PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 3219332-8 1988 The binding and transfer vs chain length profiles were quite similar for C(16)Pyr(x)PC and C(16)Pyr(x)PI species, suggesting that the sn-2 acyl chains of PI and PC share a common binding site in PI-TP. neotetrazolium 198-200 solute carrier family 38 member 5 Bos taurus 134-138 3179276-4 1988 The sugar puckering of Tp- is dominated by the 2E conformer, but in -pT it is in 4E; except for the conformer around C5"-O5" bond, the 6-4 isomer is very similar to those of cis-syn and trans-syn conformation. neotetrazolium 23-25 synemin Homo sapiens 192-195 3179276-9 1988 While the trans-syn photodimer has two structural isomers, only one [C6(of Tp-)-R] was produced by the UV irradiation and studied. neotetrazolium 75-77 synemin Homo sapiens 16-19 6798728-1 1981 The paper deals with the influence of 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2.2-dichloroethane (o,p"-DDD, chloditane) on NADPH-dependent reduction of cytochrome c, ferricyanide, 2,6-dichlorophenolindophenol and neotetrazolium; 156 and 312 mumol o,p"-DDD was added to the dog adrenal mitochondrial and microsomal suspension. neotetrazolium 211-225 cytochrome c, somatic Canis lupus familiaris 150-162 3179276-4 1988 The sugar puckering of Tp- is dominated by the 2E conformer, but in -pT it is in 4E; except for the conformer around C5"-O5" bond, the 6-4 isomer is very similar to those of cis-syn and trans-syn conformation. neotetrazolium 23-25 synemin Homo sapiens 178-181 6186695-1 1983 When non-malignant cells were reacted for glucose-6-phosphate dehydrogenase activity, with neotetrazolium chloride as the indicator of the activity, oxygen competed with the neotetrazolium and nullified the reaction. neotetrazolium 91-114 glucose-6-phosphate dehydrogenase Homo sapiens 42-75 6186695-1 1983 When non-malignant cells were reacted for glucose-6-phosphate dehydrogenase activity, with neotetrazolium chloride as the indicator of the activity, oxygen competed with the neotetrazolium and nullified the reaction. neotetrazolium 91-105 glucose-6-phosphate dehydrogenase Homo sapiens 42-75 3111786-5 1987 The integrated insulin response to a 75g OGTT in the TP group increased by 48.3% at 6 months compared with an increase of 23.4% for the same period in the IUD group. neotetrazolium 53-55 insulin Homo sapiens 15-22 29552824-1 2018 To explore the effects and molecular mechanisms of triptolide(TP)on improving podocyte epithelial-mesenchymal transition(EMT)induced by high dose of D-glucose(HG), the immortalized podocytes of mice in vitro were divided into the normal group(N), the high dose of D-glucose group(HG), the low dose of TP group(L-TP), the high dose of TP group(H-TP)and the mannitol group(MNT), and treated by the different measures respectively. neotetrazolium 62-64 IL2 inducible T cell kinase Mus musculus 121-124 32176847-5 2020 TP-008 has excellent cellular potency and strongly abrogates phosphorylation of the substrate SMAD2 (mothers against decapentaplegic homologue 2). neotetrazolium 0-2 SMAD family member 2 Homo sapiens 94-99 30903412-12 2020 The TP group had a lower lung wet to dry weight ratio, lung injury score, and MPO, TNF-, and IL-8 concentrations than the MO group (P < 0.05). neotetrazolium 4-6 myeloperoxidase Sus scrofa 78-81 30903412-12 2020 The TP group had a lower lung wet to dry weight ratio, lung injury score, and MPO, TNF-, and IL-8 concentrations than the MO group (P < 0.05). neotetrazolium 4-6 tumor necrosis factor Sus scrofa 83-86 30903412-12 2020 The TP group had a lower lung wet to dry weight ratio, lung injury score, and MPO, TNF-, and IL-8 concentrations than the MO group (P < 0.05). neotetrazolium 4-6 C-X-C motif chemokine ligand 8 Sus scrofa 93-97 30641088-4 2019 The molecular markers of cardiac hypertrophy along with androgen receptor (AR) and PKCdelta, were increased in the Maternal-TP group. neotetrazolium 124-126 androgen receptor Rattus norvegicus 56-73 30641088-4 2019 The molecular markers of cardiac hypertrophy along with androgen receptor (AR) and PKCdelta, were increased in the Maternal-TP group. neotetrazolium 124-126 androgen receptor Rattus norvegicus 75-77 30306335-11 2019 However, only NaF-gel2 and NaF-TP induced remineralization. neotetrazolium 31-33 C-X-C motif chemokine ligand 8 Homo sapiens 27-30 31424649-11 2019 Moreover, the positive expression rate of P-gp was also different among the 3 groups, and it was increased in the TP group, while it was decreased in the RH and rAd-p53 + TP group (p<0.05). neotetrazolium 114-116 phosphoglycolate phosphatase Homo sapiens 42-46 31424649-11 2019 Moreover, the positive expression rate of P-gp was also different among the 3 groups, and it was increased in the TP group, while it was decreased in the RH and rAd-p53 + TP group (p<0.05). neotetrazolium 171-173 phosphoglycolate phosphatase Homo sapiens 42-46 30277822-6 2019 Further deletion of E prostanoid receptor type 3 (EP3-/-) removed the PGF2alpha-evoked contraction that remained in some TP-/- arteries and added to the effect of TP-/- on the elevation in blood pressure evoked by the prostanoid under in vivo conditions. neotetrazolium 121-123 prostaglandin E receptor 3 (subtype EP3) Mus musculus 20-57 29565447-21 2018 Univariate and multivariate analyses revealed that age, CA125, interstitial IL-6 expression and cytoreduction satisfaction were closely related to the sensitivity of the TP (docetaxel plus cisplatin or carbopatin) regimen in ovarian cancer (P<0.05). neotetrazolium 170-172 mucin 16, cell surface associated Homo sapiens 56-61 29565447-21 2018 Univariate and multivariate analyses revealed that age, CA125, interstitial IL-6 expression and cytoreduction satisfaction were closely related to the sensitivity of the TP (docetaxel plus cisplatin or carbopatin) regimen in ovarian cancer (P<0.05). neotetrazolium 170-172 interleukin 6 Homo sapiens 76-80 29516720-3 2018 In this work, a novel two-photon fluorescent probe TP-HNO was designed and synthesized based on 6-hydroxyl-quinonline-2-benzothiazole derivatives through introducing 2-(diphenylphosphino)benzoate as the ideal HNO recognition unit, which demonstrated the merits of outstanding selectivity, excellent sensitivity (DL 0.19 muM) and rapid response (20 min). neotetrazolium 51-53 latexin Homo sapiens 320-323 27349952-7 2017 Despite higher RBV-TP levels, individuals with variant ITPA phenotypes had less anemia. neotetrazolium 19-21 inosine triphosphatase Homo sapiens 55-59 29234377-1 2017 To investigate the potential role of nuclear factor erythroid 2-related factor 2 (Nrf2) in licorice ethanol extract (LEE) against triptolide- (TP-) induced