PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
34721047-10	2021	Ticagrelor-O-glucuronide also exhibited limited inhibitory effects toward CYP2C8, CYP2D6 and CYP3A4.	ticagrelor-o-glucuronide	0-24	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	74-80
34721047-10	2021	Ticagrelor-O-glucuronide also exhibited limited inhibitory effects toward CYP2C8, CYP2D6 and CYP3A4.	ticagrelor-o-glucuronide	0-24	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	82-88
34721047-10	2021	Ticagrelor-O-glucuronide also exhibited limited inhibitory effects toward CYP2C8, CYP2D6 and CYP3A4.	ticagrelor-o-glucuronide	0-24	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	93-99
34721047-11	2021	In contrast, ticagrelor-O-glucuronide weakly inhibited CYP2B6, CYP2C9 and CYP2C19 activity with apparent IC50 values of 45.0, 20.0 and 18.8 muM, respectively.	ticagrelor-o-glucuronide	13-37	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	55-61
34721047-11	2021	In contrast, ticagrelor-O-glucuronide weakly inhibited CYP2B6, CYP2C9 and CYP2C19 activity with apparent IC50 values of 45.0, 20.0 and 18.8 muM, respectively.	ticagrelor-o-glucuronide	13-37	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	63-69
34721047-11	2021	In contrast, ticagrelor-O-glucuronide weakly inhibited CYP2B6, CYP2C9 and CYP2C19 activity with apparent IC50 values of 45.0, 20.0 and 18.8 muM, respectively.	ticagrelor-o-glucuronide	13-37	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	74-81
34721047-7	2021	Study with recombinant human UGTs suggested that multiple UGT isoforms including UGT1A9, UGT1A7, UGT1A3, UGT1A4, UGT1A1, UGT2B7 and UGT1A8 are involved in the conversion of ticagrelor to ticagrelor-O-glucuronide with UGT1A9 showing highest catalytic activity.	ticagrelor-o-glucuronide	187-211	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	58-61
34721047-7	2021	Study with recombinant human UGTs suggested that multiple UGT isoforms including UGT1A9, UGT1A7, UGT1A3, UGT1A4, UGT1A1, UGT2B7 and UGT1A8 are involved in the conversion of ticagrelor to ticagrelor-O-glucuronide with UGT1A9 showing highest catalytic activity.	ticagrelor-o-glucuronide	187-211	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	81-87
34721047-7	2021	Study with recombinant human UGTs suggested that multiple UGT isoforms including UGT1A9, UGT1A7, UGT1A3, UGT1A4, UGT1A1, UGT2B7 and UGT1A8 are involved in the conversion of ticagrelor to ticagrelor-O-glucuronide with UGT1A9 showing highest catalytic activity.	ticagrelor-o-glucuronide	187-211	UDP glucuronosyltransferase family 1 member A7	Homo sapiens	89-95
34721047-7	2021	Study with recombinant human UGTs suggested that multiple UGT isoforms including UGT1A9, UGT1A7, UGT1A3, UGT1A4, UGT1A1, UGT2B7 and UGT1A8 are involved in the conversion of ticagrelor to ticagrelor-O-glucuronide with UGT1A9 showing highest catalytic activity.	ticagrelor-o-glucuronide	187-211	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	97-103
34721047-7	2021	Study with recombinant human UGTs suggested that multiple UGT isoforms including UGT1A9, UGT1A7, UGT1A3, UGT1A4, UGT1A1, UGT2B7 and UGT1A8 are involved in the conversion of ticagrelor to ticagrelor-O-glucuronide with UGT1A9 showing highest catalytic activity.	ticagrelor-o-glucuronide	187-211	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	105-111
34721047-7	2021	Study with recombinant human UGTs suggested that multiple UGT isoforms including UGT1A9, UGT1A7, UGT1A3, UGT1A4, UGT1A1, UGT2B7 and UGT1A8 are involved in the conversion of ticagrelor to ticagrelor-O-glucuronide with UGT1A9 showing highest catalytic activity.	ticagrelor-o-glucuronide	187-211	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	113-119
34721047-7	2021	Study with recombinant human UGTs suggested that multiple UGT isoforms including UGT1A9, UGT1A7, UGT1A3, UGT1A4, UGT1A1, UGT2B7 and UGT1A8 are involved in the conversion of ticagrelor to ticagrelor-O-glucuronide with UGT1A9 showing highest catalytic activity.	ticagrelor-o-glucuronide	187-211	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	121-127
34721047-7	2021	Study with recombinant human UGTs suggested that multiple UGT isoforms including UGT1A9, UGT1A7, UGT1A3, UGT1A4, UGT1A1, UGT2B7 and UGT1A8 are involved in the conversion of ticagrelor to ticagrelor-O-glucuronide with UGT1A9 showing highest catalytic activity.	ticagrelor-o-glucuronide	187-211	UDP glucuronosyltransferase family 1 member A8	Homo sapiens	132-138
34721047-7	2021	Study with recombinant human UGTs suggested that multiple UGT isoforms including UGT1A9, UGT1A7, UGT1A3, UGT1A4, UGT1A1, UGT2B7 and UGT1A8 are involved in the conversion of ticagrelor to ticagrelor-O-glucuronide with UGT1A9 showing highest catalytic activity.	ticagrelor-o-glucuronide	187-211	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	217-223