAC), which was used as strong microwave absorber to enhance microwave heating of the soil mixture to remove the oil contaminant and recover it by a condensation system. Carbon 95-101 glutaminase Homo sapiens 103-106 14685767-0 2004 Transcriptional activators Cat8 and Sip4 discriminate between sequence variants of the carbon source-responsive promoter element in the yeast Saccharomyces cerevisiae. Carbon 87-93 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 27-31 14685767-7 2004 This conclusion is further supported by the finding that biosynthetic derepression of Cat8 in the presence of a nonfermentable carbon source precedes that of Sip4 by about 90 min. Carbon 127-133 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 86-90 32799169-8 2020 Therefore, NSP1 of PRRSV-2 inhibited the mRNA transcription of ccn1 and ccn2 by blocking the ERK-AP-1 axis in Poly I:C stimulated pig macrophages. Carbon 117-118 cellular communication network factor 1 Homo sapiens 63-67 15132331-1 2004 This study describes a fast activated carbon fiber-solid phase microextraction (ACF-SPME) method for determining organochlorine pesticides (OCPs) in water. Carbon 38-44 ACF Homo sapiens 80-83 18996588-0 2009 Sequential delivery of dexamethasone and VEGF to control local tissue response for carbon nanotube fluorescence based micro-capillary implantable sensors. Carbon 83-89 vascular endothelial growth factor A Rattus norvegicus 41-45 32842723-3 2020 The synergism in structural and chemical framework, along with open-ended morphology, enables bifunctionality of hard-carbon NCF as symmetric adsorptive electrodes for supercapacitors and intercalation anodes for hybrid potassium ion capacitors (KICs). Carbon 118-124 neutrophil cytosolic factor 4 Homo sapiens 125-128 18990727-12 2009 We conclude that CYP2E1-mediated metabolism of allylnitrile leads to cyanide release and acute mortality, probably through alpha-carbon hydroxylation, and hypothesize that epoxidation of the beta-gamma double bond by CYP2A5 mediates vestibular toxicity. Carbon 129-135 cytochrome P450, family 2, subfamily e, polypeptide 1 Mus musculus 17-23 15803717-1 2004 Direct electrochemical and electrocatalytic behavior of myoglobin (Mb) immobilized on carbon paste electrode (CPE) by a silica sol-gel film derived from tetraethyl orthosilicate was investigated for the first time. Carbon 86-92 myoglobin Homo sapiens 56-65 15803717-1 2004 Direct electrochemical and electrocatalytic behavior of myoglobin (Mb) immobilized on carbon paste electrode (CPE) by a silica sol-gel film derived from tetraethyl orthosilicate was investigated for the first time. Carbon 86-92 myoglobin Homo sapiens 67-69 32842723-5 2020 Furthermore, NCF as anode in full-cell hybrid KIC (activated carbon as cathode) delivers excellent electrochemical performance with maximum energy and power densities of 57 Wh/kg and 12.5 kW/kg, respectively, when cycled in a potential window of 1.0-4.0 V. The exceptional bifunctional performance of NCF highlights the possibility of utilizing such engineered nanocarbons for high performance energy-storage devices. Carbon 61-67 neutrophil cytosolic factor 4 Homo sapiens 13-16 32842723-5 2020 Furthermore, NCF as anode in full-cell hybrid KIC (activated carbon as cathode) delivers excellent electrochemical performance with maximum energy and power densities of 57 Wh/kg and 12.5 kW/kg, respectively, when cycled in a potential window of 1.0-4.0 V. The exceptional bifunctional performance of NCF highlights the possibility of utilizing such engineered nanocarbons for high performance energy-storage devices. Carbon 61-67 neutrophil cytosolic factor 4 Homo sapiens 301-304 33101846-5 2020 It is shown that FOXO4 directly binds and suppresses the promoters of serine-glycine-one-carbon (SGOC) pathway genes, thereby diminishing SGOC metabolism. Carbon 89-95 forkhead box O4 Homo sapiens 17-22 14960598-5 2004 NMDA-induced accumulation of cytosolic free Ca2+ ([Ca2+]c) was reduced in forebrain neurons from TERT transgenic mice, which was attributable to the rapid flow of [Ca2+]c into the mitochondria from the cytosol without change in Ca2+ influx and efflux through the plasma membrane. Carbon 9-10 telomerase reverse transcriptase Mus musculus 97-101 14744147-4 2004 The structural properties of G-CSF as a function of pH are evaluated in terms of properties such as hydrogen bonding, deviations from X-ray structure, helical/helical packing, and the atomic covariance fluctuation matrix of alpha-carbons. Carbon 230-237 colony stimulating factor 3 Homo sapiens 29-34 14561656-6 2004 However, if VEGF was given locally in the testes of animals pretreated with hCG 4 or 8 h earlier, VEGF acted in synergy with hCG to increase vascular carbon leakage by forming interendothelial cell gaps. Carbon 150-156 vascular endothelial growth factor A Rattus norvegicus 12-16 19064085-1 2009 A polyaniline nanofibers (PAN(nano))/carbon paste electrode (CPE) was prepared via dopping PAN(nano) in the carbon paste. Carbon 37-43 carboxypeptidase E Homo sapiens 61-64 19064085-1 2009 A polyaniline nanofibers (PAN(nano))/carbon paste electrode (CPE) was prepared via dopping PAN(nano) in the carbon paste. Carbon 108-114 carboxypeptidase E Homo sapiens 61-64 19064085-2 2009 The nanogold (Au(nano)) and carbon nanotubes (CNT) composite nanoparticles were bound on the surface of the PAN(nano)/CPE. Carbon 28-34 carboxypeptidase E Homo sapiens 118-121 14561656-6 2004 However, if VEGF was given locally in the testes of animals pretreated with hCG 4 or 8 h earlier, VEGF acted in synergy with hCG to increase vascular carbon leakage by forming interendothelial cell gaps. Carbon 150-156 vascular endothelial growth factor A Rattus norvegicus 98-102 32721313-4 2020 Activated carbon materials were prepared by carbonization and chemical activation using two KOH impregnation ratios, namely 1:1 (ACK1) and 5:1 (ACK5), by mass. Carbon 10-16 tyrosine kinase non receptor 2 Homo sapiens 129-133 14711620-6 2004 JEN1 promoter repression is specific to carbon source; heat or cold shock, osmotic stress, DNA damage, and nitrogen starvation do not significantly affect promoter activity. Carbon 40-46 Jen1p Saccharomyces cerevisiae S288C 0-4 18805949-6 2009 When go1 mutants were shifted from high CO2 to air in light, they accumulated glycolate linearly for 6 h to levels 7-fold higher than wild type and 11-fold higher after 25 h. These studies show that C4 photosynthesis in maize is dependent on photorespiration throughout seedling development and support the view that the carbon oxidation pathway evolved to prevent accumulation of toxic glycolate. Carbon 321-327 glycolate oxidase 1 Zea mays 5-8 32813510-0 2020 Template Construction of Porous CoP/COP2 Microflowers Threaded with Carbon Nanotubes toward High-Efficiency Oxygen Evolution and Hydrogen Evolution Electrocatalysts. Carbon 68-74 caspase recruitment domain family member 16 Homo sapiens 32-35 18434009-1 2008 Activated carbon derived from rattan sawdust (ACR) was evaluated for its ability to remove phenol from an aqueous solution in a batch process. Carbon 10-16 acrosin Homo sapiens 46-49 19053469-3 2008 Here we combined (1)H-detected and (13)C-detected protonless NMR experiments to achieve full assignment of securin"s backbone amide resonances. Carbon 39-40 PTTG1 regulator of sister chromatid separation, securin Homo sapiens 107-114 14709911-6 2004 PAP-I was tolerant of replacement of a carbon atom at the 4-position of the L-pGlu moiety by a sulfur atom (L-OTCA), an oxygen atom (L-2-oxooxazolidine-4-carboxylic acid, L-OOCA) and an NH group (L-2-oxoimidazolidine-4-carboxylic acid, L-OICA). Carbon 39-45 pyroglutamyl-peptidase I Rattus norvegicus 0-5 32906640-1 2020 A carbon nanofiber enriched 8-channel screen-printed electrochemical array was used for the impedimetric detection of SNP related to Factor V Leiden (FV Leiden) mutation, which is the most common inherited form of thrombophilia. Carbon 2-8 coagulation factor V Homo sapiens 133-148 14664572-7 2003 The formation of this organometallacycle proceeds via an intermediate ring-opening product, [Re(O)2(eta1-O-NH)Me], which undergoes [3+2] cycloaddition across the C=C bond of ethylene. Carbon 162-163 secreted phosphoprotein 1 Homo sapiens 100-104 14664572-7 2003 The formation of this organometallacycle proceeds via an intermediate ring-opening product, [Re(O)2(eta1-O-NH)Me], which undergoes [3+2] cycloaddition across the C=C bond of ethylene. Carbon 164-165 secreted phosphoprotein 1 Homo sapiens 100-104 12855560-6 2003 C-18 bound directly to human CCR5, and this interaction was partially competed by the beta-chemokine macrophage inflammatory protein 1 beta (MIP-1 beta) and by HIV-1 R5 gp120. Carbon 0-1 C-C motif chemokine ligand 4 Homo sapiens 141-151 18647136-7 2008 The rate constant of this reaction would be directly related to the strength of the nucleophilic attack of the C-1 hydroxyl group, which depends on the chemical shift of the carbon C-1 (delta(1)) obtained by (13)C-NMR. Carbon 174-180 heterogeneous nuclear ribonucleoprotein C Homo sapiens 111-114 32416394-6 2020 The O-, C-, S-, and Fe-containing functional groups on the surface of MoS2@MBC led to an electrostatic attraction of Cd(II) and strong Cd-S complexation. Carbon 8-9 CDP-diacylglycerol synthase 1 Homo sapiens 135-139 19049460-3 2008 The properties of the carbon complexes as donor ligands were studied by calculating the geometries and bond dissociation energies of the Lewis acid-base adducts with the Lewis acids M(CO)5 (M = Cr, Mo, W), PdCl2SMe2, BH3, BCl3, and Fe2(CO)8. Carbon 22-28 BCL3 transcription coactivator Homo sapiens 222-226 18973384-0 2008 Oxidative conversion of alpha,alpha-disubstituted acetamides to corresponding one-carbon-shorter ketones using hypervalent iodine (lambda5) reagents in combination with tetraethylammonium bromide. Carbon 82-88 immunoglobulin lambda like polypeptide 1 Homo sapiens 131-138 12827295-8 2003 Using a series of polyamine analogues, it was found that the most potent inducers of PAOh1/SMO possessed multiple three-carbon linkers between nitrogens, as typified by N1,N11-bis(ethyl)norspermine. Carbon 120-126 smoothened, frizzled class receptor Homo sapiens 91-94 14578321-11 2003 The correlations (r) between c(2 h) and CNA 2 h postdose were as follows: CsA, r = -0.74; CsA+MMF, r = -0.84; TRL, r = -0.70; TRL+ MMF, r = -0.70 (P <0.001 in all cases). Carbon 4-5 protein phosphatase 3 catalytic subunit beta Homo sapiens 40-45 14597115-2 2003 Both the FAB and ES mass spectra were very similar and showed the presence of ions corresponding to carbon- and oxygen centered spin adducts (DMPO/L*, DMPO/LO*, and DMPO/LOO*). Carbon 100-106 FA complementation group B Homo sapiens 9-12 32574647-1 2020 Fumarylacetoacetate hydrolase (FAH) superfamily members are commonly expressed in the prokaryotic kingdom, where they take part in the committing steps of degradation pathways of complex carbon sources. Carbon 187-193 fumarylacetoacetate hydrolase Homo sapiens 0-29 14622413-10 2003 On the other, the Agc1p, as an aspartate-glutamate exchanger, plays a role within the malate-aspartate NADH shuttle which is critical for the growth of yeast on acetate and fatty acids as carbon sources. Carbon 188-194 citrin Saccharomyces cerevisiae S288C 18-23 32574647-1 2020 Fumarylacetoacetate hydrolase (FAH) superfamily members are commonly expressed in the prokaryotic kingdom, where they take part in the committing steps of degradation pathways of complex carbon sources. Carbon 187-193 fumarylacetoacetate hydrolase Homo sapiens 31-34 32498890-5 2020 Under the optimum conditions, there was a good linear relationship between the degree of fluorescence recovery of carbon dots and DNA concentration in range of 0.0150-9.60 mug mL-1. Carbon 114-120 L1 cell adhesion molecule Mus musculus 176-180 14690236-10 2003 When CCl4 was used as the quencher, the homolytic cleavage of a C-Cl bond of CCl4(T1) occurred to give Cl* and Cl3C* radicals. Carbon 5-6 C-C motif chemokine ligand 4 Homo sapiens 77-81 32872347-4 2020 The effect of chemically grafted carbon fibers on the bond strengths of FMLs was experimentally investigated through lap joint testing. Carbon 33-39 LAP Homo sapiens 117-120 18640024-2 2008 Pd/CNFs modified carbon paste electrode (Pd/CNF-CPE) displayed excellent electrochemical catalytic activities towards dopamine (DA), uric acid (UA) and ascorbic acid (AA). Carbon 17-23 carboxypeptidase E Homo sapiens 48-51 32999831-4 2020 The Co3Fe7@Co5.47N/NCF outperforms commercial platinum/carbon (Pt/C) toward ORR with an onset potential of 1.02 V and a positive half-wave potential of 0.92 V in an alkaline electrolyte (0.59 V in sodium chloride solution), which is ascribed to the unique interfacial structure between Co3Fe7 and Co5.47N supported by 3D N-doped carbon foam to facilitate fast electron and mass transfer. Carbon 55-61 neutrophil cytosolic factor 4 Homo sapiens 19-22 19013524-2 2008 The signalling protein PII, an ancient and widely distributed nitrogen/carbon/ADP/ATP sensor, mediates feedback inhibition relief of NAGK by binding to this enzyme. Carbon 71-77 N-acetylglucosamine kinase Homo sapiens 133-137 32999831-4 2020 The Co3Fe7@Co5.47N/NCF outperforms commercial platinum/carbon (Pt/C) toward ORR with an onset potential of 1.02 V and a positive half-wave potential of 0.92 V in an alkaline electrolyte (0.59 V in sodium chloride solution), which is ascribed to the unique interfacial structure between Co3Fe7 and Co5.47N supported by 3D N-doped carbon foam to facilitate fast electron and mass transfer. Carbon 329-335 neutrophil cytosolic factor 4 Homo sapiens 19-22 18669481-0 2008 Stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Carbon 7-13 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 46-93 32848387-0 2020 Carbon Nanospheres Exert Antitumor Effects Associated with Downregulation of 4E-BP1 Expression on Prostate Cancer. Carbon 0-6 eukaryotic translation initiation factor 4E binding protein 1 Mus musculus 77-83 18669481-1 2008 The aim of this study was to investigate the possible existence and magnitude of stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR). Carbon 88-94 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 127-174 18669481-1 2008 The aim of this study was to investigate the possible existence and magnitude of stable carbon isotope discrimination by human 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR). Carbon 88-94 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 176-180 18682998-1 2008 The fed-batch process using glucose as the sole source of carbon and energy with exponential feeding rate was carried out for high cell density cultivation of recombinant Escherichia coli BL21 (DE3) expressing human granulocyte-colony stimulating factor (hG-CSF). Carbon 58-64 colony stimulating factor 3 Homo sapiens 216-253 32268232-8 2020 Part of the polymer matrix was degraded into soluble organic carbon under simulated sunlight, resulting in continuous Cd2+ release from the pigment particles embedded in the polymer. Carbon 61-67 CD2 molecule Homo sapiens 118-121 19122704-0 2008 Dynamics of laser-ablated carbon plasma: formation of C2 and CN. Carbon 26-32 complement C2 Homo sapiens 54-63 32454326-10 2020 We functionally challenged ovaries in vitro, by polyinosinic:polycytidylic acid (poly I:C) and LPS, known to activate TLR3 and TLR4, respectively, and found a tendency for increased IL-6 production, which was particular evident in the LPS-treated group. Carbon 88-89 toll like receptor 4 Homo sapiens 127-131 18722825-0 2008 Direct electrochemistry and electrochemical catalysis of myoglobin-TiO2 coated multiwalled carbon nanotubes modified electrode. Carbon 91-97 myoglobin Homo sapiens 57-66 18804641-1 2008 An ionic liquid modified carbon paste electrode (IL/CPE) had been fabricated by using hydrophilic ionic liquid 1-amyl-3-methylimidazolium bromide ([AMIM]Br) as a modifier. Carbon 25-31 carboxypeptidase E Homo sapiens 49-55 32751468-0 2020 Mechanism-Independent Manipulation of Single-Wall Carbon Nanotubes with Atomic Force Microscopy Tip. Carbon 50-56 TOR signaling pathway regulator Homo sapiens 96-99 18658273-8 2008 SWCNT inhalation was more effective than aspiration in causing inflammatory response, oxidative stress, collagen deposition, and fibrosis as well as mutations of K-ras gene locus in the lung of C57BL/6 mice. Carbon 0-5 Kirsten rat sarcoma viral oncogene homolog Mus musculus 162-167 32812311-3 2020 Comparisons of experimental and theoretical IR spectra confirmed that both the charge and spin densities of [Y(G/A)Wpi ]+ were delocalized initially at the tryptophan indolyl ring; subsequent formation of the final [Galpha (G/A)W]+ structure gave the highest spin density at the alpha-carbon atom of the N-terminal glycine residue, with a proton solvated by the first amide oxygen atom. Carbon 289-295 succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens 218-224 32775930-4 2020 With a further increase of carbon number, (P 1-2, T 1-2) moves to the lower-pressure and -temperature region and (P 2-3, T 2-3) gradually moves to the lower-pressure and higher-temperature region. Carbon 27-33 prostaglandin E synthase 3 Homo sapiens 114-126 18712874-4 2008 Purified bovine rhodopsin was reconstituted into a series of mono-unsaturated phosphatidylcholines with 14-20 carbons per hydrocarbon chain. Carbon 110-117 rhodopsin Bos taurus 16-25 32874605-3 2020 It was found that sch can be successfully carried by FLG in sch-FLG composite, mainly via the chemical bond of Fe-O-C on the surface of sch-FLG. Carbon 116-117 filaggrin Homo sapiens 53-56 18622131-6 2008 However, for carbon beam therapy, the mean p27 LI significantly decreased from 25.2% before treatment to 18.6% on the 5th day after treatment initiation, followed by a significant increase to 36.1% on the 15th day. Carbon 13-19 interferon alpha inducible protein 27 Homo sapiens 43-46 18622131-9 2008 The changes in p27 LI under carbon beam therapy were significantly different from those under photon beam therapy, which suggests important molecular differences in the radio-biological response between therapies. Carbon 28-34 interferon alpha inducible protein 27 Homo sapiens 15-18 32874605-3 2020 It was found that sch can be successfully carried by FLG in sch-FLG composite, mainly via the chemical bond of Fe-O-C on the surface of sch-FLG. Carbon 116-117 filaggrin Homo sapiens 64-67 32874605-3 2020 It was found that sch can be successfully carried by FLG in sch-FLG composite, mainly via the chemical bond of Fe-O-C on the surface of sch-FLG. Carbon 116-117 filaggrin Homo sapiens 64-67 32760387-0 2020 Expression of Formate-Tetrahydrofolate Ligase Did Not Improve Growth but Interferes With Nitrogen and Carbon Metabolism of Synechocystis sp. Carbon 102-108 MEXAM1_RS01570 Methylobacterium extorquens AM1 14-45 18757823-6 2008 In both MC4100 and MG1655, high ppGpp concentration increased RpoS levels, which in turn reduced growth with poor carbon sources like acetate. Carbon 114-120 RNA polymerase sigma factor RpoS Escherichia coli str. K-12 substr. MG1655 62-66 32760387-5 2020 The formate-tetrahydrofolate ligase (FTL) from Methylobacterium extorquens AM1 was expressed in Synechocystis to enable formate assimilation and reducing the loss of fixed carbon in the photorespiratory pathway. Carbon 172-178 MEXAM1_RS01570 Methylobacterium extorquens AM1 4-35 32760387-5 2020 The formate-tetrahydrofolate ligase (FTL) from Methylobacterium extorquens AM1 was expressed in Synechocystis to enable formate assimilation and reducing the loss of fixed carbon in the photorespiratory pathway. Carbon 172-178 MEXAM1_RS01570 Methylobacterium extorquens AM1 37-40 32760387-10 2020 The data implied that ftl expression interfered with the signaling the carbon/nitrogen ratio in Synechocystis. Carbon 71-77 MEXAM1_RS01570 Methylobacterium extorquens AM1 22-25 32660060-3 2020 Here, we show that a novel small molecule TLR-inhibitor (TAC5) and its derivatives TAC5-a, TAC5-c, TAC5-d, and TAC5-e predominantly antagonized poly(I:C) (TLR3)-, imiquimod (TLR7)-, TL8-506 (TLR8)-, and CpG-oligodeoxynucleotide (TLR9)-induced signaling pathways. Carbon 151-153 toll-like receptor 1 Mus musculus 42-45 18280039-1 2008 Granular activated carbon-supported platinum (Pt/GAC) catalysts were prepared by microwave irradiation and characterized by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD). Carbon 19-25 glutaminase Homo sapiens 49-52 32208333-0 2020 Preparation of C-MOx nanocomposite for efficient adsorption of heavy metal ions via mechanochemical reaction of CaC2 and transitional metal oxides. Carbon 15-16 monooxygenase DBH like 1 Homo sapiens 17-20 18756324-3 2008 CLA can also be acquired by ingestion of supplements, which are usually equimolar mixtures of the c-9,t-11 and t-10,c-12 CLA. Carbon 4-5 complement component 9 Mus musculus 98-101 18498130-9 2008 These data indicate that inadequacies of other 1-carbon vitamins may amplify aberrations of the p53 gene induced by folate depletion alone, implying that concurrent inadequacies in several of these vitamins may have added tumorigenic potential beyond that observed with isolated folate depletion. Carbon 49-55 transformation related protein 53, pseudogene Mus musculus 96-99 32719709-2 2020 This complex trait evolved independently many times, resulting in various realizations of the phenotype, but in all C4 plants the primary fixation of atmospheric carbon is catalyzed by phosphoenolpyruvate carboxylase. Carbon 162-168 phosphoenolpyruvate carboxykinase 1 Homo sapiens 185-216 18694584-1 2008 Removal of selenite from aqueous phase using iron-coated granular activated carbons (GAC) was investigated in this study. Carbon 76-83 glutaminase Homo sapiens 85-88 32220819-0 2020 Volatile-char interactions during biomass pyrolysis: Cleavage of C-C bond in a beta-5 lignin model dimer by amino-modified graphitized carbon nanotube. Carbon 135-141 immunoglobulin kappa variable 2D-26 Homo sapiens 79-85 18601328-6 2008 This study predicts that three collision complexes, c1, c2, and c3, would produce a single final product, 2,4-pentadiynylidyne, HCCCCC(X (2)Pi), C(5)H (p1)+H, via the most stable intermediate, carbon chain HC(5)H (i4). Carbon 193-199 complement C2 Homo sapiens 56-66 18358711-0 2008 Direct electrochemistry of cytochrome c at ordered macroporous active carbon electrode. Carbon 70-76 cytochrome c, somatic Equus caballus 27-39 18358711-1 2008 Three-dimensionally (3D) ordered macroporous active carbon has been fabricated and used as electrode substrate for the direct electrochemistry of horse heart cytochrome c (Cyt c). Carbon 52-58 cytochrome c, somatic Equus caballus 158-170 12954630-3 2003 High expression of wild type C-FADD but not C-FADD with a S194A point mutation arrested the nontumor cell line MCF10A in G2/M but not the tumor cell line MCF7. Carbon 29-30 Fas (TNFRSF6)-associated via death domain Mus musculus 31-35 32092613-0 2020 Silver nanosol SERS quantitative analysis of ultratrace biotin coupled N-doped carbon dots catalytic amplification with affinity reaction. Carbon 79-85 seryl-tRNA synthetase 1 Homo sapiens 15-19 18358711-1 2008 Three-dimensionally (3D) ordered macroporous active carbon has been fabricated and used as electrode substrate for the direct electrochemistry of horse heart cytochrome c (Cyt c). Carbon 52-58 cytochrome c, somatic Equus caballus 172-177 18358711-2 2008 The Cyt c immobilized on the surface of the ordered macroporous active carbon shows a pair of well-defined and nearly reversible redox waves at the formal potential of -0.033V in pH 6.8 phosphate buffer solution. Carbon 71-77 cytochrome c, somatic Equus caballus 4-9 18358711-3 2008 The interaction between Cyt c and the 3D macroporous active carbon makes the formal potential shift negatively compared to that of Cyt c in solution. Carbon 60-66 cytochrome c, somatic Equus caballus 24-29 18358711-3 2008 The interaction between Cyt c and the 3D macroporous active carbon makes the formal potential shift negatively compared to that of Cyt c in solution. Carbon 60-66 cytochrome c, somatic Equus caballus 131-136 18358711-4 2008 Spectrophotometric and electrochemical methods have been used to investigate the interaction between Cyt c and the porous active carbon. Carbon 129-135 cytochrome c, somatic Equus caballus 101-106 18358711-6 2008 A potential application of the Cyt c-immobilized porous carbon electrode as a biosensor to monitor H(2)O(2) has been investigated. Carbon 56-62 cytochrome c, somatic Equus caballus 31-36 12879186-1 2003 This work reports the use of alpha and beta-cyclodextrin-modified carbon paste electrodes (CPE(alpha-CD) and CPE(beta-CD)) to determine simultaneously Pb(II) and Cd(II) by means of the electrochemical technique known as anodic stripping voltammetry (ASV). Carbon 66-72 carboxypeptidase E Homo sapiens 91-94 32151828-0 2020 Preparation of BSA surface imprinted manganese dioxide-loaded tubular carbon fibers with excellent specific rebinding to target protein. Carbon 70-76 albumin Bos taurus 15-18 12805482-5 2003 We next synthesized GSTP1-1-specific inhibitors by elongating the carbon chain of the ethylester at the N-terminal of gamma-glutamyl-S-benzylcysteinyl-phenylglycyl diethylester and performed a pharmacokinetic study on them. Carbon 66-72 glutathione S-transferase pi 1 Homo sapiens 20-27 18374965-6 2008 However, p-nitrophenyl ester of (14)C-palmitic acid specifically labeled bovine ALB, indicating that the micro-environment of the fatty acid-binding domains of DBP and ALB may be different; and DBP may not replace ALB as a transporter of fatty acids. Carbon 36-37 albumin Bos taurus 80-83 18374965-6 2008 However, p-nitrophenyl ester of (14)C-palmitic acid specifically labeled bovine ALB, indicating that the micro-environment of the fatty acid-binding domains of DBP and ALB may be different; and DBP may not replace ALB as a transporter of fatty acids. Carbon 36-37 albumin Bos taurus 168-171 18374965-6 2008 However, p-nitrophenyl ester of (14)C-palmitic acid specifically labeled bovine ALB, indicating that the micro-environment of the fatty acid-binding domains of DBP and ALB may be different; and DBP may not replace ALB as a transporter of fatty acids. Carbon 36-37 albumin Bos taurus 168-171 12845606-4 2003 The transcriptional regulation of ALG2 mRNA levels by carbon source is mainly achieved by glucose repression-derepression, whereas ethanol induction plays only a minor role. Carbon 54-60 GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase Saccharomyces cerevisiae S288C 34-38 32393939-2 2020 The in situ formed LiF and F doped carbon can be functional and beneficial to the battery performance, not only suppressing the "shuttle effect", but also facilitating the electron and ion transportation and accelerating the reaction kinetics. Carbon 35-41 LIF interleukin 6 family cytokine Homo sapiens 19-22 32517148-2 2020 Hexokinase 2 (Hxk2p) is an intracellular glucose sensor that localizes to the cytoplasm or the nucleus depending on the carbon source. Carbon 120-126 hexokinase 2 Saccharomyces cerevisiae S288C 0-12 12721307-4 2003 coq6 mutants are unable to grow on nonfermentable carbon sources and do not synthesize Q but instead accumulate the Q biosynthetic intermediate 3-hexaprenyl-4-hydroxybenzoic acid. Carbon 50-56 putative N,N-dimethylaniline monooxygenase COQ6 Saccharomyces cerevisiae S288C 0-4 12730214-4 2003 Induction of measurable tau fibrillization required an alkyl chain length of at least 12 carbons and a negative charge consisting of carboxylate, sulfonate, or sulfate moieties. Carbon 89-96 microtubule associated protein tau Homo sapiens 24-27 18321683-1 2008 The direct electron-transfer of myoglobin in a new zwitterionic gemini surfactant film with glassy carbon electrode surface has been investigated. Carbon 99-105 myoglobin Homo sapiens 32-41 32517148-2 2020 Hexokinase 2 (Hxk2p) is an intracellular glucose sensor that localizes to the cytoplasm or the nucleus depending on the carbon source. Carbon 120-126 hexokinase 2 Saccharomyces cerevisiae S288C 14-19 18493652-2 2008 We synthesized palmitic acid with carbons C-3 through C-16 perdeuterated, C-1 and C-2 with 13C atoms and hydrogens at C-2. Carbon 34-41 heterogeneous nuclear ribonucleoprotein C Homo sapiens 54-57 32317286-5 2020 An hrr25 mutation results in reduced phosphorylation of Puf3 in vivo and a puf3 deletion mutation reverses growth defects of hrr25 mutant cells grown on medium with a nonfermentable carbon source. Carbon 182-188 serine/threonine protein kinase HRR25 Saccharomyces cerevisiae S288C 125-130 18493652-2 2008 We synthesized palmitic acid with carbons C-3 through C-16 perdeuterated, C-1 and C-2 with 13C atoms and hydrogens at C-2. Carbon 34-41 complement C2 Homo sapiens 82-85 18412341-0 2008 Carbon-deuterium bonds as probes of dihydrofolate reductase. Carbon 0-6 dihydrofolate reductase Homo sapiens 36-59 12906492-0 2003 Evidence of 1D behavior of He4 confined within carbon-nanotube bundles. Carbon 47-53 WAP four-disulfide core domain 2 Homo sapiens 27-30 12906492-1 2003 We present the first low-temperature thermodynamic investigation of the controlled physisorption of He4 gas in carbon single-wall nanotube (SWNT) samples. Carbon 111-117 WAP four-disulfide core domain 2 Homo sapiens 100-103 32105905-1 2020 Carbon -MoS2-x@CdS (C-MoS2-x@CdS) core-shell nanostructures with controlled surface sulfur (S) vacancies were prepared via a glucose assisted hydrothermal growth method. Carbon 0-6 CDP-diacylglycerol synthase 1 Homo sapiens 15-18 12781771-1 2003 Phosphoenolpyruvate carboxylase (PEPC) has a variety of functions in plants, including a major anaplerotic role in replenishing the tricarboxylic acid cycle with intermediates to meet the demand of carbon skeletons for synthesis of organic acids and amino acids. Carbon 198-204 phosphoenolpyruvate carboxykinase 1 Homo sapiens 0-31 12781771-1 2003 Phosphoenolpyruvate carboxylase (PEPC) has a variety of functions in plants, including a major anaplerotic role in replenishing the tricarboxylic acid cycle with intermediates to meet the demand of carbon skeletons for synthesis of organic acids and amino acids. Carbon 198-204 phosphoenolpyruvate carboxykinase 1 Homo sapiens 33-37 18412341-3 2008 We have been developing the use of carbon-deuterium bonds as probes of proteins and now report the application of the technique to the enzyme dihydrofolate reductase, which catalyzes a hydride transfer and has served as a paradigm for biological catalysis. Carbon 35-41 dihydrofolate reductase Homo sapiens 142-165 18412341-8 2008 The results confirm the sensitivity of the carbon-deuterium bonds to their local protein environment, demonstrate that dihydrofolate reductase is electrostatically and dynamically heterogeneous, and lay the foundation for the direct characterization protein electrostatics and dynamics and, potentially, their contribution to catalysis. Carbon 43-49 dihydrofolate reductase Homo sapiens 119-142 17728011-8 2008 L. japonicus nodule carbon metabolism proved to be less sensitive to salinity than in M. truncatula, as enzymatic activities responsible for the carbon supply to the bacteroids to fuel nitrogen fixation, such as sucrose synthase (SS), alkaline invertase (AI), malate dehydrogenase (MDH) and phosphoenolpyruvate carboxylase (PEPC), were less affected by salt than the corresponding activities in barrel medics. Carbon 20-26 malate dehydrogenase, mitochondrial Medicago truncatula 260-280 17728011-8 2008 L. japonicus nodule carbon metabolism proved to be less sensitive to salinity than in M. truncatula, as enzymatic activities responsible for the carbon supply to the bacteroids to fuel nitrogen fixation, such as sucrose synthase (SS), alkaline invertase (AI), malate dehydrogenase (MDH) and phosphoenolpyruvate carboxylase (PEPC), were less affected by salt than the corresponding activities in barrel medics. Carbon 20-26 malate dehydrogenase, mitochondrial Medicago truncatula 282-285 12713337-1 2003 A combined experimental and theoretical investigation at the DFT and MP2 levels on the boron-to-carbon 1,2-shift in "ate species", coming from the quaternization of boranes (A) and boronate (B), is reported. Carbon 96-102 tryptase pseudogene 1 Homo sapiens 69-72 32105905-1 2020 Carbon -MoS2-x@CdS (C-MoS2-x@CdS) core-shell nanostructures with controlled surface sulfur (S) vacancies were prepared via a glucose assisted hydrothermal growth method. Carbon 0-6 CDP-diacylglycerol synthase 1 Homo sapiens 29-32 32374526-2 2020 A single-step strategy is employed for the fabrication of stable 1T-Mnx Mo1- x S2- y Sey and MoFe2 S4- z Sez hierarchical nanosheet arrays on carbon cloth as positive and negative electrodes, respectively. Carbon 142-148 keratin 86 Homo sapiens 68-71 12529326-8 2003 Myc-activated functions are indicative of a physiological state geared toward the rapid utilization of carbon sources, the biosynthesis of precursors for macromolecular synthesis, and the accumulation of cellular mass. Carbon 103-109 MYC proto-oncogene, bHLH transcription factor Homo sapiens 0-3 18227065-10 2008 In VLCAD, these residues are glycines (Gly-175 and Gly-178), allowing the binding channel to extend for an additional 12A and permitting substrate acyl chain lengths as long as 24 carbons to bind. Carbon 180-187 acyl-CoA dehydrogenase very long chain Homo sapiens 3-8 21202271-2 2008 In the crystal structure, inter-molecular C-H O and O-H O hydrogen bonds and C-Cl O close contacts [Cl O = 3.0123 (13) A and C-Cl O = 171.14 (7) ] link the mol-ecules, generating R(2) (2)(16), R(4) (2)(19) and R(4) (4)(22) ring motifs by C(6) chains to form a three-dimensional network. Carbon 42-43 ribonucleotide reductase regulatory subunit M2 Homo sapiens 179-183 21202271-2 2008 In the crystal structure, inter-molecular C-H O and O-H O hydrogen bonds and C-Cl O close contacts [Cl O = 3.0123 (13) A and C-Cl O = 171.14 (7) ] link the mol-ecules, generating R(2) (2)(16), R(4) (2)(19) and R(4) (4)(22) ring motifs by C(6) chains to form a three-dimensional network. Carbon 77-78 ribonucleotide reductase regulatory subunit M2 Homo sapiens 179-183 12600205-5 2003 Mutation of Ser68 to alanine in human AdoMetDC prevents processing by removing the serine side chain necessary for nucleophilic attack at the adjacent carbonyl carbon atom. Carbon 151-157 adenosylmethionine decarboxylase 1 Homo sapiens 38-46 32142918-8 2020 Similar to its family member SHMT2, SHMT1 plays a crucial role in folate-dependent serine/glycine inter-conversion in one-carbon metabolism. Carbon 122-128 serine hydroxymethyltransferase 1 Homo sapiens 36-41 12557274-7 2003 Although PMA2 transcription still remains quite below (20-fold) PMA1 transcription, this is the first environmental condition, identified so far, that leads to a significant PMA2 expression, suggesting that this PM-H(+)-ATPase isoform may play some role during carbon starvation. Carbon 261-267 H(+)-exporting P2-type ATPase PMA2 Saccharomyces cerevisiae S288C 174-178 32142918-10 2020 However, in Drosha-silenced or Drosha low-expressing GC cells, miR-6778-5p positively regulates SHMT1, instead of SHMT2, thus mediating a compensatory activation of cytoplasmic carbon metabolism that plays an essential role in the maintenance of CSCs in gastric cancer (GCSCs). Carbon 177-183 microRNA 6778 Homo sapiens 63-71 18379100-2 2008 The results indicate that the quinones derived from oxidation of 2,5-dihydroxybenzoic acid and 3,4-dihydroxybenzaldehyde participate in Michael addition reactions with 3-hydroxy-1H-phenalene-1-one and via ECE and ECEC mechanisms convert to the different products, with good yield under controlled potential conditions, at carbon electrode. Carbon 322-328 endothelin converting enzyme 1 Homo sapiens 205-208 31995540-6 2020 It was firstly found that the transferred graphite nanoflakes on the contact zone of the silicon tip could be transformed into amorphous carbon layers induced by the shear force and high pressure during the superlubricity tests process. Carbon 137-143 TOR signaling pathway regulator Homo sapiens 97-100 18507150-3 2008 Aspergillus niger Van Tieghem (MTCC 3323) produced polygalacturonase when grown in modified Riviere"s medium containing pectin as single carbon source by fed-batch culture. Carbon 137-143 polygalacturonase Malus domestica 51-68 12420171-8 2002 Carbon derived from the C-1 of acetyl-CoA contained less (13)C than carbon derived from the C-2 of acetyl-CoA, and this difference was attributed to the acetyl-CoA:CO(2) exchange activity of acetyl-CoA synthase. Carbon 0-6 heterogeneous nuclear ribonucleoprotein C Homo sapiens 24-27 12420171-8 2002 Carbon derived from the C-1 of acetyl-CoA contained less (13)C than carbon derived from the C-2 of acetyl-CoA, and this difference was attributed to the acetyl-CoA:CO(2) exchange activity of acetyl-CoA synthase. Carbon 68-74 heterogeneous nuclear ribonucleoprotein C Homo sapiens 24-27 12420171-8 2002 Carbon derived from the C-1 of acetyl-CoA contained less (13)C than carbon derived from the C-2 of acetyl-CoA, and this difference was attributed to the acetyl-CoA:CO(2) exchange activity of acetyl-CoA synthase. Carbon 0-1 heterogeneous nuclear ribonucleoprotein C Homo sapiens 24-27 32314913-0 2020 Metal-Organic Complexes@Melamine Foam Template Strategy to Prepare Three-Dimensional Porous Carbon with Hollow Spheres Structures for Efficient Organic Vapor and Small Molecule Gas Adsorption. Carbon 92-98 gastrin Homo sapiens 177-180 12475962-6 2002 Erg6p catalyzes the methylation of carbon atom 24 in the aliphatic side chain of sterol. Carbon 35-41 sterol 24-C-methyltransferase Saccharomyces cerevisiae S288C 0-5 18275039-5 2008 The maximal effect was achieved at a chain length of four and six carbons, respectively, leading to an activity induction by a factor of 36 for PPARalpha and 18 for PPARgamma, respectively. Carbon 66-73 peroxisome proliferator activated receptor alpha Homo sapiens 144-160 32016283-8 2020 This residual phosphorylation was abolished by Src inhibitors, revealing an unexpected mechanism in which SFKs auto-inhibit their activity by phosphorylating their C-terminal tyrosine residues. Carbon 164-165 Rous sarcoma oncogene Mus musculus 47-50 18206987-4 2008 Mutations in ALDP result in reduced beta-oxidation of very long-chain fatty acids (VLCFA, >22 carbon atoms) in peroxisomes and elevated levels of VLCFA in plasma and tissues. Carbon 94-100 ATP binding cassette subfamily D member 1 Homo sapiens 13-17 12611275-4 2002 A regression study on 10 compounds showed a linear correlation of antiproliferative activity with electronic properties, expressed as the 13C NMR chemical shift for C-4 carbon atom (R2 = 0.97). Carbon 169-175 complement C4A (Rodgers blood group) Homo sapiens 165-168 12611275-6 2002 This finding leads to the expectation that the antiproliferative activity of propargyl thioquinolines can be predicted using the 13C NMR chemical shift value of their C-4 carbon atom. Carbon 171-177 complement C4A (Rodgers blood group) Homo sapiens 167-170 32266903-4 2020 Also, PC3 is found to be an indirect band gap semiconductor in comparison to the zero gap carbon (graphene) and direct gap phosphorous (phosphorene) analogues. Carbon 90-96 chromobox 8 Homo sapiens 6-9 12140287-0 2002 Cytoplasmic compartmentation of Gln3 during nitrogen catabolite repression and the mechanism of its nuclear localization during carbon starvation in Saccharomyces cerevisiae. Carbon 128-134 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 32-36 18056926-6 2008 Treatment with t-10, c-12 CLA reduced TG as well as cellular and secreted adiponectin levels and impaired the assembly of adiponectin oligomers. Carbon 21-22 adiponectin, C1Q and collagen domain containing Mus musculus 74-85 18056926-6 2008 Treatment with t-10, c-12 CLA reduced TG as well as cellular and secreted adiponectin levels and impaired the assembly of adiponectin oligomers. Carbon 21-22 adiponectin, C1Q and collagen domain containing Mus musculus 122-133 12324700-3 2002 In both 3-nitrobenzylidene-3"-iodoaniline and 4-nitrobenzylidene-3"-iodoaniline, (V) and (VI), a combination of C-H...O hydrogen bonds and iodo...nitro interactions generates molecular ladders that are linked into sheets by aromatic pi...pi stacking interactions, while in 2-nitrobenzylidene-4"-iodoaniline and 3-nitrobenzylidene-4"-iodoaniline, (VII) and (VIII), which both crystallize with Z" = 2 in C2/c and P1, respectively, the combination of C-H...O hydrogen bonds and iodo...nitro interactions generates sheets, which in (VIII) are further linked by pi...pi stacking interactions to form a three-dimensional structure. Carbon 112-113 complement C2 Homo sapiens 402-413 32212664-1 2020 Transition metal-nitrogen/carbon (TM-N/C) materials are promising alternatives to Pt-based oxygen reduction reaction (ORR) electrocatalysts of fuel cells. Carbon 26-32 STT3 oligosaccharyltransferase complex catalytic subunit A Homo sapiens 34-40 18184736-11 2008 Thus, a putative metabolon involving PEPC and PDC(pl) could function to channel carbon from phosphoenolpyruvate to acetyl-coenzyme A and/or to recycle CO(2) from PDC(pl) to PEPC. Carbon 80-86 LOC8259391 Ricinus communis 37-41 18184736-11 2008 Thus, a putative metabolon involving PEPC and PDC(pl) could function to channel carbon from phosphoenolpyruvate to acetyl-coenzyme A and/or to recycle CO(2) from PDC(pl) to PEPC. Carbon 80-86 LOC8259391 Ricinus communis 173-177 18218972-11 2008 From our phenotypic and genetic characterizations, we propose a model whereby TDY1 and TDY2 function together in a single genetic pathway, possibly in homo- and heteromeric complexes, to promote carbon export from leaves. Carbon 195-201 callose synthase Zea mays 87-91 18207151-4 2008 This means FAMEs within a carbon chain length, having up to six double bonds, elute before the next (one carbon longer) saturated FAME elutes. Carbon 26-32 benign adult familial myoclonic epilepsy 1 Homo sapiens 11-15 18207151-4 2008 This means FAMEs within a carbon chain length, having up to six double bonds, elute before the next (one carbon longer) saturated FAME elutes. Carbon 105-111 benign adult familial myoclonic epilepsy 1 Homo sapiens 11-15 18082128-6 2008 Carbon from glucose and pyruvate were rapidly incorporated into many lipid classes in INS-1 cells. Carbon 0-6 insulin 1 Rattus norvegicus 86-91 18065618-7 2008 However, when the Ath1p-dependent mobilization of trehalose identified in this study was impaired, glycogen was mobilized earlier and faster, indicating a fine-tuning control in carbon storage management during periods of carbon and energy restriction. Carbon 178-184 alpha,alpha-trehalase ATH1 Saccharomyces cerevisiae S288C 18-23 18065618-7 2008 However, when the Ath1p-dependent mobilization of trehalose identified in this study was impaired, glycogen was mobilized earlier and faster, indicating a fine-tuning control in carbon storage management during periods of carbon and energy restriction. Carbon 222-228 alpha,alpha-trehalase ATH1 Saccharomyces cerevisiae S288C 18-23 18784799-1 2008 Grasses using the C(4) photosynthetic pathway dominate today"s savanna ecosystems and account for approximately 20% of terrestrial carbon fixation. Carbon 131-137 complement C4A (Rodgers blood group) Homo sapiens 18-22 18071229-3 2007 The as-prepared gold nanoparticles attached glassy carbon electrode (Au/GCE) presented excellent catalytic ability toward the oxidation of nitrite. Carbon 51-57 aminomethyltransferase Homo sapiens 72-75 18029478-3 2007 Serine hydroxymethyltransferase (SHMT) catalyzes the interconversion of glycine and serine, another 1-carbon donor. Carbon 102-108 serine hydroxymethyltransferase 1 Homo sapiens 0-31 18029478-3 2007 Serine hydroxymethyltransferase (SHMT) catalyzes the interconversion of glycine and serine, another 1-carbon donor. Carbon 102-108 serine hydroxymethyltransferase 1 Homo sapiens 33-37 17924615-2 2007 The structures of two representative nonpolar metabolites were identified earlier as dimers of 17beta-estradiol linked through a diaryl ether bond between the C-3 phenolic oxygen of one molecule and the C-2 or C-4 aromatic carbon of another. Carbon 223-229 complement C4A (Rodgers blood group) Homo sapiens 210-213 17975075-0 2007 New insights into the regulation of the Saccharomyces cerevisiae UGA4 gene: two parallel pathways participate in carbon-regulated transcription. Carbon 113-119 Uga4p Saccharomyces cerevisiae S288C 65-69 17975075-7 2007 Analysis of the expression and subcellular localization of the transcription factors that regulate UGA4 as well as partial deletions and site-directed mutations of the UGA4 promoter region suggested that there are two parallel pathways that act in regulating this gene by the carbon source. Carbon 276-282 Uga4p Saccharomyces cerevisiae S288C 99-103 17975075-7 2007 Analysis of the expression and subcellular localization of the transcription factors that regulate UGA4 as well as partial deletions and site-directed mutations of the UGA4 promoter region suggested that there are two parallel pathways that act in regulating this gene by the carbon source. Carbon 276-282 Uga4p Saccharomyces cerevisiae S288C 168-172 17914763-5 2007 Carbon-13 MAS NMR, X-ray diffraction, and differential scanning calorimetry (DSC) of polycrystalline c-1 and s-1 racemates are also reported. Carbon 0-6 heterogeneous nuclear ribonucleoprotein C Homo sapiens 101-104 17660359-8 2007 Homologues of FEA1 and FRE1 were identified previously as high-CO(2)-responsive genes, HCR1 and HCR2, in Chlorococcum littorale, suggesting that components of the iron assimilation pathway are responsive to carbon nutrition. Carbon 207-213 uncharacterized protein Chlamydomonas reinhardtii 14-18 17660359-8 2007 Homologues of FEA1 and FRE1 were identified previously as high-CO(2)-responsive genes, HCR1 and HCR2, in Chlorococcum littorale, suggesting that components of the iron assimilation pathway are responsive to carbon nutrition. Carbon 207-213 uncharacterized protein Chlamydomonas reinhardtii 23-27 17514507-1 2007 Very long-chain acyl-CoA dehydrogenase (VLCAD) catalyses the initial step of mitochondrial beta-oxidation of long-chain fatty acids with a chain length of 14 to 20 carbons. Carbon 164-171 acyl-CoA dehydrogenase very long chain Homo sapiens 0-38 17514507-1 2007 Very long-chain acyl-CoA dehydrogenase (VLCAD) catalyses the initial step of mitochondrial beta-oxidation of long-chain fatty acids with a chain length of 14 to 20 carbons. Carbon 164-171 acyl-CoA dehydrogenase very long chain Homo sapiens 40-45 17408600-0 2007 The conformation of the C-glycosyl analogue of N-acetyl-lactosamine in the free state and bound to a toxic plant agglutinin and human adhesion/growth-regulatory galectin-1. Carbon 24-25 galectin 1 Homo sapiens 161-171 17368933-1 2007 The treatment of 2,4,5-trichlorobiphenyl (PCB29) in simulated soil-washing solution by granular activated carbon (GAC) adsorption and microwave (MW) regeneration was investigated in this study. Carbon 106-112 glutaminase Homo sapiens 114-117 17640273-4 2007 Specifically, mutations and conditions resulting in fructose-6-phosphate (F-6-P) accumulation elicit superinduction of uspA upon carbon starvation, whereas genetic manipulations reducing the pool size of F-6-P have the opposite effect. Carbon 129-135 putative universal stress protein UspA Escherichia coli 119-123 17640273-8 2007 Indeed, we show that uspA is, in fact, induced before the carbon source is depleted from the medium. Carbon 58-64 putative universal stress protein UspA Escherichia coli 21-25 17270373-0 2007 Effect of fiber length of carbon nanotubes on the absorption of erythropoietin from rat small intestine. Carbon 26-32 erythropoietin Rattus norvegicus 64-78 17270373-1 2007 Erythropoietin (EPO) loaded carbon nanotubes (CNTs) with surfactant as an absorption enhancer were prepared for the oral delivery of EPO using two types of CNTs, long and short fiber length CNTs, and the effect of CNT fiber length on the absorption efficiency of EPO was studied. Carbon 28-34 erythropoietin Rattus norvegicus 0-14 17431629-3 2007 In plants, two chloroplastic TRXs, named TRX f and TRX m, were originally identified as light dependent regulators of several carbon metabolism enzymes including Calvin cycle enzymes. Carbon 126-132 thioredoxin Homo sapiens 29-32 17431629-3 2007 In plants, two chloroplastic TRXs, named TRX f and TRX m, were originally identified as light dependent regulators of several carbon metabolism enzymes including Calvin cycle enzymes. Carbon 126-132 thioredoxin Homo sapiens 41-44 17488134-2 2007 A conductive atomic force tip is used to collect carbon from a glassy carbon substrate and redeposit it onto a gold thin film under voltage control. Carbon 49-55 TOR signaling pathway regulator Homo sapiens 26-29 17488134-2 2007 A conductive atomic force tip is used to collect carbon from a glassy carbon substrate and redeposit it onto a gold thin film under voltage control. Carbon 70-76 TOR signaling pathway regulator Homo sapiens 26-29 17461576-4 2007 X-ray studies of the solid-state structures show that the six compounds contain eta1-Cp" ligands, with linear or almost linear C-Hg-Cl or C-Hg-C coordination environments. Carbon 85-86 secreted phosphoprotein 1 Homo sapiens 80-84 17461576-4 2007 X-ray studies of the solid-state structures show that the six compounds contain eta1-Cp" ligands, with linear or almost linear C-Hg-Cl or C-Hg-C coordination environments. Carbon 127-128 secreted phosphoprotein 1 Homo sapiens 80-84 17461576-4 2007 X-ray studies of the solid-state structures show that the six compounds contain eta1-Cp" ligands, with linear or almost linear C-Hg-Cl or C-Hg-C coordination environments. Carbon 127-128 secreted phosphoprotein 1 Homo sapiens 80-84 17485668-4 2007 We show that nanoparticles (copolymer particles, cerium oxide particles, quantum dots, and carbon nanotubes) enhance the probability of appearance of a critical nucleus for nucleation of protein fibrils from human beta(2)-microglobulin. Carbon 91-97 beta-2-microglobulin Homo sapiens 214-235 17233767-3 2007 Moreover, Gpr1p is subjected to phosphorylation at serine-37 in a carbon source-dependent manner. Carbon 66-72 Gpr1p Saccharomyces cerevisiae S288C 10-15 17461623-7 2007 The analysis of the spectra has revealed the existence of two different isomers for both CH(3)D(+) and CD(3)H(+), which differ in the bond length between the carbon atom and the unique ligand atom. Carbon 158-164 CD247 molecule Homo sapiens 103-109 17404303-8 2007 In contrast, poly(I:C) treatment significantly protected TLR3(-/-) mice from lethal challenge despite some deficiencies in cytokine induction. Carbon 20-21 toll-like receptor 3 Mus musculus 57-61 17432928-8 2007 The authors report a mathematical model of the G1 to S network that newly takes into account nucleo/cytoplasmic localization, the role of the cyclin-dependent kinase Sic1 in facilitating nuclear import of its cognate Cdk1-Clb5, Whi5 control, and carbon source regulation of Sic1 and Sic1-containing complexes. Carbon 246-252 cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1 Saccharomyces cerevisiae S288C 166-170 17432928-8 2007 The authors report a mathematical model of the G1 to S network that newly takes into account nucleo/cytoplasmic localization, the role of the cyclin-dependent kinase Sic1 in facilitating nuclear import of its cognate Cdk1-Clb5, Whi5 control, and carbon source regulation of Sic1 and Sic1-containing complexes. Carbon 246-252 cyclin-dependent serine/threonine-protein kinase CDC28 Saccharomyces cerevisiae S288C 217-221 17349072-8 2007 This study demonstrates that decreased homocysteinaemia by CEE therapy parallels with increased genomic DNA methylation, suggesting a potential new candidate mechanism by which ERT affects the risk of cancers and a possible new candidate biomarker for the oestrogen-related carcinogenesis through folate-related one-carbon metabolism. Carbon 316-322 E74 like ETS transcription factor 3 Homo sapiens 177-180 17292862-1 2007 CYP27A1 catalyzes vitamin D(3) 25-hydroxylation and further hydroxylation at C-1alpha, C-24 or C-26(27). Carbon 77-78 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 0-7 17292862-1 2007 CYP27A1 catalyzes vitamin D(3) 25-hydroxylation and further hydroxylation at C-1alpha, C-24 or C-26(27). Carbon 77-78 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 0-7 17388280-10 2007 One of the C-F bonds is found to eclipse the C-S bond in the B3LYP calculations, while the MP2 calculations predict a slight deviation and the HF calculations a large deviation from the eclipsed position, as the corresponding F-C-C-S dihedral angle is calculated to be 0.9 degrees (MP2) and 27.6 degrees (HF). Carbon 11-12 tryptase pseudogene 1 Homo sapiens 282-285 17410784-7 2007 The changes observed in the C-1s NEXAFS spectra coincided with an increasing removal of organic carbon from the dissolved phase with increasing total metal concentrations. Carbon 96-102 heterogeneous nuclear ribonucleoprotein C Homo sapiens 28-31 17477046-1 2007 On the basis of ab initio MP2 and semi-empirical PM3 quantum-chemical calculations the bistability of the nonplanar O=C-N-H fragment in the structure of simple amides and dipeptides is discussed. Carbon 118-119 tryptase pseudogene 1 Homo sapiens 26-29 17324000-1 2007 We report on the direct visualization of chirality changes in carbon nanotubes by mapping local changes in resonant RBM phonon frequencies with an optical resolution of 40 nm using near-field Raman spectroscopy. Carbon 62-68 RNA binding motif protein Y-linked family 2 member D, pseudogene Homo sapiens 116-119 17355867-3 2007 Here, we provide novel insight into the functional motions underlying Pin1 substrate interaction using nuclear magnetic resonance deuterium ((2)D) and carbon ((13)C) spin relaxation. Carbon 151-157 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens 70-74 20641465-1 2004 It is a selective 5-HT1A antagonist radiotracer labeled with (11)C, a positron emitter with a physical t1/2 of 20.4 min (2). Carbon 64-66 5-hydroxytryptamine receptor 1A Homo sapiens 18-24 17279653-8 2007 Carbon impurities induce, during PdHx decomposition, creation of an organized network of cracks which divides the continuous film into separated domains. Carbon 0-6 pyruvate dehydrogenase complex component X Homo sapiens 33-37 17846567-3 2007 The detection of the low energy conformation of O=C-N-phenethyl segment in solution allowed the correlation of the NMR data with the configuration of newly stereogenic carbon C-2; thus, one diastereomer was labeled SS while the other was RS. Carbon 50-51 complement C2 Homo sapiens 175-178 17198417-1 2007 Cu(PPh3)3(TCNE) (TCNE = tetracyanoethylene) and 14 other examples form [TCNE]22- dimers possessing a long 2.89 +/- 0.05 A two-electron four-center (2e-/4c) C-C bond in the solid state. Carbon 0-1 protein phosphatase 4 catalytic subunit Homo sapiens 3-7 17194077-1 2007 Interconversion of carbon sites in boat-chair-boat (BCB) cyclodecane occurs by way of the twist-boat-chair (TBC) conformation, which predicts that C-1 exchanges with C-4, etc. Carbon 19-25 heterogeneous nuclear ribonucleoprotein C Homo sapiens 147-150 17194077-1 2007 Interconversion of carbon sites in boat-chair-boat (BCB) cyclodecane occurs by way of the twist-boat-chair (TBC) conformation, which predicts that C-1 exchanges with C-4, etc. Carbon 19-25 complement C4A (Rodgers blood group) Homo sapiens 166-169 17041184-9 2007 An unusual phenotype of the pex1 and pex6 mutants was that they grew poorly with glucose as the carbon source, but nearly wild type with galactose, which suggested impaired hexokinase function and that C. neoformans peroxisomes might function analogously to the glycosomes of the trypanosomid parasites. Carbon 96-102 peroxisomal biogenesis factor 1 Mus musculus 28-32 17928372-9 2007 A significant number of genes up-regulated in id1 mutant immature leaves have potential roles in photosynthesis and carbon fixation, substantiating a possible connection between floral induction and assimilate partitioning. Carbon 116-122 indeterminate growth 1 Zea mays 46-49 17199340-2 2006 Here the authors demonstrate using an advanced version QMPFF3 how the problem of insufficient accuracy of the MP2-based training set for the aromatic carbon atom type can be effectively solved by a simple model correction using state-of-the-art CCSD(T) data. Carbon 150-156 tryptase pseudogene 1 Homo sapiens 110-113 16904332-1 2006 The nature of C-5 substituent and the configuration at C-5 carbon of 2,3-diphenyltetrahydrofurans, with chiral centres at C-2, C-3 and C-5, show a remarkable influence on their COX-2 inhibition and selectivity. Carbon 59-65 complement C5 Homo sapiens 14-17 16904332-1 2006 The nature of C-5 substituent and the configuration at C-5 carbon of 2,3-diphenyltetrahydrofurans, with chiral centres at C-2, C-3 and C-5, show a remarkable influence on their COX-2 inhibition and selectivity. Carbon 59-65 complement C5 Homo sapiens 55-58 16904332-1 2006 The nature of C-5 substituent and the configuration at C-5 carbon of 2,3-diphenyltetrahydrofurans, with chiral centres at C-2, C-3 and C-5, show a remarkable influence on their COX-2 inhibition and selectivity. Carbon 59-65 complement C2 Homo sapiens 122-130 16904332-1 2006 The nature of C-5 substituent and the configuration at C-5 carbon of 2,3-diphenyltetrahydrofurans, with chiral centres at C-2, C-3 and C-5, show a remarkable influence on their COX-2 inhibition and selectivity. Carbon 59-65 complement C5 Homo sapiens 55-58 16830357-7 2006 Through MS2 and MS3 studies of a synthetic peptide standard AGHKLL and its chemically labeled and isotope-encoded forms, we discovered that the water loss from the b(3) ion involves the carbonyl group of His, the hydrogen connected to the alpha-carbon of Gly, and the amide hydrogen of His. Carbon 186-192 MS2 Homo sapiens 8-11 17083213-0 2006 Symmetric and unsymmetric "dumbbells" of Ru2-alkynyl units via C-C bond formation reactions. Carbon 63-64 doublecortin domain containing 2 Homo sapiens 41-44 17083213-0 2006 Symmetric and unsymmetric "dumbbells" of Ru2-alkynyl units via C-C bond formation reactions. Carbon 65-66 doublecortin domain containing 2 Homo sapiens 41-44 17064377-0 2006 Identification of YhdA as a regulator of the Escherichia coli carbon storage regulation system. Carbon 62-68 hypothetical protein Escherichia coli 18-22 17243231-3 2006 Activated carbon was placed in solutions of pH 1, 5, or 7, and the leaching of six cations (cadmium, chromium, copper, nickel, lead, and zinc) and two anions (arsenate and selenate) was recorded. Carbon 10-16 alanine--glyoxylate and serine--pyruvate aminotransferase Homo sapiens 44-48 12372858-4 2002 The key reaction involved one-step remote oxyfunctionalization of unactivated methine carbons at C-17 of CDCA and at C-14 of UDCA as their methyl ester-peracetate derivatives with dimethyldioxirane (DMDO). Carbon 86-93 cytokine like 1 Homo sapiens 97-101 12322761-9 2002 In addition to ozonation, filtration with granular activated carbon (GAC) was very effective in removing pharmaceuticals. Carbon 61-67 glutaminase Homo sapiens 69-72 12587744-3 2002 Isolate K10 gave the maximum biosurfactant production in medium A (containing kerosene as a sole carbon source) as compared to medium B (containing glucose as a sole carbon source). Carbon 97-103 keratin 10 Homo sapiens 8-11 12587744-3 2002 Isolate K10 gave the maximum biosurfactant production in medium A (containing kerosene as a sole carbon source) as compared to medium B (containing glucose as a sole carbon source). Carbon 166-172 keratin 10 Homo sapiens 8-11 12175241-3 2002 It was constructed anticipating an intramolecular displacement of the carbon (C17)-oxygen (O4) bond (see product 48). Carbon 70-76 cytokine like 1 Homo sapiens 78-81 12162964-6 2002 The superposition of the alpha-carbon atoms of the liganded (complexed with retinol) and unliganded forms of zebrafish CRBP shows significant differences in correspondence of the betaC-betaD (residues 55-58) and betaE-betaF (residues 74-77) turns, providing evidence for the occurrence of conformational changes accompanying retinol binding/release. Carbon 31-37 retinol binding protein 2a, cellular Danio rerio 119-123 12190533-4 2002 Nonlinear dielectric effect measurements for CCl4 and aniline in activated carbon fibers (pore width 1.4 nm) show divergence at these transitions, confirming the hexatic phase. Carbon 75-81 C-C motif chemokine ligand 4 Homo sapiens 45-49 12188352-2 2002 Stable carbon isotope fractionation associated with permanganate oxidation of trichloroethylene (TCE), tetrachloroethylene (PCE), and cis-1,2-dichloroethylene (cDCE) has been measured, to study the possibility of applying stable carbon isotope analysis as a technique to assess the efficacy of remediation implemented by permanganate oxidation. Carbon 7-13 suppressor of cytokine signaling 1 Homo sapiens 134-139 12211644-14 2002 In comparison with C group, AOP significantly (p < 0.05) increased with Vit group. Carbon 19-20 vitrin Rattus norvegicus 75-78 12163655-2 2002 The present study was undertaken to assess the effect of elevated plasma total homocysteine caused by cystathionine beta-synthase deficiency on one-carbon metabolism in 10 homozygous mutant mice and 10 age- and sex-matched wild-type mice. Carbon 148-154 cystathionine beta-synthase Mus musculus 102-129 12177326-5 2002 Targeted disruption of NCIB-nahR by homologous recombination resulted in a growth defect in the presence of naphthalene or salicylate as sole carbon and energy source. Carbon 142-148 NahR Pseudomonas putida 28-32 12079452-2 2002 Crystal data for C(17)H(13)ClN(3)O(3)Re: space group, orthorhombic, Pbca; a = 12.713(6) A; b = 15.103(7) A; c = 18.253(8) A; Z = 8. Carbon 0-1 PBCA Homo sapiens 68-72 12135569-2 2002 Bacterial PII is regulated by covalent modification and binding to effector molecules in response to the nitrogen/carbon status of the cell and appropriately coordinates the activity of glutamine synthetase and the transcription of a nitrogen sensitive regulon. Carbon 114-120 hypothetical protein Arabidopsis thaliana 186-206 12027680-1 2002 Aiming at a synthesis of spiro[2.4]hepta-4,6-dienes with a carbon substituent at C-4, we investigated solvolysis reactions of the thiatricycle 2, obtained from spiro[2.4]hepta-4,6-diene (1) and thiophosgene by [4 + 2] cycloaddition. Carbon 59-65 complement C4A (Rodgers blood group) Homo sapiens 81-84 12033297-0 2002 Direct electrochemistry of cytochrome c at a glassy carbon electrode modified with single-wall carbon nanotubes. Carbon 52-58 cytochrome c, somatic Equus caballus 27-39 12033297-0 2002 Direct electrochemistry of cytochrome c at a glassy carbon electrode modified with single-wall carbon nanotubes. Carbon 95-101 cytochrome c, somatic Equus caballus 27-39 12033297-1 2002 The electrochemistry of horse heart cytochrome c was studied by cyclic voltammetry at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs). Carbon 95-101 cytochrome c, somatic Equus caballus 36-48 12033297-1 2002 The electrochemistry of horse heart cytochrome c was studied by cyclic voltammetry at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs). Carbon 138-144 cytochrome c, somatic Equus caballus 36-48 12028803-6 2002 Moreover, HO-1 expression was positively correlated to the higher organic carbon (OC) and polyaromatic hydrocarbons (PAHs) content of fine versus coarse PM, as well as the rise in PAH content that occurs in coarse PM during the winter months. Carbon 74-80 heme oxygenase 1 Homo sapiens 10-14 11997969-1 2002 The soil sorption coefficient Kd and the soil organic carbon sorption coefficient KOC of pesticides are basic parameters used by environmental scientists and regulatory agencies worldwide in describing the environmental fate and behavior of pesticides. Carbon 54-60 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 82-85 12054566-4 2002 SPT3 and SNF2 activated GDH1 expression on either carbon source whereas GCN5 played no role in any condition tested. Carbon 50-56 glutamate dehydrogenase (NADP(+)) GDH1 Saccharomyces cerevisiae S288C 24-28 11912240-11 2002 There is considerable evidence for a GDH shunt to return the carbon in amino acids back into reactions of carbon metabolism and the tri-carboxylic acid cycle. Carbon 61-67 glutamate dehydrogenase 1 Homo sapiens 37-40 11912240-11 2002 There is considerable evidence for a GDH shunt to return the carbon in amino acids back into reactions of carbon metabolism and the tri-carboxylic acid cycle. Carbon 106-112 glutamate dehydrogenase 1 Homo sapiens 37-40 11983932-2 2002 We have generated a model of the human GALR1 galanin receptor subtype (hGALR1) based on the alpha carbon maps of frog rhodopsin and investigated the significance of potential contact residues suggested by the model using site-directed mutagenesis. Carbon 98-104 galanin receptor 1 Homo sapiens 39-44 11983932-2 2002 We have generated a model of the human GALR1 galanin receptor subtype (hGALR1) based on the alpha carbon maps of frog rhodopsin and investigated the significance of potential contact residues suggested by the model using site-directed mutagenesis. Carbon 98-104 galanin receptor 1 Homo sapiens 71-77 11944694-11 2002 The CsF/CaO/Si system exhibited the complete destruction of CF4 at as low as 600 degrees C. The solid product analysis by X-ray diffraction (XRD) showed the formation of CaF2 and the depletion of Si with black carbon particles formed in the solid reagent residue. Carbon 210-216 colony stimulating factor 2 Homo sapiens 4-7 11805079-2 2002 Free radical attack on the nucleotidyl C-1" carbon yields 2-deoxyribonolactone (dL) as a significant lesion. Carbon 44-50 heterogeneous nuclear ribonucleoprotein C Homo sapiens 39-42 12108627-3 2002 It was also found that the helicity of the lactam moiety in investigated oxacephams and clavams is controlled by the absolute configuration at the C-6 and C-5 carbon atom, respectively. Carbon 159-165 complement C5 Homo sapiens 155-158 11948019-5 2002 The optimal side-chain length for the inhibition of steroid sulfatase activity was found to be six carbons, which corresponds to the number of carbons that mimic the B, C and D steroid rings, between C6 and C17. Carbon 99-106 cytokine like 1 Homo sapiens 207-210 12188024-1 2002 The HOMO energies and the charges on the aromatic carbons of two sets of MAO-A-inhibiting phenylisopropylamines, one containing 4-amino substituents, were calculated by the AM1 method, in order to evaluate the importance of charge-transfer interactions between drug and enzyme. Carbon 50-57 monoamine oxidase A Homo sapiens 73-78 11741859-9 2002 This is in contrast to Saccharomyces cerevisiae, where Cat8p and Sip4p, homologs of FacB, regulate PEPCK as well as the expression of other genes necessary for growth on nonfermentable carbon sources in response to the carbon source present. Carbon 185-191 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 55-60 11741859-9 2002 This is in contrast to Saccharomyces cerevisiae, where Cat8p and Sip4p, homologs of FacB, regulate PEPCK as well as the expression of other genes necessary for growth on nonfermentable carbon sources in response to the carbon source present. Carbon 219-225 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 55-60 11562373-7 2001 Analysis of the relative levels of these proteins revealed that the expression of GDH1 and GDH3 is differentially regulated and depends on the nature of the carbon source. Carbon 157-163 glutamate dehydrogenase (NADP(+)) GDH1 Saccharomyces cerevisiae S288C 82-86 11601984-3 2001 The interactions of chicken liver basic fatty acid-binding protein (Lb-FABP) with 1-(13)C-enriched palmitic acid (PA) and oleic acid (OA) were investigated by (13)C NMR spectroscopy. Carbon 88-89 liver basic fatty acid binding protein Gallus gallus 68-75 11594802-2 2001 T(h)-symmetrical P8(C=C)6, 1, is predicted to be a remarkably stable small heterofullerene with carbon atoms less pyramidal than in C60. Carbon 96-102 NADH:ubiquinone oxidoreductase subunit A9 Homo sapiens 17-25 11594840-2 2001 Treatment of the allenyl sulfoxides and sulfones possessing a proper delta-hydroxy appendage at the C-1 position with potassium tert-butoxide effected endo mode ring closure at the sp-hybridized carbon center of the allenyl moiety to provide the five- to eight-membered oxacycles in high yields. Carbon 195-201 heterogeneous nuclear ribonucleoprotein C Homo sapiens 100-103 11596746-6 2001 For LAS, the organic carbon-based partition coefficient values were between 2.4 x 10(3) and 6.6 x 10(5)L/kg for the C10 and C13 homologues, respectively; these values are similar to those obtained from laboratory tests for the sorption of LAS onto marine sediments. Carbon 21-27 lipoic acid synthetase Homo sapiens 4-7 11543681-2 2001 Saturation of the double bond between C-17 and C-20 of fusidic acid produces four stereoisomers differing in the configuration at C-17 and C-20. Carbon 38-39 cytokine like 1 Homo sapiens 130-134 11543681-2 2001 Saturation of the double bond between C-17 and C-20 of fusidic acid produces four stereoisomers differing in the configuration at C-17 and C-20. Carbon 47-48 cytokine like 1 Homo sapiens 130-134 11585064-0 2001 Organic carbon flow in the Ob, Yenisey Rivers and Kara Sea of the Arctic region. Carbon 8-14 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 55-58 11585064-3 2001 The coupled measurements were carried out to assess possible connectivity between organic carbon flow into the Kara Sea and transport of radioactive nuclides in this marine environment. Carbon 90-96 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 116-119 11585064-4 2001 Organic carbon flow into the Kara Sea is influenced significantly by terrigenous sources carried by the Ob and Yenisey Rivers. Carbon 8-14 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 34-37 11525404-0 2001 Carbon source-dependent transcriptional regulation of the QCR8 gene in Kluyveromyces lactis. Carbon 0-6 ubiquinol--cytochrome-c reductase subunit 8 Saccharomyces cerevisiae S288C 58-62 11525404-2 2001 The QCR8 gene of the yeast K1uyveromyces lactis is transcriptionally regulated by the carbon source in the growth medium. Carbon 86-92 ubiquinol--cytochrome-c reductase subunit 8 Saccharomyces cerevisiae S288C 4-8 11525404-3 2001 Deletion analysis of the KlQCR8 promoter shows that an element located between -144 bp and -113 bp specifically controls induction of QCR8 gene expression on non-fermentable carbon sources. Carbon 174-180 ubiquinol--cytochrome-c reductase subunit 8 Saccharomyces cerevisiae S288C 27-31 11279158-11 2001 As observed in other yeast coq mutants, supplementation of growth media with Q(6) rescues the abc1/coq8 null mutants for growth on nonfermentable carbon sources. Carbon 146-152 protein kinase COQ8 Saccharomyces cerevisiae S288C 94-98 11279158-11 2001 As observed in other yeast coq mutants, supplementation of growth media with Q(6) rescues the abc1/coq8 null mutants for growth on nonfermentable carbon sources. Carbon 146-152 protein kinase COQ8 Saccharomyces cerevisiae S288C 99-103 11320327-1 2001 Contrary to the expectation of chemists, the first X-ray structures of carbon monoxide bound to myoglobin (Mb) showed a highly distorted Fe-C-O bond system. Carbon 0-1 myoglobin Homo sapiens 96-105 17020349-2 2006 The synthesis is characterized by the stereoselective construction of the quaternary amino carbon center at C8a by an asymmetric transferring Strecker synthesis and the highly efficient conversion of cyanohydrin 4 to 1 via intramolecular cyclization reactions. Carbon 91-97 complement C8 alpha chain Homo sapiens 108-111 16982895-7 2006 The additional two mannoses in PIM4, relative to PIM2, are located at the distal 6" carbon of the alpha1-alpha6-linked mannose and would project away from the CD1d binding groove for interaction with the TCR. Carbon 84-90 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6 Mus musculus 98-111 17020589-8 2006 In addition, growth on non-fermentable carbon sources relocates a portion of Msn5p to the cytoplasm and leads to a partial nuclear accumulation of Ssa4p. Carbon 39-45 karyopherin MSN5 Saccharomyces cerevisiae S288C 77-82 17020589-8 2006 In addition, growth on non-fermentable carbon sources relocates a portion of Msn5p to the cytoplasm and leads to a partial nuclear accumulation of Ssa4p. Carbon 39-45 Hsp70 family chaperone SSA4 Saccharomyces cerevisiae S288C 147-152 11305908-3 2001 Cytoplasmic SHMT (cSHMT) has been postulated to channel one-carbon substituted folates to various folate-dependent enzymes, and alternative splicing of the cSHMT transcript may be a mechanism that enables specific protein-protein interactions. Carbon 60-66 serine hydroxymethyltransferase 1 Homo sapiens 18-23 32322443-5 2020 Compared with the CK treatment, cumulative mineralization and potential mineralized organic carbon content of C1, C2 and C3 increased by 71.79%-183.86% and 71.08%-173.33%. Carbon 92-98 heterogeneous nuclear ribonucleoprotein C Homo sapiens 110-123 11456964-2 2001 The resulting six-membered open face is puckered, with two of the cage carbons (C6 and C9) occupying the low-coordinate cage positions above the plane of the four remaining atoms (C5, B7, B8, and B10). Carbon 71-78 complement C5 Homo sapiens 180-199 11322734-5 2001 Reactivity of the polysaccharide C-atoms was determined by 13C NMR spectroscopy: For dextran this was C-3 > C-2 > C-4, while for pullulan it was C-6 > C-3 > C-2 > C-4. Carbon 33-34 complement C2 Homo sapiens 111-114 11322734-5 2001 Reactivity of the polysaccharide C-atoms was determined by 13C NMR spectroscopy: For dextran this was C-3 > C-2 > C-4, while for pullulan it was C-6 > C-3 > C-2 > C-4. Carbon 33-34 complement C4A (Rodgers blood group) Homo sapiens 120-123 11322734-5 2001 Reactivity of the polysaccharide C-atoms was determined by 13C NMR spectroscopy: For dextran this was C-3 > C-2 > C-4, while for pullulan it was C-6 > C-3 > C-2 > C-4. Carbon 33-34 complement C2 Homo sapiens 169-172 11322734-5 2001 Reactivity of the polysaccharide C-atoms was determined by 13C NMR spectroscopy: For dextran this was C-3 > C-2 > C-4, while for pullulan it was C-6 > C-3 > C-2 > C-4. Carbon 33-34 complement C4A (Rodgers blood group) Homo sapiens 178-181 16930051-0 2006 Reactions of endo-3-diazotricyclo[3.2.1.0 2,4]oct-6-ene, a potential precursor for the generation of a neutral C8H8 molecule with a pyramidally coordinated carbon. Carbon 156-162 mannosidase endo-alpha Homo sapiens 13-17 16930051-2 2006 According to B3LYP/6-311+G(d,p) computations, the corresponding carbene endo-7 easily produces the highly strained neutral C8H8 compound 4 comprising a pyramidally tetracoordinated carbon which then rearranges to bridgehead alkene 15 through a cascade of rearrangements. Carbon 181-187 mannosidase endo-alpha Homo sapiens 72-76 32186875-6 2020 Here, we synthesize continuous and homogenous films of two differ-ent all carbon linked 3D porous aromatic frameworks with nanometer precision thickness (PAF-1 and BCMP-2). Carbon 74-80 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 154-159 16914311-9 2006 Central to these new renditions is the hypothesis that the appropriate P-450 introduces dioxygen into the precursor yielding either: A, a 20 peroxy sterol species or B, a species oxygenated at both C-17 and C-20 or C, a species oxygenated at both C-20 and C-21. Carbon 0-1 cytokine like 1 Homo sapiens 198-202 11352531-6 2001 The carbon sources capable of inducing JEN1 transcription were dependent on the strain. Carbon 4-10 Jen1p Saccharomyces cerevisiae S288C 39-43 11179732-7 2001 The preferred conformations, inferred from an analysis of (13)C-NMR characteristics, notably the chemical shift of C-17 in a series of analogs, to have the tertiary alcohol (1"-hydroxy-1"-methylethyl) substituent equatorial on the cyclohexane chair, are confirmed by molecular modeling. Carbon 62-63 cytokine like 1 Homo sapiens 115-119 32318537-0 2020 The Functionalized Single-Walled Carbon Nanotubes Gas Sensor With Pd Nanoparticles for Hydrogen Detection in the High-Voltage Transformers. Carbon 33-39 gastrin Homo sapiens 50-53 11237251-4 2001 Furthermore, in AdoCbl, this upward folding of the corrin is accompanied by increases in the carbon-cobalt bond length and in the Co-C-C bond angle (which are also less pronounced in Ado(Im)Cbl), and which indicate that the Co-C bond is indeed destabilized by this mechanism. Carbon 93-99 Cbl proto-oncogene Homo sapiens 19-22 11237251-4 2001 Furthermore, in AdoCbl, this upward folding of the corrin is accompanied by increases in the carbon-cobalt bond length and in the Co-C-C bond angle (which are also less pronounced in Ado(Im)Cbl), and which indicate that the Co-C bond is indeed destabilized by this mechanism. Carbon 130-131 Cbl proto-oncogene Homo sapiens 19-22 11237251-4 2001 Furthermore, in AdoCbl, this upward folding of the corrin is accompanied by increases in the carbon-cobalt bond length and in the Co-C-C bond angle (which are also less pronounced in Ado(Im)Cbl), and which indicate that the Co-C bond is indeed destabilized by this mechanism. Carbon 130-131 Cbl proto-oncogene Homo sapiens 19-22 11237251-9 2001 Stretching the Co-C bond to simulate the approach to the transition state was found to result in an upward folding of the corrin ring, a slight decrease in the axial Co-N bond length, a slight displacement of the metal atom from the plane of the equatorial nitrogens towards the "lower" axial ligand, and a decrease in strain energy amounting to about 8 kcal mol(-1) for both AdoCbl and Ado(Im)Cbl. Carbon 15-16 Cbl proto-oncogene Homo sapiens 379-382 16442717-10 2006 Carbon "C1" of the highest surface area (520.66 m(2)/g) and calcium content (333.3 mg/l) has the highest adsorptive capacity for removal of Cr(III). Carbon 0-6 heterogeneous nuclear ribonucleoprotein C Homo sapiens 8-11 32318537-1 2020 Single-walled carbon nanotubes (SWCNTs) have been widely discussed and applied as novel gas sensing nanomaterials. Carbon 14-20 gastrin Homo sapiens 88-91 31864051-0 2020 Removal of sulfamethoxazole in water by electro-enhanced Co2+/peroxydisulfate system with activated carbon fiber-cathode. Carbon 100-106 complement C2 Homo sapiens 57-60 16677817-7 2006 A comparison of the relative inhibitory activities of the two groups of regioisomers investigated shows that the regioisomers in which the alkyl substituent is attached to the same olefinic carbon atom (C-2) as the para-methanesulfonylphenyl moiety generally exhibit a greater potency with respect to COX-2 inhibition. Carbon 190-196 complement C2 Homo sapiens 203-206 16895344-1 2006 In this report, we compare the toxicological effects between pure carbon multiwalled nanotubes (MWNTs) and N-doped multiwalled carbon (CNx) nanotubes. Carbon 127-133 calnexin Mus musculus 135-138 11134339-1 2001 In Saccharomyces cerevisiae the subcellular distribution of Bcy1 is carbon source dependent. Carbon 68-74 cAMP-dependent protein kinase regulatory subunit BCY1 Saccharomyces cerevisiae S288C 60-64 11134339-2 2001 In glucose-grown cells, Bcy1 is almost exclusively nuclear, while it appears more evenly distributed between nucleus and cytoplasm in carbon source-derepressed cells. Carbon 134-140 cAMP-dependent protein kinase regulatory subunit BCY1 Saccharomyces cerevisiae S288C 24-28 31372715-11 2020 This suggests that higher cytosolic activity of AMPK is required for the utilization of an alternative carbon source in gsp1-1894 cells. Carbon 103-109 Ran GTPase GSP1 Saccharomyces cerevisiae S288C 120-124 11153271-14 2001 Lipoate synthase, which catalyzes the formation of two C-S bonds from octanoic acid, has a very high sequence similarity with biotin synthase. Carbon 55-56 lipoic acid synthetase Homo sapiens 0-16 16707085-2 2006 The catalytic action of the LNW/CPE on the oxidation of MFA via one-electron and one-proton transfer is attributed to the formation of the porous construction and the increase of efficient surface of the electrode due to the adulteration of LNW with carbon powders. Carbon 250-256 carboxypeptidase E Homo sapiens 32-35 31828877-3 2020 For this purpose, biotinilated-anti-prostate-specific antigen (PSA) antibody was bioconjugated with iron oxide magnetic nanoparticles (Fe3 O4 ) and drop-casted on the surface of glassy carbon electrode (GCE). Carbon 185-191 aminopeptidase puromycin sensitive Homo sapiens 18-67 16952839-1 2006 The thermal inactivation of immobilized lipase from Candida antarctica in 1-alcohols with four to eight carbons at various temperatures could be well expressed using a model in which heterogeneity in the susceptibility of the enzyme to the inactivation was assumed. Carbon 104-111 PAN0_003d1715 Moesziomyces antarcticus 40-46 11061974-1 2000 EST2 is a novel thermophilic carboxylesterase, isolated and cloned from Alicyclobacillus (formerly Bacillus) acidocaldarius, which optimally hydrolyses esters with acyl chain lengths of six to eight carbon atoms at 70 degrees C. On the basis of the amino acid sequence homology, it has been classified as a member of the mammalian hormone-sensitive lipase (HSL) subfamily. Carbon 199-205 telomerase reverse transcriptase Homo sapiens 0-4 11054825-4 2000 However, disruption of YDL077c (also known as VAM6) exhibited an slow growth phenotype in minimal media and also in rich media containing glycerol as a carbon source. Carbon 152-158 VPS39 subunit of HOPS complex Homo sapiens 46-50 31831247-0 2020 Potential fate of wetland soil carbon in a deltaic coastal wetland subjected to high relative sea level rise. Carbon 31-37 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 94-97 11065123-1 2000 Stimulation of group I metabotropic glutamate receptors (mGluR 1 and 5) activates G-protein coupled-phospholipase C (PLC) to release 1,2-diacylglycerol (DAG) and arachidonic acid (ArAc). Carbon 114-115 glutamate receptor, metabotropic 1 Mus musculus 57-70 16686531-3 2006 Subsequent SAR studies have revealed that the phenoxy and phenylsulfanyl analogues of 6c, 3-(1-carboxy-4-mercaptobutoxy)benzoic acid 26a and 3-[(1-carboxy-4-mercaptobutyl)thio]benzoic acid 26b, also possess potent inhibitory activities toward GCP II. Carbon 86-88 folate hydrolase 1 Rattus norvegicus 243-249 31831247-5 2020 This erosion and degradation of wetland soil carbon stores demonstrates the potential impact of rising sea levels on the future fate of coastal wetland carbon and atmospheric CO2 levels. Carbon 45-51 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 103-106 31831247-5 2020 This erosion and degradation of wetland soil carbon stores demonstrates the potential impact of rising sea levels on the future fate of coastal wetland carbon and atmospheric CO2 levels. Carbon 152-158 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 103-106 11001219-6 2000 The appearance of the des-tyrosine (des-Tyr) Leu-enkephalin, which cannot be detected directly at a carbon electrode, was monitored using the on-capillary complexation technique. Carbon 100-106 prodynorphin Homo sapiens 45-59 31580782-0 2020 Pre-programmed Tri-layer Electro-Thermal Actuators Composed of Shape Memory Polymer and Carbon Nanotubes. Carbon 88-94 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 15-18 16541428-4 2006 The HF values show quite a different tendency to MP2, and even in the CBS limit they are far from experiment for not only the isotropic shielding of carbonyl carbon but also most shielding anisotropies. Carbon 149-155 tryptase pseudogene 1 Homo sapiens 49-52 16524873-1 2006 Phosphoenolpyruvate carboxylase (PEPC, EC 4.1.1.31) is believed to play a significant role in supporting nitrogen fixation via anaplerotic CO2 fixation for recycling carbon in nodules. Carbon 166-172 LjPEPC1 Lotus japonicus 0-31 10972830-6 2000 This regulation by the carbon substrates is subordinate to the activity of the complex Hap2/3/4/5p, which counteracts the negative effect of the URS1 element. Carbon 23-29 transcription activator HAP2 Saccharomyces cerevisiae S288C 87-98 16524873-1 2006 Phosphoenolpyruvate carboxylase (PEPC, EC 4.1.1.31) is believed to play a significant role in supporting nitrogen fixation via anaplerotic CO2 fixation for recycling carbon in nodules. Carbon 166-172 LjPEPC1 Lotus japonicus 33-37 32041777-3 2020 PQBP1 uses its C-terminal YxxPxxVL motif for binding to the splicing factor thioredoxin like 4A (TXNL4A), but the biological function of this interaction has yet to be elucidated. Carbon 15-16 thioredoxin like 4A Homo sapiens 76-95 16524873-10 2006 The data are discussed in terms of a role for PEPC in the carbon/nitrogen metabolic flux in nodules. Carbon 58-64 LjPEPC1 Lotus japonicus 46-50 16626117-1 2006 Highly substituted 1H-isochromenes, isobenzofurans, and pyranopyridines can be prepared by allowing o-(1-alkynyl)arenecarboxaldehydes and ketones to react with I2, ICl, NIS, Br2, NBS, p-O2NC6H4SCl, or PhSeBr and various alcohols or carbon-based nucleophiles at room temperature. Carbon 232-238 nibrin Homo sapiens 179-182 10920257-6 2000 The low affinity of homarine (N-methylpicolinate) for oxidized DAO, as in the case of o-methylbenzoate, is due to steric hindrance: one of the ortho carbons of benzoate is near the phenol carbons of Tyr228 and the other ortho carbon is near the carbonyl oxygen of Gly313. Carbon 149-156 D-amino acid oxidase Homo sapiens 63-66 10920257-6 2000 The low affinity of homarine (N-methylpicolinate) for oxidized DAO, as in the case of o-methylbenzoate, is due to steric hindrance: one of the ortho carbons of benzoate is near the phenol carbons of Tyr228 and the other ortho carbon is near the carbonyl oxygen of Gly313. Carbon 188-195 D-amino acid oxidase Homo sapiens 63-66 32041777-3 2020 PQBP1 uses its C-terminal YxxPxxVL motif for binding to the splicing factor thioredoxin like 4A (TXNL4A), but the biological function of this interaction has yet to be elucidated. Carbon 15-16 thioredoxin like 4A Homo sapiens 97-103 10920257-6 2000 The low affinity of homarine (N-methylpicolinate) for oxidized DAO, as in the case of o-methylbenzoate, is due to steric hindrance: one of the ortho carbons of benzoate is near the phenol carbons of Tyr228 and the other ortho carbon is near the carbonyl oxygen of Gly313. Carbon 149-155 D-amino acid oxidase Homo sapiens 63-66 32221723-0 2020 DNAzyme-functionalized porous carbon nanospheres serve as a fluorescent nanoprobe for imaging detection of microRNA-21 and zinc ion in living cells. Carbon 30-36 microRNA 21 Homo sapiens 107-118 16491495-1 2006 A new series of hydrocarbon cages containing hexa- and octacoordinate carbon centers were designed theoretically by performing DFT calculations at the B3 LYP/6-311+G** level. Carbon 21-27 hexosaminidase subunit alpha Homo sapiens 45-49 32221723-1 2020 The present study shows that a dual-signal nanoprobe consisting of DNAzyme-functionalized porous carbon nanospheres (PCNs) responds to microRNA-21 and zinc ion (Zn2+). Carbon 97-103 microRNA 21 Homo sapiens 135-146 10877783-1 2000 The microbial ecology of anaerobic carbon oxidation processes was investigated in Black Sea shelf sediments from mid-shelf with well-oxygenated bottom water to the oxic-anoxic chemocline at the shelf-break. Carbon 35-41 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 88-91 32221723-6 2020 Graphical abstract Schematic representation of the DNAzyme-functionalized porous carbon nanospheres for the imaging analysis of microRNA-21 and Zn2+ in living cells. Carbon 81-87 microRNA 21 Homo sapiens 128-139 32068404-3 2020 Here, we generated and characterized the Hsp90 inhibitor PU-H71, conjugated to the mitochondrial delivery vehicle triphenylphosphonium (TPP) with a C10 carbon spacer, named SMTIN-C10, to enable dual binding to orthosteric and allosteric sites. Carbon 152-158 heat shock protein 90 alpha family class A member 1 Homo sapiens 41-46 10858308-3 2000 In contrast, the antiarthritis drug D-penicillamine, D-PEN, which differs from D-Cys only by the presence of two methyl groups on the beta-carbon, inhibits ZnCPD by promoting the release of the active-site zinc. Carbon 139-145 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 55-58 16823915-5 2006 The predominant subclass was IgG1 although higher levels of IgG2a were observed as the carbon chain length of AGs increased. Carbon 87-93 immunoglobulin heavy variable V1-9 Mus musculus 60-65 32273832-7 2020 After exposure to 0.05 to 1 Gy of carbon ions and 0.5 to 4 Gy of X-rays, only IGFBP-3 showed obvious increase with increased doses, both carbon ions and X-rays. Carbon 34-40 insulin like growth factor binding protein 3 Homo sapiens 78-85 16213557-2 2006 PCB-contaminated soil was treated in a quartz reactor by microwave irradiation at 2450MHz with the addition of granular activated carbon (GAC). Carbon 130-136 glutaminase Homo sapiens 138-141 16539510-0 2006 Evolution of the electronic properties of metallic single-walled carbon nanotubes with the degree of CCl2 covalent functionalization. Carbon 65-71 C-C motif chemokine ligand 2 Homo sapiens 101-105 16539510-1 2006 The changes in energetic, structural, and electronic properties of the metallic (5,5) single-walled carbon nanotube (SWNT) with the degree of sidewall covalent functionalization of CCl(2) are investigated extensively by using density functional theory calculations. Carbon 100-106 C-C motif chemokine ligand 2 Homo sapiens 181-186 16600673-3 2006 The identified and localized chemical species were: sodium, potassium, phosphocholine, cholesterol and galactosylceramide (GalC) with carbon chain lengths C18:0 (N-stearoyl-galactosylceramide) and C24:0 (N-lignoceroylgalactosylceramide) with CH24:0 (hydroxy-lignoceroylgalactosylceramide). Carbon 134-140 galactosylceramidase Rattus norvegicus 123-127 16711607-4 2006 The transesterified palm oil was found to contain methyl esters of up to C32 carbon atoms. Carbon 77-83 chemokine like factor Homo sapiens 73-76 16711607-5 2006 In the very long chain FAME with carbon numbers > or = 20, both even and odd carbon numbers accounted for 0.26 wt%, with C24 and C26 being the major ones present in the residue after short-path distillation of transesterified palm oil. Carbon 33-39 benign adult familial myoclonic epilepsy 1 Homo sapiens 23-27 16711607-5 2006 In the very long chain FAME with carbon numbers > or = 20, both even and odd carbon numbers accounted for 0.26 wt%, with C24 and C26 being the major ones present in the residue after short-path distillation of transesterified palm oil. Carbon 80-86 benign adult familial myoclonic epilepsy 1 Homo sapiens 23-27 16253352-3 2006 The results showed (a) CD-1 mice to have a well-developed olfactory sensitivity for aliphatic aldehydes which for the majority of substances is higher than that of other mammalian species, (b) a limited concentration range of about 1 log unit from threshold to near saturation which is similar to that shown at the single receptor cell level, (c) no significant correlation between perceptibility in terms of olfactory detection thresholds and carbon chain length of the aldehydes tested, and (d) no systematic effect of preexposure to an aldehyde on sensitivity. Carbon 444-450 CD1 antigen complex Mus musculus 23-27 16332379-8 2006 Cortisol response to CRH tended to be higher in CS than PS across all days, and by day 29 cortisol response to CRH was significantly higher in CS compared to PS and tended to be higher in C than PS. Carbon 0-1 corticotropin releasing hormone Sus scrofa 21-24 16478127-1 2006 Covalent adduct chemical ionization (CACI) using a product of acetonitrile self-reaction, (1-methyleneimino)-1-ethenylium (MIE; CH2=C=N+=CH2), has been investigated as a method for localizing double bonds in a series of 16 non-methylene-interrupted fatty acid methyl esters (NMI-FAME) of polyenes with three and more double bonds. Carbon 0-1 benign adult familial myoclonic epilepsy 2 Homo sapiens 279-283 16478127-3 2006 [M + 54]+ ions of several 20- and 22-carbon FAME that include one double bond in the C2-C3 position separated by two to five methylene units from a three, four, or five C homoallylic system dissociated according to rules for the homoallylic system, with an additional fragment corresponding to cleavage between the lone double bond and the carboxyl group and defining the position of the lone double bond. Carbon 37-43 benign adult familial myoclonic epilepsy 2 Homo sapiens 44-48 16467472-3 2006 Microarray experiments showed that Azf1 activates nonoverlapping gene sets in different carbon sources: in glucose, Azf1 activates carbon and energy metabolism genes, and in glycerol-lactate, Azf1 activates genes needed for cell wall maintenance. Carbon 88-94 Azf1p Saccharomyces cerevisiae S288C 35-39 16467472-3 2006 Microarray experiments showed that Azf1 activates nonoverlapping gene sets in different carbon sources: in glucose, Azf1 activates carbon and energy metabolism genes, and in glycerol-lactate, Azf1 activates genes needed for cell wall maintenance. Carbon 88-94 Azf1p Saccharomyces cerevisiae S288C 116-120 16467472-3 2006 Microarray experiments showed that Azf1 activates nonoverlapping gene sets in different carbon sources: in glucose, Azf1 activates carbon and energy metabolism genes, and in glycerol-lactate, Azf1 activates genes needed for cell wall maintenance. Carbon 88-94 Azf1p Saccharomyces cerevisiae S288C 116-120 16467472-3 2006 Microarray experiments showed that Azf1 activates nonoverlapping gene sets in different carbon sources: in glucose, Azf1 activates carbon and energy metabolism genes, and in glycerol-lactate, Azf1 activates genes needed for cell wall maintenance. Carbon 131-137 Azf1p Saccharomyces cerevisiae S288C 35-39 16467472-3 2006 Microarray experiments showed that Azf1 activates nonoverlapping gene sets in different carbon sources: in glucose, Azf1 activates carbon and energy metabolism genes, and in glycerol-lactate, Azf1 activates genes needed for cell wall maintenance. Carbon 131-137 Azf1p Saccharomyces cerevisiae S288C 116-120 16467472-3 2006 Microarray experiments showed that Azf1 activates nonoverlapping gene sets in different carbon sources: in glucose, Azf1 activates carbon and energy metabolism genes, and in glycerol-lactate, Azf1 activates genes needed for cell wall maintenance. Carbon 131-137 Azf1p Saccharomyces cerevisiae S288C 116-120 16826926-5 2006 The present paper emphasized to summarize the headway of application research of SERS in the late years, along with the introduction of some work in our lab, especially, as a new field, on Fullerenes thin film and carbon nano-tube materials. Carbon 214-220 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 81-85 16396963-5 2006 This stimulation was caused by a change in the fate of the substrate carbon skeletons resulting from an increase in the activities and mRNA levels of the key gluconeogenic enzymes that are common to lactate, glutamine, and glycerol metabolism, i.e., mainly of phosphoenolpyruvate carboxykinase and, to a lesser extent, of glucose-6-phosphatase and fructose-1,6-bisphosphatase. Carbon 69-75 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 322-343 16199256-6 2006 C1q binds directly to carbon nanotubes. Carbon 22-28 complement C1q A chain Homo sapiens 0-3 16289480-0 2006 Structural-activity relationship study on C-4 carbon atom of the CB1 antagonist SR141716: synthesis and pharmacological evaluation of 1,2,4-triazole-3-carboxamides. Carbon 46-52 complement component 4B (Chido blood group) Mus musculus 42-45 16541957-0 2006 An efficient synthesis of acyclic N7- and N9-adenine nucleosides via alkylation with secondary carbon electrophiles to introduce versatile functional groups at the C-1 position of acyclic moiety. Carbon 95-101 heterogeneous nuclear ribonucleoprotein C Homo sapiens 164-167 16939097-4 2006 The reactor with granular activated carbon (GAC) had a better performance; efficiencies higher than 95% were obtained at loads up to 17 kg m(-3)d(-1) and higher than 80% with loads up to 26 kg m(-3)d(-1). Carbon 36-42 glutaminase Homo sapiens 44-47 16343610-2 2005 Chemical and spectroscopic analyses indicated that ACDP-2 is a highly branched arabinogalactan polymer that composes of linked d-galactopyranose and d-glucopyranose, which contains predominantly a branching point at the 6-carbon. Carbon 222-228 cyclin M2 Mus musculus 51-57 16323874-1 2005 [reaction: see text] B3LYP/6-31G(d) and MP2 calculations predict interactions between the divalent carbon and one double bond in tricyclo[3.2.2.0(2,4)]nona-6,8-dien-3-ylidene (3). Carbon 99-105 tryptase pseudogene 1 Homo sapiens 40-43 16305240-10 2005 Collectively, these observations provide direct evidence that enzymatic Co-C bond activation involves stabilization of the post-homolysis product, Co2+ Cbl, rather than destabilization of the Co3+ Cbl "ground" state. Carbon 0-1 Cbl proto-oncogene Homo sapiens 152-155 16224807-2 2005 Two complementary one-pot three-component Mannich-type and Reformatsky-type synthetic strategies have been developed for the construction of chiral 3-amino propanoate fragments (eventually bis-substituted at C-2) directly linked to the anomeric carbon of pyranose and furanose residues. Carbon 245-251 complement C2 Homo sapiens 208-211 16358040-0 2005 An experimental study of melting of CCl4 in carbon nanotubes. Carbon 44-50 C-C motif chemokine ligand 4 Homo sapiens 36-40 16358040-3 2005 These results contrast with what was obtained in our previous measurements using carbon nanotubes with a pore diameter of 5.0 nm, where multiple transition temperatures both above and below the bulk melting point of CCl4 were observed. Carbon 81-87 C-C motif chemokine ligand 4 Homo sapiens 216-220 16006130-5 2005 The sulfanilamides acylated at the 4-amino group with short aliphatic/aromatic moieties incorporating 2-6 carbon atoms showed modest hCA XIV inhibitory activity (K(I)-s in the range of 1.25-4.2 microM) which were anyhow better than that of sulfanilamide (K(I) of 5.4 microM). Carbon 106-112 carbonic anhydrase 14 Homo sapiens 133-140 16268654-4 2005 A mechanism involving transmetalation, insertion of the carbon-carbon double bond into the C-Pd bond, and protonolysis of the resulting C-Pd bond is proposed. Carbon 56-62 carboxypeptidase D Homo sapiens 91-95 16268654-4 2005 A mechanism involving transmetalation, insertion of the carbon-carbon double bond into the C-Pd bond, and protonolysis of the resulting C-Pd bond is proposed. Carbon 56-62 carboxypeptidase D Homo sapiens 136-140 16268654-4 2005 A mechanism involving transmetalation, insertion of the carbon-carbon double bond into the C-Pd bond, and protonolysis of the resulting C-Pd bond is proposed. Carbon 63-69 carboxypeptidase D Homo sapiens 91-95 16268654-4 2005 A mechanism involving transmetalation, insertion of the carbon-carbon double bond into the C-Pd bond, and protonolysis of the resulting C-Pd bond is proposed. Carbon 63-69 carboxypeptidase D Homo sapiens 136-140 16292933-0 2005 Calculation of the circular dichroism spectra of carbon monoxy- and deoxy myoglobin: interpretation of a time-resolved circular dichroism experiment. Carbon 49-55 myoglobin Homo sapiens 74-83 16292933-1 2005 A calculation of the circular dichroism (CD) spectra of carbon monoxy- and deoxy myoglobin is carried out in relation with a time-resolved CD experiment. Carbon 56-62 myoglobin Homo sapiens 81-90 16234933-2 2005 Copper(I) complexes (Phe) and (PhePh) exhibited a distorted trigonal pyramidal structure involving a d-pi interaction with an eta1-binding mode between the metal ion and one of the ortho-carbon atoms of the phenyl group of the N-alkyl substituent [-CH2CH2Ph (Phe) and -CH2CHPh2(PhePh)]. Carbon 187-193 secreted phosphoprotein 1 Homo sapiens 126-130 16263928-1 2005 Thioredoxin f (TRXf) is a key factor in the redox regulation of chloroplastic carbon fixation enzymes, whereas glutathione is an important thiol buffer whose status is modulated by stress conditions. Carbon 78-84 thioredoxin Homo sapiens 0-11 16358787-5 2005 As a result, atoms C-3 and C-4 of glucose become enriched with the heavy isotope, and subsequent mixing of atoms and the specificity of interactions in the photorespiration chain lead to an isotope weighting of the other atoms and an uneven distribution of carbon isotopes in glucose-6-phosphate and other photorespiration products. Carbon 257-263 complement C4A (Rodgers blood group) Homo sapiens 27-30 16099857-7 2005 This possibility was also supported by the finding that the inhibitory effect of c-lact on NE-induced aa-nat induction was markedly reduced by cycloheximide, a protein synthesis inhibitor. Carbon 75-76 aralkylamine N-acetyltransferase Rattus norvegicus 102-108 16447436-2 2005 Activated carbon was oxidized in HNO3 aqueous solution at first (AC1), then treated in the mixture of NaOH and NaCl solution (AC2). Carbon 10-16 long intergenic non-protein coding RNA 1587 Homo sapiens 65-68 10856212-1 2000 Plant production in the sea is a primary mechanism of global oxygen formation and carbon fixation. Carbon 82-88 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 24-27 10808434-4 2000 The present route to the syntheses of various aminosugars with gluco- configurations from 5 alpha and 5 beta constitutes a novel method for the introduction of N-monoalkylated and N,N-dialkylated amines to the C-2 carbon of pyranoses in equatorial configurations. Carbon 214-220 complement C2 Homo sapiens 210-213 10832884-1 2000 Capillary zone electrophoresis was employed for the determination of myoglobin in human urine using end-column amperometric detection with a carbon fiber microelectrode at a constant potential of 1.80 V vs. saturated calomel electrode (SCF). Carbon 141-147 myoglobin Homo sapiens 69-78 10783074-5 2000 The rotation barrier of the C=C bond in TCNE2- is estimated by Hartree-Fock (HF), second-order Moller-Plesset perturbation (MP2) and fourth-order MP (MP4) calculations with 6-31G(d), 6-31+G(d) and 6-311+G(d) basis sets as 42-51 kJ mol(-1). Carbon 28-29 tryptase pseudogene 1 Homo sapiens 124-127 10803734-6 2000 Rp-8-CPT-cAMPS (a PKA inhibitor), U-73122 (a phospholipase C inhibitor), or calphostin C (a PKC inhibitor), blocked the dopamine-mediated biphasic effects on Na+-K+-ATPase activity. Carbon 5-6 protein kinase cAMP-activated catalytic subunit alpha Rattus norvegicus 18-21 10671842-1 2000 We evaluated a single-use, disposable, carbon-dioxide-powered, needleless injector (J-Tip, National Medical Products Inc., CA, USA), which is claimed to deliver a virtually painless, subcutaneous injection. Carbon 39-45 TOR signaling pathway regulator Homo sapiens 86-89 10955833-1 2000 Pseudomonas species strain PXM, which is able to use dicamba (3,6-dichloro-2-methoxybenzoic acid; CAS 1918-00-9, Banvel) as its sole carbon source for growth, has been isolated. Carbon 133-139 BCAR1 scaffold protein, Cas family member Homo sapiens 98-101 10639284-2 1999 The data reveal a remarkable potency enhancement in those compounds that contain an sp(2) center at the C-4 carbon of the ring relative to similar, saturated compounds. Carbon 108-114 complement C4A (Rodgers blood group) Homo sapiens 104-107 10639284-4 1999 Comparisons were then made against compounds with similar functionality where the C-4 carbon was reduced to sp(3) hybridization and the effect was typically an order of magnitude loss in potency. Carbon 86-92 complement C4A (Rodgers blood group) Homo sapiens 82-85 10836051-2 1999 The oxygen-carbon bond at C-1 was incorporated with complete stereoselectivity by using an efficient phenylselenocyclocarbamation reaction. Carbon 11-17 heterogeneous nuclear ribonucleoprotein C Homo sapiens 26-29 10604478-7 1999 TOR inhibits expression of carbon-source-regulated genes by stimulating the binding of the transcriptional activators MSN2 and MSN4 to the cytoplasmic 14-3-3 protein BMH2. Carbon 27-33 stress-responsive transcriptional activator MSN2 Saccharomyces cerevisiae S288C 118-122 10604478-7 1999 TOR inhibits expression of carbon-source-regulated genes by stimulating the binding of the transcriptional activators MSN2 and MSN4 to the cytoplasmic 14-3-3 protein BMH2. Carbon 27-33 14-3-3 family protein BMH2 Saccharomyces cerevisiae S288C 166-170 10570266-6 1999 The ability of overexpressed c-Cbl to inhibit signaling requires both Syk tyrosine 317 and a functional c-Cbl PTB domain. Carbon 29-31 spleen associated tyrosine kinase Gallus gallus 70-73 10628872-2 1999 Cat8p-dependent expression is mediated by cis-acting elements in the respective promoters, which are named UAS/CSREs (upstream activating sequence/carbon source responsive element). Carbon 147-153 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 0-5 10565290-0 1999 Myoglobin-containing carbon-paste enzyme microelectrodes for the biosensing of glucose under oxygen-deficit conditions. Carbon 21-27 myoglobin Homo sapiens 0-9 10565290-2 1999 The incorporation of the natural oxygen binder myoglobin into a GOx-containing carbon-paste matrix is shown to satisfy the oxygen demand of the enzymatic reaction and to provide convenient biosensing of glucose in oxygen-free solutions. Carbon 79-85 myoglobin Homo sapiens 47-56 10565290-6 1999 The myoglobin-doped mineral oil or Kel-F-based carbon-paste enzyme microelectrodes display a highly stable glucose response over prolonged (6-7 h) operations in oxygen-free solutions, indicating no depletion of the internal oxygen supply. Carbon 47-53 myoglobin Homo sapiens 4-13 10635554-5 1999 The UAS2 is the element involved in transcriptional regulation by carbon source and the target site for the factor, HAP2/3/4/5 protein complex, in Saccharomyces cerevisiae. Carbon 66-72 transcription activator HAP2 Saccharomyces cerevisiae S288C 116-126 10572946-7 1999 An upper limit of about 4 A for the distance between the C-2 carbons is deduced from the RFDR experiments. Carbon 61-68 complement C2 Homo sapiens 57-60 10540293-8 1999 Our data show that carbon source-dependent transcriptional activation by Cat8p is the most important mechanism affecting the regulated expression of gluconeogenic structural genes. Carbon 19-25 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 73-78 10504238-2 1999 Enzyme-bound cob(II)alamin was cryotrapped after formation by substrate-initiated, thermally activated cleavage of the cobalt-carbon bond of adenosylcobalamin. Carbon 126-132 metabolism of cobalamin associated B Homo sapiens 13-16 10504238-11 1999 A 14% increase in the isotropic hyperfine coupling of the remote dimethylbenzimidazole (14)N nucleus in enzyme-bound versus free base-on cob(II)alamin shows an enhanced delocalization of unpaired spin density from Co(II) onto the axial ligand, which would contribute to the acceleration of the cobalt-carbon bond cleavage rate in situ. Carbon 301-307 metabolism of cobalamin associated B Homo sapiens 137-140 10512631-1 1999 The effect of anion binding on iodopsin, the chicken red-sensitive cone visual pigment, was studied by measurements of the Fourier transform infrared spectra of chloride- and nitrate-bound forms of iodopsin at 77 K. In addition to the blue shift of the absorption maximum upon substituting nitrate for chloride, the C=C stretching vibrations of iodopsin and its photoproducts were upshifted 5-6 cm(-)(1). Carbon 316-317 opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan) Gallus gallus 31-39 10512631-1 1999 The effect of anion binding on iodopsin, the chicken red-sensitive cone visual pigment, was studied by measurements of the Fourier transform infrared spectra of chloride- and nitrate-bound forms of iodopsin at 77 K. In addition to the blue shift of the absorption maximum upon substituting nitrate for chloride, the C=C stretching vibrations of iodopsin and its photoproducts were upshifted 5-6 cm(-)(1). Carbon 318-319 opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan) Gallus gallus 31-39 10411744-3 1999 Among 52 proteins induced by a shift from 25 degrees C to 38 degrees C, half of them were found to be dependent upon Msn2p and/or Msn4p (including mostly antioxidants and enzymes involved in carbon metabolism), while the other half (including mostly chaperones and associated proteins) were dependent upon Hsf1p. Carbon 191-197 stress-responsive transcriptional activator MSN2 Saccharomyces cerevisiae S288C 117-122 10393280-3 1999 Membrane fractions, when isolated from this tester strain, contained 0.04 P450 nmol/mg protein and a reductase activity of 170 nmol cytochrome c reduced/min/mg protein and were active in catalyzing CYP1A2-dependent 7-ethoxyresorufin O-deethylation and metabolic activation of heterocyclic aromatic amines to DNA-damaging products in a conventional tester S. typhimurium NM2009 strain, only when NADPH was added as a reducing equivalent. Carbon 12-13 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 198-204 10403374-2 1999 cre1 encodes a 429 amino acid protein 59% similar to the carbon catabolite repressor CREA from Aspergillus nidulans. Carbon 57-63 Spt10p Saccharomyces cerevisiae S288C 0-4 10197966-1 1999 In this paper we report molecular dynamics (MD) and free energy perturbation (FEP) studies carried out on enzyme-inhibitor (two hydroxamates that only differ by a carbon-carbon double bond) complexes of human fibroblast collagenase to obtain insights into the structural and energetic preferences of these inhibitors. Carbon 163-169 matrix metallopeptidase 1 Homo sapiens 209-231 10197966-1 1999 In this paper we report molecular dynamics (MD) and free energy perturbation (FEP) studies carried out on enzyme-inhibitor (two hydroxamates that only differ by a carbon-carbon double bond) complexes of human fibroblast collagenase to obtain insights into the structural and energetic preferences of these inhibitors. Carbon 170-176 matrix metallopeptidase 1 Homo sapiens 209-231 9920883-1 1999 Growth of Saccharomyces cerevisiae with a fatty acid as carbon source was shown previously to require function of either glucose-6-phosphate dehydrogenase (ZWF1) or cytosolic NADP+-specific isocitrate dehydrogenase (IDP2), suggesting dependence of beta-oxidation on a cytosolic source of NADPH. Carbon 56-62 glucose-6-phosphate dehydrogenase Saccharomyces cerevisiae S288C 121-154 9920883-1 1999 Growth of Saccharomyces cerevisiae with a fatty acid as carbon source was shown previously to require function of either glucose-6-phosphate dehydrogenase (ZWF1) or cytosolic NADP+-specific isocitrate dehydrogenase (IDP2), suggesting dependence of beta-oxidation on a cytosolic source of NADPH. Carbon 56-62 glucose-6-phosphate dehydrogenase Saccharomyces cerevisiae S288C 156-160 10192997-3 1999 Familial hypercholesterolemia (FH) is a genetic disorder characterized by an elevation of LDL cholesterol (LDL-C) caused by molecular defects in the LDL receptor gene. Carbon 111-112 low density lipoprotein receptor Homo sapiens 149-161 10470377-0 1999 Folylpoly-gamma-glutamate synthetase: generation of isozymes and the role in one carbon metabolism and antifolate cytotoxicity. Carbon 81-87 folylpolyglutamate synthase Homo sapiens 0-36 10470377-12 1999 Cells expressing FPGS activity solely in the mitochondria are glycine prototrophs, but also possess cytosolic folylpolyglutamates and are prototrophic for thymidine and purines, products of cytosolic one carbon metabolism. Carbon 204-210 folylpolyglutamate synthase Homo sapiens 17-21 10036774-1 1998 Six-Carbon (C6-) volatiles, including the aldehydes trans-2-hexenal, hexanal and cis-3-hexenal, as well as their corresponding alcohols, are produced from damaged or wounded plant tissue as a product of the enzymatic activity of hydroperoxide lyase (HPL), a component of the lipoxygenase (LOX) pathway. Carbon 4-10 lipoxygenase 1 Arabidopsis thaliana 275-287 10036774-1 1998 Six-Carbon (C6-) volatiles, including the aldehydes trans-2-hexenal, hexanal and cis-3-hexenal, as well as their corresponding alcohols, are produced from damaged or wounded plant tissue as a product of the enzymatic activity of hydroperoxide lyase (HPL), a component of the lipoxygenase (LOX) pathway. Carbon 4-10 lipoxygenase 1 Arabidopsis thaliana 289-292 29711060-1 1998 MP2 calculations show that the D h isoelectronic dicarbonyl complexes [M(CO)2 ]n (Mn =Rh- , Pd0 , Cu+ , Ag+ , Au+ , Zn2+ , Cd2+ , Hg2+ ) depicted in structure 1 can be classified as classical or nonclassical depending on whether the metal-carbon bond lengths decrease or increase when weak, anionic ligands approach the metal centers. Carbon 51-57 tryptase pseudogene 1 Homo sapiens 0-3 9784860-1 1998 The substitution of the sterically hindered carbon of the potent thyroid hormone agonist, GC-1, was effected by a reaction based on the solvolysis of the benzylic hydroxyl group. Carbon 44-50 solute carrier family 25 member 22 Homo sapiens 90-94 9658690-5 1998 In order to collect information clinical trials have been performed on the reconstruction of root canal treated teeth using carbon fibe posts (COMPOSIPOST, RTD, France; C-POST, Bisco, USA). Carbon 124-130 solute carrier family 35 member G1 Homo sapiens 150-154 9603875-10 1998 Both in shake flask cultures and in carbon-limited chemostat cultures, MAE1 was constitutively expressed. Carbon 36-42 malate dehydrogenase (oxaloacetate-decarboxylating) Saccharomyces cerevisiae S288C 71-75 21781864-4 1998 While human CYP1A1, rat CYP1A1 and rat CYP1A2 formed almost exclusively the (-)-B[c]Ph-3R,4R-dihydrodiol, human CYP1A2 produced both the (-)-3R,4R- and the (+)-3S,4S-dihydrodiol enantiomers in a ratio of 2:1. Carbon 62-63 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 12-18 21781864-4 1998 While human CYP1A1, rat CYP1A1 and rat CYP1A2 formed almost exclusively the (-)-B[c]Ph-3R,4R-dihydrodiol, human CYP1A2 produced both the (-)-3R,4R- and the (+)-3S,4S-dihydrodiol enantiomers in a ratio of 2:1. Carbon 62-63 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 24-30 16137637-1 2005 Serine hydroxymethyltransferase (SHMT) is a key enzyme in the formation and regulation of the folate one-carbon pool. Carbon 105-111 serine hydroxymethyltransferase 1 Homo sapiens 0-31 16122687-5 2005 In addition, the effect of temperature on this association was investigated using an electrically heated DNA-modified carbon paste electrode (DNA/CPE). Carbon 118-124 carboxypeptidase E Homo sapiens 146-149 16030250-2 2005 The Saccharomyces cerevisiae GPCR Gpr1 and associated Galpha subunit Gpa2 sense extracellular carbon sources (including glucose) to govern filamentous growth. Carbon 94-100 Gpr1p Saccharomyces cerevisiae S288C 34-38 32273832-7 2020 After exposure to 0.05 to 1 Gy of carbon ions and 0.5 to 4 Gy of X-rays, only IGFBP-3 showed obvious increase with increased doses, both carbon ions and X-rays. Carbon 137-143 insulin like growth factor binding protein 3 Homo sapiens 78-85 9545524-13 1998 The dione compound 4-cyclopentene-1,3-dione, which has two potentially reactive carbons rather than one, was considerably more potent than 2-cyclopentene-1-one in repressing IGF-I gene expression (IC50 = 30 microM for 4-cyclopentene-1,3-dione as compared with 167 microM for 2-cyclopentene-1-one). Carbon 80-87 insulin-like growth factor 1 Rattus norvegicus 174-179 32273832-9 2020 The results showed the expression difference of IGFBP-3 presented from 6 to 24 hours post-irradiation by carbon ions and X-rays. Carbon 105-111 insulin like growth factor binding protein 3 Homo sapiens 48-55 31743647-3 2020 Here, we exploit genetically encoded phenyl azide photochemistry to define the direct covalent attachment of four different proteins, including the fluorescent protein GFP and a beta-lactamase binding protein (BBP), to carbon nanotube side walls. Carbon 219-225 TM2 domain containing 1 Homo sapiens 210-213 16183870-11 2005 In addition, the CD200+ CK7+ percentage was significantly lower in trophoblast cells incubated with poly (I:C) at a certain concentration, in vitro, while histocytochemical examination showed the CD200+ cells mainly scattered in placental tissue adjacent to the interface of the placenta and uterus. Carbon 17-18 CD200 antigen Mus musculus 196-201 16202243-8 2005 Fermentable carbon sources, such as glucose (at low concentrations), lactose and sucrose, as a sole carbon source, enhanced the synthesis of beta-galactosidase from the GGTII-lacZ fusion gene in wildtype KP1 cells but not in Pap1-negative cells. Carbon 12-18 regenerating family member 3 alpha Homo sapiens 225-229 9393711-1 1997 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to glycine with the transfer of the one-carbon group to tetrahydrofolate to form 5,10-methylenetetrahydrofolate. Carbon 123-129 SULB_RS08175 Saccharolobus solfataricus 0-31 32577617-4 2020 The rGO modified carbon paste electrode (rGO/CPE) was used as a highly sensitive electrochemical sensor for the detection of SY. Carbon 17-23 carboxypeptidase E Homo sapiens 45-48 9393711-1 1997 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible cleavage of serine to glycine with the transfer of the one-carbon group to tetrahydrofolate to form 5,10-methylenetetrahydrofolate. Carbon 123-129 SULB_RS08175 Saccharolobus solfataricus 33-37 16136229-5 2005 The beta-1,3-glucans can also interact with various one-dimensional architectures, such as single-walled carbon nanotubes, to produce unique nanocomposites, in which the single-walled carbon nanotubes are entrapped within the helical superstructure of beta-1,3-glucans. Carbon 105-111 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 4-12 16136229-5 2005 The beta-1,3-glucans can also interact with various one-dimensional architectures, such as single-walled carbon nanotubes, to produce unique nanocomposites, in which the single-walled carbon nanotubes are entrapped within the helical superstructure of beta-1,3-glucans. Carbon 184-190 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 4-12 31948754-3 2020 Nogo-66, a C-terminal domain of Nogo-A, binds to the Nogo-A receptor 1 (NgR1) and induces the collapse of growth cones and inhibits neurite outgrowth. Carbon 11-12 reticulon 4 Homo sapiens 32-38 16089455-5 2005 The outside attachment of two hydrogen atoms to two adjacent carbon atoms located between two six-membered rings of the C60 cage affects the orientation of the LiF molecule inside and increases the stability of LiF inside the cage by 45%. Carbon 61-67 LIF interleukin 6 family cytokine Homo sapiens 160-163 16089455-5 2005 The outside attachment of two hydrogen atoms to two adjacent carbon atoms located between two six-membered rings of the C60 cage affects the orientation of the LiF molecule inside and increases the stability of LiF inside the cage by 45%. Carbon 61-67 LIF interleukin 6 family cytokine Homo sapiens 211-214 16089455-6 2005 In contrast, when 60 hydrogen atoms were attached to the outside surface of the C60 cage, thus transforming all C=C double bonds into single bonds, the stability of the LiF inside was reduced by 34%. Carbon 80-81 LIF interleukin 6 family cytokine Homo sapiens 169-172 16089455-6 2005 In contrast, when 60 hydrogen atoms were attached to the outside surface of the C60 cage, thus transforming all C=C double bonds into single bonds, the stability of the LiF inside was reduced by 34%. Carbon 112-113 LIF interleukin 6 family cytokine Homo sapiens 169-172 16089455-7 2005 If two adjacent carbon atoms were removed from C60, the stability of LiF inside this defect C60 was reduced by 41%. Carbon 16-22 LIF interleukin 6 family cytokine Homo sapiens 69-72 9375354-1 1997 Sorption partition coefficients between water and organic carbon (Koc) for deuterated benzene, toluene, and ethylbenzene have been estimated by measuring values of the octanol-water partition coefficient (Kow) and HPLC retention factors (k1), which correlate closely to values of Koc. Carbon 58-64 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 66-69 9349284-1 1997 When cucumber roots are excised and incubated without a carbon source, isocitrate lyase (ICL) and malate synthase (MS) mRNAs increase significantly in amount. Carbon 56-62 isocitrate lyase Cucumis sativus 71-87 9349284-1 1997 When cucumber roots are excised and incubated without a carbon source, isocitrate lyase (ICL) and malate synthase (MS) mRNAs increase significantly in amount. Carbon 56-62 isocitrate lyase Cucumis sativus 89-92 31948754-3 2020 Nogo-66, a C-terminal domain of Nogo-A, binds to the Nogo-A receptor 1 (NgR1) and induces the collapse of growth cones and inhibits neurite outgrowth. Carbon 11-12 reticulon 4 Homo sapiens 53-59 32069406-1 2020 Developing electrocatalysts that are stable and efficient for CO2 reduction is important for constructing a carbon-neutral energy cycle. Carbon 108-114 complement C2 Homo sapiens 62-65 9505234-7 1997 Our results suggest that the configuration at carbon 4 might be more important than that of the hydroxyl group at carbon 5 for the development of the activity as a cofactor for dopamine beta-hydroxylase reaction. Carbon 46-52 dopamine beta-hydroxylase Homo sapiens 177-202 9505234-7 1997 Our results suggest that the configuration at carbon 4 might be more important than that of the hydroxyl group at carbon 5 for the development of the activity as a cofactor for dopamine beta-hydroxylase reaction. Carbon 114-120 dopamine beta-hydroxylase Homo sapiens 177-202 9260099-4 1997 Pyrolytic carbon-coated PET (PC) did not induce platelet adhesion after 15 min of contact, but a significant increase in CD62 was detected. Carbon 10-16 selectin P Homo sapiens 121-125 16042479-1 2005 The direct electrochemistry of myoglobin (Mb) has been observed at a glassy carbon (GC) electrode coated with silica sol-gel-encapsulated Mb film. Carbon 76-82 myoglobin Homo sapiens 31-40 16013885-5 2005 The mean centered data consistently showed the best correlations between the scores on PC1 and the number of carbon atoms in the adsorbate. Carbon 109-115 polycystin 1, transient receptor potential channel interacting Homo sapiens 87-90 32143495-0 2020 Kinetics of Prostate-Specific Antigen after Carbon Ion Radiotherapy for Prostate Cancer. Carbon 44-50 kallikrein related peptidase 3 Homo sapiens 12-37 9261186-9 1997 These data suggest that this lipoxygenase may play an important role during the germination process of cucumber and other plants and support our previous hypothesis that the specific oxygenation of the storage lipids may initiate their mobilization as a carbon and energy source for the growing seedling. Carbon 254-260 LOW QUALITY PROTEIN: linoleate 9S-lipoxygenase 6 Cucumis sativus 29-41 16013885-8 2005 A PCA analysis of all of the positive ion spectra revealed a good correlation between the number of carbon atoms in all of the adsorbates and the scores on PC1. Carbon 100-106 polycystin 1, transient receptor potential channel interacting Homo sapiens 156-159 32143495-1 2020 This study aimed to first elucidate prostate-specific antigen (PSA) kinetics in prostate cancer patients treated with carbon ion radiotherapy (CIRT). Carbon 118-124 kallikrein related peptidase 3 Homo sapiens 36-67 15925603-2 2005 The maximum gold adsorption capacity of wood shaving fly ash washed with tap water (WSFW) at 20, 30, 40, and 60 degrees C was 8.68, 7.79, 7.44, and 7.25 mg(Au)/g(adsorbent), respectively, while of activated carbon it was 76.78, 60.95, 56.13, and 51.90 mg(Au)/g(adsorbent), respectively. Carbon 207-213 target of Poxn Drosophila melanogaster 73-76 9244397-7 1997 Thus, although the myoglobin-promoted hydroxylation of linoleic acid into 11-hydroxylinoleic acid lacked apparent stereospecificity and produced equal amounts of the R and S enantiomers, the course of the reaction was stereospecific and involved hydrogen abstraction and oxygen insertion occurring with retention of absolute configuration of the carbon atom hydroxylated. Carbon 346-352 myoglobin Homo sapiens 19-28 31863720-2 2020 Herein, for the first time, boron (B)-modulated electrocatalytic characteristics in CoP anchored on the carbon nanotubes (B-CoP/CNT) with impressive HER activities over a wide pH range are reported. Carbon 104-110 caspase recruitment domain family member 16 Homo sapiens 84-87 15975858-0 2005 Carbon source dependent phosphorylation of the Gpr1 protein in the yeast Yarrowia lipolytica. Carbon 0-6 Gpr1p Saccharomyces cerevisiae S288C 47-51 9154823-3 1997 Strains in which RTS1 has been disrupted are temperature sensitive (ts) for growth, are hypersensitive to ethanol, are unable to grow with glycerol as their only carbon source, and accumulate at nonpermissive temperatures predominantly as large-budded cells with a 2N DNA content and a nondivided nucleus. Carbon 162-168 protein phosphatase 2A regulatory subunit RTS1 Saccharomyces cerevisiae S288C 17-21 15975858-3 2005 Here we show that Gpr1p is subjected to phosphorylation in dependence on the carbon source. Carbon 77-83 Gpr1p Saccharomyces cerevisiae S288C 18-23 31863720-2 2020 Herein, for the first time, boron (B)-modulated electrocatalytic characteristics in CoP anchored on the carbon nanotubes (B-CoP/CNT) with impressive HER activities over a wide pH range are reported. Carbon 104-110 caspase recruitment domain family member 16 Homo sapiens 124-127 15975858-4 2005 Exhaustion of the carbon source resulted in a complete dephosphorylation of Gpr1p, whereas addition of a new carbon source caused the phosphorylation of Gpr1p. Carbon 18-24 Gpr1p Saccharomyces cerevisiae S288C 76-81 31965271-5 2020 This study is the first to divide patients into three patterns, namely, A, B, and C, according to the M-protein reduction rate during the first two therapy cycles. Carbon 82-83 myomesin 2 Homo sapiens 102-111 15975858-4 2005 Exhaustion of the carbon source resulted in a complete dephosphorylation of Gpr1p, whereas addition of a new carbon source caused the phosphorylation of Gpr1p. Carbon 109-115 Gpr1p Saccharomyces cerevisiae S288C 153-158 15975858-5 2005 Almost all Gpr1p molecules became phosphorylated after addition of acetate, while other carbon sources only triggered the phosphorylation of about half of the Gpr1p molecules. Carbon 88-94 Gpr1p Saccharomyces cerevisiae S288C 159-164 15995202-4 2005 A convenient plate assay for LasR function was devised, based on the observation that lasR mutants did not grow on adenosine as the sole carbon source because a key degradative enzyme, nucleoside hydrolase (Nuh), is positively controlled by LasR. Carbon 137-143 transcriptional regulator LasR Pseudomonas aeruginosa PAO1 29-33 9139747-8 1997 Raising the cellular concentration of fructose-2,6-bisphosphate, a potent effector of the direction of carbon flux through the gluconeogenic and glycolytic pathways, also stimulated glucose-6-phosphatase gene expression in Fao cells. Carbon 103-109 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 182-203 9111319-1 1997 The Cat8p zinc cluster protein is essential for growth of Saccharomyces cerevisiae with nonfermentable carbon sources. Carbon 103-109 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 4-9 31771419-1 2020 Phosphoenolpyruvate carboxylase (PEPC) is a carbon-fixing enzyme with critical roles in seed development. Carbon 44-50 phosphoenolpyruvate carboxylase, housekeeping isozyme Glycine max 0-31 9111319-8 1997 This activation capacity was still carbon source regulated and depended on the Cat1p (Snf1p) protein kinase, which indicated that Cat8p needs posttranslational modification to reveal its gene-activating function. Carbon 35-41 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 130-135 15882852-5 2005 Deprotonation-induced chemical shifts in pH-variable (13)C NMR spectra show that the OH-groups next to internal carbon atoms C-3 and C-4 dissociate to a greater extent compared to OH-groups next to external carbon atoms C-1 and C-6. Carbon 112-118 heterogeneous nuclear ribonucleoprotein C Homo sapiens 220-231 15882852-5 2005 Deprotonation-induced chemical shifts in pH-variable (13)C NMR spectra show that the OH-groups next to internal carbon atoms C-3 and C-4 dissociate to a greater extent compared to OH-groups next to external carbon atoms C-1 and C-6. Carbon 57-58 complement C4A (Rodgers blood group) Homo sapiens 133-136 15882852-5 2005 Deprotonation-induced chemical shifts in pH-variable (13)C NMR spectra show that the OH-groups next to internal carbon atoms C-3 and C-4 dissociate to a greater extent compared to OH-groups next to external carbon atoms C-1 and C-6. Carbon 57-58 heterogeneous nuclear ribonucleoprotein C Homo sapiens 220-231 31771419-1 2020 Phosphoenolpyruvate carboxylase (PEPC) is a carbon-fixing enzyme with critical roles in seed development. Carbon 44-50 phosphoenolpyruvate carboxylase, housekeeping isozyme Glycine max 33-37 15882852-5 2005 Deprotonation-induced chemical shifts in pH-variable (13)C NMR spectra show that the OH-groups next to internal carbon atoms C-3 and C-4 dissociate to a greater extent compared to OH-groups next to external carbon atoms C-1 and C-6. Carbon 207-213 complement C4A (Rodgers blood group) Homo sapiens 133-136 9103193-3 1997 Model results show that of the 40 teragrams of carbon produced annually in the Antarctic ice pack, 75 percent was associated with first-year ice and nearly 50 percent was produced in the Weddell Sea. Carbon 47-53 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 195-198 32108209-5 2020 We find that introduction of Br- species and their subsequent reactions with organic carbon are associated with an average of 39% loss of org-Cl species from leaf litter and soil. Carbon 85-91 chromosome 12 open reading frame 73 Homo sapiens 29-31 9054378-1 1997 Conversion of heme to verdoheme by heme oxygenase-1 (HO-1) is thought to involve alpha-meso-hydroxylation and elimination of the meso-carbon as CO, a reaction supported by both H2O2 and NADPH-cytochrome P450 reductase/O2. Carbon 134-140 heme oxygenase 1 Homo sapiens 35-51 31912675-0 2020 Significance of PD-L1 expression in carbon-ion radiotherapy for uterine cervical adeno/adenosquamous carcinoma. Carbon 36-42 CD274 molecule Homo sapiens 16-21 15770709-3 2005 The operative mechanism starts with the first exo-methylene C=C insertion into the Sm-H bond in a 1,2 fashion and is followed by shift-based beta-alkyl eliminative cyclopropyl ring opening by cleavage of a proximal bond, while the alternative mechanism that commences with 2,1-insertion and subsequent ring opening by distal bond scission is revealed to be almost entirely precluded. Carbon 60-61 coiled-coil domain containing 103 Homo sapiens 83-87 15770709-3 2005 The operative mechanism starts with the first exo-methylene C=C insertion into the Sm-H bond in a 1,2 fashion and is followed by shift-based beta-alkyl eliminative cyclopropyl ring opening by cleavage of a proximal bond, while the alternative mechanism that commences with 2,1-insertion and subsequent ring opening by distal bond scission is revealed to be almost entirely precluded. Carbon 62-63 coiled-coil domain containing 103 Homo sapiens 83-87 9012749-7 1997 Platinum/carbon replicas and thin sections of fracture-label specimens permitted high-resolution visualization of the distribution of dystrophin in plane views of the freeze-fractured plasma membrane and in relation to the sarcomeric banding patterns of the underlying myofibrils. Carbon 9-15 dystrophin Rattus norvegicus 134-144 31912675-2 2020 The aim of this study was to investigate the effects of carbon-ion (C-ion) beam irradiation on PD-L1 expression in human uterine cervical adeno/adenosquamous carcinoma (UCAA) cells and clinical samples and to identify the prognostic factors for outcomes after C-ion radiotherapy (CIRT). Carbon 56-62 CD274 molecule Homo sapiens 95-100 15852111-5 2005 In the presence of PPh3, complexes act as a Michael acceptor to afford the zwitterionic sigma-allenylphosphonium complexes (eta5-MeC5H4)(CO)2MnC(R)=C=C(PPh3)R" (5) resulting from nucleophilic attack by the phosphine on the remote alkynyl carbon atom. Carbon 238-244 protein phosphatase 4 catalytic subunit Homo sapiens 19-23 31912675-2 2020 The aim of this study was to investigate the effects of carbon-ion (C-ion) beam irradiation on PD-L1 expression in human uterine cervical adeno/adenosquamous carcinoma (UCAA) cells and clinical samples and to identify the prognostic factors for outcomes after C-ion radiotherapy (CIRT). Carbon 68-69 CD274 molecule Homo sapiens 95-100 15852111-5 2005 In the presence of PPh3, complexes act as a Michael acceptor to afford the zwitterionic sigma-allenylphosphonium complexes (eta5-MeC5H4)(CO)2MnC(R)=C=C(PPh3)R" (5) resulting from nucleophilic attack by the phosphine on the remote alkynyl carbon atom. Carbon 238-244 protein phosphatase 4 catalytic subunit Homo sapiens 152-156 15852111-6 2005 Complexes 5 exhibit a dynamic process in solution, which has been rationalized in terms of a fast [NMR time-scale] rotation of the allene substituents around the allene axis; metrical features within the X-ray structure of (eta5-MeC5H4)(CO)2MnC(Ph)=C=C(PPh3)Tol (5b) support the proposal. Carbon 0-1 protein phosphatase 4 catalytic subunit Homo sapiens 253-257 31912675-2 2020 The aim of this study was to investigate the effects of carbon-ion (C-ion) beam irradiation on PD-L1 expression in human uterine cervical adeno/adenosquamous carcinoma (UCAA) cells and clinical samples and to identify the prognostic factors for outcomes after C-ion radiotherapy (CIRT). Carbon 170-171 CD274 molecule Homo sapiens 95-100 15839688-3 2005 These results clearly indicate that the carbocations (10-C-5) bearing the sterically flexible benzene ligand were quite sensitive to the electronic effect on the central carbon atom. Carbon 170-176 complement C5 Homo sapiens 57-60 9043110-10 1997 Northern blot analyses showed that expression of the LIP1 transcript, the cloned gene which encodes a lipase, was detected only when C. albicans was grown in media containing Tween 80, other Tweens or triglycerides as the sole carbon source, and not in Sabouraud Dextrose Broth or yeast/peptone/dextrose media. Carbon 227-233 sphingosine N-acyltransferase subunit LIP1 Saccharomyces cerevisiae S288C 53-57 31912675-3 2020 METHODS: The effects of C-ion irradiation on PD-L1 expression in human UCAA and cervical squamous cell carcinoma cells were examined by flow cytometry. Carbon 24-25 CD274 molecule Homo sapiens 45-50 31912675-4 2020 We examined PD-L1 expression in UCAA biopsy specimens from 33 patients before CIRT started (pre-CIRT) and after 12 Gy (relative biological effectiveness [RBE]) irradiation (post-12Gy-C) in 4 fractions of CIRT to investigate the correlation between PD-L1 status and clinical outcomes. Carbon 33-34 CD274 molecule Homo sapiens 12-17 8999873-6 1997 The aldehyde moiety of the sugar phosphate is located in the vicinity of the C-2 carbon atom of the thiazolium ring of the cofactor. Carbon 81-87 complement C2 Homo sapiens 77-80 15917612-2 2005 In a previous presentation, we reported the screening and liquid fermentation with Aspergillus niger, strain C-6 for beta-glucosidase production at shake flask cultures in a basal culture medium with mineral salts, corn syrup liquor, and different waste lignocellulosic materials as the sole carbon source obtaining the maximum enzymatic activity after 5-6 d of 8.5 IU/mL using native sugar cane bagasse. Carbon 292-298 beta-glucosidase Zea mays 117-133 15917612-3 2005 In this work we describe the evaluation of fermentation conditions: growth temperature, medium composition, and pH, also the agitation and aeration effects for beta-glucosidase production under submerged culture using a culture media with corn syrup liquor (CSL) and native sugar cane bagasse pith as the sole carbon source in a laboratory fermenter. Carbon 310-316 beta-glucosidase Zea mays 160-176 31912675-5 2020 RESULTS: The PD-L1 expression was upregulated by C-ion beam in a dose-dependent manner in HeLa and SiHa cells through phosphorylated Chk1. Carbon 49-50 CD274 molecule Homo sapiens 13-18 15780659-2 2005 One such system, the target of rapamycin (Tor) proteins, senses nutrients and uses the GATA activators Gln3p and Nil1p to regulate translation in response to low-quality carbon and nitrogen. Carbon 170-176 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 103-108 31912675-7 2020 The post-12Gy-C PD-L1 expression was significantly elevated compared to the pre-CIRT PD-L1 expression. Carbon 14-15 CD274 molecule Homo sapiens 16-21 15780659-4 2005 When carbon and nitrogen are abundant, the phosphorylated Ure2p anchors the also phosphorylated Gln3p and Nil1p in the cytoplasm. Carbon 5-11 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 96-101 9042089-12 1997 NT and C, respectively (6.7 vs. 4.7 vs. 5.3 microU mL-1). Carbon 7-8 L1 cell adhesion molecule Mus musculus 51-55 31912675-9 2020 However, the post-12Gy-C PD-L1 expression had better correlation with PFS, but not with LC and OS. Carbon 23-24 CD274 molecule Homo sapiens 25-30 8970157-1 1996 We show that cells deleted for SNF3, HXT1, HXT2, HXT3, HXT4, HXT6, and HXT7 do not take up glucose and cannot grow on media containing glucose as a sole carbon source. Carbon 153-159 hexose transporter HXT3 Saccharomyces cerevisiae S288C 49-53 31658388-6 2020 The NMR solution structure of a fourth member of the DUF3349 superfamily, MAB_3403c, with 18 residues missing at the N-terminus, revealed a monomeric alpha-helical protein with a folding topology similar to the three C-terminal helices in the protomer of the MSMEG_1066 tetramer. Carbon 217-218 MAB_3403c Mycobacterium abscessus 74-83 8841414-9 1996 Expression of Pcs60p is highly inducible by oleic acid, however, the protein is dispensable for growth on oleic acid as single carbon source. Carbon 127-133 Pcs60p Saccharomyces cerevisiae S288C 14-20 15789595-1 2005 The use of rigid carbon fiber couch inserts in radiotherapy treatment couches is a well-established method of reducing patient set-up errors associated with couch sag. Carbon 17-23 S-antigen visual arrestin Homo sapiens 163-166 15707627-4 2005 For phenanthrene aqueous concentrations of 1 microg l(-1), the organic carbon-normalized sorption coefficients (log K(oc)) ranging from 5.0 to 6.4 for field chars and 5.4-7.3 for laboratory wood chars, which is consistent with literature values (5.6-7.1). Carbon 71-77 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 116-121 31771979-5 2020 Stable proteoforms resulted from cleavages near the start of the YRS C-terminal EMAPII domain: All of the MMPs tested cleaved at ADS386 387LYV and VSG405 406LVQ, generating 43-kDa and 45-kDa fragments. Carbon 69-70 matrix metallopeptidase 7 Homo sapiens 106-110 15456402-12 2005 The presence of a signal peptide indicates that SSO1949 is a secreted protein, which enables S. solfataricus to use cellulose as an external carbon source. Carbon 141-147 endoglucanase Saccharolobus solfataricus P2 48-55 8663394-5 1996 Disruption of the TOM71 gene does not reduce cell growth, except on nonfermentable carbon sources at elevated temperatures. Carbon 83-89 protein channel TOM71 Saccharomyces cerevisiae S288C 18-23 32075221-4 2020 However, the role and mechanisms of CEMP1"s C-terminal-derived synthetic peptide (CEMP1-p4) in the canonical Wnt/beta-catenin signaling pathway are yet to be described. Carbon 36-37 cementum protein 1 Homo sapiens 82-87 8643469-4 1996 These results suggest that the GDH1 gene product functions in the direction of glutamate catabolism under carbon-limiting conditions. Carbon 106-112 glutamate dehydrogenase 1 Arabidopsis thaliana 31-35 8643469-6 1996 Under such conditions of carbon and ammonia excess, GDH1 may function in the direction of glutamate biosynthesis. Carbon 25-31 glutamate dehydrogenase 1 Arabidopsis thaliana 52-56 8882811-3 1996 First by use of the back-propagation method the exo/endo branching of norbornane and norbornene derivatives was correctly predicted from the set of 13C NMR chemical shifts for various ring carbon atoms. Carbon 189-195 mannosidase endo-alpha Homo sapiens 52-56 15707062-2 2005 This research investigated the effect of the reaction energy on the reaction pathway for C-Cl bond cleavage in carbon tetrachloride (CCl4). Carbon 89-90 C-C motif chemokine ligand 4 Homo sapiens 133-137 15707062-4 2005 The potential energies associated with fragmentation of the carbon tetrachloride anion radical (CCl4-) into a trichloromethyl radical (CCl3) and a chloride ion (Cl-) were explored as a function of the carbon-chlorine bond distance during cleavage. Carbon 60-66 C-C motif chemokine ligand 4 Homo sapiens 96-100 15531579-10 2005 Furthermore, this study establishes that SHMT1 is a zinc-inducible gene, which provides the first mechanism for the regulation of folate-mediated one-carbon metabolism by zinc. Carbon 150-156 serine hydroxymethyltransferase 1 Homo sapiens 41-46 8882811-5 1996 It was shown in this case that the NMR shifts for two carbon atoms out of seven have strong correlation with the exo/endo branching. Carbon 54-60 mannosidase endo-alpha Homo sapiens 117-121 32075221-4 2020 However, the role and mechanisms of CEMP1"s C-terminal-derived synthetic peptide (CEMP1-p4) in the canonical Wnt/beta-catenin signaling pathway are yet to be described. Carbon 36-37 catenin beta 1 Homo sapiens 113-125 31769059-6 2020 The C-gate and the extreme C-terminal region are important for H2ApT120-dependent localization of TOP2A at centromeres. Carbon 4-5 DNA topoisomerase II alpha Homo sapiens 98-103 8555200-1 1996 The pH dependence of the 13C chemical shifts of the side-chain carboxyl carbons of all Asp and Glu residues in the reduced and oxidized states of human thioredoxin and in a mixed disulfide complex of human thioredoxin with a target peptide from the transcription factor NF kappa B has been investigated by multidimensional triple-resonance NMR spectroscopy. Carbon 72-79 thioredoxin Homo sapiens 152-163 15624931-5 2005 The effect on enantioselectivity of the carbon chain length of the R group located (1) on the C-3 substituent of 4a-d, 6a-d, and 7a-d or (2) at C-5 in 8a-d and 9a-g was studied in detail. Carbon 40-46 complement C5 Homo sapiens 144-147 8555200-1 1996 The pH dependence of the 13C chemical shifts of the side-chain carboxyl carbons of all Asp and Glu residues in the reduced and oxidized states of human thioredoxin and in a mixed disulfide complex of human thioredoxin with a target peptide from the transcription factor NF kappa B has been investigated by multidimensional triple-resonance NMR spectroscopy. Carbon 72-79 thioredoxin Homo sapiens 206-217 31769059-6 2020 The C-gate and the extreme C-terminal region are important for H2ApT120-dependent localization of TOP2A at centromeres. Carbon 27-28 DNA topoisomerase II alpha Homo sapiens 98-103 32093595-6 2020 Earlier, the molecular dynamics approach was used to study the conformational dynamics of such human OGG1 mutants in complexes with the oxoG:C-containing substrate DNA, and the population density of certain conformers of two OGG1 catalytic residues, Lys249 and Asp268, was suggested to determine the enzyme activity. Carbon 141-142 8-oxoguanine DNA glycosylase Homo sapiens 101-105 27299556-3 1996 The thermal isomerization of methyl epijamonate to methyl jasmonate was also clarified by optically resolved gas chromatography to have occurred at the asymmetric carbon of the C-2 position that is connected to the carbonyl group. Carbon 163-169 complement C2 Homo sapiens 177-180 16492548-7 2005 Thus, in the rat, endogenous amylin secreted in response to meals appeared to mobilize carbon from skeletal muscle. Carbon 87-93 islet amyloid polypeptide Rattus norvegicus 29-35 32093595-7 2020 Here, we report the study of molecular dynamics of human OGG1 bound to the oxoG:A-containing DNA and OGG1 mutants bound to the AP:C-containing DNA. Carbon 130-131 8-oxoguanine DNA glycosylase Homo sapiens 101-105 31923807-9 2020 Overall, the results show that the glycosylase domain of NEIL3, lacking the C-terminal NPL4 and GRF zinc finger motifs, is competent to unhook the dA-AP ICL in splayed substrates and independently enforces important substrate preferences on the repair process. Carbon 76-77 nei like 3 (E. coli) Mus musculus 57-62 16295885-8 2005 Due to solubility-enhancement of phenanthrene, the partition coefficients normalized by organic carbon contents decrease with increasing system temperature (i.e., ln Koc = -0.284 ln S + 9.82 (n = 4, r2 = 0.992)). Carbon 96-102 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 166-169 12089766-1 1996 This article represents a clinical report from daily experience with the C-POST system, a carbon-fiber post for core build-up. Carbon 90-96 solute carrier family 35 member G1 Homo sapiens 75-79 12089766-1 1996 This article represents a clinical report from daily experience with the C-POST system, a carbon-fiber post for core build-up. Carbon 90-96 solute carrier family 35 member G1 Homo sapiens 103-107 16399379-7 2005 DCA was found to be a mechanism-based inactivator of GSTZ, and proteomic studies showed that Cys-16 of human GSTZ1-1 is covalently modified by a reactive intermediate that contains glutathione and the carbon skeleton of DCA. Carbon 201-207 glutathione S-transferase zeta 1 Homo sapiens 109-116 9090846-0 1996 Oxygen- and carbon source-dependent transactivation effect of ABF1 on the expression of the AAC2 gene encoding mitochondrial ADP/ATP carrier. Carbon 12-18 musculin Homo sapiens 62-66 31821485-3 2020 The current study investigates the importance of the two isoenzymes of pyruvate carboxylase (PYC1 and PYC2) and one of the key enzymes of the glyoxylate cycle (ICL1) for growth on glycerol (C3) as a sole carbon source. Carbon 204-210 pyruvate carboxylase 1 Saccharomyces cerevisiae S288C 93-97 31846774-6 2020 Moreover, the expression levels of OnIRAK1 and OnIRAK4 were clearly altered in all five tissues after Streptococcus agalactiae infection in vivo and could be induced by LPS, Poly I: C, S. agalactiae WC1535 and CPS in Nile tilapia macrophages. Carbon 182-183 interleukin-1 receptor-associated kinase 4 Oreochromis niloticus 47-54 31645646-3 2020 RET is expressed as two main isoforms with unique C-terminal sequences that differ in protein interactions and subcellular trafficking in response to RET activation, and which also have distinct oncogenic potentials. Carbon 50-51 ret proto-oncogene Homo sapiens 0-3 8528003-6 1995 Cdc28 and cdc35 mutants of Saccharomyces cerevisiae had been previously shown to exhibit high respiratory quotients (from 3 to 7) in respect to the WT (RQ approximately 1.0), which correlated with carbon and energy uncoupling probably the result of glucose-induced catabolite repression [Aon MA, Monaco ME, Cortassa S (1995) Exp Cell Res 217, 42-51; Monaco ME, Valdecantos PA, Aon MA (1995) Exp Cell Res 217, 52-56]. Carbon 197-203 cyclin-dependent serine/threonine-protein kinase CDC28 Saccharomyces cerevisiae S288C 0-5 8750239-4 1995 Disruption-deletion of the GDS1 open reading frame leads to a partial impairment of growth on medium containing glycerol as the carbon source, indicating mitochondrial function of the gene product. Carbon 128-134 Gds1p Saccharomyces cerevisiae S288C 27-31 15278309-2 2004 Two nahR knockout strains (RK1 and Cg1-NAHR from P. putida NCIB 9816-4 and Cg1, respectively) showed a growth defect in the presence of naphthalene as sole carbon and energy source. Carbon 156-162 NahR Pseudomonas putida 4-8 15278309-2 2004 Two nahR knockout strains (RK1 and Cg1-NAHR from P. putida NCIB 9816-4 and Cg1, respectively) showed a growth defect in the presence of naphthalene as sole carbon and energy source. Carbon 156-162 NahR Pseudomonas putida 39-43 31645646-7 2020 Our data show that the GRB2 adapter associates with RET51 through interactions with its C-terminal sequences, facilitating recruitment of active ARF6 and GGA3 interaction, and that depletion of GGA3 or ARF6 reduced RET51 recycling. Carbon 88-89 ret proto-oncogene Homo sapiens 52-57 7503767-7 1995 The IC50s calculated from their Ki values were in the order of F-2 < C-2 < FZ < CZ < C-4 << F-1, indicating that C-2 and F-2 exhibit higher affinities for D2-R than the parent drugs, whereas affinities of other metabolites were 1 to 2 orders of magnitude less than those of C-2 and F-2. Carbon 5-6 complement C2 Rattus norvegicus 72-75 7503767-7 1995 The IC50s calculated from their Ki values were in the order of F-2 < C-2 < FZ < CZ < C-4 << F-1, indicating that C-2 and F-2 exhibit higher affinities for D2-R than the parent drugs, whereas affinities of other metabolites were 1 to 2 orders of magnitude less than those of C-2 and F-2. Carbon 5-6 complement C2 Rattus norvegicus 131-134 31645646-7 2020 Our data show that the GRB2 adapter associates with RET51 through interactions with its C-terminal sequences, facilitating recruitment of active ARF6 and GGA3 interaction, and that depletion of GGA3 or ARF6 reduced RET51 recycling. Carbon 88-89 ADP ribosylation factor 6 Homo sapiens 145-149 7503767-7 1995 The IC50s calculated from their Ki values were in the order of F-2 < C-2 < FZ < CZ < C-4 << F-1, indicating that C-2 and F-2 exhibit higher affinities for D2-R than the parent drugs, whereas affinities of other metabolites were 1 to 2 orders of magnitude less than those of C-2 and F-2. Carbon 5-6 complement C2 Rattus norvegicus 131-134 15549797-4 2004 Allenes with electron-donating alkyl substituents R sterically unencumbered at the C-3 and C-4 carbons reacted with palladacycles I to afford benzopyrans IV in good yields (45-81%), exclusively as cis diastereomers. Carbon 95-102 complement C4A (Rodgers blood group) Homo sapiens 91-94 31645646-7 2020 Our data show that the GRB2 adapter associates with RET51 through interactions with its C-terminal sequences, facilitating recruitment of active ARF6 and GGA3 interaction, and that depletion of GGA3 or ARF6 reduced RET51 recycling. Carbon 88-89 ADP ribosylation factor 6 Homo sapiens 202-206 32024184-4 2020 Adsorption experiments showed that the adsorption capacities of CCSP were more than 605 and 539 mg/g for Reactive Black 5 and Reactive Orange 131, respectively, which were over 10 times larger than that of commercial activated carbon (AC). Carbon 227-233 secretoglobin family 1A member 1 Homo sapiens 64-68 15538798-4 2004 The major disadvantage to the use of fullerenes is the isobaric interference between matrix and analyte ions; however, it is overcome by using MALDI-ion mobility time-of-flight (IM-oTOF) mass spectrometry to preseparate carbon cluster ions from bioanalyte ions prior to TOF mass analysis. Carbon 220-226 otoferlin Rattus norvegicus 181-185 7588747-2 1995 Transcription of the QCR8 gene, encoding subunit VIII of the Saccharomyces cerevisiae mitochondrial ubiquinol-cytochrome c oxidoreductase (QCR), is controlled by the carbon-source-dependent heme-activator protein complex HAP2/3/4 and the general transcriptional regulators autonomous replication-site-binding factor ABF1 and centromere-binding and promoter-binding factor CPF1. Carbon 166-172 ubiquinol--cytochrome-c reductase subunit 8 Saccharomyces cerevisiae S288C 21-25 7588747-2 1995 Transcription of the QCR8 gene, encoding subunit VIII of the Saccharomyces cerevisiae mitochondrial ubiquinol-cytochrome c oxidoreductase (QCR), is controlled by the carbon-source-dependent heme-activator protein complex HAP2/3/4 and the general transcriptional regulators autonomous replication-site-binding factor ABF1 and centromere-binding and promoter-binding factor CPF1. Carbon 166-172 transcription activator HAP2 Saccharomyces cerevisiae S288C 221-229 31816713-0 2020 Highly sensitive voltammetric immunosensor for the detection of prostate specific antigen based on silver nanoprobe assisted graphene oxide modified screen printed carbon electrode. Carbon 164-170 kallikrein related peptidase 3 Homo sapiens 64-89 8586402-0 1995 [The adsorption mechanism of Pb2+, Cd2+, Ni2+ and Co2+ onto activated carbon particles]. Carbon 70-76 complement C2 Homo sapiens 50-53 8586402-1 1995 The adsorption of Pb2+, Cd2+, Ni2+, Co2+ on activated carbon particles was studied as a function of pH and concentrations of adsorbates. Carbon 54-60 complement C2 Homo sapiens 36-39 8586402-4 1995 Conditional adsorption constants of surface complexes of Pb2+, Cd2+, Ni2+ and Co2+ with activated carbon particles were calculated by a simplified surface complexation model. Carbon 98-104 complement C2 Homo sapiens 78-81 15453723-2 2004 Our new artificial acylase, tert-butyldiphenylsilyl ether of N-(2,4,6-triisopropylbenzenesulfonyl)-pi(Me)-l-histidinol, is a simple and small molecule (molecular weight = 660) that contains only one chiral carbon center that originates from natural l-histidine. Carbon 206-212 telomerase reverse transcriptase Homo sapiens 28-32 31816713-1 2020 In this work, we developed an effective voltammetric immunosensing platform for the sensitive detection of prostate specific antigen (PSA) utilizing a graphene oxide (GO) modified screen-printed carbon electrode (SPCE) hybridized with the ex-situ prepared silver nanoparticles (AgNPs) as a probe and signal transducer. Carbon 195-201 kallikrein related peptidase 3 Homo sapiens 107-132 7496532-2 1995 The role of the IMP2 gene product in the regulation of carbon catabolite repressible enzymes maltase, invertase, alcohol dehydrogenase, NAD-dependent glutamate dehydrogenase (NAD-GDH) and L-lactate:ferricytochrome-c oxidoreductase (L-LCR) was also analysed. Carbon 55-61 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 16-20 31816713-1 2020 In this work, we developed an effective voltammetric immunosensing platform for the sensitive detection of prostate specific antigen (PSA) utilizing a graphene oxide (GO) modified screen-printed carbon electrode (SPCE) hybridized with the ex-situ prepared silver nanoparticles (AgNPs) as a probe and signal transducer. Carbon 195-201 kallikrein related peptidase 3 Homo sapiens 134-137 7496532-3 1995 The IMP2 gene product is required for the rapid glucose derepression of all above-mentioned carbon source utilization pathways and of all the enzymes except for L-LCR. Carbon 92-98 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 4-8 31915781-5 2020 Computational results (MP2/aug-cc-pVDZ) reproduce this observation and allow one to conclude that the increase of 1JCH is mainly caused by the change of the carbon hybridization (an increase of s-character), rather than by the change in interatomic distance rCH. Carbon 157-163 tryptase pseudogene 1 Homo sapiens 23-26 21597803-1 1995 Operative specimens from 7 patients with urinary bladder cancer and with only inflammatory tissue in the operative sample from one patient, were used for frozen section autoradiography using [C-11]harmine to characterize the expression of the enzyme monoamine oxidase A (MAO-A). Carbon 192-193 monoamine oxidase A Homo sapiens 250-269 15309370-2 2004 It is based on the enhanced oxidation of lovastatin at a novel acetylene black-dihexadecyl hydrogen phosphate composite-modified glassy-carbon electrode (AB-DHP/GCE) in the presence of Triton X-100. Carbon 136-142 aminomethyltransferase Homo sapiens 161-164 15309370-3 2004 This electrode was prepared by dispersion of acetylene black particles in an aqueous suspension of DHP and the formation of a stable film of the resulting AB-DHP composite on the surface of a glassy carbon electrode (GCE). Carbon 199-205 aminomethyltransferase Homo sapiens 217-220 15289857-6 2004 We herein evaluate the cytotoxic effects of heavy carbon-ion beams combined with p53 gene transfer on human esophageal SCC. Carbon 50-56 serpin family B member 3 Homo sapiens 119-122 15289857-11 2004 These data suggest that heavy carbon-ion beam irradiation combined with Ad.p53 may be a potentially effective therapeutic strategy for locally advanced esophageal SCC. Carbon 30-36 serpin family B member 3 Homo sapiens 163-166 7476212-6 1995 Analysis of gene transcription by a CAT-reporter gene fused to the GPD promoters revealed decreased transcriptional activity of the GPD2 promoter in cells grown on nonfermentable as opposed to fermentable carbon sources, and no induction in cells exposed to high osmolarity or heat shock. Carbon 205-211 glycerol-3-phosphate dehydrogenase (NAD(+)) GPD2 Saccharomyces cerevisiae S288C 132-136 31964814-7 2020 Specifically, leaf damage inflicted by insect herbivory or mechanical wounding at ET resulted in COI1-dependent stomatal closure, leading to increased leaf temperature, lower photosynthetic carbon assimilation rate, and growth inhibition. Carbon 190-196 coronatine-insensitive 1 Solanum lycopersicum 97-101 15298386-1 2004 We describe here a new approach to the synthesis of size-controllable polypyrrole/carbon nanotube (CNT) nanocables by in situ chemical oxidative polymerization directed by the cationic surfactant cetyltrimethylammonium bromide (CTAB) or the nonionic surfactant polyethylene glycol mono-p-nonylphenyl ether (Opi-10). Carbon 82-88 heat shock protein nuclear import factor hikeshi Homo sapiens 307-313 15298386-2 2004 When carbon nanotubes are dispersed in a solution containing a certain concentration of CTAB or Opi-10, the surfactant molecules are adsorbed and arranged regularly on the CNT surfaces. Carbon 5-11 heat shock protein nuclear import factor hikeshi Homo sapiens 96-102 32038681-7 2019 Complementation analysis in yeast showed that CHA1 could successfully reach the PM, and that proton pump activity was obtained when the last 77 up to 87 amino acids of the C-terminal domain were deleted. Carbon 0-1 L-serine/L-threonine ammonia-lyase CHA1 Saccharomyces cerevisiae S288C 46-50 15123691-5 2004 Also, rho+ sue1 strains containing certain altered holo-iso-1-cytochromes c grew better on non-fermentable carbon sources than the corresponding rho+ SUE1 strains. Carbon 107-113 Sue1p Saccharomyces cerevisiae S288C 11-15 15252576-3 2004 It was found that the diyne ligand easily reacts with all these complexes to give [HOs(3)(CO)8(PR3)-[mu3, eta1:eta3:eta1)-(CH(3)-C-C=CH-CH=C-O)]] complexes (V, VI and VII, respectively) containing the "Os3C3" pentagonal pyramid cluster framework. Carbon 90-91 secreted phosphoprotein 1 Homo sapiens 106-110 15252576-3 2004 It was found that the diyne ligand easily reacts with all these complexes to give [HOs(3)(CO)8(PR3)-[mu3, eta1:eta3:eta1)-(CH(3)-C-C=CH-CH=C-O)]] complexes (V, VI and VII, respectively) containing the "Os3C3" pentagonal pyramid cluster framework. Carbon 90-91 secreted phosphoprotein 1 Homo sapiens 116-120 15252576-3 2004 It was found that the diyne ligand easily reacts with all these complexes to give [HOs(3)(CO)8(PR3)-[mu3, eta1:eta3:eta1)-(CH(3)-C-C=CH-CH=C-O)]] complexes (V, VI and VII, respectively) containing the "Os3C3" pentagonal pyramid cluster framework. Carbon 123-124 secreted phosphoprotein 1 Homo sapiens 106-110 15252576-3 2004 It was found that the diyne ligand easily reacts with all these complexes to give [HOs(3)(CO)8(PR3)-[mu3, eta1:eta3:eta1)-(CH(3)-C-C=CH-CH=C-O)]] complexes (V, VI and VII, respectively) containing the "Os3C3" pentagonal pyramid cluster framework. Carbon 123-124 secreted phosphoprotein 1 Homo sapiens 116-120 15252576-5 2004 In the case of the PEt(3) substituted cluster the second hydride transfer onto the organic fragment occurs to afford the nonhydride [Os(3)(CO)(8)(PR3)[mu3), eta1:eta2:eta1)-(CH(3)-CH-C=CH-CH=C-O)]] cluster, VIII, containing distorted pentagonal pyramid framework with a broken Os-C bond. Carbon 139-140 secreted phosphoprotein 1 Homo sapiens 157-161 15252576-5 2004 In the case of the PEt(3) substituted cluster the second hydride transfer onto the organic fragment occurs to afford the nonhydride [Os(3)(CO)(8)(PR3)[mu3), eta1:eta2:eta1)-(CH(3)-CH-C=CH-CH=C-O)]] cluster, VIII, containing distorted pentagonal pyramid framework with a broken Os-C bond. Carbon 139-140 secreted phosphoprotein 1 Homo sapiens 167-171 15268106-3 2004 We find that fluorine substituted aromatic rings are more ordered than unsubstituted aromatic rings by a factor of two based on the polarization dependence of the lowest C 1s to pi* transition, which is associated with transitions from phenyl carbons attached to hydrogens. Carbon 243-250 heterogeneous nuclear ribonucleoprotein C Homo sapiens 170-173 15136183-0 2004 An unmediated H2O2 biosensor based on the enzyme-like activity of myoglobin on multi-walled carbon nanotubes. Carbon 92-98 myoglobin Homo sapiens 66-75 15242227-1 2004 Optimisation of process parameters for adsorption of metal ions viz., Cu2+, Cd2+ and Ni2+ ions on Straw Carbon (SC) was carried out by using Box-Behnken statistics and analysis of variance methods. Carbon 104-110 CD2 molecule Homo sapiens 76-79 15073222-1 2004 In plants with Crassulacean acid metabolism, a diel separation of carboxylation processes mediated by phosphoenolpyruvate carboxylase (PEPC) and Rubisco optimizes photosynthetic performance and carbon gain in potentially limiting environments. Carbon 194-200 phosphoenolpyruvate carboxykinase 1 Homo sapiens 102-133 15073222-1 2004 In plants with Crassulacean acid metabolism, a diel separation of carboxylation processes mediated by phosphoenolpyruvate carboxylase (PEPC) and Rubisco optimizes photosynthetic performance and carbon gain in potentially limiting environments. Carbon 194-200 phosphoenolpyruvate carboxykinase 1 Homo sapiens 135-139 15038749-1 2004 We have obtained carbon-carbon bond length data for the functional retinylidene chromophore of rhodopsin, with a spatial resolution of 3 pm. Carbon 17-23 rhodopsin Bos taurus 95-104 15038749-1 2004 We have obtained carbon-carbon bond length data for the functional retinylidene chromophore of rhodopsin, with a spatial resolution of 3 pm. Carbon 24-30 rhodopsin Bos taurus 95-104 15282944-3 2004 Phosphoenol pyruvate carboxylase (PEPC) enzyme, which is responsible for carbon dioxide fixation in C4 and crassulacean acid metabolism plants, has also been found to play an important role in carbon metabolism in legume root nodule. Carbon 73-79 phosphoenolpyruvate carboxykinase 1 Homo sapiens 0-32 15282944-3 2004 Phosphoenol pyruvate carboxylase (PEPC) enzyme, which is responsible for carbon dioxide fixation in C4 and crassulacean acid metabolism plants, has also been found to play an important role in carbon metabolism in legume root nodule. Carbon 73-79 phosphoenolpyruvate carboxykinase 1 Homo sapiens 34-38 15282944-8 2004 Information on the relationship between nitrogen fixation and carbon metabolism through PEPC in leguminous plants is scanty and incoherent. Carbon 62-68 phosphoenolpyruvate carboxykinase 1 Homo sapiens 88-92 14652185-5 2003 Contour velocity plots for inelastic scattering of CD5+ from hydrocarbon-coated and hydrocarbon-free highly oriented pyrolytic graphite (HOPG) surfaces gave effective masses of the surface involved in the scattering event, approximately matching that of an ethyl group (or two methyl groups) and four to five carbon atoms, respectively. Carbon 66-72 CD5 molecule Homo sapiens 51-54 14658408-7 2003 RESULTS: The hs-CRP level was significantly higher in the ACS group (44.5 mg/l) than in the S group (2.1 mg/l) and the C group (0.6 mg/l) (p < 0.0001). Carbon 16-17 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Homo sapiens 58-61 14672363-3 2003 Both the cultures (C1 and C2) were able to utilize acrylonitrile up to a concentration of 2000 mg/l as the sole source of carbon and nitrogen. Carbon 122-128 heterogeneous nuclear ribonucleoprotein C Homo sapiens 19-28 14584684-1 2003 Gamma-aminobutyrate (GABA) is a ubiquitous four-carbon, non-protein amino acid synthesized by glutamate decarboxylase. Carbon 48-54 glutamate decarboxylase Nicotiana tabacum 94-117 12750857-1 2003 The pathways for 2,4-dinitrotoluene (2,4-DNT) and nitrobenzene offer fine illustrations of how the ability to assimilate new carbon sources evolves in bacteria. Carbon 125-131 5', 3'-nucleotidase, cytosolic Homo sapiens 41-44 12924577-3 2003 This general observation resulted in the acceptance of organic carbon normalized sorption coefficients (KOC) as unique properties or constants of organic chemicals. Carbon 63-69 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 104-107 12867442-5 2003 An adh mutant was constructed and found to be incapable of growth in media in which ethanol was both the carbon source and electron donor for sulfate reduction or was only the carbon source, with hydrogen serving as electron donor. Carbon 105-111 alcohol dehydrogenase 1A (class I), alpha polypeptide Homo sapiens 3-6 12867442-5 2003 An adh mutant was constructed and found to be incapable of growth in media in which ethanol was both the carbon source and electron donor for sulfate reduction or was only the carbon source, with hydrogen serving as electron donor. Carbon 176-182 alcohol dehydrogenase 1A (class I), alpha polypeptide Homo sapiens 3-6 12904537-1 2003 The methylotrophic yeast Candida boidinii exhibits S-formylglutathione hydrolase activity (FGH, EC 3.1.2.12), which is involved in the glutathione-dependent formaldehyde oxidation pathway during growth on methanol as the sole carbon source. Carbon 226-232 S-formylglutathione hydrolase Saccharomyces cerevisiae S288C 51-80 12700234-4 2003 Shm2p and Ade3p are cytoplasmic enzymes producing 5,10-methylene tetrahydrofolate in convergent pathways as the primary source for cellular one-carbon groups. Carbon 144-150 trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 Saccharomyces cerevisiae S288C 10-15 12854727-1 2003 The strength and the character of the binding of 14 organic solvents to the corn protein zein in distilled water and in various salt solutions were determined by preparing zein-coated carbon stationary phase and by measuring the retention characteristics of solvents on a high-performance liquid chromatographic column filled with this stationary phase. Carbon 184-190 zein Zea mays 89-93 12854727-1 2003 The strength and the character of the binding of 14 organic solvents to the corn protein zein in distilled water and in various salt solutions were determined by preparing zein-coated carbon stationary phase and by measuring the retention characteristics of solvents on a high-performance liquid chromatographic column filled with this stationary phase. Carbon 184-190 zein Zea mays 172-176 12790601-3 2003 The de is good for compounds with one substituent at the outer carbon of the double bond at C-2, but only one diastereomer is formed in cyclizations of compounds with two substituents at that position. Carbon 63-69 complement C2 Homo sapiens 92-95 12948139-2 2003 The cinder/ruthenium purple hybrid-modified carbon paste electrode (designated as CPE/CFe*-RP) was worked out for hydrodynamic analysis of H2O2 at a low detecting potential of 0.0 V versus Ag/AgCl in pH 7 ammonium buffer solution. Carbon 44-50 carboxypeptidase E Homo sapiens 82-85 12754701-4 2003 The cofactor is an unstable reduced pterin with a unique four-carbon side chain, synthesized by a complex pathway that requires the products of at least four different genes (MOCS1, MOCS2, MOCS3, and GEPH). Carbon 62-68 gephyrin Homo sapiens 200-204 12719378-2 2003 The biochemical signature of X-ALD is increased levels of saturated very long-chain fatty acids (VLCFA; carbon chains of 22 or more) in tissues and plasma that has been associated with decreased peroxisomal very long-chain acyl-CoA synthetase (VLCS) activity and decreased peroxisomal VLCFA beta-oxidation. Carbon 104-110 solute carrier family 27 (fatty acid transporter), member 2 Mus musculus 207-242 12775055-4 2003 Most of the remaining C and N content of RDX, MNX, and HMX was found in HCHO, N2O, HCOOH, and NH3. Carbon 22-23 keratin 86 Homo sapiens 46-49 12535554-6 2003 These effects were noted when the carbon fiber tip was mounted in a closed glass vacuum bulb pumped by barium getters, and also in a vacuum system using the combination of a molecular drag pump and ion pumps. Carbon 34-40 TOR signaling pathway regulator Homo sapiens 47-50 12535554-7 2003 The second type of enhancement occurs under ultrahigh vacuum conditions, during in situ thermal treatment of the carbon fiber tip while the emission current is about 2.5 microA. Carbon 113-119 TOR signaling pathway regulator Homo sapiens 126-129 12739670-0 2003 A novel approach to carbon hollow spheres and vessels from CCl4 at low temperatures. Carbon 20-26 C-C motif chemokine ligand 4 Homo sapiens 59-63 12739670-1 2003 Carbon hollow spheres (400-600 nm) and vessels (400 nm x 3000 nm) have been synthesized from sp3-CCl4 at 190 and 230 degrees C, respectively. Carbon 0-6 C-C motif chemokine ligand 4 Homo sapiens 97-101 12676598-5 2003 HO-1 expression, a sensitive marker for oxidative stress, is directly correlated with the high organic carbon and polycyclic aromatic hydrocarbon (PAH) content of UFPs. Carbon 103-109 heme oxygenase 1 Homo sapiens 0-4 7581178-3 1995 It employs carbon molecular sieves to adsorb 11CO2 selectively from gas targets at room temperature. Carbon 11-17 complement C2 Homo sapiens 47-50 7775433-0 1995 Double bond removal from odd-numbered carbons during peroxisomal beta-oxidation of arachidonic acid requires both 2,4-dienoyl-CoA reductase and delta 3,5,delta 2,4-dienoyl-CoA isomerase. Carbon 38-45 enoyl-CoA hydratase 1 Homo sapiens 144-185 7775433-8 1995 Our results show that the removal of double bonds from odd-numbered carbons in arachidonic acid thus requires both NADPH-dependent 2,4-dienoyl-CoA reductase and delta 3,5,delta 2,4-dienoyl-CoA isomerase. Carbon 68-75 enoyl-CoA hydratase 1 Homo sapiens 161-202 7900786-4 1995 70: 392-408, 1992) proposed a model of the citric acid cycle (CAC) in myocytes and a system of 17 differential equations that can be used to describe the changes over time in enrichment of carbons C-2 and C-4 of glutamate under conditions of metabolic steady state. Carbon 189-196 complement C2 Rattus norvegicus 197-200 7900786-9 1995 The formula for vTCA during administration of [2-13C]acetate is as follows: vTCA = M[(C-2ssLC-4)/[C-4ss(LC-4-LC-2)]], where C-2ss and C-4ss represent steady-state fractional enrichment, LC-2 and LC-4 represent dominant rate constants of C-2 and C-4 of glutamate, respectively, and M is the sum of concentrations of aspartate, glutamate, and intermediates of the CAC. Carbon 18-19 complement C2 Rattus norvegicus 86-89 7614556-7 1995 occidentalis hexokinase by gene replacement yielded a mutant unable to grow on fructose as sole carbon source, but still growing on glucose. Carbon 96-102 hexokinase Saccharomyces cerevisiae S288C 13-23 7828914-8 1995 Gene disruption shows the MRP-L4 product to be indispensable for mt function in cells growing on non-fermentable carbon sources. Carbon 113-119 mitochondrial 54S ribosomal protein YmL4 Saccharomyces cerevisiae S288C 26-32 7828914-9 1995 In contrast to nearly all other MRPs investigated so far, gene disruption of MRP-L4 also affects growth of yeast cells on fermentable carbon sources, suggesting additional cytosolic and/or mt functions of YmL4 besides its involvement in mt protein biosynthesis. Carbon 134-140 mitochondrial 54S ribosomal protein YmL4 Saccharomyces cerevisiae S288C 77-83 7696881-7 1995 In support of this hypothesis, we show that, on restimulation of suspension-cultured cells, cyclin delta 3 is rapidly induced by the plant growth regulator cytokinin and cyclin delta 2 is induced by carbon source. Carbon 199-205 proliferating cell nuclear antigen Homo sapiens 170-176 7986072-1 1994 The cytosolic isozyme of malate dehydrogenase, MDH2, was previously shown to be subject to rapid inactivation and proteolysis following the addition of glucose to yeast cultures growing on nonfermentable carbon sources. Carbon 204-210 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 47-51 7969120-2 1994 Using an ethyl methanesulfonate mutant of a yeast strain in which CUP1 and ACE1 were deleted, we isolated a gene, designated CUP9, which permits yeast cells to grow at high concentrations of environmental copper, most notably when lactate is the sole carbon source. Carbon 251-257 Cup2p Saccharomyces cerevisiae S288C 75-79 7812153-0 1994 Resonance assignment of methionine methyl groups and chi 3 angular information from long-range proton-carbon and carbon-carbon J correlation in a calmodulin-peptide complex. Carbon 102-108 chitinase 1 Homo sapiens 53-58 7812153-0 1994 Resonance assignment of methionine methyl groups and chi 3 angular information from long-range proton-carbon and carbon-carbon J correlation in a calmodulin-peptide complex. Carbon 113-119 chitinase 1 Homo sapiens 53-58 7812153-0 1994 Resonance assignment of methionine methyl groups and chi 3 angular information from long-range proton-carbon and carbon-carbon J correlation in a calmodulin-peptide complex. Carbon 113-119 chitinase 1 Homo sapiens 53-58 7921463-10 1994 And like DPPC, the analogs interacted with isolated SP-B+C and improved in vivo function to levels comparable to LES. Carbon 12-13 pulmonary surfactant-associated protein B Oryctolagus cuniculus 52-56 16349415-1 1994 A color variant strain of Aureobasidium pullulans (NRRL Y-12974) produced beta-glucosidase activity when grown in liquid culture on a variety of carbon sources, such as cellobiose, xylose, arabinose, lactose, sucrose, maltose, glucose, xylitol, xylan, cellulose, starch, and pullulan. Carbon 145-151 beta-glucosidase Zea mays 74-90 8206942-8 1994 Faa3p has a preference for C16 and C18 fatty acids with a cis-double bond at C-9-C-10. Carbon 27-28 long-chain fatty acid-CoA ligase FAA3 Saccharomyces cerevisiae S288C 0-5 8206942-8 1994 Faa3p has a preference for C16 and C18 fatty acids with a cis-double bond at C-9-C-10. Carbon 35-36 long-chain fatty acid-CoA ligase FAA3 Saccharomyces cerevisiae S288C 0-5 16349303-2 1994 Carbon mineralization studies with both unlabeled (TNT, 2,4-DNT, and 2,6-DNT) and radiolabeled ([C]TNT) substrates indicated that a significant fraction of these source compounds was degraded to CO(2). Carbon 0-6 5', 3'-nucleotidase, cytosolic Homo sapiens 60-63 16349303-2 1994 Carbon mineralization studies with both unlabeled (TNT, 2,4-DNT, and 2,6-DNT) and radiolabeled ([C]TNT) substrates indicated that a significant fraction of these source compounds was degraded to CO(2). Carbon 0-6 5', 3'-nucleotidase, cytosolic Homo sapiens 73-76 8155659-0 1994 Mechanism of the acyl-carbon cleavage and related reactions catalyzed by multifunctional P-450s: studies on cytochrome P-450(17)alpha. Carbon 22-28 cytochrome P450 family 2 subfamily D member 6 Sus scrofa 108-124 8159114-2 1994 Skeletal muscle intracellular pH (pHi) was measured using magnetic resonance spectroscopy from the chemical shift of the carbon-2 (C2) proton resonance of the imidazole ring of anserine. Carbon 121-127 glucose-6-phosphate isomerase Rattus norvegicus 34-37 9910608-0 1994 Erratum: Fusion yields for carbon-cluster impact on CD2 targets Carbon 27-33 CD2 molecule Homo sapiens 52-55 7509633-6 1994 The results indicate that the covalently coupled fatty acid is highly immobilized near the carboxyl terminus because double quadrupolar splittings and very low T1 values (4 ms) were found for the -CD2- deuterons at carbon atoms C2 and C3. Carbon 215-221 CD2 molecule Homo sapiens 197-200 7908717-2 1994 We have isolated a mutant, termed acr1, defective for this activity by screening for mutants unable to utilize ethanol as a sole carbon source. Carbon 129-135 Arr1p Saccharomyces cerevisiae S288C 34-38 8017099-6 1994 High activity of the CUP1 promoter was observed on both a fermentable (glucose) and a non-fermentable (ethanol) carbon source. Carbon 112-118 metallothionein CUP1 Saccharomyces cerevisiae S288C 21-25 8152377-5 1994 Moreover, the uspA mutation results in an increased sensitivity of cells to carbon-source starvation (i.e. glucose, glycerol or succinate depletion). Carbon 76-82 putative universal stress protein UspA Escherichia coli 14-18 8264590-3 1994 This downstream region, inserted upstream of a promoterless CYC1::lacZ fusion, activated gene expression in a carbon source-dependent manner by a factor of 15 to 111, independent of orientation. Carbon 110-116 cytochrome c isoform 1 Saccharomyces cerevisiae S288C 60-64 7838896-4 1994 The sensitivity of the technique was confirmed by observing chemical shift differences between these two experimental conditions of the amino carbons (C-2"s) of glutamate, glutamine, N-carbamoylaspartate and aspartate. Carbon 142-149 complement C2 Rattus norvegicus 151-154 8251125-6 1993 The molecular distortion in the Pbca polymorph is also larger than that in the Pnaa polymorph; this distortion is evidenced by torsion angles (13-20 degrees) in the bay region and by an out-of-plane displacement (0.8 A) of the C atom of the methylene portion of the ethyl group [the C atom attached to C(11)]. Carbon 227-228 PBCA Homo sapiens 32-36 8251125-6 1993 The molecular distortion in the Pbca polymorph is also larger than that in the Pnaa polymorph; this distortion is evidenced by torsion angles (13-20 degrees) in the bay region and by an out-of-plane displacement (0.8 A) of the C atom of the methylene portion of the ethyl group [the C atom attached to C(11)]. Carbon 283-284 PBCA Homo sapiens 32-36 8221926-6 1993 Furthermore TYE2 function seems to be important for the expression of a variety of Ty-unrelated functions such as ADH1 expression, sporulation, growth on maltose, galactose, raffinose, and on non-fermentable carbon sources. Carbon 208-214 Swi3p Saccharomyces cerevisiae S288C 12-16 27519880-5 1993 DGAT activity in the membrane fraction was traced in fungi cultured for different time periods or in media at different carbon to nitrogen (C/N) ratios. Carbon 120-126 diacylglycerol O-acyltransferase 1 Homo sapiens 0-4 27519880-5 1993 DGAT activity in the membrane fraction was traced in fungi cultured for different time periods or in media at different carbon to nitrogen (C/N) ratios. Carbon 140-141 diacylglycerol O-acyltransferase 1 Homo sapiens 0-4 8500273-6 1993 In the same animals, anti-LFA-1 partially (35-50%) inhibited PMNL accumulation in acute dermal inflammation induced by zymosan-activated serum (ZAS, C5ades Arg), IL-1 or endotoxin (P < 0.01) and suppressed T lymphocyte migration to dermal DTH, IFN-gamma, LPS, and poly-I:C-induced inflammation by 60-80%. Carbon 149-150 integrin subunit alpha L Rattus norvegicus 26-31 8318164-5 1993 We have previously constructed the three-dimensional structure of the p21 protein bound to GDP from an available alpha-carbon tracing of this protein using a combination of molecular dynamics and energy minimization (Dykes, et al., J. Biomol. Carbon 119-125 H3 histone pseudogene 16 Homo sapiens 70-73 24190642-2 1993 The transamination by tyrosine aminotransferase (TAT) needs the presence in the substrate molecule of free amino and carboxylic groups, a three-carbon aliphatic chain, a para-phenolic hydroxylic function and aL-configuration. Carbon 144-150 tyrosine aminotransferase Rattus norvegicus 22-47 24190642-2 1993 The transamination by tyrosine aminotransferase (TAT) needs the presence in the substrate molecule of free amino and carboxylic groups, a three-carbon aliphatic chain, a para-phenolic hydroxylic function and aL-configuration. Carbon 144-150 tyrosine aminotransferase Rattus norvegicus 49-52 1433514-2 1992 An antibody (C"-B5R) raised to a 15-amino-acid peptide from the translated B5R ORF reacted with a 42-kDa protein (gp42) found in vaccinia virus-infected cells and cesium chloride-banded EEV but not INV. Carbon 13-15 leishmanolysin like peptidase Homo sapiens 198-201 1390771-2 1992 In vivo TS binds a polyglutamyl cofactor, polyglutamyl methylenetetrahydrofolate (CH2-H4folate), which serves as a carbon donor. Carbon 115-121 thymidylate synthetase Homo sapiens 8-10 1324416-0 1992 ABF1 is a phosphoprotein and plays a role in carbon source control of COX6 transcription in Saccharomyces cerevisiae. Carbon 45-51 cytochrome c oxidase subunit VI Saccharomyces cerevisiae S288C 70-74 1324416-11 1992 Transcription of COX6 is repressed by growth in medium containing a fermentable carbon source and is derepressed by growth in medium containing a nonfermentable carbon source. Carbon 80-86 cytochrome c oxidase subunit VI Saccharomyces cerevisiae S288C 17-21 1324416-11 1992 Transcription of COX6 is repressed by growth in medium containing a fermentable carbon source and is derepressed by growth in medium containing a nonfermentable carbon source. Carbon 161-167 cytochrome c oxidase subunit VI Saccharomyces cerevisiae S288C 17-21 12684383-4 2003 Nevertheless, hH1 mutants had mycelial elongation rates that were lower than normal on all tested carbon sources. Carbon 98-104 H1.5 linker histone, cluster member Homo sapiens 14-17 12685706-2 2003 A biphasic pattern was observed in the relationship between the log of the carbon-normalized sorption distribution coefficient (Koc) and the volumetric fraction of water-miscible cosolvent (fc), in this case methanol, that was accounted for with phenanthrene solubility data. Carbon 75-81 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 128-131 12685707-1 2003 An improvement of a method for determination of the distribution coefficient for polycyclic aromatic compounds (PAC) between organic carbon and water (Koc) by high-performance liquid chromatography (HPLC) is presented in this paper. Carbon 133-139 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 151-154 12713417-2 2003 Trisphaerolide A (1) has a putative polyketide biogenesis, incorporating a rare variant on the standard pathway, which involves the addition of methyl branches arising from C-2 carbons of acetate units to chain carbons that arise from C-1 of acetate units. Carbon 177-184 complement C2 Homo sapiens 173-176 12713417-2 2003 Trisphaerolide A (1) has a putative polyketide biogenesis, incorporating a rare variant on the standard pathway, which involves the addition of methyl branches arising from C-2 carbons of acetate units to chain carbons that arise from C-1 of acetate units. Carbon 211-218 heterogeneous nuclear ribonucleoprotein C Homo sapiens 235-238 31959127-6 2020 Whole-exome sequencing of the proband revealed a novel nonsense variant in TAB2 (c.C446G, p.S149X), which results in the elimination of the majority of C-terminal amino acids of TAB2, including the critical TAK1-binding domain. Carbon 83-84 mitogen-activated protein kinase kinase kinase 7 Homo sapiens 207-211 12496284-2 2003 Ligand fishing experiments in HEK293 cells expressing human GPR40 revealed that a range of saturated and unsaturated carboxylic acids with carbon chain lengths greater than six were able to induce an elevation of [Ca(2+)](i), measured using a fluorometric imaging plate reader. Carbon 139-145 free fatty acid receptor 1 Homo sapiens 60-65 1637501-3 1992 A complete three-dimensional structure for the ras-gene-encoded p21 protein with Gly 12 and Gln 61, bound to GDP, has been constructed in four stages using the available alpha-carbon coordinates as deposited in the Brookhaven National Laboratories Protein Data Bank. Carbon 176-182 H3 histone pseudogene 16 Homo sapiens 64-67 1314953-1 1992 Transcription of the Saccharomyces cerevisiae COX6 gene is regulated by heme and carbon source. Carbon 81-87 cytochrome c oxidase subunit VI Saccharomyces cerevisiae S288C 46-50 31742997-0 2020 Adoption of a Turn Conformation Drives the Binding Affinity of p53 C-Terminal Domain Peptides to 14-3-3sigma. Carbon 19-20 stratifin Homo sapiens 97-108 31919731-3 2020 Here, we successfully introduced N, C co-doped MoP (MoP-NC) nanoparticles by a simple and efficient two-step synthesis method using urea as a carbon source into the molybdenum phosphide system. Carbon 142-148 opioid receptor mu 1 Homo sapiens 47-50 1325688-9 1992 Energetically, the decreased potency can be accounted for by the loss of two hydrogen bonds, one at the C-13 -OH of dcSTX, and the other at the amino group in the carbamoyl function of STX. Carbon 104-105 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 Rattus norvegicus 118-121 12633750-8 2003 This is followed by oxygen transfer to the most electropositive carbon atoms, C-6, C-1, and C-3, with formation of 6-OHBP (and its quinones), 1-OHBP, and 3-OHBP, respectively, or the most electropositive 4,5-, 7,8-, and 9,10- double bonds, with formation of BP 4,5-, 7,8-, or 9,10-oxide. Carbon 64-70 complement C6 Rattus norvegicus 78-81 31919731-3 2020 Here, we successfully introduced N, C co-doped MoP (MoP-NC) nanoparticles by a simple and efficient two-step synthesis method using urea as a carbon source into the molybdenum phosphide system. Carbon 142-148 opioid receptor mu 1 Homo sapiens 52-58 12908248-2 2003 At lower bias voltage, the emission current of the coated nanotube is comparable to that of the bare carbon nanotube and is dominated by the contribution from localized states at the tip of the tube. Carbon 101-107 TOR signaling pathway regulator Homo sapiens 183-186 12908248-3 2003 At higher voltage, newly generated hybridized states between the carbon nanotube tip and the even-membered boron nitride rings contribute significantly to the emission current because they experience a low tunneling barrier compared with the bare carbon nanotube case. Carbon 65-71 TOR signaling pathway regulator Homo sapiens 81-84 1561839-1 1992 The IMP2 gene of Saccharomyces cerevisiae is involved in the nucleo-mitochondrial control of maltose, galactose and raffinose utilization as shown by the inability of imp2 mutants to grow on these carbon sources in respiratory-deficient conditions or in the presence of ethidium bromide and erythromycin. Carbon 197-203 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 4-8 1561839-2 1992 The negative phenotype cannot be scored in the presence of inhibitors of respiration and oxidative phosphorylation, indicating that the role of the mitochondria in the utilization of the above-mentioned carbon sources in imp2 mutants is not at the energetical level. Carbon 203-209 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 221-225 31919731-4 2020 The cheapness of urea and the excellent carbon to nitrogen ratio remove the obstacles ahead of the development of MoP-NC composites. Carbon 40-46 opioid receptor mu 1 Homo sapiens 114-120 1561839-3 1992 Mutations in the IMP2 gene also confer many phenotypic alterations in respiratory-sufficient conditions, e.g. leaky phenotype on oxidizable carbon sources, sensitivity to heat shock and sporulation deficiency. Carbon 140-146 endopeptidase catalytic subunit Saccharomyces cerevisiae S288C 17-21 31936622-6 2020 From the series, compounds 7 and 11 with a 10-carbon chain can be viewed as multi-target leads for the treatment of AD, as they act as dual and bifunctional cholinesterase inhibitors and prevent the neuronal damage caused by diverse aggressors related to protein misfolding and aggregation, iron accumulation and excitotoxicity. Carbon 46-52 butyrylcholinesterase Homo sapiens 157-171 1735693-2 1992 The lead compound in this series, NLP-1, is a 2-nitroimidazole, linked at the one position to a phenanthridine ring system via a three carbon chain. Carbon 135-141 nucleoporin 42 Homo sapiens 34-39 12908248-3 2003 At higher voltage, newly generated hybridized states between the carbon nanotube tip and the even-membered boron nitride rings contribute significantly to the emission current because they experience a low tunneling barrier compared with the bare carbon nanotube case. Carbon 247-253 TOR signaling pathway regulator Homo sapiens 81-84 12527817-11 2003 All of the compounds inhibited COX-1 and demonstrated progressively greater COX-1 selectivity with increasing number of carbons. Carbon 120-127 mitochondrially encoded cytochrome c oxidase I Homo sapiens 76-81 31909713-4 2020 Drg1-ATPase activity removes Rlp24 from the GTPase Nog1 on the pre-60S; consequently, the C-terminal tail of Nog1 is extracted from the PET. Carbon 90-91 developmentally regulated GTP binding protein 1 Homo sapiens 0-4 31909713-4 2020 Drg1-ATPase activity removes Rlp24 from the GTPase Nog1 on the pre-60S; consequently, the C-terminal tail of Nog1 is extracted from the PET. Carbon 90-91 GTP binding protein 4 Homo sapiens 51-55 31909713-4 2020 Drg1-ATPase activity removes Rlp24 from the GTPase Nog1 on the pre-60S; consequently, the C-terminal tail of Nog1 is extracted from the PET. Carbon 90-91 GTP binding protein 4 Homo sapiens 109-113 12745668-1 2003 The synthetic compound NO-1886 is a lipoprotein lipase activator that lowers plasma triglycerides and elevates high-density lipoprotein cholesterol (HDL-C). Carbon 153-154 lipoprotein lipase Oryctolagus cuniculus 36-54 1655793-1 1991 The regulatory subunit of cAMP-dependent protein kinase in yeast, encoded by the BCY1 gene, is known to be required under certain conditions such as growth on nonfermentable carbon sources and entry into stationary phase. Carbon 174-180 cAMP-dependent protein kinase regulatory subunit BCY1 Saccharomyces cerevisiae S288C 81-85 33134006-1 2020 Background: Green Infrastructure (GI) is defined as a strategically planned network of natural and semi-natural spaces that provide society, in both rural and urban areas, with a large number of goods and services of great value and economic importance such as clean air and water, carbon storage, pollination or protection against the effects of climate change. Carbon 282-288 G protein subunit alpha i1 Homo sapiens 34-36 1838313-4 1991 We suggest that the C17 side chain is involved in protein binding and subsequent presentation of antigenic sites on the carbon rings. Carbon 120-126 cytokine like 1 Homo sapiens 20-23 12511494-1 2003 Sulfolobus solfataricus secretes an acid-resistant alpha-amylase (amyA) during growth on starch as the sole carbon and energy source. Carbon 108-114 glycoside hydrolase family 57 protein Saccharolobus solfataricus 51-64 12511494-1 2003 Sulfolobus solfataricus secretes an acid-resistant alpha-amylase (amyA) during growth on starch as the sole carbon and energy source. Carbon 108-114 glycoside hydrolase family 57 protein Saccharolobus solfataricus 66-70 32192644-1 2020 BACKGROUND: The 24-week randomized, double-blind ODYSSEY ALTERNATIVE trial (NCT01709513) demonstrated significant low-density lipoprotein cholesterol (LDL-C) reductions with the PCSK9 inhibitor alirocumab vs ezetimibe in statin-intolerant patients, with significantly fewer skeletal muscle events (SMEs; 32.5%) vs atorvastatin (46.0%; hazard ratio: 0.61, 95% confidence interval: 0.38 to 0.99, P = .042). Carbon 2-3 proprotein convertase subtilisin/kexin type 9 Homo sapiens 178-183 12511494-8 2003 The amyA::lacS mutant lost the ability to grow on starch, glycogen, or pullulan as sole carbon and energy sources. Carbon 88-94 glycoside hydrolase family 57 protein Saccharolobus solfataricus 4-8 12509145-4 2003 The mean dipole moment derivative (GAPT charge) of the methyl carbon in CH3NC, 0.347 e, is between the corresponding values in CH3CN, 0.110 e, and CH3F, 0.541 e. The mean dipole moment derivatives obtained here indicate the correct 1s methyl carbon ionization energy as 293.35 eV which is 0.98 eV higher than the corresponding ionization energy of the terminal atom. Carbon 62-68 GRB2 binding adaptor protein, transmembrane Homo sapiens 35-39 16348538-2 1991 Spore-forming rods dominated in the enrichments when lactate, propionate, butyrate, or a mixture of aliphatic fatty acids (C(4) through C(6)) was added as a carbon source and electron donor. Carbon 157-163 complement C4A (Rodgers blood group) Homo sapiens 123-127 31791492-5 2020 Moreover, 1 mug/mL to 10 mug/mL carbon particle treatments disrupted the keratinocyte differentiation, and up-regulated inflammation- and psoriasis-related genes, such as IL-1beta, IL-6, CXCL1, CXCL2, CXCL3, CCL20, CXCL8, and S100A7 and S100A9, respectively. Carbon 32-38 interleukin 1 alpha Homo sapiens 171-179 1680851-8 1991 The low affinity of Im for DAO may be due to a steric repulsion of the hydrogen atoms of Im at C(3) in the active site. Carbon 95-96 D-amino acid oxidase Homo sapiens 27-30 12509145-4 2003 The mean dipole moment derivative (GAPT charge) of the methyl carbon in CH3NC, 0.347 e, is between the corresponding values in CH3CN, 0.110 e, and CH3F, 0.541 e. The mean dipole moment derivatives obtained here indicate the correct 1s methyl carbon ionization energy as 293.35 eV which is 0.98 eV higher than the corresponding ionization energy of the terminal atom. Carbon 242-248 GRB2 binding adaptor protein, transmembrane Homo sapiens 35-39 31791492-5 2020 Moreover, 1 mug/mL to 10 mug/mL carbon particle treatments disrupted the keratinocyte differentiation, and up-regulated inflammation- and psoriasis-related genes, such as IL-1beta, IL-6, CXCL1, CXCL2, CXCL3, CCL20, CXCL8, and S100A7 and S100A9, respectively. Carbon 32-38 C-X-C motif chemokine ligand 2 Homo sapiens 194-199 12487320-6 2002 Approximately 4.9 x 10(8) t of refuse was disposed in NYC during the 20th century (including commercial and residential refuse), representing a total pool of about 8.0 x 10(7) t of organic carbon (as C) that has entered city landfills and incinerators. Carbon 189-195 steroid sulfatase Homo sapiens 197-201 16668030-4 1991 At the onset of light, a delay observed for guard cell protoplasts between O(2) evolution and CO(2) fixation and a time lag before the rate of saturation suggested a carbon metabolism based on phosphoenolpyruvate carboxylase activity. Carbon 166-172 phosphoenolpyruvate carboxykinase 1 Homo sapiens 193-224 31339073-5 2020 RESULTS: To evaluate interaction energies found that the Lys58 is essential for the union of the analogs to the active site of Hsp90, and that the activity of these will depend on if these have on the C-11 position of the macrocycle a group of small and at the same time attractor of electrons, as it is reflected with the series C-11 hydroxy and methoxy C-11. Carbon 201-202 heat shock protein 90 alpha family class A member 1 Homo sapiens 127-132 2010659-3 1991 All 6 GM-CSF-expressing leukemia samples simultaneously displayed high levels of transcripts for the c-fes proto-oncogene previously shown to be expressed in GM-CSF sensitive myeloid cells, whereas only 2 of the 48 AML samples not expressing GM-CSF accumulated c-fes mRNA. Carbon 86-87 colony stimulating factor 2 Homo sapiens 6-12 2010659-3 1991 All 6 GM-CSF-expressing leukemia samples simultaneously displayed high levels of transcripts for the c-fes proto-oncogene previously shown to be expressed in GM-CSF sensitive myeloid cells, whereas only 2 of the 48 AML samples not expressing GM-CSF accumulated c-fes mRNA. Carbon 86-87 colony stimulating factor 2 Homo sapiens 158-164 2010659-3 1991 All 6 GM-CSF-expressing leukemia samples simultaneously displayed high levels of transcripts for the c-fes proto-oncogene previously shown to be expressed in GM-CSF sensitive myeloid cells, whereas only 2 of the 48 AML samples not expressing GM-CSF accumulated c-fes mRNA. Carbon 86-87 colony stimulating factor 2 Homo sapiens 158-164 31339073-5 2020 RESULTS: To evaluate interaction energies found that the Lys58 is essential for the union of the analogs to the active site of Hsp90, and that the activity of these will depend on if these have on the C-11 position of the macrocycle a group of small and at the same time attractor of electrons, as it is reflected with the series C-11 hydroxy and methoxy C-11. Carbon 330-331 heat shock protein 90 alpha family class A member 1 Homo sapiens 127-132 31871320-6 2020 As a result, FoxO1 and PGC-1alpha cooperatively upregulate Pck1 expression, therefore directing the carbon flow along the gluconeogenic pathway to glycogen and the pentose phosphate pathway. Carbon 100-106 phosphoenolpyruvate carboxykinase 1 Homo sapiens 59-63 2254303-1 1990 1-14C-Labeled hepoxillin A3 is transformed by a purified preparation of glutathione S-transferase in the presence of glutathione into a glutathionyl conjugate in which the glutathione is covalently coupled to the carbon 11 position of hepoxilin A3. Carbon 213-219 hematopoietic prostaglandin D synthase Rattus norvegicus 72-97 31776255-9 2019 Because of the directionality of protein synthesis, this energetic dependency of domain III on its C-terminal neighbors disrupts cotranslational folding and imposes a posttranslational mechanism on the folding of the C-terminal part of EF-G. Carbon 99-100 G elongation factor mitochondrial 1 Homo sapiens 236-240 1983156-1 1990 Rat aorta semicarbazide-sensitive amine oxidase (SSAO) exhibits very high affinity in the deamination of an homologous series of aliphatic amines of 1 to 18 straight chain carbon atoms. Carbon 172-178 amine oxidase, copper containing 3 Rattus norvegicus 10-47 1983156-1 1990 Rat aorta semicarbazide-sensitive amine oxidase (SSAO) exhibits very high affinity in the deamination of an homologous series of aliphatic amines of 1 to 18 straight chain carbon atoms. Carbon 172-178 amine oxidase, copper containing 3 Rattus norvegicus 49-53 31776255-9 2019 Because of the directionality of protein synthesis, this energetic dependency of domain III on its C-terminal neighbors disrupts cotranslational folding and imposes a posttranslational mechanism on the folding of the C-terminal part of EF-G. Carbon 217-218 G elongation factor mitochondrial 1 Homo sapiens 236-240 33417790-6 2019 The Sil-MA water solution with the addition of a photoinitiator (LAP) allows the opening, under UV radiation, of a double carbon-carbon bond and radical polymerization. Carbon 129-135 LAP Homo sapiens 65-68 2233711-2 1990 This trifunctional enzyme, encoded by the ADE3 gene in the yeast Saccharomyces cerevisiae, is thought to be responsible for the synthesis of the one-carbon donor 10-formyl-THF for de novo purine synthesis. Carbon 149-155 trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 Saccharomyces cerevisiae S288C 42-46 31819058-1 2019 Human myeloid-derived growth factor (hMYDGF) is a 142-residue protein with a C-terminal endoplasmic reticulum (ER) retention sequence (ERS). Carbon 77-78 myeloid derived growth factor Homo sapiens 37-43 2204622-9 1990 Of the total carbon from the three major precursors entering the liver as C-6, D-glucose contributed 82%, while alanine and lactate contributed 18% at 20 min. Carbon 13-19 complement C6 Rattus norvegicus 74-77 31651092-1 2019 The exponentially increasing viscosity of water-lean CO 2 absorbents during carbon capture process is the vital problem for practical application, due to its strong correlation with system"s mass transfer as well as convenience of transportation. Carbon 76-82 complement C2 Homo sapiens 53-57 2246616-7 1990 Keratinocyte SPT utilizes palmitoyl-CoA preferentially over other saturated or unsaturated acyl-CoA substrates; increasing acyl-CoA chain lengths above C16 by one or two carbons was less detrimental to activity than similar decrements in chain length. Carbon 170-177 alanine--glyoxylate and serine--pyruvate aminotransferase Homo sapiens 13-16 2224886-1 1990 Extension of the carbon spine of 2,3;4,5-di-O-isopropylidene-beta-D-fructopyranoside by oxidation at C-1 followed by a Wittig reaction using the phosphorane Ph3P = CHCO2Et gave an oct-4-ulose derivative, which was then transformed into the key intermediate 1-azido-1,2,3-trideoxy-D-arabino-oct-4-ulose. Carbon 17-23 heterogeneous nuclear ribonucleoprotein C Homo sapiens 101-104 31805132-0 2019 Short-term treatment with a peroxisome proliferator-activated receptor alpha agonist influences plasma one-carbon metabolites and B-vitamin status in rats. Carbon 107-113 peroxisome proliferator activated receptor alpha Rattus norvegicus 28-76 31867560-3 2019 The spin-lattice relaxation time is long for C35, C6, C5, and C34 carbon nuclei that participated in the 1, 2, 4-triazole ring. Carbon 66-72 migration and invasion enhancer 1 Homo sapiens 45-48 2199324-1 1990 Expression of the S. cerevisiae gene, GCY, encoding a 35-kDa protein with striking homology to mammalian aldo/keto reductases, is under the control of galactose: the intracellular concentration of the respective mRNA (about 1300 nt in length) varies strongly with the carbon source. Carbon 268-274 GCY Homo sapiens 38-41 31714564-2 2019 The reactions with boranes BX3 SMe2 (X = H, Cl, Br), BF3 OEt2 and BCl3 yield Lewis adducts [BICAAC BH3] (1), [BICAAC BHCl2] (2), [BICAAC BH2Cl] (3), [BICAAC BF3] (4), [BICAAC BCl3] (5) and [BICAAC BBr3] (6) respectively, whereas more hydridic boranes, 9-borabicyclo[3.3.1]nonane (9-BBN) and catecholborane (HBcat), enable the insertion of the carbene carbon into the B-H bond to form [BICAAC(H)-(9-BBN)] (7) and [BICAAC(H)-Bcat] (8). Carbon 351-357 BCL3 transcription coactivator Homo sapiens 66-70 33775647-8 2021 Furthermore, the result from DiI-LDL uptake assay under the knockdown of PCSK9 demonstrated that miR-337-3p promoting the absorption of LDL-C in HepG2 cells was dependent on PCSK9, and the result from LDLR-/- mouse model indicated that miR-337-3p regulating LDL-C was dependent on PCSK9/LDLR pathway. Carbon 139-141 proprotein convertase subtilisin/kexin type 9 Homo sapiens 73-78 33775647-8 2021 Furthermore, the result from DiI-LDL uptake assay under the knockdown of PCSK9 demonstrated that miR-337-3p promoting the absorption of LDL-C in HepG2 cells was dependent on PCSK9, and the result from LDLR-/- mouse model indicated that miR-337-3p regulating LDL-C was dependent on PCSK9/LDLR pathway. Carbon 139-141 proprotein convertase subtilisin/kexin type 9 Homo sapiens 174-179 33775647-8 2021 Furthermore, the result from DiI-LDL uptake assay under the knockdown of PCSK9 demonstrated that miR-337-3p promoting the absorption of LDL-C in HepG2 cells was dependent on PCSK9, and the result from LDLR-/- mouse model indicated that miR-337-3p regulating LDL-C was dependent on PCSK9/LDLR pathway. Carbon 139-141 low density lipoprotein receptor Homo sapiens 201-205 33775647-8 2021 Furthermore, the result from DiI-LDL uptake assay under the knockdown of PCSK9 demonstrated that miR-337-3p promoting the absorption of LDL-C in HepG2 cells was dependent on PCSK9, and the result from LDLR-/- mouse model indicated that miR-337-3p regulating LDL-C was dependent on PCSK9/LDLR pathway. Carbon 139-141 proprotein convertase subtilisin/kexin type 9 Mus musculus 174-179 31794565-4 2019 In studies to identify regions of MARKs that confer catalytic activity towards variant sites, we found that the C-terminal kinase associated-1 (KA1) domain in MARK1-3 mediates binding to microtubule-associated proteins CLASP1/2; but this interaction is dispensable for zetaXKXGSXXNPsi phosphorylation. Carbon 112-113 cytoplasmic linker associated protein 1 Homo sapiens 219-227 33725138-1 2021 The transcription factors Cat8 and Sip4 were described in Saccharomyces cerevisiae and Kluyveromyces lactis to have very similar DNA binding domains and to be necessary for derepression of a variety of genes under non-fermentative growth conditions via binding to the carbon source responsive elements (CSREs). Carbon 268-274 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 26-30 31518817-2 2019 In order to effectively remove the ARS form dyeing wastewater, polyethyleneimine (PEI)-functionalized magnetic carbon nanotubes (PEI@MCNTs) adsorbent was successfully prepared and its adsorption performances were also investigated in detail. Carbon 111-117 secreted LY6/PLAUR domain containing 1 Homo sapiens 35-38 33777935-8 2021 Deregulated tumor cholesterogenesis at the HMGR locus, generating enhanced carbon flux through the cholesterol synthesis pathway, is an absolute prerequisite for DNA synthesis and cell division. Carbon 75-81 high mobility group AT-hook 1 Homo sapiens 43-47 33590399-0 2021 Adsorption mechanism of Zn2+, Ni2+, Cd2+, and Cu2+ ions by carbon-based adsorbents: interpretation of the adsorption isotherms via physical modelling. Carbon 59-65 CD2 molecule Homo sapiens 36-39 31573043-13 2019 The level of red fluorescence was observed prior to and following the administration of G418 using antibodies targeting the N- or C-terminus of the HERG protein. Carbon 130-131 potassium voltage-gated channel subfamily H member 2 Homo sapiens 148-152 33590399-1 2021 A theoretical physicochemical and thermodynamic investigation of the adsorption of heavy metals Zn2+, Cd2+, Ni2+, and Cu2+on carbon-based adsorbents was performed with statistical physics fundaments. Carbon 125-131 CD2 molecule Homo sapiens 102-105 34785054-3 2022 Here, binary heterogeneous nanocomplexes constructed from silver nanoparticles and carbon nanomaterials (termed as C-Ag NPs) were reported. Carbon 83-89 steroid sulfatase Homo sapiens 112-116 31543487-2 2019 The seasonal variation in sea surface temperature (SST)-normalized fCO2SW in the study area was largely explained by sea surface concentrations of dissolved inorganic carbon modulated by the water column stability in association with biological carbon fixation and remineralization. Carbon 167-173 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 4-7 34627018-4 2022 The number of surrounding BN strings (NBN) necessary to "isolate" the optical modes of a carbon nanoisland (nanographene) from the remaining substrate has been characterized in two different nanoisland models: benzene and pyrene. Carbon 89-95 nibrin Homo sapiens 38-41 34627018-5 2022 It was found that for NBN >= 3 the excitation wavelengths of the optically active modes remain constant and the changes in the transition densities, the ground to excited state density differences and their associated electron deformation orbitals are negligible and strongly confined within the carbon nanoisland. Carbon 296-302 nibrin Homo sapiens 22-25 31543487-2 2019 The seasonal variation in sea surface temperature (SST)-normalized fCO2SW in the study area was largely explained by sea surface concentrations of dissolved inorganic carbon modulated by the water column stability in association with biological carbon fixation and remineralization. Carbon 167-173 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 26-29 31543487-2 2019 The seasonal variation in sea surface temperature (SST)-normalized fCO2SW in the study area was largely explained by sea surface concentrations of dissolved inorganic carbon modulated by the water column stability in association with biological carbon fixation and remineralization. Carbon 245-251 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 4-7 34592550-2 2022 Different Co2(OH)2CO3 nanostructures including two-dimensional (2D) nanosheets (NSs) and one-dimensional (1D) nanowires (NWs), were synthesized on self-supported carbon cloth substrates by a facile hydrothermal method. Carbon 162-168 complement C2 Homo sapiens 10-13 31543487-2 2019 The seasonal variation in sea surface temperature (SST)-normalized fCO2SW in the study area was largely explained by sea surface concentrations of dissolved inorganic carbon modulated by the water column stability in association with biological carbon fixation and remineralization. Carbon 245-251 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 26-29 31780651-0 2019 Tidal wetland resilience to sea level rise increases their carbon sequestration capacity in United States. Carbon 59-65 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 28-31 34953211-5 2022 Following 4-week injections of poly I:C, not only hepatic RIG-I, but also TLR3 and MDA5 showed female-predominance. Carbon 38-39 toll-like receptor 3 Mus musculus 74-78 31624147-5 2019 The resulting interface involved the Galpha alpha5-helix bound to the concave surface of Ric8A and the Galpha beta-sheet that wraps around the C-terminal part of the Ric8A armadillo domain, leading to a severe disruption of the GDP-binding site. Carbon 143-144 succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens 37-43 34755655-10 2022 However, EPA was found to reduce the C-C motif ligands 4 (CCL4) level (p < 0.001). Carbon 37-38 C-C motif chemokine ligand 4 Homo sapiens 58-62 31624147-5 2019 The resulting interface involved the Galpha alpha5-helix bound to the concave surface of Ric8A and the Galpha beta-sheet that wraps around the C-terminal part of the Ric8A armadillo domain, leading to a severe disruption of the GDP-binding site. Carbon 143-144 succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens 103-109 31624147-6 2019 Further modeling of the flexible C-terminal tail of Ric8A indicated that it interacts with the effector surface of Galpha. Carbon 33-34 succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens 115-121 34785778-0 2022 Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance. Carbon 53-59 N-alpha-acetyltransferase 40, NatD catalytic subunit Homo sapiens 37-42 34785778-4 2022 Here, using transcriptomic followed by metabolomic analysis in colorectal cancer (CRC) cells, we demonstrate that NAA40 controls key one-carbon metabolic genes and corresponding metabolites. Carbon 137-143 N-alpha-acetyltransferase 40, NatD catalytic subunit Homo sapiens 114-119 34785778-7 2022 Specifically, NAA40 stimulates transcription of the one-carbon metabolic gene thymidylate synthase (TYMS), whose product is targeted by 5-fluorouracil (5-FU) and accordingly in primary CRC tumours NAA40 expression associates with TYMS levels and poorer 5-FU response. Carbon 56-62 N-alpha-acetyltransferase 40, NatD catalytic subunit Homo sapiens 14-19 34785778-7 2022 Specifically, NAA40 stimulates transcription of the one-carbon metabolic gene thymidylate synthase (TYMS), whose product is targeted by 5-fluorouracil (5-FU) and accordingly in primary CRC tumours NAA40 expression associates with TYMS levels and poorer 5-FU response. Carbon 56-62 thymidylate synthetase Homo sapiens 78-98 34785778-7 2022 Specifically, NAA40 stimulates transcription of the one-carbon metabolic gene thymidylate synthase (TYMS), whose product is targeted by 5-fluorouracil (5-FU) and accordingly in primary CRC tumours NAA40 expression associates with TYMS levels and poorer 5-FU response. Carbon 56-62 thymidylate synthetase Homo sapiens 100-104 31690658-6 2019 Second, Pat1 directly activates decapping by binding elements in the disordered C-terminal extension of Dcp2, alleviating autoinhibition and promoting substrate binding. Carbon 80-81 amyloid beta precursor protein binding protein 2 Homo sapiens 8-12 34870367-1 2022 3D ZIF-67-particles-impregnated cellulose-nanofiber nanosheets with oriented macropores are synthesized via directional-freezing-assisted in situ self-assembly, and converted to 3D CoP-nanoparticle (NP)-embedded hierarchical, but macropores-oriented, N-doped carbon nanosheets via calcination and phosphidation. Carbon 259-265 caspase recruitment domain family member 16 Homo sapiens 181-184 34870367-5 2022 The outstanding catalytic activity is ascribed to the uniformly-dispersed small CoP NPs in the 3D carbon sheets and the hierarchical nanostructure with rich oriented pores. Carbon 98-104 caspase recruitment domain family member 16 Homo sapiens 80-83 12491770-2 2002 Troponin is a Ca2+ receptive protein consisting of three differet components, troponins C, I, and T. The essential mechanisms of Ca(2+)-regulation are the inhibition of contractile interaction between myosin and actin by the inhibitory action of troponin I and the reversal of the inhibition by troponin I through the Ca(2+)-binding to troponin C. Carbon 14-15 myosin heavy chain 14 Homo sapiens 201-207 31734752-1 2019 A glassy carbon electrode (GCE) was modified with nitrogen-enriched carbon frameworks decorated with palladium nanoparticles (Pd@NCF/GCEs). Carbon 68-74 neutrophil cytosolic factor 4 Homo sapiens 129-132 12420140-6 2002 HAP2 is required to sporulate in any carbon source, whereas GRR1 is required for glucose repression of sporulation. Carbon 37-43 transcription activator HAP2 Saccharomyces cerevisiae S288C 0-4 34914376-0 2021 Interfacial Ammonia Selectivity, Atmospheric Passivation, and Molecular Identification in Graphene-Nanopored Activated Carbon Molecular-Sieve Gas Sensors. Carbon 119-125 gastrin Homo sapiens 142-145 34914376-3 2021 Herein, target gas sensing at the graphene-activated carbon interface of a graphene-nanopored activated carbon molecular-sieve sensor obtained via the postlithographic pyrolysis of Novolac resin residues on graphene nanoribbons is shown to simultaneously induce ammonia selectivity and atmospheric passivation of graphene. Carbon 53-59 gastrin Homo sapiens 15-18 34914376-3 2021 Herein, target gas sensing at the graphene-activated carbon interface of a graphene-nanopored activated carbon molecular-sieve sensor obtained via the postlithographic pyrolysis of Novolac resin residues on graphene nanoribbons is shown to simultaneously induce ammonia selectivity and atmospheric passivation of graphene. Carbon 104-110 gastrin Homo sapiens 15-18 31717598-4 2019 Nano-copper was deposited onto the surface of carbon fiber to enhance the current concentration and mass transfer rate of Cd2+ during measurement, which improved the electrochemical detection sensitivity significantly (by up to 3.7 x 108 nA/nM) and broadened the linear range to 10~105 nM. Carbon 46-52 CD2 molecule Homo sapiens 122-125 34946687-10 2021 Four MET degradation products were identified by untargeted analysis, formed by the rearrangement of the metronidazole and the C-C bond breaking. Carbon 127-128 SAFB like transcription modulator Homo sapiens 5-8 34946687-10 2021 Four MET degradation products were identified by untargeted analysis, formed by the rearrangement of the metronidazole and the C-C bond breaking. Carbon 129-130 SAFB like transcription modulator Homo sapiens 5-8 12197721-3 2002 Both isomers undergo rearrangement with intramolecular chelation of the carbonyl oxygen at a boron site, thereby opening the cluster and generating arachno-2,3,-mu(C)-5-eta1(O)-Me{C(O)OMe}C-1,2-(Cp*Ru)2B3H7. Carbon 164-165 secreted phosphoprotein 1 Homo sapiens 169-173 31763525-6 2019 It was observed that it was necessary to include the effect of ash on the variations of char structures during the char gasification to get an accurate description of reaction rate versus carbon conversion throughout the gasification of the tri-high coal chars. Carbon 188-194 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 241-244 12164222-3 2002 The pharmacophore Ph1 consists of two oxygen atoms and four carbon atoms. Carbon 60-66 alanine--glyoxylate and serine--pyruvate aminotransferase Homo sapiens 18-21 34699116-4 2021 Compared to individual Co-B and NiWO4 , it also shows enhanced rate capability Besides, NiWO4 /Co-B/activated carbon supercapacitor device can provide a good specific capacitance and a maximum energy density of 10.92 Wh kg-1 at 200 W kg-1 . Carbon 110-116 metabolism of cobalamin associated B Homo sapiens 23-27 31689974-0 2019 Gas Biosensor Arrays Based on Single-Stranded DNA-Functionalized Single-Walled Carbon Nanotubes for the Detection of Volatile Organic Compound Biomarkers Released by Huanglongbing Disease-Infected Citrus Trees. Carbon 79-85 gastrin Homo sapiens 0-3 34699116-4 2021 Compared to individual Co-B and NiWO4 , it also shows enhanced rate capability Besides, NiWO4 /Co-B/activated carbon supercapacitor device can provide a good specific capacitance and a maximum energy density of 10.92 Wh kg-1 at 200 W kg-1 . Carbon 110-116 metabolism of cobalamin associated B Homo sapiens 95-99 12061888-3 2002 Compounds with short (<5 carbons) hydrocarbon chains at both C-2 and C-3 were generally inactive. Carbon 28-35 complement C2 Homo sapiens 64-75 31839814-20 2019 KEGG analysis of selective gene sets shows that downregulated DEGs significantly enriched for processes related to carbon metabolism, Rap1 signaling pathway. Carbon 115-121 RAP1A, member of RAS oncogene family Homo sapiens 134-138 12054929-2 2002 Among all the oxygenated carbons of the substrate, C-1, -4, -5, and -6 are directly involved in the chemical transformation. Carbon 25-32 heterogeneous nuclear ribonucleoprotein C Homo sapiens 51-70 34882718-5 2021 We further demonstrated that activation of TLR3 (mediated by eRNA) by AH exposure in mice induced cTrop-T release and Poly I:C (TLR3 agonist) also induced cTrop-T release, but the pre-treatment of TLR3 immuno-neutralizing antibody or silencing of Tlr3 gene or RNaseA treatment two hrs before AH exposure, significantly abrogated AH-induced Caspase 3 activity as well as cTrop-T release. Carbon 125-126 toll-like receptor 3 Mus musculus 43-47 34882718-5 2021 We further demonstrated that activation of TLR3 (mediated by eRNA) by AH exposure in mice induced cTrop-T release and Poly I:C (TLR3 agonist) also induced cTrop-T release, but the pre-treatment of TLR3 immuno-neutralizing antibody or silencing of Tlr3 gene or RNaseA treatment two hrs before AH exposure, significantly abrogated AH-induced Caspase 3 activity as well as cTrop-T release. Carbon 125-126 toll-like receptor 3 Mus musculus 128-132 31672640-2 2019 Alternative mRNA splicing at sites named y and z in the C-terminal part of agrin regulates its interaction with a receptor complex consisting of the agrin-binding protein low-density lipoprotein receptor-related protein 4 (Lrp4) and the tyrosine kinase muscle specific kinase (MuSK). Carbon 56-57 muscle associated receptor tyrosine kinase Homo sapiens 277-281 34806099-8 2021 The air- and moisture-stable LPd(py) complexes were successfully employed as catalysts in two types of C-C coupling reactions. Carbon 103-104 acyl-CoA synthetase bubblegum family member 1 Homo sapiens 29-32 34806099-8 2021 The air- and moisture-stable LPd(py) complexes were successfully employed as catalysts in two types of C-C coupling reactions. Carbon 105-106 acyl-CoA synthetase bubblegum family member 1 Homo sapiens 29-32 31727786-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2, and EXO70F1. Carbon 22-23 RPM1 interacting protein 4 Arabidopsis thaliana 47-53 34947099-0 2021 Low-Carbon and Fundamental Properties of Eco-Efficient Mortar with Recycled Powders. Carbon 4-10 ciliogenesis associated kinase 1 Homo sapiens 41-44 34963966-0 2021 Experimental Analysis and Numerical Simulation of the Stability of Geological Storage of CO2: A Case Study of Transforming a Depleted Gas Reservoir into a Carbon Sink Carrier. Carbon 155-161 gastrin Homo sapiens 134-137 11988075-0 2002 The same rat Delta6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis. Carbon 67-73 fatty acid desaturase 2 Rattus norvegicus 19-30 11988075-8 2002 Evidence is therefore presented that the same rat Delta6-desaturase catalyses not only the conversion of C(18:3) n-3 to C(18:4) n-3, but also the conversion of C(24:5) n-3 to C(24:6) n-3. Carbon 105-106 fatty acid desaturase 2 Rattus norvegicus 56-67 11988075-8 2002 Evidence is therefore presented that the same rat Delta6-desaturase catalyses not only the conversion of C(18:3) n-3 to C(18:4) n-3, but also the conversion of C(24:5) n-3 to C(24:6) n-3. Carbon 120-121 fatty acid desaturase 2 Rattus norvegicus 56-67 11988075-8 2002 Evidence is therefore presented that the same rat Delta6-desaturase catalyses not only the conversion of C(18:3) n-3 to C(18:4) n-3, but also the conversion of C(24:5) n-3 to C(24:6) n-3. Carbon 120-121 fatty acid desaturase 2 Rattus norvegicus 56-67 11988075-8 2002 Evidence is therefore presented that the same rat Delta6-desaturase catalyses not only the conversion of C(18:3) n-3 to C(18:4) n-3, but also the conversion of C(24:5) n-3 to C(24:6) n-3. Carbon 120-121 fatty acid desaturase 2 Rattus norvegicus 56-67 31727786-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2, and EXO70F1. Carbon 22-23 exocyst subunit exo70 family protein B1 Arabidopsis thaliana 90-97 34719883-4 2021 Herein, a series of lanthanide-doped blue-, green-, and red-fluorescent carbon nanodots (namely, B-Cdots(Ln1 ), G-Cdots(Ln2 ), and R-Cdots(Ln3 )) as fluorescence and mass dual-modal tags are developed. Carbon 72-78 phytanoyl-CoA 2-hydroxylase Homo sapiens 105-108 31727786-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2, and EXO70F1. Carbon 22-23 exocyst subunit exo70 family protein E2 Arabidopsis thaliana 108-115 31398779-3 2019 This study based on molecular biological methods (qPCR, Illumina MiSeq sequencing technique) to investigate the effect of Fe(II) and environmental factors on cbbM genes containing carbon fixing microbes. Carbon 180-186 opsin 1, medium wave sensitive Homo sapiens 158-162 34500138-1 2021 Methylene blue (MB) adsorption onto a two-dimensional molybdenum disulfide (2D MoS2)/graphene oxide (GO) nanocomposite sitting on a screen-printed carbon electrode (SPCE) is used to develop a new sensitive label-free electrochemical immunosensor for the detection of matrix metalloproteinase-7 (MMP-7) cancer biomarkers. Carbon 147-153 matrix metallopeptidase 7 Homo sapiens 267-293 34500138-1 2021 Methylene blue (MB) adsorption onto a two-dimensional molybdenum disulfide (2D MoS2)/graphene oxide (GO) nanocomposite sitting on a screen-printed carbon electrode (SPCE) is used to develop a new sensitive label-free electrochemical immunosensor for the detection of matrix metalloproteinase-7 (MMP-7) cancer biomarkers. Carbon 147-153 matrix metallopeptidase 7 Homo sapiens 295-300 31634379-5 2019 In the comparison of phytoplankton grown at 1 and 4 C the rGP/R decreased from 11.5 to 7.7 in Chaetoceros sp., from 9.1 to 3.2 in Phaeocystis antarctica strain 109, and from 12.4 to 7.0 in P. antarctica strain 764, respectively. Carbon 52-53 G protein-coupled receptor 176 Rattus norvegicus 58-63 31634379-7 2019 Moreover, the different rGP/R at 1 and 4 C were caused by changes of temperature-dependent respiration rates but were independent of changes of photosynthetic rates. Carbon 41-42 G protein-coupled receptor 176 Rattus norvegicus 24-29 31444200-9 2019 These findings suggest that past HF activity in streams can affect the microbial community response to environmental perturbation such as that caused by the biocide DBNPA.IMPORTANCE Unconventional oil and gas activity can affect pH, total organic carbon, and microbial communities in surface water, altering their ability to respond to new environmental and/or anthropogenic perturbations. Carbon 247-253 gastrin Homo sapiens 205-208 31559991-0 2019 A pyrolysis-phosphorization approach to fabricate carbon nanotubes with embedded CoP nanoparticles for ambient electrosynthesis of ammonia. Carbon 50-56 caspase recruitment domain family member 16 Homo sapiens 81-84 31559991-1 2019 We report a pyrolysis-phosphorization approach to fabricate carbon nanotubes with embedded CoP nanoparticles (CoP/CNs) using ZIF-67 as a precursor for electrocatalytic nitrogen (N2) reduction to ammonia (NH3) under ambient conditions. Carbon 60-66 caspase recruitment domain family member 16 Homo sapiens 91-94 31559991-1 2019 We report a pyrolysis-phosphorization approach to fabricate carbon nanotubes with embedded CoP nanoparticles (CoP/CNs) using ZIF-67 as a precursor for electrocatalytic nitrogen (N2) reduction to ammonia (NH3) under ambient conditions. Carbon 60-66 caspase recruitment domain family member 16 Homo sapiens 110-113 31535845-5 2019 Benefiting from the synergistic coupling effect of CoP and MoS2 and the nitrogen doped carbon matrix, advanced HER both in acid and alkaline solution as well as splendid OER performance in alkaline aqueous were achieved. Carbon 87-93 caspase recruitment domain family member 16 Homo sapiens 51-54 31538763-2 2019 Herein, an SnSe/FLG (few-layer graphene) composite with high tap density (2.3 g cm-3) is synthesized via plasma milling method, in which SnSe nanoparticles are strongly bound with the FLG matrix, owing to both Sn-C and Se-C bonds, to form nanosized primary particles and then assemble to microsized secondary granules. Carbon 213-214 filaggrin Homo sapiens 16-19 31538763-2 2019 Herein, an SnSe/FLG (few-layer graphene) composite with high tap density (2.3 g cm-3) is synthesized via plasma milling method, in which SnSe nanoparticles are strongly bound with the FLG matrix, owing to both Sn-C and Se-C bonds, to form nanosized primary particles and then assemble to microsized secondary granules. Carbon 213-214 filaggrin Homo sapiens 184-187 31564495-9 2019 We further demonstrate that the N terminus (including a YISY motif) of the RALF4 peptide ligand interacts strongly with BUPS-ANX receptors but weakly with LLGs and is essential for its biological function, and its C-terminal region is sufficient for LLG binding. Carbon 214-215 ralf-like 4 Arabidopsis thaliana 75-80 31468706-4 2019 Extracellular flux analysis and carbon tracing experiments (U-13 C-glucose and U-13 C-glutamine) reveal that within 5 h, activation of LXRbeta results in reprogramming of tumor cell metabolism, leading to suppression of mitochondrial respiration, a phenomenon not observed in normal human astrocytes. Carbon 32-38 nuclear receptor subfamily 1 group H member 2 Homo sapiens 135-142 31448908-3 2019 The furnace with the existing low-NOx combustion art showed NOx emissions of about 900 mg/m3 at 6% O2 and carbon in fly ash of about 5%. Carbon 106-112 NADPH oxidase Drosophila melanogaster 34-37 31548691-3 2019 Using structural and biochemical studies, along with reassessment of previous cryo-electron microscopy structures, we find that the C-terminal cholesterol attached to Sonic hedgehog (Shh) binds the first extracellular domain of PTCH1 and promotes its inactivation, thus triggering HH signaling. Carbon 132-133 sonic hedgehog signaling molecule Homo sapiens 167-181 31548691-3 2019 Using structural and biochemical studies, along with reassessment of previous cryo-electron microscopy structures, we find that the C-terminal cholesterol attached to Sonic hedgehog (Shh) binds the first extracellular domain of PTCH1 and promotes its inactivation, thus triggering HH signaling. Carbon 132-133 sonic hedgehog signaling molecule Homo sapiens 183-186 31548691-5 2019 Thus, Shh inactivates PTCH1 by grasping its extracellular domain with two lipidic pincers, the N-terminal palmitate and the C-terminal cholesterol, which are both inserted into the PTCH1 protein core. Carbon 24-25 sonic hedgehog signaling molecule Homo sapiens 6-9 31700225-0 2019 Autosomal dominant nanophthalmos and high hyperopia associated with a C-terminal frameshift variant in MYRF. Carbon 70-71 myelin regulatory factor Homo sapiens 103-107 31700225-8 2019 Conclusions: C-terminal variants in MYRF, which are expected to escape nonsense-mediated decay, represent a rare cause of autosomal dominant nanophthalmos with or without dextrocardia or congenital diaphragmatic hernia. Carbon 0-1 myelin regulatory factor Homo sapiens 36-40 31607862-6 2019 Using previously reported RNA-sequencing analyses, we identified an unexpected increase in Shank3 transcripts in two different Shank3 mutant mouse lines (Shank3B and Shank3DeltaC) having partial deletions of Shank3 exons. Carbon 177-178 SH3 and multiple ankyrin repeat domains 3 Mus musculus 91-97 31383588-1 2019 Inspired by the cytotoxicity of perphenazine toward cancer cells and its ability to activate the serine/threonine protein phosphatase 2A (PP2A), we prepared series of ether-carbon linked analogs of a constrained synthetic sphingolipid analog 3, known for its cytotoxicity, nutrient transporter down-regulation and vacuolation properties, incorporating the tricyclic neuroleptics phenoxazine and phenothiazine to represent hybrid structures with possible synergistic cytotoxic activity. Carbon 173-179 protein phosphatase 2 phosphatase activator Homo sapiens 138-142 31238222-3 2019 In this study, granular activated carbon (GAC) was incorporated into a bioreactor fed with raw incineration leachate. Carbon 34-40 glutaminase Homo sapiens 42-45 34666994-4 2021 The characteristic nature of carbon-bound exogenous compound had a strong association with patient outcome, tumor progression, the tumor immune microenvironment, PD-L1 expression, and DNA damage. Carbon 29-35 CD274 molecule Homo sapiens 162-167 34186386-2 2021 To tackle these challenges, the amorphous CoP anchored on N-doped carbon nanospheres with hollow porous structures (CoP/HCS) has been synthesized as a superior sulfur host via a facial pyrolysis approach. Carbon 66-72 caspase recruitment domain family member 16 Homo sapiens 116-119 34186386-5 2021 More importantly, the synergistic incorporation of CoP and HCS improved the inherit low conductivity by anchoring on the N-doped carbon hollow, thus leading to excellent performance for Li-S batteries. Carbon 129-135 caspase recruitment domain family member 16 Homo sapiens 51-54 34695651-5 2021 PU.1 expression also primes the cells to develop a strong immune response against the dsRNA virus mimic polyinosinic:polycytidylic acid (poly I:C) by significantly up-regulating Interferon-beta (14.9 fold change with p-value <0.0001). Carbon 144-145 Spi-1 proto-oncogene Homo sapiens 0-4 34845636-5 2022 The findings showed that rent on mineral resources, oil resources, and forest rent have a positive and significant impact on carbon emissions in G-20 countries. Carbon 125-131 chromosome 3 open reading frame 18 Homo sapiens 145-149 34946051-2 2021 lactis CRL 581 beneficially modulates the intestinal antiviral innate immune response triggered by the Toll-like receptor 3 (TLR3) agonist poly(I:C) in vivo. Carbon 146-148 toll-like receptor 3 Mus musculus 125-129 34899719-9 2021 Treatment with IC87114 or transfection with siRNA targeting PI3K p110delta enhanced poly I:C-induced gene and protein expression of PD-L2, whereas IC87114 suppressed poly I:C-induced PD-L1. Carbon 91-92 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Homo sapiens 65-74 34899719-11 2021 Transfection with siIRF3 counteracted the enhancement of poly I:C-induced PD-L2 by IC87114, whereas IC87114 suppressed poly I:C-induced PD-L1 regardless of transfection with siNC or siIRF3. Carbon 126-127 CD274 molecule Homo sapiens 136-141 34609963-6 2021 PGC-1alpha re-expression in RCC cells restores the expression of TCA cycle enzymes in vitro and in vivo and leads to enhanced glucose carbon incorporation into TCA cycle intermediates. Carbon 134-140 PPARG coactivator 1 alpha Sus scrofa 0-10 34426217-3 2021 This environmental concern, which entails all economic agents" responsibility, has not gone unnoticed, so in 2015 the Paris Climate Conference (COP: 21) was held, whose main objective is to reduce carbon emissions on the planet. Carbon 197-203 caspase recruitment domain family member 16 Homo sapiens 144-147 34643326-2 2021 Herein, a hierarchical framework consisting of core-shell structured carbon nanotubes@K-birnessite-MnO2 enwrapped by graphene/carbon black bicomponent networks (CNT@KMO@GC) via a simple method for ZIBs is designed and developed. Carbon 69-75 kynurenine 3-monooxygenase Homo sapiens 165-168 34643326-2 2021 Herein, a hierarchical framework consisting of core-shell structured carbon nanotubes@K-birnessite-MnO2 enwrapped by graphene/carbon black bicomponent networks (CNT@KMO@GC) via a simple method for ZIBs is designed and developed. Carbon 126-132 kynurenine 3-monooxygenase Homo sapiens 165-168 34705862-6 2021 CMPK2 was significantly induced at both RNA and protein levels upon stimulation with TLR4 ligand-LPS and TLR3 ligand-Poly (I:C). Carbon 125-127 cytidine/uridine monophosphate kinase 2 Homo sapiens 0-5 34464868-7 2021 The up-regulation of CHST3, CHST12, CHST13, and CHST15 was directly correlated with C-4 and C-6 sulfation. Carbon 84-85 carbohydrate sulfotransferase 12 Homo sapiens 28-34 34464868-7 2021 The up-regulation of CHST3, CHST12, CHST13, and CHST15 was directly correlated with C-4 and C-6 sulfation. Carbon 84-85 carbohydrate sulfotransferase 15 Homo sapiens 48-54 34464868-7 2021 The up-regulation of CHST3, CHST12, CHST13, and CHST15 was directly correlated with C-4 and C-6 sulfation. Carbon 92-93 carbohydrate sulfotransferase 15 Homo sapiens 48-54 34770842-5 2021 Therefore, in the current study, HBx to Bcl-xL is abrogated on high-affinity carbon nanotubes using computational structural biology tools. Carbon 77-83 X protein Hepatitis B virus 33-36 34633826-2 2021 Among them, 6-NEt2-CUM reveals prominent excited-state intramolecular charge transfer with a large change of dipole moment (Deltamu ~ 18.23 D), hence displaying remarkable emission solvatochromism from the green (536 nm in cyclohexane) to far-red region (714 nm in dimethyl sulfoxide) and a high-temperature sensitivity (-0.23 nm C-1). Carbon 331-332 tetraspanin 12 Homo sapiens 14-18 34596417-2 2021 We report here the first Lewis acid-catalyzed C-C bond forming reactions of these species with TMSCN and silyl enol ethers as nucleophiles and utilizing TIPSOTf as well as Sc(OTf)3 as catalysts. Carbon 46-47 POU class 5 homeobox 1 Homo sapiens 172-180 34632622-0 2021 An electrochemical aptasensor for detection of prostate-specific antigen using reduced graphene gold nano composite and Cu/ carbon quantum dots. Carbon 124-130 kallikrein related peptidase 3 Homo sapiens 47-72 34626018-3 2021 Different from the previously reported single-atom or dual-atom configurations, a new type of ternary-atom catalyst, which consists of atomically dispersed, nitrogen-coordinated Co-Co dimers, and Fe single sites (i.e., Co2 -N6 and Fe-N4 structures) that are coanchored on highly graphitized carbon supports is developed. Carbon 291-297 complement C2 Homo sapiens 219-222 34760190-4 2021 A formation energy analysis on several NiN x C4-x (x = 1-4) moieties indicates that the predominant Ni moieties of Ni-N-C SACs are expected to have a formula of NiN4. Carbon 120-121 ninein Homo sapiens 39-42 34546700-0 2021 Structural Study of Polyacrylonitrile-Based Carbon Nanofibers for Understanding Gas Adsorption. Carbon 44-50 gastrin Homo sapiens 80-83 34617126-0 2021 Colorimetric immunosensor based on glassy carbon microspheres test strips for the detection of prostate-specific antigen. Carbon 42-48 kallikrein related peptidase 3 Homo sapiens 95-120 34617126-1 2021 Micro-sized glassy carbon microspheres (GCMs, typically 3 mum in diameter) instead of nano-sized gold nanoparticles (AuNPs, typically 20 nm in diameter) were for the first time used as signal markers for the quantitative detection of antigen such as prostate-specific antigen (PSA). Carbon 19-25 kallikrein related peptidase 3 Homo sapiens 250-275 34617126-1 2021 Micro-sized glassy carbon microspheres (GCMs, typically 3 mum in diameter) instead of nano-sized gold nanoparticles (AuNPs, typically 20 nm in diameter) were for the first time used as signal markers for the quantitative detection of antigen such as prostate-specific antigen (PSA). Carbon 19-25 kallikrein related peptidase 3 Homo sapiens 277-280 34139227-7 2021 Log Kd and log soil organic carbon-water distribution coefficient (Koc) both increase with increasing carbon chain length of PFASs. Carbon 28-34 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 67-70 34139227-7 2021 Log Kd and log soil organic carbon-water distribution coefficient (Koc) both increase with increasing carbon chain length of PFASs. Carbon 102-108 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 67-70 34507099-6 2021 The bicyclo(3.3.0)octane scaffold, found in natural products and in anticancer compounds, are expected to keep their activity in PG analogs; the bulky scaffold, separated by a methylene group from the C-15 carbon atom, is expected to diminish the inactivation of the PG analog by enzyme oxidation of 15alpha-OH oxidation to 15-Keto via PGDH pathway. Carbon 206-212 15-hydroxyprostaglandin dehydrogenase Homo sapiens 336-340 34594351-7 2021 These anatomical features, along with a C4-specific carbon fixation enzyme (PEPC), form a CO2-concentration mechanism that ensures a high photosynthetic efficiency. Carbon 52-58 peptidase C Homo sapiens 76-80 34196706-0 2021 High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells. Carbon 28-34 CD274 molecule Homo sapiens 63-68 34196706-3 2021 Here, we examined the impact of high linear energy transfer (LET) carbon-ion irradiation on the expression of PD-L1 in human osteosarcoma U2OS cells. Carbon 66-72 CD274 molecule Homo sapiens 110-115 34196706-4 2021 We found that the upregulation of PD-L1 expression after high LET carbon-ion irradiation was greater than that induced by X-rays at the same physical and relative biological effectiveness (RBE) dose, and that the upregulation of PD-L1 induced by high LET carbon-ion irradiation was predominantly dependent on ataxia telangiectasia and Rad3-related (ATR) kinase activity. Carbon 66-72 CD274 molecule Homo sapiens 34-39 34196706-4 2021 We found that the upregulation of PD-L1 expression after high LET carbon-ion irradiation was greater than that induced by X-rays at the same physical and relative biological effectiveness (RBE) dose, and that the upregulation of PD-L1 induced by high LET carbon-ion irradiation was predominantly dependent on ataxia telangiectasia and Rad3-related (ATR) kinase activity. Carbon 255-261 CD274 molecule Homo sapiens 34-39 34196706-4 2021 We found that the upregulation of PD-L1 expression after high LET carbon-ion irradiation was greater than that induced by X-rays at the same physical and relative biological effectiveness (RBE) dose, and that the upregulation of PD-L1 induced by high LET carbon-ion irradiation was predominantly dependent on ataxia telangiectasia and Rad3-related (ATR) kinase activity. Carbon 255-261 CD274 molecule Homo sapiens 229-234 34196706-7 2021 The three-dimensional structured illumination microscopy (3D-SIM) analyses revealed substantial increases in the number of presented PD-L1 molecules on the cell surface after high LET carbon-ion irradiation compared with X-ray irradiation. Carbon 184-190 CD274 molecule Homo sapiens 133-138 34491425-0 2021 Societal importance of Antarctic negative feedbacks on climate change: blue carbon gains from sea ice, ice shelf and glacier losses. Carbon 76-82 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 94-97 34491425-6 2021 Decreasing sea ice extent drives longer (not necessarily larger biomass) smaller cell-sized phytoplankton blooms, increasing growth of many primary consumers and benthic carbon storage-where sequestration chances are maximal. Carbon 170-176 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 11-14 34568660-0 2021 Effect of Nonwoven Carbon Tissue-Reinforced Epoxy Resin Adhesive Layer on the Single Lap Bonding Strength of Aluminum Alloy Joints. Carbon 19-25 LAP Homo sapiens 85-88 34568660-2 2021 The effect of the nonwoven carbon tissue (NWCT) composite adhesive layer on the bonding strength and reliability of aluminum alloy of single lap joints (SLJ) was investigated by embedding NWCT into the epoxy adhesive layer. Carbon 27-33 LAP Homo sapiens 141-144 34427417-5 2021 Endosomal stimulation of TLR3 by adding poly(I:C) in cell culture media or cytoplasmic stimulation of MDA5 by transfecting poly(I:C) resulted in significant increases of TLR3, MDA5, interferon (IFN) beta, and interleukin 8 gene expression levels in wild type (WT) cells. Carbon 130-132 interferon induced with helicase C domain 1 Homo sapiens 102-106 12065897-6 2002 The cells carrying Hsp60 mutants with an epitope of influenza hemagglutinin (HA) and T7 alone in the C-terminal region grew normally, but the mutant containing both HA and T7 was unable to grow in nonfermentable carbon sources. Carbon 212-218 chaperone ATPase HSP60 Saccharomyces cerevisiae S288C 19-24 11925208-6 2002 Substituents at the carbons adjacent to the allylic carbinol carbon (i.e., C-2 or C-6 in cyclohexenone-derived substrates) directed the stereochemical course of the rearrangement. Carbon 20-27 complement C2 Homo sapiens 75-78 11925208-6 2002 Substituents at the carbons adjacent to the allylic carbinol carbon (i.e., C-2 or C-6 in cyclohexenone-derived substrates) directed the stereochemical course of the rearrangement. Carbon 20-26 complement C2 Homo sapiens 75-78 11916863-4 2002 Our results suggest that in both C2- and C18-Cer, an H-bond network is formed in which the amide proton NH is donated to the OH groups on carbons C1 and C3 of the sphingosine backbone. Carbon 138-145 heterogeneous nuclear ribonucleoprotein C Homo sapiens 146-155 11909695-4 2002 However, when C-12 lies deeper and is hence less available to O(2)(*-), the lactonic carbon C-2, which lies in a shallower region (E(T)(30) = 43-49), is the preferred site for superoxide-mediated cleavage. Carbon 14-15 complement C2 Homo sapiens 92-95 11936179-6 2002 Fitting the depth-dose curve to the calculated SOBP curve also gives biologically equivalent dose distributions in the case of a carbon beam. Carbon 129-135 sine oculis binding protein homolog Homo sapiens 47-51 12014441-3 2002 Feeding experiments with [1-13C]- and [6-13C]-D-glucose revealed that the carbon skeletons of both a glucose residue and a cyclopentane ring moiety in 1 were each derived from glucose, and that C-C bond formation between C-1 and C-5 of glucose occurred during the cyclopentane ring formation. Carbon 74-80 heterogeneous nuclear ribonucleoprotein C Homo sapiens 221-232 11846173-10 2002 Poly I/C suppressed CYP1A1 by 20-25% (n.s.) Carbon 7-8 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 20-26 11754736-2 2002 According to the three-dimensional structure of a porcine kidney D-amino acid oxidase-substrate (D-leucine) complex model, the G313 backbone carbonyl recognizes the substrate amino group by hydrogen bonding and the side-chain hydroxyl of T317 forms a hydrogen bond with C(2)=O of the flavin moiety of FAD [Miura et al. Carbon 270-271 D-amino acid oxidase Homo sapiens 65-85 11984634-0 2002 Longitudinal and vertical trends of bacterial limitation by phosphorus and carbon in the Mediterranean Sea. Carbon 75-81 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 103-106 11984634-4 2002 Organic carbon stimulation of bacterial production was observed at two stations in the Alboran Sea, where the highest bacterial production was recorded (216 and 349 mg C m(-2) d(-1)) and in the Sicily Strait. Carbon 8-14 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 95-98 11810259-2 2002 Under aerobic conditions, the expression of JEN1 is regulated by the carbon source: the gene is repressed by glucose and induced by non-fermentable substrates. Carbon 69-75 Jen1p Saccharomyces cerevisiae S288C 44-48 11675150-7 2001 The estimated relative risk for lung cancer associated to a single mutated allele in CYP1A1, CYP2E1 or GSTM1 was 2.41 for m2, 1.69 for val, 1.16 for C, 0.71 for c2 and 2.46 for GSTM1(-). Carbon 85-86 complement C2 Homo sapiens 161-169 11748728-4 2001 From Northern blot analysis on the members of the HXT family and studies with HXT5 tagged with the green fluorescent protein (GFP), it is evident that HXT5 is transcribed and translated during conditions of relatively slow growth, during growth on non-fermentable carbon sources and in particular during sporulation. Carbon 264-270 hexose transporter HXT5 Saccharomyces cerevisiae S288C 151-155 11748728-5 2001 In wild-type batch cultivations on fermentable carbon sources, Hxt5p is abundant in stationary phase or after depletion of the fermentable carbon source, which seems independent of the carbon source. Carbon 47-53 hexose transporter HXT5 Saccharomyces cerevisiae S288C 63-68 11748728-5 2001 In wild-type batch cultivations on fermentable carbon sources, Hxt5p is abundant in stationary phase or after depletion of the fermentable carbon source, which seems independent of the carbon source. Carbon 139-145 hexose transporter HXT5 Saccharomyces cerevisiae S288C 63-68 11748728-5 2001 In wild-type batch cultivations on fermentable carbon sources, Hxt5p is abundant in stationary phase or after depletion of the fermentable carbon source, which seems independent of the carbon source. Carbon 139-145 hexose transporter HXT5 Saccharomyces cerevisiae S288C 63-68 11604494-8 2001 We found that Delta 1,2 pre-F(1)beta is more dependent upon the Tom70p receptor for import than WT pre-F(1)beta is, resulting in a growth defect on a nonfermentable carbon source at 15 degrees C. Experiments using an in vitro mitochondrial protein import system suggest that Tom70p functions to maintain a precursor containing the Delta 1,2 pre-F(1)beta import signal in an import-competent conformation. Carbon 165-171 protein channel TOM70 Saccharomyces cerevisiae S288C 64-70 11701378-4 2001 A regulatory role in carbon metabolism is likely but might not be restricted to the TPS control of hexokinase activity as documented for yeast. Carbon 21-27 hexokinase Saccharomyces cerevisiae S288C 99-109 11605654-0 2001 Pyrrolo[2,3-d]pyrimidine thymidylate synthase inhibitors: design and synthesis of one-carbon bridge derivatives. Carbon 86-92 thymidylate synthetase Homo sapiens 25-45 11569808-9 2001 In addition, on the basis of the chemical shift of C-1 carbon on the amylose backbone, it is possible that Chiralpak AD"s structure is a helix with a number of fold less than six. Carbon 55-61 heterogeneous nuclear ribonucleoprotein C Homo sapiens 51-54 11516159-1 2001 The role of cytosolic and mitochondrial serine hydroxymethyltransferase in supplying one-carbon groups for purine and thymidylate biosynthesis in MCF-7 cells was investigated by observing folate-mediated one-carbon metabolism of l-[3-(13)C]serine, [2-(13)C]glycine, and [(13)C]formate. Carbon 208-214 serine hydroxymethyltransferase 1 Homo sapiens 12-71 11486018-4 2001 We show that Srb10 is required for phosphorylation of Sip4 during growth in nonfermentable carbon sources and that the catalytic activity of Srb10 stimulates the ability of LexA-Sip4 to activate transcription of a reporter. Carbon 91-97 cyclin-dependent serine/threonine protein kinase SSN3 Saccharomyces cerevisiae S288C 13-18 11486018-7 2001 These findings support the view that the Srb10 kinase not only plays negative roles in transcriptional control but also has broad positive roles during growth in carbon sources other than glucose. Carbon 162-168 cyclin-dependent serine/threonine protein kinase SSN3 Saccharomyces cerevisiae S288C 41-46 11469793-2 2001 Yeast coq4 mutant strains harboring the COQ4 gene on either single- or multicopy plasmids acquired the ability to grow on media containing a nonfermentable carbon source, synthesize Q(6), and respire. Carbon 156-162 ubiquinone biosynthesis protein COQ4 Saccharomyces cerevisiae S288C 6-10 11469793-2 2001 Yeast coq4 mutant strains harboring the COQ4 gene on either single- or multicopy plasmids acquired the ability to grow on media containing a nonfermentable carbon source, synthesize Q(6), and respire. Carbon 156-162 ubiquinone biosynthesis protein COQ4 Saccharomyces cerevisiae S288C 40-44 11549036-1 2001 Two new yeast strains (SPT1 and SPT2) were isolated and immobilized on glassy carbon electrodes to form microbial biosensors for estimation of biochemical oxygen demand (BOD). Carbon 78-84 Hir2p Saccharomyces cerevisiae S288C 23-27 11454337-4 2001 13C NMR studies using D-(1-(13)C)glucose and D-(1-(13)C)galactose with the CaCl(2) system in CD(3)OD revealed that the C-2 epimerization proceeds via stereospecific rearrangement of the carbon skeleton, or 1,2-carbon shift, and ketose formation proceeds partially through an intramolecular hydrogen migration or 1,2-hydride shift and, in part, via an enediol intermediate. Carbon 186-192 complement C2 Homo sapiens 119-122 11454337-4 2001 13C NMR studies using D-(1-(13)C)glucose and D-(1-(13)C)galactose with the CaCl(2) system in CD(3)OD revealed that the C-2 epimerization proceeds via stereospecific rearrangement of the carbon skeleton, or 1,2-carbon shift, and ketose formation proceeds partially through an intramolecular hydrogen migration or 1,2-hydride shift and, in part, via an enediol intermediate. Carbon 210-216 complement C2 Homo sapiens 119-122 11453994-1 2001 Methylobacterium dichloromethanicum DM4 is able to grow with dichloromethane as the sole carbon and energy source by using a dichloromethane dehalogenase/glutathione S-transferase (GST) for the conversion of dichloromethane to formaldehyde. Carbon 89-95 hematopoietic prostaglandin D synthase Rattus norvegicus 154-179 11414039-1 2001 We evaluated a method to determine organic carbon-normalized soil-water partition coefficients (Koc) of 20 PAHs and 12 PCBs by desorption in the presence of a cosolvent (methanol fractions of 0.1-0.9) and at different temperatures (20-80 degrees C). Carbon 43-49 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 96-99 11446692-4 2001 The values of the mean dipole moment derivatives for the sp and sp2 carbon atoms obtained in this work, 0.032 and -0.133 e, respectively, are in good agreement with the CCD(FC)/6-311 + + G(3d,3p), 0.061 and -0.128 e, and MP2(FC)/6-311 + + G(3d,3p), 0.072 and -0.153 e, theoretical results. Carbon 68-74 tryptase pseudogene 1 Homo sapiens 221-224 11348104-2 2001 The results are interpreted in terms of a transition state where the complexed cation (M[n+] subset Lig) assists the departure of the leaving group Ph(2)P(O)O(-) and, at the same time, favors the attack at carbon of the nucleophile I(-) ("push-pull" mechanism). Carbon 206-212 ubiquitin conjugating enzyme E2 K Homo sapiens 100-103 11154690-1 2001 Fumarylacetoacetate hydrolase (FAH) catalyzes the hydrolytic cleavage of a carbon-carbon bond in fumarylacetoacetate to yield fumarate and acetoacetate as the final step of Phe and Tyr degradation. Carbon 75-81 fumarylacetoacetate hydrolase Homo sapiens 0-29 11154690-1 2001 Fumarylacetoacetate hydrolase (FAH) catalyzes the hydrolytic cleavage of a carbon-carbon bond in fumarylacetoacetate to yield fumarate and acetoacetate as the final step of Phe and Tyr degradation. Carbon 75-81 fumarylacetoacetate hydrolase Homo sapiens 31-34 11154690-1 2001 Fumarylacetoacetate hydrolase (FAH) catalyzes the hydrolytic cleavage of a carbon-carbon bond in fumarylacetoacetate to yield fumarate and acetoacetate as the final step of Phe and Tyr degradation. Carbon 82-88 fumarylacetoacetate hydrolase Homo sapiens 0-29 11154690-1 2001 Fumarylacetoacetate hydrolase (FAH) catalyzes the hydrolytic cleavage of a carbon-carbon bond in fumarylacetoacetate to yield fumarate and acetoacetate as the final step of Phe and Tyr degradation. Carbon 82-88 fumarylacetoacetate hydrolase Homo sapiens 31-34 11311123-1 2001 The key glycolytic HXK2 gene, coding for the enzyme hexokinase 2 (Hxk2p), is expressed when cells of the yeast Saccharomyces cerevisiae are grown on a fermentable medium using glucose, fructose or mannose as a carbon source. Carbon 210-216 hexokinase 2 Saccharomyces cerevisiae S288C 19-23 11311123-1 2001 The key glycolytic HXK2 gene, coding for the enzyme hexokinase 2 (Hxk2p), is expressed when cells of the yeast Saccharomyces cerevisiae are grown on a fermentable medium using glucose, fructose or mannose as a carbon source. Carbon 210-216 hexokinase 2 Saccharomyces cerevisiae S288C 52-64 11311123-1 2001 The key glycolytic HXK2 gene, coding for the enzyme hexokinase 2 (Hxk2p), is expressed when cells of the yeast Saccharomyces cerevisiae are grown on a fermentable medium using glucose, fructose or mannose as a carbon source. Carbon 210-216 hexokinase 2 Saccharomyces cerevisiae S288C 66-71 11311123-2 2001 After shifting the cells to a non-fermentable carbon source, the HXK2 gene is repressed and the HXK1 and GLK1 genes are rapidly de-repressed, producing the enzymes hexokinase 1 (Hxk1p) and glucokinase (Glk1p) respectively. Carbon 46-52 hexokinase 2 Saccharomyces cerevisiae S288C 65-69 11311123-2 2001 After shifting the cells to a non-fermentable carbon source, the HXK2 gene is repressed and the HXK1 and GLK1 genes are rapidly de-repressed, producing the enzymes hexokinase 1 (Hxk1p) and glucokinase (Glk1p) respectively. Carbon 46-52 hexokinase 1 Saccharomyces cerevisiae S288C 164-176 34427417-5 2021 Endosomal stimulation of TLR3 by adding poly(I:C) in cell culture media or cytoplasmic stimulation of MDA5 by transfecting poly(I:C) resulted in significant increases of TLR3, MDA5, interferon (IFN) beta, and interleukin 8 gene expression levels in wild type (WT) cells. Carbon 130-132 interferon induced with helicase C domain 1 Homo sapiens 176-180 34577697-0 2021 PEI-Functionalized Carbon Nanotube Thin Film Sensor for CO2 Gas Detection at Room Temperature. Carbon 19-25 gastrin Homo sapiens 60-63 34169949-7 2021 Based on the analysis of Gene Ontology (GO), STRING and KEGG databases, MFG-E8 relieves oxidative stress induced-L6 cell damage by regulating the expression of these differential proteins mainly via carbon metabolism, glutathione metabolism and mitochondria-mediated metabolic pathways, e.g. carbohydrate, lipid and amino acid metabolism. Carbon 199-205 milk fat globule EGF and factor V/VIII domain containing Rattus norvegicus 72-78 34098313-0 2021 Viral mimetic poly(I:C) induces neutrophil extracellular traps via PAD4 to promote inflammation and thrombosis. Carbon 21-23 peptidyl arginine deiminase 4 Homo sapiens 67-71 31572867-1 2019 In this paper, a hydroxyapatite (HAp)-doped carbon nanofiber (CNF)-modified carbon ionic liquid electrode (CILE) was prepared and used for the investigation on the direct electrochemistry and electrocatalysis of myoglobin (Mb). Carbon 44-50 myoglobin Homo sapiens 212-221 34357468-7 2021 Compared to that of non-porous carbon supported copper nanoparticles (Cu NP/C), this can be reasonable by the improved mass transfer and strengthened synergistic effect between copper nanoparticles and porous carbon substrates. Carbon 31-37 NPC intracellular cholesterol transporter 1 Homo sapiens 73-77 34357468-7 2021 Compared to that of non-porous carbon supported copper nanoparticles (Cu NP/C), this can be reasonable by the improved mass transfer and strengthened synergistic effect between copper nanoparticles and porous carbon substrates. Carbon 209-215 NPC intracellular cholesterol transporter 1 Homo sapiens 73-77 11393227-1 2001 An 1-(pyridylazo)-2-naphthol modified glassy carbon electrode has been investigated as sensor for the measurement of trace levels of Cd2+. Carbon 45-51 CD2 molecule Homo sapiens 133-136 11393227-2 2001 Cd2+ is deposited on the surface of a PAN modified glassy carbon electrode at -1.10 V (vs. SCE) via forming Cd2+-PAN and subsequent reduction at the electrode. Carbon 58-64 CD2 molecule Homo sapiens 0-3 11393227-2 2001 Cd2+ is deposited on the surface of a PAN modified glassy carbon electrode at -1.10 V (vs. SCE) via forming Cd2+-PAN and subsequent reduction at the electrode. Carbon 58-64 CD2 molecule Homo sapiens 108-111 31572867-1 2019 In this paper, a hydroxyapatite (HAp)-doped carbon nanofiber (CNF)-modified carbon ionic liquid electrode (CILE) was prepared and used for the investigation on the direct electrochemistry and electrocatalysis of myoglobin (Mb). Carbon 76-82 myoglobin Homo sapiens 212-221 11430749-1 2001 The mobility of betaCH2 moieties in oxidized and reduced cytochrome b5 was studied by analyzing the 13C relaxation of the J-split components, in terms of C-H dipole-C-H dipole cross correlation rates. Carbon 20-21 cytochrome b5 type A Homo sapiens 57-70 11430749-1 2001 The mobility of betaCH2 moieties in oxidized and reduced cytochrome b5 was studied by analyzing the 13C relaxation of the J-split components, in terms of C-H dipole-C-H dipole cross correlation rates. Carbon 102-103 cytochrome b5 type A Homo sapiens 57-70 34413772-5 2021 The Peyer"s patches lymphocytes isolated from BALB/c mice were stimulated with concanavalin A, or, to mimic viral infection, with a combination of concanavalin A and TLR3 ligand poly I:C. Carbon 185-186 toll-like receptor 3 Mus musculus 166-170 33448841-3 2019 The SFN-CDs are formed by grafting sulforaphane on the amino-rich yellow fluorescent carbon dots, which have excellent optical stability and can be distinguished from normal cells for targeted imaging of cancer cells. Carbon 85-91 RNA exonuclease 2 Homo sapiens 4-7 34153952-0 2021 Water calorimetry-basedkQfactors for Farmer-type ionization chambers in the SOBP of a carbon-ion beam. Carbon 86-92 sine oculis binding protein homolog Homo sapiens 76-80 34132720-4 2021 The electrocatalytic behaviors of carbon paste electrodes modified by complexes 1 and 2 (1-CPE and 2-CPE) were investigated. Carbon 34-40 carboxypeptidase E Homo sapiens 91-94 34132720-4 2021 The electrocatalytic behaviors of carbon paste electrodes modified by complexes 1 and 2 (1-CPE and 2-CPE) were investigated. Carbon 34-40 carboxypeptidase E Homo sapiens 101-104 11349908-3 2001 The carbon-attached HOOH-CO complex is the lower-energy form, and it has an interaction energy of -9.0 kJmol(-1) at the CCSD(T)/6-311++G(3df,3pd)// MP2/6-311++G(3df,3pd) level. Carbon 4-10 tryptase pseudogene 1 Homo sapiens 148-151 31437603-6 2019 The DP operation in clinical like conditions has been tested with the proton and carbon ions beams of Trento proton-therapy center and of the CNAO facility. Carbon 81-87 SRP receptor subunit alpha Homo sapiens 4-6 34356690-0 2021 The Scavenging Effect of Myoglobin from Meat Extracts toward Peroxynitrite Studied with a Flow Injection System Based on Electrochemical Reduction over a Screen-Printed Carbon Electrode Modified with Cobalt Phthalocyanine: Quantification and Kinetics. Carbon 169-175 myoglobin Homo sapiens 25-34 34356690-1 2021 The scavenging activity of myoglobin toward peroxynitrite (PON) was studied in meat extracts, using a new developed electrochemical method (based on cobalt phthalocyanine-modified screen-printed carbon electrode, SPCE/CoPc) and calculating kinetic parameters of PON decay (such as half-time and apparent rate constants). Carbon 195-201 myoglobin Homo sapiens 27-36 34081901-4 2021 Analysis of mouse and human AML models demonstrate that ATF3 directly activates the transcription of genes encoding key enzymatic regulators of serine synthesis, one-carbon metabolism, and de novo purine and pyrimidine synthesis. Carbon 166-172 activating transcription factor 3 Homo sapiens 56-60 11282609-8 2001 The results suggest a redirection of carbon flux in the hxk2 mutant to the production of biomass as a consequence of reduced glucose repression. Carbon 37-43 hexokinase 2 Saccharomyces cerevisiae S288C 56-60 31062431-9 2019 Plants with T-DNA disruptions in RBL10 have greatly decreased 16:3 (acyl carbons:double bonds) and increased 18:3 acyl chain abundance in MGDG of leaves. Carbon 73-80 RHOMBOID-like protein 10 Arabidopsis thaliana 33-38 11963845-4 2001 The modifications are based on cloning the G6PD sequence under the control of promoters that are upregulated by the carbon source used for yeast growth. Carbon 116-122 glucose-6-phosphate dehydrogenase Saccharomyces cerevisiae S288C 43-47 34081901-5 2021 Total steady-state polar metabolite and heavy isotope tracing analyses show that ATF3 inhibition reduces de novo serine synthesis, impedes the incorporation of serine-derived carbons into newly synthesized purines, and disrupts pyrimidine metabolism. Carbon 175-182 activating transcription factor 3 Homo sapiens 81-85 34201568-0 2021 Biomass Related Highly Porous Metal Free Carbon for Gas Storage and Electrocatalytic Applications. Carbon 41-47 gastrin Homo sapiens 52-55 31171181-1 2019 A novel sensor based on carbon supported BiSn alloy nanoparticles (BiSn@C) was prepared for the sensitive detection of Cd2+. Carbon 24-30 CD2 molecule Homo sapiens 119-122 31171181-2 2019 The BiSn@C and Nafion modified glassy carbon electrode (GCE) exhibited improved electrochemical performance in Cd2+ detection, because of its large specific surface area, abundance of active sites, good electrical conductivity, and strong cation exchange ability. Carbon 38-44 CD2 molecule Homo sapiens 111-114 34087175-1 2021 We talk to Alice Clare Newman, new mother, postdoc, and first author of "Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells," about her paper, juggling family and career, and life-changing moments that led to the realization that life doesn"t wait for science. Carbon 144-150 indoleamine 2,3-dioxygenase 1 Homo sapiens 90-94 11165879-6 2001 The Trx-linked peroxidase activity of HSA sharply increased with elongation in the carbon chain of the acyl moiety of acyl-CoA, showing an optimum activity in the presence of palmitoyl-CoA. Carbon 83-89 thioredoxin Homo sapiens 4-7 11169757-0 2001 Cat8 and Sip4 mediate regulated transcriptional activation of the yeast malate dehydrogenase gene MDH2 by three carbon source-responsive promoter elements. Carbon 112-118 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 0-4 31171181-4 2019 The Nafion/BiSn@C/GCE was successfully applied for determination for trace Cd2+ in river samples with satisfying recoveries using the standard addition method. Carbon 16-17 CD2 molecule Homo sapiens 75-78 11169757-0 2001 Cat8 and Sip4 mediate regulated transcriptional activation of the yeast malate dehydrogenase gene MDH2 by three carbon source-responsive promoter elements. Carbon 112-118 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 98-102 11169757-3 2001 We demonstrate the importance of transcriptional activators Hap4, Cat8 and Pip2 for the carbon source-dependent regulation of MDH1, MDH2 and MDH3, respectively. Carbon 88-94 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 66-70 31343153-3 2019 Herein, by employing a combination of the potentiodynamic mode of electrodeposition and low-temperature phosphidation, three-dimensional (3D) holey CoP ultrathin nanosheets are fabricated on a carbon cloth (PD-CoP UNSs/CC) as bifunctional catalysts. Carbon 193-199 caspase recruitment domain family member 16 Homo sapiens 148-151 11169757-3 2001 We demonstrate the importance of transcriptional activators Hap4, Cat8 and Pip2 for the carbon source-dependent regulation of MDH1, MDH2 and MDH3, respectively. Carbon 88-94 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 132-136 11169757-4 2001 The control region of the MDH2 gene required for gluconeogenic growth with C(2) substrates contains three sequence elements similar to the previously identified carbon source-responsive element (CSRE). Carbon 161-167 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 26-30 11113186-4 2001 The tsc13 mutant accumulates high levels of long-chain bases as well as ceramides that harbor fatty acids with chain lengths shorter than 26 carbons. Carbon 141-148 trans-2-enoyl-CoA reductase (NADPH) TSC13 Saccharomyces cerevisiae S288C 4-9 34136101-1 2021 Human serine hydroxymethyltransferase (SHMT) regulates the serine-glycine one carbon metabolism and plays a role in cancer metabolic reprogramming. Carbon 78-84 serine hydroxymethyltransferase 1 Homo sapiens 6-37 34136101-1 2021 Human serine hydroxymethyltransferase (SHMT) regulates the serine-glycine one carbon metabolism and plays a role in cancer metabolic reprogramming. Carbon 78-84 serine hydroxymethyltransferase 1 Homo sapiens 39-43 31125873-7 2019 Results inform cost-benefit analyses for dredging projects and contribute to estimates of the indirect costs to society from carbon emissions through sea-level rise. Carbon 125-131 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 150-153 34121846-1 2021 The new benzimidazolium derivative (SM-1) salt with ion exchange from the (SM-0) was fabricated and characterized by proton-nuclear magnetic resonance (1H-NMR), carbon-nuclear magnetic resonance (13C-NMR), Fourier-transform infrared spectroscopy (FT-IR), electrospray ionization (EIS-MS), thermal analysis (TG), cyclic voltammetry (CV), and ultraviolet-visible spectroscopy (UV-vis), for electrolytes (liquid or dried) in the DSSC charge transportation mechanism. Carbon 161-167 SM1 Homo sapiens 36-40 34138321-5 2021 Finally, our optimized FTO/ZHA/CsPbBr3/carbon structure PDs showed high self-powered performance with a linear dynamic range of 120.3 dB, a detectivity of 4.2 x 1012 Jones, rise/fall time of 13/28 micros and the f-3 dB of up to 28 kHz. Carbon 39-45 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 23-26 11113459-4 2000 The catalytic efficiency (k(cat)/K(m)) of V104,A113 (VA) and V104,V113 (VV) variants of hGSTP1-1 was approximately 2.3- and 1.7-fold higher, respectively, than that of the I104,A113 (IA) isoform toward bay region isomer (+/-)-anti-B[c]C-1,2-diol-3,4-epoxide. Carbon 235-236 immunoglobulin lambda variable 1-40 Homo sapiens 61-70 11113459-4 2000 The catalytic efficiency (k(cat)/K(m)) of V104,A113 (VA) and V104,V113 (VV) variants of hGSTP1-1 was approximately 2.3- and 1.7-fold higher, respectively, than that of the I104,A113 (IA) isoform toward bay region isomer (+/-)-anti-B[c]C-1,2-diol-3,4-epoxide. Carbon 235-236 glutathione S-transferase pi 1 Homo sapiens 88-96 11603298-2 2000 FI0-c, and its sulfated derivative, FI0-c-S, on production of human proinflammatory cytokines, interleukin-1 alpha (IL-1 alpha) and tumor necrosis factor alpha (TNF alpha). Carbon 4-5 interleukin 1 alpha Homo sapiens 95-114 11603298-2 2000 FI0-c, and its sulfated derivative, FI0-c-S, on production of human proinflammatory cytokines, interleukin-1 alpha (IL-1 alpha) and tumor necrosis factor alpha (TNF alpha). Carbon 4-5 interleukin 1 alpha Homo sapiens 116-126 35567974-5 2022 This study presents a porous graphitic carbon liquid chromatography-orbitrap tandem mass spectrometry-based method that characterized 58 linear and 10 branched GOS and detected 59 non-reducing GOS from DP2 to DP6. Carbon 39-45 transcription factor Dp-2 Homo sapiens 202-205 31078062-2 2019 To do this, multiwalled carbon nanotube (MWCNT)/L-histidine functionalized reduced graphene oxide (His-rGO) was demonstrated as a bifunctional nanoplatform for covalently attaching thionine redox indicator and anti-PSA antibody (Ab). Carbon 24-30 kallikrein related peptidase 3 Homo sapiens 215-218 35452690-7 2022 Grass carp TARBP2 expression is significantly increased at 6h post-poly I:C stimulation in CIK cells and grass carp tissues, indicating that it may play a role in poly I:C-mediated immune response. Carbon 74-75 TARBP2 subunit of RISC loading complex Homo sapiens 11-17 35452690-7 2022 Grass carp TARBP2 expression is significantly increased at 6h post-poly I:C stimulation in CIK cells and grass carp tissues, indicating that it may play a role in poly I:C-mediated immune response. Carbon 170-171 TARBP2 subunit of RISC loading complex Homo sapiens 11-17 35302004-0 2022 A new method for measuring airborne elemental carbon using PUF disk passive samplers. Carbon 46-52 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 59-62 11082192-1 2000 In Saccharomyces cerevisiae, the existence of PYC1 and PYC2 encoding cytosolic pyruvate carboxylase isoform I and II is rather puzzling, owing to the lack of potent differential gene regulation by the carbon sources. Carbon 201-207 pyruvate carboxylase 1 Saccharomyces cerevisiae S288C 46-50 11082192-4 2000 These enzymatic changes were independent of the nature of the carbon source and closely correlated to the changes in beta-galactosidase from PYC1-lacZ gene fusion and in PYC1 transcripts. Carbon 62-68 pyruvate carboxylase 1 Saccharomyces cerevisiae S288C 141-145 11082192-4 2000 These enzymatic changes were independent of the nature of the carbon source and closely correlated to the changes in beta-galactosidase from PYC1-lacZ gene fusion and in PYC1 transcripts. Carbon 62-68 pyruvate carboxylase 1 Saccharomyces cerevisiae S288C 170-174 35302004-10 2022 This proof of concept of the PUF-PAS method provides an opportunity to cost-effectively expand measurements of elemental carbon at the global scale, and could be further extended to include other carbonaceous aerosol species in the future. Carbon 121-127 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 29-32 31041569-5 2019 We used poly(I:C)-treated nasal mucosal epithelial cells (HNECs) to find that the expression of KDM2B and Brg1 was also decreased, and the main expression position transferred from the nucleus to the nuclear membrane. Carbon 15-16 lysine demethylase 2B Homo sapiens 96-101 35218709-9 2022 When challenged with industrial wastewater containing 4-CP, chemical oxygen demand (COD) and total organic carbon removal efficiencies of 67.5% and 63.1% respectively could be obtained, accounting for energy consumption of 85.1 kWh kg COD-1 for degradation of 1 kg of COD in industrial wastewater. Carbon 107-113 component of oligomeric golgi complex 4 Homo sapiens 235-240 11073899-4 2000 Here we show, using DAL80 fused to the carbon-regulated GAL1,10 or copper-regulated CUP1 promoter, that GAT1 expression is inversely regulated by the level of DAL80 expression, i.e., as DAL80 expression increases, GAT1 expression decreases. Carbon 39-45 metallothionein CUP1 Saccharomyces cerevisiae S288C 84-88 35247814-3 2022 Herein, three carbon dots (CDs1 to CDs3) decorated modified-carbon nitride (CDs1-NCN, CDs2-NCN and CDs3-NCN) were designed and fabricated, which show diverse activity of H2O2 photoproduction. Carbon 14-20 CDP-diacylglycerol synthase 1 Homo sapiens 27-31 31289360-3 2019 Here we show MTHFD2, a mitochondrial enzyme involved in one-carbon metabolism, contributes to the progression of renal cell carcinoma (RCC) via a novel epitranscriptomic mechanism that involves HIF-2alpha. Carbon 60-66 endothelial PAS domain protein 1 Homo sapiens 194-204 35247814-3 2022 Herein, three carbon dots (CDs1 to CDs3) decorated modified-carbon nitride (CDs1-NCN, CDs2-NCN and CDs3-NCN) were designed and fabricated, which show diverse activity of H2O2 photoproduction. Carbon 14-20 CDP-diacylglycerol synthase 1 Homo sapiens 76-80 11123468-3 2000 The enzyme data obtained from this comparative study highlighted the strong spatial and temporal variability of the distribution of LAP in aquatic ecosystems, which was sometimes related to the course of environmental variables such as salinity and organic carbon content. Carbon 257-263 LAP Homo sapiens 132-135 10986267-1 2000 We have shown that the Escherichia coli phosphate-starvation-inducible psiE gene is regulated by both phosphate and the carbon source by using both lacZ and chloramphenicol acetyltransferase gene (cat) fusions. Carbon 120-126 chloramphenicol acetyltransferase Escherichia coli 157-190 35149072-5 2022 Increasing the chlorine dose increased double bond equivalent minus oxygen values of Cl1-DBPs and decreased the double bond equivalent minus oxygen values of Cl2-DBPs, while the nominal oxidant state of carbon decreased for Cl1-DBPs and increased for Cl2-DBPs. Carbon 203-209 adhesion G protein-coupled receptor L1 Homo sapiens 224-227 31289360-6 2019 Enhanced HIF-2alpha translation, in turn, promotes the aerobic glycolysis, linking one-carbon metabolism to HIF-2alpha-dependent metabolic reprogramming through RNA methylation. Carbon 87-93 endothelial PAS domain protein 1 Homo sapiens 9-19 31312984-0 2019 Theoretical study on the mechanism of N- and alpha-carbon oxidation of lapatinib catalyzed by cytochrome P450 monooxygenase. Carbon 51-57 cytochrome P450 family 20 subfamily A member 1 Homo sapiens 94-123 10992353-4 2000 He introduced new innovative art media, such as his carbon dust and stipple board technique to reproduce vivid tissue, while developing an instructive and didactic manner of medical illustration. Carbon 52-58 artemin Homo sapiens 29-32 33405737-3 2019 In the current study, we developed a simple hydrothermal method to prepare carbon quantum dots (CD) doped SPIONs (FeCD) from easily available precursors. Carbon 75-81 collagen type VIII alpha 2 chain