hepatotoxicity, HepG2 cells were exposed to LEE (30, 60, and 90 mg L-1) for 12 h and then treated with TP (50 nM) for 24 h. Besides, an acute liver injury model was established in ICR mice by a single dose of TP (1.0 mg kg-1, i.p.). neotetrazolium 143-145 NFE2 like bZIP transcription factor 2 Homo sapiens 82-86 29234377-6 2017 Furthermore, the decreased level of Nrf2 in the TP-treated group was observed. neotetrazolium 48-50 NFE2 like bZIP transcription factor 2 Homo sapiens 36-40 28681218-1 2017 The aim of this study is to evaluate the outcome and safety of the multidisciplinary strategy using cisplatin plus dose-dense paclitaxel (dose-dense TP) before and after radical hysterectomy (RH) for stage IB2, IIA2, or IIB patients with cervical cancer. neotetrazolium 149-151 mitogen-activated protein kinase 8 interacting protein 2 Homo sapiens 206-209 28414431-1 2017 Orange Tp*WSCl2 has been synthesized from the reactions of Tp*WOCl2 with boron sulfide in refluxing toluene or Tp*WS2Cl with PPh3 in dichloromethane at room temperature. neotetrazolium 7-9 caveolin 1 Homo sapiens 125-129 27776874-2 2017 Pilot scale study showed that when the influent COD, TP and TSS were 73.0, 1.40 and 24.6mgL-1, the effluent COD, TP and TSS were 48.9, 0.32, 7.78mgL-1 for System-A with the ozone and Fe2+ dosage of 25mgL-1 and 0.08mmolL-1, and 60.2, 1.16, 6.44mgL-1 for System-B with the ozone dosage of 25mgL-1. neotetrazolium 53-55 LLGL scribble cell polarity complex component 1 Homo sapiens 88-93 27831827-4 2016 We identified 3 conserved Sp/Tp residues that are located in the N-terminal, most conserved part, of SPAT-1/Bora. neotetrazolium 29-31 Protein aurora borealis Caenorhabditis elegans 101-107 27349952-9 2017 This finding of higher RBV-TP concentrations in RBCs in ITPA variants was unexpected given that ITPA activity-deficient individuals have a reduced likelihood of RBV-induced anemia. neotetrazolium 27-29 inosine triphosphatase Homo sapiens 56-60 27349952-9 2017 This finding of higher RBV-TP concentrations in RBCs in ITPA variants was unexpected given that ITPA activity-deficient individuals have a reduced likelihood of RBV-induced anemia. neotetrazolium 27-29 inosine triphosphatase Homo sapiens 96-100 27195913-4 2016 The present study reported that phosphorylated caspase-8 at tyrosine 380 (p-Casp8) was characterized as a biomarker of chemoresistance to TP regimen (cisplatin and paclitaxel) in patients with resectable lung adenocarcinoma with significantly poorer 5-year disease-free survival (DFS) and overall survival (OS). neotetrazolium 138-140 caspase 8 Homo sapiens 47-72 29964668-6 2016 In the dry season, average concentrations of TN and TP were 4.25 mg L-1 and 0.11 mg L-1, respectively, compared to the corresponding values of 3.15 mg L-1 and 0.09 mg L-1 in wet season. neotetrazolium 52-54 immunoglobulin kappa variable 1-16 Homo sapiens 68-80 29964668-6 2016 In the dry season, average concentrations of TN and TP were 4.25 mg L-1 and 0.11 mg L-1, respectively, compared to the corresponding values of 3.15 mg L-1 and 0.09 mg L-1 in wet season. neotetrazolium 52-54 immunoglobulin kappa variable 1-16 Homo sapiens 68-71 29964668-6 2016 In the dry season, average concentrations of TN and TP were 4.25 mg L-1 and 0.11 mg L-1, respectively, compared to the corresponding values of 3.15 mg L-1 and 0.09 mg L-1 in wet season. neotetrazolium 52-54 immunoglobulin kappa variable 1-16 Homo sapiens 84-87 29964668-6 2016 In the dry season, average concentrations of TN and TP were 4.25 mg L-1 and 0.11 mg L-1, respectively, compared to the corresponding values of 3.15 mg L-1 and 0.09 mg L-1 in wet season. neotetrazolium 52-54 immunoglobulin kappa variable 1-16 Homo sapiens 84-87 27334096-2 2016 Exposure of Tp(Ph,Me)NiCH2Ph (1a) and Tp(Ph,Me)NiCH2Si(CH3)3 (1b) to CS2 resulted in formation of the insertion products Tp(Ph,Me)Ni(eta(2)-CS2)CH2Ph (2a) and Tp(Ph,Me)Ni(eta(2)-CS2)CH2Si(CH3)3 (2b) in moderate yields. neotetrazolium 12-14 chorionic somatomammotropin hormone 2 Homo sapiens 69-72 27334096-2 2016 Exposure of Tp(Ph,Me)NiCH2Ph (1a) and Tp(Ph,Me)NiCH2Si(CH3)3 (1b) to CS2 resulted in formation of the insertion products Tp(Ph,Me)Ni(eta(2)-CS2)CH2Ph (2a) and Tp(Ph,Me)Ni(eta(2)-CS2)CH2Si(CH3)3 (2b) in moderate yields. neotetrazolium 12-14 chorionic somatomammotropin hormone 2 Homo sapiens 140-143 27334096-2 2016 Exposure of Tp(Ph,Me)NiCH2Ph (1a) and Tp(Ph,Me)NiCH2Si(CH3)3 (1b) to CS2 resulted in formation of the insertion products Tp(Ph,Me)Ni(eta(2)-CS2)CH2Ph (2a) and Tp(Ph,Me)Ni(eta(2)-CS2)CH2Si(CH3)3 (2b) in moderate yields. neotetrazolium 12-14 chorionic somatomammotropin hormone 2 Homo sapiens 140-143 27195913-4 2016 The present study reported that phosphorylated caspase-8 at tyrosine 380 (p-Casp8) was characterized as a biomarker of chemoresistance to TP regimen (cisplatin and paclitaxel) in patients with resectable lung adenocarcinoma with significantly poorer 5-year disease-free survival (DFS) and overall survival (OS). neotetrazolium 138-140 caspase 8 Homo sapiens 76-81 26589827-9 2016 The activities of glutathione peroxidase (GPx) and superoxide dismutase (SOD) were higher and the concentration of malondialdehyde (MDA) was lower in the broilers fed 5 % TP than those of the broilers fed other diets at 28 days of age. neotetrazolium 171-173 glutathione peroxidase Solanum lycopersicum 18-40 29964716-7 2016 During the period of monitoring, the pCO2 and pCH4 in surface water were significantly correlated with pH, DO, chlorophyll a, TP, surface water temperature and water level. neotetrazolium 126-128 tRNA splicing endonuclease subunit 54 Homo sapiens 46-50 26589827-9 2016 The activities of glutathione peroxidase (GPx) and superoxide dismutase (SOD) were higher and the concentration of malondialdehyde (MDA) was lower in the broilers fed 5 % TP than those of the broilers fed other diets at 28 days of age. neotetrazolium 171-173 glutathione peroxidase Solanum lycopersicum 42-45 26387142-8 2015 In the combined TH/TP/HP treatment group, in multivariate analysis, higher expression of PD1, MHC2, and STAT1 were linked with pCRB, and higher PDL1, MHC1, or IF-I to lower pCRB. neotetrazolium 19-21 programmed cell death 1 Homo sapiens 89-92 29733157-7 2016 When TN exceeded 1.298 mg L-1 or TP exceeded 0.065 mg L-1(i.e. positive response threshold), even tolerant taxa would be influenced and the whole assemblage would be changed significantly. neotetrazolium 33-35 immunoglobulin kappa variable 1-16 Homo sapiens 54-57 26556866-5 2015 Elevated levels of two different CRNDE transcripts were a negative prognostic factor; they increased the risk of death and recurrence in the group of patients