PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 11020490-4 2000 The contractile effect of urotensin II was significantly inhibited by the phospholipase C inhibitor, 2-nitro-4-carboxyphenyl-N,N,-diphenylcarbamate (NCDC), but not by the cyclooxygenase inhibitor, indomethacin. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 101-147 urotensin 2 Homo sapiens 26-38 15760947-3 2005 Interference with D-myo-inositol 1,4,5-trisphosphate (IP3) induced Ca2+ release using 100 microm 2-aminoethoxydiphenyl borate, and the phospholipase C (PLC) inhibitors 2-nitro-4-carboxyphenyl N,N-diphenylcarbamate and U73122 decreased the amplitude of spontaneous oscillations but did not abolish them. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 168-213 LOC100009319 Oryctolagus cuniculus 152-155 12420796-4 2002 In the thoracic aorta both the phospholipase C inhibitor NCDC (10(-4) M) and the cyclooxygenase inhibitor indomethacin (10(-5) M) almost completely blocked the contractile effect of oestrogen. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 57-61 LOC100009319 Oryctolagus cuniculus 31-46 3129371-5 1988 Inhibition of atrial phospholipase C activity by nitrocarboxyphenyl N,N-diphenylcarbamate (NCDC, 5 X 10(-6)M) prevented the development of the inotropic positive effect of IL-2 in the presence of either AA or A 23187. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 91-95 interleukin 2 Homo sapiens 172-176 12784084-8 2003 The contractile response to 10 nmol/l ET-1 was inhibited by 10 micromol/l NCDC (to 80 +/- 6%) and 30 micromol/l H-7 (to 76.6 +/- 6.5%). 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 74-78 endothelin 1 Rattus norvegicus 38-42 12784084-11 2003 Additive inhibition of ET-1-induced contraction was not observed in the presence of both nifedipine and NCDC. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 104-108 endothelin 1 Rattus norvegicus 23-27 11020490-4 2000 The contractile effect of urotensin II was significantly inhibited by the phospholipase C inhibitor, 2-nitro-4-carboxyphenyl-N,N,-diphenylcarbamate (NCDC), but not by the cyclooxygenase inhibitor, indomethacin. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 149-153 urotensin 2 Homo sapiens 26-38 10395082-7 1999 AVP evoked an increase in [Ca2+]i levels (162 +/- 12 nmol/L from a basal value of 77 +/- 6 nmol/L) which was completely abolished by pretreatment with either NCDC or cyclopiazonic acid (sarcoplasmic reticulum (SR) Ca2+ pump inhibitor) but unaffected by ryanodine (ryanodine sensitive SR Ca2+ store depletor). 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 158-162 arginine vasopressin Rattus norvegicus 0-3 10511129-6 1999 The phospholipase C inhibitors, D-609, NCDC, or U73122, and the IP3 receptor blocker, heparin, abolished the [Ca2+]i response to AVP. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 39-43 arginine vasopressin Rattus norvegicus 129-132 9249599-4 1997 Inhibition of phospholipase C by treatment with 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC), inhibition of protein kinase C (PKC) by staurosporine, or long-term (24 h) treatment with phorbol 12-myristate 13-acetate (PMA) to downregulate PKC abolished most of the osmo-induced, dihydropyridine-sensitive calcium influx signal. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 48-93 LOC100009319 Oryctolagus cuniculus 14-29 10395082-4 1999 The stimulating action of AVP on [3H] phenylalanine incorporation was abolished by pretreatment with 2-nitro-4carboxyphenyl-N, N-diphenylcarbamate (NCDC), a phospholipase C (PLC) inhibitor. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 101-146 arginine vasopressin Rattus norvegicus 26-29 10395082-4 1999 The stimulating action of AVP on [3H] phenylalanine incorporation was abolished by pretreatment with 2-nitro-4carboxyphenyl-N, N-diphenylcarbamate (NCDC), a phospholipase C (PLC) inhibitor. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 148-152 arginine vasopressin Rattus norvegicus 26-29 9329977-6 1997 In the third series of experiments, treatment with 2-nitro-4-carboxyphenyl-N, N-diphenyl-carbamate (200 microM), a phospholipase C inhibitor, blocked both AA and EA constriction by AngII (n = 6 for each). 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 51-98 angiotensinogen Rattus norvegicus 181-186 9249599-4 1997 Inhibition of phospholipase C by treatment with 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC), inhibition of protein kinase C (PKC) by staurosporine, or long-term (24 h) treatment with phorbol 12-myristate 13-acetate (PMA) to downregulate PKC abolished most of the osmo-induced, dihydropyridine-sensitive calcium influx signal. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 95-99 LOC100009319 Oryctolagus cuniculus 14-29 7498966-6 1995 The phospholipase C inhibitor 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate (10 mumol/L) inhibited contractions induced by flow and histamine but not by K+. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 30-75 LOC100009319 Oryctolagus cuniculus 4-19 7687441-2 1993 2-Nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC), the inhibitor of phospholipase C (PLC), abolished the ouabain inotropy in rabbit papillary muscles. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 0-45 LOC100009319 Oryctolagus cuniculus 71-86 7875771-4 1995 On the other hand, a phospholipase C inhibitor, 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate, and protein kinase C inhibitors, 1-5-(isoquinolinylsulfonyl)-2-methylpiperazine and chelerythrine, significantly inhibited the pressure-induced endothelin-1 increase. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 48-93 endothelin 1 Homo sapiens 239-251 7687441-2 1993 2-Nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC), the inhibitor of phospholipase C (PLC), abolished the ouabain inotropy in rabbit papillary muscles. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 0-45 LOC100009319 Oryctolagus cuniculus 88-91 7687441-2 1993 2-Nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC), the inhibitor of phospholipase C (PLC), abolished the ouabain inotropy in rabbit papillary muscles. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 47-51 LOC100009319 Oryctolagus cuniculus 71-86 7687441-2 1993 2-Nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC), the inhibitor of phospholipase C (PLC), abolished the ouabain inotropy in rabbit papillary muscles. 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 47-51 LOC100009319 Oryctolagus cuniculus 88-91 1330625-7 1992 Furthermore, the contractile response to bradykinin in basilar artery was significantly inhibited by 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate (10(-5) M), H-7 (10(-5) M) and TMB-8 (10(-5) M), but not by indomethacin (10(-5) M) or nordihydroquariaretic acid (10(-5) M). 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 101-146 kininogen 1 Canis lupus familiaris 41-51 8498568-6 1993 However, contractions were depressed by approximately 50% when vessels were pretreated with the phospholipase C/serine esterase inhibitor 2-nitro-4-carboxy-phenyl-N,N-diphenylcarbamate (50 microM). 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 138-184 LOC100009319 Oryctolagus cuniculus 96-111 2015423-4 1991 The 5-HT-induced accumulation of DG could be blocked with the putative phospholipase C inhibitor 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC; 70 microM), but not with the protein kinase C inhibitor, 1-(5-isoquinolinesulphonyl)-2-methyl piperazine (H7; 50 microM). 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 97-142 LOC100009319 Oryctolagus cuniculus 71-86 2015423-4 1991 The 5-HT-induced accumulation of DG could be blocked with the putative phospholipase C inhibitor 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate (NCDC; 70 microM), but not with the protein kinase C inhibitor, 1-(5-isoquinolinesulphonyl)-2-methyl piperazine (H7; 50 microM). 2-nitro-4-carboxyphenyl-N,N-diphenylcarbamate 144-148 LOC100009319 Oryctolagus cuniculus 71-86