PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 34352329-10 2021 RESULTS: QHZG pretreatment significantly abolished the increased secretion of cytokines such as interleukin-2 (IL-2), IL-1beta, IFN-gamma, and tumor necrosis factor-alpha (TNF-alpha), which were attributable to LPS treatment. qhzg 9-13 interleukin 2 Mus musculus 96-109 34352329-10 2021 RESULTS: QHZG pretreatment significantly abolished the increased secretion of cytokines such as interleukin-2 (IL-2), IL-1beta, IFN-gamma, and tumor necrosis factor-alpha (TNF-alpha), which were attributable to LPS treatment. qhzg 9-13 interleukin 2 Mus musculus 111-115 34352329-10 2021 RESULTS: QHZG pretreatment significantly abolished the increased secretion of cytokines such as interleukin-2 (IL-2), IL-1beta, IFN-gamma, and tumor necrosis factor-alpha (TNF-alpha), which were attributable to LPS treatment. qhzg 9-13 interleukin 1 alpha Mus musculus 118-126 34352329-10 2021 RESULTS: QHZG pretreatment significantly abolished the increased secretion of cytokines such as interleukin-2 (IL-2), IL-1beta, IFN-gamma, and tumor necrosis factor-alpha (TNF-alpha), which were attributable to LPS treatment. qhzg 9-13 interferon gamma Mus musculus 128-137 34352329-10 2021 RESULTS: QHZG pretreatment significantly abolished the increased secretion of cytokines such as interleukin-2 (IL-2), IL-1beta, IFN-gamma, and tumor necrosis factor-alpha (TNF-alpha), which were attributable to LPS treatment. qhzg 9-13 tumor necrosis factor Mus musculus 143-170 34352329-10 2021 RESULTS: QHZG pretreatment significantly abolished the increased secretion of cytokines such as interleukin-2 (IL-2), IL-1beta, IFN-gamma, and tumor necrosis factor-alpha (TNF-alpha), which were attributable to LPS treatment. qhzg 9-13 tumor necrosis factor Mus musculus 172-181 34352329-12 2021 Further study indicated that pretreatment with QHZG significantly inhibited LPS-induced phosphorylation of Src. qhzg 47-51 Rous sarcoma oncogene Mus musculus 107-110 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 142-146 Rous sarcoma oncogene Mus musculus 46-49 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 142-146 mitogen-activated protein kinase 8 Mus musculus 73-76 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 142-146 mitogen-activated protein kinase 1 Mus musculus 78-81 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 142-146 mitogen-activated protein kinase 14 Mus musculus 83-86 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 142-146 signal transducer and activator of transcription 3 Mus musculus 91-96 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 142-146 Rous sarcoma oncogene Mus musculus 178-181 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 142-146 signal transducer and activator of transcription 3 Mus musculus 187-192 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 230-234 Rous sarcoma oncogene Mus musculus 46-49 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 230-234 mitogen-activated protein kinase 8 Mus musculus 73-76 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 230-234 mitogen-activated protein kinase 1 Mus musculus 78-81 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 230-234 mitogen-activated protein kinase 14 Mus musculus 83-86 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 230-234 signal transducer and activator of transcription 3 Mus musculus 91-96 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 230-234 Rous sarcoma oncogene Mus musculus 178-181 34352329-13 2021 Accordingly, the increased phosphorylation of Src downstream components (JNK, ERK, P38 and STAT3) induced by LPS was remarkably diminished by QHZG, suggesting the involvement of Src/MAPK/STAT3 pathway in the inhibitory effects of QHZG on spleen injury in mice. qhzg 230-234 signal transducer and activator of transcription 3 Mus musculus 187-192 34352329-14 2021 CONCLUSION: Our study demonstrated that QHZG protected mice from LPS-induced acute spleen injury via inhibition of Src/MAPK/Stat3 signal pathway. qhzg 40-44 Rous sarcoma oncogene Mus musculus 115-118 34352329-14 2021 CONCLUSION: Our study demonstrated that QHZG protected mice from LPS-induced acute spleen injury via inhibition of Src/MAPK/Stat3 signal pathway. qhzg 40-44 signal transducer and activator of transcription 3 Mus musculus 124-129