PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21083240-2	2010	In addition, a number of other enzymes or enzyme families contribute to the metabolism of xenobiotica, including alcohol dehydrogenase, aldehyde dehydrogenase, ester and amide hydrolases, epoxide hydrolase and flavine monooxygenases, as well as sulfotransferases, catechol-O-methyltransferase and N-acetyltransferase.	xenobiotica	90-101	aldo-keto reductase family 1 member A1	Homo sapiens	113-134
116125-0	1979	Xenobiotica-metabolizing enzymes in Drosophila melanogaster: activities of epoxide hydratase and glutathione S-transferase compared with similar activities in rat liver.	xenobiotica	0-11	epoxide hydrolase 2	Rattus norvegicus	75-92
116125-0	1979	Xenobiotica-metabolizing enzymes in Drosophila melanogaster: activities of epoxide hydratase and glutathione S-transferase compared with similar activities in rat liver.	xenobiotica	0-11	Glutathione S transferase D4	Drosophila melanogaster	97-122
29916051-4	2018	This review collects available information of which-taken with great caution because of the still very limited data-the most salient points are: in the skin of all animal species and skin-derived in vitro systems considered in this review cytochrome P450 (CYP)-dependent monooxygenase activities (largely responsible for initiating xenobiotica metabolism in the organ which provides most of the xenobiotica metabolism of the mammalian organism, the liver) are very low to undetectable.	xenobiotica	332-343	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	239-254
29916051-4	2018	This review collects available information of which-taken with great caution because of the still very limited data-the most salient points are: in the skin of all animal species and skin-derived in vitro systems considered in this review cytochrome P450 (CYP)-dependent monooxygenase activities (largely responsible for initiating xenobiotica metabolism in the organ which provides most of the xenobiotica metabolism of the mammalian organism, the liver) are very low to undetectable.	xenobiotica	332-343	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	256-259
21083240-2	2010	In addition, a number of other enzymes or enzyme families contribute to the metabolism of xenobiotica, including alcohol dehydrogenase, aldehyde dehydrogenase, ester and amide hydrolases, epoxide hydrolase and flavine monooxygenases, as well as sulfotransferases, catechol-O-methyltransferase and N-acetyltransferase.	xenobiotica	90-101	catechol-O-methyltransferase	Homo sapiens	264-292
18072750-4	2008	The AhR is activated by xenobiotica such as dioxins.	xenobiotica	24-35	aryl hydrocarbon receptor	Homo sapiens	4-7