Homo sapiens 114-118 11016849-2 2000 In S. cerevisiae, growth on all non-fermentable carbon sources requires Cat8p, a transcriptional activator that controls the expression of gluconeogenic and glyoxylate cycle genes via CSREs (Carbon Source Responsive Elements). Carbon 48-54 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 72-77 11016849-2 2000 In S. cerevisiae, growth on all non-fermentable carbon sources requires Cat8p, a transcriptional activator that controls the expression of gluconeogenic and glyoxylate cycle genes via CSREs (Carbon Source Responsive Elements). Carbon 191-197 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 72-77 11016849-3 2000 The down-regulation of Cat8p by fermentable carbon sources is the primary factor responsible for the tight repression of gluconeogenesis by glucose in S. cerevisiae. Carbon 44-50 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 23-28 30548553-1 2019 Carbon-based materials are often used as matrices for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and its imaging (MALDI-MSI). Carbon 0-6 RB binding protein 4, chromatin remodeling factor Homo sapiens 150-153 30548553-8 2019 CFP proved to be an effective one-step development and matrix application technique for MALDI-MSI of latent fingerprints, when carbon cluster peaks are well separated by a HRMS. Carbon 127-133 RB binding protein 4, chromatin remodeling factor Homo sapiens 94-97 10931309-5 2000 The gene is named GUP1 (glycerol uptake) and, for growth on glycerol, is important as a carbon and energy source. Carbon 88-94 O-acyltransferase Saccharomyces cerevisiae S288C 18-22 31048406-7 2019 We showed that expression of either human ortholog, COQ10A or COQ10B, rescues yeast coq10Delta mutant phenotypes, restoring the function of respiratory-dependent growth on a nonfermentable carbon source and sensitivity to oxidative stress induced by treatment with PUFAs. Carbon 189-195 coenzyme Q10A Homo sapiens 52-58 10929106-4 2000 In addition to AKIN10 and AKIN11, the deficiency of yeast snf4 mutant to grown on non-fermentable carbon source was suppressed by Arabidopsis Myb30, CAAT-binding factor Hap3b, casein kinase I, zinc-finger factors AZF2 and ZAT10, as well as orthologs of hexose/UDP-hexose transporters, calmodulin, SMC1-cohesin and Snf4. Carbon 98-104 AMP-activated serine/threonine-protein kinase regulatory subunit SNF4 Saccharomyces cerevisiae S288C 58-62 31048406-7 2019 We showed that expression of either human ortholog, COQ10A or COQ10B, rescues yeast coq10Delta mutant phenotypes, restoring the function of respiratory-dependent growth on a nonfermentable carbon source and sensitivity to oxidative stress induced by treatment with PUFAs. Carbon 189-195 coenzyme Q10B Homo sapiens 62-68 31289479-0 2019 Highly sensitive detection of CTLA-4-positive T-cell subgroups based on nanobody and fluorescent carbon quantum dots. Carbon 97-103 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 30-36 31289479-2 2019 In the present study, a rapid, succinct and efficient method was designed for the detection of CTLA-4+ human T cells using a CTLA-4-specific nanobody-fluorescent carbon quantum dots complex (QDs-Nb36). Carbon 162-168 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 95-101 10754252-2 2000 SK-3 was able to grow on 2-chlorobiphenyl, 3-chlorobiphenyl, 4-chlorobiphenyl (4-CB), chloroacetate and 4-chlorobenzoic acid (4-CBA) as sole carbon and energy sources. Carbon 141-147 potassium calcium-activated channel subfamily N member 3 Homo sapiens 0-4 31289479-2 2019 In the present study, a rapid, succinct and efficient method was designed for the detection of CTLA-4+ human T cells using a CTLA-4-specific nanobody-fluorescent carbon quantum dots complex (QDs-Nb36). Carbon 162-168 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 125-131 10744740-2 2000 First, two atp1 mutations (atp1-1 and atp1-2) were characterized that prevent the growth of yeast on non-fermentable carbon sources. Carbon 117-123 Atp11p Saccharomyces cerevisiae S288C 27-33 31248014-4 2019 In budding yeast Saccharomyces cerevisiae, deletion of the gene coding for mitochondrial translation initiation factor 3 - AIM23, leads to an imbalance in mitochondrial protein synthesis and significantly delays growth after shifting from fermentable to non-fermentable carbon sources. Carbon 270-276 Aim23p Saccharomyces cerevisiae S288C 123-128 11088174-4 2000 The critical thickness below which the predicted modulated phase occurs is found to be h(c)=-2L(a)[1-(1-2K(24)/K(11))(2)+K(*)(13)/K(11)], where L(a) is the polar anchoring extrapolation length, K11 and K24 are the standard Nehring-Saupe elastic constants, and K*13 is the effective elastic constant of the layer. Carbon 4-5 keratin 24 Homo sapiens 202-205 31018430-0 2019 Interaction between functionalized multiwalled carbon nanotubes and MS2 bacteriophages in water. Carbon 47-53 MS2 Homo sapiens 68-71 10655215-7 2000 Because expression of the GPR1 gene is known to be induced by nitrogen starvation, the Gpr1 receptor may serve as a dual sensor of abundant carbon source (sugar ligand) and nitrogen starvation. Carbon 140-146 Gpr1p Saccharomyces cerevisiae S288C 26-30 10655215-7 2000 Because expression of the GPR1 gene is known to be induced by nitrogen starvation, the Gpr1 receptor may serve as a dual sensor of abundant carbon source (sugar ligand) and nitrogen starvation. Carbon 140-146 Gpr1p Saccharomyces cerevisiae S288C 87-91 31018430-3 2019 This study systematically evaluates the interfacial interaction of acid-functionalized multiwalled carbon nanotubes (MWNTs) with MS2 bacteriophages, or heteroaggregation behavior of these particulates, under mono- and di-valent cations and with Suwannee River humic acid (SRHA). Carbon 99-105 MS2 Homo sapiens 129-132 30861440-1 2019 The bacterial (dissimilatory) iron and sulfate reduction (BIR and BSR) are intimately linked to the biogeochemical cycling of C, Fe, and S in acid mine drainage (AMD) environments. Carbon 126-127 maternally expressed 8, small nucleolar RNA host gene Homo sapiens 66-69 10708375-1 2000 Changing the growth mode of Saccharomyces cerevisiae by adding fermentable amounts of glucose to cells growing on a non-fermentable carbon source leads to rapid repression of general stress-responsive genes like HSP12. Carbon 132-138 lipid-binding protein HSP12 Saccharomyces cerevisiae S288C 212-217 30927596-3 2019 In this work, Rh3+, Ru3+, Pd2+ ions were impregnated on activated carbon derived from pumpkin stalk in distilled water and then reduced with sodium borohydride to form Rh0, Ru0, Pd0 nanoparticles on the surface of carbon. Carbon 66-72 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 26-29 10625697-4 2000 In contrast to rapidly proliferating cells, both Bcy1p and Tpk1p are distributed over nucleus and cytoplasm in cells growing on a nonfermentable carbon source or in stationary phase cells. Carbon 145-151 cAMP-dependent protein kinase regulatory subunit BCY1 Saccharomyces cerevisiae S288C 49-54 10625697-5 2000 These results demonstrate that at least two different mechanisms determine the subcellular localization of PKA; cAMP controls the localization of Tpk1p, and the carbon source determines that of Bcy1p. Carbon 161-167 cAMP-dependent protein kinase regulatory subunit BCY1 Saccharomyces cerevisiae S288C 194-199 30927596-3 2019 In this work, Rh3+, Ru3+, Pd2+ ions were impregnated on activated carbon derived from pumpkin stalk in distilled water and then reduced with sodium borohydride to form Rh0, Ru0, Pd0 nanoparticles on the surface of carbon. Carbon 214-220 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 26-29 31188867-0 2019 The Escherichia coli O157:H7 carbon starvation-inducible lipoprotein Slp contributes to initial adherence in vitro via the human polymeric immunoglobulin receptor. Carbon 29-35 polymeric immunoglobulin receptor Homo sapiens 129-162 10629208-3 2000 Mth1 is shown to be involved in carbon source-dependent regulation of its own, invertase and hexose transporter gene expression. Carbon 32-38 Mth1p Saccharomyces cerevisiae S288C 0-4 30959244-0 2019 Potential use of ZnO@activated carbon nanocomposites for the adsorptive removal of Cd2+ ions in aqueous solutions. Carbon 31-37 CD2 molecule Homo sapiens 83-86 10556063-7 1999 The Daf-c phenotype was suppressed by daf-7 cDNA expression or a daf-3 null mutation. Carbon 8-9 Smad protein daf-3 Caenorhabditis elegans 65-70 15822268-0 1999 [Study on the inkblot of carbon pen fields by Raman micro-spectroscopy]. Carbon 25-31 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 32-35 15822268-1 1999 The four carbon-pen inkblots in market were studied by Raman micro-spectroscopy. Carbon 9-15 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 16-19 30959244-6 2019 The ratio of ZnO nanoparticles and activated carbon was optimized to achieve enhanced electrostatic interactions for the effective adsorption of cadmium ions (Cd2+). Carbon 45-51 CD2 molecule Homo sapiens 159-162 31095140-1 2019 A precise ricin A-chain (RTA) delivery system was constructed by coupling RTA to carbon dots (CDs) with a distinctive capacity for Golgi targeting. Carbon 81-87 MAS related GPR family member F Homo sapiens 25-28 10482686-0 1999 Carbon and amino acids reciprocally modulate the expression of glutamine synthetase in Arabidopsis. Carbon 0-6 hypothetical protein Arabidopsis thaliana 63-83 31002522-3 2019 In the presence of nucleophiles, an attack took place on the C-1 or C-3 carbon regio- and stereoselectively depending on the nature of the nucleophiles. Carbon 72-78 heterogeneous nuclear ribonucleoprotein C Homo sapiens 61-71 10423385-12 1999 The new 3D S(3) TPPI TROSY HCCH method is demonstrated on a (13)C,(15)N-labeled protein sample, RAP 18-112 (N-terminal domain of alpha(2)-macroglobulin receptor associated protein), at 750 MHz and average sensitivity enhancements of 10% are obtained for the cross peaks in comparison to methods based on conventional decoupling on one of the carbons or on TROSY on both carbons. Carbon 370-377 LDL receptor related protein associated protein 1 Homo sapiens 96-99 30690513-1 2019 Studies have indicated that the carbon starvation response leads to the reprogramming of the transcriptome and metabolome, and many genes, including several important regulators, such as the group S1 basic leucine zipper transcription factors (TFs) bZIP1, bZIP11 and bZIP53, the SNAC-A TF ATAF1, etc., are involved in these physiological processes. Carbon 32-38 NAC (No Apical Meristem) domain transcriptional regulator superfamily protein Arabidopsis thaliana 289-294 10437916-2 1999 Here, we show that, in clonally derived mouse K1735 melanoma variant cell lines with high (M-2) and low (C-23) metastatic potential, elevated expression of alpha7 correlates with reduced cell motility, metastasis, and tumor growth. Carbon 105-106 integrin alpha 7 Mus musculus 156-162 31020858-0 2021 An electrochemical sensor for the determination of tartrazine based on CHIT/GO/MWCNTs/AuNPs composite film modified glassy carbon electrode. Carbon 123-129 chitinase 1 Homo sapiens 71-75 31020858-1 2021 A novel nanocomposite film of chitosan/graphene oxide (CHIT/GO)/multi-walled carbon nanotubes (MWCNTs)/gold nanoparticles (AuNPs) was applied to fabricate glassy carbon electrode (CHIT/GO/MWCNTs/AuNPs/GCE) for the determination of Tartrazine (TZ), synthetic dyes in food products. Carbon 162-168 chitinase 1 Homo sapiens 55-59 10353637-6 1999 The X-ray co-crystal structure of one of these analogues in complex with cathepsin K shows the inhibitor binding in the primed side of the enzyme active site with a covalent interaction between the active site cysteine 25 and the carbonyl carbon of the inhibitor. Carbon 230-236 cathepsin K Homo sapiens 73-84 30913382-5 2019 We discovered that only carbon nanoparticle-Pb2+ adducts, not other pollutants or adducts, induced inflammation in human bronchial cells by suppressing the expression of a novel long noncoding RNA lnc-PCK1-2:1, while lnc-PCK1-2:1 routinely plays a regulatory role in inhibiting inflammation. Carbon 24-30 phosphoenolpyruvate carboxykinase 1 Homo sapiens 201-205 10079079-6 1999 Thus, we isolated the DHS-22 binding factor from bovine brain nuclear extracts and finally identified it as NF90 on the basis of molecular mass analysis of Lys-C-digested fragments and amino acid sequences of the two peptides of the trypsin-digested binding protein. Carbon 160-161 interleukin enhancer binding factor 3 Homo sapiens 108-112 30913382-5 2019 We discovered that only carbon nanoparticle-Pb2+ adducts, not other pollutants or adducts, induced inflammation in human bronchial cells by suppressing the expression of a novel long noncoding RNA lnc-PCK1-2:1, while lnc-PCK1-2:1 routinely plays a regulatory role in inhibiting inflammation. Carbon 24-30 phosphoenolpyruvate carboxykinase 1 Homo sapiens 221-225 30942201-1 2019 This report demonstrates that changing the position of the carbon-metal bond in a polypyridyl cyclopalladated complex, i.e. going from PdL1 (N^N^C^N) to PdL2 (N^N^N^C), dramatically influences the photodynamic properties of the complex in cancer cells. Carbon 59-65 CD274 molecule Homo sapiens 135-139 10072687-1 1999 New, potent, and selective histamine H3 receptor antagonists have been synthesized by employing the use of (1) an appropriately positioned nonpolar acetylene spacer group, (2) either a two-carbon straight chain linker or a conformationally restricting trans-cyclopropane ring between the C-4 position of an imidazole headgroup and the acetylene spacer, and (3) a Topliss operational scheme for side-chain substitution for optimizing the hydrophobic domain. Carbon 189-195 histamine receptor H3 Homo sapiens 27-48 10102376-3 1999 Screening of two S. cerevisiae cDNA libraries led to the identification of CBT1 as a gene which, if overexpressed simultaneously with CDC14, results in the rescue of the dbJ2-2 mutation at restrictive temperature on galactose-based medium, as well as on media containing non-fermentable carbon sources such as glycerol, lactate and acetate. Carbon 287-293 phosphoprotein phosphatase CDC14 Saccharomyces cerevisiae S288C 134-139 10094465-5 1999 Protein binding to carbon source response elements of the ICL1 promoter was competed by all three elements to various extents by the respective ACR1 sequences. Carbon 19-25 Arr1p Saccharomyces cerevisiae S288C 144-148 30797108-2 2019 The electrochemical impedance spectroscopy (EIS) investigations surprisingly revealed that the glassy carbon electrode (GC) electrode modified with Chit-Naf composite had higher electron transfer kinetics compared the bare GC, GC/Naf and GC/Chit electrodes, which promises a great potential as an efficient platform in construction of biosensing assays. Carbon 102-108 chitinase 1 Homo sapiens 148-152 30797108-2 2019 The electrochemical impedance spectroscopy (EIS) investigations surprisingly revealed that the glassy carbon electrode (GC) electrode modified with Chit-Naf composite had higher electron transfer kinetics compared the bare GC, GC/Naf and GC/Chit electrodes, which promises a great potential as an efficient platform in construction of biosensing assays. Carbon 102-108 chitinase 1 Homo sapiens 241-245 10429832-5 1999 The levels of amylase activity in D. levanonensis and D. saltans were substantially low, indicating that these species cannot utilize starch as a carbon source. Carbon 146-152 Amylase proximal Drosophila melanogaster 14-21 30826652-3 2019 We obtained the excellent matrix material, which immobilized more primary antibody MCP-1-Ab1 on rGO-TEPA on a modified glassy carbon electrode (GCE). Carbon 126-132 C-C motif chemokine ligand 2 Homo sapiens 83-88 10721200-0 1999 General features of the Adriatic Sea: the key role of carbon cycling. Carbon 54-60 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 33-36 30849722-0 2019 A ratiometric fluorescence probe based on carbon dots for discriminative and highly sensitive detection of acetylcholinesterase and butyrylcholinesterase in human whole blood. Carbon 42-48 butyrylcholinesterase Homo sapiens 132-153 9894911-1 1998 Transcriptional regulation of the yeast cytochrome c1 gene (CYT1) in response to oxygen and carbon source is mediated by Haplp and the Hap2 complex. Carbon 92-98 transcription activator HAP2 Saccharomyces cerevisiae S288C 135-139 35595358-3 2022 In the present work, we report a facile strategy to obtain nitrogen and phosphorous co-doped glucose-derived carbon coated CoP nanowires (G-CoP/N,P-C NWs), in which nitrilotriacetic acid (NTA) was as the chelating reagent, glucose was as carbon source, and the precursors were subsequently experienced carbonization and phosphorization process. Carbon 109-115 caspase recruitment domain family member 16 Homo sapiens 123-126 35595358-3 2022 In the present work, we report a facile strategy to obtain nitrogen and phosphorous co-doped glucose-derived carbon coated CoP nanowires (G-CoP/N,P-C NWs), in which nitrilotriacetic acid (NTA) was as the chelating reagent, glucose was as carbon source, and the precursors were subsequently experienced carbonization and phosphorization process. Carbon 109-115 caspase recruitment domain family member 16 Homo sapiens 140-143 35595358-3 2022 In the present work, we report a facile strategy to obtain nitrogen and phosphorous co-doped glucose-derived carbon coated CoP nanowires (G-CoP/N,P-C NWs), in which nitrilotriacetic acid (NTA) was as the chelating reagent, glucose was as carbon source, and the precursors were subsequently experienced carbonization and phosphorization process. Carbon 238-244 caspase recruitment domain family member 16 Homo sapiens 123-126 35595358-3 2022 In the present work, we report a facile strategy to obtain nitrogen and phosphorous co-doped glucose-derived carbon coated CoP nanowires (G-CoP/N,P-C NWs), in which nitrilotriacetic acid (NTA) was as the chelating reagent, glucose was as carbon source, and the precursors were subsequently experienced carbonization and phosphorization process. Carbon 238-244 caspase recruitment domain family member 16 Homo sapiens 140-143 30849722-1 2019 A ratiometric fluorescence probe based on carbon dots (CDs) was developed for discriminative and highly sensitive detection of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activity in human whole blood. Carbon 42-48 butyrylcholinesterase Homo sapiens 159-180 35471629-3 2022 The proposed methodology uses the gold nanoparticles-modified carbon screen-printed electrode for immobilization of single-stranded DNA probe against miR-204. Carbon 62-68 microRNA 204 Homo sapiens 150-157 30849722-1 2019 A ratiometric fluorescence probe based on carbon dots (CDs) was developed for discriminative and highly sensitive detection of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activity in human whole blood. Carbon 42-48 butyrylcholinesterase Homo sapiens 182-186 31380163-0 2019 Iron-Salen Complex and Co2+ Ion-Derived Cobalt-Iron Hydroxide/Carbon Nanohybrid as an Efficient Oxygen Evolution Electrocatalyst. Carbon 62-68 complement C2 Homo sapiens 23-26 35636716-4 2022 Such BiONS were applied to modify the surface of screen-printed carbon electrodes (BiONS-SPCEs) for the development of a robust palladium (Pd2+) sensor. Carbon 64-70 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 139-142 35596011-3 2022 In this study, a single-atomic palladium-loaded nitrogen-doped porous carbon catalyst (SA-Pd/NPC) was prepared and used as a mimetic peroxidase to catalyze the substrates oxidation. Carbon 70-76 NPC intracellular cholesterol transporter 1 Homo sapiens 87-96 9811909-2 1998 Data supporting the notion that plants have a nitrogen regulatory system(s) includes previous studies showing that the levels of mRNA for plant nitrogen assimilatory genes such as glutamine synthetase (GLN) and asparagine synthetase (ASN) are modulated by carbon and organic nitrogen metabolites. Carbon 256-262 hypothetical protein Arabidopsis thaliana 180-200 9811909-2 1998 Data supporting the notion that plants have a nitrogen regulatory system(s) includes previous studies showing that the levels of mRNA for plant nitrogen assimilatory genes such as glutamine synthetase (GLN) and asparagine synthetase (ASN) are modulated by carbon and organic nitrogen metabolites. Carbon 256-262 hypothetical protein Arabidopsis thaliana 202-205 31380163-2 2019 Here, CoFe hydroxide/carbon nanohybrid is reported as an efficient oxygen evolution electrocatalyst derived from the in situ formed molecular Fe-salen complexes and Co2+ ions at a low temperature of 160 C. It has been evidenced that Fe-salen as a molecular precursor facilitates the confined-growth of metal hydroxides, while Co2+ plays a critical role in catalyzing the transformation of organic ligand into nanocarbons and constitutes an essential component for CoFe hydroxide. Carbon 21-27 complement C2 Homo sapiens 165-168 31380163-2 2019 Here, CoFe hydroxide/carbon nanohybrid is reported as an efficient oxygen evolution electrocatalyst derived from the in situ formed molecular Fe-salen complexes and Co2+ ions at a low temperature of 160 C. It has been evidenced that Fe-salen as a molecular precursor facilitates the confined-growth of metal hydroxides, while Co2+ plays a critical role in catalyzing the transformation of organic ligand into nanocarbons and constitutes an essential component for CoFe hydroxide. Carbon 21-27 complement C2 Homo sapiens 327-330 30728184-4 2019 Here we modeled mitochondrial overload by creating mice lacking the enzyme carnitine acetyltransferase (CrAT) in the proximal tubules, thus limiting a primary mechanism to export carbons under conditions of substrate excess. Carbon 179-186 carnitine acetyltransferase Mus musculus 75-102 9829590-0 1998 Quantitative analyses of carbonyl-carbon-11-WAY-100635 binding to central 5-hydroxytryptamine-1A receptors in man. Carbon 25-31 5-hydroxytryptamine receptor 1A Homo sapiens 74-96 35144170-0 2022 Molecularly imprinted polymer-based electrochemical impedimetric sensors on screen-printed carbon electrodes for the detection of trace cytokine IL-1beta. Carbon 91-97 interleukin 1 alpha Homo sapiens 145-153 35144170-1 2022 In this study, protein-imprinted sensors were electrochemically fabricated on screen-printed carbon electrodes (SPCEs) for the cytokine interleukin-1beta (IL-1beta) detection. Carbon 93-99 interleukin 1 alpha Homo sapiens 155-163 30728184-4 2019 Here we modeled mitochondrial overload by creating mice lacking the enzyme carnitine acetyltransferase (CrAT) in the proximal tubules, thus limiting a primary mechanism to export carbons under conditions of substrate excess. Carbon 179-186 carnitine acetyltransferase Mus musculus 104-108 35576645-6 2022 Solid-state hybrid supercapacitor (HSC) devices were manufactured using C-MSi, e-C-MSi (M = Zn and Mn), and activated carbon (AC) (denoted as C-MSi//AC and e-C-MSi//AC). Carbon 118-124 RB binding protein 4, chromatin remodeling factor Homo sapiens 144-147 9683671-5 1998 Moreover, the KlDLD gene is regulated by the product of KlHAP2, homologous to the HAP2 gene which in Saccharomyces cerevisiae is required for the induction of genes encoding mitochondrial components, upon shifting from a fermentable to a non-fermentable carbon source. Carbon 254-260 transcription activator HAP2 Saccharomyces cerevisiae S288C 58-62 30854431-4 2019 Integrating Dm-ChP with genomic and functional data, we have discovered an unexpected chromatin function for adenosylhomocysteinase, a major one-carbon pathway metabolic enzyme, in gene activation. Carbon 145-151 adenosylhomocysteinase Homo sapiens 109-131 9632383-0 1998 Black carbon in deep-Sea sediments Black carbon (BC) enters the ocean through aerosol and river deposition. Carbon 6-12 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 21-24 9632383-0 1998 Black carbon in deep-Sea sediments Black carbon (BC) enters the ocean through aerosol and river deposition. Carbon 7-13 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 21-24 35628747-4 2022 The biomass carbon of planktonic fungi exhibits spatiotemporal dynamics and can reach up to 1 mug CL-1 of seawater, rivaling bacteria on some occasions, which suggests their active and important role in the water column. Carbon 12-18 adhesion G protein-coupled receptor L1 Homo sapiens 98-102 30420622-7 2019 The clinical benefit of PCSK9 inhibitors seen in these trials occurred in the setting of reducing LDL-C levels to unprecedentedly low levels, suggesting that more aggressive LDL-C targets should be adopted. Carbon 101-103 proprotein convertase subtilisin/kexin type 9 Homo sapiens 24-29 35319113-3 2022 Here; the well-dispersed Ru nanoparticles with adjacent Ru single atoms on carbon substrate (Ru1,n -NC) is demonstrated to be a superb electrocatalyst for alkaline HER. Carbon 75-81 Scm like with four mbt domains 1 Homo sapiens 93-96 35471735-0 2022 Liquid Na/K Alloy Interfacial Synthesis of Functional Porous Carbon at Ambient Temperature. Carbon 61-67 TANK binding kinase 1 Homo sapiens 7-11 35471735-3 2022 Herein, a liquid metal interfacial engineering strategy is reported for the synthesis of porous carbon using CCl4 as the carbon precursor and sodium-potassium alloy (NaK) as the reducing agent, which is superior to traditional synthetic methods because it enables the engineering of a highly active liquid metal alloy microemulsion to directly generate porous carbon at ambient temperature. Carbon 96-102 TANK binding kinase 1 Homo sapiens 166-169 35471735-3 2022 Herein, a liquid metal interfacial engineering strategy is reported for the synthesis of porous carbon using CCl4 as the carbon precursor and sodium-potassium alloy (NaK) as the reducing agent, which is superior to traditional synthetic methods because it enables the engineering of a highly active liquid metal alloy microemulsion to directly generate porous carbon at ambient temperature. Carbon 360-366 TANK binding kinase 1 Homo sapiens 166-169 9614098-6 1998 The cls1::TRP1 null mutant grew on both fermentable and non-fermentable carbon sources but more poorly on the latter. Carbon 72-78 phosphoribosylanthranilate isomerase TRP1 Saccharomyces cerevisiae S288C 10-14 21781864-4 1998 While human CYP1A1, rat CYP1A1 and rat CYP1A2 formed almost exclusively the (-)-B[c]Ph-3R,4R-dihydrodiol, human CYP1A2 produced both the (-)-3R,4R- and the (+)-3S,4S-dihydrodiol enantiomers in a ratio of 2:1. Carbon 62-63 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 112-118 9587038-3 1998 The study of CSF metabolites in children with serial errors affecting the single-carbon transfer pathway has suggested that S-adenosylmethionine deficiency is a cause of the demyelination. Carbon 81-87 colony stimulating factor 2 Homo sapiens 13-16 30768077-3 2019 The application of this carbon on ITO/PEN substrates is also demonstrated. Carbon 24-30 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 38-41 35467257-0 2022 Unveiling the Bio-corona Fingerprinting of Potential Anticancer Carbon Nanotubes Coupled with D-Amino Acid Oxidase. Carbon 64-70 D-amino acid oxidase Homo sapiens 94-114 35467257-2 2022 For this purpose, d-amino acid oxidase (DAAO) from the yeast Rhodotorula gracilis, an enzyme able to efficiently catalyze the production of hydrogen peroxide from d-amino acids, was adsorbed onto multi-walled carbon nanotubes (MWCNTs), previously functionalized with polylactic-co-glycolic acid (PLGA) or polyethylene glycol (PEG) at different degrees to reduce their toxicity, to be targeted directly into the tumor. Carbon 209-215 D-amino acid oxidase Homo sapiens 18-38 35467257-2 2022 For this purpose, d-amino acid oxidase (DAAO) from the yeast Rhodotorula gracilis, an enzyme able to efficiently catalyze the production of hydrogen peroxide from d-amino acids, was adsorbed onto multi-walled carbon nanotubes (MWCNTs), previously functionalized with polylactic-co-glycolic acid (PLGA) or polyethylene glycol (PEG) at different degrees to reduce their toxicity, to be targeted directly into the tumor. Carbon 209-215 D-amino acid oxidase Homo sapiens 40-44 30794578-4 2019 Here, we demonstrate a bioelectronic device in which a lipid bilayer supported on H+-conducting Pd/PdHx contacts contains carbon nanotubes porin (CNTP) channels. Carbon 122-128 pyruvate dehydrogenase complex component X Homo sapiens 99-103 35388830-1 2022 Hydrazone-linked covalent organic framework-43 (COF-43) was synthesized and the carbon paste electrode (CPE) modified with this COF was used as a voltammetric sensor to measure silver(I). Carbon 80-86 carboxypeptidase E Homo sapiens 104-107 11672041-6 1998 The breaking of the bond between C-1 and C-2 carbons in pentose yields tetronic acids. Carbon 45-52 heterogeneous nuclear ribonucleoprotein C Homo sapiens 33-44 30718779-7 2019 Two STs (i) 3-DHFR 401 T > C-DHPS 96/98 - PJ1 and (ii) 3-DHFR 401 T > C-DHPS 96- PJ3 were significantly associated with treatment failure and high mortality among PCP-positive patients. Carbon 27-29 dihydrofolate reductase Homo sapiens 14-18 9417069-0 1998 Carbon flux via the pentose phosphate pathway regulates the hepatic expression of the glucose-6-phosphatase and phosphoenolpyruvate carboxykinase genes in conscious rats. Carbon 0-6 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 86-107 35394760-2 2022 In this work, FeOOH nanorod with intrinsic oxygen vacancy supported on carbon paper (FeOOH/CP) is proposed as a high-performance electrocatalyst for converting nitrate to ammonia at room temperature. Carbon 71-77 ceruloplasmin Homo sapiens 91-93 35388395-4 2022 Due to the lack of carbon sources provided by a Mo-MOF, the conductivity of MoP2-C cannot be greatly improved. Carbon 19-25 endothelial PAS domain protein 1 Homo sapiens 76-80 30718779-7 2019 Two STs (i) 3-DHFR 401 T > C-DHPS 96/98 - PJ1 and (ii) 3-DHFR 401 T > C-DHPS 96- PJ3 were significantly associated with treatment failure and high mortality among PCP-positive patients. Carbon 70-72 dihydrofolate reductase Homo sapiens 57-61 9891796-2 1998 In this pathway, two specific enzymes, isocitrate lyase and malate synthase, are activated to divert isocitrate from the tricarboxylic acid cycle and prevent the quantitative loss of acetate carbons as carbon dioxide. Carbon 191-198 citramalyl-CoA lyase Homo sapiens 60-75 30537235-1 2019 Sea level rise and changes in precipitation can cause saltwater intrusion into historically freshwater wetlands, leading to shifts in microbial metabolism that alter greenhouse gas emissions and soil carbon sequestration. Carbon 200-206 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 0-3 9398512-4 1997 The small energies required to displace the C-O bond 7 degrees from its energetically preferred upright geometry suggest that distortion of the surrounding protein, rather than the relatively undeformable Fe-C-O unit, is the main steric mechanism inhibiting CO binding to myoglobin. Carbon 44-45 myoglobin Homo sapiens 272-281 35411000-8 2022 Knockdown of CPT1A markedly lowers the fraction of 13C-palmitate-derived carbons into pyrimidine. Carbon 73-80 carnitine palmitoyltransferase 1a, liver Mus musculus 13-18 35333511-3 2022 Herein, we develop an efficient catalytic material composed of a single-atom Ru-N4 site and Ru nanoparticles anchored on nitrogen-doped carbon (Ru1+NPs/N-C) through the coordination-pyrolysis strategy of the melamine formaldehyde resin. Carbon 136-142 Scm like with four mbt domains 1 Homo sapiens 144-147 30956352-4 2019 As an illustration we refer to the example of an initial laboratory approach for establishing whether vibrationally excited SiC2 and HCN are the carriers of some of the unassigned features observed in the prototypical carbon rich AGB star IRC+10216 with ALMA. Carbon 218-224 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 133-136 35424826-5 2022 This paper presents an electrochemical deposition method to obtain cobalt oxides with a controllable crystallinity on carbon paper (CP). Carbon 118-124 ceruloplasmin Homo sapiens 132-134 9403173-7 1997 In contrast to GSTM1-1 and as previously shown for GSTA1-1, GSTP1-1 showed an exclusive preference for conjugation of the enantiomers with R-configuration at the benzylic oxirane carbon. Carbon 179-185 glutathione S-transferase pi 1 Homo sapiens 60-67 9403173-12 1997 Further, modeling of the enantiomers of anti- and syn-BPDE in the active site of GSTP1-1 provides an explanation for the exclusive preference for the enantiomers with R-configuration at the benzylic oxirane carbon. Carbon 207-213 glutathione S-transferase pi 1 Homo sapiens 81-88 9365926-0 1997 Sequential main-chain proton and carbon resonance assignments for wild-type yeast iso-1 ferrocytochrome c and identification of secondary structural elements. Carbon 33-39 threonine ammonia-lyase ILV1 Saccharomyces cerevisiae S288C 82-87 35264593-6 2022 Gene Ontology, KEGG, and MetaCore pathway analyses identified SIRT2 substrates involved in diverse pathways, including carbon metabolism, glycolysis, spliceosome, RNA transport, RNA binding, transcription, DNA damage response, the cell cycle, and colorectal cancer. Carbon 119-125 sirtuin 2 Homo sapiens 62-67 30650258-2 2019 The concentration of Pd2+ is the key factor for the density of Pd nanoparticles (Pd NPs) embedded in the carbon shells, which plays a role in the oxygen reduction reaction (ORR) and surface-enhanced Raman scattering (SERS) properties. Carbon 105-111 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 21-24 35359273-2 2022 In this study, an amperometric glucose biosensor (GOD/CS/PR/GCE) based on layer-by-layer of glucose oxidase (GOD), chitosan (CS) and pyrite (PR) on a glassy carbon electrode (GCE) was fabricated through electrostatic force. Carbon 157-163 aminomethyltransferase Homo sapiens 60-63 35359273-2 2022 In this study, an amperometric glucose biosensor (GOD/CS/PR/GCE) based on layer-by-layer of glucose oxidase (GOD), chitosan (CS) and pyrite (PR) on a glassy carbon electrode (GCE) was fabricated through electrostatic force. Carbon 157-163 aminomethyltransferase Homo sapiens 175-178 35064631-2 2022 Herein, an in situ integration engineering strategy of oxygen-vacancy and core-shell heterojunction to fabricate an anemone-like CoP@CoOOH core-shell heterojunction with rich oxygen-vacancies supported on carbon paper (CoP@CoOOH/CP), is described. Carbon 205-211 caspase recruitment domain family member 16 Homo sapiens 129-132 35064631-2 2022 Herein, an in situ integration engineering strategy of oxygen-vacancy and core-shell heterojunction to fabricate an anemone-like CoP@CoOOH core-shell heterojunction with rich oxygen-vacancies supported on carbon paper (CoP@CoOOH/CP), is described. Carbon 205-211 caspase recruitment domain family member 16 Homo sapiens 219-222 9378988-3 1997 The inhibitory effect of IFN-gamma on poly(I:C)-induced E-selectin was concentration and time dependent and was specific for dsRNA, in that the induction of E-selectin by TNF-alpha, IL-1 beta, thrombin, or LPS was not inhibited significantly by this pretreatment. Carbon 45-47 selectin E Homo sapiens 56-66 9378988-3 1997 The inhibitory effect of IFN-gamma on poly(I:C)-induced E-selectin was concentration and time dependent and was specific for dsRNA, in that the induction of E-selectin by TNF-alpha, IL-1 beta, thrombin, or LPS was not inhibited significantly by this pretreatment. Carbon 45-47 selectin E Homo sapiens 157-167 9315631-12 1997 In contrast, when the VDAC gene from Drosophila melanogaster was expressed in delta por1 yeast cells, VDAC-like channels could be detected in the mitochondria by both bilayer and liposome techniques, yet the cells failed to grow on glycerol at 37 degrees C. Thus, channel-forming activity does not seem to be either necessary or sufficient to restore growth on nonfermentable carbon sources, indicating that VDAC mediates cellular functions that do not depend on the ability to form channels. Carbon 376-382 porin Drosophila melanogaster 22-26 9315631-12 1997 In contrast, when the VDAC gene from Drosophila melanogaster was expressed in delta por1 yeast cells, VDAC-like channels could be detected in the mitochondria by both bilayer and liposome techniques, yet the cells failed to grow on glycerol at 37 degrees C. Thus, channel-forming activity does not seem to be either necessary or sufficient to restore growth on nonfermentable carbon sources, indicating that VDAC mediates cellular functions that do not depend on the ability to form channels. Carbon 376-382 porin Drosophila melanogaster 102-106 9315631-12 1997 In contrast, when the VDAC gene from Drosophila melanogaster was expressed in delta por1 yeast cells, VDAC-like channels could be detected in the mitochondria by both bilayer and liposome techniques, yet the cells failed to grow on glycerol at 37 degrees C. Thus, channel-forming activity does not seem to be either necessary or sufficient to restore growth on nonfermentable carbon sources, indicating that VDAC mediates cellular functions that do not depend on the ability to form channels. Carbon 376-382 porin Drosophila melanogaster 102-106 35402174-1 2022 Background: Serine hydroxymethyltransferase (SHMT) is critical for one-carbon unit metabolism and is increasingly reported to be associated with tumor patients" outcomes. Carbon 71-77 serine hydroxymethyltransferase 1 Homo sapiens 12-43 35402174-1 2022 Background: Serine hydroxymethyltransferase (SHMT) is critical for one-carbon unit metabolism and is increasingly reported to be associated with tumor patients" outcomes. Carbon 71-77 serine hydroxymethyltransferase 1 Homo sapiens 45-49 30800376-2 2019 In this study, the efficiency of inorganic composite-based multi-walled carbon nanotube (MWCNT) hybrid membranes was investigated in the removal of MS2 bacteriophages from contaminated water. Carbon 72-78 MS2 Homo sapiens 148-151 35157422-3 2022 A wearable strain sensor is fabricated by sandwiching the MAGP hydrogels between two dielectric carbon nanotubes (CNTs)/poly(dimethylsiloxane) (PDMS) layers, which can be utilized to monitor delicate and vigorous human motion. Carbon 96-102 microfibril associated protein 2 Homo sapiens 58-62 35164551-3 2022 Previous studies demonstrated a primary function for CreA/Cre1 in carbon metabolism; however, the phenotype of creA/cre1 mutants indicated broader roles. Carbon 66-72 Spt10p Saccharomyces cerevisiae S288C 58-62 9287326-7 1997 Interestingly, the rSUG1 ATPase activity was stimulated by poly(U) and poly(C), but not by poly(A), poly(G), or by any forms of DNAs tested. Carbon 76-77 proteasome 26S subunit, ATPase 5 Rattus norvegicus 19-24 30287180-8 2019 Furthermore, the electrocatalytic activity of YbMoSe2 modified glassy carbon electrode (YbMoSe2/GCE) toward the sensing of diphenylamine (DPA) anti-scald agent. Carbon 70-76 guanylate cyclase 2E, pseudogene Homo sapiens 88-99 9377092-1 1997 The monoamine oxidases A and B (MAO-A and MAO-B) catalyze the alpha-carbon oxidation of a variety of 4-substituted 1-methyl-1,2,3,6-tetrahydropyridine derivatives to yield the corresponding 2,3-dihydropyridinium species. Carbon 68-74 monoamine oxidase A Homo sapiens 4-30 9377092-1 1997 The monoamine oxidases A and B (MAO-A and MAO-B) catalyze the alpha-carbon oxidation of a variety of 4-substituted 1-methyl-1,2,3,6-tetrahydropyridine derivatives to yield the corresponding 2,3-dihydropyridinium species. Carbon 68-74 monoamine oxidase A Homo sapiens 32-37 35164551-3 2022 Previous studies demonstrated a primary function for CreA/Cre1 in carbon metabolism; however, the phenotype of creA/cre1 mutants indicated broader roles. Carbon 66-72 Spt10p Saccharomyces cerevisiae S288C 116-120 35164551-12 2022 In filamentous fungi, CCR is mediated by the conserved transcription factor CreA/Cre1, whose function in carbon metabolism has been well established. Carbon 105-111 Spt10p Saccharomyces cerevisiae S288C 81-85 35214859-2 2022 GLV are mainly 6-carbon molecules derived from fatty acids through the hydroperoxide lyase pathway and can serve as airborne signals to other parts of the same plant and to neighboring plants and help to protect them against biotic and abiotic stresses. Carbon 17-23 lyase Zea mays 85-90 35157147-4 2022 The biosensor was developed by covalently assembling the capture stands partially complementary to miR-21 on the gold nanoparticle-coated glassy carbon electrode. Carbon 145-151 microRNA 21 Homo sapiens 99-105 11902725-3 1997 SHMT catalyses interconversion of serine and glycine while transferring the resulting one-carbon unit into the C1 pool through methylene tetrahydrofolate. Carbon 90-96 serine hydroxymethyltransferase 1 Homo sapiens 0-4 30381394-6 2018 We also found that putative carbon-substrate flux between WT and mutant IDH1 subunits is inconsistent with the results of isotope tracing experiments in cancer cells harboring an endogenous monoallelic IDH1 mutation. Carbon 28-34 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 72-76 35077132-5 2022 The erosion rates and layer thicknesses were measured using differential interferometric profiling (DIP), demonstrating a close correlation between the coating thickness and the carbon/hydrogen gas ratio. Carbon 178-184 gastrin Homo sapiens 194-197 35135571-0 2022 Carbon dots hybrid for dual fluorescent detection of microRNA-21 integrated bioimaging of MCF-7 using a microfluidic platform. Carbon 0-6 microRNA 21 Homo sapiens 53-64 29389283-12 1997 Animals treated with c/s-platinum demonstrated significant elevation of DPOAE and ABR thresholds compared with control animals at 5 and 14 days. Carbon 21-23 ABR activator of RhoGEF and GTPase Homo sapiens 82-85 30381394-6 2018 We also found that putative carbon-substrate flux between WT and mutant IDH1 subunits is inconsistent with the results of isotope tracing experiments in cancer cells harboring an endogenous monoallelic IDH1 mutation. Carbon 28-34 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 202-206 30553726-4 2018 Our data highlighted the impact of the clock on metabolic regulation, with central carbon metabolism reflecting both transcriptional and post-transcriptional control and opposing metabolic pathways showing peak activities at different times of day. Carbon 83-89 solute carrier family 35 member G1 Homo sapiens 137-141 9079633-4 1997 RML2 is regulated transcriptionally in response to carbon source and the accumulation of Rml2p is dependent on the presence of the 21 S large rRNA. Carbon 51-57 mitochondrial 54S ribosomal protein RML2 Saccharomyces cerevisiae S288C 0-4 35114024-13 2022 CONCLUSION: Using HBECs challenged with viral infection mimic, Poly(I:C), we demonstrated that allergic sensitization to HDM was associated with impaired anti-viral immunity and that HDM exposure reduced anti-viral and anti-bacterial defense molecules, but not TSLP, across non-allergic as well as allergic asthma. Carbon 70-72 thymic stromal lymphopoietin Homo sapiens 261-265 35229526-5 2022 The gene abundance of methanogenic mcrA, sulfate-reducing bacteria Dsr, and carbon-fixing CbbL were significantly up-regulated in the LF, while that of methanotrophs pmoA, iron-reducing bacteria Geo, and denitrifying bacteria nosZ were significantly up-regulated in the LN, DCK and LCK, respectively. Carbon 76-82 LCK proto-oncogene, Src family tyrosine kinase Homo sapiens 282-285 30733623-7 2018 Under the conditions of protic catalysis, Cp2TiCl complexes with collidine hydrochloride and the titanium(III) center is less available for "cross-disproportionation" with carbon-centered radicals; this leads to by-products from radical capture by hydrogen atom transfer, resulting in a saturated alcohol. Carbon 172-178 ceruloplasmin Homo sapiens 42-45 35023736-2 2022 However, the introduction of dimethylamino but not methoxy substituents onto the exocyclic carbon atom changes the situation drastically so that the monomers (C5H4CH(NMe2))M(CO)3 and (C5H4C(NMe2)2)M(CO)3 become strongly thermochemically favored, lying DeltaE = 43 kcal/mol (M = W) to 63 kcal/mol (M = Cr) below their corresponding dimers. Carbon 91-97 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 166-170 35023736-2 2022 However, the introduction of dimethylamino but not methoxy substituents onto the exocyclic carbon atom changes the situation drastically so that the monomers (C5H4CH(NMe2))M(CO)3 and (C5H4C(NMe2)2)M(CO)3 become strongly thermochemically favored, lying DeltaE = 43 kcal/mol (M = W) to 63 kcal/mol (M = Cr) below their corresponding dimers. Carbon 91-97 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 190-194 35160474-2 2022 The capture and release capability of mineral clays (STx) and activated carbons (AC), pristine and modified (STx-L6 and AC-L6) with a linear penta-ethylene-hexamine (L6), towards solutions representative of the process, are assessed in the lab-scale. Carbon 81-83 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 Homo sapiens 109-112 9127195-3 1997 The synthesis, antibacterial activity and stability to human dehydropeptidase-1 (DHP-1) of three small series of carbapenems carrying carbon-linked substituents at C-2 are described. Carbon 134-140 complement C2 Homo sapiens 164-167 30404719-6 2018 Further, recently described potent histamine H3 receptor ligands - 4-tert-pentylphenoxyalkyl derivatives (with a 4-8 carbon spacer) - were evaluated for hMAO B inhibitory activity, and some of them displayed activity in the submicromolar range. Carbon 117-123 histamine receptor H3 Homo sapiens 35-56 9071738-11 1997 Based on E2 analogs bearing affinity-labeling groups, cysteine residues might be present in the binding site in the area of C-4, C-17 alpha, and C-17 beta, and a lysine residue might be located near C-16. Carbon 129-130 complement C4A (Rodgers blood group) Homo sapiens 124-127 9071738-11 1997 Based on E2 analogs bearing affinity-labeling groups, cysteine residues might be present in the binding site in the area of C-4, C-17 alpha, and C-17 beta, and a lysine residue might be located near C-16. Carbon 129-130 complement C4A (Rodgers blood group) Homo sapiens 124-127 35054626-0 2022 Analysis of Influencing Factors on the Gas Separation Performance of Carbon Molecular Sieve Membrane Using Machine Learning Technique. Carbon 69-75 gastrin Homo sapiens 39-42 35054626-1 2022 Gas separation performance of the carbon molecular sieve (CMS) membrane is influenced by multiple factors including the microstructural characteristics of carbon and gas properties. Carbon 34-40 gastrin Homo sapiens 0-3 35054626-1 2022 Gas separation performance of the carbon molecular sieve (CMS) membrane is influenced by multiple factors including the microstructural characteristics of carbon and gas properties. Carbon 34-40 gastrin Homo sapiens 166-169 35054626-1 2022 Gas separation performance of the carbon molecular sieve (CMS) membrane is influenced by multiple factors including the microstructural characteristics of carbon and gas properties. Carbon 155-161 gastrin Homo sapiens 0-3 35054626-4 2022 Based on the calculation results, the inferred key factors affecting the gas permeability of CMS membrane were the fractional free volume (FFV) of the precursor, the average interlayer spacing of graphite-like carbon sheet, and the final carbonization temperature. Carbon 210-216 gastrin Homo sapiens 73-76 35054626-5 2022 Moreover, the most influential factors for the gas separation performance were supposed to be the two structural factors of precursor influencing the porosity of CMS membrane, the carbon residue and the FFV, and the ratio of the gas kinetic diameters. Carbon 180-186 gastrin Homo sapiens 47-50 9523451-6 1997 A substantial improvement in BOD1/TOC could be achieved, but it required the mineralization of at least 80% of the organic carbon originally in the water. Carbon 123-129 biorientation of chromosomes in cell division 1 Homo sapiens 29-33 30558146-0 2018 Knockout of SlSBPASE Suppresses Carbon Assimilation and Alters Nitrogen Metabolism in Tomato Plants. Carbon 32-38 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 12-20 34978447-4 2022 To enhance the device performance of the FTO/SnO2/CsPbCl3 MCs/carbon structure UPD, a pressure-assisted annealing strategy was carried out, which reduced the void density and surface roughness of the microcrystal film. Carbon 62-68 FTO alpha-ketoglutarate dependent dioxygenase Homo sapiens 41-44 34989519-8 2022 There was a significant correlation between lg Koc and lg Kd (P<0.05), indicating that the organic carbon plays an important role in the distribution of the target PPCPs in water and sediments. Carbon 99-105 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 47-50 9144297-3 1997 Serum PAP levels (ng/ml) were significantly higher in group A (127.3 +/- 56.8) than in the other groups (B: 47.2 +/- 20.5; C: 51.5 +/- 32.2; D: 47 +/- 22.8; E: 27.6 +/- 9.0), which were not different from each other. Carbon 123-124 regenerating family member 3 alpha Homo sapiens 6-9 30558146-1 2018 Sedoheptulose-1,7-bisphosphatase (SBPase) is an enzyme in the Calvin-Benson cycle and has been documented to be important in carbon assimilation, growth and stress tolerance in plants. Carbon 125-131 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 0-32 30558146-1 2018 Sedoheptulose-1,7-bisphosphatase (SBPase) is an enzyme in the Calvin-Benson cycle and has been documented to be important in carbon assimilation, growth and stress tolerance in plants. Carbon 125-131 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 34-40 35071178-3 2021 Using the cytosolic SHMT from pig liver, we measured the natural carbon isotope ratios of both atoms involved in the bond splitting by chemical degradation of the remaining serine before and after partial turnover. Carbon 65-71 serine hydroxymethyltransferase 1 Sus scrofa 20-24 30558146-2 2018 However, information on the impact of SBPase on carbon assimilation and nitrogen metabolism in tomato plants (Solanum lycopersicum) is rather limited. Carbon 48-54 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 38-44 30558146-3 2018 In the present study, we investigated the role of SBPase in carbon assimilation and nitrogen metabolism in tomato plants by knocking out SBPase gene SlSBPASE using clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) gene editing technology. Carbon 60-66 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 50-56 35061932-7 2022 The characteristic genes of CD56+ NK cells were mainly enriched in the Jak-STAT signalling pathway and in cell adhesion molecules (24 h) and carbon metabolism (48 h). Carbon 141-147 neural cell adhesion molecule 1 Homo sapiens 28-32 30558146-5 2018 Further analyses showed that knockout of SlSBPASE led to a substantial reduction in SBPase activity and as a consequence, ribulose-1,5-bisphosphate (RuBP) regeneration and carbon assimilation rate were dramatically inhibited in slsbpase mutant plants. Carbon 172-178 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 41-49 8955358-2 1996 The transcripts of c-snoN were temporarily increased 25-fold above basal level at 12 h prior to the onset of transcription of muscle-specific gene, e.g. myogenin and muscle creatine kinase, whereas c-ski was expressed invariably. Carbon 9-10 SKI-like Mus musculus 21-25 30558146-8 2018 Collectively, our data suggest that SlSBPASE is required for optimal growth, carbon assimilation and nitrogen metabolism in tomato plants. Carbon 77-83 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 36-44 8955358-2 1996 The transcripts of c-snoN were temporarily increased 25-fold above basal level at 12 h prior to the onset of transcription of muscle-specific gene, e.g. myogenin and muscle creatine kinase, whereas c-ski was expressed invariably. Carbon 9-10 myogenin Mus musculus 153-161 31105987-2 2018 Most oxidations of chemicals are catalyzed by cytochrome P450 (P450, CYP) enzymes, which generally utilize mixed-function oxidase stoichiometry, utilizing pyridine nucleotides as electron donors: NAD(P)H + O2 + R NAD(P)+ + RO + H2O (where R is a carbon substrate and RO is an oxidized product). Carbon 248-254 peptidylprolyl isomerase G Homo sapiens 69-72 8917462-6 1996 The presence of two glycosidic substitutions on the Galp residue resulted in a strong overlapping of its proton signals, preventing direct assignment of both proton and carbon resonances. Carbon 169-175 galanin like peptide Homo sapiens 52-56 21619357-4 1996 As the chain length was reduced from C-18 to C-8 and C-4, the rate of diffusion also decreased. Carbon 37-38 complement C4A (Rodgers blood group) Homo sapiens 53-56 35069910-0 2022 PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis. Carbon 77-83 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 0-4 35069910-2 2022 In this study, we evaluated the role of PERK in the sensitivity of hepatocellular carcinoma (HCC) cells to high linear energy transfer (LET) carbon ions (CI). Carbon 141-147 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 40-44 31458308-1 2018 In this work, the catalytic activity of modified glassy carbon electrodes with xPd-yLaNi0.5Fe0.5O3-chitosan as an anodic catalyst for the polymeric fuel cell was investigated with cyclic voltammetry and controlled potential coulometry techniques; x and y are the mass loading of noble metal and mixed oxide, respectively. Carbon 56-62 ERCC excision repair 2, TFIIH core complex helicase subunit Homo sapiens 79-82 8925389-1 1996 Small-scale beds of granular activated carbon (GAC) have been tested in this research using challenges of volatile organic compounds (VOCs) in air at concentrations ranging from approximately 0.5 to 100 ppm. Carbon 39-45 glutaminase Homo sapiens 47-50 30173066-3 2018 Here, a fluidized three-dimensional electrode, containing granular activated carbon (GAC) particles, was constructed via MES. Carbon 77-83 glutaminase Homo sapiens 85-88 8709123-6 1996 The enzyme tolerates changing the C-4 oxygen of uridine to an amino group as well as substituting groups containing one or two carbons at C-5. Carbon 127-134 complement C5 Homo sapiens 138-141 8709123-7 1996 However, substitution of groups containing three carbons at C-5, or exchange of the pyrimidine for a purine, greatly weakens binding to the translocator. Carbon 49-56 complement C5 Homo sapiens 60-63 30064091-1 2018 In this work, Ni modified Pd nanoparticles immobilized on hollow nitrogen doped carbon spheres were successfully prepared, denoted as Pd/Ni-N/C. Carbon 80-86 ninein Homo sapiens 137-143 8764403-1 1996 The recombinant N-terminal 107-amino acid polypeptide fragment 2-108 of the DnaJ molecular chaperone of Escherichia coli, which contains the J-domain (residues 2 to 76) and the Gly/Phe-rich region (residues 77 to 108), was uniformly labeled with nitrogen-15 and carbon-13. Carbon 262-268 DnaJ Escherichia coli 76-80 30193639-1 2018 In this study, for the first time a rapid, selective and highly sensitive method was developed for simultaneous determination of warfarin and mycophenolic acid using carbon paste electrode modified by beta-cyclodextrin/multi-walled carbon nanotubes/cobalt oxide nanoparticles (beta-CD/MWCNTs/Co3O4NPs/CPE). Carbon 166-172 carboxypeptidase E Homo sapiens 301-304 30431044-3 2018 Herein, we employed a facile, low-cost and eco-friendly approach to construct a N,S co-doped hierarchical carbon nanomaterial (NSHC) via the pyrolysis of an azo-sulphonate dye pollutant intercalated layered double hydroxide. Carbon 106-112 SHC adaptor protein 3 Homo sapiens 127-131 8819169-7 1996 Of particular note is that negatively stained images of chaperonin adsorbed to a single carbon layer are distinctly different from those where it is sandwiched between two layers. Carbon 88-94 60 kDa heat shock protein, mitochondrial Oryctolagus cuniculus 56-66 11667173-1 1996 Compound 40 containing the C-1-C-21 region of tautomycin has been synthesized. Carbon 0-1 heterogeneous nuclear ribonucleoprotein C Homo sapiens 27-30 30431044-4 2018 The as-prepared NSHC possesses a two-dimensional hierarchical porous structure with ultrathin carbon nanosheets uniformly distributed on hexagonal carbon nanoplates, endowing the material with a high specific surface area of 1260 m2 g-1. Carbon 94-100 SHC adaptor protein 3 Homo sapiens 16-20 9172765-2 1996 (13)C NMR spectra show signals from the carbonyl, carboxyl, aromatic, and C alpha carbons in beta-casein, well resolved from solvent resonances. Carbon 82-89 casein beta Homo sapiens 93-104 9172765-3 1996 Only a small fraction of all carbon atoms in beta-casein contribute to detectable signals; intensity measurements show that the observable spectrum is derived from about 30 to 40 amino acid residues. Carbon 29-35 casein beta Homo sapiens 45-56 30431044-4 2018 The as-prepared NSHC possesses a two-dimensional hierarchical porous structure with ultrathin carbon nanosheets uniformly distributed on hexagonal carbon nanoplates, endowing the material with a high specific surface area of 1260 m2 g-1. Carbon 147-153 SHC adaptor protein 3 Homo sapiens 16-20 31458247-3 2018 Milling with SiN alleviates this issue but generates more nondiamond carbon. Carbon 69-75 embryonal Fyn-associated substrate Homo sapiens 13-16 30467610-0 2018 Amperometric Biosensor of Matrix Metalloproteinase-7 Enhanced by Pd-Functionalized Carbon Nanocomposites. Carbon 83-89 matrix metallopeptidase 7 Homo sapiens 26-52 30467610-2 2018 In this work, a Pd-functionalised carbon nanocomposite was designed as a new impedance enhancer for an amperometric sensor of MMP-7. Carbon 34-40 matrix metallopeptidase 7 Homo sapiens 126-131 8641288-2 1996 A disruption of both MSN2 and MSN4 genes results in a higher sensitivity to different stresses, including carbon source starvation, heat shock and severe osmotic and oxidative stresses. Carbon 106-112 stress-responsive transcriptional activator MSN2 Saccharomyces cerevisiae S288C 21-25 30463360-3 2018 In the present study, we tested the hypothesis that sedoheptulose-1,7-bisphosphatase (SBPase), an enzyme functioning in the photosynthetic carbon fixation in the Calvin-Benson cycle, was involved in methyl jasmonate (MeJA)- and dark-induced leaf senescence in tomato plants. Carbon 139-145 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 52-84 8606156-1 1996 In Saccharomyces cerevisiae, carbon and nitrogen metabolisms are connected via the incorporation of ammonia into glutamate; this reaction is catalyzed by the NADP-dependent glutamate dehydrogenase (NADP-GDH) encoded by the GDH1 gene. Carbon 29-35 glutamate dehydrogenase (NADP(+)) GDH1 Saccharomyces cerevisiae S288C 223-227 30463360-3 2018 In the present study, we tested the hypothesis that sedoheptulose-1,7-bisphosphatase (SBPase), an enzyme functioning in the photosynthetic carbon fixation in the Calvin-Benson cycle, was involved in methyl jasmonate (MeJA)- and dark-induced leaf senescence in tomato plants. Carbon 139-145 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 86-92 8606156-4 1996 Expression of GDH1 is also regulated by the carbon source, i.e., expression is higher on lactate than on ethanol, glycerol, or galactose, with the lowest expression being found on glucose. Carbon 44-50 glutamate dehydrogenase (NADP(+)) GDH1 Saccharomyces cerevisiae S288C 14-18 30359022-3 2018 The key intermediate is assumed to be one, where both the aldehyde (via oxygen) and the eta1 allyl group are coordinated to the metal center, and C-C bond formation between the terminal allylic carbon and carbonyl carbon is the rate-determining step. Carbon 146-147 secreted phosphoprotein 1 Homo sapiens 88-92 8606156-6 1996 The HAP complex is known to regulate expression of several genes involved in carbon metabolism; its role in the control of GDH1 gene expression, therefore, provides evidence for a cross-pathway regulation between carbon and nitrogen metabolisms. Carbon 77-83 glutamate dehydrogenase (NADP(+)) GDH1 Saccharomyces cerevisiae S288C 123-127 8606156-6 1996 The HAP complex is known to regulate expression of several genes involved in carbon metabolism; its role in the control of GDH1 gene expression, therefore, provides evidence for a cross-pathway regulation between carbon and nitrogen metabolisms. Carbon 213-219 glutamate dehydrogenase (NADP(+)) GDH1 Saccharomyces cerevisiae S288C 123-127 30359022-3 2018 The key intermediate is assumed to be one, where both the aldehyde (via oxygen) and the eta1 allyl group are coordinated to the metal center, and C-C bond formation between the terminal allylic carbon and carbonyl carbon is the rate-determining step. Carbon 194-200 secreted phosphoprotein 1 Homo sapiens 88-92 8600988-7 1996 These compounds have a saturated double bond in the polyene side chain between either the 7, 8 or 9, 10 carbon atoms and are highly RAR or RXR selective, respectively (as shown by receptor binding, transactivation activity and the ability to induce RXR homodimer formation). Carbon 104-110 retinoic acid receptor alpha Homo sapiens 132-135 30359022-3 2018 The key intermediate is assumed to be one, where both the aldehyde (via oxygen) and the eta1 allyl group are coordinated to the metal center, and C-C bond formation between the terminal allylic carbon and carbonyl carbon is the rate-determining step. Carbon 205-211 secreted phosphoprotein 1 Homo sapiens 88-92 8830055-7 1996 The carbon chain length specificity of very-long-chain acyl-CoA synthetase differed from that of long-chain acyl-CoA synthetase. Carbon 4-10 solute carrier family 27 member 2 Rattus norvegicus 39-74 30442778-0 2018 SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism. Carbon 61-67 sideroflexin 1 Homo sapiens 0-5 8720394-2 1996 The stereochemistry of a double bond at C-20(22) of ginsenoside Rh4 was characterized as (E) from a NOESY experiment in the 1H-NMR of the aglycone. Carbon 40-41 Rh blood group D antigen Homo sapiens 64-67 30442778-4 2018 Like cells missing mitochondrial components of one-carbon metabolism, those null for SFXN1 are defective in glycine and purine synthesis. Carbon 51-57 sideroflexin 1 Homo sapiens 85-90 30442778-7 2018 Thus, SFXN1 functions as a mitochondrial serine transporter in one-carbon metabolism. Carbon 67-73 sideroflexin 1 Homo sapiens 6-11 30394475-3 2018 In this work, LiBC has been synthesized by a solid-state method using different carbon precursors of acetylene black and graphite, marked a-LiBC and g-LiBC, respectively, and their electrochemical properties and corresponding structure evolutions have been investigated in Li-ion batteries. Carbon 80-86 cellular communication network factor 6 Homo sapiens 14-18 27414513-11 1996 Some of the products appeared to have an hydroxyl group as a substituent, all of them contained chlorine and only one contained carbon from CCl4. Carbon 128-134 C-C motif chemokine ligand 4 Homo sapiens 140-144 30394475-8 2018 Therefore, the specific capacity of LiBC is closely related to its crystallinity, and LiBC with amorphous carbon precursors could be adopted as a promising anode material for Li-ion batteries. Carbon 106-112 cellular communication network factor 6 Homo sapiens 36-40 30394475-8 2018 Therefore, the specific capacity of LiBC is closely related to its crystallinity, and LiBC with amorphous carbon precursors could be adopted as a promising anode material for Li-ion batteries. Carbon 106-112 cellular communication network factor 6 Homo sapiens 86-90 11666187-0 1996 Thermolysis of Neopentylcobalamin Analogs Complexed to Haptocorrin: Side Chain Entropy and Activation of Organocobalamins for Carbon-Cobalt Bond Homolysis. Carbon 126-132 transcobalamin 1 Homo sapiens 55-66 30360067-6 2018 Furthermore, the lower formation energy of L12 Cu3Pt combined with the enhanced antioxygenation of Pt provide Pt-o-Cu3Pt/C with a superior durability, showing only a 12.5% loss in mass activity after 5000 potential cycles. Carbon 47-48 ribosomal protein L12 Homo sapiens 43-46 30195263-6 2018 It is hypothesized that the free phosphate group affects the microenvironment around the target cytosine by activating the incoming nucleophile through hydrogen bonding with the water molecule, thus facilitating nucleophilic attack on the cytosine C-4 carbon. Carbon 252-258 complement C4A (Rodgers blood group) Homo sapiens 248-251 30151686-1 2018 A novel platform for carbamate-based pesticide quantification using a chitosan/magnetic iron oxide (Chit-Fe3O4) nanocomposite as a glassy carbon electrode (GCE) modifier is shown for an analytical methodology for determination of bendiocarb (BND). Carbon 138-144 chitinase 1 Homo sapiens 100-104 30005407-7 2018 Carbon ion beams irradiation up-regulated the expression levels of C-REPEAT BINDING FACTORS (CBFs), INDUCER OF CBF EXPRESSION 1 (ICE1), ICE2, CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 3 (CAMTA3) and cold-regulated COR genes, in response to cold stress. Carbon 0-6 basic helix-loop-helix (bHLH) DNA-binding superfamily protein Arabidopsis thaliana 136-140 30295304-2 2018 The bond path for the weak eta1-H(17)-C(17)Hg agostic interactions between the Hg center and H(17) in complexes 4-9 was a through-space interaction from Hg to agostic carbon [C(17)] followed by a through-bond interaction from C(17) to an agostic proton [H(17)]. Carbon 167-173 secreted phosphoprotein 1 Homo sapiens 27-31 30295304-2 2018 The bond path for the weak eta1-H(17)-C(17)Hg agostic interactions between the Hg center and H(17) in complexes 4-9 was a through-space interaction from Hg to agostic carbon [C(17)] followed by a through-bond interaction from C(17) to an agostic proton [H(17)]. Carbon 38-39 secreted phosphoprotein 1 Homo sapiens 27-31 30295304-2 2018 The bond path for the weak eta1-H(17)-C(17)Hg agostic interactions between the Hg center and H(17) in complexes 4-9 was a through-space interaction from Hg to agostic carbon [C(17)] followed by a through-bond interaction from C(17) to an agostic proton [H(17)]. Carbon 175-176 secreted phosphoprotein 1 Homo sapiens 27-31 29803050-7 2018 It showed that size distributions of high-temperature carbon fraction such as OC4, OP and EC1 were almost unimodal during all seasons as well as SO42- and NH4+, in contrast, that of lower temperature carbon fraction (OC1-OC3), Mg2+, and Ca2+ appear like bimodal. Carbon 54-60 Susceptibility to lysis by alloreactive natural killer cells Homo sapiens 90-93 30292205-5 2018 Finally, by utilizing C 1s single and double core-ionization potentials, initial and final state effects for the two inequivalent carbon atoms have been investigated. Carbon 130-136 heterogeneous nuclear ribonucleoprotein C Homo sapiens 22-25 29801604-1 2018 In this work, glassy carbon electrode (GCE) surface was modified by drop-coating graphene oxide (GO) and nile blue (NB) to form GO/NB/GCE. Carbon 21-27 aminomethyltransferase Homo sapiens 39-42 29801604-1 2018 In this work, glassy carbon electrode (GCE) surface was modified by drop-coating graphene oxide (GO) and nile blue (NB) to form GO/NB/GCE. Carbon 21-27 aminomethyltransferase Homo sapiens 128-137 30182099-1 2018 A more reliable/eco-friendly secondary Zn-Mn battery system is built with highly active Mn3O4@carbon nanowires and near-neutral electrolytes. Carbon 94-100 ciliogenesis associated kinase 1 Homo sapiens 16-19 30254290-0 2018 Shallow carbon storage in ancient buried thermokarst in the South Kara Sea. Carbon 8-14 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 71-74 30249059-1 2018 Post-treatment removal of dispersion agents from carbon nanotube/rubber composites can greatly enhance the mechanical properties by increasing the filler-matrix interaction. Carbon 49-55 solute carrier family 35 member G1 Homo sapiens 0-4 30014554-1 2018 This report widens the repertoire of emerging PdI catalysis to carbon-heteroatom, that is, C-S bond formation. Carbon 63-69 peptidyl arginine deiminase 1 Homo sapiens 46-49 30224633-2 2018 In this strategy, a floating electrode (FE)-based carbon nanotube (CNT) field effect transistor (FET) was functionalized with human olfactory receptor 1A2 (hOR1A2)-embedded NDs (hOR1A2NDs). Carbon 50-56 olfactory receptor family 1 subfamily A member 2 Homo sapiens 132-154 30224633-2 2018 In this strategy, a floating electrode (FE)-based carbon nanotube (CNT) field effect transistor (FET) was functionalized with human olfactory receptor 1A2 (hOR1A2)-embedded NDs (hOR1A2NDs). Carbon 50-56 olfactory receptor family 1 subfamily A member 2 Homo sapiens 156-162 30201999-1 2018 The mobilization of glacial permafrost carbon during the last glacial-interglacial transition has been suggested by indirect evidence to be an additional and significant source of greenhouse gases to the atmosphere, especially at times of rapid sea-level rise. Carbon 39-45 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 245-248 30201999-2 2018 Here we present the first direct evidence for the release of ancient carbon from degrading permafrost in East Asia during the last 17 kyrs, using biomarkers and radiocarbon dating of terrigenous material found in two sediment cores from the Okhotsk Sea. Carbon 69-75 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 249-252 30201999-3 2018 Upscaling our results to the whole Arctic shelf area, we show by carbon cycle simulations that deglacial permafrost-carbon release through sea-level rise likely contributed significantly to the changes in atmospheric CO2 around 14.6 and 11.5 kyrs BP. Carbon 65-71 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 139-142 30201999-3 2018 Upscaling our results to the whole Arctic shelf area, we show by carbon cycle simulations that deglacial permafrost-carbon release through sea-level rise likely contributed significantly to the changes in atmospheric CO2 around 14.6 and 11.5 kyrs BP. Carbon 116-122 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 139-142 30205487-0 2018 Preparation of Highly Catalytic N-Doped Carbon Dots and Their Application in SERS Sulfate Sensing. Carbon 40-46 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 77-81 30113165-8 2018 In one of them, the imine adopts an uncommon eta1(N)eta2(C,N) bridging mode of the ligand to nickel, while the second one may involve reactivity on the ligand by the formation of a new C-C bond by oxidative coupling. Carbon 57-58 secreted phosphoprotein 1 Homo sapiens 45-49 30113165-8 2018 In one of them, the imine adopts an uncommon eta1(N)eta2(C,N) bridging mode of the ligand to nickel, while the second one may involve reactivity on the ligand by the formation of a new C-C bond by oxidative coupling. Carbon 185-186 secreted phosphoprotein 1 Homo sapiens 45-49 8768667-6 1996 The present results suggest that the passing time of CCl4 molecules through the thin activated carbon layer of respirator cartridge may be too short to attain an adsorption equilibrium. Carbon 95-101 C-C motif chemokine ligand 4 Homo sapiens 53-57 30177713-3 2018 The electrochemical activity of the PET-AC modified glassy carbon electrode (GCE) (PET-AC/GCE) was measured by cyclic voltammetry and amperometry. Carbon 59-65 aminomethyltransferase Homo sapiens 77-80 8848442-4 1996 These results, in conjunction with findings on other structurally similar molecules suggest that, of the molecules tested, (a) a hydrophobic group at the C-3 attached carbon is critical for analgesia; (b) a hydrophobic C-2 ester group can enhance analgesic activity (e.g., cocaethylene); (c) the N-methyl position is minimally important for analgesia; and (d) isomeric configurational changes can influence analgesia. Carbon 167-173 complement C2 Rattus norvegicus 219-222 30177713-3 2018 The electrochemical activity of the PET-AC modified glassy carbon electrode (GCE) (PET-AC/GCE) was measured by cyclic voltammetry and amperometry. Carbon 59-65 aminomethyltransferase Homo sapiens 83-93 29946932-11 2018 Their prevalence in shallow-sea and suboxic estuarine sediments rather than deep-sea sediments hints that their metabolic properties of carbon metabolism are adapted to carbon substrates in these environments. Carbon 136-142 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 28-31 7578038-6 1995 The data are consistent with acylation of the active site serine, loss of p-hydroxybenzeneacetic acid, and formation of a carbinolamine at the carbon deriving from C-4 of the lactam ring. Carbon 143-149 complement C4A (Rodgers blood group) Homo sapiens 164-167 7594623-7 1995 Flow cytometry analysis of Poly I:C-stimulated, MACS enriched, NK1.1+ spleen cells revealed the presence of two subpopulations: one consisting of LGL and the other consisting of smaller, agranular lymphocytes (SAL). Carbon 34-35 tachykinin 1 Mus musculus 63-66 29946932-11 2018 Their prevalence in shallow-sea and suboxic estuarine sediments rather than deep-sea sediments hints that their metabolic properties of carbon metabolism are adapted to carbon substrates in these environments. Carbon 169-175 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 28-31 29803556-3 2018 Redox homeostasis, free-radical detoxification and one-carbon metabolism (Methionine-Hcy-Folate cycle) require CBS and its deficiency leads to hyperhomocysteinemia (HHcy) causing retinovascular thromboembolism and eye-lens dislocation along with vascular cognitive impairment and dementia. Carbon 55-61 cystathionine beta-synthase Mus musculus 111-114 30105116-5 2018 The role of AMT protein is pivotal for the synthesis of 5,10-methylene tetrahydrofolate, the first metabolite in one-carbon metabolism that regulates DNA synthesis, repair, and methylation. Carbon 117-123 aminomethyltransferase Homo sapiens 12-15 8596431-7 1995 In contrast to S. cerevisiae, additional elements and factors in K. lactis, distinct from Abf1p, Cpf1p and Hap2/3/4p, are able to activate transcription of the QCR8 gene during both fermentative and non-fermentative growth, as well as to induce transcription during growth on non-fermentable carbon sources. Carbon 292-298 ubiquinol--cytochrome-c reductase subunit 8 Saccharomyces cerevisiae S288C 160-164 29710586-0 2018 Efficient removal of Cd2+ and Pb2+ from aqueous solution with amino- and thiol-functionalized activated carbon: Isotherm and kinetics modeling. Carbon 104-110 CD2 molecule Homo sapiens 21-24 7655447-7 1995 Gradual exercise resulted in an increase of NPY-ir in ESH (from 14.4 +/- 5.8 to 18.1 +/- 6.4 and 20.7 +/- 8.1 fmol/ml p = 0.036, p = 0.02) and in C (from 11.7 +/- 4.6 to 13.4 +/- 5.0 and 15.2 +/- 5.9 fmol/ml, p < 0.01). Carbon 146-147 neuropeptide Y Homo sapiens 44-47 30159031-9 2018 Expression levels of GAL2 during growth on l-arabinose reached up to 21% of those obtained with d-galactose as sole carbon and energy source. Carbon 116-122 galactose permease GAL2 Saccharomyces cerevisiae S288C 21-25 7601860-3 1995 In particular, the cbpA dnaJ double-null mutant was found to exhibit severe defects in cell growth, namely, a very narrow temperature range for growth, a defect in cell division, and susceptibility to killing by carbon starvation. Carbon 212-218 DnaJ Escherichia coli 24-28 29680869-5 2018 Analysis of key enzymes demonstrated that the activities of phosphoenolpyruvate carboxylase, citrate synthase, aspartokinase and epsilon-PL synthetase were all increased in chemostat culture with the mixed carbon source. Carbon 206-212 phosphoenolpyruvate carboxykinase 1 Homo sapiens 60-91 7630919-7 1995 Oxidation of the two benzylic carbon atoms of alpha, alpha"-bis[3-(N,N-diethylcarbamoyl)piperidino]-p-xylene.2HBr (A-1) to form 1,4-bis[3-N,N-diethylcarbamoyl) piperidino]benzenedicarboxamide (A-40K), which has a second set of carbonyl oxygens but lacks basic N atoms, resulted in a remarkable loss of ADP-antagonist potency while retaining PAF-antagonist activity. Carbon 30-36 PCNA clamp associated factor Homo sapiens 341-344 7730379-4 1995 The qsr mutants require QCR6 for viability on fermentable and non-fermentable carbon sources, indicating that QCR6 is covering lethal mutations in qsr1 and qsr2, even when the yeast do not require respiration. Carbon 78-84 ribosomal 60S subunit protein L10 Saccharomyces cerevisiae S288C 147-151 7730379-8 1995 When one chromosomal copy of QSR1 was deleted in a diploid yeast strain, haploid spores derived therefrom and carrying the deletion were unable to grow on fermentable or non-fermentable carbon sources. Carbon 186-192 ribosomal 60S subunit protein L10 Saccharomyces cerevisiae S288C 29-33 29797241-7 2018 CONCLUSIONS: The central role of PKM2 in directing the flow of carbon between catabolic (ATP-producing) and anabolic processes provides unique opportunities for extending the therapeutic window of currently available and/or novel anti-neoplastic agents. Carbon 63-69 pyruvate kinase M1/2 Homo sapiens 33-37 7758938-2 1995 Experimental evidence indicated that the cloned fragment codes for proline dehydrogenase (EC 1.5.99.8) since RM2 cells transformed with a plasmid containing this sequence was able to survive on minimal medium supplemented with proline as the sole nitrogen and carbon sources. Carbon 260-266 proline dehydrogenase Mus musculus 67-88 30061486-0 2018 N,P-Codoped Carbon Layer Coupled with MoP Nanoparticles as an Efficient Electrocatalyst for Hydrogen Evolution Reaction. Carbon 12-18 opioid receptor mu 1 Homo sapiens 38-41 7891685-6 1995 The cat8 mutants also failed to derepress UAS2FBP1, and these mutants were unable to grow on nonfermentable carbon sources. Carbon 108-114 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 4-8 30061486-2 2018 In this work, an N,P-codoped carbon layer coupled with MoP nanoparticles (MoP/NPCs) was prepared through a facile high-temperature pyrolysis treatment. Carbon 29-35 opioid receptor mu 1 Homo sapiens 74-77 29627528-4 2018 We detected 11 single nucleotide polymorphisms (SNP) of 7 one-carbon metabolism pathway genes (including MTHFR, MTR, MTRR, ALDH1L1, GART, SHMT1 and CBS) in donor livers and analyzed their association with HBV reinfection after liver transplantation. Carbon 62-68 serine hydroxymethyltransferase 1 Homo sapiens 138-143 7732723-3 1995 In this paper, we describe the transcriptional regulation of the HXK1, HXK2 and GLK1 genes in the hope of revealing differences in the steady-state levels of mRNA associated with a particular carbon source used in the culture medium. Carbon 192-198 hexokinase 2 Saccharomyces cerevisiae S288C 71-75 29882652-3 2018 The FSC was assembled using lignosulfonate/single-walled carbon nanotubeHNO3 (Lig/SWCNTHNO3) pressure-sensitive hydrogels as electrodes and cellulose hydrogels as an electrolyte separator. Carbon 57-63 ubiquitin conjugating enzyme E2 K Homo sapiens 78-81 7695328-2 1995 The compounds, alkanoylcholines with hydrocarbon chains of 10 to 14 carbon atoms, are hydrolyzed by butyrylcholine esterase, which is present in human serum and mucosal membranes. Carbon 42-48 butyrylcholinesterase Homo sapiens 100-123 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 MYC proto-oncogene, bHLH transcription factor Homo sapiens 185-188 7881558-3 1994 A five-member mixed culture was established in a chemostat, comprising species with minimal glycosidase and protease activity, in which hog gastric mucin was the major carbon and energy source. Carbon 168-174 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 140-153 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 solute carrier family 7 member 5 Homo sapiens 210-216 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 solute carrier family 16 member 3 Homo sapiens 218-225 7961949-2 1994 Their models are very similar to that of the bovine retinol.RBP complex: the root mean square deviations between equivalent alpha-carbons in the two proteins range from 0.17 to 0.24 A. Carbon 130-137 retinol binding protein 4 Bos taurus 60-63 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 238-241 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 malate dehydrogenase 1 Homo sapiens 243-247 30440627-0 2018 Increased Conductivity and Reduced Settling Time of Carbon-Based Electrodes By Addition of Sea Salt for Wearable Application. Carbon 52-58 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 91-94 7958728-9 1994 The similarity of these ED50 data suggest that they share a similar chemical structure that binds to the 5-HT1A receptor, most likely it is "N-C-C-C-C-N" aliphatic backbone. Carbon 143-144 5-hydroxytryptamine receptor 1A Homo sapiens 105-120 30440627-13 2018 In summary, when carbon-based electrodes are used to measure bio-signals from skin surface for wearable application, its settling time can be partially offset by adding sea salt to CB/PDMS electrode and by making it thinner. Carbon 17-23 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 169-172 29689442-0 2018 Ameliorating mitochondrial dysfunction restores carbon ion-induced cognitive deficits via co-activation of NRF2 and PINK1 signaling pathway. Carbon 48-54 PTEN induced putative kinase 1 Mus musculus 116-121 7515048-3 1994 In the present study, we describe the inhibition of L- and P-selectin function by inositol polyanions, simple 6-carbon ring structures that have multiple ester-linked phosphate or sulfate groups. Carbon 112-118 selectin P Homo sapiens 59-69 29689442-7 2018 Furthermore, in the mouse hippocampal neuronal cells, overexpression of NRF2/PINK1 strikingly protected the hippocampal neurons from carbon ion-elicited toxic insults. Carbon 133-139 PTEN induced putative kinase 1 Mus musculus 77-82 29689442-8 2018 Thus, these data suggest that alleviation of the sustained mitochondrial dysfunction and oxidative stress through co-modulation of NRF2 and PINK1 may be in charge of restoration of the cognitive impairments in a mouse model of high-LET carbon ion irradiation. Carbon 236-242 PTEN induced putative kinase 1 Mus musculus 140-145 8030784-4 1994 However, if a double bond is present at the C-2 or C-3 carbon atoms, this cis=CH stretch absorption shows a hypsochromic shift to 3029-3028 and 3018-3017 cm-1, respectively. Carbon 55-61 complement C2 Homo sapiens 44-47 29567564-3 2018 By employing Au nanoparticles- and CdSe@CdS quantum dots-contained magnetic nanocomposites as electrochemical labels along with the polythiophene/reduced graphene oxide-modified carbon electrodes, this dual signal nanobiosensor showed a considerable performance in quantifying miR-106a (a GC oncogenic miRNA) and let-7a (a GC tumor suppressor miRNA). Carbon 178-184 microRNA 106a Homo sapiens 277-285 8184966-1 1994 Hepatocyte monolayers from neonatal calves were used to determine the effects of glucagon and insulin on incorporation of carbon from [2-14C]propionate, [1-14C]lactate, [U-14C]lactate, and [1,3-14C]glycerol into glucose and glycogen. Carbon 122-128 insulin Bos taurus 94-101 29718568-0 2018 An Exceptionally Efficient Co-Co2 P@N, P-Codoped Carbon Hybrid Catalyst for Visible Light-Driven CO2 -to-CO Conversion. Carbon 49-55 complement C2 Homo sapiens 30-33 8087890-3 1994 One of them, sci1-1, is recessive and caused inability to grow on non-fermentable carbon sources and to de-repress fructose-1,6-bisphosphatase. Carbon 82-88 AMP-activated serine/threonine-protein kinase regulatory subunit SNF4 Saccharomyces cerevisiae S288C 13-19 29691154-3 2018 Elongation of the two-carbon bridge to three-, four- or five-carbon bridges, and also saturation of the carbon bridges, provided compounds with good inhibitory activity against recombinant human DHFR (rhDHFR). Carbon 22-28 dihydrofolate reductase Homo sapiens 195-199 8137461-6 1994 Liver platinum levels measured at 2 h, 2 days, 6 days and 10 days after a single oral dose at the MTD ranged widely (from 15 to 109 micrograms platinum/g), were related to the number of carbon atoms in the axial dicarboxylate and alicyclic amine groups (r = 0.9389) and showed a diversity of time-course profiles. Carbon 186-192 metallothionein 1E Homo sapiens 98-101 29633498-3 2018 Herein, the preparation of CoP/CoP2 composite nanoparticles encapsulated within N,P-doped carbon nanotubes (CoP/CoP2 @NPCNTs) is demonstrated as a synergistic electrocatalyst for OER via the calcination of a CoAl-layered double hydroxide/melamine mixture and subsequent phosphorization. Carbon 90-96 caspase recruitment domain family member 16 Homo sapiens 27-30 7931241-6 1994 In the case of the initial, non-covalent, inhibition all these compounds were competitive inhibitors of MAO-A, with respect to the amine substrate, and the affinity for inhibitor binding increased with carbon chain length. Carbon 202-208 monoamine oxidase A Homo sapiens 104-109 7931241-10 1994 The time-dependent irreversible inhibition (measured as the IC50 values after 60 min enzyme-inhibitor preincubation) showed that the potency towards MAO-A increased when the side-chain length was increased from 2 to 3 carbons but that there was no significant difference between the 3 and 4 carbon-chain compounds. Carbon 218-225 monoamine oxidase A Homo sapiens 149-154 7931241-10 1994 The time-dependent irreversible inhibition (measured as the IC50 values after 60 min enzyme-inhibitor preincubation) showed that the potency towards MAO-A increased when the side-chain length was increased from 2 to 3 carbons but that there was no significant difference between the 3 and 4 carbon-chain compounds. Carbon 218-224 monoamine oxidase A Homo sapiens 149-154 29633498-3 2018 Herein, the preparation of CoP/CoP2 composite nanoparticles encapsulated within N,P-doped carbon nanotubes (CoP/CoP2 @NPCNTs) is demonstrated as a synergistic electrocatalyst for OER via the calcination of a CoAl-layered double hydroxide/melamine mixture and subsequent phosphorization. Carbon 90-96 caspase recruitment domain family member 16 Homo sapiens 31-34 8264631-8 1994 These results are consistent with the existence of an extragenic factor that binds the ADR1c region and represses ADR1 activity and suggest that other factors are responsible for aiding ADR1 in the carbon source regulation of ADH2. Carbon 198-204 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 226-230 29655281-2 2018 Herein, it is demonstrated that strongly coupled carbon nanosheets/molybdenum carbide (alpha-MoC1-x ) nanocluster hierarchical hybrid hollow spheres (denoted as MoC1-x /HSC) can work well as cathode for boosting the performance of lithium-O2 batteries. Carbon 49-55 fucosyltransferase 1 (H blood group) Homo sapiens 169-172 8227049-4 1993 The model of the retinoid-RBP complex is nearly identical to that of bovine retinol-RBP complex; the root mean square deviations between the alpha-carbons in the two proteins is 0.15 A. Carbon 147-154 retinol binding protein 4 Bos taurus 26-29 8227049-4 1993 The model of the retinoid-RBP complex is nearly identical to that of bovine retinol-RBP complex; the root mean square deviations between the alpha-carbons in the two proteins is 0.15 A. Carbon 147-154 retinol binding protein 4 Bos taurus 84-87 8275502-1 1993 2,6-Dihydropyran-3-ones carrying substituents at C-2 and C-6 in cis-arrangement invariably adopt half-chair conformations in which the ring oxygen and the carbon atom next to the carbonyl group are above and below, respectively, the plane formed by the other four carbon atoms, i.e., the 2Ho or oH2 conformation. Carbon 155-161 complement C2 Homo sapiens 49-52 29655281-3 2018 The important feature of MoC1-x /HSC is that the alpha-MoC1-x nanoclusters, uniformly incorporated into carbon nanosheets, can not only effectively prevent the nanoclusters from agglomeration, but also help enhance the interaction between the nanoclusters and the conductive substrate during the charge and discharge process. Carbon 104-110 fucosyltransferase 1 (H blood group) Homo sapiens 33-36 29658174-3 2018 Here, the rational design of carbon paper (CP) with N-doped carbon nanotubes (NCNTs) as a 3D host to obtain Na@CP-NCNTs composites electrodes for NMBs is demonstrated. Carbon 29-35 synuclein alpha Homo sapiens 108-113 29658174-3 2018 Here, the rational design of carbon paper (CP) with N-doped carbon nanotubes (NCNTs) as a 3D host to obtain Na@CP-NCNTs composites electrodes for NMBs is demonstrated. Carbon 60-66 synuclein alpha Homo sapiens 108-113 29443459-0 2018 Tunable Bifunctional Activity of Mnx Co3-x O4 Nanocrystals Decorated on Carbon Nanotubes for Oxygen Electrocatalysis. Carbon 72-78 keratin 86 Homo sapiens 33-36 8275502-1 1993 2,6-Dihydropyran-3-ones carrying substituents at C-2 and C-6 in cis-arrangement invariably adopt half-chair conformations in which the ring oxygen and the carbon atom next to the carbonyl group are above and below, respectively, the plane formed by the other four carbon atoms, i.e., the 2Ho or oH2 conformation. Carbon 179-185 complement C2 Homo sapiens 49-52 29443459-3 2018 Herein, the comprehensive development of manganese cobalt oxide/nitrogen-doped multiwalled carbon nanotube hybrids (Mnx Co3-x O4 @NCNTs) is reported for highly reversible oxygen reduction and evolution reactions (ORR and OER, respectively). Carbon 91-97 keratin 86 Homo sapiens 116-119 29537254-6 2018 Ascaroside production in strains with deletion, nonsense, and missense mutations in other acox genes demonstrates that ACOX-1.1 works with ACOX-1.3 in processing ascarosides with 7-carbon side chains, ACOX-1.4 in processing ascarosides with 9- and 11-carbon side chains, and ACOX-3 in processing ascarosides with 13- and 15-carbon side chains. Carbon 181-187 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 90-94 8413229-4 1993 The steady-state levels of HSP78 transcripts and protein varied in response to both thermal stress and carbon source with an approximately 30-fold difference between repressed levels in cells growing fermentatively on glucose at 30 degrees C and derepressed levels in heat-shocked cells growing on a nonfermentable carbon source. Carbon 103-109 chaperone ATPase HSP78 Saccharomyces cerevisiae S288C 27-32 8413229-4 1993 The steady-state levels of HSP78 transcripts and protein varied in response to both thermal stress and carbon source with an approximately 30-fold difference between repressed levels in cells growing fermentatively on glucose at 30 degrees C and derepressed levels in heat-shocked cells growing on a nonfermentable carbon source. Carbon 315-321 chaperone ATPase HSP78 Saccharomyces cerevisiae S288C 27-32 29537254-6 2018 Ascaroside production in strains with deletion, nonsense, and missense mutations in other acox genes demonstrates that ACOX-1.1 works with ACOX-1.3 in processing ascarosides with 7-carbon side chains, ACOX-1.4 in processing ascarosides with 9- and 11-carbon side chains, and ACOX-3 in processing ascarosides with 13- and 15-carbon side chains. Carbon 181-187 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 119-125 19912946-2 1993 The sole source of CO in mammalian systems is the alpha-meso carbon bridge of the heme molecule cleaved by heme oxygenase isozymes, HO-1 and HO-2. Carbon 61-67 heme oxygenase 1 Homo sapiens 132-145 29537254-6 2018 Ascaroside production in strains with deletion, nonsense, and missense mutations in other acox genes demonstrates that ACOX-1.1 works with ACOX-1.3 in processing ascarosides with 7-carbon side chains, ACOX-1.4 in processing ascarosides with 9- and 11-carbon side chains, and ACOX-3 in processing ascarosides with 13- and 15-carbon side chains. Carbon 251-257 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 90-94 29537254-6 2018 Ascaroside production in strains with deletion, nonsense, and missense mutations in other acox genes demonstrates that ACOX-1.1 works with ACOX-1.3 in processing ascarosides with 7-carbon side chains, ACOX-1.4 in processing ascarosides with 9- and 11-carbon side chains, and ACOX-3 in processing ascarosides with 13- and 15-carbon side chains. Carbon 251-257 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 119-125 29537254-6 2018 Ascaroside production in strains with deletion, nonsense, and missense mutations in other acox genes demonstrates that ACOX-1.1 works with ACOX-1.3 in processing ascarosides with 7-carbon side chains, ACOX-1.4 in processing ascarosides with 9- and 11-carbon side chains, and ACOX-3 in processing ascarosides with 13- and 15-carbon side chains. Carbon 251-257 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 90-94 8363583-0 1993 Effect of lead acetate and carbon particles on the expression of glutathione S-transferase YfYf in rat liver. Carbon 27-33 hematopoietic prostaglandin D synthase Rattus norvegicus 65-90 8363583-2 1993 The earliest response, an elevation of GST expression in Kupffer cells, can be mimicked by administering a suspension of carbon particles. Carbon 121-127 hematopoietic prostaglandin D synthase Rattus norvegicus 39-42 29537254-6 2018 Ascaroside production in strains with deletion, nonsense, and missense mutations in other acox genes demonstrates that ACOX-1.1 works with ACOX-1.3 in processing ascarosides with 7-carbon side chains, ACOX-1.4 in processing ascarosides with 9- and 11-carbon side chains, and ACOX-3 in processing ascarosides with 13- and 15-carbon side chains. Carbon 251-257 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 119-125 29537254-7 2018 It also shows that ACOX-1.2, but not ACOX-1.1, processes ascarosides with 5-carbon omega-side chains. Carbon 76-82 Acyl-coenzyme A oxidase acox-1.1 Caenorhabditis elegans 19-25 29202438-2 2018 In present work, a spatial-resolved dual-signal-output electrochemiluminescent (ECL) ratiometric assay platform was constructed for sensitive detection of prostate specific antigen (PSA) on a dual-disk glassy carbon electrode. Carbon 209-215 kallikrein related peptidase 3 Homo sapiens 182-185 8387597-4 1993 Structures of the new compounds are distinguished by changes in NMR chemical shifts of 13C and 1H nuclei in the regions of C-4 and C-12. Carbon 89-90 complement component 4B (Chido blood group) Mus musculus 123-126 29642896-9 2018 In IBB14LA1_5, the effect of the carbon source on YLA was less pronounced (~ 0.80 g g Xyl-1 , and 0.67 g g Glc-1 ). Carbon 33-39 GTPase-activating protein IRA1 Saccharomyces cerevisiae S288C 107-112 8466903-4 1993 Further, experiments with the gamma-L-glutamyl-DL-cysteinylglycine labeled with deuterium on the alpha- or beta-carbons to the sulfur showed small amounts of internal transfer of hydrogen into C-2 of the drug from the naturally occurring L,L diastereomer only. Carbon 112-119 complement C2 Homo sapiens 193-196 31458635-7 2018 Lap shear test was performed to analyze adhesion between the modified epoxy and carbon fiber. Carbon 80-86 LAP Homo sapiens 0-3 8464869-2 1993 However, it has been suggested that the ADE3-encoded C1-THF synthase does not play a role in providing the enzymes involved in the generation of one-carbon intermediates in the biosynthesis of the purine bases but functions in maintaining the structural integrity of the enzyme complex involved in purine biosynthesis [Barlowe, C. K. & Appling, D. A. Carbon 149-155 trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 Saccharomyces cerevisiae S288C 40-44 29631591-12 2018 Moreover, P HSP12 also led to moderate yEGFP expression when xylose was used as the sole carbon source, indicating that this promoter could be used for inducing proper gene expression for xylose utilization. Carbon 89-95 lipid-binding protein HSP12 Saccharomyces cerevisiae S288C 12-17 29424476-2 2018 This approach provides a unique methodology involving a site-selective C-N bond formation for preparation of C-2 substituted nitro indoles. Carbon 71-72 complement C2 Homo sapiens 109-112 1427091-8 1992 In addition to their inability to metabolize FA, the dfr1 strains are unable to grow on medium containing the non-fermentable carbon source glycerol, suggesting that the DFR1 gene product is also required for mitochondrial function. Carbon 126-132 dihydrofolate reductase Saccharomyces cerevisiae S288C 53-57 29680559-0 2018 High total organic carbon in surface waters of the northern Arabian Gulf: Implications for the oxygen minimum zone of the Arabian Sea. Carbon 19-25 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 130-133 1279359-8 1992 Shortening the distance between crb and RBS-C by three nucleotides reduced induction by half and a deletion of nine nucleotides abolished induction. Carbon 44-45 establishment of sister chromatid cohesion N-acetyltransferase 2 Homo sapiens 40-43 29500232-2 2018 Heme synthesis and degradation converge in a linear pathway that utilizes TCA cycle-derived carbon in cataplerotic reactions of tetrapyrrole biosynthesis, terminated by NAD(P)H-dependent biliverdin reductases (IXalpha, BLVRA and IXbeta, BLVRB) that lead to bilirubin generation and cellular antioxidant functions. Carbon 92-98 biliverdin reductase B Homo sapiens 237-242 1406189-3 1992 Today"s skis, poles, and boots use the latest in space-age synthetics including carbon and Kevlar fibers, which has resulted in an unprecedented advance in ski equipment technology, producing ultralight yet strong equipment. Carbon 80-86 SKI proto-oncogene Homo sapiens 8-11 1324938-2 1992 Shifting a yeast culture growing with acetate to medium containing glucose as a carbon source resulted in a 25-fold increase in turnover of MDH2. Carbon 80-86 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 140-144 1324938-4 1992 Measurements of malate dehydrogenase specific activity and determination of growth rates with diagnostic carbon sources indicated that the truncated form of MDH2 was expressed at authentic MDH2 levels and was fully active. Carbon 105-111 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 157-161 29511248-0 2018 Publisher Correction: Carbon nanowalls as a platform for biological SERS studies. Carbon 22-28 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 68-72 1325386-15 1992 The arginine tRNA gene, named HSX1, is essential for growth on a nonfermentable carbon source at high temperatures and for synthesis of the SSC1 heat shock protein. Carbon 80-86 HSX1 Saccharomyces cerevisiae S288C 30-34 29392380-4 2018 When used for non-enzymatic glucose detection, the 3D Co3O4-HPND/CNTs modified glassy carbon electrode (3D Co3O4-HPND/CNTs/GCE) exhibited excellent analytical performance with high sensitivity (22.21 mA mM-1 cm-2), low detection limit of 0.35 muM (S/N = 3), fast response (less than 5 s) and good stability. Carbon 86-92 aminomethyltransferase Homo sapiens 123-126 1495179-4 1992 The slope of linear regression line of latencies versus nasopharyngeal temperature was -1.05 msec.degrees C-1 for P27 (r = -0.93), -1.47 msec.degrees C-1 for P40 (r = -0.95) and -0.43 msec.degrees C-1 for P40-P27 (r = -0.78). Carbon 106-107 interferon alpha inducible protein 27 Homo sapiens 114-117 29127188-3 2018 We demonstrated that advanced NASH and NASH-related liver carcinogenesis are characterized by a significant dysregulation of 1-carbon homeostasis, with diminished expression of key 1-carbon metabolism genes, especially a marked inhibition of the S-adenosylhomocysteine hydrolase ( Ahcy) gene and an increased level of S-adenosyl-l-homocysteine (SAH). Carbon 183-189 adenosylhomocysteinase Homo sapiens 246-278 1319496-2 1992 Under anaerobic conditions, one-electron oxidants (ferricytochrome c, peroxidase/H2O2, ceruloplasmin, Cu2+) generate a radical intermediate. Carbon 14-15 ceruloplasmin Homo sapiens 87-100 29364137-6 2018 The lateral-penumbra width at the SOBP region was less than 2 mm for the carbon knife. Carbon 73-79 sine oculis binding protein homolog Homo sapiens 34-38 16668864-1 1992 Our aim was to determine whether fixation of inorganic carbon (C(i)), due to phosphoenolpyruvate carboxylase activity, is limited by the availability of C(i) in the cytoplasm of maize (Zea mays L.) root tips. Carbon 55-61 MLO-like protein 4 Zea mays 77-108 16668864-1 1992 Our aim was to determine whether fixation of inorganic carbon (C(i)), due to phosphoenolpyruvate carboxylase activity, is limited by the availability of C(i) in the cytoplasm of maize (Zea mays L.) root tips. Carbon 63-64 MLO-like protein 4 Zea mays 77-108 29416063-2 2018 Here, we show that Pemt and Gnmt, key one-carbon cycle genes regulating PC/SAM levels, are downregulated after feeding, leading to decreased PC and increased SAM levels, but these effects are blunted in small heterodimer partner (SHP)-null or FGF15-null mice. Carbon 42-48 fibroblast growth factor 15 Mus musculus 243-248 29874763-0 2018 Mesoporous carbon for efficient removal of microcystin-LR in drinking water sources, Nak-Dong River, South Korea: Application to a field-scale drinking water treatment plant. Carbon 11-17 TANK binding kinase 1 Homo sapiens 85-88 1579492-1 1992 URS1 is known to be a repressor binding site in Saccharomyces cerevisiae that negatively regulates expression of many genes including CAR1 (arginase), several required for sporulation, mating type switching, inositol metabolism, and oxidative carbon metabolism. Carbon 243-249 arginase Saccharomyces cerevisiae S288C 134-138 1326413-6 1992 The ser1 ser2 ser10 triple mutants were totally serine auxotrophic on glucose media but serine prototrophic during growth on non-fermentable carbon sources. Carbon 141-147 O-phospho-L-serine:2-oxoglutarate transaminase Saccharomyces cerevisiae S288C 4-13 29354815-2 2018 CoP nanoparticles anchored on N,P-dual-doped mesoporous graphene-like carbon (CoP@NPMG) acts as an outstanding bifunctional electrocatalyst for both the hydrogen evolution reaction and the oxygen evolution reaction over a wide pH range. Carbon 70-76 caspase recruitment domain family member 16 Homo sapiens 78-81 29594482-0 2018 Myoglobin immobilized on mesoporous carbon foam in a hydrogel (selep) dispersant for voltammetric sensing of hydrogen peroxide. Carbon 36-42 myoglobin Homo sapiens 0-9 1608042-4 1992 The clearance-rate of carbon was shortened by the oral administration of COB-L or COB-G (50 or 200 mg/kg). Carbon 22-28 cordon-bleu WH2 repeat Mus musculus 73-78 1740442-3 1992 We recently reported that GTP-binding proteins encoded by rab1B (GGCC), rab2 (GGCC), and rab5 (CCSN) are modified by 20-carbon isoprenyl derivatives of [3H]mevalonate when translated in vitro, despite having carboxyl-terminal sequences distinct from the Caa(M/S/L) motif. Carbon 120-126 RAB5A, member RAS oncogene family Homo sapiens 89-93 29594482-4 2018 Finally, myoglobin was immobilized on the composite and then placed on a glassy carbon electrode (GCE). Carbon 80-86 myoglobin Homo sapiens 9-18 28753296-2 2018 We have modified our previously described PEGylated-hydrophilic carbon clusters (PEG-HCCs) so that the epidermal growth factor receptor (EGFR) binding peptide, GE11, is attached using click chemistry at the end of each PEG. Carbon 64-70 epidermal growth factor receptor Mus musculus 103-135 27759198-11 1992 The r2 s were 0.89 and 0.76 with RMS errors in these carbon values of 10 and 18 mg m-3 h-1 . Carbon 53-59 H1.5 linker histone, cluster member Homo sapiens 88-91 1664298-7 1991 We have also found that null alleles of certain STE genes (ste7, ste11 and ste12), known to affect cell-type specific gene expression and expression of some Ty-adjacent genes, have a clear effect on Ty-controlled ADH2 expression depending on the carbon source. Carbon 246-252 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 213-217 28753296-2 2018 We have modified our previously described PEGylated-hydrophilic carbon clusters (PEG-HCCs) so that the epidermal growth factor receptor (EGFR) binding peptide, GE11, is attached using click chemistry at the end of each PEG. Carbon 64-70 epidermal growth factor receptor Mus musculus 137-141 29260553-3 2018 By controlling conditions of the co-assembly process and employing a carbon-supported thermal treatment strategy, highly ordered mesoporous SnO2 materials with a hexagonal mesostructure (space group P63/mmc) and crystalline pore walls can be obtained. Carbon 69-75 tumor protein p63 Homo sapiens 199-206 29171706-3 2018 Taking CoP nanowire arrays grown on carbon cloth (denoted as CoP NWs/CC) as an example, the oxygen plasma engraving can trigger moderate CoOx species formation on the surface of the CoP NWs/CC, which is visually verified by the X-ray absorption fine structure, high-resolution transmission electron microscopy, and energy-dispersive spectrometer (EDS) mapping. Carbon 36-42 caspase recruitment domain family member 16 Homo sapiens 7-10 29171706-3 2018 Taking CoP nanowire arrays grown on carbon cloth (denoted as CoP NWs/CC) as an example, the oxygen plasma engraving can trigger moderate CoOx species formation on the surface of the CoP NWs/CC, which is visually verified by the X-ray absorption fine structure, high-resolution transmission electron microscopy, and energy-dispersive spectrometer (EDS) mapping. Carbon 36-42 caspase recruitment domain family member 16 Homo sapiens 61-64 29171706-3 2018 Taking CoP nanowire arrays grown on carbon cloth (denoted as CoP NWs/CC) as an example, the oxygen plasma engraving can trigger moderate CoOx species formation on the surface of the CoP NWs/CC, which is visually verified by the X-ray absorption fine structure, high-resolution transmission electron microscopy, and energy-dispersive spectrometer (EDS) mapping. Carbon 36-42 caspase recruitment domain family member 16 Homo sapiens 61-64 29191787-5 2018 In particular, we showed that pyruvate dehydrogenase (PDHA1) enzymatic activity is inhibited by increased phosphorylation in FH-deficient cells, restricting carbon entry from glucose to the tricarboxylic acid cycle. Carbon 157-163 pyruvate dehydrogenase E1 subunit alpha 1 Homo sapiens 54-59 1955379-11 1991 Thus, the fusion of H-271 with C-274 (i.e. CH-271) augments the antimetastatic property of H-271, possibly through the interaction between tumor cells and the heparin-binding domain of fibronectin. Carbon 31-32 fibronectin 1 Mus musculus 185-196 1944177-2 1991 Recently we have applied activated carbon particles to lymph node dissection in the surgery of retroperitoneal neuroblastoma with nodal involvement for the complete resection of this tumor. Carbon 35-41 nodal growth differentiation factor Homo sapiens 130-135 30393650-4 2018 Transmission electron microscopy indicates that there is an approximate 10 nm coating layer with metal zinc and graphite-like carbon on the surface of LFP/CZIF-8 sample. Carbon 126-132 lamin A/C Homo sapiens 151-161 1648005-1 1991 Each strain contains a single, unique base-pair substitution at the Cys-22 codon of the CYC1 gene, which codes for iso-1-cytochrome c. These mutations encode replacements of the functionally critical Cys-22 and render each strain unable to grow on media containing nonfermentable carbon sources (Cyc-). Carbon 280-286 cytochrome c isoform 1 Saccharomyces cerevisiae S288C 88-92 29995566-4 2018 The manipulation of NDPK1 levels in transgenic potato roots demonstrates that this enzyme plays a key role in the transfer of energy between the cytosolic adenine and uridine nucleotide pools and in the distribution of carbon between starch and cellulose. Carbon 219-225 nucleoside diphosphate kinase Solanum tuberosum 20-25 1708392-7 1991 Introduction of the sterol 27-hydroxylase cDNA into Simian COS cells resulted in the expression of active enzyme capable of catalyzing multiple oxidation reactions (R-CH3----R-CH2OH----R-COOH) at carbon 27 of sterol intermediates of the bile acid synthesis pathway. Carbon 196-202 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 20-41 1993694-5 1991 We have found that the ring I vinyl group of the prosthetic heme was altered by the addition of a histidine imidazole nitrogen to the alpha-carbon and a CCl2 moiety to the beta-carbon. Carbon 177-183 C-C motif chemokine ligand 2 Homo sapiens 153-157 29308227-1 2017 Nanocomposite TiO2/ASS (TiO2 nanoparticle coated sewage sludge-based activated carbon) was synthesized by the sol-gel method. Carbon 79-85 argininosuccinate synthase 1 Homo sapiens 14-22 1992118-8 1991 In vitro bioassay data for the gamma-methylene and gamma-cyano compounds support the idea that the active site of DHFR, already known for its ability to tolerate modification of the gamma-carboxyl group of MTX and AMT, can likewise accommodate substitution on the gamma-carbon itself. Carbon 270-276 dihydrofolate reductase Homo sapiens 114-118 1986231-5 1991 Disruption of the MDH2 gene in a haploid yeast strain produced a mutant unable to grow on minimal medium with acetate or ethanol as a carbon source. Carbon 134-140 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 18-22 1986231-6 1991 Disruption of the MDH2 gene in a haploid strain also containing a disruption in the chromosomal MDH1 gene encoding the mitochondrial isozyme produced a strain unable to grow with acetate but capable of growth on rich medium with glycerol as a carbon source. Carbon 243-249 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 18-22 29399410-4 2018 In our experiments, poly(I:C) stimulated expression of both PD-L1 and PD-L2 on glioblastoma cells, and a pro-inflammatory secretome, including type I interferons (IFN) and chemokines CXCL9, CXCL10, CCL4 and CCL5. Carbon 27-28 CD274 molecule Homo sapiens 60-65 2170047-5 1990 We present results indicating that the carboxyl group as well as the four hydroxyl groups at C-2, C-7, C-24 and C-27 of OA are important for activity. Carbon 93-94 complement component 7 Mus musculus 98-101 2685568-7 1989 This carbon source regulation of transcription was found to be mediated, in part, via regulation of RAP1 binding to the AC sequence. Carbon 5-11 DNA-binding transcription factor RAP1 Saccharomyces cerevisiae S288C 100-104 29399410-4 2018 In our experiments, poly(I:C) stimulated expression of both PD-L1 and PD-L2 on glioblastoma cells, and a pro-inflammatory secretome, including type I interferons (IFN) and chemokines CXCL9, CXCL10, CCL4 and CCL5. Carbon 27-28 C-C motif chemokine ligand 4 Homo sapiens 198-202 29964551-7 2017 (3) The characterization of eight carbon fractions percentages in PM2.5 in the different seasons demonstrated similar seasonal variations, with EC1 having the highest percentage and EC3 having the lowest percentage. Carbon 34-40 Susceptibility to lysis by alloreactive natural killer cells Homo sapiens 144-147 2584183-1 1989 Chloroplast-localized NADP-dependent malic enzyme (EC 1.1.1.40) (NADP-ME) provides a key activity for the carbon 4 fixation pathway. Carbon 106-112 NADP-dependent malic enzyme, chloroplastic Zea mays 65-72 2128706-2 1990 Changes in resonances for the carbon-bonded protons of glutathione (GSH) upon addition of the ethylenediaminetetraacetic acid complex of Cd2+ (Cd(EDTA)2-) and the appearance of resonances for Mg(EDTA)2- indicate that the Cd(EDTA)2- complex dissociates in hemolyzed erythrocytes with the formation of Cd(GSH)x and Mg(EDTA)2- complexes. Carbon 30-36 CD2 molecule Homo sapiens 137-140 2261469-4 1990 The localized deshielding at C-13 supports previous models of the opsin shift in rhodopsin that place a protein perturbation in the vicinity of position 13. Carbon 29-30 rhodopsin Bos taurus 81-90 2588307-2 1989 The 13C shielding data of C-7, C-9, and C-19 in both isomers can be used in the determination of the stereochemistry at C-5 of these compounds. Carbon 6-7 complement C7 Homo sapiens 26-34 29212039-4 2017 The model also predicts that the pluripotency factor Lin28 regulates this one-carbon metabolic pathway, which we validate using metabolomics data from Lin28-deficient cells. Carbon 78-84 lin-28 homolog A Mus musculus 53-58 2604948-5 1989 The other methoxyl group has the methyl syn to the neighboring alpha-carbon, with a C-C-O-C torsion angle of -1.3 (3) degrees. Carbon 69-75 synemin Homo sapiens 40-43 2604948-5 1989 The other methoxyl group has the methyl syn to the neighboring alpha-carbon, with a C-C-O-C torsion angle of -1.3 (3) degrees. Carbon 84-85 synemin Homo sapiens 40-43 2604948-5 1989 The other methoxyl group has the methyl syn to the neighboring alpha-carbon, with a C-C-O-C torsion angle of -1.3 (3) degrees. Carbon 86-87 synemin Homo sapiens 40-43 2181283-7 1990 A greater reduction in REB1 activity is observed if the sin3 mutant strain is grown in media containing galactose as a carbon source. Carbon 119-125 DNA-binding protein REB1 Saccharomyces cerevisiae S288C 23-27 29212039-4 2017 The model also predicts that the pluripotency factor Lin28 regulates this one-carbon metabolic pathway, which we validate using metabolomics data from Lin28-deficient cells. Carbon 78-84 lin-28 homolog A Mus musculus 151-156 29200659-5 2017 A miR-21-specific DNA hybridisation probe was immobilised onto a glassy carbon electrode modified by sulfonic acid deposition and subsequent chlorination. Carbon 72-78 microRNA 21 Homo sapiens 2-8 2359386-0 1990 [Extended radical mastectomy using preoperative local injection of activated carbon particle adsorbing aclarubicin (ACR-CH)]. Carbon 77-83 acrosin Homo sapiens 116-119 2683273-1 1989 Cell clones (C-9, C-24, C-36) of the cell line BHK-21 (C-13) were obtained and characterized. Carbon 0-1 complement C9 Homo sapiens 13-16 2683273-1 1989 Cell clones (C-9, C-24, C-36) of the cell line BHK-21 (C-13) were obtained and characterized. Carbon 0-1 homeobox C13 Homo sapiens 55-59 29115125-3 2017 We describe here the preparation and characterization of a hybrid catalyst of Ni2P nanosheets@CoP nanowires on a carbon cloth for the reaction. Carbon 113-119 caspase recruitment domain family member 16 Homo sapiens 94-97 2468308-1 1989 C1-tetrahydrofolate synthase (C1-THF synthase), a eukaryotic trifunctional enzyme, catalyzes three sequential folate-mediated one-carbon interconversions. Carbon 130-136 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Rattus norvegicus 0-28 2468308-1 1989 C1-tetrahydrofolate synthase (C1-THF synthase), a eukaryotic trifunctional enzyme, catalyzes three sequential folate-mediated one-carbon interconversions. Carbon 130-136 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Rattus norvegicus 30-45 2122113-2 1990 Glucose carbon recycling parameters were also derived from 13C NMR spectra of plasma glucose C-1 splitting pattern. Carbon 8-14 heterogeneous nuclear ribonucleoprotein C Homo sapiens 93-96 28830930-6 2017 We found that heme induces transcription of HAP4, the transcriptional activation subunit of the Hap2/3/4/5p complex, required for growth on nonfermentable carbon sources, in a Hap1p- and Hap2/3/4/5p-dependent manner. Carbon 155-161 transcription activator HAP2 Saccharomyces cerevisiae S288C 96-100 2232933-4 1990 Another source of CLA is its endogenous generation via the carbon centered free radical oxidation of linoleic acid. Carbon 59-65 selectin P ligand Homo sapiens 18-21 2676204-1 1989 It was previously observed that increased dosages of the ADR1 gene, which encodes a yeast transcriptional activator required for alcohol dehydrogenase II (ADH II) expression, cause a decreased rate of growth in medium containing ethanol as the carbon source. Carbon 244-250 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 57-61 33825451-0 2021 "Insert-and-Go" Activated Carbon Electrode Tip for Heavy Metal Capture and In Situ Analysis by Microplasma Optical Emission Spectrometry. Carbon 26-32 TOR signaling pathway regulator Homo sapiens 43-46 28936873-8 2017 Finally, the products of Rox(III) degradation were identified as As(III) and 2-nitrohydroquinone, demonstrating that ArsI is a dioxygenase that incorporates one oxygen atom from dioxygen into the carbon and the other to the arsenic to catalyze cleavage of the C-As bond. Carbon 196-202 arylsulfatase family member I Homo sapiens 117-121 33825451-2 2021 Herein, a small activated carbon electrode tip is employed as solid support to preconcentrate heavy metals in water and subsequently served as an inner electrode of the coaxial dielectric barrier discharge (DBD) to generate microplasma. Carbon 26-32 TOR signaling pathway regulator Homo sapiens 43-46 33825451-3 2021 In this case, heavy metal analytes in water are first adsorbed on the surface of the activated carbon electrode tip via a simple liquid-solid phase transformation during the sample loading process, and then, fast released to produce OES during the DBD microplasma excitation process. Carbon 95-101 TOR signaling pathway regulator Homo sapiens 112-115 33825451-5 2021 This activated carbon electrode tip provides a new tool for sample introduction into the DBD microplasma and facilitates "insert-and-go" in subsequent DBD-OES analysis. Carbon 15-21 TOR signaling pathway regulator Homo sapiens 32-35 33825451-6 2021 With a multiplexed activated carbon electrode tip array, a batch of water samples (50 mL) can be loaded in parallel within 5 min. Carbon 29-35 TOR signaling pathway regulator Homo sapiens 10-13 3075657-3 1988 Expression of the whi2 phenotype only occurred above 40% oxygen saturation with either glucose or ethanol as carbon and energy source. Carbon 109-115 Whi2p Saccharomyces cerevisiae S288C 18-22 2836393-7 1988 Mutant strains which lack a functional MIS1 gene are viable and can grow in medium containing a nonfermentable carbon source. Carbon 111-117 trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase MIS1 Saccharomyces cerevisiae S288C 39-43 28849816-5 2017 The HCNCO complex demonstrates a considerable red shift of the H-C stretching vibrations (-24 to -38 cm-1, depending on the matrix) and a blue shift of the HCN bending vibrations (+29 to +32 cm-1) with respect to that of the HCN monomer, while the C[double bond, length as m-dash]O stretching mode is blue-shifted by 15 to 20 cm-1 as compared to the CO monomer. Carbon 5-6 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 156-159 3290644-3 1988 ADR1 mRNA levels were regulated by the carbon source in a strain-dependent fashion. Carbon 39-45 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 0-4 33813652-0 2021 Effect of confinement of horse heart cytochrome c and formate dehydrogenase from Candida boidinii on mesoporous carbons on their catalytic activity. Carbon 112-119 cytochrome c, somatic Equus caballus 37-49 33801464-6 2021 Furthermore, SARS-CoV-2 N inhibited polyinosinic: polycytidylic acid [poly(I:C)]-mediated IFN signaling at the level of Tank-binding kinase 1 (TBK1) and interfered with the association between TBK1 and interferon regulatory factor 3 (IRF3), subsequently preventing the nuclear translocation of IRF3. Carbon 77-79 nucleocapsid phosphoprotein Severe acute respiratory syndrome coronavirus 2 24-25 33801464-6 2021 Furthermore, SARS-CoV-2 N inhibited polyinosinic: polycytidylic acid [poly(I:C)]-mediated IFN signaling at the level of Tank-binding kinase 1 (TBK1) and interfered with the association between TBK1 and interferon regulatory factor 3 (IRF3), subsequently preventing the nuclear translocation of IRF3. Carbon 77-79 TANK binding kinase 1 Homo sapiens 143-147 3442668-7 1987 The kinetic constants for the adenosine deaminase catalyzed hydrolysis of 6-chloro- and 6-fluoropurine riboside have been compared, and the reactivity order implies that carbon-halogen bond breaking does not occur in the rate-determining step. Carbon 170-176 adenosine deaminase Homo sapiens 30-49 28647381-8 2017 Montelukast significantly attenuated the poly I:C-induced increase in the number of eosinophils and levels of IL-13, IL-9, and CCL3 in BALF and airway hyperresponsiveness in both the reliever and controller models. Carbon 48-49 chemokine (C-C motif) ligand 3 Mus musculus 127-131 3425914-1 1987 The reaction of four to eight carbon straight-chain alk-2-enals with 2-thiobarbituric acid (TBA) produced yellow 455-nm-, orange 495-nm-, and red 532-nm-absorbing pigments depending upon the reaction conditions. Carbon 30-36 activin A receptor type 1 Homo sapiens 52-57 33972848-1 2021 This research involved carrying out a unique micro-mesoporous carbon particle incorporation into P84 co-polyimide membrane for improved gas separation performance. Carbon 62-68 gastrin Homo sapiens 136-139 27856334-7 2017 CTP-deficient cells displayed a major restructuring of central carbon metabolism, including suppression of pyruvate dehydrogenase (PDH) and induction of glucose-dependent anaplerosis through pyruvate carboxylase (PC). Carbon 63-69 solute carrier family 25 member 1 Homo sapiens 0-3 33237088-0 2020 CoP and Ni2P implanted in a hollow porous N-doped carbon polyhedron for pH universal hydrogen evolution reaction and alkaline overall water splitting. Carbon 50-56 caspase recruitment domain family member 16 Homo sapiens 0-3 33237088-2 2020 Herein, a novel bifunctional electrocatalyst composed of CoP and Ni2P nanoparticles implanted in a hollow porous N-doped carbon polyhedron (CoP/Ni2P@HPNCP) is synthesized by carbonization of Co/Ni-layered double hydroxide@zeolitic imidazolate framework-67 (Co/Ni-LDH@ZIF-67) followed by an oxidation and phosphorization strategy. Carbon 121-127 caspase recruitment domain family member 16 Homo sapiens 57-60 3313003-3 1987 In contrast, ENO2 expression is induced more than 20-fold in cells grown on glucose as the carbon source. Carbon 91-97 phosphopyruvate hydratase ENO2 Saccharomyces cerevisiae S288C 13-17 3571285-7 1987 The amount of methylenetetrahydrofolate consumed was equal to that of methylene carbon attached to H-protein. Carbon 80-86 myosin binding protein H Homo sapiens 99-108 27856334-8 2017 We also observed an unusual lipogenic pathway in which carbon from glucose supplies mitochondrial production of alpha-ketoglutarate (AKG), which is then trafficked to the cytosol and used to supply reductive carboxylation by isocitrate dehydrogenase 1 (IDH1). Carbon 55-61 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 225-251 27856334-8 2017 We also observed an unusual lipogenic pathway in which carbon from glucose supplies mitochondrial production of alpha-ketoglutarate (AKG), which is then trafficked to the cytosol and used to supply reductive carboxylation by isocitrate dehydrogenase 1 (IDH1). Carbon 55-61 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 253-257 33034509-4 2020 Normal early neural differentiation depends crucially on folic acid (FA) and methionine (MET), both elements of the one-carbon (1C) cycle. Carbon 120-126 SAFB like transcription modulator Homo sapiens 89-92 28796474-3 2017 During the fabrication process, Co, S co-doped graphitic carbon nitride (g-C3N4) was first produced, and then this in-situ-formed template further induced the generation of a Co, N, S tri-doped graphene coupled with Co nanoparticles (NPs) in the following pyrolysis process. Carbon 47-56 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 66-69 34991009-3 2022 Orange-red emissive carbon dots (OR-CDs), prepared from the calcination of selected carbon sources 5-amino-1, 10-phenanthroline (Aphen) and salicylic acid (SA), were found to act as a "turn on" type fluorescence probe for Cd2+ detection. Carbon 20-26 CD2 molecule Homo sapiens 222-225 34991009-3 2022 Orange-red emissive carbon dots (OR-CDs), prepared from the calcination of selected carbon sources 5-amino-1, 10-phenanthroline (Aphen) and salicylic acid (SA), were found to act as a "turn on" type fluorescence probe for Cd2+ detection. Carbon 84-90 CD2 molecule Homo sapiens 222-225 3103677-0 1987 Paramagnetic carbon-13 NMR relaxation studies on the kinetics and mechanism of the HCO3-/CO2 exchange catalyzed by manganese(II) human carbonic anhydrase I. Carbon 13-19 carbonic anhydrase 1 Homo sapiens 135-155 3098173-4 1986 The results presented in this paper indicate that the decarboxylation is not accompanied by the removal of a C-2 hydrogen atom of glycine and instead both C-2 hydrogens are transferred with the alpha carbon atom to the intermediate formed during the decarboxylation of glycine. Carbon 200-206 complement C2 Bos taurus 155-158 28692195-3 2017 Iron-doped cobalt phosphate borate nanoarray on carbon cloth (Fe-Co-Pi-Bi/CC) derived from iron-doped cobalt phosphide on CC (Fe-CoP/CC) through oxidative polarization behaves as a highly active bimetallic electrocatalyst for water oxidation with an overpotential of 382 mV to afford a catalytic current density of 10 mA cm-2 in 0.1 m potassium borate (K-Bi, pH 9.2). Carbon 48-54 caspase recruitment domain family member 16 Homo sapiens 129-132 3531058-6 1986 For inactivation of rad54-3 mutant cells, the r.b.e.-values relative to 60Co gamma-rays were 2.6 and 2.4 for carbon K and aluminium K X-rays, respectively. Carbon 109-115 DNA-dependent ATPase RAD54 Saccharomyces cerevisiae S288C 20-25 34893304-4 2022 For some less active epoxides with steric hindrance, Ar-G-CM/SiO2 also showed good yield and selectivity over 90% by raising temperature to 120 C. Furthermore, the Ar-G-CM/SiO2 catalyst could be reused for six successive cycles without significant decrease in catalytic activity or structural deterioration, because the carbon deposition was restrained owing to the mesoporous structure of the catalyst. Carbon 321-327 ABL proto-oncogene 2, non-receptor tyrosine kinase Homo sapiens 53-57 34893304-4 2022 For some less active epoxides with steric hindrance, Ar-G-CM/SiO2 also showed good yield and selectivity over 90% by raising temperature to 120 C. Furthermore, the Ar-G-CM/SiO2 catalyst could be reused for six successive cycles without significant decrease in catalytic activity or structural deterioration, because the carbon deposition was restrained owing to the mesoporous structure of the catalyst. Carbon 321-327 ABL proto-oncogene 2, non-receptor tyrosine kinase Homo sapiens 165-169 34624764-0 2022 n-type absorber by Cd2+ doping achieves high-performance carbon-based CsPbIBr2 perovskite solar cells. Carbon 57-63 CD2 molecule Homo sapiens 19-22 34624764-6 2022 The corresponding carbon-based all-inorganic Cd2+-doped CsPbIBr2 PSCs achieve a maximum PCE of 10.63% with a high open circuit voltage (VOC) of 1.324 V, which are much higher than those of the control one with a PCE of 8.48% and an VOC of 1.235 V. The unencapsulated device can still retain more than 92% of the initial PCE when stored at ambient atmosphere (25 C, relative humidity about 30%) for 40 days. Carbon 18-24 CD2 molecule Homo sapiens 45-48 28827554-5 2017 We investigate individual Co2FeGa Heusler nanoparticles with diameters of the order of 35 nm encapsulated in carbon nanotubes. Carbon 109-115 complement C2 Homo sapiens 26-29 34608726-3 2022 Herein, we develop an atomically dispersed monovalent zinc anchored on nitrogenated carbon nanosheets (Zn/NC NSs) as an efficient catalyst for CO2RR. Carbon 84-90 complement C2 Homo sapiens 143-148 34742147-4 2022 When the background gas is pure nitrogen and a mixture of nitrogen and carbon dioxide, the recovery effect of this method on methane is both close to the theoretical value when the background gas is air. Carbon 71-77 gastrin Homo sapiens 20-23 24232139-0 1986 Carbon and nitrogen metabolism in barley (Hordeum vulgare L.) mutants lacking ferredoxin-dependent glutamate synthase. Carbon 0-6 ferredoxin-dependent glutamate synthase, Fd-GOGAT Hordeum vulgare 78-117 3954792-0 1986 Stereospecific deuterium substitution at the alpha-carbon position of dopamine and its effect on oxidative deamination catalyzed by MAO-A and MAO-B from different tissues. Carbon 51-57 monoamine oxidase B Homo sapiens 142-147 28528194-2 2017 In this study, a liquid chromatography-.high resolution mass spectrometry (LC-HRMS) method was established for the analysis of PEG oligomers in carbon-based black gel ink entries. Carbon 144-150 progestagen associated endometrial protein Homo sapiens 127-130 3004337-2 1986 Tissue extracts of mice given an intraperitoneal or intragastric dose of the spin trap, alpha-phenyl-t-butyl nitrone prior to exposure to gamma radiation (2 to 5 Gy), contained a radical adduct with hyperfine splitting constants characteristic of spin adducts of carbon-centered lipid radicals. Carbon 263-269 spindlin 1 Mus musculus 77-81 3866515-0 1985 Protein synthesis by mammalian cells treated with C-3-modified analogs of the 12,13-epoxytrichothecenes T-2 and T-2 tetraol. Carbon 50-51 solute carrier family 25 member 5 Homo sapiens 104-107 34783135-3 2022 By taking ultrathin in-plane Cu 2 O/Cu heterostructures as a prototype, we show that Lewis acid-base sites on heterointerface can facilitate a mixed C and O dual coordination on surface, which not only strengthen CO 2 adsorption, but also effectively activate the inert molecules. Carbon 149-150 complement C2 Homo sapiens 213-217 28639182-0 2017 Differential Interaction of Myoglobin with Select Fatty Acids of Carbon Chain Lengths C8 to C16. Carbon 65-71 myoglobin Homo sapiens 28-37 34863066-6 2022 PPAR transactivation activity demonstrated that the seven-carbon side chain analogs (series 1) displayed selectivity for hPPARalpha, while the nine-carbon side chain analogs (polycerasoidol analogs, series 2) did so for hPPARgamma. Carbon 58-64 peroxisome proliferator activated receptor alpha Homo sapiens 121-131 34619534-0 2022 Transcriptomic evidences for microbial carbon and nitrogen cycles in the deoxygenated seawaters of Bohai Sea. Carbon 39-45 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 105-108 3906028-2 1985 Variations in the amounts of these enzymes in cells growing on glucose and on ethanol showed that hexokinase PI was a constitutive enzyme, whereas synthesis of hexokinase PII and glucokinase were regulated by the carbon source used. Carbon 213-219 glucokinase Saccharomyces cerevisiae S288C 179-190 6508285-5 1984 To convert bacterial biovolume into biomass (carbon content), we suggest that 0.22 g of C cm-3 should be used as a conversion factor. Carbon 45-51 programmed cell death 10 Homo sapiens 88-94 28531970-3 2017 In this work, a simple and ultrasensitive cholesterol biosensor based on enzymatic silver deposition was designed by immobilizing cholesterol oxidase (CHOD) and cholesterol esterase (CHER) onto the surface of gold nanoparticles (Au NPs) modified screen-printed carbon electrode (SPE). Carbon 261-267 carboxyl ester lipase Homo sapiens 183-187 6375666-2 1984 Substitution of deuterium for hydrogen at the terminal carbon atoms (C-3) of Tris-BP significantly decreased both the mutagenic response and the formation rate of 2- bromoacrolein . Carbon 55-61 complement C3 Homo sapiens 69-72 34342829-4 2022 Upon deposition as thin film on a glassy carbon electrode (GCE), the ion exchange ability of NHAPp0.5-CA-beta-CD was exploited to elaborate a sensitive sensor for the detection of lead. Carbon 41-47 ACD shelterin complex subunit and telomerase recruitment factor Bos taurus 105-112 34704324-3 2021 Fe single atoms dispersed in hierarchically porous N-doped carbon matrix with high metal content (2.78 wt.%) and configuration of FeN4Cl1 (FeN4Cl1/NC) as well as mesopores with proportion of 0.92 (pore-volume ration) were obtained via the pyrolysis of a Zn/Fe-bimetallic MET modified with 4,5-dichloroimidazole. Carbon 59-65 SAFB like transcription modulator Homo sapiens 271-274 34947482-1 2021 This article studied the effects of pin angle on heat generation and temperature distribution during friction stir welding (FSW) of AA1100 aluminum alloy and St-14 low carbon steel. Carbon 168-174 ST14 transmembrane serine protease matriptase Homo sapiens 158-163 34949739-4 2022 We showed that LPS/zVAD- and poly I:C/zVAD-induced cell death in bone marrow-derived macrophages (BMDMs) was inhibited by receptor-interacting protein kinase 1 (RIP1) inhibitor necrostatin-1 and autophagy inhibitor 3-methyladenine. Carbon 36-37 receptor interacting serine/threonine kinase 1 Homo sapiens 122-159 34949739-4 2022 We showed that LPS/zVAD- and poly I:C/zVAD-induced cell death in bone marrow-derived macrophages (BMDMs) was inhibited by receptor-interacting protein kinase 1 (RIP1) inhibitor necrostatin-1 and autophagy inhibitor 3-methyladenine. Carbon 36-37 receptor interacting serine/threonine kinase 1 Homo sapiens 161-165 6692496-4 1984 Significant changes in many of the carbon resonances of the adducts are observed suggesting three general conformational changes, namely: (1) chemical shift changes are noted in base carbon atom resonances as a function of temperature and adduct formation which are indicative of stacking effects; (2) large upfield shifts of the furanose C2" resonance of the guanosine-adduct indicate a shift to higher populations of the syn conformation. Carbon 183-189 synemin Homo sapiens 423-426 28627074-1 2017 A transition-metal-nitrogen/carbon (TM-N/C, TM = Fe, Co, Ni, etc.) Carbon 28-34 STT3 oligosaccharyltransferase complex catalytic subunit A Homo sapiens 36-42 6468742-4 1984 A comparison of the incorporation of labeled carbon from [1-14C]palmitate and [U-14C]palmitate into glucose and CO2 indicates a selective stimulatory action of glucagon on the flux through the phosphoenolpyruvate carboxykinase (PEPCK) reaction. Carbon 45-51 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 193-226 30023691-4 2017 The FAA1 and FAA4 genes encoding two acyl-CoA synthetases in S. cerevisiae were deleted, resulting in the accumulation of FFAs with carbon chain length from C8 to C18. Carbon 132-138 long-chain fatty acid-CoA ligase FAA1 Saccharomyces cerevisiae S288C 4-8 24264539-7 1983 Incubation of an equimolar mixture of homologous saturated rac-1-O-[1"(14)C]alkylglycerols (C14, C16, C18, C20) with rape cells showed that alkylglycerols with alkyl moieties having 16 and 18 carbon atoms were incorporated preferentially. Carbon 192-198 Rac family small GTPase 1 Homo sapiens 59-64 34943254-10 2021 This small United Kingdom Overseas Territory"s reef systems represent approximately 0.8 Mt CO2 equivalent sequestered carbon; valued at >$24 Million GBP (at the UN shadow price of carbon). Carbon 118-124 transmembrane protein 132A Homo sapiens 149-152 34265689-3 2021 Herein, we designed N-doped carbon restricted CoP polyhedra embedded into reduced graphene oxide (rGO) sheet (CoP/NC@rGO) through coupling the function of ZIF-67 and rGO. Carbon 28-34 caspase recruitment domain family member 16 Homo sapiens 46-49 34265689-3 2021 Herein, we designed N-doped carbon restricted CoP polyhedra embedded into reduced graphene oxide (rGO) sheet (CoP/NC@rGO) through coupling the function of ZIF-67 and rGO. Carbon 28-34 caspase recruitment domain family member 16 Homo sapiens 110-113 6852253-1 1983 The proton NMR analysis of D-glucosaminate dehydratase reaction in D2O revealed the incorporation of a deuterium atom at C-3 carbon of the product, 2-keto-3-deoxy-D-gluconate. Carbon 125-131 complement C3 Homo sapiens 121-124 6852253-3 1983 Thus, the dehydration of D-glucosaminate by the enzyme proceeds in a retention mode at C-3 carbon. Carbon 91-97 complement C3 Homo sapiens 87-90 34265689-4 2021 For this composite, nano-scale CoP particles can be encapsulated by ZIF-67 derived carbon matrix, which significantly alleviates the volume change and promotes K+/e- transfer. Carbon 83-89 caspase recruitment domain family member 16 Homo sapiens 31-34 30023691-4 2017 The FAA1 and FAA4 genes encoding two acyl-CoA synthetases in S. cerevisiae were deleted, resulting in the accumulation of FFAs with carbon chain length from C8 to C18. Carbon 132-138 long-chain fatty acid-CoA ligase FAA4 Saccharomyces cerevisiae S288C 13-17 6551234-3 1983 The correlation times of carbonyl carbons of the elastin backbone show that elastin chains are very flexible at the molecular level. Carbon 34-41 elastin Homo sapiens 49-56 6551234-3 1983 The correlation times of carbonyl carbons of the elastin backbone show that elastin chains are very flexible at the molecular level. Carbon 34-41 elastin Homo sapiens 76-83 28475227-3 2017 However, it was recently reported that high-temperature carbon-reactor methods for measuring the hydrogen isotopic composition of nitrogenous organic materials is biased by the production of HCN in the reactor. Carbon 56-62 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 191-194 6816782-13 1982 The combination of Lys + C further increased (P less than .05) the ADG over that of the high protein sequence group. Carbon 25-26 ADG Sus scrofa 67-70 34911949-0 2021 Sea-ice derived meltwater stratification slows the biological carbon pump: results from continuous observations. Carbon 62-68 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 0-3 34911949-2 2021 The North Atlantic Ocean west (Baffin Bay/Labrador Sea) and east (Fram Strait/Greenland Sea) of Greenland features the most intense absorption of anthropogenic carbon globally; the biological carbon pump (BCP) contributes substantially. Carbon 160-166 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 51-54 34911949-2 2021 The North Atlantic Ocean west (Baffin Bay/Labrador Sea) and east (Fram Strait/Greenland Sea) of Greenland features the most intense absorption of anthropogenic carbon globally; the biological carbon pump (BCP) contributes substantially. Carbon 160-166 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 88-91 28676645-10 2017 Moreover, KIF5A was notably upregulated along with Col-1 and alpha-smooth muscle actin in pleural thickening in the carbon-black bleomycin mouse model. Carbon 116-122 kinesin family member 5A Mus musculus 10-15 34519404-4 2021 Scanning tunneling spectroscopy (STS) characterizations reveal that NBN-BT (3.08 eV) and NBN-PT ( 3.28 eV) possess higher energy gaps than their carbon-based bis -tetracene (1.56 eV) and peri -tetracene (1.11 eV) analogs. Carbon 145-152 nibrin Homo sapiens 89-92 34519404-8 2021 This work provides a novel synthesis along with characterizations of multi-NBN-doped zigzag-edged peri -acenes with tunable electronic properties that are not accessible with classical all-carbon-based peri -acenes. Carbon 189-195 nibrin Homo sapiens 75-78 6288103-2 1982 90% of the variants selected for their ability to use D-ribose as a sole carbon source show a change in ribokinase activity. Carbon 73-79 ribokinase Rattus norvegicus 104-114 6288103-4 1982 In the variants, ribokinase expression in non-inducible by the carbon source and is unaffected by the growth phase of the cells. Carbon 63-69 ribokinase Rattus norvegicus 17-27 34753571-0 2021 Fluorescence turn-on immunosensing of HE4 biomarker and ovarian cancer cells based on target-triggered metal-enhanced fluorescence of carbon dots. Carbon 134-140 WAP four-disulfide core domain 2 Homo sapiens 38-41 28656558-8 2017 Organic carbon increased the sensor nitrate plus nitrite results, not only in waters with high organic carbon concentrations, but also at the lower concentrations (< 10 mg C L-1) typical of boreal stream, river, and lake waters. Carbon 8-14 adhesion G protein-coupled receptor L1 Homo sapiens 175-180 34399167-2 2021 Herein, we developed a novel kind of electrochemical microRNA biosensor based on two-dimensional nanomaterial of antimonene nano-flakes (AMNFs) and carbon quantum dots (CQDs) which were used as substrating to cadmium ion (Cd2+) for specific detection of breast cancer-relevant biomarker-microRNA-21. Carbon 148-154 CD2 molecule Homo sapiens 222-225 34399167-2 2021 Herein, we developed a novel kind of electrochemical microRNA biosensor based on two-dimensional nanomaterial of antimonene nano-flakes (AMNFs) and carbon quantum dots (CQDs) which were used as substrating to cadmium ion (Cd2+) for specific detection of breast cancer-relevant biomarker-microRNA-21. Carbon 148-154 microRNA 21 Homo sapiens 287-298 27519606-6 1982 Reduction of the C-24(28) double bond make take place after all the functional groups have been introduced, at C7, C-11 and C-15, in the tetracyclic structure. Carbon 17-18 RNA polymerase III subunit K Homo sapiens 115-119 27519606-6 1982 Reduction of the C-24(28) double bond make take place after all the functional groups have been introduced, at C7, C-11 and C-15, in the tetracyclic structure. Carbon 17-18 placenta associated 8 Homo sapiens 124-128 27957768-1 2017 Here, we studied the influence of the methoxyl groups attached at C-7 and C-2" of natural and synthetic 1-arylindanes on the chemical shift of the signal of bibenzylic hydrogen and carbon atoms and J1,2 coupling constants. Carbon 181-187 complement C2 Homo sapiens 74-77 34668589-6 2021 Carbon SOBP measurements behind lung substitute material were performed to validate the code. Carbon 0-6 sine oculis binding protein homolog Homo sapiens 7-11 34741432-2 2021 Herein, a sea urchin-shaped cobalt-embedded N-doped carbon nanotubes (Co@NCNT) encapsulated CoPt3 @Co2 P heterojunction (CoPt3 @Co2 P/Co@NCNT) is fabricated. Carbon 52-58 complement C2 Homo sapiens 99-102 28625755-8 2017 The investigation of other non-intuitive interventions like the deletion of the Pho13 enzyme also revealed the important role of the transaldolase in determining the fate of the carbon flux in the pathways of study. Carbon 178-184 4-nitrophenylphosphatase Saccharomyces cerevisiae S288C 80-85 34741432-2 2021 Herein, a sea urchin-shaped cobalt-embedded N-doped carbon nanotubes (Co@NCNT) encapsulated CoPt3 @Co2 P heterojunction (CoPt3 @Co2 P/Co@NCNT) is fabricated. Carbon 52-58 complement C2 Homo sapiens 128-131 34741432-5 2021 Moreover, the electrolyzer employing CoPt3 @Co2 P/Co@NCNT for anodic MOR and cathodic H2 production only requires a low voltage of 1.43 V at 10 mA cm-2 with impressive long-life cycling stability, which is obviously better than that of commercial Pt/C//RuO2 . Carbon 250-251 complement C2 Homo sapiens 44-47 28544389-2 2017 A unique ball-cactus-like microsphere of carbon coated NiP2 /Ni3 Sn4 with deep-rooted carbon nanotubes (Ni-Sn-P@C-CNT) is demonstrated in this work to solve this problem. Carbon 41-47 BCL2 interacting protein 2 Homo sapiens 55-59 34664574-2 2021 Phosphonium ylides representing another class of neutral eta1-bonded carbon ligands have also been shown to act as effective Lewis bases. Carbon 69-75 secreted phosphoprotein 1 Homo sapiens 57-61 28544389-2 2017 A unique ball-cactus-like microsphere of carbon coated NiP2 /Ni3 Sn4 with deep-rooted carbon nanotubes (Ni-Sn-P@C-CNT) is demonstrated in this work to solve this problem. Carbon 86-92 BCL2 interacting protein 2 Homo sapiens 55-59 34835803-0 2021 Tunable Low Crystallinity Carbon Nanotubes/Silicon Schottky Junction Arrays and Their Potential Application for Gas Sensing. Carbon 26-32 gastrin Homo sapiens 112-115 28544389-2 2017 A unique ball-cactus-like microsphere of carbon coated NiP2 /Ni3 Sn4 with deep-rooted carbon nanotubes (Ni-Sn-P@C-CNT) is demonstrated in this work to solve this problem. Carbon 112-113 BCL2 interacting protein 2 Homo sapiens 55-59 28840693-3 2017 All the tested compounds made the expression of the target gene NDUFV2 decreased on human hepatic carcinoma cell line SMMC-7721/ADR, of which the bistetrahydrofuran ACGs showed the best activity,which the non-adjacent bistetrahydrofuran ACGs displayed the worst activity.The ACGs with the reducing number of carbons between gamma-unsaturated lactone and the close tetrahydrofuran (THF) ring are more potent. Carbon 308-315 NADH:ubiquinone oxidoreductase core subunit V2 Homo sapiens 64-70 28604855-1 2017 A novel P(NMe2)3-mediated formal carbon-halogen bond insertion of isatins into allylic and benzylic bromides/chlorides has been realized, leading to a facile synthesis of 3-halo 3,3"-disubstituted oxindoles. Carbon 33-39 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 10-14 34977899-3 2021 The resulting TTF/TTF +@carbon junction (TTF = tetrathiafulvalene) acts as an all-in-one highly stable redox-shuttle/photosensitizer/molecular-catalyst triad for the visible-light-driven water oxidation reaction (WOR) at neutral pH, eliminating the need for metallic or organometallic catalysts and sacrificial electron acceptors. Carbon 24-30 ras homolog family member H Homo sapiens 14-17 34977899-3 2021 The resulting TTF/TTF +@carbon junction (TTF = tetrathiafulvalene) acts as an all-in-one highly stable redox-shuttle/photosensitizer/molecular-catalyst triad for the visible-light-driven water oxidation reaction (WOR) at neutral pH, eliminating the need for metallic or organometallic catalysts and sacrificial electron acceptors. Carbon 24-30 ras homolog family member H Homo sapiens 18-21 34977899-3 2021 The resulting TTF/TTF +@carbon junction (TTF = tetrathiafulvalene) acts as an all-in-one highly stable redox-shuttle/photosensitizer/molecular-catalyst triad for the visible-light-driven water oxidation reaction (WOR) at neutral pH, eliminating the need for metallic or organometallic catalysts and sacrificial electron acceptors. Carbon 24-30 ras homolog family member H Homo sapiens 41-44 34977899-4 2021 A water/butyronitrile emulsion was used to physically separate the photoproducts of the WOR, H+ and TTF, allowing the extraction and subsequent reduction of protons in water, and the in situ electrochemical oxidation of TTF to TTF + on carbon in butyronitrile by constant anode potential electrolysis. Carbon 236-242 ras homolog family member H Homo sapiens 220-223 28530824-0 2017 Human Immune Protein C1q Selectively Disaggregates Carbon Nanotubes. Carbon 51-57 complement C1q A chain Homo sapiens 21-24 34977899-4 2021 A water/butyronitrile emulsion was used to physically separate the photoproducts of the WOR, H+ and TTF, allowing the extraction and subsequent reduction of protons in water, and the in situ electrochemical oxidation of TTF to TTF + on carbon in butyronitrile by constant anode potential electrolysis. Carbon 236-242 ras homolog family member H Homo sapiens 227-230 28530824-1 2017 We atomistically compute the change in free energy upon binding of the globular domain of the complement protein C1q to carbon nanotubes (CNTs) and graphene in solution. Carbon 120-126 complement C1q A chain Homo sapiens 113-116 34156620-6 2021 The findings reveal that renewable energy consumption and environmental quality, i.e. lesser carbon emissions, enhance subjective wellbeing in G20 countries. Carbon 93-99 chromosome 3 open reading frame 18 Homo sapiens 143-146 28564604-4 2017 On a molecular level, diminished IDH1 activity results in reduced alpha-ketoglutarate (alphaKG) and NADPH production, paralleled by deficient carbon flux from glucose or acetate into lipids, exhaustion of reduced glutathione, increased levels of reactive oxygen species (ROS), and enhanced histone methylation and differentiation marker expression. Carbon 142-148 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 33-37 34487922-3 2021 Meanwhile, the oxidation of C-18 methyl to carboxyl group forms a 18,20-lactone, and the oxidation of C-14 and C-17 gets a heterocyclic oxygen acrossing rings C and D. Additionly, physalins frequently form an oxygen bridge to connect C-14 to C-27. Carbon 102-103 cytokine like 1 Homo sapiens 111-115 28481553-3 2017 The tandem reaction proceeds in the presence of BCl3 to generate three new carbon-carbon bonds, a quaternary carbon, and two stereogenic centers with excellent diastereocontrol. Carbon 75-81 BCL3 transcription coactivator Homo sapiens 48-52 34487922-3 2021 Meanwhile, the oxidation of C-18 methyl to carboxyl group forms a 18,20-lactone, and the oxidation of C-14 and C-17 gets a heterocyclic oxygen acrossing rings C and D. Additionly, physalins frequently form an oxygen bridge to connect C-14 to C-27. Carbon 234-235 cytokine like 1 Homo sapiens 111-115 34487922-3 2021 Meanwhile, the oxidation of C-18 methyl to carboxyl group forms a 18,20-lactone, and the oxidation of C-14 and C-17 gets a heterocyclic oxygen acrossing rings C and D. Additionly, physalins frequently form an oxygen bridge to connect C-14 to C-27. Carbon 242-243 cytokine like 1 Homo sapiens 111-115 34714616-6 2021 Further, we exemplify the validity of our calculations by comparing the simulated Ragone plot with that of a Na-HIC fabricated using in-house-made carbon. Carbon 147-153 MyoD family inhibitor domain containing Homo sapiens 112-115 34716815-0 2021 Carbon nanodot-based electrogenerated chemiluminescence biosensor for miRNA-21 detection. Carbon 0-6 microRNA 21 Homo sapiens 70-78 28481553-3 2017 The tandem reaction proceeds in the presence of BCl3 to generate three new carbon-carbon bonds, a quaternary carbon, and two stereogenic centers with excellent diastereocontrol. Carbon 82-88 BCL3 transcription coactivator Homo sapiens 48-52 34716815-1 2021 A simple carbon nanodot-based electrogenerated chemiluminescence biosensor is described for sensitive and selective detection of microRNA-21 (miRNA-21), a biomarker of several pathologies including cardiovascular diseases (CVDs). Carbon 9-15 microRNA 21 Homo sapiens 129-140 28481553-3 2017 The tandem reaction proceeds in the presence of BCl3 to generate three new carbon-carbon bonds, a quaternary carbon, and two stereogenic centers with excellent diastereocontrol. Carbon 82-88 BCL3 transcription coactivator Homo sapiens 48-52 34716815-1 2021 A simple carbon nanodot-based electrogenerated chemiluminescence biosensor is described for sensitive and selective detection of microRNA-21 (miRNA-21), a biomarker of several pathologies including cardiovascular diseases (CVDs). Carbon 9-15 microRNA 21 Homo sapiens 142-150 28056439-3 2017 Screen-printed carbon sensors coated with electrochemically reduced graphene oxide (ERGO) and a second set of antibodies selectively capture the biomarker-laden Fe3O4@GO particles, which subsequently catalyze hydrogen peroxide reduction to detect PSA and PSMA. Carbon 15-21 kallikrein related peptidase 3 Homo sapiens 247-250 34708601-0 2021 (MIXed plastics biodegradation and UPcycling using microbial communities: the NSFC-EU 2019 project MIX-UP to help achieve "carbon neutrality"). Carbon 123-129 Mix paired-like homeobox Homo sapiens 99-102 34708601-6 2021 Through NSFC-EU complementary and cross-disciplinary cooperation, MIX-UP proposes the engineering of a new-to-nature biological route for upcycling, a low carbon and sustainable bio-treatment that is different from the traditional physico-chemical treatment, which will empower the recycling industry to a new dimension. Carbon 155-161 Mix paired-like homeobox Homo sapiens 66-69 28440366-0 2017 Improved electrical conductivity of TPU/carbon black composites by addition of COPA and selective localization of carbon black at the interface of sea-island structured polymer blends. Carbon 40-46 COPI coat complex subunit alpha Homo sapiens 79-83 34657897-2 2021 It adsorbs toxic gaseous matters onto the surface of various granular adsorbents, such as silica gel or activated carbon packed in a thin glass tube, for quantitative analysis by gas chromatography. Carbon 114-120 gastrin Homo sapiens 179-182 34676016-1 2021 The electrosorption of Gd3+ ions from an aqueous 70 mM Gd(NO3)3 solution in monolithic carbon aerogel electrodes was recorded by dynamic neutron imaging. Carbon 87-93 GRDX Homo sapiens 23-26 28128526-2 2017 Previously, we have shown that multiwalled carbon nanotubes (MWCNT) regulate ECM components TGFbeta and its target Col3A1 in alveolar epithelial cells. Carbon 43-49 collagen type III alpha 1 chain Homo sapiens 115-121 28213255-1 2017 We report a novel amperometric glucose biosensor based on glucose oxidase (GOx) immobilized on a carbon nanotube (CNTs)-poly(diallyldimethyl-ammonium chloride) (PDDA)-platinum nanoparticle (PtNPs) modified carbon-paste electrode (CNTs-PDDA-PtNPs/CPE). Carbon 97-103 carboxypeptidase E Homo sapiens 246-249 34348966-5 2021 PCK1 subsequently triggered retrograde carbon flow from gluconeogenesis to glycogenesis, glycogenolysis, and the pentose phosphate pathway. Carbon 39-45 phosphoenolpyruvate carboxykinase 1 Homo sapiens 0-4 28213257-1 2017 A high-surface-area nanoporous carbon (NPC) has been successfully synthesized by using the metal-organic framework ZIF-90 as both the template and precursor together with furfuryl alcohol as a secondary carbon source. Carbon 31-37 NPC intracellular cholesterol transporter 1 Homo sapiens 39-42 28213257-1 2017 A high-surface-area nanoporous carbon (NPC) has been successfully synthesized by using the metal-organic framework ZIF-90 as both the template and precursor together with furfuryl alcohol as a secondary carbon source. Carbon 203-209 NPC intracellular cholesterol transporter 1 Homo sapiens 39-42 34677521-1 2021 Gas separation is of significant importance for many industrial processes including chemical purification, carbon capture, and fuel production (...). Carbon 107-113 gastrin Homo sapiens 0-3 28351640-3 2017 To decrease the background signal, monoclonal anti-human PSA capture antibody was covalently conjugated onto an activated glassy carbon electrode via typical carbodiimide coupling. Carbon 129-135 kallikrein related peptidase 3 Homo sapiens 57-60 34638851-0 2021 State of the Art in the Antibacterial and Antiviral Applications of Carbon-Based Polymeric Nanocomposites. Carbon 68-74 artemin Homo sapiens 13-16 28323408-0 2017 Monodispersed Carbon-Coated Cubic NiP2 Nanoparticles Anchored on Carbon Nanotubes as Ultra-Long-Life Anodes for Reversible Lithium Storage. Carbon 14-20 BCL2 interacting protein 2 Homo sapiens 34-38 34677453-5 2021 The branches consisting of beta-d-Galp-(1 and 6)-beta-d-Galp-(1 units were located in C-3 of 6)-beta-d-Galp-(1 units. Carbon 89-91 galanin like peptide Homo sapiens 34-38 34677453-5 2021 The branches consisting of beta-d-Galp-(1 and 6)-beta-d-Galp-(1 units were located in C-3 of 6)-beta-d-Galp-(1 units. Carbon 89-91 galanin like peptide Homo sapiens 58-62 34677453-5 2021 The branches consisting of beta-d-Galp-(1 and 6)-beta-d-Galp-(1 units were located in C-3 of 6)-beta-d-Galp-(1 units. Carbon 89-91 galanin like peptide Homo sapiens 107-111 28323408-0 2017 Monodispersed Carbon-Coated Cubic NiP2 Nanoparticles Anchored on Carbon Nanotubes as Ultra-Long-Life Anodes for Reversible Lithium Storage. Carbon 65-71 BCL2 interacting protein 2 Homo sapiens 34-38 34584950-0 2021 Selective Synthesis of Carbon Nanorings via Asymmetric Intramicellar Phase-Transition-Induced Tip-to-Tip Assembly. Carbon 23-29 TOR signaling pathway regulator Homo sapiens 94-97 34584950-0 2021 Selective Synthesis of Carbon Nanorings via Asymmetric Intramicellar Phase-Transition-Induced Tip-to-Tip Assembly. Carbon 23-29 TOR signaling pathway regulator Homo sapiens 101-104 28323408-5 2017 Monodispersed carbon-coated cubic NiP2 nanoparticles anchored on carbon nanotubes (NiP2@C-CNTs) as a proof-of-concept were designed and synthesized. Carbon 14-20 BCL2 interacting protein 2 Homo sapiens 34-38 34584950-2 2021 Herein, we report a precise synthesis of carbon nanorings with a well-defined morphology and tunable thickness based on asymmetric intramicellar phase-transition-induced tip-to-tip assembly via mixing hydrophobic long-chain octadecanol and block copolymer F127. Carbon 41-47 TOR signaling pathway regulator Homo sapiens 170-173 34584950-2 2021 Herein, we report a precise synthesis of carbon nanorings with a well-defined morphology and tunable thickness based on asymmetric intramicellar phase-transition-induced tip-to-tip assembly via mixing hydrophobic long-chain octadecanol and block copolymer F127. Carbon 41-47 TOR signaling pathway regulator Homo sapiens 177-180 28323408-5 2017 Monodispersed carbon-coated cubic NiP2 nanoparticles anchored on carbon nanotubes (NiP2@C-CNTs) as a proof-of-concept were designed and synthesized. Carbon 14-20 BCL2 interacting protein 2 Homo sapiens 83-87 34280615-0 2021 Pan2-Pan3 complex, together with Ccr4-Not complex, has a role in the cell growth on non-fermentable carbon sources. Carbon 100-106 poly(A)-specific ribonuclease Saccharomyces cerevisiae S288C 0-4 34280615-5 2021 Ccr4, Pan2, and Pan3 were phosphorylated in GlyLac medium, suggesting that the activities of Ccr4, Pan2, and Pan3 may be regulated by phosphorylation in response to change of carbon sources. Carbon 175-181 poly(A)-specific ribonuclease Saccharomyces cerevisiae S288C 6-10 34280615-5 2021 Ccr4, Pan2, and Pan3 were phosphorylated in GlyLac medium, suggesting that the activities of Ccr4, Pan2, and Pan3 may be regulated by phosphorylation in response to change of carbon sources. Carbon 175-181 poly(A)-specific ribonuclease Saccharomyces cerevisiae S288C 99-103 28323408-5 2017 Monodispersed carbon-coated cubic NiP2 nanoparticles anchored on carbon nanotubes (NiP2@C-CNTs) as a proof-of-concept were designed and synthesized. Carbon 65-71 BCL2 interacting protein 2 Homo sapiens 34-38 34280615-7 2021 Our results suggest that the Pan2-Pan3 complex, together with the Ccr4-Not complex, has important roles in the growth on non-fermentable carbon sources. Carbon 137-143 poly(A)-specific ribonuclease Saccharomyces cerevisiae S288C 29-33 28349153-2 2017 In this Article, we report that an Al-doped CoP nanoarray on carbon cloth (Al-CoP/CC) behaves as a durable hydrogen evolution electrocatalyst with superhigh activity in 0.5 M H2SO4. Carbon 61-67 caspase recruitment domain family member 16 Homo sapiens 44-47 34533166-0 2021 Tailoring unique neural-network-type carbon nanofibers inserted in CoP/NC polyhedra for robust hydrogen evolution reaction. Carbon 37-43 caspase recruitment domain family member 16 Homo sapiens 67-70 34533166-2 2021 Herein we designed and tailored a unique three-dimensional cross-linked neural network-like CoP-based composite, that is, carbon nanofibers inserted in CoP/NC polyhedra derived from in situ self-assembled bacterial cellulose (BC) wired ZIF-67 polyhedra via high-temperature carbonization and subsequent phosphorization. Carbon 122-128 caspase recruitment domain family member 16 Homo sapiens 92-95 34533166-2 2021 Herein we designed and tailored a unique three-dimensional cross-linked neural network-like CoP-based composite, that is, carbon nanofibers inserted in CoP/NC polyhedra derived from in situ self-assembled bacterial cellulose (BC) wired ZIF-67 polyhedra via high-temperature carbonization and subsequent phosphorization. Carbon 122-128 caspase recruitment domain family member 16 Homo sapiens 152-155 34533166-3 2021 The obtained integrated catalyst (3-D CNF@CoP/NC) consists of CoP/NC polyhedra with abundant active sites as the "neurons" and carbon nanofibers as the "axons", and displayed remarkable activity with an overpotential of 64.5 mV and 105.6 mV at 10 mA cm-2 in 0.5 M H2SO4 and 1 M KOH respectively and good stability with negligible current change after 80 h of chronoamperometric measurement or 4000 CV cycles. Carbon 127-133 caspase recruitment domain family member 16 Homo sapiens 42-45 28349153-2 2017 In this Article, we report that an Al-doped CoP nanoarray on carbon cloth (Al-CoP/CC) behaves as a durable hydrogen evolution electrocatalyst with superhigh activity in 0.5 M H2SO4. Carbon 61-67 caspase recruitment domain family member 16 Homo sapiens 78-81 28211874-0 2017 dATF4 regulation of mitochondrial folate-mediated one-carbon metabolism is neuroprotective. Carbon 54-60 cryptocephal Drosophila melanogaster 0-5 28211874-3 2017 In Drosophila pink1 and parkin mutants, mitochondrial defects lead to the compensatory upregulation of the mitochondrial one-carbon cycle metabolism genes by an unknown mechanism. Carbon 125-131 PTEN-induced putative kinase 1 Drosophila melanogaster 14-19 28211874-5 2017 We show that ATF4 regulates the expression of one-carbon metabolism genes SHMT2 and NMDMC as a protective response to mitochondrial toxicity. Carbon 50-56 cryptocephal Drosophila melanogaster 13-17 28234466-6 2017 In summary, we present the first evidence that OCTN2 can act as a new molecular target for oral prodrug delivery and, importantly, the linkage carbon chain length is a key factor in modifying the affinity of the substrate for OCTN2. Carbon 143-149 solute carrier family 22 member 2 Homo sapiens 47-52 34388501-1 2021 An integrated computational fluid dynamics (CFD)-kinetic model framework was developed to numerically describe the hydrodynamic and kinetic phenomena in a liquid-solid two phases Fluidized-bed reactor Fenton/granular activated carbon (FBR-Fenton/GAC) system. Carbon 227-233 glutaminase Homo sapiens 246-249 34571785-3 2021 Monophosphoryl lipid A (MPL); a TLR4 agonist, and Poly I:C; a TLR3 agonist, are known as a strong immuno-stimulator which induce Th1 response. Carbon 57-58 toll-like receptor 3 Mus musculus 62-66 34192656-6 2021 The largest discrepancies were observed in the 1700-1000 cm-1 region, likely due to the coupling with the OH and CHalpha in-plane bending vibrations, such as nuaC = C-C = Omicron, nusC = C-C = Omicron and deltaOH. Carbon 165-166 transcription factor like 5 Homo sapiens 113-120 34192656-6 2021 The largest discrepancies were observed in the 1700-1000 cm-1 region, likely due to the coupling with the OH and CHalpha in-plane bending vibrations, such as nuaC = C-C = Omicron, nusC = C-C = Omicron and deltaOH. Carbon 187-188 transcription factor like 5 Homo sapiens 113-120 28234466-6 2017 In summary, we present the first evidence that OCTN2 can act as a new molecular target for oral prodrug delivery and, importantly, the linkage carbon chain length is a key factor in modifying the affinity of the substrate for OCTN2. Carbon 143-149 solute carrier family 22 member 2 Homo sapiens 226-231 28287220-4 2017 For the first time, its sodium intercalation mechanism in an aqueous electrolyte is explored, and moreover, the well-aligned NaV3(PO4)3@porous carbon nanofiber is constructed to fulfil its full potential. Carbon 143-149 neuron navigator 3 Homo sapiens 125-129 34246002-2 2021 This study proposed a novel free RMnS generation method in ultrasound enhanced carbon nanotube (CNTs)/permanganate process (UCP) for organics removal. Carbon 79-85 uncoupling protein 1 Homo sapiens 124-127 6800407-1 1982 Exposure of dark-grown resting (carbon deficient) Euglena to light, ethanol or malate produced a transient increase in the specific activity of fumarase. Carbon 32-38 fumarate hydratase Homo sapiens 144-152 28287220-6 2017 Favored by the well-aligned, highly porous and hierarchical 1D nanoarchitecture, the freestanding aligned NaV3(PO4)3@porous carbon hybrid film achieves fast electron/ion transport capability and good mechanical flexibility, resulting in its superior high-rate properties and excellent cycling durability. Carbon 124-130 neuron navigator 3 Homo sapiens 106-110 28265077-6 2017 These results demonstrate that MTHFD1 and SHMT1, which are key enzymes providing one-carbon units for dTMP biosynthesis in the form of 5,10-methylenetetrahydrofolate, are direct targets of As2O3-induced proteolytic degradation, providing a mechanism for arsenic in the etiology of cancer and developmental anomalies. Carbon 85-91 serine hydroxymethyltransferase 1 Homo sapiens 42-47 6329694-3 1982 Strains containing this plasmid produced a PGK-interferon-alpha fusion protein as 1-2% of cell protein and the expression of interferon activity was regulated by the availability of a fermentable carbon source. Carbon 196-202 interferon alpha Mus musculus 47-63 34559076-1 2021 An excellent magnetic multi-walled carbon nanotubes (MMWCNT) containing carboxyl material modified with ferroferric oxide (Fe3O4) nanoparticles was synthesized as the adsorbent for magnetic solid-phase extraction (MSPE) of five heavy metal ions (Pb2+, Cu2+, Co2+, Cd2+, Cr4+) in water samples followed by on-line inductively coupled plasma mass spectrometry (ICP-MS) detection. Carbon 35-41 CD2 molecule Homo sapiens 264-267 34764826-0 2021 Ultra pH-sensitive detection of total and free prostate-specific antigen using electrochemical aptasensor based on reduced graphene oxide/gold nanoparticles emphasis on TiO2/carbon quantum dots as a redox probe. Carbon 174-180 kallikrein related peptidase 3 Homo sapiens 47-72 34764826-3 2021 The sensing platform relies on PSA recognition by aptamer/Au/GO-nanohybrid-modified glassy carbon electrode. Carbon 91-97 kallikrein related peptidase 3 Homo sapiens 31-34 30108813-3 2017 The chirality of the carbon bearing the C2 substituent, as well as the position of the hydroxyl (tolerated at C5, but not at C3) has profound influence on the inhibitory activity of both DAGLalpha and ABHD6, as established using biochemical assays and competitive activity-based protein profiling on mouse brain extracts. Carbon 21-27 diacylglycerol lipase, alpha Mus musculus 187-196 34477753-4 2021 In this work, endogenous bile pigments bilirubin (BR) and biliverdin (BV) were used for the first time to synthesize stimuli-responsive carbon dots (BR-CDots and BV-CDots respectively). Carbon 136-142 chromosome 12 open reading frame 73 Homo sapiens 50-52 6449507-7 1980 Methylation analysis of product formed either with mucin acceptor or Gal beta 1-3GalNAc-alpha-O-benzyl indicated GlcNAc transfer to either carbon 4 or carbon 6 of the GalNAc residue of the acceptors. Carbon 139-145 mucin Canis lupus familiaris 51-56 7372610-1 1980 We describe the interactions at 25 degrees C of the 3-carbanions (I-) and 3-carbon conjugate acids (I) of 3-nitropropionate, 3-nitro-2-hydroxypropionate, and 3-nitro-2-aminopropionate with fumarase and aspartase. Carbon 76-82 fumarate hydratase Homo sapiens 189-197 34477753-4 2021 In this work, endogenous bile pigments bilirubin (BR) and biliverdin (BV) were used for the first time to synthesize stimuli-responsive carbon dots (BR-CDots and BV-CDots respectively). Carbon 136-142 chromosome 12 open reading frame 73 Homo sapiens 149-151 28244521-3 2017 The obtained materials consisting of TMP nanoparticles (NPs) are encapsulated in N,P-codoped carbon (NPC). Carbon 93-99 NPC intracellular cholesterol transporter 1 Homo sapiens 101-104 34485261-4 2021 The highest average surface-corrected MCCA extraction rate of 655.2 +- 86.4 mmol C m-2 d-1 was obtained, which was higher than any other previous reports, albeit the relatively small surface area removed only 11.6% of the introduced carbon via pertraction. Carbon 233-239 methylcrotonyl-CoA carboxylase subunit 1 Homo sapiens 38-42 222335-0 1979 Reduction of ferricytochrome c, methemoglobin and metmyoglobin by hydroxyl and alcohol radicals. Carbon 4-5 hemoglobin subunit gamma 2 Homo sapiens 32-45 222335-3 1979 The OH radicals which reduce the ferricytochrome c with a yield of (30 +/- 10)% and methemoglobin with a yield of (40 +/- 10)%. Carbon 11-12 hemoglobin subunit gamma 2 Homo sapiens 84-97 112721-1 1979 The time dependence of the level of blood cholinesterase was determined in rats with the reticulo-endothelial system (RES) inhibited with colloidal carbon and in control rats after i.v. Carbon 148-154 butyrylcholinesterase Rattus norvegicus 42-56 28061425-8 2017 Furthermore, clustering analysis of the inflammatory cytokines revealed a similarity of NCF to the carbon nanofibers response and CNC to the chitin, a known immune modulator and innate cell activator. Carbon 99-105 neutrophil cytosolic factor 4 Homo sapiens 88-91 112721-5 1979 However, when the RES is inhibited with colloidal carbon, "reactivation" of cholinesterase is significantly slowed down, to a varying degree, depending on the dose of carbaryl. Carbon 50-56 butyrylcholinesterase Rattus norvegicus 76-90 728109-12 1978 In contrast, the later time intervals (3--17 h) were characterized by the appearance of 14C in C-1 and C-3 and decreasing amounts of 14C in C-2 and C-6. Carbon 90-91 complement C3 Rattus norvegicus 95-106 34319734-5 2021 Comparisons with acetylene complexes of 1,1,2-trifluoroethylene and cis-1,2-difluoroethylene show the effects of halogen substitution at the remote carbon on this bonding motif. Carbon 148-154 suppressor of cytokine signaling 1 Homo sapiens 68-73 28280500-3 2017 In addition, thioredoxin-mediated redox regulation of Calvin cycle enzymes has been shown to determine the efficiency of carbon assimilation. Carbon 121-127 thioredoxin Homo sapiens 13-24 34323067-2 2021 Cytoplasmic citrate flux, mediated by plasma membrane citrate transporter (SLC13A5), mitochondrial citrate carrier (SLC25A1), and ATP-dependent citrate lyase (ACLY), determines the central carbon source for acetyl-CoA required in DNL. Carbon 189-195 solute carrier family 13 member 5 Homo sapiens 75-82 34323067-2 2021 Cytoplasmic citrate flux, mediated by plasma membrane citrate transporter (SLC13A5), mitochondrial citrate carrier (SLC25A1), and ATP-dependent citrate lyase (ACLY), determines the central carbon source for acetyl-CoA required in DNL. Carbon 189-195 solute carrier family 25 member 1 Homo sapiens 116-123 77332-9 1978 Furthermore, whereas the PC I and virion-derived reverse transcriptase copied poly(C). Carbon 83-85 serine (or cysteine) peptidase inhibitor, clade A, member 5 Mus musculus 25-29 27340756-3 2017 The effect of some factors on beta-glucosidase production was studied including: Initial pH, medium composition, concentration of carbon and nitrogen sources, and particle size of raw substrates. Carbon 130-136 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1a, chloroplastic Triticum aestivum 30-46 614009-4 1977 In the other type the range of carbon sources which induce the catechol 2,3-dioxygenase was increased. Carbon 31-37 catechol 2,3-dioxygenase Pseudomonas putida 63-87 34148421-7 2021 (doi:10.1098/rsta.2020.0296)) shows in this volume that attempts to use ASTM D5868 to standardize welded composite (carbon fibre reinforced polymer, CFRP) lap joints reveal major problems. Carbon 116-122 LAP Homo sapiens 155-158 27916559-8 2017 The interference of rhinacanthin-C on the ABC drug transporters (P-gp, MRP1 and MRP2) was evaluated by substrate accumulation assay, using fluorescence spectroscopy technique. Carbon 33-34 phosphoglycolate phosphatase Homo sapiens 65-69 34286811-0 2021 Multiscale pore contained carbon nanofiber-based field-effect transistor biosensors for nesfatin-1 detection. Carbon 26-32 nucleobindin 2 Homo sapiens 88-98 34286811-3 2021 In this study, we develop a multiscale pore contained carbon nanofiber-based field-effect transistor (FET) biosensor to detect NES1. Carbon 54-60 nucleobindin 2 Homo sapiens 127-131 831221-7 1977 Speculation The increase of mitochondrial PC activity and PC protein in the neonatal liver will lead to a greater availability of glucogenic carbon in the cytosol and will make a significant contribution to the overall enhancement of neonatal gluconeogenesis. Carbon 141-147 pyruvate carboxylase Rattus norvegicus 42-44 831221-7 1977 Speculation The increase of mitochondrial PC activity and PC protein in the neonatal liver will lead to a greater availability of glucogenic carbon in the cytosol and will make a significant contribution to the overall enhancement of neonatal gluconeogenesis. Carbon 141-147 pyruvate carboxylase Rattus norvegicus 58-60 27756043-6 2017 The median values of the carbon-based MC contents in the sediments, primary consumers, and secondary consumers in the bay were 87, 160, and 250 ngMC gC-1, respectively. Carbon 25-31 solute carrier family 25 member 22 Homo sapiens 149-153 1007910-2 1976 The binding of CS2 carbon was measured in the same fractions of two adult control rats 4.5 h after a similar administration of 1.3 mumol of the compound for reference. Carbon 19-25 calsyntenin 2 Rattus norvegicus 15-18 1007910-8 1976 The binding of CS2 carbon was negligible 4.5 h after the injection in the axonal fraction. Carbon 19-25 calsyntenin 2 Rattus norvegicus 15-18 34340715-0 2021 miR221 regulates cell migration by targeting annexin a1 expression in human mesothelial MeT-5A cells neoplastic-like transformed by multi-walled carbon nanotube. Carbon 145-151 microRNA 221 Homo sapiens 0-6 27771568-8 2017 This carbon surface coverage can control the release of Cd2+ ions in CdO-2 compared to non-covered CdO-1 nanoparticles and hence mitigate the toxicity in the case of CdO-2. Carbon 5-11 CD2 molecule Homo sapiens 56-59 34157283-2 2021 The 9-carbon backbone of sialic acids can undergo extensive enzymatic modification in nature and O-acetylation at the C-4/7/8/9 position in particular is widely observed. Carbon 6-12 complement C4A (Rodgers blood group) Homo sapiens 118-127 34264072-4 2021 This approach has been validated in our study of CoII/CoI redox transformation for Co tetraphenylporphyrin (CoTPP) immobilized on carbon cloth and multiwalled carbon nanotubes (CNTs) - one of the most active heterogeneous molecular catalysts in carbon dioxide (CO2) electroreduction. Carbon 130-136 mitochondrially encoded cytochrome c oxidase I Homo sapiens 54-57 34264072-4 2021 This approach has been validated in our study of CoII/CoI redox transformation for Co tetraphenylporphyrin (CoTPP) immobilized on carbon cloth and multiwalled carbon nanotubes (CNTs) - one of the most active heterogeneous molecular catalysts in carbon dioxide (CO2) electroreduction. Carbon 159-165 mitochondrially encoded cytochrome c oxidase I Homo sapiens 54-57 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 61-67 insulin receptor substrate 1 Homo sapiens 205-210 941178-7 1976 GLC determinations show that hydroxylation has occurred at C-4-C-6-C-2. Carbon 2-3 LOW QUALITY PROTEIN: complement component C6 Oryctolagus cuniculus 63-66 56174-9 1975 The two naturally occurring proteins (alpha-foetoprotein and 17beta-hydroxy steroid dehydrogenase) recognize the edge of the steroid defined by C-4, C-6, C-8 and C-15. Carbon 144-145 nuclear distribution C, dynein complex regulator Rattus norvegicus 162-166 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 69-71 insulin receptor substrate 1 Homo sapiens 205-210 27771568-8 2017 This carbon surface coverage can control the release of Cd2+ ions in CdO-2 compared to non-covered CdO-1 nanoparticles and hence mitigate the toxicity in the case of CdO-2. Carbon 5-11 cysteine dioxygenase type 1 Homo sapiens 99-104 28073929-3 2017 We looked at carbon loss, known to occur in the heterologous flavonoid pathway in yeast, and identified an endogenous enzyme, the enoyl reductase Tsc13, which turned out to be responsible for the accumulation of phloretic acid via reduction of p-coumaroyl-CoA. Carbon 13-19 trans-2-enoyl-CoA reductase (NADPH) TSC13 Saccharomyces cerevisiae S288C 146-151 34298863-1 2021 Arabidopsis thaliana purple acid phosphatase 2 (AtPAP2), which is anchored to the outer membranes of chloroplasts and mitochondria, affects carbon metabolism by modulating the import of some preproteins into chloroplasts and mitochondria. Carbon 140-146 Purple acid phosphatases superfamily protein Arabidopsis thaliana 21-46 34298863-1 2021 Arabidopsis thaliana purple acid phosphatase 2 (AtPAP2), which is anchored to the outer membranes of chloroplasts and mitochondria, affects carbon metabolism by modulating the import of some preproteins into chloroplasts and mitochondria. Carbon 140-146 Purple acid phosphatases superfamily protein Arabidopsis thaliana 48-54 34138542-4 2021 We show for the first time that atomically dispersed Pt-N3C1 sites planted on nitrogen-doped carbon nanotubes (Pt1/N-CNTs), constructed via a stepwise polymerization-carbonization-electrostatic adsorption strategy, are highly active and selective toward Calpha-Cbeta bond cleavage in beta-O-4 model compounds under ambient conditions. Carbon 93-99 zinc finger protein 77 Homo sapiens 111-114 1191633-1 1975 13C relaxation parameters, T1, line width, and NOE, have been determined for backbone carbons of ligamentum nuchae elastin swollen by 0.15 M NaCl, 0.15 M NaCl-formamide, 0.15 M NaCl-ethanol, dimethyl sulfoxide, and formamide. Carbon 86-93 elastin Homo sapiens 115-122 1220690-4 1975 The observations suggest a route for the incorporation of glutamate carbon into glycine that involves C-5 but not C-2. Carbon 68-74 complement C5 Cavia porcellus 102-105 27818152-3 2017 To address this dilemma, we design a synergetic carbon utilization mechanism (SynCar), in which glucose catabolism is inactivated and a second carbon source (e.g. glycerol) is employed to maintain cell growth and rationally strengthen PEP driving force for glucose uptake and non-catabolic utilization. Carbon 48-54 progestagen associated endometrial protein Homo sapiens 235-238 240105-1 1975 The effect of pH, carbon sources, and some organic substances on the biosynthesis of beta-galactosidase was studied in Alternaria tenuis on a defined medium that had been optimized by the method of mathematical planning of experiments. Carbon 18-24 CC77DRAFT_1020447 Alternaria alternata 85-103 27825117-2 2016 C-containing genotypes of miR-149 rs2292832 were associated with better overall survival (OS). Carbon 0-1 microRNA 149 Homo sapiens 26-33 4525318-1 1974 Carbon-13 spin-lattice relaxation time measurements of amino acids. Carbon 0-6 spindlin 1 Homo sapiens 10-14 4525318-4 1974 For the carboxyl carbon, spin rotation is proposed as the predominant relaxation mechanism, whereas the other carbons are relaxed mainly by the dipole-dipole mechanism, and their relaxation times are relatively independent of changes in concentration and pD. Carbon 17-23 spindlin 1 Homo sapiens 25-29 34179632-0 2021 PEG/Sodium Tripolyphosphate-Modified Chitosan/Activated Carbon Membrane for Rhodamine B Removal. Carbon 56-62 progestagen associated endometrial protein Homo sapiens 0-3 34179632-6 2021 The adsorption efficiency and reusability of the PEG/TPP-modified CS/AC membrane to remove RhB were investigated based on dynamic and static adsorption models. Carbon 69-71 progestagen associated endometrial protein Homo sapiens 49-52 34179632-7 2021 The results reveal that the adsorption performance of CS/AC membranes was significantly improved after the PEG/TPP modification based on the abundance macroporous structure. Carbon 57-59 progestagen associated endometrial protein Homo sapiens 107-110 27934851-0 2016 Corrigendum: Using rare earth elements to constrain particulate organic carbon flux in the East China Sea. Carbon 72-78 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 102-105 34072043-0 2021 Pristine and Poly(Dimethylsiloxane) Modified Multi-Walled Carbon Nanotubes as Supports for Lipase Immobilization. Carbon 58-64 PAN0_003d1715 Moesziomyces antarcticus 91-97 4268097-4 1973 The substrate-level pathway, which was active with glucose but not with D-lactate as the carbon source, was sensitive to arsenate but not to cyanide, and required a functional ATPase. Carbon 89-95 ATPase Escherichia coli 176-182 4515601-2 1973 Spin-lattice relaxation (T(1)) of the [(13)C]carbons of the sugar was measured in the absence and presence of the two transition metal derivatives of the protein. Carbon 45-52 spindlin 1 Homo sapiens 0-4 27778379-7 2016 Furthermore, the as-synthesized PCs were processed with KOH to obtain activated porous carbon materials (APCs) with higher specific surface area and porosity, which greatly promoted the energy-storage capacity. Carbon 87-93 amyloid P component, serum Homo sapiens 105-109 34168900-0 2021 ASPHER Statement: Towards a Carbon-Neutral Association of Schools of Public Health in the European Region. Carbon 28-34 aspartate beta-hydroxylase Homo sapiens 0-6 26887579-1 2016 A biosensor for measuring the antidiabetic potential of medicinal plants was developed by covalent immobilization of alpha-glucosidase (AG) enzyme onto amine-functionalized multi-walled carbon nanotubes (MWCNTs-NH2). Carbon 186-192 sucrase-isomaltase Homo sapiens 117-134 34163665-4 2021 In addition, the electron-rich sulfur atoms also raise the energies of both the HOMO and LUMO in MC4-S, but the overall optical and electronic energy gaps are close to that of the CPTP-M. MC4-S displays global anti-aromaticity according to the NMR measurements and theoretical calculations (NICS, ACID and 2D ICSS), with a 36pi ring current circuit along the all-carbon periphery excluding the two sulphur atoms. Carbon 363-369 ceramide-1-phosphate transfer protein Homo sapiens 180-184 4683519-1 1973 In rabbits, when renal glomerular capillary thrombosis was induced by an infusion of thrombin, injected colloidal carbon particles localized within glomeruli. Carbon 114-120 prothrombin Oryctolagus cuniculus 85-93 4683519-2 1973 When administered after the thrombin had been infused, carbon was attached to the surface of fibrin deposits. Carbon 55-61 prothrombin Oryctolagus cuniculus 28-36 4683519-4 1973 If administered simultaneously with thrombin, the carbon was incorporated into the developing mass of fibrin. Carbon 50-56 prothrombin Oryctolagus cuniculus 36-44 35430407-3 2022 We have designed novel immunosensors targeting conserved protein sequences of the N protein of SARS-CoV-2 based on lab-produced and purified anti-SARS-CoV-2 nucleocapsid antibodies that are densely grafted onto various surfaces (diamond/gold/glassy carbon). Carbon 249-255 nucleocapsid phosphoprotein Severe acute respiratory syndrome coronavirus 2 82-83 26887579-1 2016 A biosensor for measuring the antidiabetic potential of medicinal plants was developed by covalent immobilization of alpha-glucosidase (AG) enzyme onto amine-functionalized multi-walled carbon nanotubes (MWCNTs-NH2). Carbon 186-192 sucrase-isomaltase Homo sapiens 136-138 26897549-4 2016 We suggest that overexpression of PEPC played an anaplerotic role to increase the supply of 4-carbon carboxylic acids, which provided carbon skeletons for increased amino acid and protein synthesis. Carbon 94-100 MLO-like protein 4 Zea mays 34-38 35430311-8 2022 Higher proportions of charophytes and greater dissolved inorganic carbon in more oligotrophic lakes corresponded to less periphyton Se uptake. Carbon 66-72 squalene epoxidase Homo sapiens 132-134 4634828-4 1972 The carbon skeletons of formate and succinate were shown to arise from the C-2 and the C-3-C-6 atoms of the heterocyclic ring respectively by using N-methyl[2,3-(14)C(2)]isonicotinate. Carbon 4-10 complement C3 Homo sapiens 87-90 4322517-2 1971 The action of N-acetylneuraminic acid aldolase on 8-carbon and 7-carbon analogues. Carbon 52-58 N-acetylneuraminate pyruvate lyase Homo sapiens 14-46 4322517-2 1971 The action of N-acetylneuraminic acid aldolase on 8-carbon and 7-carbon analogues. Carbon 65-71 N-acetylneuraminate pyruvate lyase Homo sapiens 14-46 27767019-3 2016 In this paper, we demonstrate that cobalt phosphide nanowall arrays supported on carbon cloth (CoP NAs/CC) efficiently catalyze the hydrolytic dehydrogenation of NaBH4 with an activation energy of 42.1 kJ mol-1 in alkaline media. Carbon 81-87 caspase recruitment domain family member 16 Homo sapiens 95-98 5263759-2 1970 The study has yielded the magnitude and sign of spin densities at the carbon atoms in the pi system of the 9-cis, 13-cis, and all trans isomers. Carbon 70-76 spindlin 1 Homo sapiens 48-52 27799657-3 2016 By developing genetically engineered mouse models and primary pancreatic epithelial cells, and employing transcriptional, proteomics, and metabolic analyses, we find that oncogenic cooperation between LKB1 loss and KRAS activation is fuelled by pronounced mTOR-dependent induction of the serine-glycine-one-carbon pathway coupled to S-adenosylmethionine generation. Carbon 307-313 Kirsten rat sarcoma viral oncogene homolog Mus musculus 215-219 20048818-3 1966 In addition, a revised treatment of the rate of energy transfer from hot carbon ions to the very cold electrons (upsilon_ < upsilon(+)) reduces the conventional ion cooling rate by a factor of about 6. Carbon 73-79 alcohol dehydrogenase iron containing 1 Homo sapiens 69-72 35279638-3 2022 Here we establish an electrochemical biosensor which was developed based on molybdenum disulfide (MoS2) and multi-wall carbon nanotubes (MWCNTs) used to modify the electrode and PD-L1 antibody-quantum dot (QD) conjugate as a dual optical and electrochemical label. Carbon 119-125 CD274 molecule Homo sapiens 178-183 27799657-3 2016 By developing genetically engineered mouse models and primary pancreatic epithelial cells, and employing transcriptional, proteomics, and metabolic analyses, we find that oncogenic cooperation between LKB1 loss and KRAS activation is fuelled by pronounced mTOR-dependent induction of the serine-glycine-one-carbon pathway coupled to S-adenosylmethionine generation. Carbon 307-313 mechanistic target of rapamycin kinase Mus musculus 256-260 27808289-0 2016 Importance of the structural integrity of a carbon conjugated mediator for photocatalytic hydrogen generation from water over a CdS-carbon nanotube-MoS2 composite. Carbon 132-138 CDP-diacylglycerol synthase 1 Homo sapiens 128-131 35594381-0 2022 Metformin adsorption onto activated carbon prepared by acid activation and carbonization of orange peel. Carbon 36-42 SAFB like transcription modulator Homo sapiens 0-9 35594381-13 2022 NOVELTY STATEMENT Orange peel activated carbon (OPAC) adsorbent gave a higher qo value for metformin removal from aqueous solution than other adsorbents previously reported in the literature.The highest percentage of removal of metformin drug-using OPAC was 97.23%. Carbon 40-46 SAFB like transcription modulator Homo sapiens 91-100 35594381-13 2022 NOVELTY STATEMENT Orange peel activated carbon (OPAC) adsorbent gave a higher qo value for metformin removal from aqueous solution than other adsorbents previously reported in the literature.The highest percentage of removal of metformin drug-using OPAC was 97.23%. Carbon 40-46 SAFB like transcription modulator Homo sapiens 228-237 13725782-2 1960 Distribution of the alpha-carbon of dL-methionine-2-C14 in tissues, tissue fractions, expired carbon dioxide, blood and excreta. Carbon 26-32 anti-Mullerian hormone receptor type 2 Rattus norvegicus 52-55 27524043-1 2016 This paper presents the fabrication of a highly sensitive and selective glucose sensor based on cuprous oxide/graphene nanocomposites-modified glassy carbon electrode (Cu2O/graphene/GCE). Carbon 150-156 guanylate cyclase 2E, pseudogene Homo sapiens 182-185 35506547-1 2022 Herein, a so-called carbon nanotube (CNT) electrode was printed in on a paper substrate using the handwriting technique and carbon nanotube ink in a marker pen to print the working electrode, graphite pencil to print the counter electrode and graphite/silver nanoparticle (AgNP) ink in a rollerball pen to print the quasi-reference electrode. Carbon 20-26 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 156-159 35506547-1 2022 Herein, a so-called carbon nanotube (CNT) electrode was printed in on a paper substrate using the handwriting technique and carbon nanotube ink in a marker pen to print the working electrode, graphite pencil to print the counter electrode and graphite/silver nanoparticle (AgNP) ink in a rollerball pen to print the quasi-reference electrode. Carbon 20-26 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 299-302 33870613-3 2021 Deletion of Dsk2 resulted in mild growth defect on scant media with various carbon/nitrogen sources and dramatic attenuation in conidiation capability at optimal condition. Carbon 76-82 ubiquitin domain-containing protein DSK2 Saccharomyces cerevisiae S288C 12-16 27768100-4 2016 The former can proceed more than three orders of magnitude faster than the latter, and involves a rate-limiting attack by a hydroxide at a MIDA carbonyl carbon. Carbon 144-150 NADH:ubiquinone oxidoreductase complex assembly factor 7 Homo sapiens 139-143 34013717-0 2021 Fe/Fe3C Embedded in N-Doped Worm-like Porous Carbon for High-Rate Catalysis in Rechargeable Zinc-Air Batteries. Carbon 45-51 general transcription factor IIE subunit 1 Homo sapiens 0-2 35507679-3 2022 In this work, we report the simple synthesis of TMCs/N-doping carbon aerogels (TMCs/NCAs, including Fe3C/NCA, Mo3C2/NCA, and Fe3C-Mo2C/NCA) for the oxygen reduction reaction (ORR) using protonated chitosan/metal complex anion-chelated aerogels. Carbon 62-68 CEA cell adhesion molecule 6 Homo sapiens 135-138 35588657-4 2022 Mass spectrometry results showed that C-316-1 bound to heat shock protein 90 (Hsp90), which was further confirmed by molecular docking and surface plasmon resonance. Carbon 38-39 heat shock protein 90 alpha family class A member 1 Homo sapiens 55-76 35588657-4 2022 Mass spectrometry results showed that C-316-1 bound to heat shock protein 90 (Hsp90), which was further confirmed by molecular docking and surface plasmon resonance. Carbon 38-39 heat shock protein 90 alpha family class A member 1 Homo sapiens 78-83 35588657-9 2022 Thereby, C-316-1 inhibited the Hsp90-Cdc37 complex formation and led to a significant decrease in RIPK1, which in turn reduced necroptosis. Carbon 9-10 heat shock protein 90 alpha family class A member 1 Homo sapiens 31-36 35588657-9 2022 Thereby, C-316-1 inhibited the Hsp90-Cdc37 complex formation and led to a significant decrease in RIPK1, which in turn reduced necroptosis. Carbon 9-10 receptor interacting serine/threonine kinase 1 Homo sapiens 98-103 35588657-10 2022 Moreover, C-316-1 treatment did not protect against kidney injury in vivo and in vitro when Hsp90 was knocked down and R46, E47, and S50 in Cdc37 binding site of Hsp90 might form an important active pocket with C-316-1. Carbon 211-212 heat shock protein 90 alpha family class A member 1 Homo sapiens 162-167 33934328-3 2021 By analyzing the accumulation of 26 intracellular metabolites and the expression of 90 genes related to central carbon metabolism and stress response, we confirmed that the process oscillation was attributed to intracellular metabolic oscillation with phase difference, and the expression of HXK1, HXT1,2,4 and PFK1 was significantly different from other genes in the Embden-Meyerhof-Parnas pathway, indicating that glucose transport and phosphorylation could be key nodes for regulating the intracellular metabolism under oscillatory conditions. Carbon 112-118 hexose transporter HXT1 Saccharomyces cerevisiae S288C 298-302 35183049-5 2022 Multi-walled carbon nanotubes (MWCNTs) inhibited the translocation of aryl hydrocarbon receptor (AhR) from cytosol to the nucleus, leading to the downregulation of cytochrome P450 family 1 subfamily A member 1 (CYP1A1) and inhibition of detoxification function. Carbon 13-19 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 164-209 35183049-5 2022 Multi-walled carbon nanotubes (MWCNTs) inhibited the translocation of aryl hydrocarbon receptor (AhR) from cytosol to the nucleus, leading to the downregulation of cytochrome P450 family 1 subfamily A member 1 (CYP1A1) and inhibition of detoxification function. Carbon 13-19 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 211-217 27791081-5 2016 In this study, the introduction of an intact CAS gene into H82 cells restored photosynthetic affinity for inorganic carbon, and RNA-seq analyses revealed that CAS could function in maintaining the expression levels of nuclear-encoded CO2-limiting-inducible genes, including the HCO3- transporters high-light activated 3 (HLA3) and low-CO2-inducible gene A (LCIA). Carbon 116-122 BCAR1 scaffold protein, Cas family member Homo sapiens 45-48 34010151-1 2021 BACKGROUND: Catabolism of serine via serine hydroxymethyltransferase2 (SHMT2) through the mitochondrial one-carbon unit pathway is important in tumorigenesis. Carbon 108-114 serine hydroxymethyltransferase 2 Homo sapiens 71-76 27791081-5 2016 In this study, the introduction of an intact CAS gene into H82 cells restored photosynthetic affinity for inorganic carbon, and RNA-seq analyses revealed that CAS could function in maintaining the expression levels of nuclear-encoded CO2-limiting-inducible genes, including the HCO3- transporters high-light activated 3 (HLA3) and low-CO2-inducible gene A (LCIA). Carbon 116-122 BCAR1 scaffold protein, Cas family member Homo sapiens 159-162 33529932-11 2021 The calculations also showed that changes in torsion angles induce a change in reaction coordinates, namely Co-C and C-S bond distances, for the methylation and demethylation reactions catalyzed both by MetH and MtmBC. Carbon 108-109 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 203-207 27786263-0 2016 Irminger Sea deep convection injects oxygen and anthropogenic carbon to the ocean interior. Carbon 62-68 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 9-12 35550508-3 2022 Integrative transcriptomic, metabolomic and functional data reveal that hyperactivation of the serine-glycine-one-carbon network is a metabolic hallmark inherent to CDK12-induced tumorigenesis. Carbon 114-120 cyclin-dependent kinase 12 Mus musculus 165-170 27786263-5 2016 Our observations provide unequivocal evidence that ocean ventilation and anthropogenic carbon uptake take place in the Irminger Sea and that their efficiency can be directly linked to atmospheric forcing. Carbon 87-93 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 128-131 35522478-5 2022 Owing to the presence of highly exposed Fe-N-C sites and well-tuned pore structures, isolated Fe atoms on porous carbon nanofiber framework (Fe-SA/NCF) exhibits decent oxygen reduction activity and stability in alkaline conditions via a near four-electron path, demonstrating superior performance as air cathode for zinc-air batteries (ZABs) to commercial Pt/C catalyst. Carbon 113-119 neutrophil cytosolic factor 4 Homo sapiens 147-150 33946296-0 2021 H2S-Sensing Studies Using Interdigitated Electrode with Spin-Coated Carbon Aerogel-Polyaniline Composites. Carbon 68-74 spindlin 1 Homo sapiens 56-60 27629250-2 2016 Furthermore, the coupling reaction between the aryllithium compounds and aryl ammonium salts proceeded under mild conditions with C-N bond cleavage in the presence of a [Pd(PPh3 )2 Cl2 ] catalyst. Carbon 130-131 protein phosphatase 4 catalytic subunit Homo sapiens 173-177 33899078-7 2021 Poly(I:C) and HSV60 predominantly induced the expression of type 1 interferons (IFNA and IFNB) and antiviral proteins: Mx GTPase 1, 2",5"-oligoadenylate synthetase 1, and IFN-stimulated gene 15. Carbon 7-9 interferon alpha Mus musculus 80-84 33899078-7 2021 Poly(I:C) and HSV60 predominantly induced the expression of type 1 interferons (IFNA and IFNB) and antiviral proteins: Mx GTPase 1, 2",5"-oligoadenylate synthetase 1, and IFN-stimulated gene 15. Carbon 7-9 interferon beta 1, fibroblast Mus musculus 89-93 35601317-5 2022 In this study, the HHS process was used to separate the carbon/ash from the fine gasification slag produced by a Shenning gasifier, Texaco gasifier, and GSP gasifier of Ningxia Coal Industry Co., Ltd. Carbon 56-62 GSM1 Homo sapiens 153-156 35601317-12 2022 Compared with the other two gasifier products, the GSP gasifier concentrate has a larger specific surface area and less ash material, more amorphous carbon structures (less graphitic), and more active sites, resulting in a stronger combustion activity. Carbon 149-155 GSM1 Homo sapiens 51-54 27630061-1 2016 Attempts to prepare previously unknown simple and very Lewis acidic [RZn]+ [Al(ORF )4 ]- salts from ZnR2 , AlR3 , and HO-RF delivered the ion-like RZn(Al(ORF )4 ) (R=Me, Et; RF =C(CF3 )3 ) with a coordinated counterion, but never the ionic compound. Carbon 178-179 cortactin binding protein 2 Homo sapiens 147-160 33406509-2 2021 Herein, we incorporated Sn-based metal-organic framework (Sn-MOF) templates into crosslinked one-dimensional carbon nanofibers (CNFs) through electrospinning strategy and obtained a hierarchical porous film (Sn@C@CNF) after a carbothermal reduction reaction. Carbon 109-115 NPHS1 adhesion molecule, nephrin Homo sapiens 128-131 27232723-4 2016 Bi1-xBa xFeO3 of x=0.2mol% exhibited the greatest photocatalytic degradation effect after 60min of visible light irradiation, and reached 97% benzene removal efficiency, leading to production of a high concentration of carbon dioxide (CO2), with 93% and 82% reductions in chemical oxygen demand (COD) and total organic carbon (TOC), respectively. Carbon 219-225 transmembrane BAX inhibitor motif containing 6 Homo sapiens 0-3 33406509-7 2021 And the carbon wrappings derived from PAN nanofibers and MOF skeleton could jointly accommodate to the violent volume variation during cycling, enabling Sn@C@CNF with excellent cycle stability. Carbon 8-14 NPHS1 adhesion molecule, nephrin Homo sapiens 158-161 33267953-2 2021 Herein, a facile adsorption-pyrolyzation strategy is proposed for preparing ultrafine Ni nanoparticles anchored on carbon nanofiber (Ni/CNF), which derives from pyrolyzation of bacterial cellulose (BC) (with pre-adsorbed of Ni2+) via a two-step heat-treatment procedure (firstly 360 C, and then 750 C) (Ni/CNF-750) and used as an excellent oxygen electrocatalyst for flexible all solid-state Zn-air cell. Carbon 115-121 NPHS1 adhesion molecule, nephrin Homo sapiens 136-139 35294315-8 2022 Implications Adsorptive characteristics by activated carbon materials were examined for benzene and chlorobenzene in gas within the temperature range of 150 to 190 C. The adsorption amount of benzene at high temperature and low concentration range below 20 ppm was in the range of 103 to 104 mg/kg-adsorbent. Carbon 54-60 gastrin Homo sapiens 118-121 35561608-0 2022 Promoting the reduction of CO2 to formate and formaldehyde via gas-liquid interface dielectric barrier discharge using a Zn0.5Cd0.5S/CoP/multiwalled carbon nanotubes catalyst. Carbon 149-155 caspase recruitment domain family member 16 Homo sapiens 133-136 27626106-7 2016 Propagation of the CO2+ interference to other ions during standard AMS and ACSM data analysis affects the calculated OA mass, mass spectra, molecular oxygen-to-carbon ratio (O/C), and f44. Carbon 160-166 complement C2 Homo sapiens 19-22 35417179-2 2022 Here, we use tip-enhanced Raman scattering (TERS) to further enhance the Raman response of a single carbyne chain confined inside a double-walled carbon nanotube. Carbon 146-152 TOR signaling pathway regulator Homo sapiens 13-16 33853774-6 2021 Metabolic flux and transcriptome analysis revealed that Kog1 controls SNF1-dependent carbon flux apportioning between glutamate/amino acid biosynthesis and gluconeogenesis. Carbon 85-91 ubiquitin-binding TORC1 subunit KOG1 Saccharomyces cerevisiae S288C 56-60 33853774-9 2021 Therefore, Kog1 centrally regulates metabolic homeostasis and carbon utilization during nutrient limitation by managing SNF1 activity. Carbon 62-68 ubiquitin-binding TORC1 subunit KOG1 Saccharomyces cerevisiae S288C 11-15 33360887-5 2021 Furthermore, the FeCoNiSx/NF acted as the anode towards overall water electrolysis with acceptable results, where commercial Pt/C dropped on the NF worked as the cathode. Carbon 19-20 neurofascin Homo sapiens 26-28 33360887-5 2021 Furthermore, the FeCoNiSx/NF acted as the anode towards overall water electrolysis with acceptable results, where commercial Pt/C dropped on the NF worked as the cathode. Carbon 19-20 neurofascin Homo sapiens 145-147 35591379-6 2022 Furthermore, because of good balance between CH4 dissociation and CO2 dissociation, NiP-2/Al2O3 catalyst exhibits best resistance of carbon deposition, few carbon depositions were formed after 50 h of dry methane reforming. Carbon 133-139 BCL2 interacting protein 2 Homo sapiens 84-89 27178553-1 2016 Sensitive impedimetric detection of miR-222, a miRNA sequence found in many lung tumors, was investigated by using gold-nanostructured disposable carbon electrodes and enzyme-decorated liposomes. Carbon 146-152 microRNA 222 Homo sapiens 36-43 35629773-5 2022 The FeOOH-GA was used as a support material on the glass carbon electrode (GCE) for glucose oxidase (GOD). Carbon 57-63 guanylate cyclase 2E, pseudogene Homo sapiens 75-78 33592776-2 2021 This work reports a magnetic microbeads (MBs)-based sandwich immunoassay for the amperometric determination of MMP-9 at screen-printed carbon electrodes (SPCEs). Carbon 135-141 matrix metallopeptidase 9 Homo sapiens 111-116 33576609-3 2021 ATF1 coding AATase was coexpressed in expression cassettes of ACS1/ACS2 and ALD6 to promote the carbon flux toward ethyl acetate from acetyl-CoA. Carbon 96-102 alcohol O-acetyltransferase Saccharomyces cerevisiae S288C 0-4 26995596-5 2016 METHODS: The program was written in C++ using the open-source libraries ITK, VTK, GDCM and Qt. Carbon 36-39 IL2 inducible T cell kinase Homo sapiens 72-75 33153715-6 2021 Given the excellent electrical conductivity of Ti3C2 MXene, the Ti3C2-PLL-GOx nanosheets are further deposited on glassy carbon electrode to construct a high-performance biosensor with a glucose detection limit of 2.6 muM. Carbon 121-127 hydroxyacid oxidase 1 Homo sapiens 74-77 35454915-8 2022 In proton beam irradiation, normal cell lines had less variation in RBE values (within 10%), whereas in carbon-ion irradiation, RBE values differed by up to 48% between hTERT-HME1 and NuLi-1. Carbon 104-110 telomerase reverse transcriptase Homo sapiens 169-179 27593893-3 2016 The outcomes of the feasible C H activation of olefin carbon (C-2) by iridium catalyst are compared with the reduction of the carbonyl group (C-3) by freshly prepared borodeuterides. Carbon 54-60 complement C2 Homo sapiens 62-65 35380441-0 2022 Spin-Forbidden Carbon-Carbon Bond Formation in Vibrationally Excited alpha-CO. Carbon 15-21 kallikrein related peptidase 15 Homo sapiens 69-77 35380441-0 2022 Spin-Forbidden Carbon-Carbon Bond Formation in Vibrationally Excited alpha-CO. Carbon 22-28 kallikrein related peptidase 15 Homo sapiens 69-77 33691293-1 2021 In the present study, a novel silver nanoparticles-decorated three-dimensional graphene-like porous carbon (Ag/3D GPC) nanocomposite has been synthesized via the method of carbonization and reduction of silver ions at the same time. Carbon 100-106 glycophorin C (Gerbich blood group) Homo sapiens 114-117 27519409-9 2016 Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris. Carbon 177-183 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 73-77 27519409-9 2016 Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris. Carbon 177-183 glutamate--ammonia ligase Saccharomyces cerevisiae S288C 83-87 27131995-0 2016 Highly fluorescent carbon dots as selective and sensitive "on-off-on" probes for iron(III) ion and apoferritin detection and imaging in living cells. Carbon 19-25 ferritin heavy chain 1 Homo sapiens 99-110 33615793-2 2021 With the AAA approach introduced herein, challenging 3,3"-bisindolines bearing an all-carbon quaternary stereocenter (C3a) have been constructed in good yields with good to excellent enantioselectivties. Carbon 86-92 complement C3 Homo sapiens 118-121 33586959-0 2021 Nucleolin-Targeted Ratiometric Fluorescent Carbon Dots with a Remarkably Large Emission Wavelength Shift for Precise Imaging of Cathepsin B in Living Cancer Cells. Carbon 43-49 cathepsin B Homo sapiens 128-139 35347335-5 2022 By computing the energetics of C-H bond activation and mapping the potential energy surface, it was found that the initial hydrogen abstraction is the rate-determining step with both TMC rings and all the studied metal-superoxo species. Carbon 31-32 STT3 oligosaccharyltransferase complex catalytic subunit A Homo sapiens 183-186 35149585-9 2022 Together these data identify a short isoform of GAPDHS that limits melanoma metastasis and regulates central carbon metabolism. Carbon 109-115 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Homo sapiens 48-54 27626943-5 2016 Here we show that the carbon footprint of hydropower is far higher than previously assumed, with a global average of 173 kg CO2 and 2.95 kg CH4 emitted per MWh of electricity produced. Carbon 22-28 complement C2 Homo sapiens 124-133 35378389-0 2022 SlMYC2 mediates jasmonate-induced tomato leaf senescence by promoting chlorophyll degradation and repressing carbon fixation. Carbon 109-115 transcription factor MYC2 Solanum lycopersicum 0-6 35378389-4 2022 Here, we report that tomato MYC2, a key factor in the JA signal transduction, functions in JA-induced tomato leaf senescence by promoting chlorophyll degradation and inhibiting photosynthetic carbon fixation. Carbon 192-198 transcription factor MYC2 Solanum lycopersicum 28-32 33860190-0 2021 A Review of Small-Molecule Inhibitors of One-Carbon Enzymes: SHMT2 and MTHFD2 in the Spotlight. Carbon 45-51 serine hydroxymethyltransferase 2 Homo sapiens 61-66 33860190-0 2021 A Review of Small-Molecule Inhibitors of One-Carbon Enzymes: SHMT2 and MTHFD2 in the Spotlight. Carbon 45-51 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 71-77 27586456-1 2016 Sedoheptulose-1, 7-bisphosphatase (SBPase) is an important enzyme involved in photosynthetic carbon fixation in the Calvin cycle. Carbon 93-99 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 0-33 33639933-2 2021 Methylenetetrahydrofolate reductase (MTHFR) gene is one of the genes in One Carbon Metabolic (OCM) pathway that affects both blood pressure and epigenetic phenomenon. Carbon 76-82 methylenetetrahydrofolate reductase Homo sapiens 0-35 35407188-1 2022 Cu(im)2-derived Cu@N-C composites were used for the first time as efficient heterogeneous catalysts for one-pot 1,3-dipolar cycloaddition of terminal alkynes, aryl halides, and sodium azide to preparation of 1,4-disubstituted 1,2,3-triazoles with broad substrate scope and high yields. Carbon 21-22 protection of telomeres 1 Homo sapiens 108-113 33639933-2 2021 Methylenetetrahydrofolate reductase (MTHFR) gene is one of the genes in One Carbon Metabolic (OCM) pathway that affects both blood pressure and epigenetic phenomenon. Carbon 76-82 methylenetetrahydrofolate reductase Homo sapiens 37-42 35191441-4 2022 TC coated on glassy carbon (GC) exhibits a MOR current density of 38.38 A g-1 which is 2.9 times higher than that of Co3O4/GC in 1.5 M methanol at a 20 mV s-1 scan rate. Carbon 20-26 opioid receptor mu 1 Homo sapiens 43-46 27586456-1 2016 Sedoheptulose-1, 7-bisphosphatase (SBPase) is an important enzyme involved in photosynthetic carbon fixation in the Calvin cycle. Carbon 93-99 chloroplast sedoheptulose-1,7-bisphosphatase Solanum lycopersicum 35-41 26381241-2 2016 To investigate the intermolecular interaction and binding affinity between the EGF-conjugated DDS and the EGFR, 50 ns molecular dynamics simulations were performed on the complex of tethered EGFR and EGF linked to single-wall carbon nanotube (SWCNT) through a biopolymer chitosan wrapping the tube outer surface (EGFR EGF-CS-SWCNT-Drug complex), and compared to the EGFR EGF complex and free EGFR. Carbon 226-232 epidermal growth factor Homo sapiens 106-109 27573184-0 2016 Function of RSKS-1-AAK-2-DAF-16 signaling cascade in enhancing toxicity of multi-walled carbon nanotubes can be suppressed by mir-259 activation in Caenorhabditis elegans. Carbon 88-94 Fork-head domain-containing protein;Forkhead box protein O Caenorhabditis elegans 25-31 27354064-4 2016 IDH1 promotes the synthesis of lipids specifically from glutamine-derived carbons. Carbon 74-81 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 0-4 35235340-3 2022 We found that SERAC1 localizes to the outer mitochondrial membrane and is a protein component of the one-carbon cycle. Carbon 105-111 serine active site containing 1 Mus musculus 14-20 35235340-5 2022 Loss of SERAC1 impaired the one-carbon cycle and disrupted the balance of the nucleotide pool, which led to primary mitochondrial DNA (mtDNA) depletion in mice, HEK293T cells, and patient-derived immortalized lymphocyte cells due to insufficient supply of nucleotides. Carbon 32-38 serine active site containing 1 Mus musculus 8-14 27560137-2 2016 The MTHFR and TS protein were crucial factor in one-carbon metabolism. Carbon 52-58 thymidylate synthetase Homo sapiens 14-16 35112148-2 2022 The molecularly imprinted polymer (MIP)-based sensor (MA-Tyr@MIP/GCE) was prepared via photopolymerization on the glassy carbon electrode and subsequently characterized by using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FTIR). Carbon 121-127 aminomethyltransferase Homo sapiens 65-68 35269071-1 2022 Double strap lap adhesive joints between metal (AA 6061-T6) and composite (carbon/epoxy) laminates were fabricated and characterized based on strength. Carbon 75-81 LAP Homo sapiens 13-16 27286767-0 2016 A sol-gel derived pH-responsive bovine serum albumin molecularly imprinted poly(ionic liquids) on the surface of multiwall carbon nanotubes. Carbon 123-129 albumin Bos taurus 39-52 35268729-0 2022 Impact of Impure Gas on CO2 Capture from Flue Gas Using Carbon Nanotubes: A Molecular Simulation Study. Carbon 56-62 gastrin Homo sapiens 17-20 35268729-0 2022 Impact of Impure Gas on CO2 Capture from Flue Gas Using Carbon Nanotubes: A Molecular Simulation Study. Carbon 56-62 gastrin Homo sapiens 46-49 35268729-1 2022 We used a grand canonical Monte Carlo simulation to study the influence of impurities including water vapor, SO2, and O2 in the flue gas on the adsorption of CO2/N2 mixture in carbon nanotubes (CNTs) and carboxyl doped CNT arrays. Carbon 176-182 gastrin Homo sapiens 133-136 27261460-7 2016 Finally, using both co-immunoprecipitation and bimolecular fluorescence complementation, we demonstrated the interaction of Rod1 with Hxt6 and showed that the localization of the Rod1-Hxt6 complex at the plasma membrane is affected by carbon source and is reduced upon overexpression of SNF1 and BMH2. Carbon 235-241 14-3-3 family protein BMH2 Saccharomyces cerevisiae S288C 296-300 35107471-7 2022 The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of onion carbon dots against Pseudomonas fragi were 2 mg mL-1 and 4 mg mL-1, respectively. Carbon 101-107 L1 cell adhesion molecule Mus musculus 149-159 35107471-7 2022 The minimum inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of onion carbon dots against Pseudomonas fragi were 2 mg mL-1 and 4 mg mL-1, respectively. Carbon 101-107 L1 cell adhesion molecule Mus musculus 163-167 35174858-5 2022 Flag-PCSK9PH thus significantly enhanced cell-surface LDLR levels and the ability of LDLR to take up extracellular LDL-C. Carbon 118-120 proprotein convertase subtilisin/kexin type 9 Homo sapiens 5-10 35174858-5 2022 Flag-PCSK9PH thus significantly enhanced cell-surface LDLR levels and the ability of LDLR to take up extracellular LDL-C. Carbon 118-120 low density lipoprotein receptor Homo sapiens 85-89 27240266-2 2016 By applying this principle, we have developed a stable Pt1 single-atom catalyst with a high Pt loading (close to 1 wt %) on phosphomolybdic acid(PMA)-modified active carbon. Carbon 166-172 zinc finger protein 77 Homo sapiens 55-58 35214469-0 2022 Facile Synthesis of Polyaniline/Carbon-Coated Hollow Indium Oxide Nanofiber Composite with Highly Sensitive Ammonia Gas Sensor at the Room Temperature. Carbon 32-38 gastrin Homo sapiens 116-119 35214469-4 2022 The gas-sensing performances of the fabricated PANI/hollow C#In2O3 nanofiber composite sensor were estimated at room temperature, and the response value of the composite sensor with an exposure of 1 ppm NH3 was 18.2, which was about 5.74 times larger than that of the pure PANI sensor. Carbon 59-60 gastrin Homo sapiens 4-7 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 DNA methyltransferase 3 alpha Homo sapiens 133-139 35138533-0 2022 Removal of Cd2+ from water containing Ca2+ and Mg2+ using titanate nanotubes modified by carbon. Carbon 89-95 CD2 molecule Homo sapiens 11-14 35138533-9 2022 It indicates that the surface carbon modification can alleviate the hindrance of Ca2+ or Mg2+ to Cd2+ removal. Carbon 30-36 CD2 molecule Homo sapiens 97-100 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 DNA methyltransferase 3 beta Homo sapiens 145-151 35138533-10 2022 This is because the carbon on the surface of TNT captured part of Ca2+ or Mg2+; it made more Cd2+ be successfully absorbed by TNT through ion exchange. Carbon 20-26 CD2 molecule Homo sapiens 93-96 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 thymidylate synthetase Homo sapiens 262-266 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 dihydrofolate reductase Homo sapiens 268-272 27386562-7 2016 SHMT1 encodes a serine hydroxymethyltransferase catalyzing the transfer of a carbon unit to the folate cycle. Carbon 77-83 serine hydroxymethyltransferase 1 Homo sapiens 0-5 35109908-8 2022 LINC00461 was inversely correlated with the survival of mice-bearing GBM and it was stabilized by the interaction between HDAC6 and RNA-binding proteins (RBPs) such as carbon catabolite repression-negative on TATA-less (CCR4-NOT) core exoribonuclease subunit 6 and fused in sarcoma. Carbon 168-174 chemokine (C-C motif) receptor 4 Mus musculus 220-224 35016164-0 2022 Advancement in fabrication of carbon nanotube tip for atomic force microscope using multi-axis nanomanipulator in scanning electron microscope. Carbon 30-36 TOR signaling pathway regulator Homo sapiens 46-49 35016164-1 2022 We have constructed a new nanomanipulator (NM) in a field emission scanning electron microscope (FE-SEM) to fabricate carbon nanotube (CNT) tip to precisely adjust the length and attachment angle of CNT onto the mother atomic force microscope (AFM) tip. Carbon 118-124 TOR signaling pathway regulator Homo sapiens 140-143 27358718-7 2016 The combined network shows that glycolytic enzymes are linked to miRs via p53, c-MYC, HIF1alpha, whereas the genes in serine, glycine and one carbon metabolism are regulated via the c-MYC, as well as other regulatory organization that cannot be observed by investigating individual miRs, TFs, and target genes. Carbon 142-148 MYC proto-oncogene, bHLH transcription factor Homo sapiens 79-84 27358718-7 2016 The combined network shows that glycolytic enzymes are linked to miRs via p53, c-MYC, HIF1alpha, whereas the genes in serine, glycine and one carbon metabolism are regulated via the c-MYC, as well as other regulatory organization that cannot be observed by investigating individual miRs, TFs, and target genes. Carbon 142-148 MYC proto-oncogene, bHLH transcription factor Homo sapiens 182-187 35016164-1 2022 We have constructed a new nanomanipulator (NM) in a field emission scanning electron microscope (FE-SEM) to fabricate carbon nanotube (CNT) tip to precisely adjust the length and attachment angle of CNT onto the mother atomic force microscope (AFM) tip. Carbon 118-124 TOR signaling pathway regulator Homo sapiens 249-252 27019153-2 2016 It was used to make Mb-SGO-Nafion composite films by coating myoglobin (Mb) on the glassy carbon electrodes (GCE). Carbon 90-96 myoglobin Homo sapiens 20-22 35105101-0 2022 Tip-enhanced Raman spectroscopy of confined carbon chains. Carbon 44-50 TOR signaling pathway regulator Homo sapiens 0-3 27019153-2 2016 It was used to make Mb-SGO-Nafion composite films by coating myoglobin (Mb) on the glassy carbon electrodes (GCE). Carbon 90-96 myoglobin Homo sapiens 61-70 27019153-2 2016 It was used to make Mb-SGO-Nafion composite films by coating myoglobin (Mb) on the glassy carbon electrodes (GCE). Carbon 90-96 myoglobin Homo sapiens 72-74 35066672-0 2022 Carbon quantum dots-Annexin V probe: photoinduced electron transfer mechanism, phosphatidylserine detection, and apoptotic cell imaging. Carbon 0-6 annexin A5 Homo sapiens 20-29 26897095-8 2016 The presence of both silicon and multi walled carbon nano-tubes (CS3) in the hydroxyapatite coating induce more adherence of viable human mesenchymal stem cells in contrast to the HA coated samples with only silicon (CS2). Carbon 46-52 myozenin 3 Homo sapiens 65-68 35066672-1 2022 An annexin V-based probe is designed and fabricated using carbon quantum dot as highly stable and biocompatible fluorescent crystals for real-time fluorescence imaging of apoptotic cells. Carbon 58-64 annexin A5 Homo sapiens 3-12 35066672-2 2022 Carbon quantum dots were synthesized, characterized, and conjugated to annexin V. Carbon 0-6 annexin A5 Homo sapiens 71-80 35062637-10 2022 Drop casting of C-MWCNT/EDC-NHS/DAO/GA onto carbon screen-printed electrodes increased the surface roughness and wettability. Carbon 44-50 D-amino acid oxidase Homo sapiens 32-35 27035059-5 2016 The number of genes whose expression was altered by poly I:C treatment was greatly reduced in IFNAR(-/-) DC, including the majority of the downregulated gene expression program previously observed in wild-type (WT) DC. Carbon 59-60 interferon alpha and beta receptor subunit 1 Homo sapiens 94-99 35087551-0 2021 Turning the Knobs: The Impact of Post-translational Modifications on Carbon Metabolism. Carbon 69-75 solute carrier family 35 member G1 Homo sapiens 33-37 35087551-5 2021 This review explores the role of post-translational modifications (PTMs) in the modulation of carbon metabolism. Carbon 94-100 solute carrier family 35 member G1 Homo sapiens 33-37 27017606-9 2016 COT administration reduced lipid accumulation in the liver, ameliorated the pathological changes, and lessened liver injury, the levels of TG, TC, and non-HDL-C in plasma were decreased significantly, and COT led to a significant increase in plasma HDL-C and apolipoprotein A (apoA1). Carbon 0-1 mitogen-activated protein kinase kinase kinase 8 Mus musculus 205-208 34890518-5 2022 These Ni-Cu/Al-KCC-1 catalysts were used to promote the cracking of waste cooking oil model compound (WCOMC) to produce H2 and carbon nanotubes (CNTs), and the 10 wt% Ni-5 wt% Cu/Al-KCC-1 exhibited the highest catalytic activity. Carbon 127-133 solute carrier family 12 member 4 Homo sapiens 15-20 33355460-5 2021 We demonstrate, using STM break-junction technique, single-molecule heterojunction comprising Au-molecule-ITO and Au-molecule-carbon circuits. Carbon 126-132 sulfotransferase family 1A member 3 Homo sapiens 22-25 27203178-4 2016 Cell cycle-dependent changes in central carbon metabolism are controlled by the cyclin-dependent kinase (Cdk1), a major cell cycle regulator, and the metabolic regulator protein kinase A. Carbon 40-46 cyclin-dependent serine/threonine-protein kinase CDC28 Saccharomyces cerevisiae S288C 105-109 33672587-0 2021 Scavenger Receptor A1 Mediates the Uptake of Carboxylated and Pristine Multi-Walled Carbon Nanotubes Coated with Bovine Serum Albumin. Carbon 84-90 albumin Cricetulus griseus 120-133 27203178-5 2016 At the G1/S transition, Cdk1 phosphorylates and activates the enzyme Nth1, which funnels the storage carbohydrate trehalose into central carbon metabolism. Carbon 137-143 cyclin-dependent serine/threonine-protein kinase CDC28 Saccharomyces cerevisiae S288C 24-28 27203178-5 2016 At the G1/S transition, Cdk1 phosphorylates and activates the enzyme Nth1, which funnels the storage carbohydrate trehalose into central carbon metabolism. Carbon 137-143 alpha,alpha-trehalase NTH1 Saccharomyces cerevisiae S288C 69-73 33508196-1 2021 ConspectusTetracyclic diterpenoids (C20) mainly refer to the plant terpenoids bearing biogenetically related carbon skeletons derived from copalyl diphosphates (ent-CPP and syn-CPP). Carbon 109-115 synemin Homo sapiens 173-176 26774085-0 2016 A fluorescence resonance energy transfer (FRET) based "Turn-On" nanofluorescence sensor using a nitrogen-doped carbon dot-hexagonal cobalt oxyhydroxide nanosheet architecture and application to alpha-glucosidase inhibitor screening. Carbon 111-117 sucrase-isomaltase Homo sapiens 194-211 27274234-0 2016 Carbon nanospheres mediated delivery of nuclear matrix protein SMAR1 to direct experimental autoimmune encephalomyelitis in mice. Carbon 0-6 BTG3 associated nuclear protein Mus musculus 63-68 33644606-3 2021 In this study, we propose a freestanding flexible sensor electrode based on a beta-MnO2-decorated carbon nanofiber sheet (beta-MnO2@CNF) to detect dimethyl methylphosphonate (DMMP) as a nerve agent simulant. Carbon 98-104 NPHS1 adhesion molecule, nephrin Homo sapiens 132-135 33538010-0 2021 The Potential of Resilient Carbon Dynamics for Stabilising Crop Reproductive Development and Productivity During Heat Stress. Carbon 27-33 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 59-63 33538010-1 2021 Impaired carbon metabolism and reproductive development constrain crop productivity during heat stress. Carbon 9-15 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 66-70 33538010-5 2021 To this end, we review recent studies relating to source-sink dynamics, non-foliar photosynthesis and net carbon gain as pivotal in understanding how to improve reproductive development and crop productivity during heat stress. Carbon 106-112 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 190-194 27274234-2 2016 Here, we demonstrate a novel carbon nanosphere (CNP) based treatment regime for encephalomyelitis in mice by exploiting the functional property of the nuclear matrix binding protein SMAR1. Carbon 29-35 BTG3 associated nuclear protein Mus musculus 182-187 27280172-1 2016 A chemiresistive detector for carbon monoxide was created from single-walled carbon nanotubes (SWCNTs) by noncovalent modification with diiodo(eta5: eta1-1-[2-(N,N-dimethylamino)ethyl]-2,3,4,5-tetramethylcyclopentadienyl)-cobalt(III) ([Cp^CoI2]), an organocobalt complex with an intramolecular amino ligand coordinated to the metal center that is displaced upon CO binding. Carbon 30-36 secreted phosphoprotein 1 Homo sapiens 149-153 33495342-4 2021 Inhibition of miR-33 has also been shown to improve high-density lipoprotein (HDL) biogenesis in the liver and increase circulating HDL-C levels in both rodents and nonhuman primates. Carbon 135-137 microRNA 33 Mus musculus 14-20 32779873-1 2021 Mitochondrial serine hydroxymethyltransferase 2 (SHMT2) is an important drug target in the one-carbon metabolic pathway, since its activity is critical for purine and pyrimidine biosynthesis. Carbon 95-101 serine hydroxymethyltransferase 2 Homo sapiens 14-47 32779873-1 2021 Mitochondrial serine hydroxymethyltransferase 2 (SHMT2) is an important drug target in the one-carbon metabolic pathway, since its activity is critical for purine and pyrimidine biosynthesis. Carbon 95-101 serine hydroxymethyltransferase 2 Homo sapiens 49-54 26634234-5 2016 The X-ray structures of E-1a, E-1b and E-1c show a slightly shortened N-C bond to the alkene moieties. Carbon 72-73 small nucleolar RNA, H/ACA box 73B Homo sapiens 39-43 33260019-7 2021 LPS stimulation upregulated IL-10, IL-8, and IL-6 expression and Poly I:C upregulated TLR 8 and TLR 9 expression. Carbon 72-73 toll-like receptor 8 Bos taurus 86-91 27148479-8 2016 Flow cytometric analysis showed that carbon ion irradiation induced a permanent G2/M arrest in PC3 cells at lower doses (2 Gy) compared to X-rays (5 Gy), while in Caco-2 cells the G2/M arrest was transient after irradiation with X-rays (2 and 5 Gy) but persistent after exposure to carbon ions (2 Gy). Carbon 37-43 chromobox 8 Homo sapiens 95-98 31293221-1 2021 Sludge-based activated carbon (ZAC) was successfully employed as both adsorbent and catalyst for the oxidation process of reactive yellow 86 (RY86) and reactive black 5 (RB5). Carbon 23-29 PLAG1 like zinc finger 1 Homo sapiens 31-34 27092136-4 2016 MT2 microplates (Biolog(TM)) method is traditionally used for bacteria identification and the evaluation of their ability to utilize different carbon substrates. Carbon 143-149 metallothionein 2A Homo sapiens 0-3 33334897-5 2021 Ginsenoside-20(S)-Rg3, containing a disaccharide group (glucose-glucose) at carbon-3, displayed positive modulator activity with a reduced EC50 for ATP and increased maximal response at human P2X7. Carbon 76-82 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 Homo sapiens 0-21 33393533-1 2021 A facile and single-step nickel oxide-dispersed in situ grown 3-D graphitic forest engrained carbon foam (NiO-CNF-CF)-based electrode was fabricated for high-performance microbial fuel cells (MFCs). Carbon 93-99 NPHS1 adhesion molecule, nephrin Homo sapiens 110-113 26974599-2 2016 To date, information about the direct binding of FFAs to hGPR40 is very limited, and how carbon-chain length affects the activities of FFAs on hGPR40 is not yet understood. Carbon 89-95 free fatty acid receptor 1 Homo sapiens 143-149 33468252-7 2021 Gene expression analysis identified upregulation of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) to regulate one-carbon metabolism. Carbon 119-125 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 52-93 26974599-7 2016 The results showed that the binding potencies of FFAs to hGPR40 were dependent on carbon length. Carbon 82-88 free fatty acid receptor 1 Homo sapiens 57-63 33468252-7 2021 Gene expression analysis identified upregulation of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) to regulate one-carbon metabolism. Carbon 119-125 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 95-101 26873212-1 2016 A facile and effective approach of fabricating oxidized multiwalled carbon nanotube/glassy carbon electrode (OMWCNT/GCE) is herein reported. Carbon 68-74 aminomethyltransferase Homo sapiens 109-119 27079438-6 2016 Importantly, the combined adjuvant of poly(I:C) plus LAG-3-Ig downregulated expressions of PD-1, LAG-3, and TIGIT on P1A-specific T cells, indicating prevention of T cell exhaustion. Carbon 45-46 zinc finger protein 185 Mus musculus 117-120 33488657-6 2020 Using two near-isogeneic lines, differing solely around the ACD6 locus, we showed that ACD6 regulates rosette growth, leaf chlorophyll content, as well as leaf nitrogen and carbon percentages. Carbon 173-179 ankyrin repeat family protein Arabidopsis thaliana 87-91 33411826-2 2021 Dietary factors such as folic acid can affect epigenetic marks using methylenetetrahydrofolate reductase (MTHFR) to metabolize folic acid to a one-carbon methyl group. Carbon 147-153 methylenetetrahydrofolate reductase Homo sapiens 69-104 27011316-4 2016 Quantitative gene expression was analyzed and the gene function of BGL2 and BGL3 was confirmed by heterologous expression using cellobiose as a sole carbon source. Carbon 149-155 glucan 1,3-beta-glucosidase Saccharomyces cerevisiae S288C 67-71 33411826-2 2021 Dietary factors such as folic acid can affect epigenetic marks using methylenetetrahydrofolate reductase (MTHFR) to metabolize folic acid to a one-carbon methyl group. Carbon 147-153 methylenetetrahydrofolate reductase Homo sapiens 106-111 32383312-4 2021 Here we report that Cystathionine beta-synthase (CBS), a central enzyme in one-carbon metabolism, functionally interacts with the core circadian protein Cryptochrome1 (CRY1). Carbon 79-85 cryptochrome 1 (photolyase-like) Mus musculus 153-166 32383312-4 2021 Here we report that Cystathionine beta-synthase (CBS), a central enzyme in one-carbon metabolism, functionally interacts with the core circadian protein Cryptochrome1 (CRY1). Carbon 79-85 cryptochrome 1 (photolyase-like) Mus musculus 168-172 32383312-12 2021 We observed temporal variation in one-carbon and transsulfuration pathways attributable to CRY1 induced CBS activation. Carbon 38-44 cryptochrome 1 (photolyase-like) Mus musculus 91-95 26996892-4 2016 Moreover, Hxt11 and Hxt15 are capable of transporting xylitol, a five-carbon polyol derived from xylose, the most abundant pentose in lignocellulosic biomass. Carbon 70-76 hexose transporter HXT11 Saccharomyces cerevisiae S288C 10-15 33255057-0 2021 Fe3+ and intracellular pH determination based on orange fluorescence carbon dots co-doped with boron, nitrogen and sulfur. Carbon 69-75 l(2)FE3 Drosophila melanogaster 0-3 26989608-19 2016 ADH2 expression in L. fermentati may be subjected to changes in the presence of non-fermentative carbon source. Carbon 97-103 alcohol dehydrogenase ADH2 Saccharomyces cerevisiae S288C 0-4 33380425-0 2021 Disturbances in PP2A methylation and one-carbon metabolism compromise Fyn distribution, neuritogenesis and APP regulation. Carbon 41-47 Fyn proto-oncogene Mus musculus 70-73 33380425-12 2021 One-carbon metabolism also modulates Fyn-dependent process outgrowth in N2a cells. Carbon 4-10 Fyn proto-oncogene Mus musculus 37-40 33179677-5 2020 The interaction of SnIVCl2(TPP2-) with CN- is accompanied by the addition of CN- to the meso-carbon atom of porphyrin forming diamagnetic TPP(CN)3- macrocycles in {crypt(K+)}{SnIV(CN)2[TPP(CN)]3-}- (2). Carbon 93-99 tripeptidyl peptidase 2 Homo sapiens 27-31 32919620-3 2020 In this paper, we fabricated carbon nanofiber/gold nanoparticle (CNF/AuNP) conductive scaffolds using two distinct methods. Carbon 29-35 NPHS1 adhesion molecule, nephrin Homo sapiens 65-68 33260678-5 2020 The results showed that the MoS2-Au-Ag-modified glassy carbon electrode (GCE) has higher sensitivity (405.24 microA mM-1 cm-2), wider linear detection range (0.05-20 mM) and satisfactory repeatability and stability. Carbon 55-61 Mix1 homeobox-like 1 (Xenopus laevis) Mus musculus 116-125 33255463-0 2020 Development of a Novel Electrochemical Biosensor Based on Carbon Nanofibers-Gold Nanoparticles-Tyrosinase for the Detection of Ferulic Acid in Cosmetics. Carbon 58-64 tyrosinase Homo sapiens 95-105 33255463-2 2020 To prepare the biosensor, the tyrosinase (Ty) was immobilized on the surface of the electrode already modified with carbon nanofibers and gold nanoparticles, by the drop-and-dry technique. Carbon 116-122 tyrosinase Homo sapiens 30-40 33207837-4 2020 An integrative proteomic and metabolomic analysis indicates a rewiring of the central carbon metabolism, with an upregulation of the tricarboxylic acid (TCA) cycle and mitochondrial adenosine triphosphate (ATP) production in the presence of high methionine and AMP-activated protein kinase (AMPK) inhibition. Carbon 86-92 protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens 261-289 33207837-4 2020 An integrative proteomic and metabolomic analysis indicates a rewiring of the central carbon metabolism, with an upregulation of the tricarboxylic acid (TCA) cycle and mitochondrial adenosine triphosphate (ATP) production in the presence of high methionine and AMP-activated protein kinase (AMPK) inhibition. Carbon 86-92 protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens 291-295 33225168-8 2020 The spin-lattice relaxation time of carbon nuclei varies from 1 to 107 s. The range of molecular correlation time also varies from 10-4 to 10-8 s. These remarkable diversities of motional dynamics of the molecules imply that there exist various motional degrees of freedom within this valuable drug and these motional degrees of freedom are independent of each other, which may be the reason for the biological activities exhibited by the drug. Carbon 36-42 spindlin 1 Homo sapiens 4-8 33001250-11 2020 We have demonstrated that cra, crp, phoB, and phoR are involved in the regulation of central carbon metabolism. Carbon 93-99 catabolite gene activator protein Escherichia coli 31-34 32061118-6 2020 Hence, repression of co293 expression elevates the levels of HcaR and FadR with consequent activation of alternative carbon catabolic pathways. Carbon 117-123 DNA-binding transcriptional dual regulator HcaR Escherichia coli str. K-12 substr. MG1655 61-65 32604557-1 2020 In this paper, the relationship between the pore spatial structures, pore sizes, and pore types of highly ordered mesoporous CMK-based carbons (CMK-1, CMK-3, and CMK-5) and their electrochemical performance in Li-S batteries is investigated. Carbon 135-142 cytidine/uridine monophosphate kinase 1 Homo sapiens 125-128 32887167-2 2020 In this work, NiCo2S4 nanoneedle arrays grown on an electrospun graphitized carbon nanofiber film (NiCo2S4/GCNF) is successfully prepared by a simple two-step hydrothermal method, and further applied to detection of fungicide pyrimethanil (PMT). Carbon 76-82 nuclear receptor subfamily 6 group A member 1 Homo sapiens 107-111 33122714-2 2020 Pyrolysis of anthracene with cobalt complex Co(2,2"-bipy)Cl2 (1), where (2,2"-bipy) is 2,2"-bipyridine, in the absence and presence of silica gave in high yield cobalt-carbon nanocomposite CoCNC (2) and CoCNC@SiO2 (3) at 600 C and 850 C, respectively. Carbon 168-174 endogenous retrovirus group W member 5 Homo sapiens 57-60 33051300-7 2020 Disruption of both type-A ARRs and EXO70D1,2,3 compromised survival in carbon-deficient conditions, suggesting interaction between autophagy and cytokinin responsiveness in response to stress. Carbon 71-77 exocyst subunit exo70 family protein D1 Arabidopsis thaliana 35-42 33104522-5 2020 Ccl2 overexpression decreased the lifespan of the progeroid mice and induced the dysregulation of glycolysis, the citric acid cycle and one-carbon metabolism in skeletal muscle, driving dynamic changes in energy metabolism and DNA methylation. Carbon 140-146 chemokine (C-C motif) ligand 2 Mus musculus 0-4 26872251-6 2016 On the basis of these results, using trimethylsilyl derivatives TMS-X (X = OMe, SEt, NEt2) as the nucleophilic ligand source and the fluorine acceptor, catalytic transformation of the C-F bond of aromatic substrates to the C-X (X = O, S, N) bond was achieved with tBuXantphosAuCl as the catalyst (up to 20 turnover numbers). Carbon 184-185 tetraspanin 12 Homo sapiens 85-89 32263018-3 2016 This study demonstrated that conjugation of a corticosteroid (triamcinolone) on polyethylene-glycol (PEG)-fabricated multi-walled carbon nanotubes enhances intracellular drug delivery via increased lysosome transport and ultimately suppresses the expression of major pro-inflammatory cytokines (i.e., TNF-alpha, IL-1beta, and IL-6) and matrix metalloproteinase-1 and -3 from fibroblast-like synoviocytes at a very low drug dose. Carbon 130-136 interleukin 1 alpha Homo sapiens 312-320 32263018-3 2016 This study demonstrated that conjugation of a corticosteroid (triamcinolone) on polyethylene-glycol (PEG)-fabricated multi-walled carbon nanotubes enhances intracellular drug delivery via increased lysosome transport and ultimately suppresses the expression of major pro-inflammatory cytokines (i.e., TNF-alpha, IL-1beta, and IL-6) and matrix metalloproteinase-1 and -3 from fibroblast-like synoviocytes at a very low drug dose. Carbon 130-136 matrix metallopeptidase 1 Homo sapiens 336-369 27013776-3 2016 To be used, folic acid must be converted to 7,8-dihydrofolate by dihydrofolate reductase to generate one-carbon derivatives serving as important cellular cofactors in the synthesis of nucleotides and amino acids required for cell growth. Carbon 105-111 dihydrofolate reductase Homo sapiens 65-88 26895662-8 2016 In both the FPGS-overexpressed HCT116 and MDA-MB-435 cell lines, we identified several differentially expressed genes involved in folate biosynthesis and one-carbon metabolism, which might in part have contributed to the observed increased efficacy of 5-fluorouracil in response to FPGS overexpression. Carbon 158-164 folylpolyglutamate synthase Homo sapiens 12-16 27476207-5 2016 Microbial communities of the Kara Sea shelf and Yenisei Gulf sediments were found to contain the organisms capable of utilization of a broad spectrum of carbon sources, including gaseous and petroleum hydrocarbons. Carbon 153-159 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 34-37 26842424-3 2016 The stereogenic carbons were elaborated by desymmetrization for C12, allylation for C13, vanadyl-induced epoxidation for C16, Zn(BH4)2 reduction for C17, a chiral building block for C18 and C24, Shi epoxidation for C20 and C21, Myers" alkylation for C22, and thermodynamic control for C25. Carbon 16-23 cytokine like 1 Homo sapiens 149-152 26674684-4 2016 Here we present INCA-Contaminants, the Integrated Catchments model for Contaminants; a new model that simultaneously and realistically solves mass balances of water, carbon, sediments and contaminants in the soil-stream-sediment system of catchments and their river networks as a function of climate, land use/management and contaminant properties. Carbon 166-172 caspase recruitment domain family member 17 Homo sapiens 16-20 33095157-5 2020 We found that activated murine CD8+ T cells alter their central carbon metabolism in response to exertion in vivo, and that immune cells from trained mice are more potent antitumor effector cells when transferred into tumor-bearing untrained animals. Carbon 64-70 CD8a molecule Homo sapiens 31-34 33081078-0 2020 Effect of Sand Fines Concentration on the Erosion-Corrosion Mechanism of Carbon Steel 90 Elbow Pipe in Slug Flow. Carbon 73-79 snail family transcriptional repressor 2 Homo sapiens 104-108 33081078-2 2020 The carbon steel 90 elbows are susceptible to the erosion-corrosion during the multiphase flow, peculiarly for erosive slug flows. Carbon 4-10 snail family transcriptional repressor 2 Homo sapiens 120-124 26752460-3 2016 Under the optimal OFA damper opening (i.e, 55%), NOx emissions and carbon in fly ash attained levels of 589 mg/m(3) at 6% O2 and 6.18%, respectively, achieving NOx and carbon in fly ash significant reduction by 33% and 37%, respectively. Carbon 67-73 NADPH oxidase Drosophila melanogaster 160-163 32738413-5 2020 The most important structural modification leading to increased inhibitory activity towards both COXs and 5-LOX was the elongation of alkyl chain in position 6 from 5 to 11 carbons. Carbon 173-180 lysyl oxidase Homo sapiens 108-111 26752460-3 2016 Under the optimal OFA damper opening (i.e, 55%), NOx emissions and carbon in fly ash attained levels of 589 mg/m(3) at 6% O2 and 6.18%, respectively, achieving NOx and carbon in fly ash significant reduction by 33% and 37%, respectively. Carbon 168-174 NADPH oxidase Drosophila melanogaster 49-52 32729532-2 2020 By combining Poly (3,4-ethylenedioxythiophene) (PEDOT), with Carbon Nanofibers (CNFs), we demonstrate a versatile approach for the synthesis of a novel composite material PEDOT:CNF with remarkable electrochemical properties, combining low impedance, high surface area, high charge injection capability and reliable neurotransmitters monitoring using amperometric techniques. Carbon 61-67 NPHS1 adhesion molecule, nephrin Homo sapiens 80-83 26652440-2 2016 The ZnO nanoparticles and multi-walled carbon nanotubes modified CPE (ZnO-MWCNT/CPE) electrode was prepared by incorporation of the ZnO nanoparticles and multi-walled carbon nanotubes (MWCNT) in carbon paste electrode. Carbon 39-45 carboxypeptidase E Homo sapiens 65-68 33014705-8 2020 The best operation conditions consisted on using un-meshed vegetable AC, without acid pretreatment in an EF reactor loaded with 0.25 g of Fe, which allowed to reach full color removal of bright blue FCP model dye in 70 min. Carbon 69-71 FCP1 Homo sapiens 199-202 32975743-3 2020 WRINKLED1 (WRI1) is one of the important transcription factors which regulate the fatty acid biosynthesis network and TAG accumulation by balancing carbon flux between carbohydrates and lipids. Carbon 148-154 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 11-15 26652440-2 2016 The ZnO nanoparticles and multi-walled carbon nanotubes modified CPE (ZnO-MWCNT/CPE) electrode was prepared by incorporation of the ZnO nanoparticles and multi-walled carbon nanotubes (MWCNT) in carbon paste electrode. Carbon 39-45 carboxypeptidase E Homo sapiens 70-83 26652440-2 2016 The ZnO nanoparticles and multi-walled carbon nanotubes modified CPE (ZnO-MWCNT/CPE) electrode was prepared by incorporation of the ZnO nanoparticles and multi-walled carbon nanotubes (MWCNT) in carbon paste electrode. Carbon 167-173 carboxypeptidase E Homo sapiens 65-68 26652440-2 2016 The ZnO nanoparticles and multi-walled carbon nanotubes modified CPE (ZnO-MWCNT/CPE) electrode was prepared by incorporation of the ZnO nanoparticles and multi-walled carbon nanotubes (MWCNT) in carbon paste electrode. Carbon 167-173 carboxypeptidase E Homo sapiens 70-83 26652440-2 2016 The ZnO nanoparticles and multi-walled carbon nanotubes modified CPE (ZnO-MWCNT/CPE) electrode was prepared by incorporation of the ZnO nanoparticles and multi-walled carbon nanotubes (MWCNT) in carbon paste electrode. Carbon 167-173 carboxypeptidase E Homo sapiens 65-68 26652440-2 2016 The ZnO nanoparticles and multi-walled carbon nanotubes modified CPE (ZnO-MWCNT/CPE) electrode was prepared by incorporation of the ZnO nanoparticles and multi-walled carbon nanotubes (MWCNT) in carbon paste electrode. Carbon 167-173 carboxypeptidase E Homo sapiens 70-83 32819099-2 2020 The paramagnetic 13C Knight shift of alkyl chain carbons, which is proportional to the local electron spin density, exhibits an electron spin delocalization that exponentially decays along the alkyl chain. Carbon 49-56 spindlin 1 Homo sapiens 102-106 26651534-0 2016 On an Easy Way To Prepare Metal-Nitrogen Doped Carbon with Exclusive Presence of MeN4-type Sites Active for the ORR. Carbon 47-53 cyclin dependent kinase inhibitor 1B Homo sapiens 81-85 32819099-2 2020 The paramagnetic 13C Knight shift of alkyl chain carbons, which is proportional to the local electron spin density, exhibits an electron spin delocalization that exponentially decays along the alkyl chain. Carbon 49-56 spindlin 1 Homo sapiens 137-141 26651534-5 2016 Such catalysts reveal the desired homogeneous composition of MeN4 (Me = metal) sites in the carbon that is accompanied by a significant enhancement in ORR activity. Carbon 92-98 cyclin dependent kinase inhibitor 1B Homo sapiens 61-65 32408161-3 2020 Herein, necklace-like Fe3O4/carbon nanofibril aerogel (Fe3O4/CNF) was constructed by crosslinking alginate with Fe3+, followed by carbonization of the obtained ferric alginate aerogel. Carbon 28-34 NPHS1 adhesion molecule, nephrin Homo sapiens 61-64 26742069-2 2016 In this study, we investigated the effect of PPAR activation on circulating and urinary one-carbon metabolites as well as markers of B-vitamin status. Carbon 92-98 peroxisome proliferator activated receptor alpha Rattus norvegicus 45-49 32916888-0 2020 TinO2n-1 Suboxide Phases in TiO2/C Nanocomposites Engineered by Non-hydrolytic Sol-Gel with Enhanced Electrocatalytic Properties. Carbon 33-34 mex-3 RNA binding family member D Homo sapiens 0-4 31907296-7 2020 ROS1 fusions were identified in 8 IHCA, involving C-terminal part of genes highly expressed in the liver (PLG, RBP4, APOB) fused with exon 33-35 to 43 of ROS1 including the tyrosine kinase domain. Carbon 36-37 ROS proto-oncogene 1, receptor tyrosine kinase Homo sapiens 0-4 26653442-3 2016 A nanohybrid surface assembled onto a glassy carbon electrode consisting of amino carbon nanotubes recovered by hyaluronic acid was used as sensing platform to detect the anti-HBc. Carbon 45-51 keratin 88, pseudogene Homo sapiens 176-179 33241407-0 2020 A Green, Economic "Switch-On" Sensor for Cefixime Analysis Based on Black Soya Bean Carbon Quantum Dots. Carbon 84-90 brain expressed associated with NEDD4 1 Homo sapiens 79-83 33241407-4 2020 METHODS: In this study, black soya beans were used as an inexpensive carbon source for a "green" synthesis of fluorescent black soya bean (BS)-carbon quantum dots (CQDs). Carbon 69-75 brain expressed associated with NEDD4 1 Homo sapiens 35-39 26653442-3 2016 A nanohybrid surface assembled onto a glassy carbon electrode consisting of amino carbon nanotubes recovered by hyaluronic acid was used as sensing platform to detect the anti-HBc. Carbon 82-88 keratin 88, pseudogene Homo sapiens 176-179 33241407-4 2020 METHODS: In this study, black soya beans were used as an inexpensive carbon source for a "green" synthesis of fluorescent black soya bean (BS)-carbon quantum dots (CQDs). Carbon 143-149 brain expressed associated with NEDD4 1 Homo sapiens 35-39 26653442-9 2016 The enhancement of the hyaluronic acid by carbon nanotube promoted an increase of charge electron transfer, besides a stable platform for HBc. Carbon 42-48 keratin 88, pseudogene Homo sapiens 138-141 32498886-0 2020 Red-emission hydrophobic porphyrin structure carbon dots linked with transferrin for cell imaging. Carbon 45-51 transferrin Mus musculus 69-80 26642257-0 2015 Ultrafine CoP Nanoparticles Supported on Carbon Nanotubes as Highly Active Electrocatalyst for Both Oxygen and Hydrogen Evolution in Basic Media. Carbon 41-47 caspase recruitment domain family member 16 Homo sapiens 10-13 32498890-0 2020 Selective determination of DNA based on the fluorescence recovery of carbon dots quenched by Ru(bpy)2(dppz)2. Carbon 69-75 basic charge Y-linked 2 Homo sapiens 93-101 32498890-1 2020 A quick, highly selective and sensitive method for the determination of DNA was constructed based on the recovery of red fluorescence of carbon dots quenched by a ruthenium complex (Ru (bpy)2 (dppz)2+, bpy = 2,2"-bipyridine; dppz = dipyrido [3.2-a:2",3"-c]phenazine). Carbon 137-143 basic charge Y-linked 2 Homo sapiens 182-191 32498890-3 2020 After addition of Ru (bpy)2 (dppz)2+, the fluorescence of carbon dots at 683 nm was markedly quenched. Carbon 58-64 basic charge Y-linked 2 Homo sapiens 18-27 32747534-1 2020 Carbon and nitrogen isotope ratios in hair sampled from 65 communities across the central and intermountain regions of the United States and more intensively throughout 29 ZIP codes in the Salt Lake Valley, Utah, revealed a dietary divergence related to socioeconomic status as measured by cost of living, household income, and adjusted gross income. Carbon 0-6 death associated protein kinase 3 Homo sapiens 172-175 26675747-3 2015 H2O and CO2 delivered to the CMB by subducting slabs provide a source for hydrogen and carbon. Carbon 87-93 complement C2 Homo sapiens 0-11 32796716-0 2020 Sirt1-PPARS Cross-Talk in Complex Metabolic Diseases and Inherited Disorders of the One Carbon Metabolism. Carbon 88-94 sirtuin 1 Homo sapiens 0-5 26667181-2 2015 DNMT3B RNAi increased the sensitivity of HeLa, A549 and HCT116 cells to both gamma-irradiation and carbon-ion beam irradiation. Carbon 99-105 DNA methyltransferase 3 beta Homo sapiens 0-6 32905515-6 2020 Carbon-ion beam combined with lapatinib significantly enhanced apoptosis and carbon-ion beam alone dose-dependently increased autophagy-related expression of Beclin1 and in combination with lapatinib greatly enhanced ATG7 expression at protein levels. Carbon 77-83 beclin 1 Homo sapiens 158-165 32737440-1 2020 This study is the first report on the preparation of mesoporous carbon/silica (MCS) nanocomposites with tunable mesoporosity and hydrophobicity using natural rubber (NR) as a renewable and cheap carbon source. Carbon 64-70 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 79-82 26666829-1 2015 BACKGROUND: Serine hydroxymethyltransferase 1 (SHMT1) is a key enzyme in the folate metabolic pathway that plays an important role in biosynthesis by providing one carbon unit. Carbon 164-170 serine hydroxymethyltransferase 1 Homo sapiens 12-45 32737440-1 2020 This study is the first report on the preparation of mesoporous carbon/silica (MCS) nanocomposites with tunable mesoporosity and hydrophobicity using natural rubber (NR) as a renewable and cheap carbon source. Carbon 195-201 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 79-82 32737440-6 2020 The carbon content of MCS (3.0-16.1 wt%) was increased with an increase in the H2SO4 concentration. Carbon 4-10 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 22-25 32737440-8 2020 The enhanced hydrophobicity of MCS nanocomposites was related to the carbon content and the depletion of surface silanol groups, as confirmed by the water sorption measurement. Carbon 69-75 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 31-34 26666829-1 2015 BACKGROUND: Serine hydroxymethyltransferase 1 (SHMT1) is a key enzyme in the folate metabolic pathway that plays an important role in biosynthesis by providing one carbon unit. Carbon 164-170 serine hydroxymethyltransferase 1 Homo sapiens 47-52 26517817-1 2015 A new and sensitive voltammetric sensor for palmatine, based on an electrochemically reduced L-methionine functionalized graphene oxide modified glassy carbon electrode (L-Met-ERGO/GCE), is reported. Carbon 152-158 aminomethyltransferase Homo sapiens 181-184 32789172-0 2020 Giant spin signals in chemically functionalized multiwall carbon nanotubes. Carbon 58-64 spindlin 1 Homo sapiens 6-10 32789172-5 2020 Second, the spin information is brought toward the conducting inner shells of a multiwall carbon nanotube used as a confined nanoguide benefiting from both weak spin-orbit and hyperfine interactions. Carbon 90-96 spindlin 1 Homo sapiens 12-16 32789172-5 2020 Second, the spin information is brought toward the conducting inner shells of a multiwall carbon nanotube used as a confined nanoguide benefiting from both weak spin-orbit and hyperfine interactions. Carbon 90-96 spindlin 1 Homo sapiens 161-165 32644783-7 2020 In general, the cleavage mechanism of double C-C bond catalyzed by LcpK30 is similar to those of indoleamine 2,3-dioxygenase, tryptophan 2,3-dioxygenase, and the nonheme stilbene cleavage oxygenase NOV1 that all depend on the iron-bound dioxygen to initiate the cleavage reaction. Carbon 45-46 tryptophan 2,3-dioxygenase Homo sapiens 126-152 32644783-7 2020 In general, the cleavage mechanism of double C-C bond catalyzed by LcpK30 is similar to those of indoleamine 2,3-dioxygenase, tryptophan 2,3-dioxygenase, and the nonheme stilbene cleavage oxygenase NOV1 that all depend on the iron-bound dioxygen to initiate the cleavage reaction. Carbon 45-46 chromosome 11 putative open reading frame 40 Homo sapiens 198-202 26565933-2 2015 The crystalline sample (NaK-D-1) of the water-soluble, mixed sodium/potassium salt of D-1 was obtained in the 14.7% yield, which has been characterized by complete elemental analysis, TG/DTA, FTIR, single-crystal X-ray structure analysis, and solution ((183)W, (31)P, (1)H and (13)C{(1)H}) NMR spectroscopy. Carbon 281-282 TANK binding kinase 1 Homo sapiens 24-27 32644783-7 2020 In general, the cleavage mechanism of double C-C bond catalyzed by LcpK30 is similar to those of indoleamine 2,3-dioxygenase, tryptophan 2,3-dioxygenase, and the nonheme stilbene cleavage oxygenase NOV1 that all depend on the iron-bound dioxygen to initiate the cleavage reaction. Carbon 47-48 tryptophan 2,3-dioxygenase Homo sapiens 126-152 32644783-7 2020 In general, the cleavage mechanism of double C-C bond catalyzed by LcpK30 is similar to those of indoleamine 2,3-dioxygenase, tryptophan 2,3-dioxygenase, and the nonheme stilbene cleavage oxygenase NOV1 that all depend on the iron-bound dioxygen to initiate the cleavage reaction. Carbon 47-48 chromosome 11 putative open reading frame 40 Homo sapiens 198-202 26631379-5 2015 Like its human counterpart, the Lst7/Lst4 complex relocates to the vacuolar membrane in response to nutrient starvation, most notably in carbon starvation. Carbon 137-143 Lst4p Saccharomyces cerevisiae S288C 37-41 32664606-0 2020 Linkage between Carbon Metabolism, Redox Status and Cellular Physiology in the Yeast Saccharomyces cerevisiae Devoid of SOD1 or SOD2 Gene. Carbon 16-22 superoxide dismutase SOD2 Saccharomyces cerevisiae S288C 128-132 32196937-4 2020 Here, Znf1 was first shown to activate key genes in glycolysis, pyruvate metabolism and alcoholic fermentation when glucose is provided as the sole carbon source. Carbon 148-154 DNA-binding domain containing protein Saccharomyces cerevisiae S288C 6-10 25498140-3 2015 The carbon tip consists of concentric carbon layers in the shape of a cone, and has been previously studied as a very good candidate for cold field emission. Carbon 4-10 TOR signaling pathway regulator Homo sapiens 11-14 25498140-3 2015 The carbon tip consists of concentric carbon layers in the shape of a cone, and has been previously studied as a very good candidate for cold field emission. Carbon 38-44 TOR signaling pathway regulator Homo sapiens 11-14 27022467-8 2015 DGAT1 inhibition leads to enhancement of carbon flow to the synthesis of phosphatidylcholine within the intestine. Carbon 41-47 diacylglycerol O-acyltransferase 1 Mus musculus 0-5 26169151-0 2015 Innate immune humoral factors, C1q and factor H, with differential pattern recognition properties, alter macrophage response to carbon nanotubes. Carbon 128-134 complement C1q A chain Homo sapiens 31-34 26722253-0 2015 Inhibition of DNA-PKcs enhances radiosensitivity and increases the levels of ATM and ATR in NSCLC cells exposed to carbon ion irradiation. Carbon 115-121 ATM serine/threonine kinase Homo sapiens 77-80 26722253-7 2015 The expression levels of ATM, ATR, DNA-PKcs and phosphorylated histone H2AX, a biomarker for DNA double-strand breaks, were all upregulated at the transcriptional or translational level in A549 cells treated with carbon ion irradiation, compared with the control and X-rays-treated cells. Carbon 213-219 ATM serine/threonine kinase Homo sapiens 25-28 26418366-3 2015 Reducing the air gap is less important for scanning carbon ions, but ripple filters are still necessary for scanning carbon ion beams to reduce the number of energy steps required to deliver homogeneous SOBP. Carbon 117-123 sine oculis binding protein homolog Homo sapiens 203-207 26438849-4 2015 Here we report the identification of an Sptssb mutation, Stellar (Stl), which increased the SPT affinity toward the C18 fatty acyl-CoA substrate by twofold and significantly elevated 20-carbon (C20) LCB production in the mutant mouse brain and eye, resulting in surprising neurodegenerative effects including aberrant membrane structures, accumulation of ubiquitinated proteins on membranes, and axon degeneration. Carbon 186-192 serine palmitoyltransferase, small subunit B Mus musculus 40-46 26471447-8 2015 In addition, the reaction of hydrochloric salts of the carbones with Ag2 O gives the corresponding Ag(I) complexes. Carbon 55-63 anterior gradient 2, protein disulphide isomerase family member Homo sapiens 69-72 26445009-1 2015 Three stereoisomeric inhibitors of Pin1: (2R,5S)-, (2S,5R)- and (2S,5S)-Ac-pSer-Psi[(Z)CH = C]-pipecolyl(Pip)-2-(2-naphthyl)ethylamine 1, that mimic L-pSer-D-Pro, D-pSer-L-Pro, and D-pSer-D-Pro amides respectively, were synthesized by a 13-step route. Carbon 87-88 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens 35-39 26440109-5 2015 Among those Cat8 and Sip4 have overlapping DNA-binding specificity for so-called carbon source responsive elements and induce target genes upon SNF1 activation. Carbon 81-87 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 12-16 26440109-6 2015 To analyze the evolution of the Cat8-Sip4 controlled transcriptional network we have compared the response to carbon limitation of Saccharomyces cerevisiae to that of Kluyveromyces lactis. Carbon 110-116 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 32-36 26260787-7 2015 Coq6 is thus a rare example of a flavin monooxygenase that is able to act on two different carbon atoms of its C4-aminated substrate, allowing its deamination and ultimately its conversion into coenzyme Q by the other proteins constituting the coenzyme Q biosynthetic pathway. Carbon 91-97 putative N,N-dimethylaniline monooxygenase COQ6 Saccharomyces cerevisiae S288C 0-4 26290611-2 2015 ACBD6 binds acyl-CoAs of a chain length of 6 to 20 carbons. Carbon 51-58 acyl-CoA binding domain containing 6 Homo sapiens 0-5 26717702-14 2015 Erosion effect on source and sink of carbon emission was correlated with SOC content of the eroded sloping land. Carbon 37-43 UBX domain protein 11 Homo sapiens 73-76 26717702-17 2015 erosion tended to be a carbon sequestration process, and when SOC content was lower than 3.03 g.kg-1, the slope erosion tended to be a process of the carbon emission source. Carbon 150-156 UBX domain protein 11 Homo sapiens 62-65 25841119-0 2015 Ultrasensitive electrochemical detection of microRNA-21 combining layered nanostructure of oxidized single-walled carbon nanotubes and nanodiamonds by hybridization chain reaction. Carbon 114-120 microRNA 21 Homo sapiens 44-55 25841119-2 2015 In this study, we developed an electrochemical assay to detect miRNA-21 by fabricating the electrode with layer-by-layer assembly of oxidized single-walled carbon nanotubes and nanodiamonds. Carbon 156-162 microRNA 21 Homo sapiens 63-71 26253003-9 2015 The non-synonymous mutations in HXT2 and CIT1 may function in the presence of mutated MTH1 alleles and could be related to an altered central carbon metabolism in order to ensure production of cytosolic acetyl-CoA in the Pdc negative strain. Carbon 142-148 Mth1p Saccharomyces cerevisiae S288C 86-90 26140935-2 2015 Adsorption of ceruloplasmin (Cp) at a gold electrode modified with ferromagnetic iron nanoparticles encapsulated in carbon (Fe@C Nps) leads to a successful immobilization of the enzyme in its electroactive form. Carbon 116-122 ceruloplasmin Homo sapiens 14-27 31876382-5 2020 In spite of structural similarity, the two proteins catalyse distinct chemical reactions; SnoK is a C2-C5"" carbocyclase, whereas SnoN catalyses stereoinversion at the adjacent C4"" position. Carbon 100-107 SKI like proto-oncogene Homo sapiens 130-134 31876382-7 2020 Our analyses indicate that the carbocyclase SnoK is the ancestral form of the enzyme from which SnoN has evolved to catalyse stereoinversion at the neighboring carbon. Carbon 160-166 SKI like proto-oncogene Homo sapiens 96-100 25982115-5 2015 We propose that SCF(Ucc1)-mediated regulation of citrate synthase acts as a metabolic switch for the glyoxylate cycle in response to changes in carbon source, thereby ensuring metabolic versatility and flexibility. Carbon 144-150 ependymin related 1 Homo sapiens 20-24 32379616-1 2020 BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is the key enzyme of folate metabolism in the process of one-carbon cycle and its deficiency results in elevated homocysteine concentration. Carbon 117-123 methylenetetrahydrofolate reductase Homo sapiens 12-47 25899780-5 2015 The mild activated N-doped carbon microflowers (A-NCF-4) have a hierarchically porous structure, high specific surface area (2309 m(2) g(-1)), desirable micropore size below 1 nm, and importantly large micropore volume (0.95 cm(3) g(-1)). Carbon 27-33 neutrophil cytosolic factor 4 Homo sapiens 50-55 32379616-1 2020 BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is the key enzyme of folate metabolism in the process of one-carbon cycle and its deficiency results in elevated homocysteine concentration. Carbon 117-123 methylenetetrahydrofolate reductase Homo sapiens 49-54 32315286-4 2020 Extracellular flux and carbon tracing analyses revealed that HDAC inhibitors blunted glycolysis in a c-Myc dependent manner accompanied by lower ATP levels. Carbon 23-29 histone deacetylase 9 Homo sapiens 61-65 25648260-4 2015 Cross-talk was observed between one-carbon and xenobiotic pathways in breast cancer (RFC 80 G>A, COMT H108L and TYMS 5"-UTR 28 bp tandem repeat) and SLE (CYP1A1 m1, MTRR 66 A>G and GSTT1). Carbon 36-42 thymidylate synthetase Homo sapiens 112-116 32504419-3 2020 By using a previously established mouse model of depression induced by combined delivery of IFN-alpha and polyinosinic:polycytidylic acid (poly(I:C)), a TLR3 agonist, we provide evidence that IFN-alpha and poly(I:C) reduce apical dendritic spine density in the hippocampal CA1 area ex vivo via mechanisms involving decreased TrkB signaling. Carbon 146-147 interferon alpha Mus musculus 192-201 25648260-4 2015 Cross-talk was observed between one-carbon and xenobiotic pathways in breast cancer (RFC 80 G>A, COMT H108L and TYMS 5"-UTR 28 bp tandem repeat) and SLE (CYP1A1 m1, MTRR 66 A>G and GSTT1). Carbon 36-42 cytochrome P450 family 1 subfamily A member 1 Homo sapiens 154-160 31975181-6 2020 Parathyroid hormone (PTH) was low-normal at 1.7 pmol/L, C-terminal fibroblast growth factor 23 (FGF23) was high at 293 RU/ml, but tubular maximum reabsorption of phosphate (TmPO4/GFR) was elevated at 1.93 mmol/L. Carbon 56-57 fibroblast growth factor 23 Homo sapiens 67-94 31975181-6 2020 Parathyroid hormone (PTH) was low-normal at 1.7 pmol/L, C-terminal fibroblast growth factor 23 (FGF23) was high at 293 RU/ml, but tubular maximum reabsorption of phosphate (TmPO4/GFR) was elevated at 1.93 mmol/L. Carbon 56-57 fibroblast growth factor 23 Homo sapiens 96-101 32022382-3 2020 RESULTS: In this project, 20 novel pyridine sulfide derivatives containing SDH-based heterocyclic amide fungicide were designed, synthesized, and characterized by proton nuclear magnetic resonance (1 H-NMR), carbon-13 (13 C)-NMR and high-resolution mass spectrometry (HRMS). Carbon 208-214 succinate dehydrogenase Solanum lycopersicum 75-78 25679118-1 2015 A novel magneto multiwalled carbon nanotube/carbon paste electrode (MMW/CPE) for the determination of mefenamic acid (MFA) was introduced. Carbon 28-34 carboxypeptidase E Homo sapiens 72-75 32606291-0 2020 A highly sensitive uric acid electrochemical biosensor based on a nano-cube cuprous oxide/ferrocene/uricase modified glassy carbon electrode. Carbon 124-130 urate oxidase (pseudogene) Homo sapiens 100-107 32606291-1 2020 A uric acid (UA) electrochemical biosensor was constructed using ferrocene (Fc) decorated cuprous oxide (Cu2O) enhanced electro-active characteristics and covalently immobilized with uricase (UOx) on glassy carbon electrode (GCE). Carbon 207-213 urate oxidase (pseudogene) Homo sapiens 183-190 32606291-1 2020 A uric acid (UA) electrochemical biosensor was constructed using ferrocene (Fc) decorated cuprous oxide (Cu2O) enhanced electro-active characteristics and covalently immobilized with uricase (UOx) on glassy carbon electrode (GCE). Carbon 207-213 urate oxidase (pseudogene) Homo sapiens 192-195 25679118-1 2015 A novel magneto multiwalled carbon nanotube/carbon paste electrode (MMW/CPE) for the determination of mefenamic acid (MFA) was introduced. Carbon 44-50 carboxypeptidase E Homo sapiens 72-75 26115297-13 2015 Tasco increased (P <= 0.001) SFA/PUFA in all tissues, whereas concentrations of CLA c-9, t-11 were greatest with SO in all tissues (P <= 0.02), compared to other diets. Carbon 3-4 PUFA Ovis aries 36-40 32545597-1 2020 The interaction of the alternative oxidase (AOX) pathway with nutrient metabolism is important for understanding how respiration modulates ATP synthesis and carbon economy in plants under nutrient deficiency. Carbon 157-163 acyl-CoA oxidase 1 Homo sapiens 23-42 32545597-1 2020 The interaction of the alternative oxidase (AOX) pathway with nutrient metabolism is important for understanding how respiration modulates ATP synthesis and carbon economy in plants under nutrient deficiency. Carbon 157-163 acyl-CoA oxidase 1 Homo sapiens 44-47 32193076-7 2020 In addition, ozone combining biological activated carbon (BAC) or other advanced oxidation processes (AOPs) is also discussed, aiming to further improve mineralization of ozone-recalcitrant substances in NF/RO concentrate. Carbon 50-56 neurofascin Homo sapiens 204-209 25845933-1 2015 Novel 16-triazoles in the 13alpha-estrone series were synthesized via Cu(I)-catalyzed azide-alkyne cycloaddition of the two diastereomeric (on C-16 and on C-17) 16-azido-13alpha-estra-1,3,5(10)-trien-17-ol 3-benzyl ethers with substituted phenylacetylenes. Carbon 70-71 cytokine like 1 Homo sapiens 155-159 32293784-3 2020 The kinetic studies evidenced SN2 mechanism for both alkylation steps, yielding mono- and dialkylated C60(CF2), respectively, and indicated the negative charge localization at the bridgehead carbon atoms as well as a steric hindrance of the CF2 moiety likely to be a key factors for the S N 2 reaction mechanism and observed regioselectivity. Carbon 191-197 ATPase H+ transporting accessory protein 1 Homo sapiens 106-109 25854197-0 2015 Magnetic/NIR-responsive drug carrier, multicolor cell imaging, and enhanced photothermal therapy of gold capped magnetite-fluorescent carbon hybrid nanoparticles. Carbon 134-140 NOC2 like nucleolar associated transcriptional repressor Mus musculus 9-12 32393056-2 2020 The present study aims to investigate if common polymorphisms of genes required for one-carbon metabolism (MTHFR, MTRR, MTR and RFC-1) and DNA methylation reactions (DNMT1, DNMT3A and DNMT3B) influence D-loop methylation levels. Carbon 88-94 methylenetetrahydrofolate reductase Homo sapiens 107-112 32393056-2 2020 The present study aims to investigate if common polymorphisms of genes required for one-carbon metabolism (MTHFR, MTRR, MTR and RFC-1) and DNA methylation reactions (DNMT1, DNMT3A and DNMT3B) influence D-loop methylation levels. Carbon 88-94 replication factor C subunit 1 Homo sapiens 128-133 32841189-13 2020 There was a significant decrease in uric acid concentration, pro- (IL-1beta, TNF-alpha) and anti-inflammatory cytokine (IL-10) content after treatment in both groups, but more in patients who received carbon enterosorbent with basic therapy. Carbon 201-207 interleukin 10 Homo sapiens 120-125 25854197-6 2015 The combined photothermal effects of the Au nanocrystals and the CDs on/in the carbon shell can not only regulate the release rate of the loaded drug, but also efficiently kill tumor cells under NIR irradiation. Carbon 79-85 NOC2 like nucleolar associated transcriptional repressor Mus musculus 195-198 25581126-0 2015 NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes. Carbon 109-115 NLR family, pyrin domain containing 3 Mus musculus 24-29 32433050-20 2020 Moreover, the HS-induced increase of MDA, lipofuscin, Nox concentrations, and Nox4 expression in DS rats was significantly attenuated by C-ANP4-23 treatment as compared with those with HS diet and vehicle injection (all P < 0.05). Carbon 137-139 NADPH oxidase 4 Rattus norvegicus 78-82 25581126-1 2015 The purpose of this paper is to elucidate the key role of NADPH oxidase in NLRP3 inflammasome activation and generation of pulmonary fibrosis by multi-walled carbon nanotubes (MWCNTs). Carbon 158-164 NLR family, pyrin domain containing 3 Mus musculus 75-80 32968326-5 2020 The sublimation enthalpies of the PFCAs indicate that the contribution to the sublimation enthalpy of the CF2 group in the alkyl chain is comparable to that of the CH2 group in the corresponding non-fluorinated analogues, even though the PFCAs show consistently higher vapor pressures than do the corresponding carbon number alkanoic acids. Carbon 311-317 ATPase H+ transporting accessory protein 1 Homo sapiens 106-109 25946634-2 2015 In this paper, optical sensing performance of tapered multimode fiber tip coated with carbon nanotube (CNT) thin film towards aqueous ethanol with different concentrations is investigated. Carbon 86-92 TOR signaling pathway regulator Homo sapiens 70-73 32073728-0 2020 Effect of phosphorylation in the structural behavior of peptides derived from the intrinsically disordered C-terminal domain of Histone H1.0. Carbon 107-108 H1.0 linker histone Homo sapiens 128-140 26314099-0 2015 [Potential Carbon Fixation Capability of Non-photosynthetic Microbial Community at Different Depth of the South China Sea and Its Response to Different Electron Donors]. Carbon 11-17 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 118-121 32146214-5 2020 Complete Cr6+ reduction via the biological mechanism was observed within 80 days using CM as the carbon source under anaerobic processes with the increased trivalent chromium (Cr3+) concentrations. Carbon 97-103 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 9-12 31968132-12 2020 Both intact and C-terminal FGF23 were significantly elevated in WNT1 mutation-positive subjects (p=0.039 and 0.027, respectively) and normal in PLS3 subjects. Carbon 16-17 fibroblast growth factor 23 Homo sapiens 27-32 26314099-9 2015 The distributions of dissolved oxygen and inorganic carbon concentration with the change of the depth of the sea might be an important reason leading to the difference of NPMC structure and even the difference of PCFC at different depth of the sea. Carbon 52-58 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 109-112 32034861-2 2020 The C-terminus of alpha2AP is crucial for the initial interaction with plasmin(ogen) and the rapid inhibitory mechanism. Carbon 4-5 serpin family F member 2 Homo sapiens 18-26 32034861-3 2020 ~35% of circulating alpha2AP has lost its C-terminus (non-plasminogen binding alpha2AP/NPB-alpha2AP) and thereby its rapid inhibitory capacity. Carbon 42-43 serpin family F member 2 Homo sapiens 20-28 26314099-9 2015 The distributions of dissolved oxygen and inorganic carbon concentration with the change of the depth of the sea might be an important reason leading to the difference of NPMC structure and even the difference of PCFC at different depth of the sea. Carbon 52-58 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 244-247 25327389-1 2015 cis-1,2-Di(1-methyl-2-naphthyl)ethene, c-1,1, undergoes photoisomerization in methylcyclohexane, isopentane and diethyl ether/isopentane/ethanol glasses at 77 K. On 313 nm excitation the fluorescence of c-1,1 is replaced by fluorescence from t-1,1. Carbon 39-40 suppressor of cytokine signaling 1 Homo sapiens 0-5 32537400-3 2020 In this work, coffee residue derived activated ultramicroporous coffee carbon (ACC) material loading with small sulfur molecules (S2-4) as cathode material for RT Na-S batteries is reported. Carbon 71-77 ribosomal protein S24 Homo sapiens 130-134 31965671-2 2020 This is the first synthesis of a rearranged spongian diterpenoid in which the bulky hydrocarbon fragment is joined via a quaternary carbon to the highly hindered concave face of the cis-2,8-dioxabicyclo[3.3.0]octan-3-one moiety. Carbon 89-95 suppressor of cytokine signaling 2 Homo sapiens 182-187 2573826-4 1989 To test the idea that transcriptional regulation of CBP1 could coordinate an increase in cytochrome b mRNA stability with an increase in nuclearly encoded complex III subunit production, we characterized the change in abundance of CBP1 mRNA during derepression on a nonfermentable carbon source. Carbon 281-287 Cbp1p Saccharomyces cerevisiae S288C 52-56 2573826-9 1989 Furthermore, we demonstrated that the levels of the two CBP1 mRNAs were reciprocally regulated by the carbon source in the growth medium. Carbon 102-108 Cbp1p Saccharomyces cerevisiae S288C 56-60 31814539-0 2020 C-terminal of ABCA1 separately regulates cholesterol floppase activity and cholesterol efflux activity. Carbon 0-1 ATP binding cassette subfamily A member 1 Homo sapiens 14-19 25818141-0 2015 Single-walled carbon nanotube based transparent immunosensor for detection of a prostate cancer biomarker osteopontin. Carbon 14-20 secreted phosphoprotein 1 Homo sapiens 106-117 31814539-7 2020 These results suggest that the C-terminal of ABCA1 separately regulates the cholesterol floppase activity and the cholesterol efflux activity. Carbon 31-32 ATP binding cassette subfamily A member 1 Homo sapiens 45-50 32023802-5 2020 The C10 and C11 groups were the predominant carbon groups in all the samples. Carbon 44-50 RNA polymerase III subunit K Homo sapiens 12-15 2605680-5 1989 In this study, the logarithm of the isomerization rate to the delta 2 ester (log k12) correlated with the carbon-13 nuclear magnetic resonance chemical shift difference value at C-3 and C-4 of the delta 3 ester (delta delta (4-3)). Carbon 106-112 complement C3 Homo sapiens 178-181 2676721-5 1989 The HAP4 gene is regulated transcriptionally by a carbon source, suggesting that it encodes a regulatory subunit of the bound complex. Carbon 50-56 transcription factor HAP4 Saccharomyces cerevisiae S288C 4-8 25818141-2 2015 Here, we report a label-free, highly sensitive and transparent immunosensor based on single-walled carbon nanotubes (SWCNTs) for detection of OPN. Carbon 99-105 secreted phosphoprotein 1 Homo sapiens 142-145 25799109-6 2015 Along with As-resistance and -reductase activities, abilities to metabolize a wide range carbon substrates including long chain and polyaromatic hydrocarbons and HCO3, As3+ as electron donor and As5+/Fe3+ as terminal electron acceptor during anaerobic growth were frequently observed within the cultivable bacteria. Carbon 89-95 PDS5 cohesin associated factor B Homo sapiens 168-171 2500148-1 1989 Any one of three homologous genes - STA1, STA2 and STA3 - encoding glucoamylase isozymes I, II and III respectively, allows the Saccharomyces species to utilize starch as a sole carbon source. Carbon 178-184 Wsc2p Saccharomyces cerevisiae S288C 51-55 31889430-1 2020 BACKGROUND: Fibrin polymerization, following fibrinopeptides A and B (FpA, FpB) cleavage, relies on newly exposed alpha- and beta-chains N-termini (GPR, GHR; A-, B-knobs, respectively) engaging pre-existent a and b pockets in other fibrin(ogen) molecules" gamma- and (B)beta-chains C-terminal regions. Carbon 2-3 growth hormone receptor Homo sapiens 153-156 25619729-5 2015 The hydrogen-evolution performance of misfit-layered Bi1.85 Sr2 Co1.85 O7.7-delta , which has an overpotential of 589 mV and a Tafel slope of 51 mV per decade, demonstrates the promising potential of misfit-layered chalcogenides as electrocatalysts instead of classical carbon. Carbon 270-276 transmembrane BAX inhibitor motif containing 6 Homo sapiens 53-56 33488157-0 2020 BET, FTIR, and RAMAN characterizations of activated carbon from waste oil fly ash. Carbon 52-58 bet Drosophila melanogaster 0-3 32031799-5 2020 In comparison to apo-MEF2, an outward disposition of the distal portion of alpha1-helix and movement of its proximal part to beta1 allows synergistic repositioning of the alpha1-alpha2 linker, C-terminal region, and MEF2 domain, resulting in the formation of a hydrophobic groove for DNA binding. Carbon 193-194 immunoglobulin kappa variable 2D-30 Homo sapiens 125-130 2506198-6 1989 In addition to determining production characteristics of PAF by embryos, we also show that the production of CO2 from carbon-1 position of lactate is positively correlated with the ability of embryos to develop during subsequent culture in vitro and therefore could be used as a measure of embryo viability. Carbon 118-124 patchy fur Mus musculus 57-60 25351293-16 2015 Our data suggest that Poly (I:C) decreases in cerebral I/R injury via TLR3 which associates with Fas, thereby preventing the interaction of Fas and FADD, as well as microglial cell caspase-3 and -8 activities. Carbon 30-31 toll-like receptor 3 Mus musculus 70-74 2519722-4 1989 Spin-lattice relaxation times of the various carbon atoms indicated that the overall molecular reorientation time (tau R) of the molecule is 0.02 ns at 30 degrees C. An Arrhenius plot of the data showed that the activation energy (Ea) for molecular tumbling is 13.4 kJ/mol. Carbon 45-51 spindlin 1 Homo sapiens 0-4 2630090-1 1989 New antitumor alkylglycerophospholipids, in which primarily the phosphocholine moiety of the platelet activating factor (PAF) molecule was modified, were synthesized from 1-alkyl-2-substituted glycerols by introducing polar head phosphoryl groups having methylene bridges of various lengths (from 2 to 14 carbons). Carbon 305-312 patchy fur Mus musculus 121-124 32041906-5 2020 The C-terminal region of ORP3 that follows the strictly defined lipid transfer domain, is found to be critical for the proper localization and function of the protein. Carbon 4-5 oxysterol binding protein like 3 Homo sapiens 25-29 31932309-7 2020 In this study, we also discovered that a conserved motif, (V45, V47, L49, P50), within the disordered domain was required for signal transduction to TonB and to the C-terminal domain of ExbD and was the source of motif essentiality.Importance The TonB system is a virulence factor for Gram-negative pathogens. Carbon 165-166 activating signal cointegrator 1 complex subunit 1 Homo sapiens 74-77 25351293-16 2015 Our data suggest that Poly (I:C) decreases in cerebral I/R injury via TLR3 which associates with Fas, thereby preventing the interaction of Fas and FADD, as well as microglial cell caspase-3 and -8 activities. Carbon 30-31 Fas (TNFRSF6)-associated via death domain Mus musculus 148-152 16666686-2 1989 In the presence of 50 micromolar dissolved inorganic carbon and light, protoplasts which had been washed free of external carbonic anhydrase reduced the (13)CO(2) concentration in the medium to close to zero. Carbon 53-59 uncharacterized protein Chlamydomonas reinhardtii 122-140 32164290-2 2020 ATP-citrate lyase (ACL) and cytosolic aconitase (cyt-ACO) are the two citrate-degrading enzymes that decide the carbon flux towards different metabolite biosynthesis pathways. Carbon 112-118 ATP citrate lyase Homo sapiens 0-17 25579916-1 2015 We are introducing mercapto-mesoporous carbon modified carbon paste electrode (mercapto-MP-C-CPE) as a new sensor for trace determination of omeprazole (OM) in biological samples. Carbon 39-45 carboxypeptidase E Homo sapiens 93-96 32164290-2 2020 ATP-citrate lyase (ACL) and cytosolic aconitase (cyt-ACO) are the two citrate-degrading enzymes that decide the carbon flux towards different metabolite biosynthesis pathways. Carbon 112-118 ATP citrate lyase Homo sapiens 19-22 25579916-1 2015 We are introducing mercapto-mesoporous carbon modified carbon paste electrode (mercapto-MP-C-CPE) as a new sensor for trace determination of omeprazole (OM) in biological samples. Carbon 55-61 carboxypeptidase E Homo sapiens 93-96 32328432-3 2020 Here, near-infrared (NIR) chemiluminescent (CL) carbon nanodots (CDs) are fabricated for the first time and their CL quantum yield can reach 9.98 x 10-3 einstein mol-1, which is the highest value ever reported for CDs until now. Carbon 48-54 modifier of LPS-response 1 Mus musculus 162-167 25568326-4 2015 In this paper, we characterize the receptors and the signaling pathways involved in the remarkable apoptosis induced by poly(I:C) transfected by Lipofectamine (in-poly(I:C)) compared with the 12-fold higher free poly(I:C) concentration in PC3 and DU145 cells. Carbon 127-128 proprotein convertase subtilisin/kexin type 1 Homo sapiens 239-242 32049486-3 2020 The PANi is electrodeposited on an electrospun carbon nanofiber textile (denoted PANi@CNF), which not only provides a robust support for PANi to increase its pseudocapacity, but also renders a free-standing architecture for flexible devices. Carbon 47-53 NPHS1 adhesion molecule, nephrin Homo sapiens 86-89 32049486-4 2020 The PANi@CNF composite with a dominant capacitive storage characteristic reveals a high specific capacity of 158.5 mAh gPANi-1 at 1 A g-1 and 118.5 mAh gPANi-1 even at 20 A g-1, which significantly surpasses state-of-the-art porous carbons. Carbon 232-239 NPHS1 adhesion molecule, nephrin Homo sapiens 9-12 2763231-1 1989 Activated carbon is made in Sri Lanka by passing steam through charcoal made from coconut shells. Carbon 10-16 sorcin Homo sapiens 28-31 25568326-4 2015 In this paper, we characterize the receptors and the signaling pathways involved in the remarkable apoptosis induced by poly(I:C) transfected by Lipofectamine (in-poly(I:C)) compared with the 12-fold higher free poly(I:C) concentration in PC3 and DU145 cells. Carbon 170-171 proprotein convertase subtilisin/kexin type 1 Homo sapiens 239-242 25414351-9 2015 GRASP is implemented in GNU C++, and is freely available at http://sourceforge.net/projects/grasp-release. Carbon 28-31 trafficking regulator and scaffold protein tamalin Homo sapiens 0-5 31901812-4 2020 The mixed carbon dots showed a better detection of Hg2+ ions. Carbon 10-16 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 51-54 25554634-5 2015 The psbA gene allows a marker-free selection procedure using as a recipient the Fud7 strain of Chlamydomonas, which grows on media containing acetate as a carbon source, but is unable to grow photoautotrophically due to the lack of an intact psbA gene. Carbon 155-161 photosystem II protein D1 Chlamydomonas reinhardtii 4-8 25488424-7 2015 Interaction analysis of polyinosinic:polycytidylic acid (poly I:C) and dsRNA depicted leucine-rich-repeats (LRR)2-3 and LRR18-19 (in TLR3) and LRRNT-LRR3 and LRR22-24 (in TLR22) as the potential binding sites. Carbon 64-65 toll-like receptor 3 Danio rerio 133-137 25262340-1 2015 In this work, a novel amperometric biosensor of hydrogen peroxide (H2O2) was developed based on the immobilization of myoglobin (Mb) on the surface of the multi-walled carbon nanotube (MWCNT) -Nafion-cysteamine (CA) modified gold electrode (Au) and its electrocatalytic activity was used for the determination of nitrite (NO2(-)). Carbon 168-174 myoglobin Homo sapiens 118-127 25463176-1 2015 In this work, the effects of halloysite nanotubes (HNTs) on the visible-light photocatalytic ability of electrospun carbon doped TiO2/HNT (C-TH) nanofibers have been explored. Carbon 116-122 neurotrimin Homo sapiens 129-137 25502825-1 2015 The potent alpha-glucosidase inhibitor (compound I) was isolated from coffee brews by the activity-based fractionation and identified as a beta-carboline alkaloid norharman (9H-pyrido[ 3.4-b]indole) on the basis of mass spectroscopy and nuclear magnetic resonance spectra ((1)H NMR, (13)C NMR, and COSY). Carbon 287-288 sucrase-isomaltase Homo sapiens 11-28 24972176-1 2015 Sorption of non-ionic organic compounds to soil is usually expressed as the carbon-normalized partition coefficient (KOC), because it is assumed that the main factor that influences the amount sorbed is the organic carbon content of the soil. Carbon 76-82 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 117-120 24972176-1 2015 Sorption of non-ionic organic compounds to soil is usually expressed as the carbon-normalized partition coefficient (KOC), because it is assumed that the main factor that influences the amount sorbed is the organic carbon content of the soil. Carbon 215-221 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 117-120 25190155-10 2015 However, whereas in PC3 cells the response to carbon ion irradiation was enhanced compared with X-irradiation, the effect was the opposite in Caco-2 cells, indicating cell-type-specific responses to the different radiation types. Carbon 46-52 chromobox 8 Homo sapiens 20-23 25394783-1 2015 Human aspartyl-(asparaginyl)-beta-hydroxylase (HAAH) is a type 2 transmembrane protein and an alpha-ketoglutarate-dependent dioxygenase that can stereospecifically catalyze the post-translational hydroxylation reaction of beta-carbon atoms of aspartic acid and asparagine residues present in epidermal growth factor-like domains of certain specific proteins. Carbon 226-233 aspartate beta-hydroxylase Homo sapiens 6-45 25394783-1 2015 Human aspartyl-(asparaginyl)-beta-hydroxylase (HAAH) is a type 2 transmembrane protein and an alpha-ketoglutarate-dependent dioxygenase that can stereospecifically catalyze the post-translational hydroxylation reaction of beta-carbon atoms of aspartic acid and asparagine residues present in epidermal growth factor-like domains of certain specific proteins. Carbon 226-233 aspartate beta-hydroxylase Homo sapiens 47-51 25461681-0 2015 Suppression of c-Myc is involved in multi-walled carbon nanotubes" down-regulation of ATP-binding cassette transporters in human colon adenocarcinoma cells. Carbon 49-55 MYC proto-oncogene, bHLH transcription factor Homo sapiens 15-20 25461681-4 2015 In this study, we found that multiwalled carbon nanotubes (MWCNTs) reduced transport activity and expression of ABC transporters including ABCB1/Pgp and ABCC4/MRP4 in human colon adenocarcinoma Caco-2 cells. Carbon 41-47 phosphoglycolate phosphatase Homo sapiens 145-148 25486052-2 2014 In this work, we showed that mutants of the opportunistic pathogenic yeast Candida lusitaniae which lack the multifunctional enzyme Fox2p, a key enzyme of the ss-oxidation pathway, were still able to grow on fatty acids as the sole carbon source, suggesting that C. lusitaniae harbored an alternative pathway for fatty acid catabolism. Carbon 232-238 bifunctional hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase FOX2 Saccharomyces cerevisiae S288C 132-137 25452167-5 2014 Here, we show that Mdf1p shortens the lag phase of S. cerevisiae by physically interacting with SNF1, the governing factor for nonfermentable carbon source utilization, and thereby confers a selective advantage on yeasts through the rapid consumption of glucose in the early generational stage in rich medium. Carbon 142-148 Fyv5p Saccharomyces cerevisiae S288C 19-24 25356936-6 2014 In the CT/PDI model, the pi pi* excitation in azobenzenes is manifested as drastically increasing atomic induced dipole moments in the azo group as well as in the adjacent carbon atoms, whereas the shifts in the excitation energies are due to charge-transfer effects. Carbon 174-180 peptidyl arginine deiminase 1 Homo sapiens 10-13 25293654-0 2014 NiP2 nanosheet arrays supported on carbon cloth: an efficient 3D hydrogen evolution cathode in both acidic and alkaline solutions. Carbon 35-41 BCL2 interacting protein 2 Homo sapiens 0-4 25293654-2 2014 In this communication, we develop a two-step strategy for constructing NiP2 nanosheet arrays on carbon cloth (NiP2 NS/CC). Carbon 96-102 BCL2 interacting protein 2 Homo sapiens 71-75 25293654-2 2014 In this communication, we develop a two-step strategy for constructing NiP2 nanosheet arrays on carbon cloth (NiP2 NS/CC). Carbon 96-102 BCL2 interacting protein 2 Homo sapiens 110-114 25365506-3 2014 In this work, we show that JEN1 mRNA accumulates in a dhh1 mutant, when formic acid was used as sole carbon source. Carbon 101-107 Jen1p Saccharomyces cerevisiae S288C 27-31 25254947-4 2014 The behavior of the surfactant adsorption under different concentrations of divalent cations was well-described by the use of a new modified Langmuir model: (dGamma/dt)ads = k(ads)c(Gamma - Gamma) - k(cmc)(c - c(cmc))(n)GammaH(c - c(cmc)). Carbon 25-26 Adaptor Protein complex 1, gamma subunit Drosophila melanogaster 158-164 24271883-5 1989 The large change int 1/2 with temperature and with number of carbon atoms is a consequence of the thermodynamic relationships and the temperature range of pheromone usage. Carbon 61-67 integrator complex subunit 12 Homo sapiens 17-24 25254947-4 2014 The behavior of the surfactant adsorption under different concentrations of divalent cations was well-described by the use of a new modified Langmuir model: (dGamma/dt)ads = k(ads)c(Gamma - Gamma) - k(cmc)(c - c(cmc))(n)GammaH(c - c(cmc)). Carbon 25-26 Adaptor Protein complex 1, gamma subunit Drosophila melanogaster 159-164 25254947-4 2014 The behavior of the surfactant adsorption under different concentrations of divalent cations was well-described by the use of a new modified Langmuir model: (dGamma/dt)ads = k(ads)c(Gamma - Gamma) - k(cmc)(c - c(cmc))(n)GammaH(c - c(cmc)). Carbon 25-26 Adaptor Protein complex 1, gamma subunit Drosophila melanogaster 182-187 2537040-2 1989 To test whether these receptors (C-ANF receptors) function as clearance receptors for circulating ANF-(1-28), we determined the effects of C-ANF-(4-23) [des[Gln18Ser19Gly20Leu21Gly22]rANF-(3-23)-NH2], a specific ligand of C-ANF receptors, on the pharmacokinetics and hydrolysis of 125I-labeled ANF-(1-28) in anesthetized rats. Carbon 33-34 natriuretic peptide A Rattus norvegicus 98-101 2537040-2 1989 To test whether these receptors (C-ANF receptors) function as clearance receptors for circulating ANF-(1-28), we determined the effects of C-ANF-(4-23) [des[Gln18Ser19Gly20Leu21Gly22]rANF-(3-23)-NH2], a specific ligand of C-ANF receptors, on the pharmacokinetics and hydrolysis of 125I-labeled ANF-(1-28) in anesthetized rats. Carbon 33-34 natriuretic peptide A Rattus norvegicus 98-101 25254947-4 2014 The behavior of the surfactant adsorption under different concentrations of divalent cations was well-described by the use of a new modified Langmuir model: (dGamma/dt)ads = k(ads)c(Gamma - Gamma) - k(cmc)(c - c(cmc))(n)GammaH(c - c(cmc)). Carbon 58-59 Adaptor Protein complex 1, gamma subunit Drosophila melanogaster 158-164 2537040-2 1989 To test whether these receptors (C-ANF receptors) function as clearance receptors for circulating ANF-(1-28), we determined the effects of C-ANF-(4-23) [des[Gln18Ser19Gly20Leu21Gly22]rANF-(3-23)-NH2], a specific ligand of C-ANF receptors, on the pharmacokinetics and hydrolysis of 125I-labeled ANF-(1-28) in anesthetized rats. Carbon 33-34 natriuretic peptide A Rattus norvegicus 98-101 2537040-2 1989 To test whether these receptors (C-ANF receptors) function as clearance receptors for circulating ANF-(1-28), we determined the effects of C-ANF-(4-23) [des[Gln18Ser19Gly20Leu21Gly22]rANF-(3-23)-NH2], a specific ligand of C-ANF receptors, on the pharmacokinetics and hydrolysis of 125I-labeled ANF-(1-28) in anesthetized rats. Carbon 33-34 natriuretic peptide A Rattus norvegicus 98-101 25254947-4 2014 The behavior of the surfactant adsorption under different concentrations of divalent cations was well-described by the use of a new modified Langmuir model: (dGamma/dt)ads = k(ads)c(Gamma - Gamma) - k(cmc)(c - c(cmc))(n)GammaH(c - c(cmc)). Carbon 58-59 Adaptor Protein complex 1, gamma subunit Drosophila melanogaster 159-164 25254947-4 2014 The behavior of the surfactant adsorption under different concentrations of divalent cations was well-described by the use of a new modified Langmuir model: (dGamma/dt)ads = k(ads)c(Gamma - Gamma) - k(cmc)(c - c(cmc))(n)GammaH(c - c(cmc)). Carbon 58-59 Adaptor Protein complex 1, gamma subunit Drosophila melanogaster 158-164 25254947-4 2014 The behavior of the surfactant adsorption under different concentrations of divalent cations was well-described by the use of a new modified Langmuir model: (dGamma/dt)ads = k(ads)c(Gamma - Gamma) - k(cmc)(c - c(cmc))(n)GammaH(c - c(cmc)). Carbon 58-59 Adaptor Protein complex 1, gamma subunit Drosophila melanogaster 159-164 16347851-7 1989 The following chemicals were completely degraded (>/=80% ThGP) at a concentration of 50 mg of carbon per liter: phenol, 2-aminophenol, 4-cresol, catechol, sodium benzoate, 4-aminobenzoic acid, 3-chlorobenzoic acid, phthalic acid, ethylene glycol, diethylene glycol, triethylene glycol, sodium stearate, and quinoline. Carbon 97-103 uromodulin Homo sapiens 60-64 25173632-0 2014 Heterologous expression of AtPAP2 in transgenic potato influences carbon metabolism and tuber development. Carbon 66-72 Purple acid phosphatases superfamily protein Arabidopsis thaliana 27-33 2783613-3 1989 The steric bulk of the nitrogen and methylene bridges in addition to ring strain present in the proposed carbon-centered radical intermediates derived from these types of tricyclic structures may contribute to their relatively poor MAO-B substrate properties. Carbon 105-111 monoamine oxidase B Rattus norvegicus 232-237 25128671-3 2014 In particular, derivatives possessing a six or seven carbon chain linker between 2-benzothiazolone and arylpiperazine had Ki values in the subnanomolar range for the 5-HT1A receptor and in the low nanomolar range for the 5-HT7 receptor, indicating that they may be interesting dual ligands. Carbon 53-59 5-hydroxytryptamine receptor 1A Homo sapiens 166-181 3264158-1 1988 C1-tetrahydrofolate synthase (C1-THF synthase) is a trifunctional enzyme which catalyzes the interconversion of one-carbon units attached to the coenzyme THF. Carbon 116-122 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Rattus norvegicus 0-28 3264158-1 1988 C1-tetrahydrofolate synthase (C1-THF synthase) is a trifunctional enzyme which catalyzes the interconversion of one-carbon units attached to the coenzyme THF. Carbon 116-122 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Rattus norvegicus 30-45 29512971-0 2014 CHP systems to save money and cut carbon. Carbon 34-40 calcineurin like EF-hand protein 1 Homo sapiens 0-3 3062377-6 1988 When the GAL11 locus was disrupted by insertion of the URA3 gene, the resulting yeast cells (gal11::URA3) exhibited phenotypes almost identical to those of the gal11 strains, with respect to both galactose utilization and growth on nonfermentable carbon sources. Carbon 247-253 Gal11p Saccharomyces cerevisiae S288C 9-14 3062377-6 1988 When the GAL11 locus was disrupted by insertion of the URA3 gene, the resulting yeast cells (gal11::URA3) exhibited phenotypes almost identical to those of the gal11 strains, with respect to both galactose utilization and growth on nonfermentable carbon sources. Carbon 247-253 Gal11p Saccharomyces cerevisiae S288C 93-98 3379303-9 1988 When macrophages were exposed to poly [I:C] in the presence of an anti-mouse IFN-alpha/beta antiserum, the changes in the synthesis of factor B, C3, and beta-glucuronidase were partially inhibited. Carbon 41-42 interferon alpha Mus musculus 77-86 3379303-9 1988 When macrophages were exposed to poly [I:C] in the presence of an anti-mouse IFN-alpha/beta antiserum, the changes in the synthesis of factor B, C3, and beta-glucuronidase were partially inhibited. Carbon 41-42 complement factor B Mus musculus 135-143 25100852-7 2014 The PCP domain was shown to have deubiquitinase activity for both RIG-I and TBK-1, whose ubiquitination is a key step in their activation in poly(I C)-induced IFN induction. Carbon 5-6 TANK binding kinase 1 Homo sapiens 76-81 24605822-6 2014 Hydrogen bonding of the side-chain hydroxyl group with a backbone carbonyl oxygen aligns the singly occupied pi orbital on the beta-carbon and the N-Calpha bond, leading to low-barrier beta-cleavage of the N-Calpha bond. Carbon 66-72 CEA cell adhesion molecule 6 Homo sapiens 147-155 3166990-0 1988 13C NMR studies of methylene and methine carbons of substrate bound to a 280,000-dalton protein, porphobilinogen synthase. Carbon 41-48 aminolevulinate dehydratase Homo sapiens 97-121 24605822-6 2014 Hydrogen bonding of the side-chain hydroxyl group with a backbone carbonyl oxygen aligns the singly occupied pi orbital on the beta-carbon and the N-Calpha bond, leading to low-barrier beta-cleavage of the N-Calpha bond. Carbon 66-72 CEA cell adhesion molecule 6 Homo sapiens 206-214 25192230-3 2014 RESULTS: An interquartile range increase (0.11 mug/m) in annual mean residential black carbon was associated with 12% (95% confidence interval: 3%, 22%) higher leptin levels. Carbon 87-93 leptin Homo sapiens 160-166 3375943-3 1988 A card test utilising the VDR carbon antigen (Wellcome) was used to screen cord blood samples for reagin reactivity. Carbon 30-36 vitamin D receptor Homo sapiens 26-29 24913862-0 2014 A new Methimazole sensor based on nanocomposite of CdS NPs-RGO/IL-carbon paste electrode using differential FFT continuous linear sweep voltammetry. Carbon 66-72 CDP-diacylglycerol synthase 1 Homo sapiens 51-54 2482759-9 1988 On the other hand, with the hybrid strategy, which involved the consideration of realistic energy terms in the early stages of the calculations, it was possible to calculate low-energy conformations of BPTI with rms deviations from the X-ray structure of 1.06 to 1.50 A for the alpha-carbons. Carbon 284-291 spleen trypsin inhibitor I Bos taurus 202-206 3337720-3 1988 A non-cyclic pathway is suggested (reaction 2) for the direct biosynthesis of sucrose from the 3-PGA obtained from C-3, C-4 and C-5 of the six-carbon carboxylation adduct. Carbon 143-149 complement C3 Homo sapiens 115-118 3542971-12 1987 Complete aerobic utilization of carbons 4 through 6 of L-fucose depends not only on an adequate activity of aldehyde dehydrogenase to trap L-lactaldehyde as its anionic acid but also on the lack of L-1,2-propanediol oxidoreductase activity, which converts L-lactaldehyde to a readily excreted alcohol. Carbon 32-39 oxidoreductase Escherichia coli 216-230 25037205-4 2014 We found novel compound heterozygous mutations, c.944G>A [p.C315Y] and c.856C>T [p.Q286X], in the TSFM gene encoding mitochondrial EFTs. Carbon 15-16 Ts translation elongation factor, mitochondrial Homo sapiens 104-108 3309140-1 1987 The cdc30 mutation in the yeast Saccharomyces cerevisiae causes cell cycle arrest late in nuclear division when cells are shifted from the permissive temperature of 25 degrees C to the restrictive temperature of 36.5 degrees C. Cell cycle arrest at 36.5 degrees C is dependent upon the carbon source used: a shift-up in glucose containing media results in cell cycle blockade, whereas a shift-up in ethanol, fructose, glycerol, glycerol plus ethanol, or mannose does not. Carbon 286-292 glucose-6-phosphate isomerase Saccharomyces cerevisiae S288C 4-9 3024570-1 1986 Heme-catalyzed decomposition of unsaturated hydroperoxy fatty acids has been proposed to proceed via carbon-centered free radicals (delocalized at positions C11, C12, and C13 for 15-hydroperoxy-eicosatetraenoic acid (15-HPETE). Carbon 101-107 RNA polymerase III subunit K Homo sapiens 157-160 31761904-8 2020 Based on the localization of missense variants and in-frame deletions, three clinical subgroups arise that differ significantly regarding main clinical features and are directly related to the affected region of the NBAS protein: beta-propeller (combined phenotype), Sec39 (infantile liver failure syndrome type 2/ILFS2), and C-terminal (short stature, optic atrophy, and Pelger-Huet anomaly/SOPH). Carbon 326-327 NBAS subunit of NRZ tethering complex Homo sapiens 216-220 25010511-2 2014 The addition of hydrogen peroxide (30% aq) as a co-oxidant in the system is crucial for the dehydrogenative aminohalogenation under molecular oxygen (1 atm), and in such a case, the C-N bond coupling/electrophilic bromination reaction cascade is proposed. Carbon 182-183 ATM serine/threonine kinase Homo sapiens 152-155 31843259-10 2020 The concomitant decrease of STAT1 and STAT2 and the increase of STAT6 genes abundance at 41 C suggest, at transcriptional factors level, a polarization of monocytes from a classical activated M1 to a non-classically activated M2 monocytes. Carbon 93-94 signal transducer and activator of transcription 6 Bos taurus 64-69 3024570-1 1986 Heme-catalyzed decomposition of unsaturated hydroperoxy fatty acids has been proposed to proceed via carbon-centered free radicals (delocalized at positions C11, C12, and C13 for 15-hydroperoxy-eicosatetraenoic acid (15-HPETE). Carbon 101-107 homeobox C13 Homo sapiens 171-174 3024570-6 1986 We proposed that these radical adducts are derived from C11 and C13 carbon-centered free radicals generated in the decomposition of 15-HPETE. Carbon 68-74 homeobox C13 Homo sapiens 64-67 3020369-10 1986 Also the pgi1 delta strains did not grow in glucose as sole carbon source. Carbon 60-66 glucose-6-phosphate isomerase Saccharomyces cerevisiae S288C 9-13 31796534-5 2020 PPARdelta-YAP1 interaction occurred via the C-terminal domain of YAP1, and both TEAD and PPARE binding sites were required for SOX9 induction. Carbon 44-45 peroxisome proliferator activated receptor delta Homo sapiens 0-9 24940842-3 2014 Herein, uniform carbon-encapsulated Ge and GeOx nanowires were synthesized by a one-step controlled pyrolysis of organic-inorganic hybrid GeOx/ethylenediamine (GeOx/EDA) nanowires in H2/Ar and Ar atmospheres, respectively. Carbon 16-22 H2A clustered histone 19 Homo sapiens 183-188 31945260-7 2020 From multivariate analyses adjusted for age, sex, and BMI, several phospholipids containing long chain PUFA with 20-22 carbons (phosphatidylcholines, phosphatidylethanolamines, phosphatidylinositols, and a phosphatidylserine), were positively associated with ferritin and the ferritin/adiponectin ratio. Carbon 119-126 pumilio RNA binding family member 3 Homo sapiens 103-107 2992516-6 1985 The results indicate a role for the catecholamines and angiotensin II in the regulation of liver fat metabolism and emphasize the potential importance of changes in activity of PEPCK as determinants of hepatic carbon flux. Carbon 210-216 phosphoenolpyruvate carboxykinase 1 Rattus norvegicus 177-182 3157191-5 1985 When sn-1,2-diacylglycerols containing fatty acids 3-10 carbons in length were added to 2C5 cells, those diacylglycerols containing fatty acids 5-10 carbons in length caused ODCase induction and reduction in EGF binding. Carbon 56-63 ornithine decarboxylase, structural 1 Mus musculus 174-180 31932304-6 2020 The results of these analyses indicated that Opi3 (as well as PEMT) has an N-out C-in topology and contains four transmembrane domains, with the fourth forming a re-entrant loop. Carbon 81-82 bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase Saccharomyces cerevisiae S288C 45-49 31932304-7 2020 On the basis of the sequence conservation between the C-terminal half of Opi3 and isoprenyl cysteine carboxyl methyltransferases (ICMTs) with a solved crystal structure, we identified amino acids critical for Opi3 activity by site-directed mutagenesis. Carbon 54-55 bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase Saccharomyces cerevisiae S288C 73-77 31932304-7 2020 On the basis of the sequence conservation between the C-terminal half of Opi3 and isoprenyl cysteine carboxyl methyltransferases (ICMTs) with a solved crystal structure, we identified amino acids critical for Opi3 activity by site-directed mutagenesis. Carbon 54-55 bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase Saccharomyces cerevisiae S288C 210-214 31932304-8 2020 Modeling of the structure of the C-terminal part of Opi3 was consistent with the topology obtained by SCAM, and revealed that the active site faces the cytosol. Carbon 33-34 bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase Saccharomyces cerevisiae S288C 52-56 24939862-8 2014 Two-electron reduction of 3 with C8K affords, after elimination of one IMe4 group, the thermolabile, carbene-stabilized 1-silacyclopentadien-1-ylidene Si{C4(NEt2)4}(IMe4) (4), which was characterized by elemental analysis and (1)H, (13)C{(1)H}, and (29)Si{(1)H} NMR spectroscopies. Carbon 33-34 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Homo sapiens 71-75 31792058-7 2020 Remarkably, a chimeric BET protein comprising the N-terminal half of the structurally similar short BRD4 isoform (BRD4S) and the C-terminal half of BRD2 functioned similarly to intact BRD2. Carbon 129-130 bromodomain containing 2 Homo sapiens 148-152 3157191-5 1985 When sn-1,2-diacylglycerols containing fatty acids 3-10 carbons in length were added to 2C5 cells, those diacylglycerols containing fatty acids 5-10 carbons in length caused ODCase induction and reduction in EGF binding. Carbon 149-156 ornithine decarboxylase, structural 1 Mus musculus 174-180 24939862-8 2014 Two-electron reduction of 3 with C8K affords, after elimination of one IMe4 group, the thermolabile, carbene-stabilized 1-silacyclopentadien-1-ylidene Si{C4(NEt2)4}(IMe4) (4), which was characterized by elemental analysis and (1)H, (13)C{(1)H}, and (29)Si{(1)H} NMR spectroscopies. Carbon 33-34 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit Homo sapiens 165-169 31801860-4 2020 We here identify the cellular Ubiquitin-specific-processing protease 7 (Usp7) as a new interaction partner of the MCPyV LT.Using GST pulldown experiments, we show that MCPyV LT directly binds to Usp7, and that N- as well as the C-terminal regions of LT bind to the TRAF (tumor necrosis factor receptor-associated) domain of Usp7. Carbon 115-116 ubiquitin specific peptidase 7 Homo sapiens 72-76 24792328-9 2014 In conclusion, short-term inhalation exposure to pure carbon nanoparticles can trigger mild p47(phox) dependent oxidative stress responses in the lungs of mice whereas in their brains at the same exposure levels signs of oxidative stress and inflammation remain absent. Carbon 54-60 milk fat globule EGF and factor V/VIII domain containing Mus musculus 92-95 31801860-4 2020 We here identify the cellular Ubiquitin-specific-processing protease 7 (Usp7) as a new interaction partner of the MCPyV LT.Using GST pulldown experiments, we show that MCPyV LT directly binds to Usp7, and that N- as well as the C-terminal regions of LT bind to the TRAF (tumor necrosis factor receptor-associated) domain of Usp7. Carbon 115-116 ubiquitin specific peptidase 7 Homo sapiens 195-199 31801860-4 2020 We here identify the cellular Ubiquitin-specific-processing protease 7 (Usp7) as a new interaction partner of the MCPyV LT.Using GST pulldown experiments, we show that MCPyV LT directly binds to Usp7, and that N- as well as the C-terminal regions of LT bind to the TRAF (tumor necrosis factor receptor-associated) domain of Usp7. Carbon 115-116 ubiquitin specific peptidase 7 Homo sapiens 195-199 31866294-2 2020 Several substrates, including GMPS, UHRF1, and ICP0, were shown to bear a specific KxxxK motif that interacts within the C-terminal region of USP7. Carbon 48-49 ubiquitin specific peptidase 7 Homo sapiens 142-146 3971900-10 1985 Perfusions of fatty acids of four or more carbons and alcohols of two or more carbons resulted in a 2- to 4-fold increase of both NT and NT(1-8) levels in plasma. Carbon 78-85 neurotensin Rattus norvegicus 130-132 3971900-10 1985 Perfusions of fatty acids of four or more carbons and alcohols of two or more carbons resulted in a 2- to 4-fold increase of both NT and NT(1-8) levels in plasma. Carbon 78-85 neurotensin Rattus norvegicus 137-139 3971900-11 1985 It is particularly interesting that perfusion with ethanol (2-carbons) causes an elevation in plasma NT, because perfusion with acetic acid (2-carbons) does not increase NTLI. Carbon 62-69 neurotensin Rattus norvegicus 101-103 24884962-2 2014 The reaction of phenyl with 1,2-butadiene is initiated by adding the phenyl radical with its radical center to the pi electron density at the C1/C3 carbon atom of 1,2-butadiene. Carbon 148-154 heterogeneous nuclear ribonucleoprotein C Homo sapiens 142-147 6618761-5 1983 Comparison of carbon-13 nuclear magnetic resonance spectra obtained under identical conditions for the coacervate states of the PPP of elastin and the D-Ala5 analog shows the effect of replacing the Gly5 residue by a D-Ala5 residue to be one of greatly restricting mobility of the polypeptide chain. Carbon 14-20 elastin Homo sapiens 135-142 32054026-3 2020 Carbon nanomaterials are prepared in Ar, He, Ar-H2, and Ar-N2 via propane decomposition, and the product characterization is performed by transmission electron microscopy (TEM), Raman spectroscopy, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and the Brunauer-Emmett-Teller (BET) method. Carbon 0-6 ADP-ribosylhydrolase like 1 Homo sapiens 45-50 31793743-5 2020 Combined in vivo intravital microscopy and lentiviral rescue experiments with in vitro cell culture demonstrated that MT1-MMP activity in endothelial cells is required for vasodilation and IA, as well as for nitric oxide production via binding of the C-terminal fragment of MT1-MMP substrate thrombospondin-1 (TSP1) to CD47/alphavbeta3 integrin. Carbon 0-1 matrix metallopeptidase 14 (membrane-inserted) Mus musculus 118-125 6341814-2 1983 The ADR1 gene is required for synthesis of the glucose-repressible alcohol dehydrogenase (ADHII) when S. cerevisiae cells are grown on a nonfermentable carbon source, whereas the ADR1-5c allele allows ADHII synthesis even during glucose repression. Carbon 152-158 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 4-8 24884962-3 2014 Later, the initial collision complexes isomerize via phenyl group migration from the C1/C3 carbon atoms to the C2 carbon atom of the allene moiety of 1,2-butadiene. Carbon 91-97 heterogeneous nuclear ribonucleoprotein C Homo sapiens 85-90 6279450-6 1982 The glucose moieties of glucose 1-phosphate, glucose 6-phosphate and glucose 1,6-bisphosphate were degraded and showed that epididymal fat pad enzymes relocate 14C from [2-14C]glucose into C-1, C-2, and C-3 of each hexose-phosphate. Carbon 162-163 complement C3 Rattus norvegicus 203-206 7133987-3 1982 Calcium effects within the cell are mostly mediated through binding of the ion to low molecular weight proteins that form an evolutionary family including parvalbumin, calmodulin, troponin C, the alkali and regulatory light chains of myosin, the S-100 protein and the vitamin D-dependent intestinal calcium-binding protein. Carbon 0-1 parvalbumin Homo sapiens 155-166 32029834-2 2020 To this purpose, polymerization of melamine and terephthalaldehyde (MT) was performed in the presence of amine-functionalized carbon coated Hal (Hal@Glu-2N) that was prepared from hydrothermal treatment of Hal and glucose. Carbon 126-132 histidine ammonia-lyase Homo sapiens 140-143 32029834-2 2020 To this purpose, polymerization of melamine and terephthalaldehyde (MT) was performed in the presence of amine-functionalized carbon coated Hal (Hal@Glu-2N) that was prepared from hydrothermal treatment of Hal and glucose. Carbon 126-132 histidine ammonia-lyase Homo sapiens 145-148 32029834-2 2020 To this purpose, polymerization of melamine and terephthalaldehyde (MT) was performed in the presence of amine-functionalized carbon coated Hal (Hal@Glu-2N) that was prepared from hydrothermal treatment of Hal and glucose. Carbon 126-132 histidine ammonia-lyase Homo sapiens 145-148 24884962-3 2014 Later, the initial collision complexes isomerize via phenyl group migration from the C1/C3 carbon atoms to the C2 carbon atom of the allene moiety of 1,2-butadiene. Carbon 114-120 heterogeneous nuclear ribonucleoprotein C Homo sapiens 85-90 24873414-3 2014 In this work, binary heterogeneous nanocomplexes (termed as C-dots-AuNC) constructed from gold clusters and carbon dots were reported. Carbon 108-114 steroid sulfatase Homo sapiens 57-61 31836385-5 2020 The uricase/carboxymethylcellulose dispersed carbon nanotube/gold thin film biosensor shows the best sensing performance compared to that with sodium cholate surfactant in terms of higher current and lower detection potential. Carbon 45-51 urate oxidase (pseudogene) Homo sapiens 4-11 31502903-0 2020 N6-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon black particles in rats. Carbon 158-164 mechanistic target of rapamycin kinase Rattus norvegicus 80-84 31928655-0 2020 The C-terminal extension of Arabidopsis Uev1A/B with putative prenylation site plays critical roles in protein interaction, subcellular distribution and membrane association. Carbon 4-5 MMS ZWEI homologue 1 Arabidopsis thaliana 40-45 6277620-4 1981 Quantitative estimation of O-2 radicals, with either succinylated ferricytochrome c or epinephrine used as O-2 scavengers, revealed that only about 6% of the total electron flux channelled via putidamonooxin to dioxygen led to the monovalent reduction on dioxygen. Carbon 35-36 immunoglobulin kappa variable 1D-39 Homo sapiens 27-30 31928655-4 2020 The Arabidopsis thaliana genome contains four UEV1 genes that can be classified into two subfamilies (UEV1A/B and UEV1C/D), in which Uev1A/B have a C-terminal extension. Carbon 118-119 MMS ZWEI homologue 1 Arabidopsis thaliana 133-140 24877755-2 2014 The reaction proceeds under catalytic RuH2(CO)(PPh3)3 conditions driven by the activation of the unreactive C-N bond by amide directing group (DG)-Ru catalyst chelation. Carbon 43-44 protein phosphatase 4 catalytic subunit Homo sapiens 47-51 31928655-4 2020 The Arabidopsis thaliana genome contains four UEV1 genes that can be classified into two subfamilies (UEV1A/B and UEV1C/D), in which Uev1A/B have a C-terminal extension. Carbon 148-149 MMS ZWEI homologue 1 Arabidopsis thaliana 102-107 31928655-4 2020 The Arabidopsis thaliana genome contains four UEV1 genes that can be classified into two subfamilies (UEV1A/B and UEV1C/D), in which Uev1A/B have a C-terminal extension. Carbon 148-149 MMS ZWEI homologue 1 Arabidopsis thaliana 133-140 31928655-6 2020 Interestingly, all C-terminal tails in the Uev1A/B subfamily contain a putative prenylation motif, CaaX. Carbon 19-20 MMS ZWEI homologue 1 Arabidopsis thaliana 43-48 31928655-9 2020 These results collectively imply that prenylation of AtUev1A/B plays a critical role in its functional differentiation from AtUev1C/D. Carbon 130-131 MMS ZWEI homologue 1 Arabidopsis thaliana 53-62 31816744-2 2020 GOx was immobilized on a novel sensing platform consisting of poly(brilliant green) films formed by potential cycling electropolymerization in sulfuric acid doped ethaline deep eutectic solvent on multiwalled carbon nanotube modified glassy carbon electrodes. Carbon 209-215 hydroxyacid oxidase 1 Homo sapiens 0-3 31816744-2 2020 GOx was immobilized on a novel sensing platform consisting of poly(brilliant green) films formed by potential cycling electropolymerization in sulfuric acid doped ethaline deep eutectic solvent on multiwalled carbon nanotube modified glassy carbon electrodes. Carbon 241-247 hydroxyacid oxidase 1 Homo sapiens 0-3 6790577-9 1981 However, the H-protein from the patient could stimulate the P-protein catalyzed exchange of the carboxyl carbon of glycine with 14CO2, although the specific activity of the purified H-protein from the patient was only 4% of that of control human H-protein. Carbon 105-111 myosin binding protein H Homo sapiens 13-22 16661286-10 1980 The apparent lack of cooperation between the mesophyll and bundle sheath cells may have been due to inadequate levels of NADP-malic enzyme required for shuttling carbon as CO(2) from the PEP carboxylase products to the Calvin cycle. Carbon 162-168 phosphoenolpyruvate carboxylase 1 Zea mays 187-202 24916201-3 2014 The nanoparticles located at the edges or attached to the steps on the FLG sheets create trenches and tunnels with orientations, lengths and morphologies defined by the crystallography and the topography of the carbon substrate. Carbon 211-217 filaggrin Homo sapiens 71-74 7194068-4 1980 on the C-2 carbon atom of the heterocycles. Carbon 11-17 complement C2 Gallus gallus 7-10 31723002-6 2020 Conversely, GSK3beta phosphorylated serine and threonine sites in the C-terminal domain of NDRG1, and limited the protein stability of NDRG1. Carbon 0-1 N-myc downstream regulated 1 Homo sapiens 91-96 31723002-6 2020 Conversely, GSK3beta phosphorylated serine and threonine sites in the C-terminal domain of NDRG1, and limited the protein stability of NDRG1. Carbon 0-1 N-myc downstream regulated 1 Homo sapiens 135-140 24892923-4 2014 Infrared, Raman and (13)C nuclear magnetic resonance signatures substantiate carbon dioxide fixation by polymerization in the carbon channels to form poly(CO2) under much lower pressures than previously required. Carbon 77-83 complement C2 Homo sapiens 155-158 31941332-0 2020 Sn-modification of Pt7/alumina model catalysts: Suppression of carbon deposition and enhanced thermal stability. Carbon 63-69 zinc finger protein 79 Homo sapiens 19-22 31889000-3 2020 Here we report that Ndel1"s C-terminal coiled-coil region (CT-CC) binds to giant neuron-specific insertion regions present in both AnkG and AnkB with 2:1 stoichiometry. Carbon 28-29 nudE neurodevelopment protein 1 like 1 Homo sapiens 20-25 6987054-6 1980 Moreover, FCCP also inhibited ppGpp degradation in a ATPase-deficient strain growing on glucose as carbon source while, as expected, it did not change the level of ATP. Carbon 99-105 ATPase Escherichia coli 53-59 7408842-5 1980 The measured values of the vicinal coupling constants between H-1" and the C-8 and C-4 carbons were employed to evaluate approximately the glycosidic angles chi of the nucleosides in the conformations syn and anti. Carbon 87-94 synemin Homo sapiens 201-204 24769391-1 2014 A poly-beryllon II film modified carbon paste electrode (PBL-II/CPE) has been constructed by electropolymerization method. Carbon 33-39 carboxypeptidase E Homo sapiens 57-67 444472-3 1979 At high substrate/enzyme ratios, the spin-spin relaxation rates of C(1)-C(3) are faster than for the other carbons and are in the order C(1) greater than C(2) greater than C(3). Carbon 67-68 spindlin 1 Homo sapiens 37-41 444472-3 1979 At high substrate/enzyme ratios, the spin-spin relaxation rates of C(1)-C(3) are faster than for the other carbons and are in the order C(1) greater than C(2) greater than C(3). Carbon 67-68 spindlin 1 Homo sapiens 42-46 444472-3 1979 At high substrate/enzyme ratios, the spin-spin relaxation rates of C(1)-C(3) are faster than for the other carbons and are in the order C(1) greater than C(2) greater than C(3). Carbon 107-114 spindlin 1 Homo sapiens 37-41 444472-3 1979 At high substrate/enzyme ratios, the spin-spin relaxation rates of C(1)-C(3) are faster than for the other carbons and are in the order C(1) greater than C(2) greater than C(3). Carbon 107-114 spindlin 1 Homo sapiens 42-46 444472-3 1979 At high substrate/enzyme ratios, the spin-spin relaxation rates of C(1)-C(3) are faster than for the other carbons and are in the order C(1) greater than C(2) greater than C(3). Carbon 72-73 spindlin 1 Homo sapiens 37-41 32055286-6 2020 Our analysis of the interaction network of sigma1R indicates that a set of residues near E102 is critical for the integrity of C-terminal ligand-binding domain. Carbon 127-128 sigma non-opioid intracellular receptor 1 Homo sapiens 43-50 31912282-3 2020 When placed on a glassy carbon electrode, the sensor exhibits attractive figures of merit for sensing glucose in 0.1 M NaOH solution including (a) a wide linear range (0.005-7 mM), (b) a low determination limit (0.36 muM), (c) high sensitivity (6115 muA muM-1 cm-2), (d) a relatively low working potential (0.50 V vs. Ag/AgCl), and (e) good selectivity, reproducibility, and stability. Carbon 24-30 PWWP domain containing 3A, DNA repair factor Homo sapiens 254-259 24980763-2 2014 The aim of the study was to evaluate the myeloprotective possibilities of carbon enterosorbents in the case of usage of alkilating drug melphalan (L-PAM). Carbon 74-80 peptidylglycine alpha-amidating monooxygenase Rattus norvegicus 149-152 31833502-10 2020 Lastly, the C13 potential is employed to model, for the first time, the tensile and the compressive behaviors of the hybrid system composed of carbon nanotubes infilled with carbyne chains. Carbon 143-149 homeobox C13 Homo sapiens 12-15 444472-3 1979 At high substrate/enzyme ratios, the spin-spin relaxation rates of C(1)-C(3) are faster than for the other carbons and are in the order C(1) greater than C(2) greater than C(3). Carbon 72-73 spindlin 1 Homo sapiens 42-46 444472-3 1979 At high substrate/enzyme ratios, the spin-spin relaxation rates of C(1)-C(3) are faster than for the other carbons and are in the order C(1) greater than C(2) greater than C(3). Carbon 72-73 spindlin 1 Homo sapiens 37-41 444472-3 1979 At high substrate/enzyme ratios, the spin-spin relaxation rates of C(1)-C(3) are faster than for the other carbons and are in the order C(1) greater than C(2) greater than C(3). Carbon 72-73 spindlin 1 Homo sapiens 42-46 444472-6 1979 Spin-spin and spin-lattice relaxation rates were measured for odd-carbon 13C-enriched 1-dodecanal in the presence of luciferase. Carbon 66-72 spindlin 1 Homo sapiens 0-4 31897753-1 2020 Multiwalled carbon nanotubes coated with cobalt(II) sulfide nanoparticles were prepared and used for immobilization of glucose oxidase (GOx) to obtain an electrochemical glucose biosensor. Carbon 12-18 hydroxyacid oxidase 1 Homo sapiens 136-139 24731807-8 2014 Mice were vaccinated by intratracheal route with HAC1/SiO2 or HAC1/c-di-GMP (single-adjuvanted vaccine) or HAC1/SiO2/c-di-GMP (double-adjuvanted vaccine) and evaluated for target-specific immune responses, such as hemagglutination inhibition and hemagglutinin-specific IgG titers, as well as local antibody (IgG and IgA) titers in the bronchoalveolar lavage (BAL). Carbon 12-13 hyperpolarization-activated, cyclic nucleotide-gated K+ 2 Mus musculus 49-53 31768565-0 2020 High Stability and Strong Fluorescence of Carbon Nanodots as Nanosensor for Hg2+ in Environmental Waters. Carbon 42-48 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 76-79 728538-5 1978 Changes in carbon-13 chemical shifts fro ribose C-5" (downfield), C-2" C-3", and C-4" (upfield) and for adenine C-6 and C-8 (upfield) support this model. Carbon 11-17 complement C3 Homo sapiens 71-74 24646186-2 2014 Theory shows that this reaction is initiated by the addition of the para-tolyl radical to either the terminal acetylene carbon (C(4)) or a vinyl carbon (C(1)) leading eventually to two distinct radical intermediates. Carbon 120-126 complement C4A (Rodgers blood group) Homo sapiens 128-132 19305854-7 1978 Paraffinic hydrocarbons detected ranged in carbon length from C15 to C29. Carbon 16-22 placenta associated 8 Homo sapiens 62-65 26382-0 1978 Carbon-13 magnetic resonance of carboxymethylated human carbonic anhydrase B. Carbon 0-6 carbonic anhydrase 2 Homo sapiens 56-76 31629361-0 2020 Decreased Serum Levels of C-Terminal Agrin in Postmenopausal Women Following Resistance Training. Carbon 26-27 agrin Homo sapiens 37-42 31629361-1 2020 Elevated circulating C-terminal agrin fragment (CAF) is a marker of neuromuscular junction degradation and sarcopenia. Carbon 21-22 agrin Homo sapiens 32-37 24646186-2 2014 Theory shows that this reaction is initiated by the addition of the para-tolyl radical to either the terminal acetylene carbon (C(4)) or a vinyl carbon (C(1)) leading eventually to two distinct radical intermediates. Carbon 120-126 heterogeneous nuclear ribonucleoprotein C Homo sapiens 153-157 31631405-4 2020 Furthermore, this direct binding was detected only in the C-terminal ligand binding domain (LBD) of the VDR but not in the N-terminal DNA binding domain (DBD) or the hinge region. Carbon 58-59 vitamin D (1,25-dihydroxyvitamin D3) receptor Mus musculus 104-107 24646186-2 2014 Theory shows that this reaction is initiated by the addition of the para-tolyl radical to either the terminal acetylene carbon (C(4)) or a vinyl carbon (C(1)) leading eventually to two distinct radical intermediates. Carbon 145-151 complement C4A (Rodgers blood group) Homo sapiens 128-132 24646186-2 2014 Theory shows that this reaction is initiated by the addition of the para-tolyl radical to either the terminal acetylene carbon (C(4)) or a vinyl carbon (C(1)) leading eventually to two distinct radical intermediates. Carbon 145-151 heterogeneous nuclear ribonucleoprotein C Homo sapiens 153-157 31968288-1 2020 Methylene tetrahydrofolate reductase (MTHFR) is a flavoprotein, involved in one-carbon pathway and is responsible for folate and homocysteine metabolism. Carbon 80-86 methylenetetrahydrofolate reductase Homo sapiens 0-36 347248-2 1978 The role of carbon catabolite repression in the regulation of catalase A and T formation. Carbon 12-18 catalase A Saccharomyces cerevisiae S288C 62-72 24712804-0 2014 Bond length and electric current oscillation of long linear carbon chains: density functional theory, MpB model, and quantum spin transport studies. Carbon 60-66 AFA1 Homo sapiens 102-105 23176-1 1978 Acetylated ferricytochrome c was employed for the detection of superoxide radicals (O-2) generated both in intact cells and in subcellular fractions of leukocytes. Carbon 1-2 immunoglobulin kappa variable 1D-39 Homo sapiens 84-87 31968288-1 2020 Methylene tetrahydrofolate reductase (MTHFR) is a flavoprotein, involved in one-carbon pathway and is responsible for folate and homocysteine metabolism. Carbon 80-86 methylenetetrahydrofolate reductase Homo sapiens 38-43 31776528-8 2019 Metal-, carbon- and organic-based nanostructures that are used in gum nanocomposites will then be reviewed with respect to their industrial and biomedical applications, to provide a backdrop for future research. Carbon 8-14 OTU deubiquitinase with linear linkage specificity Homo sapiens 66-69 31804802-5 2019 DNMT1 is a multidomain protein with a C-terminal catalytic methyltransferase domain and a large N-terminal regulatory region. Carbon 38-39 DNA methyltransferase 1 Homo sapiens 0-5 16659894-4 1977 The amount of fractionation of stable carbon isotopes by PEP carboxylase from an infinite pool of H(12)CO(3) (-) and H(13)CO(3) (-) was -2.03 per thousand. Carbon 38-44 phosphoenolpyruvate carboxylase 1 Zea mays 57-72 24712804-9 2014 In the case of odd number chains a proposed pi-bond (MpB) model describes unsaturated carbons that introduce a mobile pi-bond that changes dramatically the structure and transport properties of these wires. Carbon 86-93 AFA1 Homo sapiens 53-56 24655227-4 2014 By using a carbon pipette as the tip in the scanning electrochemical microscope (SECM), it can be precisely positioned at the sampling location. Carbon 11-17 TOR signaling pathway regulator Homo sapiens 33-36 31775504-8 2019 By a careful geometric analysis of the oxygen pockets near the substrate binding cleft, the present study identifies the launching sites for oxygenation at the prochiral carbon centers C8, C11, C12, and C15 and the stereochemistry (R/S) of the corresponding products. Carbon 170-176 RNA polymerase III subunit K Homo sapiens 189-192 31775504-8 2019 By a careful geometric analysis of the oxygen pockets near the substrate binding cleft, the present study identifies the launching sites for oxygenation at the prochiral carbon centers C8, C11, C12, and C15 and the stereochemistry (R/S) of the corresponding products. Carbon 170-176 placenta associated 8 Homo sapiens 203-206 300329-7 1977 It was also shown that rat hemolysate cannot substitute for the colony stimulating factor (CSF) needed for the cloning of CFU-C. Carbon 122-127 colony stimulating factor 2 Rattus norvegicus 91-94 31817656-1 2019 Expression of the small GTPase, Ras-related C3 botulinum toxin substrate 1B (RAC1B), a RAC1-related member of the Rho GTPase family, in tumor tissues of pancreatic ductal adenocarcinoma (PDAC) has been shown previously to correlate positively with patient survival, but the underlying mechanism(s) and the target genes involved have remained elusive. Carbon 44-45 Rac family small GTPase 1 Homo sapiens 77-81 300329-8 1977 However, addition of hemolysate, CSF and serum to the soft agar cultures promoted a potentiated rather than an additive growth of CFU-C. Carbon 130-135 colony stimulating factor 2 Rattus norvegicus 33-36 24402456-5 2014 The heavily templated C++ nature of ITK does not facilitate direct interaction between Simulink and ITK; an intermediary is required to convert respective data types and allow intercommunication. Carbon 22-25 IL2 inducible T cell kinase Homo sapiens 36-39 31817245-1 2019 A homoleptic ionic Cu(I) coordination complex that was based on 2,2"-biquinoline ligand functionalized with long alkyl chains (Cu(I)-C18) was used as a precursor to modify a carbon nanofiber paste electrode (Cu-C18/CNF). Carbon 174-180 NPHS1 adhesion molecule, nephrin Homo sapiens 215-218 24489111-4 2014 The Elovl2(-/-) mice displayed substantially decreased levels of 22:6(n-3), DHA, and 22:5(n-6), docosapentaenoic acid (DPA) n-6, and an accumulation of 22:5(n-3) and 22:4(n-6) in both liver and serum, showing that ELOVL2 primarily controls the elongation process of PUFAs with 22 carbons to produce 24-carbon precursors for DHA and DPAn-6 formation in vivo. Carbon 280-287 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 Mus musculus 4-10 31154625-11 2019 Poly I:C stimulation increased mRNA expression of retinoic-acid-inducible protein I (RIG-I), melanoma-differentiation-associated gene 5 (MDA5), IFN-stimulated gene factor 3 (ISG3) complex, and IFN-stimulated genes (IRF7, ISG15, IFIT1, OAS1); nicotine attenuated mRNA expression only in WT cells. Carbon 7-8 DExD/H-box helicase 58 Homo sapiens 85-90 31546385-0 2019 Glucose oxidase immobilized amine terminated multiwall carbon nanotubes/reduced graphene oxide/polyaniline/gold nanoparticles modified screen-printed carbon electrode for highly sensitive amperometric glucose detection. Carbon 55-61 hydroxyacid oxidase 1 Homo sapiens 0-15 31546385-0 2019 Glucose oxidase immobilized amine terminated multiwall carbon nanotubes/reduced graphene oxide/polyaniline/gold nanoparticles modified screen-printed carbon electrode for highly sensitive amperometric glucose detection. Carbon 150-156 hydroxyacid oxidase 1 Homo sapiens 0-15 975043-6 1976 An analysis of the experimentally determined bond lengths indicates that, after the highly reactive epoxide ring, the most reactive positions are at C-1, C-6, C-7, C-11, and C-12. Carbon 149-150 complement C7 Homo sapiens 159-162 975043-6 1976 An analysis of the experimentally determined bond lengths indicates that, after the highly reactive epoxide ring, the most reactive positions are at C-1, C-6, C-7, C-11, and C-12. Carbon 154-155 complement C7 Homo sapiens 159-162 24489111-4 2014 The Elovl2(-/-) mice displayed substantially decreased levels of 22:6(n-3), DHA, and 22:5(n-6), docosapentaenoic acid (DPA) n-6, and an accumulation of 22:5(n-3) and 22:4(n-6) in both liver and serum, showing that ELOVL2 primarily controls the elongation process of PUFAs with 22 carbons to produce 24-carbon precursors for DHA and DPAn-6 formation in vivo. Carbon 280-286 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 Mus musculus 4-10 1267773-0 1976 Carbon-13 magnetic resonance spectra of aortic alpha-elastin in solution, coacervate and fibrous states. Carbon 0-6 elastin Homo sapiens 53-60 24691535-2 2014 The results show that the adsorption of HCN on rGO is generally stronger than that on graphene, which is due to the presence of the active defect sites in rGO, such as the hydroxyl, epoxide, and carboxyl functional groups and even the carbon atom near these groups. Carbon 235-241 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 40-43 131675-13 1976 Elastin isolated from group II aortas is significantly enriched in total lipids, cholesterol (free and esterified) and free fatty acids and contains the widest spectrum of fatty acids (from 11:2 to 22:1) with a significant fraction of total fatty acids as "odd" carbon chains. Carbon 262-268 elastin Homo sapiens 0-7 32042831-6 2019 Results suggested that deleterious variants were mostly enriched in the N- and C-terminal domain of the BRCA1 and BRCA2 C-terminus. Carbon 79-80 BRCA1 DNA repair associated Homo sapiens 104-109 32042831-6 2019 Results suggested that deleterious variants were mostly enriched in the N- and C-terminal domain of the BRCA1 and BRCA2 C-terminus. Carbon 79-80 BRCA2 DNA repair associated Homo sapiens 114-119 31740855-4 2019 Here, we present its cryo-electron microscopy structure, which shows simultaneous engagement of human G protein and bovine beta-arr to the core and phosphorylated tail, respectively, of a single active human chimeric beta2-adrenergic receptor with the C-terminal tail of the arginine vasopressin type 2 receptor (beta2V2R). Carbon 252-253 adrenoceptor beta 2 Homo sapiens 217-242 24211453-0 2014 Direct electrochemistry of myoglobin at reduced graphene oxide-multiwalled carbon nanotubes-platinum nanoparticles nanocomposite and biosensing towards hydrogen peroxide and nitrite. Carbon 75-81 myoglobin Homo sapiens 27-36 31827279-1 2019 The most frequently mutated oncogene in cancer is KRAS, which uses alternative fourth exons to generate two gene products (KRAS4A and KRAS4B) that differ only in their C-terminal membrane-targeting region1. Carbon 168-169 KRAS proto-oncogene, GTPase Homo sapiens 50-54 31827279-1 2019 The most frequently mutated oncogene in cancer is KRAS, which uses alternative fourth exons to generate two gene products (KRAS4A and KRAS4B) that differ only in their C-terminal membrane-targeting region1. Carbon 168-169 KRAS proto-oncogene, GTPase Homo sapiens 123-129 31827279-1 2019 The most frequently mutated oncogene in cancer is KRAS, which uses alternative fourth exons to generate two gene products (KRAS4A and KRAS4B) that differ only in their C-terminal membrane-targeting region1. Carbon 168-169 KRAS proto-oncogene, GTPase Homo sapiens 134-140 1121001-4 1975 An alkyl moiety of 1-8 carbon atoms was substituted for the C-13 to C-20 chain of the PG"s. Carbon 23-29 homeobox C13 Homo sapiens 60-64 24653673-10 2014 Significantly, alterations in one-carbon metabolism that impair PP2A methylation are associated with increased risk for sporadic AD, and enhanced AD-like pathology in animal models. Carbon 34-40 protein phosphatase 2 phosphatase activator Homo sapiens 64-68 31753031-6 2019 This interaction was mediated by the C-terminal tail regions of KIF5A and the third PDZ domain of PSD-95. Carbon 37-38 kinesin family member 5A Homo sapiens 64-69 24328790-0 2014 Phosphorylation of Arabidopsis transketolase at Ser428 provides a potential paradigm for the metabolic control of chloroplast carbon metabolism. Carbon 126-132 Transketolase Arabidopsis thaliana 31-44 31744922-8 2019 A new connection between carbon source and quorum sensing was revealed as Crp was found to regulate production of acyl-homoserine lactones (AHLs) through direct and indirect regulation of genes for AHL synthetases and receptors. Carbon 25-31 C-reactive protein, pentraxin-related Mus musculus 74-77 31744922-11 2019 While Crp has long been appreciated for its role in regulating metabolism of carbon sources in many bacterial species, transcriptional profiling has revealed that this protein regulates many other aspects of bacterial physiology. Carbon 77-83 C-reactive protein, pentraxin-related Mus musculus 6-9 31747582-4 2019 In contrast to in vitro-activated T cells, which display hallmarks of Warburg metabolism, physiologically activated CD8+ T cells displayed greater rates of oxidative metabolism, higher bioenergetic capacity, differential use of pyruvate, and prominent flow of 13C-glucose carbon to anabolic pathways, including nucleotide and serine biosynthesis. Carbon 260-278 CD8a molecule Homo sapiens 116-119 235298-1 1975 When Escherichia coli was grown in a minimum medium with glucose as sole carbon source and a proper level of ammonia, NADP+ specific glutamate dehydrogenase (L-glutamate: NADP+ oxidoreductase (deaminating), ED 1.4.1.4) was induced. Carbon 73-79 glutamate dehydrogenase Escherichia coli 133-156 1129712-1 1975 The effect of frequency of administration of tetrachloride of carbon (CCl4) on synthesis of DNA by hepacytes and cells of the stroma, as well as on composition and magnitude of infiltrates in the liver of mice was studied. Carbon 62-68 chemokine (C-C motif) ligand 4 Mus musculus 70-74 24616559-3 2014 We have observed only one type of IDH in all the strains of S. aureus which dictates the flow of carbon thereby controlling the virulence and biofilm formation, this phenomenon is variable among bacteria. Carbon 97-103 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 34-37 1184287-1 1975 Synthesis, proton magnetic resonance and carbon-13 magnetic resonance characterizations, including complete assignments, are reported for the polyhexapeptide of elastin, HCO-Val(Ala1-Pro2-Gly3-Val4-Gly5-Val6)18-OMe. Carbon 41-47 elastin Homo sapiens 161-168 1123727-4 1975 Simple choline analogs with substituents on the beta-carbon atom were found to be very poor substrates for ChAc. Carbon 53-59 choline O-acetyltransferase Rattus norvegicus 107-111 31752431-2 2019 Here, a flexible integrated sensor based on Au nanoparticle modified copper hydroxide nanograss arrays on flexible carbon fiber cloth (Au@Cu(OH)2/CFC) is fabricated by a facile electrochemical method. Carbon 115-121 tubulin folding cofactor C Homo sapiens 146-149 31591270-9 2019 Point mutations in either the linker or the C-terminal alpha-helix of the PH domain decreased [2-17]ARF1 binding and GAP activity. Carbon 44-45 ADP ribosylation factor 1 Homo sapiens 100-104 24128523-1 2014 A sensitive electrochemical sensor was developed to detect toxic ractopamine using ordered mesoporus carbon (OMC) modified glass carbon electrode (OMC/GCE). Carbon 101-107 aminomethyltransferase Homo sapiens 151-154 31739603-1 2019 The flexible C-terminal hypervariable region distinguishes K-Ras4B, an important proto-oncogenic GTPase, from other Ras GTPases. Carbon 13-14 KRAS proto-oncogene, GTPase Homo sapiens 59-66 31624245-4 2019 Moreover, we found that MYCN mediated the folate cycle via MTHFD2, which contributed one-carbon unit to enhance purine synthesis, and further regulated nucleotide production by PAICS in response to cancer progression. Carbon 89-95 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 59-65 31530751-1 2019 Measured cross sections for the production of the PET isotopes C-10, C-11 and O-15 from carbon and oxygen targets induced by protons (40-220 MeV) and carbon ions (65-430 MeV/u) are presented. Carbon 88-94 RNA polymerase III subunit K Homo sapiens 69-82 31530751-1 2019 Measured cross sections for the production of the PET isotopes C-10, C-11 and O-15 from carbon and oxygen targets induced by protons (40-220 MeV) and carbon ions (65-430 MeV/u) are presented. Carbon 150-156 RNA polymerase III subunit K Homo sapiens 69-82 4369826-0 1974 Carbon-13 magnetic resonance assignments of the repeat peptides of elastin and solvent delineation of carbonyls. Carbon 0-6 elastin Homo sapiens 67-74 4526201-2 1974 Effective correlation times derived from carbon magnetic resonance T(1) values for all the carbon atoms show segmental motion for ring carbon C-10 and in the aliphatic portions of both side chains, while the double bonded portions of the side chains and the ring carbons act as a more rigidly interconnected network. Carbon 41-47 chromosome 12 open reading frame 57 Homo sapiens 142-146 4526201-2 1974 Effective correlation times derived from carbon magnetic resonance T(1) values for all the carbon atoms show segmental motion for ring carbon C-10 and in the aliphatic portions of both side chains, while the double bonded portions of the side chains and the ring carbons act as a more rigidly interconnected network. Carbon 91-97 chromosome 12 open reading frame 57 Homo sapiens 142-146 4526201-2 1974 Effective correlation times derived from carbon magnetic resonance T(1) values for all the carbon atoms show segmental motion for ring carbon C-10 and in the aliphatic portions of both side chains, while the double bonded portions of the side chains and the ring carbons act as a more rigidly interconnected network. Carbon 263-270 chromosome 12 open reading frame 57 Homo sapiens 142-146 4526201-3 1974 Chemical shift changes in the carbon magnetic resonance and proton magnetic resonance spectra upon aggregation suggest that the 5-6 double bond, C-7, and C-9 participate in the aggregation process. Carbon 30-36 complement C7 Homo sapiens 145-148 4526201-3 1974 Chemical shift changes in the carbon magnetic resonance and proton magnetic resonance spectra upon aggregation suggest that the 5-6 double bond, C-7, and C-9 participate in the aggregation process. Carbon 30-36 complement C9 Homo sapiens 154-157 31560011-5 2019 Atomic-scale structural information from STM complement the Raman sensitivity to the single molecular bond to open the way to detailed understanding of these novel carbon nanostructures. Carbon 164-170 sulfotransferase family 1A member 3 Homo sapiens 41-44 24128523-1 2014 A sensitive electrochemical sensor was developed to detect toxic ractopamine using ordered mesoporus carbon (OMC) modified glass carbon electrode (OMC/GCE). Carbon 129-135 aminomethyltransferase Homo sapiens 151-154 31268193-4 2019 This finding is quite unexpected because the initial spin density at the terminal carbon atom of FeC4 + , which serves as the hydrogen acceptor site, is low. Carbon 82-88 spindlin 1 Homo sapiens 53-57 4521798-0 1974 Long-range, pH-dependent effects on the carbon-13 nuclear magnetic resonance spectra of oxytocin. Carbon 40-46 oxytocin/neurophysin I prepropeptide Homo sapiens 88-96 4521798-1 1974 The effects of hydrogen ion concentrations on the carbon-13 nuclear magnetic resonance spectra of oxytocin were investigated. Carbon 50-56 oxytocin/neurophysin I prepropeptide Homo sapiens 98-106 4521798-3 1974 A change of the state of protonation of the N-terminal amino group of oxytocin is accompanied by changes in chemical shifts of carbon-13 nuclei of amino-acid residues located in the 20-membered ring of the hormone. Carbon 127-133 oxytocin/neurophysin I prepropeptide Homo sapiens 70-78 31268193-6 2019 Thus, a highly localized spin density is generated in situ at the terminal carbon atom. Carbon 75-81 spindlin 1 Homo sapiens 25-29 24333266-1 2014 The current study was conducted to elucidate the effect of genetic variations in one-carbon metabolism on the epigenetic regulation of major histocompatibility complex II transactivator (MHC2TA), reduced folate carrier 1 (RFC1/SLC19A1) and human leukocyte antigen (HLA)-DR in systemic lupus erythematosus (SLE). Carbon 85-91 class II major histocompatibility complex transactivator Homo sapiens 187-193 31597303-0 2019 Design and Fabrication of CMOS Microstructures to Locally Synthesize Carbon Nanotubes for Gas Sensing. Carbon 69-75 MOS proto-oncogene, serine/threonine kinase Homo sapiens 26-30 31597303-1 2019 Carbon nanotubes (CNTs) can be grown locally on custom-designed CMOS microstructures to use them as a sensing material for manufacturing low-cost gas sensors, where CMOS readout circuits are directly integrated. Carbon 0-6 MOS proto-oncogene, serine/threonine kinase Homo sapiens 64-68 17731763-2 1969 The solubilities at 25 degrees C of the normal C(9) (220 parts per billion) and C(10) (52 parts per billion) alkanes decrease with increasing carbon number. Carbon 142-148 complement C9 Homo sapiens 47-51 31597303-1 2019 Carbon nanotubes (CNTs) can be grown locally on custom-designed CMOS microstructures to use them as a sensing material for manufacturing low-cost gas sensors, where CMOS readout circuits are directly integrated. Carbon 0-6 MOS proto-oncogene, serine/threonine kinase Homo sapiens 165-169 24333266-12 2014 To conclude, one-carbon genetic variants influence epigenetic of MHC2TA and RFC1, thus contributing to phenotypic heterogeneity of SLE. Carbon 17-23 class II major histocompatibility complex transactivator Homo sapiens 65-71 24132521-3 2014 A COP-Compost model, which couples an organic carbon (OC) module and an organic pollutant (OP) module and which simulates the changes of organic matter, organic pollutants and the microbial activities during the composting process, has been proposed and calibrated for a first set of OP in a previous study. Carbon 46-52 caspase recruitment domain family member 16 Homo sapiens 2-5 31427741-3 2019 Here, we show that coupling to a magnetic texture can induce both a strong spin-orbit coupling of 1.1 meV and a Zeeman effect in a carbon nanotube. Carbon 131-137 spindlin 1 Homo sapiens 75-79 31516609-8 2019 These findings indicate that compared with low-LET X-ray irradiation, high-LET carbon ions possess higher biological efficacy in inhibiting the invasive ability of Tca8113 cells via reduction of VEGF, MMP-2 and MMP-9 expression. Carbon 79-85 matrix metallopeptidase 9 Homo sapiens 211-216 31402576-3 2019 Carbon dots (C-dots) functionalized with the VEGF aptamer are introduced and the hybrid nanoparticles are used for ocular nanomedicine. Carbon 0-6 vascular endothelial growth factor A Mus musculus 45-49 31569820-2 2019 Structurally, Hsp70s are composed of an N-terminal nucleotide binding domain (NBD) which exhibits ATPase activity, and a C-terminal substrate binding domain (SBD). Carbon 121-122 heat shock protein family A (Hsp70) member 4 Homo sapiens 14-19 31616819-3 2019 In the present study, we have found that in toluene the catalytic activity of tyrosinase deposited onto coated mesoporous carbon is significantly enhanced when the support is precoated with polyethylenimine. Carbon 122-128 tyrosinase Homo sapiens 78-88 31449383-0 2019 Detection of Spin Reversal via Kondo Correlation in Hybrid Carbon Nanotube Quantum Dots. Carbon 59-65 spindlin 1 Homo sapiens 13-17 31461617-2 2019 Herein, we report the synthesis of bimetallic CoxNi1-xP ultrafine nanocrystals supported on carbon nanofibers (CoxNi1-xP/CNF) and explore their use as positive electrode materials of asymmetric supercapacitors. Carbon 92-98 NPHS1 adhesion molecule, nephrin Homo sapiens 121-124 31732897-0 2019 Combined Irradiation by Gamma Rays and Carbon Nuclei Increases the C/EBP-beta LIP Isoform Content in the Pituitary Gland of Rats. Carbon 39-45 CCAAT/enhancer binding protein beta Rattus norvegicus 67-77 31237287-6 2019 The exact empirical formula of the MPG-MOFs is derived as [RuxRh3-x(BTC)2-a(OAc)b(Cl)c]. Carbon 7-8 N-methylpurine DNA glycosylase Homo sapiens 35-38 31555090-8 2019 However, a monoclonal antibody (CB-beta-1) recognized CaMKII-beta but also cross-reacted with the C-terminal tail of Cx36, making localization analyses with this antibody inaccurate. Carbon 32-33 gap junction protein, delta 2 Mus musculus 117-121 31299145-8 2019 It paves a futuristic path to investigate the GSAP-APP C-99 binding in detail and accentuates the role of GSAP in the beta-amyloid pathway. Carbon 55-56 gamma-secretase activating protein Homo sapiens 46-50 31361119-4 2019 The carbonized PAN matrix with an N-doped carbon ring structure could effectively confine SeS2 in the form of small molecules and regulate its electronic structure. Carbon 4-10 secernin 2 Homo sapiens 90-94 31361119-5 2019 The superior sodium/potassium storage performance of the OC/SeS2 composite electrodes stems from their rational chemical structure design, including high electrical conductivity of the N-doped organic carbon network and chemical binding with SeS2 molecules. Carbon 201-207 secernin 2 Homo sapiens 60-64 31243089-3 2019 Macrophages from TAK1-deficient mice underwent cell death in response to LPS and poly(I:C), which took place in a manner dependent on TLR/TRIF-induced active Caspase8-mediated cleavage of gasdermin D, known as an executioner of pyroptosis. Carbon 88-89 gasdermin D Mus musculus 188-199 31292484-0 2019 Preparation of the heterojunction catalyst N-doping carbon quantum dots/P25 and its visible light photocatalytic activity. Carbon 52-58 tubulin polymerization promoting protein Homo sapiens 72-75 31292484-1 2019 N-doping carbon quantum dots were successfully loaded on P25 nanoparticles (denoted as N-CDs/P25) by facile hydrothermal process, and their morphology and chemical structure were systematically studied. Carbon 9-15 tubulin polymerization promoting protein Homo sapiens 57-60 31292484-1 2019 N-doping carbon quantum dots were successfully loaded on P25 nanoparticles (denoted as N-CDs/P25) by facile hydrothermal process, and their morphology and chemical structure were systematically studied. Carbon 9-15 tubulin polymerization promoting protein Homo sapiens 93-96 31338089-4 2019 We found that total nitrogen and soil organic carbon were higher when cover crops were killed by frost compared to rolling and glyphosate termination treatments, while cover crop biomass was positively correlated to soil carbon and C:N ratio. Carbon 46-52 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 76-80 31073727-7 2019 RESULTS: VLC-PUFA-SM species having 28-34 carbon fatty acids were detected in sperm samples, with 28 and 30 carbon VLC-PUFA as most the abundant. Carbon 42-48 pumilio RNA binding family member 3 Homo sapiens 13-17 31158691-3 2019 Here, we report a low-cost and scalable strategy to create flexible anodes of N-doped carbon nanofiber-confined porous silica (p-SiO2@N-CNF) by developing a sol-gel electrospinning process followed by carbonization. Carbon 86-92 NPHS1 adhesion molecule, nephrin Homo sapiens 136-139 31179470-4 2019 In this manuscript, the molecule 4,4""-dibromo-5"-(4-chlorophenyl)-1,1":3",1""-terphenyl incorporated two Br terminals and one Cl terminal has been used to demonstrate different reactivities of a C-Cl bond and a C-Br bond via the hierarchical activation of the C-Br bond and the C-Cl bond on Cu(111). Carbon 127-128 carbonyl reductase 1 Homo sapiens 212-216 31179470-4 2019 In this manuscript, the molecule 4,4""-dibromo-5"-(4-chlorophenyl)-1,1":3",1""-terphenyl incorporated two Br terminals and one Cl terminal has been used to demonstrate different reactivities of a C-Cl bond and a C-Br bond via the hierarchical activation of the C-Br bond and the C-Cl bond on Cu(111). Carbon 127-128 carbonyl reductase 1 Homo sapiens 261-265 30928792-5 2019 Further analysis showed that ammonia-oxidizing bacteria (AOB) and nitrite oxidizing bacteria (NOB) in the O1 and O2 tanks together contributed to the conversion of ammonia nitrogen to nitrate, but the process of heterotrophic denitrification was inhibited in the A1 and A2 tanks because of insufficient carbon sources. Carbon 303-309 immunoglobulin kappa variable 2D-40 Homo sapiens 106-115 31195953-0 2019 CircRNA-9119 suppresses poly I:C induced inflammation in Leydig and Sertoli cells via TLR3 and RIG-I signal pathways. Carbon 0-1 DEAD/H box helicase 58 Mus musculus 95-100 31163587-5 2019 It was found that the elevated temperature contributed to increasing saturated components (e.g., C-F2 and C-F3) and decreasing unsaturated components (e.g., C-C and C-CF), thus enhancing the fluorine-to-carbon (F/C) ratio. Carbon 203-209 ATPase H+ transporting accessory protein 1 Homo sapiens 97-101 30711102-2 2019 The biosensor architecture is based on tyrosinase (Tyrase) immobilization on glassy carbon electrode modified by a nanocomposite consisting of gold nanoparticles (AuNP) synthesized by a green method and poly(8-anilino-1-naphthalene sulphonic acid) modified glassy carbon electrode. Carbon 84-90 tyrosinase Homo sapiens 39-49 30711102-2 2019 The biosensor architecture is based on tyrosinase (Tyrase) immobilization on glassy carbon electrode modified by a nanocomposite consisting of gold nanoparticles (AuNP) synthesized by a green method and poly(8-anilino-1-naphthalene sulphonic acid) modified glassy carbon electrode. Carbon 84-90 tyrosinase Homo sapiens 51-57 30844476-4 2019 The design of the glucose ligands on Gluc-CDDP/m was engineered to control the conjugation via the carbon 6 of the glucose moieties, as well as the ligand density on the poly (ethylene glycol) (PEG) shell of the micelles. Carbon 99-105 glucosylceramidase beta 3 (gene/pseudogene) Homo sapiens 37-41 30877197-1 2019 ATP-citrate lyase (ACLY) is a major source of nucleocytosolic acetyl-CoA, a fundamental building block of carbon metabolism in eukaryotes. Carbon 106-112 ATP citrate lyase Homo sapiens 0-17 30877197-1 2019 ATP-citrate lyase (ACLY) is a major source of nucleocytosolic acetyl-CoA, a fundamental building block of carbon metabolism in eukaryotes. Carbon 106-112 ATP citrate lyase Homo sapiens 19-23 30969031-5 2019 Carbon-based alloy-type composites (CAC) have been extensively applied in the effective construction of anodes that improved electrochemical performance, as the carbon component could alleviate the volume change and increase the conductivity. Carbon 0-6 carbonic anhydrase 2 Homo sapiens 36-39 30969031-5 2019 Carbon-based alloy-type composites (CAC) have been extensively applied in the effective construction of anodes that improved electrochemical performance, as the carbon component could alleviate the volume change and increase the conductivity. Carbon 161-167 carbonic anhydrase 2 Homo sapiens 36-39 30969031-8 2019 The crucial roles and working mechanism of the carbon matrix in CAC anodes are discussed in depth. Carbon 47-53 carbonic anhydrase 2 Homo sapiens 64-67 30743972-0 2019 Characterization of dissolved organic carbon in shallow groundwater of chronic kidney disease affected regions in Sri Lanka. Carbon 38-44 sorcin Homo sapiens 114-117 13357337-0 1956 Determination of the excretion and the tissue distribution of carboxyl carbon in the rat after administration of C14 carboxyl acetylsalicylic acid. Carbon 71-77 anti-Mullerian hormone receptor type 2 Rattus norvegicus 113-116 14381390-0 1955 Origin of glucose and glycogen carbons formed from C14-labeled pyruvate by livers of normal and diabetic rats. Carbon 31-38 anti-Mullerian hormone receptor type 2 Rattus norvegicus 51-54 13000060-1 1952 In tissue cultures of C-57 black mouse heart and sarcoma T-241, beta-2-thienyl-DL-alanine acts specifically as a phenylalanine antagonist. Carbon 22-23 hemoglobin, beta adult minor chain Mus musculus 64-70 33823466-1 2021 A novel amperometric aptasensor for the specific detection of cardiac troponin I (cTnI) was constructed by using screen-printed carbon electrodes coated with a carboxyethylsilanetriol-modified graphene oxide derivative as transduction element. Carbon 128-134 troponin I3, cardiac type Homo sapiens 62-80 33823466-1 2021 A novel amperometric aptasensor for the specific detection of cardiac troponin I (cTnI) was constructed by using screen-printed carbon electrodes coated with a carboxyethylsilanetriol-modified graphene oxide derivative as transduction element. Carbon 128-134 troponin I3, cardiac type Homo sapiens 82-86 33497733-7 2021 In ALV-J and poly(I:C) stimulated CEFs cells, the expression level of STAT1, IFN-alpha, IFN-beta, TLR3 and TLR7 were increased after IRF7 overexpressed, while the results were just the opposite after IRF7 interfered, which indicating that IRF7 may be associated with Toll-like receptor signaling pathway and JAK-STAT signaling pathway. Carbon 20-22 signal transducer and activator of transcription 1 Homo sapiens 70-75 34011531-7 2021 Docking into MAO B crystal structure suggested that even though both the isomers occupied its active site, only the orientation of RP-101075 presented the C-H on the a-carbon that was ideal for the C-H bond cleavage, which is a requisite for oxidative deamination. Carbon 168-174 monoamine oxidase B Homo sapiens 13-18 33878262-3 2021 Herein, we propose a facile one-pot electrospinning-derived highly lithiophilic nanocopper-reinforced three-dimensional-structured carbon nanofiber (Cu-CNF) as functional scaffold to stabilize the Li metal. Carbon 131-137 NPHS1 adhesion molecule, nephrin Homo sapiens 152-155 33903254-8 2021 In the Indus, dust and black carbon degrade the snow/ice albedos [S. M. Skiles, M. Flanner, J. M. Cook, M. Dumont, T. H. Painter, Nat. Carbon 29-35 bromodomain containing 2 Homo sapiens 130-133 33938102-2 2021 Here we developed a modular in vitro platform for the continuous conversion of CO 2 into complex multi-carbon compounds, such as monoterpenes (C10), sesquiterpenes (C15) and polyketides. Carbon 103-109 placenta associated 8 Homo sapiens 165-168 33547664-5 2021 AtALT1 and AtALT4 overexpression in leaves and seeds resulted in the accumulation of 12-14 carbon-length fatty acids and 6-8 carbon-length fatty acids, respectively. Carbon 91-98 Thioesterase superfamily protein Arabidopsis thaliana 11-17 33931891-5 2021 Several rearrangements of the photosynthetic machinery were observed in both species, differing from those described for the model organism Chlamydomonas reinhardtii, where adaptation to carbon availability is mainly controlled by the translational repressor NAB1. Carbon 187-193 uncharacterized protein Chlamydomonas reinhardtii 259-263 33860978-1 2021 An efficient and attractive Co/organophotoredox dual catalysis protocol has been developed allowing the stereoselective access to a wide variety of syn-configured 1,3-diols featuring quaternary carbon centers. Carbon 194-200 synemin Homo sapiens 148-151 33856705-5 2021 Major structural changes were also observed during CLSM imaging, which were greatly pronounced in pork samples oven cooked for 15 and 20 h (O-C-15 and O-C-20). Carbon 51-52 placenta associated 8 Homo sapiens 142-146 33877179-6 2021 Organo and alkoxide ligands are derived from solvent media and the trends in reactivity reveal that combination of the pKa and BDE of the C-H of the respective solvent substrates are important. Carbon 138-139 homeobox D13 Homo sapiens 127-130 33759061-1 2021 A flexible nano-engineered natural mineral (carbon dot doped natural microcline) based membrane (MCPV) has been developed, which can efficiently detect the presence of hexavalent chromium (Cr6+) and trivalent iron (Fe3+) ions in water by altering its fluorescence emission. Carbon 44-50 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 189-192 33723074-8 2021 In parallel, Crtc also promoted the expression of genes involved in one-carbon (1-C) metabolism. Carbon 72-78 CREB-regulated transcription coactivator Drosophila melanogaster 13-17 33656325-2 2021 In this work, Cu-doped cobalt oxide and porous carbon nanocomposites (CuCo(O)@PCNs) were synthesized from double-layered ZIF-8@ZIF-67 and GOx was loaded in the porous carbon to form a CuCo(O)/GOx@PCNs hybrid nanozyme. Carbon 47-53 hydroxyacid oxidase 1 Homo sapiens 138-141 33707459-0 2021 Spin-state-dependent electrical conductivity in single-walled carbon nanotubes encapsulating spin-crossover molecules. Carbon 62-68 spindlin 1 Homo sapiens 0-4 33707459-0 2021 Spin-state-dependent electrical conductivity in single-walled carbon nanotubes encapsulating spin-crossover molecules. Carbon 62-68 spindlin 1 Homo sapiens 93-97 33485578-3 2021 In this study, a metal oxide hybrid with nitrogen-doped carbon dots (MFNCDs) that showed intrinsic peroxidase-like activity was synthesized and used as a catalyst instead of GOx to oxidize 3,3",5,5"-tetramethylbenzidine (TMB) to blue-emitting oxidized TMB (oxTMB) in the presence of hydrogen peroxide (H2O2). Carbon 56-62 hydroxyacid oxidase 1 Homo sapiens 174-177 33400690-7 2021 Metabolome analysis revealed that this TNIK inhibitor redirected the metabolic network from carbon flux towards lipid accumulation in OS cells. Carbon 92-98 TRAF2 and NCK interacting kinase Homo sapiens 39-43 33485214-3 2021 Here, we construct Poly I: C-encapsulated poly (lactic-co-glycolic acid) nanoparticles (PLP NPs) with a slow release profile. Carbon 27-28 proteolipid protein 1 Homo sapiens 88-91 32949301-5 2021 Cells were basally stimulated with agonists Pam2CSK4 (Pam; TLR2), polyinosinic/polycytidylic acid (Poly I:C; TLR3), and lipopolysaccharide (LPS; TLR4) for 24 h. Supernatants were evaluated with ELISA for cytokines TNFalpha, IL-6, and IL-1beta. Carbon 0-1 peptidylglycine alpha-amidating monooxygenase Homo sapiens 44-52 32949301-5 2021 Cells were basally stimulated with agonists Pam2CSK4 (Pam; TLR2), polyinosinic/polycytidylic acid (Poly I:C; TLR3), and lipopolysaccharide (LPS; TLR4) for 24 h. Supernatants were evaluated with ELISA for cytokines TNFalpha, IL-6, and IL-1beta. Carbon 0-1 peptidylglycine alpha-amidating monooxygenase Homo sapiens 44-47 33543976-0 2021 Long-Distance Ultrafast Spin Transfer over a Zigzag Carbon Chain Structure. Carbon 52-58 spindlin 1 Homo sapiens 24-28 33543976-2 2021 The spin-density transfer takes place between two Ni atoms and over a 40-atom-long zigzag carbon chain. Carbon 90-96 spindlin 1 Homo sapiens 4-8 33452755-9 2021 Moreover, they repressed poly(I:C)-induced phosphorylation of IFN regulatory factor (IRF) 3 and signal transducers and activators of transcription (STAT) 1, which is involved in Janus kinase (JAK)/STAT signaling. Carbon 32-34 signal transducer and activator of transcription 1 Mus musculus 96-155 33452755-9 2021 Moreover, they repressed poly(I:C)-induced phosphorylation of IFN regulatory factor (IRF) 3 and signal transducers and activators of transcription (STAT) 1, which is involved in Janus kinase (JAK)/STAT signaling. Carbon 32-34 signal transducer and activator of transcription 1 Mus musculus 148-152 33505415-0 2020 The Molecular Regulation of Carbon Sink Strength in Grapevine (Vitis vinifera L.). Carbon 28-34 tribbles pseudokinase 3 Homo sapiens 35-39 30887976-2 2019 In this research, we have successfully designed and synthesized a hierarchical three-dimensional cobalt sulfide encapsulated carbon nanotube/carbon nanofiber (Co9S8@CNT/CNF) composite, resulting in a high-performance supercapacitor with an unrivalled capacitance of 1580 F g-1 at a current density of 1 A g-1. Carbon 141-147 NPHS1 adhesion molecule, nephrin Homo sapiens 169-172 30803063-3 2019 The as-prepared single atoms, supported by N-doped carbon flake arrays grown on carbon nanofibers assembly (M SA@NCF/CNF), demonstrate the dual characteristics of excellent catalytic activity (reversible oxygen overpotential of 0.75 V) and high stability, owing to the greatly improved active sites" accessibility and optimized single-sites/pore-structures correlations. Carbon 51-57 NPHS1 adhesion molecule, nephrin Homo sapiens 117-120 30803063-3 2019 The as-prepared single atoms, supported by N-doped carbon flake arrays grown on carbon nanofibers assembly (M SA@NCF/CNF), demonstrate the dual characteristics of excellent catalytic activity (reversible oxygen overpotential of 0.75 V) and high stability, owing to the greatly improved active sites" accessibility and optimized single-sites/pore-structures correlations. Carbon 80-86 NPHS1 adhesion molecule, nephrin Homo sapiens 117-120 30786131-5 2019 The reaction is thought to proceed through a syn intramolecular carbonickelation across a 2-substituted indole followed by a diastereoretentive reductive elimination of the carbon-iodine bond. Carbon 64-70 synemin Homo sapiens 45-48 33120307-1 2021 In the present work, an innovative electrochemical sensor was fabricated based on poly toluidine blue modified glassy carbon electrode (PTB-GCE). Carbon 118-124 polypyrimidine tract binding protein 1 Homo sapiens 136-139 24338968-8 2014 Using our optimized method, stable carbon isotope ratios can be reliably measured in samples with concentrations of PAHs down to 0.05-0.1 ng muL(-1). Carbon 35-41 mitochondrial E3 ubiquitin protein ligase 1 Homo sapiens 141-147 33445177-3 2021 Stimulation with Poly I:C up-regulated C3aR mRNA and intra- and extracellular expression in NHEKs which showed functional relevance by up-regulating CXCL10 and down-regulating C3 expression in response to C3a. Carbon 24-25 C-X-C motif chemokine ligand 10 Homo sapiens 149-155 33445177-3 2021 Stimulation with Poly I:C up-regulated C3aR mRNA and intra- and extracellular expression in NHEKs which showed functional relevance by up-regulating CXCL10 and down-regulating C3 expression in response to C3a. Carbon 24-25 complement C3 Homo sapiens 39-42 30883104-15 2019 The carbon paste electrodes can be used as bifunctional amperometric and fluorescence sensors for recognition of Hg2+. Carbon 4-10 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 113-116 30960577-4 2019 As expected, SWCNT composites based on the platinum acetylides embedded polymers displayed a higher power factor (130.7 +- 3.8 muW m-1 K-2) at ambient temperature than those without platinum acetylides (59.5 +- 0.7 muW m-1 K-2) under the same conditions. Carbon 13-18 RBPJ pseudogene 3 Homo sapiens 135-138 33255035-5 2021 The MnO-Mn3O4@rGO modified glassy carbon electrode provided a wide linear response from 0.004 to 17 mM, a low detection limit of 0.1 muM, and high sensitivity of 274.15 muA mM-1 cm-2. Carbon 34-40 Mix1 homeobox-like 1 (Xenopus laevis) Mus musculus 173-182 30960577-4 2019 As expected, SWCNT composites based on the platinum acetylides embedded polymers displayed a higher power factor (130.7 +- 3.8 muW m-1 K-2) at ambient temperature than those without platinum acetylides (59.5 +- 0.7 muW m-1 K-2) under the same conditions. Carbon 13-18 RBPJ pseudogene 3 Homo sapiens 223-226 23944933-6 2014 Knockdown of IL-17 receptor (IL-17R) E, the specific receptor for IL-17C, using IL-17RE small interfering RNA, attenuated polyI:C-induced hBD2, CSF3, and S100A12 expression, without any reduction of polyI:C-induced IL-17C expression, which suggest that IL-17C enhances hBD2, CSF, and S100A12 expression in an autocrine/paracrine manner in NHBE cells. Carbon 128-129 interleukin 17C Homo sapiens 66-72 23944933-7 2014 Knockdown of IL-17C also decreased polyI:C-induced hBD2, CSF3, and S100A12 expression. Carbon 18-19 colony stimulating factor 3 Homo sapiens 57-61 30893831-1 2019 The consideration of the disposition of minima of electron density and electrostatic potential along the line between non-covalently bound atoms in systems with Hal- CH3-Y (Hal- = Cl, Br; Y = N, O) fragments allowed to prove that the carbon atom in methyl group serves as an electrophilic site provider. Carbon 236-242 histidine ammonia-lyase Homo sapiens 161-164 24498916-3 2014 Ducloudine C (1) is the first aconitine-type C19-diterpenoid alkaloid with a C=O group at C-3 and a C=C bond between C-1 and C-2. Carbon 11-12 heterogeneous nuclear ribonucleoprotein C Homo sapiens 117-128 30686752-7 2019 Docking simulations also implied that 6 interacted with hMAO-A at Phe208 and with hMAO-B at Ile199 by carbon hydrogen bondings. Carbon 102-108 monoamine oxidase B Homo sapiens 82-88 30772128-4 2019 Furthermore, selected compounds 3, 8, 9, 19 and 21 with spatial distances between the next carbon to Dpa and the next carbon to cyclam within the range of 6.5-7.5 A showed potent binding affinity selective for CXCR4 with IC50 values of 1.6, 7.9, 5.7, 3.5 and 4.5 nM, respectively, with corresponding high anti-HIV activity with EC50s of 28, 13, 21, 28 and 61 nM, respectively, in the presence of zinc (II) ion. Carbon 91-97 C-X-C motif chemokine receptor 4 Homo sapiens 210-215 30772128-4 2019 Furthermore, selected compounds 3, 8, 9, 19 and 21 with spatial distances between the next carbon to Dpa and the next carbon to cyclam within the range of 6.5-7.5 A showed potent binding affinity selective for CXCR4 with IC50 values of 1.6, 7.9, 5.7, 3.5 and 4.5 nM, respectively, with corresponding high anti-HIV activity with EC50s of 28, 13, 21, 28 and 61 nM, respectively, in the presence of zinc (II) ion. Carbon 118-124 C-X-C motif chemokine receptor 4 Homo sapiens 210-215 33263410-1 2020 We describe herein a Cu(OTf)2 catalyzed oxidative arylation of a tertiary carbon-containing substrate including aryl malononitriles, 3-aryl benzofuran-2-ones, and 3-aryl oxindoles. Carbon 74-80 POU class 2 homeobox 2 Homo sapiens 21-29 33256396-4 2020 To explain the formation of [an + 2H]+ and [xm + 2H]+, hydrogen attachment to the carbonyl carbon atom on the peptide backbone is proposed to initiate Calpha-C bond cleavage. Carbon 82-88 carbonic anhydrase 2 Homo sapiens 151-159 24141941-4 2014 CLPP results showed that bacterial communities utilized the carbon guilds similarly between sites within the three lakes. Carbon 60-66 caseinolytic mitochondrial matrix peptidase proteolytic subunit Homo sapiens 0-4 33167619-3 2020 We find that although the CISS effect is entirely attributed in the literature to molecular spin filtering, spin-orbit coupling being partially inherited from the metal electrodes plays an important role in our calculations on ideal carbon helices, even though this effect cannot explain the experimental conductance results. Carbon 233-239 spindlin 1 Homo sapiens 108-112 30599289-0 2019 Targeting carbon nanotubes based on IGF-1R for photothermal therapy of orthotopic pancreatic cancer guided by optical imaging. Carbon 10-16 insulin like growth factor 1 receptor Homo sapiens 36-42 24515454-1 2014 Mammalian glutamate dehydrogenase (GDH) catalyzes the reversible inter-conversion of glutamate to alpha-ketoglutarate and ammonia, interconnecting carbon skeleton and nitrogen metabolism. Carbon 147-153 glutamate dehydrogenase 1 Homo sapiens 10-33 30476532-4 2019 Non-cytotoxic doses of carbon nanoparticles but not of bigger carbon particles led to an irreversible reduction of the proliferative capacity accompanied by the accumulation of the cell cycle blocking proteins p21 and p16 as well as a loss of both redox sensitive histone deacetylase SIRT1 and connexin-43. Carbon 23-29 sirtuin 1 Homo sapiens 284-289 30609552-0 2019 Molecularly imprinted polymer nano-sphere/multi-walled carbon nanotube coated glassy carbon electrode as an ultra-sensitive voltammetric sensor for picomolar level determination of RDX. Carbon 85-91 radixin Homo sapiens 181-184 33335403-6 2020 The expression of some apoptotic and autophagy-related genes such as Bax, Bcl2, Beclin1 and ATG7 was significantly induced by carbon-ion beam irradiation alone and was further enhanced when the beam was combined with 5-FU. Carbon 126-132 beclin 1 Homo sapiens 80-87 33364984-1 2020 5,10-Methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism is considered as a predisposition and promising genetic candidate to major depressive disorder (MDD), as it is associated with impaired one-carbon cycles, which may be involved in the pathogenesis of depression. Carbon 213-219 methylenetetrahydrofolate reductase Homo sapiens 0-40 33364984-1 2020 5,10-Methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism is considered as a predisposition and promising genetic candidate to major depressive disorder (MDD), as it is associated with impaired one-carbon cycles, which may be involved in the pathogenesis of depression. Carbon 213-219 methylenetetrahydrofolate reductase Homo sapiens 42-47 30609552-0 2019 Molecularly imprinted polymer nano-sphere/multi-walled carbon nanotube coated glassy carbon electrode as an ultra-sensitive voltammetric sensor for picomolar level determination of RDX. Carbon 55-61 radixin Homo sapiens 181-184 24515454-1 2014 Mammalian glutamate dehydrogenase (GDH) catalyzes the reversible inter-conversion of glutamate to alpha-ketoglutarate and ammonia, interconnecting carbon skeleton and nitrogen metabolism. Carbon 147-153 glutamate dehydrogenase 1 Homo sapiens 35-38 24307367-1 2013 A new biomimetic functional system having an impure multiwalled carbon nanotube (MWCNT-Fe)-chitosan biopolymer (H2N-CHIT) chemically modified glassy carbon electrode (GCE/[MWCNT-Fe:H2N-CHIT]) has been developed and demonstrated efficient hydrogen peroxide electrocatalytic and electrochemical sensing applications in pH 7 phosphate buffer solution (PBS). Carbon 149-155 chitinase 1 Homo sapiens 116-120 30534771-2 2019 The D-RFP was proposed by embedding glycine-derived carbon dots (CDs) (lambdaem = 400 nm) into silica nanoparticles and covalently linking CdTe quantum dots (QDs) (lambdaem = 600 nm) onto the surface of silica nanoparticles. Carbon 52-58 tripartite motif containing 27 Homo sapiens 6-9 33015733-0 2020 Impairment of the mitochondrial one-carbon metabolism enzyme SHMT2 causes a novel brain and heart developmental syndrome. Carbon 36-42 serine hydroxymethyltransferase 2 Homo sapiens 61-66 32721686-5 2020 Mechanistic exploration reveals that SAs can bind with adenylate cyclase at a low dose and dihydropteroate synthase at a high dose, respectively, activating the stimulatory and inhibitory signaling pathway to influence carbon catabolite repression in diauxic growth, which can interfere with the metabolism of tryptone and yeast extract to ultimately trigger hormesis. Carbon 219-225 adenylate cyclase Saccharomyces cerevisiae S288C 55-72 24476296-3 2013 Carbon substitution for Se (C(Se)) results in an opening of a sizable surface Dirac gap (up to 82 meV), while the Fermi level remains inside the bulk gap and close to the Dirac point at moderate doping concentrations. Carbon 0-6 choreoathetosis/spasticity, episodic (paroxysmal choreoathetosis/spasticity) Homo sapiens 28-33 33266095-1 2020 The vacuum hot-rolled SUS314/Q235 stainless steel clad plate has many drawbacks including serious interface alloy element diffusion, stainless steel cladding"s sensitization, and carbon steel substrate"s low strength. Carbon 179-185 alcohol dehydrogenase iron containing 1 Homo sapiens 11-14 30476185-3 2019 Using a field-effect transistor (FET)-type biosensor based on carbon nanofibers, in the present study we demonstrate that Haa1 and War1 directly bind to various weak acid anions with different affinities. Carbon 62-68 Haa1p Saccharomyces cerevisiae S288C 122-126 30602064-4 2019 Quaternary carbons are established at high Fsp3 attached-ring junctures and the carboxylate directing group can be removed after coupling. Carbon 11-18 NIPA magnesium transporter 1 Homo sapiens 43-47 24182322-2 2013 The latter reaction is valuable for the stereoselective C-C bond formation by condensation of HCN with carbonyl compounds. Carbon 56-57 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 94-97 30679275-2 2019 Our recent work uncovered a requirement for cytoplasmic arginine methylation during Wnt signaling through the activity of protein arginine methyltransferase 1 (PRMT1), which transfers one-carbon groups from SAM to many protein substrates. Carbon 188-194 protein arginine methyltransferase 1 Homo sapiens 122-158 30679275-2 2019 Our recent work uncovered a requirement for cytoplasmic arginine methylation during Wnt signaling through the activity of protein arginine methyltransferase 1 (PRMT1), which transfers one-carbon groups from SAM to many protein substrates. Carbon 188-194 protein arginine methyltransferase 1 Homo sapiens 160-165 33179489-7 2020 The use of a simple, commercially available ligand, PAd3, is key to this water-assisted mechanism by promoting coordinative unsaturation in catalytic intermediates responsible for the heterolytic activation of strong element-hydrogen bonds, which enables broad compatibility of carbon-heteroatom cross-coupling reactions with sensitive substrates and functionality. Carbon 278-284 peptidyl arginine deiminase 3 Homo sapiens 52-56 24182322-2 2013 The latter reaction is valuable for the stereoselective C-C bond formation by condensation of HCN with carbonyl compounds. Carbon 58-59 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 94-97 24096940-0 2013 Controlled fabrication and photocatalytic properties of a three-dimensional ZnO nanowire/reduced graphene oxide/CdS heterostructure on carbon cloth. Carbon 135-141 CDP-diacylglycerol synthase 1 Homo sapiens 112-115 33211956-3 2020 Here were present a Co9S8@MoS2 core-shell heterostructure anchored to a carbon nanofiber (Co9S8@MoS2/CNF), developed as an interlayer for suppressing the shuttle effect of LiPSs. Carbon 72-78 NPHS1 adhesion molecule, nephrin Homo sapiens 101-104 33097666-8 2020 These findings demonstrate compartmentalization of Ca2+ signals dictates the odorant receptor OR2W3-induced ASM relaxation and identify a previously unrecognized E-C coupling mechanism that could be exploited in the development of therapeutics to treat obstructive lung diseases. Carbon 51-52 olfactory receptor family 2 subfamily W member 3 Homo sapiens 94-99 30717430-0 2019 Harvested Wood Products as a Carbon Sink in China, 1900-2016. Carbon 29-35 tribbles pseudokinase 3 Homo sapiens 36-40 30906627-7 2019 Methylenetetrahydrofolate dehydrogenase (MTHFD2), a dual-functional metabolic enzyme, is involved in the one-carbon metabolism of folate in mitochondria. Carbon 109-115 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 41-47 30360148-1 2019 To study the photocatalytic activity under visible light irradiation, a series of mesoporous graphitic carbon nitride (mpg-C3N4)/Ag2O photocatalysts were synthesized. Carbon 93-102 N-methylpurine DNA glycosylase Homo sapiens 119-122 32261236-1 2013 We present an X-ray absorption spectroscopy study of the local structure around the Gd3+ ions loaded within ultra-short carbon nanotubes (US-tubes). Carbon 120-126 GRDX Homo sapiens 84-87 30308895-8 2019 Further functional simulation of these bacterial herds unveiled the change of Ca2+ and available phosphorus might disturb the soil carbon and nitrogen metabolism, and thus weakened soil quality. Carbon 131-137 carbonic anhydrase 2 Homo sapiens 78-81 33124263-5 2020 (2) For soil organic carbon fractions, the decline rate of the content of soil inert organic carbon under the CK treatment increased with increasing temperature, and was sensitive to the changes in temperature. Carbon 21-27 cytidine/uridine monophosphate kinase 1 Homo sapiens 110-112 33124263-5 2020 (2) For soil organic carbon fractions, the decline rate of the content of soil inert organic carbon under the CK treatment increased with increasing temperature, and was sensitive to the changes in temperature. Carbon 93-99 cytidine/uridine monophosphate kinase 1 Homo sapiens 110-112 23530764-3 2013 RESULTS: Results indicate that hMSC differentiation can be enhanced by either culturing in electrically conductive, carbon nanotube-containing composite scaffolds without electrical stimulation in the presence of 5-azacytidine, or extrinsic electrical stimulation in nonconductive poly(epsilon-caprolactone) scaffolds without carbon nanotube and azacytidine. Carbon 116-122 musculin Homo sapiens 31-35 33104355-3 2020 The trans-carboamination around the internal alkyne was achieved by syn/anti-rotation of the Ni-carbenoid intermediate formed by C-N bond cleavage of the nickelacycle, and 3-alkenylated indoles were formed by C-N bond-forming reductive elimination. Carbon 129-130 synemin Homo sapiens 68-71 33104355-3 2020 The trans-carboamination around the internal alkyne was achieved by syn/anti-rotation of the Ni-carbenoid intermediate formed by C-N bond cleavage of the nickelacycle, and 3-alkenylated indoles were formed by C-N bond-forming reductive elimination. Carbon 209-210 synemin Homo sapiens 68-71 33104370-2 2020 The key features of the strategy include construction of the C16 quaternary carbon center by a highly diastereoselective Grignard reagent addition to N-tert-butanesulfinylimine, sequential site-selective amidation and N-alkylation to form the C and E rings, and [Ni(COD)2]-mediated Michael addition to close the D ring. Carbon 76-82 COD2 Homo sapiens 262-271 30308921-7 2019 The results showed that the exposure patterns of phthalates varied among the population groups with different water intakes, and the health risk was higher for people ingesting the boiled tap water than that of the groups consuming bottled water (purified water) and filtered water with filter cartridge containing activated carbon. Carbon 325-331 nuclear RNA export factor 1 Homo sapiens 188-191 30468954-2 2019 Spin-lattice relaxation rate (1/T1) of side chain carbon nuclei were remarkably high, because those nuclei possess higher degree of motional freedom. Carbon 50-56 spindlin 1 Homo sapiens 0-4 23834285-3 2013 Here, we use the IR absorptions of carbon-deuterium (C-D) bonds site-selectively incorporated throughout the N-terminal SH3 domain from the murine adapter protein Crk-II to characterize its different microenvironments with high spatial and temporal resolution. Carbon 35-41 v-crk avian sarcoma virus CT10 oncogene homolog Mus musculus 163-169 30606816-9 2019 MTHFR-C677T altered protein turnover and folate mediated 1-carbon metabolic fluxes in lymphoblasts with and without MTX. Carbon 59-65 methylenetetrahydrofolate reductase Homo sapiens 0-5 30567668-1 2019 In this work, carbon quantum dots (CQD) encapsulated in super small platinum nanocrystals core-shell architecture/nitrogen doped graphene hybrid nanocomposite (CQD@PDA@PtNCs-NGR) was design synthesized. Carbon 14-20 reticulon 4 receptor Homo sapiens 174-177 33085886-1 2020 Carbothermal hydrogen reduction (CHR) is a unique dry chemical process used to fabricate metals and carbides on carbon supports. Carbon 112-118 chromate resistance; sulfate transport Homo sapiens 33-36 32035229-3 2020 beta-Carotene 15,15"-dioxygenase (BCO1) catalyzes the oxidative cleavage of the central 15,15" carbon-carbon double of beta-carotene bond by addition of molecular oxygen. Carbon 95-108 beta-carotene oxygenase 1 Homo sapiens 34-38 23954753-3 2013 This trend in the addition pattern is observed for primary amine, carbon and sulfur nucleophiles, whereas secondary amines prefer an equatorial addition at C-2. Carbon 66-72 complement C2 Homo sapiens 156-159 32574847-7 2020 The enhanced H2O2 production performance could be ascribed to the formation of CF2 and CF3 on the surface of F-doped CNT, which rendered the potential for practical application of novel carbon catalyst for GDE. Carbon 186-192 ATPase H+ transporting accessory protein 1 Homo sapiens 79-82 30701083-11 2019 Due to its central function in sucrose cycling and sugar signaling, our findings suggest an important role of hexokinase-1 for carbon allocation to either shoot growth or assimilate export. Carbon 127-133 hexokinase 1 Arabidopsis thaliana 110-122 24024653-6 2013 In the complexes of (fluorinated benzene)( +), the lowest energy isomers are electrostatically bonded where HCN is perpendicular to the ring and its dipole points to a positively charged ring carbon. Carbon 192-198 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 108-111 30664738-4 2019 We show that stimulation with a CpG oligodeoxynucleotide, a Toll-like receptor 9 agonist, evokes changes in the central carbon metabolism of macrophages that enable antitumor activity, including engulfment of CD47+ cancer cells. Carbon 120-126 CD47 molecule Homo sapiens 209-213 24041852-7 2013 Additional fixation of carbon due to exclusion of ambient UV-B was channeled towards yield as there was a decrease in the level of UV-B absorbing substances and an increase in soluble proteins in all the four plant species. Carbon 23-29 uncharacterized protein LOC107958776 Gossypium hirsutum 58-62 30614708-1 2019 A method for the synthesis of enantiopure 1,5-substituted hydantoins was developed using a hypervalent iodine cyanation reagent (cyanobenziodoxolone, CBX) as a source of electrophilic carbon. Carbon 184-190 chromobox 1 Homo sapiens 150-153 33059844-3 2020 The deletion of smt3 led to significant growth defects on the minimal media with different carbon and nitrogen sources, an obvious reduction (45.7 %) in aerial conidiation during optimal cultivation, and increasing sensitivities to metal ions, oxidation, cell wall perturbation, and the fungicide carbendazim during conidial germination and/or colony growth. Carbon 91-97 SUMO family protein SMT3 Saccharomyces cerevisiae S288C 16-20 24041852-7 2013 Additional fixation of carbon due to exclusion of ambient UV-B was channeled towards yield as there was a decrease in the level of UV-B absorbing substances and an increase in soluble proteins in all the four plant species. Carbon 23-29 uncharacterized protein LOC107958776 Gossypium hirsutum 131-135 23483653-2 2013 The additional role of PTS(Ntr) as a regulatory link between nitrogen and carbon utilization in Escherichia coli is assumed to be closely related to molecular functions of IIA(Ntr) in potassium homeostasis. Carbon 74-80 colicin Ia immunity protein Escherichia coli 172-175 33175737-1 2020 This contribution reports on the observation of a strong light localization of Anderson type in 1D systems consisting of ship-shaped carbon nanotubes. Carbon 133-139 inositol polyphosphate-5-phosphatase D Homo sapiens 121-125 30216834-1 2019 A hierarchical carbon nanosheet-based networks (GPC) with controllable pore structure are developed for physical adsorption and chemical adsorption of CO2. Carbon 15-21 glycophorin C (Gerbich blood group) Homo sapiens 48-51 30886796-2 2019 Here, a sacrificial-counter-electrode method to synthesize a MoS x /carbon nanotubes/Pt catalyst (0.55 wt% Pt loading) is developed, which exhibits a low overpotential of 25 mV at a current density of 10 mA cm-2, a low Tafel slope of 27 mV dec-1, and excellent stability under acidic conditions. Carbon 68-74 MOS proto-oncogene, serine/threonine kinase Homo sapiens 61-64 25434188-2 2013 At the alcohols-affected inhibition of the cholinesterase hydrolytic activity, the determining role was played not the total number carbon atoms in the alcohol molecule, but by the "effective length" of the carbohydrate chain. Carbon 132-138 butyrylcholinesterase Homo sapiens 43-57 30543208-4 2019 However, recently transition-metal-catalyzed auxiliary assisted site-selective C-7 functionalization of indoles has emerged as an elegant synthetic tool for carbon-carbon and carbon-heteroatom bond formation to diversify the indoles. Carbon 157-163 complement C7 Homo sapiens 79-82 30543208-4 2019 However, recently transition-metal-catalyzed auxiliary assisted site-selective C-7 functionalization of indoles has emerged as an elegant synthetic tool for carbon-carbon and carbon-heteroatom bond formation to diversify the indoles. Carbon 164-170 complement C7 Homo sapiens 79-82 30543208-4 2019 However, recently transition-metal-catalyzed auxiliary assisted site-selective C-7 functionalization of indoles has emerged as an elegant synthetic tool for carbon-carbon and carbon-heteroatom bond formation to diversify the indoles. Carbon 164-170 complement C7 Homo sapiens 79-82 33109186-15 2020 Moreover, blockade of purinergic P2 receptors (P2Rs) signaling using P2R antagonist, suramin, suppressed polyI:C-mediated increases of cilia-driven flow and CBF, indicating that TLR3-mediated ciliary activation depended on released extracellular ATP and the autocrine ATP-P2R loop. Carbon 111-112 p2rs None 47-51 33110140-5 2020 In addition, the electrochemical sensing of the immobilised T1R2-Reb-A complex with zinc oxide nanoparticles (ZnONPs) and graphene oxide (GO) were assessed by testing the performance of multiwalled carbon nanotube (MWCNT) as an adsorbent experimentally. Carbon 198-204 taste 1 receptor member 2 Homo sapiens 60-64 33101760-4 2020 Here, we used C=C bond reduction of 2-methylmaleimide by the NADPH-dependent ene-reductase YqjM as a model reaction for light-dependent biotransformations. Carbon 14-15 2,4-dienoyl-CoA reductase 1 Homo sapiens 61-66 33101760-4 2020 Here, we used C=C bond reduction of 2-methylmaleimide by the NADPH-dependent ene-reductase YqjM as a model reaction for light-dependent biotransformations. Carbon 16-17 2,4-dienoyl-CoA reductase 1 Homo sapiens 61-66 30475574-3 2018 Here, high-energy-density molecules hosted in inverse opal-like porous carbon (IOC) nanocomposites demonstrate the mechanical stabilization and desensitization of RDX and HMX inside the carbon nanostructure using host-guest chemistry techniques. Carbon 71-77 radixin Homo sapiens 163-166 30475574-3 2018 Here, high-energy-density molecules hosted in inverse opal-like porous carbon (IOC) nanocomposites demonstrate the mechanical stabilization and desensitization of RDX and HMX inside the carbon nanostructure using host-guest chemistry techniques. Carbon 186-192 radixin Homo sapiens 163-166 23865980-1 2013 N-Heterocyclic Olefin (NHO) with high electronegativity at the terminal carbon atom was found to show a strong tendency for CO2 sequestration, affording a CO2 adduct (NHO-CO2). Carbon 72-78 complement C2 Homo sapiens 124-127 30108105-8 2018 Biochemical studies indicate that glutamine is the predominant carbon source for L-2-HG via the activity of malate dehydrogenase 2 (MDH2). Carbon 63-69 malate dehydrogenase 2 Homo sapiens 132-136 33059856-3 2020 Thereafter, PtDEN-labeled anti-ProGRP secondary antibody was launched for the detection of target analyte with a sandwich-type assay format on anti-ProGRP capture antibody-modified screen-printed carbon electrode. Carbon 196-202 gastrin releasing peptide Homo sapiens 31-37 33059856-3 2020 Thereafter, PtDEN-labeled anti-ProGRP secondary antibody was launched for the detection of target analyte with a sandwich-type assay format on anti-ProGRP capture antibody-modified screen-printed carbon electrode. Carbon 196-202 gastrin releasing peptide Homo sapiens 148-154 32989163-1 2020 The AlkB family of nonheme Fe(II)/2-oxoglutarate-dependent oxygenases are essential regulators of RNA epigenetics by serving as erasers of one-carbon marks on RNA with release of formaldehyde (FA). Carbon 143-149 alkB homolog 1, histone H2A dioxygenase Homo sapiens 4-8 23865980-1 2013 N-Heterocyclic Olefin (NHO) with high electronegativity at the terminal carbon atom was found to show a strong tendency for CO2 sequestration, affording a CO2 adduct (NHO-CO2). Carbon 72-78 complement C2 Homo sapiens 155-158 30412378-8 2018 The GOx-loaded microcapsules were immobilized on a variety of surfaces (here, inside a flow channel, on a carbon-coated sensor or a graphite rod) and glucose concentrations up to 10 mM could successfully be measured. Carbon 106-112 hydroxyacid oxidase 1 Homo sapiens 4-7 23865980-1 2013 N-Heterocyclic Olefin (NHO) with high electronegativity at the terminal carbon atom was found to show a strong tendency for CO2 sequestration, affording a CO2 adduct (NHO-CO2). Carbon 72-78 complement C2 Homo sapiens 155-158 23865980-2 2013 X-ray single crystal analysis revealed the bent geometry of the binding CO2 in the NHO-CO2 adducts with an O-C-O angle of 127.7-129.9 , dependent on the substitute groups of N-heterocyclic ring. Carbon 72-73 complement C2 Homo sapiens 87-90 31458297-1 2018 Mesoporous carbon spheres (MCS-750, MCS-800, MCS-850, MCS-900, and MCS-950) have been synthesized by a facile strategy with low temperature and rapid chemical vapor deposition technique. Carbon 11-17 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 27-30 23545069-1 2013 In this study the effect of different particle sizes of granular activated carbon (GAC) on the performance of a submerged membrane bioreactor (SMBR) was investigated. Carbon 75-81 glutaminase Homo sapiens 83-86 31458297-1 2018 Mesoporous carbon spheres (MCS-750, MCS-800, MCS-850, MCS-900, and MCS-950) have been synthesized by a facile strategy with low temperature and rapid chemical vapor deposition technique. Carbon 11-17 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 36-39 31458297-1 2018 Mesoporous carbon spheres (MCS-750, MCS-800, MCS-850, MCS-900, and MCS-950) have been synthesized by a facile strategy with low temperature and rapid chemical vapor deposition technique. Carbon 11-17 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 36-39 31458297-1 2018 Mesoporous carbon spheres (MCS-750, MCS-800, MCS-850, MCS-900, and MCS-950) have been synthesized by a facile strategy with low temperature and rapid chemical vapor deposition technique. Carbon 11-17 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 36-39 31458297-1 2018 Mesoporous carbon spheres (MCS-750, MCS-800, MCS-850, MCS-900, and MCS-950) have been synthesized by a facile strategy with low temperature and rapid chemical vapor deposition technique. Carbon 11-17 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 36-39 33320561-0 2020 N, S, and P-Co-doped Carbon Quantum Dots: Intrinsic Peroxidase Activity in a Wide pH Range and Its Antibacterial Applications. Carbon 21-27 AT695_RS02070 Staphylococcus aureus 52-62 32975930-10 2020 Only sustainable materials were used as a carbon source for the production of target polymers, which showed excellent compatibility with the practically most demanding constructing materials (a universal reusable hot-melt adhesive for copper, brass, Be-copper, Mn-bronze, zinc, aluminum, titanium, and glass). Carbon 42-48 alcohol dehydrogenase iron containing 1 Homo sapiens 213-216 24358744-12 2013 However, the level of serum IL-4 [(112.05 +/- 15.02) ng/L] in A group was significant decreased at the 6th week after the infection, compared with that in the C group [(102.82 +/- 27.46) ng/L] (P < 0.05). Carbon 159-160 interleukin 4 Mus musculus 28-32 32533225-1 2020 An amperometric L-ascorbic acid biosensor utilizing ascorbate oxidase (AOx) immobilized onto poly(L-aspartic acid) (P(L-Asp)) film was fabricated on carbon nanofiber (CNF) and nanodiamond particle (ND)-modified glassy carbon electrode (GCE). Carbon 149-155 acyl-CoA oxidase 1 Homo sapiens 52-69 32533225-1 2020 An amperometric L-ascorbic acid biosensor utilizing ascorbate oxidase (AOx) immobilized onto poly(L-aspartic acid) (P(L-Asp)) film was fabricated on carbon nanofiber (CNF) and nanodiamond particle (ND)-modified glassy carbon electrode (GCE). Carbon 149-155 acyl-CoA oxidase 1 Homo sapiens 71-74 32533225-1 2020 An amperometric L-ascorbic acid biosensor utilizing ascorbate oxidase (AOx) immobilized onto poly(L-aspartic acid) (P(L-Asp)) film was fabricated on carbon nanofiber (CNF) and nanodiamond particle (ND)-modified glassy carbon electrode (GCE). Carbon 218-224 acyl-CoA oxidase 1 Homo sapiens 52-69 30287383-7 2018 Fully electrochemical methodology was used to prepare a new transducer on a glassy carbon surface which provided a high surface area to immobilize a high amount of the anti-CA 125. Carbon 83-89 mucin 16, cell surface associated Homo sapiens 173-179 30351107-7 2018 It is observed that formation of a thiazolidine ring from NAC occurs primarily in four steps, which involve proton abstraction from the thiol (SH) group of NAC and subsequent formation of an S-C bond by a nucleophilic attack of the C-S group on the protonated C-O-H group in NAC. Carbon 60-61 X-linked Kx blood group Homo sapiens 156-159 30351107-7 2018 It is observed that formation of a thiazolidine ring from NAC occurs primarily in four steps, which involve proton abstraction from the thiol (SH) group of NAC and subsequent formation of an S-C bond by a nucleophilic attack of the C-S group on the protonated C-O-H group in NAC. Carbon 60-61 X-linked Kx blood group Homo sapiens 156-159 23413977-3 2013 We tested the hypothesis that two dominant grazing resistant bacterial taxa, the ac1 tribe of Actinobacteria (ac1) and filamentous bacteria from the LD2 lineage (Saprospiraceae), profit from such carbon sources during periods of intense HNF predation. Carbon 196-202 long intergenic non-protein coding RNA 1587 Homo sapiens 81-84 30199807-3 2018 Analytically, AOX is determined by three sequential steps: 1) concentration and separation of AOX from halides with activated carbon, 2) conversion of AOX into halides with pyrolysis, and 3) quantification of halides via microcoulometry or ion chromatography (IC). Carbon 126-132 acyl-CoA oxidase 1 Homo sapiens 14-17 32533225-1 2020 An amperometric L-ascorbic acid biosensor utilizing ascorbate oxidase (AOx) immobilized onto poly(L-aspartic acid) (P(L-Asp)) film was fabricated on carbon nanofiber (CNF) and nanodiamond particle (ND)-modified glassy carbon electrode (GCE). Carbon 218-224 acyl-CoA oxidase 1 Homo sapiens 71-74 32738418-4 2020 MATERIALS AND METHODS: The role of CYLD in PD-L1 expression was assessed by knockdown of CYLD in TET cells upon stimulation with interferon gamma (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha) or polyinosinic-polycytidylic acid (poly I:C). Carbon 35-36 CYLD lysine 63 deubiquitinase Homo sapiens 89-93 32829711-12 2020 CONCLUSIONS: Our study provides evidence that altered CX3CL1-CX3CR1 and/or CD200-CD200R pathways, emerging after prenatal immune challenge with LPS and Poly I:C, might be involved in the aetiology of schizophrenia. Carbon 0-1 C-X3-C motif chemokine receptor 1 Rattus norvegicus 61-67 23413977-3 2013 We tested the hypothesis that two dominant grazing resistant bacterial taxa, the ac1 tribe of Actinobacteria (ac1) and filamentous bacteria from the LD2 lineage (Saprospiraceae), profit from such carbon sources during periods of intense HNF predation. Carbon 196-202 long intergenic non-protein coding RNA 1587 Homo sapiens 110-113 32789285-0 2020 Cold acclimation has a differential effect on leaf vascular bundle structure and carbon export rates in natural Arabidopsis accessions originating from southern and northern Europe. Carbon 81-87 cold, circadian rhythm, and rna binding 2 Arabidopsis thaliana 0-4 30400227-0 2018 Highly Photoluminescent and Stable N-Doped Carbon Dots as Nanoprobes for Hg2+ Detection. Carbon 43-49 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 73-76 23824634-12 2013 C++ source code is available for download from http://www.sbg.bio.ic.ac.uk/phyre2/PD2/. Carbon 0-3 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 82-85 30192960-4 2018 Assays with recombinant SlCPT5 produced in Escherichia coli determined that the enzyme synthesizes polyprenols of approximately 50-55 carbons (Pren-10, Pren-11) in length and accommodates a variety of trans-prenyldiphosphate precursors as substrates. Carbon 134-141 dehydrodolichyl diphosphate synthase 2 Solanum lycopersicum 24-30 30411915-4 2018 We uncover three low energy carbon polymorphs (Pbam-32, P6/mmm, and I4[over ]3d) with new topologies, containing 32, 36, and 94 atoms in their primitive cells, respectively. Carbon 28-34 solute carrier family 10 member 2 Homo sapiens 47-51 23403377-1 2013 Positron emission tomography (PET) imaging of monoamine oxidases (MAO-A: [(11)C]harmine, [(11)C]clorgyline, and [(11)C]befloxatone; MAO-B: [(11)C]deprenyl-D2) has been actively pursued given clinical importance of MAOs in human neuropsychiatric disorders. Carbon 77-79 monoamine oxidase A Homo sapiens 66-71 30336611-5 2018 It was found that the polyethylene glycol/carbon foam with multi-walled carbon nanotubes (PEG/MCF) composite PCMs had a better shape-stable performance below the temperature of 250 C, and the thermal conductivity of the PEG/MCF composite PCMs reached as high as 1.535 W/(mK), which was obviously higher than that of polyethylene glycol/carbon foam with single-walled carbon nanotubes (PEG/SCF, 1.159 W/(mK)). Carbon 42-48 KIT ligand Homo sapiens 390-393 30009896-3 2018 The result of glucose detection application shows that the Pd3Ag-LBP/C glassy carbon electrode (GCE) exhibits good stability and sensitivity. Carbon 78-84 lipopolysaccharide binding protein Homo sapiens 65-68 30062480-7 2018 This enzyme cascade of two subsequent C-C bond formations (EDA aldolase and a ThDP-dependent carboligase, MenD) generates two new stereocenters. Carbon 38-39 EBP cholestenol delta-isomerase Homo sapiens 106-110 29873416-6 2018 Using cell-based studies, we also establish that EWS cells are dependent on glutamine for cell survival and that EWS-FLI1 positively regulates expression of the glutamine transporter, SLC1A5 and two enzymes involved in the one-carbon cycle, MTHFD2 and MTHFD1L. Carbon 227-233 Fli-1 proto-oncogene, ETS transcription factor Homo sapiens 117-121 29873416-6 2018 Using cell-based studies, we also establish that EWS cells are dependent on glutamine for cell survival and that EWS-FLI1 positively regulates expression of the glutamine transporter, SLC1A5 and two enzymes involved in the one-carbon cycle, MTHFD2 and MTHFD1L. Carbon 227-233 solute carrier family 1 member 5 Homo sapiens 184-190 29873416-6 2018 Using cell-based studies, we also establish that EWS cells are dependent on glutamine for cell survival and that EWS-FLI1 positively regulates expression of the glutamine transporter, SLC1A5 and two enzymes involved in the one-carbon cycle, MTHFD2 and MTHFD1L. Carbon 227-233 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 241-247 32660245-2 2020 For the three nitrenes 1b, 2b, and 3b, two conformers exhibiting syn and anti configurations between the C=C and C=O bonds with respect to the C-C bonds have been identified. Carbon 105-106 synemin Homo sapiens 65-68 32660245-2 2020 For the three nitrenes 1b, 2b, and 3b, two conformers exhibiting syn and anti configurations between the C=C and C=O bonds with respect to the C-C bonds have been identified. Carbon 107-108 synemin Homo sapiens 65-68 32660245-2 2020 For the three nitrenes 1b, 2b, and 3b, two conformers exhibiting syn and anti configurations between the C=C and C=O bonds with respect to the C-C bonds have been identified. Carbon 107-108 synemin Homo sapiens 65-68 32660245-2 2020 For the three nitrenes 1b, 2b, and 3b, two conformers exhibiting syn and anti configurations between the C=C and C=O bonds with respect to the C-C bonds have been identified. Carbon 107-108 synemin Homo sapiens 65-68 32660245-2 2020 For the three nitrenes 1b, 2b, and 3b, two conformers exhibiting syn and anti configurations between the C=C and C=O bonds with respect to the C-C bonds have been identified. Carbon 107-108 synemin Homo sapiens 65-68 32761263-1 2020 In this paper, we investigate the effects of spin-dependent electron and defect in the carbon-based molecular device. Carbon 87-93 spindlin 1 Homo sapiens 45-49 32761263-4 2020 The spin effect and switching symbiosis are shown in this carbon-based device. Carbon 58-64 spindlin 1 Homo sapiens 4-8 32748925-0 2020 Nitrogenous carbon dot decorated natural microcline: an ameliorative dual fluorometric probe for Fe3+ and Cr6+ detection. Carbon 12-18 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 106-109 32399882-3 2020 Furthermore, positive tourism shock, in the long run, ameliorates the environmental quality by reducing carbon emissions in Nepal and Sri Lanka, however, increases the carbon emissions in Bangladesh, India, and Pakistan. Carbon 168-174 sorcin Homo sapiens 134-137 32166540-8 2020 In the outpatient study, only F1 + 2 exhibited a significant and negative association with C-Xa (rS = - 0.315, p = 0.026), and 37% of the variance could be explained by C-Xa levels. Carbon 91-92 coagulation factor XII Homo sapiens 30-36 32722648-1 2020 Lubiprostone, a 20-carbon synthetic fatty acid used for the treatment of constipation, is thought to act through an action on Cl- channel ClC-2. Carbon 19-25 chloride channel, voltage-sensitive 2 Mus musculus 138-143 32712310-3 2020 Here, we collate research related to the fraction of sp3 carbon atoms (Fsp3), including related high-throughput screening (HTS) cases, structural modifications based on Fsp3, and strategies to improve it. Carbon 57-63 NIPA magnesium transporter 1 Homo sapiens 71-75 32608963-3 2020 In this study, we report a high-performance paper-based humidity sensor based on a rationally designed bilayer structure consisting of a nano-porous cellulose nanofiber/carbon nanotube (CNF/CNT) sensitive layer and a micro-porous paper substrate. Carbon 169-175 NPHS1 adhesion molecule, nephrin Homo sapiens 186-189 32733776-2 2020 These arcs are used to generate nanoparticles of Cu and Ni and one-dimensional nanorods of CuS, ZnF2, and NiF2 protected with fluorinated amorphous carbon. Carbon 148-154 zinc finger protein 335 Homo sapiens 106-110 32345674-8 2020 Mechanistically, silencing the carbon switch ACLY in esophageal adenocarcinoma cells shortened GPL chains, linking de novo lipogenesis to the phospholipidome. Carbon 31-37 ATP citrate lyase Homo sapiens 45-49 32694789-0 2020 Inosine is an alternative carbon source for CD8+-T-cell function under glucose restriction. Carbon 26-32 CD8a molecule Homo sapiens 44-47 32567227-2 2020 Herein, carbon nanofiber matrix anchored with MgZnO nanoparticles (MgZnO/CNF) is developed as a flexible triple-gradient host for long cycling LMAs. Carbon 8-14 NPHS1 adhesion molecule, nephrin Homo sapiens 73-76 32432474-11 2020 The alpha- and beta-carbon addition reactions generate 1,3- (RA1) and 1,2-diol (RB1) adduct-radicals, respectively. Carbon 20-26 RA1 Homo sapiens 61-64 32458917-6 2020 Analysis of reaction mixtures leading to the formation of the MBBP analogs [(MBBP)Ni(R2-1,3-diketonate)]X (X = ClO4: 5: R = CH3; 6: R = C(CH3)3; 7-ClO4: R = Ph; X = Cl: 7-Cl: R = Ph) using 1H NMR and ESI-MS revealed the presence of [(MBBP)2Ni](ClO4)2 (8). Carbon 111-112 splicing factor 1 Homo sapiens 62-66 32493940-3 2020 The highly-purified ODR-10 was stabilized in micelle structures, and it was immobilized on a carbon nanotube field-effect transistor to build a bioelectronic nose for the detection of diacetyl, a butter flavor substance, via the specific interaction between diacetyl and ODR-10. Carbon 93-99 Serpentine receptor class r-10 Caenorhabditis elegans 20-26 32330571-0 2020 Impact of the MTHFR C677T polymorphism on one-carbon metabolites: Evidence from a randomised trial of riboflavin supplementation. Carbon 46-52 methylenetetrahydrofolate reductase Homo sapiens 14-19 31868234-2 2020 Binding of the active vitamin D metabolite, 1,25-dihydroxy vitamin D3 (1,25(OH)2 D3 ) to the vitamin D receptor (VDR) induces conformational changes in its C-terminal domain enabling competency for interaction with physiologically relevant coactivators, including SRC-1. Carbon 156-157 vitamin D receptor Homo sapiens 93-111 31868234-2 2020 Binding of the active vitamin D metabolite, 1,25-dihydroxy vitamin D3 (1,25(OH)2 D3 ) to the vitamin D receptor (VDR) induces conformational changes in its C-terminal domain enabling competency for interaction with physiologically relevant coactivators, including SRC-1. Carbon 156-157 vitamin D receptor Homo sapiens 113-116 32064729-7 2020 beta-cell function, measured by C-peptide oDI was 3 fold higher in GCK-MODY compared to HNF-MODY, and 1.5 fold higher than non-MODY (p for both <0.05). Carbon 32-33 glucokinase Homo sapiens 67-70 32455939-6 2020 Finally, MCMV replication in WAT explants resulted in decreased IL-10 levels, opposite to the effect seen with poly(I:C). Carbon 10-11 interleukin 10 Homo sapiens 64-69 32307492-0 2020 Osteopromotive carbon dots promote bone regeneration through the PERK-eIF2alpha-ATF4 pathway. Carbon 15-21 eukaryotic translation initiation factor 2A Homo sapiens 70-79 32307492-0 2020 Osteopromotive carbon dots promote bone regeneration through the PERK-eIF2alpha-ATF4 pathway. Carbon 15-21 activating transcription factor 4 Homo sapiens 80-84 32334428-7 2020 Instead, the carbon-coated N, Br co-doped LiFe0.99 Nb0.01PO4 (NBC-LFNP) and pristine cathode exhibited discharge capacities in the range of 169-73 mA h g-1 and 136-65 mA h g-1 at different rates in the range of 0.2 C-20 C with 92% and 40% capacity retention for 500 cycles, respectively. Carbon 13-19 proline rich protein BstNI subfamily 3 Homo sapiens 152-166 31981388-4 2020 Here, we cloned the long isoform of rat Cav2.1 (Cav2.1(e47)) and identified a novel variant with a shorter C-terminus (Cav2.1(e47s)) that differs from those previously described in the rat and mouse. Carbon 40-41 calcium voltage-gated channel subunit alpha1 A Rattus norvegicus 48-59 31981388-4 2020 Here, we cloned the long isoform of rat Cav2.1 (Cav2.1(e47)) and identified a novel variant with a shorter C-terminus (Cav2.1(e47s)) that differs from those previously described in the rat and mouse. Carbon 40-41 calcium voltage-gated channel subunit alpha1 A Rattus norvegicus 48-54 31981388-6 2020 We show that Cav2.1 isoforms produced short (CT1) and long (CT1(e47)) C-terminal fragments that interacted in vivo with the auxiliary Cavbeta4a subunit. Carbon 13-14 cardiotrophin 1 Rattus norvegicus 45-48 31981388-6 2020 We show that Cav2.1 isoforms produced short (CT1) and long (CT1(e47)) C-terminal fragments that interacted in vivo with the auxiliary Cavbeta4a subunit. Carbon 13-14 cardiotrophin 1 Rattus norvegicus 60-63 31981388-8 2020 Furthermore, the functional properties of a Cav2.1 mutant without the C-terminal Cavbeta4 binding domain (Cav2.1DeltaCT2) were similar to those of Cav2.1, and were not influenced by the co-expression of the missing fragments (CT2 or CT2(e47)). Carbon 44-45 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog Xenopus laevis 106-112 32010959-5 2020 We identify a functional nuclear localization signal (NLS; 412-442aa) at the C-terminal region of GLP-1R. Carbon 77-78 glucagon-like peptide 1 receptor Rattus norvegicus 98-104 32017069-4 2020 A mass spectrometry analysis revealed that IkappaBbeta phosphorylation sites are distributed in its C-terminal region, whereas IkappaBalpha phosphorylation sites are located in the N-terminal region. Carbon 100-101 NFKB inhibitor beta Homo sapiens 43-54 31978918-0 2020 Spin current generation and control in carbon nanotubes by combining rotation and magnetic field. Carbon 39-45 spindlin 1 Homo sapiens 0-4 32073726-9 2020 This interaction was prevented by epsilon-aminocaproic acid or carboxypeptidase B treatment suggesting that plasminogen/DIP-plasmin binds to FIXagamma/FIXadelta through newly generated C-terminal Lys316 and Lys413. Carbon 185-186 carboxypeptidase B1 Homo sapiens 63-81 32278748-4 2020 Under such conditions, alternative oxidase provides an extra-chloroplastic means to optimize the status of chloroplast energy pools (ATP, NADPH) and to manage cellular carbohydrate pools in response to changing rates of carbon fixation and carbon demand for growth and maintenance. Carbon 220-226 2,4-dienoyl-CoA reductase 1 Homo sapiens 138-143 30386789-2 2018 Besides, Tps1 plays a key role in carbon and energy homeostasis in this microbial cell, as shown by the well documented loss of ATP and hyper accumulation of sugar phosphates in response to glucose addition in a mutant defective in this protein. Carbon 34-40 alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1 Saccharomyces cerevisiae S288C 9-13 30238603-3 2018 Herein, a carbon nanofiber-stabilized graphene aerogel film (G-CNF film), inspired by constructional engineering, is constructed. Carbon 10-16 NPHS1 adhesion molecule, nephrin Homo sapiens 63-66 30238603-6 2018 Importantly, the G-CNF film can keep high Li plating/stripping efficiency at nearly 99% for over 700 h with an areal capacity of 10 mA h cm-2 (the specific capacity up to 2588 mA h g-1 based on the total mass of carbon host and Li metal). Carbon 212-218 NPHS1 adhesion molecule, nephrin Homo sapiens 19-22 30198722-2 2018 This cycloisomerization/Prins-type tandem transformation enabled direct access to the atypical tricyclic carbon skeleton of the natural product with the required syn/ anti/ syn ring fusion. Carbon 105-111 synemin Homo sapiens 162-165 30198722-2 2018 This cycloisomerization/Prins-type tandem transformation enabled direct access to the atypical tricyclic carbon skeleton of the natural product with the required syn/ anti/ syn ring fusion. Carbon 105-111 synemin Homo sapiens 173-176 30091504-0 2018 Modular Functionalization of Arenes in a Triply Selective Sequence: Rapid C(sp2 ) and C(sp3 ) Coupling of C-Br, C-OTf, and C-Cl Bonds Enabled by a Single Palladium(I) Dimer. Carbon 74-75 carbonyl reductase 1 Homo sapiens 106-110 30091504-4 2018 This allowed the realization of the first general and triply selective sequential C-C coupling (in 2D and 3D space) of C-Br followed by C-OTf and then C-Cl bonds. Carbon 82-83 carbonyl reductase 1 Homo sapiens 119-123 30091504-4 2018 This allowed the realization of the first general and triply selective sequential C-C coupling (in 2D and 3D space) of C-Br followed by C-OTf and then C-Cl bonds. Carbon 84-85 carbonyl reductase 1 Homo sapiens 119-123 32060094-6 2020 Pol I mutants lacking either the heterodimeric subunit Rpa34.5/Rpa49 or the C-terminal part of the specific subunit Rpa12.2 showed a lower processivity on naked DNA templates, which was even more reduced in the presence of a nucleosome. Carbon 76-77 DNA-directed RNA polymerase I core subunit RPA12 Saccharomyces cerevisiae S288C 116-121 30091504-4 2018 This allowed the realization of the first general and triply selective sequential C-C coupling (in 2D and 3D space) of C-Br followed by C-OTf and then C-Cl bonds. Carbon 84-85 carbonyl reductase 1 Homo sapiens 119-123 23313881-3 2013 A 5"-amino-terminated aptamer is covalently attached onto MWCNTs/IL/Chit modified glassy carbon (GC) electrode via a linker of glutaraldehyde (GA). Carbon 89-95 chitinase 1 Homo sapiens 68-72 29887015-0 2018 Effect of carbon black functionalization on the analytical performance of a tyrosinase biosensor based on glassy carbon electrode modified with dihexadecylphosphate film. Carbon 10-16 tyrosinase Homo sapiens 76-86 29887015-0 2018 Effect of carbon black functionalization on the analytical performance of a tyrosinase biosensor based on glassy carbon electrode modified with dihexadecylphosphate film. Carbon 113-119 tyrosinase Homo sapiens 76-86 23313881-3 2013 A 5"-amino-terminated aptamer is covalently attached onto MWCNTs/IL/Chit modified glassy carbon (GC) electrode via a linker of glutaraldehyde (GA). Carbon 97-99 chitinase 1 Homo sapiens 68-72 23530942-3 2013 With increasing the OFA damper opening, both fluctuations in NOx emissions and carbon in fly ash were initially slightly over OFA damper openings of 0-40% but then lengthened dramatically in openings of 40-70% (i.e., NOx emissions reduced sharply accompanied by an apparent increase in carbon in fly ash). Carbon 286-292 NADPH oxidase Drosophila melanogaster 61-64 30082496-7 2018 The aap2 plants outperformed wild-type plants with respect to growth, seed yield and carbon storage pools, and nitrogen use efficiency in both high and deficient nitrogen environments. Carbon 85-91 amino acid permease 2 Arabidopsis thaliana 4-8 32100538-2 2020 A commercially available activated carbon felt has been found to effectively capture lead from tap water, and partnered with X-Ray fluorescence (XRF) spectrometry, it provides quantitative measurement of aqueous lead in drinking water. Carbon 35-41 nuclear RNA export factor 1 Homo sapiens 95-98 29788500-0 2018 Microvascular Dysfunction Following Multiwalled Carbon Nanotube Exposure Is Mediated by Thrombospondin-1 Receptor CD47. Carbon 48-54 CD47 molecule Homo sapiens 114-118 23530942-3 2013 With increasing the OFA damper opening, both fluctuations in NOx emissions and carbon in fly ash were initially slightly over OFA damper openings of 0-40% but then lengthened dramatically in openings of 40-70% (i.e., NOx emissions reduced sharply accompanied by an apparent increase in carbon in fly ash). Carbon 286-292 NADPH oxidase Drosophila melanogaster 217-220 32052951-0 2020 CEAP clinical classes C0S-C4: differences, similarities and place of Ruscus+HMC+VitC in treating patients with chronic venous disease. Carbon 22-28 biogenesis of lysosomal organelles complex 1 subunit 2 Homo sapiens 0-4 32052951-2 2020 Using the CEAP classification as a special theme, a symposium entitled "CEAP Clinical Classes C0S-C4: Differences, Similarities and Place of Ruscus+HMC+VitC in Treating Patients with CVD" was held at the annual meeting of the 2019 European Venous Forum. Carbon 94-100 biogenesis of lysosomal organelles complex 1 subunit 2 Homo sapiens 10-14 23530942-7 2013 By sharply opening the OFA damper to deepen the air-staging conditions, although NOx emissions could finally reduce to 503 mg/m(3) at 6% O2 (i.e., an ultralow NOx level for down-fired furnaces), carbon in fly ash jumped sharply to 15.10%. Carbon 195-201 NADPH oxidase Drosophila melanogaster 81-84 32052951-2 2020 Using the CEAP classification as a special theme, a symposium entitled "CEAP Clinical Classes C0S-C4: Differences, Similarities and Place of Ruscus+HMC+VitC in Treating Patients with CVD" was held at the annual meeting of the 2019 European Venous Forum. Carbon 94-100 biogenesis of lysosomal organelles complex 1 subunit 2 Homo sapiens 72-76 23229576-0 2013 Highly conductive carbon nanotube matrix accelerates developmental chloride extrusion in central nervous system neurons by increased expression of chloride transporter KCC2. Carbon 18-24 solute carrier family 12, member 5 Mus musculus 168-172 31838721-8 2020 The cleavage of NRG2 by ADAM10 or BACE2 generates a C-terminal fragment that serves as a substrate for gamma-secretase. Carbon 36-37 neuregulin 2 Mus musculus 16-20 31994962-7 2020 In vivo crosslinking data reveal that Sgd1 binds to helix H12 of the 18S rRNA sequence and we further demonstrate that this interaction is formed by the C-terminal region of the protein, which is essential for its function in ribosome biogenesis. Carbon 153-154 nucleolar protein with MIF4G domain 1 Homo sapiens 38-42 30074764-3 2018 The coordination among Fe3+, ellagic acid, and graphene oxide would drive the formation of a sandwichlike assembly, which was subsequently converted into graphene-supported Fe@graphitic carbon core-shell nanoparticles (denoted as GEF). Carbon 186-192 Rho/Rac guanine nucleotide exchange factor 2 Homo sapiens 230-233 30228815-1 2018 Background and Objective: Serine hydroxymethyltransferase 2 (SHMT2) functions as a key enzyme in serine/glycine biosynthesis and one-carbon metabolism. Carbon 133-139 serine hydroxymethyltransferase 2 Homo sapiens 26-59 30228815-1 2018 Background and Objective: Serine hydroxymethyltransferase 2 (SHMT2) functions as a key enzyme in serine/glycine biosynthesis and one-carbon metabolism. Carbon 133-139 serine hydroxymethyltransferase 2 Homo sapiens 61-66 23411433-3 2013 This rearrangement at C-3 carbon differs from the previously described epimerization at C-2 of aldoses catalyzed by Mo(VI) ions, known as Bilik reaction. Carbon 26-32 complement C2 Homo sapiens 88-91 29741497-5 2018 In this work, it is hypothesised that carbon nanotube-based composites all adhere to a RLC interior circuit. Carbon 38-44 integrin subunit alpha 9 Homo sapiens 87-90 29741497-10 2018 The RLC model provides a new route to detect the inductance and capacitance of carbon nanotubes. Carbon 79-85 integrin subunit alpha 9 Homo sapiens 4-7 32035259-0 2020 Facile Strategy by Hyaluronic Acid Functional Carbon Dot-Doxorubicin Nanoparticles for CD44 Targeted Drug Delivery and Enhanced Breast Cancer Therapy. Carbon 46-52 CD44 antigen Mus musculus 87-91 32035259-2 2020 CD44 targeted HA-modified carbon dots (HA-CDs) were synthesized as carrier by one-step hydrothermal treatment within one hour with citric acid and branch-PEI as core carbon source. Carbon 26-32 CD44 antigen Mus musculus 0-4 32035259-2 2020 CD44 targeted HA-modified carbon dots (HA-CDs) were synthesized as carrier by one-step hydrothermal treatment within one hour with citric acid and branch-PEI as core carbon source. Carbon 166-172 CD44 antigen Mus musculus 0-4 23548138-6 2013 BK2 and DK samples showed a high content of total carbon characteristic of urban areas. Carbon 50-56 bradykinin receptor B2 Homo sapiens 0-3 31872214-5 2020 A Populus GATA gene, PdGATA19/PdGNC (GATA nitrate-inducible carbon-metabolism-involved), was identified from a rapid-growing Populus clone. Carbon 60-66 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 10-14 29859749-0 2018 Corrigendum to "Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures" [Bioorg. Carbon 134-140 lysine demethylase 1A Homo sapiens 97-101 23357280-1 2013 We previously showed that knockdown of the anaplerotic enzyme pyruvate carboxylase in the INS-1 832/13 insulinoma cell line inhibited glucose-stimulated insulin release and glucose carbon incorporation into lipids. Carbon 181-187 insulin 1 Rattus norvegicus 90-95 29956699-1 2018 A highly sensitive interdigitated electrode (IDE) with vertically aligned dense carbon nanotube forests directly grown on conductive supports was demonstrated by combining UV lithography and a low temperature chemical vapor deposition process (470 C). Carbon 80-86 insulin degrading enzyme Homo sapiens 45-48 29927601-3 2018 The group separation energies are endothermic and the BDE increases with additional substitution as a result of the increase in charge at the central carbon. Carbon 150-156 homeobox D13 Homo sapiens 54-57 31872214-5 2020 A Populus GATA gene, PdGATA19/PdGNC (GATA nitrate-inducible carbon-metabolism-involved), was identified from a rapid-growing Populus clone. Carbon 60-66 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 23-27 31951312-4 2020 Here, a unique interaction between electron-rich substituents in the peri position and the silyl group located on the bridgehead sp3-carbon is discussed on the example of 1,4-dichloro-9-(p-methoxyphenyl)-silyltriptycene (TRPCl) which exists in solution in the form of two rotamers differing by dispositions, syn or anti, of the Si-CPh (the CPh atom is from the p-methoxyphenyl group) bond against the peri-Cl atom. Carbon 133-139 synemin Homo sapiens 309-312 23355467-4 2013 Fat body lipid profiling revealed changes in both carbon chain length and degree of unsaturation of fatty acid substituents, particularly in stored triglycerides. Carbon 50-56 fat Drosophila melanogaster 0-3 30960702-1 2018 In this study, conductive carbon nanofibers (CNFs) were dispersed into epoxy resin and then infused into glass fiber fabric to fabricate CNF/glass fiber-reinforced polymer (GFRP) laminates. Carbon 26-32 NPHS1 adhesion molecule, nephrin Homo sapiens 45-48 25427494-1 2013 An ionic liquid-TiO2 nanoparticle modified carbon paste electrode (IL-TiO2/CPE) was used as a fast and sensitive tool for the investigation of the electrochemical oxidation of benserazide using voltammetry. Carbon 43-49 carboxypeptidase E Homo sapiens 75-78 29627528-4 2018 We detected 11 single nucleotide polymorphisms (SNP) of 7 one-carbon metabolism pathway genes (including MTHFR, MTR, MTRR, ALDH1L1, GART, SHMT1 and CBS) in donor livers and analyzed their association with HBV reinfection after liver transplantation. Carbon 62-68 methylenetetrahydrofolate reductase Homo sapiens 105-110 29622564-1 2018 Insulin is the paramount anabolic hormone, promoting carbon energy deposition in the body. Carbon 53-59 insulin Canis lupus familiaris 0-7 31927091-1 2020 This study investigated the regeneration of phenol saturated activated carbon fiber (ACF) with a novel electro-peroxydisulfate (E-PDS) process. Carbon 71-77 solute carrier family 26 member 4 Homo sapiens 130-133 31927091-9 2020 Therefore, E-PDS process showed promise for further evaluation as a potentially viable approach for the regeneration of carbons saturated with organic pollutants. Carbon 120-127 solute carrier family 26 member 4 Homo sapiens 13-16 23280693-7 2013 High expression of ABCG2 was also observed in cells with high p63 expression and low (<0.7) N/C ratio; however, they were positive for Cx-43. Carbon 21-22 tumor protein p63 Homo sapiens 62-65 32076763-7 2020 The proportion of cytoplasm area occupied by carbon particles in airway macrophages was over fivefold higher in current CBPs compared to non-CBPs and was associated with CBMN endpoints in a dose-dependent manner. Carbon 45-51 sushi repeat containing protein X-linked 2 Homo sapiens 120-124 32076763-7 2020 The proportion of cytoplasm area occupied by carbon particles in airway macrophages was over fivefold higher in current CBPs compared to non-CBPs and was associated with CBMN endpoints in a dose-dependent manner. Carbon 45-51 sushi repeat containing protein X-linked 2 Homo sapiens 141-145 29728975-8 2018 During the non-heating period, the role of transportation, both land and marine, increased and may have been significant in creating higher concentrations of carbon compounds in PM1 and PM2.5. Carbon 158-164 transmembrane protein 11 Homo sapiens 178-181 23132252-3 2013 This study aims to model and optimize the carbon source of auto-induction medium to enhance G-CSF production using artificial neural networks coupled with genetic algorithm. Carbon 42-48 colony stimulating factor 3 Homo sapiens 92-97 29948658-2 2018 Invertase (INV) is a key enzyme of carbon metabolism in both source and sink tissues. Carbon 35-41 invertase 2 Zea mays 0-9 29948658-2 2018 Invertase (INV) is a key enzyme of carbon metabolism in both source and sink tissues. Carbon 35-41 invertase 2 Zea mays 11-14 31901812-0 2020 Single-step synthesis of polychromatic carbon quantum dots for macroscopic detection of Hg2. Carbon 39-45 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 88-91 31901812-2 2020 The detection of Hg2+ by two kinds of carbon dots was further explored. Carbon 38-44 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 17-20 23432919-0 2013 Single-wall carbon nanohorns inhibited activation of microglia induced by lipopolysaccharide through blocking of Sirt3. Carbon 12-18 sirtuin 3 Mus musculus 113-118 31558842-2 2020 All cases reported carried either truncating variants located throughout the gene, or missense changes principally located at the C-terminal end of the protein mostly resulting in haploinsufficiency of TLK2. Carbon 130-131 tousled like kinase 2 Homo sapiens 202-206 31968405-8 2020 Further xenograft assays revealed that the tumour burden in the nude mice injected with LyP-1-functionalized multi-walled carbon nanotubes/MBD1siRNA was significantly relieved. Carbon 122-128 methyl-CpG binding domain protein 1 Mus musculus 139-143 32255156-0 2018 FRET and PET paired dual mechanistic carbon dots approach for tyrosinase sensing. Carbon 37-43 tyrosinase Homo sapiens 62-72 30018733-4 2018 Five genes in one-carbon metabolism pathway including MTHFR 677, MTHFR 1298, MTR 2756, MTRR 66, and DHFR 19bp together with demographics, lifestyle, and dietary intake factors were examined in association with BC risks. Carbon 18-24 methylenetetrahydrofolate reductase Homo sapiens 54-59 30018733-4 2018 Five genes in one-carbon metabolism pathway including MTHFR 677, MTHFR 1298, MTR 2756, MTRR 66, and DHFR 19bp together with demographics, lifestyle, and dietary intake factors were examined in association with BC risks. Carbon 18-24 methylenetetrahydrofolate reductase Homo sapiens 65-70 29728380-6 2018 Structural feature analyses revealed 1-alkenes with three carbon chain lengths (C15, C17, and C19). Carbon 58-64 placenta associated 8 Homo sapiens 80-83 23312023-3 2013 The electrochemical performance of typical CoP and Co(2)P samples as anode materials has been investigated and the CoP hollow nanoparticle with carbon coating layer depicts good capacity retention and high rate capability (e.g., specific capacity of 630 mA h g(-1) at 0.2 C after 100 cycles, and a reversible capacity of 256 mA h g(-1) can be achieved at a high current rate of 5 C). Carbon 144-150 caspase recruitment domain family member 16 Homo sapiens 43-46 32027052-1 2020 An automated radiosynthesis of carbon-11 positron emission tomography radiotracer [11 C]UCB-J for imaging the synaptic density biomarker synaptic vesicle glycoprotein SV2A was established using Synthra RNPlus synthesizer. Carbon 31-37 synaptic vesicle glycoprotein 2A Homo sapiens 167-171 29914047-2 2018 The properties and structure of in situ transformed PAN-based carbon fibers are investigated by Nano indenter, SEM, TEM, XRD, and Raman. Carbon 62-68 MFT2 Homo sapiens 116-119 23312023-3 2013 The electrochemical performance of typical CoP and Co(2)P samples as anode materials has been investigated and the CoP hollow nanoparticle with carbon coating layer depicts good capacity retention and high rate capability (e.g., specific capacity of 630 mA h g(-1) at 0.2 C after 100 cycles, and a reversible capacity of 256 mA h g(-1) can be achieved at a high current rate of 5 C). Carbon 144-150 caspase recruitment domain family member 16 Homo sapiens 115-118 22898920-6 2013 Across seasons, forest birds primarily relied on C(3) carbon sources, whereas many farmland birds also assimilated C(4) carbon. Carbon 120-126 complement C4A (Rodgers blood group) Homo sapiens 115-119 29685969-2 2018 The compounds with linker lengths of 6 and 7 carbon atoms were the most potent in histone deacetylase (HDAC) inhibition, and were specific submicromolar inhibitors of the HDAC1, HDAC6 and HDAC8 isoforms. Carbon 45-51 histone deacetylase 9 Homo sapiens 82-101 29685969-2 2018 The compounds with linker lengths of 6 and 7 carbon atoms were the most potent in histone deacetylase (HDAC) inhibition, and were specific submicromolar inhibitors of the HDAC1, HDAC6 and HDAC8 isoforms. Carbon 45-51 histone deacetylase 9 Homo sapiens 103-107 29627893-4 2018 tPA monoclonal antibody was covalently attached onto single-wall carbon nanotubes (SWCNTs) using diimide-activated imidation coupling. Carbon 65-71 chromosome 20 open reading frame 181 Homo sapiens 0-3 29569779-13 2018 Furthermore, differential responses of cinv1 cinv2 seedlings to exogenous sugar supplementation support a function of CINVs in influencing carbon partitioning in Arabidopsis. Carbon 139-145 cytosolic invertase 2 Arabidopsis thaliana 45-50 31744771-3 2020 The accuracy of the calculated NMR chemical shift of the nominal but non-equivalent phenyl carbons C(3)/C(7) and C(4)/C(6) (ortho and meta to the acid -C(1)OOH group) of GA may not be evaluated using the experimental measurements at room temperature. Carbon 84-98 complement C3 Homo sapiens 99-103 31744771-5 2020 We further recognised that the C NMR chemical shifts of the nominal phenyl carbons (C(3)/C(7) and C(4)/C(6)) encode information for intramolecular hydrogen bonding network formed by GA conformers. Carbon 68-82 complement C3 Homo sapiens 84-88 31744771-5 2020 We further recognised that the C NMR chemical shifts of the nominal phenyl carbons (C(3)/C(7) and C(4)/C(6)) encode information for intramolecular hydrogen bonding network formed by GA conformers. Carbon 68-82 complement C7 Homo sapiens 89-93 22898920-7 2013 While C sources of frugivores and omnivores did not differ between forest and farmland communities, insectivores used more C(4) carbon in the farmland than in the forest. Carbon 128-134 complement C4A (Rodgers blood group) Homo sapiens 123-127 29412950-6 2018 A carboxyl functionalized multiwalled carbon nanotubes screen printed electrode was immobilized with papain (cysteine protease) where amino group of papain covalently bound carboxyl group on electrode surface by EDC (1-ethyl-3-(3-dimethylaminopropyl) carbodiimide) and NHS (N-hydroxysuccinimide) chemistry. Carbon 38-44 cathepsin B Homo sapiens 109-126 23218380-4 2013 The samples were treated by drying and wetting cycles prior to NMR analysis where the hornification phenomenon was recorded by spectral changes of the cellulose C-4 carbon signals. Carbon 165-171 complement C4A (Rodgers blood group) Homo sapiens 161-164 29762528-3 2018 Here, we report improved activated carbon (AC) electrodes (AC@G@NiF/G) simultaneously combining chemical vapor deposition (CVD) graphene-modified nickel foams (NiF/Gs) current collectors and high quality few-layer graphene conductive additive instead of carbon black (CB). Carbon 35-41 S100 calcium binding protein A9 Homo sapiens 64-67 29762528-3 2018 Here, we report improved activated carbon (AC) electrodes (AC@G@NiF/G) simultaneously combining chemical vapor deposition (CVD) graphene-modified nickel foams (NiF/Gs) current collectors and high quality few-layer graphene conductive additive instead of carbon black (CB). Carbon 35-41 S100 calcium binding protein A9 Homo sapiens 160-163 29501138-0 2018 An electrochemical immunosensor for cardiac Troponin I using electrospun carboxylated multi-walled carbon nanotube-whiskered nanofibres. Carbon 99-105 troponin I3, cardiac type Homo sapiens 36-54 32085439-15 2020 Consequently, SUMO3, ALC1, POLE4, PCBP4, MUTYH expression correlated with the higher RBE of carbon ions. Carbon 92-98 small ubiquitin like modifier 3 Homo sapiens 14-19 32085439-15 2020 Consequently, SUMO3, ALC1, POLE4, PCBP4, MUTYH expression correlated with the higher RBE of carbon ions. Carbon 92-98 mutY DNA glycosylase Homo sapiens 41-46 32069286-4 2020 We show that Mep2 variants lacking the C-terminal tail conserve the ability to induce filamentation, revealing that signaling can proceed in the absence of exclusive binding of putative partner to the largest cytosolic domain of the protein. Carbon 39-40 ammonium permease MEP2 Saccharomyces cerevisiae S288C 13-17 29501138-1 2018 A sandwich-type nanostructured immunosensor based on carboxylated multi-walled carbon nanotube (CMWCNT)-embedded whiskered nanofibres (WNFs) was developed for detection of cardiac Troponin I (cTnI). Carbon 79-85 troponin I3, cardiac type Homo sapiens 172-190 23597911-2 2013 The cysteic acid/PDDA-GN composite film was prepared by the electrochemical grafting of cysteic acid onto the PDDA-GN coated glassy carbon electrode (GCE). Carbon 132-138 aminomethyltransferase Homo sapiens 150-153 31843644-3 2020 SIRT7 contains a conserved catalytic core with long flanking N- and C-terminal extensions. Carbon 68-69 sirtuin 7 Homo sapiens 0-5 29475035-7 2018 Cyclic voltammetric measurements reveal that the direct electron transfer from the active center of GOx to the glassy carbon electrode facilitated upon its immobilization on the Ni-CysNSs film. Carbon 118-124 hydroxyacid oxidase 1 Homo sapiens 100-103 23099892-3 2013 Using the canonical Protein Kinase A (PKA) pathway as a test system, we show that changes in PKA activity can be measured in living cells as a modulation of the interaction between its regulatory (Bcy1) and catalytic (Tpk1 and Tpk2) subunits in response to changes in carbon metabolism, caffeine and methyl methanesulfonate (MMS) treatments and to modifications in the dosage of its enzymatic regulators, the phosphodiesterases. Carbon 268-274 cAMP-dependent protein kinase regulatory subunit BCY1 Saccharomyces cerevisiae S288C 197-201 29616556-2 2018 Herein, we demonstrate unique triaxial nanocables of conducting polypyrrole@SnS2@carbon nanofiber (PPy@SnS2@CNF) prepared via a facile combination of hydrothermal method and vapor-phase polymerization. Carbon 81-87 NPHS1 adhesion molecule, nephrin Homo sapiens 108-111 31883893-6 2020 Inhibition kinetics analyses showed that hypericin, pseudohypericin and I3,II8-biapigenin inhibited PL via a mixed manner, while molecular dynamics simulations revealed that three newly identified PL inhibitors could bind on PL at both the catalytic cavity and the interface between colipase and the C-terminal domain of PL. Carbon 300-301 pancreatic lipase Homo sapiens 197-199 31883893-6 2020 Inhibition kinetics analyses showed that hypericin, pseudohypericin and I3,II8-biapigenin inhibited PL via a mixed manner, while molecular dynamics simulations revealed that three newly identified PL inhibitors could bind on PL at both the catalytic cavity and the interface between colipase and the C-terminal domain of PL. Carbon 300-301 pancreatic lipase Homo sapiens 197-199 31883893-6 2020 Inhibition kinetics analyses showed that hypericin, pseudohypericin and I3,II8-biapigenin inhibited PL via a mixed manner, while molecular dynamics simulations revealed that three newly identified PL inhibitors could bind on PL at both the catalytic cavity and the interface between colipase and the C-terminal domain of PL. Carbon 300-301 pancreatic lipase Homo sapiens 197-199 29589612-2 2018 The MnS/MoS2/C hybrid delivers a high specific capacitance of 1162 F g-1 at 0.5 A g-1 in 2 M KOH electrolyte, and it possesses a good rate capacity with a retention of 75.7% (880 F g-1) at 10 A g-1, which is due to the synergetic effects of the components MnS, MoS2 and carbon matrix in the hybrid material. Carbon 270-276 glycophorin E (MNS blood group) Homo sapiens 4-7 29589612-3 2018 The carbon matrix in the hybrid material can not only anchor the active components of MnS and MoS2, but also transport electrons efficiently. Carbon 4-10 glycophorin E (MNS blood group) Homo sapiens 86-89 22750505-6 2013 S1P is irreversibly catabolized by S1P lyase (SPL), a highly conserved enzyme that catalyzes the cleavage of S1P at carbon bond C(2-3), resulting in formation of hexadecenal and ethanolamine-phosphate. Carbon 116-122 sphingosine-1-phosphate receptor 1 Mus musculus 0-3 29384499-0 2018 Carbon dots based immunosorbent assay for the determination of GFAP in human serum. Carbon 0-6 glial fibrillary acidic protein Homo sapiens 63-67 29394395-0 2018 Systems assessment of transcriptional regulation on central carbon metabolism by Cra and CRP. Carbon 60-66 catabolite gene activator protein Escherichia coli 89-92 29394395-1 2018 Two major transcriptional regulators of carbon metabolism in bacteria are Cra and CRP. Carbon 40-46 catabolite gene activator protein Escherichia coli 82-85 31960849-2 2020 We demonstrate that the encapsulation of lactate-oxidase (LOx) within a hydrophobic protective carbon-paste anode imparts unusually high stability during dynamically changing pH fluctuations and allows the BFC to continue harvesting the lactate bioenergy even after long exposures to acidic conditions. Carbon 95-101 lysyl oxidase Homo sapiens 41-56 31960849-2 2020 We demonstrate that the encapsulation of lactate-oxidase (LOx) within a hydrophobic protective carbon-paste anode imparts unusually high stability during dynamically changing pH fluctuations and allows the BFC to continue harvesting the lactate bioenergy even after long exposures to acidic conditions. Carbon 95-101 lysyl oxidase Homo sapiens 58-61 31932507-3 2020 GDE2 trafficking is directed by C-terminal tail sequences that determine GDE2"s ability to cleave GPI-anchored glypican-6 (GPC6) and induce a neuronal differentiation program. Carbon 32-33 glycerophosphodiester phosphodiesterase domain containing 5 Mus musculus 0-4 22750505-6 2013 S1P is irreversibly catabolized by S1P lyase (SPL), a highly conserved enzyme that catalyzes the cleavage of S1P at carbon bond C(2-3), resulting in formation of hexadecenal and ethanolamine-phosphate. Carbon 116-122 sphingosine-1-phosphate receptor 1 Mus musculus 35-38 31932507-3 2020 GDE2 trafficking is directed by C-terminal tail sequences that determine GDE2"s ability to cleave GPI-anchored glypican-6 (GPC6) and induce a neuronal differentiation program. Carbon 32-33 glycerophosphodiester phosphodiesterase domain containing 5 Mus musculus 73-77 31932507-5 2020 Moreover, we identify a C-terminal leucine residue in a unique motif that is essential for GDE2 internalization. Carbon 24-25 glycerophosphodiester phosphodiesterase domain containing 5 Mus musculus 91-95 29617334-1 2018 To reduce carbon emissions during production and realize the recycling of resources, the government has promulgated carbon cap-and-trade regulation and take-back regulation separately. Carbon 10-16 TNF receptor superfamily member 19 Homo sapiens 123-136 29617334-1 2018 To reduce carbon emissions during production and realize the recycling of resources, the government has promulgated carbon cap-and-trade regulation and take-back regulation separately. Carbon 116-122 TNF receptor superfamily member 19 Homo sapiens 123-136 22750505-6 2013 S1P is irreversibly catabolized by S1P lyase (SPL), a highly conserved enzyme that catalyzes the cleavage of S1P at carbon bond C(2-3), resulting in formation of hexadecenal and ethanolamine-phosphate. Carbon 116-122 sphingosine-1-phosphate receptor 1 Mus musculus 35-38 23036321-4 2013 Granular activated carbon was added as cathode to form macroscopic galvanic cells between Fe(0) and GAC and enhance the current efficiency of the Fe(0)/GAC micro-electrolysis system. Carbon 19-25 glutaminase Homo sapiens 100-103 29185200-1 2018 BACKGROUND: Methylenetetrahyfrofolate reductase (MTHFR) is the key enzyme for one carbon and folate metabolism. Carbon 82-88 methylenetetrahydrofolate reductase Homo sapiens 12-47 29185200-1 2018 BACKGROUND: Methylenetetrahyfrofolate reductase (MTHFR) is the key enzyme for one carbon and folate metabolism. Carbon 82-88 methylenetetrahydrofolate reductase Homo sapiens 49-54 31914411-2 2020 This activity is provided by the C-terminal helicase domain of viral nonstructural protein 3 (NS3). Carbon 33-34 KRAS proto-oncogene, GTPase Homo sapiens 94-97 31800296-5 2020 Bioinformatics and 3D-structure prediction indicate that, like most HSPs, chicken GRP75 has two principal domains (the N-terminal ATPase and C-terminal region). Carbon 141-142 heat shock protein family A (Hsp70) member 9 Gallus gallus 82-87 29578239-3 2018 Fats/oils are complex chemicals that are generally defined by carbon length and degree of unsaturation. Carbon 62-68 chromosome 10 open reading frame 90 Homo sapiens 0-4 23036321-4 2013 Granular activated carbon was added as cathode to form macroscopic galvanic cells between Fe(0) and GAC and enhance the current efficiency of the Fe(0)/GAC micro-electrolysis system. Carbon 19-25 glutaminase Homo sapiens 152-155 24096985-0 2013 Tip-enhanced nano-Raman analytical imaging of locally induced strain distribution in carbon nanotubes. Carbon 85-91 TOR signaling pathway regulator Homo sapiens 0-3 31933103-10 2020 Similar to 6-keto, 6alpha-OH and 6beta-OH significantly reduced the activity of the FASN gene promoter, which suggests that oxidation of carbon-6 in the B-ring may play an important role in the reduction of FASN expression. Carbon 137-143 fatty acid synthase Homo sapiens 84-88 31933103-10 2020 Similar to 6-keto, 6alpha-OH and 6beta-OH significantly reduced the activity of the FASN gene promoter, which suggests that oxidation of carbon-6 in the B-ring may play an important role in the reduction of FASN expression. Carbon 137-143 fatty acid synthase Homo sapiens 207-211 24096985-3 2013 Here we demonstrate colour-coded tip-enhanced Raman scattering imaging of strain distribution along the length of a carbon nanotube. Carbon 116-122 TOR signaling pathway regulator Homo sapiens 33-36 29432685-1 2018 Tetracyanomethane, C(CN)4, is a tetrahedral molecule containing a central sp3 carbon that is coordinated by reactive nitrile groups that could potentially transform to an extended CN network with a significant fraction of sp3 carbon. Carbon 78-84 cellular communication network factor 4 Homo sapiens 19-25 29432685-1 2018 Tetracyanomethane, C(CN)4, is a tetrahedral molecule containing a central sp3 carbon that is coordinated by reactive nitrile groups that could potentially transform to an extended CN network with a significant fraction of sp3 carbon. Carbon 226-232 cellular communication network factor 4 Homo sapiens 19-25 23577216-9 2013 In addition to inorganic N compounds that might play a key role in shaping the anammox microbiota, organic carbon, organic nitrogen, sulfate, sulfide and metals all showed the potentials to participate in the anammox process, releasing the strict dependence of the anammox bacteria upon the direct availability of inorganic N nutrients that might be limiting in certain areas of the Bohai Sea. Carbon 107-113 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 389-392 29245073-2 2018 In this paper, we reported that the synthesis of bismuth ferrite (BiFeO3) nanosheets integrated functionalized carbon nanofiber (BiFeO3 NS/F-CNF) nanocomposite using a simple hydrothermal technique. Carbon 111-117 NPHS1 adhesion molecule, nephrin Homo sapiens 141-144 31702436-7 2020 This suggests that the C-terminal PAD4 EP domain is necessary for EDS1-dependent immune functions. Carbon 23-24 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 34-38 31702436-7 2020 This suggests that the C-terminal PAD4 EP domain is necessary for EDS1-dependent immune functions. Carbon 23-24 alpha/beta-Hydrolases superfamily protein Arabidopsis thaliana 66-70 31926175-5 2020 Chronic liver injury was induced by intraperitoneal injection of carbon (CCl4), D-galactosamine (D-GalN) and thioacetamide (TAA), respectively. Carbon 65-71 chemokine (C-C motif) ligand 4 Mus musculus 73-77 31974343-2 2020 Here we report a sp2 carbon-conjugated fluorescent covalent organic framework (COF) named TFPT-BTAN-AO with excellent chemical, thermal and radiation stability is synthesized by integrating triazine-based building blocks with amidoxime-substituted linkers. Carbon 21-27 TCF3 fusion partner Homo sapiens 90-94 29564022-1 2018 Background: 5,10-Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in one-carbon metabolism that ensures the availability of methyl groups for methylation reactions. Carbon 84-90 methylenetetrahydrofolate reductase Homo sapiens 12-52 23234364-1 2012 We have developed a new catalyst supported on graphitized carbon black (GCB), which exhibits higher resistance to carbon corrosion than a conventional carbon black (CB), in order to favor both high mass activity for the oxygen reduction reaction (ORR) and high durability. Carbon 58-64 glucosylceramidase beta Homo sapiens 72-75 29564022-1 2018 Background: 5,10-Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in one-carbon metabolism that ensures the availability of methyl groups for methylation reactions. Carbon 84-90 methylenetetrahydrofolate reductase Homo sapiens 54-59 29387950-2 2018 In this paper, we described the application of "PANI/MWCNTs/Starch" modified carbon paste electrode (PCS-CPE) as a simple and highly sensitive cholesterol sensor. Carbon 77-83 carboxypeptidase E Bos taurus 105-108 22819948-5 2012 The feedback-resistant DAHP synthase encoded by aroG was achieved by replacing the residue Leu175 of aroG with Asp as to increase net carbon flow down the common pathway. Carbon 134-140 AroG Escherichia coli 48-52 29325861-10 2018 KATANA STML and Zpex Smile had a comparable zirconia-phase composition (60wt% c-ZrO2 phase). Carbon 33-34 transmembrane O-mannosyltransferase targeting cadherins 3 Homo sapiens 21-26 31866536-7 2020 In GAD1, SNPs rs3762556, rs3762555, rs3791878 and rs3749034 had strong linkage, and the frequency of the C-G-C-A haplotype was higher in the lower dose of methadone group. Carbon 105-110 glutamate decarboxylase 1 Homo sapiens 3-7 31894693-5 2020 The polymer blend exhibits a remarkably enhanced spin relaxation length (56 nm) and carrier mobility compared to pristine PBDTTT-C-T. From film microstructural characterizations, we propose that the enhanced spin/carrier transport properties are attributed to the formation of interlinked nanonetwork comprising of the PBDTTT-C-T chain bundles in the inert matrix to afford efficient intrachain charge conduction pathway. Carbon 122-130 spindlin 1 Homo sapiens 49-53 31894693-5 2020 The polymer blend exhibits a remarkably enhanced spin relaxation length (56 nm) and carrier mobility compared to pristine PBDTTT-C-T. From film microstructural characterizations, we propose that the enhanced spin/carrier transport properties are attributed to the formation of interlinked nanonetwork comprising of the PBDTTT-C-T chain bundles in the inert matrix to afford efficient intrachain charge conduction pathway. Carbon 122-130 spindlin 1 Homo sapiens 208-212 22819948-5 2012 The feedback-resistant DAHP synthase encoded by aroG was achieved by replacing the residue Leu175 of aroG with Asp as to increase net carbon flow down the common pathway. Carbon 134-140 AroG Escherichia coli 101-105 23090569-6 2012 The PB-FCNF modified glassy carbon electrode (PB-FCNF/GCE) shows good electrocatalysis toward the reduction of H(2)O(2), a product from the reduction of O(2) followed by glucose oxidase (GOD) catalysis of the oxidation of glucose to gluconic acid. Carbon 28-34 aminomethyltransferase Homo sapiens 46-57 31950357-0 2020 Microwave-assisted synthesis of carbon dots as reductant and stabilizer for silver nanoparticles with enhanced-peroxidase like activity for colorimetric determination of hydrogen peroxide and glucose. Carbon 32-38 peroxidase 24 Musa acuminata 111-121 29281767-3 2018 Here, we report niobium pentoxide/carbon/niobium carbide (MXene) hybrid materials (Nb2 O5 /C/Nb2 C) as photocatalysts for hydrogen evolution from water splitting. Carbon 34-40 contactin 5 Homo sapiens 83-86 22936617-2 2012 In the carbon-based fiber supercapacitor (FSC), which has high capacitance performance, commercial pen ink is directly utilized as the electrochemical material. Carbon 7-13 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 99-102 29876474-1 2018 The data shown in this article are based on the original research article entitled "An improved amperometric L-lactate biosensor based on covalent immobilization of microbial lactate oxidase onto carboxylated multiwalled carbon nanotubes/copper nanoparticles/ polyaniline modified pencil graphite electrode" (Dagar and Pundir, 2017) [1]. Carbon 221-227 lysyl oxidase Homo sapiens 175-190 29876474-2 2018 This article explains the fabrication of an amperometric L-lactate biosensor based on microbial lactate oxidase (LOx) covalent immobilization onto nanomatrix [(carboxylated multiwalled carbon nanotubes (cMWCNT)/copper nanoparticles (CuNPs)/polyaniline (PANI) hybrid film/pencil graphite electrode (PGE)]. Carbon 185-191 lysyl oxidase Homo sapiens 96-111 29876474-2 2018 This article explains the fabrication of an amperometric L-lactate biosensor based on microbial lactate oxidase (LOx) covalent immobilization onto nanomatrix [(carboxylated multiwalled carbon nanotubes (cMWCNT)/copper nanoparticles (CuNPs)/polyaniline (PANI) hybrid film/pencil graphite electrode (PGE)]. Carbon 185-191 lysyl oxidase Homo sapiens 113-116 29422671-3 2018 Here we show that phosphorylation of TRANSPARENT TESTA GLABRA1 (TTG1) is regulated by SHAGGY-like kinases 11/12 (SK11/12) and that this mediates carbon flow to fatty acid synthesis and seed coat traits in Arabidopsis seeds. Carbon 145-151 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 64-68 29422671-6 2018 Therefore, site-specific phosphorylation of TTG1 by SK11/SK12 regulates carbon partitioning between zygotic and maternal sinks in seeds. Carbon 72-78 Transducin/WD40 repeat-like superfamily protein Arabidopsis thaliana 44-48 31941999-2 2020 Here, we demonstrate that the ligand binding cavity in the sphingosine 1-phosphate receptor S1PR1, a class A GPCR, is in allosteric communication with both the beta-arrestin-binding C-terminal tail, and a receptor surface involved in oligomerization. Carbon 111-112 sphingosine-1-phosphate receptor 1 Homo sapiens 92-97 31952209-5 2020 The patients with advanced HCC (BCLC C) had significantly higher TIM-3 levels than patients with BCLC A (p = 0.009) and BCLC B (p = 0.019). Carbon 28-29 hepatitis A virus cellular receptor 2 Homo sapiens 65-70 23090989-7 2012 Toward the end of the carbon isotope excursion there is an increase in the delta(34)S values of CAS. Carbon 22-28 BCAR1 scaffold protein, Cas family member Homo sapiens 96-99 31585218-1 2020 Herein, strongly coupled Mo2C and Ni nanoparticles with in-situ formed interfaces encapsulated by porous carbon nanofibers (Ni-Mo2C-CNF) have been rationally fabricated via pyrolyzing electrospinning polyvinyl alcohol fibers containing hydrothermally obtained NiMoO4 under Ar atmosphere and applied as high-performance and stable electrocatalyst for HER in alkaline electrolytes. Carbon 105-111 NPHS1 adhesion molecule, nephrin Homo sapiens 132-135 22923057-6 2012 We found that wild-type and homologous recombination-deficient (Rad51D) cellular lethality was dependent on both the dose and LET of the carbon ions, whereas it was only dependent on dose for protons. Carbon 137-143 DNA repair protein RAD51 homolog 4 Cricetulus griseus 64-70 31825630-0 2020 AHNAK C-terminal peptide membrane binding - Interactions between the residues 5654-5673 of AHNAK and phospholipid monolayers and bilayers. Carbon 6-7 AHNAK nucleoprotein Homo sapiens 0-5 31825630-0 2020 AHNAK C-terminal peptide membrane binding - Interactions between the residues 5654-5673 of AHNAK and phospholipid monolayers and bilayers. Carbon 6-7 AHNAK nucleoprotein Homo sapiens 91-96 31825630-1 2020 The dysferlin membrane repair complex contains a small complex, S100A10-annexin A2, which initiates membrane repair by recruiting the protein AHNAK to the membrane, where it interacts via binding sites in the C-terminal region. Carbon 209-210 AHNAK nucleoprotein Homo sapiens 142-147 31825630-4 2020 An artificially synthesized peptide (pAHNAK), comprising the 20 amino acids in the C-terminal domain of AHNAK, was applied to Langmuir monolayer models, and the binding parameters and insertion angles were measured with surface tensiometry and ellipsometry. Carbon 83-84 AHNAK nucleoprotein Homo sapiens 38-43 31808491-1 2020 Electrochemical enantiorecognition of tyrosine (Tyr) isomers using a MOF@CCQDs/NiF electrode prepared by electrodepositing a metal-organic framework (MOF) and chiral carbon quantum dots (CCQDs) on Ni foil is reported. Carbon 166-172 S100 calcium binding protein A9 Homo sapiens 79-82 28512710-5 2018 This was particularly evident in the SC system because the higher hydrophobicity of BDE-99 determined the higher affinity and competition for sorption sites onto black carbon. Carbon 168-174 homeobox D13 Homo sapiens 84-87 29447794-10 2018 CONCLUSION: It is concluded that changes in C-level threshold and steady state of ECAP thresholds and significant changes in BDNF concentration could be regarded as an indicator of experienced-related plasticity after CI stimulation. Carbon 0-1 brain derived neurotrophic factor Homo sapiens 125-129 30023785-0 2018 Effect of Carbon Nanotubes on Direct Electron Transfer and Electrocatalytic Activity of Immobilized Glucose Oxidase. Carbon 10-16 hydroxyacid oxidase 1 Homo sapiens 100-115 29235696-4 2018 The reaction mechanism involves a weak adduct formation between 1 and Me3 SiCN leading to the activation of the Si-C bond, which subsequently undergoes sigma-bond metathesis with a C=O moiety. Carbon 76-77 malic enzyme 3 Homo sapiens 70-73 29235696-4 2018 The reaction mechanism involves a weak adduct formation between 1 and Me3 SiCN leading to the activation of the Si-C bond, which subsequently undergoes sigma-bond metathesis with a C=O moiety. Carbon 115-116 malic enzyme 3 Homo sapiens 70-73 22948445-3 2012 In 4-(hydroxymethyl)phenylboronic acid MIDA ester the inter-nuclear distance between the methyl carbon and boron was determined to be 2.76 +- 0.14 A, in agreement with the distance of 2.68 A determined by X-ray crystallography. Carbon 96-102 NADH:ubiquinone oxidoreductase complex assembly factor 7 Homo sapiens 39-43 29178775-2 2018 Here, we report a rational design of air cathode using a cobalt nitride (Co4N) functionalized carbon nanofiber (CNF) membrane as current collector-catalyst integrated air cathode. Carbon 94-100 NPHS1 adhesion molecule, nephrin Homo sapiens 112-115 31825428-0 2020 Formation of allylated quaternary carbon centers via C-O/C-O bond fragmentation of oxalates and allyl carbonates. Carbon 34-40 DAN domain BMP antagonist family member 5 Homo sapiens 53-60 31897753-0 2020 Multiwalled carbon nanotubes coated with cobalt(II) sulfide nanoparticles for electrochemical sensing of glucose via direct electron transfer to glucose oxidase. Carbon 12-18 hydroxyacid oxidase 1 Homo sapiens 145-160 31897753-1 2020 Multiwalled carbon nanotubes coated with cobalt(II) sulfide nanoparticles were prepared and used for immobilization of glucose oxidase (GOx) to obtain an electrochemical glucose biosensor. Carbon 12-18 hydroxyacid oxidase 1 Homo sapiens 119-134 22696309-1 2012 The proton accepting and donating abilities of cyclopropenylidene (c-C(3)H(2)) on its complexation with hydrogen halides H-X (X = F, Cl, Br) are analyzed using density-functional theory with three functionals (PBE0, B3LYP, and B3LYP-D) and benchmarked against second-order Moller-Plesset (MP2) theory. Carbon 12-13 tryptase pseudogene 1 Homo sapiens 289-292 31760439-5 2020 Of these constituents, Ca, C, Cl, S, and Fe had the highest concentrations: greater than 1 microg m-3. Carbon 23-24 general transcription factor IIE subunit 1 Homo sapiens 41-43 29271458-1 2018 Indium sulfide nanoparticle (NP)-embedded microporous carbons co-doped with S- and N-dopants are easily prepared by a direct carbonization of the as-prepared In(iii)-based metal-organic framework (In-MOF), [Et2NH2][In(tdc)2] DEF, containing ditopic S-containing 2,5-thiophenedicarboxylate (tdc2-) bridging linkers as a potential source of S-dopant. Carbon 54-61 UTP25 small subunit processome component Homo sapiens 225-228 22696309-4 2012 The MP2/aug-cc-pVTZ c-C(3)H(2) H-F complex potential energy surface turns out to be an asymmetric deep single well, while asymmetric double wells are found for the c-C(3)H(2) H-Cl and c-C(3)H(2) H-Br complexes, with an energy barrier of 4.1 kcal mol(-1) for proton transfer along the hydrogen bond in the latter complex. Carbon 12-13 tryptase pseudogene 1 Homo sapiens 4-7 22696309-4 2012 The MP2/aug-cc-pVTZ c-C(3)H(2) H-F complex potential energy surface turns out to be an asymmetric deep single well, while asymmetric double wells are found for the c-C(3)H(2) H-Cl and c-C(3)H(2) H-Br complexes, with an energy barrier of 4.1 kcal mol(-1) for proton transfer along the hydrogen bond in the latter complex. Carbon 13-14 tryptase pseudogene 1 Homo sapiens 4-7 22696309-4 2012 The MP2/aug-cc-pVTZ c-C(3)H(2) H-F complex potential energy surface turns out to be an asymmetric deep single well, while asymmetric double wells are found for the c-C(3)H(2) H-Cl and c-C(3)H(2) H-Br complexes, with an energy barrier of 4.1 kcal mol(-1) for proton transfer along the hydrogen bond in the latter complex. Carbon 22-23 tryptase pseudogene 1 Homo sapiens 4-7 33268656-3 2020 Extensive computational studies revealed that the driving force of the facile hydration of 9 is probably release of the ring strain of 9, which arises in part from the bent sp2-hybridized C3a carbon. Carbon 192-198 complement C3 Homo sapiens 188-191 22696309-4 2012 The MP2/aug-cc-pVTZ c-C(3)H(2) H-F complex potential energy surface turns out to be an asymmetric deep single well, while asymmetric double wells are found for the c-C(3)H(2) H-Cl and c-C(3)H(2) H-Br complexes, with an energy barrier of 4.1 kcal mol(-1) for proton transfer along the hydrogen bond in the latter complex. Carbon 13-14 tryptase pseudogene 1 Homo sapiens 4-7 29304828-0 2018 Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC. Carbon 83-89 ALK receptor tyrosine kinase Homo sapiens 98-101 29304828-0 2018 Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC. Carbon 83-89 EMAP like 4 Homo sapiens 102-106 22991924-6 2012 Terminal triols and tetraols respectively underwent cleavage of their C-2 and C-3 moieties to afford their corresponding two- and three-carbon-unit-shorter carboxylic acids. Carbon 136-142 complement C2 Homo sapiens 70-81 29304828-15 2018 In addition to conventional photon radiotherapy, ALK-inhibition also enhanced the effects of particle irradiation using carbon ions. Carbon 120-126 ALK receptor tyrosine kinase Homo sapiens 49-52 30758268-3 2020 This study aimed at investigating the relationship between the intakes of micronutrients involved in one-carbon metabolism with breast cancer (BrCa) and its subtype"s odds. Carbon 105-111 BRCA1 DNA repair associated Homo sapiens 143-147 31942195-3 2020 KEGG analysis results showed these DEGs were mainly enriched in cell cycle, oocyte meiosis, cellular senescence, carbon metabolism and p53 signaling pathway. Carbon 113-119 delta 4-desaturase, sphingolipid 1 Homo sapiens 35-39 30370192-8 2018 In addition, in the C-3102 group, there was a trend towards a decrease in the bone resorption marker tartrate-resistant acid phosphatase isoform 5b (TRACP-5b) when compared with the placebo group at 12 weeks of treatment (p=0.052). Carbon 20-21 acid phosphatase 5, tartrate resistant Homo sapiens 149-157 22836924-0 2012 Utilizing 3D SERS active volumes in aligned carbon nanotube scaffold substrates. Carbon 44-50 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 13-17 29259117-5 2017 The largest changes in expression plasticity were observed between fermentable (glucose or galactose) and nonfermentable (glycerol) carbon sources and were caused by mutations located in the RAP1 and GCR1 transcription factor binding sites. Carbon 132-138 DNA-binding transcription factor RAP1 Saccharomyces cerevisiae S288C 191-195 29072802-0 2017 Mesoporous Carbon@Titanium Nitride Hollow Spheres as an Efficient SeS2 Host for Advanced Li-SeS2 Batteries. Carbon 11-17 secernin 2 Homo sapiens 66-70 29072802-0 2017 Mesoporous Carbon@Titanium Nitride Hollow Spheres as an Efficient SeS2 Host for Advanced Li-SeS2 Batteries. Carbon 11-17 secernin 2 Homo sapiens 92-96 31896109-1 2020 OBJECTIVE: The purpose of this study was to investigate the clinical evolution of patients treated with carbon-coated stent, as well as its patency and the inflammatory response triggered by this process through the quantification of serum elements of the kallikrein-kinin system (KKS). Carbon 104-110 kallikrein related peptidase 4 Homo sapiens 256-266 29072802-3 2017 In this study, to exploit the advantages of SeS2 to the full and avoid its shortcomings, we designed and synthesized a hollow mesoporous carbon@titanium nitride (HMC@TiN) host for loading 70 wt % of SeS2 as a cathode material for Li-SeS2 batteries. Carbon 137-143 secernin 2 Homo sapiens 44-48 22742810-1 2012 A non-enzymatic glucose sensor of multi-walled carbon nanotube-ruthenium oxide/composite paste electrode (MWCNT-RuO(2)/CPE) was developed. Carbon 47-53 carboxypeptidase E Homo sapiens 119-122 29072802-3 2017 In this study, to exploit the advantages of SeS2 to the full and avoid its shortcomings, we designed and synthesized a hollow mesoporous carbon@titanium nitride (HMC@TiN) host for loading 70 wt % of SeS2 as a cathode material for Li-SeS2 batteries. Carbon 137-143 secernin 2 Homo sapiens 199-203 29072802-3 2017 In this study, to exploit the advantages of SeS2 to the full and avoid its shortcomings, we designed and synthesized a hollow mesoporous carbon@titanium nitride (HMC@TiN) host for loading 70 wt % of SeS2 as a cathode material for Li-SeS2 batteries. Carbon 137-143 secernin 2 Homo sapiens 199-203 29072802-4 2017 Benefiting from both physical and chemical entrapment by hollow mesoporous carbon and TiN, the HMC@TiN/SeS2 cathode manifests high utilization of the active material and excellent cycling stability. Carbon 75-81 secernin 2 Homo sapiens 103-107 31931988-1 2020 A simple method for molecular wiring of glucose oxidase (GOx) enzyme with a low cost Mn polypyridine complex, Mn(phen)2Cl2, carboxylic acid functionalized multiwalled carbon nanotube (f-MWCNT) and Nafion (Nf), which is useful for glucose oxidation and sensing application in pH 7 phosphate buffer solution, has been demonstrated. Carbon 167-173 hydroxyacid oxidase 1 Homo sapiens 40-55 31931988-1 2020 A simple method for molecular wiring of glucose oxidase (GOx) enzyme with a low cost Mn polypyridine complex, Mn(phen)2Cl2, carboxylic acid functionalized multiwalled carbon nanotube (f-MWCNT) and Nafion (Nf), which is useful for glucose oxidation and sensing application in pH 7 phosphate buffer solution, has been demonstrated. Carbon 167-173 hydroxyacid oxidase 1 Homo sapiens 57-60 31931988-2 2020 In the typical preparation, f-MWCNT, Mn(phen)2Cl2, Nafion and GOx solution/suspension were successfully drop-casted as layer-by-layer on a cleaned glassy carbon electrode and potential cycled using cylic voltametric (CV) technique. Carbon 154-160 hydroxyacid oxidase 1 Homo sapiens 62-65 28988820-4 2017 ATF4 upregulation by p62 deficiency in the stroma activates glucose carbon flux through a pyruvate carboxylase-asparagine synthase cascade that results in asparagine generation as a source of nitrogen for stroma and tumor epithelial proliferation. Carbon 68-74 activating transcription factor 4 Homo sapiens 0-4 33569544-6 2020 SHMT2 catalyzes the conversion of serine to glycine and produces an activated one-carbon unit that can be used to support S-adenosyl methionine synthesis. Carbon 82-88 serine hydroxymethyltransferase 2 Homo sapiens 0-5 22854090-0 2012 36 year trends in dissolved organic carbon export from Finnish rivers to the Baltic Sea. Carbon 36-42 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 84-87 32021158-6 2019 Results: The results show silver-doped ordered mesoporous carbons to positively condition cell viability, with a cell viability percentage >70% even for 10 wt% Ag, to modulate the expression of inflammatory cytokines and of genes involved in tissue repair (KRT6a, VEGFA, IVN) and remodeling (MMP9, TIMP3) in different cell systems. Carbon 58-65 matrix metallopeptidase 9 Homo sapiens 292-296 32021158-6 2019 Results: The results show silver-doped ordered mesoporous carbons to positively condition cell viability, with a cell viability percentage >70% even for 10 wt% Ag, to modulate the expression of inflammatory cytokines and of genes involved in tissue repair (KRT6a, VEGFA, IVN) and remodeling (MMP9, TIMP3) in different cell systems. Carbon 58-65 TIMP metallopeptidase inhibitor 3 Homo sapiens 298-303 28988820-4 2017 ATF4 upregulation by p62 deficiency in the stroma activates glucose carbon flux through a pyruvate carboxylase-asparagine synthase cascade that results in asparagine generation as a source of nitrogen for stroma and tumor epithelial proliferation. Carbon 68-74 nucleoporin 62 Homo sapiens 21-24 29126486-0 2017 Functionalized carbon quantum dots with dopamine for tyrosinase activity analysis. Carbon 15-21 tyrosinase Homo sapiens 53-63 29126486-3 2017 In this work, a facile fluorescent assay for TYR activity based on dopamine functionalized carbon quantum dots (CQDs-Dopa) has been developed. Carbon 91-97 tyrosinase Homo sapiens 45-48 22999886-6 2012 Induction of serine auxotrophy by PKM2 activation was accompanied by reduced carbon flow into the serine biosynthetic pathway and increased expression of high affinity serine transporters. Carbon 77-83 pyruvate kinase M1/2 Homo sapiens 34-38 28892705-5 2017 In addition, decreasing PH2 led to more carbon flow to carboxylic acids. Carbon 40-46 polyhomeotic homolog 2 Homo sapiens 24-27 31878192-6 2019 We demonstrated that the hRPB11balpha interacts with leucine b-Zip domain located on the C-terminal part of ATF4. Carbon 89-90 activating transcription factor 4 Homo sapiens 108-112 31703893-4 2019 According to our previous docking studies, SAR confirm that the hydrophobic nucleus (benzopyran-4-one or dihydrobenzopyran) is essential to activate PPARalpha and/or PPARgamma, and the flexible linker (side alkyl chain) should containg at least C5-carbon atoms to activate PPARgamma. Carbon 245-254 sarcosine dehydrogenase Homo sapiens 43-46 31920471-4 2019 Hereditary Ferritinopathy (HF) or neuroferritinopathy is an autosomal dominant neurodegenerative disease caused by mutations in the FTL C-terminal sequence, which in turn cause disorder and unraveling at the four-fold pores allowing iron leakage and enhanced formation of toxic, improperly coordinated iron (ICI). Carbon 136-137 ferritin light polypeptide 1 Mus musculus 132-135 22978798-11 2012 CONCLUSIONS: In this study we have discovered and characterised a mutation in MTH1 enabling Pdc- strains to grow on glucose as the sole carbon source. Carbon 136-142 Mth1p Saccharomyces cerevisiae S288C 78-82 28540421-5 2017 Env9 positively affects both formation of large LDs upon overexpression and LD proliferation under poor carbon source. Carbon 104-110 Env9p Saccharomyces cerevisiae S288C 0-4 29058829-0 2017 Large-Scale Fabrication of Core-Shell Structured C/SnO2 Hollow Spheres as Anode Materials with Improved Lithium Storage Performance. Carbon 27-28 strawberry notch homolog 2 Homo sapiens 51-54 29064233-0 2017 Micro-Intertexture Carbon-Free Iron Sulfides as Advanced High Tap Density Anodes for Rechargeable Batteries. Carbon 19-25 nuclear RNA export factor 1 Homo sapiens 62-65 29039674-0 2017 Spin-Charge Separation in Finite Length Metallic Carbon Nanotubes. Carbon 49-55 spindlin 1 Homo sapiens 0-4 30782400-11 2019 Our results also indicate that the examined active carbons from beech (KB), coconut shells (TE50), and hard coal (RB2) do not adsorb (or adsorb with very limited efficiency) the vitamins that are routinely added to feed, such as A, B1, D, and K. Broilers fed with feed mixtures supplemented with activated carbon (KB) resulted in increases in the weight of the chickens (~2%) after 14 days of application and 2% lower feed consumption (conversion) relative to a control sample. Carbon 51-58 RB transcriptional corepressor like 2 Homo sapiens 114-117 29039674-8 2017 Time evolution analysis of the charge and spin line densities evidences that the charge and spin density waves are elementary excitations of metallic carbon nanotubes. Carbon 150-156 spindlin 1 Homo sapiens 42-46 22814352-9 2012 In contrast, two-fold C/Si exchange in the weak retinoid agonist TTNN (7a) and 8a resulted in considerably different effects: a significant increase (7a 7b) and almost no change (8a 8b) in transcription activation potential for all three RAR isotypes. Carbon 22-23 retinoic acid receptor alpha Homo sapiens 238-241 29052671-3 2017 Next, we analyze the quantum nuclear motion of N D2 molecules (N < 4) confined in carbon nanotubes using a highly accurate adsorbate-wave-function-based approach, and compare it with the motion of molecular hydrogen. Carbon 85-91 mitochondrially encoded NADH dehydrogenase 2 Homo sapiens 47-51 28858767-3 2017 In the present study, 39 bisaryl-1,4-dien-3-one compounds with 5-carbon connection chains were designed and synthesized as MD2 inhibitors based on the analysis of the molecular docking of xanthohumol to MD2. Carbon 65-71 lymphocyte antigen 96 Homo sapiens 123-126 28525848-3 2017 Based on a novel signal amplification strategy the carbon dots (CDs) functionalized with aptamer (CD-aptamer) used as detection probe and PAMAM-Dendrimers/AuNPs was used for covalent attachment of CA125-antibody and completing the sandwich assay method. Carbon 51-57 mucin 16, cell surface associated Homo sapiens 197-202 28535471-4 2017 The carbonized PANI@GO hybrid was used to modify a glassy carbon electrode (GCE) based on GOx, resulting in efficient direct electron transfer (DET) and excellent bio-catalytic performance. Carbon 4-10 hydroxyacid oxidase 1 Homo sapiens 90-93 28970539-5 2017 The absolute configuration of C-11 in 1-4, which was difficult to be determined by common means due to the high conformational flexibility of the eight-carbon aliphatic chain attached at C-4, was determined by VCD method, suggesting a new horizon to define the absolute configurations of natural products possessing chains. Carbon 152-158 aldo-keto reductase family 1 member C4 Homo sapiens 30-34 28635185-2 2017 This study shows that SnO2 triple-shelled hollow superstructures (TSHSs) with a low carbon content (4.83%) constructed by layer-by-layer assembly of various nanostructure units can withstand a huge volume expansion of 231.8% and deliver a high reversible capacity of 1099 mAh g-1 even after 1450 cycles. Carbon 84-90 strawberry notch homolog 2 Homo sapiens 22-25 28387046-4 2017 The boronate esters Ar-B(OR)2 of pinacol, neopentylglycol, and ethyleneglycol react with cAAC at RT via reversible B-C oxidative addition to the carbene carbon atom to afford cAACMe (B{OR}2 )(Ar) (BCA1-BCA6). Carbon 153-159 C-X-C motif chemokine ligand 13 Homo sapiens 197-201 29201620-4 2017 By integrating the catalytically active CoFe2O4 nanoparticles with the N-doped carbon nanofibers, the as-synthesized CoFe2O4@N-CNF nanohybrid manifests superior OER performance with a low overpotential, a large current density, a small Tafel slope, and long-term durability in alkaline solution, outperforming the single component counterparts (pure CoFe2O4 and N-doped carbon nanofibers) and the commercial RuO2 catalyst. Carbon 79-85 NPHS1 adhesion molecule, nephrin Homo sapiens 127-130 29201620-4 2017 By integrating the catalytically active CoFe2O4 nanoparticles with the N-doped carbon nanofibers, the as-synthesized CoFe2O4@N-CNF nanohybrid manifests superior OER performance with a low overpotential, a large current density, a small Tafel slope, and long-term durability in alkaline solution, outperforming the single component counterparts (pure CoFe2O4 and N-doped carbon nanofibers) and the commercial RuO2 catalyst. Carbon 370-376 NPHS1 adhesion molecule, nephrin Homo sapiens 127-130 28303410-13 2017 DAU-C, but not DAU-A rats had a 35% mortality rate and exhibited a significantly increased gp91phox expression (DAU-C: 197 +- 33 versus CON-C: 100 +- 11; P < 0.05). Carbon 4-5 cytochrome b-245 beta chain Rattus norvegicus 91-99 28871711-8 2017 CONCLUSION: Although further studies are needed, our data suggest an important role of the MTHFR gene variants in the fine-tuning regulation of one-carbon metabolism in the brain. Carbon 148-154 methylenetetrahydrofolate reductase Homo sapiens 91-96 28326635-4 2017 The design features the introduction of a four-carbon-atom linker into the peptide epitope found in many TLE1 binding partners. Carbon 47-53 TLE family member 1, transcriptional corepressor Homo sapiens 105-109 30806950-4 2019 Traffic-related air pollutants or TRAP refers to a broad group of pollutants including elemental carbon, black soot, nitrogen dioxide (NO2), nitric oxide (NO), sulfur dioxide (SO2), particulate matter (PM2.5 and PM10), carbon monoxide (CO), and carbon dioxide (CO2). Carbon 97-103 TRAP Homo sapiens 34-38 30529640-1 2019 Here, we report the genomic features and the bioremediation potential of Halomonas desertis G11, a new halophilic species which uses crude oil as a carbon and energy source and displays intrinsic resistance to salt stress conditions (optimum growth at 10% NaCl). Carbon 148-154 serine/threonine kinase 19 Homo sapiens 92-95 31698189-3 2019 Here, we describe the generation of an iPSC line from a patient mutated in the polar amino acid-rich domain of PQBP1 resulting in a C-terminal truncated protein (c.459_462 delAGAG, type p.R153fs193X). Carbon 42-43 polyglutamine binding protein 1 Homo sapiens 111-116 31756921-3 2019 Four major classes of enzymes that attenuate TCR signaling include E3 ubiquitin kinases such as the Casitas B-lineage lymphoma proteins (Cbl-b and c-Cbl), and Itchy (Itch), inhibitory tyrosine phosphatases, such as Src homology region 2 domain-containing phosphatases (SHP-1 and SHP-2), inhibitory protein kinases, such as C-terminal Src kinase (Csk), and inhibitory lipid kinases such as Src homology 2 (SH2) domain-containing inositol polyphosphate 5-phosphatase (SHIP) and Diacylglycerol kinases (DGKs). Carbon 46-47 protein tyrosine phosphatase non-receptor type 11 Homo sapiens 279-284 31756921-3 2019 Four major classes of enzymes that attenuate TCR signaling include E3 ubiquitin kinases such as the Casitas B-lineage lymphoma proteins (Cbl-b and c-Cbl), and Itchy (Itch), inhibitory tyrosine phosphatases, such as Src homology region 2 domain-containing phosphatases (SHP-1 and SHP-2), inhibitory protein kinases, such as C-terminal Src kinase (Csk), and inhibitory lipid kinases such as Src homology 2 (SH2) domain-containing inositol polyphosphate 5-phosphatase (SHIP) and Diacylglycerol kinases (DGKs). Carbon 46-47 protein tyrosine phosphatase non-receptor type 6 Homo sapiens 269-274 31756921-3 2019 Four major classes of enzymes that attenuate TCR signaling include E3 ubiquitin kinases such as the Casitas B-lineage lymphoma proteins (Cbl-b and c-Cbl), and Itchy (Itch), inhibitory tyrosine phosphatases, such as Src homology region 2 domain-containing phosphatases (SHP-1 and SHP-2), inhibitory protein kinases, such as C-terminal Src kinase (Csk), and inhibitory lipid kinases such as Src homology 2 (SH2) domain-containing inositol polyphosphate 5-phosphatase (SHIP) and Diacylglycerol kinases (DGKs). Carbon 46-47 inositol polyphosphate-5-phosphatase D Homo sapiens 466-470 31260993-5 2019 The as-synthesized MWCNT-Inulin-TiO2 bio-nanocomposite immobilized with glucose oxidase (GOx) was incorporated into the carbon paste matrix and was utilized for the sensing of glucose in food products. Carbon 120-126 hydroxyacid oxidase 1 Homo sapiens 72-87 31260993-5 2019 The as-synthesized MWCNT-Inulin-TiO2 bio-nanocomposite immobilized with glucose oxidase (GOx) was incorporated into the carbon paste matrix and was utilized for the sensing of glucose in food products. Carbon 120-126 hydroxyacid oxidase 1 Homo sapiens 89-92 31803740-2 2019 Here, we identify that the canonical Wnt is presumably acylated by palmitic acid, a saturated 16-carbon fatty acid, at a conserved serine residue. Carbon 94-114 wingless-type MMTV integration site family, member 3 Danio rerio 37-40 31726976-3 2019 The tips of the Olfm1 "V" each consist of two C-terminal beta-propeller domains that enclose a calcium binding site. Carbon 46-47 olfactomedin 1 Homo sapiens 16-21 31624123-7 2019 Moreover, introduction of isoleucine mutations in the C-terminal heptad repeat to induce an extended MPER alpha-helical bundle structure yielded an antigenicity profile of cell surface-arrayed Env variants inconsistent with that found in the native prefusion state. Carbon 54-55 endogenous retrovirus group K member 20 Homo sapiens 193-196 31690790-1 2019 In a previous study, we proposed that age-related mitochondrial respiration defects observed in elderly subjects are partially due to age-associated downregulation of nuclear-encoded genes, including serine hydroxymethyltransferase 2 (SHMT2), which is involved in mitochondrial one-carbon (1C) metabolism. Carbon 282-288 serine hydroxymethyltransferase 2 (mitochondrial) Mus musculus 200-233 31690790-1 2019 In a previous study, we proposed that age-related mitochondrial respiration defects observed in elderly subjects are partially due to age-associated downregulation of nuclear-encoded genes, including serine hydroxymethyltransferase 2 (SHMT2), which is involved in mitochondrial one-carbon (1C) metabolism. Carbon 282-288 serine hydroxymethyltransferase 2 (mitochondrial) Mus musculus 235-240 31689955-9 2019 Here, we show that the absence of Asc1 resulted in massive exposure and accessibility of the C-terminal tail of its ribosomal neighbor Rps3 (uS3). Carbon 93-94 guanine nucleotide-binding protein subunit beta Saccharomyces cerevisiae S288C 34-38 31332417-5 2019 For twelve perfluoroalkyl carboxylic acids (PFCAs), an inverted U-shaped relationship existed between the PPARbeta/delta binding potency and the carbon chain length, with perfluorododecanoc acid (C12) showing the highest binding potency. Carbon 145-151 peroxisome proliferator activated receptor delta Homo sapiens 106-114 31673848-0 2019 Simultaneous determination of paracetamol and p-aminophenol using glassy carbon electrode modified with nitrogen- and sulfur- co-doped carbon dots. Carbon 73-79 poly(A) polymerase alpha Homo sapiens 46-59 31673848-0 2019 Simultaneous determination of paracetamol and p-aminophenol using glassy carbon electrode modified with nitrogen- and sulfur- co-doped carbon dots. Carbon 135-141 poly(A) polymerase alpha Homo sapiens 46-59 31673848-10 2019 Graphical abstract Schematic representation of a novel electrochemical sensor based on N, S co-doped walnut shell carbon modified glassy carbon electrode for determination of paracetamol and p-aminophenol. Carbon 114-120 poly(A) polymerase alpha Homo sapiens 191-204 31673848-10 2019 Graphical abstract Schematic representation of a novel electrochemical sensor based on N, S co-doped walnut shell carbon modified glassy carbon electrode for determination of paracetamol and p-aminophenol. Carbon 137-143 poly(A) polymerase alpha Homo sapiens 191-204 31281983-0 2019 Effects of Electronic Structure of Adjacent Carbon on the Strength of C F H F Organofluorine Hydrogen Bonds. Carbon 44-50 complement factor H Homo sapiens 70-75 31281983-1 2019 We investigate the effects of the electronic structure of carbon atom on the organofluorine hydrogen bonds, C F H F. Our results show that we can modulate the strength of organofluorine hydrogen bonds by adjusting the volume of fluorine atom in C F via changing the electronic structure of adjacent carbon atoms. Carbon 58-64 complement factor H Homo sapiens 108-113 31281983-1 2019 We investigate the effects of the electronic structure of carbon atom on the organofluorine hydrogen bonds, C F H F. Our results show that we can modulate the strength of organofluorine hydrogen bonds by adjusting the volume of fluorine atom in C F via changing the electronic structure of adjacent carbon atoms. Carbon 299-305 complement factor H Homo sapiens 108-113 31281983-2 2019 Different with the conventional hydrogen bonds, we found that instead of carbon rehybridization and hyperconjugative effects, the magnitude of fluorine atomic volume plays important roles in determining the strength of the C F H F organofluorine hydrogen bonds. Carbon 73-79 complement factor H Homo sapiens 223-228 31281983-3 2019 The lone pair electrons at both the proximal and the vicinal carbon dramatically reinforce the strength of C F H F organofluorine hydrogen bond with its interaction energy in the range of about 15-25 kcal/mol, that is, the carbanion-mediated organofluorine hydrogen bond could be very strong. Carbon 61-67 complement factor H Homo sapiens 107-112 31584597-3 2019 Furthermore, beta-CDHN also exhibited fast adsorption kinetics towards these pollutants with adsorption rate constants 6 to 200 times higher than those of activated carbon and other beta-CD-based adsorbents, meaning the former can remove these pollutants at a much faster adsorption rate than the latter adsorbents. Carbon 165-171 cadherin 2 Homo sapiens 18-22 31844685-6 2019 The presence of the C-terminal regions of SIX3 and SIX6 proteins, but not their SIX domains or homeodomains as previously thought, were required for interaction with GEMININ. Carbon 20-21 SIX homeobox 6 Homo sapiens 51-55 31844685-7 2019 Interestingly, the disordered C- and N- terminal regions of GEMININ were involved in binding to SIX3/SIX6. Carbon 30-31 SIX homeobox 6 Homo sapiens 101-105 31624245-3 2019 Integrating anti-MYCN ChIP-seq and gene expression profiles of neuroblastoma patients revealed the metabolic enzymes, MTHFD2 and PAICS, required for one-carbon metabolism and purine biosynthesis were concomitantly upregulated, which were more susceptible to metastatic neuroblastoma. Carbon 153-159 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 118-124 31681872-4 2019 To increase the iron loading and the number of iron-centered catalytically active sites, we selected three iron salts Fe(OAc)2, Fe(OTf)2, and Fe(BF4)2 6H2O, which show greatly enhanced solubility in the liquid carbon precursor (furfurylamine) compared to FeCl3 6H2O. Carbon 210-216 POU class 2 homeobox 2 Homo sapiens 128-136 31520592-1 2019 In view of previous crystallographic studies, N4-hydroxy-dCMP, a slow-binding thymidylate synthase inhibitor apparently caused "uncoupling" of the two thymidylate synthase-catalyzed reactions, including the N5,10-methylenetetrahydrofolate one-carbon group transfer and reduction, suggesting the enzyme"s capacity to use tetrahydrofolate as a cofactor reducing the pyrimidine ring C(5) in the absence of the 5-methylene group. Carbon 243-249 thymidylate synthase Mus musculus 78-98 31520592-1 2019 In view of previous crystallographic studies, N4-hydroxy-dCMP, a slow-binding thymidylate synthase inhibitor apparently caused "uncoupling" of the two thymidylate synthase-catalyzed reactions, including the N5,10-methylenetetrahydrofolate one-carbon group transfer and reduction, suggesting the enzyme"s capacity to use tetrahydrofolate as a cofactor reducing the pyrimidine ring C(5) in the absence of the 5-methylene group. Carbon 243-249 thymidylate synthase Mus musculus 151-171 31532667-0 2019 One-Step Facile Synthesis of Nitrogen-Doped Carbon Dots: A Ratiometric Fluorescent Probe for Evaluation of Acetylcholinesterase Activity and Detection of Organophosphorus Pesticides in Tap Water and Food. Carbon 44-50 nuclear RNA export factor 1 Homo sapiens 185-188 31553620-2 2019 While many congeners have been isolated with various oxidation and sulfation patterns, only two members of this family have been isolated bearing a carbon-carbon bond at C11, namely 11-saxitoxinethanoic acid and zetekitoxin AB. Carbon 148-161 RNA polymerase III subunit K Homo sapiens 170-173 31553620-3 2019 Herein we described a synthetic platform capable of efficiently targeting (+)-saxitoxin and 11-saxitoxinethanoic acid with an embedded C11 carbon-carbon bond. Carbon 139-152 RNA polymerase III subunit K Homo sapiens 135-138 31908739-5 2019 Methods: In this research, a model of acute liver failure was created in male and female immunocompetent Balb-C mice through intraperitoneal injection of Carbon tetrachlo-ride (CCl4 ) and MenSCs were transplanted intravenously 48 hrs after induction of liver injury to evaluate their therapeutic potential. Carbon 154-175 chemokine (C-C motif) ligand 4 Mus musculus 177-181 31452367-6 2019 The cord/maternal concentration fraction ratios (RCM) of CPs exhibited similar values from C10 to C14, and then from C15, a decreasing trend was observed with increasing carbon chain length. Carbon 170-176 placenta associated 8 Homo sapiens 117-120 31446906-9 2019 Proteomic analysis revealed that two candidate proteins were obtained in the hippocampus of polyI:C-treated mice, including aldehyde dehydrogenase family 1 member L1 (ALDH1L1) and collapsin response mediator protein 5 (CRMP5). Carbon 98-99 aldehyde dehydrogenase 1 family, member L1 Mus musculus 124-165 31446906-9 2019 Proteomic analysis revealed that two candidate proteins were obtained in the hippocampus of polyI:C-treated mice, including aldehyde dehydrogenase family 1 member L1 (ALDH1L1) and collapsin response mediator protein 5 (CRMP5). Carbon 98-99 aldehyde dehydrogenase 1 family, member L1 Mus musculus 167-174 31363039-9 2019 We propose that phosphorylation of ZmC4-NADP-ME at Ser419 during the first hours in the light is a cellular mechanism that fine tunes the enzymatic activity to coordinate the carbon concentration mechanism with the CO2 fixation rate, probably to avoid CO2 leakiness from bundle sheath cells. Carbon 175-181 NADP-dependent malic enzyme, chloroplastic Zea mays 40-47 31376937-10 2019 Taken together, our findings suggest that using the Ino-cluster products, C. koseri can exploit the abundant myo-inositol in the brain as a carbon source for growth, thus promoting colonization and virulence. Carbon 140-146 synaptopodin 2 Mus musculus 109-112 28678254-2 2017 In this study, we suggest a novel hybrid hole-transport layer (HTL) consisting of single-walled carbon nanotubes (SWNTs) and poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) for inverted-planar PRV devices. Carbon 96-102 Leucine transport, high Homo sapiens 63-66 31457666-0 2017 Silver Nanowire/Carbon Sheet Composites for Electrochemical Syngas Generation with Tunable H2/CO Ratios. Carbon 16-22 relaxin 2 Homo sapiens 91-96 31457666-3 2017 Herein, we demonstrate the use of Ag nanowire (NW)/porous carbon sheet composite catalysts in the generation of syngas with tunable H2/CO ratios having a large potential window to resist power fluctuation. Carbon 58-64 relaxin 2 Homo sapiens 132-137 31457666-4 2017 These Ag NW/carbon sheet composite catalysts have a potential window increased by 10 times for generating syngas with the proper H2/CO ratio (1.7-2.15) for the Fischer-Tropsch process and an increased syngas production rate of about 19 times compared to that of a Ag foil. Carbon 12-18 relaxin 2 Homo sapiens 129-134 22659048-5 2012 Here we show that expression of GPX1 was induced in medium containing oleic acid as a carbon source in an Msn2/Msn4-dependent manner. Carbon 86-92 stress-responsive transcriptional activator MSN2 Saccharomyces cerevisiae S288C 106-110 28399453-5 2017 X-ray crystallographic analysis of the VDR ligand-binding domain accommodating the three compounds indicates that the oxolane group branched at carbon C22 is not constrained as in case of compound with oxolane group branched at C20 leading to the loss of interactions of the triene group and increased flexibility of the C/D-rings and of the side chain. Carbon 144-150 vitamin D receptor Homo sapiens 39-42 22796747-1 2012 We demonstrate noncovalent electrostatic and pi-pi interactions to assemble semiconducting single wall carbon nanotube (SWCNT)-C(60)@COP nanohybrids. Carbon 103-109 caspase recruitment domain family member 16 Homo sapiens 133-136 28465089-6 2017 Our results establish that lipoxygenase-derived oxylipins produced from 18-carbon PUFA differentially affect multiple adipocyte processes associated with lipid storage and adipokine production. Carbon 75-81 pumilio RNA binding family member 3 Homo sapiens 82-86 22745130-9 2012 However, the K(m) values of pDCR for short chain acyl CoAs are at least 6-fold higher than those for substrates with 10 or more aliphatic carbons. Carbon 138-145 2,4-dienoyl-CoA reductase 2 Homo sapiens 28-32 28577889-2 2017 The association between NOA1 and NO accumulation in Arabidopsis noa1 mutants has been linked to the inability of noa1 mutants to accumulate carbon reserves such as fumarate, leading to chloroplast dysfunction and a pale green leaf phenotype. Carbon 140-146 P-loop containing nucleoside triphosphate hydrolases superfamily protein Arabidopsis thaliana 24-28 28577889-2 2017 The association between NOA1 and NO accumulation in Arabidopsis noa1 mutants has been linked to the inability of noa1 mutants to accumulate carbon reserves such as fumarate, leading to chloroplast dysfunction and a pale green leaf phenotype. Carbon 140-146 P-loop containing nucleoside triphosphate hydrolases superfamily protein Arabidopsis thaliana 64-68 22360849-1 2012 A novel Au-nanoparticles/poly-eriochrome black T film modified glassy carbon electrode (AuNPs/PEBT/GCE) was constructed for the simultaneous determination of l-cysteine (L-Cys) and l-tyrosine (L-Tyr) by differential pulse voltammetry. Carbon 70-76 aminomethyltransferase Homo sapiens 99-102 28417582-0 2017 Hierarchical TiO2 /SnO2 Hollow Spheres Coated with Graphitized Carbon for High-Performance Electrochemical Li-Ion Storage. Carbon 63-69 strawberry notch homolog 2 Homo sapiens 19-22 22765902-4 2012 The structures of these metabolites indicate the essential role of ActVA-ORF4 in ACT biosynthesis, specifically in dimerization of a BIQ intermediate via C-C bond formation. Carbon 82-83 cortactin binding protein 2 Homo sapiens 73-77 28426086-1 2017 Multiple pyrenes as pendants of enantioimpure di-/tripeptides (abbreviated as N-LD-C, N-DL-C, N-LLD-C and N-DDL-C) showed pyrene-origin CPL and CD signals, which were associated with conflicting CPL-/CD-signs, compared to the corresponding enantiopure di-/tri-peptides. Carbon 82-84 hephaestin Homo sapiens 136-139 28426086-1 2017 Multiple pyrenes as pendants of enantioimpure di-/tripeptides (abbreviated as N-LD-C, N-DL-C, N-LLD-C and N-DDL-C) showed pyrene-origin CPL and CD signals, which were associated with conflicting CPL-/CD-signs, compared to the corresponding enantiopure di-/tri-peptides. Carbon 82-84 hephaestin Homo sapiens 195-198 28555106-7 2017 The CYP2A6 expression was increased dose-dependently in increasing 18-carbon FA treated cells. Carbon 70-76 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 4-10 22537085-0 2012 Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice. Carbon 86-92 transformation related protein 53, pseudogene Mus musculus 106-109 28340708-7 2017 PS imprinted carbon nanotube (CNT) and Fe2O3 nanoparticle (SPN) have cavities that are selective for CA 125. Carbon 13-19 DEAF1 transcription factor Homo sapiens 59-62 28340708-7 2017 PS imprinted carbon nanotube (CNT) and Fe2O3 nanoparticle (SPN) have cavities that are selective for CA 125. Carbon 13-19 mucin 16, cell surface associated Homo sapiens 101-107 22513003-1 2012 This paper proposed a direct electrodeposition approach to synthesis of graphene-chitosan (GR-CS) composite onto glassy carbon electrode (GCE) under controlled potential. Carbon 120-126 aminomethyltransferase Homo sapiens 138-141 28013367-6 2017 Using human mesothelial cells, we first demonstrate that asbestos and carbon nanotubes induced caspase-1 activation and high-mobility group box 1, interleukin 1 beta and interleukin 18 secretion was blocked by Cytochalasin D (Cyto D) an actin polymerization inhibitor. Carbon 70-76 interleukin 18 Homo sapiens 170-184 28498696-0 2017 Hyperfine and Spin-Orbit Coupling Effects on Decay of Spin-Valley States in a Carbon Nanotube. Carbon 78-84 spindlin 1 Homo sapiens 14-18 28498696-0 2017 Hyperfine and Spin-Orbit Coupling Effects on Decay of Spin-Valley States in a Carbon Nanotube. Carbon 78-84 spindlin 1 Homo sapiens 54-58 28498696-1 2017 The decay of spin-valley states is studied in a suspended carbon nanotube double quantum dot via the leakage current in Pauli blockade and via dephasing and decoherence of a qubit. Carbon 58-64 spindlin 1 Homo sapiens 13-17 31442042-1 2019 Mitochondrial serine hydroxymethyl transferase isoform 2 (SHMT2) has attracted increasing attention as a pivotal catalyzing regulator of the serine/glycine pathway in the one-carbon metabolism of cancer cells. Carbon 175-181 serine hydroxymethyltransferase 2 Homo sapiens 14-56 28429744-0 2017 A Forest of Sub-1.5-nm-wide Single-Walled Carbon Nanotubes over an Engineered Alumina Support. Carbon 42-48 Rho guanine nucleotide exchange factor 1 Homo sapiens 12-19 31442042-1 2019 Mitochondrial serine hydroxymethyl transferase isoform 2 (SHMT2) has attracted increasing attention as a pivotal catalyzing regulator of the serine/glycine pathway in the one-carbon metabolism of cancer cells. Carbon 175-181 serine hydroxymethyltransferase 2 Homo sapiens 58-63 22798889-1 2012 In the title compound, C(21)H(25)NO(3), the hydro-pyridine ring that constitutes a part of the hexa-hydro-quinoline fused-ring system adopts a sofa conformation; the methine C atom deviates from the least-squares plane defined by the remaining five non-H atoms (r.m.s. Carbon 23-24 hexosaminidase subunit alpha Homo sapiens 95-99 31548257-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2 and EXO70F1. Carbon 22-23 exocyst subunit exo70 family protein E1 Arabidopsis thaliana 99-106 28131450-7 2017 PM1 was composed mostly of organic carbon and ammonium sulfate, while nitrate and crustal elements were major components of the PM10 fraction. Carbon 35-41 transmembrane protein 11 Homo sapiens 0-3 31541095-3 2019 The C-terminal PDZ-binding motif (PDZbm) in OTULIN associates with the cargo-binding site in the PDZ domain of SNX27. Carbon 4-5 OTU deubiquitinase with linear linkage specificity Homo sapiens 44-50 22754551-7 2012 Analysis of ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) genes (cbbL and cbbM) from the sampling port mat and from the borehole fluid demonstrated autotrophic carbon assimilation potential for in situ microbial communities; most cbbL genes were related to those of the sulfur-oxidizing genera Thioalkalivibrio and Thiomicrospira, and cbbM genes were affiliated with uncultured phylotypes from hydrothermal vent plumes and marine sediments. Carbon 172-178 opsin 1, medium wave sensitive Homo sapiens 86-90 31541095-3 2019 The C-terminal PDZ-binding motif (PDZbm) in OTULIN associates with the cargo-binding site in the PDZ domain of SNX27. Carbon 4-5 sorting nexin 27 Homo sapiens 111-116 31246329-0 2019 Highly Selective and Catalytic Oxygenations of C-H and C=C Bonds by a Mononuclear Nonheme High-Spin Iron(III)-Alkylperoxo Species. Carbon 21-22 spindlin 1 Homo sapiens 95-99 31246329-0 2019 Highly Selective and Catalytic Oxygenations of C-H and C=C Bonds by a Mononuclear Nonheme High-Spin Iron(III)-Alkylperoxo Species. Carbon 47-48 spindlin 1 Homo sapiens 95-99 31246329-0 2019 Highly Selective and Catalytic Oxygenations of C-H and C=C Bonds by a Mononuclear Nonheme High-Spin Iron(III)-Alkylperoxo Species. Carbon 47-48 spindlin 1 Homo sapiens 95-99 28421067-4 2017 The results suggested a close association between C-C motif chemokine ligand 2 (CCL2) expressions and ALI induced by a lethal H7N9 virus strain (A/Hebei/01/2013). Carbon 50-51 chemokine (C-C motif) ligand 2 Mus musculus 80-84 28211874-5 2017 We show that ATF4 regulates the expression of one-carbon metabolism genes SHMT2 and NMDMC as a protective response to mitochondrial toxicity. Carbon 50-56 NAD-dependent methylenetetrahydrofolate dehydrogenase Drosophila melanogaster 84-89 22754551-7 2012 Analysis of ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) genes (cbbL and cbbM) from the sampling port mat and from the borehole fluid demonstrated autotrophic carbon assimilation potential for in situ microbial communities; most cbbL genes were related to those of the sulfur-oxidizing genera Thioalkalivibrio and Thiomicrospira, and cbbM genes were affiliated with uncultured phylotypes from hydrothermal vent plumes and marine sediments. Carbon 172-178 opsin 1, medium wave sensitive Homo sapiens 347-351 22568547-9 2012 Charge decomposition analysis (CDA) and extended charge decomposition analysis (ECDA), especially with BP86 shows the similar charge transfer nature of the Co-S bond in GS-Cbl and the Co-C bond in CH(3)Cbl. Carbon 0-1 Cbl proto-oncogene Homo sapiens 172-175 28294252-1 2017 Spin-orbit interaction in carbon nanotubes has been under debate for several years and a variety of theoretical calculations and experimental results have been published. Carbon 26-32 spindlin 1 Homo sapiens 0-4 28165248-0 2017 Molecular Modeling and Adsorption Properties of Ordered Silica-Templated CMK Mesoporous Carbons. Carbon 88-95 cytidine/uridine monophosphate kinase 1 Homo sapiens 73-76 30546072-0 2019 Author Correction: ATF4 regulation of mitochondrial folate-mediated one-carbon metabolism is neuroprotective. Carbon 72-78 activating transcription factor 4 Homo sapiens 19-23 31151011-1 2019 Porous carbon derived from amine-functionalized MIL-125 metal-organic framework (C-MIL-125-NH2) was prepared by carbonization at high temperature under inert atmosphere, and used for adsorption of bisphenol A (BPA) and 4-tert-butylphenol (4-tBP). Carbon 7-13 TATA-box binding protein Homo sapiens 241-244 22568547-9 2012 Charge decomposition analysis (CDA) and extended charge decomposition analysis (ECDA), especially with BP86 shows the similar charge transfer nature of the Co-S bond in GS-Cbl and the Co-C bond in CH(3)Cbl. Carbon 0-1 Cbl proto-oncogene Homo sapiens 202-205 22575126-1 2012 We developed a novel detection method for osteopontin (OPN), a new biomarker for prostate cancer, by attaching a genetically engineered single-chain variable fragment (scFv) protein with high binding affinity for OPN to a carbon nanotube field-effect transistor (NT-FET). Carbon 222-228 secreted phosphoprotein 1 Homo sapiens 42-53 31207328-4 2019 Finally, a novel EIS technique based on interaction of Q and CA-II was developed for sensitive electroanalytical determination of CA-II and in this section of our study, the sensitivity of the developed electroanalytical methodology was improved by the modification of the GCE was with multi-walled carbon nanotubes-ionic liquid. Carbon 299-305 carbonic anhydrase 2 Homo sapiens 130-135 31438886-12 2019 Furthermore, we have noticed that after carbon ion irradiation, circRNA CBL.11 was increased in CRC cells and could function as a competing endogenous RNA (ceRNA) to regulate YWHAE expression by sponging miR-6778-5p, resulting in regulation the proliferation of CRC cells. Carbon 40-46 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon Homo sapiens 175-180 28024754-0 2017 MIPs-graphene nanoplatelets-MWCNTs modified glassy carbon electrode for the determination of cardiac troponin I. Carbon 51-57 troponin I3, cardiac type Homo sapiens 93-111 28024754-1 2017 An electrochemical sensor with high selectivity in addition to sensitivity was developed for the determination of cardiac troponin I (cTnI), based on the modification of cTnI imprinted polymer film on a glassy carbon electrode (GCE). Carbon 210-216 troponin I3, cardiac type Homo sapiens 114-132 28024754-1 2017 An electrochemical sensor with high selectivity in addition to sensitivity was developed for the determination of cardiac troponin I (cTnI), based on the modification of cTnI imprinted polymer film on a glassy carbon electrode (GCE). Carbon 210-216 troponin I3, cardiac type Homo sapiens 134-138 28052423-3 2017 The formation of the preferred (111) oxide is attributed to a unique chemical interaction at the interface between Co3 O4 and carbon, which results in covalent C-O-Co bonds in the hybrid. Carbon 126-132 DAN domain BMP antagonist family member 5 Homo sapiens 160-166 22575126-1 2012 We developed a novel detection method for osteopontin (OPN), a new biomarker for prostate cancer, by attaching a genetically engineered single-chain variable fragment (scFv) protein with high binding affinity for OPN to a carbon nanotube field-effect transistor (NT-FET). Carbon 222-228 secreted phosphoprotein 1 Homo sapiens 55-58 22575126-1 2012 We developed a novel detection method for osteopontin (OPN), a new biomarker for prostate cancer, by attaching a genetically engineered single-chain variable fragment (scFv) protein with high binding affinity for OPN to a carbon nanotube field-effect transistor (NT-FET). Carbon 222-228 secreted phosphoprotein 1 Homo sapiens 213-216 22428663-0 2012 Cell cycle regulation by carboxylated multiwalled carbon nanotubes through p53-independent induction of p21 under the control of the BMP signaling pathway. Carbon 50-56 H3 histone pseudogene 16 Homo sapiens 104-107 28167750-5 2017 Instead, we found that in HCMV-infected cells glucose carbon can be used for lipid synthesis by both ACLY and ACSS2 reactions. Carbon 54-60 ATP citrate lyase Homo sapiens 101-105 31432868-2 2019 This nanocomposite material was employed on the surface of a glassy carbon electrode (GCE) to develop the electrode (FL-DyM/GCE). Carbon 68-74 dymeclin Homo sapiens 120-123 31128396-2 2019 Herein we construct an effective ratiometric fluorescent sensing platform by combining green fluorescent polymer carbon dots (PCDs) and red fluorescent tetraphenylporphyrin tetrasulfonic acid hydrate (TPPS) for specific and visual detection of Hg2+. Carbon 113-119 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 244-247 28241627-6 2017 The experimental results indicate that the IOPO pumped by the hybrid Q-switched laser with AOM and MoS<sub>2</sub>-SA can generate signal wave with shorter pulse duration than those IOPOs pumped by hybrid Q-switched laser with AOM and Cr<sup>4+</sup>:YAG or single-walled carbon nanotube saturable absober (SWCNT-SA) or monolayer graphene SA. Carbon 296-302 MOS proto-oncogene, serine/threonine kinase Homo sapiens 99-102 22428663-1 2012 This report describes how carboxylated multiwalled carbon nanotubes (MWCNTs) induce p53-independent p21 expression and cell cycle arrest. Carbon 51-57 H3 histone pseudogene 16 Homo sapiens 100-103 28102677-2 2017 The reaction proceeded via attack of the C-3 carbon of the indoles onto the C-2 position of the allylic moiety and intramolecular construction of the trifluoromethyl group by the intramolecular fluorine atom shift from the C-2 position to the C-3 position of the allyl unit. Carbon 45-51 complement C3 Homo sapiens 41-44 22732219-6 2012 These results indicate that low nitrate reductase activity due to the AtSIZ1 mutation is correlated with an overall decrease in alternative respiration and with a low carbohydrate content to maintain the carbon to nitrogen ratio in siz1-2 mutants. Carbon 204-210 DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain-containing protein Arabidopsis thaliana 70-76 28102677-2 2017 The reaction proceeded via attack of the C-3 carbon of the indoles onto the C-2 position of the allylic moiety and intramolecular construction of the trifluoromethyl group by the intramolecular fluorine atom shift from the C-2 position to the C-3 position of the allyl unit. Carbon 45-51 complement C3 Homo sapiens 243-246 31457448-0 2017 Hg2+ Sensor Development Based on (E)-N"-Nitrobenzylidene-Benzenesulfonohydrazide (NBBSH) Derivatives Fabricated on a Glassy Carbon Electrode with a Nafion Matrix. Carbon 124-130 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 0-3 31443270-4 2019 In line with previous reports, this study focuses on the apoptotic pathway of BPP, a phenolic glycoside composed of two aromatic rings joined by a seven-carbon chain. Carbon 153-159 sushi repeat containing protein X-linked 2 Homo sapiens 78-81 22426856-4 2012 Expression of each of these plant proteins in a S. cerevisiae ThDP carrier (TPC1) null mutant complemented the growth defect on fermentable carbon sources and restored the level of mitochondrial ThDP and the activity of the mitochondrial ThDP-dependent enzyme acetolactate synthase. Carbon 140-146 thiamine transporter TPC1 Saccharomyces cerevisiae S288C 76-80 31096198-5 2019 Based on the microdosimetric-kinetic (MK) theory, in the 4 mum range for a monolayer cell thickness, the mean RBEalpha (V79 cells) of the carbon ion beam is estimated as 3.612 (late S phase) and 1.737 (G 1/S phase) for the mean LET of 492 keV mum-1. Carbon 138-144 PWWP domain containing 3A, DNA repair factor Homo sapiens 243-248 27907860-1 2017 Present study describes the preparation of a polyethylene glycol-grafted oxidized multi-walled carbon nanotubes (oMWCNTs-PEG) hybrid nanosystem as a carrier of etoposide (VP-16) and Bcl-2 phosphorothioate antisense deoxyoligonucleotides (Aso) to achieve a superior cytostastic efficacy in non-small and small cell lung cancer in vitro. Carbon 95-101 host cell factor C1 Homo sapiens 171-176 21994255-4 2012 Genotype frequencies for MMP-8 -799C/T SNP in arterial disease were C/C (43.5%), C/T (32.3%) and T/T (24.2%), and in the reference group they were C/C (50.0%), C/T (40.0%) and T/T (10.0%; P = 0.012). Carbon 35-36 matrix metallopeptidase 8 Homo sapiens 25-30 28024456-0 2017 Thrombospondin-1 mediates multi-walled carbon nanotube induced impairment of arteriolar dilation. Carbon 39-45 thrombospondin 1 Mus musculus 0-16 31305986-2 2019 Here, non-noble-metal graphene-like carbon nanosheets with trapped Fe species (Fe-N/GPC) are developed by an iron-salt thermally emitted strategy, which integrates the modulation of the electronic structure for boosted intrinsic activity with the engineering of hierarchical porosity for enriched active sites. Carbon 36-42 glycophorin C (Gerbich blood group) Homo sapiens 84-87 31379360-1 2019 BACKGROUND Serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme in one-carbon cell metabolism, including in liver cancer. Carbon 76-82 serine hydroxymethyltransferase 2 Homo sapiens 11-44 31379360-1 2019 BACKGROUND Serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme in one-carbon cell metabolism, including in liver cancer. Carbon 76-82 serine hydroxymethyltransferase 2 Homo sapiens 46-51 27991758-1 2017 We present a new glucose oxidase (GOx)-mediated strategy for detecting glucose based on carbon nanodots supported on silver nanoparticles (C-dots/AgNPs) as nanocomplexes. Carbon 88-94 hydroxyacid oxidase 1 Homo sapiens 17-32 27991758-1 2017 We present a new glucose oxidase (GOx)-mediated strategy for detecting glucose based on carbon nanodots supported on silver nanoparticles (C-dots/AgNPs) as nanocomplexes. Carbon 88-94 hydroxyacid oxidase 1 Homo sapiens 34-37 23005226-6 2012 There is excellent agreement between our carbon-oxygen phase diagram and that predicted by Medin and Cumming. Carbon 41-47 milk fat globule EGF and factor V/VIII domain containing Homo sapiens 91-96 28054656-2 2017 Here, we report the simple dispersion of intact multi-walled carbon nanotubes (CNTs) by adding them directly into an aqueous solution of glucose oxidase (GOx), resulting in simultaneous CNT dispersion and facile enzyme immobilization through sequential enzyme adsorption, precipitation, and crosslinking (EAPC). Carbon 61-67 hydroxyacid oxidase 1 Homo sapiens 137-152 28054656-2 2017 Here, we report the simple dispersion of intact multi-walled carbon nanotubes (CNTs) by adding them directly into an aqueous solution of glucose oxidase (GOx), resulting in simultaneous CNT dispersion and facile enzyme immobilization through sequential enzyme adsorption, precipitation, and crosslinking (EAPC). Carbon 61-67 hydroxyacid oxidase 1 Homo sapiens 154-157 31147890-1 2019 Nitrogen-centered and beta-carbon-centered hydrogen-deficient peptide radicals are considered to be intermediates in the matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD)-induced Calpha-C bond cleavage of peptide backbones when using an oxidizing matrix. Carbon 27-33 carbonic anhydrase 2 Homo sapiens 201-209 22866392-1 2012 Iron-impregnated granular activated carbons (Fe-GAC) can remove arsenic effectively from water. Carbon 36-43 glutaminase Homo sapiens 48-51 28144363-2 2016 The alkenyl iodide moiety of 1,2-oxazine derivatives syn-4 and anti-4 was subsequently exploited for the introduction of new functionalities at the C-5 position by applying palladium-catalyzed carbon-carbon bond-forming reactions such as Sonogashira, Heck, or Suzuki coupling reactions as well as a cyanation reaction. Carbon 193-199 syntrophin gamma 1 Homo sapiens 53-58 28144363-2 2016 The alkenyl iodide moiety of 1,2-oxazine derivatives syn-4 and anti-4 was subsequently exploited for the introduction of new functionalities at the C-5 position by applying palladium-catalyzed carbon-carbon bond-forming reactions such as Sonogashira, Heck, or Suzuki coupling reactions as well as a cyanation reaction. Carbon 200-206 syntrophin gamma 1 Homo sapiens 53-58 30913748-6 2019 Moreover, the stability and capacity of the composites are different from each other due to diverse carbon content, surface area and particle size, in which, SnO2-24%C exhibits better lithium storage performances. Carbon 100-106 strawberry notch homolog 2 Homo sapiens 158-161 22608434-3 2012 The IL-LDH-Mb bionanocomposite was modified on the surface of carbon ionic liquid electrode to get an Mb modified electrode. Carbon 62-68 myoglobin Homo sapiens 11-13 31370354-0 2019 Association of Polymorphisms in Genes Involved in One-Carbon Metabolism with MTHFR Methylation Levels. Carbon 54-60 methylenetetrahydrofolate reductase Homo sapiens 77-82 31370354-1 2019 Methylenetetrahydrofolate reductase (MTHFR) is a pivotal enzyme in the one-carbon metabolism, a metabolic pathway required for DNA synthesis and methylation reactions. Carbon 75-81 methylenetetrahydrofolate reductase Homo sapiens 0-35 31370354-1 2019 Methylenetetrahydrofolate reductase (MTHFR) is a pivotal enzyme in the one-carbon metabolism, a metabolic pathway required for DNA synthesis and methylation reactions. Carbon 75-81 methylenetetrahydrofolate reductase Homo sapiens 37-42 27960513-3 2016 Herein, we report highly conductive porous Na-embedded carbon (Na@C) nanowalls with large surface areas, which have been synthesized by an invented reaction of CO with liquid Na. Carbon 55-61 X-linked Kx blood group Homo sapiens 63-67 27934112-4 2016 Herein, we developed a bioelectronic nose using a carbon nanotube (CNT) field-effect transistor (FET) functionalized with Drosophila odorant binding protein (OBP)-derived peptide for easy and rapid detection of Salmonella contamination in ham. Carbon 50-56 Optix-binding protein Drosophila melanogaster 133-156 27934112-4 2016 Herein, we developed a bioelectronic nose using a carbon nanotube (CNT) field-effect transistor (FET) functionalized with Drosophila odorant binding protein (OBP)-derived peptide for easy and rapid detection of Salmonella contamination in ham. Carbon 50-56 Optix-binding protein Drosophila melanogaster 158-161 31370354-3 2019 We performed the present study to investigate if common polymorphisms in one-carbon metabolism genes contribute to MTHFR methylation levels. Carbon 77-83 methylenetetrahydrofolate reductase Homo sapiens 115-120 22525679-5 2012 In the presence of a fermentable carbon source, UGA4 expression is induced by GABA while in the presence of a non-fermentable carbon source this expression is GABA-independent. Carbon 33-39 Uga4p Saccharomyces cerevisiae S288C 48-52 22525679-7 2012 We found that although the subcellular localization of Gln3 depends on the carbon source and UGA4 expression depends on Tor1 and Snf1, Gln3 localization does not depend on these kinases. Carbon 75-81 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 55-59 22525679-8 2012 We also found that the phosphorylation of Gln3 is mediated by two systems activated by a non-fermentable carbon source, involving the Snf1 kinase and an unidentified TORC1-regulated kinase. Carbon 105-111 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 42-46 31352538-1 2019 Cerium vanadate resembling the shape of a hedgehog were interconnected with carbon nanofibers to give a heterostructure (referred to as CeV/CNF) that exhibits efficient catalytic activity for the electrochemical detection of the drug nilutamide (NLT). Carbon 76-82 NPHS1 adhesion molecule, nephrin Homo sapiens 140-143 27876872-4 2016 The TGA results indicated that the PM produced by P20 had the highest moisture and volatility contents and the fastest oxidation rate of solid carbon followed by P10 and P0 derived PM. Carbon 143-149 tubulin polymerization promoting protein family member 3 Homo sapiens 50-53 31352538-3 2019 A glassy carbon electrode was modified with the CeV/CNF nanocomposite. Carbon 9-15 NPHS1 adhesion molecule, nephrin Homo sapiens 52-55 22525679-9 2012 We also found that the activity of the main transcription factors responsible for UGA4 induction by GABA varies depending on the quality of the carbon source. Carbon 144-150 Uga4p Saccharomyces cerevisiae S288C 82-86 22525679-10 2012 In a fermentable carbon source such as glucose, the negative GATA factor Dal80 binds to UGA4 promoter; only after the addition of the inducer, the positive factors Uga3, Dal81 and Gln3 interact with the promoter removing Dal80 and leading to gene induction. Carbon 17-23 Uga4p Saccharomyces cerevisiae S288C 88-92 27854316-4 2016 Deficient or low status of these B-vitamins alone or in combination with genetic polymorphisms, including the common MTHFR 677 C T polymorphism, could contribute to greater disease risk in ageing by causing perturbations in one carbon metabolism. Carbon 230-236 methylenetetrahydrofolate reductase Homo sapiens 117-122 22525679-10 2012 In a fermentable carbon source such as glucose, the negative GATA factor Dal80 binds to UGA4 promoter; only after the addition of the inducer, the positive factors Uga3, Dal81 and Gln3 interact with the promoter removing Dal80 and leading to gene induction. Carbon 17-23 Dal81p Saccharomyces cerevisiae S288C 170-175 31273205-3 2019 Here, we demonstrate the feasibility of a highly-efficient and potentially-continuous fiber-spinning method to produce high-performance carbon nanotube (CNT) fiber (CNTF). Carbon 136-142 ciliary neurotrophic factor Homo sapiens 165-169 30693532-5 2019 Disruption of methionine synthase has wide-ranging implications for all methylation-dependent reactions, including epigenetic modification, but also for the intracellular folate pathway, since methionine synthase uses 5-methyltetrahydrofolate as a one-carbon donor. Carbon 252-258 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 14-33 22525679-10 2012 In a fermentable carbon source such as glucose, the negative GATA factor Dal80 binds to UGA4 promoter; only after the addition of the inducer, the positive factors Uga3, Dal81 and Gln3 interact with the promoter removing Dal80 and leading to gene induction. Carbon 17-23 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 180-184 27762342-0 2016 Thermal treatment of hair for the synthesis of sustainable carbon quantum dots and the applications for sensing Hg2. Carbon 59-65 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 112-115 22525679-11 2012 In contrast, in the non-fermentable carbon source acetate the negative GATA factor remains bound to UGA4 promoter in the presence or absence of GABA, the positive factors are not detected bound in any of these conditions and in consequence, UGA4 is not induced. Carbon 36-42 Uga4p Saccharomyces cerevisiae S288C 100-104 22525679-11 2012 In contrast, in the non-fermentable carbon source acetate the negative GATA factor remains bound to UGA4 promoter in the presence or absence of GABA, the positive factors are not detected bound in any of these conditions and in consequence, UGA4 is not induced. Carbon 36-42 Uga4p Saccharomyces cerevisiae S288C 241-245 30693532-5 2019 Disruption of methionine synthase has wide-ranging implications for all methylation-dependent reactions, including epigenetic modification, but also for the intracellular folate pathway, since methionine synthase uses 5-methyltetrahydrofolate as a one-carbon donor. Carbon 252-258 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 193-212 22231731-15 2012 Iloprost downregulated poly I:C-induced histone H3K4 trimethylation in the TNFA gene promoter region via suppressing translocation of histone 3 lysine 4 (H3K4)-specific methyltransferases MLL (mixed lineage leukemia) and WDR5 (WD repeat domain 5). Carbon 30-31 lysine methyltransferase 2A Homo sapiens 188-191 27607901-1 2016 The homofullerene compound cis-2-C60 (CF2 )2 , which has an unusual kind of open/closed valence tautomerism undergoes consecutive regioselective hydrogenation at bridgehead carbon atoms upon reduction with Zn/Cu couple in H2 O-toluene mixture. Carbon 173-179 ATPase H+ transporting accessory protein 1 Homo sapiens 38-41 27607901-2 2016 The tautomerism barrier in cis-2-C60 (CF2 )2 is negligible in the neutral state, whereas negative charging both impedes tautomeric transformation and promotes regioselective addition of electrophilic species at the bridgehead carbon atoms. Carbon 226-232 ATPase H+ transporting accessory protein 1 Homo sapiens 38-41 27633149-1 2016 Extremely short (<1 nm) fragments of zig-zag carbon nanotubes are studied with ab-initio techniques to determine their geometric and electronic structure as well as their magnetic susceptibility. Carbon 48-54 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 44-47 27633149-2 2016 It is found that for lengths of a few carbon-carbon bonds, each fragment can be viewed as composed of crowns, that is, zig-zag rings of carbon atoms along the circumference of the tube. Carbon 38-44 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 123-126 31109763-2 2019 Several recent reports show that increasing the capacity of plants to assimilate carbon (source strength), or to tap into the internal carbon reservoir (sink strength), has the potential to improve plant productivity in the field under water-deficit conditions. Carbon 135-141 nuclear RNA export factor 1 Homo sapiens 113-116 22560225-4 2012 By converting acetyl-CoA to its membrane permeant acetylcarnitine ester, CrAT regulates mitochondrial and intracellular carbon trafficking. Carbon 120-126 carnitine O-acetyltransferase Homo sapiens 73-77 31275928-6 2019 Notably, the CoFe-CNTF derived from bimetallic CoFe-MOFs achieves a high ion adsorption capacity of 37.0 mg g-1, superior to most of recently reported carbon-based materials. Carbon 151-157 ciliary neurotrophic factor Homo sapiens 18-22 31106785-1 2019 Catalytic transformations of syngas (a mixture of H2 and CO), which is one of the most important C1-chemistry platforms, and CO2, a greenhouse gas released from human industrial activities but also a candidate of abundant carbon feedstock, into chemicals and fuels have attracted much attention in recent years. Carbon 222-228 relaxin 2 Homo sapiens 50-59 31125206-0 2019 Carbones and Heavier Ylidones (EL2) in Frustrated Lewis Pair Chemistry: Influence of the Nature of EL2 on Dihydrogen Activation. Carbon 0-8 spectrin alpha, erythrocytic 1 Homo sapiens 99-102 27633149-2 2016 It is found that for lengths of a few carbon-carbon bonds, each fragment can be viewed as composed of crowns, that is, zig-zag rings of carbon atoms along the circumference of the tube. Carbon 45-51 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 123-126 27633149-2 2016 It is found that for lengths of a few carbon-carbon bonds, each fragment can be viewed as composed of crowns, that is, zig-zag rings of carbon atoms along the circumference of the tube. Carbon 45-51 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 123-126 27659093-10 2016 When screened against a series of alcohols, thiols, sulfides, and metal-coordinating ligands, OR2T11 responds with enhancement by copper to the mouse semiochemical CH3SCH2SH and derivatives, to four-membered cyclic sulfide thietane and to one- to four-carbon straight- and branched-chain and five-carbon branched-chain thiols but not to longer chain thiols, suggesting compact receptor dimensions. Carbon 252-258 olfactory receptor family 2 subfamily T member 11 Homo sapiens 94-100 27659093-10 2016 When screened against a series of alcohols, thiols, sulfides, and metal-coordinating ligands, OR2T11 responds with enhancement by copper to the mouse semiochemical CH3SCH2SH and derivatives, to four-membered cyclic sulfide thietane and to one- to four-carbon straight- and branched-chain and five-carbon branched-chain thiols but not to longer chain thiols, suggesting compact receptor dimensions. Carbon 297-303 olfactory receptor family 2 subfamily T member 11 Homo sapiens 94-100 31125206-1 2019 The role of carbones (CL2; L = phosphines vs carbenes) as Lewis bases in dihydrogen (H2) activation reactions in the presence of the Lewis acid B(C6F5)3 has been computationally explored by means of density functional theory calculations. Carbon 12-20 endogenous retrovirus group W member 5 Homo sapiens 22-25 27782413-4 2016 That the Cl atom adds to both carbons of the C=C bond of isobutene with the terminal site slightly favored is consistent with the energies of products predicted theoretically, but is in contrast to the reaction of Cl + propene in solid p-H2 in which the addition of Cl to mainly the central C atom was previously reported. Carbon 9-10 polyhomeotic homolog 2 Homo sapiens 236-240 22306658-2 2012 In Saccharomyces cerevisiae, changes in carbon source lead to gene induction by Adr1 and Cat8 that are known to require the upstream function of the Snf1 protein kinase, the central regulator of carbon metabolism, to exert their activating effect. Carbon 40-46 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 89-93 27541683-12 2016 MTHFR C677T and SLC19A1 G80A are the two polymorphisms of one-carbon metabolic pathway that increase breast cancer in the worldwide population. Carbon 62-68 methylenetetrahydrofolate reductase Homo sapiens 0-5 31124676-4 2019 Mechanistic studies indicate that the C-N bond formation occurs via a syn amino-palladation mechanism, an insight which may guide future reaction development given the limited number of enantioselective syntheses of alpha-tertiary amines. Carbon 38-39 synemin Homo sapiens 70-73 30991223-11 2019 With increasing carbon chain lengths of individual PFCAs (C4-C8), the logarithm of their BAFs for edible parts of various crops showed a linear decrease (0.1-1.16 log decrease per CF2 unit), and the largest decrease was observed in grains. Carbon 16-22 ATPase H+ transporting accessory protein 1 Homo sapiens 180-183 22306658-2 2012 In Saccharomyces cerevisiae, changes in carbon source lead to gene induction by Adr1 and Cat8 that are known to require the upstream function of the Snf1 protein kinase, the central regulator of carbon metabolism, to exert their activating effect. Carbon 195-201 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 89-93 27560935-2 2016 We herein describe an intriguing property of Na2(5"-GMP) to form blue emitting chiral carbon dots (G-dots) that exhibit excitation dependent down-conversion and up-conversion fluorescence signature and self-assemble to form fluorescent hydrogels. Carbon 86-92 5'-nucleotidase, cytosolic II Homo sapiens 52-55 21881950-8 2012 In addition, a statistically significant acute lap effect on C(r) was observed at the end of the second and third laps (by 11.4 and 7.2%, respectively). Carbon 61-62 LAP Homo sapiens 47-50 27559608-0 2016 Tracking Pseudocapacitive Contribution to Superior Energy Storage of MnS Nanoparticles Grown on Carbon Textile. Carbon 96-102 glycophorin E (MNS blood group) Homo sapiens 69-72 27659937-12 2016 The expression of MMP-2 and MMP-9 in H-vector and HsiI showed different pattern after carbon ion exposure. Carbon 86-92 matrix metallopeptidase 9 Homo sapiens 28-33 30858030-4 2019 Compared with PM2.5, PM1 is smaller in size, has a larger surface area and absorbs more toxic substances such as heavy metals, organic compounds, and black carbon. Carbon 156-162 transmembrane protein 11 Homo sapiens 21-24 31223444-1 2019 Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) plays a key role in one-carbon (1C) metabolism in human mitochondria, and its high expression correlates with poor survival of patients with various types of cancer. Carbon 75-81 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 0-41 22147491-0 2012 Raman spectroscopy as a detection and analysis tool for in vitro specific targeting of pancreatic cancer cells by EGF-conjugated, single-walled carbon nanotubes. Carbon 144-150 epidermal growth factor Homo sapiens 114-117 31223444-1 2019 Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) plays a key role in one-carbon (1C) metabolism in human mitochondria, and its high expression correlates with poor survival of patients with various types of cancer. Carbon 75-81 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 43-49 31172013-4 2019 Here, we show that carbon source, an essential nutrient, impacts Rnr1 and Rnr3 abundance: Non-fermentable carbon sources or limiting concentrations of glucose down regulate Rnr1 and induce Rnr3 expression. Carbon 19-25 ribonucleotide-diphosphate reductase subunit RNR1 Saccharomyces cerevisiae S288C 65-69 31172013-4 2019 Here, we show that carbon source, an essential nutrient, impacts Rnr1 and Rnr3 abundance: Non-fermentable carbon sources or limiting concentrations of glucose down regulate Rnr1 and induce Rnr3 expression. Carbon 19-25 ribonucleotide-diphosphate reductase subunit RNR1 Saccharomyces cerevisiae S288C 173-177 31172013-4 2019 Here, we show that carbon source, an essential nutrient, impacts Rnr1 and Rnr3 abundance: Non-fermentable carbon sources or limiting concentrations of glucose down regulate Rnr1 and induce Rnr3 expression. Carbon 106-112 ribonucleotide-diphosphate reductase subunit RNR1 Saccharomyces cerevisiae S288C 65-69 31172013-4 2019 Here, we show that carbon source, an essential nutrient, impacts Rnr1 and Rnr3 abundance: Non-fermentable carbon sources or limiting concentrations of glucose down regulate Rnr1 and induce Rnr3 expression. Carbon 106-112 ribonucleotide-diphosphate reductase subunit RNR1 Saccharomyces cerevisiae S288C 173-177 31172013-6 2019 The carbon source dependent regulation of Rnr3 is mediated by Mec1, the budding yeast ATM/ATR checkpoint response kinase. Carbon 4-10 protein kinase MEC1 Saccharomyces cerevisiae S288C 62-66 22147491-1 2012 Single-walled carbon nanotubes (SWCNTs) were covalently linked to epidermal growth factor (EGF) proteins through an esterification process that was found to be responsible for the docking of SWCNTs on the human pancreatic cancer cells (PANC-1) surface, thus providing a mechanism for the enhanced delivery and internalization of the nanotubes. Carbon 14-20 epidermal growth factor Homo sapiens 66-89 31172013-9 2019 Together, these results unveil involvement of Rnr3 in mitochondrial functions and Mec1 in mediating the carbon source dependent regulation of Rnr3. Carbon 104-110 protein kinase MEC1 Saccharomyces cerevisiae S288C 82-86 22147491-1 2012 Single-walled carbon nanotubes (SWCNTs) were covalently linked to epidermal growth factor (EGF) proteins through an esterification process that was found to be responsible for the docking of SWCNTs on the human pancreatic cancer cells (PANC-1) surface, thus providing a mechanism for the enhanced delivery and internalization of the nanotubes. Carbon 14-20 epidermal growth factor Homo sapiens 91-94 22210453-1 2012 CYP27A1 is a mitochondrial cytochrome P450 which can hydroxylate vitamin D3 and cholesterol at carbons 25 and 26, respectively. Carbon 95-102 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 0-7 30909017-3 2019 Therefore, the present paper reports, for the first time, the construction and application of a label-free impedimetric immunosensor to detect DHEAS, which was based on the modification of an oxidized glassy carbon electrode with arginine-functionalized gold nanoparticles (AuNPs-ARG) and anti-DHEA IgM antibodies (ox-GCE/AuNPs-ARG/IgM). Carbon 208-214 sulfotransferase family 2A member 1 Homo sapiens 143-148 22269069-8 2012 AtPAP2 is the first PAP shown to modulate carbon metabolism and the first shown to be dual-targeted to both plastids and mitochondria by a C-terminal targeting signal. Carbon 42-48 Purple acid phosphatases superfamily protein Arabidopsis thaliana 0-6 30772575-1 2019 The current investigation deals with how chemically activated carbon derived from industrial paper sludge (ACPS) performs on sorptive removal of enrofloxacin (ENF), an antibacterial drug from its water solution. Carbon 62-68 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Homo sapiens 107-111 22269069-10 2012 This might reflect a common ancestral function of AtPAP2-like sequences in the regulation of carbon metabolism. Carbon 93-99 Purple acid phosphatases superfamily protein Arabidopsis thaliana 50-56 30771935-3 2019 And the selective detection performance of dopamine (DA) on PIL-GP modified glassy carbon electrode (GCE) were further explored by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Carbon 83-89 serpin family A member 2 (gene/pseudogene) Homo sapiens 60-63 22540597-6 2012 Carbon and oxygen atoms are arranged in CO4 tetrahedral units linked by oxygen atoms at the corners. Carbon 0-6 complement C4A (Rodgers blood group) Homo sapiens 40-43 30945849-3 2019 In this study, we focused on geometric isomers cis- and trans-2,3-butylene carbonates ( c/ t-BC) as model electrolytes. Carbon 20-21 TBC1 domain family member 1 Homo sapiens 91-95 31018808-4 2019 Higher percentages of TLR2, TLR3, TLR4, and TLR7 were expressed on such lymphocytes, and the TLR agonists PGN, Poly I:C, LPS, and R848 induced a higher level of IFN-gamma. Carbon 118-119 toll-like receptor 7 Mus musculus 44-48 21549726-7 2012 Furthermore, we observed an increase in peripheral poly I:C-induced IL-6, TNF-alpha, MCP-1, and MIP-1alpha, but not IL-1beta. Carbon 58-59 chemokine (C-C motif) ligand 3 Mus musculus 96-106 22461784-1 2012 ATIC, SHMT2, and SLC46A1 have essential roles in one-carbon (1-C) transfer. Carbon 53-59 solute carrier family 46 member 1 Homo sapiens 17-24 31107022-7 2019 LT4, MT3, and HT2 improved the recalcitrant carbon by 71%, 69% and 75%, respectively, which was significantly higher than the increment of two labile carbon pools. Carbon 44-50 metallothionein 3 Homo sapiens 5-8 31107022-7 2019 LT4, MT3, and HT2 improved the recalcitrant carbon by 71%, 69% and 75%, respectively, which was significantly higher than the increment of two labile carbon pools. Carbon 150-156 metallothionein 3 Homo sapiens 5-8 25585635-3 2012 A glassy carbon electrode was used as a substrate to immobilize, in the first instance, horse heart cytochrome c (HHC) in a gelatin matrix. Carbon 9-15 cytochrome c, somatic Equus caballus 100-112 30550968-3 2019 Herein, we fabricated the carbon dots/fatty acid-coated MNPs (CDs/C11-Fe3O4) through a facile and simple method. Carbon 26-32 aldo-keto reductase family 1 member C4 Homo sapiens 66-69 22352786-2 2012 Despite their broad interest, fundamental questions about their reaction mechanism remain to be answered, especially for those GTs that transfer the sugar with net retention of the configuration at the anomeric carbon (retaining glycosyltransferases, ret-GTs). Carbon 211-217 ret proto-oncogene Homo sapiens 164-167 30989391-1 2019 A carbon nanofiber functionalized with ruthenium(II)-tetrasulfonato phenyl porphine (CNF/Ru-TSPP) is shown to be viable sensor for amperometric determination of the antipsychotic drug chlorpromazine (CPZ). Carbon 2-8 NPHS1 adhesion molecule, nephrin Homo sapiens 85-88 30989391-8 2019 Graphical abstract Schematic presentation of carbon nanofiber/ tetrasulfonatophenyl Ruthenium(II)porphine (CNF/Ru-TSPP) nanocomposite synthesis and application for the electrochemical determination of chlorpromazine (CPZ). Carbon 45-51 NPHS1 adhesion molecule, nephrin Homo sapiens 107-110 30788873-4 2019 Taking the SnS2 /SnO2 couple as an example, SnS2 /SnO2 nanosheet heterostructures on carbon nanofibers (CNFs), named C@SnS2 /SnO2 , were designed and synthesized. Carbon 85-91 strawberry notch homolog 2 Homo sapiens 17-20 22247542-7 2012 Interestingly, DHHC2 efficiently transferred acyl chains 14 carbons and longer, whereas DHHC3 activity was greatly reduced by acyl-CoAs with chain lengths longer than 16 carbons. Carbon 170-177 zinc finger DHHC-type palmitoyltransferase 3 Homo sapiens 88-93 30888173-7 2019 TRS benzenoid hydrocarbons are those isomers in benzenoids having their number of formula carbons divisible by six and a maximum number of perimeter bay regions (etao) given by eta0(TRS) = (1/2) NH(sextet) - 3 + F. NH(sextet) is the number of formula hydrogens and F is the number of perimeter fjords (triplet of adjacent bay regions); for strain-free TRS benzenoids, F = 0. Carbon 19-26 tRNA-Ser (anticodon TGA) 2-1 Homo sapiens 177-193 22755027-3 2012 In the present study, we examined the effects of multi-wall carbon nanotubes (MWCNTs) on the receptor activator of nuclear factor kappaB ligand (RANKL)-supported osteoclastogenesis using a murine monocytic cell line RAW 264.7. Carbon 60-66 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 93-143 30329167-3 2019 In HBs-Tg mice, poly (I:C) induced liver inflammation with markedly increased infiltrating lymphocytes, along with the concurrently increased apoptosis and proliferation of hepatocytes, leading to the accelerated epithelial-to-mesenchymal transition (EMT) of hepatocytes shown by increased expression of the typical transcriptional factors (Slug, Twist, and mothers against decapentaplegic-interacting protein 1) and phenotypic proteins (vimentin and chemokine [C-X-C motif] receptor 4). Carbon 24-25 vimentin Mus musculus 438-446 30329167-3 2019 In HBs-Tg mice, poly (I:C) induced liver inflammation with markedly increased infiltrating lymphocytes, along with the concurrently increased apoptosis and proliferation of hepatocytes, leading to the accelerated epithelial-to-mesenchymal transition (EMT) of hepatocytes shown by increased expression of the typical transcriptional factors (Slug, Twist, and mothers against decapentaplegic-interacting protein 1) and phenotypic proteins (vimentin and chemokine [C-X-C motif] receptor 4). Carbon 24-25 chemokine (C-X-C motif) receptor 4 Mus musculus 451-485 22755027-3 2012 In the present study, we examined the effects of multi-wall carbon nanotubes (MWCNTs) on the receptor activator of nuclear factor kappaB ligand (RANKL)-supported osteoclastogenesis using a murine monocytic cell line RAW 264.7. Carbon 60-66 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 145-150 22241585-4 2012 We established HCN, CO, and CH(3)SH as carbon nutrients, CO and H(2) as reductants, and iron-group transition metals as catalysts. Carbon 39-45 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 15-18 30824053-2 2019 In addition to carbon fixation activity in C4 photosynthesis, NADP-dependent malic enzyme (NADP-ME) has been suggested to play important roles in diverse stress responses in plants. Carbon 15-21 malic enzyme 1 Homo sapiens 62-89 30824053-2 2019 In addition to carbon fixation activity in C4 photosynthesis, NADP-dependent malic enzyme (NADP-ME) has been suggested to play important roles in diverse stress responses in plants. Carbon 15-21 malic enzyme 1 Homo sapiens 91-98 22063315-4 2012 The prepared anti-AFP/GNPs/TMCS-MPS particles were used to modify glassy carbon electrode (GCE) to construct a label-free immunosensor. Carbon 73-79 aminomethyltransferase Homo sapiens 91-94 30855956-0 2019 Spin-Coupled Generalized Valence Bond Description of Group 14 Species: The Carbon, Silicon and Germanium Hydrides, XH n ( n = 1-4). Carbon 75-81 spindlin 1 Homo sapiens 0-4 22336952-2 2012 Dependencies of silicon and C-1 carbon chemical shifts on Hammett substituent constants are discussed. Carbon 32-38 heterogeneous nuclear ribonucleoprotein C Homo sapiens 28-31 30934702-1 2019 The present paper describes the preparation and characterization of a graphene, chitosan, platinum nanoparticles and tyrosinase-based bionanocomposite film deposited on the surface of a screen-printed carbon electrode for the detection of L-tyrosine by voltammetry. Carbon 201-207 tyrosinase Homo sapiens 117-127 22284455-3 2012 The novel G-CdS QDs-agarose composite was first coated on the glass carbon electrode surface to form a robust film, which exhibited high ECL intensity, good biocompatibility and high stability. Carbon 68-74 CDP-diacylglycerol synthase 1 Homo sapiens 12-15 30785716-2 2019 Hence, heterostructured SnS2/Mn2SnS4/carbon nanoboxes (SMS/C NBs) have been developed by a facial wet-chemical method and utilized as the anode material of sodium ion batteries. Carbon 37-43 spermine synthase Homo sapiens 55-64 30785716-5 2019 Moreover, the heterostructured SMS coupled with the interacting carbon network provides efficient channels for electrons and Na+ diffusion, resulting in an excellent rate performance. Carbon 64-70 spermine synthase Homo sapiens 31-34 22031784-3 2012 The purpose of this investigation was to examine the effects of dietary vitamin E and C (Vit E/C) supplementation on DEX-induced glucose intolerance in rats. Carbon 86-87 vitrin Rattus norvegicus 89-92 22452184-6 2012 Principal components analysis (PCA) indicated that twenty categories of carbon significantly related to PC1 and twelve categories for PC2. Carbon 72-78 polycystin 1, transient receptor potential channel interacting Homo sapiens 104-107 30976531-6 2019 We demonstrate this method with solubilized envelope (Env) proteins from HIV, which typically show a restricted orientation on continuous carbon film, and show the following: 1-octadecanol added to negative stain aids the formation of a continuous sample-stain layer spanning the holes of a holey carbon film. Carbon 138-144 endogenous retrovirus group K member 20 Homo sapiens 44-52 30976531-6 2019 We demonstrate this method with solubilized envelope (Env) proteins from HIV, which typically show a restricted orientation on continuous carbon film, and show the following: 1-octadecanol added to negative stain aids the formation of a continuous sample-stain layer spanning the holes of a holey carbon film. Carbon 138-144 endogenous retrovirus group K member 20 Homo sapiens 54-57 30868250-1 2019 An antifouling electrochemical aptasensor for ATP is described that has a zwitterionic self-assembled sensing interface on a glassy carbon electrode modified with a reduced graphene oxide carbon nanofiber (GO-CNF). Carbon 188-194 NPHS1 adhesion molecule, nephrin Homo sapiens 209-212 30848371-7 2019 Graphical abstract Schematic presentation of the water-soluble nitrogen-doped carbon dots (C-dots) as a fluorescent probe for Cr6+ based on an inner filter effect. Carbon 78-84 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 126-129 27402268-1 2016 Carboranes are a class of carbon-containing polyhedral boron cluster compounds with globular geometry and hydrophobic surface that interact with hormone receptors such as estrogen receptor (ER) and androgen receptor (AR). Carbon 26-32 androgen receptor Mus musculus 198-215 27402268-1 2016 Carboranes are a class of carbon-containing polyhedral boron cluster compounds with globular geometry and hydrophobic surface that interact with hormone receptors such as estrogen receptor (ER) and androgen receptor (AR). Carbon 26-32 androgen receptor Mus musculus 217-219 22452184-6 2012 Principal components analysis (PCA) indicated that twenty categories of carbon significantly related to PC1 and twelve categories for PC2. Carbon 72-78 chromobox 4 Homo sapiens 134-137 27660434-0 2016 Carbon nanotube-based substrates promote cardiogenesis in brown adipose-derived stem cells via beta1-integrin-dependent TGF-beta1 signaling pathway. Carbon 0-6 integrin subunit beta 1 Homo sapiens 95-109 22192195-11 2012 Use of recombinant bovine somatotropin reduced resource use and waste output in supplemented populations, with decreases in carbon footprint equivalent to 10.0% (Jersey) and 7.5% (Holstein) compared with nonsupplemented populations. Carbon 124-130 somatotropin Bos taurus 26-38 27422997-0 2016 Role of mesothelin in carbon nanotube-induced carcinogenic transformation of human bronchial epithelial cells. Carbon 22-28 mesothelin Homo sapiens 8-18 27311564-3 2016 We based our work on the previous observation that Esa1p acetylates and activates phosphoenolpyruvate carboxykinase (PEPCK) encoded by PCK1, a rate-limiting enzyme in gluconeogenesis, and subsequently evaluated the activation of Pck1p by yeast growth with non-fermentable carbon sources, thus dependent on gluconeogenesis. Carbon 272-278 NuA4 histone acetyltransferase complex catalytic subunit ESA1 Saccharomyces cerevisiae S288C 51-56 30508574-5 2019 Only n3 PUFAs prevented poly I:C-induced deficits in BDNF. Carbon 31-32 brain derived neurotrophic factor Homo sapiens 53-57 22017456-0 2011 Energy transfer from CdSe/CdS nanorods to amorphous carbon. Carbon 52-58 CDP-diacylglycerol synthase 1 Homo sapiens 21-24 30941196-6 2019 Even more interesting is that a treatment of the ILF sample with activated carbon reduced its cytotoxicity and increased the IL-10 release (3.1 times). Carbon 75-81 interleukin 10 Homo sapiens 125-130 27033943-1 2016 The Vc2 riboswitch possesses an aptamer domain belonging to the class-I c-di-GMP riboswitch family. Carbon 5-6 5'-nucleotidase, cytosolic II Homo sapiens 77-80 22158683-2 2011 The formation of an acyclic boronate ester by the attachment of a hydride ion at C-1 indicated that the unexpected endocyclic cleavage of the bond between the anomeric carbon atom and the pyranose ring oxygen atom proceeded via an oxacarbenium ion intermediate produced by the chelation between O5/O6 of the pyranoside and the Lewis acid, followed by nucleophile substitution with a hydride ion at C1. Carbon 168-174 heterogeneous nuclear ribonucleoprotein C Homo sapiens 81-84 27566173-0 2016 (13)C-NMR studies on disulfide bond isomerization in bovine pancreatic trypsin inhibitor (BPTI). Carbon 4-5 spleen trypsin inhibitor I Bos taurus 53-88 27566173-0 2016 (13)C-NMR studies on disulfide bond isomerization in bovine pancreatic trypsin inhibitor (BPTI). Carbon 4-5 spleen trypsin inhibitor I Bos taurus 90-94 29187119-8 2019 Also, the TiO2-SnO2 catalyst was effective in complete mineralization of diclofenac with a maximum total organic carbon removal of 90% achieved under ultraviolet irradiation. Carbon 113-119 strawberry notch homolog 2 Homo sapiens 15-18 31459640-2 2019 A strong loss of functional groups during pyrolysis at temperatures beyond 300 C of the HTC-derived hydrochars was observed, resulting in an increase of the carbon content up to 95 wt% for the carbon materials pyrolyzed at 800 C and an increase of the specific surface area with a maximum of 520 m2 g-1 at a pyrolysis temperature of 600 C. Devolatilization mainly took place in the range from 300 to 500 C, releasing light pyrolysis gases such as CO, CO2, H2O and larger oxygen-containing molecules up to C11. Carbon 194-200 RNA polymerase III subunit K Homo sapiens 509-512 21725842-3 2011 The aim of this study was to assess the effects, after intraperitoneal (ip) injection, of functionalized multi-walled carbon nanotubes (MWCNT) (carboxyl groups) on various hepatotoxicity and oxidative stress biomarkers (ROS, LHP, ALT, AST, ALP, and morphology of liver) in the mouse model. Carbon 118-124 glutamic pyruvic transaminase, soluble Mus musculus 230-233 30227284-3 2019 However, the 1920s mining industry was established in Slovenia, which emitted carbon dust into the Sava River. Carbon 78-84 T-box transcription factor T Homo sapiens 99-103 27103024-1 2016 UNLABELLED: A good-manufacturing-practices (GMP) (68)Ge/(68)Ga generator that uses modified dodecyl-3,4,5-trihydroxybenzoate hydrophobically bound to a octadecyl silica resin (C-18) as an adsorbent has been developed that allows for dilute HCl (0.05N) to efficiently elute metal-impurity-free (68)Ga(3+) ready for peptide labeling. Carbon 176-177 5'-nucleotidase, cytosolic II Homo sapiens 44-47 22035958-3 2011 Our studies identify a conserved regulatory circuit in which SREBP-1 controls genes in the one-carbon cycle, which produces the methyl donor S-adenosylmethionine (SAMe). Carbon 95-101 sterol regulatory element binding transcription factor 1 Homo sapiens 61-68 27391339-2 2016 Increased de novo biosynthesis of glycine by serine hydroxymethyltransferase 2 (SHMT2) is the central mechanism to fuel one-carbon pools supporting tumorigenesis. Carbon 124-130 serine hydroxymethyltransferase 2 Homo sapiens 45-78 30718580-0 2019 An investigation into non-covalent functionalization of a single-walled carbon nanotube and a graphene sheet with protein G:A combined experimental and molecular dynamics study. Carbon 72-78 proline rich protein BstNI subfamily 3 Homo sapiens 114-123 30718580-3 2019 Herein, PrG interaction with single-walled carbon nanotube (SWCNT) and graphene (Gra) nanostructures was studied by employing experimental and MD simulation techniques. Carbon 43-49 proline rich protein BstNI subfamily 3 Homo sapiens 8-11 27391339-2 2016 Increased de novo biosynthesis of glycine by serine hydroxymethyltransferase 2 (SHMT2) is the central mechanism to fuel one-carbon pools supporting tumorigenesis. Carbon 124-130 serine hydroxymethyltransferase 2 Homo sapiens 80-85 22219823-1 2011 The single-crystal X-ray structure analysis of [RuCl(2)(C(12)H(18))(C(5)H(7)NO)] reveals a distorted piano-stool geometry around the Ru(II) atom, with a