treated with TP, but not PC (DNA-damaging agents only). neotetrazolium 172-174 colorectal neoplasia differentially expressed Homo sapiens 33-38 26387142-8 2015 In the combined TH/TP/HP treatment group, in multivariate analysis, higher expression of PD1, MHC2, and STAT1 were linked with pCRB, and higher PDL1, MHC1, or IF-I to lower pCRB. neotetrazolium 19-21 signal transducer and activator of transcription 1 Homo sapiens 104-109 26387142-8 2015 In the combined TH/TP/HP treatment group, in multivariate analysis, higher expression of PD1, MHC2, and STAT1 were linked with pCRB, and higher PDL1, MHC1, or IF-I to lower pCRB. neotetrazolium 19-21 CD274 molecule Homo sapiens 144-148 26809410-1 2015 Tapentadol(TP)is a new strong opioid analgesicthat has both m-opioid receptor(MOR)effects and norepinephrine reuptake inhibitor(NRI)effects. neotetrazolium 11-13 opioid receptor mu 1 Homo sapiens 78-81 26248960-14 2015 Immunoblot analysis showed a significant decrease in phosphorylated Akt levels after treatment with T or T + P in nonbasal cells but not in basal cells. neotetrazolium 105-110 AKT serine/threonine kinase 1 Homo sapiens 68-71 26344782-1 2015 Dinitrogen complexes of the type Tp(R,R)Cr-N2-CrTp(R,R) are not the most labile precursors for Cr(i) chemistry, as they are sterically protected from obligatory associative ligand substitution. neotetrazolium 33-35 calreticulin Homo sapiens 46-50 25988234-3 2015 The maximum NO conversion over the Cr-HP(3)/TP catalyst reached 71.4% at 280 C. The catalysts were characterized by powder X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), temperature-programmed reduction of H2 (H2-TPR), temperature-programmed desorption (TPD) and diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) techniques. neotetrazolium 44-46 translocated promoter region, nuclear basket protein Homo sapiens 320-323 26095956-1 2015 The stable cationic iridacyclopentenylidene [Tp(Me2)Ir(=CHC(Me)=C(Me)CH2(NCMe)]PF6 (A; Tp(Me2)=hydrotris(3,5-dimethylpyrazolyl)borate) has been obtained by alpha-hydride abstraction from the iridacyclopent-2-ene [Tp(Me2)Ir(CH2C(Me)=C(Me)CH2)(NCMe)]. neotetrazolium 45-47 sperm associated antigen 17 Homo sapiens 79-82 26095956-1 2015 The stable cationic iridacyclopentenylidene [Tp(Me2)Ir(=CHC(Me)=C(Me)CH2(NCMe)]PF6 (A; Tp(Me2)=hydrotris(3,5-dimethylpyrazolyl)borate) has been obtained by alpha-hydride abstraction from the iridacyclopent-2-ene [Tp(Me2)Ir(CH2C(Me)=C(Me)CH2)(NCMe)]. neotetrazolium 87-89 sperm associated antigen 17 Homo sapiens 79-82 26095956-1 2015 The stable cationic iridacyclopentenylidene [Tp(Me2)Ir(=CHC(Me)=C(Me)CH2(NCMe)]PF6 (A; Tp(Me2)=hydrotris(3,5-dimethylpyrazolyl)borate) has been obtained by alpha-hydride abstraction from the iridacyclopent-2-ene [Tp(Me2)Ir(CH2C(Me)=C(Me)CH2)(NCMe)]. neotetrazolium 87-89 sperm associated antigen 17 Homo sapiens 79-82 26095956-3 2015 The coordination of an extra molecule of acetonitrile to the iridium center initiates the reversible isomerization of the chelating carbon chain of A to the monodentate butadienyl ligand of complex [Tp(Me2)Ir(CH=C(Me)C(Me)=CH2)(NCMe)2]PF6, which is capable to engage in a water-promoted C-C coupling with the MeCN co-ligands. neotetrazolium 199-201 sperm associated antigen 17 Homo sapiens 235-238 26148543-4 2015 The availability of the acidic alpha-proton of the acac ligand was tested by the treatment of complex with Br2 and Cu(NO3)2 rendering the substitution complexes [Tp(3-Br,Me2)Ir(3-Br-acac)Br] () and [Tp(Me2)Ir(3-NO2-acac)(C2H5)] () in good yields. neotetrazolium 162-164 malic enzyme 2 Homo sapiens 170-173 26148543-4 2015 The availability of the acidic alpha-proton of the acac ligand was tested by the treatment of complex with Br2 and Cu(NO3)2 rendering the substitution complexes [Tp(3-Br,Me2)Ir(3-Br-acac)Br] () and [Tp(Me2)Ir(3-NO2-acac)(C2H5)] () in good yields. neotetrazolium 162-164 malic enzyme 2 Homo sapiens 202-205 25242657-3 2014 The introduction of TeO(2) as a third glass former to the glass network causes the structural transformation from TeO(3) (tp) to TeO(4) (tbp) which contributes to the changes in conductivity. neotetrazolium 122-125 TATA-box binding protein Homo sapiens 137-140 25816284-11 2015 Overexpression of miR-206 increased reactive oxygen species (ROS) levels in vitro and in vivo, whereas miR-206 silencing attenuated irradiation- or A-TP-induced ROS. neotetrazolium 150-152 microRNA 206 Canis lupus familiaris 103-110 25538206-10 2015 E and TP/CDP were associated with a higher risk of recurrent hypoglycemia episodes (unadjusted hazard ratio: 6.18 ((95% CI: 1.54-24.8); P=0.010) for E vs DP and 9.51 ((95% CI: 1.85-48.8); P=0.007) for TP/CDP vs DP. neotetrazolium 6-8 cut like homeobox 1 Homo sapiens 204-207 25538206-10 2015 E and TP/CDP were associated with a higher risk of recurrent hypoglycemia episodes (unadjusted hazard ratio: 6.18 ((95% CI: 1.54-24.8); P=0.010) for E vs DP and 9.51 ((95% CI: 1.85-48.8); P=0.007) for TP/CDP vs DP. neotetrazolium 201-203 cut like homeobox 1 Homo sapiens 9-12 25341014-3 2014 In contrast to [(Tp(Me,Me))Ni-SAr] analogues that adopt a sawhorse conformation, the ortho-disubstituted complexes show enhanced trigonal and Ni-S-Ar bending, reflecting the size of the 3-pyrazole substituents. neotetrazolium 17-19 sarcosine dehydrogenase Homo sapiens 30-33 24864245-7 2014 These results highlight the importance of the hydrophobic C-6 linker in THP polymers in forming compact nanostructures with pDNA, which might lead to efficient uptake and internalization of the complexes; however, the projected TP polymers offer an advantage of their rapid and economical one-step synthesis. neotetrazolium 228-230 complement C6 Homo sapiens 58-61 22200727-9 2012 Of note, both the positive expression of NF-kappaBp65 (P<0.01 vs. the T and P groups) and p-ERK1/2 (P<0.05 vs. the P group) was lowest in the TP group. neotetrazolium 148-150 mitogen activated protein kinase 3 Rattus norvegicus 95-101 24173213-8 2014 Cellular PPIase Pin1 binds specifically to phosphoserine- or phosphothreonine-proline (pS/T-P) motifs in target proteins. neotetrazolium 90-93 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens 9-20 24048894-10 2013 T+P also blocked the induction of IL-6 to prevent the Th17 response, attenuated the expression of the costimulatory molecule CD86 on myeloid dendritic cells (DCs), and reduced the number of DCs carrying OVA in the lung and mediastinal lymph nodes. neotetrazolium 0-3 interleukin 6 Mus musculus 34-38 24048894-10 2013 T+P also blocked the induction of IL-6 to prevent the Th17 response, attenuated the expression of the costimulatory molecule CD86 on myeloid dendritic