PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
15334549-3	2004	In this study, we cloned genomic breakpoints of the MLL and CBP genes in the t(11;16) in the SN-1 cell line and in five patients with therapy-related leukemia, all of whom had received topo II inhibitors for previous tumors.	trioctyl phosphine oxide	185-189	lysine methyltransferase 2A	Homo sapiens	52-55
16287277-1	2005	A simple one-pot method has been used to prepare uniform single-crystalline CoP nanowires with a high aspect ratio by the thermal-decomposition reaction of cobalt(II) acetylacetone with long-chain alkylphosphonic acid in the presence of hexadecylamine (HDA) and trioctylphosphine oxide (TOPO) at high temperature.	trioctyl phosphine oxide	262-285	caspase recruitment domain family member 16	Homo sapiens	76-79
16287277-1	2005	A simple one-pot method has been used to prepare uniform single-crystalline CoP nanowires with a high aspect ratio by the thermal-decomposition reaction of cobalt(II) acetylacetone with long-chain alkylphosphonic acid in the presence of hexadecylamine (HDA) and trioctylphosphine oxide (TOPO) at high temperature.	trioctyl phosphine oxide	287-291	caspase recruitment domain family member 16	Homo sapiens	76-79
15334549-3	2004	In this study, we cloned genomic breakpoints of the MLL and CBP genes in the t(11;16) in the SN-1 cell line and in five patients with therapy-related leukemia, all of whom had received topo II inhibitors for previous tumors.	trioctyl phosphine oxide	185-189	CREB binding protein	Homo sapiens	60-63
11327387-6	2001	The allelic frequency of HLA-DQB1*0402 was significantly higher in anti-topo I positive patients (28.6%) than in anti-topo I negative patients (1.5%, P < 0.001) or healthy controls (0.8%, P<0.001).	trioctyl phosphine oxide	72-76	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	25-33
11569824-2	2001	In the pH range of 7.54-8.14, the interaction of the binary complex of Eu(III)/CTC in the presence of trioctyl phosphine oxide (TOPO) occurs at the H20/CCl4 interface, resulting in greatly enhanced TIR-RLS signals with the maximum peak located at 340 nm.	trioctyl phosphine oxide	102-126	C-C motif chemokine ligand 4	Homo sapiens	152-156
11469465-4	2001	HLA-DR 67FLEDR71, especially 38V-67FLEDR71 sequence (carried on DRB5*0102 in linkage disequilibrium with DRB1*1502, DRB1*0802, DRBI*1101), showed the strongest association with anti-topo I response (46% vs 16% in controls; Pcorr = 0.001), and 38L-67FLEDR71 group alleles were not associated with anti-topo I response.	trioctyl phosphine oxide	182-186	major histocompatibility complex, class II, DQ beta 1	Homo sapiens	0-3
11469465-4	2001	HLA-DR 67FLEDR71, especially 38V-67FLEDR71 sequence (carried on DRB5*0102 in linkage disequilibrium with DRB1*1502, DRB1*0802, DRBI*1101), showed the strongest association with anti-topo I response (46% vs 16% in controls; Pcorr = 0.001), and 38L-67FLEDR71 group alleles were not associated with anti-topo I response.	trioctyl phosphine oxide	182-186	major histocompatibility complex, class II, DR beta 1	Homo sapiens	105-109
11469465-4	2001	HLA-DR 67FLEDR71, especially 38V-67FLEDR71 sequence (carried on DRB5*0102 in linkage disequilibrium with DRB1*1502, DRB1*0802, DRBI*1101), showed the strongest association with anti-topo I response (46% vs 16% in controls; Pcorr = 0.001), and 38L-67FLEDR71 group alleles were not associated with anti-topo I response.	trioctyl phosphine oxide	182-186	major histocompatibility complex, class II, DR beta 1	Homo sapiens	116-120
34793676-1	2021	The process of formation of a Langmuir-Schaefer (LS) matrix based on a mixed monolayer of arachidic acid (AA) and 8 nm CdSe/CdS/ZnS quantum dots (QDs) stabilized by molecules of trioctylphosphine oxide (TOPO) was investigated.	trioctyl phosphine oxide	178-201	CDP-diacylglycerol synthase 1	Homo sapiens	124-127