hexa-methyl-benzene ligand, two chloride ligands and a furfuryl-amine ligand, the latter coordinating through the amine group. Carbon 50-51 hexosaminidase subunit alpha Homo sapiens 153-157 27186686-0 2016 Prediction of powdered activated carbon doses for 2-MIB removal in drinking water treatment using a simplified HSDM approach. Carbon 33-39 MIB E3 ubiquitin protein ligase 1 Homo sapiens 52-55 27186686-1 2016 The addition of powdered activated carbon (PAC) is an effective measure to cope with seasonal taste and odor (T&O) problems caused by 2-methylisoborneol (2-MIB) and trans-1, 10-dimethyl-trans-9-decalol (geosmin) in drinking water. Carbon 35-41 MIB E3 ubiquitin protein ligase 1 Homo sapiens 160-163 22219839-1 2011 The Ru(II) atom in the title compound, [RuCl(2)(C(12)H(18))(C(9)H(12)ClN(3)O)] CHCl(3), exhibits a typical piano-stool coordination, defined by a hexa-methyl-benzene ligand, two chloride ligands and a pyridyl-urea ligand coordinated through the pyridine N atom. Carbon 42-43 hexosaminidase subunit alpha Homo sapiens 146-150 27345161-0 2016 TOR Signaling Promotes Accumulation of BZR1 to Balance Growth with Carbon Availability in Arabidopsis. Carbon 67-73 Brassinosteroid signaling positive regulator (BZR1) family protein Arabidopsis thaliana 39-43 30317699-7 2019 Interestingly, defects in TK activity could be partially compensated by supplementation of the medium with sugar, and this effect resulted from both the availability of a carbon source and the activation of the nucleotide de novo synthesis pathway, providing evidence for a compensation mechanism between two routes of nucleotide biosynthesis that depend on nutrient availability. Carbon 171-177 Thymidine kinase Arabidopsis thaliana 26-28 21312308-6 2011 In contrast with labeling by [(13) C(6) ]-D-glucose, which produced doublets of carboxylic/amide carbons with a J coupling constant of 51 Hz, the simultaneously detected glutamate and glutamine singlets were labeled by [1-(13) C]ethanol. Carbon 97-104 complement C6 Rattus norvegicus 35-39 30520205-4 2019 Further physical characterization and density functional theory computations reveal that single Pt atoms anchored stably by four carbon atoms in carbon divacancies (Pt-C4 ) are the main active centers for the observed high ORR performance. Carbon 129-135 pericentriolar material 1 Homo sapiens 165-170 30520205-4 2019 Further physical characterization and density functional theory computations reveal that single Pt atoms anchored stably by four carbon atoms in carbon divacancies (Pt-C4 ) are the main active centers for the observed high ORR performance. Carbon 145-151 pericentriolar material 1 Homo sapiens 165-170 30669433-6 2019 The docking showed that the distance between the carbon atom of the exocyclic methylene group and the sulfur atom in Cys39 of the ZAP-70 tandem SH2 module was 3.04-5.3 A for active compounds. Carbon 49-55 zeta chain of T cell receptor associated protein kinase 70 Homo sapiens 130-136 27345161-9 2016 Such regulation of BZR1 accumulation by glucose-TOR signaling allows carbon availability to control the growth promotion hormonal programs, ensuring supply-demand balance in plant growth. Carbon 69-75 Brassinosteroid signaling positive regulator (BZR1) family protein Arabidopsis thaliana 19-23 27399788-1 2016 This study assessed the issue of membrane fouling in a Hybrid Membrane Process (HMP) due to the export of powdered activated carbon (PAC) fines from a pretreatment contactor. Carbon 125-131 inner membrane mitochondrial protein Homo sapiens 80-83 22128120-1 2011 In the late 1960s, a vibrant new research field was ignited by the discovery that instead of fixing CO(2) into a C(3) compound, some plants initially fix CO(2) into a four-carbon (C(4)) compound. Carbon 172-178 complement C4A (Rodgers blood group) Homo sapiens 180-184 27419582-0 2016 Nonvortical Rashba Spin Structure on a Surface with C_{1h} Symmetry. Carbon 52-54 spindlin 1 Homo sapiens 19-23 27419582-4 2016 This novel nonvortical RB spin structure is confirmed as a general phenomenon originating from the C_{1h} symmetry of the surface. Carbon 99-101 spindlin 1 Homo sapiens 26-30 30114588-5 2019 Among various metal ions, calcium (Ca(II)) demonstrated dramatic effects on Pb(II) removal ability of AC, while it had no effect on Pb(II) adsorption by metal oxides. Carbon 102-104 carbonic anhydrase 2 Homo sapiens 35-41 30411752-0 2019 A conjugated carbon-dot-tyrosinase bioprobe for highly selective and sensitive detection of dopamine. Carbon 13-19 tyrosinase Homo sapiens 24-34 21816602-0 2011 Artificial antibodies for troponin T by its imprinting on the surface of multiwalled carbon nanotubes: its use as sensory surfaces. Carbon 85-91 troponin T1, slow skeletal type Homo sapiens 26-36 27125576-3 2016 An electrode composed of Co-HNP on a carbon cloth (CC) produces cathodic current densities of 10 and 100 mA cm(-2) at overpotentials of -85 mV and -237 mV, respectively. Carbon 37-43 kallikrein related peptidase 8 Homo sapiens 28-31 30099315-1 2019 A fluorescent composite consisting of an ordered mesoporous material (MCM-41) and carbon quantum dots (CQDs) was successfully prepared and designated as MCM/CQDs. Carbon 82-88 methylmalonyl-CoA mutase Homo sapiens 153-156 21816602-1 2011 A novel artificial antibody for troponin T (TnT) was synthesized by molecular imprint (MI) on the surface of multiwalled carbon nanotubes (MWCNT). Carbon 121-127 troponin T1, slow skeletal type Homo sapiens 32-42 27184763-3 2016 Both novel and known locus-specific DNA-protein interactions were identified at the ENO2 and GAL1 promoter regions of Saccharomyces cerevisiae, and revealed subgroups of proteins present in significantly different levels at the loci in cells grown on glucose versus galactose as the carbon source. Carbon 283-289 phosphopyruvate hydratase ENO2 Saccharomyces cerevisiae S288C 84-88 21816602-1 2011 A novel artificial antibody for troponin T (TnT) was synthesized by molecular imprint (MI) on the surface of multiwalled carbon nanotubes (MWCNT). Carbon 121-127 troponin T1, slow skeletal type Homo sapiens 44-47 21398620-10 2011 We hypothesized that pulmonary exposure to multiwall carbon nanoparticles would induce granulomas, elicit a macrophage and T-cell response, and mimic other granulomatous disorders with an up-regulation of osteopontin. Carbon 53-59 secreted phosphoprotein 1 Homo sapiens 205-216 27208257-1 2016 Kinetically improved diacylglycerol acyltransferase (DGAT) variants were created to favorably alter carbon partitioning in soybean (Glycine max) seeds. Carbon 100-106 diacylglycerol O-acyltransferase 1A Glycine max 21-51 27208257-1 2016 Kinetically improved diacylglycerol acyltransferase (DGAT) variants were created to favorably alter carbon partitioning in soybean (Glycine max) seeds. Carbon 100-106 diacylglycerol O-acyltransferase 1A Glycine max 53-57 30472239-0 2019 Stabilization of d-lactate dehydrogenase diagnostic enzyme via immobilization on pristine and carboxyl-functionalized carbon nanotubes, a combined experimental and molecular dynamics simulation study. Carbon 118-124 lactate dehydrogenase D Homo sapiens 17-40 31902858-2 2019 Folate and vitamin B12 are key elements of the one-carbon metabolism pathway where methylenetetrahydrofolate reductase (MTHFR) plays a significant role. Carbon 51-57 methylenetetrahydrofolate reductase Homo sapiens 83-118 31902858-2 2019 Folate and vitamin B12 are key elements of the one-carbon metabolism pathway where methylenetetrahydrofolate reductase (MTHFR) plays a significant role. Carbon 51-57 methylenetetrahydrofolate reductase Homo sapiens 120-125 21782973-6 2011 Most interestingly, when oleic acid serves as the carbon source the ratio of triacylglycerol accumulation in mutants to wild-type is significantly increased in strains defective in DGA1 but not in lro1Delta. Carbon 50-56 diacylglycerol O-acyltransferase Saccharomyces cerevisiae S288C 181-185 30383323-2 2018 Structurally, they can be described as hybrids of terpenoids, amino acids, and saccharides, and share a characteristic highly strained anti-syn-anti-fused perhydrophenanthrene terpenoid scaffold (ABC-ring system) with two quaternary asymmetric carbon atoms. Carbon 244-250 synemin Homo sapiens 140-143 27118840-6 2016 Instead, the metabolic effects of GLUD2 center on the tricarboxylic acid cycle, suggesting that GLUD2 affects carbon flux during early brain development, possibly supporting lipid biosynthesis. Carbon 110-116 glutamate dehydrogenase 2 Homo sapiens 96-101 27153534-4 2016 Phosphorylation of these enzymes leads to enhanced HK activity to sustain glucose uptake but reduced activity of FBP1 to block the gluconeogenic route and reduced activity of PFK1 and ENO1 to moderate drop of glucose-6-phosphate and to repartition more carbon flux to pentose phosphate pathway (PPP), maintaining cellular energy and redox homeostasis at cellular and organismal levels. Carbon 253-259 fructose-bisphosphatase 1 Homo sapiens 113-117 21775820-3 2011 In a cell-free system, C-1311 prevented HIF-1alpha binding to an oligonucleotide encompassing a canonical hypoxia-responsive element (HRE), but did not directly interfere with HIF-1alpha protein. Carbon 23-24 hypoxia inducible factor 1, alpha subunit Mus musculus 40-50 27064509-3 2016 The addition of CrCl3 to 1-Cr, and FeCl3 to 2-Fe, afforded oxidatively triggered C-C bond formation as rac-2,2"-di(2,6-(i)Pr2C6H3N )2dicyclohexane (EA2) was produced in modest yields. Carbon 16-17 calcium voltage-gated channel subunit alpha1 A Homo sapiens 148-151 27064509-3 2016 The addition of CrCl3 to 1-Cr, and FeCl3 to 2-Fe, afforded oxidatively triggered C-C bond formation as rac-2,2"-di(2,6-(i)Pr2C6H3N )2dicyclohexane (EA2) was produced in modest yields. Carbon 18-19 calcium voltage-gated channel subunit alpha1 A Homo sapiens 148-151 26344107-2 2016 SCD1 introduces a cis-double bond at the Delta9 position (between carbons 9 and 10) of stearoyl (C18:0) and palmitoyl-CoA (C16:0). Carbon 66-73 stearoyl-CoA desaturase Homo sapiens 0-4 30446437-0 2018 Structural development of non-secosteroidal vitamin D receptor (VDR) ligands without any asymmetric carbon. Carbon 100-106 vitamin D receptor Homo sapiens 64-67 21840551-0 2011 A 400-year record of black carbon flux in the Xisha archipelago, South China Sea and its implication. Carbon 27-33 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 77-80 30451490-10 2018 These CuS NPl-carbon nanocatalysts provide inspiration for creating well-controlled layered nanomaterials for electrochemical applications and open up opportunities to design new electrocatalysts using transition-metal sulfides. Carbon 14-20 N-acetylneuraminate pyruvate lyase Homo sapiens 10-13 26254681-0 2016 Radiosensitivity of Patient-Derived Glioma Stem Cell 3-Dimensional Cultures to Photon, Proton, and Carbon Irradiation. Carbon 99-105 carboxyl ester lipase pseudogene Homo sapiens 48-54 21751327-0 2011 Synthesis, kinetic evaluation and cell-based analysis of C-alkylated isofagomines as chaperones of beta-glucocerebrosidase. Carbon 57-58 glucosylceramidase beta Homo sapiens 99-122 26962172-1 2016 G protein-coupled receptor 84 (GPR84) is a free fatty acid receptor activated by medium-chain free fatty acids with 9-14 carbons. Carbon 121-128 G protein-coupled receptor 84 Homo sapiens 0-29 26962172-1 2016 G protein-coupled receptor 84 (GPR84) is a free fatty acid receptor activated by medium-chain free fatty acids with 9-14 carbons. Carbon 121-128 G protein-coupled receptor 84 Homo sapiens 31-36 29981970-0 2018 Black carbon particles and ozone-oxidized black carbon particles induced lung damage in mice through an interleukin-33 dependent pathway. Carbon 6-12 interleukin 33 Mus musculus 104-118 29981970-0 2018 Black carbon particles and ozone-oxidized black carbon particles induced lung damage in mice through an interleukin-33 dependent pathway. Carbon 48-54 interleukin 33 Mus musculus 104-118 21486309-2 2011 Plants using the C(4) pathway of carbon metabolism are marked by greater photosynthetic water and nitrogen-use efficiencies (PWUE and PNUE, respectively) than C(3) species, but it is unclear to what extent this is the case in C(3) -C(4) intermediate species. Carbon 33-39 complement C4A (Rodgers blood group) Homo sapiens 17-21 30406794-0 2018 Carbon-encapsulated multi-phase nanocomposite of W2C@WC1-x as a highly active and stable electrocatalyst for hydrogen generation. Carbon 0-6 ATPase copper transporting beta Homo sapiens 53-56 30406794-4 2018 Subsequent heat treatment facilitates the desired phase transition of WC1-x to W2C without the formation of any secondary phases, maintaining the initial particle size and simultaneously eliminating excess amorphous carbon adhered to the nanoparticles. Carbon 216-222 ATPase copper transporting beta Homo sapiens 70-73 30662755-3 2018 Thus, in this paper, activated carbon was used to simulate the adsorption of AOX by sediments. Carbon 31-37 acyl-CoA oxidase 1 Homo sapiens 77-80 27016434-3 2016 The obtained detection and quantification limits suggest that the in-situ antimony film electrode prepared from carbon nanofibers modified screen-printed electrode (SbSPCE-CNF) produces a better analytical performance as compared to the classical SPCE modified with antimony for Pb(II) and Cd(II) determination, approving its appropriateness for measuring low mug L(-1) levels of the considered metals. Carbon 112-118 NPHS1 adhesion molecule, nephrin Homo sapiens 172-175 26736052-12 2016 Their release range was extended with increasing of heating rate and carbon content of AMFR sample. Carbon 69-75 autocrine motility factor receptor Homo sapiens 87-91 30662755-6 2018 The adsorption of activated carbon to AOX in bleaching wastewater was also studied and the optimum conditions for AOX removal were elucidated (particle size, 62 microm; time, 120 min; pH, 2.5; temperature, 40 C; and activated carbon dosage, 1.75 g l-1). Carbon 28-34 acyl-CoA oxidase 1 Homo sapiens 38-41 30662755-6 2018 The adsorption of activated carbon to AOX in bleaching wastewater was also studied and the optimum conditions for AOX removal were elucidated (particle size, 62 microm; time, 120 min; pH, 2.5; temperature, 40 C; and activated carbon dosage, 1.75 g l-1). Carbon 28-34 acyl-CoA oxidase 1 Homo sapiens 114-117 21486309-2 2011 Plants using the C(4) pathway of carbon metabolism are marked by greater photosynthetic water and nitrogen-use efficiencies (PWUE and PNUE, respectively) than C(3) species, but it is unclear to what extent this is the case in C(3) -C(4) intermediate species. Carbon 33-39 complement C4A (Rodgers blood group) Homo sapiens 232-236 30662755-7 2018 AOX adsorption by activated carbon is a chemical process. Carbon 28-34 acyl-CoA oxidase 1 Homo sapiens 0-3 30662755-9 2018 The results revealed that activated carbon exhibits a good AOX removal effect, thereby providing a theoretical basis for monitoring the AOX distribution in the environment. Carbon 36-42 acyl-CoA oxidase 1 Homo sapiens 59-62 26901756-0 2016 Hyaluronic acid modified mesoporous carbon nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells. Carbon 36-42 CD44 antigen Mus musculus 87-91 26901756-3 2016 The cellular uptake experiments of fluorescently labeled mesoporous carbon nanoparticles, with or without HA functionalization, demonstrated that HA-UMCS are able to specifically target cancer cells overexpressing CD44 receptors. Carbon 68-74 CD44 antigen Mus musculus 214-218 30662755-9 2018 The results revealed that activated carbon exhibits a good AOX removal effect, thereby providing a theoretical basis for monitoring the AOX distribution in the environment. Carbon 36-42 acyl-CoA oxidase 1 Homo sapiens 136-139 26528809-3 2016 Efficient direct electron transfer was successfully achieved for glucose oxidase (GOx) immobilized on the TiO2 NSA/carbon cloth, which produces a stable, mediator-free glucose sensor with good selectivity, high-sensitivity (52 muA mM(-1)cm(-2)), low response time (<5s) and low detection limit (23.4 muM, S/N=3). Carbon 115-121 hydroxyacid oxidase 1 Homo sapiens 65-80 26528809-3 2016 Efficient direct electron transfer was successfully achieved for glucose oxidase (GOx) immobilized on the TiO2 NSA/carbon cloth, which produces a stable, mediator-free glucose sensor with good selectivity, high-sensitivity (52 muA mM(-1)cm(-2)), low response time (<5s) and low detection limit (23.4 muM, S/N=3). Carbon 115-121 hydroxyacid oxidase 1 Homo sapiens 82-85 21707647-7 2011 By contrast, a major role of carbon balance was supported by hyponastic growth of pgm, as well as morphological, physiological (photosynthesis, sugar and starch contents) and transcriptional data. Carbon 29-35 phosphoglycerate/bisphosphoglycerate mutase Arabidopsis thaliana 82-85 26778500-1 2016 Parallel studies on organic and elemental carbon in PM1 and PM2.5 aerosols and in wet deposition in various forms of its occurrence were conducted in the urbanised coastal zone of the Baltic Sea. Carbon 42-48 transmembrane protein 11 Homo sapiens 52-55 27065422-2 2016 The possible applications of SHF are as a fuel, as a soil amendment, or for emerging applications (e.g., activated carbon precursor and odor control), depending on the charring conditions. Carbon 115-121 Src homology 2 domain containing F Homo sapiens 29-32 30961264-2 2018 The Co-GHCP could be transformed into cobalt-doped porous carbon nanosheets (Co-GPC) through direct pyrolysis treatment. Carbon 58-64 glycophorin C (Gerbich blood group) Homo sapiens 80-83 21768351-9 2011 This finding suggests a possible link between protein phosphorylation by STN8 and fine-tuning of cyclic electron flow during this critical step of photosynthesis, when the carbon assimilation is not commensurate to the electron flow capacity of the chloroplast. Carbon 172-178 Protein kinase superfamily protein Arabidopsis thaliana 73-77 30733795-2 2018 Generally, squalene synthase (SQS) is defined as an emerging and essential branch point enzyme far from the major pathway of isoprenoids biosynthetic and a latent adjusting point, which manages carbon flux into triterpenes biosynthesis and sterols. Carbon 194-200 squalene synthase 1 Arabidopsis thaliana 11-28 30733795-2 2018 Generally, squalene synthase (SQS) is defined as an emerging and essential branch point enzyme far from the major pathway of isoprenoids biosynthetic and a latent adjusting point, which manages carbon flux into triterpenes biosynthesis and sterols. Carbon 194-200 squalene synthase 1 Arabidopsis thaliana 30-33 26677131-1 2016 A well-dispersed Co,N co-doped carbon nanoframework (Co,N-CNF) with hierarchically porous structure is successfully synthesized from zeolitic imidazolate framework (ZIF) precursors via a mesoporous-silica-protected calcination strategy. Carbon 31-37 NPHS1 adhesion molecule, nephrin Homo sapiens 58-61 26787258-1 2016 The nucleophilic carbon of d(0) Schrock alkylidene metathesis catalysts, [M] = CHR, display surprisingly low downfield chemical shift (delta(iso)) and large chemical shift anisotropy. Carbon 17-23 chromate resistance; sulfate transport Homo sapiens 79-82 21767181-6 2011 RESULTS: A linear response was observed between dose and optical response between 0 Gy and 100 Gy for gamma-radiation from Co-60 and for carbon ions (both plateau and SOBP) from 0 to 20 Gy. Carbon 137-143 sine oculis binding protein homolog Homo sapiens 167-171 26784023-5 2016 Electrochemical measurements demonstrate that the PtCuNi/CNF@CF possesses superior intrinsic activity as well as mass-specific activity in comparison with the state-of-the-art Pt/C catalysts, both in acidic and alkaline solutions. Carbon 52-53 NPHS1 adhesion molecule, nephrin Homo sapiens 57-60 26661117-4 2016 Herein, we report on the synthesis of Cs[E3 C2 (trip)2 ] (1 a: E=P; 1 b: E=As; trip=2,4,6-triisopropylphenyl) and Cs[E4 C(trip)] (2 a: E=P; 2 b: E=As). Carbon 38-39 mediator complex subunit 1 Homo sapiens 44-54 26503005-4 2016 This strain could use BDE-209 as the sole carbon and energy source and degrade 65.1% of BDE-209 (initial concentration being 50 mg/L) within 144 h. To explore the BDE-209 degradation properties of this strain with the co-existed electronic donor, zerovalent iron/activated carbon (ZVI/AC) was introduced to build a microbial-chemical coupling system, which was found to promote the degradation of BDE-209 slightly (74.7% in 144 h). Carbon 42-48 homeobox D13 Homo sapiens 22-25 26503005-4 2016 This strain could use BDE-209 as the sole carbon and energy source and degrade 65.1% of BDE-209 (initial concentration being 50 mg/L) within 144 h. To explore the BDE-209 degradation properties of this strain with the co-existed electronic donor, zerovalent iron/activated carbon (ZVI/AC) was introduced to build a microbial-chemical coupling system, which was found to promote the degradation of BDE-209 slightly (74.7% in 144 h). Carbon 273-279 homeobox D13 Homo sapiens 88-91 26503005-4 2016 This strain could use BDE-209 as the sole carbon and energy source and degrade 65.1% of BDE-209 (initial concentration being 50 mg/L) within 144 h. To explore the BDE-209 degradation properties of this strain with the co-existed electronic donor, zerovalent iron/activated carbon (ZVI/AC) was introduced to build a microbial-chemical coupling system, which was found to promote the degradation of BDE-209 slightly (74.7% in 144 h). Carbon 273-279 homeobox D13 Homo sapiens 88-91 26503005-4 2016 This strain could use BDE-209 as the sole carbon and energy source and degrade 65.1% of BDE-209 (initial concentration being 50 mg/L) within 144 h. To explore the BDE-209 degradation properties of this strain with the co-existed electronic donor, zerovalent iron/activated carbon (ZVI/AC) was introduced to build a microbial-chemical coupling system, which was found to promote the degradation of BDE-209 slightly (74.7% in 144 h). Carbon 273-279 homeobox D13 Homo sapiens 88-91 26639021-4 2016 The present method allows a single-step and regioselective formation of C(sp(3))-CF2 H and C(sp(3))-O bonds from C=C moiety in alkenes, such as hydroxydifluoromethylation, regardless of terminal or internal alkenes. Carbon 72-73 ATPase H+ transporting accessory protein 1 Homo sapiens 81-84 26824558-0 2016 Carbon Tetragons as Definitive Spin Switches in Narrow Zigzag Graphene Nanoribbons. Carbon 0-6 spindlin 1 Homo sapiens 31-35 26824558-2 2016 Here we use first-principles calculations to show that when narrow zigzag graphene nanoribbons are connected to form junctions or superlattices, properly placed square-shaped carbon tetragons not only serve as effective bundles of the two incoming spin edge channels, but also act as definitive topological spin switches for the two outgoing channels. Carbon 175-181 spindlin 1 Homo sapiens 248-252 26824558-2 2016 Here we use first-principles calculations to show that when narrow zigzag graphene nanoribbons are connected to form junctions or superlattices, properly placed square-shaped carbon tetragons not only serve as effective bundles of the two incoming spin edge channels, but also act as definitive topological spin switches for the two outgoing channels. Carbon 175-181 spindlin 1 Homo sapiens 307-311 26515811-0 2016 Changes in Ocean Heat, Carbon Content, and Ventilation: A Review of the First Decade of GO-SHIP Global Repeat Hydrography. Carbon 23-29 inositol polyphosphate-5-phosphatase D Homo sapiens 91-95 26759827-1 2016 Among 272 patients undergoing a screening colonoscopy, DNA methylation of DNMT3B and MTHFR, genes encoding enzymes critical to one-carbon metabolism, was quantified in blood leukocytes using Sequenom EpiTYPER . Carbon 131-137 methylenetetrahydrofolate reductase Homo sapiens 85-90 26594240-13 2015 We performed pyruvate-feeding treatment with the newly developed Syn-YQ4 strain, and confirmed that improvement of pyruvate supply would direct more carbon flow to ethanol formation. Carbon 149-155 synemin Homo sapiens 65-68 26523465-1 2015 Substitution of the xanthene scaffold with bulky groups at C-3" and C-7" is expected to protect the electrophilic central methine carbon against nucleophilic attack and inhibit stacking. Carbon 130-136 complement C3 Homo sapiens 59-62 26523465-1 2015 Substitution of the xanthene scaffold with bulky groups at C-3" and C-7" is expected to protect the electrophilic central methine carbon against nucleophilic attack and inhibit stacking. Carbon 130-136 complement C7 Homo sapiens 68-71 26481663-0 2015 PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth. Carbon 44-50 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 0-5 26474177-3 2015 Experimental and theoretical investigations suggest that the unusual catalytic performance of this catalyst is due to sp-d orbital charge transfer between the Ni dopants and the surrounding carbon atoms. Carbon 190-196 surfactant protein D Homo sapiens 118-122 26491888-0 2015 Bimodal Latex Effect on Spin-Coated Thin Conductive Polymer-Single-Walled Carbon Nanotube Layers. Carbon 74-80 spindlin 1 Homo sapiens 24-28 26503048-5 2015 Here we describe the rhodium-catalysed carboamination of alkenes at the same (syn) face of a double bond, initiated by a carbon-hydrogen activation event that uses enoxyphthalimides as the source of both the carbon and the nitrogen functionalities. Carbon 121-127 synemin Homo sapiens 78-81 26503048-5 2015 Here we describe the rhodium-catalysed carboamination of alkenes at the same (syn) face of a double bond, initiated by a carbon-hydrogen activation event that uses enoxyphthalimides as the source of both the carbon and the nitrogen functionalities. Carbon 208-214 synemin Homo sapiens 78-81 25807359-0 2015 Role of signal transducer and activator of transcription 1 in murine allergen-induced airway remodeling and exacerbation by carbon nanotubes. Carbon 124-130 signal transducer and activator of transcription 1 Mus musculus 8-58 26188334-9 2015 Stimulation of the opening of the non-selective pore in mitochondria correlated with CNP release from mitochondria in parallel with release of cytochrome c, AIF and Endo G. Carbon 42-43 apoptosis inducing factor, mitochondria associated 1 Rattus norvegicus 157-160 32264588-7 2015 Glucose-induced decomposition of the film can be rationalized based on the scission of the carbon-boron bonds of PBA in the film by hydrogen peroxide (H2O2), which is produced through a GOx-catalyzed oxidation reaction of glucose. Carbon 91-97 hydroxyacid oxidase 1 Homo sapiens 186-189 26310518-7 2015 Due to the synergistic effect derived from TiO2 nanoparticles and carbon fibers, the obtained peapod-like TiO2 /carbon cannot only deliver a high specific capacity of 160 mAh g(-1) over 500 cycles in LIBs, but also perform a much faster photodegradation rate than bare TiO2 and P25. Carbon 112-118 tubulin polymerization promoting protein Homo sapiens 278-281 26269598-1 2015 Phosphoenolpyruvate carboxykinase (PEPCK) is one of the pivotal enzymes that regulates the carbon flow of the central metabolism by fixing CO2 to phosphoenolpyruvate (PEP) to produce oxaloacetate or vice versa. Carbon 91-97 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 35-40 26332921-8 2015 Concomitant with the reduction in nN pi* delocalization energy, the sp(2) hybrid orbital of the carbonyl carbon becomes richer in p-character, suggesting the syn configuration causes the carbonyl carbon hybrid orbitals to adopt a geometry reminiscent of a tetrahedral-like intermediate. Carbon 98-104 synemin Homo sapiens 160-163 26332921-8 2015 Concomitant with the reduction in nN pi* delocalization energy, the sp(2) hybrid orbital of the carbonyl carbon becomes richer in p-character, suggesting the syn configuration causes the carbonyl carbon hybrid orbitals to adopt a geometry reminiscent of a tetrahedral-like intermediate. Carbon 107-113 synemin Homo sapiens 160-163 26255824-2 2015 In this work, a CNF modified glassy carbon (GC) electrode that was coated with Nafion polymer was evaluated as a new electrode material for the simultaneous determination of trace levels of heavy metal ions by anodic stripping voltammetry (ASV). Carbon 36-42 NPHS1 adhesion molecule, nephrin Homo sapiens 16-19 25640045-4 2015 In order to comprehensively understand how the hydratases are able to catalyse the water addition to carbon-carbon double bonds, this review will highlight the mechanistic and stereochemical studies of the enzymatic water addition to carbon-carbon double bonds, focusing on the syn/anti-addition and stereochemistry of the reaction. Carbon 101-107 synemin Homo sapiens 278-281 25640045-4 2015 In order to comprehensively understand how the hydratases are able to catalyse the water addition to carbon-carbon double bonds, this review will highlight the mechanistic and stereochemical studies of the enzymatic water addition to carbon-carbon double bonds, focusing on the syn/anti-addition and stereochemistry of the reaction. Carbon 108-114 synemin Homo sapiens 278-281 25640045-4 2015 In order to comprehensively understand how the hydratases are able to catalyse the water addition to carbon-carbon double bonds, this review will highlight the mechanistic and stereochemical studies of the enzymatic water addition to carbon-carbon double bonds, focusing on the syn/anti-addition and stereochemistry of the reaction. Carbon 108-114 synemin Homo sapiens 278-281 25640045-4 2015 In order to comprehensively understand how the hydratases are able to catalyse the water addition to carbon-carbon double bonds, this review will highlight the mechanistic and stereochemical studies of the enzymatic water addition to carbon-carbon double bonds, focusing on the syn/anti-addition and stereochemistry of the reaction. Carbon 108-114 synemin Homo sapiens 278-281 25940489-8 2015 Special attention has been given to variations in organic carbon levels since it accounted for about one third of the total PM1 mass. Carbon 58-64 transmembrane protein 11 Homo sapiens 124-127 26279033-0 2015 Carbon-Ion Irradiation Suppresses Migration and Invasiveness of Human Pancreatic Carcinoma Cells MIAPaCa-2 via Rac1 and RhoA Degradation. Carbon 0-6 Rac family small GTPase 1 Homo sapiens 111-115 26279033-4 2015 RESULTS: Carbon-ion irradiation reduced the levels of GTP-bound Rac1 and RhoA, 2 major regulators of cell motility, in MIAPaCa-2 cells and GTP-bound Rac1 in AsPC-1 and BxPC-3 cells. Carbon 9-15 Rac family small GTPase 1 Homo sapiens 64-68 26279033-4 2015 RESULTS: Carbon-ion irradiation reduced the levels of GTP-bound Rac1 and RhoA, 2 major regulators of cell motility, in MIAPaCa-2 cells and GTP-bound Rac1 in AsPC-1 and BxPC-3 cells. Carbon 9-15 Rac family small GTPase 1 Homo sapiens 149-153 25911403-1 2015 An algorithm was developed of a treatment planning system (TPS) kernel for carbon radiotherapy in which Katz"s Track Structure Theory of cellular survival (TST) is applied as its radiobiology component. Carbon 75-81 thiosulfate sulfurtransferase Cricetulus griseus 156-159 26233252-8 2015 The proposed AF4 system can be applied to organic matter in freshwater samples having low concentration range (0.3-2.5ppm of total organic carbon) without a pre-concentration procedure. Carbon 139-145 AF4/FMR2 family member 1 Homo sapiens 13-16 26098370-6 2015 SCD1 is an integral membrane protein located in the endoplasmic reticulum, and catalyses the formation of a cis-double bond between the ninth and tenth carbons of stearoyl- or palmitoyl-CoA. Carbon 152-159 stearoyl-CoA desaturase Homo sapiens 0-4 30293059-5 2018 Proliferating T-cells and Jurkat cells also showed a greater capacity to desaturate 18-carbon PUFA substrates. Carbon 87-93 pumilio RNA binding family member 3 Homo sapiens 94-98 30453588-1 2018 More and more countries employ the Carbon Cap and Trade mechanism (CCT-mechanism) to stimulate the manufacturer to produce much more eco-friendly products. Carbon 35-41 CCT Homo sapiens 67-70 30445706-0 2018 Electrochemical Determination of beta-Lactoglobulin Employing a Polystyrene Bead-Modified Carbon Nanotube Ink. Carbon 90-96 beta-lactoglobulin Bos taurus 33-51 30445706-1 2018 In this article, we introduce the use of a carboxy-functionalized waterborne carbon nanotube ink for the fabrication of an amperometric biosensor aimed at the quantification of beta-lactoglobulin. Carbon 77-83 beta-lactoglobulin Bos taurus 177-195 30445706-6 2018 These antibody-immobilized carbon nanotube electrodes allowed for the detection of beta-lactoglobulin in sub-ppm concentrations. Carbon 27-33 beta-lactoglobulin Bos taurus 83-101 30397195-1 2018 Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme for the critical process of one-carbon metabolism involving folate and homocysteine metabolisms. Carbon 92-98 methylenetetrahydrofolate reductase Homo sapiens 0-35 30397195-1 2018 Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme for the critical process of one-carbon metabolism involving folate and homocysteine metabolisms. Carbon 92-98 methylenetetrahydrofolate reductase Homo sapiens 37-42 30063922-1 2018 BACKGROUND & AIMS: The enzyme stearoyl-coenzyme A desaturase 1 (SCD or SCD1) produces monounsaturated fatty acids by introducing double bonds into saturated bonds between carbons 9 and 10, with oleic acid as the main product. Carbon 175-182 stearoyl-Coenzyme A desaturase 1 Mus musculus 34-66 30063922-1 2018 BACKGROUND & AIMS: The enzyme stearoyl-coenzyme A desaturase 1 (SCD or SCD1) produces monounsaturated fatty acids by introducing double bonds into saturated bonds between carbons 9 and 10, with oleic acid as the main product. Carbon 175-182 stearoyl-Coenzyme A desaturase 1 Mus musculus 68-71 30063922-1 2018 BACKGROUND & AIMS: The enzyme stearoyl-coenzyme A desaturase 1 (SCD or SCD1) produces monounsaturated fatty acids by introducing double bonds into saturated bonds between carbons 9 and 10, with oleic acid as the main product. Carbon 175-182 stearoyl-Coenzyme A desaturase 1 Mus musculus 75-79 30260623-0 2018 Electrically Controllable Single-Point Covalent Functionalization of Spin-Cast Carbon-Nanotube Field-Effect Transistor Arrays. Carbon 79-85 spindlin 1 Homo sapiens 69-73 30341285-4 2018 In this study we demonstrated, for the first time, that both Euro 4 and Euro 5 carbon particles, deprived of PAHs possibly adsorbed on the soot surface, were able to: (1) significantly affect cell viability, inducing autophagy, apoptosis and necrosis; (2) stimulate the release of the pro-inflammatory cytokine IL-18; (3) elicit protein citrullination and PAD activity in NHBE cells. Carbon 79-85 interleukin 18 Homo sapiens 311-316 30229622-0 2018 [Spatial Variation of Soil Organic Carbon and Stable Isotopes in Different Soil Types of a Typical Oasis]. Carbon 35-41 cAMP responsive element binding protein 3 like 1 Homo sapiens 99-104 30279533-1 2018 Pyruvate (PYR) dehydrogenase complex (PDC) is an enzymatic system that plays a crucial role in cellular metabolism as it controls the entry of carbon into the Krebs cycle. Carbon 143-149 phosducin Homo sapiens 38-41 30040045-6 2018 Expression of Mel-CAM and L1-CAM was upregulated after low-dose photon exposure, but decreased with dose, especially after carbon-ion treatment. Carbon 123-129 calmodulin 2 Mus musculus 18-21 30839717-0 2018 Removal of Cr6+ ions from water by electrosorption on modified activated carbon fibre felt. Carbon 73-79 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 11-14 30839717-3 2018 Here, we evaluated a novel adsorbent material, activated carbon fibre felt (ACFF), for electrosorption of chromium ions (Cr6+) in sewage treatment. Carbon 57-63 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 121-124 29923239-5 2018 For complexes with an intermediate number of carbon atoms in the side chains (C10 ), both a lamellar phase at lower temperatures and a Colh phase at higher temperatures were evidenced. Carbon 45-51 chromosome 12 open reading frame 57 Homo sapiens 78-81 30102044-2 2018 Electron paramagnetic resonance spectra of the spin adduct and the adduct formed in the analogous reaction with selectively deuterated substrate identify the radical intermediate in this SmI2 reduction as a carbon-centered radical. Carbon 207-213 spindlin 1 Homo sapiens 47-51 30101423-2 2018 Herein, a new bifunctional cathode substrate configured with boron-carbide nanowires in situ grown on carbon nanofibers (B4 C@CNF) is established through a facile catalyst-assisted process. Carbon 102-108 NPHS1 adhesion molecule, nephrin Homo sapiens 126-129 29959734-0 2018 Equilibrium adsorption study of the adsorptive removal of Cd2+ and Cr6+ using activated carbon. Carbon 88-94 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 67-70 29959734-3 2018 The adsorption isotherms of Cd2+ and Cr6+ on activated carbon can fit the Langmuir model well, and correlation coefficients were above 0.99, all higher than the Freundlich and Temkin models. Carbon 55-61 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 37-40 29959734-8 2018 The speciation on activated carbon was mainly residual Cd2+ and Cr6+, and the potential ecological risk of Cd2+ is higher than that of Cr6+. Carbon 28-34 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 64-67 29959734-8 2018 The speciation on activated carbon was mainly residual Cd2+ and Cr6+, and the potential ecological risk of Cd2+ is higher than that of Cr6+. Carbon 28-34 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 135-138 29959734-9 2018 The adsorptions of Cd2+ and Cr6+ on activated carbon were dominated by chelation and ion exchange, respectively. Carbon 46-52 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 28-31 30114676-6 2018 This study showed that increased carbon levels in transgenic rice lines overexpressing C4-PEPC could help regulate the photorespiratory pathway under low-N conditions, conferring low-N tolerance and a higher grain yield per plant. Carbon 33-39 phosphoenolpyruvate carboxylase 1 Zea mays 90-94 29631090-0 2018 Mercury bonds with carbon (OC and EC) in small aerosols (PM1) in the urbanized coastal zone of the Gulf of Gdansk (southern Baltic). Carbon 19-25 transmembrane protein 11 Homo sapiens 57-60 29631090-0 2018 Mercury bonds with carbon (OC and EC) in small aerosols (PM1) in the urbanized coastal zone of the Gulf of Gdansk (southern Baltic). Carbon 34-36 transmembrane protein 11 Homo sapiens 57-60 29631090-2 2018 The main purpose of the study was to determine the variability in concentrations of mercury Hg(p), organic carbon (OC) and elemental carbon (EC) in PM1 aerosols under varying synoptic conditions in heating and non-heating periods. Carbon 133-139 transmembrane protein 11 Homo sapiens 148-151 29631090-2 2018 The main purpose of the study was to determine the variability in concentrations of mercury Hg(p), organic carbon (OC) and elemental carbon (EC) in PM1 aerosols under varying synoptic conditions in heating and non-heating periods. Carbon 141-143 transmembrane protein 11 Homo sapiens 148-151 30059121-3 2018 Accordingly, indium(iii) halides and salts (InX3, X = Cl, Br, I, OTf, ONf, NTf2) have been reported as useful catalysts for a broad range of carbon-carbon and carbon-heteroatom bond formation reactions, including hydrofunctionalization (hydroarylation, hydroamination, hydroalkoxylation, and hydrothiolation), enyne cycloisomerization, and related reactions. Carbon 141-147 nuclear transport factor 2 Homo sapiens 75-79 30059121-3 2018 Accordingly, indium(iii) halides and salts (InX3, X = Cl, Br, I, OTf, ONf, NTf2) have been reported as useful catalysts for a broad range of carbon-carbon and carbon-heteroatom bond formation reactions, including hydrofunctionalization (hydroarylation, hydroamination, hydroalkoxylation, and hydrothiolation), enyne cycloisomerization, and related reactions. Carbon 148-154 nuclear transport factor 2 Homo sapiens 75-79 30059121-3 2018 Accordingly, indium(iii) halides and salts (InX3, X = Cl, Br, I, OTf, ONf, NTf2) have been reported as useful catalysts for a broad range of carbon-carbon and carbon-heteroatom bond formation reactions, including hydrofunctionalization (hydroarylation, hydroamination, hydroalkoxylation, and hydrothiolation), enyne cycloisomerization, and related reactions. Carbon 148-154 nuclear transport factor 2 Homo sapiens 75-79 30128056-4 2018 This understanding leads to achieving thermoelectric power factors as high as 412 muW m-1 K-2 in thin carbon nanotube films. Carbon 102-108 RBPJ pseudogene 3 Homo sapiens 90-93 30008872-5 2018 Subsequently, the expression of the one-carbon metabolic enzymes methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), aldehyde dehydrogenase 1 family member L2 (ALDH1L2), and serine hydroxymethyltransferase (SHMT2) was examined using immunohistochemical analysis. Carbon 40-46 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 65-106 30008872-5 2018 Subsequently, the expression of the one-carbon metabolic enzymes methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), aldehyde dehydrogenase 1 family member L2 (ALDH1L2), and serine hydroxymethyltransferase (SHMT2) was examined using immunohistochemical analysis. Carbon 40-46 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 108-114 30008872-5 2018 Subsequently, the expression of the one-carbon metabolic enzymes methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), aldehyde dehydrogenase 1 family member L2 (ALDH1L2), and serine hydroxymethyltransferase (SHMT2) was examined using immunohistochemical analysis. Carbon 40-46 serine hydroxymethyltransferase 2 Homo sapiens 207-212 29759239-2 2018 Herein, single-hole hollow molecularly imprinted polymers embedded carbon dots (HMIP@CD) was prepared via microwave-assisted method. Carbon 67-73 mitochondrial intermediate peptidase Homo sapiens 80-84 29891549-0 2018 Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates. Carbon 53-59 glycine N-methyltransferase Mus musculus 0-27 29733595-0 2018 Water-Mediated Carbon-Oxygen Hydrogen Bonding Facilitates S-Adenosylmethionine Recognition in the Reactivation Domain of Cobalamin-Dependent Methionine Synthase. Carbon 15-21 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 121-160 29573715-6 2018 Congener group profiles analysis indicated C11- and C13-congener groups were predominant in carbon homologues of SCCPs, and C14-congener groups were predominant in MCCPs. Carbon 92-98 RNA polymerase III subunit K Homo sapiens 43-46 29578617-4 2018 EDA-NOCV calculations suggest that the carbon-carbon interactions in C2 F4 at equilibrium distance and longer C-C values up to 1.60 A are best described in terms of electron-sharing bonding between the CF2 fragments in the (3 B1 ) excited state. Carbon 39-45 ATPase H+ transporting accessory protein 1 Homo sapiens 203-206 29578617-4 2018 EDA-NOCV calculations suggest that the carbon-carbon interactions in C2 F4 at equilibrium distance and longer C-C values up to 1.60 A are best described in terms of electron-sharing bonding between the CF2 fragments in the (3 B1 ) excited state. Carbon 46-52 ATPase H+ transporting accessory protein 1 Homo sapiens 203-206 29578617-4 2018 EDA-NOCV calculations suggest that the carbon-carbon interactions in C2 F4 at equilibrium distance and longer C-C values up to 1.60 A are best described in terms of electron-sharing bonding between the CF2 fragments in the (3 B1 ) excited state. Carbon 6-7 ATPase H+ transporting accessory protein 1 Homo sapiens 203-206 30271955-2 2018 Peptidylglycine alpha-hydroxylating monooxygenase (PHM) is a dicopper enzyme that catalyzes hydroxylation of the alpha-carbon of glycine-extended peptides for the formation of des-glycine amidated peptides. Carbon 119-125 peptidylglycine alpha-amidating monooxygenase Homo sapiens 0-49 30271955-2 2018 Peptidylglycine alpha-hydroxylating monooxygenase (PHM) is a dicopper enzyme that catalyzes hydroxylation of the alpha-carbon of glycine-extended peptides for the formation of des-glycine amidated peptides. Carbon 119-125 peptidylglycine alpha-amidating monooxygenase Homo sapiens 51-54 29940994-16 2018 NS3 from RSV affects the expression of genes associated with ribosomes, photosynthesis, and carbon metabolism in N. benthamiana. Carbon 92-98 KRAS proto-oncogene, GTPase Homo sapiens 0-3 29703735-0 2018 The Catabolite Repressor/Activator Cra Is a Bridge Connecting Carbon Metabolism and Host Colonization in the Plant Drought Resistance-Promoting Bacterium Pantoea alhagi LTYR-11Z. Carbon 62-68 myotubularin related protein 11 Homo sapiens 35-38 29703735-6 2018 Consistent with previous findings that Cra plays a role in transcriptional regulation in response to carbon source availability, the activating effects of Cra were much more pronounced when LTYR-11Z was grown within a gluconeogenic environment than when it was grown within a glycolytic environment. Carbon 101-107 myotubularin related protein 11 Homo sapiens 39-42 29703735-8 2018 Altogether, these results uncover a novel strategy utilized by LTYR-11Z to achieve host colonization in response to carbon nutrition in the environment, in which Cra bridges a connection between carbon metabolism and colonization capacity of LTYR-11Z.IMPORTANCE Rapid and appropriate response to environmental signals is crucial for bacteria to adapt to competitive environments and to establish interactions with their hosts. Carbon 116-122 myotubularin related protein 11 Homo sapiens 162-165 26011743-5 2015 As crop diversity increased from one to five species, distinct soil microbial communities were related to increases in soil aggregation, organic carbon, total nitrogen, microbial activity and decreases in the carbon-to-nitrogen acquiring enzyme activity ratio. Carbon 145-151 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 3-7 26011743-5 2015 As crop diversity increased from one to five species, distinct soil microbial communities were related to increases in soil aggregation, organic carbon, total nitrogen, microbial activity and decreases in the carbon-to-nitrogen acquiring enzyme activity ratio. Carbon 209-215 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 3-7 25934105-1 2015 In the study, the electrochemical behavior of glucose oxidase (GOx) immobilized on poly([2,2";5",2""]-terthiophene-3"-carbaldehyde) (poly(TTP)) modified glassy carbon electrode (GCE) was investigated. Carbon 160-166 hydroxyacid oxidase 1 Homo sapiens 46-61 25934105-1 2015 In the study, the electrochemical behavior of glucose oxidase (GOx) immobilized on poly([2,2";5",2""]-terthiophene-3"-carbaldehyde) (poly(TTP)) modified glassy carbon electrode (GCE) was investigated. Carbon 160-166 hydroxyacid oxidase 1 Homo sapiens 63-66 25822580-4 2015 Co-stimulation with IFN-gamma and the TLR3 ligand poly (I:C) synergistically increased the expression of IFN-beta, IL-6, IL-8, and human beta-defensin-2 in NHEKs compared with poly (I:C) or IFN-gamma alone. Carbon 0-1 defensin beta 4B Homo sapiens 137-152 26079324-3 2015 All the genes showed low mean methylation levels (<5%) in both AD and control DNA, no difference between groups, and no correlation with the studied biomarkers, except for MTHFR that showed methylation levels ranging from 5% to 75%, and correlation with circulating biomarkers of one-carbon metabolism. Carbon 284-290 methylenetetrahydrofolate reductase Homo sapiens 172-177 25818356-1 2015 PdCo alloy nanoparticle-embedded carbon nanofiber (PdCo/CNF) prepared by electrospinning and thermal treatment was employed as a high-performance platform for the determination of hydrogen peroxide and nitrite. Carbon 33-39 NPHS1 adhesion molecule, nephrin Homo sapiens 56-59 29703735-8 2018 Altogether, these results uncover a novel strategy utilized by LTYR-11Z to achieve host colonization in response to carbon nutrition in the environment, in which Cra bridges a connection between carbon metabolism and colonization capacity of LTYR-11Z.IMPORTANCE Rapid and appropriate response to environmental signals is crucial for bacteria to adapt to competitive environments and to establish interactions with their hosts. Carbon 195-201 myotubularin related protein 11 Homo sapiens 162-165 29703735-11 2018 In this work, we unraveled the pivotal role of Cra in regulation of colonization ability of Pantoea alhagi LTYR-11Z in response to carbon source availability. Carbon 131-137 myotubularin related protein 11 Homo sapiens 47-50 29703735-12 2018 Moreover, we identified three novel members of the Cra regulon involved in EPS synthesis, regulation of flagellar biosynthesis, and synthesis of c-di-GMP and propose a working model to explain the Cra-mediated regulatory mechanism that links carbon metabolism to host colonization. Carbon 242-248 myotubularin related protein 11 Homo sapiens 51-54 29703735-12 2018 Moreover, we identified three novel members of the Cra regulon involved in EPS synthesis, regulation of flagellar biosynthesis, and synthesis of c-di-GMP and propose a working model to explain the Cra-mediated regulatory mechanism that links carbon metabolism to host colonization. Carbon 242-248 myotubularin related protein 11 Homo sapiens 197-200 26076355-5 2015 The expression of genes encoding integrin subunits alpha5, alphav, beta1, and beta3 was significantly upregulated at the early of time-point when cells initially attached to the carbon nanotube/polymer composite. Carbon 178-184 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 67-83 21804310-9 2011 Exposure of pregnant ICR mice to carbon black resulted in increased expression of Collagen, type VIII, a1 (Col8a1) in the tubular cells in the kidney of 12-week-old offspring mice but not in 3-week-old ones. Carbon 33-39 collagen, type VIII, alpha 1 Mus musculus 107-113 32262235-4 2015 The resulting hybrid nonmaterial allowed highly stable aqueous dispersions to be obtained, which were used to coat glassy carbon electrodes for the preparation of a model tyrosinase electrochemical biosensor for catechol. Carbon 122-128 tyrosinase Homo sapiens 171-181 21586816-1 2011 The hole transport properties of poly(2-methoxy, 5-(2"-ethyl-hexoxy)-p-phenylene vinylene) (MEH-PPV) blended with acid oxidized multiwall carbon nanotubes (COOH-MWCNTs) were investigated in a diode configuration using the time-of-flight (TOF) photocurrent method. Carbon 138-144 epoxide hydrolase 1 Homo sapiens 92-95 25675894-1 2015 BACKGROUND: Airborne fiber size has been shown to be an important factor relative to adverse lung effects of asbestos and suggested in animal studies of carbon nanotubes and nanofibers (CNT/CNF). Carbon 153-159 NPHS1 adhesion molecule, nephrin Homo sapiens 190-193 29529460-3 2018 In this study, we synthesized PAN-based carbon nanofibers (CNF) by electrospinning, and characterized them using electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, Raman spectroscopy, and thermogravimetric analysis. Carbon 40-46 NPHS1 adhesion molecule, nephrin Homo sapiens 59-62 21426427-8 2011 TPS11 also promotes the re-allocation of carbon into starch at the expense of sucrose, the primary plant-derived carbon and energy source for the insect. Carbon 41-47 trehalose phosphatase/synthase 11 Arabidopsis thaliana 0-5 25899290-8 2015 Optimizations of the TEDOR pulse scheme in the case of a quadrupolar nucleus with a small quadrupole coupling constant show that it is most efficient when pulses are positioned on the spin-1/2 (carbon-13) nucleus. Carbon 194-200 spindlin 1 Homo sapiens 184-192 26504962-1 2015 Simultaneous determination of N-acetyl-L-cysteine (NAC) and Tryptophan (Trp) has been studied at the surface of glassy carbon electrode (GCE) modified with multi-walled carbon nanotubes (MWCNTs) in the presence of 4-chlorocatechol as homogenous electrochemical catalyst in aqueous media. Carbon 119-125 X-linked Kx blood group Homo sapiens 51-54 21426427-8 2011 TPS11 also promotes the re-allocation of carbon into starch at the expense of sucrose, the primary plant-derived carbon and energy source for the insect. Carbon 113-119 trehalose phosphatase/synthase 11 Arabidopsis thaliana 0-5 21185256-0 2011 Carbon metabolism and the sign of control coefficients in metabolic adaptations underlying K-ras transformation. Carbon 0-6 Kirsten rat sarcoma viral oncogene homolog Mus musculus 91-96 25736470-8 2015 Correspondingly, both photon and carbon ion irradiation downregulate soluble MMP9 concentrations, while upregulating cell surface expression of proadhesive extracellular matrix protein-binding integrin alpha5. Carbon 33-39 matrix metallopeptidase 9 Homo sapiens 77-81 25736470-10 2015 Both photon and (even more so) carbon ion irradiation are effective in inhibiting medulloblastoma cell migration through downregulation of matrix metalloproteinase 9 and upregulation of proadhesive cell surface integrin alpha5, which lead to increased cell adherence to extracellular matrix proteins. Carbon 31-37 matrix metallopeptidase 9 Homo sapiens 139-165 21333504-2 2011 The electrochemical behaviors of caffeine on Nafion-Gr modified glassy carbon electrode (Nafion-Gr/GCE) were investigated by cyclic voltammetry and differential pulse voltammetry. Carbon 71-77 aminomethyltransferase Homo sapiens 99-102 25732624-4 2015 Simultaneous overexpression of SCD, Acetyl-CoA carboxylase (ACC1), and Diacylglyceride acyl-transferase (DGA1) in Y. lipolytica yielded an engineered strain exhibiting highly desirable phenotypes of fast cell growth and lipid overproduction including high carbon to lipid conversion yield (84.7% of theoretical maximal yield), high lipid titers (~55g/L), enhanced tolerance to glucose and cellulose-derived sugars. Carbon 256-262 stearoyl-CoA desaturase Homo sapiens 31-34 21395949-6 2011 Because of the use of part ethanol as an auxiliary carbon source, more than twice the theoretical requirement of ethanol was needed to achieve a high 2,4-DNT removal efficiency (>93%). Carbon 51-57 5', 3'-nucleotidase, cytosolic Homo sapiens 154-157 25680575-9 2015 Moreover, adiponectin concentrations in cows with C-LA greater than 45 days decreased more than those with C-LA 45 days or less after week 3 postpartum (P = 0.002). Carbon 50-51 adiponectin, C1Q and collagen domain containing Bos taurus 10-21 21232934-2 2011 Batch tests were carried out to determine the potential and the effectiveness of granular activated carbon (GAC) in removal of pesticide in agricultural run off. Carbon 100-106 glutaminase Homo sapiens 108-111 25788393-2 2015 A density of 150-200 single-walled carbon nanotubes per micro-meter is achieved with a current density of 10.08 muA mum(-1) at VDS = -1 V. The on-current density is improved by a factor of 45 over that of random-network single-walled carbon nanotubes. Carbon 35-41 PWWP domain containing 3A, DNA repair factor Homo sapiens 116-122 25995901-3 2015 The oxirane O atom and the bridging ester O atom are in an approximate syn conformation [O-C-C-O = -25.4 (3) ] In the crystal, inversion dimers linked by pair of C-H O hydrogen bonds generate R 2 (2)(8) loops, where the C-H donor group forms part of the oxirane ring. Carbon 91-92 synemin Homo sapiens 71-74 25995901-3 2015 The oxirane O atom and the bridging ester O atom are in an approximate syn conformation [O-C-C-O = -25.4 (3) ] In the crystal, inversion dimers linked by pair of C-H O hydrogen bonds generate R 2 (2)(8) loops, where the C-H donor group forms part of the oxirane ring. Carbon 93-94 synemin Homo sapiens 71-74 25461755-1 2015 A new uric acid biosensor was constructed using ferrocene (Fc) induced electro-activated uricase (UOx) deposited within Nafion (Naf) on glassy carbon electrode (GCE). Carbon 143-149 urate oxidase (pseudogene) Homo sapiens 98-101 21303221-9 2011 Proteomic analysis showed that hGSTZ1-1 was inactivated when Cys-16 was modified by glutathione and the carbon skeleton of DCA. Carbon 104-110 glutathione S-transferase zeta 1 Homo sapiens 31-39 25725609-0 2015 Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures. Carbon 118-124 lysine demethylase 1A Homo sapiens 81-85 25725609-4 2015 Here we report the design additional (bis)urea and (bis)thiourea LSD1 inhibitors that feature 3-5-3 or 3-6-3 carbon backbone architectures. Carbon 109-115 lysine demethylase 1A Homo sapiens 65-69 25672970-6 2015 Finally, we demonstrated that C-30-27 improved cognitive deficits, as well as the capacity for locomotion and the damaged cholinergic system in the Abeta-treated rats. Carbon 30-31 amyloid beta precursor protein Rattus norvegicus 148-153 21324323-1 2011 AIMS: Folate coenzymes and dependent enzymes introduce one carbon units at positions 2 (C(2)) and 8 (C(8)) of the purine ring during de novo biosynthesis. Carbon 59-65 complement C2 Homo sapiens 88-92 25826744-4 2015 Over them, high carbon yield (96.7%) of C10 and C15 oxygenates was achieved. Carbon 16-22 placenta associated 8 Homo sapiens 48-51 21467295-0 2011 ATM is a redox sensor linking genome stability and carbon metabolism. Carbon 51-57 ATM serine/threonine kinase Homo sapiens 0-3 25852419-5 2015 Glucose sensing tests were performed using printed carbon-AuNP electrodes functionalized with glucose oxidase (GOx). Carbon 51-57 hydroxyacid oxidase 1 Homo sapiens 94-109 21687356-11 2011 In(13) C- NMR spectra, C-3 and C-5 of the 1,2,4 - triazole nucleus were observed in the range of delta 147-166.9 ppm. Carbon 7-8 complement C5 Homo sapiens 31-34 25852419-5 2015 Glucose sensing tests were performed using printed carbon-AuNP electrodes functionalized with glucose oxidase (GOx). Carbon 51-57 hydroxyacid oxidase 1 Homo sapiens 111-114 21296579-4 2011 Elongation of the C-3 and C-5 carbon chains reduced activity relative to propyl substituted analogues; however, activity was still better than that of natural compound 1. Carbon 30-36 complement C5 Homo sapiens 26-29 25691733-10 2015 O2 directly regulates two transcription factors, genes linked to carbon and amino acid metabolism and abiotic stress resistance. Carbon 65-71 regulatory protein opaque-2 Zea mays 0-2 26261966-1 2015 Using density functional theory, a possible pathway of soot surface growth is studied in the low-temperature, postflame region in which spin-triplet polycyclic aromatic hydrocarbon (PAH) molecules with a small singlet-triplet energy gap react with unsaturated aliphatics such as acetylene via the carbon-addition-hydrogen-migration (CAHM) reaction. Carbon 174-180 spindlin 1 Homo sapiens 136-140 21247114-9 2011 Elevated stability and water exchange rate indicate that the presence of cyclobutyl on the carbon backbone imparts rigidity and steric constraint to [Gd(CB-TTDA)(H(2)O)](2-)and [Gd(Bz-CB-TTDA)(H(2)O)](2-). Carbon 91-97 general transcription factor IIH subunit 5 Homo sapiens 156-160 21247114-9 2011 Elevated stability and water exchange rate indicate that the presence of cyclobutyl on the carbon backbone imparts rigidity and steric constraint to [Gd(CB-TTDA)(H(2)O)](2-)and [Gd(Bz-CB-TTDA)(H(2)O)](2-). Carbon 91-97 general transcription factor IIH subunit 5 Homo sapiens 187-191 21194206-1 2011 For modeling the sorption of organic compounds in soils it is typically assumed that the organic carbon/water partitioning coefficient (Koc) of neutral organic chemicals can be treated as a constant property that remains unaffected by the type of soil organic matter as well as pH in the soil solution. Carbon 97-103 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 136-139 25533095-0 2015 Adsorption of surfactant protein D from human respiratory secretions by carbon nanotubes and polystyrene nanoparticles depends on nanomaterial surface modification and size. Carbon 72-78 surfactant protein D Homo sapiens 14-34 25483989-2 2015 The study was aimed at analyzing different working conditions and the influence of different IA cycles on the biological performance of the MBR pilot plant, in terms of organic carbon and ammonium removal as well as extracellular polymeric substances (EPSs) production. Carbon 177-183 translocator protein Homo sapiens 140-143 21106902-2 2011 Here, we used ELOVL2-ablated (Elovl2(-/-)) mice to show that the PUFAs with 24-30 carbon atoms of the omega-6 family in testis are indispensable for normal sperm formation and fertility in male mice. Carbon 82-88 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 Mus musculus 14-20 25562715-1 2015 Docosahexaenoic acid (DHA) is a 22 carbon, six cis-double bonded (22:6, w3) omega-3 polyunsaturated acid (PUFA), found highly enriched with neuronal membranes, and believed to play a critical role in synaptic plasticity and cognitive correlates of learning and memory. Carbon 35-41 pumilio RNA binding family member 3 Homo sapiens 106-110 21106902-2 2011 Here, we used ELOVL2-ablated (Elovl2(-/-)) mice to show that the PUFAs with 24-30 carbon atoms of the omega-6 family in testis are indispensable for normal sperm formation and fertility in male mice. Carbon 82-88 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 Mus musculus 30-36 21098489-4 2011 eNOS and FAS were physically associated; eNOS palmitoylation was decreased in FAS-deficient cells, and incorporation of labeled carbon into eNOS-associated palmitate was FAS-dependent. Carbon 128-134 nitric oxide synthase 3, endothelial cell Mus musculus 0-4 25612818-1 2015 We examined the biomolecular recognition ability of RecA proteins using single-walled carbon nanotubes (SWNTs) wrapped with a single-stranded DNA (ssDNA) molecule as a mimic for the usual ssDNA molecules. Carbon 86-92 RAD51 recombinase Homo sapiens 52-56 25522366-0 2015 Electronically type-sorted carbon nanotube-based electrochemical biosensors with glucose oxidase and dehydrogenase. Carbon 27-33 hydroxyacid oxidase 1 Homo sapiens 81-96 21071060-6 2011 The C2 and C3 had a direct relationship with a(CDOM)(355), dissolved organic carbon (DOC), and chemical oxygen demand (COD). Carbon 77-83 complement C2 Homo sapiens 4-13 25522366-6 2015 This indicates that direct electron transfer occurred with the semiconducting SWNT-GOx electrode, whereas the metallic SWNT-GOx electrode was dominated by a hydrogen peroxide pathway caused by an enzymatic reaction. Carbon 78-82 hydroxyacid oxidase 1 Homo sapiens 83-86 25459828-0 2015 Enhanced removal of nitrate using starch/PCL blends as solid carbon source in a constructed wetland. Carbon 61-67 PHD finger protein 1 Homo sapiens 41-44 20832258-1 2011 A gold/sodium dodecylbenzene sulfonate nanoparticles modified glassy carbon electrode (nano-Au/SDBS/GCE) was electrochemically fabricated with a constant potential at -0.4V. Carbon 69-75 aminomethyltransferase Homo sapiens 100-103 26328311-3 2015 More details of preparing PLGA-F127 NSs and immobilizing glucose oxidase (GOx) on (PLGA-F127)/glass carbon electrode (GCE) were presented. Carbon 100-106 hydroxyacid oxidase 1 Homo sapiens 57-72 26328311-3 2015 More details of preparing PLGA-F127 NSs and immobilizing glucose oxidase (GOx) on (PLGA-F127)/glass carbon electrode (GCE) were presented. Carbon 100-106 hydroxyacid oxidase 1 Homo sapiens 74-77 20737426-8 2011 Exposure to carboxylated functionalized SWCNT induced ROS and enhanced the activities of serum amino-transferases (ALT/AST) and alkaline phosphatases (ALP) and the concentration of lipid hydroperoxide compared with control. Carbon 40-45 glutamic pyruvic transaminase, soluble Mus musculus 115-118 25515537-4 2014 We determined that Npr2-deficient yeast had a metabolic state distinct from that of wild-type yeast when grown in minimal media containing ammonium as a nitrogen source and a nonfermentable carbon source (lactate). Carbon 190-196 nitrogen permease regulating protein NPR2 Saccharomyces cerevisiae S288C 19-23 25459222-1 2014 The hybrid membrane process (HMP) coupling powdered activated carbon (PAC) and low-pressure membrane filtration is emerging as a promising new option to remove dissolved contaminants from drinking water. Carbon 62-68 inner membrane mitochondrial protein Homo sapiens 29-32 21343675-0 2011 Carbon ion irradiation suppresses metastatic potential of human non-small cell lung cancer A549 cells through the phosphatidylinositol-3-kinase/Akt signaling pathway. Carbon 0-6 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Homo sapiens 114-143 21343675-1 2011 We previously showed that carbon ion irradiation can inhibit the expression of the anillin (ANLN) gene, which is regulated by the activation of the phosphatidylinositol-3-kinase (PI3K)/Akt signaling pathway associated with metastasis. Carbon 26-32 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Homo sapiens 148-177 25267444-2 2014 Prominent examples are the Schiff-base forming class I FBP and F6P aldolase as well as transaldolase, which all exploit an active center lysine to reversibly cleave the C3-C4 bond of fructose-1,6-bisphosphate or fructose-6-phosphate to give two 3-carbon products (aldolase), or to shuttle 3-carbon units between various phosphosugars (transaldolase). Carbon 247-253 transaldolase 1 Homo sapiens 87-100 20934908-4 2011 Also gamma-gauche and delta-effects of the alkyl groups at C-3 on the carbons of the aryl group at C-2 have been studied. Carbon 70-77 complement C2 Homo sapiens 99-102 25267444-2 2014 Prominent examples are the Schiff-base forming class I FBP and F6P aldolase as well as transaldolase, which all exploit an active center lysine to reversibly cleave the C3-C4 bond of fructose-1,6-bisphosphate or fructose-6-phosphate to give two 3-carbon products (aldolase), or to shuttle 3-carbon units between various phosphosugars (transaldolase). Carbon 247-253 transaldolase 1 Homo sapiens 335-348 25261840-1 2014 This article describes the adsorption of glucose oxidase (GOx) onto optically transparent carbon electrodes (OTCE) under the effect of applied potential and the analysis of the enzymatic activity of the resulting GOx/OTCE substrates. Carbon 90-96 hydroxyacid oxidase 1 Homo sapiens 41-56 21137980-0 2010 Carbon nanotubes induce secondary structure changes of bovine albumin in aqueous phase. Carbon 0-6 albumin Bos taurus 62-69 25261840-1 2014 This article describes the adsorption of glucose oxidase (GOx) onto optically transparent carbon electrodes (OTCE) under the effect of applied potential and the analysis of the enzymatic activity of the resulting GOx/OTCE substrates. Carbon 90-96 hydroxyacid oxidase 1 Homo sapiens 58-61 25261840-1 2014 This article describes the adsorption of glucose oxidase (GOx) onto optically transparent carbon electrodes (OTCE) under the effect of applied potential and the analysis of the enzymatic activity of the resulting GOx/OTCE substrates. Carbon 90-96 hydroxyacid oxidase 1 Homo sapiens 213-216 25262300-4 2014 RESULTS: For UGT1A1, we found minor allele A of rs4148323 (G211A, UGT1A1*6) contributed to higher daily bilirubin levels on days 4-6 (with contributions to variations increasing from 4.8% to 12.3%), minor allele T of rs887829 (c-364t) contributed to lower daily bilirubin levels for days 6 and 7 (with contributions to variations increasing from 7.0% to 10.2%) (P < .03 for all). Carbon 76-77 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 13-19 25262300-4 2014 RESULTS: For UGT1A1, we found minor allele A of rs4148323 (G211A, UGT1A1*6) contributed to higher daily bilirubin levels on days 4-6 (with contributions to variations increasing from 4.8% to 12.3%), minor allele T of rs887829 (c-364t) contributed to lower daily bilirubin levels for days 6 and 7 (with contributions to variations increasing from 7.0% to 10.2%) (P < .03 for all). Carbon 76-77 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 66-72 21137980-9 2010 All together, it was concluded that the oxidized water-soluble multiwalled carbon nanotubes not only adsorb bovine serum albumin molecules to their surface, but also induces albumin molecules in the aqueous solution undergo secondary structure changes, which lead to a conformation change. Carbon 75-81 albumin Bos taurus 115-128 21137980-9 2010 All together, it was concluded that the oxidized water-soluble multiwalled carbon nanotubes not only adsorb bovine serum albumin molecules to their surface, but also induces albumin molecules in the aqueous solution undergo secondary structure changes, which lead to a conformation change. Carbon 75-81 albumin Bos taurus 121-128 20638103-11 2010 Obtained results for organic and elemental carbon fluxes showed that atmospheric aerosols can be treated, along with water run-off, as a carbon source for the coastal waters of the Baltic Sea. Carbon 43-49 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 188-191 25336519-0 2014 Acclimation to very low CO2: contribution of limiting CO2 inducible proteins, LCIB and LCIA, to inorganic carbon uptake in Chlamydomonas reinhardtii. Carbon 106-112 uncharacterized protein Chlamydomonas reinhardtii 78-82 25336519-5 2014 The contrasting effects of individual mutations in LCIB and LCIA compared with the effects of LCIB-LCIA double mutations on growth and inorganic carbon-dependent photosynthetic O2 evolution reveal distinct roles of LCIA and LCIB in the CCM. Carbon 145-151 uncharacterized protein Chlamydomonas reinhardtii 94-98 25336519-5 2014 The contrasting effects of individual mutations in LCIB and LCIA compared with the effects of LCIB-LCIA double mutations on growth and inorganic carbon-dependent photosynthetic O2 evolution reveal distinct roles of LCIA and LCIB in the CCM. Carbon 145-151 uncharacterized protein Chlamydomonas reinhardtii 94-98 20638103-11 2010 Obtained results for organic and elemental carbon fluxes showed that atmospheric aerosols can be treated, along with water run-off, as a carbon source for the coastal waters of the Baltic Sea. Carbon 137-143 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 188-191 27081514-0 2014 Osteogenesis imperfecta IIC caused by a novel heterozygous mutation in the C-propeptide region of COL1A1. Carbon 26-27 collagen type I alpha 1 chain Homo sapiens 98-104 20683790-1 2010 The mechanism of transformation of two radicals (R1p and R1i) obtained by addition of a hydrogen atom to an external and internal carbon atom of dicyclopenta[de,mn]anthracene (P1) was investigated. Carbon 130-136 CD1b molecule Homo sapiens 49-52 24874657-2 2014 Here, we developed a platform based on nanovesicle-carbon nanotube hybrid nanostructures for the real-time detection of anti-AQP4 antibodies and the electrophysiological monitoring of AQP4 activities. Carbon 51-57 aquaporin 4 Homo sapiens 125-129 24874657-2 2014 Here, we developed a platform based on nanovesicle-carbon nanotube hybrid nanostructures for the real-time detection of anti-AQP4 antibodies and the electrophysiological monitoring of AQP4 activities. Carbon 51-57 aquaporin 4 Homo sapiens 184-188 24966045-0 2014 Expression and knockdown of the PEPC1 gene affect carbon flux in the biosynthesis of triacylglycerols by the green alga Chlamydomonas reinhardtii. Carbon 50-56 uncharacterized protein Chlamydomonas reinhardtii 32-37 19902353-8 2010 The full length AAT showed a consistent expression pattern as C-41/42, and C-41/42 can be generated in vitro by MMP-7 cleavage. Carbon 75-76 matrix metallopeptidase 7 Homo sapiens 112-117 24676540-4 2014 In this work, we report the experimentally observed DET of the GOx enzyme adsorbed on flexible carbon fiber (FCF) electrodes modified with GO (FCF-GO), where the k(het) between GO and electroactive GOx has been measured at a structurally well-defined interface. Carbon 95-101 hydroxyacid oxidase 1 Homo sapiens 63-66 24676540-4 2014 In this work, we report the experimentally observed DET of the GOx enzyme adsorbed on flexible carbon fiber (FCF) electrodes modified with GO (FCF-GO), where the k(het) between GO and electroactive GOx has been measured at a structurally well-defined interface. Carbon 95-101 hydroxyacid oxidase 1 Homo sapiens 198-201 24961450-1 2014 We describe an ultrasensitive electrochemical nucleic acid assay amplified by carbon nanotubes (CNTs)-based labels for the detection of human acute lymphocytic leukemia (ALL)-related p185 BCR-ABL fusion transcript. Carbon 78-84 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 188-195 29895827-8 2018 Thus, we propose that endothelial cells undergo MTHFD2-mediated reprogramming toward serine-glycine and mitochondrial one-carbon metabolism to compensate for the loss of ATP in response to oxPAPC during atherosclerosis. Carbon 122-128 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 48-54 20570913-0 2010 Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. Carbon 37-43 thymidylate synthetase Homo sapiens 21-25 25012419-1 2014 BACKGROUND: An important biological factor suggested in the pathophysiology of (recurrent) Major Depressive Disorder (MDD) concerns a polymorphism in a gene encoding for the MTHFR-enzyme of the one-carbon (1-C)-metabolism. Carbon 198-204 methylenetetrahydrofolate reductase Homo sapiens 174-179 29866124-5 2018 By expressing an Erg20 mutant to divert carbon flux from FPP to GPP, the geranyl acetate production increased to 2.64 mg/L. Carbon 40-46 bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase Saccharomyces cerevisiae S288C 17-22 20199623-3 2010 Metabolite profiling by gas chromatography-time of flight-mass spectrometry (GC-TOF-MS) and high-performance liquid chromatography (HPLC) revealed that loss of cICDH function produced only small effects on leaf compounds involved in carbon and nitrogen assimilation. Carbon 233-239 cytosolic NADP+-dependent isocitrate dehydrogenase Arabidopsis thaliana 160-165 29654773-3 2018 PSP-2 was the most effective fraction, which was identified as procyanidin B3 mainly and procyanidin dimer [(E)C-luteolin or keampferol] secondarily. Carbon 111-112 regenerating family member 1 beta Homo sapiens 0-5 24810629-5 2014 A homology search indicated that ORF32 encodes a hydratase for the CoA-ester, suggesting that ORF32 encodes a hydratase that adds a water molecule to a double bond at C-6 of the CoA-ester of 9alpha-hydroxy-17-oxo-1,2,3,4,10,19-hexanorandrost-6-en-5-oic acid. Carbon 67-68 Orf32 Comamonas testosteroni 33-38 24810629-5 2014 A homology search indicated that ORF32 encodes a hydratase for the CoA-ester, suggesting that ORF32 encodes a hydratase that adds a water molecule to a double bond at C-6 of the CoA-ester of 9alpha-hydroxy-17-oxo-1,2,3,4,10,19-hexanorandrost-6-en-5-oic acid. Carbon 67-68 Orf32 Comamonas testosteroni 94-99 20394402-4 2010 The direct electron transfer of immobilized Hb was studied by cyclic voltammetry, and the electrocatalytic activity was evaluated at glassy carbon modified with this Mg(2)Al-Hb(cop) biohybrid. Carbon 140-146 caspase recruitment domain family member 16 Homo sapiens 177-180 24384670-0 2014 Isolation and characterization of mutants defective in the localization of LCIB, an essential factor for the carbon-concentrating mechanism in Chlamydomonas reinhardtii. Carbon 109-115 uncharacterized protein Chlamydomonas reinhardtii 75-79 29438858-1 2018 Molybdenum diselenide nanosheet/carbon nanofiber (MoSe2/CNF) heterojunctions have been successfully obtained by a facile two-step synthesis route combining an electrospinning technique and solvothermal method. Carbon 32-38 NPHS1 adhesion molecule, nephrin Homo sapiens 56-59 20357868-0 2010 Tip-enhanced Raman spectroscopy with silver-coated optical fiber probe in reflection mode for investigating multiwall carbon nanotubes. Carbon 118-124 TOR signaling pathway regulator Homo sapiens 0-3 29693092-3 2018 In direct agreement with empirical trends, alkene insertion into Ni-C bonds on COM1 is exclusively favoured over the competing alkyne insertion. Carbon 68-69 nuclear protein 1, transcriptional regulator Homo sapiens 79-83 29494148-2 2018 Molecular modeling showed that the compounds with 10, 12, and 14 carbons chains are associated with higher stabilization of the MD-2/TLR4 antagonist conformation than in the case of the C16 variant. Carbon 65-72 lymphocyte antigen 96 Homo sapiens 128-132 24384670-2 2014 This mechanism is called the carbon-concentrating mechanism (CCM), and soluble protein LCIB is essential for the CCM. Carbon 29-35 uncharacterized protein Chlamydomonas reinhardtii 87-91 24992071-6 2014 Herein, we report on the development of a new class of cationic lipid-Dex conjugates in which the C-8 carbon chain analogue (DX8) exhibited glucocorticoid receptor (GR)-mediated, caspase-3-assisted, cancer cell-selective anti-proliferative activity. Carbon 102-108 caspase 3 Mus musculus 179-188 20684249-3 2010 The cross-coupling of ATP and calix[4]aren C-99 on their orientation in ligand-binding center of subfragment-1 myosin of myometrium has been studied. Carbon 43-44 myosin heavy chain 14 Homo sapiens 111-117 25010666-3 2014 Following calcination under vacuum, a stable ohmic contact was obtained between suspended TiO2-carbon NFs (TiO2/C NF) and the carbon electrodes. Carbon 95-101 NPHS1 adhesion molecule, nephrin Homo sapiens 107-116 25089242-3 2014 Compounds 1 and 2, two new decaoxygenated limonoids with a C-19/29 lactol bridge and heptaoxygenated substituents at C-1, C-2, C-3, C-7, C-11, C-17, and C-30, represent the second example of limonoids in the Euphorbiaceae family. Carbon 0-1 aldo-keto reductase family 1 member C4 Homo sapiens 137-141 29616348-9 2018 This nanohybrid was used for modifying a glassy carbon electrode to develop a sensor electrode for detecting L-cysteine that has fast response (less than 2 s), low detection limit (0.15 muM), and good sensitivity (0.092 muA muM-1 cm-2). Carbon 48-54 PWWP domain containing 3A, DNA repair factor Homo sapiens 224-229 29616360-1 2018 This study introduces a novel titanium dioxide carbon nanofiber (TiO2-CNF) support for anodic catalyst in direct methanol fuel cell. Carbon 47-53 NPHS1 adhesion molecule, nephrin Homo sapiens 70-73 29616360-5 2018 Experimental results show that the TiO2-CNF support gave the highest current density at 345.64 mA mgcatalyst-1, which is equivalent to 5.54-fold that of carbon support while the power density is almost double that of the commercial electrocatalyst. Carbon 153-159 NPHS1 adhesion molecule, nephrin Homo sapiens 40-43 20082776-0 2010 Application of a new potentiometric method for determination of phosphate based on a surfactant-modified zeolite carbon-paste electrode (SMZ-CPE). Carbon 113-119 carboxypeptidase E Homo sapiens 141-144 29590160-2 2018 Biosynthesis of LC-PUFAs from dietary 18 carbon PUFAs in tissues such as the liver is highly associated with genetic variation within the fatty acid desaturase (FADS) gene cluster, containing FADS1 and FADS2 that encode the rate-limiting desaturation enzymes in the LC-PUFA biosynthesis pathway. Carbon 41-47 stearoyl-CoA desaturase Homo sapiens 138-159 29590160-2 2018 Biosynthesis of LC-PUFAs from dietary 18 carbon PUFAs in tissues such as the liver is highly associated with genetic variation within the fatty acid desaturase (FADS) gene cluster, containing FADS1 and FADS2 that encode the rate-limiting desaturation enzymes in the LC-PUFA biosynthesis pathway. Carbon 41-47 stearoyl-CoA desaturase Homo sapiens 161-165 29590160-2 2018 Biosynthesis of LC-PUFAs from dietary 18 carbon PUFAs in tissues such as the liver is highly associated with genetic variation within the fatty acid desaturase (FADS) gene cluster, containing FADS1 and FADS2 that encode the rate-limiting desaturation enzymes in the LC-PUFA biosynthesis pathway. Carbon 41-47 pumilio RNA binding family member 3 Homo sapiens 19-23 24914611-4 2014 Microscopically, a novel carbon nanofiber-graphene nanosheet-carbon nanofiber (CNF-GN-CNF) heterojunction, which plays the dominant role as the interfacial modifier, has been observed in the as-fabricated networks. Carbon 25-31 NPHS1 adhesion molecule, nephrin Homo sapiens 79-89 24914611-4 2014 Microscopically, a novel carbon nanofiber-graphene nanosheet-carbon nanofiber (CNF-GN-CNF) heterojunction, which plays the dominant role as the interfacial modifier, has been observed in the as-fabricated networks. Carbon 61-67 NPHS1 adhesion molecule, nephrin Homo sapiens 79-89 24914611-5 2014 With the presence of CNF-GN-CNF heterojunctions, the all-carbon networks exhibit much increased electrical properties, resulting in the great enhancement of EMI shielding performance. Carbon 57-63 NPHS1 adhesion molecule, nephrin Homo sapiens 21-31 20080721-2 2010 Empirical estimates of [CO(2)](atm) during Paleozoic and Mesozoic greenhouse climates are based primarily on the carbon isotope composition of calcium carbonate in fossil soils. Carbon 113-119 ATM serine/threonine kinase Homo sapiens 31-34 24747731-2 2014 10-Formyltetrahydrofolate dehydrogenase (FDH) is the most abundant folate enzyme in folate-mediated one-carbon metabolism. Carbon 104-110 aldehyde dehydrogenase 1 family, member L1 Danio rerio 0-39 24747731-2 2014 10-Formyltetrahydrofolate dehydrogenase (FDH) is the most abundant folate enzyme in folate-mediated one-carbon metabolism. Carbon 104-110 aldehyde dehydrogenase 1 family, member L1 Danio rerio 41-44 20356215-0 2010 Free-standing carbon nanotube films as optical accumulators for multiplex SERRS attomolar detection. Carbon 14-20 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 74-79 24814332-0 2014 Carbon and nitrogen isotope ratios of factory-produced RDX and HMX. Carbon 0-6 radixin Homo sapiens 55-58 29469565-5 2018 Herein, we apply reduced graphene oxide (rGO)-incorporated SnSb@carbon nanofiber (SnSb@rGO@CNF) composite anodes in SIBs that can sustain their structural stability during prolonged charge-discharge cycles. Carbon 64-70 NPHS1 adhesion molecule, nephrin Homo sapiens 91-94 20807643-6 2010 Chondroitin-4-sulfotransferase-1 (C4ST-1)/carbohydrate sulfotransferase 11 (CHST11) is one of the enzymes involved in the sulfation of chondroitin by catalyzing the transfer of sulfate groups from a sulfate donor to the carbon-4 position of the N-acetylgalactosamine sugar of the repeating disaccharide units. Carbon 220-226 carbohydrate sulfotransferase 11 Homo sapiens 0-32 29458562-3 2018 The Deltamtf2 mutant with the intron-containing mitochondrial DNA (mtDNA) exhibited impaired growth on a rich medium containing the non-fermentable carbon source glycerol, suggesting that mtf2 is involved in mitochondrial function. Carbon 148-154 Mtf2p Saccharomyces cerevisiae S288C 9-13 29281767-3 2018 Here, we report niobium pentoxide/carbon/niobium carbide (MXene) hybrid materials (Nb2 O5 /C/Nb2 C) as photocatalysts for hydrogen evolution from water splitting. Carbon 34-40 contactin 5 Homo sapiens 93-96 29281767-5 2018 Nb2 O5 grew homogeneously on Nb2 C after mild oxidation, during which some amorphous carbon was also formed. Carbon 85-91 contactin 5 Homo sapiens 0-3 24682016-0 2014 A carbon nanotubes based fluorescent aptasensor for highly sensitive detection of adenosine deaminase activity and inhibitor screening in natural extracts. Carbon 2-8 adenosine deaminase Homo sapiens 82-101 24682016-1 2014 A carbon nanotubes (CNTs) based fluorescent aptasensor was developed for adenosine deaminase (ADA) activity detection and inhibitor screening by using adenosine (AD) as the substrate. Carbon 2-8 adenosine deaminase Homo sapiens 73-92 24682016-1 2014 A carbon nanotubes (CNTs) based fluorescent aptasensor was developed for adenosine deaminase (ADA) activity detection and inhibitor screening by using adenosine (AD) as the substrate. Carbon 2-8 adenosine deaminase Homo sapiens 94-97 29190472-0 2018 A fluorescent sensor for detecting dopamine and tyrosinase activity by dual-emission carbon dots and gold nanoparticles. Carbon 85-91 tyrosinase Homo sapiens 48-58 20807643-6 2010 Chondroitin-4-sulfotransferase-1 (C4ST-1)/carbohydrate sulfotransferase 11 (CHST11) is one of the enzymes involved in the sulfation of chondroitin by catalyzing the transfer of sulfate groups from a sulfate donor to the carbon-4 position of the N-acetylgalactosamine sugar of the repeating disaccharide units. Carbon 220-226 carbohydrate sulfotransferase 11 Homo sapiens 34-40 29190472-1 2018 In this work, we report a fluorescence strategy for detecting dopamine (DA) and sensing tyrosinase (TYR) activity on the basis of the dual-emission carbon dots (DECDs), which contain two emitters: the blue emitters (BE, maximum emission at 385nm) and yellow emitters (YE, maximum emission at 530nm). Carbon 148-154 tyrosinase Homo sapiens 88-98 20807643-6 2010 Chondroitin-4-sulfotransferase-1 (C4ST-1)/carbohydrate sulfotransferase 11 (CHST11) is one of the enzymes involved in the sulfation of chondroitin by catalyzing the transfer of sulfate groups from a sulfate donor to the carbon-4 position of the N-acetylgalactosamine sugar of the repeating disaccharide units. Carbon 220-226 carbohydrate sulfotransferase 11 Homo sapiens 42-74 29190472-1 2018 In this work, we report a fluorescence strategy for detecting dopamine (DA) and sensing tyrosinase (TYR) activity on the basis of the dual-emission carbon dots (DECDs), which contain two emitters: the blue emitters (BE, maximum emission at 385nm) and yellow emitters (YE, maximum emission at 530nm). Carbon 148-154 tyrosinase Homo sapiens 100-103 24909769-2 2014 Tyrosinase was immobilized by crosslinking on screen-printed carbon electrodes (SPCEs) containing tetrathiafulvalene (TTF) as electron transfer mediator. Carbon 61-67 tyrosinase Homo sapiens 0-10 24909770-1 2014 A nitrogen-doped graphene/carbon nanotubes (NGR-NCNTs) nanocomposite was employed into the study of the electrochemical sensor via electrodeposition for the first time. Carbon 26-32 reticulon 4 receptor Homo sapiens 44-47 24909770-3 2014 Meanwhile, the electrochemical performance of the glassy carbon electrode (GCE) modified with electrodeposited NGR-NCNTs (ENGR-NCNTs/GCE) towards caffeine (CAF) and vanillin (VAN) determination was demonstrated by cyclic voltammetry (CV) and square wave voltammetry (SWV). Carbon 57-63 reticulon 4 receptor Homo sapiens 111-114 20807643-6 2010 Chondroitin-4-sulfotransferase-1 (C4ST-1)/carbohydrate sulfotransferase 11 (CHST11) is one of the enzymes involved in the sulfation of chondroitin by catalyzing the transfer of sulfate groups from a sulfate donor to the carbon-4 position of the N-acetylgalactosamine sugar of the repeating disaccharide units. Carbon 220-226 carbohydrate sulfotransferase 11 Homo sapiens 76-82 19733474-1 2009 Single-walled carbon nanohorn modified glassy carbon electrode (SWCNH-modified GCE) was first employed for the simultaneous determination of uric acid (UA), dopamine (DA), and ascorbic acid (AA). Carbon 14-20 aminomethyltransferase Homo sapiens 79-82 24837693-1 2014 Novel Pd-Ni alloy nanoparticle/carbon nanofiber (Pd-Ni/CNF) composites were successfully prepared by a simple method involving electrospinning of precursor polyacrylonitrile/Pd(acac)2/Ni(acac)2 nanofibers, followed by a thermal process to reduce metals and carbonize polyacrylonitrile. Carbon 31-37 NPHS1 adhesion molecule, nephrin Homo sapiens 55-58 24607314-3 2014 OMP removal from wastewater treatment plant (WWTP) effluents as a point source is a preferred option with removal by adsorption onto powdered activated carbon (PAC) and OMP transformation to presumably harmless compounds by ozonation as the most promising techniques. Carbon 152-158 olfactory marker protein Homo sapiens 0-3 24666432-6 2014 Relative abundance patterns of carbon number are C10 > C11 > C12 ~ C13 for SCCPs and C14 > C15 > C16 C17 for MCCP with similarity to the profiles of samples from China, the biggest CPs producer in the world. Carbon 31-37 chromosome 12 open reading frame 57 Homo sapiens 49-52 24666432-6 2014 Relative abundance patterns of carbon number are C10 > C11 > C12 ~ C13 for SCCPs and C14 > C15 > C16 C17 for MCCP with similarity to the profiles of samples from China, the biggest CPs producer in the world. Carbon 31-37 RNA polymerase III subunit K Homo sapiens 58-61 24666432-6 2014 Relative abundance patterns of carbon number are C10 > C11 > C12 ~ C13 for SCCPs and C14 > C15 > C16 C17 for MCCP with similarity to the profiles of samples from China, the biggest CPs producer in the world. Carbon 31-37 homeobox C13 Homo sapiens 73-76 28986240-2 2018 P. aeruginosa G6PDH is also a key enzyme in the metabolism of various carbon sources, such as glucose, glycerol, fructose, and mannitol. Carbon 70-76 glucose-6-phosphate dehydrogenase Homo sapiens 14-19 29299582-1 2018 The development of facile and efficient synthetic approaches of carbon quantum dots loaded with mesoporous g-C3N4 (mpg-C3N4/CQDs) is of critical urgency. Carbon 64-70 N-methylpurine DNA glycosylase Homo sapiens 115-118 29456803-2 2018 A cocrystal structure of 18 with a NS3/4A protease complex suggests the presence of a H-bond between the polarized C-H of the CHF2 moiety and the backbone carbonyl of Leu135 of the enzyme. Carbon 115-116 KRAS proto-oncogene, GTPase Homo sapiens 35-38 24666432-6 2014 Relative abundance patterns of carbon number are C10 > C11 > C12 ~ C13 for SCCPs and C14 > C15 > C16 C17 for MCCP with similarity to the profiles of samples from China, the biggest CPs producer in the world. Carbon 31-37 placenta associated 8 Homo sapiens 100-103 19733474-1 2009 Single-walled carbon nanohorn modified glassy carbon electrode (SWCNH-modified GCE) was first employed for the simultaneous determination of uric acid (UA), dopamine (DA), and ascorbic acid (AA). Carbon 46-52 aminomethyltransferase Homo sapiens 79-82 19968344-3 2009 Both experimental and theoretical methods reveal two structures with C(s) (anti, anti) and C(1) (anti, gauche) symmetries, although there are disagreements about which is more stable. Carbon 69-70 heterogeneous nuclear ribonucleoprotein C Homo sapiens 91-95 24325982-2 2014 A novel electrochemical glucose biosensor is constructed based on the direct electrochemistry of GOx at TCS-TiO2 modified glassy carbon electrode. Carbon 129-135 hydroxyacid oxidase 1 Homo sapiens 97-100 28957746-4 2018 The carbon-boron bonds in PBA residues were cleaved by oxidative reaction with H2O2 produced by the enzymatic reaction of LOx. Carbon 4-10 lysyl oxidase Homo sapiens 122-125 19583974-5 2009 We show here that KU55933, an ATM inhibitor could distinctly lower the clonogenic survival in normal human skin fibroblast cells exposed to carbon ion radiation and dramatically impair the normal process for DSB repair. Carbon 140-146 ATM serine/threonine kinase Homo sapiens 30-33 29858792-0 2018 Positron Emission Tomography Imaging of Tumor Apoptosis with a Caspase-Sensitive Nano-Aggregation Tracer [18F]C-SNAT. Carbon 63-64 aralkylamine N-acetyltransferase Homo sapiens 112-116 24147872-2 2014 We report four novel C-propeptide mutations in COL1A1 gene from Chinese OI patients. Carbon 21-23 collagen type I alpha 1 chain Homo sapiens 47-53 24567531-5 2014 T cell-specific deletion of acetyl coenzyme A carboxylase 1 (ACC1), an enzyme that catalyzes conversion of acetyl coenzyme A to malonyl coenzyme A, a carbon donor for long-chain FA synthesis, resulted in impaired peripheral persistence and homeostatic proliferation of CD8(+) T cells in naive mice. Carbon 150-156 acetyl-CoA carboxylase alpha Homo sapiens 28-59 24567531-5 2014 T cell-specific deletion of acetyl coenzyme A carboxylase 1 (ACC1), an enzyme that catalyzes conversion of acetyl coenzyme A to malonyl coenzyme A, a carbon donor for long-chain FA synthesis, resulted in impaired peripheral persistence and homeostatic proliferation of CD8(+) T cells in naive mice. Carbon 150-156 acetyl-CoA carboxylase alpha Homo sapiens 61-65 24567531-5 2014 T cell-specific deletion of acetyl coenzyme A carboxylase 1 (ACC1), an enzyme that catalyzes conversion of acetyl coenzyme A to malonyl coenzyme A, a carbon donor for long-chain FA synthesis, resulted in impaired peripheral persistence and homeostatic proliferation of CD8(+) T cells in naive mice. Carbon 150-156 CD8a molecule Homo sapiens 269-272 29302632-1 2017 The recombinant HbI was fused with a poly-Lys tag ((Lys)6-tagged rHbI) for specific-site covalent immobilization on two carbon nanotube transducer surfaces, i.e., powder and vertically aligned carbon nanotubes. Carbon 120-126 FKBP prolyl isomerase 4 Rattus norvegicus 16-19 29302632-1 2017 The recombinant HbI was fused with a poly-Lys tag ((Lys)6-tagged rHbI) for specific-site covalent immobilization on two carbon nanotube transducer surfaces, i.e., powder and vertically aligned carbon nanotubes. Carbon 120-126 FKBP prolyl isomerase 4 Rattus norvegicus 65-69 19583974-8 2009 Interestingly, we also found that pretreatment with chloroquine, an ATM stimulator could protect cells from carbon ion radiation only at lower doses. Carbon 108-114 ATM serine/threonine kinase Homo sapiens 68-71 29302632-1 2017 The recombinant HbI was fused with a poly-Lys tag ((Lys)6-tagged rHbI) for specific-site covalent immobilization on two carbon nanotube transducer surfaces, i.e., powder and vertically aligned carbon nanotubes. Carbon 193-199 FKBP prolyl isomerase 4 Rattus norvegicus 16-19 29302632-1 2017 The recombinant HbI was fused with a poly-Lys tag ((Lys)6-tagged rHbI) for specific-site covalent immobilization on two carbon nanotube transducer surfaces, i.e., powder and vertically aligned carbon nanotubes. Carbon 193-199 FKBP prolyl isomerase 4 Rattus norvegicus 65-69 19778056-6 2009 On the basis of the proposed mechanism, the glyoxal interaction with alanine through a decarboxylative aldol addition reaction can lead to the formation of 1,2-butanedione with the terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine, and the similar interaction of 1,2-butanedione with a second molecule of alanine can lead to the formation of 3,4-hexanedione with both terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine. Carbon 196-202 complement C2 Homo sapiens 226-229 24296030-6 2014 The low-carbon components of diesel oil volatilize more rapidly, with the effects of wind speed more pronounced on C10 to C15 volatilization than on C16 and higher. Carbon 8-14 placenta associated 8 Homo sapiens 122-125 29599911-5 2018 Quantitative real time PCR analysis showed that expression of apoptosis-related BAX and autophagy-related Beclin1 and ATG7 was significantly enhanced by carbon ion beam alone or in combination with CDDP. Carbon 153-159 beclin 1 Homo sapiens 106-113 19778056-6 2009 On the basis of the proposed mechanism, the glyoxal interaction with alanine through a decarboxylative aldol addition reaction can lead to the formation of 1,2-butanedione with the terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine, and the similar interaction of 1,2-butanedione with a second molecule of alanine can lead to the formation of 3,4-hexanedione with both terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine. Carbon 196-202 complement C2 Homo sapiens 439-442 24031437-3 2009 The aim of present study is to isolate bacteria which can degrade BaP as a sole source of carbon and energy. Carbon 90-96 prohibitin 2 Homo sapiens 66-69 29058431-3 2017 Photoextrusion of dinitrogen from these intermediates enables completely stereoselective formation of all C3a-C3a" and C3a-C7" carbon-carbon bonds and all the associated quaternary stereogenic centers. Carbon 127-133 complement C3 Homo sapiens 106-109 24031437-9 2009 To our best of knowledge, this is the first report showing utilization of BaP as a sole source of carbon and energy by bacteria. Carbon 98-104 prohibitin 2 Homo sapiens 74-77 29058431-3 2017 Photoextrusion of dinitrogen from these intermediates enables completely stereoselective formation of all C3a-C3a" and C3a-C7" carbon-carbon bonds and all the associated quaternary stereogenic centers. Carbon 134-140 complement C3 Homo sapiens 106-109 20038037-0 2009 [Detection of single-walled carbon nanotube bundles by tip-enhanced Raman spectroscopy]. Carbon 28-34 TOR signaling pathway regulator Homo sapiens 55-58 28772201-4 2017 The advantages of the carbon nanoscaffolds used as the support matrix and the MADQUAT employed for the entrapment of ADH versus physisorption were demonstrated via cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Carbon 22-28 aldo-keto reductase family 1 member A1 Homo sapiens 117-120 28772201-5 2017 Our experimental results showed a higher electron transfer, electrocatalytic activity, and rate constant for MADQUAT entrapped ADH on the carbon nanoscaffolds. Carbon 138-144 aldo-keto reductase family 1 member A1 Homo sapiens 127-130 28772201-6 2017 The immobilization of ADH using both MADQUAT and carbon nanoscaffolds exhibited strong potential for the development of an efficient bio-anode for ethanol powered biofuel cells. Carbon 49-55 aldo-keto reductase family 1 member A1 Homo sapiens 22-25 20038037-13 2009 Corresponding with the AFM image, the tip-enhanced near-field Raman of a 100 nm diameter single-walled carbon nanotube (SWNT) bundles was obtained. Carbon 103-109 TOR signaling pathway regulator Homo sapiens 38-41 19716525-6 2009 Organic carbon and nitrogen compounds in leachate in the IAR and the CAR showed significant decreases in comparison to those in the CR. Carbon 8-14 protein tyrosine phosphatase receptor type N2 Homo sapiens 57-60 28501380-3 2017 Gene PEPC1 encoding proteins are essential for controlling the carbon flux that enters the TCA cycle and plays a crucial role in carbon partitioning of substrates in competition with lipid synthesis. Carbon 129-135 uncharacterized protein Chlamydomonas reinhardtii 5-10 28501380-3 2017 Gene PEPC1 encoding proteins are essential for controlling the carbon flux that enters the TCA cycle and plays a crucial role in carbon partitioning of substrates in competition with lipid synthesis. Carbon 63-69 uncharacterized protein Chlamydomonas reinhardtii 5-10 19908505-0 2009 Electrocatalyzed O2 response of myoglobin immobilized on multi-walled carbon nanotube forest electrodes. Carbon 70-76 myoglobin Homo sapiens 32-41 19908505-1 2009 Direct electrochemistry and activity of myoglobin (Mb) immobilized on carbon nanotube (CNT) forest electrodes were investigated by probing mainly its electrocatalytical response towards oxygen. Carbon 70-76 myoglobin Homo sapiens 40-49 19908505-1 2009 Direct electrochemistry and activity of myoglobin (Mb) immobilized on carbon nanotube (CNT) forest electrodes were investigated by probing mainly its electrocatalytical response towards oxygen. Carbon 70-76 myoglobin Homo sapiens 51-53 19619564-1 2009 Sarcosine is an endogenous amino acid that is a competitive inhibitor of the type I glycine transporter (GlyT1), an N-methyl-d-aspartate receptor (NMDAR) co-agonist, and an important intermediate in one-carbon metabolism. Carbon 203-209 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 Mus musculus 105-110 19671979-0 2009 Enhancing the electrochemical response of myoglobin with carbon nanotube electrodes. Carbon 57-63 myoglobin Homo sapiens 42-51 19671979-1 2009 In this paper, the electrochemical behavior of different myoglobin-modified carbon electrodes is evaluated. Carbon 76-82 myoglobin Homo sapiens 57-66 19671979-7 2009 These findings encourage the use of myoglobin-modified carbon nanotube electrodes as potential (bio)sensors of H(2)O(2) or O(2) in biology, microbiology and environmental fields. Carbon 55-61 myoglobin Homo sapiens 36-45 19534677-4 2009 The derived QSAR models demonstrated that the COX-2 selectivity over COX-1 is predominantly influenced by the central core -N=C- of the diaryl system. Carbon 46-47 mitochondrially encoded cytochrome c oxidase I Homo sapiens 69-74 27877301-3 2009 Moreover, the electrochemical behavior and electrocatalysis of the carbon paste electrode (Cu-CPE) bulk-modified by the complex have been studied in detail. Carbon 67-73 carboxypeptidase E Homo sapiens 94-97 19635904-2 2009 Polyinosinic-polycytidylic acid (poly I:C), a double-stranded RNA analog recognized by melanoma-differentiation associated gene 5 (MDA5) and TLR3, activates NK cells in vivo. Carbon 40-41 interferon induced with helicase C domain 1 Homo sapiens 87-129 19635904-2 2009 Polyinosinic-polycytidylic acid (poly I:C), a double-stranded RNA analog recognized by melanoma-differentiation associated gene 5 (MDA5) and TLR3, activates NK cells in vivo. Carbon 40-41 interferon induced with helicase C domain 1 Homo sapiens 131-135 19719255-2 2009 In the presence of CsF and THF, the carbon-carbon sigma-bonds of 2-oxopropylphosphonates were selectively cleaved and added to arynes providing the corresponding 2-acylbenzylphosphonates in moderate to good yields. Carbon 36-42 colony stimulating factor 2 Homo sapiens 19-22 19719255-2 2009 In the presence of CsF and THF, the carbon-carbon sigma-bonds of 2-oxopropylphosphonates were selectively cleaved and added to arynes providing the corresponding 2-acylbenzylphosphonates in moderate to good yields. Carbon 43-49 colony stimulating factor 2 Homo sapiens 19-22 19842489-4 2009 Complexes of C(NH3)2, C(PH3)2, C[P(CH3)3]2, CF2, CCl2, and imidazol-2-ylidene with such proton donors as H2O, HCF3, HCN and HCCH have been analyzed by means of high-level quantum chemical methods. Carbon 0-1 C-C motif chemokine ligand 2 Homo sapiens 49-53 19842489-4 2009 Complexes of C(NH3)2, C(PH3)2, C[P(CH3)3]2, CF2, CCl2, and imidazol-2-ylidene with such proton donors as H2O, HCF3, HCN and HCCH have been analyzed by means of high-level quantum chemical methods. Carbon 0-1 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 116-119 19448666-5 2009 We demonstrate that endogenous c-myc increased (13)C labeling of ribose sugars, purines and amino acids, indicating partitioning of glucose carbons into C1/folate and pentose phosphate pathways, and increased tricarboxylic acid cycle turnover at the expense of anaplerotic flux. Carbon 140-147 MYC proto-oncogene, bHLH transcription factor Homo sapiens 31-36 19437455-1 2009 In the acetylenic aldehyde oximes with substituents containing silicon and germanium, the (13)C NMR signal of the C-2 carbon of triple bond is shifted by 3.5 ppm to lower frequency and that of the C-3 carbon is moved by 7 ppm to higher frequency on going from E to Z isomer. Carbon 118-124 complement C2 Homo sapiens 114-117 19437455-1 2009 In the acetylenic aldehyde oximes with substituents containing silicon and germanium, the (13)C NMR signal of the C-2 carbon of triple bond is shifted by 3.5 ppm to lower frequency and that of the C-3 carbon is moved by 7 ppm to higher frequency on going from E to Z isomer. Carbon 201-207 complement C2 Homo sapiens 114-117 19437455-2 2009 A greater low-frequency effect of 5.5 ppm on the C-2 carbon signal and a greater high-frequency effect of 11 ppm on the C-3 carbon signal are observed in the analogous acetylenic ketone oximes. Carbon 53-59 complement C2 Homo sapiens 49-52 19791508-2 2009 By comparing the interactions of each analogue with beta-tubulin, the structure-activity relationships are summarized as follow: C-2 benzoyl and taxane ring systems are the essential groups for microtubule binding, the improvements of bioactivity and bioavailability are dependent on the substituents at positions C-1, C-4, C-7, C-9, C-10, and C-14, whereas the C-13 side chain mainly provides a specific binding. Carbon 129-130 heterogeneous nuclear ribonucleoprotein C Homo sapiens 314-317 24510589-6 2014 Given the importance of liberation of fatty acids from lipid droplets, we propose that the physiological function of SAMS-1, a highly conserved enzyme involved in one-carbon metabolism, is the limitation of fat storage to ensure proper growth and reproduction. Carbon 167-173 putative S-adenosylmethionine synthase 1 Caenorhabditis elegans 117-123 19791508-2 2009 By comparing the interactions of each analogue with beta-tubulin, the structure-activity relationships are summarized as follow: C-2 benzoyl and taxane ring systems are the essential groups for microtubule binding, the improvements of bioactivity and bioavailability are dependent on the substituents at positions C-1, C-4, C-7, C-9, C-10, and C-14, whereas the C-13 side chain mainly provides a specific binding. Carbon 129-130 complement C4A (Rodgers blood group) Homo sapiens 319-322 19548727-7 2009 The interaction energy for water clusters extrapolated to an infinite number of carbon atoms amounts to -13.0 and -15.8 kJ/mol with SCS-MP2 and DFT-D, respectively. Carbon 80-86 tryptase pseudogene 1 Homo sapiens 136-139 24502429-0 2014 IL-33 modulates chronic airway resistance changes induced by multi-walled carbon nanotubes. Carbon 74-80 interleukin 33 Mus musculus 0-5 19440050-8 2009 The two yeast PAS kinase homologs, Psk1 and Psk2, are activated by two stimuli, cell integrity stress and nonfermentative carbon sources. Carbon 122-128 PAS domain containing serine/threonine kinase Mus musculus 14-24 24456472-2 2014 Continued research investigation of the N-alkyl substituent of this series, focused in particular on a previously underutilized interaction in a shallow cleft on the MDM2 surface, led to the discovery of a one-carbon tethered sulfone which gave rise to substantial improvements in biochemical and cellular potency. Carbon 210-216 MDM2 proto-oncogene Homo sapiens 166-170 24533076-1 2014 BACKGROUND: Genome-wide association studies on components of the one-carbon metabolic pathway revealed that human vitamin B12 levels could be significantly influenced by variations in the fucosyltransferase 2 (FUT2), cubilin (CUBN), and transcobalamin-I (TCN1) genes. Carbon 69-75 cubilin Homo sapiens 217-224 24533076-1 2014 BACKGROUND: Genome-wide association studies on components of the one-carbon metabolic pathway revealed that human vitamin B12 levels could be significantly influenced by variations in the fucosyltransferase 2 (FUT2), cubilin (CUBN), and transcobalamin-I (TCN1) genes. Carbon 69-75 cubilin Homo sapiens 226-230 28944671-7 2017 We designed a targeted selective reaction monitoring (SRM) method to follow up one-carbon metabolism adaptation in mouse HCC and in regenerating liver following exposure to CCl4. Carbon 83-89 chemokine (C-C motif) ligand 4 Mus musculus 173-177 24422429-4 2014 After C-Br substitution by a series of tertiary amines, ionic liquid Cx-50 copolyoxetanes were obtained, where 50 is the mole percent of quaternary repeat units and "x" is quaternary alkyl chain length (2, 6, 8, 10, 12, 14, or 16 carbons). Carbon 230-237 gap junction protein alpha 8 Homo sapiens 69-74 19440050-8 2009 The two yeast PAS kinase homologs, Psk1 and Psk2, are activated by two stimuli, cell integrity stress and nonfermentative carbon sources. Carbon 122-128 serine/threonine protein kinase PSK2 Saccharomyces cerevisiae S288C 44-48 28525951-6 2017 The distribution of spin up and spin down states at the bridge carbon atom plays a dominant role in the perfect spin filtering. Carbon 63-69 spindlin 1 Homo sapiens 20-24 19362180-0 2009 An electrochemical biosensor for detection of PML/RARA fusion gene using capture probe covalently immobilized onto poly-calcon carboxylic acid modified glassy carbon electrode. Carbon 159-165 PML nuclear body scaffold Homo sapiens 46-49 28525951-6 2017 The distribution of spin up and spin down states at the bridge carbon atom plays a dominant role in the perfect spin filtering. Carbon 63-69 spindlin 1 Homo sapiens 32-36 28525951-6 2017 The distribution of spin up and spin down states at the bridge carbon atom plays a dominant role in the perfect spin filtering. Carbon 63-69 spindlin 1 Homo sapiens 32-36 19362180-0 2009 An electrochemical biosensor for detection of PML/RARA fusion gene using capture probe covalently immobilized onto poly-calcon carboxylic acid modified glassy carbon electrode. Carbon 159-165 retinoic acid receptor alpha Homo sapiens 50-54 24394775-0 2014 The carbon/nitrogen regulator ARABIDOPSIS TOXICOS EN LEVADURA31 controls papilla formation in response to powdery mildew fungi penetration by interacting with SYNTAXIN OF PLANTS121 in Arabidopsis. Carbon 4-10 syntaxin Arabidopsis thaliana 159-167 19394899-0 2009 Electrochemistry of myoglobin in Nafion and multi-walled carbon nanotubes modified carbon ionic liquid electrode. Carbon 57-63 myoglobin Homo sapiens 20-29 23870498-7 2014 BDE 209 and Sigma19PBDE had statistically significant correlations with total organic carbon, the lower brominated congeners had a poor correlation with total organic carbon. Carbon 86-92 homeobox D13 Homo sapiens 0-3 28961890-13 2017 Conclusions: Lack of rRNA recycling in rns2-2 cells triggers a change in carbon flux, which is redirected through the PPP to produce ribose-5-phosphate for de novo nucleoside synthesis. Carbon 73-79 ribonuclease 2 Arabidopsis thaliana 39-43 19394899-0 2009 Electrochemistry of myoglobin in Nafion and multi-walled carbon nanotubes modified carbon ionic liquid electrode. Carbon 83-89 myoglobin Homo sapiens 20-29 29087179-6 2017 Even at 50 C (10 A g-1), the electrode afforded a discharge capacity of 68 mAh g-1 and delivered approximately 104 mAh g-1 (1 C) at -10 C with the help of Mn doping and carbon coating. Carbon 170-176 proline rich protein BstNI subfamily 3 Homo sapiens 79-127 19394899-1 2009 The direct electrochemistry of myoglobin (Mb) entrapped in the Nafion film on a multi-walled carbon nanotubes (MWCNTs) modified carbon ionic liquid electrode (CILE) had been investigated in this paper. Carbon 93-99 myoglobin Homo sapiens 31-40 24516460-0 2013 Use of Plackett-Burman design for rapid screening of nitrogen and carbon sources for the production of lipase in solid state fermentation by Yarrowia lipolytica from mustard oil cake (Brassica napus). Carbon 66-72 lipase-like Brassica napus 103-109 19394899-1 2009 The direct electrochemistry of myoglobin (Mb) entrapped in the Nafion film on a multi-walled carbon nanotubes (MWCNTs) modified carbon ionic liquid electrode (CILE) had been investigated in this paper. Carbon 93-99 myoglobin Homo sapiens 42-44 19394899-1 2009 The direct electrochemistry of myoglobin (Mb) entrapped in the Nafion film on a multi-walled carbon nanotubes (MWCNTs) modified carbon ionic liquid electrode (CILE) had been investigated in this paper. Carbon 128-134 myoglobin Homo sapiens 31-40 28341405-0 2017 Synthesis of novel C-9 carbon substituted derivatives of artemisinin. Carbon 23-29 complement C9 Homo sapiens 19-22 24908294-6 2014 For this purpose, a 3D biosensor was composed of multi-walled carbon nanotubes with carboxylic acid functionalities (multi-walled carbon nanotubes-COOH) to increase the surface area for the range of human IL-10 detection. Carbon 62-68 interleukin 10 Homo sapiens 205-210 24908294-6 2014 For this purpose, a 3D biosensor was composed of multi-walled carbon nanotubes with carboxylic acid functionalities (multi-walled carbon nanotubes-COOH) to increase the surface area for the range of human IL-10 detection. Carbon 130-136 interleukin 10 Homo sapiens 205-210 19394899-1 2009 The direct electrochemistry of myoglobin (Mb) entrapped in the Nafion film on a multi-walled carbon nanotubes (MWCNTs) modified carbon ionic liquid electrode (CILE) had been investigated in this paper. Carbon 128-134 myoglobin Homo sapiens 42-44 18996626-6 2009 Further SAR studies of GA derivatives indicated that modification of carbon-carbon double bond at C-32/33 or C-37/38 and of the methyl groups at C-39/C-35 can improve antitumor activity. Carbon 69-75 chemokine like factor Homo sapiens 98-102 24451681-4 2014 The highest scoring pathway is mitochondrial one-carbon metabolism and is centred on MTHFD2. Carbon 49-55 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 85-91 29209606-1 2017 Carbon domains have been obtained at the surface of a MoS2/TiO2 (Evonik, P25) system via oligomerization and cyclotrimerization reactions involved in the interaction of the photoactive material with acetylene. Carbon 0-6 tubulin polymerization promoting protein Homo sapiens 73-76 19486528-9 2009 Importantly, TLR3 KO mice were protected from poly(I:C)-induced changes in lung function at baseline, which correlated with milder inflammation in the lung, and significantly reduced epithelial cell hypertrophy. Carbon 53-54 toll-like receptor 3 Mus musculus 13-17 28914479-2 2017 Here, a freestanding lotus root-like carbon fiber network decorated with CoS2 nanoparticles (denoted as CoS2 @LRC) has been designed and prepared as the SeS2 host for enhancing the lithium storage performance. Carbon 37-43 secernin 2 Homo sapiens 153-157 24749724-6 2014 Structure-activity relationships were investigated and the preliminary conclusions are summarised as follows: the glycosyl at C-3 and C-26 can increase the activity, the double bond between C-20 and C-22 might be important for the anti-depressive activity, the R-configuration at C-22 and S-configuration at C-20 are necessary for its anti-depressive activity. Carbon 126-127 Sp7 transcription factor 7 Mus musculus 199-203 19358583-1 2009 We report an approach that allows the efficient synthesis of the designed sphingoid base analogues in which the conformational restriction is introduced by incorporation of a cyclic moiety between the 2-amino group and the C-4 carbon atom of the sphingoid base. Carbon 227-233 complement C4A (Rodgers blood group) Homo sapiens 223-226 24164324-1 2013 Methionine synthase (MetH) catalyzes the transfer of a methyl group from methyltetrahydrofolate (CH3-H4Folate) to the cob(I)alamin intermediate to form an organometallic Co-C bond, a reaction similar to that of CH3-H4Folate:corrinoid/iron-sulfur protein (CFeSP) methyltransferase (MeTr). Carbon 97-98 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 0-19 24164324-1 2013 Methionine synthase (MetH) catalyzes the transfer of a methyl group from methyltetrahydrofolate (CH3-H4Folate) to the cob(I)alamin intermediate to form an organometallic Co-C bond, a reaction similar to that of CH3-H4Folate:corrinoid/iron-sulfur protein (CFeSP) methyltransferase (MeTr). Carbon 97-98 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 21-25 28914479-3 2017 The integrated electrode is constructed by three-dimensional interconnected multichannel carbon fibers, which can not only accommodate high content of SeS2 (70 wt %), but also promise excellent electron and ion transport for achieving high capacity utilization of 1015 mAh g-1 at 0.2 A g-1 . Carbon 89-95 secernin 2 Homo sapiens 151-155 28645764-1 2017 In this study, we developed a novel composite material containing biological macromolecules like heparin and chitosan coated on reduced graphene oxide (rGO) for the modification of glassy carbon electrode (hep/CS-rGO/GC). Carbon 188-194 DNL-type zinc finger Homo sapiens 97-100 19534119-0 2009 LFERs for soil organic carbon-water distribution coefficients (Koc) at environmentally relevant sorbate concentrations. Carbon 23-29 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 63-66 23856812-7 2013 n-Alkanol in all sediment exhibits even-to-odd carbon predominance ranging from nC16 to nC28 and maximising at nC22. Carbon 47-53 C-C motif chemokine ligand 7 Homo sapiens 88-92 19493007-1 2009 The glycolytic enzyme triosephosphate isomerase (tpi) (EC 5.3.1.1) plays a key role in central carbon metabolism yet few studies have characterized isogenic bacterial mutants lacking this enzyme and none have examined its role in the in vivo fitness of a bacterial pathogen. Carbon 95-101 triosephosphate isomerase 1 Mus musculus 49-52 24180258-1 2013 We report on a novel sensing platform for H2O2 and glucose based on immobilization of palladium-helical carbon nanofiber (Pd-HCNF) hybrid nanostructures and glucose oxidase (GOx) with Nafion on a glassy carbon electrode (GCE). Carbon 203-209 hydroxyacid oxidase 1 Homo sapiens 157-172 24180258-1 2013 We report on a novel sensing platform for H2O2 and glucose based on immobilization of palladium-helical carbon nanofiber (Pd-HCNF) hybrid nanostructures and glucose oxidase (GOx) with Nafion on a glassy carbon electrode (GCE). Carbon 203-209 hydroxyacid oxidase 1 Homo sapiens 174-177 24180258-8 2013 Furthermore, a sensing platform for glucose was prepared by immobilizing the Pd-HCNFs and glucose oxidase (GOx) with Nafion on a glassy carbon electrode. Carbon 136-142 hydroxyacid oxidase 1 Homo sapiens 90-105 24180258-8 2013 Furthermore, a sensing platform for glucose was prepared by immobilizing the Pd-HCNFs and glucose oxidase (GOx) with Nafion on a glassy carbon electrode. Carbon 136-142 hydroxyacid oxidase 1 Homo sapiens 107-110 28972750-0 2017 Low-Valent, High-Spin Chromium-Catalyzed Cleavage of Aromatic Carbon-Nitrogen Bonds at Room Temperature: A Combined Experimental and Theoretical Study. Carbon 62-68 spindlin 1 Homo sapiens 17-21 28499167-1 2017 The electrochemical responses of human centrin 3 (HsCen3) binding with hemin were studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) using glassy carbon electrodes (GCEs). Carbon 171-177 centrin 3 Homo sapiens 39-48 28501601-2 2017 The results showed that the inter-molecular interactions or hydrogen bond formation by increasing length of carbon chain or introducing benzene ring to the 4-functionalized ester group promoted or stabilized formation of complexes between modifier and tyrosinase, and enhanced the inhibitory activity of modifiers. Carbon 108-114 tyrosinase Homo sapiens 252-262 24148477-0 2013 A high-performance glucose biosensor using covalently immobilised glucose oxidase on a poly(2,6-diaminopyridine)/carbon nanotube electrode. Carbon 113-119 hydroxyacid oxidase 1 Homo sapiens 66-81 24148477-1 2013 A highly-sensitive glucose biosensor amenable to ultra-miniaturisation was fabricated by immobilisation of glucose oxidase (GOx), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWNT/GCE). Carbon 176-182 hydroxyacid oxidase 1 Homo sapiens 107-122 19251849-9 2009 Mutants lacking mqo function grow more slowly in culture than wild-type bacteria when dicarboxylates are the only available carbon source. Carbon 124-130 malate dehydrogenase (quinone) Pseudomonas syringae pv. tomato str. DC3000 16-19 24148477-1 2013 A highly-sensitive glucose biosensor amenable to ultra-miniaturisation was fabricated by immobilisation of glucose oxidase (GOx), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWNT/GCE). Carbon 176-182 hydroxyacid oxidase 1 Homo sapiens 124-127 24148477-1 2013 A highly-sensitive glucose biosensor amenable to ultra-miniaturisation was fabricated by immobilisation of glucose oxidase (GOx), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWNT/GCE). Carbon 199-205 hydroxyacid oxidase 1 Homo sapiens 107-122 24148477-1 2013 A highly-sensitive glucose biosensor amenable to ultra-miniaturisation was fabricated by immobilisation of glucose oxidase (GOx), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWNT/GCE). Carbon 199-205 hydroxyacid oxidase 1 Homo sapiens 124-127 24112657-6 2013 Treatment with an ozone dose of 50mgL(-1) improved the 84d biodegradability of remaining dissolved organic carbon during subsequent aerobic incubation (11-13mgL(-1) removed from aged process-affected waters versus 5mgL(-1) when not pretreated with ozone). Carbon 107-113 LLGL scribble cell polarity complex component 1 Homo sapiens 34-40 24112657-6 2013 Treatment with an ozone dose of 50mgL(-1) improved the 84d biodegradability of remaining dissolved organic carbon during subsequent aerobic incubation (11-13mgL(-1) removed from aged process-affected waters versus 5mgL(-1) when not pretreated with ozone). Carbon 107-113 LLGL scribble cell polarity complex component 1 Homo sapiens 157-163 24127525-6 2013 The mutation Y318S in hSlo1, which replaces Y with S as found in dSlo1, greatly diminishes the channel"s response to DHA with a 22-carbon chain whether beta1 or beta4 is absent or present. Carbon 131-137 potassium calcium-activated channel subfamily M alpha 1 Homo sapiens 22-27 28916983-10 2017 Together, these results suggest that the optimum value of carbon ion implantation in silicone rubber to enhance biocompatibility is 1 x 1016 ions/cm2, and ion implantation regulates conformational changes of adsorbed ECM proteins, such as VN, and mediates the expression of intracellular signals that enhance the biocompatibility of silicone rubber. Carbon 58-64 vitronectin Homo sapiens 239-241 28594639-0 2017 Spin-valley dynamics of electrically driven ambipolar carbon-nanotube quantum dots. Carbon 54-60 spindlin 1 Homo sapiens 0-4 19366229-0 2009 Nucleation and growth of thin films of the organic conductor TTF-iodide over glassy carbon. Carbon 84-90 ras homolog family member H Homo sapiens 61-64 28598615-0 2017 Induction of Slug by Chronic Exposure to Single-Walled Carbon Nanotubes Promotes Tumor Formation and Metastasis. Carbon 55-61 snail family transcriptional repressor 2 Homo sapiens 13-17 24087851-3 2013 Moreover, the dimerization of tertiary bromide 6 efficiently establishes sterically hindered vicinal quaternary carbons (C3a and C3a"), which is a key linkage of intriguing bispyrrolo[2,3-b]indoline alkaloids, thereby enabling us to complete the total syntheses of racemic chimonanthine (9) and folicanthine (10). Carbon 112-119 complement C3 Homo sapiens 121-124 24087851-3 2013 Moreover, the dimerization of tertiary bromide 6 efficiently establishes sterically hindered vicinal quaternary carbons (C3a and C3a"), which is a key linkage of intriguing bispyrrolo[2,3-b]indoline alkaloids, thereby enabling us to complete the total syntheses of racemic chimonanthine (9) and folicanthine (10). Carbon 112-119 complement C3 Homo sapiens 129-132 19366229-2 2009 On the basis of the electrochemical and spectroelectrochemical behavior of thin films of TTF over a glassy carbon electrode in iodide media, a new, more complete mechanism for the electrode processes involved is proposed. Carbon 107-113 ras homolog family member H Homo sapiens 89-92 24056988-5 2013 The triplet energy surface has a minimum at a bisected geometry (plus its enantiomer); rotation of the H-C-CN segments of the triplet yields a syn-periplanar and an anti-periplanar point 9.3 kcal mol(-1) and 8.2 kcal mol(-1) above the minimum, respectively. Carbon 105-106 synemin Homo sapiens 143-146 28716119-0 2017 STAT1-dependent and -independent pulmonary allergic and fibrogenic responses in mice after exposure to tangled versus rod-like multi-walled carbon nanotubes. Carbon 140-146 signal transducer and activator of transcription 1 Mus musculus 0-5 19275130-3 2009 In order to study the pathway involved in C(1)-N(2) bond cleavage, the electronic character of the carbon atom at C-1 was altered by substitution of electron-rich and electron-poor phenyl rings at this position. Carbon 99-105 heterogeneous nuclear ribonucleoprotein C Homo sapiens 42-46 27614682-0 2017 A rapid and highly sensitive immunoassay format for human lipocalin-2 using multiwalled carbon nanotubes. Carbon 88-94 lipocalin 2 Homo sapiens 58-69 27614682-1 2017 A sensitive and rapid sandwich immunoassay (IA) was developed for human lipocalin-2 (LCN2) by functionalizing a KOH-treated polystyrene microtiter plate with multiwalled carbon nanotubes (MWCNTs) dispersed in 3-aminoproyltriethoxysilane (APTES). Carbon 170-176 lipocalin 2 Homo sapiens 72-83 24301750-6 2013 Glycerol dehydrogenase and phosphate acetyltransferase, which are involved in carbon metabolism and have been associated with virulence in some bacteria, were downregulated. Carbon 78-84 acetyltransferase Escherichia coli 37-54 19275130-3 2009 In order to study the pathway involved in C(1)-N(2) bond cleavage, the electronic character of the carbon atom at C-1 was altered by substitution of electron-rich and electron-poor phenyl rings at this position. Carbon 99-105 heterogeneous nuclear ribonucleoprotein C Homo sapiens 114-117 32261099-3 2013 As a proof of concept, in order to detect glucose concentration, we fabricate an electroconductive polyacrylamide glucose oxidase (GOx) loaded hydrogel (HY) modified with a small amount of single-walled carbon nanotubes (SWNTs) (up to 0.85 wt%). Carbon 203-209 hydroxyacid oxidase 1 Homo sapiens 114-129 32261099-3 2013 As a proof of concept, in order to detect glucose concentration, we fabricate an electroconductive polyacrylamide glucose oxidase (GOx) loaded hydrogel (HY) modified with a small amount of single-walled carbon nanotubes (SWNTs) (up to 0.85 wt%). Carbon 203-209 hydroxyacid oxidase 1 Homo sapiens 131-134 27614682-1 2017 A sensitive and rapid sandwich immunoassay (IA) was developed for human lipocalin-2 (LCN2) by functionalizing a KOH-treated polystyrene microtiter plate with multiwalled carbon nanotubes (MWCNTs) dispersed in 3-aminoproyltriethoxysilane (APTES). Carbon 170-176 lipocalin 2 Homo sapiens 85-89 19472650-3 2009 A software tool combining a fast symmetric demons algorithm and the use of masks was developed in C++ based on ITK libraries to register CT images acquired at planning and before treatment fractions. Carbon 98-100 IL2 inducible T cell kinase Homo sapiens 111-114 27669895-0 2017 Isolation, purification and analysis of dissolved organic carbon from Gohagoda uncontrolled open dumpsite leachate, Sri Lanka. Carbon 58-64 sorcin Homo sapiens 116-119 23900692-6 2013 DNA methylation is an epigenetic mechanism for gene regulation engaged by DNA methyltransferase (Dnmt)-catalyzed methyl group transfer to carbon-5 in cytosine residues in gene regulatory promoter and nonpromoter regions. Carbon 138-144 DNA methyltransferase 1 Homo sapiens 74-95 19115824-4 2009 DFT was found to give significantly longer halide ion/carbon atom bond lengths for the ion-dipole complexes and central barrier transition state than MP2. Carbon 54-60 tryptase pseudogene 1 Homo sapiens 150-153 23900692-6 2013 DNA methylation is an epigenetic mechanism for gene regulation engaged by DNA methyltransferase (Dnmt)-catalyzed methyl group transfer to carbon-5 in cytosine residues in gene regulatory promoter and nonpromoter regions. Carbon 138-144 DNA methyltransferase 1 Homo sapiens 97-101 23824605-0 2013 TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells. Carbon 43-49 sarcosine dehydrogenase Homo sapiens 11-16 23824605-4 2013 Here, we further characterize the functional interaction between TMEFF2 and SARDH and their link with one-carbon (1-C) metabolism and invasion. Carbon 106-112 sarcosine dehydrogenase Homo sapiens 76-81 23824605-7 2013 Real-time PCR and Western blot of subcellular fractions were used to study the effect of SARDH KD or TMEFF2 KD on expression of enzymes involved in one-carbon (1-C) metabolism and on TMEFF2 expression and localization. Carbon 152-158 sarcosine dehydrogenase Homo sapiens 89-94 24019487-10 2013 The consistent patterns reflected in these relationships provide a strong basis for including estimates of regional and seasonal carbohydrate and dEPS carbon budgets in coupled physical-biogeochemical models, across different types of sea ice from both polar regions. Carbon 151-157 14-3-3epsilon Drosophila melanogaster 146-150 28654017-4 2017 Since neurological diseases are characterized by increased free radical generation and the highest concentrations of Vit C in the body are found in the brain and neuroendocrine tissues, it is suggested that Vit C may change the course of neurological diseases and display potential therapeutic roles. Carbon 121-122 vitrin Mus musculus 117-120 28654017-4 2017 Since neurological diseases are characterized by increased free radical generation and the highest concentrations of Vit C in the body are found in the brain and neuroendocrine tissues, it is suggested that Vit C may change the course of neurological diseases and display potential therapeutic roles. Carbon 121-122 vitrin Mus musculus 207-210 28481500-0 2017 Novel Single-Cell Analysis Platform Based on a Solid-State Zinc-Coadsorbed Carbon Quantum Dots Electrochemiluminescence Probe for the Evaluation of CD44 Expression on Breast Cancer Cells. Carbon 75-81 CD44 molecule (Indian blood group) Homo sapiens 148-152 19708115-3 2009 This difference in the mechanism of electron transfer initiated bond cleavage is attributed to the solvent specific effects, namely, stabilization of CCl4*- intermediate radical anion in RTIL, which in turn decreases the electron transfer rate and thus the carbon-halogen bond cleavage rates. Carbon 257-263 C-C motif chemokine ligand 4 Homo sapiens 150-154 28452486-2 2017 Herein, we demonstrate a facile synthetic route to fabricate cobalt and nitrogen codoped carbon nanopolyhedra with hierarchically porous structure (Co,N-HCNP) by one-step carbonization of core-shell structured ZIF-8@ZIF-67 crystals. Carbon 89-95 XPA binding protein 2 Homo sapiens 153-157 23845050-3 2013 This hydrophilic redox nanomaterial could be mixed with glucose oxidase (GOx) for drop-coating on a screen-printed carbon electrode (SPCE) for glucose sensing application. Carbon 115-121 hydroxyacid oxidase 1 Homo sapiens 56-71 23845050-3 2013 This hydrophilic redox nanomaterial could be mixed with glucose oxidase (GOx) for drop-coating on a screen-printed carbon electrode (SPCE) for glucose sensing application. Carbon 115-121 hydroxyacid oxidase 1 Homo sapiens 73-76 19382701-2 2009 The mutant strains possessed defects in genes MTH1 and MTH2 which resulted in the inability to assimilate methanol as a sole carbon source and the increased activity of alcohol oxidase (AO). Carbon 125-131 Mth1p Saccharomyces cerevisiae S288C 46-50 23817588-1 2013 An electrochemiluminescence sensor for adrenaline based on a tyrosinase/SiC/chitosan film modified glassy carbon electrode was fabricated, and the proposed sensor showed high sensitivity and excellent biocompatibility. Carbon 106-112 tyrosinase Homo sapiens 61-71 23878229-4 2013 Here, we show that the two paralogous GATA transcription factors GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 (CGA1) are direct and critical transcription targets downstream from ARF2 in the control of greening, flowering time, and senescence. Carbon 90-96 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 38-42 28509848-1 2017 In this research work, electrochemical biosensor was fabricated based on immobilization of tyrosinase onto graphene-decorated gold nanoparticle/chitosan (Gr-Au-Chit/Tyr) nanocomposite-modified screen-printed carbon electrode (SPCE) for the detection of phenolic compounds. Carbon 208-214 tyrosinase Homo sapiens 91-101 28411188-6 2017 Simultaneously, RKIP enhances the Poly(I:C)-induced interaction between TGF-beta-activated kinase 1 and MAPK kinase 3 (MKK3), thus promoting MKK3/6 and p38 activation. Carbon 41-42 phosphatidylethanolamine binding protein 1 Mus musculus 16-20 23878229-4 2013 Here, we show that the two paralogous GATA transcription factors GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 (CGA1) are direct and critical transcription targets downstream from ARF2 in the control of greening, flowering time, and senescence. Carbon 90-96 cytokinin-responsive gata factor 1 Arabidopsis thaliana 142-175 19166340-1 2009 We report on the observation of the natural isotopic spread of carbon from single-molecule surface-enhanced Raman spectroscopy (SM-SERS). Carbon 63-69 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 131-135 23878229-4 2013 Here, we show that the two paralogous GATA transcription factors GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 (CGA1) are direct and critical transcription targets downstream from ARF2 in the control of greening, flowering time, and senescence. Carbon 90-96 cytokinin-responsive gata factor 1 Arabidopsis thaliana 177-181 23878229-4 2013 Here, we show that the two paralogous GATA transcription factors GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 (CGA1) are direct and critical transcription targets downstream from ARF2 in the control of greening, flowering time, and senescence. Carbon 90-96 auxin response factor 2 Arabidopsis thaliana 245-249 28541935-5 2017 A study of carbon-concentrating mechanism-related gene expression revealed that the levels of mRNAs, such as CAH1, LCIB and HLA3, were significantly downregulated. Carbon 11-17 uncharacterized protein Chlamydomonas reinhardtii 109-113 28541935-5 2017 A study of carbon-concentrating mechanism-related gene expression revealed that the levels of mRNAs, such as CAH1, LCIB and HLA3, were significantly downregulated. Carbon 11-17 uncharacterized protein Chlamydomonas reinhardtii 115-119 19222267-9 2009 The efficiency and accuracy of our AO-MP2 method is demonstrated for linear alkanes, stacked DNA base pairs, and carbon nanotubes: e.g., for DNA systems the crossover toward conventional MP2 schemes occurs between one and two base pairs. Carbon 113-119 tryptase pseudogene 1 Homo sapiens 38-41 28393942-0 2017 Spin filtering with poly-T wrapped single wall carbon nanotubes. Carbon 47-53 spindlin 1 Homo sapiens 0-4 28156095-5 2017 In total, seven candidate TSPO tracers were synthesized and vetted in this study; the most promising tracer identified (29, Kd = 0.19 nM) was the result of conjugating a high-affinity TSPO ligand to a fluorophore used routinely in biological sciences (FITC) via a functional carbon linker of optimal length. Carbon 275-281 translocator protein Homo sapiens 26-30 23843601-0 2013 The role of carbon nanofiber defects on the electrical and mechanical properties of CNF-based resins. Carbon 12-18 NPHS1 adhesion molecule, nephrin Homo sapiens 84-87 23843601-2 2013 It affects the bonding states of carbon atoms in the nanofiber structure and causes a significant transformation in the hybridization state of the bonded carbon atoms.Nanofilled resins made of heat-treated CNF show significant increases in their electrical conductivity even at low concentrations. Carbon 33-39 NPHS1 adhesion molecule, nephrin Homo sapiens 206-209 23843601-2 2013 It affects the bonding states of carbon atoms in the nanofiber structure and causes a significant transformation in the hybridization state of the bonded carbon atoms.Nanofilled resins made of heat-treated CNF show significant increases in their electrical conductivity even at low concentrations. Carbon 154-160 NPHS1 adhesion molecule, nephrin Homo sapiens 206-209 23325705-3 2013 The biosensor is fabricated through the co-immobilization of GOx and the Os-RP on the surface of a glassy carbon electrode by a simple one-step chemical crosslinking process. Carbon 106-112 hydroxyacid oxidase 1 Homo sapiens 61-64 28156095-5 2017 In total, seven candidate TSPO tracers were synthesized and vetted in this study; the most promising tracer identified (29, Kd = 0.19 nM) was the result of conjugating a high-affinity TSPO ligand to a fluorophore used routinely in biological sciences (FITC) via a functional carbon linker of optimal length. Carbon 275-281 translocator protein Homo sapiens 184-188 19222267-9 2009 The efficiency and accuracy of our AO-MP2 method is demonstrated for linear alkanes, stacked DNA base pairs, and carbon nanotubes: e.g., for DNA systems the crossover toward conventional MP2 schemes occurs between one and two base pairs. Carbon 113-119 tryptase pseudogene 1 Homo sapiens 187-190 19132842-0 2009 Interaction of D-amino acid oxidase with carbon nanotubes: implications in the design of biosensors. Carbon 41-47 D-amino acid oxidase Homo sapiens 15-35 28413446-3 2017 We down-regulated the expression of phosphoenolpyruvate carboxylase (PEPC), which catalyzes the formation of oxaloacetate from phosphoenolpyruvate and regulates carbon flux. Carbon 161-167 uncharacterized protein Chlamydomonas reinhardtii 36-67 28413446-3 2017 We down-regulated the expression of phosphoenolpyruvate carboxylase (PEPC), which catalyzes the formation of oxaloacetate from phosphoenolpyruvate and regulates carbon flux. Carbon 161-167 uncharacterized protein Chlamydomonas reinhardtii 69-73 23747226-2 2013 Compound 3, where the substrate C-9 oxygen was replaced with a nonlabile CH2 group, inhibits HDHD4 with a binding affinity (IC50 11muM) in the range of the native substrate Neu5Ac-9-P (compound 1, Km 47muM). Carbon 0-1 N-acetylneuraminic acid phosphatase Homo sapiens 93-98 19132842-1 2009 We have investigated the interaction of d-amino acid oxidase (DAAO) with single-walled carbon nanotubes (CNT) by spectroscopic ellipsometry. Carbon 87-93 D-amino acid oxidase Homo sapiens 40-60 19132842-1 2009 We have investigated the interaction of d-amino acid oxidase (DAAO) with single-walled carbon nanotubes (CNT) by spectroscopic ellipsometry. Carbon 87-93 D-amino acid oxidase Homo sapiens 62-66 23921124-2 2013 Using an integrated genomics and 13C-based targeted tracer fate association (TTFA) study, we found that NRF2 regulates miR-1 and miR-206 to direct carbon flux toward the pentose phosphate pathway (PPP) and the tricarboxylic acid (TCA) cycle, reprogramming glucose metabolism. Carbon 147-153 microRNA 206 Mus musculus 129-136 28265606-2 2017 Glassy carbon electrodes were used to show that Pu(iv) and Pu(vi) complexes display a reversible electrochemical reduction wave in TBP previously equilibrated with aqueous nitric acid solution. Carbon 7-13 TATA-box binding protein Homo sapiens 131-134 19188831-5 2009 The inhibition constant of C-547 on cardiac AChE is 40-fold higher than that on extensor digitorum longus muscle AChE. Carbon 27-28 acetylcholinesterase Rattus norvegicus 44-48 23567548-5 2013 Poly(I:C) up-regulated pro-inflammatory cytokines, including TNF-alpha and IL-6, and type I interferons (IFN-alpha/beta). Carbon 7-8 interferon alpha Mus musculus 105-114 23439872-4 2013 Strain-dependent down-regulation of several key one-carbon metabolism genes, including methionine adenosyltransferase 1alpha (Mat1a), cystathionine-beta-synthase (Cbs), methylenetetrahydrofolate reductase (Mthfr), adenosyl-homocysteinase (Ahcy), and methylenetetrahydrofolate dehydrogenase 1 (Mthfd1), was observed. Carbon 52-58 methionine adenosyltransferase I, alpha Mus musculus 126-131 28096310-8 2017 Taken together, the data reported herein demonstrate that C. jejuni 81116 utilizes five enzymes to synthesize dTDP-Fuc3N or dTDP-Qui3N and that WlaRG, an aminotransferase, can function on sugars with differing stereochemistry about their C-4" carbons. Carbon 243-250 TAR DNA-binding protein-43 homolog Drosophila melanogaster 110-114 19188831-5 2009 The inhibition constant of C-547 on cardiac AChE is 40-fold higher than that on extensor digitorum longus muscle AChE. Carbon 27-28 acetylcholinesterase Rattus norvegicus 113-117 19084825-2 2009 Further increase in solution pH results in the deprotonation of OH-groups adjacent to C-2 and C-3 carbon atoms of beta-CD glucopyranose units, whereas the deprotonation of OH-groups adjacent to C-6 carbon atoms is expressed less markedly. Carbon 98-104 complement C2 Homo sapiens 86-97 28130714-9 2017 Nephrectomy significantly decreased sKL level [709.8 (599.9-831.2) vs. 583.0 (411.7-752.6) pg/ml, p < 0.001] and did not change c-FGF-23 concentration [70.5 (49.8-103.3) vs. 77.1 (60.5-109.1) RU/ml, p = 0.9]. Carbon 6-7 fibroblast growth factor 23 Homo sapiens 133-139 23475967-3 2013 In the course of a systematic screening of regulation targets of DNA-binding transcription factors from E. coli, we realized that CRP (cyclic AMP [cAMP] receptor protein), the global regulator for carbon source utilization, participates in regulation of some ribosomal protein genes, including the rmf gene. Carbon 197-203 catabolite gene activator protein Escherichia coli 130-133 23634906-10 2013 The serum levels of adiponectin in the CF, T and TF groups were lower than in the C group (41%; 34% and 31%, respectively). Carbon 39-40 adiponectin, C1Q and collagen domain containing Rattus norvegicus 20-31 28153281-0 2017 Highly sensitive amperometric detection of cardiac troponin I using sandwich aptamers and screen-printed carbon electrodes. Carbon 105-111 troponin I3, cardiac type Homo sapiens 43-61 18485589-0 2009 Use of adsorption using granular activated carbon (GAC) for the enhancement of removal of chromium from synthetic wastewater by electrocoagulation. Carbon 43-49 glutaminase Homo sapiens 51-54 28153281-1 2017 In this study, we developed a sandwich aptamer-based screen-printed carbon electrode (SPCE) using chronoamperometry for the detection of cardiac troponin I (cTnI), one of the promising biomarkers for acute myocardial infarction (AMI). Carbon 68-74 troponin I3, cardiac type Homo sapiens 137-155 28153281-1 2017 In this study, we developed a sandwich aptamer-based screen-printed carbon electrode (SPCE) using chronoamperometry for the detection of cardiac troponin I (cTnI), one of the promising biomarkers for acute myocardial infarction (AMI). Carbon 68-74 troponin I3, cardiac type Homo sapiens 157-161 28377773-5 2017 Our aim is to construct a model framework of tree growth for replacing current formulations in Dynamic Global Vegetation Models, and so address the issue of the terrestrial carbon sink. Carbon 173-179 tribbles pseudokinase 3 Homo sapiens 180-184 23417895-2 2013 The molecular mechanisms by which these dietary PUFA affect health involve the enrichment of cellular membranes with long-chain 20- and 22-carbon omega-3 PUFA that impacts tissues by altering membrane protein functions, cell signaling, and gene expression profiles. Carbon 139-145 pumilio RNA binding family member 3 Homo sapiens 48-52 23417895-2 2013 The molecular mechanisms by which these dietary PUFA affect health involve the enrichment of cellular membranes with long-chain 20- and 22-carbon omega-3 PUFA that impacts tissues by altering membrane protein functions, cell signaling, and gene expression profiles. Carbon 139-145 pumilio RNA binding family member 3 Homo sapiens 154-158 23208101-2 2013 Then, a high performance biosensor has been constructed by effectively attaching the proposed GOx-Au-PDA-Fe3O4 MBNPs to the surface of the magnetic glassy carbon electrode. Carbon 155-161 hydroxyacid oxidase 1 Homo sapiens 94-97 23228495-2 2013 The CNF electrode outperforms the conventional glassy carbon electrode (GCE) for both selectivity and sensitivity. Carbon 54-60 NPHS1 adhesion molecule, nephrin Homo sapiens 4-7 28326038-6 2017 The main metabolic soft spots of GAA were 3, 7, 11, 15, 23-carbonyl groups (or hydroxyl groups) and 12, 20, 28 (29)-carbon atoms. Carbon 59-65 alpha glucosidase Rattus norvegicus 33-36 18485589-1 2009 The present work deals with removal of hexavalent chromium from synthetic effluents in a batch stirred electrocoagulation cell with iron-aluminium electrode pair coupled with adsorption using granular activated carbon (GAC). Carbon 211-217 glutaminase Homo sapiens 219-222 19209591-0 2009 Carbon and chlorine isotope fractionation during aerobic oxidation and reductive dechlorination of vinyl chloride and cis-1,2-dichloroethene. Carbon 0-6 cytokine inducible SH2 containing protein Homo sapiens 118-123 23396334-3 2013 In previous studies, the complete redirection of the carbon flux toward the PPP by chromosomal inactivation of the pgi gene, encoding the phosphoglucoisomerase, has been applied for the improvement of C. glutamicum amino acid production strains, but this was accompanied by severe negative effects on the growth characteristics. Carbon 53-59 glucose-6-phosphate isomerase Corynebacterium glutamicum ATCC 13032 115-118 22213190-9 2013 The downregulation of Mat1a and Mthfr genes was accompanied by marked functional alterations in one-carbon metabolism. Carbon 100-106 methionine adenosyltransferase 1A Rattus norvegicus 22-27 28118570-3 2017 The electrochemical sensors based on PIL-Fe3O4-modified glassy carbon electrode were fabricated, and each of these nanocomposites was examined for the ability to determine amlodipine besylate (AMD). Carbon 63-69 serpin family A member 2 (gene/pseudogene) Homo sapiens 37-40 18683246-1 2009 We have previously reported that polyinosinic-polycytidylic acids [poly(I:C)], a synthetic toll-like receptor 3 (TLR3) agonist, induce Schwann cell activation, which exerts neurotoxic effects on sensory neurons. Carbon 74-75 toll-like receptor 3 Rattus norvegicus 91-111 28231328-0 2017 Integrating the SD-CLUE-S and InVEST models into assessment of oasis carbon storage in northwestern China. Carbon 69-75 cAMP responsive element binding protein 3 like 1 Homo sapiens 63-68 28231328-4 2017 The InVEST model was then used to simulate land-use change impacts on carbon storage at different scales in the oasis. Carbon 70-76 cAMP responsive element binding protein 3 like 1 Homo sapiens 112-117 23083908-0 2013 Carbon nanotubes-nanoflake-like SnS2 nanocomposite for direct electrochemistry of glucose oxidase and glucose sensing. Carbon 0-6 hydroxyacid oxidase 1 Homo sapiens 82-97 23083908-1 2013 Multi-walled carbon nanotubes (MWCNTs)-nanoflake-like SnS(2) nanocomposite were designed for immobilization of glucose oxidase (GOx). Carbon 13-19 hydroxyacid oxidase 1 Homo sapiens 111-126 23083908-1 2013 Multi-walled carbon nanotubes (MWCNTs)-nanoflake-like SnS(2) nanocomposite were designed for immobilization of glucose oxidase (GOx). Carbon 13-19 hydroxyacid oxidase 1 Homo sapiens 128-131 23098855-2 2013 Glucose oxidase (GOx) was immobilized on GQD modified carbon ceramic electrode (CCE) and well-defined quasi-reversible redox peaks were observed. Carbon 54-60 hydroxyacid oxidase 1 Homo sapiens 0-15 18683246-1 2009 We have previously reported that polyinosinic-polycytidylic acids [poly(I:C)], a synthetic toll-like receptor 3 (TLR3) agonist, induce Schwann cell activation, which exerts neurotoxic effects on sensory neurons. Carbon 74-75 toll-like receptor 3 Rattus norvegicus 113-117 23098855-2 2013 Glucose oxidase (GOx) was immobilized on GQD modified carbon ceramic electrode (CCE) and well-defined quasi-reversible redox peaks were observed. Carbon 54-60 hydroxyacid oxidase 1 Homo sapiens 17-20 28231328-5 2017 The results showed that: (1) the effects of built-up land expansion were especially notable, with a rapid decrease in cropland during 2009-2018; (2) the strict protection scenario saved the largest amount of carbon storage for the oasis compared with the current trend and moderate protection scenarios. Carbon 208-214 cAMP responsive element binding protein 3 like 1 Homo sapiens 231-236 19049427-2 2008 To overcome the unwanted inhibition of the hepatic enzyme CYP1A2, we aimed at reducing the number of aromatic carbons of these molecules because aromaticity has previously been identified to correlate positively with CYP1A2 inhibition. Carbon 110-117 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 58-64 27899380-2 2017 Indeed, one of the most highly upregulated enzymes during neoplastic transformation is MTHFD2, a mitochondrial methylenetetrahydrofolate dehydrogenase and cyclohydrolase involved in one-carbon metabolism. Carbon 186-192 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 87-93 23507534-2 2013 In particular removal of adenine from A:8-oxodG mispairs by MUTYH activity is followed by error-free base excision repair (BER) events, leading to the formation of C:8-oxodG base pairs. Carbon 164-165 mutY DNA glycosylase Homo sapiens 60-65 19049427-2 2008 To overcome the unwanted inhibition of the hepatic enzyme CYP1A2, we aimed at reducing the number of aromatic carbons of these molecules because aromaticity has previously been identified to correlate positively with CYP1A2 inhibition. Carbon 110-117 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 217-223 21581532-1 2008 In the title complex, [Mn(C(27)H(24)Br(3)N(4)O(3))], the Mn(III) ion is six-coordinated in a distorted octa-hedral environment by three N atoms and three O atoms from the trianion of the hexa-dentate ligand tris-[2-(5-bromo-2-oxidobenzyl-idene-amino)eth-yl]amine. Carbon 26-27 hexosaminidase subunit alpha Homo sapiens 187-191 23289639-0 2013 Influence of surface adsorption on the interfacial electron transfer of flavin adenine dinucleotide and glucose oxidase at carbon nanotube and nitrogen-doped carbon nanotube electrodes. Carbon 123-129 hydroxyacid oxidase 1 Homo sapiens 104-119 23289639-1 2013 The adsorption of flavin adenine dinucleotide (FAD) and glucose oxidase (GOx) onto carbon nanotube (CNT) and nitrogen-doped CNT (N-CNT) electrodes was investigated and found to obey Langmuir adsorption isotherm characteristics. Carbon 83-89 hydroxyacid oxidase 1 Homo sapiens 56-71 23289639-1 2013 The adsorption of flavin adenine dinucleotide (FAD) and glucose oxidase (GOx) onto carbon nanotube (CNT) and nitrogen-doped CNT (N-CNT) electrodes was investigated and found to obey Langmuir adsorption isotherm characteristics. Carbon 83-89 hydroxyacid oxidase 1 Homo sapiens 73-76 27821334-1 2017 In this paper, the spherical Au nanoparticles and 3D flower-like structure graphene were successively deposited on glassy carbon electrode (GCE) (Au/f-GE/GCE) via a facile and two-step electrodeposition method for the detection of nitrite ions (NaNO2). Carbon 122-128 sulfatase modifying factor 1 Homo sapiens 149-153 28336872-1 2017 In this study, a biosensor, based on a glucose oxidase (GOx) immobilized, carbon-coated tin sulfide (SnS) assembled on a glass carbon electrode (GCE) was developed, and its direct electrochemistry was investigated. Carbon 74-80 hydroxyacid oxidase 1 Homo sapiens 39-54 28336872-1 2017 In this study, a biosensor, based on a glucose oxidase (GOx) immobilized, carbon-coated tin sulfide (SnS) assembled on a glass carbon electrode (GCE) was developed, and its direct electrochemistry was investigated. Carbon 74-80 hydroxyacid oxidase 1 Homo sapiens 56-59 27008387-6 2013 There were significant differences in water chemistry variables between oasis and northern sites, with oasis sites having higher conductivity and greater concentrations of nutrients and related variables such as dissolved organic carbon (DOC). Carbon 230-236 cAMP responsive element binding protein 3 like 1 Homo sapiens 103-108 19002333-0 2008 A mechanistic study of the C-P bond cleavage reaction of 1,2-(PH2)2-C6H4 with nBuLi/Sb(NMe2)3. Carbon 27-28 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 87-91 23207903-1 2013 Adr1 and Cat8 are nutrient-regulated transcription factors in Saccharomyces cerevisiae that coactivate genes necessary for growth in the absence of a fermentable carbon source. Carbon 162-168 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 0-4 23221678-1 2013 Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme of the tetrahydrofolate (THF)-mediated one-carbon (C1) metabolic network. Carbon 103-109 probable methylenetetrahydrofolate reductase Nicotiana tabacum 0-35 23221678-1 2013 Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme of the tetrahydrofolate (THF)-mediated one-carbon (C1) metabolic network. Carbon 103-109 probable methylenetetrahydrofolate reductase Nicotiana tabacum 37-42 27882495-7 2017 The contents of total organic carbon are moderately correlated with BDE-209 concentrations in sediments but not with 9PBDE concentrations. Carbon 30-36 homeobox D13 Homo sapiens 68-71 18971323-3 2008 U6 snRNPs, purified by affinity chromatography and gradient centrifugation, and then immediately adsorbed to the carbon film support, revealed an open form in which the Prp24 protein and the ring formed by the LSm proteins were visible as two separate morphological domains, while particles stabilized by chemical cross-linking in solution under mild conditions before binding to the carbon film exhibited a compact form, with the two domains in close proximity to one another. Carbon 113-119 U6 snRNP complex subunit PRP24 Saccharomyces cerevisiae S288C 169-174 28166932-6 2017 Porcine PBMCs bind to Poly (I:C)-treated cells and this binding is dependent on HA, since the increase in adhesion is abolished by hyaluronidase treatment of the cell layers. Carbon 30-32 hemopexin Sus scrofa 131-144 23359425-4 2013 To address this possibility, we overexpressed the ERR2 and ERR3 genes individually in a double-null yeast strain lacking ENO1 and ENO2, and showed that either ERR2 or ERR3 could complement the growth defect in this strain when cells are grown in medium with glucose as the carbon source. Carbon 273-279 phosphopyruvate hydratase ERR2 Saccharomyces cerevisiae S288C 50-54 23359425-4 2013 To address this possibility, we overexpressed the ERR2 and ERR3 genes individually in a double-null yeast strain lacking ENO1 and ENO2, and showed that either ERR2 or ERR3 could complement the growth defect in this strain when cells are grown in medium with glucose as the carbon source. Carbon 273-279 phosphopyruvate hydratase ERR2 Saccharomyces cerevisiae S288C 159-163 23311980-3 2013 PEPCK offers a route, alternative to pyruvate kinase, for carbon skeletons to move between cytosolic glycolysis and mitochondrial Krebs cycle reactions. Carbon 58-64 Pyruvate kinase Drosophila melanogaster 37-52 18989861-0 2008 Polarization dependence of the C 1s X-ray absorption spectra of individual multi-walled carbon nanotubes. Carbon 88-94 heterogeneous nuclear ribonucleoprotein C Homo sapiens 31-34 23662055-0 2013 Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis. Carbon 60-66 interleukin 33 Mus musculus 133-138 23662055-0 2013 Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis. Carbon 60-66 interleukin 1 receptor-like 1 Mus musculus 139-142 28137282-7 2017 Therefore, we explored dynamic control of ERG20 expression to redistribute the precursor geranyl diphosphate flux and achieved a 3.4-fold increase in geraniol production after optimizing carbon source feeding. Carbon 187-193 bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase Saccharomyces cerevisiae S288C 42-47 18921987-1 2008 Photochemical properties of p-phenylphenacyl derivatives (PP-X) having C-halide, C-S, and C-O bonds in the lowest (T 1) and higher (T n ) triplet excited states were investigated in solution by using single-color and stepwise two-color two-laser flash photolysis techniques. Carbon 71-72 protein phosphatase 4 catalytic subunit Homo sapiens 58-62 28143980-16 2017 Here the transcription factor Cst6/Rca1 controls carbon homeostasis by regulating carbonic anhydrase expression. Carbon 49-55 Cst6p Saccharomyces cerevisiae S288C 30-34 28143980-16 2017 Here the transcription factor Cst6/Rca1 controls carbon homeostasis by regulating carbonic anhydrase expression. Carbon 49-55 m-AAA protease subunit YTA12 Saccharomyces cerevisiae S288C 35-39 23127906-9 2013 Allele DGAT1 232A in winter as well as in summer milk samples was negatively associated with most FA with less than 18 carbons, saturated FA, saturated FA to unsaturated FA ratio, and C10 to C16 unsaturation indices, and was positively associated with C14:0, unsaturated C18, unsaturated FA, and C18 and conjugated linoleic acid unsaturation indices. Carbon 119-126 diacylglycerol O-acyltransferase 1 Bos taurus 7-12 25464705-7 2013 The Carbon Preference Index for alkanes between C25 and C33 was greater than one and less than three, indicating anthropogenic sources like petroleum hydrocarbons. Carbon 4-10 CD82 molecule Homo sapiens 56-59 28051307-0 2017 Highly Efficient Magnetic Nitrogen-Doped Porous Carbon Prepared by One-Step Carbonization Strategy for Hg2+ Removal from Water. Carbon 48-54 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 103-106 18844342-1 2008 The reaction of [Pt(dmba)(PPh3)Cl] [where dmba = N,C-chelating 2-(dimethylaminomethyl)phenyl] with aqueous ammonia in acetone in the presence of AgClO4 gives the acetonimine complex [Pt(dmba)(PPh3)(NH=CMe2)]ClO4 (1). Carbon 31-32 protein phosphatase 4 catalytic subunit Homo sapiens 26-30 27769942-0 2017 Carbon nanotube-composite hydrogels promote intercalated disc assembly in engineered cardiac tissues through beta1-integrin mediated FAK and RhoA pathway. Carbon 0-6 integrin subunit beta 1 Homo sapiens 109-123 23646703-8 2013 We report for the first time in the fabrication of carbon paste bioelectrode containing magnetite-chitosan-GOx. Carbon 51-57 hydroxyacid oxidase 1 Homo sapiens 107-110 18778798-9 2008 The long chain dicholine ester makes closer contact than the short chain ester between one of its carbonyl carbons and the catalytic Ser198, thus explaining why long-chain dicholine esters are hydrolyzed more rapidly by butyrylcholinesterase. Carbon 107-114 butyrylcholinesterase Homo sapiens 220-241 23535662-5 2013 Here, we find that yeast SCF (Skp1-Cdc53-F-box) Cullin-RING complexes are remodelled in a CAND1-dependent manner, when cells are switched from growth in fermentable to non-fermentable carbon sources. Carbon 184-190 KIT ligand Canis lupus familiaris 25-28 28098753-3 2017 In this work, we developed a lactate biosensor based on the immobilization of lactate oxidase (LOx) onto N,N"-Bis(3,4-dihydroxybenzylidene) -1,2-diaminobenzene Schiff base tetradentate ligand-modified gold nanoparticles (3,4DHS-AuNPs) deposited onto screen-printed carbon electrodes, which exhibit a potent electrocatalytic effect towards hydrogen peroxide oxidation/reduction. Carbon 265-271 lysyl oxidase Homo sapiens 78-93 28098753-3 2017 In this work, we developed a lactate biosensor based on the immobilization of lactate oxidase (LOx) onto N,N"-Bis(3,4-dihydroxybenzylidene) -1,2-diaminobenzene Schiff base tetradentate ligand-modified gold nanoparticles (3,4DHS-AuNPs) deposited onto screen-printed carbon electrodes, which exhibit a potent electrocatalytic effect towards hydrogen peroxide oxidation/reduction. Carbon 265-271 lysyl oxidase Homo sapiens 95-98 28098753-6 2017 Lactate oxidase (LOx) catalyzes the conversion of l-lactate to pyruvate in the presence of oxygen, producing hydrogen peroxide, which is catalytically oxidized at 3,4DHS-AuNPs modified screen-printed carbon electrodes at +0.2 V. The measured electrocatalytic current is directly proportional to the concentration of peroxide, which is related to the amount of lactate present in the sample. Carbon 200-206 lysyl oxidase Homo sapiens 0-15 28098753-6 2017 Lactate oxidase (LOx) catalyzes the conversion of l-lactate to pyruvate in the presence of oxygen, producing hydrogen peroxide, which is catalytically oxidized at 3,4DHS-AuNPs modified screen-printed carbon electrodes at +0.2 V. The measured electrocatalytic current is directly proportional to the concentration of peroxide, which is related to the amount of lactate present in the sample. Carbon 200-206 lysyl oxidase Homo sapiens 17-20 28027722-4 2017 Celastrol significantly inhibited poly(I:C)-induced expression of adhesion molecules, such as ICAM-1/VCAM-1, and chemokines, such as CCL2, CXCL8, and CXCL10, in CRT-MG human astroglioma cells. Carbon 0-1 intercellular adhesion molecule 1 Homo sapiens 94-100 28027722-4 2017 Celastrol significantly inhibited poly(I:C)-induced expression of adhesion molecules, such as ICAM-1/VCAM-1, and chemokines, such as CCL2, CXCL8, and CXCL10, in CRT-MG human astroglioma cells. Carbon 0-1 C-X-C motif chemokine ligand 10 Homo sapiens 150-156 23251905-7 2012 To elucidate the regulatory links between virulence and carbon metabolism, we performed comparative metabolome, transcriptome, and phenotypic microarray analyses and found that Crp promotes oxidative catabolism of many different carbon sources, whereas fermentative patterns of metabolism are favored when crp is deleted. Carbon 56-62 C-reactive protein, pentraxin-related Mus musculus 177-180 23251905-7 2012 To elucidate the regulatory links between virulence and carbon metabolism, we performed comparative metabolome, transcriptome, and phenotypic microarray analyses and found that Crp promotes oxidative catabolism of many different carbon sources, whereas fermentative patterns of metabolism are favored when crp is deleted. Carbon 229-235 C-reactive protein, pentraxin-related Mus musculus 177-180 19137722-0 2008 [Microbial processes of the carbon and sulfur cycles in the White Sea]. Carbon 28-34 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 66-69 22975425-1 2012 The reconstitution of apo-glucose oxidase (apo-GOx) on single-walled carbon nanotubes (SWNTs) functionalized with the cofactor, flavin adenine dinucleotide (FAD), greatly improved electron transfer turnover rate of the redox reactions in glucose sensing with glucose sensors. Carbon 69-75 hydroxyacid oxidase 1 Homo sapiens 47-50 23153812-4 2012 The substituent on the alpha-carbon to the N1-hydrazine moiety (methyl or hydrogen) had a great influence on the activity and hMAO-B selectivity. Carbon 29-35 monoamine oxidase B Homo sapiens 126-132 19137722-11 2008 We demonstrated that the rates of microbial processes of the carbon and sulfur cycles occurring in the sediments of the White Sea basin were low. Carbon 61-67 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 126-129 27871380-0 2017 An improved amperometric L-lactate biosensor based on covalent immobilization of microbial lactate oxidase onto carboxylated multiwalled carbon nanotubes/copper nanoparticles/polyaniline modified pencil graphite electrode. Carbon 137-143 lysyl oxidase Homo sapiens 91-106 27871380-1 2017 An improved amperometric l-lactate biosensor was constructed based on covalent immobilization of lactate oxidase (LOx) from Pediococcus species onto carboxylated multiwalled carbon nanotubes (cMWCNT)/copper nanoparticles (CuNPs)/polyaniline (PANI) hybrid film electrodeposited on the surface of a pencil graphite electrode (PGE). Carbon 174-180 lysyl oxidase Homo sapiens 114-117 18937227-4 2008 Various configurations of B5C clusters containing three-membered boron rings have predominance in energy, whereas various configurations of C5B clusters containing three-membered carbon rings are disadvantageous in energy. Carbon 179-185 complement C5 Homo sapiens 140-143 30460304-1 2017 We report an electrodeposited poly(pyrrole-co-pyrrolepropylic acid) copolymer modified electroactive graphene-carbon nanotubes composite deposited on a glassy carbon electrode to detect the protein antigen (cTnI). Carbon 110-116 troponin I3, cardiac type Homo sapiens 207-211 22973045-7 2012 We found that the poly(I:C)-induced initial phosphorylation of STAT1 is dependent on the RIG-I pathway and that MDA-5 is not involved in STAT1 phosphorylation. Carbon 25-27 signal transducer and activator of transcription 1 Homo sapiens 63-68 22973045-7 2012 We found that the poly(I:C)-induced initial phosphorylation of STAT1 is dependent on the RIG-I pathway and that MDA-5 is not involved in STAT1 phosphorylation. Carbon 25-27 DExD/H-box helicase 58 Homo sapiens 89-94 18713766-9 2008 Activation of PPARalpha by PFAA carboxylates was positively correlated with carbon chain length, up to C9. Carbon 76-82 peroxisome proliferator activated receptor alpha Homo sapiens 14-23 22842019-8 2012 Nda2 is therefore important for linking H2 photoproduction with catabolism of storage carbon compounds, and seems also involved in regulating the redox poise of the photosynthetic electron transport chain during H2 photoproduction. Carbon 86-92 uncharacterized protein Chlamydomonas reinhardtii 0-4 23092968-1 2012 We demonstrate the fabrication of hybrid nanocomposite electrodes with a combination of SnO(2) nanoparticles (NPs) and conducting multiwalled carbon nanotube (MWCNT) anodes (SnO(2)@CNT) through the direct anchoring of SnO(2) NPs on the surface of electrophoretically pre-deposited MWCNT (EPD-CNT) networks via a metal-organic chemical vapor deposition process. Carbon 142-148 strawberry notch homolog 2 Homo sapiens 174-177 27993762-4 2016 OBJECTIVE: The objective of the study is to identify, describe the features, and rate the quality of existing smartphone apps which capture personal travel and dietary behavior and simultaneously estimate the carbon cost and potential health consequences of these actions. Carbon 209-215 cathepsin B Homo sapiens 121-125 27993762-6 2016 Eligible apps were required to estimate the carbon cost of personal behaviors with the potential to include features to maximize health outcomes. Carbon 44-50 cathepsin B Homo sapiens 9-13 27572526-0 2016 Water soluble organic carbon in aerosols (PM1, PM2.5, PM10) and various precipitation forms (rain, snow, mixed) over the southern Baltic Sea station. Carbon 22-28 transmembrane protein 11 Homo sapiens 42-45 18713766-12 2008 We conclude that, in general, (1) PFAAs of increasing carbon backbone chain lengths induce increasing activity of the mouse and human PPARalpha with a few exceptions, (2) PFAA carboxylates are stronger activators of mouse and human PPARalpha than PFAA sulfonates, and (3) in most cases, the mouse PPARalpha appears to be more sensitive to PFAAs than the human PPARalpha in this model. Carbon 54-60 peroxisome proliferator activated receptor alpha Homo sapiens 134-143 27572526-6 2016 On the other hand, the highest WSOC concentrations in PM1 occurred in winter at low air temperatures and greatest atmospheric stability, when there were increased carbon emissions from fuel combustion in the communal-utility sector and from transportation. Carbon 163-169 transmembrane protein 11 Homo sapiens 54-57 18837492-5 2008 Four energetically accessible reaction routes are revealed, i.e., the decomposition of the nitrite adduct forming C 2Cl 3O + NO and its sequential dissociation to CO + NO + CCl 3, the elimination of ClNO from the nitrite adduct leading to ClNO + Cl 2CCO, the Cl-atom shift of the nitrite adduct followed by the decomposition to CCl 3CO + NO, and the O-atom shift of the nitro adduct followed by C-C bond cleavage forming ClCNO + Cl 2CO. Carbon 114-115 C-C motif chemokine ligand 3 Homo sapiens 173-178 27936032-0 2016 The RFC1 80G>A, among Common One-Carbon Polymorphisms, Relates to Survival Rate According to DNA Global Methylation in Primary Liver Cancers. Carbon 36-42 replication factor C subunit 1 Homo sapiens 4-8 27634155-3 2016 The proposed removal mechanism included the adsorption of BDE 209 on the surface or interior of the biomass carbon NZVI (BC-NZVI) particles and the subsequent debromination of BDE 209 by NZVI while biomass carbon served as an electron shuttle. Carbon 206-212 homeobox D13 Homo sapiens 58-61 27634155-3 2016 The proposed removal mechanism included the adsorption of BDE 209 on the surface or interior of the biomass carbon NZVI (BC-NZVI) particles and the subsequent debromination of BDE 209 by NZVI while biomass carbon served as an electron shuttle. Carbon 206-212 homeobox D13 Homo sapiens 176-179 27687053-2 2016 DNA methylation is catalysed by DNA methyltransferase (DNMT) enzymes, which are responsible for the addition of a methyl group to the fifth carbon atom of the cytosine residues within cytosine-phosphate-guanine (CpG) and non-CpG dinucleotide sites. Carbon 140-146 DNA methyltransferase 1 Homo sapiens 32-53 27687053-2 2016 DNA methylation is catalysed by DNA methyltransferase (DNMT) enzymes, which are responsible for the addition of a methyl group to the fifth carbon atom of the cytosine residues within cytosine-phosphate-guanine (CpG) and non-CpG dinucleotide sites. Carbon 140-146 DNA methyltransferase 1 Homo sapiens 55-59 27759368-4 2016 This article proposes a novel architecture of Sb-doped SnO2 nanoparticles sandwiched between carbon nanofiber and carbon skin (CNF/ATO/C) using electrospinning and hydrothermal methods. Carbon 114-120 NPHS1 adhesion molecule, nephrin Homo sapiens 127-130 27767295-6 2016 The study explains the progress of increasing capacity of C@SnS/SnO2@CNFs and likewise provides a perspective on optimization of the electrochemical performance of electrodes. Carbon 58-59 strawberry notch homolog 2 Homo sapiens 64-67 27806131-4 2016 PrkA was required for resistance to cell wall stress, growth on cytosolic carbon sources, intracellular replication, cytosolic survival, inflammasome avoidance and ultimately virulence in a murine model of Listeriosis. Carbon 74-80 A kinase (PRKA) anchor protein 6 Mus musculus 0-4 26954224-2 2016 Elongation of very-long-chain fatty acids 1 (ELOVL1) is a ubiquitously expressed gene and the product of which was thought to be associated with elongation of carbon (C) chain in fatty acids. Carbon 159-169 ELOVL fatty acid elongase 1 Bos taurus 45-51 27061925-1 2016 The timing of the end of the vegetation growing season (EOS) plays a key role in terrestrial ecosystem carbon and nutrient cycles. Carbon 103-109 EOS Homo sapiens 56-59 27061925-8 2016 Our study, therefore, suggests that both environmental factors and spring phenology should be included in the modeling of EOS to improve the predictions of autumn phenology as well as our understanding of the global carbon and nutrient balances. Carbon 216-222 EOS Homo sapiens 122-125 27741250-7 2016 Further analyses revealed that interacting mutations in HOG1 and ISU1 unexpectedly elevated mitochondrial respiratory proteins and enabled rapid aerobic respiration of xylose and other non-fermentable carbon substrates. Carbon 201-207 iron-binding protein ISU1 Saccharomyces cerevisiae S288C 65-69 27698482-7 2016 In subjects with a first-degree FHD, only those with serum FGF23 levels in the upper quartile were more likely to have an increased C-IMT (odds ratio = 2.263, P < 0.05). Carbon 132-133 fibroblast growth factor 23 Homo sapiens 59-64 27486859-1 2016 The human dimethylglycine dehydrogenase (hDMGDH) is a flavin adenine dinucleotide (FAD)- and tetrahydrofolate (THF)-dependent, mitochondrial matrix enzyme taking part in choline degradation, one-carbon metabolism and electron transfer to the respiratory chain. Carbon 195-201 dimethylglycine dehydrogenase Homo sapiens 10-39 27486859-1 2016 The human dimethylglycine dehydrogenase (hDMGDH) is a flavin adenine dinucleotide (FAD)- and tetrahydrofolate (THF)-dependent, mitochondrial matrix enzyme taking part in choline degradation, one-carbon metabolism and electron transfer to the respiratory chain. Carbon 195-201 dimethylglycine dehydrogenase Homo sapiens 41-47 27314514-3 2016 The present study describes a novel metabolic engineering ploy involving the constitutive down-regulation of endogenous ADP-glucose pyrophosphorylase (BjAGPase) enzyme and the seed-specific expression of WRINKLED1 transcription factor (AtWRI1) from Arabidopsis thaliana in Indian mustard (Brassica juncea) with an aim to divert the photosynthetically fixed carbon pool from starch to lipid synthesis in the seeds for the enhanced production of storage lipids in the seeds of transgenic mustard plants. Carbon 357-363 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 204-213 27314514-3 2016 The present study describes a novel metabolic engineering ploy involving the constitutive down-regulation of endogenous ADP-glucose pyrophosphorylase (BjAGPase) enzyme and the seed-specific expression of WRINKLED1 transcription factor (AtWRI1) from Arabidopsis thaliana in Indian mustard (Brassica juncea) with an aim to divert the photosynthetically fixed carbon pool from starch to lipid synthesis in the seeds for the enhanced production of storage lipids in the seeds of transgenic mustard plants. Carbon 357-363 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 236-242 27578405-1 2016 The application of magnetized graphene (G) layers synthesized on the carbon nanofibers (CNFs) (m-G/CNF) was investigated as novel adsorbent for the magnetic solid-phase extraction (MSPE) of polycyclic aromatic hydrocarbons (PAHs) in water samples followed by gas chromatography-flame ionization detector (GC-FID). Carbon 69-75 NPHS1 adhesion molecule, nephrin Homo sapiens 88-91 27621627-0 2016 Defect density in multiwalled carbon nanotubes influences ovalbumin adsorption and promotes macrophage activation and CD4(+) T-cell proliferation. Carbon 30-36 CD4 antigen Mus musculus 118-121 27488260-2 2016 Functional polymorphisms in genes encoding choline-related one-carbon metabolism enzymes, including phosphatidylethanolamine N-methyltransferase (PEMT), choline dehydrogenase (CHDH) and betaine-homocysteine methyltransferase (BHMT), have important roles in choline metabolism and may thus interact with dietary choline and betaine intake to modify breast cancer risk. Carbon 63-69 choline dehydrogenase Homo sapiens 153-174 27504712-0 2016 MAP4K4 deficiency in CD4(+) T cells aggravates lung damage induced by ozone-oxidized black carbon particles. Carbon 91-97 mitogen-activated protein kinase kinase kinase kinase 4 Mus musculus 0-6 27504712-0 2016 MAP4K4 deficiency in CD4(+) T cells aggravates lung damage induced by ozone-oxidized black carbon particles. Carbon 91-97 CD4 antigen Mus musculus 21-24 27095432-10 2016 Epidermal Ki67 immunopositivity was significantly suppressed in B6.Cg-Tyr(c-2J) Hr(hr) /J mice at 24 h post-UV. Carbon 43-44 antigen identified by monoclonal antibody Ki 67 Mus musculus 10-14 27468646-4 2016 CAM treatment led to a significant reduction in poly I:C- and RSV-mediated IL-8, CCL5, IFN-beta and -lambda production. Carbon 0-1 C-C motif chemokine ligand 5 Homo sapiens 81-85 27486831-2 2016 These structures often differ at the C3a position, which may be substituted with an oxygen, nitrogen, or sp(3)- or sp(2)-hybridized carbon. Carbon 132-138 endogenous retrovirus group K member 2 Homo sapiens 37-40 27260448-0 2016 A sensitive and selective on-line amperometric sulfite biosensor using sulfite oxidase immobilized on a magnetite-gold-folate nanocomposite modified carbon-paste electrode. Carbon 149-155 sulfite oxidase Homo sapiens 71-86 27260448-1 2016 We describe a novel amperometric sulfite biosensor, comprising a carbon-paste electrode (Fe3O4@Au-Cys-FA/CPE) modified with immobilized sulfite oxidase (SOx) on a gold-coated magnetite nanoparticle core, encased within a conjugated folic acid (FA) cysteine (Cys) shell. Carbon 65-71 sulfite oxidase Homo sapiens 153-156 27132228-2 2016 Different carbon and nitrogen ratios have shown different growth rates and biomass productivity and C:N ratio 50:10 as mgL(-1) has shown the best production than all. Carbon 100-101 LLGL scribble cell polarity complex component 1 Homo sapiens 119-125 27173682-2 2016 C677T and A1298C MTHFR polymorphisms produce an enzyme with reduced folate-related one carbon metabolism, and this has been associated with aberrant methylation modifications in DNA and protein. Carbon 87-93 methylenetetrahydrofolate reductase Homo sapiens 17-22 27343244-4 2016 We now report that depriving cells of serine and glycine promotes RR formation, and we have traced these effects to dihydrofolate reductase (DHFR) and serine hydroxymethyltransferase-2 (SHMT2), pivotal enzymes in one-carbon metabolism and nucleotide biosynthesis. Carbon 217-223 serine hydroxymethyltransferase 2 Homo sapiens 151-184 27343244-4 2016 We now report that depriving cells of serine and glycine promotes RR formation, and we have traced these effects to dihydrofolate reductase (DHFR) and serine hydroxymethyltransferase-2 (SHMT2), pivotal enzymes in one-carbon metabolism and nucleotide biosynthesis. Carbon 217-223 serine hydroxymethyltransferase 2 Homo sapiens 186-191 27015375-9 2016 Carbon coverage and repeated thermal treatments during industrial processing also caused annealing of radiogenic hAl defects. Carbon 0-6 histidine ammonia-lyase Homo sapiens 113-116 27107972-8 2016 ELOVL5 and ELOVL6 mRNA levels were suggestive of overexpression of membrane phospholipids containing elongated fatty acids with 16, 18, and 20 carbons. Carbon 143-150 ELOVL fatty acid elongase 6 Bos taurus 11-17 27017073-3 2016 On haze days, accumulation of organic carbon (OC), elemental carbon (EC) and primary organic carbon (POC) in PM1-2.5 was faster than that in PM1. Carbon 38-44 transmembrane protein 11 Homo sapiens 109-112 27017073-3 2016 On haze days, accumulation of organic carbon (OC), elemental carbon (EC) and primary organic carbon (POC) in PM1-2.5 was faster than that in PM1. Carbon 61-67 transmembrane protein 11 Homo sapiens 109-112 27017073-3 2016 On haze days, accumulation of organic carbon (OC), elemental carbon (EC) and primary organic carbon (POC) in PM1-2.5 was faster than that in PM1. Carbon 61-67 transmembrane protein 11 Homo sapiens 109-112 27017073-4 2016 Humic-like substances carbon (Hulis-C) in both PM2.5 and PM1 formed faster than water soluble organic carbon (WSOC) on haze days, hence Hulis-C/WSOC increased with the intensification of haze pollution. Carbon 22-28 transmembrane protein 11 Homo sapiens 57-60 27350173-5 2016 Skeletal muscle mRNA expression of serine/one-carbon/glycine biosynthesis pathway genes (Phgdh, Psat1 and Psph) and the gluconeogenic enzyme, phosphoenolpyruvate carboxykinase-M (Pck2/PEPCK-M), increased during treatment with BA, and to a lesser extent GH (p < 0.001, treatment x time interaction). Carbon 46-52 phosphoserine phosphatase Sus scrofa 106-110 22918319-0 2012 Winter mass concentrations of carbon species in PM10, PM 2.5 and PM1 in Zagreb air, Croatia. Carbon 30-36 transmembrane protein 11 Homo sapiens 48-51 22475642-7 2012 The EP2 agonist significantly suppressed the polyI:C-induced expression of CCL5 (P < 0.005), CXCL10 (P < 0.0005), and CXCL11 (P < 0.05) but not of CCL20 and IL-6. Carbon 51-52 C-C motif chemokine ligand 5 Homo sapiens 75-79 22475642-7 2012 The EP2 agonist significantly suppressed the polyI:C-induced expression of CCL5 (P < 0.005), CXCL10 (P < 0.0005), and CXCL11 (P < 0.05) but not of CCL20 and IL-6. Carbon 51-52 C-X-C motif chemokine ligand 10 Homo sapiens 96-102 22475642-7 2012 The EP2 agonist significantly suppressed the polyI:C-induced expression of CCL5 (P < 0.005), CXCL10 (P < 0.0005), and CXCL11 (P < 0.05) but not of CCL20 and IL-6. Carbon 51-52 C-X-C motif chemokine ligand 11 Homo sapiens 124-130 22885800-3 2012 Tris(triphenylphosphine)rhodium(I) carbonyl hydride M(H)(CO)(PPh(3))(3) (M = Rh, Ir) cleaved one of the E-Me bonds of {o-(Ph(2)P)C(6)H(4)}(2)EMe(2) exclusively to afford the trigonal bipyramidal (TBP) complexes, [PEP]M(CO)(PPh(3)). Carbon 57-58 TATA-box binding protein Homo sapiens 196-199 23125802-2 2012 The N-H group attached to the exocyclic C=C bond is in a syn arrangement with respect to the C=O bond of the pyrazolone group and an intra-molecular N-H O hydrogen bond is observed. Carbon 40-41 synemin Homo sapiens 57-60 23125802-2 2012 The N-H group attached to the exocyclic C=C bond is in a syn arrangement with respect to the C=O bond of the pyrazolone group and an intra-molecular N-H O hydrogen bond is observed. Carbon 42-43 synemin Homo sapiens 57-60 23125802-2 2012 The N-H group attached to the exocyclic C=C bond is in a syn arrangement with respect to the C=O bond of the pyrazolone group and an intra-molecular N-H O hydrogen bond is observed. Carbon 42-43 synemin Homo sapiens 57-60 22935373-2 2012 The peptides with a sequence specific to c-Src tyrosine kinase and protein tyrosine phosphatase 1B (PTP1B) were first validated with ELISA-based protein tyrosine kinase assay and then functionalized on vertically aligned carbon nanofiber (VACNF) nanoelectrode arrays (NEAs). Carbon 221-227 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 67-98 22935373-2 2012 The peptides with a sequence specific to c-Src tyrosine kinase and protein tyrosine phosphatase 1B (PTP1B) were first validated with ELISA-based protein tyrosine kinase assay and then functionalized on vertically aligned carbon nanofiber (VACNF) nanoelectrode arrays (NEAs). Carbon 221-227 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 100-105 22777948-0 2012 A carbon nanotube toxicity paradigm driven by mast cells and the IL-33/ST2 axis. Carbon 2-8 ST2 Homo sapiens 71-74 22913607-4 2012 The C10 homologue was the most predominant carbon chain group, followed by C11, C12, and C13 homologue groups. Carbon 43-49 chromosome 12 open reading frame 57 Homo sapiens 4-7 22967516-1 2012 A mediatorless glucose biosensor was developed by the immobilization of glucose oxidase (GOx) to graphene-functionalized glassy carbon electrode (GCE). Carbon 128-134 hydroxyacid oxidase 1 Homo sapiens 72-87 22967516-1 2012 A mediatorless glucose biosensor was developed by the immobilization of glucose oxidase (GOx) to graphene-functionalized glassy carbon electrode (GCE). Carbon 128-134 hydroxyacid oxidase 1 Homo sapiens 89-92 22967566-0 2012 Analysis of rare earth elements in seawater by inductively coupled plasma mass spectrometry after pre-concentration using TSK -HD-MW-CNTs (highly dispersive multi-walled carbon nanotubes). Carbon 170-176 tsukushi, small leucine rich proteoglycan Homo sapiens 122-125 22979850-0 2012 Highly tunable spin-dependent electron transport through carbon atomic chains connecting two zigzag graphene nanoribbons. Carbon 57-63 spindlin 1 Homo sapiens 15-19 22979850-1 2012 Motivated by recent experiments of successfully carving out stable carbon atomic chains from graphene, we investigate a device structure of a carbon chain connecting two zigzag graphene nanoribbons with highly tunable spin-dependent transport properties. Carbon 67-73 spindlin 1 Homo sapiens 218-222 22979850-1 2012 Motivated by recent experiments of successfully carving out stable carbon atomic chains from graphene, we investigate a device structure of a carbon chain connecting two zigzag graphene nanoribbons with highly tunable spin-dependent transport properties. Carbon 142-148 spindlin 1 Homo sapiens 218-222 22634383-10 2012 Therefore, p65 activation decreases miR-23a expression, which facilitates glutamine consumption allowing leukemic cells to use this alternative source of carbon and favoring their adaptation to the metabolic environment. Carbon 154-160 microRNA 23a Homo sapiens 36-43 22402261-0 2012 Carbonylation and loss-of-function analyses of SBPase reveal its metabolic interface role in oxidative stress, carbon assimilation, and multiple aspects of growth and development in Arabidopsis. Carbon 111-117 sedoheptulose-bisphosphatase Arabidopsis thaliana 47-53 22402261-1 2012 Sedoheptulose-1,7-bisphosphatase (SBPase) is a Calvin cycle enzyme and functions in photosynthetic carbon fixation. Carbon 99-105 sedoheptulose-bisphosphatase Arabidopsis thaliana 0-32 22402261-1 2012 Sedoheptulose-1,7-bisphosphatase (SBPase) is a Calvin cycle enzyme and functions in photosynthetic carbon fixation. Carbon 99-105 sedoheptulose-bisphosphatase Arabidopsis thaliana 34-40 22402261-7 2012 Our findings demonstrate that ROS-induced oxidative damage to SBPase affects growth, development, and chloroplast biogenesis in Arabidopsis through inhibiting carbon assimilation efficiency. Carbon 159-165 sedoheptulose-bisphosphatase Arabidopsis thaliana 62-68 22811435-2 2012 Here, we show that the nucleus-localized transcription factors GATA NITRATE-INDUCIBLE CARBON-METABOLISM-INVOLVED (GNC) and CYTOKININ-RESPONSIVE GATA1 (CGA1) regulate chloroplast development, growth, and division in Arabidopsis (Arabidopsis thaliana). Carbon 86-92 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 63-67 22841105-1 2012 A glucose biosensor was fabricated based on electrostatic self-assembly in combination with in situ photo-cross-linking of glucose oxidase (GOx) and diazoresin-chitosan (DAR-CS) on Prussian blue deposited multi-walled carbon nanotubes (PB-MWNTs) backbone. Carbon 218-224 hydroxyacid oxidase 1 Homo sapiens 123-138 22962799-2 2012 This innovative sensor was constructed with glassy carbon electrode which is represented as (GOx)/CA-CF/(GCE). Carbon 51-57 hydroxyacid oxidase 1 Homo sapiens 93-96 22391101-5 2012 Carbon enriched interlath films with peak carbon levels of 6-10 at.%, which have been identified to be retained austenite by TEM, show a thickness increase with increasing lambda. Carbon 0-6 MFT2 Homo sapiens 125-128 22391101-5 2012 Carbon enriched interlath films with peak carbon levels of 6-10 at.%, which have been identified to be retained austenite by TEM, show a thickness increase with increasing lambda. Carbon 42-48 MFT2 Homo sapiens 125-128 22577963-3 2012 Computational studies have shown that the CHCR reaction is initiated by a hydride transfer to the carbenoid from an allyl site on the substrate, which is then rapidly followed by C-C bond formation between the developing rhodium-bound allyl anion and the allyl cation. Carbon 0-1 muscleblind like splicing regulator 3 Homo sapiens 42-46 22628564-3 2012 Structural and biochemical studies show a direct, specific influence on the c-subunit stoichiometry, revealing c(<11), c(12), c(13), c(14), and c(>14) rings. Carbon 4-5 homeobox C13 Homo sapiens 129-134 22078968-0 2012 Removal of trace organic contaminants by a membrane bioreactor-granular activated carbon (MBR-GAC) system. Carbon 82-88 translocator protein Homo sapiens 90-93 22429844-3 2012 The significant lengthening of C-Br bond in each PBDE congener was observed in the excited state for the first time by theoretical calculation, which is directly involved in the photochemistry reductive debromination of n-BDE to (n-1)-BDE. Carbon 31-32 homeobox D13 Homo sapiens 50-53 22429844-3 2012 The significant lengthening of C-Br bond in each PBDE congener was observed in the excited state for the first time by theoretical calculation, which is directly involved in the photochemistry reductive debromination of n-BDE to (n-1)-BDE. Carbon 31-32 homeobox D13 Homo sapiens 222-225 26286791-0 2012 Carbon-Detected (15)N NMR Spin Relaxation of an Intrinsically Disordered Protein: FCP1 Dynamics Unbound and in Complex with RAP74. Carbon 0-6 FCP1 Homo sapiens 82-86 22583270-0 2012 Communication: electronic band gaps of semiconducting zig-zag carbon nanotubes from many-body perturbation theory calculations. Carbon 62-68 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 58-61 22583270-1 2012 Electronic band gaps for optically allowed transitions are calculated for a series of semiconducting single-walled zig-zag carbon nanotubes of increasing diameter within the many-body perturbation theory GW method. Carbon 123-129 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 119-122 22680745-5 2012 Our results demonstrate a new approach for controlling spin-dependent transport in carbon nanotube double dot devices. Carbon 83-89 spindlin 1 Homo sapiens 55-59 22262063-3 2012 In the renal BBM vesicles, the rSGLT1-independent uptake of [(14)C]-alpha-methyl-D-glucopyranoside was similar in females and males, suggesting functional contribution of another Na(+)-D-glucose cotransporter to glucose reabsorption. Carbon 64-66 solute carrier family 5 member 1 Rattus norvegicus 31-37 22362463-4 2012 An Arduengo type carbene also showed significant BDE values for gem-dimetallation, thus indicating the possible existence of carbon(0) character. Carbon 125-131 homeobox D13 Homo sapiens 49-52 22606099-1 2012 In the title compound, C(30)H(25)ClN(2), the chiral center maintains the S configuration of the stating l-phenyl-alaninol. Carbon 23-24 tripeptidyl peptidase 1 Homo sapiens 33-38 22755133-1 2012 Foam-like carbon (carbon nanofoam, CNF) which belongs to the porous carbon family is formed by pulsed laser ablation of graphite in liquid nitrogen. Carbon 10-16 NPHS1 adhesion molecule, nephrin Homo sapiens 35-38 22330799-6 2012 Using the HXT1 promoter to control ERG9 expression, it was possible to divert the carbon flux from sterol synthesis towards alpha-santalene improving the productivity by 3.4 fold. Carbon 82-88 hexose transporter HXT1 Saccharomyces cerevisiae S288C 10-14 22822413-10 2012 Combined iron+Abeta injection also resulted in more severe DNA damage (both single- and double-strand; p<0.01) and more Fluoro-Jade C staining (p<0.05). Carbon 0-1 amyloid beta precursor protein Rattus norvegicus 14-19 22209981-2 2012 In the present study, we demonstrated the polyI:C-induced gene expression of the damage associated molecular pattern (DAMP) molecules S100A8 and S100A9, while other S100 genes were not affected. Carbon 48-49 S100 calcium binding protein A9 Homo sapiens 145-151 22209981-3 2012 Cycloheximide and Brefeldin A treatment revealed both the expression of S100A8 and S100A9 as secondary response genes and the involvement of polyI:C-induced cytokines herein. Carbon 0-1 S100 calcium binding protein A9 Homo sapiens 83-89 22239772-4 2012 This paper makes a comparative assessment of the different approaches by applying them to potential energy surfaces for different spin states of the oxygen and carbon dimer. Carbon 160-166 spindlin 1 Homo sapiens 130-134 22259551-1 2012 In the title compound, C(13)H(9)Cl(2)NO, the meta-Cl atom in the benzoyl ring is positioned anti to the C=O bond, while the ortho-Cl atom in the aniline ring is positioned syn to the N-H bond. Carbon 23-24 synemin Homo sapiens 172-175 22223342-9 2012 Moreover, the expression of glucose-regulated proteins 94 and 78 (GRP94, 78) decreased according to the number of carbons in the fatty acids. Carbon 114-121 heat shock protein 90 beta family member 1 Homo sapiens 66-71 22020190-1 2012 A chitosan-glutaraldehyde crosslinked uricase was immobilized onto Prussian blue nanoparticles (PBNPs) absorbed onto carboxylated multiwalled carbon nanotube (c-MWCNT) and polyaniline (PANI) layer, electrochemically deposited on the surface of Au electrode. Carbon 142-148 urate oxidase (pseudogene) Homo sapiens 38-45 21994172-3 2012 SnRK1 plays a major role in the regulation of carbon metabolism and energy status, while SnRKs 2 and 3 have been implicated in stress and abscisic acid (ABA)-mediated signalling pathways. Carbon 46-52 snRK1 Triticum aestivum 0-5 23145316-4 2012 By introducing the molecular orbital concept, the dominant fluorescence was found to originate from the electronic transitions among/between the non-oxidized carbon regions and the boundary of oxidized carbon atom regions, where all three kinds of functionalized groups C-O, C = O and O = C-OH were participating. Carbon 158-164 DELYQ11 Homo sapiens 268-284 23145316-4 2012 By introducing the molecular orbital concept, the dominant fluorescence was found to originate from the electronic transitions among/between the non-oxidized carbon regions and the boundary of oxidized carbon atom regions, where all three kinds of functionalized groups C-O, C = O and O = C-OH were participating. Carbon 202-208 DELYQ11 Homo sapiens 268-284 23198093-0 2012 Spin-based optomechanics with carbon nanotubes. Carbon 30-36 spindlin 1 Homo sapiens 0-4 23198093-1 2012 A simple scheme for determination of spin-orbit coupling strength in spinbased optomechanics with carbon nanotubes is introduced, under the control of a strong pump field and a weak signal field. Carbon 98-104 spindlin 1 Homo sapiens 37-41 22792045-1 2012 Under dark anoxia, the unicellular green algae Chlamydomonas reinhardtii may produce hydrogen by means of its hydrogenase enzymes, in particular HYD1, using reductants derived from the degradation of intercellular carbon stores. Carbon 214-220 uncharacterized protein Chlamydomonas reinhardtii 145-149 22029280-1 2011 The reaction of corannulene (C(20)H(10)) with 1,2-C(2)H(4)Hal(2) (Hal = Cl or Br) in the presence of AlCl(3) affords stable nonplanar carbocations C(20)H(10)CH(2)CH(2)Hal(+) (Hal = Cl (1) and Br (2)) with an -CH(2)CH(2)Hal moiety attached to the interior carbon atom of the bowl. Carbon 255-261 histidine ammonia-lyase Homo sapiens 66-69 22029280-1 2011 The reaction of corannulene (C(20)H(10)) with 1,2-C(2)H(4)Hal(2) (Hal = Cl or Br) in the presence of AlCl(3) affords stable nonplanar carbocations C(20)H(10)CH(2)CH(2)Hal(+) (Hal = Cl (1) and Br (2)) with an -CH(2)CH(2)Hal moiety attached to the interior carbon atom of the bowl. Carbon 255-261 histidine ammonia-lyase Homo sapiens 66-69 22199826-1 2011 In the title compound, C(13)H(10)ClNO, the meta-chloro group on the benzoyl ring is positioned syn to the C=O bond. Carbon 23-24 synemin Homo sapiens 95-98 22199826-1 2011 In the title compound, C(13)H(10)ClNO, the meta-chloro group on the benzoyl ring is positioned syn to the C=O bond. Carbon 33-34 synemin Homo sapiens 95-98 21831043-5 2011 PDR18 activation under 2,4-D stress is regulated by the transcription factors Nrg1, controlling carbon source availability and the stress response, and, less significantly, Yap1, involved in oxidative stress and MDR, and Pdr3, a key regulator of the yeast PDR network, consistent with a broad role in stress defence. Carbon 96-102 transcriptional regulator NRG1 Saccharomyces cerevisiae S288C 78-82 21872375-5 2011 The concentrations of all congeners (except BDE-209) were highly correlated with percent organic carbon (%OC) (p>0.05) when the data from Kuwait City was omitted from the analysis. Carbon 97-103 homeobox D13 Homo sapiens 44-47 21862308-2 2011 The detection adopted a reagentless approach, in which the analyte, CA 125, was immobilized on the detecting electrode, which was modified using carbon nanotubes, and the detection signal was obtained by measuring the reduction peak current of the enzyme that was used to label the antibody. Carbon 145-151 mucin 16, cell surface associated Homo sapiens 68-74 21842059-4 2011 A possible pathway for formation of the yne diolate complex [U(C(8)H(8))(C(5)H(5))](2)C(2)O(2) is proposed which involves dimerization of U(C(8)H(8))(C(5)H(5))CO via coordination of the CO O atoms to the opposing U atoms followed by C-C bond formation to form a zig-zag intermediate, stable at low temperatures. Carbon 63-64 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 266-269 21842059-4 2011 A possible pathway for formation of the yne diolate complex [U(C(8)H(8))(C(5)H(5))](2)C(2)O(2) is proposed which involves dimerization of U(C(8)H(8))(C(5)H(5))CO via coordination of the CO O atoms to the opposing U atoms followed by C-C bond formation to form a zig-zag intermediate, stable at low temperatures. Carbon 73-74 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 266-269 22220046-1 2011 In the title compound, C(21)H(21)FN(3)O(2)P, the NH and P(=O) groups of the C(=O)NHP(=O) fragment are in a syn arrangement with respect to each other, as are the two amide H atoms of the two CH(3)-4-C(6)H(4)-NH moieties. Carbon 23-24 synemin Homo sapiens 107-110 22220046-1 2011 In the title compound, C(21)H(21)FN(3)O(2)P, the NH and P(=O) groups of the C(=O)NHP(=O) fragment are in a syn arrangement with respect to each other, as are the two amide H atoms of the two CH(3)-4-C(6)H(4)-NH moieties. Carbon 76-77 synemin Homo sapiens 107-110 22220046-1 2011 In the title compound, C(21)H(21)FN(3)O(2)P, the NH and P(=O) groups of the C(=O)NHP(=O) fragment are in a syn arrangement with respect to each other, as are the two amide H atoms of the two CH(3)-4-C(6)H(4)-NH moieties. Carbon 198-200 synemin Homo sapiens 107-110 21942440-0 2011 Amperometric detection of L-lactate using nitrogen-doped carbon nanotubes modified with lactate oxidase. Carbon 57-63 lysyl oxidase Homo sapiens 88-103 21182991-6 2011 It is suggested that the 5"-phosphodianion group of PLP may play an important role in enzymatic catalysis of carbon deprotonation by providing up to 12 kcal/mol of binding energy that is utilized to stabilize the transition state for the enzymatic reaction. Carbon 109-115 proteolipid protein 1 Homo sapiens 52-55 21185933-2 2011 MTHFR is involved in the one-carbon metabolic pathway which is essential for DNA biosynthesis and the epigenetic process of DNA methylation. Carbon 29-35 methylenetetrahydrofolate reductase Homo sapiens 0-5 22168109-11 2011 The distributions of eight carbon fractions in emissions from the printer and copier showed obviously high OC1 (>20%) and OC2 (approximately 30%), and obviously low EC1-OP (a pyrolyzed carbon fraction) (<10%), when compared with other sources. Carbon 27-33 one cut homeobox 2 Homo sapiens 125-128 21964029-2 2011 A modified analog of alpha-GalCer with a carbon-based glycosidic linkage (alpha-C-GalCer) has generated great interest because of its apparent ability to promote prolonged, Th1-biased immune responses. Carbon 41-47 negative elongation factor complex member C/D Homo sapiens 173-176 21936514-4 2011 An SAR analysis of these activities revealed that potent activity of the analogues against VEGFR2 glycosylation was generally driven by side chains of at least four carbons in composition with branching at the alpha or beta position. Carbon 165-172 kinase insert domain receptor Homo sapiens 91-97 21723185-4 2011 For second-period atoms bonded to C-3, two or more conformers are observed in CCl(4) solution, but when substitution by heavier atoms takes place, only one conformer is observed under the tested conditions, i.e., the gauche form with respect to the C=C-C-X dihedral angle. Carbon 78-79 complement C3 Homo sapiens 34-37 21723185-4 2011 For second-period atoms bonded to C-3, two or more conformers are observed in CCl(4) solution, but when substitution by heavier atoms takes place, only one conformer is observed under the tested conditions, i.e., the gauche form with respect to the C=C-C-X dihedral angle. Carbon 78-79 complement C3 Homo sapiens 34-37 21827200-3 2011 The vibrational IR and Raman spectra of the liquid were interpreted in terms of the most stable syn-gauche conformer (the O C double bond syn with respect to the S-S single bond and the C-S single bond gauche with respect to the S-Cl single bond) in equilibrium with the less stable anti-gauche form, both occurring in two enantiomeric forms. Carbon 124-125 synemin Homo sapiens 96-99 21827200-3 2011 The vibrational IR and Raman spectra of the liquid were interpreted in terms of the most stable syn-gauche conformer (the O C double bond syn with respect to the S-S single bond and the C-S single bond gauche with respect to the S-Cl single bond) in equilibrium with the less stable anti-gauche form, both occurring in two enantiomeric forms. Carbon 124-125 synemin Homo sapiens 138-141 21816617-4 2011 Efficient Pol III transcription, following the shift of cells from a non-fermentable carbon source to glucose, requires phosphorylation of Maf1. Carbon 85-91 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 139-143 21786353-11 2011 The BDE for the second AuCl in [NHC(Me)(AuCl)(2)] is clearly smaller than the values for the second AuCl in doubly aurated carbone complexes. Carbon 123-130 homeobox D13 Homo sapiens 4-7 21652715-0 2011 Npr1 Ser/Thr protein kinase links nitrogen source quality and carbon availability with the yeast nitrate transporter (Ynt1) levels. Carbon 62-68 serine/threonine protein kinase NPR1 Saccharomyces cerevisiae S288C 0-4 21652715-10 2011 We show for the first time that carbon starvation leads to Npr1 phosphorylation, whereas Ynt1 is dephosphorylated and degraded in the vacuole. Carbon 32-38 serine/threonine protein kinase NPR1 Saccharomyces cerevisiae S288C 59-63 21652715-12 2011 We concluded that Npr1 plays a key role in adapting Ynt1 levels to the nitrogen quality and availability of a source of carbon. Carbon 120-126 serine/threonine protein kinase NPR1 Saccharomyces cerevisiae S288C 18-22 22090931-1 2011 In the title compound, C(12)H(15)NO(3) H(2)O, the conformation of the N-H bond in the amide segment is syn to the ortho-methyl group and anti to the meta-methyl group in the benzene ring. Carbon 23-24 synemin Homo sapiens 103-106 21365181-2 2011 Mutation of the transcription factor spt15 was introduced by error-prone PCR, then transformed the recombinant plasmid pYX212-spt15 into Saccharomyces cerevisiae YPH499 which was not able to grow on xylose, and screened on media using lignocellulosic hydrolysates as the sole carbon source. Carbon 276-282 TATA-binding protein Saccharomyces cerevisiae S288C 37-42 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 DNA methyltransferase 1 Homo sapiens 126-131 27293103-0 2016 Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Carbon 139-145 NIN like protein 7 Arabidopsis thaliana 30-34 27293103-8 2016 More importantly, overexpression of NLP7 also enhances photosynthesis rate and carbon assimilation, whereas knockout of NLP7 impaired both nitrogen and carbon assimilation. Carbon 79-85 NIN like protein 7 Arabidopsis thaliana 36-40 27293103-8 2016 More importantly, overexpression of NLP7 also enhances photosynthesis rate and carbon assimilation, whereas knockout of NLP7 impaired both nitrogen and carbon assimilation. Carbon 152-158 NIN like protein 7 Arabidopsis thaliana 120-124 27293103-10 2016 Our results demonstrate that NLP7 significantly improves plant growth under both nitrogen-poor and -rich conditions by coordinately enhancing nitrogen and carbon assimilation and sheds light on crop improvement. Carbon 155-161 NIN like protein 7 Arabidopsis thaliana 29-33 26788794-0 2016 Microstructure characterization of advanced protective Cr/CrN+a-C:H/a-C:H:Cr multilayer coatings on carbon fibre composite (CFC). Carbon 100-106 crooked neck pre-mRNA splicing factor 1 Homo sapiens 58-61 18837492-5 2008 Four energetically accessible reaction routes are revealed, i.e., the decomposition of the nitrite adduct forming C 2Cl 3O + NO and its sequential dissociation to CO + NO + CCl 3, the elimination of ClNO from the nitrite adduct leading to ClNO + Cl 2CCO, the Cl-atom shift of the nitrite adduct followed by the decomposition to CCl 3CO + NO, and the O-atom shift of the nitro adduct followed by C-C bond cleavage forming ClCNO + Cl 2CO. Carbon 117-118 C-C motif chemokine ligand 3 Homo sapiens 173-178 27016566-0 2016 Relating Carbon and Nitrogen Isotope Effects to Reaction Mechanisms during Aerobic or Anaerobic Degradation of RDX (Hexahydro-1,3,5-Trinitro-1,3,5-Triazine) by Pure Bacterial Cultures. Carbon 9-15 radixin Homo sapiens 111-114 27016566-1 2016 UNLABELLED: Kinetic isotopic fractionation of carbon and nitrogen during RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) biodegradation was investigated with pure bacterial cultures under aerobic and anaerobic conditions. Carbon 46-52 radixin Homo sapiens 73-76 18502113-1 2008 A novel multi-components hybrid material, self-assembled quantum dots (CdS) and glutamate dehydrogenase (GDH) onto multiwall carbon nanotubes (CNTs), was designed for amperometric biosensing system. Carbon 125-131 CDP-diacylglycerol synthase 1 Homo sapiens 71-74 27016566-9 2016 IMPORTANCE: This work provides the first systematic evaluation of the isotopic fractionation of carbon and nitrogen in the organic explosive RDX during degradation by different pathways. Carbon 96-102 radixin Homo sapiens 141-144 26823567-12 2016 (11)C-PBR28 was more sensitive than (R)-(11)C-PK11195 in the detection of TSPO overexpression in the HSE rat model, because more brain regions with significantly increased tracer uptake could be found, irrespective of the data analysis method used. Carbon 4-5 translocator protein Rattus norvegicus 74-78 18502113-1 2008 A novel multi-components hybrid material, self-assembled quantum dots (CdS) and glutamate dehydrogenase (GDH) onto multiwall carbon nanotubes (CNTs), was designed for amperometric biosensing system. Carbon 125-131 glutamate dehydrogenase 1 Homo sapiens 80-103 18502113-1 2008 A novel multi-components hybrid material, self-assembled quantum dots (CdS) and glutamate dehydrogenase (GDH) onto multiwall carbon nanotubes (CNTs), was designed for amperometric biosensing system. Carbon 125-131 glutamate dehydrogenase 1 Homo sapiens 105-108 18670728-3 2008 The organic carbon normalized soil sorption coefficient (K(oc)) was calculated to be 94-96 mL/g at 1 h after the application. Carbon 12-18 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 57-62 27002483-0 2016 Hysteresis in Carbon Nanotube Transistors: Measurement and Analysis of Trap Density, Energy Level, and Spatial Distribution. Carbon 14-20 TRAP Homo sapiens 71-75 27002483-6 2016 Through these advances, we are able to quantify the interface trap density for carbon nanotube field-effect transistors (~3 x 10(13) cm(-2) eV(-1) near midgap), and compare this against a range of previously studied dielectric/semiconductor interfaces. Carbon 79-85 TRAP Homo sapiens 62-66 18693307-7 2008 The method is capable of analysing FAME with carbon numbers C4-C24, and is particularly suitable to characterize various types of biodiesel, making it possible to differentiate the origin and type of FAME used in the biodiesel samples. Carbon 45-51 benign adult familial myoclonic epilepsy 1 Homo sapiens 35-39 32263278-5 2016 The GOx immobilized HNT/AgNPs were deposited on the glassy carbon electrode (GCE) and utilized for the bioelectrocatalyzed electrochemical detection of glucose. Carbon 59-65 hydroxyacid oxidase 1 Homo sapiens 4-7 18555688-3 2008 The inhibition degrees of 4 and 5 were weaker than that of thiocarbamoylmethyl analog 3, indicating a remarkable effect of the carbon chain length in thiocarbamoylalkyl groups at the C-4 position on inhibitory activities against hPIV-1 sialidase. Carbon 127-133 complement C4A (Rodgers blood group) Homo sapiens 183-186 26594890-0 2016 Detection of aquaporin-4 antibody using aquaporin-4 extracellular loop-based carbon nanotube biosensor for the diagnosis of neuromyelitis optica. Carbon 77-83 aquaporin 4 Homo sapiens 13-24 26594890-0 2016 Detection of aquaporin-4 antibody using aquaporin-4 extracellular loop-based carbon nanotube biosensor for the diagnosis of neuromyelitis optica. Carbon 77-83 aquaporin 4 Homo sapiens 40-51 26594890-1 2016 Here we propose a carbon nanotube (CNT) field-effect transistor (FET) functionalized with aquaporin-4 (AQP4) extracellular loop peptides for the rapid detection of AQP4 antibody without pretreatment. Carbon 18-24 aquaporin 4 Homo sapiens 90-101 26594890-1 2016 Here we propose a carbon nanotube (CNT) field-effect transistor (FET) functionalized with aquaporin-4 (AQP4) extracellular loop peptides for the rapid detection of AQP4 antibody without pretreatment. Carbon 18-24 aquaporin 4 Homo sapiens 103-107 26594890-1 2016 Here we propose a carbon nanotube (CNT) field-effect transistor (FET) functionalized with aquaporin-4 (AQP4) extracellular loop peptides for the rapid detection of AQP4 antibody without pretreatment. Carbon 18-24 aquaporin 4 Homo sapiens 164-168 18676263-5 2008 The yeast transformants that harbored the INGAP gene with high copies were selected with the auxotroph medium and G418, followed then by PCR verification of the positive transformants, from which the expression of recombinant human INGAP was induced with methanol as the only carbone source. Carbon 276-283 regenerating family member 3 alpha Homo sapiens 42-47 18676263-5 2008 The yeast transformants that harbored the INGAP gene with high copies were selected with the auxotroph medium and G418, followed then by PCR verification of the positive transformants, from which the expression of recombinant human INGAP was induced with methanol as the only carbone source. Carbon 276-283 regenerating family member 3 alpha Homo sapiens 232-237 27043021-2 2016 The reaction proceeds through syn-addition of an aryl group and a silyl group across the carbon-carbon triple bond of an alkyne. Carbon 89-95 synemin Homo sapiens 30-33 18507437-3 2008 A concerted formation of a carbonyl group at the C 2 carbon accounts for the relatively small spin density at C 1 and the enhanced g factor anisotropy of the radical, both well-known properties of this radical from several previous experimental investigations. Carbon 27-33 complement C2 Homo sapiens 49-52 27043021-2 2016 The reaction proceeds through syn-addition of an aryl group and a silyl group across the carbon-carbon triple bond of an alkyne. Carbon 96-102 synemin Homo sapiens 30-33 18681060-1 2008 Reactive thermal degradation of Pt(PPh3)(Cl)(mu2-Cl)2Ru(Cl)(eta3:eta3-C10H16)/Vulcan carbon powder composites gives a nanocomposite powder containing nanocrystals of the expected PtRu alloy phase along with nanocrystals of an unknown substance. Carbon 85-91 protein phosphatase 4 catalytic subunit Homo sapiens 35-39 27078170-6 2016 We found that both elovl1 knockdown embryos contain increased levels of long chain fatty acids from carbon number 14 to 20 as compared to control embryos. Carbon 100-106 ELOVL fatty acid elongase 1a Danio rerio 19-25 18047840-2 2008 The chloroplastic system is composed of a ferredoxin-dependent thioredoxin, with two thioredoxin types (m and f) regulating the activity of enzymes implicated in photosynthetic carbon assimilation. Carbon 177-183 thioredoxin Homo sapiens 63-74 26855221-1 2016 Tyre pyrolysis char (TPC), produced when manufacturing pyrolysis oil from waste tyre, was used as raw material to prepare activated carbons (ACs) by KOH activation. Carbon 132-139 solute carrier family 25 member 19 Homo sapiens 21-24 26855221-1 2016 Tyre pyrolysis char (TPC), produced when manufacturing pyrolysis oil from waste tyre, was used as raw material to prepare activated carbons (ACs) by KOH activation. Carbon 141-144 solute carrier family 25 member 19 Homo sapiens 21-24 26743650-3 2016 The addition of root exudate components increased the n-butanol extractability of BDE-28 and BDE-47 by 20.3-72.5 and 48.6-169.2 %, respectively, which had a positive correlation with the concentrations of dissolved organic carbon (DOC) in the soils (p < 0.01), suggesting that the increase of DOC in the soils by root exudate components was the major factor to enhance the extractability. Carbon 223-229 homeobox D13 Homo sapiens 82-85 26743650-3 2016 The addition of root exudate components increased the n-butanol extractability of BDE-28 and BDE-47 by 20.3-72.5 and 48.6-169.2 %, respectively, which had a positive correlation with the concentrations of dissolved organic carbon (DOC) in the soils (p < 0.01), suggesting that the increase of DOC in the soils by root exudate components was the major factor to enhance the extractability. Carbon 223-229 homeobox D13 Homo sapiens 93-96 18047840-2 2008 The chloroplastic system is composed of a ferredoxin-dependent thioredoxin, with two thioredoxin types (m and f) regulating the activity of enzymes implicated in photosynthetic carbon assimilation. Carbon 177-183 thioredoxin Homo sapiens 85-96 18344204-6 2008 Consistent with this function, yeast PAS kinase is activated by both cell integrity stress and growth in non-fermentative carbon sources. Carbon 122-128 PAS domain containing serine/threonine kinase Mus musculus 37-47 26661926-4 2016 It was shown that increasing the substituent at the C-11 carbon leads to greater differences in the populations of stable states and the corresponding equilibrium energies. Carbon 57-63 RNA polymerase III subunit K Homo sapiens 52-56 18287491-7 2008 These data suggest that, in the bt2-H2328 endosperms, regulatory networks are activated that redirect excess carbon into alternative biosynthetic pathways (amino acid synthesis) or into other tissues (embryo). Carbon 109-115 Glucose-1-phosphate adenylyltransferase small subunit 2, chloroplastic/amyloplastic/cytosolic Zea mays 32-35 26838454-8 2016 The present study demonstrates the suitability of DNA bioinspired water-soluble polycations [(VBT)m(VBA)n](n+) 25 for enzyme immobilization like GOx into laponite hydrogels, and the preparation of highly sensitive and stable bioelectrodes on glassy carbon surface. Carbon 249-255 hydroxyacid oxidase 1 Homo sapiens 145-148 18300021-1 2008 PURPOSE: To investigate the effect of exogenous wild type p53 (Tp53) on murine melanoma B16 cell apoptosis induced by carbon-ion beam (C-beam) irradiation. Carbon 118-124 transformation related protein 53 Mus musculus 58-61 27026438-0 2016 Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation. Carbon 13-19 advanced glycosylation end-product specific receptor Homo sapiens 99-103 18300021-1 2008 PURPOSE: To investigate the effect of exogenous wild type p53 (Tp53) on murine melanoma B16 cell apoptosis induced by carbon-ion beam (C-beam) irradiation. Carbon 118-124 transformation related protein 53 Mus musculus 63-67 18205361-0 2008 Carbon-carbon bond activation of 2,2,6,6-tetramethyl-piperidine-1-oxyl by a Rh(II) metalloradical: a combined experimental and theoretical study. Carbon 0-6 Rh blood group D antigen Homo sapiens 76-82 26918383-0 2016 High-Loading Nano-SnO2 Encapsulated in situ in Three-Dimensional Rigid Porous Carbon for Superior Lithium-Ion Batteries. Carbon 78-84 strawberry notch homolog 2 Homo sapiens 18-21 18205361-0 2008 Carbon-carbon bond activation of 2,2,6,6-tetramethyl-piperidine-1-oxyl by a Rh(II) metalloradical: a combined experimental and theoretical study. Carbon 7-13 Rh blood group D antigen Homo sapiens 76-82 26860184-4 2016 Herein, we developed a CD44 targeted photoacoustic (PA) nanophototherapy agent by conjugating Indocyanine Green (ICG) to hyaluronic acid nanoparticles (HANPs) encapsulated with single-walled carbon nanotubes (SWCNTs), resulting in a theranostic nanocomplex of ICG-HANP/SWCNTs (IHANPT). Carbon 191-197 CD44 antigen Mus musculus 23-27 26875940-1 2016 Carbon-atom extrusion from the ipso-position of a halobenzene ring (C6 H5 X; X=F, Cl, Br, I) and its coupling with a methylene ligand to produce acetylene is not confined to [LaCH2 ](+) ; also, the third-row transition-metal complexes [MCH2 ](+) , M=Hf, Ta, W, Re, and Os, bring about this unusual transformation. Carbon 0-6 acyl-CoA thioesterase 1 Homo sapiens 175-180 18205361-1 2008 Competitive major carbon-carbon bond activation (CCA) and minor carbon-hydrogen bond activation (CHA) channels are identified in the reaction between rhodium(II) meso-tetramesitylporphyrin [Rh(II)(tmp)] (1) and 2,2,6,6-tetramethyl-piperidine-1-oxyl (TEMPO) (2). Carbon 18-24 Rh blood group D antigen Homo sapiens 190-196 21715233-0 2011 Direct electron transfer enhancement of covalently bound tyrosinase to glassy carbon via Woodward"s reagent K. This work describes the reaction mechanism for chemical modification of tyrosinase by Woodward"s Reagent K and its covalent attachment to a glassy carbon electrode. Carbon 78-84 tyrosinase Homo sapiens 57-67 18205361-1 2008 Competitive major carbon-carbon bond activation (CCA) and minor carbon-hydrogen bond activation (CHA) channels are identified in the reaction between rhodium(II) meso-tetramesitylporphyrin [Rh(II)(tmp)] (1) and 2,2,6,6-tetramethyl-piperidine-1-oxyl (TEMPO) (2). Carbon 25-31 Rh blood group D antigen Homo sapiens 190-196 21715233-0 2011 Direct electron transfer enhancement of covalently bound tyrosinase to glassy carbon via Woodward"s reagent K. This work describes the reaction mechanism for chemical modification of tyrosinase by Woodward"s Reagent K and its covalent attachment to a glassy carbon electrode. Carbon 78-84 tyrosinase Homo sapiens 183-193 21715233-0 2011 Direct electron transfer enhancement of covalently bound tyrosinase to glassy carbon via Woodward"s reagent K. This work describes the reaction mechanism for chemical modification of tyrosinase by Woodward"s Reagent K and its covalent attachment to a glassy carbon electrode. Carbon 258-264 tyrosinase Homo sapiens 57-67 18205361-1 2008 Competitive major carbon-carbon bond activation (CCA) and minor carbon-hydrogen bond activation (CHA) channels are identified in the reaction between rhodium(II) meso-tetramesitylporphyrin [Rh(II)(tmp)] (1) and 2,2,6,6-tetramethyl-piperidine-1-oxyl (TEMPO) (2). Carbon 25-31 Rh blood group D antigen Homo sapiens 190-196 21715233-0 2011 Direct electron transfer enhancement of covalently bound tyrosinase to glassy carbon via Woodward"s reagent K. This work describes the reaction mechanism for chemical modification of tyrosinase by Woodward"s Reagent K and its covalent attachment to a glassy carbon electrode. Carbon 258-264 tyrosinase Homo sapiens 183-193 18303189-0 2008 Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. Carbon 87-93 transformation related protein 53, pseudogene Mus musculus 29-32 21726055-1 2011 Twofold sila-substitution (C/Si exchange) of the clinically used RXR-selective retinoid agonist bexarotene leads to disila-bexarotene, which displays pharmacological potency similar to that of the parent carbon compound, as shown in a HeLa-cell-based RXR assay. Carbon 204-210 retinoid X receptor alpha Homo sapiens 65-68 26765150-3 2016 Herein, we develop a one-step carbon nanotube (CNT) assisted synthesis strategy with CNTs" strong adsorbability to mediate the growth of subnanometer-sized MoS(x) on CNTs. Carbon 30-36 MOS proto-oncogene, serine/threonine kinase Homo sapiens 156-159 26784023-3 2016 The free-standing PtCuNi/CNF@CF monolith exhibits high porosities, a well-defined geometry shape, outstanding electron conductivity, and a unique characteristic of localizing platinum-copper-nickel nanoparticles in the tips of carbon nanofibers. Carbon 227-233 NPHS1 adhesion molecule, nephrin Homo sapiens 25-28 20652827-11 2011 Procaterol significantly suppressed poly I:C-induced IP-10 and RANTES in BEAS-2B cells in a dose-dependent manner. Carbon 43-44 C-X-C motif chemokine ligand 10 Homo sapiens 53-58 18196509-7 2008 C-to-N isomerizations proceed by the above-mentioned intramolecular process, with a temperature-dependent contribution from the formation and cleavage of mu2-C,N coordination dimers [{Ru{CH(CN)SO2Ph}(Cp)(PPh3)}2] (15 and 16). Carbon 0-1 protein phosphatase 4 catalytic subunit Homo sapiens 204-208 20652827-11 2011 Procaterol significantly suppressed poly I:C-induced IP-10 and RANTES in BEAS-2B cells in a dose-dependent manner. Carbon 43-44 C-C motif chemokine ligand 5 Homo sapiens 63-69 20652827-13 2011 Dibutyryl-cAMP could confer the similar effects of procaterol on poly I:C-induced IP-10 and RANTES expression. Carbon 72-73 C-X-C motif chemokine ligand 10 Homo sapiens 82-87 20652827-13 2011 Dibutyryl-cAMP could confer the similar effects of procaterol on poly I:C-induced IP-10 and RANTES expression. Carbon 72-73 C-C motif chemokine ligand 5 Homo sapiens 92-98 26608667-3 2016 BAS1 encodes CYP734A1, which inactivates the biologically active BRs via C-26 hydroxylation and is down-regulated by a BR-responsive transcription factor, BZR1. Carbon 13-14 Brassinosteroid signaling positive regulator (BZR1) family protein Arabidopsis thaliana 155-159 26731700-3 2016 Benefiting from the scattering effect of NiFe2O4 nanocrystals and graphitized carbon layers for the condensed stress, the resultant CNF membranes exhibit an enhanced elasticity with a bending radius <12 mum, rapid recovery from the deformations, and a superior softness. Carbon 78-84 NPHS1 adhesion molecule, nephrin Homo sapiens 132-135 18200640-2 2008 We here propose a novel strategy toward the creation of "hierarchical" single-walled carbon nanotube (SWNT) architectures by utilizing SWNT composites with cationic or anionic complementary semi-artificial beta-1,3-glucans as "building blocks". Carbon 85-91 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 206-214 27303693-3 2016 The orthologous Hap2/3/4/5 complex in Saccharomyces cerevisiae exerts a regulatory influence on mitochondrial functions, and Hap4 is subject to glucose repression via the carbon catabolite repressor Mig1. Carbon 171-177 transcription factor HAP4 Saccharomyces cerevisiae S288C 125-129 21665458-1 2011 A facile wet-chemical method was developed to prepare a novel Pt nanoparticle-loaded carbon nanofiber (Pt/CNF) electrode. Carbon 85-91 NPHS1 adhesion molecule, nephrin Homo sapiens 106-109 17919682-3 2008 Here, we show that the organic carbon-normalized sorption coefficient (K(OC)) for diuron is 27-81% higher in 10 A11 horizons than in 10 matching A12 horizons for soils collected from a small (2ha) field. Carbon 31-37 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 71-76 30406218-4 2016 When carbon 5 (C5) of cytosine is substituted with a nitrogen atom (N) in 5-aza-cytosine analogues, the critical beta-elimination reaction cannot proceed, which results in the permanent attachment of 5-aza-cytosine to DNMT. Carbon 5-11 DNA methyltransferase 1 Homo sapiens 218-222 17939658-5 2007 The homolytic cleavage of one C-Br bond in the parent CBr4 molecule yields the CBr3 and Br radicals, which escape from the solvent cage and combine nongeminately to form C2Br6 and Br2, respectively. Carbon 30-31 carbonyl reductase 4 Homo sapiens 54-58 26592858-6 2016 In case of compounds having an aromatic nucleus at the amino terminus, increasing the carbon number between N and the aromatic ring increases the potency as well as selectivity toward hMAO-B. Carbon 86-92 monoamine oxidase B Homo sapiens 184-190 17359949-2 2007 The desired (2)S0 conformation has been obtained by tethering the C-2 and C-5 carbon atoms of the sugar ring with a dimethyloxy bridge and confirmed by NMR and molecular modeling. Carbon 78-84 complement C5 Homo sapiens 74-77 27161009-1 2016 An overview of anticancer active (arene)ruthenium(II) complexes coordinated to period 2 element-based ligand systems, i.e., carbon-, nitrogen-, and oxygen-coordinated ligands, is provided in this mini-review. Carbon 124-130 period circadian regulator 2 Homo sapiens 79-87 26414197-6 2016 For the Ta/Ta2O5 system, a rutile-type TaO2 film is believed to mediate switching, and we show that devices can be switched from a valence change mode to an electrochemical metallization mode by introducing an intermediate layer of amorphous carbon. Carbon 242-248 TAO kinase 2 Homo sapiens 39-43 17685605-11 2007 In the superstructure (P63/mcm, Z=2, a=5.0882(7) A, and c=22.983(5) A) the vacancies on the carbon sites are ordered. Carbon 92-98 tumor protein p63 Homo sapiens 23-35 17524547-3 2007 In both cases, the chimeric carrier, Anc2-Cyc1(His6)p, was able to restore growth on a non-fermentable carbon source of a yeast strain devoid of functional ADP/ATP carrier, demonstrating its transport activity. Carbon 103-109 cytochrome c isoform 1 Saccharomyces cerevisiae S288C 42-46 26563753-2 2015 Here, carbon nanotube field-effect transistors with floating electrodes were hybridized with nanovesicles containing honeybee umami taste receptor, gustatory receptor 10 of Apis mellifera (AmGr10). Carbon 6-12 gustatory receptor 10 Apis mellifera 189-195 17690534-9 2007 The gene showing significantly higher expressions after X-ray irradiation than after carbon-ion beam irradiation was PCNA. Carbon 85-91 proliferating cell nuclear antigen Homo sapiens 117-121 17690534-10 2007 The genes showing significantly lower expressions after X-ray irradiation rather than after carbon-ion beam irradiation were RAD50, BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. Carbon 92-98 mutL homolog 1 Homo sapiens 161-165 17690534-10 2007 The genes showing significantly lower expressions after X-ray irradiation rather than after carbon-ion beam irradiation were RAD50, BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. Carbon 92-98 cyclin B1 Homo sapiens 167-172 17690534-10 2007 The genes showing significantly lower expressions after X-ray irradiation rather than after carbon-ion beam irradiation were RAD50, BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. Carbon 92-98 DNA ligase 4 Homo sapiens 184-188 26539811-1 2015 In this study, a biomemory chip consisting of a myoglobin/carbon nanotube (CNT) heterolayer is fabricated via the protein-adsorption-precipitation-crosslinking (PAPC) technique for electrochemical signal enhancement, long-term stability, and improved memory function. Carbon 58-64 protocadherin 8 Homo sapiens 161-165 17869563-0 2007 A metabolic flux analysis to study the role of sucrose synthase in the regulation of the carbon partitioning in central metabolism in maize root tips. Carbon 89-95 sucrose synthase 1 Zea mays 47-63 26264774-7 2015 As glucose-regulated lysine acetylation was predominant in central metabolic pathways and overlapped with acetyl phosphate-regulated acetylation sites, we deleted the major carbon regulator CRP and observed a dramatic loss of acetylation that could be restored by deleting the enzyme that degrades acetyl phosphate. Carbon 173-179 catabolite gene activator protein Escherichia coli 190-193 26485042-1 2015 DNA methyltransferase 3B (DNMT3B) and methylenetetrahydrofolate reductase (MTHFR) are genes which encode enzymes critical to one-carbon metabolism. Carbon 129-135 methylenetetrahydrofolate reductase Homo sapiens 38-73 26485042-1 2015 DNA methyltransferase 3B (DNMT3B) and methylenetetrahydrofolate reductase (MTHFR) are genes which encode enzymes critical to one-carbon metabolism. Carbon 129-135 methylenetetrahydrofolate reductase Homo sapiens 75-80 17869563-1 2007 In order to understand the role of sucrose synthase (SuSy) in carbon partitioning, metabolic fluxes were analyzed in maize root tips of a double mutant of SuSy genes, sh1 sus1 and the corresponding wild type, W22. Carbon 62-68 sucrose synthase 1 Zea mays 53-57 18069330-0 2007 [Microbial processes of the carbon and sulfur cycles in the Chukchi Sea]. Carbon 28-34 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 68-71 26621579-6 2015 Based on thermoelastic modelling along an expected geotherm, the spin crossover in ferropericlase can contribute to 2% reduction in VP/VS in a pyrolite mineralogical model in mid lower-mantle. Carbon 143-151 spindlin 1 Homo sapiens 65-69 26340696-2 2015 The reaction afforded a variety of dimeric 2-oxindoles with a C-3/C-5" linkage having an all-carbon quaternary center at the pseudobenzylic position in high yields. Carbon 93-99 complement C3 Homo sapiens 62-65 17543313-11 2007 Then isomers differing only in the position of the carbon double bond on the alkyl chain can be separated and their behaviour is summarised as the closer the carbon double bonds to the FAME polar head, the more the retention decreases. Carbon 51-57 benign adult familial myoclonic epilepsy 1 Homo sapiens 185-189 26452011-1 2015 We report the results of ab initio molecular dynamics simulations of Ga13 and Ga17 clusters confined inside carbon nanotubes with different diameters. Carbon 108-114 eukaryotic translation initiation factor 3 subunit M Homo sapiens 78-82 26508036-3 2015 The asymmetric CF2 stretching intensity, calculated to be 126.5 km mol(-1) higher than the symmetric one, is accounted for by an 81.7 km mol(-1) difference owing to the carbon atom displacement and 40.6 km mol(-1) for both fluorine displacements. Carbon 169-175 ATPase H+ transporting accessory protein 1 Homo sapiens 15-18 26508036-6 2015 Contrary to that found for the CF2 vibrations intramolecular charge transfer provoked by the carbon atom displacement almost exclusively explains this difference. Carbon 93-99 ATPase H+ transporting accessory protein 1 Homo sapiens 31-34 17543313-11 2007 Then isomers differing only in the position of the carbon double bond on the alkyl chain can be separated and their behaviour is summarised as the closer the carbon double bonds to the FAME polar head, the more the retention decreases. Carbon 158-164 benign adult familial myoclonic epilepsy 1 Homo sapiens 185-189 17579435-6 2007 The phenanthrene KOC (organic carbon-normalized sorption capacity) of the 12 sorbents ranged from 6960 to 32,900 mL/g, which increased with increasing aliphatic carbons and decreasing aromatic carbons in the tea leaves. Carbon 30-36 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 17-20 28347102-2 2015 The fabricated nanoporous CNF-PtNP hybrids were further utilized to modify glass carbon electrodes and used for the non-enzymatic amperometric biosensor for the highly sensitive detection of hydrogen peroxide (H2O2). Carbon 81-87 NPHS1 adhesion molecule, nephrin Homo sapiens 26-29 17579435-6 2007 The phenanthrene KOC (organic carbon-normalized sorption capacity) of the 12 sorbents ranged from 6960 to 32,900 mL/g, which increased with increasing aliphatic carbons and decreasing aromatic carbons in the tea leaves. Carbon 161-168 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 17-20 17524381-3 2007 On cooling from 95 degrees C and immediate reheating, rac-beta-D-GalDAGs typically show a single, strongly energetic phase transition, corresponding to either a lamellar gel/liquid-crystalline (L(beta)/L(alpha)) phase transition (N< or =15 carbon atoms) or a lamellar gel/inverted hexagonal (L(beta)/H(II)) phase transition (N> or =16). Carbon 243-249 AKT serine/threonine kinase 2 Homo sapiens 54-62 26447487-0 2015 Spin-orbit interaction in bent carbon nanotubes: resonant spin transitions. Carbon 31-37 spindlin 1 Homo sapiens 0-4 26447487-0 2015 Spin-orbit interaction in bent carbon nanotubes: resonant spin transitions. Carbon 31-37 spindlin 1 Homo sapiens 58-62 26447487-1 2015 We develop an effective tight-binding Hamiltonian for spin-orbit (SO) interaction in bent carbon nanotubes (CNT) for the electrons forming the pi bonds between the nearest neighbor atoms. Carbon 90-96 spindlin 1 Homo sapiens 54-58 26525137-3 2015 Iron reduction (FeR) was responsible for 73-81% of total microbial carbon mineralization in September 2012 and 32-61% in February 2014. Carbon 67-73 FER tyrosine kinase Homo sapiens 16-19 17550273-4 2007 We have now made the unexpected discovery that glutathione-S-transferase (GST)-mediated GSH addition to ONE occurs primarily to C-1 of the alpha,beta-unsaturated ketone rather than to C-3 of the alpha,beta-unsaturated aldehyde. Carbon 128-129 glutathione S-transferase kappa 1 Homo sapiens 47-72 17550273-4 2007 We have now made the unexpected discovery that glutathione-S-transferase (GST)-mediated GSH addition to ONE occurs primarily to C-1 of the alpha,beta-unsaturated ketone rather than to C-3 of the alpha,beta-unsaturated aldehyde. Carbon 128-129 glutathione S-transferase kappa 1 Homo sapiens 74-77 17550273-4 2007 We have now made the unexpected discovery that glutathione-S-transferase (GST)-mediated GSH addition to ONE occurs primarily to C-1 of the alpha,beta-unsaturated ketone rather than to C-3 of the alpha,beta-unsaturated aldehyde. Carbon 184-185 glutathione S-transferase kappa 1 Homo sapiens 47-72 17550273-4 2007 We have now made the unexpected discovery that glutathione-S-transferase (GST)-mediated GSH addition to ONE occurs primarily to C-1 of the alpha,beta-unsaturated ketone rather than to C-3 of the alpha,beta-unsaturated aldehyde. Carbon 184-185 glutathione S-transferase kappa 1 Homo sapiens 74-77 17439949-4 2007 Msx treatment increases Snf1-independent Gln3-Myc13 phosphorylation, whereas carbon starvation increases both Snf1-dependent and -independent Gln3-Myc13 phosphorylation. Carbon 77-83 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 142-146 26248647-4 2015 In the liver, they controls the glucokinase/glucose-6-phosphatase switch and bile acid pool composition, directing carbons to glucose or lipid utilisation, thus providing a unifying mechanism for the two abnormalities of the diabetic liver: excessive glucose production and increased lipid synthesis and secretion. Carbon 115-122 glucokinase Homo sapiens 32-43 26726643-3 2015 The synthesized CNF was then converted to activated carbon nanofibers (ACNFs) under flowing CO2. Carbon 52-58 NPHS1 adhesion molecule, nephrin Homo sapiens 16-19 17474740-3 2007 Additional agostic interactions between an ipso-carbon of one of the phenyl groups of the amide ligand and the alkaline earth metal atom lead to unsymmetric coordination of the NPh2 anions with two strongly different M-N-C angles in 3-5. Carbon 48-54 neurexophilin 2 Homo sapiens 177-181 26440479-0 2015 Functionalized Carbon Quantum Dots with Dopamine for Tyrosinase Activity Monitoring and Inhibitor Screening: In Vitro and Intracellular Investigation. Carbon 15-21 tyrosinase Homo sapiens 53-63 26440479-2 2015 In this work, we develop a convenient and real-time assay with high sensitivity for TYR activity/level monitoring and its inhibitor screening based on biocompatible dopamine functionalized carbon quantum dots (Dopa-CQDs). Carbon 189-195 tyrosinase Homo sapiens 84-87 17270373-1 2007 Erythropoietin (EPO) loaded carbon nanotubes (CNTs) with surfactant as an absorption enhancer were prepared for the oral delivery of EPO using two types of CNTs, long and short fiber length CNTs, and the effect of CNT fiber length on the absorption efficiency of EPO was studied. Carbon 28-34 erythropoietin Rattus norvegicus 16-19 26497596-3 2015 We show that AtMYB12 not only increases the demand of flavonoid biosynthesis but also increases the supply of carbon from primary metabolism, energy and reducing power, which may fuel the shikimate and phenylalanine biosynthetic pathways to supply more aromatic amino acids for secondary metabolism. Carbon 110-116 myb domain protein 12 Arabidopsis thaliana 13-20 17221238-4 2007 This means that the As-C bond to the longer carbon chain was cleaved during the hydride-generation process. Carbon 44-50 steroid sulfatase Homo sapiens 20-24 26713104-3 2015 We report here a short, three-step synthesis of Boc-2",6"-dimethyl-l-tyrosine (3a) utilizing a microwave-assisted Negishi coupling for the key carbon-carbon bond forming step, and employ this chemistry for the expedient synthesis of other unnatural tyrosine derivatives. Carbon 143-149 BOC cell adhesion associated, oncogene regulated Homo sapiens 48-51 26713104-3 2015 We report here a short, three-step synthesis of Boc-2",6"-dimethyl-l-tyrosine (3a) utilizing a microwave-assisted Negishi coupling for the key carbon-carbon bond forming step, and employ this chemistry for the expedient synthesis of other unnatural tyrosine derivatives. Carbon 150-156 BOC cell adhesion associated, oncogene regulated Homo sapiens 48-51 21837179-1 2011 In the title compound, C(24)H(25)NO, the phenyl and diphenyl-methanol substituents are syn to each other. Carbon 23-25 synemin Homo sapiens 87-90 17482557-1 2007 Folate-activated one-carbon units are derived from serine through the activity of the pyridoxal-phosphate (PLP)-dependent isozymes of serine hydroxymethyltransferase (SHMT). Carbon 21-27 serine hydroxymethyltransferase 1 Homo sapiens 134-165 21950073-4 2011 It this process, C-3 and C-4 atoms, which determine the "heavy" isotope composition of carbon of CO2 of the light-induced dark respiration component are split off from the hexose link of sucrose. Carbon 87-93 complement C3 Homo sapiens 17-20 26103880-0 2015 miR-370 and miR-373 regulate the pathogenesis of osteoarthritis by modulating one-carbon metabolism via SHMT-2 and MECP-2, respectively. Carbon 82-88 serine hydroxymethyltransferase 2 Homo sapiens 104-110 26215343-0 2015 Glucose biosensor based on glucose oxidase immobilized at gold nanoparticles decorated graphene-carbon nanotubes. Carbon 96-102 hydroxyacid oxidase 1 Homo sapiens 27-42 17482557-1 2007 Folate-activated one-carbon units are derived from serine through the activity of the pyridoxal-phosphate (PLP)-dependent isozymes of serine hydroxymethyltransferase (SHMT). Carbon 21-27 serine hydroxymethyltransferase 1 Homo sapiens 167-171 21966284-1 2011 In order to investigate the SAR of Ezetimibe analogs for cholesterol absorption inhibitions, amide group and electron-deficient pyridine ring were introduced to the C-(3) carbon chain of Ezetimibe. Carbon 171-177 sarcosine dehydrogenase Homo sapiens 28-31 17396222-3 2007 In the various organisms in which it does occur, DAAO fulfills distinct physiological functions: from a catabolic role in yeast cells, which allows them to grow on D-amino acids as carbon and energy sources, to a regulatory role in the human brain, where it controls the levels of the neuromodulator D-serine. Carbon 181-187 D-amino acid oxidase Homo sapiens 49-53 21682510-2 2011 Plots of the C-Hal bond-length change versus the corresponding vibrational frequency shift of the C-Hal stretch all give straight lines. Carbon 13-14 histidine ammonia-lyase Homo sapiens 15-18 26722495-5 2015 The genotype and allele frequencies of SPTY2D1 rs17579600 SNP were different between the Han and Mulao populations (TT, 74.3% vs. 55.7%; TC, 17.6% vs. 31.2%, CC, 8.1% vs. 13.1%, P = 0.028; T, 83.1% vs. 71.3%; C, 16.9% vs. 28.7%, P = 0.044), and between males and females in the both ethnic groups. Carbon 138-139 SPT2 chromatin protein domain containing 1 Homo sapiens 39-46 26246447-7 2015 Moreover, GOX3 rescues the lethal growth phenotype of a yeast strain lacking CYB2, which cannot grow on l-lactate as a sole carbon source. Carbon 124-130 Aldolase-type TIM barrel family protein Arabidopsis thaliana 10-14 21682510-2 2011 Plots of the C-Hal bond-length change versus the corresponding vibrational frequency shift of the C-Hal stretch all give straight lines. Carbon 13-14 histidine ammonia-lyase Homo sapiens 100-103 21682510-2 2011 Plots of the C-Hal bond-length change versus the corresponding vibrational frequency shift of the C-Hal stretch all give straight lines. Carbon 98-99 histidine ammonia-lyase Homo sapiens 15-18 17178245-1 2007 The enzyme UDP-galactose-4-epimerase (GAL10) catalyzes a key step in galactose metabolism converting UDP-galactose to UDP-glucose which then can get metabolized through glycolysis and TCA cycle thus allowing the cell to use galactose as a carbon and energy source. Carbon 239-245 bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase Saccharomyces cerevisiae S288C 38-43 21754797-1 2011 In the crystal of the title compound, C(16)H(12)Cl(2)N(2)O(2), the two C=O groups are anti to each other, while one of them is syn and the other is anti to their adjacent C-H bonds. Carbon 38-39 synemin Homo sapiens 127-130 21754829-1 2011 In the title compound, C(22)H(21)BrO, other than the Br atom, the non-H atoms are approximately co-planar [maxium deviation = 0.178 (2) A] and the alk-oxy chain shows an all-anti conformation. Carbon 23-24 ALK receptor tyrosine kinase Homo sapiens 147-150 21320165-10 2011 Albuterol and fenoterol suppressed poly I:C-induced RANTES and IP-10 expression of BEAS-2B cells. Carbon 42-43 C-C motif chemokine ligand 5 Homo sapiens 52-58 26272099-7 2015 In this work, we used hybrid steered molecular dynamics to accurately compute the binding free energies between BLG and the five saturated FAs of 8 to 16 carbon atoms. Carbon 154-160 beta-lactoglobulin Bos taurus 112-115 21320165-10 2011 Albuterol and fenoterol suppressed poly I:C-induced RANTES and IP-10 expression of BEAS-2B cells. Carbon 42-43 C-X-C motif chemokine ligand 10 Homo sapiens 63-68 17696012-1 2007 Aminylferrocene(FcAI)-Nanogold(NG) modified glassy carbon electrode (FcAI/NG/GCE) was prepared by the Au-N bond between Au and FcAI. Carbon 51-57 aminomethyltransferase Homo sapiens 69-80 21478008-1 2011 A novel electrochemical glucose biosensor was developed based on in situ covalent immobilization of glucose oxidase (GOx) by one-pot chitosan (CS)-incorporated sol-gel process in the presence of Prussian blue deposited multi-walled carbon nanotubes hybrids (PB/MWNTs) using 3-isocyanatopropyltriethoxysilane (ICPTES) as both a sol-gel precursor and a covalent coupling agent for GOx and CS. Carbon 232-238 hydroxyacid oxidase 1 Homo sapiens 100-115 21478008-1 2011 A novel electrochemical glucose biosensor was developed based on in situ covalent immobilization of glucose oxidase (GOx) by one-pot chitosan (CS)-incorporated sol-gel process in the presence of Prussian blue deposited multi-walled carbon nanotubes hybrids (PB/MWNTs) using 3-isocyanatopropyltriethoxysilane (ICPTES) as both a sol-gel precursor and a covalent coupling agent for GOx and CS. Carbon 232-238 hydroxyacid oxidase 1 Homo sapiens 117-120 26254295-10 2015 In summary, we designed a novel drug delivery system based on carbon nanotubes loaded with Pt-prodrugs and functionalized with anti-CD133 antibodies. Carbon 62-68 prominin 1 Mus musculus 132-137 26270239-1 2015 Although recent experimental studies have demonstrated that H2 and D2 molecules wet the inner surface of supergrowth carbon nanotubes at low temperatures, characterization of the structural and dynamical properties in this regime is challenging. Carbon 117-123 relaxin 2 Homo sapiens 60-69 17445548-1 2007 The 10-formyl moiety of 10-formyltetrahydrofolate is the source of carbons at the positions 8 (C(8)) and 2 (C(2)) of the purine ring, originating from formate and a few amino acids. Carbon 67-74 complement C2 Homo sapiens 108-112 26260341-0 2015 Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA viruses. Carbon 0-6 tyrosinase Homo sapiens 27-37 26260341-1 2015 Hydroxytyrosol and dihydrocaffeoyl catechols with lipophilic properties have been synthesized in high yield using tyrosinase immobilized on multi-walled carbon nanotubes by the Layer-by-Layer technique. Carbon 153-159 tyrosinase Homo sapiens 114-124 21445391-1 2011 Ferrocene-encapsulated single-walled carbon nanotubes (Fc@SWNTs) are developed as carriers for attaching SnO(2). Carbon 37-43 strawberry notch homolog 2 Homo sapiens 105-108 21445391-2 2011 When Fc@SWNTs coated with SnO(2) nanoparticles were used as anode material in lithium ion batteries, the reversible capacity remained over 900 mA h g(-1) after 40 cycles, much higher than other carbon nanomaterials. Carbon 194-200 strawberry notch homolog 2 Homo sapiens 26-29 17407360-0 2007 Regioselective alkenylation of aromatic ketones with alkenylboronates using a RuH2(CO)(PPh3)3 catalyst via carbon-hydrogen bond cleavage. Carbon 107-113 protein phosphatase 4 catalytic subunit Homo sapiens 87-91 21094255-4 2011 Evidence is presented to show that in the case of CYP17 the attack of Fe(III)-O-O(-) on the target carbon is promoted by cytochrome b(5), which acts as a conformational regulator of CYP17. Carbon 99-105 mitochondrially encoded cytochrome b Homo sapiens 121-133 26234706-0 2015 The Arabidopsis vacuolar sugar transporter SWEET2 limits carbon sequestration from roots and restricts Pythium infection. Carbon 57-63 Nodulin MtN3 family protein Arabidopsis thaliana 43-49 26234706-6 2015 Loss-of-function sweet2 mutants showed reduced tolerance to excess glucose, lower glucose accumulation in leaves, and 15-25% higher glucose-derived carbon efflux from roots, suggesting that SWEET2 has a role in preventing the loss of sugar from root tissue. Carbon 148-154 Nodulin MtN3 family protein Arabidopsis thaliana 17-23 26234706-6 2015 Loss-of-function sweet2 mutants showed reduced tolerance to excess glucose, lower glucose accumulation in leaves, and 15-25% higher glucose-derived carbon efflux from roots, suggesting that SWEET2 has a role in preventing the loss of sugar from root tissue. Carbon 148-154 Nodulin MtN3 family protein Arabidopsis thaliana 190-196 17321747-2 2007 The allylic alcohol portion comprising the C-3, C-4, and C-5 carbons is essential for this function. Carbon 61-68 complement C5 Homo sapiens 57-60 26237666-0 2015 One-Pot Synthesis of Three-Dimensional Graphene/Carbon Nanotube/SnO2 Hybrid Architectures with Enhanced Lithium Storage Properties. Carbon 48-54 strawberry notch homolog 2 Homo sapiens 64-67 21481254-7 2011 Furthermore, a higher flux at the entrance of the TCA was noticed due to arcA gene deletion, resulting in a reduced production of acetate and less carbon loss. Carbon 147-153 DNA-binding transcriptional dual regulator ArcA Escherichia coli str. K-12 substr. MG1655 73-77 21754195-1 2011 In the title compound, C(9)H(20)N(2)S, the n-butyl groups are in syn and anti positions in relation to the C=S bond. Carbon 23-24 synemin Homo sapiens 65-68 17375957-4 2007 Because the preferred conformation of the diol in the formed complex is known, we are able to determine the absolute configuration of the carbon atoms in the diol subunit even in flexible tert/tert vic-diols. Carbon 138-144 telomerase reverse transcriptase Homo sapiens 188-192 21754195-1 2011 In the title compound, C(9)H(20)N(2)S, the n-butyl groups are in syn and anti positions in relation to the C=S bond. Carbon 107-108 synemin Homo sapiens 65-68 26443588-2 2007 All the folic acid derivatives that serve as recipients and donors of one-carbon units are derivatives of tetrahydrofolate, which is formed from dihydrofolate by an NADPH-dependent reduction catalyzed by dihydrofolate reductase (FolA). Carbon 74-80 dihydrofolate reductase type I Escherichia coli 229-233 21346092-2 2011 Serine hydroxymethyltransferase (SHMT1) partitions folate-derived one-carbon units to thymidylate biosynthesis at the expense of cellular methylation, and therefore SHMT1-deficient mice are a model to investigate the metabolic origin of folate-associated pathologies. Carbon 70-76 serine hydroxymethyltransferase 1 (soluble) Mus musculus 33-38 26343443-1 2015 We present a novel electrochemical glucose sensor employing an interdigitated array (IDA) of 1:1 aspect ratio carbon nanoelectrodes for the electrochemical-enzymatic redox cycling of redox species (ferricyanide/ferrocyanide) between glucose oxidase (GOx) and the two comb-shaped nanoelectrodes of the IDA. Carbon 110-116 hydroxyacid oxidase 1 Homo sapiens 233-248 26343443-1 2015 We present a novel electrochemical glucose sensor employing an interdigitated array (IDA) of 1:1 aspect ratio carbon nanoelectrodes for the electrochemical-enzymatic redox cycling of redox species (ferricyanide/ferrocyanide) between glucose oxidase (GOx) and the two comb-shaped nanoelectrodes of the IDA. Carbon 110-116 hydroxyacid oxidase 1 Homo sapiens 250-253 26138361-2 2015 This process allows syn substituents to be established stereospecifically on the 2-carbon bridge connecting the ketone carbonyl carbons, and the formation of one carbon-carbon and two carbon-oxygen bonds. Carbon 119-125 synemin Homo sapiens 20-23 26138361-2 2015 This process allows syn substituents to be established stereospecifically on the 2-carbon bridge connecting the ketone carbonyl carbons, and the formation of one carbon-carbon and two carbon-oxygen bonds. Carbon 119-125 synemin Homo sapiens 20-23 21310169-1 2011 The production of carbon nanofibers and nanotubes (CNF/CNT) and their composite products is increasing globally. Carbon 18-24 NPHS1 adhesion molecule, nephrin Homo sapiens 51-54 17445553-9 2007 Sparse sample algorithms used to estimate 12-hour AUC including C(0), C(1), C(2), C(3), C(4), and/or C(6) showed a good correlation with the calculated AUC(0-6) (r(2) = .81-.96). Carbon 52-53 heterogeneous nuclear ribonucleoprotein C Homo sapiens 70-74 21317495-0 2011 The effect of amine protonation on the electrical properties of spin-assembled single-walled carbon nanotube networks. Carbon 93-99 spindlin 1 Homo sapiens 64-68 26138361-2 2015 This process allows syn substituents to be established stereospecifically on the 2-carbon bridge connecting the ketone carbonyl carbons, and the formation of one carbon-carbon and two carbon-oxygen bonds. Carbon 119-125 synemin Homo sapiens 20-23 17445553-9 2007 Sparse sample algorithms used to estimate 12-hour AUC including C(0), C(1), C(2), C(3), C(4), and/or C(6) showed a good correlation with the calculated AUC(0-6) (r(2) = .81-.96). Carbon 52-53 complement C2 Homo sapiens 76-80 17445553-9 2007 Sparse sample algorithms used to estimate 12-hour AUC including C(0), C(1), C(2), C(3), C(4), and/or C(6) showed a good correlation with the calculated AUC(0-6) (r(2) = .81-.96). Carbon 52-53 complement C4A (Rodgers blood group) Homo sapiens 88-92 17347705-4 2007 The internal rotation barrier heights of the ester methyl group and the alpha-carbon methyl group were calculated to be 5.4 and 14.5 kJ mol(-1) at the MP2/aug-cc-pVDZ level of theory for the most stable conformer. Carbon 78-84 tryptase pseudogene 1 Homo sapiens 151-154 26049001-2 2015 In this study, overall ATPase activity of glycerol alone and mixed carbon sources (glucose and glycerol) fermented E. coli wild type and different Hyd mutants and its inhibition by N,N"-dicyclohexylcarbodiimide (DCCD) were first investigated. Carbon 67-73 ATPase Escherichia coli 23-29 26049001-5 2015 Moreover, total ATPase activity of mixed carbon fermented wild type cells was maximal at pH 7.5 and lowered at pH 5.5. Carbon 41-47 ATPase Escherichia coli 16-22 21406397-3 2011 Cytoplasmic serine hydroxymethyltransferase (SHMT1) regulates the partitioning of folate-activated one-carbons between thymidylate and S-adenosylmethionine biosynthesis. Carbon 103-110 serine hydroxymethyltransferase 1 (soluble) Mus musculus 45-50 19071481-1 2007 A sensitive optical method based on quantum dot (QD) technology is demonstrated for the detection of an important cancer marker, total prostate-specific antigen (TPSA) on a disposable carbon substrate surface. Carbon 184-190 kallikrein related peptidase 3 Homo sapiens 135-167 21302350-1 2011 Methylenetetrahydrofolate reductase (MTHFR) is involved in the one-carbon cycle, which is of importance for nucleotide synthesis and methylation of DNA, membranes, proteins and lipids. Carbon 67-73 methylenetetrahydrofolate reductase Homo sapiens 0-35 21302350-1 2011 Methylenetetrahydrofolate reductase (MTHFR) is involved in the one-carbon cycle, which is of importance for nucleotide synthesis and methylation of DNA, membranes, proteins and lipids. Carbon 67-73 methylenetetrahydrofolate reductase Homo sapiens 37-42 26049001-9 2015 The impact of Hyd-1 and Hyd-2 on the FOF1-ATPase is more obvious during mixed carbon fermentation at slightly acidic pH. Carbon 78-84 ATPase Escherichia coli 42-48 25805039-0 2015 Association of folate and other one-carbon related nutrients with hypermethylation status and expression of RARB, BRCA1, and RASSF1A genes in breast cancer patients. Carbon 36-42 BRCA1 DNA repair associated Homo sapiens 114-119 25805039-0 2015 Association of folate and other one-carbon related nutrients with hypermethylation status and expression of RARB, BRCA1, and RASSF1A genes in breast cancer patients. Carbon 36-42 Ras association domain family member 1 Homo sapiens 125-132 19071481-2 2007 Immuno-recognition was carried out on a carbon substrate using a sandwich assay approach, where the primary antibody (Ab)-protein A complex covalently bound to the substrate surface, was allowed to capture TPSA. Carbon 40-46 kallikrein related peptidase 3 Homo sapiens 206-210 16765044-5 2007 The polluted water contaminated with an individual dye or mixtures of dyes treated with soluble and immobilized potato polyphenol oxidase resulted in the remarkable loss in total organic carbon. Carbon 187-193 catechol oxidase B, chloroplastic Solanum tuberosum 119-137 24891183-4 2015 WES of two affected individuals (a mother and son) and the mother"s unaffected parents identified a mutation in the C-propeptide cleavage site of COL1A1. Carbon 116-117 collagen type I alpha 1 chain Homo sapiens 146-152 21257817-6 2011 Elevated transcript levels of SAK1, but not HAP4, resulted in increased biomass yields in batch cultures grown on glucose (aerobic and excess glucose) as well as on nonfermentable carbon sources. Carbon 180-186 serine/threonine protein kinase SAK1 Saccharomyces cerevisiae S288C 30-34 21358759-4 2011 While expression of glcB in PAO1, an acute isolate of P. aeruginosa, responds to some carbon sources that use the glyoxylate pathway, expression of glcB in FRD1, a CF isolate, is constitutively upregulated. Carbon 86-92 malate synthase G Pseudomonas aeruginosa PAO1 20-24 17134691-5 2007 Here we report that ErbB signals control both C&E and head mesoderm migration. Carbon 46-47 epidermal growth factor receptor S homeolog Xenopus laevis 20-24 21522476-1 2011 In the title compound, C(22)H(28)F(2)NO(2) (+) CHO(2) (-), there are three independent pyrrolidinium formate salt mol-ecules. Carbon 23-24 EBP cholestenol delta-isomerase Homo sapiens 47-53 26141892-5 2015 O2-TPO (temperature programmed oxidation) profiles suggest that the airborne BC oxidation could be classified as the oxidation of amorphous carbon, which falls in the range of 406-490 C with peaks at 418, 423 and 475 C, respectively. Carbon 140-146 thyroid peroxidase Homo sapiens 3-6 26024212-0 2015 Novel ferrocene-anchored ZnO nanoparticle/carbon nanotube assembly for glucose oxidase wiring: application to a glucose/air fuel cell. Carbon 42-48 hydroxyacid oxidase 1 Homo sapiens 71-86 17325628-7 2007 NIH-3T3 fibroblast adhesion to fibronectin was enhanced by 4.7-fold with a 30 minute PureWay-CTM treatment while Ester-C increased fibroblast adhesion by only 1.5 fold. Carbon 93-94 fibronectin 1 Rattus norvegicus 31-42 27308197-3 2015 The methodology presented can be expanded to the synthesis of various higher sugars by means of syn-selective carbon-carbon-bond-forming aldol reactions promoted by primary-based organocatalysts. Carbon 110-116 synemin Homo sapiens 49-52 27308197-3 2015 The methodology presented can be expanded to the synthesis of various higher sugars by means of syn-selective carbon-carbon-bond-forming aldol reactions promoted by primary-based organocatalysts. Carbon 117-123 synemin Homo sapiens 49-52 25897818-0 2015 Inhibiting the VIM-2 Metallo-beta-Lactamase by Graphene Oxide and Carbon Nanotubes. Carbon 66-72 vimentin 2, pseudogene Homo sapiens 15-20 21266088-8 2011 Indeed, a 2-APB analogue where the boron-oxygen core is replaced by a carbon-phosphorus core is devoid of potentiating capacity (while retaining inhibition capacity), highlighting the key role of the boron-oxygen core present in borinate esters for the potentiation function. Carbon 70-76 arginyl aminopeptidase Homo sapiens 12-15 21147339-0 2011 Toluidine blue adsorbed on alcohol dehydrogenase modified glassy carbon electrode for voltammetric determination of ethanol. Carbon 65-71 aldo-keto reductase family 1 member A1 Homo sapiens 27-48 21147347-1 2011 The immobilization of tyrosinase onto glutaraldehyde activated streptavidine magnetic particles and subsequent retention onto a magnetized carbon paste electrode for the amperometric assay of tyrosinase inhibitors is described. Carbon 139-145 tyrosinase Homo sapiens 22-32 21147347-1 2011 The immobilization of tyrosinase onto glutaraldehyde activated streptavidine magnetic particles and subsequent retention onto a magnetized carbon paste electrode for the amperometric assay of tyrosinase inhibitors is described. Carbon 139-145 tyrosinase Homo sapiens 192-202 17266226-4 2007 The trans-COOR conformer with hydrogen bonding between the OH group and the C=O group attached to the same chiral carbon is dominant for dialkyl tartrates both in vacuum and in CCl4. Carbon 10-11 C-C motif chemokine ligand 4 Homo sapiens 177-181 21628884-8 2011 These results suggest (i) that PFCAs with a chain length of 6-9 carbons change the fatty acid profile of hepatic lipids by increasing contents and proportions of 16 : 1, 18 : 1 and 20 : 3, (ii) that these alterations in fatty acid profile are caused by up-regulation of SCD, de novo fatty acid synthesis, chain elongase and Delta6 desaturase and (iii) that the mechanism underlying SCD induction is, in part, mediated through peroxisome proliferator-activated receptor alpha. Carbon 64-71 stearoyl-Coenzyme A desaturase 1 Mus musculus 270-273 21628884-8 2011 These results suggest (i) that PFCAs with a chain length of 6-9 carbons change the fatty acid profile of hepatic lipids by increasing contents and proportions of 16 : 1, 18 : 1 and 20 : 3, (ii) that these alterations in fatty acid profile are caused by up-regulation of SCD, de novo fatty acid synthesis, chain elongase and Delta6 desaturase and (iii) that the mechanism underlying SCD induction is, in part, mediated through peroxisome proliferator-activated receptor alpha. Carbon 64-71 fatty acid desaturase 2 Mus musculus 330-341 21628884-8 2011 These results suggest (i) that PFCAs with a chain length of 6-9 carbons change the fatty acid profile of hepatic lipids by increasing contents and proportions of 16 : 1, 18 : 1 and 20 : 3, (ii) that these alterations in fatty acid profile are caused by up-regulation of SCD, de novo fatty acid synthesis, chain elongase and Delta6 desaturase and (iii) that the mechanism underlying SCD induction is, in part, mediated through peroxisome proliferator-activated receptor alpha. Carbon 64-71 stearoyl-Coenzyme A desaturase 1 Mus musculus 382-385 17266226-4 2007 The trans-COOR conformer with hydrogen bonding between the OH group and the C=O group attached to the same chiral carbon is dominant for dialkyl tartrates both in vacuum and in CCl4. Carbon 114-120 C-C motif chemokine ligand 4 Homo sapiens 177-181 25879801-3 2015 A novel electron-deficient olefin ligand, Fro-DO, proved crucial for achieving high rates and chemoselectivity for C-C bond formation over beta-H elimination. Carbon 115-116 dishevelled binding antagonist of beta catenin 1 Homo sapiens 42-48 25879801-3 2015 A novel electron-deficient olefin ligand, Fro-DO, proved crucial for achieving high rates and chemoselectivity for C-C bond formation over beta-H elimination. Carbon 117-118 dishevelled binding antagonist of beta catenin 1 Homo sapiens 42-48 22072883-3 2011 In the absence of electrical stimulation, myoblasts also differentiated on the electrospun polyurethane carbon nanotube scaffolds, as evidenced by expression of Myf-5 and myosin heavy chains. Carbon 104-110 myogenic factor 5 Homo sapiens 161-166 17676574-1 2007 Water-soluble carbon-nanohorn-tetrathiafulvalene (CNH-TTF) nanoensembles were prepared by utilizing positively charged pyrene as an assembly medium and characterized by spectroscopy and electron microscopy. Carbon 14-20 ras homolog family member H Homo sapiens 54-57 26415451-3 2015 The carbon chain-length of gasoline is within the scope of C7 to C11. Carbon 4-10 RNA polymerase III subunit K Homo sapiens 65-68 21125681-3 2011 FASN is a key metabolic enzyme that catalyses the synthesis of palmitate from the condensation of malonyl-CoA and acetyl-CoA de novo and plays a central role in energy homeostasis, by converting excess carbon intake into fatty acids for storage. Carbon 202-208 fatty acid synthase Homo sapiens 0-4 18067453-5 2007 Previously, we demonstrated that cSHMT-derived folate activated one-carbon units are preferentially incorporated into thymidylate, and we provided evidence that this was achieved through modification with small ubiquitin-like modifier (SUMO) enabling SUMO-dependent nuclear localization of cSHMT during S-phase. Carbon 68-74 serine hydroxymethyltransferase 1 Homo sapiens 33-38 21343678-8 2011 Expression of ICAM-1 was increased by X-ray and carbon-ion beam irradiation and decreased significantly with SB431542 after both irradiations. Carbon 48-54 intercellular adhesion molecule 1 Homo sapiens 14-20 26415451-4 2015 The carbon chain length of kerosene is within the scope of C12 to C15. Carbon 4-10 placenta associated 8 Homo sapiens 66-69 26415451-5 2015 And the carbon chain length of diesel is within the scope of C15 to C18. Carbon 8-14 placenta associated 8 Homo sapiens 61-64 25995901-3 2015 The oxirane O atom and the bridging ester O atom are in an approximate syn conformation [O-C-C-O = -25.4 (3) ] In the crystal, inversion dimers linked by pair of C-H O hydrogen bonds generate R 2 (2)(8) loops, where the C-H donor group forms part of the oxirane ring. Carbon 93-94 synemin Homo sapiens 71-74 18067453-5 2007 Previously, we demonstrated that cSHMT-derived folate activated one-carbon units are preferentially incorporated into thymidylate, and we provided evidence that this was achieved through modification with small ubiquitin-like modifier (SUMO) enabling SUMO-dependent nuclear localization of cSHMT during S-phase. Carbon 68-74 serine hydroxymethyltransferase 1 Homo sapiens 290-295 26113881-2 2015 Alcohol dehydrogenase was immobilized, embedded in an alginate-silicate hybrid gel, on a carbon felt (CF) electrode. Carbon 89-95 aldo-keto reductase family 1 member A1 Homo sapiens 0-21 21343678-9 2011 The expression of ICAM-1 by 2 Gy of carbon-ion beam irradiation was 6.7 fold higher than that of non-irradiated cells, while 5 Gy of X-ray irradiation increased the expression of ICAM-1 by 2.5 fold. Carbon 36-42 intercellular adhesion molecule 1 Homo sapiens 18-24 17227418-8 2007 We thus hypothesize that terminal carbon mineralization in surface sediments of the Black Sea is largely due to the sulfate reduction activity of previously hidden SRM. Carbon 34-40 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 90-93 21343678-10 2011 According to ICAM-1 expression, the effect of carbon-ion beam irradiation was about 2.2, 4.4 and 5.0 times greater than that of the same doses of X-ray irradiation (1, 2 and 5 Gy, respectively). Carbon 46-52 intercellular adhesion molecule 1 Homo sapiens 13-19 21343678-12 2011 Carbon-ion beam induced significantly higher ICAM-1 expression than X-ray. Carbon 0-6 intercellular adhesion molecule 1 Homo sapiens 45-51 20932985-0 2011 Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-alpha via distinct NF-kappaB pathways in human nasal epithelial cells. Carbon 7-8 F11 receptor Homo sapiens 32-37 20932985-6 2011 Both the reduction of JAM-A expression and the induction of secretion of IL-8 and TNF-alpha after treatment with poly(I:C) were modulated by distinct signal transduction pathways via EGFR, PI3K, and p38 MAPK and finally regulated by a TLR3-mediated NF-kappaB pathway. Carbon 120-121 F11 receptor Homo sapiens 22-27 20858221-11 2010 These results implicate Mth1p as a novel regulator of Nhx1p that responds to specific extracellular carbon sources. Carbon 100-106 bifunctional K:H/Na:H antiporter NHX1 Saccharomyces cerevisiae S288C 54-59 20685216-5 2010 Hydroxylations at C-6, C-10, C-11, C-15 positions and alpha,beta-unsaturation at C-1/C-2, C-4/C-5 showed potent inhibitory activities against these enzymes. Carbon 18-19 aldo-keto reductase family 1 member C4 Homo sapiens 29-33 25461829-8 2015 Further diversion of carbon flux into neutral lipid droplet formation was investigated by the overexpression of DGA1 or ARE1 and by the co-overexpression of a compatible lipase, TGL1, TGL3 or TGL5. Carbon 21-27 sterol acyltransferase Saccharomyces cerevisiae S288C 120-124 25588735-8 2015 Interestingly, starch and sucrose accumulation could be prevented and nitrate levels could be maintained by supplying the ppc1/ppc2 mutant with exogenous malate and glutamate, suggesting that low nitrogen status resulted in the alteration of carbon metabolism and prompted the accumulation of starch and sucrose in the ppc1/ppc2 mutant. Carbon 242-248 phosphoenolpyruvate carboxylase 1 Arabidopsis thaliana 122-126 17157197-1 2007 A yeast mutant lacking the two major cytosolic sources of NADPH, glucose-6-phosphate dehydrogenase (Zwf1p) and NADP+-specific isocitrate dehydrogenase (Idp2p), has been demonstrated to lose viability when shifted to medium with acetate or oleate as the carbon source. Carbon 253-259 glucose-6-phosphate dehydrogenase Saccharomyces cerevisiae S288C 65-98 25588735-8 2015 Interestingly, starch and sucrose accumulation could be prevented and nitrate levels could be maintained by supplying the ppc1/ppc2 mutant with exogenous malate and glutamate, suggesting that low nitrogen status resulted in the alteration of carbon metabolism and prompted the accumulation of starch and sucrose in the ppc1/ppc2 mutant. Carbon 242-248 phosphoenolpyruvate carboxylase 1 Arabidopsis thaliana 319-323 20932745-3 2010 Based on the in vitro results, SAR of this series of compounds requires an alkoxy substituent at the 6-position to be a straight and saturated chain up to three carbons long, since substitution of unsaturated and branched alkyloxy groups results in decrease in ET(A) antagonist activity. Carbon 161-168 sarcosine dehydrogenase Homo sapiens 31-34 17513896-4 2007 The RBE of carbon ions was estimated to be 2.0 to 3.0 along the SOBP for acute skin reactions. Carbon 11-17 sine oculis binding protein homolog Homo sapiens 64-68 20817737-6 2010 Integrity of both domains and their direct interaction are necessary for Maf1 dephosphorylation and subsequent inhibition of Pol III transcription on a nonfermentable carbon source. Carbon 167-173 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 73-77 20833733-5 2010 Heterologous expression of LeHT1 (and previously LeHT2, Gear et al., 2000), but not LeHT3, rescued a hexose transport-impaired yeast mutant when raised on glucose or fructose as the sole carbon source. Carbon 187-193 hexose transporter 1 Solanum lycopersicum 27-32 25253043-9 2015 Moreover, Pearson"s correlation analysis indicated that Actinobacteria was positively correlated with the levels of total alkalinity and dissolved organic carbon in tap water, while Firmicutes had a significant positive correlation with nitrite nitrogen. Carbon 155-161 nuclear RNA export factor 1 Homo sapiens 165-168 17214518-0 2007 Initial yields of DNA double-strand breaks and DNA Fragmentation patterns depend on linear energy transfer in tobacco BY-2 protoplasts irradiated with helium, carbon and neon ions. Carbon 159-165 F-box protein PP2-B11-like Nicotiana tabacum 118-122 25108199-4 2015 The biosensors were constructed by covalent immobilization of lactate oxidase (LOx) onto screen printed carbon electrodes (SPCEs) modified with PtNps (PtNps/GCNF-SPCEs) using polyethyleneimine (PEI) and glutaraldehyde (GA). Carbon 104-110 lysyl oxidase Homo sapiens 62-77 20827708-1 2010 Protective coating: Carbon-SnO(2) core-sheath composite nanofibers are synthesized through the creative combination of electrospinning and electrodeposition processes (see figure). Carbon 20-26 strawberry notch homolog 2 Homo sapiens 27-30 16990006-3 2006 Compounds 13 and 14 with a single carbon atom bridge are both substrates for folylpoly-gamma-glutamate synthetase (FPGS), the enzyme responsible for forming critical poly-gamma-glutamate antifolate metabolites with increased potency and/or increased cell retention. Carbon 34-40 folylpolyglutamate synthase Homo sapiens 77-113 20552676-2 2010 5,10-Methylenetetrahydrofolate reductase (MTHFR) is a crucial enzyme in folate-mediated one-carbon metabolism and folate deficiency can be associated with psychiatric symptoms. Carbon 92-98 methylenetetrahydrofolate reductase Homo sapiens 42-47 25488845-6 2015 In vitro binding assays of longer chain fluoroalkoxy derivatives revealed that the length of the carbon chain is an integral feature in MAO-B inhibitor potency and selectivity within this scaffold. Carbon 97-103 monoamine oxidase B Rattus norvegicus 136-141 25193420-5 2015 The anodic bacteria in the BES demonstrated abilities to utilize the PAM as the sole carbon and nitrogen source to generate electricity. Carbon 85-91 peptidylglycine alpha-amidating monooxygenase Homo sapiens 69-72 16990006-3 2006 Compounds 13 and 14 with a single carbon atom bridge are both substrates for folylpoly-gamma-glutamate synthetase (FPGS), the enzyme responsible for forming critical poly-gamma-glutamate antifolate metabolites with increased potency and/or increased cell retention. Carbon 34-40 folylpolyglutamate synthase Homo sapiens 115-119 25193420-8 2015 Structure analysis suggested the carbon chain of PAM was partially degraded in the BES, producing polymeric products with lower molecular weight. Carbon 33-39 peptidylglycine alpha-amidating monooxygenase Homo sapiens 49-52 20415720-6 2010 RESULTS: After cosensitization with OVA and low-dose poly(I:C), but not with high-dose poly(I:C), inflammation scores after allergen challenge were lower in IL-17-deficient mice than in wild-type (WT) mice. Carbon 60-61 interleukin 17A Mus musculus 157-162 17137366-0 2006 Synthetic studies toward (-)-FR901483 using a conjugate allylation to install the C-1 quaternary carbon. Carbon 97-103 heterogeneous nuclear ribonucleoprotein C Homo sapiens 82-85 17334057-6 2006 The marine basins, especially the outer basins, are dominated by large horizontal water fluxes that transport carbon and any associated contaminants into the Baltic Sea. Carbon 110-116 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 165-168 20369300-0 2010 A study on the prognostic evaluation of carbon ion radiotherapy for head and neck adenocarcinoma with C-11 methionine PET. Carbon 40-46 RNA polymerase III subunit K Homo sapiens 102-106 20428225-10 2010 The average cell-specific net carbon-fixation rate was 38 and 40 fmol C cell(-1) h(-1) measured by microsensors and by using stable isotopes in combination with mass spectrometry and nanoSIMS, respectively. Carbon 30-36 carboxyl ester lipase pseudogene Homo sapiens 72-79 25307054-2 2015 Sterol reductases including Delta(14)-sterol reductase (C14SR, also known as TM7SF2), 7-dehydrocholesterol reductase (DHCR7) and 24-dehydrocholesterol reductase (DHCR24) reduce specific carbon-carbon double bonds of the sterol moiety using a reducing cofactor during sterol biosynthesis. Carbon 186-192 transmembrane 7 superfamily member 2 Homo sapiens 77-83 25307054-2 2015 Sterol reductases including Delta(14)-sterol reductase (C14SR, also known as TM7SF2), 7-dehydrocholesterol reductase (DHCR7) and 24-dehydrocholesterol reductase (DHCR24) reduce specific carbon-carbon double bonds of the sterol moiety using a reducing cofactor during sterol biosynthesis. Carbon 186-192 7-dehydrocholesterol reductase Homo sapiens 118-123 25307054-2 2015 Sterol reductases including Delta(14)-sterol reductase (C14SR, also known as TM7SF2), 7-dehydrocholesterol reductase (DHCR7) and 24-dehydrocholesterol reductase (DHCR24) reduce specific carbon-carbon double bonds of the sterol moiety using a reducing cofactor during sterol biosynthesis. Carbon 193-199 transmembrane 7 superfamily member 2 Homo sapiens 77-83 25307054-2 2015 Sterol reductases including Delta(14)-sterol reductase (C14SR, also known as TM7SF2), 7-dehydrocholesterol reductase (DHCR7) and 24-dehydrocholesterol reductase (DHCR24) reduce specific carbon-carbon double bonds of the sterol moiety using a reducing cofactor during sterol biosynthesis. Carbon 193-199 7-dehydrocholesterol reductase Homo sapiens 118-123 17090927-8 2006 INO2-APL2 double disruptants also showed growth inability in non-fermentable carbon sources, such as glycerol. Carbon 77-83 Ino2p Saccharomyces cerevisiae S288C 0-4 25663847-6 2014 Distinct enzymes potentially participating in the carbon-concentrating mechanism (CAH7, CAH8, PEPC1) are strongly accumulated. Carbon 50-56 uncharacterized protein Chlamydomonas reinhardtii 82-86 25663847-6 2014 Distinct enzymes potentially participating in the carbon-concentrating mechanism (CAH7, CAH8, PEPC1) are strongly accumulated. Carbon 50-56 uncharacterized protein Chlamydomonas reinhardtii 94-99 20641017-8 2010 Altogether, these results suggest that YLR042c influences xylose and the assimilation of carbon sources other than glucose, and that the effect could be at the level of sugar transport or sugar signalling. Carbon 89-95 Nfg1p Saccharomyces cerevisiae S288C 39-46 20532304-0 2010 Structural characterization by confocal laser scanning microscopy and electrochemical study of multi-walled carbon nanotube tyrosinase matrix for phenol detection. Carbon 108-114 tyrosinase Homo sapiens 124-134 20532304-1 2010 A novel visualization methodology based on the use of immunofluorescence and Confocal Laser Scanning Microscopy (CLSM) was used to quantify and visualize tyrosinase enzyme within a MWCNTs matrix immobilized onto carbon based screen-printed electrodes. Carbon 212-218 tyrosinase Homo sapiens 154-164 17090927-8 2006 INO2-APL2 double disruptants also showed growth inability in non-fermentable carbon sources, such as glycerol. Carbon 77-83 Apl2p Saccharomyces cerevisiae S288C 5-9 16939325-3 2006 Experiments with various 13C-labeled glucose isotopomers in the presence of glycine revealed all six carbon atoms being incorporated into acetic acid: C-1/C-2 ( approximately 70%), C-3/C-4 ( approximately 10%), and C-5/C-6 (approximately 20%). Carbon 101-107 heterogeneous nuclear ribonucleoprotein C Homo sapiens 151-158 21587922-1 2010 In the title compound, C(13)H(11)Cl(2)NO(2)S, the conformation of the N-H bond in the C-SO(2)-NH-C segment is anti to the meta-Cl atom on the aniline ring and syn to the ortho-methyl group on the sulfonyl-benzene ring. Carbon 23-24 synemin Homo sapiens 159-162 25435132-2 2014 The nanocasting approach with a polycarbosilane precursor and subsequent pyrolysis, followed by silica template removal and chlorine treatment, results in carbide-derived carbons DUT-86 (DUT=Dresden University of Technology) with remarkable textural characteristics, monodisperse, spherical mesopores tunable in diameter, and very high pore volumes up to 5.0 cm3 g(-1). Carbon 171-178 deoxyuridine triphosphatase Homo sapiens 179-182 25435132-2 2014 The nanocasting approach with a polycarbosilane precursor and subsequent pyrolysis, followed by silica template removal and chlorine treatment, results in carbide-derived carbons DUT-86 (DUT=Dresden University of Technology) with remarkable textural