cells (DCs), and reduced the number of DCs carrying OVA in the lung and mediastinal lymph nodes. neotetrazolium 0-3 CD86 antigen Mus musculus 125-129 23504554-5 2013 The gene-gene interaction of miR-34b/c rs4938723 and TP-53 Arg72-Pro showed that the combined genotypes of rs4938723CT/CC and TP-53CG/CC increased the risk of NPC (rs4938723CT/CC + TP-53CG/CC vs. rs4938723 TT+TP-53 CG/CC: OR=1.58, 95 % CI 1.04-2.42, p=0.03). neotetrazolium 53-55 microRNA 34b Homo sapiens 29-36 23504554-5 2013 The gene-gene interaction of miR-34b/c rs4938723 and TP-53 Arg72-Pro showed that the combined genotypes of rs4938723CT/CC and TP-53CG/CC increased the risk of NPC (rs4938723CT/CC + TP-53CG/CC vs. rs4938723 TT+TP-53 CG/CC: OR=1.58, 95 % CI 1.04-2.42, p=0.03). neotetrazolium 53-55 tumor protein p53 Homo sapiens 126-131 23401098-0 2013 Reactivity studies of iridium pyridylidenes [Tp(Me2)Ir(C(6)H(5))(2)(C(CH)(3)C(R)NH] (R=H, Me, Ph). neotetrazolium 45-47 malic enzyme 2 Homo sapiens 48-51 22958397-6 2012 The cells transfected with TPE (0.5:1:160) exhibited the highest enhancement of tyrosinase enzyme activity of 11.82-, 7.67-, 5.07-, and 6.29-folds of control, P, PE, and TP (0.5:1) and melanin production of 13.03-, 8.46-, 5.36-, and 6.58-folds of control, P, PE, and TP (0.5:1), respectively. neotetrazolium 27-29 tyrosinase Homo sapiens 80-90 22958397-6 2012 The cells transfected with TPE (0.5:1:160) exhibited the highest enhancement of tyrosinase enzyme activity of 11.82-, 7.67-, 5.07-, and 6.29-folds of control, P, PE, and TP (0.5:1) and melanin production of 13.03-, 8.46-, 5.36-, and 6.58-folds of control, P, PE, and TP (0.5:1), respectively. neotetrazolium 170-172 tyrosinase Homo sapiens 80-90 26588967-2 2012 This work presents a detailed analysis of the physical origin of the zero-field splittings (ZFSs) in a series of high-spin (S = 1) nickel(II) scorpionate complexes Tp*NiX (Tp* = hydrotris(3,5-dimethylpyrazole)borate, X = Cl, Br, I) using quantum chemical approaches. neotetrazolium 164-166 BCL2 interacting protein 3 like Homo sapiens 167-170 24366160-0 2014 A DFT study on structures, frontier molecular orbitals and UV-vis spectra of RuX(PPh3)(NHCPh2)L (X=Tp and Cp; L=Cl and N3). neotetrazolium 99-101 protein phosphatase 4 catalytic subunit Homo sapiens 81-85 24366160-1 2014 Geometry optimization for RuX(PPh3)(NHCPh2)(L) (X=hydridotris(pyrazolyl)borate (Tp) and cyclopentadiene (Cp); L=Cl and N3) are investigated by using density functional theory (DFT) with DZVP2/DZVP all-electron mixed basis sets and compared with available experimental values, and the calculated structures are in very good agreement with experimental data. neotetrazolium 80-82 protein phosphatase 4 catalytic subunit Homo sapiens 30-34 22029414-0 2011 Synthesis, structures, and reactivity of yttrium alkyl and alkynyl complexes with mixed Tp(Me2)/Cp ligands. neotetrazolium 88-90 malic enzyme 2 Homo sapiens 91-94 22029414-1 2011 The structurally characterized Tp(Me2)-supported rare earth metal monoalkyl complex (Tp(Me2))CpYCH(2)Ph(THF) (1) was synthesized via the salt-metathesis reaction of (Tp(Me2))CpYCl(THF) with KCH(2)Ph in THF at room temperature. neotetrazolium 31-33 malic enzyme 2 Homo sapiens 34-37 22029414-1 2011 The structurally characterized Tp(Me2)-supported rare earth metal monoalkyl complex (Tp(Me2))CpYCH(2)Ph(THF) (1) was synthesized via the salt-metathesis reaction of (Tp(Me2))CpYCl(THF) with KCH(2)Ph in THF at room temperature. neotetrazolium 31-33 malic enzyme 2 Homo sapiens 88-91 22029414-1 2011 The structurally characterized Tp(Me2)-supported rare earth metal monoalkyl complex (Tp(Me2))CpYCH(2)Ph(THF) (1) was synthesized via the salt-metathesis reaction of (Tp(Me2))CpYCl(THF) with KCH(2)Ph in THF at room temperature. neotetrazolium 31-33 malic enzyme 2 Homo sapiens 88-91 20668692-2 2010 Human cdc25C is phosphorylated on Proline-dependent SP and TP sites when it becomes active at mitosis and the prevalent model is that this phosphorylation/activation of cdc25C would be part of an amplification loop with cdk1/cyclin B1. neotetrazolium 59-61 cell division cycle 25C Homo sapiens 6-12 21336108-13 2011 The serum levels of both cystatin C and creatinine were significantly higher in the control group than in the TP group on postoperative day 2. neotetrazolium 110-112 cystatin C Homo sapiens 25-35 21894968-3 2011 The resulting complexes TEA[Tp*MoX(S(2)BMOQO)] [1, X = S; 3, X = O; TEA = tetraethylammonium; Tp* = hydrotris(3,5-dimethylpyrazolyl)borate] undergo a dehydration-driven intramolecular cyclization within quinoxalyldithiolene, forming Tp*MoX(pyrrolo-S(2)BMOQO) (2, X = S; 4, X = O). neotetrazolium 28-30 monooxygenase DBH like 1 Homo sapiens 31-34 21213358-8 2011 TP (5-100 nM) concentration-dependently inhibited the NFkappaB transcriptional activity induced by TNF-alpha, lipopolysaccharide and phorbol 12-myristate 13-acetate in HSC-T6 cells. neotetrazolium 0-2 tumor necrosis factor Rattus norvegicus 99-108 21282454-9 2011 d4T-TP levels were independently associated with the TS genotype (low versus high expression; odds ratio [OR] = 86.22; 95% confidence interval [CI] = 8.48 to nonestimable; P = 0.0023). neotetrazolium 4-6 thymidylate synthetase Homo sapiens 53-55 21282454-11 2011 Our preliminary data show that polymorphisms in the thymidylate synthase gene are strongly associated with d4T-TP intracellular levels and with development of HALS. neotetrazolium 111-113 thymidylate synthetase Homo sapiens 52-72 21251196-11 2011 Furthermore, thrombin-induced release of S1P was attenuated in platelets from TP-deficient mice. neotetrazolium 78-80 coagulation factor II Mus musculus 13-21 21251196-11 2011 Furthermore, thrombin-induced release of S1P was attenuated in platelets from TP-deficient mice. neotetrazolium 78-80 sphingosine-1-phosphate receptor 1 Mus musculus 41-44 21330834-11 2011 In the NACT + RS group, NACT with TP improves the long-term DFS and OS of patients compared with patients who had PVB chemotherapy regimen. neotetrazolium 34-36 solute carrier family 13 member 5 Homo sapiens 7-11 21330834-11 2011 In the NACT + RS group, NACT with TP improves the long-term DFS and OS of patients compared with patients who had PVB chemotherapy regimen. neotetrazolium 34-36 solute carrier family 13 member 5 Homo sapiens 24-28 20668692-2 2010 Human cdc25C is phosphorylated on Proline-dependent SP and TP sites when it becomes active at mitosis and the prevalent model is that this phosphorylation/activation of cdc25C would be part of an amplification loop with cdk1/cyclin B1. neotetrazolium 59-61 cell division cycle 25C Homo sapiens 169-175 19853959-5 2010 I-BOP, an agonist of TP, stimulated