PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
17892941-0	2007	Syntheses of immunomodulating androstanes and stigmastanes: comparison of their TNF-alpha inhibitory activity.	Androstanes	30-41	tumor necrosis factor	Homo sapiens	80-89
21215765-0	2011	Synthesis of some novel androstanes as potential aromatase inhibitors.	Androstanes	24-35	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	49-58
11405283-4	2001	The luciferase expression in CAR-producing cells could be suppressed by androstanes and reactivated by structurally unrelated drugs chlorpromazine, metyrapone, phenobarbital, and clotrimazole.	Androstanes	72-83	nuclear receptor subfamily 1 group I member 3	Homo sapiens	29-32
12904068-4	2003	Thus, oxidation of C-6 and introduction in the C-3 position of the potent pharmacophoric group recently introduced by us, in the 17 position of the digitalis skeleton, namely, O-(omega-aminoalkyl)oxime, led to a series of substituted androstanes able to inhibit the Na(+),K(+)-ATPase, most of them with an IC(50) in the low micromolar level, and to induce a positive inotropic effect in guinea pig.	Androstanes	234-245	complement C3	Cavia porcellus	47-50
10757780-3	2000	CAR has previously been shown to be an apparently constitutive transactivator, and this constitutive activity is inhibited by androstanes acting as inverse agonists.	Androstanes	126-137	CXADR pseudogene 1	Homo sapiens	0-3
33157220-0	2021	Modified bile acids and androstanes - novel promising inhibitors of human cytochrome P450 17A1.	Androstanes	24-35	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	74-94