characteristics, monodisperse, spherical mesopores tunable in diameter, and very high pore volumes up to 5.0 cm3 g(-1). Carbon 171-178 deoxyuridine triphosphatase Homo sapiens 187-190 16865333-0 2006 Amperometric determination of bovine insulin based on synergic action of carbon nanotubes and cobalt hexacyanoferrate nanoparticles stabilized by EDTA. Carbon 73-79 insulin Bos taurus 37-44 25346258-2 2014 The assignment of the absolute configuration of asymmetric carbon center C42 in two structurally complex epimeric substructures containing six stereocenters by VCD analysis illustrates the power and reliability of combining methods. Carbon 59-65 CDK5 regulatory subunit associated protein 1 Homo sapiens 73-76 20486702-2 2010 The reactions proceed with addition of the alkynes across the Ga-N-C fragment resulting in carbon-carbon and carbon-gallium bonds. Carbon 91-97 glucosidase alpha, neutral C Homo sapiens 62-68 20486702-2 2010 The reactions proceed with addition of the alkynes across the Ga-N-C fragment resulting in carbon-carbon and carbon-gallium bonds. Carbon 98-104 glucosidase alpha, neutral C Homo sapiens 62-68 20486702-2 2010 The reactions proceed with addition of the alkynes across the Ga-N-C fragment resulting in carbon-carbon and carbon-gallium bonds. Carbon 98-104 glucosidase alpha, neutral C Homo sapiens 62-68 20479116-5 2010 Polyinosine-polycytidylic acid (poly I:C)-activated CD141+ DCs have a superior capacity to cross-present soluble protein antigen (Ag) to CD8+ cytotoxic T lymphocytes than poly I:C-activated CD1c+ DCs. Carbon 39-40 CD8a molecule Homo sapiens 137-140 25415762-6 2014 The observed effects are localized within the binding pocket and close to retinal carbons C14 and C15. Carbon 82-89 placenta associated 8 Homo sapiens 98-101 16865333-2 2006 A sensitive amperometric biosensor for insulin has been prepared using glassy carbon electrodes by solubilization of carbon nanotubes (CNTs) in chitosan (CHIT) together with CoNPs synthesized by the new methodology. Carbon 78-84 insulin Bos taurus 39-46 25278359-1 2014 A novel multi-scale web of carbon micro/nanofibers (ACF/CNF) was prepared by the catalytic chemical vapor deposition (CCVD), in which CeO2 and Cu nanoparticles (NPs) were in-situ incorporated during a synthesis step. Carbon 27-33 NPHS1 adhesion molecule, nephrin Homo sapiens 56-59 16865333-2 2006 A sensitive amperometric biosensor for insulin has been prepared using glassy carbon electrodes by solubilization of carbon nanotubes (CNTs) in chitosan (CHIT) together with CoNPs synthesized by the new methodology. Carbon 117-123 insulin Bos taurus 39-46 19944462-4 2010 Methylation in four CpG pairs (C-223, C-243, C-254, and C-267) in the first intron of ZAP-70 is associated with repression of ZAP-70. Carbon 20-21 zeta chain of T cell receptor associated protein kinase 70 Homo sapiens 86-92 17048493-2 2006 The obtained PLC was verified by the Fourier transformed infrared (FT-IR) and carbon nuclear magnetic resonance (13C-NMR) spectroscopy and by the gel permeation chromatography (GPC). Carbon 78-84 heparan sulfate proteoglycan 2 Homo sapiens 13-16 19944462-4 2010 Methylation in four CpG pairs (C-223, C-243, C-254, and C-267) in the first intron of ZAP-70 is associated with repression of ZAP-70. Carbon 20-21 zeta chain of T cell receptor associated protein kinase 70 Homo sapiens 126-132 19944462-4 2010 Methylation in four CpG pairs (C-223, C-243, C-254, and C-267) in the first intron of ZAP-70 is associated with repression of ZAP-70. Carbon 31-32 zeta chain of T cell receptor associated protein kinase 70 Homo sapiens 86-92 19944462-4 2010 Methylation in four CpG pairs (C-223, C-243, C-254, and C-267) in the first intron of ZAP-70 is associated with repression of ZAP-70. Carbon 31-32 zeta chain of T cell receptor associated protein kinase 70 Homo sapiens 126-132 19944462-4 2010 Methylation in four CpG pairs (C-223, C-243, C-254, and C-267) in the first intron of ZAP-70 is associated with repression of ZAP-70. Carbon 31-32 zeta chain of T cell receptor associated protein kinase 70 Homo sapiens 86-92 19944462-4 2010 Methylation in four CpG pairs (C-223, C-243, C-254, and C-267) in the first intron of ZAP-70 is associated with repression of ZAP-70. Carbon 31-32 zeta chain of T cell receptor associated protein kinase 70 Homo sapiens 126-132 19944462-4 2010 Methylation in four CpG pairs (C-223, C-243, C-254, and C-267) in the first intron of ZAP-70 is associated with repression of ZAP-70. Carbon 31-32 zeta chain of T cell receptor associated protein kinase 70 Homo sapiens 86-92 19944462-4 2010 Methylation in four CpG pairs (C-223, C-243, C-254, and C-267) in the first intron of ZAP-70 is associated with repression of ZAP-70. Carbon 31-32 zeta chain of T cell receptor associated protein kinase 70 Homo sapiens 126-132 25479159-0 2014 Functional study of the Hap4-like genes suggests that the key regulators of carbon metabolism HAP4 and oxidative stress response YAP1 in yeast diverged from a common ancestor. Carbon 76-82 transcription factor HAP4 Saccharomyces cerevisiae S288C 24-28 25479159-0 2014 Functional study of the Hap4-like genes suggests that the key regulators of carbon metabolism HAP4 and oxidative stress response YAP1 in yeast diverged from a common ancestor. Carbon 76-82 transcription factor HAP4 Saccharomyces cerevisiae S288C 94-98 21579562-2 2010 Further, the conformation of the C=O bond is syn to the ortho-methyl group in the benzoyl ring. Carbon 33-34 synemin Homo sapiens 45-48 16928055-3 2006 Both the absolute and relative stereochemistry of milbemycin beta3 was introduced by two Sharpless asymmetric dihydroxylations, two pi-allylpalladium-catalyzed reductions, and an iridium-catalyzed hydrogen migration/Claisen rearrangement to install the C-12 stereocenter. Carbon 216-217 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 61-66 20132313-4 2010 Compounds with a longer side chain (8-16 carbons) resulted in greater inhibition of Pdr5p ATPase. Carbon 41-48 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 84-89 20132313-5 2010 Derivatives with side chains of 8-12 carbons that retained hydroxyl groups on the benzene ring extensively inhibited Pdr5p ATPase activity. Carbon 37-44 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 117-122 25902645-0 2014 [Determination of phenol in water by electrochemical tyrosinase biosensor based on ordered graphitized mesoporous carbon and evaluated by high performance liquid chromatography]. Carbon 114-120 tyrosinase Homo sapiens 53-63 25902645-1 2014 A novel electrochemical tyrosinase biosensor based on ordered graphitized mesoporous carbon (GMC) was obtained, which was used as a platform for phenol detection. Carbon 85-91 tyrosinase Homo sapiens 24-34 25326386-6 2014 We expressed human SV2A in hexose transport-deficient EBY.VW4000 yeast cells and demonstrated that these cells are able to grow on galactose-containing medium but not on other fermentable carbon sources. Carbon 188-194 synaptic vesicle glycoprotein 2A Homo sapiens 19-23 16828048-3 2006 Limited proteolysis of MAB007 with Lys-C led to a single cleavage at the C-terminus of a lysine residue in the hinge region of the heavy chain at position 222, generating free Fab and Fc fragments. Carbon 39-40 FA complementation group B Homo sapiens 176-179 25960930-3 2014 Poly-inosinic:cytidylic acid (poly I:C) treatment activated PKC-theta in NK cells depending on the presence of a soluble factor produced by a different splenocyte subset. Carbon 37-38 protein kinase C, theta Mus musculus 60-69 20501910-1 2010 The process of dark-induced senescence in plants is relatively poorly understood, but a functional electron-transfer flavoprotein/electron-transfer flavoprotein:ubiquinone oxidoreductase (ETF/ETFQO) complex, which supports respiration during carbon starvation, has recently been identified. Carbon 242-248 electron-transfer flavoprotein:ubiquinone oxidoreductase Arabidopsis thaliana 192-197 16893243-1 2006 Capillary phase transitions of linear (from C(1) to C(12)) and branched (C(5) isomers) alkanes in single-walled carbon nanotubes have been investigated using the gauge-cell Monte Carlo simulation. Carbon 0-1 complement C5 Homo sapiens 72-77 20349927-1 2010 We report the photoinduced peptide bond (C-N) of an amide unit and S-S bond fission mechanisms of the cyclic tetrapeptide [cyclo(Boc-Cys-Pro-Aib-Cys-OMe)] in methanol solvent by using high-level CASSCF/CASPT2/Amber quantum mechanical/molecular mechanical (QM/MM) calculations. Carbon 41-42 ANIB1 Homo sapiens 141-144 25385698-3 2014 Phenylalanine ammonia-lyase (PAL) is the first committed enzyme in the pathway; it diverts the central flux of carbon from primary metabolism to the synthesis of myriad phenolics. Carbon 111-117 peptidylglycine alpha-amidating monooxygenase Homo sapiens 0-27 25385698-3 2014 Phenylalanine ammonia-lyase (PAL) is the first committed enzyme in the pathway; it diverts the central flux of carbon from primary metabolism to the synthesis of myriad phenolics. Carbon 111-117 peptidylglycine alpha-amidating monooxygenase Homo sapiens 29-32 16874306-5 2006 Using isoelectric focusing, native mass spectrometry and resolving the crystal structure at 1.8 A resolution, we found that human CD1b is simultaneously associated with endogenous phosphatidylcholine (PC) and a 41-44 carbon atoms-long spacer molecule. Carbon 217-223 CD1b molecule Homo sapiens 130-134 25465606-6 2014 RESULTS: T3 increased TRalpha mRNA expression in P (1.91+-0.13, p<0.001), SI (2.14+-0.44, p<0.001) compared to C group (1+-0.08). Carbon 117-118 guanine nucleotide binding protein, alpha transducing 1 Mus musculus 22-29 25132602-1 2014 Serine hydroxymethyltransferase isoforms (SHMT1 & SHMT2alpha), which serve as scaffold protein for the formation of a multi-enzyme complex and generate one-carbon unit for the de novo thymidylate biosynthesis pathway during DNA synthesis, are vitamin B6 (VB6)-dependent enzyme. Carbon 160-166 serine hydroxymethyltransferase 1 (soluble) Mus musculus 42-47 20371980-0 2010 Serum level of expressed in renal carcinoma (ERC)/ mesothelin in rats with mesothelial proliferative lesions induced by multi-wall carbon nanotube (MWCNT). Carbon 131-137 ELKS/RAB6-interacting/CAST family member 1 Rattus norvegicus 45-48 20067583-4 2010 One compound bearing two dopamine (DA)-like pharmacophoric "heads" separated by an 8-carbon linker achieved an 82-fold gain in inhibition of [(3)H] 2beta-carbomethoxy-3beta-(4-fluorophenyl)-tropane (CFT) binding compared with DA itself; bivalent compounds with a 6-carbon linker and heterologous combinations of DA-, amphetamine- and beta-phenethylamine-like heads all resulted in considerable and comparable gains in DAT affinity. Carbon 85-91 solute carrier family 6 member 3 Homo sapiens 418-421 20067583-4 2010 One compound bearing two dopamine (DA)-like pharmacophoric "heads" separated by an 8-carbon linker achieved an 82-fold gain in inhibition of [(3)H] 2beta-carbomethoxy-3beta-(4-fluorophenyl)-tropane (CFT) binding compared with DA itself; bivalent compounds with a 6-carbon linker and heterologous combinations of DA-, amphetamine- and beta-phenethylamine-like heads all resulted in considerable and comparable gains in DAT affinity. Carbon 265-271 solute carrier family 6 member 3 Homo sapiens 418-421 16896244-0 2006 Direct electrochemical behavior of cytochrome c on DNA-modified glassy carbon electrode and its application to cytochrome c biosensor. Carbon 71-77 cytochrome c, somatic Equus caballus 35-47 19902960-9 2010 How close are the measurable properties of H(2)@C(60) to those computed for the "quantum particle in a spherical box"? Carbon 48-49 relaxin 2 Homo sapiens 43-47 20352728-1 2010 A uric acid biosensor has been fabricated through the immobilization of uricase on glassy carbon electrode modified by biomimetic titanate nanotubes of high specific surface area synthesized by hydrothermal decomposition. Carbon 90-96 urate oxidase (pseudogene) Homo sapiens 72-79 25513679-2 2014 The observed stereoselectivity shows a clear and systematic trend with anti:syn ratios increasing in line with the size of substituent at both the allylic stereocenter and double bond alpha-carbon. Carbon 190-196 synemin Homo sapiens 76-79 25248697-7 2014 For the biofuel cell application, EAPC-GOx and EAPC-LAC were applied over the carbon papers to form enzyme anode and cathode, respectively. Carbon 78-84 hydroxyacid oxidase 1 Homo sapiens 39-42 16896244-2 2006 The direct electron transfer of horse heart cytochrome c on DNA-modified glassy carbon electrode was achieved. Carbon 80-86 cytochrome c, somatic Equus caballus 44-56 16896244-5 2006 The DNA-modified glassy carbon electrode could be applied to detect cytochrome c by means of differential pulse voltammetry (DPV). Carbon 24-30 cytochrome c, somatic Equus caballus 68-80 16642262-6 2006 These results suggest that the mat microbial communities in deep-sea cold seep sediments at the northeastern Japan Sea are significantly responsible for sulfur and carbon circulations and the geological activity associated with plate movements serves unique microbial habitats in deep-sea environments. Carbon 164-170 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 65-68 25282359-5 2014 Notably, pharmacologic inhibition or T cell-specific deletion of ACC1 not only blocks de novo fatty acid synthesis but also interferes with the metabolic flux of glucose-derived carbon via glycolysis and the tricarboxylic acid cycle. Carbon 178-184 acetyl-CoA carboxylase alpha Homo sapiens 65-69 20010828-6 2010 The electric modification of the spin polarization relies on discrete states in the Si with a Zeeman spin splitting, an approach that is also applicable to organic, carbon-based and other materials with weak spin-orbit interaction. Carbon 165-171 spindlin 1 Homo sapiens 33-37 20010828-6 2010 The electric modification of the spin polarization relies on discrete states in the Si with a Zeeman spin splitting, an approach that is also applicable to organic, carbon-based and other materials with weak spin-orbit interaction. Carbon 165-171 spindlin 1 Homo sapiens 101-105 20010828-6 2010 The electric modification of the spin polarization relies on discrete states in the Si with a Zeeman spin splitting, an approach that is also applicable to organic, carbon-based and other materials with weak spin-orbit interaction. Carbon 165-171 spindlin 1 Homo sapiens 101-105 20641630-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Carbon 19-20 gastrin releasing peptide Homo sapiens 65-73 20641630-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Carbon 19-20 gastrin releasing peptide Homo sapiens 94-102 25248862-0 2014 Dual-colored graphene quantum dots-labeled nanoprobes/graphene oxide: functional carbon materials for respective and simultaneous detection of DNA and thrombin. Carbon 81-87 coagulation factor II, thrombin Bos taurus 151-159 16642262-6 2006 These results suggest that the mat microbial communities in deep-sea cold seep sediments at the northeastern Japan Sea are significantly responsible for sulfur and carbon circulations and the geological activity associated with plate movements serves unique microbial habitats in deep-sea environments. Carbon 164-170 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 115-118 25248862-2 2014 Herein, we report the respective and simultaneous detection of DNA and bovine alpha-thrombin (thrombin) entirely based on biocompatible carbon materials through a specially designed fluorescence on-off-on process. Carbon 136-142 coagulation factor II, thrombin Bos taurus 78-92 25248862-2 2014 Herein, we report the respective and simultaneous detection of DNA and bovine alpha-thrombin (thrombin) entirely based on biocompatible carbon materials through a specially designed fluorescence on-off-on process. Carbon 136-142 coagulation factor II, thrombin Bos taurus 84-92 20641630-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Carbon 19-20 gastrin releasing peptide Homo sapiens 166-191 20641630-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Carbon 19-20 gastrin releasing peptide Homo sapiens 193-196 20641630-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-Glu-c(RGDyK)-bombesin[7-14] The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Carbon 19-20 gastrin releasing peptide Homo sapiens 241-244 16830093-4 2006 In the enzyme serine hydroxymethyltransferase (SHMT or GlyA protein), which links amino acid and nucleotide metabolisms by generating the key intermediate for one-carbon transfer reactions, two conserved inserts of 3 and 31 amino acids (aa) are uniquely present in various chlamydiae species as well as in a subset of Actinobacteria and in the Treponema species. Carbon 163-169 serine hydroxymethyltransferase 1 Homo sapiens 47-51 20041631-3 2010 The as-prepared P25-graphene photocatalyst possessed great adsorptivity of dyes, extended light absorption range, and efficient charge separation properties simultaneously, which was rarely reported in other TiO(2)-carbon photocatalysts. Carbon 215-221 tubulin polymerization promoting protein Homo sapiens 16-19 20041631-4 2010 Hence, in the photodegradation of methylene blue, a significant enhancement in the reaction rate was observed with P25-graphene, compared to the bare P25 and P25-CNTs with the same carbon content. Carbon 181-187 tubulin polymerization promoting protein Homo sapiens 115-118 24998673-8 2014 The quaternary structures for the S57K/N59E/E73K/S102D and S57K/N59E/E73K/S102D/H74K/D78P/D80E/D87G mutants of c-NADP-ME are tetrameric, whereas the K57S/E59N/K73E/D102S m-NAD(P)-ME quadruple mutant is primarily monomeric with some dimer formation. Carbon 19-20 malic enzyme 1 Homo sapiens 113-120 16707085-1 2006 Lanthanum hydroxide nanowires modified carbon paste electrode (LNW/CPE) exhibiting an electrocatalytic response toward the oxidation of mefenamic acid (MFA) is described. Carbon 39-45 carboxypeptidase E Homo sapiens 67-70 16751533-3 2006 The XYL2-disrupted mutant, BSXDH-3, did not grow on a minimal medium containing d-xylose as a sole carbon source. Carbon 99-105 D-xylulose reductase XYL2 Saccharomyces cerevisiae S288C 4-8 25225399-7 2014 DCs from old mice were deficient in poly I:C-stimulated secretion of IL-15, IL-18, and IFN-alpha. Carbon 1-2 interleukin 15 Mus musculus 69-74 25225399-7 2014 DCs from old mice were deficient in poly I:C-stimulated secretion of IL-15, IL-18, and IFN-alpha. Carbon 1-2 interferon alpha Mus musculus 87-96 25156478-7 2014 The origin of the unusually short Hal-C bonds is discussed in detail. Carbon 38-39 histidine ammonia-lyase Homo sapiens 34-37 19957936-6 2010 Rather than regeneration of initial complex 1 after the light-induced H(2)O(2) evolution in the catalytic cycle, the DFT calculations predict a new route with a lower energy barrier via the regeneration of 1", an isomer of 1 with the unsaturated carbon at the nitrogen side arm of the PNN ligand. Carbon 246-252 pinin, desmosome associated protein Homo sapiens 285-288 19799901-12 2010 RNA interference indicates that the polyI:C-induced PGLYRP-2 was dramatically blocked in the cells transfected with siRNA-TRIF but neither siRNA-MyD88 nor the negative control siRNA-F. Carbon 42-43 peptidoglycan recognition protein 2 Homo sapiens 52-60 16771592-0 2006 Nanoscale uniaxial pressure effect of a carbon nanotube bundle on tip-enhanced near-field Raman spectra. Carbon 40-46 TOR signaling pathway regulator Homo sapiens 66-69 19822655-5 2010 We demonstrated that fadA5 is required for utilization of cholesterol as a sole carbon source in vitro and for full virulence of M. tuberculosis in the chronic stage of mouse lung infection. Carbon 80-86 acetyl-CoA acetyltransferase FadA Mycobacterium tuberculosis H37Rv 21-26 20351421-1 2010 Low cost and large scale carbon nanotube and nanofibre (CNT-CNF) composite films have been fabricated and employed as electrodes for electrosorption of cupric ions. Carbon 25-31 NPHS1 adhesion molecule, nephrin Homo sapiens 60-63 16771592-1 2006 In situ measurement of tip-enhanced near-field Raman spectra of an isolated single-wall carbon nanotube (SWNT) bundle has been demonstrated by applying a uniaxial pressure up to approximately 2 GPa to the bundle via a metal-coated atomic force microscope tip. Carbon 88-94 TOR signaling pathway regulator Homo sapiens 23-26 25171328-0 2014 Trap-state-dominated suppression of electron conduction in carbon nanotube thin-film transistors. Carbon 59-65 TRAP Homo sapiens 0-4 16516473-0 2006 Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: synthesis and structure-activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inhibitors. Carbon 37-43 epidermal growth factor Homo sapiens 148-151 25171328-3 2014 On the basis of the above observation, we conclude that the environmental adsorbates work by more than simply shifting the Fermi level of the CNTs; more importantly, these adsorbates cause a poor gate modulation efficiency of electron conduction due to the relatively large trap state density near the conduction band edge of the carbon nanotubes, for which we further propose quantitatively that the adsorbed oxygen-water redox couple is responsible. Carbon 330-336 TRAP Homo sapiens 274-278 25162977-7 2014 The residual carbon chain did not decompose completely at temperatures less than 550 C. We proposed a PVP-assisted Ostwald ripening mechanism for the formation of SnO2 NTs. Carbon 13-19 strawberry notch homolog 2 Homo sapiens 164-167 19847013-4 2009 ICL is a key enzyme of the glyoxylate cycle that allows growth on acetate as a sole source of carbon. Carbon 94-100 uncharacterized protein Chlamydomonas reinhardtii 0-3 21580141-3 2009 The benzene-connected portions of the alk-oxy substituents lie almost coplanar with the ring [C-O-C-C torsion angle = 2.0 (2) ]. Carbon 94-96 ALK receptor tyrosine kinase Homo sapiens 38-41 21580141-3 2009 The benzene-connected portions of the alk-oxy substituents lie almost coplanar with the ring [C-O-C-C torsion angle = 2.0 (2) ]. Carbon 94-95 ALK receptor tyrosine kinase Homo sapiens 38-41 21580141-3 2009 The benzene-connected portions of the alk-oxy substituents lie almost coplanar with the ring [C-O-C-C torsion angle = 2.0 (2) ]. Carbon 98-99 ALK receptor tyrosine kinase Homo sapiens 38-41 16770047-1 2006 Choline can be covalently grafted on glassy carbon electrodes using cyclic voltammetric method, forming a stable cationic monolayer-modified electrode (Ch/GCE). Carbon 44-50 aminomethyltransferase Homo sapiens 155-158 19719479-3 2009 Here, it is shown that WRI1 acts as a transcriptional enhancer of genes involved in carbon metabolism in transgenic seeds overexpressing this transcription factor. Carbon 84-90 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 23-27 25149512-2 2014 We recently developed non-secosteroidal VDR ligands based on a carbon-containing boron cluster, 1,12-dicarba-closo-dodecaborane (p-carborane), and examined the binding of one of them to VDR by means of crystallographic analysis. Carbon 63-69 vitamin D receptor Homo sapiens 40-43 19815185-1 2009 Reactions of amines and carbon nucleophiles with 4-sulfonyl-hex-3-enopyranoside generate a range of C-3 amino- and C-3 branched-chain sugars, which are analogues of 3-amino-3,6-dideoxy sugars and 3-C-branched-chain-3,6-dideoxy sugars. Carbon 24-30 complement C3 Homo sapiens 100-118 16376104-5 2006 While TbetaM efficiently hydroxylates the aliphatic carbon of phenolic amines such as tyramine (the physiological substrate) and dopamine, phenethylamine is a poor substrate. Carbon 52-58 Tyramine beta hydroxylase Drosophila melanogaster 6-12 19852486-0 2009 Dip-pen nanolithography of electrical contacts to single-walled carbon nanotubes. Carbon 64-70 DIP Homo sapiens 0-3 19852486-1 2009 This paper discusses a method for the direct patterning of Au electrodes at nanoscale resolution using dip-pen nanolithography, with proof-of-concept demonstrated by creating single-walled carbon nanotube devices. Carbon 189-195 DIP Homo sapiens 103-106 19852486-2 2009 This technique enables insight into three key concepts at the nanoscale: using dip-pen nanolithography as an alternative to electron-beam lithography for writing contacts to carbon nanotubes, understanding the integrity of contacts and devices patterned with this technique, and on a more fundamental level, providing a facile method to compare and understand electrical and Raman spectroscopy data from the same isolated carbon nanotube. Carbon 174-180 DIP Homo sapiens 79-82 19852486-2 2009 This technique enables insight into three key concepts at the nanoscale: using dip-pen nanolithography as an alternative to electron-beam lithography for writing contacts to carbon nanotubes, understanding the integrity of contacts and devices patterned with this technique, and on a more fundamental level, providing a facile method to compare and understand electrical and Raman spectroscopy data from the same isolated carbon nanotube. Carbon 422-428 DIP Homo sapiens 79-82 19852486-3 2009 Electrical contacts to individual and small bundle single-walled carbon nanotubes were masked by an alkylthiol that was deposited via dip-pen nanolithography on a thin film of Au evaporated onto spin-cast, nonpercolating, and highly isolated single-walled carbon nanotubes. Carbon 65-71 DIP Homo sapiens 134-137 19852486-8 2009 The merits of using dip-pen nanolithography include flexible device configuration (such as varying the channel length and the number, size, and orientation of contacts), targeted patterning of individual devices with imaging and writing conducted in the same instrument under ambient conditions, and negligible damage to single-walled carbon nanotubes during the fabrication process. Carbon 335-341 DIP Homo sapiens 20-23 25044145-1 2014 Electronic effects on the central carbon atom of carbone, generated by the replacement of the S(IV) ligand of carbodisulfane (CDS) with other chalcogen ligands (Ph2 E, E=S or Se), were investigated. Carbon 49-56 polyhomeotic homolog 2 Homo sapiens 161-164 25044145-2 2014 The carbones Ph2 E C SPh2 (NMe) [E=S(1) or Se(2)] were synthesized from the corresponding salts, and their molecular structures and electronic properties were characterized. Carbon 4-12 polyhomeotic homolog 2 Homo sapiens 13-16 25044145-2 2014 The carbones Ph2 E C SPh2 (NMe) [E=S(1) or Se(2)] were synthesized from the corresponding salts, and their molecular structures and electronic properties were characterized. Carbon 4-12 ankyrin 1 Homo sapiens 21-25 25108300-1 2014 Several unnatural derivatives of narciclasine were prepared in which the C-7 carbon was replaced with nitrogen. Carbon 77-83 complement C7 Homo sapiens 73-76 21578849-1 2009 In the title compound, C(15)H(12)ClNO(2), the two benzene rings adopt a syn configuration with respect to the ep-oxy ring; the dihedral angles between the ep-oxy ring and the two benzene rings are 59.71 (16) and 67.58 (15) . Carbon 23-25 synemin Homo sapiens 72-75 16608354-1 2006 The carbon-nitrogen bond of secondary carboxamides is generally thermodynamically and kinetically unreactive; however, we recently discovered that the trisamidoaluminum(III) dimer Al2(NMe2)6 catalyzes facile transamidation between simple secondary carboxamides and primary amines under moderate conditions. Carbon 4-10 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 184-188 19627075-3 2009 The carbon adsorbents were characterized with TEM, XRD, Raman spectroscopy, and nitrogen adsorption apparatus for their physical and chemical properties, and evaluated for their hydrogen adsorption equilibria and kinetics at 298 K and hydrogen pressures up to 300 bar. Carbon 4-10 MFT2 Homo sapiens 46-49 16455667-4 2006 The ESR hyperfine splittings of spin-labeled phospholipid probes revealed that alpha-synuclein induces chain ordering at carbon 14 of the acyl chains below the chain melting phase transition temperature but not in the liquid crystalline state of electroneutral vesicle membranes. Carbon 121-127 synuclein alpha Homo sapiens 79-94 19535301-0 2009 Direct electron transfer of glucose oxidase immobilized in an ionic liquid reconstituted cellulose-carbon nanotube matrix. Carbon 99-105 hydroxyacid oxidase 1 Homo sapiens 28-43 19535301-2 2009 Glucose oxidase (GOx) was encapsulated in this matrix and thereby immobilized on a glassy carbon surface. Carbon 90-96 hydroxyacid oxidase 1 Homo sapiens 0-15 19535301-2 2009 Glucose oxidase (GOx) was encapsulated in this matrix and thereby immobilized on a glassy carbon surface. Carbon 90-96 hydroxyacid oxidase 1 Homo sapiens 17-20 25077795-1 2014 The transcription of the Arabidopsis (Arabidopsis thaliana) GATA transcription factors GATA, NITRATE-INDUCIBLE, CARBON METABOLISM-INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 is controlled by several growth regulatory signals including light and the phytohormones auxin, cytokinin, and gibberellin. Carbon 112-118 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 60-64 16570967-1 2006 Several samples of palladium-loaded single-wall carbon nanotubes and palladium-loaded MAXSORB activated carbon were prepared by means of the reaction of the raw carbon support with Pd2(dba)3.CHCl3. Carbon 104-110 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 181-184 25099331-2 2014 The effect of polymer composition on the properties of the carbon dots was investigated by TEM, IR, XPS, elemental analysis and fluorescence analysis, with carbon dots synthesised from nitrogen-containing polymers showing the highest fluorescence. Carbon 59-65 MFT2 Homo sapiens 91-94 25099331-2 2014 The effect of polymer composition on the properties of the carbon dots was investigated by TEM, IR, XPS, elemental analysis and fluorescence analysis, with carbon dots synthesised from nitrogen-containing polymers showing the highest fluorescence. Carbon 156-162 MFT2 Homo sapiens 91-94 24992071-6 2014 Herein, we report on the development of a new class of cationic lipid-Dex conjugates in which the C-8 carbon chain analogue (DX8) exhibited glucocorticoid receptor (GR)-mediated, caspase-3-assisted, cancer cell-selective anti-proliferative activity. Carbon 102-108 cell division cycle associated 3 Mus musculus 98-101 25133402-7 2014 Quantitative comparison revealed that MFGM proteins were up- or down-regulated more than twofold in the TC and C groups compared to N group: 126 in colostrum and 77 in mature milk of the TC-LA group; 157 in colostrum and 222 in mature milk of the TC-LF group; 49 in colostrum and 98 in mature milk of the TC-LZ group; 98 in colostrum and 132 in mature milk in the C group. Carbon 105-106 milk fat globule EGF and factor V/VIII domain containing Bos taurus 38-42 19277739-5 2009 The AtP4H1oexp plants showed hypoxia-in-normoxia phenotype with strict requirement for carbon source for its growth, increased root hair, absence of trichome, and reduction in seed size. Carbon 87-93 P4H Arabidopsis thaliana 4-10 19824901-7 2009 It was concluded that isolate Eu-32 is a unique desulphurizing biocatalyst that desulphurizes dibenzothiophene through an extended, sulphur-specific degradation pathway with the selective cleavage of C-S bonds. Carbon 200-201 E74 like ETS transcription factor 2 Homo sapiens 30-35 16570967-1 2006 Several samples of palladium-loaded single-wall carbon nanotubes and palladium-loaded MAXSORB activated carbon were prepared by means of the reaction of the raw carbon support with Pd2(dba)3.CHCl3. Carbon 104-110 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 181-184 16397765-5 2006 We demonstrated that HXT5, HXT13 and, to a lesser extent, HXT15 were all induced in the presence of non-fermentable carbon sources. Carbon 116-122 hexose transporter HXT5 Saccharomyces cerevisiae S288C 21-25 19643844-6 2009 Additional experiments demonstrated that pH-induced migration of the O-acetyl modification from the 7- to 9-carbon position had a substantial impact on GBS-Siglec-9 interactions, with 7-O-acetylation exhibiting the strongest interference. Carbon 108-114 sialic acid binding Ig like lectin 9 Homo sapiens 156-164 19594710-6 2009 Thus, WRI1 promotes the flow of carbon to oil during seed maturation by directly activating genes involved in FA synthesis and controlling genes for assembly and storage of TAG. Carbon 32-38 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 6-10 32262273-0 2014 Sn-Fe cyanogels noncovalently grafted to carbon nanotubes in a versatile biointerface design: an efficient matrix and a facile platform for glucose oxidase immobilization. Carbon 41-47 hydroxyacid oxidase 1 Homo sapiens 140-155 16491186-1 2006 The present study demonstrates that for the nanocasting process with zeolites, a careful choice of the zeolite structure type (EMT) allows the formation of faithful carbon replica exhibiting up to three well resolved XRD peaks. Carbon 165-171 IL2 inducible T cell kinase Homo sapiens 127-130 24726863-2 2014 AS3MT activity requires the presence of the methyl donor S-adenosylmethionine, a product of folate-dependent one-carbon metabolism, and a reductant. Carbon 113-119 arsenite methyltransferase Homo sapiens 0-5 20137409-5 2009 (2) Compared with control group after exposed for 30 days, the expression of ET-1 mRNA [B group:(17.39 +/- 4.59) x 104; C group: (36.21 +/- 13.13) x 104 ] were much higher and expression of eNOS mRNA [A group: (19.11 +/- 6.83) x 104; B group: (11.86 +/- 3.15) x 104; C group: (4.68 +/- 3.26) x 104] was much lower, there were significant differences (P < 0.01). Carbon 4-5 endothelin-1 Oryctolagus cuniculus 77-81 16536979-1 2006 BACKGROUND & OBJECTIVE: Serine hydroxymethyltransferase (SHMT), a key enzyme in the folate metabolism, affects gene methylation and DNA synthesis through providing one-carbon units for purine, thymidylate, and methionine. Carbon 172-178 serine hydroxymethyltransferase 1 Homo sapiens 28-59 20137409-5 2009 (2) Compared with control group after exposed for 30 days, the expression of ET-1 mRNA [B group:(17.39 +/- 4.59) x 104; C group: (36.21 +/- 13.13) x 104 ] were much higher and expression of eNOS mRNA [A group: (19.11 +/- 6.83) x 104; B group: (11.86 +/- 3.15) x 104; C group: (4.68 +/- 3.26) x 104] was much lower, there were significant differences (P < 0.01). Carbon 4-5 nitric oxide synthase, endothelial Oryctolagus cuniculus 190-194 19778056-6 2009 On the basis of the proposed mechanism, the glyoxal interaction with alanine through a decarboxylative aldol addition reaction can lead to the formation of 1,2-butanedione with the terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine, and the similar interaction of 1,2-butanedione with a second molecule of alanine can lead to the formation of 3,4-hexanedione with both terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine. Carbon 409-415 complement C3 Homo sapiens 235-238 19778056-6 2009 On the basis of the proposed mechanism, the glyoxal interaction with alanine through a decarboxylative aldol addition reaction can lead to the formation of 1,2-butanedione with the terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine, and the similar interaction of 1,2-butanedione with a second molecule of alanine can lead to the formation of 3,4-hexanedione with both terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine. Carbon 409-415 complement C3 Homo sapiens 448-451 19774287-3 2009 In this study, the role of the interplay between solvent water and nitrogen (MEA)-carbon (CO2) bond formation is discussed based on the molecular theory using RISM-SCF-SEDD, which is the hybrid method of quantum chemistry of solute and statistical mechanics of solvent. Carbon 82-88 KIT ligand Homo sapiens 164-167 24971830-3 2014 For short carbon alkyl chains (n < 3), the PIL structure is affected from intramolecular interaction caused from the induction effect (+I) due to the chain substituent of the imidazolium ring, while for PILs with n > 3 the van der Waals forces between the chains and pi-pi interaction between neighboring imidazolium rings become important. Carbon 10-16 serpin family A member 2 (gene/pseudogene) Homo sapiens 46-49 24325846-6 2014 The organic carbon normalized partition coefficient (Koc) increased by 0.51 log units for each additional CF2 moiety from perfluoro-butanesulfonate (PFBS) to PFOS. Carbon 12-18 ATPase H+ transporting accessory protein 1 Homo sapiens 106-109 19705847-9 2009 We also conclude from the liposome oxidations that linoleate peroxyl radicals at different positions on the eighteen-carbon chain (at C-9 and C-13) have different kinetic properties. Carbon 117-123 complement C9 Homo sapiens 134-137 16536979-1 2006 BACKGROUND & OBJECTIVE: Serine hydroxymethyltransferase (SHMT), a key enzyme in the folate metabolism, affects gene methylation and DNA synthesis through providing one-carbon units for purine, thymidylate, and methionine. Carbon 172-178 serine hydroxymethyltransferase 1 Homo sapiens 61-65 16487345-9 2006 The only exception was following carbon starvation, where Gat1, like Gln3, is hyperphosphorylated in a Snf1-dependent manner. Carbon 33-39 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 69-73 19703305-8 2009 Genes involved in central carbon metabolism (including several TCA cycle genes) and amino acid biosynthesis, as well as genes encoding nutrient transport systems are among those whose transcript levels are most significantly affected by CRP* expression.We present a detailed transcription analysis and relate these results to phenotypic differences between strains expressing wild-type CRP and CRP*. Carbon 26-32 catabolite gene activator protein Escherichia coli 237-240 24838670-1 2014 Direct metal-free C-4-selective indolation of pyridines is achieved for the first time using TEMPO and (Boc)2O. Carbon 18-19 BOC cell adhesion associated, oncogene regulated Homo sapiens 104-107 16491444-4 2006 Due to different carbon chains attached to C-9 of the pyrroloazepine nucleus they were classified into stichoneurine-, protostemonine- and croomine-type alkaloids. Carbon 17-23 complement component C9 Cavia porcellus 43-46 25009547-6 2014 Large-scale transcriptome analyses revealed that ATG8e belongs to a core carbon signaling response shared by Arabidopsis accessions, and the transcription of Arabidopsis ATG7 is tightly co-regulated with genes functioning in chlorophyll degradation and leaf senescence. Carbon 73-79 ThiF family protein Arabidopsis thaliana 170-174 19288150-0 2009 Gastric cancer in relation to the intake of nutrients involved in one-carbon metabolism among MTHFR 677 TT carriers. Carbon 70-76 methylenetetrahydrofolate reductase Homo sapiens 94-99 16833119-0 2006 Nanoscale imaging of carbon nanotubes using tip enhanced Raman spectroscopy in reflection mode. Carbon 21-27 TOR signaling pathway regulator Homo sapiens 44-47 21583670-1 2009 The conformation of the N-H bond in the structure of the title compound, C(8)H(7)BrClNO, is syn to the 2-chloro substituent in the aniline ring and anti to both the C=O and C-Br bonds in the side chain, similar to that observed in 2-chloro-N-(2-chloro-phen-yl)acetamide. Carbon 73-74 synemin Homo sapiens 92-95 21583670-1 2009 The conformation of the N-H bond in the structure of the title compound, C(8)H(7)BrClNO, is syn to the 2-chloro substituent in the aniline ring and anti to both the C=O and C-Br bonds in the side chain, similar to that observed in 2-chloro-N-(2-chloro-phen-yl)acetamide. Carbon 83-84 synemin Homo sapiens 92-95 19842489-3 2009 Therefore, the carbon atom within both these systems, being in its atomic state, can have one or two lone electron pairs and, as a result, it may form hydrogen bonds of the type D-H...CL2, where C acts as a proton acceptor. Carbon 15-21 endogenous retrovirus group W member 5 Homo sapiens 184-187 18682255-8 2009 Smaller effects were also seen for one-carbon metabolism genes choline dehydrogenase (CHDH) (rs9001, rs7626693) and 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) (rs1801394) and genes involved in reduction reactions, glutaredoxin (GLRX) (rs3822751) and peroxiredoxin 2 (PRDX2) (rs10427027, rs12151144). Carbon 39-45 choline dehydrogenase Homo sapiens 63-84 18682255-8 2009 Smaller effects were also seen for one-carbon metabolism genes choline dehydrogenase (CHDH) (rs9001, rs7626693) and 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR) (rs1801394) and genes involved in reduction reactions, glutaredoxin (GLRX) (rs3822751) and peroxiredoxin 2 (PRDX2) (rs10427027, rs12151144). Carbon 39-45 choline dehydrogenase Homo sapiens 86-90 18682255-10 2009 CONCLUSIONS: Polymorphisms in AS3MT and in genes involved in one-carbon metabolism and reduction reactions affects arsenic metabolism. Carbon 65-71 arsenite methyltransferase Homo sapiens 30-35 25002864-8 2014 Our results suggest that MGD3 plays an important role in supplying DGDG as a component of extraplastidial membranes to support enhanced plant growth under conditions of carbon excess. Carbon 169-175 monogalactosyldiacylglycerol synthase type C Arabidopsis thaliana 25-29 24480132-0 2014 Quantitative electrochemical detection of cathepsin B activity in complex tissue lysates using enhanced AC voltammetry at carbon nanofiber nanoelectrode arrays. Carbon 122-128 cathepsin B Homo sapiens 42-53 16207701-11 2006 Several proteins with diverse functions outside primary carbon metabolism, such as the isomerase ROC4, lipoxygenase 2 involved in jasmonic acid biosynthesis, and a carbonic anhydrase (CA1), were surprisingly abundant in the range of 0.75-1.5% of the total stromal mass. Carbon 56-62 lipoxygenase 2 Arabidopsis thaliana 103-117 24480132-1 2014 The proteolytic activity of a cancer-related enzyme cathepsin B is measured with alternating current voltammetry (ACV) using ferrocene (Fc) labeled tetrapeptides attached to nanoelectrode arrays (NEAs) fabricated with vertically aligned carbon nanofibers (VACNFs). Carbon 237-243 cathepsin B Homo sapiens 52-63 24534552-0 2014 Disposable amperometric biosensor based on lactate oxidase immobilised on platinum nanoparticle-decorated carbon nanofiber and poly(diallyldimethylammonium chloride) films. Carbon 106-112 lysyl oxidase Homo sapiens 43-58 24708375-3 2014 By targeting CD44-overexpressing MDR cancer cells, we have developed in a single-step a self-assembled, self-targetable, therapeutic semiconducting single-walled carbon nanotube (sSWCNT) drug delivery system that can deliver chemotherapeutic agents to both drug-sensitive OVCAR8 and resistant OVCAR8/ADR cancer cells. Carbon 162-168 CD44 molecule (Indian blood group) Homo sapiens 13-17 19447980-6 2009 Increasing the chain length increased the difference (i.e., MIR minus reference) between MIR prediction and reference chemistry by 0.0429% and by -0.0566% fat per unit of increase in carbon number per 1% change in fat, for fat B and fat A, respectively. Carbon 183-189 membrane associated ring-CH-type finger 8 Homo sapiens 60-63 19447980-6 2009 Increasing the chain length increased the difference (i.e., MIR minus reference) between MIR prediction and reference chemistry by 0.0429% and by -0.0566% fat per unit of increase in carbon number per 1% change in fat, for fat B and fat A, respectively. Carbon 183-189 membrane associated ring-CH-type finger 8 Homo sapiens 89-92 19329666-1 2009 Engineered Saccharomyces cerevisiae strains overexpressing GPD1, which codes for glycerol-3-phosphate dehydrogenase, and lacking the acetaldehyde dehydrogenase Ald6 display large-scale diversion of the carbon flux from ethanol toward glycerol without accumulating acetate. Carbon 202-208 glycerol-3-phosphate dehydrogenase (NAD(+)) GPD1 Saccharomyces cerevisiae S288C 59-63 16207701-11 2006 Several proteins with diverse functions outside primary carbon metabolism, such as the isomerase ROC4, lipoxygenase 2 involved in jasmonic acid biosynthesis, and a carbonic anhydrase (CA1), were surprisingly abundant in the range of 0.75-1.5% of the total stromal mass. Carbon 56-62 carbonic anhydrase 1 Arabidopsis thaliana 184-187 19144510-3 2009 5,10-Methylenetetrahydrofolate reductase (MTHFR), a key enzyme of one-carbon metabolism, catalyses the irreversible conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. Carbon 70-76 methylenetetrahydrofolate reductase Homo sapiens 0-40 16698969-0 2006 Response of LiF:Mg,Ti to low energy carbon and oxygen ions. Carbon 36-42 LIF interleukin 6 family cytokine Homo sapiens 12-15 19450180-3 2009 The MTHFR SNPs are ideal candidates for investigating the role of SNPs in cancer risk modification and treatment because of their well-defined and highly relevant biochemical effects on intracellular folate composition and one-carbon transfer reactions. Carbon 227-233 methylenetetrahydrofolate reductase Homo sapiens 4-9 24361422-1 2014 An ultrasensitive electrochemical immunoassay was developed for rapid detection of interleukin-6 (IL-6) and matrix metallopeptidase-9 (MMP-9); the method utilized PS@PDA-metal nanocomposites based on graphene nanoribbon (GNR)-modified heated screen-printed carbon electrode (HSPCE). Carbon 257-263 matrix metallopeptidase 9 Homo sapiens 135-140 17165463-1 2006 The feasibility of anaerobic packed bed reactors with tezontle (volcanic stone widely available in Mexico) and mineral granular activated carbon (GAC) was explored for the degradation of the main chlorinated aliphatic compounds present in the effluent from chemical industry for ethylene and polyvinyl chloride production. Carbon 138-144 glutaminase Homo sapiens 146-149 24689702-2 2014 Prefunctionalization before ALD, as required for initiating covalent bonding on a carbon nanotube surface, was eliminated on VACNFs due to the graphitic edges along the surface of each CNF. Carbon 82-88 NPHS1 adhesion molecule, nephrin Homo sapiens 127-130 19389261-1 2009 BACKGROUND: Several studies have determined that dietary intake of B vitamins may be associated with breast cancer risk as a result of interactions between 5,10-methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR) in the one-carbon metabolism pathway. Carbon 246-252 methylenetetrahydrofolate reductase Homo sapiens 156-196 19389261-1 2009 BACKGROUND: Several studies have determined that dietary intake of B vitamins may be associated with breast cancer risk as a result of interactions between 5,10-methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR) in the one-carbon metabolism pathway. Carbon 246-252 methylenetetrahydrofolate reductase Homo sapiens 198-203 16304645-6 2005 In the diol dehydratases the 5"-deoxyadenosyl radical generated by homolysis of the carbon-cobalt bond of coenzyme B12 moves about 10 A away from the cobalt atom in cob(II)alamin. Carbon 84-90 metabolism of cobalamin associated B Homo sapiens 91-94 24591463-0 2014 Diels-Alder/oxidative aromatization approach towards the all-carbon DEF tricyclic skeleton of daphenylline. Carbon 61-67 UTP25 small subunit processome component Homo sapiens 68-71 24591463-2 2014 In this study, the synthesis of the fused all-carbon DEF tricyclic skeleton of daphenylline has been accomplished. Carbon 46-52 UTP25 small subunit processome component Homo sapiens 53-56 16289251-0 2005 Temporal dynamics of dissolved and particulate organic carbon in the northern Adriatic Sea in relation to the mucilage events. Carbon 55-61 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 87-90 24656351-7 2014 The adsorption capacities of prepared ACFs/CNFs in this study were determined to be approximately 191, 39 and 70 mg/g for BSA, GOx and YqeH, respectively, revealing that the carbon micro-nanofibers forming synthesized multi-scale web are efficient materials for the immobilization of protein molecules. Carbon 174-180 hydroxyacid oxidase 1 Homo sapiens 127-130 18976900-1 2009 A novel polyaniline-ionic liquid-carbon nanofiber (PANI-IL-CNF) composite was greenly prepared by in situ one-step electropolymerization of aniline in the presence of IL and CNF for fabrication of amperometric biosensors. Carbon 33-39 NPHS1 adhesion molecule, nephrin Homo sapiens 59-62 18976900-1 2009 A novel polyaniline-ionic liquid-carbon nanofiber (PANI-IL-CNF) composite was greenly prepared by in situ one-step electropolymerization of aniline in the presence of IL and CNF for fabrication of amperometric biosensors. Carbon 33-39 NPHS1 adhesion molecule, nephrin Homo sapiens 167-177 16316259-5 2005 Yamamoto allylation constructed the C-5 chiral carbon in the alpha,beta-unsaturated lactone moiety. Carbon 47-53 complement C5 Homo sapiens 36-39 19829755-5 2009 The sensitivity of the sensor was improved by the co-existence of Gox and AuNP on the carbon nanotube. Carbon 86-92 hydroxyacid oxidase 1 Homo sapiens 66-69 19217861-7 2009 The C=C stretching mode frequency was modulated by a coupled torsion around the C13=C14 bond, leading to the photoisomerization around the bond. Carbon 4-5 homeobox C13 Homo sapiens 80-87 24585188-1 2014 KEY MESSAGE: Arabidopsis Ca (2+) -ATPase ACA8 plays a role in sucrose signalling during early seedling development by integrating developmental signals with carbon source availability. Carbon 157-163 autoinhibited Ca2+ -ATPase Arabidopsis thaliana 41-45 24562190-4 2014 As a result, carbon dots can promote photosynthesis by modulating the electron transfer process as they are capable of fastening the conversion of light energy to the electrical energy and finally to the chemical energy as assimilatory power (ATP and NADPH). Carbon 13-19 2,4-dienoyl-CoA reductase 1 Homo sapiens 251-256 24584481-5 2014 Our calculations together with a spin-dependent tight binding model ascribe the diffuse nature of the pi-bands to the multiple spin-split bands originated from the spin-injected carbon atoms residing only in the lower graphene layer. Carbon 178-184 spindlin 1 Homo sapiens 33-37 24584481-5 2014 Our calculations together with a spin-dependent tight binding model ascribe the diffuse nature of the pi-bands to the multiple spin-split bands originated from the spin-injected carbon atoms residing only in the lower graphene layer. Carbon 178-184 spindlin 1 Homo sapiens 127-131 24584481-5 2014 Our calculations together with a spin-dependent tight binding model ascribe the diffuse nature of the pi-bands to the multiple spin-split bands originated from the spin-injected carbon atoms residing only in the lower graphene layer. Carbon 178-184 spindlin 1 Homo sapiens 127-131 19217861-7 2009 The C=C stretching mode frequency was modulated by a coupled torsion around the C13=C14 bond, leading to the photoisomerization around the bond. Carbon 6-7 homeobox C13 Homo sapiens 80-87 16332809-5 2005 Improvement of flavone biosynthesis was achieved by overexpressing the yeast P450 reductase CPR1 in the FSII-expressing recombinant strain and by using acetate rather than glucose or raffinose as the carbon source. Carbon 200-206 peptidylprolyl isomerase CPR1 Saccharomyces cerevisiae S288C 92-96 19035462-2 2009 Glycine N-methyltransferase (GNMT) participates in one-carbon metabolism and affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine. Carbon 55-61 glycine N-methyltransferase Mus musculus 0-27 19035462-2 2009 Glycine N-methyltransferase (GNMT) participates in one-carbon metabolism and affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine. Carbon 55-61 glycine N-methyltransferase Mus musculus 29-33 19056732-4 2009 Here we show that the yeast Mediator subunit Gal11p/MED15 and its activator-targeted KIX domain plays a critical role in fatty acid-dependent transcriptional regulation of fatty acid beta-oxidation and peroxisomal genes by Oaf1p and for the ability of yeast to utilize fatty acids as a sole carbon source. Carbon 291-297 Gal11p Saccharomyces cerevisiae S288C 45-51 19056732-4 2009 Here we show that the yeast Mediator subunit Gal11p/MED15 and its activator-targeted KIX domain plays a critical role in fatty acid-dependent transcriptional regulation of fatty acid beta-oxidation and peroxisomal genes by Oaf1p and for the ability of yeast to utilize fatty acids as a sole carbon source. Carbon 291-297 Gal11p Saccharomyces cerevisiae S288C 52-57 16294029-0 2005 Subcellular localization of the cyclin dependent kinase inhibitor Sic1 is modulated by the carbon source in budding yeast. Carbon 91-97 proliferating cell nuclear antigen Homo sapiens 32-38 24596031-2 2014 The production of biodiesel, in particular, involves the process of upgrading biomass-derived small molecules to diesel precursors containing a specific carbon range (C11 -C23). Carbon 153-159 RNA polymerase III subunit K Homo sapiens 167-170 18608782-6 2009 The ADA inhibitor was deduced as a 2-N-methyl-2,4-diazacycloheptanone by analyses of UV, IR, EI-MASS, (1)H-NMR, (13)C-(1)H NMR, and (13)C-NMR spectroscopy, and was designated IADA-7. Carbon 116-117 adenosine deaminase Homo sapiens 4-7 16294029-0 2005 Subcellular localization of the cyclin dependent kinase inhibitor Sic1 is modulated by the carbon source in budding yeast. Carbon 91-97 cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1 Saccharomyces cerevisiae S288C 66-70 18608782-6 2009 The ADA inhibitor was deduced as a 2-N-methyl-2,4-diazacycloheptanone by analyses of UV, IR, EI-MASS, (1)H-NMR, (13)C-(1)H NMR, and (13)C-NMR spectroscopy, and was designated IADA-7. Carbon 136-137 adenosine deaminase Homo sapiens 4-7 24651211-3 2014 Here, we report an in-situ low-temperature scanning tunneling microscopy (LT-STM) study of the elementary process of chemical vapor deposition (CVD) graphene growth via thermal decomposition of methane on Cu(110), including the formation of monodispersed carbon clusters at the initial stage, the graphene nucleation and the ripening of graphene islands to form continuous graphene film. Carbon 255-261 sulfotransferase family 1A member 3 Homo sapiens 77-80 24651211-4 2014 STM measurement, supported by DFT calculations, suggests that the carbon clusters on the surface are C2H5. Carbon 66-72 sulfotransferase family 1A member 3 Homo sapiens 0-3 16294029-3 2005 We recently showed that Sic1 is involved in carbon source modulation of the critical cell size required to enter S phase. Carbon 44-50 cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1 Saccharomyces cerevisiae S288C 24-28 16294029-4 2005 Here we show that the amount and sub-cellular localization of Sic1 are also carbon source-modulated. Carbon 76-82 cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1 Saccharomyces cerevisiae S288C 62-66 19235764-4 2009 The earlier studies further showed that rsf1 cells exhibit a growth defect on medium containing glycerol, but not ethanol, as sole carbon source. Carbon 131-137 Rsf1p Saccharomyces cerevisiae S288C 40-44 16294029-5 2005 We identify a bipartite nuclear localization sequence responsible for nuclear localization of Sic1 and for correct cell cycle progression in a carbon-source dependent manner. Carbon 143-149 cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1 Saccharomyces cerevisiae S288C 94-98 19235764-5 2009 Importantly, transcriptome profiling of the rsf1 mutant during shift from glucose- to glycerol-based medium revealed that the product of this gene plays a major role in both orchestration of the transition to, and maintenance of, efficient growth on glycerol as sole carbon source. Carbon 267-273 Rsf1p Saccharomyces cerevisiae S288C 44-48 19235764-6 2009 An increase in transcript levels from genes encoding products that function in the stress response, and an imbalance between expression of genes encoding glycerol anabolic and catabolic enzymes, was observed in the rsf1 mutant during steady-state growth on glycerol- but not ethanol-based medium; this suggests the presence of partially separate transcriptional regulatory systems for transition to respiratory growth on each of these two carbon sources. Carbon 439-445 Rsf1p Saccharomyces cerevisiae S288C 215-219 24552471-4 2014 Compounds 5 and 6 possess a unique 7/7 fused carbocyclic core with an internal ester bridge between C-9 and C-14, and 5 exhibited protective activity against H2O2-induced oxidative damage on Caco-2 cells. Carbon 0-1 complement C9 Homo sapiens 100-103 16339936-10 2005 Moreover, the DeltaLIP1 mutants exhibited growth deficiency on both liquid and solid minimal media supplemented with the saturated triglyceride tristearin as the sole carbon source, suggesting that LIP1 is required for utilization of this substance. Carbon 167-173 sphingosine N-acyltransferase subunit LIP1 Saccharomyces cerevisiae S288C 19-23 24603560-6 2014 They also included linkages not directly related to metabolic enzymes, such as those for five central carbon metabolites to ira2, a Ras/PKA pathway regulator, and for the metabolites, S-adenosyl-methionine and S-adenosyl-homocysteine to slt2, a MAP kinase involved in cell wall integrity. Carbon 102-108 Ras GTPase activating protein IRA2 Saccharomyces cerevisiae S288C 124-128 19035765-4 2009 After a two-step desulfinylation process, this reaction provides a procedure for synthesizing diastereomerically pure syn-1,2-sulfanyl amines containing a chiral quaternary carbon adjacent to nitrogen. Carbon 173-179 synapsin I Homo sapiens 118-123 17292104-3 2005 Our recent study demonstrated that aspiration of single-walled carbon nanotubes elicited an unusual inflammatory response in the lungs of exposed mice with a very early switch from the acute inflammatory phase to fibrogenic events resulting in pulmonary deposition of collagen and elastin. Carbon 63-69 elastin Mus musculus 281-288 19146659-9 2009 Furthermore, CRP regulons in different cyanobacterial species/ecotypes are also highly diversified, ranging from photosynthesis, carbon fixation and nitrogen assimilation, to chemotaxis and signal transduction. Carbon 129-135 catabolite gene activator protein Escherichia coli 13-16 24407677-1 2014 Template-free porous carbon nanofibers embedded by vanadium oxide and decorated with iron nanoparticles (Fe@V-CNF) were prepared in a time and cost-saving manner by combining electrospinning and heat treatment processes. Carbon 21-27 NPHS1 adhesion molecule, nephrin Homo sapiens 108-113 24486205-2 2014 We recently developed non-secosteroidal VDR agonists bearing a p-carborane cage (a carbon-containing boron cluster) as a hydrophobic core structure. Carbon 83-89 vitamin D receptor Homo sapiens 40-43 18983889-6 2009 In conclusion, the MTHFR C677T variant is unlikely to play a major role in the susceptibility to bipolar disorder, although MTHFR plays an important role in the one-carbon metabolism and DNA methylation. Carbon 165-171 methylenetetrahydrofolate reductase Homo sapiens 124-129 16311326-4 2005 Sea-level change has influenced phytoplankton evolution, ocean chemistry, and the loci of carbonate, organic carbon, and siliciclastic sediment burial. Carbon 90-96 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 0-3 16137637-1 2005 Serine hydroxymethyltransferase (SHMT) is a key enzyme in the formation and regulation of the folate one-carbon pool. Carbon 105-111 serine hydroxymethyltransferase 1 Homo sapiens 33-37 15865159-2 2005 The initial steps of the catabolism were investigated in cell-free extracts of the bacterial strain MM 1 able to grow with methyl-triethanol-ammonium as sole source of carbon, energy and nitrogen. Carbon 168-174 plexin B2 Homo sapiens 100-104 20030812-0 2009 MTHFR C677T and postmenopausal breast cancer risk by intakes of one-carbon metabolism nutrients: a nested case-control study. Carbon 68-74 methylenetetrahydrofolate reductase Homo sapiens 0-5 24441981-0 2014 Encapsulate-and-peel: fabricating carbon nanotube CMOS integrated circuits in a flexible ultra-thin plastic film. Carbon 34-40 MOS proto-oncogene, serine/threonine kinase Homo sapiens 50-54 16156605-2 2005 Using carbon-supported rhodium octaethylporphyrin, we have separated the Rh(II) state participating reaction and the Rh(III) state participating reaction with CO. We have clearly demonstrated electrocatalytic CO oxidation by rhodium(III) porphyrin. Carbon 6-12 Rh blood group D antigen Homo sapiens 73-79 24551237-9 2014 Thus, the six-carbon ring structure bound to a carboxylic group seems to be a necessary element for leucine/HMB synergy with other stilbenes and hydroxycinnamic acids to stimulate AMPK/Sirt1 dependent FAO; these effects occur at concentrations that produce no independent effects and are readily achievable via oral administration. Carbon 14-20 protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens 180-184 24551237-9 2014 Thus, the six-carbon ring structure bound to a carboxylic group seems to be a necessary element for leucine/HMB synergy with other stilbenes and hydroxycinnamic acids to stimulate AMPK/Sirt1 dependent FAO; these effects occur at concentrations that produce no independent effects and are readily achievable via oral administration. Carbon 14-20 sirtuin 1 Homo sapiens 185-190 24533714-1 2014 AIM: MTHFR mediates the one carbon metabolism pathway. Carbon 28-34 methylenetetrahydrofolate reductase Homo sapiens 5-10 16078850-1 2005 We report, for the first time, the biological activities of four-carbon-atom bridged classical antifolates on dihydrofolate reductase (DHFR), thymidylate synthase (TS), and folylpolyglutamate synthetase (FPGS) as well as antitumor activity. Carbon 65-71 dihydrofolate reductase Homo sapiens 110-133 24286363-0 2014 Lack of isocitrate lyase in Chlamydomonas leads to changes in carbon metabolism and in the response to oxidative stress under mixotrophic growth. Carbon 62-68 uncharacterized protein Chlamydomonas reinhardtii 8-24 16078850-1 2005 We report, for the first time, the biological activities of four-carbon-atom bridged classical antifolates on dihydrofolate reductase (DHFR), thymidylate synthase (TS), and folylpolyglutamate synthetase (FPGS) as well as antitumor activity. Carbon 65-71 dihydrofolate reductase Homo sapiens 135-139 16078850-1 2005 We report, for the first time, the biological activities of four-carbon-atom bridged classical antifolates on dihydrofolate reductase (DHFR), thymidylate synthase (TS), and folylpolyglutamate synthetase (FPGS) as well as antitumor activity. Carbon 65-71 thymidylate synthetase Homo sapiens 142-162 23955575-3 2014 Stem-like cells SQ20B/SidePopulation(SP)/CD44(+)/ALDH(high) were more resistant to both photon and carbon ion irradiation compared with non-CSCs. Carbon 99-105 CD44 molecule (Indian blood group) Homo sapiens 41-45 16078850-1 2005 We report, for the first time, the biological activities of four-carbon-atom bridged classical antifolates on dihydrofolate reductase (DHFR), thymidylate synthase (TS), and folylpolyglutamate synthetase (FPGS) as well as antitumor activity. Carbon 65-71 folylpolyglutamate synthase Homo sapiens 173-202 23955575-5 2014 SQ20B/SP/CD44(+)/ALDH(high) were capable of an extended G2/M arrest phase in response to photon or carbon ion irradiation compared with non-CSCs. Carbon 99-105 CD44 molecule (Indian blood group) Homo sapiens 9-13 16078850-1 2005 We report, for the first time, the biological activities of four-carbon-atom bridged classical antifolates on dihydrofolate reductase (DHFR), thymidylate synthase (TS), and folylpolyglutamate synthetase (FPGS) as well as antitumor activity. Carbon 65-71 folylpolyglutamate synthase Homo sapiens 204-208 24475979-3 2014 We proposed a hydrogen redox model to clarify the resistive switch mechanism of high/low resistance states (HRS/LRS) in carbon RRAM. Carbon 120-126 leucyl-tRNA synthetase 1 Homo sapiens 112-115 16040659-5 2005 Similar to plants missing ATG7, those missing ATG5 display early senescence and are hypersensitive to either nitrogen or carbon starvation, which is accompanied by a more rapid loss of organellar and cytoplasmic proteins. Carbon 121-127 SAC domain-containing protein 8 Arabidopsis thaliana 46-50 24475979-4 2014 The electrical conduction mechanism of LRS is attributed to conductive sp2 carbon filament with conjugation double bonds by dehydrogenation, while the electrical conduction of HRS resulted from the formation of insulating sp3-type carbon filament through hydrogenation process. Carbon 75-81 leucyl-tRNA synthetase 1 Homo sapiens 39-42 15927466-2 2005 Analogues that incorporated a bulky substituent at the first carbon position of benzylamine or isoquinoline showed over 30-fold selectivity for DPP-IV over both DPP8 and DPP-II. Carbon 61-67 dipeptidyl peptidase 4 Homo sapiens 144-150 24466213-3 2014 Here we show that the cAMP receptor protein (CRP), a well-known carbon utilization regulator, had an inhibitory effect on the expression of Pu promoter in a cAMP-dependent manner. Carbon 64-70 catabolite gene activator protein Escherichia coli 22-43 24466213-3 2014 Here we show that the cAMP receptor protein (CRP), a well-known carbon utilization regulator, had an inhibitory effect on the expression of Pu promoter in a cAMP-dependent manner. Carbon 64-70 catabolite gene activator protein Escherichia coli 45-48 24274759-0 2014 On the direct electron transfer, sensing, and enzyme activity in the glucose oxidase/carbon nanotubes system. Carbon 85-91 hydroxyacid oxidase 1 Homo sapiens 69-84 15927466-2 2005 Analogues that incorporated a bulky substituent at the first carbon position of benzylamine or isoquinoline showed over 30-fold selectivity for DPP-IV over both DPP8 and DPP-II. Carbon 61-67 dipeptidyl peptidase 7 Homo sapiens 170-176 15657716-1 2005 The aim of this work was to examine the role of sucrose-6-phosphate phosphatase (SPP; EC 3.1.3.24) in photosynthetic carbon partitioning. Carbon 117-123 sucrose-phosphatase 1 Nicotiana tabacum 48-79 25338119-4 2014 The tap density, gravimetric and volumetric capacities, and cyclic and rate performance of the TiO2/C composites are effectively improved. Carbon 100-101 nuclear RNA export factor 1 Homo sapiens 4-7 24090870-0 2014 Design of a multiwalled carbon nanotube-Nafion-cysteamine modified tyrosinase biosensor and its adaptation of dopamine determination. Carbon 24-30 tyrosinase Homo sapiens 67-77 24090870-1 2014 In this work, a multiwalled carbon nanotube (MWCNT)-Nafion-cysteamine (CA) modified tyrosinase biosensor brings a new and original perspective to biosensor technology intended for the development of dopamine determination. Carbon 28-34 tyrosinase Homo sapiens 84-94 15657716-1 2005 The aim of this work was to examine the role of sucrose-6-phosphate phosphatase (SPP; EC 3.1.3.24) in photosynthetic carbon partitioning. Carbon 117-123 sucrose-phosphatase 1 Nicotiana tabacum 81-84 15941036-6 2005 Here, the CD2 rocking band data are used to determine the amount of gauche conformers at the deuterated carbon positions C-4 and C-6, and C-12. Carbon 104-110 CD2 molecule Homo sapiens 10-13 15941036-6 2005 Here, the CD2 rocking band data are used to determine the amount of gauche conformers at the deuterated carbon positions C-4 and C-6, and C-12. Carbon 104-110 complement C4A (Rodgers blood group) Homo sapiens 121-124 15941036-6 2005 Here, the CD2 rocking band data are used to determine the amount of gauche conformers at the deuterated carbon positions C-4 and C-6, and C-12. Carbon 10-11 complement C4A (Rodgers blood group) Homo sapiens 121-124 15852111-5 2005 In the presence of PPh3, complexes act as a Michael acceptor to afford the zwitterionic sigma-allenylphosphonium complexes (eta5-MeC5H4)(CO)2MnC(R)=C=C(PPh3)R" (5) resulting from nucleophilic attack by the phosphine on the remote alkynyl carbon atom. Carbon 137-138 protein phosphatase 4 catalytic subunit Homo sapiens 152-156 24220759-4 2014 The product, NADPH, triggers the hydroxylation of p-hydroxybenzoate by HBH in the presence of oxygen to produce 3,4-dihydroxybenzoate, which results in a change in electron concentration at the working carbon electrode, which is detected by the potentiostat. Carbon 202-208 2,4-dienoyl-CoA reductase 1 Homo sapiens 13-18 15806610-4 2005 Here, we analysed the behaviour of a sfp1 null mutant during balanced and transitory states of growth in batch in response to changes in the growth medium carbon sources. Carbon 155-161 zinc-coordinating transcription factor SFP1 Saccharomyces cerevisiae S288C 37-41 24363453-2 2014 We present here a reproducible method to synthesize carbon chains in situ TEM. Carbon 52-58 MFT2 Homo sapiens 74-77 24363453-3 2014 Moreover, we present a direct observation of the bond length alternation in a pure carbon chain by aberration corrected TEM. Carbon 83-89 MFT2 Homo sapiens 120-123 24257509-15 2014 We found significant SNP-by-pollutant interactions for rs7813, rs910925, and rs1062923 in GEMIN4 and black carbon and PM2.5 for miR-1, -126, -146a, -222, and -9, and for rs1640299 in DGCR8 and SO4 for miR-1 and -135a. Carbon 107-113 DGCR8 microprocessor complex subunit Homo sapiens 183-188 15806610-7 2005 The SFP1 gene product is required to sustain the increase of both rRNA and protein content that in wild-type cells takes place in respiro-fermentative growth conditions, while it seems dispensable for growth on non-fermentable carbon sources. Carbon 227-233 zinc-coordinating transcription factor SFP1 Saccharomyces cerevisiae S288C 4-8 15748825-0 2005 The fabrication of a colloidal gold-carbon nanotubes composite film on a gold electrode and its application for the determination of cytochrome c. Carbon 36-42 cytochrome c, somatic Equus caballus 133-145 23559662-0 2014 Differential stimulation of neurotrophin release by the biocompatible nano-material (carbon nanotube) in primary cultured neurons. Carbon 85-91 brain derived neurotrophic factor Homo sapiens 28-40 23559662-7 2014 Although the carbon nanotubes did not change neurotrophin expression levels, it stimulated brain-derived neurotrophic factor release into the media from both types of neurons. Carbon 13-19 brain derived neurotrophic factor Homo sapiens 91-124 31773048-8 2014 We found that N- and C-terminal fragments, encoding multiple motifs including sequences involved in binding integrins and CD44, a domain know to promote adhesion contribute to OPN"s ability to increase HIV replication. Carbon 21-22 CD44 molecule (Indian blood group) Homo sapiens 122-126 15664991-3 2005 The latest novel function to be proposed for myoglobin is a P450 type hydroxylation activity of aromatic carbons (Watanabe, Y., and Ueno, T. (2003) Bull. Carbon 105-112 myoglobin Homo sapiens 45-54 15952298-7 2005 The Al-FL, Al-LC and C-LC groups showed significantly higher percentages of platelets positive for CD62P than the healthy controls. Carbon 15-16 selectin P Homo sapiens 99-104 24157611-3 2014 While the cytoplasmic TPI is involved in the glycolysis, the chloroplastic isoform participates in the Calvin-Benson cycle, a key photosynthetic process responsible for carbon fixation. Carbon 169-175 uncharacterized protein Chlamydomonas reinhardtii 22-25 24295035-5 2013 This local heating effect exhibits a solvent aliphatic chain length dependence for solvents C11 and longer, where solvents with an even number of carbons behave differently than those with an odd number of carbons. Carbon 146-153 aldo-keto reductase family 1 member C4 Homo sapiens 92-95 24295035-5 2013 This local heating effect exhibits a solvent aliphatic chain length dependence for solvents C11 and longer, where solvents with an even number of carbons behave differently than those with an odd number of carbons. Carbon 206-213 aldo-keto reductase family 1 member C4 Homo sapiens 92-95 15722468-1 2005 Plastids of nongreen tissues can import carbon in the form of glucose 6-phosphate via the glucose 6-phosphate/phosphate translocator (GPT). Carbon 40-46 UDP-glcnac-adolichol phosphate glcnac-1-p-transferase Arabidopsis thaliana 90-132 23876540-0 2013 Sensitive ECL immunosensor for detection of retinol-binding protein based on double-assisted signal amplification strategy of multiwalled carbon nanotubes and Ru(bpy)3(2+) doped mesoporous silica nanospheres. Carbon 138-144 retinol binding protein 4 Homo sapiens 44-67 23876540-2 2013 The primary antibody anti-RBP was immobilized onto multiwalled carbon nanotubes (MWCNTs), which have large surface area and high electrical conductivity. Carbon 63-69 retinol binding protein 4 Homo sapiens 26-29 23899460-5 2013 The CB1 receptor antagonist AM251, but not the GABAA receptor antagonist bicuculline, attenuated the effect induced by AEA+c-Ptio combination. Carbon 10-11 cannabinoid receptor 1 Rattus norvegicus 4-7 20030812-11 2009 CONCLUSIONS: This study provides support that the MTHFR 677TT genotype is associated with a moderate increase in risk of postmenopausal breast cancer and that this risk may be attenuated with high intakes of some one-carbon associated nutrients. Carbon 217-223 methylenetetrahydrofolate reductase Homo sapiens 50-55 15722468-1 2005 Plastids of nongreen tissues can import carbon in the form of glucose 6-phosphate via the glucose 6-phosphate/phosphate translocator (GPT). Carbon 40-46 UDP-glcnac-adolichol phosphate glcnac-1-p-transferase Arabidopsis thaliana 134-137 15680604-2 2005 The reactivity towards BCl(3) follows the order: C-4>or=C-2>C-6>C-3 for C-glucopyranosyl derivatives and C-3>or=C-4>C-6>C-2 for C-galactopyranosyl derivatives. Carbon 24-25 complement C4A (Rodgers blood group) Homo sapiens 49-52 15680604-2 2005 The reactivity towards BCl(3) follows the order: C-4>or=C-2>C-6>C-3 for C-glucopyranosyl derivatives and C-3>or=C-4>C-6>C-2 for C-galactopyranosyl derivatives. Carbon 24-25 complement C2 Homo sapiens 59-62 23732860-2 2013 In this work, an innovative strategy is reported to tap the sensitivity potential of current electrochemiluminescence (ECL) biosensing system by dispersedly anchoring the DNA beacons on the gold nanoparticles (GNPs) array which was electrodeposited on the glassy carbon electrode surface, rather than simply sprawling the coil-like strands onto planar gold surface. Carbon 263-269 nuclear RNA export factor 1 Homo sapiens 52-55 23770970-5 2013 After the construction of the immunosensor based on the traditional sandwich protocol with glucose oxidase (GOx) functionalized carbon nanotube (CNT) as detection antibody label, the GOx attached onto electrode surface would catalyze glucose reaction to produce H2O2 and cause the decrease of redox current of the electrode. Carbon 128-134 hydroxyacid oxidase 1 Homo sapiens 91-106 25084402-1 2009 Tyrosinase (TYR, EC 1.14.18.1) was physically adsorbed onto a carbon felt (CF) together with acridine orange (AO). Carbon 62-68 tyrosinase Homo sapiens 0-10 25084402-1 2009 Tyrosinase (TYR, EC 1.14.18.1) was physically adsorbed onto a carbon felt (CF) together with acridine orange (AO). Carbon 62-68 tyrosinase Homo sapiens 12-15 15680604-2 2005 The reactivity towards BCl(3) follows the order: C-4>or=C-2>C-6>C-3 for C-glucopyranosyl derivatives and C-3>or=C-4>C-6>C-2 for C-galactopyranosyl derivatives. Carbon 24-25 complement C4A (Rodgers blood group) Homo sapiens 124-127 15680604-2 2005 The reactivity towards BCl(3) follows the order: C-4>or=C-2>C-6>C-3 for C-glucopyranosyl derivatives and C-3>or=C-4>C-6>C-2 for C-galactopyranosyl derivatives. Carbon 24-25 complement C2 Homo sapiens 138-141 18986671-1 2008 Biodegradable organic carbon (BDOC) from OH radical oxidation (UV-H2O2) of the recalcitrant industrial anti-foaming agents and flame retardants, tri-n-butyl phosphate (TBP) and tris(2-chloroethyl) phosphate (TCEP), was quantified with respect to the fraction of the TBP or TCEP photooxidized. Carbon 22-28 TATA-box binding protein Homo sapiens 168-171 15667329-0 2005 Carbon source induced yeast-to-hypha transition in Candida albicans is dependent on the presence of amino acids and on the G-protein-coupled receptor Gpr1. Carbon 0-6 Gpr1p Saccharomyces cerevisiae S288C 150-154 18986671-1 2008 Biodegradable organic carbon (BDOC) from OH radical oxidation (UV-H2O2) of the recalcitrant industrial anti-foaming agents and flame retardants, tri-n-butyl phosphate (TBP) and tris(2-chloroethyl) phosphate (TCEP), was quantified with respect to the fraction of the TBP or TCEP photooxidized. Carbon 22-28 TATA-box binding protein Homo sapiens 266-269 23770970-5 2013 After the construction of the immunosensor based on the traditional sandwich protocol with glucose oxidase (GOx) functionalized carbon nanotube (CNT) as detection antibody label, the GOx attached onto electrode surface would catalyze glucose reaction to produce H2O2 and cause the decrease of redox current of the electrode. Carbon 128-134 hydroxyacid oxidase 1 Homo sapiens 108-111 23770970-5 2013 After the construction of the immunosensor based on the traditional sandwich protocol with glucose oxidase (GOx) functionalized carbon nanotube (CNT) as detection antibody label, the GOx attached onto electrode surface would catalyze glucose reaction to produce H2O2 and cause the decrease of redox current of the electrode. Carbon 128-134 hydroxyacid oxidase 1 Homo sapiens 183-186 18562192-1 2008 The formation of neodymium hexacyanoferrate (NdHCF) nanoparticles (NPs) on the surface of glucose oxidase/chitosan (GOx/CHIT) modified glass carbon electrode induced by enzymatic reaction was described and characterized. Carbon 141-147 hydroxyacid oxidase 1 Homo sapiens 116-119 15720135-3 2005 Adduct A7 consists of two 1,N2-etheno-2"-deoxyguanosine (1,N2-epsilon dGuo) residues linked to a hydroxy-carbon side chain; adducts A8 and A9 are interconvertible 1,N2-epsilon dGuo derivatives bearing a THF moiety. Carbon 105-111 immunoglobulin kappa variable 2D-24 (non-functional) Homo sapiens 7-9 21581240-5 2008 In the crystal structure, mol-ecules are linked by C-H O hydrogen bonds to generate C(5), C(13) and edge-fused R(3) (3)(28) rings. Carbon 51-52 homeobox C13 Homo sapiens 90-95 24367416-4 2013 Our approach focuses exclusively on transition metal-catalyzed reactions that allow the introduction of -CFH2, -CF2H, -C n F2 n +1 and -SCF3 groups onto sp2 carbon atoms. Carbon 157-163 complement factor H Homo sapiens 105-108 24101362-0 2013 Effects of methionine synthase and methylenetetrahydrofolate reductase gene polymorphisms on markers of one-carbon metabolism. Carbon 108-114 methylenetetrahydrofolate reductase Homo sapiens 35-70 15649071-1 2005 The procedure for the fabrication of a detector termed NACAD, nanofabricated carbon-based detector, is described. Carbon 77-83 NAC alpha domain containing Homo sapiens 55-60 24013633-8 2013 The feaR gene is upregulated by carbon or nitrogen limitation, which we propose reflects regulation of feaR by the cyclic AMP receptor protein (CRP) and the nitrogen assimilation control protein (NAC), respectively. Carbon 32-38 catabolite gene activator protein Escherichia coli 115-142 24013633-8 2013 The feaR gene is upregulated by carbon or nitrogen limitation, which we propose reflects regulation of feaR by the cyclic AMP receptor protein (CRP) and the nitrogen assimilation control protein (NAC), respectively. Carbon 32-38 catabolite gene activator protein Escherichia coli 144-147 18769905-1 2008 AIMS/HYPOTHESIS: Pyruvate carboxylase (PC) or pyruvate dehydrogenase (PDH) is required to transfer carbons from pyruvate into the Krebs cycle. Carbon 99-106 pyruvate carboxylase Rattus norvegicus 17-37 18769905-1 2008 AIMS/HYPOTHESIS: Pyruvate carboxylase (PC) or pyruvate dehydrogenase (PDH) is required to transfer carbons from pyruvate into the Krebs cycle. Carbon 99-106 pyruvate carboxylase Rattus norvegicus 39-41 15568844-3 2004 Here we report cross-linked films of myoglobin (Mb) and poly(L-lysine) (PLL) chemically attached to oxidized carbon cloth cathodes that in microemulsions feature the protein in a water-rich film environment with reactant in an oil-rich environment. Carbon 109-115 myoglobin Homo sapiens 37-46 18574605-3 2008 25-Azalanosterol inhibited the incorporation of [methyl-(3)H(3)] AdoMet into the C-24 of ergosterol in whole cells of C. albicans. Carbon 81-82 methionine adenosyltransferase I, alpha Mus musculus 65-71 24056099-10 2013 Several other AHLs with substituted and unsubstituted acyl chains between 6 and 10 carbons also displayed an AinR-dependent effect on Pqrr-lacZ; however, AHLs with acyl chains of four carbons or 12 or more carbons lacked activity. Carbon 83-90 ainR Vibrio fischeri ES114 109-113 24056099-10 2013 Several other AHLs with substituted and unsubstituted acyl chains between 6 and 10 carbons also displayed an AinR-dependent effect on Pqrr-lacZ; however, AHLs with acyl chains of four carbons or 12 or more carbons lacked activity. Carbon 184-191 ainR Vibrio fischeri ES114 109-113 24056099-10 2013 Several other AHLs with substituted and unsubstituted acyl chains between 6 and 10 carbons also displayed an AinR-dependent effect on Pqrr-lacZ; however, AHLs with acyl chains of four carbons or 12 or more carbons lacked activity. Carbon 184-191 ainR Vibrio fischeri ES114 109-113 15591615-1 2004 The activity of glutamate dehydrogenase (GDH), an important enzyme in carbon and nitrogen metabolism, is routinely assayed by photometry. Carbon 70-76 glutamate dehydrogenase 1 Homo sapiens 16-39 23911868-6 2013 Poly I:C activated NF-kappaB and STAT-1 signaling in a length- and cell-type-dependent fashion. Carbon 7-8 signal transducer and activator of transcription 1 Homo sapiens 33-39 19186800-4 2008 When geosmin and 2-MIB in raw was less than 30 ng/L, activated carbon adsorption should be equipped with enhanced coagulations. Carbon 63-69 MIB E3 ubiquitin protein ligase 1 Homo sapiens 19-22 19186800-5 2008 When thiol and thioether in raw water was more than 20 microg/L, or geosmin and 2-MIB was more than 30 ng/L, ozone-activated carbon process should be added after the conventional water treatment process. Carbon 125-131 MIB E3 ubiquitin protein ligase 1 Homo sapiens 82-85 18645651-2 2008 An amperometric biosensor based on glucose oxidase (GOx) (EC 1.1.3.4) from Penicillum vitale, immobilized on a carbon rod electrode by cross-linking with glutaraldehyde, was exploited as a model system for demonstration of the approach described here. Carbon 111-117 hydroxyacid oxidase 1 Homo sapiens 35-50 18645651-2 2008 An amperometric biosensor based on glucose oxidase (GOx) (EC 1.1.3.4) from Penicillum vitale, immobilized on a carbon rod electrode by cross-linking with glutaraldehyde, was exploited as a model system for demonstration of the approach described here. Carbon 111-117 hydroxyacid oxidase 1 Homo sapiens 52-55 24283018-0 2013 What if we could tap vast deposits of methane-rich brine deep beneath the ocean and use the energy to cut carbon emissions? Carbon 106-112 nuclear RNA export factor 1 Homo sapiens 17-20 15591615-1 2004 The activity of glutamate dehydrogenase (GDH), an important enzyme in carbon and nitrogen metabolism, is routinely assayed by photometry. Carbon 70-76 glutamate dehydrogenase 1 Homo sapiens 41-44 15598787-1 2004 Thymidylate synthase (TS), a key one-carbon metabolizing gene, encodes an enzyme that converts dUMP to dTMP, the rate-limiting nucleotide in DNA synthesis. Carbon 37-43 thymidylate synthetase Homo sapiens 0-20 18594211-1 2008 Cobalamin-dependent methionine synthase, with a cofactor of vitamin B12, catalyzes the reaction of 5-methyltetrahydrofolate and homocysteine to form methionine and tetrahydrofolate, which takes a core position in folate cycle, one-carbon-unit transfer, and sulfur amino acid pathways. Carbon 231-237 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 0-39 15598787-1 2004 Thymidylate synthase (TS), a key one-carbon metabolizing gene, encodes an enzyme that converts dUMP to dTMP, the rate-limiting nucleotide in DNA synthesis. Carbon 37-43 thymidylate synthetase Homo sapiens 22-24 18969709-1 2004 The suitability of colloidal-gold cysteamine-modified carbon paste electrodes (nAu-Cyst-CPE) for the electrochemical determination of sulphur-containing compounds is illustrated in this work by determining the amino acid methionine in real samples, as well as a methionine-based peptide. Carbon 54-60 carboxypeptidase E Homo sapiens 88-91 18407565-6 2008 The C-7, C-8, C-10, C-15 and C-16 residues of Tes, Cor and Adr consistently give rise to singlets or doublets with splittings of less than 0.5 ppm, indicating similar local conformations. Carbon 4-5 placenta associated 8 Homo sapiens 20-24 18344420-1 2008 Sucrose synthase (Sus; EC 2.4.1.13) is a key enzyme of sucrose metabolism in plant cells, providing carbon for respiration and for the synthesis of cell wall polymers and starch. Carbon 100-106 sucrose synthase Nicotiana tabacum 0-16 24454112-1 2013 In the title compound, C27H23N3O2, the geminal benzyl groups branching out from the methine adjacent to the isoxazole group are both syn-oriented to the methyl group of the pyridazinone moiety, as reflected by C-C distances of 3.812 (2) and 4.369 (2) A between the methyl carbon and the nearest ring carbon of each benzyl group. Carbon 23-24 synemin Homo sapiens 133-136 24454112-1 2013 In the title compound, C27H23N3O2, the geminal benzyl groups branching out from the methine adjacent to the isoxazole group are both syn-oriented to the methyl group of the pyridazinone moiety, as reflected by C-C distances of 3.812 (2) and 4.369 (2) A between the methyl carbon and the nearest ring carbon of each benzyl group. Carbon 210-211 synemin Homo sapiens 133-136 24454112-1 2013 In the title compound, C27H23N3O2, the geminal benzyl groups branching out from the methine adjacent to the isoxazole group are both syn-oriented to the methyl group of the pyridazinone moiety, as reflected by C-C distances of 3.812 (2) and 4.369 (2) A between the methyl carbon and the nearest ring carbon of each benzyl group. Carbon 272-278 synemin Homo sapiens 133-136 24454112-1 2013 In the title compound, C27H23N3O2, the geminal benzyl groups branching out from the methine adjacent to the isoxazole group are both syn-oriented to the methyl group of the pyridazinone moiety, as reflected by C-C distances of 3.812 (2) and 4.369 (2) A between the methyl carbon and the nearest ring carbon of each benzyl group. Carbon 300-306 synemin Homo sapiens 133-136 24108357-2 2013 AMPK"s homolog in the yeast Saccharomyces cerevisiae, the SNF1 protein kinase, is a central regulator of carbon metabolism that inhibits the Snf3/Rgt2-Rgt1 glucose sensing pathway and activates genes involved in respiration. Carbon 105-111 Rgt1p Saccharomyces cerevisiae S288C 151-155 18344420-1 2008 Sucrose synthase (Sus; EC 2.4.1.13) is a key enzyme of sucrose metabolism in plant cells, providing carbon for respiration and for the synthesis of cell wall polymers and starch. Carbon 100-106 sucrose synthase Nicotiana tabacum 18-21 15506784-1 2004 The electrical conductances of dithiolates of polyacene (PA(n)DTs) and polyphenanthrene (PPh(n)DTs), which are typical carbon ladder compounds, are calculated by means of the Landauer formulation combined with density functional theory, where n is the number of benzene rings involved. Carbon 119-125 enolase 1 Homo sapiens 89-92 18593150-2 2008 With the aid of pi-pi interactions between the walls of carbon nanotubes (CNTs) and the PPA skeleton together with the ferrocene pendants, the polymer (P 1, P2(5) and P2(10)) chains effectively wrapped round the shells of both single-walled carbon nanotubes (SWNTs) and multiwalled carbon nanotubes (MWNTs). Carbon 241-247 cyclin dependent kinase 5 regulatory subunit 1 Homo sapiens 157-162 18593150-2 2008 With the aid of pi-pi interactions between the walls of carbon nanotubes (CNTs) and the PPA skeleton together with the ferrocene pendants, the polymer (P 1, P2(5) and P2(10)) chains effectively wrapped round the shells of both single-walled carbon nanotubes (SWNTs) and multiwalled carbon nanotubes (MWNTs). Carbon 241-247 cyclin dependent kinase 5 regulatory subunit 1 Homo sapiens 157-162 24075748-5 2013 Circulating LBP was also positively associated with C-IMT (r = 0.27, p < 0.0001). Carbon 0-1 lipopolysaccharide binding protein Homo sapiens 12-15 15483694-0 2004 The reaction of RhCp*(CH3)2(L)(L = pyridine, dmso) with GaCp* and AlCp*: a new type of carbon-carbon bond activation reaction. Carbon 87-93 glutaminase Homo sapiens 56-60 24116805-1 2013 Spin-orbit interaction provides a spin filtering effect in carbon nanotube based Cooper pair splitters that allows us to determine spin correlators directly from current measurements. Carbon 59-65 spindlin 1 Homo sapiens 0-4 24116805-1 2013 Spin-orbit interaction provides a spin filtering effect in carbon nanotube based Cooper pair splitters that allows us to determine spin correlators directly from current measurements. Carbon 59-65 spindlin 1 Homo sapiens 34-38 24116805-1 2013 Spin-orbit interaction provides a spin filtering effect in carbon nanotube based Cooper pair splitters that allows us to determine spin correlators directly from current measurements. Carbon 59-65 spindlin 1 Homo sapiens 131-135 23105766-2 2008 Methylenetetrahydrofolate reductase, the key enzyme involved in one carbon metabolism produces methyl tetrahydrofolate from methylene tetrahydrofolate, which in turn donates methyl group to homocysteine to generate methionine. Carbon 68-74 methylenetetrahydrofolate reductase Homo sapiens 0-35 15483694-0 2004 The reaction of RhCp*(CH3)2(L)(L = pyridine, dmso) with GaCp* and AlCp*: a new type of carbon-carbon bond activation reaction. Carbon 94-100 glutaminase Homo sapiens 56-60 18373623-8 2008 The balance between COX and AOX activity helps regulate plant metabolism by adjusting the demand for ATP to that for reducing power and carbon skeleton intermediates. Carbon 136-142 acyl-CoA oxidase 1 Homo sapiens 28-31 23998190-2 2013 The NMR spectra show that the two delta-dicarbonyl sugars exist as two anomeric alpha- and beta-oxetanosyl forms, derived from the hemiacetalization of the C-3 hydroxyl group with the aldehydic carbon. Carbon 42-48 complement C3 Homo sapiens 156-159 23896051-2 2013 The gene methylenetetrahydrofolate reductase (MTHFR), which encodes for a key enzyme in one carbon metabolism, shows a high prevalence of polymorphism in patients with developmental disorders. Carbon 92-98 methylenetetrahydrofolate reductase Homo sapiens 9-44 23896051-2 2013 The gene methylenetetrahydrofolate reductase (MTHFR), which encodes for a key enzyme in one carbon metabolism, shows a high prevalence of polymorphism in patients with developmental disorders. Carbon 92-98 methylenetetrahydrofolate reductase Homo sapiens 46-51 23898784-4 2013 Specifically, the enzyme, hereafter referred to as WlaRD, catalyzes the N-formylation of dTDP-3,6-dideoxy-3-amino-d-glucose (dTDP-Qui3N) using N(10)-formyltetrahydrofolate as the carbon source. Carbon 179-185 TAR DNA-binding protein-43 homolog Drosophila melanogaster 89-93 23898784-4 2013 Specifically, the enzyme, hereafter referred to as WlaRD, catalyzes the N-formylation of dTDP-3,6-dideoxy-3-amino-d-glucose (dTDP-Qui3N) using N(10)-formyltetrahydrofolate as the carbon source. Carbon 179-185 TAR DNA-binding protein-43 homolog Drosophila melanogaster 125-129 23763276-7 2013 Hyperaccumulation of T6P in the tps2 mutant caused an increase in cytosolic pH and strongly reduced growth rates on non-fermentable carbon sources, emphasizing the crucial role of the trehalose pathway in the regulation of respiratory and fermentative metabolism. Carbon 132-138 trehalose-phosphatase TPS2 Saccharomyces cerevisiae S288C 32-36 23995452-2 2013 Enzymatic assays with purified inducible NOS have shown that the non-radioactive surrogates with 3-(Re1; Ki=84 muM) or 6-carbon linkers (Re2; Ki=6 muM) are stronger inhibitors than the respective metal-free conjugates L1 (Ki=178 muM) and L2 (Ki=36 muM), with Re2 displaying the highest inhibitory potency. Carbon 121-127 G protein-coupled receptor 161 Homo sapiens 137-140 23995452-2 2013 Enzymatic assays with purified inducible NOS have shown that the non-radioactive surrogates with 3-(Re1; Ki=84 muM) or 6-carbon linkers (Re2; Ki=6 muM) are stronger inhibitors than the respective metal-free conjugates L1 (Ki=178 muM) and L2 (Ki=36 muM), with Re2 displaying the highest inhibitory potency. Carbon 121-127 G protein-coupled receptor 161 Homo sapiens 259-262 22686327-0 2013 IL-33 mediates multi-walled carbon nanotube (MWCNT)-induced airway hyper-reactivity via the mobilization of innate helper cells in the lung. Carbon 28-34 interleukin 33 Mus musculus 0-5 22686327-5 2013 In this study, we tested the hypothesis that instillation of multi-walled carbon nanotubes (MWCNT) impair pulmonary function in C57Bl/6 mice due to the development of IL-33-dependent Th2-associated inflammation. Carbon 74-80 interleukin 33 Mus musculus 167-172 23525885-7 2013 The pEG1 gene expression system is an effective tool for the production of heterologous proteins under glucose-limiting conditions, including medium containing glycerol as a carbon source. Carbon 174-180 mesoderm specific transcript Homo sapiens 4-8 23739688-1 2013 The paralogous and functionally redundant GATA transcription factors GNC (for GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM INVOLVED) and GNL/CGA1 (for GNC-LIKE/CYTOKININ-RESPONSIVE GATA FACTOR1) from Arabidopsis (Arabidopsis thaliana) promote greening and repress flowering downstream from the phytohormone gibberellin. Carbon 103-109 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 42-46 23868209-7 2013 Based on the MS and (13)C-NMR data of the products from degradation of [[(13)C3,(15)N]Cys(1)]OT, we postulate that the ultimate degradation products of OT are dimers composed of two pyruvoylated octapeptides held together by one disulfide bridge between the two Cys(6) residues and by one more, non-reducible, linkage resulting from an aldol-type condensation between the two N-terminal pyruvoyl groups. Carbon 24-25 oxytocin/neurophysin I prepropeptide Homo sapiens 93-95 23868209-7 2013 Based on the MS and (13)C-NMR data of the products from degradation of [[(13)C3,(15)N]Cys(1)]OT, we postulate that the ultimate degradation products of OT are dimers composed of two pyruvoylated octapeptides held together by one disulfide bridge between the two Cys(6) residues and by one more, non-reducible, linkage resulting from an aldol-type condensation between the two N-terminal pyruvoyl groups. Carbon 24-25 oxytocin/neurophysin I prepropeptide Homo sapiens 152-154 23348232-6 2013 RESULTS: Intranasal treatment of poly(I:C) significantly induced airway neutrophilia; production of CXCL1, IFN-beta, and CXCL10; and necrotic cell accumulation in BALF. Carbon 40-41 interferon beta 1, fibroblast Mus musculus 107-115 23644525-2 2013 Owing to their exceptionally long spin lifetimes, these carbon-based materials could also have an important impact on spintronics, where carrier spins play a key role in transmitting, processing and storing information. Carbon 56-62 spindlin 1 Homo sapiens 34-38 23810032-5 2013 The Sn inside the CNF is completely covered by the carbon wall. Carbon 51-57 NPHS1 adhesion molecule, nephrin Homo sapiens 18-21 18442968-5 2008 Mutants lacking Guf1 show cold- and heat-sensitive growth defects on non-fermentable carbon sources that are especially pronounced under nutrient-limiting conditions. Carbon 85-91 GTPase GUF1 Saccharomyces cerevisiae S288C 16-20 18445601-3 2008 Under repressive conditions on nonfermentable carbon sources, Maf1 is dephosphorylated and located predominantly in the nucleus. Carbon 46-52 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 62-66 18446757-5 2008 This indicated a shift from grass (C(4))- to tree (C(3))-derived carbon in the woodland, which was also supported by the two-phase (13)C enrichment with depth, i.e. C(3) vegetation dominated the top soil (0-10 cm), but the C(4) contribution increased with depth (more gradual). Carbon 65-71 complement C3 Homo sapiens 51-55 18446757-5 2008 This indicated a shift from grass (C(4))- to tree (C(3))-derived carbon in the woodland, which was also supported by the two-phase (13)C enrichment with depth, i.e. C(3) vegetation dominated the top soil (0-10 cm), but the C(4) contribution increased with depth (more gradual). Carbon 65-71 complement C3 Homo sapiens 165-169 18451149-9 2008 Our studies provide for the first time a link between MDM2, an oncogene with a critical ubiquitin ligase activity and a vital one-carbon donor pathway involved in epigenetic regulation, and DNA metabolism, which has wide ranging implications for both cell biology and tumor development. Carbon 130-136 MDM2 proto-oncogene Homo sapiens 54-58 17669408-9 2008 Treatment of FTEC with TLR3 agonist poly(I:C) resulted in increased expression of interleukin-8, tumor-necrosis factor alpha, human beta-defensin 2, interferon beta, and interferon stimulated genes myxovirus resistance gene 1, 2",5"-oligoadenylate synthetase, and protein kinase R. Additionally, FTEC exposed to poly(I:C) also resulted in the induction of TLR2, TLR3, and TLR7. Carbon 16-17 defensin beta 4B Homo sapiens 132-147 18427121-8 2008 The qualitatively different hydration of the beta-lactoglobulin pore and carbon nanotubes is caused by subtle differences in water-wall interactions and water entropy. Carbon 73-79 beta-lactoglobulin Bos taurus 45-63 18358866-0 2008 Phenol biosensor based on Sonogel-Carbon transducer with tyrosinase alumina sol-gel immobilization. Carbon 34-40 tyrosinase Homo sapiens 57-67 18358866-1 2008 A new biosensor for detection of phenols, based on tyrosinase immobilization with alumina sol-gel on Sonogel-Carbon transducer, has been developed. Carbon 109-115 tyrosinase Homo sapiens 51-61 18358868-5 2008 Membrane bound enzyme exhibited consistent activity in the temperature range 20-45 degrees C. Shelf life of immobilized tyrosinase system was found to be more than 6 months when stored in phosphate buffer at 4 degrees C. An electrochemical biosensor for dopamine was developed by mounting the tyrosinase immobilized eggshell membrane on the surface of glassy carbon electrode. Carbon 359-365 tyrosinase Homo sapiens 120-130 18313306-2 2008 The two stereocenters present in this compound provide an opportunity to examine the enantioselectivity and diastereoselectivity of the MAO-B-catalyzed ring alpha-carbon oxidation of cyclic tertiary amines to give the corresponding conjugated iminiumyl metabolites. Carbon 163-169 monoamine oxidase B Homo sapiens 136-141 18505017-0 2008 Carbon nanotube-based electrochemical sensor for assay of salivary cholinesterase enzyme activity: an exposure biomarker of organophosphate pesticides and nerve agents. Carbon 0-6 butyrylcholinesterase Rattus norvegicus 67-81 18371821-2 2008 Glucose oxidase (GOx) was immobilized in the resulting Pt nanoparticles/mesoporous carbon (Pt/CMK-3) matrix, and then the mixture was cast on a glassy carbon electrode (GCE) using gelatin as a binder. Carbon 83-89 hydroxyacid oxidase 1 Homo sapiens 0-15 18371821-2 2008 Glucose oxidase (GOx) was immobilized in the resulting Pt nanoparticles/mesoporous carbon (Pt/CMK-3) matrix, and then the mixture was cast on a glassy carbon electrode (GCE) using gelatin as a binder. Carbon 83-89 hydroxyacid oxidase 1 Homo sapiens 17-20 18371821-2 2008 Glucose oxidase (GOx) was immobilized in the resulting Pt nanoparticles/mesoporous carbon (Pt/CMK-3) matrix, and then the mixture was cast on a glassy carbon electrode (GCE) using gelatin as a binder. Carbon 151-157 hydroxyacid oxidase 1 Homo sapiens 0-15 18371821-2 2008 Glucose oxidase (GOx) was immobilized in the resulting Pt nanoparticles/mesoporous carbon (Pt/CMK-3) matrix, and then the mixture was cast on a glassy carbon electrode (GCE) using gelatin as a binder. Carbon 151-157 hydroxyacid oxidase 1 Homo sapiens 17-20 17891379-2 2008 Given that oxidatively damaged proteins are generally degraded rather than repaired, we anticipated that Lon deficient cells would exhibit decreased viability during aerobic, but not anaerobic, carbon starvation. Carbon 194-200 putative ATP-dependent Lon protease Escherichia coli 105-108 18053312-2 2008 Efficient one-carbon metabolism requires other B vitamins and the optimal activity of enzymes including 5,10-methylenetetrahydrofolate reductase (MTHFR). Carbon 14-20 methylenetetrahydrofolate reductase Homo sapiens 104-144 18053312-2 2008 Efficient one-carbon metabolism requires other B vitamins and the optimal activity of enzymes including 5,10-methylenetetrahydrofolate reductase (MTHFR). Carbon 14-20 methylenetetrahydrofolate reductase Homo sapiens 146-151 17924136-8 2008 From these and other data we conclude that Tdy1 and Sxd1 function independently to promote carbon export from leaves. Carbon 91-97 predicted GPI-anchored protein 58 Zea mays 43-47 17905578-0 2008 A novel glucose biosensor based on immobilization of glucose oxidase into multiwall carbon nanotubes-polyelectrolyte-loaded electrospun nanofibrous membrane. Carbon 84-90 hydroxyacid oxidase 1 Homo sapiens 53-68 18167546-0 2008 The OSU1/QUA2/TSD2-encoded putative methyltransferase is a critical modulator of carbon and nitrogen nutrient balance response in Arabidopsis. Carbon 81-87 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Arabidopsis thaliana 4-8 18167546-0 2008 The OSU1/QUA2/TSD2-encoded putative methyltransferase is a critical modulator of carbon and nitrogen nutrient balance response in Arabidopsis. Carbon 81-87 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Arabidopsis thaliana 9-13 18167546-0 2008 The OSU1/QUA2/TSD2-encoded putative methyltransferase is a critical modulator of carbon and nitrogen nutrient balance response in Arabidopsis. Carbon 81-87 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Arabidopsis thaliana 14-18 18181979-2 2008 Recent human and animal studies emphasized alterations caused by 13-CRA administration on folate-dependent, one-carbon metabolism. Carbon 112-118 myotubularin related protein 11 Homo sapiens 68-71 18338283-5 2008 To this end, the evaporation and skin penetration of C-14 labeled hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,6-dinitrotoluene (26DNT), and 2,4,6-trinitrotoluene (TNT) were determined from two soil types, Yolo, having 1.2% carbon, and Tinker, having 9.5% carbon. Carbon 53-54 radixin Homo sapiens 107-110 18371655-4 2007 The response efficiencies of the GC and Au electrodes modified with CNF and CMP, using dimethylformamide (DMF) as dispersing agent are significantly different due to the peculiar physical and chemical characteristics of each doping material. Carbon 33-35 NPHS1 adhesion molecule, nephrin Homo sapiens 68-71 17712558-2 2007 Methylenetetrahydrofolate reductase (MTHFR) balances the pool of folate coenzymes in one carbon metabolism of deoxyribonucleic acid (DNA) synthesis and methylation; both are implicated in carcinogenesis of many types of cancer including lymphoma. Carbon 89-95 methylenetetrahydrofolate reductase Homo sapiens 0-35 17712558-2 2007 Methylenetetrahydrofolate reductase (MTHFR) balances the pool of folate coenzymes in one carbon metabolism of deoxyribonucleic acid (DNA) synthesis and methylation; both are implicated in carcinogenesis of many types of cancer including lymphoma. Carbon 89-95 methylenetetrahydrofolate reductase Homo sapiens 37-42 17891500-10 2007 In conclusion, the results of this study suggest that genetic polymorphisms of one-carbon metabolism genes such as MTHFR and TYMS may influence susceptibility to NHL. Carbon 83-89 methylenetetrahydrofolate reductase Homo sapiens 115-120 17927250-3 2007 The influence of the CF2 group, which is located in the alpha-position relative to the carbon bearing the amino group, on the efficiency of the RCM reaction is noteworthy. Carbon 87-93 ATPase H+ transporting accessory protein 1 Homo sapiens 21-24 17956236-4 2007 In both cases, HACL1 catalyses the cleavage step, which involves the splitting of a carbon-carbon bond between the first and second carbon atom in a 2-hydroxyacyl-CoA intermediate leading to the production of an (n-1) aldehyde and formyl-CoA. Carbon 84-90 2-hydroxyacyl-CoA lyase 1 Homo sapiens 15-20 17956236-4 2007 In both cases, HACL1 catalyses the cleavage step, which involves the splitting of a carbon-carbon bond between the first and second carbon atom in a 2-hydroxyacyl-CoA intermediate leading to the production of an (n-1) aldehyde and formyl-CoA. Carbon 91-97 2-hydroxyacyl-CoA lyase 1 Homo sapiens 15-20 17956236-4 2007 In both cases, HACL1 catalyses the cleavage step, which involves the splitting of a carbon-carbon bond between the first and second carbon atom in a 2-hydroxyacyl-CoA intermediate leading to the production of an (n-1) aldehyde and formyl-CoA. Carbon 91-97 2-hydroxyacyl-CoA lyase 1 Homo sapiens 15-20 17937387-5 2007 A real-time polymerase chain reaction analysis of 10 genes in the one-carbon metabolism pathway revealed that 5,10-methylenetetrahydrofolate reductase, S-adenosylhomocysteine hydrolase (Ahcy), and formiminotransferase cyclodeaminase (Ftcd) were significantly down-regulated in Gnmt-/- mice. Carbon 70-76 glycine N-methyltransferase Mus musculus 277-281 19073120-2 2007 Bromhexine in methanol/0.1molL(-1) Britton-Robinson buffer solution (2.5/97.5) shows an anodic response on glassy carbon electrode between pH 2 and 7.5. Carbon 114-120 polyhomeotic homolog 2 Homo sapiens 139-143 17678866-0 2007 A novel glucose biosensor based on immobilization of glucose oxidase in chitosan on a glassy carbon electrode modified with gold-platinum alloy nanoparticles/multiwall carbon nanotubes. Carbon 93-99 hydroxyacid oxidase 1 Homo sapiens 53-68 17678866-1 2007 A novel glucose biosensor was constructed, based on the immobilization of glucose oxidase (GOx) with cross-linking in the matrix of biopolymer chitosan (CS) on a glassy carbon electrode (GCE), which was modified with gold-platinum alloy nanoparticles (Au-PtNPs) by electrodeposition on multiwall carbon nanotubes (CNTs) in CS film (CNTs/CS). Carbon 169-175 hydroxyacid oxidase 1 Homo sapiens 74-89 17678866-1 2007 A novel glucose biosensor was constructed, based on the immobilization of glucose oxidase (GOx) with cross-linking in the matrix of biopolymer chitosan (CS) on a glassy carbon electrode (GCE), which was modified with gold-platinum alloy nanoparticles (Au-PtNPs) by electrodeposition on multiwall carbon nanotubes (CNTs) in CS film (CNTs/CS). Carbon 169-175 hydroxyacid oxidase 1 Homo sapiens 91-94 17678866-1 2007 A novel glucose biosensor was constructed, based on the immobilization of glucose oxidase (GOx) with cross-linking in the matrix of biopolymer chitosan (CS) on a glassy carbon electrode (GCE), which was modified with gold-platinum alloy nanoparticles (Au-PtNPs) by electrodeposition on multiwall carbon nanotubes (CNTs) in CS film (CNTs/CS). Carbon 296-302 hydroxyacid oxidase 1 Homo sapiens 74-89 17678866-1 2007 A novel glucose biosensor was constructed, based on the immobilization of glucose oxidase (GOx) with cross-linking in the matrix of biopolymer chitosan (CS) on a glassy carbon electrode (GCE), which was modified with gold-platinum alloy nanoparticles (Au-PtNPs) by electrodeposition on multiwall carbon nanotubes (CNTs) in CS film (CNTs/CS). Carbon 296-302 hydroxyacid oxidase 1 Homo sapiens 91-94 17596206-2 2007 Functional polymorphisms in genes encoding one-carbon metabolism enzymes, such as methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), methionine synthase (MTR A2756G), methionine synthase reductase (MTRR A66G) and thymidylate synthase (TS), influence folate metabolism and thus might impact on HNSCC risk. Carbon 47-53 methylenetetrahydrofolate reductase Homo sapiens 82-117 17596206-2 2007 Functional polymorphisms in genes encoding one-carbon metabolism enzymes, such as methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), methionine synthase (MTR A2756G), methionine synthase reductase (MTRR A66G) and thymidylate synthase (TS), influence folate metabolism and thus might impact on HNSCC risk. Carbon 47-53 methylenetetrahydrofolate reductase Homo sapiens 119-124 17596206-2 2007 Functional polymorphisms in genes encoding one-carbon metabolism enzymes, such as methylenetetrahydrofolate reductase (MTHFR C677T and A1298C), methionine synthase (MTR A2756G), methionine synthase reductase (MTRR A66G) and thymidylate synthase (TS), influence folate metabolism and thus might impact on HNSCC risk. Carbon 47-53 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 144-163 17990529-11 2007 The potential changes in carbon cycling characteristics were also predicted under assumed climate change scenarios of A1B and A1FI. Carbon 25-31 alpha-1-B glycoprotein Homo sapiens 118-121 15297456-7 2004 Whereas UNG expression is significantly higher in proliferating as compared with nonproliferating cells, such as neurons, the levels of UNG mRNA were increased in brains of cystathionine beta-synthase knockout mice, a model for hyperhomocysteinemia, suggesting that one-carbon metabolism impairment and uracil misincorporation can induce the up-regulation of UNG expression. Carbon 270-276 cystathionine beta-synthase Mus musculus 173-200 23804093-2 2013 Here we present a small-molecule (TTK21) activator of the histone acetyltransferases CBP/p300, which, when conjugated to glucose-based carbon nanosphere (CSP), passed the blood-brain barrier, induced no toxicity, and reached different parts of the brain. Carbon 135-141 CREB binding protein Mus musculus 85-88 23804093-2 2013 Here we present a small-molecule (TTK21) activator of the histone acetyltransferases CBP/p300, which, when conjugated to glucose-based carbon nanosphere (CSP), passed the blood-brain barrier, induced no toxicity, and reached different parts of the brain. Carbon 135-141 E1A binding protein p300 Mus musculus 89-93 15297453-10 2004 In the 5-phenylheme-hHO-1 structure, the phenyl-substituted heme occupies the same position as heme in the heme-HO-1 complex but the 5-phenyl substituent disrupts the rigid hydrophobic wall of residues Met34, Phe214, and residues 26-42 near the alpha-meso carbon. Carbon 256-262 heme oxygenase 1 Homo sapiens 20-25 28809272-3 2013 A 7 mbar growth atmosphere combined with a 25 W plasma permitted the concurrent growth and alignment of carbon nanotubes with electric fields of the order of 0.04 V mum-1 with linear packing densities of up to ~5 x 104 cm-1. Carbon 104-110 PWWP domain containing 3A, DNA repair factor Homo sapiens 165-170 17628085-7 2007 In particular, atomic-scale STM imaging suggested a change from a defected, but essentially graphitic, surface in the first regime to an amorphous carbon surface in the second regime. Carbon 147-153 sulfotransferase family 1A member 3 Homo sapiens 28-31 15297453-10 2004 In the 5-phenylheme-hHO-1 structure, the phenyl-substituted heme occupies the same position as heme in the heme-HO-1 complex but the 5-phenyl substituent disrupts the rigid hydrophobic wall of residues Met34, Phe214, and residues 26-42 near the alpha-meso carbon. Carbon 256-262 heme oxygenase 1 Homo sapiens 21-25 15544474-13 2004 Structural requirements at the C-2 carbon of the 5-substituent of pyrimidine nucleosides have been well established for anti-herpes activity. Carbon 35-41 complement C2 Homo sapiens 31-34 23742482-1 2013 Spin-orbit (de-)excitation of C(+)((2)P) by collisions with H2, a key process for astrochemistry, is investigated. Carbon 30-34 spindlin 1 Homo sapiens 0-4 15282205-6 2004 MtF expression rescued the respiratory deficiency caused by the loss of frataxin protecting the activity of iron-sulfur enzymes and enabling frataxin-deficient cells to grow on non-fermentable carbon sources. Carbon 193-199 ferritin mitochondrial Homo sapiens 0-3 23624507-10 2013 Parg(-/-) cells were more sensitive to LET 70 keV/mum carbon-ion irradiation than Parp-1(-/-) cells. Carbon 54-60 poly (ADP-ribose) glycohydrolase Mus musculus 0-4 17565971-13 2007 CONCLUSIONS: Based on the results obtained it is proposed that mechanisms producing carbon assimilates or importing sucrose could be affected in elo1 plants and could account for the observed differences, implying a role for Elongator in the regulation of these processes. Carbon 84-90 Paxneb protein-like protein Arabidopsis thaliana 145-149 17690467-1 2007 Bacterial glycerophosphodiester phosphodiesterases (GP-PDEs), GlpQ and UgpQ, are well-characterized periplasmic and cytosolic proteins that play critical roles in the hydrolysis of deacylated glycerophospholipids to glycerol phosphate and alcohol, which are utilized as major sources of carbon and phosphate. Carbon 287-293 glycerophosphodiester phosphodiesterase domain containing 4 Homo sapiens 71-75 15349172-2 2004 When hydrogen is bubbled through 1,2-dichloroethane solutions of 1 or 2, two new species were formed in each case by C-Cl bond activation of the solvent, Ir(H)2Cl(eta1-N-L)(PPh3)2 (L = py, 4; iQ, 5) and IrH(Cl)2(eta1-N-L)(PPh3)2 (L = py, 6; iQ, 7). Carbon 117-118 secreted phosphoprotein 1 Homo sapiens 163-167 18048020-4 2007 CNTO2424 down-regulates poly(I:C)-induced production of IL-6, IL-8, MCP-1, RANTES, and IP-10 in human lung epithelial cells. Carbon 0-1 C-C motif chemokine ligand 5 Homo sapiens 75-81 18048020-4 2007 CNTO2424 down-regulates poly(I:C)-induced production of IL-6, IL-8, MCP-1, RANTES, and IP-10 in human lung epithelial cells. Carbon 0-1 C-X-C motif chemokine ligand 10 Homo sapiens 87-92 17580895-2 2007 The stereoelectronic properties of the substituents at the C-3 position and their interactions with the incoming carbon nucleophiles control the diastereoselectivity of addition at the C-5 position, favoring the formation of l-ido derivatives as major products in most of the cases studied. Carbon 113-119 complement C3 Homo sapiens 59-62 17587728-0 2007 Nano-sized carbon black exposure exacerbates atherosclerosis in LDL-receptor knockout mice. Carbon 11-17 low density lipoprotein receptor Mus musculus 64-76 23759400-3 2013 METHODS: The enzyme cellobiose dehydrogenase (CDH) was adsorbed on the surface of a carbon working electrode and covalently bound by cross linking. Carbon 84-90 choline dehydrogenase Homo sapiens 20-44 23759400-3 2013 METHODS: The enzyme cellobiose dehydrogenase (CDH) was adsorbed on the surface of a carbon working electrode and covalently bound by cross linking. Carbon 84-90 choline dehydrogenase Homo sapiens 46-49 15301945-1 2004 The direct electrochemistry of myoglobin (Mb) immobilized on a hexagonal mesoporous silica (HMS)-modified glassy carbon electrode was described. Carbon 113-119 myoglobin Homo sapiens 31-40 22528768-0 2013 (1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF). Carbon 11-12 cerebral dopamine neurotrophic factor Homo sapiens 73-110 22528768-0 2013 (1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF). Carbon 11-12 cerebral dopamine neurotrophic factor Homo sapiens 112-116 17506110-4 2007 A strain with the disrupted PEX5 gene (pex5Delta) lost its ability to grow on peroxisome-inducible carbon sources, methanol and oleate, but grew normally on glucose and glycerol. Carbon 99-105 Pex5p Saccharomyces cerevisiae S288C 28-32 15301945-1 2004 The direct electrochemistry of myoglobin (Mb) immobilized on a hexagonal mesoporous silica (HMS)-modified glassy carbon electrode was described. Carbon 113-119 myoglobin Homo sapiens 42-44 17562012-5 2007 Specifically, we describe phylogenies of three core carbon metabolic enzymes: transketolase, glyceraldehyde-3-phosphate dehydrogenase and ribulose-5-phosphate-3-epimerase. Carbon 52-58 ribulose-5-phosphate-3-epimerase Homo sapiens 138-170 15282298-4 2004 In this report we show that in vivo, in cells grown in a medium promoting vegetative growth with acetate as the sole carbon source (SA medium), Rim11 phosphorylates Ime1, the master transcriptional activator required for entry into the meiotic cycle and for the transcription of early meiosis-specific genes. Carbon 117-123 serine/threonine protein kinase RIM11 Saccharomyces cerevisiae S288C 144-149 17568546-0 2007 Expression of MMP-13 in osteoblast cells and rat tibia after exposure to gamma rays or accelerated carbon ions. Carbon 99-105 matrix metallopeptidase 13 Rattus norvegicus 14-20 17568546-7 2007 Carbon ion-irradiated rats exhibited weak expression of MMP-13 around the cartilage inside the trabeculae. Carbon 0-6 matrix metallopeptidase 13 Rattus norvegicus 56-62 17568546-8 2007 We conclude that carbon ion irradiation reduced expression of MMP-13, thus suppressing both chondrocyte maturation and cartilage resorption. Carbon 17-23 matrix metallopeptidase 13 Rattus norvegicus 62-68 23400775-2 2013 We found previously that increased carbon flux from glucose-6-phosphate (G6P) through the pentose phosphate pathway in egg extracts maintains NADPH levels and calcium/calmodulin regulated protein kinase II (CaMKII) activity to phosphorylate caspase 2 and suppress cell death pathways. Carbon 35-41 calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog Xenopus laevis 207-213 23400775-2 2013 We found previously that increased carbon flux from glucose-6-phosphate (G6P) through the pentose phosphate pathway in egg extracts maintains NADPH levels and calcium/calmodulin regulated protein kinase II (CaMKII) activity to phosphorylate caspase 2 and suppress cell death pathways. Carbon 35-41 caspase 2 L homeolog Xenopus laevis 241-250 15202900-4 2004 The key to the synthesis of 4 involves the stereoselective introduction of the hydroxymethyl group onto the C-4 carbon of the pyranose sugar. Carbon 112-118 complement C4A (Rodgers blood group) Homo sapiens 108-111 23413920-3 2013 These thin films were characterized with SEM and TEM as well as FTIR to demonstrate that the carbon nanotubes are embedded within the polyamide and form ester bonds with trimesoyl chloride, one of the monomers of polyamide. Carbon 93-99 MFT2 Homo sapiens 49-52 23244494-2 2013 In particular, it has been shown that 2D molecular descriptors such as fraction of Sp3 carbon atoms (Fsp3) and number of stereo centers correlate with clinical success. Carbon 87-93 NIPA magnesium transporter 1 Homo sapiens 101-105 17557249-4 2007 RESULTS: C311S and G148A polymorphisms of PON2 gene existed among population of Chinese Hunan area, with the allele frequencies 0.23/0.77 for C/S and 0.57/0.43 for G/A in the control group. Carbon 9-10 paraoxonase 2 Homo sapiens 42-46 15158482-2 2004 To clarify the utility of electron microscopy as a quantitative assay for tau fibrillization in vitro, the interaction between synthetic tau filaments and carbon/formvar-coated grids was characterized in detail. Carbon 155-161 microtubule associated protein tau Homo sapiens 137-140 17417840-0 2007 Spin-state selective carbon-detected HNCO with TROSY optimization in all dimensions and double echo-antiecho sensitivity enhancement in both indirect dimensions. Carbon 21-27 spindlin 1 Homo sapiens 0-4 17436239-1 2007 Folates are carriers of one-carbon units and are metabolized by 5,10-methylenetetrahydrofolate reductase (MTHFR) and other enzymes that use riboflavin, cobalamin, or vitamin B6 as cofactors. Carbon 28-34 methylenetetrahydrofolate reductase Homo sapiens 64-104 23281478-5 2013 Yeast mutants lacking the mitochondrial matrix superoxide dismutase (SOD2) enzyme, but not the cytosolic Cu,Zn-SOD1 enzyme, exhibited marked acceleration in production of acid on non-fermentable carbon sources. Carbon 195-201 superoxide dismutase SOD2 Saccharomyces cerevisiae S288C 69-73 23440601-5 2013 For ions interacting with carbon surfaces, inclusion of polarization is essential, and OPLS-AAP is found to perform well in comparison to the highest-level quantum mechanical methods. Carbon 26-32 serpin family F member 2 Homo sapiens 92-95 17436239-1 2007 Folates are carriers of one-carbon units and are metabolized by 5,10-methylenetetrahydrofolate reductase (MTHFR) and other enzymes that use riboflavin, cobalamin, or vitamin B6 as cofactors. Carbon 28-34 methylenetetrahydrofolate reductase Homo sapiens 106-111 23440601-6 2013 Overall, OPLS-AAP provides an accurate and computationally efficient force field for modeling condensed-phase systems featuring carbon surfaces. Carbon 128-134 serpin family F member 2 Homo sapiens 14-17 15170323-1 2004 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate serving as the one-carbon carrier. Carbon 143-149 serine hydroxymethyltransferase 1 Homo sapiens 0-31 23149626-0 2013 The influence of carbon content on the structure and properties of MoS(x)C(y) photocatalysts for light-driven hydrogen generation. Carbon 17-23 MOS proto-oncogene, serine/threonine kinase Homo sapiens 67-70 23149626-1 2013 Carbon containing nano-sized molybdenum sulfide composites (MoS(x)C(y)) obtained by thermal decomposition reactions of (R(4)N)(2)MoS(4) (R = -H (C(0)), -CH(3) (C(1)), -C(3)H(7) (C(3)), and -C(6)H(13) (C(6))) show promising performance in visible-light driven photocatalytic hydrogen generation. Carbon 0-6 MOS proto-oncogene, serine/threonine kinase Homo sapiens 60-63 23149626-1 2013 Carbon containing nano-sized molybdenum sulfide composites (MoS(x)C(y)) obtained by thermal decomposition reactions of (R(4)N)(2)MoS(4) (R = -H (C(0)), -CH(3) (C(1)), -C(3)H(7) (C(3)), and -C(6)H(13) (C(6))) show promising performance in visible-light driven photocatalytic hydrogen generation. Carbon 0-6 MOS proto-oncogene, serine/threonine kinase Homo sapiens 129-132 23149626-1 2013 Carbon containing nano-sized molybdenum sulfide composites (MoS(x)C(y)) obtained by thermal decomposition reactions of (R(4)N)(2)MoS(4) (R = -H (C(0)), -CH(3) (C(1)), -C(3)H(7) (C(3)), and -C(6)H(13) (C(6))) show promising performance in visible-light driven photocatalytic hydrogen generation. Carbon 0-6 complement C3 Homo sapiens 167-182 17321547-5 2007 A new activity of Msi1p was identified: the ability to activate transcription of a reporter gene when tethered near the promoter, but only in the absence of fermentable carbon sources. Carbon 169-175 Msi1p Saccharomyces cerevisiae S288C 18-23 17303418-3 2007 Analogs with the same configuration at carbon atom C-2 as in natural salvinorin A showed higher affinity to KOR than their corresponding epimers. Carbon 39-45 opioid receptor kappa 1 Homo sapiens 108-111 15170323-1 2004 Serine hydroxymethyltransferase (SHMT) catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate serving as the one-carbon carrier. Carbon 143-149 serine hydroxymethyltransferase 1 Homo sapiens 33-37 15110288-1 2004 Bi-enzyme sensor based on thick-film epoxy-carbon electrode modified with polytyramine has been developed and examined for the determination of peroxidase substrates and cholinesterase inhibitors. Carbon 43-49 butyrylcholinesterase Homo sapiens 170-184 17552234-4 2007 As an enzyme of the later ergosterol biosynthesis, the sterol C-22 desaturase encoded by ERG5 gene is required to form the C-22 (23) double bond in the sterol side chain. Carbon 62-63 C-22 sterol desaturase Saccharomyces cerevisiae S288C 89-93 23237914-1 2013 We demonstrate a practical sensing platform, consisting of SnO(2) nanoparticle-decorated semiconducting single-walled carbon nanotubes assembled on gold electrodes via a dielectrophoretic process, for highly sensitive CO detection with fast response at room temperature. Carbon 118-124 strawberry notch homolog 2 Homo sapiens 59-62 14998997-11 2004 Furthermore, the knock-out of ggc1 results in lack of growth on nonfermentable carbon sources and complete loss of mitochondrial DNA. Carbon 79-85 Ggc1p Saccharomyces cerevisiae S288C 30-34 22794932-1 2013 We report for the first time the development of a sensitive and selective glucose biosensor based on the self-assembling of multiwall carbon nanotubes (MWCNTs) dispersed in polyhistidine (Polyhis) and glucose oxidase (GOx) on glassy carbon electrodes (GCE). Carbon 134-140 hydroxyacid oxidase 1 Homo sapiens 201-216 22794932-1 2013 We report for the first time the development of a sensitive and selective glucose biosensor based on the self-assembling of multiwall carbon nanotubes (MWCNTs) dispersed in polyhistidine (Polyhis) and glucose oxidase (GOx) on glassy carbon electrodes (GCE). Carbon 134-140 hydroxyacid oxidase 1 Homo sapiens 218-221 22794932-1 2013 We report for the first time the development of a sensitive and selective glucose biosensor based on the self-assembling of multiwall carbon nanotubes (MWCNTs) dispersed in polyhistidine (Polyhis) and glucose oxidase (GOx) on glassy carbon electrodes (GCE). Carbon 233-239 hydroxyacid oxidase 1 Homo sapiens 201-216 22794932-1 2013 We report for the first time the development of a sensitive and selective glucose biosensor based on the self-assembling of multiwall carbon nanotubes (MWCNTs) dispersed in polyhistidine (Polyhis) and glucose oxidase (GOx) on glassy carbon electrodes (GCE). Carbon 233-239 hydroxyacid oxidase 1 Homo sapiens 218-221 17407076-8 2007 CONCLUSION: These results suggest that R219K polymorphism in ABCA1 gene is not only associated with serum HDL-C and TG levels in healthy Chinese subjects in Chengdu area, but also with HDL-C level and TC/HDL-C ratio in subjects with endogenous HTG. Carbon 0-1 ATP binding cassette subfamily A member 1 Homo sapiens 61-66 19071539-4 2007 Optimisation in batch mode, using amperometric detection at fixed potential, showed the PNR-GOx modified carbon-film electrodes to be best for flow analysis for both glutaraldehyde and sol-gel enzyme immobilisation. Carbon 105-111 hydroxyacid oxidase 1 Homo sapiens 92-95 19071561-1 2007 A new amperometric biosensor for glucose was developed based on adsorption of glucose oxidase (GOx) at the gold and platinum nanoparticles-modified carbon nanotube (CNT) electrode. Carbon 148-154 hydroxyacid oxidase 1 Homo sapiens 78-93 19071561-1 2007 A new amperometric biosensor for glucose was developed based on adsorption of glucose oxidase (GOx) at the gold and platinum nanoparticles-modified carbon nanotube (CNT) electrode. Carbon 148-154 hydroxyacid oxidase 1 Homo sapiens 95-98 22795531-4 2013 The direct electrochemistry of GOx was revealed at the RGO-GOx modified glassy carbon electrode (GCE). Carbon 79-85 hydroxyacid oxidase 1 Homo sapiens 31-34 22795531-4 2013 The direct electrochemistry of GOx was revealed at the RGO-GOx modified glassy carbon electrode (GCE). Carbon 79-85 hydroxyacid oxidase 1 Homo sapiens 59-62 15121831-1 2004 Utilization of nonfermentable carbon sources by Kluyveromyces lactis and Saccharomyces cerevisiae requires the Snf1p kinase and the Cat8p transcriptional activator, which binds to carbon source-responsive elements of target genes. Carbon 30-36 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 132-137 23206891-6 2013 The hemorrhages in the brain are rescued by prior exogenous supplementation with geranylgeranyl pyrophosphate (GGPP), a 20-carbon metabolite of the HMGCR pathway, required for the membrane localization and activation of Rho GTPases. Carbon 123-129 3-hydroxy-3-methylglutaryl-Coenzyme A reductase Mus musculus 148-153 23862620-5 2013 In the past half decade, deorphanization of several GPCRs has revealed that GPR40, GPR41, GPR43, GPR84 and GPR120 sense concentration of extracellular FFAs with various carbon chain lengths. Carbon 169-175 G protein-coupled receptor 84 Homo sapiens 97-102 17302458-6 2007 The carbon spectrum showed two peaks in the carbonyl carbon region of nearly equal intensities at -151.6 degrees C, with E-2 (48%) absorbing downfield of the major Z-2 (52%). Carbon 4-10 cystatin 12, pseudogene Homo sapiens 121-124 17465211-7 2007 The DPD mRNA levels (0.295 vs. 0.381, p = 0.2460) and OPRT/DPD ratio (5.535 vs. 4.394. p = 0.226) had a weak correlation with the T/C ratio. Carbon 132-133 dihydropyrimidine dehydrogenase Homo sapiens 4-7 15121831-1 2004 Utilization of nonfermentable carbon sources by Kluyveromyces lactis and Saccharomyces cerevisiae requires the Snf1p kinase and the Cat8p transcriptional activator, which binds to carbon source-responsive elements of target genes. Carbon 180-186 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 132-137 14679193-9 2004 (ii) Gln3-Myc(13) is hyperphosphorylated during nitrogen and carbon starvation, but this uniform response does not correlate with Gln3 intracellular localization. Carbon 61-67 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 5-9 16920014-7 2007 OLE1 is regulated through Spt23p and Mga2p by multiple systems that control its transcription and mRNA stability in response to diverse stimuli that include nutrient fatty acids, carbon source, metal ions and the availability of oxygen. Carbon 179-185 stearoyl-CoA 9-desaturase Saccharomyces cerevisiae S288C 0-4 17103398-1 2007 A series of cyclic hydrocarbons analogs where a carbon displays unusual planar tetracoordinate structure is proposed, employing hybrid density functional theory calculations using B3LYP functional and 6-311+G** basis set. Carbon 24-30 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 182-185 23115037-1 2013 In many bacteria, the second messenger cyclic AMP (cAMP) interacts with the transcription factor cAMP receptor protein (CRP), forming active cAMP-CRP complexes that can control a multitude of cellular activities, including expanded carbon source utilization, stress response pathways, and virulence. Carbon 232-238 catabolite gene activator protein Escherichia coli 97-118 23115037-1 2013 In many bacteria, the second messenger cyclic AMP (cAMP) interacts with the transcription factor cAMP receptor protein (CRP), forming active cAMP-CRP complexes that can control a multitude of cellular activities, including expanded carbon source utilization, stress response pathways, and virulence. Carbon 232-238 catabolite gene activator protein Escherichia coli 120-123 23115037-1 2013 In many bacteria, the second messenger cyclic AMP (cAMP) interacts with the transcription factor cAMP receptor protein (CRP), forming active cAMP-CRP complexes that can control a multitude of cellular activities, including expanded carbon source utilization, stress response pathways, and virulence. Carbon 232-238 C-reactive protein, pentraxin-related Mus musculus 146-149 23199576-4 2013 Carbon isotopic data suggest a wide range of foraging strategies, characterized by mixed C(3)/C(4) to C(4)-dominated diets in wooded grasslands to open woodlands. Carbon 0-6 complement C3 Homo sapiens 89-93 17099081-8 2007 Detoxification of LysoPC by reacylation occurred in both the H99 wild-type and the Deltaplb1 strains in the presence of glucose, but PLB1 was required when LysoPC was the sole carbon source. Carbon 176-182 phospholipase B1 Homo sapiens 133-137 15233090-1 2004 We examine an approach to three-dimensional pick-and-place assembly of wire-like nanoscale components, such as carbon nanotubes and silicon nanowires, on microstructures inside a scanning electron microscope. Carbon 111-117 protein interacting with PRKCA 1 Homo sapiens 44-48 17182588-4 2007 A robust eosinophil chemotactic activity was released from BSMC stimulated with poly(I:C) and IL-4, which was mostly inhibited by preincubation with an anti-CCL11, but not with an anti-CCL5 Ab. Carbon 62-63 C-C motif chemokine ligand 5 Homo sapiens 185-189 23422565-1 2013 The increasing energy needs of society have led to a search for technologies that can tap carbon-neutral and sustainable energy sources, such as solar and wind. Carbon 90-96 nuclear RNA export factor 1 Homo sapiens 86-89 14969557-5 2004 Loss of the C-1 and C-5 carbon moieties during the formation of 3-mercaptobutan-2-one suggests two different mechanisms leading to the key intermediate butane-2,3-dione. Carbon 24-30 heterogeneous nuclear ribonucleoprotein C Homo sapiens 12-23 23273186-0 2012 Immobilization of malate dehydrogenase on carbon nanotubes for development of malate biosensor. Carbon 42-48 malic enzyme 1 Homo sapiens 18-38 23273186-1 2012 An amperometric malic acid biosensor was developed by immobilizing malate dehydrogenase on multi-walled carbon nanotubes (MWCNT) coated on screen printed carbon electrode. Carbon 104-110 malic enzyme 1 Homo sapiens 67-87 23273186-4 2012 The NADP specific malate dehydrogenase was immobilized on carboxylated multiwalled carbon nanotubes using cross linker EDC [1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide] on screen printed carbon electrode. Carbon 83-89 malic enzyme 1 Homo sapiens 18-38 16352373-1 2007 All higher plants contain at least one microsomal omega-6 desaturase (FAD2), which inserts a double bond between the carbons 12 and 13 of monounsaturated oleic acid to generate polyunsaturated linoleic acid and controls most of the polyunsaturated lipid synthesis in plant cells. Carbon 117-124 delta(12)-acyl-lipid-desaturase-like Nicotiana tabacum 39-68 16352373-1 2007 All higher plants contain at least one microsomal omega-6 desaturase (FAD2), which inserts a double bond between the carbons 12 and 13 of monounsaturated oleic acid to generate polyunsaturated linoleic acid and controls most of the polyunsaturated lipid synthesis in plant cells. Carbon 117-124 delta(12)-acyl-lipid-desaturase-like Nicotiana tabacum 70-74 17304849-3 2006 The results showed that PBS could be only decomposed under attack of microbial enzymes and provided the carbon source for biomass. Carbon 104-110 translocator protein Homo sapiens 24-27 23273186-4 2012 The NADP specific malate dehydrogenase was immobilized on carboxylated multiwalled carbon nanotubes using cross linker EDC [1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide] on screen printed carbon electrode. Carbon 190-196 malic enzyme 1 Homo sapiens 18-38 17304849-5 2006 The main monomer gradients of PBS, such as starch and ethylene, could all be utilized as carbon source by denitrifiers. Carbon 89-95 translocator protein Homo sapiens 30-33 14764708-2 2004 A structure of CD1b complexed with relatively short acyl chain glycolipids plus detergent suggested how an interlinked network of channels within the Ag-binding groove could accommodate acyl chain lengths of up to 80 carbons. Carbon 217-224 CD1b molecule Homo sapiens 15-19 17723765-1 2006 Tyrosinase [EC 1.14.18.1], immobilized on a rotating disk, catalyzed the oxidation of catechols to o-benzoquinone, whose back electrochemical reduction was detected on glassy carbon electrode surface at -150mV versus Ag/AgCl/NaCl 3M. Carbon 175-181 tyrosinase Homo sapiens 0-10 23036595-3 2012 METHODS: In this work, we describe the characterization of human flavin-containing monooxygenase 3 (hFMO3) in a nanoelectrode system based on AuNPs stabilized with didodecyldimethylammonium bromide (DDAB) on glassy carbon electrodes. Carbon 215-221 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 65-98 23036595-3 2012 METHODS: In this work, we describe the characterization of human flavin-containing monooxygenase 3 (hFMO3) in a nanoelectrode system based on AuNPs stabilized with didodecyldimethylammonium bromide (DDAB) on glassy carbon electrodes. Carbon 215-221 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 100-105 23036595-5 2012 RESULTS: Our results show that AuNPs improve the electrochemical performance of hFMO3 on glassy carbon electrodes by enhancing the electron transfer rate and the current signal-to-noise ratio. Carbon 96-102 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 80-85 14570877-3 2004 Over-expression of Rbp1p in yeast resulted in growth defects on nonfermentable carbon sources, suggesting a function for Rbp1p in mitochondrial biogenesis. Carbon 79-85 Sgn1p Saccharomyces cerevisiae S288C 19-24 17073511-4 2006 When the GOX solution contained single-walled carbon nanotubes (GOX-SWNTs), the oxidation peak currents during cyclic voltammetry increased 1.4-4.0 times, as compared to films without SWNTs. Carbon 46-52 hydroxyacid oxidase 1 Homo sapiens 9-12 17073511-4 2006 When the GOX solution contained single-walled carbon nanotubes (GOX-SWNTs), the oxidation peak currents during cyclic voltammetry increased 1.4-4.0 times, as compared to films without SWNTs. Carbon 46-52 hydroxyacid oxidase 1 Homo sapiens 64-67 15137640-1 2004 Carbon nanotubes prepared by catalytic chemical vapor deposition of hydrocarbon at 650 degrees C show good adsorption capability of Pb2+, Cu2+ and Cd2+ ions from aqueous solution after oxidized with concentrated nitric acid at 140 degrees C for 1 h. The specific surface area and particle size distribution of the as-grown and oxidized CNTs were studied by BET method and laser particle analyzer. Carbon 0-6 CD2 molecule Homo sapiens 147-150 22938569-7 2012 Both multi-walled carbon nanotube and crocidolite treatment induced hyperplastic proliferative lesions of the visceral mesothelium, with their proliferating cell nuclear antigen indices approximately 10-fold that of the vehicle control. Carbon 18-24 proliferating cell nuclear antigen Rattus norvegicus 143-177 16931001-1 2006 Linear unselective CCR3 antagonist leads with IC(50) values in the 200 nM range were converted into low nM binding compounds selective at CCR3 by moving the piperidine nitrogen substituent to the carbon at the 2-position of the ring. Carbon 196-202 C-C motif chemokine receptor 3 Homo sapiens 19-23 14646314-2 2003 In the region of delta 5.0-4.0, the signals of H-1 attached to the same carbon with a hydroxyl, were well separated from each other in CDCl(3). Carbon 72-78 H1.5 linker histone, cluster member Homo sapiens 47-50 16931001-1 2006 Linear unselective CCR3 antagonist leads with IC(50) values in the 200 nM range were converted into low nM binding compounds selective at CCR3 by moving the piperidine nitrogen substituent to the carbon at the 2-position of the ring. Carbon 196-202 C-C motif chemokine receptor 3 Homo sapiens 138-142 17415477-3 2006 The RANKL mRNA/OPG mRNA ratio in carbon ion-irradiated MC3T3-E1 cells was lower, while in gamma-irradiated MC3T3-E1 cells this ratio was higher than in non-irradiated cells. Carbon 33-39 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus 15-18 17415477-5 2006 Staining for tartrate-resistant acid phosphatase (TRAP) in co-cultures showed that carbon ion irradiation suppressed osteoclastogenesis. Carbon 83-89 acid phosphatase 5, tartrate resistant Mus musculus 13-48 17415477-5 2006 Staining for tartrate-resistant acid phosphatase (TRAP) in co-cultures showed that carbon ion irradiation suppressed osteoclastogenesis. Carbon 83-89 acid phosphatase 5, tartrate resistant Mus musculus 50-54 17415477-6 2006 This result is consistent with the lower RANKL/OPG mRNA ratio for carbon ion-irradiated cells. Carbon 66-72 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus 47-50 17415477-7 2006 These results suggest that carbon ion irradiation acts primarily on osteoblastic cells, leading to a decrease in the RANKL/OPG mRNA ratio. Carbon 27-33 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) Mus musculus 123-126 22976113-0 2012 A "ship-in-a-bottle" approach to synthesis of polymer dots@silica or polymer dots@carbon core-shell nanospheres. Carbon 82-88 inositol polyphosphate-5-phosphatase D Homo sapiens 3-7 22976113-1 2012 A "ship-in-a-bottle" approach to the entrapment and assembly of nanometer-sized polymer dots in hollow silica or carbon nanospheres with size-selective micropores is presented. Carbon 113-119 inositol polyphosphate-5-phosphatase D Homo sapiens 3-7 23007636-3 2012 Reaction of [PdL2(NH3)2](PF6)2 with hydrazine led to a mixture of [Pd(L2)2](PF6)2 (9) and [PdL2(NH2N=C(CH3)NHNH2)](PF6)2 (10). Carbon 101-102 programmed cell death 1 ligand 2 Homo sapiens 13-17 23007636-3 2012 Reaction of [PdL2(NH3)2](PF6)2 with hydrazine led to a mixture of [Pd(L2)2](PF6)2 (9) and [PdL2(NH2N=C(CH3)NHNH2)](PF6)2 (10). Carbon 101-102 programmed cell death 1 ligand 2 Homo sapiens 91-95 17252785-0 2006 Synthesis of carbon nanotubes using mesoporous Fe-MCM-41 catalysts. Carbon 13-19 methylmalonyl-CoA mutase Homo sapiens 50-53 12970164-6 2003 Leptin led to a nitric oxide (NO) synthase (NOS)-specific, dose-dependent increase in NO production from PBMCs because leptin-induced NO release was blocked by the addition of the NOS inhibitor Nomega-Nitro-l-arginine methyl ester and protein kinase C (PKC) inhibitor calphostin C. Carbon 108-109 leptin Homo sapiens 0-6 17252806-0 2006 DNA as a support for glucose oxidase immobilization at Prussian blue-modified glassy carbon electrode in biosensor preparation. Carbon 85-91 hydroxyacid oxidase 1 Homo sapiens 21-36 17252806-1 2006 An amperometric glucose biosensor has been developed using DNA as a matrix of Glucose oxidase (GOx) at Prussian-blue (PB)-modified glassy carbon (GC) electrode. Carbon 138-144 hydroxyacid oxidase 1 Homo sapiens 78-93 17252806-1 2006 An amperometric glucose biosensor has been developed using DNA as a matrix of Glucose oxidase (GOx) at Prussian-blue (PB)-modified glassy carbon (GC) electrode. Carbon 138-144 hydroxyacid oxidase 1 Homo sapiens 95-98 17138693-0 2006 C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis. Carbon 0-1 cytochrome P450, family 90, subfamily D, polypeptide 1 Arabidopsis thaliana 46-53 16783006-9 2006 This article reveals that the key components of the glucose-signaling pathway are conserved between S. cerevisiae and K. lactis, but points out major differences in Rgt1 regulation and function that might reflect different carbon metabolism of these yeasts. Carbon 223-229 Rgt1p Saccharomyces cerevisiae S288C 165-169 16905358-2 2006 The first known member Nar1.1 encodes a chloroplast nitrite transporter that regulates nitrate assimilation according to carbon availability, and data supporting the idea that NAR1 proteins may participate in adjusting both nitrite and carbon utilization by Chlamydomonas cells are presented herein. Carbon 121-127 NAR1.1 Chlamydomonas reinhardtii 23-29 16905358-2 2006 The first known member Nar1.1 encodes a chloroplast nitrite transporter that regulates nitrate assimilation according to carbon availability, and data supporting the idea that NAR1 proteins may participate in adjusting both nitrite and carbon utilization by Chlamydomonas cells are presented herein. Carbon 236-242 NAR1.1 Chlamydomonas reinhardtii 23-29 17129494-8 2006 HIF-1alpha protein was barely positive in C group (0.080 +/- 0.009), but markedly up-regulated in H(3) group (0.196 +/- 0.018, compared with C group q = 18.864, P < 0.05), reaching its peak in H(7) group (0.203 +/- 0.022), and then declined slightly in H(14) and H(21) group. Carbon 42-43 hypoxia inducible factor 1 subunit alpha Rattus norvegicus 0-10 16945026-1 2006 BACKGROUND: Polymorphisms in the promoter region of the interleukin (IL)-10 gene have been identified at positions -1082 (G-->A), -819 (C-->T), and -592 (C-->A). Carbon 2-3 interleukin 10 Homo sapiens 56-75 16510264-3 2006 A downstream biological response, differential upregulation of intercellular adhesion molecule (ICAM)-1, was measurable using fluorescence microscopy in the air-liquid interface human lung cell cultures even though the dose per culture was 0-100 lipopolysaccharide (LPS)-containing elemental carbon particles (52 pg LPS per 6.3 microm diameter particle). Carbon 292-298 intercellular adhesion molecule 1 Homo sapiens 63-103 16873121-1 2006 B12-dependent methylmalonyl-CoA mutase catalyses the interchange of a hydrogen atom and the carbonyl-CoA group on adjacent carbons of methylmalonyl-CoA to give the rearranged product, succinyl-CoA. Carbon 123-130 methylmalonyl-CoA mutase Homo sapiens 14-38 16883446-7 2006 A significantly lower C/S rate (x2=21.9, p<0.0005) was found among women induced with prostaglandin (PG) alone (19.4%) compared with those induced with PG and oxytocin, whether oxytocin was given ideally (38.3%) or not ideally (45.4%). Carbon 22-23 oxytocin/neurophysin I prepropeptide Homo sapiens 162-170 16883446-7 2006 A significantly lower C/S rate (x2=21.9, p<0.0005) was found among women induced with prostaglandin (PG) alone (19.4%) compared with those induced with PG and oxytocin, whether oxytocin was given ideally (38.3%) or not ideally (45.4%). Carbon 22-23 oxytocin/neurophysin I prepropeptide Homo sapiens 180-188 16787057-2 2006 The present studies show that enhancement of carbon acidity of alpha-amino acids by cofactor pyridoxal 5"-phosphate, PLP, with an unusual, unprotonated pyridine is due to solvation effects, in contrast to the intrinsic electron-withdrawing stabilization by the pyridinium ion to form a quinonoid intermediate. Carbon 45-51 proteolipid protein 1 Homo sapiens 117-120 16768462-1 2006 IalphaI and TSG-6 interact to form a covalent bond between the C-terminal Asp alpha-carbon of an IalphaI heavy chain (HC) and an unknown component of TSG-6. Carbon 84-90 TNF alpha induced protein 6 Homo sapiens 12-17 16916220-5 2006 Detailed C 1s narrow scan spectrum of the Er:YAG laser-irradiated enamel surface showed that C-O/C-N, C = O/-CON=, -COO-, and CO,3(2-) components, attributed to the specific composition of enamel and any common carbon contamination in surplus, relatively decreased. Carbon 93-94 complement C1s Bos taurus 9-13 16706452-0 2006 Kinetic isotope effect for H2 and D2 quantum molecular sieving in adsorption/desorption on porous carbon materials. Carbon 98-104 relaxin 2 Homo sapiens 27-36 16637655-0 2006 C7 and C9 carbon-rich bridges in diruthenium systems: synthesis, spectroscopic, and theoretical investigations of different oxidation States. Carbon 10-16 complement C7 Homo sapiens 0-9 16749860-13 2006 Overall, C-24 ionic character influenced interaction with hASBT. Carbon 9-10 solute carrier family 10 member 2 Homo sapiens 58-63 16680245-1 2006 OBJECTIVE: To investigate the association of the 2 intracellular adhesion molecules-1 (ICAM-1) gene polymorphisms [thymidine/cytidine (T/C) 469 and guanosine/adenosine (G/A) 241] in Behcets disease in Lebanon. Carbon 4-5 intercellular adhesion molecule 1 Homo sapiens 87-93 16490786-1 2006 The role of the Saccharomyces cerevisae peroxisomal acyl-coenzyme A (acyl-CoA) thioesterase (Pte1p) in fatty acid beta-oxidation was studied by analyzing the in vitro kinetic activity of the purified protein as well as by measuring the carbon flux through the beta-oxidation cycle in vivo using the synthesis of peroxisomal polyhydroxyalkanoate (PHA) from the polymerization of the 3-hydroxyacyl-CoAs as a marker. Carbon 236-242 palmitoyl-CoA hydrolase Saccharomyces cerevisiae S288C 93-98 16553903-6 2006 This spatiotemporal characterization of carbon metabolism has also been applied to various mutants disrupted in embryo development including gnom (gn), acetyl-CoA carboxylase1 (acc1), schlepperless (slp), and wrinkled1 (wri1). Carbon 40-46 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 209-218 16361229-3 2006 Moreover, we provide evidence that Glc7-Reg1 phosphatase acts as an upstream activator of Yck1,2 kinases in a novel signaling pathway that modulates kinase activity in response to carbon source availability. Carbon 180-186 serine/threonine protein kinase YCK1 Saccharomyces cerevisiae S288C 90-96 16201964-8 2006 In order to define specific contributions of ISC1, microarray hybridizations were performed, and analyses showed misregulation of genes involved in carbon source utilization and sexual reproduction, which was corroborated by defining a sporulation defect of the isc1Delta strain. Carbon 148-154 inositol phosphosphingolipid phospholipase Saccharomyces cerevisiae S288C 45-49 16291748-12 2006 The delta ndt1 delta ndt2 double mutant exhibited lower mitochondrial NAD+ and NADH levels than the single deletants and a more pronounced delay in growth on nonfermentable carbon sources. Carbon 173-179 NAD+ transporter Saccharomyces cerevisiae S288C 21-25 16433354-2 2006 After 14 days of lamp irradiation, BDE-209 degraded with a half-life of 36 and 44 days, respectively, on montmorillonite or kaolinite, with much slower degradation occurring when sorbed on organic carbon-rich natural sediment (t1/2 = 150 days). Carbon 197-203 homeobox D13 Homo sapiens 35-38 17000537-6 2006 Aliphatic and aromatic carbons are incorporated in the model by the inclusion of pertinent variables such as C/N and Br/Cl2 in the algorithm. Carbon 23-30 endogenous retrovirus group W member 5 Homo sapiens 120-123 17018414-5 2006 The BOD5/TOC (5-day biological oxygen demand/total organic carbons) ratios of the ozonated Reactive Red 120 and Acid Red 299 solutions would increase and have the maximum values. Carbon 59-66 rhomboid 5 homolog 2 Homo sapiens 9-12 16316145-1 2005 Hexagonally structured mesoporous carbons C15 and CMK-5 and cubically structured carbon C48 were synthesized using ordered silica SBA-15 and MCM-48 as templates and carbon precursors of different structures. Carbon 81-87 CDK5 regulatory subunit associated protein 2 Homo sapiens 88-91 16316145-10 2005 The chemical modification process considerably reduced the primary mesopores in these ordered carbons by approximately 1-1.5 nm, affording carbons with micropores in the cases of C15 and C48, and mixed micropores and small mesopores in the case of CMK-5. Carbon 94-101 placenta associated 8 Homo sapiens 179-182 16316145-10 2005 The chemical modification process considerably reduced the primary mesopores in these ordered carbons by approximately 1-1.5 nm, affording carbons with micropores in the cases of C15 and C48, and mixed micropores and small mesopores in the case of CMK-5. Carbon 94-101 CDK5 regulatory subunit associated protein 2 Homo sapiens 187-190 16428296-2 2005 Here, using nordihydroguaiaretic acid (NDGA), with two phenyl rings connected by a four-carbon chain, as a representative, the structural basis for the inhibition of animal fatty acid synthase (FAS) by polyphenols was investigated. Carbon 88-94 fatty acid synthase Homo sapiens 173-192 16428296-2 2005 Here, using nordihydroguaiaretic acid (NDGA), with two phenyl rings connected by a four-carbon chain, as a representative, the structural basis for the inhibition of animal fatty acid synthase (FAS) by polyphenols was investigated. Carbon 88-94 fatty acid synthase Homo sapiens 194-197 16133214-1 2005 The PII signal transducing protein is involved in carbon/nitrogen (C/N) sensing in bacteria and cyanobacteria. Carbon 50-56 nitrogen regulatory P-II-like protein Arabidopsis thaliana 4-7 16133214-1 2005 The PII signal transducing protein is involved in carbon/nitrogen (C/N) sensing in bacteria and cyanobacteria. Carbon 67-68 nitrogen regulatory P-II-like protein Arabidopsis thaliana 4-7 15886002-1 2005 The amperometric detection of neurotransmitters metabolite of 3,4-dihydroxyphenylacetic acid (DOPAC) was achieved at a tyrosinase-chitosan composite film-modified glassy carbon (GC) electrode. Carbon 170-176 tyrosinase Homo sapiens 119-129 16246072-5 2005 This strain is respiratory competent, but unlike the ETR1 wild-type strain, it is sensitive to triclosan on media containing only non-fermentable carbon source. Carbon 146-152 enoyl-[acyl-carrier-protein] reductase Saccharomyces cerevisiae S288C 53-57 16141204-3 2005 This work demonstrates that the gluconeogenic genes in Escherichia coli, ppsA, sfcA, and maeB, provide a feedback loop to the global regulator, cAMP receptor protein (CRP), in carbon source transition. Carbon 176-182 catabolite gene activator protein Escherichia coli 144-165 16141204-3 2005 This work demonstrates that the gluconeogenic genes in Escherichia coli, ppsA, sfcA, and maeB, provide a feedback loop to the global regulator, cAMP receptor protein (CRP), in carbon source transition. Carbon 176-182 catabolite gene activator protein Escherichia coli 167-170 16075440-5 2005 The racemization process could be completely depressed by keeping the reaction temperature at -78 degrees C. The construction of the stereogenic quaternary carbon center was achieved by the lipase-catalyzed desymmetrization of the prochiral 1,3-diol 9 a bearing the DEF-ring moiety. Carbon 156-162 UTP25 small subunit processome component Homo sapiens 266-269 16190722-10 2005 Characterization of the dried Ni/CNF-O samples with TEM and XRD showed well dispersed and thin (5 nm) platelets of nickel hydroxide adhering to the carbon nanofibers. Carbon 148-154 NPHS1 adhesion molecule, nephrin Homo sapiens 33-36 16128814-4 2005 A carbon source-conditional strain with the NOP53 coding sequence under the control of the GAL1 promoter did not grow in glucose-containing medium, showing the phenotype of an essential gene. Carbon 2-8 Nop53p Saccharomyces cerevisiae S288C 44-49 23106489-5 2012 However, the intermolecular bond bundles in crystalline RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) change from C-N trigger linkages in the gas phase to N-N trigger linkages in the solid state. Carbon 114-115 radixin Homo sapiens 56-59 23017870-6 2012 The RBE values for the carbon ion beam relative to X-ray at the D10 levels for CD44(+)/CD24(+) cells were 2.0-2.19. Carbon 23-29 CD44 molecule (Indian blood group) Homo sapiens 79-83 23017870-7 2012 The number of gammaH2AX foci in CD44(-)/CD24(-) cells was higher than that of CD44(+)/CD24(+) cells after irradiation with either X-ray or carbon ion beam. Carbon 139-145 CD44 molecule (Indian blood group) Homo sapiens 32-36 23017870-7 2012 The number of gammaH2AX foci in CD44(-)/CD24(-) cells was higher than that of CD44(+)/CD24(+) cells after irradiation with either X-ray or carbon ion beam. Carbon 139-145 CD44 molecule (Indian blood group) Homo sapiens 78-82 23032298-5 2012 We further investigate the possibility of creating the pressures required to stabilize H4M through external agents such as metal organic framework (MOF) materials and carbon nanotubes, with very encouraging results. Carbon 167-173 H4 clustered histone 9 Homo sapiens 87-90 23032298-7 2012 On the other hand, we find that all the investigated carbon nanotubes can create the high pressures required for H4M to be stable at room temperature, with direct implications for new and exciting hydrogen-storage applications. Carbon 53-59 H4 clustered histone 9 Homo sapiens 113-116 22874974-5 2012 In particular, the bromination on beta-pyrrole carbon atoms of the meso-substituted (oxo)manganese(V) corrole strikingly enhances the spin-orbit coupling interaction and results in the dramatic increase of reactivity. Carbon 47-53 spindlin 1 Homo sapiens 134-138 22776180-2 2012 Integrin alpha5beta1 was adsorbed on the gold-nanoparticle modified glassy carbon electrode to bind integrin beta1 monoclonal antibody (anti-CD29 mAb). Carbon 75-81 integrin subunit beta 1 Homo sapiens 100-114 22907772-8 2012 Over the 4 % Pt/ZrP catalyst, a 94 % carbon yield of diesel and 75 % carbon yield of C15 hydrocarbons (with 6-butylundecane as the major component) was achieved. Carbon 69-75 placenta associated 8 Homo sapiens 85-88 29334046-3 2012 Bis-piperidinium salts possessing 12-16 carbon side chains showed better antimicrobial properties as compared to the standard dodecyltrimethylammonium chloride. Carbon 40-46 Bis protein Escherichia coli 0-3 22934734-2 2012 Clusters of the type [Fe(4)S(4)(SAr)(4)](2-) (Ar = Ph, C(6)H(4)-3-F) are generated in Me(2)SO by redox reactions of [Fe(4)S(4)(SEt)(4)](2-) with 2 equiv of ArSSAr. Carbon 0-1 sarcosine dehydrogenase Homo sapiens 32-35 22865705-1 2012 More than LiP service: The adsorption of red phosphorus into porous carbon provides a composite anode material for lithium-ion batteries. Carbon 68-74 SMG1 nonsense mediated mRNA decay associated PI3K related kinase Homo sapiens 10-13 22052259-1 2012 The methylenetetrahydrofolate reductase (MTHFR) genes and folate in one-carbon metabolism are essential for DNA methylation and synthesis. Carbon 72-78 methylenetetrahydrofolate reductase Homo sapiens 4-39 22052259-1 2012 The methylenetetrahydrofolate reductase (MTHFR) genes and folate in one-carbon metabolism are essential for DNA methylation and synthesis. Carbon 72-78 methylenetetrahydrofolate reductase Homo sapiens 41-46 22811435-2 2012 Here, we show that the nucleus-localized transcription factors GATA NITRATE-INDUCIBLE CARBON-METABOLISM-INVOLVED (GNC) and CYTOKININ-RESPONSIVE GATA1 (CGA1) regulate chloroplast development, growth, and division in Arabidopsis (Arabidopsis thaliana). Carbon 86-92 cytokinin-responsive gata factor 1 Arabidopsis thaliana 123-149 22621912-3 2012 The HMC results are 1x10(-2), 4x10(-3), 8x10(-4), and 2.5x10(-4) mol/L for sodium sulfate salts with a carbon-chain length of C-10, C-12, C-14, and C-16, respectively. Carbon 6-7 chromosome 12 open reading frame 57 Homo sapiens 126-130 22621912-8 2012 Given each surfactant concentration at its respective HMC, the corresponding desorption rates are along the order of C-12<C-14<C-16<-C-10. Carbon 56-57 chromosome 12 open reading frame 57 Homo sapiens 142-146 22621912-8 2012 Given each surfactant concentration at its respective HMC, the corresponding desorption rates are along the order of C-12<C-14<C-16<-C-10. Carbon 117-118 chromosome 12 open reading frame 57 Homo sapiens 142-146 22621912-8 2012 Given each surfactant concentration at its respective HMC, the corresponding desorption rates are along the order of C-12<C-14<C-16<-C-10. Carbon 117-118 chromosome 12 open reading frame 57 Homo sapiens 142-146 22684237-1 2012 A diastereo- and enantioselective aldol reaction between aldehydes and a synthetically useful ketomalonate 1c as a hydrated form was developed, and either anti- or syn-aldol adducts having a chiral tetrasubstituted carbon center were obtained in high enantioselectivities by use of a tetrazole analogue of L-proline (S)-2 or an axially chiral amino sulfonamide (S)-3 as catalyst. Carbon 215-221 synemin Homo sapiens 73-76 22817942-3 2012 In the biosensor, tyrosinase is entrapped in titania gel modified with multiwalled carbon nanotubes (MWCNT) and Nafion. Carbon 83-89 tyrosinase Homo sapiens 18-28 22397761-0 2012 Functionalization of single-walled carbon nanotubes enables efficient intracellular delivery of siRNA targeting MDM2 to inhibit breast cancer cells growth. Carbon 35-41 MDM2 proto-oncogene Homo sapiens 112-116 22576791-17 2012 CONCLUSION: An unbiased C-G Cl(c) (r) can be calculated using actual body weight in underweight patients and ideal body weight in patients of normal weight. Carbon 0-1 Charcot-Leyden crystal galectin Homo sapiens 28-33 22609969-2 2012 After being coated with a thin layer of amorphous carbon, the as-obtained SnO(2)@carbon hollow microspheres are shown to exhibit improved lithium storage properties, delivering a reversible capacity of 570 mA h g(-1) after 50 cycles at a high current density of 400 mA g(-1). Carbon 50-56 strawberry notch homolog 2 Homo sapiens 74-77 22609969-2 2012 After being coated with a thin layer of amorphous carbon, the as-obtained SnO(2)@carbon hollow microspheres are shown to exhibit improved lithium storage properties, delivering a reversible capacity of 570 mA h g(-1) after 50 cycles at a high current density of 400 mA g(-1). Carbon 81-87 strawberry notch homolog 2 Homo sapiens 74-77 22651861-1 2012 Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions were studied with potassium Boc-protected aminomethyltrifluoroborate through C-O activation of various mesylate derivatives to afford the corresponding products in moderate to good yields. Carbon 137-138 BOC cell adhesion associated, oncogene regulated Homo sapiens 88-91 22719553-3 2012 In each mol-ecule, there is a twist in the link between the approximately syn carbonyl and amine groups [the N-C-C-O torsion angles range from 19.73 (19) to -21.2 (2) ]. Carbon 111-112 synemin Homo sapiens 74-77 22719553-3 2012 In each mol-ecule, there is a twist in the link between the approximately syn carbonyl and amine groups [the N-C-C-O torsion angles range from 19.73 (19) to -21.2 (2) ]. Carbon 113-114 synemin Homo sapiens 74-77 22513256-3 2012 For quantitative analysis of bio-oil, the relative response factor (RRF) of each component was calculated using an effective carbon number (ECN) that was multiplied by the peak area of each component detected by a GC-FID. Carbon 125-131 mitochondrial ribosome recycling factor Homo sapiens 68-71 23003173-1 2012 We theoretically investigate the deflection-induced coupling of an electron spin to vibrational motion due to spin-orbit coupling in suspended carbon nanotube quantum dots. Carbon 143-149 spindlin 1 Homo sapiens 76-80 23003173-1 2012 We theoretically investigate the deflection-induced coupling of an electron spin to vibrational motion due to spin-orbit coupling in suspended carbon nanotube quantum dots. Carbon 143-149 spindlin 1 Homo sapiens 110-114 22056068-6 2012 Compared to integrin expression in unirradiated cells, carbon ion irradiation caused decreased integrin expression and inhibited cell migration on both Vn and Fn. Carbon 55-61 vitronectin Homo sapiens 152-154 22056068-8 2012 In contrast to photon RT, carbon ion RT causes decreased integrin expression and suppresses glioma cell migration on both Vn and Fn, thus promising improved local control. Carbon 26-32 vitronectin Homo sapiens 122-124 22158074-8 2012 Serum HSP70 levels in the PC group were significantly higher compared with either the CP or C groups (P < 0.01). Carbon 27-28 heat shock protein family A (Hsp70) member 4 Homo sapiens 6-11 22395232-3 2012 In contrast, less potent cytotoxins discorhabdins D and Q failed to react, supporting an SAR model of cytotoxicity requiring an orchestrated combination of an electrophilic Delta(1) carbon centre and a nucleophilic N-18 amine for potent activity. Carbon 182-188 sarcosine dehydrogenase Homo sapiens 89-92 22475034-1 2012 Bicyclo[3.2.1]oct-6-en-8-ylidene (1) can assume either the conformation of "classical" carbene 1a or that of foiled carbene 1b in which the divalent carbon bends toward the double bond. Carbon 149-155 POU class 3 homeobox 1 Homo sapiens 14-19 22172649-0 2012 A novel tyrosinase biosensor based on chitosan-carbon-coated nickel nanocomposite film. Carbon 47-53 tyrosinase Homo sapiens 8-18 22313416-0 2012 Me3(OMe)tBuXPhos: a surrogate ligand for Me4tBuXPhos in palladium-catalyzed C-N and C-O bond-forming reactions. Carbon 76-77 malic enzyme 3 Homo sapiens 0-3 22259189-0 2012 Disturbed one-carbon metabolism causing adverse reproductive outcomes in mice is associated with altered expression of apolipoprotein AI and inflammatory mediators PPARalpha, interferon-gamma, and interleukin-10. Carbon 14-20 apolipoprotein A-I Mus musculus 119-136 22267127-4 2012 The left-handed (M) helices of the (S,S)-Ac(5)c(dOMe) homochiral homopeptides were exclusively controlled by the side-chain chiral centers, because the cyclic amino acid (S,S)-Ac(5)c(dOMe) does not have an alpha-carbon chiral center but has side-chain gamma-carbon chiral centers. Carbon 212-218 domeless Drosophila melanogaster 48-52 22267127-4 2012 The left-handed (M) helices of the (S,S)-Ac(5)c(dOMe) homochiral homopeptides were exclusively controlled by the side-chain chiral centers, because the cyclic amino acid (S,S)-Ac(5)c(dOMe) does not have an alpha-carbon chiral center but has side-chain gamma-carbon chiral centers. Carbon 258-264 domeless Drosophila melanogaster 48-52 21898369-0 2012 Enzyme precipitate coatings of glucose oxidase onto carbon paper for biofuel cell applications. Carbon 52-58 hydroxyacid oxidase 1 Homo sapiens 31-46 21898369-2 2012 This study describes the direct immobilization of glucose oxidase (GOx) onto the carbon paper in the form of highly stable and active enzyme precipitation coatings (EPCs), which can improve the lifetime and power density of BFCs. Carbon 81-87 hydroxyacid oxidase 1 Homo sapiens 50-65 21898369-2 2012 This study describes the direct immobilization of glucose oxidase (GOx) onto the carbon paper in the form of highly stable and active enzyme precipitation coatings (EPCs), which can improve the lifetime and power density of BFCs. Carbon 81-87 hydroxyacid oxidase 1 Homo sapiens 67-70 21898369-4 2012 GOx-immobilized carbon papers via the CA and EPC approaches were used as an enzyme anode and their electrochemical activities were tested under the BFC-operating mode. Carbon 16-22 hydroxyacid oxidase 1 Homo sapiens 0-3 22052136-3 2012 In CR5 the highest concentrations of these elements (0.9, 1.4 and 1.7 mug g(-1) respectively) were located at the top of the core within a surface layer enriched in organic carbon. Carbon 173-179 teratocarcinoma-derived growth factor 1 pseudogene 5 Homo sapiens 3-6 23099320-10 2012 Although the mRNA level of D-amino acid oxidase (DAAO) was increased in the prefrontal cortex and hippocampus of neonatal polyI:C-treated mice in adulthood, no changes were observed in D-serine content and DAAO enzymatic activity. Carbon 128-129 D-amino acid oxidase Mus musculus 27-47 23099320-10 2012 Although the mRNA level of D-amino acid oxidase (DAAO) was increased in the prefrontal cortex and hippocampus of neonatal polyI:C-treated mice in adulthood, no changes were observed in D-serine content and DAAO enzymatic activity. Carbon 128-129 D-amino acid oxidase Mus musculus 49-53 21916894-11 2012 Our work indicates that AtLrgB is a new player in chloroplast development, carbon partitioning and leaf senescence, although its molecular mechanism remains to be established. Carbon 75-81 membrane protein Arabidopsis thaliana 24-30 22253227-3 2012 We show that under favorable growth conditions, ATI1 and ATI2 are partially associated with the endoplasmic reticulum (ER) membrane network, whereas upon exposure to carbon starvation, they become mainly associated with newly identified spherical compartments that dynamically move along the ER network. Carbon 166-172 mesoderm induction early response protein Arabidopsis thaliana 57-61 16102431-2 2005 This study reviewed the impact of vitamin E and C supplementation on calcineurin inhibitor trough concentrations. Carbon 48-49 calcineurin binding protein 1 Homo sapiens 69-90 16193985-0 2005 Determination of cardiac troponin I for the auxiliary diagnosis of acute myocardial infarction by anodic stripping voltammetry at a carbon paste electrode. Carbon 132-138 troponin I3, cardiac type Homo sapiens 17-35 16022412-7 2005 Because loss of HCl is also coincident with Hg breakthrough or loss of the divalent Hg ion (Hg2+), the competition of Hg2+ with S(VI) on the basic carbon site is also implied. Carbon 147-153 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 118-121 15941397-0 2005 Identification and expression analysis of two inorganic C- and N-responsive genes encoding novel and distinct molecular forms of eukaryotic phosphoenolpyruvate carboxylase in the green microalga Chlamydomonas reinhardtii. Carbon 56-57 uncharacterized protein Chlamydomonas reinhardtii 140-171 15797337-0 2005 A glucose biosensor based on electrodeposition of palladium nanoparticles and glucose oxidase onto Nafion-solubilized carbon nanotube electrode. Carbon 118-124 hydroxyacid oxidase 1 Homo sapiens 78-93 15797337-1 2005 Electrodeposition was used for the co-deposition of glucose oxidase (GOx) enzymes and palladium nanoparticles onto a Nafion-solubilized carbon nanotube (CNT) film. Carbon 136-142 hydroxyacid oxidase 1 Homo sapiens 52-67 15797337-1 2005 Electrodeposition was used for the co-deposition of glucose oxidase (GOx) enzymes and palladium nanoparticles onto a Nafion-solubilized carbon nanotube (CNT) film. Carbon 136-142 hydroxyacid oxidase 1 Homo sapiens 69-72 22479306-0 2012 Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficient mice. Carbon 76-82 myeloperoxidase Mus musculus 96-111 12970164-6 2003 Leptin led to a nitric oxide (NO) synthase (NOS)-specific, dose-dependent increase in NO production from PBMCs because leptin-induced NO release was blocked by the addition of the NOS inhibitor Nomega-Nitro-l-arginine methyl ester and protein kinase C (PKC) inhibitor calphostin C. Carbon 108-109 leptin Homo sapiens 119-125 22479306-2 2012 Here, we used myeloperoxidase knockout B6.129X1-MPO (MPO k/o) mice and showed that oxidation and clearance of single walled carbon nanotubes (SWCNT) from the lungs of these animals after pharyngeal aspiration was markedly less effective whereas the inflammatory response was more robust than in wild-type C57Bl/6 mice. Carbon 124-130 myeloperoxidase Mus musculus 14-29 22479306-2 2012 Here, we used myeloperoxidase knockout B6.129X1-MPO (MPO k/o) mice and showed that oxidation and clearance of single walled carbon nanotubes (SWCNT) from the lungs of these animals after pharyngeal aspiration was markedly less effective whereas the inflammatory response was more robust than in wild-type C57Bl/6 mice. Carbon 124-130 myeloperoxidase Mus musculus 53-56 15839661-3 2005 Diynamides participate as particularly reactive 2pi components in the cycloaddition, providing access to indolines with carbon substituents at the C-7 position. Carbon 120-126 complement C7 Homo sapiens 147-150 15839686-0 2005 Inclusion of cut and as-grown single-walled carbon nanotubes in the helical superstructure of schizophyllan and curdlan (beta-1,3-glucans). Carbon 44-50 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 121-129 14599211-5 2003 In the case of glycosaminoglycan-derived amidyl radicals, evidence has been obtained in studies with model glycosides that these radicals undergo rapid intramolecular abstraction reactions to give carbon-centered radicals at C-2 on the N-acetyl glycosamine rings (via a 1,2-hydrogen atom shift) and at C-4 on the neighboring uronic acid residues (via 1,5-hydrogen atom shifts). Carbon 197-203 complement C2 Homo sapiens 225-228 18970008-1 2005 The performance of amperometric glucose biosensors based on the dispersion of glucose oxidase (GOx) and copper oxide within a classical carbon (graphite) paste composite is reported in this work. Carbon 136-142 hydroxyacid oxidase 1 Homo sapiens 78-93 18970008-1 2005 The performance of amperometric glucose biosensors based on the dispersion of glucose oxidase (GOx) and copper oxide within a classical carbon (graphite) paste composite is reported in this work. Carbon 136-142 hydroxyacid oxidase 1 Homo sapiens 95-98 22057276-6 2011 In this study, the impact of increased Shmt1 expression on folate-mediated one-carbon metabolism was determined in mice that overexpress the Shmt1 cDNA (Shmt1tg+ mice). Carbon 79-85 serine hydroxymethyltransferase 1 (soluble) Mus musculus 39-44 14599211-5 2003 In the case of glycosaminoglycan-derived amidyl radicals, evidence has been obtained in studies with model glycosides that these radicals undergo rapid intramolecular abstraction reactions to give carbon-centered radicals at C-2 on the N-acetyl glycosamine rings (via a 1,2-hydrogen atom shift) and at C-4 on the neighboring uronic acid residues (via 1,5-hydrogen atom shifts). Carbon 197-203 complement C4A (Rodgers blood group) Homo sapiens 302-305 22151413-7 2011 The FAR1 group mainly synthesized 1-hexadecanol and accepted substrates in the range between 14 and 18 carbon atoms, whereas the FAR2 group preferred stearoyl-CoA and accepted substrates between 16 and 20 carbon atoms. Carbon 103-109 cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1 Saccharomyces cerevisiae S288C 4-8 22151413-7 2011 The FAR1 group mainly synthesized 1-hexadecanol and accepted substrates in the range between 14 and 18 carbon atoms, whereas the FAR2 group preferred stearoyl-CoA and accepted substrates between 16 and 20 carbon atoms. Carbon 205-211 cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1 Saccharomyces cerevisiae S288C 4-8 15863098-4 2005 Beta-galactosidase activity values, shown by lacZ fusions of KlNDI1 promoter deletions, suggested that two Adr1p binding sites mediate this carbon source regulation of KlNDI1. Carbon 140-146 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 107-112 14599211-6 2003 The C-4 carbon-centered radicals, and analogous species derived from model glycosides, undergo pH-independent beta-scission reactions that result in glycosidic bond cleavage. Carbon 8-14 complement C4A (Rodgers blood group) Homo sapiens 4-7 15824167-1 2005 Methylenetetrahydrofolate reductase (MTHFR) balances the pool of folate coenzymes in one-carbon metabolism for DNA synthesis and methylation, both implicated in carcinogenesis. Carbon 89-95 methylenetetrahydrofolate reductase Homo sapiens 0-35 15824167-1 2005 Methylenetetrahydrofolate reductase (MTHFR) balances the pool of folate coenzymes in one-carbon metabolism for DNA synthesis and methylation, both implicated in carcinogenesis. Carbon 89-95 methylenetetrahydrofolate reductase Homo sapiens 37-42 12867346-5 2003 At optimal conditions, complete discoloration of 100 mg/L HE-3B can be achieved in 30 min and the total organic carbon removal ratio can attain 76% in 120 min, illustrating that Fe-Lap-RD has a high photo-catalytic activity in the photo-assisted discoloration and mineralization of HE-3B in the presence of UV light (254 nm) and H2O2. Carbon 112-118 LAP Homo sapiens 181-184 15668256-5 2005 The enzyme can elongate acyl-chains containing 2-14 carbon atoms with malonyl moieties attached in thioester linkage to the human mitochondrial acyl carrier protein and is able to restore growth to the respiratory-deficient yeast mutant cem1 that lacks the endogenous mitochondrial beta-ketoacyl synthase and exhibits lowered lipoic acid levels. Carbon 52-58 fatty acid synthase CEM1 Saccharomyces cerevisiae S288C 237-241 21908639-9 2011 Consistent with this, ALY2- and UBP13-engineered cells of the industrial QA23 strain grew faster and produced more CO2 at 12 C than did the parental when maltose was used as the sole carbon source. Carbon 183-189 ubiquitin-specific protease UBP13 Saccharomyces cerevisiae S288C 32-37 21930517-1 2011 Conventional parameters (loss on ignition, total organic carbon, total nitrogen, C/N-ratio, respiration activity (RA4), compost status (= "Rottegrad"), NH4-N and NO3-N) are not correlated to humification. Carbon 0-1 RA4 Homo sapiens 114-117 12926963-3 2003 In the first step, Pro-1 acts as a general base to abstract a proton from the third carbon of the substrate, 2-oxo-4-hexenedioate, creating a negative charge on the oxygen at C-2 of this substrate. Carbon 84-90 lamin A/C Homo sapiens 19-24 21989811-6 2011 Increased frameshifting on alternative carbon sources also appears to require cytoplasmic localization of Snf1p, mediated by the Sip2p protein. Carbon 39-45 Sip2p Saccharomyces cerevisiae S288C 129-134 21959040-5 2011 Purified ELOVL7 exhibited high activity toward acyl-CoAs with C18 carbon chain length. Carbon 66-72 ELOVL fatty acid elongase 7 Homo sapiens 9-15 16833611-5 2005 For example, the calculated atomic electronegativities show a uniform decrease from C to Pb increasing again to Uuq as verified in the experimental data for C-Pb but at variance with several other scales. Carbon 84-85 carboxypeptidase B1 Homo sapiens 157-161 15771433-3 2005 Attempts to optimize a cyclin-dependent kinase-1 (CDK1) inhibitor by using palladium-catalyzed C-C bond, C-N bond formation reactions to assemble diverse biheteroaryl molecules led to the unexpected discovery of a pyrazine-pyridine biheteroaryl as a novel series of potent VEGFR-2 inhibitors. Carbon 50-51 kinase insert domain receptor Homo sapiens 273-280 12926963-3 2003 In the first step, Pro-1 acts as a general base to abstract a proton from the third carbon of the substrate, 2-oxo-4-hexenedioate, creating a negative charge on the oxygen at C-2 of this substrate. Carbon 84-90 complement C2 Homo sapiens 175-178 15592926-9 2005 In vivo stimulation of Fugu with LPS and poly I:C showed IL-21 expression to be localised within mucosal tissues. Carbon 48-49 interleukin 21 Homo sapiens 57-62 12926963-4 2003 In the second step, the same hydrogen abstracted by the N-terminal Pro-1 is shuttled back to the fifth carbon of the substrate to form the product, 2-oxo-3-hexenedioate. Carbon 103-109 lamin A/C Homo sapiens 67-72 12902265-3 2003 Overexpression of GDH2 increased ethanol yield from 0.43 to 0.51 mol of carbon (Cmol) Cmol(-1), mainly by reducing xylitol excretion by 44%. Carbon 72-78 glutamate dehydrogenase (NAD(+)) Saccharomyces cerevisiae S288C 18-22 15735068-0 2005 Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides. Carbon 89-95 methylenetetrahydrofolate reductase Homo sapiens 0-35 15735068-1 2005 The methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism is thought to influence the partitioning of 1-carbon units between methylation and other components of 1-carbon metabolism and to influence the risk and etiology of several major cancers and cardiovascular disease. Carbon 119-125 methylenetetrahydrofolate reductase Homo sapiens 4-39 15735068-1 2005 The methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism is thought to influence the partitioning of 1-carbon units between methylation and other components of 1-carbon metabolism and to influence the risk and etiology of several major cancers and cardiovascular disease. Carbon 119-125 methylenetetrahydrofolate reductase Homo sapiens 41-46 15735068-1 2005 The methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism is thought to influence the partitioning of 1-carbon units between methylation and other components of 1-carbon metabolism and to influence the risk and etiology of several major cancers and cardiovascular disease. Carbon 178-184 methylenetetrahydrofolate reductase Homo sapiens 4-39 15735068-1 2005 The methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism is thought to influence the partitioning of 1-carbon units between methylation and other components of 1-carbon metabolism and to influence the risk and etiology of several major cancers and cardiovascular disease. Carbon 178-184 methylenetetrahydrofolate reductase Homo sapiens 41-46 14577667-2 2003 The acyl group at the C-1 position migrates from the anomeric carbon to the C-2 position of the glucuronic acid moiety, producing the aldehyde group at the C-1 position, where the protein easily condenses through a Schiff"s base, in the open-chain aldose form. Carbon 62-68 heterogeneous nuclear ribonucleoprotein C Homo sapiens 22-25 15611094-8 2005 Deletion of ISC1 resulted in markedly lower growth in non-fermentable carbon sources. Carbon 70-76 inositol phosphosphingolipid phospholipase Saccharomyces cerevisiae S288C 12-16 15735051-2 2005 We investigated independent and joint effects of B vitamin intake as well as two polymorphisms of a key one-carbon metabolizing gene [i.e., methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C] on breast cancer risk. Carbon 108-114 methylenetetrahydrofolate reductase Homo sapiens 140-175 15735051-2 2005 We investigated independent and joint effects of B vitamin intake as well as two polymorphisms of a key one-carbon metabolizing gene [i.e., methylenetetrahydrofolate reductase (MTHFR) 677C>T and 1298A>C] on breast cancer risk. Carbon 108-114 methylenetetrahydrofolate reductase Homo sapiens 177-182 14577667-2 2003 The acyl group at the C-1 position migrates from the anomeric carbon to the C-2 position of the glucuronic acid moiety, producing the aldehyde group at the C-1 position, where the protein easily condenses through a Schiff"s base, in the open-chain aldose form. Carbon 62-68 complement C2 Homo sapiens 76-79 14577667-2 2003 The acyl group at the C-1 position migrates from the anomeric carbon to the C-2 position of the glucuronic acid moiety, producing the aldehyde group at the C-1 position, where the protein easily condenses through a Schiff"s base, in the open-chain aldose form. Carbon 62-68 heterogeneous nuclear ribonucleoprotein C Homo sapiens 156-159 12676948-1 2003 ADR1 and CAT8 encode carbon source-responsive transcriptional regulators that cooperatively control expression of genes involved in ethanol utilization. Carbon 21-27 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 9-13 15789748-4 2005 Based on these results, further purification of active components yielded 10 known triterpenoidal saponins, among these compounds, platycodin A, C, D, and deapioplatycodin D exhibited significant inhibitory effects on PL at the concentration of 500 microg/mL with 3.3, 5.2, 34.8, and 11.67% pancreatic lipase activity vs control, respectively. Carbon 145-146 pancreatic lipase Homo sapiens 218-220 15593245-2 2005 Comparing the assignments with those of rapamycin showed that in the published 13C assignments of rapamycin in DMSO-d6 the shifts for C-12 and C-42 have been interchanged, as well as the shifts for C-1 and C-8. Carbon 0-1 CDK5 regulatory subunit associated protein 1 Homo sapiens 143-147 12945913-2 2003 Although this series corresponds to a large modulation in the electrophilic properties of the six-membered ring, all reactions first lead to the quantitative formation of the sigma-adducts C-3a-i, C-5 and C-6 arising from covalent addition of the nucleophile to the C-7 carbon. Carbon 270-276 complement C5 Homo sapiens 197-200 15355973-5 2004 It catalyzes the transfer of the methylene carbon unit to tetrahydrofolate from the methylamine group covalently attached to the lipoamide arm of H-protein. Carbon 43-49 myosin binding protein H Homo sapiens 146-155 12798932-1 2003 Pyruvate kinase (PK) is a key enzyme for the glycolytic pathway and carbon metabolism in general. Carbon 68-74 pyruvate kinase PKLR Oryctolagus cuniculus 0-15 15488475-10 2004 Thus, in our present study, we identified CYP24A1 as the main enzyme responsible for the metabolism of 1alpha,24(R)(OH)2D3 in human keratinocytes, and provided unequivocal evidence to indicate that the multicatalytic enzyme CYP24A1 has the ability to hydroxylate 1alpha,24(R)(OH)2D3 at C-25. Carbon 42-43 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 224-231 15471465-4 2004 The chemo- and regioselectivities are controlled by the enhanced reactivity of the allene unit, while the (Z)-geometry of the exocyclic stannylvinylidene is a consequence of the syn-carbometalation and subsequent reductive elimination from Pd with retention of configuration at the vinyl carbon. Carbon 288-294 synemin Homo sapiens 178-181 12798932-1 2003 Pyruvate kinase (PK) is a key enzyme for the glycolytic pathway and carbon metabolism in general. Carbon 68-74 pyruvate kinase PKLR Oryctolagus cuniculus 17-19 15153069-5 2004 The human COQ2 gene, when expressed in yeast Coq2 null mutant cells, rescued the growth of this yeast strain in the absence of a non-fermentable carbon source and restored CoQ biosynthesis. Carbon 145-151 4-hydroxybenzoate octaprenyltransferase Saccharomyces cerevisiae S288C 45-49 12834847-1 2003 Films of human cytochrome P450 1A2 (cyt P450 1A2) and polystyrene sulfonate were constructed on carbon cloth electrodes using layer-by-layer alternate absorption and evaluated for electrochemical- and H(2)O(2)-driven enzyme-catalyzed oxidation of styrene to styrene oxide. Carbon 96-102 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 15-34 15340085-6 2004 We further identify a second, unexpected role for Pak1 in regulating Snf1-Gal83: the catalytic activity of Pak1 is required for the nuclear enrichment of Snf1-Gal83 in response to carbon stress. Carbon 180-186 serine/threonine protein kinase SAK1 Saccharomyces cerevisiae S288C 50-54 15340085-6 2004 We further identify a second, unexpected role for Pak1 in regulating Snf1-Gal83: the catalytic activity of Pak1 is required for the nuclear enrichment of Snf1-Gal83 in response to carbon stress. Carbon 180-186 Gal83p Saccharomyces cerevisiae S288C 74-79 15340085-6 2004 We further identify a second, unexpected role for Pak1 in regulating Snf1-Gal83: the catalytic activity of Pak1 is required for the nuclear enrichment of Snf1-Gal83 in response to carbon stress. Carbon 180-186 serine/threonine protein kinase SAK1 Saccharomyces cerevisiae S288C 107-111 15340085-6 2004 We further identify a second, unexpected role for Pak1 in regulating Snf1-Gal83: the catalytic activity of Pak1 is required for the nuclear enrichment of Snf1-Gal83 in response to carbon stress. Carbon 180-186 Gal83p Saccharomyces cerevisiae S288C 159-164 12646642-10 2003 In C/S transfectants, actin polymerization induced by membrane IgM ligation was sustained to a greater extent for a longer time compared with wild-type transfectants. Carbon 3-4 actin, beta Gallus gallus 22-27 15388805-7 2004 Overloading of the carbon filter, with a consequent peak release, might explain the high genotoxicity found in water samples C and D. Cell toxicity and DNA damage increases were also detected in metabolically competent HepG2 cells treated with a lower concentration of tap water extract for a longer exposure time (24 h). Carbon 19-25 nuclear RNA export factor 1 Homo sapiens 269-272 12585856-4 2003 This reaction results in high yields and diastereoselectivities and allows the preparation of aminophenols quaternary at the C-1 carbon atom, which cannot be prepared with the methods available till now. Carbon 129-135 heterogeneous nuclear ribonucleoprotein C Homo sapiens 125-128 15137908-2 2004 We show that human erythrocytes also contain FN3K-related protein (FN3K-RP), an enzyme that phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of their sugar moiety. Carbon 175-181 fructosamine 3 kinase related protein Homo sapiens 45-65 15137908-2 2004 We show that human erythrocytes also contain FN3K-related protein (FN3K-RP), an enzyme that phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of their sugar moiety. Carbon 175-181 fructosamine 3 kinase related protein Homo sapiens 67-74 15297675-3 2004 We sequenced three candidate genes (ABCA1, APOA1, and LCAT) that cause Mendelian forms of low HDL-C levels in individuals from a population-based study. Carbon 97-99 lecithin-cholesterol acyltransferase Homo sapiens 54-58 12513977-3 2003 Growth of the strain with a deletion of the ace1 gene on different carbon sources was analyzed. Carbon 67-73 Cup2p Saccharomyces cerevisiae S288C 44-48 15255717-5 2004 Contrary to what we had observed with TEMPO derivatives, we observed two relationships for the plot E(a) vs BDE(C-H), one for the nonpolar released alkyl radicals (E(a) (kJ/mol) = -133.0 + 0.72BDE) and the other one for the polar released alkyl radicals (E(a) (kJ/mol) = -137.0 + 0.69BDE). Carbon 0-1 homeobox D13 Homo sapiens 108-111 15255721-3 2004 Analysis of the (13)C NMR spectrum of the product mixture obtained from the photochemistry of the para isomer selectively deuterated at C3 and C5 (1d(2)()) revealed that the boron-substituted carbon is the active one in the phototransposition reactions in both acetonitrile and TFE. Carbon 192-198 complement C3 Homo sapiens 136-145 15231658-8 2004 However, the G(2)-M arrest induced by C-1305 was greatly prolonged in PARP-1-deficient cells as compared with normal fibroblasts. Carbon 38-39 poly (ADP-ribose) polymerase family, member 1 Mus musculus 70-76 15231658-11 2004 Our data also suggest that the PARP-1 status might be essential for the maintenance of the G(2) arrest induced by C-1305. Carbon 114-115 poly (ADP-ribose) polymerase family, member 1 Mus musculus 31-37 12509487-1 2003 Functional coupling between Ca(2+)-induced Ca(2+) release (CICR) and quantal exocytosis in 5-hydroxytryptamine-loaded INS-1 beta cells was assessed through the use of carbon fibre amperometry in combination with Fura-2. Carbon 167-173 insulin 1 Rattus norvegicus 118-123 15225138-8 2004 This is the first report in any species that adiponectin antagonizes the incorporation of glucose carbon into lipid in the adipocyte, and provides additional evidence that adiponectin acts as an autocrine regulatory factor to regulate energy metabolism. Carbon 98-104 adiponectin, C1Q and collagen domain containing Sus scrofa 45-56 12443781-2 2002 The results support the hypothesis for a subsite within CB1 and CB2 binding domain at the level of the benzylic side chain carbon in the tetrahydrocannabinol and cannabidiol series. Carbon 123-129 cannabinoid receptor 2 Homo sapiens 64-67 15209511-3 2004 Rcd-1 is evolutionarily conserved among many species, and moreover the yeast homologue CAF40 is part of the carbon catabolite repressor protein transcriptional mediator thought to be involved in the negative regulation of genes transcribed by RNA polymerase II. Carbon 108-114 CCR4-NOT core subunit CAF40 Saccharomyces cerevisiae S288C 87-92 15986700-1 2004 Carbon nanofiber/activated carbon fiber (CNF/ACF) composites with multifunctional surfaces were prepared through catalytic growth of CNFs on an ACF. Carbon 0-6 NPHS1 adhesion molecule, nephrin Homo sapiens 41-44 12467423-6 2002 These compounds are reasonably formed by dehydration of unisolated intermediate products 7 and/or 8 obtained by coupling of two molecules through a linkage between the C-2 and the C-3" carbons. Carbon 185-192 complement C2 Homo sapiens 168-171 15986700-1 2004 Carbon nanofiber/activated carbon fiber (CNF/ACF) composites with multifunctional surfaces were prepared through catalytic growth of CNFs on an ACF. Carbon 27-33 NPHS1 adhesion molecule, nephrin Homo sapiens 41-44 14998369-6 2004 In particular, when cells were grown on the non-fermentable carbon source raffinose, respiration is maximally enhanced, and catalase A was efficiently targeted to the mitochondrial matrix where it presumably functions as scavenger of H2O2 and mitochondrial-derived ROS. Carbon 60-66 catalase A Saccharomyces cerevisiae S288C 124-134 12387398-3 2002 A series of normal primary alkanols, dominated by even carbon-numbered homologues from C26 to C32, the secondary alcohol 10-nonacosanol, and some phytosterols are prominent polar compounds in the vegetative detritus source sample. Carbon 55-61 chemokine like factor Homo sapiens 94-97 15099574-4 2004 In this paper, we have used 2D crystals of aquaporin-4 to investigate the effect of a carbon sandwich preparation method on specimen charging. Carbon 86-92 aquaporin 4 Homo sapiens 43-54 15596550-7 2004 The latter reaction, when coupled to ACS, forms a machine for generating acetyl-CoA from CO2 for cell carbon synthesis. Carbon 102-108 phospholipase A2 group XV Canis lupus familiaris 37-40 12161434-7 2002 Stable isotope tracer studies indicate that cSHMT plays an important role in mediating the flux of one-carbon units between dTMP and SAM syntheses. Carbon 103-109 serine hydroxymethyltransferase 1 Homo sapiens 44-49 15113957-7 2004 FOS treatment increased the number of large phagocytic Kupffer cells, as assessed by histological examination of the liver after colloidal carbon injection into the portal vein. Carbon 139-145 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 0-3 15075261-0 2004 Nrg1 and nrg2 transcriptional repressors are differently regulated in response to carbon source. Carbon 82-88 transcriptional regulator NRG1 Saccharomyces cerevisiae S288C 0-4 15075261-2 2004 We show that NRG1 and NRG2 are differently regulated in response to carbon source at both the RNA and protein levels. Carbon 68-74 transcriptional regulator NRG1 Saccharomyces cerevisiae S288C 13-17 15075261-4 2004 Nrg1 protein levels are elevated in response to glucose limitation or growth in nonfermentable carbon sources, whereas Nrg2 levels are diminished. Carbon 95-101 transcriptional regulator NRG1 Saccharomyces cerevisiae S288C 0-4 15075264-1 2004 The Hap4 protein of the budding yeast Saccharomyces cerevisiae activates the transcription of genes that are required for growth on nonfermentable carbon sources. Carbon 147-153 transcription factor HAP4 Saccharomyces cerevisiae S288C 4-8 12161434-8 2002 We conclude that cSHMT has three important functions in the cytoplasm: (1) it preferentially supplies one-carbon units for thymidylate biosynthesis, (2) it depletes methylenetetrahydrofolate pools for SAM synthesis by synthesizing serine, and (3) it sequesters 5-methyltetrahydrofolate and inhibits SAM synthesis. Carbon 106-112 serine hydroxymethyltransferase 1 Homo sapiens 17-22 14998337-5 2004 In addition, when a lactam bridge was used as in H-d-Phe-c[Asp-His-d-Phe-Arg-Trp-Lys]-Thr-NH(2) (7, EC(50) = 0.10 nM), the analogue obtained is as potent as alpha-MSH in the frog skin MC1R assay. Carbon 22-23 proopiomelanocortin Rattus norvegicus 157-166 12140287-5 2002 Recently, carbon starvation has been reported to cause nuclear localization of Gln3 and increased NCR-sensitive transcription. Carbon 10-16 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 79-83 12140287-6 2002 Here we show that nuclear localization of Gln3 during carbon starvation derives from its indirect effects on nitrogen metabolism, i.e. Gln3 does not move into the nucleus of carbon-starved cells if glutamine rather than ammonia is provided as the nitrogen source. Carbon 54-60 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 42-46 12124773-7 2002 On the other hand, for maximal release of bFGF from ECM, the position of the carboxylic group should be three carbons away from the phenol ring. Carbon 110-117 multimerin 1 Homo sapiens 52-55 12221207-2 2002 In liver, methionine availability, both from the diet and via the folate-dependent one-carbon pool, modulates GNMT activity to maintain an optimal SAM:SAH ratio. Carbon 87-93 glycine N-methyltransferase Rattus norvegicus 110-114 12153282-5 2002 Bromo-lithium exchange at carbon atom C-4 and subsequent transmetalation to zinc or tin converted the 4-bromothiazoles 3 into carbon nucleophiles which underwent a second regioselective cross-coupling with another equivalent of 2,4-dibromothiazole (2). Carbon 26-32 complement C4A (Rodgers blood group) Homo sapiens 38-41 12153282-5 2002 Bromo-lithium exchange at carbon atom C-4 and subsequent transmetalation to zinc or tin converted the 4-bromothiazoles 3 into carbon nucleophiles which underwent a second regioselective cross-coupling with another equivalent of 2,4-dibromothiazole (2). Carbon 126-132 complement C4A (Rodgers blood group) Homo sapiens 38-41 12146633-3 2002 The adsorption constant related soil organic carbon content (Koc) calculated from Freundlich equation were 314 for acetochlor, 133 for atrazine, 2805 for carbendazim, 1589 for diazinon, 210 for imidacloprid and 174 for isoproturon. Carbon 45-51 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 61-64 12371743-9 2002 The elongation activity of the mouse Elovl2 was further demonstrated in the transformed mouse L cells incubated with long-chain (C20- and C22-carbon) n-6 and n-3 PUFA substrates by the significant increase in the levels of 24:4n-6 and 24:5n-3, respectively. Carbon 142-148 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 Mus musculus 37-43 12138190-0 2002 A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism. Carbon 112-118 MYC proto-oncogene, bHLH transcription factor Homo sapiens 24-27 12138190-5 2002 SHMT enzymes are the major source of the one-carbon unit required for folate metabolism and for the biosynthesis of nucleotides and amino acids. Carbon 45-51 serine hydroxymethyltransferase 1 Homo sapiens 0-4 12139626-9 2002 Two-hybrid analysis showed that Tot4p also interacts with Cdc19p, suggesting that Tot4p plays an additional role in concert with Cdc19p, perhaps co-ordinating cell growth with carbon source metabolism. Carbon 176-182 Kti12p Saccharomyces cerevisiae S288C 32-37 21748286-7 2011 In human specimens, there was a decrease in occludin and an increase in claudin-1 leading to a significant increase in the C:O ratio in diseased UC colon compared to non-diseased UC colon (P < 0.001) and normal colon (P < 0.01). Carbon 123-124 claudin 1 Homo sapiens 72-81 12139626-9 2002 Two-hybrid analysis showed that Tot4p also interacts with Cdc19p, suggesting that Tot4p plays an additional role in concert with Cdc19p, perhaps co-ordinating cell growth with carbon source metabolism. Carbon 176-182 Kti12p Saccharomyces cerevisiae S288C 82-87 12125049-5 2002 Carbon source-dependent activation mediated by the 265 bp fragment, as well as protein binding to the 30 nt CSRE-like region, is dependent on the presence of CAT8 function, unveiling a complex framework by which the expression of the HAP4 gene is coordinated. Carbon 0-6 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 158-162 21763810-1 2011 An acetylcholinesterase (AChE) purified from maize seedlings was immobilized covalently onto iron oxide nanoparticles (Fe(3)O(4)NP) and carboxylated multi walled carbon nanotubes (c-MWCNT) modified Au electrode. Carbon 162-168 GDSL esterase/lipase ACHE Zea mays 3-23 21763810-1 2011 An acetylcholinesterase (AChE) purified from maize seedlings was immobilized covalently onto iron oxide nanoparticles (Fe(3)O(4)NP) and carboxylated multi walled carbon nanotubes (c-MWCNT) modified Au electrode. Carbon 162-168 GDSL esterase/lipase ACHE Zea mays 25-29 12126417-3 2002 Protonation on oxygen results in nucleophilic attack at the acyl carbon and gives C-2 products. Carbon 65-71 complement C2 Homo sapiens 82-85 21704720-5 2011 These mutations caused deficiency in Adh activity due to loss of the main constitutive isoform of Adh1, as well as alteration of different physiological parameters related to carbon and energy metabolism, including the ability to use ethanol as a carbon source under aerobic conditions; impaired growth under hypoxic conditions with glucose as the carbon source; and diminished production of ethanol in glucose-containing medium. Carbon 247-253 alcohol dehydrogenase 1 Solanum tuberosum 98-102 21704720-5 2011 These mutations caused deficiency in Adh activity due to loss of the main constitutive isoform of Adh1, as well as alteration of different physiological parameters related to carbon and energy metabolism, including the ability to use ethanol as a carbon source under aerobic conditions; impaired growth under hypoxic conditions with glucose as the carbon source; and diminished production of ethanol in glucose-containing medium. Carbon 247-253 alcohol dehydrogenase 1 Solanum tuberosum 98-102 21799342-4 2011 Conditioned medium from control MCF7 cells elevated the RANKL/OPG mRNA ratio in MC3T3-E1 cells; this effect was suppressed by carbon ion irradiation of the MCF7 cells. Carbon 126-132 TNF superfamily member 11 Homo sapiens 56-61 12117615-2 2002 The reactions are regio- and stereoselective; in fact, in the presence of more than one C=O group, the oxido or aziridino functions are formed uniquely at the C=O of C-17 (or C-20 depending on its position in the starting molecule), and the C-20(R) stereoisomer is often the only product isolated. Carbon 88-89 cytokine like 1 Homo sapiens 166-170 21799342-4 2011 Conditioned medium from control MCF7 cells elevated the RANKL/OPG mRNA ratio in MC3T3-E1 cells; this effect was suppressed by carbon ion irradiation of the MCF7 cells. Carbon 126-132 basic transcription factor 3 pseudogene 11 Homo sapiens 62-65 12117615-2 2002 The reactions are regio- and stereoselective; in fact, in the presence of more than one C=O group, the oxido or aziridino functions are formed uniquely at the C=O of C-17 (or C-20 depending on its position in the starting molecule), and the C-20(R) stereoisomer is often the only product isolated. Carbon 159-160 cytokine like 1 Homo sapiens 166-170 12076151-4 2002 All these molecules contain a quaternary stereogenic carbon at C-1 or C-3 of the cyclopropane ring and bear an amino, a hydroxymethyl, or a methyl group as an additional substituent. Carbon 53-59 heterogeneous nuclear ribonucleoprotein C Homo sapiens 63-73 12033881-2 2002 1-Phenyl-4-p-tolyl-1,3-butadiyne, (13)C-enriched at C-1, was synthesized and subjected to flash vacuum pyrolysis. Carbon 38-39 heterogeneous nuclear ribonucleoprotein C Homo sapiens 52-55 11992258-3 2002 Individuals with ABCD1 mutations accumulate very-long-chain fatty acids (VLCFA) (carbon length >22). Carbon 81-87 ATP binding cassette subfamily D member 1 Homo sapiens 17-22 12146911-15 2002 An acid hydrolysis mechanism was proposed for the formation of As(254) from each of the native arsenosugars by hydrolysis at the C-1 carbon on the ribose ring. Carbon 133-139 heterogeneous nuclear ribonucleoprotein C Homo sapiens 129-132 12059964-5 2002 In addition, the molecular-feature domains and their polarities (spatial shifts of responses with an increase in carbon chain length) that were defined by the optical imaging method could be also detected by the Zif268 mapping method. Carbon 113-119 early growth response 1 Mus musculus 212-218 11976968-9 2002 Under culture conditions that induce heat shock, conidiation, and carbon starvation, expression of the gsn gene was decreased, and glycogen synthase activity and glycogen content behaved similarly. Carbon 66-72 gelsolin Homo sapiens 103-106 11941464-4 2002 In contrast, there was evidence that anaplerotic carbon flow was stimulated in the transformed lines with less than 60% Fd-GOGAT, since phospho enolpyruvate carboxylase (PEPc) activity and (PEPc) protein were increased. Carbon 49-55 phosphoenolpyruvate carboxylase Nicotiana tabacum 170-174 11941464-4 2002 In contrast, there was evidence that anaplerotic carbon flow was stimulated in the transformed lines with less than 60% Fd-GOGAT, since phospho enolpyruvate carboxylase (PEPc) activity and (PEPc) protein were increased. Carbon 49-55 phosphoenolpyruvate carboxylase Nicotiana tabacum 190-194 15046341-8 2004 Experiments with radiolabeled RDX indicate that 90% of the carbon end products remained in solution and that negligible mineralization occurred. Carbon 59-65 radixin Homo sapiens 30-33 11871877-2 2002 Transition structure 1-TS computed at the MP2(fc)/6-31G(d) level of theory revealed that the reaction proceeds through a late transition state with considerably pronounced double bond participation and a substantially cleaved C-Cl bond. Carbon 226-227 tryptase pseudogene 1 Homo sapiens 42-45 11887874-3 2002 Resulting organic carbon/water partition coefficients (log Koc) were related to suspended sediment concentration and ranged from 2.28 to 5.20 for diuron; and from 2.41 to 4.89 for Irgarol 1051. Carbon 18-24 insulin like growth factor 2 mRNA binding protein 3 Homo sapiens 59-62 14975647-3 2004 By an accumulation energy of 50 kJL(-1) the synergetic effect of 0.2 gL(-1)TiO(2) P-25 with hydrogen peroxide (H(2)O(2)) and Na(2)S(2)O(8) leads to a 55% and 73% reduction of the initial organic carbon content, respectively. Carbon 195-201 tubulin polymerization promoting protein Homo sapiens 82-86 11927259-3 2002 Here we employ atomic-force microscopy (AFM) with carbon nanotube probes to image search intermediates of human 8-oxoguanine DNA glycosylase (hOGG1) scanning DNA. Carbon 50-56 8-oxoguanine DNA glycosylase Homo sapiens 112-140 11927259-3 2002 Here we employ atomic-force microscopy (AFM) with carbon nanotube probes to image search intermediates of human 8-oxoguanine DNA glycosylase (hOGG1) scanning DNA. Carbon 50-56 8-oxoguanine DNA glycosylase Homo sapiens 142-147 12702322-2 2002 In previous studies we have found that the genes encoding the unique components of this complex (GCV1, GCV2 and GCV3) are regulated by the one-carbon status of the cell. Carbon 143-149 glycine decarboxylase subunit P Saccharomyces cerevisiae S288C 103-107 11844113-9 2002 These results suggest that SAMS3 has a different function(s) in one carbon metabolism relative to the other members of the SAMS gene family. Carbon 68-74 S-adenosylmethionine synthetase family protein Arabidopsis thaliana 27-32 12572994-6 2002 The maintenance of an (S)-configured C-4 carbon is optimal in the design of desferrithiocin-based iron chelators. Carbon 41-47 complement C4A (Rodgers blood group) Homo sapiens 37-40 11786345-1 2002 Cholinesterase sensors based on glassy carbon and planar epoxy graphite electrodes modified with processed polyaniline have been developed and examined for pesticide detection. Carbon 39-45 butyrylcholinesterase Homo sapiens 0-14 12382754-3 2002 The dosemeter uses LiF powder, which is deposited onto the adhesive face of a carbon-loaded Kapton tape. Carbon 78-84 LIF interleukin 6 family cytokine Homo sapiens 19-22 11724580-7 2001 The deficiency in RPA in extracts from cells treated with low levels of C-1027 can be fully complemented by the addition of exogenous RPA, and may be due to a C-1027-induced decrease in the extractability of RPA. Carbon 72-73 replication protein A1 Homo sapiens 18-21 11724580-7 2001 The deficiency in RPA in extracts from cells treated with low levels of C-1027 can be fully complemented by the addition of exogenous RPA, and may be due to a C-1027-induced decrease in the extractability of RPA. Carbon 72-73 replication protein A1 Homo sapiens 134-137 11724580-7 2001 The deficiency in RPA in extracts from cells treated with low levels of C-1027 can be fully complemented by the addition of exogenous RPA, and may be due to a C-1027-induced decrease in the extractability of RPA. Carbon 72-73 replication protein A1 Homo sapiens 134-137 11516159-1 2001 The role of cytosolic and mitochondrial serine hydroxymethyltransferase in supplying one-carbon groups for purine and thymidylate biosynthesis in MCF-7 cells was investigated by observing folate-mediated one-carbon metabolism of l-[3-(13)C]serine, [2-(13)C]glycine, and [(13)C]formate. Carbon 89-95 serine hydroxymethyltransferase 1 Homo sapiens 12-71 11442413-4 2001 Stereoselective construction of a quaternary carbon at C-4 was achieved by alpha-alkylation of the cyano group and conversion of the sterically hindered cyano group to a methyl group via our novel reaction for conversion of primary aliphatic amines into alcohols. Carbon 45-51 complement C4A (Rodgers blood group) Homo sapiens 55-58 11448685-4 2001 The data, correlated with previous literature results, clearly show that at pH 2.5 the production of carbon dioxide from C-6 and C-1 carbon atoms is nearly equivalent. Carbon 101-107 heterogeneous nuclear ribonucleoprotein C Homo sapiens 129-132 21571106-1 2011 The objective of the present in vitro research was to investigate cardiac tissue cell functions (specifically cardiomyocytes and neurons) on poly(lactic-co-glycolic acid) (PLGA) (50:50 wt.%)-carbon nanofiber (CNF) composites to ascertain their potential for myocardial tissue engineering applications. Carbon 191-197 NPHS1 adhesion molecule, nephrin Homo sapiens 209-212 11401707-1 2001 Saccharomyces cerevisiae CYC1 gene expression has been studied in great detail with regard to the response to oxygen availability and carbon source. Carbon 134-140 cytochrome c isoform 1 Saccharomyces cerevisiae S288C 25-29 21438710-5 2011 Non-polar four carbon atoms chains, linear or branched, dramatically diminished the affinity and selectivity towards LDH-C4. Carbon 15-21 lactate dehydrogenase C Mus musculus 117-123 11405098-0 2001 Contribution of Cat8 and Sip4 to the transcriptional activation of yeast gluconeogenic genes by carbon source-responsive elements. Carbon 96-102 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 16-20 21756372-0 2011 Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation. Carbon 84-90 proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) Mus musculus 61-68 11178840-1 2001 [reaction: see text] The first total synthesis of (+/-)-scopadulin was accomplished by a stereoselective construction of a quaternary carbon at C-4, conversion of the hindered cyano group to a methyl group via our novel reaction for conversion of primary aliphatic amines into alcohols, and a highly chemo- and stereoselective methylation at C-16. Carbon 134-140 complement C4A (Rodgers blood group) Homo sapiens 144-147 21507984-5 2011 We also found that RV and poly(I:C) each stimulated Rac1 activation, reactive oxygen species (ROS) generation, and Rac1-dependent NADPH oxidase 1 (NOX1) activity. Carbon 33-34 Rac family small GTPase 1 Homo sapiens 52-56 21507984-5 2011 We also found that RV and poly(I:C) each stimulated Rac1 activation, reactive oxygen species (ROS) generation, and Rac1-dependent NADPH oxidase 1 (NOX1) activity. Carbon 33-34 Rac family small GTPase 1 Homo sapiens 115-119 11157256-9 2001 Northern analyses indicated increases in the transcript levels of cmg1 due to both carbon starvation and the presence of ground sclerotia of S. sclerotiorum; only slight repression was observed in the presence of 2% glucose. Carbon 83-89 Cmg1p Saccharomyces cerevisiae S288C 66-70 21644568-2 2011 This method enables preparation of a variety of isoindolinones with substitution on the benzoyl fragment and C-3 carbon. Carbon 113-119 complement C3 Homo sapiens 109-112 21721654-0 2011 Spin transport properties of single metallocene molecules attached to single-walled carbon nanotubes via nickel adatoms. Carbon 84-90 spindlin 1 Homo sapiens 0-4 11180457-5 2001 We found that expression of various genes involved in carbon metabolism are affected by the mutation and that among them, UGP1 promoter activity was increased in the absence of Pho85 kinase. Carbon 54-60 UTP glucose-1-phosphate uridylyltransferase Saccharomyces cerevisiae S288C 122-126 21682510-2 2011 Plots of the C-Hal bond-length change versus the corresponding vibrational frequency shift of the C-Hal stretch all give straight lines. Carbon 98-99 histidine ammonia-lyase Homo sapiens 100-103 21682510-3 2011 The coefficients of determination range from 0.94366 to 0.99219, showing that the correlation between the C-Hal bond-length change and the corresponding frequency shift is very good in the halogen-bonded complexes. Carbon 106-107 histidine ammonia-lyase Homo sapiens 108-111 11162492-7 2001 Our results allow us to define Mig1p as a new factor probably contributing to the carbon source-dependent transcription regulation of HXK2 gene. Carbon 82-88 vacuolar protein sorting 4 homolog B Homo sapiens 31-36 11024040-0 2001 The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. Carbon 90-96 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 30-35 21470075-11 2011 In contrast, the hippocampal NR2A and NR2B levels significantly decreased in the NCR group compared with the C group (P < 0.05). Carbon 82-83 glutamate ionotropic receptor NMDA type subunit 2B Rattus norvegicus 38-42 21332506-10 2011 Central clock functions that depend on CCA1/LHY are required to set an appropriate rate of starch degradation and maintain a supply of carbon to support growth through to dawn, whereas ELF3 acts to decrease growth in the light period and promote growth in the night. Carbon 135-141 Homeodomain-like superfamily protein Arabidopsis thaliana 44-47 11134339-12 2001 Altogether, these results suggest that Zds1-mediated cytoplasmic localization of Bcy1 is regulated by carbon source-dependent phosphorylation of cluster II serines, while cluster I acts in a Zds1-independent manner. Carbon 102-108 Zds1p Saccharomyces cerevisiae S288C 39-43 11134339-12 2001 Altogether, these results suggest that Zds1-mediated cytoplasmic localization of Bcy1 is regulated by carbon source-dependent phosphorylation of cluster II serines, while cluster I acts in a Zds1-independent manner. Carbon 102-108 cAMP-dependent protein kinase regulatory subunit BCY1 Saccharomyces cerevisiae S288C 81-85 10990457-5 2000 The sip1Delta sip2Delta gal83Delta strain is unable to derepress invertase, grows poorly on alternative carbon sources and fails to direct the phosphorylation of the Mig1 and Sip4 proteins in vivo. Carbon 104-110 gem nuclear organelle associated protein 2 Homo sapiens 4-13 21593791-0 2011 A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt-TSC2-mTOR signaling. Carbon 31-37 TSC complex subunit 2 Homo sapiens 109-113 21500305-6 2011 Consistently, it reacts with simple inorganic and organic molecules to form GeF(3)(+)-L complexes (L = H(2)O, NH(3), C(2)H(2), C(2)H(4), C(6)H(6), CO(2), SO(2) and GeF(4)). Carbon 0-1 Rho guanine nucleotide exchange factor 4 Homo sapiens 164-170 21464327-4 2011 We present carbon isotope data from 452 fossil teeth that record differential rates of diet change from C(3) to mixed C(3)/C(4) or C(4) diets among East African herbivore families at seven different time periods during the Late Miocene to the Pliocene (9.9-3.2 Ma). Carbon 11-17 complement C3 Homo sapiens 104-108 21464327-4 2011 We present carbon isotope data from 452 fossil teeth that record differential rates of diet change from C(3) to mixed C(3)/C(4) or C(4) diets among East African herbivore families at seven different time periods during the Late Miocene to the Pliocene (9.9-3.2 Ma). Carbon 11-17 complement C3 Homo sapiens 118-122 10940042-2 2000 The gcr1 mutant of yeast grows at near wild-type rates on nonfermentable carbon sources but exhibits a severe growth defect when grown in the presence of glucose, even when nonfermentable carbon sources are available. Carbon 73-79 transcription regulator GCR1 Saccharomyces cerevisiae S288C 4-8 21392959-0 2011 CdS nanoparticles functionalized colloidal carbon particles: preparation, characterization and application for electrochemical detection of thrombin. Carbon 43-49 coagulation factor II, thrombin Bos taurus 140-148 10940042-2 2000 The gcr1 mutant of yeast grows at near wild-type rates on nonfermentable carbon sources but exhibits a severe growth defect when grown in the presence of glucose, even when nonfermentable carbon sources are available. Carbon 188-194 transcription regulator GCR1 Saccharomyces cerevisiae S288C 4-8 21366255-5 2011 Density functional theory estimates of rate and equilibrium constants show that the kinetically relevant O(2) activation steps involve direct O(2)* (or O(2)) reactions with CO* to form reactive O*-O-C*=O intermediates that decompose to form CO(2) and chemisorbed O*, instead of unassisted activation steps involving molecular adsorption and subsequent dissociation of O(2). Carbon 173-174 immunoglobulin kappa variable 1D-39 Homo sapiens 105-109 21366255-5 2011 Density functional theory estimates of rate and equilibrium constants show that the kinetically relevant O(2) activation steps involve direct O(2)* (or O(2)) reactions with CO* to form reactive O*-O-C*=O intermediates that decompose to form CO(2) and chemisorbed O*, instead of unassisted activation steps involving molecular adsorption and subsequent dissociation of O(2). Carbon 173-174 immunoglobulin kappa variable 1D-39 Homo sapiens 142-146 10990433-2 2000 This protocol couples a glycal epoxidation reaction with a C-2 alkoxy-directed carbon-carbon bond-forming reaction. Carbon 79-85 complement C2 Homo sapiens 59-62 21366255-5 2011 Density functional theory estimates of rate and equilibrium constants show that the kinetically relevant O(2) activation steps involve direct O(2)* (or O(2)) reactions with CO* to form reactive O*-O-C*=O intermediates that decompose to form CO(2) and chemisorbed O*, instead of unassisted activation steps involving molecular adsorption and subsequent dissociation of O(2). Carbon 173-174 immunoglobulin kappa variable 1D-39 Homo sapiens 142-146 21366255-5 2011 Density functional theory estimates of rate and equilibrium constants show that the kinetically relevant O(2) activation steps involve direct O(2)* (or O(2)) reactions with CO* to form reactive O*-O-C*=O intermediates that decompose to form CO(2) and chemisorbed O*, instead of unassisted activation steps involving molecular adsorption and subsequent dissociation of O(2). Carbon 173-174 immunoglobulin kappa variable 1D-39 Homo sapiens 142-146 10990433-2 2000 This protocol couples a glycal epoxidation reaction with a C-2 alkoxy-directed carbon-carbon bond-forming reaction. Carbon 86-92 complement C2 Homo sapiens 59-62 10801792-1 2000 The proposed rate-limiting step of the glyoxalase I catalyzed reaction is the proton abstraction from the C1 carbon of the substrate by Glu(172). Carbon 109-115 glyoxalase I Homo sapiens 39-51 21240422-1 2011 Tyrosinase has been immobilized on a Au nanoparticles encapsulated-dendrimer bonded conducting polymer on a glassy carbon electrode for the estimation of catechol. Carbon 115-121 tyrosinase Homo sapiens 0-10 10887204-1 2000 Dopamine-beta-hydroxylase (DbetaH) is a copper-containing enzyme that uses molecular oxygen and ascorbate to catalyze the addition of a hydroxyl group on the beta-carbon of dopamine to form norepinephrine. Carbon 163-169 dopamine beta-hydroxylase Homo sapiens 0-25 21491330-1 2011 We have synthesized a carbon linker analogue of INA (oligonucleotides containing insertions of 1-O-(1-pyrenylmethyl)glycerol). Carbon 22-28 internexin neuronal intermediate filament protein alpha Homo sapiens 48-51 21233333-5 2011 The observed cellular defects in roots of atdfb underscore the essential role of folylpolyglutamates in the highly compartmentalized one-carbon transfer reactions (C1 metabolism) that lead to the biosynthesis of compounds required for metabolically active cells found in the growing root apex. Carbon 137-143 DHFS-FPGS homolog B Arabidopsis thaliana 42-47 21238729-3 2011 The CNFs, which were prepared by electrospinning technique and subsequent thermal treatment, were used to modify carbon paste electrode (CNF-CPE) to construct the amperometric sensor device without any oxidation pretreatment. Carbon 113-119 NPHS1 adhesion molecule, nephrin Homo sapiens 4-7 16228610-2 2004 The following functions have been proposed for these pathways: adjustment of ATP/NADPH ratio required for CO(2) fixation, generation of the proton gradient for the down-regulation of Photosystem II (PS II), and ATP supply the active transport of inorganic carbon in algal cells. Carbon 256-262 2,4-dienoyl-CoA reductase 1 Homo sapiens 81-86 10887204-1 2000 Dopamine-beta-hydroxylase (DbetaH) is a copper-containing enzyme that uses molecular oxygen and ascorbate to catalyze the addition of a hydroxyl group on the beta-carbon of dopamine to form norepinephrine. Carbon 163-169 dopamine beta-hydroxylase Homo sapiens 27-33 15150827-5 2004 Oxidized free sn-2 fatty acids and intact GPC-DMPO adducts correspond to carbon- and oxygen-centered radicals that were identified by MS/MS as alkyl, hydroxy-alkyl, alkoxyl, hydroxy-alkoxyl, peroxyl and hydroperoxide-alkoxyl spin adducts. Carbon 73-79 glycophorin C (Gerbich blood group) Homo sapiens 42-45 10773444-4 2000 Although these constructs have proved to work well for most purposes, they have certain limitations: (1) they give significant and carbon-source-dependent lacZ background expression; (2) unlike most other yeast promoters, the CYC1 upstream region has a partially open chromatin structure with an accessible TATA box; (3) they use only a single, moderately sensitive reporter; and (4) the use of multicopy vectors can result in activator titration. Carbon 131-137 cytochrome c isoform 1 Saccharomyces cerevisiae S288C 226-230 12855560-6 2003 C-18 bound directly to human CCR5, and this interaction was partially competed by the beta-chemokine macrophage inflammatory protein 1 beta (MIP-1 beta) and by HIV-1 R5 gp120. Carbon 0-1 C-C motif chemokine receptor 5 Homo sapiens 29-33 14641596-9 2003 Pore water and rock geochemical analyses suggest that these SRB"s may have been sustained by sulphate diffusing from the adjacent U-rich, Carbon Leader where it was formed by radiolysis of sulphide. Carbon 138-144 chaperonin containing TCP1 subunit 4 Homo sapiens 60-63 21522316-1 2011 In the title compound, C(9)H(10)ClNO(3)S, the amide H atom is syn with respect to the ortho-methyl group in the benzene ring and the C-S-N-C torsion angle is -66.9 (2) . Carbon 23-24 synemin Homo sapiens 62-65 21522316-1 2011 In the title compound, C(9)H(10)ClNO(3)S, the amide H atom is syn with respect to the ortho-methyl group in the benzene ring and the C-S-N-C torsion angle is -66.9 (2) . Carbon 32-33 synemin Homo sapiens 62-65 21123458-0 2011 MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. Carbon 63-69 methylenetetrahydrofolate reductase Homo sapiens 0-5 10747808-1 2000 Biotin synthase and lipoate synthase are homodimers that are required for the C-S bond formation at nonactivated carbon in the biosynthesis of biotin and lipoic acid, respectively. Carbon 78-79 lipoic acid synthetase Homo sapiens 20-36 21178087-1 2011 The enzymes serine hydroxymethyltransferase 1 (gene name SHMT1) and methylenetetrahydrofolate reductase (gene name MTHFR) regulate key reactions in folate-mediated one-carbon metabolism. Carbon 168-174 methylenetetrahydrofolate reductase Homo sapiens 68-103 21178087-1 2011 The enzymes serine hydroxymethyltransferase 1 (gene name SHMT1) and methylenetetrahydrofolate reductase (gene name MTHFR) regulate key reactions in folate-mediated one-carbon metabolism. Carbon 168-174 methylenetetrahydrofolate reductase Homo sapiens 115-120 14599021-6 2003 The effect of 7-OH deprotonation yields a high frequency shift of 7-8 ppm on the C-7 carbon atom of the piperazine complex whereas it is as large as 12 ppm in the morpholine complex in the solid. Carbon 85-91 complement C7 Homo sapiens 81-84 12676948-7 2003 ADR1-dependent genes fall into a variety of functional classes with carbon metabolism containing the largest number of members. Carbon 68-74 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 0-4 10747808-1 2000 Biotin synthase and lipoate synthase are homodimers that are required for the C-S bond formation at nonactivated carbon in the biosynthesis of biotin and lipoic acid, respectively. Carbon 113-119 lipoic acid synthetase Homo sapiens 20-36 12826254-0 2003 Identification of spin trapped carbon-centered radicals in soybean lipoxygenase-dependent peroxidations of omega-3 polyunsaturated fatty acids by LC/ESR, LC/MS, and tandem MS. With the combined techniques of on-line liquid chromatography/electron spin resonance (LC/ESR) and on-line liquid chromatography/mass spectrometry (LC/MS), we have previously characterized all classes of lipid-derived carbon-centered radicals (*Ld) formed from omega-6 polyunsaturated fatty acids (PUFAs: linoleic acid and arachidonic acid). Carbon 31-37 linoleate 9S-lipoxygenase-4 Glycine max 67-79 21107868-6 2011 We found that the essential PUFA were transferred from the producers to the primary consumers with about twice higher efficiency than bulk carbon. Carbon 139-145 pumilio RNA binding family member 3 Homo sapiens 28-32 12826254-1 2003 In the present study, the carbon-centered radicals formed from two omega-3 PUFAs (linolenic acid and docosahexaenoic acid) resulting from their reactions with soybean lipoxygenase in the presence of alpha-[4-pyridyl 1-oxide]-N-tert-butylnitrone (POBN) were investigated using the combination of LC/ESR and LC/MS techniques. Carbon 26-32 linoleate 9S-lipoxygenase-4 Glycine max 167-179 10759515-5 2000 The Calvin cycle intermediates fructose-1,6-bisphosphate and ribulose-1, 5-bisphosphate exerted an inhibitory effect on PGM activity, supporting its proposed involvement in controlling photosynthetic carbon flow. Carbon 200-206 phosphoglucomutase Arabidopsis thaliana 120-123 21247457-1 2011 BACKGROUND: Several genetic variants in the ATP-binding cassette transporter A1 (ABCA1) gene have associated with modifications of serum high-density lipoprotein cholesterol (HDL-C) levels and the susceptibility for coronary heart disease, but the findings are still controversial in diverse racial/ethnic groups. Carbon 178-180 ATP binding cassette subfamily A member 1 Homo sapiens 44-79 21247457-1 2011 BACKGROUND: Several genetic variants in the ATP-binding cassette transporter A1 (ABCA1) gene have associated with modifications of serum high-density lipoprotein cholesterol (HDL-C) levels and the susceptibility for coronary heart disease, but the findings are still controversial in diverse racial/ethnic groups. Carbon 178-180 ATP binding cassette subfamily A member 1 Homo sapiens 81-86 12754263-11 2003 These results demonstrate that (i) exogenously supplied glucose can replace the function of photoassimilates in roots; (ii) APR is subject to co-ordinated metabolic control by carbon metabolism; (iii) positive sugar signalling overrides negative signalling from nitrate assimilation in APR regulation. Carbon 176-182 APS reductase 1 Arabidopsis thaliana 124-127 10759515-9 2000 Our results indicate that plastidic PGM is an important factor affecting carbon flux in triacylglycerol accumulation in oilseed plants, most likely through its essential role in starch synthesis. Carbon 73-79 phosphoglucomutase Arabidopsis thaliana 36-39 12754263-12 2003 Furthermore, signals originating from nitrogen and carbon metabolism regulate APR synergistically. Carbon 51-57 APS reductase 1 Arabidopsis thaliana 78-81 10677586-9 2000 Although earlier extensive structure-activity studies of vitamin D analogues showed stereochemistry at the C-1, C-3, and C-20 of 1alpha,25(OH)(2)D(3) to be the key structural motif for vitamin D action, our results clearly demonstrated that stereochemistry at the C-2 is also an important structural motif for vitamin D action and imply that 2-methyl substitution possibly induces conformational changes in ring A depending upon the combinations of configurations of the C-1 and C-3 hydroxyl groups with C-20 stereochemistry. Carbon 107-108 complement C2 Homo sapiens 121-124 20859794-4 2011 The specificity and potency of these compounds for blocking PDE action have been improved by appending groups at positions on the rings as well as by modification of the number and distribution of nitrogens and carbons in those rings. Carbon 211-218 aldehyde dehydrogenase 7 family member A1 Homo sapiens 60-63 22066229-0 2011 Tyrosinase-modified carbon felt-based flow-biosensors: the role of ultra-sonication in shortening the enzyme immobilization time and improving the sensitivity for p-chlorophenol. Carbon 20-26 tyrosinase Homo sapiens 0-10 22066229-1 2011 Tyrosinase (TYR) was covalently immobilized onto amino-functionalized carbon felt surface via glutaraldehyde-coupling under ultrasonic treatment for 10 min. Carbon 70-76 tyrosinase Homo sapiens 0-10 22066229-1 2011 Tyrosinase (TYR) was covalently immobilized onto amino-functionalized carbon felt surface via glutaraldehyde-coupling under ultrasonic treatment for 10 min. Carbon 70-76 tyrosinase Homo sapiens 12-15 22066229-2 2011 The resulting TYR-immobilized carbon felt was used as a working electrode unit of bioelectrocatalytic flow-through detector for TYR substrates (catechol, p-chlorophenol (p-CP), p-cresol, phenol etc.). Carbon 30-36 tyrosinase Homo sapiens 14-17 22066229-2 2011 The resulting TYR-immobilized carbon felt was used as a working electrode unit of bioelectrocatalytic flow-through detector for TYR substrates (catechol, p-chlorophenol (p-CP), p-cresol, phenol etc.). Carbon 30-36 tyrosinase Homo sapiens 128-131 22066229-4 2011 Compared with previous work in which TYR was immobilized onto amino-functionalized carbon felt for 16 hr without the ultrasonic treatment, we succeeded in (1) shortening the enzyme immobilization time from 16 hr to 10 min, (2) enhancing the sensitivity of p-CP, and (3) improving the operational stability of p-CP. Carbon 83-89 tyrosinase Homo sapiens 37-40 22066229-5 2011 The ultrasonic treatment during the TYR immobilization step would lead to certain changes in the structure of the immobilized TYR and the morphology of the immobilized TYR-layer on the carbon felt surface. Carbon 185-191 tyrosinase Homo sapiens 36-39 21182415-3 2011 Two key focus areas of the C-CCNE are, first, the selective delivery of drugs and imaging agents utilizing advanced nanoparticle technology, and second, novel approaches to imaging and radiotherapy utilizing carbon nanotube-based x-ray sources. Carbon 208-214 cyclin E1 Homo sapiens 29-33 21980405-3 2011 MTHFR is a key regulator of the intracellular one-carbon milieu, including DNA methylation, and each copy of the 677T allele reduces MTHFR activity by 35%. Carbon 50-56 methylenetetrahydrofolate reductase Homo sapiens 0-5 21980405-3 2011 MTHFR is a key regulator of the intracellular one-carbon milieu, including DNA methylation, and each copy of the 677T allele reduces MTHFR activity by 35%. Carbon 50-56 methylenetetrahydrofolate reductase Homo sapiens 133-138 22163924-1 2011 The effects of different aluminum species on malate dehydrogenase (MDH) activity were investigated by monitoring amperometric i-t curves for the oxidation of NADH at low overpotential using a functionalized multi-wall nanotube (MWNT) modified glass carbon electrode (GCE). Carbon 249-255 malic enzyme 1 Homo sapiens 45-65 22163924-1 2011 The effects of different aluminum species on malate dehydrogenase (MDH) activity were investigated by monitoring amperometric i-t curves for the oxidation of NADH at low overpotential using a functionalized multi-wall nanotube (MWNT) modified glass carbon electrode (GCE). Carbon 249-255 malic enzyme 1 Homo sapiens 67-70 20952580-0 2010 Hal4 and Hal5 protein kinases are required for general control of carbon and nitrogen uptake and metabolism. Carbon 66-72 serine/threonine protein kinase SAT4 Saccharomyces cerevisiae S288C 0-4 20952580-0 2010 Hal4 and Hal5 protein kinases are required for general control of carbon and nitrogen uptake and metabolism. Carbon 66-72 protein kinase HAL5 Saccharomyces cerevisiae S288C 9-13 20952580-9 2010 These results indicate that the hal4 hal5 mutant presents defects in the general control of nitrogen and carbon metabolism, which correlate with reduced transport of amino acids and glucose, respectively. Carbon 105-111 serine/threonine protein kinase SAT4 Saccharomyces cerevisiae S288C 32-36 20952580-9 2010 These results indicate that the hal4 hal5 mutant presents defects in the general control of nitrogen and carbon metabolism, which correlate with reduced transport of amino acids and glucose, respectively. Carbon 105-111 protein kinase HAL5 Saccharomyces cerevisiae S288C 37-41 20692813-1 2010 Methylenetetrahydrofolate reductase (MTHFR) is a critical molecule for single-carbon transfer reactions. Carbon 78-84 methylenetetrahydrofolate reductase Homo sapiens 0-35 20692813-1 2010 Methylenetetrahydrofolate reductase (MTHFR) is a critical molecule for single-carbon transfer reactions. Carbon 78-84 methylenetetrahydrofolate reductase Homo sapiens 37-42 21043511-3 2010 The first step, the copper-, ascorbate-, and O(2)-dependent stereospecific hydroxylation at the alpha-carbon of the C-terminal glycine, is catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM). Carbon 102-108 peptidylglycine alpha-amidating monooxygenase Homo sapiens 152-201 21043511-3 2010 The first step, the copper-, ascorbate-, and O(2)-dependent stereospecific hydroxylation at the alpha-carbon of the C-terminal glycine, is catalyzed by peptidylglycine alpha-hydroxylating monooxygenase (PHM). Carbon 102-108 peptidylglycine alpha-amidating monooxygenase Homo sapiens 203-206 20648536-6 2010 Rockwell C indentation and dynamic scratch testing on 2-10 mum thick ta-C films on Co28Cr6Mo substrates showed excellent adhesion with HF1 grade and up to 48 N for the critical load L(C2) during scratch testing. Carbon 9-10 complement factor H Homo sapiens 135-138 20876337-10 2010 Overall, a central yet complex role for mMDH emerges in the partitioning of carbon and energy in leaves, providing new directions for bioengineering of plant growth rate and a new insight into the molecular mechanisms linking respiration and photosynthesis in plants. Carbon 76-82 malate dehydrogenase 2, NAD (mitochondrial) Mus musculus 40-44 21588864-1 2010 In the title complex, [Ca(C(10)H(6)NO(2))(2)(H(2)O)(2)](n), the Ca(II) ion is eight-coordinated by six carboxyl-ate O atoms from four separate quinoline-3-carboxyl-ate ligands, two of which are bidentate chelate and two bridging, and two water mol-ecules in a distorted square-anti-prismatic geometry. Carbon 23-24 carbonic anhydrase 2 Homo sapiens 64-70 20854852-7 2010 In this study, S. cerevisiae using glycerol as substrate was modified through one-step gene disruption for redirection of glycerol carbon flux into ethanol by the deletion of two glycerol production genes, FPS1 and GPD2. Carbon 131-137 Fps1p Saccharomyces cerevisiae S288C 206-210 20849119-0 2010 Direct carbon-carbon bond formation via reductive soft enolization: a kinetically controlled syn-aldol addition of alpha-halo thioesters and enolizable aldehydes. Carbon 7-13 synemin Homo sapiens 93-96 20849119-0 2010 Direct carbon-carbon bond formation via reductive soft enolization: a kinetically controlled syn-aldol addition of alpha-halo thioesters and enolizable aldehydes. Carbon 14-20 synemin Homo sapiens 93-96 20552676-2 2010 5,10-Methylenetetrahydrofolate reductase (MTHFR) is a crucial enzyme in folate-mediated one-carbon metabolism and folate deficiency can be associated with psychiatric symptoms. Carbon 92-98 methylenetetrahydrofolate reductase Homo sapiens 0-40 20652542-2 2010 Here we report a simple but functional and stable enzyme-electrode system based on a glassy carbon (GC) electrode with human flavin-containing monooxygenase isoform 3 (hFMO3) entrapped in a gel cross-linked with bovine serum albumin (BSA) by glutaraldehyde. Carbon 92-98 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 168-173 20660228-0 2010 Light and low-CO2-dependent LCIB-LCIC complex localization in the chloroplast supports the carbon-concentrating mechanism in Chlamydomonas reinhardtii. Carbon 91-97 uncharacterized protein Chlamydomonas reinhardtii 28-32 21253464-5 2010 The mutant strains aim45 and yor356w/cir2 displayed better growth on several non-fermentable carbon sources, which depended on the component of the electron transport chain that accepts the electrons resulting from its mitochondrial oxidation. Carbon 93-99 putative electron-transferring-flavoprotein dehydrogenase Saccharomyces cerevisiae S288C 37-41 21253464-7 2010 Other phenotypes identified suggest that AIM45, YGR207c/CIR1 and YOR356w/CIR2 can protect cells from oxidative and heat stress, which encompass increased heat stress sensitivity, superoxide sensitivity, both only on non-fermentable carbon sources. Carbon 232-238 putative electron-transferring-flavoprotein dehydrogenase Saccharomyces cerevisiae S288C 73-77 20701747-7 2010 The usually calculated lung cancer SMR statistic in a cohort of carbon black workers overestimated effect and precision when compared with the Bayesian results. Carbon 64-70 LY6/PLAUR domain containing 4 Homo sapiens 35-38 20512324-1 2010 Since Saccharomyces cerevisiae contains Delta9 fatty acid desaturase (OLE1) as a sole fatty acid desaturase, it produces saturated and monounsaturated fatty acids of 16- and 18-carbon compounds. Carbon 177-183 stearoyl-CoA 9-desaturase Saccharomyces cerevisiae S288C 70-74 20463027-3 2010 The final step, in which a two-carbon unit is cleaved from the fatty acid, is performed by a 3-ketoacyl-CoA thiolase (KAT). Carbon 31-37 peroxisomal 3-keto-acyl-CoA thiolase 2 Arabidopsis thaliana 93-116 20463027-3 2010 The final step, in which a two-carbon unit is cleaved from the fatty acid, is performed by a 3-ketoacyl-CoA thiolase (KAT). Carbon 31-37 peroxisomal 3-keto-acyl-CoA thiolase 2 Arabidopsis thaliana 118-121 20499053-5 2010 We were able to identify several oxidation products with oxidation in unsaturated sn-2 acyl chain of PLPE, as long- and short-chain products with main oxidation sites on C-7, C-8, C-9, and C-12 carbons. Carbon 194-201 complement C7 Homo sapiens 170-173 20512728-6 2010 Diphenyl ether seems to perform slightly better as an auxiliary carbon source than toluene in facilitating 4-BDE degradation. Carbon 64-70 homeobox D13 Homo sapiens 109-112 20507123-1 2010 Reactions of Cl(3)SnR(1)H with Na(2)E (E = Se, Te; R(1) = C(2)H(4)COO) in liquid ammonia afforded the salts of an anionic defect heterocubane, [(RSn)(3)Se(4)](-) (R = R(1) and R(1)H) or an (infinity)(1)[(R(1)Sn)(2)Te(3)(2-)] anionic polymer, respectively. Carbon 13-14 CAP-Gly domain containing linker protein 1 Homo sapiens 145-148 20802786-1 2010 A vertically aligned carbon nanofiber array coated with anatase TiO(2) (CNF/TiO(2)) is an attractive possible replacement for the sintered TiO(2) nanoparticle network in the original dye-sensitized solar cell (DSSC) design due to the potential for improved charge transport and reduced charge recombination. Carbon 21-27 NPHS1 adhesion molecule, nephrin Homo sapiens 72-75 20550396-1 2010 The nu(5) antisymmetric stretching mode of the linear carbon cluster C(7) has been revisited using a sensitive high-resolution spectrometer, including an external-cavity quantum cascade laser covering the range of interest of 1894-1901 cm(-1). Carbon 54-60 complement C7 Homo sapiens 69-73 20450210-7 2010 After comparing the energy barrier of the Pd-catalyzed decarboxylation reaction (DeltaG(decarboxylation)++) with the related C-COOH BDE, a negative correlation between the DeltaG(decarboxylation)++ and the C-COOH BDE was found. Carbon 125-127 homeobox D13 Homo sapiens 132-135 20450210-7 2010 After comparing the energy barrier of the Pd-catalyzed decarboxylation reaction (DeltaG(decarboxylation)++) with the related C-COOH BDE, a negative correlation between the DeltaG(decarboxylation)++ and the C-COOH BDE was found. Carbon 125-127 homeobox D13 Homo sapiens 213-216 20185816-8 2010 Net GNG flux was restored to basal by 4 h, despite a substantial reduction in PEPCK protein, as gluconeogenically-derived carbon was redirected from lactate efflux to glycogen deposition. Carbon 122-128 phosphoenolpyruvate carboxykinase 1 Canis lupus familiaris 78-83 21179943-7 2010 The data suggested that multiwalled carbon nanotubes may affect the transport activity of cell membrane multidrug resistance-related protein through reduction of intracellular glutathione content. Carbon 36-42 chromosome 19 open reading frame 48 Homo sapiens 104-140 20439704-9 2010 Reduced growth of wild-type plants in 28-h days and lhy/cca1 mutants in 24-h days was attributable to the inappropriate rate of starch degradation and the consequent carbon starvation at the end of night. Carbon 166-172 Homeodomain-like superfamily protein Arabidopsis thaliana 52-55 20501910-3 2010 Evaluations of the mutant phenotypes following carbon starvation induced by extended darkness identify similarities to those exhibited by mutants of the ETF/ETFQO complex. Carbon 47-53 electron-transfer flavoprotein:ubiquinone oxidoreductase Arabidopsis thaliana 157-162 20466640-5 2010 Yeast functional complementation test showed that trehalose-6-phosphate synthase mutant (tps1 big up tri, open), transformed by the ORF of SpTPS1 gene, can restore growth on the medium supplemented with glucose as a sole carbon source. Carbon 221-227 alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1 Saccharomyces cerevisiae S288C 89-93 20235247-4 2010 Using the bulkier iPrMe(2)Si substituents at three-coordinated carbon leads to slightly enhanced thermal stability of 2,4-diphospha-3-azapentadienes [(iPrMe(2)Si)(2)C=P](2)NR" (R"=tBu: 4 b; R"=1-Ada: 8). Carbon 63-69 adenosine deaminase Homo sapiens 195-198 20414304-7 2010 Because CH(4) is expected to be the dominant carbon-bearing species, disequilibrium processes such as vertical mixing and polymerization of methane into substances such as ethylene may be required to explain the hot Neptune"s small CH(4)-to-CO ratio, which is at least 10(5) times smaller than predicted. Carbon 45-51 alcohol dehydrogenase iron containing 1 Homo sapiens 212-215 19932554-4 2010 Further, the values of X(Nap) and mineralization extent of Nap (M(Nap)) increase linearly with the increase of C(O3,in.) Carbon 111-112 catenin beta like 1 Homo sapiens 25-28 19932554-4 2010 Further, the values of X(Nap) and mineralization extent of Nap (M(Nap)) increase linearly with the increase of C(O3,in.) Carbon 111-112 catenin beta like 1 Homo sapiens 59-62 19932554-4 2010 Further, the values of X(Nap) and mineralization extent of Nap (M(Nap)) increase linearly with the increase of C(O3,in.) Carbon 111-112 catenin beta like 1 Homo sapiens 59-62 20136329-0 2010 Spin filter effect of manganese phthalocyanine contacted with single-walled carbon nanotube electrodes. Carbon 76-82 spindlin 1 Homo sapiens 0-4 20136329-1 2010 We present a theoretical study of the spin transport through a manganese phthalocyanine (MnPc) molecule sandwiched between two semi-infinite armchair single-walled carbon nanotube (SWCNT) electrodes. Carbon 164-170 spindlin 1 Homo sapiens 38-42 20136329-5 2010 The spin filter effect of MnPc is very robust regardless of whether the open ends of the SWCNT electrodes are terminated by hydrogen, fluorine, or carbon dimers, demonstrating its promising applications in future molecular spintronics. Carbon 147-153 spindlin 1 Homo sapiens 4-8 19937002-1 2010 A commercially available screen-printed carbon electrode coated with an ex situ deposited bismuth film (BiSPCE) has been applied to the determination of Pb(II) and Zn(II) ions in tap water (Barcelona water distribution network) by means of stripping voltammetry (SV) and stripping chronopotentiometry (SCP). Carbon 40-46 nuclear RNA export factor 1 Homo sapiens 179-182 19914676-2 2010 While previous studies showed that the side chain acetyl group of L-AcK can be extended to bulkier acyl groups for Sir2 (including SIRT1)-catalyzed lysine N(epsilon)-deacylation reaction, our current study suggested that SIRT1-catalyzed deacetylation reaction had a very stringent requirement for the distance between the alpha-carbon and the side chain acetamido group, with that found in L-AcK being optimal. Carbon 328-334 sirtuin 1 Homo sapiens 131-136 20352740-1 2010 In this paper, the direct electron transfer of glucose oxidase (GOx) on carbon nanotube (CNT) mat electrode is demonstrated. Carbon 72-78 hydroxyacid oxidase 1 Homo sapiens 47-62 20352740-1 2010 In this paper, the direct electron transfer of glucose oxidase (GOx) on carbon nanotube (CNT) mat electrode is demonstrated. Carbon 72-78 hydroxyacid oxidase 1 Homo sapiens 64-67 19914242-3 2010 In the yeast Saccharomyces cerevisiae, Arc1p holds cytosolic methionyl-tRNA synthetase ((c)MRS) and glutamyl-tRNA synthetase ((c)ERS) together and plays an important role in fine tuning several cellular processes like aminoacylation, translation and carbon source adaptation. Carbon 250-256 Arc1p Saccharomyces cerevisiae S288C 39-44 20028087-2 2010 Glassy carbon and gold electrodes gave reversible electrochemical signals of an active hFMO3. Carbon 7-13 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 87-92 20028087-8 2010 In the case of benzydamine, a K(M) of 44 +/- 5 microM was measured upon application of a -600 mV bias to the enzyme immobilized on the glassy carbon electrode that is in good agreement with the values published for microsomal hFMO3 where NADPH is the electron donor. Carbon 142-148 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 226-231 20038148-2 2010 The catechol 2,3-dioxygenase (C23O) was purified from this bacterial strain when grown on naphthalene as the sole carbon and energy source. Carbon 114-120 catechol 2,3-dioxygenase Pseudomonas putida 4-28 20038148-2 2010 The catechol 2,3-dioxygenase (C23O) was purified from this bacterial strain when grown on naphthalene as the sole carbon and energy source. Carbon 114-120 catechol 2,3-dioxygenase Pseudomonas putida 30-34 20000707-4 2010 Anti products were selectively obtained from acyclic ketoesters without epimerization at an alpha-tertiary-carbon center, and these are valuable since previous catalysts often gave syn/anti mixtures or the stereochemistry has not yet been determined. Carbon 107-113 synemin Homo sapiens 181-184 22315566-2 2010 Firstly, alcohol dehydrogenase was immobilized on the surface of a glassy carbon electrode modified by cellulose acetate (CA) bonded to toluidine blue O (TBO). Carbon 74-80 aldo-keto reductase family 1 member A1 Homo sapiens 9-30 19769332-4 2009 Systematic replacement of each of the unfused carbon atoms in the phenyl ring of the indole moiety by a nitrogen atom provided four different azaindole derivatives that displayed a clear SAR for antiviral activity and all of which displayed marked improvements in pharmaceutical properties. Carbon 46-52 sarcosine dehydrogenase Homo sapiens 187-190 19484352-14 2009 This could reflect an inborn predisposition in complex regulation in one-carbon moieties transport in psoriatic patients and therefore, MTHFR genotype can be a part of genetic background of psoriasis. Carbon 73-79 methylenetetrahydrofolate reductase Homo sapiens 136-141 19930465-9 2009 Taken together, our present findings suggest that p53 is transcriptionally regulated by CREB/phospho-AMPKalpha complex and thereby contributing to the induction of apoptosis under carbon source depletion. Carbon 180-186 cAMP responsive element binding protein 1 Homo sapiens 88-92 19859938-1 2009 FeCo-graphitic carbon shell nanocrystals are a novel MRI contrast agent with unprecedented high per-metal-atom-basis relaxivity (r(1) = 97 mM(-1) sec(-1), r(2) = 400 mM(-1) sec(-1)) and multifunctional capabilities. Carbon 15-21 secretory blood group 1, pseudogene Homo sapiens 146-152 19859938-1 2009 FeCo-graphitic carbon shell nanocrystals are a novel MRI contrast agent with unprecedented high per-metal-atom-basis relaxivity (r(1) = 97 mM(-1) sec(-1), r(2) = 400 mM(-1) sec(-1)) and multifunctional capabilities. Carbon 15-21 secretory blood group 1, pseudogene Homo sapiens 173-179 19839597-0 2009 Biomonitoring of organophosphorus agent exposure by reactivation of cholinesterase enzyme based on carbon nanotube-enhanced flow-injection amperometric detection. Carbon 99-105 butyrylcholinesterase Rattus norvegicus 68-82 19863143-1 2009 Utilizing the lead-mediated arylation of beta-ketoesters and oxidative dearomatization/IMDA reaction as key steps, the two consecutive all-carbon quaternary centers (C-9 and C-10) were constructed in a stereoselective manner. Carbon 139-145 complement C9 Homo sapiens 166-169 19725554-6 2009 Isolated adducts originate from the addition of the thiol group of NAc-Cys-OMe over the carbon-carbon double bonds of carvone. Carbon 88-94 X-linked Kx blood group Homo sapiens 67-70 19725554-6 2009 Isolated adducts originate from the addition of the thiol group of NAc-Cys-OMe over the carbon-carbon double bonds of carvone. Carbon 95-101 X-linked Kx blood group Homo sapiens 67-70 12720457-0 2003 Tyrosine 89 accelerates Co-carbon bond homolysis in methylmalonyl-CoA mutase. Carbon 27-33 methylmalonyl-CoA mutase Homo sapiens 52-76 12720457-1 2003 The contribution of the active-site residue, Y89, to the trillion-fold acceleration of Co-carbon bond homolysis rate in the methylmalonyl-CoA mutase-catalyzed reaction has been evaluated by site-directed mutagenesis. Carbon 90-96 methylmalonyl-CoA mutase Homo sapiens 124-148 12615478-7 2003 Moreover, greater weight percentages of high surface energy carbon nanofibers in the PCU/CNF composite increased osteoblast adhesion while at the same time decreased fibroblast adhesion. Carbon 60-66 NPHS1 adhesion molecule, nephrin Homo sapiens 89-92 12688741-1 2003 [reaction: see text] An efficient and highly stereocontrolled approach to the 8,10-dimethyl anti-syn-anti-perhydrophenanthrene carbon skeleton starting with the Wieland-Miescher ketone is described. Carbon 127-133 synemin Homo sapiens 97-100 12657259-3 2003 Comparison with thyrsiferyl-23-acetate 1 showed that a similar spatial disposition for the hydroxy group around C-15 or C-16 was the structural feature shared by these metabolites. Carbon 0-1 placenta associated 8 Homo sapiens 112-116 12665348-0 2003 Hydrogenation and carbon-sulfur bond hydrogenolysis of benzothiophene promoted by Re2(CO)10 and H4Re4(CO)12. Carbon 18-24 G protein-coupled receptor 161 Homo sapiens 82-85 12646172-4 2003 UGT1A1 incorporated [33P]orthophosphate, which was inhibited by calphostin-C. Carbon 75-76 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 0-6 16256480-3 2003 The saturated C2-C12 amine intercalates of AlP with an even number of carbon atoms are packed with alkylamine bilayers tilted at an angle of 44.8 degrees in the interlayer region. Carbon 70-76 ATHS Homo sapiens 43-46 12751748-0 2003 Formation of prostaglandin E2, leukotriene B4 and 8-isoprostane in alveolar macrophages by ultrafine particles of elemental carbon. Carbon 124-130 cystatin 12, pseudogene Homo sapiens 27-45 12569427-1 2003 Opaque2 (O2) is a bZIP transcriptional regulatory factor involved in the control of seed storage proteins synthesis as well as carbon and nitrogen metabolism during maize seed development. Carbon 127-133 regulatory protein opaque-2 Zea mays 0-7 12569427-1 2003 Opaque2 (O2) is a bZIP transcriptional regulatory factor involved in the control of seed storage proteins synthesis as well as carbon and nitrogen metabolism during maize seed development. Carbon 127-133 regulatory protein opaque-2 Zea mays 9-11 19804897-10 2009 Individual BDE congeners, SigmaPBDEs and SigmaOCPs were significantly correlated with total organic carbon (TOC). Carbon 100-106 homeobox D13 Homo sapiens 11-14 10757750-10 2000 In an RPM2 wild-type background, pre4-2 and ump1-2 strains fail to grow at restrictive temperatures on nonfermentable carbon sources. Carbon 118-124 proteasome core particle subunit beta 7 Saccharomyces cerevisiae S288C 33-37 10757750-10 2000 In an RPM2 wild-type background, pre4-2 and ump1-2 strains fail to grow at restrictive temperatures on nonfermentable carbon sources. Carbon 118-124 Ump1p Saccharomyces cerevisiae S288C 44-48 19780152-6 2009 From the difference in glucuronide positions 5 and 3 enrichments, the fraction of direct pathway carbons that experienced transaldolase exchange was estimated at 21 +/- 4%. Carbon 97-104 transaldolase 1 Homo sapiens 122-135 10758479-0 2000 Dof1 and Dof2 transcription factors are associated with expression of multiple genes involved in carbon metabolism in maize. Carbon 97-103 Dof zinc finger protein MNB1A Zea mays 9-13 10649999-1 2000 Light generates reducing equivalents in chloroplasts that are used not only for carbon reduction, but also for the regulation of the activity of chloroplast enzymes by reduction of regulatory disulfides via the ferredoxin:thioredoxin reductase (FTR) system. Carbon 80-86 thioredoxin Homo sapiens 222-233 19683424-1 2009 A novel biosensor for glucose was prepared by immobilizing glucose oxidase (GOx) on nitrogen-doped carbon nanotubes (CNx-MWNTs) modified electrode. Carbon 99-105 hydroxyacid oxidase 1 Homo sapiens 59-74 19683424-1 2009 A novel biosensor for glucose was prepared by immobilizing glucose oxidase (GOx) on nitrogen-doped carbon nanotubes (CNx-MWNTs) modified electrode. Carbon 99-105 hydroxyacid oxidase 1 Homo sapiens 76-79 10587490-1 2000 We report the detection of a strong submillimeter-wavelength HCN laser line at a frequency near 805 GHz toward the carbon star IRC +10216. Carbon 115-121 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 61-64 19772319-2 2009 Spin trapping with 5,5"-dimethylpyrroline 1-N-oxide (DMPO) gave a composite spectrum of a carbon-centered radical and the well-known DMPO-OH adduct. Carbon 90-96 spindlin 1 Homo sapiens 0-4 19772319-4 2009 Furthermore, using the closely related spin trap 5-diethoxyphosphoryl-5-methylpyrroline N-oxide (DEPMPO), which is less prone to oxidation than DMPO, gave only a carbon-centered radical spectrum without any involvement of a (*)OH radical. Carbon 162-168 spindlin 1 Homo sapiens 39-43 19772319-5 2009 Reduction of a more soluble analogue of TPZ, in redox equilibrium with its 1-oxide derivative, led to spin trapping of both a carbon-centered radical and a nitrogen-centered radical by N-tert-butyl-alpha-phenylnitrone (PBN). Carbon 126-132 spindlin 1 Homo sapiens 102-106 11029785-7 2000 That of IHC for antibodies 1D-5, C-314, G-20, C-311 and HC-20 was 50.5%, 47.4%, 46.4%, 44.3% and 57.7%, respectively. Carbon 10-11 chromosome 3 open reading frame 18 Homo sapiens 40-44 19731956-6 2009 The bis-sulfamates incorporating 8 or 10 carbon atoms showed higher affinity for the tumor-associated hCA IX compared to hCA II, whereas the opposite was true for the monosulfamates. Carbon 41-47 carbonic anhydrase 2 Homo sapiens 121-127 19775184-1 2009 Enantioenriched allenylsilanes are used as carbon nucleophiles in three-component reactions with in situ generated N-sulfonylimines to selectively form syn-homopropargylic sulfonamides. Carbon 43-49 synemin Homo sapiens 152-155 19774086-7 2009 CONCLUSIONS/SIGNIFICANCE: Transcription analysis and gene silencing of LKR/SDH indicated that tick LKR/SDH enzyme plays not only important roles in egg production, reproduction and development of the tick, but also in carbon, nitrogen and water balance, crucial physiological processes for the survival of ticks. Carbon 218-224 aminoadipate-semialdehyde synthase Homo sapiens 71-78 19774086-7 2009 CONCLUSIONS/SIGNIFICANCE: Transcription analysis and gene silencing of LKR/SDH indicated that tick LKR/SDH enzyme plays not only important roles in egg production, reproduction and development of the tick, but also in carbon, nitrogen and water balance, crucial physiological processes for the survival of ticks. Carbon 218-224 aminoadipate-semialdehyde synthase Homo sapiens 99-106 14580939-3 2003 External application of group IIA sPLA2 (purified crotoxin subunit B or purified human synovial sPLA2) caused an immediate increase in exocytosis and neurotransmitter release in pheochromocytoma-12 (PC12) cells, detected by carbon fiber electrodes placed near the cells, or by changes in membrane capacitance of the cells. Carbon 224-230 phospholipase A2 group IIA Homo sapiens 34-39 19362414-3 2009 The results obtained showed that the adsorb ability of (RhB) to the BPH is higher than that of the BPK carbon by approximately 10 folds (198.6 and 21.5 mg g(-1), respectively). Carbon 103-109 Bruton tyrosine kinase Homo sapiens 99-102 12881894-10 2000 However, this interaction was in the opposite direction in young rats versus old rats and old TSK mice: Carbon and ozone interacted such that ROS activity was depressed in young rats, whereas it was enhanced in old rats and old TSK mice, indicating age-dependent functional differences in elicited pulmonary inflammatory cells. Carbon 104-110 tsukushi, small leucine rich proteoglycan Mus musculus 94-97 19615522-0 2009 Carbon felt-based biocatalytic enzymatic flow-through detectors: chemical modification of tyrosinase onto amino-functionalized carbon felt using various coupling reagents. Carbon 0-6 tyrosinase Homo sapiens 90-100 19615522-0 2009 Carbon felt-based biocatalytic enzymatic flow-through detectors: chemical modification of tyrosinase onto amino-functionalized carbon felt using various coupling reagents. Carbon 127-133 tyrosinase Homo sapiens 90-100 19615522-1 2009 Tyrosinase (TYR) was covalently immobilized onto amino-functionalized carbon felt (CF) surface via eight different coupling reagents. Carbon 70-76 tyrosinase Homo sapiens 0-10 19615522-1 2009 Tyrosinase (TYR) was covalently immobilized onto amino-functionalized carbon felt (CF) surface via eight different coupling reagents. Carbon 70-76 tyrosinase Homo sapiens 12-15 12392962-0 2002 Analysis of thiols with tyrosinase-modified carbon paste electrodes based on blocking of substrate recycling. Carbon 44-50 tyrosinase Homo sapiens 24-34 12392962-1 2002 The enzyme, tyrosinase, was immobilized inside carbon paste electrodes (CPE) for the analysis of thiol-containing compounds such as the reduced form of glutathione (GSH) and L-cysteine. Carbon 47-53 tyrosinase Homo sapiens 12-22 12491008-4 2002 The maf1-delta mutation did not affect the rate of protein biosynthesis and growth at standard conditions, but resulted in temperature-sensitive growth on non-fermentable carbon sources. Carbon 171-177 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 4-8 19739873-2 2009 The three-dimensional ZF-TEDOR pulse sequence is employed in combination with sparse labeling of (13)C sites in the beta1 domain of the immunoglobulin binding protein G (GB1), as obtained by bacterial expression with 1,3-(13)C or 2-(13)C-glycerol as the (13)C source. Carbon 100-102 gamma-aminobutyric acid type B receptor subunit 1 Homo sapiens 170-173 12881894-10 2000 However, this interaction was in the opposite direction in young rats versus old rats and old TSK mice: Carbon and ozone interacted such that ROS activity was depressed in young rats, whereas it was enhanced in old rats and old TSK mice, indicating age-dependent functional differences in elicited pulmonary inflammatory cells. Carbon 104-110 tsukushi, small leucine rich proteoglycan Mus musculus 228-231 19724679-12 2009 In conclusion, carbon ion irradiation upregulates ICAM-1 and alpha(v)beta(3)-integrin expression in tumor neovasculature. Carbon 15-21 intercellular adhesion molecule 1 Rattus norvegicus 50-56 16232772-1 2000 In the course of studying carboxypeptidase Y (CPY) production, we found that the expression level of the gene, which is under the control of the GAL10 promoter, increased in a Saccharomyces cerevisiae gal80 mutant grown in a medium containing ethanol as the sole carbon source. Carbon 263-269 bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase Saccharomyces cerevisiae S288C 145-150 12505520-2 2002 NK cells expressing Ly49G2 were selectively expanded by several viruses and poly I:C. CD8(+) T cells expressing Ly49G2 were selectively expanded by poly I:C and participated in the antigen-specific response to lymphocytic choriomeningitis virus. Carbon 83-84 CD8a molecule Homo sapiens 86-89 16232772-1 2000 In the course of studying carboxypeptidase Y (CPY) production, we found that the expression level of the gene, which is under the control of the GAL10 promoter, increased in a Saccharomyces cerevisiae gal80 mutant grown in a medium containing ethanol as the sole carbon source. Carbon 263-269 transcription regulator GAL80 Saccharomyces cerevisiae S288C 201-206 12381177-3 2002 Employing this reaction allows simplification of the target to three subunits corresponding to C-1 to C-6, C-7 to C-15, and C-16 to C-25. Carbon 95-96 placenta associated 8 Homo sapiens 114-118 10717647-9 2000 Protonated oximes of 20-oxosteroids unsubstituted at C-21, C-17 or C-16 produced a characteristic ion at m/z 86 containing the side chain, C-16 and C-17. Carbon 53-54 cytokine like 1 Homo sapiens 148-152 12383018-2 2002 SAR of spiro[[2]benzopyran-1,4"-piperidines] and spiro[[2]benzofuran-1,4"-piperidines] with carbon substituents in position 3. Carbon 92-98 sarcosine dehydrogenase Homo sapiens 0-3 12387322-2 2002 A hollow cylinder comprised of DuPont"s Vespel SP-22, a polymer loaded with conductive carbon particles, is used to enhance the performance of a hybrid reflectron compared to a conventional dual stage gridless reflectron composed of discrete metal ring electrodes. Carbon 87-93 peroxiredoxin 3 Homo sapiens 47-52 19435308-0 2009 Computational study of a nanobiosensor: a single-walled carbon nanotube functionalized with the coxsackie-adenovirus receptor. Carbon 56-62 CXADR Ig-like cell adhesion molecule Homo sapiens 96-125 10717647-9 2000 Protonated oximes of 20-oxosteroids unsubstituted at C-21, C-17 or C-16 produced a characteristic ion at m/z 86 containing the side chain, C-16 and C-17. Carbon 59-60 cytokine like 1 Homo sapiens 148-152 10611466-4 1999 The major quantitative route of carbon flux in the liver during S 4048-induced inhibition of the glucose-6-phosphatase activity seemed to be glycogenesis. Carbon 32-38 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 97-118 19652403-5 2009 Analgesic activity data of these C(18)- and C(19)-diterpenoid alkaloids indicate that a tertiary amine in ring A, an acetoxyl or an ethoxyl group at C-8, an aromatic ester at C-14, and the saturation state of the ring D are important structural features necessary to the analgesic activity of the C(19)-diterpenoid alkaloids. Carbon 33-34 cell division cycle associated 3 Mus musculus 149-152 19392706-3 2009 In mature and desiccated aap1 seeds the total N and carbon content was reduced while the total free amino acid levels were strongly increased. Carbon 52-58 amino acid permease 1 Arabidopsis thaliana 25-29 12227809-1 2002 Synthetic methodology that allows for incorporation of isotopic carbon at the C-3 and C-4 positions of bile salts is reported. Carbon 64-70 complement C3 Homo sapiens 78-81 12370778-1 2002 Methylenetetrahydrofolate reductase (MTHFR) reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, the major carbon donor in the remethylation of homocysteine to methionine. Carbon 122-128 methylenetetrahydrofolate reductase Homo sapiens 0-35 12370778-1 2002 Methylenetetrahydrofolate reductase (MTHFR) reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, the major carbon donor in the remethylation of homocysteine to methionine. Carbon 122-128 methylenetetrahydrofolate reductase Homo sapiens 37-42 10628845-3 1999 We therefore examined the role of the heme-dependent transcriptional activator Hap1p and the carbon source-dependent Hap2/3/4/5 complex. Carbon 93-99 Hap5p Saccharomyces cerevisiae S288C 117-127 19572757-5 2009 The first spin inversion, from the sextet state to the quartet state, makes the activation of the C-H bond energetically spontaneous. Carbon 98-99 spindlin 1 Homo sapiens 10-14 12186556-8 2002 Similar experiments with Cinn-GEE that had been labeled with (13)C at the benzylic position revealed a change in the hybridization state (from sp(2) to sp(3)) for the benzylic carbon as a result of binding to PTP1B. Carbon 176-182 CINN Homo sapiens 25-29 10628845-4 1999 We found that the Hap2/3/4/5 complex and Hap1p have additive effects on the activation of DLD1 transcription: the Hap2/3/4/5 complex is necessary for DLD1 derepression following a shift from fermentable to non-fermentable carbon sources, while the Hap1p effect was independent of the carbon sources tested. Carbon 222-228 Hap5p Saccharomyces cerevisiae S288C 18-28 12186556-8 2002 Similar experiments with Cinn-GEE that had been labeled with (13)C at the benzylic position revealed a change in the hybridization state (from sp(2) to sp(3)) for the benzylic carbon as a result of binding to PTP1B. Carbon 176-182 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 209-214 10628845-4 1999 We found that the Hap2/3/4/5 complex and Hap1p have additive effects on the activation of DLD1 transcription: the Hap2/3/4/5 complex is necessary for DLD1 derepression following a shift from fermentable to non-fermentable carbon sources, while the Hap1p effect was independent of the carbon sources tested. Carbon 222-228 Hap1p Saccharomyces cerevisiae S288C 41-46 19621084-7 2009 Crystal structures of the TTR:inhibitor complexes, in agreement with molecular docking studies, revealed that the aromatic moiety, linked to the sp(2)-hybridized oxime carbon, specifically directed the ligand in either a forward or reverse binding mode. Carbon 168-174 transthyretin Homo sapiens 26-29 10628845-4 1999 We found that the Hap2/3/4/5 complex and Hap1p have additive effects on the activation of DLD1 transcription: the Hap2/3/4/5 complex is necessary for DLD1 derepression following a shift from fermentable to non-fermentable carbon sources, while the Hap1p effect was independent of the carbon sources tested. Carbon 222-228 Hap5p Saccharomyces cerevisiae S288C 114-124 10628845-4 1999 We found that the Hap2/3/4/5 complex and Hap1p have additive effects on the activation of DLD1 transcription: the Hap2/3/4/5 complex is necessary for DLD1 derepression following a shift from fermentable to non-fermentable carbon sources, while the Hap1p effect was independent of the carbon sources tested. Carbon 222-228 Hap1p Saccharomyces cerevisiae S288C 248-253 10628845-4 1999 We found that the Hap2/3/4/5 complex and Hap1p have additive effects on the activation of DLD1 transcription: the Hap2/3/4/5 complex is necessary for DLD1 derepression following a shift from fermentable to non-fermentable carbon sources, while the Hap1p effect was independent of the carbon sources tested. Carbon 284-290 Hap5p Saccharomyces cerevisiae S288C 18-28 12214665-2 2002 The initial step in the overall reaction is the two-electron ring alpha-carbon oxidation to give the 1-methyl-4-phenyl-2,3-dihydropyridinium species, a reaction that is catalyzed by monoamine oxidase B. Carbon 72-78 monoamine oxidase B Homo sapiens 182-201 10628845-4 1999 We found that the Hap2/3/4/5 complex and Hap1p have additive effects on the activation of DLD1 transcription: the Hap2/3/4/5 complex is necessary for DLD1 derepression following a shift from fermentable to non-fermentable carbon sources, while the Hap1p effect was independent of the carbon sources tested. Carbon 284-290 Hap1p Saccharomyces cerevisiae S288C 41-46 12533227-0 2002 Early stages of carbon segregation and precipitation in a sigma = 5 (310)[001] molybdenum tilt boundary. Carbon 16-22 adaptor related protein complex 5 subunit sigma 1 Homo sapiens 58-67 12533227-1 2002 A [Sigma] = 5 (310)[001] tilt grain boundary in molybdenum has been annealed at high temperature in the presence of carbon and observed in high-resolution electron microscopy. Carbon 116-122 adaptor related protein complex 5 subunit sigma 1 Homo sapiens 3-13 19504529-1 2009 Double aromaticity of neutral, planar rings of carbon atoms is demonstrated through visualisation of the induced ring currents, mapped at the ipsocentric B3LYP/6-31G(d)//B3LYP/6-31G(d) level for species C(6) to C(30), with onset of delocalised current in the in-plane pi system at C(10)/C(11). Carbon 47-53 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 156-159 10628845-4 1999 We found that the Hap2/3/4/5 complex and Hap1p have additive effects on the activation of DLD1 transcription: the Hap2/3/4/5 complex is necessary for DLD1 derepression following a shift from fermentable to non-fermentable carbon sources, while the Hap1p effect was independent of the carbon sources tested. Carbon 284-290 Hap5p Saccharomyces cerevisiae S288C 114-124 10628845-4 1999 We found that the Hap2/3/4/5 complex and Hap1p have additive effects on the activation of DLD1 transcription: the Hap2/3/4/5 complex is necessary for DLD1 derepression following a shift from fermentable to non-fermentable carbon sources, while the Hap1p effect was independent of the carbon sources tested. Carbon 284-290 Hap1p Saccharomyces cerevisiae S288C 248-253 10628872-0 1999 Cat8p, the activator of gluconeogenic genes in Saccharomyces cerevisiae, regulates carbon source-dependent expression of NADP-dependent cytosolic isocitrate dehydrogenase (Idp2p) and lactate permease (Jen1p). Carbon 83-89 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 0-5 12203539-0 2002 Synthesis and structure of (MeN)Ph2S=C=SPh2(NMe). Carbon 37-38 ankyrin 1 Homo sapiens 39-43 10628872-0 1999 Cat8p, the activator of gluconeogenic genes in Saccharomyces cerevisiae, regulates carbon source-dependent expression of NADP-dependent cytosolic isocitrate dehydrogenase (Idp2p) and lactate permease (Jen1p). Carbon 83-89 Jen1p Saccharomyces cerevisiae S288C 201-206 10628872-1 1999 The yeast transcriptional activator Cat8p has been identified as a factor that is essential for the derepression of genes involved in gluconeogenesis (like FBP1, PCK1, ACR1, ICL1 and MLS1) when only nonfermentable carbon sources are provided. Carbon 214-220 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 36-41 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 115-116 aldo-keto reductase family 1 member C4 Homo sapiens 201-206 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 122-123 placenta associated 8 Homo sapiens 115-120 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 122-123 placenta associated 8 Homo sapiens 115-120 19391105-5 2009 The amounts of medium-chain acyl-CoAs (C(6), C(8) and C(10)) were less than long-chain acyl-CoAs (C(16:0), C(18:0), C(18:1) and C(20:4)) in both liver and brain. Carbon 33-34 gene rich cluster, C10 gene Mus musculus 54-59 10628872-1 1999 The yeast transcriptional activator Cat8p has been identified as a factor that is essential for the derepression of genes involved in gluconeogenesis (like FBP1, PCK1, ACR1, ICL1 and MLS1) when only nonfermentable carbon sources are provided. Carbon 214-220 phosphoenolpyruvate carboxykinase PCK1 Saccharomyces cerevisiae S288C 162-166 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 122-123 placenta associated 8 Homo sapiens 115-120 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 122-123 placenta associated 8 Homo sapiens 115-120 19534558-4 2009 It was found that the field enhancement factor was overestimated by about a factor 2 in the classical calculation (for the capped carbon nanotube). Carbon 130-136 transcription termination factor 2 Homo sapiens 76-84 10628872-1 1999 The yeast transcriptional activator Cat8p has been identified as a factor that is essential for the derepression of genes involved in gluconeogenesis (like FBP1, PCK1, ACR1, ICL1 and MLS1) when only nonfermentable carbon sources are provided. Carbon 214-220 Arr1p Saccharomyces cerevisiae S288C 168-172 10625471-3 1999 One of the active site residues is lysine-32, which is postulated to play two roles: it assists in substrate binding through an interaction with a carboxylate oxygen at C-1 of phenylpyruvate, and it may be partially responsible for lowering the pK(a) of the catalytic base, Pro-1. Carbon 169-170 lamin A/C Homo sapiens 274-279 21582899-2 2009 The conformation of the N-H bond in the structure is syn to the C=O bond in one of the mol-ecules and anti in the other. Carbon 64-65 synemin Homo sapiens 53-56 12049754-1 2002 A novel tyrosinase biosensor has been developed for a subpicomolar detection of phenols, which is based on the immobilization of tyrosinase in a positively charged chitosan film on a glassy carbon electrode. Carbon 190-196 tyrosinase Homo sapiens 8-18 12049754-1 2002 A novel tyrosinase biosensor has been developed for a subpicomolar detection of phenols, which is based on the immobilization of tyrosinase in a positively charged chitosan film on a glassy carbon electrode. Carbon 190-196 tyrosinase Homo sapiens 129-139 12135569-1 2002 The bacterial PII protein was discovered over 30 years ago and is known to be a key player in orchestrating the coordination of nitrogen metabolism with changes in carbon flux. Carbon 164-170 nitrogen regulatory P-II-like protein Arabidopsis thaliana 14-17 10581109-8 1999 Long-term incubation with IFN-gamma markedly impaired both the accumulated attachment (to 3.8 particles/AM) and the ingested fraction (to 0.24) in unloaded AM and the carbon load further decreased the accumulated attachment to 2.8 particles/AM, and the ingested fraction to 0.21. Carbon 167-173 interferon gamma Rattus norvegicus 26-35 12135569-2 2002 Bacterial PII is regulated by covalent modification and binding to effector molecules in response to the nitrogen/carbon status of the cell and appropriately coordinates the activity of glutamine synthetase and the transcription of a nitrogen sensitive regulon. Carbon 114-120 nitrogen regulatory P-II-like protein Arabidopsis thaliana 10-13 12011491-9 2002 In rats exposed to P=S and C=S but not MP=S, ChE inhibition was lower in PCB-treated rats than in oil-treated rats. Carbon 27-28 butyrylcholinesterase Rattus norvegicus 45-48 19513449-8 2009 Significant correlations were found between BDE-209 and organic carbon (OC) or elemental carbon (EC) in the two cities, suggesting that combustion may be an important pathway introducing BDE-209 to the atmosphere. Carbon 64-70 homeobox D13 Homo sapiens 44-47 19513449-8 2009 Significant correlations were found between BDE-209 and organic carbon (OC) or elemental carbon (EC) in the two cities, suggesting that combustion may be an important pathway introducing BDE-209 to the atmosphere. Carbon 89-95 homeobox D13 Homo sapiens 44-47 19513449-8 2009 Significant correlations were found between BDE-209 and organic carbon (OC) or elemental carbon (EC) in the two cities, suggesting that combustion may be an important pathway introducing BDE-209 to the atmosphere. Carbon 97-99 homeobox D13 Homo sapiens 44-47 19385592-3 2009 The spin density distributions in the triplet state were found to be similar for bacteriochlorophyll a and bacteriochlorophyll b except for the presence of spin density on carbon 8(1) in bacteriochlorophyll b. Judging from a comparison with ENDOR experiments for the radical cation and