the expression of VEGF in this cell line as well as in another human lung cancer H157 cells in a time and dose dependent manner. neotetrazolium 21-23 vascular endothelial growth factor A Homo sapiens 54-58 20050605-2 2010 The bis(tetrahydrofuran) adduct, Tp*UI(2)(THF)(2) (1) (Tp* = hydrotris(3,5-dimethylpyrazolyl)borate), was synthesized by addition of sodium hydrotris(3,5-dimethylpyrazolyl)borate (NaTp*) to an equivalent of UI(3)(THF)(4). neotetrazolium 33-35 N-acetyltransferase pseudogene Homo sapiens 180-185 19488439-0 2009 Reactions of Tp(NH[double bond, length as m-dash]CPh(2))(PPh(3))Ru-Cl with HC[triple bond, length as m-dash]CPh in the presence of H(2)O: insertion/hydration products. neotetrazolium 13-15 caveolin 1 Homo sapiens 57-63 19801655-3 2009 Mass spectrometry analyses revealed that Rad53 is phosphorylated at multiple SQ/TQ and at SP/TP residues, which are typical consensus sites for phosphatidylinositol 3-kinase-related kinases and CDKs, respectively. neotetrazolium 93-95 serine/threonine/tyrosine protein kinase RAD53 Saccharomyces cerevisiae S288C 41-46 19801655-3 2009 Mass spectrometry analyses revealed that Rad53 is phosphorylated at multiple SQ/TQ and at SP/TP residues, which are typical consensus sites for phosphatidylinositol 3-kinase-related kinases and CDKs, respectively. neotetrazolium 93-95 cyclin-dependent serine/threonine-protein kinase CDC28 Saccharomyces cerevisiae S288C 194-198 19403525-4 2009 TP-induced suppression of both eNOS and Akt phosphorylation was accompanied by up-regulation of PTEN (phosphatase and tension homolog deleted on chromosome 10), Ser(380)/Thr(382/383) PTEN phosphorylation, and PTEN lipid phosphatase activity. neotetrazolium 0-2 nitric oxide synthase 3, endothelial cell Mus musculus 31-35 19403525-4 2009 TP-induced suppression of both eNOS and Akt phosphorylation was accompanied by up-regulation of PTEN (phosphatase and tension homolog deleted on chromosome 10), Ser(380)/Thr(382/383) PTEN phosphorylation, and PTEN lipid phosphatase activity. neotetrazolium 0-2 thymoma viral proto-oncogene 1 Mus musculus 40-43 19403525-4 2009 TP-induced suppression of both eNOS and Akt phosphorylation was accompanied by up-regulation of PTEN (phosphatase and tension homolog deleted on chromosome 10), Ser(380)/Thr(382/383) PTEN phosphorylation, and PTEN lipid phosphatase activity. neotetrazolium 0-2 phosphatase and tensin homolog Mus musculus 96-100 19403525-4 2009 TP-induced suppression of both eNOS and Akt phosphorylation was accompanied by up-regulation of PTEN (phosphatase and tension homolog deleted on chromosome 10), Ser(380)/Thr(382/383) PTEN phosphorylation, and PTEN lipid phosphatase activity. neotetrazolium 0-2 phosphatase and tensin homolog Mus musculus 183-187 19403525-4 2009 TP-induced suppression of both eNOS and Akt phosphorylation was accompanied by up-regulation of PTEN (phosphatase and tension homolog deleted on chromosome 10), Ser(380)/Thr(382/383) PTEN phosphorylation, and PTEN lipid phosphatase activity. neotetrazolium 0-2 phosphatase and tensin homolog Mus musculus 183-187 19464661-7 2009 Furthermore, TP-mediated phosphoinositide hydrolysis, phosphorylation of extracellular signal-regulated kinase (ERK) 1/2 and interleukin-6 production were reduced by the expression of KIAA1005/TPIP. neotetrazolium 13-15 mitogen-activated protein kinase 3 Homo sapiens 73-120 19464661-7 2009 Furthermore, TP-mediated phosphoinositide hydrolysis, phosphorylation of extracellular signal-regulated kinase (ERK) 1/2 and interleukin-6 production were reduced by the expression of KIAA1005/TPIP. neotetrazolium 13-15 interleukin 6 Homo sapiens 125-138 19464661-7 2009 Furthermore, TP-mediated phosphoinositide hydrolysis, phosphorylation of extracellular signal-regulated kinase (ERK) 1/2 and interleukin-6 production were reduced by the expression of KIAA1005/TPIP. neotetrazolium 13-15 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 Homo sapiens 193-197 19100618-4 2009 At very low concentration, TPS-LZM could significantly reverse the disease progression in renal ischemia-reperfusion (I/R) injury animal models, while the mixture of free TP and LZM was ineffective. neotetrazolium 27-29 lysozyme Homo sapiens 31-34 19619443-13 2009 In concurrent chemoradiotherapy, the application rate of granulocyte colony stimulating factor (G-CSF) was significantly higher in TP group than in DDP group (100% vs. 72.0%, p<0.05). neotetrazolium 131-133 colony stimulating factor 3 Homo sapiens 57-94 19619443-13 2009 In concurrent chemoradiotherapy, the application rate of granulocyte colony stimulating factor (G-CSF) was significantly higher in TP group than in DDP group (100% vs. 72.0%, p<0.05). neotetrazolium 131-133 colony stimulating factor 3 Homo sapiens 96-101 18702501-2 2008 We demonstrate that n-propanethiol successfully undergoes catalytic alkyne hydrothiolation with both aryl and aliphatic alkynes using Tp*Rh(PPh3)2 as the catalyst. neotetrazolium 134-137 caveolin 1 Homo sapiens 140-144 18358513-1 2008 The photocatalytic efficiency of two 2,4,6-triphenylpyrylium (TP(+)) based photocatalysts (supported on silica or incorporated inside zeolite Beta, 3wt%) for the degradation of 2,4-dichlorophenol (DCP) in aqueous media has been compared with TiO(2) (Degussa P-25). neotetrazolium 62-64 tubulin polymerization promoting protein Homo sapiens 258-262 18723487-11 2008 dFdU is taken up into cells with high affinity by hCNT1 and phosphorylated to its dFdU-TP metabolite. neotetrazolium 87-89 solute carrier family 28 member 1 Homo sapiens 50-55 18688399-4 2008 For [Rh(eta-cod){B(pz)4}], [Rh(eta-dmbd)Tp"] (dmbd = 2,3-dimethylbuta-1,3-diene) and [Rh(eta-cod)Tp(Ph)] {Tp(Ph) = hydrotris(3-phenylpyrazolyl)borate} the fluxional process is slowed at low temperatures so that inequivalent pyrazolyl rings are observed. neotetrazolium 40-42 endothelin receptor type A Homo sapiens 31-34 18688399-4 2008 For [Rh(eta-cod){B(pz)4}], [Rh(eta-dmbd)Tp"] (dmbd = 2,3-dimethylbuta-1,3-diene) and [Rh(eta-cod)Tp(Ph)] {Tp(Ph) = hydrotris(3-phenylpyrazolyl)borate} the fluxional process is slowed at low temperatures so that inequivalent pyrazolyl rings are observed. neotetrazolium 40-42 endothelin receptor type A Homo sapiens 31-34 18590695-7 2008 The distances between the protons of H11 and H18, H11 and H19, H15 and H18, and H15 and H19 in U46619 were shorter following their binding to the TP in solution, down to within 5A, which were different than that of the U46619 bound to PGIS and U44069 (another PGH(2) mimic) bound to TXAS. neotetrazolium 146-148 prostaglandin I2 synthase Homo sapiens 235-239 18590695-7 2008 The distances between the protons of H11 and