34793676-1	2021	The process of formation of a Langmuir-Schaefer (LS) matrix based on a mixed monolayer of arachidic acid (AA) and 8 nm CdSe/CdS/ZnS quantum dots (QDs) stabilized by molecules of trioctylphosphine oxide (TOPO) was investigated.	trioctyl phosphine oxide	203-207	CDP-diacylglycerol synthase 1	Homo sapiens	124-127
22305542-4	2012	The complex 1 shows high inhibitory activity against Topo I at a very low concentration (15 muM), suggesting that complex 1 is an efficient catalytic inhibitor of human Topo I and further validated by molecular docking studies.	trioctyl phosphine oxide	53-57	latexin	Homo sapiens	92-95
32390296-3	2020	For a conventional reaction of cadmium oleate (Cd(OA)2 ) and sulfur (S) in 1-octadecene (ODE), we show that after the formation of the PC in the pre-nucleation stage, the addition of tri-n-octylphosphine oxide (TOPO) facilitates the production of small-size QDs.	trioctyl phosphine oxide	183-209	OA2	Homo sapiens	47-54
32390296-3	2020	For a conventional reaction of cadmium oleate (Cd(OA)2 ) and sulfur (S) in 1-octadecene (ODE), we show that after the formation of the PC in the pre-nucleation stage, the addition of tri-n-octylphosphine oxide (TOPO) facilitates the production of small-size QDs.	trioctyl phosphine oxide	211-215	OA2	Homo sapiens	47-54
31710370-7	2019	The mean refractive cylinder changed from -1.53 +- 0.70 D preoperatively to -0.22 +- 0.33 D at 6 months postoperatively in the SMILE group, -1.19 +- 1.23 to -0.19 +- 0.30 D in the TOPO group, and -1.77 +- 1.65 to -0.33 +- 0.36 D in the WFG group.	trioctyl phosphine oxide	180-184	transmembrane O-mannosyltransferase targeting cadherins 3	Homo sapiens	127-132
34652866-2	2022	In this study, it is demonstrated that the 4-phosphoryl pyrazolones, HL2 -HL4 , in the presence of the typical industrial organophosphorus co-ligands tributylphosphine oxide (TBPO), tributylphosphate (TBP) and trioctylphosphine oxide (TOPO), are able to selectively recognise and extract lithium ions from aqueous solution.	trioctyl phosphine oxide	210-233	intelectin 2	Homo sapiens	69-72
34652866-2	2022	In this study, it is demonstrated that the 4-phosphoryl pyrazolones, HL2 -HL4 , in the presence of the typical industrial organophosphorus co-ligands tributylphosphine oxide (TBPO), tributylphosphate (TBP) and trioctylphosphine oxide (TOPO), are able to selectively recognise and extract lithium ions from aqueous solution.	trioctyl phosphine oxide	235-239	intelectin 2	Homo sapiens	69-72
24981677-1	2014	The present paper is focused on solvent extraction of hazardous Cd(II) from acidic chloride media by Cyanex 921, a new extractant mixed with 10% (v/v) TBP in xylene.	trioctyl phosphine oxide	101-111	TATA-box binding protein	Homo sapiens	151-154
24225581-2	2013	A significant increase of the extraction efficiency was found on the addition of NTf2(-) based ILs when using neutral extractant tri-octylphosphine oxide (TOPO), and the extraction efficiency kept high at both nearly neutral and high acidity.	trioctyl phosphine oxide	129-153	nuclear transport factor 2	Homo sapiens	81-85
24225581-2	2013	A significant increase of the extraction efficiency was found on the addition of NTf2(-) based ILs when using neutral extractant tri-octylphosphine oxide (TOPO), and the extraction efficiency kept high at both nearly neutral and high acidity.	trioctyl phosphine oxide	155-159	nuclear transport factor 2	Homo sapiens	81-85
17601807-4	2007	To understand this discrepancy, pepD was cloned into an Escherichia coli expression vector (pBAD-TOPO derivative) to generate the recombinant plasmids pBAD-pepD and pBAD-pepD-His (note that His in the plasmid designation stands for a polyhistidine coding region).	trioctyl phosphine oxide	97-101	C69 family dipeptidase	Bifidobacterium longum NCC2705	32-36