anion, the triplet state in bacteriochlorophylls cannot be explained as being a simple HOMO-->LUMO excitation of Gouterman orbitals. Carbon 172-178 spindlin 1 Homo sapiens 156-160 12011491-9 2002 In rats exposed to P=S and C=S but not MP=S, ChE inhibition was lower in PCB-treated rats than in oil-treated rats. Carbon 27-28 pyruvate carboxylase Rattus norvegicus 73-76 10564066-6 1999 Compounds with 9-11 carbons at C-3 and 6-10 carbons at C-2 provided good separation (up to 2.7-fold) between activity and cytotoxicity. Carbon 20-27 complement C2 Homo sapiens 55-58 12086601-4 2002 Hda1 also deacetylates subtelomeric domains containing normally repressed genes that are used instead for gluconeogenesis, growth on carbon sources other than glucose, and adverse growth conditions. Carbon 133-139 histone deacetylase HDA1 Saccharomyces cerevisiae S288C 0-4 19144510-3 2009 5,10-Methylenetetrahydrofolate reductase (MTHFR), a key enzyme of one-carbon metabolism, catalyses the irreversible conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. Carbon 70-76 methylenetetrahydrofolate reductase Homo sapiens 42-47 10564066-6 1999 Compounds with 9-11 carbons at C-3 and 6-10 carbons at C-2 provided good separation (up to 2.7-fold) between activity and cytotoxicity. Carbon 44-51 complement C2 Homo sapiens 55-58 19852088-3 2009 A DNA repair protein in Escherichia coli, AlkB, corrects some of the unwanted methylations of DNA bases by a unique oxidative demethylation in which the methyl carbon is liberated as formaldehyde. Carbon 160-166 alkB homolog 1, histone H2A dioxygenase Homo sapiens 42-46 10517471-14 1999 Treating the system with IFN-gamma in advance, inhibited poly-I:C-induced inflammation, shown by marked decreases in rolling, adhering, and transmigrating leukocytes, and a notable increase in perfused capillaries. Carbon 64-65 interferon gamma Rattus norvegicus 25-34 19275141-0 2009 Spin state splitting in carbon gasification models. Carbon 24-30 spindlin 1 Homo sapiens 0-4 12074825-5 2002 DESIGN AND METHODS: The activity of DPD was measured using 5-[2- (14)C]Fluorouracil (5-[2-(14)C]FUra) followed by separation of substrate and product 5-[2-(14)C]FUraH(2) with a 15 x 4.6 mm I.D., 5 microm particle size (d(p)) porous graphitic carbon (PGC) column (Hypercarb(R)) and HPLC with online detection of the radioactivity. Carbon 242-248 dihydropyrimidine dehydrogenase Homo sapiens 36-39 11960494-7 2002 A docking study in combination with site-directed mutation analysis revealed that two carbon elongated side chain analogue 3 could be fitted in the ligand binding pocket of the VDR by adopting a stable conformation. Carbon 86-92 vitamin D receptor Homo sapiens 177-180 19396235-3 2009 Both chitinase and beta-1,3-glucanase enzymes were produced when C. rosea was grown on a synthetic medium containing chitin or laminarin as a sole carbon source, respectively. Carbon 147-153 acidic endochitinase Cucumis sativus 5-14 10525741-0 1999 Ethene as an auxiliary substrate for the cooxidation of cis-1, 2-dichloroethene and vinyl chloride Cultures able to dechlorinate cis-1,2-dichloroethene (cDCE) were selected with ethene (3-20%, v/v) as the sole source of carbon and energy. Carbon 220-226 suppressor of cytokine signaling 1 Homo sapiens 56-61 12054566-4 2002 SPT3 and SNF2 activated GDH1 expression on either carbon source whereas GCN5 played no role in any condition tested. Carbon 50-56 transcriptional regulator SPT3 Saccharomyces cerevisiae S288C 0-4 12054566-4 2002 SPT3 and SNF2 activated GDH1 expression on either carbon source whereas GCN5 played no role in any condition tested. Carbon 50-56 SWI/SNF catalytic subunit SNF2 Saccharomyces cerevisiae S288C 9-13 19636204-6 2009 TAb were more frequent in c-BTN than c-PTC in females with MNG (40.1% vs 32.5%, p=0.02), and in c-PTC than in c-BTN in males with S/I (31.2% vs 20.4%, p=0.02) and, although not significantly, in females younger than 30 yr (35.1% vs 30.7%). Carbon 26-27 butyrophilin subfamily 1 member A1 Homo sapiens 28-31 10525741-0 1999 Ethene as an auxiliary substrate for the cooxidation of cis-1, 2-dichloroethene and vinyl chloride Cultures able to dechlorinate cis-1,2-dichloroethene (cDCE) were selected with ethene (3-20%, v/v) as the sole source of carbon and energy. Carbon 220-226 suppressor of cytokine signaling 1 Homo sapiens 129-134 10523022-12 1999 Thus, CRH is coupled to the phospholipase C-inositol phosphate second messenger system and preferentially induces the expression of P450c17 and DHEAS, suggesting a unique role of CRH regulating human fetal adrenal function via PKC. Carbon 42-44 corticotropin releasing hormone Homo sapiens 6-9 19243140-0 2009 Conjugation of antisense oligonucleotides to PEGylated carbon nanotubes enables efficient knockdown of PTPN22 in T lymphocytes. Carbon 55-61 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 103-109 11929297-5 2002 The formation of hydroxyl and carbon-centered radicals was indicated by electron paramagnetic resonance spectra using alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone or 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide as spin traps. Carbon 30-36 spindlin 1 Homo sapiens 222-226 10537204-5 1999 It is now shown that the gene is expressed in the parental organism and that GST activity is induced more than 20-fold by growth of the strain on BP relative to succinate when these compounds serve as sole carbon source. Carbon 206-212 glutathione S-transferase Paraburkholderia xenovorans LB400 77-80 11866583-5 2002 In reactions involving ketone donors where diastereoisomeric products could be formed, two adjacent stereogenic centers were created simultaneously upon carbon-carbon bond formation with complete syn-stereocontrol. Carbon 153-159 synemin Homo sapiens 196-199 11866583-5 2002 In reactions involving ketone donors where diastereoisomeric products could be formed, two adjacent stereogenic centers were created simultaneously upon carbon-carbon bond formation with complete syn-stereocontrol. Carbon 160-166 synemin Homo sapiens 196-199 10540293-3 1999 Expression of CAT8 as well as transcriptional activation by Cat8p is regulated by the carbon source, requiring a functional Cat1p (= Snf1p) protein kinase. Carbon 86-92 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 14-18 10540293-3 1999 Expression of CAT8 as well as transcriptional activation by Cat8p is regulated by the carbon source, requiring a functional Cat1p (= Snf1p) protein kinase. Carbon 86-92 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 60-65 11904149-1 2002 The yeast high-affinity glucose transporters Hxt6p and Hxt7p are rapidly degraded during nitrogen starvation in the presence of high concentrations of fermentable carbon sources. Carbon 163-169 hexose transporter HXT6 Saccharomyces cerevisiae S288C 45-50 10509015-3 1999 We have isolated and characterized three HOM3 mutants that show growth inhibition by threonine due to a severe, threonine-induced reduction of the carbon flow into the aspartate pathway, leading to methionine limitation. Carbon 147-153 aspartate kinase Saccharomyces cerevisiae S288C 41-45 11756263-4 2002 Feedbacks involved in scaling from leaf to crop constrain the increase in net carbon gain and reduce the anti-transpiration effect of CO(2) enrichment. Carbon 78-84 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 43-47 12188577-6 2002 An anaerobic bacterium that is responsible for the formation of MT and DMS through the anaerobic methylation of H2S and MT was isolated from a freshwater pond after enrichment with syringate as a methyl group donating compound and sole carbon source. Carbon 236-242 histamine N-methyltransferase Homo sapiens 112-122 11596746-6 2001 For LAS, the organic carbon-based partition coefficient values were between 2.4 x 10(3) and 6.6 x 10(5)L/kg for the C10 and C13 homologues, respectively; these values are similar to those obtained from laboratory tests for the sorption of LAS onto marine sediments. Carbon 21-27 homeobox C13 Homo sapiens 124-127 10508789-1 1999 BACKGROUND: Fumarylacetoacetate hydrolase (FAH) catalyzes the final step of tyrosine and phenylalanine catabolism, the hydrolytic cleavage of a carbon-carbon bond in fumarylacetoacetate, to yield fumarate and acetoacetate. Carbon 144-150 fumarylacetoacetate hydrolase Homo sapiens 12-41 11556805-1 2001 NEUT2 mice are deficient in cytosolic 10-formyltetrahydrofolate dehydrogenase (FDH; EC 1.5.1.6) which catalyzes the oxidation of excess folate-linked one-carbon units in the form of 10-formyltetrahydrofolate to CO(2) and tetrahydrofolate (Champion et al., Proc. Carbon 154-160 aldehyde dehydrogenase 1 family, member L1 Mus musculus 0-5 11556805-1 2001 NEUT2 mice are deficient in cytosolic 10-formyltetrahydrofolate dehydrogenase (FDH; EC 1.5.1.6) which catalyzes the oxidation of excess folate-linked one-carbon units in the form of 10-formyltetrahydrofolate to CO(2) and tetrahydrofolate (Champion et al., Proc. Carbon 154-160 aldehyde dehydrogenase 1 family, member L1 Mus musculus 28-77 11556805-1 2001 NEUT2 mice are deficient in cytosolic 10-formyltetrahydrofolate dehydrogenase (FDH; EC 1.5.1.6) which catalyzes the oxidation of excess folate-linked one-carbon units in the form of 10-formyltetrahydrofolate to CO(2) and tetrahydrofolate (Champion et al., Proc. Carbon 154-160 aldehyde dehydrogenase 1 family, member L1 Mus musculus 79-82 10508789-1 1999 BACKGROUND: Fumarylacetoacetate hydrolase (FAH) catalyzes the final step of tyrosine and phenylalanine catabolism, the hydrolytic cleavage of a carbon-carbon bond in fumarylacetoacetate, to yield fumarate and acetoacetate. Carbon 144-150 fumarylacetoacetate hydrolase Homo sapiens 43-46 10508789-1 1999 BACKGROUND: Fumarylacetoacetate hydrolase (FAH) catalyzes the final step of tyrosine and phenylalanine catabolism, the hydrolytic cleavage of a carbon-carbon bond in fumarylacetoacetate, to yield fumarate and acetoacetate. Carbon 151-157 fumarylacetoacetate hydrolase Homo sapiens 12-41 10508789-1 1999 BACKGROUND: Fumarylacetoacetate hydrolase (FAH) catalyzes the final step of tyrosine and phenylalanine catabolism, the hydrolytic cleavage of a carbon-carbon bond in fumarylacetoacetate, to yield fumarate and acetoacetate. Carbon 151-157 fumarylacetoacetate hydrolase Homo sapiens 43-46 11409176-6 2001 Thus, the HSP26 and the HSP30 promoter can be used for late, phase-specific expression of the desired genes with glucose or maltose as carbon source, and HSP12 with glucose only. Carbon 135-141 chaperone protein HSP26 Saccharomyces cerevisiae S288C 10-15 10508789-11 1999 CONCLUSIONS: FAH represents the first structure of a hydrolase that acts specifically on carbon-carbon bonds. Carbon 89-95 fumarylacetoacetate hydrolase Homo sapiens 13-16 10508789-11 1999 CONCLUSIONS: FAH represents the first structure of a hydrolase that acts specifically on carbon-carbon bonds. Carbon 96-102 fumarylacetoacetate hydrolase Homo sapiens 13-16 10423385-12 1999 The new 3D S(3) TPPI TROSY HCCH method is demonstrated on a (13)C,(15)N-labeled protein sample, RAP 18-112 (N-terminal domain of alpha(2)-macroglobulin receptor associated protein), at 750 MHz and average sensitivity enhancements of 10% are obtained for the cross peaks in comparison to methods based on conventional decoupling on one of the carbons or on TROSY on both carbons. Carbon 342-349 LDL receptor related protein associated protein 1 Homo sapiens 96-99 10450986-1 1999 A tether length study of C32-O-phenalkyl ether derivatives of ascomycin was conducted wherein it was determined that a 2-carbon tether provides optimum in vitro immunosuppressive activity. Carbon 121-127 chemokine like factor Homo sapiens 25-28 11337077-1 2001 We have integrated two cDNAs expressing Sorghum photosynthetic phosphoenolpyruvate carboxylase (C(4)-PEPC) and NADP-malate dehydrogenase (cpMDH), two key enzymes involved in the primary carbon fixation pathway of NADP-malic enzyme-type C(4) plants, separately or together into a C(3) plant (potato). Carbon 186-192 phosphoenolpyruvate carboxylase Solanum tuberosum 101-105 11305908-3 2001 Cytoplasmic SHMT (cSHMT) has been postulated to channel one-carbon substituted folates to various folate-dependent enzymes, and alternative splicing of the cSHMT transcript may be a mechanism that enables specific protein-protein interactions. Carbon 60-66 serine hydroxymethyltransferase 1 (soluble) Mus musculus 12-16 10383958-3 1999 The specific activities of three enzymes, an alpha-glucosidase (malA), a beta-glycosidase (lacS), and an alpha-amylase, were reduced 4-, 20-, and 10-fold, respectively, in response to the addition of supplementary carbon sources to a minimal sucrose medium. Carbon 214-220 glycoside hydrolase family 57 protein Saccharolobus solfataricus 105-118 18968259-0 2001 A chemically modified carbon paste electrode with d-lactate dehydrogenase and alanine aminotranferase enzyme sequences for d-lactic acid analysis. Carbon 22-28 lactate dehydrogenase D Homo sapiens 50-73 10403382-1 1999 The proposed rate-limiting step of the reaction catalyzed by glyoxalase I is the proton abstraction from the C1 carbon atom of the substrate by a glutamate residue, resulting in a high-energy enolate intermediate. Carbon 112-118 glyoxalase I Homo sapiens 61-73 11346956-7 2001 The effect of SPS on growth was the result of a shift in partitioning of carbon among starch, sucrose, and ionic compounds (primarily amino acids), rather than of an increase in net photosynthesis. Carbon 73-79 sucrose-phosphate synthase Solanum lycopersicum 14-17 10329181-1 1999 The PutR protein of Agrobacterium tumefaciens positively regulates expression of the putA gene in response to exogenous proline, resulting in the utilization of proline as a source of carbon and nitrogen. Carbon 184-190 putA Agrobacterium tumefaciens 85-89 11277529-0 2001 Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter. Carbon 15-21 solute carrier family 6 member 3 Homo sapiens 108-128 11277529-2 2001 Methoxylation at the two-carbon bridge of benztropine produced a novel class of potent and selective DAT ligands. Carbon 25-31 solute carrier family 6 member 3 Homo sapiens 101-104 11322734-5 2001 Reactivity of the polysaccharide C-atoms was determined by 13C NMR spectroscopy: For dextran this was C-3 > C-2 > C-4, while for pullulan it was C-6 > C-3 > C-2 > C-4. Carbon 33-34 complement C3 Homo sapiens 102-105 10556795-7 1999 It is postulated that the increased dissimilation of the carbon substrate by lon-deficient Bl21(DE3) cells synthesizing the proteolytically unstable protein may result from a higher energy demand required for the in vivo degradation of this protein by ATP-dependent proteases different from the protease Lon. Carbon 57-63 lon peptidase 1, mitochondrial Homo sapiens 77-80 11322734-5 2001 Reactivity of the polysaccharide C-atoms was determined by 13C NMR spectroscopy: For dextran this was C-3 > C-2 > C-4, while for pullulan it was C-6 > C-3 > C-2 > C-4. Carbon 33-34 complement C3 Homo sapiens 160-163 11345253-5 2001 Good agreement is found for the band positions of carbon chains containing odd C15-C21 neutrals and even C6(-)-C22- anions, with species previously identified by Maier and coworkers using mass selection or laser vaporization, followed by neon matrix isolation. Carbon 50-56 placenta associated 8 Homo sapiens 79-82 10556795-7 1999 It is postulated that the increased dissimilation of the carbon substrate by lon-deficient Bl21(DE3) cells synthesizing the proteolytically unstable protein may result from a higher energy demand required for the in vivo degradation of this protein by ATP-dependent proteases different from the protease Lon. Carbon 57-63 lon peptidase 1, mitochondrial Homo sapiens 304-307 10204352-7 1998 Decline in beta 2-MG concentration in columns with engrafted and matrix carbon at the start of the perfusion and its rise during the second half of the session might be caused by blood cells structural and functional condition as a result of their interaction with the sorbent in question. Carbon 72-78 beta-2-microglobulin Homo sapiens 11-20 11181060-2 2001 When a carbon nanotube (CNT) tip was used, AFM images visualized the 10-nm pitch of RecA-dsDNA complexes and RecA filaments as three-dimensional surface topography without reconstruction analysis. Carbon 7-13 RAD51 recombinase Homo sapiens 84-88 11181060-2 2001 When a carbon nanotube (CNT) tip was used, AFM images visualized the 10-nm pitch of RecA-dsDNA complexes and RecA filaments as three-dimensional surface topography without reconstruction analysis. Carbon 7-13 RAD51 recombinase Homo sapiens 109-113 12083967-1 2001 5,10-Methylenetetrahydrofolate reductase (MTHFR) plays a key role in folate metabolism by channeling one-carbon units between nucleotide synthesis and methylation reactions. Carbon 105-111 methylenetetrahydrofolate reductase Homo sapiens 0-40 12083967-1 2001 5,10-Methylenetetrahydrofolate reductase (MTHFR) plays a key role in folate metabolism by channeling one-carbon units between nucleotide synthesis and methylation reactions. Carbon 105-111 methylenetetrahydrofolate reductase Homo sapiens 42-47 9894915-1 1998 The product of the ACR1 gene is essential for growth of Saccharomyces cerevisiae on ethanol or acetate as sole carbon source, and its expression is subject to glucose repression. Carbon 111-117 Arr1p Saccharomyces cerevisiae S288C 19-23 11542820-1 1998 A new 2.8-3.8 micrometers spectrum of the carbon-rich protoplanetary nebula CRL 618 confirms the previous detection of a circumstellar 3.4 micrometers absorption feature in this object (Lequeux & Jourdain de Muizon). Carbon 42-48 interleukin 31 receptor A Homo sapiens 76-79 11777394-2 2001 With the presence of 10 wt % palladium on activated carbon as the catalyst, the condensations between BDSB and diol-terminated PCL macromonomers having molecular weights of 1200, 2010, and 5500 g/mol were performed in toluene at 100 degrees C under argon. Carbon 52-58 PHD finger protein 1 Homo sapiens 127-130 9757554-5 1998 Similarly, hydrolysis of T-2 at the carbon-8 (C-8) position to neosolaniol strongly diminished its ability to induce DNA fragmentation. Carbon 36-42 brachyury 2 Mus musculus 25-28 11084289-9 2000 Addition of Fe(2+) under anaerobic conditions to an aqueous suspension of linoleic acid hydroperoxide and the spin trap resulted in the detection of three different species: a carbon-centered radical adduct, an acyl radical adduct, and the hydroxyl adduct. Carbon 176-182 spindlin 1 Homo sapiens 110-114 9660787-3 1998 To establish how it is glycosylated, SKP1 labeled with [3H]Fuc was purified to homogeneity and digested with endo-Lys-C. Carbon 118-119 S-phase kinase associated protein 1 Homo sapiens 37-41 11028635-1 2000 A novel tyrosinase biosensor has been developed for the subnanomolar detection of phenols, based on the immobilization of tyrosinase in a positively charged Al2O3 sol-gel membrane on a glassy carbon electrode. Carbon 192-198 tyrosinase Homo sapiens 122-132 10099331-7 1998 Two- to three-fold lower expression of the CDC28-lacZ fusion gene was detected in the snf1 or snf4 disruptants with respect to the WT and mig1 strains in the presence of all carbon sources. Carbon 174-180 cyclin-dependent serine/threonine-protein kinase CDC28 Saccharomyces cerevisiae S288C 43-53 11033414-4 2000 When mixed micelles of 16:0p/20:4-GPC were treated with Cu(II)/H(2)O(2), oxidation of the arachidonate esterified to the plasmalogen glycerophosphocholine lipid resulted in the most abundant products oxidized at carbon-5 of esterified arachidonate, but free carboxylic acid products were not formed. Carbon 212-218 glycophorin C (Gerbich blood group) Homo sapiens 34-37 11465082-5 2000 Human FMO3 is sensitive to steric features of the substrate and aliphatic amines with linkages between the nitrogen atom and a large aromatic group such as a phenothiazine of at least five carbons are N-oxygenated significantly more efficiently than those substrates with two or three carbons. Carbon 189-196 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 6-10 11465082-5 2000 Human FMO3 is sensitive to steric features of the substrate and aliphatic amines with linkages between the nitrogen atom and a large aromatic group such as a phenothiazine of at least five carbons are N-oxygenated significantly more efficiently than those substrates with two or three carbons. Carbon 285-292 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 6-10 9667976-1 1998 The development of novel monobactam inhibitors of HCMV protease incorporating a carbon side chain at C-4 and a urea function at N-1 is described. Carbon 80-86 complement C4A (Rodgers blood group) Homo sapiens 101-104 10882510-3 2000 The extent of reaction of p-nitrophenyl myristate, an ester with a linear acyl carbon chain length of 14, can be viewed as a probe to study the adhesion of the PDE/ester coaggregates to the cuvette surfaces. Carbon 79-85 aldehyde dehydrogenase 7 family member A1 Homo sapiens 160-163 19417509-0 2009 Functional single-walled carbon nanotubes based on an integrin alpha v beta 3 monoclonal antibody for highly efficient cancer cell targeting. Carbon 25-31 integrin subunit alpha V Homo sapiens 54-77 19250646-4 2009 Amperometric measurements based on carbon fiber microelectrodes demonstrated that PKC alpha has a key role in the PMA-mediated facilitation of exocytosis and vesicle fusion in neuroendocrine PC12 cells. Carbon 35-41 protein kinase C, alpha Rattus norvegicus 82-91 9660190-8 1998 The nikC-inactivated mutant grew with L-lysine as sole source of nitrogen and carbon, indicating that L-lysine 2-aminotransferase is not required for lysine catabolism. Carbon 78-84 relaxosome accessory protein Escherichia coli 4-8 19054362-3 2009 The fnr2 plants resembled fnr1 in having downregulated photosynthetic properties, expressed as low chlorophyll content, low accumulation of photosynthetic thylakoid proteins and reduced carbon fixation rate when compared with wild type (WT). Carbon 186-192 ferredoxin-NADP[+]-oxidoreductase 2 Arabidopsis thaliana 4-8 10864765-3 2000 This change of mechanism was justified on the basis of the syn and anti rotational conformers of the diene -N((1))=C-C=N((2))- group; the greater stability of the former can be explained by the formation of hydrogen bonds between the proton and the N((1)) and N((2)) nitrogen atoms, giving rise to a very stable five-membered ring. Carbon 115-116 synemin Homo sapiens 59-62 10841761-3 2000 In this study, we investigated the pH titration behavior of the carboxyl groups of the N-terminal domain of rat CD2 (CD2d1) using the chemical shifts of backbone amide nitrogen-15 ((15)N) and proton NMR resonances, and carboxyl carbon-13 ((13)C) signals. Carbon 228-234 Cd2 molecule Rattus norvegicus 112-115 10841761-3 2000 In this study, we investigated the pH titration behavior of the carboxyl groups of the N-terminal domain of rat CD2 (CD2d1) using the chemical shifts of backbone amide nitrogen-15 ((15)N) and proton NMR resonances, and carboxyl carbon-13 ((13)C) signals. Carbon 228-234 Cd2 molecule Rattus norvegicus 117-122 19225510-0 2009 Carbon cycle: Sink in the African jungle. Carbon 0-6 tribbles pseudokinase 3 Homo sapiens 14-18 9556588-4 1998 Steady state, photon counting fluorescence spectroscopy directly established that rat liver ACBP bound 18-carbon cis- and trans-parinaroyl-CoA, Kd = 7.03 +/- 0.95 and 4.40 +/- 0.43 nM. Carbon 106-112 diazepam binding inhibitor Rattus norvegicus 92-96 10781559-8 2000 The only growth phenotype observed was a longer lag time during growth on nonfermentable carbon sources in minimal media for the mis1 deletion strain but not for the fmt1 deletion strain. Carbon 89-95 trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase MIS1 Saccharomyces cerevisiae S288C 129-133 10757974-9 2000 This suggests that the role of the T-protein is not only to locate the tetrahydrofolate cofactor in a position favorable for a nucleophilic attack on the methylene carbon but also to destabilize the H-protein in order to facilitate the unlocking of the arm and initiate the reaction. Carbon 164-170 myosin binding protein H Homo sapiens 199-208 9566913-0 1998 Carbon source-dependent phosphorylation of hexokinase PII and its role in the glucose-signaling response in yeast. Carbon 0-6 hexokinase Saccharomyces cerevisiae S288C 43-53 18679731-1 2009 Phenylalanine ammonia-lyase and cinnamate 4-hydroxylase are important enzymes in allocating significant amounts of carbon from phenylalanine into the biosynthesis of several important secondary metabolites. Carbon 115-121 peptidylglycine alpha-amidating monooxygenase Homo sapiens 0-27 19322541-5 2009 Moreover, the first steps toward pretreatment stratification have been established by defining the role of MGMT-promotor methylation for treatment response and outcome.Over the last few years, particle therapy with protons and carbon ions has become available. Carbon 227-233 O-6-methylguanine-DNA methyltransferase Homo sapiens 107-111 9566913-6 1998 The reversible phosphorylation of Hxk2p is carbon source dependent, being more extensive on poor carbon sources such as galactose, raffinose, and ethanol. Carbon 43-49 hexokinase 2 Saccharomyces cerevisiae S288C 34-39 10798523-5 2000 Conformational searches located some low energy conformations that contained relatively short oxygen to carbonyl carbon distances, which indicated that the oxazole forming fragment in microcin B17 is preorganized for cyclization. Carbon 104-110 NADH:ubiquinone oxidoreductase subunit B6 Homo sapiens 193-196 9566913-6 1998 The reversible phosphorylation of Hxk2p is carbon source dependent, being more extensive on poor carbon sources such as galactose, raffinose, and ethanol. Carbon 97-103 hexokinase 2 Saccharomyces cerevisiae S288C 34-39 9576798-10 1998 The coordination of N and C metabolism is retained during drought conditions via modulation of the activities of Suc phosphate synthase and NR commensurate with the prevailing rate of photosynthesis. Carbon 16-17 nitrate reductase [NADH] 1 Zea mays 141-143 10744775-4 2000 The decrease in LCAT activity was significantly correlated with a decrease in rHDL fluidity (measured by diphenylhexatriene fluorescence polarization) for PC species containing 18 carbon (r(2) = 0.61, n = 18) and 20 carbon (r(2) = 0.93, n = 5) sn-2 fatty acyl chains. Carbon 180-186 lecithin-cholesterol acyltransferase Homo sapiens 16-20 10744775-4 2000 The decrease in LCAT activity was significantly correlated with a decrease in rHDL fluidity (measured by diphenylhexatriene fluorescence polarization) for PC species containing 18 carbon (r(2) = 0.61, n = 18) and 20 carbon (r(2) = 0.93, n = 5) sn-2 fatty acyl chains. Carbon 216-222 lecithin-cholesterol acyltransferase Homo sapiens 16-20 27873995-0 2008 Conformational Mobility of GOx Coenzyme Complex on Single-Wall Carbon Nanotubes. Carbon 63-69 hydroxyacid oxidase 1 Homo sapiens 27-30 19078857-3 2008 The absolute configuration of the newly created chiral carbon center (C-3) was assigned by X-ray diffraction analysis of the intermediate 3(S)-isothiocyanato-D-glycero-D-galacto-decose 8a. Carbon 55-61 complement C3 Homo sapiens 70-73 10763851-7 2000 Structure activity analyses of these data identified the requirement of a hydrophobic group connected to a 2-aminocarbonyl piperazine by a 5-carbon chain for high-affinity interactions with es/ENT1. Carbon 114-120 solute carrier family 29 (nucleoside transporters), member 1 Mus musculus 193-197 9604206-4 1998 In contrast to LAR isoforms without LASE-c, levels of LAR transcripts and protein isoforms containing LASE-c were primarily present during development, suggesting a mechanism for developmental regulation of LAR function. Carbon 3-4 low antibody response Mus musculus 54-57 18973310-0 2008 Alternate layer-by-layer adsorption of single- and double-walled carbon nanotubes wrapped by functionalized beta-1,3-glucan polysaccharides. Carbon 65-71 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 108-116 18973310-3 2008 These ionic beta-1,3-glucans wrap around single-walled carbon nanotubes (SWNTs) and double-walled carbon nanotubes (DWNTs) to form water-soluble complexes with ionic groups on their exterior surface. Carbon 55-61 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 12-20 10741962-0 2000 Global carbon sinks and their variability inferred from atmospheric O2 and delta13C. Carbon 7-13 immunoglobulin kappa variable 1D-39 Homo sapiens 68-83 18973310-3 2008 These ionic beta-1,3-glucans wrap around single-walled carbon nanotubes (SWNTs) and double-walled carbon nanotubes (DWNTs) to form water-soluble complexes with ionic groups on their exterior surface. Carbon 98-104 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 12-20 10741962-5 2000 The general agreement of the independent estimates from O2 and delta13C is a robust signal of variable carbon uptake by both the land biosphere and the oceans. Carbon 103-109 immunoglobulin kappa variable 1D-39 Homo sapiens 56-71 9604206-4 1998 In contrast to LAR isoforms without LASE-c, levels of LAR transcripts and protein isoforms containing LASE-c were primarily present during development, suggesting a mechanism for developmental regulation of LAR function. Carbon 3-4 low antibody response Mus musculus 54-57 18640024-2 2008 Pd/CNFs modified carbon paste electrode (Pd/CNF-CPE) displayed excellent electrochemical catalytic activities towards dopamine (DA), uric acid (UA) and ascorbic acid (AA). Carbon 17-23 NPHS1 adhesion molecule, nephrin Homo sapiens 3-6 9618218-4 1998 In contrast to LAR isoforms without LASE-c, levels of LAR transcripts and protein isoforms containing LASE-c were primarily present during development, suggesting a mechanism for developmental regulation of LAR function. Carbon 3-4 low antibody response Mus musculus 54-57 18774285-6 2008 By mimicking the complete citric acid cycle on a carbon electrode, power density was increased 8.71-fold compared to a single enzyme (alcohol dehydrogenase)-based ethanol/air biofuel cell. Carbon 49-55 aldo-keto reductase family 1 member A1 Homo sapiens 134-155 11017299-0 2000 Carbon nanotube based magnetic tunnel junctions Spin-coherent quantum transport in carbon nanotube magnetic tunnel junctions is investigated theoretically. Carbon 83-89 spindlin 1 Homo sapiens 48-52 9618218-4 1998 In contrast to LAR isoforms without LASE-c, levels of LAR transcripts and protein isoforms containing LASE-c were primarily present during development, suggesting a mechanism for developmental regulation of LAR function. Carbon 3-4 low antibody response Mus musculus 54-57 20641813-0 2004 Cyclic Arg-Gly-Asp-polyethyleneglycol-single-walled carbon nanotubes The alphaupsilonbeta3 integrin, also known as the vitronectin receptor, is a heterodimeric transmembrane glycoprotein found on most cells originating from mesenchyme (1). Carbon 52-58 vitronectin Homo sapiens 119-130 10683205-3 2000 The "cut-off" (alcohols with four carbons) displayed by the n-alkanols on GLYT2a indicates that a specific binding site for ethanol exists on GLYT2a or on a GLYT2a-interacting protein. Carbon 34-41 glycoprotein alpha-galactosyltransferase 1 (inactive) Homo sapiens 74-79 9525277-5 1998 GSTP1-1/V-105 was found to be more active than GSTP1-1/I-105 in conjugation reactions with the bulky diol epoxides of PAH, being up to 3-fold as active towards the anti- and syn-diol epoxide enantiomers with R-absolute configuration at the benzylic oxiranyl carbon. Carbon 258-264 glutathione S-transferase pi 1 Homo sapiens 0-7 10581437-13 2000 For all carbon sources, the DBT removal rate was faster and the HBP generation rate slower with the expression of the oxidoreductase. Carbon 8-14 oxidoreductase Escherichia coli 118-132 18579451-4 2008 The efficacy of this linking strategy is assessed using two model enzymes, glucose oxidase (GOx) and alcohol dehydrogenase (ADH), self-assembled onto separate nanoelectrode regions comprised of a highly ordered carbon nanotube (CNT) array. Carbon 211-217 hydroxyacid oxidase 1 Homo sapiens 75-90 18579451-4 2008 The efficacy of this linking strategy is assessed using two model enzymes, glucose oxidase (GOx) and alcohol dehydrogenase (ADH), self-assembled onto separate nanoelectrode regions comprised of a highly ordered carbon nanotube (CNT) array. Carbon 211-217 hydroxyacid oxidase 1 Homo sapiens 92-95 9420077-3 1998 METHODS: This laser catheter is fitted with an atraumatic ball-shaped fiber tip that is pretreated with a layer of carbon particles. Carbon 115-121 TOR signaling pathway regulator Homo sapiens 76-79 18713667-5 2008 The behavior of the tert-butoxyl radical mediated oxidation of MPTP contrasts with this reaction as catalyzed by monoamine oxidase B (MAO-B) that occurs selectively at the allylic alpha-carbon. Carbon 186-192 monoamine oxidase B Homo sapiens 113-132 18713667-5 2008 The behavior of the tert-butoxyl radical mediated oxidation of MPTP contrasts with this reaction as catalyzed by monoamine oxidase B (MAO-B) that occurs selectively at the allylic alpha-carbon. Carbon 186-192 monoamine oxidase B Homo sapiens 134-139 10618388-2 2000 Carbon fiber microelectrodes were used to measure individual secretory events of histamine and 5-hydroxytryptamine (5-HT) from VMAT2-expressing mast cells as a model system for quantal release. Carbon 0-6 solute carrier family 18 (vesicular monoamine), member 2 Mus musculus 127-132 10923034-1 2000 Methylenetetrahydrofolate reductase (MTHFR) catalyses the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a carbon donor for homocysteine remethylation to methionine. Carbon 133-139 methylenetetrahydrofolate reductase Homo sapiens 0-35 9420077-5 1998 As the heat is generated in this very thin layer of carbon coating, the temperature at the surface of the ball-shaped tip reaches ablative temperatures instantly at powers of only a few watts per second, which has enabled the authors to limit drastically the amount of laser light used and the length of exposure needed, thereby increasing safety even around critical structures. Carbon 52-58 TOR signaling pathway regulator Homo sapiens 118-121 10923034-1 2000 Methylenetetrahydrofolate reductase (MTHFR) catalyses the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a carbon donor for homocysteine remethylation to methionine. Carbon 133-139 methylenetetrahydrofolate reductase Homo sapiens 37-42 18795165-0 2008 Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells. Carbon 16-22 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 77-81 10176576-0 1997 Exempt distribution of a radioactive drug containing one microcurie of carbon-14 urea--NRC. Carbon 71-77 nuclear receptor coactivator 6 Homo sapiens 87-90 18667581-7 2008 The carbon- and NaCl-mediated transcriptional activation of ENA1 is dependent on Nsf1. Carbon 4-10 Na(+)/Li(+)-exporting P-type ATPase ENA1 Saccharomyces cerevisiae S288C 60-64 18648547-6 2008 We then produced a fully atomistic model of a homotypic Cx32 connexon starting from a published model of the C alpha carbons arrangement for the connexin transmembrane helices, to which we added extracellular and cytoplasmic loops. Carbon 117-124 gap junction protein beta 1 Homo sapiens 56-60 10608811-1 1999 ADR1 encodes a transcriptional activator that regulates genes involved in carbon source utilization in Saccharomyces cerevisiae. Carbon 74-80 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 0-4 10585550-5 1999 Ethanol as a carbon source or addition of 1 M NaCl with glucose as the carbon source in the growth medium increased beta-galactosidase activity from an ALD5-lacZ fusion. Carbon 71-77 aldehyde dehydrogenase (NAD(P)(+)) ALD5 Saccharomyces cerevisiae S288C 152-156 9362486-0 1997 Disruption of the plastid ycf10 open reading frame affects uptake of inorganic carbon in the chloroplast of Chlamydomonas. Carbon 79-85 envelope membrane protein Chlamydomonas reinhardtii 26-31 10628872-1 1999 The yeast transcriptional activator Cat8p has been identified as a factor that is essential for the derepression of genes involved in gluconeogenesis (like FBP1, PCK1, ACR1, ICL1 and MLS1) when only nonfermentable carbon sources are provided. Carbon 214-220 malate synthase MLS1 Saccharomyces cerevisiae S288C 183-187 18339532-4 2008 Immobilization of enzyme onto the carbon post-electrodes was carried out through co-deposition of glucose oxidase (GOx) and electrochemically polymerized polypyrrole (PPy). Carbon 34-40 hydroxyacid oxidase 1 Homo sapiens 98-113 18339532-4 2008 Immobilization of enzyme onto the carbon post-electrodes was carried out through co-deposition of glucose oxidase (GOx) and electrochemically polymerized polypyrrole (PPy). Carbon 34-40 hydroxyacid oxidase 1 Homo sapiens 115-118 9390453-4 1997 C-105 and other gcr1 cat mutants do not grow on methanol medium without an alternative carbon source. Carbon 87-93 transcription regulator GCR1 Saccharomyces cerevisiae S288C 16-20 18559150-5 2008 Comparison of the experimental spectra in a data set to spectra calculated from the pure components derived by least squares modeling gave an excellent match for bands of the -CF2 and C-O-C group modes, but agreement was not as close for bands arising from modes of the hydrophilic -SO3(-) group and (modeled separately) water. Carbon 0-1 ATPase H+ transporting accessory protein 1 Homo sapiens 176-179 10567344-2 1999 We found that mouse Cdk5 kinase produced in pho85Delta mutant cells could suppress some of pho85Delta mutant phenotypes including failure to grow on nonfermentable carbon sources, morphological defects, and growth defect caused by Pho4 or Clb2 overproduction. Carbon 164-170 cyclin-dependent kinase 5 Mus musculus 20-24 9390453-6 1997 These Mth+ gcr1 cat scd strains utilize methanol as a sole source of carbon and energy, although biomass yields are reduced relative to the wild-type strain. Carbon 69-75 transcription regulator GCR1 Saccharomyces cerevisiae S288C 11-15 9353925-3 1997 Upon exposure to high-osmolarity stress, the kinetics of induction of HSP12 in cells growing on the non-fermentable carbon sources are strikingly different from those on glucose. Carbon 116-122 lipid-binding protein HSP12 Saccharomyces cerevisiae S288C 70-75 10536147-0 1999 Expression of GUT1, which encodes glycerol kinase in Saccharomyces cerevisiae, is controlled by the positive regulators Adr1p, Ino2p and Ino4p and the negative regulator Opi1p in a carbon source-dependent fashion. Carbon 181-187 transcriptional regulator OPI1 Saccharomyces cerevisiae S288C 170-175 10565290-2 1999 The incorporation of the natural oxygen binder myoglobin into a GOx-containing carbon-paste matrix is shown to satisfy the oxygen demand of the enzymatic reaction and to provide convenient biosensing of glucose in oxygen-free solutions. Carbon 79-85 hydroxyacid oxidase 1 Homo sapiens 64-67 10508110-3 1999 Strains TA5 and TA27 could degrade 25 and 75 mg. liter of TCA(-1) cometabolically in the presence of ethane as a carbon source, respectively. Carbon 113-119 trace amine associated receptor 8 Homo sapiens 8-11 17674125-10 2008 Co-composting experiments with fats and cellulose presented higher initial C/N ratio and lower nitrogen losses, 27.5 and 34.2% compared to 40% for raw sludge. Carbon 0-1 chromosome 10 open reading frame 90 Homo sapiens 31-35 18589954-3 2008 Results from experiments with both 14C-RDX and LC-MS analysis indicate that the remaining carbon products are soluble and most likely small (< 50 Da). Carbon 90-96 radixin Homo sapiens 39-42 18338327-4 2008 It is shown that the (13)C resonances of C-6, C-7 and C-11 carbon atoms are suitable for distinguishing between the tautomeric forms of aza-derivatives of gossypol in the solid state. Carbon 25-26 complement C7 Homo sapiens 46-49 18493652-2 2008 We synthesized palmitic acid with carbons C-3 through C-16 perdeuterated, C-1 and C-2 with 13C atoms and hydrogens at C-2. Carbon 34-41 complement C3 Homo sapiens 42-45 9353925-4 1997 Derepression of HSP12 gene expression under non-stress conditions was observed in cells growing on non-fermentable carbon sources. Carbon 115-121 lipid-binding protein HSP12 Saccharomyces cerevisiae S288C 16-21 10471404-7 1999 A mass difference of 184.0 +/- 0.2 Da was observed on MALDI between (13)C-labeled peptide P1 and P2, indicating six carbons in the modification group. Carbon 116-123 crystallin gamma F, pseudogene Homo sapiens 90-99 9278857-2 1997 Addition of double and triple bonds to the C/D ring (C-16) and side chain (C-22 and C-23) as well as lengthening of the side chain were important for enhanced activity against LNCaP and PC-3. Carbon 43-44 chromobox 8 Homo sapiens 186-190 10451381-5 1999 Both proton and carbon NMR data are consistent with a syn glycosidic torsion angle for the [AP]dG6 residue in the adduct duplex. Carbon 16-22 synemin Homo sapiens 54-57 18417639-3 2008 In a screen for genes whose expression was altered in response to the induction of AP3 activity, we identified GNC (GATA, nitrate-inducible, carbon-metabolism-involved) as being negatively regulated by AP3 and PI. Carbon 141-147 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 116-120 18417639-4 2008 The GNC gene encodes a member of the Arabidopsis GATA transcription factor family and has been implicated in the regulation of chlorophyll biosynthesis as well as carbon and nitrogen metabolism. Carbon 163-169 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 49-53 9278857-2 1997 Addition of double and triple bonds to the C/D ring (C-16) and side chain (C-22 and C-23) as well as lengthening of the side chain were important for enhanced activity against LNCaP and PC-3. Carbon 53-54 chromobox 8 Homo sapiens 186-190 10441143-8 1999 When comparing the specificity of SULT1A3 toward tyramine with that for p-ethylphenol (which differs from tyramine in having no amine group on the carbon side chain), we saw a 200-fold preference for tyramine. Carbon 147-153 sulfotransferase family 1A member 3 Homo sapiens 34-41 9224895-3 1997 PCK1 transcript levels were efficiently repressed by glucose and derepressed (induced) on gluconeogenetic carbon sources. Carbon 106-112 phosphoenolpyruvate carboxykinase PCK1 Saccharomyces cerevisiae S288C 0-4 10941798-1 1999 Denitrifying strain EbN1 utilizes either ethylbenzene or toluene as the sole source of organic carbon under strictly anoxic conditions. Carbon 95-101 potassium voltage-gated channel subfamily Q member 2 Homo sapiens 20-24 21202713-1 2008 In the title compound, C(8)H(8)ClNO, the conformations of the N-H and C=O bonds are anti to each other, but the C-Cl and C=O bonds in the side chain are syn. Carbon 23-24 synemin Homo sapiens 153-156 9225860-2 1997 Clones were sought which restored the ability of pas9 cells to grow on oleate as a sole carbon source, as oleate metabolism requires peroxisomal beta-oxidation and therefore functional peroxisomes. Carbon 88-94 Pex17p Saccharomyces cerevisiae S288C 49-53 17645476-11 2008 The distribution of haplotypes of IL-10-1117 and IL-10-627 was A-A (69%), A-C (26%), and G-C (5%). Carbon 76-77 interleukin 10 Homo sapiens 34-39 10207058-3 1999 This report demonstrates that Ume3p levels are also reduced in cultures subjected to ethanol shock, oxidative stress, or carbon starvation or during growth on nonfermentable carbons. Carbon 121-127 cyclin-dependent protein serine/threonine kinase regulator SSN8 Saccharomyces cerevisiae S288C 30-35 10207058-3 1999 This report demonstrates that Ume3p levels are also reduced in cultures subjected to ethanol shock, oxidative stress, or carbon starvation or during growth on nonfermentable carbons. Carbon 174-181 cyclin-dependent protein serine/threonine kinase regulator SSN8 Saccharomyces cerevisiae S288C 30-35 9197408-3 1997 The Zn(II)2Cys6 cluster shows strong similarity with those of the Saccharomyces cerevisiae carbon metabolism regulatory proteins CAT8 and SIP4. Carbon 91-97 DNA-binding transcription factor CAT8 Saccharomyces cerevisiae S288C 129-133 11674159-0 1999 Stereochemical Determination of Acyclic Structures Based on Carbon-Proton Spin-Coupling Constants. Carbon 60-66 spindlin 1 Homo sapiens 74-78 18518136-0 2008 Electrically tunable spin polarization in a carbon nanotube spin diode. Carbon 44-50 spindlin 1 Homo sapiens 21-25 18518136-0 2008 Electrically tunable spin polarization in a carbon nanotube spin diode. Carbon 44-50 spindlin 1 Homo sapiens 60-64 11671719-7 1997 The Rh(II)-catalyzed reaction of 3 ("carbon" analog of 2a) resulted mainly in the cyclopentanone derivative, and no cyclopropanation product was detected. Carbon 37-43 Rh blood group D antigen Homo sapiens 4-10 18572597-1 2008 Direct reaction of herringbone, platelet, or narrow, tubular herringbone graphitic carbon nanofibers (GCNFs) with molten potassium gives K/GCNF intercalates with stoichiometric control of potassium loading. Carbon 83-89 nuclear receptor subfamily 6 group A member 1 Homo sapiens 102-106 17706456-0 2008 Spin probe ESR studies of dynamics of single walled carbon nanotubes. Carbon 52-58 spindlin 1 Homo sapiens 0-4 10231390-5 1999 RESULTS: When COF1 was over-expressed in yeast cells under the GAL1 promoter in a medium containing galactose as a sole carbon source, the cells did not survive. Carbon 120-126 cofilin Saccharomyces cerevisiae S288C 14-18 11669778-7 1997 For cob(II)inamide itself, the alpha diastereomer is enthalpically stabilized relative to the beta diastereomer in the transition state for carbon-cobalt bond formation, but an even larger entropic stabilization of the beta diastereomer causes the latter to be the predominant product. Carbon 140-146 metabolism of cobalamin associated B Homo sapiens 4-7 9867807-8 1999 Deletion of the ATP18 gene encoding Su j led to a strain (Deltasu j) completely deficient in oligomycin-sensitive ATPase activity and unable to grow on nonfermentable carbon sources. Carbon 167-173 F1F0 ATP synthase subunit i Saccharomyces cerevisiae S288C 16-21 9858577-3 1999 Analysis of the ENA1 promoter revealed a Mig1p-binding motif (-533 to -544) which was characterized as an upstream repressing sequence (URSMIG-ENA1) regulated by carbon source. Carbon 162-168 Na(+)/Li(+)-exporting P-type ATPase ENA1 Saccharomyces cerevisiae S288C 16-20 17706456-1 2008 The highly sensitive technique of spin-probe Electron Spin Resonance (ESR) has been used to study dynamics of carbon nanotubes. Carbon 110-116 spindlin 1 Homo sapiens 34-38 17706456-1 2008 The highly sensitive technique of spin-probe Electron Spin Resonance (ESR) has been used to study dynamics of carbon nanotubes. Carbon 110-116 spindlin 1 Homo sapiens 54-58 18056926-6 2008 Treatment with t-10, c-12 CLA reduced TG as well as cellular and secreted adiponectin levels and impaired the assembly of adiponectin oligomers. Carbon 21-22 clasper Mus musculus 26-29 17891379-6 2008 We conclude that the Lon protease supports survival during anaerobic carbon starvation by a mechanism which does not depend on Clp. Carbon 69-75 putative ATP-dependent Lon protease Escherichia coli 21-24 9858577-3 1999 Analysis of the ENA1 promoter revealed a Mig1p-binding motif (-533 to -544) which was characterized as an upstream repressing sequence (URSMIG-ENA1) regulated by carbon source. Carbon 162-168 Na(+)/Li(+)-exporting P-type ATPase ENA1 Saccharomyces cerevisiae S288C 136-147 11542489-3 1998 The Mir-1997 flight sample showed higher C/N ratio probably because of the dissolution of carbon-rich plant materials. Carbon 90-96 membrane associated ring-CH-type finger 8 Homo sapiens 4-7 9143345-5 1997 Bovine lens SDH is active on polyalcohols and keto-sugars with more than three carbon atoms, and also requires special steric constraints for substrate recognition. Carbon 79-85 serine dehydratase Bos taurus 12-15 9726882-3 1998 We found that the average contents of carbon and nitrogen for oceanic bacterial assemblages were 12.4 +/- 6.3 and 2.1 +/- 1.1 fg cell-1 (mean +/- standard deviation; n = 6), respectively. Carbon 39-45 carboxyl ester lipase pseudogene Homo sapiens 130-136 18613616-1 2008 The aim of this work was to isolate oil-degrading bacteria that use chitin or keratin as carbon sources from oil contaminated soils; and additionally to study if oil removal by these bacteria is enhanced when a chitinous or a keratinous waste is added to the culture media. Carbon 89-95 keratin Gallus gallus 78-85 18975195-1 1997 New HMG-CoA reductase inhibitors, in which 3-substituted 4,5-polymethylenepyrazoles are employed as a hydrophobic anchor connected to tetrahydro-4-hydroxy-2H-pyran-2-one by a two-carbon bridge, were designed and synthesized to exhibit significant inhibitory activity comparable to mevinolin. Carbon 179-185 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 4-21 18028974-7 2008 MEFs from nrf2(-/-) mice expressed less NQO1 mRNA than did wild-type MEFs, but NQO1 was induced modestly by coffee or C+K in the mutant fibroblasts. Carbon 118-119 NAD(P)H dehydrogenase, quinone 1 Mus musculus 79-83 9781839-7 1998 An analysis of the three-dimensional models of the compounds with the C-7 substituted, nitrogen-containing groups revealed that the range of the geometrically optimum distance between the nitrogen and the carbon atoms was from 2.98 to 4.98 A for highly active compounds and from 2.47 to 2.65 A for weakly active compounds. Carbon 205-211 complement C7 Canis lupus familiaris 70-73 9781839-8 1998 In conclusion, the C-7 substituted piperazine moiety of the molecules of already-known fluoroquinolone antibiotics may be responsible for the ability to increase cutaneous vascular permeability, whereas T-3762 is practically inactive because the free amino nitrogen of the 1-aminocyclopropyl group is conformationally present at a shorter distance from the carbon atom at position 7 of the ring nucleus. Carbon 357-363 complement C7 Canis lupus familiaris 19-22 9103982-0 1997 Growth of Escherichia coli in acetate as a sole carbon source is inhibited by ankyrin-like repeats present in the 2",5"-linked oligoadenylate-dependent human RNase L enzyme. Carbon 48-54 ribonuclease L Homo sapiens 158-165 9634475-8 1998 In particular, a GATA/c-Ets motive was identified in a short segment homologous to the mouse CD4 distal enhancer, suggesting that LAG-3, which is embedded in the CD4 locus, may be controlled by some CD4 regulatory elements. Carbon 8-9 CD4 antigen Mus musculus 93-96 9634475-8 1998 In particular, a GATA/c-Ets motive was identified in a short segment homologous to the mouse CD4 distal enhancer, suggesting that LAG-3, which is embedded in the CD4 locus, may be controlled by some CD4 regulatory elements. Carbon 8-9 CD4 antigen Mus musculus 162-165 9634475-8 1998 In particular, a GATA/c-Ets motive was identified in a short segment homologous to the mouse CD4 distal enhancer, suggesting that LAG-3, which is embedded in the CD4 locus, may be controlled by some CD4 regulatory elements. Carbon 8-9 CD4 antigen Mus musculus 162-165 18560610-3 2008 Under stress conditions and during growth in a nonfermentable carbon source Maf1 is dephosphorylated and imported to the nucleus. Carbon 62-68 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 76-80 18560610-7 2008 The absence of Maf1-mediated control of tRNA synthesis impairs yeast viability in nonfermentable carbon sources. Carbon 97-103 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 15-19 18560610-8 2008 Moreover, in cells grown in a nonfermentable carbon source, Maf1 regulates the levels of different tRNAs to various extents. Carbon 45-51 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 60-64 9103982-5 1997 Our findings demonstrate that E. coli expressing RNase L ankyrin repeats is unable to grow in medium containing acetate as the sole carbon source, while it can grow when expressing other domains of the protein. Carbon 132-138 ribonuclease L Homo sapiens 49-56 18600828-2 2008 The eight-membered B ring is formed by a ring-closing metathesis reaction (RCM) between the C10 and C11 carbon atoms. Carbon 104-110 aldo-keto reductase family 1 member C4 Homo sapiens 100-103 9020190-5 1997 These experiments show that two interrelated mechanisms are involved in the glucose repression of MAL62: 1) competition between the Mal63p activator and Mig1p for DNA binding and 2) modulation of Mig1p binding by the carbon source. Carbon 217-223 vacuolar protein sorting 4 homolog B Homo sapiens 196-201 18687588-5 2008 A. thaliana Atscp2-1 plants deficient in AtSCP2 show altered seed morphology, a delayed germination, and are dependent on an exogenous carbon source to avoid a delayed seedling establishment. Carbon 135-141 sterol carrier protein 2 Arabidopsis thaliana 12-18 18687588-5 2008 A. thaliana Atscp2-1 plants deficient in AtSCP2 show altered seed morphology, a delayed germination, and are dependent on an exogenous carbon source to avoid a delayed seedling establishment. Carbon 135-141 sterol carrier protein 2 Arabidopsis thaliana 41-47 9698817-11 1998 Lastly, the role of the alternative oxidase in non-thermogenic tissues is discussed in relation to the energy metabolism balance of the cell (supply in reducing equivalents/demand in energy and carbon) and with harmful reactive oxygen species formation. Carbon 194-200 acyl-CoA oxidase 1 Homo sapiens 24-43 9620972-0 1998 Effects of carbon source on expression of F0 genes and on the stoichiometry of the c subunit in the F1F0 ATPase of Escherichia coli. Carbon 11-17 ATPase Escherichia coli 105-111 9257126-3 1997 The results obtained are in agreement with a proposed mechanism for these reactions, involving nucleophilic attack of the mono-deprotonated peroxide species (HO2-) at the C-2 carbonyl group carbon centre. Carbon 175-181 complement C2 Homo sapiens 171-174 9570105-8 1998 One additional important source of AOX in hospital effluents may be x-ray contrast media containing a iodine carbon bond. Carbon 109-115 acyl-CoA oxidase 1 Homo sapiens 35-38 17936739-3 2007 Previous QM studies of 2-O-methyl substituted manno and gluco configured pyranosyl oxacarbenium ions found a preference for the methyl carbon to be syn to the CH-2 methine. Carbon 135-141 synemin Homo sapiens 148-151 8930899-8 1996 Platinum/carbon replicas of the fibroblast surface incubated either with lipoprotein lipase or antiheparan sulfate showed large aggregates of HSPGs regularly distributed along cytoplasmic fibers. Carbon 9-15 lipoprotein lipase Homo sapiens 73-91 18044868-5 2007 Unlike the GFP chromophore, the RFP chromophore model compound HBMPI in basic solution can only adopt a conformation where the C=C bond between the bridge group and the imidazolinone ring and the C-C bond between the imidazolinone and ethylene groups exist in cis and trans conformations, respectively. Carbon 127-128 tripartite motif containing 27 Homo sapiens 32-35 18044868-5 2007 Unlike the GFP chromophore, the RFP chromophore model compound HBMPI in basic solution can only adopt a conformation where the C=C bond between the bridge group and the imidazolinone ring and the C-C bond between the imidazolinone and ethylene groups exist in cis and trans conformations, respectively. Carbon 129-130 tripartite motif containing 27 Homo sapiens 32-35 18044868-5 2007 Unlike the GFP chromophore, the RFP chromophore model compound HBMPI in basic solution can only adopt a conformation where the C=C bond between the bridge group and the imidazolinone ring and the C-C bond between the imidazolinone and ethylene groups exist in cis and trans conformations, respectively. Carbon 129-130 tripartite motif containing 27 Homo sapiens 32-35 18026586-7 2007 By contrast PX3 and AsI3 coordinate to the CI3+ cations and the adducts have classical, carbon-bound ethane-like structures, as proven by X-ray single-crystal diffraction, IR, UV-Vis and NMR spectroscopy. Carbon 88-94 pannexin 3 Homo sapiens 12-15 21781864-4 1998 While human CYP1A1, rat CYP1A1 and rat CYP1A2 formed almost exclusively the (-)-B[c]Ph-3R,4R-dihydrodiol, human CYP1A2 produced both the (-)-3R,4R- and the (+)-3S,4S-dihydrodiol enantiomers in a ratio of 2:1. Carbon 62-63 cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus 39-45 9549626-3 1998 The presence of lipophagy, the number of foreign-body giant cells of histiocytic origin, and the number of MIB-1 positive nuclei (an index of proliferation for the reactive stromal population) were all seen to be influenced by the pyrolytic carbon coating. Carbon 241-247 MIB E3 ubiquitin protein ligase 1 Homo sapiens 107-112 9539701-1 1998 This review focuses on the monoterpene, sesquiterpene, and diterpene synthases of plant origin that use the corresponding C10, C15, and C20 prenyl diphosphates as substrates to generate the enormous diversity of carbon skeletons characteristic of the terpenoid family of natural products. Carbon 212-218 placenta associated 8 Homo sapiens 127-130 8900132-0 1996 Carbon source regulation of PIS1 gene expression in Saccharomyces cerevisiae involves the MCM1 gene and the two-component regulatory gene, SLN1. Carbon 0-6 transcription factor MCM1 Saccharomyces cerevisiae S288C 90-94 11667621-4 1996 Instead the ring is closed by a bond from the indole nitrogen of Trp-1 to the beta-carbon of Trp-2. Carbon 83-89 tRNA-Pro (anticodon AGG) 2-5 Homo sapiens 65-70 9613940-1 1998 The retention mechanism of guanidino compounds on a porous graphitic carbon seemed to be mainly hydrophobic interaction, according to the retention factors in buffer solutions and the results of an analysis by computational chemical calculation using molecular mechanics (MM2). Carbon 69-75 PNMA family member 2 Homo sapiens 272-275 17823857-7 2007 Moreover, (13)C-NMR data from a rat model of mild HE demonstrated relative differences in the pathway of glucose through pyruvate carboxylase in thalamus compared to frontal cortex, which might explain the vulnerability of this brain region compared to thalamus. Carbon 14-15 pyruvate carboxylase Rattus norvegicus 121-141 8923734-2 1996 Using a STA2-lacZ fusion it was found that: (1) the MIG1 gene is dispensable for the repression of the STA2 gene; (2) there are two components in the carbon-source repression of STA2: HXK2-dependent and HXK2-independent; and (3) the HAP2 gene seems to be involved in repression rather than activation of the STA2 expression. Carbon 150-156 hexokinase 2 Saccharomyces cerevisiae S288C 184-188 17967036-6 2007 These sulfite addition reactions, which are slowly reversible and are not catalyzed by the enzyme, result in the appearance of one (or, in the case of OMP, two) bulky anionic substituents at the 6-carbon atom of UMP. Carbon 197-203 olfactory marker protein Homo sapiens 151-154 9641570-6 1998 Marked linkage disequilibrium exists between the beta2-adrenoceptor polymorphisms at amino acid 16 and 27 (D=0.38, chi2 P<0.0001), and between the beta2-adrenoceptor polymorphisms at amino acid 27 and nucleic acid residue 523 (C-A) (D=0.36, chi2 P<0.0001). Carbon 230-231 adrenoceptor beta 2 Homo sapiens 49-67 9641570-6 1998 Marked linkage disequilibrium exists between the beta2-adrenoceptor polymorphisms at amino acid 16 and 27 (D=0.38, chi2 P<0.0001), and between the beta2-adrenoceptor polymorphisms at amino acid 27 and nucleic acid residue 523 (C-A) (D=0.36, chi2 P<0.0001). Carbon 230-231 adrenoceptor beta 2 Homo sapiens 150-168 11672041-1 1998 Oxidation of D-mannosamine (1), D-glucosamine (2), and D-galctosamine (3) by sodium N-chlorobenzenesulfonamide or chloramine-B (CAB) at 313 K is followed by a shortening of carbon chain and obeys the rate law, rate = k[CAB][sugar][HO(-)](x)(), where x is less than unity. Carbon 173-179 neural proliferation, differentiation and control 1 Homo sapiens 114-126 11672041-1 1998 Oxidation of D-mannosamine (1), D-glucosamine (2), and D-galctosamine (3) by sodium N-chlorobenzenesulfonamide or chloramine-B (CAB) at 313 K is followed by a shortening of carbon chain and obeys the rate law, rate = k[CAB][sugar][HO(-)](x)(), where x is less than unity. Carbon 173-179 neural proliferation, differentiation and control 1 Homo sapiens 128-131 8923734-2 1996 Using a STA2-lacZ fusion it was found that: (1) the MIG1 gene is dispensable for the repression of the STA2 gene; (2) there are two components in the carbon-source repression of STA2: HXK2-dependent and HXK2-independent; and (3) the HAP2 gene seems to be involved in repression rather than activation of the STA2 expression. Carbon 150-156 hexokinase 2 Saccharomyces cerevisiae S288C 203-207 9504777-5 1998 In biological samples, the Ca-L2,3 signal is superimposed on the carbon edge and artifacts may result from thickness and scattering effects. Carbon 65-71 carbonic anhydrase 3 Rattus norvegicus 27-34 8923734-2 1996 Using a STA2-lacZ fusion it was found that: (1) the MIG1 gene is dispensable for the repression of the STA2 gene; (2) there are two components in the carbon-source repression of STA2: HXK2-dependent and HXK2-independent; and (3) the HAP2 gene seems to be involved in repression rather than activation of the STA2 expression. Carbon 150-156 transcription activator HAP2 Saccharomyces cerevisiae S288C 233-237 17623847-1 2007 Citrate synthase is an archetypal carbon-carbon bond forming enzyme. Carbon 34-40 citrate synthase Sus scrofa 0-16 8679611-8 1996 Since the C14-C15 stretch mode frequency is relatively high in the spectra of octopus rhodopsin and bathorhodopsin (> 1200 cm-1) and since the normal mode pattern near the Schiff base is similar to the model, we suggest that the C=N configuration in these two species is anti. Carbon 10-11 rhodopsin Bos taurus 86-95 17623847-1 2007 Citrate synthase is an archetypal carbon-carbon bond forming enzyme. Carbon 41-47 citrate synthase Sus scrofa 0-16 17989465-1 2007 In the title complex, [Zn(C(12)H(6)O(4))(H(2)O)](n), a Zn(II) polymer based on naphthalene-1,8-dicarboxylate (1,8-nap), the Zn(II) atoms adopt an elongated octahedral coordination geometry. Carbon 26-27 catenin beta like 1 Homo sapiens 79-82 17924615-2 2007 The structures of two representative nonpolar metabolites were identified earlier as dimers of 17beta-estradiol linked through a diaryl ether bond between the C-3 phenolic oxygen of one molecule and the C-2 or C-4 aromatic carbon of another. Carbon 223-229 complement C3 Homo sapiens 159-162 11539572-4 1996 We find the abundance ratio of HCN:HCCN:HCCCN in TMC-l to be l : <0.01 : 0.3, which suggests that carbon-chain growth by the addition of single carbon atoms may not be efficient under dark cloud conditions. Carbon 101-107 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 31-34 17627857-8 2007 The central carbon atom C13 is sp(3) hybridized, which makes the non-planar molecule shape like a straw-hat. Carbon 12-18 homeobox C13 Homo sapiens 24-27 11539572-4 1996 We find the abundance ratio of HCN:HCCN:HCCCN in TMC-l to be l : <0.01 : 0.3, which suggests that carbon-chain growth by the addition of single carbon atoms may not be efficient under dark cloud conditions. Carbon 147-153 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 31-34 8657561-6 1996 Gel mobility shift analysis and in vitro DNase I footprinting have shown that proteins bind specifically to two downstream repressor sequences (DRS1 located from +140 to +163 and DRS2 located between +231 and +251) that influence the rate of HXK2 transcription when ethanol is used as carbon source by Saccharomyces cerevisiae. Carbon 285-291 hexokinase 2 Saccharomyces cerevisiae S288C 242-246 17785443-0 2007 Maf1 is involved in coupling carbon metabolism to RNA polymerase III transcription. Carbon 29-35 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 0-4 8608153-5 1996 Direct measurements of cellular folate coenzyme levels revealed substantial levels of 10-formyl-THF (CHO-THF), the one-carbon donor used in purine synthesis, in the purine-requiring ade3 deletion strain. Carbon 119-125 trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3 Saccharomyces cerevisiae S288C 182-186 17785443-5 2007 The transition from a nonfermentable carbon source to that of glucose induces Maf1 phosphorylation and its relocation to the cytoplasm. Carbon 37-43 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 78-82 17785443-6 2007 The absence of Maf1-mediated control of tRNA synthesis impairs cell viability in nonfermentable carbon sources. Carbon 96-102 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 15-19 17785443-8 2007 Moreover, in cells grown in a nonfermentable carbon source, Maf1 regulates the levels of different tRNAs to various extents. Carbon 45-51 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 60-64 8786078-1 1996 The conversion of serine and tetrahydrofolate to glycine and 5,10 methylene tetrahydrofolate by serine hydroxymethyltransferase (SHMT, EC 2.1.2.1) is the major route for the provision of one-carbon units for biosynthetic reactions. Carbon 191-197 serine hydroxymethyltransferase 1 Homo sapiens 96-127 18019147-2 2007 The complex dielectric constant of carbon tubes at various frequencies was measured by a resistance-inductance-capacitance (RLC) meter and a microwave network analyzer. Carbon 35-41 integrin subunit alpha 9 Homo sapiens 124-127 17467970-5 2007 The most efficient biosensors were those constructed by using the following composition for the carbon paste: 10% of tyrosinase, 45% of single wall carbon nanotubes (SWCN) and 45% of mineral oil. Carbon 96-102 tyrosinase Homo sapiens 117-127 8786078-1 1996 The conversion of serine and tetrahydrofolate to glycine and 5,10 methylene tetrahydrofolate by serine hydroxymethyltransferase (SHMT, EC 2.1.2.1) is the major route for the provision of one-carbon units for biosynthetic reactions. Carbon 191-197 serine hydroxymethyltransferase 1 Homo sapiens 129-133 17467970-7 2007 This experimental work represents a first attempt at construction of a new carbon nanotube-tyrosinase based biosensor able to determine the concentration of BPA, one of the most ubiquitous and hazardous endocrine disruptors which can pollute the drinking and surface water, as well as many products of the food chain. Carbon 75-81 tyrosinase Homo sapiens 91-101 8935632-12 1996 3) The type in which a cis-diaxial-diol side chain in the alpha side of C-16 and C-17 positions of the ring D or its ketal blocking group seems to be associated with the reaction. Carbon 72-73 cytokine like 1 Homo sapiens 81-85 17676909-5 2007 With 3,9-dimethyl (14), C-7 protonation (14H+) is strongly favored (with <10% protonation at C-12), and with 1,12-dimethyl (15) the sole species observed is the C-7 protonated carbocation (15H+). Carbon 24-25 complement C7 Homo sapiens 164-167 8654431-3 1996 Medium-chain fatty-acyl-CoA esters (10-14 carbons) inhibit Glc6Pase of untreated microsomes in a dose-dependent manner in the range 1-20 microM. Carbon 42-49 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 59-67 17893649-12 2007 In contrast, expression of HCCS E159K did not complement respiratory growth of the CYC3-deficient yeast strain B-8025, while wild-type HCCS and the yeast heme lyase Cyc3p could rescue growth on nonfermentable carbon sources. Carbon 209-215 holocytochrome c synthase CYC3 Saccharomyces cerevisiae S288C 165-170 17516558-8 2007 SMR analyses found an overall positive significant trend between lung cancer risks and cumulative carbon black exposure received in the most recent 15 years. Carbon 98-104 LY6/PLAUR domain containing 4 Homo sapiens 0-3 8654431-8 1996 Fatty-acyl-CoA esters with longer chain length (equal to or higher than 16 carbons) inhibit Glc6Pase of untreated microsomes within the range 1-2 microM. Carbon 75-82 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 92-100 8576067-1 1996 An alpha-amylase was purified from culture supernatants of Sulfolobus solfataricus 98/2 during growth on starch as the sole carbon and energy source. Carbon 124-130 glycoside hydrolase family 57 protein Saccharolobus solfataricus 98/2 3-16 8576067-7 1996 The absolute levels of alpha-amylase detected in culture supernatants varied greatly with the type of sole carbon source used to support growth. Carbon 107-113 glycoside hydrolase family 57 protein Saccharolobus solfataricus 23-36 8576067-8 1996 Aspartate was identified as the most repressing sole carbon source for alpha-amylase production, while glutamate was the most derepressing. Carbon 53-59 glycoside hydrolase family 57 protein Saccharolobus solfataricus 71-84 7589241-13 1995 This reflected the fact that EGF induced c-Fos accumulation in 90% of cells in the presence of forskolin but in 30-50% of cells in its absence. Carbon 10-11 epidermal growth factor Canis lupus familiaris 29-32 8750105-1 1995 A method is proposed for rapid and effective forming of the recording tips of carbon-fibre microelectrodes by trimming and treating the tip with electric current pulses. Carbon 78-84 TOR signaling pathway regulator Homo sapiens 70-73 8948466-7 1995 1H-NMR spectroscopy of 10-HCO-H2folate (in 2H2O; 300 MHz) suggested a pure compound and gave resonances for one formyl group proton, two protons on C-7 and C-9, and no evidence for a C-6 proton, which is consistent with the structure proposed. Carbon 27-28 complement C7 Gallus gallus 148-151 7498726-8 1995 Deletion of the ATP3 genomic locus resulted in an inability to utilize nonfermentable carbon sources. Carbon 86-92 F1F0 ATP synthase subunit gamma Saccharomyces cerevisiae S288C 16-20 7760058-6 1995 From the C-3/C-4 labeling ratios in glutamine and glutamate and from the corresponding C-3/C-2 labeling ratio in GABA obtained with [2-13C]acetate, it was concluded that the carbon skeleton of glutamine to some extent was passed through TCA cycles before glutamate and GABA were formed. Carbon 174-180 complement component 4B (Chido blood group) Mus musculus 13-16 7750534-0 1995 Transcriptional regulation of the yeast vacuolar aminopeptidase yscI encoding gene (APE1) by carbon sources. Carbon 93-99 metalloaminopeptidase APE1 Saccharomyces cerevisiae S288C 84-88 7750534-1 1995 Transcription of the vacuolar aminopeptidase yscI-encoding gene (APE1) is regulated by the carbon source used for yeast growth, responding to carbon catabolite repression. Carbon 91-97 metalloaminopeptidase APE1 Saccharomyces cerevisiae S288C 65-69 7739544-1 1995 The GCR1 gene product is required for maximal transcription of yeast glycolytic genes and for growth of yeast strains in media containing glucose as a carbon source. Carbon 151-157 transcription regulator GCR1 Saccharomyces cerevisiae S288C 4-8 7744070-15 1995 (Tokyo) 114, 421-431] highly thermostable chloroplast C. reinhardtii thioredoxin m that is involved in the thiol-redox enzymic control of photosynthetic intermediate carbon metabolism. Carbon 166-172 thioredoxin Homo sapiens 69-80 9488251-10 1998 Pearson"s test calculated for the C/s and the total number of packed RBC transfusions showed a positive correlation (r = .594) that was statistically significant (p < .02). Carbon 34-35 RNA, 7SL, cytoplasmic 263, pseudogene Homo sapiens 69-72 9454596-2 1998 The minimal inhibitory sequence is a tripeptide, L-tyrosinyl-L-isoleucyl-L-arginyl, which competitively inhibits the hydrolysis of small chromogenic substrates by factor Xa but binds in an orientation which prevents a productive nucleophilic attack by serine 195 of the catalytic triad on the carbonyl carbon of the carboxyterminal arginine. Carbon 293-299 coagulation factor X Homo sapiens 163-172 7698990-1 1995 By screening a collection of Saccharomyces cerevisiae mutants temperature sensitive for growth on a nonfermentable carbon source, we have isolated a gene (termed MAS37) which encodes a novel receptor for protein import into mitochondria. Carbon 115-121 SAM complex subunit SAM37 Saccharomyces cerevisiae S288C 162-167 9448707-1 1998 The enzyme squalene synthase (SS) represents the first commitment of carbon from the general isoprenoid pathway toward sterol biosynthesis and is a potential point for regulation of sterol biosynthesis. Carbon 69-75 squalene synthase Nicotiana tabacum 11-28 9448707-1 1998 The enzyme squalene synthase (SS) represents the first commitment of carbon from the general isoprenoid pathway toward sterol biosynthesis and is a potential point for regulation of sterol biosynthesis. Carbon 69-75 squalene synthase Nicotiana tabacum 30-32 7890778-2 1995 The 2-hydroxymuconic semialdehyde hydrolase, XylF, of the Pseudomonas putida TOL plasmid-encoded pathway for the catabolism of toluene and xylenes, catalyzes one of the rarest types of enzyme reaction (EC 3.7.1.9), the hydrolysis of a carbon-carbon bond in its substrate, the ring-fission product of 3-alkyl-substituted catechols. Carbon 235-241 2-hydroxymuconic semialdehyde hydrolase Pseudomonas putida 45-49 9401045-8 1997 Definition of this oruR locus and its effects upon OAcT activity provide evidence that control of ornithine levels in P. aeruginosa may have a significant impact upon how the cell is able to monitor and regulate the use of arginine and glutamate as sources of either carbon or nitrogen. Carbon 267-273 ornithine utilization transcriptional regulator OruR Pseudomonas aeruginosa PAO1 19-23 7890778-2 1995 The 2-hydroxymuconic semialdehyde hydrolase, XylF, of the Pseudomonas putida TOL plasmid-encoded pathway for the catabolism of toluene and xylenes, catalyzes one of the rarest types of enzyme reaction (EC 3.7.1.9), the hydrolysis of a carbon-carbon bond in its substrate, the ring-fission product of 3-alkyl-substituted catechols. Carbon 242-248 2-hydroxymuconic semialdehyde hydrolase Pseudomonas putida 45-49 9390015-15 1997 This indicated that C-PTH/I-PTH ratio changes were related to different circulating levels of I- and C-PTH rather than to a different composition of I- and C-PTH. Carbon 20-21 parathyroid hormone Canis lupus familiaris 22-25 9390015-15 1997 This indicated that C-PTH/I-PTH ratio changes were related to different circulating levels of I- and C-PTH rather than to a different composition of I- and C-PTH. Carbon 20-21 parathyroid hormone Canis lupus familiaris 28-31 7867719-1 1995 Cell proliferation arrest at 37 degrees C (restrictive temperature) of the cell division cycle (cdc) mutants of Saccharomyces cerevisiae cdc28, cdc35, cdc19, cdc21, and cdc17 was correlated with carbon and energy uncoupling. Carbon 195-201 cyclin-dependent serine/threonine-protein kinase CDC28 Saccharomyces cerevisiae S288C 137-142 9390015-15 1997 This indicated that C-PTH/I-PTH ratio changes were related to different circulating levels of I- and C-PTH rather than to a different composition of I- and C-PTH. Carbon 20-21 parathyroid hormone Canis lupus familiaris 28-31 9390015-15 1997 This indicated that C-PTH/I-PTH ratio changes were related to different circulating levels of I- and C-PTH rather than to a different composition of I- and C-PTH. Carbon 20-21 parathyroid hormone Canis lupus familiaris 28-31 7854322-2 1995 The expression of the PCK1 gene in Saccharomyces cerevisiae is strictly regulated and dependent on the carbon source provided. Carbon 103-109 phosphoenolpyruvate carboxykinase PCK1 Saccharomyces cerevisiae S288C 22-26 9313858-1 1997 The MAO-B catalyzed alpha-carbon oxidation of amines has been proposed to proceed via either a single electron transfer (SET) or hydrogen atom transfer (HAT) pathway. Carbon 26-32 monoamine oxidase B Homo sapiens 4-9 7857870-8 1995 The CYP450 enzymes that hydroxylate the C19 carbon of androgens (aromatase) and the C18 carbon of corticosterone (aldosterone synthase) were selected as target enzymes because they are terminal enzymes of biosynthetic pathways which hydroxylate specific angular methyl groups. Carbon 44-50 cytochrome P450 family 11 subfamily B member 2 Homo sapiens 114-134 9323366-0 1997 Constitutive and carbon source-responsive promoter elements are involved in the regulated expression of the Saccharomyces cerevisiae malate synthase gene MLS1. Carbon 17-23 malate synthase MLS1 Saccharomyces cerevisiae S288C 154-158 9323366-1 1997 The malate synthase gene, MLS1, of the yeast Saccharomyces cerevisiae is transcriptionally regulated by the carbon source in the growth medium. Carbon 108-114 malate synthase MLS1 Saccharomyces cerevisiae S288C 26-30 7857870-8 1995 The CYP450 enzymes that hydroxylate the C19 carbon of androgens (aromatase) and the C18 carbon of corticosterone (aldosterone synthase) were selected as target enzymes because they are terminal enzymes of biosynthetic pathways which hydroxylate specific angular methyl groups. Carbon 88-94 cytochrome P450 family 11 subfamily B member 2 Homo sapiens 114-134 9323366-14 1997 Thus, in order to ensure the severe glucose repression of MLS1 observed, repressor elements that respond to the carbon source must counteract constitutive activation. Carbon 112-118 malate synthase MLS1 Saccharomyces cerevisiae S288C 58-62 9323366-15 1997 In summary, ICL1 and MLS1 share common cis-acting elements, although a distinct mechanism of carbon source control also contributes to MLS1 regulation. Carbon 93-99 malate synthase MLS1 Saccharomyces cerevisiae S288C 135-139 7897322-10 1994 Acyl DHAP reductase activity in both wild type and tpa1 cells grown on a nonfermentable carbon source was increased approximately 2-fold over that of glucose-grown cells. Carbon 88-94 oxidative DNA demethylase Saccharomyces cerevisiae S288C 51-55 9044264-4 1997 The increase in SOD2 expression appears to be due to two phenomena-the switch to a non-fermentable carbon source and nutrient limitation. Carbon 99-105 superoxide dismutase SOD2 Saccharomyces cerevisiae S288C 16-20 7832976-2 1994 The compound is structurally related to the cholinesterase inhibitor heptylphysostigmine (MF 201) because the angular methyl group of the esoroline nucleus has been changed into a bridging carbon and the anilinic nitrogen has been replaced by a methylene group. Carbon 189-195 butyrylcholinesterase Homo sapiens 44-58 7929052-6 1994 Thus, homologation of carbons 26 and 27 of the vitamin D compound likely sterically hinders vitamin D 25-hydroxylase. Carbon 22-29 cytochrome P450 family 2 subfamily R member 1 Homo sapiens 92-116 8900102-1 1996 Aspergillus fumigatus can utilize chicken feather keratin as its sole carbon and nitrogen source. Carbon 70-76 keratin Gallus gallus 50-57 8900102-5 1996 Secretion of keratin-hydrolyzing activity in A. fumigatus was induced by keratin but repressed by low-molecular-weight carbon and nitrogen sources. Carbon 119-125 keratin Gallus gallus 13-20 8970157-4 1996 HXT6 is highly expressed on raffinose, low glucose, or nonfermentable carbon sources but is repressed in the presence of high concentrations of glucose. Carbon 70-76 hexose transporter HXT6 Saccharomyces cerevisiae S288C 0-4 16349347-0 1994 Bacterial Standing Stock, Activity, and Carbon Production during Formation and Growth of Sea Ice in the Weddell Sea, Antarctica. Carbon 40-46 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 89-92 8903410-9 1996 Ro31-8425, calphostin C, and genistein, which prevented HGF-induced PLD activation, inhibited induction of these immediate early genes. Carbon 22-23 hepatocyte growth factor Rattus norvegicus 56-59 7914537-9 1994 Thus, the nature of the substituent and the chirality at the carbon bridge between the naphthalene and imidazole rings play an important role in maintaining potent alpha 2-adrenoceptor activity and high alpha 2/alpha 1-selectivity within the 4-substituted imidazole class. Carbon 61-67 adrenoceptor alpha 1D Homo sapiens 211-218 8855938-1 1996 The crystal structure of the noncovalent complex of bovine thrombin and a fibrinogen-A alpha tridecapeptide substrate analog, G17 psi, in which the scissile bond amide nitrogen of Gly-17f has been replaced by a methylene carbon, has been determined at 2.3 A resolution with an R factor of 17.1%. Carbon 221-227 coagulation factor II, thrombin Bos taurus 59-67 12226414-2 1996 Hpr encodes hydroxypyruvate reductase, an enzyme important in the photorespiratory glycolate pathway, which plays an integral role in carbon allocation in C3 plants. Carbon 134-140 glycerate dehydrogenase Cucumis sativus 0-3 8185321-2 1994 In the wild type yeast, the expression of both genes is influenced by both the growth phase and the type of carbon source, indicating discrete regulatory mechanisms and metabolic roles for PYC1 and PYC2. Carbon 108-114 pyruvate carboxylase 1 Saccharomyces cerevisiae S288C 189-193 8921730-5 1996 Relative rise was closely correlated with the length of carbon chain of the SCFA, that is, n-valerate caused the largest elevation of the insulin level, followed by n-butyrate and propionate. Carbon 56-62 LOC105613195 Ovis aries 138-145 21619290-3 1996 The percolating carbon dispersion provides electrical conductivity, oxidoreductase enzymes (e.g., glucose oxidase, lactate oxidase, or l-amino acid oxidase) are used for biocatalysis, metallic palladium is used for electrocatalysis of the biochemical reaction product, and the porous organically modified silica provides a rigid skeleton. Carbon 16-22 thioredoxin reductase 1 Homo sapiens 68-82 8111016-7 1994 Acetate as a carbon source allowed accumulation of nit-1 mRNA in the dark, indicating the existence of interactions between light and carbon metabolism in nit-1 gene expression. Carbon 13-19 uncharacterized protein Chlamydomonas reinhardtii 51-56 8649384-8 1996 Disruption of yme2 causes a strain-dependent growth defect on nonfermentable carbon sources. Carbon 77-83 Yme2p Saccharomyces cerevisiae S288C 14-18 17620319-1 2007 BACKGROUND: A cohort mortality study of a large carbon black production plant in Germany showed an elevation in lung cancer mortality (SMR 1.81 (95% CI: 1.34-2.39)), although the elevation could not be linked to exposure to carbon black. Carbon 48-54 LY6/PLAUR domain containing 4 Homo sapiens 135-138 17620319-1 2007 BACKGROUND: A cohort mortality study of a large carbon black production plant in Germany showed an elevation in lung cancer mortality (SMR 1.81 (95% CI: 1.34-2.39)), although the elevation could not be linked to exposure to carbon black. Carbon 224-230 LY6/PLAUR domain containing 4 Homo sapiens 135-138 8111016-7 1994 Acetate as a carbon source allowed accumulation of nit-1 mRNA in the dark, indicating the existence of interactions between light and carbon metabolism in nit-1 gene expression. Carbon 134-140 uncharacterized protein Chlamydomonas reinhardtii 51-56 8111016-7 1994 Acetate as a carbon source allowed accumulation of nit-1 mRNA in the dark, indicating the existence of interactions between light and carbon metabolism in nit-1 gene expression. Carbon 134-140 uncharacterized protein Chlamydomonas reinhardtii 155-160 8730097-6 1996 We also show that the two genes are differentially regulated: SDC25 is not transcribed at a detectable level in growth conditions when glucose is the carbon source. Carbon 150-156 SDC25 Saccharomyces cerevisiae S288C 62-67 8262985-3 1993 The YAT1 promotor region confers the identical carbon source dependence also on the expression of beta-galactosidase when cloned 5" to the Escherichia coli lacZ-coding region. Carbon 47-53 carnitine O-acetyltransferase YAT1 Saccharomyces cerevisiae S288C 4-8 8660276-4 1996 Yeast haploids lacking PLD activity were deficient in growth on non-fermentable carbon sources. Carbon 80-86 phospholipase D Saccharomyces cerevisiae S288C 23-26 17567167-1 2007 Coherent carbon cryogel-ammonia borane (C-AB) nanocomposites were synthesized, and improved H2 storage properties are reported. Carbon 9-15 neural proliferation, differentiation and control 1 Homo sapiens 16-44 8226724-2 1993 Gal4 transcriptional activator protein binds to the two consensus UAS sites whether GAL2 expression is induced, uninduced, or repressed by growth with different carbon sources. Carbon 161-167 galactose permease GAL2 Saccharomyces cerevisiae S288C 84-88 17372271-2 2007 We previously reported that polymorphisms in methylenetetrahydrofolate reductase (MTHFR) in one-carbon pathway were associated with breast cancer risk in the population-based Long Island Breast Cancer Study Project. Carbon 96-102 methylenetetrahydrofolate reductase Homo sapiens 45-80 17372271-2 2007 We previously reported that polymorphisms in methylenetetrahydrofolate reductase (MTHFR) in one-carbon pathway were associated with breast cancer risk in the population-based Long Island Breast Cancer Study Project. Carbon 96-102 methylenetetrahydrofolate reductase Homo sapiens 82-87 17687709-3 2007 METHOD: The physiology of the one-carbon cycle, involving folate, cobalamin, homocysteine, S-adenosyl-methionine, and methylene tetrahydrofolate reductase (MTHFR) is first reviewed, and then the particular contributions of folate and B12 are reviewed. Carbon 34-40 methylenetetrahydrofolate reductase Homo sapiens 118-154 8621692-6 1996 The corresponding wild-type COQ7 gene was isolated, sequenced, and found to restore growth on nonfermentable carbon sources and the synthesis of ubiquinone. Carbon 109-115 putative monooxygenase CAT5 Saccharomyces cerevisiae S288C 28-32 8904082-4 1996 Peptide YY, an analog of neuropeptide Y, demonstrated a much lower potency for increasing the number of carbon deposits, and neuropeptide Y-(18-36), which elicits a weak antagonist action on the neuropeptide Y Y3 receptor, significantly decreased the neuropeptide Y-induced increase. Carbon 104-110 peptide YY Rattus norvegicus 0-10 17687709-3 2007 METHOD: The physiology of the one-carbon cycle, involving folate, cobalamin, homocysteine, S-adenosyl-methionine, and methylene tetrahydrofolate reductase (MTHFR) is first reviewed, and then the particular contributions of folate and B12 are reviewed. Carbon 34-40 methylenetetrahydrofolate reductase Homo sapiens 156-161 8349662-6 1993 The secondary isotope effect signals the formation of the C-O bond at C-2. Carbon 58-59 complement C2 Homo sapiens 70-73 17663266-11 2007 Studies carried out on the effect of SWCNT on superoxide dismutase (SOD-1 and SOD-2) levels in LE cells, indicates that these enzyme levels decreased by 24 hours. Carbon 37-42 superoxide dismutase 2 Rattus norvegicus 78-83 9090846-0 1996 Oxygen- and carbon source-dependent transactivation effect of ABF1 on the expression of the AAC2 gene encoding mitochondrial ADP/ATP carrier. Carbon 12-18 solute carrier family 25 member 5 Homo sapiens 92-96 8580967-10 1996 The intracellular nitrogen to carbon ratio might be an important factor for the regulation of asparagine synthetase gene expression. Carbon 30-36 LOC100856906 Zea mays 94-115 17567174-1 2007 The location of palladium nanoparticles on and inside the multiwalled carbon nanotubes channel is presented for the first time using electron tomography (3D TEM). Carbon 70-76 MFT2 Homo sapiens 157-160 8342604-6 1993 Incubation of macrophages with beta-1,3-glucan before stimulation with poly[I:C] was found to strongly attenuate the expression of Bf and beta-interferon. Carbon 78-79 hemoglobin, beta adult major chain Mus musculus 31-39 17321126-0 2007 Layer-by-layer fabrication and direct electrochemistry of glucose oxidase on single wall carbon nanotubes. Carbon 89-95 hydroxyacid oxidase 1 Homo sapiens 58-73 17321126-1 2007 Layer-by-layer assembly of glucose oxidase (GOx) with single-wall carbon nanotubes (SWCNTs) is achieved on the electrode surface based on the electrostatic attraction between positively charged GOx in pH 3.8 buffer and negatively charged carboxylic groups of CNTs. Carbon 66-72 hydroxyacid oxidase 1 Homo sapiens 27-42 17321126-1 2007 Layer-by-layer assembly of glucose oxidase (GOx) with single-wall carbon nanotubes (SWCNTs) is achieved on the electrode surface based on the electrostatic attraction between positively charged GOx in pH 3.8 buffer and negatively charged carboxylic groups of CNTs. Carbon 66-72 hydroxyacid oxidase 1 Homo sapiens 44-47 17321126-1 2007 Layer-by-layer assembly of glucose oxidase (GOx) with single-wall carbon nanotubes (SWCNTs) is achieved on the electrode surface based on the electrostatic attraction between positively charged GOx in pH 3.8 buffer and negatively charged carboxylic groups of CNTs. Carbon 66-72 hydroxyacid oxidase 1 Homo sapiens 194-197 8527437-6 1995 The syn glycosidic torsion angle at [AF]dG6 is supported by both carbon and proton chemical shift data for the sugar resonances of the modified deoxyguanosine residue. Carbon 65-71 synemin Homo sapiens 4-7 8528003-6 1995 Cdc28 and cdc35 mutants of Saccharomyces cerevisiae had been previously shown to exhibit high respiratory quotients (from 3 to 7) in respect to the WT (RQ approximately 1.0), which correlated with carbon and energy uncoupling probably the result of glucose-induced catabolite repression [Aon MA, Monaco ME, Cortassa S (1995) Exp Cell Res 217, 42-51; Monaco ME, Valdecantos PA, Aon MA (1995) Exp Cell Res 217, 52-56]. Carbon 197-203 adenylate cyclase Saccharomyces cerevisiae S288C 10-15 7592663-1 1995 The berberine bridge enzyme ((S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming), EC 1.5.3.9) catalyzes the oxidative cyclization of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon, C-8, of (S)-scoulerine. Carbon 209-215 thioredoxin reductase 1 Homo sapiens 51-65 8393112-1 1993 A series of 6-fluoro-1,4-dihydro-4-oxo-3-quinoline- and 1,8-naphthyridinecarboxylic acids, substituted at the 7-position with carbon-linked side chains, was synthesized and evaluated for antibacterial activity and DNA-gyrase inhibition. Carbon 126-132 DNA topoisomerase II alpha Homo sapiens 214-224 7584821-7 1995 Production of succinic acid by SSADH allows entry of the GABA carbon skeleton into the tricarboxylic acid cycle. Carbon 62-68 aldehyde dehydrogenase 5 family member A1 Homo sapiens 31-36 7916673-4 1993 Loss of MGM1 resulted in slow growth on rich medium, failure to grow on non-fermentable carbon sources, and loss of mitochondrial DNA. Carbon 88-94 dynamin-related GTPase MGM1 Saccharomyces cerevisiae S288C 8-12 7588747-2 1995 Transcription of the QCR8 gene, encoding subunit VIII of the Saccharomyces cerevisiae mitochondrial ubiquinol-cytochrome c oxidoreductase (QCR), is controlled by the carbon-source-dependent heme-activator protein complex HAP2/3/4 and the general transcriptional regulators autonomous replication-site-binding factor ABF1 and centromere-binding and promoter-binding factor CPF1. Carbon 166-172 Cbf1p Saccharomyces cerevisiae S288C 372-376 17368016-1 2007 For the first time glucose oxidase (GOx) was successfully co-deposited on nickel-oxide (NiO) nanoparticles at a glassy carbon electrode. Carbon 119-125 hydroxyacid oxidase 1 Homo sapiens 19-34 17368016-1 2007 For the first time glucose oxidase (GOx) was successfully co-deposited on nickel-oxide (NiO) nanoparticles at a glassy carbon electrode. Carbon 119-125 hydroxyacid oxidase 1 Homo sapiens 36-39 17368016-5 2007 The surface coverage and heterogeneous electron transfer rate constant (k(s)) of GOx immobilized on NiO film glassy carbon electrode are 9.45 x 10(-13)mol cm(-2) and 25.2+/-0.5s(-1), indicating the high enzyme loading ability of the NiO nanoparticles and great facilitation of the electron transfer between GOx and NiO nanoparticles. Carbon 116-122 hydroxyacid oxidase 1 Homo sapiens 81-84 8391533-12 1993 These results suggest that the role of protein UspA may be to modulate and reorganize the flow of carbon in the central metabolic pathways of E. coli during growth arrest. Carbon 98-104 putative universal stress protein UspA Escherichia coli 47-51 17074433-7 2007 Results show a good performance of activated carbon in this reaction that is in relationship with BET surface area. Carbon 45-51 bet Drosophila melanogaster 98-101 17436239-3 2007 We studied the MTHFR 677C-->T polymorphism and B vitamins as modulators of one-carbon metabolism in 10,601 adults from the Norwegian Colorectal Cancer Prevention (NORCCAP) cohort, using plasma total homocysteine (tHcy) as the main outcome measure. Carbon 82-88 methylenetetrahydrofolate reductase Homo sapiens 15-20 17436239-8 2007 The study provides comprehensive data on the MTHFR-B vitamin network, which has major effects on the transfer of one-carbon units. Carbon 117-123 methylenetetrahydrofolate reductase Homo sapiens 45-50 7649170-6 1995 The 13C-enrichment ratio between glutamine carbons C2 and C3 was close to 1 in the presence of exogenous glutamine whereas it was higher than 1 in its absence, indicating that pyruvate carboxylase was more active in the absence of glutamine. Carbon 43-50 pyruvate carboxylase Rattus norvegicus 176-196 7622489-5 1995 We conclude that CYP24 must be directed to its hydroxylation site(s) by the distance of carbon 24 from the vitamin D ring structure and not as in CYP27 by the distance of the hydroxylation site from the end of the side chain. Carbon 88-94 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 17-22 7775433-8 1995 Our results show that the removal of double bonds from odd-numbered carbons in arachidonic acid thus requires both NADPH-dependent 2,4-dienoyl-CoA reductase and delta 3,5,delta 2,4-dienoyl-CoA isomerase. Carbon 68-75 2,4-dienoyl-CoA reductase 1 Homo sapiens 115-120 8232264-4 1993 Common structural features, i.e. the presence of carboxylic groups and of hydrophobic carbon chains led to the hypothesis that both ligands interact similarly with L-FABP. Carbon 86-92 fatty acid binding protein 1 Bos taurus 164-170 7647551-3 1995 It was observed that, for the instances with syn bases, the C1" through C4" carbons showed shifts that may be distinguished from those normally found in B-DNA-like structures. Carbon 76-83 synemin Homo sapiens 45-48 7749279-0 1995 Comparison of trihalomethane in tap water with and without activated carbon adsorption during the preparation process of tap water. Carbon 69-75 nuclear RNA export factor 1 Homo sapiens 121-124 17688797-3 2007 (CEAP clinical scale: C(4) 31, C(5) 1, C(6) 2). Carbon 22-23 biogenesis of lysosomal organelles complex 1 subunit 2 Homo sapiens 1-5 17688797-3 2007 (CEAP clinical scale: C(4) 31, C(5) 1, C(6) 2). Carbon 22-23 biogenesis of lysosomal organelles complex 1 subunit 2 Homo sapiens 1-5 17739800-5 1993 The results indicate that carbon grows first in linear chains, transforms to monocyclic planar rings at about C(10), and forms new families of planar bi-, tri-, and tetracyclic rings at C(20), C(30), and C(40), respectively. Carbon 26-32 CCR4-NOT transcription complex subunit 11 Homo sapiens 204-209 17298095-4 2007 The proposed protocol is based on a newly assembled 13C GARP broadband decoupled proton acquisition sequence that reduces spectroscopic complexity by removal of carbon satellites. Carbon 161-167 leucine rich repeat containing 32 Homo sapiens 56-60 17410791-11 2007 PM1.8 and PM0.1 source profiles constructed using the relative abundance of hopanes and steranes to total organic carbon were functions of vehicle load condition. Carbon 114-120 transmembrane protein 11 Homo sapiens 0-3 17441171-2 2007 Nucleophilic addition of RMgBr or RLi proceeded regioselectively at the distal carbon atom of the allenylidene array. Carbon 79-85 ATP binding cassette subfamily E member 1 Homo sapiens 34-37 7962057-5 1994 When Fas is active and NMT1 cells are grown on media containing a fermentable carbon source, none of the FAA genes is required for vegetative growth. Carbon 78-84 glycylpeptide N-tetradecanoyltransferase NMT1 Saccharomyces cerevisiae S288C 23-27 7962057-15 1994 A NMT1 strain with deletions of all four FAAs is still viable at 30 degrees C on media containing myristate, palmitate, or oleate as the sole carbon source--indicating that S. cerevisiae contains at least one other FAA which directs fatty acids to beta-oxidation pathways. Carbon 142-148 glycylpeptide N-tetradecanoyltransferase NMT1 Saccharomyces cerevisiae S288C 2-6 11536532-3 1993 reported that anoxygenic photosynthesis may be an important component of carbon cycling in the present Black Sea, owing to a shoaling of the chemocline and consequent penetration of the photic zone by anaerobic waters in the past few decades. Carbon 73-79 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 109-112 7817767-4 1994 The reaction of 2 with cis-2-hydroxymethylcyclohexylamine gave the tetracyclic (8), while 2 and diendo-3-hydroxymethylbicyclo[2.2.1]hept-5-enyl-2-amine yielded the isomers (9a,b), which differ in the mutual positions of the phenyl group on the quaternary carbon and cyclohexane annelation hydrogens. Carbon 255-261 suppressor of cytokine signaling 2 Homo sapiens 23-28 8097110-2 1993 This supports a deprotonation/protonation mechanism for racemization in which the breaking of the carbon-hydrogen bond at C-2 is partially rate-determining. Carbon 98-104 complement C2 Homo sapiens 122-125 7849073-1 1994 The bimolecular rate constants for the reactions of five organic two-electron redox mediators with reduced glucose oxidase (GOx) were determined by measuring voltammetric electrocatalytic currents at glassy carbon electrodes in the presence of excess glucose under anaerobic conditions. Carbon 207-213 hydroxyacid oxidase 1 Homo sapiens 107-122 7849073-1 1994 The bimolecular rate constants for the reactions of five organic two-electron redox mediators with reduced glucose oxidase (GOx) were determined by measuring voltammetric electrocatalytic currents at glassy carbon electrodes in the presence of excess glucose under anaerobic conditions. Carbon 207-213 hydroxyacid oxidase 1 Homo sapiens 124-127 8092987-4 1994 Structure-binding relation experiments revealed a high affinity of E-FABP for stearic acid which decreased on reduction of the number of carbon atoms or introduction of double bonds into the fatty acid chain. Carbon 137-143 fatty acid binding protein 5 Homo sapiens 67-73 17453684-5 2007 The patient with the AZFb + c deletion lacked expression of DAZ and RBMY1 and had a histopathology of SCO. Carbon 28-29 deleted in azoospermia 1 Homo sapiens 60-63 8099891-3 1993 Our results point to an involvement in the life cycle of the PHO2 activator and the PHO85-negative factor and to a reduced ability of the negative pho regulatory mutants, pho80 and pho85, to grow on non-fermentable carbon sources. Carbon 215-221 Pho2p Saccharomyces cerevisiae S288C 61-65 17434423-0 2007 Neurite outgrowths of neurons with neurotrophin-coated carbon nanotubes. Carbon 55-61 brain derived neurotrophic factor Homo sapiens 35-47 7680855-8 1993 competition binding studies show that the binding affinity of acyl-CoA esters for rACBP is strongly dependent on the length of the acyl chain with a clear preference for acyl-CoA esters with 14-22 carbon atoms in the acyl chain. Carbon 197-203 diazepam binding inhibitor Rattus norvegicus 82-87 17270400-1 2007 In the cerebral prefrontal cortex (PFC), DNA-methyltransferase 1 (DNMT1), the enzyme that catalyzes the methylation of cytosine at carbon atoms in position 5 in CpG dinucleotides, is expressed selectively in GABAergic neurons and is upregulated in layers I and II of schizophrenia (SZ) and bipolar disorder patients with psychosis (BDP). Carbon 131-137 DNA methyltransferase 1 Homo sapiens 66-71 17253797-5 2007 These data strongly support an intramolecular (Ei) syn path for elimination of acetic acid, most likely through the oxyanion produced by nucleophilic attack at the carbonyl carbon of the beta-acetoxy group. Carbon 164-170 synemin Homo sapiens 51-54 12232308-7 1994 The induction of CA activity, protein abundance, and transcript levels by exposure to limiting inorganic carbon (Ci) concentrations is much more pronounced at higher than at lower pH values. Carbon 105-111 uncharacterized protein Chlamydomonas reinhardtii 17-19 7841313-0 1994 Potential-mediated and time-controlled first order activation of factor XII (Hageman factor) adsorbed to carbon surfaces. Carbon 105-111 coagulation factor XII Homo sapiens 77-91 8458009-6 1993 The 13C-labeling at C-6 and C-2 in the starting glucoses is well preserved in the C-6 carbon and the C-1 to C-3 carbons, respectively, in the curdlan produced. Carbon 86-92 complement C2 Homo sapiens 28-31 12232269-9 1994 Determination of photosynthetic metabolite pool sizes from leaves at different positions within a soybean canopy showed a limitation to carbon uptake at the stromal FBPase and possibly the sedoheptulose-1,7-bisphosphatase (EC 3.1.3.37) in shade leaves upon initial illumination at saturating PFD levels. Carbon 136-142 fructose-1,6-bisphosphatase, chloroplastic Glycine max 165-171 8264590-7 1994 DRS1, a pair of adjacent and opposing ABF1 sites (+288 to +313), is responsible for a 1.3- to 2-fold repression of transcription, depending on the carbon source. Carbon 147-153 putative ATP-dependent RNA helicase Saccharomyces cerevisiae S288C 0-4 17251975-0 2007 Transformation of spin information into large electrical signals using carbon nanotubes. Carbon 71-77 spindlin 1 Homo sapiens 18-22 8458009-6 1993 The 13C-labeling at C-6 and C-2 in the starting glucoses is well preserved in the C-6 carbon and the C-1 to C-3 carbons, respectively, in the curdlan produced. Carbon 112-119 complement C2 Homo sapiens 28-31 17251975-6 2007 This spintronic system combines a number of favourable properties that enable this performance; the long spin lifetime in nanotubes due to the small spin-orbit coupling of carbon; the high Fermi velocity in nanotubes that limits the carrier dwell time; the high spin polarization in the manganite electrodes, which remains high right up to the manganite-nanotube interface; and the resistance of the interfacial barrier for spin injection. Carbon 172-178 spindlin 1 Homo sapiens 5-9 8458009-6 1993 The 13C-labeling at C-6 and C-2 in the starting glucoses is well preserved in the C-6 carbon and the C-1 to C-3 carbons, respectively, in the curdlan produced. Carbon 112-119 heterogeneous nuclear ribonucleoprotein C Homo sapiens 101-111 8454567-5 1993 The upfield shift of 2-13C of MCAD relative to that of FMN in the aqueous medium and its downfield shift relative to that of tetraacetylriboflavin in an apolar medium imply that a weaker hydrogen bond exists between C(2) = O and apoMCAD or a water molecule than that of free FMN with a water molecule. Carbon 25-26 formin 1 Homo sapiens 275-278 19071278-1 2007 A poly(vinyl alcohol) film cross-linked with glutaraldehyde (PVA-GA) was introduced to the surface of a tyrosinase-based carbon paste electrode. Carbon 121-127 tyrosinase Homo sapiens 104-114 17233730-8 2007 Increased protease activity and BPP allow attached bacteria to quickly exploit aggregate resources upon attachment, which may accelerate remineralization of marine snow and reduce the downward carbon fluxes. Carbon 193-199 sushi repeat containing protein X-linked 2 Homo sapiens 32-35 8395517-8 1993 Null mutants of COX13, generated by gene replacement, showed a slightly reduced growth rate on nonfermentable carbon sources. Carbon 110-116 cytochrome c oxidase subunit VIa Saccharomyces cerevisiae S288C 16-21 8347671-6 1993 (3) In fluid-phase PC membranes possessing short alkyl chains (12-14 carbons), the activation energy of the rotational diffusion of 16-doxylstearic acid spin label (16-SASL) is significantly lower at a carotenoid concentration of 10 mol%. Carbon 69-76 spindlin 1 Homo sapiens 153-157 17913161-2 2007 Total organic carbon (TOC) and chemical oxygen demand (COD(Cr)) assays show that the degradation rate of SRB is much higher when irradiated with UV and sunlight compared with visible light. Carbon 14-20 chaperonin containing TCP1 subunit 4 Homo sapiens 105-108 8454567-6 1993 That the 4-13C resonance was observed downfield-shifted relative to that of free FMN in aqueous solution suggests a strong hydrogen bond between C(4) = O and apoMCAD. Carbon 13-14 formin 1 Homo sapiens 81-84 8328951-1 1993 Growth of Pseudomonas AT3 on the alkaloid atropine as its sole source of carbon and nitrogen is nitrogen-limited and proceeds by degradation of the tropic acid part of the molecule, with the metabolism of the tropine being limited to the point of release of its nitrogen. Carbon 73-79 ataxin 3 Homo sapiens 22-25 11539430-7 1993 In the context of terraforming Mars, selected microorganisms isolated from absolute extreme environments are considered for use in creation of a biological carbon cycle. Carbon 156-162 methionyl-tRNA synthetase 1 Homo sapiens 31-35 9908824-0 1992 Fusion yields for carbon-cluster impact on CD2 targets. Carbon 18-24 CD2 molecule Homo sapiens 43-46 8369438-3 1993 The epsilon-Lys-216 chemical shifts in bR555 (48 ppm) and bR568 (53 ppm) are consistent with a C = N isomerization from syn in bR555 to anti in bR568. Carbon 95-96 synemin Homo sapiens 120-123 17892040-3 2007 Most important EFA is gamma-linolenic acid (GLA)--18 carbons, one-carboxylic, non-branched fatty acid with 3 double cis-bonds (the last is situated by 6-th carbon from methylic end). Carbon 53-60 galactosidase alpha Homo sapiens 44-47 17892040-3 2007 Most important EFA is gamma-linolenic acid (GLA)--18 carbons, one-carboxylic, non-branched fatty acid with 3 double cis-bonds (the last is situated by 6-th carbon from methylic end). Carbon 53-59 galactosidase alpha Homo sapiens 44-47 1518834-5 1992 The sn-2 chain bends around the C-2 carbon to lie next to the sn-1 chain. Carbon 36-42 complement C2 Homo sapiens 32-35 17132008-3 2006 A deuterium-labeling experiment indicates that the oxidative addition proceeds via SN2-type attack of palladium(0) on the less-hindered carbon of the aziridine ring and that alkene insertion occurs in a syn fashion. Carbon 136-142 synemin Homo sapiens 203-206 8358820-9 1993 In most cases, a distinct though small influence of the carbon source on the expression of an MRP-L6/lacZ reported construct was observed. Carbon 56-62 mitochondrial 54S ribosomal protein YmL16 Saccharomyces cerevisiae S288C 94-100 8099357-10 1993 A double mutant lacking both IDP1 and IDH activities proved to be auxotrophic for glutamate during growth on glucose, but was capable of growth independent of added glutamate on non-fermentable carbon sources. Carbon 194-200 isocitrate dehydrogenase (NADP(+)) IDP1 Saccharomyces cerevisiae S288C 29-33 17164363-1 2006 The Ala(222)Val single nucleotide polymorphism (SNP) in the gene for 5,10-methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in one-carbon metabolism, has been associated with colorectal cancer risk. Carbon 144-150 methylenetetrahydrofolate reductase Homo sapiens 69-109 1324716-1 1992 Bovine rhodopsin has been reconstituted in seven different saturated diacylphosphatidylcholine species of odd and even chain lengths from C-12 to C-18 at a lipid/protein ratio (60:1 mol/mol) comparable to that in the native rod outer segment disk membrane. Carbon 138-139 rhodopsin Bos taurus 7-16 17164363-1 2006 The Ala(222)Val single nucleotide polymorphism (SNP) in the gene for 5,10-methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in one-carbon metabolism, has been associated with colorectal cancer risk. Carbon 144-150 methylenetetrahydrofolate reductase Homo sapiens 111-116 17164363-9 2006 Our results corroborate previous findings for MTHFR Ala(222)Val and suggest that other genes involved in one-carbon metabolism, particularly those that affect DNA methylation, may be associated with colorectal cancer risk. Carbon 109-115 methylenetetrahydrofolate reductase Homo sapiens 46-51 8489244-1 1993 Cleavage of heme b (Fe-protoporphyrin IX) at the alpha-meso carbon bridge is catalyzed by heme oxygenase isozymes, HO-1 and HO-2, to form biliverdin IX alpha. Carbon 60-66 heme oxygenase 1 Rattus norvegicus 115-128 1324716-1 1992 Bovine rhodopsin has been reconstituted in seven different saturated diacylphosphatidylcholine species of odd and even chain lengths from C-12 to C-18 at a lipid/protein ratio (60:1 mol/mol) comparable to that in the native rod outer segment disk membrane. Carbon 146-147 rhodopsin Bos taurus 7-16 8471631-4 1993 Pure benzalkonium chloride, with a fourteen-carbon-atom aliphatic chain (BAC (C14)), at 5 to 10 microM also inhibited histamine release induced by GTP gamma S and mastoparan. Carbon 44-50 anti-Mullerian hormone receptor type 2 Rattus norvegicus 78-81 17115712-7 2006 In contrast, the FXa-catalyzed hydrolysis of N-alpha-Z-D-Arg-Gly-Arg-pNA.2HCl (S-2765) and H-D-Ile-L-Pro-L-Arg-pNA.HCl (S-2288) is most consistent with two-proton bridges forming at the transition state between Ser195 OgammaH and His57 N(epsilon)2 and His57 Ndelta1 and Asp102 COObeta- at the active site, with transition-state fractionation factors of phi1 = phi2 = 0.57 +/- 0.07 and phiS = 0.78 +/- 0.16 for solvent rearrangement for S-2765 and phi1 = phi2 = 0.674 +/- 0.001 for S-2288 under enzyme saturation with the substrate at pH 8.40 and 25.0 +/- 0.1 degrees C. The rate-determining step(s) in these reactions is most likely the cleavage of the C-N bond and departure of the leaving group. Carbon 75-76 coagulation factor X Homo sapiens 17-20 1321617-4 1992 The results lead to the conclusion that the hydroxyl radical formed in Fe(II)-elsamicin A plus dithiothreitol system oxidizes the deoxyribose moiety via hydrogen abstraction predominantly at the C-4" carbon of the deoxyribose backbone and ultimately produces strand breakage of DNA. Carbon 200-206 complement C4A (Rodgers blood group) Homo sapiens 195-198 17090056-4 2006 The primary intrinsic KIEs (1"-(14)C and 9-(15)N) suggest that MTAP has a dissociative S(N)1 transition state with its cationic center at the anomeric carbon and insignificant bond order to the leaving group. Carbon 151-157 methylthioadenosine phosphorylase Homo sapiens 63-67 8441997-3 1993 Oxidation at the terminal (C-3) carbon atom of the propyl groups of Tris-BP yielded the direct-acting mutagen 2-bromoacrolein as the major metabolite that binds to DNA. Carbon 32-38 complement C3 Rattus norvegicus 27-30 1314953-9 1992 Domain 1 is essential for transcription per se in cells grown on repressing carbon sources, is required for optimal transcription in cells grown on a derepressing carbon source, is sufficient for glucose repression-derepression, and is the element of UAS6 at which HAP2 affects COX6 transcription. Carbon 76-82 transcription activator HAP2 Saccharomyces cerevisiae S288C 265-269 1314953-9 1992 Domain 1 is essential for transcription per se in cells grown on repressing carbon sources, is required for optimal transcription in cells grown on a derepressing carbon source, is sufficient for glucose repression-derepression, and is the element of UAS6 at which HAP2 affects COX6 transcription. Carbon 163-169 transcription activator HAP2 Saccharomyces cerevisiae S288C 265-269 1447566-2 1992 The temperature dependence of such rates showed that some carbons were experiencing slow exchange regimes such that kinetic parameters at room temperature could be calculated (k(off) = 1400 sec-1, delta H* = 12.0 kcal/mol, delta S* = -9.9 e.u.). Carbon 58-65 secretory blood group 1, pseudogene Homo sapiens 190-195 16966319-3 2006 Here we show that GPR84, a previously orphan G protein-coupled receptor, functions as a receptor for medium-chain FFAs with carbon chain lengths of 9-14. Carbon 124-130 G protein-coupled receptor 84 Homo sapiens 18-23 1314953-14 1992 Together, these findings permit the following conclusions: COX6 transcription is regulated both positively and negatively; heme and carbon source exert their effects through different sites; domain 1 is absolutely essential for transcription on repressing carbon sources; ABF1 is a major component in the regulation of COX6 transcription; and the HAP2/3/4 complex most likely affects COX6 transcription indirectly. Carbon 256-262 cytochrome c oxidase subunit VI Saccharomyces cerevisiae S288C 59-63 1454530-3 1992 Expression of MLS1, which participates in the utilization of non-fermentable carbon sources, is sensitive to carbon catabolite repression, but nearly insensitive to nitrogen catabolite repression. Carbon 77-83 malate synthase MLS1 Saccharomyces cerevisiae S288C 14-18 1304366-9 1992 The distance between the alpha-carbons of these residues in the crystal structure is 15.5 A, whereas only 12.0 A can be spanned by the two side chains linked by a dioxobutyl group, suggesting either that pyruvate kinase undergoes a conformational change in forming the cross-link or that local rapid fluctuations in structure occur in solution to the extent of 3.5 A in this region of pyruvate kinase. Carbon 31-38 pyruvate kinase PKLR Oryctolagus cuniculus 204-219 1467941-2 1992 Pressure-ejection of 50 microM CCK-8S into the CPu induced voltammetric signals recorded at widely spaced Nafion-coated carbon fiber microelectrodes. Carbon 120-126 cholecystokinin Rattus norvegicus 31-34 16777985-1 2006 Methylenetetrahydrofolate reductase (MTHFR) balances the pool of folate coenzymes in one-carbon metabolism for DNA synthesis and methylation, both are implicated in carcinogenesis. Carbon 89-95 methylenetetrahydrofolate reductase Homo sapiens 0-35 16777985-1 2006 Methylenetetrahydrofolate reductase (MTHFR) balances the pool of folate coenzymes in one-carbon metabolism for DNA synthesis and methylation, both are implicated in carcinogenesis. Carbon 89-95 methylenetetrahydrofolate reductase Homo sapiens 37-42 1532227-1 1992 Serine hydroxymethyltransferase (SHMT) occupies a central position in one-carbon (C1) metabolism, catalyzing the reaction of serine and tetrahydrofolate to yield glycine and 5,10-methylenetetrahydrofolate. Carbon 74-80 serine hydroxymethyltransferase 1 Homo sapiens 33-37 17017789-3 2006 These fragments were linked by a challenging conjugate addition reaction that also generated the C11 quaternary carbon stereocenter. Carbon 112-118 RNA polymerase III subunit K Homo sapiens 97-100 17020311-2 2006 The approach involves a formal two-carbon ring expansion of heterocyclic cyclopentanones through a base-induced anionic domino three-component transformation named the MARDi cascade leading either to oxa-, aza-, or thiacycloheptanes bearing up to five contiguous stereogenic centers. Carbon 35-41 small integral membrane protein 24 Homo sapiens 168-173 1618766-4 1992 On the basis of these results, replacement of Leu29(B10) by Ala or Ile appears to allow bound CO to rotate from a conformation pointing toward the beta meso carbon of the heme group to the one pointing toward the alpha meso carbon atom, presumably filling the space left by removal of the delta 2 carbon atom of Leu29(B10). Carbon 157-163 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 46-55 1618766-4 1992 On the basis of these results, replacement of Leu29(B10) by Ala or Ile appears to allow bound CO to rotate from a conformation pointing toward the beta meso carbon of the heme group to the one pointing toward the alpha meso carbon atom, presumably filling the space left by removal of the delta 2 carbon atom of Leu29(B10). Carbon 157-163 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 52-55 1536570-1 1992 Exposure of MCF-7 breast cancer cells to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes an elevated cytochrome P450 content and a marked increase in the microsomal hydroxylation of 17 beta-estradiol (E2) at the C-2, C-4, C-15 alpha, and C-6 alpha positions. Carbon 13-14 complement C2 Homo sapiens 214-217 1371117-2 1992 One mechanism proposed for catalysis of the PPIase reaction requires attack of an enzyme nucleophile on the carbonyl carbon of the isomerized peptide bond. Carbon 108-114 FKBP prolyl isomerase 10 Homo sapiens 44-50 16782343-3 2006 13C-31P RDX (Rotational-Echo Double Resonance for X-clusters) experiments clearly revealed the REDOR dephasing effects for carbon atoms residing in the both terminal parts, whereas no dephasing was observed for the middle parts including polyolefinic C20-C33 and hydroxyl-bearing C8/C9 parts. Carbon 123-129 radixin Homo sapiens 8-11 1536570-1 1992 Exposure of MCF-7 breast cancer cells to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes an elevated cytochrome P450 content and a marked increase in the microsomal hydroxylation of 17 beta-estradiol (E2) at the C-2, C-4, C-15 alpha, and C-6 alpha positions. Carbon 13-14 complement C4A (Rodgers blood group) Homo sapiens 219-222 16963786-2 2006 Carbonyl carbons of GroEL were labeled with (13)C in an amino acid specific manner in order to reduce the number of signals to be observed in the spectrum. Carbon 9-16 heat shock protein family D (Hsp60) member 1 Homo sapiens 20-25 1349449-9 1992 A new gene (GPR1 = glyoxylate pathway regulation) was detected in which trans-dominant mutations inhibit expression of ACS and the glyoxylate cycle on acetate as carbon source. Carbon 162-168 Gpr1p Saccharomyces cerevisiae S288C 12-16 16956297-3 2006 Bisphosphonates, pyrophosphate analogues in which the oxygen bridge between the two phosphorus atoms has been replaced by a carbon substituted with different side chains, are able to inhibit the FPPS enzyme. Carbon 124-130 farnesyl diphosphate synthase Homo sapiens 195-199 1284844-3 1992 Production of L-asparaginase from S. aureus NCTC 4135 was inhibited by all carbon sources, mono- and disaccharides added to the growth medium. Carbon 75-81 AT695_RS10140 Staphylococcus aureus 14-28 1924354-4 1991 Gel-permeation chromatography of [3H]mevalonate-labeled hydrocarbons released from immunoprecipitated ras proteins overexpressed in COS cells indicated that Ha-ras p21(Leu-189) was also a substrate for 20-carbon isoprenyl modification in vivo. Carbon 61-67 H3 histone pseudogene 16 Homo sapiens 164-167 16857389-8 2006 The inhibition of P-gp was observed as a rapid increase in brain concentrations of [(11)C]verapamil, with a maximum after 5, 7.5 and 17.5 min for the respective doses. Carbon 87-89 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 18-22 16925420-4 2006 If the 7-hydroxy products are captured by triflic anhydride, then the resulting aryl triflate can be used to access 3H-naphtho[2.1-b]pyrans bearing C-7 carbon substituents. Carbon 152-158 complement C7 Homo sapiens 148-151 1652057-1 1991 We found that cells of Saccharomyces cerevisiae have an elevated level of the NAD-dependent glutamate dehydrogenase (NAD-GDH; encoded by the GDH2 gene) when grown with a nonfermentable carbon source or with limiting amounts of glucose, even in the presence of the repressing nitrogen source glutamine. Carbon 185-191 glutamate dehydrogenase (NAD(+)) Saccharomyces cerevisiae S288C 141-145 16916021-8 2006 A significant correlation between PCe and PCB removal from solution was observed for the fly ashes and activated carbon, whereas the nonplanar sorbent octadecyl (C18) indicated no relationship. Carbon 113-119 Pyruvate carboxylase Drosophila melanogaster 42-45 1652057-3 1991 This UAS was found to be separable from a neighboring element which is necessary for the nitrogen source regulation of the gene, and strains deficient for the GLN3 gene product, required for expression of NAD-GDH during growth with the activating nitrogen source glutamate, were unaffected for the expression of NAD-GDH during growth with activating carbon sources. Carbon 350-356 nitrogen-responsive transcriptional regulator GLN3 Saccharomyces cerevisiae S288C 159-163 16836436-4 2006 The C-Cl and C-S bond fissions that start from the S2 state are the dominant channels upon photodecomposition of ClC(O)SCl in the gas and condensed phases in the wavelength range of 200-248 nm. Carbon 4-5 Charcot-Leyden crystal galectin Homo sapiens 113-116 1652057-5 1991 Carbon regulation of GDH2 was found to be normal in hxk2, hap3, and hap4 strains and to be only slightly altered in a ssn6 strain; thus, in comparison with the regulation of previously identified glucose-repressed genes, a new pathway appears to be involved in the regulation of GDH2. Carbon 0-6 glutamate dehydrogenase (NAD(+)) Saccharomyces cerevisiae S288C 21-25 1652057-5 1991 Carbon regulation of GDH2 was found to be normal in hxk2, hap3, and hap4 strains and to be only slightly altered in a ssn6 strain; thus, in comparison with the regulation of previously identified glucose-repressed genes, a new pathway appears to be involved in the regulation of GDH2. Carbon 0-6 hexokinase 2 Saccharomyces cerevisiae S288C 52-56 1652057-5 1991 Carbon regulation of GDH2 was found to be normal in hxk2, hap3, and hap4 strains and to be only slightly altered in a ssn6 strain; thus, in comparison with the regulation of previously identified glucose-repressed genes, a new pathway appears to be involved in the regulation of GDH2. Carbon 0-6 Hap3p Saccharomyces cerevisiae S288C 58-62 1652057-5 1991 Carbon regulation of GDH2 was found to be normal in hxk2, hap3, and hap4 strains and to be only slightly altered in a ssn6 strain; thus, in comparison with the regulation of previously identified glucose-repressed genes, a new pathway appears to be involved in the regulation of GDH2. Carbon 0-6 glutamate dehydrogenase (NAD(+)) Saccharomyces cerevisiae S288C 279-283 1822995-8 1991 Because wheat and maize rbcS promoters show sequence homologies and similar expression patterns in monocot and dicot leaf cells, it appears likely that monocots share conserved regulatory elements irrespective of whether they utilize the C3 or C4 pathway for carbon fixation. Carbon 259-265 ribulose bisphosphate carboxylase small subunit, chloroplastic Zea mays 24-28 16816472-7 2006 In addition to the C-24 oxidation pathway, human CYP24A1 catalyzed also C-23 oxidation pathway to produce 1alpha, 25 (OH) (2)D(3)-26, 23-lactone. Carbon 19-20 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 49-56 2050045-8 1991 Liver microsomes were more active than lung microsomes in the alpha-carbon hydroxylation of NNK, suggesting that some liver isozymes of cytochrome P-450 have a high affinity for NNK. Carbon 68-74 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 136-152 16732675-2 2006 In this context, emphasis is placed on amperometric biosensors based on LOx that have been immobilized by direct absorption on carbon surfaces, in particular, glassy carbon (GC) and highly ordered pyrolytic graphite (HOPG). Carbon 127-133 lysyl oxidase Homo sapiens 72-75 1987150-5 1991 Studies with transcriptional fusions between ugp and a promoterless gene for chloramphenicol acetyltransferase show that the upstream promoter is induced by carbon starvation in a manner that required the cya and crp genes. Carbon 157-163 chloramphenicol acetyltransferase Escherichia coli 77-110 16732675-2 2006 In this context, emphasis is placed on amperometric biosensors based on LOx that have been immobilized by direct absorption on carbon surfaces, in particular, glassy carbon (GC) and highly ordered pyrolytic graphite (HOPG). Carbon 166-172 lysyl oxidase Homo sapiens 72-75 1986231-1 1991 The major nonmitochondrial isozyme of malate dehydrogenase (MDH2) in Saccharomyces cerevisiae cells grown with acetate as a carbon source was purified and shown by sodium dodecyl sulfate-polyacrylamide gel electrophoresis to have a subunit molecular weight of approximately 42,000. Carbon 124-130 malate dehydrogenase MDH2 Saccharomyces cerevisiae S288C 60-64 2127555-6 1990 S. cerevisiae cells transformed with a plasmid, pRD1, containing both the xylose reductase gene (XYL1) and the xylitol dehydrogenase gene (XYL2), were able to grow on xylose as a sole carbon source. Carbon 184-190 D-xylulose reductase XYL2 Saccharomyces cerevisiae S288C 139-143 16481173-4 2006 Compounds 9d (anthroyloxy) and 10d (nitrobenzoxadiazole), having a C9-carbon chain between the chromanol and the fluorophore, were shown to bind specifically and reversibly to recombinant human tocopherol transfer protein (alpha-TTP) with dissociation constants of approximately 280 and 60 nM, respectively, as compared to 25 nM for the natural ligand 2R,4"R,8"R-alpha-tocopherol. Carbon 70-76 alpha tocopherol transfer protein Homo sapiens 223-232 16774310-0 2006 Spin-dependent transport through a magnetic carbon nanotube-molecule junction. Carbon 44-50 spindlin 1 Homo sapiens 0-4 16491495-1 2006 A new series of hydrocarbon cages containing hexa- and octacoordinate carbon centers were designed theoretically by performing DFT calculations at the B3 LYP/6-311+G** level. Carbon 21-27 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 154-157 2176080-8 1990 Our results suggest that the increases in HMG-CoA reductase and the LDL receptor are initiated by the decreased flux of carbon units in the cholesterol-synthetic pathway, owing to inhibition of ATP citratelyase. Carbon 120-126 low density lipoprotein receptor Homo sapiens 68-80 16470384-8 2006 Additional strain-specific phenotypes associated with deletion of YNM3 included inability to grow on non-fermentable carbon sources and altered cellular morphology. Carbon 117-123 Nma111p Saccharomyces cerevisiae S288C 66-70 2170531-5 1990 Pretreatment of neutrophils with either GM-CSF or TNF-alpha dose-dependently enhanced the production of superoxide induced by NaF, as determined by the superoxide dismutase-inhibitable reduction of ferricytochrome c. Carbon 82-83 colony stimulating factor 2 Homo sapiens 40-46 16544270-6 2006 The derepression of P(CRD1)-lacZ expression by non-fermentable carbon sources was dependent on mitochondrial respiration. Carbon 63-69 cardiolipin synthase Saccharomyces cerevisiae S288C 22-26 2170519-3 1990 We therefore compared the ability of three naturally occurring PAF species (C16:0, C18:0, and C18:1), which only varied at carbon 1, to induce 51Cr-labeled human neutrophil migration across a naked 3-microns pore filter and human umbilical vein endothelial (HUVE) monolayers cultured on these filters. Carbon 123-129 PCNA clamp associated factor Homo sapiens 63-66 2085676-4 1990 Changes to the progesterone structure at C-17, C-20, or C-21 interfered with binding. Carbon 0-1 cytokine like 1 Homo sapiens 41-45 2236013-7 1990 The ga5 mutant had reduced levels of the C19-GAs, which indicates that the product of the GA5 gene catalyzes the elimination of C-20 at the aldehyde level. Carbon 41-42 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Arabidopsis thaliana 4-7 2236013-7 1990 The ga5 mutant had reduced levels of the C19-GAs, which indicates that the product of the GA5 gene catalyzes the elimination of C-20 at the aldehyde level. Carbon 41-42 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Arabidopsis thaliana 90-93 2236013-8 1990 The ga5 mutant also had increased levels of certain C20-GAs, which indicates existence of an additional control, possibly hydroxylation of C-20. Carbon 52-53 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Arabidopsis thaliana 4-7 1979651-2 1990 In association with this technique micro carbon fibre electrodes (CFE) are able to separate ascorbic acid (Peak 1) from 3,4-dihydroxyphenylacetic acid (DOPAC) plus dopamine (DA) (Peak 2) and 5-hydroxyindoleacetic acid (5-HIAAA) plus serotonin (5-HT) (Peak 3) in vitro. Carbon 41-47 pseudopodium-enriched atypical kinase 1 Mus musculus 107-113 2326537-5 1990 Forty two months postimplantation chronic threshold (measured at 0.5 msec pulse-width) was 1.6 +/- 0.6 V for platinum electrodes and 1 +/- 0.3 V for 12 mm2 carbon tip leads (p less than 0.001). Carbon 156-162 TOR signaling pathway regulator Homo sapiens 163-166 2326537-8 1990 The new activated carbon tip leads have lower chronic pacing thresholds than platinum electrodes with the same pacing area. Carbon 18-24 TOR signaling pathway regulator Homo sapiens 25-28 33777935-9 2021 Therefore, expedited citrate efflux from cholesterol-enriched tumor mitochondria via the CTP/SLC25A1 citrate transporter is fundamental for sustaining the constant demand for cytosolic citrate that fuels the elevated flow of carbons from acetyl-CoA through the deregulated pathway of cholesterol biosynthesis. Carbon 225-232 solute carrier family 25 member 1 Homo sapiens 89-92 33777935-9 2021 Therefore, expedited citrate efflux from cholesterol-enriched tumor mitochondria via the CTP/SLC25A1 citrate transporter is fundamental for sustaining the constant demand for cytosolic citrate that fuels the elevated flow of carbons from acetyl-CoA through the deregulated pathway of cholesterol biosynthesis. Carbon 225-232 solute carrier family 25 member 1 Homo sapiens 93-100 1583866-9 1992 These results indicate that measurement of FAO and FALDH activities in cultured skin fibroblasts using 18-carbon substrates is useful for SLS carrier detection. Carbon 105-112 aldehyde dehydrogenase 3 family member A2 Homo sapiens 51-56 26019148-3 2015 The FAT1 deletion mutant exhibited decreased growth on n-alkanes of 10-18 carbons, whereas the FAA1 mutant showed growth reduction on n-alkane of 16 carbons. Carbon 149-156 long-chain fatty acid-CoA ligase FAA1 Saccharomyces cerevisiae S288C 95-99 1799290-2 1991 Maltodextrins and hydrolysates of rice and corn flour of varying dextrose equivalents (DE) have been used as a carbon source for alpha-amylase enzyme production by Bacillus sp. Carbon 111-117 alpha-amylase Zea mays 129-142 34986438-8 2022 The electroactive GBP was immobilized onto gold nanoparticle-modified, polymerized caffeic acid, screen-printed carbon electrodes (GBP-LDOPA/AuNP/PCA/SPCE) for the purpose of direct measurement of glucose levels and serves as a proof-of-concept of the use of electrochemically-active unnatural amino acids as the label. Carbon 112-118 transmembrane protein 132A Homo sapiens 18-21 1776363-3 1991 Among them the rvs161 mutant (RVS for Reduced Viability upon Starvation) is sensitive to carbon, nitrogen and sulphur starvation. Carbon 89-95 amphiphysin-like protein RVS161 Saccharomyces cerevisiae S288C 15-21 34758919-0 2022 In-situ generated NiCo2O4/CoP polyhedron with rich oxygen vacancies interpenetrating by P-doped carbon nanotubes for high performance supercapacitors. Carbon 96-102 caspase recruitment domain family member 16 Homo sapiens 26-29 1888328-10 1991 When incorporation of [18O] from water catalyzed by cytosolic epoxide hydrolase was measured, the (2S,3S)-enantiomer gave 12% incorporation into the benzylic carbon and the (2R,3R)-enantiometer gave 40% incorporation into the benzylic carbon. Carbon 158-164 epoxide hydrolase 2, cytoplasmic Mus musculus 52-79 1888328-10 1991 When incorporation of [18O] from water catalyzed by cytosolic epoxide hydrolase was measured, the (2S,3S)-enantiomer gave 12% incorporation into the benzylic carbon and the (2R,3R)-enantiometer gave 40% incorporation into the benzylic carbon. Carbon 235-241 epoxide hydrolase 2, cytoplasmic Mus musculus 52-79 34861502-11 2022 On the other hand, low particulates removal and total carbon redirection were observed in the AAA-2. Carbon 54-60 AAA2 Homo sapiens 94-99 1657457-0 1991 Effects of dimethyl sulfoxide (DMSO) on carbon (CCL4)-induced hepatotoxicity in mice. Carbon 40-46 chemokine (C-C motif) ligand 4 Mus musculus 48-52 34563900-0 2022 Comprehensive evaluation of the carbon footprint components of wastewater treatment plants located in the Baltic Sea region. Carbon 32-38 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 113-116 2068275-4 1991 The phenanthridine group with a three-carbon side chain, P-1, was also synthesized to allow studies on the effect of the targeting group by itself. Carbon 38-44 crystallin gamma F, pseudogene Homo sapiens 57-60 34536862-8 2022 On the contrary, the soil recalcitrant carbon (RP-C) did not vary much across the wetland soils. Carbon 39-45 protein phosphatase 2 catalytic subunit alpha Homo sapiens 47-51 1997179-5 1991 The remaining efflux of this folate analogue in ATP-replete cells appears to be mediated by the one-carbon, reduced folate system (MTX influx route), in that it is not inhibited by bromosulfophthalein or verapamil but is inhibited by the N-hydroxysuccinimide ester of MTX, a specific inhibitor of MTX influx, and a 10-fold higher concentration of probenecid than that required to inhibit ATP-dependent efflux. Carbon 100-106 metaxin 1 Mus musculus 131-134 34857143-2 2022 In this work, morphology-controlled Cu-Sn alloy nanosheet arrays supported on carbon fiber paper (CP) substrate (Cu-Sn/CP) have been developed by a facile one-step electrodeposition technique at room temperature for the first time. Carbon 78-84 ceruloplasmin Homo sapiens 98-100 1990285-7 1991 Having proposed that regulation of 3" end formation dictates the amount of each CBP1 transcript, we now show that a 146-bp fragment from the middle of CBP1 is sufficient to direct carbon source-regulated production of two transcripts when inserted into the yeast URA3 gene. Carbon 180-186 Cbp1p Saccharomyces cerevisiae S288C 80-84 1990285-7 1991 Having proposed that regulation of 3" end formation dictates the amount of each CBP1 transcript, we now show that a 146-bp fragment from the middle of CBP1 is sufficient to direct carbon source-regulated production of two transcripts when inserted into the yeast URA3 gene. Carbon 180-186 Cbp1p Saccharomyces cerevisiae S288C 151-155 34857143-2 2022 In this work, morphology-controlled Cu-Sn alloy nanosheet arrays supported on carbon fiber paper (CP) substrate (Cu-Sn/CP) have been developed by a facile one-step electrodeposition technique at room temperature for the first time. Carbon 78-84 ceruloplasmin Homo sapiens 113-121 34962378-0 2022 MOF-on-MOF Strategy to Construct a Nitrogen-Doped Carbon-Incorporated CoP@Fe-CoP Core-Shelled Heterostructure for High-Performance Overall Water Splitting. Carbon 50-56 caspase recruitment domain family member 16 Homo sapiens 70-73 1937867-2 1991 At concentrations above 1 microM, PAF dose-dependently enhanced IL-6 production; at 5 microM PAF this increase (72.7 +/- 19.9 U/ml) was higher than that evoked by 100 U/ml IL-1 beta (5.7 +/- 0.4 U/ml) or 50 micrograms/ml poly-I:C (39.3 +/- 6.7 U/ml). Carbon 228-229 patchy fur Mus musculus 34-37 1937867-2 1991 At concentrations above 1 microM, PAF dose-dependently enhanced IL-6 production; at 5 microM PAF this increase (72.7 +/- 19.9 U/ml) was higher than that evoked by 100 U/ml IL-1 beta (5.7 +/- 0.4 U/ml) or 50 micrograms/ml poly-I:C (39.3 +/- 6.7 U/ml). Carbon 228-229 patchy fur Mus musculus 93-96 34962378-0 2022 MOF-on-MOF Strategy to Construct a Nitrogen-Doped Carbon-Incorporated CoP@Fe-CoP Core-Shelled Heterostructure for High-Performance Overall Water Splitting. Carbon 50-56 caspase recruitment domain family member 16 Homo sapiens 77-80 34962378-2 2022 Herein, we prepared nitrogen-doped carbon-incorporated CoP@Fe-CoP core-shelled nanorod arrays grown on Ni foam (CoP@Fe-CoP/NC/NF) through phosphorization of ZIF-67@Co-Fe Prussian blue analogue (ZIF-67@CoFe-PBA). Carbon 35-41 caspase recruitment domain family member 16 Homo sapiens 55-58 1811758-6 1991 The HAL DIRS-C was found to be sensitive to clinical change across weekly administrations. Carbon 12-14 histidine ammonia-lyase Homo sapiens 4-7 34962378-2 2022 Herein, we prepared nitrogen-doped carbon-incorporated CoP@Fe-CoP core-shelled nanorod arrays grown on Ni foam (CoP@Fe-CoP/NC/NF) through phosphorization of ZIF-67@Co-Fe Prussian blue analogue (ZIF-67@CoFe-PBA). Carbon 35-41 caspase recruitment domain family member 16 Homo sapiens 62-65 2014004-4 1991 SHMT catalyses the biosynthesis of glycine from serine and the transfer of a one-carbon unit to tetrahydrofolate. Carbon 81-87 serine hydroxymethyltransferase Glycine max 0-4 34962378-2 2022 Herein, we prepared nitrogen-doped carbon-incorporated CoP@Fe-CoP core-shelled nanorod arrays grown on Ni foam (CoP@Fe-CoP/NC/NF) through phosphorization of ZIF-67@Co-Fe Prussian blue analogue (ZIF-67@CoFe-PBA). Carbon 35-41 caspase recruitment domain family member 16 Homo sapiens 112-115 34962378-2 2022 Herein, we prepared nitrogen-doped carbon-incorporated CoP@Fe-CoP core-shelled nanorod arrays grown on Ni foam (CoP@Fe-CoP/NC/NF) through phosphorization of ZIF-67@Co-Fe Prussian blue analogue (ZIF-67@CoFe-PBA). Carbon 35-41 caspase recruitment domain family member 16 Homo sapiens 119-122 2118902-3 1990 The dual specificity considered here is typified by the oxygenation of arachidonic acid by the reticulocyte lipoxygenase: two chiral products are formed (12S- and 15S-hydroperoxides, ratio approximately 1:9) via hydrogen abstraction from two separate methylene groups (C-10 and C-13). Carbon 278-279 linoleate 9S-lipoxygenase-4 Glycine max 108-120 34523468-10 2022 These results indicate that utilisation of local organic carbon-containing wastes for coverage of coal waste rock may be a cost-effective strategy to reduce Se leaching to acceptable rates of release regardless of whether the Se is associated with framboidal pyrite or organics. Carbon 57-63 squalene epoxidase Homo sapiens 157-159 2133093-4 1990 A comparison with the corresponding values for the monoamine oxidase B (MAO-B) catalyzed reaction (4.37 and 9.35, respectively) suggests that either these enzymes catalyze the ring alpha-carbon oxidation of MPTP by different pathways or that the initial one-electron transfer to generate an aminium radical intermediate previously proposed for both enzyme systems is reversible in the case of MAO-B and irreversible in the case of cytochrome P-450IA1. Carbon 187-193 monoamine oxidase B Rattus norvegicus 51-70 2133093-4 1990 A comparison with the corresponding values for the monoamine oxidase B (MAO-B) catalyzed reaction (4.37 and 9.35, respectively) suggests that either these enzymes catalyze the ring alpha-carbon oxidation of MPTP by different pathways or that the initial one-electron transfer to generate an aminium radical intermediate previously proposed for both enzyme systems is reversible in the case of MAO-B and irreversible in the case of cytochrome P-450IA1. Carbon 187-193 monoamine oxidase B Rattus norvegicus 72-77 16491469-1 2006 The pet20-delta deletion in Saccharomyces cerevisiae causes diminished growth on media containing non-fermentable carbon sources when incubated at both above and below the 30 degrees C optimal growth temperature. Carbon 114-120 Pet20p Saccharomyces cerevisiae S288C 4-9 2133093-4 1990 A comparison with the corresponding values for the monoamine oxidase B (MAO-B) catalyzed reaction (4.37 and 9.35, respectively) suggests that either these enzymes catalyze the ring alpha-carbon oxidation of MPTP by different pathways or that the initial one-electron transfer to generate an aminium radical intermediate previously proposed for both enzyme systems is reversible in the case of MAO-B and irreversible in the case of cytochrome P-450IA1. Carbon 187-193 monoamine oxidase B Rattus norvegicus 393-398 34863066-6 2022 PPAR transactivation activity demonstrated that the seven-carbon side chain analogs (series 1) displayed selectivity for hPPARalpha, while the nine-carbon side chain analogs (polycerasoidol analogs, series 2) did so for hPPARgamma. Carbon 148-154 peroxisome proliferator activated receptor alpha Homo sapiens 0-4 34764205-0 2022 The protein kinase activity of NME7 activates Wnt/beta-Catenin signaling to promote one-carbon metabolism in hepatocellular carcinoma. Carbon 88-94 catenin beta 1 Homo sapiens 50-62 34764205-8 2022 Furthermore, MTHFD2, the key enzyme in one-carbon metabolism, was a target gene of beta-catenin and mediated the effects of NME7. Carbon 43-49 NME/NM23 family member 7 Mus musculus 124-128 2369741-5 1990 Alkylation of aminopterin (methotrexate) or carbon for nitrogen substitution (10-deazaaminopterin) at N-10 increased Km 3- to 6-fold, while alkylation at C10 (10-ethyl-10-deazaaminopterin) restored Km to near equivalency with aminopterin. Carbon 44-50 gene rich cluster, C10 gene Mus musculus 154-157 34974038-8 2022 Furthermore, a reaction mechanism function in model fly ash was built as f(alpha)=2alpha-1/2/3, which included carbon gasification and de novo synthesis. Carbon 111-117 mir-2a-1 stem loop Drosophila melanogaster 82-94 24420275-1 1990 "Photosynthetic control" describes the processes that serve to modify chloroplast membrane reactions in order to co-ordinate the synthesis of ATP and NADPH with the rate at which these metabolites can be used in carbon metabolism. Carbon 212-218 2,4-dienoyl-CoA reductase 1 Homo sapiens 150-155 34952627-0 2021 Carbon catabolite repression involves physical interaction of the transcription factor CRE1/CreA and the Tup1-Cyc8 complex in Penicillium oxalicum and Trichoderma reesei. Carbon 0-6 Spt10p Saccharomyces cerevisiae S288C 87-91 2224895-3 1990 Thus, with three reactive substituents (at O-2,3,5), the corresponding glycosides (1 and 7) underwent a novel internal bis-C-arylation process, which involved successive alkylations of the benzyl groups at O-2 and O-3 ("multiple participation"), leading to the formal replacement of the two C-O bonds at the anomeric center of the glycoside by two C-C bonds. Carbon 123-124 immunoglobulin kappa variable 1D-39 Homo sapiens 206-217 34952902-2 2021 Herein, a highly effective self-detoxifying filter consisting of in-situ immobilized Zirconium hydroxide (Zr(OH)4) over woven activated carbon fabric (Zr(OH)4@W-ACF) is presented for the removal of CWAs. Carbon 136-142 ACF Homo sapiens 161-164 2393551-5 1990 If U-13C-glucose is used and recycling of isotope not quantitated, the resulting calculated value for Ra glucose will represent the rate of production from non-recycled carbons, plus some recycled carbons, due to potential dilution of 13C in the oxaloacetate pool and some loss of 13C in the PEPCK reaction. Carbon 169-176 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 292-297 2393551-5 1990 If U-13C-glucose is used and recycling of isotope not quantitated, the resulting calculated value for Ra glucose will represent the rate of production from non-recycled carbons, plus some recycled carbons, due to potential dilution of 13C in the oxaloacetate pool and some loss of 13C in the PEPCK reaction. Carbon 197-204 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 292-297 34866388-4 2021 The negative electrode is prepared from hierarchically porous active carbon mixed with CNTs (PICK-CNTs). Carbon 69-75 protein interacting with PRKCA 1 Homo sapiens 93-97 34649153-0 2021 Hepatoprotective, antioxidant and anti-inflammatory potentials of Vit-E/C@SeNPs in rats: Synthesis, characterization, biochemical, radio-biodistribution, molecular and histopathological studies. Carbon 72-73 vitrin Rattus norvegicus 66-69 1970993-6 1990 The cis-syn stereoconfiguration of the two photocycloadducts was inferred from coupling constant considerations and on the basis of the complete assignment of the cyclobutyl protons, requiring the synthesis of deuterated nucleosides at pyrimidine carbon C(6). Carbon 247-255 synemin Homo sapiens 8-11 34739983-8 2021 We found that the alpha-synuclein gene is the key factor in carbon-induced abnormal neuronal function. Carbon 60-66 synuclein alpha Homo sapiens 18-33 34560994-6 2021 Filtration test of separating carbon nanofibers and carbon nanotubes from water demonstrated the potential use of the CP/PEO nanofiber mats in fluid filtration of fibrous pollutants. Carbon 30-36 ceruloplasmin Homo sapiens 118-120 34951281-5 2021 Compared with CK, ST3 and ST4 treatments significantly increased the content of mineral-bound organic carbon (MOC) in 250-2000 mum aggregates and the content of fine particulate organic carbon (fPOC) in 53-250 mum aggregates. Carbon 102-108 tumor-suppressor, HELA cell type Homo sapiens 18-21 34951281-5 2021 Compared with CK, ST3 and ST4 treatments significantly increased the content of mineral-bound organic carbon (MOC) in 250-2000 mum aggregates and the content of fine particulate organic carbon (fPOC) in 53-250 mum aggregates. Carbon 102-108 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 Homo sapiens 26-29 34951281-5 2021 Compared with CK, ST3 and ST4 treatments significantly increased the content of mineral-bound organic carbon (MOC) in 250-2000 mum aggregates and the content of fine particulate organic carbon (fPOC) in 53-250 mum aggregates. Carbon 186-192 tumor-suppressor, HELA cell type Homo sapiens 18-21 34951281-5 2021 Compared with CK, ST3 and ST4 treatments significantly increased the content of mineral-bound organic carbon (MOC) in 250-2000 mum aggregates and the content of fine particulate organic carbon (fPOC) in 53-250 mum aggregates. Carbon 186-192 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 Homo sapiens 26-29 34846780-1 2022 We merge the synthesis of electrocatalyst and the electrode preparation into one-step process, and report a versatile method to synthesize metal oxide electrocatalysts on the conductive carbon paper (CP). Carbon 186-192 ceruloplasmin Homo sapiens 200-202 34747596-0 2021 Carbon Nanotube Field-Effect Transistor Biosensor for Ultrasensitive and Label-Free Detection of Breast Cancer Exosomal miRNA21. Carbon 0-6 microRNA 21 Homo sapiens 120-127 34901668-4 2021 The as-synthesized porous carbon (PC-1) holds the natural texture property (the retention of texture property with apertures higher than 2 nm was up to 80%) and achieves three-dimensional (3D) architecture with hierarchical structures accompanied by an ultrahigh specific surface area (3559.45 m2/g). Carbon 26-32 proprotein convertase subtilisin/kexin type 1 Homo sapiens 34-38 34730347-2 2021 Here we synthesized a series of supported Pt1 SACs by depositing Pt atoms onto the pretuned anchoring sites on nitrogen-doped carbon using atomic layer deposition. Carbon 126-132 zinc finger protein 77 Homo sapiens 42-45 34732697-10 2021 Here, the use of carbon ion beams (5 GyE) for melanoma-bearing mice was found to reduce the population of MDSC in the bone marrow, peripheral blood, and spleen of the animals via a JAK2/STAT3-dependent mechanism. Carbon 17-23 Janus kinase 2 Mus musculus 181-185 34732822-0 2021 Sea ice presence is linked to higher carbon export and vertical microbial connectivity in the Eurasian Arctic Ocean. Carbon 37-43 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 0-3 34732822-2 2021 Long-term sediment trap data shows higher export efficiency of particulate organic carbon in regions with seasonal sea ice compared to regions without sea ice. Carbon 83-89 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 115-118 34666490-0 2021 Investigation of the Failure of the MP2 Method to Describe the Out-of-Plane Bending Motions of Carbon-Carbon Double-Bonded Molecules: The Role of Atomic Orbitals. Carbon 95-101 tryptase pseudogene 1 Homo sapiens 36-39 34666490-0 2021 Investigation of the Failure of the MP2 Method to Describe the Out-of-Plane Bending Motions of Carbon-Carbon Double-Bonded Molecules: The Role of Atomic Orbitals. Carbon 102-108 tryptase pseudogene 1 Homo sapiens 36-39 34459044-2 2021 We have discovered a high-yielding P=C bond metathesis of phosphaalkenes (ArP=CPh 2 , Ar = Mes, o -Tol, Ph) that is catalyzed by N-heterocyclic carbenes (NHC = Me 2 IMe, Me 2 I i Pr). Carbon 37-38 mesencephalic astrocyte derived neurotrophic factor Homo sapiens 74-77 34723019-6 2021 It was found that the addition of the nitrogen dopant improved the MSI by promoting electronic rearrangement from the metals" d- to s-orbitals for greater orbital overlap with the carbon support, shown with increased favorable adsorption. Carbon 180-186 RB binding protein 4, chromatin remodeling factor Homo sapiens 67-70 34642537-0 2022 Effect of heat treatment on the morphology of carbon fibers doped with Co2p nanoparticles. Carbon 46-52 complement C2 Homo sapiens 71-75 16531331-2 2006 Here we show that phagocytosis of colloidal carbon by marginal zone macrophages results in a splenic influx of B lymphocytes, and T lymphocytes of memory/activated phenotype, with concomitant upregulation of B Lymphocyte Chemoattractant (BLC, CXCL13) mRNA, a chemokine acting on B and memory/activated T lymphocytes. Carbon 44-50 chemokine (C-X-C motif) ligand 13 Mus musculus 208-236 16531331-2 2006 Here we show that phagocytosis of colloidal carbon by marginal zone macrophages results in a splenic influx of B lymphocytes, and T lymphocytes of memory/activated phenotype, with concomitant upregulation of B Lymphocyte Chemoattractant (BLC, CXCL13) mRNA, a chemokine acting on B and memory/activated T lymphocytes. Carbon 44-50 chemokine (C-X-C motif) ligand 13 Mus musculus 238-241 16531331-2 2006 Here we show that phagocytosis of colloidal carbon by marginal zone macrophages results in a splenic influx of B lymphocytes, and T lymphocytes of memory/activated phenotype, with concomitant upregulation of B Lymphocyte Chemoattractant (BLC, CXCL13) mRNA, a chemokine acting on B and memory/activated T lymphocytes. Carbon 44-50 chemokine (C-X-C motif) ligand 13 Mus musculus 243-249 34601503-3 2021 Herein, we report that metformin treatment increases the sensitivity of hepatocarcinoma cells to methotrexate (MTX) by suppressing the expression of the one-carbon metabolism enzyme DHFR. Carbon 157-163 dihydrofolate reductase Homo sapiens 182-186 16484076-7 2006 The degradation rate of n-alkanes with carbon numbers ranging from C10 to C15 was relatively greater than that of n-alknaes with carbon numbers ranging from C16 to C20. Carbon 39-45 placenta associated 8 Homo sapiens 74-77 34101628-11 2021 IL-32beta/gamma/epsilon isoform mRNA were detected in HT-29 cells upon exposure to TNF-alpha, Poly I:C (TLR3 agonist), Flagellin (TLR-5 agonist) and HIV. Carbon 101-102 interleukin 32 Homo sapiens 0-9 16508071-3 2006 The carbon ink electrodes are modified with methylene green and alcohol dehydrogenase immobilized within a modified Nafion membrane to act as bioanodes in the microfluidic system. Carbon 4-10 aldo-keto reductase family 1 member A1 Homo sapiens 64-85 16260018-6 2006 At 8 h after initial dosing, brain cholinesterase inhibition was significantly greater in the C/P group (59%) compared to the P/C group (28%). Carbon 94-95 butyrylcholinesterase Rattus norvegicus 35-49 16260018-6 2006 At 8 h after initial dosing, brain cholinesterase inhibition was significantly greater in the C/P group (59%) compared to the P/C group (28%). Carbon 128-129 butyrylcholinesterase Rattus norvegicus 35-49 34101628-12 2021 IL-17A significantly decreased both IL-32 beta/gamma/epsilon mRNA and cell-associated IL-32 protein levels induced upon TNF-alpha and Poly I:C triggering. Carbon 141-142 interleukin 32 Homo sapiens 36-91 34162101-1 2021 In this study, granular activated carbon (GAC) was examined for the removal of five of the most commonly detected pharmaceuticals (naproxen, carbamazepine, acetaminophen, ibuprofen and metronidazole) from a nitrified urine to make the urine-derived fertiliser nutrient safe for food crops. Carbon 34-40 glutaminase Homo sapiens 42-45 16475356-7 2005 This study indicates that carbon, such as oil-sand fluid coke, can be utilized to remove SO2 in flue gases containing O2/H2O and to convert it to elemental sulfur. Carbon 26-32 immunoglobulin kappa variable 1D-39 Homo sapiens 118-124 16185646-6 2005 In addition, NO-based modifications of proteins and peptides on nonsulfur groups (e.g., carbon, oxygen, nitrogen) are detected on DAF gels. Carbon 88-94 CD55 molecule (Cromer blood group) Homo sapiens 130-133 34418740-4 2021 The results indicated that the addition of steam could dramatically facilitate the decomposition and reduction process of spent NCM, and the carbon removal efficiency could reach 84%. Carbon 141-147 CWC22 spliceosome associated protein homolog Homo sapiens 128-131 34525143-0 2021 Understanding the close encounter of heme proteins with carboxylated multiwalled carbon nanotubes: a case study of contradictory stability trend for hemoglobin and myoglobin. Carbon 81-87 myoglobin Homo sapiens 164-173 16358787-5 2005 As a result, atoms C-3 and C-4 of glucose become enriched with the heavy isotope, and subsequent mixing of atoms and the specificity of interactions in the photorespiration chain lead to an isotope weighting of the other atoms and an uneven distribution of carbon isotopes in glucose-6-phosphate and other photorespiration products. Carbon 257-263 complement C3 Homo sapiens 19-22 16260593-2 2005 We demonstrate that the ARE-bearing MFA2 3" untranslated region (UTR) controls translation efficiency in a p38 MAPK/Hog1p-dependent manner in response to carbon source growth conditions. Carbon 154-160 mating pheromone a Saccharomyces cerevisiae S288C 36-40 16260593-3 2005 The carbon source-regulated effect on MFA2 3"-UTR-controlled translation involves the role of conserved ARE binding proteins, the ELAV/TIA-1-like Pub1p, which can interact with the cap/eIF4G complex, and the translation/mRNA stability factor poly(A) binding protein (Pab1p). Carbon 4-10 mating pheromone a Saccharomyces cerevisiae S288C 38-42 16260593-3 2005 The carbon source-regulated effect on MFA2 3"-UTR-controlled translation involves the role of conserved ARE binding proteins, the ELAV/TIA-1-like Pub1p, which can interact with the cap/eIF4G complex, and the translation/mRNA stability factor poly(A) binding protein (Pab1p). Carbon 4-10 polyadenylate-binding protein Saccharomyces cerevisiae S288C 267-272 16260593-4 2005 Pub1p binds the MFA2 3"-UTR in a p38 MAPK/Hog1p-regulated manner in response to carbon source growth conditions. Carbon 80-86 mating pheromone a Saccharomyces cerevisiae S288C 16-20 16260593-5 2005 Significantly, the p38 MAPK/Hog1p is also required to modulate Pab1p in response to carbon source. Carbon 84-90 polyadenylate-binding protein Saccharomyces cerevisiae S288C 63-68 16260593-8 2005 Importantly, Pab1p binds the MFA2 3"-UTR only in a PUB1 strain, and correlating with this requirement, Pub1p controls translation repression of MFA2 in a carbon source/Hog1p-regulated manner. Carbon 154-160 polyadenylate-binding protein Saccharomyces cerevisiae S288C 13-18 16260593-8 2005 Importantly, Pab1p binds the MFA2 3"-UTR only in a PUB1 strain, and correlating with this requirement, Pub1p controls translation repression of MFA2 in a carbon source/Hog1p-regulated manner. Carbon 154-160 mating pheromone a Saccharomyces cerevisiae S288C 144-148 34612415-2 2021 Recently, a new stable two-dimensional carbon allotrope, namely PAI-graphene, was reported by first-principles calculations. Carbon 39-45 serpin family E member 1 Homo sapiens 64-67 2136896-8 1990 Similarly, FcRIII on NK cells was resistant to glycosyl-phosphatidyl-inositol-specific phospholipase C treatment, suggesting that NK cell FcRIII is also not anchored by a phosphatidyl-inositol-glycan moiety, in contrast to neutrophil FcRIII. Carbon 101-102 Fc gamma receptor IIIa Homo sapiens 11-17 33775647-8 2021 Furthermore, the result from DiI-LDL uptake assay under the knockdown of PCSK9 demonstrated that miR-337-3p promoting the absorption of LDL-C in HepG2 cells was dependent on PCSK9, and the result from LDLR-/- mouse model indicated that miR-337-3p regulating LDL-C was dependent on PCSK9/LDLR pathway. Carbon 139-141 microRNA 337 Mus musculus 97-104 33775647-8 2021 Furthermore, the result from DiI-LDL uptake assay under the knockdown of PCSK9 demonstrated that miR-337-3p promoting the absorption of LDL-C in HepG2 cells was dependent on PCSK9, and the result from LDLR-/- mouse model indicated that miR-337-3p regulating LDL-C was dependent on PCSK9/LDLR pathway. Carbon 139-141 low density lipoprotein receptor Mus musculus 287-291 15978607-1 2005 Adsorption and electrosorption of thiocyanate (SCN-) anions on active carbon felt electrodes were measured by UV spectroscopy and cyclic voltammetry to provide more knowledge of the application of electrosorption on high-area carbon material in industrial waste water purification. Carbon 70-76 sorcin Homo sapiens 47-50 34579420-1 2021 Phosphoenolpyruvate carboxylase (PEPC) is a ubiquitous cytosolic enzyme, which is crucial for plant carbon metabolism. Carbon 100-106 phosphoenolpyruvate carboxykinase 1 Homo sapiens 0-31 16183870-11 2005 In addition, the CD200+ CK7+ percentage was significantly lower in trophoblast cells incubated with poly (I:C) at a certain concentration, in vitro, while histocytochemical examination showed the CD200+ cells mainly scattered in placental tissue adjacent to the interface of the placenta and uterus. Carbon 17-18 keratin 7 Mus musculus 24-27 33806844-3 2021 In this paper, CF/carbon felt (CF/C felt) was fabricated by CF and phenolic resin using the "airflow network method", "needle-punching method" and "graphitization process method". Carbon 18-24 tubulin folding cofactor C Homo sapiens 31-35 33806675-0 2021 SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine-Glycine-One-Carbon Pathways in Cancer. Carbon 68-74 solute carrier family 6 member 14 Homo sapiens 0-7 16094485-2 2005 as Si(NN)] into the carbon-halogen bond of alkyl or aryl halides RHal (Hal=Cl, Br). Carbon 20-26 histidine ammonia-lyase Homo sapiens 66-69 34579420-1 2021 Phosphoenolpyruvate carboxylase (PEPC) is a ubiquitous cytosolic enzyme, which is crucial for plant carbon metabolism. Carbon 100-106 phosphoenolpyruvate carboxykinase 1 Homo sapiens 33-37 34577956-0 2021 Impact Toughness of Hybrid Carbon Fiber-PLA/ABS Laminar Composite Produced through Fused Filament Fabrication. Carbon 27-33 DEAD-box helicase 41 Homo sapiens 44-47 15964170-1 2005 Folate, methionine, betaine, choline, zinc and Vitamins B(12), B(6) and B(2) are involved in one-carbon metabolism, which includes S-adenosylmethionine (SAM) substrated methylation. Carbon 97-103 immunoglobulin kappa variable 5-2 Homo sapiens 72-76 32794861-0 2020 Topologically Protected Correlated End Spin Formation in Carbon Nanotubes. Carbon 57-63 spindlin 1 Homo sapiens 39-43 34270157-4 2021 Using a b -lactamase binding protein (BLIP2) as the capture protein attached to carbon nanotube field effect transistors in different defined orientations, device conductance was influenced on binding TEM-1, an important b -lactamase involved in antimicrobial resistance (AMR). Carbon 80-86 CD248 molecule Homo sapiens 201-206 34801300-6 2022 The absolute abundance of ARGs at 30 days was 1.29 x 1012 and 1.07 x 1012 copies for carbon and surgical masks, respectively. Carbon 85-91 serpin family A member 2 (gene/pseudogene) Homo sapiens 26-30 16086935-8 2005 In the vitamin E and C, group there was reduction in serum ICAM-1 (298 +/- 12 to 272 +/- 12 ng/mL at 6 months, P = .0015) with a return to base line 6 months after cessation of therapy. Carbon 21-22 intercellular adhesion molecule 1 Homo sapiens 59-65 34578617-0 2021 Effect of Multi-Walled Carbon Nanotubes-Based Nanofluids on Marine Gas Turbine Intercooler Performance. Carbon 23-29 gastrin Homo sapiens 67-70 34890952-2 2022 Herein, a facile strategy was first proposed that zero-dimensional Fe/Fe3C nanoparticles were embedded in one-dimensional N-doped carbon nanofiber (Fe/Fe3C@NCNF) to solve the above challenges. Carbon 130-136 general transcription factor IIE subunit 1 Homo sapiens 67-69 34890952-2 2022 Herein, a facile strategy was first proposed that zero-dimensional Fe/Fe3C nanoparticles were embedded in one-dimensional N-doped carbon nanofiber (Fe/Fe3C@NCNF) to solve the above challenges. Carbon 130-136 general transcription factor IIE subunit 1 Homo sapiens 148-150 34785051-0 2022 Hollow carbon spheres loaded with NiSe2 nanoplates as multifunctional SeS2 hosts for Li-SeS2 batteries. Carbon 7-13 secernin 2 Homo sapiens 70-74 34785051-0 2022 Hollow carbon spheres loaded with NiSe2 nanoplates as multifunctional SeS2 hosts for Li-SeS2 batteries. Carbon 7-13 secernin 2 Homo sapiens 88-92 34785051-2 2022 Therefore, in this work, hollow carbon spheres loaded with NiSe2 nanoplates were prepared as SeS2 hosts for Li-SeS2 batteries. Carbon 32-38 secernin 2 Homo sapiens 93-97 34785051-2 2022 Therefore, in this work, hollow carbon spheres loaded with NiSe2 nanoplates were prepared as SeS2 hosts for Li-SeS2 batteries. Carbon 32-38 secernin 2 Homo sapiens 111-115 15984831-6 2005 Density functional studies show that a plausible mechanism involves the metal center "walking" around the pi-system from the bridging C=C double bond to the C-Br bond. Carbon 134-135 carbonyl reductase 1 Homo sapiens 157-161 15984831-6 2005 Density functional studies show that a plausible mechanism involves the metal center "walking" around the pi-system from the bridging C=C double bond to the C-Br bond. Carbon 136-137 carbonyl reductase 1 Homo sapiens 157-161 34785051-3 2022 The unique micro-mesoporous hollow carbon spheres not only provide channels for the diffusion of SeS2, but also afford spaces for alleviating the volume expansion of the active substance. Carbon 35-41 secernin 2 Homo sapiens 97-101 34101337-3 2021 The fluorescent behavior of C-1 upon the addition of Zn2+ or Cd2+ showed a "turn-on" response accompanied with fluorescence enhancement at 510 nm by 6 times for Cd2+ and by 13 times for Zn2+ . Carbon 28-29 CD2 molecule Homo sapiens 61-64 34101337-3 2021 The fluorescent behavior of C-1 upon the addition of Zn2+ or Cd2+ showed a "turn-on" response accompanied with fluorescence enhancement at 510 nm by 6 times for Cd2+ and by 13 times for Zn2+ . Carbon 28-29 CD2 molecule Homo sapiens 161-164 34844349-1 2022 Herein, novel magnetic nickel incorporated carbon nanofibers (Ni@CNF) were successfully synthesized via electrostatic spinning method for sulfadiazine (SDZ) adsorption. Carbon 43-49 NPHS1 adhesion molecule, nephrin Homo sapiens 65-68 34502147-4 2021 Strain A16 exhibited superior tetramethrin degradation activity, and utilized tetramethrin as the sole carbon source for growth in a mineral salt medium (MSM). Carbon 103-109 immunoglobulin kappa variable 3-31 (pseudogene) Homo sapiens 7-10 34953211-5 2022 Following 4-week injections of poly I:C, not only hepatic RIG-I, but also TLR3 and MDA5 showed female-predominance. Carbon 38-39 DEAD/H box helicase 58 Mus musculus 58-63 34953211-5 2022 Following 4-week injections of poly I:C, not only hepatic RIG-I, but also TLR3 and MDA5 showed female-predominance. Carbon 38-39 interferon induced with helicase C domain 1 Mus musculus 83-87 34416462-2 2022 In this article, a novel cobalt polysulfide/carbon nanofibers (C,N-CoxSy/CNF) film derived from zeolitic imidazolate framework is first prepared by a facile strategy. Carbon 44-50 NPHS1 adhesion molecule, nephrin Homo sapiens 73-76 15933197-1 2005 Liquid alkanes with the number of carbon atoms ranging from C7 to C15 were selectively produced from biomass-derived carbohydrates by acid-catalyzed dehydration, which was followed by aldol condensation over solid base catalysts to form large organic compounds. Carbon 34-40 placenta associated 8 Homo sapiens 66-69 15764712-5 2005 Five metabolites were detected in the metabolism of C3O1 and O2C3 by human CYP24A1 including both C-23 and C-24 oxidation pathways. Carbon 52-53 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 75-82 34338500-3 2021 Herein, we report a fluorine-enriched nitrogen-doped hollow carbon spheres decorated carbon fibers (FNCS@CF) skeleton which effectively integrates the uniformly distributed lithophilic sites and mechanically robust LiF-enriched SEI, thus endowing the composite Li metal anode with durable and dendrite-free features. Carbon 60-66 LIF interleukin 6 family cytokine Homo sapiens 215-218 15901697-17 2005 Thus, AtzF affects the cleavage of three carbon-to-nitrogen bonds via a mechanism similar to that of enzymes catalyzing single-amide-bond cleavage reactions. Carbon 41-47 atzF Pseudomonas sp. ADP 6-10 16852041-6 2005 Moreover, the SnO(2) nanoparticles were employed to synthesize carbon-supported PtSnO(2) catalyst, and it exhibits surprisingly high promoting catalytic activity for ethanol electrooxidation. Carbon 63-69 strawberry notch homolog 2 Homo sapiens 14-17 34767747-2 2022 We show that the one-carbon (1C) metabolism enzyme methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) regulates de novo purine synthesis and signaling in activated T cells to promote proliferation and inflammatory cytokine production. Carbon 21-27 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 51-92 34767747-2 2022 We show that the one-carbon (1C) metabolism enzyme methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) regulates de novo purine synthesis and signaling in activated T cells to promote proliferation and inflammatory cytokine production. Carbon 21-27 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 94-100 34338500-3 2021 Herein, we report a fluorine-enriched nitrogen-doped hollow carbon spheres decorated carbon fibers (FNCS@CF) skeleton which effectively integrates the uniformly distributed lithophilic sites and mechanically robust LiF-enriched SEI, thus endowing the composite Li metal anode with durable and dendrite-free features. Carbon 85-91 LIF interleukin 6 family cytokine Homo sapiens 215-218 34338500-5 2021 The fluorinated hollow carbon spheres can not only provide a powerful setting for Li deposition but can also promote the in situ formation of LiF-enriched SEI. Carbon 23-29 LIF interleukin 6 family cytokine Homo sapiens 142-145 34445349-2 2021 ALDP is associated with the transport of very-long-chain fatty acids (VLCFAs; carbon chain length >= 24) into peroxisomes. Carbon 78-84 ATP binding cassette subfamily D member 1 Homo sapiens 0-4 34959032-3 2022 Reduction of the heptono lactone with sodium borohydride followed by acetylation gives a peracetylated aminodeoxyheptitol 6 that adopts the zig zag conformation of its carbon backbone. Carbon 168-174 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 144-147 34311304-6 2022 The obtained Fe and N co-doped carbon back (Fe-N/CB) catalyst has very large specific surface area and abundant accessible Fe-Nx moieties. Carbon 31-37 FECB Homo sapiens 44-51 15974269-5 2005 However, the life-time of P25 Degussa at high phenol concentration was lower compared to that of anatase A11 because of the carbon deposit formation on P25 surface. Carbon 124-130 tubulin polymerization promoting protein Homo sapiens 26-29 15974269-5 2005 However, the life-time of P25 Degussa at high phenol concentration was lower compared to that of anatase A11 because of the carbon deposit formation on P25 surface. Carbon 124-130 tubulin polymerization promoting protein Homo sapiens 152-155 15974269-6 2005 The catalytic activity of rutile phase in P25 in the reaction of carbon deposits formation is postulated. Carbon 65-71 tubulin polymerization promoting protein Homo sapiens 42-45 34363545-7 2021 plantarum A16, A25, B11, and B15) showed the best traits, in particular strong antifungal activity and good capabilities to produce exopolysaccharides from different carbon sources in vitro. Carbon 166-172 NADH:ubiquinone oxidoreductase subunit B4 Homo sapiens 29-32 15867278-0 2005 The methylenetetrahydrofolate reductase 677C->T polymorphism and dietary folate restriction affect plasma one-carbon metabolites and red blood cell folate concentrations and distribution in women. Carbon 113-119 methylenetetrahydrofolate reductase Homo sapiens 4-39 15863701-5 2005 Measurements of photosynthesis, made under growth conditions integrated over the day, showed that mature plants with increased SBPase activity fixed 6% to 12% more carbon than equivalent wild-type leaves, with the young leaves having the highest rates. Carbon 164-170 sedoheptulose-bisphosphatase Arabidopsis thaliana 127-133 34786835-0 2022 Unveiling the Role and Mechanism of Nb Doping and In Situ Carbon Coating on Improving Lithium-Ion Storage Characteristics of Rod-Like Morphology FeF3 0.33H2 O. Carbon 58-64 kinetochore associated 1 Homo sapiens 125-128 34786835-3 2022 Herein, rod-like Nb-substituted FeF3 0.33H2 O (Nb-FeF3 0.33H2 O@C) nanocrystals with a carbon coating derived from in situ carbonization in an ionic liquid are deliberately designed and prepared. Carbon 89-95 kinetochore associated 1 Homo sapiens 8-11 34874284-1 2021 In this paper, a carbon nanofiber (CNF) hybrid nanomaterial composed of MnO-Sn cubes embedding in nitrogen-doped CNF (MnO-Sn@CNF) is synthesized through electrospinning and post-thermal reduction processes. Carbon 17-23 NPHS1 adhesion molecule, nephrin Homo sapiens 35-38 34874284-1 2021 In this paper, a carbon nanofiber (CNF) hybrid nanomaterial composed of MnO-Sn cubes embedding in nitrogen-doped CNF (MnO-Sn@CNF) is synthesized through electrospinning and post-thermal reduction processes. Carbon 17-23 NPHS1 adhesion molecule, nephrin Homo sapiens 113-116 34874284-1 2021 In this paper, a carbon nanofiber (CNF) hybrid nanomaterial composed of MnO-Sn cubes embedding in nitrogen-doped CNF (MnO-Sn@CNF) is synthesized through electrospinning and post-thermal reduction processes. Carbon 17-23 NPHS1 adhesion molecule, nephrin Homo sapiens 118-128 34445118-9 2021 As in CD8+ CTLs, cysteine cathepsins C and H were the major targets of cystatin F in CD4+ T-cell clones. Carbon 37-38 cystatin F Homo sapiens 71-81 34753066-5 2021 In this study, we aimed to examine the effects of DS18561882 (DS18), a novel, orally active, specific inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), a mitochondrial enzyme involved in one-carbon metabolism. Carbon 204-210 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 156-162 15853764-7 2005 Production of succinic acid by SSADH allows entry of the GABA carbon skeleton into the tricarboxylic acid cycle. Carbon 62-68 aldehyde dehydrogenase 5 family member A1 Homo sapiens 31-36 34288694-0 2021 N2 Gas Adsorption Sites of Single-Walled Carbon Nanotube Bundles: Identifying Interstitial Channels at Very Low Relative Pressure. Carbon 41-47 gastrin Homo sapiens 3-6 15770476-0 2005 Escherichia coli single-strand binding protein-DNA interactions on carbon nanotube-modified electrodes from a label-free electrochemical hybridization sensor. Carbon 67-73 single-strand binding protein Escherichia coli 17-46 15770476-2 2005 The voltammetric signal from guanine oxidation significantly decreased upon binding of SSB to single-stranded oligonucleotides (probe), anchored on a single-walled carbon nanotube (SWCNT) -modified screen-printed carbon electrode (SPE). Carbon 164-170 single-strand binding protein Escherichia coli 87-90 15770476-2 2005 The voltammetric signal from guanine oxidation significantly decreased upon binding of SSB to single-stranded oligonucleotides (probe), anchored on a single-walled carbon nanotube (SWCNT) -modified screen-printed carbon electrode (SPE). Carbon 213-219 single-strand binding protein Escherichia coli 87-90 34960114-1 2021 The 5-10-methylenetetrahydrofolate reductase (MTHFR) enzyme is vital for cellular homeostasis due to its key functions in the one-carbon cycle, which include methionine and folate metabolism and protein, DNA, and RNA synthesis. Carbon 130-136 methylenetetrahydrofolate reductase Homo sapiens 4-44 34960114-1 2021 The 5-10-methylenetetrahydrofolate reductase (MTHFR) enzyme is vital for cellular homeostasis due to its key functions in the one-carbon cycle, which include methionine and folate metabolism and protein, DNA, and RNA synthesis. Carbon 130-136 methylenetetrahydrofolate reductase Homo sapiens 46-51 34960563-7 2021 Finally, glucose was determined in real samples of white and red wines by using the so-obtained GOX-PANI-AuNPs/Sonogel-Carbon biosensor, providing outstanding recoveries (99.54%). Carbon 119-125 hydroxyacid oxidase 1 Homo sapiens 96-99 34115435-3 2021 In this paper, the NiP 2 nanoparticles encapsulated in three-dimensional graphene (NiP 2 @rGO) were obtained from the flower-like sphericalalpha-Ni(OH) 2 by phosphating and carbon encapsulation processes. Carbon 173-179 BCL2 interacting protein 2 Homo sapiens 19-24 34794569-0 2021 Sandwich-type electrochemical aptasensor based on hollow mesoporous carbon spheres loaded with porous dendritic Pd@Pt nanoparticles as signal amplifier for ultrasensitive detection of cardiac troponin I. Carbon 68-74 troponin I3, cardiac type Homo sapiens 184-202 15857747-2 2005 The presence of a carbon-25 hydroxyl group is necessary for optimizing binding to the VDR. Carbon 18-24 vitamin D receptor Homo sapiens 86-89 15624917-3 2005 The common 1,2-anti-2,3-syn stereotriad found in each of three subunits, aldehyde 9 (C(1)-C(5)), ester 40 (C(9)-C(16)), and aldehyde 13 (C(17)-C(24)), was established via a boron-mediated aldol reaction of ethyl ketone 15 and formaldehyde, followed by hydroxyl-directed reduction to give 1,3-diol 14. Carbon 85-86 synemin Homo sapiens 24-27 15624931-5 2005 The effect on enantioselectivity of the carbon chain length of the R group located (1) on the C-3 substituent of 4a-d, 6a-d, and 7a-d or (2) at C-5 in 8a-d and 9a-g was studied in detail. Carbon 40-46 complement C3 Homo sapiens 94-97 34115435-3 2021 In this paper, the NiP 2 nanoparticles encapsulated in three-dimensional graphene (NiP 2 @rGO) were obtained from the flower-like sphericalalpha-Ni(OH) 2 by phosphating and carbon encapsulation processes. Carbon 173-179 BCL2 interacting protein 2 Homo sapiens 83-88 15624982-3 2005 Complete selectivity for C-9 hydroxylation was restored upon acylation of the C-26 secondary alcohol. Carbon 0-1 complement C9 Homo sapiens 25-28 34287896-1 2021 In this experiment, we designed an electrochemical sensor using penicillinase (Pen X)-rhombus porous carbon (RPC) as the detection element and hematoxylin as the indicator to detect low concentrations of penicillin sodium (Pen G). Carbon 101-107 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 79-82 34817495-3 2021 Both the CF2 and CF moieties are saturated carbons and none of the R groups (R, R1, or R2) can be hydrogen". Carbon 43-50 ATPase H+ transporting accessory protein 1 Homo sapiens 9-12 34911952-4 2021 In its anionic state, the carbon impurity is computed to have a magnetic moment of 1 muB resulting from an unpaired electron populating a spin-polarized in-gap orbital. Carbon 26-32 spindlin 1 Homo sapiens 138-142 34252894-6 2021 Microdosimetric spectra and frequency-, dose-, and saturation-corrected dose-mean lineal energy (yF,yD,y*) were calculated using the Monte Carlo toolkit Geant4 for five monoenergetic and three SOBP carbon beams in water at every millimeter along the central beam axis. Carbon 198-204 sine oculis binding protein homolog Homo sapiens 193-197 34893905-5 2022 BLZ8 regulated the expression of genes likely involved in the carbon-concentrating mechanism (CCM): HIGH-LIGHT ACTIVATED 3 (HLA3), CARBONIC ANHYDRASE 7 (CAH7), and CARBONIC ANHYDRASE 8 (CAH8). Carbon 62-68 uncharacterized protein Chlamydomonas reinhardtii 131-151 34893905-5 2022 BLZ8 regulated the expression of genes likely involved in the carbon-concentrating mechanism (CCM): HIGH-LIGHT ACTIVATED 3 (HLA3), CARBONIC ANHYDRASE 7 (CAH7), and CARBONIC ANHYDRASE 8 (CAH8). Carbon 62-68 uncharacterized protein Chlamydomonas reinhardtii 153-157 34882718-5 2021 We further demonstrated that activation of TLR3 (mediated by eRNA) by AH exposure in mice induced cTrop-T release and Poly I:C (TLR3 agonist) also induced cTrop-T release, but the pre-treatment of TLR3 immuno-neutralizing antibody or silencing of Tlr3 gene or RNaseA treatment two hrs before AH exposure, significantly abrogated AH-induced Caspase 3 activity as well as cTrop-T release. Carbon 125-126 caspase 3 Mus musculus 340-349 15574355-11 2005 In addition to the C-24 oxidation pathway, human CYP24A1 catalyzed also C-23 oxidation pathway to produce 1alpha,25(OH)2D3-26,23-lactone. Carbon 19-20 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 49-56 15634132-0 2004 A density functional study on nitrogen-doped carbon clusters CnN3- (n=1-8). Carbon 45-51 calponin 3 Homo sapiens 61-65 15634132-6 2004 The CnN3- (n=1-8) with an even number of carbon atoms are more stable than those with odd numbers, matching the peak pattern observed in laser-induced mass spectra of CnN3-. Carbon 41-47 calponin 3 Homo sapiens 4-8 34591076-4 2021 Here, we show that transgenic expression of GFP-Gpc4 in the endoderm of gpc4 mutants rescued C&E defects in all germ layers. Carbon 93-94 glypican 4 Danio rerio 48-52 34591076-4 2021 Here, we show that transgenic expression of GFP-Gpc4 in the endoderm of gpc4 mutants rescued C&E defects in all germ layers. Carbon 93-94 glypican 4 Danio rerio 72-76 34712839-4 2021 More specifically, we targeted dCas9-VPR toward binding sites of Gcr1-Gcr2 and Tye7 present in several promoters of genes encoding enzymes engaged in the central carbon metabolism. Carbon 162-168 transcription regulator GCR1 Saccharomyces cerevisiae S288C 65-69 34591076-8 2021 Thus, GFP-Gpc4-labeled protrusions that emanated from endodermal cells transported Wnt5b and Wnt11f2 to other germ layers, rescuing the C&E defects caused by a gpc4 deficiency. Carbon 136-137 glypican 4 Danio rerio 10-14 34893855-10 2022 Prenatal Poly I:C exposure decreased expression of GABAA receptor subunits Gabrb3 in the PFC, and Gabrb1 and dopamine D2 (Drd2) in the hippocampus, but increased NMDA receptor subunit Grin2a in the PFC, 5-HT2A in the hippocampus, and Gabrb3 and Drd2 in the NAc. Carbon 16-17 gamma-aminobutyric acid type A receptor subunit beta1 Rattus norvegicus 98-104 34368567-0 2021 Preparation of Activated Carbon Doped with Graphene Oxide Porous Materials and Their High Gas Adsorption Performance. Carbon 25-31 gastrin Homo sapiens 90-93 34884879-8 2021 Furthermore, DMR-related genes were enriched in metabolism pathways such as carbon metabolism (serine hydroxymethyltransferase 2 (Shmt2), acyl-Coenzyme A dehydrogenase medium chain (Acadm)), arginine and proline metabolism (spermine synthase (Sms), proline dehydrogenase (Prodh2)) and purine metabolism (phosphoribosyl pyrophosphate synthetase 2 (Prps2)). Carbon 76-82 serine hydroxymethyltransferase 2 (mitochondrial) Mus musculus 95-128 34899719-9 2021 Treatment with IC87114 or transfection with siRNA targeting PI3K p110delta enhanced poly I:C-induced gene and protein expression of PD-L2, whereas IC87114 suppressed poly I:C-induced PD-L1. Carbon 91-92 programmed cell death 1 ligand 2 Homo sapiens 132-137 34899719-11 2021 Transfection with siIRF3 counteracted the enhancement of poly I:C-induced PD-L2 by IC87114, whereas IC87114 suppressed poly I:C-induced PD-L1 regardless of transfection with siNC or siIRF3. Carbon 64-65 programmed cell death 1 ligand 2 Homo sapiens 74-79 15337744-4 2004 Therefore, a ligand of a size equivalent to more than approximately 4 carbon atoms could only bind in the LBP, if ERRalpha would undergo a major conformational change (in particular the ligand would displace H12 from its agonist position). Carbon 70-76 lipopolysaccharide binding protein Homo sapiens 106-109 15537939-5 2004 Treating an aqueous RDX solution of 2.8 mg L(-1) with 20000 mg KMnO(4) L(-1) decreased RDX to 0.1 mg L(-1) within 11 d while cumulative mineralization proceeded for 14 d until 87% of the labeled carbon was trapped as (14)CO(2). Carbon 195-201 radixin Homo sapiens 20-23 34368567-1 2021 It is still a great challenge to develop a new porous carbon adsorbent with excellent separation performance and to recover low-concentration CH4 in coal mine gas. Carbon 54-60 gastrin Homo sapiens 159-162 34739026-3 2021 We focus on the recently reported encapsulation of Fe(II) spin-crossover complexes in single-walled carbon nanotubes, with new measurements that support the theoretical findings. Carbon 100-106 spindlin 1 Homo sapiens 58-62 34240869-3 2021 In every case, the torsional angle (tau) between the heteroatoms about the carbon-carbon bond connecting the two rings is at or near 180 for the global minimum and 0 for the local minimum, referred to as anti and syn conformations, respectively. Carbon 75-81 microtubule associated protein tau Homo sapiens 36-39 34767170-3 2022 The results show that ZSG efficiency allocation can significantly improve the carbon emission efficiency of inefficient provinces, and the carbon emissions of inefficient provinces after allocation reach the efficiency frontier. Carbon 78-84 POZ/BTB and AT hook containing zinc finger 1 Homo sapiens 22-25 34767170-3 2022 The results show that ZSG efficiency allocation can significantly improve the carbon emission efficiency of inefficient provinces, and the carbon emissions of inefficient provinces after allocation reach the efficiency frontier. Carbon 139-145 POZ/BTB and AT hook containing zinc finger 1 Homo sapiens 22-25 34767170-8 2022 In order to alleviate the huge pressure on the emission reduction of provinces with low actual carbon emission efficiency under the ZSG efficiency allocation mode, the Chinese government can gradually increase the weight of ZSG efficiency allocation results, and finally adopt a complete ZSG efficiency allocation scheme in the carbon peak year to realize the transformation of low-carbon economy. Carbon 95-101 POZ/BTB and AT hook containing zinc finger 1 Homo sapiens 132-135 15358094-2 2004 The ratio between C-23 and C-24 oxidation pathways in human CYP24A1-dependent metabolism of (1alpha,3alpha) and (1beta,3alpha) was 1:1, although the ratio for (1alpha,3beta) and (1beta,3beta) was 1:4. Carbon 18-19 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 60-67 15297675-3 2004 We sequenced three candidate genes (ABCA1, APOA1, and LCAT) that cause Mendelian forms of low HDL-C levels in individuals from a population-based study. Carbon 97-99 ATP binding cassette subfamily A member 1 Homo sapiens 36-41 34767170-8 2022 In order to alleviate the huge pressure on the emission reduction of provinces with low actual carbon emission efficiency under the ZSG efficiency allocation mode, the Chinese government can gradually increase the weight of ZSG efficiency allocation results, and finally adopt a complete ZSG efficiency allocation scheme in the carbon peak year to realize the transformation of low-carbon economy. Carbon 95-101 POZ/BTB and AT hook containing zinc finger 1 Homo sapiens 224-227 34767170-8 2022 In order to alleviate the huge pressure on the emission reduction of provinces with low actual carbon emission efficiency under the ZSG efficiency allocation mode, the Chinese government can gradually increase the weight of ZSG efficiency allocation results, and finally adopt a complete ZSG efficiency allocation scheme in the carbon peak year to realize the transformation of low-carbon economy. Carbon 382-388 POZ/BTB and AT hook containing zinc finger 1 Homo sapiens 132-135 34240869-3 2021 In every case, the torsional angle (tau) between the heteroatoms about the carbon-carbon bond connecting the two rings is at or near 180 for the global minimum and 0 for the local minimum, referred to as anti and syn conformations, respectively. Carbon 82-88 microtubule associated protein tau Homo sapiens 36-39 34767170-8 2022 In order to alleviate the huge pressure on the emission reduction of provinces with low actual carbon emission efficiency under the ZSG efficiency allocation mode, the Chinese government can gradually increase the weight of ZSG efficiency allocation results, and finally adopt a complete ZSG efficiency allocation scheme in the carbon peak year to realize the transformation of low-carbon economy. Carbon 382-388 POZ/BTB and AT hook containing zinc finger 1 Homo sapiens 288-291 15377091-1 2004 Hot- and cold-dose spots at a shallow depth in a target are formed by carbon ions passing through the bolus with sharp gradients. Carbon 70-76 alcohol dehydrogenase iron containing 1 Homo sapiens 0-3 34235920-1 2021 The carbon-coated LiMn0.5Fe0.5PO4@Li0.33La0.56TiO3 nanorod composites (denoted as C/LMFP@LLTO) have been successfully obtained according to a common hydrothermal synthesis following a post-calcination treatment. Carbon 4-10 steroid sulfatase Homo sapiens 79-83 34803996-0 2021 Regulation of ytfK by cAMP-CRP Contributes to SpoT-Dependent Accumulation of (p)ppGpp in Response to Carbon Starvation YtfK Responds to Glucose Exhaustion. Carbon 101-107 catabolite gene activator protein Escherichia coli 27-30 34693715-5 2021 On the contrary, cage B-H activation is very challenging since the 10 B-H bonds on o-carborane are very similar, and how to achieve the desired transformation at specific boron vertex is a long-standing issue.As carbon is considered more electronegative than boron, this property results in different vertex charges on the o-carborane cage, which follow the order B(3,6)-H << B(4,5,7,11)-H < B(8,10)-H < B(9,12)-H. We thought that this difference may trigger the favorite interaction of a proper transition metal complex with a specific B-H bond of carborane, which could be utilized to solve the selectivity issue. Carbon 212-218 bleomycin hydrolase Homo sapiens 22-25 34693715-5 2021 On the contrary, cage B-H activation is very challenging since the 10 B-H bonds on o-carborane are very similar, and how to achieve the desired transformation at specific boron vertex is a long-standing issue.As carbon is considered more electronegative than boron, this property results in different vertex charges on the o-carborane cage, which follow the order B(3,6)-H << B(4,5,7,11)-H < B(8,10)-H < B(9,12)-H. We thought that this difference may trigger the favorite interaction of a proper transition metal complex with a specific B-H bond of carborane, which could be utilized to solve the selectivity issue. Carbon 212-218 bleomycin hydrolase Homo sapiens 70-73 34693715-5 2021 On the contrary, cage B-H activation is very challenging since the 10 B-H bonds on o-carborane are very similar, and how to achieve the desired transformation at specific boron vertex is a long-standing issue.As carbon is considered more electronegative than boron, this property results in different vertex charges on the o-carborane cage, which follow the order B(3,6)-H << B(4,5,7,11)-H < B(8,10)-H < B(9,12)-H. We thought that this difference may trigger the favorite interaction of a proper transition metal complex with a specific B-H bond of carborane, which could be utilized to solve the selectivity issue. Carbon 212-218 bleomycin hydrolase Homo sapiens 537-540 15169766-9 2004 Phosphatidylglycerol is elevated in crd1 Delta mutant cells when grown in the presence of fermentable and non-fermentable carbon sources, although the extent of the increase is higher in nonfermentable medium. Carbon 122-128 cardiolipin synthase Saccharomyces cerevisiae S288C 36-40 34185502-0 2021 Facile Formation of a LiF-Carbon Layer as an Artificial Cathodic Electrolyte Interphase through Encapsulation of a Cathode with Carbon Monofluoride. Carbon 26-32 LIF interleukin 6 family cytokine Homo sapiens 22-25 34302797-2 2021 The first five carbon atoms of the sphingoid LCB, herein defined as the "sphingoid motif", are largely responsible for the unique chemical and biophysical properties of sphingolipids since they can undergo a relatively large number (compared to other lipid species) of molecular interactions with other membrane lipids, via hydrogen-bonding, charge-pairing, hydrophobic and van der Waals interactions. Carbon 15-21 clathrin light chain B Homo sapiens 45-48 34242339-2 2021 There is strong scientific consensus about the amount of sea-level rise to 2050 (0.24-0.32 m) and a range of projections to 2100, which vary depending on the approach used and the mitigation measures taken to reduce carbon emissions. Carbon 216-222 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 57-60 34144470-3 2021 The selected peptide (from dengue 1 NS1) was synthesized and employed as a template in the electropolymerization of polyaminophenol-imprinted films on the surface of carbon screen-printed electrodes. Carbon 166-172 influenza virus NS1A binding protein Homo sapiens 36-39 15248181-6 2004 Insertion of an OCHF(2) group in position 2 of the 4-phenylsubstituent and propoxyethylgroup R in ester moieties in positions 3 and 5 of the DHP structure, as well as an increase in the number of carbon atoms in the ester moiety, significantly modified the properties of the compound. Carbon 196-202 dihydropyrimidinase Rattus norvegicus 141-144 15181635-0 2004 Acceleration of carbon-13 spin-lattice relaxation times in amino acids by electrolytes. Carbon 16-22 spindlin 1 Homo sapiens 26-30 34224011-0 2021 Removal of metallic trace elements (Pb2+, Cd2+, Cu2+, and Ni2+) from aqueous solution by adsorption onto cerium oxide modified activated carbon. Carbon 137-143 CD2 molecule Homo sapiens 42-45 15181635-1 2004 Measurements of the enhancement, by various electrolytes, of the spin-lattice relaxation time of carbon-13 at different locations in a number of amino acids are reported. Carbon 97-103 spindlin 1 Homo sapiens 65-69 15181635-2 2004 Spin-lattice relaxation times T1 of all the carbons in amino acids generally tend to decrease with increase in the concentration of electrolytes, the largest effects often being observed for the charged carboxylate groups of the amino acids. Carbon 44-51 spindlin 1 Homo sapiens 0-4 15181635-3 2004 Carboxylic carbons in amino acids are the sensitive "acceptor" of the 13C spin-lattice relaxation accelerating effects offered by electrolytes, and the 13C spin-lattice relaxation accelerating ability of electrolytes decreases in the order Mg(ClO4)2 > MgCl2 > CaCl2 > NaCl > KCl > LiClO4 > NaOH. Carbon 11-18 spindlin 1 Homo sapiens 74-78 15181635-3 2004 Carboxylic carbons in amino acids are the sensitive "acceptor" of the 13C spin-lattice relaxation accelerating effects offered by electrolytes, and the 13C spin-lattice relaxation accelerating ability of electrolytes decreases in the order Mg(ClO4)2 > MgCl2 > CaCl2 > NaCl > KCl > LiClO4 > NaOH. Carbon 11-18 spindlin 1 Homo sapiens 156-160 34252429-10 2021 This study reveals efficient toxic Cr6+ removal from effluent using magnetite carbon nanocomposites which extends their application in waste water treatment. Carbon 78-84 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 35-38 34224011-1 2021 The equilibrium and kinetic studies of removal of Pb2+, Cd2+, Ni2+, and Cu2+ metal ions were carried out using activated carbon prepared from palm kernel shell and doped with CeO2 (Ce/AC). Carbon 121-127 CD2 molecule Homo sapiens 56-59 34718977-3 2022 Considering the mandate of Kyoto Protocol, this work investigates the individual and interactive impacts of renewable energy, economic growth, government effectiveness, and foreign investment towards carbon emissions in selected South Asian countries of India, Pakistan, Sri Lanka, and Bangladesh. Carbon 200-206 sorcin Homo sapiens 271-274 34117841-2 2021 Herein, the Cr-doped CoP nanorod arrays on carbon cloth (Cr-CoP-NR/CC) is reported as high performance HER catalysts with overpotentials of 38 and 209 mV at the HER current densities of 10 and 500 mA cm-2 , respectively, outperforming the performance of the commercial Pt/C at high current density. Carbon 43-49 caspase recruitment domain family member 16 Homo sapiens 21-24 34769188-3 2021 One of the important mediators in energy production and interconversion of carbons in the cell is Delta1-pyrroline-5-carboxylate (P5C)-the physiological intracellular intermediate of the interconversion of proline, ornithine, and glutamate. Carbon 75-82 pyrroline-5-carboxylate reductase 1 Homo sapiens 104-128 34769188-3 2021 One of the important mediators in energy production and interconversion of carbons in the cell is Delta1-pyrroline-5-carboxylate (P5C)-the physiological intracellular intermediate of the interconversion of proline, ornithine, and glutamate. Carbon 75-82 pyrroline-5-carboxylate reductase 1 Homo sapiens 130-133 15176825-7 2004 The reduction of the C-S bond in adducts syn-(R,S) with Na/Hg, followed by treatment of the resulting products in aqueous acid media, led to enantioenriched beta-benzyl-gamma-hydroxymethyl-gamma-butyrolactones. Carbon 21-22 synemin Homo sapiens 41-44 34117841-2 2021 Herein, the Cr-doped CoP nanorod arrays on carbon cloth (Cr-CoP-NR/CC) is reported as high performance HER catalysts with overpotentials of 38 and 209 mV at the HER current densities of 10 and 500 mA cm-2 , respectively, outperforming the performance of the commercial Pt/C at high current density. Carbon 43-49 caspase recruitment domain family member 16 Homo sapiens 60-63 34183691-1 2021 Present work comprehensively investigated the electrochemical response of Nickel-2 Aminoterephthalic acid Metal-Organic Framework (NiNH2BDC) and its reduced graphitic carbon (rGO) based hybrids for methanol (CH3OH) oxidation reaction (MOR) in an alkaline environment. Carbon 167-173 opioid receptor mu 1 Homo sapiens 235-238 15150239-2 2004 The results reveal that many operons encoding enzymes of central carbon metabolic pathways (e.g., Krebs cycle enzymes), as well as transporters and enzymes that initiate carbon metabolism, are subject to direct Crp-mediated catabolite repression. Carbon 65-71 catabolite gene activator protein Escherichia coli 211-214 34666750-11 2021 Modulation of cAMP levels had no impact on LABA/GCS modulation of Poly I:C-induced CXCL10/IP-10 or CCL5/RANTES. Carbon 73-74 C-X-C motif chemokine ligand 10 Homo sapiens 83-89 34666750-11 2021 Modulation of cAMP levels had no impact on LABA/GCS modulation of Poly I:C-induced CXCL10/IP-10 or CCL5/RANTES. Carbon 73-74 C-X-C motif chemokine ligand 10 Homo sapiens 90-95 15150239-2 2004 The results reveal that many operons encoding enzymes of central carbon metabolic pathways (e.g., Krebs cycle enzymes), as well as transporters and enzymes that initiate carbon metabolism, are subject to direct Crp-mediated catabolite repression. Carbon 170-176 catabolite gene activator protein Escherichia coli 211-214 34633574-2 2021 Core-level spectra demonstrate prevalence of sp2 hybridization of carbon atoms in CNF with a trace amount of carbon-oxygen bonds. Carbon 66-72 NPHS1 adhesion molecule, nephrin Homo sapiens 82-85 34105352-0 2021 Local Structures of Soft Carbon and Electrochemical Performance of Potassium-Ion Batteries. Carbon 25-31 POC1 centriolar protein A Homo sapiens 20-24 34626114-8 2022 Expression of AMPK and SIRT1 was reduced in gut of 6-month-old fish with poly I:C-treatment, and feeding metformin reversed these declines. Carbon 80-81 sirtuin 1 Homo sapiens 23-28 34626114-9 2022 Taken together, the present study suggested that poly I:C-injection led to aging-like phenomena in gut and metformin activated AMPK and SIRT1 to reduce NF-kappaB mediated inflammation and resist oxidative stress via enhanced expression of FoxO3a and PGC-1alpha, and finally delayed gut aging in vertebrates. Carbon 56-57 sirtuin 1 Homo sapiens 136-141 15056007-6 2004 Moreover, aminopyrrolidine derivatives at the C-7 position showed more potent cytotoxic activity than other amines or carbon derivatives. Carbon 118-124 complement C7 Homo sapiens 46-49 34105352-3 2021 Because soft carbon materials are cheap, abundant, and safe, extensive feasible research studies have indicated that they could become promising anode materials for PIBs. Carbon 13-19 POC1 centriolar protein A Homo sapiens 8-12 34641573-6 2021 The terminal carbon atom was the reactive site for the first C-H bond activation of PtC3+, which was beneficial to generate PtC3H+/CH3. Carbon 13-19 nuclear receptor coactivator 4 Homo sapiens 84-88 34105352-5 2021 Here, a series of soft carbon pyrolyzed from 900 to 2900 C were systematically and quantitatively characterized by combining Raman spectroscopy, near-edge X-ray absorption fine structure (NEXAFS) spectroscopy, X-ray pair distribution function analysis, and advanced evaluation of wide-angle X-ray scattering data. Carbon 23-29 POC1 centriolar protein A Homo sapiens 18-22 15186603-6 2004 Also, some new BN analogs containing a 6-carbon linker have been prepared and labeled with Rhenium-188, resulting in positive in vitro binding to prostate cancer cells. Carbon 41-47 gastrin releasing peptide Homo sapiens 15-17 34105352-6 2021 All these characterizations reveal structural details of soft carbon with increasing pyrolysis temperature. Carbon 62-68 POC1 centriolar protein A Homo sapiens 57-61 34533312-1 2021 An atom-economic N-to-C-directed solid-phase peptide synthesis is reported that uses benzyl (Bn) or (benzhydryl-carbamoyl)-methyl (BcM) esters of amino acids as the building blocks, which facilitate efficient hydrazinolysis, convenient conversion to acyl azide, and robust amidation with the next amino acid ester. Carbon 22-23 TNF receptor superfamily member 17 Homo sapiens 131-134 34105352-7 2021 Our results show that the potassium storage behavior, especially the potential plateau is closely correlated to non-uniformity in interlayer distance and defect concentration in soft carbon, which is further confirmed by reverse Monte Carlo (RMC) modeling and density functional theory calculation. Carbon 183-189 POC1 centriolar protein A Homo sapiens 178-182 14746449-2 2004 The C13-C21 fragment was prepared from two simple starting materials that were joined in a catalytic alkyne-epoxide fragment coupling operation, whereas an intramolecular aldehyde-alkyne reductive coupling simultaneously formed the final carbon-carbon bond of the macrocycle and established the C13 carbinol configuration with complete selectivity in the desired fashion. Carbon 238-244 homeobox C13 Homo sapiens 4-7 34105352-8 2021 On the basis of these results, optimizing strategies are discussed to design an advanced soft carbon anode. Carbon 94-100 POC1 centriolar protein A Homo sapiens 89-93 14746449-2 2004 The C13-C21 fragment was prepared from two simple starting materials that were joined in a catalytic alkyne-epoxide fragment coupling operation, whereas an intramolecular aldehyde-alkyne reductive coupling simultaneously formed the final carbon-carbon bond of the macrocycle and established the C13 carbinol configuration with complete selectivity in the desired fashion. Carbon 238-244 homeobox C13 Homo sapiens 295-298 14746449-2 2004 The C13-C21 fragment was prepared from two simple starting materials that were joined in a catalytic alkyne-epoxide fragment coupling operation, whereas an intramolecular aldehyde-alkyne reductive coupling simultaneously formed the final carbon-carbon bond of the macrocycle and established the C13 carbinol configuration with complete selectivity in the desired fashion. Carbon 245-251 homeobox C13 Homo sapiens 4-7 34105352-9 2021 This work provides significant insights into the structure engineering of soft carbon for high-performance rechargeable PIBs. Carbon 79-85 POC1 centriolar protein A Homo sapiens 74-78 34418597-6 2021 In a gain of function approach, we overexpressed phosphoenolpyruvate carboxykinase 2 (PCK2), which can drive carbon from the Krebs cycle to the glycolytic intermediate pool, and found that PCK2 augments 4F-mediated cell cycle entry. Carbon 109-115 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 49-84 34418597-6 2021 In a gain of function approach, we overexpressed phosphoenolpyruvate carboxykinase 2 (PCK2), which can drive carbon from the Krebs cycle to the glycolytic intermediate pool, and found that PCK2 augments 4F-mediated cell cycle entry. Carbon 109-115 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 86-90 34204240-0 2021 Reinforced Concrete Slabs Strengthened with Lap-Spliced Carbon TRC System. Carbon 56-62 LAP Homo sapiens 44-47 34061318-2 2021 CH25H catalyzes cholesterol to produce 25-hydroxycholesterol (25HC) by adding a second hydroxyl to the 25th carbon atom of cholesterol. Carbon 108-114 cholesterol 25-hydroxylase Homo sapiens 0-5 14711309-8 2004 The pharmacophores for gammadelta T cell activation and FPPS inhibition both consisted of two negative ionizable groups, a positive charge feature and an endocyclic carbon feature, all having very similar spatial dispositions. Carbon 165-171 farnesyl diphosphate synthase Homo sapiens 56-60 34447239-14 2021 The administration of rh-lumican to poly I:C-stimulated HLMs reduced the mRNA levels of CCL2, CCL5, and CXCL10. Carbon 43-44 C-C motif chemokine ligand 2 Homo sapiens 88-92 15218538-9 2004 The reactions that remove homocysteine are very sensitive to B vitamin status as both the transsulfuration enzymes contain pyridoxal phosphate, while methionine synthase contains cobalamin and receives its methyl group from the folic acid one-carbon pool. Carbon 243-249 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 150-169 34528380-8 2022 These syn-glacial carbonates highlight a gap in our understanding of continental weathering-and therefore, the carbon cycle-during snowball Earth. Carbon 111-117 synemin Homo sapiens 6-9 34927909-2 2021 Herein, a novel gas-phase migration strategy is developed for the scale synthesis of atomically dispersed Mn and N codoped carbon materials (g-SA-Mn) as highly effective ORR catalysts. Carbon 123-129 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 16-19 34482874-0 2021 Simultaneous sensing gamma-glutamyl transpeptidase and alkaline phosphatase by robust dual-emission carbon dots. Carbon 100-106 inactive glutathione hydrolase 2 Homo sapiens 21-50 34196706-5 2021 Moreover, we showed that the downstream signaling, e.g. STAT1 phosphorylation and IRF1 expression, was upregulated to a greater extent after high LET carbon-ion irradiation than X-rays, and that IRF1 upregulation was also ATR dependent. Carbon 150-156 signal transducer and activator of transcription 1 Homo sapiens 56-61 15143799-8 2004 The latter descriptor was found to be an important factor in explaining the experimentally observed selectivity towards the methylation of the C-4", C-6, C-11 and C-12 anions. Carbon 143-144 aldo-keto reductase family 1 member C4 Homo sapiens 154-158 34518040-1 2022 Methylthioadenosine phosphorylase (MTAP) is a rate-limiting enzyme in the methionine salvage pathway, which recycles one carbon unit that is lost during polyamine synthesis back into the methionine cycle. Carbon 121-127 methylthioadenosine phosphorylase Homo sapiens 0-33 34070770-3 2021 To address this issue, we designed and synthesized hollow CoP/FeP4 heterostructural nanorods interwoven by carbon nanotubes (CoP/FeP4@CNT) via a hydrothermal reaction and a phosphorization process. Carbon 107-113 caspase recruitment domain family member 16 Homo sapiens 58-61 34518040-1 2022 Methylthioadenosine phosphorylase (MTAP) is a rate-limiting enzyme in the methionine salvage pathway, which recycles one carbon unit that is lost during polyamine synthesis back into the methionine cycle. Carbon 121-127 methylthioadenosine phosphorylase Homo sapiens 35-39 34572549-3 2021 They hydrolyse glucosidic bonds of alpha-1,4"-d-glucans and transfer the glucan portion with the newly available anomeric carbon to the 4"-position of an alpha-1,4"-d-glucan acceptor. Carbon 122-128 immunoglobulin kappa variable 2D-30 Homo sapiens 35-42 34572549-3 2021 They hydrolyse glucosidic bonds of alpha-1,4"-d-glucans and transfer the glucan portion with the newly available anomeric carbon to the 4"-position of an alpha-1,4"-d-glucan acceptor. Carbon 122-128 immunoglobulin kappa variable 2D-30 Homo sapiens 154-161 14636062-7 2003 In the second experiment, we found that hE149A compared with hLCAT demonstrated higher activity with PC species containing 20-carbon, but not 18-carbon, sn-2 fatty acyl chains. Carbon 126-132 lecithin-cholesterol acyltransferase Homo sapiens 61-66 14636062-7 2003 In the second experiment, we found that hE149A compared with hLCAT demonstrated higher activity with PC species containing 20-carbon, but not 18-carbon, sn-2 fatty acyl chains. Carbon 145-151 lecithin-cholesterol acyltransferase Homo sapiens 61-66 34070770-3 2021 To address this issue, we designed and synthesized hollow CoP/FeP4 heterostructural nanorods interwoven by carbon nanotubes (CoP/FeP4@CNT) via a hydrothermal reaction and a phosphorization process. Carbon 107-113 caspase recruitment domain family member 16 Homo sapiens 125-128 14654433-4 2003 Northern blot analysis of ATF1 and its closely related homologue, Lg-ATF1, showed that these genes were rapidly induced by the addition of glucose to anaerobically grown carbon-starved cells. Carbon 170-176 alcohol O-acetyltransferase Saccharomyces cerevisiae S288C 26-30 34115276-1 2021 A facile and green strategy was carried out for the preparation of fluorescent carbon nanoparticles (CNp) using non-toxic circassian seeds as carbon precursor (CNp, named ACNp). Carbon 79-85 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor Homo sapiens 171-175 34115276-1 2021 A facile and green strategy was carried out for the preparation of fluorescent carbon nanoparticles (CNp) using non-toxic circassian seeds as carbon precursor (CNp, named ACNp). Carbon 142-148 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor Homo sapiens 171-175 14654433-4 2003 Northern blot analysis of ATF1 and its closely related homologue, Lg-ATF1, showed that these genes were rapidly induced by the addition of glucose to anaerobically grown carbon-starved cells. Carbon 170-176 alcohol O-acetyltransferase Saccharomyces cerevisiae S288C 69-73 34467289-7 2021 Using a commercially available benchmark IrO2 catalyst deposited on a carbon gas diffusion layer (GDL), it is shown that key parameters such as the OER mass activity, the activation energy, and even reasonable estimates of the exchange current density can be extracted in a realistic range of catalyst loadings for PEMWEs. Carbon 70-76 gastrin Homo sapiens 77-80 34502203-1 2021 The present paper developed a new enzymatic biosensor whose support is a screen-printed electrode based on carbon nanofibers modified with cobalt phthalocyanine and laccase (CNF-CoPc-Lac/SPE) to determine the p-coumaric acid (PCA) content by cyclic voltammetry and square wave voltammetry. Carbon 107-113 NPHS1 adhesion molecule, nephrin Homo sapiens 174-177 35605852-0 2022 Negative impacts of sea-level rise on soil microbial involvement in carbon metabolism. Carbon 68-74 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 20-23 34391473-8 2021 Stimulation with the TLR2, 3 and 4 agonists Pam3CSK4, Poly I:C and LPS, respectively, induced the pro-inflammatory cytokines TNF-alpha and IL-8, while the TLR5 agonist FliC only induced TNF-alpha. Carbon 61-62 C-X-C motif chemokine ligand 8 Equus caballus 139-143 34288161-2 2021 In this work, a novel Fex -1 Sex heterostructure is prepared on fungus-derived carbon matrix encapsulated by 2D Ti3 C2 Tx MXene highly conductive layers, which exhibits high specific sodium ion (Na+ ) and potassium ion (K+ ) storage capacities of 610.9 and 449.3 mAh g-1 at a current density of 0.1 A g-1 , respectively, and excellent capacity retention at high charge-discharge rates. Carbon 79-85 stabilin 1 Homo sapiens 22-28 34152457-9 2021 The anti-NS1 monoclonal antibodies were immobilized to carbon nanotubes by covalent linkage, permitting a high stability during measurements. Carbon 55-61 influenza virus NS1A binding protein Homo sapiens 9-12 14700233-1 2003 The preparation of an enzyme-dispersed carbon-nanotube (CNT) electrode, based on mixing glucose oxidase (GOx) within CNT, is described. Carbon 39-45 hydroxyacid oxidase 1 Homo sapiens 88-103 14700233-1 2003 The preparation of an enzyme-dispersed carbon-nanotube (CNT) electrode, based on mixing glucose oxidase (GOx) within CNT, is described. Carbon 39-45 hydroxyacid oxidase 1 Homo sapiens 105-108 14656028-1 2003 One-carbon metabolism is under the influence of folate, vitamin B12 and genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR 677 C --> T and 1298 A --> C), of methionine synthase (MTR 2756 C --> G), methionine synthase reductase (MTRR 66 A --> G) and transcobalamin (TCN 776 C --> G). Carbon 4-10 methylenetetrahydrofolate reductase Homo sapiens 97-132 14656028-1 2003 One-carbon metabolism is under the influence of folate, vitamin B12 and genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR 677 C --> T and 1298 A --> C), of methionine synthase (MTR 2756 C --> G), methionine synthase reductase (MTRR 66 A --> G) and transcobalamin (TCN 776 C --> G). Carbon 4-10 methylenetetrahydrofolate reductase Homo sapiens 134-139 14656028-1 2003 One-carbon metabolism is under the influence of folate, vitamin B12 and genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR 677 C --> T and 1298 A --> C), of methionine synthase (MTR 2756 C --> G), methionine synthase reductase (MTRR 66 A --> G) and transcobalamin (TCN 776 C --> G). Carbon 4-10 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 180-199 35605852-1 2022 Sea-level rise has been threatening the terrestrial ecosystem functioning of coastal islands, of which the most important component is carbon (C) cycling. Carbon 135-141 S13 erythroblastosis (avian) oncogene homolog Homo sapiens 0-3 35259619-1 2022 A novel electrochemical sensor based on the modification of carbon paste electrode with an ionic liquid (1-butyl-2,3-dimethylimidazolium tetrafluoroborate) and AuTiO2/GO composite (IL/AuTiO2/GO/CPE) was developed for rapid and sensitive determination of tartrazine by differential pulse voltammetry. Carbon 60-66 carboxypeptidase E Homo sapiens 184-197 34218391-9 2021 The expression of prdm1a was high while the expression of bcl6aa was low, and vice versa, detected in the spleen after stimulation with LPS or polyI:C. Carbon 149-150 PR domain zinc finger protein 1 Oryzias latipes 18-24 35378472-6 2022 Based on the multiple functions of nitrogen-doped carbon fibers and CeO2, Li-S batteries with NCF@CeO2 interlayers exhibit superior electrochemical performances, including a high discharge specific capacity of 1072.9 mAh g-1 at 0.2 C and a low capacity decay rate of only 0.063% per cycle after 1000 cycles. Carbon 50-56 neutrophil cytosolic factor 4 Homo sapiens 94-97 34440679-9 2021 Flagellin, PMA and poly I:C exerted proinflammatory action in certain concentrations in both 2D and 3D cultures, reflected by the increased cellular IL-6 release. Carbon 26-27 interleukin 6 Gallus gallus 149-153 34240687-2 2021 In this study, the use of carbon aerogel as a novel catalyst with high porosity(the total pore volume of 1.84 cm3g-1) and high surface area (491.7 m2/g) for improving the oxygen reduction reaction (ORR) performance was compared to that of the conventional activated carbon, employed as an air cathode catalyst in bio-electrochemical systems, with the indigenous bacterial consortium.The electrochemical studies revealed the higher power efficiency in the use of carbon aerogel (with the maximum power density and current density of a 675 mWm-2 and 33.1 mAm-2, respectively), as compared to the activated carbon (with the maximum power density and current density of 668.98 mWm-2 and 23.2 mAm-2, respectively). Carbon 26-32 adrenomedullin 2 Mus musculus 553-558 34240687-2 2021 In this study, the use of carbon aerogel as a novel catalyst with high porosity(the total pore volume of 1.84 cm3g-1) and high surface area (491.7 m2/g) for improving the oxygen reduction reaction (ORR) performance was compared to that of the conventional activated carbon, employed as an air cathode catalyst in bio-electrochemical systems, with the indigenous bacterial consortium.The electrochemical studies revealed the higher power efficiency in the use of carbon aerogel (with the maximum power density and current density of a 675 mWm-2 and 33.1 mAm-2, respectively), as compared to the activated carbon (with the maximum power density and current density of 668.98 mWm-2 and 23.2 mAm-2, respectively). Carbon 26-32 adrenomedullin 2 Mus musculus 688-693 34240687-2 2021 In this study, the use of carbon aerogel as a novel catalyst with high porosity(the total pore volume of 1.84 cm3g-1) and high surface area (491.7 m2/g) for improving the oxygen reduction reaction (ORR) performance was compared to that of the conventional activated carbon, employed as an air cathode catalyst in bio-electrochemical systems, with the indigenous bacterial consortium.The electrochemical studies revealed the higher power efficiency in the use of carbon aerogel (with the maximum power density and current density of a 675 mWm-2 and 33.1 mAm-2, respectively), as compared to the activated carbon (with the maximum power density and current density of 668.98 mWm-2 and 23.2 mAm-2, respectively). Carbon 462-468 adrenomedullin 2 Mus musculus 553-558 14521880-4 2003 When compared to the wild-type and the rpoS- strains, the hfq knock out strain showed a reduced growth rate and was unable to utilize glucose as a sole carbon source. Carbon 152-158 RNA-binding protein Hfq Pseudomonas aeruginosa PAO1 58-61 35487149-4 2022 ArsI is a non-heme ferrous iron (Fe(II))-dependent dioxygenase that catalyzes oxygen-dependent cleavage of the carbon-arsenic (C-As) bond in trivalent organoarsenicals, degrading them to inorganic As(III). Carbon 111-117 arylsulfatase family member I Homo sapiens 0-4 14551334-0 2003 Reduced expression of aconitase results in an enhanced rate of photosynthesis and marked shifts in carbon partitioning in illuminated leaves of wild species tomato. Carbon 99-105 aconitate hydratase, cytoplasmic Solanum pennellii 22-31 34240687-2 2021 In this study, the use of carbon aerogel as a novel catalyst with high porosity(the total pore volume of 1.84 cm3g-1) and high surface area (491.7 m2/g) for improving the oxygen reduction reaction (ORR) performance was compared to that of the conventional activated carbon, employed as an air cathode catalyst in bio-electrochemical systems, with the indigenous bacterial consortium.The electrochemical studies revealed the higher power efficiency in the use of carbon aerogel (with the maximum power density and current density of a 675 mWm-2 and 33.1 mAm-2, respectively), as compared to the activated carbon (with the maximum power density and current density of 668.98 mWm-2 and 23.2 mAm-2, respectively). Carbon 462-468 adrenomedullin 2 Mus musculus 688-693 34137419-3 2021 By introducing C defects, we have successfully converted the semi-conductive SiC into metallic carbon-defective silicon carbide (SiC1-x), and endowed it with the near infrared absorption property for photothermal therapy (PTT). Carbon 95-101 Fli-1 proto-oncogene, ETS transcription factor Homo sapiens 129-133 12974653-1 2003 Allenes with a nucleophilic functionality connected to the alpha-carbon atom have been shown to be versatile building blocks for the syn-thesis of gamma-butenolides, gamma-lactams, gamma-iminolactones, vinylic epoxides, 4-amino-2-alkenols, 2-amino-3-alkenols, 2,5-dihydrofurans, furans, vinylic cyclopropanes, and cyclopentenes, depending on the nature of the nucleophilic centers. Carbon 65-71 synemin Homo sapiens 133-136 34139681-0 2021 Ionic liquid-derived Fe, N, S, F multiple heteroatom-doped carbon materials for enhanced oxygen reduction reaction. Carbon 59-65 general transcription factor IIE subunit 1 Homo sapiens 21-23 34139681-2 2021 Herein, the microporous-mesoporous carbon material catalysts doped with Fe, N, S and F were synthesized through a plain one-pot pyrolysis method with ionic liquid 1-butyl-3-methyli-midazolium bis((trifluoromethyl)sulfonyl)imide ((Bmim)(TF2N)) and melamine as precursors. Carbon 35-41 general transcription factor IIE subunit 1 Homo sapiens 72-74 35636361-3 2022 This paper investigates the electrochemical determination of the mefenamic acid (MEF), with a novel carbon paste electrode modified with terbium titanate nanostructures (TTN/CPE). Carbon 100-106 carboxypeptidase E Homo sapiens 174-177 35618144-3 2022 Variability in immobilization efficacy was attributed to differences in activated carbon composition which influenced physicochemical properties of RemBind formulations and PFAS sorption. Carbon 82-88 phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) Mus musculus 174-178 34276623-4 2021 Dissimilatory Fe(III)-reducing archaea (FeRA) and Fe(II)-oxidizing archaea (FeOA) are widespread on Earth where they play crucial roles in biogeochemical cycling of not only Fe, but also carbon and sulfur. Carbon 187-193 general transcription factor IIE subunit 1 Homo sapiens 14-21 12923087-1 2003 The cyclic AMP receptor protein (CRP) activates transcription of the Escherichia coli acs gene, which encodes an acetate-scavenging enzyme required for fitness during periods of carbon starvation. Carbon 178-184 catabolite gene activator protein Escherichia coli 4-31 12923087-1 2003 The cyclic AMP receptor protein (CRP) activates transcription of the Escherichia coli acs gene, which encodes an acetate-scavenging enzyme required for fitness during periods of carbon starvation. Carbon 178-184 catabolite gene activator protein Escherichia coli 33-36 12700234-4 2003 Shm2p and Ade3p are cytoplasmic enzymes producing 5,10-methylene tetrahydrofolate in convergent pathways as the primary source for cellular one-carbon groups. Carbon 144-150 glycine hydroxymethyltransferase SHM2 Saccharomyces cerevisiae S288C 0-5 34121323-2 2021 Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), a mitochondrial enzyme of one-carbon metabolism, has been reported to be dysregulated in many cancers. Carbon 82-88 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 0-41 34121323-2 2021 Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), a mitochondrial enzyme of one-carbon metabolism, has been reported to be dysregulated in many cancers. Carbon 82-88 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 43-49 35636290-0 2022 Molten salt-induced vertical CoP/Co nanosheets array coupled with carbon for efficient water splitting. Carbon 66-72 caspase recruitment domain family member 16 Homo sapiens 29-32 14749026-12 2003 Two substituents on the left-hand carbons C-7 and C-8 of ring C were shown to be responsible for a strong sensitizing capacity. Carbon 34-41 complement component C7 Cavia porcellus 42-45 35636290-2 2022 Herein, a facile heterogeneous molten salt strategy has been proposed to fabricate CoP/Co nanosheets array that is vertically attached to a carbon matrix. Carbon 140-146 caspase recruitment domain family member 16 Homo sapiens 83-86 33715691-0 2021 The Effects of Fe Film Thickness and the H2 Annealing Time on the Spin-Capability of Carbon Nanotube Forest with Chemical Vapor Deposition Method. Carbon 85-91 spindlin 1 Homo sapiens 66-70 33715691-1 2021 The effects of as-deposited iron (Fe) film thickness and the hydrogen (H2) annealing time on the spin-capability of carbon nanotube (CNT) forest have been studied. Carbon 116-122 spindlin 1 Homo sapiens 97-101 35609787-3 2022 Interestingly, the hpm1 deletion strain is highly pleiotropic, with many extra-ribosomal phenotypes including improved growth rates in alternative carbon sources. Carbon 147-153 protein-histidine N-methyltransferase Saccharomyces cerevisiae S288C 19-23 33715691-2 2021 Both, the as-deposited Fe film thickness and the H2 annealing time significantly changed the morphology of Fe nanoparticles (NPs) after annealing process during the synthesis step of spin-capable carbon nanotube (SCNT) forest. Carbon 196-202 spindlin 1 Homo sapiens 183-187 34115630-1 2021 Degradation activity of plasma catalysis between dielectric barrier discharge (DBD) and carbon nanotubes-graphene-nickel foam (CNTs-G-Nif) has been studied in treatment of dye wastewater. Carbon 88-94 S100 calcium binding protein A9 Homo sapiens 134-137 12762671-1 2003 [reaction: see text] Metalation of a Boc-protected N-silylamine alpha to nitrogen results in migration of the silicon from nitrogen to carbon (reverse aza-Brook rearrangement), yielding an alpha-amino silane. Carbon 135-141 BOC cell adhesion associated, oncogene regulated Homo sapiens 37-40 12646567-6 2003 The generation of one-carbon units by mitochondria in nmdmc(-/-) cells is completely blocked, and the cytoplasmic folate pathways alone are insufficient for optimal purine synthesis. Carbon 22-28 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 54-59 35627566-1 2022 Brownfield regeneration (BR) is an important initiative for sustainable land development and the promotion of carbon neutrality. Carbon 110-116 chromosome 12 open reading frame 73 Homo sapiens 25-27 34071561-7 2021 Body temperature and haptoglobin concentration dropped between Day 0 and 4 in both CD and C, approaching the level of CTR. Carbon 90-91 haptoglobin Bos taurus 21-32 35562375-4 2022 Here, we use carbon isotope and PVT data from co-produced hydrocarbon gas and liquid to provide evidence for widespread migration of gas-condensate in the Montney unconventional petroleum system of western Canada. Carbon 13-19 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 70-73 34073651-7 2021 In addition, the accumulation of powdered activated carbon in O3-BAC pre-treated water on the membrane surface could be the key reason protecting the NF membrane from fouling. Carbon 52-58 neurofascin Homo sapiens 150-152 12732685-11 2003 CONCLUSION: These studies showed that radiometallated DOTA-X-BBN[7-14]NH(2) constructs with hydrocarbon spacers ranging from 5 to 8 carbon atoms are feasible candidates for further development as diagnostic and therapeutic radiopharmaceuticals for patients with GRP-positive cancers. Carbon 97-103 gastrin releasing peptide Homo sapiens 61-64 35562375-4 2022 Here, we use carbon isotope and PVT data from co-produced hydrocarbon gas and liquid to provide evidence for widespread migration of gas-condensate in the Montney unconventional petroleum system of western Canada. Carbon 13-19 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 133-136 12848296-6 2003 These results demonstrate that SC-26196 effectively inhibits the desaturation of 18- and 24-carbon PUFA and, therefore, decreases the synthesis of arachidonic acid, EPA, and DHA in human cells. Carbon 92-98 pumilio RNA binding family member 3 Homo sapiens 99-103 34928078-5 2021 Molecular-level investigations reveal that MXene exhibits a strong chemisorption mechanism for immobilizing cytokine interleukin-6 molecules, which is different from activated carbon absorbents. Carbon 176-182 TNF receptor superfamily member 8 Homo sapiens 108-116 35486896-3 2022 We have developed a series of carbon-supported novel PdHx nanosheets (PdHx NS), which displayed outstanding ORR performance in room-temperature RDE tests. Carbon 30-36 pyruvate dehydrogenase complex component X Homo sapiens 53-57 35595134-4 2022 First, we propose a methodological framework to comprehensively evaluate the operational efficiency of carbon ETMs, and use the DCC-GARCH model to analyse information exchange and interaction between domestic and international carbon ETMs. Carbon 227-233 DCC netrin 1 receptor Homo sapiens 128-131 12527758-8 2003 In these mutants, Rgt1 behaves as a constitutive repressor independent of the carbon source. Carbon 78-84 Rgt1p Saccharomyces cerevisiae S288C 18-22 12633750-8 2003 This is followed by oxygen transfer to the most electropositive carbon atoms, C-6, C-1, and C-3, with formation of 6-OHBP (and its quinones), 1-OHBP, and 3-OHBP, respectively, or the most electropositive 4,5-, 7,8-, and 9,10- double bonds, with formation of BP 4,5-, 7,8-, or 9,10-oxide. Carbon 64-70 complement C3 Rattus norvegicus 92-95 35512582-2 2022 In this work, we constructed a breath alcohol biosensor based on a hydrogel-gated graphene field-effect transistor (HGGT) with chlorella derived layered carbon nanosheets (CNs) and alcohol oxidase (AOx) embedded in the hydrogel. Carbon 153-159 acyl-CoA oxidase 1 Homo sapiens 198-201 35486896-3 2022 We have developed a series of carbon-supported novel PdHx nanosheets (PdHx NS), which displayed outstanding ORR performance in room-temperature RDE tests. Carbon 30-36 pyruvate dehydrogenase complex component X Homo sapiens 70-74 35262982-6 2022 In this study, a high-performance N,Cu-CoP/carbon cloth (CC) catalyst was synthesized to catalyze the cathodic hydrogen evolution reaction (HER) at an especially low overpotential of 64.7 mV at 10 mA cm-2 . Carbon 43-49 caspase recruitment domain family member 16 Homo sapiens 39-42 35334330-5 2022 In conclusion, we developed a sensitive screen-printed carbon electrodes based electrochemical sensor and gold nano particle based lateral flow strip assay strategy to successfully genotyping CYP2C19*2 GG, GA and AA genotype. Carbon 55-61 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 192-199 35247814-3 2022 Herein, three carbon dots (CDs1 to CDs3) decorated modified-carbon nitride (CDs1-NCN, CDs2-NCN and CDs3-NCN) were designed and fabricated, which show diverse activity of H2O2 photoproduction. Carbon 14-20 CDP-diacylglycerol synthase 2 Homo sapiens 86-90 35122815-0 2022 Enhanced sun light driven photocatalytic activity of Co doped SnO2 loaded corn cob activated carbon for methylene blue dye degradation. Carbon 93-99 metabolism of cobalamin associated B Homo sapiens 79-82 35149072-5 2022 Increasing the chlorine dose increased double bond equivalent minus oxygen values of Cl1-DBPs and decreased the double bond equivalent minus oxygen values of Cl2-DBPs, while the nominal oxidant state of carbon decreased for Cl1-DBPs and increased for Cl2-DBPs. Carbon 203-209 endogenous retrovirus group W member 5 Homo sapiens 251-254 35594015-0 2022 Experimental dosimetry of EDR2 films in scanning carbon-ion irradiation. Carbon 49-55 polyhomeotic homolog 2 Homo sapiens 26-30 35594015-1 2022 PURPOSE: To investigate the dose-sensitometric response of extended dose range (EDR2) films to scanning carbon-ion beams and to evaluate the applications of the obtained response curves to carbon-ion dose distributions. Carbon 104-110 polyhomeotic homolog 2 Homo sapiens 80-84 35594015-2 2022 METHODS: EDR2 films were irradiated by mono-energetic scanning carbon-ion beams with different doses to obtain sensitometric curves at different integrated depth doses (DDDs). Carbon 63-69 polyhomeotic homolog 2 Homo sapiens 9-13 35594015-6 2022 RESULTS: Digitizing the EDR2 film with a resolution of 0.36 (72 dpi) provided a good signal-to-noise ratio, and the sensitometric curve was linear at all DDDs of clinically relevant incident kinetic energies in the netOD range of 0.02-1.70 for carbon-ion film dosimetry. Carbon 244-250 polyhomeotic homolog 2 Homo sapiens 24-28 35594015-8 2022 CONCLUSION: The EDR2 film is a feasible tool for scanning carbon-ion beam profile measurements by directly evaluating the netOD distribution with proper digitizing resolution and netOD range. Carbon 58-64 polyhomeotic homolog 2 Homo sapiens 16-20 35594015-9 2022 By applying the conversion factors, the EDR2 film can also be employed to perform the percentage depth dose consistency checking and linear energy transfer comparison of carbon-ion lower than 307.5 MeV/u. Carbon 170-176 polyhomeotic homolog 2 Homo sapiens 40-44 12588119-7 2003 Spin densities at carbon in the C(6)H(5) and C(3)F(7) groups were estimated from the (1)H and (19)F contact shifts. Carbon 18-24 spindlin 1 Homo sapiens 0-4 12619410-0 2003 The characterisation of supported platinum nanoparticles on carbon used for enantioselective hydrogenation: a combined electrochemical-STM approach. Carbon 60-66 sulfotransferase family 1A member 3 Homo sapiens 135-138 35491397-4 2022 Especially the Cu 2+ species those were in-situ formed during the reaction played a vital role in enhancing the activity and selectivity of the proposed copper/carbon paper (Cu/CP) hybrid catalyst. Carbon 160-166 ceruloplasmin Homo sapiens 177-179 12908238-4 2003 A peculiar carbon nanostructure was generated from the template for pore expanded MCM-41. Carbon 11-17 methylmalonyl-CoA mutase Homo sapiens 82-85 35594343-3 2022 Nuclear enrichment of GSK3 significantly suppresses genes that mediate de novo serine synthesis, including PHGDH, PSAT1, PSPH, and one-carbon metabolism, including SHMT2 and MTHFD2. Carbon 135-141 serine hydroxymethyltransferase 2 Homo sapiens 164-169 35594343-3 2022 Nuclear enrichment of GSK3 significantly suppresses genes that mediate de novo serine synthesis, including PHGDH, PSAT1, PSPH, and one-carbon metabolism, including SHMT2 and MTHFD2. Carbon 135-141 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 174-180 35594343-4 2022 FRAT1 promotes nuclear exclusion of GSK3, enhances serine/one-carbon metabolism, and, as a result, confers cell vulnerability to inhibitors that target this metabolic process such as SHIN1, a specific SHMT1/2 inhibitor. Carbon 62-68 FRAT regulator of WNT signaling pathway 1 Homo sapiens 0-5 35196069-5 2022 Transcriptome-wide analysis revealed a coordinated regulation of metabolic enzymes related to one-carbon metabolism, including three methyltransferase enzymes (KMT2D, SETD1B, and ASH1L), key enzymes for both carnitine synthesis and histone modification. Carbon 98-104 lysine methyltransferase 2D Homo sapiens 160-165 35475353-2 2022 Although heteroatom doping has been developed into an effective method to modify carbon nanomaterials for various heterogeneous adsorption and catalytic oxidation systems, the active source regulated by intrinsic electron and spin structures is still obscure. Carbon 81-87 spindlin 1 Homo sapiens 226-230 12506214-5 2003 Comparison of the Sn-O, C-O and aryl C-C bond lengths with those of related compounds shows that the most important resonance forms for the Schiff base aryloxide ligand are double zwitterions, but that the uncharged resonance forms having carbonyl groups also contribute significantly. Carbon 0-1 strawberry notch homolog 2 Homo sapiens 18-27 35041951-3 2022 This study aims to reconstruct a Carbon Productivity (CP) indicator at the farm level to analyse its eventual relationship with the farm"s economic performance as measured by its Farm Net Value Added (FNVA). Carbon 33-39 ceruloplasmin Homo sapiens 54-56 15058183-2 2003 In Saccharomyces cerevisiae the plasma membrane proteins Ras1 and Ras2 are sensing the nutritional status of the environments, e.g., the abundance and quality of available carbon sources. Carbon 172-178 Ras family GTPase RAS1 Saccharomyces cerevisiae S288C 57-61 35475353-9 2022 This work established a relation between electron and spin structures for adsorption and photocatalysis, paving a new way to design modified carbon nanomaterials to control OMPs. Carbon 141-147 spindlin 1 Homo sapiens 54-58 35144170-0 2022 Molecularly imprinted polymer-based electrochemical impedimetric sensors on screen-printed carbon electrodes for the detection of trace cytokine IL-1beta. Carbon 91-97 TNF receptor superfamily member 8 Homo sapiens 136-144 35144170-1 2022 In this study, protein-imprinted sensors were electrochemically fabricated on screen-printed carbon electrodes (SPCEs) for the cytokine interleukin-1beta (IL-1beta) detection. Carbon 93-99 TNF receptor superfamily member 8 Homo sapiens 127-135 12586704-8 2003 ELO-2 cooperates with the previously reported ELO-1 in 20-carbon PUFA production, and at least one of the enzymes must function to provide normal growth and development in C. elegans. Carbon 58-64 Elongation of long chain fatty acids protein 2 Caenorhabditis elegans 0-5 35535493-2 2022 Using a genetic screen in haploid human cells, we discovered that the enantiospecific cytotoxicity of numerous terminal alkynylcarbinols, including the highly cytotoxic dialkynylcarbinols, involves a bioactivation by HSD17B11, a short-chain dehydrogenase/reductase (SDR) known to oxidize the C-17 carbinol center of androstan-3-alpha,17-beta-diol to the corresponding ketone. Carbon 292-293 hydroxysteroid 17-beta dehydrogenase 11 Homo sapiens 217-225 35499203-3 2022 Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs). Carbon 213-219 suprabasin Homo sapiens 187-191 35533487-4 2022 Herein, Sb is firstly captured by mesoporous carbon sphere (MCS) to form a composite of Sb/MCS, and then reduced graphene oxide (rGO) is adopted as an outer layer to wrap the Sb/MCS to obtain the dual-carbon confinement material (Sb/MCS@rGO). Carbon 201-207 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 178-181 35533487-4 2022 Herein, Sb is firstly captured by mesoporous carbon sphere (MCS) to form a composite of Sb/MCS, and then reduced graphene oxide (rGO) is adopted as an outer layer to wrap the Sb/MCS to obtain the dual-carbon confinement material (Sb/MCS@rGO). Carbon 201-207 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 233-236 35533487-7 2022 Benefiting from the dual-carbon confinement effects, the Sb/MCS@rGO electrode processes promising electrochemical reaction kinetics. Carbon 25-31 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 60-63 14524674-11 2003 Reductions in BOD, COD, TOC, AOX, and phenols by biological treatment increased when samples were pretreated with ozone/activated carbon. Carbon 130-136 acyl-CoA oxidase 1 Homo sapiens 29-32 35510894-0 2022 A Molten-Salt Method to Synthesize Co9 S8 Embedded, N, S Co-Doped Mesoporous Carbons from Melamine Formaldehyde Resins for Electrocatalytic Hydrogen Evolution Reactions. Carbon 77-84 phosphoserine phosphatase pseudogene 1 Homo sapiens 35-38 35499203-3 2022 Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs). Carbon 213-219 suprabasin Homo sapiens 295-299 35499203-3 2022 Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs). Carbon 244-250 suprabasin Homo sapiens 187-191 35499203-3 2022 Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs). Carbon 244-250 suprabasin Homo sapiens 295-299 35499203-3 2022 Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs). Carbon 278-284 suprabasin Homo sapiens 187-191 12518234-1 2003 PHO85 is a versatile gene in Saccharomyces cerevisiae, which is involved in metabolism of inorganic phosphate and usage of carbon source, accumulation of glycogen, regulation of protein stability and cell cycle control. Carbon 123-129 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 0-5 35477523-0 2022 TFEB-lysosome pathway activation is associated with different cell death responses to carbon quantum dots in Kupffer cells and hepatocytes. Carbon 86-92 transcription factor EB Mus musculus 0-4 35591555-1 2022 The purpose of our research was to develop a new enzymatic biosensor, GPH-MnPc-Tyr/SPE, using as a support screen-printed carbon electrode (SPE) modified with graphene, manganese phthalocyanine, and tyrosinase, with the aim of developing sensitive detection of chlorogenic acid (CGA). Carbon 122-128 gephyrin Homo sapiens 70-73 35566069-4 2022 It adopts a novel mechanism to promote SIRT1 activity by covalently bonding to the anomeric C1" carbon of the ribose ring in OAADPr. Carbon 96-102 sirtuin 1 Homo sapiens 39-44 35566069-6 2022 The longer distance between the anomeric C1" carbon of the ribose ring in OAADPr and Arg274 of SIRT1 (a conserved residue among sirtuins) than that between the anomeric C1" carbon in OAADPr and the Arg of SIRT2, SIRT3, SIRT5, and SIRT6, should be responsible for the high selectivity of CWR for SIRT1. Carbon 45-51 sirtuin 1 Homo sapiens 95-100 35566069-6 2022 The longer distance between the anomeric C1" carbon of the ribose ring in OAADPr and Arg274 of SIRT1 (a conserved residue among sirtuins) than that between the anomeric C1" carbon in OAADPr and the Arg of SIRT2, SIRT3, SIRT5, and SIRT6, should be responsible for the high selectivity of CWR for SIRT1. Carbon 173-179 sirtuin 1 Homo sapiens 95-100 12409727-10 2002 Tangential cutting of MIB-1-positive parabasal cells and inflammatory cells can erroneously be overdiagnosed as a MIB-C. Carbon 118-119 MIB E3 ubiquitin protein ligase 1 Homo sapiens 22-27 12409727-10 2002 Tangential cutting of MIB-1-positive parabasal cells and inflammatory cells can erroneously be overdiagnosed as a MIB-C. Carbon 118-119 MIB E3 ubiquitin protein ligase 1 Homo sapiens 22-25 35533478-0 2022 Confined transformation of trifunctional Co2(OH)2CO3 nanosheet assemblies into hollow porous Co@N-doped carbon spheres for efficient microwave absorption. Carbon 104-110 complement C2 Homo sapiens 41-44 12414713-0 2002 (13)C-(1)H NMR relaxation and fluorescence anisotropy decay study of tyrosine dynamics in motilin. Carbon 4-5 motilin Homo sapiens 90-97 12414713-2 2002 Motilin, a 22-residue peptide, was selectively (13)C labeled in the ring epsilon-carbons of the single tyrosine residue. Carbon 81-88 motilin Homo sapiens 0-7 35422087-1 2022 Mitochondrial serine hydroxymethyltransferase (SHMT2) catalyzes the conversion of serine to glycine and concomitantly produces one-carbon units to support cell growth and is upregulated in various cancer cells. Carbon 131-137 serine hydroxymethyltransferase 2 Homo sapiens 0-45 35422087-1 2022 Mitochondrial serine hydroxymethyltransferase (SHMT2) catalyzes the conversion of serine to glycine and concomitantly produces one-carbon units to support cell growth and is upregulated in various cancer cells. Carbon 131-137 serine hydroxymethyltransferase 2 Homo sapiens 47-52 35422087-4 2022 SHMT2 knockout decreased the pools of purine and one-carbon units and delayed cell cycle progression in a manner that was rescued by formate, demonstrating that SHMT2-mediated one-carbon units are essential for BC cell proliferation. Carbon 53-59 serine hydroxymethyltransferase 2 Homo sapiens 0-5 35422087-4 2022 SHMT2 knockout decreased the pools of purine and one-carbon units and delayed cell cycle progression in a manner that was rescued by formate, demonstrating that SHMT2-mediated one-carbon units are essential for BC cell proliferation. Carbon 53-59 serine hydroxymethyltransferase 2 Homo sapiens 161-166 35422087-4 2022 SHMT2 knockout decreased the pools of purine and one-carbon units and delayed cell cycle progression in a manner that was rescued by formate, demonstrating that SHMT2-mediated one-carbon units are essential for BC cell proliferation. Carbon 180-186 serine hydroxymethyltransferase 2 Homo sapiens 0-5 35422087-4 2022 SHMT2 knockout decreased the pools of purine and one-carbon units and delayed cell cycle progression in a manner that was rescued by formate, demonstrating that SHMT2-mediated one-carbon units are essential for BC cell proliferation. Carbon 180-186 serine hydroxymethyltransferase 2 Homo sapiens 161-166 12148096-5 2002 The effect of apo E2 triglyceride (TG)-rich lipoproteins, including remnant lipoproteins, on the accumulation of cholesteryl esters by human mesangial cells (HMCs) was estimated by measuring the stimulation of radioactive carbon-labeled oleate incorporation into cholesteryl esters. Carbon 222-228 molybdenum cofactor sulfurase Homo sapiens 158-162 35533478-2 2022 Herein, we propose a spatial confinement strategy mediated by Co2(OH)2CO3 nanosheet assemblies for achieving highly dispersed Co nanoparticles into hollow porous N-doped carbon shells (HP-Co@NCS). Carbon 170-176 complement C2 Homo sapiens 62-65 35571808-3 2022 Herein, we report the design of an anti-PD-L1 monoclonal antibody-conjugated magnetic-nanoparticle-attached yellow fluorescent carbon dot (YFCD) based magnetic-fluorescence nanoarchitecture for the selective separation and accurate identification of PD-L1-expressing exosomes. Carbon 127-133 CD274 molecule Homo sapiens 40-45 35352718-1 2022 Here, we report an efficient catalytic process that operates on a bi-metallic ZSM-5 supported catalyst (0.1Ga-1Zn/ZSM-5) for 100% carbon conversion of glycerol to produce 71.4C% liquid fuel-stock possessing a high concentration of alkyl-aromatics and octane potential (>97 RON) for fuel applications, achieved and reported for the first time to the best of our knowledge. Carbon 130-136 macrophage stimulating 1 receptor Homo sapiens 273-276 35571808-3 2022 Herein, we report the design of an anti-PD-L1 monoclonal antibody-conjugated magnetic-nanoparticle-attached yellow fluorescent carbon dot (YFCD) based magnetic-fluorescence nanoarchitecture for the selective separation and accurate identification of PD-L1-expressing exosomes. Carbon 127-133 CD274 molecule Homo sapiens 250-255 35344361-4 2022 In the present work, a melt extrusion-stretching method is utilized to fabricate biodegradable PLLA/poly(butylene adipate-co-butylene terephthalate)/carbon nanofiber (PLLA/PBAT/CNF) blend composites. Carbon 149-155 NPHS1 adhesion molecule, nephrin Homo sapiens 177-180 35624559-4 2022 First, we constructed a carbon interface modified with gold nanoflowers (Au NFs) based on screen-printed carbon electrodes (SPCE), which acted as nanostructures with larger specific surface area that increased the number of PSA capture antibodies and can further improve detection signal-to-noise (S/N) ratio. Carbon 24-30 kallikrein related peptidase 3 Homo sapiens 224-227 35396977-6 2022 Our transcriptome data suggest that Cd triggers ROS production and photosynthesis decline associated with increased proteolysis through ubiquitin-proteasome system (UPS)- and chloroplast-proteases and in this way brings about re-mobilization of N and C stores into amino acids and sugars. Carbon 251-252 ubiquitin Raphanus sativus 136-145 35431695-0 2022 Carbon Ion Induces Cell Death and G2/M Arrest Through pRb/E2F1Chk2/Cdc2 Signaling Pathway in X-ray Resistant B16F10 Melanoma Cells. Carbon 0-6 RB transcriptional corepressor 1 Mus musculus 54-57 12097662-1 2002 Methylenetetrahydrofolate reductase (MTHFR) polymorphisms may negatively influence one-carbon metabolism and increase health risks in women of reproductive age. Carbon 87-93 methylenetetrahydrofolate reductase Homo sapiens 0-35 12097662-1 2002 Methylenetetrahydrofolate reductase (MTHFR) polymorphisms may negatively influence one-carbon metabolism and increase health risks in women of reproductive age. Carbon 87-93 methylenetetrahydrofolate reductase Homo sapiens 37-42 12114564-1 2002 Squalene synthase (SS) represents a putative branch point in the isoprenoid biosynthetic pathway capable of diverting carbon flow specifically to the biosynthesis of sterols and, hence, is considered a potential regulatory point for sterol metabolism. Carbon 118-124 squalene synthase Nicotiana tabacum 0-17 12114564-1 2002 Squalene synthase (SS) represents a putative branch point in the isoprenoid biosynthetic pathway capable of diverting carbon flow specifically to the biosynthesis of sterols and, hence, is considered a potential regulatory point for sterol metabolism. Carbon 118-124 squalene synthase Nicotiana tabacum 19-21 35624559-4 2022 First, we constructed a carbon interface modified with gold nanoflowers (Au NFs) based on screen-printed carbon electrodes (SPCE), which acted as nanostructures with larger specific surface area that increased the number of PSA capture antibodies and can further improve detection signal-to-noise (S/N) ratio. Carbon 105-111 kallikrein related peptidase 3 Homo sapiens 224-227 35378040-3 2022 The two-step one-pot 1,6-conjugate addition provides effective access to a series of isatin-incorporated phosphate-bearing 1,6-adducts having two vicinal tertiary carbons with up to 90% yield and >20:1 dr. Carbon 163-170 protection of telomeres 1 Homo sapiens 17-22 12046046-4 2002 Methemoglobin levels normalized when the carbon filtration system of the portable dialysis machine was replaced with a larger unit to remove chloramines more effectively. Carbon 41-47 hemoglobin subunit gamma 2 Homo sapiens 0-13 35290040-8 2022 This resulted in the dissolution and loss of 47.2 +- 20.3% of initial Fe(III) (oxyhydr)oxides when conditions are wetter and more reduced, and new formation of Fe(III) minerals (33.7 +- 8.6% gain in comparison to initial Fe) in the late summer under more dry and oxic conditions, which also led to the sequestration of Fe-bound organic carbon. Carbon 336-342 general transcription factor IIE subunit 1 Homo sapiens 160-167 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 71-77 NPHS1 adhesion molecule, nephrin Homo sapiens 140-143 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 113-119 NPHS1 adhesion molecule, nephrin Homo sapiens 140-143 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 235-241 NPHS1 adhesion molecule, nephrin Homo sapiens 140-143 35142111-1 2022 Herein, a rational design of SnS2 nanosheets confined into bubble-like carbon nanoreactors anchored on N,S doped carbon nanofibers (SnS2 @C/CNF) is proposed to prepare the self-standing electrodes, which provides tunable void space on carbon fibers for the first time by introducing hollow carbon nanoreactors. Carbon 290-296 NPHS1 adhesion molecule, nephrin Homo sapiens 140-143 11997028-2 2002 Through the application of slow magic angle sample spinning and high-power proton decoupling, sufficient resolution and sensitivity were obtained in the carbon-13 spectrum to allow an assignment of many of the side chain resonances arising from uniformly carbon-13/nitrogen-15-labelled neurotensin(8-13) whilst bound to the neurotensin receptor. Carbon 153-159 neurotensin Rattus norvegicus 286-297 11997028-2 2002 Through the application of slow magic angle sample spinning and high-power proton decoupling, sufficient resolution and sensitivity were obtained in the carbon-13 spectrum to allow an assignment of many of the side chain resonances arising from uniformly carbon-13/nitrogen-15-labelled neurotensin(8-13) whilst bound to the neurotensin receptor. Carbon 153-159 neurotensin Rattus norvegicus 324-335 11997028-3 2002 Significant perturbations in carbon-13 chemical shift were observed upon the binding of the neurotensin(8-13) to the receptor. Carbon 29-35 neurotensin Rattus norvegicus 92-103 35016934-8 2022 PC1 revealed built-up and surface temperature vary inversely to the soil organic carbon and vegetation cover along about 20 km ( 10% of the shoreline extension). Carbon 81-87 proprotein convertase subtilisin/kexin type 1 Homo sapiens 0-3 35043967-11 2022 These results indicate that ACO3 impacts submergence tolerance through integration of carbon and nitrogen metabolism via the mitochondrial TCA cycle and impacts stress signaling during acclimation to stress. Carbon 86-92 aconitase 3 Arabidopsis thaliana 28-32 35420796-3 2022 The sensor is composed of single-walled carbon nanotubes functionalized with Abeta wherein Abeta-Abeta interactions drive the response. Carbon 40-46 amyloid beta (A4) precursor protein Mus musculus 77-82 35237782-2 2022 In the complexes (MX{eta2-Ph3PC(Me)BEt2}) (M = Cu, (Ag), Au; X = Cl, NTf2), the bonding is dominated by the highly nucleophilic ylidic carbon atom (L-type ligand). Carbon 135-141 nuclear transport factor 2 Homo sapiens 69-73 35248023-7 2022 Proteomic analysis supported the role of Znf1 and Bud21 in modulating levels of proteins associated with carbon metabolism, xylose utilisation, ribosomal protein synthesis, and others. Carbon 105-111 DNA-binding domain containing protein Saccharomyces cerevisiae S288C 41-45 12026973-3 2002 Carbon fractionation was reproducible in the PM1 and VAFB experiments, yielding similar enrichment factors (epsilon) of -2.0/1000 +/- 0.1/1000 to -2.4/1000 +/- 0.3/1000 for replicates in the PM1 experiment and -1.5/1000 +/- 0.1/1000 to -1.8/1000 +/- 0.1/1000 for replicates in the VAFB experiment. Carbon 0-6 transmembrane protein 11 Homo sapiens 45-48 12026973-3 2002 Carbon fractionation was reproducible in the PM1 and VAFB experiments, yielding similar enrichment factors (epsilon) of -2.0/1000 +/- 0.1/1000 to -2.4/1000 +/- 0.3/1000 for replicates in the PM1 experiment and -1.5/1000 +/- 0.1/1000 to -1.8/1000 +/- 0.1/1000 for replicates in the VAFB experiment. Carbon 0-6 transmembrane protein 11 Homo sapiens 191-194 35404034-1 2022 The work reports a modeling analysis of single-compound and binary adsorption of Pb2+ and Cd2+ ions from polluted water onto the activated carbon at room temperature. Carbon 139-145 CD2 molecule Homo sapiens 90-93 11950359-1 2002 Palladium on carbon combined with magnesium bromide catalyzed hydrogenation of Baylis-Hillman olefins to afford the corresponding aldol derivatives in a highly syn-diastereoselective manner is described. Carbon 13-19 synemin Homo sapiens 160-163 12007797-8 2002 Consequently, CAP- or CcpA-dependent catabolite repression serves as an autoregulatory device to keep sugar utilization at a certain level rather than to establish preferential utilization of certain carbon sources. Carbon 200-206 catabolite gene activator protein Escherichia coli 14-17 35103291-7 2022 Specific knockdown of ZAPL and ZAPS in RT7 cells decreased IFN-beta and C-X-C motif chemokine ligand 10 (CXCL10) expression induced by transfected Poly(I:C) and Poly(dA:dT). Carbon 154-155 C-X-C motif chemokine ligand 10 Homo sapiens 72-103 35103291-7 2022 Specific knockdown of ZAPL and ZAPS in RT7 cells decreased IFN-beta and C-X-C motif chemokine ligand 10 (CXCL10) expression induced by transfected Poly(I:C) and Poly(dA:dT). Carbon 154-155 C-X-C motif chemokine ligand 10 Homo sapiens 105-111 35121066-18 2022 Inhibition of CYP2D6, CYP2C19 and CYP3A4 increased with increasing chain-lengths between six and nine carbons. Carbon 102-109 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 22-29 35457903-3 2022 Then, ionic liquid (IL) and MnO2 NRs were utilized to modify a carbon paste electrode (CPE) surface (MnO2NR-IL/CPE) to voltammetrically sense the sulfanilamide (SAA). Carbon 63-69 carboxypeptidase E Homo sapiens 87-90 35075462-6 2022 Benefitting from the above combined advantages of the heterostructure and carbon layer protection, the AlP/SiP2@C electrode delivered a high reversible capacity (1482 mA h g-1 at the current density of 0.3 A g-1) and durable lifespan (516 mA h g-1 after 4000 cycles at a current density of 3 A g-1), which are superior to those of the binary AlP@C and SiP2@C composites. Carbon 74-80 gem nuclear organelle associated protein 6 Homo sapiens 107-111 11925209-3 2002 These reactions establish the syn stereochemistry about the newly formed carbon-carbon bond. Carbon 73-79 synemin Homo sapiens 30-33 11925209-3 2002 These reactions establish the syn stereochemistry about the newly formed carbon-carbon bond. Carbon 80-86 synemin Homo sapiens 30-33 12491245-0 2002 A one-dimensional BaI2 chain with five- and six-coordination, formed within a single-walled carbon nanotube. Carbon 92-98 adhesion G protein-coupled receptor B2 Homo sapiens 18-22 35457903-3 2022 Then, ionic liquid (IL) and MnO2 NRs were utilized to modify a carbon paste electrode (CPE) surface (MnO2NR-IL/CPE) to voltammetrically sense the sulfanilamide (SAA). Carbon 63-69 carboxypeptidase E Homo sapiens 108-114 35080666-10 2022 Overall, the proportion of lactate in the general catabolic carbon flow increased from 2.9% (wild type) to 28.5% in the LDH-overproducing mutant. Carbon 60-66 lactate dehydrogenase D Homo sapiens 120-123 35299236-2 2022 Here, a bimetallic FeCo2O4 spinel nanowire array grown on carbon cloth is proposed as an efficient electrocatalyst for the conversion of NO3- to NH3 with a high faradaic efficiency of up to 95.9% and a large NH3 yield of 4988 mug h-1 cm-2. Carbon 58-64 H1.5 linker histone, cluster member Homo sapiens 230-238 34653477-2 2022 To find a resolution to this issue, this study systematically evaluated the constituents of composite solid carbon (i.e., skeletons, carbon sources and crosslinking agents), and proposed a new multi-carbon source composite S1 (MCSC.S1). Carbon 199-205 solute carrier family 25 member 25 Homo sapiens 227-231 11966446-5 2002 beta-amino acids, with a specific side chain, can exist as the R or S isomers at either the alpha (C2) carbon or the beta (C3) carbon. Carbon 127-133 complement C3 Homo sapiens 117-125 35156775-2 2022 As was the case with carbon nanotubes, the cylindrical space of (4)cyclochrysenylene trapped multiple corannulene molecules in an array, and 1 : 2 complexes were commonly obtained with the corannulene guests with various halogen substituents (F, Cl, Br and I). Carbon 21-27 chromosome 12 open reading frame 73 Homo sapiens 250-258 11846793-2 2002 The subcellular location of the key glyoxylate-cycle enzyme malate synthase 1 (Mls1p), an SKL-terminated protein, was examined in yeast cells grown on different carbon sources. Carbon 161-167 malate synthase MLS1 Saccharomyces cerevisiae S288C 79-84 11846793-6 2002 The combined results indicated that Mls1p remained in the cytosol of cells grown on ethanol, and that targeting of Mls1p to the peroxisomes was advantageous to cells grown on oleic acid as a sole carbon source. Carbon 196-202 malate synthase MLS1 Saccharomyces cerevisiae S288C 115-120 34653477-5 2022 With MCSC.S1, total nitrification removal was enhanced by more than 48.56% through releasing carbon and absorbing the attached denitrifying bacteria. Carbon 93-99 solute carrier family 25 member 25 Homo sapiens 5-9 35098004-11 2022 When fed the HO diet, Trb3 KO mice had 17% higher mammary de novo synthesized FAs (<16 carbons; P int = 0.002) than WT mice. Carbon 87-94 tribbles pseudokinase 3 Mus musculus 22-26 35297628-4 2022 Comparison results show that reasonably good agreement is achieved between the SLD model and GCMC simulations for both the gas adsorption isotherms and discrete-density profiles in multiwalled carbon nanoslit and nanotube. Carbon 193-199 gastrin Homo sapiens 123-126 35162249-6 2022 (4) Carbon emissions per capita (CCE) were positively correlated with GRP per capita, industrial SO2 emissions per capita, and the proportion of employees in the secondary sector, and negatively correlated with population density and the proportion of employees in the tertiary sector. Carbon 4-10 gastrin releasing peptide Homo sapiens 70-73 35076523-4 2022 In particular, the electrical behavior and viscoelastic properties of a commercial jam were modulated by loading the jam with carbon nanotubes and graphene nanoplates. Carbon 126-132 F11 receptor Homo sapiens 83-86 35076523-4 2022 In particular, the electrical behavior and viscoelastic properties of a commercial jam were modulated by loading the jam with carbon nanotubes and graphene nanoplates. Carbon 126-132 F11 receptor Homo sapiens 117-120 11886753-1 2002 The effect of different carbon sources on the expression in Saccharomyces cerevisiae of the SWA2 alpha-amylase gene from Schwanniomyces occidentalis was studied from constructs containing its 5" region (-223 to +15), which were fused in-frame to the lacZ gene coding sequence. Carbon 24-30 Swa2p Saccharomyces cerevisiae S288C 92-96 35407223-0 2022 Wool-Based Carbon Fiber/MoS2 Composite Prepared by Low-Temperature Catalytic Hydrothermal Method and Its Application in the Field of Gas Sensors. Carbon 11-17 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 133-136 35021150-5 2022 Importantly, UCA1 specifically bound to and facilitated the combination of hnRNP I/L to the promoter of glutamic pyruvate transaminase 2 (GPT2), an enzyme transferring glutamate to alpha-ketoglutarate, resulting in upregulated expression of GPT2 and enhanced glutamine-derived carbons in the TCA cycle. Carbon 277-284 glutamic--pyruvic transaminase 2 Homo sapiens 104-136 35021150-5 2022 Importantly, UCA1 specifically bound to and facilitated the combination of hnRNP I/L to the promoter of glutamic pyruvate transaminase 2 (GPT2), an enzyme transferring glutamate to alpha-ketoglutarate, resulting in upregulated expression of GPT2 and enhanced glutamine-derived carbons in the TCA cycle. Carbon 277-284 glutamic--pyruvic transaminase 2 Homo sapiens 138-142 34989489-8 2022 NO3- was the chemical component with the largest mass concentration in haze, accounting for 25.2% of PM1; black carbon (BC) had the largest mass concentration on clean and dust storm days, accounting for 24.1% and 12.8% of PM1, respectively. Carbon 112-118 transmembrane protein 11 Homo sapiens 223-226 12017280-4 2002 The addition of NAC significantly reduced both the oxidation potential and carbon radical intensity of Moxa smoke. Carbon 75-81 X-linked Kx blood group Homo sapiens 16-19 35406202-3 2022 The composites exhibited good thermal conductivity, and compared with (MWCNTs-COOH/PEEK) with randomly distributed fillers, (PEK-C-OH-g-MWCNTs-COOH) composites showed a significant advantage, with the same carbon nanotube content, the thermal conductivity of PEK-C-OH-g-MWCNTs-COOH/PEEK (30 wt%) was 0. Carbon 129-130 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 125-128 35370268-0 2022 The Effect of Single-Walled Carbon Nanotubes on UDP-Glucuronosyltransferase 1A Activity in Human Liver. Carbon 28-34 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 48-78 35406202-3 2022 The composites exhibited good thermal conductivity, and compared with (MWCNTs-COOH/PEEK) with randomly distributed fillers, (PEK-C-OH-g-MWCNTs-COOH) composites showed a significant advantage, with the same carbon nanotube content, the thermal conductivity of PEK-C-OH-g-MWCNTs-COOH/PEEK (30 wt%) was 0. Carbon 129-130 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 259-262 35406202-3 2022 The composites exhibited good thermal conductivity, and compared with (MWCNTs-COOH/PEEK) with randomly distributed fillers, (PEK-C-OH-g-MWCNTs-COOH) composites showed a significant advantage, with the same carbon nanotube content, the thermal conductivity of PEK-C-OH-g-MWCNTs-COOH/PEEK (30 wt%) was 0. Carbon 206-212 eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens 125-128 11600130-9 2001 With the increase of the number of the carbon atoms of the alkyl chains, the contribution of CYP2A6 increased. Carbon 39-45 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 93-99 35286059-2 2022 Herein, the full hydrolysis process of the AB molecule on single Pt atom coordinated by two carbon atoms and one nitrogen atom (Pt1-C2N1) on nitrogen doped graphene is investigated using the density functional theory (DFT) method. Carbon 92-98 zinc finger protein 77 Homo sapiens 128-131 34985218-7 2022 The AOX adsorbed on activated carbon were cracked, burned, and gasified by the oxidative combustion method with a programmed heating mode. Carbon 30-36 acyl-CoA oxidase 1 Homo sapiens 4-7 34985218-17 2022 The established method improved the recoveries of AOX converted into inorganic halogens via oscillating adsorption of activated carbon, high-temperature oxidation combustion with a programmed heating mode, and secondary absorption using a porous absorption bottle. Carbon 128-134 acyl-CoA oxidase 1 Homo sapiens 50-53 11746604-4 2001 L-[(14)C]citrulline uptake measurements confirmed that suppressor mutations in CAN1 conferred uptake of this amino acid, while none of the mutant permeases had lost the ability to transport L-[(14)C]arginine. Carbon 7-8 arginine permease CAN1 Saccharomyces cerevisiae S288C 79-83 35229094-3 2022 Furthermore, a Sc(OTf)3/chiral N,N"-dioxide catalyzed asymmetric Michael addition of benzofuranone to MVK has been optimized for forging a chiral aromatic quaternary carbon center, which enables the formal synthesis of (+)-ent-herbertenolide. Carbon 166-172 POU class 5 homeobox 1 Homo sapiens 15-23 11448968-7 2001 The aft1 cells were unable to grow in aerobic conditions on plates containing raffinose as the sole carbon source. Carbon 100-106 DNA-binding transcription factor AFT1 Saccharomyces cerevisiae S288C 4-8 35287249-5 2022 Chit-S@g-C3 N4 -modified glassy carbon electrode (GCE) was employed for the electrochemical detection of omeprazole (OMZ) use in drug formulations. Carbon 32-38 chitinase 1 Homo sapiens 0-4 11431484-7 2001 We conclude that overlapping ORE and UAS1 elements in conjunction with their binding factors Pip2p-Oaf1p and Adr1p coordinate the carbon flux through beta-oxidation with peroxisome proliferation. Carbon 130-136 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 109-114 35239334-3 2022 The thermal expansion coefficients of the end member, Bi1.6Mg0.24Cu0.56Ta1.6O7.2-Delta, increase from 3.3 x 10-6 C-1 at room temperature up to 8.7 x 10-6 C-1 at 930 C. Rietveld refinement confirmed that the pyrochlore crystal structure is disordered with space group Fd3m:2 (Z = 8, no. Carbon 156-157 transmembrane BAX inhibitor motif containing 6 Homo sapiens 54-57 18968327-0 2001 Viscosity and binder composition effects on tyrosinase-based carbon paste electrode for detection of phenol and catechol. Carbon 61-67 tyrosinase Homo sapiens 44-54 35329594-4 2022 Composite printlets consisting of sintered carbon-stained polyamide (PA12) and metronidazole (Met) were manufactured by SLS to overcome the issue. Carbon 43-49 SAFB like transcription modulator Homo sapiens 94-97 35213803-0 2022 In Situ Monitoring of Extracellular K+ Using the Potentiometric Mode of Scanning Electrochemical Microscopy with a Carbon-Based Potassium Ion-Selective Tip. Carbon 115-121 TOR signaling pathway regulator Homo sapiens 152-155 11401551-2 2001 Chemical shift perturbations for both 15N and 1H nuclei arising from the interaction of isotopically enriched 15N cytochrome c with cytochrome c peroxidase have been observed. Carbon 5-6 cytochrome-c peroxidase Saccharomyces cerevisiae S288C 132-155 35213803-5 2022 Based on multi-wall carbon nanotubes as a transduction layer, the K+-ISE SECM tip realizes both the plotting of approach curves to position the tip for in situ detection and the recording of potential responses. Carbon 20-26 TOR signaling pathway regulator Homo sapiens 78-81 35213803-5 2022 Based on multi-wall carbon nanotubes as a transduction layer, the K+-ISE SECM tip realizes both the plotting of approach curves to position the tip for in situ detection and the recording of potential responses. Carbon 20-26 TOR signaling pathway regulator Homo sapiens 144-147 11375681-8 2001 The molecule possesses syn-syn conformation (both C=O bonds synperiplanar to the O-O bond) with O-O = 1.426(10) A and dihedral angle phi(C-O-O-C) = 86.5(32) degrees. Carbon 50-51 synemin Homo sapiens 23-26 35072350-1 2022 Functionalized porous materials could play a key role in improving the efficiency of gas separation processes as required by applications such as carbon capture and storage (CCS) and across the hydrogen value chain. Carbon 146-152 gastrin Homo sapiens 85-88 11375681-8 2001 The molecule possesses syn-syn conformation (both C=O bonds synperiplanar to the O-O bond) with O-O = 1.426(10) A and dihedral angle phi(C-O-O-C) = 86.5(32) degrees. Carbon 50-51 synemin Homo sapiens 27-30 11384242-1 2001 In search of a uroselective alpha1A subtype selective antagonist, a novel series of 6-OMe hexahydrobenz[e]isoindoles attached to a bicyclic heterocyclic moiety via a two-carbon linker was synthesized. Carbon 170-176 calcium voltage-gated channel subunit alpha1 A Homo sapiens 28-35 35232977-8 2022 Finally, we observed that RP5-998N21.4OE can enhance IFIT2- and IFIT3-mediated immune defense responses through activation of signal transducer and activator of transcription 1 (STAT1) signaling pathway in U251 astrocytoma cells under treatment with the viral mimetic polyinosinic: polycytidylic acid (poly I:C). Carbon 309-310 interferon induced protein with tetratricopeptide repeats 3 Homo sapiens 64-69 12483553-6 2001 Pho85 is a non-essential Cdk but its absence causes a broad spectrum of phenotypes such as constitutive expression of PHO5, inability to utilize non-fermentable carbon sources, defects in cell cycle progression, and so on. Carbon 161-167 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 0-5 35193687-10 2022 RPPA analysis and carbon-13 tracing analysis in these melanoma cells showed that IACS treatment decreased metabolic fuel utilization for fatty acid metabolism, but increased substrate availability for activation of the mevalonate pathway by HMGCR, creating a dependence on this pathway. Carbon 18-24 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 241-246 11311123-2 2001 After shifting the cells to a non-fermentable carbon source, the HXK2 gene is repressed and the HXK1 and GLK1 genes are rapidly de-repressed, producing the enzymes hexokinase 1 (Hxk1p) and glucokinase (Glk1p) respectively. Carbon 46-52 glucokinase Saccharomyces cerevisiae S288C 105-109 11311123-2 2001 After shifting the cells to a non-fermentable carbon source, the HXK2 gene is repressed and the HXK1 and GLK1 genes are rapidly de-repressed, producing the enzymes hexokinase 1 (Hxk1p) and glucokinase (Glk1p) respectively. Carbon 46-52 glucokinase Saccharomyces cerevisiae S288C 189-200 11311123-2 2001 After shifting the cells to a non-fermentable carbon source, the HXK2 gene is repressed and the HXK1 and GLK1 genes are rapidly de-repressed, producing the enzymes hexokinase 1 (Hxk1p) and glucokinase (Glk1p) respectively. Carbon 46-52 glucokinase Saccharomyces cerevisiae S288C 202-207 35103474-2 2022 Alkene geometry is selectively transferred to the newly formed carbon-carbon bond, resulting in stereochemical control of C1, C2, and C3 of the resulting 2-alkoxy-3-N-tosyl-4-alkyl-5-hexene products. Carbon 63-69 heterogeneous nuclear ribonucleoprotein C Homo sapiens 122-136 35103474-2 2022 Alkene geometry is selectively transferred to the newly formed carbon-carbon bond, resulting in stereochemical control of C1, C2, and C3 of the resulting 2-alkoxy-3-N-tosyl-4-alkyl-5-hexene products. Carbon 70-76 heterogeneous nuclear ribonucleoprotein C Homo sapiens 122-136 11372865-1 2001 The effect of oxygen-nitrogen atmosphere (N2 + 10%O2, N2 + 1%O2 and 99.999% N2) on the formation of PCB, PCDD and PCDF by the de novo synthetic reactions in the system consisting of extracted fly ash (from municipal waste incinerators--MWI), activated carbon, CuCl2 x 2H2O and NaCl at 340 degrees C was studied. Carbon 252-258 Pyruvate carboxylase Drosophila melanogaster 100-103 35140315-4 2022 Later, the bare carbon paste electrode (bare/CPE) was modified with polysorbate 80 and used to resolve the overlapped oxidation signals of dihydroxy benzene isomers. Carbon 16-22 carboxypeptidase E Homo sapiens 45-48 11323770-2 2001 MR-spectroscopy (MRS) records protons from tissue chemicals other than water, intrinsic phosphorus containing metabolites, sodium, potassium, carbon, nitrogen, and fluorine. Carbon 142-148 sterile alpha motif domain containing 11 Mus musculus 17-20 35211495-3 2021 Interactions are particularly relevant with the FADS1 and FADS2 genes, which encode key fatty acid desaturases in the pathway that converts LA and ALA to their long chain (>=20 carbons), highly unsaturated fatty acid (HUFA) counterparts. Carbon 177-184 fatty acid desaturase 1 Homo sapiens 48-53 11512838-2 2001 In this study, pitch-based activated carbon fibers (P20) were modified with nickel oxide particles. Carbon 37-43 tubulin polymerization promoting protein family member 3 Homo sapiens 52-55 35129437-8 2022 Together, our results indicate that that pH changes are a second messenger for transcriptional reprogramming during carbon starvation, and that the SNF5 QLC acts as a pH-sensor. Carbon 116-122 Snf5p Saccharomyces cerevisiae S288C 148-152 11223170-6 2001 Both the resulting core carbon particles and the organic extract enhanced ovalbumin specific IgE and IgG1 levels. Carbon 24-30 LOC105243590 Mus musculus 101-105 11181060-0 2001 Atomic force microscopy of RecA--DNA complexes using a carbon nanotube tip. Carbon 55-61 RAD51 recombinase Homo sapiens 27-31 35159798-0 2022 Comparing Commercial Metal-Coated AFM Tips and Home-Made Bulk Gold Tips for Tip-Enhanced Raman Spectroscopy of Polymer Functionalized Multiwalled Carbon Nanotubes. Carbon 146-152 TOR signaling pathway regulator Homo sapiens 76-79 11169757-3 2001 We demonstrate the importance of transcriptional activators Hap4, Cat8 and Pip2 for the carbon source-dependent regulation of MDH1, MDH2 and MDH3, respectively. Carbon 88-94 transcription factor HAP4 Saccharomyces cerevisiae S288C 60-64 11351993-7 2001 The -CF2- of the perfluoroalkyl groups for the three ethers was mainly converted to COF2 through the C-C cleavage; the conversion ratios from the carbons of the perfluoroalkyl group to COF2 were 48 +/- 10, 76 +/- 10, and 60 +/- 10% for C2F5OCH3, n-C3F7OCH3, and n-C5F11OCH3, respectively. Carbon 146-153 ATPase H+ transporting accessory protein 1 Homo sapiens 5-8 11073899-4 2000 Here we show, using DAL80 fused to the carbon-regulated GAL1,10 or copper-regulated CUP1 promoter, that GAT1 expression is inversely regulated by the level of DAL80 expression, i.e., as DAL80 expression increases, GAT1 expression decreases. Carbon 39-45 Dal80p Saccharomyces cerevisiae S288C 20-25 11073899-4 2000 Here we show, using DAL80 fused to the carbon-regulated GAL1,10 or copper-regulated CUP1 promoter, that GAT1 expression is inversely regulated by the level of DAL80 expression, i.e., as DAL80 expression increases, GAT1 expression decreases. Carbon 39-45 Dal80p Saccharomyces cerevisiae S288C 159-164 11073899-4 2000 Here we show, using DAL80 fused to the carbon-regulated GAL1,10 or copper-regulated CUP1 promoter, that GAT1 expression is inversely regulated by the level of DAL80 expression, i.e., as DAL80 expression increases, GAT1 expression decreases. Carbon 39-45 Dal80p Saccharomyces cerevisiae S288C 159-164 35128270-1 2022 Excessive CO2 emissions have resulted in global warming and are a serious threat to the life of people, various strategies have been implemented to cut carbon emissions, and one of them is the use of a gas separation membrane to capture CO2 effectively. Carbon 152-158 gastrin Homo sapiens 202-205 11101387-3 2000 In the dimers the units are linked through the C-11 position in ring C by an alkyl side chain of six or 10 carbon atoms, far from the hydroxy groups responsible for the VDR binding. Carbon 107-113 aldo-keto reductase family 1 member C4 Homo sapiens 47-51 35163908-4 2022 The Mo species, moreover, led to a decrease in the (C15 + C17)/(C16 + C18) ratio, which is beneficial from the viewpoint of carbon atom economy. Carbon 124-130 cytokine like 1 Homo sapiens 58-61 11101360-4 2000 A minimum of two carbon atoms separating the aromatic ring from the adenine-bearing carbon (C-3") was found to be essential for ADA activity equal to or slightly greater than that of (+)-EHNA. Carbon 17-23 adenosine deaminase Homo sapiens 128-131 11101360-4 2000 A minimum of two carbon atoms separating the aromatic ring from the adenine-bearing carbon (C-3") was found to be essential for ADA activity equal to or slightly greater than that of (+)-EHNA. Carbon 84-90 adenosine deaminase Homo sapiens 128-131 11076596-3 2000 It is found that the C-11 methoxy group directs the electrophilic attack to C-12 and C-14. Carbon 76-77 RNA polymerase III subunit K Homo sapiens 21-25 35046699-1 2022 Objective: The aim of this study is to assess the relationship between the single-nucleotide polymorphism (SNP) in the one-carbon metabolism pathway (MTR rs1805087; MTHFR rs1801133; ALDH1L1 rs2002287, rs2276731; DNMT1 rs16999593, rs2228611; DNMT3B rs2424908) and the risk of female breast cancer (BC) in a Chinese population. Carbon 123-129 DNA methyltransferase 3 beta Homo sapiens 241-247 11076596-7 2000 Contrasting behavior of the D-ring methyl-substituted 9 and the C-11 methoxy-substituted 10 dimers is remarkable in that unlike 9 which is readily cleaved to produce the monomeric arenium ion 3H(+)(), 10 is diprotonated at the two C-12 sites and at C-12/C-14 in each unit. Carbon 0-1 RNA polymerase III subunit K Homo sapiens 64-68 11030922-0 2000 Spin transport in interacting quantum wires and carbon nanotubes We present a general formulation of spin-dependent transport through a clean one-dimensional interacting quantum wire or carbon nanotube, connected to noncollinear ferromagnets via tunnel junctions. Carbon 48-54 spindlin 1 Homo sapiens 101-105 11030922-0 2000 Spin transport in interacting quantum wires and carbon nanotubes We present a general formulation of spin-dependent transport through a clean one-dimensional interacting quantum wire or carbon nanotube, connected to noncollinear ferromagnets via tunnel junctions. Carbon 186-192 spindlin 1 Homo sapiens 0-4 34974624-0 2022 UCP1 and AOX1a contribute to regulation of carbon and nitrogen metabolism and yield in Arabidopsis under low nitrogen stress. Carbon 43-49 plant uncoupling mitochondrial protein 1 Arabidopsis thaliana 0-4 11030922-0 2000 Spin transport in interacting quantum wires and carbon nanotubes We present a general formulation of spin-dependent transport through a clean one-dimensional interacting quantum wire or carbon nanotube, connected to noncollinear ferromagnets via tunnel junctions. Carbon 186-192 spindlin 1 Homo sapiens 101-105 35173113-0 2022 RIPK1 