H18, H11 and H19, H15 and H18, and H15 and H19 in U46619 were shorter following their binding to the TP in solution, down to within 5A, which were different than that of the U46619 bound to PGIS and U44069 (another PGH(2) mimic) bound to TXAS. neotetrazolium 146-148 thromboxane A synthase 1 Homo sapiens 283-287 18688399-9 2008 Of the complexes with the more sterically hindered Tp(Ph) ligand, only [Rh(eta-nbd)Tp(Ph)] shows any degree of reversible oxidation. neotetrazolium 82-85 endothelin receptor type A Homo sapiens 75-78 17765313-2 2007 The new models are distinctive for the inclusion of pterin-substituted dithiolene chelates and have the formulation Tp(*)MoX(pterin-R-dithiolene) (Tp(*)=tris(3,5,-dimethylpyrazolyl)borate), X=O, S, R=aryl. neotetrazolium 116-118 monooxygenase DBH like 1 Homo sapiens 121-124 18187198-1 2008 The oxygen atom transfer reactivity of Tp( *)MoO(2)(SPh) (1) (where Tp( *)=hydrotris-(3,5-dimethylpyrazol-1-yl)borate) with trimethyl phosphine (PMe(3)) has been investigated. neotetrazolium 39-41 surfactant associated 3 Homo sapiens 52-55 17765313-2 2007 The new models are distinctive for the inclusion of pterin-substituted dithiolene chelates and have the formulation Tp(*)MoX(pterin-R-dithiolene) (Tp(*)=tris(3,5,-dimethylpyrazolyl)borate), X=O, S, R=aryl. neotetrazolium 147-149 monooxygenase DBH like 1 Homo sapiens 121-124 17499743-6 2007 In addition, TP-mediated phosphoinositide hydrolysis was clearly observed in TP alpha-, but not TP beta-expressing cells. neotetrazolium 13-15 plasminogen activator, tissue type Homo sapiens 77-85 17632087-2 2007 I-BOP, a TP agonist, induced a time- and dose-dependent expression of COX-2 in A549-TPalpha cells. neotetrazolium 9-11 BOP Homo sapiens 2-5 17632087-2 2007 I-BOP, a TP agonist, induced a time- and dose-dependent expression of COX-2 in A549-TPalpha cells. neotetrazolium 9-11 prostaglandin-endoperoxide synthase 2 Homo sapiens 70-75 17632087-2 2007 I-BOP, a TP agonist, induced a time- and dose-dependent expression of COX-2 in A549-TPalpha cells. neotetrazolium 9-11 plasminogen activator, tissue type Homo sapiens 84-91 17160175-3 2007 The dependence of both oxidation potential and nu(CO) for [MX(CO)(eta-RC[triple bond, length as m-dash]CR)Tp"] shows an inverse halide order which is consistent with an ionic component to the M-X bond; the small size of fluorine and its closeness to the metal centre leads to the highest energy HOMO and the lowest oxidation potential. neotetrazolium 106-108 endothelin receptor type A Homo sapiens 66-69 17241518-9 2007 TP induced a robust activation of Akt and the inactivation of GSK3beta via PI3-K. neotetrazolium 0-2 AKT serine/threonine kinase 1 Rattus norvegicus 34-37 17241518-9 2007 TP induced a robust activation of Akt and the inactivation of GSK3beta via PI3-K. neotetrazolium 0-2 glycogen synthase kinase 3 beta Rattus norvegicus 62-70 16688324-1 2006 The synthesis and characterisation of the cyclobutyl complex Tp(Me2)NbCl(c-C4H7)(MeC[triple bond]CMe) completes the family of cycloalkyl complexes Tp(Me2)NbCl(c-C(n)H(2n-1)), n = 3-6. neotetrazolium 61-63 malic enzyme 2 Homo sapiens 64-67 16782917-7 2006 Improved clinical outcomes with TPC were most evident in HER-2 3+ patients, with an ORR of 57% (95% CI, 45% to 70%) v 36% (95% CI, 25% to 48%; P = .03) and median PFS of 13.8 v 7.6 months (P = .005) for TPC and TP, respectively (HR, 0.55; 95% CI, 0.46 to 0.64). neotetrazolium 32-34 erb-b2 receptor tyrosine kinase 2 Homo sapiens 57-62 16688324-1 2006 The synthesis and characterisation of the cyclobutyl complex Tp(Me2)NbCl(c-C4H7)(MeC[triple bond]CMe) completes the family of cycloalkyl complexes Tp(Me2)NbCl(c-C(n)H(2n-1)), n = 3-6. neotetrazolium 61-63 C-C motif chemokine ligand 28 Homo sapiens 81-84 16688324-1 2006 The synthesis and characterisation of the cyclobutyl complex Tp(Me2)NbCl(c-C4H7)(MeC[triple bond]CMe) completes the family of cycloalkyl complexes Tp(Me2)NbCl(c-C(n)H(2n-1)), n = 3-6. neotetrazolium 61-63 malic enzyme 2 Homo sapiens 150-153 16351085-3 2005 We report herein that Tp*Rh(PPh3)2 (Tp* = hydrotris(3,5-dimethylpyrazolyl)borate) is a highly active catalyst for alkyne hydrothiolation with alkyl and aryl thiols. neotetrazolium 22-24 caveolin 1 Homo sapiens 28-32 16567086-7 2006 Our findings revealed a decrease in prostate growth in the NMU/TP/GLA-fed group as determined by weight, tissue size, DNA content and prostate-specific antigen (tumor marker of prostate cancer). neotetrazolium 63-65 neuromedin U Homo sapiens 59-62 16567086-7 2006 Our findings revealed a decrease in prostate growth in the NMU/TP/GLA-fed group as determined by weight, tissue size, DNA content and prostate-specific antigen (tumor marker of prostate cancer). neotetrazolium 63-65 kallikrein related peptidase 3 Homo sapiens 134-192 16567086-8 2006 Comparison between the two groups showed a significant increase in 5S-hydroxyeicosatetraenoic acid and prostaglandin E(2) in the NMU/TP group. neotetrazolium 133-135 neuromedin U Homo sapiens 129-132 16441102-1 2006 X-ray crystallography and resonance Raman (rR) spectroscopy have been used to further characterize (Tp*)MoO(qdt) (Tp* is hydrotris(3,5-dimethyl-1-pyrazolyl)borate and qdt is 2,3-quinoxalinedithiolene), which represents an important benchmark oxomolybdenum mono-dithiolene model system relevant to various pyranopterin Mo enzyme active sites, including sulfite oxidase. neotetrazolium 100-102 sulfite oxidase Homo sapiens 352-367 16351085-3 2005 We report herein that Tp*Rh(PPh3)2 (Tp* = hydrotris(3,5-dimethylpyrazolyl)borate) is a highly active catalyst for alkyne hydrothiolation with alkyl and aryl thiols. neotetrazolium 36-38 caveolin 1 Homo sapiens 28-32 16234937-2 2005 As well, a novel "organoscorpionate" complex, [W{S2C2(CO2Me)2}{SC2(CO2Me)2-Tp*}], has been isolated from the reactions of NEt4[Tp*WS3] with excess DMAC. neotetrazolium 75-77 tetraspanin 5 Homo sapiens 122-126 16322691-7 2005 However, TP-DC vaccination in vivo increased the IFN-gamma production from splenocytes higher than that of UP-DC (TP- vs. UP-DC; 41029+/-1523 vs. 4752+/-590 pg/ml, respectively). neotetrazolium 9-11 interferon gamma Mus musculus 49-58 15759894-1 2004 Under the condition of keeping the influent COD: TN: TP = 100:5:1, submerged MBR has an excellent treatment performance for COD and NH4+ -N, and the removals for COD and NH4+ -N are both beyond 90% under steady state, in addition, MBR has a strong adaptation ability for shock organics loading rate. neotetrazolium 53-55 translocator protein Homo sapiens 77-80 15884057-3 2005 One G protein receptor that can couple to Galpha(12/13) subunits is the receptor for thromboxane A(2 )(TXA(2)), thromboxane-prostanoid (called TP), which is highly expressed in immature thymocytes. neotetrazolium 143-145 thromboxane A2 receptor Mus musculus 112-134 15786505-1 2005 Intermediates in the oxygen atom transfer from Mo(VI) to P(III), [Tp(iPr)MoOX(OPR3)] (Tp(iPr) = hydrotris(3-isopropylpyrazol-1-yl)borate; X = Cl-, phenolates, thiolates), have been isolated from the reactions of [Tp(iPr)MoO2X] with phosphines (PEt3, PMePh2, PPh3). neotetrazolium 66-68 protein phosphatase 4 catalytic subunit Homo sapiens 258-262 15786505-1 2005 Intermediates in the oxygen atom transfer from Mo(VI) to P(III), [Tp(iPr)MoOX(OPR3)] (Tp(iPr) = hydrotris(3-isopropylpyrazol-1-yl)borate; X = Cl-, phenolates, thiolates), have been isolated from the reactions of [Tp(iPr)MoO2X] with phosphines (PEt3, PMePh2, PPh3). neotetrazolium 86-88 protein phosphatase 4 catalytic subunit Homo sapiens 258-262 15759894-1 2004 Under the condition of keeping the influent COD: TN: TP = 100:5:1, submerged MBR has an excellent treatment performance for COD and NH4+ -N, and the removals for COD and NH4+ -N are both beyond 90% under steady state, in addition, MBR has a strong adaptation ability for shock organics loading rate. neotetrazolium 53-55 translocator protein Homo sapiens 231-234 12844309-1 2003 The electronic and magnetic properties of a series of mixed-sandwich complexes MCp(R)Tp (Cp(R) = Cp or Cp; Tp = hydrotris(pyrazolyl)borate; M = V, Cr, Fe, Co or Ni) have been studied and compared to their homoleptic analogues, MCp(R)(2) and MTp(2). neotetrazolium 85-87 CD46 molecule Homo sapiens 79-82 15493934-1 2004 The arene ligand in the complex TpRe(CO)(MeIm)(eta2-benzene) (Tp = hydridotris(pyrazolyl)borate; MeIm = N-methylimidazole) undergoes tandem electrophile/nucleophile 1,4-addition reactions. neotetrazolium 32-34 DNA polymerase iota Homo sapiens 47-51 15500686-12 2004 Stromal immunostaining for COX-1 as well as COX-2 was increased in the TP and PP groups as compared to the NP, and GE displayed an intensely increased COX-2 immunostaining at term and postpartum. neotetrazolium 71-73 mitochondrially encoded cytochrome c oxidase I Homo sapiens 27-32 15500686-12 2004 Stromal immunostaining for COX-1 as well as COX-2 was increased in the TP and PP groups as compared to the NP, and GE displayed an intensely increased COX-2 immunostaining at term and postpartum. neotetrazolium 71-73 mitochondrially encoded cytochrome c oxidase II Homo sapiens 44-49 14557367-6 2003 Furthermore, in indomethacin-treated wild-type VSMCs, U-46619, a TP agonist, inhibited cytokine-induced iNOS expression and NO production in a concentration-dependent manner, effects absent from TP-/- VSMCs. neotetrazolium 65-67 nitric oxide synthase 2, inducible Mus musculus 104-108 12586835-4 2003 In mitotic HeLa cells, when the activity of Cdc2 is high, S6K1 is phosphorylated at multiple Ser/Thr, Pro (S/TP) sites, including Ser(371), Ser(411), Thr(421), and Ser(424). neotetrazolium 109-111 cyclin dependent kinase 1 Homo sapiens 44-48 12586835-4 2003 In mitotic HeLa cells, when the activity of Cdc2 is high, S6K1 is phosphorylated at multiple Ser/Thr, Pro (S/TP) sites, including Ser(371), Ser(411), Thr(421), and Ser(424). neotetrazolium 109-111 ribosomal protein S6 kinase B1 Homo sapiens 58-62 12639658-6 2003 The mean total dose and duration of morphine administration were higher in the TP-LRP group, but the difference was not statistically significant (6.0 mg versus 12.8 mg and 0.5 day versus 0.9 day, respectively). neotetrazolium 79-81 LDL receptor related protein 1 Homo sapiens 82-85 11710394-11 2001 On the contrary, myocardial NO generation and iNOS expression were significantly reduced after repeated inhalation of hypobaric oxygen at 5500 m. NO metabolism regained to normal after repeated administration of TP. neotetrazolium 212-214 nitric oxide synthase 2, inducible Mus musculus 46-50 12487134-1 2002 The (alpha =3, beta =2) member of the (A3ABO6) (A3B3O9) homologous series has been stabilised in the Sr-Rh-O system for a [Sr10(Sr0.5Rh1.5)TP(Rh6)Oh]O24 composition. neotetrazolium 139-141 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 5-22 12093179-5 2002 Immunoprecipitation of each deletion mutant protein by M2 beads showed that binding of Hsp60 to human HBV Pol requires two minimal sites on human HBV Pol: amino acids 1 to 199 (TP) and amino acids 680 to 842 (RH). neotetrazolium 177-179 heat shock protein family D (Hsp60) member 1 Homo sapiens 87-92 12565868-6 2003 TP inhibited a number of steps in the cisplatin-induced apoptotic pathway, activation of caspases 3 and 9 and mitochondrial cytochrome c release. neotetrazolium 0-2 caspase 3 Homo sapiens 89-105 12565868-6 2003 TP inhibited a number of steps in the cisplatin-induced apoptotic pathway, activation of caspases 3 and 9 and mitochondrial cytochrome c release. neotetrazolium 0-2 cytochrome c, somatic Homo sapiens 124-136 12120080-0 2002 Synthesis of the RuIV amido complex [TpRu(CO)(PPh3)(NHPh)][OTf]2 (Tp = hydridotris(pyrazolyl)borate; OTf = trifluoromethanesulfonate) and deprotonation to form an octahedral and d4 imido complex: computational study of RuIV-imido bonding. neotetrazolium 37-39 caveolin 1 Homo sapiens 46-50 10887296-1 2000 Covalently bound conjugates of alpha-fetoprotein (AFP) and epidermal growth factor (EGF) with photoheme (PH), 3-desvinyl-3-formylchlorine p6 (Chl p6), chlorine e6 (Chl e6), aluminum disulfochloride phthalocyanine (PC(Al)), and cobalt octa-4,5-carboxyphthalocyanine (teraphthal, TP(Co)) were synthesized. neotetrazolium 278-280 alpha fetoprotein Homo sapiens 31-48 10887296-1 2000 Covalently bound conjugates of alpha-fetoprotein (AFP) and epidermal growth factor (EGF) with photoheme (PH), 3-desvinyl-3-formylchlorine p6 (Chl p6), chlorine e6 (Chl e6), aluminum disulfochloride phthalocyanine (PC(Al)), and cobalt octa-4,5-carboxyphthalocyanine (teraphthal, TP(Co)) were synthesized. neotetrazolium 278-280 alpha fetoprotein Homo sapiens 50-53 10887296-1 2000 Covalently bound conjugates of alpha-fetoprotein (AFP) and epidermal growth factor (EGF) with photoheme (PH), 3-desvinyl-3-formylchlorine p6 (Chl p6), chlorine e6 (Chl e6), aluminum disulfochloride phthalocyanine (PC(Al)), and cobalt octa-4,5-carboxyphthalocyanine (teraphthal, TP(Co)) were synthesized. neotetrazolium 278-280 epidermal growth factor Homo sapiens 59-82 10887296-1 2000 Covalently bound conjugates of alpha-fetoprotein (AFP) and epidermal growth factor (EGF) with photoheme (PH), 3-desvinyl-3-formylchlorine p6 (Chl p6), chlorine e6 (Chl e6), aluminum disulfochloride phthalocyanine (PC(Al)), and cobalt octa-4,5-carboxyphthalocyanine (teraphthal, TP(Co)) were synthesized. neotetrazolium 