is a key factor in black carbon-induced cell death. Carbon 31-37 receptor interacting serine/threonine kinase 1 Homo sapiens 0-5 10998569-5 2000 In fact, considering all the mammalian cell sphingolipids, gangliosides, sulphatides, neutral glycosphingolipids, sphingomyelin and ceramides, it would seem that while the LCB with 18 carbons is the main component of all sphingolipids, only CNS gangliosides contain significant amounts of LCB with 20 carbons. Carbon 184-191 clathrin light chain B Homo sapiens 172-175 10998569-5 2000 In fact, considering all the mammalian cell sphingolipids, gangliosides, sulphatides, neutral glycosphingolipids, sphingomyelin and ceramides, it would seem that while the LCB with 18 carbons is the main component of all sphingolipids, only CNS gangliosides contain significant amounts of LCB with 20 carbons. Carbon 301-308 clathrin light chain B Homo sapiens 172-175 10988074-5 2000 While this conformation allows endoperoxide formation between C-11 and C-9, it also implies that a subsequent conformational rearrangement must occur to allow formation of the C-8/C-12 bond and to position C-15 for attack by a second molecule of oxygen. Carbon 62-63 complement C9 Homo sapiens 71-74 2558958-7 1989 ras1 ras2ts and ras1 cyr1ts mutants arrested in the G1 phase of the cell cycle at the restrictive temperature, and showed pleiotropic phenotypes to varying degrees even at a temperature permissive for growth (25 degrees), including slow growth, sporulation on rich media, increased accumulation of glycogen, impaired growth on nonfermentable carbon sources, heat-shock resistance, impaired growth on low concentrations of glucose, and lithium sensitivity. Carbon 342-348 Ras family GTPase RAS1 Saccharomyces cerevisiae S288C 0-4 10937722-2 2000 It was indicated that the epigallocatechin derivatives having the straight- or branched-acyl chain of C8 to C11 carbon atoms achieve marked effects. Carbon 112-118 aldo-keto reductase family 1 member C4 Homo sapiens 108-111 10929106-4 2000 In addition to AKIN10 and AKIN11, the deficiency of yeast snf4 mutant to grown on non-fermentable carbon source was suppressed by Arabidopsis Myb30, CAAT-binding factor Hap3b, casein kinase I, zinc-finger factors AZF2 and ZAT10, as well as orthologs of hexose/UDP-hexose transporters, calmodulin, SMC1-cohesin and Snf4. Carbon 98-104 casein kinase I Arabidopsis thaliana 176-191 10872804-2 2000 A thorough analysis of chemical shifts in correlation with C5-substituent electronegativity as well as calculations by SCF semi-empirical method of the formal charge localized on C6 carbon is discussed in terms of charge distribution for electron attracting and electron donating groups. Carbon 182-188 KIT ligand Homo sapiens 119-122 10777549-4 2000 HAOX1 is expressed primarily in liver and pancreas and is most active on the two-carbon substrate, glycolate, but is also active on 2-hydroxy fatty acids. Carbon 81-87 hydroxyacid oxidase 1 Homo sapiens 0-5 10744740-2 2000 First, two atp1 mutations (atp1-1 and atp1-2) were characterized that prevent the growth of yeast on non-fermentable carbon sources. Carbon 117-123 F1F0 ATP synthase subunit alpha Saccharomyces cerevisiae S288C 11-15 11017299-0 2000 Carbon nanotube based magnetic tunnel junctions Spin-coherent quantum transport in carbon nanotube magnetic tunnel junctions is investigated theoretically. Carbon 0-6 spindlin 1 Homo sapiens 48-52 10728670-0 2000 Transforming growth factor beta2 promotes glucose carbon incorporation into nucleic acid ribose through the nonoxidative pentose cycle in lung epithelial carcinoma cells. Carbon 50-56 transforming growth factor beta 2 Homo sapiens 0-32 10767172-6 2000 DMGDH and SDH also utilize a noncovalently bound folate coenzyme that receives the "1-carbon" groups that are removed by DMGDH and SDH, forming "active formaldehyde." Carbon 86-92 dimethylglycine dehydrogenase Homo sapiens 0-5 10767172-6 2000 DMGDH and SDH also utilize a noncovalently bound folate coenzyme that receives the "1-carbon" groups that are removed by DMGDH and SDH, forming "active formaldehyde." Carbon 86-92 sarcosine dehydrogenase Homo sapiens 10-13 10767172-6 2000 DMGDH and SDH also utilize a noncovalently bound folate coenzyme that receives the "1-carbon" groups that are removed by DMGDH and SDH, forming "active formaldehyde." Carbon 86-92 dimethylglycine dehydrogenase Homo sapiens 121-126 10767172-6 2000 DMGDH and SDH also utilize a noncovalently bound folate coenzyme that receives the "1-carbon" groups that are removed by DMGDH and SDH, forming "active formaldehyde." Carbon 86-92 sarcosine dehydrogenase Homo sapiens 131-134 10646517-5 2000 We found that several proteins tyrosine-phosphorylated in response to BDNF showed enhanced levels of tyrosine phosphorylation in cultured neurons infected with C/S mutant adenovirus in comparison with those infected with the wild-type Shp-2 adenovirus. Carbon 160-161 brain-derived neurotrophic factor Rattus norvegicus 70-74 10646517-7 2000 We found that the Shp-2-binding protein, brain immunoglobulin-like molecule with tyrosine-based activation motifs (BIT), was strongly tyrosine-phosphorylated in response to BDNF in cultured neurons expressing the C/S mutant of Shp-2. Carbon 213-214 brain-derived neurotrophic factor Rattus norvegicus 173-177 12903344-5 2000 The use of a carbon nanotube (CNT) AFM tip enabled high resolution to reveal the periodicity of RecA-dsDNA filaments. Carbon 13-19 RAD51 recombinase Homo sapiens 96-100 10579859-0 1999 Configurative correlation and conformational analysis of strictosidine and vincoside derivatives On the basis of the configuration of C-15 of the secologanin unit, using detailed NMR analysis, the configuration of C-3, the solution conformation around C-14, and the glucosidic bridge, as well as those of the dihydropyran and tetrahydropyridine rings, were determined in the vincosamide and strictosamide derivatives 4b and 5b. Carbon 0-1 placenta associated 8 Homo sapiens 134-138 10510295-1 1999 The glucokinase gene GLK1 of the yeast Saccharomyces cerevisiae is transcriptionally regulated in response to the carbon source of the growth medium. Carbon 114-120 glucokinase Saccharomyces cerevisiae S288C 4-15 10510295-1 1999 The glucokinase gene GLK1 of the yeast Saccharomyces cerevisiae is transcriptionally regulated in response to the carbon source of the growth medium. Carbon 114-120 glucokinase Saccharomyces cerevisiae S288C 21-25 10510295-12 1999 The combinatorial effect of the entire region leads to the regulated transcription of GLK1, i.e., silent in media with glucose and other preferred carbon sources, such as fructose or mannose, and increased levels of expression upon glucose depletion. Carbon 147-153 glucokinase Saccharomyces cerevisiae S288C 86-90 10517852-4 1999 Experiments were motivated by the potential for a reduced invertase/Suc synthase balance to alter the impact of respiratory and/or membrane carbon flux on sugar signaling. Carbon 140-146 invertase 2 Zea mays 58-67 10529990-0 1999 Evaluation of activated carbon filters for removal of ozone at the PPB level. Carbon 24-30 histatin 1 Homo sapiens 67-70 10452956-4 1999 A gal7 yeast strain harboring a plasmid containing cloned hIMPase grows on galactose as a sole carbon source. Carbon 95-101 UDP-glucose:hexose-1-phosphate uridylyltransferase Saccharomyces cerevisiae S288C 2-6 10468558-0 1999 Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids. Carbon 154-160 2-hydroxyacyl-CoA lyase 1 Homo sapiens 51-79 10468558-0 1999 Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids. Carbon 161-167 2-hydroxyacyl-CoA lyase 1 Homo sapiens 51-79 10468558-5 1999 Hence the enzyme catalyzes a carbon-carbon cleavage, and we propose calling it 2-hydroxyphytanoyl-CoA lyase. Carbon 29-35 2-hydroxyacyl-CoA lyase 1 Homo sapiens 79-107 10468558-5 1999 Hence the enzyme catalyzes a carbon-carbon cleavage, and we propose calling it 2-hydroxyphytanoyl-CoA lyase. Carbon 36-42 2-hydroxyacyl-CoA lyase 1 Homo sapiens 79-107 10452541-1 1999 Transketolase (TK) reactions play a crucial role in tumor cell nucleic acid ribose synthesis utilizing glucose carbons, yet, current cancer treatments do not target this central pathway. Carbon 111-118 transketolase Mus musculus 0-13 10452541-1 1999 Transketolase (TK) reactions play a crucial role in tumor cell nucleic acid ribose synthesis utilizing glucose carbons, yet, current cancer treatments do not target this central pathway. Carbon 111-118 transketolase Mus musculus 15-17 10328823-6 1999 The ACN8, ACN17, and ACN18 genes were isolated by functional complementation of the respective mutant"s inability to utilize acetate as a carbon and energy source, and these genes were shown to encode subunits of metabolic enzymes. Carbon 138-144 succinate dehydrogenase membrane anchor subunit SDH4 Saccharomyces cerevisiae S288C 21-26 10367351-2 1999 The capacity of the straight chain primary alcohols (methanol, ethanol, 1-propanol, 1-butanol and 1-pentanol) to release the enzymes glutamate-pyruvate transaminase (GPT), lactate dehydrogenase (LDH) and glutamate dehydrogenase (GLDH) into the perfusate was strongly correlated with their carbon chain length. Carbon 289-295 glutamic--pyruvic transaminase Rattus norvegicus 133-164 10367351-2 1999 The capacity of the straight chain primary alcohols (methanol, ethanol, 1-propanol, 1-butanol and 1-pentanol) to release the enzymes glutamate-pyruvate transaminase (GPT), lactate dehydrogenase (LDH) and glutamate dehydrogenase (GLDH) into the perfusate was strongly correlated with their carbon chain length. Carbon 289-295 glutamic--pyruvic transaminase Rattus norvegicus 166-169 10102376-0 1999 Dbf2 is implicated in a Cbt1-dependent pathway following a shift from glucose to galactose or non-fermentable carbon sources in Saccharomyces cerevisiae. Carbon 110-116 Cbt1p Saccharomyces cerevisiae S288C 24-28 10102376-3 1999 Screening of two S. cerevisiae cDNA libraries led to the identification of CBT1 as a gene which, if overexpressed simultaneously with CDC14, results in the rescue of the dbJ2-2 mutation at restrictive temperature on galactose-based medium, as well as on media containing non-fermentable carbon sources such as glycerol, lactate and acetate. Carbon 287-293 Cbt1p Saccharomyces cerevisiae S288C 75-79 9987137-12 1999 Although the null mutant can grow on both fermentable and non-fermentable carbon sources at lower temperatures, it cannot form colonies at 37 degrees C. In conclusion, CRD1 expression is controlled by factors affecting mitochondrial development, but not by the phospholipid precursors inositol and choline. Carbon 74-80 cardiolipin synthase Saccharomyces cerevisiae S288C 168-172 18944809-10 1999 The formulation also provided good control when stored for 6 months at room temperature or at 4 degrees C. Chitinase and beta-1,3-glucanase enzymes were produced when the strains were grown in the presence of colloidal chitin as the sole carbon source. Carbon 238-244 acidic endochitinase Cucumis sativus 107-116 9857024-6 1998 Further analyses revealed that for aldopyranosyl substrates, the activation energy barrier is affected most by the presence of a C-6 carbon and by the configuration of the C-2 hydroxyl, whereas the binding energy is affected modestly by the configuration and substituents at C-2, C-4, and C-5. Carbon 133-139 complement C2 Cavia porcellus 172-175 9857024-6 1998 Further analyses revealed that for aldopyranosyl substrates, the activation energy barrier is affected most by the presence of a C-6 carbon and by the configuration of the C-2 hydroxyl, whereas the binding energy is affected modestly by the configuration and substituents at C-2, C-4, and C-5. Carbon 133-139 complement C2 Cavia porcellus 275-278 9931424-3 1998 The bul1 bul2 double disruptant was sensitive to various stresses, such as high temperature, salts, and a non-fermentable carbon source. Carbon 122-128 ubiquitin-ubiquitin ligase BUL1 Saccharomyces cerevisiae S288C 4-8 9931424-3 1998 The bul1 bul2 double disruptant was sensitive to various stresses, such as high temperature, salts, and a non-fermentable carbon source. Carbon 122-128 ubiquitin-ubiquitin ligase BUL2 Saccharomyces cerevisiae S288C 9-13 9873742-7 1998 The function of this group could be equivalent to that of the C-9(OH)/C-13 (C = O) motif in phorbol esters, which also appears free of interactions in the phorbol ester/C1b complex. Carbon 62-63 homeobox C13 Homo sapiens 70-74 9894911-1 1998 Transcriptional regulation of the yeast cytochrome c1 gene (CYT1) in response to oxygen and carbon source is mediated by Haplp and the Hap2 complex. Carbon 92-98 ubiquinol--cytochrome-c reductase catalytic subunit CYT1 Saccharomyces cerevisiae S288C 60-64 11672334-4 1998 The homolytic bond dissociation enthalpies (BDEs) of the acidic C-H bonds determined by using eq 1 reveal that an alpha-Ph(3)As(+) group increases the BDE value of the adjacent acidic C-H bond by 2-5 kcal/mol, whereas the substituent effects for an alpha-Ph(3)P(+) or alpha-(n-Bu)(3)P(+) group was found to be dependent on the nature of the substituents attached to the alpha-carbon atom. Carbon 376-382 homeobox D13 Homo sapiens 44-47 9696750-8 1998 Growth phenotype analyses suggest that the external NADH dehydrogenase activity of Ndh1p is important for optimum cellular growth with a number of nonfermentable carbon sources, including ethanol. Carbon 162-168 NADH-ubiquinone reductase (H(+)-translocating) NDE1 Saccharomyces cerevisiae S288C 83-88 9696750-9 1998 Codisruption of NDH1 and genes encoding malate dehydrogenases essentially eliminates growth on nonfermentable carbon sources, suggesting that the external mitochondrial NADH dehydrogenase and the malate-aspartate shuttle may both contribute to reoxidation of cytosolic NADH under these growth conditions. Carbon 110-116 NADH-ubiquinone reductase (H(+)-translocating) NDE1 Saccharomyces cerevisiae S288C 16-20 9642197-6 1998 The resultant rpoS mutant of P.putida, C1R1, showed reduced survival of carbon starvation and reduced cross-protection against other types of stress in cells starved for carbon, in particular after a challenge with ethanol. Carbon 72-78 RNA polymerase sigma factor RpoS Pseudomonas putida KT2440 14-18 9642197-6 1998 The resultant rpoS mutant of P.putida, C1R1, showed reduced survival of carbon starvation and reduced cross-protection against other types of stress in cells starved for carbon, in particular after a challenge with ethanol. Carbon 170-176 RNA polymerase sigma factor RpoS Pseudomonas putida KT2440 14-18 9642197-8 1998 The RpoS protein of P. putida controls the expression of more than 50 peptides, which are normally expressed in cells after a short period of carbon starvation. Carbon 142-148 RNA polymerase sigma factor RpoS Pseudomonas putida KT2440 4-8 10375776-7 1998 (2) The carbon atom (C11) had the most positive net atom charge. Carbon 8-14 RNA polymerase III subunit K Homo sapiens 21-24 10375776-9 1998 (3) The bond order of carbon-oxygen bond (C11-O10) was invariant across the series of the compounds. Carbon 22-28 RNA polymerase III subunit K Homo sapiens 42-45 9614098-6 1998 The cls1::TRP1 null mutant grew on both fermentable and non-fermentable carbon sources but more poorly on the latter. Carbon 72-78 cardiolipin synthase Saccharomyces cerevisiae S288C 4-8 9618400-1 1998 Early molecular modeling studies with Delta9-tetrahydrocannabinol (Delta9-THC) reported that three discrete regions which interact with brain cannabinoid (CB1) receptors corresponded to the C-9 position of the cyclohexene ring, the phenolic hydroxyl and the carbon side chain at the C3 position. Carbon 258-264 cannabinoid receptor 1 Rattus norvegicus 155-158 9558333-9 1998 A sulfide bridge is formed between C-11 and C-14, which interrupts the conjugation. Carbon 35-36 anti-Mullerian hormone receptor type 2 Rattus norvegicus 44-48 9545322-6 1998 Disruption of the PGS1 gene in a haploid strain of yeast did not lead to a loss of viability but did result in a dependence on a fermentable carbon source for growth, a temperature sensitivity for growth, and a petite lethal phenotype. Carbon 141-147 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 18-22 29711260-0 1998 Crystal Structures of Chiral Diastereoisomers of a Carbon-Based High-Spin Molecule. Carbon 51-57 spindlin 1 Homo sapiens 69-73 20700828-3 1998 This approach removes the main relaxation source (the dipolar coupling to the directly bound 13C spin) and leads to a significant reduction of the proton and carbon relaxation rates. Carbon 158-164 spindlin 1 Homo sapiens 97-101 9879512-5 1998 The analogues in which the oxygen atom is closest to the alpha-carbon (9 and 10) inactivate MAO B, but activity slowly returns with time. Carbon 63-69 monoamine oxidase B Homo sapiens 92-97 9462830-2 1998 A cls1 deletion strain is viable on glucose, galactose, ethanol, glycerol and lactate containing media, although the growth rate on non-fermentable carbon sources is decreased. Carbon 148-154 cardiolipin synthase Saccharomyces cerevisiae S288C 2-6 9462830-3 1998 Mitochondria of the cls1 mutant are devoid of cardiolipin but accumulate the cardiolipin precursor phosphatidylglycerol when grown on non-fermentable carbon sources. Carbon 150-156 cardiolipin synthase Saccharomyces cerevisiae S288C 20-24 10022068-5 1998 Together with the co-disposal of organic wastes, algal biomass is generated as an independent carbon source for SRB production. Carbon 94-100 chaperonin containing TCP1 subunit 4 Homo sapiens 112-115 23899391-5 1998 In dGMP and in dAMP 48 % and 86 % of adducts were covalently bound to the C-2 carbon of BMO. Carbon 78-84 complement component 2 (within H-2S) Mus musculus 74-77 9428654-1 1997 In the present study, we demonstrated that the attachment of the nonpolar isopropylic carbon chain in the nitrogen of oxamate, converted this competitive inhibitor of LDH isozymes into a powerful selective inhibitor of mouse LDH-C4. Carbon 86-92 lactate dehydrogenase C Mus musculus 225-231 9377092-1 1997 The monoamine oxidases A and B (MAO-A and MAO-B) catalyze the alpha-carbon oxidation of a variety of 4-substituted 1-methyl-1,2,3,6-tetrahydropyridine derivatives to yield the corresponding 2,3-dihydropyridinium species. Carbon 68-74 monoamine oxidase B Homo sapiens 42-47 9153230-4 1997 Comparison of these methylation patterns indicates that the o2 tissue-specific expression does not result from the demethylation of any specific C residue and that, in vivo, O2 interacts with a methylated target sequence. Carbon 0-1 regulatory protein opaque-2 Zea mays 60-62 9153230-4 1997 Comparison of these methylation patterns indicates that the o2 tissue-specific expression does not result from the demethylation of any specific C residue and that, in vivo, O2 interacts with a methylated target sequence. Carbon 0-1 regulatory protein opaque-2 Zea mays 174-176 9194712-4 1997 Carbon sources that caused strong catabolite repression of beta-galactosidase lowered the concentration of both cAMP and the cAMP receptor protein (CRP). Carbon 0-6 catabolite gene activator protein Escherichia coli 125-146 9194712-4 1997 Carbon sources that caused strong catabolite repression of beta-galactosidase lowered the concentration of both cAMP and the cAMP receptor protein (CRP). Carbon 0-6 catabolite gene activator protein Escherichia coli 148-151 9194712-11 1997 These results, combined with the fact that both the cAMP and the CRP levels are lowered by glucose 6-phosphate, lactose and gluconate, lead to the conclusion that the decreased cAMP and CRP levels are the cause of catabolite repression by these non-PTS carbon sources. Carbon 253-259 catabolite gene activator protein Escherichia coli 186-189 9108135-3 1997 First, SOD2 transcription is activated 10-fold by growth on a non-fermentable carbon source via the heme activator protein (Hap) 2-3-4-5 complex. Carbon 78-84 superoxide dismutase SOD2 Saccharomyces cerevisiae S288C 7-11 9132024-0 1997 Evidence that cobalt-carbon bond homolysis is coupled to hydrogen atom abstraction from substrate in methylmalonyl-CoA mutase. Carbon 21-27 methylmalonyl-CoA mutase Homo sapiens 101-125 9037020-9 1997 The FAT-1 protein is an omega-3 fatty acyl desaturase that recognizes a range of 18- and 20-carbon omega-6 substrates. Carbon 92-98 Omega-3 fatty acid desaturase fat-1 Caenorhabditis elegans 4-9 9242908-8 1997 The best-characterized B12-dependent mutases that catalyze carbon skeleton rearrangement, for which methylmalonyl-coenzyme A mutase is the prototype, also bind cobalamin cofactors with histidine as the cobalt ligand, although other cobalamin-dependent mutases do not appear to utilize histidine ligation. Carbon 59-65 methylmalonyl-CoA mutase Homo sapiens 100-131 9523451-6 1997 A substantial improvement in BOD1/TOC could be achieved, but it required the mineralization of at least 80% of the organic carbon originally in the water. Carbon 123-129 rhomboid 5 homolog 2 Homo sapiens 34-37 8985169-7 1996 A study of the specificity of fatty acids revealed that long-chain fatty acids of more than 16 carbons chain length had a suppressive effect on the CPS mRNA level induced by dexamethasone and that the presence of double bonds enhanced the effect. Carbon 95-102 carbamoyl-phosphate synthetase 1 Mus musculus 148-151 8702805-8 1996 Calmodulin binding to the recombinant reductase protein increased its rate of NADPH-dependent flavin reduction and its rate of electron transfer to cytochrome c, FeCN6, or dichlorophenolindophenol to fully match the rate increases achieved when calmodulin bound to native full-length nNOS. Carbon 28-29 nitric oxide synthase 1 Rattus norvegicus 284-288 8753814-3 1996 The overall order of the binding of homoribopolymer for the NS3 protein was poly(U) > > poly(A) > poly(G), poly(C). Carbon 121-122 KRAS proto-oncogene, GTPase Homo sapiens 60-63 8753648-3 1996 Three genes were found that restored partial growth on non-fermentable carbon sources, all of which affect the biogenesis of respiratory competent mitochondria: PIM1(LON) encodes a matrix-localized ATP-dependent protease involved in the turnover of matrix proteins; OXA1(PET1402) encodes a putative mitochondrial inner membrane protein involved in the biogenesis of the respiratory chain; and MBA1 encodes a mitochondrial protein required for optimal respiratory growth. Carbon 71-77 ATP-dependent Lon protease PIM1 Saccharomyces cerevisiae S288C 161-165 8762074-6 1996 Likewise, the cyclo-oxygenase inhibitor, indomethacin, markedly potentiated the contractile responses to ET-1, but not to SRTX-c. Carbon 14-15 endothelin-1 Cavia porcellus 105-109 8780053-1 1996 Prosaposin, a 517-amino-acid glycoprotein, not only acts as the precursor of saposin A, B, C, and D but also possesses neurotrophic activity to rescue hippocampal CA1 neurons from ischemic damage in vivo and to promote neurite extension of neuroblastoma cells in vitro. Carbon 91-92 prosaposin Homo sapiens 0-10 8600988-7 1996 These compounds have a saturated double bond in the polyene side chain between either the 7, 8 or 9, 10 carbon atoms and are highly RAR or RXR selective, respectively (as shown by receptor binding, transactivation activity and the ability to induce RXR homodimer formation). Carbon 104-110 retinoid X receptor alpha Homo sapiens 139-142 8911636-2 1996 Samples containing nickel (III), of low crystallinity, with small particle size and high surface areas can in the presence of H2O2, cause the generation of the hydroxyl radical (as detected by spin trapping with 5,5-dimethyl-1-pyrroline N-oxide or DMPO) and/or another highly reactive species capable of cleaving the C-S bond in dimethyl sulphoxide. Carbon 317-318 spindlin 1 Homo sapiens 193-197 8616944-1 1996 BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) synthesizes 5-methyltetrahydrofolate, the major carbon donor in remethylation of homocysteine to methionine. Carbon 104-110 methylenetetrahydrofolate reductase Homo sapiens 12-47 8616944-1 1996 BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) synthesizes 5-methyltetrahydrofolate, the major carbon donor in remethylation of homocysteine to methionine. Carbon 104-110 methylenetetrahydrofolate reductase Homo sapiens 49-54 8848442-4 1996 These results, in conjunction with findings on other structurally similar molecules suggest that, of the molecules tested, (a) a hydrophobic group at the C-3 attached carbon is critical for analgesia; (b) a hydrophobic C-2 ester group can enhance analgesic activity (e.g., cocaethylene); (c) the N-methyl position is minimally important for analgesia; and (d) isomeric configurational changes can influence analgesia. Carbon 167-173 complement C3 Rattus norvegicus 154-157 8872458-9 1995 Extension of the D-ring C-2 alcohol by one carbon in length resulted in a pair of structures, for which the greatest affinity for the CB1 receptor occurred for the hydroxymethyl group in the axial conformation [(+/-)-CP-55,244]. Carbon 43-49 cannabinoid receptor 1 Rattus norvegicus 134-137 8576644-12 1995 The torsion angle sequence along the double bond extending from the oleyl carbons C7 to C13 is tscsst (173 degrees, -152 degrees, -17 degrees, -157 degrees, -163 degrees, -178 degrees). Carbon 74-81 homeobox C13 Homo sapiens 88-91 2611236-3 1989 The latter two conformers may be distinguished by smaller but still significant differences in the carbon chemical shifts at the C-2" and C-4" positions. Carbon 99-105 complement C2 Bos taurus 129-132 8553693-5 1995 The PEL1 gene was moderately expressed irrespective of the state of the mitochondrial genome and the nature of the carbon sources. Carbon 115-121 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Saccharomyces cerevisiae S288C 4-8 7650690-6 1995 Therefore, a one-carbon bridge replaces the 19-methyl group and 9E-double bond of 9-cis-retinoic acid and is further functionalized by inclusion in an isopropylidene group, a dioxolane ring, or a cyclopropane ring for optimal RXR alpha activity and selectivity. Carbon 17-23 retinoid X receptor alpha Homo sapiens 226-235 2768238-4 1989 The kinetics of the LCAT reaction were measured for p-nitrophenyl esters of fatty acids having up to six (C-6) carbons in length. Carbon 111-118 lecithin-cholesterol acyltransferase Homo sapiens 20-24 7578368-1 1995 Four benzophenanthridine phosphoramidite reagents have been prepared in which the linker chain between the benzophenanthridine and the phosphoramidite moiety is attached to C-2, C-6, C-9, and C-12 of the benzophenanthridine ring system. Carbon 173-174 complement C9 Homo sapiens 183-186 2788162-4 1989 These results indicate that the monoamine oxidase B-catalyzed oxidation of this substrate may not proceed via a reaction pathway involving alpha-carbon deprotonation of an aminium radical intermediate. Carbon 145-151 monoamine oxidase B Homo sapiens 32-51 7741711-6 1995 Increased PLD activity is detected in membranes when either haploid or diploid cells are incubated in the presence of a non-fermentable carbon source. Carbon 136-142 phospholipase D Saccharomyces cerevisiae S288C 10-13 7741711-7 1995 Membrane PLD activity increases within 10 min after diploid cells are placed in a sporulation-inducing medium lacking nitrogen and containing a non-fermentable carbon source. Carbon 160-166 phospholipase D Saccharomyces cerevisiae S288C 9-12 7732723-3 1995 In this paper, we describe the transcriptional regulation of the HXK1, HXK2 and GLK1 genes in the hope of revealing differences in the steady-state levels of mRNA associated with a particular carbon source used in the culture medium. Carbon 192-198 glucokinase Saccharomyces cerevisiae S288C 80-84 7618520-10 1995 Inhibitors with relatively short carbon chain lengths (i.e. four to six carbons) were found to be more potent at inhibiting brain MAO-B activity in vivo especially after oral administration. Carbon 33-39 monoamine oxidase B Homo sapiens 130-135 7618520-10 1995 Inhibitors with relatively short carbon chain lengths (i.e. four to six carbons) were found to be more potent at inhibiting brain MAO-B activity in vivo especially after oral administration. Carbon 72-79 monoamine oxidase B Homo sapiens 130-135 2553632-8 1989 For DPDPE, however, this was only possible with a positive dihedral angle for the disulfide bond due to the presence of the beta-carbon methyls of Pen2. Carbon 129-135 presenilin enhancer, gamma-secretase subunit Homo sapiens 147-151 2751988-2 1989 Normal mode calculations on 13-cis-retinal Schiff bases demonstrate that the C15-D rock and N-CLys stretch are strongly coupled for C = N-syn chromophores and weakly coupled for C = N-anti chromophores. Carbon 77-78 synemin Homo sapiens 138-141 7564877-4 1995 A similar ranking order for DAT availability was obtained with [C-11]cocaine. Carbon 64-65 solute carrier family 6 member 3 Homo sapiens 28-31 2751988-2 1989 Normal mode calculations on 13-cis-retinal Schiff bases demonstrate that the C15-D rock and N-CLys stretch are strongly coupled for C = N-syn chromophores and weakly coupled for C = N-anti chromophores. Carbon 94-95 synemin Homo sapiens 138-141 2641283-6 1989 From incubations with 10 mM 13C-labelled pyruvate, we calculated from the relative enrichments of the glutamate carbon atoms that the ratio of pyruvate carboxylase to pyruvate dehydrogenase is 1.44 +/- 0.04 in rabbit renal proximal tubules. Carbon 112-118 LOW QUALITY PROTEIN: pyruvate carboxylase, mitochondrial Oryctolagus cuniculus 143-163 7527207-6 1994 Activation of the distal portion of the valine catabolic pathway correlates with significant increases in enzyme protein and mRNA levels for 3-hydroxyisobutyrate dehydrogenase and methylmalonate semialdehyde dehydrogenase, and this establishes the pathway in 3T3-L1 adipocytes for utilization of valine carbon for lipogenesis. Carbon 303-309 3-hydroxyisobutyrate dehydrogenase Mus musculus 141-175 2914888-3 1989 We have recently proposed a covalent catalytic mechanism for LCAT in which lecithin cleavage proceeds via the formation of a transition state tetrahedral adduct between the oxygen atom of the catalytic serine residue and the sn-2-carbonyl carbon atom of the substrate (Jauhiainen, M., Ridgway, N.D., and Dolphin, P.J. Carbon 230-236 lecithin-cholesterol acyltransferase Homo sapiens 61-65 7949149-3 1994 Butyrate (4 carbons) increased the activity of the human A gamma-globin gene promoter up to 123 times. Carbon 12-19 hemoglobin subunit gamma 1 Homo sapiens 57-71 2914888-11 1989 The inhibition is attributed to the formation of a tetrahedral adduct between the catalytic serine residue of LCAT and the sn-2-carbonyl carbon atom of the analogues which is stabilized by the electronegative fluorine atoms present upon the carbon atom alpha to the carbonyl carbon. Carbon 128-134 lecithin-cholesterol acyltransferase Homo sapiens 110-114 2914888-11 1989 The inhibition is attributed to the formation of a tetrahedral adduct between the catalytic serine residue of LCAT and the sn-2-carbonyl carbon atom of the analogues which is stabilized by the electronegative fluorine atoms present upon the carbon atom alpha to the carbonyl carbon. Carbon 137-143 lecithin-cholesterol acyltransferase Homo sapiens 110-114 7895165-3 1994 In vitro, CLIP dissociation from DR alpha beta dimers occurs at different rates depending on the allele, and is facilitated by low pH and by detergents containing 8-10 carbon unbranched hydrocarbons, or by primary aliphatic amines or carboxylic acids. Carbon 168-174 CAP-Gly domain containing linker protein 1 Homo sapiens 10-14 2914888-11 1989 The inhibition is attributed to the formation of a tetrahedral adduct between the catalytic serine residue of LCAT and the sn-2-carbonyl carbon atom of the analogues which is stabilized by the electronegative fluorine atoms present upon the carbon atom alpha to the carbonyl carbon. Carbon 137-143 lecithin-cholesterol acyltransferase Homo sapiens 110-114 2721336-4 1989 ANOVA comparison of the two groups showed C-exposed infants were more reactive in general, as indicated by a larger glabellar reflex, and more responsive to auditory stimuli, as indicated by an increased blink when the tone accompanied the tap (p less than 0.05). Carbon 42-43 nuclear RNA export factor 1 Homo sapiens 240-243 7996046-5 1994 NAC reduced ferricytochrome c and increased dose-dependently Fe(III)-citrate and Fe(III)-EDTA-catalyzed hydroxyl radical formation in a system using glucose and glucose oxidase. Carbon 8-9 X-linked Kx blood group Homo sapiens 0-3 8027080-13 1994 Strains lacking a functional CKB2 gene appear to grow normally on both fermentable and non-fermentable carbon sources, mate and sporulate normally, and display normal resistance to nitrogen starvation and heat shock. Carbon 103-109 casein kinase 2 regulatory subunit CKB2 Saccharomyces cerevisiae S288C 29-33 8030784-4 1994 However, if a double bond is present at the C-2 or C-3 carbon atoms, this cis=CH stretch absorption shows a hypsochromic shift to 3029-3028 and 3018-3017 cm-1, respectively. Carbon 55-61 complement C3 Homo sapiens 51-54 2698356-2 1989 Fourteen hours after the last insulin injection, the animals had three-fold elevated rates of appearance Ra and of disappearance Rd of glucose in relation to non-diabetic controls; the metabolic clearance rate was reduced, glucose carbon recirculation was slightly elevated, and the % lactate from glucose was not altered. Carbon 231-237 insulin Canis lupus familiaris 30-37 7514599-8 1994 Strains bearing disruption of genes encoding other V-ATPase subunits (VMA1, VMA2, VMA3, and VMA4) fail to grow on media supplemented with 100 mM CaCl2 or 4 mM ZnCl2, media buffered to pH 7.5, or media with a glycerol carbon source. Carbon 217-223 H(+)-transporting V1 sector ATPase subunit A Saccharomyces cerevisiae S288C 70-74 2555279-8 1989 Analysis of the EPR spectra revealed hyperfine splitting constants that indicated the presence of carbon-centered radical spin adducts in both organ tissues from animals exposed to endotoxin for twenty-five minutes. Carbon 98-104 spindlin 1 Homo sapiens 122-126 8040062-0 1994 Synthesis and biological activities of C-3 heterocyclyl carbon-substituted new cephalosporins. Carbon 56-62 complement C3 Homo sapiens 39-42 3223942-2 1988 The irreversible disappearance of lactate carbon from the body (RdL) is commonly calculated from data obtained with a continuous infusion of isotopically labelled lactate tracer. Carbon 42-48 LEO1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 64-67 8148372-1 1994 Heme oxygenase isozymes, HO-1 and HO-2, catalyze the cleavage of heme b (Fe-protoporphyrin-IX) at the alpha-meso carbon bridge to form the antioxidant, biliverdin IX alpha, and the putative cellular messenger, carbon monoxide. Carbon 113-119 heme oxygenase 1 Rattus norvegicus 25-38 3223942-11 1988 We found that RdL can be calculated from the infusion rate and the pyruvate specific radioactivity, multiplied by the fraction of the total carbon flow out of pyruvate that goes to lactate. Carbon 140-146 LEO1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 14-17 3223942-13 1988 Therefore, if almost all of the pyruvate carbon flows back to lactate, then RdL approaches the tracer infusion rate divided by the pyruvate specific radioactivity. Carbon 41-47 LEO1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 76-79 3145192-1 1988 Saccharomyces cerevisiae strains with a disrupted RAS1 gene and with an intact RAS2 gene (ras1- RAS2 strains) grew well on both fermentable and nonfermentable carbon sources. Carbon 159-165 Ras family GTPase RAS1 Saccharomyces cerevisiae S288C 90-94 8082171-4 1994 The level of CYT2 mRNA is not influenced by the presence or absence of oxygen or of heme, but it is subject to carbon-source control. Carbon 111-117 cytochrome c1 heme lyase CYT2 Saccharomyces cerevisiae S288C 13-17 8177217-2 1994 We have demonstrated that the transcriptional co-activator GAL11, which was identified as an auxiliary factor to GAL4 and which is believed to interact with the zinc finger of the trans-activator, positively influences the level of PGK transcription on both fermentable and non-fermentable carbon sources. Carbon 290-296 Gal11p Saccharomyces cerevisiae S288C 59-64 3145192-8 1988 A ras1- yeast strain with a chromosomal RAS2 gene harbouring the three mutations together did not grow at any temperature using non-fermentable carbon sources, but it was able to grow on glucose at 30 degrees C, and not at 37 degrees C. The mutated proteins were much less effective than the wild-type RAS2 protein in the stimulation of adenylate cyclase, but were efficiently expressed in vivo. Carbon 144-150 Ras family GTPase RAS1 Saccharomyces cerevisiae S288C 2-6 17828935-1 1988 Vibration-rotation lines of C(3) have been identified in the circumstellar spectrum of the obscured carbon star IRC+10216. Carbon 100-106 complement C3 Homo sapiens 28-32 8120000-7 1994 Long chain fatty acyl CoAs (> 8 carbons) were able to inhibit radiolabeling of MMSDH. Carbon 35-42 aldehyde dehydrogenase 6 family member A1 Bos taurus 82-87 17828935-3 1988 This high-resolution infrared detection of the pure carbon chain molecule C(3) allows the estimation of the equilibrium C-C bond length, 1.297 angstroms. Carbon 52-58 complement C3 Homo sapiens 74-78 8087890-1 1994 The cif1 mutation of Saccharomyces cerevisiae causes inability to grow on glucose and related fermentable carbon sources. Carbon 106-112 alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1 Saccharomyces cerevisiae S288C 4-8 17828935-3 1988 This high-resolution infrared detection of the pure carbon chain molecule C(3) allows the estimation of the equilibrium C-C bond length, 1.297 angstroms. Carbon 120-121 complement C3 Homo sapiens 74-78 3183521-2 1988 The direct oxidation-dehydrogenation at C-3 is applicable to other cholanoates (hyodeoxycholic, chenodeoxycholic, ursodeoxycholic, deoxycholic, and cholic) when the hydroxyl groups at C-6, C-7, or C-12 are protected. Carbon 40-41 complement C7 Homo sapiens 189-192 8276800-4 1994 The pim1-delta strains are unable to utilize nonfermentable substrates as the sole carbon source and are unable to maintain functional mitochondrial DNA, indicating that the Pim1 protease is required for mitochondrial function. Carbon 83-89 ATP-dependent Lon protease PIM1 Saccharomyces cerevisiae S288C 4-8 7931241-11 1994 In the case of MAO-B inhibition, the 2 and 3 carbon-chain compounds had similar inhibitory potencies but this increased substantially when the chain length was increased to 4 carbons. Carbon 45-51 monoamine oxidase B Homo sapiens 15-20 3049076-2 1988 When dextrose is the carbon source, the steady-state amount of RAS1 mRNA and the rate of RAS1 protein synthesis are reduced in parallel as cells approach the mid-exponential phase of growth. Carbon 21-27 Ras family GTPase RAS1 Saccharomyces cerevisiae S288C 63-67 7931241-11 1994 In the case of MAO-B inhibition, the 2 and 3 carbon-chain compounds had similar inhibitory potencies but this increased substantially when the chain length was increased to 4 carbons. Carbon 175-182 monoamine oxidase B Homo sapiens 15-20 8264631-8 1994 These results are consistent with the existence of an extragenic factor that binds the ADR1c region and represses ADR1 activity and suggest that other factors are responsible for aiding ADR1 in the carbon source regulation of ADH2. Carbon 198-204 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 87-91 8264631-8 1994 These results are consistent with the existence of an extragenic factor that binds the ADR1c region and represses ADR1 activity and suggest that other factors are responsible for aiding ADR1 in the carbon source regulation of ADH2. Carbon 198-204 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 114-118 8264631-8 1994 These results are consistent with the existence of an extragenic factor that binds the ADR1c region and represses ADR1 activity and suggest that other factors are responsible for aiding ADR1 in the carbon source regulation of ADH2. Carbon 198-204 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 114-118 3049076-2 1988 When dextrose is the carbon source, the steady-state amount of RAS1 mRNA and the rate of RAS1 protein synthesis are reduced in parallel as cells approach the mid-exponential phase of growth. Carbon 21-27 Ras family GTPase RAS1 Saccharomyces cerevisiae S288C 89-93 3049076-3 1988 RAS1 mRNA levels and protein synthesis are very low at all stages of growth when ethanol rather than dextrose is provided as the sole carbon source. Carbon 134-140 Ras family GTPase RAS1 Saccharomyces cerevisiae S288C 0-4 2834341-9 1988 When the suppressor allele (crp-201) was transduced into wild-type strains, the recipient became fucose negative and fucose sensitive (with glycerol as the carbon and energy source) because of impaired expression of fucA. Carbon 156-162 catabolite gene activator protein Escherichia coli 28-31 7504601-6 1993 leprae hsp70-reactive individuals responded to C-344. Carbon 47-48 heat shock protein family A (Hsp70) member 4 Homo sapiens 7-12 3271490-4 1988 This study confirms the propensity of short peptides rich in Aib, the prototype of the amino acid residues dialkylated at the alpha carbon, to adopt a 3(10)-helical structure and is expected to help our understanding of the conformational preferences of the membrane-active, channel-forming, ion-transporting peptaibol antibiotics. Carbon 132-138 ANIB1 Homo sapiens 61-64 8243467-6 1993 When dGlc is the unique carbon source, only alpha and beta anomers of dGlc6P were formed. Carbon 24-30 beta glucuronidase Drosophila melanogaster 5-9 8410991-3 1993 SAR studies have demonstrated that the thiopyran ring, the 5-phenylpyridine substituent, and an acidic functional group on a four-carbon C-2 side chain are all required for optimal inhibitor potency. Carbon 130-136 sarcosine dehydrogenase Homo sapiens 0-3 2459075-0 1988 Immunopharmacological activities of chemically synthesized lipid A-subunit analogue GLA-27 combined with muramyl dipeptide via spacers of different carbon chain length. Carbon 148-154 galactosidase alpha Homo sapiens 84-87 8214087-8 1993 Vitamin K deficiency, caused by carbon stripping the serum or treatment of cell cultures with warfarin, resulted in an induction of carboxylase activity and elevated MGP mRNA. Carbon 32-38 matrix Gla protein Rattus norvegicus 166-169 3429448-8 1987 An alignment of P-450(11 beta) and P-450(SCC) to give maximum matching showed four highly conserved regions (C-1, C-2, C-3, and C-4). Carbon 42-43 complement C2 Bos taurus 114-117 18965720-9 1993 The new sample introduction system was successfully tested in both a process analysis- and a flow injection analysis mode for the determination of total inorganic carbon in Waco tap water. Carbon 163-169 nuclear RNA export factor 1 Homo sapiens 178-181 8464059-1 1993 Using phenyl-azide-mediated photocrosslinking, we show that the alpha carbon of amino acid 2 of the helix-turn-helix motif of bacteriophage lambda Cro is within 12 A of the bottom-strand nucleotides at positions 2 and 3 of the DNA half site in the Cro-DNA complex in solution. Carbon 70-76 cro Escherichia virus Lambda 147-150 3429448-8 1987 An alignment of P-450(11 beta) and P-450(SCC) to give maximum matching showed four highly conserved regions (C-1, C-2, C-3, and C-4). Carbon 43-44 complement C2 Bos taurus 114-117 8464059-1 1993 Using phenyl-azide-mediated photocrosslinking, we show that the alpha carbon of amino acid 2 of the helix-turn-helix motif of bacteriophage lambda Cro is within 12 A of the bottom-strand nucleotides at positions 2 and 3 of the DNA half site in the Cro-DNA complex in solution. Carbon 70-76 cro Escherichia virus Lambda 248-251 2824937-5 1987 Study of the functional activity of the induced cells revealed that the rate of superoxide (O-2) production, as assayed by superoxide dismutase-inhibitable ferricytochrome c reduction, was faster in RA treated HL-60 cells than in TTNPB treated cells (0.41 vs. 0.25 nmol. Carbon 16-17 immunoglobulin kappa variable 1D-39 Homo sapiens 92-95 3021640-4 1986 In the orthorhombic single crystal, we observed interaction of the unpaired electron, which is delocalized on the carbons C(3), C(4) and C(5) with one alpha-proton in position 4 and with four nonequivalent beta-protons connected with the carbon atoms C(2) and C(6). Carbon 114-120 complement C3 Homo sapiens 122-126 8431440-8 1993 The average root mean square deviation for alpha-carbon atoms in the central portion (Arg12-Arg18) of the single helix of motilin was determined to be 0.72 A by the Monte Carlo method, compared to 1.3 A determined by an analysis of the 10 best DIANA structures using the same number of constraints between the same atoms. Carbon 49-55 motilin Homo sapiens 122-129 3790504-8 1986 The data support a mechanism in which a single base catalyzes a 1,3-prototrophic shift of hydrogen from C-1 of the substrate to cofactor, followed by exchange from C-2. Carbon 104-105 complement C2 Bos taurus 164-167 8362465-3 1993 Amino acid composition of alpha-elastin obtained from C-13 NMR spectra correlates with the results of sequencing of tropoelastin. Carbon 54-55 elastin Homo sapiens 32-39 3782058-5 1986 Furthermore, although the carbon-13 NMR signals of sphingosine C-1, C-2, C-3, C-4, and C-5 showed significant chemical shift differences between D-erythro and L-threo-sphingosines of lysosphingolipids, it was concluded that the signal position of sphingosine C-3 was the most important for the determination of D-erythro and L-threo configuration in the long chain base moieties of lysosphingolipids. Carbon 26-32 complement C3 Homo sapiens 73-76 3530324-1 1986 The chirality of biologically active S-adenosyl-L-methionine (AdoMet) is S,S, where the designations refer to the sulfur and the alpha-carbon, respectively. Carbon 135-141 methionine adenosyltransferase I, alpha Mus musculus 37-60 1491605-6 1992 In addition to 16:1 and 18:0, these were the PUFA of 18 carbons and longer, except for 22:6n-3. Carbon 56-63 pumilio RNA binding family member 3 Homo sapiens 45-49 3719908-5 1986 The C-C(methyl) bonds are bent so that angles C(10)-C(1)-C(14) and C(13)-C(8)-C(15) are about 123 degrees, while the methyl groups are orientated with one hydrogen from each pointing away from the carbonyl group. Carbon 4-5 chromosome 12 open reading frame 57 Homo sapiens 46-51 1415584-5 1992 The combination of C-ANF-(11-15) and PHO further delayed the appearance of small metabolites, abolished the appearance of NEP metabolites, and markedly prolonged the permanence of intact 125I-ANF-(1-28) in plasma. Carbon 19-20 natriuretic peptide A Rattus norvegicus 21-24 1415584-5 1992 The combination of C-ANF-(11-15) and PHO further delayed the appearance of small metabolites, abolished the appearance of NEP metabolites, and markedly prolonged the permanence of intact 125I-ANF-(1-28) in plasma. Carbon 19-20 membrane metallo-endopeptidase Rattus norvegicus 122-125 1415584-5 1992 The combination of C-ANF-(11-15) and PHO further delayed the appearance of small metabolites, abolished the appearance of NEP metabolites, and markedly prolonged the permanence of intact 125I-ANF-(1-28) in plasma. Carbon 19-20 natriuretic peptide A Rattus norvegicus 192-195 1618766-4 1992 On the basis of these results, replacement of Leu29(B10) by Ala or Ile appears to allow bound CO to rotate from a conformation pointing toward the beta meso carbon of the heme group to the one pointing toward the alpha meso carbon atom, presumably filling the space left by removal of the delta 2 carbon atom of Leu29(B10). Carbon 224-230 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 46-55 1618766-4 1992 On the basis of these results, replacement of Leu29(B10) by Ala or Ile appears to allow bound CO to rotate from a conformation pointing toward the beta meso carbon of the heme group to the one pointing toward the alpha meso carbon atom, presumably filling the space left by removal of the delta 2 carbon atom of Leu29(B10). Carbon 224-230 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 52-55 1618766-4 1992 On the basis of these results, replacement of Leu29(B10) by Ala or Ile appears to allow bound CO to rotate from a conformation pointing toward the beta meso carbon of the heme group to the one pointing toward the alpha meso carbon atom, presumably filling the space left by removal of the delta 2 carbon atom of Leu29(B10). Carbon 224-230 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 46-55 1618766-4 1992 On the basis of these results, replacement of Leu29(B10) by Ala or Ile appears to allow bound CO to rotate from a conformation pointing toward the beta meso carbon of the heme group to the one pointing toward the alpha meso carbon atom, presumably filling the space left by removal of the delta 2 carbon atom of Leu29(B10). Carbon 224-230 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 52-55 3719908-5 1986 The C-C(methyl) bonds are bent so that angles C(10)-C(1)-C(14) and C(13)-C(8)-C(15) are about 123 degrees, while the methyl groups are orientated with one hydrogen from each pointing away from the carbonyl group. Carbon 4-5 homeobox C13 Homo sapiens 67-72 3719908-5 1986 The C-C(methyl) bonds are bent so that angles C(10)-C(1)-C(14) and C(13)-C(8)-C(15) are about 123 degrees, while the methyl groups are orientated with one hydrogen from each pointing away from the carbonyl group. Carbon 4-5 placenta associated 8 Homo sapiens 78-83 3537717-1 1986 There are two yeast enolase genes, designated ENO1 and ENO2, which are expressed differentially in vegetative cells grown on glucose and in cells grown on gluconeogenic carbon sources. Carbon 169-175 phosphopyruvate hydratase ENO2 Saccharomyces cerevisiae S288C 55-59 1599930-1 1992 We have measured the frequency of the carbon-hydrogen stretching mode of the pro-R and pro-S C4-H bonds of NADH in solution and when bound to pig heart lactate (LDH) or mitochondrial malate (mMDH) dehydrogenases. Carbon 38-44 malate dehydrogenase 2, NAD (mitochondrial) Mus musculus 191-195 3537717-5 1986 This fused gene undergoes glucose-dependent induction and is expressed at the same level as the resident ENO2 gene in cells grown on glucose or gluconeogenic carbon sources. Carbon 158-164 phosphopyruvate hydratase ENO2 Saccharomyces cerevisiae S288C 105-109 1388937-3 1992 The relative configurations at C(1), C(10), C(11) and C(12) are 1S*, 10R*, 11R* and 12R*. Carbon 31-32 chromosome 12 open reading frame 57 Homo sapiens 37-42 3754872-1 1986 Methylenetetrahydrofolate reductase commits tetrahydrofolate-bound one carbon units to use in the regeneration of the methyl group of adenosylmethionine (AdoMet) in eucaryotes and its activity is allosterically inhibited by AdoMet. Carbon 71-77 methylenetetrahydrofolate reductase Homo sapiens 0-35 1388937-3 1992 The relative configurations at C(1), C(10), C(11) and C(12) are 1S*, 10R*, 11R* and 12R*. Carbon 31-32 aldo-keto reductase family 1 member C4 Homo sapiens 44-49 1544898-5 1992 The levels of the mRNAs and proteins for both MRP20 and MRP49 were regulated in response to carbon source. Carbon 92-98 mitochondrial 54S ribosomal protein MRP49 Saccharomyces cerevisiae S288C 56-61 3520568-0 1986 Carbon source regulation of RAS1 expression in Saccharomyces cerevisiae and the phenotypes of ras2- cells. Carbon 0-6 Ras family GTPase RAS1 Saccharomyces cerevisiae S288C 28-32 1740442-3 1992 We recently reported that GTP-binding proteins encoded by rab1B (GGCC), rab2 (GGCC), and rab5 (CCSN) are modified by 20-carbon isoprenyl derivatives of [3H]mevalonate when translated in vitro, despite having carboxyl-terminal sequences distinct from the Caa(M/S/L) motif. Carbon 120-126 RAB2A, member RAS oncogene family Homo sapiens 72-76 3520568-2 1986 The amount of RAS1 mRNA is significantly repressed in cultures grown on the nonfermentable carbon sources ethanol and acetate. Carbon 91-97 Ras family GTPase RAS1 Saccharomyces cerevisiae S288C 14-18 4094193-6 1985 The depression of carbon uptake by Kupffer cells can be seen by light microscopy after multiple administrations of CCl4 compared with that of saline and olive oil. Carbon 18-24 chemokine (C-C motif) ligand 4 Mus musculus 115-119 1310062-12 1992 Taken together, these findings indicate that: (1) enhancement of JUN/AP-1 activity in ara-C-treated cells involves a posttranslational modification of JUN/AP-1; and (2) binding of activated JUN/AP-1 to the AP-1 site in the c-jun promoter confers ara-C inducibility of this gene. Carbon 90-91 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 69-73 1310062-12 1992 Taken together, these findings indicate that: (1) enhancement of JUN/AP-1 activity in ara-C-treated cells involves a posttranslational modification of JUN/AP-1; and (2) binding of activated JUN/AP-1 to the AP-1 site in the c-jun promoter confers ara-C inducibility of this gene. Carbon 90-91 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 155-159 1310062-12 1992 Taken together, these findings indicate that: (1) enhancement of JUN/AP-1 activity in ara-C-treated cells involves a posttranslational modification of JUN/AP-1; and (2) binding of activated JUN/AP-1 to the AP-1 site in the c-jun promoter confers ara-C inducibility of this gene. Carbon 90-91 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 155-159 1310062-12 1992 Taken together, these findings indicate that: (1) enhancement of JUN/AP-1 activity in ara-C-treated cells involves a posttranslational modification of JUN/AP-1; and (2) binding of activated JUN/AP-1 to the AP-1 site in the c-jun promoter confers ara-C inducibility of this gene. Carbon 90-91 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 155-159 1310062-12 1992 Taken together, these findings indicate that: (1) enhancement of JUN/AP-1 activity in ara-C-treated cells involves a posttranslational modification of JUN/AP-1; and (2) binding of activated JUN/AP-1 to the AP-1 site in the c-jun promoter confers ara-C inducibility of this gene. Carbon 90-91 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 223-228 4075817-5 1985 Together these findings suggest that esters whose chain length exceeds 4 carbons will be hydrolyzed primarily by BuChE. Carbon 73-80 cholinesterase Oryctolagus cuniculus 113-118 1607360-4 1992 Straight chain saturated fatty acids having more than 6 carbon atoms could induce both the ACDH and HDT activities, and C13-C15 fatty acids caused the greatest induction of both activities. Carbon 56-62 AV641_RS09045 Pseudomonas fragi 91-95 4079383-1 1985 Deoxycorticosterone acetate (DOCA) and 9 alpha-fluorocortisol acetate (9 alpha-F-Cac) can be modified by the introduction of a double bond at carbons 6 and 7 (6-dehydro-derivatives). Carbon 142-149 solute carrier family 25 member 20 Rattus norvegicus 81-84 1480736-3 1992 The HAL DIRS-C was administered weekly to 147 subjects participating in a 12-week, double-blind medication trial with a psychosocial treatment component. Carbon 12-14 histidine ammonia-lyase Homo sapiens 4-7 3928503-4 1985 The TYS cells, which phagocytized carbon particles and antibody-coated SRBC but not latex particles, released lysosomal enzymes and tumoricidal factor into the supernatant. Carbon 34-40 TYS Homo sapiens 4-7 24425334-2 1992 In medium containing different carbon sources: lactose, fructose, sucrose or glucose plus fructose, the growth of a mixed culture (Yop12+Ss2) shows stimulation ofS. Carbon 31-37 butyrophilin like 2 Homo sapiens 137-140 3928628-5 1985 Exposure of the double-labeled thymidylate synthetase-FdUMP-[2-14C,7,9,3",5"-3H]5,10-CH2H4folate complex to the Bratton-Marshall reaction resulted in 16% cleavage of the C-9, N-10 bond with release solely of p-aminobenzoylglutamate, whereas all of the carbon-14-labeled pterin residue remained covalently bound to the protein. Carbon 252-258 complement C9 Homo sapiens 170-173 1840396-8 1991 This result clearly demonstrates that SPS is involved in the regulation of carbon partitioning in the leaves. Carbon 75-81 sucrose-phosphate synthase Solanum lycopersicum 38-41 4074687-1 1985 Carbon-13 NMR longitudinal relaxation time and line-width studies are reported on the coacervate concentration (about 60% water by weight) of singly carbonyl carbon enriched polypentapeptides of elastin: specifically, (L-Val1-L-[1-13C]Pro2-Gly3-L-Val4-Gly5)n and (L-Val1-L-Pro2-Gly3-L-Val4-[1-13C]Gly5)n. On raising the temperature from 10 to 25 degrees C and from 40 to 70 degrees C, carbonyl mobility increases, but over the temperature interval from 25 to 40 degrees C, the mobility decreases. Carbon 149-155 elastin Homo sapiens 195-202 3971900-10 1985 Perfusions of fatty acids of four or more carbons and alcohols of two or more carbons resulted in a 2- to 4-fold increase of both NT and NT(1-8) levels in plasma. Carbon 42-49 neurotensin Rattus norvegicus 130-132 1909736-10 1991 Absorption of the IgA1 and IgG with alum-bound group C polysaccharide completely removed blocking and lytic activity, respectively, indicating that both the blocking IgA1 and the lytic IgG were specific for the group C capsule. Carbon 53-54 immunoglobulin heavy constant alpha 1 Homo sapiens 18-22 1909736-10 1991 Absorption of the IgA1 and IgG with alum-bound group C polysaccharide completely removed blocking and lytic activity, respectively, indicating that both the blocking IgA1 and the lytic IgG were specific for the group C capsule. Carbon 53-54 immunoglobulin heavy constant alpha 1 Homo sapiens 166-170 1909736-15 1991 We conclude that IgA1, when bound to the group C polysaccharide capsule, can block IgG-initiated lysis of group C meningococci through either the classical or the alternative pathway before or after the organism is exposed to IgG, and that blockade is an Fc-independent event. Carbon 47-48 immunoglobulin heavy constant alpha 1 Homo sapiens 17-21 3971900-10 1985 Perfusions of fatty acids of four or more carbons and alcohols of two or more carbons resulted in a 2- to 4-fold increase of both NT and NT(1-8) levels in plasma. Carbon 42-49 neurotensin Rattus norvegicus 137-139 2983185-5 1985 Calculated electron and spin densities indicate that the radical formed by H abstraction from the phenol oxygen does not remain localized on the oxygen, but is primarily a semiquinone aryl radical with significant unpaired spin density on the ring carbon atoms, particularly on C-3 and C-5. Carbon 248-254 complement C3 Homo sapiens 278-281 1903399-7 1991 Gel permeation chromatography of radiolabeled hydrocarbons released from the rac1, rac2, and ralA proteins by reaction with Raney nickel catalyst indicated that unlike p21Hras, which was modified by a 15-carbon moiety, the rac and ralA translation products were modified by 20-carbon isoprenyl groups. Carbon 51-57 Rac family small GTPase 1 Homo sapiens 77-81 1903399-7 1991 Gel permeation chromatography of radiolabeled hydrocarbons released from the rac1, rac2, and ralA proteins by reaction with Raney nickel catalyst indicated that unlike p21Hras, which was modified by a 15-carbon moiety, the rac and ralA translation products were modified by 20-carbon isoprenyl groups. Carbon 51-57 RAS like proto-oncogene A Homo sapiens 93-97 1903399-7 1991 Gel permeation chromatography of radiolabeled hydrocarbons released from the rac1, rac2, and ralA proteins by reaction with Raney nickel catalyst indicated that unlike p21Hras, which was modified by a 15-carbon moiety, the rac and ralA translation products were modified by 20-carbon isoprenyl groups. Carbon 51-57 Rac family small GTPase 1 Homo sapiens 77-80 6431907-0 1984 A carbon-13 NMR comparative study of metal ion substitutions in human carbonic anhydrase I carboxymethylated at active-site histidine-200. Carbon 2-8 carbonic anhydrase 1 Homo sapiens 70-90 1989987-1 1991 Mitochondrial NADP(H)-specific isocitrate dehydrogenase (IDP1) was purified from yeast cells grown with acetate as a carbon source. Carbon 117-123 isocitrate dehydrogenase (NADP(+)) IDP1 Saccharomyces cerevisiae S288C 57-61 1989987-3 1991 Immunochemical levels of IDP1 were found to vary in inverse proportion with those of mitochondrial NAD(H)-specific isocitrate dehydrogenase in cells grown with glucose or with acetate as a carbon source. Carbon 189-195 isocitrate dehydrogenase (NADP(+)) IDP1 Saccharomyces cerevisiae S288C 25-29 6330727-5 1984 Yeast cells carrying the ATP2-lacZ gene fusion on plasmid p beta Z1 are unable to grow on a nonfermentable carbon source. Carbon 107-113 F1F0 ATP synthase subunit beta Saccharomyces cerevisiae S288C 25-29 1989987-7 1991 A haploid yeast strain containing a chromosomal disruption of the IDP1 locus was constructed and found to be capable of growth with glucose but not with other carbon sources, suggesting that IDP1 provides a critical function and may be the primary source of NADPH in yeast mitochondria. Carbon 159-165 isocitrate dehydrogenase (NADP(+)) IDP1 Saccharomyces cerevisiae S288C 66-70 6090312-7 1984 Other enzymes, the lipoxygenases, may instead introduce oxygen at C-5, C-8, C-9, C-12 or C-15: further conversions from, for example, the initially formed 5- or 15-hydroperoxy acids may lead to the leukotrienes. Carbon 66-67 placenta associated 8 Homo sapiens 89-93 1992916-8 1991 Overall, 43.3 +/- 0.99% of ACR were desorbed from the activated carbon. Carbon 64-70 acrosin Canis lupus familiaris 27-30 6234203-3 1984 The rep gene of Escherichia coli was isolated on a 6-kb PvuII fragment of plasmid pLC44-7 DNA from the Clarke-Carbon collection and cloned into pSC101 (to form pHBH8) and pBR322 (to form pHBH30). Carbon 110-116 replication protein Escherichia coli 4-7 1849960-10 1991 The internal half-saturation constant, Ki1/2 mM is: MM fit (C(i) = 6-100 mM, C(o) = 50 mM), 18.0 mM (HCO3-) and 23.8 mM (Cl-); MS fit (C(i) = 6-920 mM, C(o) = 50 mM), 32.0 mM (HCO3-) and 45.1 mM (Cl-). Carbon 60-61 TNF receptor superfamily member 8 Homo sapiens 39-44 1657733-4 1991 The predominant spin adduct detected after ethanol treatment is proposed to be from a carbon-centered, primary alkyl radical, based on gamma-hydrogen hyperfine splitting patterns observed with PBN-d14. Carbon 86-92 spindlin 1 Rattus norvegicus 16-20 6296052-1 1983 The uxaB gene of Escherichia coli, encoding for altronate oxidoreductase involved in the hexuronate degradative pathway, was isolated on a ColE1-uxaB hybrid plasmid from the Clarke and Carbon bank. Carbon 185-191 oxidoreductase Escherichia coli 58-72 2046877-1 1991 Differential pulse voltammetry with carbon fibre electrodes was used to study the effect of central administration of neurotensin on the extracellular level of 3,4-dihydroxyphenylacetic acid (DOPAC) in the nucleus accumbens and the striatum in anaesthetised rats. Carbon 36-42 neurotensin Rattus norvegicus 118-129 2170047-5 1990 We present results indicating that the carboxyl group as well as the four hydroxyl groups at C-2, C-7, C-24 and C-27 of OA are important for activity. Carbon 98-99 complement component 2 (within H-2S) Mus musculus 93-96 2118902-3 1990 The dual specificity considered here is typified by the oxygenation of arachidonic acid by the reticulocyte lipoxygenase: two chiral products are formed (12S- and 15S-hydroperoxides, ratio approximately 1:9) via hydrogen abstraction from two separate methylene groups (C-10 and C-13). Carbon 269-270 linoleate 9S-lipoxygenase-4 Glycine max 108-120 7151798-3 1982 Immunochemical titration experiments with rabbit antiserum against the purified peroxisomal catalase from alkane-grown C. tropicalis indicated that the remarkable variation in the enzyme activity level on different carbon sources was ascribable to a corresponding change in the amount of the enzyme protein. Carbon 215-221 AT695_RS10915 Staphylococcus aureus 92-100 2176750-1 1990 The effect of ferricytochrome c and methemoglobin on the model phospholipid membrane structure has been investigated using fluorescent probes: 1-anilinonaphthalene-8-sulphonate, 4-dimethylaminochalcone and 3-methoxybenzanthrone. Carbon 8-9 hemoglobin subunit gamma 2 Homo sapiens 36-49 7151798-6 1982 With the use of the cell-free translation system, it was indicated that the significant change in the amount of catalase protein on different carbon sources nearly paralleled that in the activity of the mRNA encoding the enzyme. Carbon 142-148 AT695_RS10915 Staphylococcus aureus 112-120 2166694-6 1990 One of them at least, the elastin receptor was shown to be linked through a G-protein-phospholipase C-IP3 mediated relay to the regulation of intracellular calcium. Carbon 100-101 elastin Homo sapiens 26-33 7161187-5 1982 One of the hydroxyl groups (presumably at C-19) forms a hemiketal ring with the keto group at C-15, and another (at either C-21 or C-23) forms a hemiester with a malonic acid moiety. Carbon 42-43 placenta associated 8 Homo sapiens 94-98 2177114-11 1990 The mechanism of suppressed mesangial uptake of carbon particles may be explained by change of the charge barrier of the glomerular capillary walls and the expansion of the subendothelial space observed after Cox. Carbon 48-54 cytochrome c oxidase subunit 4I1 Mus musculus 209-212 6289902-1 1982 Crude extracts from cells of a Streptomyces strain isolated from a palm-grove soil and grown on different carbon sources showed a constitutive glucokinase. Carbon 106-112 glucokinase Homo sapiens 143-154 2196565-2 1990 A null mutation within the GAL11 locus causes defects in mating, growth on nonfermentable carbon sources, and sporulation of gal11 homozygotes. Carbon 90-96 Gal11p Saccharomyces cerevisiae S288C 27-32 2235835-1 1990 Fatty-acid synthase is an enzyme complex responsible for the synthesis of the carbon chain of fatty acids. Carbon 78-84 fatty acid synthase Homo sapiens 0-19 7093200-4 1982 In addition, PB-1-1 catalyzed oxygen transfer to the p-methyl group of the sulfide substrates to yield the (ethylthio)benzyl alcohol with a turnover of 6.8 min-1, corresponding to a sulfur:carbon oxygenation partition ratio of 6:1. Carbon 189-195 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 Rattus norvegicus 13-19 2160452-4 1990 The resulting protein, Ub-(S-aminoethyl)C48, is equivalent to a wild type ubiquitin except for the substitution of a sulfur atom at the gamma carbon of Lys48. Carbon 142-148 CDK5 regulatory subunit associated protein 2 Homo sapiens 40-43 7042198-1 1982 The selection of Norit RBX-1-activated carbon granules for blood detoxification by haemoadsorption is outlined. Carbon 39-45 ring-box 1 Homo sapiens 23-28 33780054-0 2021 Low-Spin and High-Spin Perferryl Intermediates in Non-Heme Iron Catalyzed Oxidations of Aliphatic C-H Groups. Carbon 64-65 spindlin 1 Homo sapiens 4-8 33780054-0 2021 Low-Spin and High-Spin Perferryl Intermediates in Non-Heme Iron Catalyzed Oxidations of Aliphatic C-H Groups. Carbon 64-65 spindlin 1 Homo sapiens 18-22 6119109-11 1981 The 13C incorporation data indicate that carbons 1, 2, 3, and 4, but not 5, of glutamate serve as the four-carbon donor for the carboxamide carbon, C-5, C-4, and C-3, respectively, of the pyrazole ring of pyrazofurin. Carbon 41-48 complement C3 Homo sapiens 162-165 33773191-13 2021 Molecular docking simulation further evidenced that DS-1 interacts with MDM2 within the p53-binding domain by carbon-hydrogen bond interaction at Lys27, pi-alkyl interactions at Ile37 and Leu30, and van der Waals interactions at Ile75, Val51, Val69, Phe67, Met38, Tyr43, Gly34, and Phe31. Carbon 110-116 mitochondrial ribosomal protein L58 Homo sapiens 52-56 33773191-13 2021 Molecular docking simulation further evidenced that DS-1 interacts with MDM2 within the p53-binding domain by carbon-hydrogen bond interaction at Lys27, pi-alkyl interactions at Ile37 and Leu30, and van der Waals interactions at Ile75, Val51, Val69, Phe67, Met38, Tyr43, Gly34, and Phe31. Carbon 110-116 MDM2 proto-oncogene Homo sapiens 72-76 6119109-11 1981 The 13C incorporation data indicate that carbons 1, 2, 3, and 4, but not 5, of glutamate serve as the four-carbon donor for the carboxamide carbon, C-5, C-4, and C-3, respectively, of the pyrazole ring of pyrazofurin. Carbon 41-47 complement C3 Homo sapiens 162-165 6119109-11 1981 The 13C incorporation data indicate that carbons 1, 2, 3, and 4, but not 5, of glutamate serve as the four-carbon donor for the carboxamide carbon, C-5, C-4, and C-3, respectively, of the pyrazole ring of pyrazofurin. Carbon 107-113 complement C3 Homo sapiens 162-165 7420350-3 1980 (b) Two groups of THC-type cannabinoids which differ only in that the chemical groupings in one of them at C-1, C-2 are situated at C-1, C-6 in the other (but retain their stereochemistry) have almost equivalent psychotropic activity. Carbon 20-21 complement C6 Macaca mulatta 132-140 7381189-1 1980 The carbon adsorption method was used for separating organic matter from large samples of drainage, river and tap water. Carbon 4-10 nuclear RNA export factor 1 Homo sapiens 110-113 33811408-4 2021 This review summarizes the current knowledge about 14-3-3 proteins in plants, including their molecular structure and function, regulatory mechanism, and roles in carbon and nitrogen metabolism and stress responses. Carbon 163-169 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta Homo sapiens 51-57 33587587-2 2021 Hereby, a bimetallic phosphide embedded in a N and P co-doped porous carbon (FeCoP2@NPPC) material was synthesized by using sustainable biomass-derived N- and P-containing carbohydrates and non-noble metal salts as precursors. Carbon 69-75 natriuretic peptide C Homo sapiens 77-88 388072-3 1979 Endocytosis of carrageenan, latex, or carbon particles in vitro induced a prominent rise in intracellular cathepsin B activity. Carbon 38-44 cathepsin B Mus musculus 106-117 34890952-8 2022 This work provided a facile method for the preparation of Fe-based carbon materials with high catalytic ability, low metal leaching and easy recycling, showing a broad prospect for environmental applications. Carbon 67-73 general transcription factor IIE subunit 1 Homo sapiens 58-60 40811-1 1979 Aldehyde reductase from human liver catalyzes the hydrogen transfer from the pro-4R position on the dihydronicotinamide ring of the coenzyme to the re face of the carbonyl carbon atom of the substrate. Carbon 163-169 aldo-keto reductase family 1 member A1 Homo sapiens 0-18 34846150-2 2022 A key reaction is a regio-divergent oxidative phenolic coupling reaction that affords the tricyclic core structure of hasubanan with different substitution patterns on the A-ring, including the all-carbon quaternary stereogenic center at C13, in a single step. Carbon 198-204 homeobox C13 Homo sapiens 238-241 34941270-2 2022 The straight-chain structures with an MCCC (M = metal; C = carbon) connectivity are found for the isoelectronic IrC3-, PtC3, and AuC3+ clusters. Carbon 59-65 nuclear receptor coactivator 4 Homo sapiens 119-123 489163-4 1979 Furthermore, the mutagenicity of the syn- and anti-BP-diolepoxide isomers correlated positively with their documenrences in the ability of each derivative to form a carbonium ion. Carbon 165-174 synemin Homo sapiens 37-40 34953854-2 2022 Here, we report that human microsomal dehydrogenase reductase 9 (DHRS9, also known as SDR9C4 of the short-chain dehydrogenase/reductase superfamily) exhibits a robust oxidative activity toward oxylipins with hydroxyl groups located at carbons C9 and C13 of octadecanoids, C12 and C15 carbons of eicosanoids, and C14 carbon of docosanoids. Carbon 235-242 dehydrogenase/reductase 9 Homo sapiens 65-70 34953854-2 2022 Here, we report that human microsomal dehydrogenase reductase 9 (DHRS9, also known as SDR9C4 of the short-chain dehydrogenase/reductase superfamily) exhibits a robust oxidative activity toward oxylipins with hydroxyl groups located at carbons C9 and C13 of octadecanoids, C12 and C15 carbons of eicosanoids, and C14 carbon of docosanoids. Carbon 235-242 dehydrogenase/reductase 9 Homo sapiens 86-92 34953854-2 2022 Here, we report that human microsomal dehydrogenase reductase 9 (DHRS9, also known as SDR9C4 of the short-chain dehydrogenase/reductase superfamily) exhibits a robust oxidative activity toward oxylipins with hydroxyl groups located at carbons C9 and C13 of octadecanoids, C12 and C15 carbons of eicosanoids, and C14 carbon of docosanoids. Carbon 284-291 dehydrogenase/reductase 9 Homo sapiens 65-70 34953854-2 2022 Here, we report that human microsomal dehydrogenase reductase 9 (DHRS9, also known as SDR9C4 of the short-chain dehydrogenase/reductase superfamily) exhibits a robust oxidative activity toward oxylipins with hydroxyl groups located at carbons C9 and C13 of octadecanoids, C12 and C15 carbons of eicosanoids, and C14 carbon of docosanoids. Carbon 284-291 dehydrogenase/reductase 9 Homo sapiens 86-92 34953854-2 2022 Here, we report that human microsomal dehydrogenase reductase 9 (DHRS9, also known as SDR9C4 of the short-chain dehydrogenase/reductase superfamily) exhibits a robust oxidative activity toward oxylipins with hydroxyl groups located at carbons C9 and C13 of octadecanoids, C12 and C15 carbons of eicosanoids, and C14 carbon of docosanoids. Carbon 316-322 dehydrogenase/reductase 9 Homo sapiens 65-70 34953854-2 2022 Here, we report that human microsomal dehydrogenase reductase 9 (DHRS9, also known as SDR9C4 of the short-chain dehydrogenase/reductase superfamily) exhibits a robust oxidative activity toward oxylipins with hydroxyl groups located at carbons C9 and C13 of octadecanoids, C12 and C15 carbons of eicosanoids, and C14 carbon of docosanoids. Carbon 316-322 dehydrogenase/reductase 9 Homo sapiens 86-92 220130-5 1979 At sufficiently high concentrations, straight-chain alcohols having more than two carbon atoms inhibited the action of secretin or vasoactive intestinal peptide on adenylate cyclase activity, and this and this action was irreversible. Carbon 82-88 secretin Cavia porcellus 119-127 34784552-11 2021 X-Ray, proton, and carbon-ion IRs induced similar immune responses, regulated by the STING-STAT1 axis. Carbon 19-25 signal transducer and activator of transcription 1 Homo sapiens 91-96 486108-5 1979 Synthetic alpha omega-diamines with 3--12 carbon atoms also prevented the increase in ornithine decarboxylase activity induced by serum in these cells. Carbon 42-48 ornithine decarboxylase, structural 1 Mus musculus 86-109 34908056-4 2021 The dynamics are controlled by addition to the carbon-carbon triple bond with the reaction intermediates eventually eliminating a hydrogen atom from the methyl groups of the dimethylacetylene reactant forming 1-methyl-3-methylenecyclopropene (p28). Carbon 47-53 golgi SNAP receptor complex member 1 Homo sapiens 243-246 34908056-4 2021 The dynamics are controlled by addition to the carbon-carbon triple bond with the reaction intermediates eventually eliminating a hydrogen atom from the methyl groups of the dimethylacetylene reactant forming 1-methyl-3-methylenecyclopropene (p28). Carbon 54-60 golgi SNAP receptor complex member 1 Homo sapiens 243-246 34960338-2 2021 A sensitive electrochemical sensor based on a molecularly imprinted polymer-modified carbon electrode for the detection of beta-lactoglobulin was successfully synthesized. Carbon 85-91 beta-lactoglobulin Bos taurus 123-141 423808-2 1979 The value of QO2 is higher on a mixture of n-alkanes (C12--C20) than on individual hydrocarbons whose availability is determined by the length of a hydrocarbon chain: C15 and C16-alkanes are oxidized best of all; C14, C13 and C12-alkanes are oxidized at a lower rate; and alkanes whose chain comprises less than ten carbon atoms are not oxidized at all. Carbon 88-94 placenta associated 8 Homo sapiens 167-170 34590769-5 2021 Subsequently, a ketoreductase ChaE rearranges the carbon skeleton and afford the alpha-pyrone containing pentacyclic intermediate in an NADPH-dependent manner, presumably via a cascade reactions including the reduction of the lactone carbonyl group, Aldol-type reaction, followed by a spontaneous gamma-lactone ring formation, and aromatization. Carbon 50-56 2,4-dienoyl-CoA reductase 1 Homo sapiens 136-141 696875-6 1978 The guanidino carbon of arginine was incorporated by the kidney into urea, creatine GSA, GAA, and guanidinobutyric acid. Carbon 14-20 alpha glucosidase Rattus norvegicus 89-92 203511-2 1978 It is found that cya and crp mutants lose their ability to grow on nucleosides as carbon sources in spite of the preservation of the basal levels of nucleoside catabolizing enzymes, found in cell-free extracts of cya and crp mutants. Carbon 82-88 catabolite gene activator protein Escherichia coli 25-28 34747616-5 2021 Compared to previous reports, CoMn2O4-modified screen-printed carbon electrodes display superior performance for the RXS detection, including a wide linear range (0.01-0.84 muM; 0.84-1130 muM), a low limit of detection (0.002 muM), and a high sensitivity (33.13 muA muM-1 cm-2). Carbon 62-68 PWWP domain containing 3A, DNA repair factor Homo sapiens 266-271 66316-4 1977 Differences in recoveries of the dose from 4-14C and 6-14C demonstrate that ring cleavage of 1 with loss of the C-6 carbon represents a major metabolite route. Carbon 116-122 LOW QUALITY PROTEIN: complement component C6 Oryctolagus cuniculus 112-115 857582-2 1977 The binding of CS2 carbon was studied similarly 3 h after the injection. Carbon 19-25 calsyntenin 2 Rattus norvegicus 15-18 857582-6 1977 All of the neurofilament associated CS2 carbon was bound to protein in control group 3 h after the injection. Carbon 40-46 calsyntenin 2 Rattus norvegicus 36-39 857582-7 1977 The binding of CS2 carbon was 4.7 times less than that of sulphur at the same time. Carbon 20-26 calsyntenin 2 Rattus norvegicus 16-19 319838-1 1977 In Saccharomyces cerevisiae harvested from early exponential growth on glucose-containing media, the specifc activities of proteinases A and B, carboxypeptidase Y, and the inhibitors IA, IB, IC of these three proteinases, respectively, are found to be 10-30% of the specific activities observed in media without glucose, containing acetate as a carbon source; the activities of two aminopeptidases in glucose-grown cells were 30-50% of those in acetate-grown cells. Carbon 345-351 proteinase A Saccharomyces cerevisiae S288C 123-142 976263-3 1976 The alkylation of a histidine residue which is fast and extensive when the alkylation side chain is on the C-3 carbon atom, is dramatically decreased when alkylating side chain is shifted towards rings B and D. These results allow the location of this histidine in the vicinity of ring A and probably on the beta face of the steroid nucleus. Carbon 111-117 complement C3 Homo sapiens 107-110 782788-0 1976 Conformations of the repeat peptides of elastin in solution: an application of proton and carbon-13 magnetic resonance to the determination of polypeptide secondary structure. Carbon 90-96 elastin Homo sapiens 40-47 1052292-3 1976 Furthermore, the possibility of completely regenerating carbon with tap water washing makes the routine use of an artificial kidney based on a cold operating carbon depurator extremely practical. Carbon 56-62 nuclear RNA export factor 1 Homo sapiens 68-71 1052292-3 1976 Furthermore, the possibility of completely regenerating carbon with tap water washing makes the routine use of an artificial kidney based on a cold operating carbon depurator extremely practical. Carbon 158-164 nuclear RNA export factor 1 Homo sapiens 68-71 1176436-3 1975 The specificities of the benzyl alcohol dehydrogenase and the benzaldehyde dehydrogenase for their three respective substrates are independent of the carbon source used for growth, suggesting that a single set of nonspecific enzymes is responsible for the dissimilation of the breakdown products of toluene and m- and p-xylene. Carbon 150-156 benzyl alcohol dehydrogenase Pseudomonas putida 25-53 1176436-3 1975 The specificities of the benzyl alcohol dehydrogenase and the benzaldehyde dehydrogenase for their three respective substrates are independent of the carbon source used for growth, suggesting that a single set of nonspecific enzymes is responsible for the dissimilation of the breakdown products of toluene and m- and p-xylene. Carbon 150-156 benzaldehyde dehydrogenase Pseudomonas putida 62-88 1159785-0 1975 Proton and carbon magnetic resonance studies of the synthetic polypentapeptide of elastin. Carbon 11-17 elastin Homo sapiens 82-89 4474832-1 1974 Long-chain saturated fatty acids (C(13) to C(18)) and fatty alcohols (C(12) to C(18)) were well utilized by three different soil isolates of Cladosporium resinae as the sole carbon and energy sources in static liquid cultures. Carbon 174-180 homeobox C13 Homo sapiens 34-39 4842293-0 1974 Solvent dependence of peptide carbonyl carbon chemical shifts and polypeptide secondary structure: the repeat tetrapeptide of elastin. Carbon 30-36 elastin Homo sapiens 126-133 16658319-4 1973 Radioactive carbon in acetate-2-(14)C and especially pyruvate-3-(14)C is incorporated predominantly into the C-2 of glycolate in both species, but the specific radioactivity is much greater in maize. Carbon 12-18 chalcone synthase C2 Zea mays 109-112 5959145-0 1966 [Evaluation of the dose of over-exposure near high-energy accelerators by means of the C-12 (x,nx) C-11 reaction in body hair]. Carbon 87-88 RNA polymerase III subunit K Homo sapiens 99-103 14337111-0 1965 [INCORPORATION OF THE C14 CARBON OF GLUCOSE INTO RAT DIAPHRAGM LIPIDS IN THE ABSENCE AND PRESENCE OF INSULIN]. Carbon 26-32 anti-Mullerian hormone receptor type 2 Rattus norvegicus 22-25 13186537-0 1954 [Effects of hot carbon gas on dental tissue: its applications in carbanesth technic]. Carbon 16-22 alcohol dehydrogenase iron containing 1 Homo sapiens 12-15 33515963-1 2021 A novel Z-scheme heterojunction C@WS2/g-C3N4 composite was prepared with carbon as a bridge for improving the photocatalytic property. Carbon 73-79 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 32-37 34029365-4 2021 show that like central carbon metabolism, iron metabolism is also closely implicated in autophagy-mediated life extension via the TORC2 activator Ypk1p and the iron regulator Aft1p. Carbon 23-29 DNA-binding transcription factor AFT1 Saccharomyces cerevisiae S288C 175-180 34027944-2 2021 From an organic chemistry perspective, their rigid tricyclic molecular architectures with a fully substituted carbon center at the C3a-position pose a great challenge to synthetic chemists. Carbon 110-116 complement C3 Homo sapiens 131-134 33984024-0 2021 Pbp1, the yeast ortholog of human Ataxin-2, functions in the cell growth on non-fermentable carbon sources. Carbon 92-98 Pbp1p Saccharomyces cerevisiae S288C 0-4 33984024-0 2021 Pbp1, the yeast ortholog of human Ataxin-2, functions in the cell growth on non-fermentable carbon sources. Carbon 92-98 ataxin 2 Homo sapiens 34-42 33984024-4 2021 In this study, we found that Pbp1 has a role in cell growth on the medium containing non-fermentable carbon sources. Carbon 101-107 Pbp1p Saccharomyces cerevisiae S288C 29-33 33881067-3 2021 Herein, a facile one-pot synthesis strategy with the assistance of dual surface protecting agents was developed to fabricate carbon-supported Pd (Pd/C) nanodendrites with high mesoporosity. Carbon 125-131 phosducin Homo sapiens 146-150 33881067-4 2021 The mesoporous spherical Pd/C nanodendrites are built with connected nanoparticles with a small size of several nanometers and coated by simultaneously formed carbon layers. Carbon 159-165 phosducin Homo sapiens 25-29 33881067-6 2021 Benefiting from the mesoporous feature, small size, defect-rich surface and carbon coating, the obtained mesoporous Pd/C nanodendrites exhibit great electrocatalytic performance toward the oxygen reduction reaction (ORR). Carbon 76-82 phosducin Homo sapiens 116-120 33960373-2 2021 They can then spontaneously decompose to truncated oxidised phospholipids composed of aldehyde, carboxyl and hydroxyl species of five to nine carbon atoms chain length, many of which exhibit potent biological activities. Carbon 142-148 tryptophan 2,3-dioxygenase Homo sapiens 38-40 33938057-1 2021 Inspired by the spongy bone structures, three-dimensional (3D) sponge-like carbons with meso-microporous structures are synthesized through one-step electro-reduction of CO 2 in molten carbonate Li 2 CO 3 -Na 2 CO 3 -K 2 CO 3 at 580 C. SPC4-0.5 (spongy porous carbon obtained by electrolysis of CO 2 at 4 A for 0.5 h) is synthesized with the current efficiency of 96.9%. Carbon 75-82 proprotein convertase subtilisin/kexin type 6 Homo sapiens 236-240 33938057-1 2021 Inspired by the spongy bone structures, three-dimensional (3D) sponge-like carbons with meso-microporous structures are synthesized through one-step electro-reduction of CO 2 in molten carbonate Li 2 CO 3 -Na 2 CO 3 -K 2 CO 3 at 580 C. SPC4-0.5 (spongy porous carbon obtained by electrolysis of CO 2 at 4 A for 0.5 h) is synthesized with the current efficiency of 96.9%. Carbon 75-81 proprotein convertase subtilisin/kexin type 6 Homo sapiens 236-240 33888778-2 2021 Alkaline treatment of an HCH mixture in a dehydrochlorination reaction is hampered by the low reactivity of the beta-HCH isomer (HCl elimination unavoidably occurring through syn H-C-C-Cl arrangements). Carbon 26-27 synemin Homo sapiens 175-178 33784082-0 2021 Enhancing Chemo- and Stereoselectivity in C-H Bond Oxygenation with H2O2 by Nonheme High-Spin Iron Catalysts: The Role of Lewis Acid and Multimetal Centers. Carbon 10-11 spindlin 1 Homo sapiens 89-93 33863325-1 2021 BACKGROUND: Serine hydroxymethyltransferase 2 (SHMT2) is a vital metabolic enzyme in one carbon metabolism catalyzing the conversion of serine to glycine, which has been reported to play a crucial role in the progression of tumors. Carbon 89-95 serine hydroxymethyltransferase 2 Homo sapiens 12-45 33863325-1 2021 BACKGROUND: Serine hydroxymethyltransferase 2 (SHMT2) is a vital metabolic enzyme in one carbon metabolism catalyzing the conversion of serine to glycine, which has been reported to play a crucial role in the progression of tumors. Carbon 89-95 serine hydroxymethyltransferase 2 Homo sapiens 47-52 33387714-4 2021 Therefore, we present here the hydrothermal synthesis of samarium vanadate/carbon nanofiber (SmV/CNF) composite for the determination of sulfadiazine (SFZ). Carbon 75-81 NPHS1 adhesion molecule, nephrin Homo sapiens 97-100 33920441-4 2021 As the content of Fe impurities increases, the voltage loss of activated carbon with the Fe impurity concentrations of 1.12 wt.% (AF-1.12) decreases by 37.9% of the original, which is attributable to the reduce of ohmic leakage and diffusion, and the increase in Faradic redox at the electrode/electrolyte interface. Carbon 73-79 ephrin A5 Homo sapiens 130-134 33333458-2 2021 The GOx/AuNPs/Pty assembly was coated on a Prussian blue (PB)-modified screen-printed carbon electrode (SPCE) to produce the GOx/AuNPs/Pty/PB/SPCE biosensor. Carbon 86-92 hydroxyacid oxidase 1 Homo sapiens 4-7 33333458-2 2021 The GOx/AuNPs/Pty assembly was coated on a Prussian blue (PB)-modified screen-printed carbon electrode (SPCE) to produce the GOx/AuNPs/Pty/PB/SPCE biosensor. Carbon 86-92 hydroxyacid oxidase 1 Homo sapiens 125-128 33476699-2 2021 Intersecting these two cycles, 5,10-methylenetetrahydrofolate reductase (MTHFR) directs one-carbon units from the folate to methionine cycle, to be exclusively used for methionine and S-adenosylmethionine (AdoMet) synthesis. Carbon 92-98 methylenetetrahydrofolate reductase Homo sapiens 31-71 33476699-2 2021 Intersecting these two cycles, 5,10-methylenetetrahydrofolate reductase (MTHFR) directs one-carbon units from the folate to methionine cycle, to be exclusively used for methionine and S-adenosylmethionine (AdoMet) synthesis. Carbon 92-98 methylenetetrahydrofolate reductase Homo sapiens 73-78 33502742-1 2021 This study reports an alternative strategy for the expression of a recombinant L-AI from Enterococcus faecium DBFIQ E36 by auto-induction using glucose and glycerol as carbon sources and residual whey lactose as inducer agent. Carbon 168-174 thrombopoietin Mus musculus 79-80 33750110-4 2021 The coexistence of vicinal NPD/NPL entities plays a vital role in attracting S2 molecules and facilitating N-S bond formation apart from the generally accepted C-S bond in S-cPAN, which could explain the extraordinary electrochemical features of S-cPAN among various nitrogen-containing sulfurized polymers. Carbon 160-161 N-acetylneuraminate pyruvate lyase Homo sapiens 31-34 33755594-4 2021 The theoretical results not only uncover the narrowest nanoribbon structures to realize the SSE and other inspiring thermal spin transport features, but also push carbon-based material candidates towards thermoelectric conversion device applications. Carbon 163-169 spindlin 1 Homo sapiens 124-128 34597616-1 2021 The electrochemical performance of dual layer immunosensor has been studied by employing reduced Graphene oxide (rGO) and its nanocomposites with Carbon Nanofibers (CNFs) and Carbon Nanotubes (CNTs) as supporting matrix for the detection of CA125. Carbon 146-152 mucin 16, cell surface associated Homo sapiens 241-246 34597616-1 2021 The electrochemical performance of dual layer immunosensor has been studied by employing reduced Graphene oxide (rGO) and its nanocomposites with Carbon Nanofibers (CNFs) and Carbon Nanotubes (CNTs) as supporting matrix for the detection of CA125. Carbon 175-181 mucin 16, cell surface associated Homo sapiens 241-246 34688186-4 2021 A dispersive-micro solid phase extraction facilitated by magnetic carbon nanotubes (Mag-CNTs/d-microSPE) was developed, optimized, successfully validated, and applied to ten poppy seed tea samples using gas chromatography-mass spectrometry (GC-MS) analysis. Carbon 66-72 myelin associated glycoprotein Homo sapiens 84-87 34480345-3 2021 Using fast-scan cyclic voltammetry at a carbon-fiber microelectrode implanted in the CA1 subfield of the hippocampus, it was shown that none of three different ischemia/reperfusion models could increase spontaneous, transient adenosine release, and more severe models even suppressed this presumably neuroprotective release. Carbon 40-46 carbonic anhydrase 1 Homo sapiens 85-88 33356857-6 2021 Ath1 was found to be located in the periplasm and was essential for growth on trehalose as sole carbon source, while Nth1 on the other hand was important for oxidative stress resistance, an observation which was consistent by the lower survival rate of the NTH1 deletion strain in human macrophages. Carbon 96-102 atonal bHLH transcription factor 1 Homo sapiens 0-4 34232469-11 2021 IL-1beta levels were up-regulated in intermediate plus and bursaplex group, whereas IFN-gamma m RNA expression levels were upregulated in intermediate IBD with Poly I:C group. Carbon 167-168 interferon gamma Gallus gallus 84-93 34755733-2 2021 In this study, when the methyl side group was modified by sequential addition of fluorine substituents and then the perfluorinated carbon chain was extended up to n-C8F17 by adding CF2 fragments, it transpired that the non-radiative energy processes are significantly suppressed in structurally more rigid polyfluorinated beta-diketonate compounds of the series as C-H oscillators are replaced with low-energy C-F oscillators. Carbon 131-137 ATPase H+ transporting accessory protein 1 Homo sapiens 181-184 34940412-4 2021 The results of the MBR-MBfR experiments indicated that a C/N ratio of two was suitable for NH4+-N, NO2--N, NO3--N, and chemical oxygen demand (COD) removal in partial nitrification-denitrification (PN-D) and hydrogen autotrophic denitrification for further treatment. Carbon 57-58 translocator protein Homo sapiens 19-22 34845453-5 2021 Unlike previously described immunostimulatory siRNAs, their activity is independent of TLR7/8, but requires the RIG-I/IRF3 pathway that induces a more restricted antiviral response with a lower proinflammatory signature compared with poly(I:C). Carbon 241-243 DExD/H-box helicase 58 Homo sapiens 112-117 34821679-4 2021 In this work, nanostructured mesoporous carbon coupled with glucose oxidase (GOx) increased the direct electron transfer to the electrode surface. Carbon 40-46 hydroxyacid oxidase 1 Homo sapiens 60-75 34821679-4 2021 In this work, nanostructured mesoporous carbon coupled with glucose oxidase (GOx) increased the direct electron transfer to the electrode surface. Carbon 40-46 hydroxyacid oxidase 1 Homo sapiens 77-80 34111633-1 2021 This study describes a versatile, robust and fast sample pre-concentration novel method based on chemical vapour deposition grown iron nanoparticles dispersed hierarchical carbon fiber forest (Fe-ACF/CNF) for the determination of multi-pesticide residue in water samples. Carbon 172-178 NPHS1 adhesion molecule, nephrin Homo sapiens 193-203 34613699-8 2021 Furthermore, the experimental thermogravimetric and O2-TPO results confirmed the significant decrease in carbon deposition on the Ni-Cu alloy catalysts. Carbon 105-111 thyroid peroxidase Homo sapiens 55-58 34628855-3 2021 Herein, we propose a silver-modified carbon nanofiber (CNF@Ag) host with asymmetric sodiophilic features to effectively improve the deposition behavior of Na metal. Carbon 37-43 NPHS1 adhesion molecule, nephrin Homo sapiens 55-58 34607437-5 2021 The structural data validated that there were two active sites of C3G for trapping ACR: at C-6 in the A-ring and C-5" in the B-ring. Carbon 113-114 Rap guanine nucleotide exchange factor 1 Homo sapiens 66-69 34396471-1 2021 To improve the efficiency of aptasensors, a signal amplification strategy by coupling tyrosinase (Tyr)-triggered redox cycling with nanoscale porous carbon (NCZIF) has been proposed. Carbon 149-155 tyrosinase Homo sapiens 86-96 34390190-6 2021 Then the electrolyzer apparatus assembled with Ru-CoOx /NF, just requires the ultra-low voltage of 2.2 and 2.62 V to support the current density of 1000 mA cm-2 in alkaline water and seawater electrolysis, respectively, for hydrogen production, better than that of the commercial Pt/C and RuO2 catalysts. Carbon 283-284 neurofascin Homo sapiens 56-58 34407515-0 2021 Ship in Bottle Synthesis of Yolk-Shell MnS@Hollow Carbon Spheres for Sodium Storage. Carbon 50-56 inositol polyphosphate-5-phosphatase D Homo sapiens 0-4 34407515-0 2021 Ship in Bottle Synthesis of Yolk-Shell MnS@Hollow Carbon Spheres for Sodium Storage. Carbon 50-56 glycophorin E (MNS blood group) Homo sapiens 39-42 34407515-4 2021 The space between the carbon shell and MnS core allows the volume change of MnS without deforming the carbon shell or damaging the solid electrolyte interface film formed on the outer surface. Carbon 22-28 glycophorin E (MNS blood group) Homo sapiens 76-79 34407515-4 2021 The space between the carbon shell and MnS core allows the volume change of MnS without deforming the carbon shell or damaging the solid electrolyte interface film formed on the outer surface. Carbon 102-108 glycophorin E (MNS blood group) Homo sapiens 39-42 34533166-3 2021 The obtained integrated catalyst (3-D CNF@CoP/NC) consists of CoP/NC polyhedra with abundant active sites as the "neurons" and carbon nanofibers as the "axons", and displayed remarkable activity with an overpotential of 64.5 mV and 105.6 mV at 10 mA cm-2 in 0.5 M H2SO4 and 1 M KOH respectively and good stability with negligible current change after 80 h of chronoamperometric measurement or 4000 CV cycles. Carbon 127-133 NPHS1 adhesion molecule, nephrin Homo sapiens 38-41 32916405-2 2021 Herein, a carbon selenide nanofilms modified carbon fiber cloth (CSe2 NF/CC) electrode was obtained via in-situ synthesis to detect nitrite. Carbon 10-16 neurofascin Homo sapiens 70-72 33748605-1 2021 A type of carbon molecular sieve (CMS-3KT) was used as the adsorbent for the CH4 enrichment of a methane/oxygen/nitrogen (CH4/O2/N2) mixture using micro-positive pressure vacuum pressure swing adsorption (~120 kPa). Carbon 10-16 immunoglobulin kappa variable 1D-39 Homo sapiens 122-131 33279288-5 2021 More importantly, 10c possessed improved drug-like properties compared to those of ETR with an increased Fsp3 (Fraction of sp3 carbon atoms) value. Carbon 127-133 NIPA magnesium transporter 1 Homo sapiens 105-109 33652428-4 2021 Theoretical results not only uncover the narrowest nanoribbon structures to realize the SSE and other inspiring thermal spin transport features, but also push carbon-based material candidates towards thermoelectric conversion device applications. Carbon 159-165 spindlin 1 Homo sapiens 120-124 33506818-1 2021 A carbon nanotube/nanofiber (CNT/CNF) composite is applied as a cathode substrate to develop a high-loading polysulfide cathode (8.64 mg cm-2, 68 wt% sulfur). Carbon 2-8 NPHS1 adhesion molecule, nephrin Homo sapiens 33-36 33594203-4 2021 HK2 knockdown and GCK expression rewired central carbon metabolism, stimulated mitochondrial respiration and restored essential metabolic functions of normal hepatocytes such as lipogenesis, VLDL secretion, glycogen storage. Carbon 49-55 glucokinase Homo sapiens 18-21 33540061-9 2021 In summary, nanoparticles carrying poly(I:C) conjugated with an F4/80 antibody promoted liver targeting, and they may represent a suitable alternative to HI for future anti-HBV treatment. Carbon 42-44 adhesion G protein-coupled receptor E1 Mus musculus 64-69 33146575-9 2021 We herein demonstrated that the reaction involves carbon-carbon cleavage catalyzed by the Baeyer-Villiger oxidation (BVO) of a carbonyl compound, the BVO substrate, such as a ketol, by FMO5. Carbon 50-56 flavin containing dimethylaniline monoxygenase 5 Homo sapiens 185-189 33146575-9 2021 We herein demonstrated that the reaction involves carbon-carbon cleavage catalyzed by the Baeyer-Villiger oxidation (BVO) of a carbonyl compound, the BVO substrate, such as a ketol, by FMO5. Carbon 57-63 flavin containing dimethylaniline monoxygenase 5 Homo sapiens 185-189 32710115-4 2021 Both transport steps are catalyzed by OMT1, at the rate of net carbon assimilation. Carbon 63-69 anthranilic acid methyltransferase 1 Zea mays 38-42 33254832-4 2021 The porous carbon materials were characterized by SEM, XRD, Raman and N2 adsorption analysis in system, indicating that Arg-2-900 was promising electrode materials for supercapacitors. Carbon 11-17 arginase 2 Homo sapiens 120-125 33467493-1 2021 A synthetic route for the enantioselective construction of the tetracyclic spiro[indolizidine-1,3"-oxindole] framework present in a large number of oxindole alkaloids, with a cis H-3/H-15 stereochemistry, a functionalized two-carbon substituent at C-15, and an E-ethylidene substituent at C-20, is reported. Carbon 226-232 placenta associated 8 Homo sapiens 248-252 32997967-0 2021 Discarded antibiotic mycelial residues derived nitrogen-doped porous carbon for electrochemical energy storage and simultaneous reduction of antibiotic resistance genes(ARGs). Carbon 69-75 serpin family A member 2 (gene/pseudogene) Homo sapiens 169-173 34433156-1 2021 Nickel disulfide nanoparticles (NiS2NPs)-anchored carbon nanofibers (NiS2NPs@CNF) hybrid mats were fabricated via the sequential process of stabilization and carbonization of electrospun polyacrylonitrile-based fibers followed by hydrothermal growth of NiS2NPs on the porous surface of CNFs. Carbon 50-56 NPHS1 adhesion molecule, nephrin Homo sapiens 77-80 34571785-6 2021 Production of inflammatory cytokines, recruitment of innate immune cells and antigen-specific CD4/CD8 memory T cell at the immunized site had been significantly enhanced by MPL+Poly I:C combination. Carbon 184-185 CD4 antigen Mus musculus 94-97 34571785-7 2021 Moreover, MPL+Poly I:C combination enhanced ovalbumin-specific serum IgG, IgG1, and IgG2c production and proliferative function of CD4 and CD8 T cells after in vitro ovalbumin peptide stimulation. Carbon 21-22 LOC105243590 Mus musculus 74-78 34571785-7 2021 Moreover, MPL+Poly I:C combination enhanced ovalbumin-specific serum IgG, IgG1, and IgG2c production and proliferative function of CD4 and CD8 T cells after in vitro ovalbumin peptide stimulation. Carbon 21-22 CD4 antigen Mus musculus 131-134 33183690-2 2021 Consequently, this study explored the feasibility of using low and high carbon containing alum sludge from two water treatment plants to synthesize zeolite LTA. Carbon 72-78 lymphotoxin alpha Homo sapiens 156-159 33383149-2 2021 We aimed to investigate the proposed protective effect of IL-33 in murine fulminant hepatitis induced by a Toll like receptor 3 (TLR3) viral mimetic, Poly I:C or by Concanavalin-A (ConA). Carbon 157-158 interleukin 33 Mus musculus 58-63 34318701-6 2021 Short-chain acylcarnitines (carbon chain length C2, C3, C4, and C5) and long-chain acylcarnitines (C14, C16, and C18) had the highest performance to indicate LPS response when testing the predictive power of single metabolites using receiver-operator characteristics (ROC) analysis. Carbon 28-34 complement C2 Bos taurus 48-66 32648188-6 2020 The target protein was captured by the Anti-Sam68 antibody that was immobilized on the modified Glassy carbon electrode. Carbon 103-109 KH RNA binding domain containing, signal transduction associated 1 Homo sapiens 44-49 34382330-0 2021 Red Bean Pod Derived Heterostructure Carbon Decorated with Hollow Mixed Transition Metals as a Bifunctional Catalyst in Zn-Air Batteries. Carbon 37-43 brain expressed associated with NEDD4 1 Homo sapiens 4-8 34382330-2 2021 We report a facile method to synthesize heterostructure carbon consisting of graphitic and amorphous carbon derived from the agricultural waste of red bean pods. Carbon 56-62 brain expressed associated with NEDD4 1 Homo sapiens 151-155 32805290-1 2020 Removal behaviors of 152+154Eu, 60Co, and 134Cs radionuclides onto Chitosan-acrylic acid-1-vinyl-2-vinylpyrrolidone/oxidized multi-walled carbon nanotubes (CTS-AA-VP/o-MWCNTs) composite has been investigated by batch adsorption technique. Carbon 138-144 mediator complex subunit 25 Homo sapiens 84-90 34382330-2 2021 We report a facile method to synthesize heterostructure carbon consisting of graphitic and amorphous carbon derived from the agricultural waste of red bean pods. Carbon 101-107 brain expressed associated with NEDD4 1 Homo sapiens 151-155 33200159-2 2020 In the present study, glucose oxidase (GOx) was decorated on N-doped carbon (NC) nanoparticles (NPs) as a biomimetic nanoenzyme (NC@GOx NPs), which could promote starvation therapy enhanced PTT and CDT against tumors. Carbon 69-75 hydroxyacid oxidase 1 Homo sapiens 22-37 34575433-0 2021 Atrial Natriuretic Peptide Antibody-Functionalised, PEGylated Multiwalled Carbon Nanotubes for Targeted Ischemic Stroke Intervention. Carbon 74-80 natriuretic peptide A Rattus norvegicus 0-26 34575433-4 2021 The loading of dexamethasone and decoration of PEGylated multiwalled carbon nanotube with atrial natriuretic peptide (ANP) antibody and fluorescein isothiocyanate for targeting ischemic site in the rat stroke model is presented here. Carbon 69-75 natriuretic peptide A Rattus norvegicus 90-116 33200159-2 2020 In the present study, glucose oxidase (GOx) was decorated on N-doped carbon (NC) nanoparticles (NPs) as a biomimetic nanoenzyme (NC@GOx NPs), which could promote starvation therapy enhanced PTT and CDT against tumors. Carbon 69-75 hydroxyacid oxidase 1 Homo sapiens 39-42 33065111-2 2020 Here we probed the activity of the mouse TET1 (mTET1) and Naegleria gruberi TET (nTET) oxygenases with DNA substrates containing extended derivatives of the 5-methylcytosine carrying linear carbon chains and adjacent unsaturated C-C bonds. Carbon 190-196 tet methylcytosine dioxygenase 1 Mus musculus 41-45 34421310-10 2021 Pathway enrichment analysis indicated that MTHFD2 high expression significantly and positively participated in the pathway of one carbon pool by folate (all P<0.05). Carbon 130-136 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 43-49 34421310-12 2021 Our results assumed that MTHFD2 high expression might play a pivotal role in LGG through positively regulating pathway of one carbon pool by folate. Carbon 126-132 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 25-31 34337952-1 2021 Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) plays an important role in one-carbon metabolism. Carbon 82-88 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 0-41 33065111-2 2020 Here we probed the activity of the mouse TET1 (mTET1) and Naegleria gruberi TET (nTET) oxygenases with DNA substrates containing extended derivatives of the 5-methylcytosine carrying linear carbon chains and adjacent unsaturated C-C bonds. Carbon 190-196 tet methylcytosine dioxygenase 1 Mus musculus 47-52 34337952-1 2021 Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) plays an important role in one-carbon metabolism. Carbon 82-88 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 43-49 33065111-2 2020 Here we probed the activity of the mouse TET1 (mTET1) and Naegleria gruberi TET (nTET) oxygenases with DNA substrates containing extended derivatives of the 5-methylcytosine carrying linear carbon chains and adjacent unsaturated C-C bonds. Carbon 229-230 tet methylcytosine dioxygenase 1 Mus musculus 41-45 34319739-2 2021 While these diterpenoids share a 5/7/6-trans-fused ring system (ABC-ring), the three-carbon substitutions at the C13- and C14-positions on the C-ring and appending oxygen functional groups differ among them, accounting for the disparate biological activities of these natural products. Carbon 85-91 homeobox C13 Homo sapiens 113-116 33065111-2 2020 Here we probed the activity of the mouse TET1 (mTET1) and Naegleria gruberi TET (nTET) oxygenases with DNA substrates containing extended derivatives of the 5-methylcytosine carrying linear carbon chains and adjacent unsaturated C-C bonds. Carbon 229-230 tet methylcytosine dioxygenase 1 Mus musculus 47-52 34323067-2 2021 Cytoplasmic citrate flux, mediated by plasma membrane citrate transporter (SLC13A5), mitochondrial citrate carrier (SLC25A1), and ATP-dependent citrate lyase (ACLY), determines the central carbon source for acetyl-CoA required in DNL. Carbon 189-195 ATP citrate lyase Homo sapiens 130-157 34323067-2 2021 Cytoplasmic citrate flux, mediated by plasma membrane citrate transporter (SLC13A5), mitochondrial citrate carrier (SLC25A1), and ATP-dependent citrate lyase (ACLY), determines the central carbon source for acetyl-CoA required in DNL. Carbon 189-195 ATP citrate lyase Homo sapiens 159-163 33065111-2 2020 Here we probed the activity of the mouse TET1 (mTET1) and Naegleria gruberi TET (nTET) oxygenases with DNA substrates containing extended derivatives of the 5-methylcytosine carrying linear carbon chains and adjacent unsaturated C-C bonds. Carbon 231-232 tet methylcytosine dioxygenase 1 Mus musculus 41-45 33065111-2 2020 Here we probed the activity of the mouse TET1 (mTET1) and Naegleria gruberi TET (nTET) oxygenases with DNA substrates containing extended derivatives of the 5-methylcytosine carrying linear carbon chains and adjacent unsaturated C-C bonds. Carbon 231-232 tet methylcytosine dioxygenase 1 Mus musculus 47-52 34443418-3 2021 In an attempt to optimize the electrode structure, we report on a self-assembly synthesis of silicon nanoparticles@nitrogen-doped reduced graphene oxide/carbon nanofiber (Si@N-doped rGO/CNF) composites as potential high-performance anodes for LIB through electrostatic attraction. Carbon 153-159 NPHS1 adhesion molecule, nephrin Homo sapiens 186-189 33147303-0 2020 Design of Fe,N co-doped multi-walled carbon nanotubes for efficient oxygen reduction. Carbon 37-43 general transcription factor IIE subunit 1 Homo sapiens 10-12 33147303-1 2020 Unique Fe and N co-doped multi-walled carbon nanotubes are designed to efficiently catalyze the oxygen reduction reaction (ORR). Carbon 38-44 general transcription factor IIE subunit 1 Homo sapiens 7-9 33174567-2 2020 Raman and XPS spectroscopy demonstrated that the activity is directly correlated with the defectiveness of the carbon material (GO > CNF-PR24-PS > CNF-PR24-LHT > GP). Carbon 111-117 NPHS1 adhesion molecule, nephrin Homo sapiens 133-136 34370082-9 2021 This performance is one of the best among the AIB graphitic carbon materials reported for chloroaluminate anions storage performance. Carbon 60-66 ANIB1 Homo sapiens 46-49 34340715-0 2021 miR221 regulates cell migration by targeting annexin a1 expression in human mesothelial MeT-5A cells neoplastic-like transformed by multi-walled carbon nanotube. Carbon 145-151 annexin A1 Homo sapiens 45-55 32717518-5 2020 Moreover, the ratio of chemical oxygen demand to total nitrogen (C/N) was identified as an effective regulator for the distribution of C14-HSL and 3-oxo-C14-HSL. Carbon 65-66 lipase E, hormone sensitive type Homo sapiens 139-142 34105981-14 2021 Znf1 transcription factor has been implicated in utilization of different carbon sources, including glucose, the most abundant sugar on earth, and non-fermentable substrates, as a key regulator of glycolysis and gluconeogenesis. Carbon 74-80 DNA-binding domain containing protein Saccharomyces cerevisiae S288C 0-4 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 61-67 solute carrier family 2 member 2 Homo sapiens 224-229 34232631-6 2021 Pearson"s correlation coefficient test showed that elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs), and metals (Ca, Co, and V) were negatively correlated to the dysregulated proteins (INSR, IRS-1, AKT, FOXO1, GLUT2, and GLUT4). Carbon 69-71 solute carrier family 2 member 2 Homo sapiens 224-229 32666463-11 2020 It is attributed to the carbon dots adsorption film formation, which possessed a significant protective ability to inhibit the corrosion of steel in the presence of SRB. Carbon 24-30 chaperonin containing TCP1 subunit 4 Homo sapiens 165-168 34213354-0 2021 Perchlorinated Triarylmethyl Radical 99% Enriched 13C at the Central Carbon as EPR Spin Probe Highly Sensitive to Molecular Tumbling. Carbon 69-75 spindlin 1 Homo sapiens 83-87 32818265-6 2020 Environmental monitoring and CCAM showed a much higher level of elemental carbon exposure in CBPs, which was associated with higher wall area and lower lumen area with no change in total airway area for either airway generation. Carbon 74-80 sushi repeat containing protein X-linked 2 Homo sapiens 93-97 34132274-1 2021 Transformation of triple helicene (TH) to double helicene (DH) with adjacent stereogenic carbon atoms and axial stereogenicity was achieved by the unexpected conjugate addition to the central aromatic ring of TH-1. Carbon 89-95 negative elongation factor complex member C/D Homo sapiens 209-213 34125520-4 2021 In the related reaction of LnacnacY(PhNCH2PPh2)2 with (Ph3P)2PdI(Ph), the P-C bond cleavage following with a N-C bond formation was observed. Carbon 76-77 relaxin 2 Homo sapiens 36-48 32979613-7 2020 The sandwich ELISA effectively detected an increased IFN-alpha production in chicken macrophage cells stimulated by polyinosinic:polycytidylic acid (poly I:C), and its minimum detectable level was about 25 pg/mL. Carbon 156-157 interferon Gallus gallus 53-62 34125520-4 2021 In the related reaction of LnacnacY(PhNCH2PPh2)2 with (Ph3P)2PdI(Ph), the P-C bond cleavage following with a N-C bond formation was observed. Carbon 111-112 relaxin 2 Homo sapiens 36-48 34488320-8 2021 The expression of NSE, MAP2 and beta-tubulin increased significantly in the C, L and CL groups compared to the control group (P<0.001), where the CL group had the highest expression among the groups (7.59+-0.126, 7.87+-0.191, 6.36+-0.420, respectively, (P<0.01)). Carbon 76-77 microtubule associated protein 2 Homo sapiens 23-27 33134695-1 2020 The adsorption mechanism of Cr6+ on biochar prepared from corn stalks (raw carbon) was studied by extracting the organic components (OC) and inorganic components (IC). Carbon 75-81 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 28-31 34109152-4 2021 Herein, a rational geometrical design of hierarchical porous graphene-like bubbles (PGBs) as a cathode host of the Li-S system was prepared by employing magnesium oxide (MgO) nanoparticles as templates for carbonization, potassium hydroxide (KOH) as activation agent, and car tal pitch as a carbon source. Carbon 291-297 transaldolase 1 Homo sapiens 276-279 33077786-5 2020 After 3 days in culture, there is a precocious increase in the frequency of neuronal activity and in the expression of maturation marker KCC2 on carbon films as compared to a commonly used glass surface. Carbon 145-151 solute carrier family 12 member 5 Homo sapiens 137-141 34093806-10 2021 The results disclosed that miR-10b targets were predominantly enriched in some vital biological terms and pivotal signaling pathways associated with tumor progression including cell cycle, FoxO, proteoglycans, central carbon metabolism, p53, Notch, HIF-1, focal adhesion, AMPK, and pancreatic cancer. Carbon 218-224 microRNA 10b Homo sapiens 27-34 34168836-1 2021 We report on the discovery and detailed exploration of the unconventional photo-switching mechanism in metallofullerenes, in which the energy of the photon absorbed by the carbon cage pi-system is transformed to mechanical motion of the endohedral cluster accompanied by accumulation of spin density on the metal atoms. Carbon 172-178 spindlin 1 Homo sapiens 287-291 33240764-3 2020 Herein, a composite of carbon nanofibers coated by Co3S4 nanosheets (denoted as CNF@Co3S4) is successfully synthesized as freestanding sulfur host to optimize the interaction with sulfur species. Carbon 23-29 NPHS1 adhesion molecule, nephrin Homo sapiens 80-83 35302413-10 2022 Poly I:C altered IL-6 and TGF-beta gene expression in aMSCs from both healthy and CKD cats when compared with the same cells in standard culture. Carbon 7-8 interleukin 6 Felis catus 17-21 33041307-0 2021 A highly sensitive label-free aptasensor based on gold nanourchins and carbon nanohorns for the detection of lipocalin-2 (LCN-2). Carbon 71-77 lipocalin 2 Homo sapiens 109-120 35567530-6 2022 CLE2 and CLE3 genes responded to carbon-deficient conditions. Carbon 33-39 CLAVATA3/ESR-related 2 Arabidopsis thaliana 0-4 35550508-0 2022 CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer. Carbon 90-96 cyclin dependent kinase 12 Homo sapiens 0-5 33041307-0 2021 A highly sensitive label-free aptasensor based on gold nanourchins and carbon nanohorns for the detection of lipocalin-2 (LCN-2). Carbon 71-77 lipocalin 2 Homo sapiens 122-127 35144080-8 2022 The results show that carbon residues in the PC fly ash mainly have the shorter and branched aliphatic side chains with lower A(CH2)/A(CH3) value. Carbon 22-28 alien Drosophila melanogaster 128-131 32911934-3 2020 In addition, Pd/C was a practical alternative that enabled ligand-free Fukuyama coupling reactions and was efficiently applied to the key C-C bond-forming step to prepare Canagliflozin and Dapagliflozin, which are diabetic SGLT2 inhibitors of current interest. Carbon 138-139 phosducin Homo sapiens 13-17 32794003-0 2020 An electrochemical biosensor based on multi-wall carbon nanotube-modified screen-printed electrode immobilized by uricase for the detection of salivary uric acid. Carbon 49-55 urate oxidase (pseudogene) Homo sapiens 114-121 35520134-3 2022 A new dual N-doped NCX (NCoNC) electrocatalyst is fabricated as a carbon based catalyst though a facile impregnation of peptone in a precursor and ammonia etching pyrolysis method. Carbon 66-72 T cell leukemia homeobox 2 Homo sapiens 19-22 32799169-8 2020 Therefore, NSP1 of PRRSV-2 inhibited the mRNA transcription of ccn1 and ccn2 by blocking the ERK-AP-1 axis in Poly I:C stimulated pig macrophages. Carbon 117-118 SH2 domain containing 3A Homo sapiens 11-15 35212811-2 2022 SHMT2 plays an important role in the maintenance of one-carbon metabolism. Carbon 56-62 serine hydroxymethyltransferase 2 (mitochondrial) Mus musculus 0-5 32909567-2 2020 Herein, the ternary MoS2/SnO2/CNF (CNF: carbon nanofiber) was designed and assembled by an in situ facile method. Carbon 40-46 NPHS1 adhesion molecule, nephrin Homo sapiens 30-33 35435442-1 2022 Absorbable organic halogens (AOX) are a global parameter which refers to a group of chemical compounds that contain one or more chlorine, bromine or iodine atoms in their molecule and can easily adsorb on activated carbon. Carbon 215-221 acyl-CoA oxidase 1 Homo sapiens 29-32 32909567-2 2020 Herein, the ternary MoS2/SnO2/CNF (CNF: carbon nanofiber) was designed and assembled by an in situ facile method. Carbon 40-46 NPHS1 adhesion molecule, nephrin Homo sapiens 35-38 32663377-3 2020 Carbon-coated Na 3 V 2 (PO 4 )F 3 @MWCNT (multi-walled carbon nanotube) samples were fabricated by a hydrothermal-assisted sol-gel method and the electrochemical performances were evaluated at three different temperatures (25, 45, and 55 C). Carbon 0-6 forkhead box L2 Homo sapiens 14-33 35249365-8 2022 Results of proteome analysis of control and DKK1-knockdown human pulmonary artery endothelial cells identified a significantly differentially expressed protein, SHMT2 (serine hydroxymethyltransferase 2), a key metabolic enzyme in one-carbon metabolism, as a novel DKK1 target. Carbon 234-240 serine hydroxymethyltransferase 2 Homo sapiens 161-166 35249365-8 2022 Results of proteome analysis of control and DKK1-knockdown human pulmonary artery endothelial cells identified a significantly differentially expressed protein, SHMT2 (serine hydroxymethyltransferase 2), a key metabolic enzyme in one-carbon metabolism, as a novel DKK1 target. Carbon 234-240 serine hydroxymethyltransferase 2 Homo sapiens 168-201 32663377-3 2020 Carbon-coated Na 3 V 2 (PO 4 )F 3 @MWCNT (multi-walled carbon nanotube) samples were fabricated by a hydrothermal-assisted sol-gel method and the electrochemical performances were evaluated at three different temperatures (25, 45, and 55 C). Carbon 56-62 forkhead box L2 Homo sapiens 14-33 32723868-6 2020 Metabolic tracing studies revealed glucose was required for insulin to stimulate pathways providing carbon substrate, NADPH, and glycerol 3"-phosphate for lipid synthesis and storage. Carbon 100-106 Insulin-like receptor Drosophila melanogaster 60-67 35124880-10 2022 The hydrolysing capacity of the strain towards cellulosic material was assessed for two paper types and the highest activity (2.6+-0.05 U/mL) was found with filter paper as the sole carbon source. Carbon 182-188 thrombopoietin Mus musculus 138-140 35101834-1 2022 A label-free electrochemical immunosensor was constructed for cancer antigen 125 (CA125) detection based on multiple-enlargement means of layer-by-layer (LBL) assembly of ordered mesoporous carbon (CMK-3), gold nanoparticles (Au NPs) and MgAl layered double hydroxides containing ferrocenecarboxylic acid (Fc@MgAl-LDH). Carbon 190-196 mucin 16, cell surface associated Homo sapiens 82-87 35380441-0 2022 Spin-Forbidden Carbon-Carbon Bond Formation in Vibrationally Excited alpha-CO. Carbon 15-21 spindlin 1 Homo sapiens 0-4 33042141-7 2020 High mortality after low dose LPS challenge in Gate-16 -/- Gabarap -/- mice primed with poly(I:C) or polymicrobial sepsis was ameliorated by compound GBP2 deficiency. Carbon 95-97 guanylate binding protein 2 Mus musculus 150-154 35380441-0 2022 Spin-Forbidden Carbon-Carbon Bond Formation in Vibrationally Excited alpha-CO. Carbon 22-28 spindlin 1 Homo sapiens 0-4 32691933-4 2020 By using calcium imaging to monitor signal transduction in sensory neurons expressing the mouse aldehyde OR, Olfr2, we found that the spatial position of the C7 and C8 carbon atoms of octanal, in relation to its -CHO group, determines whether an aliphatic aldehyde functions as an agonist, partial agonist or antagonist. Carbon 168-174 olfactory receptor family 6 subfamily A member 2 Mus musculus 109-114 35464230-2 2022 Through optimizing the TE-G/KMnO4 ratio in the redox reaction between carbon and KMnO4, flower-like MnO2/G microspheres (MnO2/G-10) are obtained with 83.2% MnO2 and 16.8% residual graphene. Carbon 70-76 BUD31 homolog Homo sapiens 126-130 35382861-9 2022 A fraction of PPFIA4 localizes to mitochondria and interacts with MTHFD2, a key enzyme for one-carbon metabolism. Carbon 95-101 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 Mus musculus 14-20 32533225-0 2020 An amperometric biosensor based on poly(L-aspartic acid), nanodiamond particles, carbon nanofiber, and ascorbate oxidase-modified glassy carbon electrode for the determination of L-ascorbic acid. Carbon 137-143 acyl-CoA oxidase 1 Homo sapiens 103-120 35089338-0 2022 The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis. Carbon 104-110 syntaxin of plants 61 Arabidopsis thaliana 25-30 32417651-0 2020 Biodegradable Poly(gamma-glutamic acid)@glucose oxidase@carbon dot nanoparticles for simultaneous multimodal imaging and synergetic cancer therapy. Carbon 56-62 hydroxyacid oxidase 1 Homo sapiens 40-55 35089338-4 2022 Here, we report that the Arabidopsis thaliana trans-Golgi network/early endosome (TGN/EE) localized SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein SYP61 interacts with the transmembrane ubiquitin ligase ATL31, a key regulator of resistance to disrupted carbon (C)/nitrogen/(N)-nutrient conditions. Carbon 292-298 syntaxin of plants 61 Arabidopsis thaliana 186-191 35234919-0 2022 Concerted action: SYP61 and ATL31 cooperatively regulate the carbon/nitrogen nutrient response in Arabidopsis. Carbon 61-67 syntaxin of plants 61 Arabidopsis thaliana 18-23 35227382-1 2022 Carbon dots without heteroatoms-doping and surface modifications were designed to be a novel chemosensing strategy on the quantitative detection of uric acid (UA) with the aid of uricase-induced enzymatic reaction and Fenton reaction. Carbon 0-6 urate oxidase (pseudogene) Homo sapiens 179-186 32701170-3 2020 My laboratory has focused on the regulation of plant lipid metabolism and, as part of this work, we identified diacylglycerol acyltransferase (DGAT) as important at regulating carbon flux during oil accumulation. Carbon 176-182 diacylglycerol O-acyltransferase 1A Glycine max 111-141 35085720-6 2022 In biodistribution study in mice bearing S180 tumor, Tc-2 (1-cyclopentadienyl-5-(2-nitro-1H-imidazol-1-yl)-pentan-1-one tricarbonyl 99mTc complex), which has intermediate carbon chain, is better due to the more complex factors. Carbon 171-177 transcobalamin 2 Mus musculus 53-57 35335782-0 2022 Surface Transformation of Spin-on-Carbon Film via Forming Carbon Iron Complex for Remarkably Enhanced Polishing Rate. Carbon 34-40 spindlin 1 Homo sapiens 26-30 32701170-3 2020 My laboratory has focused on the regulation of plant lipid metabolism and, as part of this work, we identified diacylglycerol acyltransferase (DGAT) as important at regulating carbon flux during oil accumulation. Carbon 176-182 diacylglycerol O-acyltransferase 1A Glycine max 143-147 32951289-4 2020 Glycine-N-methyltransferase (GNMT) is a critical enzyme in one-carbon metabolism that serves to regulate methylation and remethylation reactions. Carbon 63-69 glycine N-methyltransferase Mus musculus 0-27 35335782-1 2022 To scale down semiconductor devices to a size less than the design rule of 10 nm, lithography using a carbon polymer hard-mask was applied, e.g., spin-on-carbon (SOC) film. Carbon 154-160 spindlin 1 Homo sapiens 146-150 32951289-4 2020 Glycine-N-methyltransferase (GNMT) is a critical enzyme in one-carbon metabolism that serves to regulate methylation and remethylation reactions. Carbon 63-69 glycine N-methyltransferase Mus musculus 29-33 35258180-4 2022 With the deepening of pollution, the proportion of secondary organic carbon (SOC) in PM1 and PM2.5 increased by 22.0% and 12.5%, respectively. Carbon 69-75 transmembrane protein 11 Homo sapiens 85-88 32498890-4 2020 Due to the stronger interaction between DNA and Ru (bpy)2 (dppz)2+, the quenched fluorescence of carbon dots was recovered with DNA added. Carbon 97-103 basic charge Y-linked 2 Homo sapiens 48-57 35258180-5 2022 SOC tended to accumulate in small particles, whereas the proportion of primary organic carbon (POC) and elemental carbon (EC) in PM1 decreased by 15.4% and 6.6%, and the POC and EC in PM2.5 decreased by 8.2% and 4.3%, respectively. Carbon 87-93 transmembrane protein 11 Homo sapiens 129-132 35258180-5 2022 SOC tended to accumulate in small particles, whereas the proportion of primary organic carbon (POC) and elemental carbon (EC) in PM1 decreased by 15.4% and 6.6%, and the POC and EC in PM2.5 decreased by 8.2% and 4.3%, respectively. Carbon 114-120 transmembrane protein 11 Homo sapiens 129-132 35258180-5 2022 SOC tended to accumulate in small particles, whereas the proportion of primary organic carbon (POC) and elemental carbon (EC) in PM1 decreased by 15.4% and 6.6%, and the POC and EC in PM2.5 decreased by 8.2% and 4.3%, respectively. Carbon 122-124 transmembrane protein 11 Homo sapiens 129-132 32878129-7 2020 Finally, the detection results of a carbon fiber laminate with artificial delamination through ultrasonic phased array C-scan acquired from Olympus OmniScan MX2 and this proposed algorithm are compared, which showing that this proposed algorithm performs well in defect shape presentation and location calculation. Carbon 36-42 MX dynamin like GTPase 2 Homo sapiens 157-160 35080865-3 2022 Herein, the MnS@MXene@CNF (MMC, CNFs means carbon nanofibers) electrode has been prepared by electrospinning and a subsequent high-temperature annealing process. Carbon 43-49 NPHS1 adhesion molecule, nephrin Homo sapiens 22-25 35061399-4 2022 Here, we report a low-cost approach to massively producing multiwalled carbon nanotubes (MWCNTs) via a combination process of vapor-liquid-solid (VLS) and solid-liquid-solid (SLS) where cotton decomposed into carbon-containing gases and amorphous carbons that then dissolved into Fe nanoparticles, forming Fe/Fe3C-encapsulated MWCNTs. Carbon 71-77 general transcription factor IIE subunit 1 Homo sapiens 280-282 35061399-4 2022 Here, we report a low-cost approach to massively producing multiwalled carbon nanotubes (MWCNTs) via a combination process of vapor-liquid-solid (VLS) and solid-liquid-solid (SLS) where cotton decomposed into carbon-containing gases and amorphous carbons that then dissolved into Fe nanoparticles, forming Fe/Fe3C-encapsulated MWCNTs. Carbon 71-77 general transcription factor IIE subunit 1 Homo sapiens 306-308 32761338-9 2020 RESULTS: Co-treatment with Q, C, H and their combination promoted Schwann cell differentiation, increased CNTF secretion, up-regulated the protein and mRNA expressions of myelin, and increased the number and length of the myelin segments (P<0.01 or P<0.05). Carbon 9-10 ciliary neurotrophic factor Homo sapiens 106-110 35061399-4 2022 Here, we report a low-cost approach to massively producing multiwalled carbon nanotubes (MWCNTs) via a combination process of vapor-liquid-solid (VLS) and solid-liquid-solid (SLS) where cotton decomposed into carbon-containing gases and amorphous carbons that then dissolved into Fe nanoparticles, forming Fe/Fe3C-encapsulated MWCNTs. Carbon 209-215 general transcription factor IIE subunit 1 Homo sapiens 280-282 35061399-4 2022 Here, we report a low-cost approach to massively producing multiwalled carbon nanotubes (MWCNTs) via a combination process of vapor-liquid-solid (VLS) and solid-liquid-solid (SLS) where cotton decomposed into carbon-containing gases and amorphous carbons that then dissolved into Fe nanoparticles, forming Fe/Fe3C-encapsulated MWCNTs. Carbon 209-215 general transcription factor IIE subunit 1 Homo sapiens 306-308 32893576-2 2020 The promoter of phosphoglucose isomerase gene(PGI1) was replaced by that of cytochrome c oxidase subunit VIIa(Cox9)to weaken its expression, aiming to channel more carbon flux into the NADPH-producing pathway. Carbon 164-170 glucose-6-phosphate isomerase Saccharomyces cerevisiae S288C 46-50 35075847-9 2022 The carbon numbers of n-alkane fractions showed a bimodal distribution of C7-C17 and C24-C31, respectively, with C15 being the dominant peak carbon. Carbon 4-10 placenta associated 8 Homo sapiens 113-116 35075847-9 2022 The carbon numbers of n-alkane fractions showed a bimodal distribution of C7-C17 and C24-C31, respectively, with C15 being the dominant peak carbon. Carbon 141-147 placenta associated 8 Homo sapiens 113-116 35020355-2 2022 Herein, we found that Cr6+ (CrO42-) as a smart switch can significantly increase the peroxidase-like (POD-like) activity of silver nanoparticles (Ag NPs), which were anchored efficiently on carbon spheres (Cal-CS/PEG/Ag) using amino-modified poly(ethylene glycol) (PEG) as a bridge. Carbon 190-196 teratocarcinoma-derived growth factor 1 pseudogene 6 Homo sapiens 22-25 32551529-3 2020 Reduction of the precursor particles is achieved in an Ar/H2 (10% H2) atmosphere at 750 C, thereby generating catalytic nanoparticles (c NPs) for carbon nanotube (CNT) growth. Carbon 146-152 ADP-ribosylhydrolase like 1 Homo sapiens 55-60 35145901-7 2021 Demethylating regent decitabine restored RNF135 expression on the cellular level. Carbon 14-20 ring finger protein 135 Homo sapiens 41-47 35127651-7 2021 The most recent researches (since 2017) have been covered and an updated overview about hybrid PCL nanofibers is presented with focus on those including nature-derived additives, e.g., polysaccharides and proteins, and synthetic additives, e.g., inorganic and carbon nanomaterials. Carbon 260-266 PHD finger protein 1 Homo sapiens 95-98 32578639-2 2020 Reaction with CF2ClCOONa yields a single Cs-symmetric Sc3N@C80(CF2) adduct where the CF2 group is inserted into a [6,6]-bond and opens it to 2.3 A between the bridgehead carbon atoms. Carbon 170-176 ATPase H+ transporting accessory protein 1 Homo sapiens 14-17 34979083-3 2022 In humans, CYP24A1 carries out hydroxylation of carbon-23 (C23) or carbon-24 (C24) of the 1alpha,25(OH)2D side chain, eventually resulting in production of either an antagonist of the vitamin-D receptor (C23 pathway) or calcitroic acid (C24 pathway). Carbon 48-54 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 11-18 34979083-3 2022 In humans, CYP24A1 carries out hydroxylation of carbon-23 (C23) or carbon-24 (C24) of the 1alpha,25(OH)2D side chain, eventually resulting in production of either an antagonist of the vitamin-D receptor (C23 pathway) or calcitroic acid (C24 pathway). Carbon 48-54 vitamin D receptor Homo sapiens 184-202 34979083-3 2022 In humans, CYP24A1 carries out hydroxylation of carbon-23 (C23) or carbon-24 (C24) of the 1alpha,25(OH)2D side chain, eventually resulting in production of either an antagonist of the vitamin-D receptor (C23 pathway) or calcitroic acid (C24 pathway). Carbon 67-73 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 11-18 34979083-3 2022 In humans, CYP24A1 carries out hydroxylation of carbon-23 (C23) or carbon-24 (C24) of the 1alpha,25(OH)2D side chain, eventually resulting in production of either an antagonist of the vitamin-D receptor (C23 pathway) or calcitroic acid (C24 pathway). Carbon 67-73 vitamin D receptor Homo sapiens 184-202 32578639-2 2020 Reaction with CF2ClCOONa yields a single Cs-symmetric Sc3N@C80(CF2) adduct where the CF2 group is inserted into a [6,6]-bond and opens it to 2.3 A between the bridgehead carbon atoms. Carbon 170-176 ATPase H+ transporting accessory protein 1 Homo sapiens 63-66 32295803-6 2020 Therefore, our data not only identify a novel role of TKT in regulating lipolysis and obesity but also suggest that limiting glucose-derived carbon into the mitochondria induces lipid catabolism and energy expenditure. Carbon 141-147 transketolase Mus musculus 54-57 35425220-3 2022 The Fe/Co/porous carbon nanoparticles were uniformly dispersed on graphene with high specific surface area and large porosity, which endow high nitrogen doping and many more active sites with better ORR performance than the commercial 20 wt% Pt/C. Carbon 17-23 general transcription factor IIE subunit 1 Homo sapiens 4-6 32676090-0 2020 Loss of Function of Fatty Acid Desaturase 7 in Tomato Enhances Photosynthetic Carbon Fixation Efficiency. Carbon 78-84 omega-3 fatty acid desaturase Solanum lycopersicum 20-43 32676099-6 2020 A previous study has found that the polyadenylated tail [poly(A)] deadenylation complex, called Carbon catabolite repressor 4-Negative on TATA (CCR4-NOT) regulates the expression of spookier (spok), which encodes one of the ecdysteroidogenic enzymes in the fruit fly Drosophila melanogaster. Carbon 96-102 spookier Drosophila melanogaster 192-196 32636744-0 2020 Targeted Antitumor Mechanism of C-PC/CMC-CD55sp Nanospheres in HeLa Cervical Cancer Cells. Carbon 32-34 CD55 molecule (Cromer blood group) Homo sapiens 41-45 32406234-3 2020 In this paper, we report the performance of highly densified carbon nanotubes fiber (HD-CNTf) cross sections called rods (diameter ~69 microm and length ~40 microm) as an ultra-sensitive platform for detection of common neurotransmitters. Carbon 61-67 ciliary neurotrophic factor Homo sapiens 88-92 31758994-3 2020 In this work, the effect of combining carboxyl multi-walled carbon nanotubes (CNTs) and organically modified montmorillonite (MMT) on the morphology and properties of PCL/PLA blend was investigated. Carbon 60-66 PHD finger protein 1 Homo sapiens 167-170 32603158-5 2020 However, 1D systems with linear dispersion at the Fermi energy, such as metallic carbon nanotubes, are an exception since spin pumping is chiral even without interactions. Carbon 81-87 spindlin 1 Homo sapiens 122-126 32341072-5 2020 We find using the CIBN-CRY2 optogenetic dimerization system that the phosphoryl group positioned at carbon 5 of PIP2 is necessary for interaction with ENaC. Carbon 100-106 cryptochrome circadian regulator 2 Homo sapiens 23-27 32317286-5 2020 An hrr25 mutation results in reduced phosphorylation of Puf3 in vivo and a puf3 deletion mutation reverses growth defects of hrr25 mutant cells grown on medium with a nonfermentable carbon source. Carbon 182-188 mRNA-binding protein PUF3 Saccharomyces cerevisiae S288C 75-79 32483148-7 2020 Survival upon nutrient stress or pentose phosphate pathway (PPP) inhibition depends on compensatory NADPH production through the mitochondrial one-carbon metabolism that is severely compromised in CI mutant cells. Carbon 147-153 2,4-dienoyl-CoA reductase 1 Homo sapiens 100-105 32142918-8 2020 Similar to its family member SHMT2, SHMT1 plays a crucial role in folate-dependent serine/glycine inter-conversion in one-carbon metabolism. Carbon 122-128 serine hydroxymethyltransferase 2 Homo sapiens 29-34 32142918-9 2020 In Drosha wild type GC cells, SHMT2 mediates a mitochondrial-carbon metabolic pathway, which is a major pathway of one-carbon metabolism in normal cells and most cancer cells. Carbon 61-67 drosha ribonuclease III Homo sapiens 3-9 32142918-9 2020 In Drosha wild type GC cells, SHMT2 mediates a mitochondrial-carbon metabolic pathway, which is a major pathway of one-carbon metabolism in normal cells and most cancer cells. Carbon 61-67 serine hydroxymethyltransferase 2 Homo sapiens 30-35 32142918-9 2020 In Drosha wild type GC cells, SHMT2 mediates a mitochondrial-carbon metabolic pathway, which is a major pathway of one-carbon metabolism in normal cells and most cancer cells. Carbon 119-125 drosha ribonuclease III Homo sapiens 3-9 32142918-9 2020 In Drosha wild type GC cells, SHMT2 mediates a mitochondrial-carbon metabolic pathway, which is a major pathway of one-carbon metabolism in normal cells and most cancer cells. Carbon 119-125 serine hydroxymethyltransferase 2 Homo sapiens 30-35 32142918-10 2020 However, in Drosha-silenced or Drosha low-expressing GC cells, miR-6778-5p positively regulates SHMT1, instead of SHMT2, thus mediating a compensatory activation of cytoplasmic carbon metabolism that plays an essential role in the maintenance of CSCs in gastric cancer (GCSCs). Carbon 177-183 drosha ribonuclease III Homo sapiens 12-18 32142918-10 2020 However, in Drosha-silenced or Drosha low-expressing GC cells, miR-6778-5p positively regulates SHMT1, instead of SHMT2, thus mediating a compensatory activation of cytoplasmic carbon metabolism that plays an essential role in the maintenance of CSCs in gastric cancer (GCSCs). Carbon 177-183 drosha ribonuclease III Homo sapiens 31-37 32481524-1 2020 Lung adenocarcinoma cells express high levels of ALDH1L1, an enzyme of the one-carbon pathway that catalyzes the conversion of 10-formyltetrahydrofolate into tetrahydrofolate and NAD(P)H. Carbon 79-85 aldehyde dehydrogenase 1 family, member L1 Mus musculus 49-56 32415589-0 2020 A cardiac troponin I photoelectrochemical immunosensor: nitrogen-doped carbon quantum dots-bismuth oxyiodide-flower-like SnO2. Carbon 71-77 troponin I3, cardiac type Homo sapiens 2-20 31972076-4 2020 IFNAR2 binds infectious HCV virions through a direct interaction of its D2 domain with the C-terminal end of apolipoprotein E (apoE) on the viral envelope and facilitates virus entry into host cells. Carbon 25-26 interferon alpha and beta receptor subunit 2 Homo sapiens 0-6 32031718-7 2020 CONCLUSIONS: The preference for bn-1 ion formation is probably due to the higher propensity of the C-terminal peptide bond to be cleaved than other internal bonds. Carbon 0-1 C-C motif chemokine receptor 6 Homo sapiens 32-36 32348673-1 2020 We previously reported the development of an electron-deficient olefin (EDO) ligand, Fro-DO, that promotes the generation of quaternary carbon centers via Ni-catalyzed Csp3-Csp3 cross-coupling with aziridines. Carbon 136-142 dishevelled binding antagonist of beta catenin 1 Homo sapiens 85-91 32149448-1 2020 Linearly fused hydrocarbon nanobelts are a unique type of double-stranded macrocycles that would serve as not only the powerful hosts in supramolecular science but also the templates to grow zig-zag carbon nanotubes with defined diameters. Carbon 20-26 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 195-198 32000026-5 2020 Meanwhile, the significant carbon isotope fractionation was observed in non-sterilized soils, with delta13C of BDE-153 shifting from -29.4% to -26.7% for 1.0 mug/g and to -27.2% for 5.0 mug/g, respectively, whilst not in sterilized soils. Carbon 27-33 homeobox D13 Homo sapiens 111-114 32000026-6 2020 This phenomenon indicated microbial degradation could induce stable carbon isotope fractionation of BDE-153. Carbon 68-74 homeobox D13 Homo sapiens 100-103 32000026-7 2020 The carbon isotope enrichment factor (epsilonc) for BDE-153 microbial degradation was first determined as -7.58%, which could be used to assess the microbial degradation and bioavailability of BDE-153 in wetland soils. Carbon 4-10 homeobox D13 Homo sapiens 52-55 32000026-7 2020 The carbon isotope enrichment factor (epsilonc) for BDE-153 microbial degradation was first determined as -7.58%, which could be used to assess the microbial degradation and bioavailability of BDE-153 in wetland soils. Carbon 4-10 homeobox D13 Homo sapiens 193-196 32319521-4 2020 In Saccharomyces cerevisiae, the deletion of the tps1 encoding gene eliminated the yeast ability to grow on glucose as the sole carbon source. Carbon 128-134 alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1 Saccharomyces cerevisiae S288C 49-53 31856407-0 2020 Formate and potassium ions affect Escherichia coli proton ATPase activity at low pH during mixed carbon fermentation. Carbon 97-103 ATPase Escherichia coli 58-64 32179648-2 2020 The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+ Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell. Carbon 521-527 NAD synthetase 1 Homo sapiens 16-30 32179648-2 2020 The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+ Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell. Carbon 521-527 brain expressed X-linked 3 Homo sapiens 38-42 32179648-2 2020 The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+ Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell. Carbon 521-527 brain expressed X-linked 3 Homo sapiens 171-175 32034861-4 2020 The C-terminal cleavage site of alpha2AP is still unknown. Carbon 4-5 serpin family F member 2 Homo sapiens 32-40 32034861-6 2020 OBJECTIVES: To determine the epitope of TC 3AP and then to localize the C-terminal cleavage site of alpha2AP. Carbon 4-5 serpin family F member 2 Homo sapiens 100-108 32034861-12 2020 CONCLUSIONS: The C-terminal cleavage site of human alpha2AP is located N-terminally from the TC 3AP epitope. Carbon 0-1 serpin family F member 2 Homo sapiens 51-59 32034861-13 2020 As C-terminal cleavage of alpha2AP can occur after multiple residues, different proteases may be responsible for the generation of NPB-alpha2AP. Carbon 0-4 serpin family F member 2 Homo sapiens 26-34 32917632-4 2020 Unexpectedly, we find good thermal contact throughout the nuclear spin bath, virtually independent of the hyperfine coupling strength, which we attribute to effective carbon-carbon interactions mediated by the electronic spin ensemble. Carbon 167-173 spindlin 1 Homo sapiens 66-70 32917632-4 2020 Unexpectedly, we find good thermal contact throughout the nuclear spin bath, virtually independent of the hyperfine coupling strength, which we attribute to effective carbon-carbon interactions mediated by the electronic spin ensemble. Carbon 167-173 spindlin 1 Homo sapiens 221-225 32917632-4 2020 Unexpectedly, we find good thermal contact throughout the nuclear spin bath, virtually independent of the hyperfine coupling strength, which we attribute to effective carbon-carbon interactions mediated by the electronic spin ensemble. Carbon 174-180 spindlin 1 Homo sapiens 66-70 32917632-4 2020 Unexpectedly, we find good thermal contact throughout the nuclear spin bath, virtually independent of the hyperfine coupling strength, which we attribute to effective carbon-carbon interactions mediated by the electronic spin ensemble. Carbon 174-180 spindlin 1 Homo sapiens 221-225 32243173-2 2020 By utilizing Ni(cod)2 as a catalyst precursor, DPEphos as a ligand and 4 A molecular sieves as additives, the dearomatization reaction of beta-naphthols with aryl allylic alcohols proceeded smoothly under mild conditions, affording the desired beta-naphthalenone products bearing a quaternary carbon center in moderate to good yields with excellent linear selectivity. Carbon 293-299 COD2 Homo sapiens 13-21 31855853-2 2020 In this work, three-dimensional (3D) mesoporous gamma-Fe2O3@carbon nanofiber (gamma-Fe2O3@CNF) mat has been synthesized by sol-gel based electrospinning and carbonization successfully. Carbon 60-66 NPHS1 adhesion molecule, nephrin Homo sapiens 90-93 32175544-3 2020 GOx reduces atmospheric O2 to H2O2, causing a cyclic change of cerium ion states, resulting in propagating free radicals in the carbon group in the amino functionalised nanoceria surface. Carbon 128-134 hydroxyacid oxidase 1 Homo sapiens 0-3 32064760-2 2020 Independently of its canonical function as a K-Cl cotransporter, KCC2 regulates the actin cytoskeleton via molecular interactions mediated through its large intracellular C-terminal domain (CTD). Carbon 47-48 solute carrier family 12 member 5 Homo sapiens 65-69 31874322-1 2020 Regression analysis of micropore volume and particle size of powdered activated carbon (PAC) is applied to develop a model to predict the adsorption ratio of a non-polar compound, 2-methylisorneol (2-MIB), onto PACs. Carbon 80-86 MIB E3 ubiquitin protein ligase 1 Homo sapiens 200-203 32041777-3 2020 PQBP1 uses its C-terminal YxxPxxVL motif for binding to the splicing factor thioredoxin like 4A (TXNL4A), but the biological function of this interaction has yet to be elucidated. Carbon 15-16 polyglutamine binding protein 1 Homo sapiens 0-5 32141756-3 2020 Subsequent formation of the six-membered C ring followed by trans-selective installation of the two-carbon unit at C-15 provided rapid access to the key intermediate. Carbon 100-106 placenta associated 8 Homo sapiens 115-119 31896003-2 2020 In this study, we for the first time revealed the role of the air-water interface in enhancing the removal of long-chain perfluoroalkyl carboxylic (PFCAs; CnF2n+1COOH, n >= 7) and perfluoroalkane sulfonic (PFSAs; CnF2n+1SO3H, n >= 6) acids, collectively termed as perfluoroalkyl acids (PFAAs), through combined aeration and adsorption on two kinds of activated carbon (AC). Carbon 361-367 NPHS1 adhesion molecule, nephrin Homo sapiens 155-158 31967944-3 2020 The direct interaction is mediated through the C-terminal tails of both Dyn2 and alpha-actinin 4, and these proteins interact at invasive structures at the plasma membrane. Carbon 47-48 dynamin 2 Homo sapiens 72-76 32087383-5 2020 Na+ had attraction with O atoms (alpha: O6; beta: O6 and O1), with the outflow of electron from C atom to O atom on the C1-O6 bond, which was beneficial to the transformation between chain form and pyran forms. Carbon 96-97 immunoglobulin kappa variable 1D-35 (pseudogene) Homo sapiens 33-59 31907813-0 2020 Characteristics and temporal variations of organic and elemental carbon aerosols in PM1 in Changchun, Northeast China. Carbon 65-71 transmembrane protein 11 Homo sapiens 84-87 31907813-6 2020 Total carbon (TC = EC + OC) constituted 9.11-40.35% of the total PM1 mass, and OC dominated over EC. Carbon 6-12 transmembrane protein 11 Homo sapiens 65-68 31663123-9 2020 Patients with the C(+) IL-33 11877 SNP had lower ST2 serum concentrations than patients with the C(-) 11877 SNP (P = 0.043). Carbon 18-22 ST2 Homo sapiens 49-52 31827253-8 2020 Reduced XRCC6 activity and function may be relevant to ASD etiology due to XRCC6"s role in nonhomologous DNA repair and interactions of the C-terminal SAP domain with DEAF1, a nuclear transcriptional regulator that is important during embryonic development. Carbon 10-11 X-ray repair cross complementing 6 Homo sapiens 75-80 31827253-8 2020 Reduced XRCC6 activity and function may be relevant to ASD etiology due to XRCC6"s role in nonhomologous DNA repair and interactions of the C-terminal SAP domain with DEAF1, a nuclear transcriptional regulator that is important during embryonic development. Carbon 10-11 DEAF1 transcription factor Homo sapiens 167-172 31999292-6 2020 The reaction commences by oxidation of the Pt(ii) complex to give the platinum(iv) species [Pt(bhq)(SMe2)(OAc)2](OAc) followed by C-H activation of benzene to afford the intermediate [PtPh(bhq)(SMe2)(OAc)](OAc) concurrently with the release of HOAc. Carbon 130-131 hypoacusis 2 (autosomal recessive) Homo sapiens 244-248 31799800-5 2020 Raman spectroscopy results point towards strong carbon corrosion after AST in O 2 , even when cycling at low potentials of 0.3-0.7 V vs. the reversible hydrogen electrode, while no corrosion occurred after any load cycling AST in Ar. Carbon 48-54 immunoglobulin kappa variable 1D-39 Homo sapiens 78-81 31799800-7 2020 The results support that the unexpected carbon corrosion occurring at such low potential in the presence of O 2 is due to reactive oxygen species produced between H 2 O 2 and Fe sites via Fenton reactions. Carbon 40-46 immunoglobulin kappa variable 1D-39 Homo sapiens 108-111 31799800-7 2020 The results support that the unexpected carbon corrosion occurring at such low potential in the presence of O 2 is due to reactive oxygen species produced between H 2 O 2 and Fe sites via Fenton reactions. Carbon 40-46 immunoglobulin kappa variable 1D-39 Homo sapiens 167-170 31784309-3 2020 Then, both Luc and Ru(Bpy)2(Mcbpy)2+ were largely co-immobilized onto the PdCu nanocrystals and polyethyleneimine (PEI) modified single-walled carbon nanohorns (SWCNHs-PdCuNCs-PEI) through pi-pi stacking and crosslinking reaction, respectively. Carbon 143-149 basic charge Y-linked 2 Homo sapiens 19-27 31784312-0 2020 Mo2C combined with carbon material nanosphere as an electrochemiluminescence super-enhancer and antibody label for ultrasensitive detection of cardiac troponin I. Carbon 19-25 troponin I3, cardiac type Homo sapiens 143-161 31784312-1 2020 To sensitively detect cardiac troponin I (cTnI), a novel electrochemiluminescence (ECL) immunosensor was constructed on the basis of the core-shell Mo2C combined with carbon material (Mo2C@C) nanosphere as an ECL super-enhancer and a label of secondary antibody (Ab2). Carbon 167-173 troponin I3, cardiac type Homo sapiens 42-46 31812845-0 2020 One-carbon metabolism factor MTHFR variant is associated with saccade latency in Spinocerebellar Ataxia type 2. Carbon 4-10 methylenetetrahydrofolate reductase Homo sapiens 29-34 31812845-0 2020 One-carbon metabolism factor MTHFR variant is associated with saccade latency in Spinocerebellar Ataxia type 2. Carbon 4-10 ataxin 2 Homo sapiens 81-110 32075033-0 2020 Peptide-Carbon Quantum Dots conjugate, Derived from Human Retinoic Acid Receptor Responder Protein 2, against Antibiotic-Resistant Gram Positive and Gram Negative Pathogenic Bacteria. Carbon 8-14 retinoic acid receptor responder 2 Homo sapiens 58-100 32047150-1 2020 Synthesis of ethanol from non-petroleum carbon resources via syngas (a mixture of H2 and CO) is an important but challenging research target. Carbon 40-46 relaxin 2 Homo sapiens 82-91 31944103-0 2020 ZIF-Derived Co9-xNixS8 Nanoparticles Immobilized on N-Doped Carbon as Efficient Catalyst for High-Performance Zinc-air Batteries. Carbon 60-66 phosphoserine phosphatase pseudogene 1 Homo sapiens 12-15 31944103-2 2020 Here, the catalytic activity of a novel catalyst composed of Co9-xNixS8 nanoparticles immobilized on N-doped carbon (Co9-xNixS8/NC) is reported. Carbon 109-115 phosphoserine phosphatase pseudogene 1 Homo sapiens 61-64 31944103-2 2020 Here, the catalytic activity of a novel catalyst composed of Co9-xNixS8 nanoparticles immobilized on N-doped carbon (Co9-xNixS8/NC) is reported. Carbon 109-115 phosphoserine phosphatase pseudogene 1 Homo sapiens 117-120 31944646-3 2020 Herein, spherical metal oxides with high tap density are introduced as carbon-free hosts of sulfur for the first time. Carbon 71-77 nuclear RNA export factor 1 Homo sapiens 41-44 32029834-1 2020 In this article, halloysite nanoclay (Hal) was used as porogen for the synthesis of nitrogen doped porous carbon material with high specific surface area and pore volume. Carbon 106-112 histidine ammonia-lyase Homo sapiens 38-41 32023470-3 2020 Using a ubiquitin C-terminal electrophile, we profile DUBs that function during influenza A virus (IAV) infection and isolate OTUB1 as a key regulator of RIG-I-dependent antiviral responses. Carbon 18-19 DExD/H-box helicase 58 Homo sapiens 154-159 31788929-0 2020 Multi-wall Sn/SnO2@Carbon Hollow Nanofibers Anode Material for High-Rate and Long-Life Lithium-Ion Batteries. Carbon 19-25 strawberry notch homolog 2 Homo sapiens 14-17 31788929-2 2020 In this paper, multi-wall Sn/SnO2@carbon hollow nanofibers evolve from SnO2 nanofibers are designed and pro-gramable synthesized by electrospinning, polypyrrole coating and annealing reduction method. Carbon 34-40 strawberry notch homolog 2 Homo sapiens 29-32 31788929-5 2020 Even after 2000 cycles, the wire-in-double-wall-tube Sn/SnO2@carbon nanofibers exhibit a high specific capacity of 986.3 mAh g-1 (1 A g-1) and still maintains 508.2 mAh g-1 at high current density of 5 A g-1. Carbon 61-67 strawberry notch homolog 2 Homo sapiens 56-59 32211095-3 2020 We profiled the expression alterations of TLR3 and LMP1 within these NPC cell lines in response to poly (I:C) treatment, and found a high correlation between them ws found, suggesting potential involvement of TLR3 in LMP1 signaling. Carbon 71-72 PDZ and LIM domain 7 Homo sapiens 51-55 32211095-3 2020 We profiled the expression alterations of TLR3 and LMP1 within these NPC cell lines in response to poly (I:C) treatment, and found a high correlation between them ws found, suggesting potential involvement of TLR3 in LMP1 signaling. Carbon 71-72 PDZ and LIM domain 7 Homo sapiens 217-221 31862074-3 2020 XPS and FT-IR methods respectively determined the surface functional groups and chemical composition of protonated dissolved organic carbon (HDOC) in a CKDu high-risk zone (HR) of Sri Lanka and in SHA. Carbon 133-139 sorcin Homo sapiens 180-183 31841782-0 2020 Hyperelodiones A-C, monoterpenoid polyprenylated acylphoroglucinols from Hypericum elodeoides, induce cancer cells apoptosis by targeting RXRalpha. Carbon 0-18 retinoid X receptor alpha Homo sapiens 138-146 31841782-8 2020 Thus, hyperelodione C can be considered as a promising lead compound for cancer therapy, which can bind to RXRalpha-LBD and induce HeLa and MCF-7 cell apoptosis. Carbon 6-21 retinoid X receptor alpha Homo sapiens 107-115 31912079-3 2020 Herein, a self-assembled freestanding MoO3/carbon nanofiber (MoO3/CNF) composite membrane is effectively integrated into Li-S batteries as a functional interlayer. Carbon 43-49 NPHS1 adhesion molecule, nephrin Homo sapiens 66-69 31937861-4 2020 Moreover, we have demonstrated that formation of protein corona on the surface of [60]fullerene derivatives is changing the landscape of their activity, tuning the selectivity of obtained carbon nanomaterials towards Fyn A and BTK kinases. Carbon 188-194 Bruton tyrosine kinase Homo sapiens 227-230 31941118-0 2020 Voltammetry at Hexamethyl-P-Terphenyl Poly(Benzimidazolium) (HMT-PMBI)-Coated Glassy Carbon Electrodes: Charge Transport Properties and Detection of Uric and Ascorbic Acid. Carbon 85-91 histamine N-methyltransferase Homo sapiens 61-64 31776190-6 2020 This analysis revealed that SIN3 and SAM-S regulate overlapping pathways, many of which involve one-carbon and central carbon metabolisms. Carbon 100-106 S-adenosylmethionine Synthetase Drosophila melanogaster 37-42 31776190-6 2020 This analysis revealed that SIN3 and SAM-S regulate overlapping pathways, many of which involve one-carbon and central carbon metabolisms. Carbon 119-125 S-adenosylmethionine Synthetase Drosophila melanogaster 37-42 31854945-4 2020 The carbon source metabolic activities of the soil in the ST treatment was the highest, followed by the BC treatment, which was significantly higher than of that in the CK treatment. Carbon 4-10 cytidine/uridine monophosphate kinase 1 Homo sapiens 169-171 31911834-1 2020 Mammalian asparagine endopeptidase (AEP) is a cysteine protease that cleaves its protein substrates on the C-terminal side of asparagine residues. Carbon 107-108 legumain Homo sapiens 10-34 31911834-1 2020 Mammalian asparagine endopeptidase (AEP) is a cysteine protease that cleaves its protein substrates on the C-terminal side of asparagine residues. Carbon 107-108 legumain Homo sapiens 36-39 31740007-2 2020 In this study, a xerogel (RFX) prepared by an optimized conventional sol-gel method and a lignin-based activated carbon (KLP) obtained via chemical activation were used in batch and fixed-bed adsorption experiments. Carbon 113-119 kinesin family member 1B Homo sapiens 121-124 31740007-4 2020 RFX and KLP materials reached the equilibrium adsorption in only 24 h, whereas F400 activated carbon required 48 h. In addition, F400 and KLP adsorbents showed higher equilibrium adsorption capacity values (qe = 0.40 and 0.22 kg/kg, for F400 and KLP, respectively) than that obtained for the xerogel (qe = 0.08 kg/kg). Carbon 94-100 kinesin family member 1B Homo sapiens 138-141 31740007-4 2020 RFX and KLP materials reached the equilibrium adsorption in only 24 h, whereas F400 activated carbon required 48 h. In addition, F400 and KLP adsorbents showed higher equilibrium adsorption capacity values (qe = 0.40 and 0.22 kg/kg, for F400 and KLP, respectively) than that obtained for the xerogel (qe = 0.08 kg/kg). Carbon 94-100 kinesin family member 1B Homo sapiens 138-141 31791492-4 2020 We found that 10 ng/mL to 10 mug/mL ultrafine carbon particles down-regulated the expression of the pluripotency marker SOX2 in hESCs. Carbon 46-52 SRY-box transcription factor 2 Homo sapiens 120-124 31791492-5 2020 Moreover, 1 mug/mL to 10 mug/mL carbon particle treatments disrupted the keratinocyte differentiation, and up-regulated inflammation- and psoriasis-related genes, such as IL-1beta, IL-6, CXCL1, CXCL2, CXCL3, CCL20, CXCL8, and S100A7 and S100A9, respectively. Carbon 32-38 C-X-C motif chemokine ligand 1 Homo sapiens 187-192 31791492-5 2020 Moreover, 1 mug/mL to 10 mug/mL carbon particle treatments disrupted the keratinocyte differentiation, and up-regulated inflammation- and psoriasis-related genes, such as IL-1beta, IL-6, CXCL1, CXCL2, CXCL3, CCL20, CXCL8, and S100A7 and S100A9, respectively. Carbon 32-38 S100 calcium binding protein A9 Homo sapiens 237-243 31773955-1 2019 Carbon-doped GaN (GaN:C) Schottky diodes are prepared by controlling the destruction status of graphene interlayer (GI) on the substrate. Carbon 0-6 glucosidase alpha, neutral C Homo sapiens 18-23 31773955-5 2019 The edge-type threading dislocation density (TDD) and carbon concentration of the GaN:C layer with an embedded 550 C-grown AlN CL on a GI substrate can be significantly reduced to 2.28x10^9 cm^-2 and ~2.88x10^18 cm^-3, respectively. Carbon 54-60 glucosidase alpha, neutral C Homo sapiens 82-87 31773955-9 2019 The PTC characteristic of GaN:C Schottky diodes created by dissociating the GI as a carbon doping source should allow for the future use of high-voltage Schottky diodes in parallel, especially in high temperature environments. Carbon 84-90 glucosidase alpha, neutral C Homo sapiens 26-31 31864392-7 2019 The NAD-dependent transcriptional co-repressor C-terminal Binding Protein (CtBP) was discovered 25 years ago due to its high affinity binding to AdV E1A proteins, however, the role of this interaction in the viral life cycle remains unclear. Carbon 47-48 poly(rC) binding protein 2 Mus musculus 75-79 31710069-2 2019 In this study, we hypothesized that gingival epithelial cell (GEC) adhesion and new tissue attachment to titanium sheets/implants could be promoted by the release of plasmid pLAMA3-CM (encoding a motif of the C-terminal globular domain of LAMA3) from a titanium surface. Carbon 64-65 laminin subunit alpha 3 Homo sapiens 175-180 31694913-4 2019 Using conditional Cep290 mutant mice, in which the C-terminal myosin-tail homology domain of CEP290 is disrupted after the connecting cilium is assembled, we show that this domain is essential for protein confinement between the inner and the outer segments. Carbon 18-19 centrosomal protein 290 Mus musculus 93-99 31295698-2 2019 In this report, lactate dehydrogenase enzyme was appropriately immobilized on the glassy carbon electrode via hydrophobin (HFB1) and graphene oxide nanocomposite. Carbon 89-95 complexin 2 Homo sapiens 123-127 31693217-6 2019 Interestingly, adiponectin treatment also activated AMPK signalling pathway by increasing the phosphorylation of Thr172 in the AMPK alpha subunit; 10muM of compound C, a potent AMPK inhibitor, blocked the protective effects of adiponectin against HG/HL-induced insulin resistance. Carbon 165-166 adiponectin, C1Q and collagen domain containing Rattus norvegicus 15-26 31693217-6 2019 Interestingly, adiponectin treatment also activated AMPK signalling pathway by increasing the phosphorylation of Thr172 in the AMPK alpha subunit; 10muM of compound C, a potent AMPK inhibitor, blocked the protective effects of adiponectin against HG/HL-induced insulin resistance. Carbon 165-166 adiponectin, C1Q and collagen domain containing Rattus norvegicus 227-238 31744922-5 2019 Y. pestis Crp was found to dramatically alter expression of hundreds of genes in a manner dependent upon carbon source and growth state. Carbon 105-111 C-reactive protein, pentraxin-related Mus musculus 10-13 31744922-6 2019 Gel shift assays confirmed direct regulation of the malT and ptsG promoters, and Crp was then linked to Y. pestis growth on maltose as a sole carbon source. Carbon 142-148 C-reactive protein, pentraxin-related Mus musculus 81-84 31638769-3 2019 In such a reasonable design, the surface-controlled direct two-electron electrochemical reaction of the lactate oxidase was determined by cyclic voltammetry (CV) on the carbon nanotube (CNT) modified electrode with favorable high electrochemical active surface area and electronic conductivity. Carbon 169-175 lysyl oxidase Homo sapiens 104-119 34040722-0 2019 Controllable double CF2-insertion into sp2 C-Cu bond using TMSCF3: a facile access to tetrafluoroethylene-bridged structures. Carbon 0-1 ATPase H+ transporting accessory protein 1 Homo sapiens 20-23 31226617-0 2019 Carbon dots-based fluorescent turn off/on sensor for highly selective and sensitive detection of Hg2+ and biothiols. Carbon 0-6 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 97-100 31494508-3 2019 Compared with other reported superoxide dismutase (SOD) electrochemical biosensors, the microsensor presented in our work was featured in the coating of a functionalized ionic liquid polymer (PIL) onto PB nanoparticles (PBNPs) and carbon nanotubes (CNT). Carbon 231-237 serpin family A member 2 (gene/pseudogene) Homo sapiens 192-195 32025087-5 2019 Subsampling of high-resolution ocean biogeochemical process models indicates that some of the differences between float and ship-only estimates of the Southern Ocean carbon flux can be explained by spatial and temporal sampling differences. Carbon 166-172 inositol polyphosphate-5-phosphatase D Homo sapiens 124-128 31348936-3 2019 For targeted delivery of anticancer therapeutics to alphavbeta3-expressing tumor cells, cyclic arginylglycylaspartic acid (RGD) peptide was covalently conjugated to the surface of carboxylic acid-functionalized carbon nanotubes (fCNTs), and the topoisomerase I inhibitor camptothecin (CPT) was encapsulated in the fCNTs (CPT@fCNT-RGD). Carbon 211-217 choline phosphotransferase 1 Homo sapiens 245-289 31672640-2 2019 Alternative mRNA splicing at sites named y and z in the C-terminal part of agrin regulates its interaction with a receptor complex consisting of the agrin-binding protein low-density lipoprotein receptor-related protein 4 (Lrp4) and the tyrosine kinase muscle specific kinase (MuSK). Carbon 56-57 agrin Homo sapiens 75-80 31672640-2 2019 Alternative mRNA splicing at sites named y and z in the C-terminal part of agrin regulates its interaction with a receptor complex consisting of the agrin-binding protein low-density lipoprotein receptor-related protein 4 (Lrp4) and the tyrosine kinase muscle specific kinase (MuSK). Carbon 56-57 agrin Homo sapiens 149-154 31727786-6 2019 We also show that the C-terminal NOI domain of AtRIN4 interacts with the exocyst subunits EXO70B1, EXO70E1, EXO70E2, and EXO70F1. Carbon 22-23 exocyst subunit exo70 family protein E1 Arabidopsis thaliana 99-106 31279203-4 2019 Compared to a control reactor that did not have a membrane separator, the MER achieved significantly higher removals of both dissolved organic carbon (61.5 +- 4.1%) and UV254nm absorbance (63.4 +- 8.4%). Carbon 143-149 G protein-coupled estrogen receptor 1 Homo sapiens 74-77 31672889-5 2019 Crystallography and spectroscopy of the inhibited enzyme are consistent with a metal-centered cobalt radical ~6 angstroms away from the tertiary carbon-centered radical and suggest a means of controlling radical trajectories during MCM catalysis. Carbon 145-151 methylmalonyl-CoA mutase Homo sapiens 232-235 31529764-3 2019 Herein, a 3D conductive carbon nanofiber framework with gradient-distributed ZnO particles as nucleation seeds (G-CNF) to regulate lithium deposition is proposed. Carbon 24-30 NPHS1 adhesion molecule, nephrin Homo sapiens 114-117 31653923-6 2019 We found that TMX2 localizes in the outer nuclear membrane with its N-terminus and C-terminus facing the cytoplasm, where it co-localizes with importin-beta and Ran. Carbon 83-84 thioredoxin related transmembrane protein 2 Homo sapiens 14-18 31542930-7 2019 Density functional theory calculations suggest that the triplet energy varies with the torsion of the aryl acetylide rings relative to the plane defined by the PtC4 unit (where C = the carbon atoms bonded to Pt). Carbon 185-191 pericentriolar material 1 Homo sapiens 160-164 31844685-0 2019 SIX3 and SIX6 interact with GEMININ via C-terminal regions. Carbon 40-41 SIX homeobox 6 Homo sapiens 9-13 31553563-1 2019 The C-terminal domain (CTD) of the largest subunit in eukaryotic RNA polymerase II has a repetitive heptad sequence of Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 which is responsible for recruiting transcriptional regulatory factors. Carbon 4-5 pyrroline-5-carboxylate reductase 1 Homo sapiens 129-133 31832310-2 2019 Here, an MSI frameshift mutation is identified in glioma tumor suppressor candidate region gene 1 (GLTSCR1) that produces two C-terminal-truncated proteins. Carbon 103-104 BRD4 interacting chromatin remodeling complex associated protein Homo sapiens 50-97 31832310-4 2019 Through binding to bromodomains and the phosphorylation-dependent interaction domain of bromodomain protein 4 (BRD4) via the C-terminus, GLTSCR1 blocks oncogenic transcriptional elongation. Carbon 125-126 BRD4 interacting chromatin remodeling complex associated protein Homo sapiens 137-144 31522492-6 2019 The mechanical switching is enabled by strong Au-C covalent bonding between the molecule and the electrodes, which allows the tensile force delivered by the STM piezo to break the molecule at its spiropyran C-O bond. Carbon 49-50 sulfotransferase family 1A member 3 Homo sapiens 157-160 31597378-0 2019 C-terminal Redox Domain of Arabidopsis APR1 is a Non-Canonical Thioredoxin Domain with Glutaredoxin Function. Carbon 0-1 APS reductase 1 Arabidopsis thaliana 39-43 31597378-0 2019 C-terminal Redox Domain of Arabidopsis APR1 is a Non-Canonical Thioredoxin Domain with Glutaredoxin Function. Carbon 0-1 CAX interacting protein 1 Arabidopsis thaliana 87-99 31597378-3 2019 Previous studies have shown that the C-terminal domain of APR acts as a glutathione-dependent reductase. Carbon 37-38 APS reductase 1 Arabidopsis thaliana 58-61 31597378-4 2019 The crystal structure of the C-terminal redox domain of Arabidopsis APR1 (AtAPR1) shows a conserved alpha/beta thioredoxin fold, but not a glutaredoxin fold. Carbon 29-30 APS reductase 1 Arabidopsis thaliana 68-72 31597378-4 2019 The crystal structure of the C-terminal redox domain of Arabidopsis APR1 (AtAPR1) shows a conserved alpha/beta thioredoxin fold, but not a glutaredoxin fold. Carbon 29-30 APS reductase 1 Arabidopsis thaliana 74-80 31204771-3 2019 OBJECTIVE: The aim of this study was to use the natural variations in 13C:12C ratio (carbon-13 isotopic abundance [delta13C]) of n-3 PUFA supplements to assess n-3 PUFA metabolism following DHA or EPA supplementation in humans. Carbon 85-91 pumilio RNA binding family member 3 Homo sapiens 133-137 31411782-3 2019 In certain bacteria, ACLY is used to fix carbon in the reductive tricarboxylic acid cycle. Carbon 41-47 ATP citrate lyase Homo sapiens 21-25 31202315-7 2019 Thus, a nanocomposite (Co3O4@MCF-Chi-GOx) modified glassy carbon electrode (GCE) was fabricated for highly selective detection of glucose using amperometry and cyclic voltammetry. Carbon 58-64 hydroxyacid oxidase 1 Homo sapiens 37-40 31495862-0 2019 How does the mutation in the cap domain of methylcobalamin-dependent methionine synthase influence the photoactivation of the Co-C bond? Carbon 126-127 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 69-88 31495862-4 2019 Unlike the native catalysis, upon photoexcitation, the Co-C bond in MeCbl-bound MetH generates the Co(ii)/CH3 radical pairs (RPs). Carbon 55-56 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 80-84 31557873-3 2019 Intramolecular Heck reaction was utilized to establish the quaternary carbon at C-13, along with the dibenzodihydrofuran functionality. Carbon 70-76 homeobox C13 Homo sapiens 80-84 31616255-2 2019 ELOVL4 is the only family member that catalyzes production of Very Long Chain Saturated Fatty Acids (VLC-SFA) and Very Long Chain Polyunsaturated Fatty Acids (VLC-PUFA) with chain lengths >=28 carbons. Carbon 193-200 pumilio RNA binding family member 3 Homo sapiens 163-167 31240921-4 2019 In contrast, the element-element BDE trend for the 2p homologues is second pi > first pi > sigma for nitrogen and oxygen, and sigma > first pi > second pi for carbon. Carbon 171-177 homeobox D13 Homo sapiens 33-36 31347824-2 2019 Herein, self-standing and binder-free porous N-Co carbon nanofiber (N-Co/CNF) cathodes are prepared for zinc-air batteries (ZABs) by an in situ electrospinning/plasma-etching method. Carbon 50-56 NPHS1 adhesion molecule, nephrin Homo sapiens 73-76 31361119-3 2019 Herein, a novel organic carbon/selenium sulfide (OC/SeS2) composite has been prepared by a one-step in situ method by heating the mixture of commercial polyacrylonitrile (PAN) with selenium sulfide powder in vacuum. Carbon 24-30 secernin 2 Homo sapiens 52-56 31352783-7 2019 Moreover, in polar solvents, the spin is shifted onto the donor substituent and away from the benzylic carbon. Carbon 103-109 spindlin 1 Homo sapiens 33-37 31289360-3 2019 Here we show MTHFD2, a mitochondrial enzyme involved in one-carbon metabolism, contributes to the progression of renal cell carcinoma (RCC) via a novel epitranscriptomic mechanism that involves HIF-2alpha. Carbon 60-66 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 13-19 30986772-0 2019 The gapless energy spectrum and spin-Peierls instability of 1D Heisenberg spin systems in polymeric complexes of transition metals and hypothetical carbon allotropes. Carbon 148-154 spindlin 1 Homo sapiens 74-78 31268713-2 2019 Companion M06-2X but not B3LYP computations reproduce each of these thermodynamic quantities and are in accord with an unusually strong aromatic C-H BDE. Carbon 0-1 homeobox D13 Homo sapiens 149-152 31134803-6 2019 As expected, the GO@CoMoSe2 modified glassy carbon electrode exhibited an excellent electrocatalytic activity toward the sensing of Metol (LOD, 0.009 muM; sensitivity, 2.397 muA muM-1 cm-2). Carbon 44-50 PWWP domain containing 3A, DNA repair factor Homo sapiens 178-183 31115816-5 2019 The sequence of elemental carbon emission for the alcohol blends is (from lowest to highest): IB20 < NB20 < P25 < E13, which is in line with that of peak of particle size distribution and the total particle number emission. Carbon 26-32 tubulin polymerization promoting protein Homo sapiens 114-117 31179470-5 2019 At room temperature, zigzag, armchair, and ring-like organometallic chains formed due to the activation of the C-Br bond to generate a C-Cu-C structure while C-Cl remained intact, illustrating that the C-Cl bond is more stable than C-Br. Carbon 135-136 carbonyl reductase 1 Homo sapiens 111-115 31095373-2 2019 Herein, a "ship in a bottle" design is achieved by impregnating fine transition metal dichalcogenide nanoparticles into defective carbon pores that act as interconnected nanoreactors. Carbon 130-136 inositol polyphosphate-5-phosphatase D Homo sapiens 11-15 31234343-0 2019 Thermal Conductivity and Electrical Resistivity of Melt-Mixed Polypropylene Composites Containing Mixtures of Carbon-Based Fillers. Carbon 110-116 ventricular zone expressed PH domain containing 1 Homo sapiens 51-55 31114894-5 2019 This is the first demonstration of the AlkB proteins to oxidize a methyl group attached to carbon, instead of nitrogen, on a DNA base. Carbon 91-97 alkB homolog 1, histone H2A dioxygenase Homo sapiens 39-43 31216671-0 2019 Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer. Carbon 53-59 methylenetetrahydrofolate reductase Homo sapiens 92-127 31216671-0 2019 Association of Folate and Vitamins Involved in the 1-Carbon Cycle with Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) and Global DNA Methylation in Patients with Colorectal Cancer. Carbon 53-59 methylenetetrahydrofolate reductase Homo sapiens 134-139 33405541-2 2019 Herein, a naturally occurring anticancer drug, amygdalin (synthetic form: Laetrile, a misnomer: vitamin B17), has been modified on the surface of carbon quantum dots, prepared by a hydrothermal method, to probe beta-glucosidase activity. Carbon 146-152 NADH:ubiquinone oxidoreductase subunit B6 Homo sapiens 104-107 31117680-3 2019 Here, we describe a rational design of nonnoble metal-embedding and nitrogen-containing carbon nanofiber (M-CNF) catalysts. Carbon 88-94 NPHS1 adhesion molecule, nephrin Homo sapiens 108-111 31142841-1 2019 Serine hydroxymethyltransferase 2 (SHMT2) regulates one-carbon transfer reactions that are essential for amino acid and nucleotide metabolism, and uses pyridoxal-5"-phosphate (PLP) as a cofactor. Carbon 56-62 serine hydroxymethyltransferase 2 Homo sapiens 0-33 31142841-1 2019 Serine hydroxymethyltransferase 2 (SHMT2) regulates one-carbon transfer reactions that are essential for amino acid and nucleotide metabolism, and uses pyridoxal-5"-phosphate (PLP) as a cofactor. Carbon 56-62 serine hydroxymethyltransferase 2 Homo sapiens 35-40 30978009-6 2019 An isomer of 4, [Re2(CO)8(mu-H)]2(mu-eta2-2,3-mu-eta2-4,5-C4H2O) (5), was obtained from the reaction of 3 with 1 through C-H activation at the 4 position of the furyl ring in 3. Carbon 21-22 G protein-coupled receptor 161 Homo sapiens 17-20 30776721-8 2019 The presence of sp3 carbons due to oxidation of sp2 carbons in GO is further proved by Raman spectroscopy. Carbon 20-27 Sp3 transcription factor Bos taurus 16-19 30776721-8 2019 The presence of sp3 carbons due to oxidation of sp2 carbons in GO is further proved by Raman spectroscopy. Carbon 20-27 Sp2 transcription factor Bos taurus 48-51 30776721-8 2019 The presence of sp3 carbons due to oxidation of sp2 carbons in GO is further proved by Raman spectroscopy. Carbon 52-59 Sp3 transcription factor Bos taurus 16-19 30776721-8 2019 The presence of sp3 carbons due to oxidation of sp2 carbons in GO is further proved by Raman spectroscopy. Carbon 52-59 Sp2 transcription factor Bos taurus 48-51 31058221-3 2019 With oxidase catalysis as a model reaction, experimental studies and theoretical calculations revealed that single-atom nanozymes with carbon nanoframe-confined FeN5 active centers (FeN5 SA/CNF) catalytically behaved like the axial ligand-coordinated heme of cytochrome P450. Carbon 135-141 NPHS1 adhesion molecule, nephrin Homo sapiens 190-193 30915433-4 2019 However, the external NADH dehydrogenases (Nde1/2) and the L-glycerol 3-phosphate shuttle (composed of Gpd1/2 and Gut2), both coupled to the respiratory chain, are known to contribute to cytosolic NAD+ regeneration during growth on non-fermentable carbon sources. Carbon 248-254 NADH-ubiquinone reductase (H(+)-translocating) NDE1 Saccharomyces cerevisiae S288C 43-49 30915433-4 2019 However, the external NADH dehydrogenases (Nde1/2) and the L-glycerol 3-phosphate shuttle (composed of Gpd1/2 and Gut2), both coupled to the respiratory chain, are known to contribute to cytosolic NAD+ regeneration during growth on non-fermentable carbon sources. Carbon 248-254 glycerol-3-phosphate dehydrogenase (NAD(+)) GPD1 Saccharomyces cerevisiae S288C 103-109 30690513-1 2019 Studies have indicated that the carbon starvation response leads to the reprogramming of the transcriptome and metabolome, and many genes, including several important regulators, such as the group S1 basic leucine zipper transcription factors (TFs) bZIP1, bZIP11 and bZIP53, the SNAC-A TF ATAF1, etc., are involved in these physiological processes. Carbon 32-38 G-box binding factor 6 Arabidopsis thaliana 256-262 31027290-0 2019 Diffusive Steel Scrap Melting in Carbon-Saturated Hot Metal-Phenomenological Investigation at the Solid-Liquid Interface. Carbon 33-39 alcohol dehydrogenase iron containing 1 Homo sapiens 50-53 31027290-5 2019 One of the more complex aspects is, among others, the dissolution and melting behaviour of the scrap in carbon-saturated hot metal. Carbon 104-110 alcohol dehydrogenase iron containing 1 Homo sapiens 121-124 31011151-10 2019 Moreover, Mx1 and its related proinflamatory genes (Mx2, Il1b, and Tnf) were also up-regulated in poly I:C-treated mice. Carbon 105-106 MX dynamin-like GTPase 1 Mus musculus 10-13 30942201-1 2019 This report demonstrates that changing the position of the carbon-metal bond in a polypyridyl cyclopalladated complex, i.e. going from PdL1 (N^N^C^N) to PdL2 (N^N^N^C), dramatically influences the photodynamic properties of the complex in cancer cells. Carbon 59-65 programmed cell death 1 ligand 2 Homo sapiens 153-157 31105808-2 2019 The previous PolyI:C studies mainly focused on anti-tumor evaluation at cell level and anti-tumor mechanism involved in MyD88-independent pathway. Carbon 19-20 myeloid differentiation primary response gene 88 Mus musculus 120-125 30606912-0 2019 An Ultrasensitive Electrochemical DNA Biosensor Based on Carboxylated Multi-walled Carbon Nanotube/Molybdenum Disulfide Composites for KRAS Gene Detection. Carbon 83-89 KRAS proto-oncogene, GTPase Homo sapiens 135-139 30606912-1 2019 In this paper, an ultrasensitive electrochemical biosensor based on carboxylated multi-walled carbon nanotube/molybdenum disulfide composites (MWCNTs-COOH/MoS2) for the detection of KRAS gene is described. Carbon 94-100 KRAS proto-oncogene, GTPase Homo sapiens 182-186 30874265-0 2019 Distinct correlation between (CN2)x units and pores: a low-cost method for predesigned wide range control of micropore size of porous carbon. Carbon 134-140 carnosine dipeptidase 2 Homo sapiens 30-33 30874265-1 2019 Flexible control of the micropore size of carbon was achieved in a cost-efficient way by predesigned quantitative correlation between the sizes of extendable (CN2)x nanosized modulators and the generated micropore sizes ranged from 0.2 to 2.3 nm, with effectiveness for boosting the electrochemical performance systematically. Carbon 42-48 carnosine dipeptidase 2 Homo sapiens 159-162 30887976-2 2019 In this research, we have successfully designed and synthesized a hierarchical three-dimensional cobalt sulfide encapsulated carbon nanotube/carbon nanofiber (Co9S8@CNT/CNF) composite, resulting in a high-performance supercapacitor with an unrivalled capacitance of 1580 F g-1 at a current density of 1 A g-1. Carbon 125-131 NPHS1 adhesion molecule, nephrin Homo sapiens 169-172 30922349-0 2019 Role of A2B adenosine receptor-dependent adenosine signaling in multi-walled carbon nanotube-triggered lung fibrosis in mice. Carbon 77-83 adenosine A2b receptor Mus musculus 8-30 30984229-3 2019 Especially WRINKLED1 (WRI1), a well-known key transcription factor involved in the allocation of carbon into oil, has attracted much interest. Carbon 97-103 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 11-20 30984229-3 2019 Especially WRINKLED1 (WRI1), a well-known key transcription factor involved in the allocation of carbon into oil, has attracted much interest. Carbon 97-103 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 22-26 30984737-0 2019 Quantum Behavior of Spin-Orbit Inelastic Scattering of C-Atoms by D2 at Low Energy. Carbon 55-56 spindlin 1 Homo sapiens 20-24 30984737-2 2019 In particular, neutral carbon atoms are known to play a role in interstellar media, either as probes of physical conditions (ground state 3P j spin-orbit populations), or as cooling agent (collisional excitation followed by radiative decay). Carbon 23-29 spindlin 1 Homo sapiens 143-147 30984737-3 2019 This work aims at investigating the spin-orbit excitation of atomic carbon in its ground electronic state due to collisions with molecular deuterium, an isotopic variant of H2, the most abundant molecule in the interstellar medium. Carbon 68-74 spindlin 1 Homo sapiens 36-40 30984737-13 2019 The present data are compared with those obtained for the C-He and C-H2 collisional systems to get new insights into the dynamics of collision induced spin-orbit excitation/relaxation of atomic carbon. Carbon 194-200 spindlin 1 Homo sapiens 151-155 30409585-1 2019 A rapid and sensitive method was developed to determine 131 pesticides in tea by on-line gel permeation chromatography-gas chromatography tandem mass spectrometer (on-line GPC-GC-MS/MS) using graphitized multi-walled carbon nanotubes (MWCNTs) as dispersive solid phase extraction (DSPE) sorbent in sample pretreatment. Carbon 217-223 glycophorin C (Gerbich blood group) Homo sapiens 172-175 30820499-2 2019 We herein report the synthesis of a nanohybrid of ultrasmall NiS2 nanoparticles embedded in porous carbon nanofibers (NiS2NP/p-CNF), which is implemented by an electrospinning process accompanied by further sulfide treatment. Carbon 99-105 NPHS1 adhesion molecule, nephrin Homo sapiens 127-130 30862944-1 2019 Methylenetetrahydrofolate reductase (MTHFR) catalyzes the irreversible conversion of 5,10-methylene-tetrahydrofolate (THF) to 5-methyl-THF, thereby committing one-carbon units to the methionine cycle. Carbon 163-169 methylenetetrahydrofolate reductase Homo sapiens 0-35 30862944-1 2019 Methylenetetrahydrofolate reductase (MTHFR) catalyzes the irreversible conversion of 5,10-methylene-tetrahydrofolate (THF) to 5-methyl-THF, thereby committing one-carbon units to the methionine cycle. Carbon 163-169 methylenetetrahydrofolate reductase Homo sapiens 37-42 30891062-7 2019 Most of the functional categories altered by Gclc overexpression related to metabolism including Drug metabolism, Metabolism of xenobiotics by cytochrome P450, Glutathione metabolism, Starch and sucrose metabolism, Citrate cycle (TCA cycle), One carbon pool by folate. Carbon 246-252 Glutamate-cysteine ligase catalytic subunit Drosophila melanogaster 45-49 30832301-6 2019 Trace element analysis showed that the concentrations of several metal ions differed by factors of >100, and the carbons that most effectively increased AFG1 production contained higher amounts of metal ions. Carbon 113-120 AFG1 like ATPase Homo sapiens 153-157 30832301-8 2019 Furthermore, co-addition of both ions increased AFG1 production stably with the addition of carbon. Carbon 92-98 AFG1 like ATPase Homo sapiens 48-52 30813573-3 2019 This 32CA reaction takes place with total ortho regioselectivity and syn diastereofacial selectivity involving the exocyclic C-C double bond, which is in complete agreement with the experimental outcomes. Carbon 7-8 synemin Homo sapiens 69-72 30813573-3 2019 This 32CA reaction takes place with total ortho regioselectivity and syn diastereofacial selectivity involving the exocyclic C-C double bond, which is in complete agreement with the experimental outcomes. Carbon 125-126 synemin Homo sapiens 69-72 30813573-4 2019 While the C-C bond formation involving the beta-conjugated carbon of alpha-santonin derivative is more favorable than the C-O one, which is responsible for the ortho regioselectivity, the favorable electronic interactions taking place between the oxygen of the nitrile oxide and two axial hydrogen atoms of the alpha-santonin derivative are responsible for the syn diastereofacial selectivity. Carbon 59-65 synemin Homo sapiens 361-364 30838202-0 2019 Effect of Surface and Bulk Properties of Mesoporous Carbons on the Electrochemical Behavior of GOx-Nanocomposites. Carbon 52-59 hydroxyacid oxidase 1 Homo sapiens 95-98 30838202-3 2019 This work aims at studying the effects of surface and bulk properties of carbon nanomaterials with different degrees of graphitization on the electrochemical performances of glucose oxidase (GOx)-nanocomposites produced by immobilizing GOx within a network of carbon nanopaticles. Carbon 73-79 hydroxyacid oxidase 1 Homo sapiens 174-189 30838202-3 2019 This work aims at studying the effects of surface and bulk properties of carbon nanomaterials with different degrees of graphitization on the electrochemical performances of glucose oxidase (GOx)-nanocomposites produced by immobilizing GOx within a network of carbon nanopaticles. Carbon 73-79 hydroxyacid oxidase 1 Homo sapiens 191-194 30838202-3 2019 This work aims at studying the effects of surface and bulk properties of carbon nanomaterials with different degrees of graphitization on the electrochemical performances of glucose oxidase (GOx)-nanocomposites produced by immobilizing GOx within a network of carbon nanopaticles. Carbon 260-266 hydroxyacid oxidase 1 Homo sapiens 174-189 30838202-3 2019 This work aims at studying the effects of surface and bulk properties of carbon nanomaterials with different degrees of graphitization on the electrochemical performances of glucose oxidase (GOx)-nanocomposites produced by immobilizing GOx within a network of carbon nanopaticles. Carbon 260-266 hydroxyacid oxidase 1 Homo sapiens 191-194 30838202-8 2019 Our findings suggest that the electrochemical performance of GOx-nanocomposite material is determined by the combined effects of graphitization index, electrical conductivity and surface chemistry of carbon nanomaterials. Carbon 200-206 hydroxyacid oxidase 1 Homo sapiens 61-64 30755663-8 2019 The PAS-Cys, GAF-Cys and double-Cys attachment each entails distinct configurational constraints of the BV adduct, which can be identified by distinct RR spectroscopic features, i.e. the marker band including the C=C stretching coordinate of the ring A-B methine bridge, which was previously identified as being characteristic for rigid chromophore embedment and high FQY. Carbon 17-18 fibroblast growth factor 9 Homo sapiens 13-16 30471567-8 2019 Moreover, the selectivity of cTnI imprinted glassy carbon electrode (GCE) was investigated for plasma sample analysis in the presence of other nonspecific and specific proteins including cardiac myoglobin (MYG), bovine serum albumin (BSA) and cardiac troponin T (cTnT), respectively. Carbon 51-57 troponin I3, cardiac type Homo sapiens 29-33 30408763-6 2019 ERCO and BRF or BRC had linear relationships during a phase with stable carbon content in the combusted fuel (Phase II) for the two charcoals, which may be generalized to other solid fuels, because this phase is associated to fixed carbon dominating phase which usually exist during solid fuel combustion. Carbon 72-78 BRF1 RNA polymerase III transcription initiation factor subunit Homo sapiens 9-12 30408763-6 2019 ERCO and BRF or BRC had linear relationships during a phase with stable carbon content in the combusted fuel (Phase II) for the two charcoals, which may be generalized to other solid fuels, because this phase is associated to fixed carbon dominating phase which usually exist during solid fuel combustion. Carbon 232-238 BRF1 RNA polymerase III transcription initiation factor subunit Homo sapiens 9-12 30316115-5 2019 The flexible film of acid-functionalized carbon nanotubes termed as the CNTF placed between the composite cathode and the separator material serves as an active interlayer to boost the performance efficiency of the assembled Li-S cells. Carbon 41-47 ciliary neurotrophic factor Homo sapiens 72-76 30316115-11 2019 The use of the coconut shell derived, steam activated and acid washed carbon for making the composite cathode with sulfur and the CNTF interlayer, obtained by the acid functionalization of carbon nanotubes is a novel approach to realize Li-S cells with high capacity and excellent cycling stability, which has not yet been pursued in detail. Carbon 70-76 ciliary neurotrophic factor Homo sapiens 130-134 30316115-11 2019 The use of the coconut shell derived, steam activated and acid washed carbon for making the composite cathode with sulfur and the CNTF interlayer, obtained by the acid functionalization of carbon nanotubes is a novel approach to realize Li-S cells with high capacity and excellent cycling stability, which has not yet been pursued in detail. Carbon 189-195 ciliary neurotrophic factor Homo sapiens 130-134 29656564-8 2019 Spatially, under the influence of high nutrient concentration induced by the different circulations and coastal upwelling, slightly high carbon biomass of picophytoplankton was observed around the coastal zones of Sri Lanka island and Sumatra, as well as the southern Bay of Bengal. Carbon 137-143 sorcin Homo sapiens 214-217 30654557-3 2019 The new molecules, named amphidinolide PX1-PX3 and stragulin A (1-4), show an unprecedented carbon skeleton whose complete stereochemistry has been determined by spectroscopic and computational methods. Carbon 92-98 pannexin 1 Homo sapiens 39-42 30654557-3 2019 The new molecules, named amphidinolide PX1-PX3 and stragulin A (1-4), show an unprecedented carbon skeleton whose complete stereochemistry has been determined by spectroscopic and computational methods. Carbon 92-98 pannexin 3 Homo sapiens 43-46 30613765-0 2019 IDH3alpha regulates one-carbon metabolism in glioblastoma. Carbon 24-30 isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha Homo sapiens 0-9 30960040-3 2019 The polydimethylsiloxane (PDMS) composites containing short carbon fiber (SCF) exhibited an electrical percolation threshold at 0.45 wt % and reached a saturated electrical conductivity of 49 S/m at 8 wt % of SCF. Carbon 60-66 KIT ligand Homo sapiens 74-77 30960040-3 2019 The polydimethylsiloxane (PDMS) composites containing short carbon fiber (SCF) exhibited an electrical percolation threshold at 0.45 wt % and reached a saturated electrical conductivity of 49 S/m at 8 wt % of SCF. Carbon 60-66 KIT ligand Homo sapiens 209-212 30960040-5 2019 Furthermore, the addition of a second nanofiller of 1 wt %, such as carbon nanotube or conducting carbon black, further increased the electrical conductivity of the PDMS/SCF (8 wt %) composites to 909 S/m and 657 S/m, respectively. Carbon 68-74 KIT ligand Homo sapiens 170-173 30414894-1 2019 GPR84 was identified as a receptor for medium-chain fatty acids with carbon chain lengths of 9-14. Carbon 69-75 G protein-coupled receptor 84 Danio rerio 0-5 31580197-5 2019 Importantly, we also found that the relative ratio of carbon to nitrogen (C/N) was greatly enhanced by BIG deficiency. Carbon 54-60 auxin transport protein (BIG) Arabidopsis thaliana 103-106 31597828-5 2019 Moreover, we shed light on several mysteries, such as the C-terminal region in human TPO molecules not being found in birds, amphibians, and fish TPO molecules and the functional universalities of mutant CALR-MPL binding and EPO-EphB4 binding, in conjunction with comparative hematology. Carbon 58-59 thyroid peroxidase Homo sapiens 85-88 30385507-2 2018 MPV17 loss-of-function has been reported to result in tissue-specific nucleotide pool imbalances, which can occur in states of perturbed folate-mediated one-carbon metabolism (FOCM), but MPV17 has not been directly linked to FOCM. Carbon 157-163 mitochondrial inner membrane protein MPV17 Homo sapiens 0-5 32254937-1 2018 By coupling tyrosinase (Tyr) and beta-galactosidase (Gal) into one redox-cycling scheme, an enzyme cascade-based electrochemical immunosensor with boosted selectivity and sensitivity was constructed using polydopamine-functionalized multiwalled carbon nanotube (MWCNTs-PDA) nanohybrid modified electrodes. Carbon 245-251 tyrosinase Homo sapiens 12-22 32254937-1 2018 By coupling tyrosinase (Tyr) and beta-galactosidase (Gal) into one redox-cycling scheme, an enzyme cascade-based electrochemical immunosensor with boosted selectivity and sensitivity was constructed using polydopamine-functionalized multiwalled carbon nanotube (MWCNTs-PDA) nanohybrid modified electrodes. Carbon 245-251 tyrosinase Homo sapiens 24-27 30446437-0 2018 Structural development of non-secosteroidal vitamin D receptor (VDR) ligands without any asymmetric carbon. Carbon 100-106 vitamin D receptor Homo sapiens 44-62 30515617-4 2018 The coating also facilitates the direct electron transfer between the active site of GOx and the glassy carbon electrode (GCE). Carbon 104-110 hydroxyacid oxidase 1 Homo sapiens 85-88 30403023-6 2018 The outcome of this unique approach is reflected in the reversible capacities of 808 and 510 mA h gSe -1 achieved for the Li-oxide@separator/Se-alkali activated carbon cell before and after 100 cycles, respectively, thus demonstrating that carbon and oxide can efficiently restrict the capacity fading and improve the performances of Li-Se cells. Carbon 161-167 Gse1 coiled-coil protein Homo sapiens 98-104 30403023-6 2018 The outcome of this unique approach is reflected in the reversible capacities of 808 and 510 mA h gSe -1 achieved for the Li-oxide@separator/Se-alkali activated carbon cell before and after 100 cycles, respectively, thus demonstrating that carbon and oxide can efficiently restrict the capacity fading and improve the performances of Li-Se cells. Carbon 240-246 Gse1 coiled-coil protein Homo sapiens 98-104 30351107-7 2018 It is observed that formation of a thiazolidine ring from NAC occurs primarily in four steps, which involve proton abstraction from the thiol (SH) group of NAC and subsequent formation of an S-C bond by a nucleophilic attack of the C-S group on the protonated C-O-H group in NAC. Carbon 158-159 X-linked Kx blood group Homo sapiens 58-61 30360047-1 2018 Three-dimensional graphene oxide-carbon nanotube (GO-CNT, abbreviated as GCNT) aerogels can find wide applications in various fields. Carbon 33-39 glucosaminyl (N-acetyl) transferase family member 7 Homo sapiens 73-77 30524641-2 2018 In this article, we successfully synthesize flexible freestanding carbon nanofiber-embedded TiO2 nanoparticles (CNF-TiO2) and then apply it directly as anode in SIBs without binder or current collector. Carbon 66-72 NPHS1 adhesion molecule, nephrin Homo sapiens 112-115 30177378-3 2018 In this study, we designed and synthesized cyclopropane-based GABA analogues, which were conformationally restricted in the trans-syn-form by cyclopropylic strain based on the stereochemistry of the carbon adjacent to cyclopropane. Carbon 199-205 synemin Homo sapiens 31-34 30220061-1 2018 In this study, cobalt ferrite/mesoporous graphitic carbon nitride (CoFe2O4/mpg-C3N4) nanocomposites were successfully synthesized by using a two-step protocol. Carbon 41-50 N-methylpurine DNA glycosylase Homo sapiens 75-78 30443546-11 2018 Furthermore, we showed that the concurrent dynamic control of ERG20 and ERG9 expression, using ergosterol and carbon source regulation mechanisms, could substantially improve diterpene titer. Carbon 110-116 bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase Saccharomyces cerevisiae S288C 62-67 30342836-1 2018 In this study, commercial activated carbons (GAB and CBP) were successfully used for the removal of two phenoxy acetic class-herbicides, 4-chloro-2-methyl phenoxy acetic acid and 2.4-dichlorophenoxy acetic acid (MCPA and 2.4-D) from aqueous solution. Carbon 36-43 alpha-1-B glycoprotein Homo sapiens 45-48 30342836-3 2018 The results suggest that the microporous properties of GAB activated carbon enhanced the adsorption capacity, in comparison to CBP carbon. Carbon 69-75 alpha-1-B glycoprotein Homo sapiens 55-58 30282455-3 2018 If methylmalonyl-CoA mutase is unavailable to accept the coenzyme B12 product of adenosyltransferase, the latter catalyzes homolytic scission of the cobalt-carbon bond in an unconventional reversal of the nucleophilic displacement reaction that was used to make it. Carbon 156-162 methylmalonyl-CoA mutase Homo sapiens 3-27 29886188-0 2018 CIP2A immunosensor comprised of vertically-aligned carbon nanotube interdigitated electrodes towards point-of-care oral cancer screening. Carbon 51-57 cellular inhibitor of PP2A Homo sapiens 0-5 30323587-2 2018 Herein, we report a multifunctional nanoplatform based on hyaluronic acid (HA)-modified and graphene quantum dot (GQD)-gated hollow mesoporous carbon nanoparticle (HMCN) for anticancer drug encapsulation and targeted chemo-photothermal therapy of CD44 receptor-overexpressed cancer cells. Carbon 143-149 CD44 molecule (Indian blood group) Homo sapiens 247-251 30047210-2 2018 Herein, activated cobalt-nitrogen-doped carbon nanotube/carbon nanofiber composites (Co-N-CNT/CNF) as the effective cathodes for Li-O2 batteries are prepared by in situ chemical vapor deposition (CVD). Carbon 40-46 NPHS1 adhesion molecule, nephrin Homo sapiens 94-97 30047210-2 2018 Herein, activated cobalt-nitrogen-doped carbon nanotube/carbon nanofiber composites (Co-N-CNT/CNF) as the effective cathodes for Li-O2 batteries are prepared by in situ chemical vapor deposition (CVD). Carbon 56-62 NPHS1 adhesion molecule, nephrin Homo sapiens 94-97 30047210-4 2018 Meanwhile, the nitrogen-doped carbon nanotube/carbon nanofiber (N-CNT/CNF) and Co/CoNx serve as reaction sites to promote the formation/decomposition of discharge product. Carbon 30-36 NPHS1 adhesion molecule, nephrin Homo sapiens 70-73 30047210-4 2018 Meanwhile, the nitrogen-doped carbon nanotube/carbon nanofiber (N-CNT/CNF) and Co/CoNx serve as reaction sites to promote the formation/decomposition of discharge product. Carbon 46-52 NPHS1 adhesion molecule, nephrin Homo sapiens 70-73 30275950-7 2018 Also, unlike other folate one-carbon enzymes, the MTHFD2 protein has a short half-life and responds rapidly to serum. Carbon 30-36 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 50-56 30118203-1 2018 In the nearly 80 years since catalytic hydroformylation was first reported, hundreds of billions of pounds of aldehyde have been produced by this atom efficient one-carbon homologation of alkenes in the presence of H2 and CO. Carbon 165-171 relaxin 2 Homo sapiens 215-224 30137083-1 2018 Surface-confined host-guest chemistry at the air/solid interface is used for trapping a functionalized 3D Zn-phthalocyanine complex into a 2D porous supramolecular template allowing the large area functionalization of an sp2-hybridized carbon-based substrate as evidenced by STM, resonance Raman spectroscopy, and water contact angle measurements. Carbon 236-242 sulfotransferase family 1A member 3 Homo sapiens 275-278 29932987-8 2018 Employing a poly I:C-inducible Mx1-Cre-based rac1 knock-out, which allows a more widespread rac1 deletion in both hepatocytes and non-hepatocytes, we observed substantial differences regarding both basal and LPS-stimulated cytokine expression profiles as compared to the Alb-Cre system. Carbon 19-20 MX dynamin-like GTPase 1 Mus musculus 31-34 30103543-9 2018 In this study, we present a label-free chemiresistive immunosensor for the detection of the DENV NS1 protein utilizing a network of single-walled carbon nanotubes functionalized with anti-dengue NS1 monoclonal antibodies. Carbon 146-152 influenza virus NS1A binding protein Homo sapiens 97-100 30084797-4 2018 By adding the PEG2000-SH and the C13 carbon chain to a NIR representative dye IR780, the new formed material PEG-IR780-C13 shows good solubility in water. Carbon 37-43 homeobox C13 Homo sapiens 33-36 30084797-4 2018 By adding the PEG2000-SH and the C13 carbon chain to a NIR representative dye IR780, the new formed material PEG-IR780-C13 shows good solubility in water. Carbon 37-43 homeobox C13 Homo sapiens 119-122 29697864-3 2018 Herein, a convenient route for the synthesis of Mn3 O4 nanoparticles grown in situ on hollow carbon nanofiber (denoted as HCF/Mn3 O4 ) is reported. Carbon 93-99 host cell factor C1 Homo sapiens 122-132 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 ATP citrate lyase Homo sapiens 167-171 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 glucokinase Homo sapiens 180-183 29970880-2 2018 Importantly, several genes involved in the "Central carbon metabolism pathway in cancer", as reported in the Kyoto Encyclopedia of Genes and Genomes, were either up- (ACLY, ERBB2, GCK, MYC, PGM, PKFB2, SLC1A5, SLC7A5, SLC16A3,) or down- (IDH, MDH1, OGDH, P53, PDK) regulated in response to the drug association. Carbon 52-58 solute carrier family 1 member 5 Homo sapiens 202-208 29883121-0 2018 Hierarchically Porous N,S-Codoped Carbon-Embedded Dual Phase MnO/MnS Nanoparticles for Efficient Lithium Ion Storage. Carbon 34-40 glycophorin E (MNS blood group) Homo sapiens 65-68 29883121-1 2018 An intriguingly nanostructured composite comprising of MnO/MnS nanoparticles embedded in an N,S-codoped carbon frame (MnO/MnS@C) is designed here and employed as a promising Li-ion storage electrode material to address the challenge of inferior conductivity and large volume change toward manganese chalcogenide-based anode. Carbon 104-110 glycophorin E (MNS blood group) Homo sapiens 59-62 29883121-1 2018 An intriguingly nanostructured composite comprising of MnO/MnS nanoparticles embedded in an N,S-codoped carbon frame (MnO/MnS@C) is designed here and employed as a promising Li-ion storage electrode material to address the challenge of inferior conductivity and large volume change toward manganese chalcogenide-based anode. Carbon 104-110 glycophorin E (MNS blood group) Homo sapiens 122-125 29799717-0 2018 Three-Dimensional Graphene-Carbon Nanotube-Ni Hierarchical Architecture as a Polysulfide Trap for Lithium-Sulfur Batteries. Carbon 27-33 TRAP Homo sapiens 89-93 29847722-1 2018 This paper describes a simple approach to the large-scale synthesis of colloidal Si nanocrystals and their processing into spin-on carbon-free nanocrystalline Si films. Carbon 131-137 spindlin 1 Homo sapiens 123-127 29601190-0 2018 Access to Wieland-Miescher Diketone-Derived Building Blocks by Stereoselective Construction of the C-9 Quaternary Carbon Center Using the Mukaiyama Aldol Reaction. Carbon 114-120 complement C9 Homo sapiens 99-102 29665361-0 2018 RNA-Seq analysis of global transcriptomic changes suggests a roles for the MAPK pathway and carbon metabolism in cell wall maintenance in a Saccharomyces cerevisiae FKS1 mutant. Carbon 92-98 1,3-beta-D-glucan synthase Saccharomyces cerevisiae S288C 165-169 29768237-4 2018 Furthermore, the CNF/MWCNT carbon aerogels (CMCA) can be recycled many times by distillation and combustion, satisfying the requirements of practical oil-water separation. Carbon 27-33 NPHS1 adhesion molecule, nephrin Homo sapiens 17-20 29233911-4 2018 Here, we performed for the first time an in-depth site-specific N- and O-glycosylation analysis of C1-Inh combining various mass spectrometric approaches, including C18-porous graphitized carbon (PGC)-LC-ESI-QTOF-MS/MS applying stepping-energy collision-induced dissociation (CID) and electron-transfer dissociation (ETD). Carbon 188-194 serpin family G member 1 Homo sapiens 99-105 29686055-4 2018 Mutation of RAPTOR1B resulted in a strong reduction of TOR kinase activity, leading to massive changes in central carbon and nitrogen metabolism, accumulation of excess starch, and induction of autophagy. Carbon 114-120 Regulatory-associated protein of TOR 1 Arabidopsis thaliana 12-20 30079190-0 2018 Modulating the oxygen reduction activity of heteroatom-doped carbon catalysts via the triple effect: charge, spin density and ligand effect. Carbon 61-67 spindlin 1 Homo sapiens 109-113 30079190-3 2018 The results of the DFT calculations indicate that the intrinsic catalytic activity and the ORR mechanism depend on the triple effect, that is, the charge, the spin density and the coordinate state (ligand effect) of the carbon sites. Carbon 220-226 spindlin 1 Homo sapiens 159-163 29664601-8 2018 Organozinc reagents can be employed as nucleophiles, and the CF2 fragment can insert into the carbon-zinc bond. Carbon 94-100 ATPase H+ transporting accessory protein 1 Homo sapiens 61-64 29782002-4 2018 In this report, we show a method of estimating the number of carbon and double bonds in a LCB and an N-acyl moiety based on their corresponding product ions in MS/MS/MS (MS3) experiments. Carbon 61-67 clathrin light chain B Homo sapiens 90-93 30016261-4 2018 For the first time, the bimetallic cobalt-iron diselenide nanosphere entrapped functionalized carbon nanofiber (CoFeSe2/f-CNF) composite have been synthesized by using simple hydrothermal synthesis and used as an electrode material for efficient electrochemical detection of caffeic acid (CA). Carbon 94-100 NPHS1 adhesion molecule, nephrin Homo sapiens 122-125 30016261-6 2018 In addition, the electrochemical properties of CoFeSe2/f-CNF modified glassy carbon electrode (GCE) towards CA sensing were investigated by using cyclic voltammetry, differential pulse voltammetry and electrochemical impedance spectroscopy. Carbon 77-83 NPHS1 adhesion molecule, nephrin Homo sapiens 57-60 29694444-0 2018 One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status. Carbon 4-10 KRAS proto-oncogene, GTPase Homo sapiens 95-99 29615678-2 2018 Glucose carbon can be diverted from mitochondria by the pentose phosphate pathway (via glucose 6-phosphate dehydrogenase, G6PDH), lactate production (via lactate dehydrogenase, LDH), and rejection of carbon from the TCA cycle (via pyruvate dehydrogenase kinase, PDK), all of which can be upregulated in cancer cells. Carbon 8-14 glucose-6-phosphate dehydrogenase Homo sapiens 87-120 29226424-5 2018 Poly(I:C) induced the production of prostaglandin E2 in OHSCs by increasing cyclooxygenase (COX-2) and microsomal prostaglandin E synthase (mPGES)-1. Carbon 7-8 prostaglandin E synthase Homo sapiens 103-148 29615218-14 2018 Black carbon exposure was associated with elevated promoter methylation in APEX1 (9 16%, 4 06 to 14 25, p=0 01) and ERCC4 (27 56%, 17 58 to 37 55, p<0 0001). Carbon 6-12 ERCC excision repair 4, endonuclease catalytic subunit Homo sapiens 116-121 29537039-3 2018 The obtained results complement not only existing ones, but for the first time the photoelectron spectra of C3, cyclic and linear C3H (c,l-C3H) as well as of the excited states of C3H3 are reported. Carbon 21-22 complement C3 Homo sapiens 108-133 29350621-1 2018 Binder-free nickel cobaltite on a carbon nanofiber (NiCo2O4@CNF) anode for lithium ion batteries was prepared via a two-step procedure of electrospinning and electrodeposition. Carbon 34-40 NPHS1 adhesion molecule, nephrin Homo sapiens 60-63 29350629-1 2018 In the present work, a conductive film of silver nanoparticles (nAg) as a novel heating element type, called susceptor, was developed and tested for induction welding of carbon fiber/polyphenylene sulfide (CF/PPS) thermoplastic composites, i.e., unidirectional pre-impregnated 16 plies of CF/PPS compression-molded in a quasi-isotropic stacking sequence. Carbon 170-176 NBAS subunit of NRZ tethering complex Homo sapiens 64-67 29040915-4 2018 The PANI1600@CNTs composite modified glassy carbon electrodes based on glucose oxidase (GOx) and laccase (Lac) exhibit high electrochemical performance. Carbon 44-50 hydroxyacid oxidase 1 Homo sapiens 71-86 29040915-4 2018 The PANI1600@CNTs composite modified glassy carbon electrodes based on glucose oxidase (GOx) and laccase (Lac) exhibit high electrochemical performance. Carbon 44-50 hydroxyacid oxidase 1 Homo sapiens 88-91 29289733-8 2018 Finally, the preliminary tests reveal that the electrode materials based on MoS/rGO and a low-cost carbon cloth (CC) composite MoS/rGO/CC may have a potential for an application in energy storage as performant and flexible supercapacitor, showing specific capacitance as high as 870 F g-1 at 10 mV s-1 and excellent stability after 5000 cycles. Carbon 99-105 MOS proto-oncogene, serine/threonine kinase Homo sapiens 127-130 29414038-1 2018 15-hydroxyprostaglandin dehydrogenase (15-PGDH) is a prostaglandin metabolizing enzyme that oxidizes the hydroxyl group at carbon 15 (C15). Carbon 123-129 carbonyl reductase 1 Homo sapiens 0-37 29414038-1 2018 15-hydroxyprostaglandin dehydrogenase (15-PGDH) is a prostaglandin metabolizing enzyme that oxidizes the hydroxyl group at carbon 15 (C15). Carbon 123-129 carbonyl reductase 1 Homo sapiens 39-46 29452640-3 2018 SHMT2 catalyzes the first step in mitochondrial one-carbon metabolism, which, particularly in proliferating cells, produces tetrahydrofolate (THF)-conjugated one-carbon units used in cytoplasmic reactions despite the presence of a parallel cytoplasmic pathway. Carbon 52-58 serine hydroxymethyltransferase 2 Homo sapiens 0-5 29452640-3 2018 SHMT2 catalyzes the first step in mitochondrial one-carbon metabolism, which, particularly in proliferating cells, produces tetrahydrofolate (THF)-conjugated one-carbon units used in cytoplasmic reactions despite the presence of a parallel cytoplasmic pathway. Carbon 162-168 serine hydroxymethyltransferase 2 Homo sapiens 0-5 29527428-3 2018 The resulting CNF/PVA/GO aerogels were synthesized through an environmentally friendly freeze-drying process and then carbonized to yield CNF/PVA/GO carbon aerogels with low density (18.41 mg cm-3), high porosity (98.98%), a water contact angle of 156 (super-hydrophobic) and high oil absorption capacity (97 times its own weight). Carbon 118-124 NPHS1 adhesion molecule, nephrin Homo sapiens 14-17 29350730-5 2018 The 3D porous ZGM-SiC-1 and AGM-SiC-3 display strong affinity to S8 and LiPS with the direct Si-S and Li-C interactions, which are comparable to the case of the N doped carbon host. Carbon 169-175 Fli-1 proto-oncogene, ETS transcription factor Homo sapiens 18-23 29416063-2 2018 Here, we show that Pemt and Gnmt, key one-carbon cycle genes regulating PC/SAM levels, are downregulated after feeding, leading to decreased PC and increased SAM levels, but these effects are blunted in small heterodimer partner (SHP)-null or FGF15-null mice. Carbon 42-48 glycine N-methyltransferase Mus musculus 28-32 29416063-2 2018 Here, we show that Pemt and Gnmt, key one-carbon cycle genes regulating PC/SAM levels, are downregulated after feeding, leading to decreased PC and increased SAM levels, but these effects are blunted in small heterodimer partner (SHP)-null or FGF15-null mice. Carbon 42-48 nuclear receptor subfamily 0, group B, member 2 Mus musculus 230-233 29228194-2 2018 Consequently, our efforts to tap other carbon sources are steadily increasing. Carbon 39-45 nuclear RNA export factor 1 Homo sapiens 29-32 29197127-3 2018 However, the metabolic utilisation of preferred carbon and nitrogen sources, encountered in a host niche-dependent manner, is known as carbon catabolite and nitrogen catabolite repression (CCR, NCR), and has been shown to be important for virulence. Carbon 48-54 Neutrophil migration (granulocyte glycoprotein) Homo sapiens 194-197 29323365-3 2018 In contrast, reaction of 1a with [Ir2Cl2(COD)2] (COD = 1,5-cyclo-octadiene) affords the complex [IrCl(COD){kappa2-P,P"-H2C(NCH2PPh2)2C10H6}], thermolysis of which affords cyclo-octene and the pincer-NHC complex [IrCl{kappa3-C,P,P"-C(NCH2PPh2)2C10H6}]. Carbon 223-225 COD2 Homo sapiens 41-46 29283259-2 2018 The synthesis features a photoredox organocatalytic asymmetric alkylation to generate the original C15 chirality, a photocatalytic C-H functionalization of 3-methylindole in flow for constructing the C16 all-carbon quaternary center, a regioselective 1,3-dipolar cycloaddition, and an intramolecular Henry reaction to assemble the pentacyclic core of the target molecule. Carbon 208-214 placenta associated 8 Homo sapiens 99-102 29346402-10 2018 These clusters contained putative binding sites for the carbon source responsive transcription factors Mig1 and Adr1. Carbon 56-62 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 112-116 29375510-6 2017 This suggests a trend to streamline the regulation of C/N metabolism in late-branching Prochlorococcus strains (MED4 and SS120), in adaptation to the rather stable conditions found in the oligotrophic ocean gyres where this microorganism is most abundant. Carbon 54-55 mediator complex subunit 4 Homo sapiens 112-116 29112790-1 2018 More diverse crop rotations have been promoted for their potential to remediate the range of ecosystem services compromised by biologically simplified grain-based agroecosystems, including increasing soil organic carbon (SOC). Carbon 213-219 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 13-17 29098803-3 2017 Over CoCl2 6 H2 O, a high carbon yield of C13 oxygenates (about 75 %) can be achieved under mild conditions (353 K, 20 h). Carbon 27-33 homeobox C13 Homo sapiens 43-46 29422980-2 2017 In this paper, Indium Sulfide/Flexible Electrospun Carbon Nanofiber (In2S3/CNF) heterogeneous systems were synthesized by a facile one-pot hydrothermal method. Carbon 51-57 NPHS1 adhesion molecule, nephrin Homo sapiens 75-78 28972046-6 2017 Therapeutic inhibition of PI3Kbeta also upregulated PDHK4 and increased PDH phosphorylation, indicative of reduced carbon flux into the TCA cycle. Carbon 115-121 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Homo sapiens 26-34 28972046-7 2017 Consistent with this, metabolomic analysis revealed a number of changes in key carbon pathways, nucleotide, and amino acid biosynthesis.Conclusions: This study identifies novel mechanistic biomarkers of PI3Kbeta inhibition in PTEN-null tumors supporting the concept that targeting PI3Kbeta may exploit a metabolic dependency that contributes to therapeutic benefit in inducing cell stress. Carbon 79-85 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Homo sapiens 203-211 29242833-3 2017 However, a C. albicans put3 null mutant cannot grow on proline, suggesting that as in S. cerevisiae, C. albicans Put3 (CaPut3) is required for proline catabolism, and because the C. albicans put3 null mutant grew efficiently on glutamate as the sole carbon or nitrogen source, it appears that CaPut3 also regulates the early genes of the pathway. Carbon 250-256 Put3p Saccharomyces cerevisiae S288C 113-117 29242833-10 2017 We show that the Put3 transcription factor allows the pathogen to completely degrade proline to usable nitrogen and carbon by evading regulatory restrictions imposed on its S. cerevisiae ortholog, which mandates conditional use of proline only as a nitrogen source in the baker"s yeast. Carbon 116-122 Put3p Saccharomyces cerevisiae S288C 17-21 29399410-4 2018 In our experiments, poly(I:C) stimulated expression of both PD-L1 and PD-L2 on glioblastoma cells, and a pro-inflammatory secretome, including type I interferons (IFN) and chemokines CXCL9, CXCL10, CCL4 and CCL5. Carbon 27-28 programmed cell death 1 ligand 2 Homo sapiens 70-75 29399410-4 2018 In our experiments, poly(I:C) stimulated expression of both PD-L1 and PD-L2 on glioblastoma cells, and a pro-inflammatory secretome, including type I interferons (IFN) and chemokines CXCL9, CXCL10, CCL4 and CCL5. Carbon 27-28 C-X-C motif chemokine ligand 10 Homo sapiens 190-196 29399410-4 2018 In our experiments, poly(I:C) stimulated expression of both PD-L1 and PD-L2 on glioblastoma cells, and a pro-inflammatory secretome, including type I interferons (IFN) and chemokines CXCL9, CXCL10, CCL4 and CCL5. Carbon 27-28 C-C motif chemokine ligand 5 Homo sapiens 207-211 28772201-0 2017 Effective immobilization of alcohol dehydrogenase on carbon nanoscaffolds for ethanol biofuel cell. Carbon 53-59 aldo-keto reductase family 1 member A1 Homo sapiens 28-49 28772201-1 2017 An efficient approach for immobilizing alcohol dehydrogenase (ADH) while enhancing its electron transfer ability has been developed using poly(2-(trimethylamino)ethyl methacrylate) (MADQUAT) cationic polymer and carbon nanoscaffolds. Carbon 212-218 aldo-keto reductase family 1 member A1 Homo sapiens 39-60 28772201-1 2017 An efficient approach for immobilizing alcohol dehydrogenase (ADH) while enhancing its electron transfer ability has been developed using poly(2-(trimethylamino)ethyl methacrylate) (MADQUAT) cationic polymer and carbon nanoscaffolds. Carbon 212-218 aldo-keto reductase family 1 member A1 Homo sapiens 62-65 28772201-3 2017 The ADH entrapped within the MADQUAT that was present on the carbon nanoscaffolds exhibited a high electron exchange capability with the electrode through its cofactor beta-nicotinamide adenine dinucleotide hydrate and beta-nicotinamide adenine dinucleotide reduced disodium salt hydrate (NAD+/NADH) redox reaction. Carbon 61-67 aldo-keto reductase family 1 member A1 Homo sapiens 4-7 28972198-7 2017 We concluded that the ET2 and EH3 defects: (i) act as majority carrier removal traps, (ii) exhibit a low thermal stability and (iii) can be related to the simple point-like defects introduced by light ion implantation, namely interstitials and/or complex of interstitials and vacancies in both carbon and silicon sub-lattices. Carbon 294-300 endothelin 2 Homo sapiens 22-25 29064660-0 2017 Graphene-Carbon-Metal Composite Film for a Flexible Heat Sink. Carbon 9-15 tribbles pseudokinase 3 Homo sapiens 57-61 29064660-2 2017 Herein, we report a comprehensive method to dissipate the generated heat to a vast area by using the new type of graphene-carbon-metal composite film as a heat sink. Carbon 122-128 tribbles pseudokinase 3 Homo sapiens 160-164 29064660-6 2017 This result reveals that the graphene-carbon-metal composite film is one of the most promising materials for a heat sink of electronic devices in modern electronics. Carbon 38-44 tribbles pseudokinase 3 Homo sapiens 116-120 29083165-5 2017 The evolution of the core-to-valence resonances at the carbon K-edge establishes an ultrafast population of the T1 state (3pipi*) in AcAc via intersystem crossing on a 1.5 +- 0.2 ps time scale. Carbon 55-61 acetyl-CoA carboxylase alpha Homo sapiens 133-137 28750239-2 2017 In this paper, an "off-on" method for highly sensitive and selective detection of Hg2+ and l-cysteine (l-Cys) or Hg2+ and I- using home-made nitrogen-doped carbon quantum dots (N-CQDs) as fluorescent probe was reported. Carbon 156-162 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 82-85 28750239-2 2017 In this paper, an "off-on" method for highly sensitive and selective detection of Hg2+ and l-cysteine (l-Cys) or Hg2+ and I- using home-made nitrogen-doped carbon quantum dots (N-CQDs) as fluorescent probe was reported. Carbon 156-162 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 113-116 29039674-8 2017 Time evolution analysis of the charge and spin line densities evidences that the charge and spin density waves are elementary excitations of metallic carbon nanotubes. Carbon 150-156 spindlin 1 Homo sapiens 92-96 29109421-9 2017 Additionally, we discovered that using glucose as the sole carbon source to pre-culture the strain before induction could greatly enhance apidaecin production. Carbon 59-65 LOC406115 Apis mellifera 138-147 28958808-10 2017 Finally, we showed that, as adjuvants, CpG-B, R848 and Poly I:C can all enhance antigen specific CD4+ T cell response, while only R848 and Poly I:C induced CD8+ cytotoxic T cells response to a CD40-targeting HIV vaccine in humanized mice, correlated with their ability to activate human mDCs but not pDCs. Carbon 39-40 CD4 antigen Mus musculus 97-100 28968774-5 2017 Among these, associations with the levels of CRP (beta= -0.53; P = 0.01) and CCL15/MIP-1D (beta = 0.20; P = 0.02) were observed in workers exposed to DEE and with increasing elemental carbon exposure levels (Ptrends <0.05) in multivariable linear regression models. Carbon 184-190 C-C motif chemokine ligand 15 Homo sapiens 77-82 28968774-5 2017 Among these, associations with the levels of CRP (beta= -0.53; P = 0.01) and CCL15/MIP-1D (beta = 0.20; P = 0.02) were observed in workers exposed to DEE and with increasing elemental carbon exposure levels (Ptrends <0.05) in multivariable linear regression models. Carbon 184-190 C-C motif chemokine ligand 15 Homo sapiens 83-89 28956577-5 2017 By increasing the length of dithiol alkyl spacers containing two to eleven carbons along the spacer backbone (C2 to C11), we can modulate the mesophase from nematic to smectic, tailor the nematic to isotropic transition temperature between 90 and 140 C, and increase the average work capacity from 128 to 262 kJ m-3. Carbon 75-82 RNA polymerase III subunit K Homo sapiens 116-119 29042654-2 2017 The bioanode was developed by the deposition of the PIn-Au-SGO nanocomposite with subsequent immobilization of ferritin (Frt) and glucose oxidase (GOx) on the glassy carbon electrode (GC). Carbon 166-172 hydroxyacid oxidase 1 Homo sapiens 130-145 29042654-2 2017 The bioanode was developed by the deposition of the PIn-Au-SGO nanocomposite with subsequent immobilization of ferritin (Frt) and glucose oxidase (GOx) on the glassy carbon electrode (GC). Carbon 166-172 hydroxyacid oxidase 1 Homo sapiens 147-150 28718966-2 2017 Density functional theory calculations toward this reaction reveal that terminal alkynes with TMS-N3 participated hydroazidation proceed through HN3 formation, deprotonation and silver acetylides formation, nucleophilic addition, and protonation of terminal carbon by AgHCO3 . Carbon 258-264 MT-RNR2 like 3 (pseudogene) Homo sapiens 145-148 28830930-6 2017 We found that heme induces transcription of HAP4, the transcriptional activation subunit of the Hap2/3/4/5p complex, required for growth on nonfermentable carbon sources, in a Hap1p- and Hap2/3/4/5p-dependent manner. Carbon 155-161 transcription factor HAP4 Saccharomyces cerevisiae S288C 44-48 28784815-7 2017 The findings from the present experiments using a pspA deletion mutant have confirmed the physiological role of iPSPs as serine producers and show that serine is a major donor of one-carbon units in H. thermophilusIMPORTANCE Serine biosynthesis and catabolism pathways are intimately related to the metabolism of 5,10-CH2-THF, a one-carbon donor that is utilized for the biosynthesis of various essential compounds. Carbon 183-189 surfactant protein A2 Homo sapiens 50-54 28784815-7 2017 The findings from the present experiments using a pspA deletion mutant have confirmed the physiological role of iPSPs as serine producers and show that serine is a major donor of one-carbon units in H. thermophilusIMPORTANCE Serine biosynthesis and catabolism pathways are intimately related to the metabolism of 5,10-CH2-THF, a one-carbon donor that is utilized for the biosynthesis of various essential compounds. Carbon 333-339 surfactant protein A2 Homo sapiens 50-54 28910083-3 2017 To that end, cobalt-based carbon nanotubes (Co-CNTs) were developed for the simultaneous Hg2+ removal and sulfite oxidation in this work. Carbon 26-32 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 89-92 28640985-4 2017 Here, we report that the interaction between PSAP and PGRN requires the linker region of saposin B and C (BC linker). Carbon 103-104 prosaposin Homo sapiens 45-49 28957510-6 2017 While many of the adaptive mutations occur in genes that encode proteins with known roles in glucose sensing and transport, we discover mutations in genes with no canonical role in carbon utilization (IPT1 and MOT3), as well as identify novel dominant mutations in glucose signal transducers thought to only accumulate recessive mutations in carbon limited environments (MTH1 and RGT1). Carbon 342-348 Mot3p Saccharomyces cerevisiae S288C 210-214 28914300-1 2017 A Mn-incorporated Ni(OH)2/carbon fiber cloth (Mn-Ni(OH)2/CFC) fabricated via a room-temperature solution route exhibited superior electrocatalytic activities of the oxygen reduction and urea oxidation reactions, delivering 12-21% energy saving in the charging process of Mn-Ni(OH)2/CFC assembled Zn-air batteries in the presence of 0.5 M urea compared to the battery without urea. Carbon 26-32 tubulin folding cofactor C Homo sapiens 57-60 28914300-1 2017 A Mn-incorporated Ni(OH)2/carbon fiber cloth (Mn-Ni(OH)2/CFC) fabricated via a room-temperature solution route exhibited superior electrocatalytic activities of the oxygen reduction and urea oxidation reactions, delivering 12-21% energy saving in the charging process of Mn-Ni(OH)2/CFC assembled Zn-air batteries in the presence of 0.5 M urea compared to the battery without urea. Carbon 26-32 tubulin folding cofactor C Homo sapiens 282-285 28647381-8 2017 Montelukast significantly attenuated the poly I:C-induced increase in the number of eosinophils and levels of IL-13, IL-9, and CCL3 in BALF and airway hyperresponsiveness in both the reliever and controller models. Carbon 48-49 interleukin 9 Mus musculus 117-121 28751572-7 2017 Positive associations were also observed for nitrogen oxides with interleukin-6 and for black carbon, sulfate, and ozone with tumor necrosis factor receptor 2. Carbon 94-100 TNF receptor superfamily member 1B Homo sapiens 126-158 28746823-5 2017 Irx1-/- mice show delayed lung maturation characterized by defective surfactant protein secretion and Irx1 marks a population of SP-C expressing alveolar type II cells. Carbon 132-133 Iroquois homeobox 1 Mus musculus 102-106 28594637-1 2017 The application of an in situ potential difference between carbon fibres and a graphite foil counter electrode (300 V, generating an electric field ca 0.3-0.7 V mum-1), during the chemical vapour deposition synthesis of carbon nanotube (CNT) grafted carbon fibres, significantly improves the uniformity of growth without reducing the tensile properties of the underlying carbon fibres. Carbon 220-226 PWWP domain containing 3A, DNA repair factor Homo sapiens 161-166 28594637-1 2017 The application of an in situ potential difference between carbon fibres and a graphite foil counter electrode (300 V, generating an electric field ca 0.3-0.7 V mum-1), during the chemical vapour deposition synthesis of carbon nanotube (CNT) grafted carbon fibres, significantly improves the uniformity of growth without reducing the tensile properties of the underlying carbon fibres. Carbon 220-226 PWWP domain containing 3A, DNA repair factor Homo sapiens 161-166 28594637-1 2017 The application of an in situ potential difference between carbon fibres and a graphite foil counter electrode (300 V, generating an electric field ca 0.3-0.7 V mum-1), during the chemical vapour deposition synthesis of carbon nanotube (CNT) grafted carbon fibres, significantly improves the uniformity of growth without reducing the tensile properties of the underlying carbon fibres. Carbon 220-226 PWWP domain containing 3A, DNA repair factor Homo sapiens 161-166 28747687-1 2017 Carbon (C) surface segregation from bulk stabilizes the Fe(0 18 1) vicinal surface by forming a c(3[Formula: see text] x [Formula: see text] reconstruction with C zig-zag chains oriented at 45 with respect to the iron surface steps. Carbon 0-6 alpha-2-glycoprotein 1, zinc-binding Homo sapiens 167-170 28459242-5 2017 One unusual oxidation product is the planar NiII-N3S complex [Ni(Lox)] (5; Lox = 2-(5,5-dimethyl-2-(pyridin-2-yl)thiazolidin-3-yl)-N-(2-mercaptoethyl)acetamide), where two-electron oxidation takes place at the substituted thiolate and py-CH2 carbon to generate a thiazolidine heterocycle. Carbon 242-248 lysyl oxidase Homo sapiens 65-68 28459242-5 2017 One unusual oxidation product is the planar NiII-N3S complex [Ni(Lox)] (5; Lox = 2-(5,5-dimethyl-2-(pyridin-2-yl)thiazolidin-3-yl)-N-(2-mercaptoethyl)acetamide), where two-electron oxidation takes place at the substituted thiolate and py-CH2 carbon to generate a thiazolidine heterocycle. Carbon 242-248 lysyl oxidase Homo sapiens 75-78 28736527-4 2017 We found that expression of human COQ9 rescues the growth of the temperature-sensitive yeast mutant, coq9-ts19, on a non-fermentable carbon source and increases the content of Q6, by enhancing Q biosynthesis from 4-hydroxybenzoic acid (4HB). Carbon 133-139 coenzyme Q9 Homo sapiens 34-38 28581287-0 2017 Electrochemical Detection of Ultratrace (Picomolar) Levels of Hg2+ Using a Silver Nanoparticle-Modified Glassy Carbon Electrode. Carbon 111-117 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 62-65 28581287-1 2017 Ultratrace levels of Hg2+ have been quantified by undertaking linear sweep voltammetry with a silver nanoparticle-modified glassy carbon electrode (AgNP-GCE) in aqueous solutions containing Hg2+. Carbon 130-136 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 21-24 28488139-2 2017 The aim of this work was to maximize the production of Aspergillus ibericus lipase under SSF of olive pomace (OP) and wheat bran (WB), evaluating the effect on lipase production of C/N ratio, lipids, phenols, content of sugars of substrates and nitrogen source addition. Carbon 181-182 probable feruloyl esterase A Triticum aestivum 160-166 27957768-1 2017 Here, we studied the influence of the methoxyl groups attached at C-7 and C-2" of natural and synthetic 1-arylindanes on the chemical shift of the signal of bibenzylic hydrogen and carbon atoms and J1,2 coupling constants. Carbon 181-187 complement C7 Homo sapiens 66-69 28508512-3 2017 Here, ultralight and multifunctional reduced graphene oxide/carbon nanofiber (RGO/CNF) aerogels are fabricated from graphene oxide and low-cost, industrially produced bacterial cellulose by a three-step process of freeze-casting, freeze-drying, and pyrolysis. Carbon 60-66 NPHS1 adhesion molecule, nephrin Homo sapiens 82-85 28427649-2 2017 In this research, humic acid was used as a source of dissolved organic carbon (DOC) in drinking water (up to 3mgL-1). Carbon 71-77 LLGL scribble cell polarity complex component 1 Homo sapiens 110-115 28166201-3 2017 Here we show that mitochondrial phosphoenolpyruvate carboxykinase (PCK2), the hub molecule linking tricarboxylic acid (TCA) cycle, glycolysis and gluconeogenesis by conversion of mitochondrial oxaloacetate (OAA) to phosphoenolpyruvate, regulates glucose carbon flow direction in stem-like cells that repopulate tumors (tumor-repopulating cells (TRCs)). Carbon 254-260 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 67-71 28166201-4 2017 PCK2 downregulation accelerated biosynthesis and transportation of citrate from mitochondria to the cytosol, leading to cytosolic glucose carbon flow via OAA-malate-pyruvate and acetyl-CoA-fatty acid pathways in TRCs. Carbon 138-144 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 0-4 28166201-5 2017 On the other hand, downregulating PCK2 hindered fumarate carbon flows in TCA cycle, leading to attenuated oxidative phosphorylation. Carbon 57-63 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 34-38 28562582-7 2017 Instead, BCR loss induces the rewiring of central carbon metabolism, increasing the sensitivity of receptor-less lymphoma cells to nutrient restriction. Carbon 50-56 BCR activator of RhoGEF and GTPase Homo sapiens 9-12 28513717-0 2017 In situ generation of less accessible Boc-imines from aldehydes: construction of a quaternary carbon by the Mannich reaction or unprecedented aldol reaction. Carbon 94-100 BOC cell adhesion associated, oncogene regulated Homo sapiens 38-41 27575455-2 2017 Maf1 from yeast Saccharomyces cerevisiae mediates repression of trna transcription when cells are transferred from medium with glucose to medium with glycerol, a non-fermentable carbon source. Carbon 178-184 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 0-4 28213255-0 2017 Amperometric flow injection analysis of glucose using immobilized glucose oxidase on nano-composite carbon nanotubes-platinum nanoparticles carbon paste electrode. Carbon 100-106 hydroxyacid oxidase 1 Homo sapiens 66-81 28213255-0 2017 Amperometric flow injection analysis of glucose using immobilized glucose oxidase on nano-composite carbon nanotubes-platinum nanoparticles carbon paste electrode. Carbon 140-146 hydroxyacid oxidase 1 Homo sapiens 66-81 28213255-1 2017 We report a novel amperometric glucose biosensor based on glucose oxidase (GOx) immobilized on a carbon nanotube (CNTs)-poly(diallyldimethyl-ammonium chloride) (PDDA)-platinum nanoparticle (PtNPs) modified carbon-paste electrode (CNTs-PDDA-PtNPs/CPE). Carbon 97-103 hydroxyacid oxidase 1 Homo sapiens 58-73 28213255-1 2017 We report a novel amperometric glucose biosensor based on glucose oxidase (GOx) immobilized on a carbon nanotube (CNTs)-poly(diallyldimethyl-ammonium chloride) (PDDA)-platinum nanoparticle (PtNPs) modified carbon-paste electrode (CNTs-PDDA-PtNPs/CPE). Carbon 97-103 hydroxyacid oxidase 1 Homo sapiens 75-78 28213255-1 2017 We report a novel amperometric glucose biosensor based on glucose oxidase (GOx) immobilized on a carbon nanotube (CNTs)-poly(diallyldimethyl-ammonium chloride) (PDDA)-platinum nanoparticle (PtNPs) modified carbon-paste electrode (CNTs-PDDA-PtNPs/CPE). Carbon 206-212 hydroxyacid oxidase 1 Homo sapiens 58-73 28213255-1 2017 We report a novel amperometric glucose biosensor based on glucose oxidase (GOx) immobilized on a carbon nanotube (CNTs)-poly(diallyldimethyl-ammonium chloride) (PDDA)-platinum nanoparticle (PtNPs) modified carbon-paste electrode (CNTs-PDDA-PtNPs/CPE). Carbon 206-212 hydroxyacid oxidase 1 Homo sapiens 75-78 28351631-0 2017 Fluorescent nitrogen and sulfur co-doped carbon dots from casein and their applications for sensitive detection of Hg2+ and biothiols and cellular imaging. Carbon 41-47 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 115-118 28421067-4 2017 The results suggested a close association between C-C motif chemokine ligand 2 (CCL2) expressions and ALI induced by a lethal H7N9 virus strain (A/Hebei/01/2013). Carbon 52-53 chemokine (C-C motif) ligand 2 Mus musculus 80-84 28294252-0 2017 Spin-orbit coupling in nearly metallic chiral carbon nanotubes: a density-functional based study. Carbon 46-52 spindlin 1 Homo sapiens 0-4 28040539-1 2017 A new model is developed to predict the competitive adsorption isotherms of atrazine, methyl tertiary butyl ether (MTBE), 2-methylisoborneol (2-MIB) and 2,4,6-trichlorophenol onto activated carbons (ACs) in natural water. Carbon 190-197 MIB E3 ubiquitin protein ligase 1 Homo sapiens 144-147 28040539-1 2017 A new model is developed to predict the competitive adsorption isotherms of atrazine, methyl tertiary butyl ether (MTBE), 2-methylisoborneol (2-MIB) and 2,4,6-trichlorophenol onto activated carbons (ACs) in natural water. Carbon 199-202 MIB E3 ubiquitin protein ligase 1 Homo sapiens 144-147 27138382-1 2017 AIM: To investigate whether plain cone-beam computed tomography (CT) immediately after conventional transcatheter arterial chemoembolization (c-TACE) can help to predict tumor response semiquantitatively in patients with hepatocellular carcinoma (HCC). Carbon 34-35 ADAM metallopeptidase domain 17 Homo sapiens 144-148 28011206-5 2017 In addition, 6c inhibited self-induced Abeta1-42 aggregation and Cu2+-induced Abeta1-42 aggregation by 89.5% and 79.7% at 25muM respectively, as well as acted as a selective monoamine oxidase B inhibitor (IC50=0.29muM) and a selective biometal chelator. Carbon 13-15 monoamine oxidase B Homo sapiens 174-193 27978459-0 2017 Le Carbone, a charcoal supplement, modulates DSS-induced acute colitis in mice through activation of AMPKalpha and downregulation of STAT3 and caspase 3 dependent apoptotic pathways. Carbon 3-10 caspase 3 Mus musculus 143-152 27499100-1 2017 An aspargine-glycine-arginine (NGR) peptide modified single-walled carbon nanotubes (SWCNTs) system, developed by a simple non-covalent approach, could be loaded with the anticancer drug doxorubicin (DOX) and magnetic resonance imaging (MRI) contrast agent gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). Carbon 67-73 reticulon 4 receptor Homo sapiens 31-34 27941023-8 2017 Consistent with perturbation of the PDH bypass, crd1Delta cells grown on acetate as the sole carbon source exhibited decreased growth, decreased acetyl-CoA, and increased intracellular acetate levels resulting from decreased acetyl-CoA synthetase activity. Carbon 93-99 cardiolipin synthase Saccharomyces cerevisiae S288C 48-52 27991644-0 2017 Pulmonary surfactant protein SP-D opsonises carbon nanotubes and augments their phagocytosis and subsequent pro-inflammatory immune response. Carbon 44-50 surfactant protein D Homo sapiens 29-33 28115915-8 2017 RESULTS: Administration of low dose poly I:C upregulated the expression of PD-L1, induced neutrophilia and increased keratinocyte-derived chemokine (KC), macrophage inflammatory protein-1beta (MIP-1beta), and IL-6 in BALF. Carbon 43-44 chemokine (C-C motif) ligand 4 Mus musculus 154-191 28115915-8 2017 RESULTS: Administration of low dose poly I:C upregulated the expression of PD-L1, induced neutrophilia and increased keratinocyte-derived chemokine (KC), macrophage inflammatory protein-1beta (MIP-1beta), and IL-6 in BALF. Carbon 43-44 chemokine (C-C motif) ligand 4 Mus musculus 193-202 27916559-8 2017 The interference of rhinacanthin-C on the ABC drug transporters (P-gp, MRP1 and MRP2) was evaluated by substrate accumulation assay, using fluorescence spectroscopy technique. Carbon 33-34 ATP binding cassette subfamily C member 2 Homo sapiens 80-84 27846374-3 2017 Here we show that carbon-based nanodiamonds (NDs) coated with ubiquitin (Ub) bind to autophagy receptors (SQSTM1 [sequestosome 1], OPTN [optineurin], and CALCOCO2/NDP52 [calcium binding and coiled-coil domain 2]) and are then linked to MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3) for entry into the selective autophagy pathway. Carbon 18-24 sequestosome 1 Homo sapiens 106-112 27846374-3 2017 Here we show that carbon-based nanodiamonds (NDs) coated with ubiquitin (Ub) bind to autophagy receptors (SQSTM1 [sequestosome 1], OPTN [optineurin], and CALCOCO2/NDP52 [calcium binding and coiled-coil domain 2]) and are then linked to MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3) for entry into the selective autophagy pathway. Carbon 18-24 sequestosome 1 Homo sapiens 114-128 27846374-3 2017 Here we show that carbon-based nanodiamonds (NDs) coated with ubiquitin (Ub) bind to autophagy receptors (SQSTM1 [sequestosome 1], OPTN [optineurin], and CALCOCO2/NDP52 [calcium binding and coiled-coil domain 2]) and are then linked to MAP1LC3/LC3 (microtubule-associated protein 1 light chain 3) for entry into the selective autophagy pathway. Carbon 18-24 microtubule associated protein 1 light chain 3 alpha Homo sapiens 240-243 28204603-3 2017 Here we test how expression of the cyanobacterial, bifunctional fructose-1,6/sedoheptulose-1,7-bisphosphatase (FBP/SBPase) affects carbon assimilation and seed yield (SY) in a major crop (soybean, Glycine max). Carbon 131-137 fructose-1,6-bisphosphatase, chloroplastic Glycine max 111-114 29617103-0 2017 Immobilization of Glucose Oxidase on a Carbon Nanotubes/Dendrimer-Ferrocene Modified Electrode for Reagentless Glucose Biosensing. Carbon 39-45 hydroxyacid oxidase 1 Homo sapiens 18-33 27539821-6 2017 In particular, the novel use of engineered carbon nanotubes (CNTs) has garnered attention due to their specificity and sensitivity towards Hg2+ detection in solution. Carbon 43-49 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 139-142 27424262-7 2016 The resulting GOX-pFcAc conjugates generated over an order of magnitude increase in current generation efficiency and a 4-fold increase in maximum EBFC power density ( 1.7microWcm(-2)) with similar open circuit voltage (0.27V) compared to native GOX when physically adsorbed onto paddle-shaped electrodes made up of electrospun polyacrylonitrile fibers coated with gold nanoparticles and multi-wall carbon nanotubes. Carbon 399-405 hydroxyacid oxidase 1 Homo sapiens 14-17 27862752-4 2016 Here, we proposed to improve the affinity of a phage-selected bicyclic peptide inhibitor of coagulation factor XII (FXII) by screening variants with one or two carbon atoms inserted into different positions of the backbone, and thus tapping into a structural space that was not sampled by phage display. Carbon 160-166 coagulation factor XII Homo sapiens 92-114 27634155-1 2016 In this study, nanoscale zerovalent iron (NZVI) immobilized on biomass carbon was used for the high efficient removal of BDE 209. Carbon 71-77 homeobox D13 Homo sapiens 121-124 27634155-3 2016 The proposed removal mechanism included the adsorption of BDE 209 on the surface or interior of the biomass carbon NZVI (BC-NZVI) particles and the subsequent debromination of BDE 209 by NZVI while biomass carbon served as an electron shuttle. Carbon 108-114 homeobox D13 Homo sapiens 58-61 27523475-1 2016 Human hepatic flavin-containing monooxygenase 3 (hFMO3) catalyses the monooxygenation of carbon-bound reactive heteroatoms and plays an important role in the metabolism of drugs and xenobiotics. Carbon 89-95 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 6-47 27523475-1 2016 Human hepatic flavin-containing monooxygenase 3 (hFMO3) catalyses the monooxygenation of carbon-bound reactive heteroatoms and plays an important role in the metabolism of drugs and xenobiotics. Carbon 89-95 flavin containing dimethylaniline monoxygenase 3 Homo sapiens 49-54 27830757-3 2016 An amperometric glucose biosensor is fabricated by the immobilization of glucose oxidase (GOx) enzyme on Nafion solubilized Au/ MXene nanocomposite over glassy carbon electrode (GCE). Carbon 160-166 hydroxyacid oxidase 1 Homo sapiens 73-88 27830757-3 2016 An amperometric glucose biosensor is fabricated by the immobilization of glucose oxidase (GOx) enzyme on Nafion solubilized Au/ MXene nanocomposite over glassy carbon electrode (GCE). Carbon 160-166 hydroxyacid oxidase 1 Homo sapiens 90-93 27392334-7 2016 The changes in FSP indicate that severe impacts on how biological communities use carbon sources occur as a result of the human water management - too much focus on human needs - during intense climatic events. Carbon 82-88 C-X-C motif chemokine ligand 1 Homo sapiens 15-18 27723961-1 2016 We report an efficient method for fabricating flexible membranes of electrospun carbon nanofiber/tin(IV) sulfide (CNF@SnS2) core/sheath fibers. Carbon 80-86 NPHS1 adhesion molecule, nephrin Homo sapiens 114-117 27629250-1 2016 Various aryl-, alkenyl-, and/or alkyllithium species reacted smoothly with aryl and/or benzyl ethers with cleavage of the inert C-O bond to afford cross-coupled products, catalyzed by commercially available [Ni(cod)2 ] (cod=1,5-cyclooctadiene) catalysts with N-heterocyclic carbene (NHC) ligands. Carbon 128-129 COD2 Homo sapiens 211-216 27688173-3 2016 We fabricated the micro-biosensors by immobilizing a single-walled carbon nanotube-glucose oxidase (GOx)-glutaraldehyde (GA) bio-composite at the palladium nanoparticle (PdNPs) modified Pt electrode. Carbon 67-73 hydroxyacid oxidase 1 Homo sapiens 74-98 27688173-3 2016 We fabricated the micro-biosensors by immobilizing a single-walled carbon nanotube-glucose oxidase (GOx)-glutaraldehyde (GA) bio-composite at the palladium nanoparticle (PdNPs) modified Pt electrode. Carbon 67-73 hydroxyacid oxidase 1 Homo sapiens 100-103 27627613-1 2016 Here, we report a hierarchical Co3ZnC/carbon nanotube-inserted nitrogen-doped carbon concave-polyhedrons synthesized by direct pyrolysis of bimetallic zeolitic imidazolate framework precursors under a flow of Ar/H2 and subsequent calcination for both high-performance rechargeable Li-ion and Na-ion batteries. Carbon 38-44 ADP-ribosylhydrolase like 1 Homo sapiens 209-214 27627613-1 2016 Here, we report a hierarchical Co3ZnC/carbon nanotube-inserted nitrogen-doped carbon concave-polyhedrons synthesized by direct pyrolysis of bimetallic zeolitic imidazolate framework precursors under a flow of Ar/H2 and subsequent calcination for both high-performance rechargeable Li-ion and Na-ion batteries. Carbon 78-84 ADP-ribosylhydrolase like 1 Homo sapiens 209-214 27732857-4 2016 Notably, GPT2 engages activated glycolysis to drive the utilization of glutamine as a carbon source for TCA cycle anaplerosis in colon cancer cells. Carbon 86-92 glutamic--pyruvic transaminase 2 Homo sapiens 9-13 27608826-1 2016 Carbon nanofibers reinforced 3D porous carbon polyhedra network (e-CNF-PCP) was prepared through electrospinning and subsequent thermal treatment. Carbon 0-6 NPHS1 adhesion molecule, nephrin Homo sapiens 67-70 27608826-1 2016 Carbon nanofibers reinforced 3D porous carbon polyhedra network (e-CNF-PCP) was prepared through electrospinning and subsequent thermal treatment. Carbon 39-45 NPHS1 adhesion molecule, nephrin Homo sapiens 67-70 27608826-3 2016 The results show that the e-CNF-PCP exhibits a high electrosorption capacity of 16.98 mg g(-1) at 1.2 V in 500 mg l(-1) NaCl solution, which shows great improvement compared with those of electrospun carbon nanofibers and porous carbon polyhedra. Carbon 200-206 NPHS1 adhesion molecule, nephrin Homo sapiens 28-31 27417289-1 2016 A strategy utilizing elastin peptide macroporous cryogels to build highly flexible scaffolds to load carbon nanotubes, polypyrrole, and iron oxide magnetic nanoparticles, is presented. Carbon 101-107 elastin Homo sapiens 21-28 27285383-9 2016 End products indicated that RDX carbon became CO2, biomass, and a soluble, uncharacterized aqueous metabolite, determined using (14)C-labeled RDX. Carbon 32-38 radixin Homo sapiens 28-31 27285383-9 2016 End products indicated that RDX carbon became CO2, biomass, and a soluble, uncharacterized aqueous metabolite, determined using (14)C-labeled RDX. Carbon 32-38 radixin Homo sapiens 142-145 27566173-3 2016 We explored the disulfide conformational isomerization of the Cys14-Cys38 disulfide bond in bovine pancreatic trypsin inhibitor (BPTI), by performing an NMR line-shape analysis of its Cys carbon peaks. Carbon 188-194 spleen trypsin inhibitor I Bos taurus 129-133 27459476-0 2016 Diffusion of H2 and D2 Confined in Single-Walled Carbon Nanotubes: Quantum Dynamics and Confinement Effects. Carbon 49-55 relaxin 2 Homo sapiens 13-22 27459476-1 2016 We present quantum dynamics calculations of the diffusion constant of H2 and D2 along a single-walled carbon nanotube at temperatures between 50 and 150 K. We calculate the respective diffusion rates in the low-pressure limit by adapting well-known approaches and methods from the chemical dynamics field using two different potential energy surfaces to model the C-H interaction. Carbon 102-108 relaxin 2 Homo sapiens 70-79 27459476-1 2016 We present quantum dynamics calculations of the diffusion constant of H2 and D2 along a single-walled carbon nanotube at temperatures between 50 and 150 K. We calculate the respective diffusion rates in the low-pressure limit by adapting well-known approaches and methods from the chemical dynamics field using two different potential energy surfaces to model the C-H interaction. Carbon 364-365 relaxin 2 Homo sapiens 70-79 27560137-2 2016 The MTHFR and TS protein were crucial factor in one-carbon metabolism. Carbon 52-58 methylenetetrahydrofolate reductase Homo sapiens 4-9 27597842-4 2016 Our results are consistent with the hypothesis - previously developed based on (14)C incorporation experiments with mixed-species enrichments from Mediterranean seafloor brines - that KB1 has adapted its proteins to elevated intracellular salinity, but at the same time KB1 apparently imports glycine betaine; this compatible solute is potentially not limited to osmoregulation but could also serve as a carbon and energy source. Carbon 404-410 folate receptor 1 pseudogene 1 Homo sapiens 184-187 27237045-0 2016 Carbon Flux Trapping: Highly Efficient Production of Polymer-Grade d-Lactic Acid with a Thermophilic d-Lactate Dehydrogenase. Carbon 0-6 lactate dehydrogenase D Homo sapiens 101-124 27492274-0 2016 Direct carbon-carbon bond formation via reductive soft enolization: a syn-selective Mannich addition of alpha-iodo thioesters. Carbon 7-13 synemin Homo sapiens 70-73 27492274-0 2016 Direct carbon-carbon bond formation via reductive soft enolization: a syn-selective Mannich addition of alpha-iodo thioesters. Carbon 14-20 synemin Homo sapiens 70-73 27689010-9 2016 Mass spectrometry analysis showed that the flux of carbon from [U-(13)C]glucose and/or [U-(13)C]alpha-ketoisocaproic acid (KIC) into short chain acyl-CoAs in cells with hydroxycitrate-inhibited ATP citrate lyase or in the cell line with stable severe (>90%) shRNA knockdown of ATP citrate lyase was similar to the controls. Carbon 51-57 ATP citrate lyase Homo sapiens 194-211 27689010-9 2016 Mass spectrometry analysis showed that the flux of carbon from [U-(13)C]glucose and/or [U-(13)C]alpha-ketoisocaproic acid (KIC) into short chain acyl-CoAs in cells with hydroxycitrate-inhibited ATP citrate lyase or in the cell line with stable severe (>90%) shRNA knockdown of ATP citrate lyase was similar to the controls. Carbon 51-57 ATP citrate lyase Homo sapiens 280-297 27241289-0 2016 Entrapping cross-linked glucose oxidase aggregates within a graphitized mesoporous carbon network for enzymatic biofuel cells. Carbon 83-89 hydroxyacid oxidase 1 Homo sapiens 24-39 27241289-1 2016 This paper reports a novel method for producing glucose oxidase-nanocomposites by entrapping cross-linked glucose oxidase (GOx) aggregates within a graphitized mesoporous carbon (GMC) network. Carbon 171-177 hydroxyacid oxidase 1 Homo sapiens 48-63 27241289-1 2016 This paper reports a novel method for producing glucose oxidase-nanocomposites by entrapping cross-linked glucose oxidase (GOx) aggregates within a graphitized mesoporous carbon (GMC) network. Carbon 171-177 hydroxyacid oxidase 1 Homo sapiens 106-121 27241289-1 2016 This paper reports a novel method for producing glucose oxidase-nanocomposites by entrapping cross-linked glucose oxidase (GOx) aggregates within a graphitized mesoporous carbon (GMC) network. Carbon 171-177 hydroxyacid oxidase 1 Homo sapiens 123-126 27145098-11 2016 Analysis of marker genes from sugar signalling pathways (SnRK1 and Tor) suggest that ara1-1 misinterprets its carbon energy status. Carbon 110-116 arabinose kinase Arabidopsis thaliana 85-91 27399338-3 2016 The self-association behavior of TBP in various alkane diluents of different chain lengths (8, 12, and 16 carbons) and a branched alkane (iso-octane) was investigated by Fourier transform infrared spectroscopic measurements. Carbon 106-113 TATA-box binding protein Homo sapiens 33-36 27261460-7 2016 Finally, using both co-immunoprecipitation and bimolecular fluorescence complementation, we demonstrated the interaction of Rod1 with Hxt6 and showed that the localization of the Rod1-Hxt6 complex at the plasma membrane is affected by carbon source and is reduced upon overexpression of SNF1 and BMH2. Carbon 235-241 hexose transporter HXT6 Saccharomyces cerevisiae S288C 134-138 27261460-7 2016 Finally, using both co-immunoprecipitation and bimolecular fluorescence complementation, we demonstrated the interaction of Rod1 with Hxt6 and showed that the localization of the Rod1-Hxt6 complex at the plasma membrane is affected by carbon source and is reduced upon overexpression of SNF1 and BMH2. Carbon 235-241 hexose transporter HXT6 Saccharomyces cerevisiae S288C 184-188 27340753-3 2016 Furthermore, the products bearing the TMS group can be transformed into the valuable compounds with the CF2 fragment via the carbon-carbon bond forming reactions. Carbon 125-131 ATPase H+ transporting accessory protein 1 Homo sapiens 104-107 27340753-3 2016 Furthermore, the products bearing the TMS group can be transformed into the valuable compounds with the CF2 fragment via the carbon-carbon bond forming reactions. Carbon 132-138 ATPase H+ transporting accessory protein 1 Homo sapiens 104-107 26812179-2 2016 The ether oxygen is linked to the (CF2) carbon atom, with a C-O distance of 2.908 A. Carbon 40-46 ATPase H+ transporting accessory protein 1 Homo sapiens 35-38 27208123-4 2016 strain DL-8 can transform CDHB into 2-amino-5-chlorophenol (2A5CP), which it then utilizes as a carbon source for growth. Carbon 96-102 cadherin 12 Homo sapiens 26-30 27347216-7 2016 Among many genes with concerted expression response to individual antitumor agents were genes encoding DNA methyltransferases DNMT1, DNMT3A, and DNMT3B, epigenetic and DNA repair factors MGMT, GADD45A, and MBD1, and one-carbon metabolism pathway members MTHFD1, TYMS, DHFR, MTR, MAT2A, SLC19A1, ATIC, and GART. Carbon 220-226 O-6-methylguanine-DNA methyltransferase Homo sapiens 187-191 27376029-12 2016 Several clinically available chemotherapeutic drugs (carboplatin, paclitaxel, and etoposide) and drugs at the developmental stage (Wee-1 and heat shock protein 90 inhibitors) show a sensitizing effect on tumor cells treated with carbon ions. Carbon 229-235 WEE1 G2 checkpoint kinase Homo sapiens 131-136 26605808-10 2016 An increase in C (p = 0.007) and a decrease in T:C ratio (p = 0.003) was observed from BS4 to BS5. Carbon 15-16 negative regulator of ubiquitin like proteins 1 Homo sapiens 87-90 26605808-10 2016 An increase in C (p = 0.007) and a decrease in T:C ratio (p = 0.003) was observed from BS4 to BS5. Carbon 49-50 negative regulator of ubiquitin like proteins 1 Homo sapiens 87-90 27017606-9 2016 COT administration reduced lipid accumulation in the liver, ameliorated the pathological changes, and lessened liver injury, the levels of TG, TC, and non-HDL-C in plasma were decreased significantly, and COT led to a significant increase in plasma HDL-C and apolipoprotein A (apoA1). Carbon 0-1 apolipoprotein A-I Mus musculus 277-282 27067917-4 2016 In this study, we compared structure-activity relationships (SAR) of 14 phthalates varied in carbon atoms in alcohol moiety to inhibit human HSD3B1 in COS1 and CYP19A1 in JEG-3 cells. Carbon 93-99 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Homo sapiens 141-147 27130136-0 2016 Corrigendum to "A high-performance glucose biosensor using covalently immobilised glucose oxidase on a poly(2,6-diaminopyridine)/carbon nanotube electrode". Carbon 129-135 hydroxyacid oxidase 1 Homo sapiens 82-97 27130136-1 2016 A highly-sensitive glucose biosensor amenable to ultraminiaturisation was fabricated by immobilization of glucose oxidase (GOX), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWCNT/GCE). Carbon 175-181 hydroxyacid oxidase 1 Homo sapiens 106-121 27130136-1 2016 A highly-sensitive glucose biosensor amenable to ultraminiaturisation was fabricated by immobilization of glucose oxidase (GOX), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWCNT/GCE). Carbon 175-181 hydroxyacid oxidase 1 Homo sapiens 123-126 27130136-1 2016 A highly-sensitive glucose biosensor amenable to ultraminiaturisation was fabricated by immobilization of glucose oxidase (GOX), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWCNT/GCE). Carbon 198-204 hydroxyacid oxidase 1 Homo sapiens 106-121 27130136-1 2016 A highly-sensitive glucose biosensor amenable to ultraminiaturisation was fabricated by immobilization of glucose oxidase (GOX), onto a poly(2,6-diaminopyridine)/multi-walled carbon nanotube/glassy carbon electrode (poly(2,6-DP)/MWCNT/GCE). Carbon 198-204 hydroxyacid oxidase 1 Homo sapiens 123-126 26992523-0 2016 Fluorescent probes for "off-on" highly sensitive detection of Hg2+ and L-cysteine based on nitrogen-doped carbon dots. Carbon 106-112 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 62-65 27010865-0 2016 Controlling the Direction of the Molecular Axis of Rod-Shaped Binuclear Ruthenium Complexes on Single-Walled Carbon Nanotubes. Carbon 109-115 kinetochore associated 1 Homo sapiens 51-54 27483912-1 2016 In our present study, polypyrrole-1 (PPy1), polypyrrole-2 (PPy2), and polypyrrole-2/multi wall carbon nanotube composite film (PPy2/MWCNT) were proposed as counter electrodes (CEs) in dye-sensitized solar cells (DSSCs) to replace the precious Pt CE. Carbon 95-101 pancreatic polypeptide 2, pseudogene Homo sapiens 127-131 27152812-1 2016 The small spin-orbit interaction of carbon atoms in graphene promises a long spin diffusion length and the potential to create a spin field-effect transistor. Carbon 36-42 spindlin 1 Homo sapiens 10-14 27152812-1 2016 The small spin-orbit interaction of carbon atoms in graphene promises a long spin diffusion length and the potential to create a spin field-effect transistor. Carbon 36-42 spindlin 1 Homo sapiens 77-81 27152812-1 2016 The small spin-orbit interaction of carbon atoms in graphene promises a long spin diffusion length and the potential to create a spin field-effect transistor. Carbon 36-42 spindlin 1 Homo sapiens 77-81 33465866-4 2016 The coating is a stable carbon-based plasma polymer layer that increased surface wettability by 28%, improved surface elasticity to the range exhibited by natural bone, and additionally covalently bound the extracellular matrix protein, tropoelastin, in an active conformation. Carbon 24-30 elastin Homo sapiens 237-249 26732296-4 2016 Here, we show that in vitro-synchronized cultured cells exhibit BMAL1-dependent oscillation in mitochondrial respiratory activity, which occurs irrespective of the cell type tested, the protocol of synchronization used and the carbon source in the medium. Carbon 227-233 aryl hydrocarbon receptor nuclear translocator like Homo sapiens 64-69 27079438-6 2016 Importantly, the combined adjuvant of poly(I:C) plus LAG-3-Ig downregulated expressions of PD-1, LAG-3, and TIGIT on P1A-specific T cells, indicating prevention of T cell exhaustion. Carbon 45-46 T cell immunoreceptor with Ig and ITIM domains Mus musculus 108-113 26838838-1 2016 Hybridized carbon nanofibers containing calcium phosphate nanoparticles (CNF/CaP) were investigated as osteocompatible nanofillers for epoxy resin. Carbon 11-17 NPHS1 adhesion molecule, nephrin Homo sapiens 73-76 27001419-6 2016 RESULTS: ptxA (-), ptxB (-), as well as ptxA (-) , ptxB (-) double-deletion mutants all had more extended lag phase and lower growth yield than wild-type strain UA159 when grown in the medium using L-ascorbate as the sole carbon source. Carbon 222-228 PTS transporter subunit EIIA Streptococcus mutans UA159 40-44 27001419-11 2016 CONCLUSIONS: The ptxA and ptxB genes are involved in the growth, aciduricity, acidogenesis, and formation of biofilms and EPS of S. mutans when L-ascorbate is the sole carbon source. Carbon 168-174 PTS transporter subunit EIIA Streptococcus mutans UA159 17-21 26969728-6 2016 Because 13-LOX pathway products comprise compounds involved in insect deterrence and pathogen defense (volatile aldehydes and oxylipins), a mechanism of unmolested nitrogen and carbon relocation is suggested that occurs from leaves to seeds and roots during fall. Carbon 177-183 lysyl oxidase Homo sapiens 11-14 26856208-2 2016 The synthesis features the stereoselective Stille cross-coupling reaction to set up the whole carbon framework, aldol condensation to construct the highly substituted conjugated diene, non-Evans syn aldol, CBS reduction, Hantzsch"s thiazole synthesis, Horner-Wadsworth-Emmons reaction, and Shiina"s macrolactonization. Carbon 94-100 synemin Homo sapiens 4-7 26680361-2 2016 FAS synthesizes long-chain fatty acids from three substrates: acetyl-CoA as a primer, malonyl-CoA as a 2 carbon donor, and NADPH for reduction. Carbon 105-111 fatty acid synthase Homo sapiens 0-3 26880641-19 2016 Because LSD1 can regulate gene expression this suggests that folate may play a more important role than simply serving as a carrier of one-carbon units and be a factor in other diseases associated with low folate. Carbon 139-145 lysine demethylase 1A Homo sapiens 8-12 26842424-3 2016 The stereogenic carbons were elaborated by desymmetrization for C12, allylation for C13, vanadyl-induced epoxidation for C16, Zn(BH4)2 reduction for C17, a chiral building block for C18 and C24, Shi epoxidation for C20 and C21, Myers" alkylation for C22, and thermodynamic control for C25. Carbon 16-23 homeobox C13 Homo sapiens 84-87 26609931-1 2016 A molecule with a pi conjugated backbone built from aromatic thiophene and dialkoxyphenylene units and substituted imidazolium groups (TPO) is designed to obtain ultra-stable single walled carbon nanotube (SWCNT) dispersion in aqueous medium. Carbon 189-195 thyroid peroxidase Homo sapiens 135-138 26678838-8 2016 The growth assays demonstrated that the growth of the eprS mutant was somewhat lower than that of the wild-type strain in a minimal medium containing BSA as the sole carbon and nitrogen source. Carbon 166-172 glutamyl-prolyl-tRNA synthetase Mus musculus 54-58 26657319-1 2016 Transition metal-nitrogen/carbon (M-N/C, M = Fe, Co) catalysts are synthesized using environmentally friendly histidine-tag-rich elastin protein beads, metal sulfate and water soluble carbon nanotubes followed by post-annealing and acid leaching processes. Carbon 26-32 elastin Homo sapiens 129-136 26751683-7 2016 Moreover, by studying the interactions between saturated fatty acids (SFA) and the Shaker KV channel, our study confirmed an increased conformational flexibility in the polyunsaturated carbon tails compared to saturated carbon chains, which may explain the specificity of PUFA action on channel proteins. Carbon 185-191 pumilio RNA binding family member 3 Homo sapiens 272-276 28132465-5 2016 In other organisms AOX activity is important for maintaining metabolic homeostasis (carbon metabolism, cell redox state and energy demand) and ROS homeostasis. Carbon 84-90 acyl-CoA oxidase 1 Homo sapiens 19-22 26602813-0 2015 Freestanding carbon-coated CNT/Sn(O2) coaxial sponges with enhanced lithium-ion storage capability. Carbon 13-19 immunoglobulin kappa variable 1D-39 Homo sapiens 31-36 26668261-6 2015 Due to a lack of extracellular lipase, the gspD mutant, the gspE mutant, and a lipA deletion strain are incapable of growth on long-chain fatty acids as a sole source of carbon, while their growth characteristics are indistinguishable from those of the wild-type strain in nutrient-rich broth. Carbon 170-176 lysosomal acid lipase A Mus musculus 79-83 26658504-12 2015 Furthermore, repeated administration of poly I:C to C57BL/6 mice over an 8-day period caused leukocytic infiltration and caspase-3 activation in the LAC, antinuclear antibody production, and impaired tear secretion. Carbon 47-48 caspase 3 Mus musculus 121-130 26551320-0 2015 Electrochemically Functionalized Seamless Three-Dimensional Graphene-Carbon Nanotube Hybrid for Direct Electron Transfer of Glucose Oxidase and Bioelectrocatalysis. Carbon 69-75 hydroxyacid oxidase 1 Homo sapiens 124-139 26551320-1 2015 Three-dimensional seamless chemical vapor deposition (CVD) grown graphene-carbon nanotubes (G-CNT) hybrid film has been studied for its potential in achieving direct electron transfer (DET) of glucose oxidase (GOx) and its bioelectrocatalytic activity in glucose detection. Carbon 74-80 hydroxyacid oxidase 1 Homo sapiens 193-208 26551320-1 2015 Three-dimensional seamless chemical vapor deposition (CVD) grown graphene-carbon nanotubes (G-CNT) hybrid film has been studied for its potential in achieving direct electron transfer (DET) of glucose oxidase (GOx) and its bioelectrocatalytic activity in glucose detection. Carbon 74-80 hydroxyacid oxidase 1 Homo sapiens 210-213 26631379-5 2015 Like its human counterpart, the Lst7/Lst4 complex relocates to the vacuolar membrane in response to nutrient starvation, most notably in carbon starvation. Carbon 137-143 Lst7p Saccharomyces cerevisiae S288C 32-36 26447683-7 2015 This reveals the importance of NiR in primary nitrogen assimilation and how modification of this key enzyme affects both the nitrogen and carbon metabolism of tobacco plants. Carbon 138-144 nitrite reductase 1 Arabidopsis thaliana 31-34 26645158-0 2015 Targeting of Carbon Ion-Induced G2 Checkpoint Activation in Lung Cancer Cells Using Wee-1 Inhibitor MK-1775. Carbon 13-19 WEE1 G2 checkpoint kinase Homo sapiens 84-89 28793693-7 2015 Among them, the Pd/TinO2n-1 catalyst showed a very promising stability compared to carbon-supported Pd samples in an accelerated degradation test of 1000 potential cycles. Carbon 83-89 mex-3 RNA binding family member D Homo sapiens 19-23 26278169-0 2015 Interfacial electron transfer of glucose oxidase on poly(glutamic acid)-modified glassy carbon electrode and glucose sensing. Carbon 88-94 hydroxyacid oxidase 1 Homo sapiens 33-48 26278169-1 2015 The interfacial electron transfer of glucose oxidase (GOx) on a poly(glutamic acid)-modified glassy carbon electrode (PGA/GCE) was investigated. Carbon 100-106 hydroxyacid oxidase 1 Homo sapiens 37-52 26278169-1 2015 The interfacial electron transfer of glucose oxidase (GOx) on a poly(glutamic acid)-modified glassy carbon electrode (PGA/GCE) was investigated. Carbon 100-106 hydroxyacid oxidase 1 Homo sapiens 54-57 26978943-8 2015 The regression equation is V0/V = 1.309 13 + 3.37c, where c is Hg2+ concentration, and V0 is the voltage value for the blank case. Carbon 49-50 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 63-66 26169151-0 2015 Innate immune humoral factors, C1q and factor H, with differential pattern recognition properties, alter macrophage response to carbon nanotubes. Carbon 128-134 complement factor H Homo sapiens 39-47 26437241-3 2015 We found that miR-22 was upregulated in lung myeloid dendritic cells (mDCs) of smokers with emphysema and antigen-presenting cells (APCs) of mice exposed to smoke or nanoparticulate carbon black (nCB) through a mechanism that involved the transcription factor NF-kappaB. Carbon 182-188 microRNA 22 Mus musculus 14-20 26272622-0 2015 MyD88 mediates in vivo effector functions of alveolar macrophages in acute lung inflammatory responses to carbon nanotube exposure. Carbon 106-112 myeloid differentiation primary response gene 88 Mus musculus 0-5 26344174-3 2015 In this work, the rapid and controllable spin-spray layer-by-layer (SSLbL) method is used to generate high quality networks of 1D nanomaterials: single-walled carbon nanotubes (SWNT) and vanadium pentoxide (V2O5) nanowires for anode and cathode electrodes, respectively. Carbon 159-165 spindlin 1 Homo sapiens 41-45 26505478-7 2015 Comprehensive chemokine analysis showed that, compared with poly(I:C) alone, co-stimulation of BEAS-2B cells with IL-17A and poly(I:C) strongly induced production of such neutrophil chemoattractants as CXC chemokine ligand (CXCL)8, growth-related oncogene (GRO), and CXCL1. Carbon 0-1 interleukin 17A Homo sapiens 114-120 26457527-1 2015 Porcine pancreatic carboxypeptidase B (EC 3.4.23.6) was complexed with a stable transition-state analogue, N-sulfamoyl-L-arginine, in which an S atom imitates the sp(3)-hybridized carbon in the scissile-bond surrogate. Carbon 180-186 carboxypeptidase B1 Homo sapiens 8-37 25959927-0 2015 Quantitative electrochemical detection of cathepsin B activity in breast cancer cell lysates using carbon nanofiber nanoelectrode arrays toward identification of cancer formation. Carbon 99-105 cathepsin B Homo sapiens 42-53 25959927-1 2015 UNLABELLED: The proteolytic activity of cathepsin B in complex breast cell lysates has been measured with alternating current voltammetry (ACV) using ferrocene (Fc)-labeled-tetrapeptides immobilized on nanoelectrode arrays (NEAs) fabricated with vertically aligned carbon nanofibers (VACNFs). Carbon 265-271 cathepsin B Homo sapiens 40-51 26338199-6 2015 RT-PCR Array analysis showed that carbon ion beam combined with CDDP significantly induced apoptosis-related Cytochrome c, almost completely eliminated expression of the CSC markers CD44 and ESA, and significantly inhibited angiogenesis, and metastasis-related HIF1alpha and CD26 compared to carbon ion beam alone, X-ray alone, or X-ray combined with CDDP. Carbon 34-40 CD44 molecule (Indian blood group) Homo sapiens 182-186 26107993-3 2015 When conjugated with fluorescent carbon nanodots (CDots) it could freely enter multiple living tumor cell lines (HepG2, MCF-7, H1299, and HeLa), whose growth it inhibited by targeting hnRNP A2/B1. Carbon 33-39 heterogeneous nuclear ribonucleoprotein A2/B1 Rattus norvegicus 184-195 26025589-1 2015 Catalytic oxidation of multi-walled carbon nanotubes (MWNCTs) with some noble metal nanoparticles was observed by environmental transmission electron microscopy (E-TEM). Carbon 36-42 MFT2 Homo sapiens 164-167 26234706-9 2015 We propose that root-expressed vacuolar SWEET2 modulates sugar secretion, possibly by reducing the availability of glucose sequestered in the vacuole, thereby limiting carbon loss to the rhizosphere. Carbon 168-174 Nodulin MtN3 family protein Arabidopsis thaliana 40-46 26371657-4 2015 The spin tune is deduced from the up-down asymmetry of deuteron-carbon scattering. Carbon 64-70 spindlin 1 Homo sapiens 4-8 26138361-2 2015 This process allows syn substituents to be established stereospecifically on the 2-carbon bridge connecting the ketone carbonyl carbons, and the formation of one carbon-carbon and two carbon-oxygen bonds. Carbon 83-89 synemin Homo sapiens 20-23 26138361-2 2015 This process allows syn substituents to be established stereospecifically on the 2-carbon bridge connecting the ketone carbonyl carbons, and the formation of one carbon-carbon and two carbon-oxygen bonds. Carbon 128-135 synemin Homo sapiens 20-23 26249707-7 2015 There is a conserved aspartic acid residue in both structures, which has been shown to be important for hydration of the C=C bond during the release of unsaturated galacturonic acid by YteR. Carbon 121-122 unsaturated rhamnogalacturonyl hydrolase Bacillus subtilis subsp. subtilis str. 168 185-189 26249707-7 2015 There is a conserved aspartic acid residue in both structures, which has been shown to be important for hydration of the C=C bond during the release of unsaturated galacturonic acid by YteR. Carbon 123-124 unsaturated rhamnogalacturonyl hydrolase Bacillus subtilis subsp. subtilis str. 168 185-189 26206248-9 2015 Taken together, results demonstrate that modulation of primary carbon metabolism and other pathways by AtMYB12 in tomato may lead to sufficient substrate supply for enhanced content of phenolics in general and flavonols in particular. Carbon 63-69 myb domain protein 12 Arabidopsis thaliana 103-110 26061638-5 2015 Pt/Nb-SnO2 loose-tubes constitute a mitigation strategy for two known degradation mechanisms in PEMFC: corrosion of the carbon support at the cathode, and dissolution of Pt at high cell voltages. Carbon 120-126 strawberry notch homolog 2 Homo sapiens 6-9 25982115-5 2015 We propose that SCF(Ucc1)-mediated regulation of citrate synthase acts as a metabolic switch for the glyoxylate cycle in response to changes in carbon source, thereby ensuring metabolic versatility and flexibility. Carbon 144-150 KIT ligand Homo sapiens 16-19 25934454-0 2015 Carbon nanotubes enhance intercalated disc assembly in cardiac myocytes via the beta1-integrin-mediated signaling pathway. Carbon 0-6 integrin subunit beta 1 Homo sapiens 80-94 25648260-4 2015 Cross-talk was observed between one-carbon and xenobiotic pathways in breast cancer (RFC 80 G>A, COMT H108L and TYMS 5"-UTR 28 bp tandem repeat) and SLE (CYP1A1 m1, MTRR 66 A>G and GSTT1). Carbon 36-42 glutathione S-transferase theta 1 Homo sapiens 181-186 25648260-5 2015 Gene-gene interactions within one-carbon metabolic pathway were observed in CAD (GCPII 1561 C>T, SHMT 1420 C>T and MTHFR 677 C>T) and PD (cSHMT 1420 C>T, MTRR 66 A>G and RFC1 80 G>A). Carbon 34-40 replication factor C subunit 1 Homo sapiens 170-174 25721554-8 2015 Applicability to renewable blood glucose testing, epidermal glucose monitoring, and on-leaf phenol detection are demonstrated in connection to glucose oxidase and tyrosinase-based carbon inks. Carbon 180-186 tyrosinase Homo sapiens 163-173 25999742-2 2015 Serine hydroxymethyltransferase (SHMT) directs serine to the metabolism of one-carbon unit and the synthesis of thymidilate as a key factor in this metabolic shift. Carbon 79-85 serine hydroxymethyltransferase 2 Homo sapiens 33-37 25865711-5 2015 Computational fluid dynamics simulations of the gas diffusion processes revealed the homogeneous distributions of the carbon-source-gas concentration, pressure, and velocity near the substrate surface at alpha = 0 , which were the important factors in achieving the mass-transport-limited uniform CNF growth. Carbon 118-124 NPHS1 adhesion molecule, nephrin Homo sapiens 297-300 25943704-0 2015 Direct electrochemistry of glucose oxidase on novel free-standing nitrogen-doped carbon nanospheres@carbon nanofibers composite film. Carbon 81-87 hydroxyacid oxidase 1 Homo sapiens 27-42 25943704-0 2015 Direct electrochemistry of glucose oxidase on novel free-standing nitrogen-doped carbon nanospheres@carbon nanofibers composite