278-280 epidermal growth factor Homo sapiens 84-87 10455234-6 1999 SAC1 encodes a protein which has been previously implicated in the correct function of the actin cytoskeleton, in inositol metabolism, in ATP transport in the endoplasmic reticulum and in Sec14p (PI-TP) function. neotetrazolium 139-141 phosphatidylinositol-3-phosphatase SAC1 Saccharomyces cerevisiae S288C 0-4 11272552-0 2000 Comparing the isoelectronic complexes [RuTp(CH3CN)3]PF6 (Tp = hydridotris(pyrazolyl)borate) and. neotetrazolium 41-43 sperm associated antigen 17 Homo sapiens 52-55 10582692-2 1999 Previous studies have shown that the oxygen insensitivity of the histochemical reaction to detect glucose-6-phosphate dehydrogenase activity based on neotetrazolium reduction can be used for discriminating malignant cells from nonmalignant cells. neotetrazolium 150-164 glucose-6-phosphate dehydrogenase Homo sapiens 98-131 9313928-5 1997 The DP, IP and TP receptors showed high ligand binding specificity and only bound their own putative ligands with high affinity such as PGD2, BW245C and BW868C for DP, cicaprost, iloprost and isocabacyclin for IP, and S-145, I-BOP and GR 32191 for TP. neotetrazolium 15-17 prostaglandin D2 synthase (brain) Mus musculus 136-140 9799628-7 1998 TP and EB, but not DHTP, masculinized CA1 pyramidal cell field volume and neuronal soma size; CA3 was masculinized in both TP- and DHTP-treated females, while EB was ineffective. neotetrazolium 0-2 carbonic anhydrase 1 Rattus norvegicus 38-41 9359428-4 1997 Both full activation by Ca2+ ions and stimulation in the presence of PI-TP require an intact PH domain involved in the membrane attachment of PLCdelta1. neotetrazolium 72-74 phospholipase C delta 1 Homo sapiens 142-151 9485026-7 1998 Inhibitory effects of TP-69 or TP-72 on iNOS formation were not blocked by the glucocorticoid receptor antagonist RU-486, indicating that these triterpenoids do not act through the glucocorticoid receptor, nor does TP-72 act as an iNOS or COX-2 enzyme inhibitor when added to RAW cells in which synthesis of these two enzymes in response to LPS has already been induced. neotetrazolium 22-24 nitric oxide synthase 2, inducible Mus musculus 40-44 9485026-7 1998 Inhibitory effects of TP-69 or TP-72 on iNOS formation were not blocked by the glucocorticoid receptor antagonist RU-486, indicating that these triterpenoids do not act through the glucocorticoid receptor, nor does TP-72 act as an iNOS or COX-2 enzyme inhibitor when added to RAW cells in which synthesis of these two enzymes in response to LPS has already been induced. neotetrazolium 31-33 nitric oxide synthase 2, inducible Mus musculus 40-44 7583124-2 1995 Here, we test the hypothesis that the principal role of PI-TP is to couple sites of lipid hydrolysis to sites of synthesis, and so to replenish depleted substrate for PLC-beta. neotetrazolium 59-61 heparan sulfate proteoglycan 2 Homo sapiens 167-170 9306960-1 1997 The effects of oxygen on the quantitative histochemical assay to detect glucose-6-phosphate dehydrogenase (G6PDH) activity based on neotetrazolium reduction were studied in the different stages of carcinogenesis in the colon. neotetrazolium 132-146 glucose-6-phosphate dehydrogenase Homo sapiens 72-105 9306960-1 1997 The effects of oxygen on the quantitative histochemical assay to detect glucose-6-phosphate dehydrogenase (G6PDH) activity based on neotetrazolium reduction were studied in the different stages of carcinogenesis in the colon. neotetrazolium 132-146 glucose-6-phosphate dehydrogenase Homo sapiens 107-112 7583124-10 1995 CONCLUSIONS: The predicted function of PI-TP in inositol lipid signalling is the provision of substrate for PLC-beta from intracellular sites where PI is synthesized. neotetrazolium 42-44 heparan sulfate proteoglycan 2 Homo sapiens 108-111 1934006-1 1991 Immunohistochemically detectable erythropoietin-like substance(Epo) in granular convoluted tubule(GCT) cells of submandibular glands (SMG"s) was examined in mice in which hemolytic anemia had been induced by phenylhydrazine (ph), and in mice subjected to hypoxia, nephrectomy, or testosterone (TP) injections. neotetrazolium 294-296 erythropoietin Mus musculus 63-66 2379174-1 1990 It was found to be possible to distinguish malignant cells from normal cells by using an oxygen-sensitive tetrazolium salt (neotetrazolium) for the histochemical demonstration of glucose-6-phosphate dehydrogenase activity in cryostat sections of human colon. neotetrazolium 124-138 glucose-6-phosphate dehydrogenase Homo sapiens 179-212 17944460-10 2007 X-ray diffraction studies of K[Tp"(CO)(Me3CNC)Mo(eta2-C2S2)] (K-3c), 4b, 6a, 6b, and 7 are included. neotetrazolium 31-34 DNA polymerase iota Homo sapiens 49-53 7930518-1 1994 We used the oxygen sensitivity of the histochemical reaction to detect glucose-6-phosphate dehydrogenase (G6PDH) activity based on neotetrazolium (NT) reduction to discriminate cancer cells from normal cells. neotetrazolium 131-145 glucose-6-phosphate dehydrogenase Rattus norvegicus 71-104 7930518-1 1994 We used the oxygen sensitivity of the histochemical reaction to detect glucose-6-phosphate dehydrogenase (G6PDH) activity based on neotetrazolium (NT) reduction to discriminate cancer cells from normal cells. neotetrazolium 131-145 glucose-6-phosphate dehydrogenase Rattus norvegicus 106-111 7930518-1 1994 We used the oxygen sensitivity of the histochemical reaction to detect glucose-6-phosphate dehydrogenase (G6PDH) activity based on neotetrazolium (NT) reduction to discriminate cancer cells from normal cells. neotetrazolium 147-149 glucose-6-phosphate dehydrogenase Rattus norvegicus 71-104 7930518-1 1994 We used the oxygen sensitivity of the histochemical reaction to detect glucose-6-phosphate dehydrogenase (G6PDH) activity based on neotetrazolium (NT) reduction to discriminate cancer cells from normal cells. neotetrazolium 147-149 glucose-6-phosphate dehydrogenase Rattus norvegicus 106-111 7930518-10 1994 These experiments clearly indicate that the oxygen sensitivity phenomenon is not solely an effect of competition for reducing equivalents between NT and oxygen via SOD, because NADPH generated by G6PDH and NADH generated by LDH have a similar redox potential. neotetrazolium 146-148 glucose-6-phosphate dehydrogenase Rattus norvegicus 196-201 8223486-5 1993 These collective data demonstrate that while the in vitro PI-TP activity of SEC14p clearly reflects some functional in vivo property of SEC14p, the PI-TP activity is not the sole essential activity of SEC14p. neotetrazolium 61-63 phosphatidylinositol/phosphatidylcholine transfer protein SEC14 Saccharomyces cerevisiae S288C 76-82