film. Carbon 100-106 hydroxyacid oxidase 1 Homo sapiens 27-42 25943704-1 2015 We have proposed a novel free-standing nitrogen-doped carbon nanospheres@carbon nanofibers (NCNSs@CNFs) composite film with high processability for the investigation of the direct electron transfer (DET) of glucose oxidase (GOx) and the DET-based glucose biosensing. Carbon 54-60 hydroxyacid oxidase 1 Homo sapiens 207-222 25943704-1 2015 We have proposed a novel free-standing nitrogen-doped carbon nanospheres@carbon nanofibers (NCNSs@CNFs) composite film with high processability for the investigation of the direct electron transfer (DET) of glucose oxidase (GOx) and the DET-based glucose biosensing. Carbon 54-60 hydroxyacid oxidase 1 Homo sapiens 224-227 25943704-1 2015 We have proposed a novel free-standing nitrogen-doped carbon nanospheres@carbon nanofibers (NCNSs@CNFs) composite film with high processability for the investigation of the direct electron transfer (DET) of glucose oxidase (GOx) and the DET-based glucose biosensing. Carbon 73-79 hydroxyacid oxidase 1 Homo sapiens 207-222 25451299-6 2015 Moreover, poIFIT3 can significantly enhance poly(I:C)-induced IFN-beta promoter activity through both IRF3- and NF-kappaB-mediated signaling pathways. Carbon 51-53 interferon beta 1 Sus scrofa 62-70 26504953-0 2015 Polycyclodextrin and Carbon Nanotubes as Composite for Tyrosinase Immobilization and Its Superior Electrocatalytic Activity Towards Butylparaben an Endocrine Disruptor. Carbon 21-27 tyrosinase Homo sapiens 55-65 26504953-1 2015 We developed a protocol for the immobilization of tyrosinase (Tyr) on the composite of polycyclodextrin polymer (CDP) and carbon nanotubes for the detection of an endocrine disruptor, i.e., butylparaben (BP). Carbon 122-128 tyrosinase Homo sapiens 50-60 26504953-1 2015 We developed a protocol for the immobilization of tyrosinase (Tyr) on the composite of polycyclodextrin polymer (CDP) and carbon nanotubes for the detection of an endocrine disruptor, i.e., butylparaben (BP). Carbon 122-128 tyrosinase Homo sapiens 62-65 26504953-3 2015 The conducting film of cross-linked CDP and carbon nanotubes, displays excellent matrix capabilities for Tyr immobilization. Carbon 44-50 tyrosinase Homo sapiens 105-108 25798528-3 2015 Compound 1 represents the first limonoid found with a novel 7-oxabicyclo[2.2.1]heptane moiety produced by incorporating C-11 and C-14 via an oxygen atom. Carbon 0-1 RNA polymerase III subunit K Homo sapiens 120-124 27877775-7 2015 The reason is mainly attributed to the barrier effect of the unburned graphene sheets, which protects by the decomposition products of PEPA and TDI, promotes the formation of graphitized carbon and inhibits the heat and gas release. Carbon 187-193 carnosine dipeptidase 2 Homo sapiens 135-139 26029442-3 2015 For both substituents, the H atom attached to the central C atom of the isopropyl group is approximately syn to the S atom in the attached ring. Carbon 58-59 synemin Homo sapiens 105-108 25707988-0 2015 Oxidation of CO on a carbon-based material composed of nickel hydroxide and hydroxyl graphene oxide, (Ni4(OH)3-hGO)--a first-principles calculation. Carbon 21-27 homogentisate 1,2-dioxygenase Homo sapiens 111-114 25704034-1 2015 Pyrolysis of base metal salt loaded microcrystalline cellulose spheres gives a facile access to carbon-supported base metal nanoparticles, which have been characterized with temperature-dependent XRD, SEM, TEM, ICP-MS and elemental analysis. Carbon 96-102 MFT2 Homo sapiens 206-209 25604861-11 2015 Our study suggests that these MTHFR and MTR SNPs may act as effect modifiers, highlighting their biological significance in the association between Mediterranean diet, the one-carbon metabolism pathway and BC. Carbon 176-182 methylenetetrahydrofolate reductase Homo sapiens 30-35 25351293-16 2015 Our data suggest that Poly (I:C) decreases in cerebral I/R injury via TLR3 which associates with Fas, thereby preventing the interaction of Fas and FADD, as well as microglial cell caspase-3 and -8 activities. Carbon 30-31 caspase 3 Mus musculus 181-197 32264487-6 2015 We also report the direct electrochemistry of glucose oxidase (GOx) on 1D HAp-on-2D RGO nanocomposite-modified glassy carbon electrode (GCE) for glucose sensing. Carbon 118-124 hydroxyacid oxidase 1 Homo sapiens 46-61 32264487-6 2015 We also report the direct electrochemistry of glucose oxidase (GOx) on 1D HAp-on-2D RGO nanocomposite-modified glassy carbon electrode (GCE) for glucose sensing. Carbon 118-124 hydroxyacid oxidase 1 Homo sapiens 63-66 24632615-10 2015 Under low glucose, all three carbons from (13)C3-lactate appeared in the PEP pool, further supporting a conversion of lactate to pyruvate, via pyruvate carboxylase to oxaloacetate, and via PCK2 to phosphoenolpyruvate. Carbon 29-36 phosphoenolpyruvate carboxykinase 2, mitochondrial Homo sapiens 189-193 32261990-4 2015 The immobilized GOx displayed a pair of well-defined quasi-reversible redox peaks with a potential of -0.39 V (vs. SCE) and an ideal electron transfer rate constant (ks) of 3.0 s-1 in PBS solution (0.1 M, pH = 5.5) on the PANI microtubes instead of a bare glass carbon electrode (GCE). Carbon 262-268 hydroxyacid oxidase 1 Homo sapiens 16-19 25594676-2 2015 The in situ generated syn-Mannich adduct obtained via proline catalysis acts as a four-atom component, and Corey"s sulfur ylide or ethyl bromoacetate acts as a one-atom carbon source to construct pyrrolidine units in a highly enantio- and diastereoselective manner. Carbon 169-175 synemin Homo sapiens 22-25 25612818-0 2015 Biomolecular recognition ability of RecA proteins for DNA on single-walled carbon nanotubes. Carbon 75-81 RAD51 recombinase Homo sapiens 36-40 25470755-0 2015 The discoloration of the Taj Mahal due to particulate carbon and dust deposition. Carbon 54-60 TNF receptor superfamily member 19 Homo sapiens 25-28 25499878-3 2015 The remit of an Isotope Chemistry group varies from company to company, but often includes the synthesis of compounds labeled with radioisotopes, especially H-3 and C-14 and occasionally I-125, and stable isotopes, especially H-2, C-13, and N-15. Carbon 24-25 homeobox C13 Homo sapiens 231-235 25572484-7 2015 The relation between plasma HDL-C level and risk of postprocedural cTnI elevation above 1xULN, 3xULN, and 5xULN was modified by LDL-C level (all P for interaction <0.05). Carbon 31-33 troponin I3, cardiac type Homo sapiens 67-71 25496025-3 2015 A [2,3]- or [1,2]-rearrangement occurs to give a 2-allylpyrrolidinyl-2-carbimine intermediate which undergoes Cu(OTf)2 catalyzed aza-Friedel-Crafts cyclization to finish a highly functionalized tricyclic system decorated with a synthetically difficult quaternary carbon center, a sulfonamide group, and an allyl segment. Carbon 263-269 POU class 2 homeobox 2 Homo sapiens 113-118 24972172-9 2015 Recommended QSAR model showed that the highest f(0) value of main-chain carbons (f(0)x) is more closely related to lnk" than other quantum descriptors. Carbon 72-79 SH2B adaptor protein 3 Homo sapiens 115-118 25578269-3 2015 Phenylalanine ammonia-lyase (PAL) is the first committed enzyme in the pathway; it diverts the central flux of carbon from the primary metabolism to the synthesis of myriad phenolics. Carbon 111-117 peptidylglycine alpha-amidating monooxygenase Homo sapiens 0-27 25578269-3 2015 Phenylalanine ammonia-lyase (PAL) is the first committed enzyme in the pathway; it diverts the central flux of carbon from the primary metabolism to the synthesis of myriad phenolics. Carbon 111-117 peptidylglycine alpha-amidating monooxygenase Homo sapiens 29-32 25480007-0 2015 Response of nitrate reductase activity and NIA genes expression in roots of Arabidopsis hxk1 mutant treated with selected carbon and nitrogen metabolites. Carbon 122-128 hexokinase 1 Arabidopsis thaliana 88-92 25461681-4 2015 In this study, we found that multiwalled carbon nanotubes (MWCNTs) reduced transport activity and expression of ABC transporters including ABCB1/Pgp and ABCC4/MRP4 in human colon adenocarcinoma Caco-2 cells. Carbon 41-47 ATP binding cassette subfamily C member 4 Homo sapiens 153-158 25461681-4 2015 In this study, we found that multiwalled carbon nanotubes (MWCNTs) reduced transport activity and expression of ABC transporters including ABCB1/Pgp and ABCC4/MRP4 in human colon adenocarcinoma Caco-2 cells. Carbon 41-47 ATP binding cassette subfamily C member 4 Homo sapiens 159-163 25150247-11 2014 AVAILABILITY AND IMPLEMENTATION: A free C++ implementation of cosi2 is available at http://broadinstitute.org/mpg/cosi2. Carbon 40-43 N-methylpurine DNA glycosylase Homo sapiens 110-113 25429945-0 2014 Reaction of the C3(X(1)Sigmag (+)) carbon cluster with H2S(X(1)A1), hydrogen sulfide: photon-induced formation of C3S, tricarbon sulfur. Carbon 35-41 complement C3 Homo sapiens 16-29 27896129-0 2014 One-carbon cycle alterations induced by Dyrk1a dosage. Carbon 4-10 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a Mus musculus 40-46 27896129-7 2014 The positive correlation found between liver Dyrk1a protein expression and CBS activity in modified and non-modified genetic context strengthens the role of this kinase in one carbon metabolism. Carbon 176-182 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a Mus musculus 45-51 25412303-2 2014 The enzyme serine hydroxymethyltransferase (SHMT) has a key role in this metabolic shift, and directs serine carbons to one-carbon units metabolism and thymidilate synthesis. Carbon 109-116 serine hydroxymethyltransferase 2 Homo sapiens 44-48 25412303-2 2014 The enzyme serine hydroxymethyltransferase (SHMT) has a key role in this metabolic shift, and directs serine carbons to one-carbon units metabolism and thymidilate synthesis. Carbon 109-115 serine hydroxymethyltransferase 2 Homo sapiens 44-48 25284253-2 2014 We recently developed novel non-secosteroidal VDR agonists based on p-carborane (an icosahedral carbon-containing boron cluster) as a hydrophobic core structure. Carbon 96-102 vitamin D receptor Homo sapiens 46-49 25353381-6 2014 The character and origin of the carbon-centered spin-adducts was confirmed using nitroso spin trapping agents. Carbon 32-38 spindlin 1 Homo sapiens 48-52 25353381-6 2014 The character and origin of the carbon-centered spin-adducts was confirmed using nitroso spin trapping agents. Carbon 32-38 spindlin 1 Homo sapiens 89-93 24973565-3 2014 Strikingly, mutants deficient in Isc1p display several hallmarks of mitochondrial dysfunction such as the inability to grow on a non-fermentative carbon course, increased oxidative stress and aberrant mitochondrial morphology. Carbon 146-152 inositol phosphosphingolipid phospholipase Saccharomyces cerevisiae S288C 33-38 25100852-7 2014 The PCP domain was shown to have deubiquitinase activity for both RIG-I and TBK-1, whose ubiquitination is a key step in their activation in poly(I C)-induced IFN induction. Carbon 5-6 DExD/H-box helicase 58 Homo sapiens 66-71 24654572-6 2014 The increase in average branching ratios and alkyl nitrate yields with increasing carbon number to a plateau value of ~0.30 at about C13-C14 is consistent with predictions of a previously developed model, indicating that the model is valid for alkane carbon numbers >=C3. Carbon 82-88 homeobox C13 Homo sapiens 133-136 24654572-6 2014 The increase in average branching ratios and alkyl nitrate yields with increasing carbon number to a plateau value of ~0.30 at about C13-C14 is consistent with predictions of a previously developed model, indicating that the model is valid for alkane carbon numbers >=C3. Carbon 251-257 homeobox C13 Homo sapiens 133-136 25223226-4 2014 EWR images reveal that single carbon atoms and carbon-fluorine pairs in C2F chair alternate strictly over domain sizes of at least 150 nm(2) with electron diffraction indicating ordered domains >= 0.16 mum(2). Carbon 30-36 EMG1 N1-specific pseudouridine methyltransferase Homo sapiens 72-75 25157679-8 2014 Taken together, this study provides a detailed mechanism by which three-carbon bridge exocyclic guanine adducts can be processed by AlkB and suggests an important role for the AlkB family of dioxygenases in protecting against the deleterious biological consequences of acrolein and MDA. Carbon 72-78 alkB homolog 1, histone H2A dioxygenase Homo sapiens 132-136 25157679-8 2014 Taken together, this study provides a detailed mechanism by which three-carbon bridge exocyclic guanine adducts can be processed by AlkB and suggests an important role for the AlkB family of dioxygenases in protecting against the deleterious biological consequences of acrolein and MDA. Carbon 72-78 alkB homolog 1, histone H2A dioxygenase Homo sapiens 176-180 25042206-1 2014 A one-step and mass-production synthetic route for a flexible reduced tungsten oxide-carbon composite nanofiber (WO(x)-C-NF) film is demonstrated via an electrospinning technique. Carbon 85-91 NPHS1 adhesion molecule, nephrin Homo sapiens 119-123 25042206-4 2014 Compared with previously reported tungsten oxide electrodes, the WO(x)-C-NF film exhibits high reversible capacity (481 mA h g(-1)total electrode), stable cycle, and improved rate performance, without the use of additive carbon, a polymeric binder and a current collector. Carbon 221-227 NPHS1 adhesion molecule, nephrin Homo sapiens 71-75 25044145-1 2014 Electronic effects on the central carbon atom of carbone, generated by the replacement of the S(IV) ligand of carbodisulfane (CDS) with other chalcogen ligands (Ph2 E, E=S or Se), were investigated. Carbon 34-40 polyhomeotic homolog 2 Homo sapiens 161-164 25039054-2 2014 Our results revealed that the low-affinity HXT1 permease allowed the maximal consumption of sugars and ethanol production rates during xylose/glucose co-fermentations, but was incapable to allow xylose uptake when this sugar was the only carbon source. Carbon 238-244 hexose transporter HXT1 Saccharomyces cerevisiae S288C 43-47 24856106-5 2014 The cell-binding activity of bound tropoelastin was modulated by ion implantation of the underlying polymer, and correlated with surface hydrophobicity, carbon and oxygen content. Carbon 153-159 elastin Homo sapiens 35-47 24968260-8 2014 The spectra indicate a significant electron/spin density (rho ~ 0.1) on each meso-carbon atom. Carbon 82-88 spindlin 1 Homo sapiens 44-48 24924143-1 2014 External supply of sucrose to carbon-starved Arabidopsis seedlings induced changes in phosphorylation of Brassinosteroid Signaling Kinase 8 (BSK8) at two different sites. Carbon 30-36 kinase with tetratricopeptide repeat domain-containing protein Arabidopsis thaliana 105-139 24924143-1 2014 External supply of sucrose to carbon-starved Arabidopsis seedlings induced changes in phosphorylation of Brassinosteroid Signaling Kinase 8 (BSK8) at two different sites. Carbon 30-36 kinase with tetratricopeptide repeat domain-containing protein Arabidopsis thaliana 141-145 24909769-5 2014 GOx modified screen-printed carbon platinised electrodes (SPCPtEs) were developed for the selective determination of Cr(VI) using ferricyanide as redox mediator. Carbon 28-34 hydroxyacid oxidase 1 Homo sapiens 0-3 24885528-2 2014 The synthesis features a chiral pool approach to prepare the chiral C-9 unit containing a quaternary carbon center, an Ir-catalyzed C-H borylation to synthesize the 2-indoleboronic acid pinacol ester, and a Suzuki reaction to couple together the two key intermediates. Carbon 101-107 complement C9 Homo sapiens 68-71 24737463-2 2014 Spin-trapping experiments indicate both an aryl-type radical and an oxidising radical, trapped as a carbon-centred radical, are formed from the protonated radical anion of SN30000. Carbon 100-106 spindlin 1 Homo sapiens 0-4 24773071-2 2014 Tabercarpamines C-F (3-6) are rare C-14/C-15-seco-tabersonine-type monoterpenoid indole alkaloids, and 5 and 6 are the first examples with a lactone linkage between C-14 and C-20. Carbon 16-17 placenta associated 8 Homo sapiens 40-44 24665070-0 2014 Kilogram-scale production of SnO(2) yolk-shell powders by a spray-drying process using dextrin as carbon source and drying additive. Carbon 98-104 strawberry notch homolog 2 Homo sapiens 29-32 24464681-0 2014 Influence of carbon and metal oxide nanomaterials on aqueous concentrations of the munition constituents cyclotrimethylenetrinitramine (RDX) and tungsten. Carbon 13-19 radixin Homo sapiens 136-139 24585881-8 2014 Our results indicate that the boost serves both to avert an autophagy program and to prolong the operation of key pathways that shuttle carbon from acetate into storage lipid, the combined outcome being enhanced TAG accumulation, notably in the sta6 strain. Carbon 136-142 uncharacterized protein Chlamydomonas reinhardtii 245-249 24651649-2 2014 We use the model to evaluate the properties of carbon near and on the Sigma5 (3 1 0)[0 0 1] symmetric tilt grain boundary (GB) in iron, and calculations show that a carbon atom lowers the GB energy by 0.29 eV/atom in accordance with DFT. Carbon 165-171 adaptor related protein complex 5 subunit sigma 1 Homo sapiens 70-76 24627965-6 2014 The natural anchoring group desosamine affords a 1:1 mixture of regioisomers, while synthetic anchors shift YC-17 analogue C-10/C-12 hydroxylation from 20:1 to 1:4. Carbon 109-110 chromosome 12 open reading frame 57 Homo sapiens 123-127 24371272-0 2014 Carbon source-dependent alteration of Puf3p activity mediates rapid changes in the stabilities of mRNAs involved in mitochondrial function. Carbon 0-6 mRNA-binding protein PUF3 Saccharomyces cerevisiae S288C 38-43 24371272-7 2014 However, Puf3p-mediated decay activity is inhibited in carbon sources that require mitochondrial function for efficient cell growth. Carbon 55-61 mRNA-binding protein PUF3 Saccharomyces cerevisiae S288C 9-14 24371272-8 2014 In addition, the activity of Puf3p is rapidly altered by changing the carbon source. Carbon 70-76 mRNA-binding protein PUF3 Saccharomyces cerevisiae S288C 29-34 24371272-11 2014 Together, these experiments provide insight into the carbon source-specific control of Puf3p activity and how such alterations allow Puf3p to dynamically regulate mitochondrial function. Carbon 53-59 mRNA-binding protein PUF3 Saccharomyces cerevisiae S288C 87-92 24588116-3 2014 Mechanism analysis suggests that this reversible phase transfer between water and [Emim]NTf2 is due to the relative affinity of the two solvents for the poly(ethylene oxide) units grafted on the carbon nanotubes. Carbon 195-201 nuclear transport factor 2 Homo sapiens 88-92 24402565-6 2014 In contrast, the NiO doping and the carbon layer covering the NiO-NiF2-C possibly facilitate the conversion process on the surface preserving the reaction kinetics upon the 2nd discharge. Carbon 36-42 zinc finger protein 335 Homo sapiens 66-70 24550542-4 2014 Depletion of p66Shc enhanced glycolysis and increased the allocation of glucose-derived carbon into anabolic metabolism, characteristics of a metabolic shift called the Warburg effect. Carbon 88-94 src homology 2 domain-containing transforming protein C1 Mus musculus 13-19 24333266-0 2014 Epigenetic modulation of RFC1, MHC2TA and HLA-DR in systemic lupus erythematosus: association with serological markers and six functional polymorphisms of one-carbon metabolic pathway. Carbon 159-165 replication factor C subunit 1 Homo sapiens 25-29 24333266-1 2014 The current study was conducted to elucidate the effect of genetic variations in one-carbon metabolism on the epigenetic regulation of major histocompatibility complex II transactivator (MHC2TA), reduced folate carrier 1 (RFC1/SLC19A1) and human leukocyte antigen (HLA)-DR in systemic lupus erythematosus (SLE). Carbon 85-91 replication factor C subunit 1 Homo sapiens 222-226 24333266-12 2014 To conclude, one-carbon genetic variants influence epigenetic of MHC2TA and RFC1, thus contributing to phenotypic heterogeneity of SLE. Carbon 17-23 replication factor C subunit 1 Homo sapiens 76-80 24520064-1 2014 UNLABELLED: The cyclic AMP receptor protein (Crp) is a transcriptional regulator that controls the expression of numerous bacterial genes, usually in response to environmental conditions and particularly by sensing the availability of carbon. Carbon 235-241 catabolite gene activator protein Escherichia coli 45-48 24520064-12 2014 Our work provides a mechanism by which the plague pathogen links not just the sensing of glucose or other carbon sources but also other signals that influence Crp abundance via the expression of small RNAs to the induction of the Crp regulon. Carbon 106-112 catabolite gene activator protein Escherichia coli 159-162 24520064-12 2014 Our work provides a mechanism by which the plague pathogen links not just the sensing of glucose or other carbon sources but also other signals that influence Crp abundance via the expression of small RNAs to the induction of the Crp regulon. Carbon 106-112 catabolite gene activator protein Escherichia coli 230-233 26276616-0 2014 Charge Separation in P3HT:SWCNT Blends Studied by EPR: Spin Signature of the Photoinduced Charged State in SWCNT. Carbon 26-31 spindlin 1 Homo sapiens 55-59 24325301-1 2014 A hierarchical high-performance electrode with nanoacanthine-style polyaniline (PANI) deposited onto a carbon nanofiber/graphene oxide (CNF/GO) template was successfully prepared via an in situ polymerization process. Carbon 103-109 NPHS1 adhesion molecule, nephrin Homo sapiens 136-139 23944933-6 2014 Knockdown of IL-17 receptor (IL-17R) E, the specific receptor for IL-17C, using IL-17RE small interfering RNA, attenuated polyI:C-induced hBD2, CSF3, and S100A12 expression, without any reduction of polyI:C-induced IL-17C expression, which suggest that IL-17C enhances hBD2, CSF, and S100A12 expression in an autocrine/paracrine manner in NHBE cells. Carbon 128-129 interleukin 17 receptor E Homo sapiens 80-87 24983601-5 2014 The present results indicate that SnO2-based supports do not modify the oxygen reduction reaction mechanism on the Pt nanoparticle surface, but rather lead to catalysts with enhanced specific activity compared to Pt/carbon systems. Carbon 216-222 strawberry notch homolog 2 Homo sapiens 34-37 24268251-0 2014 Amperometric glucose biosensor based on glucose oxidase dispersed in multiwalled carbon nanotubes/graphene oxide hybrid biocomposite. Carbon 81-87 hydroxyacid oxidase 1 Homo sapiens 40-55 24268251-1 2014 An amperometric glucose biosensor based on enhanced and fast direct electron transfer (DET) of glucose oxidase (GOx) at enzyme dispersed multiwalled carbon nanotubes/graphene oxide (MWCNT/GO) hybrid biocomposite was developed. Carbon 149-155 hydroxyacid oxidase 1 Homo sapiens 95-110 24268251-1 2014 An amperometric glucose biosensor based on enhanced and fast direct electron transfer (DET) of glucose oxidase (GOx) at enzyme dispersed multiwalled carbon nanotubes/graphene oxide (MWCNT/GO) hybrid biocomposite was developed. Carbon 149-155 hydroxyacid oxidase 1 Homo sapiens 112-115 24256410-2 2013 Compound 8 with a 4-carbon bridge was the most active analogue and potently inhibited proliferation of folate receptor (FR) alpha-expressing Chinese hamster ovary and KB human tumor cells. Carbon 20-26 folate receptor alpha Cricetulus griseus 103-129 24168398-3 2013 The developed one-pot three-component consecutive reactions generate up to four contiguous stereocenters, including the C-3 all-carbon quaternary center, in a perfectly defined configuration. Carbon 128-134 complement C3 Homo sapiens 120-123 24100161-4 2013 Most of them were Adr1 targets, a key transcription factor required for growth in non-fermentable carbon sources. Carbon 98-104 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 18-22 24041549-1 2013 In this paper, a facile and efficient method is reported to prepare polyaniline/carbon nanofiber (PANI/CNF) hybrid films by in situ chemical polymerization of aniline. Carbon 80-86 NPHS1 adhesion molecule, nephrin Homo sapiens 103-106 24150725-1 2013 Methionine synthase (MTR) is required for the conversion of homocysteine (hcy) to methionine in the one-carbon metabolic pathway. Carbon 104-110 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 0-19 24057859-7 2013 In our present study, sheep PBMCs had significantly higher TLR3 mRNA levels, TLR3 specific ligand (Poly I:C) stimulation resulted in increased levels of IFN-gamma at transcriptional and translational levels along with IL-8 and IL-10 at transcriptional levels. Carbon 31-32 interleukin-8 Ovis aries 218-222 24148506-0 2013 Amperometric phenol biosensor based on covalent immobilization of tyrosinase on Au nanoparticle modified screen printed carbon electrodes. Carbon 120-126 tyrosinase Homo sapiens 66-76 24066352-1 2013 NIRF imaging of carbon nanodots derived from tire soot was clearly visualized in glioma in vitro and in vivo. Carbon 16-22 interleukin 17B Homo sapiens 0-4 23721177-5 2013 This study sought to assess the importance of SPLUNC1-mediated pulmonary responses in airway epithelial secretions, and to explore the biological relevance of SPLUNC1 to inhaled particles in a single-walled carbon nanotube (SWCNT) model. Carbon 207-213 BPI fold containing family A, member 1 Mus musculus 159-166 31986641-1 2013 Selective hydrogenation of phenol to cyclohexanone over a catalyst of polyaniline-functionalized carbon-nanofiber-supported palladium (Pd-PANI/CNF) with sodium formate as the hydrogen source has been studied. Carbon 97-103 NPHS1 adhesion molecule, nephrin Homo sapiens 143-146 24022382-5 2013 The carbon cavities of the fcc-C10 cubic carbon polymorph (with an effective size of ~3.5-4 A) are kinetically closed to common gaseous contaminants of He fluid (including: Ne, Ar, H2, and CO). Carbon 4-10 relaxin 2 Homo sapiens 181-191 24022382-5 2013 The carbon cavities of the fcc-C10 cubic carbon polymorph (with an effective size of ~3.5-4 A) are kinetically closed to common gaseous contaminants of He fluid (including: Ne, Ar, H2, and CO). Carbon 41-47 relaxin 2 Homo sapiens 181-191 24038811-2 2013 The alkyl and Sn moieties were introduced at the beta and alpha carbon atoms of alkynoates, respectively, in a formal syn addition mode with complete regioselectivity. Carbon 64-70 synemin Homo sapiens 118-121 24567903-7 2014 Metabolomic analysis of CG9510 knockdown flies confirmed functional similarity to ASL, regulating the balance of carbon and nitrogen metabolism. Carbon 113-119 argininosuccinate lyase Homo sapiens 82-85 24024628-1 2013 Carbon nanofiber/nanotube (CNF/CNT) composite catalysts grown on carbon felt (CF), prepared from a simple way involving the thermal decomposition of acetylene gas over Ni catalysts, are studied as electrode materials in a vanadium redox flow battery. Carbon 0-6 NPHS1 adhesion molecule, nephrin Homo sapiens 27-30 24088297-1 2013 BACKGROUND: Dietary supplementation with botanical oils that contain n-6 and n-3 eighteen carbon chain (18C)-PUFA such as gamma linolenic acid (GLA, 18:3n-6), stearidonic acid (SDA, 18:4n-3) and alpha linolenic acid (ALA, 18:3n-3) have been shown to impact PUFA metabolism, alter inflammatory processes including arachidonic acid (AA) metabolism and improve inflammatory disorders. Carbon 90-96 pumilio RNA binding family member 3 Homo sapiens 109-113 24088297-1 2013 BACKGROUND: Dietary supplementation with botanical oils that contain n-6 and n-3 eighteen carbon chain (18C)-PUFA such as gamma linolenic acid (GLA, 18:3n-6), stearidonic acid (SDA, 18:4n-3) and alpha linolenic acid (ALA, 18:3n-3) have been shown to impact PUFA metabolism, alter inflammatory processes including arachidonic acid (AA) metabolism and improve inflammatory disorders. Carbon 90-96 pumilio RNA binding family member 3 Homo sapiens 257-261 26992753-20 2013 A statistically significant correlation was found between C of CEAP and the VCSS (r = 0.778; P < .001). Carbon 58-59 biogenesis of lysosomal organelles complex 1 subunit 2 Homo sapiens 63-67 23904514-9 2013 Ovarian steroid-induced IL-15 expression on HUtMVECs was not attenuated by chondroitinase ABC (which degrades chondroitin sulfate-A and -C and dermatan sulfate) or sodium acetate buffer (which dissociates cytokines from their cognate receptors). Carbon 50-51 interleukin 15 Homo sapiens 24-29 24019487-1 2013 Sea ice can contain high concentrations of dissolved organic carbon (DOC), much of which is carbohydrate-rich extracellular polymeric substances (EPS) produced by microalgae and bacteria inhabiting the ice. Carbon 61-67 14-3-3epsilon Drosophila melanogaster 146-149 23897395-1 2013 Nitrogen enriched mesoporous carbon (N-MCS) with extremely high mesopore volume and nitrogen content is prepared through a one-step hard template method. Carbon 29-35 Miles-Carpenter X-linked mental retardation syndrome Homo sapiens 39-42 24058536-4 2013 The administration of poly(I:C) plus D-galactosamine (D-GalN) in mice led to acute liver injury associated with the induction of IL-33 expression in liver sinusoidal endothelial cells (LSEC) and vascular endothelial cells (VEC), while the administration of poly(I:C) alone led to hepatocyte specific IL-33 expression in addition to vascular IL-33 expression. Carbon 29-30 interleukin 33 Mus musculus 129-134 24058536-4 2013 The administration of poly(I:C) plus D-galactosamine (D-GalN) in mice led to acute liver injury associated with the induction of IL-33 expression in liver sinusoidal endothelial cells (LSEC) and vascular endothelial cells (VEC), while the administration of poly(I:C) alone led to hepatocyte specific IL-33 expression in addition to vascular IL-33 expression. Carbon 29-30 interleukin 33 Mus musculus 300-305 24058536-4 2013 The administration of poly(I:C) plus D-galactosamine (D-GalN) in mice led to acute liver injury associated with the induction of IL-33 expression in liver sinusoidal endothelial cells (LSEC) and vascular endothelial cells (VEC), while the administration of poly(I:C) alone led to hepatocyte specific IL-33 expression in addition to vascular IL-33 expression. Carbon 29-30 interleukin 33 Mus musculus 300-305 23850620-10 2013 In contrast, in response to poly(I:C), Cox2(-/-) mice exhibited enhanced plasma interferon (IFNalpha,beta,gamma,lambda) and related cytokine responses (IP-10, IL-12). Carbon 35-36 interferon beta 1, fibroblast Mus musculus 73-105 23657116-2 2013 Maf1-depleted cells manifest elevated tRNA transcription and inability to grow on non-fermentable carbon source, such as glycerol. Carbon 98-104 RNA polymerase III-inhibiting protein MAF1 Saccharomyces cerevisiae S288C 0-4 28811428-1 2013 Local synthesis and direct integration of carbon nanotubes (CNTs) into microsystems is a promising method for producing CNT-based devices in a single step, low-cost, and wafer-level, CMOS/MEMS-compatible process. Carbon 42-48 MOS proto-oncogene, serine/threonine kinase Homo sapiens 183-187 23792098-6 2013 Further studies revealed the cells lacking SDO1 were compromised in growth on non-fermentable carbon sources suggesting mitochondrial function was impaired. Carbon 94-100 guanine nucleotide exchange factor SDO1 Saccharomyces cerevisiae S288C 43-47 23624482-5 2013 pH and organic carbon content influenced the ratio of AOA/AOB OTU numbers significantly. Carbon 15-21 aprataxin Homo sapiens 54-65 23624482-7 2013 This result suggested that AOA may contribute more than AOB to the upstream reaches of the Qiantang River, where the pH is lower and the organic carbon and NH4(+)-N contents are higher, but AOB were the principal driver of nitrification downstream, where the opposite environmental conditions were present. Carbon 145-151 aprataxin Homo sapiens 27-30 23881414-9 2013 These results suggest that FPGS1-mediated folate polyglutamylation is required for DNA methylation and H3K9 dimethylation through its function in one-carbon metabolism. Carbon 150-156 DHFS-FPGS homolog B Arabidopsis thaliana 27-32 23376101-2 2013 The newly designed materials were used to develop a novel glucose biosensor by immobilizing glucose oxidase (GOx) onto the SiO2-PA nanocomposites film on the surface of glassy carbon electrode (GCE). Carbon 176-182 hydroxyacid oxidase 1 Homo sapiens 92-107 23376101-2 2013 The newly designed materials were used to develop a novel glucose biosensor by immobilizing glucose oxidase (GOx) onto the SiO2-PA nanocomposites film on the surface of glassy carbon electrode (GCE). Carbon 176-182 hydroxyacid oxidase 1 Homo sapiens 109-112 23497876-0 2013 Application of reduced graphene oxide and carbon nanotube modified electrodes for measuring the enzymatic activity of alcohol dehydrogenase. Carbon 42-48 aldo-keto reductase family 1 member A1 Homo sapiens 118-139 23523259-11 2013 Comparison of the structures of three borapetosides suggests clearly that the C-8 stereochemistry plays a key role in hypoglycemic effect since the active borapetoside A and C possess 8R-chirality but the inactive borapetoside B possess 8S-chirality. Carbon 0-1 cell division cycle associated 3 Mus musculus 78-81 23705927-12 2013 BarA might function as a sensor to assess the metabolic state of the cell, including carbon starvation, leading to expression of the mxd operon and therefore control biofilm formation. Carbon 85-91 two-component sensor histidine kinase BarA Shewanella oneidensis MR-1 0-4 23601276-4 2013 The novel glucose biosensor was fabricated by immobilizing the positively charged Au nanoparticles, H30-SO3H nanoparticles and glucose oxidase (GOx) onto the surface of glassy carbon electrode (GCE). Carbon 176-182 hydroxyacid oxidase 1 Homo sapiens 144-147 23611185-1 2013 An insoluble salt of the water oxidation catalyst [Co9(H2O)6(OH)3(HPO4)2(PW9O34)3](16-) (Co9) has been used to modify amorphous carbon paste electrodes. Carbon 128-134 phosphoserine phosphatase pseudogene 1 Homo sapiens 51-54 23611185-1 2013 An insoluble salt of the water oxidation catalyst [Co9(H2O)6(OH)3(HPO4)2(PW9O34)3](16-) (Co9) has been used to modify amorphous carbon paste electrodes. Carbon 128-134 phosphoserine phosphatase pseudogene 1 Homo sapiens 89-92 23599271-10 2013 Altogether, these results suggest that, beyond its role in pectin biosynthesis, GAUT4 interferes with carbon metabolism, partitioning, and allocation. Carbon 102-108 galacturonosyltransferase 4 Arabidopsis thaliana 80-85 23420195-1 2013 A dual signal amplification strategy was designed for electrochemical detection of matrix metalloproteinase-9 with the integration of electrically heated carbon electrode technique and quantum dots labels. Carbon 154-160 matrix metallopeptidase 9 Homo sapiens 83-109 23411433-2 2013 The studied transformation is based on the Mo(VI)-catalyzed isomerization of carbohydrate carbon skeleton and allows preparation of C-3 isomers of 3-C-branched aldoses in a simple way without formation of side products. Carbon 90-96 complement C3 Homo sapiens 132-135 23411433-3 2013 This rearrangement at C-3 carbon differs from the previously described epimerization at C-2 of aldoses catalyzed by Mo(VI) ions, known as Bilik reaction. Carbon 26-32 complement C3 Homo sapiens 22-25 23498687-2 2013 The detection platform was constructed by conjugation of anti-BRCA1 on glassy carbon electrodes which were modified by mesoporous carbon nanospheres-toluidine blue nanocomposite (MCN-TB)/room temperature ionic-liquid (RTIL) composited film. Carbon 78-84 BRCA1 DNA repair associated Homo sapiens 62-67 23357280-1 2013 We previously showed that knockdown of the anaplerotic enzyme pyruvate carboxylase in the INS-1 832/13 insulinoma cell line inhibited glucose-stimulated insulin release and glucose carbon incorporation into lipids. Carbon 181-187 pyruvate carboxylase Rattus norvegicus 62-82 23462715-3 2013 We found that replacement of the quaternary carbon in the bis-phenol skeleton with silicon increased AR-antagonistic activity and reduced VDR-agonistic activity, that is, the AR selectivity of the silicon-containing compounds was higher than that of corresponding carbon compounds. Carbon 44-50 vitamin D receptor Homo sapiens 138-141 23720887-7 2013 Protein profiling and isoenzymes analysis showed the expression of several heat-stable proteins and prominent isoenzymes of SOD in C-306, compared to PBW343. Carbon 131-132 SOD Triticum aestivum 124-127 23531539-2 2013 While respiratory carbon oxidation pathways, electron transport, and ATP turnover are tightly coupled processes, AOX provides a means to relax this coupling, thus providing a degree of metabolic homeostasis to carbon and energy metabolism. Carbon 210-216 acyl-CoA oxidase 1 Homo sapiens 113-116 23425306-3 2013 The abilities of (14)C-labeled human and mouse apoA-I variants to associate with human HDL and lipid emulsion particles were determined using ultracentrifugation to separate free and bound protein. Carbon 21-22 apolipoprotein A-I Mus musculus 47-53 22964382-0 2013 Direct electrochemistry of glucose oxidase at electrochemically reduced graphene oxide-multiwalled carbon nanotubes hybrid material modified electrode for glucose biosensor. Carbon 99-105 hydroxyacid oxidase 1 Homo sapiens 27-42 22964382-1 2013 Direct electrochemistry of glucose oxidase (GOx) at an electrochemically reduced graphene oxide-multiwalled carbon nanotubes hybrid (ERGO-MWCNT) modified glassy carbon electrode (GCE) has been reported. Carbon 108-114 hydroxyacid oxidase 1 Homo sapiens 27-42 22964382-1 2013 Direct electrochemistry of glucose oxidase (GOx) at an electrochemically reduced graphene oxide-multiwalled carbon nanotubes hybrid (ERGO-MWCNT) modified glassy carbon electrode (GCE) has been reported. Carbon 108-114 hydroxyacid oxidase 1 Homo sapiens 44-47 22964382-1 2013 Direct electrochemistry of glucose oxidase (GOx) at an electrochemically reduced graphene oxide-multiwalled carbon nanotubes hybrid (ERGO-MWCNT) modified glassy carbon electrode (GCE) has been reported. Carbon 161-167 hydroxyacid oxidase 1 Homo sapiens 27-42 22964382-1 2013 Direct electrochemistry of glucose oxidase (GOx) at an electrochemically reduced graphene oxide-multiwalled carbon nanotubes hybrid (ERGO-MWCNT) modified glassy carbon electrode (GCE) has been reported. Carbon 161-167 hydroxyacid oxidase 1 Homo sapiens 44-47 23377456-0 2013 Strong spin-phonon coupling between a single-molecule magnet and a carbon nanotube nanoelectromechanical system. Carbon 67-73 spindlin 1 Homo sapiens 7-11 23377456-7 2013 Here, we provide the first experimental evidence for a strong spin-phonon coupling between a single molecule spin and a carbon nanotube resonator, ultimately enabling coherent spin manipulation and quantum entanglement. Carbon 120-126 spindlin 1 Homo sapiens 62-66 23377456-7 2013 Here, we provide the first experimental evidence for a strong spin-phonon coupling between a single molecule spin and a carbon nanotube resonator, ultimately enabling coherent spin manipulation and quantum entanglement. Carbon 120-126 spindlin 1 Homo sapiens 109-113 23377456-7 2013 Here, we provide the first experimental evidence for a strong spin-phonon coupling between a single molecule spin and a carbon nanotube resonator, ultimately enabling coherent spin manipulation and quantum entanglement. Carbon 120-126 spindlin 1 Homo sapiens 109-113 23512856-4 2013 The primary enzymatic product of TPS08, rhizathalene A, which is produced from the substrate all-trans geranylgeranyl diphosphate, represents a so far unidentified class of tricyclic diterpene carbon skeletons with an unusual tricyclic spiro-hydrindane structure. Carbon 193-199 Terpenoid cyclases/Protein prenyltransferases superfamily protein Arabidopsis thaliana 33-38 23188258-6 2013 The ratios of the yield of isolated AP sites to that of SSB induced by carbon ion or X-ray irradiation were relatively constant at 0.45 +- 0.15 over the tested range of scavenger capacity, although the ratio of SSB to double-strand breaks (DSB) showed the characteristic dependence on both scavenging capacity and radiation quality. Carbon 71-77 single-stranded DNA-binding protein Escherichia coli 56-59 32260738-3 2013 More details of the preparation of polyurethane-Pluronic F127 (PU-F127) nanospheres and immobilizing glucose oxidase (GOx) on (PU-F127)-glass carbon electrode (GCE) were presented. Carbon 142-148 hydroxyacid oxidase 1 Homo sapiens 101-116 32260738-3 2013 More details of the preparation of polyurethane-Pluronic F127 (PU-F127) nanospheres and immobilizing glucose oxidase (GOx) on (PU-F127)-glass carbon electrode (GCE) were presented. Carbon 142-148 hydroxyacid oxidase 1 Homo sapiens 118-121 22967951-0 2013 Peptide methionine sulfoxide reductase A (MsrA): direct electrochemical oxidation on carbon electrodes. Carbon 85-91 methionine sulfoxide reductase A Homo sapiens 42-46 22967951-1 2013 The direct electrochemical behaviour of peptide methionine sulfoxide reductase A (MsrA) adsorbed on glassy carbon and boron doped diamond electrodes surface, was studied over a wide pH range by cyclic and differential pulse voltammetry. Carbon 107-113 methionine sulfoxide reductase A Homo sapiens 82-86 22967951-6 2013 MsrA adsorbs on the hydrophobic carbon electrode surface preferentially through the three hydrophobic domains, C1, C2 and C3, which contain the tyrosine, tryptophan and histidine residues, and tryptophan exists only in these regions, and undergo electrochemical oxidation. Carbon 32-38 methionine sulfoxide reductase A Homo sapiens 0-4 22906713-2 2013 By combining laccase with catalase enzymes electrophoretically deposited by means of AC electric fields on multiple walled carbon nanotubes modified platinum black and, then stabilized by an outer layer of polypyrrole in the construction of GC/MWCNTs/Ptb/LAc-CAt/PPy biocathode, we can take advantage of the H(2)O(2) present in the solution or body tissue to increase the level of the dissolved O(2). Carbon 123-129 polypyrimidine tract binding protein 1 Homo sapiens 251-254 23069851-3 2013 The TPS1 deletion mutant strain YSH290 of the brewer"s yeast transformed by the truncated gene SpTPS1Delta and its original full-length version restored growth on the medium with glucose as a sole carbon source and displayed growth curves with no significant difference, indicating their encoding proteins functioning as TPS enzyme. Carbon 197-203 alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1 Saccharomyces cerevisiae S288C 4-8 23152952-0 2013 A biosensor fabricated by incorporation of a redox mediator into a carbon nanotube/nafion composite for tyrosinase immobilization: detection of matairesinol, an endocrine disruptor. Carbon 67-73 tyrosinase Homo sapiens 104-114 22796779-1 2013 We describe a simple method for preparing the hybrid material of Pt nanoparticles (NPs) supported on carbon-coated SnO(2) nanospheres (Pt-SnO(2)@C). Carbon 101-107 strawberry notch homolog 2 Homo sapiens 115-118 22796779-1 2013 We describe a simple method for preparing the hybrid material of Pt nanoparticles (NPs) supported on carbon-coated SnO(2) nanospheres (Pt-SnO(2)@C). Carbon 101-107 strawberry notch homolog 2 Homo sapiens 138-141 22796779-3 2013 The presence of carbon-coated SnO(2) nanospheres (SnO(2)@C) remarkably improves the electrocatalytic activity of Pt NPs towards hydrogen peroxide (H(2)O(2)) oxidation. Carbon 16-22 strawberry notch homolog 2 Homo sapiens 30-33 22796779-3 2013 The presence of carbon-coated SnO(2) nanospheres (SnO(2)@C) remarkably improves the electrocatalytic activity of Pt NPs towards hydrogen peroxide (H(2)O(2)) oxidation. Carbon 16-22 strawberry notch homolog 2 Homo sapiens 50-53 22796779-4 2013 The Pt-SnO(2)@C nanocomposite modified glassy carbon (GC) electrode exhibited enhanced amperometric response to H(2)O(2), with detection limit of 0.1 muM and sensitivity of 241.1 muA mM(-1) cm(-2). Carbon 46-52 strawberry notch homolog 2 Homo sapiens 7-10 24348034-0 2013 Biosensor based on tyrosinase immobilized on a single-walled carbon nanotube-modified glassy carbon electrode for detection of epinephrine. Carbon 61-67 tyrosinase Homo sapiens 19-29 24348034-0 2013 Biosensor based on tyrosinase immobilized on a single-walled carbon nanotube-modified glassy carbon electrode for detection of epinephrine. Carbon 93-99 tyrosinase Homo sapiens 19-29 24348034-1 2013 A biosensor comprising tyrosinase immobilized on a single-walled carbon nanotube-modified glassy carbon electrode has been developed. Carbon 65-71 tyrosinase Homo sapiens 23-33 23335616-4 2013 Transient overexpression of HAN also represses the expression of HAN and three other GATA3 family genes, HANL2 (HAN-LIKE 2), GNC (GATA, NITRATE-INDUCIBLE, CARBON-METABOLISM-INVOLVED), and GNL (GNC-LIKE), forming a negative regulatory feedback loop. Carbon 155-161 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 85-89 23147572-3 2013 Besides catalyzing the production of methylglycine (sarcosine) in one carbon metabolism pathway, GNMT was found to be able to bind a number of polycyclic aromatic hydrocarbons and inhibit DNA adducts formation. Carbon 70-76 glycine N-methyltransferase Mus musculus 97-101 23659110-0 2013 [Interannual changes in PAR and soil moisture during the warm season may be more important for directing of annual carbon balance in tundra than temperature fluctuations]. Carbon 115-121 jumping translocation breakpoint Homo sapiens 24-27 23171171-5 2012 This reduces the carbon deposition rate, and consequently a more well-defined CNF 3D architecture can be fabricated. Carbon 17-23 NPHS1 adhesion molecule, nephrin Homo sapiens 78-81 26290968-4 2012 These molecules undergo a thermally induced, fully reversible, gradual spin crossover with a transition temperature of T1/2 = 235(6) K and a transition width of DeltaT80 = 115(8) K. Our results show that by using a carbon-based substrate the spin-crossover behavior can be preserved even for molecules that are in direct contact with a solid surface. Carbon 215-221 spindlin 1 Homo sapiens 71-75 26290968-4 2012 These molecules undergo a thermally induced, fully reversible, gradual spin crossover with a transition temperature of T1/2 = 235(6) K and a transition width of DeltaT80 = 115(8) K. Our results show that by using a carbon-based substrate the spin-crossover behavior can be preserved even for molecules that are in direct contact with a solid surface. Carbon 215-221 spindlin 1 Homo sapiens 242-246 22982477-8 2012 Moreover, by playing a major role in the control of the stromal redox poise, PTOX is also capable of modulating the balance between linear and cyclic electron flow around PSI during the deactivation phase of carbon assimilation that follows a light to dark transition. Carbon 208-214 plastid quinol oxidase Solanum lycopersicum 77-81 22961754-6 2012 According to the molecular descriptors selected as the most predictive for PPB, the lipophilicity of the drugs, the presence of aromatic rings, cyano groups, and H-bond donor-acceptor pairs increase the PPB, whereas the presence of tertiary carbon atoms, four-member rings, and iodine atoms decrease PPB. Carbon 241-247 histatin 1 Homo sapiens 75-78 23092968-1 2012 We demonstrate the fabrication of hybrid nanocomposite electrodes with a combination of SnO(2) nanoparticles (NPs) and conducting multiwalled carbon nanotube (MWCNT) anodes (SnO(2)@CNT) through the direct anchoring of SnO(2) NPs on the surface of electrophoretically pre-deposited MWCNT (EPD-CNT) networks via a metal-organic chemical vapor deposition process. Carbon 142-148 strawberry notch homolog 2 Homo sapiens 174-177 23200047-1 2012 Lipoxygenase enzymes initiate diverse signaling pathways by specifically directing oxygen to different carbons of arachidonate and other polyunsaturated acyl chains, but structural origins of this specificity have remained unclear. Carbon 103-110 linoleate 9S-lipoxygenase-4 Glycine max 0-12 22825317-2 2012 Sarcosine is a key intermediate in 1-carbon metabolism and under normal circumstances is converted to glycine by the enzyme sarcosine dehydrogenase. Carbon 37-43 sarcosine dehydrogenase Homo sapiens 124-147 22818986-0 2012 The attenuation of restenosis following arterial gene transfer using carbon nanotube coated stent incorporating TAT/DNA(Ang1+Vegf) nanoparticles. Carbon 69-75 vascular endothelial growth factor A Canis lupus familiaris 125-129 22914602-9 2012 RESULTS: Long-acting beta2 agonists significantly down-regulated the poly I:C-induced IP-10 protein and messenger RNA expression in BEAS-2B cells. Carbon 76-77 C-X-C motif chemokine ligand 10 Homo sapiens 86-91 22914602-13 2012 CONCLUSION: Long-acting beta2 agonists down-regulate poly I:C-induced IP-10 expression in BEAS-2B cells via the beta2 adrenoreceptor-cyclic adenosine monophosphate and c-Jun N-terminal kinase/c-Jun pathways. Carbon 0-1 C-X-C motif chemokine ligand 10 Homo sapiens 70-75 22975243-1 2012 The NMR hyperpolarization observed for freely rotating methyl groups by exerting a temperature jump from 4.2 K to 298 K can be transferred to spins which have a spin, spin coupling with the carbon of the methyl group. Carbon 190-196 spindlin 1 Homo sapiens 142-146 22975243-1 2012 The NMR hyperpolarization observed for freely rotating methyl groups by exerting a temperature jump from 4.2 K to 298 K can be transferred to spins which have a spin, spin coupling with the carbon of the methyl group. Carbon 190-196 spindlin 1 Homo sapiens 161-165 22763782-1 2012 A rapid and simple procedure was developed for the preparation of a highly stable and leach-proof glucose oxidase (GOx)-bound glassy carbon electrode (GCE). Carbon 133-139 hydroxyacid oxidase 1 Homo sapiens 98-113 22763782-1 2012 A rapid and simple procedure was developed for the preparation of a highly stable and leach-proof glucose oxidase (GOx)-bound glassy carbon electrode (GCE). Carbon 133-139 hydroxyacid oxidase 1 Homo sapiens 115-118 22905002-1 2012 In the title compound, C(12)H(9)ClN(2)O(4)S, the N-H bond in the -SO(2)-NH- segment is syn to both the ortho-nitro group in the sulfonyl-benzene ring and the ortho-Cl atom in the aniline ring. Carbon 23-24 synemin Homo sapiens 87-90 22535206-6 2012 Cancer cells, as opposed to near-normal MCF-10A cells, exhibited significantly increased expression of key energy metabolic pathway enzymes (FBP1, IDH2, and G6PD) that are known to redirect cellular metabolism and increase carbon flux through the pentose phosphate pathway. Carbon 223-229 fructose-bisphosphatase 1 Homo sapiens 141-145 22535206-6 2012 Cancer cells, as opposed to near-normal MCF-10A cells, exhibited significantly increased expression of key energy metabolic pathway enzymes (FBP1, IDH2, and G6PD) that are known to redirect cellular metabolism and increase carbon flux through the pentose phosphate pathway. Carbon 223-229 glucose-6-phosphate dehydrogenase Homo sapiens 157-161 22335781-7 2012 TFT6 acts mainly in leaves and is involved in the systemic response to LP by regulating leaf carbon allocation and increasing phloem sucrose transport to promote root growth, while TFT7 directly functions in root by activating root plasma membrane H+-ATPase to release more protons under LP. Carbon 93-99 14-3-3 protein 6 Solanum lycopersicum 0-4 22836492-5 2012 TFT6 which acts mainly in leaves is involved in the systemic response to phosphorus deficiency by regulating leaf carbon allocation and increasing phloem sucrose transport to promote root growth, while TFT7 directly functions in root by activating root plasma membrane H (+) -ATPase to release more protons under phosphorus deficiency. Carbon 114-120 14-3-3 protein 6 Solanum lycopersicum 0-4 22373582-11 2012 In conclusion, our study supports the hypothesis that polymorphisms in one-carbon gene metabolisms modulate the risk for breast cancer, particularly the A1298C polymorphism of the MTHFR gene. Carbon 75-81 methylenetetrahydrofolate reductase Homo sapiens 180-185 22676413-0 2012 Cytochrome P450-catalyzed degradation of nicotine: fundamental parameters determining hydroxylation by cytochrome P450 2A6 at the 5"-carbon or the n-methyl carbon. Carbon 133-139 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 103-122 22635115-3 2012 The cuticular phenotypes of cer9 are associated with delayed onset of wilting in plants experiencing water deficit, lower transpiration rates, and improved water use efficiency measured as carbon isotope discrimination. Carbon 189-195 RING/U-box superfamily protein Arabidopsis thaliana 28-32 22946297-1 2012 The work is dedicated to creation of the mathematical model of folate-dependent one-carbon unit metabolism (FOCM) and study of its function in human placenta under homocysteine load and the most common mutations in the genes of methylenetetrahydrofolate reductase (MTHFR) and cystathionine beta-synthase (CBS). Carbon 84-90 methylenetetrahydrofolate reductase Homo sapiens 228-263 22628564-3 2012 Structural and biochemical studies show a direct, specific influence on the c-subunit stoichiometry, revealing c(<11), c(12), c(13), c(14), and c(>14) rings. Carbon 18-19 homeobox C13 Homo sapiens 129-134 22525679-10 2012 In a fermentable carbon source such as glucose, the negative GATA factor Dal80 binds to UGA4 promoter; only after the addition of the inducer, the positive factors Uga3, Dal81 and Gln3 interact with the promoter removing Dal80 and leading to gene induction. Carbon 17-23 Dal80p Saccharomyces cerevisiae S288C 73-78 22525679-10 2012 In a fermentable carbon source such as glucose, the negative GATA factor Dal80 binds to UGA4 promoter; only after the addition of the inducer, the positive factors Uga3, Dal81 and Gln3 interact with the promoter removing Dal80 and leading to gene induction. Carbon 17-23 Dal80p Saccharomyces cerevisiae S288C 221-226 22590291-1 2012 In the title compound, C(14)H(12)ClNO(3)S, the C=O bond is syn to the Cl substituent in the adjacent benzene ring. Carbon 23-24 synemin Homo sapiens 59-62 22306658-2 2012 In Saccharomyces cerevisiae, changes in carbon source lead to gene induction by Adr1 and Cat8 that are known to require the upstream function of the Snf1 protein kinase, the central regulator of carbon metabolism, to exert their activating effect. Carbon 40-46 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 80-84 22306658-2 2012 In Saccharomyces cerevisiae, changes in carbon source lead to gene induction by Adr1 and Cat8 that are known to require the upstream function of the Snf1 protein kinase, the central regulator of carbon metabolism, to exert their activating effect. Carbon 195-201 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 80-84 22434609-0 2012 Borylene complexes (BH)L2 and nitrogen cation complexes (N+)L2: isoelectronic homologues of carbones CL2. Carbon 92-100 endogenous retrovirus group W member 5 Homo sapiens 101-104 22245998-0 2012 Activation of HGF/c-Met signaling by ultrafine carbon particles and its contribution to alveolar type II cell proliferation. Carbon 47-53 hepatocyte growth factor Rattus norvegicus 14-17 22245998-2 2012 The present study aimed to explore the role of HGF and c-Met receptor in ultrafine carbon particle-induced alveolar type II epithelial (type II) cell proliferation. Carbon 83-89 hepatocyte growth factor Rattus norvegicus 47-50 20967558-10 2012 The latter are dephosphorylated by "low-molecular-weight protein-tyrosine-phosphatase-A" (LMW-PTP-A) before FN3KRP transfers a phosphate on the third carbon. Carbon 150-156 fructosamine 3 kinase related protein Homo sapiens 108-114 22363024-0 2012 Biogenic carbon-enriched and pollutant depleted SRF from commercial and pretreated heterogeneous waste generated by NIR sensor-based sorting. Carbon 9-15 serum response factor Homo sapiens 48-51 22461784-1 2012 ATIC, SHMT2, and SLC46A1 have essential roles in one-carbon (1-C) transfer. Carbon 53-59 serine hydroxymethyltransferase 2 Homo sapiens 6-11 22423853-6 2012 This leads to reduced electron spin-spin interaction and hence almost negligible intrinsic magnetism in the carbon-based PAHs and carbon nanographene fragments. Carbon 108-114 spindlin 1 Homo sapiens 31-35 22423853-6 2012 This leads to reduced electron spin-spin interaction and hence almost negligible intrinsic magnetism in the carbon-based PAHs and carbon nanographene fragments. Carbon 108-114 spindlin 1 Homo sapiens 36-40 22412605-1 2012 In the structure of the title compound, C(14)H(12)ClNO, the ortho-Cl atom in the benzoyl ring is positioned syn to the C=O bond, while the meta-methyl group in the aniline ring is positioned anti to the N-H bond. Carbon 40-41 synemin Homo sapiens 108-111 22237295-8 2012 Particle number, black carbon, NO(2), CO, PM(2.5), and sulfates were associated with ICAM-1 and VCAM-1. Carbon 23-29 intercellular adhesion molecule 1 Homo sapiens 85-91 22264584-2 2012 The three-dimensional (3D) TiO2-carbon composite exhibits a significant enhancement in the reaction rate in the decontamination of methylene blue, compared to the bare P25. Carbon 32-38 tubulin polymerization promoting protein Homo sapiens 168-171 22209074-1 2012 A novel electrochemical strategy for monitoring the activity and inhibition of T4 polynucleotide kinase (PNK) is developed by use of titanium ion (Ti(4+)) mediated signal transition coupled with signal amplification of single wall carbon nanotubes (SWCNTs). Carbon 231-237 polynucleotide kinase 3'-phosphatase Homo sapiens 105-108 22285943-3 2012 Here, we synthesized two series of novel non-secosteroidal VDR ligands with different spherical hydrophobic cores, that is, bicyclo[2.2.2]octane derivatives and p-carborane derivatives, and compared their biological activities in order to examine the difference between the interactions of the C-H hydrocarbon surface and the B-H carborane surface with the receptor. Carbon 294-295 vitamin D receptor Homo sapiens 59-62 22209804-0 2012 Macrophage receptor with collagenous structure (MARCO) is a dynamic adhesive molecule that enhances uptake of carbon nanotubes by CHO-K1 cells. Carbon 110-116 macrophage receptor MARCO Cricetulus griseus 0-46 22209804-0 2012 Macrophage receptor with collagenous structure (MARCO) is a dynamic adhesive molecule that enhances uptake of carbon nanotubes by CHO-K1 cells. Carbon 110-116 macrophage receptor MARCO Cricetulus griseus 48-53 22154704-4 2012 We report that impaired neurogenesis, disturbed micro-vascularization and loss of parvalbumin-expressing hippocampal interneurons, are found in the offspring of poly I:C-treated dams. Carbon 168-169 parvalbumin Rattus norvegicus 82-93 22082800-1 2012 Pt/carbon nanofiber (Pt/CNF) nanocomposites were facilely synthesized by the reduction of hexachloroplatinic acid (H(2)PtCl(6)) using formic acid (HCOOH) in aqueous solution containing electrospun carbon nanofibers at room temperature. Carbon 3-9 NPHS1 adhesion molecule, nephrin Homo sapiens 24-27 22354788-7 2012 Through detailed comparisons between the basis set effects and the solvent effects on the results, the gas-phase GIAO/WC04/6-311+G(2d,p)//B3LYP/6-31+G(d,p) was found to be specifically suitable for the prediction of (13)C NMR chemical shifts of chlorides in both chlorinated and non-chlorinated carbons. Carbon 295-302 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 140-143 22159407-0 2012 Carbon nanodots as fluorescence probes for rapid, sensitive, and label-free detection of Hg2+ and biothiols in complex matrices. Carbon 0-6 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 89-92 22127410-5 2012 Furthermore, the embedded and de-aggregated SnO(2) nanoparticles in the carbon phase, which are less than 10 nm in size, provide large numbers of reaction sites for lithium ions and ensure complete alloying with them. Carbon 72-78 strawberry notch homolog 2 Homo sapiens 44-47 22113586-1 2012 An efficient synthetic method for stereoselective construction of asymmetric quaternary carbon stereocenters, bearing nitrogen in the form of Boc-protected allyl amines, has been developed. Carbon 88-94 BOC cell adhesion associated, oncogene regulated Homo sapiens 142-145 22259503-3 2012 Furthermore, the C=O and O-H bonds of the carboxyl group are in syn positions with respect to each other. Carbon 17-18 synemin Homo sapiens 64-67 22213322-2 2012 The vitamin D receptor (VDR) binding affinity was further evaluated and 2alpha-methyl substituted 14-epi-1alpha,25(OH)(2)previtamin D(3) had 17-fold more potent affinity than 14-epi-1alpha,25(OH)(2)previtamin D(3).In the comparison of these compounds, the effects of thermal equilibrium, with or without 19-carbon at the A-ring, and their CD-ring structures are discussed. Carbon 307-313 vitamin D receptor Homo sapiens 4-22 22213322-2 2012 The vitamin D receptor (VDR) binding affinity was further evaluated and 2alpha-methyl substituted 14-epi-1alpha,25(OH)(2)previtamin D(3) had 17-fold more potent affinity than 14-epi-1alpha,25(OH)(2)previtamin D(3).In the comparison of these compounds, the effects of thermal equilibrium, with or without 19-carbon at the A-ring, and their CD-ring structures are discussed. Carbon 307-313 vitamin D receptor Homo sapiens 24-27 22113110-4 2012 These data revealed a structure-activity relationship which is that the large substituent group on beta-carbon resulted in low binding affinity of the phonphonate analog to VanX. Carbon 104-110 VanX protein Enterococcus faecium 173-177 22904629-0 2012 Single-walled carbon nanotubes promote rat vascular adventitial fibroblasts to transform into myofibroblasts by SM22-alpha expression. Carbon 14-20 transgelin Rattus norvegicus 112-122 22449827-10 2012 In addition, the expression levels of base excision enzymes that are involved in hOGG1, hMTH1, and MYH in MeT-5A cells remained unchanged for 24 h after carbon nanotube exposure. Carbon 153-159 mutY DNA glycosylase Homo sapiens 99-102 23284632-2 2012 In this study, the urea-induced unfolding process of the c-NADP-ME interface mutants was monitored using fluorescence and circular dichroism spectroscopy, analytical ultracentrifugation and enzyme activities. Carbon 28-29 malic enzyme 1 Homo sapiens 59-66 22679756-0 2012 [Structural and functional bases of the intermolecular interaction of calix[4]arene C-97 with myosin subfragment-1 of myometrium]. Carbon 84-85 myosin X Sus scrofa 94-100 22066785-1 2011 We report here the design and synthesis of a novel vitamin D receptor (VDR) agonist whose hydrophobic core structure is p-carborane (1,12-dicarba-closo-dodecaborane, an icosahedral carbon-containing boron cluster having remarkable thermal and chemical stability and a characteristically hydrophobic B-H surface). Carbon 181-187 vitamin D receptor Homo sapiens 51-69 22066785-1 2011 We report here the design and synthesis of a novel vitamin D receptor (VDR) agonist whose hydrophobic core structure is p-carborane (1,12-dicarba-closo-dodecaborane, an icosahedral carbon-containing boron cluster having remarkable thermal and chemical stability and a characteristically hydrophobic B-H surface). Carbon 181-187 vitamin D receptor Homo sapiens 71-74 22295759-1 2011 Crop residue, as an important element of agro-ecosystem, can influence the flow of nutrients, carbon, water, and energy in agro-ecosystem. Carbon 94-100 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 0-4 22295759-2 2011 As a crucial indicator of distribution of crop residue, crop residue fractional cover is a key parameter of agro-ecosystem carbon cycle process model. Carbon 123-129 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 42-46 22295759-2 2011 As a crucial indicator of distribution of crop residue, crop residue fractional cover is a key parameter of agro-ecosystem carbon cycle process model. Carbon 123-129 LUC7 like 3 pre-mRNA splicing factor Homo sapiens 56-60 22088060-1 2011 The role of spin-orbit and rotational couplings in radiative association of C((3)P) and N((4)S) atoms is investigated. Carbon 76-77 spindlin 1 Homo sapiens 12-16 22219998-1 2011 In the title compound, C(12)H(7)Cl(4)NO(2)S, the N-H bond in the C-SO(2)-NH-C segment is syn with respect to the ortho-Cl atom of the sulfonyl-benzene ring and one of the meta-Cl atoms of the aniline ring. Carbon 23-24 synemin Homo sapiens 89-92 21852690-5 2011 COX-1 and MnLOX abstracted hydrogen at C-11 of (12Z)-18:1 and C-12 of (13Z)-18:1. Carbon 0-1 RNA polymerase III subunit K Homo sapiens 39-43 21888426-3 2011 Spin-coated polymer films such as poly(methyl methacrylate), high-impact polystyrene or acrylonitrile-butadiene-styrene, or gas-phase methane were used as carbon sources. Carbon 155-161 spindlin 1 Homo sapiens 0-4 21795109-2 2011 The difference in the chemical shift of equatorial methylene proton and axial methylene proton at C(5) [Delta = delta(eq)-delta(ax)] is highly negative which is in contrast to the value observed in the corresponding parent piperidin-4-ones and this is attributed to the syn 1,3-diaxial interaction between the axial N-H bond and axial hydrogen at C-5. Carbon 98-99 synapsin I Homo sapiens 270-275 21839374-6 2011 Our results confirm the role of the lmo0501 gene in adaptation of L. monocytogenes cells to food preservation stress conditions as well as to the efficient utilization of glucose and fructose as carbon sources. Carbon 195-201 lmo0501 Listeria monocytogenes EGD-e 36-43 22003502-11 2011 The relative contribution of TAG compared to starch to the overall energy density increased 9.5-fold in one AGPRNAi-WRI1 transgenic line consistent with altered carbon partitioning from starch to oil. Carbon 161-167 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 116-120 22026679-1 2011 Experimental data from the Trident Laser facility is presented showing quasimonoenergetic carbon ions from nm-scaled foil targets with an energy spread of as low as +-15% at 35 MeV. Carbon 90-96 forkhead box M1 Homo sapiens 27-34 24062111-4 2011 In all of the investigated molecules the frontier orbital describing the corresponding p-electron density at the carbon atom to be protonated is HOMO as calculated by the HF/G3large//B3LYP/6-31G(d) level of theory. Carbon 113-119 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 185-188 21834035-4 2011 One case with OI IIC and the sibs had novel heterozygous mutations in the C-propeptide region of COL1A1, while the second patient with clear-cut OI IIC had no mutation in this region. Carbon 19-20 collagen type I alpha 1 chain Homo sapiens 97-103 21652782-3 2011 Mn(III) meso-tetrakis (N-hexylpyridinium-2-yl) porphyrin (MnTnHex-2-PyP) was synthesized to include four six-carbon (hexyl) side chains on the core MnPorphyrin structure. Carbon 109-115 pyrophosphatase (inorganic) 1 Mus musculus 68-71 21486309-2 2011 Plants using the C(4) pathway of carbon metabolism are marked by greater photosynthetic water and nitrogen-use efficiencies (PWUE and PNUE, respectively) than C(3) species, but it is unclear to what extent this is the case in C(3) -C(4) intermediate species. Carbon 33-39 complement C3 Homo sapiens 159-163 21486309-2 2011 Plants using the C(4) pathway of carbon metabolism are marked by greater photosynthetic water and nitrogen-use efficiencies (PWUE and PNUE, respectively) than C(3) species, but it is unclear to what extent this is the case in C(3) -C(4) intermediate species. Carbon 33-39 complement C3 Homo sapiens 226-230 21743899-2 2011 According to the calculations, the reaction proceeds via five steps: (1) oxidative addition of hydrosilane, (2) hydride migration to carbon-carbon double bond of tert-butyl acrylate, which determines the chirality at C2, (3) tautomerization from rhodium bound C-enolate to rhodium bound O-enolate, (4) intramolecular aldol reaction, which determines the chirality at C3 and consequently the anti/syn-selectivity, and (5) reductive elimination to release aldol product. Carbon 133-139 synemin Homo sapiens 396-399 21743899-2 2011 According to the calculations, the reaction proceeds via five steps: (1) oxidative addition of hydrosilane, (2) hydride migration to carbon-carbon double bond of tert-butyl acrylate, which determines the chirality at C2, (3) tautomerization from rhodium bound C-enolate to rhodium bound O-enolate, (4) intramolecular aldol reaction, which determines the chirality at C3 and consequently the anti/syn-selectivity, and (5) reductive elimination to release aldol product. Carbon 140-146 synemin Homo sapiens 396-399 21439380-7 2011 Primary reactions involve dehydroxylation at C-14 and side-chain cleavage between C-20 and C-22, thereby yielding 14-deoxy-20-hydroxyecdysone, poststerone and 14-deoxypoststerone. Carbon 45-46 Sp7 transcription factor 7 Mus musculus 91-95 21563315-1 2011 The hierarchically structured carbon nanofibers (CNFs)/carbon felt composites, in which CNFs were directly grown on the surface of microfibers in carbon felt, forming a CNF layer on a micrometer range that completely covers the microfiber surfaces, were tested as a novel support material for cobalt nanoparticles in the highly exothermic Fischer-Tropsch (F-T) synthesis. Carbon 30-36 NPHS1 adhesion molecule, nephrin Homo sapiens 49-52 21551149-8 2011 AVAILABILITY: The related C++ source code and datasets are available at http://ihome.cuhk.edu.hk/%7Eb118998/share/BASARD.zip. Carbon 26-29 death associated protein kinase 3 Homo sapiens 114-124 21507421-3 2011 Alternatively, the second adsorbent consisted of a multiscale web of ACF/CNF, which was prepared by growing carbon nanofibers (CNFs) on activated ACFs via catalytic chemical vapor deposition (CVD) and sonication, which was conducted to remove catalytic particles from the CNF tips and open the pores of the CNFs. Carbon 108-114 NPHS1 adhesion molecule, nephrin Homo sapiens 73-76 21721654-1 2011 The spin-dependent transport properties of single ferrocene, cobaltocene, and nickelocene molecules attached to the sidewall of a (4,4) armchair single-walled carbon nanotube via a Ni adatom are investigated by using a self-consistent ab initio approach that combines the non-equilibrium Green"s function formalism with the spin density functional theory. Carbon 159-165 spindlin 1 Homo sapiens 4-8 21421028-6 2011 Carbon black and small sized DEP generated from an Euro4 engine increased the surface expression of VCAM-1 and ICAM-1, whereas DEP from an engine representing an old combustion type engine (SRM2975) with larger particles did not affect the expression of cell adhesion molecules. Carbon 0-6 intercellular adhesion molecule 1 Homo sapiens 111-117 21539334-1 2011 This paper reports a novel self-templating methodology for the formation of SnO(2)-carbon hybrid hollow spheres by using Sn spheres as sacrificing templates. Carbon 83-89 strawberry notch homolog 2 Homo sapiens 76-79 21539334-3 2011 Moreover, the as-synthesized SnO(2)-carbon hybrid hollow spheres have been applied as anode materials for lithium-ion batteries, which exhibit a much higher initial Coulombic efficiency and better cycling performance than pure SnO(2) hollow spheres. Carbon 36-42 strawberry notch homolog 2 Homo sapiens 29-32 21539334-3 2011 Moreover, the as-synthesized SnO(2)-carbon hybrid hollow spheres have been applied as anode materials for lithium-ion batteries, which exhibit a much higher initial Coulombic efficiency and better cycling performance than pure SnO(2) hollow spheres. Carbon 36-42 strawberry notch homolog 2 Homo sapiens 227-230 21479798-1 2011 In bacteria, anaplerotic carbon fixation necessary for growth on carbon sources that are metabolized to three-carbon intermediates is provided by the activity of pyruvate carboxylase (PYC) and/or phosphoenolpyruvate carboxylase (PPC). Carbon 25-31 phosphoenolpyruvate carboxylase Bradyrhizobium diazoefficiens USDA 110 196-227 21479798-1 2011 In bacteria, anaplerotic carbon fixation necessary for growth on carbon sources that are metabolized to three-carbon intermediates is provided by the activity of pyruvate carboxylase (PYC) and/or phosphoenolpyruvate carboxylase (PPC). Carbon 65-71 phosphoenolpyruvate carboxylase Bradyrhizobium diazoefficiens USDA 110 196-227 21479798-1 2011 In bacteria, anaplerotic carbon fixation necessary for growth on carbon sources that are metabolized to three-carbon intermediates is provided by the activity of pyruvate carboxylase (PYC) and/or phosphoenolpyruvate carboxylase (PPC). Carbon 65-71 phosphoenolpyruvate carboxylase Bradyrhizobium diazoefficiens USDA 110 196-227 21314829-8 2011 The oxygen and carbon contents of wire VIM 2 did not exceed their maximum, of 0.070 and 0.050 wt%, according to ASTM standard (ASTM F-2063-00 2001). Carbon 15-21 vimentin 2, pseudogene Homo sapiens 39-44 21314829-12 2011 Overall, the number of cycles to failure was higher for VIM 2 wires with lower carbon content. Carbon 79-85 vimentin 2, pseudogene Homo sapiens 56-61 21491045-3 2011 In this manuscript we have tested this hypothesis by altering the central metal to Ta, Nb or V. Our calculations suggest that the tantalum analogue, TaL(3), will successfully bind to CO(2) in a mononuclear eta(2) arrangement and, importantly, will strongly activate one C-O bond to a point where spontaneous C-O cleavage occurs. Carbon 183-184 transaldolase 1 Homo sapiens 149-152 21539340-6 2011 Calculations of internal DMPC dynamics show that the relaxation times for carbon-hydrogen reorientation of choline decrease with an increase in cholesterol, but the main body (carbonyl-glycerol to C11) is independent of cholesterol concentration. Carbon 74-80 RNA polymerase III subunit K Homo sapiens 197-200 21734907-1 2011 Dissimilatory sulfate-reducing prokaryotes (SRB) are a very diverse group of anaerobic bacteria that are omnipresent in nature and play an imperative role in the global cycling of carbon and sulfur. Carbon 180-186 chaperonin containing TCP1 subunit 4 Homo sapiens 44-47 21754317-1 2011 In title compound, [Ca(C(7)H(5)O(2))(2)(C(7)H(6)O(2))(H(2)O)](n), the eightfold-coordinated Ca(II) ion is bonded to four carboxyl-ate O atoms from two benzoate ions, an O atom from benzoic acid and a water O atom. Carbon 20-21 carbonic anhydrase 2 Homo sapiens 92-98 21754375-2 2011 The benzene-connected portions of the alk-oxy substituents are almost coplanar with their respective rings [C-C-O-C torsion angles of 174.77 (17) and -178.5 (4) ]. Carbon 108-109 ALK receptor tyrosine kinase Homo sapiens 38-41 21754375-2 2011 The benzene-connected portions of the alk-oxy substituents are almost coplanar with their respective rings [C-C-O-C torsion angles of 174.77 (17) and -178.5 (4) ]. Carbon 110-111 ALK receptor tyrosine kinase Homo sapiens 38-41 21754375-2 2011 The benzene-connected portions of the alk-oxy substituents are almost coplanar with their respective rings [C-C-O-C torsion angles of 174.77 (17) and -178.5 (4) ]. Carbon 110-111 ALK receptor tyrosine kinase Homo sapiens 38-41 21300365-2 2011 The results revealed that the SnO(2) nanostructures were successfully grown on the primary electrospun carbon nanofibers substrates. Carbon 103-109 strawberry notch homolog 2 Homo sapiens 30-33 21417468-3 2011 The C-N bond-forming step proceeds via a syn-amidopalladation pathway. Carbon 4-5 synemin Homo sapiens 41-44 21391684-4 2011 In comparison to HP, the C-8 carbon chain analogue (HP-C8) showed significantly high, SR-assisted antiproliferative activity against cancer cells via caspase-3-mediated apoptosis and down-regulation of pAkt. Carbon 29-35 cell division cycle associated 3 Mus musculus 25-28 21391684-4 2011 In comparison to HP, the C-8 carbon chain analogue (HP-C8) showed significantly high, SR-assisted antiproliferative activity against cancer cells via caspase-3-mediated apoptosis and down-regulation of pAkt. Carbon 29-35 caspase 3 Mus musculus 150-159 21388211-2 2011 Depending on the position of the C-Zn bond relative to the nitrogen (position 2 vs position 4), the stereoselectivity of the coupling can be directed toward either the trans- or cis-2,4-disubstituted products. Carbon 33-34 suppressor of cytokine signaling 2 Homo sapiens 178-183 21687356-11 2011 In(13) C- NMR spectra, C-3 and C-5 of the 1,2,4 - triazole nucleus were observed in the range of delta 147-166.9 ppm. Carbon 7-8 complement C3 Homo sapiens 23-26 21323370-6 2011 CXCR1 undergoes rapid rotational diffusion about the normal of liquid crystalline phospholipid bilayers; reductions in the frequency span and a change to axial symmetry are observed for both carbonyl carbon and amide nitrogen chemical shift powder patterns of unoriented samples containing (13)C- and (15)N-labeled CXCR1. Carbon 191-197 C-X-C motif chemokine receptor 1 Homo sapiens 0-5 21323370-6 2011 CXCR1 undergoes rapid rotational diffusion about the normal of liquid crystalline phospholipid bilayers; reductions in the frequency span and a change to axial symmetry are observed for both carbonyl carbon and amide nitrogen chemical shift powder patterns of unoriented samples containing (13)C- and (15)N-labeled CXCR1. Carbon 0-1 C-X-C motif chemokine receptor 1 Homo sapiens 315-320 21429222-6 2011 RESULTS: At baseline, higher plasma MMP-9 levels were cross-sectionally associated with lower FEV1 (p=0.03), FVC (p<0.001), carbon monoxide transfer factor (p=0.03), resting oxygen saturation (p=0.02), and ISWT distance walked (p=0.02) but were not associated with radiographic lung density or total lung capacity (TLC). Carbon 127-133 matrix metallopeptidase 9 Homo sapiens 36-41 21309530-0 2011 Lewis acid catalyzed carbon-carbon bond cleavage of aryl oxiranyl diketones: synthesis of cis-2,5-disubstituted 1,3-dioxolanes. Carbon 21-27 suppressor of cytokine signaling 2 Homo sapiens 90-95 21309530-0 2011 Lewis acid catalyzed carbon-carbon bond cleavage of aryl oxiranyl diketones: synthesis of cis-2,5-disubstituted 1,3-dioxolanes. Carbon 28-34 suppressor of cytokine signaling 2 Homo sapiens 90-95 21204932-5 2011 The significance of the alkB-rub gene in n-alkane degradation was investigated in phenotypic tests, and the disruption mutant strain exhibited severely impaired growth on n-C(20) alkane carbon source. Carbon 186-192 alkB homolog 1, histone H2A dioxygenase Homo sapiens 24-28 21211901-7 2011 The activation energy for total carbon decomposition with HK and P25 are 29.5+-1.0 and 24.3+-3.1 kJ/mol, respectively. Carbon 32-38 tubulin polymerization promoting protein Homo sapiens 65-68 21522354-1 2011 In the title compound, C(10)H(12)ClNO(3)S, the amide H atom is syn with respect to the ortho-chloro group in the benzene ring and the C-S-N-C torsion angle is 64.35 (16) . Carbon 23-24 synemin Homo sapiens 63-66 21522354-1 2011 In the title compound, C(10)H(12)ClNO(3)S, the amide H atom is syn with respect to the ortho-chloro group in the benzene ring and the C-S-N-C torsion angle is 64.35 (16) . Carbon 33-34 synemin Homo sapiens 63-66 20843633-7 2011 Increasing carbon chain length of straight chain alcohols positively correlated with their ability to inhibit detection of tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10), but not with the detection of interleukin 6 (IL-6), interleukin 8, (IL-8), and interleukin 12 (IL-12). Carbon 11-17 interleukin 10 Homo sapiens 167-181 20843633-7 2011 Increasing carbon chain length of straight chain alcohols positively correlated with their ability to inhibit detection of tumor necrosis factor alpha (TNF-alpha) and interleukin 10 (IL-10), but not with the detection of interleukin 6 (IL-6), interleukin 8, (IL-8), and interleukin 12 (IL-12). Carbon 11-17 interleukin 10 Homo sapiens 183-188 20638345-0 2011 Amperometric glucose sensor based on glucose oxidase immobilized on gelatin-multiwalled carbon nanotube modified glassy carbon electrode. Carbon 88-94 hydroxyacid oxidase 1 Homo sapiens 37-52 20638345-0 2011 Amperometric glucose sensor based on glucose oxidase immobilized on gelatin-multiwalled carbon nanotube modified glassy carbon electrode. Carbon 120-126 hydroxyacid oxidase 1 Homo sapiens 37-52 20638345-1 2011 We investigated the direct electrochemistry of glucose oxidase (GOx) at gelatin-multiwalled carbon nanotube (GCNT) modified glassy carbon electrode (GCE). Carbon 92-98 hydroxyacid oxidase 1 Homo sapiens 47-62 20638345-1 2011 We investigated the direct electrochemistry of glucose oxidase (GOx) at gelatin-multiwalled carbon nanotube (GCNT) modified glassy carbon electrode (GCE). Carbon 92-98 hydroxyacid oxidase 1 Homo sapiens 64-67 20620237-0 2011 Photothermolysis of glioblastoma stem-like cells targeted by carbon nanotubes conjugated with CD133 monoclonal antibody. Carbon 61-67 prominin 1 Mus musculus 94-99 21523184-1 2011 In the title compound, C(12)H(17)NO(3)S, the amide H atom is syn to the ortho-methyl group of the benzene ring and the C-S-N-C torsion angle is -65.39 (17) . Carbon 23-24 synemin Homo sapiens 61-64 21146394-0 2011 Direct electron transfer from glucose oxidase immobilized on polyphenanthroline-modified glassy carbon electrode. Carbon 96-102 hydroxyacid oxidase 1 Homo sapiens 30-45 21042905-0 2011 Acridine orange-induced signal enhancement effect of tyrosinase-immobilized carbon-felt-based flow biosensor for highly sensitive detection of monophenolic compounds. Carbon 76-82 tyrosinase Homo sapiens 53-63 21275261-2 2011 Interestingly, mouse cells lacking poly(ADP-ribose) polymerase-1 are much more sensitive to C-1305 than their normal counterparts. Carbon 92-93 poly (ADP-ribose) polymerase family, member 1 Mus musculus 35-64 22039442-2 2011 Variation in one-carbon metabolism genes, particularly MTHFR, has been associated with risk of a number of cancers in epidemiologic studies, but little is known regarding renal cancer. Carbon 17-23 methylenetetrahydrofolate reductase Homo sapiens 55-60 21931597-10 2011 Based on these studies we hypothesize that, in S. oneidensis MR-1, the global BarA/UvrY/Csr regulatory pathway is involved in central carbon metabolism processes. Carbon 134-140 two-component sensor histidine kinase BarA Shewanella oneidensis MR-1 78-82 21673794-0 2011 Novel roles of cAMP receptor protein (CRP) in regulation of transport and metabolism of carbon sources. Carbon 88-94 catabolite gene activator protein Escherichia coli 15-36 21673794-0 2011 Novel roles of cAMP receptor protein (CRP) in regulation of transport and metabolism of carbon sources. Carbon 88-94 catabolite gene activator protein Escherichia coli 38-41 21673794-1 2011 CRP (cAMP receptor protein), the global regulator of genes for carbon source utilization in the absence of glucose, is the best-studied prokaryotic transcription factor. Carbon 63-69 catabolite gene activator protein Escherichia coli 0-3 21673794-1 2011 CRP (cAMP receptor protein), the global regulator of genes for carbon source utilization in the absence of glucose, is the best-studied prokaryotic transcription factor. Carbon 63-69 catabolite gene activator protein Escherichia coli 5-26 21673794-6 2011 Based on the functions of novel target genes, we conclude that CRP plays a key regulatory role in the whole processes from the selective transport of carbon sources, the glycolysis-gluconeogenesis switching to the metabolisms downstream of glycolysis, including tricarboxylic acid (TCA) cycle, pyruvate dehydrogenase (PDH) pathway and aerobic respiration. Carbon 150-156 catabolite gene activator protein Escherichia coli 63-66 20934908-4 2011 Also gamma-gauche and delta-effects of the alkyl groups at C-3 on the carbons of the aryl group at C-2 have been studied. Carbon 70-77 complement C3 Homo sapiens 59-62 22097040-2 2011 The particle and nutrient parameters of the rainwater, including turbidity, suspended solids, total organic carbon, and total phosphate, were lower in Tank 2, which had a surface-to-volume ratio 7.5 times greater than that of Tank 1. Carbon 108-114 tankyrase 2 Homo sapiens 151-157 20856944-0 2010 Facile nucleophilic substitution at the C3a tertiary carbon of the 3a-bromohexahydropyrrolo[2,3-b]indole scaffold. Carbon 53-59 complement C3 Homo sapiens 40-43 21121367-0 2010 ICAM-1 and VCAM-1 expression in rat aortic endothelial cells after single-walled carbon nanotube exposure. Carbon 81-87 intercellular adhesion molecule 1 Rattus norvegicus 0-6 21589477-2 2010 The mol-ecule adopts a syn-anti configuration with respect to the positions of the carbonyl groups and terminal phenyl rings relative to the thione S atom across the C-N bond. Carbon 166-167 synemin Homo sapiens 23-26 20859573-1 2010 A simple approach based on electrochemical impedance spectroscopy of a DNA hybridization sensor for breast cancer is reported by immobilizing a BRCA1 related 19 mer oligonucleotides ssDNA sequence on a glassy carbon electrode modified with a poly 5-carboxyindole conducting polymer. Carbon 209-215 BRCA1 DNA repair associated Homo sapiens 144-149 21070409-2 2010 In Arabidopsis, allosteric sensing of cellular energy and carbon levels alters the ability of PII to interact with target enzymes such as N-acetyl-l-glutamate kinase and heteromeric acetyl-coenzyme A carboxylase, thereby modulating the biological activity of these plastidial ATP- and carbon-consuming enzymes. Carbon 58-64 nitrogen regulatory P-II-like protein Arabidopsis thaliana 94-97 21070409-2 2010 In Arabidopsis, allosteric sensing of cellular energy and carbon levels alters the ability of PII to interact with target enzymes such as N-acetyl-l-glutamate kinase and heteromeric acetyl-coenzyme A carboxylase, thereby modulating the biological activity of these plastidial ATP- and carbon-consuming enzymes. Carbon 285-291 nitrogen regulatory P-II-like protein Arabidopsis thaliana 94-97 20707387-6 2010 The computed relative energies of the stereoselectivity-determining C-C bond formation TSs in the nonchelated pathway, for both 1a and 1c, indicate a preference toward Evans syn aldol product. Carbon 68-69 synemin Homo sapiens 174-177 20707387-6 2010 The computed relative energies of the stereoselectivity-determining C-C bond formation TSs in the nonchelated pathway, for both 1a and 1c, indicate a preference toward Evans syn aldol product. Carbon 70-71 synemin Homo sapiens 174-177 20634147-7 2010 The pGL3 plasmid containing a luciferase gene was damaged with diol epoxides of benzo[a]pyrene (B[a]P-DE), dibenzo[a,l]pyrene (DB[a,l]P-DE), benzo[g]chrysene (B[g]Ch-DE), and benzo[c]phenanthrene (B[c]Ph-DE). Carbon 180-182 succinate dehydrogenase complex subunit C Homo sapiens 4-8 20698559-1 2010 Syntheses, optical, and electrochemical properties of novel C-9 fluorenyl substituted anthracenes linked by a tetrahedral sp(3)-hybridized carbon atom are reported for blue light emitting materials. Carbon 139-145 complement C9 Homo sapiens 60-63 20809958-5 2010 Under anaerobic conditions, the overexpression of the PGM2 gene increased the ethanol yield and the xylose consumption rate in medium containing xylose as the only carbon source. Carbon 164-170 phosphoglucomutase PGM2 Saccharomyces cerevisiae S288C 54-58 19760087-5 2010 The most abundant species on the backup quartz filters were OC2 (250 degrees C) and OC3 (450 degrees C), accounting for approximately 80% of measured organic carbon on the backup quartz filters. Carbon 158-164 one cut homeobox 2 Homo sapiens 60-63 20704242-0 2010 Black carbon-mediated destruction of nitroglycerin and RDX by hydrogen sulfide. Carbon 6-12 radixin Homo sapiens 55-58 20367113-0 2010 An amperomertic uric acid biosensor based on immobilization of uricase onto polyaniline-multiwalled carbon nanotube composite film. Carbon 100-106 urate oxidase (pseudogene) Homo sapiens 63-70 21588335-1 2010 In the title compound, C(8)H(10)NO(2) (+) NO(3) (-), the cation is essentially planar with C-O-C-C and C-O-C-O torsion angles of -178.1 (2) and 2.1 (4) , respectively. Carbon 23-24 DAN domain BMP antagonist family member 5 Homo sapiens 103-110 20545859-7 2010 We also showed that Gal83 is the most important isoform not only for the growth on non-fermentable carbon sources, but also for regulation of ergosterol biosynthetic genes, under glucose-limited condition. Carbon 99-105 Gal83p Saccharomyces cerevisiae S288C 20-25 20439709-6 2010 We applied genetic analyses and (13)C carbon tracing to confirm that PEPCK is essential for growth of Mtb on fatty acids and catalyzes carbon flow from tricarboxylic acid cycle-derived metabolites to gluconeogenic intermediates. Carbon 38-44 phosphoenolpyruvate carboxykinase 1, cytosolic Mus musculus 69-74 20439709-6 2010 We applied genetic analyses and (13)C carbon tracing to confirm that PEPCK is essential for growth of Mtb on fatty acids and catalyzes carbon flow from tricarboxylic acid cycle-derived metabolites to gluconeogenic intermediates. Carbon 135-141 phosphoenolpyruvate carboxykinase 1, cytosolic Mus musculus 69-74 20459188-0 2010 Erratum: "Spin filter effect of manganese phthalocyanine contacted with single-walled carbon nanotube electrodes" [J. Chem. Carbon 86-92 spindlin 1 Homo sapiens 10-14 20059739-7 2010 The significance of raised malate and pyruvate levels in activation of AOX protein/AOX pathway, which in turn play an important role in dissipating excess chloroplastic reducing equivalents and sustenance of photosynthetic carbon assimilation to balance the effects of HL stress on photosynthesis, was depicted as a model. Carbon 223-229 acyl-CoA oxidase 1 Homo sapiens 71-74 20059739-7 2010 The significance of raised malate and pyruvate levels in activation of AOX protein/AOX pathway, which in turn play an important role in dissipating excess chloroplastic reducing equivalents and sustenance of photosynthetic carbon assimilation to balance the effects of HL stress on photosynthesis, was depicted as a model. Carbon 223-229 acyl-CoA oxidase 1 Homo sapiens 83-86 20391564-0 2010 Correction: Macroscopic Single-Walled-Carbon-Nanotube Fiber Self-Assembled by Dip-Coating Method. Carbon 38-44 DIP Homo sapiens 78-81 21137059-6 2010 RESULTS: Compared with the wild-type mice, proteins involved in the anti-oxidation/detoxification response, glycolytic energy metabolism and one-carbon metabolism pathways were down-regulated significantly in Gnmt(-/-) mice. Carbon 145-151 glycine N-methyltransferase Mus musculus 209-213 20490325-10 2010 ER and Ki67 expressions were reduced and increased, respectively, with the expression patterns being shifted from Cyt --> C-N --> N. In conclusion, piwil2 is expressed in various stages of breast cancers and has the potential to be used a novel biomarker. Carbon 114-115 piwi like RNA-mediated gene silencing 2 Homo sapiens 154-160 20163156-2 2010 This approach is based on the electrocatalytic reduction of enzymatically generated H(2)O(2) at the biosensor of uricase-thionine-single-walled carbon nanotube/glassy carbon (UOx-Th-SWNTs/GC) with the use of Th-SWNTs nanostructure as a mediator and an enzyme immobilization matrix. Carbon 144-150 urate oxidase (pseudogene) Homo sapiens 175-178 20163156-2 2010 This approach is based on the electrocatalytic reduction of enzymatically generated H(2)O(2) at the biosensor of uricase-thionine-single-walled carbon nanotube/glassy carbon (UOx-Th-SWNTs/GC) with the use of Th-SWNTs nanostructure as a mediator and an enzyme immobilization matrix. Carbon 167-173 urate oxidase (pseudogene) Homo sapiens 175-178 20103117-0 2010 Amperometric biosensor based on tyrosinase immobilized onto multiwalled carbon nanotubes-cobalt phthalocyanine-silk fibroin film and its application to determine bisphenol A. Carbon 72-78 tyrosinase Homo sapiens 32-42 20103117-1 2010 An amperometric bisphenol A (BPA) biosensor was fabricated by immobilizing tyrosinase on multiwalled carbon nanotubes (MWNTs)-cobalt phthalocyanine (CoPc)-silk fibroin (SF) composite modified glassy carbon electrode (GCE). Carbon 101-107 tyrosinase Homo sapiens 75-85 20000481-2 2010 In the M = 2S + 1 = 13 (S is the total spin) ground state (GS) of Fe(6)-(C(6)H(6))(3) each benzene is bonded with one Fe atom, forming eta(6) coordinations with C-Fe contacts of 2.12-2.17 A; though the Fe(6) cluster structure is preserved, it presents more distortion than in bare Fe(6). Carbon 73-74 spindlin 1 Homo sapiens 39-43 19954533-0 2009 Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice. Carbon 154-160 vascular endothelial growth factor A Mus musculus 85-89 19780152-4 2009 These differences reflect the exchange of the carbon 4, 5, and 6 moiety of fructose-6-phosphate and glyceraldehyde-3-phosphate catalyzed by transaldolase. Carbon 46-52 transaldolase 1 Homo sapiens 140-153 19778056-6 2009 On the basis of the proposed mechanism, the glyoxal interaction with alanine through a decarboxylative aldol addition reaction can lead to the formation of 1,2-butanedione with the terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine, and the similar interaction of 1,2-butanedione with a second molecule of alanine can lead to the formation of 3,4-hexanedione with both terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine. Carbon 196-202 complement C3 Homo sapiens 235-238 19778056-6 2009 On the basis of the proposed mechanism, the glyoxal interaction with alanine through a decarboxylative aldol addition reaction can lead to the formation of 1,2-butanedione with the terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine, and the similar interaction of 1,2-butanedione with a second molecule of alanine can lead to the formation of 3,4-hexanedione with both terminal ethyl carbon atoms originating from C-2" and C-3" atoms of alanine. Carbon 196-202 complement C3 Homo sapiens 448-451 21578371-2 2009 Furthermore, the conformation of the C=O bond is syn to the meta-methyl group in the benzoyl ring. Carbon 37-38 synemin Homo sapiens 49-52 19683424-0 2009 A glucose biosensor based on direct electrochemistry of glucose oxidase immobilized on nitrogen-doped carbon nanotubes. Carbon 102-108 hydroxyacid oxidase 1 Homo sapiens 56-71 19746958-3 2009 ILs and GOx were assembled on the surface of an electrode via single-walled carbon nanotubes (SWNTs) and poly(sodium 4-styrenesulfonate) (PSS) utilizing the electrostatic interaction. Carbon 76-82 hydroxyacid oxidase 1 Homo sapiens 8-11 19788314-0 2009 Adsorption of glucose oxidase onto single-walled carbon nanotubes and its application in layer-by-layer biosensors. Carbon 49-55 hydroxyacid oxidase 1 Homo sapiens 14-29 19788314-1 2009 In this study, we describe the use of a sodium cholate suspension-dialysis method to adsorb the redox enzyme glucose oxidase (GOX) onto single-walled carbon nanotubes (SWNT). Carbon 150-156 hydroxyacid oxidase 1 Homo sapiens 109-124 19788314-1 2009 In this study, we describe the use of a sodium cholate suspension-dialysis method to adsorb the redox enzyme glucose oxidase (GOX) onto single-walled carbon nanotubes (SWNT). Carbon 150-156 hydroxyacid oxidase 1 Homo sapiens 126-129 19075030-3 2009 C1P with an acyl-chain of >or=6 carbons efficiently activated cPLA(2)alpha in vitro, whereas C(2)-C1P, was unable to do so. Carbon 35-42 phospholipase A2 group IVA Homo sapiens 65-77 19075030-9 2009 Here, we demonstrate that C1P requires >or=6 carbon acyl-chain to activate cPLA(2)alpha. Carbon 48-54 phospholipase A2 group IVA Homo sapiens 78-90 19736974-1 2009 To elucidate a mechanism of prothrombotic effects of carbon nanotubes (CNTs), we report here that multiwalled CNTs activate blood platelets by inducing extracellular Ca(2+) influx that could be inhibited by calcium channel blockers SKF 96365 and 2-APB. Carbon 53-59 arginyl aminopeptidase Homo sapiens 248-251 19842489-4 2009 Complexes of C(NH3)2, C(PH3)2, C[P(CH3)3]2, CF2, CCl2, and imidazol-2-ylidene with such proton donors as H2O, HCF3, HCN and HCCH have been analyzed by means of high-level quantum chemical methods. Carbon 0-1 ATPase H+ transporting accessory protein 1 Homo sapiens 44-47 19551174-3 2009 The catalytic asymmetric direct Mannich reaction has provided elegant and efficient solutions for the stereocontrolled assembly of both syn- and anti-alpha,beta-diamino acid derivatives, including those with a alpha-tetrasubstituted carbon stereocenter, with the aid of either organometallic or purely organic chiral catalysts (or the combination of both). Carbon 233-239 synemin Homo sapiens 136-139 19673244-4 2009 The mass ratio of particulate organic carbon to sulfate at the base of the ship stack was 0.23 +/- 0.03, and increased to 0.30 +/- 0.01 in the airborne exhaust plume, with the additional organic mass in the airborne plume being concentrated largely in particles below 100 nm in diameter. Carbon 38-44 inositol polyphosphate-5-phosphatase D Homo sapiens 75-79 19627833-20 2009 We propose a semi-empirical model for arterial elastin given by W = c(0)(I(1) - 3) + c(1)(I(4) - 1)2 + c(2)(I(6) - 1)2, where c(0), c(1) and c(3) are unknown coefficients. Carbon 24-25 elastin Homo sapiens 47-54 19437455-1 2009 In the acetylenic aldehyde oximes with substituents containing silicon and germanium, the (13)C NMR signal of the C-2 carbon of triple bond is shifted by 3.5 ppm to lower frequency and that of the C-3 carbon is moved by 7 ppm to higher frequency on going from E to Z isomer. Carbon 118-124 complement C3 Homo sapiens 197-200 19437455-1 2009 In the acetylenic aldehyde oximes with substituents containing silicon and germanium, the (13)C NMR signal of the C-2 carbon of triple bond is shifted by 3.5 ppm to lower frequency and that of the C-3 carbon is moved by 7 ppm to higher frequency on going from E to Z isomer. Carbon 201-207 complement C3 Homo sapiens 197-200 19437455-2 2009 A greater low-frequency effect of 5.5 ppm on the C-2 carbon signal and a greater high-frequency effect of 11 ppm on the C-3 carbon signal are observed in the analogous acetylenic ketone oximes. Carbon 124-130 complement C3 Homo sapiens 120-123 19791508-2 2009 By comparing the interactions of each analogue with beta-tubulin, the structure-activity relationships are summarized as follow: C-2 benzoyl and taxane ring systems are the essential groups for microtubule binding, the improvements of bioactivity and bioavailability are dependent on the substituents at positions C-1, C-4, C-7, C-9, C-10, and C-14, whereas the C-13 side chain mainly provides a specific binding. Carbon 129-130 complement C7 Homo sapiens 324-327 19791508-2 2009 By comparing the interactions of each analogue with beta-tubulin, the structure-activity relationships are summarized as follow: C-2 benzoyl and taxane ring systems are the essential groups for microtubule binding, the improvements of bioactivity and bioavailability are dependent on the substituents at positions C-1, C-4, C-7, C-9, C-10, and C-14, whereas the C-13 side chain mainly provides a specific binding. Carbon 129-130 complement C9 Homo sapiens 329-332 19791508-2 2009 By comparing the interactions of each analogue with beta-tubulin, the structure-activity relationships are summarized as follow: C-2 benzoyl and taxane ring systems are the essential groups for microtubule binding, the improvements of bioactivity and bioavailability are dependent on the substituents at positions C-1, C-4, C-7, C-9, C-10, and C-14, whereas the C-13 side chain mainly provides a specific binding. Carbon 129-130 homeobox C13 Homo sapiens 362-366 19518155-1 2009 The modified cinchona alkaloid-catalyzed direct Mannich-type reaction of N-unprotected 2-oxindoles with N-Ts-imine was developed to afford anti-3,3-disubstituted 2-oxindoles with vicinal chiral quaternary and tertiary carbon centers in yields up to 90% with excellent diastereoselectivities (anti/syn up to 95:5) and good enantioselectivies (up to 89% ee). Carbon 218-224 synemin Homo sapiens 297-300 21582849-3 2009 The amine addition is highly stereospecific yielding exclusively a single diastereomer with R-configuration at the newly formed C-11 chiral carbon. Carbon 140-146 RNA polymerase III subunit K Homo sapiens 128-132 19424415-0 2009 Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. Carbon 20-26 phosphatidylinositol kinase-related protein kinase TOR1 Saccharomyces cerevisiae S288C 0-4 19678540-4 2009 Three of them, 1, 2 and 6, showed obvious activity to inhibit the production of IL-18, especially the ester saponins with a sugar chain at C-28, 6. Carbon 139-140 interleukin 18 Homo sapiens 80-85 19322936-2 2009 In yeast (Saccharomyces cerevisiae), the regulation of three MAP kinase pathways responding to pheromones (Fus3 pathway), carbon/nitrogen starvation (Kss1 pathway), and high osmolarity/osmotic stress (Hog1 pathway) is the subject of intensive research. Carbon 122-128 mitogen-activated serine/threonine-protein kinase KSS1 Saccharomyces cerevisiae S288C 150-154 19199664-2 2009 Bromonium ion induced transannular oxonium ion formation-fragmentation gave the macrocyclic carbon skeleton of obtusallene VII with a bromine atom at C-13, in line with a previously published hypothesis. Carbon 92-98 homeobox C13 Homo sapiens 150-154 19240236-2 2009 We hypothesized that genetic variation of genes for methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR), two critical enzymes in the one-carbon metabolism, may alter DNA methylation levels and thus influence DNA methylation in breast cancer. Carbon 159-165 methylenetetrahydrofolate reductase Homo sapiens 52-87 19240236-2 2009 We hypothesized that genetic variation of genes for methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR), two critical enzymes in the one-carbon metabolism, may alter DNA methylation levels and thus influence DNA methylation in breast cancer. Carbon 159-165 methylenetetrahydrofolate reductase Homo sapiens 89-94 19240236-2 2009 We hypothesized that genetic variation of genes for methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR), two critical enzymes in the one-carbon metabolism, may alter DNA methylation levels and thus influence DNA methylation in breast cancer. Carbon 159-165 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 100-119 19151130-5 2009 Furthermore, a low carbon assimilation rate of ntrc leaves was associated with enhanced transpiration and photorespiration. Carbon 19-25 NADPH-dependent thioredoxin reductase C Arabidopsis thaliana 47-51 19402520-3 2009 The n-alkane homolog from C10 to C33 were detected with the major peak carbon numbers ranging from 23 to 25. Carbon 71-77 CD82 molecule Homo sapiens 33-36 18842465-0 2009 Direct electrochemistry of glucose oxidase immobilized on NdPO4 nanoparticles/chitosan composite film on glassy carbon electrodes and its biosensing application. Carbon 112-118 hydroxyacid oxidase 1 Homo sapiens 27-42 18842465-1 2009 The direct electrochemistry of glucose oxidase (GOx) immobilized on a composite matrix based on chitosan (CHIT) and NdPO(4) nanoparticles (NPs) underlying on glassy carbon electrode (GCE) was achieved. Carbon 165-171 hydroxyacid oxidase 1 Homo sapiens 31-46 18842465-1 2009 The direct electrochemistry of glucose oxidase (GOx) immobilized on a composite matrix based on chitosan (CHIT) and NdPO(4) nanoparticles (NPs) underlying on glassy carbon electrode (GCE) was achieved. Carbon 165-171 hydroxyacid oxidase 1 Homo sapiens 48-51 19060147-10 2009 The results suggest that the Fnr and Crp proteins may act synergistically to enhance NapABC synthesis during growth with poor carbon sources to help obtain energy from low levels of nitrate. Carbon 126-132 catabolite gene activator protein Escherichia coli 37-40 18467027-6 2009 The result indicated that all the above four ozonation processes result in significant decomposition of DMP and mineralization of total organic carbon (TOC) at the applied ozone dosage per volume of liquid sample of 1.2gL(-1). Carbon 144-150 rhomboid 5 homolog 2 Homo sapiens 152-155 18773201-7 2009 rEML1 preferentially hydrolyzed triacylglycerols acyl-group chains with long chain lengths of > or = 8 carbon atoms and displayed hydrolyzing activities toward various natural oil substrates. Carbon 106-112 EMAP like 1 Rattus norvegicus 0-5 19458444-1 2009 Arrays of Carbon nanofibers (CNFs) harness the advantages of individual CNF as well the collective property of assemblies, which made them promising materials in biosensing and tissue engineering or implantation. Carbon 10-16 NPHS1 adhesion molecule, nephrin Homo sapiens 29-32 19165387-6 2009 CONCLUSION: The compensatory nature of both effects (shielding of carbon core and biotransformation of PAHs) results in a good correlation between inflammatory response and BET surface area for all CDNPs. Carbon 66-72 delta/notch-like EGF repeat containing Mus musculus 173-176 19053775-6 2008 The X-ray crystal structure of the mofegiline-MAO-B adduct shows a covalent bond between the flavin cofactor N(5) with the distal allylamine carbon atom as well as the absence of the fluorine atom. Carbon 141-147 monoamine oxidase B Homo sapiens 46-51 19070577-7 2008 We speculate that AEP2 and OLI1 have evolved during the adaptation of S. bayanus to nonfermentable carbon sources, thereby driving speciation. Carbon 99-105 F0 ATP synthase subunit c Saccharomyces cerevisiae S288C 27-31 18820257-4 2008 The result showed that the C-terminal Asp residue of the heavy chains forms an ester bond to Ser(28) beta-carbon of TSG-6 suggesting that this residue plays a role during catalysis. Carbon 106-112 TNF alpha induced protein 6 Homo sapiens 116-121 18816068-0 2008 Electrochemical biosensor for detection of BCR/ABL fusion gene using locked nucleic acids on 4-aminobenzenesulfonic acid-modified glassy carbon electrode. Carbon 137-143 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 43-50 19083487-2 2008 This 5-carbon sugar, synthesized from glucose via the pentose phosphate pathway, has a rate-limiting step at glucose-6-phosphate dehydrogenase. Carbon 7-13 glucose-6-phosphate dehydrogenase Homo sapiens 109-142 18689527-7 2008 Strains lacking ACH1 have a mild growth defect on some carbon sources but are fully virulent in a mouse model of disseminated candidiasis. Carbon 55-61 acyl-CoA thioesterase 7 Mus musculus 16-20 21203298-2 2008 Furthermore, the conformation of the C=O group with respect to the methyl substituent in the 2-methyl-phenyl ring is syn, as has also been observed in related structures. Carbon 37-38 synemin Homo sapiens 117-120 18495203-4 2008 However, in tap water having a high concentration of organic carbon from acetate addition, orthophosphate addition promoted the growth of bacteria, allowed more bacteria to assemble on corroded and uncorroded surfaces, and increased the consumption of organic carbon. Carbon 61-67 nuclear RNA export factor 1 Homo sapiens 12-15 17980962-7 2008 CNT2 presents a higher adsorption capacity than CNT1 due to the existence of an exterior amorphous carbon layer on CNT2. Carbon 99-105 solute carrier family 28 member 2 Homo sapiens 0-4 17980962-7 2008 CNT2 presents a higher adsorption capacity than CNT1 due to the existence of an exterior amorphous carbon layer on CNT2. Carbon 99-105 solute carrier family 28 member 1 Homo sapiens 48-52 17980962-7 2008 CNT2 presents a higher adsorption capacity than CNT1 due to the existence of an exterior amorphous carbon layer on CNT2. Carbon 99-105 solute carrier family 28 member 2 Homo sapiens 115-119 21825789-1 2008 We report on the fabrication of a carbon nanotube field emission backlight unit (CNT-BLU) and its application for liquid crystal displays (LCD). Carbon 34-40 zinc finger MYND-type containing 10 Homo sapiens 85-88 18560472-2 2008 The three-carbon ring expansion methodology commences with the preparation of a cyclic allene (C9, C11, C13), readily available from the corresponding cycloalkene via dibromocarbene addition and subsequent treatment with methyllithium. Carbon 10-16 RNA polymerase III subunit K Homo sapiens 99-102 18560472-2 2008 The three-carbon ring expansion methodology commences with the preparation of a cyclic allene (C9, C11, C13), readily available from the corresponding cycloalkene via dibromocarbene addition and subsequent treatment with methyllithium. Carbon 10-16 homeobox C13 Homo sapiens 104-107 17932993-2 2008 The objectives of the study were to investigate the association between MTHFR c.677C>T polymorphism and AD in Korean elders and to the extent to which it is modified by the major components of one-carbon metabolism and apolipoprotein E (APOE) genotype. Carbon 197-203 methylenetetrahydrofolate reductase Homo sapiens 72-77 18234742-10 2008 Net hepatic carbon retention was enhanced in NPY vs. control (22 +/- 2 vs. 14 +/- 2 micromol.kg(-1).min(-1), P < 0.05). Carbon 12-18 neuropeptide Y Canis lupus familiaris 45-48 18271575-7 2008 Such BDE lowering in [CoIII(Pc*)]-Me- arises from the involvement of two electronic states: upon electron addition, a quasi-degenerate pi*Pc state is initially formed, but when the cobalt-carbon bond is stretched, the unpaired electron moves to a sigma*Co-C state and the final cleavage involves the three-electron (sigma)2(sigma*)1 bond. Carbon 188-194 homeobox D13 Homo sapiens 5-8 18093821-4 2008 An amperometric glucose biosensor was developed by adsorption of glucose oxidase (GOx) on an AuNPs-AgCl@PANI modified glassy carbon (GC) electrode. Carbon 125-131 hydroxyacid oxidase 1 Homo sapiens 65-80 18093821-4 2008 An amperometric glucose biosensor was developed by adsorption of glucose oxidase (GOx) on an AuNPs-AgCl@PANI modified glassy carbon (GC) electrode. Carbon 125-131 hydroxyacid oxidase 1 Homo sapiens 82-85 18032055-7 2008 These results suggest that elongation of the side chain in 22-thia analogs by up to one carbon can be stably accommodated in the VDR ligand binding pocket. Carbon 88-94 vitamin D receptor Homo sapiens 129-132 18029444-9 2008 Net hepatic carbon retention during P2 was significantly lower in PoSin-1 than SAL or PeSin-1 (21.4 +/- 1.2 vs. 27.1 +/- 1.5 and 26.1 +/- 1.0 mumol.kg(-1).min(-1)). Carbon 12-18 period circadian regulator 2 Homo sapiens 36-38 21817549-0 2008 On-chip deposition of carbon nanotubes using CMOS microhotplates. Carbon 22-28 MOS proto-oncogene, serine/threonine kinase Homo sapiens 45-49 21817549-1 2008 The direct deposition of carbon nanotubes on CMOS microhotplates is demonstrated in this paper. Carbon 25-31 MOS proto-oncogene, serine/threonine kinase Homo sapiens 45-49 21817549-2 2008 Tungsten microhotplates, fabricated on thin SOI membranes aside CMOS control circuitry, are used to locally grow carbon nanotubes by chemical vapour deposition. Carbon 113-119 MOS proto-oncogene, serine/threonine kinase Homo sapiens 64-68 21817549-5 2008 This allows carbon nanotubes to be grown alongside CMOS circuitry on the same wafer without any external heating, thus enabling new applications (e.g. smart gas sensing) where the integration of CMOS and carbon nanotubes is required. Carbon 12-18 MOS proto-oncogene, serine/threonine kinase Homo sapiens 195-199 18063859-7 2008 RESULTS: C311S and G148A polymorphisms of PON2 exist in Chinese people, with the allele frequencies 0.273/0.727 for C/S and 0.567/0.433 for G/A. Carbon 9-10 paraoxonase 2 Homo sapiens 42-46 17999396-9 2008 By using rotor-synchronous double resonance (rotational echo double resonance of X cluster; RDX) experiments, we deduced the distance between the fluorine atom and its nearest carbon atom in the heptaene moiety of 2 to be less than 8.6 A. Carbon 176-182 radixin Homo sapiens 92-95 18200640-0 2008 Creation of hierarchical carbon nanotube assemblies through alternative packing of complementary semi-artificial beta-1,3-glucan/carbon nanotube composites. Carbon 25-31 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 113-121 17918758-6 2008 A number of transition states have been calculated for the enantioselective fluorination by N-fluorobenzenesulfonimide (NFSI) and based on the transition-state energies it has been found that the enantioselectivity depends on the orientation of the C==C bond, being anti or syn, relative to the 2-substituent on the pyrrolidine ring, rather than the approach of the electrophilic fluorine to the face of the reacting carbon atom in the enamine which is less shielded relative to the face with the highest shielding. Carbon 417-423 synemin Homo sapiens 274-277 18200849-7 2007 Individual BDE congeners, sigma9PBDEs, and PBDE 209, were significantly correlated with total organic carbon (TOC), and a good regression (except for BDE 47) between the logarithms of TOC-normalized BDE average concentrations and their log K(ow) was also obtained, indicating that sorption of PBDEs on soil organic matter governed their spatial distribution, transportation, and fate in the soils. Carbon 102-108 homeobox D13 Homo sapiens 11-14 18200849-7 2007 Individual BDE congeners, sigma9PBDEs, and PBDE 209, were significantly correlated with total organic carbon (TOC), and a good regression (except for BDE 47) between the logarithms of TOC-normalized BDE average concentrations and their log K(ow) was also obtained, indicating that sorption of PBDEs on soil organic matter governed their spatial distribution, transportation, and fate in the soils. Carbon 102-108 homeobox D13 Homo sapiens 33-36 18200849-7 2007 Individual BDE congeners, sigma9PBDEs, and PBDE 209, were significantly correlated with total organic carbon (TOC), and a good regression (except for BDE 47) between the logarithms of TOC-normalized BDE average concentrations and their log K(ow) was also obtained, indicating that sorption of PBDEs on soil organic matter governed their spatial distribution, transportation, and fate in the soils. Carbon 102-108 homeobox D13 Homo sapiens 33-36 18271489-2 2007 A theoretical survey of CF2 derivatives of C60 demonstrates that carbon cage opening can be controlled via charging of the molecule and that the thermodynamically preferable structures combine the trend to form open isomers with the compactness of the addition motifs, which results in the formation of windows in the fullerene cage. Carbon 65-71 ATPase H+ transporting accessory protein 1 Homo sapiens 24-27 17891388-6 2007 The alpha-amylase activity using raw corn starch was more than 2.5 times higher than that using glucose as the sole carbon source during L-lysine fermentation. Carbon 116-122 alpha-amylase Zea mays 4-17 17658582-4 2007 Adsorption of surfactant onto activated carbon showed a constant maximum above the critical micelle concentration, which were 0.30, 0.23, 0.15 g g(-1) for D20, D12, and D4, respectively. Carbon 40-46 unconventional SNARE in the ER 1 Homo sapiens 160-163 17658582-7 2007 The highest selectivity was 74.9, 57.3, and 38.3 for D20, D12, and D4, respectively, at the initial conditions of 10 mg l(-1) phenanthrene, 5 g l(-1) Triton X-100 and 1g l(-1) activated carbon. Carbon 186-192 unconventional SNARE in the ER 1 Homo sapiens 58-61 18047100-2 2007 A simple one-step heat treatment has been employed with control of heating temperature and heated LiFePO4 at 650 degrees C exhibited higher 125 mA h/g of the discharge capacity than 600 degrees C, 700 degrees C. To improve conductivity of the inter-particle, carbon coating was carried out by raw carbon or pyrene as carbon sources and their morphological properties of particles on the carbon coating was compared with by FE-SEM, TEM. Carbon 259-265 MFT2 Homo sapiens 431-434 20641787-14 2004 The ligand contains two chiral carbons at C-13 and C-14, therefore, the product is a racemic mixture of (13R, 14S)- and (13S, 14R)-. Carbon 31-38 homeobox C13 Homo sapiens 42-46 17127052-2 2007 To enhance this carbon source utilization and increase the rate of alcohol production, we pretreated corn soluble starch with alpha-amylase. Carbon 16-22 alpha-amylase Zea mays 126-139 17696178-5 2007 As beta-1,3-glucan polysaccharides are known to serve as "polymeric" hosts, including certain DNA molecules, carbon nanotubes, and conjugated polymers, and complexation occurs only with the single-stranded structure, this information is very useful for the creation of these attractive polymeric composites, the controlled release of DNA, and so on. Carbon 109-115 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 3-11 17559287-2 2007 This three-terminal configuration allows the resistance to the source and drain electrodes to be individually measured, which we exploit to demonstrate that electrons were added to spin-degenerate states of the carbon nanotube. Carbon 211-217 spindlin 1 Homo sapiens 181-185 17849370-7 2007 We here report, for the first time, that the prosthetic material surface (non-phagocytable) of as-cast high carbon CoCrMo reduces the pro-inflammatory cytokine IL-6 transcription, the chemokine MCP-1 secretion, and M-CSF secretion by 77%, 36%, and 62%, respectively. Carbon 108-114 colony stimulating factor 1 (macrophage) Mus musculus 215-220 17690534-10 2007 The genes showing significantly lower expressions after X-ray irradiation rather than after carbon-ion beam irradiation were RAD50, BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. Carbon 92-98 BRCA1 DNA repair associated Homo sapiens 132-137 17690534-10 2007 The genes showing significantly lower expressions after X-ray irradiation rather than after carbon-ion beam irradiation were RAD50, BRCA1, MRE11A, XRCC3, CHEK1, MLH1, CCNB1, CCNB2 and LIG4. Carbon 92-98 X-ray repair cross complementing 3 Homo sapiens 147-152 17627676-2 2007 It is cleaved by phospholipase A2 (PLA)(2) to a greater extent than similar compounds with linkers of 2, 3, and 4 carbons. Carbon 114-121 phospholipase A2, group IB, pancreas Mus musculus 17-33 17215118-1 2007 Three amperometric biosensors based on immobilization of tyrosinase on a new Sonogel-Carbon electrode for detection of phenols and polyphenols are described. Carbon 85-91 tyrosinase Homo sapiens 57-67 17215118-8 2007 It was found that the three developed tyrosinase Sonogel-Carbon based biosensors are in satisfactory competitiveness for phenolic compounds determination with other tyrosinase based biosensors reported in the literature. Carbon 57-63 tyrosinase Homo sapiens 38-48 17215118-8 2007 It was found that the three developed tyrosinase Sonogel-Carbon based biosensors are in satisfactory competitiveness for phenolic compounds determination with other tyrosinase based biosensors reported in the literature. Carbon 57-63 tyrosinase Homo sapiens 165-175 17215118-11 2007 An exploratory application to real samples such as beers, river waters and tannery wastewaters showed the ability of the developed Nafion/tyrosinase/Sonogel-Carbon biosensor to retain its stable and reproducible response. Carbon 157-163 tyrosinase Homo sapiens 138-148 17511474-5 2007 Spectral changes associated with the 1-LSD1 complex and reactivity to decreased pH and sodium borohydride treatment were suggestive of a structure involving a flavin-linked inhibitor conjugate between N5 of the flavin and the terminal carbon of the inhibitor. Carbon 235-241 lysine demethylase 1A Homo sapiens 39-43 17350032-0 2007 An amperometric immunosensor for separation-free immunoassay of CA125 based on its covalent immobilization coupled with thionine on carbon nanofiber. Carbon 132-138 mucin 16, cell surface associated Homo sapiens 64-69 17350032-2 2007 The acidic oxidation of the carbon nanofiber provided its solubility and wettability for convenient preparation of a porous carbon nanofiber membrane and a larger number of active sites for covalent binding of carcinoma antigen-125 (CA125) and thionine as electron transfer mediator. Carbon 28-34 mucin 16, cell surface associated Homo sapiens 210-231 17350032-2 2007 The acidic oxidation of the carbon nanofiber provided its solubility and wettability for convenient preparation of a porous carbon nanofiber membrane and a larger number of active sites for covalent binding of carcinoma antigen-125 (CA125) and thionine as electron transfer mediator. Carbon 28-34 mucin 16, cell surface associated Homo sapiens 233-238 17321747-2 2007 The allylic alcohol portion comprising the C-3, C-4, and C-5 carbons is essential for this function. Carbon 61-68 complement C3 Homo sapiens 43-46 17381748-2 2007 METHODS AND RESULTS: Carbon and nitrogen sources and growth factors, such as amino acids and vitamins, were screened initially in a mineral medium for the biomass and antagonistic compound of Pseudomonas MCCB 103. Carbon 21-27 methylcrotonyl-CoA carboxylase subunit 2 Homo sapiens 204-208 17450933-3 2007 The electrocatalytic properties of the MWNTs-Pt-Nafion-GOx nanobiocomposite film modified glassy carbon electrode were characterized by cyclic voltammetry and amperometry in the presence of hydrogen peroxide. Carbon 97-103 hydroxyacid oxidase 1 Homo sapiens 55-58 17445553-9 2007 Sparse sample algorithms used to estimate 12-hour AUC including C(0), C(1), C(2), C(3), C(4), and/or C(6) showed a good correlation with the calculated AUC(0-6) (r(2) = .81-.96). Carbon 52-53 complement C3 Homo sapiens 82-86 17132067-6 2007 The frequency of the C = C stretching mode was modulated by the torsion mode of the C13 = C14 double bond with a period of 200 fs. Carbon 21-22 homeobox C13 Homo sapiens 84-87 17132067-6 2007 The frequency of the C = C stretching mode was modulated by the torsion mode of the C13 = C14 double bond with a period of 200 fs. Carbon 25-26 homeobox C13 Homo sapiens 84-87 17270400-1 2007 In the cerebral prefrontal cortex (PFC), DNA-methyltransferase 1 (DNMT1), the enzyme that catalyzes the methylation of cytosine at carbon atoms in position 5 in CpG dinucleotides, is expressed selectively in GABAergic neurons and is upregulated in layers I and II of schizophrenia (SZ) and bipolar disorder patients with psychosis (BDP). Carbon 131-137 DNA methyltransferase 1 Homo sapiens 41-64 17067719-2 2007 The organisms in mulch breakdown complex organics to soluble carbon, which can then be used by these and other microorganisms as an electron donor for treating RDX and HMX via reductive pathways. Carbon 61-67 radixin Homo sapiens 160-163 17053001-2 2007 Methylenetetrahydrofolate reductase (MTHFR) regulates the flow of folic acid-derived, one-carbon moieties for methylation and is critical to early embryonic development. Carbon 90-96 methylenetetrahydrofolate reductase Homo sapiens 0-35 17053001-2 2007 Methylenetetrahydrofolate reductase (MTHFR) regulates the flow of folic acid-derived, one-carbon moieties for methylation and is critical to early embryonic development. Carbon 90-96 methylenetetrahydrofolate reductase Homo sapiens 37-42 17257263-10 2007 Eliminating formation of glycerol through FPS1 deletion can be used to increase ethanol yield of S. cerevisiae without increasing the overall cost of carbon source. Carbon 150-156 Fps1p Saccharomyces cerevisiae S288C 42-46 17210948-4 2007 Puf3p levels are reduced during the diauxic shift and growth on a nonfermentable carbon source, conditions that stimulate mitochondrial biogenesis. Carbon 81-87 mRNA-binding protein PUF3 Saccharomyces cerevisiae S288C 0-5 16838112-9 2007 Biodistribution studies showed that the BN analog with the 8-carbon linker not only had the highest tumor uptake but also had high normal tissue uptake in the liver. Carbon 61-67 gastrin releasing peptide Homo sapiens 40-42 16134079-1 2007 Methylenetetrahydrofolate reductase (MTHFR) is an enzyme (EC 1.5.1.20), that reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a carbon donor for the homocysteine to methionine conversion. Carbon 147-153 methylenetetrahydrofolate reductase Homo sapiens 0-35 16134079-1 2007 Methylenetetrahydrofolate reductase (MTHFR) is an enzyme (EC 1.5.1.20), that reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a carbon donor for the homocysteine to methionine conversion. Carbon 147-153 methylenetetrahydrofolate reductase Homo sapiens 37-42 17313137-1 2007 A dynamic coating of the RP-18 carbon chain layers with the new chiral selector (S)-(-)-alpha,alpha-di(2-naphthyl)-2-pyrrolidinemethanol allowed the formation of a mixed chiral stationary phase that has been used in the separation of a selected set of amino acid racemates. Carbon 31-37 pre-mRNA processing factor 3 Homo sapiens 25-30 17021052-7 2007 Most acylcarnitines were increased in V1aR-/- mice, especially in the case of 2-carbon (C2), C10:1, C10, C14:1, C16, C18:1, and hydroxy-18:1-carbon (OH-C18:1)-acylcarnitines under feeding rather than under fasting conditions. Carbon 80-86 arginine vasopressin receptor 1A Mus musculus 38-45 17284458-0 2007 Interplay between CRP-cAMP and PII-Ntr systems forms novel regulatory network between carbon metabolism and nitrogen assimilation in Escherichia coli. Carbon 86-92 catabolite gene activator protein Escherichia coli 18-21 16962989-3 2006 During the relaxation process, the kinetics of the reversal of this conformation is coupled to the closing of the Ca(2+)-induced open conformation of the N-domain of troponin C (cTnC) and an interaction between cTnC and cTnI in their interface. Carbon 114-115 troponin I3, cardiac type Homo sapiens 220-224 17132742-5 2006 Transgenic plants with suppressed sorbitol-6-phosphate dehydrogenase compensated by accumulating sucrose and starch in leaves, and morning and midday net carbon assimilation rates were significantly lower. Carbon 154-160 NADP-dependent D-sorbitol-6-phosphate dehydrogenase Malus domestica 34-68 17304849-1 2006 PBS, a new kind of biodegradable polymers (BDPs), can be used as carbon source and biofilm carrier to remove nitrate from drinking water source. Carbon 65-71 translocator protein Homo sapiens 0-3 17011626-1 2006 Yeast cytochrome c peroxidase (CCP) efficiently catalyzes the reduction of H(2)O(2) to H(2)O by ferrocytochrome c in vitro. Carbon 6-7 cytochrome-c peroxidase Saccharomyces cerevisiae S288C 31-34 17011626-3 2006 CCP1-null-mutant cells in the W303-1B genetic background (ccp1Delta) grew as well as wild-type cells with glucose, ethanol, glycerol or lactate as carbon sources but with a shorter initial doubling time. Carbon 147-153 cytochrome-c peroxidase Saccharomyces cerevisiae S288C 0-4 17159642-2 2006 METHODS: We applied results from a case-control study to adjust the SMR for smoking habits and exposures experienced before the carbon black job. Carbon 128-134 LY6/PLAUR domain containing 4 Homo sapiens 68-71 16751223-0 2006 Ultrafine carbon particles induce apoptosis and proliferation in rat lung epithelial cells via specific signaling pathways both using EGF-R. Carbon 10-16 epidermal growth factor receptor Rattus norvegicus 134-139 16986836-1 2006 Squaric acid dimethyl ester (C(6)O(4)H(6); 3,4-dimethoxycyclobut-3-ene-1,2-dione; DCD) was studied by matrix isolation infrared spectroscopy and by density functional theory (B3LYP) and ab initio (MP2) calculations with the 6-31++G(d,p) and 6-311++G(d,p) basis sets. Carbon 29-30 dermcidin Homo sapiens 82-85 16999495-1 2006 In this work, using quantum partial charges, computed from 6-31G(**)B3LYP density functional theory, in molecular dynamics simulations, we found that water inside (6,6) and (10,0) single-walled carbon nanotubes with similar diameters but with different chiralities has remarkably different structural and dynamical properties. Carbon 194-200 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 70-73 16800010-1 2006 Compounds containing the C==N group, such as imines and their derivatives, may undergo syn-anti isomerization by two different routes: 1) photochemically, by out-of-plane rotation around the carbon-nitrogen double bond through a "perpendicular" form, and 2) thermally, by in-plane nitrogen inversion through a "linear" transition state. Carbon 191-197 synemin Homo sapiens 87-90 22266618-1 2006 OBJECTIVE: To investigate the association of the 2 intracellular adhesion molecules-1 (ICAM-1) gene polymorphisms [thymidine/cytidine (T/C) 469 and guanosine/adenosine (G/A) 241] in Behcet`s disease in Lebanon. Carbon 4-5 intercellular adhesion molecule 1 Homo sapiens 87-93 16495062-1 2006 The previous exploration of the structure-affinity relationships concerning 4-phenyl-2-quinolinecarboxamide peripheral benzodiazepine receptor (PBR) ligands 6 showed as an interesting result the importance of the presence of a chlorine atom in the methylene carbon at position 3 of the quinoline nucleus. Carbon 258-264 translocator protein Rattus norvegicus 108-142 16495062-1 2006 The previous exploration of the structure-affinity relationships concerning 4-phenyl-2-quinolinecarboxamide peripheral benzodiazepine receptor (PBR) ligands 6 showed as an interesting result the importance of the presence of a chlorine atom in the methylene carbon at position 3 of the quinoline nucleus. Carbon 258-264 translocator protein Rattus norvegicus 144-147 16734787-2 2006 However, when the fadD gene from E. coli MG1655 was expressed in E. coli DH5alpha, the latter strain was found to utilize medium-chain fatty acids as its sole carbon source. Carbon 159-165 long-chain-fatty-acid--CoA ligase Escherichia coli str. K-12 substr. MG1655 18-22 16734787-3 2006 Various E. coli strains thought to carry subtly different FadR phenotypes were all confirmed as using medium-chain fatty acids as their sole carbon source when the additional fadD was expressed. Carbon 141-147 long-chain-fatty-acid--CoA ligase Escherichia coli str. K-12 substr. MG1655 175-179 16439134-4 2006 Spin adducts from other oxygen- and carbon-centered radicals (e.g., derived from methanol or linoleic acid hydroperoxide) are also described. Carbon 36-42 spindlin 1 Homo sapiens 0-4 16770051-4 2006 The method is based on the preconcentration of the complexes of beryllium-acetylacetone plus morin, oxine, PAN and PAR on activated carbon at different pH values. Carbon 132-138 jumping translocation breakpoint Homo sapiens 115-118 16597938-1 2006 Hydrophobic surface binding protein A (HsbA) is a secreted protein (14.5 kDa) isolated from the culture broth of Aspergillus oryzae RIB40 grown in a medium containing polybutylene succinate-co-adipate (PBSA) as a sole carbon source. Carbon 218-224 hypothetical protein Aspergillus oryzae RIB40 0-37 16597938-1 2006 Hydrophobic surface binding protein A (HsbA) is a secreted protein (14.5 kDa) isolated from the culture broth of Aspergillus oryzae RIB40 grown in a medium containing polybutylene succinate-co-adipate (PBSA) as a sole carbon source. Carbon 218-224 hypothetical protein Aspergillus oryzae RIB40 39-43 16397765-5 2006 We demonstrated that HXT5, HXT13 and, to a lesser extent, HXT15 were all induced in the presence of non-fermentable carbon sources. Carbon 116-122 hexose transporter HXT13 Saccharomyces cerevisiae S288C 27-32 16402205-3 2006 Here, we show that CPC2 transcription depends on the carbon source and is induced during utilization of the sugar glucose. Carbon 53-59 guanine nucleotide-binding protein subunit beta Saccharomyces cerevisiae S288C 19-23 16402205-6 2006 Deletion of FHL1 reduces CPC2 transcription significantly in presence of glucose, but has no effect when the non-fermentable carbon source ethanol is provided. Carbon 125-131 Fhl1p Saccharomyces cerevisiae S288C 12-16 16402205-8 2006 These data suggest that the interaction between Fhl1p and Ifh1p is critical for the regulation of CPC2 transcription during utilization of different carbon sources. Carbon 149-155 Fhl1p Saccharomyces cerevisiae S288C 48-53 16402205-8 2006 These data suggest that the interaction between Fhl1p and Ifh1p is critical for the regulation of CPC2 transcription during utilization of different carbon sources. Carbon 149-155 guanine nucleotide-binding protein subunit beta Saccharomyces cerevisiae S288C 98-102 16525545-3 2006 Its structure has 18 chiral centres common with erythromycin A, but C-9 (the spiro carbon) is also chiral in anhydroerythromycin and its stereochemistry has not previously been reported; both 9R- and 9S-anhydroerythromycin A are plausible structures. Carbon 83-89 complement C9 Homo sapiens 68-71 16509569-3 2006 In light of the crystal structures of the vitamin D nuclear receptor (VDR), novel analogues of the hormone 1alpha,25(OH)2D3 with side chains attached to C-12 were synthesized via the convergent Wittig-Horner approach. Carbon 153-154 vitamin D receptor Homo sapiens 42-68 16509569-3 2006 In light of the crystal structures of the vitamin D nuclear receptor (VDR), novel analogues of the hormone 1alpha,25(OH)2D3 with side chains attached to C-12 were synthesized via the convergent Wittig-Horner approach. Carbon 153-154 vitamin D receptor Homo sapiens 70-73 16415064-0 2006 Contribution of fructose-1,6-bisphosphatase and sedoheptulose-1,7-bisphosphatase to the photosynthetic rate and carbon flow in the Calvin cycle in transgenic plants. Carbon 112-118 fructose-1,6-bisphosphatase, cytosolic-like Nicotiana tabacum 16-43 16415064-1 2006 To clarify the contributions of fructose-1,6-bisphosphatase (FBPase) and sedoheptulose-1,7-bisphosphatase (SBPase) separately to the carbon flux in the Calvin cycle, we generated transgenic tobacco plants expressing cyanobacterial FBPase-II in chloroplasts (TpF) or Chlamydomonas SBPase in chloroplasts (TpS). Carbon 133-139 fructose-1,6-bisphosphatase, cytosolic-like Nicotiana tabacum 231-237 16415064-7 2006 These data indicated that the enhancement of either a >1.7-fold increase of FBPase or a 1.3-fold increase of SBPase in the chloroplasts had a marked positive effect on photosynthesis, that SBPase is the most important factor for the RuBP regeneration in the Calvin cycle and that FBPase contributes to the partitioning of the fixed carbon for RuBP regeneration or starch synthesis. Carbon 335-341 fructose-1,6-bisphosphatase, cytosolic-like Nicotiana tabacum 79-85 16629272-0 2006 Enhanced desorption of RDX from granular activated carbon. Carbon 51-57 radixin Homo sapiens 23-26 16629272-1 2006 Several methods (cosolvents, surfactants, and cyclodextrins) were compared for improving desorption of a high explosive, RDX, from granular activated carbon (GAC). Carbon 150-156 radixin Homo sapiens 121-124 16384546-2 2006 The low-isoelectric point tyrosinase was adsorbed on the surface of high-isoelectric point ZnO nanoparticles (nano-ZnO) facilitated by the electrostatic interactions and then immobilized on the glassy carbon electrode via the film forming by chitosan. Carbon 201-207 tyrosinase Homo sapiens 26-36 16441363-6 2006 There were increases of ALK-p (C: 67.4 +/- 32.9 to 79.6 +/- 37.0*; N: 67.3 +/- 25.1 to 67.8 +/- 14.7 IU) (*P < 0.05), Ca(2+) (C: 8.7 +/- 0.3 to 9.5 +/- 0.2*; N: 8.8 +/- 0.4 to 8.7 +/- 0.5 mg/dl), urinary P excretion (C: 287.6 +/- 257.1 to 439.4 +/- 260.9*; N: 233.9 +/- 117.2 to 264.8 +/- 143.4 mg/day) and iPTH (C: 133.7 +/- 149.6 to 200.6 +/- 171.5*; N: 128.4 +/- 57.1 to 136.3 +/- 40.4 pg/ml). Carbon 31-32 ALK receptor tyrosine kinase Homo sapiens 24-27 16171920-2 2006 Affinity to soil and persistence of PCBs have been shown to increase with increasing soil organic carbon (OC) content, PCB chlorination, and PCB coplanarity. Carbon 98-104 pyruvate carboxylase Rattus norvegicus 36-39 16504293-9 2006 Moreover, polyinosinic polycytidylic acid (poly I:C) induced increased GBP transcript levels in RTS11 and RTG2 cells after 4-6 h of stimulation, and in head kidney and liver of live fish after 24 h. These studies suggest that rbtGBP is an early response gene in rainbow trout, which may have similar functions in IFN-gamma mediated responses as mammalian GBPs. Carbon 50-51 glycogen synthase kinase binding protein Oncorhynchus mykiss 71-74 16796018-6 2006 In a third step the peroxisomal 2-hydroxyphytanoyl-CoA lyase (2-HPCL) splits the carbon carbon bond of the 2-hydroxy-intermediate into a 2-methyl(n-1)aldehyde and formyl-CoA, which is subsequently converted to formate and CO2. Carbon 81-87 2-hydroxyacyl-CoA lyase 1 Homo sapiens 32-60 16796018-6 2006 In a third step the peroxisomal 2-hydroxyphytanoyl-CoA lyase (2-HPCL) splits the carbon carbon bond of the 2-hydroxy-intermediate into a 2-methyl(n-1)aldehyde and formyl-CoA, which is subsequently converted to formate and CO2. Carbon 81-87 2-hydroxyacyl-CoA lyase 1 Homo sapiens 62-68 16796018-6 2006 In a third step the peroxisomal 2-hydroxyphytanoyl-CoA lyase (2-HPCL) splits the carbon carbon bond of the 2-hydroxy-intermediate into a 2-methyl(n-1)aldehyde and formyl-CoA, which is subsequently converted to formate and CO2. Carbon 88-94 2-hydroxyacyl-CoA lyase 1 Homo sapiens 32-60 16796018-6 2006 In a third step the peroxisomal 2-hydroxyphytanoyl-CoA lyase (2-HPCL) splits the carbon carbon bond of the 2-hydroxy-intermediate into a 2-methyl(n-1)aldehyde and formyl-CoA, which is subsequently converted to formate and CO2. Carbon 88-94 2-hydroxyacyl-CoA lyase 1 Homo sapiens 62-68 16323906-4 2005 Both the syn and anti macrocycles show close contacts between the arsenic(III) ions and the aromatic carbons, consistent with intramolecular arsenic-pi interactions. Carbon 101-108 synemin Homo sapiens 9-12 18970285-0 2005 MCM-41 mesoporous material modified carbon paste electrode for the determination of cardiac troponin I by anodic stripping voltammetry. Carbon 36-42 troponin I3, cardiac type Homo sapiens 84-102 16211374-6 2005 In the presence of multiple or IA-2 antibodies, a PI:C ratio exceeding percentile 66 of all antibody-negative relatives at entry (n=784) conferred a 5-year diabetes risk of 50% and 68%, respectively (p<0.001 vs 13% for same antibody status with PI:C<percentile 66). Carbon 53-54 protein tyrosine phosphatase receptor type N Homo sapiens 31-35 16370225-3 2005 An emerging body of in vitro and clinical evidence suggests that these MTHFR SNPs may be an important pharmacogenetic determinant of predicting response to and toxicity of methotrexate and 5-fluorouracil-based cancer and anti-inflammatory treatments because of their well-defined and highly relevant biochemical effects on intracellular folate composition and one-carbon transfer reactions. Carbon 364-370 methylenetetrahydrofolate reductase Homo sapiens 71-76 16262716-8 2005 A transcript profiling experiment revealed that a considerable proportion of genes downregulated in the loss-of-function mutants are involved in carbon metabolism and At5g56860 is thus designated GNC (GATA, nitrate-inducible, carbon metabolism-involved). Carbon 145-151 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 196-199 16262716-8 2005 A transcript profiling experiment revealed that a considerable proportion of genes downregulated in the loss-of-function mutants are involved in carbon metabolism and At5g56860 is thus designated GNC (GATA, nitrate-inducible, carbon metabolism-involved). Carbon 226-232 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 196-199 16262716-10 2005 These observations suggest a function for GNC in regulating carbon and nitrogen metabolism. Carbon 60-66 GATA type zinc finger transcription factor family protein Arabidopsis thaliana 42-45 16246394-0 2005 Removing low ppb level perchlorate, RDX, and HMX from groundwater with cetyltrimethylammonium chloride (CTAC) pre-loaded activated carbon. Carbon 131-137 radixin Homo sapiens 36-39 16392473-0 2005 Spin-unrestricted linear-scaling electronic structure theory and its application to magnetic carbon-doped boron nitride nanotubes. Carbon 93-99 spindlin 1 Homo sapiens 0-4 16039863-14 2005 The biological activity of these analogs also suggests the necessity of an unsaturated C-8-C-9 bridge for dual RTK and DHFR inhibitory activity. Carbon 87-88 dihydrofolate reductase Mus musculus 119-123 16112640-8 2005 The mutant CYP4F8 Gly328Glu oxidized U-51605 and U-44069 as recombinant CYP4F8, but the hydroxylation of arachidonic acid was shifted from C-18 to C-19. Carbon 11-12 cytochrome P450 family 4 subfamily F member 8 Homo sapiens 72-78 16112640-8 2005 The mutant CYP4F8 Gly328Glu oxidized U-51605 and U-44069 as recombinant CYP4F8, but the hydroxylation of arachidonic acid was shifted from C-18 to C-19. Carbon 72-73 cytochrome P450 family 4 subfamily F member 8 Homo sapiens 11-17 16853120-4 2005 Electron microscopy (SEM, TEM) and thermal gravimetric analysis (TGA) indicated that the catalytically grown carbon had relatively little thermal over-growth and possessed either a herringbone or a semi-ordered nanostructure, depending on the growth conditions. Carbon 109-115 MFT2 Homo sapiens 26-29 16050675-2 2005 Dicyclohexylcarbodiimide (CyN=C=NCy, DCC) promotes the facile formation of organic carbonates from aliphatic alcohols and carbon dioxide at temperatures as low as 310 K and moderate pressure of CO2 (from 0.1 MPa) with an acceptable rate. Carbon 26-27 DCC netrin 1 receptor Homo sapiens 37-40 15927466-2 2005 Analogues that incorporated a bulky substituent at the first carbon position of benzylamine or isoquinoline showed over 30-fold selectivity for DPP-IV over both DPP8 and DPP-II. Carbon 61-67 dipeptidyl peptidase 8 Homo sapiens 161-165 15949974-0 2005 Contribution of the Saccharomyces cerevisiae transcriptional regulator Leu3p to physiology and gene expression in nitrogen- and carbon-limited chemostat cultures. Carbon 128-134 leucine-responsive transcriptional regulator LEU3 Saccharomyces cerevisiae S288C 71-76 15831494-13 2005 Finally, this analysis provided evidence that Pak1 functions in another capacity, besides activating Snf1, to regulate the nuclear enrichment of Snf1 protein kinase in response to carbon stress. Carbon 180-186 serine/threonine protein kinase SAK1 Saccharomyces cerevisiae S288C 46-50 16123070-3 2005 Under 20-100 mTorr of gas pressures at 480 degrees C, serpentine-shaped or zigzag, multi-wall carbon nanotubes grew at an average rate of 35-40 nm sec(-1). Carbon 94-100 secretory blood group 1, pseudogene Homo sapiens 147-153 16123070-4 2005 At pressures <10 mTorr at the same temperature, straight single-wall carbon nanotubes with nearly uniform diameters (approximately 3.5 nm) formed at average growth rates of 6-9 nm sec(-1). Carbon 72-78 secretory blood group 1, pseudogene Homo sapiens 183-189 15767269-2 2005 Sink growth drives the competition for carbon, nutrients and water within the plant, and determines the structure of leaves and roots that supply resources to the plant later on. Carbon 39-45 tribbles pseudokinase 3 Homo sapiens 0-4 15879520-0 2005 Role of Tos3, a Snf1 protein kinase kinase, during growth of Saccharomyces cerevisiae on nonfermentable carbon sources. Carbon 104-110 serine/threonine protein kinase TOS3 Saccharomyces cerevisiae S288C 8-12 15753106-7 2005 These results suggest that ASML1/WRI1 is a transcriptional activator involved in the activation of a subset of sugar-responsive genes and the control of carbon flow from sucrose import to oil accumulation in developing seeds. Carbon 153-159 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 27-32 15753106-7 2005 These results suggest that ASML1/WRI1 is a transcriptional activator involved in the activation of a subset of sugar-responsive genes and the control of carbon flow from sucrose import to oil accumulation in developing seeds. Carbon 153-159 Integrase-type DNA-binding superfamily protein Arabidopsis thaliana 33-37 15653696-12 2005 A TSG-6 hydroxyl group reacts with the ester bond between the alpha-carbonyl of the C-terminal Asp residues of HC1 or HC2 and carbon-6 of an internal N-acetylgalactosamine of the chondroitin-4-sulfate chain. Carbon 68-74 TNF alpha induced protein 6 Homo sapiens 2-7 15653696-12 2005 A TSG-6 hydroxyl group reacts with the ester bond between the alpha-carbonyl of the C-terminal Asp residues of HC1 or HC2 and carbon-6 of an internal N-acetylgalactosamine of the chondroitin-4-sulfate chain. Carbon 68-74 CYCS pseudogene 39 Homo sapiens 111-114 15653696-12 2005 A TSG-6 hydroxyl group reacts with the ester bond between the alpha-carbonyl of the C-terminal Asp residues of HC1 or HC2 and carbon-6 of an internal N-acetylgalactosamine of the chondroitin-4-sulfate chain. Carbon 68-74 CYCS pseudogene 38 Homo sapiens 118-121 16833522-2 2005 The molecules may exist as a mixture of different conformers with the C-Cl bond either syn (torsion angle phi = 0 degrees ) or gauche to the carbonyl bond. Carbon 70-71 synemin Homo sapiens 87-90 15614490-4 2005 Hap4p is the key regulator of the complex activity in response to carbon sources in S. cerevisiae. Carbon 66-72 transcription factor HAP4 Saccharomyces cerevisiae S288C 0-5 15680604-2 2005 The reactivity towards BCl(3) follows the order: C-4>or=C-2>C-6>C-3 for C-glucopyranosyl derivatives and C-3>or=C-4>C-6>C-2 for C-galactopyranosyl derivatives. Carbon 24-25 complement C3 Homo sapiens 73-76 15680604-2 2005 The reactivity towards BCl(3) follows the order: C-4>or=C-2>C-6>C-3 for C-glucopyranosyl derivatives and C-3>or=C-4>C-6>C-2 for C-galactopyranosyl derivatives. Carbon 24-25 complement C3 Homo sapiens 114-117 15659676-0 2005 Functional interactions between the carbon and iron utilization regulators, Crp and Fur, in Escherichia coli. Carbon 36-42 catabolite gene activator protein Escherichia coli 76-79 15659676-1 2005 In Escherichia coli, the ferric uptake regulator (Fur) controls expression of the iron regulon in response to iron availability while the cyclic AMP receptor protein (Crp) regulates expression of the carbon regulon in response to carbon availability. Carbon 200-206 catabolite gene activator protein Escherichia coli 167-170 15659676-3 2005 Many iron transport genes and several carbon metabolic genes are subject to dual control, being repressed by the loss of Crp and activated by the loss of Fur. Carbon 38-44 catabolite gene activator protein Escherichia coli 121-124 15621348-7 2005 Assessment of halogenated organic compounds was made using halogenated organic compounds absorbable on activated carbon (AOX) concentrations. Carbon 113-119 acyl-CoA oxidase 1 Homo sapiens 121-124 15780499-5 2005 Recent studies in breast cancer cells have revealed a bi-directional connection between Her-2/neu and fatty acid synthase (FAS), a major lipogenic enzyme catalyzing the synthesis of long-chain saturated fatty acids from the 2-carbon donors malonyl-CoA and acetyl-CoA. Carbon 226-232 fatty acid synthase Homo sapiens 102-121 15780499-5 2005 Recent studies in breast cancer cells have revealed a bi-directional connection between Her-2/neu and fatty acid synthase (FAS), a major lipogenic enzyme catalyzing the synthesis of long-chain saturated fatty acids from the 2-carbon donors malonyl-CoA and acetyl-CoA. Carbon 226-232 fatty acid synthase Homo sapiens 123-126 15780499-10 2005 Interestingly, while in liver and adipose tissue FAS produces fat from excess carbon consumed as carbohydrates, which is ultimately stored as triglycerides, in epithelial cancer cells, FAS activity is mainly involved in the production of phospholipids partitioning into detergent-resistant membrane microdomains (lipid raft-aggregates), which point to an active role of FAS in the deregulation of membrane functioning in tumor cells. Carbon 78-84 fatty acid synthase Homo sapiens 49-52 15537452-8 2004 Combining the substitutions of Ac(5)c(1) and Aib(3) yielded the highest affinity and most potent PTH(1-14) and shorter-length analogs to date: [Ac(5)c(1), Aib(3),M]PTH(1-X) (X = 14, 11, and 10; IC(50)s = 80 nM, 260 nM, and 850 microM; EC(50)s = 1.7 nM, 3.1 nM, and 1.9 microM, respectively). Carbon 32-33 parathyroid hormone Sus scrofa 97-100 15537452-8 2004 Combining the substitutions of Ac(5)c(1) and Aib(3) yielded the highest affinity and most potent PTH(1-14) and shorter-length analogs to date: [Ac(5)c(1), Aib(3),M]PTH(1-X) (X = 14, 11, and 10; IC(50)s = 80 nM, 260 nM, and 850 microM; EC(50)s = 1.7 nM, 3.1 nM, and 1.9 microM, respectively). Carbon 32-33 parathyroid hormone Sus scrofa 164-167 15488475-0 2004 C-25 hydroxylation of 1alpha,24(R)-dihydroxyvitamin D3 is catalyzed by 25-hydroxyvitamin D3-24-hydroxylase (CYP24A1): metabolism studies with human keratinocytes and rat recombinant CYP24A1. Carbon 0-1 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 108-115 15520229-6 2004 We show that a second threshold is required together with the Cln3/Far1 threshold for carbon source modulation of Ps. Carbon 86-92 cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1 Saccharomyces cerevisiae S288C 67-71 15501569-3 2004 Echi could be accumulated from the solution and give well-defined electrochemical signals in 0.1 M phosphate buffer solution (pH 7.0) only when Gua was present on the surface of the electrochemically pretreated glass carbon electrode (GCE), suggesting a strong binding of Echi to Gua. Carbon 217-223 DExD-box helicase 21 Homo sapiens 144-147 15555906-8 2004 The results support our original proposal that the main role of cytochrome b(5) is to promote protein conformational changes which allow the iron-peroxo anion to form a tetrahedral adduct that fragments to produce the acyl-carbon cleavage products. Carbon 223-229 mitochondrially encoded cytochrome b Homo sapiens 64-76 15226312-4 2004 With the use of unnatural substrates, the regioselectivity of C. elegans FAT-2 was clearly defined as nu+3, i.e. it "measures" three carbons from an existing double bond. Carbon 133-140 Delta(12) fatty acid desaturase fat-2 Caenorhabditis elegans 73-78 15339180-1 2004 Density functional theory calculations (B3LYP/6-31+G) demonstrate that conjugating and electron-donating substituents at carbons three and four of a cyclopentenyl oxyallylic cation should have a rate-accelerating effect on the retro-Nazarov reactions of these species. Carbon 121-128 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 42-45 15301951-0 2004 Direct electron transfer of glucose oxidase promoted by carbon nanotubes. Carbon 56-62 hydroxyacid oxidase 1 Homo sapiens 28-43 15570978-1 2004 Characteristics of carbon deposition by CH4 and carbon elimination by CO2 over conventional and nanoscale Ni/gamma-Al2O3 catalysts were investigated by using a pulse reaction, as well as by TGA, TEM, TPO-MS, H2-TPR and H2-chemisorption techniques. Carbon 19-25 thyroid peroxidase Homo sapiens 200-203 15570978-1 2004 Characteristics of carbon deposition by CH4 and carbon elimination by CO2 over conventional and nanoscale Ni/gamma-Al2O3 catalysts were investigated by using a pulse reaction, as well as by TGA, TEM, TPO-MS, H2-TPR and H2-chemisorption techniques. Carbon 19-25 translocated promoter region, nuclear basket protein Homo sapiens 211-214 15142595-1 2004 The enzyme glucose oxidase (GOx) has been immobilized electrostatically onto carbon and platinum electrodes modified with mixed ferrocene-cobaltocenium dendrimers. Carbon 77-83 hydroxyacid oxidase 1 Homo sapiens 11-26 15142595-1 2004 The enzyme glucose oxidase (GOx) has been immobilized electrostatically onto carbon and platinum electrodes modified with mixed ferrocene-cobaltocenium dendrimers. Carbon 77-83 hydroxyacid oxidase 1 Homo sapiens 28-31 15230614-3 2004 When alk-2-yn-1-ols 9 were allowed to react with selenium and isocyanides under similar conditions, new selenium-containing heterocycles 10, 2-imino-4-alkylidene-1,3-oxaselenolanes, were obtained via cycloaddition of oxyimidoylselenoates 13 generated in situ by intramolecular addition of selenolates to carbon-carbon triple bonds. Carbon 304-310 activin A receptor type 1 Homo sapiens 5-10 15230614-3 2004 When alk-2-yn-1-ols 9 were allowed to react with selenium and isocyanides under similar conditions, new selenium-containing heterocycles 10, 2-imino-4-alkylidene-1,3-oxaselenolanes, were obtained via cycloaddition of oxyimidoylselenoates 13 generated in situ by intramolecular addition of selenolates to carbon-carbon triple bonds. Carbon 311-317 activin A receptor type 1 Homo sapiens 5-10 15110290-3 2004 The best paste composition (enzyme/pyrrole monomer/carbon particles/Nujol) was determined for a model enzyme, glucose oxidase (GOx) according to the enzymatic activity of the resulting electrodes and to the enzyme leakage from the paste during storage in phosphate buffer. Carbon 51-57 hydroxyacid oxidase 1 Homo sapiens 110-125 15136740-2 2004 Here, we apply the plant-specific Dof1 transcription factor to improve nitrogen assimilation, the essential metabolism including the primary assimilation of ammonia to carbon skeletons to biosynthesize amino acids and other organic compounds involving nitrogen in plants. Carbon 168-174 DOF zinc finger protein 1 Arabidopsis thaliana 34-38 15136740-3 2004 Expressing Dof1 induced the up-regulation of genes encoding enzymes for carbon skeleton production, a marked increase of amino acid contents, and a reduction of the glucose level in transgenic Arabidopsis. Carbon 72-78 DOF zinc finger protein 1 Arabidopsis thaliana 11-15 15225755-0 2004 Model of three-dimensional structure of VDR bound with Vitamin D3 analogs substituted at carbon-2. Carbon 89-95 vitamin D receptor Homo sapiens 40-43 14991407-9 2004 This raises the possibility that PEPCK may function in the conversion of these carbon skeletons to PEP, which, depending on the energy requirements of the phloem, is subsequently utilised by either gluconeogenesis or the Krebs cycle, which both consume protons. Carbon 79-85 phosphoenolpyruvate carboxykinase (ATP) Cucumis sativus 33-38 15096047-4 2004 Expression of a processed form of human SUV3 carrying an N-terminal deletion of 46 amino acids (SUV3DeltaN46) in a yeast suv3 null mutant, which otherwise fails to grow in a nonfermentable carbon source and forms petite colonies in glucose medium, rescues the null phenotype. Carbon 189-195 Suv3 like RNA helicase Homo sapiens 40-44 15079839-3 2004 The asymmetric cross-Mannich reactions are highly syn-selective and in several cases the two new carbon centers are formed with absolute stereocontrol. Carbon 97-103 synemin Homo sapiens 50-53 15088759-2 2004 The separation is a result of the whole interaction between the diastereomeric complex surface and the mixed stationary phase realized by the dynamic coating of the RP-18 carbon chains layer. Carbon 171-177 pre-mRNA processing factor 3 Homo sapiens 165-170 15835161-1 2004 Structural characteristics of a series of MAST carbons were studied using scanning electron microscopy images and the nitrogen adsorption isotherms analyzed with several models of pores and different adsorption equations. Carbon 47-54 SPG21 abhydrolase domain containing, maspardin Homo sapiens 42-46 15835161-2 2004 A developed model of pores as a mixture of gaps between spherical nanoparticles and slitlike pores was found appropriate for MAST carbons. Carbon 130-137 SPG21 abhydrolase domain containing, maspardin Homo sapiens 125-129 15835161-5 2004 Cellulose-coated microporous carbon Norit RBX adsorbs significantly smaller amounts of ibuprofen than uncoated micro/mesoporous MAST carbons whose adsorption capability increases with increasing mesoporosity and specific surface area, burnoff dependent variable. Carbon 133-140 SPG21 abhydrolase domain containing, maspardin Homo sapiens 128-132 14711823-3 2004 Escherichia coli has a single ACS, FadD, that is essential for growth when fatty acids are the sole carbon and energy source. Carbon 100-106 Fas associated via death domain Rattus norvegicus 35-39 15052310-5 2004 Using universally labeled (UL)-[14C]RDX, we obtained a carbon mass balance distributed as follows: CO2, 48%-58%; water soluble products, 27%-31%; acetonitrile extractable products, 2.0%-3.4%; and products covalently bound to the sediments and biomass, 8.9% (in the presence of glucose). Carbon 55-61 radixin Homo sapiens 36-39 15306081-6 2004 The ballistic quantum conductance of a multiwalled carbon nanotube was observed at room temperature using the setup in TEM. Carbon 51-57 MFT2 Homo sapiens 119-122 15120130-0 2004 TEM investigation on the growth mechanism of carbon nanotubes synthesized by hot-filament chemical vapor deposition. Carbon 45-51 MFT2 Homo sapiens 0-3 14667785-8 2003 Examples including crambin, cytochrome c, cytochrome B and hemerythrin gave good secondary structure fits with overall alpha carbon atom rms deviations of between 5 and 5.6 A with an optimised hydrophobic term in the fitness function. Carbon 125-131 mitochondrially encoded cytochrome b Homo sapiens 42-54 14633848-8 2003 Tandem mass spectrometry and nuclear magnetic resonance analysis of the product of phosphorylation of 1-deoxy-1-morpholino-psicose by FN3K-RP indicated that this enzyme phosphorylates the third carbon of the sugar moiety. Carbon 194-200 fructosamine 3 kinase related protein Homo sapiens 134-141 14611252-2 2003 The carbon-carbon bond formation is stereospecific, occurring syn with respect to the leaving group. Carbon 4-10 synemin Homo sapiens 62-65 14611252-2 2003 The carbon-carbon bond formation is stereospecific, occurring syn with respect to the leaving group. Carbon 11-17 synemin Homo sapiens 62-65 14598403-12 2003 Therefore carbon-carbon composites, such as P25-CVD, may be important in the development of next-generation implants with lower wear rates and reduced cytotoxic potential. Carbon 10-16 tubulin polymerization promoting protein Homo sapiens 44-51 14598403-12 2003 Therefore carbon-carbon composites, such as P25-CVD, may be important in the development of next-generation implants with lower wear rates and reduced cytotoxic potential. Carbon 17-23 tubulin polymerization promoting protein Homo sapiens 44-51 14576281-3 2003 The level of LKR/SDH was strongly enhanced by ABA, jasmonate, and sugar starvation, whereas excess sugars and nitrogen starvation reduced its level; thus this pathway appears to fulfill multiple functions in stress-related and carbon/nitrogen metabolism. Carbon 227-233 lysine-ketoglutarate reductase/saccharopine dehydrogenase bifunctional enzyme Arabidopsis thaliana 13-20 12937175-5 2003 FATP1 exhibited similar substrate specificity for fatty acids 16-24 carbons in length, whereas ACS1 was 10-fold more active on long chain fatty acids relative to very long chain fatty acids. Carbon 68-75 solute carrier family 27 (fatty acid transporter), member 1 Mus musculus 0-5 14500500-3 2003 Recent progress has demonstrated the potential of quorum-sensing molecules, especially 3-oxo-C(12)-HSL, for modulation of the host immune system. Carbon 92-94 lipase E, hormone sensitive type Homo sapiens 99-102 14577615-1 2003 Methylenetetrahydrofolate reductase (MTHFR) reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, the major carbon donor in the remethylation of homocysteine to methionine. Carbon 122-128 methylenetetrahydrofolate reductase Homo sapiens 0-35 14577615-1 2003 Methylenetetrahydrofolate reductase (MTHFR) reduces 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, the major carbon donor in the remethylation of homocysteine to methionine. Carbon 122-128 methylenetetrahydrofolate reductase Homo sapiens 37-42 14499533-10 2003 The AAPBe concentrations are linearly correlated with the concentrations of suspended sediment, particulate organic carbon, particulate nitrogen, particulate phosphorus, and the AAP for several transition metals (Al, Co, Cr, Fe, Mn, Ni and Y), and the lanthanides. Carbon 116-122 serpin family F member 2 Homo sapiens 4-7 12967318-2 2003 The recently developed asymmetric silane alcoholysis and tandem silylformylation-crotylsilylation reactions were used as the key steps to establish the C(23)-C(27) 1,5-syn-diol. Carbon 152-153 synemin Homo sapiens 168-171 12917348-2 2003 We show for the IMD2 gene that this effect is not specific to certain carbon sources or to growth rate. Carbon 70-76 IMP dehydrogenase IMD2 Saccharomyces cerevisiae S288C 16-20 12953122-12 2003 However, the stimulation of AtNrt2.1 transcript accumulation by sucrose and glucose is abolished in an antisense AtHXK1 line, suggesting that HXK catalytic activity and carbon metabolism downstream of the HXK step are crucial for the sugar regulation of AtNrt2.1 expression. Carbon 169-175 hexokinase 1 Arabidopsis thaliana 113-119 14515459-2 2003 It is known that mutations in the PHO85 gene lead to constitutive synthesis of Pho5p acidic phosphatase, a delay in cell growth on media containing nonfermentable carbon sources, sensitivity to high temperature, and other phenotypic effects. Carbon 163-169 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 34-39 14515459-3 2003 A lack of growth at 37 degrees C and on a medium with alcohol as the carbon source was shown to be associated with the rapid accumulation of nuclear ts and mitochondrial [rho-] mutations occurring in the background of gene PHO85 inactivation. Carbon 69-75 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 223-228 21072616-1 2003 The relationship between carbon assimilation and high-level expression of the maize PEPC in PEPC transgenic rice was studied by comparison to that in the untransformed rice,japonica kitaake. Carbon 25-31 phosphoenolpyruvate carboxylase 1 Zea mays 84-88 21072616-6 2003 Treatment of the rice with the PEPC-specific inhibitor DCDP showed that overexpression of PEPC and enhancement of carbon assimilation were related to the stability of Fv/Fm. Carbon 114-120 phosphoenolpyruvate carboxylase 1 Zea mays 31-35 12748194-6 2003 Superimposed in the specific MhpR-mediated regulation of the Pa promoter, we have observed a strict catabolite repression control carried out by the cAMP receptor protein (CRP) that allows expression of the mhp catabolic genes when the preferred carbon source (glucose) is not available and 3HPP is present in the medium. Carbon 246-252 catabolite gene activator protein Escherichia coli 149-170 12748194-6 2003 Superimposed in the specific MhpR-mediated regulation of the Pa promoter, we have observed a strict catabolite repression control carried out by the cAMP receptor protein (CRP) that allows expression of the mhp catabolic genes when the preferred carbon source (glucose) is not available and 3HPP is present in the medium. Carbon 246-252 catabolite gene activator protein Escherichia coli 172-175 12676948-1 2003 ADR1 and CAT8 encode carbon source-responsive transcriptional regulators that cooperatively control expression of genes involved in ethanol utilization. Carbon 21-27 DNA-binding transcription factor ADR1 Saccharomyces cerevisiae S288C 0-4 12913293-6 2003 A five-carbon chain and hydroxamic acid, essential for histone deacetylase inhibition, were indispensable for this effect, and trichostatin A stimulated glucose uptake as well. Carbon 7-13 histone deacetylase 9 Homo sapiens 55-74 12816431-0 2003 Functionalization at C-12 of 1alpha,25-dihydroxyvitamin D(3) strongly modulates the affinity for the vitamin D receptor (VDR). Carbon 21-22 vitamin D receptor Homo sapiens 101-119 12816431-0 2003 Functionalization at C-12 of 1alpha,25-dihydroxyvitamin D(3) strongly modulates the affinity for the vitamin D receptor (VDR). Carbon 21-22 vitamin D receptor Homo sapiens 121-124 12739977-4 2003 The significance of the ligands is that by placing a ligating side chain on a ring carbon (C-3), rather than on a ring nitrogen, the ring nitrogen not bound to the metal and its attached proton are available for hydrogen bonding. Carbon 83-89 complement C3 Homo sapiens 91-94 12713312-3 2003 Spin delocalization on the nitro group is proposed to explain the stability of the carbon-centered radical generated. Carbon 83-89 spindlin 1 Homo sapiens 0-4 12590568-9 2003 These findings, together with the recent demonstration that C-H activation in PHM is dominated by quantum mechanical tunneling [Francisco et al. Carbon 60-61 peptidylglycine alpha-amidating monooxygenase Homo sapiens 78-81 12507833-4 2003 A marked increase in the propensity of FA-modified CG 117-136 to form an alpha-helix structure was observed for the C-8, C-10 and C-12 derivatives compared with unmodified/short-chain and long-chain (C-14, C-16, C-18) derivatives. Carbon 51-52 chromosome 12 open reading frame 57 Homo sapiens 121-125 12669822-3 2003 The VLCPUFA predominating in these lipids were a series of n-6 pentaenes and tetraenes with 24 to 32 carbons, including small amounts of odd-chain PUFA, 28:5n-6 and 24:5n-6 prevailing in CE and TG, respectively. Carbon 101-108 pumilio RNA binding family member 3 Homo sapiens 7-11 12467423-6 2002 These compounds are reasonably formed by dehydration of unisolated intermediate products 7 and/or 8 obtained by coupling of two molecules through a linkage between the C-2 and the C-3" carbons. Carbon 185-192 complement C3 Homo sapiens 180-183 12453860-1 2002 BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, a common mutation of the gene encoding the enzyme that catalyzes reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a carbon donor in the metabolism of folate, determines a striking reduction in the enzyme activity in carriers of mutation at homozygous status. Carbon 216-222 methylenetetrahydrofolate reductase Homo sapiens 12-47 12453860-1 2002 BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, a common mutation of the gene encoding the enzyme that catalyzes reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a carbon donor in the metabolism of folate, determines a striking reduction in the enzyme activity in carriers of mutation at homozygous status. Carbon 216-222 methylenetetrahydrofolate reductase Homo sapiens 49-54 12524347-3 2002 The organization of nucleosomes over the entire HIS-C region is altered in Su(var)3-9 mutants and there is a concomitant increase in expression of the histone genes. Carbon 52-53 Suppressor of variegation 3-9 Drosophila melanogaster 75-85 12528474-4 2002 Although C-24 position hydroxylation catalyzed by Cyp24 inactivates calcitriol, falecarcitriol is metabolized to C-23S hydroxylated metabolite by the same enzyme Cyp24 and this metabolite still has strong activity. Carbon 9-10 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 50-55 12401074-7 2002 The calculated values for the torsional angle around the S-O bond (delta(C-S-O-C)) of the syn-syn form are smaller than 80 degrees (72-78 degrees). Carbon 73-74 synemin Homo sapiens 90-93 12401074-7 2002 The calculated values for the torsional angle around the S-O bond (delta(C-S-O-C)) of the syn-syn form are smaller than 80 degrees (72-78 degrees). Carbon 73-74 synemin Homo sapiens 94-97 12226529-2 2002 Arabidopsis CYP90B1/DWF4 and CYP90A1/CPD are responsible for respective C-22 and C-23 hydroxylation of the steroid side chain and CYP85A1 catalyzes C-6 oxidation of 6-deoxo intermediates, whereas the functions of CYP90C1/ROT3, CYP90D1, and CYP85A2 are still unknown. Carbon 12-13 Cytochrome P450 superfamily protein Arabidopsis thaliana 20-24 12226529-2 2002 Arabidopsis CYP90B1/DWF4 and CYP90A1/CPD are responsible for respective C-22 and C-23 hydroxylation of the steroid side chain and CYP85A1 catalyzes C-6 oxidation of 6-deoxo intermediates, whereas the functions of CYP90C1/ROT3, CYP90D1, and CYP85A2 are still unknown. Carbon 12-13 cytochrome P450, family 90, subfamily D, polypeptide 1 Arabidopsis thaliana 227-234 12226529-2 2002 Arabidopsis CYP90B1/DWF4 and CYP90A1/CPD are responsible for respective C-22 and C-23 hydroxylation of the steroid side chain and CYP85A1 catalyzes C-6 oxidation of 6-deoxo intermediates, whereas the functions of CYP90C1/ROT3, CYP90D1, and CYP85A2 are still unknown. Carbon 29-30 cytochrome P450, family 90, subfamily D, polypeptide 1 Arabidopsis thaliana 227-234 12166938-1 2002 Endocannabinoid stucture-activity relationships (SAR) indicate that the CB1 receptor recognizes ethanolamides whose fatty acid acyl chains have 20 or 22 carbons, with at least three homoallylic double bonds and saturation in at least the last five carbons of the acyl chain. Carbon 153-160 sarcosine dehydrogenase Homo sapiens 49-52 12166938-1 2002 Endocannabinoid stucture-activity relationships (SAR) indicate that the CB1 receptor recognizes ethanolamides whose fatty acid acyl chains have 20 or 22 carbons, with at least three homoallylic double bonds and saturation in at least the last five carbons of the acyl chain. Carbon 248-255 sarcosine dehydrogenase Homo sapiens 49-52 12163697-6 2002 Recently, an interaction was observed between folate status and a common mutation in the gene encoding for methylenetetrahydrofolate reductase, an essential enzyme in one-carbon metabolism, in determining genomic DNA methylation. Carbon 171-177 methylenetetrahydrofolate reductase Homo sapiens 107-142 12371743-1 2002 In mammalian cells, Sprecher has proposed that the synthesis of long-chain PUFA from the 20-carbon substrates involves two consecutive elongation steps, a delta6-desaturation step followed by retroconversion (Sprecher, H., Biochim. Carbon 92-98 pumilio RNA binding family member 3 Homo sapiens 75-79 12371743-8 2002 Expression of these open reading frames in baker"s yeast, Saccharomyces cerevisiae, demonstrated that the encoded proteins were involved in the elongation of both 20- and 22-carbon long-chain PUFA, as determined by the conversion of 20:4n-6 to 22:4n-6, 22:4n-6 to 24:4n-6, 20:5n-3 to 22:5n-3, and 22:5n-3 to 24:5n-3. Carbon 174-180 pumilio RNA binding family member 3 Homo sapiens 192-196 12371743-9 2002 The elongation activity of the mouse Elovl2 was further demonstrated in the transformed mouse L cells incubated with long-chain (C20- and C22-carbon) n-6 and n-3 PUFA substrates by the significant increase in the levels of 24:4n-6 and 24:5n-3, respectively. Carbon 142-148 Sp7 transcription factor 7 Mus musculus 138-141 12125049-2 2002 The Hap4p subunit is the activator subunit and at the same time also the regulatory part of the complex, since it is the only one whose level is regulated by carbon source itself. Carbon 158-164 transcription factor HAP4 Saccharomyces cerevisiae S288C 4-9 12125049-5 2002 Carbon source-dependent activation mediated by the 265 bp fragment, as well as protein binding to the 30 nt CSRE-like region, is dependent on the presence of CAT8 function, unveiling a complex framework by which the expression of the HAP4 gene is coordinated. Carbon 0-6 transcription factor HAP4 Saccharomyces cerevisiae S288C 234-238 12126417-4 2002 Protonation on nitrogen leads to nucleophilic attack at the C-3 carbon and yields C-3 products. Carbon 64-70 complement C3 Homo sapiens 60-63 12126417-4 2002 Protonation on nitrogen leads to nucleophilic attack at the C-3 carbon and yields C-3 products. Carbon 64-70 complement C3 Homo sapiens 82-85 12503158-4 2002 The rearrangement that creates the iso-oxophlorin macrocycle 3 (4) results in near tetrahedral geometry around the C(15) (C(10)) carbon atom, with the C(14)-C(15) and C(15)-C(16) (C(9)-C(10) and C(10)-C(11)) bond lengths corresponding to a single C-C bond. Carbon 129-135 placenta associated 8 Homo sapiens 115-120 12244711-5 2002 A connection was established between the structure and kinetic characteristics of malate dehydrogenase--an enzyme of the TCA and glyoxylate cycles--and the type of carbon metabolism in the strains studied. Carbon 164-170 malic enzyme 1 Homo sapiens 82-102 12123456-4 2002 Mutations in the PGI1 and GND1 genes encoding carbon source utilization enzymes confer enhanced invasive growth that is unaffected by glucose but requires active Snf1. Carbon 46-52 glucose-6-phosphate isomerase Saccharomyces cerevisiae S288C 17-21 12123456-4 2002 Mutations in the PGI1 and GND1 genes encoding carbon source utilization enzymes confer enhanced invasive growth that is unaffected by glucose but requires active Snf1. Carbon 46-52 phosphogluconate dehydrogenase (decarboxylating) GND1 Saccharomyces cerevisiae S288C 26-30 12076159-4 2002 The lowest D values have been found for the hydrazonyl-substituted derivatives, which implies the lowest spin density at the carbon center and, thus, the most efficacious radical stabilization through spin delocalization. Carbon 125-131 spindlin 1 Homo sapiens 105-109 12076159-4 2002 The lowest D values have been found for the hydrazonyl-substituted derivatives, which implies the lowest spin density at the carbon center and, thus, the most efficacious radical stabilization through spin delocalization. Carbon 125-131 spindlin 1 Homo sapiens 201-205 12005586-0 2002 Spin-orbit coupling and electron spin resonance theory for carbon nanotubes. Carbon 59-65 spindlin 1 Homo sapiens 33-37 11943188-5 2002 We also showed that the mitochondrially activated PDR3 response is highly sensitive to both yeast strain variations and carbon sources. Carbon 120-126 drug-responsive transcription factor PDR3 Saccharomyces cerevisiae S288C 50-54 11890767-0 2002 An experimental test of C-N bond twisting in the TICT state: syn-anti photoisomerization in 2-(N-methyl-N-isopropylamino)-5-cyanopyridine. Carbon 24-25 synemin Homo sapiens 61-64 12702322-2 2002 In previous studies we have found that the genes encoding the unique components of this complex (GCV1, GCV2 and GCV3) are regulated by the one-carbon status of the cell. Carbon 143-149 glycine decarboxylase subunit H Saccharomyces cerevisiae S288C 112-116 11852246-2 2002 The responses mediated by Pho85 include cell-cycle progression and metabolism of nutrients such as phosphate and carbon sources. Carbon 113-119 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 26-31 11756540-6 2002 Chromatin immunoprecipitations show that Mcm1 binds in vivo to ECB elements throughout the cell cycle and that binding is sensitive to carbon source changes. Carbon 135-141 serum response factor Homo sapiens 41-45 11738932-6 2001 Inhibition of alpha-ketoglutarate dehydrogenase was evident at 25 min, as shown by accumulation of [(14)C]glutamate. Carbon 103-105 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) Mus musculus 14-47 11689080-3 2001 These azabicyclo[3.2.1] (bridged piperidine) series of compounds differ from the well-known benztropines by a 2-carbon spacer between C-3 and a diarylmethoxy moiety. Carbon 112-118 complement C3 Homo sapiens 134-137 11574020-2 2001 This study indicates that an initial concerted [4 + 2] cycloaddition followed by a stereospecific carbon-selenium bond oxidation is involved in this unprecedented syn dihydroxy addition reaction mediated by selenium dioxide. Carbon 98-104 synemin Homo sapiens 163-166 18968360-0 2001 Detection of phenolic compounds in flow systems based on tyrosinase-modified reticulated vitreous carbon electrodes. Carbon 98-104 tyrosinase Homo sapiens 57-67 18968360-1 2001 The fabrication and performance of a reticulated vitreous carbon (RVC)-based tyrosinase flow-through electrode, in which the enzyme was covalently immobilized, is reported. Carbon 58-64 tyrosinase Homo sapiens 77-87 11511175-5 2001 The molecular ions and fragmentation of the dGuo, dAdo, and dCyd adducts were consistent with nucleophilic addition of the exocyclic primary amine of the nucleosides to the methylene carbon of 3-methyleneindolenine. Carbon 183-189 ado Drosophila melanogaster 50-54 11453702-6 2001 The purA and sorC mutants were deficient in their ability to grow in defined minimal media, without adenine, and with sorbose as sole carbon source, respectively, yet capable of normal growth in complex media. Carbon 134-140 purine rich element binding protein A Homo sapiens 4-8 11371572-6 2001 The inhibition of methionine synthase activity disrupted carbon flow through the folate pathway as measured by decreased incorporation of [(14)C]formate into methionine, serine, and purine nucleotides. Carbon 57-63 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens 18-37 11470433-1 2001 BACKGROUND: The crystal structure of precorrin-8x methyl mutase (CobH), an enzyme of the aerobic pathway to vitamin B12, provides evidence that the mechanism for methyl migration can plausibly be regarded as an allowed [1,5]-sigmatropic shift of a methyl group from C-11 to C-12 at the C ring of precorrin-8x to afford hydrogenobyrinic acid. Carbon 2-3 RNA polymerase III subunit K Homo sapiens 266-270 11394791-2 2001 Tap water, which had been filtered through biologically active granular activated carbon, was used as an innoculum for biofilm growth in annular reactors (ARs). Carbon 82-88 nuclear RNA export factor 1 Homo sapiens 0-3 11372865-0 2001 Effects of oxygen on formation of PCB and PCDD/F on extracted fly ash in the presence of carbon and cupric salt. Carbon 89-95 Pyruvate carboxylase Drosophila melanogaster 34-37 11180457-2 2001 Ten cyclin-like proteins are known to interact with Pho85, and combination with different cyclins is believed to be responsible for distinct Pho85 functions, including phosphate metabolism, carbon source utilization and cell cycle regulation. Carbon 190-196 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 52-57 11180457-2 2001 Ten cyclin-like proteins are known to interact with Pho85, and combination with different cyclins is believed to be responsible for distinct Pho85 functions, including phosphate metabolism, carbon source utilization and cell cycle regulation. Carbon 190-196 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 141-146 11180457-5 2001 We found that expression of various genes involved in carbon metabolism are affected by the mutation and that among them, UGP1 promoter activity was increased in the absence of Pho85 kinase. Carbon 54-60 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 177-182 11180457-7 2001 We also found that expression of several Pho85-cyclin genes were altered by the carbon source, the growth phase and Pho85 kinase itself. Carbon 80-86 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 41-46 11133279-1 2001 A general and very simple strategy for achieving clean spin-state-selective excitation with full sensitivity in carbon-selective gradient-enhanced 1D HMQC and HSQC pulse schemes is presented. Carbon 112-118 spindlin 1 Homo sapiens 55-59 11133279-5 2001 Such an approach affords a suite of powerful selective 1D (13)C-edited NMR experiments which are helpful for resonance assignment purposes in overcrowded proton spin systems and also for the accurate determination of the magnitude and sign of long-range proton-carbon coupling constants in CH spin sytems for samples at natural abundance. Carbon 261-267 spindlin 1 Homo sapiens 161-165 11133279-5 2001 Such an approach affords a suite of powerful selective 1D (13)C-edited NMR experiments which are helpful for resonance assignment purposes in overcrowded proton spin systems and also for the accurate determination of the magnitude and sign of long-range proton-carbon coupling constants in CH spin sytems for samples at natural abundance. Carbon 261-267 spindlin 1 Homo sapiens 293-297 11468972-1 2001 Methylenetetrahydrofolate reductase (MTHFR), is a cytosolic enzyme, the product of which is N5-metyltetrahydrofolate, the main form of folates in tissues and the carbon donor for methylation of homocysteine to methionine. Carbon 162-168 methylenetetrahydrofolate reductase Homo sapiens 0-35 11468972-1 2001 Methylenetetrahydrofolate reductase (MTHFR), is a cytosolic enzyme, the product of which is N5-metyltetrahydrofolate, the main form of folates in tissues and the carbon donor for methylation of homocysteine to methionine. Carbon 162-168 methylenetetrahydrofolate reductase Homo sapiens 37-42 11695477-1 2001 Iodized X-ray contrast media (XRC) for medical applications are responsible for the high concentration of AOX (halogenated organic compounds adsorbable on activated carbon) in hospital wastewater exceeding the legal German discharge limit. Carbon 165-171 acyl-CoA oxidase 1 Homo sapiens 106-109 11149860-2 2000 The observed syn selectivities and re-face attack of silyl enol ethers on carbonyl carbon of aldehydes imply that the extended-transition state model is applicable. Carbon 74-80 synemin Homo sapiens 13-16 11104700-0 2000 A carbon-source-responsive element is required for regulation of the hypoxic ADP/ATP carrier (AAC3) isoform in Saccharomyces cerevisiae. Carbon 2-8 ADP/ATP carrier protein AAC3 Saccharomyces cerevisiae S288C 94-98 11104700-3 2000 By deletion analysis, DNA electrophoretic mobility-shift assays, DNase I footprinting and site-directed mutagenesis, we have identified a promoter region (upstream repressing sequence 1, URS(1)) involved in a carbon-source-dependent repression of AAC3. Carbon 209-215 ADP/ATP carrier protein AAC3 Saccharomyces cerevisiae S288C 247-251 11104700-6 2000 These findings demonstrate that the hypoxic AAC3 gene is regulated by two upstream repressor sites; one controlled by oxygen and haem, the other by the carbon source. Carbon 152-158 ADP/ATP carrier protein AAC3 Saccharomyces cerevisiae S288C 44-48 11086724-2 2000 Specifically, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one, the t-CFA containing 15 carbon atoms on the side chain (t-CFA n = 15) stimulated arginine vasopressin secretion in nerve terminals of the neurohypophysis. Carbon 99-105 tubulin folding cofactor A Homo sapiens 81-84 10992236-10 2000 Bis(Args) analogs of 8, 10 and 12 carbon atoms using 1,3-diaminopropane and 1, 3-diamino-2-hydroxy-propane as hydrocarbon spacers were prepared at the 6-7 gram level employing the methodology developed. Carbon 34-40 serpin family A member 2 (gene/pseudogene) Homo sapiens 4-8 11080594-1 2000 Methylenetetrahydrofolate reductase (MTHFR), a pivotal enzyme in folate metabolism, regulates the proportional distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis. Carbon 131-137 methylenetetrahydrofolate reductase Homo sapiens 0-35 11080594-1 2000 Methylenetetrahydrofolate reductase (MTHFR), a pivotal enzyme in folate metabolism, regulates the proportional distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis. Carbon 131-137 methylenetetrahydrofolate reductase Homo sapiens 37-42 11052089-3 2000 The absolute configuration of the newly formed carbon-carbon bond is primarily controlled by the chiral sulfur atom, which in a nonreinforcing situation can override the intrinsic anti tendency of the vinyl oxirane moiety and forces the cuprate to undergo syn addition. Carbon 47-53 synemin Homo sapiens 256-259 11052089-3 2000 The absolute configuration of the newly formed carbon-carbon bond is primarily controlled by the chiral sulfur atom, which in a nonreinforcing situation can override the intrinsic anti tendency of the vinyl oxirane moiety and forces the cuprate to undergo syn addition. Carbon 54-60 synemin Homo sapiens 256-259 11028635-1 2000 A novel tyrosinase biosensor has been developed for the subnanomolar detection of phenols, based on the immobilization of tyrosinase in a positively charged Al2O3 sol-gel membrane on a glassy carbon electrode. Carbon 192-198 tyrosinase Homo sapiens 8-18 11069666-1 2000 Saccharomyces cerevisiae strains lacking a functional Pho85 cyclin-dependent kinase (cdk) exhibit a complex phenotype, including deregulation of phosphatase genes controlled by the transcription factor Pho4, slow growth on rich media, failure to grow using galactose, lactate or glycerol as a carbon source and hyperaccumulation of glycogen. Carbon 293-299 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 54-59 10944191-6 2000 PS2 shows only a single broad and intense emissive signal, which is assigned to both the C-10 and C-15 methine carbon atoms. Carbon 111-117 placenta associated 8 Homo sapiens 98-102 10924114-1 2000 Adenosylcobalamin-dependent methylmalonyl-CoA mutase catalyzes the interconversion of methylmalonyl-CoA and succinyl-CoA via radical intermediates generated by substrate-induced homolysis of the coenzyme carbon-cobalt bond. Carbon 204-210 methylmalonyl-CoA mutase Homo sapiens 28-52 10991284-0 2000 Spin configurations of a carbon nanotube in a nonuniform external potential We study, theoretically, the ground state spin of a carbon nanotube in the presence of an external potential. Carbon 25-31 spindlin 1 Homo sapiens 0-4 10991284-0 2000 Spin configurations of a carbon nanotube in a nonuniform external potential We study, theoretically, the ground state spin of a carbon nanotube in the presence of an external potential. Carbon 25-31 spindlin 1 Homo sapiens 118-122 10991284-0 2000 Spin configurations of a carbon nanotube in a nonuniform external potential We study, theoretically, the ground state spin of a carbon nanotube in the presence of an external potential. Carbon 128-134 spindlin 1 Homo sapiens 0-4 10991284-0 2000 Spin configurations of a carbon nanotube in a nonuniform external potential We study, theoretically, the ground state spin of a carbon nanotube in the presence of an external potential. Carbon 128-134 spindlin 1 Homo sapiens 118-122 10825197-0 2000 Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress. Carbon 82-88 Aca1p Saccharomyces cerevisiae S288C 0-4 10825197-0 2000 Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress. Carbon 82-88 Cst6p Saccharomyces cerevisiae S288C 9-13 10825197-4 2000 Aca2 is important for a variety of biological functions including growth on nonoptimal carbon sources, and Aca2-dependent activation is modestly regulated by carbon source. Carbon 87-93 Cst6p Saccharomyces cerevisiae S288C 0-4 10825197-4 2000 Aca2 is important for a variety of biological functions including growth on nonoptimal carbon sources, and Aca2-dependent activation is modestly regulated by carbon source. Carbon 87-93 Cst6p Saccharomyces cerevisiae S288C 107-111 10825197-4 2000 Aca2 is important for a variety of biological functions including growth on nonoptimal carbon sources, and Aca2-dependent activation is modestly regulated by carbon source. Carbon 158-164 Cst6p Saccharomyces cerevisiae S288C 0-4 10825197-4 2000 Aca2 is important for a variety of biological functions including growth on nonoptimal carbon sources, and Aca2-dependent activation is modestly regulated by carbon source. Carbon 158-164 Cst6p Saccharomyces cerevisiae S288C 107-111 10832082-1 2000 The potential of the (11)C-labeled selective sigma(1) receptor ligand 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine ([(11)C]SA4503) was evaluated in vivo as a positron emission tomography (PET) ligand for mapping sigma(1) receptors in rats. Carbon 25-26 sigma non-opioid intracellular receptor 1 Rattus norvegicus 45-62 10813946-3 2000 Syn-adducts have been obtained in all cases as the major isomers, independently of the Z/E stereochemistry of the double bond and the number and the nature of the substituents, the chirality of the asymmetric allylic carbon being the only thing responsible for the diastereoselection. Carbon 217-223 synemin Homo sapiens 0-3 11040520-0 2000 Spectroscopy of excited states of carbon anions above the photodetachment threshold Electronic transitions of C3- and C5- to states lying above the electron affinity of the neutral (EA) have been recorded in the gas phase by laser photodetachment spectroscopy. Carbon 34-40 complement C3 Homo sapiens 110-120 10564066-6 1999 Compounds with 9-11 carbons at C-3 and 6-10 carbons at C-2 provided good separation (up to 2.7-fold) between activity and cytotoxicity. Carbon 20-27 complement C3 Homo sapiens 31-34 10490916-7 1999 The mass spectra of the two minor NAC adducts indicated that they were the two diastereomers in which NAC was attached to the exo-cyclic prechiral carbon of the pyrimidine iminoquinone methide. Carbon 147-153 X-linked Kx blood group Homo sapiens 34-37 10490916-7 1999 The mass spectra of the two minor NAC adducts indicated that they were the two diastereomers in which NAC was attached to the exo-cyclic prechiral carbon of the pyrimidine iminoquinone methide. Carbon 147-153 X-linked Kx blood group Homo sapiens 102-105 10468640-7 1999 More importantly, our results also suggest that the 3" untranslated region of the Incw1 gene acts as a regulatory sensor of carbon starvation and may constitute a link between sink metabolism and cellular translation in plants. Carbon 124-130 beta-fructofuranosidase, cell wall isozyme Zea mays 82-87 10364640-9 1999 Thus, not only MTHFR but also APOE appears to be related to the one-carbon metabolism, suggesting that APOE4 and insufficient one-carbon metabolism may be synergistic risk factors for AD. Carbon 68-74 methylenetetrahydrofolate reductase Homo sapiens 15-20 10383958-3 1999 The specific activities of three enzymes, an alpha-glucosidase (malA), a beta-glycosidase (lacS), and an alpha-amylase, were reduced 4-, 20-, and 10-fold, respectively, in response to the addition of supplementary carbon sources to a minimal sucrose medium. Carbon 214-220 ABC transporter permease Saccharolobus solfataricus 45-62 10371437-1 1999 Resolved localized nuclear magnetic resonance (NMR) signals of 1H bound to 13C label in the carbon positions of glutamate C4, C3 and glutamine C4, C3, as well as in aspartate C3, lactate C3, alanine C3, gamma-aminobutyric acid C3, and glucose C1 were simultaneously observed in spectra obtained from rat brain in vivo. Carbon 92-98 complement C3 Rattus norvegicus 126-149 11674459-4 1999 On catalytic hydrogenation of the tetrachlorooxabicyclooctenones 3a-c hydrogenolysis of the exo-carbon-chlorine bonds occurs, leading to the endo-2,endo-4-dichloro-8-oxabicyclooctan-3-ones 8a-c. With lithium aluminum hydride and Grignard reagents, 8a and 3a form the endo-3-alcohols 12a-c and 13, respectively, the latter with uncertain configuration at C-3, in a highly stereoselective manner. Carbon 96-102 complement C3 Homo sapiens 354-357 10066930-17 1999 Flash photolysis of caged InsP3 (20 microM) evoked reproducible increases in [Ca2+]c. CCCP (5 microM) reduced the magnitude of the [Ca2+]c transients evoked by flash photolysis of caged InsP3. Carbon 20-21 LOW QUALITY PROTEIN: carbonic anhydrase 2 Cavia porcellus 78-81 10066930-17 1999 Flash photolysis of caged InsP3 (20 microM) evoked reproducible increases in [Ca2+]c. CCCP (5 microM) reduced the magnitude of the [Ca2+]c transients evoked by flash photolysis of caged InsP3. Carbon 20-21 LOW QUALITY PROTEIN: carbonic anhydrase 2 Cavia porcellus 132-135 10075811-0 1999 Mediated, amperometric biosensor for glucose-6-phosphate monitoring based on entrapped glucose-6-phosphate dehydrogenase, Mg2+ ions, tetracyanoquinodimethane, and nicotinamide adenine dinucleotide phosphate in carbon paste. Carbon 210-216 glucose-6-phosphate dehydrogenase Homo sapiens 87-120 11670859-1 1999 This paper reports the syntheses, characterization, and structures of two new two-dimensional cadmium-thiocyanate coordination solids [(12C4)(2)Cd][Cd(2)(SCN)(6)] (1) and [(12C4)(2)Cd][Cd(3)(SCN)(8)] (2), where 12C4 denotes 12-crown-4, C(8)H(16)O(4). Carbon 138-139 sorcin Homo sapiens 154-157 10420575-2 1999 Infrared and solid state NMR 13C analysis of MA and the ligand strongly suggests that antimony binds to N-methyl glucamine through the oxygen of C-3 carbon. Carbon 149-155 complement C3 Homo sapiens 145-148 10096087-3 1999 The same protein is also the regulatory part of the complex in response to carbon sources, as HAP4 is strongly induced during the shift from fermentative to respiratory metabolism in S. cerevisiae. Carbon 75-81 transcription factor HAP4 Saccharomyces cerevisiae S288C 94-98 10448518-5 1999 The widely studied one-carbon, reduced-folate transport system is mediated by a transporter encoded by the newly discovered RFC-1 (reduced-folate carrier) gene. Carbon 23-29 replication factor C subunit 1 Homo sapiens 124-154 9813046-2 1998 A mutant devoid of Eci1p was unable to grow on media containing unsaturated fatty acids such as oleic acid but was proficient for growth when a saturated fatty acid such as palmitic acid was the sole carbon source. Carbon 200-206 dodecenoyl-CoA isomerase Saccharomyces cerevisiae S288C 19-24 29711127-3 1998 The new stereostructure was confirmed by the total synthesis, which involves stereoselective access to the pyrroloindoline syn-cis-1 and the 5-hydroxypiperazic acid subunit and features a Stille coupling for the formation of the central carbon-carbon bond. Carbon 237-243 synemin Homo sapiens 51-54 29711127-3 1998 The new stereostructure was confirmed by the total synthesis, which involves stereoselective access to the pyrroloindoline syn-cis-1 and the 5-hydroxypiperazic acid subunit and features a Stille coupling for the formation of the central carbon-carbon bond. Carbon 244-250 synemin Homo sapiens 51-54 29711142-3 1998 The new stereostructure was confirmed by the total synthesis, which involves stereoselective access to the pyrroloindoline syn-cis-1 and the 5-hydroxypiperazic acid subunit and features a Stille coupling for the formation of the central carbon-carbon bond. Carbon 237-243 synemin Homo sapiens 51-54 29711142-3 1998 The new stereostructure was confirmed by the total synthesis, which involves stereoselective access to the pyrroloindoline syn-cis-1 and the 5-hydroxypiperazic acid subunit and features a Stille coupling for the formation of the central carbon-carbon bond. Carbon 244-250 synemin Homo sapiens 51-54 9873670-0 1998 Derivatization of the C12-C13 functional groups of epothilones A, B and C. Carbon 22-23 homeobox C13 Homo sapiens 26-29 9789068-1 1998 A common mutation (C677T) in the gene encoding for methylenetetrahydrofolate reductase (MTHFR) (5-methyltetrahydrofolate:(acceptor) oxidoreductase, EC 1.7.99.5), a key regulatory enzyme in one-carbon metabolism, results in a thermolabile variant of the MTHFR enzyme with reduced activity in vitro. Carbon 193-199 methylenetetrahydrofolate reductase Homo sapiens 51-86 9789068-1 1998 A common mutation (C677T) in the gene encoding for methylenetetrahydrofolate reductase (MTHFR) (5-methyltetrahydrofolate:(acceptor) oxidoreductase, EC 1.7.99.5), a key regulatory enzyme in one-carbon metabolism, results in a thermolabile variant of the MTHFR enzyme with reduced activity in vitro. Carbon 193-199 methylenetetrahydrofolate reductase Homo sapiens 88-93 9789068-1 1998 A common mutation (C677T) in the gene encoding for methylenetetrahydrofolate reductase (MTHFR) (5-methyltetrahydrofolate:(acceptor) oxidoreductase, EC 1.7.99.5), a key regulatory enzyme in one-carbon metabolism, results in a thermolabile variant of the MTHFR enzyme with reduced activity in vitro. Carbon 193-199 thioredoxin reductase 1 Homo sapiens 132-146 9753737-6 1998 However, two longer SIR1 transcripts were regulated reciprocally by carbon source. Carbon 68-74 Sir1p Saccharomyces cerevisiae S288C 20-24 9742088-9 1998 Disruption of YHM2 causes a significant growth defect in the presence of nonfermentable carbon sources such as glycerol and ethanol, and the cells have defects in respiration as determined by 2,3,5,-triphenyltetrazolium chloride staining. Carbon 88-94 Yhm2p Saccharomyces cerevisiae S288C 14-18 9687543-5 1998 When hepatocytes were incubated with 1 mmol/L FA, the LCAT secretion increased 50-100% (P < 0.01) in the presence of the 18-carbon FA (stearic, oleic, elaidic and linoleic acids), whereas the presence of butyric, lauric and palmitic acids had no significant effect. Carbon 127-133 lecithin cholesterol acyltransferase Rattus norvegicus 54-58 9618482-1 1998 Abf2p is a high mobility group (HMG) protein found in yeast mitochondria that is required for the maintenance of wild-type (rho+) mtDNA in cells grown on fermentable carbon sources, and for efficient recombination of mtDNA markers in crosses. Carbon 166-172 DNA-binding protein ABF2 Saccharomyces cerevisiae S288C 0-5 9563974-1 1998 The reaction of lysyl oxidase was assessed with members of a series of aminoalkylaziridines in which the primary amino group and the aziridinyl nitrogen were separated by 3-7 methylene carbons. Carbon 185-192 lysyl oxidase Homo sapiens 16-29 9512480-2 1998 Phosphoenolpyruvate carboxylase (PEPC) is a key enzyme in the supply of carbon skeletons for the assimilation of nitrogen by green algae. Carbon 72-78 uncharacterized protein Chlamydomonas reinhardtii 0-31 9535221-4 1998 This is the first evidence of 15-PGDH converting a substrate hydroxyl group at a position other than the omega-6 carbon. Carbon 113-119 carbonyl reductase 1 Homo sapiens 30-37 9511473-3 1998 The enzymes salicylate hydroxylase and tyrosinase were coimmobilized first in a carbon paste electrode for the sensitive detection of NADH. Carbon 80-86 tyrosinase Homo sapiens 39-49 9511473-7 1998 Prior to adding PADH, the salicylate hydroxylase-tyrosinase carbon paste electrode was characterized in terms of its sensitivity to NADH, pH dependence, buffer composition, interferences, and stability. Carbon 60-66 tyrosinase Homo sapiens 49-59 9568282-1 1998 Two catalytic pathways have been proposed for the flavoenzyme monoamine oxidase B (MAO-B)--one based on an initial single electron transfer (SET) step from the nitrogen lone pair and the second based on an initial alpha-carbon hydrogen atom transfer (HAT) step. Carbon 220-226 monoamine oxidase B Homo sapiens 62-81 9568282-1 1998 Two catalytic pathways have been proposed for the flavoenzyme monoamine oxidase B (MAO-B)--one based on an initial single electron transfer (SET) step from the nitrogen lone pair and the second based on an initial alpha-carbon hydrogen atom transfer (HAT) step. Carbon 220-226 monoamine oxidase B Homo sapiens 83-88 9501134-0 1998 Expression of an arabidopsis aspartate Kinase/Homoserine dehydrogenase gene is metabolically regulated by photosynthesis-related signals but not by nitrogenous compounds Although the control of carbon fixation and nitrogen assimilation has been studied in detail, relatively little is known about the regulation of carbon and nitrogen flow into amino acids. Carbon 195-201 aspartate kinase-homoserine dehydrogenase ii Arabidopsis thaliana 29-70 9501134-0 1998 Expression of an arabidopsis aspartate Kinase/Homoserine dehydrogenase gene is metabolically regulated by photosynthesis-related signals but not by nitrogenous compounds Although the control of carbon fixation and nitrogen assimilation has been studied in detail, relatively little is known about the regulation of carbon and nitrogen flow into amino acids. Carbon 316-322 aspartate kinase-homoserine dehydrogenase ii Arabidopsis thaliana 29-70 9331084-2 1997 Mass spectra analysis of 13C-labeled carbons revealed that these PC reactions contribute to over 85% of de novo ribose synthesis in RNA from [1,2-(13)C]glucose in cultured Mia pancreatic adenocarcinoma cells, with the fraction synthesized through the TK pathway predominating (85%). Carbon 37-44 transketolase Mus musculus 251-253 9383192-5 1997 We suggest that regulation of ENA1 by the SNF1 pathway could be part of a general mechanism through which yeast cells respond to carbon source starvation by activating protective systems against different types of stress. Carbon 129-135 Na(+)/Li(+)-exporting P-type ATPase ENA1 Saccharomyces cerevisiae S288C 30-34 9286980-9 1997 Consistent with this finding and unlike the parent strain, the argR::Gm derivative was unable to utilize arginine or ornithine as the sole carbon source. Carbon 139-145 transcriptional regulator ArgR Pseudomonas aeruginosa PAO1 63-67 9261170-5 1997 When grown on either glucose or glycerol as a carbon source, a glo2 glo4 double deletion strain contains no glyoxalase II activity at all and shows no obvious phenotype during vegetative growth. Carbon 46-52 hydroxyacylglutathione hydrolase GLO2 Saccharomyces cerevisiae S288C 63-72 18966880-0 1997 Immobilization of uricase to gas diffusion carbon felt by electropolymerization of aniline and its application as an enzyme reactor for uric acid sensor. Carbon 43-49 urate oxidase (pseudogene) Homo sapiens 18-25 18966880-1 1997 Electropolymerizations of aniline and pyrrole solutions containing uricase at a neutral pH was performed to immobilize the enzyme on the surface of the gas diffusion carbon felt, and a selective uric acid sensor was fabricated by combining immobilized enzyme carbon felt and an oxygen electrode with oxygen gas permeable membrane. Carbon 166-172 urate oxidase (pseudogene) Homo sapiens 67-74 18966880-1 1997 Electropolymerizations of aniline and pyrrole solutions containing uricase at a neutral pH was performed to immobilize the enzyme on the surface of the gas diffusion carbon felt, and a selective uric acid sensor was fabricated by combining immobilized enzyme carbon felt and an oxygen electrode with oxygen gas permeable membrane. Carbon 259-265 urate oxidase (pseudogene) Homo sapiens 67-74 18966880-2 1997 This carbon felt has a desirable feature for uricase sensing because an extremely efficient supply of oxygen for the enzymatic reaction can be realized due to its porosity permitting a transfer of oxygen. Carbon 5-11 urate oxidase (pseudogene) Homo sapiens 45-52 9200687-2 1997 Spin-labeled biotin-PEs were prepared with the nitroxide group at position C-5, C-8, C-10, C-12, or C-14 of the sn-2 chain and were incorporated at 1 mol % in lipid bilayer membranes of dimyristoylphosphatidylcholine. Carbon 75-76 spindlin 1 Homo sapiens 0-4 9200687-2 1997 Spin-labeled biotin-PEs were prepared with the nitroxide group at position C-5, C-8, C-10, C-12, or C-14 of the sn-2 chain and were incorporated at 1 mol % in lipid bilayer membranes of dimyristoylphosphatidylcholine. Carbon 80-81 spindlin 1 Homo sapiens 0-4 9200812-8 1997 The alterations in the basal levels of expression of the high-affinity iron uptake genes may explain why the AFT1 mutant is unable to grow on respirable carbon sources. Carbon 153-159 DNA-binding transcription factor AFT1 Saccharomyces cerevisiae S288C 109-113 9133646-4 1997 The enzyme had an apparent subunit molecular weight of 54000, required NAD+ as cofactor, had optimal activity at pH 9.8, and was thermolabile at 47 degrees C. Fatty aldehyde dehydrogenase had high activity towards saturated and unsaturated aliphatic aldehydes ranging from 6 to 24 carbons in length, as well as dihydrophytal, a 20-carbon branched chain aldehyde. Carbon 281-288 aldehyde dehydrogenase 3 family member A2 Homo sapiens 159-187 9124555-11 1997 The fraction of recycled carbon and of the Cori cycle were elevated in the CAI group vs. the CAII and NL groups: 15 and 33% vs. 7.8 and 19%, respectively (P = 0.01). Carbon 25-31 carbonic anhydrase 2 Homo sapiens 93-97 9013574-1 1997 An important focus of structure-function studies of synthetic ligands for the vitamin D receptor (VDR) concerns the chiral center at carbon 20 of the steroid side chain; 20-epi analogues are 100-10, 000 times more potent transcriptionally than the natural hormone 1alpha,25-dihydroxyvitamin D3 (1alpha,25-(OH)2D3). Carbon 133-139 vitamin D receptor Homo sapiens 78-96 9013574-1 1997 An important focus of structure-function studies of synthetic ligands for the vitamin D receptor (VDR) concerns the chiral center at carbon 20 of the steroid side chain; 20-epi analogues are 100-10, 000 times more potent transcriptionally than the natural hormone 1alpha,25-dihydroxyvitamin D3 (1alpha,25-(OH)2D3). Carbon 133-139 vitamin D receptor Homo sapiens 98-101 9147137-6 1997 With insoluble elastin, elastolysis inhibition could be demonstrated for alkyl chain longer than ten carbon atoms, the effect increasing with chain length. Carbon 101-107 elastin Homo sapiens 15-22 9023182-3 1997 strain AT3 grew with dl-tropic acid, the aromatic component of the alkaloid atropine, as the sole source of carbon and energy. Carbon 108-114 ataxin 3 Homo sapiens 7-10 9008638-9 1997 With a nominally Ca(2+)-free solution containing 10 microM cyclopiazonic acid, simultaneous 10(-6) M ET-1 and extracellular Ca2+ additions transiently increased [Ca2+]i twofold, whereas 10(-6) M S-6-c increased it by only 20%. Carbon 195-200 endothelin 1 Bos taurus 101-105 9008638-12 1997 S-6-c (10(-6) M) increased the level of ET-1-LI after 12 hours by approximately ninefold. Carbon 0-5 endothelin 1 Bos taurus 40-44 8812911-7 1996 The pulse sequences are tested on the peptide hormone motilin with a selectively 13C-enriched alpha carbon. Carbon 100-106 motilin Homo sapiens 54-61 8818277-3 1996 Ethanol was used as the main carbon source to provoke GM-CSF expression. Carbon 29-35 colony stimulating factor 2 (granulocyte-macrophage) Mus musculus 54-60 8710512-3 1996 The multiple interactions of nuclear proteins with the UAS region of CYT1 observed in electrophoretic mobility shift experiments are influenced by carbon source and oxygen tension, but are independent of both regulators, Hap1p and Hap2/3/4/5. Carbon 147-153 ubiquinol--cytochrome-c reductase catalytic subunit CYT1 Saccharomyces cerevisiae S288C 69-73 8657561-6 1996 Gel mobility shift analysis and in vitro DNase I footprinting have shown that proteins bind specifically to two downstream repressor sequences (DRS1 located from +140 to +163 and DRS2 located between +231 and +251) that influence the rate of HXK2 transcription when ethanol is used as carbon source by Saccharomyces cerevisiae. Carbon 285-291 putative ATP-dependent RNA helicase Saccharomyces cerevisiae S288C 144-148 8722762-2 1996 We described several unique phenotypes associated with the deletion of the PHO85 gene including growth defects on a variety of carbon sources and hyperaccumulation of glycogen in rich medium high in Pi. Carbon 127-133 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 75-80 8549771-3 1995 The Saccharomyces cerevisiae Pas3p, a homologue of per9p, restored peroxisome biogenesis and peroxisomal protein import in the delta per9 mutant, allowing it to grow again on methanol as sole carbon and energy source. Carbon 192-198 ion-transporting P-type ATPase SPF1 Saccharomyces cerevisiae S288C 51-56 8549771-3 1995 The Saccharomyces cerevisiae Pas3p, a homologue of per9p, restored peroxisome biogenesis and peroxisomal protein import in the delta per9 mutant, allowing it to grow again on methanol as sole carbon and energy source. Carbon 192-198 ion-transporting P-type ATPase SPF1 Saccharomyces cerevisiae S288C 51-55 8748705-1 1995 Following the nomenclature of Sandberg, the W4 sequence of human elastin, [sequence: see text], has been synthesized by solid-phase methods and characterized by carbon-13 nuclear magnetic resonance, amino-acid analysis, mass spectra and elemental analysis. Carbon 161-167 elastin Homo sapiens 65-72 7593207-8 1995 Pretreatment of B16a cells with either calphostin C or genistein abolished 12(S)-HETE-increased formation of vinculin- and phosphotyrosine-containing focal adhesions. Carbon 50-51 vinculin Mus musculus 109-117 7562483-6 1995 The basolateral uptake of PAH and PCG were not affected by aliphatic dicarboxylates with 3 or 4 carbon atoms, but were strongly inhibited by those with 5 or 6 carbon atoms. Carbon 96-102 psoriasis susceptibility 1 candidate 2 Rattus norvegicus 34-37 7562483-6 1995 The basolateral uptake of PAH and PCG were not affected by aliphatic dicarboxylates with 3 or 4 carbon atoms, but were strongly inhibited by those with 5 or 6 carbon atoms. Carbon 159-165 psoriasis susceptibility 1 candidate 2 Rattus norvegicus 34-37 7544623-2 1995 The chemical shifts of C-13 labeled carbonyl carbons vs. CaCl2 concentration demonstrate that Ca2+ and Cl- ions interact as an ion pair within the GA structure with the Cl- ion located near the position of the carbonyl group of the Trp11 residue some 5.5 A from the mouth of the GA helix, and the Ca2+ ion bound at the position of the carbonyl group of the Trp15 residue some 2.5 A from the entrance to the helical pore. Carbon 45-52 homeobox C13 Homo sapiens 23-27 7548753-2 1995 This behavior led us to speculate that the pathway for the MAO-B catalyzed oxidation of these tetrahydropyridines may not necessarily proceed via an initial single electron transfer step as proposed by others but rather through an initial alpha-carbon hydrogen atom abstraction step. Carbon 245-251 monoamine oxidase B Homo sapiens 59-64 7760058-6 1995 From the C-3/C-4 labeling ratios in glutamine and glutamate and from the corresponding C-3/C-2 labeling ratio in GABA obtained with [2-13C]acetate, it was concluded that the carbon skeleton of glutamine to some extent was passed through TCA cycles before glutamate and GABA were formed. Carbon 174-180 complement component 2 (within H-2S) Mus musculus 91-94 7742328-6 1995 The syn glycosidic torsion angle at [AF]dG6 is supported by both carbon and proton chemical shift data for the sugar resonances of the modified guanine residue. Carbon 65-71 synemin Homo sapiens 4-7 18623311-4 1995 D-Lactate dehydrogenase, nicotinamide adenine dinucleotide (NAD(+)), a synthetic redox polymer containing covalently attached toluidine blue O as mediator, graphite powder, and paraffin oil were used for the construction of the modified carbon paste electrode. Carbon 237-243 lactate dehydrogenase D Homo sapiens 0-23 7669085-0 1995 Changes in elastin in human atherosclerotic aorta: carbon-13 magic angle sample-spinning NMR studies. Carbon 51-57 elastin Homo sapiens 11-18 7669085-6 1995 While alpha-carbons of human atherosclerotic elastin had shorter T1pC than normal elastin alpha carbons, carbons from hydrophobic amino acid side chains had longer T1pC for atherosclerotic then for normal elastin. Carbon 12-19 elastin Homo sapiens 45-52 7669085-6 1995 While alpha-carbons of human atherosclerotic elastin had shorter T1pC than normal elastin alpha carbons, carbons from hydrophobic amino acid side chains had longer T1pC for atherosclerotic then for normal elastin. Carbon 96-103 elastin Homo sapiens 82-89 7669085-6 1995 While alpha-carbons of human atherosclerotic elastin had shorter T1pC than normal elastin alpha carbons, carbons from hydrophobic amino acid side chains had longer T1pC for atherosclerotic then for normal elastin. Carbon 96-103 elastin Homo sapiens 82-89 7669085-6 1995 While alpha-carbons of human atherosclerotic elastin had shorter T1pC than normal elastin alpha carbons, carbons from hydrophobic amino acid side chains had longer T1pC for atherosclerotic then for normal elastin. Carbon 96-103 elastin Homo sapiens 82-89 7669085-6 1995 While alpha-carbons of human atherosclerotic elastin had shorter T1pC than normal elastin alpha carbons, carbons from hydrophobic amino acid side chains had longer T1pC for atherosclerotic then for normal elastin. Carbon 96-103 elastin Homo sapiens 82-89 7647779-3 1995 5, 10-Methylenetetrahydrofolate reductase (MTHFR) catalyzes the reduction of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, the predominant circulatory form of folate and carbon donor for the re-methylation of homocysteine to methionine. Carbon 185-191 methylenetetrahydrofolate reductase Homo sapiens 6-41 7647779-3 1995 5, 10-Methylenetetrahydrofolate reductase (MTHFR) catalyzes the reduction of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, the predominant circulatory form of folate and carbon donor for the re-methylation of homocysteine to methionine. Carbon 185-191 methylenetetrahydrofolate reductase Homo sapiens 43-48 7727418-2 1995 Yeast strains with null alleles of either of these two genes (delta rtg1, delta rtg2) cannot grow on acetate as the sole carbon source and are auxotrophic for glutamate and aspartate. Carbon 121-127 Rtg1p Saccharomyces cerevisiae S288C 68-72 7713942-2 1995 The effect is mimicked by phorbol esters, which directly activate protein kinase C. Using human embryonic kidney cells expressing individual muscarinic receptor subtypes, we found that stimulation of APPs release by the muscarinic agonist carbachol was only partially reduced by a specific inhibitor of protein kinase C (the bisindolylmaleimide GF 109203X), while the response to phorbol 12-myristate 13-acetate (PMA) was abolished. Carbon 81-82 cathepsin B Homo sapiens 200-204 9815997-5 1995 Conjugation of M3, most likely a glucuronide, was observed after incubation of C-labeled CAI and UDP-glucuronic acid with human liver 13,000 x g supernatant. Carbon 0-1 carbonic anhydrase 1 Homo sapiens 89-92 7867719-1 1995 Cell proliferation arrest at 37 degrees C (restrictive temperature) of the cell division cycle (cdc) mutants of Saccharomyces cerevisiae cdc28, cdc35, cdc19, cdc21, and cdc17 was correlated with carbon and energy uncoupling. Carbon 195-201 adenylate cyclase Saccharomyces cerevisiae S288C 144-149 7867719-1 1995 Cell proliferation arrest at 37 degrees C (restrictive temperature) of the cell division cycle (cdc) mutants of Saccharomyces cerevisiae cdc28, cdc35, cdc19, cdc21, and cdc17 was correlated with carbon and energy uncoupling. Carbon 195-201 thymidylate synthase Saccharomyces cerevisiae S288C 158-163 7703699-0 1995 Mapping of the spectral density function of a C alpha-H alpha bond vector from NMR relaxation rates of a 13C-labelled alpha-carbon in motilin. Carbon 124-130 motilin Homo sapiens 134-141 7703699-1 1995 The peptide hormone motilin was synthesised with a 13C-enriched alpha-carbon in the leucine at position 10. Carbon 70-76 motilin Homo sapiens 20-27 7723655-6 1995 MOD1 produced group results similar to the corresponding Simple model with an overall mean of 78.2% and a Complex/Simple (C/S) ratio of 0.99. Carbon 106-107 chromobox 1 Homo sapiens 0-4 7769966-2 1995 In the case of methyl 12-azido-9Z-octadecenoate (homoallylic), the carbon chemical shifts of the ethylenic C-9 and C-10 carbon nuclei are 133.092 and 124.596 ppm, respectively. Carbon 67-73 chromosome 12 open reading frame 57 Homo sapiens 115-119 7769966-2 1995 In the case of methyl 12-azido-9Z-octadecenoate (homoallylic), the carbon chemical shifts of the ethylenic C-9 and C-10 carbon nuclei are 133.092 and 124.596 ppm, respectively. Carbon 107-108 chromosome 12 open reading frame 57 Homo sapiens 115-119 7769966-2 1995 In the case of methyl 12-azido-9Z-octadecenoate (homoallylic), the carbon chemical shifts of the ethylenic C-9 and C-10 carbon nuclei are 133.092 and 124.596 ppm, respectively. Carbon 120-126 chromosome 12 open reading frame 57 Homo sapiens 115-119 7769966-3 1995 In methyl 9-azido-12Z-octadecenoate (bis homoallylic), the carbon chemical shift of the ethylenic C-12 and C-13 carbon nuclei are 128.118 and 131.243 ppm, respectively. Carbon 59-65 homeobox C13 Homo sapiens 107-111 7769966-3 1995 In methyl 9-azido-12Z-octadecenoate (bis homoallylic), the carbon chemical shift of the ethylenic C-12 and C-13 carbon nuclei are 128.118 and 131.243 ppm, respectively. Carbon 98-99 homeobox C13 Homo sapiens 107-111 7769966-3 1995 In methyl 9-azido-12Z-octadecenoate (bis homoallylic), the carbon chemical shift of the ethylenic C-12 and C-13 carbon nuclei are 128.118 and 131.243 ppm, respectively. Carbon 112-118 homeobox C13 Homo sapiens 107-111 8722121-0 1995 A carbon-skeleton walk: a novel double rearrangement of glutaryl-CoA catalyzed by the human methylmalonyl-CoA mutase. Carbon 2-8 methylmalonyl-CoA mutase Homo sapiens 92-116 7529505-0 1995 Deletion analysis of protein kinase C inactivation by calphostin C. Protein kinase C (PKC) undergoes specific inactivation by nanomolar concentrations of calphostin C. Carbon 36-37 protein kinase C alpha Bos taurus 86-89 8584670-2 1995 Structural requirements of a substrate for PAO are two positively charged amino groups, separated by a short carbon chain and an alkyl substituent on one or both nitrogen atoms. Carbon 109-115 polyamine oxidase Homo sapiens 43-46 7981185-6 1994 We analyzed at 9.4 T the resonances of unsaturated (UFA) and polyunsaturated (PUFA) carbons, the resonances of the carbons 19 and 21 (C19, C21) of cholesteryl esters (CE), the methine carbon peak of fatty acids (CH2)n, the choline peak from phospholipids (PL), and the glycerol peak from triglyceride (TG). Carbon 84-91 pumilio RNA binding family member 3 Homo sapiens 78-82 7981185-6 1994 We analyzed at 9.4 T the resonances of unsaturated (UFA) and polyunsaturated (PUFA) carbons, the resonances of the carbons 19 and 21 (C19, C21) of cholesteryl esters (CE), the methine carbon peak of fatty acids (CH2)n, the choline peak from phospholipids (PL), and the glycerol peak from triglyceride (TG). Carbon 84-90 pumilio RNA binding family member 3 Homo sapiens 78-82 11539187-0 1994 Infrared laser spectroscopy of the linear C13 carbon cluster. Carbon 46-52 homeobox C13 Homo sapiens 42-45 11539187-1 1994 The infrared absorption spectrum of a linear, 13-atom carbon cluster (C13) has been observed by using a supersonic cluster beam-diode laser spectrometer. Carbon 54-60 homeobox C13 Homo sapiens 70-73 8074202-4 1994 Analysis of dose-response curves showed that n-butyric acid (4 carbons in the molecule) was most effective for both insulin and glucagon secretion among the normal SCFAs tested. Carbon 63-70 LOC105613195 Ovis aries 116-123 7913929-2 1994 The results of competition experiments between the wild type and a GDH-deficient mutant during nutrient-limited growth and of direct enzyme measurements suggest that GDH is used in glutamate synthesis when the cell is limited for energy (and carbon) but ammonium and phosphate are present in excess, while the glutamine synthetase-glutamate synthase pathway is used when the cell is not under energy limitation. Carbon 242-248 glutamate dehydrogenase Escherichia coli 67-70 7986648-5 1994 Crystallographically averaged images of GroES single particle images indicate considerable variation in molecular shape, which is most likely due to varying molecular orientation on the carbon support film. Carbon 186-192 chaperonin GroES Escherichia coli 40-45 8113819-11 1994 Thus, the dopamine transporter requires an intact catechol with a primary ethylamine side chain for optimal activity relative to shorter side chain derivatives (side chains longer than two carbons were not tested), the 3-hydroxyl group of dopamine is the more critical hydroxyl group, and the beta rotamer of the extended conformation of dopamine is transported preferentially. Carbon 189-196 solute carrier family 6 member 3 Homo sapiens 10-30 8012523-3 1994 Compared to the spin trap 5,5-dimethyl-pyrroline-1-oxide, a higher lifetime of hydroxyl radical adducts and a higher selectivity related to the trapping of carbon-centered radicals was found. Carbon 156-162 spindlin 1 Homo sapiens 16-20 8119488-1 1994 The enzyme, glucose-6-phosphate dehydrogenase (G6PDH, EC1.1.1.49), has long been considered and studied as the archetypical X-linked "housekeeping" enzyme that is present in all cells, where it plays the key role in regulating carbon flow through the pentose phosphate pathway. Carbon 227-233 glucose-6-phosphate dehydrogenase Homo sapiens 12-45 8119488-1 1994 The enzyme, glucose-6-phosphate dehydrogenase (G6PDH, EC1.1.1.49), has long been considered and studied as the archetypical X-linked "housekeeping" enzyme that is present in all cells, where it plays the key role in regulating carbon flow through the pentose phosphate pathway. Carbon 227-233 glucose-6-phosphate dehydrogenase Homo sapiens 47-52 8280112-10 1994 The central role of pyruvate carboxylase in the conversion of glucose carbon into glutamine carbon was demonstrated by using a bicarbonate-free medium and measuring the fixation of 14CO2 from [14C]bicarbonate, which was recovered mostly at C-1 of glutamine plus glutamate. Carbon 70-76 pyruvate carboxylase, mitochondrial Cavia porcellus 20-40 8280112-10 1994 The central role of pyruvate carboxylase in the conversion of glucose carbon into glutamine carbon was demonstrated by using a bicarbonate-free medium and measuring the fixation of 14CO2 from [14C]bicarbonate, which was recovered mostly at C-1 of glutamine plus glutamate. Carbon 183-184 pyruvate carboxylase, mitochondrial Cavia porcellus 20-40 8166960-1 1994 Highly sensitive biosensors for phenolic compounds, based on the incorporation of the enzyme tyrosinase within metal-dispersed carbon paste matrices are described. Carbon 127-133 tyrosinase Homo sapiens 93-103 7505388-2 1993 Mutations in the GEF1 gene cause cells to grow slowly on rich media containing carbon sources utilized by respiration. Carbon 79-85 Gef1p Saccharomyces cerevisiae S288C 17-21 7505388-4 1993 Gef1- mutants also fail to grow on a fermentable carbon source, glucose, when iron is reduced to low concentrations in the medium, suggesting that the GEF1 gene is required for efficient metabolism of iron during growth on fermentable as well as respired carbon sources. Carbon 49-55 Gef1p Saccharomyces cerevisiae S288C 0-4 7505388-4 1993 Gef1- mutants also fail to grow on a fermentable carbon source, glucose, when iron is reduced to low concentrations in the medium, suggesting that the GEF1 gene is required for efficient metabolism of iron during growth on fermentable as well as respired carbon sources. Carbon 255-261 Gef1p Saccharomyces cerevisiae S288C 0-4 7505388-4 1993 Gef1- mutants also fail to grow on a fermentable carbon source, glucose, when iron is reduced to low concentrations in the medium, suggesting that the GEF1 gene is required for efficient metabolism of iron during growth on fermentable as well as respired carbon sources. Carbon 255-261 Gef1p Saccharomyces cerevisiae S288C 151-155 7901008-1 1993 Phosphoglucose isomerase pgi1-deletion mutants of Saccharomyces cerevisiae cannot grow on glucose as the sole carbon source and are even inhibited by glucose. Carbon 110-116 glucose-6-phosphate isomerase Saccharomyces cerevisiae S288C 25-29 8344434-1 1993 Mouse IgG1, IgG2a, and IgG2b proteins have been selectively labeled with 13C at the carbonyl carbon of His, Met, Trp or Tyr residue and used to prepare the corresponding Fc fragments by limited proteolysis. Carbon 84-90 immunoglobulin heavy constant gamma 2B Mus musculus 23-28 8349103-1 1993 Recessive mutations of GAL11 in Saccharomyces cerevisiae cause pleiotropic defects that include weak fermentation of galactose, alpha-specific sterility and slow growth on nonfermentable carbon sources. Carbon 187-193 Gal11p Saccharomyces cerevisiae S288C 23-28 8508783-1 1993 Wild-type Saccharomyces cerevisiae and a strain carrying a deletion in the glucose-6-phosphate-isomerase gene (pgi1) were grown in carbon-limited continuous cultures on a mixture of fructose and galactose. Carbon 131-137 glucose-6-phosphate isomerase Saccharomyces cerevisiae S288C 75-104 8508783-1 1993 Wild-type Saccharomyces cerevisiae and a strain carrying a deletion in the glucose-6-phosphate-isomerase gene (pgi1) were grown in carbon-limited continuous cultures on a mixture of fructose and galactose. Carbon 131-137 glucose-6-phosphate isomerase Saccharomyces cerevisiae S288C 111-115 7683726-2 1993 As described in the preceding paper, yeast require a functional AAC2 (or AAC1) to grow on a non-fermentable carbon source. Carbon 108-114 ADP/ATP carrier protein AAC1 Saccharomyces cerevisiae S288C 73-77 8099891-3 1993 Our results point to an involvement in the life cycle of the PHO2 activator and the PHO85-negative factor and to a reduced ability of the negative pho regulatory mutants, pho80 and pho85, to grow on non-fermentable carbon sources. Carbon 215-221 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 84-89 8099891-3 1993 Our results point to an involvement in the life cycle of the PHO2 activator and the PHO85-negative factor and to a reduced ability of the negative pho regulatory mutants, pho80 and pho85, to grow on non-fermentable carbon sources. Carbon 215-221 cyclin-dependent serine/threonine-protein kinase PHO85 Saccharomyces cerevisiae S288C 181-186 12231708-10 1993 Therefore, SPS activity is a major determinant of the partitioning of photosynthetically fixed carbon in the leaf and in the whole plant. Carbon 95-101 sucrose-phosphate synthase Solanum lycopersicum 11-14 12231708-14 1993 We conclude that the level of SPS in the leaves plays a pivotal role in carbon partitioning. Carbon 72-78 sucrose-phosphate synthase Solanum lycopersicum 30-33 8207906-2 1993 Resulting from the use of Normaze preparation in combination with Bifidumbacterin adsorbed on SKN carbon sorbent, the composition of intestinal microflora has restored, bile structure improved. Carbon 98-104 hedgehog acyltransferase Homo sapiens 94-97 1478780-3 1992 This strategy permitted the carbon atom spacing between the P1 and the P3 inhibitor side chains to be systematically varied so as to produce inhibitors with 15-, 16-, and 17-membered ring systems. Carbon 28-34 crystallin gamma F, pseudogene Homo sapiens 60-73 24234502-3 1992 GC/MS studies also identified several n-alkanes with carbon numbers from C19 to C33 in the sample. Carbon 53-59 CD82 molecule Homo sapiens 80-83 1597433-1 1992 Saccharomyces cerevisiae byp1-3 mutants displayed a long lag phase when shifted from a nonfermentable carbon source to a medium containing glucose. Carbon 102-108 alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1 Saccharomyces cerevisiae S288C 25-31 1597433-3 1992 As opposed to wild-type cells, the addition of glucose to cells of the byp1-3 mutant grown on nonfermentable carbon sources did not induce a cyclic AMP signal. Carbon 109-115 alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1 Saccharomyces cerevisiae S288C 71-77 1543727-10 1992 The platelet PLA2 is most effectively inhibited by negatively charged inhibitors having a relatively short (four or more carbon atoms) alkylchain on position one and a acylamino chain of 14 carbon atoms on position two. Carbon 121-127 phospholipase A2 group IIA Homo sapiens 13-17 1543727-10 1992 The platelet PLA2 is most effectively inhibited by negatively charged inhibitors having a relatively short (four or more carbon atoms) alkylchain on position one and a acylamino chain of 14 carbon atoms on position two. Carbon 190-196 phospholipase A2 group IIA Homo sapiens 13-17 1543727-13 1992 The largest discrimination in inhibition between the human platelet and the human pancreatic PLA2 is obtained with inhibitors with a negatively charged phosphoglycol headgroup, an alkyl chain of four carbon atoms on position one and a long acylamino chain of 14-16 carbon atoms on position two. Carbon 200-206 phospholipase A2 group IIA Homo sapiens 93-97 1543727-13 1992 The largest discrimination in inhibition between the human platelet and the human pancreatic PLA2 is obtained with inhibitors with a negatively charged phosphoglycol headgroup, an alkyl chain of four carbon atoms on position one and a long acylamino chain of 14-16 carbon atoms on position two. Carbon 265-271 phospholipase A2 group IIA Homo sapiens 93-97 1586588-5 1992 The differentiation of the enantiotopic ring carbon atoms (product enantioselectivity) in the smallest aliphatic meso-oxirane, cis-2,3-dimethyloxirane, leads to (2R;3R)-butane-2,3-diol with ee = 86%. Carbon 45-51 suppressor of cytokine signaling 2 Homo sapiens 127-132 1807160-4 1991 Individual C-10 through C-14 alkyl sulfates, C-11 through C-14 alkyl sulfonates, sodium N-lauroyl-N-methyl-taurine, N-lauroylsarcosine, sodium laurate, or benzyldimethyl-n-hexadecylammonium chloride were substituted for SDS in equilibration buffer, gel buffer, and upper running buffer. Carbon 24-25 chromosome 12 open reading frame 57 Homo sapiens 11-15 1923818-9 1991 In addition, Kl-GAL11 complements a gal11-defect in S. cerevisiae by partially restoring induction of GAL1 expression, growth on nonfermentable carbon sources, and phosphorylation of GAL4. Carbon 144-150 Gal11p Saccharomyces cerevisiae S288C 16-21 1796394-1 1991 The incubation of purified human factor XII (Hageman factor [HF]) in the presence of long-chain saturated fatty acids (FA) like stearate (C-18) or behenate (C-22) resulted in a time-dependent increase of amidolytic activity. Carbon 138-139 coagulation factor XII Homo sapiens 45-59 1796394-1 1991 The incubation of purified human factor XII (Hageman factor [HF]) in the presence of long-chain saturated fatty acids (FA) like stearate (C-18) or behenate (C-22) resulted in a time-dependent increase of amidolytic activity. Carbon 138-139 coagulation factor XII Homo sapiens 61-63 1796394-1 1991 The incubation of purified human factor XII (Hageman factor [HF]) in the presence of long-chain saturated fatty acids (FA) like stearate (C-18) or behenate (C-22) resulted in a time-dependent increase of amidolytic activity. Carbon 157-158 coagulation factor XII Homo sapiens 45-59 1652057-5 1991 Carbon regulation of GDH2 was found to be normal in hxk2, hap3, and hap4 strains and to be only slightly altered in a ssn6 strain; thus, in comparison with the regulation of previously identified glucose-repressed genes, a new pathway appears to be involved in the regulation of GDH2. Carbon 0-6 transcription factor HAP4 Saccharomyces cerevisiae S288C 68-72 1928735-2 1991 By using this phenomenon to preconcentrate the drug at a glassy carbon electrode prior to differential-pulse voltammetric measurements, sensitivity at the ppb level is readily achieved. Carbon 64-70 histatin 1 Homo sapiens 155-158 2043623-5 1991 The conformation of the bound substrate stereoelectronically favors proton transfer from substrate carbon to the syn orbital of Glu-165. Carbon 99-105 synemin Homo sapiens 113-116 2175624-1 1990 The present study examined the hemodynamic actions of a non-guanylate cyclase linked or "clearance" atrial natriuretic factor (ANF) receptor ligand--des[Gln116Ser117Gly118Leu119Gly120] ANF 102-121 (C-ANF 4-23)--in conscious sheep. Carbon 198-199 natriuretic peptides A Ovis aries 100-125 1979298-10 1990 S. cerevisiae cells transformed with centromere plasmids carrying the GAM1 gene fused to promoters of different S. cerevisiae genes, namely GAL1, PDC1 and ADH1, efficiently secrete GAM and are able to grow with soluble starch as a sole carbon source. Carbon 236-242 SWI/SNF catalytic subunit SNF2 Saccharomyces cerevisiae S288C 70-74 1976062-10 1990 Increasing the ratio of NADH to NADPH in incubations containing lung microsomes and (S)-nicotine decreased the yield of the iminium ion, confirming the inhibitory effect of cytochrome b5 on the P-450 2-catalyzed alpha-carbon oxidation reaction. Carbon 218-224 cytochrome b5 Oryctolagus cuniculus 173-186 2345154-7 1990 These results also reinforce the conclusion that biosynthetic AHAS isozymes of low R (1 to 2) are a special adaptation for heterotrophic growth on certain poor carbon sources. Carbon 160-166 ilvB acetolactate synthase like Homo sapiens 62-66 2111350-4 1990 In addition, class I IFN is involved because IFN-alpha and IFN-beta act synergistically on TNF-alpha mediated lysis of 3LL-R cells within 18 h. Moreover, anticlass I IFN antibodies abolish the cytolytic capacity of Poly I:C-activated macrophages. Carbon 222-223 interferon alpha Mus musculus 45-54 2111350-4 1990 In addition, class I IFN is involved because IFN-alpha and IFN-beta act synergistically on TNF-alpha mediated lysis of 3LL-R cells within 18 h. Moreover, anticlass I IFN antibodies abolish the cytolytic capacity of Poly I:C-activated macrophages. Carbon 222-223 interferon beta 1, fibroblast Mus musculus 59-67 2193978-1 1990 The Isoparaffins covered in this manuscript are branched aliphatic hydrocarbons with a carbon skeleton length ranging from approximately C10 to C15. Carbon 72-78 placenta associated 8 Homo sapiens 144-147 2204679-4 1990 These results make it unlikely that the WHI2 product acts as an inhibitor of cell proliferation which is activated upon carbon starvation. Carbon 120-126 Whi2p Saccharomyces cerevisiae S288C 40-44 1970528-6 1990 Both butyrate and valerate isomers with branched carbon chains had larger insulin releasing activity than isomers with straight carbon chains. Carbon 49-55 LOC105613195 Ovis aries 74-81 2149071-2 1990 Fluorocarbon-coated surfaces varying in the relative proportions of CF, CF2, and CF3 groups and in the ratio of fluorine to carbon were prepared by RFGD treatment of poly(ethylene terephthalate) (PET) films with tetrafluoroethylene or perfluoropropane. Carbon 6-12 ATPase H+ transporting accessory protein 1 Homo sapiens 72-75 33806007-4 2021 We characterized the activation of mouse TRPA1 by non-electrophilic alkylphenols (APs) of different carbon chain lengths in the para position of the aromatic ring. Carbon 100-106 transient receptor potential cation channel, subfamily A, member 1 Mus musculus 41-46 33803036-1 2021 This paper fabricates a carbon nanotube (CNT ) film-reinforced mesophase pitch-based carbon (CNTF/MPC) nanocomposite by using a hot-pressing carbonization method. Carbon 24-30 ciliary neurotrophic factor Homo sapiens 93-97 33803036-1 2021 This paper fabricates a carbon nanotube (CNT ) film-reinforced mesophase pitch-based carbon (CNTF/MPC) nanocomposite by using a hot-pressing carbonization method. Carbon 85-91 ciliary neurotrophic factor Homo sapiens 93-97 33802362-2 2021 The association between maternal genetic polymorphism MTHFR(677)C>T and anthropometry at birth has been widely studied because of its key role in the one-carbon cycle. Carbon 154-160 methylenetetrahydrofolate reductase Homo sapiens 54-59 32796638-1 2020 Herein, a novel electrochemical glucose biosensor based on glucose oxidase (GOx) immobilized on a surface containing platinum nanoparticles (PtNPs) electrodeposited on poly(Azure A) (PAA) previously electropolymerized on activated screen-printed carbon electrodes (GOx-PtNPs-PAA-aSPCEs) is reported. Carbon 246-252 hydroxyacid oxidase 1 Homo sapiens 59-74 32796638-1 2020 Herein, a novel electrochemical glucose biosensor based on glucose oxidase (GOx) immobilized on a surface containing platinum nanoparticles (PtNPs) electrodeposited on poly(Azure A) (PAA) previously electropolymerized on activated screen-printed carbon electrodes (GOx-PtNPs-PAA-aSPCEs) is reported. Carbon 246-252 hydroxyacid oxidase 1 Homo sapiens 76-79 32047704-7 2020 Additionally, we demonstrate that impaired osteoclast differentiation in IgSF11-deficient cells is rescued by full-length IgSF11 and that the IgSF11-PSD-95 interaction requires the 75 C-terminal amino acids of IgSF11. Carbon 184-185 discs large MAGUK scaffold protein 4 Mus musculus 149-155 25764502-0 2015 The influence of carbon sources on the expression of the recA gene and genotoxicity detection by an Acinetobacter bioreporter. Carbon 17-23 RAD51 recombinase Homo sapiens 57-61 25764502-2 2015 This paper evaluated the influence of carbon sources on the recA gene (ACIAD1385) in a DNA damage-inducible recA::luxCDABE Acinetobacter bioreporter and optimized the induction conditions for its practical application in environmental monitoring. Carbon 38-44 RAD51 recombinase Homo sapiens 60-64 25764502-2 2015 This paper evaluated the influence of carbon sources on the recA gene (ACIAD1385) in a DNA damage-inducible recA::luxCDABE Acinetobacter bioreporter and optimized the induction conditions for its practical application in environmental monitoring. Carbon 38-44 RAD51 recombinase Homo sapiens 108-112 25764502-4 2015 A reverse transcription quantitative PCR (RT-qPCR) showed the different expression levels of the DNA damage-inducible gene recA (p < 0.05), suggesting that carbon sources influenced the DNA damage response in the Acinetobacter bioreporter at the transcriptional level. Carbon 159-165 RAD51 recombinase Homo sapiens 123-127 9714758-6 1998 Using beta-lactamase as a reporter, we show that the FLD1 promoter (PFLD1) is strongly and independently induced by either methanol as sole carbon source (with ammonium sulfate as nitrogen source) or methylamine as sole nitrogen source (with glucose as carbon source). Carbon 140-146 seipin Saccharomyces cerevisiae S288C 53-57 9714758-6 1998 Using beta-lactamase as a reporter, we show that the FLD1 promoter (PFLD1) is strongly and independently induced by either methanol as sole carbon source (with ammonium sulfate as nitrogen source) or methylamine as sole nitrogen source (with glucose as carbon source). Carbon 253-259 seipin Saccharomyces cerevisiae S288C 53-57 34710461-2 2022 Under different carbon to nitrogen (C/N) ratios, the nitrogen removal efficiency (NRE) and carbon source efficiency (CSE) of denitrification coupled with SDHC (DN-SDHC) were distinctly higher than that of denitrification alone (DN). Carbon 16-22 succinate dehydrogenase complex subunit C Homo sapiens 154-158 34710461-2 2022 Under different carbon to nitrogen (C/N) ratios, the nitrogen removal efficiency (NRE) and carbon source efficiency (CSE) of denitrification coupled with SDHC (DN-SDHC) were distinctly higher than that of denitrification alone (DN). Carbon 16-22 succinate dehydrogenase complex subunit C Homo sapiens 160-167 34710461-2 2022 Under different carbon to nitrogen (C/N) ratios, the nitrogen removal efficiency (NRE) and carbon source efficiency (CSE) of denitrification coupled with SDHC (DN-SDHC) were distinctly higher than that of denitrification alone (DN). Carbon 91-97 succinate dehydrogenase complex subunit C Homo sapiens 154-158 34710461-2 2022 Under different carbon to nitrogen (C/N) ratios, the nitrogen removal efficiency (NRE) and carbon source efficiency (CSE) of denitrification coupled with SDHC (DN-SDHC) were distinctly higher than that of denitrification alone (DN). Carbon 91-97 succinate dehydrogenase complex subunit C Homo sapiens 160-167 34710461-5 2022 Although SDHC has no redox capacity to donate electron for denitrification, its higher conductivity enabled the acceleration of extracellular electron transfer from carbon source to denitrifiers. Carbon 165-171 succinate dehydrogenase complex subunit C Homo sapiens 9-13 34384964-2 2022 Here, we report a facile self-catalyzed growth strategy for in situ encapsulation of Co nanoparticles with N-doped carbon nanotubes (NCNTs) on Ni foam (NF) (Co/NCNTs-NF-T; T represents the pyrolysis temperature). Carbon 115-121 neurofascin Homo sapiens 143-155 34904840-2 2022 Double Rubottom oxidation of the bis(silyl enol ether) derived from a tricarbocyclic diketone effectively installed a bridgehead olefin and C-5/C-13 hydroxy groups in a one-step operation. Carbon 140-141 homeobox C13 Homo sapiens 144-148 34737163-4 2022 Microbial analysis showed that the succession of bacterial and fungal community was significantly influenced by total carbon (TN), pH and MC (P < 0.05). Carbon 118-124 C-type lectin domain family 3 member B Bos taurus 126-128 34764205-0 2022 The protein kinase activity of NME7 activates Wnt/beta-Catenin signaling to promote one-carbon metabolism in hepatocellular carcinoma. Carbon 88-94 NME/NM23 family member 7 Homo sapiens 31-35 34764205-8 2022 Furthermore, MTHFD2, the key enzyme in one-carbon metabolism, was a target gene of beta-catenin and mediated the effects of NME7. Carbon 43-49 catenin (cadherin associated protein), beta 1 Mus musculus 83-95 34764205-11 2022 Collectively, this study emphasizes the crucial roles of NME7 protein kinase activity in promoting Wnt/beta-catenin signaling and one-carbon metabolism, suggesting NME7 and MTHFD2 as potential therapeutic targets for HCC. Carbon 134-140 NME/NM23 family member 7 Homo sapiens 57-61 34764205-11 2022 Collectively, this study emphasizes the crucial roles of NME7 protein kinase activity in promoting Wnt/beta-catenin signaling and one-carbon metabolism, suggesting NME7 and MTHFD2 as potential therapeutic targets for HCC. Carbon 134-140 NME/NM23 family member 7 Homo sapiens 164-168 34764205-11 2022 Collectively, this study emphasizes the crucial roles of NME7 protein kinase activity in promoting Wnt/beta-catenin signaling and one-carbon metabolism, suggesting NME7 and MTHFD2 as potential therapeutic targets for HCC. Carbon 134-140 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase Homo sapiens 173-179 34970801-8 2022 Distance of Tm3+ to terminal methyl carbons is a key determinant for sustaining BIRDS-temperature sensitivity without compromising CEST-pH contrast, however water solubility was influenced by introduction of hydrophobic methyl groups and hydrophilic carboxylate. Carbon 36-43 tropomyosin 3 Homo sapiens 12-15 34870421-0 2021 Molecular Functionalization and Emergence of Long-Range Spin-Dependent Phenomena in Two-Dimensional Carbon Nanotube Networks. Carbon 100-106 spindlin 1 Homo sapiens 56-60 34784166-2 2021 Herein, we develop a lithiophilic Nb2O5-embedded three-dimensional (3D) carbon nanofiber network (Nb2O5-CNF) as a scaffold to preload molten Li for the fabrication of dendrite-free composite anode. Carbon 72-78 NPHS1 adhesion molecule, nephrin Homo sapiens 104-107 34787998-0 2021 Carbon Nanotube-Based Field-Effect Transistor-Type Sensor with a Sensing Gate for Ppb-Level Formaldehyde Detection. Carbon 0-6 histatin 1 Homo sapiens 82-85 34560601-1 2021 Crevice corrosion of X80 carbon steel in simulated seawater with the presence of SRB was studied by surface analysis and electrochemical measurements. Carbon 25-31 chaperonin containing TCP1 subunit 4 Homo sapiens 81-84 34215932-4 2021 SHMT2 is a PLP-dependent tetrameric enzyme that catalyzes the reversible transition from serine to glycine, thus promoting the production of one-carbon units that are indispensable for cell growth and regulation of the redox and epigenetic states of cells. Carbon 145-151 serine hydroxymethyltransferase 2 Homo sapiens 0-5 34937899-1 2021 Spin-ordered electronic states in hydrogen-terminated zigzag nanographene give rise to magnetic quantum phenomena1,2 that have sparked renewed interest in carbon-based spintronics3,4. Carbon 155-161 spindlin 1 Homo sapiens 0-4 34378544-4 2021 To fill this knowledge gap, we first used a Random Forest algorithm to predict the spatio-temporal patterns of RAsoil from 1981 to 2017 based on the most updated Global Soil Respiration Database (v5) with global environmental variables; calculated carbon allocation from photosynthesis to RAsoil (CAB) as a fraction of gross primary production; and assessed its temporal and spatial patterns in global forest ecosystems. Carbon 248-254 neural proliferation, differentiation and control 1 Homo sapiens 297-300 34378544-8 2021 Combined with carbon use efficiency, our CAB results offer a completely independent approach to quantify global aboveground autotropic respiration spatially and temporally, and could provide crucial insights into carbon flux partitioning and global carbon cycling under climate change. Carbon 213-219 neural proliferation, differentiation and control 1 Homo sapiens 41-44 34378544-8 2021 Combined with carbon use efficiency, our CAB results offer a completely independent approach to quantify global aboveground autotropic respiration spatially and temporally, and could provide crucial insights into carbon flux partitioning and global carbon cycling under climate change. Carbon 249-255 neural proliferation, differentiation and control 1 Homo sapiens 41-44 34951281-5 2021 Compared with CK, ST3 and ST4 treatments significantly increased the content of mineral-bound organic carbon (MOC) in 250-2000 mum aggregates and the content of fine particulate organic carbon (fPOC) in 53-250 mum aggregates. Carbon 102-108 cytidine/uridine monophosphate kinase 1 Homo sapiens 14-16 34601206-2 2021 Then, a highly sensitive non-enzymatic salvianic acid A (SAA) electrochemical sensor was fabricated by modifying HKUST-1 @ (RGO-MWCNT) on a glassy carbon electrode, taking full advantage of the synergistic effect between the redox catalytic capacity of Cu2+ and the electrical conductivity of carbon materials. Carbon 147-153 serum amyloid A1 cluster Homo sapiens 57-60 34601206-2 2021 Then, a highly sensitive non-enzymatic salvianic acid A (SAA) electrochemical sensor was fabricated by modifying HKUST-1 @ (RGO-MWCNT) on a glassy carbon electrode, taking full advantage of the synergistic effect between the redox catalytic capacity of Cu2+ and the electrical conductivity of carbon materials. Carbon 293-299 serum amyloid A1 cluster Homo sapiens 57-60 34585791-2 2021 This research reports for the first time the microwave-assisted synthesis of CdS/carbon/MoS x hybrids and the subsequent utilization of such systems as photocatalysts for 4-nitrophenol degradation. Carbon 81-87 MOS proto-oncogene, serine/threonine kinase Homo sapiens 88-91 34708988-5 2021 (2)The sequence of distribution of soil organic carbon content with CK, T1, and T2 treatments in different slope positions was downslope position>middle slope position>upslope position, while the soil organic carbon content of T3 and T4 treatments was the highest at the middle slope position. Carbon 48-54 cytidine/uridine monophosphate kinase 1 Homo sapiens 68-70 34708988-5 2021 (2)The sequence of distribution of soil organic carbon content with CK, T1, and T2 treatments in different slope positions was downslope position>middle slope position>upslope position, while the soil organic carbon content of T3 and T4 treatments was the highest at the middle slope position. Carbon 209-215 cytidine/uridine monophosphate kinase 1 Homo sapiens 68-70 34708988-6 2021 (3)With the decrease of slope, the soluble organic carbon content of CK, T1, T2, and T3 treated soil showed an increasing trend; the carbon content of CK, T1, T2, and T4 treated soil microorganisms increased; while the distribution of T3 treated soil microbial carbon on the slope was highest at the middle slope followed by the lower slope. Carbon 51-57 cytidine/uridine monophosphate kinase 1 Homo sapiens 69-71 34708988-6 2021 (3)With the decrease of slope, the soluble organic carbon content of CK, T1, T2, and T3 treated soil showed an increasing trend; the carbon content of CK, T1, T2, and T4 treated soil microorganisms increased; while the distribution of T3 treated soil microbial carbon on the slope was highest at the middle slope followed by the lower slope. Carbon 133-139 cytidine/uridine monophosphate kinase 1 Homo sapiens 151-153 34708988-6 2021 (3)With the decrease of slope, the soluble organic carbon content of CK, T1, T2, and T3 treated soil showed an increasing trend; the carbon content of CK, T1, T2, and T4 treated soil microorganisms increased; while the distribution of T3 treated soil microbial carbon on the slope was highest at the middle slope followed by the lower slope. Carbon 261-267 cytidine/uridine monophosphate kinase 1 Homo sapiens 69-71 34668896-3 2021 Herein, 3D interconnected hierarchical porous carbon aerogels (CNFAs) through engineering the pyrolysis chemistry of CNF are developed. Carbon 46-52 NPHS1 adhesion molecule, nephrin Homo sapiens 117-120 34650043-2 2021 Here, the effect of co-segregation of carbon and boron on the depletion of aluminum at a Sigma5 (3 1 0 )(0 0 1) tilt grain boundary in a alpha - Fe-4 at%Al bicrystal is studied by combining atomic resolution scanning transmission electron microscopy, atom probe tomography and density functional theory calculations. Carbon 38-44 adaptor related protein complex 5 subunit sigma 1 Homo sapiens 89-95 34650056-5 2021 In contrast to carbon nanotubes, where nanotube chirality determines spin-orbit coupling breaking the SU(4) symmetry of the electronic states relevant for the Kondo effect, we study a planar carbon material where a small spin-orbit coupling of nominally flat graphene is enhanced by zero-point out-of-plane phonons. Carbon 191-197 spindlin 1 Homo sapiens 221-225 34640282-5 2021 EH36 and FH36 ship plate steel had higher impact toughness due to lower carbon (C) and silicon (Si) content and higher manganese (Mn) content than E36 ship plate steel. Carbon 72-78 inositol polyphosphate-5-phosphatase D Homo sapiens 14-18 34640282-5 2021 EH36 and FH36 ship plate steel had higher impact toughness due to lower carbon (C) and silicon (Si) content and higher manganese (Mn) content than E36 ship plate steel. Carbon 80-81 inositol polyphosphate-5-phosphatase D Homo sapiens 14-18 34640282-9 2021 The fatigue crack growth rate of E36 ship plate steel was higher than that of EH36 and FH36 ship plate steel due to its higher carbon content and obviously smaller grain size. Carbon 127-133 inositol polyphosphate-5-phosphatase D Homo sapiens 92-96 34620864-6 2021 Therefore, transcription factor Crp appears to work in concert with CytR and RpoH, serving a dual role in sensing both carbon availability and metabolic flux towards DNA and RNA. Carbon 119-125 catabolite gene activator protein Escherichia coli 32-35 34691085-13 2021 Neutralization of either IL-10 or monocytes can augment Poly I:C-based treatments and enhance T cell cytotoxicity. Carbon 63-64 interleukin 10 Homo sapiens 25-30 34101628-12 2021 IL-17A significantly decreased both IL-32 beta/gamma/epsilon mRNA and cell-associated IL-32 protein levels induced upon TNF-alpha and Poly I:C triggering. Carbon 141-142 interleukin 17A Homo sapiens 0-6 34528656-1 2021 In order to increase the capacity and improve the sluggish Na+-reaction kinetics of anodes as sodium ion capacitors (SICs), a Ti2Nb2O9/CNF self-standing film electrode comprised of Ti2Nb2O9 nanosheets and carbon nanofibers has been fabricated via electrospinning HTiNbO5 nanosheets with PAN and subsequent carbonization treatment. Carbon 205-211 NPHS1 adhesion molecule, nephrin Homo sapiens 135-138 34494368-2 2021 Herein, a facile yet robust strategy is reported to rationally design single iron active centers synergized with local S atoms in metal-organic frameworks derived from hierarchically porous carbon nanorods (Fe/N,S-HC). Carbon 190-196 general transcription factor IIE subunit 1 Homo sapiens 207-209 34640033-6 2021 Furthermore, the authors present developments and applications of ANNs for prediction of compressive strength and flexural strength of carbon nanotubes/carbon nanofibers (CNT/CNF) reinforced concrete using experimental results for the learning process. Carbon 135-141 NPHS1 adhesion molecule, nephrin Homo sapiens 175-178 34640033-6 2021 Furthermore, the authors present developments and applications of ANNs for prediction of compressive strength and flexural strength of carbon nanotubes/carbon nanofibers (CNT/CNF) reinforced concrete using experimental results for the learning process. Carbon 152-158 NPHS1 adhesion molecule, nephrin Homo sapiens 175-178 34516595-7 2021 The electrical control on spin polarization is realized in pure-carbon systems, showing great application potential. Carbon 64-70 spindlin 1 Homo sapiens 26-30 34263532-1 2021 A new practical method for construction of 3D porous carbon was developed through molecular design via one step synthesis from commercially available carbon tetrabromide and bis(trimethylsilyl)acetylene on a gram-scale, and the obtained porous carbon has well-defined sp 1 -sp 3 all-carbon structure (C 13 ), high stability and also high surface area. Carbon 53-59 homeobox C13 Homo sapiens 301-305 34263532-1 2021 A new practical method for construction of 3D porous carbon was developed through molecular design via one step synthesis from commercially available carbon tetrabromide and bis(trimethylsilyl)acetylene on a gram-scale, and the obtained porous carbon has well-defined sp 1 -sp 3 all-carbon structure (C 13 ), high stability and also high surface area. Carbon 244-250 homeobox C13 Homo sapiens 301-305 34263532-1 2021 A new practical method for construction of 3D porous carbon was developed through molecular design via one step synthesis from commercially available carbon tetrabromide and bis(trimethylsilyl)acetylene on a gram-scale, and the obtained porous carbon has well-defined sp 1 -sp 3 all-carbon structure (C 13 ), high stability and also high surface area. Carbon 283-289 homeobox C13 Homo sapiens 301-305 34556996-6 2021 Moreover, the combination of carbon ion beam irradiation and miRNA-200c mimic increased the expression of apoptosis-related gene BAX, autophagy-related genes Beclin-1 and p62, addition of gemcitabine (GEM) further enhanced the expression of these genes. Carbon 29-35 beclin 1 Homo sapiens 158-166 34556996-6 2021 Moreover, the combination of carbon ion beam irradiation and miRNA-200c mimic increased the expression of apoptosis-related gene BAX, autophagy-related genes Beclin-1 and p62, addition of gemcitabine (GEM) further enhanced the expression of these genes. Carbon 29-35 nucleoporin 62 Homo sapiens 171-174 34496877-3 2021 In this work, a dual-quenched electrochemiluminescence (ECL) immunosensor has been fabricated for ultrasensitive detection of RBP4 by combining zeolitic imidazolate framework-67/AuPt-supported luminol (luminol@AuPt/ZIF-67) with MnO2 nanosheets-grown on carbon nanotubes (MnO2@CNTs). Carbon 253-259 retinol binding protein 4 Homo sapiens 126-130 34490841-3 2021 The carbon molecules evaporate at very low fields of 5.9 V/nm, while S requires a considerably higher evaporation field of 23.4 V/nm. Carbon 4-10 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Homo sapiens 59-61 34081950-7 2021 Sequencing of the Hmgcr promoter in SHR and WKY strains reveals three variations: A-405G, C-62 T and a 11 bp insertion (-398_-388insTGCGGTCCTCC) in SHR. Carbon 90-91 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus 18-23 34502300-3 2021 Methylenetetrahydrofolate reductase (MTHFR) is the enzyme catalyzing the irreversible conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate that can control folate cofactor distributions and modulate the partitioning of intracellular one-carbon moieties. Carbon 257-263 methylenetetrahydrofolate reductase Homo sapiens 0-35 34502300-3 2021 Methylenetetrahydrofolate reductase (MTHFR) is the enzyme catalyzing the irreversible conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate that can control folate cofactor distributions and modulate the partitioning of intracellular one-carbon moieties. Carbon 257-263 methylenetetrahydrofolate reductase Homo sapiens 37-42 34578533-3 2021 Several instrumental techniques have been employed to characterize the as-prepared AC (Db-s). Carbon 83-85 proline rich protein HaeIII subfamily 1 Homo sapiens 87-91 34578533-9 2021 The maximum percent of RhB dye removal by AC (Db-s) was 98.4% at an aqueous solution of 20 ppm, pH 8.5, an adsorbent dose of 0.03 g, and a time of 5 min. Carbon 42-44 proline rich protein HaeIII subfamily 1 Homo sapiens 46-50 34443450-6 2021 KL had high carbon content but low oxygen and methoxyl contents compared to MWLs. Carbon 12-18 klotho Homo sapiens 0-2 34343498-6 2021 SELW promoted purine salvage pathways and inhibited one-carbon metabolism by recruiting an E3 ubiquitin ligase, tripartite motif-containing protein 21, which controlled the stability of serine hydroxymethyltransferase 2. Carbon 56-62 serine hydroxymethyltransferase 2 Homo sapiens 186-219 34445260-5 2021 Additionally, sucrose, commonly added to the regeneration media as a carbon source, plays a signaling role and has been recently shown to interact with CK and auxin and to affect the efficiency of shoot regeneration. Carbon 69-75 cytidine/uridine monophosphate kinase 1 Homo sapiens 152-154 34476002-2 2021 In a variety of human tumours, including hepatocellular carcinoma (HCC), breast cancer and non-small-cell lung cancer (NSCLC), a large amount of carbon is reused in serine/glycine biosynthesis, accompanied by higher expression of the key glycine synthetic enzyme mitochondrial serine hydroxymethyltransferase 2 (SHMT2). Carbon 145-151 serine hydroxymethyltransferase 2 Homo sapiens 312-317 34436069-2 2021 We investigated the immobilization of glucose oxidase (GOx) on a new composite nanomaterial poly(3,4-ethylenedioxythiophene): polystyrene sulfonate (PEDOT:PSS)/titanium carbide,(Ti3C2)/graphene quantum dots(GQD) modified screen-printed carbon electrode (SPCE) for glucose sensing. Carbon 236-242 hydroxyacid oxidase 1 Homo sapiens 38-53 34436069-2 2021 We investigated the immobilization of glucose oxidase (GOx) on a new composite nanomaterial poly(3,4-ethylenedioxythiophene): polystyrene sulfonate (PEDOT:PSS)/titanium carbide,(Ti3C2)/graphene quantum dots(GQD) modified screen-printed carbon electrode (SPCE) for glucose sensing. Carbon 236-242 hydroxyacid oxidase 1 Homo sapiens 55-58 34445210-14 2021 The present study illustrates that CA2-4,DG resistance to ischemic episode at least partially rely on glutamine and glutamate utilization in mitochondria as a source of carbon to tricarboxylic acid cycle. Carbon 169-175 carbonic anhydrase 2 Homo sapiens 35-40 34197074-0 2021 A Spin-Coated Hydrogel Platform Enables Accurate Investigation of Immobilized Individual Single-Walled Carbon Nanotubes. Carbon 103-109 spindlin 1 Homo sapiens 2-6 34124719-1 2021 A series of carbon dots modified by ionic liquids with various anion species (CDs-ILs-X) were facilely synthesized by a one-pot pyrolysis method and subsequent anion exchange processes, where X- represented the anions of hexafluorophosphate (PF6-), bis(trifluorosulfonyl) imide (NTf2-), bis(salicylato) borate (BScB-) and oleate (OL-). Carbon 12-18 nuclear transport factor 2 Homo sapiens 279-283 34138569-3 2021 Intriguingly, the C atom arrangement reveals multiple structure evolution behavior with increased carbon content, from isolated anions in Na4C, tetramers in Na3C2, extended chains in NaC, pentagonal rings in Na2C3, to eventually hexagonal rings in NaC2. Carbon 98-104 X-linked Kx blood group Homo sapiens 183-186 34145762-2 2021 Ascertaining that, metal-organic-framework-derived freestanding, defect-rich, and in situ oxidized Fe-Co-O/Co metal@N-doped carbon (Co@NC) mesoporous nanosheet (mNS) heterostructure on Ni foam (Fe-Co-O/Co@NC-mNS/NF) is developed from the in situ oxidation of micropillar-like heterostructured Fe-Co-O/Co@NC/NF precatalyst. Carbon 124-130 neurofascin Homo sapiens 212-214 34145762-2 2021 Ascertaining that, metal-organic-framework-derived freestanding, defect-rich, and in situ oxidized Fe-Co-O/Co metal@N-doped carbon (Co@NC) mesoporous nanosheet (mNS) heterostructure on Ni foam (Fe-Co-O/Co@NC-mNS/NF) is developed from the in situ oxidation of micropillar-like heterostructured Fe-Co-O/Co@NC/NF precatalyst. Carbon 124-130 neurofascin Homo sapiens 307-309 34207418-0 2021 Direct Pattern Growth of Carbon Nanomaterials by Laser Scribing on Spin-Coated Cu-PI Composite Films and Their Gas Sensor Application. Carbon 25-31 spindlin 1 Homo sapiens 67-71 34081461-3 2021 We carried out single enzyme@MOF nanoparticle (NP) collision experiments using the carbon ultramicroelectrode (CUME), which demonstrated that the catalytic activity of GOx@ZIF-8 NPs was much less than GOx@aZIF-8 NPs. Carbon 83-89 hydroxyacid oxidase 1 Homo sapiens 168-171 34447239-14 2021 The administration of rh-lumican to poly I:C-stimulated HLMs reduced the mRNA levels of CCL2, CCL5, and CXCL10. Carbon 43-44 C-C motif chemokine ligand 5 Homo sapiens 94-98 34447239-14 2021 The administration of rh-lumican to poly I:C-stimulated HLMs reduced the mRNA levels of CCL2, CCL5, and CXCL10. Carbon 43-44 C-X-C motif chemokine ligand 10 Homo sapiens 104-110 34194506-5 2021 Our results showed that compared to CK treatment, SEDI significantly increased the contents of organic carbon (SOC), soil humic acid carbon (HAC), fulvic acid carbon (FAC), and humin C content (HM-C) in the subsurface soil layer by 27.47%, 34.33%, 19.66%, and 31.49%, respectively. Carbon 103-109 cytidine/uridine monophosphate kinase 1 Homo sapiens 36-38 34194506-5 2021 Our results showed that compared to CK treatment, SEDI significantly increased the contents of organic carbon (SOC), soil humic acid carbon (HAC), fulvic acid carbon (FAC), and humin C content (HM-C) in the subsurface soil layer by 27.47%, 34.33%, 19.66%, and 31.49%, respectively. Carbon 133-139 cytidine/uridine monophosphate kinase 1 Homo sapiens 36-38 34141496-8 2021 Compared with the CK treatment, the cumulative organic carbon mineralization rate (Cr) of the S2 and S3 treatment s decreased by 7.77% and 6.05%, respectively; and the C0/SOC decreased by 22.84% and 15.55%, respectively. Carbon 55-61 cytidine/uridine monophosphate kinase 1 Homo sapiens 18-20 34072265-3 2021 The cationic polymers efficiently complexed siRNA into polyplexes, showing a sandwich-like structure with a PAsp(-N=C-PEG) out-layer, a crosslinked PCys interlayer, and a complexing core of siRNA and PAsp(DETA). Carbon 116-117 carboxypeptidase B1 Homo sapiens 108-112 34163736-1 2021 The reactivities of cyclic enones and alpha,beta-unsaturated lactones were characterized by following the kinetics of their reactions with colored carbon-centered reference nucleophiles in DMSO at 20 C. The experimentally determined second-order rate constants k 2 were analyzed with the Mayr-Patz equation, lg k = s N(N + E), to furnish the electrophilicity descriptors E for the Michael acceptors. Carbon 147-153 POZ/BTB and AT hook containing zinc finger 1 Homo sapiens 294-298 35452927-3 2022 Nickel-cobalt sulfide nanoparticles are hydrothermally grown on electrospun carbon nanofibers (CNF@NiCoS-650). Carbon 76-82 NPHS1 adhesion molecule, nephrin Homo sapiens 95-98 35452731-0 2022 Exploration of potential mechanism of interleukin-33 up-regulation caused by 1,4-naphthoquinone black carbon in RAW264.7 cells. Carbon 102-108 interleukin 33 Mus musculus 38-52 35452731-4 2022 In this research, macrophage cell line RAW264.7 was used to explore the potential mechanism of upregulation of IL-33 induced by 1,4-naphthoquinone black carbon (1,4-NQ-BC), and to explore changes of lysosomes and mitochondria during the process. Carbon 153-159 interleukin 33 Mus musculus 111-116 35616264-3 2022 A TiO2 sol-G nanocomposite was prepared and coated on a screen-printed carbon electrode (SPCE) integrated with non-immobilized lactate oxidase (LOx) to produce a novel lactate biosensor with high sensitivity and high storage stability for human blood lactate measurement. Carbon 71-77 lysyl oxidase Homo sapiens 144-147 35181423-17 2022 The various developed 2D-carbon nanomaterials-based electrochemical sensors were applied in pharmaceutical forms, fruits, tap/lake water, beverages, and soils sources. Carbon 25-31 nuclear RNA export factor 1 Homo sapiens 122-125 35617319-8 2022 The calculated distances between the heme oxygen and the dioxin carbon nearest to the oxygen, reflecting the hydroxylating potential of CYP1A2, were higher than in other pCYP1 enzymes. Carbon 64-70 cytochrome P450 family 1 subfamily A member 2 Sus scrofa 136-142 35522997-2 2022 We report the synthesis and operation mode of two all-organic molecular spin-state switches that can be photochemically switched from a diamagnetic (electron paramagnetic resonance (EPR)-silent) to a paramagnetic (EPR-active) form at cryogenic temperatures due to a reversible electrocyclic reaction of its carbon skeleton. Carbon 307-313 spindlin 1 Homo sapiens 72-76 35631853-1 2022 To fabricate N-CQDs hybrid thermo-sensitive polymer (poly-N-CQDs), N-doped carbon quantum dots (N-CQDs) with strong blue fluorescence and poly(N-isopropylacrylamide-co-acrylic acid) (poly(NIPAAm-co-AAc)) copolymer with thermo-sensitivity were synthesized, respectively. Carbon 75-81 glycine-N-acyltransferase Homo sapiens 198-201 35446535-2 2022 Bioinspired by the architecture and multi-functional properties of mangrove roots, this study develops a simple and versatile strategy based on magnetron sputtering and chemical vapor deposition to fabricate a mangrove root-inspired carbon nanotube film (MR-CNTF) as the functional interface in muDMFCs. Carbon 233-239 ciliary neurotrophic factor Homo sapiens 258-262 35065174-2 2022 Bioremediation of RDX is feasible through biostimulation of native microbes with an organic carbon donor but may be less efficient, or not occur at all, in the presence of the common co-contaminants perchlorate and nitrate. Carbon 92-98 radixin Homo sapiens 18-21 35041959-5 2022 Ship emitted single particles contain organic carbon (OC), elemental carbon (EC), metals, sulfate and nitrate. Carbon 59-75 inositol polyphosphate-5-phosphatase D Homo sapiens 0-4 35041959-5 2022 Ship emitted single particles contain organic carbon (OC), elemental carbon (EC), metals, sulfate and nitrate. Carbon 77-79 inositol polyphosphate-5-phosphatase D Homo sapiens 0-4 35041959-7 2022 The relative abundance of OC and EC-related components in ship emitted particles varied and it was likely attributed to the different blending fluids used in the production of low sulfur fuels. Carbon 33-35 inositol polyphosphate-5-phosphatase D Homo sapiens 58-62 35277949-2 2022 Herein, a facile approach is utilized to prepare free-standing 3D cathode substrates comprising nitrogen-doped carbon (N-C) scaffold and metal-organic framework derived interconnected chain-like hollow N-C nanocages, forming a highly porous N-C nanofiber (HP-N-CNF) framework. Carbon 111-117 NPHS1 adhesion molecule, nephrin Homo sapiens 261-264 35499203-0 2022 Bean Pod-Like SbSn/N-Doped Carbon Fibers toward a Binder Free, Free-Standing, and High-Performance Anode for Sodium-Ion Batteries. Carbon 27-33 brain expressed associated with NEDD4 1 Homo sapiens 0-4 35499203-3 2022 Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs). Carbon 213-219 brain expressed associated with NEDD4 1 Homo sapiens 119-123 35499203-3 2022 Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs). Carbon 244-250 brain expressed associated with NEDD4 1 Homo sapiens 119-123 35499203-3 2022 Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs). Carbon 278-284 brain expressed associated with NEDD4 1 Homo sapiens 119-123 35486677-9 2022 Collectively, our studies revealed a role of SDH/complex II in allocating carbon resources for anabolic processes and epigenetic regulation in T cell proliferation and inflammation. Carbon 74-80 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 45-48 35591523-1 2022 We demonstrate a cross-linked, 3D conductive network structure, porous silicon@carbon nanofiber (P-Si@CNF) anode by magnesium thermal reduction (MR) and the electrospinning methods. Carbon 79-85 NPHS1 adhesion molecule, nephrin Homo sapiens 102-105 35468936-8 2022 After carbon source supplementation to the chitinase production media, the average chitinase activity was significantly highest in glycerol supplementation. Carbon 6-12 chitinase-like protein 1 Brassica rapa 83-92 34995622-3 2022 Herein, Cu-coupled Fe/Fe3C covered with carbon layer on carbon felt (Cu-Fe/Fe3C@C), engineered by a hydrothermal reaction followed by the consequent thermal-treatment in N2 atmosphere, as a self-supported integrated cathode were used for an onsite oxygen reduction reaction and a Fenton oxidation reaction. Carbon 40-46 general transcription factor IIE subunit 1 Homo sapiens 72-74 34995622-3 2022 Herein, Cu-coupled Fe/Fe3C covered with carbon layer on carbon felt (Cu-Fe/Fe3C@C), engineered by a hydrothermal reaction followed by the consequent thermal-treatment in N2 atmosphere, as a self-supported integrated cathode were used for an onsite oxygen reduction reaction and a Fenton oxidation reaction. Carbon 56-62 general transcription factor IIE subunit 1 Homo sapiens 19-21 34995622-3 2022 Herein, Cu-coupled Fe/Fe3C covered with carbon layer on carbon felt (Cu-Fe/Fe3C@C), engineered by a hydrothermal reaction followed by the consequent thermal-treatment in N2 atmosphere, as a self-supported integrated cathode were used for an onsite oxygen reduction reaction and a Fenton oxidation reaction. Carbon 56-62 general transcription factor IIE subunit 1 Homo sapiens 72-74 34995622-8 2022 Compared with tradition electrochemical degrade system, the prepared Cu-Fe/Fe3C@C electrode as cathode for practical refractory brewing leachate treatment reveal more efficient decolorization and mineralization, saving 14.3% of electricity. Carbon 80-81 general transcription factor IIE subunit 1 Homo sapiens 72-74 35406024-2 2022 Provitamin A carotenoids are metabolically converted to retinal (beta-apo-15-carotenal) by the enzyme beta-carotene-15,15"-dioxygenase (BCO1) that catalyzes the oxidative cleavage of the central C=C double bond. Carbon 195-196 beta-carotene oxygenase 1 Homo sapiens 136-140 35406024-2 2022 Provitamin A carotenoids are metabolically converted to retinal (beta-apo-15-carotenal) by the enzyme beta-carotene-15,15"-dioxygenase (BCO1) that catalyzes the oxidative cleavage of the central C=C double bond. Carbon 197-198 beta-carotene oxygenase 1 Homo sapiens 136-140 35362241-8 2022 PRACTITIONER POINTS: UASB, SBR, and MBR were adopted to treat low-carbon wastewater using anaerobic digestion process. Carbon 66-72 translocator protein Homo sapiens 36-39 35183903-6 2022 ABCA1-CEC was positively correlated with the concentrations of prebeta-1 particles, triglycerides, small-dense (sd) LDL-C, and LDL-C in both cases and controls. Carbon 119-121 ATP binding cassette subfamily A member 1 Homo sapiens 0-5 35183903-6 2022 ABCA1-CEC was positively correlated with the concentrations of prebeta-1 particles, triglycerides, small-dense (sd) LDL-C, and LDL-C in both cases and controls. Carbon 130-132 ATP binding cassette subfamily A member 1 Homo sapiens 0-5 35232977-8 2022 Finally, we observed that RP5-998N21.4OE can enhance IFIT2- and IFIT3-mediated immune defense responses through activation of signal transducer and activator of transcription 1 (STAT1) signaling pathway in U251 astrocytoma cells under treatment with the viral mimetic polyinosinic: polycytidylic acid (poly I:C). Carbon 309-310 signal transducer and activator of transcription 1 Homo sapiens 126-176 35232977-8 2022 Finally, we observed that RP5-998N21.4OE can enhance IFIT2- and IFIT3-mediated immune defense responses through activation of signal transducer and activator of transcription 1 (STAT1) signaling pathway in U251 astrocytoma cells under treatment with the viral mimetic polyinosinic: polycytidylic acid (poly I:C). Carbon 309-310 signal transducer and activator of transcription 1 Homo sapiens 178-183 35115491-0 2022 Carbon-coated MoS1.5Te0.5 nanocables for efficient sodium-ion storage in non-aqueous dual-ion batteries. Carbon 0-6 MOS proto-oncogene, serine/threonine kinase Homo sapiens 14-17 35103399-1 2022 The spin polarization of carbon nanomaterials is crucial to design spintronic devices. Carbon 25-31 spindlin 1 Homo sapiens 4-8 34624079-4 2022 We focused on serine hydroxymethyltransferase 2 (SHMT2), a key enzyme in one-carbon metabolism. Carbon 77-83 serine hydroxymethyltransferase 2 Homo sapiens 14-47 34624079-4 2022 We focused on serine hydroxymethyltransferase 2 (SHMT2), a key enzyme in one-carbon metabolism. Carbon 77-83 serine hydroxymethyltransferase 2 Homo sapiens 49-54 35078998-4 2022 Cu-C bond formation stems from spontaneous charge transfer (CT) between Cu2(L)(py)4 and (Li+@C60)(NTf2-) by removing the two-terminal py molecules, yielding triplet ground state (Cu2(L)(py)2)+(Li+@C60 -), evidenced by absorption and electron paramagnetic resonance (EPR) spectra, magnetic properties and quantum chemical calculations. Carbon 3-4 nuclear transport factor 2 Homo sapiens 98-102 35163908-4 2022 The Mo species, moreover, led to a decrease in the (C15 + C17)/(C16 + C18) ratio, which is beneficial from the viewpoint of carbon atom economy. Carbon 124-130 placenta associated 8 Homo sapiens 52-55 34951436-1 2022 We report the first synthesis and computational study of Sc3N@C78(CF2) - an analog of the previously reported Sc3N@C80(CF2) with a less common carbon cage whose chemical properties presently remain far less studied. Carbon 143-149 ATPase H+ transporting accessory protein 1 Homo sapiens 66-69 34951436-3 2022 Even though the less symmetric D3h(5)-C78 carbon cage offers far broader opportunities for isomerism than Ih-C80, CF2 addition to Sc3N@C78 proceeds regioselectively, similarly to other common fullerene reactions. Carbon 42-48 ATPase H+ transporting accessory protein 1 Homo sapiens 114-117 34996872-5 2022 Moreover, the finding that the Chlamydomonas starch-deficient mutant sta6 displayed disproportionate TOR activity and high levels of most amino acids, particularly Gln, further connected carbon assimilation and amino acids to TOR signaling. Carbon 187-193 uncharacterized protein Chlamydomonas reinhardtii 69-73 35046699-1 2022 Objective: The aim of this study is to assess the relationship between the single-nucleotide polymorphism (SNP) in the one-carbon metabolism pathway (MTR rs1805087; MTHFR rs1801133; ALDH1L1 rs2002287, rs2276731; DNMT1 rs16999593, rs2228611; DNMT3B rs2424908) and the risk of female breast cancer (BC) in a Chinese population. Carbon 123-129 methylenetetrahydrofolate reductase Homo sapiens 165-170 35046699-1 2022 Objective: The aim of this study is to assess the relationship between the single-nucleotide polymorphism (SNP) in the one-carbon metabolism pathway (MTR rs1805087; MTHFR rs1801133; ALDH1L1 rs2002287, rs2276731; DNMT1 rs16999593, rs2228611; DNMT3B rs2424908) and the risk of female breast cancer (BC) in a Chinese population. Carbon 123-129 DNA methyltransferase 1 Homo sapiens 212-217 34989879-2 2022 In this study, we introduced a novel Ti3C2Tx (MXene) aerogels (denoted as MXA) composite gold nano-particles (AuNPs)-modified disposable carbon fiber paper (CFP) electrode for the label-free and sensitive detection of miRNA-155. Carbon 137-143 microRNA 155 Homo sapiens 218-227